id	LEN-1_fpkm	LEN-2_fpkm	LEN-3_fpkm	TCP-1_fpkm	TCP-2_fpkm	TCP-3_fpkm	LEN-1_count	LEN-2_count	LEN-3_count	TCP-1_count	TCP-2_count	TCP-3_count	Symbol	Description	KEGG_A_class	KEGG_B_class	Pathway	K_ID	GO Component	GO Function	GO Process	TF_family
ENSG00000000003	28.877	28.707	28.679	27.256	25.593	26.491	2240	2135	1553	1547	1620	1399	TSPAN6	tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0039532//negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000000005	0	0	0	0.054	0	0	0	0	0	1	0	0	TNMD	tenomodulin [Source:HGNC Symbol;Acc:HGNC:17757]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001886//endothelial cell morphogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0016525//negative regulation of angiogenesis	--
ENSG00000000419	8.845	7.49	8.153	8.239	7.357	8.019	193	165.39	133.24	135	138	129	DPM1	"dolichyl-phosphate mannosyltransferase subunit 1, catalytic [Source:HGNC Symbol;Acc:HGNC:3005]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K00721;K00721	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0033185//dolichol-phosphate-mannose synthase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0004582//dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0043178//alcohol binding	GO:0006486//protein glycosylation;GO:0006506//GPI anchor biosynthetic process;GO:0019348//dolichol metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0035268//protein mannosylation;GO:0035269//protein O-linked mannosylation;GO:0097502//mannosylation	--
ENSG00000000457	3.446	3.198	4.516	2.673	3.119	3.66	256.81	230.69	267.19	177.62	219.85	210.1	SCYL3	SCY1 like pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:19285]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0016477//cell migration;GO:0021522//spinal cord motor neuron differentiation;GO:0034613//cellular protein localization;GO:0048666//neuron development	--
ENSG00000000460	3.205	3.123	2.878	1.777	1.879	3.501	145.19	168.31	82.81	62.38	78.15	104.9	C1orf112	chromosome 1 open reading frame 112 [Source:HGNC Symbol;Acc:HGNC:25565]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000000938	0	0	0	0	0.022	0	0	0	0	0	1	0	FGR	"FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697]"	Organismal Systems	Immune system	ko04062//Chemokine signaling pathway	K08891	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016235//aggresome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032587//ruffle membrane;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0034987//immunoglobulin receptor binding;GO:0034988//Fc-gamma receptor I complex binding	GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0009615//response to virus;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030282//bone mineralization;GO:0030335//positive regulation of cell migration;GO:0032815//negative regulation of natural killer cell activation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043306//positive regulation of mast cell degranulation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0045859//regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0048705//skeletal system morphogenesis;GO:0050764//regulation of phagocytosis;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000000971	64.412	52.996	46.597	39.382	44.574	47.573	4317.26	3567.38	2254.63	2003.58	2560.8	2215.1	CFH	complement factor H [Source:HGNC Symbol;Acc:HGNC:4883]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K04004;K04004	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1905370//serine-type endopeptidase complex	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0043395//heparan sulfate proteoglycan binding	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0030449//regulation of complement activation;GO:0030451//regulation of complement activation, alternative pathway;GO:0045087//innate immune response;GO:1903659//regulation of complement-dependent cytotoxicity"	--
ENSG00000001036	69.691	73.116	75.596	88.085	74.818	70.094	3444	3632	2762	3206	3127	2523	FUCA2	alpha-L-fucosidase 2 [Source:HGNC Symbol;Acc:HGNC:4008]	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K01206;K01206	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005788//endoplasmic reticulum lumen;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	"GO:0004560//alpha-L-fucosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006004//fucose metabolic process;GO:0008152//metabolic process;GO:0009617//response to bacterium;GO:0016139//glycoside catabolic process;GO:2000535//regulation of entry of bacterium into host cell	--
ENSG00000001084	14.501	15.021	14.876	10.408	13.543	13.018	992	961	681	578	744	632	GCLC	glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311]	Metabolism;Metabolism;Metabolism;Cellular Processes	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism;Cell growth and death	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00270//Cysteine and methionine metabolism;ko04216//Ferroptosis	K11204;K11204;K11204;K11204	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0017109//glutamate-cysteine ligase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004357//glutamate-cysteine ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016595//glutamate binding;GO:0016874//ligase activity;GO:0043531//ADP binding;GO:0044877//protein-containing complex binding	"GO:0006534//cysteine metabolic process;GO:0006536//glutamate metabolic process;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0007584//response to nutrient;GO:0009408//response to heat;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0014823//response to activity;GO:0019752//carboxylic acid metabolic process;GO:0019852//L-ascorbic acid metabolic process;GO:0031397//negative regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0044752//response to human chorionic gonadotropin;GO:0045454//cell redox homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046685//response to arsenic-containing substance;GO:0046686//response to cadmium ion;GO:0051409//response to nitrosative stress;GO:0051900//regulation of mitochondrial depolarization;GO:0070555//response to interleukin-1;GO:0071260//cellular response to mechanical stimulus;GO:0071333//cellular response to glucose stimulus;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0097069//cellular response to thyroxine stimulus;GO:0097746//blood vessel diameter maintenance;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2000490//negative regulation of hepatic stellate cell activation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000001167	13.239	12.775	12.432	9.424	12.358	10.59	1181	1148	787	617	880	706	NFYA	nuclear transcription factor Y subunit alpha [Source:HGNC Symbol;Acc:HGNC:7804]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Neurodegenerative disease;Immune system	ko05152//Tuberculosis;ko05017//Spinocerebellar ataxia;ko04612//Antigen processing and presentation	K08064;K08064;K08064	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0035065//regulation of histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0080182//histone H3-K4 trimethylation"	NF-YA
ENSG00000001460	6.743	5.832	6.853	6.351	5.959	6.263	363	322	272	254	272	245	STPG1	sperm tail PG-rich repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28070]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003674//molecular_function	GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process	--
ENSG00000001461	11.059	10.445	11.426	9.644	10.834	10.761	1173	1157	892	796	1006	830	NIPAL3	NIPA like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25233]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity	GO:0015693//magnesium ion transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000001497	13.222	13.758	13.652	14.344	14.342	12.843	691	697	521	525	600	458	LAS1L	LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030687//preribosome, large subunit precursor;GO:0071339//MLL1 complex;GO:0090730//Las1 complex"	GO:0003723//RNA binding;GO:0004519//endonuclease activity;GO:0005515//protein binding	GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000001561	10.06	7.127	7.492	6.026	7.041	10.016	969	690	533	430	573	702	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 [Source:HGNC Symbol;Acc:HGNC:3359]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K18424;K18424	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047710//bis(5'-adenosyl)-triphosphatase activity	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030194//positive regulation of blood coagulation;GO:0046130//purine ribonucleoside catabolic process	--
ENSG00000001617	8.744	8.491	7.996	7.487	8.978	7.767	539	510	353	348	436	347	SEMA3F	semaphorin 3F [Source:HGNC Symbol;Acc:HGNC:10728]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0021612//facial nerve structural organization;GO:0021637//trigeminal nerve structural organization;GO:0021675//nerve development;GO:0021785//branchiomotor neuron axon guidance;GO:0030335//positive regulation of cell migration;GO:0036486//ventral trunk neural crest cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048846//axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0061549//sympathetic ganglion development;GO:0071526//semaphorin-plexin signaling pathway;GO:0097490//sympathetic neuron projection extension;GO:0097491//sympathetic neuron projection guidance;GO:0099175//regulation of postsynapse organization;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000001626	0.098	0.035	0.193	0	0.067	0	6	3	4	0	2	0	CFTR	CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Signal transduction;Cellular community - eukaryotes;Signal transduction;Digestive system;Digestive system;Digestive system;Infectious disease: bacterial;Membrane transport	ko04024//cAMP signaling pathway;ko04530//Tight junction;ko04152//AMPK signaling pathway;ko04972//Pancreatic secretion;ko04976//Bile secretion;ko04971//Gastric acid secretion;ko05110//Vibrio cholerae infection;ko02010//ABC transporters	K05031;K05031;K05031;K05031;K05031;K05031;K05031;K05031	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0034707//chloride channel complex;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0005254//chloride channel activity;GO:0005260//intracellularly ATP-gated chloride channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity;GO:0017081//chloride channel regulator activity;GO:0019869//chloride channel inhibitor activity;GO:0019899//enzyme binding;GO:0030165//PDZ domain binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0051087//chaperone binding;GO:0106138//Sec61 translocon complex binding;GO:0140359//ABC-type transporter activity	GO:0006695//cholesterol biosynthetic process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0030301//cholesterol transport;GO:0034220//ion transmembrane transport;GO:0034976//response to endoplasmic reticulum stress;GO:0035377//transepithelial water transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045921//positive regulation of exocytosis;GO:0048240//sperm capacitation;GO:0050891//multicellular organismal water homeostasis;GO:0051454//intracellular pH elevation;GO:0055085//transmembrane transport;GO:0060081//membrane hyperpolarization;GO:0070175//positive regulation of enamel mineralization;GO:0071320//cellular response to cAMP;GO:0097186//amelogenesis;GO:1902161//positive regulation of cyclic nucleotide-gated ion channel activity;GO:1902476//chloride transmembrane transport;GO:1902943//positive regulation of voltage-gated chloride channel activity;GO:1904322//cellular response to forskolin	--
ENSG00000001629	18.979	17.848	16.202	12.687	12.578	11.423	1665	1346	1002	775	943	977	ANKIB1	ankyrin repeat and IBR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22215]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000001630	57.582	47.423	56.149	60.26	59.731	73.768	3385.01	2912	2545.04	2726	3061	3238.8	CYP51A1	cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K05917;K05917	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008398//sterol 14-demethylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0042177//negative regulation of protein catabolic process;GO:0050709//negative regulation of protein secretion;GO:0070988//demethylation;GO:1900222//negative regulation of amyloid-beta clearance	--
ENSG00000001631	8.969	5.291	4.816	4.468	5.984	7.185	501.37	386	269.57	254	370	297.86	KRIT1	KRIT1 ankyrin repeat containing [Source:HGNC Symbol;Acc:HGNC:1573]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17705	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030054//cell junction	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008017//microtubule binding;GO:0030695//GTPase regulator activity"	GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0003158//endothelium development;GO:0007264//small GTPase mediated signal transduction;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0033622//integrin activation;GO:0045454//cell redox homeostasis;GO:0045765//regulation of angiogenesis;GO:0050790//regulation of catalytic activity;GO:2000114//regulation of establishment of cell polarity;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000002016	2.328	2.967	2.099	1.155	1.849	2.123	89	83	74	40	89	72	RAD52	"RAD52 homolog, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:9824]"	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10873	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0000730//DNA recombinase assembly;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006312//mitotic recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0034599//cellular response to oxidative stress;GO:0045002//double-strand break repair via single-strand annealing;GO:2000819//regulation of nucleotide-excision repair	--
ENSG00000002330	45.943	49.043	61.113	66.128	54.045	63.255	908.84	954.99	894.98	946.87	877.96	825.9	BAD	BCL2 associated agonist of cell death [Source:HGNC Symbol;Acc:HGNC:936]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cancer: overview;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Signal transduction;Cancer: specific types;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Endocrine system;Cell growth and death;Endocrine system;Nervous system;Infectious disease: parasitic;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05020//Prion disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko05162//Measles;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko05145//Toxoplasmosis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer	K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158;K02158	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030346//protein phosphatase 2B binding;GO:0043422//protein kinase B binding;GO:0071889//14-3-3 protein binding	GO:0001666//response to hypoxia;GO:0001836//release of cytochrome c from mitochondria;GO:0006007//glucose catabolic process;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007283//spermatogenesis;GO:0008283//cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0009749//response to glucose;GO:0010033//response to organic substance;GO:0010508//positive regulation of autophagy;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0014070//response to organic cyclic compound;GO:0019221//cytokine-mediated signaling pathway;GO:0021987//cerebral cortex development;GO:0032024//positive regulation of insulin secretion;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0033133//positive regulation of glucokinase activity;GO:0033574//response to testosterone;GO:0034201//response to oleic acid;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042542//response to hydrogen peroxide;GO:0042593//glucose homeostasis;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043200//response to amino acid;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044342//type B pancreatic cell proliferation;GO:0045471//response to ethanol;GO:0045579//positive regulation of B cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0045862//positive regulation of proteolysis;GO:0046031//ADP metabolic process;GO:0046034//ATP metabolic process;GO:0046902//regulation of mitochondrial membrane permeability;GO:0046931//pore complex assembly;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051384//response to glucocorticoid;GO:0051592//response to calcium ion;GO:0071247//cellular response to chromate;GO:0071260//cellular response to mechanical stimulus;GO:0071316//cellular response to nicotine;GO:0071396//cellular response to lipid;GO:0071456//cellular response to hypoxia;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1901216//positive regulation of neuron death;GO:1901423//response to benzene;GO:1902220//positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:1904710//positive regulation of granulosa cell apoptotic process;GO:2000078//positive regulation of type B pancreatic cell development	--
ENSG00000002549	20.323	20.382	21.805	18.492	16.256	18.778	804	822	648	548	555	555	LAP3	leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00330//Arginine and proline metabolism	K11142;K11142;K11142	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0019538//protein metabolic process	--
ENSG00000002586	93.275	106.346	97.73	90.204	89.257	82.948	2218	2515	1693	1577	1785	1422	CD99	CD99 molecule (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:7082]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06520;K06520	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0034109//homotypic cell-cell adhesion;GO:0072683//T cell extravasation;GO:2000391//positive regulation of neutrophil extravasation	--
ENSG00000002587	0.108	0.08	0.33	0.182	0.183	0.12	16	12	13	20	23	13	HS3ST1	heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K01024	GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000002726	0	0	0	0	0	0	0	0	0	0	0	0	AOC1	amine oxidase copper containing 1 [Source:HGNC Symbol;Acc:HGNC:80]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00380//Tryptophan metabolism;ko00340//Histidine metabolism	K11182;K11182;K11182;K11182	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005777//peroxisome;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	"GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008131//primary amine oxidase activity;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0048038//quinone binding;GO:0052597//diamine oxidase activity;GO:0052598//histamine oxidase activity;GO:0052599//methylputrescine oxidase activity;GO:0052600//propane-1,3-diamine oxidase activity"	GO:0009308//amine metabolic process;GO:0009445//putrescine metabolic process;GO:0035874//cellular response to copper ion starvation;GO:0046677//response to antibiotic;GO:0071280//cellular response to copper ion;GO:0071420//cellular response to histamine;GO:0071504//cellular response to heparin;GO:0097185//cellular response to azide	--
ENSG00000002745	0	0.015	0.021	0.062	0.018	0	0	1	1	3	1	0	WNT16	Wnt family member 16 [Source:HGNC Symbol;Acc:HGNC:16267]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05202//Transcriptional misregulation in cancer;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558;K01558	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity	GO:0003408//optic cup formation involved in camera-type eye development;GO:0007275//multicellular organism development;GO:0010628//positive regulation of gene expression;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0043616//keratinocyte proliferation;GO:0045165//cell fate commitment;GO:0046330//positive regulation of JNK cascade;GO:0046849//bone remodeling;GO:0060070//canonical Wnt signaling pathway;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060548//negative regulation of cell death;GO:0090399//replicative senescence;GO:0090403//oxidative stress-induced premature senescence	--
ENSG00000002746	0.029	0.047	0.063	0.025	0.121	0	5	6	5	2	11	0	HECW1	"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:22195]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0048814//regulation of dendrite morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000002822	9.728	9.227	8.869	9.311	9.329	8.565	538	516	364.21	358	432	344	MAD1L1	mitotic arrest deficient 1 like 1 [Source:HGNC Symbol;Acc:HGNC:6762]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: viral;Cancer: overview;Cell growth and death;Cell growth and death;Endocrine system	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K06679;K06679;K06679;K06679;K06679	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0043229//intracellular organelle;GO:0044615//nuclear pore nuclear basket;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole;GO:1990706//MAD1 complex;GO:1990728//mitotic spindle assembly checkpoint MAD1-MAD2 complex"	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043515//kinetochore binding	GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0042130//negative regulation of T cell proliferation;GO:0048538//thymus development;GO:0051220//cytoplasmic sequestering of protein;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0090235//regulation of metaphase plate congression;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1901990//regulation of mitotic cell cycle phase transition;GO:1902426//deactivation of mitotic spindle assembly checkpoint	--
ENSG00000002834	47.088	47.071	55.365	59.051	54.719	57.881	3817	3840	3317	3543	3751	3416	LASP1	LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030864//cortical actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0006811//ion transport;GO:0034220//ion transmembrane transport	--
ENSG00000002919	8.725	7.359	9.419	10.179	9.386	8.984	315	279	257	273	264	249	SNX11	sorting nexin 11 [Source:HGNC Symbol;Acc:HGNC:14975]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016050//vesicle organization	--
ENSG00000002933	20.37	20.88	18.204	22.488	25.295	19.332	454	474	305	380	484	314	TMEM176A	transmembrane protein 176A [Source:HGNC Symbol;Acc:HGNC:24930]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:2001199//negative regulation of dendritic cell differentiation	--
ENSG00000003056	21.091	18.637	16.029	18.195	17.373	25.929	848.83	837.75	553.34	586.73	653.82	645.47	M6PR	"mannose-6-phosphate receptor, cation dependent [Source:HGNC Symbol;Acc:HGNC:6752]"	Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Transport and catabolism;Transport and catabolism	ko05132//Salmonella infection;ko04145//Phagosome;ko04142//Lysosome	K10089;K10089;K10089	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:1905394//retromer complex binding	GO:0006622//protein targeting to lysosome;GO:0006898//receptor-mediated endocytosis;GO:0007041//lysosomal transport;GO:0008333//endosome to lysosome transport;GO:0033299//secretion of lysosomal enzymes	--
ENSG00000003096	4.403	3.552	3.214	3.255	4.109	3.36	279	237	148	149	234	156	KLHL13	kelch like family member 13 [Source:HGNC Symbol;Acc:HGNC:22931]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10447	GO:0005829//cytosol;GO:0030496//midbody;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0097602//cullin family protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0032465//regulation of cytokinesis;GO:0051301//cell division	--
ENSG00000003137	0.336	0.839	0.361	1.983	0.488	0.448	29	25	22	54	39	30	CYP26B1	cytochrome P450 family 26 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:20581]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K12664;K12664	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0001972//retinoic acid binding;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0001709//cell fate determination;GO:0001768//establishment of T cell polarity;GO:0001822//kidney development;GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006954//inflammatory response;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0009954//proximal/distal pattern formation;GO:0010628//positive regulation of gene expression;GO:0016125//sterol metabolic process;GO:0030326//embryonic limb morphogenesis;GO:0032526//response to retinoic acid;GO:0033189//response to vitamin A;GO:0034653//retinoic acid catabolic process;GO:0042573//retinoic acid metabolic process;GO:0043587//tongue morphogenesis;GO:0045580//regulation of T cell differentiation;GO:0048384//retinoic acid receptor signaling pathway;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0060349//bone morphogenesis;GO:0061436//establishment of skin barrier;GO:0070268//cornification;GO:0071300//cellular response to retinoic acid;GO:2001037//positive regulation of tongue muscle cell differentiation	--
ENSG00000003147	4.455	4.446	4.415	3.81	4.006	4.015	175	176	131	116	159	141	ICA1	islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343]	Human Diseases	Endocrine and metabolic disease	ko04940//Type I diabetes mellitus	K19863	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0140090//membrane curvature sensor activity	GO:0006836//neurotransmitter transport;GO:0050796//regulation of insulin secretion;GO:0051049//regulation of transport	--
ENSG00000003249	7.935	8.377	9.072	8.851	7.937	8.843	335	360	276	280	281	271	DBNDD1	dysbindin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28455]	-	-	-	-	GO:0005737//cytoplasm	-	GO:0006469//negative regulation of protein kinase activity	--
ENSG00000003393	12.833	13.48	14.101	12.283	12.728	15.206	1586	1619	1263	1103	1313	1391	ALS2	alsin Rho guanine nucleotide exchange factor ALS2 [Source:HGNC Symbol;Acc:HGNC:443]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K04575;K04575	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043539//protein serine/threonine kinase activator activity	"GO:0001662//behavioral fear response;GO:0001701//in utero embryonic development;GO:0001881//receptor recycling;GO:0006979//response to oxidative stress;GO:0007032//endosome organization;GO:0007041//lysosomal transport;GO:0007409//axonogenesis;GO:0007528//neuromuscular junction development;GO:0007626//locomotory behavior;GO:0008104//protein localization;GO:0008219//cell death;GO:0016050//vesicle organization;GO:0016197//endosomal transport;GO:0016601//Rac protein signal transduction;GO:0035022//positive regulation of Rac protein signal transduction;GO:0035249//synaptic transmission, glutamatergic;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0045860//positive regulation of protein kinase activity;GO:0048812//neuron projection morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051036//regulation of endosome size;GO:0051260//protein homooligomerization;GO:0071902//positive regulation of protein serine/threonine kinase activity"	--
ENSG00000003400	0.098	0.062	0.081	0	0.091	0.09	4	3	7	0	9	5	CASP10	caspase 10 [Source:HGNC Symbol;Acc:HGNC:1500]	Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Infectious disease: viral;Cell growth and death;Signal transduction;Immune system	ko05152//Tuberculosis;ko05161//Hepatitis B;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko04622//RIG-I-like receptor signaling pathway	K04400;K04400;K04400;K04400;K04400	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031265//CD95 death-inducing signaling complex;GO:0097342//ripoptosome	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0035877//death effector domain binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010941//regulation of cell death;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0097190//apoptotic signaling pathway;GO:0097194//execution phase of apoptosis	--
ENSG00000003402	12.572	13.118	11.169	11.998	13.103	13.649	1391.34	1145.97	933.24	848.79	1078.88	930.57	CFLAR	CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]	Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases	Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Cell growth and death;Signal transduction;Infectious disease: parasitic	ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05142//Chagas disease	K04724;K04724;K04724;K04724;K04724;K04724;K04724	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031264//death-inducing signaling complex;GO:0031265//CD95 death-inducing signaling complex;GO:0045121//membrane raft;GO:0097342//ripoptosome	GO:0002020//protease binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008234//cysteine-type peptidase activity;GO:0044877//protein-containing complex binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0001666//response to hypoxia;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007519//skeletal muscle tissue development;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010941//regulation of cell death;GO:0010976//positive regulation of neuron projection development;GO:0014732//skeletal muscle atrophy;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0014866//skeletal myofibril assembly;GO:0032869//cellular response to insulin stimulus;GO:0033574//response to testosterone;GO:0042060//wound healing;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043403//skeletal muscle tissue regeneration;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060544//regulation of necroptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071456//cellular response to hypoxia;GO:0071549//cellular response to dexamethasone stimulus;GO:0071732//cellular response to nitric oxide;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0097190//apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:1901740//negative regulation of myoblast fusion;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903055//positive regulation of extracellular matrix organization;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903845//negative regulation of cellular response to transforming growth factor beta stimulus;GO:1903944//negative regulation of hepatocyte apoptotic process;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:2000347//positive regulation of hepatocyte proliferation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000003436	1.537	1.479	0.896	0.782	0.851	1.711	65	71	23	28	36	29	TFPI	tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03909	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030195//negative regulation of blood coagulation;GO:0071383//cellular response to steroid hormone stimulus	--
ENSG00000003509	3.565	3.906	3.795	3.274	3.012	2.671	151	163	114	107	112	77	NDUFAF7	NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18164	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity	"GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0032259//methylation;GO:0032981//mitochondrial respiratory chain complex I assembly"	--
ENSG00000003756	37.127	35.526	38.472	28.812	32.858	33.458	2335	2253	1650	1357	1765	1510	RBM5	RNA binding motif protein 5 [Source:HGNC Symbol;Acc:HGNC:9902]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process"	--
ENSG00000003987	1.892	1.447	1.511	1.267	1.683	1.73	182.46	149.24	113.52	99.51	123.54	108.62	MTMR7	myotubularin related protein 7 [Source:HGNC Symbol;Acc:HGNC:7454]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18083;K18083;K18083	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016312//inositol bisphosphate phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0052866//phosphatidylinositol phosphate phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000003989	64.585	54.886	57.331	58.142	64.01	70.609	9496	8057	6273	6557	7930	7486	SLC7A2	solute carrier family 7 member 2 [Source:HGNC Symbol;Acc:HGNC:11060]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0000064//L-ornithine transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015189//L-lysine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006865//amino acid transport;GO:0015807//L-amino acid transport;GO:0055085//transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:0097638//L-arginine import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903352//L-ornithine transmembrane transport;GO:1903401//L-lysine transmembrane transport;GO:1903826//arginine transmembrane transport	--
ENSG00000004059	62.992	60.495	60.042	69.313	61.795	70.306	1313	1272	932	1071	1104	1052	ARF5	ADP ribosylation factor 5 [Source:HGNC Symbol;Acc:HGNC:658]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07940	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport"	--
ENSG00000004139	5.442	7.869	3.733	7.262	7.95	6.46	652.47	797.36	506.12	591.98	680.49	554.93	SARM1	sterile alpha and TIR motif containing 1 [Source:HGNC Symbol;Acc:HGNC:17074]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031315//extrinsic component of mitochondrial outer membrane;GO:0042995//cell projection;GO:0045202//synapse	"GO:0003953//NAD+ nucleosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0035591//signaling adaptor activity;GO:0042802//identical protein binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0002376//immune system process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0009749//response to glucose;GO:0019677//NAD catabolic process;GO:0030154//cell differentiation;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0044249//cellular biosynthetic process;GO:0044281//small molecule metabolic process;GO:0045087//innate immune response;GO:0048678//response to axon injury;GO:0048814//regulation of dendrite morphogenesis;GO:1901214//regulation of neuron death;GO:1901216//positive regulation of neuron death;GO:1901565//organonitrogen compound catabolic process;GO:1901576//organic substance biosynthetic process	--
ENSG00000004142	40.868	38.463	41.768	44.097	41.548	45.671	2159.17	2134.49	1674.6	1771.46	1878.24	1840.32	POLDIP2	DNA polymerase delta interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23781]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0030496//midbody;GO:0042645//mitochondrial nucleoid;GO:0072686//mitotic spindle	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016242//negative regulation of macroautophagy;GO:0045931//positive regulation of mitotic cell cycle;GO:0051894//positive regulation of focal adhesion assembly;GO:0070584//mitochondrion morphogenesis;GO:0070987//error-free translesion synthesis;GO:0090307//mitotic spindle assembly;GO:1903490//positive regulation of mitotic cytokinesis;GO:1904531//positive regulation of actin filament binding;GO:1990874//vascular associated smooth muscle cell proliferation;GO:2001108//positive regulation of Rho guanyl-nucleotide exchange factor activity	--
ENSG00000004399	37.997	39.736	35.163	36.135	37.169	29.946	2987	3141	2221	2410	2863	2089	PLXND1	plexin D1 [Source:HGNC Symbol;Acc:HGNC:9107]	-	-	-	-	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0031258//lamellipodium membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity;GO:0019904//protein domain specific binding	GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001822//kidney development;GO:0003151//outflow tract morphogenesis;GO:0003279//cardiac septum development;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007416//synapse assembly;GO:0008360//regulation of cell shape;GO:0030334//regulation of cell migration;GO:0032092//positive regulation of protein binding;GO:0035904//aorta development;GO:0043087//regulation of GTPase activity;GO:0043542//endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0050772//positive regulation of axonogenesis;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0060976//coronary vasculature development;GO:0071526//semaphorin-plexin signaling pathway;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000004455	45.009	46.076	52.296	46.636	44.855	45.352	1774	1701	1429	1294	1471	1327	AK2	adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0036126//sperm flagellum;GO:0070062//extracellular exosome;GO:0097226//sperm mitochondrial sheath	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006172//ADP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046033//AMP metabolic process;GO:0046034//ATP metabolic process;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000004468	0.102	0.06	0.174	0.136	0.304	0.012	6	7	15	5	10	1	CD38	CD38 molecule [Source:HGNC Symbol;Acc:HGNC:1667]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Immune system;Endocrine system;Digestive system;Digestive system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko04640//Hematopoietic cell lineage;ko04921//Oxytocin signaling pathway;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko00760//Nicotinate and nicotinamide metabolism	K01242;K01242;K01242;K01242;K01242;K01242;K01242	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030667//secretory granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0003953//NAD+ nucleosidase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016849//phosphorus-oxygen lyase activity;GO:0042802//identical protein binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	"GO:0001666//response to hypoxia;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0010977//negative regulation of neuron projection development;GO:0014824//artery smooth muscle contraction;GO:0019674//NAD metabolic process;GO:0030307//positive regulation of cell growth;GO:0030890//positive regulation of B cell proliferation;GO:0032024//positive regulation of insulin secretion;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032570//response to progesterone;GO:0033194//response to hydroperoxide;GO:0034097//response to cytokine;GO:0043066//negative regulation of apoptotic process;GO:0045779//negative regulation of bone resorption;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045907//positive regulation of vasoconstriction;GO:0050853//B cell receptor signaling pathway;GO:0060292//long-term synaptic depression;GO:0070555//response to interleukin-1;GO:0097190//apoptotic signaling pathway"	--
ENSG00000004478	40.608	40.98	48.33	45.987	45.35	54.099	3075	3110	2725	2589	2939	2928	FKBP4	FKBP prolyl isomerase 4 [Source:HGNC Symbol;Acc:HGNC:3720]	Organismal Systems	Endocrine system	ko04915//Estrogen signaling pathway	K09571	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030424//axon;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044295//axonal growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0030674//protein-macromolecule adaptor activity;GO:0031072//heat shock protein binding;GO:0032767//copper-dependent protein binding;GO:0035259//glucocorticoid receptor binding;GO:0048156//tau protein binding;GO:0051219//phosphoprotein binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0006463//steroid hormone receptor complex assembly;GO:0006825//copper ion transport;GO:0007566//embryo implantation;GO:0010977//negative regulation of neuron projection development;GO:0030521//androgen receptor signaling pathway;GO:0030850//prostate gland development;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0031115//negative regulation of microtubule polymerization;GO:0031503//protein-containing complex localization;GO:0046661//male sex differentiation;GO:0048608//reproductive structure development;GO:0061077//chaperone-mediated protein folding	--
ENSG00000004487	27.464	28.167	26.407	23.185	23.313	25.69	1759	1807	1249	1066	1262	1195	KDM1A	lysine demethylase 1A [Source:HGNC Symbol;Acc:HGNC:29079]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K11450	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex;GO:1990391//DNA repair complex"	GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0030374//nuclear receptor coactivator activity;GO:0032451//demethylase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0043426//MRF binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050681//androgen receptor binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061752//telomeric repeat-containing RNA binding;GO:0140297//DNA-binding transcription factor binding;GO:0140682//histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002052//positive regulation of neuroblast proliferation;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010976//positive regulation of neuron projection development;GO:0014070//response to organic cyclic compound;GO:0021987//cerebral cortex development;GO:0032091//negative regulation of protein binding;GO:0032880//regulation of protein localization;GO:0033169//histone H3-K9 demethylation;GO:0033184//positive regulation of histone ubiquitination;GO:0034644//cellular response to UV;GO:0034720//histone H3-K4 demethylation;GO:0035563//positive regulation of chromatin binding;GO:0042551//neuron maturation;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045793//positive regulation of cell size;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046098//guanine metabolic process;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0055001//muscle cell development;GO:0060765//regulation of androgen receptor signaling pathway;GO:0060992//response to fungicide;GO:0071320//cellular response to cAMP;GO:0071480//cellular response to gamma radiation;GO:0090308//regulation of DNA methylation-dependent heterochromatin assembly;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000648//positive regulation of stem cell proliferation"	--
ENSG00000004534	13.734	12.045	13.654	11.658	11.854	13.792	833	680	578	548	641	583	RBM6	RNA binding motif protein 6 [Source:HGNC Symbol;Acc:HGNC:9903]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing"	--
ENSG00000004660	0.481	0.698	0.439	0.297	0.612	0.378	35	52	24	16	37	20	CAMKK1	calcium/calmodulin dependent protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:1469]	Human Diseases	Substance dependence	ko05034//Alcoholism	K00908	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0045860//positive regulation of protein kinase activity	--
ENSG00000004700	7.296	6.989	5.668	4.11	5.7	5.026	465.63	365.94	257.06	182.03	300.48	208.61	RECQL	RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:9948]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0043138//3'-5' DNA helicase activity;GO:1990814//DNA/DNA annealing activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0032508//DNA duplex unwinding	--
ENSG00000004766	7.063	6.01	6.086	4.681	7.288	5.885	453	348	270	214	288	251	VPS50	VPS50 subunit of EARP/GARPII complex [Source:HGNC Symbol;Acc:HGNC:25956]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:1990745//EARP complex	GO:0000149//SNARE binding;GO:0005515//protein binding	"GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000004776	17.639	19.58	19.315	14.622	14.657	12.753	527	596	432	328	375	281	HSPB6	heat shock protein family B (small) member 6 [Source:HGNC Symbol;Acc:HGNC:26511]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005212//structural constituent of eye lens;GO:0042803//protein homodimerization activity;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0045766//positive regulation of angiogenesis;GO:0061077//chaperone-mediated protein folding	--
ENSG00000004777	0.467	0.584	1.842	1.442	0.711	1.479	41	53	37	35	53	66	ARHGAP33	Rho GTPase activating protein 33 [Source:HGNC Symbol;Acc:HGNC:23085]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex;GO:0043197//dendritic spine	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035091//phosphatidylinositol binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0009636//response to toxic substance;GO:0015031//protein transport;GO:0050790//regulation of catalytic activity;GO:0061001//regulation of dendritic spine morphogenesis	--
ENSG00000004779	54.707	57.327	64.688	66.828	62.964	80.458	754	795	659	683	734	807	NDUFAB1	NADH:ubiquinone oxidoreductase subunit AB1 [Source:HGNC Symbol;Acc:HGNC:7694]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955;K03955	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit;GO:0031966//mitochondrial membrane;GO:0070469//respirasome;GO:1990229//iron-sulfur cluster assembly complex	GO:0000035//acyl binding;GO:0000036//acyl carrier activity;GO:0005504//fatty acid binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0009060//aerobic respiration;GO:0009249//protein lipoylation;GO:0016226//iron-sulfur cluster assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0071704//organic substance metabolic process"	--
ENSG00000004799	1.071	0.866	1.106	1.012	1.458	1.104	80	65	61	56	92	60	PDK4	pyruvate dehydrogenase kinase 4 [Source:HGNC Symbol;Acc:HGNC:8812]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K00898	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006468//protein phosphorylation;GO:0006885//regulation of pH;GO:0008286//insulin receptor signaling pathway;GO:0009267//cellular response to starvation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0010565//regulation of cellular ketone metabolic process;GO:0010906//regulation of glucose metabolic process;GO:0016310//phosphorylation;GO:0042304//regulation of fatty acid biosynthetic process;GO:0042593//glucose homeostasis;GO:0042594//response to starvation;GO:0045124//regulation of bone resorption;GO:0046320//regulation of fatty acid oxidation;GO:0071398//cellular response to fatty acid;GO:0072593//reactive oxygen species metabolic process;GO:2000811//negative regulation of anoikis	--
ENSG00000004809	0	0	0.067	0	0.056	0.065	0	0	2	0	1	1	SLC22A16	solute carrier family 22 member 16 [Source:HGNC Symbol;Acc:HGNC:20302]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005275//amine transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015226//carnitine transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0015695//organic cation transport;GO:0015837//amine transport;GO:0015879//carnitine transport;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0046717//acid secretion;GO:0055085//transmembrane transport;GO:1902603//carnitine transmembrane transport	--
ENSG00000004838	3.196	2.772	2.425	1.504	0.836	1.503	111	98	57	41	26	33	ZMYND10	zinc finger MYND-type containing 10 [Source:HGNC Symbol;Acc:HGNC:19412]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0034451//centriolar satellite;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0044183//protein folding chaperone;GO:0046872//metal ion binding;GO:0060090//molecular adaptor activity	GO:0003341//cilium movement;GO:0006457//protein folding;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0044458//motile cilium assembly;GO:0061512//protein localization to cilium;GO:1905505//positive regulation of motile cilium assembly	--
ENSG00000004846	14.786	10.873	12.989	16.462	14.588	17.33	745	586	487	608	641	639	ABCB5	ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05660	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0001654//eye development;GO:0030154//cell differentiation;GO:0042391//regulation of membrane potential;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport	--
ENSG00000004848	0	0	0	0	0.02	0	0	0	0	0	1	0	ARX	aristaless related homeobox [Source:HGNC Symbol;Acc:HGNC:18060]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0010628//positive regulation of gene expression;GO:0021759//globus pallidus development;GO:0021772//olfactory bulb development;GO:0021800//cerebral cortex tangential migration;GO:0021831//embryonic olfactory bulb interneuron precursor migration;GO:0021846//cell proliferation in forebrain;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0042127//regulation of cell population proliferation;GO:0044241//lipid digestion;GO:0046622//positive regulation of organ growth;GO:0048484//enteric nervous system development;GO:0048666//neuron development;GO:0072148//epithelial cell fate commitment"	Homeobox
ENSG00000004864	20.569	21.773	20.714	24.099	23.675	22.655	1310	1364	961	1055	1278	1027	SLC25A13	solute carrier family 25 member 13 [Source:HGNC Symbol;Acc:HGNC:10983]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0003333//amino acid transmembrane transport;GO:0006094//gluconeogenesis;GO:0006754//ATP biosynthetic process;GO:0006839//mitochondrial transport;GO:0009066//aspartate family amino acid metabolic process;GO:0015810//aspartate transmembrane transport;GO:0015813//L-glutamate transmembrane transport;GO:0043490//malate-aspartate shuttle;GO:0045333//cellular respiration;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0070778//L-aspartate transmembrane transport	--
ENSG00000004866	11.633	11.2	10.554	9.692	9.413	11.619	502	538	331	361	368	394	ST7	suppression of tumorigenicity 7 [Source:HGNC Symbol;Acc:HGNC:11351]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0030198//extracellular matrix organization;GO:0045595//regulation of cell differentiation	--
ENSG00000004897	19.909	15.737	13.65	12.631	16.696	11.586	1398	1155	785	663	897	732	CDC27	cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03350;K03350;K03350;K03350;K03350	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0019903//protein phosphatase binding	GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000004939	0.013	0	0	0	0	0	1	0	0	0	0	0	SLC4A1	solute carrier family 4 member 1 (Diego blood group) [Source:HGNC Symbol;Acc:HGNC:11027]	Organismal Systems	Excretory system	ko04966//Collecting duct acid secretion	K06573	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030018//Z disc;GO:0030863//cortical cytoskeleton;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008509//anion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity;GO:0030492//hemoglobin binding;GO:0030506//ankyrin binding;GO:0042803//protein homodimerization activity;GO:0043495//protein-membrane adaptor activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0006873//cellular ion homeostasis;GO:0007596//blood coagulation;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0017121//plasma membrane phospholipid scrambling;GO:0035811//negative regulation of urine volume;GO:0045852//pH elevation;GO:0048821//erythrocyte development;GO:0050801//ion homeostasis;GO:0051354//negative regulation of oxidoreductase activity;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0098656//anion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1904539//negative regulation of glycolytic process through fructose-6-phosphate	--
ENSG00000004948	0.027	0	0	0	0	0	2	0	0	0	0	0	CALCR	calcitonin receptor [Source:HGNC Symbol;Acc:HGNC:1440]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Development and regeneration	ko04080//Neuroactive ligand-receptor interaction;ko04380//Osteoclast differentiation	K04576;K04576	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0150056//amylin receptor complex 1;GO:0150057//amylin receptor complex 2;GO:0150058//amylin receptor complex 3	GO:0001540//amyloid-beta binding;GO:0001635//calcitonin gene-related peptide receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004948//calcitonin receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0032841//calcitonin binding;GO:0097643//amylin receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010628//positive regulation of gene expression;GO:0010739//positive regulation of protein kinase A signaling;GO:0010942//positive regulation of cell death;GO:0030279//negative regulation of ossification;GO:0030316//osteoclast differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038041//cross-receptor inhibition within G protein-coupled receptor heterodimer;GO:0043488//regulation of mRNA stability;GO:0051384//response to glucocorticoid;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0097647//amylin receptor signaling pathway;GO:1904645//response to amyloid-beta;GO:1905665//positive regulation of calcium ion import across plasma membrane	--
ENSG00000004961	11.372	10.329	12.18	9.066	10.542	10.56	483	422	337	290	359	350	HCCS	holocytochrome c synthase [Source:HGNC Symbol;Acc:HGNC:4837]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01764;K01764	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0004408//holocytochrome-c synthase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0009887//animal organ morphogenesis;GO:0018063//cytochrome c-heme linkage	--
ENSG00000004975	18.206	19.084	21.685	20.74	19.761	20.84	917	999	808	795	907	786	DVL2	dishevelled segment polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:3086]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma;ko04330//Notch signaling pathway	K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016235//aggresome;GO:0016328//lateral plasma membrane;GO:0016604//nuclear body;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0045334//clathrin-coated endocytic vesicle	GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0043621//protein self-association	"GO:0001843//neural tube closure;GO:0001934//positive regulation of protein phosphorylation;GO:0003007//heart morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007379//segment specification;GO:0007507//heart development;GO:0016055//Wnt signaling pathway;GO:0022007//convergent extension involved in neural plate elongation;GO:0022603//regulation of anatomical structure morphogenesis;GO:0034613//cellular protein localization;GO:0035282//segmentation;GO:0035556//intracellular signal transduction;GO:0035567//non-canonical Wnt signaling pathway;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0044340//canonical Wnt signaling pathway involved in regulation of cell proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060029//convergent extension involved in organogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0150012//positive regulation of neuron projection arborization"	--
ENSG00000005001	0	0	0.094	0	0.165	0.078	0	0	2	0	4	1	PRSS22	serine protease 22 [Source:HGNC Symbol;Acc:HGNC:14368]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016504//peptidase activator activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0010952//positive regulation of peptidase activity	--
ENSG00000005007	27.611	28.774	32.437	30.271	29.461	32.282	3046	3191	2643	2474	2746	2591	UPF1	UPF1 RNA helicase and ATPase [Source:HGNC Symbol;Acc:HGNC:9962]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14326;K14326	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0044530//supraspliceosomal complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0036121//double-stranded DNA helicase activity;GO:0042162//telomeric DNA binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000294//nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006406//mRNA export from nucleus;GO:0006449//regulation of translational termination;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0032201//telomere maintenance via semi-conservative replication;GO:0032204//regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0044770//cell cycle phase transition;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0071044//histone mRNA catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1"	--
ENSG00000005020	1.457	1.237	1.309	1.119	1.249	1.364	116	99	77	66	84	79	SKAP2	src kinase associated phosphoprotein 2 [Source:HGNC Symbol;Acc:HGNC:15687]	Human Diseases	Infectious disease: bacterial	ko05135//Yersinia infection	K23471	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0042113//B cell activation;GO:0065003//protein-containing complex assembly	--
ENSG00000005022	104.243	101.618	108.179	131.417	111.554	118.478	2826	2769	2166	2639	2555	2337	SLC25A5	solute carrier family 25 member 5 [Source:HGNC Symbol;Acc:HGNC:10991]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia	K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005757//mitochondrial permeability transition pore complex;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042645//mitochondrial nucleoid;GO:0071817//MMXD complex	GO:0000295//adenine nucleotide transmembrane transporter activity;GO:0003723//RNA binding;GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0015207//adenine transmembrane transporter activity;GO:0015297//antiporter activity;GO:0017077//oxidative phosphorylation uncoupler activity;GO:0031625//ubiquitin protein ligase binding	GO:0007059//chromosome segregation;GO:0008284//positive regulation of cell population proliferation;GO:0015853//adenine transport;GO:0030183//B cell differentiation;GO:0030218//erythrocyte differentiation;GO:0046902//regulation of mitochondrial membrane permeability;GO:0051503//adenine nucleotide transport;GO:0055085//transmembrane transport;GO:0140021//mitochondrial ADP transmembrane transport;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1901526//positive regulation of mitophagy;GO:1902600//proton transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport;GO:1990830//cellular response to leukemia inhibitory factor;GO:1990845//adaptive thermogenesis	--
ENSG00000005059	4.908	5.528	4.596	4.174	3.583	3.09	227	257	157	143	140	104	MCUB	mitochondrial calcium uniporter dominant negative subunit beta [Source:HGNC Symbol;Acc:HGNC:26076]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:1990246//uniplex complex	GO:0019855//calcium channel inhibitor activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0036444//calcium import into the mitochondrion;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000005073	0	0.022	0	0.024	0	0	0	1	0	1	0	0	HOXA11	homeobox A11 [Source:HGNC Symbol;Acc:HGNC:5101]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K21951	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001759//organ induction;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007501//mesodermal cell fate specification;GO:0008584//male gonad development;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0010720//positive regulation of cell development;GO:0030326//embryonic limb morphogenesis;GO:0030850//prostate gland development;GO:0032330//regulation of chondrocyte differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0033574//response to testosterone;GO:0035115//embryonic forelimb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043627//response to estrogen;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048589//developmental growth;GO:0048856//anatomical structure development;GO:0060065//uterus development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060348//bone development;GO:0060351//cartilage development involved in endochondral bone morphogenesis"	Homeobox
ENSG00000005075	15.182	17.85	14.557	15.298	15.233	20.666	295.06	348.7	208.96	220.24	250.13	292.24	POLR2J	RNA polymerase II subunit J [Source:HGNC Symbol;Acc:HGNC:9197]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03008;K03008	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex"	GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0030275//LRR domain binding;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000005100	4.301	4.771	4.548	4.109	5.002	6.031	382	446	310	342	375	371	DHX33	DEAH-box helicase 33 [Source:HGNC Symbol;Acc:HGNC:16718]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K17820	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0061702//inflammasome complex;GO:0072559//NLRP3 inflammasome complex	GO:0000166//nucleotide binding;GO:0000182//rDNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043023//ribosomal large subunit binding;GO:0140297//DNA-binding transcription factor binding	GO:0006413//translational initiation;GO:0032481//positive regulation of type I interferon production;GO:0043410//positive regulation of MAPK cascade;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly	--
ENSG00000005102	0	0	0	0	0	0	0	0	0	0	0	0	MEOX1	mesenchyme homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7013]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001757//somite specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0008150//biological_process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060218//hematopoietic stem cell differentiation;GO:0061053//somite development;GO:0061056//sclerotome development"	Homeobox
ENSG00000005108	0.991	0.738	0.735	0.586	0.739	0.771	219	164	120	96	138	124	THSD7A	thrombospondin type 1 domain containing 7A [Source:HGNC Symbol;Acc:HGNC:22207]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0030154//cell differentiation;GO:0031532//actin cytoskeleton reorganization	--
ENSG00000005156	9.322	8.643	10.801	6.404	8.247	7.887	650.16	605.04	514.14	391.59	504.41	436.52	LIG3	DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10776	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0070421//DNA ligase III-XRCC1 complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003909//DNA ligase activity;GO:0003910//DNA ligase (ATP) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	"GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006266//DNA ligation;GO:0006273//lagging strand elongation;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006288//base-excision repair, DNA ligation;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007005//mitochondrion organization;GO:0007049//cell cycle;GO:0043504//mitochondrial DNA repair;GO:0051301//cell division;GO:0071897//DNA biosynthetic process;GO:0090298//negative regulation of mitochondrial DNA replication;GO:0097681//double-strand break repair via alternative nonhomologous end joining"	--
ENSG00000005175	6.163	4.624	4.541	3.261	4.283	3.692	376	257	186	149	212	179	RPAP3	RNA polymerase II associated protein 3 [Source:HGNC Symbol;Acc:HGNC:26151]	-	-	-	-	GO:0005829//cytosol;GO:0097255//R2TP complex;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0005515//protein binding	GO:0050821//protein stabilization	--
ENSG00000005187	0.189	0.117	0.212	0.364	0.318	0.375	9.95	6.17	4.72	6.99	6.1	10.66	ACSM3	acyl-CoA synthetase medium chain family member 3 [Source:HGNC Symbol;Acc:HGNC:10522]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015645//fatty acid ligase activity;GO:0016874//ligase activity;GO:0018729//propionate CoA-transferase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0043759//methylbutanoate-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0050218//propionate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0008217//regulation of blood pressure;GO:0042632//cholesterol homeostasis	--
ENSG00000005189	0.811	1.26	0.551	0.84	0.719	0.208	24	36	22	34	31	8	REXO5	RNA exonuclease 5 [Source:HGNC Symbol;Acc:HGNC:24661]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14570	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0016787//hydrolase activity	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000005194	18.741	20.868	21.805	22.859	24.397	22.98	755	781	642	650	717	666	CIAPIN1	cytokine induced apoptosis inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:28050]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	"GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006915//apoptotic process;GO:0016226//iron-sulfur cluster assembly;GO:0022900//electron transport chain;GO:0030097//hemopoiesis;GO:0043066//negative regulation of apoptotic process	--
ENSG00000005206	20.188	19.19	21.74	26.159	24.925	19.567	1151	1127	862	981	1114	835	SPPL2B	signal peptide peptidase like 2B [Source:HGNC Symbol;Acc:HGNC:30627]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0042803//protein homodimerization activity"	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0031293//membrane protein intracellular domain proteolysis;GO:0033619//membrane protein proteolysis;GO:0050776//regulation of immune response	--
ENSG00000005238	7.801	8.576	7.446	6.972	8.44	6.082	475	527	335	325	439	273	FAM214B	family with sequence similarity 214 member B [Source:HGNC Symbol;Acc:HGNC:25666]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000005243	8.841	9.771	8.269	9.528	7.281	5.425	150	165	100	120	103	70	COPZ2	COPI coat complex subunit zeta 2 [Source:HGNC Symbol;Acc:HGNC:19356]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	-	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport"	--
ENSG00000005249	5.776	4.33	4.388	3.529	3.45	4.724	442	333	248	200	223	263	PRKAR2B	protein kinase cAMP-dependent type II regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9392]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K04739	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097546//ciliary base;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030552//cAMP binding;GO:0031625//ubiquitin protein ligase binding;GO:0034236//protein kinase A catalytic subunit binding	GO:0001932//regulation of protein phosphorylation;GO:0006631//fatty acid metabolic process;GO:0007612//learning;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0045859//regulation of protein kinase activity;GO:0050804//modulation of chemical synaptic transmission;GO:0097332//response to antipsychotic drug;GO:0097338//response to clozapine;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000005302	6.447	7.567	6.58	8.729	7.06	5.676	342	376	224	209	270	215	MSL3	MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035267//NuA4 histone acetyltransferase complex;GO:0072487//MSL complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046972//histone acetyltransferase activity (H4-K16 specific)	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0016575//histone deacetylation;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000005339	17.392	17.649	16.079	13.972	16.384	13.739	2643	2756	1960	1726	2127	1792	CREBBP	CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Signal transduction;Cell growth and death;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Endocrine system;Cancer: specific types;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Nervous system;Signal transduction	"ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko05161//Hepatitis B;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04350//TGF-beta signaling pathway;ko05211//Renal cell carcinoma;ko04520//Adherens junction;ko04720//Long-term potentiation;ko04330//Notch signaling pathway"	K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498	GO:0000123//histone acetyltransferase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0001223//transcription coactivator binding;GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0031490//chromatin DNA binding;GO:0034212//peptide N-acetyltransferase activity;GO:0043426//MRF binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061733//peptide-lysine-N-acetyltransferase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006473//protein acetylation;GO:0007165//signal transduction;GO:0008589//regulation of smoothened signaling pathway;GO:0016573//histone acetylation;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031648//protein destabilization;GO:0034644//cellular response to UV;GO:0042592//homeostatic process;GO:0042733//embryonic digit morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0065003//protein-containing complex assembly;GO:1900034//regulation of cellular response to heat;GO:1990258//histone glutamine methylation"	--
ENSG00000005379	5.91	5.986	6.211	6.18	6.666	7.529	530	502	409	414	505	450	TSPOAP1	TSPO associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16831]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0044305//calyx of Held;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0030156//benzodiazepine receptor binding;GO:0099626//voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	GO:0008150//biological_process;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration	--
ENSG00000005381	0	0	0	0	0.035	0	0	0	0	0	2	0	MPO	myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218]	Human Diseases;Organismal Systems;Cellular Processes;Metabolism;Human Diseases	Cancer: overview;Immune system;Transport and catabolism;Xenobiotics biodegradation and metabolism;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko04145//Phagosome;ko00983//Drug metabolism - other enzymes;ko05221//Acute myeloid leukemia	K10789;K10789;K10789;K10789;K10789	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0030141//secretory granule;GO:0035578//azurophil granule lumen;GO:0042582//azurophil granule;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0097013//phagocytic vesicle lumen	GO:0003682//chromatin binding;GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0001878//response to yeast;GO:0002149//hypochlorous acid biosynthetic process;GO:0002679//respiratory burst involved in defense response;GO:0006952//defense response;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0009612//response to mechanical stimulus;GO:0019430//removal of superoxide radicals;GO:0032094//response to food;GO:0032496//response to lipopolysaccharide;GO:0034374//low-density lipoprotein particle remodeling;GO:0042742//defense response to bacterium;GO:0042744//hydrogen peroxide catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0050832//defense response to fungus;GO:0098869//cellular oxidant detoxification;GO:1990268//response to gold nanoparticle	--
ENSG00000005421	0.054	0.282	0.082	0.163	0.499	0.111	2	9	3	6	13	4	PON1	paraoxonase 1 [Source:HGNC Symbol;Acc:HGNC:9204]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004063//aryldialkylphosphatase activity;GO:0004064//arylesterase activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0102007//acyl-L-homoserine-lactone lactonohydrolase activity	GO:0006629//lipid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009636//response to toxic substance;GO:0010875//positive regulation of cholesterol efflux;GO:0016311//dephosphorylation;GO:0019439//aromatic compound catabolic process;GO:0031667//response to nutrient levels;GO:0032411//positive regulation of transporter activity;GO:0046395//carboxylic acid catabolic process;GO:0046434//organophosphate catabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0051099//positive regulation of binding;GO:0070542//response to fatty acid;GO:1902617//response to fluoride	--
ENSG00000005436	5.739	4.195	5.623	3.116	4.262	5.16	318	235	182	128	184	164	GCFC2	GC-rich sequence DNA-binding factor 2 [Source:HGNC Symbol;Acc:HGNC:1317]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0071008//U2-type post-mRNA release spliceosomal complex	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000390//spliceosomal complex disassembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045892//negative regulation of transcription, DNA-templated"	GCFC
ENSG00000005448	11.814	13.57	14.306	13.889	11.771	11.501	277	319	248	241	225	193	WDR54	WD repeat domain 54 [Source:HGNC Symbol;Acc:HGNC:25770]	-	-	-	-	GO:0031982//vesicle	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0002091//negative regulation of receptor internalization;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043408//regulation of MAPK cascade	--
ENSG00000005469	5.254	5.057	4.608	4.305	4.585	4.831	318	307	210	192	242	190	CROT	carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K05940	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008458//carnitine O-octanoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006091//generation of precursor metabolites and energy;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0009437//carnitine metabolic process;GO:0015908//fatty acid transport;GO:0015936//coenzyme A metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0051791//medium-chain fatty acid metabolic process	--
ENSG00000005471	0.195	0.286	0.347	0.358	0.361	0.248	16	23	20	21	24	14	ABCB4	ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]	Organismal Systems;Environmental Information Processing	Digestive system;Membrane transport	ko04976//Bile secretion;ko02010//ABC transporters	K05659;K05659	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft;GO:0046581//intercellular canaliculus;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005548//phospholipid transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0090554//phosphatidylcholine floppase activity;GO:0090555//phosphatidylethanolamine flippase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140359//ABC-type transporter activity	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0032376//positive regulation of cholesterol transport;GO:0032782//bile acid secretion;GO:0042908//xenobiotic transport;GO:0045332//phospholipid translocation;GO:0055085//transmembrane transport;GO:0055088//lipid homeostasis;GO:0061092//positive regulation of phospholipid translocation;GO:1901557//response to fenofibrate;GO:1903413//cellular response to bile acid;GO:2001140//positive regulation of phospholipid transport	--
ENSG00000005483	11.833	10.659	9.35	8.635	8.569	8.956	1470	1247	838	646	849	788	KMT2E	lysine methyltransferase 2E (inactive) [Source:HGNC Symbol;Acc:HGNC:18541]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K09189;K09189	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0035327//transcriptionally active chromatin	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0002446//neutrophil mediated immunity;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0030218//erythrocyte differentiation;GO:0042119//neutrophil activation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1905437//positive regulation of histone H3-K4 trimethylation"	--
ENSG00000005486	105.956	111.408	111.716	107.857	115.476	100.049	3816	4038	2979	2891	3522	2624	RHBDD2	rhomboid domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23082]	-	-	-	-	GO:0000139//Golgi membrane;GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0051787//misfolded protein binding;GO:1990381//ubiquitin-specific protease binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response	--
ENSG00000005513	10.729	9.804	8.226	8.855	9.779	8.435	687	631	389	420	529	393	SOX8	SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001755//neural crest cell migration;GO:0002009//morphogenesis of an epithelium;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0007422//peripheral nervous system development;GO:0008584//male gonad development;GO:0010628//positive regulation of gene expression;GO:0010817//regulation of hormone levels;GO:0014015//positive regulation of gliogenesis;GO:0014032//neural crest cell development;GO:0033690//positive regulation of osteoblast proliferation;GO:0035914//skeletal muscle cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045165//cell fate commitment;GO:0045444//fat cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0048469//cell maturation;GO:0048484//enteric nervous system development;GO:0048709//oligodendrocyte differentiation;GO:0060009//Sertoli cell development;GO:0060018//astrocyte fate commitment;GO:0060041//retina development in camera-type eye;GO:0060221//retinal rod cell differentiation;GO:0060612//adipose tissue development;GO:0061138//morphogenesis of a branching epithelium;GO:0072034//renal vesicle induction;GO:0072197//ureter morphogenesis;GO:0072289//metanephric nephron tubule formation;GO:0090184//positive regulation of kidney development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis"	HMG
ENSG00000005700	12.856	10.71	9.974	8.439	10.017	10.526	1581	1321	900	729	976	923	IBTK	inhibitor of Bruton tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:17853]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030292//protein tyrosine kinase inhibitor activity	GO:0001933//negative regulation of protein phosphorylation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000005801	6.123	5.249	4.64	2.886	4.588	3.319	269	244	158	106	137	125	ZNF195	zinc finger protein 195 [Source:HGNC Symbol;Acc:HGNC:12986]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000005810	5.558	3.606	3.218	2.866	3.092	3.039	1247.98	815	533	427	578.02	496	MYCBP2	MYC binding protein 2 [Source:HGNC Symbol;Acc:HGNC:23386]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K10693	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008045//motor neuron axon guidance;GO:0016567//protein ubiquitination;GO:0019222//regulation of metabolic process;GO:0021785//branchiomotor neuron axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0031398//positive regulation of protein ubiquitination;GO:0032880//regulation of protein localization;GO:0032922//circadian regulation of gene expression;GO:0042177//negative regulation of protein catabolic process;GO:0048511//rhythmic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050790//regulation of catalytic activity;GO:0050905//neuromuscular process;GO:0051493//regulation of cytoskeleton organization;GO:1902667//regulation of axon guidance	--
ENSG00000005812	12.065	9.825	9.491	8.502	9.824	10.555	839	674	461	458	566	516	FBXL3	F-box and leucine rich repeat protein 3 [Source:HGNC Symbol;Acc:HGNC:13599]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K10269	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031648//protein destabilization;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle	--
ENSG00000005844	0	0	0	0	0.099	0	0	0	0	0	1	0	ITGAL	integrin subunit alpha L [Source:HGNC Symbol;Acc:HGNC:6148]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune system;Infectious disease: viral;Cell motility;Signal transduction;Immune system;Infectious disease: bacterial;Immune disease;Signaling molecules and interaction;Cardiovascular disease;Immune system;Infectious disease: parasitic	ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05166//Human T-cell leukemia virus 1 infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko04670//Leukocyte transendothelial migration;ko05144//Malaria	K05718;K05718;K05718;K05718;K05718;K05718;K05718;K05718;K05718;K05718;K05718;K05718	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034687//integrin alphaL-beta2 complex;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0030369//ICAM-3 receptor activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0035683//memory T cell extravasation;GO:0043113//receptor clustering;GO:0098609//cell-cell adhesion	--
ENSG00000005882	29.088	29.504	30.076	35.631	33.412	27.674	1378.37	1442.09	1161.56	1252.59	1323.27	1044.7	PDK2	pyruvate dehydrogenase kinase 2 [Source:HGNC Symbol;Acc:HGNC:8810]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K00898	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005967//mitochondrial pyruvate dehydrogenase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006468//protein phosphorylation;GO:0006885//regulation of pH;GO:0008286//insulin receptor signaling pathway;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0010565//regulation of cellular ketone metabolic process;GO:0010906//regulation of glucose metabolic process;GO:0016310//phosphorylation;GO:0031670//cellular response to nutrient;GO:0034614//cellular response to reactive oxygen species;GO:0042593//glucose homeostasis;GO:0050848//regulation of calcium-mediated signaling;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000005884	60.238	66.542	55.764	70.814	78.598	65.954	5577	6041	3473	4748	6188	4361	ITGA3	integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06482;K06482;K06482;K06482;K06482;K06482;K06482;K06482;K06482;K06482;K06482	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030426//growth cone;GO:0031527//filopodium membrane;GO:0034667//integrin alpha3-beta1 complex;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0060076//excitatory synapse;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0097060//synaptic membrane;GO:1990812//growth cone filopodium	GO:0001968//fibronectin binding;GO:0002020//protease binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0019904//protein domain specific binding;GO:0043236//laminin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007507//heart development;GO:0007613//memory;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010976//positive regulation of neuron projection development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0030324//lung development;GO:0030510//regulation of BMP signaling pathway;GO:0031345//negative regulation of cell projection organization;GO:0033627//cell adhesion mediated by integrin;GO:0034698//response to gonadotropin;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035640//exploration behavior;GO:0043588//skin development;GO:0048333//mesodermal cell differentiation;GO:0050900//leukocyte migration;GO:0060135//maternal process involved in female pregnancy;GO:0072006//nephron development;GO:0097062//dendritic spine maintenance;GO:0097205//renal filtration;GO:0098609//cell-cell adhesion;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000005889	5.279	3.621	5.62	2.5	3.369	4.703	506	458	341	260	334	343	ZFX	zinc finger protein X-linked [Source:HGNC Symbol;Acc:HGNC:12869]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043035//chromatin insulator sequence binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000005893	147.918	141.742	140.125	126.337	133.06	145.66	11496	10675	7858	6917	8149	7933	LAMP2	lysosomal associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:6501]	Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Transport and catabolism;Transport and catabolism;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome;ko04140//Autophagy - animal;ko04142//Lysosome	K06528;K06528;K06528;K06528	GO:0000421//autophagosome membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031088//platelet dense granule membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0044754//autolysosome;GO:0048471//perinuclear region of cytoplasm;GO:0061742//chaperone-mediated autophagy translocation complex;GO:0070062//extracellular exosome;GO:0097637//integral component of autophagosome membrane;GO:0098857//membrane microdomain;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding	GO:0006605//protein targeting;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0017038//protein import;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031647//regulation of protein stability;GO:0046716//muscle cell cellular homeostasis;GO:0050821//protein stabilization;GO:0061684//chaperone-mediated autophagy;GO:0061740//protein targeting to lysosome involved in chaperone-mediated autophagy;GO:0072594//establishment of protein localization to organelle;GO:0097352//autophagosome maturation;GO:1905146//lysosomal protein catabolic process	--
ENSG00000005961	0.359	0.426	0.623	0.625	0.25	0.538	24	25	25	26	14	23	ITGA2B	integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Immune system;Cell motility;Signal transduction;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Cardiovascular disease;Immune system;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04613//Neutrophil extracellular trap formation;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05418//Fluid shear stress and atherosclerosis;ko04611//Platelet activation;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476;K06476	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0098609//cell-cell adhesion	--
ENSG00000005981	0	0	0	0	0	0	0	0	0	0	0	0	ASB4	ankyrin repeat and SOCS box containing 4 [Source:HGNC Symbol;Acc:HGNC:16009]	-	-	-	-	GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0051865//protein autoubiquitination;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000006007	35.947	32.79	32.616	29.407	29.855	33.396	1962	1826	1365	1179	1405	1344	GDE1	glycerophosphodiester phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:29644]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047395//glycerophosphoinositol glycerophosphodiesterase activity	GO:0006580//ethanolamine metabolic process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0070291//N-acylethanolamine metabolic process	--
ENSG00000006015	13.453	12.357	13.942	16.063	16.096	16.248	207	190	156	184	211	178	REX1BD	required for excision 1-B domain containing [Source:HGNC Symbol;Acc:HGNC:26098]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000006016	0.055	0.217	0.15	0	0.098	0	2	7	4	0	3	0	CRLF1	cytokine receptor like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0043235//receptor complex;GO:0097058//CRLF-CLCF1 complex	GO:0004896//cytokine receptor activity;GO:0005125//cytokine activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0001657//ureteric bud development;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043524//negative regulation of neuron apoptotic process;GO:2000672//negative regulation of motor neuron apoptotic process	--
ENSG00000006025	1.842	2.029	1.799	2.416	2.414	1.935	140	155	101	136	155	107	OSBPL7	oxysterol binding protein like 7 [Source:HGNC Symbol;Acc:HGNC:16387]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0010506//regulation of autophagy;GO:0015918//sterol transport;GO:0071397//cellular response to cholesterol;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000006042	1462.295	1502.379	1686.106	2018.529	1853.446	2100.02	45655	46555	38709	46735	48651	48263	TMEM98	transmembrane protein 98 [Source:HGNC Symbol;Acc:HGNC:24529]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0010955//negative regulation of protein processing;GO:0031642//negative regulation of myelination;GO:0045063//T-helper 1 cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000006047	0.962	0.725	0.908	0.669	0.759	1.162	33	25	23	17	22	29	YBX2	Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding	GO:0006366//transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0009386//translational attenuation;GO:0010468//regulation of gene expression;GO:0048599//oocyte development;GO:0120162//positive regulation of cold-induced thermogenesis	CSD
ENSG00000006059	0	0	0	0	0	0	0	0	0	0	0	0	KRT33A	keratin 33A [Source:HGNC Symbol;Acc:HGNC:6450]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000006062	1.381	1.026	1.043	0.733	1.227	1.42	124	95	71	48	93	86	MAP3K14	mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Signal transduction;Endocrine and metabolic disease;Cell growth and death;Development and regeneration;Immune system;Signal transduction;Immune system;Immune system;Infectious disease: bacterial	ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04064//NF-kappa B signaling pathway;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04380//Osteoclast differentiation;ko04672//Intestinal immune network for IgA production;ko04668//TNF signaling pathway;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466;K04466	GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016310//phosphorylation;GO:0038061//NIK/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051607//defense response to virus;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000006071	0	0	0	0.026	0	0	0	0	0	1	0	0	ABCC8	ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]	Organismal Systems;Human Diseases;Environmental Information Processing	Endocrine system;Endocrine and metabolic disease;Membrane transport	ko04911//Insulin secretion;ko04930//Type II diabetes mellitus;ko02010//ABC transporters	K05032;K05032;K05032	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0008282//inward rectifying potassium channel;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030672//synaptic vesicle membrane;GO:0031004//potassium ion-transporting ATPase complex;GO:0042383//sarcolemma	GO:0000166//nucleotide binding;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008281//sulfonylurea receptor activity;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0044325//transmembrane transporter binding;GO:0140359//ABC-type transporter activity	GO:0001678//cellular glucose homeostasis;GO:0006813//potassium ion transport;GO:0007565//female pregnancy;GO:0007613//memory;GO:0008542//visual learning;GO:0009268//response to pH;GO:0009410//response to xenobiotic stimulus;GO:0010043//response to zinc ion;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0016525//negative regulation of angiogenesis;GO:0032496//response to lipopolysaccharide;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032868//response to insulin;GO:0043268//positive regulation of potassium ion transport;GO:0046676//negative regulation of insulin secretion;GO:0050768//negative regulation of neurogenesis;GO:0055085//transmembrane transport;GO:0060253//negative regulation of glial cell proliferation;GO:0061045//negative regulation of wound healing;GO:0061855//negative regulation of neuroblast migration;GO:0071310//cellular response to organic substance;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:1900721//positive regulation of uterine smooth muscle relaxation;GO:1903818//positive regulation of voltage-gated potassium channel activity;GO:1905075//positive regulation of tight junction disassembly;GO:1905604//negative regulation of blood-brain barrier permeability;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000006116	0	0	0	0	0	0	0	0	0	0	0	0	CACNG3	calcium voltage-gated channel auxiliary subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:1407]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04868;K04868;K04868;K04868;K04868;K04868;K04868	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0036477//somatodendritic compartment;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity;GO:0030165//PDZ domain binding;GO:0035255//ionotropic glutamate receptor binding	"GO:0006605//protein targeting;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0008104//protein localization;GO:0019226//transmission of nerve impulse;GO:0034765//regulation of ion transmembrane transport;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099590//neurotransmitter receptor internalization;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane;GO:2000311//regulation of AMPA receptor activity;GO:2000969//positive regulation of AMPA receptor activity"	--
ENSG00000006118	228.96	245.738	248.973	216.936	238.015	213.553	15796	16714	12374	11253	13737	10706	TMEM132A	transmembrane protein 132A [Source:HGNC Symbol;Acc:HGNC:31092]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000006125	77.474	82.991	81.239	74.215	76.461	70.16	8886	9390	6896	6373	7458	5902	AP2B1	adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563]	Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K11825;K11825;K11825;K11825	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030118//clathrin coat;GO:0030122//AP-2 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0036020//endolysosome membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0097708//intracellular vesicle;GO:0098588//bounding membrane of organelle;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0030276//clathrin binding;GO:0035615//clathrin adaptor activity;GO:0044877//protein-containing complex binding	GO:0001822//kidney development;GO:0003279//cardiac septum development;GO:0003281//ventricular septum development;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007507//heart development;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0035904//aorta development;GO:0045807//positive regulation of endocytosis;GO:0048268//clathrin coat assembly;GO:0060976//coronary vasculature development;GO:0072583//clathrin-dependent endocytosis;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:0099590//neurotransmitter receptor internalization;GO:1901215//negative regulation of neuron death;GO:1905477//positive regulation of protein localization to membrane	--
ENSG00000006128	0	0	0	0	0.059	0.068	0	0	0	0	1	1	TAC1	tachykinin precursor 1 [Source:HGNC Symbol;Acc:HGNC:11517]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05239	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0031835//substance P receptor binding	GO:0006954//inflammatory response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007217//tachykinin receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007320//insemination;GO:0009582//detection of abiotic stimulus;GO:0019233//sensory perception of pain;GO:0048265//response to pain;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000006194	15.68	15.316	15.451	14.746	15.437	16.25	599.73	557.3	499.09	444.97	572.08	501.87	ZNF263	zinc finger protein 263 [Source:HGNC Symbol;Acc:HGNC:13056]	-	-	-	-	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000006210	0.895	1.3	0.934	1.643	1.042	0.886	61	89	47	83	60	44	CX3CL1	C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647]	Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Immune system;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko04062//Chemokine signaling pathway;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05508;K05508;K05508;K05508;K05508	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031737//CX3C chemokine receptor binding;GO:0042056//chemoattractant activity;GO:0045237//CXCR1 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0001774//microglial cell activation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002052//positive regulation of neuroblast proliferation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002548//monocyte chemotaxis;GO:0002931//response to ischemia;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0010976//positive regulation of neuron projection development;GO:0016322//neuron remodeling;GO:0019221//cytokine-mediated signaling pathway;GO:0030336//negative regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032690//negative regulation of interleukin-1 alpha production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0033622//integrin activation;GO:0035425//autocrine signaling;GO:0042060//wound healing;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0043547//positive regulation of GTPase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0050767//regulation of neurogenesis;GO:0050902//leukocyte adhesive activation;GO:0050918//positive chemotaxis;GO:0051041//positive regulation of calcium-independent cell-cell adhesion;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051897//positive regulation of protein kinase B signaling;GO:0060055//angiogenesis involved in wound healing;GO:0060326//cell chemotaxis;GO:0061518//microglial cell proliferation;GO:0070050//neuron cellular homeostasis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0098609//cell-cell adhesion;GO:0098883//synapse pruning;GO:0110091//negative regulation of hippocampal neuron apoptotic process;GO:1900450//negative regulation of glutamate receptor signaling pathway;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1903979//negative regulation of microglial cell activation;GO:1904141//positive regulation of microglial cell migration;GO:2001223//negative regulation of neuron migration;GO:2001234//negative regulation of apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000006282	73.496	68.558	75.712	73.287	75.471	70.973	3070	3288	2437	2401	2721	2054	SPATA20	spermatogenesis associated 20 [Source:HGNC Symbol;Acc:HGNC:26125]	-	-	-	-	GO:0005576//extracellular region	-	GO:0005975//carbohydrate metabolic process;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000006283	0.052	0.006	0.05	0	0	0.014	2	1	2	0	0	1	CACNA1G	calcium voltage-gated channel subunit alpha1 G [Source:HGNC Symbol;Acc:HGNC:1394]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Endocrine system;Endocrine system;Endocrine and metabolic disease	ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04934//Cushing syndrome;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04930//Type II diabetes mellitus	K04854;K04854;K04854;K04854;K04854;K04854;K04854;K04854	GO:0001518//voltage-gated sodium channel complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0008332//low voltage-gated calcium channel activity;GO:0086056//voltage-gated calcium channel activity involved in AV node cell action potential;GO:0086059//voltage-gated calcium channel activity involved SA node cell action potential;GO:0097110//scaffold protein binding	GO:0001508//action potential;GO:0002027//regulation of heart rate;GO:0003163//sinoatrial node development;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0010045//response to nickel cation;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0055085//transmembrane transport;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086010//membrane depolarization during action potential;GO:0086015//SA node cell action potential;GO:0086016//AV node cell action potential;GO:0086018//SA node cell to atrial cardiac muscle cell signaling;GO:0086027//AV node cell to bundle of His cell signaling;GO:0086045//membrane depolarization during AV node cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098655//cation transmembrane transport	--
ENSG00000006327	15.84	15.618	14.175	13.19	11.533	11.635	321	315	212	198	196	171	TNFRSF12A	TNF receptor superfamily member 12A [Source:HGNC Symbol;Acc:HGNC:18152]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05149	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0030154//cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0061041//regulation of wound healing;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000006377	0	0	0.028	0	0	0	0	0	1	0	0	0	DLX6	distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGNC:2919]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030855//epithelial cell differentiation;GO:0042472//inner ear morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060322//head development"	Homeobox
ENSG00000006432	4.547	4.279	4.394	4.047	4.221	3.877	952	878	679	605	680	592	MAP3K9	mitogen-activated protein kinase kinase kinase 9 [Source:HGNC Symbol;Acc:HGNC:6861]	Environmental Information Processing;Organismal Systems	Signal transduction;Development and regeneration	ko04013//MAPK signaling pathway - fly;ko04361//Axon regeneration	K04417;K04417	GO:0005575//cellular_component	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0008219//cell death;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0046777//protein autophosphorylation	--
ENSG00000006451	13.441	13.149	13.834	11.023	11.569	12.458	777	764	581	472	565	524	RALA	RAS like proto-oncogene A [Source:HGNC Symbol;Acc:HGNC:9839]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: bacterial;Signal transduction;Signal transduction;Signal transduction;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer	K07834;K07834;K07834;K07834;K07834;K07834;K07834	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0032154//cleavage furrow;GO:0070062//extracellular exosome;GO:0090543//Flemming body	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0017022//myosin binding;GO:0019003//GDP binding;GO:0031625//ubiquitin protein ligase binding;GO:0031755//Edg-2 lysophosphatidic acid receptor binding;GO:0051117//ATPase binding	GO:0001843//neural tube closure;GO:0006887//exocytosis;GO:0006935//chemotaxis;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0017157//regulation of exocytosis;GO:0031532//actin cytoskeleton reorganization;GO:0051301//cell division;GO:0051491//positive regulation of filopodium assembly;GO:0051665//membrane raft localization;GO:0072655//establishment of protein localization to mitochondrion;GO:0090141//positive regulation of mitochondrial fission	--
ENSG00000006453	6.851	7.313	5.806	4.822	5.542	5.718	517.98	555.74	324.22	270.04	354	314.53	BAIAP2L1	BAR/IMD domain containing adaptor protein 2 like 1 [Source:HGNC Symbol;Acc:HGNC:21649]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K20127	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0070064//proline-rich region binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0007009//plasma membrane organization;GO:0009617//response to bacterium;GO:0030833//regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0046626//regulation of insulin receptor signaling pathway;GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0098609//cell-cell adhesion;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000006459	1.286	1.194	0.949	0.854	1.04	0.906	246	226	134	121	168	126	KDM7A	lysine demethylase 7A [Source:HGNC Symbol;Acc:HGNC:22224]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003712//transcription coregulator activity;GO:0005506//iron ion binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0035064//methylated histone binding;GO:0035575//histone H4-methyl-lysine-20 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0071558//histone H3-tri/di-methyl-lysine-27 demethylase activity;GO:0140683//histone H3-di/monomethyl-lysine-9 demethylase activity	"GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0007399//nervous system development;GO:0030901//midbrain development;GO:0033169//histone H3-K9 demethylation;GO:0035574//histone H4-K20 demethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0071557//histone H3-K27 demethylation"	--
ENSG00000006468	2.146	1.579	1.354	1.766	2.203	1.632	158	128	53	81	139	105	ETV1	ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09431	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007411//axon guidance;GO:0007517//muscle organ development;GO:0007638//mechanosensory behavior;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048935//peripheral nervous system neuron development"	ETS
ENSG00000006530	11.076	12.43	12.377	10.95	11.079	13.41	559	573	479	420	455	478	AGK	acylglycerol kinase [Source:HGNC Symbol;Acc:HGNC:21869]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism	K09881;K09881	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016020//membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001727//lipid kinase activity;GO:0001729//ceramide kinase activity;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0047620//acylglycerol kinase activity;GO:0102773//dihydroceramide kinase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0016310//phosphorylation;GO:0045039//protein insertion into mitochondrial inner membrane;GO:0046486//glycerolipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0046834//lipid phosphorylation	--
ENSG00000006534	22.414	24.216	27.198	43.212	38.318	29.753	1155	1272	1018	1635	1711	1130	ALDH3B1	aldehyde dehydrogenase 3 family member B1 [Source:HGNC Symbol;Acc:HGNC:410]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Xenobiotics biodegradation and metabolism;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00982//Drug metabolism - cytochrome P450;ko00350//Tyrosine metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism;ko00360//Phenylalanine metabolism	K00129;K00129;K00129;K00129;K00129;K00129;K00129;K00129	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031982//vesicle;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	"GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0018477//benzaldehyde dehydrogenase (NADP+) activity;GO:0018479//benzaldehyde dehydrogenase (NAD+) activity;GO:0033721//aldehyde dehydrogenase (NADP+) activity"	GO:0006066//alcohol metabolic process;GO:0006068//ethanol catabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0006979//response to oxidative stress;GO:0030148//sphingolipid biosynthetic process;GO:0034599//cellular response to oxidative stress;GO:0046185//aldehyde catabolic process	--
ENSG00000006555	0.156	0.24	0.345	0.413	0.117	0.261	11	17	18	10	7	12	TTC22	tetratricopeptide repeat domain 22 [Source:HGNC Symbol;Acc:HGNC:26067]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000006576	17.201	13.341	9.846	8.81	9.734	11.861	1682	1297	725	624	803	794	PHTF2	putative homeodomain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:13411]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000006606	0.101	0.101	0.137	0	0.12	0	1	1	1	0	1	0	CCL26	C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21096;K21096;K21096	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031728//CCR3 chemokine receptor binding;GO:0031737//CX3C chemokine receptor binding;GO:0048018//receptor ligand activity;GO:0048020//CCR chemokine receptor binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010818//T cell chemotaxis;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0043547//positive regulation of GTPase activity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050921//positive regulation of chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000006607	8.015	8.452	9.489	7.675	9.068	7.721	697.89	765.73	594.68	506.95	638.34	505.91	FARP2	"FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:HGNC Symbol;Acc:HGNC:16460]"	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04015//Rap1 signaling pathway;ko04520//Adherens junction	K06082;K06082	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008092//cytoskeletal protein binding	GO:0007155//cell adhesion;GO:0016322//neuron remodeling;GO:0016601//Rac protein signal transduction;GO:0022405//hair cycle process;GO:0030316//osteoclast differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0033623//regulation of integrin activation;GO:0050790//regulation of catalytic activity;GO:0071526//semaphorin-plexin signaling pathway;GO:0071800//podosome assembly	--
ENSG00000006611	0.067	0.064	0	0.091	0.118	0.237	3	3	0	3	3	8	USH1C	USH1 protein network component harmonin [Source:HGNC Symbol;Acc:HGNC:12597]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0002142//stereocilia ankle link complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0005929//cilium;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0045202//synapse	GO:0005515//protein binding;GO:0030507//spectrin binding;GO:0051015//actin filament binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0007605//sensory perception of sound;GO:0030046//parallel actin filament bundle assembly;GO:0030154//cell differentiation;GO:0032532//regulation of microvillus length;GO:0034622//cellular protein-containing complex assembly;GO:0042472//inner ear morphogenesis;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0046549//retinal cone cell development;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0051017//actin filament bundle assembly;GO:0060122//inner ear receptor cell stereocilium organization;GO:1904106//protein localization to microvillus;GO:1904970//brush border assembly	--
ENSG00000006625	13.009	13.775	14.93	15.326	12.604	15.752	295	326.53	260	263	249	270	GGCT	gamma-glutamylcyclotransferase [Source:HGNC Symbol;Acc:HGNC:21705]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K00682;K00682	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003839//gamma-glutamylcyclotransferase activity;GO:0016829//lyase activity;GO:0042803//protein homodimerization activity	GO:0001836//release of cytochrome c from mitochondria	--
ENSG00000006634	2.331	2.322	2.478	1.483	1.809	2.786	123	125	94	60	83	107	DBF4	DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06629	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0031431//Dbf4-dependent protein kinase complex;GO:0043229//intracellular organelle	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008270//zinc ion binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0050790//regulation of catalytic activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1901987//regulation of cell cycle phase transition	--
ENSG00000006638	0.522	0.672	0.469	0.542	0.346	0.192	23	37	19	22	16	6	TBXA2R	thromboxane A2 receptor [Source:HGNC Symbol;Acc:HGNC:11608]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04611//Platelet activation	K04264;K04264;K04264	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0004930//G protein-coupled receptor activity;GO:0004960//thromboxane receptor activity;GO:0004961//thromboxane A2 receptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0019229//regulation of vasoconstriction;GO:0019932//second-messenger-mediated signaling;GO:0030194//positive regulation of blood coagulation;GO:0032496//response to lipopolysaccharide;GO:0033574//response to testosterone;GO:0038193//thromboxane A2 signaling pathway;GO:0045471//response to ethanol;GO:0045766//positive regulation of angiogenesis;GO:0045777//positive regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0045987//positive regulation of smooth muscle contraction;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus;GO:0071222//cellular response to lipopolysaccharide;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis	--
ENSG00000006652	13.38	13.923	12.312	8.516	9.531	15.496	696.08	674.12	472.9	290.58	375.92	559.82	IFRD1	interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456]	-	-	-	-	GO:0005634//nucleus	-	GO:0007518//myoblast fate determination;GO:0030154//cell differentiation	--
ENSG00000006659	0	0	0	0	0	0	0	0	0	0	0	0	LGALS14	galectin 14 [Source:HGNC Symbol;Acc:HGNC:30054]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006915//apoptotic process;GO:0070234//positive regulation of T cell apoptotic process	--
ENSG00000006695	5.394	4.174	4.984	6.842	6.027	5.834	304	245	183	213	264	215	COX10	cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 [Source:HGNC Symbol;Acc:HGNC:2260]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation;ko00860//Porphyrin metabolism	K02257;K02257;K02257;K02257	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070069//cytochrome complex	"GO:0004311//farnesyltranstransferase activity;GO:0008495//protoheme IX farnesyltransferase activity;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups"	GO:0000266//mitochondrial fission;GO:0006629//lipid metabolic process;GO:0006783//heme biosynthetic process;GO:0006784//heme A biosynthetic process;GO:0007005//mitochondrion organization;GO:0008535//respiratory chain complex IV assembly;GO:0009060//aerobic respiration;GO:0017004//cytochrome complex assembly	--
ENSG00000006704	29.273	30.672	32.238	28.237	32.564	29.59	2029	2016	1502	1338	1578	1495	GTF2IRD1	GTF2I repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:4661]	Environmental Information Processing;Genetic Information Processing	Signal transduction;Transcription	ko04022//cGMP-PKG signaling pathway;ko03022//Basal transcription factors	K03121;K03121	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0014886//transition between slow and fast fiber"	GTF2I
ENSG00000006712	33.215	32.835	33.957	32.527	33.476	29.349	1505	1496	1139	1093	1285	968	PAF1	"PAF1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:25459]"	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016593//Cdc73/Paf1 complex;GO:0030054//cell junction	GO:0000993//RNA polymerase II complex binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001711//endodermal cell fate commitment;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006378//mRNA polyadenylation;GO:0010390//histone monoubiquitination;GO:0016055//Wnt signaling pathway;GO:0016570//histone modification;GO:0016584//nucleosome positioning;GO:0019827//stem cell population maintenance;GO:0031062//positive regulation of histone methylation;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0033523//histone H2B ubiquitination;GO:0034504//protein localization to nucleus;GO:0045638//negative regulation of myeloid cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000006715	58.425	53.565	50.811	45.988	51.746	52.016	3342	3025	2225	2039	2505	2227	VPS41	VPS41 subunit of HOPS complex [Source:HGNC Symbol;Acc:HGNC:12713]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20184	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030897//HOPS complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0071439//clathrin complex;GO:1902501//lysosomal HOPS complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006623//protein targeting to vacuole;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0009267//cellular response to starvation;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016236//macroautophagy;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly;GO:0046907//intracellular transport;GO:0048193//Golgi vesicle transport;GO:1902774//late endosome to lysosome transport	--
ENSG00000006740	3.358	2.845	3.206	3.453	3.401	4.024	279	250	207	223	248	255	ARHGAP44	Rho GTPase activating protein 44 [Source:HGNC Symbol;Acc:HGNC:29096]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031256//leading edge membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0055037//recycling endosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0031267//small GTPase binding	"GO:0006887//exocytosis;GO:0007165//signal transduction;GO:0032956//regulation of actin cytoskeleton organization;GO:0035020//regulation of Rac protein signal transduction;GO:0035021//negative regulation of Rac protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051490//negative regulation of filopodium assembly;GO:0061001//regulation of dendritic spine morphogenesis;GO:0098886//modification of dendritic spine;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099010//modification of postsynaptic structure;GO:0099152//regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane"	--
ENSG00000006744	16.842	20.337	19.43	19.816	19.387	17.387	1035	1202	889	863	913	808	ELAC2	elaC ribonuclease Z 2 [Source:HGNC Symbol;Acc:HGNC:14198]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0042645//mitochondrial nucleoid	GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004549//tRNA-specific ribonuclease activity;GO:0016787//hydrolase activity;GO:0042781//3'-tRNA processing endoribonuclease activity;GO:0046872//metal ion binding	"GO:0008033//tRNA processing;GO:0016078//tRNA catabolic process;GO:0034414//tRNA 3'-trailer cleavage, endonucleolytic;GO:0042780//tRNA 3'-end processing;GO:0072684//mitochondrial tRNA 3'-trailer cleavage, endonucleolytic;GO:0090646//mitochondrial tRNA processing"	--
ENSG00000006747	6.336	6.067	5.019	10.556	9.433	8.873	342	348	208	463	485	377	SCIN	scinderin [Source:HGNC Symbol;Acc:HGNC:21695]	Cellular Processes;Human Diseases;Organismal Systems	Cell motility;Cancer: overview;Immune system	ko04810//Regulation of actin cytoskeleton;ko05203//Viral carcinogenesis;ko04666//Fc gamma R-mediated phagocytosis	K05768;K05768;K05768	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005903//brush border;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0042995//cell projection;GO:0070062//extracellular exosome	"GO:0001786//phosphatidylserine binding;GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005545//1-phosphatidylinositol binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding"	GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0008285//negative regulation of cell population proliferation;GO:0017156//calcium-ion regulated exocytosis;GO:0030031//cell projection assembly;GO:0032330//regulation of chondrocyte differentiation;GO:0042989//sequestering of actin monomers;GO:0043065//positive regulation of apoptotic process;GO:0045010//actin nucleation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051047//positive regulation of secretion;GO:0051127//positive regulation of actin nucleation;GO:0051693//actin filament capping	--
ENSG00000006756	9.848	11.01	10.594	11.691	11.014	8.5	1051	1181	835	905	993	660	ARSD	arylsulfatase D [Source:HGNC Symbol;Acc:HGNC:717]	-	-	-	-	GO:0005764//lysosome;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000006757	14.4	16.107	13.187	10.765	17.239	14.134	516	491	351	353	440	358	PNPLA4	patatin like phospholipase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24887]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11157;K11157	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane	"GO:0004806//triglyceride lipase activity;GO:0016787//hydrolase activity;GO:0047376//all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0050253//retinyl-palmitate esterase activity"	GO:0006629//lipid metabolic process;GO:0008150//biological_process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0042572//retinol metabolic process;GO:0055088//lipid homeostasis	--
ENSG00000006788	0.008	0	0.014	0	0.01	0	1	0	1.25	0	1	0	MYH13	myosin heavy chain 13 [Source:HGNC Symbol;Acc:HGNC:7571]	-	-	-	-	GO:0005737//cytoplasm;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0032982//myosin filament;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0009267//cellular response to starvation	--
ENSG00000006831	50.567	49.028	52.652	42.926	44.764	47.338	4165	4059	3203	2619	3115	2837	ADIPOR2	adiponectin receptor 2 [Source:HGNC Symbol;Acc:HGNC:24041]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine and metabolic disease;Signal transduction;Aging;Endocrine system	ko04932//Non-alcoholic fatty liver disease;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway	K07297;K07297;K07297;K07297;K07297	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0055100//adiponectin binding;GO:0097003//adipokinetic hormone receptor activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0019395//fatty acid oxidation;GO:0033211//adiponectin-activated signaling pathway;GO:0042593//glucose homeostasis;GO:0061042//vascular wound healing;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000006837	0.917	0.925	1.444	0.629	0.5	0.851	23	27	22	17	12	15	CDKL3	cyclin dependent kinase like 3 [Source:HGNC Symbol;Acc:HGNC:15483]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030517//negative regulation of axon extension;GO:0050775//positive regulation of dendrite morphogenesis;GO:0051726//regulation of cell cycle;GO:0097484//dendrite extension	--
ENSG00000007001	0	0	0	0	0	0	0	0	0	0	0	0	UPP2	uridine phosphorylase 2 [Source:HGNC Symbol;Acc:HGNC:23061]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00757;K00757;K00757	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045098//type III intermediate filament	GO:0003824//catalytic activity;GO:0004850//uridine phosphorylase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042802//identical protein binding;GO:0047847//deoxyuridine phosphorylase activity	GO:0006218//uridine catabolic process;GO:0006249//dCMP catabolic process;GO:0009116//nucleoside metabolic process;GO:0009164//nucleoside catabolic process;GO:0009166//nucleotide catabolic process;GO:0044206//UMP salvage;GO:0046108//uridine metabolic process	--
ENSG00000007038	0	0	0	0	0	0	0	0	0	0	0	0	PRSS21	serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007283//spermatogenesis	--
ENSG00000007047	15.36	17.773	21.991	21.13	19.207	19.647	1213	1310	924	1058	1082	984	MARK4	microtubule affinity regulating kinase 4 [Source:HGNC Symbol;Acc:HGNC:13538]	-	-	-	-	GO:0000930//gamma-tubulin complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0030425//dendrite;GO:0030496//midbody;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043015//gamma-tubulin binding;GO:0043130//ubiquitin binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0035556//intracellular signal transduction;GO:0043068//positive regulation of programmed cell death;GO:0044782//cilium organization;GO:0045724//positive regulation of cilium assembly;GO:0045787//positive regulation of cell cycle;GO:0046605//regulation of centrosome cycle;GO:0051301//cell division;GO:1904781//positive regulation of protein localization to centrosome	--
ENSG00000007062	6.287	6.197	7.48	5.279	4.336	4.679	510	458	358	255	267	286	PROM1	prominin 1 [Source:HGNC Symbol;Acc:HGNC:9454]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K06532	GO:0001750//photoreceptor outer segment;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0071914//prominosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0042805//actinin binding;GO:0045296//cadherin binding	GO:0010842//retina layer formation;GO:0045494//photoreceptor cell maintenance;GO:0060042//retina morphogenesis in camera-type eye;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072139//glomerular parietal epithelial cell differentiation;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation	--
ENSG00000007080	50.064	58.912	52.137	63.687	55.269	57.382	1018	1210	779	966	952	855	CCDC124	coiled-coil domain containing 124 [Source:HGNC Symbol;Acc:HGNC:25171]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030496//midbody	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding	"GO:0006366//transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division"	--
ENSG00000007129	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM21	CEA cell adhesion molecule 21 [Source:HGNC Symbol;Acc:HGNC:28834]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000007168	37.196	33.193	35.706	29.91	31.741	34.443	4129	3525	2824	2411	2933	2811	PAFAH1B1	platelet activating factor acetylhydrolase 1b regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8574]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K16794;K16794	GO:0000235//astral microtubule;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005881//cytoplasmic microtubule;GO:0005938//cell cortex;GO:0008247//1-alkyl-2-acetylglycerophosphocholine esterase complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0031514//motile cilium;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0090724//central region of growth cone;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008201//heparin binding;GO:0034452//dynactin binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0044877//protein-containing complex binding;GO:0045505//dynein intermediate chain binding;GO:0046982//protein heterodimerization activity;GO:0051010//microtubule plus-end binding;GO:0051219//phosphoprotein binding;GO:0070840//dynein complex binding	GO:0000132//establishment of mitotic spindle orientation;GO:0000226//microtubule cytoskeleton organization;GO:0001667//ameboidal-type cell migration;GO:0001675//acrosome assembly;GO:0001764//neuron migration;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006629//lipid metabolic process;GO:0007017//microtubule-based process;GO:0007049//cell cycle;GO:0007097//nuclear migration;GO:0007268//chemical synaptic transmission;GO:0007281//germ cell development;GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0007420//brain development;GO:0007611//learning or memory;GO:0008090//retrograde axonal transport;GO:0008344//adult locomotory behavior;GO:0009306//protein secretion;GO:0010977//negative regulation of neuron projection development;GO:0016042//lipid catabolic process;GO:0016477//cell migration;GO:0017145//stem cell division;GO:0019226//transmission of nerve impulse;GO:0021540//corpus callosum morphogenesis;GO:0021766//hippocampus development;GO:0021819//layer formation in cerebral cortex;GO:0021895//cerebral cortex neuron differentiation;GO:0021987//cerebral cortex development;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0031023//microtubule organizing center organization;GO:0036035//osteoclast development;GO:0038026//reelin-mediated signaling pathway;GO:0040019//positive regulation of embryonic development;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0043087//regulation of GTPase activity;GO:0043622//cortical microtubule organization;GO:0045773//positive regulation of axon extension;GO:0045931//positive regulation of mitotic cell cycle;GO:0046329//negative regulation of JNK cascade;GO:0046469//platelet activating factor metabolic process;GO:0047496//vesicle transport along microtubule;GO:0048854//brain morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0051012//microtubule sliding;GO:0051081//nuclear membrane disassembly;GO:0051130//positive regulation of cellular component organization;GO:0051301//cell division;GO:0051660//establishment of centrosome localization;GO:0051661//maintenance of centrosome location;GO:0060117//auditory receptor cell development;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0090102//cochlea development;GO:0090176//microtubule cytoskeleton organization involved in establishment of planar polarity	--
ENSG00000007171	0.088	0.16	0.215	0.326	0.086	0.265	7	14	11	20	6	16	NOS2	nitric oxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:7873]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: bacterial;Infectious disease: parasitic;Infectious disease: parasitic;Signal transduction;Endocrine system;Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Transport and catabolism;Infectious disease: bacterial;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko05152//Tuberculosis;ko05146//Amoebiasis;ko05140//Leishmaniasis;ko04371//Apelin signaling pathway;ko04926//Relaxin signaling pathway;ko04066//HIF-1 signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko05222//Small cell lung cancer;ko04146//Peroxisome;ko05133//Pertussis;ko00330//Arginine and proline metabolism;ko00220//Arginine biosynthesis	K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241;K13241	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0030863//cortical cytoskeleton;GO:0048471//perinuclear region of cytoplasm	GO:0004517//nitric-oxide synthase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0034617//tetrahydrobiopterin binding;GO:0034618//arginine binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding	GO:0001666//response to hypoxia;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002227//innate immune response in mucosa;GO:0006527//arginine catabolic process;GO:0006801//superoxide metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0006954//inflammatory response;GO:0007263//nitric oxide mediated signal transduction;GO:0007623//circadian rhythm;GO:0009617//response to bacterium;GO:0009725//response to hormone;GO:0010629//negative regulation of gene expression;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0031284//positive regulation of guanylate cyclase activity;GO:0032310//prostaglandin secretion;GO:0032496//response to lipopolysaccharide;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0042127//regulation of cell population proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0042742//defense response to bacterium;GO:0043457//regulation of cellular respiration;GO:0044249//cellular biosynthetic process;GO:0045454//cell redox homeostasis;GO:0045776//negative regulation of blood pressure;GO:0050796//regulation of insulin secretion;GO:0050829//defense response to Gram-negative bacterium;GO:0051712//positive regulation of killing of cells of other organism;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071466//cellular response to xenobiotic stimulus;GO:1900015//regulation of cytokine production involved in inflammatory response	--
ENSG00000007174	1.041	1.252	1.249	0.453	0.451	0.367	130	180	87	45	46	26	DNAH9	dynein axonemal heavy chain 9 [Source:HGNC Symbol;Acc:HGNC:2953]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0097729//9+2 motile cilium;GO:0120135//distal portion of axoneme	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0030030//cell projection organization;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance	--
ENSG00000007202	55.527	57.177	57.385	56.489	56.357	58.303	8337	8463	6388	6337	7144	6152	KIAA0100	KIAA0100 [Source:HGNC Symbol;Acc:HGNC:28960]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000007216	0.593	0.511	0.914	0.609	0.642	0.525	30	26	36	26	30	20	SLC13A2	solute carrier family 13 member 2 [Source:HGNC Symbol;Acc:HGNC:10917]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015141//succinate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015361//low-affinity sodium:dicarboxylate symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:0071422//succinate transmembrane transport;GO:0098656//anion transmembrane transport	--
ENSG00000007237	23.005	24.099	18.826	11.348	13.235	10.486	3346	3655	2156	1348	1847	1270	GAS7	growth arrest specific 7 [Source:HGNC Symbol;Acc:HGNC:4169]	-	-	-	-	GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051015//actin filament binding	GO:0007399//nervous system development;GO:0030041//actin filament polymerization;GO:0030154//cell differentiation;GO:0048812//neuron projection morphogenesis	--
ENSG00000007255	5.721	8.882	9.399	10.878	9.898	7.912	85	129	102	124	119	88	TRAPPC6A	trafficking protein particle complex subunit 6A [Source:HGNC Symbol;Acc:HGNC:23069]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0043087//regulation of GTPase activity;GO:0043473//pigmentation;GO:0048193//Golgi vesicle transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering;GO:1903232//melanosome assembly	--
ENSG00000007264	0	0	0	0	0	0.172	0	0	0	0	0	2	MATK	megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K08888	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation	--
ENSG00000007306	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM7	CEA cell adhesion molecule 7 [Source:HGNC Symbol;Acc:HGNC:1819]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane	-	-	--
ENSG00000007312	1.976	1.694	0.943	1.933	1.237	1.649	41	44	18	37	27	31	CD79B	CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699]	Organismal Systems	Immune system	ko04662//B cell receptor signaling pathway	K06507	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019815//B cell receptor complex;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030183//B cell differentiation;GO:0050853//B cell receptor signaling pathway	--
ENSG00000007314	0.012	0.006	0	0	0.015	0.025	2	1	0	0	2	3	SCN4A	sodium voltage-gated channel alpha subunit 4 [Source:HGNC Symbol;Acc:HGNC:10591]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006936//muscle contraction;GO:0019228//neuronal action potential;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0100001//regulation of skeletal muscle contraction by action potential	--
ENSG00000007341	5.27	5.253	4.151	5.116	4.968	6.142	368.4	341.31	241.58	235.15	246.91	307.59	ST7L	suppression of tumorigenicity 7 like [Source:HGNC Symbol;Acc:HGNC:18441]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030308//negative regulation of cell growth	--
ENSG00000007350	0.019	0.019	0	0	0	0	1	1	0	0	0	0	TKTL1	transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00615;K00615;K00615;K00615	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004802//transketolase activity;GO:0016740//transferase activity;GO:0030976//thiamine pyrophosphate binding;GO:0046872//metal ion binding	GO:0006007//glucose catabolic process;GO:0006772//thiamine metabolic process	--
ENSG00000007372	26.77	23.427	24.123	32.809	32.464	34.554	1148.68	1040.83	794.9	1072.31	1235.23	1108.1	PAX6	paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620]	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Endocrine and metabolic disease	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04950//Maturity onset diabetes of the young	K08031;K08031	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035035//histone acetyltransferase binding;GO:0043565//sequence-specific DNA binding;GO:0070410//co-SMAD binding;GO:0070412//R-SMAD binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000132//establishment of mitotic spindle orientation;GO:0001568//blood vessel development;GO:0001654//eye development;GO:0001709//cell fate determination;GO:0001764//neuron migration;GO:0001933//negative regulation of protein phosphorylation;GO:0002052//positive regulation of neuroblast proliferation;GO:0002088//lens development in camera-type eye;GO:0003002//regionalization;GO:0003309//type B pancreatic cell differentiation;GO:0003322//pancreatic A cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007435//salivary gland morphogenesis;GO:0007601//visual perception;GO:0008285//negative regulation of cell population proliferation;GO:0009611//response to wounding;GO:0009786//regulation of asymmetric cell division;GO:0009887//animal organ morphogenesis;GO:0009950//dorsal/ventral axis specification;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0021517//ventral spinal cord development;GO:0021543//pallium development;GO:0021778//oligodendrocyte cell fate specification;GO:0021796//cerebral cortex regionalization;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0021905//forebrain-midbrain boundary formation;GO:0021978//telencephalon regionalization;GO:0021983//pituitary gland development;GO:0021986//habenula development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030334//regulation of cell migration;GO:0030858//positive regulation of epithelial cell differentiation;GO:0030900//forebrain development;GO:0032808//lacrimal gland development;GO:0033365//protein localization to organelle;GO:0042462//eye photoreceptor cell development;GO:0042593//glucose homeostasis;GO:0043010//camera-type eye development;GO:0045165//cell fate commitment;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048505//regulation of timing of cell differentiation;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048663//neuron fate commitment;GO:0048708//astrocyte differentiation;GO:0048856//anatomical structure development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050767//regulation of neurogenesis;GO:0050768//negative regulation of neurogenesis;GO:0060041//retina development in camera-type eye;GO:0061072//iris morphogenesis;GO:0061303//cornea development in camera-type eye;GO:1904798//positive regulation of core promoter binding;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000178//negative regulation of neural precursor cell proliferation"	PAX
ENSG00000007376	7.027	7.809	9.095	10.742	11.254	12.26	235	293	258	291	320	289	RPUSD1	RNA pseudouridine synthase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14173]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity	GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0008150//biological_process;GO:0009451//RNA modification	--
ENSG00000007384	5.462	5.538	5.565	6.396	5.359	5.867	339	332	244	265	281	251	RHBDF1	rhomboid 5 homolog 1 [Source:HGNC Symbol;Acc:HGNC:20561]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0019838//growth factor binding	GO:0006508//proteolysis;GO:0008283//cell population proliferation;GO:0015031//protein transport;GO:0016477//cell migration;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0050708//regulation of protein secretion;GO:0050709//negative regulation of protein secretion;GO:0061136//regulation of proteasomal protein catabolic process	--
ENSG00000007392	18.021	17.315	20.106	15.887	20.08	18.568	557	554	458	364	529	410	LUC7L	LUC7 like [Source:HGNC Symbol;Acc:HGNC:6723]	-	-	-	-	GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome	GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0050733//RS domain binding	GO:0006376//mRNA splice site selection;GO:0045843//negative regulation of striated muscle tissue development	--
ENSG00000007402	0.582	0.618	0.607	0.651	0.862	0.515	60	73	49	55	70	41	CACNA2D2	calcium voltage-gated channel auxiliary subunit alpha2delta 2 [Source:HGNC Symbol;Acc:HGNC:1400]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04859;K04859;K04859;K04859;K04859;K04859;K04859	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000007516	0.556	0.743	0.634	0.72	0.551	0.263	50.01	52.02	44	28	28	18	BAIAP3	BAI1 associated protein 3 [Source:HGNC Symbol;Acc:HGNC:948]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15621	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0098793//presynapse	GO:0000149//SNARE binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019905//syntaxin binding;GO:0046872//metal ion binding	"GO:0001956//positive regulation of neurotransmitter secretion;GO:0006887//exocytosis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042147//retrograde transport, endosome to Golgi;GO:1905413//regulation of dense core granule exocytosis;GO:1990502//dense core granule maturation"	--
ENSG00000007520	30.659	31.874	33.749	41.864	38.766	38.563	761.99	793.98	620	771	805	702	TSR3	TSR3 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:14175]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0016740//transferase activity;GO:0106388//18S rRNA aminocarboxypropyltransferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0000154//rRNA modification;GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis	--
ENSG00000007541	24.363	27.628	26.631	26.955	27.579	27.709	1254	1449	1044	1086	1224	1109	PIGQ	phosphatidylinositol glycan anchor biosynthesis class Q [Source:HGNC Symbol;Acc:HGNC:14135]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03860;K03860	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006506//GPI anchor biosynthetic process	--
ENSG00000007545	4.962	4.109	4.933	4.616	5.056	13.547	731.07	666.67	589.33	492.87	680.64	559.3	CRAMP1	cramped chromatin regulator homolog 1 [Source:HGNC Symbol;Acc:HGNC:14122]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding	GO:0007389//pattern specification process	--
ENSG00000007866	6.862	6.714	8.067	7.684	7.167	8.204	425	418	369	348	375	358	TEAD3	TEA domain transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11716]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K09448;K09448	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007565//female pregnancy;GO:0035329//hippo signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0055059//asymmetric neuroblast division"	TEA
ENSG00000007908	0.043	0.05	0.058	0	0	0	3	4	3	0	0	0	SELE	selectin E [Source:HGNC Symbol;Acc:HGNC:10718]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic	ko05417//Lipid and atherosclerosis;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04668//TNF signaling pathway;ko05143//African trypanosomiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05144//Malaria	K06494;K06494;K06494;K06494;K06494;K06494;K06494	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030863//cortical cytoskeleton;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0043274//phospholipase binding;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding	GO:0002092//positive regulation of receptor internalization;GO:0002523//leukocyte migration involved in inflammatory response;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007202//activation of phospholipase C activity;GO:0019722//calcium-mediated signaling;GO:0030029//actin filament-based process;GO:0032496//response to lipopolysaccharide;GO:0034097//response to cytokine;GO:0034612//response to tumor necrosis factor;GO:0050727//regulation of inflammatory response;GO:0050901//leukocyte tethering or rolling;GO:0070555//response to interleukin-1;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000007923	15.756	15.633	16.46	17.419	17.296	16.947	1041.49	1044.01	807.52	844.33	970.9	815.02	DNAJC11	DnaJ heat shock protein family (Hsp40) member C11 [Source:HGNC Symbol;Acc:HGNC:25570]	-	-	-	-	GO:0001401//SAM complex;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation	--
ENSG00000007933	0	0	0	0	0	0	0	0	0	0	0	0	FMO3	flavin containing dimethylaniline monoxygenase 3 [Source:HGNC Symbol;Acc:HGNC:3771]	Metabolism;Metabolism	Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko00982//Drug metabolism - cytochrome P450;ko00430//Taurine and hypotaurine metabolism	K00485;K00485	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0034899//trimethylamine monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	-	--
ENSG00000007944	29.096	27.168	25.031	20.191	21.715	22.533	1854	1740	1178	953	1169	1044	MYLIP	myosin regulatory light chain interacting protein [Source:HGNC Symbol;Acc:HGNC:21155]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K10637	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007399//nervous system development;GO:0010977//negative regulation of neuron projection development;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0016567//protein ubiquitination;GO:0031648//protein destabilization;GO:0032803//regulation of low-density lipoprotein particle receptor catabolic process;GO:0042632//cholesterol homeostasis;GO:0045732//positive regulation of protein catabolic process	--
ENSG00000007952	0	0.055	0	0	0.082	0	0	2	0	0	1	0	NOX1	NADPH oxidase 1 [Source:HGNC Symbol;Acc:HGNC:7889]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Cardiovascular disease;Cardiovascular disease;Development and regeneration;Endocrine and metabolic disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications	K08008;K08008;K08008;K08008;K08008;K08008;K08008	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043020//NADPH oxidase complex	GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0050661//NADP binding	GO:0001525//angiogenesis;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0006739//NADP metabolic process;GO:0006811//ion transport;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042554//superoxide anion generation;GO:0042743//hydrogen peroxide metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0045726//positive regulation of integrin biosynthetic process;GO:0045730//respiratory burst;GO:0046330//positive regulation of JNK cascade;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051454//intracellular pH elevation;GO:0071455//cellular response to hyperoxia;GO:0072592//oxygen metabolic process;GO:0072593//reactive oxygen species metabolic process;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1990451//cellular stress response to acidic pH	--
ENSG00000007968	0.084	0.046	0.101	0.088	0.132	0.077	9	5	8	7	12	6	E2F2	E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05226//Gastric cancer;ko04110//Cell cycle;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05219//Bladder cancer	K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389;K09389	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0035189//Rb-E2F complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007049//cell cycle;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1903671//negative regulation of sprouting angiogenesis;GO:1990086//lens fiber cell apoptotic process"	E2F
ENSG00000008018	94.475	93.238	103.227	94.452	90.176	95.784	1746	1732	1409	1293	1408	1288	PSMB1	proteasome 20S subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9537]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02732;K02732;K02732;K02732;K02732;K02732;K02732;K02732	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000008056	0.635	1.68	0.693	0.266	1.25	0.983	42	54	22	13	25	29	SYN1	synapsin I [Source:HGNC Symbol;Acc:HGNC:11494]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0043229//intracellular organelle;GO:0044297//cell body;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098850//extrinsic component of synaptic vesicle membrane;GO:0098993//anchored component of synaptic vesicle membrane	GO:0003779//actin binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding	GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0046928//regulation of neurotransmitter secretion;GO:0048666//neuron development;GO:0050808//synapse organization;GO:0097091//synaptic vesicle clustering;GO:0098693//regulation of synaptic vesicle cycle;GO:0099504//synaptic vesicle cycle;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000008083	1.823	1.858	1.827	1.843	2.541	2.208	223	226	167	170	262	200	JARID2	jumonji and AT-rich interaction domain containing 2 [Source:HGNC Symbol;Acc:HGNC:6196]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11478	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0035097//histone methyltransferase complex;GO:0035098//ESC/E(Z) complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0032452//histone demethylase activity;GO:0043130//ubiquitin binding;GO:0061649//ubiquitin modification-dependent histone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001889//liver development;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0016577//histone demethylation;GO:0030154//cell differentiation;GO:0031061//negative regulation of histone methylation;GO:0042127//regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048863//stem cell differentiation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:1902682//protein localization to pericentric heterochromatin;GO:1990830//cellular response to leukemia inhibitory factor"	ARID
ENSG00000008086	1.494	1.487	1.172	0.788	0.833	0.941	280	263	143	119	166	142	CDKL5	cyclin dependent kinase like 5 [Source:HGNC Symbol;Acc:HGNC:11411]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0032587//ruffle membrane;GO:0032839//dendrite cytoplasm;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0044294//dendritic growth cone;GO:0097542//ciliary tip;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0106310//protein serine kinase activity	GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0043547//positive regulation of GTPase activity;GO:0045773//positive regulation of axon extension;GO:0046777//protein autophosphorylation;GO:0050773//regulation of dendrite development;GO:0050775//positive regulation of dendrite morphogenesis;GO:0051726//regulation of cell cycle;GO:0099175//regulation of postsynapse organization;GO:1902017//regulation of cilium assembly	--
ENSG00000008118	0.259	0.101	0.193	0.212	0.139	0.135	5	4	3	8	6	5	CAMK1G	calcium/calmodulin dependent protein kinase IG [Source:HGNC Symbol;Acc:HGNC:14585]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Endocrine system;Endocrine system;Cancer: specific types	ko04020//Calcium signaling pathway;ko04921//Oxytocin signaling pathway;ko04925//Aldosterone synthesis and secretion;ko05214//Glioma	K08794;K08794;K08794;K08794	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043005//neuron projection	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation	--
ENSG00000008128	8.73	6.066	7.59	6.723	6.573	8.582	343.96	310.96	289.93	242.25	278.79	312.11	CDK11A	cyclin dependent kinase 11A [Source:HGNC Symbol;Acc:HGNC:1730]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000278//mitotic cell cycle;GO:0001558//regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016310//phosphorylation;GO:0043484//regulation of RNA splicing;GO:0050684//regulation of mRNA processing"	--
ENSG00000008130	32.141	33.969	36.824	34.585	32.242	36.87	2072	2186	1748	1680	1800	1683	NADK	NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00858;K00858	GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0046872//metal ion binding"	GO:0006741//NADP biosynthetic process;GO:0016310//phosphorylation;GO:0019674//NAD metabolic process;GO:0046034//ATP metabolic process	--
ENSG00000008196	0	0	0	0	0	0	0	0	0	0	0	0	TFAP2B	transcription factor AP-2 beta [Source:HGNC Symbol;Acc:HGNC:11743]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0003091//renal water homeostasis;GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007423//sensory organ development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010467//gene expression;GO:0010842//retina layer formation;GO:0010960//magnesium ion homeostasis;GO:0030510//regulation of BMP signaling pathway;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0035810//positive regulation of urine volume;GO:0035909//aorta morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043588//skin development;GO:0045444//fat cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048485//sympathetic nervous system development;GO:0048745//smooth muscle tissue development;GO:0048856//anatomical structure development;GO:0050796//regulation of insulin secretion;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0072017//distal tubule development;GO:0072044//collecting duct development;GO:0072210//metanephric nephron development;GO:0097070//ductus arteriosus closure;GO:0097275//cellular ammonium homeostasis;GO:0097276//cellular creatinine homeostasis;GO:0097277//cellular urea homeostasis"	AP-2
ENSG00000008197	0	0	0	0	0	0	0	0	0	0	0	0	TFAP2D	transcription factor AP-2 delta [Source:HGNC Symbol;Acc:HGNC:15581]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0042127//regulation of cell population proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development;GO:0061379//inferior colliculus development"	AP-2
ENSG00000008226	0.265	0.203	0.135	0.156	0.052	0.097	33.11	27.16	14.31	16.14	5	8	DLEC1	DLEC1 cilia and flagella associated protein [Source:HGNC Symbol;Acc:HGNC:2899]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding	GO:0002357//defense response to tumor cell;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation	--
ENSG00000008256	11.389	10.175	10.844	9.938	11.049	11.157	1059	951	745	685	868	755	CYTH3	cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway	K18441;K18441;K18441;K18441;K18441	GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	"GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding"	GO:0032012//regulation of ARF protein signal transduction;GO:0045785//positive regulation of cell adhesion;GO:0048193//Golgi vesicle transport;GO:0050790//regulation of catalytic activity;GO:0090162//establishment of epithelial cell polarity	--
ENSG00000008277	1.366	0.822	0.538	0.813	0.695	0.855	139	128	76	86	87	107	ADAM22	ADAM metallopeptidase domain 22 [Source:HGNC Symbol;Acc:HGNC:201]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007417//central nervous system development;GO:0008344//adult locomotory behavior;GO:0014037//Schwann cell differentiation;GO:0022011//myelination in peripheral nervous system;GO:0042063//gliogenesis;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane	--
ENSG00000008282	35.782	31.463	30.904	28.988	31.913	34.983	1561	1391	1006	944	1189	1116	SYPL1	synaptophysin like 1 [Source:HGNC Symbol;Acc:HGNC:11507]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0030285//integral component of synaptic vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007268//chemical synaptic transmission	--
ENSG00000008283	18.619	17.782	20.461	17.396	16.584	17.273	922	907	699	638	736	651	CYB561	cytochrome b561 [Source:HGNC Symbol;Acc:HGNC:2571]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042584//chromaffin granule membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0140575//transmembrane monodehydroascorbate reductase activity	GO:0006879//cellular iron ion homeostasis;GO:0022900//electron transport chain;GO:0140576//ascorbate homeostasis	--
ENSG00000008294	28.118	26.291	24.305	21.127	21.266	21.489	3147	3071	2087	1886	2117	1960	SPAG9	sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0034451//centriolar satellite;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0019894//kinesin binding;GO:0030159//signaling receptor complex adaptor activity;GO:0042802//identical protein binding	"GO:0001933//negative regulation of protein phosphorylation;GO:0016192//vesicle-mediated transport;GO:0030335//positive regulation of cell migration;GO:0032418//lysosome localization;GO:0042147//retrograde transport, endosome to Golgi;GO:0043410//positive regulation of MAPK cascade;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0051146//striated muscle cell differentiation;GO:1903860//negative regulation of dendrite extension"	--
ENSG00000008300	0.323	0.253	0.361	0.224	0.406	0.378	80	63	66	41	85	68	CELSR3	cadherin EGF LAG seven-pass G-type receptor 3 [Source:HGNC Symbol;Acc:HGNC:3230]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0098609//cell-cell adhesion"	--
ENSG00000008311	6.225	4.467	4.494	5.323	5.626	6.699	733	515	376	411	544	515	AASS	aminoadipate-semialdehyde synthase [Source:HGNC Symbol;Acc:HGNC:17366]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K14157;K14157	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004753//saccharopine dehydrogenase activity;GO:0004754//saccharopine dehydrogenase (NAD+, L-lysine-forming) activity;GO:0016491//oxidoreductase activity;GO:0042393//histone binding;GO:0047130//saccharopine dehydrogenase (NADP+, L-lysine-forming) activity;GO:0047131//saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006554//lysine catabolic process;GO:0008152//metabolic process;GO:0019477//L-lysine catabolic process;GO:0019878//lysine biosynthetic process via aminoadipic acid;GO:0031061//negative regulation of histone methylation;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine	--
ENSG00000008323	2.287	2.467	2.447	2.437	2.691	2.948	131	151	103	90	140	129	PLEKHG6	pleckstrin homology and RhoGEF domain containing G6 [Source:HGNC Symbol;Acc:HGNC:25562]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0030054//cell junction;GO:0032154//cleavage furrow;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000008324	8.072	5.956	7.295	7.833	7.521	6.708	176	130	117	126	138	106	SS18L2	SS18 like 2 [Source:HGNC Symbol;Acc:HGNC:15593]	-	-	-	-	GO:0005634//nucleus	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050775//positive regulation of dendrite morphogenesis"	--
ENSG00000008382	12.179	12.446	11.177	16.966	13.995	10.736	355	372	272	355	365	256	MPND	MPN domain containing [Source:HGNC Symbol;Acc:HGNC:25934]	-	-	-	-	-	GO:0003713//transcription coactivator activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0006338//chromatin remodeling;GO:0006508//proteolysis;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000008394	67.489	65.907	77.214	78.792	78.492	108.259	1282	1242	1001	1102	1220	1482	MGST1	microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0034635//glutathione transport;GO:0071449//cellular response to lipid hydroperoxide;GO:0098869//cellular oxidant detoxification	--
ENSG00000008405	12.355	11.594	9.829	8.467	9.211	12.942	558	574	427	374	401	465	CRY1	cryptochrome circadian regulator 1 [Source:HGNC Symbol;Acc:HGNC:2384]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K02295	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0009881//photoreceptor activity;GO:0009882//blue light photoreceptor activity;GO:0016829//lyase activity;GO:0016922//nuclear receptor binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0042826//histone deacetylase binding;GO:0070888//E-box binding;GO:0071949//FAD binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006094//gluconeogenesis;GO:0006975//DNA damage induced protein phosphorylation;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009785//blue light signaling pathway;GO:0014823//response to activity;GO:0018298//protein-chromophore linkage;GO:0019915//lipid storage;GO:0031397//negative regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0033762//response to glucagon;GO:0042593//glucose homeostasis;GO:0042752//regulation of circadian rhythm;GO:0042754//negative regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045721//negative regulation of gluconeogenesis;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050896//response to stimulus;GO:2000001//regulation of DNA damage checkpoint;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:2000850//negative regulation of glucocorticoid secretion"	--
ENSG00000008438	0	0	0	0	0	0	0	0	0	0	0	0	PGLYRP1	peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904]	-	-	-	-	GO:0005576//extracellular region;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:0097013//phagocytic vesicle lumen;GO:1904724//tertiary granule lumen	GO:0008270//zinc ion binding;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0016019//peptidoglycan immune receptor activity;GO:0042834//peptidoglycan binding	GO:0002376//immune system process;GO:0009253//peptidoglycan catabolic process;GO:0009617//response to bacterium;GO:0016045//detection of bacterium;GO:0031640//killing of cells of other organism;GO:0032689//negative regulation of interferon-gamma production;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0051701//biological process involved in interaction with host;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000008441	208.898	215.441	191.078	146.892	162.155	143.996	15326	15603	10276	7991	9735	7654	NFIX	nuclear factor I X [Source:HGNC Symbol;Acc:HGNC:7788]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	CTF/NFI
ENSG00000008513	6.266	5.841	7.584	7.278	8.418	10.901	868	784	781	762	997	1026	ST3GAL1	"ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K00780;K00780;K00780;K00780;K00780	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0032588//trans-Golgi network membrane;GO:0070062//extracellular exosome;GO:1990675//Golgi medial cisterna membrane;GO:1990676//Golgi trans cisterna membrane	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047288//monosialoganglioside sialyltransferase activity"	"GO:0002319//memory B cell differentiation;GO:0006054//N-acetylneuraminate metabolic process;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006629//lipid metabolic process;GO:0010706//ganglioside biosynthetic process via lactosylceramide;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0019082//viral protein processing;GO:0097503//sialylation;GO:1905403//negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:1990743//protein sialylation"	--
ENSG00000008516	0.144	0.065	0.124	0.213	0.249	0.126	11	5	7	12	16	7	MMP25	matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K08003	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0035579//specific granule membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0060022//hard palate development	--
ENSG00000008517	2.882	4.697	3.222	1.569	0.921	0.957	55	86	47	22	15	12	IL32	interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22632	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016020//membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006952//defense response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0034346//positive regulation of type III interferon production;GO:1903901//negative regulation of viral life cycle;GO:1905636//positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	--
ENSG00000008710	14.266	13.294	17.14	14.221	19.656	17.941	1977	2114	1830	1562.17	2187.94	1905	PKD1	"polycystin 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:9008]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0002133//polycystin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0031514//motile cilium;GO:0034703//cation channel complex;GO:0034704//calcium channel complex;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030246//carbohydrate binding;GO:0042813//Wnt-activated receptor activity;GO:0044325//transmembrane transporter binding	GO:0001502//cartilage condensation;GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0006611//protein export from nucleus;GO:0006807//nitrogen compound metabolic process;GO:0006816//calcium ion transport;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007160//cell-matrix adhesion;GO:0007161//calcium-independent cell-matrix adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0016055//Wnt signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0021510//spinal cord development;GO:0021915//neural tube development;GO:0030010//establishment of cell polarity;GO:0030155//regulation of cell adhesion;GO:0032092//positive regulation of protein binding;GO:0034405//response to fluid shear stress;GO:0036303//lymph vessel morphogenesis;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043588//skin development;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048806//genitalia development;GO:0050982//detection of mechanical stimulus;GO:0051216//cartilage development;GO:0051290//protein heterotetramerization;GO:0051726//regulation of cell cycle;GO:0060236//regulation of mitotic spindle organization;GO:0060428//lung epithelium development;GO:0060674//placenta blood vessel development;GO:0061136//regulation of proteasomal protein catabolic process;GO:0070588//calcium ion transmembrane transport;GO:0072164//mesonephric tubule development;GO:0072177//mesonephric duct development;GO:0072205//metanephric collecting duct development;GO:0072218//metanephric ascending thin limb development;GO:0072237//metanephric proximal tubule development;GO:0072287//metanephric distal tubule morphogenesis;GO:0098609//cell-cell adhesion;GO:0198738//cell-cell signaling by wnt;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000008735	0.491	0.412	0.573	0.834	0.661	0.697	58	49	50	73	66	60	MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:6883]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04435	GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body	GO:0001540//amyloid-beta binding;GO:0005078//MAP-kinase scaffold activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0044877//protein-containing complex binding	"GO:0001662//behavioral fear response;GO:0007172//signal complex assembly;GO:0007254//JNK cascade;GO:0007617//mating behavior;GO:0010469//regulation of signaling receptor activity;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0035176//social behavior;GO:0046328//regulation of JNK cascade;GO:0046958//nonassociative learning;GO:0048813//dendrite morphogenesis;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:2000310//regulation of NMDA receptor activity;GO:2000311//regulation of AMPA receptor activity;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000008838	29.828	29.797	33.001	37.623	36.98	31.795	1482	1616	1245	1328	1501	1197	MED24	mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15167	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0044877//protein-containing complex binding;GO:0046966//thyroid hormone receptor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0016567//protein ubiquitination;GO:0016573//histone acetylation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000008853	22.147	22.551	24.466	23.377	23.453	23.049	2276.5	2320.6	1836.4	1744.32	2015.16	1714	RHOBTB2	Rho related BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18756]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K07868	GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043652//engulfment of apoptotic cell	--
ENSG00000008869	5.518	5.469	5.872	4.419	5.166	5.483	794	791	624	471	628	574	HEATR5B	HEAT repeat containing 5B [Source:HGNC Symbol;Acc:HGNC:29273]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030136//clathrin-coated vesicle;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	"GO:0006897//endocytosis;GO:0008104//protein localization;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000008952	35.348	33.287	30.13	18.95	26.131	27.645	2616	2282	1541	1071	1478	1475	SEC62	"SEC62 homolog, preprotein translocation factor [Source:HGNC Symbol;Acc:HGNC:11846]"	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko03060//Protein export	K12275;K12275	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0038023//signaling receptor activity	"GO:0006613//cotranslational protein targeting to membrane;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0015031//protein transport;GO:0031204//posttranslational protein targeting to membrane, translocation"	--
ENSG00000008988	529.042	539.51	504.01	534.351	454.741	449.399	5949	6024	4170	4401	4278	3691	RPS20	ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02969;K02969	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0097371//MDM2/MDM4 family protein binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000009307	203.894	182.764	173.784	155.878	154.448	168.626	15454	13954	9787	8758	10014	9337	CSDE1	cold shock domain containing E1 [Source:HGNC Symbol;Acc:HGNC:29905]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010494//cytoplasmic stress granule;GO:0070937//CRD-mediated mRNA stability complex;GO:0106002//mCRD-mediated mRNA stability complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035613//RNA stem-loop binding	"GO:0006446//regulation of translational initiation;GO:0008584//male gonad development;GO:0034063//stress granule assembly;GO:0070934//CRD-mediated mRNA stabilization;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0075522//IRES-dependent viral translational initiation;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2000767//positive regulation of cytoplasmic translation"	CSD
ENSG00000009335	22.719	21.884	20.951	18.263	21.024	22.989	2457	2373	1666	1463	1921	1809	UBE3C	ubiquitin protein ligase E3C [Source:HGNC Symbol;Acc:HGNC:16803]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10589	GO:0000502//proteasome complex;GO:0005634//nucleus	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0035519//protein K29-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000009413	6.438	3.218	4.145	2.799	3.619	3.623	1351	722	547	403	683	588	REV3L	"REV3 like, DNA directed polymerase zeta catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9968]"	Human Diseases;Genetic Information Processing	Drug resistance: antineoplastic;Replication and repair	ko01524//Platinum drug resistance;ko03460//Fanconi anemia pathway	K02350;K02350	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016035//zeta DNA polymerase complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0019985//translesion synthesis;GO:0042276//error-prone translesion synthesis	--
ENSG00000009694	0.352	0.212	0.35	0.288	0.425	0.381	94	57	69	57	96	74	TENM1	teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm	GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0006359//regulation of transcription by RNA polymerase III;GO:0006955//immune response;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0030838//positive regulation of actin filament polymerization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0048666//neuron development;GO:0051491//positive regulation of filopodium assembly;GO:0090316//positive regulation of intracellular protein transport	--
ENSG00000009709	0	0	0	0	0.009	0	0	0	0	0	1	0	PAX7	paired box 7 [Source:HGNC Symbol;Acc:HGNC:8621]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09381	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0009653//anatomical structure morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0048856//anatomical structure development"	PAX
ENSG00000009724	0.471	0.215	0.399	0.557	0.325	0.486	24	11	15	21	14	18	MASP2	MBL associated serine protease 2 [Source:HGNC Symbol;Acc:HGNC:6902]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K03993;K03993;K03993	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0001855//complement component C4b binding;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response"	--
ENSG00000009765	0.019	0.013	0	0	0	0	3	2	0	0	0	0	IYD	iodotyrosine deiodinase [Source:HGNC Symbol;Acc:HGNC:21071]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K17231	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0140616//iodotyrosine deiodinase activity	GO:0006570//tyrosine metabolic process;GO:0042403//thyroid hormone metabolic process	--
ENSG00000009780	2.097	2.471	3.332	1.939	2.109	2.114	107	99	89	62	85	70	FAM76A	family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000009790	0	0	0	0	0.588	0	0	0	0	0	6	0	TRAF3IP3	TRAF3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:30766]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000009830	14.819	20.451	17.372	17.982	18.212	17.503	1222	1381	999	934	1182	995	POMT2	protein O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:19743]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00515//Mannose type O-glycan biosynthesis	K00728;K00728;K00728	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0035269//protein O-linked mannosylation;GO:0097502//mannosylation;GO:1904100//positive regulation of protein O-linked glycosylation	--
ENSG00000009844	25.479	26.678	24.808	23.365	22.262	24.718	1008	1026	702	657.01	721	685.05	VTA1	vesicle trafficking 1 [Source:HGNC Symbol;Acc:HGNC:20954]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12199	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0046755//viral budding;GO:0071985//multivesicular body sorting pathway;GO:1904903//ESCRT III complex disassembly	--
ENSG00000009950	0.108	0.047	0.542	0.144	0.41	0.659	7	3	7	4	12	14	MLXIPL	MLX interacting protein like [Source:HGNC Symbol;Acc:HGNC:12744]	Human Diseases;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease	ko04932//Non-alcoholic fatty liver disease;ko04931//Insulin resistance	K09113;K09113	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0035538//carbohydrate response element binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0010255//glucose mediated signaling pathway;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0042593//glucose homeostasis;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045821//positive regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046889//positive regulation of lipid biosynthetic process;GO:0055089//fatty acid homeostasis;GO:0070328//triglyceride homeostasis;GO:0090324//negative regulation of oxidative phosphorylation;GO:0097009//energy homeostasis"	bHLH
ENSG00000009954	17.098	14.819	14.573	9.815	11.734	11.574	2054	1794	1293	878	1206	1007	BAZ1B	bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961]	-	-	-	-	GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005730//nucleolus;GO:0043596//nuclear replication fork;GO:0090535//WICH complex;GO:0110016//B-WICH complex	GO:0000166//nucleotide binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035173//histone kinase activity;GO:0042393//histone binding;GO:0046872//metal ion binding	GO:0006333//chromatin assembly or disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0016584//nucleosome positioning;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035066//positive regulation of histone acetylation;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:1905213//negative regulation of mitotic chromosome condensation;GO:1990164//histone H2A phosphorylation;GO:2001020//regulation of response to DNA damage stimulus	--
ENSG00000010017	16.127	13.012	13.31	11.29	11.534	14.764	1132	918	690	587	684	754	RANBP9	RAN binding protein 9 [Source:HGNC Symbol;Acc:HGNC:13727]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031267//small GTPase binding	GO:0007010//cytoskeleton organization;GO:0007020//microtubule nucleation;GO:0007166//cell surface receptor signaling pathway;GO:0065003//protein-containing complex assembly;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1902993//positive regulation of amyloid precursor protein catabolic process	--
ENSG00000010030	0.202	0.129	0.091	0.045	0.089	0.155	6	4	2	1	2	3	ETV7	ETS variant transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:18160]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K03211	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation"	ETS
ENSG00000010072	4.812	2.959	2.897	2.746	3.217	3.537	317.92	197.84	145.14	128.53	172.92	170.53	SPRTN	SprT-like N-terminal domain [Source:HGNC Symbol;Acc:HGNC:25356]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0016540//protein autoprocessing;GO:0019985//translesion synthesis;GO:0031398//positive regulation of protein ubiquitination;GO:0050896//response to stimulus;GO:0106300//protein-DNA covalent cross-linking repair	--
ENSG00000010165	8.52	8.512	9.556	9.117	8.467	8.634	593	593	492	467	496	437	METTL13	"methyltransferase 13, eEF1A lysine and N-terminal methyltransferase [Source:HGNC Symbol;Acc:HGNC:24248]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008152//metabolic process;GO:0032259//methylation;GO:1902807//negative regulation of cell cycle G1/S phase transition	--
ENSG00000010219	5.904	7.04	7.155	6.943	5.098	6.321	257	297	225	173	191	199	DYRK4	dual specificity tyrosine phosphorylation regulated kinase 4 [Source:HGNC Symbol;Acc:HGNC:3095]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation	--
ENSG00000010244	58.328	56.424	58.301	52.517	51.639	57.395	2884	2739	2168	1937	2175	2144	ZNF207	zinc finger protein 207 [Source:HGNC Symbol;Acc:HGNC:12998]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:1990047//spindle matrix"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008201//heparin binding;GO:0046872//metal ion binding	GO:0000070//mitotic sister chromatid segregation;GO:0001578//microtubule bundle formation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0046785//microtubule polymerization;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0051983//regulation of chromosome segregation;GO:0090307//mitotic spindle assembly	Others
ENSG00000010256	72.846	67.181	80.788	93.242	82.907	94.483	2410	2234	1974	2279	2311	2268	UQCRC1	ubiquinol-cytochrome c reductase core protein 1 [Source:HGNC Symbol;Acc:HGNC:12585]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414;K00414	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008121//ubiquinol-cytochrome-c reductase activity;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	"GO:0006119//oxidative phosphorylation;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0009060//aerobic respiration;GO:0014823//response to activity;GO:0043279//response to alkaloid;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000010270	26.374	22.941	26.738	27.963	25.482	26.77	886	765	658	664	714	642	STARD3NL	STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044232//organelle membrane contact site;GO:0140284//endoplasmic reticulum-endosome membrane contact site	GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0042803//protein homodimerization activity	GO:0099044//vesicle tethering to endoplasmic reticulum	--
ENSG00000010278	34.004	34.444	35.877	25.12	31.486	34.922	889	905	693	497	713	642	CD9	CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06460	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031092//platelet alpha granule membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0008285//negative regulation of cell population proliferation;GO:0008347//glial cell migration;GO:0014905//myoblast fusion involved in skeletal muscle regeneration;GO:0030168//platelet activation;GO:0030913//paranodal junction assembly;GO:0031623//receptor internalization;GO:0035036//sperm-egg recognition;GO:0051271//negative regulation of cellular component movement;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0090331//negative regulation of platelet aggregation;GO:1905521//regulation of macrophage migration	--
ENSG00000010282	20.245	24.002	16.281	16.48	18.95	13.749	749	871	437	450	591	377	HHATL	hedgehog acyltransferase like [Source:HGNC Symbol;Acc:HGNC:13242]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K24679	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0016746//acyltransferase activity	GO:0060262//negative regulation of N-terminal protein palmitoylation	--
ENSG00000010292	11.301	10.109	9.714	9.105	9.521	10.062	908	911	718	675	805	616	NCAPD2	non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305]	-	-	-	-	"GO:0000228//nuclear chromosome;GO:0000779//condensed chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane"	GO:0005515//protein binding;GO:0042393//histone binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000010295	5.073	5.197	5.29	6.181	5.386	5.534	284	291	219	255	255	225	IFFO1	intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0006303//double-strand break repair via nonhomologous end joining;GO:1990166//protein localization to site of double-strand break;GO:1990683//DNA double-strand break attachment to nuclear envelope	--
ENSG00000010310	0.554	0.833	0.856	0.852	0.755	1.02	34	37	35	37	30	40	GIPR	gastric inhibitory polypeptide receptor [Source:HGNC Symbol;Acc:HGNC:4271]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway	K04580;K04580	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016519//gastric inhibitory peptide receptor activity;GO:0017046//peptide hormone binding;GO:0120022//glucagon family peptide binding	GO:0002029//desensitization of G protein-coupled receptor signaling pathway;GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007584//response to nutrient;GO:0009749//response to glucose;GO:0031018//endocrine pancreas development;GO:0032024//positive regulation of insulin secretion;GO:0038192//gastric inhibitory peptide signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0048678//response to axon injury;GO:0050796//regulation of insulin secretion;GO:0051592//response to calcium ion;GO:0070542//response to fatty acid	--
ENSG00000010318	0.667	0.865	0.671	0.924	0.768	0.595	27	35	20	29	27	16	PHF7	PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000010319	0.193	0.163	0.23	0.207	0.126	0.133	20	17	14	9	11	10	SEMA3G	semaphorin 3G [Source:HGNC Symbol;Acc:HGNC:30400]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000010322	51.113	52.353	52.171	52.3	56.002	51.129	5021	5161	3774	3858	4636	3613	NISCH	nischarin [Source:HGNC Symbol;Acc:HGNC:18006]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0055037//recycling endosome	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0016601//Rac protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration	--
ENSG00000010327	0.043	0	0.008	0.016	0.036	0.017	7	0	1	2	5	2	STAB1	stabilin 1 [Source:HGNC Symbol;Acc:HGNC:18628]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005044//scavenger receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0015035//protein-disulfide reductase activity;GO:0030169//low-density lipoprotein particle binding	GO:0006898//receptor-mediated endocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0016525//negative regulation of angiogenesis;GO:0042742//defense response to bacterium	--
ENSG00000010361	19.196	17.308	24.904	19.57	19.048	20.148	590.28	544.29	507	443.55	495.5	417	FUZ	fuzzy planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:26219]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0001736//establishment of planar polarity;GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0008285//negative regulation of cell population proliferation;GO:0008589//regulation of smoothened signaling pathway;GO:0010172//embryonic body morphogenesis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0021915//neural tube development;GO:0030030//cell projection organization;GO:0030336//negative regulation of cell migration;GO:0042073//intraciliary transport;GO:0045724//positive regulation of cilium assembly;GO:0048704//embryonic skeletal system morphogenesis;GO:0060271//cilium assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090301//negative regulation of neural crest formation;GO:1902017//regulation of cilium assembly;GO:1905515//non-motile cilium assembly;GO:2000314//negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	--
ENSG00000010379	76.238	86.813	81.98	64.003	64.876	56.851	3119	3499	2403	1891	2292	1627	SLC6A13	solute carrier family 6 member 13 [Source:HGNC Symbol;Acc:HGNC:11046]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle	K05046;K05046	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043005//neuron projection;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0005308//creatine transmembrane transporter activity;GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005368//taurine transmembrane transporter activity;GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015185//gamma-aminobutyric acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0006836//neurotransmitter transport;GO:0010940//positive regulation of necrotic cell death;GO:0015718//monocarboxylic acid transport;GO:0015734//taurine transport;GO:0015881//creatine transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051936//gamma-aminobutyric acid reuptake;GO:0051939//gamma-aminobutyric acid import;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0089718//amino acid import across plasma membrane;GO:0150104//transport across blood-brain barrier	--
ENSG00000010404	22.568	22.778	21.208	15.909	16.611	16.189	2258.96	2061.19	1294.84	1110.55	1335.21	1106.79	IDS	iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01136;K01136;K01136	GO:0005764//lysosome;GO:0043202//lysosomal lumen	GO:0003824//catalytic activity;GO:0004423//iduronate-2-sulfatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006027//glycosaminoglycan catabolic process	--
ENSG00000010438	0.061	0	0	0	0.073	0	1	0	0	0	1	0	PRSS3	serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Digestive system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01312;K01312;K01312;K01312	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:1904724//tertiary granule lumen	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007586//digestion;GO:0019730//antimicrobial humoral response;GO:0031638//zymogen activation;GO:0043542//endothelial cell migration	--
ENSG00000010539	2.79	3.722	3.289	3.943	2.425	3.211	161	186	136	150	112	131	ZNF200	zinc finger protein 200 [Source:HGNC Symbol;Acc:HGNC:12993]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008150//biological_process	zf-C2H2
ENSG00000010610	0.095	0.126	0.171	0.382	0.225	0.174	6	8	8	16	12	8	CD4	CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Immune disease;Immune system;Immune system;Immune system;Cancer: overview;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04612//Antigen processing and presentation	K06454;K06454;K06454;K06454;K06454;K06454;K06454;K06454;K06454;K06454;K06454;K06454	GO:0005769//early endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042101//T cell receptor complex;GO:0045121//membrane raft	GO:0001618//virus receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015026//coreceptor activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0023026//MHC class II protein complex binding;GO:0038023//signaling receptor activity;GO:0042011//interleukin-16 binding;GO:0042012//interleukin-16 receptor activity;GO:0042289//MHC class II protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:1990782//protein tyrosine kinase binding	"GO:0001934//positive regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030217//T cell differentiation;GO:0030225//macrophage differentiation;GO:0032507//maintenance of protein location in cell;GO:0032743//positive regulation of interleukin-2 production;GO:0033674//positive regulation of kinase activity;GO:0035397//helper T cell enhancement of adaptive immune response;GO:0035723//interleukin-15-mediated signaling pathway;GO:0042110//T cell activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0045058//T cell selection;GO:0045657//positive regulation of monocyte differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046598//positive regulation of viral entry into host cell;GO:0046718//viral entry into host cell;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050829//defense response to Gram-negative bacterium;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050863//regulation of T cell activation;GO:0050870//positive regulation of T cell activation;GO:0051924//regulation of calcium ion transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus"	--
ENSG00000010626	7.354	8.997	7.827	6.903	5.706	7.571	186	217	152	123	132	134	LRRC23	leucine rich repeat containing 23 [Source:HGNC Symbol;Acc:HGNC:19138]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000010671	0.185	0	0.059	0.251	0.078	0.124	5	0	2	5	3	5	BTK	Bruton tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1133]	Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Signal transduction;Immune system;Immune system;Development and regeneration;Immune system;Immune disease	ko05169//Epstein-Barr virus infection;ko04064//NF-kappa B signaling pathway;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko05340//Primary immunodeficiency	K07370;K07370;K07370;K07370;K07370;K07370;K07370	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0046872//metal ion binding"	GO:0001818//negative regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002344//B cell affinity maturation;GO:0002376//immune system process;GO:0002721//regulation of B cell cytokine production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0002902//regulation of B cell apoptotic process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007498//mesoderm development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019722//calcium-mediated signaling;GO:0030889//negative regulation of B cell proliferation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042113//B cell activation;GO:0045087//innate immune response;GO:0045579//positive regulation of B cell differentiation;GO:0048469//cell maturation;GO:0050790//regulation of catalytic activity;GO:0050853//B cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0097190//apoptotic signaling pathway;GO:0098761//cellular response to interleukin-7	--
ENSG00000010704	10.531	8.404	9.423	10.752	9.52	8.974	434	404.12	317	310	302	287	HFE	homeostatic iron regulator [Source:HGNC Symbol;Acc:HGNC:4886]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0045178//basal part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:1990712//HFE-transferrin receptor complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0039706//co-receptor binding;GO:1990459//transferrin receptor binding	"GO:0002626//negative regulation of T cell antigen processing and presentation;GO:0002725//negative regulation of T cell cytokine production;GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0010039//response to iron ion;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034756//regulation of iron ion transport;GO:0042446//hormone biosynthetic process;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0055072//iron ion homeostasis;GO:0060586//multicellular organismal iron ion homeostasis;GO:0065003//protein-containing complex assembly;GO:0071281//cellular response to iron ion;GO:0090277//positive regulation of peptide hormone secretion;GO:0098711//iron ion import across plasma membrane;GO:1900121//negative regulation of receptor binding;GO:1900122//positive regulation of receptor binding;GO:1904283//negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:1904434//positive regulation of ferrous iron binding;GO:1904437//positive regulation of transferrin receptor binding;GO:1990641//response to iron ion starvation;GO:2000008//regulation of protein localization to cell surface;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000272//negative regulation of signaling receptor activity;GO:2000273//positive regulation of signaling receptor activity;GO:2001186//negative regulation of CD8-positive, alpha-beta T cell activation"	--
ENSG00000010803	15.377	14.264	16.123	15.633	17.202	17.669	1041	966	806	776	942	801	SCMH1	Scm polycomb group protein homolog 1 [Source:HGNC Symbol;Acc:HGNC:19003]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0010369//chromocenter	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0009952//anterior/posterior pattern specification;GO:0031507//heterochromatin assembly;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000010810	28.789	34.435	29.372	32.027	32.701	35.015	1177	1334	881	967	1026	1029	FYN	"FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037]"	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes	Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cellular community - eukaryotes;Immune system;Development and regeneration;Immune system;Cardiovascular disease;Development and regeneration;Immune system;Signal transduction;Nervous system;Immune system;Cellular community - eukaryotes	ko05020//Prion disease;ko05130//Pathogenic Escherichia coli infection;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04725//Cholinergic synapse;ko04660//T cell receptor signaling pathway;ko04520//Adherens junction	K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703;K05703	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044297//cell body;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0097038//perinuclear endoplasmic reticulum;GO:0097386//glial cell projection;GO:0098685//Schaffer collateral - CA1 synapse	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0043274//phospholipase binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0046875//ephrin receptor binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0070851//growth factor receptor binding;GO:0097110//scaffold protein binding;GO:0097718//disordered domain specific binding	GO:0000304//response to singlet oxygen;GO:0001764//neuron migration;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0003015//heart process;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007612//learning;GO:0007631//feeding behavior;GO:0008360//regulation of cell shape;GO:0010629//negative regulation of gene expression;GO:0010730//negative regulation of hydrogen peroxide biosynthetic process;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0031295//T cell costimulation;GO:0031397//negative regulation of protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042177//negative regulation of protein catabolic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045471//response to ethanol;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048813//dendrite morphogenesis;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050798//activated T cell proliferation;GO:0050804//modulation of chemical synaptic transmission;GO:0050852//T cell receptor signaling pathway;GO:0050900//leukocyte migration;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0070301//cellular response to hydrogen peroxide;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090314//positive regulation of protein targeting to membrane;GO:0097062//dendritic spine maintenance;GO:1900182//positive regulation of protein localization to nucleus;GO:1900449//regulation of glutamate receptor signaling pathway;GO:1901216//positive regulation of neuron death;GO:1902951//negative regulation of dendritic spine maintenance;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:1904645//response to amyloid-beta;GO:1904646//cellular response to amyloid-beta;GO:1905232//cellular response to L-glutamate;GO:1905430//cellular response to glycine;GO:1905477//positive regulation of protein localization to membrane;GO:1905664//regulation of calcium ion import across plasma membrane;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000010818	1.894	1.519	1.568	1.646	1.314	1.354	382	309	233	251	229	202	HIVEP2	HIVEP zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4921]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000010932	1.636	1.888	1.813	3.495	3.797	2.638	73	85	60	116	143	86	FMO1	flavin containing dimethylaniline monoxygenase 1 [Source:HGNC Symbol;Acc:HGNC:3769]	Metabolism;Metabolism	Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko00982//Drug metabolism - cytochrome P450;ko00430//Taurine and hypotaurine metabolism	K00485;K00485	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	GO:0006082//organic acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006970//response to osmotic stress;GO:0009404//toxin metabolic process;GO:0032496//response to lipopolysaccharide;GO:0070995//NADPH oxidation	--
ENSG00000011007	10.015	9.706	10.039	7.964	8.823	8.218	1005	979	744	592	748	600	ELOA	elongin A [Source:HGNC Symbol;Acc:HGNC:11620]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070449//elongin complex;GO:0090734//site of DNA damage;GO:0110165//cellular anatomical entity	GO:0003746//translation elongation factor activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006414//translational elongation	--
ENSG00000011009	37.36	37.853	40.367	52.709	45.848	52.99	1234	1274	991	1302	1297	1273	LYPLA2	lysophospholipase 2 [Source:HGNC Symbol;Acc:HGNC:6738]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K06130	GO:0005737//cytoplasm;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0045296//cadherin binding;GO:0052689//carboxylic ester hydrolase activity	GO:0002084//protein depalmitoylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0007411//axon guidance;GO:0046464//acylglycerol catabolic process;GO:1905344//prostaglandin catabolic process	--
ENSG00000011021	7.717	8.341	7.909	9.053	9.045	10.011	891	968	675	773	884	842	CLCN6	chloride voltage-gated channel 6 [Source:HGNC Symbol;Acc:HGNC:2024]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005247//voltage-gated chloride channel activity;GO:0005524//ATP binding;GO:0015108//chloride transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0009612//response to mechanical stimulus;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000011028	24.489	24.817	24.139	22.579	23.908	26.541	2905	2959	2079	1984	2396	2289	MRC2	mannose receptor C type 2 [Source:HGNC Symbol;Acc:HGNC:16875]	Human Diseases;Cellular Processes	Infectious disease: bacterial;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome	K06560;K06560	GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0001649//osteoblast differentiation;GO:0006897//endocytosis;GO:0030574//collagen catabolic process	--
ENSG00000011052	3.522	2.576	3.749	2.684	5.127	2.555	72.34	55.68	58.64	42.1	91.73	40.2	NME1-NME2	NME1-NME2 readthrough [Source:HGNC Symbol;Acc:HGNC:33531]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0016310//phosphorylation;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000011083	0	0	0	0	0	0	0	0	0	0	0	0	SLC6A7	solute carrier family 6 member 7 [Source:HGNC Symbol;Acc:HGNC:11054]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K05040	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005298//proline:sodium symporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015293//symporter activity	GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0015824//proline transport;GO:0035524//proline transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport	--
ENSG00000011105	61.544	65.99	59.469	73.136	67.375	70.181	4665	4974	3500	3997	4390	3708	TSPAN9	tetraspanin 9 [Source:HGNC Symbol;Acc:HGNC:21640]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097197//tetraspanin-enriched microdomain	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000011114	8.49	8.155	7.238	6.98	12.663	7.448	1171	1141	741	685	853	774	BTBD7	BTB domain containing 7 [Source:HGNC Symbol;Acc:HGNC:18269]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0060693//regulation of branching involved in salivary gland morphogenesis;GO:0061138//morphogenesis of a branching epithelium	--
ENSG00000011132	5.251	5.577	5.25	5.653	6.451	6.273	237	253	175	189	246	206	APBA3	amyloid beta precursor protein binding family A member 3 [Source:HGNC Symbol;Acc:HGNC:580]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm	GO:0001540//amyloid-beta binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0001701//in utero embryonic development;GO:0007268//chemical synaptic transmission;GO:0010468//regulation of gene expression;GO:0015031//protein transport;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity	--
ENSG00000011143	7.39	5.855	6.347	6.262	6.303	6.287	248	226	164	165	206	168	MKS1	MKS transition zone complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7121]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	"GO:0001843//neural tube closure;GO:0003271//smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation;GO:0007368//determination of left/right symmetry;GO:0008589//regulation of smoothened signaling pathway;GO:0010669//epithelial structure maintenance;GO:0030030//cell projection organization;GO:0042733//embryonic digit morphogenesis;GO:0044458//motile cilium assembly;GO:0048706//embryonic skeletal system development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060271//cilium assembly;GO:0060322//head development;GO:0060411//cardiac septum morphogenesis;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061009//common bile duct development;GO:1901620//regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1905515//non-motile cilium assembly;GO:1990403//embryonic brain development;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000011198	11.475	9.87	9.258	7.475	9.088	9.66	639	538	395	320	422	409	ABHD5	"abhydrolase domain containing 5, lysophosphatidic acid acyltransferase [Source:HGNC Symbol;Acc:HGNC:21396]"	Organismal Systems	Endocrine system	ko04923//Regulation of lipolysis in adipocytes	K13699	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0010891//negative regulation of sequestering of triglyceride;GO:0010898//positive regulation of triglyceride catabolic process;GO:0030154//cell differentiation;GO:0050996//positive regulation of lipid catabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0055088//lipid homeostasis	--
ENSG00000011201	9.365	7.717	5.637	5.911	7.068	5.341	1217	1008	541	569	776	505	ANOS1	anosmin 1 [Source:HGNC Symbol;Acc:HGNC:6211]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031012//extracellular matrix	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity	GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030182//neuron differentiation	--
ENSG00000011243	24.986	24.118	26.741	25.727	23.944	29.752	1075	1043	852	822	870	931	AKAP8L	A-kinase anchoring protein 8 like [Source:HGNC Symbol;Acc:HGNC:29857]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:0016607//nuclear speck;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0016301//kinase activity;GO:0017151//DEAD/H-box RNA helicase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0007076//mitotic chromosome condensation;GO:0008380//RNA splicing;GO:0010793//regulation of mRNA export from nucleus;GO:0016310//phosphorylation;GO:0031065//positive regulation of histone deacetylation;GO:0033127//regulation of histone phosphorylation;GO:0044839//cell cycle G2/M phase transition;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051081//nuclear membrane disassembly	--
ENSG00000011258	4.738	3.934	4.266	3.456	3.713	4.541	504	431	344	282	337	356	MBTD1	mbt domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19866]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0000724//double-strand break repair via homologous recombination;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048706//embryonic skeletal system development;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000011260	14.469	12.503	15.797	14.121	13.202	12.433	563	489	454	407	434	352	UTP18	UTP18 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24274]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14553	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0032040//small-subunit processome;GO:0034388//Pwp2p-containing subcomplex of 90S preribosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing	--
ENSG00000011275	14.267	12.838	13.898	11.416	14.443	13.638	1568	1484	1131	991	1341	1015	RNF216	ring finger protein 216 [Source:HGNC Symbol;Acc:HGNC:21698]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0032648//regulation of interferon-beta production;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050691//regulation of defense response to virus by host;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000011295	14.95	13.942	15.374	11.685	15.016	13.05	824	786	601	479	687	529	TTC19	tetratricopeptide repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:26006]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005813//centrosome;GO:0016020//membrane;GO:0030496//midbody;GO:0070469//respirasome	GO:0005515//protein binding	GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0051301//cell division	--
ENSG00000011304	82.848	83.362	89.753	83.2	84.877	78.853	5220	5423	4234	4035	4648	3692	PTBP1	polypyrimidine tract binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9583]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008187//poly-pyrimidine tract binding;GO:0036002//pre-mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0033119//negative regulation of RNA splicing;GO:0035307//positive regulation of protein dephosphorylation;GO:0043484//regulation of RNA splicing;GO:0045595//regulation of cell differentiation;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0051148//negative regulation of muscle cell differentiation;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0075522//IRES-dependent viral translational initiation"	--
ENSG00000011332	0	0.25	0.142	0.221	0.396	0.442	0	12	5	8	9	8	DPF1	double PHD fingers 1 [Source:HGNC Symbol;Acc:HGNC:20225]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K22198;K22198	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071565//nBAF complex	GO:0003712//transcription coregulator activity;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045597//positive regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000011347	0.482	0.41	0.475	1.017	0.503	0.689	41	35	30	55	41	48	SYT7	synaptotagmin 7 [Source:HGNC Symbol;Acc:HGNC:11514]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030658//transport vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0032009//early phagosome;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0070382//exocytic vesicle;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0099056//integral component of presynaptic membrane	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0046872//metal ion binding"	GO:0001778//plasma membrane repair;GO:0006887//exocytosis;GO:0006909//phagocytosis;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0036465//synaptic vesicle recycling;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0046850//regulation of bone remodeling;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0050764//regulation of phagocytosis;GO:0050796//regulation of insulin secretion;GO:0070092//regulation of glucagon secretion;GO:0071277//cellular response to calcium ion;GO:0090119//vesicle-mediated cholesterol transport;GO:0090385//phagosome-lysosome fusion;GO:1990926//short-term synaptic potentiation;GO:1990927//calcium ion regulated lysosome exocytosis	--
ENSG00000011376	9.976	11.469	11.799	11.579	11.398	11.826	952	1072	844	785	904	819	LARS2	"leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01869	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004823//leucine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006429//leucyl-tRNA aminoacylation;GO:0032543//mitochondrial translation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000011405	13.079	7.347	7.026	4.757	6.671	7.386	2280	1269	874	616	967	920	PIK3C2A	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8971]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Infectious disease: bacterial;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05132//Salmonella infection;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00923;K00923;K00923;K00923	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0030276//clathrin binding;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0035091//phosphatidylinositol binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006887//exocytosis;GO:0006897//endocytosis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0010508//positive regulation of autophagy;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014829//vascular associated smooth muscle contraction;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048268//clathrin coat assembly;GO:0061024//membrane organization;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis	--
ENSG00000011422	2.829	2.921	1.695	3.59	3.378	2.975	65	69	36	75	81	62	PLAUR	"plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053]"	Human Diseases;Organismal Systems	Cancer: overview;Immune system	ko05205//Proteoglycans in cancer;ko04610//Complement and coagulation cascades	K03985;K03985	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0098637//protein complex involved in cell-matrix adhesion;GO:1905370//serine-type endopeptidase complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0030377//urokinase plasminogen activator receptor activity;GO:0038023//signaling receptor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0010755//regulation of plasminogen activation;GO:0030155//regulation of cell adhesion;GO:0030162//regulation of proteolysis;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0038195//urokinase plasminogen activator signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0051917//regulation of fibrinolysis;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000011426	1.486	1.422	1.147	0.741	0.981	0.603	114	109	65	49	64	39	ANLN	anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005826//actomyosin contractile ring;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0032059//bleb;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000281//mitotic cytokinesis;GO:0000915//actomyosin contractile ring assembly;GO:0000921//septin ring assembly;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007049//cell cycle;GO:0007096//regulation of exit from mitosis;GO:0031106//septin ring organization;GO:0051301//cell division;GO:0090521//glomerular visceral epithelial cell migration;GO:1904172//positive regulation of bleb assembly	--
ENSG00000011451	17.344	16.032	16.501	17.256	18.329	18.911	1712	1580	1229	1235	1567	1342	WIZ	WIZ zinc finger [Source:HGNC Symbol;Acc:HGNC:30917]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030496//midbody;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:1990226//histone methyltransferase binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0050821//protein stabilization	zf-C2H2
ENSG00000011454	17.489	17.539	18.992	12.443	14.559	16.691	1806	1747	1344	912	1251	1256	RABGAP1	RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005875//microtubule associated complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0031267//small GTPase binding	GO:0007049//cell cycle;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0090630//activation of GTPase activity	--
ENSG00000011465	61.179	65.756	21.772	13.34	22.881	19.508	1779	1935	354	301	585	430	DCN	decorin [Source:HGNC Symbol;Acc:HGNC:2705]	Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction	ko05205//Proteoglycans in cancer;ko04350//TGF-beta signaling pathway	K04660;K04660	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005539//glycosaminoglycan binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0050840//extracellular matrix binding	GO:0009887//animal organ morphogenesis;GO:0010508//positive regulation of autophagy;GO:0010596//negative regulation of endothelial cell migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016239//positive regulation of macroautophagy;GO:0016525//negative regulation of angiogenesis;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051901//positive regulation of mitochondrial depolarization;GO:0090141//positive regulation of mitochondrial fission;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway	--
ENSG00000011478	3.032	2.829	3.204	3.461	3.981	3.188	132	126	98	113	147	102	QPCTL	glutaminyl-peptide cyclotransferase like [Source:HGNC Symbol;Acc:HGNC:25952]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016603//glutaminyl-peptide cyclotransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	"GO:0017186//peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase"	--
ENSG00000011485	29.018	30.158	30.579	31.919	29.853	32.828	1285	1342	1002	1049	1119	1059	PPP5C	protein phosphatase 5 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9322]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04460	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0101031//chaperone complex;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0051879//Hsp90 protein binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0000165//MAPK cascade;GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006351//transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0010288//response to lead ion;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043278//response to morphine;GO:0070262//peptidyl-serine dephosphorylation;GO:1904550//response to arachidonic acid"	--
ENSG00000011523	8.494	7.387	6.931	7.633	7.446	7.61	1009	883	612	674	745	663	CEP68	centrosomal protein 68 [Source:HGNC Symbol;Acc:HGNC:29076]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding	GO:0007098//centrosome cycle;GO:0010457//centriole-centriole cohesion;GO:0033365//protein localization to organelle	--
ENSG00000011566	12.447	9.889	11.935	8.532	8.52	10.719	1092	812	653	536	640	624	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04406	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0009411//response to UV;GO:0016310//phosphorylation;GO:0034612//response to tumor necrosis factor;GO:0035556//intracellular signal transduction	--
ENSG00000011590	0.083	0.028	0	0.075	0	0	3	1	0	2	0	0	ZBTB32	zinc finger and BTB domain containing 32 [Source:HGNC Symbol;Acc:HGNC:16763]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000011600	0	0	0	0	0.298	0	0	0	0	0	3	0	TYROBP	transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04650//Natural killer cell mediated cytotoxicity;ko04380//Osteoclast differentiation	K07992;K07992	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0002222//stimulatory killer cell immunoglobulin-like receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002274//myeloid leukocyte activation;GO:0002282//microglial cell activation involved in immune response;GO:0002283//neutrophil activation involved in immune response;GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0030036//actin cytoskeleton organization;GO:0030316//osteoclast differentiation;GO:0030889//negative regulation of B cell proliferation;GO:0030900//forebrain development;GO:0032693//negative regulation of interleukin-10 production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0032930//positive regulation of superoxide anion generation;GO:0034241//positive regulation of macrophage fusion;GO:0035556//intracellular signal transduction;GO:0043277//apoptotic cell clearance;GO:0048678//response to axon injury;GO:0050821//protein stabilization;GO:0097190//apoptotic signaling pathway;GO:0110090//positive regulation of hippocampal neuron apoptotic process;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1901216//positive regulation of neuron death;GO:1902685//positive regulation of receptor localization to synapse;GO:1904151//positive regulation of microglial cell mediated cytotoxicity;GO:2000010//positive regulation of protein localization to cell surface;GO:2001206//positive regulation of osteoclast development	--
ENSG00000011638	5.879	6.975	6.329	6.442	7.789	5.985	201	210	143	157	174	134	LDAF1	lipid droplet assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30136]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0140042//lipid droplet formation	--
ENSG00000011677	0.145	0.209	0.321	0.124	0.233	0.217	11	16	10	7	15	12	GABRA3	gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000012048	1.572	1.113	0.961	0.373	0.709	0.469	78	52	28	13	30	24	BRCA1	BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100]	Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Signal transduction;Cancer: overview;Cancer: specific types;Folding, sorting and degradation;Drug resistance: antineoplastic;Replication and repair;Replication and repair"	ko04151//PI3K-Akt signaling pathway;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04120//Ubiquitin mediated proteolysis;ko01524//Platinum drug resistance;ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K10605;K10605;K10605;K10605;K10605;K10605;K10605	GO:0000151//ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000800//lateral element;GO:0000931//gamma-tubulin large complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0031436//BRCA1-BARD1 complex;GO:0032991//protein-containing complex;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0070531//BRCA1-A complex;GO:0070532//BRCA1-B complex;GO:0070533//BRCA1-C complex;GO:1990391//DNA repair complex;GO:1990904//ribonucleoprotein complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0070063//RNA polymerase binding	"GO:0000209//protein polyubiquitination;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006301//postreplication repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007098//centrosome cycle;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0010212//response to ionizing radiation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035066//positive regulation of histone acetylation;GO:0035067//negative regulation of histone acetylation;GO:0035518//histone H2A monoubiquitination;GO:0035825//homologous recombination;GO:0043009//chordate embryonic development;GO:0043627//response to estrogen;GO:0044030//regulation of DNA methylation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045739//positive regulation of DNA repair;GO:0045766//positive regulation of angiogenesis;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046600//negative regulation of centriole replication;GO:0050896//response to stimulus;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0051726//regulation of cell cycle;GO:0051865//protein autoubiquitination;GO:0070512//positive regulation of histone H4-K20 methylation;GO:0070537//histone H2A K63-linked deubiquitination;GO:0071356//cellular response to tumor necrosis factor;GO:0071479//cellular response to ionizing radiation;GO:0071681//cellular response to indole-3-methanol;GO:0085020//protein K6-linked ubiquitination;GO:0110025//DNA strand resection involved in replication fork processing;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000001//regulation of DNA damage checkpoint;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:2000620//positive regulation of histone H4-K16 acetylation"	--
ENSG00000012061	47.743	47.912	46.614	51.271	49.186	47.262	1334.29	1390.65	992.47	1106.92	1238.86	1010.8	ERCC1	"ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433]"	Human Diseases;Genetic Information Processing;Genetic Information Processing	Drug resistance: antineoplastic;Replication and repair;Replication and repair	ko01524//Platinum drug resistance;ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair	K10849;K10849;K10849	"GO:0000109//nucleotide-excision repair complex;GO:0000110//nucleotide-excision repair factor 1 complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0070522//ERCC4-ERCC1 complex"	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0001094//TFIID-class transcription factor complex binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0019904//protein domain specific binding;GO:1990599//3' overhang single-stranded DNA endodeoxyribonuclease activity;GO:1990841//promoter-specific chromatin binding	"GO:0000710//meiotic mismatch repair;GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006312//mitotic recombination;GO:0006949//syncytium formation;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0007584//response to nutrient;GO:0008283//cell population proliferation;GO:0008584//male gonad development;GO:0009650//UV protection;GO:0009744//response to sucrose;GO:0010165//response to X-ray;GO:0010259//multicellular organism aging;GO:0032205//negative regulation of telomere maintenance;GO:0033683//nucleotide-excision repair, DNA incision;GO:0035166//post-embryonic hemopoiesis;GO:0035264//multicellular organism growth;GO:0035902//response to immobilization stress;GO:0036297//interstrand cross-link repair;GO:0045190//isotype switching;GO:0046686//response to cadmium ion;GO:0048468//cell development;GO:0048477//oogenesis;GO:0048568//embryonic organ development;GO:0051276//chromosome organization;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0061819//telomeric DNA-containing double minutes formation;GO:0070914//UV-damage excision repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090399//replicative senescence;GO:0090656//t-circle formation;GO:1904431//positive regulation of t-circle formation;GO:1905765//negative regulation of protection from non-homologous end joining at telomere"	--
ENSG00000012124	0	0	0.024	0.564	0	0.085	0	0	1	8	0	2	CD22	CD22 molecule [Source:HGNC Symbol;Acc:HGNC:1643]	Organismal Systems;Environmental Information Processing;Organismal Systems	Immune system;Signaling molecules and interaction;Immune system	ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko04662//B cell receptor signaling pathway	K06467;K06467;K06467	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0001791//IgM binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0042609//CD4 receptor binding	GO:0002638//negative regulation of immunoglobulin production;GO:0007155//cell adhesion;GO:0030100//regulation of endocytosis;GO:0030888//regulation of B cell proliferation;GO:0042113//B cell activation;GO:0050776//regulation of immune response;GO:0050849//negative regulation of calcium-mediated signaling;GO:0050859//negative regulation of B cell receptor signaling pathway	--
ENSG00000012171	173.759	189.691	184.881	171.78	178.971	174.262	8794	9594	6910	6691	7702	6520	SEMA3B	semaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007267//cell-cell signaling;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0061643//chemorepulsion of axon;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000012174	14.65	13.042	11.701	12.004	12.552	12.817	1351	1209	797	820	978	860	MBTPS2	"membrane bound transcription factor peptidase, site 2 [Source:HGNC Symbol;Acc:HGNC:15455]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K07765	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034976//response to endoplasmic reticulum stress;GO:0036500//ATF6-mediated unfolded protein response;GO:0045540//regulation of cholesterol biosynthetic process;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0070977//bone maturation;GO:1905897//regulation of response to endoplasmic reticulum stress;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	--
ENSG00000012211	3.609	4.12	5.217	6.118	3.859	4.372	190.93	188.68	146.68	184.57	176.81	167.67	PRICKLE3	prickle planar cell polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:6645]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04511	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0030030//cell projection organization	--
ENSG00000012223	0	0	0	0	0.32	0	0	0	0	0	14	0	LTF	lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0032991//protein-containing complex;GO:0035580//specific granule lumen;GO:0042581//specific granule;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0097013//phagocytic vesicle lumen;GO:1904724//tertiary granule lumen	GO:0001530//lipopolysaccharide binding;GO:0003677//DNA binding;GO:0004252//serine-type endopeptidase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding	GO:0001503//ossification;GO:0001817//regulation of cytokine production;GO:0001895//retina homeostasis;GO:0002227//innate immune response in mucosa;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006959//humoral immune response;GO:0019731//antibacterial humoral response;GO:0019732//antifungal humoral response;GO:0031640//killing of cells of other organism;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032680//regulation of tumor necrosis factor production;GO:0032780//negative regulation of ATPase activity;GO:0033690//positive regulation of osteoblast proliferation;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044793//negative regulation by host of viral process;GO:0045071//negative regulation of viral genome replication;GO:0045669//positive regulation of osteoblast differentiation;GO:0048525//negative regulation of viral process;GO:0050829//defense response to Gram-negative bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051673//membrane disruption in other organism;GO:0055072//iron ion homeostasis;GO:0060349//bone morphogenesis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1900159//positive regulation of bone mineralization involved in bone maturation;GO:1900229//negative regulation of single-species biofilm formation in or on host organism;GO:1902732//positive regulation of chondrocyte proliferation;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:2000308//negative regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:2001205//negative regulation of osteoclast development	Others
ENSG00000012232	33.284	34.933	36.193	40.418	39.867	40.026	4361	4588	3492	3896	4401	3810	EXTL3	exostosin like glycosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:3518]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02370;K02370	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030307//positive regulation of cell growth	--
ENSG00000012504	1.046	0.945	0.655	0.562	0.281	0.206	37	36	18	17	7	5	NR1H4	nuclear receptor subfamily 1 group H member 4 [Source:HGNC Symbol;Acc:HGNC:7967]	Organismal Systems	Digestive system	ko04976//Bile secretion	K08537	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043235//receptor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016922//nuclear receptor binding;GO:0032052//bile acid binding;GO:0038181//bile acid receptor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:1902122//chenodeoxycholic acid binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001080//nitrogen catabolite activation of transcription from RNA polymerase II promoter;GO:0001678//cellular glucose homeostasis;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007043//cell-cell junction assembly;GO:0007219//Notch signaling pathway;GO:0008206//bile acid metabolic process;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032689//negative regulation of interferon-gamma production;GO:0032692//negative regulation of interleukin-1 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032740//positive regulation of interleukin-17 production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034255//regulation of urea metabolic process;GO:0034971//histone H3-R17 methylation;GO:0035356//cellular triglyceride homeostasis;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0038183//bile acid signaling pathway;GO:0038185//intracellular bile acid receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0055089//fatty acid homeostasis;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070328//triglyceride homeostasis;GO:0070857//regulation of bile acid biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071398//cellular response to fatty acid;GO:0071417//cellular response to organonitrogen compound;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0090181//regulation of cholesterol metabolic process;GO:1903413//cellular response to bile acid;GO:1904179//positive regulation of adipose tissue development;GO:1905695//positive regulation of phosphatidic acid biosynthetic process;GO:2000213//positive regulation of glutamate metabolic process;GO:2001250//positive regulation of ammonia assimilation cycle"	THR-like
ENSG00000012660	111.45	107.982	113.849	118.813	116.659	126.487	6411	6177	4756	4964	5589	5250	ELOVL5	ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10244;K10244;K10244;K10244	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0097447//dendritic tree	GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0045723//positive regulation of fatty acid biosynthetic process"	--
ENSG00000012779	3.134	3	2.593	1.55	2.183	1.892	162	155	98	60	95	71	ALOX5	arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435]	Metabolism;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Immune system;Nervous system;Infectious disease: parasitic;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04664//Fc epsilon RI signaling pathway;ko04726//Serotonergic synapse;ko05145//Toxoplasmosis;ko00590//Arachidonic acid metabolism;ko04913//Ovarian steroidogenesis	K00461;K00461;K00461;K00461;K00461;K00461	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005641//nuclear envelope lumen;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031965//nuclear membrane;GO:0034774//secretory granule lumen;GO:0048471//perinuclear region of cytoplasm;GO:1904813//ficolin-1-rich granule lumen	"GO:0004051//arachidonate 5-lipoxygenase activity;GO:0004052//arachidonate 12(S)-lipoxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016787//hydrolase activity;GO:0036403//arachidonate 8(S)-lipoxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001937//negative regulation of endothelial cell proliferation;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002540//leukotriene production involved in inflammatory response;GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006954//inflammatory response;GO:0006959//humoral immune response;GO:0016525//negative regulation of angiogenesis;GO:0019369//arachidonic acid metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0019372//lipoxygenase pathway;GO:0030501//positive regulation of bone mineralization;GO:0034440//lipid oxidation;GO:0036336//dendritic cell migration;GO:0042593//glucose homeostasis;GO:0042759//long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0045598//regulation of fat cell differentiation;GO:0050727//regulation of inflammatory response;GO:0050728//negative regulation of inflammatory response;GO:0050796//regulation of insulin secretion;GO:0051122//hepoxilin biosynthetic process;GO:0061044//negative regulation of vascular wound healing;GO:0061045//negative regulation of wound healing;GO:0106014//regulation of inflammatory response to wounding;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1900407//regulation of cellular response to oxidative stress;GO:1901753//leukotriene A4 biosynthetic process;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1903573//negative regulation of response to endoplasmic reticulum stress;GO:1903671//negative regulation of sprouting angiogenesis;GO:1904999//positive regulation of leukocyte adhesion to arterial endothelial cell;GO:2001301//lipoxin biosynthetic process	--
ENSG00000012817	16.117	15.651	21.31	17.946	16.586	15.862	1715	1687	1406	1339	1530	1326	KDM5D	lysine demethylase 5D [Source:HGNC Symbol;Acc:HGNC:11115]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0034647//histone H3-tri/di/monomethyl-lysine-4 demethylase activity;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0051213//dioxygenase activity	"GO:0002457//T cell antigen processing and presentation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0034720//histone H3-K4 demethylation;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0060765//regulation of androgen receptor signaling pathway;GO:0070076//histone lysine demethylation"	--
ENSG00000012822	30.067	34.237	37.916	33.889	35.896	31.844	1799	2050	1553	1596	1809	1546	CALCOCO1	calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0030374//nuclear receptor coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070016//armadillo repeat domain binding	"GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000012963	10.231	10.925	10.28	10.635	9.65	9.526	706	740	508	497	544	487	UBR7	ubiquitin protein ligase E3 component n-recognin 7 [Source:HGNC Symbol;Acc:HGNC:20344]	-	-	-	-	-	GO:0003674//molecular_function;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008150//biological_process;GO:0016567//protein ubiquitination	--
ENSG00000012983	9.365	5.963	6.604	4.424	5.235	6.175	798	522	429	270	375	398	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6867]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000013016	21.703	23.868	19.482	19.222	20.307	18.91	2172	2401	1440	1425	1717	1377	EHD3	EH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:3244]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12476	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0020018//ciliary pocket membrane;GO:0030139//endocytic vesicle;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0060170//ciliary membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0001881//receptor recycling;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030030//cell projection organization;GO:0032456//endocytic recycling;GO:0034498//early endosome to Golgi transport;GO:0051260//protein homooligomerization;GO:0055117//regulation of cardiac muscle contraction;GO:0060271//cilium assembly;GO:0072659//protein localization to plasma membrane;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0090160//Golgi to lysosome transport;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903358//regulation of Golgi organization;GO:1903779//regulation of cardiac conduction	--
ENSG00000013275	31.957	36.232	34.537	33.248	38.844	35.255	1149	1277	928	896	1180	931	PSMC4	"proteasome 26S subunit, ATPase 4 [Source:HGNC Symbol;Acc:HGNC:9551]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03063;K03063;K03063;K03063;K03063;K03063;K03063;K03063;K03063	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0043229//intracellular organelle"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0036402//proteasome-activating activity	GO:0001824//blastocyst development;GO:0006261//DNA-dependent DNA replication;GO:0006508//proteolysis;GO:0030163//protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0044085//cellular component biogenesis;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000013288	23.74	27.226	24.868	20.943	21.793	19.001	2495	2809	1919	1633	1967	1456	MAN2B2	mannosidase alpha class 2B member 2 [Source:HGNC Symbol;Acc:HGNC:29623]	Metabolism	Glycan biosynthesis and metabolism	ko00511//Other glycan degradation	K12312	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0008152//metabolic process	--
ENSG00000013293	0	0	0	0	0	0	0	0	0	0	0	0	SLC7A14	solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport	--
ENSG00000013297	0.315	0.296	0.047	0.132	0.041	0.264	18	17	2	5.59	2	11	CLDN11	claudin 11 [Source:HGNC Symbol;Acc:HGNC:8514]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005811//lipid droplet;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0045178//basal part of cell;GO:0070160//tight junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007283//spermatogenesis;GO:0008366//axon ensheathment;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly;GO:0120192//tight junction assembly	--
ENSG00000013306	59.761	62.515	67.482	82.924	75.527	70.29	1940	2045	1636	2004	2057	1647	SLC25A39	solute carrier family 25 member 39 [Source:HGNC Symbol;Acc:HGNC:24279]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006783//heme biosynthetic process;GO:0055085//transmembrane transport;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000013364	59.186	58.878	60.052	57.133	60.691	55.18	2827	2823	2138	2111	2444	1893	MVP	major vault protein [Source:HGNC Symbol;Acc:HGNC:7531]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding	GO:0015031//protein transport;GO:0031953//negative regulation of protein autophosphorylation;GO:0038127//ERBB signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0051028//mRNA transport;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000013374	24.273	22.805	21.388	18.004	21.005	19.969	818	845	582	498	597	549	NUB1	negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:2000058//regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000013375	11.755	9.398	9.819	7.681	10.422	7.909	1031.84	845.94	621.79	443.04	591.71	519.36	PGM3	phosphoglucomutase 3 [Source:HGNC Symbol;Acc:HGNC:8907]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01836;K01836	GO:0005575//cellular_component;GO:0005829//cytosol	"GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004610//phosphoacetylglucosamine mutase activity;GO:0004614//phosphoglucomutase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006041//glucosamine metabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007283//spermatogenesis;GO:0019255//glucose 1-phosphate metabolic process;GO:0030097//hemopoiesis;GO:0071704//organic substance metabolic process	--
ENSG00000013392	4.017	3.754	4.122	3.229	3.497	4.026	314	295	238	187	231	229	RWDD2A	RWD domain containing 2A [Source:HGNC Symbol;Acc:HGNC:21385]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000013441	13.891	13.272	14.373	8.018	10.628	13.675	514	479	380	216	324	358	CLK1	CDC like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2068]	Human Diseases	Infectious disease: bacterial	ko05134//Legionellosis	K23561	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043484//regulation of RNA splicing;GO:0046777//protein autophosphorylation	--
ENSG00000013503	7.515	6.882	6.759	7.951	8.023	7.239	652	600	432	511	587	457	POLR3B	RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03021;K03021	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0032549//ribonucleoside binding;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006351//transcription, DNA-templated;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus"	--
ENSG00000013523	12.459	12.693	11.851	14.581	12.401	14.231	1087	1025	848	903	932	889	ANGEL1	angel homolog 1 [Source:HGNC Symbol;Acc:HGNC:19961]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0000175//3'-5'-exoribonuclease activity;GO:0003824//catalytic activity;GO:0008190//eukaryotic initiation factor 4E binding;GO:0019904//protein domain specific binding	"GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000013561	25.149	29.179	29.724	31.467	30.243	23.645	1046	1131	770	825	896.24	724	RNF14	ring finger protein 14 [Source:HGNC Symbol;Acc:HGNC:10058]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0016567//protein ubiquitination;GO:0030521//androgen receptor signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060765//regulation of androgen receptor signaling pathway"	--
ENSG00000013563	21.152	18.393	18.755	16.763	16.13	16.101	766.26	695.56	505.23	454.52	517.38	429.97	DNASE1L1	deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0035580//specific granule lumen	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004530//deoxyribonuclease I activity;GO:0004536//deoxyribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006259//DNA metabolic process;GO:0006308//DNA catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000013573	1.778	3.247	3.255	2.283	2.245	1.87	114	147	114	97	130	103	DDX11	DEAD/H-box helicase 11 [Source:HGNC Symbol;Acc:HGNC:2736]	-	-	-	-	GO:0000785//chromatin;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0031390//Ctf18 RFC-like complex;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0003688//DNA replication origin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008186//ATP-dependent activity, acting on RNA;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0043139//5'-3' DNA helicase activity;GO:0045142//triplex DNA binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051880//G-quadruplex DNA binding"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007062//sister chromatid cohesion;GO:0031297//replication fork processing;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0032091//negative regulation of protein binding;GO:0032508//DNA duplex unwinding;GO:0034085//establishment of sister chromatid cohesion;GO:0035563//positive regulation of chromatin binding;GO:0044806//G-quadruplex DNA unwinding;GO:0045876//positive regulation of sister chromatid cohesion;GO:0072711//cellular response to hydroxyurea;GO:0072719//cellular response to cisplatin;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1904976//cellular response to bleomycin;GO:1990700//nucleolar chromatin organization;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000013583	36.474	37.223	33.005	44.027	36.058	41.03	879	902	586	784	730	719	HEBP1	heme binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17176]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0020037//heme binding	GO:0007623//circadian rhythm	--
ENSG00000013588	12.269	15.002	13.088	12.433	14.416	12.257	920	978	660	631	819	658	GPRC5A	G protein-coupled receptor class C group 5 member A [Source:HGNC Symbol;Acc:HGNC:9836]	-	-	-	-	GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0045296//cadherin binding	GO:0007165//signal transduction;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032147//activation of protein kinase activity	--
ENSG00000013619	6.842	6.632	6.547	5.735	5.881	5.331	669	661	469	418	488	384	MAMLD1	mastermind like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:2568]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0016604//nuclear body	GO:0003674//molecular_function	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008584//male gonad development	--
ENSG00000013725	0.076	0.016	0.06	0.043	0.019	0	2	1	3	2	1	0	CD6	CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06456	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0042101//T cell receptor complex;GO:0044214//spanning component of plasma membrane	GO:0001530//lipopolysaccharide binding;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0070891//lipoteichoic acid binding	GO:0001771//immunological synapse formation;GO:0001934//positive regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0006897//endocytosis;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0042102//positive regulation of T cell proliferation;GO:0045087//innate immune response;GO:1900017//positive regulation of cytokine production involved in inflammatory response	--
ENSG00000013810	2.547	2.843	2.778	3.744	3.216	3.258	147	164	121	156	160	139	TACC3	transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0072686//mitotic spindle	GO:0005515//protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0008283//cell population proliferation;GO:0021987//cerebral cortex development;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:1902850//microtubule cytoskeleton organization involved in mitosis	--
ENSG00000014123	4.689	3.904	3.815	2.726	3.808	3.12	411	344	247	177	282	199	UFL1	UFM1 specific ligase 1 [Source:HGNC Symbol;Acc:HGNC:23039]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0035861//site of double-strand break;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0061666//UFM1 ligase activity;GO:0071568//UFM1 transferase activity	GO:0001649//osteoblast differentiation;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016570//histone modification;GO:0030218//erythrocyte differentiation;GO:0031397//negative regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032880//regulation of protein localization;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0060218//hematopoietic stem cell differentiation;GO:0060252//positive regulation of glial cell proliferation;GO:0061709//reticulophagy;GO:0071569//protein ufmylation;GO:1902065//response to L-glutamate;GO:1903895//negative regulation of IRE1-mediated unfolded protein response;GO:1990592//protein K69-linked ufmylation	--
ENSG00000014138	2.223	4.361	4.291	2.194	2.553	1.688	134.46	194.93	105.15	112.28	125.69	90.27	POLA2	"DNA polymerase alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073]"	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02321	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005658//alpha DNA polymerase:primase complex;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0006260//DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006270//DNA replication initiation"	--
ENSG00000014164	6.782	7.495	7.386	8.599	8.551	8.126	460	511	370	432	490	401	ZC3H3	zinc finger CCCH-type containing 3 [Source:HGNC Symbol;Acc:HGNC:28972]	-	-	-	-	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0070412//R-SMAD binding	GO:0031124//mRNA 3'-end processing;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0051028//mRNA transport;GO:1900363//regulation of mRNA polyadenylation	--
ENSG00000014216	47.781	49.558	47.472	53.437	49.029	42.856	2606	2874	2049	2192	2412	1719	CAPN1	calpain 1 [Source:HGNC Symbol;Acc:HGNC:1476]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Cell growth and death"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05131//Shigellosis;ko04141//Protein processing in endoplasmic reticulum;ko04217//Necroptosis;ko04218//Cellular senescence;ko04210//Apoptosis	K01367;K01367;K01367;K01367;K01367;K01367;K01367	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0110158//calpain complex;GO:1904813//ficolin-1-rich granule lumen	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008284//positive regulation of cell population proliferation;GO:0016241//regulation of macroautophagy;GO:0032801//receptor catabolic process;GO:0050790//regulation of catalytic activity;GO:0060056//mammary gland involution;GO:0097264//self proteolysis;GO:2000310//regulation of NMDA receptor activity	--
ENSG00000014257	0.354	0.364	0.409	0.021	0.234	0.074	15	13	13	1	9	2	ACP3	acid phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:125]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030175//filopodium;GO:0035577//azurophil granule membrane;GO:0070062//extracellular exosome	GO:0003993//acid phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042131//thiamine phosphate phosphatase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0052642//lysophosphatidic acid phosphatase activity	GO:0006144//purine nucleobase metabolic process;GO:0006629//lipid metabolic process;GO:0006772//thiamine metabolic process;GO:0007040//lysosome organization;GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046085//adenosine metabolic process;GO:0051930//regulation of sensory perception of pain;GO:0060168//positive regulation of adenosine receptor signaling pathway	--
ENSG00000014641	76.94	77.991	80.113	79.69	76.405	82.024	2072	2116	1592	1595	1747	1608	MDH1	malate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6970]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Excretory system	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle);ko04964//Proximal tubule bicarbonate reclamation	K00025;K00025;K00025;K00025;K00025;K00025;K00025	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004470//malic enzyme activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016615//malate dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030060//L-malate dehydrogenase activity;GO:0047860//diiodophenylpyruvate reductase activity"	GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006108//malate metabolic process;GO:0006734//NADH metabolic process;GO:0019752//carboxylic acid metabolic process	--
ENSG00000014824	27.946	25.778	24.236	19.073	20.656	22.613	2167	1951	1356	1089	1244	1210	SLC30A9	solute carrier family 30 member 9 [Source:HGNC Symbol;Acc:HGNC:1329]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0003682//chromatin binding;GO:0008324//cation transmembrane transporter activity;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity	GO:0006289//nucleotide-excision repair;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000014914	1.986	1.908	2.046	1.26	1.065	1.913	117	113	89	55	53	82	MTMR11	myotubularin related protein 11 [Source:HGNC Symbol;Acc:HGNC:24307]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0004438//phosphatidylinositol-3-phosphatase activity	GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000014919	9.961	9.489	10.004	8.374	9.302	10.22	840.61	832.18	629	545.01	669.19	615.35	COX15	cytochrome c oxidase assembly homolog COX15 [Source:HGNC Symbol;Acc:HGNC:2263]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation;ko00860//Porphyrin metabolism	K02259;K02259;K02259;K02259	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070069//cytochrome complex	"GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0020037//heme binding;GO:0060090//molecular adaptor activity"	"GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0006783//heme biosynthetic process;GO:0006784//heme A biosynthetic process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008535//respiratory chain complex IV assembly;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000015133	1.142	0.992	0.756	0.754	0.936	0.723	143	147	83	68	119	82	CCDC88C	coiled-coil domain containing 88C [Source:HGNC Symbol;Acc:HGNC:19967]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0030054//cell junction	GO:0001965//G-protein alpha-subunit binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0051959//dynein light intermediate chain binding	GO:0001932//regulation of protein phosphorylation;GO:0003383//apical constriction;GO:0007264//small GTPase mediated signal transduction;GO:0016055//Wnt signaling pathway;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031098//stress-activated protein kinase signaling cascade;GO:0031122//cytoplasmic microtubule organization;GO:0031648//protein destabilization;GO:0035567//non-canonical Wnt signaling pathway;GO:0050790//regulation of catalytic activity;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000015153	7.016	5.987	4.944	5.152	4.042	5.514	298	256	172	165	152	184	YAF2	YY1 associated factor 2 [Source:HGNC Symbol;Acc:HGNC:17363]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000015171	32.667	30.156	30.334	22.288	25.272	26.985	2679	2481	1835	1342	1796	1595	ZMYND11	zinc finger MYND-type containing 11 [Source:HGNC Symbol;Acc:HGNC:16966]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046329//negative regulation of JNK cascade;GO:0051607//defense response to virus;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000015285	0.053	0.36	0.143	0.036	0.156	0	2	7	4	1	5	0	WAS	WASP actin nucleation promoting factor [Source:HGNC Symbol;Acc:HGNC:12731]	Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: bacterial;Immune system;Cellular community - eukaryotes;Immune system;Cancer: overview;Cellular community - eukaryotes	ko05135//Yersinia infection;ko04062//Chemokine signaling pathway;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko04520//Adherens junction	K05747;K05747;K05747;K05747;K05747;K05747	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0012506//vesicle membrane;GO:0015629//actin cytoskeleton;GO:0035861//site of double-strand break;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0030695//GTPase regulator activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding	GO:0002625//regulation of T cell antigen processing and presentation;GO:0006952//defense response;GO:0006955//immune response;GO:0007015//actin filament organization;GO:0007596//blood coagulation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008154//actin polymerization or depolymerization;GO:0008544//epidermis development;GO:0010591//regulation of lamellipodium assembly;GO:0016197//endosomal transport;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030048//actin filament-based movement;GO:0032488//Cdc42 protein signal transduction;GO:0042110//T cell activation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051492//regulation of stress fiber assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0065003//protein-containing complex assembly;GO:0071346//cellular response to interferon-gamma;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000146//negative regulation of cell motility;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000015413	0	0	0	0	0	0	0	0	0	0	0	0	DPEP1	dipeptidase 1 [Source:HGNC Symbol;Acc:HGNC:3002]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0008800//beta-lactamase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0034235//GPI anchor binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity;GO:0072341//modified amino acid binding	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006749//glutathione metabolic process;GO:0006751//glutathione catabolic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0016999//antibiotic metabolic process;GO:0030336//negative regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050667//homocysteine metabolic process;GO:0071277//cellular response to calcium ion;GO:0071466//cellular response to xenobiotic stimulus;GO:0071732//cellular response to nitric oxide;GO:0072340//cellular lactam catabolic process	--
ENSG00000015475	10.038	9.544	9.441	9.203	8.925	10.545	431	369	305	280	315	337	BID	BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Cardiovascular disease;Signal transduction;Drug resistance: antineoplastic;Cell growth and death;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04210//Apoptosis;ko05416//Viral myocarditis;ko04071//Sphingolipid signaling pathway;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04215//Apoptosis - multiple species	K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726;K04726	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0032592//integral component of mitochondrial membrane	GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0001836//release of cytochrome c from mitochondria;GO:0006626//protein targeting to mitochondrion;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008637//apoptotic mitochondrial changes;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0012501//programmed cell death;GO:0031334//positive regulation of protein-containing complex assembly;GO:0042127//regulation of cell population proliferation;GO:0042770//signal transduction in response to DNA damage;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0051402//neuron apoptotic process;GO:0065003//protein-containing complex assembly;GO:0090150//establishment of protein localization to membrane;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097284//hepatocyte apoptotic process;GO:0097345//mitochondrial outer membrane permeabilization;GO:0097435//supramolecular fiber organization;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000015479	110.961	89.458	91.322	64.115	61.291	73.947	5829.45	4733.6	3403.32	2603.08	2867.14	2873.98	MATR3	matrin 3 [Source:HGNC Symbol;Acc:HGNC:6912]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K13213	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016363//nuclear matrix	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035198//miRNA binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0003170//heart valve development;GO:0003281//ventricular septum development;GO:0010608//posttranscriptional regulation of gene expression;GO:0045087//innate immune response	--
ENSG00000015520	0	0	0	0	0	0	0	0	0	0	0	0	NPC1L1	NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898]	Organismal Systems	Digestive system	ko04975//Fat digestion and absorption	K14461	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0044214//spanning component of plasma membrane	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0031489//myosin V binding;GO:1901363//heterocyclic compound binding	GO:0006629//lipid metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0014850//response to muscle activity;GO:0030299//intestinal cholesterol absorption;GO:0030301//cholesterol transport;GO:0042157//lipoprotein metabolic process;GO:0071501//cellular response to sterol depletion	--
ENSG00000015532	12.444	11.051	13.401	13.046	11.572	13.552	790	767	694	640	694	652	XYLT2	xylosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:15517]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00771;K00771;K00771	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000287//magnesium ion binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0030158//protein xylosyltransferase activity;GO:0046872//metal ion binding	GO:0006024//glycosaminoglycan biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0019538//protein metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030210//heparin biosynthetic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process	--
ENSG00000015568	6.805	0.291	1.385	1.378	3.519	3.07	925.38	20.84	79.04	146.6	434.64	323.69	RGPD5	RANBP2 like and GRIP domain containing 5 [Source:HGNC Symbol;Acc:HGNC:32418]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000015592	0	0	0	0	0	0	0	0	0	0	0	0	STMN4	stathmin 4 [Source:HGNC Symbol;Acc:HGNC:16078]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0015631//tubulin binding	GO:0007019//microtubule depolymerization;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031175//neuron projection development	--
ENSG00000015676	10.985	11.185	11.86	11.056	12.881	11.255	1831	1874	1460	1365	1814	1365	NUDCD3	NudC domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22208]	-	-	-	-	GO:0005737//cytoplasm;GO:0005868//cytoplasmic dynein complex	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0060271//cilium assembly;GO:1905793//protein localization to pericentriolar material	--
ENSG00000016082	0	0	0	0	0	0	0	0	0	0	0	0	ISL1	ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09370	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030331//estrogen receptor binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001755//neural crest cell migration;GO:0003007//heart morphogenesis;GO:0003139//secondary heart field specification;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021522//spinal cord motor neuron differentiation;GO:0021524//visceral motor neuron differentiation;GO:0021559//trigeminal nerve development;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0031016//pancreas development;GO:0031103//axon regeneration;GO:0031290//retinal ganglion cell axon guidance;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032024//positive regulation of insulin secretion;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035066//positive regulation of histone acetylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043388//positive regulation of DNA binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048762//mesenchymal cell differentiation;GO:0048880//sensory system development;GO:0048935//peripheral nervous system neuron development;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060037//pharyngeal system development;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0060384//innervation;GO:0060413//atrial septum morphogenesis;GO:0060913//cardiac cell fate determination;GO:0060931//sinoatrial node cell development;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1901258//positive regulation of macrophage colony-stimulating factor production"	Homeobox
ENSG00000016391	10.175	10.062	11.187	7.986	14.727	15.452	1488.72	1296.03	1141	899	1077.98	1213	CHDH	choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism"	K00108;K00108	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0005515//protein binding;GO:0008812//choline dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0050660//flavin adenine dinucleotide binding"	GO:0019285//glycine betaine biosynthetic process from choline;GO:0042426//choline catabolic process	--
ENSG00000016402	0.736	0.537	0.497	0.67	0.358	0.666	41	39	26	34	19	34	IL20RA	interleukin 20 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6003]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05136;K05136;K05136	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0042015//interleukin-20 binding	GO:0019221//cytokine-mediated signaling pathway;GO:0045124//regulation of bone resorption;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000016490	0	0	0	0	0.038	0.088	0	0	0	0	2	4	CLCA1	chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015]	Organismal Systems;Organismal Systems	Digestive system;Endocrine system	ko04972//Pancreatic secretion;ko04924//Renin secretion	K05027;K05027	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0042589//zymogen granule membrane	GO:0004222//metalloendopeptidase activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0071456//cellular response to hypoxia	--
ENSG00000016602	0	0	0	0	0	0	0	0	0	0	0	0	CLCA4	chloride channel accessory 4 [Source:HGNC Symbol;Acc:HGNC:2018]	Organismal Systems;Organismal Systems	Digestive system;Endocrine system	ko04972//Pancreatic secretion;ko04924//Renin secretion	K05030;K05030	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport	--
ENSG00000016864	35.387	32.079	31.2	29.778	25.305	32.135	998	992	687	632	686	690	GLT8D1	glycosyltransferase 8 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24870]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	-	--
ENSG00000017260	67	61.048	61.526	49.864	53.438	56.126	5314.92	5037.92	3641	2995	3500	3282	ATP2C1	ATPase secretory pathway Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:13211]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0033106//cis-Golgi network membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0015662//P-type ion transporter activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140613//P-type manganese transporter activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0008544//epidermis development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0031532//actin cytoskeleton reorganization;GO:0032468//Golgi calcium ion homeostasis;GO:0032472//Golgi calcium ion transport;GO:0034220//ion transmembrane transport;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070588//calcium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0098629//trans-Golgi network membrane organization	--
ENSG00000017427	0.508	0.167	0.595	0.368	0.314	0.43	41	25	18	17	40	26	IGF1	insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Cell growth and death;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Aging;Cardiovascular disease;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cell growth and death;Aging;Nervous system;Endocrine system;Excretory system	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04150//mTOR signaling pathway;ko05224//Breast cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko04115//p53 signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko04960//Aldosterone-regulated sodium reabsorption"	K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459;K05459	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016942//insulin-like growth factor binding protein complex;GO:0031093//platelet alpha granule lumen;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0042567//insulin-like growth factor ternary complex;GO:0070382//exocytic vesicle	GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005178//integrin binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0001501//skeletal system development;GO:0001775//cell activation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0007517//muscle organ development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009408//response to heat;GO:0009441//glycolate metabolic process;GO:0010468//regulation of gene expression;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0014896//muscle hypertrophy;GO:0014904//myotube cell development;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030166//proteoglycan biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0032148//activation of protein kinase B activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0035630//bone mineralization involved in bone maturation;GO:0040014//regulation of multicellular organism growth;GO:0042060//wound healing;GO:0042104//positive regulation of activated T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0043410//positive regulation of MAPK cascade;GO:0043491//protein kinase B signaling;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045445//myoblast differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045821//positive regulation of glycolytic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050821//protein stabilization;GO:0051450//myoblast proliferation;GO:0060283//negative regulation of oocyte development;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0150079//negative regulation of neuroinflammatory response;GO:1902430//negative regulation of amyloid-beta formation;GO:1904075//positive regulation of trophectodermal cell proliferation;GO:1904646//cellular response to amyloid-beta;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905460//negative regulation of vascular associated smooth muscle cell apoptotic process;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000017483	1.221	1.258	1.59	1.516	1.447	1.286	30	41	20	28	33	31	SLC38A5	solute carrier family 38 member 5 [Source:HGNC Symbol;Acc:HGNC:18070]	Organismal Systems	Nervous system	ko04727//GABAergic synapse	K14992	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005290//L-histidine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015182//L-asparagine transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0022858//alanine transmembrane transporter activity;GO:0022889//serine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0006867//asparagine transport;GO:0006868//glutamine transport;GO:0015816//glycine transport;GO:0015825//L-serine transport;GO:0032329//serine transport;GO:0089709//L-histidine transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1903713//asparagine transmembrane transport;GO:1904557//L-alanine transmembrane transport	--
ENSG00000017797	17.947	17.606	16.21	14.017	15.079	15.836	1604	1604	1085	913	1156	998	RALBP1	ralA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9841]	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko05212//Pancreatic cancer	K08773;K08773;K08773	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0022857//transmembrane transporter activity;GO:0031267//small GTPase binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0055085//transmembrane transport;GO:0090141//positive regulation of mitochondrial fission;GO:1900753//doxorubicin transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000018189	12.497	11.261	10.362	8.327	10.823	11.323	881	680	502	381	549	521	RUFY3	RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007015//actin filament organization;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0045773//positive regulation of axon extension;GO:0050770//regulation of axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0090316//positive regulation of intracellular protein transport;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000018236	90.584	75.2	76.001	67.543	72.385	74.13	8304	6802	5215	4691	5680	5120	CNTN1	contactin 1 [Source:HGNC Symbol;Acc:HGNC:2171]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06759	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0099025//anchored component of postsynaptic membrane;GO:0099026//anchored component of presynaptic membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007626//locomotory behavior;GO:0010628//positive regulation of gene expression;GO:0010765//positive regulation of sodium ion transport;GO:0010976//positive regulation of neuron projection development;GO:0021549//cerebellum development;GO:0031175//neuron projection development;GO:0032289//central nervous system myelin formation;GO:0042552//myelination;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0098609//cell-cell adhesion	--
ENSG00000018280	0.027	0.093	0	0.018	0	0	2	7	0	1	0	0	SLC11A1	solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12347	GO:0005575//cellular_component;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031902//late endosome membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0003674//molecular_function;GO:0005381//iron ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0015086//cadmium ion transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046873//metal ion transmembrane transporter activity;GO:0046915//transition metal ion transmembrane transporter activity;GO:0051139//metal ion:proton antiporter activity	GO:0001818//negative regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0002309//T cell proliferation involved in immune response;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006828//manganese ion transport;GO:0006876//cellular cadmium ion homeostasis;GO:0006879//cellular iron ion homeostasis;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007035//vacuolar acidification;GO:0009617//response to bacterium;GO:0010628//positive regulation of gene expression;GO:0015707//nitrite transport;GO:0019730//antimicrobial humoral response;GO:0030001//metal ion transport;GO:0032147//activation of protein kinase activity;GO:0032496//response to lipopolysaccharide;GO:0032729//positive regulation of interferon-gamma production;GO:0034341//response to interferon-gamma;GO:0034755//iron ion transmembrane transport;GO:0042060//wound healing;GO:0042116//macrophage activation;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0045342//MHC class II biosynthetic process;GO:0045454//cell redox homeostasis;GO:0045730//respiratory burst;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048002//antigen processing and presentation of peptide antigen;GO:0048255//mRNA stabilization;GO:0050766//positive regulation of phagocytosis;GO:0050829//defense response to Gram-negative bacterium;GO:0055072//iron ion homeostasis;GO:0060586//multicellular organismal iron ion homeostasis;GO:0070574//cadmium ion transmembrane transport;GO:0070839//metal ion export;GO:0071421//manganese ion transmembrane transport;GO:1903826//arginine transmembrane transport	--
ENSG00000018408	60.85	51.825	53.173	46.144	48.131	45.238	6300	5274	4103	3233	3623	3424	WWTR1	WW domain containing transcription regulator 1 [Source:HGNC Symbol;Acc:HGNC:24042]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16820;K16820	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body	GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0001894//tissue homeostasis;GO:0001933//negative regulation of protein phosphorylation;GO:0003015//heart process;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0008284//positive regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016567//protein ubiquitination;GO:0017145//stem cell division;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032835//glomerulus development;GO:0035264//multicellular organism growth;GO:0035329//hippo signaling;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048762//mesenchymal cell differentiation;GO:0060271//cilium assembly;GO:0060390//regulation of SMAD protein signal transduction;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060993//kidney morphogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900182//positive regulation of protein localization to nucleus"	--
ENSG00000018510	12.147	11.22	10.712	10.969	11.536	10.306	1059	907	653	624	649	594	AGPS	alkylglycerone phosphate synthase [Source:HGNC Symbol;Acc:HGNC:327]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00565//Ether lipid metabolism	K00803;K00803;K00803	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008609//alkylglycerone-phosphate synthase activity;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding	GO:0006629//lipid metabolic process;GO:0008610//lipid biosynthetic process;GO:0008611//ether lipid biosynthetic process	--
ENSG00000018610	8.156	9.395	10.006	8.246	8.591	7.138	352	403	307	261	297	232	STEEP1	STING1 ER exit protein 1 [Source:HGNC Symbol;Acc:HGNC:26239]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0044297//cell body	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0090158//endoplasmic reticulum membrane organization	--
ENSG00000018625	2.067	2.753	2.462	1.821	2.919	1.247	233	312	205	142	278	100	ATP1A2	ATPase Na+/K+ transporting subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:800]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005901//caveola;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0031090//organelle membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0016791//phosphatase activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030955//potassium ion binding;GO:0031402//sodium ion binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:1990239//steroid hormone binding	"GO:0001504//neurotransmitter uptake;GO:0001662//behavioral fear response;GO:0002026//regulation of the force of heart contraction;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0006937//regulation of muscle contraction;GO:0006940//regulation of smooth muscle contraction;GO:0006942//regulation of striated muscle contraction;GO:0008217//regulation of blood pressure;GO:0008344//adult locomotory behavior;GO:0008542//visual learning;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0010996//response to auditory stimulus;GO:0016311//dephosphorylation;GO:0019229//regulation of vasoconstriction;GO:0021764//amygdala development;GO:0021989//olfactory cortex development;GO:0030007//cellular potassium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0035641//locomotory exploration behavior;GO:0035725//sodium ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0040011//locomotion;GO:0045822//negative regulation of heart contraction;GO:0045823//positive regulation of heart contraction;GO:0045988//negative regulation of striated muscle contraction;GO:0046034//ATP metabolic process;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051946//regulation of glutamate uptake involved in transmission of nerve impulse;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0055119//relaxation of cardiac muscle;GO:0060048//cardiac muscle contraction;GO:0071260//cellular response to mechanical stimulus;GO:0071383//cellular response to steroid hormone stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086009//membrane repolarization;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0098655//cation transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1902600//proton transmembrane transport;GO:1903170//negative regulation of calcium ion transmembrane transport;GO:1903280//negative regulation of calcium:sodium antiporter activity;GO:1903416//response to glycoside;GO:1990573//potassium ion import across plasma membrane"	--
ENSG00000018699	5.642	6.679	4.701	6.13	4.821	5.369	338	318	208	272	244	234	TTC27	tetratricopeptide repeat domain 27 [Source:HGNC Symbol;Acc:HGNC:25986]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000018869	1.331	1.812	1.325	2.36	0.809	1.024	51	46	33	50	36	38	ZNF582	zinc finger protein 582 [Source:HGNC Symbol;Acc:HGNC:26421]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000019102	0	0	0	0	0	0	0	0	0	0	0	0	VSIG2	V-set and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17149]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006629//lipid metabolic process	--
ENSG00000019144	16.359	17.508	17.232	17.814	17.973	17.124	1736	1905	1343	1424	1634	1347	PHLDB1	pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0045180//basal cortex	GO:0005515//protein binding	GO:0010470//regulation of gastrulation;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0070507//regulation of microtubule cytoskeleton organization;GO:1904261//positive regulation of basement membrane assembly involved in embryonic body morphogenesis	--
ENSG00000019169	0	0	0	0	0	0	0	0	0	0	0	0	MARCO	macrophage receptor with collagenous structure [Source:HGNC Symbol;Acc:HGNC:6895]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K13884	GO:0005581//collagen trimer;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane	GO:0001540//amyloid-beta binding;GO:0001664//G protein-coupled receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0005044//scavenger receptor activity;GO:0038024//cargo receptor activity;GO:0038187//pattern recognition receptor activity	"GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006911//phagocytosis, engulfment;GO:0007166//cell surface receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0043277//apoptotic cell clearance;GO:0045087//innate immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0097242//amyloid-beta clearance"	--
ENSG00000019186	1.794	1.658	2.35	3.157	3.482	3.82	122	102	118	159	200	189	CYP24A1	cytochrome P450 family 24 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2602]	Metabolism;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cancer: overview;Endocrine system;Lipid metabolism	"ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko04928//Parathyroid hormone synthesis, secretion and action;ko00100//Steroid biosynthesis"	K07436;K07436;K07436;K07436	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008403//25-hydroxycholecalciferol-24-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0030342//1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity;GO:0046872//metal ion binding;GO:0062180//25-hydroxycholecalciferol-23-hydroxylase activity;GO:0062181//1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0070643//vitamin D 25-hydroxylase activity"	GO:0001649//osteoblast differentiation;GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0010430//fatty acid omega-oxidation;GO:0033280//response to vitamin D;GO:0042359//vitamin D metabolic process;GO:0042369//vitamin D catabolic process;GO:0070561//vitamin D receptor signaling pathway	--
ENSG00000019485	8.812	8.819	7.99	8.637	8.558	9.081	1383	1355	994	1047	1127	1020	PRDM11	PR/SET domain 11 [Source:HGNC Symbol;Acc:HGNC:13996]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	"GO:0010468//regulation of gene expression;GO:0030308//negative regulation of cell growth;GO:0032259//methylation;GO:0043408//regulation of MAPK cascade;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:2000271//positive regulation of fibroblast apoptotic process"	Others
ENSG00000019505	6.217	5.442	4.234	2.974	3.887	2.951	666	586	335	236	327	230	SYT13	synaptotagmin 13 [Source:HGNC Symbol;Acc:HGNC:14962]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0070382//exocytic vesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding	GO:0006906//vesicle fusion;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0071277//cellular response to calcium ion	--
ENSG00000019549	0.595	0.716	0.2	0.166	0.209	0.153	24	22	6	3	8	3	SNAI2	snail family transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:11094]	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04390//Hippo signaling pathway;ko04520//Adherens junction	K05706;K05706	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0003180//aortic valve morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003273//cell migration involved in endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006929//substrate-dependent cell migration;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007219//Notch signaling pathway;GO:0007605//sensory perception of sound;GO:0009314//response to radiation;GO:0010839//negative regulation of keratinocyte proliferation;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0014032//neural crest cell development;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032642//regulation of chemokine production;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0035066//positive regulation of histone acetylation;GO:0035921//desmosome disassembly;GO:0043066//negative regulation of apoptotic process;GO:0043473//pigmentation;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045600//positive regulation of fat cell differentiation;GO:0045667//regulation of osteoblast differentiation;GO:0050872//white fat cell differentiation;GO:0060021//roof of mouth development;GO:0060429//epithelium development;GO:0060536//cartilage morphogenesis;GO:0060693//regulation of branching involved in salivary gland morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0070563//negative regulation of vitamin D receptor signaling pathway;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071479//cellular response to ionizing radiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:2000647//negative regulation of stem cell proliferation;GO:2000810//regulation of bicellular tight junction assembly;GO:2000811//negative regulation of anoikis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	zf-C2H2
ENSG00000019582	23.793	24.557	28.481	22.544	26.248	25.114	687	717	605	479	629	531	CD74	CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05168//Herpes simplex virus 1 infection;ko05152//Tuberculosis;ko04612//Antigen processing and presentation	K06505;K06505;K06505	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005773//vacuole;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0032991//protein-containing complex;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0035693//NOS2-CD74 complex;GO:0042613//MHC class II protein complex;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0001540//amyloid-beta binding;GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0023026//MHC class II protein complex binding;GO:0035718//macrophage migration inhibitory factor binding;GO:0042289//MHC class II protein binding;GO:0042609//CD4 receptor binding;GO:0042658//MHC class II protein binding, via antigen binding groove;GO:0042802//identical protein binding;GO:0044183//protein folding chaperone;GO:0050998//nitric-oxide synthase binding"	"GO:0001516//prostaglandin biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002376//immune system process;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0002792//negative regulation of peptide secretion;GO:0002830//positive regulation of type 2 immune response;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0006886//intracellular protein transport;GO:0006952//defense response;GO:0006955//immune response;GO:0008283//cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016064//immunoglobulin mediated immune response;GO:0019882//antigen processing and presentation;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030336//negative regulation of cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0033674//positive regulation of kinase activity;GO:0034341//response to interferon-gamma;GO:0035691//macrophage migration inhibitory factor signaling pathway;GO:0043030//regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045058//T cell selection;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0045581//negative regulation of T cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046598//positive regulation of viral entry into host cell;GO:0048146//positive regulation of fibroblast proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050821//protein stabilization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0060907//positive regulation of macrophage cytokine production;GO:0065003//protein-containing complex assembly;GO:0070206//protein trimerization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:2000448//positive regulation of macrophage migration inhibitory factor signaling pathway"	--
ENSG00000019991	0	0.127	0.046	0	0.056	0	0	2	1	0	2	0	HGF	hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Infectious disease: parasitic	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05225//Hepatocellular carcinoma;ko05226//Gastric cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05144//Malaria	K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460;K05460	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen	GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0000278//mitotic cell cycle;GO:0000902//cell morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001889//liver development;GO:0001934//positive regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0010507//negative regulation of autophagy;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030335//positive regulation of cell migration;GO:0031100//animal organ regeneration;GO:0031643//positive regulation of myelination;GO:0032715//negative regulation of interleukin-6 production;GO:0032733//positive regulation of interleukin-10 production;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045669//positive regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0050673//epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0051450//myoblast proliferation;GO:0060326//cell chemotaxis;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0070572//positive regulation of neuron projection regeneration;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:1900744//regulation of p38MAPK cascade;GO:1901299//negative regulation of hydrogen peroxide-mediated programmed cell death;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902947//regulation of tau-protein kinase activity;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000019995	9.17	8.936	8.936	7.461	8.397	9.18	1083.2	1061.03	779.61	652.8	838.05	789.05	ZRANB1	zinc finger RANBP2-type containing 1 [Source:HGNC Symbol;Acc:HGNC:18224]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0101005//deubiquitinase activity	GO:0006508//proteolysis;GO:0007010//cytoskeleton organization;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035523//protein K29-linked deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1990168//protein K33-linked deubiquitination	--
ENSG00000020129	12.171	14.891	13.138	19.471	16.332	19.793	839	969	688	795	867	861	NCDN	neurochondrin [Source:HGNC Symbol;Acc:HGNC:17597]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse;GO:0098794//postsynapse	GO:0005515//protein binding	GO:0031175//neuron projection development;GO:0045453//bone resorption;GO:0048168//regulation of neuronal synaptic plasticity	--
ENSG00000020181	21.32	23.782	19.592	12.326	15.109	13.794	3068.87	3436.65	2084.17	1312.74	1837.25	1445.55	ADGRA2	adhesion G protein-coupled receptor A2 [Source:HGNC Symbol;Acc:HGNC:17849]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030175//filopodium;GO:0042995//cell projection;GO:1990909//Wnt signalosome	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0002040//sprouting angiogenesis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007417//central nervous system development;GO:0010595//positive regulation of endothelial cell migration;GO:0016055//Wnt signaling pathway;GO:0043542//endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0050920//regulation of chemotaxis;GO:0090210//regulation of establishment of blood-brain barrier;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway	--
ENSG00000020256	6.208	5.549	6.185	6.985	6.836	7.379	382	336	276	320	354	331	ZFP64	ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043076//megasporocyte nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048762//mesenchymal cell differentiation	zf-C2H2
ENSG00000020426	13.795	11.921	11.405	10.114	8.844	11.517	337	300	224	180	177	191	MNAT1	MNAT1 component of CDK activating kinase [Source:HGNC Symbol;Acc:HGNC:7181]	Genetic Information Processing;Genetic Information Processing	Transcription;Replication and repair	ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K10842;K10842	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005675//transcription factor TFIIH holo complex;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0070516//CAK-ERCC2 complex;GO:0070985//transcription factor TFIIK complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007512//adult heart development;GO:0021591//ventricular system development;GO:0043066//negative regulation of apoptotic process;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051592//response to calcium ion;GO:0065003//protein-containing complex assembly;GO:1905775//negative regulation of DNA helicase activity;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000020577	1.93	1.881	1.391	0.972	0.811	0.7	236	248	143	100	85	73	SAMD4A	sterile alpha motif domain containing 4A [Source:HGNC Symbol;Acc:HGNC:23023]	-	-	-	-	GO:0000932//P-body;GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0030371//translation repressor activity	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation	--
ENSG00000020633	0	0	0	0	0	0	0	0	0	0	0	0	RUNX3	RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05169//Epstein-Barr virus infection;ko04658//Th1 and Th2 cell differentiation	K09279;K09279	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016513//core-binding factor complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0002062//chondrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0030097//hemopoiesis;GO:0030182//neuron differentiation;GO:0043371//negative regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048935//peripheral nervous system neuron development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0071559//response to transforming growth factor beta"	Runt
ENSG00000020922	6.277	4.015	3.27	2.807	3.376	3.35	454	356	238	212	247	212	MRE11	"MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230]"	Cellular Processes;Genetic Information Processing;Genetic Information Processing	Cell growth and death;Replication and repair;Replication and repair	ko04218//Cellular senescence;ko03440//Homologous recombination;ko03450//Non-homologous end-joining	K10865;K10865;K10865	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0030870//Mre11 complex;GO:0035861//site of double-strand break;GO:0070533//BRCA1-C complex;GO:0098687//chromosomal region"	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003690//double-stranded DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	GO:0000019//regulation of mitotic recombination;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0000729//DNA double-strand break processing;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007004//telomere maintenance via telomerase;GO:0007062//sister chromatid cohesion;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0008283//cell population proliferation;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0031860//telomeric 3' overhang formation;GO:0031954//positive regulation of protein autophosphorylation;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0033674//positive regulation of kinase activity;GO:0035825//homologous recombination;GO:0042138//meiotic DNA double-strand break formation;GO:0043066//negative regulation of apoptotic process;GO:0044818//mitotic G2/M transition checkpoint;GO:0051276//chromosome organization;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0097552//mitochondrial double-strand break repair via homologous recombination;GO:0110025//DNA strand resection involved in replication fork processing	--
ENSG00000021300	215.87	211.998	249.965	240.342	227.724	226.173	8317	8471	7081	7058	7407	6621	PLEKHB1	pleckstrin homology domain containing B1 [Source:HGNC Symbol;Acc:HGNC:19079]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007602//phototransduction;GO:0045595//regulation of cell differentiation	--
ENSG00000021355	4.732	5.153	5.51	5.336	3.826	5.62	243	266	209	203	166	210	SERPINB1	serpin family B member 1 [Source:HGNC Symbol;Acc:HGNC:3311]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0044194//cytolytic granule;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0044342//type B pancreatic cell proliferation	--
ENSG00000021461	0	0	0	0	0	0	0	0	0	0	0	0	CYP3A43	cytochrome P450 family 3 subfamily A member 43 [Source:HGNC Symbol;Acc:HGNC:17450]	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K17692	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity"	GO:0008202//steroid metabolic process;GO:0070989//oxidative demethylation	--
ENSG00000021488	0.157	0.156	0	0	0.036	0.127	4	4	0	0	1	3	SLC7A9	solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K13868	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042605//peptide antigen binding	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport;GO:0015811//L-cystine transport;GO:0055085//transmembrane transport;GO:0065003//protein-containing complex assembly;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000021574	7.235	4.642	5.929	2.716	4.477	4.266	444	329	268	169	230	233	SPAST	spastin [Source:HGNC Symbol;Acc:HGNC:11233]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071782//endoplasmic reticulum tubular network;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008568//microtubule-severing ATPase activity;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity;GO:0043014//alpha-tubulin binding;GO:0044877//protein-containing complex binding;GO:0048487//beta-tubulin binding	GO:0000281//mitotic cytokinesis;GO:0001578//microtubule bundle formation;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007049//cell cycle;GO:0007084//mitotic nuclear membrane reassembly;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0008089//anterograde axonal transport;GO:0008152//metabolic process;GO:0010458//exit from mitosis;GO:0019896//axonal transport of mitochondrion;GO:0030154//cell differentiation;GO:0031117//positive regulation of microtubule depolymerization;GO:0031468//nuclear membrane reassembly;GO:0032467//positive regulation of cytokinesis;GO:0032506//cytokinetic process;GO:0034214//protein hexamerization;GO:0051013//microtubule severing;GO:0051228//mitotic spindle disassembly;GO:0051260//protein homooligomerization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis;GO:0090148//membrane fission	--
ENSG00000021645	0.486	0.456	0.265	0.675	0.64	0.898	38	35	15	40	41	52	NRXN3	neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07377	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0098793//presynapse;GO:0098982//GABA-ergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0097109//neuroligin family protein binding	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007612//learning;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0071625//vocalization behavior;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000021762	4.543	3.718	3.67	4.361	4.727	3.402	266	261	174	197	242	170	OSBPL5	oxysterol binding protein like 5 [Source:HGNC Symbol;Acc:HGNC:16392]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K20464	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0001786//phosphatidylserine binding;GO:0005548//phospholipid transporter activity;GO:0008142//oxysterol binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0140343//phosphatidylserine transfer activity	GO:0006869//lipid transport;GO:0006893//Golgi to plasma membrane transport;GO:0008203//cholesterol metabolic process;GO:0015914//phospholipid transport;GO:0030301//cholesterol transport;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0120009//intermembrane lipid transfer	--
ENSG00000021776	9.384	8.321	8.22	6.512	7.378	8.43	1522	1339	944	765	1019	963	AQR	aquarius intron-binding spliceosomal factor [Source:HGNC Symbol;Acc:HGNC:29513]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12874	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0034458//3'-5' RNA helicase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000021826	1.888	1.961	1.315	1.404	1.935	1.926	210	220	115	121	186	161	CPS1	carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Energy metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis;ko00910//Nitrogen metabolism"	K01948;K01948;K01948;K01948;K01948;K01948	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0032991//protein-containing complex;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004087//carbamoyl-phosphate synthase (ammonia) activity;GO:0004088//carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0004175//endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0016595//glutamate binding;GO:0016874//ligase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0072341//modified amino acid binding	GO:0000050//urea cycle;GO:0001889//liver development;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006508//proteolysis;GO:0006541//glutamine metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0007494//midgut development;GO:0008152//metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010043//response to zinc ion;GO:0014075//response to amine;GO:0019240//citrulline biosynthetic process;GO:0019433//triglyceride catabolic process;GO:0032094//response to food;GO:0032496//response to lipopolysaccharide;GO:0033762//response to glucagon;GO:0034201//response to oleic acid;GO:0034641//cellular nitrogen compound metabolic process;GO:0042311//vasodilation;GO:0042594//response to starvation;GO:0043200//response to amino acid;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0046209//nitric oxide metabolic process;GO:0048545//response to steroid hormone;GO:0050667//homocysteine metabolic process;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0055081//anion homeostasis;GO:0060416//response to growth hormone;GO:0070365//hepatocyte differentiation;GO:0070409//carbamoyl phosphate biosynthetic process;GO:0071242//cellular response to ammonium ion;GO:0071320//cellular response to cAMP;GO:0071377//cellular response to glucagon stimulus;GO:0071400//cellular response to oleic acid;GO:0071548//response to dexamethasone	--
ENSG00000021852	0	0	0	0	0	0	0	0	0	0	0	0	C8B	complement C8 beta chain [Source:HGNC Symbol;Acc:HGNC:1353]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: parasitic;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05146//Amoebiasis;ko04610//Complement and coagulation cascades	K03998;K03998;K03998;K03998;K03998	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	"GO:0002376//immune system process;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response"	--
ENSG00000022267	34.647	42.679	27.893	26.64	29.418	28.778	1722	1984	1038	927	1106	1032	FHL1	four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702]	Environmental Information Processing	Signal transduction	ko04630//JAK-STAT signaling pathway	K14365	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0003254//regulation of membrane depolarization;GO:0007517//muscle organ development;GO:0009887//animal organ morphogenesis;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0043268//positive regulation of potassium ion transport;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000022277	45.759	44.106	47.59	43.114	42.188	41.041	1476	1523	1097	1105	1243	1028	RTF2	replication termination factor 2 [Source:HGNC Symbol;Acc:HGNC:15890]	-	-	-	-	GO:0005634//nucleus;GO:0005657//replication fork;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0072711//cellular response to hydroxyurea;GO:0097752//regulation of DNA stability;GO:1902979//mitotic DNA replication termination	--
ENSG00000022355	0.365	0.159	0.337	0.242	0.575	0.254	14	14	18	12	30	13	GABRA1	gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:1902710//GABA receptor complex;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0016917//GABA receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport;GO:1904862//inhibitory synapse assembly"	--
ENSG00000022556	0	0	0	0	0.05	0	0	0	0	0	3	0	NLRP2	NLR family pyrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:22948]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0032090//Pyrin domain binding	GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032731//positive regulation of interleukin-1 beta production;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response	--
ENSG00000022567	17.703	18.178	20.875	20.99	23.762	21.579	2690	2821	2382	2358	3031	2423	SLC45A4	solute carrier family 45 member 4 [Source:HGNC Symbol;Acc:HGNC:29196]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008506//sucrose:proton symporter activity	GO:0015770//sucrose transport	--
ENSG00000022840	46.529	45.54	50.158	48.26	46.858	48.604	3157	3172.61	2470	2389	2792	2284	RNF10	ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0098978//glutamatergic synapse;GO:0099147//extrinsic component of postsynaptic density membrane	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0010626//negative regulation of Schwann cell proliferation;GO:0031643//positive regulation of myelination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051865//protein autoubiquitination;GO:0099527//postsynapse to nucleus signaling pathway"	--
ENSG00000022976	2.486	3.359	3.408	4.509	4.099	3.268	152.98	162.25	145.84	152.35	169.03	141.72	ZNF839	zinc finger protein 839 [Source:HGNC Symbol;Acc:HGNC:20345]	-	-	-	-	-	GO:0046872//metal ion binding	-	--
ENSG00000023041	18.71	19.633	19.774	17.848	21.99	22.818	876	915.05	692	618.05	873.04	781	ZDHHC6	zinc finger DHHC-type palmitoyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:19160]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0010636//positive regulation of mitochondrial fusion;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0140438//protein stearoylation	--
ENSG00000023171	9.539	8.527	9.178	9.381	8.569	9.515	1436	1299	1132	1025	1187	1041	GRAMD1B	GRAM domain containing 1B [Source:HGNC Symbol;Acc:HGNC:29214]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044232//organelle membrane contact site;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0001786//phosphatidylserine binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0070300//phosphatidic acid binding;GO:0120015//sterol transfer activity;GO:0120020//cholesterol transfer activity	GO:0006869//lipid transport;GO:0015918//sterol transport;GO:0032366//intracellular sterol transport;GO:0042632//cholesterol homeostasis;GO:0071397//cellular response to cholesterol;GO:0120009//intermembrane lipid transfer	--
ENSG00000023191	102.228	109.506	114.557	141.883	131.077	156.261	3495	3737	2808	3703	3768	3735	RNH1	ribonuclease/angiogenin inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:10074]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032311//angiogenin-PRI complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008428//ribonuclease inhibitor activity	GO:0006402//mRNA catabolic process;GO:0043086//negative regulation of catalytic activity;GO:0045765//regulation of angiogenesis	--
ENSG00000023228	32.775	30.755	34.721	30.938	33.57	32.916	2466	2088	1642	1399	1777	1651	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934;K03934	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070469//respirasome	"GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0008637//apoptotic mitochondrial changes;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042773//ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0045333//cellular respiration;GO:0046034//ATP metabolic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0072593//reactive oxygen species metabolic process"	--
ENSG00000023287	8.11	5.7	3.75	3.128	4.494	5.174	932	596	381	268	436	410	RB1CC1	RB1 inducible coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:15574]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Aging	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04211//Longevity regulating pathway	K17589;K17589;K17589;K17589;K17589;K17589;K17589	GO:0000407//phagophore assembly site;GO:0000421//autophagosome membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane;GO:0031965//nuclear membrane;GO:0034045//phagophore assembly site membrane;GO:1990316//Atg1/ULK1 kinase complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0060090//molecular adaptor activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0001889//liver development;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0006996//organelle organization;GO:0007049//cell cycle;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0030242//autophagy of peroxisome;GO:0034727//piecemeal microautophagy of the nucleus;GO:0043066//negative regulation of apoptotic process;GO:0045793//positive regulation of cell size;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0061709//reticulophagy;GO:0061723//glycophagy;GO:1903059//regulation of protein lipidation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000023318	21.001	18.251	17.78	19.105	20.029	21.989	1719	1484	1136	1138	1373	1322	ERP44	endoplasmic reticulum protein 44 [Source:HGNC Symbol;Acc:HGNC:18311]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0009986//cell surface;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0009100//glycoprotein metabolic process;GO:0034976//response to endoplasmic reticulum stress;GO:0045454//cell redox homeostasis	--
ENSG00000023330	29.919	32.837	30.656	29.47	33.272	28.557	1304	1418	981	997	1276	955	ALAS1	5'-aminolevulinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:396]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Amino acid metabolism	"ko01100//Metabolic pathways;ko00860//Porphyrin metabolism;ko00260//Glycine, serine and threonine metabolism"	K00643;K00643;K00643	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0003870//5-aminolevulinate synthase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006778//porphyrin-containing compound metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0009058//biosynthetic process;GO:0033014//tetrapyrrole biosynthetic process;GO:0042541//hemoglobin biosynthetic process;GO:0048821//erythrocyte development	--
ENSG00000023445	0.882	0.36	0.713	0.442	0.374	0.388	64	42	38	25	29	34	BIRC3	baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	"Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Signal transduction;Cell growth and death;Signal transduction;Folding, sorting and degradation;Cell growth and death;Signal transduction;Infectious disease: parasitic;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05132//Salmonella infection;ko04510//Focal adhesion;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04390//Hippo signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko01524//Platinum drug resistance;ko04215//Apoptosis - multiple species	K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0045121//membrane raft	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0038061//NIK/NF-kappaB signaling;GO:0039535//regulation of RIG-I signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043067//regulation of programmed cell death;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045088//regulation of innate immune response;GO:0050727//regulation of inflammatory response;GO:0051726//regulation of cell cycle;GO:0052548//regulation of endopeptidase activity;GO:0060544//regulation of necroptotic process;GO:0060546//negative regulation of necroptotic process;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:2000116//regulation of cysteine-type endopeptidase activity	--
ENSG00000023516	8.14	4.692	4.905	3.486	4.063	5.226	1674	970	745	531	706	782	AKAP11	A-kinase anchoring protein 11 [Source:HGNC Symbol;Acc:HGNC:369]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0051018//protein kinase A binding	GO:0003091//renal water homeostasis;GO:0008104//protein localization;GO:0030866//cortical actin cytoskeleton organization;GO:0034613//cellular protein localization;GO:0035556//intracellular signal transduction;GO:0036010//protein localization to endosome	--
ENSG00000023572	4.512	2.785	4.951	4.693	3.667	5.682	220.8	114.16	98.92	98.51	103.27	139.64	GLRX2	glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle	"GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding;GO:0008794//arsenate reductase (glutaredoxin) activity;GO:0009055//electron transfer activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0097573//glutathione oxidoreductase activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006749//glutathione metabolic process;GO:0006915//apoptotic process;GO:0007568//aging;GO:0009266//response to temperature stimulus;GO:0009966//regulation of signal transduction;GO:0010033//response to organic substance;GO:0022900//electron transport chain;GO:0030154//cell differentiation;GO:0042262//DNA protection;GO:0042542//response to hydrogen peroxide;GO:0045454//cell redox homeostasis;GO:0051775//response to redox state;GO:0071451//cellular response to superoxide"	--
ENSG00000023608	3.124	2.479	2.215	1.581	1.893	2.836	168	134	88	63	86	111	SNAPC1	small nuclear RNA activating complex polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:11134]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0019185//snRNA-activating protein complex	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0043565//sequence-specific DNA binding	GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III	--
ENSG00000023697	7.475	8.31	7.096	7.677	8.287	10.376	229	273	171	180	185	236	DERA	deoxyribose-phosphate aldolase [Source:HGNC Symbol;Acc:HGNC:24269]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00030//Pentose phosphate pathway	K01619;K01619	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003824//catalytic activity;GO:0004139//deoxyribose-phosphate aldolase activity;GO:0005515//protein binding;GO:0016829//lyase activity	GO:0006098//pentose-phosphate shunt;GO:0009264//deoxyribonucleotide catabolic process;GO:0016052//carbohydrate catabolic process;GO:0046121//deoxyribonucleoside catabolic process;GO:0046386//deoxyribose phosphate catabolic process	--
ENSG00000023734	43.246	41.903	39.854	41.822	38.071	40.2	1673	1628	1137	1199	1234	1132	STRAP	serine/threonine kinase receptor associated protein [Source:HGNC Symbol;Acc:HGNC:30796]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:1990447//U2 snRNP binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0022618//ribonucleoprotein complex assembly;GO:0030182//neuron differentiation;GO:0030277//maintenance of gastrointestinal epithelium;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0048856//anatomical structure development"	--
ENSG00000023839	0.017	0.043	0.011	0.078	0.101	0.143	2	1	1	7	2	5	ABCC2	ATP binding cassette subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:53]	Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases	Digestive system;Drug resistance: antineoplastic;Membrane transport;Drug resistance: antineoplastic	ko04976//Bile secretion;ko01524//Platinum drug resistance;ko02010//ABC transporters;ko01523//Antifolate resistance	K05666;K05666;K05666;K05666	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0046581//intercellular canaliculus	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008514//organic anion transmembrane transporter activity;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015127//bilirubin transmembrane transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0022857//transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0010629//negative regulation of gene expression;GO:0015698//inorganic anion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0015723//bilirubin transport;GO:0042167//heme catabolic process;GO:0046618//xenobiotic export;GO:0055085//transmembrane transport;GO:0070633//transepithelial transport;GO:0071716//leukotriene transport;GO:0150104//transport across blood-brain barrier;GO:1990962//xenobiotic transport across blood-brain barrier	--
ENSG00000023892	0.336	0.397	0.142	0.624	0.323	0.462	16	19	5	22	13	16	DEF6	DEF6 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:2760]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030175//filopodium;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000023902	6.476	6.067	7.369	5.934	5.426	5.558	283	266	238	192	201	177	PLEKHO1	pleckstrin homology domain containing O1 [Source:HGNC Symbol;Acc:HGNC:24310]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0036195//muscle cell projection membrane	GO:0005515//protein binding	GO:0007520//myoblast fusion;GO:0008360//regulation of cell shape;GO:0051451//myoblast migration;GO:0072673//lamellipodium morphogenesis;GO:1901739//regulation of myoblast fusion	--
ENSG00000023909	4.855	3.521	4.039	3.367	3.525	4.475	425	309	249	228	290	284	GCLM	glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312]	Metabolism;Metabolism;Metabolism;Cellular Processes	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism;Cell growth and death	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00270//Cysteine and methionine metabolism;ko04216//Ferroptosis	K11205;K11205;K11205;K11205	GO:0005829//cytosol;GO:0017109//glutamate-cysteine ligase complex	GO:0004357//glutamate-cysteine ligase activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0035226//glutamate-cysteine ligase catalytic subunit binding;GO:0044877//protein-containing complex binding	GO:0006534//cysteine metabolic process;GO:0006536//glutamate metabolic process;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0007584//response to nutrient;GO:0008637//apoptotic mitochondrial changes;GO:0009410//response to xenobiotic stimulus;GO:0014823//response to activity;GO:0035229//positive regulation of glutamate-cysteine ligase activity;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0035733//hepatic stellate cell activation;GO:0043524//negative regulation of neuron apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0044752//response to human chorionic gonadotropin;GO:0051409//response to nitrosative stress;GO:0051900//regulation of mitochondrial depolarization;GO:0071333//cellular response to glucose stimulus;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0097069//cellular response to thyroxine stimulus;GO:0097746//blood vessel diameter maintenance;GO:1990830//cellular response to leukemia inhibitory factor;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000024048	6.171	5.458	5.112	4.083	4.809	5.584	1010	898	618	495	665	665	UBR2	ubiquitin protein ligase E3 component n-recognin 2 [Source:HGNC Symbol;Acc:HGNC:21289]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0070728//leucine binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0031507//heterochromatin assembly;GO:0032007//negative regulation of TOR signaling;GO:0033522//histone H2A ubiquitination;GO:0071233//cellular response to leucine;GO:0071596//ubiquitin-dependent protein catabolic process via the N-end rule pathway	--
ENSG00000024422	25.687	27.843	27.686	25.337	25.571	21.469	1868	2014	1487	1353	1556	1136	EHD2	EH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3243]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12469	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0010008//endosome membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030139//endocytic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0016197//endosomal transport;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0032456//endocytic recycling;GO:0060271//cilium assembly;GO:0072659//protein localization to plasma membrane;GO:0097320//plasma membrane tubulation;GO:1901741//positive regulation of myoblast fusion;GO:2001137//positive regulation of endocytic recycling	--
ENSG00000024526	0.776	0.759	1.053	0.27	0.367	0.51	79	55	38	19	32	33	DEPDC1	DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949]	-	-	-	-	GO:0005634//nucleus;GO:0017053//transcription repressor complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity"	--
ENSG00000024862	9.975	10.462	10.312	9.552	8.42	8.767	258	272	197	183	184	165	CCDC28A	coiled-coil domain containing 28A [Source:HGNC Symbol;Acc:HGNC:21098]	-	-	-	-	-	-	-	--
ENSG00000025039	23.197	23.802	21.417	23.374	24.284	23.567	2365	2443	1611	1768	2095	1751	RRAGD	Ras related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: bacterial;Signal transduction;Transport and catabolism	ko05131//Shigellosis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K16186;K16186;K16186	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:1990131//Gtr1-Gtr2 GTPase complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0046982//protein heterodimerization activity;GO:0051020//GTPase binding	GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0032008//positive regulation of TOR signaling;GO:0034613//cellular protein localization;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:1904263//positive regulation of TORC1 signaling;GO:1990253//cellular response to leucine starvation	--
ENSG00000025156	7.51	6.558	7.306	5.65	7.153	7.125	409	360	294	210	263	280	HSF2	heat shock transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:5225]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II"	HSF
ENSG00000025293	5.412	6.817	4.941	4.273	4.271	4.227	660	677	445	386	411	375	PHF20	PHD finger protein 20 [Source:HGNC Symbol;Acc:HGNC:16098]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0044545//NSL complex;GO:0071339//MLL1 complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000025423	0.319	0.317	0.518	0.258	0.443	0.657	10	10	12	6	12	15	HSD17B6	hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Lipid metabolism	ko01100//Metabolic pathways;ko00830//Retinol metabolism;ko00140//Steroid hormone biosynthesis	K13369;K13369;K13369	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0003824//catalytic activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047023//androsterone dehydrogenase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0006629//lipid metabolic process;GO:0006702//androgen biosynthetic process;GO:0006710//androgen catabolic process;GO:0008202//steroid metabolic process;GO:0022900//electron transport chain;GO:0062175//brexanolone catabolic process	--
ENSG00000025434	7.209	8.113	7.955	8.033	9.142	11.18	208	220	190	175	218	202	NR1H3	nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Endocrine and metabolic disease;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system	ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko04931//Insulin resistance;ko03320//PPAR signaling pathway	K08536;K08536;K08536;K08536	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043235//receptor complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015485//cholesterol binding;GO:0032810//sterol response element binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0009755//hormone-mediated signaling pathway;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032369//negative regulation of lipid transport;GO:0032376//positive regulation of cholesterol transport;GO:0032411//positive regulation of transporter activity;GO:0032570//response to progesterone;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042632//cholesterol homeostasis;GO:0042752//regulation of circadian rhythm;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043031//negative regulation of macrophage activation;GO:0043277//apoptotic cell clearance;GO:0044255//cellular lipid metabolic process;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045861//negative regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048550//negative regulation of pinocytosis;GO:0050728//negative regulation of inflammatory response;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0055088//lipid homeostasis;GO:0055092//sterol homeostasis;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0070328//triglyceride homeostasis;GO:0071222//cellular response to lipopolysaccharide;GO:0090188//negative regulation of pancreatic juice secretion;GO:0090341//negative regulation of secretion of lysosomal enzymes;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1903573//negative regulation of response to endoplasmic reticulum stress"	THR-like
ENSG00000025708	0.282	0.67	0.188	0.495	0.777	1.226	9	24	4	13	19	21	TYMP	thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]	Metabolism;Metabolism;Metabolism;Human Diseases	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism;Cancer: specific types	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism;ko05219//Bladder cancer	K00758;K00758;K00758;K00758	GO:0005829//cytosol	"GO:0004645//1,4-alpha-oligoglucan phosphorylase activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0009032//thymidine phosphorylase activity;GO:0016154//pyrimidine-nucleoside phosphorylase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042803//protein homodimerization activity"	GO:0000002//mitochondrial genome maintenance;GO:0001525//angiogenesis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0031641//regulation of myelination;GO:0046074//dTMP catabolic process;GO:0051969//regulation of transmission of nerve impulse;GO:1905333//regulation of gastric motility	--
ENSG00000025770	13.107	14.305	12.442	14.209	14.374	11.874	588.62	629.74	462.45	532.75	527.81	422.48	NCAPH2	non-SMC condensin II complex subunit H2 [Source:HGNC Symbol;Acc:HGNC:25071]	-	-	-	-	GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0030054//cell junction;GO:0045171//intercellular bridge	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007076//mitotic chromosome condensation;GO:0007143//female meiotic nuclear division;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0033077//T cell differentiation in thymus;GO:0051306//mitotic sister chromatid separation;GO:0051309//female meiosis chromosome separation;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000025772	24.509	24.943	23.094	23.587	24.642	20.923	1003	1026	698	715	852	623	TOMM34	translocase of outer mitochondrial membrane 34 [Source:HGNC Symbol;Acc:HGNC:15746]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0031072//heat shock protein binding	GO:0006626//protein targeting to mitochondrion	--
ENSG00000025796	32.904	27.675	25.837	17.618	18.744	20.581	4366	3640	2545	1581	2112	1975	SEC63	"SEC63 homolog, protein translocation regulator [Source:HGNC Symbol;Acc:HGNC:21082]"	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko03060//Protein export	K09540;K09540	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031207//Sec62/Sec63 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0038023//signaling receptor activity	"GO:0001889//liver development;GO:0006612//protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0006807//nitrogen compound metabolic process;GO:0010259//multicellular organism aging;GO:0015031//protein transport;GO:0031204//posttranslational protein targeting to membrane, translocation"	--
ENSG00000025800	11.065	10.617	12.026	9.078	10.094	11.728	1688	1624	1355	1019	1301	1298	KPNA6	karyopherin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6399]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Infectious disease: viral;Translation	ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K15042;K15042;K15042	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0042564//NLS-dependent protein nuclear import complex;GO:0043657//host cell	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0015031//protein transport;GO:0016032//viral process;GO:0019079//viral genome replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060135//maternal process involved in female pregnancy;GO:0075506//entry of viral genome into host nucleus through nuclear pore complex via importin;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1903902//positive regulation of viral life cycle	--
ENSG00000026025	1256.759	1306.724	1102.045	1428.883	1378.433	1101.606	48702	50825	31504	40972	45134	31067	VIM	vimentin [Source:HGNC Symbol;Acc:HGNC:12692]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05169//Epstein-Barr virus infection;ko05206//MicroRNAs in cancer	K07606;K07606	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005844//polysome;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045111//intermediate filament cytoskeleton;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003725//double-stranded RNA binding;GO:0005200//structural constituent of cytoskeleton;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0097110//scaffold protein binding;GO:1990254//keratin filament binding	GO:0010628//positive regulation of gene expression;GO:0010977//negative regulation of neuron projection development;GO:0014002//astrocyte development;GO:0032967//positive regulation of collagen biosynthetic process;GO:0043488//regulation of mRNA stability;GO:0045103//intermediate filament-based process;GO:0045109//intermediate filament organization;GO:0045727//positive regulation of translation;GO:0060020//Bergmann glial cell differentiation;GO:0060395//SMAD protein signal transduction;GO:0070307//lens fiber cell development;GO:0071222//cellular response to lipopolysaccharide;GO:0071225//cellular response to muramyl dipeptide;GO:0071346//cellular response to interferon-gamma	--
ENSG00000026036	0.074	0	0.377	0	0.053	0	7.38	0	27.83	0	4.5	0	RTEL1-TNFRSF6B	RTEL1-TNFRSF6B readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44095]	-	-	-	-	GO:0005634//nucleus	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0000723//telomere maintenance;GO:0006139//nucleobase-containing compound metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0032508//DNA duplex unwinding	--
ENSG00000026103	0.285	0.207	0.294	0.487	0.452	0.789	12	8	9	17	15	21	FAS	Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Immune disease;Signal transduction;Immune disease;Infectious disease: parasitic;Infectious disease: parasitic;Drug resistance: antineoplastic;Cell growth and death;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05320//Autoimmune thyroid disease;ko04668//TNF signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko05143//African trypanosomiasis;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390;K04390	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0031264//death-inducing signaling complex;GO:0031265//CD95 death-inducing signaling complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019900//kinase binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0006955//immune response;GO:0007165//signal transduction;GO:0032872//regulation of stress-activated MAPK cascade;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034198//cellular response to amino acid starvation;GO:0036337//Fas signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0065003//protein-containing complex assembly;GO:0071260//cellular response to mechanical stimulus;GO:0071455//cellular response to hyperoxia;GO:0097049//motor neuron apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097527//necroptotic signaling pathway;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000026297	12.793	13.899	15.612	17.71	18.573	15.35	302	308	273	309	364	262	RNASET2	ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0033897//ribonuclease T2 activity	"GO:0002376//immune system process;GO:0006401//RNA catabolic process;GO:0016070//RNA metabolic process;GO:0045087//innate immune response;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000026508	47.265	50.693	32.365	12.54	17.621	21.307	2985	2981	1604	547	828	786	CD44	CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Immune system;Signaling molecules and interaction	ko05169//Epstein-Barr virus infection;ko05131//Shigellosis;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko04640//Hematopoietic cell lineage;ko04512//ECM-receptor interaction	K06256;K06256;K06256;K06256;K06256;K06256	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030667//secretory granule membrane;GO:0031258//lamellipodium membrane;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005540//hyaluronic acid binding	"GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0016477//cell migration;GO:0019221//cytokine-mediated signaling pathway;GO:0030214//hyaluronan catabolic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042110//T cell activation;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0044319//wound healing, spreading of cells;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051216//cartilage development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070487//monocyte aggregation;GO:0098609//cell-cell adhesion;GO:1900625//positive regulation of monocyte aggregation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000392//regulation of lamellipodium morphogenesis"	--
ENSG00000026559	2.96	2.162	2.437	2.84	2.459	2.681	85	70	53	69	64	59	KCNG1	potassium voltage-gated channel modifier subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:6248]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1902259//regulation of delayed rectifier potassium channel activity	--
ENSG00000026652	4.193	4.229	3.518	3.816	4.479	5.257	653	644	427	417	452	499	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:20885]	Metabolism;Environmental Information Processing;Metabolism;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13523;K13523;K13523;K13523	GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042171//lysophosphatidic acid acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process	--
ENSG00000026751	0.354	0.437	0.105	0.155	0.28	0.028	19	18	4	6	8	1	SLAMF7	SLAM family member 7 [Source:HGNC Symbol;Acc:HGNC:21394]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0030101//natural killer cell activation;GO:0042110//T cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0045087//innate immune response	--
ENSG00000026950	4.259	4.265	4.469	4.06	4.337	4.438	266	283.29	210	191.45	218	197	BTN3A1	butyrophilin subfamily 3 member A1 [Source:HGNC Symbol;Acc:HGNC:1138]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0032729//positive regulation of interferon-gamma production;GO:0050798//activated T cell proliferation;GO:0050852//T cell receptor signaling pathway	--
ENSG00000027001	8.018	9.226	9.184	10.278	8.46	9.434	396	458	335	376	353	339	MIPEP	mitochondrial intermediate peptidase [Source:HGNC Symbol;Acc:HGNC:7104]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0006627//protein processing involved in protein targeting to mitochondrion	--
ENSG00000027075	1.078	1.09	1.209	1.3	1.461	1.156	61	72	56	60	84	59.32	PRKCH	protein kinase C eta [Source:HGNC Symbol;Acc:HGNC:9403]	Organismal Systems;Organismal Systems	Circulatory system;Sensory system	ko04270//Vascular smooth muscle contraction;ko04750//Inflammatory mediator regulation of TRP channels	K18051;K18051	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0034351//negative regulation of glial cell apoptotic process;GO:0035556//intracellular signal transduction;GO:0045618//positive regulation of keratinocyte differentiation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060252//positive regulation of glial cell proliferation;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000027644	0.009	0.018	0.038	0.188	0.099	0.013	1	2	3	15	9	1	INSRR	insulin receptor related receptor [Source:HGNC Symbol;Acc:HGNC:6093]	Cellular Processes;Human Diseases	Cell motility;Cancer: specific types	ko04810//Regulation of actin cytoskeleton;ko05215//Prostate cancer	K05086;K05086	GO:0005887//integral component of plasma membrane;GO:0005899//insulin receptor complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005009//insulin-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043560//insulin receptor substrate binding	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030238//male sex determination;GO:0031532//actin cytoskeleton reorganization;GO:0033674//positive regulation of kinase activity;GO:0046777//protein autophosphorylation;GO:0071469//cellular response to alkaline pH	--
ENSG00000027697	21.598	19.726	19.64	16.212	17.79	19.436	889	816	607	516	626	603	IFNGR1	interferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: parasitic;Development and regeneration;Signal transduction;Immune system;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko04066//HIF-1 signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321//Inflammatory bowel disease	K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132;K05132	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004906//interferon-gamma receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0001774//microglial cell activation;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0048143//astrocyte activation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0098586//cellular response to virus;GO:1900222//negative regulation of amyloid-beta clearance;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000027847	20.402	22.003	19.306	19.334	20.935	17.625	688	716	488	494	609	447	B4GALT7	"beta-1,4-galactosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:930]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00733;K00733;K00733	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment;GO:0032580//Golgi cisterna membrane;GO:0098588//bounding membrane of organelle	"GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0005515//protein binding;GO:0008378//galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0046525//xylosylprotein 4-beta-galactosyltransferase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006029//proteoglycan metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0030166//proteoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0070085//glycosylation;GO:0097435//supramolecular fiber organization;GO:1901137//carbohydrate derivative biosynthetic process	--
ENSG00000027869	0.06	0.03	0.122	0.122	0.107	0	2	1	3	3	3	0	SH2D2A	SH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821]	Environmental Information Processing	Signal transduction	ko04370//VEGF signaling pathway	K08273	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0030154//cell differentiation	--
ENSG00000028116	3.255	3.799	3.826	2.277	2.806	2.937	122.18	140.17	97.74	60.71	88.03	80.32	VRK2	VRK serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12719]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034599//cellular response to oxidative stress;GO:0043408//regulation of MAPK cascade;GO:0046777//protein autophosphorylation;GO:2000659//regulation of interleukin-1-mediated signaling pathway	--
ENSG00000028137	0.052	0	0.018	0.018	0	0	4	0	1	1	0	0	TNFRSF1B	TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Endocrine system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04060//Cytokine-cytokine receptor interaction;ko05170//Human immunodeficiency virus 1 infection;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04920//Adipocytokine signaling pathway	K05141;K05141;K05141;K05141;K05141;K05141;K05141	GO:0002947//tumor necrosis factor receptor superfamily complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0035579//specific granule membrane;GO:0043025//neuronal cell body;GO:0043196//varicosity;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043120//tumor necrosis factor binding	GO:0002718//regulation of cytokine production involved in immune response;GO:0002724//regulation of T cell cytokine production;GO:0003176//aortic valve development;GO:0003177//pulmonary valve development;GO:0003332//negative regulation of extracellular matrix constituent secretion;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007568//aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0031641//regulation of myelination;GO:0031643//positive regulation of myelination;GO:0032496//response to lipopolysaccharide;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042129//regulation of T cell proliferation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050728//negative regulation of inflammatory response;GO:0050779//RNA destabilization;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0060548//negative regulation of cell death;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0150077//regulation of neuroinflammatory response;GO:0150079//negative regulation of neuroinflammatory response;GO:0150098//glial cell-neuron signaling;GO:1901215//negative regulation of neuron death;GO:1902339//positive regulation of apoptotic process involved in morphogenesis;GO:2001141//regulation of RNA biosynthetic process	--
ENSG00000028203	13.724	12.013	11.796	8.245	12.038	9.322	855	705	497	318	494	392	VEZT	"vezatin, adherens junctions transmembrane protein [Source:HGNC Symbol;Acc:HGNC:18258]"	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002142//stereocilia ankle link complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0060171//stereocilium membrane	GO:0017022//myosin binding	GO:0098609//cell-cell adhesion	--
ENSG00000028277	0.028	0.057	0.101	0.019	0.206	0.021	1	3	5	2	4	1	POU2F2	POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213]	Human Diseases;Human Diseases	Infectious disease: viral;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko05417//Lipid and atherosclerosis	K09364;K09364	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002335//mature B cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006959//humoral immune response;GO:0032755//positive regulation of interleukin-6 production;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0098586//cellular response to virus"	Pou
ENSG00000028310	6.473	6.792	5.987	6.347	6.288	6.414	345	372	246	260	278	256.81	BRD9	bromodomain containing 9 [Source:HGNC Symbol;Acc:HGNC:25818]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0070577//lysine-acetylated histone binding	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0045596//negative regulation of cell differentiation;GO:1902459//positive regulation of stem cell population maintenance	--
ENSG00000028528	23.608	23.434	23.147	20.057	20.674	32.538	1584	1596	1202	1039	1242	1117	SNX1	sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17917	"GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030904//retromer complex;GO:0030905//retromer, tubulation complex;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle"	GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity;GO:1990459//transferrin receptor binding;GO:1990460//leptin receptor binding	"GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0031623//receptor internalization;GO:0034498//early endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0045732//positive regulation of protein catabolic process;GO:0072673//lamellipodium morphogenesis"	--
ENSG00000028839	11.456	10.847	11.128	8.852	10.155	11.799	623.64	559.79	437.34	280.2	346.34	389.99	TBPL1	TATA-box binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11589]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Transcription	ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko03022//Basal transcription factors	K03120;K03120;K03120;K03120;K03120;K03120	GO:0005634//nucleus;GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm	GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0140223//general transcription initiation factor activity	"GO:0001675//acrosome assembly;GO:0006235//dTTP biosynthetic process;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007289//spermatid nucleus differentiation"	--
ENSG00000029153	1.818	1.925	0.969	1.178	1.33	0.901	152	140	59	55	87	44	ARNTL2	aryl hydrocarbon receptor nuclear translocator like 2 [Source:HGNC Symbol;Acc:HGNC:18984]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0034751//aryl hydrocarbon receptor complex;GO:1990513//CLOCK-BMAL transcription complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0009649//entrainment of circadian clock;GO:0032922//circadian regulation of gene expression;GO:0042753//positive regulation of circadian rhythm;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	bHLH
ENSG00000029363	37.793	27.911	29.793	18.343	21.647	22.248	2747	2079	1463	867	1306	1123	BCLAF1	BCL2 associated transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:16863]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016592//mediator complex;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	Others
ENSG00000029364	15.442	16.556	17.115	12.639	13.982	15.464	1661	1736	1222	972	1250	1185	SLC39A9	solute carrier family 39 member 9 [Source:HGNC Symbol;Acc:HGNC:20182]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14715;K14715	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0030001//metal ion transport;GO:0055085//transmembrane transport	--
ENSG00000029534	0.632	0.186	0.438	0.574	0.689	0.563	49	32	33	60	67	70	ANK1	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K10380	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0014731//spectrin-associated cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0031430//M band;GO:0043005//neuron projection	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0030507//spectrin binding;GO:0044325//transmembrane transporter binding;GO:0051117//ATPase binding	GO:0006887//exocytosis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0051179//localization;GO:0072659//protein localization to plasma membrane	--
ENSG00000029559	0	0	0	0	0	0	0	0	0	0	0	0	IBSP	integrin binding sialoprotein [Source:HGNC Symbol;Acc:HGNC:5341]	Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04512//ECM-receptor interaction	K06253;K06253;K06253;K06253	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031982//vesicle	GO:0003674//molecular_function;GO:0005178//integrin binding;GO:0005515//protein binding	GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030282//bone mineralization;GO:0031214//biomineral tissue development;GO:0045785//positive regulation of cell adhesion;GO:0071363//cellular response to growth factor stimulus	--
ENSG00000029639	3.09	3.334	2.716	3.122	2.672	2.563	179.42	194.57	116.46	134.26	131.07	108.27	TFB1M	"transcription factor B1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17037]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid	"GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0016740//transferase activity;GO:0034246//mitochondrial transcription factor activity"	GO:0000154//rRNA modification;GO:0006364//rRNA processing;GO:0006391//transcription initiation from mitochondrial promoter;GO:0031167//rRNA methylation;GO:0032259//methylation	Others
ENSG00000029725	25.81	22.71	20.23	14.482	16.547	15.387	2262.2	1944.96	1230.17	957.62	1205.97	1008.95	RABEP1	"rabaptin, RAB GTPase binding effector protein 1 [Source:HGNC Symbol;Acc:HGNC:17677]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12480	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity	GO:0006893//Golgi to plasma membrane transport;GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:0061025//membrane fusion;GO:1903441//protein localization to ciliary membrane	--
ENSG00000029993	22.549	26.651	14.603	16.285	17.977	16.009	694	758	438	397	488	348	HMGB3	high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm	"GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008301//DNA binding, bending"	GO:0002376//immune system process;GO:0006310//DNA recombination;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032392//DNA geometric change;GO:0045087//innate immune response;GO:0045578//negative regulation of B cell differentiation;GO:0045638//negative regulation of myeloid cell differentiation	HMG
ENSG00000030066	13.095	12.57	13.339	12.01	11.506	12.923	1365	1305	1039	929	1010	989	NUP160	nucleoporin 160 [Source:HGNC Symbol;Acc:HGNC:18017]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14303;K14303	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0006406//mRNA export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0033036//macromolecule localization;GO:0043170//macromolecule metabolic process;GO:0051028//mRNA transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0072006//nephron development	--
ENSG00000030110	9.687	9.782	10.739	12.657	11.619	12.092	436	443	357	422	442	396	BAK1	BCL2 antagonist/killer 1 [Source:HGNC Symbol;Acc:HGNC:949]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	"Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Folding, sorting and degradation;Cancer: specific types;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko05206//MicroRNAs in cancer;ko04141//Protein processing in endoplasmic reticulum;ko05225//Hepatocellular carcinoma;ko05160//Hepatitis C;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko04210//Apoptosis;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer;ko04215//Apoptosis - multiple species	K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021;K14021	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0031966//mitochondrial membrane;GO:0046930//pore complex;GO:0097136//Bcl-2 family protein complex;GO:0097145//BAK complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:0051400//BH domain binding	GO:0001776//leukocyte homeostasis;GO:0001782//B cell homeostasis;GO:0001783//B cell apoptotic process;GO:0001836//release of cytochrome c from mitochondria;GO:0001974//blood vessel remodeling;GO:0002262//myeloid cell homeostasis;GO:0002352//B cell negative selection;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0007568//aging;GO:0008053//mitochondrial fusion;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0009410//response to xenobiotic stimulus;GO:0009620//response to fungus;GO:0010046//response to mycotoxin;GO:0010225//response to UV-C;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0010332//response to gamma radiation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010629//negative regulation of gene expression;GO:0012501//programmed cell death;GO:0014070//response to organic cyclic compound;GO:0031018//endocrine pancreas development;GO:0031100//animal organ regeneration;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034620//cellular response to unfolded protein;GO:0034644//cellular response to UV;GO:0035108//limb morphogenesis;GO:0042542//response to hydrogen peroxide;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0044346//fibroblast apoptotic process;GO:0045471//response to ethanol;GO:0045862//positive regulation of proteolysis;GO:0046902//regulation of mitochondrial membrane permeability;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0048872//homeostasis of number of cells;GO:0051726//regulation of cell cycle;GO:0051881//regulation of mitochondrial membrane potential;GO:0060068//vagina development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070242//thymocyte apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0080135//regulation of cellular response to stress;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:1903896//positive regulation of IRE1-mediated unfolded protein response	--
ENSG00000030304	0	0.006	0	0	0.021	0	0	1	0	0	3	0	MUSK	muscle associated receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7525]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038062//protein tyrosine kinase collagen receptor activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007528//neuromuscular junction development;GO:0007613//memory;GO:0008582//regulation of synaptic assembly at neuromuscular junction;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0033674//positive regulation of kinase activity;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0046777//protein autophosphorylation;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:2000541//positive regulation of protein geranylgeranylation	--
ENSG00000030419	1.051	0.779	0.567	0.458	0.637	0.816	141	129	83	59	105	79	IKZF2	IKAROS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13177]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000030582	206.837	226.641	219.44	246.847	245.002	239.03	8872	9764	6898	7605	8865	7400	GRN	granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0051087//chaperone binding	GO:0002265//astrocyte activation involved in immune response;GO:0002282//microglial cell activation involved in immune response;GO:0007040//lysosome organization;GO:0007041//lysosomal transport;GO:0007042//lysosomal lumen acidification;GO:0007165//signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0030335//positive regulation of cell migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0048680//positive regulation of axon regeneration;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050821//protein stabilization;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0106016//positive regulation of inflammatory response to wounding;GO:1900426//positive regulation of defense response to bacterium;GO:1902564//negative regulation of neutrophil activation;GO:1903334//positive regulation of protein folding;GO:1903979//negative regulation of microglial cell activation;GO:1905247//positive regulation of aspartic-type peptidase activity;GO:1905673//positive regulation of lysosome organization	--
ENSG00000031003	12.014	9.505	11.224	7.978	8.239	10.43	1253	1019	852	593	698	744	FAM13B	family with sequence similarity 13 member B [Source:HGNC Symbol;Acc:HGNC:1335]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000031081	1.062	1.484	2.003	2.081	1.527	1.338	205	215	149	213	249	188	ARHGAP31	Rho GTPase activating protein 31 [Source:HGNC Symbol;Acc:HGNC:29216]	-	-	-	-	GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection	GO:0005096//GTPase activator activity;GO:0017124//SH3 domain binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000031691	1.468	2.121	1.762	1.009	1.311	1.18	53	77	47	27	40	31	CENPQ	centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0031511//Mis6-Sim4 complex"	GO:0005515//protein binding	GO:0051310//metaphase plate congression;GO:1905342//positive regulation of protein localization to kinetochore	--
ENSG00000031698	46.506	50.299	48.435	48.12	47.408	49.554	1846	2007	1420	1415	1590	1431	SARS1	seryl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:10537]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01875	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004828//serine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006434//seryl-tRNA aminoacylation;GO:0008033//tRNA processing;GO:0016525//negative regulation of angiogenesis;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process;GO:1904046//negative regulation of vascular endothelial growth factor production	--
ENSG00000031823	32.855	31.517	39.46	30.307	32.208	32.128	1293	1336	1089	1051	1121	1032	RANBP3	RAN binding protein 3 [Source:HGNC Symbol;Acc:HGNC:9850]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K15304	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0070412//R-SMAD binding	GO:0006611//protein export from nucleus;GO:0015031//protein transport;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000032219	2.602	2.091	1.732	0.992	2.206	2.186	252	166	90	82	126	114	ARID4A	AT-rich interaction domain 4A [Source:HGNC Symbol;Acc:HGNC:9885]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016580//Sin3 complex;GO:0017053//transcription repressor complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034773//histone H4-K20 trimethylation;GO:0036124//histone H3-K9 trimethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048821//erythrocyte development;GO:0080182//histone H3-K4 trimethylation;GO:0097368//establishment of Sertoli cell barrier;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	ARID
ENSG00000032389	11.06	10.677	12.118	9.916	10.364	9.953	371	371	305	251	302	246	EIPR1	EARP complex and GARP complex interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:12383]	-	-	-	-	GO:0000938//GARP complex;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:1990745//EARP complex	GO:0005515//protein binding	"GO:0016567//protein ubiquitination;GO:0032456//endocytic recycling;GO:0050796//regulation of insulin secretion;GO:1905281//positive regulation of retrograde transport, endosome to Golgi;GO:2001137//positive regulation of endocytic recycling"	--
ENSG00000032444	36.542	39.856	48.272	48.259	44.064	53.51	2375	2273	2041	2041	2278	2343	PNPLA6	patatin like phospholipase domain containing 6 [Source:HGNC Symbol;Acc:HGNC:16268]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K14676	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004622//lysophospholipase activity;GO:0016787//hydrolase activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046475//glycerophospholipid catabolic process	--
ENSG00000032742	7.24	7.101	6.057	5.566	4.609	6.191	383	378	251	201	221	257	IFT88	intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:0097730//non-motile cilium	GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0001822//kidney development;GO:0009740//gibberellic acid mediated signaling pathway;GO:0030030//cell projection organization;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060271//cilium assembly;GO:1902017//regulation of cilium assembly;GO:1905515//non-motile cilium assembly;GO:2000785//regulation of autophagosome assembly	--
ENSG00000033011	19.808	22.037	22.298	25.897	21.42	24.861	734.18	794.93	625.02	713.61	689.08	645.1	ALG1	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:18294]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03842;K03842;K03842	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004578//chitobiosyldiphosphodolichol beta-mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0097502//mannosylation	--
ENSG00000033030	4.814	4.891	3.912	4.549	5.211	5.307	376	353	242	259	334	305	ZCCHC8	zinc finger CCHC-type containing 8 [Source:HGNC Symbol;Acc:HGNC:25265]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0031499//TRAMP complex;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0016076//snRNA catabolic process;GO:0034470//ncRNA processing"	--
ENSG00000033050	9.465	8.296	10.798	9.918	11.42	9.992	745.23	666.94	570.7	524.58	590.41	549.67	ABCF2	ATP binding cassette subfamily F member 2 [Source:HGNC Symbol;Acc:HGNC:71]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K06185	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000033100	25.625	25.77	24.73	24.446	25.587	25.542	2003.44	2062.07	1441.76	1445.47	1676	1483.94	CHPF2	chondroitin polymerizing factor 2 [Source:HGNC Symbol;Acc:HGNC:29270]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K03419;K03419	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000033122	2.323	2.5	2.362	2.19	1.664	2.294	200	164	114	120	111.01	126	LRRC7	leucine rich repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:18531]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000033170	32.034	31.516	38.05	34.681	29.928	38.484	1796	1832	1590	1475	1465	1595	FUT8	fucosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:4019]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko05202//Transcriptional misregulation in cancer;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K00717;K00717;K00717;K00717;K00717	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008424//glycoprotein 6-alpha-L-fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0017124//SH3 domain binding;GO:0046921//alpha-(1->6)-fucosyltransferase activity	GO:0001701//in utero embryonic development;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006491//N-glycan processing;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009312//oligosaccharide biosynthetic process;GO:0010468//regulation of gene expression;GO:0016477//cell migration;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019082//viral protein processing;GO:0033578//protein glycosylation in Golgi;GO:0036071//N-glycan fucosylation;GO:0042355//L-fucose catabolic process;GO:0043112//receptor metabolic process;GO:0046368//GDP-L-fucose metabolic process;GO:1900407//regulation of cellular response to oxidative stress	--
ENSG00000033178	5.975	5.097	5.288	2.712	3.122	4.541	692	490	401	249	329	344	UBA6	ubiquitin like modifier activating enzyme 6 [Source:HGNC Symbol;Acc:HGNC:25581]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10699	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004839//ubiquitin activating enzyme activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016874//ligase activity;GO:0019780//FAT10 activating enzyme activity	GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007612//learning;GO:0007626//locomotory behavior;GO:0016567//protein ubiquitination;GO:0021764//amygdala development;GO:0021766//hippocampus development;GO:0032446//protein modification by small protein conjugation;GO:0060996//dendritic spine development	--
ENSG00000033327	4.655	4.804	4.947	5.316	6.377	4.349	590	612	463	499	608	401	GAB2	GRB2 associated binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14458]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Immune system;Immune system;Development and regeneration;Signal transduction;Cancer: specific types	ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04071//Sphingolipid signaling pathway;ko05220//Chronic myeloid leukemia	K08091;K08091;K08091;K08091;K08091;K08091;K08091	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0030316//osteoclast differentiation;GO:0043306//positive regulation of mast cell degranulation;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000033627	29.726	32.8	34.793	44.611	43.407	37.943	2229	2441	1887	2471	2704	2122	ATP6V0A1	ATPase H+ transporting V0 subunit a1 [Source:HGNC Symbol;Acc:HGNC:865]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154	"GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016607//nuclear speck;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033176//proton-transporting V-type ATPase complex;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0042470//melanosome;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0016241//regulation of macroautophagy;GO:0048388//endosomal lumen acidification;GO:1901998//toxin transport;GO:1902600//proton transmembrane transport	--
ENSG00000033800	12.587	9.958	7.095	5.527	6.662	10.893	942.71	884.68	570.31	477.18	639.52	698.24	PIAS1	protein inhibitor of activated STAT 1 [Source:HGNC Symbol;Acc:HGNC:2752]	Environmental Information Processing;Human Diseases;Genetic Information Processing	"Signal transduction;Infectious disease: viral;Folding, sorting and degradation"	ko04630//JAK-STAT signaling pathway;ko05160//Hepatitis C;ko04120//Ubiquitin mediated proteolysis	K04706;K04706;K04706	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061665//SUMO ligase activity;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0016925//protein sumoylation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033235//positive regulation of protein sumoylation;GO:0042127//regulation of cell population proliferation;GO:0045444//fat cell differentiation	zf-MIZ
ENSG00000033867	4.117	3.1	2.969	2.449	2.898	3.362	482	341	255	218	284	305	SLC4A7	solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0032420//stereocilium;GO:0042995//cell projection	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0035725//sodium ion transmembrane transport;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0060117//auditory receptor cell development;GO:0098656//anion transmembrane transport	--
ENSG00000034053	5.263	5.189	4.953	4.653	5.351	4.55	358	392	235	249	338	242	APBA2	amyloid beta precursor protein binding family A member 2 [Source:HGNC Symbol;Acc:HGNC:579]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0043197//dendritic spine;GO:0098685//Schaffer collateral - CA1 synapse	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001701//in utero embryonic development;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007626//locomotory behavior;GO:0010468//regulation of gene expression;GO:0015031//protein transport;GO:0035264//multicellular organism growth;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000034152	11.437	13.007	15.332	15.6	16.67	11.994	489	599	420	535	530	393	MAP2K3	mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Environmental adaptation;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Cell growth and death;Endocrine and metabolic disease;Immune system;Endocrine system;Signal transduction;Infectious disease: parasitic;Immune system;Sensory system;Cancer: overview;Endocrine system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05132//Salmonella infection;ko04714//Thermogenesis;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko04664//Fc epsilon RI signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04620//Toll-like receptor signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway"	K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432;K04432	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001817//regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007507//heart development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035331//negative regulation of hippo signaling;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038066//p38MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060048//cardiac muscle contraction;GO:0071222//cellular response to lipopolysaccharide;GO:0072709//cellular response to sorbitol;GO:0090398//cellular senescence"	--
ENSG00000034239	0.909	0.575	0.427	0.39	0.239	0.192	27	16	14	9	4	3	EFCAB1	EF-hand calcium binding domain 1 [Source:HGNC Symbol;Acc:HGNC:25678]	-	-	-	-	GO:0005929//cilium	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0003352//regulation of cilium movement;GO:1901317//regulation of flagellated sperm motility	--
ENSG00000034510	403.679	401.51	417.434	376.116	344.988	349.557	3860	3859	2948	2664	2787	2432	TMSB10	thymosin beta 10 [Source:HGNC Symbol;Acc:HGNC:11879]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers	--
ENSG00000034533	3.663	3.38	4.573	4.29	3.803	4.174	204.08	182.08	188	154	162	160	ASTE1	asteroid homolog 1 [Source:HGNC Symbol;Acc:HGNC:25021]	-	-	-	-	-	GO:0004518//nuclease activity;GO:0005515//protein binding	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000034677	7.415	7.583	6.861	7.346	6.665	7.193	618	593	440	431	474	455	RNF19A	"ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13432]"	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0000226//microtubule cytoskeleton organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0099576//regulation of protein catabolic process at postsynapse, modulating synaptic transmission"	--
ENSG00000034693	5.698	4.68	5.697	4.541	4.939	5.627	325	262	240	162	238	226	PEX3	peroxisomal biogenesis factor 3 [Source:HGNC Symbol;Acc:HGNC:8858]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13336	GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0032994//protein-lipid complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030674//protein-macromolecule adaptor activity	GO:0007031//peroxisome organization;GO:0045046//protein import into peroxisome membrane	--
ENSG00000034713	80.222	79.687	85.432	77.092	70.481	71.884	1612	1612	1266	1148	1203	1052	GABARAPL2	GABA type A receptor associated protein like 2 [Source:HGNC Symbol;Acc:HGNC:13291]	Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Cellular Processes	Immune system;Transport and catabolism;Signal transduction;Nervous system;Transport and catabolism;Transport and catabolism	ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04727//GABAergic synapse;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K08341;K08341;K08341;K08341;K08341;K08341	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding;GO:0048487//beta-tubulin binding;GO:0050811//GABA receptor binding;GO:0051117//ATPase binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0032781//positive regulation of ATPase activity;GO:0070972//protein localization to endoplasmic reticulum;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000034971	5.946	4.454	6.093	20.611	17.88	19.563	259	195	196	665	658	620	MYOC	myocilin [Source:HGNC Symbol;Acc:HGNC:7610]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005929//cilium;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0033268//node of Ranvier;GO:0042995//cell projection;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0001968//fibronectin binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0032027//myosin light chain binding;GO:0046872//metal ion binding	GO:0001649//osteoblast differentiation;GO:0001952//regulation of cell-matrix adhesion;GO:0001953//negative regulation of cell-matrix adhesion;GO:0007165//signal transduction;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014734//skeletal muscle hypertrophy;GO:0022011//myelination in peripheral nervous system;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0035024//negative regulation of Rho protein signal transduction;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0038133//ERBB2-ERBB3 signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0045162//clustering of voltage-gated sodium channels;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051901//positive regulation of mitochondrial depolarization;GO:0060348//bone development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000035115	10.361	8.731	9.077	9.789	9.48	10.552	360	279	217	269	286	260	SH3YL1	SH3 and SYLF domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29546]	-	-	-	-	GO:0032587//ruffle membrane	GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0035091//phosphatidylinositol binding	GO:0006661//phosphatidylinositol biosynthetic process;GO:1900027//regulation of ruffle assembly	--
ENSG00000035141	23.77	25.154	25.982	25.983	26.015	26.77	891	946	714	718	803	724	FAM136A	family with sequence similarity 136 member A [Source:HGNC Symbol;Acc:HGNC:25911]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000035403	64.62	64.462	62.322	56.177	60.375	61.256	7815.06	7794.46	5559.57	4995.58	6149.87	5412.95	VCL	vinculin [Source:HGNC Symbol;Acc:HGNC:12665]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Cellular community - eukaryotes	ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells;ko04520//Adherens junction	K05700;K05700;K05700;K05700;K05700;K05700;K05700	GO:0002102//podosome;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0005916//fascia adherens;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0035580//specific granule lumen;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0044291//cell-cell contact zone;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0090636//outer dense plaque of desmosome;GO:0090637//inner dense plaque of desmosome;GO:0110165//cellular anatomical entity;GO:1903561//extracellular vesicle;GO:1904813//ficolin-1-rich granule lumen;GO:1990357//terminal web	GO:0002162//dystroglycan binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0031625//ubiquitin protein ligase binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0002009//morphogenesis of an epithelium;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0030032//lamellipodium assembly;GO:0030334//regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0034333//adherens junction assembly;GO:0034394//protein localization to cell surface;GO:0035633//maintenance of blood-brain barrier;GO:0043297//apical junction assembly;GO:0048675//axon extension;GO:0051893//regulation of focal adhesion assembly;GO:0070527//platelet aggregation;GO:0090136//epithelial cell-cell adhesion;GO:1903140//regulation of establishment of endothelial barrier;GO:1904702//regulation of protein localization to adherens junction	--
ENSG00000035499	1.136	0.862	0.977	0.52	1.176	0.723	59	45	36	20	49	26	DEPDC1B	DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0016477//cell migration;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000035664	0.411	0.624	1.014	0.708	0.641	0.478	23	35	29	29	32	21	DAPK2	death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]	Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Transport and catabolism;Cancer: specific types	ko05200//Pathways in cancer;ko04140//Autophagy - animal;ko05219//Bladder cancer	K08803;K08803;K08803	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0034423//autophagosome lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043276//anoikis;GO:0046777//protein autophosphorylation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:2000424//positive regulation of eosinophil chemotaxis;GO:2001242//regulation of intrinsic apoptotic signaling pathway	--
ENSG00000035681	8.263	8.119	8.889	7.573	8.924	9.656	608	598	479	413	546	517	NSMAF	neutral sphingomyelinase activation associated factor [Source:HGNC Symbol;Acc:HGNC:8017]	Environmental Information Processing	Signal transduction	ko04071//Sphingolipid signaling pathway	K18953	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016230//sphingomyelin phosphodiesterase activator activity	GO:0006672//ceramide metabolic process;GO:0007165//signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0050790//regulation of catalytic activity	--
ENSG00000035687	19.002	17.158	17.424	15.87	15.545	17.661	1007	914	682	623	696	681	ADSS2	adenylosuccinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:292]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K01939;K01939;K01939	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004019//adenylosuccinate synthase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016874//ligase activity;GO:0042301//phosphate ion binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006164//purine nucleotide biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0006531//aspartate metabolic process;GO:0014074//response to purine-containing compound;GO:0044208//'de novo' AMP biosynthetic process;GO:0046040//IMP metabolic process;GO:0060359//response to ammonium ion;GO:0071257//cellular response to electrical stimulus	--
ENSG00000035720	0	0	0	0	0	0	0	0	0	0	0	0	STAP1	signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0001784//phosphotyrosine residue binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity	"GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009617//response to bacterium;GO:0010628//positive regulation of gene expression;GO:0010760//negative regulation of macrophage chemotaxis;GO:0042326//negative regulation of phosphorylation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0071222//cellular response to lipopolysaccharide;GO:1900028//negative regulation of ruffle assembly;GO:1902227//negative regulation of macrophage colony-stimulating factor signaling pathway;GO:1903980//positive regulation of microglial cell activation;GO:1903997//positive regulation of non-membrane spanning protein tyrosine kinase activity;GO:1904140//negative regulation of microglial cell migration;GO:1904151//positive regulation of microglial cell mediated cytotoxicity;GO:2000251//positive regulation of actin cytoskeleton reorganization"	--
ENSG00000035862	337.383	358.071	368.72	384.594	378.457	366.377	23934	25516	19366	20206.99	22765	18963	TIMP2	TIMP metallopeptidase inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11821]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0002020//protease binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008270//zinc ion binding;GO:0030414//peptidase inhibitor activity;GO:0046872//metal ion binding	GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0034097//response to cytokine;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:1905049//negative regulation of metallopeptidase activity	--
ENSG00000035928	12.263	10.408	8.411	5.579	6.92	8.021	1240	1058	628	418	591	590	RFC1	replication factor C subunit 1 [Source:HGNC Symbol;Acc:HGNC:9969]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03430//Mismatch repair	K10754;K10754;K10754	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031391//Elg1 RFC-like complex;GO:0032991//protein-containing complex;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008047//enzyme activator activity;GO:0016887//ATP hydrolysis activity;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0061860//DNA clamp unloader activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0007004//telomere maintenance via telomerase;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity;GO:0090618//DNA clamp unloading"	--
ENSG00000036054	9.806	8.822	7.012	6.122	6.079	6.611	746	674	394	345	391	365	TBC1D23	TBC1 domain family member 23 [Source:HGNC Symbol;Acc:HGNC:25622]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0071203//WASH complex	GO:0005515//protein binding	"GO:0007420//brain development;GO:0016192//vesicle-mediated transport;GO:0031175//neuron projection development;GO:0042147//retrograde transport, endosome to Golgi;GO:0099041//vesicle tethering to Golgi;GO:1990403//embryonic brain development"	--
ENSG00000036257	20.984	20.515	18.902	13.519	15.404	15.949	1350	1341	904	679	874	754	CUL3	cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553]	Genetic Information Processing;Environmental Information Processing	"Folding, sorting and degradation;Signal transduction"	ko04120//Ubiquitin mediated proteolysis;ko04340//Hedgehog signaling pathway	K03869;K03869	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005827//polar microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0004842//ubiquitin-protein transferase activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0031208//POZ domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0000278//mitotic cell cycle;GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0001831//trophectodermal cellular morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007229//integrin-mediated signaling pathway;GO:0007369//gastrulation;GO:0008284//positive regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0017145//stem cell division;GO:0030030//cell projection organization;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031648//protein destabilization;GO:0032467//positive regulation of cytokinesis;GO:0035024//negative regulation of Rho protein signal transduction;GO:0040016//embryonic cleavage;GO:0043149//stress fiber assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044346//fibroblast apoptotic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0048208//COPII vesicle coating;GO:0051301//cell division;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0071630//nuclear protein quality control by the ubiquitin-proteasome system;GO:0072576//liver morphogenesis;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901992//positive regulation of mitotic cell cycle phase transition	--
ENSG00000036448	0.554	0.699	0.551	0.558	0.365	0.956	41	54	29	35	24	48	MYOM2	myomesin 2 [Source:HGNC Symbol;Acc:HGNC:7614]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0031430//M band;GO:0032982//myosin filament	GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0019900//kinase binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0045214//sarcomere organization	--
ENSG00000036473	0	0	0	0	0	0	0	0	0	0	0	0	OTC	ornithine transcarbamylase [Source:HGNC Symbol;Acc:HGNC:8512]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00220//Arginine biosynthesis	K00611;K00611;K00611	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0004585//ornithine carbamoyltransferase activity;GO:0005543//phospholipid binding;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0016743//carboxyl- or carbamoyltransferase activity;GO:0042301//phosphate ion binding;GO:0042802//identical protein binding	GO:0000050//urea cycle;GO:0001889//liver development;GO:0006520//cellular amino acid metabolic process;GO:0006526//arginine biosynthetic process;GO:0006591//ornithine metabolic process;GO:0006593//ornithine catabolic process;GO:0007494//midgut development;GO:0008652//cellular amino acid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0010043//response to zinc ion;GO:0019240//citrulline biosynthetic process;GO:0031667//response to nutrient levels;GO:0032868//response to insulin;GO:0042450//arginine biosynthetic process via ornithine;GO:0055081//anion homeostasis;GO:0070781//response to biotin;GO:0097272//ammonium homeostasis	--
ENSG00000036530	4.208	5.194	5.366	5.099	4.03	3.383	193	177	148	155	157	107	CYP46A1	cytochrome P450 family 46 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2641]	Metabolism	Lipid metabolism	ko00120//Primary bile acid biosynthesis	K07440	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0033781//cholesterol 24-hydroxylase activity;GO:0046872//metal ion binding;GO:0062184//testosterone 16-beta-hydroxylase activity"	GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006707//cholesterol catabolic process;GO:0006805//xenobiotic metabolic process;GO:0007399//nervous system development;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0016125//sterol metabolic process;GO:0042448//progesterone metabolic process;GO:1900271//regulation of long-term synaptic potentiation;GO:1903044//protein localization to membrane raft	--
ENSG00000036549	14.977	10.664	9.13	8.5	10.026	9.213	1426	1058	655	521	753	661	ZZZ3	zinc finger ZZ-type containing 3 [Source:HGNC Symbol;Acc:HGNC:24523]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0070577//lysine-acetylated histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0031063//regulation of histone deacetylation;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	MYB
ENSG00000036565	0	0	0	0	0	0	0	0	0	0	0	0	SLC18A1	solute carrier family 18 member A1 [Source:HGNC Symbol;Acc:HGNC:10934]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Substance dependence;Nervous system;Nervous system;Nervous system;Substance dependence;Substance dependence	ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko04721//Synaptic vesicle cycle;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K08155;K08155;K08155;K08155;K08155;K08155;K08155	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0110165//cellular anatomical entity	GO:0005335//serotonin:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0015844//monoamine transport;GO:0042908//xenobiotic transport;GO:0051610//serotonin uptake;GO:0055085//transmembrane transport	--
ENSG00000036672	5.042	6.289	7.362	8.323	7.049	8.972	305	315	228	319	287	357	USP2	ubiquitin specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:12618]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0030332//cyclin binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007517//muscle organ development;GO:0016579//protein deubiquitination;GO:0032922//circadian regulation of gene expression;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045475//locomotor rhythm;GO:0045931//positive regulation of mitotic cell cycle;GO:0048511//rhythmic process;GO:0048512//circadian behavior;GO:0050821//protein stabilization;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000036828	0.124	0.097	0.062	0.091	0.04	0.029	25.92	20.4	9.54	14.06	7.11	4.45	CASR	calcium sensing receptor [Source:HGNC Symbol;Acc:HGNC:1514]	Organismal Systems;Organismal Systems	Immune system;Endocrine system	"ko04621//NOD-like receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action"	K04612;K04612	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043679//axon terminus	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016597//amino acid binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0001503//ossification;GO:0002931//response to ischemia;GO:0005513//detection of calcium ion;GO:0006874//cellular calcium ion homeostasis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007254//JNK cascade;GO:0007635//chemosensory behavior;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0010038//response to metal ion;GO:0010628//positive regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0032024//positive regulation of insulin secretion;GO:0032781//positive regulation of ATPase activity;GO:0032782//bile acid secretion;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0042311//vasodilation;GO:0045907//positive regulation of vasoconstriction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050927//positive regulation of positive chemotaxis;GO:0051592//response to calcium ion;GO:0051924//regulation of calcium ion transport;GO:0060613//fat pad development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070509//calcium ion import;GO:0071305//cellular response to vitamin D;GO:0071333//cellular response to glucose stimulus;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071456//cellular response to hypoxia;GO:0071774//response to fibroblast growth factor;GO:0090280//positive regulation of calcium ion import;GO:1901653//cellular response to peptide;GO:1902476//chloride transmembrane transport	--
ENSG00000037042	10.222	10.999	10.816	10.952	9.873	8.891	377.82	408.63	295.27	299.85	308.31	239.1	TUBG2	tubulin gamma 2 [Source:HGNC Symbol;Acc:HGNC:12419]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K10389	GO:0000242//pericentriolar material;GO:0000930//gamma-tubulin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000070//mitotic sister chromatid segregation;GO:0000212//meiotic spindle organization;GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0007020//microtubule nucleation;GO:0007052//mitotic spindle organization;GO:0031122//cytoplasmic microtubule organization	--
ENSG00000037241	17.986	20.38	20.256	13.818	13.349	15.828	265	260	221	151	162	170	RPL26L1	ribosomal protein L26 like 1 [Source:HGNC Symbol;Acc:HGNC:17050]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02898;K02898	GO:0005829//cytosol;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0010467//gene expression;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000037280	0	0.008	0	0.017	0.02	0	0	1	0	1	2	0	FLT4	fms related receptor tyrosine kinase 4 [Source:HGNC Symbol;Acc:HGNC:3767]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko05224//Breast cancer	K05097;K05097;K05097;K05097;K05097;K05097;K05097;K05097	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity	GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001944//vasculature development;GO:0001945//lymph vessel development;GO:0001946//lymphangiogenesis;GO:0002040//sprouting angiogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003016//respiratory system process;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008284//positive regulation of cell population proliferation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010595//positive regulation of endothelial cell migration;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0033674//positive regulation of kinase activity;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048286//lung alveolus development;GO:0048514//blood vessel morphogenesis;GO:0060312//regulation of blood vessel remodeling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090037//positive regulation of protein kinase C signaling	--
ENSG00000037474	9.036	8.334	10.458	7.46	8.576	8.089	572	522	483	352	454	369	NSUN2	NOP2/Sun RNA methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:25994]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0033391//chromatoid body;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0016740//transferase activity;GO:0062152//mRNA (cytidine-5-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0001701//in utero embryonic development;GO:0006400//tRNA modification;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008033//tRNA processing;GO:0010793//regulation of mRNA export from nucleus;GO:0030154//cell differentiation;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0033313//meiotic cell cycle checkpoint signaling;GO:0036416//tRNA stabilization;GO:0048820//hair follicle maturation;GO:0051301//cell division;GO:0080009//mRNA methylation;GO:2000736//regulation of stem cell differentiation	--
ENSG00000037637	6.355	6.615	6.582	5.465	7.601	6.569	614	635	456	433	536	514	FBXO42	F-box protein 42 [Source:HGNC Symbol;Acc:HGNC:29249]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000037749	18.466	18.303	17.942	15.717	16.325	16.512	1571	1557	1130	968	1198	1138	MFAP3	microfibril associated protein 3 [Source:HGNC Symbol;Acc:HGNC:7034]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000037757	6.88	6.166	6.926	7.716	8.482	8.426	451	405	334	375	467	403	MRI1	methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K08963;K08963	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042995//cell projection	GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0046523//S-methyl-5-thioribose-1-phosphate isomerase activity	GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0019284//L-methionine salvage from S-adenosylmethionine;GO:0019509//L-methionine salvage from methylthioadenosine;GO:0044237//cellular metabolic process;GO:0044249//cellular biosynthetic process	--
ENSG00000037897	2.376	3.807	3.079	3.502	3.17	3.534	58	96	65	65	70	66	METTL1	"methyltransferase 1, tRNA methylguanosine [Source:HGNC Symbol;Acc:HGNC:7030]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043527//tRNA methyltransferase complex	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008176//tRNA (guanine-N7-)-methyltransferase activity;GO:0016740//transferase activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0036265//RNA (guanine-N7)-methylation;GO:0106004//tRNA (guanine-N7)-methylation	--
ENSG00000037965	0	0.02	0	0	0.047	0	0	1	0	0	2	0	HOXC8	homeobox C8 [Source:HGNC Symbol;Acc:HGNC:5129]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0030182//neuron differentiation;GO:0048705//skeletal system morphogenesis"	Homeobox
ENSG00000038002	28.426	25.855	24.232	25.598	20.876	26.501	918	1035	657	660	729	645	AGA	aspartylglucosaminidase [Source:HGNC Symbol;Acc:HGNC:318]	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K01444;K01444	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0035578//azurophil granule lumen	GO:0003948//N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006517//protein deglycosylation	--
ENSG00000038210	5.575	3.642	4.722	4.711	4.527	4.442	344	263	260	249	270	228	PI4K2B	phosphatidylinositol 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:18215]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K13711;K13711;K13711	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007030//Golgi organization;GO:0007032//endosome organization;GO:0016310//phosphorylation;GO:0044238//primary metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000038219	2.323	1.222	1.141	1.188	1.667	1.286	385	222	134	146	212	176	BOD1L1	biorientation of chromosomes in cell division 1 like 1 [Source:HGNC Symbol;Acc:HGNC:31792]	-	-	-	-	GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0048188//Set1C/COMPASS complex	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031297//replication fork processing;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0051301//cell division;GO:0051568//histone H3-K4 methylation	--
ENSG00000038274	28.803	24.864	29.617	25.127	25.632	30.58	1249	1096	930	812	920	971	MAT2B	methionine adenosyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:6905]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism	K00789;K00789;K00789	GO:0005634//nucleus;GO:0005829//cytosol;GO:0048269//methionine adenosyltransferase complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0048270//methionine adenosyltransferase regulator activity	GO:0006556//S-adenosylmethionine biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000038295	1.024	0.55	0.404	1.66	0.706	0.608	85	70	40	67	72	39	TLL1	tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0006508//proteolysis;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization	--
ENSG00000038358	10.285	10.977	12.571	11.9	11.468	11.398	1017	1091	918	839	958	820	EDC4	enhancer of mRNA decapping 4 [Source:HGNC Symbol;Acc:HGNC:17157]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12616	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding	GO:0008150//biological_process;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA	--
ENSG00000038382	13.941	12.999	13.37	9.869	12.828	12.292	2570	2435	1954	1531	2153	1719	TRIO	trio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0016310//phosphorylation;GO:0045599//negative regulation of fat cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000038427	17.706	13.923	3.958	3.136	6.009	3.85	3625	2784	596	471	1030	568	VCAN	versican [Source:HGNC Symbol;Acc:HGNC:2464]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06793	GO:0001750//photoreceptor outer segment;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0033165//interphotoreceptor matrix;GO:0042995//cell projection;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0005540//hyaluronic acid binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0030246//carbohydrate binding	GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0007417//central nervous system development;GO:0008037//cell recognition;GO:0008347//glial cell migration	--
ENSG00000038532	10.521	10.253	11.155	8.815	10.076	10.396	1048	1124	865	769	958	808	CLEC16A	C-type lectin domain containing 16A [Source:HGNC Symbol;Acc:HGNC:29013]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0036020//endolysosome membrane	GO:0003674//molecular_function	GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0009267//cellular response to starvation;GO:0016197//endosomal transport;GO:1901096//regulation of autophagosome maturation;GO:1901097//negative regulation of autophagosome maturation;GO:1904263//positive regulation of TORC1 signaling;GO:1904766//negative regulation of macroautophagy by TORC1 signaling	--
ENSG00000038945	0	0	0	0	0.063	0	0	0	0	0	4	0	MSR1	macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K06558	GO:0005581//collagen trimer;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034362//low-density lipoprotein particle	GO:0001540//amyloid-beta binding;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0038024//cargo receptor activity	"GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006911//phagocytosis, engulfment;GO:0010629//negative regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010886//positive regulation of cholesterol storage;GO:0030301//cholesterol transport;GO:0034381//plasma lipoprotein particle clearance;GO:0042953//lipoprotein transport;GO:0071407//cellular response to organic cyclic compound;GO:0097242//amyloid-beta clearance"	--
ENSG00000039068	27.575	31.102	26.503	42.732	45.5	39.325	2605	2897	1869	2996	3582	2661	CDH1	cadherin 1 [Source:HGNC Symbol;Acc:HGNC:1748]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signaling molecules and interaction;Cancer: specific types;Signal transduction;Infectious disease: bacterial;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04015//Rap1 signaling pathway;ko04390//Hippo signaling pathway;ko04514//Cell adhesion molecules;ko05226//Gastric cancer;ko04371//Apelin signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05218//Melanoma;ko04520//Adherens junction;ko05213//Endometrial cancer;ko05219//Bladder cancer;ko05216//Thyroid cancer	K05689;K05689;K05689;K05689;K05689;K05689;K05689;K05689;K05689;K05689;K05689;K05689	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0016342//catenin complex;GO:0016600//flotillin complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0043296//apical junction complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0030506//ankyrin binding;GO:0032794//GTPase activating protein binding;GO:0042802//identical protein binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	"GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010033//response to organic substance;GO:0010468//regulation of gene expression;GO:0021983//pituitary gland development;GO:0022408//negative regulation of cell-cell adhesion;GO:0030336//negative regulation of cell migration;GO:0031175//neuron projection development;GO:0034332//adherens junction organization;GO:0042307//positive regulation of protein import into nucleus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071285//cellular response to lithium ion;GO:0071681//cellular response to indole-3-methanol;GO:0072659//protein localization to plasma membrane;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0099576//regulation of protein catabolic process at postsynapse, modulating synaptic transmission"	--
ENSG00000039123	20.765	16.958	15.33	13.234	13.908	14.335	1656.88	1319.07	885.98	740.72	946.05	839.42	MTREX	Mtr4 exosome RNA helicase [Source:HGNC Symbol;Acc:HGNC:18734]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12598	GO:0000176//nuclear exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0031499//TRAMP complex;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0006401//RNA catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0016076//snRNA catabolic process"	--
ENSG00000039139	0.04	0.049	0.05	0.012	0.022	0.047	13	16	12	3	6	11	DNAH5	dynein axonemal heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:2950]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007018//microtubule-based movement;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0021670//lateral ventricle development;GO:0030317//flagellated sperm motility;GO:0036158//outer dynein arm assembly;GO:0051649//establishment of localization in cell;GO:0060271//cilium assembly	--
ENSG00000039319	13.751	9.073	9.946	7.932	9.071	10.857	2204	1569	1238	960	1224	1244	ZFYVE16	zinc finger FYVE-type containing 16 [Source:HGNC Symbol;Acc:HGNC:20756]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04350//TGF-beta signaling pathway	K04679;K04679	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding"	GO:0006622//protein targeting to lysosome;GO:0007165//signal transduction;GO:0016050//vesicle organization;GO:0016197//endosomal transport;GO:0030100//regulation of endocytosis	--
ENSG00000039523	16.907	21.375	22.645	20.152	22.341	23.626	1359	1537	1151	1086	1433	1233	RIPOR1	RHO family interacting cell polarization regulator 1 [Source:HGNC Symbol;Acc:HGNC:25836]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0071889//14-3-3 protein binding	GO:0007266//Rho protein signal transduction;GO:0009267//cellular response to starvation;GO:0009611//response to wounding;GO:0030335//positive regulation of cell migration;GO:0034067//protein localization to Golgi apparatus;GO:0035024//negative regulation of Rho protein signal transduction;GO:0051683//establishment of Golgi localization;GO:0090316//positive regulation of intracellular protein transport;GO:1990869//cellular response to chemokine;GO:2001107//negative regulation of Rho guanyl-nucleotide exchange factor activity	--
ENSG00000039537	0.196	0.144	0.159	0.018	0.062	0.018	15	11	9	1	4	1	C6	complement C6 [Source:HGNC Symbol;Acc:HGNC:1339]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko04610//Complement and coagulation cascades	K03995;K03995;K03995;K03995	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	"GO:0001701//in utero embryonic development;GO:0002376//immune system process;GO:0006955//immune response;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response"	--
ENSG00000039560	27.48	21.521	20.116	14.661	16.204	16.987	2384	1979	1358	1020	1234	1123	RAI14	retinoic acid induced 14 [Source:HGNC Symbol;Acc:HGNC:14873]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0030054//cell junction	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0097190//apoptotic signaling pathway;GO:1901222//regulation of NIK/NF-kappaB signaling	--
ENSG00000039600	0.018	0	0	0.079	0	0	1	0	0	4	0	0	SOX30	SRY-box transcription factor 30 [Source:HGNC Symbol;Acc:HGNC:30635]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010369//chromocenter;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007286//spermatid development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031960//response to corticosteroid;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0120211//proacrosomal vesicle fusion	HMG
ENSG00000039650	14.449	14.76	17.683	16.741	17.525	13.407	504	528	453	438	526	347	PNKP	polynucleotide kinase 3'-phosphatase [Source:HGNC Symbol;Acc:HGNC:9154]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0035861//site of double-strand break	GO:0000166//nucleotide binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003824//catalytic activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0017076//purine nucleotide binding;GO:0046403//polynucleotide 3'-phosphatase activity;GO:0046404//polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0051734//polynucleotide kinase activity	"GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006259//DNA metabolic process;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0008152//metabolic process;GO:0009314//response to radiation;GO:0010836//negative regulation of protein ADP-ribosylation;GO:0016310//phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0046939//nucleotide phosphorylation;GO:0051103//DNA ligation involved in DNA repair;GO:0051973//positive regulation of telomerase activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0098506//polynucleotide 3' dephosphorylation;GO:1904355//positive regulation of telomere capping;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000039987	0	0	0	0	0	0	0	0	0	0	0	0	BEST2	bestrophin 2 [Source:HGNC Symbol;Acc:HGNC:17107]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13879	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0003674//molecular_function;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0051899//membrane depolarization	--
ENSG00000040199	7.452	7.22	7.393	6.606	7.126	6.817	1131.77	1146.74	874.06	784.06	968.53	785.39	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:29149]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K16340	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0042622//photoreceptor outer segment membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0016311//dephosphorylation;GO:0021766//hippocampus development	--
ENSG00000040275	8.393	10.665	5.452	5.525	5.269	6.266	373	334	184	162	215	130	SPDL1	spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton"	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0043515//kinetochore binding	GO:0000132//establishment of mitotic spindle orientation;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0016477//cell migration;GO:0034501//protein localization to kinetochore;GO:0051301//cell division	--
ENSG00000040341	19.344	16.646	17.325	15.564	16.712	17.23	1120.06	1033.07	703.67	632.02	802.12	683.82	STAU2	staufen double-stranded RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:11371]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0032839//dendrite cytoplasm;GO:0043025//neuronal cell body;GO:0043198//dendritic shaft;GO:1990124//messenger ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0030544//Hsp70 protein binding;GO:0043022//ribosome binding;GO:0051019//mitogen-activated protein kinase binding	GO:0010468//regulation of gene expression;GO:0032956//regulation of actin cytoskeleton organization;GO:0034599//cellular response to oxidative stress;GO:0048592//eye morphogenesis;GO:0051489//regulation of filopodium assembly;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0098964//anterograde dendritic transport of messenger ribonucleoprotein complex;GO:1900454//positive regulation of long-term synaptic depression	--
ENSG00000040487	10.91	11.85	13.795	11.759	11.705	13.288	395	428	330	317	335	361	SLC66A1	solute carrier family 66 member 1 [Source:HGNC Symbol;Acc:HGNC:26001]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015189//L-lysine transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006865//amino acid transport;GO:0015819//lysine transport;GO:0055085//transmembrane transport;GO:0080144//amino acid homeostasis;GO:1903401//L-lysine transmembrane transport;GO:1903826//arginine transmembrane transport;GO:1990822//basic amino acid transmembrane transport	--
ENSG00000040531	30.601	27.202	35.105	30.012	36.552	30.656	1190.02	1186.07	933.02	1036	1108	930.02	CTNS	"cystinosin, lysosomal cystine transporter [Source:HGNC Symbol;Acc:HGNC:2518]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12386	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015184//L-cystine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015295//solute:proton symporter activity	GO:0002088//lens development in camera-type eye;GO:0006520//cellular amino acid metabolic process;GO:0006749//glutathione metabolic process;GO:0006811//ion transport;GO:0007420//brain development;GO:0007616//long-term memory;GO:0007625//grooming behavior;GO:0007628//adult walking behavior;GO:0008542//visual learning;GO:0010730//negative regulation of hydrogen peroxide biosynthetic process;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0015031//protein transport;GO:0015811//L-cystine transport;GO:0042438//melanin biosynthetic process;GO:0046034//ATP metabolic process;GO:0048021//regulation of melanin biosynthetic process;GO:0050890//cognition;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000040608	3.125	2.814	3.526	3.345	4.08	3.904	126	114	105	98	139	113	RTN4R	reticulon 4 receptor [Source:HGNC Symbol;Acc:HGNC:18601]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0044295//axonal growth cone;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008289//lipid binding;GO:0035374//chondroitin sulfate binding;GO:0038023//signaling receptor activity;GO:0038131//neuregulin receptor activity;GO:0044877//protein-containing complex binding;GO:1905573//ganglioside GM1 binding;GO:1905576//ganglioside GT1b binding	GO:0007166//cell surface receptor signaling pathway;GO:0007409//axonogenesis;GO:0010977//negative regulation of neuron projection development;GO:0022038//corpus callosum development;GO:0023041//neuronal signal transduction;GO:0030517//negative regulation of axon extension;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0048681//negative regulation of axon regeneration	--
ENSG00000040633	31.571	33.83	33.473	31.985	34.373	37.972	1023	1058	746	783	913	793	PHF23	PHD finger protein 23 [Source:HGNC Symbol;Acc:HGNC:28428]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006914//autophagy;GO:0031398//positive regulation of protein ubiquitination;GO:1901097//negative regulation of autophagosome maturation;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000040731	0.068	0.05	0.023	0.046	0.017	0	4	3	1	2	1	0	CDH10	cadherin 10 [Source:HGNC Symbol;Acc:HGNC:1749]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099059//integral component of presynaptic active zone membrane;GO:0099060//integral component of postsynaptic specialization membrane	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000040933	3.96	3.866	3.779	3.447	3.851	3.817	583	565	408	360	450	369	INPP4A	inositol polyphosphate-4-phosphatase type I A [Source:HGNC Symbol;Acc:HGNC:6074]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01109;K01109;K01109	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0031901//early endosome membrane;GO:0031965//nuclear membrane;GO:0045202//synapse;GO:0055038//recycling endosome membrane	"GO:0005515//protein binding;GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity;GO:0016787//hydrolase activity;GO:0017161//inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;GO:0052828//inositol-3,4-bisphosphate 4-phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0016311//dephosphorylation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process	--
ENSG00000041353	0.089	0.027	0.056	0.019	0.049	0.095	13	4	6	2	6	10	RAB27B	"RAB27B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9767]"	Organismal Systems	Digestive system	ko04972//Pancreatic secretion	K07886	GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0030141//secretory granule;GO:0030667//secretory granule membrane;GO:0031088//platelet dense granule membrane;GO:0032585//multivesicular body membrane;GO:0042470//melanosome;GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0098993//anchored component of synaptic vesicle membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0019904//protein domain specific binding;GO:0031489//myosin V binding	GO:0017157//regulation of exocytosis;GO:0032402//melanosome transport;GO:0045921//positive regulation of exocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0071985//multivesicular body sorting pathway;GO:0099641//anterograde axonal protein transport	--
ENSG00000041357	48.345	50.231	43.461	40.524	35.41	43.655	1052	1091	720	638	644	711	PSMA4	proteasome 20S subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:9533]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02728;K02728;K02728;K02728;K02728;K02728;K02728;K02728	"GO:0000502//proteasome complex;GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome"	GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000041515	1.819	1.293	1.407	1.204	0.856	1.139	259	185	148	127	103	118	MYO16	myosin XVI [Source:HGNC Symbol;Acc:HGNC:29822]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016459//myosin complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding	GO:0008285//negative regulation of cell population proliferation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0021549//cerebellum development;GO:0048812//neuron projection morphogenesis;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000041802	10.06	9.92	10.24	8.882	8.813	9.224	679	679	515	448	507	457	LSG1	large 60S subunit nuclear export GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25652]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14539	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0000054//ribosomal subunit export from nucleus;GO:0015031//protein transport;GO:0051168//nuclear export	--
ENSG00000041880	6.603	6.226	6.241	6.72	6.803	6.863	307	282	215	224	260	235	PARP3	poly(ADP-ribose) polymerase family member 3 [Source:HGNC Symbol;Acc:HGNC:273]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04210//Apoptosis;ko03410//Base excision repair	K10798;K10798	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0035861//site of double-strand break;GO:0045171//intercellular bridge	GO:0003824//catalytic activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0140294//NAD DNA ADP-ribosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006471//protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus;GO:0030592//DNA ADP-ribosylation;GO:0045829//negative regulation of isotype switching;GO:0051106//positive regulation of DNA ligation;GO:0060236//regulation of mitotic spindle organization;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation;GO:1905662//negative regulation of telomerase RNA reverse transcriptase activity;GO:1990166//protein localization to site of double-strand break;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000041982	0.714	0.546	0.434	0.492	0.408	0.127	87	67	37	36	41	12	TNC	tenascin C [Source:HGNC Symbol;Acc:HGNC:5318]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04512//ECM-receptor interaction	K06252;K06252;K06252;K06252;K06252	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005614//interstitial matrix;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0090733//tenascin complex;GO:0098966//perisynaptic extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0045545//syndecan binding	GO:0001558//regulation of cell growth;GO:0001649//osteoblast differentiation;GO:0002009//morphogenesis of an epithelium;GO:0007155//cell adhesion;GO:0007528//neuromuscular junction development;GO:0008284//positive regulation of cell population proliferation;GO:0009611//response to wounding;GO:0010628//positive regulation of gene expression;GO:0014012//peripheral nervous system axon regeneration;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0042127//regulation of cell population proliferation;GO:0050727//regulation of inflammatory response;GO:0060739//mesenchymal-epithelial cell signaling involved in prostate gland development;GO:0060740//prostate gland epithelium morphogenesis	--
ENSG00000041988	7.218	8.062	6.532	7.879	8.673	8.742	199.51	221.99	129.48	159.67	198.1	173.98	THAP3	THAP domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20855]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0045944//positive regulation of transcription by RNA polymerase II	THAP
ENSG00000042062	0.066	0.066	0	0.044	0.013	0.062	6	6	0	3	1	4	RIPOR3	RIPOR family member 3 [Source:HGNC Symbol;Acc:HGNC:16168]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000042088	8.274	9.75	7.82	7.425	8.195	8.833	416	396	289	229	321	286	TDP1	tyrosyl-DNA phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:18884]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0017005//3'-tyrosyl-DNA phosphodiesterase activity	GO:0000012//single strand break repair;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000042286	5.947	5.874	5.69	6.252	6.245	5.932	379	384	274	298	342	281	AIFM2	apoptosis inducing factor mitochondria associated 2 [Source:HGNC Symbol;Acc:HGNC:21411]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K22745	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	"GO:0003677//DNA binding;GO:0004174//electron-transferring-flavoprotein dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0050660//flavin adenine dinucleotide binding"	GO:0006743//ubiquinone metabolic process;GO:0008637//apoptotic mitochondrial changes;GO:0022904//respiratory electron transport chain;GO:0043065//positive regulation of apoptotic process;GO:0110076//negative regulation of ferroptosis;GO:1900407//regulation of cellular response to oxidative stress	--
ENSG00000042317	8.283	6.305	6.872	6.168	4.77	7.378	309	255	198	161	152	201	SPATA7	spermatogenesis associated 7 [Source:HGNC Symbol;Acc:HGNC:20423]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0120200//rod photoreceptor outer segment;GO:0120206//photoreceptor distal connecting cilium	GO:0005515//protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:1903546//protein localization to photoreceptor outer segment;GO:1903621//protein localization to photoreceptor connecting cilium	--
ENSG00000042429	7.041	7.777	6.866	5.289	8.634	7.427	355.82	404.18	253.5	209.68	356	284.44	MED17	mediator complex subunit 17 [Source:HGNC Symbol;Acc:HGNC:2375]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15133	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000042445	24.922	23.86	23.211	22.204	22.182	23.126	1357	1431	1015	958	1129	1053	RETSAT	retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991]	Metabolism	Metabolism of cofactors and vitamins	ko00830//Retinol metabolism	K09516	GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0031965//nuclear membrane	"GO:0016491//oxidoreductase activity;GO:0051786//all-trans-retinol 13,14-reductase activity"	GO:0006629//lipid metabolic process;GO:0042572//retinol metabolic process	--
ENSG00000042493	10.711	11.066	10.373	10.476	9.693	9.558	266	275	170	189	201	170	CAPG	"capping actin protein, gelsolin like [Source:HGNC Symbol;Acc:HGNC:1474]"	-	-	-	-	GO:0001726//ruffle;GO:0002102//podosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0008290//F-actin capping protein complex;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042470//melanosome;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0090543//Flemming body	"GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019904//protein domain specific binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding"	GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0030031//cell projection assembly;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping;GO:0065003//protein-containing complex assembly	--
ENSG00000042753	38.292	36.809	37.446	43.509	38.997	40.326	617	606	455	528	530	477	AP2S1	adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565]	Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K11827;K11827;K11827;K11827	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030122//AP-2 adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0036020//endolysosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045334//clathrin-coated endocytic vesicle;GO:0071944//cell periphery	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030100//regulation of endocytosis;GO:0048268//clathrin coat assembly;GO:0072583//clathrin-dependent endocytosis;GO:0098884//postsynaptic neurotransmitter receptor internalization	--
ENSG00000042781	0.338	0.258	0.191	0.011	0.065	0.192	98	72	42	3	11	27	USH2A	usherin [Source:HGNC Symbol;Acc:HGNC:12601]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0002141//stereocilia ankle link;GO:0002142//stereocilia ankle link complex;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032391//photoreceptor connecting cilium;GO:0032421//stereocilium bundle;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0060171//stereocilium membrane;GO:1990075//periciliary membrane compartment;GO:1990696//USH2 complex	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0017022//myosin binding;GO:0042802//identical protein binding	GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035315//hair cell differentiation;GO:0045184//establishment of protein localization;GO:0045494//photoreceptor cell maintenance;GO:0048496//maintenance of animal organ identity;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus;GO:0060113//inner ear receptor cell differentiation	--
ENSG00000042813	0	0	0	0	0	0	0	0	0	0	0	0	ZPBP	zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0002199//zona pellucida receptor complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0001675//acrosome assembly;GO:0007339//binding of sperm to zona pellucida	--
ENSG00000042832	0.096	0.087	0.022	0.169	0.221	0.094	12	14	2	16	15	11	TG	thyroglobulin [Source:HGNC Symbol;Acc:HGNC:11764]	Human Diseases;Organismal Systems	Immune disease;Endocrine system	ko05320//Autoimmune thyroid disease;ko04918//Thyroid hormone synthesis	K10809;K10809	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006590//thyroid hormone generation;GO:0007165//signal transduction;GO:0015705//iodide transport;GO:0030878//thyroid gland development;GO:0031641//regulation of myelination;GO:0042403//thyroid hormone metabolic process;GO:0042446//hormone biosynthetic process	--
ENSG00000042980	1.015	0.796	0.705	0.483	0.709	0.811	35	41	37	17	27	29	ADAM28	ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206]	-	-	-	-	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007283//spermatogenesis	--
ENSG00000043039	0	0	0	0	0	0	0	0	0	0	0	0	BARX2	BARX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:956]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001502//cartilage condensation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0014902//myotube differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000043093	10.856	7.723	6.928	4.767	7.16	7.483	593	494	331	267	354	343	DCUN1D1	defective in cullin neddylation 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18184]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding	GO:0031396//regulation of protein ubiquitination;GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:2000434//regulation of protein neddylation;GO:2000436//positive regulation of protein neddylation	--
ENSG00000043143	12.579	10.888	12.326	12.023	13.115	14.309	1176	1056	864	974	1043	1022	JADE2	jade family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:22984]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0016570//histone modification;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0051726//regulation of cell cycle;GO:2000278//regulation of DNA biosynthetic process"	--
ENSG00000043355	0.146	0.324	0.264	0.264	0.308	0.134	9	20	12	12	16	6	ZIC2	Zic family member 2 [Source:HGNC Symbol;Acc:HGNC:12873]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0031490//chromatin DNA binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007601//visual perception;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity"	zf-C2H2
ENSG00000043462	0	0	0	0	0.036	0	0	0	0	0	1	0	LCP2	lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Infectious disease: bacterial;Immune system;Immune system;Development and regeneration;Immune system;Immune system	ko04015//Rap1 signaling pathway;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04660//T cell receptor signaling pathway	K07361;K07361;K07361;K07361;K07361;K07361;K07361	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0036398//TCR signalosome;GO:0044853//plasma membrane raft	GO:0005515//protein binding	GO:0006955//immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction;GO:0045576//mast cell activation;GO:0045860//positive regulation of protein kinase activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000043514	6.676	6.062	8.221	6.169	7.67	7.175	216	198	203	145	206	163	TRIT1	tRNA isopentenyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:20286]	Metabolism	Global and overview maps	ko01100//Metabolic pathways	K00791	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046872//metal ion binding;GO:0052381//tRNA dimethylallyltransferase activity"	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0070900//mitochondrial tRNA modification	--
ENSG00000043591	0.063	0.205	0.064	0	0.094	0.131	4	13	3	0	5	6	ADRB1	adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Cardiovascular disease;Circulatory system;Digestive system;Cellular community - eukaryotes;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04970//Salivary secretion;ko04540//Gap junction;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K04141;K04141;K04141;K04141;K04141;K04141;K04141;K04141;K04141;K04141;K04141	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098685//Schaffer collateral - CA1 synapse	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004939//beta-adrenergic receptor activity;GO:0004940//beta1-adrenergic receptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031694//alpha-2A adrenergic receptor binding;GO:0046982//protein heterodimerization activity;GO:0099579//G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	"GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0002024//diet induced thermogenesis;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0009409//response to cold;GO:0031649//heat generation;GO:0040015//negative regulation of multicellular organism growth;GO:0042596//fear response;GO:0043547//positive regulation of GTPase activity;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0045823//positive regulation of heart contraction;GO:0050873//brown fat cell differentiation;GO:0060078//regulation of postsynaptic membrane potential;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000044012	0	0	0	0	0	0	0	0	0	0	0	0	GUCA2B	guanylate cyclase activator 2B [Source:HGNC Symbol;Acc:HGNC:4683]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030250//guanylate cyclase activator activity	GO:0019934//cGMP-mediated signaling;GO:0031284//positive regulation of guanylate cyclase activity	--
ENSG00000044090	15.23	17.035	16.849	15.137	14.962	14.29	1620	1788	1307	1133	1309	1090.75	CUL7	cullin 7 [Source:HGNC Symbol;Acc:HGNC:21024]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10613	GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm;GO:1990393//3M complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0000226//microtubule cytoskeleton organization;GO:0000281//mitotic cytokinesis;GO:0001570//vasculogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001890//placenta development;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007030//Golgi organization;GO:0007088//regulation of mitotic nuclear division;GO:0016567//protein ubiquitination;GO:0050775//positive regulation of dendrite morphogenesis	--
ENSG00000044115	107.796	104.554	109.321	87.049	90.341	96.758	8058	7893	6144	4848	5677	5282	CTNNA1	catenin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2509]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types;Immune system;Infectious disease: bacterial;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types	ko05200//Pathways in cancer;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05213//Endometrial cancer	K05691;K05691;K05691;K05691;K05691;K05691;K05691;K05691	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0005925//focal adhesion;GO:0014704//intercalated disc;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016342//catenin complex;GO:0016600//flotillin complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0017166//vinculin binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0001541//ovarian follicle development;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007406//negative regulation of neuroblast proliferation;GO:0007568//aging;GO:0008584//male gonad development;GO:0014070//response to organic cyclic compound;GO:0016264//gap junction assembly;GO:0016477//cell migration;GO:0031103//axon regeneration;GO:0034613//cellular protein localization;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043297//apical junction assembly;GO:0043627//response to estrogen;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048854//brain morphogenesis;GO:0071681//cellular response to indole-3-methanol;GO:0090136//epithelial cell-cell adhesion;GO:0098609//cell-cell adhesion;GO:1900181//negative regulation of protein localization to nucleus;GO:2000146//negative regulation of cell motility;GO:2001045//negative regulation of integrin-mediated signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000044446	4.482	5.971	5.953	4.948	5.935	5.625	472	632	463	386	528	431	PHKA2	phosphorylase kinase regulatory subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8926]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04910//Insulin signaling pathway;ko04922//Glucagon signaling pathway	K07190;K07190;K07190	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005964//phosphorylase kinase complex;GO:0016020//membrane	GO:0004689//phosphorylase kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation	--
ENSG00000044459	1.259	0.854	0.753	0.748	0.945	0.741	136	92	59	59	85	59	CNTLN	centlein [Source:HGNC Symbol;Acc:HGNC:23432]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity	GO:0010457//centriole-centriole cohesion;GO:0033365//protein localization to organelle	--
ENSG00000044524	0.183	0.109	0.154	0.303	0.18	0.151	20	13	12	19	18	13	EPHA3	EPH receptor A3 [Source:HGNC Symbol;Acc:HGNC:3387]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05104	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032956//regulation of actin cytoskeleton organization;GO:0033674//positive regulation of kinase activity;GO:0043087//regulation of GTPase activity;GO:0045806//negative regulation of endocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0051893//regulation of focal adhesion assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071300//cellular response to retinoic acid;GO:0097155//fasciculation of sensory neuron axon;GO:0097156//fasciculation of motor neuron axon;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000044574	221.725	232.936	208.337	229.481	228.311	195.04	13786	14621	9588	10452	11954	8802	HSPA5	heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Organismal Systems;Organismal Systems;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Folding, sorting and degradation;Immune system;Endocrine system;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05020//Prion disease;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04612//Antigen processing and presentation;ko04918//Thyroid hormone synthesis;ko03060//Protein export	K09490;K09490;K09490;K09490;K09490;K09490;K09490;K09490;K09490	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008180//COP9 signalosome;GO:0009986//cell surface;GO:0016020//membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0034663//endoplasmic reticulum chaperone complex;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043022//ribosome binding;GO:0044183//protein folding chaperone;GO:0045296//cadherin binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding	"GO:0001554//luteolysis;GO:0006983//ER overload response;GO:0009314//response to radiation;GO:0010976//positive regulation of neuron projection development;GO:0021589//cerebellum structural organization;GO:0021680//cerebellar Purkinje cell layer development;GO:0021762//substantia nigra development;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031204//posttranslational protein targeting to membrane, translocation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031398//positive regulation of protein ubiquitination;GO:0034620//cellular response to unfolded protein;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0042026//protein refolding;GO:0042149//cellular response to glucose starvation;GO:0042220//response to cocaine;GO:0043066//negative regulation of apoptotic process;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051402//neuron apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0060904//regulation of protein folding in endoplasmic reticulum;GO:0071236//cellular response to antibiotic;GO:0071277//cellular response to calcium ion;GO:0071287//cellular response to manganese ion;GO:0071320//cellular response to cAMP;GO:0071353//cellular response to interleukin-4;GO:0071466//cellular response to xenobiotic stimulus;GO:0071480//cellular response to gamma radiation;GO:0097501//stress response to metal ion;GO:1901998//toxin transport;GO:1903891//regulation of ATF6-mediated unfolded protein response;GO:1903894//regulation of IRE1-mediated unfolded protein response;GO:1903895//negative regulation of IRE1-mediated unfolded protein response;GO:1903897//regulation of PERK-mediated unfolded protein response;GO:1904313//response to methamphetamine hydrochloride;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	--
ENSG00000046604	22.714	18.211	15.881	14.281	16.377	17.783	2684	2163	1386	1250	1635	1529	DSG2	desmoglein 2 [Source:HGNC Symbol;Acc:HGNC:3049]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K07597	GO:0001533//cornified envelope;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	GO:0002934//desmosome organization;GO:0003165//Purkinje myocyte development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential	--
ENSG00000046647	7.926	8.58	8.691	7.322	7.517	5.995	294	278	223	211	215	160	GEMIN8	gem nuclear organelle associated protein 8 [Source:HGNC Symbol;Acc:HGNC:26044]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies	GO:0005515//protein binding	GO:0000387//spliceosomal snRNP assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000046651	3.285	2.358	2.312	1.939	2.496	2.594	264	181	144	115	171	153	OFD1	OFD1 centriole and centriolar satellite protein [Source:HGNC Symbol;Acc:HGNC:2567]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0031514//motile cilium;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0043015//gamma-tubulin binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry	--
ENSG00000046653	11.899	11.161	6.675	2.95	3.605	2.661	923	875	373	125	213	140	GPM6B	glycoprotein M6B [Source:HGNC Symbol;Acc:HGNC:4461]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001503//ossification;GO:0007399//nervous system development;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0031175//neuron projection development;GO:0032956//regulation of actin cytoskeleton organization;GO:0051612//negative regulation of serotonin uptake;GO:0051893//regulation of focal adhesion assembly;GO:0085029//extracellular matrix assembly;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000046774	0	0	0	0	0	0	0	0	0	0	0	0	MAGEC2	MAGE family member C2 [Source:HGNC Symbol;Acc:HGNC:13574]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0044257//cellular protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity	--
ENSG00000046889	0.031	0.049	0.06	0.03	0.095	0.049	7	11	10	5	18	8	PREX2	"phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:22950]"	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008344//adult locomotory behavior;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0035556//intracellular signal transduction;GO:0048813//dendrite morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000047056	7.995	7.532	6.187	8.18	8.088	8.532	717	661	439	521	619	537	WDR37	WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406]	-	-	-	-	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030687//preribosome, large subunit precursor"	GO:0005515//protein binding	-	--
ENSG00000047188	5.346	3.348	3.662	3.121	3.909	4.521	639	434	331	291	421	383	YTHDC2	YTH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24721]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0035770//ribonucleoprotein granule;GO:0048471//perinuclear region of cytoplasm	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008186//ATP-dependent activity, acting on RNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0034458//3'-5' RNA helicase activity;GO:0070063//RNA polymerase binding;GO:1990247//N6-methyladenosine-containing RNA binding"	"GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0034612//response to tumor necrosis factor;GO:0044829//positive regulation by host of viral genome replication;GO:0048477//oogenesis;GO:0048599//oocyte development;GO:0051321//meiotic cell cycle;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:0070555//response to interleukin-1"	--
ENSG00000047230	8.097	8.065	8.788	7.188	6.595	8.871	633	645	512	415	454	508	CTPS2	CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K01937;K01937	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097268//cytoophidium	GO:0000166//nucleotide binding;GO:0003883//CTP synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding	GO:0006220//pyrimidine nucleotide metabolic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0044210//'de novo' CTP biosynthetic process	--
ENSG00000047249	21.118	19.525	21.36	20.201	17.602	22.187	892	843	657	633	635	714	ATP6V1H	ATPase H+ transporting V1 subunit H [Source:HGNC Symbol;Acc:HGNC:18303]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection	K02144;K02144;K02144;K02144;K02144;K02144;K02144;K02144;K02144;K02144;K02144	"GO:0000139//Golgi membrane;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity;GO:0030234//enzyme regulator activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0006897//endocytosis;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0016241//regulation of macroautophagy;GO:0048388//endosomal lumen acidification;GO:0050790//regulation of catalytic activity;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000047315	38.058	35.972	35.315	28.23	29.108	35.143	2862.15	2719.28	1996	1623.25	1865.15	1978.06	POLR2B	RNA polymerase II subunit B [Source:HGNC Symbol;Acc:HGNC:9188]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03010;K03010	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0016020//membrane"	GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0032549//ribonucleoside binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000047346	8.228	7.059	6.255	4.644	5.764	6.422	679	565	375	292	356	348	FAM214A	family with sequence similarity 214 member A [Source:HGNC Symbol;Acc:HGNC:25609]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000047365	1.29	0.747	0.912	0.416	0.638	0.839	201	117	105	48	84	55	ARAP2	"ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:HGNC:16924]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18440	GO:0005737//cytoplasm	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding"	GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity	--
ENSG00000047410	5.133	4.594	2.814	2.183	2.923	4.738	952	630	365	261	478	386	TPR	"translocated promoter region, nuclear basket protein [Source:HGNC Symbol;Acc:HGNC:12017]"	Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases	Cancer: overview;Neurodegenerative disease;Translation;Cancer: specific types	ko05200//Pathways in cancer;ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport;ko05216//Thyroid cancer	K09291;K09291;K09291;K09291	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0042405//nuclear inclusion body;GO:0044615//nuclear pore nuclear basket;GO:0072686//mitotic spindle"	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0017056//structural constituent of nuclear pore;GO:0031072//heat shock protein binding;GO:0042803//protein homodimerization activity;GO:0051019//mitogen-activated protein kinase binding;GO:0070840//dynein complex binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006404//RNA import into nucleus;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0010965//regulation of mitotic sister chromatid separation;GO:0015031//protein transport;GO:0031453//positive regulation of heterochromatin assembly;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0032880//regulation of protein localization;GO:0034605//cellular response to heat;GO:0035457//cellular response to interferon-alpha;GO:0042307//positive regulation of protein import into nucleus;GO:0045947//negative regulation of translational initiation;GO:0046827//positive regulation of protein export from nucleus;GO:0046832//negative regulation of RNA export from nucleus;GO:0051028//mRNA transport;GO:0051301//cell division;GO:0070849//response to epidermal growth factor;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0090316//positive regulation of intracellular protein transport;GO:1901673//regulation of mitotic spindle assembly	--
ENSG00000047457	173.622	157.352	145.685	79.413	104.077	102.397	13198.29	11982.64	8146.68	4680.08	6894.98	5701.48	CP	ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295]	Metabolism;Cellular Processes	Metabolism of cofactors and vitamins;Cell growth and death	ko00860//Porphyrin metabolism;ko04216//Ferroptosis	K13624;K13624	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005765//lysosomal membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000047578	14.982	16.81	16.571	12.929	13.164	14.078	1801	2097	1303	968	1158	942	KATNIP	katanin interacting protein [Source:HGNC Symbol;Acc:HGNC:29068]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0042995//cell projection	-	GO:0090660//cerebrospinal fluid circulation	--
ENSG00000047579	9.458	10.399	10.054	11.249	9.16	10.53	274	301	213	239	222	219	DTNBP1	dystrobrevin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17328]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016528//sarcoplasm;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0030496//midbody;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031083//BLOC-1 complex;GO:0031410//cytoplasmic vesicle;GO:0032279//asymmetric synapse;GO:0033162//melanosome membrane;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0001956//positive regulation of neurotransmitter secretion;GO:0002092//positive regulation of receptor internalization;GO:0006469//negative regulation of protein kinase activity;GO:0006996//organelle organization;GO:0007420//brain development;GO:0007596//blood coagulation;GO:0008089//anterograde axonal transport;GO:0010628//positive regulation of gene expression;GO:0014059//regulation of dopamine secretion;GO:0031175//neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0032091//negative regulation of protein binding;GO:0032438//melanosome organization;GO:0043506//regulation of JUN kinase activity;GO:0048490//anterograde synaptic vesicle transport;GO:0048812//neuron projection morphogenesis;GO:0048813//dendrite morphogenesis;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:0060155//platelet dense granule organization;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0061646//positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:1901215//negative regulation of neuron death;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000047597	3.187	3.3	3.356	3.246	3.64	2.689	342	356	266	258	330	210	XK	X-linked Kx blood group [Source:HGNC Symbol;Acc:HGNC:12811]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005215//transporter activity;GO:0005515//protein binding	GO:0006865//amino acid transport;GO:0006874//cellular calcium ion homeostasis;GO:0008361//regulation of cell size;GO:0010961//cellular magnesium ion homeostasis;GO:0031133//regulation of axon diameter;GO:0042552//myelination;GO:0048741//skeletal muscle fiber development	--
ENSG00000047617	0.681	1.386	0.319	0.654	0.527	0.306	52	57	18	37	34	17	ANO2	anoctamin 2 [Source:HGNC Symbol;Acc:HGNC:1183]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K19497	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0097730//non-motile cilium	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000047621	5.116	4.034	4.09	2.806	3.058	3.684	343	321	220	158	198	203	C12orf4	chromosome 12 open reading frame 4 [Source:HGNC Symbol;Acc:HGNC:1184]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0043304//regulation of mast cell degranulation	--
ENSG00000047634	1.832	1.75	1.807	1.884	1.906	2.393	102	98	75	78	89	97	SCML1	Scm polycomb group protein like 1 [Source:HGNC Symbol;Acc:HGNC:10580]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000047644	11.739	11.499	13.377	10.546	11.291	11.442	1692	1666	1424	1126	1375	1200	WWC3	WWC family member 3 [Source:HGNC Symbol;Acc:HGNC:29237]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0060090//molecular adaptor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0016477//cell migration;GO:0035330//regulation of hippo signaling;GO:0035331//negative regulation of hippo signaling;GO:0046621//negative regulation of organ growth"	--
ENSG00000047648	0.161	0.111	0.084	0.207	0.253	0.158	13	9	5	17	16	9	ARHGAP6	Rho GTPase activating protein 6 [Source:HGNC Symbol;Acc:HGNC:676]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005884//actin filament;GO:0015629//actin cytoskeleton	GO:0005096//GTPase activator activity;GO:0016004//phospholipase activator activity;GO:0017124//SH3 domain binding;GO:0043274//phospholipase binding	GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0007202//activation of phospholipase C activity;GO:0007266//Rho protein signal transduction;GO:0010518//positive regulation of phospholipase activity;GO:0030041//actin filament polymerization;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0048041//focal adhesion assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:0051895//negative regulation of focal adhesion assembly	--
ENSG00000047662	0.049	0	0.05	0.013	0.045	0.04	6.79	0	5.2	1.3	5.26	4.07	FAM184B	family with sequence similarity 184 member B [Source:HGNC Symbol;Acc:HGNC:29235]	-	-	-	-	-	-	-	--
ENSG00000047849	70.014	70.97	67.756	61.17	64.143	56.383	7276	7517	5227	4612	5635	4273	MAP4	microtubule associated protein 4 [Source:HGNC Symbol;Acc:HGNC:6862]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005930//axoneme;GO:0030424//axon;GO:0043005//neuron projection;GO:0072686//mitotic spindle	GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0007052//mitotic spindle organization;GO:0031175//neuron projection development;GO:0051012//microtubule sliding;GO:0051294//establishment of spindle orientation;GO:0051301//cell division;GO:1902856//negative regulation of non-motile cilium assembly	--
ENSG00000047932	10.282	9.112	8.147	7.725	8.054	8.82	979	872	573	544	648	611	GOPC	golgi associated PDZ and coiled-coil motif containing [Source:HGNC Symbol;Acc:HGNC:17643]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030140//trans-Golgi network transport vesicle;GO:0030425//dendrite;GO:0030660//Golgi-associated vesicle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006893//Golgi to plasma membrane transport;GO:0010360//negative regulation of anion channel activity;GO:0015031//protein transport;GO:0043004//cytoplasmic sequestering of CFTR protein;GO:0045176//apical protein localization;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000047936	0	0	0	0	0	0	0	0	0	0	0	0	ROS1	"ROS proto-oncogene 1, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10261]"	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K05088	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding	GO:0001558//regulation of cell growth;GO:0002066//columnar/cuboidal epithelial cell development;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007283//spermatogenesis;GO:0010467//gene expression;GO:0010629//negative regulation of gene expression;GO:0010966//regulation of phosphate transport;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0032006//regulation of TOR signaling;GO:0033674//positive regulation of kinase activity;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0070372//regulation of ERK1 and ERK2 cascade	--
ENSG00000048028	7.648	7.026	7.812	7.037	7.177	8.716	515	457	375	311	375	387	USP28	ubiquitin specific peptidase 28 [Source:HGNC Symbol;Acc:HGNC:12625]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007265//Ras protein signal transduction;GO:0008283//cell population proliferation;GO:0010212//response to ionizing radiation;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability;GO:0034644//cellular response to UV;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	--
ENSG00000048052	17.117	17.197	12.889	8.454	10.365	10.667	1500	1323	815	512	659	631	HDAC9	histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065]	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11409;K11409;K11409	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0035097//histone methyltransferase complex	GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033558//protein deacetylase activity;GO:0034739//histone deacetylase activity (H4-K16 specific);GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001818//negative regulation of cytokine production;GO:0001975//response to amphetamine;GO:0006325//chromatin organization;GO:0006954//inflammatory response;GO:0007507//heart development;GO:0016575//histone deacetylation;GO:0030182//neuron differentiation;GO:0030183//B cell differentiation;GO:0032869//cellular response to insulin stimulus;GO:0034983//peptidyl-lysine deacetylation;GO:0042113//B cell activation;GO:0042632//cholesterol homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048742//regulation of skeletal muscle fiber development;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0051153//regulation of striated muscle cell differentiation;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1990678//histone H4-K16 deacetylation"	--
ENSG00000048140	19.779	20.626	21.747	24.145	22.283	22.222	892	871	707	793	774	675	TSPAN17	tetraspanin 17 [Source:HGNC Symbol;Acc:HGNC:13594]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0019899//enzyme binding	GO:0016567//protein ubiquitination;GO:0051604//protein maturation;GO:0072594//establishment of protein localization to organelle;GO:0072659//protein localization to plasma membrane	--
ENSG00000048162	7.331	6.563	9.079	8.984	7	7.323	131	124.01	124	127.04	111.01	100.04	NOP16	NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding	GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000048342	19.859	18.115	14.713	12.379	12.263	10.926	864	825	545	371	510	379	CC2D2A	coiled-coil and C2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29253]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection	-	GO:0001822//kidney development;GO:0001843//neural tube closure;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0043010//camera-type eye development;GO:0044458//motile cilium assembly;GO:0060271//cilium assembly;GO:1904491//protein localization to ciliary transition zone;GO:1905515//non-motile cilium assembly;GO:1990403//embryonic brain development	--
ENSG00000048392	9.59	7.475	7.792	8.876	7.553	9.88	908	744	549	527	589	584	RRM2B	ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296]	Metabolism;Metabolism;Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Cell growth and death;Metabolism of other amino acids;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko04115//p53 signaling pathway;ko00480//Glutathione metabolism;ko00240//Pyrimidine metabolism	K10808;K10808;K10808;K10808;K10808;K10808	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005971//ribonucleoside-diphosphate reductase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0000731//DNA synthesis involved in DNA repair;GO:0001822//kidney development;GO:0003014//renal system process;GO:0006260//DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0009185//ribonucleoside diphosphate metabolic process;GO:0009200//deoxyribonucleoside triphosphate metabolic process;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0009265//2'-deoxyribonucleotide biosynthetic process;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014075//response to amine;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0070318//positive regulation of G0 to G1 transition;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000048405	4.301	2.992	4.263	3.052	2.914	4.847	334	214	177	152	193	193	ZNF800	zinc finger protein 800 [Source:HGNC Symbol;Acc:HGNC:27267]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000048462	0	0	0	0	0	0	0	0	0	0	0	0	TNFRSF17	TNF receptor superfamily member 17 [Source:HGNC Symbol;Acc:HGNC:11913]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04672//Intestinal immune network for IgA production	K05153;K05153	GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002250//adaptive immune response;GO:0002260//lymphocyte homeostasis;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0033209//tumor necrosis factor-mediated signaling pathway	--
ENSG00000048471	5.321	5.439	4.594	3.472	4.554	3.397	902	919	547	436	589	419	SNX29	sorting nexin 29 [Source:HGNC Symbol;Acc:HGNC:30542]	-	-	-	-	-	GO:0035091//phosphatidylinositol binding	-	--
ENSG00000048540	0.315	0.214	0.94	3.003	1.142	3.047	22	15	21	62	48	60	LMO3	LIM domain only 3 [Source:HGNC Symbol;Acc:HGNC:6643]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000324//positive regulation of glucocorticoid receptor signaling pathway	--
ENSG00000048544	11.777	13.179	9.823	9.732	9.755	11.832	513	577	316	314	359	375	MRPS10	mitochondrial ribosomal protein S10 [Source:HGNC Symbol;Acc:HGNC:14502]	Genetic Information Processing	Translation	ko03010//Ribosome	K02946	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0032543//mitochondrial translation	--
ENSG00000048545	0.31	0.696	0.26	0.534	0.517	0.615	13	26	6	14	12	14	GUCA1A	guanylate cyclase activator 1A [Source:HGNC Symbol;Acc:HGNC:4678]	Organismal Systems	Sensory system	ko04744//Phototransduction	K08328	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0016020//membrane;GO:0042995//cell projection;GO:0097381//photoreceptor disc membrane;GO:0120199//cone photoreceptor outer segment	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0030249//guanylate cyclase regulator activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0031282//regulation of guanylate cyclase activity;GO:0031284//positive regulation of guanylate cyclase activity;GO:0050896//response to stimulus;GO:0071277//cellular response to calcium ion	--
ENSG00000048649	6.689	5.444	5.741	4.07	4.739	3.96	902	594	370	248	418	337	RSF1	remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031213//RSF complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0016584//nucleosome positioning;GO:0031497//chromatin assembly;GO:0043392//negative regulation of DNA binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050434//positive regulation of viral transcription"	--
ENSG00000048707	20.682	18.659	20.134	17.903	17.696	20.454	3814	3763	2698	2275	2633	2564	VPS13D	vacuolar protein sorting 13 homolog D [Source:HGNC Symbol;Acc:HGNC:23595]	-	-	-	-	GO:0019898//extrinsic component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006623//protein targeting to vacuole;GO:0007005//mitochondrion organization;GO:0045053//protein retention in Golgi apparatus;GO:1901526//positive regulation of mitophagy	--
ENSG00000048740	28.258	25.99	25.893	24.257	25.777	25.654	3003	2667	2007	1946	2269	2057	CELF2	CUGBP Elav-like family member 2 [Source:HGNC Symbol;Acc:HGNC:2550]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0090543//Flemming body;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0036002//pre-mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008016//regulation of heart contraction"	--
ENSG00000048828	37.373	39.456	40.14	36.968	39.044	41.551	3345.93	3265.86	2328.84	2218	2704	2305	FAM120A	family with sequence similarity 120A [Source:HGNC Symbol;Acc:HGNC:13247]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003723//RNA binding	-	--
ENSG00000048991	10.519	11.168	8.435	7.69	11.239	9.073	728	690	489	411	601	480	R3HDM1	R3H domain containing 1 [Source:HGNC Symbol;Acc:HGNC:9757]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000049089	558.397	641.328	529.391	364.544	409.017	336.806	32659	37818	22969	15685	20156	14257	COL9A2	collagen type IX alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2218]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K08131;K08131;K08131;K08131;K08131	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005594//collagen type IX trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization	--
ENSG00000049130	1.001	0.759	0.42	0.795	0.776	0.92	114	84	35	68	74	76	KITLG	KIT ligand [Source:HGNC Symbol;Acc:HGNC:6343]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Immune system;Endocrine system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04640//Hematopoietic cell lineage;ko04916//Melanogenesis	K05461;K05461;K05461;K05461;K05461;K05461;K05461;K05461	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0042995//cell projection	GO:0005125//cytokine activity;GO:0005173//stem cell factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001541//ovarian follicle development;GO:0001755//neural crest cell migration;GO:0002687//positive regulation of leukocyte migration;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0033026//negative regulation of mast cell apoptotic process;GO:0035162//embryonic hemopoiesis;GO:0035234//ectopic germ cell programmed cell death;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0045636//positive regulation of melanocyte differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0070668//positive regulation of mast cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1901534//positive regulation of hematopoietic progenitor cell differentiation;GO:1902035//positive regulation of hematopoietic stem cell proliferation	--
ENSG00000049167	3.209	3.759	5.181	3.09	4.348	3.243	227	193	189	130	167	144	ERCC8	"ERCC excision repair 8, CSA ubiquitin ligase complex subunit [Source:HGNC Symbol;Acc:HGNC:3439]"	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Replication and repair"	ko04120//Ubiquitin mediated proteolysis;ko03420//Nucleotide excision repair	K10570;K10570	GO:0000109//nucleotide-excision repair complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0000012//single strand break repair;GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0009411//response to UV;GO:0010165//response to X-ray;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045739//positive regulation of DNA repair;GO:0050896//response to stimulus;GO:0051865//protein autoubiquitination;GO:0090262//regulation of transcription-coupled nucleotide-excision repair;GO:0097680//double-strand break repair via classical nonhomologous end joining	--
ENSG00000049192	0.281	0.272	0.274	0.257	0.117	0.124	42	40	30	28	15	13	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif 6 [Source:HGNC Symbol;Acc:HGNC:222]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0003279//cardiac septum development;GO:0006508//proteolysis;GO:0007507//heart development;GO:0030198//extracellular matrix organization;GO:0035904//aorta development;GO:0060976//coronary vasculature development	--
ENSG00000049239	25.358	27.381	24.636	20.667	25.082	21.604	4546	4840	3303	2788	3880	2925	H6PD	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4795]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00030//Pentose phosphate pathway	K13937;K13937;K13937	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0043231//intracellular membrane-bounded organelle	"GO:0003824//catalytic activity;GO:0004345//glucose-6-phosphate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0016787//hydrolase activity;GO:0017057//6-phosphogluconolactonase activity;GO:0030246//carbohydrate binding;GO:0047934//glucose 1-dehydrogenase (NAD+) activity;GO:0047935//glucose 1-dehydrogenase (NADP+) activity;GO:0047936//glucose 1-dehydrogenase [NAD(P)] activity;GO:0050661//NADP binding"	"GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006098//pentose-phosphate shunt;GO:0006739//NADP metabolic process;GO:0008152//metabolic process;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0097305//response to alcohol;GO:2000064//regulation of cortisol biosynthetic process"	--
ENSG00000049245	67.082	62.989	61.901	56.287	61.086	53.229	2929	2787	2032	1845	2272	1723	VAMP3	vesicle associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:12644]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04145//Phagosome;ko04130//SNARE interactions in vesicular transport	K13505;K13505	GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030133//transport vesicle;GO:0030136//clathrin-coated vesicle;GO:0030141//secretory granule;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding	"GO:0001921//positive regulation of receptor recycling;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035493//SNARE complex assembly;GO:0042147//retrograde transport, endosome to Golgi;GO:0043001//Golgi to plasma membrane protein transport;GO:0061025//membrane fusion;GO:0065003//protein-containing complex assembly;GO:0071346//cellular response to interferon-gamma;GO:1903531//negative regulation of secretion by cell"	--
ENSG00000049246	11.1	10.418	10.33	8.713	9.309	10.702	1447	1363.26	998.08	844	1026	1017	PER3	period circadian regulator 3 [Source:HGNC Symbol;Acc:HGNC:8847]	Organismal Systems;Organismal Systems	Environmental adaptation;Environmental adaptation	ko04713//Circadian entrainment;ko04710//Circadian rhythm	K21945;K21945	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000976//transcription cis-regulatory region binding;GO:0001222//transcription corepressor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031625//ubiquitin protein ligase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0032922//circadian regulation of gene expression;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0048511//rhythmic process;GO:0050821//protein stabilization"	--
ENSG00000049247	0	0.052	0.078	0	0	0	0	1.74	1.92	0	0	0	UTS2	urotensin 2 [Source:HGNC Symbol;Acc:HGNC:12636]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05248	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0045202//synapse	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0008217//regulation of blood pressure;GO:0097746//blood vessel diameter maintenance	--
ENSG00000049249	0.016	0.016	0.022	0.011	0.01	0.045	2	2	2	1	1	4	TNFRSF9	TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05146	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0038023//signaling receptor activity	GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0042127//regulation of cell population proliferation	--
ENSG00000049283	0	0	0	0.027	0.073	0	0	0	0	1	4	0	EPN3	epsin 3 [Source:HGNC Symbol;Acc:HGNC:18235]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12471	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0019897//extrinsic component of plasma membrane;GO:0030125//clathrin vesicle coat;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0030276//clathrin binding;GO:1990175//EH domain binding	GO:0006897//endocytosis	--
ENSG00000049323	80.061	83.191	74.583	57.196	66.321	60.069	8376	8887	5839	4467	5854	4697	LTBP1	latent transforming growth factor beta binding protein 1 [Source:HGNC Symbol;Acc:HGNC:6714]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K19559	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0032991//protein-containing complex;GO:0062023//collagen-containing extracellular matrix	GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0050431//transforming growth factor beta binding;GO:0050436//microfibril binding	GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:1901388//regulation of transforming growth factor beta activation	--
ENSG00000049449	110.526	104.656	102.779	86.888	86.139	97.643	5431	5169	3730	3162.55	3576	3491	RCN1	reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000049540	1148.995	1272.433	1153.186	1313.05	1390.936	1141.154	71959	79352	52704	60350	71616	50746	ELN	elastin [Source:HGNC Symbol;Acc:HGNC:3327]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14211	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0071953//elastic fiber	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0050840//extracellular matrix binding	GO:0003151//outflow tract morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008015//blood circulation;GO:0009887//animal organ morphogenesis;GO:0030198//extracellular matrix organization;GO:0030833//regulation of actin filament polymerization;GO:0043149//stress fiber assembly;GO:0048660//regulation of smooth muscle cell proliferation	--
ENSG00000049541	8.947	10.721	8.919	7.043	7.048	5.932	293	359	227	182	208	139	RFC2	replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03430//Mismatch repair	K10755;K10755;K10755	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex;GO:0031390//Ctf18 RFC-like complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0032508//DNA duplex unwinding;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000049618	22.238	21.067	22.051	18.052	20.09	20.632	3045	2837	2172	1610	2281	2020	ARID1B	AT-rich interaction domain 1B [Source:HGNC Symbol;Acc:HGNC:18040]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11653;K11653	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016514//SWI/SNF complex;GO:0035060//brahma complex;GO:0070603//SWI/SNF superfamily-type complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031491//nucleosome binding	"GO:0002931//response to ischemia;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:1904385//cellular response to angiotensin;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	ARID
ENSG00000049656	46.896	52.931	51.184	58.165	57.1	51.503	2424	2750	1954	2227	2485	1937	CLPTM1L	CLPTM1 like [Source:HGNC Symbol;Acc:HGNC:24308]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process	--
ENSG00000049759	142.754	133.921	118.228	82.101	94.106	101.413	14555	13297	8839	6002	7873	7318	NEDD4L	NEDD4 like E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728]	Cellular Processes;Cellular Processes;Genetic Information Processing;Organismal Systems	"Transport and catabolism;Cellular community - eukaryotes;Folding, sorting and degradation;Excretory system"	ko04144//Endocytosis;ko04530//Tight junction;ko04120//Ubiquitin mediated proteolysis;ko04960//Aldosterone-regulated sodium reabsorption	K13305;K13305;K13305;K13305	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0016740//transferase activity;GO:0017080//sodium channel regulator activity;GO:0019870//potassium channel inhibitor activity;GO:0019871//sodium channel inhibitor activity;GO:0044325//transmembrane transporter binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0003254//regulation of membrane depolarization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0031647//regulation of protein stability;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0048814//regulation of dendrite morphogenesis;GO:0060306//regulation of membrane repolarization;GO:0070936//protein K48-linked ubiquitination;GO:0086005//ventricular cardiac muscle cell action potential;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1902305//regulation of sodium ion transmembrane transport;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:1903861//positive regulation of dendrite extension;GO:2000009//negative regulation of protein localization to cell surface;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:2001288//positive regulation of caveolin-mediated endocytosis	--
ENSG00000049768	0.383	0.1	0.082	0.201	0.101	0.088	4	3	2	7	4	3	FOXP3	forkhead box P3 [Source:HGNC Symbol;Acc:HGNC:6106]	Organismal Systems;Human Diseases	Immune system;Immune disease	ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease	K10163;K10163	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0051525//NFAT protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001782//B cell homeostasis;GO:0001818//negative regulation of cytokine production;GO:0002262//myeloid cell homeostasis;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0002362//CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment;GO:0002456//T cell mediated immunity;GO:0002507//tolerance induction;GO:0002513//tolerance induction to self antigen;GO:0002637//regulation of immunoglobulin production;GO:0002666//positive regulation of T cell tolerance induction;GO:0002667//regulation of T cell anergy;GO:0002669//positive regulation of T cell anergy;GO:0002677//negative regulation of chronic inflammatory response;GO:0002725//negative regulation of T cell cytokine production;GO:0002851//positive regulation of peripheral T cell tolerance induction;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0009314//response to radiation;GO:0009615//response to virus;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014045//establishment of endothelial blood-brain barrier;GO:0031064//negative regulation of histone deacetylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032496//response to lipopolysaccharide;GO:0032689//negative regulation of interferon-gamma production;GO:0032693//negative regulation of interleukin-10 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032713//negative regulation of interleukin-4 production;GO:0032714//negative regulation of interleukin-5 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032753//positive regulation of interleukin-4 production;GO:0032792//negative regulation of CREB transcription factor activity;GO:0032831//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0035066//positive regulation of histone acetylation;GO:0035067//negative regulation of histone acetylation;GO:0042110//T cell activation;GO:0042130//negative regulation of T cell proliferation;GO:0043029//T cell homeostasis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046007//negative regulation of activated T cell proliferation;GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0048513//animal organ development;GO:0050672//negative regulation of lymphocyte proliferation;GO:0050687//negative regulation of defense response to virus;GO:0050728//negative regulation of inflammatory response;GO:0050777//negative regulation of immune response;GO:0050852//T cell receptor signaling pathway;GO:1901355//response to rapamycin;GO:2000320//negative regulation of T-helper 17 cell differentiation"	Fork_head
ENSG00000049769	5.736	2.73	4.927	4.232	4.016	6.547	240	190	232	175	169	246	PPP1R3F	protein phosphatase 1 regulatory subunit 3F [Source:HGNC Symbol;Acc:HGNC:14944]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K17453	GO:0000164//protein phosphatase type 1 complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019903//protein phosphatase binding;GO:2001069//glycogen binding	GO:0005979//regulation of glycogen biosynthetic process;GO:2000465//regulation of glycogen (starch) synthase activity	--
ENSG00000049860	79.245	85.834	77.816	68.936	71.77	74.419	2943	3186	2135	1911.04	2265	2026	HEXB	hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00520//Amino sugar and nucleotide sugar metabolism;ko00513//Various types of N-glycan biosynthesis;ko00531//Glycosaminoglycan degradation;ko00511//Other glycan degradation;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K12373;K12373;K12373;K12373;K12373;K12373;K12373;K12373	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0035578//azurophil granule lumen;GO:0042582//azurophil granule;GO:0043202//lysosomal lumen;GO:0060473//cortical granule;GO:0070062//extracellular exosome;GO:1905379//beta-N-acetylhexosaminidase complex	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0042802//identical protein binding;GO:0102148//N-acetyl-beta-D-galactosaminidase activity"	GO:0001501//skeletal system development;GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0007040//lysosome organization;GO:0007338//single fertilization;GO:0007341//penetration of zona pellucida;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0008049//male courtship behavior;GO:0008152//metabolic process;GO:0008360//regulation of cell shape;GO:0008654//phospholipid biosynthetic process;GO:0009313//oligosaccharide catabolic process;GO:0019915//lipid storage;GO:0019953//sexual reproduction;GO:0030203//glycosaminoglycan metabolic process;GO:0042552//myelination;GO:0043615//astrocyte cell migration;GO:0044267//cellular protein metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048477//oogenesis;GO:0050885//neuromuscular process controlling balance;GO:0050905//neuromuscular process	--
ENSG00000049883	4.578	4.059	3.274	3.453	4.66	4.345	327	298	181	184	255	201	PTCD2	pentatricopeptide repeat domain 2 [Source:HGNC Symbol;Acc:HGNC:25734]	-	-	-	-	GO:0005739//mitochondrion	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0001822//kidney development;GO:0001889//liver development;GO:0006397//mRNA processing;GO:0007005//mitochondrion organization;GO:0007507//heart development;GO:0010468//regulation of gene expression;GO:0050684//regulation of mRNA processing;GO:0055001//muscle cell development;GO:0055010//ventricular cardiac muscle tissue morphogenesis	--
ENSG00000050030	0.75	0.459	0.397	0.289	0.324	0.341	184	118	70	54	70	62	NEXMIF	neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030496//midbody;GO:0072686//mitotic spindle	-	GO:0001953//negative regulation of cell-matrix adhesion;GO:0007399//nervous system development;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2001223//negative regulation of neuron migration	--
ENSG00000050130	30.29	31.27	29.757	27.592	29.137	36.614	945	944	690	612	721	756	JKAMP	JNK1/MAPK8 associated membrane protein [Source:HGNC Symbol;Acc:HGNC:20184]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0006986//response to unfolded protein;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000050165	93.338	102.581	63.797	62.223	71.589	57.972	5009.94	5572.93	2536.38	2470.52	3204.54	2294.59	DKK3	dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0039706//co-receptor binding;GO:0048019//receptor antagonist activity	"GO:0007275//multicellular organism development;GO:0009653//anatomical structure morphogenesis;GO:0016055//Wnt signaling pathway;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030325//adrenal gland development;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1902613//negative regulation of anti-Mullerian hormone signaling pathway;GO:2000065//negative regulation of cortisol biosynthetic process;GO:2000272//negative regulation of signaling receptor activity"	--
ENSG00000050327	12.615	13.549	13.794	12.428	14.991	12.827	1326.54	1418.51	985.76	944.48	1229.44	1030.58	ARHGEF5	Rho guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:13209]	-	-	-	-	GO:0002102//podosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0071944//cell periphery	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008289//lipid binding	GO:0002408//myeloid dendritic cell chemotaxis;GO:0030036//actin cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051493//regulation of cytoskeleton organization;GO:0051496//positive regulation of stress fiber assembly;GO:0061484//hematopoietic stem cell homeostasis;GO:0071803//positive regulation of podosome assembly;GO:0090630//activation of GTPase activity;GO:1904591//positive regulation of protein import	--
ENSG00000050344	5.693	5.62	4.276	4.266	5.289	3.972	441.64	438.2	244.99	245.11	346.61	224.17	NFE2L3	"nuclear factor, erythroid 2 like 3 [Source:HGNC Symbol;Acc:HGNC:7783]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000050393	4.238	4.305	4.137	4.101	5.027	5.652	437	490	346	344	382	356	MCUR1	mitochondrial calcium uniporter regulator 1 [Source:HGNC Symbol;Acc:HGNC:21097]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0036444//calcium import into the mitochondrion;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0070509//calcium ion import	--
ENSG00000050405	12.34	12.298	11.068	8.346	8.31	8.768	900	922	591	458	534	465	LIMA1	LIM domain and actin binding 1 [Source:HGNC Symbol;Acc:HGNC:24636]	-	-	-	-	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0031526//brush border membrane;GO:0032154//cleavage furrow	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016477//cell migration;GO:0030299//intestinal cholesterol absorption;GO:0030835//negative regulation of actin filament depolymerization;GO:0031529//ruffle organization;GO:0042632//cholesterol homeostasis;GO:0051017//actin filament bundle assembly	--
ENSG00000050426	26.22	24.615	26.816	35.795	34.322	25.191	695	721	505	753	726	538	LETMD1	LETM1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24241]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0007005//mitochondrion organization;GO:0050727//regulation of inflammatory response;GO:0050764//regulation of phagocytosis	--
ENSG00000050438	2.335	2.369	3.179	2.556	2.422	2.604	432	391	378	315	384	325	SLC4A8	solute carrier family 4 member 8 [Source:HGNC Symbol;Acc:HGNC:11034]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0032279//asymmetric synapse;GO:0032280//symmetric synapse;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0043679//axon terminus;GO:0097386//glial cell projection;GO:0097457//hippocampal mossy fiber;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005452//inorganic anion exchanger activity;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0015701//bicarbonate transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050801//ion homeostasis;GO:0050804//modulation of chemical synaptic transmission;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1902476//chloride transmembrane transport;GO:2000302//positive regulation of synaptic vesicle exocytosis	--
ENSG00000050555	0.078	0.032	0.061	0.105	0.107	0.027	12	5	7	12	14	3	LAMC3	laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06247;K06247;K06247;K06247;K06247;K06247;K06247;K06247	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016020//membrane;GO:0031012//extracellular matrix	GO:0005198//structural molecule activity	GO:0000904//cell morphogenesis involved in differentiation;GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0014002//astrocyte development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0060041//retina development in camera-type eye	--
ENSG00000050628	0.252	0.367	0.309	0.21	0.296	0.403	31	27	19	16	22	25	PTGER3	prostaglandin E receptor 3 [Source:HGNC Symbol;Acc:HGNC:9595]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Infectious disease: viral;Signal transduction;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K04260;K04260;K04260;K04260;K04260;K04260	GO:0005635//nuclear envelope;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004955//prostaglandin receptor activity;GO:0004957//prostaglandin E receptor activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008150//biological_process;GO:0008219//cell death;GO:0014827//intestine smooth muscle contraction;GO:0031622//positive regulation of fever generation;GO:0050896//response to stimulus;GO:0060455//negative regulation of gastric acid secretion	--
ENSG00000050730	0.031	0.091	0.027	0.037	0	0	1	3	1	1	0	0	TNIP3	TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000050748	15.087	10.972	12.308	12.932	11.552	15.212	869	720	550	587	566	653	MAPK9	mitogen-activated protein kinase 9 [Source:HGNC Symbol;Acc:HGNC:6886]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	"Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Immune system;Cellular community - eukaryotes;Signal transduction;Folding, sorting and degradation;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Transport and catabolism;Nervous system;Infectious disease: viral;Neurodegenerative disease;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Endocrine system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Immune system;Endocrine system;Cancer: specific types;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Endocrine system;Transport and catabolism;Immune system;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Cell growth and death"	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04530//Tight junction;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko05212//Pancreatic cancer;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus;ko04215//Apoptosis - multiple species"	K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004705//JUN kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0010628//positive regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031398//positive regulation of protein ubiquitination;GO:0034614//cellular response to reactive oxygen species;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0046686//response to cadmium ion;GO:0048511//rhythmic process;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0061833//protein localization to tricellular tight junction;GO:0071276//cellular response to cadmium ion;GO:0071803//positive regulation of podosome assembly;GO:0090398//cellular senescence;GO:1901485//positive regulation of transcription factor catabolic process;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000050767	0.423	0.408	0.653	0.684	0.777	0.705	24	23	26	30	38	30	COL23A1	collagen type XXIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22990]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24355	GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0042802//identical protein binding	GO:0030198//extracellular matrix organization	--
ENSG00000050820	60.314	66.493	72.753	74.144	67.523	72.83	3620	3720	3251	3138	3444	3144	BCAR1	"BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971]"	Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Endocrine system;Immune system;Infectious disease: bacterial	"ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells"	K05726;K05726;K05726;K05726;K05726;K05726;K05726;K05726;K05726;K05726	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding	GO:0001558//regulation of cell growth;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0042981//regulation of apoptotic process;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051301//cell division;GO:0060326//cell chemotaxis;GO:0086100//endothelin receptor signaling pathway;GO:0090527//actin filament reorganization	--
ENSG00000051009	4.098	4.743	5.542	4.884	5.238	4.671	287	334	286	253	310	237	FHIP1B	FHF complex subunit HOOK interacting protein 1B [Source:HGNC Symbol;Acc:HGNC:25378]	-	-	-	-	GO:0005829//cytosol;GO:0070695//FHF complex	GO:0005515//protein binding	GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0045022//early endosome to late endosome transport;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000051108	44.598	48.709	46.249	48.877	48.576	64.702	1717	1744	1307	1362	1572	1817	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14027	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:1990037//Lewy body core	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031396//regulation of protein ubiquitination;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0045047//protein targeting to ER;GO:1902235//regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903069//regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000051128	121.997	113.785	146.052	157.066	140.074	168.335	3523.8	3363.7	3139.86	3476.79	3476	3677	HOMER3	homer scaffold protein 3 [Source:HGNC Symbol;Acc:HGNC:17514]	Environmental Information Processing;Organismal Systems	Signal transduction;Nervous system	ko04068//FoxO signaling pathway;ko04724//Glutamatergic synapse	K15010;K15010	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0035256//G protein-coupled glutamate receptor binding;GO:0042802//identical protein binding	GO:0006605//protein targeting;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0032703//negative regulation of interleukin-2 production;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000051180	0.152	0.218	0.247	0.505	0.407	0.641	5	7	6	12	11	11	RAD51	RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Cancer: specific types;Replication and repair;Replication and repair	ko05200//Pathways in cancer;ko05212//Pancreatic cancer;ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K04482;K04482;K04482;K04482	"GO:0000152//nuclear ubiquitin ligase complex;GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016605//PML body;GO:0032991//protein-containing complex;GO:0035861//site of double-strand break;GO:0048471//perinuclear region of cytoplasm"	"GO:0000150//DNA strand exchange activity;GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0070182//DNA polymerase binding"	GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0000730//DNA recombinase assembly;GO:0001932//regulation of protein phosphorylation;GO:0006259//DNA metabolic process;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006312//mitotic recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007127//meiosis I;GO:0007131//reciprocal meiotic recombination;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010165//response to X-ray;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010833//telomere maintenance via telomere lengthening;GO:0014070//response to organic cyclic compound;GO:0031297//replication fork processing;GO:0032200//telomere organization;GO:0035518//histone H2A monoubiquitination;GO:0036297//interstrand cross-link repair;GO:0042148//strand invasion;GO:0051106//positive regulation of DNA ligation;GO:0051321//meiotic cell cycle;GO:0051865//protein autoubiquitination;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0071312//cellular response to alkaloid;GO:0071479//cellular response to ionizing radiation;GO:0071480//cellular response to gamma radiation;GO:0072711//cellular response to hydroxyurea;GO:0072719//cellular response to cisplatin;GO:0072757//cellular response to camptothecin;GO:1904631//response to glucoside;GO:1990414//replication-born double-strand break repair via sister chromatid exchange;GO:1990426//mitotic recombination-dependent replication fork processing;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000051341	0.165	0.104	0.045	0.037	0.111	0.053	30	19	6	5	17	7	POLQ	DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0017116//single-stranded DNA helicase activity;GO:0042802//identical protein binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0032508//DNA duplex unwinding;GO:0051260//protein homooligomerization;GO:0071897//DNA biosynthetic process;GO:0097681//double-strand break repair via alternative nonhomologous end joining;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000051382	7.864	5.602	6.226	5.148	5.588	7.539	703	550	444	375	459	478	PIK3CB	"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:8976]"	Metabolism;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Carbohydrate metabolism;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko01100//Metabolic pathways;ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko00562//Inositol phosphate metabolism;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0016020//membrane;GO:0030496//midbody;GO:0043231//intracellular membrane-bounded organelle"	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0043560//insulin receptor substrate binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0001935//endothelial cell proliferation;GO:0001952//regulation of cell-matrix adhesion;GO:0002931//response to ischemia;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006874//cellular calcium ion homeostasis;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009611//response to wounding;GO:0010508//positive regulation of autophagy;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030168//platelet activation;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0035022//positive regulation of Rac protein signal transduction;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0040016//embryonic cleavage;GO:0043407//negative regulation of MAP kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0051898//negative regulation of protein kinase B signaling;GO:0060055//angiogenesis involved in wound healing;GO:0070527//platelet aggregation;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:1903671//negative regulation of sprouting angiogenesis;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000051523	44.109	40.939	43.998	57.527	49.238	44.966	598	567	413	563	544	435	CYBA	cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Immune system;Cancer: overview;Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Immune system;Infectious disease: parasitic;Cardiovascular disease;Development and regeneration;Immune system	ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04621//NOD-like receptor signaling pathway;ko05140//Leishmaniasis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04670//Leukocyte transendothelial migration	K08009;K08009;K08009;K08009;K08009;K08009;K08009;K08009;K08009;K08009;K08009	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0030670//phagocytic vesicle membrane;GO:0035579//specific granule membrane;GO:0043020//NADPH oxidase complex;GO:0043025//neuronal cell body;GO:0070821//tertiary granule membrane;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0017124//SH3 domain binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0001666//response to hypoxia;GO:0001938//positive regulation of endothelial cell proliferation;GO:0003106//negative regulation of glomerular filtration by angiotensin;GO:0006801//superoxide metabolic process;GO:0006954//inflammatory response;GO:0009410//response to xenobiotic stimulus;GO:0014823//response to activity;GO:0014895//smooth muscle hypertrophy;GO:0017004//cytochrome complex assembly;GO:0022900//electron transport chain;GO:0030307//positive regulation of cell growth;GO:0031667//response to nutrient levels;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032930//positive regulation of superoxide anion generation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0045730//respiratory burst;GO:0045777//positive regulation of blood pressure;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050665//hydrogen peroxide biosynthetic process;GO:0050766//positive regulation of phagocytosis;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0070257//positive regulation of mucus secretion;GO:0070555//response to interleukin-1;GO:0071230//cellular response to amino acid stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0071310//cellular response to organic substance;GO:0071333//cellular response to glucose stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0071480//cellular response to gamma radiation;GO:0072593//reactive oxygen species metabolic process;GO:1900426//positive regulation of defense response to bacterium;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904044//response to aldosterone;GO:1904385//cellular response to angiotensin;GO:1904845//cellular response to L-glutamine	--
ENSG00000051596	25.144	24.569	24.483	21.198	19.589	23.765	817	778	580	508	527	568	THOC3	THO complex 3 [Source:HGNC Symbol;Acc:HGNC:19072]	Genetic Information Processing;Genetic Information Processing	Transcription;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport	K12880;K12880	"GO:0000346//transcription export complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0046784//viral mRNA export from host cell nucleus;GO:0051028//mRNA transport	--
ENSG00000051620	16.127	14.809	16.235	17.567	14.932	16.333	590	563	411	418	445	465	HEBP2	heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0020037//heme binding	GO:0010917//negative regulation of mitochondrial membrane potential;GO:0010940//positive regulation of necrotic cell death;GO:0035794//positive regulation of mitochondrial membrane permeability	--
ENSG00000051825	3.976	2.386	2.178	3.675	1.47	1.854	238	169	91	131	119	150	MPHOSPH9	M-phase phosphoprotein 9 [Source:HGNC Symbol;Acc:HGNC:7215]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding	GO:1902018//negative regulation of cilium assembly	--
ENSG00000052126	5.276	4.823	3.52	2.371	2.777	3.341	443	396	228	135	197	201	PLEKHA5	pleckstrin homology domain containing A5 [Source:HGNC Symbol;Acc:HGNC:30036]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0098978//glutamatergic synapse	"GO:0005515//protein binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0008150//biological_process;GO:0061458//reproductive system development	--
ENSG00000052344	7.73	9.374	8.315	6.895	7.859	8.513	285	359	234	182	253	236	PRSS8	serine protease 8 [Source:HGNC Symbol;Acc:HGNC:9491]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017080//sodium channel regulator activity	GO:0006508//proteolysis;GO:0010765//positive regulation of sodium ion transport	--
ENSG00000052723	8.677	6.458	6.2	5.02	5.96	6.596	989	740	522	424	574	547	SIKE1	suppressor of IKBKE 1 [Source:HGNC Symbol;Acc:HGNC:26119]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12656	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding	-	--
ENSG00000052749	8.541	10.14	9.184	9.841	8.867	7.976	717	807	606	618	613	450	RRP12	ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding	GO:0006364//rRNA processing	--
ENSG00000052795	44.008	34.361	34.96	27.682	29.936	35.217	3948	3048	2161	1848	2276	2296	FNIP2	folliculin interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:29280]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20401	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0042030//ATPase inhibitor activity;GO:0051087//chaperone binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001932//regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0031334//positive regulation of protein-containing complex assembly;GO:0033138//positive regulation of peptidyl-serine phosphorylation	--
ENSG00000052802	50.854	50.066	53.915	58.204	52.742	58.918	2271	2220	1798	1955	2014	1918	MSMO1	methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K07750;K07750	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000254//C-4 methylsterol oxidase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008610//lipid biosynthetic process;GO:0016126//sterol biosynthetic process	--
ENSG00000052841	46.438	41.819	44.858	42.282	43.194	56.061	3984	3505	2756	2640	3070	3406	TTC17	tetratricopeptide repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:25596]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0034044//exomer complex	GO:0005515//protein binding	GO:0006893//Golgi to plasma membrane transport;GO:0030030//cell projection organization;GO:0030041//actin filament polymerization;GO:0044782//cilium organization	--
ENSG00000052850	0	0	0.011	0	0.01	0	0	0	1	0	1	0	ALX4	ALX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:450]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0007517//muscle organ development;GO:0009791//post-embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0035108//limb morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0060021//roof of mouth development"	Homeobox
ENSG00000053108	0.242	0	0.077	0.077	0.043	0.05	8	0	5	5	2	2	FSTL4	follistatin like 4 [Source:HGNC Symbol;Acc:HGNC:21389]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0048403//brain-derived neurotrophic factor binding	GO:0030154//cell differentiation;GO:0031549//negative regulation of brain-derived neurotrophic factor receptor signaling pathway;GO:0048670//regulation of collateral sprouting;GO:0048671//negative regulation of collateral sprouting;GO:0061000//negative regulation of dendritic spine development	--
ENSG00000053254	22.921	16.525	16.604	12.08	16.011	16.483	2797	2304	1648	1401	1762	1541	FOXN3	forkhead box N3 [Source:HGNC Symbol;Acc:HGNC:1928]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0097094//craniofacial suture morphogenesis"	Fork_head
ENSG00000053328	5.436	4.188	3.301	4.252	4.212	4.786	359	278	161	208	235	230	METTL24	methyltransferase like 24 [Source:HGNC Symbol;Acc:HGNC:21566]	-	-	-	-	GO:0005576//extracellular region	GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000053371	53.613	58.757	60.141	68.946	59.888	58.563	1502	1666	1253	1407	1426	1202	AKR7A2	aldo-keto reductase family 7 member A2 [Source:HGNC Symbol;Acc:HGNC:389]	Metabolism	Xenobiotics biodegradation and metabolism	ko00980//Metabolism of xenobiotics by cytochrome P450	K15303	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0019119//phenanthrene-9,10-epoxide hydrolase activity"	GO:0005975//carbohydrate metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0022900//electron transport chain;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process	--
ENSG00000053372	8.259	10.019	9.557	9.466	7.547	9.055	351	428	300	298	271	280	MRTO4	"MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477]"	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000027//ribosomal large subunit assembly;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000053438	3.517	3.003	2.831	2.722	2.316	3.322	87	77	53	51	50	61	NNAT	neuronatin [Source:HGNC Symbol;Acc:HGNC:7860]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007420//brain development;GO:0009249//protein lipoylation;GO:0032024//positive regulation of insulin secretion	--
ENSG00000053501	18.383	15.674	18.954	18.179	15.092	16.679	263	230	212	198	189	185	USE1	unconventional SNARE in the ER 1 [Source:HGNC Symbol;Acc:HGNC:30882]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08507	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex	GO:0005484//SNAP receptor activity;GO:0005515//protein binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007041//lysosomal transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030163//protein catabolic process;GO:0032940//secretion by cell;GO:0061025//membrane fusion"	--
ENSG00000053524	0.043	0.02	0	0.03	0	0	1	2	0	1.39	0	0	MCF2L2	MCF.2 cell line derived transforming sequence-like 2 [Source:HGNC Symbol;Acc:HGNC:30319]	-	-	-	-	GO:0005737//cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000053702	0.21	0.209	0.26	0.212	0.124	0.457	12	12	11	9	6	19	NRIP2	nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding	GO:0006508//proteolysis	--
ENSG00000053747	11.83	11.52	12.193	9.599	10.968	10.866	2078	1912	1475	1282	1626	1424	LAMA3	laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6483]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06240;K06240;K06240;K06240;K06240;K06240;K06240;K06240	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005610//laminin-5 complex;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent	GO:0001738//morphogenesis of a polarized epithelium;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007411//axon guidance;GO:0008544//epidermis development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0035987//endodermal cell differentiation;GO:0045995//regulation of embryonic development;GO:0098609//cell-cell adhesion	--
ENSG00000053770	20.312	17.241	15.347	15.879	15.559	21.366	1633	1310	948	828	979	1048	AP5M1	adaptor related protein complex 5 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:20192]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030119//AP-type membrane coat adaptor complex;GO:0031902//late endosome membrane;GO:0044599//AP-5 adaptor complex	GO:0005515//protein binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport	--
ENSG00000053900	4.366	3.872	3.583	3.829	3.28	3.711	238	212	144	155	151	147	ANAPC4	anaphase promoting complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:19990]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03351;K03351;K03351;K03351;K03351	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0034399//nuclear periphery	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000053918	1.757	3.618	2.377	2.079	3.766	1.007	106	151	65	103	104	49	KCNQ1	potassium voltage-gated channel subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:6294]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Circulatory system;Nervous system;Digestive system;Digestive system;Digestive system;Infectious disease: bacterial	ko04261//Adrenergic signaling in cardiomyocytes;ko04725//Cholinergic synapse;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04971//Gastric acid secretion;ko05110//Vibrio cholerae infection	K04926;K04926;K04926;K04926;K04926;K04926	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034702//ion channel complex;GO:0034705//potassium channel complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045121//membrane raft;GO:0045177//apical part of cell;GO:0097546//ciliary base;GO:1990794//basolateral part of cell	"GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008157//protein phosphatase 1 binding;GO:0015271//outward rectifier potassium channel activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0044325//transmembrane transporter binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0097110//scaffold protein binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization"	GO:0001696//gastric acid secretion;GO:0001698//gastrin-induced gastric acid secretion;GO:0002027//regulation of heart rate;GO:0006006//glucose metabolic process;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0007622//rhythmic behavior;GO:0008016//regulation of heart contraction;GO:0008217//regulation of blood pressure;GO:0010460//positive regulation of heart rate;GO:0010467//gene expression;GO:0010629//negative regulation of gene expression;GO:0015705//iodide transport;GO:0030218//erythrocyte differentiation;GO:0030644//cellular chloride ion homeostasis;GO:0032409//regulation of transporter activity;GO:0032868//response to insulin;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035094//response to nicotine;GO:0035176//social behavior;GO:0035934//corticosterone secretion;GO:0042472//inner ear morphogenesis;GO:0048839//inner ear development;GO:0050892//intestinal absorption;GO:0050905//neuromuscular process;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0060048//cardiac muscle contraction;GO:0060117//auditory receptor cell development;GO:0060306//regulation of membrane repolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0060452//positive regulation of cardiac muscle contraction;GO:0060453//regulation of gastric acid secretion;GO:0061337//cardiac conduction;GO:0062094//stomach development;GO:0070293//renal absorption;GO:0070294//renal sodium ion absorption;GO:0071320//cellular response to cAMP;GO:0071466//cellular response to xenobiotic stimulus;GO:0071805//potassium ion transmembrane transport;GO:0071871//response to epinephrine;GO:0071872//cellular response to epinephrine stimulus;GO:0071875//adrenergic receptor signaling pathway;GO:0072359//circulatory system development;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086009//membrane repolarization;GO:0086011//membrane repolarization during action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086014//atrial cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090102//cochlea development;GO:0097623//potassium ion export across plasma membrane;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:1903817//negative regulation of voltage-gated potassium channel activity;GO:1905150//regulation of voltage-gated sodium channel activity;GO:1905515//non-motile cilium assembly;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000054116	49.991	51.608	56.054	56.713	56.037	60.586	1301	1355	1081	1085	1230	1139	TRAPPC3	trafficking protein particle complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:19942]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0033106//cis-Golgi network membrane;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0048193//Golgi vesicle transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000054118	27.762	28.106	25.961	16.485	21.487	22.015	2329	2298	1613	1054	1506	1366	THRAP3	thyroid hormone receptor associated protein 3 [Source:HGNC Symbol;Acc:HGNC:22964]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0051219//phosphoprotein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006397//mRNA processing;GO:0007623//circadian rhythm;GO:0008380//RNA splicing;GO:0042753//positive regulation of circadian rhythm;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0048255//mRNA stabilization;GO:0048511//rhythmic process"	--
ENSG00000054148	41.351	52.556	51.763	57.583	47.632	51.316	499	635	460	517	484	450	PHPT1	phosphohistidine phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30033]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019855//calcium channel inhibitor activity;GO:0044325//transmembrane transporter binding;GO:0101006//protein histidine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0035971//peptidyl-histidine dephosphorylation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051350//negative regulation of lyase activity;GO:2000147//positive regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000984//negative regulation of ATP citrate synthase activity	--
ENSG00000054179	0.064	0.16	0.227	0.186	0	0.063	2	7	6	6	0	2	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3364]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04742//Taste transduction	K01509;K01509;K01509	GO:0005604//basement membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0045134//uridine-diphosphatase activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009134//nucleoside diphosphate catabolic process;GO:0009181//purine ribonucleoside diphosphate catabolic process;GO:0030168//platelet activation	--
ENSG00000054219	0	0	0	0	0	0.033	0	0	0	0	0	3.44	LY75	lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0006955//immune response	--
ENSG00000054267	6.139	3.895	4.44	2.257	4.838	4.412	630	441.91	316.8	202.77	346.84	332.83	ARID4B	AT-rich interaction domain 4B [Source:HGNC Symbol;Acc:HGNC:15550]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016580//Sin3 complex	GO:0000976//transcription cis-regulatory region binding;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034773//histone H4-K20 trimethylation;GO:0036124//histone H3-K9 trimethylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097368//establishment of Sertoli cell barrier;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	ARID
ENSG00000054277	11.159	10.749	7.531	12.133	13.222	13.365	533.4	499.3	261.32	411.17	531.96	465.29	OPN3	opsin 3 [Source:HGNC Symbol;Acc:HGNC:14007]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005502//11-cis retinal binding;GO:0005503//all-trans retinal binding;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0009583//detection of light stimulus;GO:0009584//detection of visible light;GO:0009637//response to blue light;GO:0018298//protein-chromophore linkage;GO:0030216//keratinocyte differentiation;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0046326//positive regulation of glucose import;GO:0048022//negative regulation of melanin biosynthetic process;GO:0048023//positive regulation of melanin biosynthetic process;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus;GO:0071492//cellular response to UV-A;GO:1901857//positive regulation of cellular respiration	--
ENSG00000054282	8.428	7.21	8.092	7.451	6.401	6.549	432.45	371.83	298.42	283.53	279.91	243.89	SDCCAG8	SHH signaling and ciliogenesis regulator SDCCAG8 [Source:HGNC Symbol;Acc:HGNC:10671]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0030054//cell junction;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097733//photoreceptor cell cilium	GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007098//centrosome cycle;GO:0030010//establishment of cell polarity;GO:0030030//cell projection organization;GO:0031023//microtubule organizing center organization;GO:0035148//tube formation;GO:1902017//regulation of cilium assembly	--
ENSG00000054356	0.182	0.271	0	0.02	0.122	0.063	8	11	0	1	1	1	PTPRN	protein tyrosine phosphatase receptor type N [Source:HGNC Symbol;Acc:HGNC:9676]	Human Diseases	Endocrine and metabolic disease	ko04940//Type I diabetes mellitus	K07817	GO:0005634//nucleus;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030424//axon;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse	GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0016791//phosphatase activity;GO:0030507//spectrin binding;GO:0044389//ubiquitin-like protein ligase binding	GO:0000302//response to reactive oxygen species;GO:0001553//luteinization;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030073//insulin secretion;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1904692//positive regulation of type B pancreatic cell proliferation;GO:1990502//dense core granule maturation	--
ENSG00000054392	1.798	1.225	1.412	1.689	2.025	1.556	135	92	75	84	116	83	HHAT	hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04340//Hedgehog signaling pathway;ko04341//Hedgehog signaling pathway - fly	K24678;K24678	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008374//O-acyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0007224//smoothened signaling pathway;GO:0018009//N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0018345//protein palmitoylation	--
ENSG00000054523	17.763	16.665	17.184	12.541	14.977	15.092	3221	3065	2416	1791	2401	2097	KIF1B	kinesin family member 1B [Source:HGNC Symbol;Acc:HGNC:16636]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding	GO:0006915//apoptotic process;GO:0007018//microtubule-based movement;GO:0007270//neuron-neuron synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0008089//anterograde axonal transport;GO:0016192//vesicle-mediated transport;GO:0030705//cytoskeleton-dependent intracellular transport	--
ENSG00000054598	2.239	2.384	2.442	1.814	1.991	1.913	185	198	149	111	139	115	FOXC1	forkhead box C1 [Source:HGNC Symbol;Acc:HGNC:3800]	-	-	-	-	GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001568//blood vessel development;GO:0001654//eye development;GO:0001657//ureteric bud development;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001822//kidney development;GO:0001945//lymph vessel development;GO:0001958//endochondral ossification;GO:0001974//blood vessel remodeling;GO:0003007//heart morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007420//brain development;GO:0007507//heart development;GO:0008283//cell population proliferation;GO:0008354//germ cell migration;GO:0009653//anatomical structure morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0014031//mesenchymal cell development;GO:0014032//neural crest cell development;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0021549//cerebellum development;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0030203//glycosaminoglycan metabolic process;GO:0032808//lacrimal gland development;GO:0035050//embryonic heart tube development;GO:0036438//maintenance of lens transparency;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043010//camera-type eye development;GO:0043388//positive regulation of DNA binding;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046620//regulation of organ growth;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048341//paraxial mesoderm formation;GO:0048762//mesenchymal cell differentiation;GO:0048844//artery morphogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072010//glomerular epithelium development;GO:0097746//blood vessel diameter maintenance;GO:1901491//negative regulation of lymphangiogenesis;GO:1901534//positive regulation of hematopoietic progenitor cell differentiation;GO:1902038//positive regulation of hematopoietic stem cell differentiation;GO:1902257//negative regulation of apoptotic process involved in outflow tract morphogenesis;GO:1904798//positive regulation of core promoter binding;GO:1990869//cellular response to chemokine"	Fork_head
ENSG00000054611	7.889	9.927	8.04	9.773	7.909	7.935	487	590	388	426	417	375	TBC1D22A	TBC1 domain family member 22A [Source:HGNC Symbol;Acc:HGNC:1309]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0071889//14-3-3 protein binding	GO:0090630//activation of GTPase activity	--
ENSG00000054654	31.431	25.646	16.227	13.942	17.603	18.826	5810	2813	1777	1392	2296	1873	SYNE2	spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030016//myofibril;GO:0030018//Z disc;GO:0030054//cell junction;GO:0031258//lamellipodium membrane;GO:0031527//filopodium membrane;GO:0031965//nuclear membrane;GO:0031981//nuclear lumen;GO:0033017//sarcoplasmic reticulum membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding;GO:0140444//cytoskeleton-nuclear membrane anchor activity	GO:0007097//nuclear migration;GO:0021817//nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration;GO:0030335//positive regulation of cell migration;GO:0031022//nuclear migration along microfilament;GO:0051642//centrosome localization;GO:1902017//regulation of cilium assembly	--
ENSG00000054690	16.018	17.197	13.863	13.052	14.633	13.397	2173.04	2245.56	1342.35	1265	1491	1305.48	PLEKHH1	"pleckstrin homology, MyTH4 and FERM domain containing H1 [Source:HGNC Symbol;Acc:HGNC:17733]"	-	-	-	-	GO:0005856//cytoskeleton	-	-	--
ENSG00000054793	11.694	13.501	11.01	9.794	11.091	9.001	1907	2213	1326	1183	1528	1068	ATP9A	ATPase phospholipid transporting 9A (putative) [Source:HGNC Symbol;Acc:HGNC:13540]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0002020//protease binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140326//ATPase-coupled intramembrane lipid transporter activity	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006897//endocytosis;GO:0015914//phospholipid transport;GO:0034204//lipid translocation;GO:0045332//phospholipid translocation;GO:1903542//negative regulation of exosomal secretion;GO:1905279//regulation of retrograde transport, endosome to Golgi;GO:2001135//regulation of endocytic recycling"	--
ENSG00000054796	0	0	0	0	0	0	0	0	0	0	0	0	SPO11	SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250]	-	-	-	-	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome"	"GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0003918//DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding"	GO:0000706//meiotic DNA double-strand break processing;GO:0001541//ovarian follicle development;GO:0006259//DNA metabolic process;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007292//female gamete generation;GO:0022414//reproductive process;GO:0034502//protein localization to chromosome;GO:0042138//meiotic DNA double-strand break formation;GO:0045141//meiotic telomere clustering;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:1990918//double-strand break repair involved in meiotic recombination	--
ENSG00000054803	0	0	0	0	0	0	0	0	0	0	0	0	CBLN4	cerebellin 4 precursor [Source:HGNC Symbol;Acc:HGNC:16231]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0098982//GABA-ergic synapse	GO:0005515//protein binding	GO:0009306//protein secretion;GO:0099558//maintenance of synapse structure;GO:1904862//inhibitory synapse assembly	--
ENSG00000054938	0	0	0	0	0	0	0	0	0	0	0	0	CHRDL2	chordin like 2 [Source:HGNC Symbol;Acc:HGNC:24168]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0001503//ossification;GO:0030154//cell differentiation;GO:0051216//cartilage development	--
ENSG00000054965	16.611	16.627	16.609	16.493	16.271	16.545	2434	2394	1819	1802	1996	1748	FAM168A	family with sequence similarity 168 member A [Source:HGNC Symbol;Acc:HGNC:28999]	-	-	-	-	-	GO:0005515//protein binding	GO:1905053//positive regulation of base-excision repair	--
ENSG00000054967	1.534	1.579	2.39	2.522	2.634	2.229	92	112	103	124	140	113	RELT	RELT TNF receptor [Source:HGNC Symbol;Acc:HGNC:13764]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05156	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0097186//amelogenesis	--
ENSG00000054983	14.353	16.254	19.528	18.67	19.592	17.375	1075	1237	930	984	1128	900	GALC	galactosylceramidase [Source:HGNC Symbol;Acc:HGNC:4115]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00600//Sphingolipid metabolism	K01202;K01202;K01202	GO:0005764//lysosome;GO:0043202//lysosomal lumen	"GO:0003824//catalytic activity;GO:0004336//galactosylceramidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006683//galactosylceramide catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0008152//metabolic process;GO:0016042//lipid catabolic process;GO:0042552//myelination	--
ENSG00000055044	7.207	6.648	5.585	5.198	7.259	7.079	285	248	153	140	205	179	NOP58	NOP58 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:29926]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14565	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome;GO:0070761//pre-snoRNP complex	GO:0001094//TFIID-class transcription factor complex binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0051117//ATPase binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0048254//snoRNA localization	--
ENSG00000055070	48.335	46.643	51.922	51.196	51.177	51.941	2771	2816	2175	2224	2470	2169	SZRD1	SUZ RNA binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30232]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000055118	2.805	3.108	2.725	2.567	3.719	3.848	187	207	137	132	214	190	KCNH2	potassium voltage-gated channel subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:6251]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:1902937//inward rectifier potassium channel complex	GO:0000976//transcription cis-regulatory region binding;GO:0005216//ion channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0055131//C3HC4-type RING finger domain binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0097110//scaffold protein binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	"GO:0003064//regulation of heart rate by hormone;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0045893//positive regulation of transcription, DNA-templated;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0060048//cardiac muscle contraction;GO:0060306//regulation of membrane repolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071466//cellular response to xenobiotic stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086009//membrane repolarization;GO:0086010//membrane depolarization during action potential;GO:0086011//membrane repolarization during action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903765//negative regulation of potassium ion export across plasma membrane;GO:1990573//potassium ion import across plasma membrane"	--
ENSG00000055130	22.241	19.203	17.7	15.991	15.818	19.127	1432	1217	850	755	866	889	CUL1	cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Genetic Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems	"Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Folding, sorting and degradation;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Signal transduction;Signal transduction;Environmental adaptation"	ko05200//Pathways in cancer;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm	K03347;K03347;K03347;K03347;K03347;K03347;K03347;K03347;K03347;K03347;K03347	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0019005//SCF ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:1990452//Parkin-FBXW7-Cul1 ubiquitin ligase complex	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006915//apoptotic process;GO:0008283//cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000055147	8.614	10.016	7.489	7.529	7.358	7.49	455	494	333	283	293	286	FAM114A2	family with sequence similarity 114 member A2 [Source:HGNC Symbol;Acc:HGNC:1333]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0017076//purine nucleotide binding	GO:0008150//biological_process	--
ENSG00000055163	25.094	25.779	27.969	28.318	28.965	25.195	2480	2645	1990	2042	2348	1797	CYFIP2	cytoplasmic FMR1 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:13760]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04810//Regulation of actin cytoskeleton	K05749;K05749;K05749	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0031209//SCAR complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000902//cell morphogenesis;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0030833//regulation of actin filament polymerization;GO:0031175//neuron projection development;GO:0045862//positive regulation of proteolysis;GO:0048583//regulation of response to stimulus;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0097484//dendrite extension;GO:0098609//cell-cell adhesion	--
ENSG00000055208	37.152	31.95	29.247	24.504	26.877	29.069	3263	2824	1871	1605	2004	1869	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17075]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Development and regeneration;Signal transduction;Infectious disease: parasitic;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05161//Hepatitis B;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway	K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404;K04404	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0007507//heart development;GO:0010507//negative regulation of autophagy;GO:0032496//response to lipopolysaccharide;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045860//positive regulation of protein kinase activity	--
ENSG00000055211	34.976	33.146	31.366	31.568	32.575	33.003	1402	1334	934	945	1111	963	GINM1	glycoprotein integral membrane 1 [Source:HGNC Symbol;Acc:HGNC:21074]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000055332	8.791	6.283	5.739	4.326	5.448	7.087	1348	1010	737	558	766	623	EIF2AK2	eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Human Diseases;Human Diseases	"Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Infectious disease: viral;Infectious disease: viral"	ko05168//Herpes simplex virus 1 infection;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko04141//Protein processing in endoplasmic reticulum;ko04217//Necroptosis;ko05160//Hepatitis C;ko05162//Measles	K16195;K16195;K16195;K16195;K16195;K16195;K16195;K16195;K16195;K16195;K16195;K16195	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019888//protein phosphatase regulator activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0016310//phosphorylation;GO:0017148//negative regulation of translation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032722//positive regulation of chemokine production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0033689//negative regulation of osteoblast proliferation;GO:0034198//cellular response to amino acid starvation;GO:0035455//response to interferon-alpha;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0046777//protein autophosphorylation;GO:0050790//regulation of catalytic activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:1900225//regulation of NLRP3 inflammasome complex assembly;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901532//regulation of hematopoietic progenitor cell differentiation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:1902036//regulation of hematopoietic stem cell differentiation	--
ENSG00000055483	5.16	6.664	6.042	6.379	6.628	7.344	575	627	507	489	611	474	USP36	ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007000//nucleolus organization;GO:0016242//negative regulation of macroautophagy;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability;GO:0042981//regulation of apoptotic process;GO:0050821//protein stabilization;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:2000232//regulation of rRNA processing	--
ENSG00000055609	6.826	4.918	4.371	3.796	4.568	4.646	1508	945	763	549	864	708	KMT2C	lysine methyltransferase 2C [Source:HGNC Symbol;Acc:HGNC:13726]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K09188;K09188	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031981//nuclear lumen;GO:0035097//histone methyltransferase complex;GO:0044666//MLL3/4 complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042393//histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016571//histone methylation;GO:0032259//methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051568//histone H3-K4 methylation;GO:0097692//histone H3-K4 monomethylation"	HMG
ENSG00000055732	5.043	3.872	4.016	3.166	3.904	3.87	294	224	169	131	187	165	MCOLN3	mucolipin TRP cation channel 3 [Source:HGNC Symbol;Acc:HGNC:13358]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K04994	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane	GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0008289//lipid binding;GO:0072345//NAADP-sensitive calcium-release channel activity	GO:0006811//ion transport;GO:0007626//locomotory behavior;GO:0034220//ion transmembrane transport;GO:0042491//inner ear auditory receptor cell differentiation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000055813	0.621	0.466	0.428	0.427	0.652	0.419	53	40	27	27	47	26	CCDC85A	coiled-coil domain containing 85A [Source:HGNC Symbol;Acc:HGNC:29400]	-	-	-	-	GO:0005912//adherens junction;GO:0030054//cell junction	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000055917	35.178	33.003	29.894	27.091	25.138	31.631	3593	2952	2116	1793	2154	2108	PUM2	pumilio RNA binding family member 2 [Source:HGNC Symbol;Acc:HGNC:14958]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K17943	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0062104//pumilio-response element binding;GO:0106222//long noncoding RNA binding	GO:0001501//skeletal system development;GO:0001942//hair follicle development;GO:0006417//regulation of translation;GO:0007005//mitochondrion organization;GO:0010608//posttranscriptional regulation of gene expression;GO:0022904//respiratory electron transport chain;GO:0034063//stress granule assembly;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0043488//regulation of mRNA stability;GO:0051276//chromosome organization;GO:0051983//regulation of chromosome segregation;GO:0060612//adipose tissue development;GO:0060964//regulation of gene silencing by miRNA;GO:1900246//positive regulation of RIG-I signaling pathway;GO:2000637//positive regulation of gene silencing by miRNA	--
ENSG00000055950	45.187	45.382	45.526	47.76	45.84	47.178	840.13	859	645.12	678.41	727.78	654.19	MRPL43	mitochondrial ribosomal protein L43 [Source:HGNC Symbol;Acc:HGNC:14517]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000055955	0	0.048	0.167	0	0.081	0	0	2.59	7.35	0	4.64	0	ITIH4	inter-alpha-trypsin inhibitor heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:6169]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0006953//acute-phase response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process;GO:0034097//response to cytokine	--
ENSG00000055957	0	0	0	0	0	0	0	0	0	0	0	0	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:6166]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process	--
ENSG00000056050	12.132	11.281	14.387	12.311	12.107	11.824	306	286	268	230	258	217	HPF1	histone PARylation factor 1 [Source:HGNC Symbol;Acc:HGNC:26051]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0090734//site of DNA damage	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0072572//poly-ADP-D-ribose binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010835//regulation of protein ADP-ribosylation;GO:0018312//peptidyl-serine ADP-ribosylation;GO:0031056//regulation of histone modification	--
ENSG00000056097	25.455	21.262	22.697	16.34	17.929	20.226	2437	2075	1598	1163	1396	1378	ZFR	zinc finger RNA binding protein [Source:HGNC Symbol;Acc:HGNC:17277]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding	-	--
ENSG00000056277	0.832	0.624	0.549	0.407	0.652	0.801	80	60	39	29	53	43	ZNF280C	zinc finger protein 280C [Source:HGNC Symbol;Acc:HGNC:25955]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Others
ENSG00000056291	0.156	0.098	0	0.209	0	0	4	4	0	5	0	0	NPFFR2	neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K08375	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0031628//opioid receptor binding;GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0009582//detection of abiotic stimulus;GO:0043408//regulation of MAPK cascade;GO:0045761//regulation of adenylate cyclase activity;GO:2000479//regulation of cAMP-dependent protein kinase activity	--
ENSG00000056487	0.238	0.121	0.403	0.075	0.016	0.625	10	10	10	4	1	13	PHF21B	PHD finger protein 21B [Source:HGNC Symbol;Acc:HGNC:25161]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000056558	0.637	0.551	0.665	0.851	0.515	0.77	57	50	44	56	39	50	TRAF1	TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases	Cancer: overview;Cancer: overview;Cancer: overview;Signal transduction;Cell growth and death;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05203//Viral carcinogenesis;ko04064//NF-kappa B signaling pathway;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05222//Small cell lung cancer	K03172;K03172;K03172;K03172;K03172;K03172;K03172	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane	GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0065003//protein-containing complex assembly;GO:0070534//protein K63-linked ubiquitination;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000056586	13.019	12.01	10.474	8.19	9.113	10.675	1880	1570	1071	919	1074	1108	RC3H2	ring finger and CCCH-type domains 2 [Source:HGNC Symbol;Acc:HGNC:21461]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003729//mRNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0035613//RNA stem-loop binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0001782//B cell homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0010608//posttranscriptional regulation of gene expression;GO:0016567//protein ubiquitination;GO:0035264//multicellular organism growth;GO:0042098//T cell proliferation;GO:0043029//T cell homeostasis;GO:0048286//lung alveolus development;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0050852//T cell receptor signaling pathway;GO:0060173//limb development;GO:0061470//T follicular helper cell differentiation;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000628//regulation of miRNA metabolic process"	--
ENSG00000056736	12.809	12.378	15.626	8.329	7.564	13.765	505	501	465	258	256	409	IL17RB	interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04657//IL-17 signaling pathway	K05165;K05165	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0030368//interleukin-17 receptor activity	GO:0001558//regulation of cell growth;GO:0006952//defense response;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000056972	17.223	14.84	19.601	19.5	19.738	20.158	745	656	586	646	761	646	TRAF3IP2	TRAF3 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1343]	Cellular Processes;Organismal Systems	Cell growth and death;Immune system	ko04218//Cellular senescence;ko04657//IL-17 signaling pathway	K21124;K21124	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0001768//establishment of T cell polarity;GO:0001782//B cell homeostasis;GO:0001783//B cell apoptotic process;GO:0001822//kidney development;GO:0002230//positive regulation of defense response to virus by host;GO:0002269//leukocyte activation involved in inflammatory response;GO:0002334//transitional two stage B cell differentiation;GO:0002344//B cell affinity maturation;GO:0002447//eosinophil mediated immunity;GO:0006606//protein import into nucleus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007507//heart development;GO:0009410//response to xenobiotic stimulus;GO:0010467//gene expression;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway;GO:0019724//B cell mediated immunity;GO:0023019//signal transduction involved in regulation of gene expression;GO:0023035//CD40 signaling pathway;GO:0030217//T cell differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034097//response to cytokine;GO:0034504//protein localization to nucleus;GO:0035556//intracellular signal transduction;GO:0038173//interleukin-17A-mediated signaling pathway;GO:0042092//type 2 immune response;GO:0042110//T cell activation;GO:0042119//neutrophil activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043588//skin development;GO:0048255//mRNA stabilization;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0070254//mucus secretion;GO:0070534//protein K63-linked ubiquitination;GO:0071345//cellular response to cytokine stimulus;GO:0072538//T-helper 17 type immune response;GO:0097398//cellular response to interleukin-17;GO:0097400//interleukin-17-mediated signaling pathway;GO:0110012//protein localization to P-body;GO:1990959//eosinophil homeostasis	--
ENSG00000056998	6.853	7.594	8.105	9.598	9.87	8.309	453	502	399	468	494	400	GYG2	glycogenin 2 [Source:HGNC Symbol;Acc:HGNC:4700]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K00750;K00750	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008466//glycogenin glucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:0102751//UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity	GO:0005978//glycogen biosynthetic process	--
ENSG00000057019	45.766	43.367	40.617	35.307	42.253	40.571	5564	5292	3644	3137	4173	3574	DCBLD2	"discoidin, CUB and LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24627]"	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030308//negative regulation of cell growth;GO:0030522//intracellular receptor signaling pathway;GO:0042060//wound healing	--
ENSG00000057149	0	0	0	0	0	0	0	0	0	0	0	0	SERPINB3	serpin family B member 3 [Source:HGNC Symbol;Acc:HGNC:10569]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0008284//positive regulation of cell population proliferation;GO:0010466//negative regulation of peptidase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010950//positive regulation of endopeptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030335//positive regulation of cell migration;GO:0035425//autocrine signaling;GO:0038001//paracrine signaling;GO:0043086//negative regulation of catalytic activity;GO:0043508//negative regulation of JUN kinase activity;GO:0045861//negative regulation of proteolysis;GO:0046718//viral entry into host cell	--
ENSG00000057252	30.832	27.603	28.917	27.553	24.015	32.39	2154	1996	1422	1436	1591	1577	SOAT1	sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]	Organismal Systems;Metabolism	Digestive system;Lipid metabolism	ko04979//Cholesterol metabolism;ko00100//Steroid biosynthesis	K00637;K00637	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000062//fatty-acyl-CoA binding;GO:0004772//sterol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0015485//cholesterol binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0034736//cholesterol O-acyltransferase activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010742//macrophage derived foam cell differentiation;GO:0010878//cholesterol storage;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034383//low-density lipoprotein particle clearance;GO:0034435//cholesterol esterification;GO:0042632//cholesterol homeostasis;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process	--
ENSG00000057294	21.972	18.94	17.757	15.275	17.717	18.893	1879	1632	1130	970	1291	1186	PKP2	plakophilin 2 [Source:HGNC Symbol;Acc:HGNC:9024]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12642	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0014704//intercalated disc;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0019215//intermediate filament binding;GO:0044325//transmembrane transporter binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	GO:0002159//desmosome assembly;GO:0002934//desmosome organization;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007507//heart development;GO:0010765//positive regulation of sodium ion transport;GO:0045110//intermediate filament bundle assembly;GO:0048496//maintenance of animal organ identity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0072659//protein localization to plasma membrane;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential	--
ENSG00000057468	0.059	0	0	0	0	0	4	0	0	0	0	0	MSH4	mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327]	-	-	-	-	GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005713//recombination nodule	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030983//mismatched DNA binding	GO:0001541//ovarian follicle development;GO:0006298//mismatch repair;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000057593	0.117	0.317	0.136	0.204	0.04	0.115	7	11	6	9	2	5	F7	coagulation factor VII [Source:HGNC Symbol;Acc:HGNC:3544]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01320	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031982//vesicle;GO:0062023//collagen-containing extracellular matrix;GO:1905286//serine-type peptidase complex	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0001666//response to hypoxia;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0007623//circadian rhythm;GO:0009725//response to hormone;GO:0010037//response to carbon dioxide;GO:0010641//positive regulation of platelet-derived growth factor receptor signaling pathway;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0030194//positive regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0031100//animal organ regeneration;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0032571//response to vitamin K;GO:0033595//response to genistein;GO:0043627//response to estrogen;GO:0050927//positive regulation of positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0060416//response to growth hormone;GO:0061476//response to anticoagulant;GO:0070723//response to cholesterol;GO:0097066//response to thyroid hormone;GO:0097068//response to thyroxine;GO:1904400//response to Thyroid stimulating hormone;GO:1904612//response to 2,3,7,8-tetrachlorodibenzodioxine;GO:1905217//response to astaxanthin;GO:1905225//response to thyrotropin-releasing hormone"	--
ENSG00000057608	89.572	84.573	83.927	75.722	75.176	73.946	4104	3926	2846	2589	2908	2496	GDI2	GDP dissociation inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:4227]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031982//vesicle;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005092//GDP-dissociation inhibitor activity;GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:1902018//negative regulation of cilium assembly;GO:1903565//negative regulation of protein localization to cilium	--
ENSG00000057657	0	0	0	0	0.012	0	0	0	0	0	1	0	PRDM1	PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001763//morphogenesis of a branching structure;GO:0001822//kidney development;GO:0001892//embryonic placenta development;GO:0001893//maternal placenta development;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0003170//heart valve development;GO:0003279//cardiac septum development;GO:0003281//ventricular septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032259//methylation;GO:0032823//regulation of natural killer cell differentiation;GO:0033082//regulation of extrathymic T cell differentiation;GO:0035904//aorta development;GO:0042127//regulation of cell population proliferation;GO:0042462//eye photoreceptor cell development;GO:0045087//innate immune response;GO:0045165//cell fate commitment;GO:0048844//artery morphogenesis;GO:0048869//cellular developmental process;GO:0051136//regulation of NK T cell differentiation;GO:0060576//intestinal epithelial cell development;GO:0060707//trophoblast giant cell differentiation;GO:0060976//coronary vasculature development;GO:1990654//sebum secreting cell proliferation	zf-C2H2
ENSG00000057663	8.777	7.245	8.945	7.828	6.624	8.084	522	425	378	337	347	354	ATG5	autophagy related 5 [Source:HGNC Symbol;Acc:HGNC:589]	Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Immune system;Transport and catabolism;Aging;Transport and catabolism;Immune system;Aging;Cell growth and death;Transport and catabolism	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04211//Longevity regulating pathway;ko04137//Mitophagy - animal;ko04622//RIG-I-like receptor signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04216//Ferroptosis;ko04136//Autophagy - other	K08339;K08339;K08339;K08339;K08339;K08339;K08339;K08339;K08339	GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005930//axoneme;GO:0016020//membrane;GO:0030424//axon;GO:0030670//phagocytic vesicle membrane;GO:0032991//protein-containing complex;GO:0034045//phagophore assembly site membrane;GO:0034274//Atg12-Atg5-Atg16 complex;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:1990234//transferase complex	GO:0005515//protein binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0001974//blood vessel remodeling;GO:0002376//immune system process;GO:0002718//regulation of cytokine production involved in immune response;GO:0006497//protein lipidation;GO:0006501//C-terminal protein lipidation;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0009410//response to xenobiotic stimulus;GO:0009620//response to fungus;GO:0010040//response to iron(II) ion;GO:0016236//macroautophagy;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0031397//negative regulation of protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0035973//aggrephagy;GO:0039689//negative stranded viral RNA replication;GO:0042311//vasodilation;GO:0043066//negative regulation of apoptotic process;GO:0043687//post-translational protein modification;GO:0044804//autophagy of nucleus;GO:0045060//negative thymic T cell selection;GO:0045824//negative regulation of innate immune response;GO:0048840//otolith development;GO:0050687//negative regulation of defense response to virus;GO:0050765//negative regulation of phagocytosis;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0055015//ventricular cardiac muscle cell development;GO:0060047//heart contraction;GO:0060548//negative regulation of cell death;GO:0061684//chaperone-mediated autophagy;GO:0061739//protein lipidation involved in autophagosome assembly;GO:0070257//positive regulation of mucus secretion;GO:0071500//cellular response to nitrosative stress;GO:1901096//regulation of autophagosome maturation;GO:1902017//regulation of cilium assembly;GO:1902617//response to fluoride;GO:1904973//positive regulation of viral translation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000619//negative regulation of histone H4-K16 acetylation	--
ENSG00000057704	7.318	7.77	6.09	6.705	7.25	6.33	794	851	496	547	669	500	TMCC3	transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0071889//14-3-3 protein binding	-	--
ENSG00000057757	14.259	16.088	13.88	16.366	13.521	18.253	467	527	335	395	372	438	PITHD1	PITH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25022]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0097598//sperm cytoplasmic droplet	-	"GO:0007286//spermatid development;GO:0007341//penetration of zona pellucida;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061136//regulation of proteasomal protein catabolic process;GO:0061956//penetration of cumulus oophorus"	--
ENSG00000057935	14.698	15.625	14.47	10.909	13.943	13.863	764	817	580	466	679	575	MTA3	metastasis associated 1 family member 3 [Source:HGNC Symbol;Acc:HGNC:23784]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016575//histone deacetylation;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000736//regulation of stem cell differentiation"	zf-GATA
ENSG00000058056	5.418	5.624	26.423	6.588	13.234	7.491	603	601.63	424.93	329.35	448	410	USP13	ubiquitin specific peptidase 13 [Source:HGNC Symbol;Acc:HGNC:12611]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0070628//proteasome binding;GO:1904288//BAT3 complex binding;GO:1990380//Lys48-specific deubiquitinase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0008283//cell population proliferation;GO:0010506//regulation of autophagy;GO:0016579//protein deubiquitination;GO:0030318//melanocyte differentiation;GO:0035523//protein K29-linked deubiquitination;GO:0044313//protein K6-linked deubiquitination;GO:0050821//protein stabilization;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1904294//positive regulation of ERAD pathway;GO:1904378//maintenance of unfolded protein involved in ERAD pathway"	--
ENSG00000058063	10.817	8.405	8.084	8.197	7.107	8.401	1117	864	636	604	722	689	ATP11B	ATPase phospholipid transporting 11B (putative) [Source:HGNC Symbol;Acc:HGNC:13553]	-	-	-	-	GO:0005637//nuclear inner membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0035577//azurophil granule membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015075//ion transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090555//phosphatidylethanolamine flippase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity	GO:0006811//ion transport;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0015917//aminophospholipid transport;GO:0034204//lipid translocation;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation	--
ENSG00000058085	2.025	2.244	1.272	1.595	2.1	1.978	218	251	104	128	195	154	LAMC2	laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06246;K06246;K06246;K06246;K06246;K06246;K06246;K06246	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005607//laminin-2 complex;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding	GO:0007155//cell adhesion;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0008544//epidermis development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016358//dendrite development;GO:0030335//positive regulation of cell migration	--
ENSG00000058091	1.389	1.667	1.318	1.347	1.269	1.73	149	152	95	107	115	135	CDK14	cyclin dependent kinase 14 [Source:HGNC Symbol;Acc:HGNC:8883]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K08821	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000308//cytoplasmic cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0106310//protein serine kinase activity	GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060828//regulation of canonical Wnt signaling pathway	--
ENSG00000058262	87.415	94.048	90.197	88.821	94.469	83.178	6447	6931.98	4865.99	4836.98	5883	4479	SEC61A1	SEC61 translocon subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:18276]	Cellular Processes;Genetic Information Processing;Human Diseases;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation;Infectious disease: bacterial;Folding, sorting and degradation"	ko04145//Phagosome;ko04141//Protein processing in endoplasmic reticulum;ko05110//Vibrio cholerae infection;ko03060//Protein export	K10956;K10956;K10956;K10956	GO:0005783//endoplasmic reticulum;GO:0005784//Sec61 translocon complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005048//signal sequence binding;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0043022//ribosome binding	"GO:0006613//cotranslational protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0031204//posttranslational protein targeting to membrane, translocation;GO:0039019//pronephric nephron development;GO:0045047//protein targeting to ER;GO:0045048//protein insertion into ER membrane;GO:0070588//calcium ion transmembrane transport"	--
ENSG00000058272	6.813	7.027	4.741	2.647	4.972	4.33	610	493	310	165	332	284	PPP1R12A	protein phosphatase 1 regulatory subunit 12A [Source:HGNC Symbol;Acc:HGNC:7618]	Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cancer: overview;Cellular community - eukaryotes;Signal transduction;Endocrine system;Circulatory system;Immune system	ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation	K06270;K06270;K06270;K06270;K06270;K06270;K06270;K06270	GO:0000776//kinetochore;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0031672//A band;GO:0043292//contractile fiber;GO:0072357//PTW/PP1 phosphatase complex	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity;GO:0019901//protein kinase binding;GO:0071889//14-3-3 protein binding	GO:0000278//mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0007098//centrosome cycle;GO:0007165//signal transduction;GO:0030155//regulation of cell adhesion;GO:0035507//regulation of myosin-light-chain-phosphatase activity;GO:0035508//positive regulation of myosin-light-chain-phosphatase activity;GO:0043086//negative regulation of catalytic activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046822//regulation of nucleocytoplasmic transport;GO:0050790//regulation of catalytic activity;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000058335	0.506	0.381	0.268	0.703	0.598	0.385	59	50	24	68	66	31	RASGRF1	Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875]	Environmental Information Processing;Environmental Information Processing;Cellular Processes	Signal transduction;Signal transduction;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04510//Focal adhesion	K04349;K04349;K04349	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030426//growth cone;GO:0043005//neuron projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0035254//glutamate receptor binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007616//long-term memory;GO:0008283//cell population proliferation;GO:0031175//neuron projection development;GO:0034976//response to endoplasmic reticulum stress;GO:0035020//regulation of Rac protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0046578//regulation of Ras protein signal transduction;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0090630//activation of GTPase activity;GO:2000310//regulation of NMDA receptor activity	--
ENSG00000058404	0.144	0.081	0.079	0.261	0.716	0.244	7	7	5	11	16	11	CAMK2B	calcium/calmodulin dependent protein kinase II beta [Source:HGNC Symbol;Acc:HGNC:1461]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Development and regeneration;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Circulatory system;Cell growth and death;Nervous system;Nervous system;Signal transduction;Nervous system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Endocrine system;Endocrine system;Endocrine system;Signal transduction;Cancer: specific types;Digestive system;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04217//Necroptosis;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko05214//Glioma;ko04971//Gastric acid secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0043005//neuron projection;GO:0043226//organelle;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development;GO:0014733//regulation of skeletal muscle adaptation;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0046777//protein autophosphorylation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0051823//regulation of synapse structural plasticity;GO:0051924//regulation of calcium ion transport;GO:0060998//regulation of dendritic spine development;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0090129//positive regulation of synapse maturation;GO:2001222//regulation of neuron migration	--
ENSG00000058453	3.546	3.471	3.705	2.873	3.819	3.102	484	482	378	294	385	278	CROCC	"ciliary rootlet coiled-coil, rootletin [Source:HGNC Symbol;Acc:HGNC:21299]"	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0015629//actin cytoskeleton;GO:0035253//ciliary rootlet;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0097729//9+2 motile cilium;GO:0120219//subapical part of cell	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0008104//protein localization;GO:0010457//centriole-centriole cohesion;GO:0010669//epithelial structure maintenance;GO:0030030//cell projection organization;GO:0032053//ciliary basal body organization;GO:0033365//protein localization to organelle;GO:0045494//photoreceptor cell maintenance;GO:0045724//positive regulation of cilium assembly;GO:0051656//establishment of organelle localization;GO:1903566//positive regulation of protein localization to cilium	--
ENSG00000058600	11.355	11.479	11.188	10.352	12.79	17.733	664	578	478	448	474	515	POLR3E	RNA polymerase III subunit E [Source:HGNC Symbol;Acc:HGNC:30347]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K14721;K14721	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0003899//DNA-directed 5'-3' RNA polymerase activity	"GO:0002376//immune system process;GO:0006351//transcription, DNA-templated;GO:0045087//innate immune response;GO:0051607//defense response to virus"	--
ENSG00000058668	19.193	19.097	18.41	15.286	17.633	17.923	3437	3426	2427	2044	2661	2354	ATP2B4	ATPase plasma membrane Ca2+ transporting 4 [Source:HGNC Symbol;Acc:HGNC:817]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Digestive system;Endocrine system;Digestive system;Digestive system;Excretory system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04972//Pancreatic secretion;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031514//motile cilium;GO:0032991//protein-containing complex;GO:0036126//sperm flagellum;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0097228//sperm principal piece;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0015085//calcium ion transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0017080//sodium channel regulator activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding;GO:0030346//protein phosphatase 2B binding;GO:0036487//nitric-oxide synthase inhibitor activity;GO:0046872//metal ion binding;GO:0050998//nitric-oxide synthase binding;GO:0097110//scaffold protein binding	GO:0003407//neural retina development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007283//spermatogenesis;GO:0010629//negative regulation of gene expression;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0014832//urinary bladder smooth muscle contraction;GO:0016525//negative regulation of angiogenesis;GO:0021766//hippocampus development;GO:0030317//flagellated sperm motility;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034220//ion transmembrane transport;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051599//response to hydrostatic pressure;GO:0070588//calcium ion transmembrane transport;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071872//cellular response to epinephrine stimulus;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098703//calcium ion import across plasma membrane;GO:0098736//negative regulation of the force of heart contraction;GO:0140199//negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process;GO:0150104//transport across blood-brain barrier;GO:1900082//negative regulation of arginine catabolic process;GO:1901660//calcium ion export;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1902305//regulation of sodium ion transmembrane transport;GO:1902548//negative regulation of cellular response to vascular endothelial growth factor stimulus;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:1903249//negative regulation of citrulline biosynthetic process;GO:1903779//regulation of cardiac conduction;GO:1905145//cellular response to acetylcholine;GO:2000481//positive regulation of cAMP-dependent protein kinase activity	--
ENSG00000058673	21.689	18.859	21.658	13.921	18.221	22.413	2304.38	2067.32	1720.61	1080.46	1823.28	1794.6	ZC3H11A	zinc finger CCCH-type containing 11A [Source:HGNC Symbol;Acc:HGNC:29093]	-	-	-	-	GO:0000346//transcription export complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000058729	4.785	4.144	5.133	3.957	4.489	3.617	388	330	257	210	289	202	RIOK2	RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K07179	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis;GO:0046777//protein autophosphorylation;GO:2000208//positive regulation of ribosomal small subunit export from nucleus;GO:2000234//positive regulation of rRNA processing	--
ENSG00000058799	18.875	20.018	18.226	16.486	16.512	17.626	678	717	476	432	494	458	YIPF1	Yip1 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:25231]	-	-	-	-	GO:0000138//Golgi trans cisterna;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031902//late endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0016192//vesicle-mediated transport	--
ENSG00000058804	13.101	11.127	10.067	9.051	10.606	9.855	1237	1056	702	633	846	677	NDC1	NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14315;K14315	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0070762//nuclear pore transmembrane ring	GO:0017056//structural constituent of nuclear pore;GO:0030674//protein-macromolecule adaptor activity	GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly;GO:0051664//nuclear pore localization	--
ENSG00000058866	0.093	0.084	0.09	0.146	0.079	0.089	7	6	8	13	8	7	DGKG	diacylglycerol kinase gamma [Source:HGNC Symbol;Acc:HGNC:2853]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0048666//neuron development;GO:0050773//regulation of dendrite development;GO:0090038//negative regulation of protein kinase C signaling	--
ENSG00000059122	35.272	32.694	41.852	51.044	49.767	45.458	2006	2170	1823	2220	2414	2035	FLYWCH1	FLYWCH-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:25404]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000059145	3.56	3.387	3.632	4.064	3.576	4.075	268.3	291.18	214.89	237.38	233.79	225.59	UNKL	unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000059377	0	0	0	0	0	0	0	0	0	0	0	0	TBXAS1	thromboxane A synthase 1 [Source:HGNC Symbol;Acc:HGNC:11609]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Immune system;Lipid metabolism	ko01100//Metabolic pathways;ko04611//Platelet activation;ko00590//Arachidonic acid metabolism	K01832;K01832;K01832	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004497//monooxygenase activity;GO:0004796//thromboxane-A synthase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0036134//12-hydroxyheptadecatrienoic acid synthase activity;GO:0046872//metal ion binding;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006690//icosanoid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0019371//cyclooxygenase pathway;GO:0030644//cellular chloride ion homeostasis;GO:0045471//response to ethanol;GO:0045907//positive regulation of vasoconstriction;GO:0070542//response to fatty acid	--
ENSG00000059378	15.944	14.084	15.039	14.912	15.044	17.212	975	886	696	683	796	765	PARP12	poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:1990404//protein ADP-ribosylase activity	GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation	Others
ENSG00000059573	25.73	29.612	27.731	26.35	25.131	24.39	1788	2069	1423	1356	1475	1233	ALDH18A1	aldehyde dehydrogenase 18 family member A1 [Source:HGNC Symbol;Acc:HGNC:9722]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism	K12657;K12657;K12657	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004349//glutamate 5-kinase activity;GO:0004350//glutamate-5-semialdehyde dehydrogenase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016740//transferase activity;GO:0042802//identical protein binding"	GO:0006536//glutamate metabolic process;GO:0006561//proline biosynthetic process;GO:0006592//ornithine biosynthetic process;GO:0008152//metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0016310//phosphorylation;GO:0019240//citrulline biosynthetic process;GO:0055129//L-proline biosynthetic process	--
ENSG00000059588	2.408	2.22	2.382	2.513	2.368	1.935	260	241	190	201	216	152	TARBP1	TAR (HIV-1) RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11568]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016423//tRNA (guanine) methyltransferase activity;GO:0016740//transferase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006396//RNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000059691	6.438	7.274	7.318	6.451	7.98	7.786	304	333	246	216	292	254	GATB	glutamyl-tRNA amidotransferase subunit B [Source:HGNC Symbol;Acc:HGNC:8849]	Metabolism;Genetic Information Processing	Global and overview maps;Translation	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis	K02434;K02434	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"	GO:0006412//translation;GO:0019752//carboxylic acid metabolic process;GO:0032543//mitochondrial translation;GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation	--
ENSG00000059728	2.428	2.009	2.348	1.876	2.237	2.684	280	225	200	160	218	225	MXD1	MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070443//Mad-Max complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	bHLH
ENSG00000059758	13.177	12.66	9.613	9.336	9.542	11.054	966	775	527	499	596	555	CDK17	cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000059769	4.075	4.282	3.948	3.03	3.672	4.262	197.83	210.15	140.25	109.82	152.23	151.35	DNAJC25	DnaJ heat shock protein family (Hsp40) member C25 [Source:HGNC Symbol;Acc:HGNC:34187]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006457//protein folding	--
ENSG00000059804	4.674	5.364	4.196	6.463	6.075	5.887	371	428	246	380	403	340	SLC2A3	solute carrier family 2 member 3 [Source:HGNC Symbol;Acc:HGNC:11007]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0005536//glucose binding;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0005975//carbohydrate metabolic process;GO:0008643//carbohydrate transport;GO:0015749//monosaccharide transmembrane transport;GO:0019852//L-ascorbic acid metabolic process;GO:0046323//glucose import;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:0098708//glucose import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1904659//glucose transmembrane transport	--
ENSG00000059915	2.68	2.518	3.56	4.265	4.093	5.447	88	88	79	113	99	118	PSD	pleckstrin and Sec7 domain containing [Source:HGNC Symbol;Acc:HGNC:9507]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12494	"GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0098999//extrinsic component of postsynaptic endosome membrane;GO:0099092//postsynaptic density, intracellular component"	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000060069	7.878	7.598	7.167	8.351	7.72	8.279	587	586	406	472	494	459	CTDP1	CTD phosphatase subunit 1 [Source:HGNC Symbol;Acc:HGNC:2498]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0051233//spindle midzone	GO:0001096//TFIIF-class transcription factor complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0030957//Tat protein binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0010458//exit from mitosis;GO:0043923//positive regulation by host of viral transcription;GO:0051301//cell division;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000060138	56.019	54.124	50.909	53.385	49.404	51.072	2164	2116	1457	1534	1638	1442	YBX3	Y-box binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2428]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06099	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0048471//perinuclear region of cytoplasm	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0043021//ribonucleoprotein complex binding;GO:1905538//polysome binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0009566//fertilization;GO:0010468//regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0046622//positive regulation of organ growth;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0060546//negative regulation of necroptotic process;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0071356//cellular response to tumor necrosis factor;GO:0071474//cellular hyperosmotic response;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:2000767//positive regulation of cytoplasmic translation	CSD
ENSG00000060140	0.087	0.052	0	0	0	0	5	3	0	0	0	0	STYK1	serine/threonine/tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18889]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0045087//innate immune response	--
ENSG00000060237	37.271	36.147	33.418	23.168	29.155	24.843	5458	5050	3551	2560	3397	2736	WNK1	WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:14540]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019869//chloride channel inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0030295//protein kinase activator activity;GO:0106310//protein serine kinase activity	GO:0002028//regulation of sodium ion transport;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006468//protein phosphorylation;GO:0006811//ion transport;GO:0007165//signal transduction;GO:0010766//negative regulation of sodium ion transport;GO:0010820//positive regulation of T cell chemotaxis;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032147//activation of protein kinase activity;GO:0033633//negative regulation of cell-cell adhesion mediated by integrin;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034260//negative regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0038116//chemokine (C-C motif) ligand 21 signaling pathway;GO:0048666//neuron development;GO:0050801//ion homeostasis;GO:0050852//T cell receptor signaling pathway;GO:0055080//cation homeostasis;GO:0090188//negative regulation of pancreatic juice secretion;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097022//lymphocyte migration into lymph node;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:1904062//regulation of cation transmembrane transport;GO:1990869//cellular response to chemokine;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000060339	8.45	8.125	6.523	4.55	6.168	6.1	618	559	366	274	408	356	CCAR1	cell division cycle and apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:24236]	-	-	-	-	GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0030335//positive regulation of cell migration;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000060491	15.846	16.876	18.871	21.282	18.601	17.031	822	869	714	820	822	645	OGFR	opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0140625//opioid growth factor receptor activity	GO:0001558//regulation of cell growth;GO:0040008//regulation of growth	--
ENSG00000060558	0.021	0	0	0	0	0	1	0	0	0	0	0	GNA15	G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: parasitic;Endocrine system;Infectious disease: parasitic	ko04020//Calcium signaling pathway;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko05142//Chagas disease	K04637;K04637;K04637;K04637	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001508//action potential;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007207//phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway	--
ENSG00000060566	0	0	0	0	0	0	0	0	0	0	0	0	CREB3L3	cAMP responsive element binding protein 3 like 3 [Source:HGNC Symbol;Acc:HGNC:18855]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity"	"GO:0002675//positive regulation of acute inflammatory response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006986//response to unfolded protein;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	TF_bZIP
ENSG00000060642	8.774	8.274	10.074	7.955	8.024	9.475	389	393	305	275	321	330	PIGV	phosphatidylinositol glycan anchor biosynthesis class V [Source:HGNC Symbol;Acc:HGNC:26031]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K07542;K07542	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031501//mannosyltransferase complex	"GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0004376//glycolipid mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0097502//mannosylation	--
ENSG00000060656	7.88	8.711	6.047	8.157	9.356	8.016	898	1011	509	698	913	669	PTPRU	protein tyrosine phosphatase receptor type U [Source:HGNC Symbol;Acc:HGNC:9683]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0016311//dephosphorylation;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0031100//animal organ regeneration;GO:0034109//homotypic cell-cell adhesion;GO:0034394//protein localization to cell surface;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051384//response to glucocorticoid;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin	--
ENSG00000060688	13.165	14.223	14.268	14.091	13.86	14.647	441	478	353	348	389	357	SNRNP40	small nuclear ribonucleoprotein U5 subunit 40 [Source:HGNC Symbol;Acc:HGNC:30857]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12857	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000060709	0.241	0.182	0.487	0.339	0.188	0.143	27	24	13	17	20	11	RIMBP2	RIMS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30339]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	GO:0007274//neuromuscular synaptic transmission	--
ENSG00000060718	24.606	22.996	17.799	18.987	19.363	20.344	3032	2748	1555	1555	1901	1695	COL11A1	collagen type XI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2186]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005592//collagen type XI trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding;GO:1904399//heparan sulfate binding	GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0002063//chondrocyte development;GO:0003007//heart morphogenesis;GO:0006029//proteoglycan metabolic process;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0035987//endodermal cell differentiation;GO:0035989//tendon development;GO:0042472//inner ear morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0051216//cartilage development;GO:0055010//ventricular cardiac muscle tissue morphogenesis	--
ENSG00000060749	9.95	6.117	6.688	4.207	5.175	5.825	1557	1097	759	598	803	751	QSER1	glutamine and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:26154]	-	-	-	-	GO:0005694//chromosome	-	-	--
ENSG00000060762	40.169	40.036	41.2	42.348	40.634	54.513	758	759	575	592	648	750	MPC1	mitochondrial pyruvate carrier 1 [Source:HGNC Symbol;Acc:HGNC:21606]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K22138	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0098800//inner mitochondrial membrane protein complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0050833//pyruvate transmembrane transporter activity	GO:0006850//mitochondrial pyruvate transmembrane transport;GO:0008150//biological_process	--
ENSG00000060971	30.221	29.555	30.88	32.746	31.396	29.878	1010.89	978.84	771.69	832.86	897	722	ACAA1	acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82]	Metabolism;Cellular Processes;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Endocrine system;Global and overview maps;Amino acid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko01040//Biosynthesis of unsaturated fatty acids;ko00592//alpha-Linolenic acid metabolism"	K07513;K07513;K07513;K07513;K07513;K07513;K07513;K07513	GO:0005576//extracellular region;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0035580//specific granule lumen	"GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0005515//protein binding;GO:0008775//acetate CoA-transferase activity;GO:0016401//palmitoyl-CoA oxidase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0050633//acetyl-CoA C-myristoyltransferase activity"	GO:0000038//very long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0008206//bile acid metabolic process;GO:0010124//phenylacetate catabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0036109//alpha-linolenic acid metabolic process	--
ENSG00000060982	105.863	84.22	73.951	34.712	49.263	53.015	13731	10280	6259	3135	4767	4122	BCAT1	branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins;Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00770//Pantothenate and CoA biosynthesis;ko01210//2-Oxocarboxylic acid metabolism;ko00290//Valine, leucine and isoleucine biosynthesis"	K00826;K00826;K00826;K00826;K00826;K00826;K00826	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004084//branched-chain-amino-acid transaminase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0050048//L-leucine:2-oxoglutarate aminotransferase activity;GO:0052654//L-leucine transaminase activity;GO:0052655//L-valine transaminase activity;GO:0052656//L-isoleucine transaminase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006629//lipid metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009081//branched-chain amino acid metabolic process;GO:0009082//branched-chain amino acid biosynthetic process;GO:0009098//leucine biosynthetic process;GO:0009099//valine biosynthetic process	--
ENSG00000061273	12.232	12.935	12.068	13.456	13.916	14.123	974	977	705	814	1008	785	HDAC7	histone deacetylase 7 [Source:HGNC Symbol;Acc:HGNC:14067]	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11408;K11408;K11408	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019789//SUMO transferase activity;GO:0019901//protein kinase binding;GO:0033558//protein deacetylase activity;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001570//vasculogenesis;GO:0006325//chromatin organization;GO:0006476//protein deacetylation;GO:0007043//cell-cell junction assembly;GO:0016575//histone deacetylation;GO:0016925//protein sumoylation;GO:0019222//regulation of metabolic process;GO:0032703//negative regulation of interleukin-2 production;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1901223//negative regulation of NIK/NF-kappaB signaling"	--
ENSG00000061337	0.237	0.228	0.263	0.468	0.45	0.381	28	26	22	39	44	32	LZTS1	leucine zipper tumor suppressor 1 [Source:HGNC Symbol;Acc:HGNC:13861]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0016242//negative regulation of macroautophagy;GO:0044772//mitotic cell cycle phase transition;GO:0048167//regulation of synaptic plasticity;GO:0048814//regulation of dendrite morphogenesis	--
ENSG00000061455	0.011	0.109	0.036	0.253	0.087	0.036	2	6	5	5	14	5	PRDM6	PR/SET domain 6 [Source:HGNC Symbol;Acc:HGNC:9350]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K20795;K20795	GO:0005634//nucleus	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0042054//histone methyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0010468//regulation of gene expression;GO:0016571//histone methylation;GO:0022008//neurogenesis;GO:0032259//methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051151//negative regulation of smooth muscle cell differentiation"	zf-C2H2
ENSG00000061492	0	0	0	0	0	0	0	0	0	0	0	0	WNT8A	Wnt family member 8A [Source:HGNC Symbol;Acc:HGNC:12788]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity	GO:0000902//cell morphogenesis;GO:0003002//regionalization;GO:0007275//multicellular organism development;GO:0007492//endoderm development;GO:0009948//anterior/posterior axis specification;GO:0009949//polarity specification of anterior/posterior axis;GO:0010085//polarity specification of proximal/distal axis;GO:0014034//neural crest cell fate commitment;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0032526//response to retinoic acid;GO:0032880//regulation of protein localization;GO:0044335//canonical Wnt signaling pathway involved in neural crest cell differentiation;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048561//establishment of animal organ orientation;GO:0060070//canonical Wnt signaling pathway;GO:0061317//canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:0062009//secondary palate development	--
ENSG00000061656	1.875	1.905	1.617	1.202	1.946	1.179	47	49	28	27	41	23	SPAG4	sperm associated antigen 4 [Source:HGNC Symbol;Acc:HGNC:11214]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0042995//cell projection	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0043495//protein-membrane adaptor activity	GO:0006998//nuclear envelope organization;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000061676	59.511	42.572	43.09	32.159	35.885	41.518	6389	4590	3419	2542	3243	3232	NCKAP1	NCK associated protein 1 [Source:HGNC Symbol;Acc:HGNC:7666]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04810//Regulation of actin cytoskeleton	K05750;K05750;K05750	GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0031258//lamellipodium membrane;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000902//cell morphogenesis;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0010592//positive regulation of lamellipodium assembly;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0030866//cortical actin cytoskeleton organization;GO:0048812//neuron projection morphogenesis;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000061794	21.649	23.318	23.353	23.521	19.536	21.293	794	848	654	627	609	586	MRPS35	mitochondrial ribosomal protein S35 [Source:HGNC Symbol;Acc:HGNC:16635]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0032543//mitochondrial translation	--
ENSG00000061918	0.954	1.191	0.548	0.661	0.785	0.471	62	68	26	25	41	20	GUCY1B1	guanylate cyclase 1 soluble subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4687]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Global and overview maps;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Immune system;Environmental adaptation;Digestive system;Cellular community - eukaryotes;Endocrine system;Nervous system	ko01100//Metabolic pathways;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04611//Platelet activation;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04540//Gap junction;ko04924//Renin secretion;ko04730//Long-term depression	K12319;K12319;K12319;K12319;K12319;K12319;K12319;K12319;K12319;K12319;K12319	"GO:0005737//cytoplasm;GO:0008074//guanylate cyclase complex, soluble;GO:0032991//protein-containing complex;GO:0048786//presynaptic active zone;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse"	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0004383//guanylate cyclase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0020037//heme binding;GO:0038023//signaling receptor activity;GO:0043167//ion binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047805//cytidylate cyclase activity;GO:0051879//Hsp90 protein binding	"GO:0006182//cGMP biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0008015//blood circulation;GO:0009190//cyclic nucleotide biosynthetic process;GO:0019934//cGMP-mediated signaling;GO:0035556//intracellular signal transduction;GO:0038060//nitric oxide-cGMP-mediated signaling pathway;GO:0071732//cellular response to nitric oxide;GO:0099555//trans-synaptic signaling by nitric oxide, modulating synaptic transmission"	--
ENSG00000061936	8.483	7.844	9.16	8.246	8.498	8.855	549	509	425	382	438	405	SFSWAP	splicing factor SWAP [Source:HGNC Symbol;Acc:HGNC:10790]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000061938	6.805	6.855	6.679	7.809	7.219	8.563	565	584	432	502	515	501	TNK2	tyrosine kinase non receptor 2 [Source:HGNC Symbol;Acc:HGNC:19297]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070436//Grb2-EGFR complex;GO:0097268//cytoophidium	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005095//GTPase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050699//WW domain binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000061987	6.689	6.224	6.213	4.516	4.831	5.43	889	828	605	435	570	560	MON2	"MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:HGNC Symbol;Acc:HGNC:29177]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006895//Golgi to endosome transport;GO:0015031//protein transport	--
ENSG00000062038	149.95	168.832	161.571	147.547	167.07	154.435	8068	8687	6517	5931	7256	5709	CDH3	cadherin 3 [Source:HGNC Symbol;Acc:HGNC:1762]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06796	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0030054//cell junction	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0001895//retina homeostasis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007601//visual perception;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0010838//positive regulation of keratinocyte proliferation;GO:0022405//hair cycle process;GO:0031424//keratinization;GO:0032773//positive regulation of tyrosinase activity;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0042060//wound healing;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048023//positive regulation of melanin biosynthetic process;GO:0050896//response to stimulus;GO:0051796//negative regulation of timing of catagen;GO:0060901//regulation of hair cycle by canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1902910//positive regulation of melanosome transport	--
ENSG00000062096	0.024	0	0	0.033	0	0	1	0	0	1	0	0	ARSF	arylsulfatase F [Source:HGNC Symbol;Acc:HGNC:721]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000062194	27.41	22.689	20.909	16.457	19.262	20.829	1688	1473	986	781	1002	923	GPBP1	GC-rich promoter binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29520]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	Others
ENSG00000062282	2.224	1.696	2.397	3.679	3.063	2.548	84	77	86	106	128	75	DGAT2	diacylglycerol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16940]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K11160;K11160;K11160	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:1990578//perinuclear endoplasmic reticulum membrane	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042803//protein homodimerization activity;GO:0050252//retinol O-fatty-acyltransferase activity	GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0006651//diacylglycerol biosynthetic process;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0019915//lipid storage;GO:0034383//low-density lipoprotein particle clearance;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0035356//cellular triglyceride homeostasis;GO:0038183//bile acid signaling pathway;GO:0042572//retinol metabolic process;GO:0042632//cholesterol homeostasis;GO:0044255//cellular lipid metabolic process;GO:0045722//positive regulation of gluconeogenesis;GO:0046322//negative regulation of fatty acid oxidation;GO:0046339//diacylglycerol metabolic process;GO:0050746//regulation of lipoprotein metabolic process;GO:0055089//fatty acid homeostasis;GO:0060613//fat pad development;GO:0071400//cellular response to oleic acid;GO:0090181//regulation of cholesterol metabolic process;GO:0097006//regulation of plasma lipoprotein particle levels	--
ENSG00000062370	2.921	2.521	1.974	2.199	1.522	2.179	184	127	108	121	92	116	ZNF112	zinc finger protein 112 [Source:HGNC Symbol;Acc:HGNC:12892]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000062485	75.882	78.126	80.244	91.17	80.715	82.063	4251.86	4391.67	3244.93	3746.92	3959.45	3307.14	CS	citrate synthase [Source:HGNC Symbol;Acc:HGNC:2422]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K01647;K01647;K01647;K01647;K01647;K01647	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0004108//citrate (Si)-synthase activity;GO:0016740//transferase activity;GO:0036440//citrate synthase activity;GO:0046912//acyltransferase, acyl groups converted into alkyl on transfer"	GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006101//citrate metabolic process	--
ENSG00000062524	0	0.026	0	0	0.039	0	0	1	0	0	2	0	LTK	leukocyte receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6721]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell population proliferation;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010976//positive regulation of neuron projection development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0071300//cellular response to retinoic acid	--
ENSG00000062582	30.189	27.74	34.685	42.889	32.868	29.77	421.49	390.41	360	447	388.69	304.47	MRPS24	mitochondrial ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:14510]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0008150//biological_process;GO:0032543//mitochondrial translation	--
ENSG00000062598	20.977	20.067	22.767	22.115	22.312	21.14	1437	1446	1174	1100	1274	1130	ELMO2	engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial	ko05132//Salmonella infection;ko05131//Shigellosis;ko05135//Yersinia infection;ko05100//Bacterial invasion of epithelial cells	K18985;K18985;K18985;K18985	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0030971//receptor tyrosine kinase binding	GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0048870//cell motility;GO:0060326//cell chemotaxis;GO:0098609//cell-cell adhesion	--
ENSG00000062650	8.259	6.514	6.435	5.698	5.987	6.602	1070	857	622	511	662	611	WAPL	WAPL cohesin release factor [Source:HGNC Symbol;Acc:HGNC:23293]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle"	GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007063//regulation of sister chromatid cohesion;GO:0008156//negative regulation of DNA replication;GO:0009636//response to toxic substance;GO:0035562//negative regulation of chromatin binding;GO:0045875//negative regulation of sister chromatid cohesion;GO:0048146//positive regulation of fibroblast proliferation;GO:0051301//cell division;GO:0051983//regulation of chromosome segregation;GO:0060623//regulation of chromosome condensation;GO:0071168//protein localization to chromatin;GO:0071922//regulation of cohesin loading	--
ENSG00000062716	28.502	31.46	30.685	27.631	26.222	25.156	1433	1638	1161	1011	1195	1009	VMP1	vacuole membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29559]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21248	GO:0000407//phagophore assembly site;GO:0000421//autophagosome membrane;GO:0005730//nucleolus;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity	GO:0000045//autophagosome assembly;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0007155//cell adhesion;GO:0007566//embryo implantation;GO:0016240//autophagosome membrane docking;GO:0017121//plasma membrane phospholipid scrambling;GO:0034329//cell junction assembly;GO:0042953//lipoprotein transport;GO:0098609//cell-cell adhesion;GO:0140056//organelle localization by membrane tethering;GO:1901896//positive regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000062725	15.664	14.807	13.605	12.833	11.199	16.236	1567	1428	1043	838	968	1123	APPBP2	amyloid beta precursor protein binding protein 2 [Source:HGNC Symbol;Acc:HGNC:622]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0046907//intracellular transport	--
ENSG00000062822	5.625	5.651	6.505	5.812	5.324	5.292	402	403	344	306	322	275	POLD1	"DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K02327;K02327;K02327;K02327;K02327	"GO:0000109//nucleotide-excision repair complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016235//aggresome;GO:0043625//delta DNA polymerase complex"	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0034644//cellular response to UV;GO:0044260//cellular macromolecule metabolic process;GO:0045004//DNA replication proofreading;GO:0055089//fatty acid homeostasis;GO:0070987//error-free translesion synthesis;GO:0071897//DNA biosynthetic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000063015	0.159	0.014	0.212	0.056	0.199	0.052	5	1	5	3	13	3	SEZ6	seizure related 6 homolog [Source:HGNC Symbol;Acc:HGNC:15955]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0048471//perinuclear region of cytoplasm;GO:0097440//apical dendrite	GO:0005515//protein binding	GO:0008344//adult locomotory behavior;GO:0021680//cerebellar Purkinje cell layer development;GO:0050773//regulation of dendrite development;GO:0060074//synapse maturation;GO:0060079//excitatory postsynaptic potential;GO:0090036//regulation of protein kinase C signaling	--
ENSG00000063046	226.02	230.747	217.223	215.761	200.74	219.091	14010	13927	9880	9746	10869	9797	EIF4B	eukaryotic translation initiation factor 4B [Source:HGNC Symbol;Acc:HGNC:3285]	Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Cancer: overview;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko05205//Proteoglycans in cancer;ko04150//mTOR signaling pathway	K03258;K03258;K03258	GO:0005829//cytosol;GO:0016281//eukaryotic translation initiation factor 4F complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0033592//RNA strand annealing activity;GO:0034057//RNA strand-exchange activity;GO:0043024//ribosomal small subunit binding	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0097010//eukaryotic translation initiation factor 4F complex assembly	--
ENSG00000063127	0.05	0.017	0.088	0.044	0.21	0.068	3	1	4	2	11	3	SLC6A16	solute carrier family 6 member 16 [Source:HGNC Symbol;Acc:HGNC:13622]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0015293//symporter activity	GO:0006836//neurotransmitter transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport	--
ENSG00000063169	1.712	1.636	1.584	2.129	2.117	1.771	202	194	138	186	211	152	BICRA	BRD4 interacting chromatin remodeling complex associated protein [Source:HGNC Symbol;Acc:HGNC:4332]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	GO:0005515//protein binding;GO:0140537//transcription regulator activator activity	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000063176	11.308	9.664	13.355	14.283	14.165	17.166	501.49	477.5	471.65	495.2	559.54	556.63	SPHK2	sphingosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:18859]	Metabolism;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Signal transduction;Immune system;Signal transduction;Signal transduction;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04371//Apelin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04370//VEGF signaling pathway;ko00600//Sphingolipid metabolism	K04718;K04718;K04718;K04718;K04718;K04718;K04718;K04718;K04718	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001727//lipid kinase activity;GO:0003951//NAD+ kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008481//sphinganine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017050//D-erythro-sphingosine kinase activity;GO:0031267//small GTPase binding;GO:0038036//sphingosine-1-phosphate receptor activity;GO:0042393//histone binding	"GO:0001568//blood vessel development;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006669//sphinganine-1-phosphate biosynthetic process;GO:0006670//sphingosine metabolic process;GO:0007420//brain development;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0031064//negative regulation of histone deacetylation;GO:0032736//positive regulation of interleukin-13 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033008//positive regulation of mast cell activation involved in immune response;GO:0043065//positive regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043306//positive regulation of mast cell degranulation;GO:0043977//histone H2A-K5 acetylation;GO:0043980//histone H2B-K12 acetylation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0046512//sphingosine biosynthetic process;GO:0046834//lipid phosphorylation;GO:0090037//positive regulation of protein kinase C signaling;GO:0090280//positive regulation of calcium ion import;GO:1901726//negative regulation of histone deacetylase activity;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:1904959//regulation of cytochrome-c oxidase activity;GO:2000304//positive regulation of ceramide biosynthetic process;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:2001169//regulation of ATP biosynthetic process"	--
ENSG00000063177	427.924	469.215	429.651	488.783	418.346	378.484	5707	6292	4237	4833	4716	3674	RPL18	ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02883;K02883	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0043232//intracellular non-membrane-bounded organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000063180	16.502	16.948	18.363	20.532	20.324	18.391	587	606	470	541	584	476	CA11	carbonic anhydrase 11 [Source:HGNC Symbol;Acc:HGNC:1370]	-	-	-	-	GO:0005576//extracellular region;GO:0016323//basolateral plasma membrane	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016836//hydro-lyase activity	GO:0006730//one-carbon metabolic process	--
ENSG00000063241	27.608	31.997	38.876	38.855	36.143	43.246	626	727	651	640	682	710	ISOC2	isochorismatase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26278]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0031648//protein destabilization	--
ENSG00000063244	60.906	61.827	71.703	73.202	64.843	64.657	2935	2980	2585	2565	2769	2477	U2AF2	U2 small nuclear RNA auxiliary factor 2 [Source:HGNC Symbol;Acc:HGNC:23156]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12837	GO:0000243//commitment complex;GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome;GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008187//poly-pyrimidine tract binding;GO:0019899//enzyme binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0070742//C2H2 zinc finger domain binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0031397//negative regulation of protein ubiquitination;GO:0033120//positive regulation of RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000063245	34.181	35.237	36.27	42.466	40.561	36.706	2084	2198	1659	1951	2117	1620	EPN1	epsin 1 [Source:HGNC Symbol;Acc:HGNC:21604]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12471	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030125//clathrin vesicle coat	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0030276//clathrin binding	GO:0001701//in utero embryonic development;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0007565//female pregnancy;GO:0048568//embryonic organ development;GO:1903671//negative regulation of sprouting angiogenesis	--
ENSG00000063322	20.334	20.935	21.716	20.941	19.192	19.609	1499	1556	1186	1147	1199	1055	MED29	mediator complex subunit 29 [Source:HGNC Symbol;Acc:HGNC:23074]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000063438	1.159	1.018	0.467	0.443	1.106	1.555	92.31	113	34.16	33.75	83	110	AHRR	aryl-hydrocarbon receptor repressor [Source:HGNC Symbol;Acc:HGNC:346]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0046983//protein dimerization activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006805//xenobiotic metabolic process;GO:0009410//response to xenobiotic stimulus"	bHLH
ENSG00000063515	0	0	0	0	0	0	0	0	0	0	0	0	GSC2	goosecoid homeobox 2 [Source:HGNC Symbol;Acc:HGNC:4613]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis"	Homeobox
ENSG00000063587	4.255	4.371	4.403	4.613	4.773	4.908	566	585	433	455	537	475	ZNF275	zinc finger protein 275 [Source:HGNC Symbol;Acc:HGNC:13069]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000063601	14.332	14.606	14.063	13.258	14.377	16.723	968	964	712	705	822	768	MTMR1	myotubularin related protein 1 [Source:HGNC Symbol;Acc:HGNC:7449]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18081;K18081;K18081	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042803//protein homodimerization activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0052866//phosphatidylinositol phosphate phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016311//dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0060304//regulation of phosphatidylinositol dephosphorylation	--
ENSG00000063660	63.695	65.084	64.049	60.361	64.963	61.379	4904	5017	3631	3449	4226	3445	GPC1	glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]	Human Diseases;Human Diseases	Cancer: overview;Cardiovascular disease	ko05205//Proteoglycans in cancer;ko05418//Fluid shear stress and atherosclerosis	K08107;K08107	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043202//lysosomal lumen;GO:0045121//membrane raft;GO:0045202//synapse;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0043236//laminin binding	GO:0001523//retinoid metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0009966//regulation of signal transduction;GO:0014037//Schwann cell differentiation;GO:0016477//cell migration;GO:0030200//heparan sulfate proteoglycan catabolic process;GO:0032288//myelin assembly;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:1905475//regulation of protein localization to membrane;GO:2001016//positive regulation of skeletal muscle cell differentiation	--
ENSG00000063761	7.656	7.261	8.535	11.624	11.319	9.035	263	244	213	283	313	205	ADCK1	aarF domain containing kinase 1 [Source:HGNC Symbol;Acc:HGNC:19038]	-	-	-	-	GO:0005576//extracellular region;GO:0005743//mitochondrial inner membrane;GO:0032592//integral component of mitochondrial membrane	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007005//mitochondrion organization;GO:0010637//negative regulation of mitochondrial fusion;GO:0016310//phosphorylation;GO:0055088//lipid homeostasis;GO:1903852//positive regulation of cristae formation	--
ENSG00000063854	28.607	29.784	32.822	33.436	32.424	33.331	718	769.05	632	640	675	634	HAGH	hydroxyacylglutathione hydrolase [Source:HGNC Symbol;Acc:HGNC:4805]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K01069;K01069	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0004416//hydroxyacylglutathione hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0019243//methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	--
ENSG00000063978	18.958	17.82	20.342	20.244	19.35	19.796	1124	1049	866	887	985	867	RNF4	ring finger protein 4 [Source:HGNC Symbol;Acc:HGNC:10067]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0016605//PML body;GO:1990752//microtubule end	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0030374//nuclear receptor coactivator activity;GO:0031491//nucleosome binding;GO:0032184//SUMO polymer binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046685//response to arsenic-containing substance;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination;GO:0090169//regulation of spindle assembly;GO:0090234//regulation of kinetochore assembly"	--
ENSG00000064012	2.172	2.39	1.341	1.64	1.487	1.189	96	95	49	51	67	43	CASP8	caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Immune system;Immune system;Drug resistance: antineoplastic;Cell growth and death;Immune system;Infectious disease: bacterial;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05416//Viral myocarditis;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398;K04398	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031264//death-inducing signaling complex;GO:0031265//CD95 death-inducing signaling complex;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045121//membrane raft;GO:0097342//ripoptosome	GO:0004197//cysteine-type endopeptidase activity;GO:0005123//death receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0035877//death effector domain binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0097110//scaffold protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0001525//angiogenesis;GO:0001817//regulation of cytokine production;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007507//heart development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0009409//response to cold;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0010941//regulation of cell death;GO:0030101//natural killer cell activation;GO:0030225//macrophage differentiation;GO:0032025//response to cobalt ion;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0032731//positive regulation of interleukin-1 beta production;GO:0034612//response to tumor necrosis factor;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045088//regulation of innate immune response;GO:0045471//response to ethanol;GO:0045651//positive regulation of macrophage differentiation;GO:0045862//positive regulation of proteolysis;GO:0046677//response to antibiotic;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0060546//negative regulation of necroptotic process;GO:0060715//syncytiotrophoblast cell differentiation involved in labyrinthine layer development;GO:0070269//pyroptosis;GO:0071260//cellular response to mechanical stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0097264//self proteolysis;GO:1901216//positive regulation of neuron death	--
ENSG00000064042	24.765	22.706	24.075	20.413	19.931	21.628	2706	2441	1835	1507	1816	1696	LIMCH1	LIM and calponin homology domains 1 [Source:HGNC Symbol;Acc:HGNC:29191]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016460//myosin II complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0032034//myosin II head/neck binding;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0030336//negative regulation of cell migration;GO:0031032//actomyosin structure organization;GO:0051496//positive regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0060327//cytoplasmic actin-based contraction involved in cell motility	--
ENSG00000064102	7.275	5.839	5.411	5.189	6.349	6.001	386	312	211	210	268	206	INTS13	integrator complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:20174]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0032039//integrator complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007346//regulation of mitotic cell cycle;GO:0030317//flagellated sperm motility;GO:0051301//cell division;GO:0051642//centrosome localization;GO:0080154//regulation of fertilization;GO:0090435//protein localization to nuclear envelope	--
ENSG00000064115	129.925	124.918	115.42	139.697	132.798	138.956	3816	3933	2763	3049	3361	2767	TM7SF3	transmembrane 7 superfamily member 3 [Source:HGNC Symbol;Acc:HGNC:23049]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0032024//positive regulation of insulin secretion;GO:0034620//cellular response to unfolded protein;GO:0043069//negative regulation of programmed cell death	--
ENSG00000064195	0.251	0.129	0.075	0.275	0.569	1.002	5	7	3	11	17	24	DLX3	distal-less homeobox 3 [Source:HGNC Symbol;Acc:HGNC:2916]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001568//blood vessel development;GO:0001890//placenta development;GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010467//gene expression;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0035315//hair cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042633//hair cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071335//hair follicle cell proliferation;GO:0071895//odontoblast differentiation"	Homeobox
ENSG00000064199	2.823	2.901	2.264	1.968	1.631	1.416	211	218	125	109	103	77	SPA17	sperm autoantigenic protein 17 [Source:HGNC Symbol;Acc:HGNC:11210]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0097228//sperm principal piece	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida	--
ENSG00000064201	1.42	1.982	1.619	0.814	0.567	0.757	33	49	32	17	13	12	TSPAN32	tetraspanin 32 [Source:HGNC Symbol;Acc:HGNC:13410]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070442//integrin alphaIIb-beta3 complex	GO:0003674//molecular_function	GO:0007010//cytoskeleton organization;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008285//negative regulation of cell population proliferation;GO:0030886//negative regulation of myeloid dendritic cell activation;GO:0042832//defense response to protozoan;GO:0050688//regulation of defense response to virus;GO:0051604//protein maturation;GO:0070527//platelet aggregation;GO:0072659//protein localization to plasma membrane	--
ENSG00000064205	0.038	0.211	0.153	0.081	0.223	0.216	1	6	3	2	5	5	CCN5	cellular communication network factor 5 [Source:HGNC Symbol;Acc:HGNC:12770]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0060548//negative regulation of cell death	--
ENSG00000064218	0	0	0.026	0.026	0.023	0	0	0	1	1	1	0	DMRT3	doublesex and mab-3 related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:13909]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007548//sex differentiation;GO:0007628//adult walking behavior;GO:0019226//transmission of nerve impulse;GO:0021521//ventral spinal cord interneuron specification;GO:0030154//cell differentiation;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0046661//male sex differentiation"	DM
ENSG00000064225	5.476	3.639	4.32	2.336	3.459	2.944	237	211	186	103	123	138	ST3GAL6	"ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K03792;K03792	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0052798//beta-galactoside alpha-2,3-sialyltransferase activity"	GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006664//glycolipid metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0018146//keratan sulfate biosynthetic process;GO:0071354//cellular response to interleukin-6;GO:0097503//sialylation	--
ENSG00000064270	0	0	0	0	0.034	0	0	0	0	0	2	0	ATP2C2	ATPase secretory pathway Ca2+ transporting 2 [Source:HGNC Symbol;Acc:HGNC:29103]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015662//P-type ion transporter activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140613//P-type manganese transporter activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0061180//mammary gland epithelium development;GO:0070588//calcium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0090280//positive regulation of calcium ion import	--
ENSG00000064300	0.014	0.028	0.081	0.191	0.435	0.194	1	2	4	10	26	10	NGFR	nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Signal transduction;Signaling molecules and interaction;Cancer: overview;Signal transduction;Signal transduction;Nervous system;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04722//Neurotrophin signaling pathway;ko04215//Apoptosis - multiple species	K02583;K02583;K02583;K02583;K02583;K02583;K02583;K02583	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0045202//synapse	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005035//death receptor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015026//coreceptor activity;GO:0031267//small GTPase binding;GO:0031625//ubiquitin protein ligase binding;GO:0038023//signaling receptor activity;GO:0043121//neurotrophin binding;GO:0048406//nerve growth factor binding	GO:0001678//cellular glucose homeostasis;GO:0006886//intracellular protein transport;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007623//circadian rhythm;GO:0010468//regulation of gene expression;GO:0016048//detection of temperature stimulus;GO:0021675//nerve development;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0031069//hair follicle morphogenesis;GO:0032922//circadian regulation of gene expression;GO:0035907//dorsal aorta development;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0042593//glucose homeostasis;GO:0043588//skin development;GO:0048146//positive regulation of fibroblast proliferation;GO:0048511//rhythmic process;GO:0051402//neuron apoptotic process;GO:0051799//negative regulation of hair follicle development;GO:1900182//positive regulation of protein localization to nucleus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1904646//cellular response to amyloid-beta;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000064309	4.54	5.709	5.339	4.829	6.343	5.891	643	788	540	508	710	607	CDON	"cell adhesion associated, oncogene regulated [Source:HGNC Symbol;Acc:HGNC:17104]"	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K20033	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	GO:0001708//cell fate specification;GO:0001934//positive regulation of protein phosphorylation;GO:0002088//lens development in camera-type eye;GO:0007155//cell adhesion;GO:0007224//smoothened signaling pathway;GO:0007399//nervous system development;GO:0007520//myoblast fusion;GO:0009952//anterior/posterior pattern specification;GO:0010172//embryonic body morphogenesis;GO:0014816//skeletal muscle satellite cell differentiation;GO:0021987//cerebral cortex development;GO:0043393//regulation of protein binding;GO:0043410//positive regulation of MAPK cascade;GO:0045663//positive regulation of myoblast differentiation;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048598//embryonic morphogenesis;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0051146//striated muscle cell differentiation;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0098609//cell-cell adhesion;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000064313	7.29	6.591	6.778	4.994	5.056	6.286	765	698	526	385	445	484	TAF2	TATA-box binding protein associated factor 2 [Source:HGNC Symbol;Acc:HGNC:11536]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03128	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex	GO:0000976//transcription cis-regulatory region binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006282//regulation of DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0014070//response to organic cyclic compound;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000064393	14.784	12.885	12.479	11.123	12.507	10.672	4145	3722	2687	2292	2935	2193	HIPK2	homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K08826	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0016605//PML body;GO:0090575//RNA polymerase II transcription regulator complex	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046332//SMAD binding;GO:0046790//virion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106310//protein serine kinase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001654//eye development;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007628//adult walking behavior;GO:0008284//positive regulation of cell population proliferation;GO:0008344//adult locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0010842//retina layer formation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030182//neuron differentiation;GO:0030218//erythrocyte differentiation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030578//PML body organization;GO:0032092//positive regulation of protein binding;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043388//positive regulation of DNA binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048596//embryonic camera-type eye morphogenesis;GO:0050882//voluntary musculoskeletal movement;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051726//regulation of cell cycle;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0060235//lens induction in camera-type eye;GO:0060395//SMAD protein signal transduction;GO:0061072//iris morphogenesis;GO:0071456//cellular response to hypoxia;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901796//regulation of signal transduction by p53 class mediator;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000064419	14.341	13.94	13.104	12.817	11.944	13.15	1278	1235	868	843	901	839	TNPO3	transportin 3 [Source:HGNC Symbol;Acc:HGNC:17103]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K15436	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005642//annulate lamellae;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0033036//macromolecule localization;GO:0071702//organic substance transport	--
ENSG00000064489	1.442	0.865	2.487	1.774	1.592	1.861	31.8	32.54	40.05	49.16	49.57	48.75	BORCS8-MEF2B	BORCS8-MEF2B readthrough [Source:HGNC Symbol;Acc:HGNC:39979]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04022//cGMP-PKG signaling pathway;ko04371//Apelin signaling pathway	K09261;K09261	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046983//protein dimerization activity"	"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development"	SRF
ENSG00000064490	18.324	20.923	18.68	19.997	19.653	20.427	393.73	468.8	299.87	326	373.45	321	RFXANK	regulatory factor X associated ankyrin containing protein [Source:HGNC Symbol;Acc:HGNC:9987]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune disease;Immune system	ko05152//Tuberculosis;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation	K08062;K08062;K08062	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007265//Ras protein signal transduction;GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000064545	18.52	16.59	19.113	24.976	22.54	20.557	494	582	497	521	569	525	TMEM161A	transmembrane protein 161A [Source:HGNC Symbol;Acc:HGNC:26020]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0032526//response to retinoic acid;GO:0034599//cellular response to oxidative stress;GO:0034644//cellular response to UV;GO:0045739//positive regulation of DNA repair;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	--
ENSG00000064547	6.528	7.923	8.392	8.86	8.82	8.859	244	270	198	231	259	216	LPAR2	lysophosphatidic acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:3168]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Cell motility;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway	K04291;K04291;K04291;K04291;K04291;K04291;K04291	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0070915//lysophosphatidic acid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019222//regulation of metabolic process	--
ENSG00000064601	96.029	103.711	109.321	133.099	112.66	115.847	3765.67	4078.8	3158.89	3867.14	3720.7	3310.34	CTSA	cathepsin A [Source:HGNC Symbol;Acc:HGNC:9251]	Cellular Processes;Organismal Systems	Transport and catabolism;Endocrine system	ko04142//Lysosome;ko04614//Renin-angiotensin system	K13289;K13289	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0098575//lumenal side of lysosomal membrane	GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006886//intracellular protein transport;GO:0031647//regulation of protein stability;GO:0050790//regulation of catalytic activity;GO:1904714//regulation of chaperone-mediated autophagy;GO:1904715//negative regulation of chaperone-mediated autophagy	--
ENSG00000064607	31.781	29.636	31.716	28.519	31.858	31.806	2901.44	2690	2164	2016	2554	2157	SUGP2	SURP and G-patch domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18641]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000064651	14.6	11.671	14.24	10.066	13.247	18.368	1785	1352	1248	910	1344	1566	SLC12A2	solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911]	Organismal Systems;Organismal Systems;Human Diseases	Digestive system;Digestive system;Infectious disease: bacterial	ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko05110//Vibrio cholerae infection	K10951;K10951;K10951	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031253//cell projection membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044297//cell body;GO:0044298//cell body membrane;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0089717//spanning component of membrane;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0008511//sodium:potassium:chloride symporter activity;GO:0008519//ammonium transmembrane transporter activity;GO:0015079//potassium ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006821//chloride transport;GO:0006883//cellular sodium ion homeostasis;GO:0006884//cell volume homeostasis;GO:0006972//hyperosmotic response;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007568//aging;GO:0010818//T cell chemotaxis;GO:0015698//inorganic anion transport;GO:0030007//cellular potassium ion homeostasis;GO:0030321//transepithelial chloride transport;GO:0030644//cellular chloride ion homeostasis;GO:0035633//maintenance of blood-brain barrier;GO:0035725//sodium ion transmembrane transport;GO:0035865//cellular response to potassium ion;GO:0045795//positive regulation of cell volume;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0055085//transmembrane transport;GO:0061044//negative regulation of vascular wound healing;GO:0070634//transepithelial ammonium transport;GO:0071805//potassium ion transmembrane transport;GO:0072488//ammonium transmembrane transport;GO:0098658//inorganic anion import across plasma membrane;GO:0098659//inorganic cation import across plasma membrane;GO:0098719//sodium ion import across plasma membrane;GO:0150003//regulation of spontaneous synaptic transmission;GO:0150104//transport across blood-brain barrier;GO:1902476//chloride transmembrane transport;GO:1904450//positive regulation of aspartate secretion;GO:1904464//regulation of matrix metallopeptidase secretion;GO:1990573//potassium ion import across plasma membrane;GO:1990869//cellular response to chemokine	--
ENSG00000064652	8.87	7.794	6.529	7.626	8.486	9.78	255	264	166	211	224	247	SNX24	sorting nexin 24 [Source:HGNC Symbol;Acc:HGNC:21533]	-	-	-	-	GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0015031//protein transport	--
ENSG00000064655	8.257	8.698	11.514	10.293	9.669	12.915	403	411	418	387	388	440	EYA2	EYA transcriptional coactivator and phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3520]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007275//multicellular organism development;GO:0007501//mesodermal cell fate specification;GO:0014706//striated muscle tissue development;GO:0016576//histone dephosphorylation;GO:0030154//cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045739//positive regulation of DNA repair;GO:0048856//anatomical structure development;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097345//mitochondrial outer membrane permeabilization;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000064666	104.6	116.401	104.567	137.02	131.815	124.133	4573	5093	3358	4447	4752	3965	CNN2	calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156]	-	-	-	-	GO:0001725//stress fiber;GO:0005576//extracellular region;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0045296//cadherin binding	GO:0007010//cytoskeleton organization;GO:0010628//positive regulation of gene expression;GO:0030097//hemopoiesis;GO:0030336//negative regulation of cell migration;GO:0031032//actomyosin structure organization;GO:0032970//regulation of actin filament-based process;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0050765//negative regulation of phagocytosis;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000064687	23.776	19.327	22.11	22.653	24.629	22.591	2717	2434	2241	2058	2511	2177	ABCA7	ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05645	GO:0000139//Golgi membrane;GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031901//early endosome membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097386//glial cell projection	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0005548//phospholipid transporter activity;GO:0016887//ATP hydrolysis activity;GO:0034188//apolipoprotein A-I receptor activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0090554//phosphatidylcholine floppase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140328//floppase activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0006909//phagocytosis;GO:0007613//memory;GO:0008542//visual learning;GO:0010875//positive regulation of cholesterol efflux;GO:0018149//peptide cross-linking;GO:0019216//regulation of lipid metabolic process;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034205//amyloid-beta formation;GO:0034380//high-density lipoprotein particle assembly;GO:0034504//protein localization to nucleus;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0043409//negative regulation of MAPK cascade;GO:0044857//plasma membrane raft organization;GO:0045332//phospholipid translocation;GO:0045806//negative regulation of endocytosis;GO:0050766//positive regulation of phagocytosis;GO:0055085//transmembrane transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1900223//positive regulation of amyloid-beta clearance;GO:1901076//positive regulation of engulfment of apoptotic cell;GO:1902430//negative regulation of amyloid-beta formation;GO:1902991//regulation of amyloid precursor protein catabolic process;GO:1902995//positive regulation of phospholipid efflux;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000064692	6.527	5.3	4.167	3.426	4.034	4.652	318	322	204	150	206	193	SNCAIP	synuclein alpha interacting protein [Source:HGNC Symbol;Acc:HGNC:11139]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K04558;K04558	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042734//presynaptic membrane;GO:0043025//neuronal cell body	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding	GO:0008219//cell death;GO:0042417//dopamine metabolic process;GO:0046928//regulation of neurotransmitter secretion;GO:0090083//regulation of inclusion body assembly	--
ENSG00000064703	6.885	6.909	6.317	5.155	5.604	6.09	427.45	433.54	298.99	236	303.44	282	DDX20	DEAD-box helicase 20 [Source:HGNC Symbol;Acc:HGNC:2743]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0017053//transcription repressor complex;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0090571//RNA polymerase II transcription repressor complex;GO:0097504//Gemini of coiled bodies	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048477//oogenesis;GO:0050810//regulation of steroid biosynthetic process"	--
ENSG00000064726	13.121	11.838	11.606	8.722	9.583	11.229	803	712	520	415	493	537	BTBD1	BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1120]	-	-	-	-	GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0097602//cullin family protein binding	GO:0007517//muscle organ development;GO:0016567//protein ubiquitination;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0043393//regulation of protein binding	--
ENSG00000064763	0.737	0.533	0.7	0.405	0.501	0.622	54	38	29	22	31	31	FAR2	fatty acyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:25531]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13356	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity;GO:0102965//alcohol-forming fatty acyl-CoA reductase activity"	GO:0006629//lipid metabolic process;GO:0010025//wax biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:1901568//fatty acid derivative metabolic process	--
ENSG00000064787	0.346	0.261	0.159	1.636	1.199	0.842	17	13	8	62	57	32	BCAS1	brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	-	GO:0042552//myelination	--
ENSG00000064835	0	0	0	0	0	0	0	0	0	0	0	0	POU1F1	POU class 1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9210]	Organismal Systems	Endocrine system	"ko04935//Growth hormone synthesis, secretion and action"	K09363	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106222//long noncoding RNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0021984//adenohypophysis development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Pou
ENSG00000064886	0.102	0.034	0.111	0.108	0.142	0.157	3	1	1	1	3	2	CHI3L2	chitinase 3 like 2 [Source:HGNC Symbol;Acc:HGNC:1933]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0008061//chitin binding;GO:0016787//hydrolase activity;GO:0030246//carbohydrate binding	GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process	--
ENSG00000064932	8.298	8.755	9.675	10.669	11.277	10.04	827	858	698	781	862	716	SBNO2	strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0031490//chromatin DNA binding;GO:0042393//histone binding	"GO:0001503//ossification;GO:0002281//macrophage activation involved in immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0030282//bone mineralization;GO:0030316//osteoclast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048583//regulation of response to stimulus;GO:0050727//regulation of inflammatory response;GO:0061430//bone trabecula morphogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0071348//cellular response to interleukin-11;GO:0071354//cellular response to interleukin-6;GO:0072674//multinuclear osteoclast differentiation;GO:0072675//osteoclast fusion;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000064933	5.465	3.596	3.795	3.297	3.225	4.38	290	216	151	135	150	165	PMS1	"PMS1 homolog 1, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9121]"	-	-	-	-	GO:0005634//nucleus;GO:0032300//mismatch repair complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0030983//mismatched DNA binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus	HMG
ENSG00000064961	37.681	36.752	39.988	42.851	36.93	39.354	1180	1149	936	954	974	896	HMG20B	high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0010468//regulation of gene expression;GO:0033234//negative regulation of protein sumoylation;GO:0035914//skeletal muscle cell differentiation;GO:0045666//positive regulation of neuron differentiation	HMG
ENSG00000064989	0.187	0.163	0.039	0.148	0.184	0.036	16	20	3	2	5	2	CALCRL	calcitonin receptor like receptor [Source:HGNC Symbol;Acc:HGNC:16709]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction	K04577;K04577	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1903143//adrenomedullin receptor complex;GO:1990406//CGRP receptor complex	GO:0001605//adrenomedullin receptor activity;GO:0001635//calcitonin gene-related peptide receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004948//calcitonin receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:1990409//adrenomedullin binding	"GO:0001525//angiogenesis;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0015031//protein transport;GO:0031623//receptor internalization;GO:0045986//negative regulation of smooth muscle contraction;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0071329//cellular response to sucrose stimulus;GO:1990408//calcitonin gene-related peptide receptor signaling pathway;GO:1990410//adrenomedullin receptor signaling pathway"	--
ENSG00000064995	13.232	11.621	12.93	11.745	10.758	10.335	502	444	357	318	341	282	TAF11	TATA-box binding protein associated factor 11 [Source:HGNC Symbol;Acc:HGNC:11544]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005794//Golgi apparatus	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043923//positive regulation by host of viral transcription;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000064999	7.191	7.607	7.652	7.715	7.278	7.555	903	926	733	655	725	677	ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A [Source:HGNC Symbol;Acc:HGNC:20961]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0006929//substrate-dependent cell migration;GO:0016322//neuron remodeling;GO:0048013//ephrin receptor signaling pathway;GO:1901187//regulation of ephrin receptor signaling pathway	--
ENSG00000065000	47.179	50.3	45.696	44.569	45.281	49.054	4664	5032	3477	3267	3897	3406	AP3D1	adaptor related protein complex 3 subunit delta 1 [Source:HGNC Symbol;Acc:HGNC:568]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12396	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030123//AP-3 adaptor complex;GO:0030424//axon;GO:0043195//terminal bouton;GO:0097708//intracellular vesicle;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098830//presynaptic endosome;GO:0098978//glutamatergic synapse;GO:1904115//axon cytoplasm	GO:0005515//protein binding	"GO:0006623//protein targeting to vacuole;GO:0006886//intracellular protein transport;GO:0006896//Golgi to vacuole transport;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016182//synaptic vesicle budding from endosome;GO:0016183//synaptic vesicle coating;GO:0016192//vesicle-mediated transport;GO:0019882//antigen processing and presentation;GO:0032438//melanosome organization;GO:0033365//protein localization to organelle;GO:0035646//endosome to melanosome transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0036465//synaptic vesicle recycling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046907//intracellular transport;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0048490//anterograde synaptic vesicle transport;GO:0048499//synaptic vesicle membrane organization;GO:0051138//positive regulation of NK T cell differentiation;GO:0060155//platelet dense granule organization;GO:0061088//regulation of sequestering of zinc ion;GO:0072657//protein localization to membrane;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0099003//vesicle-mediated transport in synapse;GO:1903232//melanosome assembly"	--
ENSG00000065029	11.324	9.991	12.136	12.954	12.869	12.632	555	509	446	461	526	465	ZNF76	zinc finger protein 76 [Source:HGNC Symbol;Acc:HGNC:13149]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006359//regulation of transcription by RNA polymerase III;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000065054	11.769	10.026	10.614	11.813	13.113	8.705	363	344	239	283	350	224	SLC9A3R2	SLC9A3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076]	Organismal Systems	Excretory system	ko04960//Aldosterone-regulated sodium reabsorption	K13358	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0019902//phosphatase binding;GO:0031799//type 2 metabotropic glutamate receptor binding;GO:0031800//type 3 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0043495//protein-membrane adaptor activity;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity	GO:0065003//protein-containing complex assembly;GO:0072659//protein localization to plasma membrane	--
ENSG00000065057	6.138	4.531	5.979	8.177	7.741	8.594	132	98	95	129	139	133	NTHL1	nth like DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:8028]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10773	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	"GO:0000703//oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008534//oxidized purine nucleobase lesion DNA N-glycosylase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016829//lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity"	"GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006285//base-excision repair, AP site formation;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006950//response to stress;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0045008//depyrimidination;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000065060	6.082	5.72	6.011	5.395	5.404	6.898	1207	1141	881	793	906	996	UHRF1BP1	UHRF1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21216]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding	-	--
ENSG00000065135	6.61	6.115	6.15	5.556	5.616	6.323	1240	1153	852	772	890	863	GNAI3	G protein subunit alpha i3 [Source:HGNC Symbol;Acc:HGNC:4387]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Immune system;Substance dependence;Development and regeneration;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Signal transduction;Endocrine system;Immune system;Nervous system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine system;Environmental adaptation;Endocrine system;Substance dependence;Cellular community - eukaryotes;Nervous system;Infectious disease: bacterial;Digestive system;Endocrine system;Endocrine system;Nervous system;Substance dependence	"ko05200//Pathways in cancer;ko05012//Parkinson disease;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko05133//Pertussis;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression;ko05030//Cocaine addiction"	K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005834//heterotrimeric G-protein complex;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0042588//zymogen granule;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0019003//GDP binding;GO:0019904//protein domain specific binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031821//G protein-coupled serotonin receptor binding;GO:0032794//GTPase activating protein binding;GO:0046872//metal ion binding	GO:0006906//vesicle fusion;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007212//dopamine receptor signaling pathway;GO:0007420//brain development;GO:0016239//positive regulation of macroautophagy;GO:0032930//positive regulation of superoxide anion generation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0046039//GTP metabolic process;GO:0051301//cell division;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000065150	55.492	49.373	45.447	43.283	46.643	44.446	4867	4338	2925	2770	3340	2838	IPO5	importin 5 [Source:HGNC Symbol;Acc:HGNC:6402]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K20222	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003723//RNA binding;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0031267//small GTPase binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0006610//ribosomal protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0042307//positive regulation of protein import into nucleus;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000065154	53.582	52.176	53.304	49.028	48.651	56.405	2265	2217	1665	1535	1737	1734	OAT	ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00819;K00819	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0004587//ornithine-oxo-acid transaminase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding;GO:0050155//ornithine(lysine) transaminase activity	GO:0007601//visual perception;GO:0010121//arginine catabolic process to proline via ornithine;GO:0019544//arginine catabolic process to glutamate;GO:0055129//L-proline biosynthetic process	--
ENSG00000065183	3.919	4.877	3.282	2.591	2.299	3.162	579	595.77	352	362	403	309	WDR3	WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12755]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14556	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031965//nuclear membrane;GO:0032040//small-subunit processome;GO:0034388//Pwp2p-containing subcomplex of 90S preribosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding	GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA	--
ENSG00000065243	10.134	7.229	7.281	5.544	7.397	7.16	1228	885	677	517	702	584	PKN2	protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]	Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: bacterial;Immune system	ko04151//PI3K-Akt signaling pathway;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway	K23691;K23691;K23691	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043296//apical junction complex;GO:0045111//intermediate filament cytoskeleton;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0042826//histone deacetylase binding;GO:0045296//cadherin binding;GO:0070063//RNA polymerase binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010631//epithelial cell migration;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030030//cell projection organization;GO:0032467//positive regulation of cytokinesis;GO:0035556//intracellular signal transduction;GO:0043297//apical junction assembly;GO:0045070//positive regulation of viral genome replication;GO:0045931//positive regulation of mitotic cell cycle;GO:0051301//cell division;GO:2000145//regulation of cell motility	--
ENSG00000065268	14.229	14.226	15.545	17.932	18.89	15.86	432	450	359	417	499	362	WDR18	WD repeat domain 18 [Source:HGNC Symbol;Acc:HGNC:17956]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005656//nuclear pre-replicative complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0097344//Rix1 complex;GO:0120293//dynein axonemal particle	GO:0005515//protein binding	GO:0006261//DNA-dependent DNA replication;GO:0006364//rRNA processing	--
ENSG00000065308	24.02	24.789	25.9	27.791	28.14	29.101	3511	3642	2796	3009	3475	3095	TRAM2	translocation associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:16855]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding	"GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0015031//protein transport;GO:0032964//collagen biosynthetic process;GO:0045048//protein insertion into ER membrane"	--
ENSG00000065320	0.314	0.545	0.174	0.272	0.439	0.199	39	68	16	25	46	18	NTN1	netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06843	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0005515//protein binding	"GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007097//nuclear migration;GO:0007265//Ras protein signal transduction;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016358//dendrite development;GO:0030334//regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0030879//mammary gland development;GO:0032488//Cdc42 protein signal transduction;GO:0033564//anterior/posterior axon guidance;GO:0042472//inner ear morphogenesis;GO:0045773//positive regulation of axon extension;GO:0051963//regulation of synapse assembly;GO:0060603//mammary gland duct morphogenesis;GO:0061643//chemorepulsion of axon;GO:0098609//cell-cell adhesion;GO:2000147//positive regulation of cell motility"	--
ENSG00000065325	0.023	0.034	0.016	0	0.144	0.07	2	3	1	0	5	2	GLP2R	glucagon like peptide 2 receptor [Source:HGNC Symbol;Acc:HGNC:4325]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04582	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004967//glucagon receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0071377//cellular response to glucagon stimulus	--
ENSG00000065328	0.181	0.218	0.292	0.124	0.312	0.431	14	19	15	6	6	4	MCM10	minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031298//replication fork protection complex	GO:0003677//DNA binding;GO:0003688//DNA replication origin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation	--
ENSG00000065357	3.362	3.309	4.068	3.274	2.995	2.768	133	155	103	81	87	96	DGKA	diacylglycerol kinase alpha [Source:HGNC Symbol;Acc:HGNC:2849]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0044255//cellular lipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation	--
ENSG00000065361	0.434	0.227	0.337	0.118	0.231	0.122	21	18	12	3	14	4	ERBB3	erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: overview;Signal transduction;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K05084;K05084;K05084;K05084;K05084;K05084;K05084	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0038143//ERBB3:ERBB2 complex;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0030296//protein tyrosine kinase activator activity;GO:0031625//ubiquitin protein ligase binding;GO:0038131//neuregulin receptor activity;GO:0038132//neuregulin binding;GO:0042802//identical protein binding;GO:0043125//ErbB-3 class receptor binding;GO:0046982//protein heterodimerization activity	GO:0003197//endocardial cushion development;GO:0006468//protein phosphorylation;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0009968//negative regulation of signal transduction;GO:0010628//positive regulation of gene expression;GO:0014037//Schwann cell differentiation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021545//cranial nerve development;GO:0033674//positive regulation of kinase activity;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0051048//negative regulation of secretion;GO:0051402//neuron apoptotic process;GO:0055025//positive regulation of cardiac muscle tissue development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000065371	0	0	0	0	0.115	0	0	0	0	0	2	0	ROPN1	rhophilin associated tail protein 1 [Source:HGNC Symbol;Acc:HGNC:17692]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001932//regulation of protein phosphorylation;GO:0030317//flagellated sperm motility;GO:0044782//cilium organization;GO:0048240//sperm capacitation;GO:0061512//protein localization to cilium	--
ENSG00000065413	0.797	0.881	0.36	0.609	0.554	0.521	98	73	35	44	50	41	ANKRD44	ankyrin repeat domain 44 [Source:HGNC Symbol;Acc:HGNC:25259]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000065427	44.979	47.868	41.214	39.582	43.065	42.266	1902	2013	1286	1248	1518	1270	KARS1	lysyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6215]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K04567	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003877//ATP adenylyltransferase activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004824//lysine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	"GO:0002276//basophil activation involved in immune response;GO:0002863//positive regulation of inflammatory response to antigenic stimulus;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006430//lysyl-tRNA aminoacylation;GO:0008033//tRNA processing;GO:0010165//response to X-ray;GO:0015966//diadenosine tetraphosphate biosynthetic process;GO:0043032//positive regulation of macrophage activation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070371//ERK1 and ERK2 cascade"	--
ENSG00000065457	5.668	6.997	6.246	8.242	7.73	6.828	522	563	406	367	431	350	ADAT1	adenosine deaminase tRNA specific 1 [Source:HGNC Symbol;Acc:HGNC:228]	-	-	-	-	-	GO:0003723//RNA binding;GO:0004000//adenosine deaminase activity;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006396//RNA processing;GO:0008033//tRNA processing	--
ENSG00000065485	14.999	15.488	17.31	14.154	14.309	13.927	562	595	489	401	461	387	PDIA5	protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane	GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity;GO:0016853//isomerase activity	GO:0006457//protein folding;GO:0022900//electron transport chain	--
ENSG00000065491	6.155	6.109	6.317	5.772	5.621	5.761	442	440.93	335	307	341	301	TBC1D22B	TBC1 domain family member 22B [Source:HGNC Symbol;Acc:HGNC:21602]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0071889//14-3-3 protein binding	GO:0090630//activation of GTPase activity	--
ENSG00000065518	65.482	68.855	72.995	75.612	62.886	73.188	895	941	735	762	731	725	NDUFB4	NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960;K03960	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006979//response to oxidative stress;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000065526	5.577	4.927	5.272	3.537	5.364	4.34	1302	1212	813	629	911	726	SPEN	spen family transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:17575]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050769//positive regulation of neurogenesis"	--
ENSG00000065534	28.608	26.862	20.807	24.266	29.21	27.789	3594	3350	1984	2406	3210	2542	MYLK	myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590]	Environmental Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cellular community - eukaryotes;Signal transduction;Endocrine system;Signal transduction;Circulatory system;Immune system;Digestive system	ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04971//Gastric acid secretion	K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0032154//cleavage furrow;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004687//myosin light chain kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006468//protein phosphorylation;GO:0006939//smooth muscle contraction;GO:0014820//tonic smooth muscle contraction;GO:0016310//phosphorylation;GO:0030335//positive regulation of cell migration;GO:0032060//bleb assembly;GO:0051928//positive regulation of calcium ion transport;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0071476//cellular hypotonic response;GO:0090303//positive regulation of wound healing	--
ENSG00000065548	19.546	16.476	18.278	14.158	15.107	19.304	816	698	564	442	535	592	ZC3H15	zinc finger CCCH-type containing 15 [Source:HGNC Symbol;Acc:HGNC:29528]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0002181//cytoplasmic translation;GO:0019221//cytokine-mediated signaling pathway;GO:0043547//positive regulation of GTPase activity	--
ENSG00000065559	13.32	13.515	14.826	12.2	14.504	14.905	1014	937	726	657	767	743	MAP2K4	mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6844]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cardiovascular disease;Immune system;Endocrine system;Endocrine system;Signal transduction;Infectious disease: parasitic;Immune system;Endocrine system;Signal transduction;Infectious disease: bacterial	"ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05132//Salmonella infection;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05161//Hepatitis B;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04926//Relaxin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04912//GnRH signaling pathway;ko04012//ErbB signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection"	K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430;K04430	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008545//JUN kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0009611//response to wounding;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0090398//cellular senescence;GO:2000672//negative regulation of motor neuron apoptotic process	--
ENSG00000065600	5.291	5.183	5.285	3.391	4.2	4.477	269	249	199	125	175	161	PACC1	proton activated chloride channel 1 [Source:HGNC Symbol;Acc:HGNC:25593]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0061797//pH-gated chloride channel activity	GO:0006811//ion transport;GO:0006821//chloride transport	--
ENSG00000065609	4.511	4.011	4.565	4.594	5.871	6.624	177	171	155	155	214	178	SNAP91	synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986]	-	-	-	-	GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0098894//extrinsic component of presynaptic endocytic zone membrane	"GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005545//1-phosphatidylinositol binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019901//protein kinase binding;GO:0030276//clathrin binding;GO:0032050//clathrin heavy chain binding"	GO:0006900//vesicle budding from membrane;GO:0015031//protein transport;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0048268//clathrin coat assembly;GO:0072583//clathrin-dependent endocytosis;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000065613	10.881	7.103	7.17	4.378	5.9	6.072	1737	1140	844	517	798	706	SLK	STE20 like kinase [Source:HGNC Symbol;Acc:HGNC:11088]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K08836	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031252//cell leading edge;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0016310//phosphorylation;GO:0030334//regulation of cell migration;GO:0031122//cytoplasmic microtubule organization;GO:0042981//regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0051893//regulation of focal adhesion assembly	--
ENSG00000065615	1.514	0.794	0.652	1.495	0.583	1.086	141	124	92	106	94	81	CYB5R4	cytochrome b5 reductase 4 [Source:HGNC Symbol;Acc:HGNC:20147]	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0003032//detection of oxygen;GO:0006091//generation of precursor metabolites and energy;GO:0006801//superoxide metabolic process;GO:0015701//bicarbonate transport;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis;GO:0046677//response to antibiotic;GO:0048468//cell development;GO:0072593//reactive oxygen species metabolic process	--
ENSG00000065618	0.374	0.234	0.318	0.079	0.139	0.202	15	8	8	2	4	5	COL17A1	collagen type XVII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2194]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K07603	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007160//cell-matrix adhesion;GO:0008544//epidermis development;GO:0030198//extracellular matrix organization;GO:0031581//hemidesmosome assembly	--
ENSG00000065621	1.182	0.91	1.408	1.543	1.09	1.824	108	86	86	81	88	102	GSTO2	glutathione S-transferase omega 2 [Source:HGNC Symbol;Acc:HGNC:23064]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0050610//methylarsonate reductase activity	GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019852//L-ascorbic acid metabolic process;GO:0071243//cellular response to arsenic-containing substance;GO:0098869//cellular oxidant detoxification	--
ENSG00000065665	3.25	3.9	4.389	4.022	4.214	3.345	139	166	145	130	162	111	SEC61A2	SEC61 translocon subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:17702]	Cellular Processes;Genetic Information Processing;Human Diseases;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation;Infectious disease: bacterial;Folding, sorting and degradation"	ko04145//Phagosome;ko04141//Protein processing in endoplasmic reticulum;ko05110//Vibrio cholerae infection;ko03060//Protein export	K10956;K10956;K10956;K10956	GO:0005783//endoplasmic reticulum;GO:0005784//Sec61 translocon complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0043022//ribosome binding	"GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0008150//biological_process;GO:0015031//protein transport;GO:0031204//posttranslational protein targeting to membrane, translocation"	--
ENSG00000065675	15.719	14.95	17.809	14.429	16.15	16.169	1058	1013	884	718	918	793	PRKCQ	protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410]	Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Signal transduction;Transport and catabolism;Circulatory system;Endocrine and metabolic disease;Immune system;Immune system;Sensory system;Immune system;Cancer: overview;Endocrine system	ko05131//Shigellosis;ko04064//NF-kappa B signaling pathway;ko04140//Autophagy - animal;ko04270//Vascular smooth muscle contraction;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04920//Adipocytokine signaling pathway	K18052;K18052;K18052;K18052;K18052;K18052;K18052;K18052;K18052;K18052;K18052	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016235//aggresome;GO:0034451//centriolar satellite	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0001558//regulation of cell growth;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006509//membrane protein ectodomain proteolysis;GO:0006954//inflammatory response;GO:0007411//axon guidance;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032740//positive regulation of interleukin-17 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051973//positive regulation of telomerase activity;GO:0060326//cell chemotaxis;GO:0070233//negative regulation of T cell apoptotic process;GO:0090330//regulation of platelet aggregation;GO:1904355//positive regulation of telomere capping;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000570//positive regulation of T-helper 2 cell activation"	--
ENSG00000065717	2.512	2.31	2.796	3.382	2.744	5.025	125	123	111	137	124	157	TLE2	"TLE family member 2, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11838]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005925//focal adhesion;GO:0016604//nuclear body	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0009887//animal organ morphogenesis;GO:0016055//Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000065802	5.6	6.624	7.512	6.259	6.372	7.79	783	776	659	571	661	639	ASB1	ankyrin repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:16011]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0001818//negative regulation of cytokine production;GO:0016567//protein ubiquitination;GO:0030539//male genitalia development;GO:0035556//intracellular signal transduction	--
ENSG00000065809	5.482	5.772	4.828	6.057	8.279	8.694	319	294	209	276	304	288	FAM107B	family with sequence similarity 107 member B [Source:HGNC Symbol;Acc:HGNC:23726]	-	-	-	-	-	-	-	--
ENSG00000065833	4.564	3.319	2.777	3.588	4.308	4.605	316	231	142	184	252	232	ME1	malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983]	Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Global and overview maps;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko03320//PPAR signaling pathway;ko00620//Pyruvate metabolism	K00029;K00029;K00029;K00029	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004470//malic enzyme activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0008948//oxaloacetate decarboxylase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0050661//NADP binding;GO:0051287//NAD binding	GO:0005975//carbohydrate metabolic process;GO:0006090//pyruvate metabolic process;GO:0006108//malate metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0009725//response to hormone;GO:0009743//response to carbohydrate;GO:0022900//electron transport chain;GO:1902031//regulation of NADP metabolic process	--
ENSG00000065882	116.856	104.179	116.641	98.095	98.984	113.209	7152	6390	5225	4522	5168	5027	TBC1D1	TBC1 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:11578]	Environmental Information Processing	Signal transduction	ko04152//AMPK signaling pathway	K18341	GO:0005634//nucleus	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0032880//regulation of protein localization;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000065883	11.988	10.207	10.265	9.018	9.361	10.814	1249	1056	773	674	833	842	CDK13	cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0002945//cyclin K-CDK13 complex;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0016607//nuclear speck;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030332//cyclin binding;GO:0106310//protein serine kinase activity	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0007088//regulation of mitotic nuclear division;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0030097//hemopoiesis;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051301//cell division;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:2000737//negative regulation of stem cell differentiation"	--
ENSG00000065911	12.174	9.707	10.078	10.001	7.319	32.952	506.59	416.49	298.37	284.73	272.56	1004.12	MTHFD2	"methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K13403;K13403	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity;GO:0042301//phosphate ion binding	GO:0006730//one-carbon metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0008152//metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0046653//tetrahydrofolate metabolic process;GO:0046655//folic acid metabolic process	--
ENSG00000065923	2.582	2.545	2.646	1.828	2.284	1.821	534	529	402	280	399	274	SLC9A7	solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123]	Organismal Systems	Circulatory system	ko04260//Cardiac muscle contraction	K12041	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport;GO:1905526//regulation of Golgi lumen acidification	--
ENSG00000065970	6.232	5.983	6.31	6.952	6.663	7.173	714	689	534	590	645	598	FOXJ2	forkhead box J2 [Source:HGNC Symbol;Acc:HGNC:24818]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051321//meiotic cell cycle;GO:0110059//negative regulation of blood vessel endothelial cell differentiation;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation"	Fork_head
ENSG00000065978	338.318	332.962	331.392	341.68	312.669	317.28	11918	11830	8606	8860	9252	8212	YBX1	Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005689//U12-type spliceosomal complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010494//cytoplasmic stress granule;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0070937//CRD-mediated mRNA stability complex;GO:0071204//histone pre-mRNA 3'end processing complex;GO:1990124//messenger ribonucleoprotein complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0051020//GTPase binding;GO:0062153//C5-methylcytidine-containing RNA binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0008544//epidermis development;GO:0010468//regulation of gene expression;GO:0017148//negative regulation of translation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048255//mRNA stabilization;GO:0048598//embryonic morphogenesis;GO:0050658//RNA transport;GO:0051031//tRNA transport;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0051781//positive regulation of cell division;GO:0070934//CRD-mediated mRNA stabilization;GO:0098761//cellular response to interleukin-7;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1903608//protein localization to cytoplasmic stress granule;GO:1990428//miRNA transport;GO:2000767//positive regulation of cytoplasmic translation;GO:2000773//negative regulation of cellular senescence"	CSD
ENSG00000065989	1.727	1.473	1.343	1.422	1.255	1.877	139	124	76	75	92	103	PDE4A	phosphodiesterase 4A [Source:HGNC Symbol;Acc:HGNC:8780]	Metabolism;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction"	K13293;K13293;K13293;K13293;K13293	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030552//cAMP binding;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0010738//regulation of protein kinase A signaling;GO:0071466//cellular response to xenobiotic stimulus;GO:0106070//regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000066027	37.722	34.484	39.448	43.464	41.537	51.314	2539	2333	1961	2167	2362	2513	PPP2R5A	protein phosphatase 2 regulatory subunit B'alpha [Source:HGNC Symbol;Acc:HGNC:9309]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11584;K11584;K11584;K11584;K11584;K11584;K11584;K11584	"GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030018//Z disc;GO:0031430//M band"	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0019900//kinase binding;GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0035307//positive regulation of protein dephosphorylation;GO:0090219//negative regulation of lipid kinase activity;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000066032	0.327	0.584	0.639	0.388	0.268	0.261	26	23	31	20	18	14	CTNNA2	catenin alpha 2 [Source:HGNC Symbol;Acc:HGNC:2510]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types;Immune system;Infectious disease: bacterial;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types	ko05200//Pathways in cancer;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05213//Endometrial cancer	K05691;K05691;K05691;K05691;K05691;K05691;K05691;K05691	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016342//catenin complex;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0016477//cell migration;GO:0021942//radial glia guided migration of Purkinje cell;GO:0030154//cell differentiation;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0048813//dendrite morphogenesis;GO:0048854//brain morphogenesis;GO:0051823//regulation of synapse structural plasticity;GO:0060134//prepulse inhibition;GO:0090136//epithelial cell-cell adhesion;GO:0098609//cell-cell adhesion;GO:2001222//regulation of neuron migration	--
ENSG00000066044	42.644	44.115	47.292	42.709	43.489	43.318	2042	2021	1638	1505	1673	1508	ELAVL1	ELAV like RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3312]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04152//AMPK signaling pathway;ko04657//IL-17 signaling pathway	K13088;K13088	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035198//miRNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0042803//protein homodimerization activity	GO:0006606//protein import into nucleus;GO:0016441//posttranscriptional gene silencing;GO:0045727//positive regulation of translation;GO:0048255//mRNA stabilization;GO:0051260//protein homooligomerization;GO:0060965//negative regulation of gene silencing by miRNA;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:2000036//regulation of stem cell population maintenance	--
ENSG00000066056	0	0	0	0	0.029	0	0	0	0	0	2	0	TIE1	tyrosine kinase with immunoglobulin like and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:11809]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001936//regulation of endothelial cell proliferation;GO:0003180//aortic valve morphogenesis;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007498//mesoderm development;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030336//negative regulation of cell migration;GO:0032526//response to retinoic acid;GO:0033674//positive regulation of kinase activity;GO:0045026//plasma membrane fusion;GO:0045766//positive regulation of angiogenesis;GO:0048771//tissue remodeling;GO:0060836//lymphatic endothelial cell differentiation;GO:0060854//branching involved in lymph vessel morphogenesis;GO:1901201//regulation of extracellular matrix assembly	--
ENSG00000066084	17.042	16.304	17.06	13.69	15.058	14.813	3077	2959	2275	1831	2297	1946	DIP2B	disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0043014//alpha-tubulin binding	GO:0007399//nervous system development;GO:0008150//biological_process;GO:0030517//negative regulation of axon extension;GO:2000758//positive regulation of peptidyl-lysine acetylation	--
ENSG00000066117	18.767	21.641	22.883	23.821	25.494	23.96	1034	1090	893	865	1090	904	SMARCD1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [Source:HGNC Symbol;Acc:HGNC:11106]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11650;K11650	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0035060//brahma complex;GO:0043231//intracellular membrane-bounded organelle;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140288//GBAF complex	GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	"GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:0071398//cellular response to fatty acid;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000066135	18.802	21.527	18.963	19.262	19.099	22.564	1645	1807.74	1198	1249.68	1404	1312	KDM4A	lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0031625//ubiquitin protein ligase binding;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140681//histone H3-tri/dimethyl-lysine-36 demethylase activity;GO:0140684//histone H3-tri/dimethyl-lysine-9 demethylase activity	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0010507//negative regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0016577//histone demethylation;GO:0031667//response to nutrient levels;GO:0033169//histone H3-K9 demethylation;GO:0045666//positive regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048712//negative regulation of astrocyte differentiation;GO:0060548//negative regulation of cell death;GO:0070544//histone H3-K36 demethylation;GO:1900113//negative regulation of histone H3-K9 trimethylation"	--
ENSG00000066136	31.486	32.522	33.797	32.284	35.185	42.269	1084	1085	864	879	1041	1049	NFYC	nuclear transcription factor Y subunit gamma [Source:HGNC Symbol;Acc:HGNC:7806]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05152//Tuberculosis;ko04612//Antigen processing and presentation	K08066;K08066	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006457//protein folding;GO:0035065//regulation of histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0080182//histone H3-K4 trimethylation"	NF-YC
ENSG00000066185	0.902	1.504	0.928	0.51	0.41	1.484	15	26	17	12	11	11	ZMYND12	zinc finger MYND-type containing 12 [Source:HGNC Symbol;Acc:HGNC:21192]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000066230	4.316	4.009	3.91	4.231	4.142	4.593	463.36	432.6	310.98	338.34	375.66	358.78	SLC9A3	solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Digestive system;Excretory system	ko04974//Protein digestion and absorption;ko04976//Bile secretion;ko04978//Mineral absorption;ko04964//Proximal tubule bicarbonate reclamation	K12040;K12040;K12040;K12040	GO:0005886//plasma membrane;GO:0005903//brush border;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity;GO:0030165//PDZ domain binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000066248	0.172	0.045	0.021	0.028	0.134	0.116	3	3	1	1	6	4	NGEF	neuronal guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:7807]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07525	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030426//growth cone;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0043087//regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0090630//activation of GTPase activity	--
ENSG00000066279	0.426	0.3	0.114	0.076	0.137	0.152	88	68	16	11	25	25	ASPM	assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016324//apical plasma membrane;GO:0030496//midbody;GO:0036449//microtubule minus-end;GO:0072687//meiotic spindle;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0001764//neuron migration;GO:0002052//positive regulation of neuroblast proliferation;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008584//male gonad development;GO:0021873//forebrain neuroblast division;GO:0021987//cerebral cortex development;GO:0045665//negative regulation of neuron differentiation;GO:0045769//negative regulation of asymmetric cell division;GO:0048477//oogenesis;GO:0048589//developmental growth;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0051653//spindle localization;GO:0051661//maintenance of centrosome location;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090306//meiotic spindle assembly;GO:0097150//neuronal stem cell population maintenance	--
ENSG00000066294	0	0	0	0	0.014	0	0	0	0	0	2	0	CD84	CD84 molecule [Source:HGNC Symbol;Acc:HGNC:1704]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006914//autophagy;GO:0006952//defense response;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0032685//negative regulation of granulocyte macrophage colony-stimulating factor production;GO:0032701//negative regulation of interleukin-18 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033004//negative regulation of mast cell activation;GO:0042110//T cell activation;GO:0043030//regulation of macrophage activation;GO:0043305//negative regulation of mast cell degranulation;GO:0045087//innate immune response;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000066322	36.942	42.067	45.812	52.139	52.337	54.859	1126	1289	1031	1177	1350	1218	ELOVL1	ELOVL fatty acid elongase 1 [Source:HGNC Symbol;Acc:HGNC:14418]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10247;K10247;K10247;K10247	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0061436//establishment of skin barrier"	--
ENSG00000066336	0	0.145	0	0.197	0.147	0.057	0	2	0	2	3	1	SPI1	Spi-1 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:11241]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Infectious disease: viral;Development and regeneration;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko04380//Osteoclast differentiation;ko05221//Acute myeloid leukemia	K09438;K09438;K09438;K09438;K09438	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001216//DNA-binding transcription activator activity;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0051525//NFAT protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097677//STAT family protein binding;GO:0140297//DNA-binding transcription factor binding;GO:0140311//protein sequestering activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001944//vasculature development;GO:0002314//germinal center B cell differentiation;GO:0002316//follicular B cell differentiation;GO:0002320//lymphoid progenitor cell differentiation;GO:0002327//immature B cell differentiation;GO:0002357//defense response to tumor cell;GO:0002572//pro-T cell differentiation;GO:0002573//myeloid leukocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030098//lymphocyte differentiation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030225//macrophage differentiation;GO:0030851//granulocyte differentiation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0035019//somatic stem cell population maintenance;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0043011//myeloid dendritic cell differentiation;GO:0043314//negative regulation of neutrophil degranulation;GO:0043966//histone H3 acetylation;GO:0044027//hypermethylation of CpG island;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0045646//regulation of erythrocyte differentiation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0060033//anatomical structure regression;GO:0070102//interleukin-6-mediated signaling pathway;GO:0090241//negative regulation of histone H4 acetylation;GO:0090402//oncogene-induced cell senescence;GO:0098508//endothelial to hematopoietic transition;GO:0120186//negative regulation of protein localization to chromatin;GO:1900745//positive regulation of p38MAPK cascade;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901674//regulation of histone H3-K27 acetylation;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904151//positive regulation of microglial cell mediated cytotoxicity;GO:1904178//negative regulation of adipose tissue development;GO:1904238//pericyte cell differentiation;GO:1905036//positive regulation of antifungal innate immune response;GO:1905453//regulation of myeloid progenitor cell differentiation;GO:2000529//positive regulation of myeloid dendritic cell chemotaxis"	ETS
ENSG00000066379	8.153	6.391	5.92	9.639	7.39	7.273	135	108	72	118	103	89	POLR1H	RNA polymerase I subunit H [Source:HGNC Symbol;Acc:HGNC:13182]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K03000	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex	GO:0003676//nucleic acid binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006139//nucleobase-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0006363//termination of RNA polymerase I transcription;GO:0006379//mRNA cleavage"	--
ENSG00000066382	1.928	1.674	1.891	2.52	2.212	1.785	97	86	70	97	97	67	MPPED2	metallophosphoesterase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:1180]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016208//AMP binding;GO:0016787//hydrolase activity;GO:0019002//GMP binding;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	-	--
ENSG00000066405	0.024	0.071	0	0.078	0.056	0	1	3	0	4	2	0	CLDN18	claudin 18 [Source:HGNC Symbol;Acc:HGNC:2039]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045471//response to ethanol;GO:0045779//negative regulation of bone resorption;GO:0048565//digestive tract development;GO:0070830//bicellular tight junction assembly;GO:0071847//TNFSF11-mediated signaling pathway;GO:1900181//negative regulation of protein localization to nucleus;GO:2001205//negative regulation of osteoclast development	--
ENSG00000066422	5.388	4.251	3.959	2.911	3.742	3.545	583	442	305	225	340	271	ZBTB11	zinc finger and BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:16740]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	ZBTB
ENSG00000066427	4.241	2.906	2.715	3.049	3.884	4.562	155	134	100	108	129	142	ATXN3	ataxin 3 [Source:HGNC Symbol;Acc:HGNC:7106]	Human Diseases;Genetic Information Processing;Human Diseases	"Neurodegenerative disease;Folding, sorting and degradation;Neurodegenerative disease"	ko05022//Pathways of neurodegeneration - multiple diseases;ko04141//Protein processing in endoplasmic reticulum;ko05017//Spinocerebellar ataxia	K11863;K11863;K11863	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0031966//mitochondrial membrane;GO:0042405//nuclear inclusion body;GO:0045202//synapse	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0051117//ATPase binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006289//nucleotide-excision repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0010810//regulation of cell-substrate adhesion;GO:0016579//protein deubiquitination;GO:0019538//protein metabolic process;GO:0030036//actin cytoskeleton organization;GO:0034605//cellular response to heat;GO:0035520//monoubiquitinated protein deubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045104//intermediate filament cytoskeleton organization;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071218//cellular response to misfolded protein;GO:1904294//positive regulation of ERAD pathway;GO:1904379//protein localization to cytosolic proteasome complex involved in ERAD pathway	--
ENSG00000066455	12.003	9.663	9.617	6.081	6.422	7.263	689	580	413	269	324	290	GOLGA5	golgin A5 [Source:HGNC Symbol;Acc:HGNC:4428]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031985//Golgi cisterna	GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0007030//Golgi organization;GO:0048193//Golgi vesicle transport"	--
ENSG00000066468	52.382	53.22	50.244	43.748	46.324	48.241	4176	4232	2871	2533	3105	2806	FGFR2	fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Transport and catabolism;Signal transduction;Cell motility;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05215//Prostate cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05230//Central carbon metabolism in cancer	K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093;K05093	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex;GO:0060076//excitatory synapse;GO:0062023//collagen-containing extracellular matrix	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001657//ureteric bud development;GO:0001701//in utero embryonic development;GO:0001837//epithelial to mesenchymal transition;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003148//outflow tract septum morphogenesis;GO:0003149//membranous septum morphogenesis;GO:0003416//endochondral bone growth;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling;GO:0007409//axonogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008589//regulation of smoothened signaling pathway;GO:0009791//post-embryonic development;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0010518//positive regulation of phospholipase activity;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016310//phosphorylation;GO:0016331//morphogenesis of embryonic epithelium;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021769//orbitofrontal cortex development;GO:0021847//ventricular zone neuroblast division;GO:0021860//pyramidal neuron development;GO:0022612//gland morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030282//bone mineralization;GO:0030324//lung development;GO:0030855//epithelial cell differentiation;GO:0030901//midbrain development;GO:0030916//otic vesicle formation;GO:0031069//hair follicle morphogenesis;GO:0032496//response to lipopolysaccharide;GO:0032808//lacrimal gland development;GO:0033674//positive regulation of kinase activity;GO:0033688//regulation of osteoblast proliferation;GO:0035265//organ growth;GO:0035602//fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell;GO:0035603//fibroblast growth factor receptor signaling pathway involved in hemopoiesis;GO:0035604//fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow;GO:0035607//fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development;GO:0042060//wound healing;GO:0042472//inner ear morphogenesis;GO:0042476//odontogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045165//cell fate commitment;GO:0045471//response to ethanol;GO:0045667//regulation of osteoblast differentiation;GO:0045787//positive regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0048286//lung alveolus development;GO:0048333//mesodermal cell differentiation;GO:0048513//animal organ development;GO:0048557//embryonic digestive tract morphogenesis;GO:0048562//embryonic organ morphogenesis;GO:0048565//digestive tract development;GO:0048568//embryonic organ development;GO:0048608//reproductive structure development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048730//epidermis morphogenesis;GO:0048755//branching morphogenesis of a nerve;GO:0048762//mesenchymal cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051150//regulation of smooth muscle cell differentiation;GO:0051781//positive regulation of cell division;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060174//limb bud formation;GO:0060348//bone development;GO:0060349//bone morphogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060449//bud elongation involved in lung branching;GO:0060463//lung lobe morphogenesis;GO:0060484//lung-associated mesenchyme development;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0060512//prostate gland morphogenesis;GO:0060523//prostate epithelial cord elongation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060529//squamous basal epithelial stem cell differentiation involved in prostate gland acinus development;GO:0060595//fibroblast growth factor receptor signaling pathway involved in mammary gland specification;GO:0060601//lateral sprouting from an epithelium;GO:0060615//mammary gland bud formation;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060667//branch elongation involved in salivary gland morphogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060688//regulation of morphogenesis of a branching structure;GO:0060915//mesenchymal cell differentiation involved in lung development;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071300//cellular response to retinoic acid;GO:0071363//cellular response to growth factor stimulus;GO:0071495//cellular response to endogenous stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000066557	4.748	3.256	3.834	3.091	2.67	3.776	280	193	167	135	133	162	LRRC40	leucine rich repeat containing 40 [Source:HGNC Symbol;Acc:HGNC:26004]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000066583	13.281	12.374	14.782	13.272	12.812	16.714	529	501	422	396	436	480	ISOC1	isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254]	-	-	-	-	GO:0005737//cytoplasm;GO:0005777//peroxisome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000066629	10.211	10.51	9.65	7.459	8.565	7.593	863	863	633	457	510	473	EML1	EMAP like 1 [Source:HGNC Symbol;Acc:HGNC:3330]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole;GO:1990023//mitotic spindle midzone	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007052//mitotic spindle organization;GO:0007405//neuroblast proliferation;GO:0007420//brain development	--
ENSG00000066651	3.508	2.805	2.693	2.452	3.458	2.176	118	103	78	67	105	64	TRMT11	tRNA methyltransferase 11 homolog [Source:HGNC Symbol;Acc:HGNC:21080]	-	-	-	-	GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000066654	12.307	11.399	9.696	7.225	8.23	8.694	1081	1008	630	475	618	561	THUMPD1	THUMP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23807]	-	-	-	-	GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006400//tRNA modification	--
ENSG00000066697	16.504	14.989	15.71	12.983	13.662	17.364	512	441	364	314	295	357	MSANTD3	Myb/SANT DNA binding domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23370]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000066735	2.603	2.284	2.539	3.445	3.603	3.722	371	328	268	362	435	380	KIF26A	kinesin family member 26A [Source:HGNC Symbol;Acc:HGNC:20226]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding	GO:0001560//regulation of cell growth by extracellular stimulus;GO:0007018//microtubule-based movement;GO:0009968//negative regulation of signal transduction;GO:0048484//enteric nervous system development	--
ENSG00000066739	4.828	4.322	3.982	3.466	4.106	4.395	1318	1186	803	701	947	873	ATG2B	autophagy related 2B [Source:HGNC Symbol;Acc:HGNC:20187]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04136//Autophagy - other	K17906;K17906;K17906;K17906;K17906;K17906;K17906	GO:0000407//phagophore assembly site;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0034045//phagophore assembly site membrane	GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0120013//lipid transfer activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0034727//piecemeal microautophagy of the nucleus;GO:0044805//late nucleophagy;GO:0061709//reticulophagy;GO:0120009//intermembrane lipid transfer	--
ENSG00000066777	12.332	9.195	7.761	5.117	6.957	7.543	1708	1192	836	574	827	765	ARFGEF1	ADP ribosylation factor guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:15772]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18442	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030532//small nuclear ribonucleoprotein complex;GO:0048471//perinuclear region of cytoplasm;GO:0098791//Golgi apparatus subcompartment	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0034237//protein kinase A regulatory subunit binding	GO:0006887//exocytosis;GO:0007030//Golgi organization;GO:0010256//endomembrane system organization;GO:0015031//protein transport;GO:0030837//negative regulation of actin filament polymerization;GO:0032012//regulation of ARF protein signal transduction;GO:0034260//negative regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0090284//positive regulation of protein glycosylation in Golgi;GO:0090303//positive regulation of wound healing;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000066813	0	0	0	0	0	0	0	0	0	0	0	0	ACSM2B	acyl-CoA synthetase medium chain family member 2B [Source:HGNC Symbol;Acc:HGNC:30931]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015645//fatty acid ligase activity;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0018858//benzoate-CoA ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0102391//decanoate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000066827	3.508	4.047	4.348	3.491	3.443	3.75	325	383	307	247	278	260	ZFAT	zinc finger and AT-hook domain containing [Source:HGNC Symbol;Acc:HGNC:19899]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0002244//hematopoietic progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030097//hemopoiesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060712//spongiotrophoblast layer development"	zf-C2H2
ENSG00000066855	7.317	7.573	7.418	5.18	5.435	6.149	355	355	279	211	241	218	MTFR1	mitochondrial fission regulator 1 [Source:HGNC Symbol;Acc:HGNC:29510]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0000266//mitochondrial fission;GO:0007005//mitochondrion organization;GO:0009060//aerobic respiration	--
ENSG00000066923	0.763	1.103	0.953	0.526	0.611	0.683	51	63	48	26	34	33	STAG3	stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K13055	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0000802//transverse filament;GO:0001673//male germ cell nucleus;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0008278//cohesin complex;GO:0030893//meiotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex"	GO:0003682//chromatin binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0034502//protein localization to chromosome;GO:0051321//meiotic cell cycle	--
ENSG00000066926	11.953	13.15	12.239	14.386	14.481	13.303	592	643	445	483	543	469	FECH	ferrochelatase [Source:HGNC Symbol;Acc:HGNC:3647]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01772;K01772	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	"GO:0004325//ferrochelatase activity;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016829//lyase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006091//generation of precursor metabolites and energy;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006783//heme biosynthetic process;GO:0009416//response to light stimulus;GO:0046501//protoporphyrinogen IX metabolic process	--
ENSG00000066933	3.48	2.254	1.993	1.762	2.003	1.926	635	420	278	199	346	265	MYO9A	myosin IXA [Source:HGNC Symbol;Acc:HGNC:7608]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016459//myosin complex;GO:0016461//unconventional myosin complex;GO:0030054//cell junction;GO:0030426//growth cone;GO:0042995//cell projection;GO:0044295//axonal growth cone;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0034329//cell junction assembly;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0150011//regulation of neuron projection arborization	--
ENSG00000067048	25.25	25.13	26.975	19.27	21.142	24.162	1981	1797	1495	1088	1346	1348	DDX3Y	DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043186//P granule	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007276//gamete generation;GO:0030154//cell differentiation	--
ENSG00000067057	41.073	44.851	41.596	46.669	47.437	36.821	2240	2460	1678	1889	2185	1463	PFKP	"phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878]"	Metabolism;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Metabolism;Organismal Systems;Genetic Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	"Global and overview maps;Endocrine system;Signal transduction;Signal transduction;Global and overview maps;Endocrine system;Folding, sorting and degradation;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00030//Pentose phosphate pathway	K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005945//6-phosphofructokinase complex;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003872//6-phosphofructokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0048029//monosaccharide binding;GO:0070095//fructose-6-phosphate binding	"GO:0006002//fructose 6-phosphate metabolic process;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0061615//glycolytic process through fructose-6-phosphate;GO:0061621//canonical glycolysis;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000067064	24.532	21.693	23.996	27.105	23.111	27.336	1302	1149	942	1074	1040	1063	IDI1	isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387]	Metabolism;Metabolism	Global and overview maps;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko00900//Terpenoid backbone biosynthesis	K01823;K01823	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0004452//isopentenyl-diphosphate delta-isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0009240//isopentenyl diphosphate biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0050992//dimethylallyl diphosphate biosynthetic process	--
ENSG00000067066	14.082	12.848	13.244	10.264	8.504	10.285	541	540	343	260	299	290	SP100	SP100 nuclear antigen [Source:HGNC Symbol;Acc:HGNC:11206]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05168//Herpes simplex virus 1 infection;ko05203//Viral carcinogenesis	K15413;K15413	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0016605//PML body;GO:0030870//Mre11 complex;GO:0034399//nuclear periphery"	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070087//chromo shadow domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000723//telomere maintenance;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0010596//negative regulation of endothelial cell migration;GO:0032526//response to retinoic acid;GO:0032897//negative regulation of viral transcription;GO:0034097//response to cytokine;GO:0034340//response to type I interferon;GO:0034341//response to interferon-gamma;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045185//maintenance of protein location;GO:0045765//regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046826//negative regulation of protein export from nucleus;GO:0048384//retinoic acid receptor signaling pathway;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051271//negative regulation of cellular component movement;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902044//regulation of Fas signaling pathway"	SAND
ENSG00000067082	4.839	3.952	4.574	3.688	3.667	4.251	447	367	312	259	294	289	KLF6	Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0030183//B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000067113	12.914	14.672	16.042	11.453	10.985	11.966	413.12	471.93	379.02	267.28	296.95	278.58	PLPP1	phospholipid phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:9228]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Immune system;Cancer: overview;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism;ko04975//Fat digestion and absorption	K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000810//diacylglycerol diphosphate phosphatase activity;GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0106235//ceramide-1-phosphate phosphatase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0006672//ceramide metabolic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0016311//dephosphorylation;GO:0019216//regulation of lipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0044238//primary metabolic process;GO:0046839//phospholipid dephosphorylation;GO:0071704//organic substance metabolic process	--
ENSG00000067141	48.486	50.502	50.877	59.753	62.564	64.69	5446	5734	4295	5109	6010	5290	NEO1	neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754]	Organismal Systems;Environmental Information Processing;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction;Signal transduction	ko04360//Axon guidance;ko04514//Cell adhesion molecules;ko04350//TGF-beta signaling pathway	K06766;K06766;K06766	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044295//axonal growth cone;GO:0098797//plasma membrane protein complex	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0039706//co-receptor binding	GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030513//positive regulation of BMP signaling pathway;GO:0055072//iron ion homeostasis;GO:0098609//cell-cell adhesion	--
ENSG00000067167	110.248	97.483	101.059	89.693	86.919	102.46	6991	6214	4737	4217	4656	4726	TRAM1	translocation associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:20568]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14010	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	"GO:0006613//cotranslational protein targeting to membrane;GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0006986//response to unfolded protein;GO:0015031//protein transport;GO:0045048//protein insertion into ER membrane"	--
ENSG00000067177	9.306	9.009	8.257	6.825	8.046	8.317	1125	1075	718	575	800	739	PHKA1	phosphorylase kinase regulatory subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8925]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04910//Insulin signaling pathway;ko04922//Glucagon signaling pathway	K07190;K07190;K07190	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005964//phosphorylase kinase complex;GO:0016020//membrane	GO:0004689//phosphorylase kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation	--
ENSG00000067182	64.875	67.775	73.041	68.947	73.373	74.282	2784	2953	2251	2165	2602	2209	TNFRSF1A	TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes	Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Development and regeneration;Signal transduction;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Infectious disease: parasitic;Signaling molecules and interaction;Endocrine system;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04071//Sphingolipid signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04920//Adipocytokine signaling pathway;ko04215//Apoptosis - multiple species	K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158;K03158	GO:0000139//Golgi membrane;GO:0002947//tumor necrosis factor receptor superfamily complex;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0110165//cellular anatomical entity	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0043120//tumor necrosis factor binding	GO:0003176//aortic valve development;GO:0003177//pulmonary valve development;GO:0003332//negative regulation of extracellular matrix constituent secretion;GO:0006693//prostaglandin metabolic process;GO:0006915//apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0071260//cellular response to mechanical stimulus;GO:0072659//protein localization to plasma membrane;GO:1902339//positive regulation of apoptotic process involved in morphogenesis;GO:1903140//regulation of establishment of endothelial barrier	--
ENSG00000067191	1.045	0.842	0.737	0.761	0.704	0.944	77	57	42	37	42	53	CACNB1	calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04862;K04862;K04862;K04862;K04862;K04862;K04862	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0042383//sarcolemma;GO:0045202//synapse;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0034765//regulation of ion transmembrane transport;GO:0045933//positive regulation of muscle contraction;GO:0070588//calcium ion transmembrane transport;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:1904646//cellular response to amyloid-beta	--
ENSG00000067208	1.941	2.427	2.205	0.62	1.37	2.336	305	208	161	72	170	155	EVI5	ecotropic viral integration site 5 [Source:HGNC Symbol;Acc:HGNC:3501]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0007049//cell cycle;GO:0042147//retrograde transport, endosome to Golgi;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0051301//cell division;GO:0090630//activation of GTPase activity"	--
ENSG00000067221	6.38	6.769	7.961	8.153	7.252	6.393	267	254	202	214	221	191	STOML1	stomatin like 1 [Source:HGNC Symbol;Acc:HGNC:14560]	-	-	-	-	GO:0005575//cellular_component;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0045121//membrane raft	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006869//lipid transport;GO:0008150//biological_process	--
ENSG00000067225	734.767	796.77	724.24	754.809	766.607	636.204	33677	36620	24237	25352	29409	20888	PKM	pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]	Metabolism;Human Diseases;Human Diseases;Metabolism;Organismal Systems;Metabolism;Human Diseases;Metabolism;Human Diseases;Metabolism	Global and overview maps;Infectious disease: viral;Cancer: overview;Global and overview maps;Endocrine system;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Endocrine and metabolic disease;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko04930//Type II diabetes mellitus;ko00620//Pyruvate metabolism	K00873;K00873;K00873;K00873;K00873;K00873;K00873;K00873;K00873;K00873	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005929//cilium;GO:0031982//vesicle;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003824//catalytic activity;GO:0004743//pyruvate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0023026//MHC class II protein complex binding;GO:0030955//potassium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006096//glycolytic process;GO:0006417//regulation of translation;GO:0008152//metabolic process;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0032869//cellular response to insulin stimulus;GO:1903672//positive regulation of sprouting angiogenesis;GO:2000767//positive regulation of cytoplasmic translation	--
ENSG00000067248	18.038	14.398	11.561	7.857	8.198	8.268	1745	1400	826	563	670	582	DHX29	DExH-box helicase 29 [Source:HGNC Symbol;Acc:HGNC:15815]	-	-	-	-	GO:0005737//cytoplasm;GO:0016282//eukaryotic 43S preinitiation complex;GO:0022627//cytosolic small ribosomal subunit	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003743//translation initiation factor activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0008494//translation activator activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0017111//nucleoside-triphosphatase activity;GO:0043024//ribosomal small subunit binding;GO:0045296//cadherin binding"	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0042255//ribosome assembly;GO:0045948//positive regulation of translational initiation	--
ENSG00000067334	6.871	6.338	6.248	4.089	4.649	3.678	424	377	264	191	241	167	DNTTIP2	deoxynucleotidyltransferase terminal interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:24013]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006396//RNA processing	--
ENSG00000067365	3.608	3.501	4.495	5.718	3.394	4.35	140	140	118	121	106	96	METTL22	"methyltransferase 22, Kin17 lysine [Source:HGNC Symbol;Acc:HGNC:28368]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0032259//methylation	--
ENSG00000067369	18.118	19.306	16.445	11.608	13.783	14.382	2563.58	2676.1	1563.21	1213.88	1681.81	1443.66	TP53BP1	tumor protein p53 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11999]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20915	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0035861//site of double-strand break;GO:0043229//intracellular organelle;GO:1990391//DNA repair complex"	GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0042162//telomeric DNA binding;GO:0042393//histone binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061649//ubiquitin modification-dependent histone binding	"GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0045830//positive regulation of isotype switching;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051260//protein homooligomerization;GO:0071481//cellular response to X-ray;GO:2000042//negative regulation of double-strand break repair via homologous recombination"	--
ENSG00000067445	24.912	23.887	25.332	24.554	28.877	28.49	1561	1467	1148	1119	1433	1333	TRO	trophinin [Source:HGNC Symbol;Acc:HGNC:12326]	-	-	-	-	GO:0005634//nucleus;GO:0031226//intrinsic component of plasma membrane	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007566//embryo implantation	--
ENSG00000067533	1.372	1.272	1.16	0.888	0.985	1.186	221	206	138	106	134	139	RRP15	ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255]	-	-	-	-	"GO:0030687//preribosome, large subunit precursor"	-	GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing	--
ENSG00000067560	211.19	212.481	226.458	222.772	216.998	223.855	8012	8095	6326	6245	6925	6169	RHOA	ras homolog family member A [Source:HGNC Symbol;Acc:HGNC:667]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Endocrine system;Cardiovascular disease;Circulatory system;Immune system;Nervous system;Signal transduction;Immune system;Immune system;Immune system;Endocrine system;Digestive system;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Infectious disease: bacterial;Cellular community - eukaryotes	"ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05100//Bacterial invasion of epithelial cells;ko05133//Pertussis;ko04520//Adherens junction"	K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030496//midbody;GO:0030667//secretory granule membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043296//apical junction complex;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0101003//ficolin-1-rich granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0017022//myosin binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0051022//Rho GDP-dissociation inhibitor binding	"GO:0000902//cell morphogenesis;GO:0001666//response to hypoxia;GO:0001822//kidney development;GO:0001998//angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0002363//alpha-beta T cell lineage commitment;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0007519//skeletal muscle tissue development;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008360//regulation of cell shape;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009749//response to glucose;GO:0010812//negative regulation of cell-substrate adhesion;GO:0010975//regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0016477//cell migration;GO:0021762//substantia nigra development;GO:0021795//cerebral cortex cell migration;GO:0021861//forebrain radial glial cell differentiation;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0030521//androgen receptor signaling pathway;GO:0030838//positive regulation of actin filament polymerization;GO:0030865//cortical cytoskeleton organization;GO:0031098//stress-activated protein kinase signaling cascade;GO:0031122//cytoplasmic microtubule organization;GO:0031532//actin cytoskeleton reorganization;GO:0032467//positive regulation of cytokinesis;GO:0032956//regulation of actin cytoskeleton organization;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0033688//regulation of osteoblast proliferation;GO:0034329//cell junction assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035385//Roundabout signaling pathway;GO:0036089//cleavage furrow formation;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0042476//odontogenesis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043149//stress fiber assembly;GO:0043200//response to amino acid;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043297//apical junction assembly;GO:0043366//beta selection;GO:0043524//negative regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043542//endothelial cell migration;GO:0043931//ossification involved in bone maturation;GO:0044319//wound healing, spreading of cells;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045471//response to ethanol;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045727//positive regulation of translation;GO:0045785//positive regulation of cell adhesion;GO:0045792//negative regulation of cell size;GO:0045907//positive regulation of vasoconstriction;GO:0045987//positive regulation of smooth muscle contraction;GO:0046039//GTP metabolic process;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0050773//regulation of dendrite development;GO:0050919//negative chemotaxis;GO:0051301//cell division;GO:0051384//response to glucocorticoid;GO:0051496//positive regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0051924//regulation of calcium ion transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060193//positive regulation of lipase activity;GO:0060548//negative regulation of cell death;GO:0061383//trabecula morphogenesis;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071222//cellular response to lipopolysaccharide;GO:0071345//cellular response to cytokine stimulus;GO:0071803//positive regulation of podosome assembly;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0090307//mitotic spindle assembly;GO:0090324//negative regulation of oxidative phosphorylation;GO:0097498//endothelial tube lumen extension;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902766//skeletal muscle satellite cell migration;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903673//mitotic cleavage furrow formation;GO:1904695//positive regulation of vascular associated smooth muscle contraction;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:1905244//regulation of modification of synaptic structure;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton;GO:1990869//cellular response to chemokine;GO:2000177//regulation of neural precursor cell proliferation;GO:2000406//positive regulation of T cell migration"	--
ENSG00000067596	10.888	13.654	13.677	10.225	11.92	12.98	939	1089	879	723	843	789	DHX8	DEAH-box helicase 8 [Source:HGNC Symbol;Acc:HGNC:2749]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12818	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	"GO:0000390//spliceosomal complex disassembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000067606	22.221	23.151	24.698	28.675	25.223	25.386	1063.78	1151.14	896.01	1024.79	1048.63	902.03	PRKCZ	protein kinase C zeta [Source:HGNC Symbol;Acc:HGNC:9412]	Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Transport and catabolism;Signal transduction;Cardiovascular disease;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Endocrine system;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine and metabolic disease;Endocrine and metabolic disease;Endocrine and metabolic disease	ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko05415//Diabetic cardiomyopathy;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04910//Insulin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04931//Insulin resistance;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04930//Type II diabetes mellitus	K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952;K18952	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0031982//vesicle;GO:0035748//myelin sheath abaxonal region;GO:0043203//axon hillock;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045179//apical cortex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0070160//tight junction;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0120157//PAR polarity complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015459//potassium channel regulator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0043274//phospholipase binding;GO:0043560//insulin receptor substrate binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0001954//positive regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007616//long-term memory;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0030010//establishment of cell polarity;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031584//activation of phospholipase D activity;GO:0032148//activation of protein kinase B activity;GO:0032733//positive regulation of interleukin-10 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0032869//cellular response to insulin stimulus;GO:0034613//cellular protein localization;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0047496//vesicle transport along microtubule;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050806//positive regulation of synaptic transmission;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051222//positive regulation of protein transport;GO:0051346//negative regulation of hydrolase activity;GO:0051899//membrane depolarization;GO:0060081//membrane hyperpolarization;GO:0060291//long-term synaptic potentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070528//protein kinase C signaling;GO:0072659//protein localization to plasma membrane;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1990138//neuron projection extension;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000553//positive regulation of T-helper 2 cell cytokine production	--
ENSG00000067646	4.475	2.664	2.786	2.114	2.32	3.743	424	281	197	153	181	210	ZFY	zinc finger protein Y-linked [Source:HGNC Symbol;Acc:HGNC:12870]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0001541//ovarian follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0009791//post-embryonic development;GO:0035264//multicellular organism growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048599//oocyte development;GO:0048872//homeostasis of number of cells;GO:0060746//parental behavior"	zf-C2H2
ENSG00000067704	27.097	25.531	27.146	22.66	24.685	26.335	1984	1879	1468	1229	1527	1403	IARS2	"isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29685]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01870	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004822//isoleucine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006428//isoleucyl-tRNA aminoacylation;GO:0032543//mitochondrial translation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000067715	3.734	2.793	2.317	3.154	4.057	3.704	324	274	167	228	321	257	SYT1	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15290	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030285//integral component of synaptic vesicle membrane;GO:0030424//axon;GO:0030658//transport vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0042584//chromaffin granule membrane;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043229//intracellular organelle;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0070382//exocytic vesicle;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008022//protein C-terminus binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0030348//syntaxin-3 binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0048306//calcium-dependent protein binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0061891//calcium ion sensor activity"	"GO:0005513//detection of calcium ion;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007420//brain development;GO:0014059//regulation of dopamine secretion;GO:0016079//synaptic vesicle exocytosis;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0030154//cell differentiation;GO:0031340//positive regulation of vesicle fusion;GO:0033603//positive regulation of dopamine secretion;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0048278//vesicle docking;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0050806//positive regulation of synaptic transmission;GO:0051291//protein heterooligomerization;GO:0051592//response to calcium ion;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0061669//spontaneous neurotransmitter secretion;GO:0071277//cellular response to calcium ion;GO:0071911//synchronous neurotransmitter secretion;GO:0098746//fast, calcium ion-dependent exocytosis of neurotransmitter;GO:0099502//calcium-dependent activation of synaptic vesicle fusion;GO:1903235//positive regulation of calcium ion-dependent exocytosis of neurotransmitter;GO:1903305//regulation of regulated secretory pathway;GO:1903861//positive regulation of dendrite extension;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000067798	19.674	15.848	19.498	12.09	14.543	15.847	2043	1649	1477	1074	1290	1265	NAV3	neuron navigator 3 [Source:HGNC Symbol;Acc:HGNC:15998]	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0016020//membrane;GO:1990752//microtubule end	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007026//negative regulation of microtubule depolymerization;GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0030336//negative regulation of cell migration;GO:0031116//positive regulation of microtubule polymerization;GO:0032703//negative regulation of interleukin-2 production	--
ENSG00000067829	35.314	39.605	42.701	48.002	47.035	40.383	984	1112	869	985	1112	818	IDH3G	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:5386]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K00030;K00030;K00030;K00030;K00030	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005962//mitochondrial isocitrate dehydrogenase complex (NAD+)	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046872//metal ion binding;GO:0051287//NAD binding"	GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process	--
ENSG00000067836	24.403	23.891	28.816	33.298	26.627	33.62	711	705	592	713	650	698	ROGDI	rogdi atypical leucine zipper [Source:HGNC Symbol;Acc:HGNC:29478]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043291//RAVE complex;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding	GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0042475//odontogenesis of dentin-containing tooth	--
ENSG00000067840	0.418	0.382	0.59	0.723	0.598	0.198	32	29	34	29	39	11	PDZD4	PDZ domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21167]	-	-	-	-	GO:0005737//cytoplasm;GO:0005938//cell cortex	GO:0005515//protein binding	-	--
ENSG00000067842	8.377	8.78	5.714	2.697	2.922	1.971	772	831	409	184	221	132	ATP2B3	ATPase plasma membrane Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:816]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Digestive system;Endocrine system;Digestive system;Digestive system;Excretory system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04972//Pancreatic secretion;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099056//integral component of presynaptic membrane;GO:1903561//extracellular vesicle;GO:1990032//parallel fiber	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0015085//calcium ion transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0046872//metal ion binding;GO:1905056//P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0070588//calcium ion transmembrane transport;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1903779//regulation of cardiac conduction;GO:1990034//calcium ion export across plasma membrane	--
ENSG00000067900	7.202	5.017	3.714	3.188	3.772	4.751	944	559	390	306	429	462	ROCK1	Rho associated coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:10251]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cell motility;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Cancer: overview;Endocrine system;Circulatory system;Immune system;Signal transduction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration;ko04350//TGF-beta signaling pathway	K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514;K04514	GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0032059//bleb;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0106003//amyloid-beta complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0072518//Rho-dependent protein serine/threonine kinase activity;GO:0106310//protein serine kinase activity	GO:0000281//mitotic cytokinesis;GO:0001837//epithelial to mesenchymal transition;GO:0003180//aortic valve morphogenesis;GO:0003383//apical constriction;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006939//smooth muscle contraction;GO:0006996//organelle organization;GO:0007159//leukocyte cell-cell adhesion;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007266//Rho protein signal transduction;GO:0010506//regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010922//positive regulation of phosphatase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0022614//membrane to membrane docking;GO:0030036//actin cytoskeleton organization;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0031175//neuron projection development;GO:0032060//bleb assembly;GO:0032091//negative regulation of protein binding;GO:0032956//regulation of actin cytoskeleton organization;GO:0032970//regulation of actin filament-based process;GO:0035306//positive regulation of dephosphorylation;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0042326//negative regulation of phosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0045616//regulation of keratinocyte differentiation;GO:0045664//regulation of neuron differentiation;GO:0048598//embryonic morphogenesis;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0051451//myoblast migration;GO:0051492//regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0061157//mRNA destabilization;GO:0070168//negative regulation of biomineral tissue development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071559//response to transforming growth factor beta;GO:0072659//protein localization to plasma membrane;GO:0090521//glomerular visceral epithelial cell migration;GO:0097746//blood vessel diameter maintenance;GO:0110061//regulation of angiotensin-activated signaling pathway;GO:0140058//neuron projection arborization;GO:1900223//positive regulation of amyloid-beta clearance;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1901888//regulation of cell junction assembly;GO:1902003//regulation of amyloid-beta formation;GO:1902430//negative regulation of amyloid-beta formation;GO:1902992//negative regulation of amyloid precursor protein catabolic process;GO:1903140//regulation of establishment of endothelial barrier;GO:1903347//negative regulation of bicellular tight junction assembly;GO:1905205//positive regulation of connective tissue replacement;GO:1990776//response to angiotensin;GO:2000114//regulation of establishment of cell polarity;GO:2000145//regulation of cell motility	--
ENSG00000067955	9.052	5.851	6.696	6.335	4.184	4.554	344	340	252	223	229	206	CBFB	core-binding factor subunit beta [Source:HGNC Symbol;Acc:HGNC:1539]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016513//core-binding factor complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0030098//lymphocyte differentiation;GO:0030099//myeloid cell differentiation;GO:0043371//negative regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0060216//definitive hemopoiesis"	CBF
ENSG00000067992	3.442	3.28	3.455	2.552	2.561	2.725	739	592	478	346	430	376	PDK3	pyruvate dehydrogenase kinase 3 [Source:HGNC Symbol;Acc:HGNC:8811]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K00898	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006468//protein phosphorylation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0010906//regulation of glucose metabolic process;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0071333//cellular response to glucose stimulus;GO:0071398//cellular response to fatty acid;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000068001	33.724	38.126	37.116	31.187	32.061	31.003	1325	1451	1076	991	1149	924	HYAL2	hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:5321]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01197;K01197;K01197	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0001618//virus receptor activity;GO:0003713//transcription coactivator activity;GO:0003824//catalytic activity;GO:0004415//hyalurononglucosaminidase activity;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019899//enzyme binding;GO:0030294//receptor signaling protein tyrosine kinase inhibitor activity;GO:0030971//receptor tyrosine kinase binding;GO:0033906//hyaluronoglucuronidase activity;GO:0050431//transforming growth factor beta binding"	GO:0000302//response to reactive oxygen species;GO:0001822//kidney development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008152//metabolic process;GO:0009615//response to virus;GO:0010259//multicellular organism aging;GO:0010764//negative regulation of fibroblast migration;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0030214//hyaluronan catabolic process;GO:0030308//negative regulation of cell growth;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0035810//positive regulation of urine volume;GO:0042117//monocyte activation;GO:0042307//positive regulation of protein import into nucleus;GO:0043407//negative regulation of MAP kinase activity;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046677//response to antibiotic;GO:0046718//viral entry into host cell;GO:0048705//skeletal system morphogenesis;GO:0050729//positive regulation of inflammatory response;GO:0051216//cartilage development;GO:0051607//defense response to virus;GO:0051898//negative regulation of protein kinase B signaling;GO:0060586//multicellular organismal iron ion homeostasis;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0070295//renal water absorption;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071493//cellular response to UV-B;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000068024	2.644	2.575	2.628	2.414	2.633	2.506	468	459	350	319	396	324	HDAC4	histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Immune system;Cancer: overview;Substance dependence;Cancer: overview;Signal transduction	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism;ko05206//MicroRNAs in cancer;ko04371//Apelin signaling pathway	K11406;K11406;K11406;K11406;K11406	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0017053//transcription repressor complex;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0031594//neuromuscular junction;GO:0031672//A band;GO:0032991//protein-containing complex;GO:0042641//actomyosin	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0019789//SUMO transferase activity;GO:0019901//protein kinase binding;GO:0030955//potassium ion binding;GO:0033558//protein deacetylase activity;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0002076//osteoblast development;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006476//protein deacetylation;GO:0006954//inflammatory response;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010592//positive regulation of lamellipodium assembly;GO:0010832//negative regulation of myotube differentiation;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016575//histone deacetylation;GO:0016925//protein sumoylation;GO:0019222//regulation of metabolic process;GO:0030183//B cell differentiation;GO:0033235//positive regulation of protein sumoylation;GO:0034983//peptidyl-lysine deacetylation;GO:0040029//regulation of gene expression, epigenetic;GO:0042113//B cell activation;GO:0043393//regulation of protein binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0045820//negative regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048742//regulation of skeletal muscle fiber development;GO:0050896//response to stimulus;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051153//regulation of striated muscle cell differentiation;GO:0070555//response to interleukin-1;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0071260//cellular response to mechanical stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0071374//cellular response to parathyroid hormone stimulus;GO:1902437//positive regulation of male mating behavior;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1903428//positive regulation of reactive oxygen species biosynthetic process"	--
ENSG00000068028	2.442	2.976	2.824	2.482	2.373	2.892	89	109	76	67	73	77	RASSF1	Ras association domain family member 1 [Source:HGNC Symbol;Acc:HGNC:9882]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: overview;Signal transduction;Cancer: specific types;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko05206//MicroRNAs in cancer;ko04390//Hippo signaling pathway;ko05223//Non-small cell lung cancer;ko05219//Bladder cancer;ko04392//Hippo signaling pathway - multiple species	K09850;K09850;K09850;K09850;K09850;K09850;K09850	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding	GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0031398//positive regulation of protein ubiquitination;GO:0050821//protein stabilization;GO:0051726//regulation of cell cycle;GO:0070507//regulation of microtubule cytoskeleton organization;GO:1902806//regulation of cell cycle G1/S phase transition	--
ENSG00000068078	10.167	9.759	8.882	5.282	5.941	5.503	826	864	522	306	403	315	FGFR3	fibroblast growth factor receptor 3 [Source:HGNC Symbol;Acc:HGNC:3690]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Transport and catabolism;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05206//MicroRNAs in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05230//Central carbon metabolism in cancer;ko05219//Bladder cancer	K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094;K05094	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding	GO:0000165//MAPK cascade;GO:0001501//skeletal system development;GO:0001958//endochondral ossification;GO:0002062//chondrocyte differentiation;GO:0003416//endochondral bone growth;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010518//positive regulation of phospholipase activity;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030282//bone mineralization;GO:0033674//positive regulation of kinase activity;GO:0035988//chondrocyte proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0046777//protein autophosphorylation;GO:0048513//animal organ development;GO:0048640//negative regulation of developmental growth;GO:0060349//bone morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070977//bone maturation;GO:0071363//cellular response to growth factor stimulus;GO:0071495//cellular response to endogenous stimulus;GO:1902178//fibroblast growth factor receptor apoptotic signaling pathway	--
ENSG00000068079	8.77	8.83	10.418	13.674	10.488	11.055	222	225	195	257	224	204	IFI35	interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0008285//negative regulation of cell population proliferation;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0050729//positive regulation of inflammatory response;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000068097	6.343	7.736	6.989	7.211	7.506	7.617	571	644	440	407	482	456	HEATR6	HEAT repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:24076]	-	-	-	-	-	GO:0003723//RNA binding	-	--
ENSG00000068120	28.632	32.677	32.015	32.962	32.401	32.047	1329	1457	1085	1135	1260	1028	COASY	Coenzyme A synthase [Source:HGNC Symbol;Acc:HGNC:29932]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K02318;K02318	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004140//dephospho-CoA kinase activity;GO:0004595//pantetheine-phosphate adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006796//phosphate-containing compound metabolic process;GO:0008152//metabolic process;GO:0009058//biosynthetic process;GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000068137	4.725	5.168	7.348	5.548	5.493	8.198	287	285	299	233	253	346	PLEKHH3	"pleckstrin homology, MyTH4 and FERM domain containing H3 [Source:HGNC Symbol;Acc:HGNC:26105]"	-	-	-	-	GO:0005615//extracellular space;GO:0005856//cytoskeleton	-	GO:0007165//signal transduction	--
ENSG00000068305	18.231	15.267	15.61	14.188	15.997	17.451	1642.33	1308.53	967.16	945.66	1177.36	1125.79	MEF2A	myocyte enhancer factor 2A [Source:HGNC Symbol;Acc:HGNC:6993]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Cardiovascular disease;Endocrine system	"ko04022//cGMP-PKG signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04928//Parathyroid hormone synthesis, secretion and action"	K09260;K09260;K09260;K09260	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0043229//intracellular organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035035//histone acetyltransferase binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000002//mitochondrial genome maintenance;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0048311//mitochondrion distribution;GO:0048513//animal organ development;GO:0048813//dendrite morphogenesis;GO:0055005//ventricular cardiac myofibril assembly;GO:0061337//cardiac conduction;GO:0070375//ERK5 cascade;GO:0071277//cellular response to calcium ion"	SRF
ENSG00000068308	23.891	22.271	21.935	24.395	25.164	25.422	1168	1091	865	884	1080	906	OTUD5	OTU deubiquitinase 5 [Source:HGNC Symbol;Acc:HGNC:25402]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12655	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0101005//deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0014033//neural crest cell differentiation;GO:0016579//protein deubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904263//positive regulation of TORC1 signaling;GO:1904515//positive regulation of TORC2 signaling	--
ENSG00000068323	25.408	24.814	26.939	30.932	30.064	28.364	1732	1700	1356	1561	1731	1407	TFE3	transcription factor binding to IGHM enhancer 3 [Source:HGNC Symbol;Acc:HGNC:11752]	Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Transport and catabolism;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma	K09105;K09105;K09105	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006959//humoral immune response;GO:0045670//regulation of osteoclast differentiation;GO:0045785//positive regulation of cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090336//positive regulation of brown fat cell differentiation;GO:0120163//negative regulation of cold-induced thermogenesis"	bHLH
ENSG00000068354	4.788	3.752	5.132	5.177	6.021	5.192	322	286	229	236.98	255.95	237	TBC1D25	TBC1 domain family member 25 [Source:HGNC Symbol;Acc:HGNC:8092]	-	-	-	-	GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0031410//cytoplasmic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006914//autophagy;GO:0090630//activation of GTPase activity;GO:1901096//regulation of autophagosome maturation	--
ENSG00000068366	10.143	6.894	6.553	4.927	5.22	5.54	985	702	436	367	447	406	ACSL4	acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0090433//palmitoyl-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008610//lipid biosynthetic process;GO:0030182//neuron differentiation;GO:0030307//positive regulation of cell growth;GO:0032024//positive regulation of insulin secretion;GO:0032307//negative regulation of prostaglandin secretion;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0060136//embryonic process involved in female pregnancy	--
ENSG00000068383	15.336	14.75	14.765	13.972	13.943	16.363	926	903	649	644	733	713	INPP5A	inositol polyphosphate-5-phosphatase A [Source:HGNC Symbol;Acc:HGNC:6076]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism	Global and overview maps;Endocrine system;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04910//Insulin signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01106;K01106;K01106;K01106	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0042995//cell projection	"GO:0003824//catalytic activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042731//PH domain binding;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"	GO:0006796//phosphate-containing compound metabolic process;GO:0016311//dephosphorylation;GO:0019637//organophosphate metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048016//inositol phosphate-mediated signaling;GO:1901215//negative regulation of neuron death	--
ENSG00000068394	8.549	10.096	10.591	8.793	9.155	8.912	294	349	269	224	266	223	GPKOW	G-patch domain and KOW motifs [Source:HGNC Symbol;Acc:HGNC:30677]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000068400	9.321	10.633	11.201	8.526	8.905	9.943	555	652	512	373	473	420	GRIPAP1	GRIP1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18706]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0055038//recycling endosome membrane;GO:0072562//blood microparticle;GO:0098837//postsynaptic recycling endosome;GO:0098978//glutamatergic synapse;GO:0098998//extrinsic component of postsynaptic early endosome membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0008150//biological_process;GO:0015031//protein transport;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099152//regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099158//regulation of recycling endosome localization within postsynapse;GO:1905244//regulation of modification of synaptic structure"	--
ENSG00000068438	9.318	9.491	9.43	7.471	7.953	7.344	368	377	276	219	266	212	FTSJ1	FtsJ RNA 2'-O-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:13254]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0009020//tRNA (guanosine-2'-O-)-methyltransferase activity;GO:0016740//transferase activity;GO:0052666//tRNA (cytosine-2'-O-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0002128//tRNA nucleoside ribose methylation;GO:0002181//cytoplasmic translation;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0043414//macromolecule methylation;GO:0090304//nucleic acid metabolic process	--
ENSG00000068489	0.738	0.367	0.21	0.486	0.525	0.271	31	24	15	21	28	12	PRR11	proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	-	GO:0051726//regulation of cell cycle	--
ENSG00000068615	11.788	12.599	11.077	7.275	6.978	8.438	673	718	418	296	372	345	REEP1	receptor accessory protein 1 [Source:HGNC Symbol;Acc:HGNC:25786]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031849//olfactory receptor binding	GO:0051205//protein insertion into membrane;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000068650	6.806	6.241	6.162	5.426	5.296	6.071	1104	1036	743	585	764	747	ATP11A	ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:0070821//tertiary granule membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090555//phosphatidylethanolamine flippase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140346//phosphatidylserine flippase activity	GO:0001701//in utero embryonic development;GO:0006869//lipid transport;GO:0010831//positive regulation of myotube differentiation;GO:0015914//phospholipid transport;GO:0045332//phospholipid translocation;GO:0140331//aminophospholipid translocation	--
ENSG00000068654	9.798	10.349	10.712	8.958	10.537	10.145	2031	2137	1577	1418	1723	1503	POLR1A	RNA polymerase I subunit A [Source:HGNC Symbol;Acc:HGNC:17264]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K02999	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex;GO:0031981//nuclear lumen	GO:0001054//RNA polymerase I activity;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006360//transcription by RNA polymerase I;GO:1904750//negative regulation of protein localization to nucleolus"	--
ENSG00000068697	223.008	222.36	220.364	237.886	225.249	250.965	6314	6328	4608	4989	5388	5170	LAPTM4A	lysosomal protein transmembrane 4 alpha [Source:HGNC Symbol;Acc:HGNC:6924]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12387	GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	-	--
ENSG00000068724	10.23	10.159	11.621	11.587	13.631	13.74	926	944	806	771	986	869	TTC7A	tetratricopeptide repeat domain 7A [Source:HGNC Symbol;Acc:HGNC:19750]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0006879//cellular iron ion homeostasis;GO:0030097//hemopoiesis;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000068745	41.054	41.176	43.661	38.957	37.461	39.111	1312	1310	1028	947	1035	915	IP6K2	inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313]	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K07756	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030054//cell junction	"GO:0000166//nucleotide binding;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0000829//inositol heptakisphosphate kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0052836//inositol 5-diphosphate pentakisphosphate 5-kinase activity;GO:0052839//inositol diphosphate tetrakisphosphate kinase activity;GO:0097243//flavonoid binding"	GO:0006629//lipid metabolic process;GO:0006817//phosphate ion transport;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0032958//inositol phosphate biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:1905396//cellular response to flavonoid	--
ENSG00000068781	0.102	0.466	0.069	0	0.308	0.383	8.02	37.11	3.71	0	20.43	21.93	STON1-GTF2A1L	STON1-GTF2A1L readthrough [Source:HGNC Symbol;Acc:HGNC:30651]	-	-	-	-	GO:0005634//nucleus;GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm	-	GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006897//endocytosis	--
ENSG00000068784	4.325	3.139	3.08	2.094	2.397	2.963	329	240	173	118	154	164	SRBD1	S1 RNA binding domain 1 [Source:HGNC Symbol;Acc:HGNC:25521]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome	GO:0006139//nucleobase-containing compound metabolic process;GO:0006412//translation	--
ENSG00000068796	12.198	9.439	8.367	6.928	7.241	7.671	1126.22	753.25	551.44	453.23	526.56	476.22	KIF2A	kinesin family member 2A [Source:HGNC Symbol;Acc:HGNC:6318]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K10393	GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0016604//nuclear body;GO:0120103//centriolar subdistal appendage	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0000226//microtubule cytoskeleton organization;GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0051301//cell division;GO:0090307//mitotic spindle assembly	--
ENSG00000068831	0.183	0.582	0.498	0.553	1.091	1.003	3	15	9	6	12	15	RASGRP2	RAS guanyl releasing protein 2 [Source:HGNC Symbol;Acc:HGNC:9879]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Immune system;Immune system	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04062//Chemokine signaling pathway;ko04611//Platelet activation	K12361;K12361;K12361;K12361;K12361;K12361	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0008289//lipid binding;GO:0019992//diacylglycerol binding;GO:0046872//metal ion binding	GO:0001558//regulation of cell growth;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0071277//cellular response to calcium ion	--
ENSG00000068878	13.272	11.708	10.743	8.34	9.154	8.966	1973	1722	1171	913	1163	981	PSME4	proteasome activator subunit 4 [Source:HGNC Symbol;Acc:HGNC:20635]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K06699	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:1990111//spermatoproteasome complex	GO:0005515//protein binding;GO:0016504//peptidase activator activity;GO:0070577//lysine-acetylated histone binding;GO:0070628//proteasome binding	"GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:0010952//positive regulation of peptidase activity;GO:0030154//cell differentiation;GO:0035093//spermatogenesis, exchange of chromosomal proteins"	--
ENSG00000068885	13.15	9.216	8.261	7.187	7.893	8.173	912.63	689	482.84	355.25	512.42	469.87	IFT80	intraflagellar transport 80 [Source:HGNC Symbol;Acc:HGNC:29262]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097731//9+0 non-motile cilium	GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0002062//chondrocyte differentiation;GO:0003417//growth plate cartilage development;GO:0003418//growth plate cartilage chondrocyte differentiation;GO:0007224//smoothened signaling pathway;GO:0033687//osteoblast proliferation;GO:0035630//bone mineralization involved in bone maturation;GO:0035720//intraciliary anterograde transport;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060173//limb development;GO:0060271//cilium assembly;GO:0060349//bone morphogenesis;GO:0061975//articular cartilage development;GO:0097500//receptor localization to non-motile cilium;GO:1905515//non-motile cilium assembly;GO:2000051//negative regulation of non-canonical Wnt signaling pathway	--
ENSG00000068903	37.35	36.08	40.267	47.754	46.791	47.289	1499	1475	1191	1423	1599	1421	SIRT2	sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K11412;K11412	"GO:0000781//chromosome, telomeric region;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005677//chromatin silencing complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030426//growth cone;GO:0030496//midbody;GO:0033010//paranodal junction;GO:0033270//paranode region of axon;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043209//myelin sheath;GO:0043219//lateral loop;GO:0043220//Schmidt-Lanterman incisure;GO:0044224//juxtaparanode region of axon;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle;GO:0072687//meiotic spindle;GO:0097386//glial cell projection"	GO:0003682//chromatin binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0033558//protein deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0035035//histone acetyltransferase binding;GO:0042826//histone deacetylase binding;GO:0042903//tubulin deacetylase activity;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0051287//NAD binding;GO:0070403//NAD+ binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000183//rDNA heterochromatin assembly;GO:0002376//immune system process;GO:0006471//protein ADP-ribosylation;GO:0006476//protein deacetylation;GO:0006914//autophagy;GO:0007049//cell cycle;GO:0007084//mitotic nuclear membrane reassembly;GO:0007096//regulation of exit from mitosis;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0010507//negative regulation of autophagy;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016575//histone deacetylation;GO:0021762//substantia nigra development;GO:0022011//myelination in peripheral nervous system;GO:0030154//cell differentiation;GO:0031507//heterochromatin assembly;GO:0031509//subtelomeric heterochromatin assembly;GO:0031641//regulation of myelination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034599//cellular response to oxidative stress;GO:0034983//peptidyl-lysine deacetylation;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0042177//negative regulation of protein catabolic process;GO:0042325//regulation of phosphorylation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043388//positive regulation of DNA binding;GO:0043491//protein kinase B signaling;GO:0044242//cellular lipid catabolic process;GO:0045087//innate immune response;GO:0045598//regulation of fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045836//positive regulation of meiotic nuclear division;GO:0045843//negative regulation of striated muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051726//regulation of cell cycle;GO:0051775//response to redox state;GO:0051781//positive regulation of cell division;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0061433//cellular response to caloric restriction;GO:0070446//negative regulation of oligodendrocyte progenitor proliferation;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0071219//cellular response to molecule of bacterial origin;GO:0071456//cellular response to hypoxia;GO:0071872//cellular response to epinephrine stimulus;GO:0090042//tubulin deacetylation;GO:1900119//positive regulation of execution phase of apoptosis;GO:1900195//positive regulation of oocyte maturation;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1900425//negative regulation of defense response to bacterium;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000777//positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia"	--
ENSG00000068912	35.122	34.412	30.432	27.316	29.026	29.318	1741	1694	1103	1020	1197	1070	ERLEC1	endoplasmic reticulum lectin 1 [Source:HGNC Symbol;Acc:HGNC:25222]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14008	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0044322//endoplasmic reticulum quality control compartment	GO:0005515//protein binding;GO:0051082//unfolded protein binding	"GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036503//ERAD pathway;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000068971	7.862	7.532	8.458	8.077	8.459	8.425	445	412	349	332	395	347	PPP2R5B	protein phosphatase 2 regulatory subunit B'beta [Source:HGNC Symbol;Acc:HGNC:9310]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11584;K11584;K11584;K11584;K11584;K11584;K11584;K11584	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity	GO:0001932//regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0010469//regulation of signaling receptor activity;GO:0010976//positive regulation of neuron projection development;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031952//regulation of protein autophosphorylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050790//regulation of catalytic activity;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0051726//regulation of cell cycle;GO:0070317//negative regulation of G0 to G1 transition;GO:0071363//cellular response to growth factor stimulus	--
ENSG00000068976	25.418	26.945	30.849	37.834	35.86	34.679	1511	1610	1354	1666	1801	1500	PYGM	"glycogen phosphorylase, muscle associated [Source:HGNC Symbol;Acc:HGNC:9726]"	Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cell growth and death;Endocrine system;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04217//Necroptosis;ko04910//Insulin signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00500//Starch and sucrose metabolism	K00688;K00688;K00688;K00688;K00688;K00688	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004645//1,4-alpha-oligoglucan phosphorylase activity;GO:0005515//protein binding;GO:0008184//glycogen phosphorylase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity"	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0008152//metabolic process	--
ENSG00000068985	0	0	0	0	0	0	0	0	0	0	0	0	PAGE1	PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000069011	0	0	0.028	0	0.146	0	0	0	1	0	5	0	PITX1	paired like homeodomain 1 [Source:HGNC Symbol;Acc:HGNC:9004]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0014707//branchiomeric skeletal muscle development;GO:0021983//pituitary gland development;GO:0035116//embryonic hindlimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048625//myoblast fate commitment;GO:0051216//cartilage development"	Homeobox
ENSG00000069018	0.019	0.027	0	0	0	0.065	1	2	0	0	0	2	TRPC7	transient receptor potential cation channel subfamily C member 7 [Source:HGNC Symbol;Acc:HGNC:20754]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005801//cis-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034703//cation channel complex;GO:0048471//perinuclear region of cytoplasm	"GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0007338//single fertilization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000069020	4.345	4.015	2.621	5.403	4.179	3.346	457	465	349	275	413	317	MAST4	microtubule associated serine/threonine kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:19037]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000069122	0	0.059	0.012	0.057	0.06	0.047	0	7	1	5	6	4	ADGRF5	adhesion G protein-coupled receptor F5 [Source:HGNC Symbol;Acc:HGNC:19030]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0003094//glomerular filtration;GO:0006112//energy reserve metabolic process;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0042593//glucose homeostasis;GO:0043031//negative regulation of macrophage activation;GO:0043129//surfactant homeostasis;GO:0045444//fat cell differentiation;GO:0048821//erythrocyte development;GO:0061626//pharyngeal arch artery morphogenesis;GO:0071073//positive regulation of phospholipid biosynthetic process	--
ENSG00000069188	1.554	2.11	2.168	3.498	3.986	3.48	345	386	258	488	649	482	SDK2	sidekick cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:19308]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0010842//retina layer formation;GO:0060219//camera-type eye photoreceptor cell differentiation	--
ENSG00000069206	0	0	0	0	0	0	0	0	0	0	0	0	ADAM7	ADAM metallopeptidase domain 7 [Source:HGNC Symbol;Acc:HGNC:214]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis	--
ENSG00000069248	11.71	11.448	11.343	10.26	10.519	10.764	1265	1243	905	821	960	846	NUP133	nucleoporin 133 [Source:HGNC Symbol;Acc:HGNC:18016]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14300;K14300	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane"	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0000972//transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0021915//neural tube development;GO:0022008//neurogenesis;GO:0048339//paraxial mesoderm development;GO:0051028//mRNA transport;GO:0061053//somite development;GO:0072006//nephron development	--
ENSG00000069275	49.485	46.106	43.845	38.895	41.325	36.666	6568	6151	4298	3824	4634	3541	NUCKS1	nuclear casein kinase and cyclin dependent kinase substrate 1 [Source:HGNC Symbol;Acc:HGNC:29923]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0140297//DNA-binding transcription factor binding	GO:0000724//double-strand break repair via homologous recombination;GO:0001678//cellular glucose homeostasis;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0019046//release from viral latency;GO:0031297//replication fork processing;GO:0035822//gene conversion;GO:0036297//interstrand cross-link repair;GO:0042593//glucose homeostasis;GO:0043923//positive regulation by host of viral transcription;GO:0044829//positive regulation by host of viral genome replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0060382//regulation of DNA strand elongation;GO:0071481//cellular response to X-ray;GO:1990968//modulation by host of RNA binding by virus;GO:1990969//modulation by host of viral RNA-binding transcription factor activity	--
ENSG00000069329	34.613	31.636	29.35	24.865	24.141	24.826	3124	2844	1986	1698	1867	1651	VPS35	VPS35 retromer complex component [Source:HGNC Symbol;Acc:HGNC:13487]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18468	"GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030904//retromer complex;GO:0030906//retromer, cargo-selective complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097422//tubular endosome;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099073//mitochondrion-derived vesicle"	GO:0005515//protein binding;GO:0031748//D1 dopamine receptor binding	"GO:0006886//intracellular protein transport;GO:0007040//lysosome organization;GO:0007416//synapse assembly;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010821//regulation of mitochondrion organization;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0016241//regulation of macroautophagy;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0032268//regulation of cellular protein metabolic process;GO:0032456//endocytic recycling;GO:0032463//negative regulation of protein homooligomerization;GO:0033365//protein localization to organelle;GO:0036010//protein localization to endosome;GO:0042147//retrograde transport, endosome to Golgi;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0045056//transcytosis;GO:0050728//negative regulation of inflammatory response;GO:0050882//voluntary musculoskeletal movement;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0060548//negative regulation of cell death;GO:0061357//positive regulation of Wnt protein secretion;GO:0090141//positive regulation of mitochondrial fission;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090326//positive regulation of locomotion involved in locomotory behavior;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse;GO:0099074//mitochondrion to lysosome transport;GO:0099639//neurotransmitter receptor transport, endosome to plasma membrane;GO:1901215//negative regulation of neuron death;GO:1902823//negative regulation of late endosome to lysosome transport;GO:1902950//regulation of dendritic spine maintenance;GO:1903181//positive regulation of dopamine biosynthetic process;GO:1903364//positive regulation of cellular protein catabolic process;GO:1903828//negative regulation of cellular protein localization;GO:1905166//negative regulation of lysosomal protein catabolic process;GO:1905606//regulation of presynapse assembly;GO:2000331//regulation of terminal button organization"	--
ENSG00000069345	31.5	28.969	30.228	25.625	25.397	31.348	1707	1542	1266	1033	1120	1281	DNAJA2	DnaJ heat shock protein family (Hsp40) member A2 [Source:HGNC Symbol;Acc:HGNC:14884]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09503	GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0008284//positive regulation of cell population proliferation;GO:0009408//response to heat;GO:0042026//protein refolding	--
ENSG00000069399	4.303	4.191	3.617	3.178	3.101	3.707	160	164	104	85	102	105	BCL3	BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04668//TNF signaling pathway;ko04625//C-type lectin receptor signaling pathway	K09258;K09258	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0032996//Bcl3-Bcl10 complex;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	"GO:0002268//follicular dendritic cell differentiation;GO:0002315//marginal zone B cell differentiation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002467//germinal center formation;GO:0006606//protein import into nucleus;GO:0006974//cellular response to DNA damage stimulus;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009615//response to virus;GO:0010225//response to UV-C;GO:0019730//antimicrobial humoral response;GO:0030198//extracellular matrix organization;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0042088//T-helper 1 type immune response;GO:0042742//defense response to bacterium;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0042832//defense response to protozoan;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045064//T-helper 2 cell differentiation;GO:0045727//positive regulation of translation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0048536//spleen development;GO:0051101//regulation of DNA binding;GO:1901222//regulation of NIK/NF-kappaB signaling"	--
ENSG00000069424	17.423	20.565	17.295	20.495	22.511	21.749	1136	1234	856	1024	1195	1039	KCNAB2	potassium voltage-gated channel subfamily A regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6229]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044224//juxtaparanode region of axon;GO:0045202//synapse;GO:0070821//tertiary granule membrane;GO:1990031//pinceau fiber	GO:0004033//aldo-keto reductase (NADP) activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0016491//oxidoreductase activity;GO:0044325//transmembrane transporter binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070995//NADPH oxidation;GO:0071805//potassium ion transmembrane transport;GO:0098900//regulation of action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:2000008//regulation of protein localization to cell surface	--
ENSG00000069431	3.809	3.15	3.894	1.712	2.571	2.3	544.48	439.82	346.76	190.44	297.25	212.77	ABCC9	ATP binding cassette subfamily C member 9 [Source:HGNC Symbol;Acc:HGNC:60]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05033	GO:0005886//plasma membrane;GO:0008282//inward rectifying potassium channel;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030017//sarcomere;GO:0031004//potassium ion-transporting ATPase complex	GO:0000166//nucleotide binding;GO:0005261//cation channel activity;GO:0005267//potassium channel activity;GO:0005524//ATP binding;GO:0008281//sulfonylurea receptor activity;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0015459//potassium channel regulator activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0044325//transmembrane transporter binding;GO:0140359//ABC-type transporter activity	GO:0006813//potassium ion transport;GO:0015698//inorganic anion transport;GO:0033198//response to ATP;GO:0045776//negative regulation of blood pressure;GO:0051607//defense response to virus;GO:0055085//transmembrane transport;GO:0061337//cardiac conduction;GO:0071805//potassium ion transmembrane transport;GO:0086003//cardiac muscle cell contraction;GO:0098655//cation transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1903760//regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000069482	3.347	3.906	3.225	5.04	3.886	3.185	52	61	37	58	51	36	GAL	galanin and GMAP prepropeptide [Source:HGNC Symbol;Acc:HGNC:4114]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05244	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0030141//secretory granule;GO:0043025//neuronal cell body	GO:0004966//galanin receptor activity;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0031763//galanin receptor binding;GO:0031764//type 1 galanin receptor binding;GO:0031765//type 2 galanin receptor binding;GO:0031766//type 3 galanin receptor binding	GO:0006954//inflammatory response;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010737//protein kinase A signaling;GO:0019933//cAMP-mediated signaling;GO:0030073//insulin secretion;GO:0031943//regulation of glucocorticoid metabolic process;GO:0032868//response to insulin;GO:0035902//response to immobilization stress;GO:0043065//positive regulation of apoptotic process;GO:0043627//response to estrogen;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050672//negative regulation of lymphocyte proliferation;GO:0051464//positive regulation of cortisol secretion;GO:0051795//positive regulation of timing of catagen;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity	--
ENSG00000069493	1.524	0.436	0.876	0.878	0.853	0.96	31	18	23	20	26	28	CLEC2D	C-type lectin domain family 2 member D [Source:HGNC Symbol;Acc:HGNC:14351]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000069509	12.396	10.148	11.767	11.671	8.608	10.813	271	223	190	189	159	172	FUNDC1	FUN14 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28746]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K17986	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0005515//protein binding	GO:0000422//autophagy of mitochondrion;GO:0001666//response to hypoxia;GO:0006914//autophagy;GO:0010243//response to organonitrogen compound	--
ENSG00000069535	13.375	13.699	13.386	9.269	10.214	10.081	713	734	527	366	460	391	MAOB	monoamine oxidase B [Source:HGNC Symbol;Acc:HGNC:6834]	Metabolism;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Substance dependence;Nervous system;Nervous system;Xenobiotics biodegradation and metabolism;Substance dependence;Amino acid metabolism;Substance dependence;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko00982//Drug metabolism - cytochrome P450;ko05031//Amphetamine addiction;ko00330//Arginine and proline metabolism;ko05030//Cocaine addiction;ko00380//Tryptophan metabolism;ko00260//Glycine, serine and threonine metabolism;ko00350//Tyrosine metabolism;ko00340//Histidine metabolism;ko00360//Phenylalanine metabolism"	K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008131//primary amine oxidase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0097621//monoamine oxidase activity	GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010044//response to aluminum ion;GO:0010269//response to selenium ion;GO:0014063//negative regulation of serotonin secretion;GO:0021762//substantia nigra development;GO:0022900//electron transport chain;GO:0032496//response to lipopolysaccharide;GO:0042135//neurotransmitter catabolic process;GO:0042420//dopamine catabolic process;GO:0045471//response to ethanol;GO:0045964//positive regulation of dopamine metabolic process;GO:0048545//response to steroid hormone;GO:0050665//hydrogen peroxide biosynthetic process;GO:0051412//response to corticosterone	--
ENSG00000069667	4.437	3.894	4.608	3.871	3.771	3.34	449	271	198	183	249	210	RORA	RAR related orphan receptor A [Source:HGNC Symbol;Acc:HGNC:10258]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Neurodegenerative disease;Immune system;Immune disease;Environmental adaptation	ko05017//Spinocerebellar ataxia;ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease;ko04710//Circadian rhythm	K08532;K08532;K08532;K08532	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001222//transcription corepressor binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008142//oxysterol binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0098531//ligand-activated transcription factor activity"	"GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006805//xenobiotic metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0008589//regulation of smoothened signaling pathway;GO:0010468//regulation of gene expression;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010906//regulation of glucose metabolic process;GO:0019218//regulation of steroid metabolic process;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021930//cerebellar granule cell precursor proliferation;GO:0030522//intracellular receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0036315//cellular response to sterol;GO:0042632//cholesterol homeostasis;GO:0042692//muscle cell differentiation;GO:0042752//regulation of circadian rhythm;GO:0042753//positive regulation of circadian rhythm;GO:0043030//regulation of macrophage activation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045599//negative regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046068//cGMP metabolic process;GO:0048511//rhythmic process;GO:0050728//negative regulation of inflammatory response;GO:0070328//triglyceride homeostasis;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071456//cellular response to hypoxia;GO:0072539//T-helper 17 cell differentiation"	THR-like
ENSG00000069696	17.231	19.748	21.464	21.122	17.947	18.519	500	576	460	454	440	391	DRD4	dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04728//Dopaminergic synapse	K04147;K04147	GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	"GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930//G protein-coupled receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0017124//SH3 domain binding;GO:0030594//neurotransmitter receptor activity;GO:0035240//dopamine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding"	"GO:0001662//behavioral fear response;GO:0001963//synaptic transmission, dopaminergic;GO:0001975//response to amphetamine;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0008344//adult locomotory behavior;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0033674//positive regulation of kinase activity;GO:0034776//response to histamine;GO:0035176//social behavior;GO:0042053//regulation of dopamine metabolic process;GO:0042417//dopamine metabolic process;GO:0042596//fear response;GO:0042752//regulation of circadian rhythm;GO:0043406//positive regulation of MAP kinase activity;GO:0048148//behavioral response to cocaine;GO:0048149//behavioral response to ethanol;GO:0048511//rhythmic process;GO:0050482//arachidonic acid secretion;GO:0050709//negative regulation of protein secretion;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0060080//inhibitory postsynaptic potential;GO:0098664//G protein-coupled serotonin receptor signaling pathway;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1901386//negative regulation of voltage-gated calcium channel activity"	--
ENSG00000069702	8.566	7.75	9.683	7.618	8.843	11.355	993	899	811	672	833	965	TGFBR3	transforming growth factor beta receptor 3 [Source:HGNC Symbol;Acc:HGNC:11774]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0043235//receptor complex;GO:0070062//extracellular exosome	"GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0015026//coreceptor activity;GO:0017134//fibroblast growth factor binding;GO:0030165//PDZ domain binding;GO:0046332//SMAD binding;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding;GO:0070123//transforming growth factor beta receptor activity, type III"	GO:0001666//response to hypoxia;GO:0001837//epithelial to mesenchymal transition;GO:0001889//liver development;GO:0003007//heart morphogenesis;GO:0003150//muscular septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0006955//immune response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0016477//cell migration;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030509//BMP signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031100//animal organ regeneration;GO:0032354//response to follicle-stimulating hormone;GO:0034695//response to prostaglandin E;GO:0034699//response to luteinizing hormone;GO:0035556//intracellular signal transduction;GO:0043393//regulation of protein binding;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051271//negative regulation of cellular component movement;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060216//definitive hemopoiesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060318//definitive erythrocyte differentiation;GO:0060347//heart trabecula formation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060412//ventricular septum morphogenesis;GO:0060939//epicardium-derived cardiac fibroblast cell development;GO:0060979//vasculogenesis involved in coronary vascular morphogenesis;GO:0061384//heart trabecula morphogenesis;GO:0062009//secondary palate development;GO:0065003//protein-containing complex assembly	--
ENSG00000069764	0	0	0	0	0	0	0	0	0	0	0	0	PLA2G10	phospholipase A2 group X [Source:HGNC Symbol;Acc:HGNC:9029]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0001516//prostaglandin biosynthetic process;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006658//phosphatidylserine metabolic process;GO:0007411//axon guidance;GO:0009566//fertilization;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010884//positive regulation of lipid storage;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0031069//hair follicle morphogenesis;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032308//positive regulation of prostaglandin secretion;GO:0034374//low-density lipoprotein particle remodeling;GO:0034638//phosphatidylcholine catabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036335//intestinal stem cell homeostasis;GO:0042116//macrophage activation;GO:0042632//cholesterol homeostasis;GO:0043030//regulation of macrophage activation;GO:0043249//erythrocyte maturation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0046337//phosphatidylethanolamine metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0050482//arachidonic acid secretion;GO:0050728//negative regulation of inflammatory response;GO:0051607//defense response to virus;GO:0051977//lysophospholipid transport;GO:0062234//platelet activating factor catabolic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0090370//negative regulation of cholesterol efflux;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000069812	0	0	0	0	0	0	0	0	0	0	0	0	HES2	hes family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:16005]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K09087	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000069849	37.692	29.002	37.665	37.715	34.542	47.559	1445	1114	1066	1071	1118	1326	ATP1B3	ATPase Na+/K+ transporting subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:806]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0036126//sperm flagellum;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0051117//ATPase binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0030007//cellular potassium ion homeostasis;GO:0032781//positive regulation of ATPase activity;GO:0035725//sodium ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0050821//protein stabilization;GO:0071805//potassium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0086009//membrane repolarization;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000069869	1.847	1.569	1.594	0.753	1.154	1.074	220	189	140	67	116	93	NEDD4	NEDD4 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7727]	Human Diseases;Cellular Processes;Cellular Processes;Genetic Information Processing	"Infectious disease: viral;Transport and catabolism;Cellular community - eukaryotes;Folding, sorting and degradation"	ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko04530//Tight junction;ko04120//Ubiquitin mediated proteolysis	K10591;K10591;K10591;K10591	GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016327//apicolateral plasma membrane;GO:0032991//protein-containing complex;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019871//sodium channel inhibitor activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0043130//ubiquitin binding;GO:0050815//phosphoserine residue binding;GO:0050816//phosphothreonine residue binding;GO:0061630//ubiquitin protein ligase activity;GO:0070063//RNA polymerase binding;GO:0070064//proline-rich region binding	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006622//protein targeting to lysosome;GO:0007041//lysosomal transport;GO:0007399//nervous system development;GO:0007528//neuromuscular junction development;GO:0010766//negative regulation of sodium ion transport;GO:0010768//negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016241//regulation of macroautophagy;GO:0016567//protein ubiquitination;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031175//neuron projection development;GO:0031623//receptor internalization;GO:0032801//receptor catabolic process;GO:0034644//cellular response to UV;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0042921//glucocorticoid receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0044111//formation of structure involved in a symbiotic process;GO:0045732//positive regulation of protein catabolic process;GO:0046755//viral budding;GO:0046824//positive regulation of nucleocytoplasmic transport;GO:0048814//regulation of dendrite morphogenesis;GO:0050807//regulation of synapse organization;GO:0050847//progesterone receptor signaling pathway;GO:0051592//response to calcium ion;GO:0070534//protein K63-linked ubiquitination;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000069943	4.772	4.811	4.681	4.4	3.786	3.469	177.91	184.8	135.92	118.02	126.51	99.56	PIGB	phosphatidylinositol glycan anchor biosynthesis class B [Source:HGNC Symbol;Acc:HGNC:8959]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05286;K05286	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0004376//glycolipid mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0097502//mannosylation	--
ENSG00000069956	20.953	17.324	15.115	12.846	13.714	14.379	2318	1926	1235	1052	1281	1156	MAPK6	mitogen-activated protein kinase 6 [Source:HGNC Symbol;Acc:HGNC:6879]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K06855	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032156//septin cytoskeleton;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0060999//positive regulation of dendritic spine development	--
ENSG00000069966	15.735	13.969	14.533	13.92	13.543	15.714	728	655.02	532	497	533	538	GNB5	G protein subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:4401]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539;K04539	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0098793//presynapse;GO:1902773//GTPase activator complex	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0031682//G-protein gamma-subunit binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0036367//light adaption;GO:0043547//positive regulation of GTPase activity;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1990603//dark adaptation	--
ENSG00000069974	79.975	69.401	66.385	57.075	54.952	72.779	3870	3246	2402	2008	2257	2557	RAB27A	"RAB27A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9766]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0030667//secretory granule membrane;GO:0032585//multivesicular body membrane;GO:0033093//Weibel-Palade body;GO:0033162//melanosome membrane;GO:0035580//specific granule lumen;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0070382//exocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0019904//protein domain specific binding;GO:0031489//myosin V binding	GO:0006605//protein targeting;GO:0006887//exocytosis;GO:0007596//blood coagulation;GO:0010628//positive regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0019882//antigen processing and presentation;GO:0030318//melanocyte differentiation;GO:0032400//melanosome localization;GO:0032402//melanosome transport;GO:0036257//multivesicular body organization;GO:0043316//cytotoxic T cell degranulation;GO:0043320//natural killer cell degranulation;GO:0043473//pigmentation;GO:0045921//positive regulation of exocytosis;GO:0048489//synaptic vesicle transport;GO:0050766//positive regulation of phagocytosis;GO:0051875//pigment granule localization;GO:0051904//pigment granule transport;GO:0071985//multivesicular body sorting pathway;GO:0097278//complement-dependent cytotoxicity;GO:1903307//positive regulation of regulated secretory pathway;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1903435//positive regulation of constitutive secretory pathway;GO:1990182//exosomal secretion	--
ENSG00000069998	9.138	9.145	9.616	12.518	11.768	11.123	341	343	265	346	371	302	HDHD5	haloacid dehalogenase like hydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:1843]	-	-	-	-	GO:0005739//mitochondrion	-	GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000070010	19.815	21.268	22.875	20.814	19.916	20.734	492	479	421	379	409	401	UFD1	ubiquitin recognition factor in ER associated degradation 1 [Source:HGNC Symbol;Acc:HGNC:12520]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14016	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0036501//UFD1-NPL4 complex	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding	"GO:0001501//skeletal system development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0032480//negative regulation of type I interferon production;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0071712//ER-associated misfolded protein catabolic process"	--
ENSG00000070018	12.892	10.329	12.241	8.16	10.189	12.45	2514	2022	1780	1195	1609	1632	LRP6	LDL receptor related protein 6 [Source:HGNC Symbol;Acc:HGNC:6698]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: specific types;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04928//Parathyroid hormone synthesis, secretion and action"	K03068;K03068;K03068;K03068;K03068;K03068;K03068;K03068;K03068	GO:0005576//extracellular region;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043025//neuronal cell body;GO:0045121//membrane raft;GO:0045202//synapse;GO:1990851//Wnt-Frizzled-LRP5/6 complex;GO:1990909//Wnt signalosome	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0019210//kinase inhibitor activity;GO:0019534//toxin transmembrane transporter activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042813//Wnt-activated receptor activity;GO:0071936//coreceptor activity involved in Wnt signaling pathway;GO:1904928//coreceptor activity involved in canonical Wnt signaling pathway	"GO:0001933//negative regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0006897//endocytosis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0014029//neural crest formation;GO:0014033//neural crest cell differentiation;GO:0016055//Wnt signaling pathway;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0043434//response to peptide hormone;GO:0044335//canonical Wnt signaling pathway involved in neural crest cell differentiation;GO:0044340//canonical Wnt signaling pathway involved in regulation of cell proliferation;GO:0045787//positive regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060070//canonical Wnt signaling pathway;GO:0071397//cellular response to cholesterol;GO:0071542//dopaminergic neuron differentiation;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0072659//protein localization to plasma membrane;GO:0090118//receptor-mediated endocytosis involved in cholesterol transport;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0098609//cell-cell adhesion;GO:1901998//toxin transport;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation"	--
ENSG00000070019	0.025	0.012	0.017	0	0	0	2	1	1	0	0	0	GUCY2C	guanylate cyclase 2C [Source:HGNC Symbol;Acc:HGNC:4688]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K12320;K12320	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0001653//peptide receptor activity;GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0015643//toxic substance binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0016941//natriuretic peptide receptor activity;GO:0017046//peptide hormone binding	GO:0006182//cGMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0009636//response to toxic substance;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation	--
ENSG00000070031	0	0.091	0.124	0	0	0	0	1	1	0	0	0	SCT	secretin [Source:HGNC Symbol;Acc:HGNC:10607]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Digestive system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04972//Pancreatic secretion;ko04976//Bile secretion	K05263;K05263;K05263	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001664//G protein-coupled receptor binding;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0046659//digestive hormone activity;GO:0047485//protein N-terminus binding	GO:0002024//diet induced thermogenesis;GO:0007165//signal transduction;GO:0007420//brain development;GO:0009992//cellular water homeostasis;GO:0021766//hippocampus development;GO:0030157//pancreatic juice secretion;GO:0031667//response to nutrient levels;GO:0032098//regulation of appetite;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0048167//regulation of synaptic plasticity;GO:0048566//embryonic digestive tract development;GO:0050996//positive regulation of lipid catabolic process;GO:0090187//positive regulation of pancreatic juice secretion;GO:0090274//positive regulation of somatostatin secretion;GO:1903640//negative regulation of gastrin-induced gastric acid secretion	--
ENSG00000070047	10.712	10.613	12.466	11.702	11.72	11.351	1181	1189	1009	954	1097	907	PHRF1	PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:24351]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane	GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0070063//RNA polymerase binding	GO:0006366//transcription by RNA polymerase II;GO:0006397//mRNA processing	--
ENSG00000070061	19.22	18.295	17.206	13.497	17.333	16.309	1779	1754	1187	964	1300	1113	ELP1	elongator acetyltransferase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:5959]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0033588//elongator holoenzyme complex	GO:0000049//tRNA binding;GO:0005515//protein binding;GO:0043621//protein self-association	GO:0002098//tRNA wobble uridine modification;GO:0002926//tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation;GO:0006417//regulation of translation;GO:0008033//tRNA processing	--
ENSG00000070081	44.438	42.687	41.579	24.177	26.867	34.05	1507	1429	1016	589	753	744	NUCB2	nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001965//G-protein alpha-subunit binding;GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007264//small GTPase mediated signal transduction;GO:0032099//negative regulation of appetite;GO:0050790//regulation of catalytic activity	--
ENSG00000070087	68.016	76.433	69.771	68.851	67.191	65.297	2513	2855	1983	1935	2121	1818	PFN2	profilin 2 [Source:HGNC Symbol;Acc:HGNC:8882]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway	K05759;K05759;K05759;K05759;K05759	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	"GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0016887//ATP hydrolysis activity"	GO:0010633//negative regulation of epithelial cell migration;GO:0016043//cellular component organization;GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032781//positive regulation of ATPase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0044087//regulation of cellular component biogenesis;GO:0050821//protein stabilization;GO:0051496//positive regulation of stress fiber assembly;GO:0098885//modification of postsynaptic actin cytoskeleton;GO:0110053//regulation of actin filament organization;GO:1900028//negative regulation of ruffle assembly;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000070159	2.94	2.82	2.682	2.562	3.199	3.368	423	402	287	271	388	355	PTPN3	protein tyrosine phosphatase non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane	GO:0001784//phosphotyrosine residue binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017080//sodium channel regulator activity;GO:0051117//ATPase binding	GO:0000165//MAPK cascade;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0045930//negative regulation of mitotic cell cycle;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0097421//liver regeneration;GO:0098902//regulation of membrane depolarization during action potential;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000070182	0.101	0.154	0.155	0.162	0.198	0.165	14.03	22	21.64	17	18.65	17	SPTB	"spectrin beta, erythrocytic [Source:HGNC Symbol;Acc:HGNC:11274]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0009986//cell surface;GO:0014731//spectrin-associated cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0030506//ankyrin binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0051693//actin filament capping	--
ENSG00000070190	0	0	0	0	0.019	0	0	0	0	0	1	0	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides 1 [Source:HGNC Symbol;Acc:HGNC:16500]	Organismal Systems	Immune system	ko04662//B cell receptor signaling pathway	K12229	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000070193	0.116	0.316	0.043	0.064	0.078	0.043	9	14	4	6	3	4	FGF10	fibroblast growth factor 10 [Source:HGNC Symbol;Acc:HGNC:3666]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0062023//collagen-containing extracellular matrix	GO:0005104//fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity	"GO:0000132//establishment of mitotic spindle orientation;GO:0001525//angiogenesis;GO:0001656//metanephros development;GO:0001759//organ induction;GO:0001823//mesonephros development;GO:0001934//positive regulation of protein phosphorylation;GO:0001974//blood vessel remodeling;GO:0003338//metanephros morphogenesis;GO:0006935//chemotaxis;GO:0007267//cell-cell signaling;GO:0007368//determination of left/right symmetry;GO:0007431//salivary gland development;GO:0007435//salivary gland morphogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008544//epidermis development;GO:0008589//regulation of smoothened signaling pathway;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010838//positive regulation of keratinocyte proliferation;GO:0014070//response to organic cyclic compound;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0030538//embryonic genitalia morphogenesis;GO:0030855//epithelial cell differentiation;GO:0030878//thyroid gland development;GO:0030916//otic vesicle formation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031016//pancreas development;GO:0031069//hair follicle morphogenesis;GO:0031076//embryonic camera-type eye development;GO:0031532//actin cytoskeleton reorganization;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0032781//positive regulation of ATPase activity;GO:0032808//lacrimal gland development;GO:0032925//regulation of activin receptor signaling pathway;GO:0034394//protein localization to cell surface;GO:0035019//somatic stem cell population maintenance;GO:0035108//limb morphogenesis;GO:0035265//organ growth;GO:0042060//wound healing;GO:0042246//tissue regeneration;GO:0042472//inner ear morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042693//muscle cell fate commitment;GO:0043410//positive regulation of MAPK cascade;GO:0045596//negative regulation of cell differentiation;GO:0045739//positive regulation of DNA repair;GO:0045747//positive regulation of Notch signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046579//positive regulation of Ras protein signal transduction;GO:0046877//regulation of saliva secretion;GO:0048146//positive regulation of fibroblast proliferation;GO:0048286//lung alveolus development;GO:0048514//blood vessel morphogenesis;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048557//embryonic digestive tract morphogenesis;GO:0048565//digestive tract development;GO:0048566//embryonic digestive tract development;GO:0048645//animal organ formation;GO:0048730//epidermis morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048807//female genitalia morphogenesis;GO:0048808//male genitalia morphogenesis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050673//epithelial cell proliferation;GO:0050674//urothelial cell proliferation;GO:0050677//positive regulation of urothelial cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050872//white fat cell differentiation;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051145//smooth muscle cell differentiation;GO:0051549//positive regulation of keratinocyte migration;GO:0060019//radial glial cell differentiation;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060173//limb development;GO:0060174//limb bud formation;GO:0060425//lung morphogenesis;GO:0060428//lung epithelium development;GO:0060430//lung saccule development;GO:0060436//bronchiole morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060447//bud outgrowth involved in lung branching;GO:0060449//bud elongation involved in lung branching;GO:0060496//mesenchymal-epithelial cell signaling involved in lung development;GO:0060510//type II pneumocyte differentiation;GO:0060513//prostatic bud formation;GO:0060541//respiratory system development;GO:0060594//mammary gland specification;GO:0060595//fibroblast growth factor receptor signaling pathway involved in mammary gland specification;GO:0060615//mammary gland bud formation;GO:0060661//submandibular salivary gland formation;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0060667//branch elongation involved in salivary gland morphogenesis;GO:0060879//semicircular canal fusion;GO:0060915//mesenchymal cell differentiation involved in lung development;GO:0061033//secretion by lung epithelial cell involved in lung growth;GO:0061115//lung proximal/distal axis specification;GO:0070075//tear secretion;GO:0070352//positive regulation of white fat cell proliferation;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070384//Harderian gland development;GO:0071338//positive regulation of hair follicle cell proliferation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000070214	15.232	14.988	13.231	11.709	14.657	12.34	1700	1599	1066	896	1215	1019	SLC44A1	solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K06515	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0015220//choline transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0015871//choline transport;GO:0042426//choline catabolic process;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000070269	13.74	10.779	10.132	9.112	11.245	11.445	1017	916	634	585	794	704	TMEM260	transmembrane protein 260 [Source:HGNC Symbol;Acc:HGNC:20185]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000070366	11.268	11.792	12.041	10.93	11.224	10.57	1396.2	1468.68	1083.59	958.97	1154.3	952.96	SMG6	SMG6 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:17809]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K11124	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035145//exon-exon junction complex"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042162//telomeric DNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0046872//metal ion binding;GO:0070034//telomerase RNA binding;GO:0070182//DNA polymerase binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006406//mRNA export from nucleus;GO:0032204//regulation of telomere maintenance;GO:0032210//regulation of telomere maintenance via telomerase;GO:0035303//regulation of dephosphorylation;GO:0051972//regulation of telomerase activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1904354//negative regulation of telomere capping"	--
ENSG00000070367	20.479	12.929	14.256	11.043	13.032	13.204	1930	1193	1037	728	952	889	EXOC5	exocyst complex component 5 [Source:HGNC Symbol;Acc:HGNC:10696]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K19984	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030496//midbody	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0047485//protein N-terminus binding	GO:0000281//mitotic cytokinesis;GO:0001736//establishment of planar polarity;GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0072659//protein localization to plasma membrane;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis;GO:1904019//epithelial cell apoptotic process;GO:1905515//non-motile cilium assembly	--
ENSG00000070371	1.477	1.929	2.202	1.458	1.709	2.098	168	173	131	118	164	117	CLTCL1	clathrin heavy chain like 1 [Source:HGNC Symbol;Acc:HGNC:2093]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Transport and catabolism;Infectious disease: bacterial;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04142//Lysosome;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K04646;K04646;K04646;K04646;K04646;K04646	GO:0005770//late endosome;GO:0005802//trans-Golgi network;GO:0005819//spindle;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit;GO:0030135//coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045334//clathrin-coated endocytic vesicle;GO:0070062//extracellular exosome;GO:0071439//clathrin complex;GO:0097443//sorting endosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0032051//clathrin light chain binding	"GO:0000278//mitotic cell cycle;GO:0006886//intracellular protein transport;GO:0006898//receptor-mediated endocytosis;GO:0009653//anatomical structure morphogenesis;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0046326//positive regulation of glucose import;GO:0046907//intracellular transport"	--
ENSG00000070388	0	0.074	0.152	0.196	0.044	0.103	0	2	3	4	1	2	FGF22	fibroblast growth factor 22 [Source:HGNC Symbol;Acc:HGNC:3679]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration	--
ENSG00000070404	32.555	40.623	27.149	35.413	34.36	33.431	1523	1909	984	1171	1387	1088	FSTL3	follistatin like 3 [Source:HGNC Symbol;Acc:HGNC:3973]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005788//endoplasmic reticulum lumen	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0048185//activin binding	GO:0001503//ossification;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0022409//positive regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030510//regulation of BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0045671//negative regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	--
ENSG00000070413	35.226	37.695	37.911	40.482	41.402	40.402	3256	3504	2587	2770	3228	2712	DGCR2	DiGeorge syndrome critical region gene 2 [Source:HGNC Symbol;Acc:HGNC:2845]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis;GO:0050890//cognition	--
ENSG00000070423	9.013	10.713	10.019	10.085	9.357	12.402	299	338	242	239	252	301	RNF126	ring finger protein 126 [Source:HGNC Symbol;Acc:HGNC:21151]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042147//retrograde transport, endosome to Golgi;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0071629//cytoplasm protein quality control by the ubiquitin-proteasome system"	--
ENSG00000070444	3.221	3.555	2.889	3.727	3.383	3	329	365	218	282	292	223	MNT	MAX network transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:7188]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007569//cell aging;GO:0008285//negative regulation of cell population proliferation;GO:0051726//regulation of cell cycle;GO:2001234//negative regulation of apoptotic signaling pathway"	bHLH
ENSG00000070476	6.892	6.469	7.724	6.491	7.036	6.673	412	377	332	281	350	290	ZXDC	ZXD family zinc finger C [Source:HGNC Symbol;Acc:HGNC:28160]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030275//LRR domain binding;GO:0046872//metal ion binding;GO:0070742//C2H2 zinc finger domain binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000070495	6.314	6.81	7.929	5.655	6.099	8.026	284	291	239	187	231	249	JMJD6	"jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0032451//demethylase activity;GO:0032452//histone demethylase activity;GO:0033746//histone H3-methyl-arginine-2 demethylase activity;GO:0033749//histone H3-methyl-arginine-3 demethylase activity;GO:0035515//oxidative RNA demethylase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0070815//peptidyl-lysine 5-dioxygenase activity;GO:0106140//P-TEFb complex binding;GO:0140537//transcription regulator activator activity	"GO:0001568//blood vessel development;GO:0001822//kidney development;GO:0002040//sprouting angiogenesis;GO:0006325//chromatin organization;GO:0006397//mRNA processing;GO:0006482//protein demethylation;GO:0006909//phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0007507//heart development;GO:0008380//RNA splicing;GO:0018395//peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0033077//T cell differentiation in thymus;GO:0035513//oxidative RNA demethylation;GO:0042116//macrophage activation;GO:0043277//apoptotic cell clearance;GO:0043654//recognition of apoptotic cell;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0048821//erythrocyte development;GO:0051260//protein homooligomerization;GO:0060041//retina development in camera-type eye;GO:0070078//histone H3-R2 demethylation;GO:0070079//histone H4-R3 demethylation"	--
ENSG00000070501	10.731	8.959	10.742	8.031	7.016	8.054	207	173	150	129	116	120	POLB	DNA polymerase beta [Source:HGNC Symbol;Acc:HGNC:9174]	Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Cancer: overview;Replication and repair	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko03410//Base excision repair	K02330;K02330;K02330	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016829//lyase activity;GO:0019899//enzyme binding;GO:0034061//DNA polymerase activity;GO:0046872//metal ion binding	"GO:0001701//in utero embryonic development;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006286//base-excision repair, base-free sugar-phosphate removal;GO:0006287//base-excision repair, gap-filling;GO:0006290//pyrimidine dimer repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007435//salivary gland morphogenesis;GO:0007568//aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010332//response to gamma radiation;GO:0016445//somatic diversification of immunoglobulins;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0045471//response to ethanol;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0048872//homeostasis of number of cells;GO:0051402//neuron apoptotic process;GO:0055093//response to hyperoxia;GO:0071707//immunoglobulin heavy chain V-D-J recombination;GO:0071897//DNA biosynthetic process"	--
ENSG00000070526	0	0	0	0	0	0	0	0	0	0	0	0	ST6GALNAC1	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23614]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K03479;K03479	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006486//protein glycosylation;GO:0009312//oligosaccharide biosynthetic process;GO:0097503//sialylation	--
ENSG00000070540	11.374	11.734	11.381	8.841	9.497	8.748	397.9	407.28	249.57	244.89	279.61	222.87	WIPI1	"WD repeat domain, phosphoinositide interacting 1 [Source:HGNC Symbol;Acc:HGNC:25471]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04136//Autophagy - other	K17908;K17908;K17908;K17908;K17908;K17908;K17908;K17908	GO:0000139//Golgi membrane;GO:0000407//phagophore assembly site;GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0034045//phagophore assembly site membrane	"GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030331//estrogen receptor binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0050681//androgen receptor binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	"GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0034497//protein localization to phagophore assembly site;GO:0044804//autophagy of nucleus;GO:0048203//vesicle targeting, trans-Golgi to endosome;GO:2000786//positive regulation of autophagosome assembly"	--
ENSG00000070601	0.509	0.593	0.416	0.882	0.751	0.713	53	62	32	68	66	54	FRMPD1	FERM and PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29159]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0090150//establishment of protein localization to membrane	--
ENSG00000070610	26.025	25.537	29.327	30.518	30.455	32.513	1802	1770	1502	1591	1796	1640	GBA2	glucosylceramidase beta 2 [Source:HGNC Symbol;Acc:HGNC:18986]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K17108;K17108;K17108	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019898//extrinsic component of membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0090498//extrinsic component of Golgi membrane	"GO:0004348//glucosylceramidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0008422//beta-glucosidase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046527//glucosyltransferase activity;GO:0050295//steryl-beta-glucosidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006680//glucosylceramide catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0007417//central nervous system development;GO:0008152//metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008206//bile acid metabolic process;GO:0016139//glycoside catabolic process;GO:0021954//central nervous system neuron development;GO:0030259//lipid glycosylation;GO:0030833//regulation of actin filament polymerization;GO:0031113//regulation of microtubule polymerization;GO:0097035//regulation of membrane lipid distribution	--
ENSG00000070614	34.488	35.528	35.492	40.827	40.653	40.061	4862	5228	3543	4339	5086	4081	NDST1	N-deacetylase and N-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:7680]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02576;K02576	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0050119//N-acetylglucosamine deacetylase activity;GO:0102140//heparan sulfate N-deacetylase activity	"GO:0000271//polysaccharide biosynthetic process;GO:0003279//cardiac septum development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006477//protein sulfation;GO:0006954//inflammatory response;GO:0007507//heart development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008152//metabolic process;GO:0008283//cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030210//heparin biosynthetic process;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0035904//aorta development;GO:0043410//positive regulation of MAPK cascade;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048702//embryonic neurocranium morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0060976//coronary vasculature development;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process"	--
ENSG00000070669	9.48	7.746	5.524	6.047	6.034	14.033	292	274	166	181	192	387	ASNS	asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:HGNC:753]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism"	K01953;K01953;K01953	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006529//asparagine biosynthetic process;GO:0006541//glutamine metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0042149//cellular response to glucose starvation;GO:0043066//negative regulation of apoptotic process;GO:0045931//positive regulation of mitotic cell cycle;GO:0070981//L-asparagine biosynthetic process	--
ENSG00000070718	7.001	7.206	5.932	4.881	5.646	6.913	486	453	311	262	348	344	AP3M2	adaptor related protein complex 3 subunit mu 2 [Source:HGNC Symbol;Acc:HGNC:570]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12398	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030119//AP-type membrane coat adaptor complex;GO:0030123//AP-3 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:1904115//axon cytoplasm	GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016183//synaptic vesicle coating;GO:0016192//vesicle-mediated transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0036465//synaptic vesicle recycling;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport"	--
ENSG00000070729	0.03	0	0	0	0.013	0	1	0	0	0	1	0	CNGB1	cyclic nucleotide gated channel subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:2151]	Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Sensory system;Signal transduction;Signal transduction;Sensory system	ko04740//Olfactory transduction;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04744//Phototransduction	K04952;K04952;K04952;K04952	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0060170//ciliary membrane;GO:1902495//transmembrane transporter complex	GO:0000166//nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0043855//cyclic nucleotide-gated ion channel activity	"GO:0001895//retina homeostasis;GO:0006811//ion transport;GO:0006812//cation transport;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007608//sensory perception of smell;GO:0010628//positive regulation of gene expression;GO:0021630//olfactory nerve maturation;GO:0033365//protein localization to organelle;GO:0035845//photoreceptor cell outer segment organization;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0051899//membrane depolarization;GO:0098655//cation transmembrane transport;GO:0099105//ion channel modulating, G protein-coupled receptor signaling pathway;GO:1990834//response to odorant"	--
ENSG00000070731	119.421	126.123	129.288	115.586	115.835	117.814	3705.07	3956.17	3055.86	2736.14	3054.01	2665.11	ST6GALNAC2	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10867]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K06616;K06616	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0019082//viral protein processing;GO:0097503//sialylation;GO:1990743//protein sialylation	--
ENSG00000070748	0.182	0.181	0.051	0.049	0.166	0.031	20	20	2	4	7	1	CHAT	choline O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:1912]	Organismal Systems;Metabolism	Nervous system;Lipid metabolism	ko04725//Cholinergic synapse;ko00564//Glycerophospholipid metabolism	K00623;K00623	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004102//choline O-acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0006836//neurotransmitter transport;GO:0007274//neuromuscular synaptic transmission;GO:0008292//acetylcholine biosynthetic process;GO:0042136//neurotransmitter biosynthetic process	--
ENSG00000070756	191.167	185.323	165.93	189.173	185.087	180.083	10926	10693	7010	7819	8846	7443.98	PABPC1	poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031252//cell leading edge;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0106002//mCRD-mediated mRNA stability complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding;GO:0008494//translation activator activity	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000398//mRNA splicing, via spliceosome;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0031047//gene silencing by RNA;GO:0045070//positive regulation of viral genome replication;GO:0048255//mRNA stabilization;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0070934//CRD-mediated mRNA stabilization;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000070759	1.884	1.921	2.581	1.211	1.728	2.589	120	123	121.41	57.15	93	120	TESK2	testis associated actin remodelling kinase 2 [Source:HGNC Symbol;Acc:HGNC:11732]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0048041//focal adhesion assembly	--
ENSG00000070761	23.501	26.146	28.988	27.589	25.971	29.793	606	685	514	543	583	527	CFAP20	cilia and flagella associated protein 20 [Source:HGNC Symbol;Acc:HGNC:29523]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007275//multicellular organism development;GO:0018095//protein polyglutamylation;GO:0060271//cilium assembly;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:2000147//positive regulation of cell motility;GO:2000253//positive regulation of feeding behavior	--
ENSG00000070770	11.676	11.562	10.61	12.521	10.35	10.789	457	441	291	363	339	280	CSNK2A2	casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Translation;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05020//Prion disease;ko04064//NF-kappa B signaling pathway;ko04310//Wnt signaling pathway;ko05162//Measles;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko03008//Ribosome biogenesis in eukaryotes;ko04137//Mitophagy - animal;ko04520//Adherens junction	K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097	GO:0000785//chromatin;GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005956//protein kinase CK2 complex;GO:0031519//PcG protein complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0047485//protein N-terminus binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0021987//cerebral cortex development;GO:0051726//regulation of cell cycle;GO:0097421//liver regeneration;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1905818//regulation of chromosome separation;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000070778	9.928	8.699	9.541	7.7	8.534	8.83	1276	1099	844	746	938	804	PTPN21	protein tyrosine phosphatase non-receptor type 21 [Source:HGNC Symbol;Acc:HGNC:9651]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000070785	8.845	8.133	9.416	7.549	6.824	7.54	295	275	234	189	189	185	EIF2B3	eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K03241	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0032045//guanyl-nucleotide exchange factor complex	"GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0016779//nucleotidyltransferase activity"	GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0009058//biosynthetic process;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0014003//oligodendrocyte development;GO:0043434//response to peptide hormone;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000070808	0.218	0.139	0.239	0.266	0.215	0.126	19	14	14	14	15	8	CAMK2A	calcium/calmodulin dependent protein kinase II alpha [Source:HGNC Symbol;Acc:HGNC:1460]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Development and regeneration;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Circulatory system;Cell growth and death;Nervous system;Nervous system;Signal transduction;Nervous system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Endocrine system;Endocrine system;Endocrine system;Signal transduction;Cancer: specific types;Digestive system;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04217//Necroptosis;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko05214//Glioma;ko04971//Gastric acid secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043226//organelle;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035254//glutamate receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0038166//angiotensin-activated signaling pathway;GO:0046777//protein autophosphorylation;GO:0046928//regulation of neurotransmitter secretion;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051346//negative regulation of hydrolase activity;GO:0051928//positive regulation of calcium ion transport;GO:0060996//dendritic spine development;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1990443//peptidyl-threonine autophosphorylation;GO:2000124//regulation of endocannabinoid signaling pathway;GO:2001222//regulation of neuron migration	--
ENSG00000070814	8.809	8.53	8.429	8.115	9.081	7.065	797	857	570	579	727	494	TCOF1	treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14562	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046982//protein heterodimerization activity;GO:0097110//scaffold protein binding	GO:0001501//skeletal system development;GO:0006417//regulation of translation;GO:0014029//neural crest formation;GO:0014032//neural crest cell development;GO:0042790//nucleolar large rRNA transcription by RNA polymerase I	--
ENSG00000070831	32.805	32.971	30.304	27.839	32.693	30.595	1445.26	1466.96	989.95	934.8	1219.35	976.64	CDC42	cell division cycle 42 [Source:HGNC Symbol;Acc:HGNC:1736]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Development and regeneration;Cellular community - eukaryotes;Immune system;Endocrine and metabolic disease;Nervous system;Immune system;Immune system;Endocrine and metabolic disease;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Infectious disease: bacterial;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko04932//Non-alcoholic fatty liver disease;ko04722//Neurotrophin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04912//GnRH signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05211//Renal cell carcinoma;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway	K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393	GO:0000139//Golgi membrane;GO:0000322//storage vacuole;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0030141//secretory granule;GO:0030175//filopodium;GO:0030425//dendrite;GO:0030496//midbody;GO:0031252//cell leading edge;GO:0031256//leading edge membrane;GO:0032991//protein-containing complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043227//membrane-bounded organelle;GO:0045177//apical part of cell;GO:0045335//phagocytic vesicle;GO:0051233//spindle midzone;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0072686//mitotic spindle;GO:0098685//Schaffer collateral - CA1 synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0030742//GTP-dependent protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0031996//thioesterase binding;GO:0032427//GBD domain binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0042802//identical protein binding;GO:0061630//ubiquitin protein ligase activity	"GO:0002040//sprouting angiogenesis;GO:0003161//cardiac conduction system development;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007030//Golgi organization;GO:0007088//regulation of mitotic nuclear division;GO:0007097//nuclear migration;GO:0007163//establishment or maintenance of cell polarity;GO:0007229//integrin-mediated signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0010591//regulation of lamellipodium assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0021762//substantia nigra development;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0030225//macrophage differentiation;GO:0030307//positive regulation of cell growth;GO:0031274//positive regulation of pseudopodium assembly;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032467//positive regulation of cytokinesis;GO:0032488//Cdc42 protein signal transduction;GO:0034329//cell junction assembly;GO:0034332//adherens junction organization;GO:0034613//cellular protein localization;GO:0035050//embryonic heart tube development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0036336//dendritic cell migration;GO:0038189//neuropilin signaling pathway;GO:0039694//viral RNA genome replication;GO:0043085//positive regulation of catalytic activity;GO:0043393//regulation of protein binding;GO:0043410//positive regulation of MAPK cascade;GO:0043525//positive regulation of neuron apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045740//positive regulation of DNA replication;GO:0046330//positive regulation of JNK cascade;GO:0046847//filopodium assembly;GO:0048549//positive regulation of pinocytosis;GO:0048664//neuron fate determination;GO:0051130//positive regulation of cellular component organization;GO:0051301//cell division;GO:0051489//regulation of filopodium assembly;GO:0051491//positive regulation of filopodium assembly;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051647//nucleus localization;GO:0051683//establishment of Golgi localization;GO:0051835//positive regulation of synapse structural plasticity;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0060047//heart contraction;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0060661//submandibular salivary gland formation;GO:0060997//dendritic spine morphogenesis;GO:0071346//cellular response to interferon-gamma;GO:0072384//organelle transport along microtubule;GO:0086101//endothelin receptor signaling pathway involved in heart process;GO:0090135//actin filament branching;GO:0090316//positive regulation of intracellular protein transport;GO:0099159//regulation of modification of postsynaptic structure;GO:0099563//modification of synaptic structure;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:2000251//positive regulation of actin cytoskeleton reorganization"	--
ENSG00000070882	2.219	1.941	2.261	2.848	2.18	2.804	253	226	191	220	218	229	OSBPL3	oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0015918//sterol transport	--
ENSG00000070886	0.054	0	0	0	0	0	2	0	0	0	0	0	EPHA8	EPH receptor A8 [Source:HGNC Symbol;Acc:HGNC:3391]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05109	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding	GO:0006468//protein phosphorylation;GO:0006929//substrate-dependent cell migration;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0016310//phosphorylation;GO:0016322//neuron remodeling;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030155//regulation of cell adhesion;GO:0031175//neuron projection development;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0033674//positive regulation of kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0071372//cellular response to follicle-stimulating hormone stimulus	--
ENSG00000070915	0.015	0.046	0.012	0.062	0.056	0.079	1	3	1	4	4	5	SLC12A3	solute carrier family 12 member 3 [Source:HGNC Symbol;Acc:HGNC:10912]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008511//sodium:potassium:chloride symporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015378//sodium:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006884//cell volume homeostasis;GO:0015698//inorganic anion transport;GO:0035725//sodium ion transmembrane transport;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000070950	1.585	2.329	1.745	2.138	1.833	2.063	187	147	95	107	96	92	RAD18	RAD18 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:18278]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0035861//site of double-strand break;GO:0042405//nuclear inclusion body;GO:0097505//Rad6-Rad18 complex	GO:0000403//Y-form DNA binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0051984//positive regulation of chromosome segregation;GO:0060548//negative regulation of cell death	--
ENSG00000070961	9.739	8.945	8.799	6.105	11.423	9.639	869	661	457	452	593	678	ATP2B1	ATPase plasma membrane Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:814]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Digestive system;Endocrine system;Digestive system;Digestive system;Excretory system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04972//Pancreatic secretion;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850	GO:0001772//immunological synapse;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032590//dendrite membrane;GO:0032591//dendritic spine membrane;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0015085//calcium ion transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0046872//metal ion binding;GO:1905056//P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	GO:0001818//negative regulation of cytokine production;GO:0003056//regulation of vascular associated smooth muscle contraction;GO:0003407//neural retina development;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007420//brain development;GO:0007568//aging;GO:0008217//regulation of blood pressure;GO:0009409//response to cold;GO:0030501//positive regulation of bone mineralization;GO:0034220//ion transmembrane transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051928//positive regulation of calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:0071305//cellular response to vitamin D;GO:0071386//cellular response to corticosterone stimulus;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1900076//regulation of cellular response to insulin stimulus;GO:1901660//calcium ion export;GO:1903779//regulation of cardiac conduction;GO:1990034//calcium ion export across plasma membrane	--
ENSG00000070985	0	0	0	0.018	0.015	0	0	0	0	1	1	0	TRPM5	transient receptor potential cation channel subfamily M member 5 [Source:HGNC Symbol;Acc:HGNC:14323]	Organismal Systems	Sensory system	ko04742//Taste transduction	K04980	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0099604//ligand-gated calcium channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0019722//calcium-mediated signaling;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0050909//sensory perception of taste;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000071051	22.712	20.755	21.256	20.335	21.741	23.848	1071	949	804	754	965	899	NCK2	NCK adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:7665]	Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing	Infectious disease: bacterial;Development and regeneration;Immune system;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway	K19862;K19862;K19862;K19862	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0012506//vesicle membrane;GO:0014069//postsynaptic density;GO:0045202//synapse	GO:0001784//phosphotyrosine residue binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0030159//signaling receptor complex adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity;GO:0044877//protein-containing complex binding;GO:0097110//scaffold protein binding	GO:0001771//immunological synapse formation;GO:0006417//regulation of translation;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0007172//signal complex assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0008285//negative regulation of cell population proliferation;GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0036493//positive regulation of translation in response to endoplasmic reticulum stress;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048013//ephrin receptor signaling pathway;GO:0051016//barbed-end actin filament capping;GO:0051017//actin filament bundle assembly;GO:0060996//dendritic spine development;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	--
ENSG00000071054	44.267	42.338	40.245	31.547	35.531	36.032	5055	4862	3446	2640	3341	2920	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6866]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04407	GO:0005737//cytoplasm;GO:0005925//focal adhesion	GO:0000166//nucleotide binding;GO:0004111//creatine kinase activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001953//negative regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030335//positive regulation of cell migration;GO:0032014//positive regulation of ARF protein signal transduction;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0043547//positive regulation of GTPase activity;GO:0046328//regulation of JNK cascade;GO:0048812//neuron projection morphogenesis;GO:0051549//positive regulation of keratinocyte migration;GO:0051894//positive regulation of focal adhesion assembly;GO:0120183//positive regulation of focal adhesion disassembly	--
ENSG00000071073	4.538	4.295	5.17	3.485	4.562	5.169	696	536	393.15	385	494	475	MGAT4A	"alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A [Source:HGNC Symbol;Acc:HGNC:7047]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K00738;K00738;K00738	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005777//peroxisome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0008375//acetylglucosaminyltransferase activity;GO:0008453//alanine-glyoxylate transaminase activity;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006491//N-glycan processing;GO:0019082//viral protein processing;GO:0046487//glyoxylate metabolic process;GO:0090284//positive regulation of protein glycosylation in Golgi	--
ENSG00000071082	341.116	347.413	338.374	331.462	253.978	289.397	3433	3500	2584	2476	2263	2242	RPL31	ribosomal protein L31 [Source:HGNC Symbol;Acc:HGNC:10334]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02910;K02910	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000071127	160.998	157.332	172.396	157.424	165.307	169.89	8299	8289	6956	6440	7388	6420	WDR1	WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754]	-	-	-	-	GO:0002102//podosome;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0002446//neutrophil mediated immunity;GO:0007605//sensory perception of sound;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0030042//actin filament depolymerization;GO:0030043//actin filament fragmentation;GO:0030220//platelet formation;GO:0030834//regulation of actin filament depolymerization;GO:0030836//positive regulation of actin filament depolymerization;GO:0030865//cortical cytoskeleton organization;GO:0040011//locomotion;GO:0042247//establishment of planar polarity of follicular epithelium;GO:0043297//apical junction assembly;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0045214//sarcomere organization;GO:0048713//regulation of oligodendrocyte differentiation;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:1990266//neutrophil migration	--
ENSG00000071189	11.487	7.253	7.832	6.126	7.487	8.581	1175	799	616	499	621	632	SNX13	sorting nexin 13 [Source:HGNC Symbol;Acc:HGNC:21335]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding	GO:0006886//intracellular protein transport;GO:0009968//negative regulation of signal transduction;GO:0015031//protein transport;GO:0043547//positive regulation of GTPase activity	--
ENSG00000071203	0	0	0	0.064	0	0	0	0	0	1	0	0	MS4A12	membrane spanning 4-domains A12 [Source:HGNC Symbol;Acc:HGNC:13370]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000071205	2.944	2.851	2.485	2.442	2.35	1.993	194	184	116	112	121	94	ARHGAP10	Rho GTPase activating protein 10 [Source:HGNC Symbol;Acc:HGNC:26099]	Human Diseases	Infectious disease: bacterial	ko05100//Bacterial invasion of epithelial cells	K13736	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000071242	14.882	11.493	14.871	15.894	10.234	14.127	1372	1296	936	829	1019	870	RPS6KA2	ribosomal protein S6 kinase A2 [Source:HGNC Symbol;Acc:HGNC:10431]	Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Environmental adaptation;Infectious disease: bacterial;Cancer: overview;Signal transduction;Cell growth and death;Nervous system;Endocrine system;Endocrine and metabolic disease;Nervous system	ko04010//MAPK signaling pathway;ko04714//Thermogenesis;ko05135//Yersinia infection;ko05207//Chemical carcinogenesis - receptor activation;ko04150//mTOR signaling pathway;ko04114//Oocyte meiosis;ko04722//Neurotrophin signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko04720//Long-term potentiation	K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005840//ribosome;GO:0045202//synapse;GO:0072687//meiotic spindle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001556//oocyte maturation;GO:0002035//brain renin-angiotensin system;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010659//cardiac muscle cell apoptotic process;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0045786//negative regulation of cell cycle;GO:0045835//negative regulation of meiotic nuclear division;GO:0060047//heart contraction;GO:0070613//regulation of protein processing;GO:0071322//cellular response to carbohydrate stimulus	--
ENSG00000071243	6.916	6.134	4.913	5.48	5.32	7.478	219	212	139	128	166	187	ING3	inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032777//Piccolo NuA4 histone acetyltransferase complex;GO:0035267//NuA4 histone acetyltransferase complex	GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000071246	13.51	12.229	12.474	12.84	12.447	11.929	1708	1579	1220	1258	1392	1161	VASH1	vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0045177//apical part of cell	GO:0003779//actin binding;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006508//proteolysis;GO:0007049//cell cycle;GO:0009611//response to wounding;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0060674//placenta blood vessel development;GO:0060716//labyrinthine layer blood vessel development;GO:1901491//negative regulation of lymphangiogenesis;GO:2000772//regulation of cellular senescence	--
ENSG00000071282	9.039	10.313	9.7	9.135	9.505	7.079	284	313	206	212	261	152	LMCD1	LIM and cysteine rich domains 1 [Source:HGNC Symbol;Acc:HGNC:6633]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0110165//cellular anatomical entity	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010611//regulation of cardiac muscle hypertrophy;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000071462	26.003	24.537	26.346	35.254	30.865	24.232	609	594	469	625	592	432	BUD23	BUD23 rRNA methyltransferase and ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:16405]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0016740//transferase activity;GO:0046982//protein heterodimerization activity	GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0032259//methylation;GO:0042254//ribosome biogenesis;GO:0070476//rRNA (guanine-N7)-methylation;GO:2000234//positive regulation of rRNA processing	--
ENSG00000071537	16.881	15.035	12.67	11.601	12.456	12.099	2433	2111	1468	1358	1644	1446	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:10717]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14026	GO:0000836//Hrd1p ubiquitin ligase complex;GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex	GO:0005515//protein binding	"GO:0006641//triglyceride metabolic process;GO:0007219//Notch signaling pathway;GO:0009306//protein secretion;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0034976//response to endoplasmic reticulum stress;GO:0036503//ERAD pathway;GO:0050821//protein stabilization"	--
ENSG00000071539	0.932	1.069	1.396	1.197	1.019	0.896	47	45	52	29	36	31	TRIP13	thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307]	-	-	-	-	GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005694//chromosome	GO:0000166//nucleotide binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	"GO:0001556//oocyte maturation;GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0051598//meiotic recombination checkpoint signaling"	--
ENSG00000071553	138.553	142.353	147.997	178.201	176.081	154.093	5599	5779.04	4299	5235	5716	4571	ATP6AP1	ATPase H+ transporting accessory protein 1 [Source:HGNC Symbol;Acc:HGNC:868]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Metabolism;Cellular Processes;Human Diseases;Human Diseases	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Immune disease;Energy metabolism;Transport and catabolism;Infectious disease: bacterial;Infectious disease: bacterial	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection	K03662;K03662;K03662;K03662;K03662;K03662;K03662;K03662;K03662;K03662	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031267//small GTPase binding	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0030641//regulation of cellular pH;GO:0036035//osteoclast development;GO:0036295//cellular response to increased oxygen levels;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:0099638//endosome to plasma membrane protein transport;GO:1902600//proton transmembrane transport	--
ENSG00000071564	22.076	21.258	18.893	19.417	20.628	23.904	1242	1265	912	833	1005	1044	TCF3	transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11633]	Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Infectious disease: viral;Cellular community - eukaryotes	ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko04550//Signaling pathways regulating pluripotency of stem cells	K09063;K09063;K09063	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070644//vitamin D response element binding;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002326//B cell lineage commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0033152//immunoglobulin V(D)J recombination;GO:0045666//positive regulation of neuron differentiation;GO:0045787//positive regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	bHLH
ENSG00000071575	16.097	15.929	18.302	16.835	18.088	16.417	1292	1245	1021	976	1205	937	TRIB2	tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0004672//protein kinase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032693//negative regulation of interleukin-10 production;GO:0043405//regulation of MAP kinase activity;GO:0045599//negative regulation of fat cell differentiation	--
ENSG00000071626	24.013	25.162	24.581	27.198	24.769	28.057	1080	1138	817	907	941	920	DAZAP1	DAZ associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2683]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14411	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0034046//poly(G) binding;GO:0035613//RNA stem-loop binding	"GO:0001893//maternal placenta development;GO:0007283//spermatogenesis;GO:0008283//cell population proliferation;GO:0030154//cell differentiation;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000071655	31.428	31.091	30.697	37.679	36.026	36.767	1861.74	1828.16	1370	1653.59	1802.19	1625.94	MBD3	methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918]	-	-	-	-	GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0031492//nucleosomal DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006338//chromatin remodeling;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0007420//brain development;GO:0007507//heart development;GO:0007568//aging;GO:0009888//tissue development;GO:0014070//response to organic cyclic compound;GO:0016573//histone acetylation;GO:0016575//histone deacetylation;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0042659//regulation of cell fate specification;GO:0044030//regulation of DNA methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048568//embryonic organ development;GO:2000736//regulation of stem cell differentiation"	MBD
ENSG00000071677	0	0	0	0	0	0	0	0	0	0	0	0	PRLH	prolactin releasing hormone [Source:HGNC Symbol;Acc:HGNC:17945]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05269	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0031861//prolactin-releasing peptide receptor binding	GO:0001894//tissue homeostasis;GO:0002021//response to dietary excess;GO:0002023//reduction of food intake in response to dietary excess;GO:0006112//energy reserve metabolic process;GO:0006629//lipid metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007631//feeding behavior;GO:0009749//response to glucose;GO:0032868//response to insulin;GO:0040014//regulation of multicellular organism growth;GO:0042755//eating behavior;GO:0043434//response to peptide hormone;GO:0045444//fat cell differentiation;GO:0048483//autonomic nervous system development	--
ENSG00000071794	13.73	9.453	9.26	6.646	9.671	9.675	1375.39	936.27	676.86	490.48	771.89	658.73	HLTF	helicase like transcription factor [Source:HGNC Symbol;Acc:HGNC:11099]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0043233//organelle lumen;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0140658//ATP-dependent chromatin remodeler activity"	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0008152//metabolic process;GO:0016567//protein ubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis	--
ENSG00000071859	30.44	28.461	28.442	28.715	27.01	28.676	843	793	582	589	632	578	FAM50A	family with sequence similarity 50 member A [Source:HGNC Symbol;Acc:HGNC:18786]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006325//chromatin organization;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing	--
ENSG00000071889	24.884	28.925	24.289	28.438	30.908	27.428	695	856	609	651	747	572	FAM3A	FAM3 metabolism regulating signaling molecule A [Source:HGNC Symbol;Acc:HGNC:13749]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0019732//antifungal humoral response;GO:0045721//negative regulation of gluconeogenesis;GO:0046890//regulation of lipid biosynthetic process;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1905035//negative regulation of antifungal innate immune response	--
ENSG00000071894	17.297	16.979	18.248	17.511	17.789	17.066	1606	1585	1251	1204	1396	1153	CPSF1	cleavage and polyadenylation specific factor 1 [Source:HGNC Symbol;Acc:HGNC:2324]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14401	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000071909	0.097	0	0.02	0	0.034	0	11	0	1	0	2	0	MYO3B	myosin IIIB [Source:HGNC Symbol;Acc:HGNC:15576]	Organismal Systems	Sensory system	ko04745//Phototransduction - fly	K08834	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016459//myosin complex;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0043226//organelle	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0016310//phosphorylation;GO:0050896//response to stimulus;GO:0090103//cochlea morphogenesis	--
ENSG00000071967	90.608	80.991	93.604	91.268	87.802	97.342	7932	7041	6013	5834	6469	6157	CYBRD1	cytochrome b reductase 1 [Source:HGNC Symbol;Acc:HGNC:20797]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K08370	GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016722//oxidoreductase activity, acting on metal ions;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0140571//transmembrane ascorbate ferrireductase activity;GO:0140575//transmembrane monodehydroascorbate reductase activity"	GO:0006879//cellular iron ion homeostasis;GO:0010039//response to iron ion;GO:0033215//reductive iron assimilation;GO:0055072//iron ion homeostasis;GO:0055085//transmembrane transport;GO:0140576//ascorbate homeostasis	--
ENSG00000071991	21.582	17.974	13.094	8.495	10.065	7.881	1682	1315	746	481	642	485	CDH19	cadherin 19 [Source:HGNC Symbol;Acc:HGNC:1758]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000071994	24.453	26.668	29.756	24.748	21.439	29.162	797	848	651	563	572	632	PDCD2	programmed cell death 2 [Source:HGNC Symbol;Acc:HGNC:8762]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:1901532//regulation of hematopoietic progenitor cell differentiation;GO:1902035//positive regulation of hematopoietic stem cell proliferation	--
ENSG00000072041	21.424	21.068	18.84	15.207	16.972	18.782	1641	1588	1082	861	1095	1109	SLC6A15	solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005298//proline:sodium symporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport;GO:0015820//leucine transport;GO:0015824//proline transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:1903825//organic acid transmembrane transport	--
ENSG00000072042	123.107	111.866	108.533	86.497	99.506	104.984	5893	5287	3870	3160	3930	3718	RDH11	retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11152;K11152	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650//NADP-retinol dehydrogenase activity;GO:0102354//11-cis-retinol dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0110095//cellular detoxification of aldehyde	--
ENSG00000072062	31.112	32.7	30.758	30.052	32.107	27.247	1547	1586	1151	1168	1399	1104	PRKACA	protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]	Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Sensory system;Infectious disease: viral;Signal transduction;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Cancer: overview;Immune system;Substance dependence;Cellular community - eukaryotes;Infectious disease: parasitic;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Nervous system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Endocrine system;Nervous system;Nervous system;Nervous system;Endocrine system;Endocrine system;Endocrine system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Endocrine system;Substance dependence;Nervous system;Aging;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Excretory system;Infectious disease: bacterial;Substance dependence;Excretory system	"ko05200//Pathways in cancer;ko04740//Olfactory transduction;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04530//Tight junction;ko05146//Amoebiasis;ko04310//Wnt signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04340//Hedgehog signaling pathway;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0031588//nucleotide-activated protein kinase complex;GO:0031594//neuromuscular junction;GO:0034704//calcium channel complex;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0044853//plasma membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030145//manganese ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0106310//protein serine kinase activity	GO:0001707//mesoderm formation;GO:0001843//neural tube closure;GO:0002027//regulation of heart rate;GO:0003091//renal water homeostasis;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0010737//protein kinase A signaling;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0034380//high-density lipoprotein particle assembly;GO:0034605//cellular response to heat;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043393//regulation of protein binding;GO:0045667//regulation of osteoblast differentiation;GO:0046777//protein autophosphorylation;GO:0046827//positive regulation of protein export from nucleus;GO:0048240//sperm capacitation;GO:0050804//modulation of chemical synaptic transmission;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051726//regulation of cell cycle;GO:0055117//regulation of cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0061136//regulation of proteasomal protein catabolic process;GO:0070417//cellular response to cold;GO:0070613//regulation of protein processing;GO:0071333//cellular response to glucose stimulus;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0071872//cellular response to epinephrine stimulus;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1903779//regulation of cardiac conduction;GO:1990044//protein localization to lipid droplet;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000072071	12.837	14.355	15.535	13.616	15.105	13.763	1762	1769	1398	1343	1609	1374	ADGRL1	adhesion G protein-coupled receptor L1 [Source:HGNC Symbol;Acc:HGNC:20973]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0016524//latrotoxin receptor activity;GO:0030246//carbohydrate binding;GO:0050839//cell adhesion molecule binding	GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0090129//positive regulation of synapse maturation	--
ENSG00000072080	0	0	0	0	0	0	0	0	0	0	0	0	SPP2	secreted phosphoprotein 2 [Source:HGNC Symbol;Acc:HGNC:11256]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0004866//endopeptidase inhibitor activity	GO:0001501//skeletal system development;GO:0010951//negative regulation of endopeptidase activity;GO:0046849//bone remodeling	--
ENSG00000072110	93.098	100.376	80.392	70.752	79.707	68.771	6542	6639	4112	3716	4642	3613	ACTN1	actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Cell motility;Immune disease;Cancer: overview;Cellular community - eukaryotes;Cellular community - eukaryotes;Infectious disease: parasitic;Immune system;Cellular community - eukaryotes	ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04530//Tight junction;ko05146//Amoebiasis;ko04670//Leukocyte transendothelial migration;ko04520//Adherens junction	K05699;K05699;K05699;K05699;K05699;K05699;K05699;K05699;K05699	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0005916//fascia adherens;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031093//platelet alpha granule lumen;GO:0031143//pseudopodium;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0003725//double-stranded RNA binding;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017166//vinculin binding;GO:0030374//nuclear receptor coactivator activity;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0099186//structural constituent of postsynapse	"GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0030220//platelet formation;GO:0036344//platelet morphogenesis;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048041//focal adhesion assembly;GO:0051017//actin filament bundle assembly;GO:0051271//negative regulation of cellular component movement;GO:0051639//actin filament network formation;GO:0055001//muscle cell development;GO:0099173//postsynapse organization"	--
ENSG00000072121	8.517	8.008	9.119	7.195	6.961	7.923	1550	1556	1231	1033	1158	1125	ZFYVE26	zinc finger FYVE-type containing 26 [Source:HGNC Symbol;Acc:HGNC:20761]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0046872//metal ion binding	GO:0000281//mitotic cytokinesis;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007040//lysosome organization;GO:0007049//cell cycle;GO:0032465//regulation of cytokinesis;GO:0051301//cell division;GO:1905037//autophagosome organization	--
ENSG00000072133	1.883	1.543	1.511	1.394	1.237	1.283	321	266	193	175	178	161	RPS6KA6	ribosomal protein S6 kinase A6 [Source:HGNC Symbol;Acc:HGNC:10435]	Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Environmental adaptation;Infectious disease: bacterial;Cancer: overview;Signal transduction;Cell growth and death;Nervous system;Endocrine system;Endocrine and metabolic disease;Nervous system	ko04010//MAPK signaling pathway;ko04714//Thermogenesis;ko05135//Yersinia infection;ko05207//Chemical carcinogenesis - receptor activation;ko04150//mTOR signaling pathway;ko04114//Oocyte meiosis;ko04722//Neurotrophin signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko04720//Long-term potentiation	K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0045992//negative regulation of embryonic development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000381//negative regulation of mesoderm development"	--
ENSG00000072134	8.859	8.138	9.352	11.435	9.017	10.014	608.68	612.28	439.94	417.15	554.33	495.43	EPN2	epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12471	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030125//clathrin vesicle coat;GO:0030128//clathrin coat of endocytic vesicle;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0030276//clathrin binding;GO:0045296//cadherin binding	GO:0006897//endocytosis;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0045747//positive regulation of Notch signaling pathway;GO:1903671//negative regulation of sprouting angiogenesis	--
ENSG00000072135	4.297	4	3.841	3.545	5.525	3.604	258	290	196	192	305	173	PTPN18	protein tyrosine phosphatase non-receptor type 18 [Source:HGNC Symbol;Acc:HGNC:9649]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0001825//blastocyst formation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:1901185//negative regulation of ERBB signaling pathway	--
ENSG00000072163	9.469	8.96	8.401	12.973	9.626	10.134	373	349	256	355	324	300	LIMS2	LIM zinc finger domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16084]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0043066//negative regulation of apoptotic process;GO:0045216//cell-cell junction organization;GO:0050680//negative regulation of epithelial cell proliferation;GO:0098609//cell-cell adhesion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:2000178//negative regulation of neural precursor cell proliferation;GO:2000346//negative regulation of hepatocyte proliferation;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000072182	0	0	0	0.051	0	0	0	0	0	2	0	0	ASIC4	acid sensing ion channel subunit family member 4 [Source:HGNC Symbol;Acc:HGNC:21263]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04831	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0015280//ligand-gated sodium channel activity	GO:0001662//behavioral fear response;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0035725//sodium ion transmembrane transport	--
ENSG00000072195	10.235	9.392	10.656	14.839	13.23	15.676	576	543	396	530	653	571.87	SPEG	striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0042692//muscle cell differentiation	--
ENSG00000072201	4.662	3.287	4.373	4.644	3.925	3.23	282.99	217.67	219.95	210.79	217.97	189.5	LNX1	ligand of numb-protein X 1 [Source:HGNC Symbol;Acc:HGNC:6657]	-	-	-	-	GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000072210	49.476	47.232	52.285	51.982	46.109	49.576	2240	2236	1756	1537	1677	1517	ALDH3A2	aldehyde dehydrogenase 3 family member A2 [Source:HGNC Symbol;Acc:HGNC:403]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism;ko00770//Pantothenate and CoA biosynthesis"	K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042803//protein homodimerization activity;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity;GO:0046577//long-chain-alcohol oxidase activity;GO:0050061//long-chain-aldehyde dehydrogenase activity;GO:0052814//medium-chain-aldehyde dehydrogenase activity"	GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006714//sesquiterpenoid metabolic process;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0008544//epidermis development;GO:0033306//phytol metabolic process;GO:0046458//hexadecanal metabolic process	--
ENSG00000072274	26.78	29.585	27.701	38.63	40.889	43.895	2783	2940	2125	2975	3564	3321	TFRC	transferrin receptor [Source:HGNC Symbol;Acc:HGNC:11763]	Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Cellular Processes	Transport and catabolism;Transport and catabolism;Immune system;Signal transduction;Cell growth and death	ko04144//Endocytosis;ko04145//Phagosome;ko04640//Hematopoietic cell lineage;ko04066//HIF-1 signaling pathway;ko04216//Ferroptosis	K06503;K06503;K06503;K06503;K06503	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0110165//cellular anatomical entity;GO:1903561//extracellular vesicle;GO:1990712//HFE-transferrin receptor complex	GO:0001618//virus receptor activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0004998//transferrin receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0051087//chaperone binding	GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006953//acute-phase response;GO:0007165//signal transduction;GO:0007568//aging;GO:0007584//response to nutrient;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010039//response to iron ion;GO:0010042//response to manganese ion;GO:0010628//positive regulation of gene expression;GO:0010637//negative regulation of mitochondrial fusion;GO:0030316//osteoclast differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031623//receptor internalization;GO:0032526//response to retinoic acid;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033572//transferrin transport;GO:0035556//intracellular signal transduction;GO:0042102//positive regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045780//positive regulation of bone resorption;GO:0045830//positive regulation of isotype switching;GO:0046688//response to copper ion;GO:0046718//viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071466//cellular response to xenobiotic stimulus;GO:0150104//transport across blood-brain barrier;GO:1900182//positive regulation of protein localization to nucleus;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000072310	35.294	38.227	37.192	38.946	38.876	36.564	3056	3203	2275	2428	2784	2344	SREBF1	sterol regulatory element binding transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11289]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease;Endocrine system;Signal transduction;Endocrine and metabolic disease	ko04932//Non-alcoholic fatty liver disease;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance	K07197;K07197;K07197;K07197;K07197	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0032810//sterol response element binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003062//regulation of heart rate by chemical signal;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0007568//aging;GO:0007623//circadian rhythm;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0008610//lipid biosynthetic process;GO:0009267//cellular response to starvation;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010876//lipid localization;GO:0010883//regulation of lipid storage;GO:0014070//response to organic cyclic compound;GO:0019217//regulation of fatty acid metabolic process;GO:0030324//lung development;GO:0030522//intracellular receptor signaling pathway;GO:0031065//positive regulation of histone deacetylation;GO:0031647//regulation of protein stability;GO:0032094//response to food;GO:0032526//response to retinoic acid;GO:0032570//response to progesterone;GO:0032869//cellular response to insulin stimulus;GO:0032933//SREBP signaling pathway;GO:0033762//response to glucagon;GO:0033993//response to lipid;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043434//response to peptide hormone;GO:0045444//fat cell differentiation;GO:0045471//response to ethanol;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046676//negative regulation of insulin secretion;GO:0050796//regulation of insulin secretion;GO:0051591//response to cAMP;GO:0070542//response to fatty acid;GO:0071398//cellular response to fatty acid;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903146//regulation of autophagy of mitochondrion;GO:1903214//regulation of protein targeting to mitochondrion"	bHLH
ENSG00000072315	0	0.012	0.005	0.011	0	0.005	0	3	1	2	0	1	TRPC5	transient receptor potential cation channel subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:12337]	Organismal Systems;Organismal Systems	Development and regeneration;Endocrine system	ko04360//Axon guidance;ko04929//GnRH secretion	K04968;K04968	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030426//growth cone;GO:0034703//cation channel complex;GO:0034704//calcium channel complex;GO:0043025//neuronal cell body;GO:0045121//membrane raft	"GO:0003779//actin binding;GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0030276//clathrin binding;GO:0042805//actinin binding;GO:0051117//ATPase binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0030182//neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045773//positive regulation of axon extension;GO:0050774//negative regulation of dendrite morphogenesis;GO:0051402//neuron apoptotic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902630//regulation of membrane hyperpolarization	--
ENSG00000072364	18.907	17.545	16.177	10.135	11.783	11.743	3537	3288	2165	1426	1945	1690	AFF4	AF4/FMR2 family member 4 [Source:HGNC Symbol;Acc:HGNC:17869]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0032783//super elongation complex;GO:0035327//transcriptionally active chromatin	GO:0005515//protein binding	GO:0007286//spermatid development;GO:0010468//regulation of gene expression	AF-4
ENSG00000072401	9.227	8.595	8.735	7.594	6.31	8.766	502	470	351	306	290	347	UBE2D1	ubiquitin conjugating enzyme E2 D1 [Source:HGNC Symbol;Acc:HGNC:12474]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation;Folding, sorting and degradation"	ko05131//Shigellosis;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K06689;K06689;K06689	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061630//ubiquitin protein ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030514//negative regulation of BMP signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0070936//protein K48-linked ubiquitination;GO:1902916//positive regulation of protein polyubiquitination	--
ENSG00000072415	15.277	12.396	14.735	10.105	10.497	13.59	1625	1337	1024	766	954	1036	PALS1	"protein associated with LIN7 1, MAGUK family member [Source:HGNC Symbol;Acc:HGNC:18669]"	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K06091;K06091;K06091	GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0032991//protein-containing complex;GO:0035749//myelin sheath adaxonal region;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043219//lateral loop;GO:0043220//Schmidt-Lanterman incisure;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding	GO:0002011//morphogenesis of an epithelial sheet;GO:0007009//plasma membrane organization;GO:0010467//gene expression;GO:0016332//establishment or maintenance of polarity of embryonic epithelium;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0032287//peripheral nervous system myelin maintenance;GO:0032288//myelin assembly;GO:0034613//cellular protein localization;GO:0035750//protein localization to myelin sheath abaxonal region;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0048699//generation of neurons;GO:0072659//protein localization to plasma membrane	--
ENSG00000072422	6.623	6.133	5.947	5.976	6.818	5.633	606	564	399	405	527	375	RHOBTB1	Rho related BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18738]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K07868	GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043652//engulfment of apoptotic cell	--
ENSG00000072501	20.736	20.269	21.681	11.477	16.631	15.488	2488	2243	1545	1075	1416	1271	SMC1A	structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04114//Oocyte meiosis;ko04110//Cell cycle	K06636;K06636	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0008278//cohesin complex;GO:0016363//nuclear matrix;GO:0030893//meiotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex;GO:0097431//mitotic spindle pole"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0036033//mediator complex binding;GO:0046982//protein heterodimerization activity	GO:0000070//mitotic sister chromatid segregation;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0009314//response to radiation;GO:0019827//stem cell population maintenance;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0072423//response to DNA damage checkpoint signaling;GO:0090307//mitotic spindle assembly	--
ENSG00000072506	35.264	36.014	40.955	44.591	41.165	38.279	698	718	598	653	687	552	HSD17B10	hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800]	Metabolism;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Amino acid metabolism	"ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko00280//Valine, leucine and isoleucine degradation"	K08683;K08683;K08683;K08683	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0030678//mitochondrial ribonuclease P complex;GO:0042645//mitochondrial nucleoid;GO:0043527//tRNA methyltransferase complex	"GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0008709//cholate 7-alpha-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047015//3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0106281//chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity;GO:0106282//isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity;GO:0106283//ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity"	GO:0006550//isoleucine catabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006699//bile acid biosynthetic process;GO:0007005//mitochondrion organization;GO:0008033//tRNA processing;GO:0008202//steroid metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0051289//protein homotetramerization;GO:0062173//brexanolone metabolic process;GO:0070901//mitochondrial tRNA methylation;GO:0097745//mitochondrial tRNA 5'-end processing;GO:1990180//mitochondrial tRNA 3'-end processing	--
ENSG00000072518	16.84	14.624	17.635	17.354	18.804	19.513	1061	958	818	812	958	917	MARK2	microtubule affinity regulating kinase 2 [Source:HGNC Symbol;Acc:HGNC:3332]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0097427//microtubule bundle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030295//protein kinase activator activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0000422//autophagy of mitochondrion;GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030010//establishment of cell polarity;GO:0030154//cell differentiation;GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0046777//protein autophosphorylation;GO:0050770//regulation of axonogenesis;GO:0051493//regulation of cytoskeleton organization;GO:0051646//mitochondrion localization;GO:0061564//axon development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071963//establishment or maintenance of cell polarity regulating cell shape;GO:1904526//regulation of microtubule binding	--
ENSG00000072571	0.435	0.526	0.24	0.198	0.21	0.416	20	32	11	9	11	15	HMMR	hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06267	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0005540//hyaluronic acid binding	-	--
ENSG00000072609	9.523	11.526	10.375	9.924	10.659	11.145	386	382	298	291	359	307	CHFR	checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455]	-	-	-	-	GO:0005634//nucleus;GO:0016605//PML body	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0000278//mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031648//protein destabilization;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0044779//meiotic spindle checkpoint signaling;GO:0044818//mitotic G2/M transition checkpoint;GO:0051301//cell division	--
ENSG00000072657	0.397	0.382	0.414	0.212	0.161	0.225	91	88	45	36	18	26	TRHDE	thyrotropin releasing hormone degrading enzyme [Source:HGNC Symbol;Acc:HGNC:30748]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008217//regulation of blood pressure;GO:0043171//peptide catabolic process	--
ENSG00000072682	20.793	22.542	17.563	20.093	22.607	23.854	1037.07	1085.44	644.1	723.29	867.91	845.46	P4HA2	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00472;K00472	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0019511//peptidyl-proline hydroxylation;GO:0022900//electron transport chain	--
ENSG00000072694	0	0	0	0	0.159	0	0	0	0	0	4	0	FCGR2B	Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618]	Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: viral;Development and regeneration	ko05152//Tuberculosis;ko04145//Phagosome;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko04380//Osteoclast differentiation	K12560;K12560;K12560;K12560;K12560;K12560;K12560	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0044297//cell body	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019772//low-affinity IgG receptor activity;GO:0019864//IgG binding;GO:0044877//protein-containing complex binding	"GO:0001811//negative regulation of type I hypersensitivity;GO:0001814//negative regulation of antibody-dependent cellular cytotoxicity;GO:0001818//negative regulation of cytokine production;GO:0002266//follicular dendritic cell activation;GO:0002313//mature B cell differentiation involved in immune response;GO:0002316//follicular B cell differentiation;GO:0002436//immune complex clearance by monocytes and macrophages;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0002622//regulation of B cell antigen processing and presentation;GO:0002638//negative regulation of immunoglobulin production;GO:0002819//regulation of adaptive immune response;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0002922//positive regulation of humoral immune response;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006898//receptor-mediated endocytosis;GO:0006911//phagocytosis, engulfment;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0009617//response to bacterium;GO:0010469//regulation of signaling receptor activity;GO:0016064//immunoglobulin mediated immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0021549//cerebellum development;GO:0030889//negative regulation of B cell proliferation;GO:0032693//negative regulation of interleukin-10 production;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043031//negative regulation of macrophage activation;GO:0043318//negative regulation of cytotoxic T cell degranulation;GO:0045088//regulation of innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050765//negative regulation of phagocytosis;GO:0050766//positive regulation of phagocytosis;GO:0050776//regulation of immune response;GO:0050777//negative regulation of immune response;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0050869//negative regulation of B cell activation;GO:0071219//cellular response to molecule of bacterial origin;GO:0090264//regulation of immune complex clearance by monocytes and macrophages;GO:1901216//positive regulation of neuron death;GO:1902564//negative regulation of neutrophil activation;GO:1902950//regulation of dendritic spine maintenance;GO:1904646//cellular response to amyloid-beta;GO:1905898//positive regulation of response to endoplasmic reticulum stress;GO:2001199//negative regulation of dendritic cell differentiation"	--
ENSG00000072736	7.168	6.555	7.503	5.816	5.684	8.445	829	758	593	474	524	620	NFATC3	nuclear factor of activated T cells 3 [Source:HGNC Symbol;Acc:HGNC:7777]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Development and regeneration;Signal transduction;Signal transduction;Infectious disease: viral;Cell growth and death;Endocrine system;Immune system;Immune system;Immune system;Immune system;Immune system;Cancer: overview	ko04010//MAPK signaling pathway;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333;K17333	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0010468//regulation of gene expression;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1905064//negative regulation of vascular associated smooth muscle cell differentiation"	RHD
ENSG00000072756	5.542	4.475	4.572	4.182	3.853	4.842	228.04	192.17	144	131.19	132	136	TRNT1	tRNA nucleotidyl transferase 1 [Source:HGNC Symbol;Acc:HGNC:17341]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004810//tRNA adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016437//tRNA cytidylyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0034062//5'-3' RNA polymerase activity;GO:0052927//CTP:tRNA cytidylyltransferase activity;GO:0052928//CTP:3'-cytidine-tRNA cytidylyltransferase activity;GO:0052929//ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	GO:0001680//tRNA 3'-terminal CCA addition;GO:0006396//RNA processing;GO:0008033//tRNA processing;GO:0042780//tRNA 3'-end processing;GO:1990180//mitochondrial tRNA 3'-end processing	--
ENSG00000072778	106.623	105.659	128.841	120.041	127.276	139.446	4043	4160	3682	3431	4003	3812	ACADVL	acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K09479;K09479;K09479;K09479	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane;GO:0042645//mitochondrial nucleoid	"GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding"	GO:0001659//temperature homeostasis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0009409//response to cold;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030855//epithelial cell differentiation;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0046322//negative regulation of fatty acid oxidation;GO:0090181//regulation of cholesterol metabolic process	--
ENSG00000072786	2.627	2.133	2.061	1.767	2.208	2.08	321	262	186	160	228	185	STK10	serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388]	Organismal Systems	Endocrine system	ko04914//Progesterone-mediated oocyte maturation	K08837	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0046777//protein autophosphorylation;GO:0071593//lymphocyte aggregation;GO:2000401//regulation of lymphocyte migration	--
ENSG00000072803	32.389	29.114	30.063	27.805	30.743	33.756	2047	1882	1354	1334	1639	1578	FBXW11	F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems	"Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cell growth and death;Signal transduction;Folding, sorting and degradation;Cell growth and death;Signal transduction;Environmental adaptation"	ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm	K03362;K03362;K03362;K03362;K03362;K03362;K03362;K03362;K03362	GO:0000151//ubiquitin ligase complex;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005881//cytoplasmic microtubule;GO:0019005//SCF ubiquitin ligase complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:1904115//axon cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0051010//microtubule plus-end binding;GO:0061630//ubiquitin protein ligase activity;GO:0070840//dynein complex binding	"GO:0000132//establishment of mitotic spindle orientation;GO:0000209//protein polyubiquitination;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0007097//nuclear migration;GO:0007281//germ cell development;GO:0008090//retrograde axonal transport;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0031023//microtubule organizing center organization;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031648//protein destabilization;GO:0042753//positive regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045862//positive regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0047496//vesicle transport along microtubule;GO:0048511//rhythmic process;GO:0048854//brain morphogenesis;GO:1901223//negative regulation of NIK/NF-kappaB signaling"	--
ENSG00000072818	0.019	0.076	0.078	0.026	0.045	0.053	1	4	3	1	2	2	ACAP1	"ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [Source:HGNC Symbol;Acc:HGNC:16467]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12489	GO:0005768//endosome;GO:0016020//membrane;GO:0055038//recycling endosome membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0050790//regulation of catalytic activity	--
ENSG00000072832	6.267	6.588	5.404	6.696	8.185	5.831	379	400	241	299	418	256	CRMP1	collapsin response mediator protein 1 [Source:HGNC Symbol;Acc:HGNC:2365]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030426//growth cone;GO:0030496//midbody;GO:0042995//cell projection;GO:0043204//perikaryon	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0031005//filamin binding;GO:0042802//identical protein binding"	GO:0000226//microtubule cytoskeleton organization;GO:0006139//nucleobase-containing compound metabolic process;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0010977//negative regulation of neuron projection development;GO:1904530//negative regulation of actin filament binding	--
ENSG00000072840	7.884	7.349	8.635	7.585	8.116	6.619	1051	973	781	749	894	642	EVC	EvC ciliary complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:3497]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K19605	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0098797//plasma membrane protein complex	-	GO:0001501//skeletal system development;GO:0003416//endochondral bone growth;GO:0007224//smoothened signaling pathway;GO:0007517//muscle organ development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051216//cartilage development	--
ENSG00000072849	18.879	15.983	16.247	12.643	14.019	16.766	811	739	598	581	577	613	DERL2	derlin 2 [Source:HGNC Symbol;Acc:HGNC:17943]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13989	GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0051787//misfolded protein binding;GO:1990381//ubiquitin-specific protease binding	"GO:0001967//suckling behavior;GO:0006950//response to stress;GO:0006986//response to unfolded protein;GO:0008284//positive regulation of cell population proliferation;GO:0010498//proteasomal protein catabolic process;GO:0030307//positive regulation of cell growth;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0033554//cellular response to stress;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000072858	0.01	0	0	0.027	0	0	1	0	0	2	0	0	SIDT1	SID1 transmembrane family member 1 [Source:HGNC Symbol;Acc:HGNC:25967]	-	-	-	-	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0015485//cholesterol binding;GO:0051033//RNA transmembrane transporter activity	GO:0050658//RNA transport	--
ENSG00000072864	7.442	6.933	9.245	8.282	7.758	8.495	329	288	282	252.76	271.24	261	NDE1	nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0031616//spindle pole centrosome;GO:0032154//cleavage furrow;GO:0045202//synapse"	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001764//neuron migration;GO:0007020//microtubule nucleation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007100//mitotic centrosome separation;GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0016477//cell migration;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0031023//microtubule organizing center organization;GO:0047496//vesicle transport along microtubule;GO:0051298//centrosome duplication;GO:0051301//cell division;GO:0051303//establishment of chromosome localization;GO:0051642//centrosome localization	--
ENSG00000072952	1.038	1.257	0.851	0.688	0.702	0.819	126	130	59	62	72	50	IRAG1	"inositol 1,4,5-triphosphate receptor associated 1 [Source:HGNC Symbol;Acc:HGNC:7237]"	Environmental Information Processing;Organismal Systems	Signal transduction;Circulatory system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction	K12337;K12337	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031095//platelet dense tubular network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0019934//cGMP-mediated signaling	--
ENSG00000072954	42.219	43.243	53.343	66.373	62.379	68.93	2304	2372	2150	2683	2876	2737	TMEM38A	transmembrane protein 38A [Source:HGNC Symbol;Acc:HGNC:28462]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0005267//potassium channel activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007029//endoplasmic reticulum organization;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0071313//cellular response to caffeine;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000072958	40.856	42.607	43.964	49.632	47.37	45.61	1679	1752	1319	1481	1608	1342	AP1M1	adaptor related protein complex 1 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:13667]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12393;K12393	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030121//AP-1 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032438//melanosome organization;GO:0035646//endosome to melanosome transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000073008	8.643	10.624	8.842	9.448	9.93	11.221	617	656	459	513	573	499	PVR	PVR cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:9705]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06539	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0050839//cell adhesion molecule binding	GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046718//viral entry into host cell;GO:0060370//susceptibility to T cell mediated cytotoxicity	--
ENSG00000073050	18.377	17.065	17.282	15.31	14.816	16.588	675	639	503	459	499	435	XRCC1	X-ray repair cross complementing 1 [Source:HGNC Symbol;Acc:HGNC:12828]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10803	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0070522//ERCC4-ERCC1 complex"	GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0032356//oxidized DNA binding;GO:1990599//3' overhang single-stranded DNA endodeoxyribonuclease activity	GO:0000012//single strand break repair;GO:0001666//response to hypoxia;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010836//negative regulation of protein ADP-ribosylation;GO:0021587//cerebellum morphogenesis;GO:0021766//hippocampus development;GO:0033194//response to hydroperoxide;GO:0050882//voluntary musculoskeletal movement;GO:0061819//telomeric DNA-containing double minutes formation;GO:1903518//positive regulation of single strand break repair;GO:1904877//positive regulation of DNA ligase activity;GO:1905765//negative regulation of protection from non-homologous end joining at telomere;GO:1990414//replication-born double-strand break repair via sister chromatid exchange	--
ENSG00000073060	217.27	255.652	192.769	187.127	198.51	156.786	8073	9239	5549	5003	6151	4283	SCARB1	scavenger receptor class B member 1 [Source:HGNC Symbol;Acc:HGNC:1664]	Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Transport and catabolism;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Digestive system;Endocrine system;Endocrine system;Digestive system;Digestive system;Digestive system	ko04145//Phagosome;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04976//Bile secretion;ko04927//Cortisol synthesis and secretion;ko04913//Ovarian steroidogenesis;ko04979//Cholesterol metabolism;ko04975//Fat digestion and absorption;ko04977//Vitamin digestion and absorption	K13885;K13885;K13885;K13885;K13885;K13885;K13885;K13885;K13885;K13885	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0001540//amyloid-beta binding;GO:0001618//virus receptor activity;GO:0001786//phosphatidylserine binding;GO:0001875//lipopolysaccharide immune receptor activity;GO:0005044//scavenger receptor activity;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0030169//low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0034186//apolipoprotein A-I binding;GO:0070506//high-density lipoprotein particle receptor activity	GO:0001935//endothelial cell proliferation;GO:0006707//cholesterol catabolic process;GO:0006869//lipid transport;GO:0010595//positive regulation of endothelial cell migration;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010886//positive regulation of cholesterol storage;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0015914//phospholipid transport;GO:0015920//lipopolysaccharide transport;GO:0030301//cholesterol transport;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032497//detection of lipopolysaccharide;GO:0033344//cholesterol efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0034381//plasma lipoprotein particle clearance;GO:0034383//low-density lipoprotein particle clearance;GO:0034384//high-density lipoprotein particle clearance;GO:0035461//vitamin transmembrane transport;GO:0042060//wound healing;GO:0042632//cholesterol homeostasis;GO:0043534//blood vessel endothelial cell migration;GO:0043654//recognition of apoptotic cell;GO:0043691//reverse cholesterol transport;GO:0044406//adhesion of symbiont to host;GO:0046718//viral entry into host cell;GO:0050764//regulation of phagocytosis;GO:0050892//intestinal absorption;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0070328//triglyceride homeostasis;GO:0070508//cholesterol import	--
ENSG00000073067	4.276	5.06	5.876	14.15	10.183	9.414	206	245	209	505	400	330	CYP2W1	cytochrome P450 family 2 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:20243]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K07423;K07423	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0001972//retinoic acid binding;GO:0004497//monooxygenase activity;GO:0005503//all-trans retinal binding;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:1904768//all-trans-retinol binding"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0034653//retinoic acid catabolic process;GO:0046222//aflatoxin metabolic process	--
ENSG00000073111	9.378	11.258	10.55	8.908	8.475	7.757	668	806	555	470	510	402	MCM2	minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02540;K02540	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0042555//MCM complex;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0043138//3'-5' DNA helicase activity;GO:0046872//metal ion binding	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006334//nucleosome assembly;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:0071353//cellular response to interleukin-4;GO:0090102//cochlea development;GO:1902975//mitotic DNA replication initiation;GO:1905775//negative regulation of DNA helicase activity	--
ENSG00000073146	0.588	0.636	0.33	0.516	0.624	0.53	34	37	18	15	27	21	MOV10L1	Mov10 like RISC complex RNA helicase 1 [Source:HGNC Symbol;Acc:HGNC:7201]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043186//P granule;GO:0071546//pi-body	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007141//male meiosis I;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process;GO:0035194//post-transcriptional gene silencing by RNA;GO:0043046//DNA methylation involved in gamete generation	--
ENSG00000073150	1.688	1.996	1.754	1.855	2.206	2.28	106	125	80	87	118	105	PANX2	pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0015267//channel activity;GO:0022829//wide pore channel activity	GO:0002931//response to ischemia;GO:0006811//ion transport;GO:0006812//cation transport;GO:0007267//cell-cell signaling;GO:0032732//positive regulation of interleukin-1 production;GO:0055085//transmembrane transport	--
ENSG00000073169	9.461	9.433	9.693	10.263	10.023	11.029	448	449	339	360	401	380	-	-	-	-	-	-	-	-	-	-
ENSG00000073282	0.044	0.309	0.102	0.069	0.207	0.1	4	16	6	4	17	4	TP63	tumor protein p63 [Source:HGNC Symbol;Acc:HGNC:15979]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K10149	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0043005//neuron projection	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0050699//WW domain binding;GO:0097371//MDM2/MDM4 family protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001736//establishment of planar polarity;GO:0001738//morphogenesis of a polarized epithelium;GO:0001942//hair follicle development;GO:0002064//epithelial cell development;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007219//Notch signaling pathway;GO:0007283//spermatogenesis;GO:0007389//pattern specification process;GO:0007499//ectoderm and mesoderm interaction;GO:0007568//aging;GO:0007569//cell aging;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008544//epidermis development;GO:0009887//animal organ morphogenesis;GO:0009913//epidermal cell differentiation;GO:0009954//proximal/distal pattern formation;GO:0010259//multicellular organism aging;GO:0010481//epidermal cell division;GO:0010482//regulation of epidermal cell division;GO:0010838//positive regulation of keratinocyte proliferation;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030850//prostate gland development;GO:0030855//epithelial cell differentiation;GO:0030859//polarized epithelial cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0032502//developmental process;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0036342//post-anal tail morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043589//skin morphogenesis;GO:0045617//negative regulation of keratinocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048485//sympathetic nervous system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048807//female genitalia morphogenesis;GO:0051262//protein tetramerization;GO:0051402//neuron apoptotic process;GO:0060197//cloacal septation;GO:0060513//prostatic bud formation;GO:0060529//squamous basal epithelial stem cell differentiation involved in prostate gland acinus development;GO:0061436//establishment of skin barrier;GO:0098773//skin epidermis development;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1904674//positive regulation of somatic stem cell population maintenance;GO:1904888//cranial skeletal system development;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2000381//negative regulation of mesoderm development;GO:2000773//negative regulation of cellular senescence;GO:2001235//positive regulation of apoptotic signaling pathway"	P53
ENSG00000073331	4.486	3.969	4.068	2.83	3.228	3.709	458	384	266	215	266	267	ALPK1	alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0048029//monosaccharide binding;GO:0106310//protein serine kinase activity	GO:0002376//immune system process;GO:0002753//cytoplasmic pattern recognition receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0060271//cilium assembly	--
ENSG00000073350	9.228	9.609	8.749	10.515	11.016	10.587	485	520	331	424	524	347	LLGL2	LLGL scribble cell polarity complex component 2 [Source:HGNC Symbol;Acc:HGNC:6629]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K06094;K06094;K06094	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0030864//cortical actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0045159//myosin II binding	GO:0006887//exocytosis;GO:0007049//cell cycle;GO:0008593//regulation of Notch signaling pathway;GO:0015820//leucine transport;GO:0030866//cortical actin cytoskeleton organization;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0050708//regulation of protein secretion;GO:0050790//regulation of catalytic activity;GO:0051294//establishment of spindle orientation;GO:0051301//cell division	--
ENSG00000073417	2.359	2.028	2.331	2.28	2.475	3.284	191	169	140	117	157	163	PDE8A	phosphodiesterase 8A [Source:HGNC Symbol;Acc:HGNC:8793]	Metabolism;Human Diseases;Metabolism;Human Diseases;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Nucleotide metabolism;Substance dependence;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04927//Cortisol synthesis and secretion	K18437;K18437;K18437;K18437;K18437	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	"GO:0001934//positive regulation of protein phosphorylation;GO:0006198//cAMP catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0060548//negative regulation of cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1903206//negative regulation of hydrogen peroxide-induced cell death"	--
ENSG00000073464	14.722	14.268	13.206	11.393	12.803	12.646	1866	1941	1283	1049	1338	1290	CLCN4	chloride voltage-gated channel 4 [Source:HGNC Symbol;Acc:HGNC:2022]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K05012	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1905515//non-motile cilium assembly	--
ENSG00000073536	4.344	6.208	5.335	5.211	5.637	4.017	256	324	248	243	258.72	193	NLE1	notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0000027//ribosomal large subunit assembly;GO:0001756//somitogenesis;GO:0001822//kidney development;GO:0001826//inner cell mass cell differentiation;GO:0007219//Notch signaling pathway;GO:0042273//ribosomal large subunit biogenesis;GO:0045930//negative regulation of mitotic cell cycle;GO:0048705//skeletal system morphogenesis;GO:0061484//hematopoietic stem cell homeostasis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000073578	47.442	45.567	45.79	46.012	44.258	43.231	2561.38	2468.67	1811.91	1799.49	1977.69	1686.09	SDHA	succinate dehydrogenase complex flavoprotein subunit A [Source:HGNC Symbol;Acc:HGNC:10680]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234	"GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0016020//membrane"	"GO:0000104//succinate dehydrogenase activity;GO:0005515//protein binding;GO:0008177//succinate dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding"	"GO:0006099//tricarboxylic acid cycle;GO:0006105//succinate metabolic process;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0007399//nervous system development;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000073584	51.367	50.756	44.338	34.562	38.545	38.6	2342.72	2265.44	1462.82	1141.69	1484	1290.67	SMARCE1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [Source:HGNC Symbol;Acc:HGNC:11109]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11651;K11651	GO:0000228//nuclear chromosome;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016922//nuclear receptor binding;GO:0031492//nucleosomal DNA binding;GO:0047485//protein N-terminus binding	"GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	HMG
ENSG00000073598	0	0	0	0	0.096	0	0	0	0	0	2.28	0	FNDC8	fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000073605	0.576	0.227	0.322	0.48	0.733	0.564	16	7	6	12	19	10	GSDMB	gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001786//phosphatidylserine binding;GO:0003674//molecular_function;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding"	GO:0012501//programmed cell death;GO:0019835//cytolysis;GO:0042742//defense response to bacterium;GO:0070269//pyroptosis	--
ENSG00000073614	6.828	6.543	6.064	4.584	4.549	4.543	1410	1456	994	751	853	731	KDM5A	lysine demethylase 5A [Source:HGNC Symbol;Acc:HGNC:9886]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032993//protein-DNA complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032452//histone demethylase activity;GO:0034647//histone H3-tri/di/monomethyl-lysine-4 demethylase activity;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0032922//circadian regulation of gene expression;GO:0034720//histone H3-K4 demethylation;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0051090//regulation of DNA-binding transcription factor activity;GO:1901726//negative regulation of histone deacetylase activity"	--
ENSG00000073670	0.57	0.453	0.425	0.585	0.476	0.476	46	41	20	33	38	26	ADAM11	ADAM metallopeptidase domain 11 [Source:HGNC Symbol;Acc:HGNC:189]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007229//integrin-mediated signaling pathway	--
ENSG00000073711	7.199	4.371	3.737	3.978	4.311	4.008	913	569	386	381	464	384	PPP2R3A	protein phosphatase 2 regulatory subunit B''alpha [Source:HGNC Symbol;Acc:HGNC:9307]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11583;K11583;K11583;K11583;K11583;K11583;K11583	GO:0000159//protein phosphatase type 2A complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding	GO:0001754//eye photoreceptor cell differentiation;GO:0006470//protein dephosphorylation;GO:0007525//somatic muscle development;GO:0045732//positive regulation of protein catabolic process;GO:0050790//regulation of catalytic activity;GO:0061053//somite development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0090249//regulation of cell migration involved in somitogenic axis elongation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000073712	22.902	20.54	19.191	13.39	15.806	20.55	1462	1290	899	663	878	956	FERMT2	FERM domain containing kindlin 2 [Source:HGNC Symbol;Acc:HGNC:15767]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031258//lamellipodium membrane;GO:0031674//I band;GO:0042995//cell projection	"GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0046332//SMAD binding;GO:0051015//actin filament binding"	"GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016055//Wnt signaling pathway;GO:0022604//regulation of cell morphogenesis;GO:0030335//positive regulation of cell migration;GO:0033622//integrin activation;GO:0033625//positive regulation of integrin activation;GO:0034334//adherens junction maintenance;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035505//positive regulation of myosin light chain kinase activity;GO:0043116//negative regulation of vascular permeability;GO:0043547//positive regulation of GTPase activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0048041//focal adhesion assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0060173//limb development;GO:0060548//negative regulation of cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072657//protein localization to membrane;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900182//positive regulation of protein localization to nucleus;GO:1902414//protein localization to cell junction;GO:1902462//positive regulation of mesenchymal stem cell proliferation;GO:1903691//positive regulation of wound healing, spreading of epidermal cells"	--
ENSG00000073734	0.016	0.007	0.009	0.046	0	0	1	1	1	2	0	0	ABCB11	ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42]	Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing	Drug resistance: antineoplastic;Digestive system;Digestive system;Membrane transport	ko01522//Endocrine resistance;ko04976//Bile secretion;ko04979//Cholesterol metabolism;ko02010//ABC transporters	K05664;K05664;K05664;K05664	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0045177//apical part of cell;GO:0046581//intercellular canaliculus;GO:0046691//intracellular canaliculus;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015126//canalicular bile acid transmembrane transporter activity;GO:0015144//carbohydrate transmembrane transporter activity;GO:0015432//ABC-type bile acid transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006631//fatty acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0006979//response to oxidative stress;GO:0008206//bile acid metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010468//regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0015722//canalicular bile acid transport;GO:0016567//protein ubiquitination;GO:0031998//regulation of fatty acid beta-oxidation;GO:0034219//carbohydrate transmembrane transport;GO:0038183//bile acid signaling pathway;GO:0042632//cholesterol homeostasis;GO:0043627//response to estrogen;GO:0045471//response to ethanol;GO:0046618//xenobiotic export;GO:0055085//transmembrane transport;GO:0055088//lipid homeostasis;GO:0055091//phospholipid homeostasis;GO:0071466//cellular response to xenobiotic stimulus;GO:0120188//regulation of bile acid secretion;GO:0120189//positive regulation of bile acid secretion;GO:1904251//regulation of bile acid metabolic process;GO:1904486//response to 17alpha-ethynylestradiol	--
ENSG00000073737	0.296	0.57	0.045	0.125	0.254	0.045	9	19	1	2	7	1	DHRS9	dehydrogenase/reductase 9 [Source:HGNC Symbol;Acc:HGNC:16888]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11149;K11149	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016854//racemase and epimerase activity;GO:0047023//androsterone dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity"	GO:0002138//retinoic acid biosynthetic process;GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0030855//epithelial cell differentiation;GO:0042448//progesterone metabolic process;GO:0042572//retinol metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process	--
ENSG00000073754	0	0	0	0	0	0	0	0	0	0	0	0	CD5L	CD5 molecule like [Source:HGNC Symbol;Acc:HGNC:1690]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity	GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0030449//regulation of complement activation;GO:0031638//zymogen activation;GO:1903661//positive regulation of complement-dependent cytotoxicity	--
ENSG00000073756	0.075	0	0.014	0	0	0	7	0	1	0	0	0	PTGS2	prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Endocrine system;Nervous system;Infectious disease: parasitic;Nervous system;Signal transduction;Immune system;Immune system;Cancer: specific types;Cancer: overview;Lipid metabolism;Signal transduction;Endocrine system;Endocrine system	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05163//Human cytomegalovirus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05140//Leishmaniasis;ko04726//Serotonergic synapse;ko04668//TNF signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05204//Chemical carcinogenesis - DNA adducts;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis	K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987;K11987	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle	"GO:0004601//peroxidase activity;GO:0004666//prostaglandin-endoperoxide synthase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	"GO:0001516//prostaglandin biosynthetic process;GO:0001525//angiogenesis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0007566//embryo implantation;GO:0007568//aging;GO:0007612//learning;GO:0007613//memory;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009750//response to fructose;GO:0010033//response to organic substance;GO:0010042//response to manganese ion;GO:0010226//response to lithium ion;GO:0010243//response to organonitrogen compound;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010942//positive regulation of cell death;GO:0014070//response to organic cyclic compound;GO:0019233//sensory perception of pain;GO:0019371//cyclooxygenase pathway;GO:0030282//bone mineralization;GO:0030728//ovulation;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0031622//positive regulation of fever generation;GO:0031915//positive regulation of synaptic plasticity;GO:0032227//negative regulation of synaptic transmission, dopaminergic;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033280//response to vitamin D;GO:0034097//response to cytokine;GO:0034605//cellular response to heat;GO:0034612//response to tumor necrosis factor;GO:0034644//cellular response to UV;GO:0035633//maintenance of blood-brain barrier;GO:0042127//regulation of cell population proliferation;GO:0042307//positive regulation of protein import into nucleus;GO:0042633//hair cycle;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045786//negative regulation of cell cycle;GO:0045907//positive regulation of vasoconstriction;GO:0045986//negative regulation of smooth muscle contraction;GO:0045987//positive regulation of smooth muscle contraction;GO:0046697//decidualization;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050873//brown fat cell differentiation;GO:0051384//response to glucocorticoid;GO:0051926//negative regulation of calcium ion transport;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070542//response to fatty acid;GO:0071260//cellular response to mechanical stimulus;GO:0071284//cellular response to lead ion;GO:0071318//cellular response to ATP;GO:0071456//cellular response to hypoxia;GO:0071471//cellular response to non-ionic osmotic stress;GO:0071498//cellular response to fluid shear stress;GO:0071636//positive regulation of transforming growth factor beta production;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090271//positive regulation of fibroblast growth factor production;GO:0090336//positive regulation of brown fat cell differentiation;GO:0090362//positive regulation of platelet-derived growth factor production;GO:0098869//cellular oxidant detoxification;GO:0150077//regulation of neuroinflammatory response;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:1990776//response to angiotensin"	--
ENSG00000073792	10.351	8.538	7.443	6.232	7.352	8.2	655	555	375	310	382	395	IGF2BP2	insulin like growth factor 2 mRNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:28867]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010494//cytoplasmic stress granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0045182//translation regulator activity;GO:0048027//mRNA 5'-UTR binding;GO:1990247//N6-methyladenosine-containing RNA binding	GO:0001817//regulation of cytokine production;GO:0006417//regulation of translation;GO:0007399//nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0017148//negative regulation of translation;GO:0051028//mRNA transport;GO:0051252//regulation of RNA metabolic process;GO:0070934//CRD-mediated mRNA stabilization	--
ENSG00000073803	12.28	11.656	12.671	9.835	12.153	11.219	466	451	348	283	370	298	MAP3K13	mitogen-activated protein kinase kinase kinase 13 [Source:HGNC Symbol;Acc:HGNC:6852]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04422	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding;GO:0106137//IkappaB kinase complex binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0014042//positive regulation of neuron maturation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0043507//positive regulation of JUN kinase activity;GO:0045773//positive regulation of axon extension;GO:0045860//positive regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051403//stress-activated MAPK cascade;GO:0150012//positive regulation of neuron projection arborization;GO:1905492//positive regulation of branching morphogenesis of a nerve	--
ENSG00000073849	16.166	14.249	14.656	15.686	17.635	16.841	1333	1311	1022	1104	1377	1164	ST6GAL1	"ST6 beta-galactoside alpha-2,6-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10860]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00514//Other types of O-glycan biosynthesis	K00778;K00778;K00778	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003835//beta-galactoside alpha-2,6-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042803//protein homodimerization activity"	GO:0006054//N-acetylneuraminate metabolic process;GO:0006486//protein glycosylation;GO:0006959//humoral immune response;GO:0016266//O-glycan processing;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019082//viral protein processing;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0045471//response to ethanol;GO:0050922//negative regulation of chemotaxis;GO:0097503//sialylation;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:1990743//protein sialylation;GO:2000110//negative regulation of macrophage apoptotic process	--
ENSG00000073861	0	0	0	0	0	0	0	0	0	0	0	0	TBX21	T-box transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11599]	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04659//Th17 cell differentiation;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K10166;K10166;K10166	GO:0005634//nucleus;GO:0043025//neuronal cell body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001708//cell fate specification;GO:0002296//T-helper 1 cell lineage commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0030217//T cell differentiation;GO:0032703//negative regulation of interleukin-2 production;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045580//regulation of T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050776//regulation of immune response;GO:0071310//cellular response to organic substance;GO:0072676//lymphocyte migration;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000329//negative regulation of T-helper 17 cell lineage commitment;GO:2000552//negative regulation of T-helper 2 cell cytokine production;GO:2000556//positive regulation of T-helper 1 cell cytokine production"	T-box
ENSG00000073910	1.492	1.409	1.483	1.066	1.631	1.731	349	332	221	189	332	292	FRY	FRY microtubule binding protein [Source:HGNC Symbol;Acc:HGNC:20367]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0030427//site of polarized growth	GO:0004857//enzyme inhibitor activity	GO:0000902//cell morphogenesis;GO:0031175//neuron projection development;GO:0043086//negative regulation of catalytic activity;GO:1904428//negative regulation of tubulin deacetylation	--
ENSG00000073921	57.762	57.137	52.47	44.189	51.853	44.567	2891	2619	1845	1506	1839	1724	PICALM	phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]	-	-	-	-	GO:0005634//nucleus;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0016020//membrane;GO:0030132//clathrin coat of coated pit;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0042734//presynaptic membrane;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045211//postsynaptic membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070381//endosome to plasma membrane transport vesicle;GO:0097418//neurofibrillary tangle;GO:0098894//extrinsic component of presynaptic endocytic zone membrane	"GO:0000149//SNARE binding;GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005545//1-phosphatidylinositol binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0030276//clathrin binding;GO:0031267//small GTPase binding;GO:0032050//clathrin heavy chain binding;GO:0045296//cadherin binding;GO:0048156//tau protein binding;GO:0050750//low-density lipoprotein particle receptor binding"	"GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006900//vesicle budding from membrane;GO:0007409//axonogenesis;GO:0007611//learning or memory;GO:0010629//negative regulation of gene expression;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0016188//synaptic vesicle maturation;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0030097//hemopoiesis;GO:0030100//regulation of endocytosis;GO:0031623//receptor internalization;GO:0032880//regulation of protein localization;GO:0035459//vesicle cargo loading;GO:0043547//positive regulation of GTPase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0048268//clathrin coat assembly;GO:0048813//dendrite morphogenesis;GO:0055072//iron ion homeostasis;GO:0065003//protein-containing complex assembly;GO:0072583//clathrin-dependent endocytosis;GO:0090647//modulation of age-related behavioral decline;GO:0097494//regulation of vesicle size;GO:0097753//membrane bending;GO:0150093//amyloid-beta clearance by transcytosis;GO:1901216//positive regulation of neuron death;GO:1902004//positive regulation of amyloid-beta formation;GO:1902959//regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:1903077//negative regulation of protein localization to plasma membrane;GO:1905224//clathrin-coated pit assembly;GO:2000009//negative regulation of protein localization to cell surface;GO:2000369//regulation of clathrin-dependent endocytosis"	--
ENSG00000073969	11.814	13.973	11.827	11.022	13.136	10.896	976	1112	695	673	860	655	NSF	"N-ethylmaleimide sensitive factor, vesicle fusing ATPase [Source:HGNC Symbol;Acc:HGNC:8016]"	Organismal Systems;Organismal Systems;Organismal Systems	Nervous system;Nervous system;Excretory system	ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle;ko04962//Vasopressin-regulated water reabsorption	K06027;K06027;K06027	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0043198//dendritic shaft;GO:0043229//intracellular organelle	GO:0000149//SNARE binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017075//syntaxin-1 binding;GO:0019901//protein kinase binding;GO:0019905//syntaxin binding;GO:0030165//PDZ domain binding;GO:0035255//ionotropic glutamate receptor binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0140545//protein disaggregase activity	GO:0001921//positive regulation of receptor recycling;GO:0006813//potassium ion transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0017157//regulation of exocytosis;GO:0035494//SNARE complex disassembly;GO:0043001//Golgi to plasma membrane protein transport;GO:0045026//plasma membrane fusion;GO:0045732//positive regulation of protein catabolic process	--
ENSG00000074047	2.915	3.206	3.673	3.243	4.628	3.102	387	403	325	290	310	256	GLI2	GLI family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4318]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04390//Hippo signaling pathway;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K16798;K16798;K16798;K16798	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:1990788//GLI-SUFU complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0002009//morphogenesis of an epithelium;GO:0002062//chondrocyte differentiation;GO:0002076//osteoblast development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007389//pattern specification process;GO:0007411//axon guidance;GO:0007418//ventral midline development;GO:0007442//hindgut morphogenesis;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0021508//floor plate formation;GO:0021513//spinal cord dorsal/ventral patterning;GO:0021517//ventral spinal cord development;GO:0021522//spinal cord motor neuron differentiation;GO:0021696//cerebellar cortex morphogenesis;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0021904//dorsal/ventral neural tube patterning;GO:0021915//neural tube development;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0021965//spinal cord ventral commissure morphogenesis;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030879//mammary gland development;GO:0030902//hindbrain development;GO:0031069//hair follicle morphogenesis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0035295//tube development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0045666//positive regulation of neuron differentiation;GO:0045740//positive regulation of DNA replication;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048566//embryonic digestive tract development;GO:0048589//developmental growth;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048666//neuron development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048856//anatomical structure development;GO:0060032//notochord regression;GO:0060322//head development;GO:0060513//prostatic bud formation;GO:0060603//mammary gland duct morphogenesis;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0071407//cellular response to organic cyclic compound;GO:0090103//cochlea morphogenesis;GO:1901620//regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1990787//negative regulation of hh target transcription factor activity"	zf-C2H2
ENSG00000074054	14.53	13.572	13.425	8.335	10.583	10.76	2384	2242	1626	1013	1466	1285	CLASP1	cytoplasmic linker associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17088]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030981//cortical microtubule cytoskeleton;GO:0031592//centrosomal corona;GO:0035371//microtubule plus-end;GO:0043232//intracellular non-membrane-bounded organelle;GO:0045180//basal cortex;GO:0072686//mitotic spindle"	GO:0002162//dystroglycan binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043515//kinetochore binding;GO:0051010//microtubule plus-end binding	"GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0006903//vesicle targeting;GO:0007020//microtubule nucleation;GO:0007026//negative regulation of microtubule depolymerization;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007163//establishment or maintenance of cell polarity;GO:0010458//exit from mitosis;GO:0010470//regulation of gastrulation;GO:0010634//positive regulation of epithelial cell migration;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0030953//astral microtubule organization;GO:0031023//microtubule organizing center organization;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0034453//microtubule anchoring;GO:0040001//establishment of mitotic spindle localization;GO:0045921//positive regulation of exocytosis;GO:0051128//regulation of cellular component organization;GO:0051294//establishment of spindle orientation;GO:0051301//cell division;GO:0051497//negative regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0090162//establishment of epithelial cell polarity;GO:0090307//mitotic spindle assembly;GO:1903690//negative regulation of wound healing, spreading of epidermal cells;GO:1904261//positive regulation of basement membrane assembly involved in embryonic body morphogenesis"	--
ENSG00000074071	22.676	22.228	24.033	28.197	22.955	26.752	471.25	465.18	368.42	433.78	403.59	404.54	MRPS34	mitochondrial ribosomal protein S34 [Source:HGNC Symbol;Acc:HGNC:16618]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0032543//mitochondrial translation	--
ENSG00000074181	6.802	8.334	7.543	4.62	5.488	5.991	1157	1369	858	598	787	726	NOTCH3	notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Signal transduction;Endocrine system;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04371//Apelin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K20995;K20995;K20995;K20995;K20995;K20995;K20995;K20995;K20995	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0045596//negative regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048663//neuron fate commitment;GO:0048844//artery morphogenesis;GO:0050793//regulation of developmental process;GO:0072104//glomerular capillary formation"	--
ENSG00000074201	51.645	52.133	52.478	50.481	47.045	55.751	1171	1193	886	839	889	923	CLNS1A	chloride nucleotide-sensitive channel 1A [Source:HGNC Symbol;Acc:HGNC:2080]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000387//spliceosomal snRNP assembly;GO:0006397//mRNA processing;GO:0006821//chloride transport;GO:0006884//cell volume homeostasis;GO:0008380//RNA splicing;GO:0043985//histone H4-R3 methylation;GO:0045292//mRNA cis splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000074211	0	0.029	0	0	0.014	0	0	1	0	0	1	0	PPP2R2C	protein phosphatase 2 regulatory subunit Bgamma [Source:HGNC Symbol;Acc:HGNC:9306]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway	K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354	GO:0000159//protein phosphatase type 2A complex;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0050790//regulation of catalytic activity;GO:0070262//peptidyl-serine dephosphorylation	--
ENSG00000074219	16.533	17.304	17.161	13.048	15.03	15.835	721	773	561	421	526	504	TEAD2	TEA domain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11715]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K09448;K09448	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0140552//TEAD-YAP complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0097718//disordered domain specific binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001570//vasculogenesis;GO:0001843//neural tube closure;GO:0003143//embryonic heart tube morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030903//notochord development;GO:0035329//hippo signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048339//paraxial mesoderm development;GO:0048368//lateral mesoderm development;GO:0048568//embryonic organ development;GO:0060548//negative regulation of cell death;GO:0065003//protein-containing complex assembly;GO:0071300//cellular response to retinoic acid;GO:2000736//regulation of stem cell differentiation"	TEA
ENSG00000074266	3.856	4.291	4.499	3.15	4.22	3.703	145	159	120	90	134	103	EED	embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0035098//ESC/E(Z) complex	GO:0001222//transcription corepressor binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0031491//nucleosome binding;GO:0042054//histone methyltransferase activity;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0016571//histone methylation;GO:0021510//spinal cord development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity"	--
ENSG00000074276	0.081	0.046	0.141	0.031	0.041	0	7	4	9	2	3	0	CDHR2	cadherin related family member 2 [Source:HGNC Symbol;Acc:HGNC:18231]	-	-	-	-	GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection;GO:0044214//spanning component of plasma membrane;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030154//cell differentiation;GO:0030855//epithelial cell differentiation;GO:0032532//regulation of microvillus length;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0060243//negative regulation of cell growth involved in contact inhibition;GO:0090675//intermicrovillar adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000074317	0	0	0	0	0.078	0	0	0	0	0	1	0	SNCB	synuclein beta [Source:HGNC Symbol;Acc:HGNC:11140]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016234//inclusion body;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse	GO:0004859//phospholipase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:1903136//cuprous ion binding	GO:0007268//chemical synaptic transmission;GO:0042417//dopamine metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0048488//synaptic vesicle endocytosis;GO:0050808//synapse organization;GO:1901214//regulation of neuron death	--
ENSG00000074319	42.429	40.706	43.149	36.821	34.708	40.399	1350	1295	1014	867	933	928	TSG101	tumor susceptibility 101 [Source:HGNC Symbol;Acc:HGNC:15971]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12183	GO:0000813//ESCRT I complex;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043657//host cell;GO:0070062//extracellular exosome;GO:0090543//Flemming body	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding;GO:0046790//virion binding;GO:0048306//calcium-dependent protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0006464//cellular protein modification process;GO:0006513//protein monoubiquitination;GO:0006858//extracellular transport;GO:0007049//cell cycle;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0008285//negative regulation of cell population proliferation;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0040008//regulation of growth;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0043405//regulation of MAP kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046755//viral budding;GO:0046907//intracellular transport;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0075733//intracellular transport of virus;GO:0097352//autophagosome maturation;GO:1903543//positive regulation of exosomal secretion;GO:1903551//regulation of extracellular exosome assembly;GO:1903774//positive regulation of viral budding via host ESCRT complex;GO:1990182//exosomal secretion;GO:2000397//positive regulation of ubiquitin-dependent endocytosis"	--
ENSG00000074356	5.711	5.135	13.789	20.054	5.046	5.516	696	626	467	464	559	469	NCBP3	nuclear cap binding subunit 3 [Source:HGNC Symbol;Acc:HGNC:24612]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005845//mRNA cap binding complex;GO:0005846//nuclear cap binding complex;GO:0016607//nuclear speck;GO:0034518//RNA cap binding complex	GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006408//snRNA export from nucleus;GO:0016246//RNA interference;GO:0042789//mRNA transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:0051607//defense response to virus	--
ENSG00000074370	0.593	0.61	0.389	0.555	0.612	0.508	49	57	28	40	50	36	ATP2A3	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Cardiovascular disease;Circulatory system;Neurodegenerative disease;Endocrine system;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031090//organelle membrane;GO:0031095//platelet dense tubular network membrane;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0015085//calcium ion transmembrane transporter activity;GO:0015662//P-type ion transporter activity;GO:0016887//ATP hydrolysis activity;GO:0030899//calcium-dependent ATPase activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0034220//ion transmembrane transport;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070588//calcium ion transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1900121//negative regulation of receptor binding;GO:1903515//calcium ion transport from cytosol to endoplasmic reticulum;GO:1903779//regulation of cardiac conduction	--
ENSG00000074410	0.288	0.248	0.171	0.155	0.189	0.099	22	16	12	7	10	5	CA12	carbonic anhydrase 12 [Source:HGNC Symbol;Acc:HGNC:1371]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process;GO:0055064//chloride ion homeostasis	--
ENSG00000074416	6.861	6.983	6.883	4.696	5.883	4.989	605	620	449	306	439	320	MGLL	monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038]	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Environmental adaptation;Nervous system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04723//Retrograde endocannabinoid signaling;ko00561//Glycerolipid metabolism;ko04923//Regulation of lipolysis in adipocytes	K01054;K01054;K01054;K01054;K01054	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0047372//acylglycerol lipase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006954//inflammatory response;GO:0009966//regulation of signal transduction;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019433//triglyceride catabolic process;GO:0046464//acylglycerol catabolic process;GO:0050727//regulation of inflammatory response;GO:0051930//regulation of sensory perception of pain;GO:0052651//monoacylglycerol catabolic process;GO:2000124//regulation of endocannabinoid signaling pathway	--
ENSG00000074527	17.395	16.111	14.897	14.763	13.883	15.29	1261	1179	810	777	859	782	NTN4	netrin 4 [Source:HGNC Symbol;Acc:HGNC:13658]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06845	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0043256//laminin complex	GO:0005515//protein binding;GO:0043237//laminin-1 binding	GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016322//neuron remodeling;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0060668//regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling;GO:0070831//basement membrane assembly	--
ENSG00000074582	8.518	8.799	8.675	10.509	9.948	8.514	236	253	199	205	221	187	BCS1L	"BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone [Source:HGNC Symbol;Acc:HGNC:1020]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007005//mitochondrion organization;GO:0032979//protein insertion into mitochondrial inner membrane from matrix;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0034551//mitochondrial respiratory chain complex III assembly	--
ENSG00000074590	3.835	3.549	2.602	2.821	3.358	2.492	447	425	229	249	338	216	NUAK1	NUAK family kinase 1 [Source:HGNC Symbol;Acc:HGNC:14311]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007155//cell adhesion;GO:0016310//phosphorylation;GO:0030155//regulation of cell adhesion;GO:0035507//regulation of myosin-light-chain-phosphatase activity;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0042149//cellular response to glucose starvation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:2000772//regulation of cellular senescence	--
ENSG00000074603	8.471	8.778	6.954	5.713	6.578	7.714	1135	966	676	600	715	722	DPP8	dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006955//immune response	--
ENSG00000074621	1.512	2.323	2.575	2.144	1.427	1.238	161	189	133	104	105	95	SLC24A1	solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975]	Organismal Systems	Sensory system	ko04744//Phototransduction	K13749	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019867//outer membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043025//neuronal cell body;GO:0044214//spanning component of plasma membrane	"GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007601//visual perception;GO:0009642//response to light intensity;GO:0035725//sodium ion transmembrane transport;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0070588//calcium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098703//calcium ion import across plasma membrane	--
ENSG00000074657	33.697	34.25	29.274	23.444	24.009	31.624	2541	2472	1764	1297	1718	1705	ZNF532	zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000074660	0.352	0.532	0.668	0.699	0.732	0.674	25	38	33	35	44	34	SCARF1	scavenger receptor class F member 1 [Source:HGNC Symbol;Acc:HGNC:16820]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding	GO:0006707//cholesterol catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0007155//cell adhesion;GO:0010976//positive regulation of neuron projection development;GO:0016322//neuron remodeling;GO:0016358//dendrite development;GO:0048680//positive regulation of axon regeneration	--
ENSG00000074695	44.504	36.809	36.468	31.585	33.016	36.028	4453	3702	2695	2341	2791	2623	LMAN1	"lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10080	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030017//sarcomere;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0007596//blood coagulation;GO:0010638//positive regulation of organelle organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:1903215//negative regulation of protein targeting to mitochondrion	--
ENSG00000074696	80.933	75.331	78.335	62.481	59.442	67.612	5367	5046	3839	3005	3335	3271	HACD3	3-hydroxyacyl-CoA dehydratase 3 [Source:HGNC Symbol;Acc:HGNC:24175]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10703;K10703;K10703;K10703	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031965//nuclear membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007254//JNK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0016601//Rac protein signal transduction;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0045070//positive regulation of viral genome replication;GO:0046726//positive regulation by virus of viral protein levels in host cell;GO:0050790//regulation of catalytic activity	--
ENSG00000074706	0.166	0.058	0.132	0.066	0.085	0.089	23	3.98	5.49	6.77	9.96	9	IPCEF1	interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding	GO:0006979//response to oxidative stress;GO:0015671//oxygen transport;GO:0098869//cellular oxidant detoxification	--
ENSG00000074755	17.893	18.025	18.912	17.501	17.763	16.221	3875	3964	2964	2662	3292	2537	ZZEF1	zinc finger ZZ-type and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29027]	-	-	-	-	-	GO:0003713//transcription coactivator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0070577//lysine-acetylated histone binding	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000074771	0	0	0	0	0	0	0	0	0	0	0	0	NOX3	NADPH oxidase 3 [Source:HGNC Symbol;Acc:HGNC:7890]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043020//NADPH oxidase complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity	GO:0001659//temperature homeostasis;GO:0006952//defense response;GO:0009590//detection of gravity;GO:0009629//response to gravity;GO:0042554//superoxide anion generation;GO:0048840//otolith development	--
ENSG00000074800	569.634	584.872	617.254	706.814	658.243	629.642	20644	21125	16515	18940	20158	16561	ENO1	enolase 1 [Source:HGNC Symbol;Acc:HGNC:3350]	Metabolism;Environmental Information Processing;Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Signal transduction;Global and overview maps;Folding, sorting and degradation;Global and overview maps;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K01689;K01689;K01689;K01689;K01689;K01689	GO:0000015//phosphopyruvate hydratase complex;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0009986//cell surface;GO:0016020//membrane;GO:0031430//M band;GO:0070062//extracellular exosome	"GO:0000287//magnesium ion binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0004634//phosphopyruvate hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0051020//GTPase binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006096//glycolytic process;GO:0009615//response to virus;GO:0010756//positive regulation of plasminogen activation;GO:0030308//negative regulation of cell growth;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045933//positive regulation of muscle contraction;GO:0061621//canonical glycolysis;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000074803	0.062	0.051	0.12	0.083	0.086	0.083	6	5	6	6	7	5	SLC12A1	solute carrier family 12 member 1 [Source:HGNC Symbol;Acc:HGNC:10910]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0008511//sodium:potassium:chloride symporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006884//cell volume homeostasis;GO:0015698//inorganic anion transport;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000074842	39.958	41.441	36.931	46.22	41.173	41.667	742	762	524	630	636	552	MYDGF	myeloid derived growth factor [Source:HGNC Symbol;Acc:HGNC:16948]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006915//apoptotic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000074855	2.346	2.158	2.344	2.857	2.729	3.117	191	189	150	162	195	197	ANO8	anoctamin 8 [Source:HGNC Symbol;Acc:HGNC:29329]	-	-	-	-	GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005229//intracellular calcium activated chloride channel activity	GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000074935	2.802	2.931	2.354	3.469	2.884	3.84	116	123	73	89	100	98	TUBE1	tubulin epsilon 1 [Source:HGNC Symbol;Acc:HGNC:20775]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0007098//centrosome cycle	--
ENSG00000074964	23.834	22.618	23.662	21.839	22.936	24.524	1979	1873	1442	1338	1609	1481	ARHGEF10L	Rho guanine nucleotide exchange factor 10 like [Source:HGNC Symbol;Acc:HGNC:25540]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0030036//actin cytoskeleton organization;GO:0032933//SREBP signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051496//positive regulation of stress fiber assembly	--
ENSG00000074966	0.034	0	0	0	0.238	0.072	1	0	0	0	6	2	TXK	TXK tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12434]	Organismal Systems	Immune system	ko04670//Leukocyte transendothelial migration	K08016	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001819//positive regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007202//activation of phospholipase C activity;GO:0007229//integrin-mediated signaling pathway;GO:0010468//regulation of gene expression;GO:0010543//regulation of platelet activation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032729//positive regulation of interferon-gamma production;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042246//tissue regeneration;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway	--
ENSG00000075035	0.398	0.544	0.736	0.565	0.414	0.591	42	57	51	41	36	12	WSCD2	WSC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29117]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000075043	0	0	0	0	0	0	0	0	0	0	0	0	KCNQ2	potassium voltage-gated channel subfamily Q member 2 [Source:HGNC Symbol;Acc:HGNC:6296]	Organismal Systems	Nervous system	ko04725//Cholinergic synapse	K04927	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033268//node of Ranvier;GO:0043194//axon initial segment;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0030506//ankyrin binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000075073	0.249	0.028	0	0.15	0.066	0.038	9	1	0	4	2	1	TACR2	tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04223;K04223	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036126//sperm flagellum;GO:0061827//sperm head;GO:0097225//sperm midpiece	GO:0004930//G protein-coupled receptor activity;GO:0004995//tachykinin receptor activity;GO:0005515//protein binding;GO:0016497//substance K receptor activity	"GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007217//tachykinin receptor signaling pathway;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission;GO:0014827//intestine smooth muscle contraction;GO:0033685//negative regulation of luteinizing hormone secretion;GO:0035106//operant conditioning;GO:0043117//positive regulation of vascular permeability;GO:0043270//positive regulation of ion transport;GO:0045987//positive regulation of smooth muscle contraction;GO:0051602//response to electrical stimulus;GO:0070459//prolactin secretion;GO:0070472//regulation of uterine smooth muscle contraction;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:1902093//positive regulation of flagellated sperm motility"	--
ENSG00000075089	9.199	7.725	7.512	5.465	7.004	8.226	319	282	202	147	214	215	ACTR6	actin related protein 6 [Source:HGNC Symbol;Acc:HGNC:24025]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0031491//nucleosome binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0043486//histone exchange"	--
ENSG00000075131	2.148	2.552	2.898	2.569	2.584	2.949	56	71	60	49	63	54	TIPIN	TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031298//replication fork protection complex	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0000076//DNA replication checkpoint signaling;GO:0000077//DNA damage checkpoint signaling;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0009411//response to UV;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0043111//replication fork arrest;GO:0044770//cell cycle phase transition;GO:0048478//replication fork protection;GO:0051301//cell division	--
ENSG00000075142	35.459	35.077	39.912	36.764	33.105	40.375	898	872	639	652	673	711	SRI	sorcin [Source:HGNC Symbol;Acc:HGNC:11292]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031982//vesicle;GO:0033017//sarcoplasmic reticulum membrane;GO:0042584//chromaffin granule membrane;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0140297//DNA-binding transcription factor binding	GO:0001508//action potential;GO:0006816//calcium ion transport;GO:0006880//intracellular sequestering of iron ion;GO:0006942//regulation of striated muscle contraction;GO:0007165//signal transduction;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0008016//regulation of heart contraction;GO:0010459//negative regulation of heart rate;GO:0010649//regulation of cell communication by electrical coupling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051924//regulation of calcium ion transport;GO:0055118//negative regulation of cardiac muscle contraction;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0086004//regulation of cardiac muscle cell contraction;GO:1901077//regulation of relaxation of muscle;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:2000678//negative regulation of transcription regulatory region DNA binding	--
ENSG00000075151	26.655	22.221	20.716	14.633	17.486	19.461	2973	2560	1695	1223	1672	1545	EIF4G3	eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]	Human Diseases	Cardiovascular disease	ko05416//Viral myocarditis	K03260	GO:0005829//cytosol;GO:0016281//eukaryotic translation initiation factor 4F complex	"GO:0000339//RNA cap binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation	--
ENSG00000075188	11.882	14.391	10.977	9.643	10.285	12.651	268	312	183	160	198	209	NUP37	nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14302;K14302	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring"	GO:0005515//protein binding	GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051301//cell division	--
ENSG00000075213	4.187	5.54	2.919	2.144	2.854	2.497	386	364	173	150	205	168	SEMA3A	semaphorin 3A [Source:HGNC Symbol;Acc:HGNC:10723]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0030425//dendrite	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0038191//neuropilin binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0010977//negative regulation of neuron projection development;GO:0021675//nerve development;GO:0021772//olfactory bulb development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0046330//positive regulation of JNK cascade;GO:0048485//sympathetic nervous system development;GO:0048841//regulation of axon extension involved in axon guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048846//axon extension involved in axon guidance;GO:0048880//sensory system development;GO:0050919//negative chemotaxis;GO:0060385//axonogenesis involved in innervation;GO:0061549//sympathetic ganglion development;GO:0071526//semaphorin-plexin signaling pathway;GO:0097490//sympathetic neuron projection extension;GO:0097491//sympathetic neuron projection guidance;GO:0150020//basal dendrite arborization;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:2001224//positive regulation of neuron migration	--
ENSG00000075218	0.582	0.643	0.853	1.025	0.937	0.889	36	40	39	47	49	40	GTSE1	G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10129	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	"GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007017//microtubule-based process"	--
ENSG00000075223	57.045	44.818	36.733	33.002	37.095	38.411	4381	3448	2239	1881	2424	2166	SEMA3C	semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0001756//somitogenesis;GO:0001974//blood vessel remodeling;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003350//pulmonary myocardium development;GO:0006955//immune response;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007507//heart development;GO:0009410//response to xenobiotic stimulus;GO:0009791//post-embryonic development;GO:0021915//neural tube development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0060174//limb bud formation;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0071526//semaphorin-plexin signaling pathway;GO:0140074//cardiac endothelial to mesenchymal transition;GO:1905312//positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	--
ENSG00000075234	14.771	14.641	14.292	16.427	16.797	15.606	709	670	550	532	647	514	TTC38	tetratricopeptide repeat domain 38 [Source:HGNC Symbol;Acc:HGNC:26082]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000075239	63.581	60.619	62.242	64.229	55.667	59.235	2020	1931	1459	1506	1486	1366	ACAT1	acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Metabolism of terpenoids and polyketides	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko04975//Fat digestion and absorption;ko00630//Glyoxylate and dicarboxylate metabolism;ko00650//Butanoate metabolism;ko00900//Terpenoid backbone biosynthesis"	K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome	"GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0016453//C-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0019899//enzyme binding;GO:0030955//potassium ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0120225//coenzyme A binding"	GO:0001889//liver development;GO:0006085//acetyl-CoA biosynthetic process;GO:0006550//isoleucine catabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0007420//brain development;GO:0009725//response to hormone;GO:0014070//response to organic cyclic compound;GO:0015936//coenzyme A metabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0034435//cholesterol esterification;GO:0042594//response to starvation;GO:0046356//acetyl-CoA catabolic process;GO:0046952//ketone body catabolic process;GO:0060612//adipose tissue development;GO:0072229//metanephric proximal convoluted tubule development;GO:1902224//ketone body metabolic process;GO:1902860//propionyl-CoA biosynthetic process	--
ENSG00000075240	47.552	41.583	47.231	41.883	61.46	72.884	2420	2292	1834	1680	1892	2175	GRAMD4	GRAM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:29113]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000075275	7.843	9.182	7.761	7.573	8.437	7.682	1740	1883	1220	1154	1568	1076	CELSR1	cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding	"GO:0001736//establishment of planar polarity;GO:0001764//neuron migration;GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007417//central nervous system development;GO:0007626//locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0032956//regulation of actin cytoskeleton organization;GO:0042060//wound healing;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0042472//inner ear morphogenesis;GO:0045176//apical protein localization;GO:0048105//establishment of body hair planar orientation;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060488//orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis;GO:0060489//planar dichotomous subdivision of terminal units involved in lung branching morphogenesis;GO:0060490//lateral sprouting involved in lung morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0090251//protein localization involved in establishment of planar polarity;GO:0098609//cell-cell adhesion"	--
ENSG00000075290	0	0.067	0.03	0.03	0.027	0	0	3	1	1	1	0	WNT8B	Wnt family member 8B [Source:HGNC Symbol;Acc:HGNC:12789]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714;K00714	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity	GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0007369//gastrulation;GO:0007399//nervous system development;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0045165//cell fate commitment;GO:0048263//determination of dorsal identity;GO:0060070//canonical Wnt signaling pathway;GO:0071300//cellular response to retinoic acid	--
ENSG00000075292	11.862	7.087	6.517	5.314	6.313	6.123	1184	718	506	356	510	488	ZNF638	zinc finger protein 638 [Source:HGNC Symbol;Acc:HGNC:17894]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008380//RNA splicing	--
ENSG00000075303	3.919	4.084	4.02	3.505	3.613	5.271	321	269	204	186	236	278	SLC25A40	solute carrier family 25 member 40 [Source:HGNC Symbol;Acc:HGNC:29680]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0055085//transmembrane transport;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000075336	7.649	6.925	6.376	6.027	4.975	5.826	405	371	241	234	251	229	TIMM21	translocase of inner mitochondrial membrane 21 [Source:HGNC Symbol;Acc:HGNC:25010]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000075340	0.342	0.448	0.366	1.288	0.551	0.515	34	45.01	33	52	50	33	ADD2	adducin 2 [Source:HGNC Symbol;Acc:HGNC:244]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008290//F-actin capping protein complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0044853//plasma membrane raft	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005516//calmodulin binding;GO:0019901//protein kinase binding;GO:0030507//spectrin binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding	GO:0007416//synapse assembly;GO:0030036//actin cytoskeleton organization;GO:0030097//hemopoiesis;GO:0032092//positive regulation of protein binding;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0051016//barbed-end actin filament capping;GO:0051017//actin filament bundle assembly;GO:0065003//protein-containing complex assembly	--
ENSG00000075388	0	0	0	0	0	0	0	0	0	0	0	0	FGF4	fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0001502//cartilage condensation;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010463//mesenchymal cell proliferation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030334//regulation of cell migration;GO:0035116//embryonic hindlimb morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051781//positive regulation of cell division;GO:0060363//cranial suture morphogenesis;GO:0060561//apoptotic process involved in morphogenesis;GO:0060591//chondroblast differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000544//regulation of endothelial cell chemotaxis to fibroblast growth factor	--
ENSG00000075391	9.31	7.933	7.33	5.283	8.34	7.68	1680	1403	982	698	1086	965	RASAL2	RAS protein activator like 2 [Source:HGNC Symbol;Acc:HGNC:9874]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17633	GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0002021//response to dietary excess;GO:0007165//signal transduction;GO:0009749//response to glucose;GO:0010467//gene expression;GO:0035264//multicellular organism growth;GO:0043087//regulation of GTPase activity;GO:0060612//adipose tissue development;GO:2000257//regulation of protein activation cascade	--
ENSG00000075399	6.008	5.913	6.037	7.19	7.242	6.279	273	247	246	247	285	240	VPS9D1	VPS9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13526]	-	-	-	-	GO:0005829//cytosol;GO:0030139//endocytic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0015986//ATP synthesis coupled proton transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000075407	1.989	1.063	1.101	0.821	1.296	1.582	311	168	126	97	176	176	ZNF37A	zinc finger protein 37A [Source:HGNC Symbol;Acc:HGNC:13102]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000075413	23.241	19.536	22.209	16.51	18.088	21.544	1349	1123	919	727	857	876	MARK3	microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032092//positive regulation of protein binding;GO:0035331//negative regulation of hippo signaling;GO:0035556//intracellular signal transduction;GO:0036289//peptidyl-serine autophosphorylation	--
ENSG00000075415	400.129	396.005	406.214	439.798	405.314	390.242	7557	7596	5714	6123	6532	5426	SLC25A3	solute carrier family 25 member 3 [Source:HGNC Symbol;Acc:HGNC:10989]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0070062//extracellular exosome	GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015317//phosphate:proton symporter activity;GO:0044877//protein-containing complex binding	GO:0035435//phosphate ion transmembrane transport;GO:1902600//proton transmembrane transport;GO:1990547//mitochondrial phosphate ion transmembrane transport	--
ENSG00000075420	26.491	24.095	18.46	12.787	16.05	16.386	3062	2797	1558	1171	1552	1269	FNDC3B	fibronectin type III domain containing 3B [Source:HGNC Symbol;Acc:HGNC:24670]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000075426	17.248	17.135	14.584	13.712	15.892	14.791	2108	2097	1333	1117	1532	1296	FOSL2	"FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798]"	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K09030	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0003334//keratinocyte development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008219//cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation"	TF_bZIP
ENSG00000075429	0	0	0	0	0.005	0	0	0	0	0	1	0	CACNG5	calcium voltage-gated channel auxiliary subunit gamma 5 [Source:HGNC Symbol;Acc:HGNC:1409]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04870;K04870;K04870;K04870;K04870;K04870;K04870	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005245//voltage-gated calcium channel activity;GO:0015075//ion transmembrane transporter activity;GO:0016247//channel regulator activity	"GO:0006816//calcium ion transport;GO:0019226//transmission of nerve impulse;GO:0034220//ion transmembrane transport;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099590//neurotransmitter receptor internalization;GO:2000311//regulation of AMPA receptor activity"	--
ENSG00000075461	2.368	2.958	2.277	2.398	3.138	2.256	176	221	125	132	197	122	CACNG4	calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04869;K04869;K04869;K04869;K04869;K04869;K04869	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0036477//somatodendritic compartment;GO:0044297//cell body;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity;GO:0035255//ionotropic glutamate receptor binding	"GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0019226//transmission of nerve impulse;GO:0034765//regulation of ion transmembrane transport;GO:0042220//response to cocaine;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099590//neurotransmitter receptor internalization;GO:2000311//regulation of AMPA receptor activity;GO:2000969//positive regulation of AMPA receptor activity"	--
ENSG00000075539	8.749	6.298	6.007	4.022	5.102	4.574	1216	836	634	406	567	473	FRYL	FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]	-	-	-	-	GO:0005938//cell cortex;GO:0030427//site of polarized growth	GO:0005515//protein binding	GO:0000902//cell morphogenesis;GO:0031175//neuron projection development	--
ENSG00000075568	7.209	6.671	6.059	4.866	6.456	5.33	1002	932	622	501	695	539	TMEM131	transmembrane protein 131 [Source:HGNC Symbol;Acc:HGNC:30366]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000075618	20.937	22.793	23.908	29.457	26.77	26.586	1209	1313	1005	1260	1306	1112	FSCN1	fascin actin-bundling protein 1 [Source:HGNC Symbol;Acc:HGNC:11148]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K23551	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030426//growth cone;GO:0031253//cell projection membrane;GO:0042995//cell projection;GO:0044393//microspike;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007043//cell-cell junction assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0010592//positive regulation of lamellipodium assembly;GO:0016477//cell migration;GO:0030035//microspike assembly;GO:0030036//actin cytoskeleton organization;GO:0030046//parallel actin filament bundle assembly;GO:0032534//regulation of microvillus assembly;GO:0032956//regulation of actin cytoskeleton organization;GO:0035089//establishment of apical/basal cell polarity;GO:0048870//cell motility;GO:0051017//actin filament bundle assembly;GO:0051491//positive regulation of filopodium assembly;GO:0071803//positive regulation of podosome assembly;GO:0090091//positive regulation of extracellular matrix disassembly	--
ENSG00000075624	1250.266	1336.594	1310.506	1435.083	1478.377	1172.266	46647	50010	36180	39579	46494	31793	ACTB	actin beta [Source:HGNC Symbol;Acc:HGNC:132]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cell motility;Signal transduction;Transport and catabolism;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Infectious disease: viral;Cellular community - eukaryotes;Cancer: specific types;Cardiovascular disease;Signal transduction;Endocrine system;Cell growth and death;Cardiovascular disease;Cardiovascular disease;Immune system;Endocrine system;Immune system;Cardiovascular disease;Infectious disease: bacterial;Cardiovascular disease;Digestive system;Cellular community - eukaryotes;Infectious disease: bacterial	ko05014//Amyotrophic lateral sclerosis;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04714//Thermogenesis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05164//Influenza A;ko04530//Tight junction;ko05225//Hepatocellular carcinoma;ko05414//Dilated cardiomyopathy;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko05416//Viral myocarditis;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04670//Leukocyte transendothelial migration;ko05410//Hypertrophic cardiomyopathy;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04971//Gastric acid secretion;ko04520//Adherens junction;ko05110//Vibrio cholerae infection	K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0030027//lamellipodium;GO:0030424//axon;GO:0030863//cortical cytoskeleton;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043296//apical junction complex;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0070160//tight junction;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0072562//blood microparticle;GO:0097433//dense body;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098871//postsynaptic actin cytoskeleton;GO:0098978//glutamatergic synapse;GO:0140092//bBAF complex;GO:0140288//GBAF complex;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0030957//Tat protein binding;GO:0031492//nucleosomal DNA binding;GO:0042802//identical protein binding;GO:0048156//tau protein binding;GO:0050998//nitric-oxide synthase binding;GO:0098973//structural constituent of postsynaptic actin cytoskeleton	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001738//morphogenesis of a polarized epithelium;GO:0001895//retina homeostasis;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0016573//histone acetylation;GO:0021762//substantia nigra development;GO:0022898//regulation of transmembrane transporter activity;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0032091//negative regulation of protein binding;GO:0034333//adherens junction assembly;GO:0035633//maintenance of blood-brain barrier;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045176//apical protein localization;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048488//synaptic vesicle endocytosis;GO:0048870//cell motility;GO:0051621//regulation of norepinephrine uptake;GO:0051623//positive regulation of norepinephrine uptake;GO:0051726//regulation of cell cycle;GO:0070316//regulation of G0 to G1 transition;GO:0070527//platelet aggregation;GO:0071896//protein localization to adherens junction;GO:0072749//cellular response to cytochalasin B;GO:0098974//postsynaptic actin cytoskeleton organization;GO:0150111//regulation of transepithelial transport;GO:1902459//positive regulation of stem cell population maintenance;GO:1903076//regulation of protein localization to plasma membrane;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000779//regulation of double-strand break repair;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000075643	0.156	0.163	0.053	0.084	0.212	0.139	20	21	5	8	23	13	MOCOS	molybdenum cofactor sulfurase [Source:HGNC Symbol;Acc:HGNC:18234]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K15631;K15631	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008265//Mo-molybdopterin cofactor sulfurase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0030151//molybdenum ion binding;GO:0030170//pyridoxal phosphate binding;GO:0102867//molybdenum cofactor sulfurtransferase activity	GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0032324//molybdopterin cofactor biosynthetic process;GO:0043545//molybdopterin cofactor metabolic process	--
ENSG00000075651	4.837	3.953	3.629	4.162	4.822	5.037	495	449	329	343	440	378	PLD1	phospholipase D1 [Source:HGNC Symbol;Acc:HGNC:9067]	Metabolism;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Transport and catabolism;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Immune system;Signal transduction;Nervous system;Endocrine system;Cancer: overview;Lipid metabolism;Endocrine system;Cancer: specific types;Lipid metabolism	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04024//cAMP signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04071//Sphingolipid signaling pathway;ko04724//Glutamatergic synapse;ko04928//Parathyroid hormone synthesis, secretion and action;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko05212//Pancreatic cancer;ko00565//Ether lipid metabolism"	K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0031902//late endosome membrane;GO:0035579//specific granule membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070821//tertiary granule membrane;GO:0098981//cholinergic synapse	GO:0003824//catalytic activity;GO:0004630//phospholipase D activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035091//phosphatidylinositol binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006935//chemotaxis;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0016042//lipid catabolic process;GO:0032534//regulation of microvillus assembly;GO:0045727//positive regulation of translation;GO:0048017//inositol lipid-mediated signaling;GO:0048870//cell motility;GO:0098693//regulation of synaptic vesicle cycle	--
ENSG00000075673	0	0	0	0	0	0	0	0	0	0	0	0	ATP12A	ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00190//Oxidative phosphorylation	K01544;K01544	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005889//potassium:proton exchanging ATPase complex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0008900//P-type potassium:proton transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0006885//regulation of pH;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0030007//cellular potassium ion homeostasis;GO:0036376//sodium ion export across plasma membrane;GO:0055075//potassium ion homeostasis;GO:1902600//proton transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000075702	0.922	0.559	0.437	0.944	0.551	0.522	46	35	30	29	30	27	WDR62	WD repeat domain 62 [Source:HGNC Symbol;Acc:HGNC:24502]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0002052//positive regulation of neuroblast proliferation;GO:0007052//mitotic spindle organization;GO:0007099//centriole replication;GO:0007399//nervous system development;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0045664//regulation of neuron differentiation;GO:0046605//regulation of centrosome cycle;GO:2001224//positive regulation of neuron migration	--
ENSG00000075711	30.58	23.276	25.152	19.328	20.491	24.199	2187	1805	1430	1088	1305	1361	DLG1	discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Signal transduction;Immune system	ko05165//Human papillomavirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04660//T cell receptor signaling pathway	K12076;K12076;K12076;K12076;K12076;K12076	GO:0001772//immunological synapse;GO:0005604//basement membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0014069//postsynaptic density;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0031253//cell projection membrane;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0035748//myelin sheath abaxonal region;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0043219//lateral loop;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0097060//synaptic membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0004385//guanylate kinase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0015459//potassium channel regulator activity;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity;GO:0097016//L27 domain binding;GO:0098919//structural constituent of postsynaptic density	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001771//immunological synapse formation;GO:0001935//endothelial cell proliferation;GO:0002088//lens development in camera-type eye;GO:0006470//protein dephosphorylation;GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007268//chemical synaptic transmission;GO:0008104//protein localization;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0030432//peristalsis;GO:0030838//positive regulation of actin filament polymerization;GO:0030866//cortical actin cytoskeleton organization;GO:0030953//astral microtubule organization;GO:0031503//protein-containing complex localization;GO:0031579//membrane raft organization;GO:0031641//regulation of myelination;GO:0032147//activation of protein kinase activity;GO:0042110//T cell activation;GO:0042130//negative regulation of T cell proliferation;GO:0042391//regulation of membrane potential;GO:0042982//amyloid precursor protein metabolic process;GO:0043113//receptor clustering;GO:0043268//positive regulation of potassium ion transport;GO:0043622//cortical microtubule organization;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process;GO:0048608//reproductive structure development;GO:0048704//embryonic skeletal system morphogenesis;GO:0048729//tissue morphogenesis;GO:0048745//smooth muscle tissue development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051660//establishment of centrosome localization;GO:0051898//negative regulation of protein kinase B signaling;GO:0060022//hard palate development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070830//bicellular tight junction assembly;GO:0072659//protein localization to plasma membrane;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:0099562//maintenance of postsynaptic density structure;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1902305//regulation of sodium ion transmembrane transport;GO:1902473//regulation of protein localization to synapse;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903286//regulation of potassium ion import;GO:1903753//negative regulation of p38MAPK cascade;GO:1903760//regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:1903764//regulation of potassium ion export across plasma membrane;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000075785	143.932	139.383	143.93	140.404	139.833	153.959	6128	5940	4410	4311	4983	4709	RAB7A	"RAB7A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9788]"	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Transport and catabolism;Infectious disease: parasitic;Transport and catabolism;Transport and catabolism	ko05132//Salmonella infection;ko04144//Endocytosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05146//Amoebiasis;ko04140//Autophagy - animal;ko04137//Mitophagy - animal	K07897;K07897;K07897;K07897;K07897;K07897;K07897	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0030904//retromer complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032419//extrinsic component of lysosome membrane;GO:0033162//melanosome membrane;GO:0034045//phagophore assembly site membrane;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0097208//alveolar lamellar body;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0031267//small GTPase binding;GO:1905394//retromer complex binding	"GO:0000045//autophagosome assembly;GO:0006622//protein targeting to lysosome;GO:0006629//lipid metabolic process;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0007174//epidermal growth factor catabolic process;GO:0008333//endosome to lysosome transport;GO:0009617//response to bacterium;GO:0015031//protein transport;GO:0016042//lipid catabolic process;GO:0019076//viral release from host cell;GO:0022615//protein to membrane docking;GO:0042147//retrograde transport, endosome to Golgi;GO:0045022//early endosome to late endosome transport;GO:0045453//bone resorption;GO:0045732//positive regulation of protein catabolic process;GO:0046907//intracellular transport;GO:0048524//positive regulation of viral process;GO:0051650//establishment of vesicle localization;GO:0061724//lipophagy;GO:0090382//phagosome maturation;GO:0090383//phagosome acidification;GO:0090385//phagosome-lysosome fusion;GO:0099638//endosome to plasma membrane protein transport;GO:1903542//negative regulation of exosomal secretion;GO:1903543//positive regulation of exosomal secretion;GO:1905366//negative regulation of intralumenal vesicle formation"	--
ENSG00000075790	10.847	11.054	12.9	6.857	10.678	8.918	427.01	343.48	291.56	219.34	263.45	231.41	BCAP29	B cell receptor associated protein 29 [Source:HGNC Symbol;Acc:HGNC:24131]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0001649//osteoblast differentiation;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006915//apoptotic process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0070973//protein localization to endoplasmic reticulum exit site	--
ENSG00000075826	0.654	0.442	0.845	0.979	1.216	1.448	64.94	43.9	62	69.65	102.72	103.94	SEC31B	"SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14005	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030120//vesicle coat;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0070971//endoplasmic reticulum exit site	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000075856	12.537	14.457	14.741	12.056	14.746	12.421	1003	1060	820	709	816	694	SART3	"spliceosome associated factor 3, U4/U6 recycling protein [Source:HGNC Symbol;Acc:HGNC:16860]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005691//U6atac snRNP;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0061574//ASAP complex;GO:0071001//U4/U6 snRNP	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0030621//U4 snRNA binding;GO:0030624//U6atac snRNA binding;GO:0042393//histone binding;GO:1990381//ubiquitin-specific protease binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0000902//cell morphogenesis;GO:0006334//nucleosome assembly;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0048872//homeostasis of number of cells;GO:0071425//hematopoietic stem cell proliferation;GO:1903586//positive regulation of histone deubiquitination"	--
ENSG00000075884	0	0	0	0	0	0	0	0	0	0	0	0	ARHGAP15	Rho GTPase activating protein 15 [Source:HGNC Symbol;Acc:HGNC:21030]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0043087//regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000075886	0	0	0	0.086	0	0.087	0	0	0	2	0	2	TUBA3D	tubulin alpha 3d [Source:HGNC Symbol;Acc:HGNC:24071]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process	--
ENSG00000075891	0	0	0	0	0	0	0	0	0	0	0	0	PAX2	paired box 2 [Source:HGNC Symbol;Acc:HGNC:8616]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005815//microtubule organizing center;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0034451//centriolar satellite	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001655//urogenital system development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001709//cell fate determination;GO:0001823//mesonephros development;GO:0001843//neural tube closure;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0003406//retinal pigment epithelium development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0007501//mesodermal cell fate specification;GO:0007568//aging;GO:0007601//visual perception;GO:0008284//positive regulation of cell population proliferation;GO:0010001//glial cell differentiation;GO:0021554//optic nerve development;GO:0021631//optic nerve morphogenesis;GO:0021633//optic nerve structural organization;GO:0021650//vestibulocochlear nerve formation;GO:0030154//cell differentiation;GO:0031667//response to nutrient levels;GO:0035566//regulation of metanephros size;GO:0035799//ureter maturation;GO:0039003//pronephric field specification;GO:0042472//inner ear morphogenesis;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043491//protein kinase B signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048793//pronephros development;GO:0048854//brain morphogenesis;GO:0048856//anatomical structure development;GO:0048863//stem cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060231//mesenchymal to epithelial transition;GO:0061360//optic chiasma development;GO:0070301//cellular response to hydrogen peroxide;GO:0071300//cellular response to retinoic acid;GO:0071333//cellular response to glucose stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072075//metanephric mesenchyme development;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072179//nephric duct formation;GO:0072189//ureter development;GO:0072205//metanephric collecting duct development;GO:0072207//metanephric epithelium development;GO:0072221//metanephric distal convoluted tubule development;GO:0072289//metanephric nephron tubule formation;GO:0072300//positive regulation of metanephric glomerulus development;GO:0072305//negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0072593//reactive oxygen species metabolic process;GO:0090102//cochlea development;GO:0090103//cochlea morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development;GO:1900215//negative regulation of apoptotic process involved in metanephric collecting duct development;GO:1900218//negative regulation of apoptotic process involved in metanephric nephron tubule development;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000594//positive regulation of metanephric DCT cell differentiation;GO:2000597//positive regulation of optic nerve formation"	PAX
ENSG00000075914	9.392	10.587	11.59	11.368	9.474	10.302	203	230	185	182	173	162	EXOSC7	exosome component 7 [Source:HGNC Symbol;Acc:HGNC:28112]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12589	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101019//nucleolar exosome (RNase complex);GO:1902494//catalytic complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034473//U1 snRNA 3'-end processing;GO:0034475//U4 snRNA 3'-end processing;GO:0034476//U5 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0051252//regulation of RNA metabolic process;GO:0071028//nuclear mRNA surveillance;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071042//nuclear polyadenylation-dependent mRNA catabolic process"	--
ENSG00000075945	14.207	13.222	13.98	10.465	11.533	13.204	872	815	633	472	597	589	KIFAP3	kinesin associated protein 3 [Source:HGNC Symbol;Acc:HGNC:17060]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005876//spindle microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0016939//kinesin II complex;GO:0032391//photoreceptor connecting cilium;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0097542//ciliary tip;GO:1990075//periciliary membrane compartment	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0019903//protein phosphatase binding;GO:0120170//intraciliary transport particle B binding	GO:0007017//microtubule-based process;GO:0007018//microtubule-based movement;GO:0007165//signal transduction;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0044782//cilium organization;GO:0046587//positive regulation of calcium-dependent cell-cell adhesion;GO:0065003//protein-containing complex assembly;GO:0072383//plus-end-directed vesicle transport along microtubule	--
ENSG00000075975	12.522	12.663	11.8	10.384	11.63	12.659	749.28	752.9	526.62	460.83	563.03	509.2	MKRN2	makorin ring finger protein 2 [Source:HGNC Symbol;Acc:HGNC:7113]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030274//LIM domain binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0043491//protein kinase B signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901485//positive regulation of transcription factor catabolic process"	--
ENSG00000076003	9.763	9.764	9.532	7.943	7.466	7.698	760	764	548	458	491	436	MCM6	minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02542;K02542	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0042555//MCM complex;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0042802//identical protein binding;GO:1990518//single-stranded 3'-5' DNA helicase activity	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:1902969//mitotic DNA replication	--
ENSG00000076043	15.153	15.266	12.699	13.109	14.109	15.33	328	343	202	216	252	249	REXO2	RNA exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:17851]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K13288	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005925//focal adhesion	GO:0000175//3'-5'-exoribonuclease activity;GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006139//nucleobase-containing compound metabolic process;GO:0006259//DNA metabolic process;GO:0009117//nucleotide metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000076053	14.752	15.03	14.569	11.343	12.528	14.972	597.01	490.72	368.04	329.24	351.52	349.37	RBM7	RNA binding motif protein 7 [Source:HGNC Symbol;Acc:HGNC:9904]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0071889//14-3-3 protein binding;GO:0097157//pre-mRNA intronic binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0016076//snRNA catabolic process;GO:0051321//meiotic cell cycle"	--
ENSG00000076067	11.007	29.208	37.454	9.75	9.547	10.451	1236.63	1164	938	882.9	1004.68	990.56	RBMS2	RNA binding motif single stranded interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9909]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	GO:0006396//RNA processing	--
ENSG00000076108	19.036	18.892	19.607	14.218	16.698	20.125	2798.37	2573	1948	1643.1	2187.32	2062.44	BAZ2A	bromodomain adjacent to zinc finger domain 2A [Source:HGNC Symbol;Acc:HGNC:962]	-	-	-	-	GO:0005634//nucleus;GO:0005677//chromatin silencing complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0033553//rDNA heterochromatin;GO:0043229//intracellular organelle;GO:0090536//NoRC complex	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0070577//lysine-acetylated histone binding	"GO:0000183//rDNA heterochromatin assembly;GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016479//negative regulation of transcription by RNA polymerase I;GO:0016575//histone deacetylation;GO:0031062//positive regulation of histone methylation;GO:0031065//positive regulation of histone deacetylation;GO:0031507//heterochromatin assembly;GO:0044030//regulation of DNA methylation"	MBD
ENSG00000076201	10.981	11.918	13.036	14.083	14.419	14.965	1190	1245	1025	1130	1305	1089	PTPN23	protein tyrosine phosphatase non-receptor type 23 [Source:HGNC Symbol;Acc:HGNC:14406]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016604//nuclear body;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding	GO:0006470//protein dephosphorylation;GO:0010633//negative regulation of epithelial cell migration;GO:0015031//protein transport;GO:0016311//dephosphorylation;GO:0030030//cell projection organization;GO:0032456//endocytic recycling;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045022//early endosome to late endosome transport;GO:0060271//cilium assembly;GO:0061357//positive regulation of Wnt protein secretion;GO:0071985//multivesicular body sorting pathway;GO:1903387//positive regulation of homophilic cell adhesion;GO:1903393//positive regulation of adherens junction organization;GO:2000643//positive regulation of early endosome to late endosome transport	--
ENSG00000076242	16.004	12.971	13.15	12.663	11.11	13.225	660	631	447	441	454	440	MLH1	mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Replication and repair;Replication and repair	ko05200//Pathways in cancer;ko05226//Gastric cancer;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko05213//Endometrial cancer;ko03460//Fanconi anemia pathway;ko03430//Mismatch repair	K08734;K08734;K08734;K08734;K08734;K08734;K08734	GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005712//chiasma;GO:0005715//late recombination nodule;GO:0016020//membrane;GO:0032300//mismatch repair complex;GO:0032389//MutLalpha complex	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0030983//mismatched DNA binding;GO:0032137//guanine/thymine mispair binding;GO:0032407//MutSalpha complex binding	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000712//resolution of meiotic recombination intermediates;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007060//male meiosis chromosome segregation;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009617//response to bacterium;GO:0016321//female meiosis chromosome segregation;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043060//meiotic metaphase I plate congression;GO:0045132//meiotic chromosome segregation;GO:0045141//meiotic telomere clustering;GO:0045143//homologous chromosome segregation;GO:0045190//isotype switching;GO:0045950//negative regulation of mitotic recombination;GO:0048298//positive regulation of isotype switching to IgA isotypes;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0048477//oogenesis;GO:0051257//meiotic spindle midzone assembly;GO:0051321//meiotic cell cycle	--
ENSG00000076248	9.891	10.475	10.182	10.366	10.454	8.71	437	463	332	339	390	280	UNG	uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572]	Human Diseases;Genetic Information Processing	Immune disease;Replication and repair	ko05340//Primary immunodeficiency;ko03410//Base excision repair	K03648;K03648	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	"GO:0003684//damaged DNA binding;GO:0004844//uracil DNA N-glycosylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0019104//DNA N-glycosylase activity;GO:0043024//ribosomal small subunit binding"	"GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043066//negative regulation of apoptotic process;GO:0045008//depyrimidination;GO:0045190//isotype switching;GO:0097510//base-excision repair, AP site formation via deaminated base removal"	--
ENSG00000076258	1.549	1.729	1.559	1.102	1.313	1.208	74	83	55	39	53	42	FMO4	flavin containing dimethylaniline monoxygenase 4 [Source:HGNC Symbol;Acc:HGNC:3772]	Metabolism;Metabolism	Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko00982//Drug metabolism - cytochrome P450;ko00430//Taurine and hypotaurine metabolism	K00485;K00485	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	GO:0042178//xenobiotic catabolic process	--
ENSG00000076321	3.7	3.962	3.69	2.841	2.507	3.746	262	282	193	149	150	193	KLHL20	kelch like family member 20 [Source:HGNC Symbol;Acc:HGNC:25056]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016605//PML body;GO:0030424//axon;GO:0030425//dendrite;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019964//interferon-gamma binding	GO:0006895//Golgi to endosome transport;GO:0007010//cytoskeleton organization;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0035455//response to interferon-alpha;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1990390//protein K33-linked ubiquitination	--
ENSG00000076344	4.295	5.296	4.8	4.033	4.828	3.529	212.84	259	176.39	148.65	202.12	127	RGS11	regulator of G protein signaling 11 [Source:HGNC Symbol;Acc:HGNC:9993]	-	-	-	-	GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0031681//G-protein beta-subunit binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000076351	18.318	18.778	19.03	20.43	19.632	25.143	2184.53	2238.64	1780.88	1664.02	1996.51	1917.07	SLC46A1	solute carrier family 46 member 1 [Source:HGNC Symbol;Acc:HGNC:30521]	Organismal Systems;Human Diseases;Organismal Systems	Digestive system;Drug resistance: antineoplastic;Digestive system	ko04978//Mineral absorption;ko01523//Antifolate resistance;ko04977//Vitamin digestion and absorption	K14613;K14613;K14613	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	GO:0005542//folic acid binding;GO:0008517//folic acid transmembrane transporter activity;GO:0015078//proton transmembrane transporter activity;GO:0015232//heme transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0140211//folic acid:proton symporter activity	GO:0006879//cellular iron ion homeostasis;GO:0015884//folic acid transport;GO:0015886//heme transport;GO:0042168//heme metabolic process;GO:0046655//folic acid metabolic process;GO:0055085//transmembrane transport;GO:0098829//intestinal folate absorption;GO:0098838//folate transmembrane transport;GO:1902600//proton transmembrane transport;GO:1904447//folate import across plasma membrane	--
ENSG00000076356	0.256	0.238	0.221	0.238	0.263	0.282	61	57	39	42	53	49	PLXNA2	plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06820	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity;GO:0042802//identical protein binding	GO:0001756//somitogenesis;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008360//regulation of cell shape;GO:0021915//neural tube development;GO:0021935//cerebellar granule cell precursor tangential migration;GO:0030334//regulation of cell migration;GO:0043087//regulation of GTPase activity;GO:0050772//positive regulation of axonogenesis;GO:0051642//centrosome localization;GO:0060037//pharyngeal system development;GO:0060174//limb bud formation;GO:0071526//semaphorin-plexin signaling pathway;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000076382	1.495	1.128	1.221	0.928	0.83	1.235	90	89	67	54	50	37	SPAG5	sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016604//nuclear body;GO:0030496//midbody;GO:0034451//centriolar satellite;GO:0035371//microtubule plus-end;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole"	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007059//chromosome segregation;GO:0032388//positive regulation of intracellular transport;GO:0051301//cell division;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0071539//protein localization to centrosome;GO:0090235//regulation of metaphase plate congression;GO:1905832//positive regulation of spindle assembly	--
ENSG00000076513	13.581	13.757	10.073	8.214	9.803	11.688	908	829	527	443	607	548	ANKRD13A	ankyrin repeat domain 13A [Source:HGNC Symbol;Acc:HGNC:21268]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0140036//ubiquitin-dependent protein binding	GO:0002091//negative regulation of receptor internalization;GO:1905667//negative regulation of protein localization to endosome	--
ENSG00000076554	29.127	25.293	22.045	19.328	19.894	22.628	1620.88	1373.23	910	787.62	982.55	925	TPD52	tumor protein D52 [Source:HGNC Symbol;Acc:HGNC:12005]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0009653//anatomical structure morphogenesis;GO:0030183//B cell differentiation;GO:0046903//secretion	--
ENSG00000076555	5.166	5.299	6.075	6.162	4.264	6.215	649	668	614	554	552	547	ACACB	acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04920//Adipocytokine signaling pathway;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism;ko00061//Fatty acid biosynthesis	K01946;K01946;K01946;K01946;K01946;K01946;K01946;K01946;K01946;K01946	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003989//acetyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006084//acetyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0008152//metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010629//negative regulation of gene expression;GO:0010884//positive regulation of lipid storage;GO:0010906//regulation of glucose metabolic process;GO:0014070//response to organic cyclic compound;GO:0031667//response to nutrient levels;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0043086//negative regulation of catalytic activity;GO:0044281//small molecule metabolic process;GO:0046322//negative regulation of fatty acid oxidation;GO:0050995//negative regulation of lipid catabolic process;GO:0051289//protein homotetramerization;GO:0060421//positive regulation of heart growth;GO:0097009//energy homeostasis;GO:2001295//malonyl-CoA biosynthetic process	--
ENSG00000076604	11.884	18.694	17.05	25.731	18.852	19.624	638	799	600	763	791	662	TRAF4	TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Cancer: specific types	ko05200//Pathways in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer	K09848;K09848;K09848	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm	GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050699//WW domain binding	GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0030323//respiratory tube development;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade	--
ENSG00000076641	4.994	4.406	4.247	3.919	3.851	4.533	1113	987	699	647	725	735	PAG1	phosphoprotein membrane anchor with glycosphingolipid microdomains 1 [Source:HGNC Symbol;Acc:HGNC:30043]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0050863//regulation of T cell activation;GO:0050868//negative regulation of T cell activation	--
ENSG00000076650	2.81	2.57	2.046	1.509	1.52	2.18	186	171	100	74	85	105	GPATCH1	G-patch domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24658]	-	-	-	-	GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing"	--
ENSG00000076662	1.98	2.41	2.554	2.187	1.5	1.495	55	59	46	49	33	30	ICAM3	intercellular adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:5346]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06486	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding	GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000076685	33.854	30.754	38.668	32.993	32.957	42.076	2094.85	2016.08	1741.75	1493.61	1739	1857.16	NT5C2	"5'-nucleotidase, cytosolic II [Source:HGNC Symbol;Acc:HGNC:8022]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050146//nucleoside phosphotransferase activity;GO:0050483//IMP 5'-nucleotidase activity;GO:0050484//GMP 5'-nucleotidase activity	GO:0000255//allantoin metabolic process;GO:0006204//IMP catabolic process;GO:0008152//metabolic process;GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0046037//GMP metabolic process;GO:0046040//IMP metabolic process;GO:0046054//dGMP metabolic process;GO:0046085//adenosine metabolic process;GO:0046939//nucleotide phosphorylation	--
ENSG00000076706	6.521	7.973	5.945	6.651	7.581	7.289	450	553	303	340	442	366	MCAM	melanoma cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:6934]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0001525//angiogenesis;GO:0003094//glomerular filtration;GO:0007155//cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0030335//positive regulation of cell migration;GO:0061042//vascular wound healing	--
ENSG00000076716	1.828	2.263	0.935	1.627	1.749	0.949	188	234	71	124	152	71	GPC4	glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K08110	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0045202//synapse;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	"GO:0005515//protein binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	"GO:0009966//regulation of signal transduction;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0099560//synaptic membrane adhesion;GO:1905475//regulation of protein localization to membrane;GO:1905606//regulation of presynapse assembly"	--
ENSG00000076770	1.063	1.109	1.192	0.979	0.641	0.903	179	114	99	80	88	89	MBNL3	muscleblind like splicing regulator 3 [Source:HGNC Symbol;Acc:HGNC:20564]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0045662//negative regulation of myoblast differentiation"	--
ENSG00000076826	10.888	12.564	13.417	11.403	12.522	11.493	937	1085	852	726	909	718	CAMSAP3	calmodulin regulated spectrin associated protein family member 3 [Source:HGNC Symbol;Acc:HGNC:29307]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036449//microtubule minus-end;GO:0042995//cell projection	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0030507//spectrin binding;GO:0051011//microtubule minus-end binding;GO:0051015//actin filament binding	GO:0000226//microtubule cytoskeleton organization;GO:0001701//in utero embryonic development;GO:0003341//cilium movement;GO:0007026//negative regulation of microtubule depolymerization;GO:0009792//embryo development ending in birth or egg hatching;GO:0030030//cell projection organization;GO:0030334//regulation of cell migration;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0031113//regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development;GO:0033043//regulation of organelle organization;GO:0034453//microtubule anchoring;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045218//zonula adherens maintenance;GO:0051893//regulation of focal adhesion assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0090136//epithelial cell-cell adhesion;GO:0098840//protein transport along microtubule;GO:1903358//regulation of Golgi organization	--
ENSG00000076864	4.427	4.085	3.445	3.998	5.156	3.298	281	258	176	204	267	156	RAP1GAP	RAP1 GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:9858]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17700	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity	GO:0002250//adaptive immune response;GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0045665//negative regulation of neuron differentiation;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity;GO:1903697//negative regulation of microvillus assembly;GO:1904425//negative regulation of GTP binding;GO:1904442//negative regulation of thyroid gland epithelial cell proliferation;GO:1990792//cellular response to glial cell derived neurotrophic factor	--
ENSG00000076924	22.567	24.046	22.17	27.908	26.236	20.927	1239	1327	899	1135	1217	836	XAB2	XPA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14089]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12867	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071014//post-mRNA release spliceosomal complex	GO:0005515//protein binding	"GO:0000349//generation of catalytic spliceosome for first transesterification step;GO:0000398//mRNA splicing, via spliceosome;GO:0001824//blastocyst development;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0021987//cerebral cortex development"	--
ENSG00000076928	8.538	9.104	11.383	9.96	11.836	10.453	573	611	537	495	666	511	ARHGEF1	Rho guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:681]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Circulatory system;Immune system;Endocrine system	"ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04928//Parathyroid hormone synthesis, secretion and action"	K12330;K12330;K12330;K12330;K12330;K12330;K12330;K12330;K12330;K12330	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0001664//G protein-coupled receptor binding;GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000076944	23.832	24.966	23.89	26.791	26.752	22.314	931	950	674	773	877	625	STXBP2	syntaxin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:11445]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0044194//cytolytic granule;GO:0070062//extracellular exosome;GO:0070820//tertiary granule;GO:0098793//presynapse	GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0030348//syntaxin-3 binding	GO:0001909//leukocyte mediated cytotoxicity;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007269//neurotransmitter secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0043304//regulation of mast cell degranulation;GO:0043312//neutrophil degranulation	--
ENSG00000076984	7.339	7.696	8.639	8.408	9.136	7.31	514	542	447	437	541	373	MAP2K7	mitogen-activated protein kinase kinase 7 [Source:HGNC Symbol;Acc:HGNC:6847]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Cellular community - eukaryotes;Folding, sorting and degradation;Infectious disease: viral;Endocrine and metabolic disease;Cardiovascular disease;Immune system;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Immune system;Immune system;Endocrine system;Signal transduction"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05132//Salmonella infection;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04530//Tight junction;ko04141//Protein processing in endoplasmic reticulum;ko05161//Hepatitis B;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04668//TNF signaling pathway;ko04660//T cell receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04912//GnRH signaling pathway;ko04012//ErbB signaling pathway	K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431;K04431	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008545//JUN kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006970//response to osmotic stress;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0009408//response to heat;GO:0009411//response to UV;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0034612//response to tumor necrosis factor;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043507//positive regulation of JUN kinase activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0051403//stress-activated MAPK cascade;GO:0051973//positive regulation of telomerase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072709//cellular response to sorbitol;GO:0090398//cellular senescence;GO:1904355//positive regulation of telomere capping"	--
ENSG00000077009	12.018	14.384	10.185	13.691	15.067	11.246	288	342	180	244	303	193	NMRK2	nicotinamide riboside kinase 2 [Source:HGNC Symbol;Acc:HGNC:17871]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K10524;K10524	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0050262//ribosylnicotinamide kinase activity;GO:0061769//ribosylnicotinate kinase activity	GO:0009435//NAD biosynthetic process;GO:0016310//phosphorylation;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019674//NAD metabolic process;GO:0045662//negative regulation of myoblast differentiation	--
ENSG00000077044	3.638	4.136	3.715	4.584	4.734	4.034	476	544	359	426	441	384	DGKD	diacylglycerol kinase delta [Source:HGNC Symbol;Acc:HGNC:2851]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0019992//diacylglycerol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0010033//response to organic substance;GO:0015031//protein transport;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0090038//negative regulation of protein kinase C signaling;GO:2000370//positive regulation of clathrin-dependent endocytosis	--
ENSG00000077063	3.832	3.974	4.712	3.435	3.01	4.64	461	393	256	273	308	351	CTTNBP2	cortactin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15679]	-	-	-	-	GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098871//postsynaptic actin cytoskeleton;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0007420//brain development;GO:0050807//regulation of synapse organization;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton	--
ENSG00000077080	0	0	0	0	0	0	0	0	0	0	0	0	ACTL6B	actin like 6B [Source:HGNC Symbol;Acc:HGNC:160]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11652;K11652	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0035060//brahma complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex;GO:0140288//GBAF complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005200//structural constituent of cytoskeleton	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0016358//dendrite development;GO:0021510//spinal cord development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0042551//neuron maturation;GO:0043967//histone H4 acetylation;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000077092	8.634	8.631	7.889	9.305	8.579	8.24	551	552	353	437	461	391	RARB	retinoic acid receptor beta [Source:HGNC Symbol;Acc:HGNC:9865]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05226//Gastric cancer;ko05222//Small cell lung cancer;ko05223//Non-small cell lung cancer	K08528;K08528;K08528;K08528	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0002068//glandular epithelial cell development;GO:0003417//growth plate cartilage development;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0009755//hormone-mediated signaling pathway;GO:0021756//striatum development;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0035116//embryonic hindlimb morphogenesis;GO:0035264//multicellular organism growth;GO:0043065//positive regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048048//embryonic eye morphogenesis;GO:0048384//retinoic acid receptor signaling pathway;GO:0048566//embryonic digestive tract development;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060348//bone development;GO:0061037//negative regulation of cartilage development"	THR-like
ENSG00000077097	31.593	22.812	19.339	15.286	16.884	17.011	3358	2408	1553	1188	1588	1310	TOP2B	DNA topoisomerase II beta [Source:HGNC Symbol;Acc:HGNC:11990]	Human Diseases	Drug resistance: antineoplastic	ko01524//Platinum drug resistance	K03164	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:1990904//ribonucleoprotein complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003916//DNA topoisomerase activity;GO:0003918//DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0005080//protein kinase C binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016853//isomerase activity;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	GO:0000712//resolution of meiotic recombination intermediates;GO:0000819//sister chromatid segregation;GO:0001764//neuron migration;GO:0006259//DNA metabolic process;GO:0006265//DNA topological change;GO:0007409//axonogenesis;GO:0030900//forebrain development;GO:0045870//positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	--
ENSG00000077147	68.345	58.708	59.835	55.123	51.575	63.124	6342	5291	4011	3475	3963	4145	TM9SF3	transmembrane 9 superfamily member 3 [Source:HGNC Symbol;Acc:HGNC:21529]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0072657//protein localization to membrane	--
ENSG00000077150	5.328	5.866	5.76	7.138	6.366	6.338	338	369	267	332	341	295	NFKB2	nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Development and regeneration;Immune system;Infectious disease: bacterial	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04064//NF-kappa B signaling pathway;ko05224//Breast cancer;ko04380//Osteoclast differentiation;ko04625//C-type lectin receptor signaling pathway;ko05134//Legionellosis	K04469;K04469;K04469;K04469;K04469;K04469;K04469;K04469;K04469;K04469	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0033257//Bcl3/NF-kappaB2 complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002268//follicular dendritic cell differentiation;GO:0002467//germinal center formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0030198//extracellular matrix organization;GO:0038061//NIK/NF-kappaB signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048536//spleen development"	RHD
ENSG00000077152	2.973	2.513	2.082	2.32	2.34	1.811	54	46	28	31	36	24	UBE2T	ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K13960	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0035519//protein K29-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination	--
ENSG00000077157	8.888	8.893	9.563	8.43	12.233	10.234	1689	1745	1282.99	1217.99	1614.99	1145	PPP1R12B	protein phosphatase 1 regulatory subunit 12B [Source:HGNC Symbol;Acc:HGNC:7619]	Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Cell motility;Cancer: overview;Cellular community - eukaryotes;Endocrine system;Circulatory system	ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction	K12329;K12329;K12329;K12329;K12329	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030018//Z disc;GO:0031672//A band	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0019208//phosphatase regulator activity;GO:0019901//protein kinase binding	GO:0006937//regulation of muscle contraction;GO:0007165//signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity	--
ENSG00000077232	16.237	14.214	13.541	10.769	11.279	12.875	3064	2520	1734	1461	1769	1748	DNAJC10	DnaJ heat shock protein family (Hsp40) member C10 [Source:HGNC Symbol;Acc:HGNC:24637]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09530	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034663//endoplasmic reticulum chaperone complex	"GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0015036//disulfide oxidoreductase activity;GO:0016491//oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0030544//Hsp70 protein binding;GO:0051087//chaperone binding;GO:0051117//ATPase binding;GO:0051787//misfolded protein binding"	GO:0001933//negative regulation of protein phosphorylation;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032781//positive regulation of ATPase activity;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	--
ENSG00000077235	33.457	34.258	36.136	30.931	32.676	34.526	4907	5048	3889	3364	4046	3664	GTF3C1	general transcription factor IIIC subunit 1 [Source:HGNC Symbol;Acc:HGNC:4664]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:1990904//ribonucleoprotein complex	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0009303//rRNA transcription;GO:0009304//tRNA transcription;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III	--
ENSG00000077238	3.341	3.044	2.693	3.122	2.9	3.968	228	193	133	135	168	147	IL4R	interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K05071;K05071;K05071;K05071;K05071;K05071;K05071;K05071	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004913//interleukin-4 receptor activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0002639//positive regulation of immunoglobulin production;GO:0006955//immune response;GO:0007165//signal transduction;GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0030728//ovulation;GO:0032722//positive regulation of chemokine production;GO:0035771//interleukin-4-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042832//defense response to protozoan;GO:0043032//positive regulation of macrophage activation;GO:0043306//positive regulation of mast cell degranulation;GO:0043627//response to estrogen;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901741//positive regulation of myoblast fusion;GO:1990834//response to odorant	--
ENSG00000077254	36.542	29.277	30.067	25.502	27.252	31.642	2907	2366	1757	1500	1818	1831	USP33	ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030891//VCB complex;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm	GO:0001664//G protein-coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006897//endocytosis;GO:0007411//axon guidance;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0016477//cell migration;GO:0016579//protein deubiquitination;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0050821//protein stabilization;GO:0051298//centrosome duplication;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000077264	0.3	0.332	0.228	0.103	0.091	0.211	25	32	12	10	7	11	PAK3	p21 (RAC1) activated kinase 3 [Source:HGNC Symbol;Acc:HGNC:8592]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cell motility;Infectious disease: viral;Cellular community - eukaryotes;Development and regeneration;Immune system;Signal transduction;Cancer: specific types	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04510//Focal adhesion;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma	K05733;K05733;K05733;K05733;K05733;K05733;K05733;K05733;K05733;K05733	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0051020//GTPase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007409//axonogenesis;GO:0008152//metabolic process;GO:0010763//positive regulation of fibroblast migration;GO:0010975//regulation of neuron projection development;GO:0016310//phosphorylation;GO:0016358//dendrite development;GO:0030833//regulation of actin filament polymerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0043525//positive regulation of neuron apoptotic process;GO:0048013//ephrin receptor signaling pathway;GO:0050770//regulation of axonogenesis;GO:0050808//synapse organization;GO:0060996//dendritic spine development;GO:0060997//dendritic spine morphogenesis;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071407//cellular response to organic cyclic compound;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000077274	9.964	8.447	8.058	12.457	14.218	15.252	730	622	436	676	880	813	CAPN6	calpain 6 [Source:HGNC Symbol;Acc:HGNC:1483]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0048471//perinuclear region of cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0001578//microtubule bundle formation;GO:0006508//proteolysis;GO:0051493//regulation of cytoskeleton organization	--
ENSG00000077279	0.064	0.071	0.139	0.028	0.028	0	11	13	4	2	3	0	DCX	doublecortin [Source:HGNC Symbol;Acc:HGNC:2714]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005930//axoneme;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding	GO:0001764//neuron migration;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0021766//hippocampus development;GO:0021819//layer formation in cerebral cortex;GO:0021860//pyramidal neuron development;GO:0021952//central nervous system projection neuron axonogenesis;GO:0030154//cell differentiation;GO:0035082//axoneme assembly;GO:0035556//intracellular signal transduction;GO:0042461//photoreceptor cell development;GO:0048675//axon extension;GO:0048813//dendrite morphogenesis;GO:0060041//retina development in camera-type eye	--
ENSG00000077312	27.003	24.486	27.203	26.925	27.672	26.2	647	593	473	505	590	491	SNRPA	small nuclear ribonucleoprotein polypeptide A [Source:HGNC Symbol;Acc:HGNC:11151]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11091	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005685//U1 snRNP	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030619//U1 snRNA binding;GO:0042802//identical protein binding;GO:1990446//U1 snRNP binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:1900363//regulation of mRNA polyadenylation"	--
ENSG00000077327	0.352	0.407	0.74	0.305	0.602	0.167	18	21	23	12	12	6	SPAG6	sperm associated antigen 6 [Source:HGNC Symbol;Acc:HGNC:11215]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007288//sperm axoneme assembly;GO:0030030//cell projection organization;GO:0046847//filopodium assembly;GO:1990138//neuron projection extension	--
ENSG00000077348	5.065	5.143	4.448	5.396	5.775	5.511	103	107	68	81	101	83	EXOSC5	exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12590	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0101019//nucleolar exosome (RNase complex);GO:1902494//catalytic complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034475//U4 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045006//DNA deamination;GO:0051252//regulation of RNA metabolic process;GO:0051607//defense response to virus;GO:0071028//nuclear mRNA surveillance;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000077380	32.943	34.093	29.881	28.57	26.634	25.138	1737	1761	1162	997	1231	867	DYNC1I2	dynein cytoplasmic 1 intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2964]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10415;K10415;K10415	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0031982//vesicle	GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0007018//microtubule-based movement;GO:0010970//transport along microtubule	--
ENSG00000077420	0.037	0.073	0	0.025	0.108	0	2	4	0	1	5	0	APBB1IP	amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04015//Rap1 signaling pathway;ko04611//Platelet activation	K17704;K17704	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042101//T cell receptor complex;GO:0042995//cell projection	GO:0005515//protein binding	GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0007165//signal transduction;GO:0045785//positive regulation of cell adhesion	--
ENSG00000077454	6.343	7.081	8.054	8.85	9.179	9.198	418	469	392	432	511	441	LRCH4	leucine rich repeats and calponin homology domain containing 4 [Source:HGNC Symbol;Acc:HGNC:6691]	-	-	-	-	GO:0016605//PML body	GO:0005515//protein binding	GO:0007399//nervous system development	--
ENSG00000077458	4.723	2.216	3.781	3.726	2.478	2.541	261	165	156	127	121	146	FAM76B	family with sequence similarity 76 member B [Source:HGNC Symbol;Acc:HGNC:28492]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0005515//protein binding	-	--
ENSG00000077463	6.257	6.709	8.108	8.668	8.086	9.893	198	215	188	207	215	229	SIRT6	sirtuin 6 [Source:HGNC Symbol;Acc:HGNC:14934]	Metabolism;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Environmental adaptation;Cancer: overview;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko05230//Central carbon metabolism in cancer;ko00760//Nicotinate and nicotinamide metabolism	K11416;K11416;K11416;K11416	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0099115//chromosome, subtelomeric region"	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019213//deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0046872//metal ion binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0070403//NAD+ binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006284//base-excision repair;GO:0006471//protein ADP-ribosylation;GO:0006476//protein deacetylation;GO:0008285//negative regulation of cell population proliferation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0031509//subtelomeric heterochromatin assembly;GO:0031648//protein destabilization;GO:0032206//positive regulation of telomere maintenance;GO:0042593//glucose homeostasis;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045820//negative regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046325//negative regulation of glucose import;GO:0048146//positive regulation of fibroblast proliferation;GO:0061647//histone H3-K9 modification;GO:0070932//histone H3 deacetylation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901485//positive regulation of transcription factor catabolic process;GO:1902732//positive regulation of chondrocyte proliferation;GO:1905555//positive regulation of blood vessel branching;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1990619//histone H3-K9 deacetylation;GO:2000648//positive regulation of stem cell proliferation"	--
ENSG00000077498	393.033	405.817	416.894	454.783	413.512	468.965	16810	17446	13169	14408	14942	14594	TYR	tyrosinase [Source:HGNC Symbol;Acc:HGNC:12442]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Amino acid metabolism	ko01100//Metabolic pathways;ko04916//Melanogenesis;ko00350//Tyrosine metabolism	K00505;K00505;K00505	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0004497//monooxygenase activity;GO:0004503//tyrosinase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006583//melanin biosynthetic process from tyrosine;GO:0006726//eye pigment biosynthetic process;GO:0007601//visual perception;GO:0008283//cell population proliferation;GO:0009411//response to UV;GO:0009637//response to blue light;GO:0033280//response to vitamin D;GO:0042438//melanin biosynthetic process;GO:0043473//pigmentation;GO:0048538//thymus development;GO:0051591//response to cAMP	--
ENSG00000077514	4.284	3.461	3.958	2.349	2.379	3.231	295	255	221	121	151	166	POLD3	"DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K03504;K03504;K03504;K03504;K03504	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016035//zeta DNA polymerase complex;GO:0031981//nuclear lumen;GO:0043625//delta DNA polymerase complex	GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	"GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006281//DNA repair;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0042276//error-prone translesion synthesis;GO:0071897//DNA biosynthetic process;GO:1904161//DNA synthesis involved in UV-damage excision repair"	--
ENSG00000077522	0.124	0.096	0.073	0.096	0.062	0.033	6	8	4	4	5	1	ACTN2	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K21073	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030864//cortical actin cytoskeleton;GO:0031093//platelet alpha granule lumen;GO:0031143//pseudopodium;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	"GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle;GO:0019904//protein domain specific binding;GO:0030274//LIM domain binding;GO:0030374//nuclear receptor coactivator activity;GO:0031432//titin binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0051373//FATZ binding;GO:0070080//titin Z domain binding"	"GO:0006936//muscle contraction;GO:0007155//cell adhesion;GO:0030035//microspike assembly;GO:0030036//actin cytoskeleton organization;GO:0042391//regulation of membrane potential;GO:0042981//regulation of apoptotic process;GO:0043267//negative regulation of potassium ion transport;GO:0043268//positive regulation of potassium ion transport;GO:0045214//sarcomere organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048041//focal adhesion assembly;GO:0051695//actin filament uncapping;GO:0055001//muscle cell development;GO:0055013//cardiac muscle cell development;GO:0072659//protein localization to plasma membrane;GO:0086097//phospholipase C-activating angiotensin-activated signaling pathway;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:2000009//negative regulation of protein localization to cell surface;GO:2001137//positive regulation of endocytic recycling;GO:2001259//positive regulation of cation channel activity"	--
ENSG00000077549	75.661	79.531	78.327	75.936	82.116	64.449	2674	2808	2033	1989	2454	1649	CAPZB	capping actin protein of muscle Z-line subunit beta [Source:HGNC Symbol;Acc:HGNC:1491]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K10365	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005903//brush border;GO:0008290//F-actin capping protein complex;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030027//lamellipodium;GO:0030863//cortical cytoskeleton;GO:0032279//asymmetric synapse;GO:0070062//extracellular exosome;GO:0071203//WASH complex;GO:0097224//sperm connecting piece;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0000902//cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0008154//actin polymerization or depolymerization;GO:0010591//regulation of lamellipodium assembly;GO:0022604//regulation of cell morphogenesis;GO:0030030//cell projection organization;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0051016//barbed-end actin filament capping;GO:0051490//negative regulation of filopodium assembly;GO:0051693//actin filament capping	--
ENSG00000077585	35.111	34.12	36.146	37.823	34.867	34.18	1437	1412	1062	1121	1203	998	GPR137B	G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0043030//regulation of macrophage activation;GO:0043087//regulation of GTPase activity;GO:0045671//negative regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:0150032//positive regulation of protein localization to lysosome;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000077616	3.336	4.963	3.611	3.724	3.341	3.244	230	241	151	146	128	158	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:14526]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008237//metallopeptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008152//metabolic process	--
ENSG00000077684	8.512	9.691	6.551	6.019	7.081	5.807	870	846	493	442	522.92	447	JADE1	jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0016570//histone modification;GO:0030308//negative regulation of cell growth;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000278//regulation of DNA biosynthetic process"	--
ENSG00000077713	3.115	2.315	3.046	2.752	3.323	2.828	162	121	117	106	146	107	SLC25A43	solute carrier family 25 member 43 [Source:HGNC Symbol;Acc:HGNC:30557]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0055085//transmembrane transport	--
ENSG00000077721	36.002	35.34	32.38	34.862	30.786	33.791	1261	1243	854	901	910	835	UBE2A	ubiquitin conjugating enzyme E2 A [Source:HGNC Symbol;Acc:HGNC:12472]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10573	GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0033503//HULC complex	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell population proliferation;GO:0009411//response to UV;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0033522//histone H2A ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000077782	65.773	66.828	64.716	62.804	62.797	65.565	4938	5154	3859	3793	4470	3826	FGFR1	fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Environmental adaptation;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: overview;Cellular community - eukaryotes	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko05224//Breast cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko05218//Melanoma;ko05230//Central carbon metabolism in cancer;ko04520//Adherens junction"	K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362;K04362	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0090722//receptor-receptor interaction	GO:0000165//MAPK cascade;GO:0001501//skeletal system development;GO:0001764//neuron migration;GO:0001837//epithelial to mesenchymal transition;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010518//positive regulation of phospholipase activity;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0043009//chordate embryonic development;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045595//regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0046777//protein autophosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048513//animal organ development;GO:0048705//skeletal system morphogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0071363//cellular response to growth factor stimulus;GO:0071495//cellular response to endogenous stimulus;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000077800	0	0	0	0	0	0	0	0	0	0	0	0	FKBP6	FKBP prolyl isomerase family member 6 (inactive) [Source:HGNC Symbol;Acc:HGNC:3722]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0051879//Hsp90 protein binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0045070//positive regulation of viral genome replication;GO:0051321//meiotic cell cycle	--
ENSG00000077935	0.013	0.04	0	0	0	0	1	3	0	0	0	0	SMC1B	structural maintenance of chromosomes 1B [Source:HGNC Symbol;Acc:HGNC:11112]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04114//Oocyte meiosis;ko04110//Cell cycle	K06636;K06636	"GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0008278//cohesin complex;GO:0030893//meiotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007049//cell cycle;GO:0007062//sister chromatid cohesion;GO:0051276//chromosome organization;GO:0051321//meiotic cell cycle	--
ENSG00000077942	49.133	54.634	49.233	48.229	49.252	41.39	2129	2449	1468	1490	1816	1338	FBLN1	fibulin 1 [Source:HGNC Symbol;Acc:HGNC:3600]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071953//elastic fiber	GO:0001968//fibronectin binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016504//peptidase activator activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0070051//fibrinogen binding	"GO:0001933//negative regulation of protein phosphorylation;GO:0007162//negative regulation of cell adhesion;GO:0007566//embryo implantation;GO:0010628//positive regulation of gene expression;GO:0010952//positive regulation of peptidase activity;GO:0030198//extracellular matrix organization;GO:0048146//positive regulation of fibroblast proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071635//negative regulation of transforming growth factor beta production;GO:0072378//blood coagulation, fibrin clot formation;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1904188//negative regulation of transformation of host cell by virus;GO:1904237//positive regulation of substrate-dependent cell migration, cell attachment to substrate;GO:2000146//negative regulation of cell motility;GO:2000647//negative regulation of stem cell proliferation"	--
ENSG00000077943	0.022	0.022	0.03	0	0.026	0	3	3	3	0	3	0	ITGA8	integrin subunit alpha 8 [Source:HGNC Symbol;Acc:HGNC:6144]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06584;K06584;K06584;K06584;K06584;K06584;K06584;K06584;K06584	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032591//dendritic spine membrane;GO:0034678//integrin alpha8-beta1 complex;GO:0043204//perikaryon;GO:0045177//apical part of cell	GO:0005178//integrin binding;GO:0046872//metal ion binding	GO:0001656//metanephros development;GO:0001822//kidney development;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007613//memory;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033627//cell adhesion mediated by integrin;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042472//inner ear morphogenesis;GO:0045184//establishment of protein localization;GO:0048333//mesodermal cell differentiation;GO:0048745//smooth muscle tissue development;GO:0098609//cell-cell adhesion;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	--
ENSG00000077984	0	0	0	0	0	0	0	0	0	0	0	0	CST7	cystatin F [Source:HGNC Symbol;Acc:HGNC:2479]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle	GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0042803//protein homodimerization activity	GO:0006955//immune response;GO:0010466//negative regulation of peptidase activity;GO:0031643//positive regulation of myelination;GO:0097340//inhibition of cysteine-type endopeptidase activity;GO:1903979//negative regulation of microglial cell activation	--
ENSG00000078018	0.835	0.765	0.346	0.604	0.484	0.556	75	61	30	38	36	31	MAP2	microtubule associated protein 2 [Source:HGNC Symbol;Acc:HGNC:6839]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0030425//dendrite;GO:0032839//dendrite cytoplasm;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043198//dendritic shaft;GO:0043203//axon hillock;GO:0044294//dendritic growth cone;GO:0044307//dendritic branch;GO:0097441//basal dendrite;GO:0110165//cellular anatomical entity;GO:0150001//primary dendrite;GO:0150002//distal dendrite;GO:0150014//apical distal dendrite;GO:1902737//dendritic filopodium;GO:1990635//proximal dendrite;GO:1990769//proximal neuron projection	GO:0002162//dystroglycan binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0048156//tau protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0016358//dendrite development;GO:0021954//central nervous system neuron development;GO:0030517//negative regulation of axon extension;GO:0031113//regulation of microtubule polymerization;GO:0031115//negative regulation of microtubule polymerization;GO:0031175//neuron projection development;GO:0032880//regulation of protein localization;GO:0048813//dendrite morphogenesis;GO:1901953//positive regulation of anterograde dense core granule transport;GO:1902513//regulation of organelle transport along microtubule;GO:1903744//positive regulation of anterograde synaptic vesicle transport;GO:1904527//negative regulation of microtubule binding	--
ENSG00000078043	11.493	11.263	11.16	7.769	10.614	10.153	791	706	510	357	564	480	PIAS2	protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311]	Environmental Information Processing;Genetic Information Processing	"Signal transduction;Folding, sorting and degradation"	ko04630//JAK-STAT signaling pathway;ko04120//Ubiquitin mediated proteolysis	K16063;K16063	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061665//SUMO ligase activity	"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016925//protein sumoylation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0060255//regulation of macromolecule metabolic process;GO:0060766//negative regulation of androgen receptor signaling pathway"	zf-MIZ
ENSG00000078053	1.016	0.756	0.575	1.003	0.624	1	58	45	24	45	33	41	AMPH	amphiphysin [Source:HGNC Symbol;Acc:HGNC:471]	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04144//Endocytosis;ko04666//Fc gamma R-mediated phagocytosis	K12562;K12562	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031256//leading edge membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0006897//endocytosis;GO:0007268//chemical synaptic transmission;GO:0048488//synaptic vesicle endocytosis	--
ENSG00000078061	31.208	30.173	33.219	36.858	36.944	31.616	1515	1485	1200	1330	1514	1099	ARAF	"A-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:646]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: overview;Cell motility;Cancer: overview;Substance dependence;Immune system;Cancer: specific types;Infectious disease: viral;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Circulatory system;Nervous system;Endocrine system;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Nervous system;Cancer: specific types;Nervous system;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer"	K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845;K08845	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0032006//regulation of TOR signaling;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000078070	7.457	5.752	6.302	6.421	6.936	6.977	380	289	228	241	287	254	MCCC1	methylcrotonyl-CoA carboxylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:6936]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K01968;K01968	"GO:0002169//3-methylcrotonyl-CoA carboxylase complex, mitochondrial;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1905202//methylcrotonoyl-CoA carboxylase complex"	GO:0000166//nucleotide binding;GO:0004075//biotin carboxylase activity;GO:0004485//methylcrotonoyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006552//leucine catabolic process;GO:0006768//biotin metabolic process;GO:0006790//sulfur compound metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0043603//cellular amide metabolic process;GO:0044281//small molecule metabolic process	--
ENSG00000078081	0	0.22	0.045	0	0.11	0.051	0	10	1	0	5	2	LAMP3	lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K06562	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0097233//alveolar lamellar body membrane	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0035455//response to interferon-alpha;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072594//establishment of protein localization to organelle;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:1903900//regulation of viral life cycle	--
ENSG00000078098	4.059	4.335	1.462	1.593	1.727	1.894	227	243	60	66	81	46	FAP	fibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031258//lamellipodium membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0045178//basal part of cell;GO:0110165//cellular anatomical entity;GO:1905368//peptidase complex	GO:0002020//protease binding;GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0001525//angiogenesis;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0010710//regulation of collagen catabolic process;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0043542//endothelial cell migration;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0051726//regulation of cell cycle;GO:0051917//regulation of fibrinolysis;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0097325//melanocyte proliferation;GO:1900119//positive regulation of execution phase of apoptosis;GO:1902362//melanocyte apoptotic process;GO:1903054//negative regulation of extracellular matrix organization	--
ENSG00000078114	2.125	2.516	2.416	3.003	3.495	2.61	237	243	180	234	311	207	NEBL	nebulette [Source:HGNC Symbol;Acc:HGNC:16932]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0031674//I band;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle;GO:0031005//filamin binding;GO:0051015//actin filament binding	GO:0071691//cardiac muscle thin filament assembly	--
ENSG00000078124	6.431	6.12	7.439	5.701	6.117	6.613	710	536	440	327	446	361	ACER3	alkaline ceramidase 3 [Source:HGNC Symbol;Acc:HGNC:16066]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K04711;K04711	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0046872//metal ion binding;GO:0070774//phytoceramidase activity;GO:0071633//dihydroceramidase activity;GO:0102121//ceramidase activity"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006954//inflammatory response;GO:0008284//positive regulation of cell population proliferation;GO:0030148//sphingolipid biosynthetic process;GO:0042552//myelination;GO:0043067//regulation of programmed cell death;GO:0046512//sphingosine biosynthetic process;GO:0046514//ceramide catabolic process;GO:0071602//phytosphingosine biosynthetic process	--
ENSG00000078140	21.604	16.535	18.224	19.92	14.888	20.567	1773	1339	1239	1078	1151	1272	UBE2K	ubiquitin conjugating enzyme E2 K [Source:HGNC Symbol;Acc:HGNC:4914]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K04649	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032433//filopodium tip	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035458//cellular response to interferon-beta;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway	--
ENSG00000078142	19.42	14.114	15.43	11.892	18.336	15.864	1194	1097	805	637	809	701	PIK3C3	phosphatidylinositol 3-kinase catalytic subunit type 3 [Source:HGNC Symbol;Acc:HGNC:8974]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Metabolism;Cellular Processes	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Transport and catabolism;Neurodegenerative disease;Signal transduction;Signal transduction;Carbohydrate metabolism;Transport and catabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism;ko04136//Autophagy - other	K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914;K00914	"GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0005930//axoneme;GO:0016020//membrane;GO:0030496//midbody;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034271//phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272//phosphatidylinositol 3-kinase complex, class III, type II;GO:0035032//phosphatidylinositol 3-kinase complex, class III;GO:0044754//autolysosome;GO:0045335//phagocytic vesicle"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity	GO:0000045//autophagosome assembly;GO:0006468//protein phosphorylation;GO:0006497//protein lipidation;GO:0006622//protein targeting to lysosome;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0007032//endosome organization;GO:0007049//cell cycle;GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0016236//macroautophagy;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016485//protein processing;GO:0030242//autophagy of peroxisome;GO:0032465//regulation of cytokinesis;GO:0034497//protein localization to phagophore assembly site;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0042149//cellular response to glucose starvation;GO:0043201//response to leucine;GO:0044238//primary metabolic process;GO:0045022//early endosome to late endosome transport;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050708//regulation of protein secretion;GO:0051301//cell division;GO:0097352//autophagosome maturation	--
ENSG00000078177	2.03	0.646	0.888	0.534	0.912	0.685	317	131	110	73	106	95	N4BP2	NEDD4 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29851]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0043130//ubiquitin binding;GO:0046404//polydeoxyribonucleotide 5'-hydroxyl-kinase activity	GO:0016310//phosphorylation;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000078237	2.187	1.476	1.909	1.251	1.604	1.413	322.38	243.96	226.22	138.63	212.2	175.02	TIGAR	TP53 induced glycolysis regulatory phosphatase [Source:HGNC Symbol;Acc:HGNC:1185]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05230//Central carbon metabolism in cancer;ko00051//Fructose and mannose metabolism	K14634;K14634;K14634	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004083//bisphosphoglycerate 2-phosphatase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity"	"GO:0002931//response to ischemia;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0010332//response to gamma radiation;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0016311//dephosphorylation;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0043069//negative regulation of programmed cell death;GO:0043456//regulation of pentose-phosphate shunt;GO:0045739//positive regulation of DNA repair;GO:0045820//negative regulation of glycolytic process;GO:0060576//intestinal epithelial cell development;GO:0071279//cellular response to cobalt ion;GO:0071456//cellular response to hypoxia;GO:1901215//negative regulation of neuron death;GO:1901525//negative regulation of mitophagy;GO:1902153//regulation of response to DNA damage checkpoint signaling;GO:1903301//positive regulation of hexokinase activity;GO:1904024//negative regulation of glucose catabolic process to lactate via pyruvate;GO:2000378//negative regulation of reactive oxygen species metabolic process"	--
ENSG00000078246	13.382	14.257	13.551	14.042	13.94	14.624	755	788	600	598	690	647	TULP3	TUB like protein 3 [Source:HGNC Symbol;Acc:HGNC:12425]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0042995//cell projection;GO:0097546//ciliary base;GO:0097731//9+0 non-motile cilium	"GO:0001664//G protein-coupled receptor binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019899//enzyme binding;GO:0035091//phosphatidylinositol binding;GO:0044877//protein-containing complex binding;GO:0120160//intraciliary transport particle A binding"	"GO:0001841//neural tube formation;GO:0001843//neural tube closure;GO:0006355//regulation of transcription, DNA-templated;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0008589//regulation of smoothened signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0021904//dorsal/ventral neural tube patterning;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0021915//neural tube development;GO:0021953//central nervous system neuron differentiation;GO:0031076//embryonic camera-type eye development;GO:0042733//embryonic digit morphogenesis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048702//embryonic neurocranium morphogenesis;GO:0060173//limb development;GO:0060348//bone development;GO:0060434//bronchus morphogenesis;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0061512//protein localization to cilium;GO:0061548//ganglion development;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning"	Tub
ENSG00000078269	5.306	5.602	5.066	4.246	5.241	4.668	741	784	506	443	548	497	SYNJ2	synaptojanin 2 [Source:HGNC Symbol;Acc:HGNC:11504]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K20279;K20279;K20279	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098793//presynapse	"GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007420//brain development;GO:0019637//organophosphate metabolic process;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048488//synaptic vesicle endocytosis;GO:0061024//membrane organization	--
ENSG00000078295	0.397	0.611	0.394	0.514	0.705	0.088	9	19	12	8	14	1	ADCY2	adenylate cyclase 2 [Source:HGNC Symbol;Acc:HGNC:233]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis"	K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042;K08042	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045121//membrane raft	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding;GO:0008179//adenylate cyclase binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0019933//cAMP-mediated signaling;GO:0035556//intracellular signal transduction;GO:1904322//cellular response to forskolin	--
ENSG00000078304	41.222	40.177	34.963	33.366	34.5	35.921	2319	2156	1399	1364	1604	1429	PPP2R5C	protein phosphatase 2 regulatory subunit B'gamma [Source:HGNC Symbol;Acc:HGNC:9311]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11584;K11584;K11584;K11584;K11584;K11584;K11584;K11584	"GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016021//integral component of membrane"	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity	"GO:0006470//protein dephosphorylation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0016485//protein processing;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity"	--
ENSG00000078328	0.122	0.098	0.178	0.115	0.176	0.02	4	7	6	7	6	1	RBFOX1	RNA binding fox-1 homolog 1 [Source:HGNC Symbol;Acc:HGNC:18222]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0010494//cytoplasmic stress granule;GO:0097165//nuclear stress granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0050658//RNA transport;GO:0050885//neuromuscular process controlling balance;GO:2001014//regulation of skeletal muscle cell differentiation"	--
ENSG00000078369	107.336	106.516	104.615	105.714	104.91	106.722	6711	6784	5012	4862	5441	4871	GNB1	G protein subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4396]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Sensory system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04740//Olfactory transduction;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04744//Phototransduction	K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536;K04536	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0097381//photoreceptor disc membrane;GO:1903561//extracellular vesicle	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0044877//protein-containing complex binding;GO:0051020//GTPase binding	GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0008283//cell population proliferation;GO:0050909//sensory perception of taste;GO:0060041//retina development in camera-type eye;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071870//cellular response to catecholamine stimulus	--
ENSG00000078399	0.023	0.116	0	0	0	0	1	3	0	0	0	0	HOXA9	homeobox A9 [Source:HGNC Symbol;Acc:HGNC:5109]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K21950	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0042118//endothelial cell activation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000078401	1.919	1.673	0.802	0.832	0.729	0.944	81	71	25	26	26	29	EDN1	endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cardiovascular disease;Circulatory system;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Cardiovascular disease;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04066//HIF-1 signaling pathway;ko04668//TNF signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04916//Melanogenesis;ko05410//Hypertrophic cardiomyopathy;ko04924//Renin secretion	K16366;K16366;K16366;K16366;K16366;K16366;K16366;K16366;K16366;K16366;K16366;K16366	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0033093//Weibel-Palade body;GO:0045178//basal part of cell;GO:0048237//rough endoplasmic reticulum lumen	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031707//endothelin A receptor binding;GO:0031708//endothelin B receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001501//skeletal system development;GO:0001516//prostaglandin biosynthetic process;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001821//histamine secretion;GO:0001975//response to amphetamine;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0003357//noradrenergic neuron differentiation;GO:0006366//transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006885//regulation of pH;GO:0007005//mitochondrion organization;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007267//cell-cell signaling;GO:0007507//heart development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0007589//body fluid secretion;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009953//dorsal/ventral pattern formation;GO:0010193//response to ozone;GO:0010259//multicellular organism aging;GO:0010460//positive regulation of heart rate;GO:0010467//gene expression;GO:0010595//positive regulation of endothelial cell migration;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010629//negative regulation of gene expression;GO:0010737//protein kinase A signaling;GO:0010827//regulation of glucose transmembrane transport;GO:0014032//neural crest cell development;GO:0014033//neural crest cell differentiation;GO:0014034//neural crest cell fate commitment;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0014824//artery smooth muscle contraction;GO:0014826//vein smooth muscle contraction;GO:0019229//regulation of vasoconstriction;GO:0019233//sensory perception of pain;GO:0019722//calcium-mediated signaling;GO:0030072//peptide hormone secretion;GO:0030185//nitric oxide transport;GO:0030195//negative regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0030878//thyroid gland development;GO:0031175//neuron projection development;GO:0031583//phospholipase D-activating G protein-coupled receptor signaling pathway;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032308//positive regulation of prostaglandin secretion;GO:0032496//response to lipopolysaccharide;GO:0033574//response to testosterone;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0034696//response to prostaglandin F;GO:0035050//embryonic heart tube development;GO:0035094//response to nicotine;GO:0035556//intracellular signal transduction;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0035994//response to muscle stretch;GO:0042045//epithelial fluid transport;GO:0042310//vasoconstriction;GO:0042313//protein kinase C deactivation;GO:0042474//middle ear morphogenesis;GO:0042482//positive regulation of odontogenesis;GO:0042554//superoxide anion generation;GO:0043179//rhythmic excitation;GO:0043200//response to amino acid;GO:0043406//positive regulation of MAP kinase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0044321//response to leptin;GO:0044751//cellular response to human chorionic gonadotropin stimulus;GO:0045321//leukocyte activation;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045793//positive regulation of cell size;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045987//positive regulation of smooth muscle contraction;GO:0046887//positive regulation of hormone secretion;GO:0046888//negative regulation of hormone secretion;GO:0048016//inositol phosphate-mediated signaling;GO:0048514//blood vessel morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048675//axon extension;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051216//cartilage development;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0051899//membrane depolarization;GO:0051930//regulation of sensory perception of pain;GO:0060070//canonical Wnt signaling pathway;GO:0060137//maternal process involved in parturition;GO:0060298//positive regulation of sarcomere organization;GO:0060385//axonogenesis involved in innervation;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0061626//pharyngeal arch artery morphogenesis;GO:0065008//regulation of biological quality;GO:0070101//positive regulation of chemokine-mediated signaling pathway;GO:0070294//renal sodium ion absorption;GO:0070301//cellular response to hydrogen peroxide;GO:0070371//ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071310//cellular response to organic substance;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071389//cellular response to mineralocorticoid stimulus;GO:0071398//cellular response to fatty acid;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0071548//response to dexamethasone;GO:0071559//response to transforming growth factor beta;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0086100//endothelin receptor signaling pathway;GO:0086101//endothelin receptor signaling pathway involved in heart process;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0097492//sympathetic neuron axon guidance;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902074//response to salt;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1903537//meiotic cell cycle process involved in oocyte maturation;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000273//positive regulation of signaling receptor activity;GO:2001259//positive regulation of cation channel activity	--
ENSG00000078403	9.912	11.376	9.147	8.252	8.179	7.88	582	576	404	321	406	346	MLLT10	MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000078487	1.205	1.643	1.741	1.512	1.266	1.095	54	63	53	47	36	31	ZCWPW1	zinc finger CW-type and PWWP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23486]	-	-	-	-	GO:0001741//XY body;GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	GO:0007127//meiosis I;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045911//positive regulation of DNA recombination;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000078549	0.07	0.057	0.01	0.041	0.036	0.03	5	5	1	2	1	3	ADCYAP1R1	ADCYAP receptor type I [Source:HGNC Symbol;Acc:HGNC:242]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Environmental adaptation;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04713//Circadian entrainment;ko04911//Insulin secretion;ko04924//Renin secretion	K04587;K04587;K04587;K04587;K04587	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0031267//small GTPase binding;GO:0038023//signaling receptor activity;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007283//spermatogenesis;GO:0009410//response to xenobiotic stimulus;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0019933//cAMP-mediated signaling;GO:0030154//cell differentiation;GO:0032355//response to estradiol;GO:0033555//multicellular organismal response to stress;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045471//response to ethanol;GO:0046545//development of primary female sexual characteristics;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0060548//negative regulation of cell death;GO:0060732//positive regulation of inositol phosphate biosynthetic process	--
ENSG00000078579	0	0	0	0	0	0	0	0	0	0	0	0	FGF20	fibroblast growth factor 20 [Source:HGNC Symbol;Acc:HGNC:3677]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0090722//receptor-receptor interaction	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0014059//regulation of dopamine secretion;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060113//inner ear receptor cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1904340//positive regulation of dopaminergic neuron differentiation	--
ENSG00000078589	0	0	0	0	0	0.019	0	0	0	0	0	1	P2RY10	P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04274	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000078596	32.344	28.74	38.195	40.956	40.392	50.011	1087	970	947	1019	1145	1222	ITM2A	integral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	GO:0002317//plasma cell differentiation;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process	--
ENSG00000078618	34.222	29.721	28.999	27.27	26.18	25.832	2573	2247	1607	1514	1663	1416	NRDC	nardilysin convertase [Source:HGNC Symbol;Acc:HGNC:7995]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0009986//cell surface	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0048408//epidermal growth factor binding	GO:0006508//proteolysis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0052548//regulation of endopeptidase activity;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000078668	54.684	52.86	53.706	55.352	53.765	48.64	1535	1488	1113	1161	1267	1002	VDAC3	voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Infectious disease: viral;Cell growth and death;Neurodegenerative disease;Digestive system;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05203//Viral carcinogenesis;ko04621//NOD-like receptor signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia;ko04979//Cholesterol metabolism;ko04216//Ferroptosis	K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041;K15041	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0046930//pore complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0008308//voltage-gated anion channel activity;GO:0015288//porin activity	GO:0006811//ion transport;GO:0015698//inorganic anion transport;GO:0015853//adenine transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902017//regulation of cilium assembly	--
ENSG00000078674	15.261	9.245	9.045	5.896	7.975	8.284	1632	1027	703	459	730	670	PCM1	pericentriolar material 1 [Source:HGNC Symbol;Acc:HGNC:8727]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0045177//apical part of cell	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001764//neuron migration;GO:0007098//centrosome cycle;GO:0022027//interkinetic nuclear migration;GO:0030030//cell projection organization;GO:0031122//cytoplasmic microtubule organization;GO:0033365//protein localization to organelle;GO:0034453//microtubule anchoring;GO:0034454//microtubule anchoring at centrosome;GO:0035176//social behavior;GO:0035735//intraciliary transport involved in cilium assembly;GO:0050768//negative regulation of neurogenesis;GO:0060271//cilium assembly;GO:0071539//protein localization to centrosome;GO:0090316//positive regulation of intracellular protein transport;GO:0097150//neuronal stem cell population maintenance;GO:1905515//non-motile cilium assembly	--
ENSG00000078687	2.523	2.299	2.488	2.265	2.51	3.27	439.47	387.73	310.56	274.8	376.78	306.5	TNRC6C	trinucleotide repeat containing adaptor 6C [Source:HGNC Symbol;Acc:HGNC:29318]	-	-	-	-	GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006417//regulation of translation;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	--
ENSG00000078699	5.225	4.716	5.31	4.143	5.298	4.888	786	725.02	594	468	680	546	CBFA2T2	CBFA2/RUNX1 partner transcriptional co-repressor 2 [Source:HGNC Symbol;Acc:HGNC:1536]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006351//transcription, DNA-templated;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0030855//epithelial cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060575//intestinal epithelial cell differentiation"	--
ENSG00000078725	0.578	0.333	0.206	0.534	0.604	0.23	38	22	10	26	33	11	BRINP1	BMP/retinoic acid inducible neural specific 1 [Source:HGNC Symbol;Acc:HGNC:2687]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0005515//protein binding	GO:0001662//behavioral fear response;GO:0007049//cell cycle;GO:0007614//short-term memory;GO:0008219//cell death;GO:0035176//social behavior;GO:0035640//exploration behavior;GO:0042711//maternal behavior;GO:0045666//positive regulation of neuron differentiation;GO:0045786//negative regulation of cell cycle;GO:0045930//negative regulation of mitotic cell cycle;GO:0050768//negative regulation of neurogenesis;GO:0071300//cellular response to retinoic acid;GO:0071625//vocalization behavior	--
ENSG00000078747	19.325	16.659	17.521	10.517	13.5	21.082	1692.44	1481.18	1082.47	782.36	1018.55	1162.85	ITCH	itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890]	Cellular Processes;Human Diseases;Genetic Information Processing;Environmental Information Processing	"Transport and catabolism;Endocrine and metabolic disease;Folding, sorting and degradation;Signal transduction"	ko04144//Endocytosis;ko04932//Non-alcoholic fatty liver disease;ko04120//Ubiquitin mediated proteolysis;ko04668//TNF signaling pathway	K05632;K05632;K05632;K05632	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0043021//ribonucleoprotein complex binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0045236//CXCR chemokine receptor binding;GO:0061630//ubiquitin protein ligase activity;GO:1990763//arrestin family protein binding	GO:0000209//protein polyubiquitination;GO:0001558//regulation of cell growth;GO:0002376//immune system process;GO:0002669//positive regulation of T cell anergy;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0016567//protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032480//negative regulation of type I interferon production;GO:0035519//protein K29-linked ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0045732//positive regulation of protein catabolic process;GO:0046329//negative regulation of JNK cascade;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0046718//viral entry into host cell;GO:0050687//negative regulation of defense response to virus;GO:0051607//defense response to virus;GO:0051865//protein autoubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0090085//regulation of protein deubiquitination;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:2000646//positive regulation of receptor catabolic process	--
ENSG00000078795	0	0	0	0	0	0	0	0	0	0	0	0	PKD2L2	"polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005262//calcium channel activity;GO:0005509//calcium ion binding	GO:0006811//ion transport;GO:0008150//biological_process;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport	--
ENSG00000078804	17.699	20.148	18.632	19.767	19.902	16.436	1498	1630	1156	1235	1303	958	TP53INP2	tumor protein p53 inducible nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16104]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21247	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0016605//PML body;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0043130//ubiquitin binding	"GO:0000045//autophagosome assembly;GO:0001649//osteoblast differentiation;GO:0001894//tissue homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0010508//positive regulation of autophagy;GO:0016236//macroautophagy;GO:0045893//positive regulation of transcription, DNA-templated;GO:1903828//negative regulation of cellular protein localization"	--
ENSG00000078808	119.534	128.39	123.051	122.538	125.477	110.542	4763	5170	3629	3595	4250	3201	SDF4	stromal cell derived factor 4 [Source:HGNC Symbol;Acc:HGNC:24188]	-	-	-	-	GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032059//bleb;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006887//exocytosis;GO:0009650//UV protection;GO:0017156//calcium-ion regulated exocytosis;GO:0021549//cerebellum development;GO:0045444//fat cell differentiation;GO:0045471//response to ethanol;GO:0070625//zymogen granule exocytosis;GO:0099558//maintenance of synapse structure	--
ENSG00000078814	0.029	0.126	0	0.011	0.028	0.086	4	10	0	1	3	8	MYH7B	myosin heavy chain 7B [Source:HGNC Symbol;Acc:HGNC:15906]	-	-	-	-	GO:0016020//membrane;GO:0016459//myosin complex;GO:0032982//myosin filament;GO:0097512//cardiac myofibril	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0050848//regulation of calcium-mediated signaling;GO:0051480//regulation of cytosolic calcium ion concentration;GO:1905289//regulation of CAMKK-AMPK signaling cascade	--
ENSG00000078898	0	0	0	0	0	0	0	0	0	0	0	0	BPIFB2	BPI fold containing family B member 2 [Source:HGNC Symbol;Acc:HGNC:16177]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0008289//lipid binding	-	--
ENSG00000078900	1.363	1.04	0.679	0.125	0.28	0.305	100	89	54	10	20	11	TP73	tumor protein p73 [Source:HGNC Symbol;Acc:HGNC:12003]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes	Signal transduction;Infectious disease: viral;Nervous system;Cell growth and death	ko04390//Hippo signaling pathway;ko05162//Measles;ko04722//Neurotrophin signaling pathway;ko04115//p53 signaling pathway	K10148;K10148;K10148;K10148	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0001822//kidney development;GO:0006298//mismatch repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009410//response to xenobiotic stimulus;GO:0010243//response to organonitrogen compound;GO:0010468//regulation of gene expression;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0051262//protein tetramerization;GO:0051726//regulation of cell cycle;GO:0060044//negative regulation of cardiac muscle cell proliferation"	P53
ENSG00000078902	25.376	26.641	30.916	29.002	31.89	32.15	1831	1871	1490	1515	1847	1608	TOLLIP	toll interacting protein [Source:HGNC Symbol;Acc:HGNC:16476]	Organismal Systems	Immune system	ko04620//Toll-like receptor signaling pathway	K05402	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	"GO:0005150//interleukin-1, type I receptor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0032183//SUMO binding;GO:0035325//Toll-like receptor binding;GO:0043130//ubiquitin binding"	GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0030855//epithelial cell differentiation;GO:0033235//positive regulation of protein sumoylation;GO:0036010//protein localization to endosome;GO:0045087//innate immune response;GO:0045321//leukocyte activation;GO:0070498//interleukin-1-mediated signaling pathway	--
ENSG00000078967	10.883	11.127	14.388	11.334	8.164	9.461	398	437	303	314	280	256	UBE2D4	ubiquitin conjugating enzyme E2 D4 (putative) [Source:HGNC Symbol;Acc:HGNC:21647]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation;Folding, sorting and degradation"	ko05131//Shigellosis;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K06689;K06689;K06689	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0035519//protein K29-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination	--
ENSG00000079101	10.431	10.05	11.432	7.743	7.407	8.865	423	403	312	232	248	259	CLUL1	clusterin like 1 [Source:HGNC Symbol;Acc:HGNC:2096]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus	GO:0051787//misfolded protein binding	-	--
ENSG00000079102	4.068	2.924	3.231	3.019	2.173	2.279	201	119	116	104	155	145	RUNX1T1	RUNX1 partner transcriptional co-repressor 1 [Source:HGNC Symbol;Acc:HGNC:1535]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05221//Acute myeloid leukemia	K10053;K10053;K10053	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000079112	0	0.055	0	0	0	0	0	3	0	0	0	0	CDH17	cadherin 17 [Source:HGNC Symbol;Acc:HGNC:1756]	Human Diseases	Cancer: specific types	ko05226//Gastric cancer	K06811	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016342//catenin complex;GO:0030054//cell junction	GO:0005178//integrin binding;GO:0005215//transporter activity;GO:0005427//proton-dependent oligopeptide secondary active transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0002314//germinal center B cell differentiation;GO:0002315//marginal zone B cell differentiation;GO:0006857//oligopeptide transport;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007229//integrin-mediated signaling pathway;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030183//B cell differentiation;GO:0033626//positive regulation of integrin activation by cell surface receptor linked signal transduction;GO:0035672//oligopeptide transmembrane transport;GO:0048536//spleen development;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000079134	5.863	4.4	4.769	4.306	4.092	4.879	229	181	154	134	151	151	THOC1	THO complex 1 [Source:HGNC Symbol;Acc:HGNC:19070]	Genetic Information Processing;Genetic Information Processing	Transcription;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport	K12878;K12878	"GO:0000346//transcription export complex;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016607//nuclear speck"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000018//regulation of DNA recombination;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008380//RNA splicing;GO:0031297//replication fork processing;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0046784//viral mRNA export from host cell nucleus;GO:0048297//negative regulation of isotype switching to IgA isotypes;GO:0051028//mRNA transport;GO:2000002//negative regulation of DNA damage checkpoint"	--
ENSG00000079150	6.607	5.911	4.959	4.42	3.42	4.188	226	170	120	118	115	131	FKBP7	FKBP prolyl isomerase 7 [Source:HGNC Symbol;Acc:HGNC:3723]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0018208//peptidyl-proline modification	--
ENSG00000079156	1.929	1.796	1.782	1.778	2.075	2.21	172	170	130	133	163	140	OSBPL6	oxysterol binding protein like 6 [Source:HGNC Symbol;Acc:HGNC:16388]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0015918//sterol transport;GO:0032374//regulation of cholesterol transport	--
ENSG00000079215	1.258	0.349	0.459	0.309	0.516	0.181	25	15	7	17	11	2	SLC1A3	solute carrier family 1 member 3 [Source:HGNC Symbol;Acc:HGNC:10941]	Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Nervous system;Nervous system	ko05016//Huntington disease;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle	K05614;K05614;K05614	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0098796//membrane protein complex	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0016595//glutamate binding;GO:0016597//amino acid binding;GO:0046872//metal ion binding	GO:0001504//neurotransmitter uptake;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0006883//cellular sodium ion homeostasis;GO:0007268//chemical synaptic transmission;GO:0007605//sensory perception of sound;GO:0009410//response to xenobiotic stimulus;GO:0009416//response to light stimulus;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0009611//response to wounding;GO:0015711//organic anion transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015813//L-glutamate transmembrane transport;GO:0021545//cranial nerve development;GO:0031223//auditory behavior;GO:0046677//response to antibiotic;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050806//positive regulation of synaptic transmission;GO:0050885//neuromuscular process controlling balance;GO:0051938//L-glutamate import;GO:0055085//transmembrane transport;GO:0070633//transepithelial transport;GO:0070779//D-aspartate import across plasma membrane;GO:0071314//cellular response to cocaine;GO:0071805//potassium ion transmembrane transport;GO:0098712//L-glutamate import across plasma membrane;GO:0140009//L-aspartate import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000079246	75.955	74.387	68.381	59.043	59.897	56.936	5328	5187	3546	3068	3553	2908	XRCC5	X-ray repair cross complementing 5 [Source:HGNC Symbol;Acc:HGNC:12833]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K10885	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032040//small-subunit processome;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0034774//secretory granule lumen;GO:0043564//Ku70:Ku80 complex;GO:0070418//DNA-dependent protein kinase complex;GO:0070419//nonhomologous end joining complex;GO:0090734//site of DNA damage;GO:1990904//ribonucleoprotein complex"	"GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008047//enzyme activator activity;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0034511//U3 snoRNA binding;GO:0042162//telomeric DNA binding;GO:0044877//protein-containing complex binding;GO:0045027//DNA end binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity"	"GO:0000723//telomere maintenance;GO:0000725//recombinational repair;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0032204//regulation of telomere maintenance;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032508//DNA duplex unwinding;GO:0034462//small-subunit processome assembly;GO:0042254//ribosome biogenesis;GO:0043085//positive regulation of catalytic activity;GO:0045087//innate immune response;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048660//regulation of smooth muscle cell proliferation;GO:0050769//positive regulation of neurogenesis;GO:0051973//positive regulation of telomerase activity;GO:0060218//hematopoietic stem cell differentiation;GO:0070198//protein localization to chromosome, telomeric region;GO:0071398//cellular response to fatty acid;GO:0071475//cellular hyperosmotic salinity response;GO:0071480//cellular response to gamma radiation;GO:0071481//cellular response to X-ray;GO:1904430//negative regulation of t-circle formation;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000079257	11.209	14.446	5.851	10.088	10.603	9.502	249	322	96	166	199	153	LXN	latexin [Source:HGNC Symbol;Acc:HGNC:13347]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity	GO:0006954//inflammatory response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0050965//detection of temperature stimulus involved in sensory perception of pain	--
ENSG00000079263	0.122	0.118	0.114	0.082	0.07	0.023	8	8	2	4	4	1	SP140	SP140 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:17133]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016604//nuclear body;GO:0016605//PML body	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response	SAND
ENSG00000079277	5.957	7.511	6.982	6.75	7.613	6.17	299	293	212	232	260	187	MKNK1	MAPK interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signal transduction;Endocrine system;Signal transduction	ko04010//MAPK signaling pathway;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway	K04372;K04372;K04372	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation	--
ENSG00000079308	14.645	19.117	15.162	11.179	16.024	12.04	2143	2235	1330	1235	1720	1111	TNS1	tensin 1 [Source:HGNC Symbol;Acc:HGNC:11973]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0030054//cell junction;GO:0030055//cell-substrate junction	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding	GO:0007044//cell-substrate junction assembly;GO:0010761//fibroblast migration	--
ENSG00000079313	4.701	3.636	4.427	5.074	4.367	4.652	371	333	291	305	325	297	REXO1	RNA exonuclease 1 homolog [Source:HGNC Symbol;Acc:HGNC:24616]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14570	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0016787//hydrolase activity	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000079332	31.928	33.944	32.547	25.95	25.805	31.487	2245	2388.36	1720	1402	1545	1601	SAR1A	secretion associated Ras related GTPase 1A [Source:HGNC Symbol;Acc:HGNC:10534]	Genetic Information Processing;Human Diseases	"Folding, sorting and degradation;Infectious disease: bacterial"	ko04141//Protein processing in endoplasmic reticulum;ko05134//Legionellosis	K07953;K07953	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0030127//COPII vesicle coat;GO:0070971//endoplasmic reticulum exit site	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0003400//regulation of COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016050//vesicle organization;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000079335	1.998	1.967	1.859	1.564	1.983	1.712	157	140	110	95	112	86	CDC14A	cell division cycle 14A [Source:HGNC Symbol;Acc:HGNC:1718]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06639	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0060091//kinocilium;GO:0072686//mitotic spindle;GO:1902636//kinociliary basal body	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0007096//regulation of exit from mitosis;GO:0007605//sensory perception of sound;GO:0016311//dephosphorylation;GO:0032467//positive regulation of cytokinesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051301//cell division;GO:0060271//cilium assembly	--
ENSG00000079337	0.353	0.514	0.327	1.184	1.034	1.178	27	44	24	56	59	51	RAPGEF3	Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Immune system;Nervous system;Nervous system	ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04670//Leukocyte transendothelial migration;ko04726//Serotonergic synapse;ko04720//Long-term potentiation	K08014;K08014;K08014;K08014;K08014;K08014;K08014	GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030864//cortical actin cytoskeleton;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030552//cAMP binding	GO:0001525//angiogenesis;GO:0002250//adaptive immune response;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0008306//associative learning;GO:0019933//cAMP-mediated signaling;GO:0032486//Rap protein signal transduction;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034242//negative regulation of syncytium formation by plasma membrane fusion;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0045766//positive regulation of angiogenesis;GO:0046827//positive regulation of protein export from nucleus;GO:0050790//regulation of catalytic activity;GO:0051496//positive regulation of stress fiber assembly;GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0061028//establishment of endothelial barrier;GO:0071320//cellular response to cAMP;GO:1901985//positive regulation of protein acetylation;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000079385	0.055	0	0	0.052	0.05	0.248	4	0	0	1	3	10	CEACAM1	CEA cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1814]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031528//microvillus membrane;GO:0035579//specific granule membrane;GO:0042101//T cell receptor complex;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015125//bile acid transmembrane transporter activity;GO:0019900//kinase binding;GO:0019903//protein phosphatase binding;GO:0031005//filamin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:1990782//protein tyrosine kinase binding	"GO:0001525//angiogenesis;GO:0001558//regulation of cell growth;GO:0001568//blood vessel development;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0002859//negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0006469//negative regulation of protein kinase activity;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007229//integrin-mediated signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0015721//bile acid and bile salt transport;GO:0016477//cell migration;GO:0030334//regulation of cell migration;GO:0030853//negative regulation of granulocyte differentiation;GO:0032692//negative regulation of interleukin-1 production;GO:0032869//cellular response to insulin stimulus;GO:0035726//common myeloid progenitor cell proliferation;GO:0038016//insulin receptor internalization;GO:0038158//granulocyte colony-stimulating factor signaling pathway;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043116//negative regulation of vascular permeability;GO:0043318//negative regulation of cytotoxic T cell degranulation;GO:0044319//wound healing, spreading of cells;GO:0045601//regulation of endothelial cell differentiation;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051055//negative regulation of lipid biosynthetic process;GO:0060312//regulation of blood vessel remodeling;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0090331//negative regulation of platelet aggregation;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1901143//insulin catabolic process;GO:1903385//regulation of homophilic cell adhesion;GO:1903670//regulation of sprouting angiogenesis;GO:2000346//negative regulation of hepatocyte proliferation;GO:2001214//positive regulation of vasculogenesis"	--
ENSG00000079387	5.215	3.286	4.192	3.806	4.165	3.729	412	321	242	240	301	244	SENP1	SUMO specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:17927]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0031965//nuclear membrane	GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070139//SUMO-specific endopeptidase activity;GO:0070140//SUMO-specific isopeptidase activity	GO:0006508//proteolysis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016926//protein desumoylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097190//apoptotic signaling pathway	--
ENSG00000079393	0	0	0	0	0	0	0	0	0	0	0	0	DUSP13	dual specificity phosphatase 13 [Source:HGNC Symbol;Acc:HGNC:19681]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007283//spermatogenesis;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0051321//meiotic cell cycle	--
ENSG00000079432	54.508	55.96	60.48	62.008	63.881	65.812	5993	6296	4768	4933	6007	5132	CIC	capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K20225	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007612//learning;GO:0007613//memory;GO:0035176//social behavior;GO:0045892//negative regulation of transcription, DNA-templated"	HMG
ENSG00000079435	98.937	99.202	105.739	159.795	165.194	169.657	2918	2954	2332	3527	4038	3594	LIPE	"lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621]"	Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Environmental adaptation;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine system;Endocrine system	ko04714//Thermogenesis;ko04024//cAMP signaling pathway;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04152//AMPK signaling pathway;ko04925//Aldosterone synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes	K07188;K07188;K07188;K07188;K07188;K07188;K07188	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane	"GO:0004771//sterol esterase activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0033878//hormone-sensitive lipase activity;GO:0047372//acylglycerol lipase activity;GO:0047376//all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0050253//retinyl-palmitate esterase activity;GO:0102258//1,3-diacylglycerol acylhydrolase activity;GO:0102259//1,2-diacylglycerol acylhydrolase activity"	GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0042572//retinol metabolic process;GO:0046340//diacylglycerol catabolic process;GO:0046485//ether lipid metabolic process	--
ENSG00000079459	119.313	124.19	120.912	126.538	121.518	126.8	4762	5005	3616	3734	4084	3678	FDFT1	farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3629]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K00801;K00801	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0004310//farnesyl-diphosphate farnesyltransferase activity;GO:0004311//farnesyltranstransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046872//metal ion binding;GO:0051996//squalene synthase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008152//metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008610//lipid biosynthetic process;GO:0009058//biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0045338//farnesyl diphosphate metabolic process	--
ENSG00000079462	29.524	27.892	34.695	38.009	28.568	35.673	577.77	576.35	472.94	534.84	470.79	506.68	PAFAH1B3	platelet activating factor acetylhydrolase 1b catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:8576]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K16795;K16795	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008247//1-alkyl-2-acetylglycerophosphocholine esterase complex;GO:0016020//membrane	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0047179//platelet-activating factor acetyltransferase activity	GO:0006629//lipid metabolic process;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0007420//brain development;GO:0016042//lipid catabolic process	--
ENSG00000079482	14.391	13.725	15.813	16.588	17.025	19.015	2128.55	2046.43	1738.95	1825.57	2190.55	2038.76	OPHN1	oligophrenin 1 [Source:HGNC Symbol;Acc:HGNC:8148]	-	-	-	-	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005096//GTPase activator activity;GO:0005543//phospholipid binding;GO:0035255//ionotropic glutamate receptor binding	"GO:0006897//endocytosis;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0021707//cerebellar granule cell differentiation;GO:0021895//cerebral cortex neuron differentiation;GO:0030036//actin cytoskeleton organization;GO:0030100//regulation of endocytosis;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0034329//cell junction assembly;GO:0035023//regulation of Rho protein signal transduction;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0048488//synaptic vesicle endocytosis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050790//regulation of catalytic activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0098880//maintenance of postsynaptic specialization structure;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1901799//negative regulation of proteasomal protein catabolic process"	--
ENSG00000079557	0	0	0	0	0	0	0	0	0	0	0	0	AFM	afamin [Source:HGNC Symbol;Acc:HGNC:316]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008431//vitamin E binding	GO:0015031//protein transport;GO:0050821//protein stabilization;GO:0051180//vitamin transport;GO:0071693//protein transport within extracellular region	--
ENSG00000079616	7.169	6.559	6.946	6.792	5.828	5.715	303	293	225	229	229	189	KIF22	kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391]	Organismal Systems	Endocrine system	ko04914//Progesterone-mediated oocyte maturation	K10403	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016607//nuclear speck;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0007018//microtubule-based movement;GO:0007062//sister chromatid cohesion;GO:0007080//mitotic metaphase plate congression;GO:0051310//metaphase plate congression	--
ENSG00000079689	0	0	0	0.093	0	0	0	0	0	2	0	0	SCGN	"secretagogin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:HGNC:16941]"	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030425//dendrite;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0045202//synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1900271//regulation of long-term synaptic potentiation	--
ENSG00000079691	6.745	6.489	7.034	5.257	5.575	6.961	759	742	591	443	531	573	CARMIL1	capping protein regulator and myosin 1 linker 1 [Source:HGNC Symbol;Acc:HGNC:21581]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0031252//cell leading edge;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0044354//macropinosome;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0030335//positive regulation of cell migration;GO:0030838//positive regulation of actin filament polymerization;GO:0031529//ruffle organization;GO:0044351//macropinocytosis;GO:0046415//urate metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0051638//barbed-end actin filament uncapping;GO:0051639//actin filament network formation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902745//positive regulation of lamellipodium organization;GO:2000813//negative regulation of barbed-end actin filament capping	--
ENSG00000079739	30.913	31.546	32.201	32.501	31.757	31.5	1499	1537	1153	1167	1301	1111	PGM1	phosphoglucomutase 1 [Source:HGNC Symbol;Acc:HGNC:8905]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism;ko00030//Pentose phosphate pathway	K01835;K01835;K01835;K01835;K01835;K01835;K01835	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	"GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0019318//hexose metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000079785	34.943	33.601	35.296	26.429	25.243	30.156	1818	1746	1355	1018	1113	1140	DDX1	DEAD-box helicase 1 [Source:HGNC Symbol;Acc:HGNC:2734]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0071920//cleavage body;GO:0072669//tRNA-splicing ligase complex;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008143//poly(A) binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0033677//DNA/RNA helicase activity	"GO:0000245//spliceosomal complex assembly;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0006446//regulation of translational initiation;GO:0008033//tRNA processing;GO:0009615//response to virus;GO:0032508//DNA duplex unwinding;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1903608//protein localization to cytoplasmic stress granule"	--
ENSG00000079805	49.044	50.264	54.737	57.728	54.335	52.798	3232	3306.03	2618	2748.2	3080.01	2524	DNM2	dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]	Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Signal transduction;Immune system;Infectious disease: bacterial;Nervous system;Excretory system	ko05132//Salmonella infection;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K23484;K23484;K23484;K23484;K23484;K23484;K23484	"GO:0000139//Golgi membrane;GO:0001891//phagocytic cup;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030426//growth cone;GO:0030496//midbody;GO:0030666//endocytic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031749//D2 dopamine receptor binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0044877//protein-containing complex binding;GO:0050699//WW domain binding;GO:0050998//nitric-oxide synthase binding	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0002031//G protein-coupled receptor internalization;GO:0006355//regulation of transcription, DNA-templated;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006893//Golgi to plasma membrane transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0009416//response to light stimulus;GO:0010592//positive regulation of lamellipodium assembly;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030516//regulation of axon extension;GO:0031623//receptor internalization;GO:0033572//transferrin transport;GO:0035020//regulation of Rac protein signal transduction;GO:0042220//response to cocaine;GO:0043065//positive regulation of apoptotic process;GO:0044351//macropinocytosis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045807//positive regulation of endocytosis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048488//synaptic vesicle endocytosis;GO:0048489//synaptic vesicle transport;GO:0048812//neuron projection morphogenesis;GO:0050766//positive regulation of phagocytosis;GO:0061024//membrane organization;GO:0071245//cellular response to carbon monoxide;GO:0071481//cellular response to X-ray;GO:0071732//cellular response to nitric oxide;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902856//negative regulation of non-motile cilium assembly;GO:1903351//cellular response to dopamine;GO:1903358//regulation of Golgi organization;GO:1903408//positive regulation of P-type sodium:potassium-exchanging transporter activity;GO:1903526//negative regulation of membrane tubulation;GO:2000370//positive regulation of clathrin-dependent endocytosis"	--
ENSG00000079819	11.453	12.208	11.677	7.572	9.611	9.489	1003	1065	718	483	695	542	EPB41L2	erythrocyte membrane protein band 4.1 like 2 [Source:HGNC Symbol;Acc:HGNC:3379]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0008180//COP9 signalosome;GO:0016020//membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0030507//spectrin binding;GO:0042731//PH domain binding	GO:0007049//cell cycle;GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0051301//cell division;GO:1904778//positive regulation of protein localization to cell cortex	--
ENSG00000079841	1.626	1.533	1.203	1.118	1.873	1.597	147	127	93	77	135	125	RIMS1	regulating synaptic membrane exocytosis 1 [Source:HGNC Symbol;Acc:HGNC:17282]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04723//Retrograde endocannabinoid signaling;ko04721//Synaptic vesicle cycle	K15291;K15291	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030695//GTPase regulator activity;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0006836//neurotransmitter transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0007601//visual perception;GO:0010628//positive regulation of gene expression;GO:0016079//synaptic vesicle exocytosis;GO:0017156//calcium-ion regulated exocytosis;GO:0030154//cell differentiation;GO:0042391//regulation of membrane potential;GO:0045055//regulated exocytosis;GO:0046903//secretion;GO:0046928//regulation of neurotransmitter secretion;GO:0048167//regulation of synaptic plasticity;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0050790//regulation of catalytic activity;GO:0050806//positive regulation of synaptic transmission;GO:0050896//response to stimulus;GO:0060478//acrosomal vesicle exocytosis;GO:0061025//membrane fusion;GO:0065003//protein-containing complex assembly;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:1903861//positive regulation of dendrite extension;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000079931	0.556	0.578	0.175	0.199	0.267	0.022	34	36	8	9	14	1	MOXD1	monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	"GO:0003824//catalytic activity;GO:0004497//monooxygenase activity;GO:0004500//dopamine beta-monooxygenase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0046872//metal ion binding"	GO:0006589//octopamine biosynthetic process;GO:0042420//dopamine catabolic process;GO:0042421//norepinephrine biosynthetic process	--
ENSG00000079950	16.942	18.119	17.68	15.313	14.514	18.48	1502	1427	1081	946	1024	1022	STX7	syntaxin 7 [Source:HGNC Symbol;Acc:HGNC:11442]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04145//Phagosome;ko04130//SNARE interactions in vesicular transport	K08488;K08488	GO:0001772//immunological synapse;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0031201//SNARE complex;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0042582//azurophil granule;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0070820//tertiary granule	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019869//chloride channel inhibitor activity;GO:0019905//syntaxin binding	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0048278//vesicle docking;GO:0051640//organelle localization;GO:0070925//organelle assembly;GO:1902685//positive regulation of receptor localization to synapse;GO:1903076//regulation of protein localization to plasma membrane	--
ENSG00000079974	9.253	8.911	8.393	8.918	9.332	8.992	408.69	412.66	286.55	305.8	346.44	306.18	RABL2B	"RAB, member of RAS oncogene family like 2B [Source:HGNC Symbol;Acc:HGNC:9800]"	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0012505//endomembrane system;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0030030//cell projection organization;GO:0042073//intraciliary transport;GO:0060271//cilium assembly	--
ENSG00000079999	29.587	31.194	34.539	32.457	32.022	33.966	1534	1680	1350	1273	1446	1330	KEAP1	kelch like ECH associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23177]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases	"Cancer: overview;Neurodegenerative disease;Cancer: overview;Cancer: specific types;Folding, sorting and degradation;Cardiovascular disease"	ko05200//Pathways in cancer;ko05012//Parkinson disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05225//Hepatocellular carcinoma;ko04120//Ubiquitin mediated proteolysis;ko05418//Fluid shear stress and atherosclerosis	K10456;K10456;K10456;K10456;K10456;K10456	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005884//actin filament;GO:0016234//inclusion body;GO:0030496//midbody;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042802//identical protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097718//disordered domain specific binding	"GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010506//regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034599//cellular response to oxidative stress;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045604//regulation of epidermal cell differentiation;GO:0071353//cellular response to interleukin-4"	--
ENSG00000080007	0	0	0	0	0	0	0	0	0	0	0	0	DDX43	DEAD-box helicase 43 [Source:HGNC Symbol;Acc:HGNC:18677]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000080031	0.263	0.416	0.283	0.647	0.465	0.557	20	34	17	39	32	33	PTPRH	protein tyrosine phosphatase receptor type H [Source:HGNC Symbol;Acc:HGNC:9672]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0045296//cadherin binding	GO:0006470//protein dephosphorylation;GO:0006915//apoptotic process;GO:0016311//dephosphorylation;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000080166	891.882	761.744	767.854	658.045	712.311	862.161	91324	78229	58518	50403	60916	64110	DCT	dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Amino acid metabolism	ko01100//Metabolic pathways;ko04916//Melanogenesis;ko00350//Tyrosine metabolism	K01827;K01827;K01827	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle	GO:0004167//dopachrome isomerase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0002052//positive regulation of neuroblast proliferation;GO:0006583//melanin biosynthetic process from tyrosine;GO:0008544//epidermis development;GO:0009637//response to blue light;GO:0021847//ventricular zone neuroblast division;GO:0042438//melanin biosynthetic process;GO:0043473//pigmentation;GO:0048066//developmental pigmentation;GO:0048468//cell development	--
ENSG00000080189	18.533	18.644	19.36	23.418	23.277	21.32	996	1002	756	928	1029	823	SLC35C2	solute carrier family 35 member C2 [Source:HGNC Symbol;Acc:HGNC:17117]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0010629//negative regulation of gene expression;GO:0015786//UDP-glucose transmembrane transport;GO:0036065//fucosylation;GO:0036066//protein O-linked fucosylation;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000080200	2.554	1.466	1.089	0.864	1.291	1.465	571.02	329.4	179.81	143.17	243.77	238.36	CRYBG3	crystallin beta-gamma domain containing 3 [Source:HGNC Symbol;Acc:HGNC:34427]	-	-	-	-	GO:0032991//protein-containing complex	GO:0005212//structural constituent of eye lens;GO:0030246//carbohydrate binding;GO:0051018//protein kinase A binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0008150//biological_process	--
ENSG00000080224	0.324	0.434	0.133	0.283	0.194	0.322	18	12	3	8	7	6	EPHA6	EPH receptor A6 [Source:HGNC Symbol;Acc:HGNC:19296]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05107	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0008150//biological_process;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000080293	0.026	0.026	0	0.035	0.031	0.071	1	1	0	1	1	2	SCTR	secretin receptor [Source:HGNC Symbol;Acc:HGNC:10608]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Digestive system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04972//Pancreatic secretion;ko04976//Bile secretion	K04588;K04588;K04588	GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0015055//secretin receptor activity;GO:0017046//peptide hormone binding	GO:0002024//diet induced thermogenesis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0009992//cellular water homeostasis;GO:0031667//response to nutrient levels;GO:0032098//regulation of appetite;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0048167//regulation of synaptic plasticity	--
ENSG00000080298	4.429	2.99	3.993	2.006	2.887	2.992	644	485	391	231	372	333	RFX3	regulatory factor X3 [Source:HGNC Symbol;Acc:HGNC:9984]	-	-	-	-	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0030154//cell differentiation;GO:0031018//endocrine pancreas development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0050796//regulation of insulin secretion;GO:0060271//cilium assembly;GO:0060285//cilium-dependent cell motility;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0072560//type B pancreatic cell maturation;GO:2000078//positive regulation of type B pancreatic cell development"	RFX
ENSG00000080345	3.388	1.701	1.756	0.977	1.781	1.788	773	369	294	180	324	307	RIF1	replication timing regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:23207]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11138	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0031965//nuclear membrane;GO:0035861//site of double-strand break;GO:0051233//spindle midzone;GO:0140445//chromosome, telomeric repeat region"	GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0019827//stem cell population maintenance;GO:0031509//subtelomeric heterochromatin assembly;GO:0043247//telomere maintenance in response to DNA damage;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045830//positive regulation of isotype switching;GO:0051052//regulation of DNA metabolic process;GO:0051574//positive regulation of histone H3-K9 methylation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000080371	4.019	2.812	3.222	2.677	2.751	3.288	1297	912	768	640	750	772	RAB21	"RAB21, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18263]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0009898//cytoplasmic side of plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032154//cleavage furrow;GO:0032580//Golgi cisterna membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098559//cytoplasmic side of early endosome membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0030516//regulation of axon extension;GO:0032482//Rab protein signal transduction;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050821//protein stabilization;GO:2000643//positive regulation of early endosome to late endosome transport	--
ENSG00000080493	10.472	8.492	6.598	7.455	8.931	8.13	1405	1317	718	852	1128	896	SLC4A4	solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030]	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Excretory system	ko04972//Pancreatic secretion;ko04976//Bile secretion;ko04964//Proximal tubule bicarbonate reclamation	K13575;K13575;K13575	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0044214//spanning component of plasma membrane;GO:0070062//extracellular exosome	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0035725//sodium ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0042391//regulation of membrane potential;GO:0045821//positive regulation of glycolytic process;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000080503	41.387	38.984	41.618	27.152	31.526	33.96	2778	2589	1950	1377	1785	1435	SMARCA2	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Source:HGNC Symbol;Acc:HGNC:11098]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11647;K11647	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016514//SWI/SNF complex;GO:0035060//brahma complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton;GO:0070603//SWI/SNF superfamily-type complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex;GO:0140288//GBAF complex	"GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007286//spermatid development;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030308//negative regulation of cell growth;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000080511	0	0	0	0	0	0	0	0	0	0	0	0	RDH8	retinol dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:14423]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11150;K11150	GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0052650//NADP-retinol dehydrogenase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0007601//visual perception;GO:0042572//retinol metabolic process;GO:0050896//response to stimulus	--
ENSG00000080546	3.899	3.415	2.112	2.62	2.525	3.305	286	257	125	148	162	181	SESN1	sestrin 1 [Source:HGNC Symbol;Acc:HGNC:21595]	Organismal Systems;Cellular Processes	Aging;Cell growth and death	ko04211//Longevity regulating pathway;ko04115//p53 signaling pathway	K10141;K10141	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0061700//GATOR2 complex	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0070728//leucine binding"	GO:0016239//positive regulation of macroautophagy;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0071233//cellular response to leucine;GO:0072593//reactive oxygen species metabolic process;GO:0098869//cellular oxidant detoxification;GO:1901031//regulation of response to reactive oxygen species;GO:1904262//negative regulation of TORC1 signaling;GO:1990253//cellular response to leucine starvation	--
ENSG00000080561	4.33	4.359	3.856	3.99	4.148	3.707	425	440	263	284	317	287	MID2	midline 2 [Source:HGNC Symbol;Acc:HGNC:7096]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070062//extracellular exosome	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding	"GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:0035372//protein localization to microtubule;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity"	--
ENSG00000080572	0	0.146	0	0	0	0	0	5	0	0	0	0	DNAAF6	dynein axonemal assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:28570]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding;GO:0051087//chaperone binding	GO:0003341//cilium movement;GO:0030317//flagellated sperm motility;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0070286//axonemal dynein complex assembly	--
ENSG00000080573	0	0.008	0	0.01	0.009	0.011	0	1	0	1	1	1	COL5A3	collagen type V alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:14864]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005588//collagen type V trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0043394//proteoglycan binding	GO:0007160//cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0043588//skin development	--
ENSG00000080603	19.707	24.532	25.862	24.838	25.909	24.031	2735.81	3016.02	2390.82	2119.32	2678.85	2183.67	SRCAP	Snf2 related CREBBP activator protein [Source:HGNC Symbol;Acc:HGNC:16974]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004386//helicase activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0140658//ATP-dependent chromatin remodeler activity	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0043486//histone exchange;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000080608	5.952	6.316	4.686	3.72	3.757	4.757	270	288	157	125	144	157	PUM3	pumilio RNA binding family member 3 [Source:HGNC Symbol;Acc:HGNC:29676]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0010835//regulation of protein ADP-ribosylation	--
ENSG00000080618	0	0	0	0	0	0	0	0	0	0	0	0	CPB2	carboxypeptidase B2 [Source:HGNC Symbol;Acc:HGNC:2300]	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Immune system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04610//Complement and coagulation cascades	K01300;K01300;K01300	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009408//response to heat;GO:0009410//response to xenobiotic stimulus;GO:0010757//negative regulation of plasminogen activation;GO:0042730//fibrinolysis;GO:0051918//negative regulation of fibrinolysis;GO:0071333//cellular response to glucose stimulus;GO:0097421//liver regeneration;GO:2000346//negative regulation of hepatocyte proliferation	--
ENSG00000080644	319.774	324.343	312.351	273.995	300.106	319.41	17851	17897	12791	11349	13791	13018	CHRNA3	cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Cancer: overview;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse	K04805;K04805;K04805	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044853//plasma membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding	"GO:0006811//ion transport;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007399//nervous system development;GO:0007626//locomotory behavior;GO:0014056//regulation of acetylcholine secretion, neurotransmission;GO:0034220//ion transmembrane transport;GO:0035095//behavioral response to nicotine;GO:0042391//regulation of membrane potential;GO:0048814//regulation of dendrite morphogenesis;GO:0050877//nervous system process;GO:0060079//excitatory postsynaptic potential;GO:0060084//synaptic transmission involved in micturition;GO:0095500//acetylcholine receptor signaling pathway;GO:1905144//response to acetylcholine"	--
ENSG00000080709	0.378	0.649	0.506	0.314	0.341	0.48	19	27	15	11	15	20	KCNN2	potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Nervous system;Digestive system;Endocrine system;Endocrine system	ko04726//Serotonergic synapse;ko04976//Bile secretion;ko04911//Insulin secretion;ko04929//GnRH secretion	K04943;K04943;K04943;K04943	GO:0005790//smooth endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine	GO:0005242//inward rectifier potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0051393//alpha-actinin binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000080802	8.753	8.031	7.202	7.433	7.611	7.942	602	545	358	358	417	386	CNOT4	CCR4-NOT transcription complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:7880]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K10643	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030014//CCR4-NOT complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0045652//regulation of megakaryocyte differentiation;GO:0051865//protein autoubiquitination	--
ENSG00000080815	51.671	49.175	53.231	45.911	47.185	47.014	3245	3251	2458	2148	2513	2205	PSEN1	presenilin 1 [Source:HGNC Symbol;Acc:HGNC:9508]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko04722//Neurotrophin signaling pathway;ko04330//Notch signaling pathway	K04505;K04505;K04505;K04505;K04505;K04505	GO:0000139//Golgi membrane;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016235//aggresome;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0031901//early endosome membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0035253//ciliary rootlet;GO:0035577//azurophil granule membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043198//dendritic shaft;GO:0043227//membrane-bounded organelle;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070765//gamma-secretase complex;GO:0097060//synaptic membrane;GO:0099056//integral component of presynaptic membrane	"GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0030165//PDZ domain binding;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0045296//cadherin binding;GO:0051117//ATPase binding;GO:0070851//growth factor receptor binding"	"GO:0000045//autophagosome assembly;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001708//cell fate specification;GO:0001756//somitogenesis;GO:0001764//neuron migration;GO:0001921//positive regulation of receptor recycling;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0001947//heart looping;GO:0002038//positive regulation of L-glutamate import across plasma membrane;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002265//astrocyte activation involved in immune response;GO:0002286//T cell activation involved in immune response;GO:0002573//myeloid leukocyte differentiation;GO:0003407//neural retina development;GO:0006469//negative regulation of protein kinase activity;GO:0006486//protein glycosylation;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006816//calcium ion transport;GO:0006839//mitochondrial transport;GO:0006874//cellular calcium ion homeostasis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007155//cell adhesion;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0007420//brain development;GO:0007507//heart development;GO:0007611//learning or memory;GO:0007613//memory;GO:0009791//post-embryonic development;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010975//regulation of neuron projection development;GO:0015031//protein transport;GO:0015871//choline transport;GO:0016080//synaptic vesicle targeting;GO:0016485//protein processing;GO:0021549//cerebellum development;GO:0021795//cerebral cortex cell migration;GO:0021870//Cajal-Retzius cell differentiation;GO:0021904//dorsal/ventral neural tube patterning;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0030182//neuron differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030900//forebrain development;GO:0032092//positive regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034205//amyloid-beta formation;GO:0035282//segmentation;GO:0035556//intracellular signal transduction;GO:0040011//locomotion;GO:0042307//positive regulation of protein import into nucleus;GO:0042325//regulation of phosphorylation;GO:0042327//positive regulation of phosphorylation;GO:0042982//amyloid precursor protein metabolic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043011//myeloid dendritic cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043393//regulation of protein binding;GO:0043406//positive regulation of MAP kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043589//skin morphogenesis;GO:0044267//cellular protein metabolic process;GO:0045821//positive regulation of glycolytic process;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048143//astrocyte activation;GO:0048167//regulation of synaptic plasticity;GO:0048538//thymus development;GO:0048666//neuron development;GO:0048705//skeletal system morphogenesis;GO:0048854//brain morphogenesis;GO:0050435//amyloid-beta metabolic process;GO:0050673//epithelial cell proliferation;GO:0050771//negative regulation of axonogenesis;GO:0050808//synapse organization;GO:0050820//positive regulation of coagulation;GO:0050852//T cell receptor signaling pathway;GO:0051208//sequestering of calcium ion;GO:0051402//neuron apoptotic process;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051563//smooth endoplasmic reticulum calcium ion homeostasis;GO:0051604//protein maturation;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060075//regulation of resting membrane potential;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060999//positive regulation of dendritic spine development;GO:0070588//calcium ion transmembrane transport;GO:0090647//modulation of age-related behavioral decline;GO:0098609//cell-cell adhesion;GO:0098712//L-glutamate import across plasma membrane;GO:1904646//cellular response to amyloid-beta;GO:1904797//negative regulation of core promoter binding;GO:1905908//positive regulation of amyloid fibril formation;GO:1990535//neuron projection maintenance;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000080819	3.506	2.975	2.506	2.74	3.097	3.816	177	168	104	107	147	156	CPOX	coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K00228;K00228	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004109//coproporphyrinogen oxidase activity;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process	--
ENSG00000080822	28.096	26.077	27.679	23.159	27.892	30.092	1162	1051	845	695	917	890	CLDND1	claudin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1322]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding	-	--
ENSG00000080823	7.169	7.078	8.756	6.204	5.915	5.631	207	198	156	102	129	112	MOK	MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0051726//regulation of cell cycle	--
ENSG00000080824	250.642	234.254	215.704	147.263	169.19	169.825	16736	15734	10527	7247	9558	8209	HSP90AA1	heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Genetic Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	"Cancer: overview;Signal transduction;Infectious disease: bacterial;Cardiovascular disease;Cancer: overview;Immune system;Folding, sorting and degradation;Cell growth and death;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Cancer: specific types;Immune system;Immune system"	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko04621//NOD-like receptor signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04217//Necroptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04659//Th17 cell differentiation;ko05215//Prostate cancer;ko04657//IL-17 signaling pathway;ko04612//Antigen processing and presentation	K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0043202//lysosomal lumen;GO:0043209//myelin sheath;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0023026//MHC class II protein complex binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0030911//TPR domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0048156//tau protein binding;GO:0051020//GTPase binding;GO:0051082//unfolded protein binding;GO:0070182//DNA polymerase binding;GO:0097110//scaffold protein binding;GO:0097718//disordered domain specific binding;GO:1990782//protein tyrosine kinase binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0006457//protein folding;GO:0006839//mitochondrial transport;GO:0006986//response to unfolded protein;GO:0007004//telomere maintenance via telomerase;GO:0009408//response to heat;GO:0009409//response to cold;GO:0021955//central nervous system neuron axonogenesis;GO:0030010//establishment of cell polarity;GO:0031396//regulation of protein ubiquitination;GO:0032273//positive regulation of protein polymerization;GO:0032728//positive regulation of interferon-beta production;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034605//cellular response to heat;GO:0042026//protein refolding;GO:0042981//regulation of apoptotic process;GO:0043254//regulation of protein-containing complex assembly;GO:0043335//protein unfolding;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0046677//response to antibiotic;GO:0048675//axon extension;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:0051131//chaperone-mediated protein complex assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051973//positive regulation of telomerase activity;GO:0061684//chaperone-mediated autophagy;GO:0098586//cellular response to virus;GO:1902949//positive regulation of tau-protein kinase activity;GO:1903364//positive regulation of cellular protein catabolic process;GO:1905323//telomerase holoenzyme complex assembly	--
ENSG00000080839	1.419	0.809	0.769	0.664	1.124	1.064	149	93	67	58	75	79	RBL1	RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Cell growth and death;Cell growth and death;Signal transduction	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis;ko04218//Cellular senescence;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway	K04681;K04681;K04681;K04681;K04681	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:1990841//promoter-specific chromatin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0043550//regulation of lipid kinase activity;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000773//negative regulation of cellular senescence	--
ENSG00000080845	32.227	33.648	30.283	34.19	34.032	32.345	1863	1960	1288	1452	1669	1347	DLGAP4	DLG associated protein 4 [Source:HGNC Symbol;Acc:HGNC:24476]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031594//neuromuscular junction;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0098981//cholinergic synapse;GO:0099572//postsynaptic specialization	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0023052//signaling;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000080854	3.36	3.5	3.63	2.372	2.638	3.296	911	806	604	492	689	666	IGSF9B	immunoglobulin superfamily member 9B [Source:HGNC Symbol;Acc:HGNC:32326]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:0099629//postsynaptic specialization of symmetric synapse	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007399//nervous system development	--
ENSG00000080910	0	0	0	0	0	0	0	0	0	0	0	0	CFHR2	complement factor H related 2 [Source:HGNC Symbol;Acc:HGNC:4890]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K23815	GO:0005576//extracellular region;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032091//negative regulation of protein binding;GO:0051838//cytolysis by host of symbiont cells	--
ENSG00000080986	0.658	0.429	0.43	0.276	0.429	0.249	29	19	14	9	16	8	NDC80	NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031262//Ndc80 complex;GO:0031617//NMS complex;GO:0043232//intracellular non-membrane-bounded organelle"	GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0042802//identical protein binding;GO:0140483//kinetochore adaptor activity	GO:0000070//mitotic sister chromatid segregation;GO:0000132//establishment of mitotic spindle orientation;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007057//spindle assembly involved in female meiosis I;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008315//G2/MI transition of meiotic cell cycle;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0031647//regulation of protein stability;GO:0051298//centrosome duplication;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051383//kinetochore organization;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1905342//positive regulation of protein localization to kinetochore	--
ENSG00000081014	2.423	1.252	1.846	1.429	1.557	1.72	330	176	177	148	184	175	AP4E1	adaptor related protein complex 4 subunit epsilon 1 [Source:HGNC Symbol;Acc:HGNC:573]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12400	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030124//AP-4 adaptor complex;GO:0031904//endosome lumen;GO:0032588//trans-Golgi network membrane;GO:0097708//intracellular vesicle	GO:0005515//protein binding;GO:0140312//cargo adaptor activity	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0006898//receptor-mediated endocytosis;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000081019	6.517	4.592	5.526	5.542	4.849	6.073	702	498	393	400	376	438	RSBN1	round spermatid basic protein 1 [Source:HGNC Symbol;Acc:HGNC:25642]	-	-	-	-	GO:0005634//nucleus	GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0006325//chromatin organization	--
ENSG00000081026	2.42	2.07	1.7	1.252	1.627	1.431	345	296	179	129	196	136	MAGI3	"membrane associated guanylate kinase, WW and PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29647]"	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K06112	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0060090//molecular adaptor activity	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0046037//GMP metabolic process;GO:0046328//regulation of JNK cascade;GO:0046710//GDP metabolic process	--
ENSG00000081041	0	0	0	0	0	0	0	0	0	0	0	0	CXCL2	C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: parasitic;Immune disease;Endocrine and metabolic disease;Signal transduction;Signaling molecules and interaction;Immune system;Infectious disease: bacterial;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko05323//Rheumatoid arthritis;ko04936//Alcoholic liver disease;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05134//Legionellosis	K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0045236//CXCR chemokine receptor binding	GO:0002237//response to molecule of bacterial origin;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009605//response to external stimulus;GO:0030593//neutrophil chemotaxis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000081051	0	0.02	0	0	0.047	0	0	1	0	0	2	0	AFP	alpha fetoprotein [Source:HGNC Symbol;Acc:HGNC:317]	Environmental Information Processing	Signal transduction	ko04390//Hippo signaling pathway	K16144	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen	GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001542//ovulation from ovarian follicle;GO:0019953//sexual reproduction;GO:0042448//progesterone metabolic process;GO:0060395//SMAD protein signal transduction	--
ENSG00000081052	5.654	4.932	6.35	3.722	5.715	6.715	1032	908	785	571	779	752	COL4A4	collagen type IV alpha 4 chain [Source:HGNC Symbol;Acc:HGNC:2206]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0030198//extracellular matrix organization;GO:0032836//glomerular basement membrane development	--
ENSG00000081059	17.306	16.15	17.152	16.274	16.943	18.644	994	962	781	723	851	756	TCF7	transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05132//Salmonella infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04916//Melanogenesis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620;K02620	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:1990907//beta-catenin-TCF complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006955//immune response;GO:0016055//Wnt signaling pathway;GO:0033153//T cell receptor V(D)J recombination;GO:0042492//gamma-delta T cell differentiation;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060070//canonical Wnt signaling pathway;GO:0071353//cellular response to interleukin-4"	HMG
ENSG00000081087	35.067	28.59	33.482	24.558	25.943	31.863	3252	2665	2010	1687	1914	2150	OSTM1	osteoclastogenesis associated transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:21652]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0005515//protein binding	GO:0030316//osteoclast differentiation;GO:0030321//transepithelial chloride transport	--
ENSG00000081138	0.189	0.25	0.102	0.277	0.17	0.293	22	16	8	22	9	18	CDH7	cadherin 7 [Source:HGNC Symbol;Acc:HGNC:1766]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000081148	0.035	0.023	0.039	0.039	0.034	0.04	6	4	5	5	5	5	IMPG2	interphotoreceptor matrix proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:18362]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0033165//interphotoreceptor matrix;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0071944//cell periphery	GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding;GO:0008201//heparin binding	GO:0007601//visual perception;GO:0008104//protein localization;GO:0030198//extracellular matrix organization;GO:0060042//retina morphogenesis in camera-type eye	--
ENSG00000081154	38.114	32.512	34.789	25.361	26.945	32.887	1731	1451	1131	809	1027	1045	PCNP	PEST proteolytic signal containing nuclear protein [Source:HGNC Symbol;Acc:HGNC:30023]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000081177	11.748	11.413	13.105	11.636	12.738	13.161	847	871	683	634	782	681	EXD2	exonuclease 3'-5' domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20217]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045111//intermediate filament cytoskeleton;GO:0090734//site of DNA damage	GO:0000175//3'-5'-exoribonuclease activity;GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008852//exodeoxyribonuclease I activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0000724//double-strand break repair via homologous recombination;GO:0000729//DNA double-strand break processing;GO:0006139//nucleobase-containing compound metabolic process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000081181	2.237	1.892	3.495	1.751	1.163	3.931	88.66	75.37	102.33	51.42	38.94	113.36	ARG2	arginase 2 [Source:HGNC Symbol;Acc:HGNC:664]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: parasitic;Global and overview maps;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko05146//Amoebiasis;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism;ko00220//Arginine biosynthesis	K01476;K01476;K01476;K01476;K01476	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0004053//arginase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0030145//manganese ion binding;GO:0046872//metal ion binding"	"GO:0000050//urea cycle;GO:0001657//ureteric bud development;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002829//negative regulation of type 2 immune response;GO:0006525//arginine metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0006941//striated muscle contraction;GO:0019547//arginine catabolic process to ornithine;GO:0032651//regulation of interleukin-1 beta production;GO:0032696//negative regulation of interleukin-13 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045087//innate immune response;GO:0071641//negative regulation of macrophage inflammatory protein 1 alpha production;GO:0071644//negative regulation of chemokine (C-C motif) ligand 4 production;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:1900425//negative regulation of defense response to bacterium;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1905403//negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000774//positive regulation of cellular senescence"	--
ENSG00000081189	2.42	2.231	1.332	1.275	2.629	2.165	168	179	56	78	142	75	MEF2C	myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Cancer: overview;Signal transduction;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system	"ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04928//Parathyroid hormone synthesis, secretion and action"	K04454;K04454;K04454;K04454;K04454;K04454;K04454	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016528//sarcoplasm;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0098794//postsynapse	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001568//blood vessel development;GO:0001649//osteoblast differentiation;GO:0001764//neuron migration;GO:0001782//B cell homeostasis;GO:0001947//heart looping;GO:0001958//endochondral ossification;GO:0001974//blood vessel remodeling;GO:0002062//chondrocyte differentiation;GO:0002467//germinal center formation;GO:0002634//regulation of germinal center formation;GO:0002931//response to ischemia;GO:0003138//primary heart field specification;GO:0003139//secondary heart field specification;GO:0003151//outflow tract morphogenesis;GO:0003185//sinoatrial valve morphogenesis;GO:0003211//cardiac ventricle formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0007399//nervous system development;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0007521//muscle cell fate determination;GO:0007611//learning or memory;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0014033//neural crest cell differentiation;GO:0014902//myotube differentiation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030220//platelet formation;GO:0030279//negative regulation of ossification;GO:0030318//melanocyte differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030890//positive regulation of B cell proliferation;GO:0035984//cellular response to trichostatin A;GO:0042100//B cell proliferation;GO:0043406//positive regulation of MAP kinase activity;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045652//regulation of megakaryocyte differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046928//regulation of neurotransmitter secretion;GO:0048167//regulation of synaptic plasticity;GO:0048513//animal organ development;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048666//neuron development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050853//B cell receptor signaling pathway;GO:0051145//smooth muscle cell differentiation;GO:0051963//regulation of synapse assembly;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060025//regulation of synaptic activity;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060079//excitatory postsynaptic potential;GO:0060998//regulation of dendritic spine development;GO:0061333//renal tubule morphogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0071277//cellular response to calcium ion;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0071498//cellular response to fluid shear stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072102//glomerulus morphogenesis;GO:0072160//nephron tubule epithelial cell differentiation;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration;GO:1905563//negative regulation of vascular endothelial cell proliferation;GO:2000111//positive regulation of macrophage apoptotic process;GO:2000310//regulation of NMDA receptor activity;GO:2000311//regulation of AMPA receptor activity;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:2000987//positive regulation of behavioral fear response;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis;GO:2001016//positive regulation of skeletal muscle cell differentiation"	SRF
ENSG00000081237	0.061	0.218	0.036	0.027	0.072	0.014	6	14	2	2	6	1	PTPRC	protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Immune disease;Immune system	ko05132//Salmonella infection;ko04666//Fc gamma R-mediated phagocytosis;ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04660//T cell receptor signaling pathway	K06478;K06478;K06478;K06478;K06478	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0032059//bleb;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098857//membrane microdomain	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0030506//ankyrin binding;GO:0030507//spectrin binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0001779//natural killer cell differentiation;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002639//positive regulation of immunoglobulin production;GO:0002711//positive regulation of T cell mediated immunity;GO:0002923//regulation of humoral immune response mediated by circulating immunoglobulin;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006469//negative regulation of protein kinase activity;GO:0006470//protein dephosphorylation;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007159//leukocyte cell-cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0010332//response to gamma radiation;GO:0010468//regulation of gene expression;GO:0016311//dephosphorylation;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0031668//cellular response to extracellular stimulus;GO:0031953//negative regulation of protein autophosphorylation;GO:0032677//regulation of interleukin-8 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034113//heterotypic cell-cell adhesion;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042098//T cell proliferation;GO:0042100//B cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0044770//cell cycle phase transition;GO:0044855//plasma membrane raft distribution;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0045582//positive regulation of T cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0048539//bone marrow development;GO:0048864//stem cell development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050764//regulation of phagocytosis;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050857//positive regulation of antigen receptor-mediated signaling pathway;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0061097//regulation of protein tyrosine kinase activity;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1903615//positive regulation of protein tyrosine phosphatase activity;GO:1903979//negative regulation of microglial cell activation;GO:1904155//DN2 thymocyte differentiation;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:2000473//positive regulation of hematopoietic stem cell migration;GO:2000648//positive regulation of stem cell proliferation;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000081248	0	0.032	0	0	0	0.011	0	4	0	0	0	1	CACNA1S	calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Signal transduction;Cancer: overview;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Circulatory system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Cardiovascular disease;Circulatory system;Nervous system;Endocrine system;Cardiovascular disease;Endocrine system;Endocrine system;Endocrine system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04924//Renin secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion"	K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857;K04857	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0031674//I band;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008331//high voltage-gated calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006936//muscle contraction;GO:0034765//regulation of ion transmembrane transport;GO:0045933//positive regulation of muscle contraction;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0071313//cellular response to caffeine	--
ENSG00000081277	1.584	1.486	1.936	2.383	2.256	3.387	175	165	158	195	211	273	PKP1	plakophilin 1 [Source:HGNC Symbol;Acc:HGNC:9023]	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0030054//cell junction;GO:0030057//desmosome;GO:0101003//ficolin-1-rich granule membrane;GO:1990124//messenger ribonucleoprotein complex	GO:0005515//protein binding;GO:0005521//lamin binding;GO:0019215//intermediate filament binding;GO:0030280//structural constituent of skin epidermis;GO:0045296//cadherin binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0045110//intermediate filament bundle assembly;GO:0098609//cell-cell adhesion;GO:1902373//negative regulation of mRNA catabolic process	--
ENSG00000081307	13.277	11.896	12.94	9.178	10.486	10.741	714.82	628	515	360	479	459	UBA5	ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0071566//UFM1 activating enzyme activity	GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0032446//protein modification by small protein conjugation;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0050905//neuromuscular process;GO:0061709//reticulophagy;GO:0071569//protein ufmylation;GO:1990592//protein K69-linked ufmylation	--
ENSG00000081320	2.47	2.438	0.966	0.575	0.559	0.38	161	211.01	56	25	35	26	STK17B	serine/threonine kinase 17b [Source:HGNC Symbol;Acc:HGNC:11396]	-	-	-	-	GO:0005634//nucleus;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:2000271//positive regulation of fibroblast apoptotic process	--
ENSG00000081377	8.095	7.803	7.615	7.279	7.956	8.53	839.27	759.32	595.14	561	708.12	648.19	CDC14B	cell division cycle 14B [Source:HGNC Symbol;Acc:HGNC:1719]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06639	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072686//mitotic spindle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006281//DNA repair;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007096//regulation of exit from mitosis;GO:0016311//dephosphorylation;GO:0032467//positive regulation of cytokinesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060271//cilium assembly;GO:1904668//positive regulation of ubiquitin protein ligase activity	--
ENSG00000081386	4.271	3.227	3.229	2.318	2.806	2.971	570	431	318	229	314	281	ZNF510	zinc finger protein 510 [Source:HGNC Symbol;Acc:HGNC:29161]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000081479	6.974	7.613	6.895	6.586	8.37	7.771	1960	2000	1464	1287	1857	1549	LRP2	LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694]	Organismal Systems;Environmental Information Processing;Organismal Systems	Endocrine system;Signal transduction;Digestive system	ko04918//Thyroid hormone synthesis;ko04340//Hedgehog signaling pathway;ko04979//Cholesterol metabolism	K06233;K06233;K06233	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031526//brush border membrane;GO:0031904//endosome lumen;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0031994//insulin-like growth factor I binding;GO:0038024//cargo receptor activity;GO:0042562//hormone binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0140318//protein transporter activity	GO:0001523//retinoid metabolic process;GO:0001822//kidney development;GO:0001843//neural tube closure;GO:0003139//secondary heart field specification;GO:0003148//outflow tract septum morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0003281//ventricular septum development;GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007399//nervous system development;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0008283//cell population proliferation;GO:0008584//male gonad development;GO:0015031//protein transport;GO:0030001//metal ion transport;GO:0030514//negative regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0035904//aorta development;GO:0042359//vitamin D metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0044321//response to leptin;GO:0045056//transcytosis;GO:0050769//positive regulation of neurogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0060068//vagina development;GO:0060976//coronary vasculature development;GO:0060982//coronary artery morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0070447//positive regulation of oligodendrocyte progenitor proliferation;GO:0071363//cellular response to growth factor stimulus;GO:0097242//amyloid-beta clearance;GO:0140058//neuron projection arborization;GO:0150104//transport across blood-brain barrier;GO:1904447//folate import across plasma membrane;GO:1905167//positive regulation of lysosomal protein catabolic process	--
ENSG00000081665	3.022	1.832	2.545	2.998	2.639	2.936	132	104.1	83	89	108	97	ZNF506	zinc finger protein 506 [Source:HGNC Symbol;Acc:HGNC:23780]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000081692	5.922	6.306	6.91	5.935	6.324	7.111	305.38	326.87	263.19	226.67	275.46	266.59	JMJD4	jumonji domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25724]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0033749//histone H3-methyl-arginine-3 demethylase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0106156//peptidyl-lysine 4-dioxygenase activity	GO:0010629//negative regulation of gene expression;GO:0018126//protein hydroxylation;GO:0043985//histone H4-R3 methylation;GO:0045905//positive regulation of translational termination;GO:0070079//histone H4-R3 demethylation	--
ENSG00000081721	5.63	6.725	6.875	5.197	6.687	8.59	129	150	112	92	131	138	DUSP12	dual specificity phosphatase 12 [Source:HGNC Symbol;Acc:HGNC:3067]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006464//cellular protein modification process;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0033133//positive regulation of glucokinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000081760	11.312	11.24	11.427	12.613	11.357	12.007	764	763	567	631	648	590	AACS	acetoacetyl-CoA synthetase [Source:HGNC Symbol;Acc:HGNC:21298]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism"	K01907;K01907;K01907	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0030729//acetoacetate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0046951//ketone body biosynthetic process	--
ENSG00000081791	29.335	30.336	30.684	34.064	31.983	28.434	1482	1645	1223	1311	1382	1206	DELE1	DAP3 binding cell death enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28969]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000081800	0	0	0	0	0	0	0	0	0	0	0	0	SLC13A1	solute carrier family 13 member 1 [Source:HGNC Symbol;Acc:HGNC:10916]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015382//sodium:sulfate symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008272//sulfate transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000081803	2.506	2.61	2.174	2.891	2.349	2.625	205	207	133	175	173	174	CADPS2	calcium dependent secretion activator 2 [Source:HGNC Symbol;Acc:HGNC:16018]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0008289//lipid binding;GO:0046872//metal ion binding	GO:0006887//exocytosis;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0045921//positive regulation of exocytosis;GO:1990504//dense core granule exocytosis	--
ENSG00000081818	0.177	0.164	0.154	0.205	0.255	0.305	14	13	9	12	17	17.52	PCDHB4	protocadherin beta 4 [Source:HGNC Symbol;Acc:HGNC:8689]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000081842	0	0.051	0	0	0.03	0.02	0	2.35	0	0	1.19	1	PCDHA6	protocadherin alpha 6 [Source:HGNC Symbol;Acc:HGNC:8672]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000081853	0	0	0	0	0.021	0.024	0	0	0	0	1.75	1.77	PCDHGA2	"protocadherin gamma subfamily A, 2 [Source:HGNC Symbol;Acc:HGNC:8700]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000081870	10.981	9.96	11.006	11.114	7.769	8.857	162	149	121	122	99	95	HSPB11	heat shock protein family B (small) member 11 [Source:HGNC Symbol;Acc:HGNC:25019]	-	-	-	-	GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001822//kidney development;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0007507//heart development;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0070986//left/right axis specification	--
ENSG00000081913	3.046	3.83	3.7	4.119	3.153	3.577	398	455	357	359	348	340	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:20610]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K16340	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0002667//regulation of T cell anergy;GO:0006470//protein dephosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0009649//entrainment of circadian clock;GO:0016311//dephosphorylation;GO:0042981//regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0046328//regulation of JNK cascade;GO:0051898//negative regulation of protein kinase B signaling;GO:1900744//regulation of p38MAPK cascade	--
ENSG00000081923	1.565	2.057	1.674	1.833	1.255	1.943	200	186	158	105	134	151	ATP8B1	ATPase phospholipid transporting 8B1 [Source:HGNC Symbol;Acc:HGNC:3706]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016604//nuclear body;GO:0032420//stereocilium;GO:0042995//cell projection;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015247//aminophospholipid flippase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090554//phosphatidylcholine floppase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140345//phosphatidylcholine flippase activity;GO:0140346//phosphatidylserine flippase activity;GO:1901612//cardiolipin binding	"GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0007030//Golgi organization;GO:0007605//sensory perception of sound;GO:0008206//bile acid metabolic process;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0015914//phospholipid transport;GO:0015917//aminophospholipid transport;GO:0021650//vestibulocochlear nerve formation;GO:0032534//regulation of microvillus assembly;GO:0034204//lipid translocation;GO:0034220//ion transmembrane transport;GO:0045176//apical protein localization;GO:0045332//phospholipid translocation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060119//inner ear receptor cell development;GO:0140331//aminophospholipid translocation;GO:1903729//regulation of plasma membrane organization;GO:2001225//regulation of chloride transport"	--
ENSG00000081985	0	0	0	0	0.021	0	0	0	0	0	2	0	IL12RB2	interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Immune system;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K05064;K05064;K05064;K05064;K05064	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019955//cytokine binding	GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032729//positive regulation of interferon-gamma production;GO:0034097//response to cytokine	--
ENSG00000082014	16.644	16.167	16.662	21.356	17.025	16.844	615.56	610.93	462.24	600.53	546	461.06	SMARCD3	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 [Source:HGNC Symbol;Acc:HGNC:11108]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11650;K11650	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016514//SWI/SNF complex;GO:0035060//brahma complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex	GO:0001221//transcription coregulator binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0140297//DNA-binding transcription factor binding	"GO:0002052//positive regulation of neuroblast proliferation;GO:0003007//heart morphogenesis;GO:0003139//secondary heart field specification;GO:0003219//cardiac right ventricle formation;GO:0003407//neural retina development;GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0042692//muscle cell differentiation;GO:0043393//regulation of protein binding;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000082068	5.629	5.644	4.521	4.348	4.078	4.698	302	303	186	178	200	172	WDR70	WD repeat domain 70 [Source:HGNC Symbol;Acc:HGNC:25495]	-	-	-	-	GO:0005634//nucleus;GO:0035861//site of double-strand break	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:1903775//regulation of DNA double-strand break processing;GO:2001173//regulation of histone H2B conserved C-terminal lysine ubiquitination	--
ENSG00000082074	0	0.01	0.042	0.054	0	0.108	0	1	3	4	0	3	FYB1	FYN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4036]	Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: bacterial	ko04015//Rap1 signaling pathway;ko05135//Yersinia infection	K17698;K17698	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0032991//protein-containing complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0044877//protein-containing complex binding	GO:0006955//immune response;GO:0007229//integrin-mediated signaling pathway;GO:0008150//biological_process;GO:0050852//T cell receptor signaling pathway;GO:0072659//protein localization to plasma membrane	--
ENSG00000082126	0	0.021	0	0.032	0	0	0	1	0	1	0	0	MPP4	membrane palmitoylated protein 4 [Source:HGNC Symbol;Acc:HGNC:13680]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21109	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0015629//actin cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0008150//biological_process;GO:0035418//protein localization to synapse	--
ENSG00000082146	44.844	44.109	42.403	43.519	45.667	55.495	1818	1774	1377	1384	1596	1668	STRADB	STE20 related adaptor beta [Source:HGNC Symbol;Acc:HGNC:13205]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04150//mTOR signaling pathway;ko04152//AMPK signaling pathway	K17532;K17532	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016235//aggresome;GO:1902554//serine/threonine protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0000902//cell morphogenesis;GO:0006468//protein phosphorylation;GO:0006611//protein export from nucleus;GO:0007049//cell cycle;GO:0007254//JNK cascade;GO:0032147//activation of protein kinase activity;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000082153	66.541	59.913	57.399	54.324	49.812	52.049	4118	3905	2785	2259	2686	2303	BZW1	basic leucine zipper and W2 domains 1 [Source:HGNC Symbol;Acc:HGNC:18380]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0006446//regulation of translational initiation	--
ENSG00000082175	0.329	1.039	0.31	0.18	0.504	0.173	89	68	60	36	77	34	PGR	progesterone receptor [Source:HGNC Symbol;Acc:HGNC:8910]	Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Cancer: overview;Cancer: specific types;Cell growth and death;Endocrine system;Endocrine system	ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko04114//Oocyte meiosis;ko04915//Estrogen signaling pathway;ko04914//Progesterone-mediated oocyte maturation	K08556;K08556;K08556;K08556;K08556	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005102//signaling receptor binding;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding"	"GO:0001542//ovulation from ovarian follicle;GO:0002070//epithelial cell maturation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030879//mammary gland development;GO:0038001//paracrine signaling;GO:0043401//steroid hormone mediated signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0050678//regulation of epithelial cell proliferation;GO:0050847//progesterone receptor signaling pathway;GO:0060748//tertiary branching involved in mammary gland duct morphogenesis"	ESR-like
ENSG00000082196	0.305	0.175	0.446	0.465	0.32	0.143	15	8	16	14	11	6	C1QTNF3	C1q and TNF related 3 [Source:HGNC Symbol;Acc:HGNC:14326]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001819//positive regulation of cytokine production;GO:0010629//negative regulation of gene expression;GO:0032715//negative regulation of interleukin-6 production;GO:0035356//cellular triglyceride homeostasis;GO:0045444//fat cell differentiation;GO:0045721//negative regulation of gluconeogenesis;GO:0050728//negative regulation of inflammatory response;GO:0070165//positive regulation of adiponectin secretion;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000082212	15.732	14.755	14.909	12.065	13.466	12.54	821	779	570	464	587	480	ME2	malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01200//Carbon metabolism;ko00620//Pyruvate metabolism	K00027;K00027	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0004470//malic enzyme activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0008948//oxaloacetate decarboxylase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051287//NAD binding	GO:0006090//pyruvate metabolic process;GO:0006108//malate metabolic process;GO:0008152//metabolic process;GO:0022900//electron transport chain;GO:1902031//regulation of NADP metabolic process	--
ENSG00000082213	7.036	7.63	6.745	6.7	7.251	8.262	511	522	300	329	425	404	C5orf22	chromosome 5 open reading frame 22 [Source:HGNC Symbol;Acc:HGNC:25639]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000082258	8.162	6.069	5.972	5.077	6.47	6.2	861	641	466	398	530	470	CCNT2	cyclin T2 [Source:HGNC Symbol;Acc:HGNC:1600]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15188	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0048471//perinuclear region of cytoplasm	GO:0001223//transcription coactivator binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity;GO:0070063//RNA polymerase binding;GO:0097322//7SK snRNA binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007519//skeletal muscle tissue development;GO:0019085//early viral transcription;GO:0019086//late viral transcription;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0043923//positive regulation by host of viral transcription;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051147//regulation of muscle cell differentiation;GO:0051301//cell division;GO:1903654//phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter;GO:1903655//phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter"	--
ENSG00000082269	3.279	2.568	2.62	1.879	2.756	2.242	369	276	217	161	228	189	FAM135A	family with sequence similarity 135 member A [Source:HGNC Symbol;Acc:HGNC:21084]	-	-	-	-	-	-	GO:0044255//cellular lipid metabolic process	--
ENSG00000082293	0.061	0.022	0.045	0.022	0.013	0.023	11	4	6	3	2	3	COL19A1	collagen type XIX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2196]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24340	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0098609//cell-cell adhesion	--
ENSG00000082397	7.71	7.542	6.238	6.345	5.582	4.181	563	532	345	244	299	231	EPB41L3	erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030673//axolemma;GO:0033270//paranode region of axon;GO:0044224//juxtaparanode region of axon	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0106006//cytoskeletal protein-membrane anchor activity	GO:0001558//regulation of cell growth;GO:0002175//protein localization to paranode region of axon;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0008150//biological_process;GO:0008360//regulation of cell shape;GO:0030865//cortical cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0030913//paranodal junction assembly;GO:0031032//actomyosin structure organization;GO:0043217//myelin maintenance;GO:0048812//neuron projection morphogenesis;GO:0071205//protein localization to juxtaparanode region of axon;GO:0072659//protein localization to plasma membrane	--
ENSG00000082438	19.888	15.074	16.682	16.172	17.935	26.206	2007	1451	1202	1237	1543	1936	COBLL1	cordon-bleu WH2 repeat protein like 1 [Source:HGNC Symbol;Acc:HGNC:23571]	-	-	-	-	GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0045296//cadherin binding	-	--
ENSG00000082458	11.366	10.759	11.196	8.693	10.331	10.052	1085	1042	790	617	841	702	DLG3	discs large MAGUK scaffold protein 3 [Source:HGNC Symbol;Acc:HGNC:2902]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K21098;K21098;K21098	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019902//phosphatase binding;GO:0031625//ubiquitin protein ligase binding	GO:0001736//establishment of planar polarity;GO:0008285//negative regulation of cell population proliferation;GO:0043113//receptor clustering;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels	--
ENSG00000082482	0.514	0.796	0.271	0.168	0.211	0.325	31	45	7	7	6	8	KCNK2	potassium two pore domain channel subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:6277]	Human Diseases;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Digestive system;Endocrine system	ko04934//Cushing syndrome;ko04971//Gastric acid secretion;ko04927//Cortisol synthesis and secretion	K04913;K04913;K04913	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0044305//calyx of Held;GO:0097449//astrocyte projection	GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0015271//outward rectifier potassium channel activity;GO:0019870//potassium channel inhibitor activity;GO:0022841//potassium ion leak channel activity	GO:0003231//cardiac ventricle development;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007613//memory;GO:0009612//response to mechanical stimulus;GO:0010942//positive regulation of cell death;GO:0030322//stabilization of membrane potential;GO:0042391//regulation of membrane potential;GO:0048678//response to axon injury;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0071456//cellular response to hypoxia;GO:0071805//potassium ion transmembrane transport;GO:0090102//cochlea development;GO:1900039//positive regulation of cellular response to hypoxia;GO:2000279//negative regulation of DNA biosynthetic process	--
ENSG00000082497	0.803	0.56	0.45	0.162	0.306	0.305	87	61	36	13	28	24	SERTAD4	SERTA domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25236]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000082512	5.005	4.119	5.236	3.703	3.832	4.197	408	320	256	202	267	221	TRAF5	TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Signal transduction;Immune system;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer	K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849;K09849	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex	GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade;GO:0048255//mRNA stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070534//protein K63-linked ubiquitination;GO:0097400//interleukin-17-mediated signaling pathway	--
ENSG00000082515	8.281	7.014	8.202	8.48	8.036	11.62	168	148	123	115	137	158	MRPL22	mitochondrial ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:14480]	Genetic Information Processing	Translation	ko03010//Ribosome	K02890	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation;GO:0042255//ribosome assembly	--
ENSG00000082516	6.495	6.435	6.233	5.203	5.206	5.885	728	725	516	432	493	480	GEMIN5	gem nuclear organelle associated protein 5 [Source:HGNC Symbol;Acc:HGNC:20043]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0032797//SMN complex;GO:0034718//SMN-Gemin2 complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies	GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0030619//U1 snRNA binding;GO:0030621//U4 snRNA binding;GO:0030622//U4atac snRNA binding;GO:0043022//ribosome binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006412//translation;GO:0006417//regulation of translation;GO:0008380//RNA splicing;GO:0065003//protein-containing complex assembly"	--
ENSG00000082556	0	0.01	0.013	0	0	0	0	1	1	0	0	0	OPRK1	opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HGNC:8154]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04214	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0004930//G protein-coupled receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0033612//receptor serine/threonine kinase binding;GO:0038048//dynorphin receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007600//sensory perception;GO:0007610//behavior;GO:0007626//locomotory behavior;GO:0009314//response to radiation;GO:0019233//sensory perception of pain;GO:0031635//adenylate cyclase-inhibiting opioid receptor signaling pathway;GO:0032868//response to insulin;GO:0033603//positive regulation of dopamine secretion;GO:0033685//negative regulation of luteinizing hormone secretion;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0040017//positive regulation of locomotion;GO:0042220//response to cocaine;GO:0042711//maternal behavior;GO:0042755//eating behavior;GO:0043278//response to morphine;GO:0043627//response to estrogen;GO:0044849//estrous cycle;GO:0045471//response to ethanol;GO:0046877//regulation of saliva secretion;GO:0048148//behavioral response to cocaine;GO:0050951//sensory perception of temperature stimulus;GO:0051607//defense response to virus;GO:0051930//regulation of sensory perception of pain;GO:0071222//cellular response to lipopolysaccharide;GO:0071333//cellular response to glucose stimulus;GO:1900745//positive regulation of p38MAPK cascade;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903937//response to acrylamide;GO:1904000//positive regulation of eating behavior;GO:1990708//conditioned place preference	--
ENSG00000082641	160.994	171.465	179.052	172.275	189.883	176.705	13235	14473	10905	10637	12778	10176	NFE2L1	"nuclear factor, erythroid 2 like 1 [Source:HGNC Symbol;Acc:HGNC:7781]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006783//heme biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0034599//cellular response to oxidative stress;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000082684	0.524	0.364	0.194	0.084	0.114	0.052	28	27	14	2	9	3	SEMA5B	semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06841	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048675//axon extension;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050908//detection of light stimulus involved in visual perception;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0097485//neuron projection guidance;GO:1990138//neuron projection extension	--
ENSG00000082701	12.154	11.367	12.196	10.785	9.991	11.987	1472	1409	1132	897	1082	1037	GSK3B	glycogen synthase kinase 3 beta [Source:HGNC Symbol;Acc:HGNC:4617]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Nervous system;Cell growth and death;Endocrine system;Nervous system;Endocrine system;Endocrine and metabolic disease;Immune system;Endocrine system;Cancer: specific types;Immune system;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Endocrine system;Cancer: specific types;Cancer: specific types;Signal transduction	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05020//Prion disease;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04728//Dopaminergic synapse;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04657//IL-17 signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04917//Prolactin signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko04340//Hedgehog signaling pathway"	K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083;K03083	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030877//beta-catenin destruction complex;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:1990909//Wnt signalosome	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008013//beta-catenin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0034452//dynactin binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0051059//NF-kappaB binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106310//protein serine kinase activity	GO:0001837//epithelial to mesenchymal transition;GO:0001954//positive regulation of cell-matrix adhesion;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006468//protein phosphorylation;GO:0006983//ER overload response;GO:0007165//signal transduction;GO:0007212//dopamine receptor signaling pathway;GO:0007399//nervous system development;GO:0007623//circadian rhythm;GO:0008286//insulin receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010822//positive regulation of mitochondrion organization;GO:0010975//regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019082//viral protein processing;GO:0021766//hippocampus development;GO:0030010//establishment of cell polarity;GO:0030011//maintenance of cell polarity;GO:0030154//cell differentiation;GO:0030516//regulation of axon extension;GO:0031175//neuron projection development;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032886//regulation of microtubule-based process;GO:0035556//intracellular signal transduction;GO:0036016//cellular response to interleukin-3;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043547//positive regulation of GTPase activity;GO:0045597//positive regulation of cell differentiation;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0045724//positive regulation of cilium assembly;GO:0045732//positive regulation of protein catabolic process;GO:0046777//protein autophosphorylation;GO:0046825//regulation of protein export from nucleus;GO:0046827//positive regulation of protein export from nucleus;GO:0048511//rhythmic process;GO:0048814//regulation of dendrite morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051093//negative regulation of developmental process;GO:0051128//regulation of cellular component organization;GO:0060079//excitatory postsynaptic potential;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071109//superior temporal gyrus development;GO:0071300//cellular response to retinoic acid;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0106027//neuron projection organization;GO:0150101//regulation of microtubule anchoring at centrosome;GO:1900034//regulation of cellular response to heat;GO:1900181//negative regulation of protein localization to nucleus;GO:1900271//regulation of long-term synaptic potentiation;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1901215//negative regulation of neuron death;GO:1901216//positive regulation of neuron death;GO:1901984//negative regulation of protein acetylation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903566//positive regulation of protein localization to cilium;GO:1904339//negative regulation of dopaminergic neuron differentiation;GO:1904646//cellular response to amyloid-beta;GO:1904781//positive regulation of protein localization to centrosome;GO:1904886//beta-catenin destruction complex disassembly;GO:1905240//negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation;GO:2000077//negative regulation of type B pancreatic cell development;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:2000740//negative regulation of mesenchymal stem cell differentiation	--
ENSG00000082781	53.648	59.985	47.394	40.199	47.63	41.387	4394	4753	2784	2481	3194	2322	ITGB5	integrin subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:6160]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06588;K06588;K06588;K06588;K06588;K06588;K06588;K06588;K06588;K06588	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034684//integrin alphav-beta5 complex;GO:0043235//receptor complex;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0035987//endodermal cell differentiation;GO:0043149//stress fiber assembly;GO:0046718//viral entry into host cell;GO:0090136//epithelial cell-cell adhesion	--
ENSG00000082805	12.002	11.197	8.187	6.457	8.86	5.748	1752	1730	1109	811	1123	746	ERC1	ELKS/RAB6-interacting/CAST family member 1 [Source:HGNC Symbol;Acc:HGNC:17072]	Environmental Information Processing	Signal transduction	ko04064//NF-kappa B signaling pathway	K16072	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008385//IkappaB kinase complex;GO:0016020//membrane;GO:0030054//cell junction;GO:0036064//ciliary basal body;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048788//cytoskeleton of presynaptic active zone;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding;GO:0098882//structural constituent of presynaptic active zone	"GO:0006355//regulation of transcription, DNA-templated;GO:0007252//I-kappaB phosphorylation;GO:0007274//neuromuscular synaptic transmission;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0048167//regulation of synaptic plasticity;GO:0048790//maintenance of presynaptic active zone structure;GO:0051092//positive regulation of NF-kappaB transcription factor activity"	--
ENSG00000082898	42.145	32.898	31.568	24.828	28.058	29.372	3606	2869	1995	1591	2114	1824	XPO1	exportin 1 [Source:HGNC Symbol;Acc:HGNC:12825]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Infectious disease: viral;Translation;Translation	ko05166//Human T-cell leukemia virus 1 infection;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03008//Ribosome biogenesis in eukaryotes	K14290;K14290;K14290;K14290	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005642//annulate lamellae;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000054//ribosomal subunit export from nucleus;GO:0000055//ribosomal large subunit export from nucleus;GO:0000056//ribosomal small subunit export from nucleus;GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0006913//nucleocytoplasmic transport;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033036//macromolecule localization;GO:0034504//protein localization to nucleus;GO:0042176//regulation of protein catabolic process;GO:0042254//ribosome biogenesis;GO:0046825//regulation of protein export from nucleus;GO:0051028//mRNA transport;GO:0071702//organic substance transport	--
ENSG00000082996	69.816	72.207	72.059	68.273	62.725	76.35	2952	2864	2115	2054	2177	2408	RNF13	ring finger protein 13 [Source:HGNC Symbol;Acc:HGNC:10057]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0070304//positive regulation of stress-activated protein kinase signaling cascade	--
ENSG00000083067	308.065	291.469	353.454	282.528	279.944	342.723	10917	9918	8611	6954	8188	8379	TRPM3	transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0016048//detection of temperature stimulus;GO:0034220//ion transmembrane transport;GO:0050951//sensory perception of temperature stimulus;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000083093	3.633	3.418	3.476	2.426	4	3.449	289	249	188	149	231	185	PALB2	partner and localizer of BRCA2 [Source:HGNC Symbol;Acc:HGNC:26144]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K10897;K10897	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:1990391//DNA repair complex	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001833//inner cell mass cell proliferation;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007498//mesoderm development;GO:0009887//animal organ morphogenesis;GO:0035264//multicellular organism growth;GO:0036342//post-anal tail morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0048568//embryonic organ development	--
ENSG00000083097	7.917	4.982	3.967	2.428	3.622	4.668	680.16	441.06	305.21	221.96	343.29	354.64	DOP1A	DOP1 leucine zipper like protein A [Source:HGNC Symbol;Acc:HGNC:21194]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane	-	GO:0006895//Golgi to endosome transport;GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport	--
ENSG00000083099	10.304	13.976	12.333	10.543	9.702	12.232	730.43	722.82	487.65	411.34	463.8	509.54	LYRM2	LYR motif containing 2 [Source:HGNC Symbol;Acc:HGNC:25229]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000083123	12.854	13.099	11.728	10.896	12.074	12.642	746	732	504	484	565	502	BCKDHB	branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism"	K00167;K00167;K00167	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex	GO:0003824//catalytic activity;GO:0003863//3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0044877//protein-containing complex binding	GO:0006629//lipid metabolic process;GO:0007584//response to nutrient;GO:0009083//branched-chain amino acid catabolic process;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP	--
ENSG00000083168	11.534	9.679	10.528	7.294	8.871	7.837	1882	1628	1172	904	1162	964	KAT6A	lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11305	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0010484//H3 histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006323//DNA packaging;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0006473//protein acetylation;GO:0010628//positive regulation of gene expression;GO:0016573//histone acetylation;GO:0030099//myeloid cell differentiation;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development;GO:0050793//regulation of developmental process;GO:0090398//cellular senescence;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1903706//regulation of hemopoiesis"	--
ENSG00000083223	3.266	2.106	1.981	1.601	1.856	1.664	362	242	167	137	179	140	TUT7	terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0050265//RNA uridylyltransferase activity;GO:0070569//uridylyltransferase activity	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001556//oocyte maturation;GO:0010526//negative regulation of transposition, RNA-mediated;GO:0010586//miRNA metabolic process;GO:0031054//pre-miRNA processing;GO:0031123//RNA 3'-end processing;GO:0071076//RNA 3' uridylation;GO:1990074//polyuridylation-dependent mRNA catabolic process"	--
ENSG00000083290	15.655	13.336	14.683	14.887	12.643	13.672	1421	1294	1027	912	1067	995	ULK2	unc-51 like autophagy activating kinase 2 [Source:HGNC Symbol;Acc:HGNC:13480]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04136//Autophagy - other	K08269;K08269;K08269;K08269;K08269;K08269;K08269;K08269	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034045//phagophore assembly site membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0010508//positive regulation of autophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034727//piecemeal microautophagy of the nucleus;GO:0042594//response to starvation;GO:0044805//late nucleophagy;GO:0046777//protein autophosphorylation;GO:0048671//negative regulation of collateral sprouting;GO:0048675//axon extension;GO:0061709//reticulophagy	--
ENSG00000083307	0	0	0	0	0.022	0	0	0	0	0	2	0	GRHL2	grainyhead like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:2799]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005911//cell-cell junction;GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001161//intronic transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding"	"GO:0001701//in utero embryonic development;GO:0001843//neural tube closure;GO:0003208//cardiac ventricle morphogenesis;GO:0003382//epithelial cell morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007420//brain development;GO:0008283//cell population proliferation;GO:0008544//epidermis development;GO:0010468//regulation of gene expression;GO:0021915//neural tube development;GO:0030323//respiratory tube development;GO:0034329//cell junction assembly;GO:0035264//multicellular organism growth;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0044030//regulation of DNA methylation;GO:0045617//negative regulation of keratinocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0051973//positive regulation of telomerase activity;GO:0060324//face development;GO:0060463//lung lobe morphogenesis;GO:0060487//lung epithelial cell differentiation;GO:0060672//epithelial cell morphogenesis involved in placental branching;GO:0061713//anterior neural tube closure;GO:0070830//bicellular tight junction assembly;GO:0090132//epithelium migration"	CP2
ENSG00000083312	34.61	29.916	28.164	22.065	25.892	28.442	4819	3784	2833	2195	2727	2805	TNPO1	transportin 1 [Source:HGNC Symbol;Acc:HGNC:6401]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K18752	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0031267//small GTPase binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000083444	105.486	112.797	115.218	95.853	98.098	96.85	6383	6849	5188	4307	4995	4255	PLOD1	"procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:9081]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K00473;K00473	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0070062//extracellular exosome;GO:1902494//catalytic complex	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001666//response to hypoxia;GO:0008544//epidermis development;GO:0017185//peptidyl-lysine hydroxylation	--
ENSG00000083454	0	0.056	0	0.101	0.035	0.106	0	1	0	2	1	2.97	P2RX5	purinergic receptor P2X 5 [Source:HGNC Symbol;Acc:HGNC:8536]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K05219;K05219	GO:0005639//integral component of nuclear inner membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098794//postsynapse	GO:0000166//nucleotide binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005216//ion channel activity;GO:0005524//ATP binding;GO:0015267//channel activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0033198//response to ATP;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0050850//positive regulation of calcium-mediated signaling;GO:0060079//excitatory postsynaptic potential;GO:0065008//regulation of biological quality;GO:0098655//cation transmembrane transport	--
ENSG00000083457	0.52	0.277	0.395	0.462	0.255	0.732	41	22	23	27	17	42	ITGAE	integrin subunit alpha E [Source:HGNC Symbol;Acc:HGNC:6147]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K06524	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0098609//cell-cell adhesion	--
ENSG00000083520	7.894	6.587	5.891	4.689	5.832	6.147	764.78	604.27	413.06	333	458.46	402.19	DIS3	"DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:20604]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12585	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004527//exonuclease activity;GO:0004540//ribonuclease activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0010467//gene expression;GO:0016075//rRNA catabolic process;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0050790//regulation of catalytic activity;GO:0071034//CUT catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000083535	2.411	2.165	1.813	1.014	2.276	2.246	154	139	85	48	100	104	PIBF1	progesterone immunomodulatory binding factor 1 [Source:HGNC Symbol;Acc:HGNC:23352]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005136//interleukin-4 receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0007080//mitotic metaphase plate congression;GO:0031393//negative regulation of prostaglandin biosynthetic process;GO:0032695//negative regulation of interleukin-12 production;GO:0032733//positive regulation of interleukin-10 production;GO:0032815//negative regulation of natural killer cell activation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042976//activation of Janus kinase activity;GO:0060271//cilium assembly;GO:0071539//protein localization to centrosome;GO:0090307//mitotic spindle assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000083544	7.651	6.387	6.141	5.046	5.928	6.739	409	337	237	196	261	244	TDRD3	tudor domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20612]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0140225//DNA topoisomerase III-beta-TDRD3 complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006265//DNA topological change;GO:0006325//chromatin organization;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000083635	2.535	2.178	2.251	2.02	2.001	2.19	183	158	120	108	122	115	NUFIP1	nuclear FMR1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8057]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005726//perichromatin fibrils;GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex;GO:0016363//nuclear matrix;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0070761//pre-snoRNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding	GO:0000492//box C/D snoRNP assembly;GO:0006396//RNA processing;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000083642	6.202	5.651	3.672	2.5	4.211	4.215	573	444	240	160	235	210	PDS5B	PDS5 cohesin associated factor B [Source:HGNC Symbol;Acc:HGNC:20418]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0042127//regulation of cell population proliferation;GO:0051301//cell division	--
ENSG00000083720	28.637	28.003	24.728	20.489	21.675	21.437	1685	1688	1127	1027	1178	941	OXCT1	3-oxoacid CoA-transferase 1 [Source:HGNC Symbol;Acc:HGNC:8527]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism"	K01027;K01027;K01027	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0008260//3-oxoacid CoA-transferase activity;GO:0008410//CoA-transferase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0007420//brain development;GO:0007507//heart development;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0014823//response to activity;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042182//ketone catabolic process;GO:0042594//response to starvation;GO:0045471//response to ethanol;GO:0046950//cellular ketone body metabolic process;GO:0046952//ketone body catabolic process;GO:0060612//adipose tissue development	--
ENSG00000083750	14.071	14.712	14.656	15.787	14.032	13.264	545	558	412	409	452	374	RRAGB	Ras related GTP binding B [Source:HGNC Symbol;Acc:HGNC:19901]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: bacterial;Signal transduction;Transport and catabolism	ko05131//Shigellosis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K16185;K16185;K16185	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:1990131//Gtr1-Gtr2 GTPase complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0032561//guanyl ribonucleotide binding;GO:0051020//GTPase binding	GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0032006//regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0034613//cellular protein localization;GO:0071230//cellular response to amino acid stimulus;GO:1904263//positive regulation of TORC1 signaling;GO:1990253//cellular response to leucine starvation	--
ENSG00000083782	0.065	0.032	0	0.264	0.077	0.134	2	1	0	6	2	3	EPYC	epiphycan [Source:HGNC Symbol;Acc:HGNC:3053]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding	GO:0007565//female pregnancy;GO:0007605//sensory perception of sound;GO:0060348//bone development;GO:0061975//articular cartilage development	--
ENSG00000083799	21.465	19.343	16.527	18.183	16.943	20.031	2026	1809	1248	1098	1290	1294	CYLD	CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]	Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell growth and death;Development and regeneration;Immune system;Immune system	ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04380//Osteoclast differentiation;ko04625//C-type lectin receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway	K08601;K08601;K08601;K08601;K08601	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0097542//ciliary tip	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070064//proline-rich region binding	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016579//protein deubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response;GO:0046329//negative regulation of JNK cascade;GO:0050727//regulation of inflammatory response;GO:0050728//negative regulation of inflammatory response;GO:0060544//regulation of necroptotic process;GO:0070266//necroptotic process;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0070536//protein K63-linked deubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1902017//regulation of cilium assembly;GO:1903753//negative regulation of p38MAPK cascade;GO:1990108//protein linear deubiquitination;GO:2000493//negative regulation of interleukin-18-mediated signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001242//regulation of intrinsic apoptotic signaling pathway	--
ENSG00000083807	6.179	4.083	4.228	7.332	4.343	4.551	89.72	58.24	44.07	76.83	54.06	45.27	SLC27A5	solute carrier family 27 member 5 [Source:HGNC Symbol;Acc:HGNC:10999]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Endocrine and metabolic disease;Digestive system;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko04931//Insulin resistance;ko04976//Bile secretion;ko03320//PPAR signaling pathway;ko00120//Primary bile acid biosynthesis	K08748;K08748;K08748;K08748;K08748	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015245//fatty acid transmembrane transporter activity;GO:0016491//oxidoreductase activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0044877//protein-containing complex binding;GO:0047747//cholate-CoA ligase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006642//triglyceride mobilization;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0015721//bile acid and bile salt transport;GO:0015908//fatty acid transport;GO:0015911//long-chain fatty acid import across plasma membrane;GO:0046951//ketone body biosynthetic process	--
ENSG00000083812	2.676	3.303	2.944	3.064	3.818	3.244	280.57	313.14	228.46	195.95	282.66	217.66	ZNF324	zinc finger protein 324 [Source:HGNC Symbol;Acc:HGNC:14096]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation"	zf-C2H2
ENSG00000083814	5.06	5.268	5.595	5.699	5.962	5.449	240	266	205	216	234	198	ZNF671	zinc finger protein 671 [Source:HGNC Symbol;Acc:HGNC:26279]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000083817	2.728	3.298	3.617	4.066	3.61	3.02	144	175	141	159	161	116	ZNF416	zinc finger protein 416 [Source:HGNC Symbol;Acc:HGNC:20645]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000083828	2.664	2.866	3.022	3.18	2.766	3.725	112	125	89	83	82	96	ZNF586	zinc finger protein 586 [Source:HGNC Symbol;Acc:HGNC:25949]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000083838	5.659	5.991	5.631	6.55	6.847	6.138	256.29	276.14	193.34	195.65	256.38	212.06	ZNF446	zinc finger protein 446 [Source:HGNC Symbol;Acc:HGNC:21036]	-	-	-	-	GO:0000785//chromatin;GO:0005615//extracellular space;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000083844	8.087	3.971	4.296	4.846	4.463	4.515	621	628	488	428	478	462	ZNF264	zinc finger protein 264 [Source:HGNC Symbol;Acc:HGNC:13057]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000083845	315.392	337.51	344.67	386.76	325.02	276.886	4857	5214	3920	4410	4222	3100	RPS5	ribosomal protein S5 [Source:HGNC Symbol;Acc:HGNC:10426]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02989;K02989	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0000028//ribosomal small subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006450//regulation of translational fidelity	--
ENSG00000083857	59.855	56.584	54.379	46.99	51.733	53.392	13667	12132	8984	7379	9663	8678	FAT1	FAT atypical cadherin 1 [Source:HGNC Symbol;Acc:HGNC:3595]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0002088//lens development in camera-type eye;GO:0003382//epithelial cell morphogenesis;GO:0003412//establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007163//establishment or maintenance of cell polarity;GO:0007267//cell-cell signaling;GO:0009653//anatomical structure morphogenesis;GO:0016477//cell migration;GO:0043010//camera-type eye development;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0048593//camera-type eye morphogenesis;GO:0098609//cell-cell adhesion	--
ENSG00000083896	17.222	16.672	15.443	12.456	13.814	14.92	1104	1103	738	607	773	694	YTHDC1	YTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30626]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:1990247//N6-methyladenosine-containing RNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0010608//posttranscriptional regulation of gene expression;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0048160//primary follicle stage;GO:0110104//mRNA alternative polyadenylation"	--
ENSG00000083937	21.742	19.152	19.059	17.03	15.758	20.245	1151	1023	757	663	716	764	CHMP2B	charged multivesicular body protein 2B [Source:HGNC Symbol;Acc:HGNC:24537]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04144//Endocytosis;ko04217//Necroptosis	K12192;K12192;K12192;K12192	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0045296//cadherin binding	GO:0001778//plasma membrane repair;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007032//endosome organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016032//viral process;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0031468//nuclear membrane reassembly;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0050890//cognition;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0070050//neuron cellular homeostasis;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:0140014//mitotic nuclear division;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904903//ESCRT III complex disassembly	--
ENSG00000084070	7.9	7.541	7.842	8.755	8.486	8.026	476	456	349	385	432	351	SMAP2	small ArfGAP2 [Source:HGNC Symbol;Acc:HGNC:25082]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12486	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000084072	16.462	17.175	18.245	21.645	18.815	24.678	518	538	425	474	490	533	PPIE	peptidylprolyl isomerase E [Source:HGNC Symbol;Acc:HGNC:9258]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K09564	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0034774//secretory granule lumen;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006457//protein folding;GO:0008380//RNA splicing;GO:0045070//positive regulation of viral genome replication"	--
ENSG00000084073	46.657	42.95	42.217	37.661	37.687	43.197	2925	2729	1964	1748	2011	1983	ZMPSTE24	zinc metallopeptidase STE24 [Source:HGNC Symbol;Acc:HGNC:12877]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K06013	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003690//double-stranded DNA binding;GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0001889//liver development;GO:0001942//hair follicle development;GO:0003007//heart morphogenesis;GO:0003229//ventricular cardiac muscle tissue development;GO:0003231//cardiac ventricle development;GO:0003417//growth plate cartilage development;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0006925//inflammatory cell apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006997//nucleus organization;GO:0006998//nuclear envelope organization;GO:0007346//regulation of mitotic cell cycle;GO:0007628//adult walking behavior;GO:0008016//regulation of heart contraction;GO:0008340//determination of adult lifespan;GO:0008360//regulation of cell shape;GO:0008544//epidermis development;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010906//regulation of glucose metabolic process;GO:0016485//protein processing;GO:0019216//regulation of lipid metabolic process;GO:0030282//bone mineralization;GO:0030327//prenylated protein catabolic process;GO:0030500//regulation of bone mineralization;GO:0032006//regulation of TOR signaling;GO:0032350//regulation of hormone metabolic process;GO:0035264//multicellular organism growth;GO:0040014//regulation of multicellular organism growth;GO:0043007//maintenance of rDNA;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043969//histone H2B acetylation;GO:0043979//histone H2B-K5 acetylation;GO:0044029//hypomethylation of CpG island;GO:0044030//regulation of DNA methylation;GO:0044255//cellular lipid metabolic process;GO:0048145//regulation of fibroblast proliferation;GO:0048538//thymus development;GO:0050688//regulation of defense response to virus;GO:0050905//neuromuscular process;GO:0051276//chromosome organization;GO:0055013//cardiac muscle cell development;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060993//kidney morphogenesis;GO:0061337//cardiac conduction;GO:0061762//CAMKK-AMPK signaling cascade;GO:0070302//regulation of stress-activated protein kinase signaling cascade;GO:0071480//cellular response to gamma radiation;GO:0071586//CAAX-box protein processing;GO:0072423//response to DNA damage checkpoint signaling;GO:0090239//regulation of histone H4 acetylation;GO:1903025//regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1903463//regulation of mitotic cell cycle DNA replication;GO:1903522//regulation of blood circulation;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1990036//calcium ion import into sarcoplasmic reticulum;GO:1990164//histone H2A phosphorylation;GO:2000618//regulation of histone H4-K16 acetylation;GO:2000730//regulation of termination of RNA polymerase I transcription;GO:2000772//regulation of cellular senescence"	--
ENSG00000084090	94.302	94.089	88.078	80.709	80.599	86.19	6571	6591	4530	4138	4710	4358	STARD7	StAR related lipid transfer domain containing 7 [Source:HGNC Symbol;Acc:HGNC:18063]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane	GO:0005515//protein binding;GO:0008289//lipid binding	-	--
ENSG00000084092	11.977	12.845	11.331	10.241	12.169	13.294	551	594	385	349	473	445	NOA1	nitric oxide associated 1 [Source:HGNC Symbol;Acc:HGNC:28473]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006915//apoptotic process;GO:0010941//regulation of cell death;GO:0032543//mitochondrial translation;GO:0043457//regulation of cellular respiration	--
ENSG00000084093	6.228	5.416	4.572	3.304	3.721	4.689	852	738	499	371	477	457	REST	RE1 silencing transcription factor [Source:HGNC Symbol;Acc:HGNC:9966]	Human Diseases;Cellular Processes	Neurodegenerative disease;Cellular community - eukaryotes	ko05016//Huntington disease;ko04550//Signaling pathways regulating pluripotency of stem cells	K09222;K09222	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0017053//transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001666//response to hypoxia;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002931//response to ischemia;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0035019//somatic stem cell population maintenance;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043922//negative regulation by host of viral transcription;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045667//regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0046676//negative regulation of insulin secretion;GO:0050768//negative regulation of neurogenesis;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0070933//histone H4 deacetylation;GO:0071257//cellular response to electrical stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0097150//neuronal stem cell population maintenance;GO:0099563//modification of synaptic structure;GO:1902459//positive regulation of stem cell population maintenance;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1903203//regulation of oxidative stress-induced neuron death;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903223//positive regulation of oxidative stress-induced neuron death;GO:2000065//negative regulation of cortisol biosynthetic process;GO:2000706//negative regulation of dense core granule biogenesis;GO:2000740//negative regulation of mesenchymal stem cell differentiation;GO:2000798//negative regulation of amniotic stem cell differentiation"	zf-C2H2
ENSG00000084110	0	0	0.052	0	0.015	0	0	0	3	0	1	0	HAL	histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K01745;K01745	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004397//histidine ammonia-lyase activity;GO:0016829//lyase activity;GO:0016841//ammonia-lyase activity	GO:0006547//histidine metabolic process;GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate	--
ENSG00000084112	15.59	13.46	14.741	14.053	15.676	17.606	2575	2411	1828	1793	2203	2001	SSH1	slingshot protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30579]	Cellular Processes;Organismal Systems	Cell motility;Development and regeneration	ko04810//Regulation of actin cytoskeleton;ko04360//Axon guidance	K05766;K05766	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0042995//cell projection	GO:0003779//actin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000902//cell morphogenesis;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030837//negative regulation of actin filament polymerization;GO:0032268//regulation of cellular protein metabolic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0071318//cellular response to ATP	--
ENSG00000084207	1311.489	1326.862	1333.713	1397.29	1270.041	1287.725	20150	20491	15132	15899	16484	14394	GSTP1	glutathione S-transferase pi 1 [Source:HGNC Symbol;Acc:HGNC:4638]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: specific types;Cardiovascular disease;Cancer: specific types;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko05215//Prostate cancer;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K23790;K23790;K23790;K23790;K23790;K23790;K23790;K23790;K23790;K23790;K23790	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031982//vesicle;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0097057//TRAF2-GSTP1 complex;GO:1904813//ficolin-1-rich granule lumen	GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0016740//transferase activity;GO:0019207//kinase regulator activity;GO:0035730//S-nitrosoglutathione binding;GO:0035731//dinitrosyl-iron complex binding;GO:0070026//nitric oxide binding	GO:0000302//response to reactive oxygen species;GO:0002674//negative regulation of acute inflammatory response;GO:0006469//negative regulation of protein kinase activity;GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007417//central nervous system development;GO:0009890//negative regulation of biosynthetic process;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032872//regulation of stress-activated MAPK cascade;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0032930//positive regulation of superoxide anion generation;GO:0035726//common myeloid progenitor cell proliferation;GO:0035732//nitric oxide storage;GO:0043066//negative regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0043508//negative regulation of JUN kinase activity;GO:0043651//linoleic acid metabolic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0051122//hepoxilin biosynthetic process;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070664//negative regulation of leukocyte proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0098869//cellular oxidant detoxification;GO:1901687//glutathione derivative biosynthetic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000084234	339.104	340.732	344.951	392.436	411.027	426.097	22370	22560	16865	19335	23117	20526	APLP2	amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598]	-	-	-	-	GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000084444	2.663	2.281	2.827	3.053	2.847	3.91	251	224	204	221	232	278	FAM234B	family with sequence similarity 234 member B [Source:HGNC Symbol;Acc:HGNC:29288]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000084453	3.231	2.338	2.709	1.77	1.793	2.472	189	131	101	71	81	91	SLCO1A2	solute carrier organic anion transporter family member 1A2 [Source:HGNC Symbol;Acc:HGNC:10956]	Organismal Systems	Digestive system	ko04976//Bile secretion	K03460	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000084463	18.775	18.491	17.099	15.103	16.356	15.26	1784	1766	1200	1063	1313	1055	WBP11	WW domain binding protein 11 [Source:HGNC Symbol;Acc:HGNC:16461]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12866	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0050699//WW domain binding	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000084623	76.639	87.459	78.498	77.621	76.72	74.927	2015	2283	1568	1521	1670	1522	EIF3I	eukaryotic translation initiation factor 3 subunit I [Source:HGNC Symbol;Acc:HGNC:3272]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0070062//extracellular exosome;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000084628	0.066	0.158	0.134	0.067	0.156	0.045	4	6	6	3	8	2	NKAIN1	sodium/potassium transporting ATPase interacting 1 [Source:HGNC Symbol;Acc:HGNC:25743]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0051117//ATPase binding	GO:0002028//regulation of sodium ion transport	--
ENSG00000084636	11.414	12.006	11.724	10.965	12.882	11.942	1072	1229	724	786	1013	808	COL16A1	collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24339	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005588//collagen type V trimer;GO:0005597//collagen type XVI trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007565//female pregnancy;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0033622//integrin activation;GO:0033627//cell adhesion mediated by integrin;GO:0051894//positive regulation of focal adhesion assembly;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000084652	17.27	20.006	18.954	15.133	17.674	18.334	1758	2045	1426	1142	1523	1362	TXLNA	taxilin alpha [Source:HGNC Symbol;Acc:HGNC:30685]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006887//exocytosis;GO:0042113//B cell activation	--
ENSG00000084674	0.018	0.003	0	0	0.017	0.021	2	1	0	0	3	1	APOB	apolipoprotein B [Source:HGNC Symbol;Acc:HGNC:603]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cardiovascular disease;Digestive system;Digestive system;Digestive system	ko05417//Lipid and atherosclerosis;ko04979//Cholesterol metabolism;ko04975//Fat digestion and absorption;ko04977//Vitamin digestion and absorption	K14462;K14462;K14462;K14462	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012506//vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031904//endosome lumen;GO:0031983//vesicle lumen;GO:0034359//mature chylomicron;GO:0034360//chylomicron remnant;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0043025//neuronal cell body;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0070971//endoplasmic reticulum exit site;GO:0071682//endocytic vesicle lumen	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0035473//lipase binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0120020//cholesterol transfer activity	GO:0001701//in utero embryonic development;GO:0006629//lipid metabolic process;GO:0006642//triglyceride mobilization;GO:0006869//lipid transport;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009566//fertilization;GO:0009615//response to virus;GO:0009743//response to carbohydrate;GO:0009791//post-embryonic development;GO:0010033//response to organic substance;GO:0010269//response to selenium ion;GO:0010628//positive regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010884//positive regulation of lipid storage;GO:0010886//positive regulation of cholesterol storage;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0030301//cholesterol transport;GO:0030317//flagellated sperm motility;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0033344//cholesterol efflux;GO:0034374//low-density lipoprotein particle remodeling;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034383//low-density lipoprotein particle clearance;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042159//lipoprotein catabolic process;GO:0042632//cholesterol homeostasis;GO:0042953//lipoprotein transport;GO:0045540//regulation of cholesterol biosynthetic process;GO:0048844//artery morphogenesis;GO:0071356//cellular response to tumor necrosis factor;GO:0071379//cellular response to prostaglandin stimulus;GO:0120009//intermembrane lipid transfer	--
ENSG00000084676	12.403	10.963	10.705	9.17	10.293	10.956	1686	1536	1064	952	1199	1098	NCOA1	nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:7668]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Cancer: specific types;Endocrine system;Endocrine system	ko05200//Pathways in cancer;ko05224//Breast cancer;ko04915//Estrogen signaling pathway;ko04919//Thyroid hormone signaling pathway	K09101;K09101;K09101;K09101	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016922//nuclear receptor binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0019899//enzyme binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0046983//protein dimerization activity;GO:0047485//protein N-terminus binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000435//positive regulation of transcription from RNA polymerase II promoter by galactose;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0032870//cellular response to hormone stimulus;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060713//labyrinthine layer morphogenesis;GO:1900076//regulation of cellular response to insulin stimulus;GO:1904017//cellular response to Thyroglobulin triiodothyronine;GO:1904179//positive regulation of adipose tissue development"	bHLH
ENSG00000084693	21.954	22.528	22.735	27.016	24.437	23.496	1154	1138.15	919	1008.08	1094	953	AGBL5	AGBL carboxypeptidase 5 [Source:HGNC Symbol;Acc:HGNC:26147]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0035608//protein deglutamylation;GO:0035609//C-terminal protein deglutamylation;GO:0035610//protein side chain deglutamylation;GO:0035611//protein branching point deglutamylation;GO:0051607//defense response to virus	--
ENSG00000084710	19.617	19.52	22.074	21.438	25.025	23.846	3041	3040	2530	2463	3280	2692	EFR3B	EFR3 homolog B [Source:HGNC Symbol;Acc:HGNC:29155]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding	GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000084731	7.175	7.484	7.256	6.445	6.943	6.413	795	824	590	520	632	517	KIF3C	kinesin family member 3C [Source:HGNC Symbol;Acc:HGNC:6321]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement;GO:0072384//organelle transport along microtubule	--
ENSG00000084733	19.997	18.669	19.963	17.071	16.105	17.137	1477	1386	1089	934	1005	921	RAB10	"RAB10, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9759]"	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04152//AMPK signaling pathway	K07903;K07903	GO:0000139//Golgi membrane;GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032593//insulin-responsive compartment;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070382//exocytic vesicle;GO:0071782//endoplasmic reticulum tubular network	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0031489//myosin V binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0007409//axonogenesis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0017157//regulation of exocytosis;GO:0019882//antigen processing and presentation;GO:0030859//polarized epithelial cell differentiation;GO:0032869//cellular response to insulin stimulus;GO:0043001//Golgi to plasma membrane protein transport;GO:0045055//regulated exocytosis;GO:0045200//establishment of neuroblast polarity;GO:0071786//endoplasmic reticulum tubular network organization;GO:0072659//protein localization to plasma membrane;GO:0090150//establishment of protein localization to membrane;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:0098609//cell-cell adhesion;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000084734	0.069	0	0	0	0	0	1	0	0	0	0	0	GCKR	glucokinase regulator [Source:HGNC Symbol;Acc:HGNC:4196]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0030246//carbohydrate binding;GO:0070095//fructose-6-phosphate binding;GO:0097367//carbohydrate derivative binding	GO:0005975//carbohydrate metabolic process;GO:0006606//protein import into nucleus;GO:0009750//response to fructose;GO:0016310//phosphorylation;GO:0033132//negative regulation of glucokinase activity;GO:0042593//glucose homeostasis;GO:0046415//urate metabolic process;GO:0070328//triglyceride homeostasis;GO:1901135//carbohydrate derivative metabolic process;GO:1903300//negative regulation of hexokinase activity	--
ENSG00000084754	104.821	100.418	109.852	110.96	103.7	103.616	6258	6064	4843	4931	5279	4567	HADHA	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Lipid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko00062//Fatty acid elongation;ko00650//Butanoate metabolism"	K07515;K07515;K07515;K07515;K07515;K07515;K07515;K07515;K07515;K07515	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0042645//mitochondrial nucleoid	"GO:0000062//fatty-acyl-CoA binding;GO:0003824//catalytic activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0044877//protein-containing complex binding;GO:0051287//NAD binding;GO:0070403//NAD+ binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0032868//response to insulin;GO:0035965//cardiolipin acyl-chain remodeling;GO:0044255//cellular lipid metabolic process	--
ENSG00000084764	14.634	14.634	18.641	16.964	17.37	19.653	560	547	525	445	528	545	MAPRE3	microtubule associated protein RP/EB family member 3 [Source:HGNC Symbol;Acc:HGNC:6892]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0035371//microtubule plus-end;GO:0048471//perinuclear region of cytoplasm;GO:0051233//spindle midzone;GO:1905721//mitotic spindle astral microtubule end	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0051010//microtubule plus-end binding	"GO:0007049//cell cycle;GO:0008104//protein localization;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031113//regulation of microtubule polymerization;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051225//spindle assembly;GO:0051301//cell division;GO:1903033//positive regulation of microtubule plus-end binding;GO:1904825//protein localization to microtubule plus-end"	--
ENSG00000084774	14.482	14.729	14.486	15.043	16.736	15.132	2096	2143	1590	1639	1951	1447	CAD	"carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Source:HGNC Symbol;Acc:HGNC:1424]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K11540;K11540;K11540	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004070//aspartate carbamoyltransferase activity;GO:0004088//carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0004151//dihydroorotase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0016743//carboxyl- or carbamoyltransferase activity;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016874//ligase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070335//aspartate binding"	GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006225//UDP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0006541//glutamine metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0008152//metabolic process;GO:0018107//peptidyl-threonine phosphorylation;GO:0019240//citrulline biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044205//'de novo' UMP biosynthetic process;GO:0044238//primary metabolic process;GO:0044281//small molecule metabolic process;GO:0046777//protein autophosphorylation;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000085063	196.391	204.654	197.15	162.536	160.996	165.695	7050.25	6917	5253	4154	4781.81	4483.84	CD59	CD59 molecule (CD59 blood group) [Source:HGNC Symbol;Acc:HGNC:1689]	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04640//Hematopoietic cell lineage;ko04610//Complement and coagulation cascades	K04008;K04008	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031982//vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0001848//complement binding;GO:0005515//protein binding	GO:0001971//negative regulation of activation of membrane attack complex;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0030449//regulation of complement activation;GO:1903659//regulation of complement-dependent cytotoxicity	--
ENSG00000085117	20.153	22.403	19.405	23.076	20.325	21.891	732	821.67	563	550	662	538	CD82	CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K06509	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000085185	4.618	5.31	7.32	5.511	5.56	6.72	545	598	549	431	538	505	BCORL1	BCL6 corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:25657]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0006325//chromatin organization	--
ENSG00000085224	5.397	3.06	2.577	3.483	3.005	3.425	967	494	331	285	416	415	ATRX	ATRX chromatin remodeler [Source:HGNC Symbol;Acc:HGNC:886]	-	-	-	-	"GO:0000228//nuclear chromosome;GO:0000779//condensed chromosome, centromeric region;GO:0000781//chromosome, telomeric region;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0016604//nuclear body;GO:0016605//PML body;GO:0043233//organelle lumen;GO:0099115//chromosome, subtelomeric region"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015616//DNA translocase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0070087//chromo shadow domain binding;GO:0140658//ATP-dependent chromatin remodeler activity	"GO:0000212//meiotic spindle organization;GO:0006281//DNA repair;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030900//forebrain development;GO:0031297//replication fork processing;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0035128//post-embryonic forelimb morphogenesis;GO:0035264//multicellular organism growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060009//Sertoli cell development;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0070198//protein localization to chromosome, telomeric region;GO:0072520//seminiferous tubule development;GO:0072711//cellular response to hydroxyurea;GO:1900112//regulation of histone H3-K9 trimethylation;GO:1901581//negative regulation of telomeric RNA transcription from RNA pol II promoter;GO:1901582//positive regulation of telomeric RNA transcription from RNA pol II promoter;GO:1904908//negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric"	--
ENSG00000085231	8.669	7.411	8.922	9.075	7.109	11.095	176.25	123.73	144.81	127.16	123	170.61	AK6	adenylate kinase 6 [Source:HGNC Symbol;Acc:HGNC:49151]	Metabolism;Metabolism;Genetic Information Processing	Global and overview maps;Nucleotide metabolism;Translation	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko03008//Ribosome biogenesis in eukaryotes	K18532;K18532;K18532	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016887//ATP hydrolysis activity;GO:0050145//nucleoside monophosphate kinase activity	GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000085265	0	0	0	0	0.015	0	0	0	0	0	2	0	FCN1	ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031232//extrinsic component of external side of plasma membrane;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1904813//ficolin-1-rich granule lumen;GO:1905370//serine-type endopeptidase complex	GO:0001664//G protein-coupled receptor binding;GO:0003823//antigen binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0038187//pattern recognition receptor activity;GO:0046872//metal ion binding;GO:0097367//carbohydrate derivative binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0034394//protein localization to cell surface;GO:0043654//recognition of apoptotic cell;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell;GO:1903028//positive regulation of opsonization"	--
ENSG00000085274	5.173	4.151	3.824	3.896	3.477	3.755	388	306	193	193	198	192	MYNN	myoneurin [Source:HGNC Symbol;Acc:HGNC:14955]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:1990830//cellular response to leukemia inhibitory factor	ZBTB
ENSG00000085276	0.61	0.383	0.581	0.579	0.296	0.431	63	38	34	37	26	31	MECOM	MDS1 and EVI1 complex locus [Source:HGNC Symbol;Acc:HGNC:3498]	Metabolism;Human Diseases;Environmental Information Processing;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Signal transduction;Cancer: specific types;Amino acid metabolism	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05220//Chronic myeloid leukemia;ko00310//Lysine degradation	K04462;K04462;K04462;K04462;K04462	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific)"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0043069//negative regulation of programmed cell death;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0051567//histone H3-K9 methylation;GO:0051726//regulation of cell cycle;GO:0070828//heterochromatin organization;GO:0071425//hematopoietic stem cell proliferation"	zf-C2H2
ENSG00000085365	29.567	23.52	26.513	23.423	22.372	27.974	1669	1431	1102	947	1026	1100	SCAMP1	secretory carrier membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:10563]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0030285//integral component of synaptic vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0035579//specific granule membrane;GO:0042589//zymogen granule membrane;GO:0045202//synapse;GO:0055038//recycling endosome membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0015031//protein transport	--
ENSG00000085377	15.127	14.517	15.073	15.08	14.35	13.5	1279	1209	967	953	1054	829	PREP	prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K01322	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070012//oligopeptidase activity	GO:0006508//proteolysis	--
ENSG00000085382	4.498	4.871	4.052	3.565	4.174	5.279	423	378	284	242	267	296	HACE1	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21033]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016604//nuclear body;GO:0032580//Golgi cisterna membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0016601//Rac protein signal transduction;GO:0030334//regulation of cell migration;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0061025//membrane fusion;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000085415	5.389	5.33	5.483	4.899	4.903	4.388	343	305	230	202	233	210	SEH1L	SEH1 like nucleoporin [Source:HGNC Symbol;Acc:HGNC:30379]	Human Diseases;Environmental Information Processing;Genetic Information Processing	Neurodegenerative disease;Signal transduction;Translation	ko05014//Amyotrophic lateral sclerosis;ko04150//mTOR signaling pathway;ko03013//Nucleocytoplasmic transport	K14299;K14299;K14299	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005694//chromosome;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031080//nuclear pore outer ring;GO:0035859//Seh1-associated complex;GO:0061700//GATOR2 complex"	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007080//mitotic metaphase plate congression;GO:0015031//protein transport;GO:0031503//protein-containing complex localization;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0050830//defense response to Gram-positive bacterium;GO:0051028//mRNA transport;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:1904262//negative regulation of TORC1 signaling;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000085433	6.031	5.375	6.178	4.763	3.603	6.418	529	436	347	303	267	337	WDR47	WD repeat domain 47 [Source:HGNC Symbol;Acc:HGNC:29141]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding	-	--
ENSG00000085449	49.171	46.017	43.815	33.136	37.849	40.541	4698.7	4403.82	3092.26	2345.49	3024.61	2805.9	WDFY1	WD repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20451]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway	--
ENSG00000085465	0.263	0.349	0.297	0.356	0.208	0.241	12	16	10	12	8	8	OVGP1	oviductal glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:8524]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0035805//egg coat;GO:0043231//intracellular membrane-bounded organelle;GO:0098595//perivitelline space	GO:0004568//chitinase activity;GO:0008061//chitin binding	GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process;GO:0007338//single fertilization;GO:0007565//female pregnancy;GO:2000360//negative regulation of binding of sperm to zona pellucida	--
ENSG00000085491	9.674	9.057	8.867	8.046	8.375	11.365	721	676	514	450	528	587	SLC25A24	solute carrier family 25 member 24 [Source:HGNC Symbol;Acc:HGNC:20662]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005347//ATP transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006839//mitochondrial transport;GO:0010941//regulation of cell death;GO:0015867//ATP transport;GO:0034599//cellular response to oxidative stress;GO:0055085//transmembrane transport;GO:0071277//cellular response to calcium ion	--
ENSG00000085511	4.76	4.46	3.751	3.693	3.976	4.499	533	499	309	306	376	365	MAP3K4	mitogen-activated protein kinase kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6856]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04010//MAPK signaling pathway;ko04912//GnRH signaling pathway	K04428;K04428	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001890//placenta development;GO:0006468//protein phosphorylation;GO:0010225//response to UV-C;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0019100//male germ-line sex determination;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035556//intracellular signal transduction;GO:0043507//positive regulation of JUN kinase activity;GO:0051973//positive regulation of telomerase activity;GO:0060718//chorionic trophoblast cell differentiation;GO:1900745//positive regulation of p38MAPK cascade;GO:1904355//positive regulation of telomere capping	--
ENSG00000085514	0.123	0.151	0.897	0.205	0.045	0.216	3	4	14	4	1	3	PILRA	paired immunoglobin like type 2 receptor alpha [Source:HGNC Symbol;Acc:HGNC:20396]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K15411	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042288//MHC class I protein binding	GO:0007165//signal transduction	--
ENSG00000085552	18.312	16.874	17.204	11.676	13.347	13.814	1538	1425	1066	727	948	845	IGSF9	immunoglobulin superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:18132]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0045202//synapse;GO:0060077//inhibitory synapse	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0016358//dendrite development;GO:0030154//cell differentiation;GO:0050807//regulation of synapse organization;GO:0070593//dendrite self-avoidance	--
ENSG00000085563	0.512	0.508	0.747	0.538	0.497	0.381	52	50	54	39	42	26	ABCB1	ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Cancer: specific types;Digestive system;Membrane transport	ko05206//MicroRNAs in cancer;ko05226//Gastric cancer;ko04976//Bile secretion;ko02010//ABC transporters	K05658;K05658;K05658;K05658	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0098591//external side of apical plasma membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0031625//ubiquitin protein ligase binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0090554//phosphatidylcholine floppase activity;GO:0090555//phosphatidylethanolamine flippase activity;GO:0099038//ceramide floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140328//floppase activity;GO:0140359//ABC-type transporter activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006869//lipid transport;GO:0009410//response to xenobiotic stimulus;GO:0045332//phospholipid translocation;GO:0046865//terpenoid transport;GO:0047484//regulation of response to osmotic stress;GO:0055085//transmembrane transport;GO:0070633//transepithelial transport;GO:0072089//stem cell proliferation;GO:0099040//ceramide translocation;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1901529//positive regulation of anion channel activity;GO:1905039//carboxylic acid transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane;GO:1990962//xenobiotic transport across blood-brain barrier;GO:2001225//regulation of chloride transport	--
ENSG00000085644	4.692	4.397	5.161	4.989	5.73	4.803	308	272	243	244	309	222	ZNF213	zinc finger protein 213 [Source:HGNC Symbol;Acc:HGNC:13005]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000085662	35.034	35.788	36.867	38.067	33.701	32.694	991	1019	772	800	807	676	AKR1B1	aldo-keto reductase family 1 member B [Source:HGNC Symbol;Acc:HGNC:381]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko00040//Pentose and glucuronate interconversions;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00790//Folate biosynthesis	K00011;K00011;K00011;K00011;K00011;K00011	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0001758//retinal dehydrogenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0036130//prostaglandin H2 endoperoxidase reductase activity;GO:0043795//glyceraldehyde oxidoreductase activity;GO:0047655//allyl-alcohol dehydrogenase activity;GO:0047956//glycerol dehydrogenase [NADP+] activity;GO:0052650//NADP-retinol dehydrogenase activity	GO:0001523//retinoid metabolic process;GO:0002070//epithelial cell maturation;GO:0003091//renal water homeostasis;GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0022900//electron transport chain;GO:0035809//regulation of urine volume;GO:0042572//retinol metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0046370//fructose biosynthetic process;GO:0071475//cellular hyperosmotic salinity response;GO:0072205//metanephric collecting duct development	--
ENSG00000085719	31.715	28.984	28.024	29.502	29.894	30.735	3084	2726	2001	1948	2335	2101	CPNE3	copine 3 [Source:HGNC Symbol;Acc:HGNC:2316]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0035577//azurophil granule membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0006468//protein phosphorylation;GO:0030335//positive regulation of cell migration;GO:0038128//ERBB2 signaling pathway;GO:0071277//cellular response to calcium ion;GO:0071363//cellular response to growth factor stimulus	--
ENSG00000085721	14.947	14.559	14.155	12.636	14.231	15.458	1016	1040	730	641	804	765	RRN3	"RRN3 homolog, RNA polymerase I transcription factor [Source:HGNC Symbol;Acc:HGNC:30346]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0001042//RNA polymerase I core binding;GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0001181//RNA polymerase I general transcription initiation factor activity;GO:0070063//RNA polymerase binding	"GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0001701//in utero embryonic development;GO:0006352//DNA-templated transcription, initiation;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0007000//nucleolus organization;GO:0007028//cytoplasm organization;GO:0008283//cell population proliferation;GO:0042254//ribosome biogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048872//homeostasis of number of cells;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:2000142//regulation of DNA-templated transcription, initiation"	--
ENSG00000085733	44.664	47.459	43.34	41.884	46.49	44.296	2898	3070	2125	1993	2500	2074	CTTN	cortactin [Source:HGNC Symbol;Acc:HGNC:3338]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko05205//Proteoglycans in cancer;ko04530//Tight junction;ko05100//Bacterial invasion of epithelial cells	K06106;K06106;K06106;K06106;K06106	GO:0001726//ruffle;GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030427//site of polarized growth;GO:0030863//cortical cytoskeleton;GO:0030864//cortical actin cytoskeleton;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0110165//cellular anatomical entity;GO:1990023//mitotic spindle midzone	GO:0005515//protein binding;GO:0005522//profilin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	"GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006930//substrate-dependent cell migration, cell extension;GO:0030041//actin filament polymerization;GO:0030516//regulation of axon extension;GO:0030833//regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0031532//actin cytoskeleton reorganization;GO:0045987//positive regulation of smooth muscle contraction;GO:0048041//focal adhesion assembly;GO:0048812//neuron projection morphogenesis;GO:0048870//cell motility;GO:0097062//dendritic spine maintenance;GO:0097581//lamellipodium organization;GO:1903146//regulation of autophagy of mitochondrion;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000085741	0.101	0.126	0.034	0.274	0.24	0.279	4	5	1	8	8	8	WNT11	Wnt family member 11 [Source:HGNC Symbol;Acc:HGNC:12776]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384;K01384	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031012//extracellular matrix	GO:0005096//GTPase activator activity;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity	"GO:0001649//osteoblast differentiation;GO:0001822//kidney development;GO:0001837//epithelial to mesenchymal transition;GO:0003138//primary heart field specification;GO:0003139//secondary heart field specification;GO:0003151//outflow tract morphogenesis;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0006468//protein phosphorylation;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0007275//multicellular organism development;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030282//bone mineralization;GO:0030308//negative regulation of cell growth;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0031667//response to nutrient levels;GO:0032147//activation of protein kinase activity;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0034394//protein localization to cell surface;GO:0035567//non-canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045165//cell fate commitment;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048341//paraxial mesoderm formation;GO:0048570//notochord morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048844//artery morphogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0060021//roof of mouth development;GO:0060028//convergent extension involved in axis elongation;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060197//cloacal septation;GO:0060412//ventricular septum morphogenesis;GO:0060484//lung-associated mesenchyme development;GO:0060548//negative regulation of cell death;GO:0060675//ureteric bud morphogenesis;GO:0060775//planar cell polarity pathway involved in gastrula mediolateral intercalation;GO:0061037//negative regulation of cartilage development;GO:0061053//somite development;GO:0061101//neuroendocrine cell differentiation;GO:0062009//secondary palate development;GO:0070830//bicellular tight junction assembly;GO:0071260//cellular response to mechanical stimulus;GO:0071300//cellular response to retinoic acid;GO:0072177//mesonephric duct development;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0090037//positive regulation of protein kinase C signaling;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090272//negative regulation of fibroblast growth factor production"	--
ENSG00000085760	8.214	8.097	7.588	6.689	7.073	7.175	403	398	269	247	299	259	MTIF2	mitochondrial translational initiation factor 2 [Source:HGNC Symbol;Acc:HGNC:7441]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0008135//translation factor activity, RNA binding;GO:0043024//ribosomal small subunit binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0032790//ribosome disassembly;GO:0070124//mitochondrial translational initiation	--
ENSG00000085788	27.876	26.613	25.678	19.773	28.263	28.056	2350	2218	1672	1289	1498	1460	DDHD2	DDHD domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29106]	-	-	-	-	GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0034451//centriolar satellite	GO:0004620//phospholipase activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0007626//locomotory behavior;GO:0008542//visual learning;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0034389//lipid droplet organization;GO:0090141//positive regulation of mitochondrial fission	--
ENSG00000085831	0.436	0.453	0.648	0.909	0.461	0.387	21	22	21	28	21	11	TTC39A	tetratricopeptide repeat domain 39A [Source:HGNC Symbol;Acc:HGNC:18657]	-	-	-	-	GO:0005813//centrosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000085832	10.897	11.157	11.518	6.82	8.975	10.562	1167	1201	911	541	812	823	EPS15	epidermal growth factor receptor pathway substrate 15 [Source:HGNC Symbol;Acc:HGNC:3419]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12472	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016235//aggresome;GO:0030132//clathrin coat of coated pit;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006895//Golgi to endosome transport;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016050//vesicle organization;GO:0016197//endosomal transport;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0032456//endocytic recycling;GO:0046718//viral entry into host cell;GO:0048268//clathrin coat assembly	--
ENSG00000085840	0.525	0.389	0.167	0.104	0.165	0.172	34	25	8	5	9	8	ORC1	origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02603	"GO:0000781//chromosome, telomeric region;GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005829//cytosol"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003688//DNA replication origin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0033314//mitotic DNA replication checkpoint signaling	--
ENSG00000085871	32.789	37.808	33.317	42.274	37.642	33.524	514	591	386	494	494	382	MGST2	microsomal glutathione S-transferase 2 [Source:HGNC Symbol;Acc:HGNC:7063]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004364//glutathione transferase activity;GO:0004464//leukotriene-C4 synthase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0043295//glutathione binding	GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006750//glutathione biosynthetic process;GO:0019370//leukotriene biosynthetic process;GO:0046466//membrane lipid catabolic process;GO:0050729//positive regulation of inflammatory response;GO:0050790//regulation of catalytic activity;GO:0098869//cellular oxidant detoxification	--
ENSG00000085872	13.327	13.442	14.141	13.275	14.832	14.852	1126.83	1142.38	883.1	831.44	1059.3	913.49	CHERP	calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symbol;Acc:HGNC:16930]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12841	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0006396//RNA processing;GO:0006874//cellular calcium ion homeostasis;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000085978	5.625	6.213	5.624	5.752	6.993	7.096	381	422	271	285	367	332	ATG16L1	autophagy related 16 like 1 [Source:HGNC Symbol;Acc:HGNC:21498]	Human Diseases;Organismal Systems;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Immune system;Transport and catabolism;Transport and catabolism	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04136//Autophagy - other	K17890;K17890;K17890;K17890	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005930//axoneme;GO:0016020//membrane;GO:0034045//phagophore assembly site membrane;GO:0034274//Atg12-Atg5-Atg16 complex;GO:0036020//endolysosome membrane;GO:0120095//vacuole-isolation membrane contact site	GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042802//identical protein binding;GO:0051020//GTPase binding	GO:0000045//autophagosome assembly;GO:0006497//protein lipidation;GO:0006501//C-terminal protein lipidation;GO:0006914//autophagy;GO:0010508//positive regulation of autophagy;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0016237//lysosomal microautophagy;GO:0034497//protein localization to phagophore assembly site;GO:0039689//negative stranded viral RNA replication;GO:0051607//defense response to virus;GO:0061739//protein lipidation involved in autophagosome assembly;GO:0098792//xenophagy	--
ENSG00000085982	6.736	8.01	6.582	6.023	7.035	6.76	792	845	567	527	660	581	USP40	ubiquitin specific peptidase 40 [Source:HGNC Symbol;Acc:HGNC:20069]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability	--
ENSG00000085998	30.36	31.832	35.951	37.231	36.293	34.894	1690	1786	1491.03	1539.56	1703.61	1413	POMGNT1	"protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) [Source:HGNC Symbol;Acc:HGNC:19139]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K09666;K09666	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	"GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing	--
ENSG00000085999	0.463	0.421	0.324	0.351	0.238	0.255	14.37	27	4	10	5.32	6.29	RAD54L	RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10875	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015616//DNA translocase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0046872//metal ion binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0007131//reciprocal meiotic recombination;GO:0008340//determination of adult lifespan;GO:0009410//response to xenobiotic stimulus;GO:0010212//response to ionizing radiation;GO:0032508//DNA duplex unwinding;GO:0045003//double-strand break repair via synthesis-dependent strand annealing;GO:0051276//chromosome organization;GO:0051321//meiotic cell cycle	--
ENSG00000086015	7.187	7.516	7.018	7.407	7.451	7.945	808	849	611	626	744	627	MAST2	microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019902//phosphatase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032655//regulation of interleukin-12 production;GO:0035556//intracellular signal transduction;GO:0048515//spermatid differentiation	--
ENSG00000086061	100.352	93.179	95.819	77.632	75.643	76.718	4827	4505	3404	2766	3074	2685	DNAJA1	DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09502	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098554//cytoplasmic side of endoplasmic reticulum membrane	GO:0001664//G protein-coupled receptor binding;GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030544//Hsp70 protein binding;GO:0030957//Tat protein binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0055131//C3HC4-type RING finger domain binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0009408//response to heat;GO:0031397//negative regulation of protein ubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043508//negative regulation of JUN kinase activity;GO:0051223//regulation of protein transport;GO:0070585//protein localization to mitochondrion;GO:1903748//negative regulation of establishment of protein localization to mitochondrion;GO:1905259//negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000086062	51.845	57.534	48.288	41.667	47.112	42.674	4488	4978	3070	2662	3430	2678	B4GALT1	"beta-1,4-galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:924]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00514//Other types of O-glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis;ko00052//Galactose metabolism;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K07966;K07966;K07966;K07966;K07966;K07966;K07966;K07966	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030057//desmosome;GO:0030175//filopodium;GO:0030667//secretory granule membrane;GO:0031526//brush border membrane;GO:0031984//organelle subcompartment;GO:0032580//Golgi cisterna membrane;GO:0035577//azurophil granule membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0098588//bounding membrane of organelle	"GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0004461//lactose synthase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008378//galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0035250//UDP-galactosyltransferase activity;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding"	GO:0002064//epithelial cell development;GO:0002526//acute inflammatory response;GO:0005975//carbohydrate metabolic process;GO:0005989//lactose biosynthetic process;GO:0006012//galactose metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006629//lipid metabolic process;GO:0007155//cell adhesion;GO:0007339//binding of sperm to zona pellucida;GO:0007341//penetration of zona pellucida;GO:0008285//negative regulation of cell population proliferation;GO:0009101//glycoprotein biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0030198//extracellular matrix organization;GO:0042060//wound healing;GO:0043065//positive regulation of apoptotic process;GO:0045136//development of secondary sexual characteristics;GO:0050900//leukocyte migration;GO:0060046//regulation of acrosome reaction;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060055//angiogenesis involved in wound healing;GO:0070085//glycosylation;GO:1901137//carbohydrate derivative biosynthetic process	--
ENSG00000086065	28.058	27.504	27.56	21.997	22.171	24.486	1110	1094	806	645	741	705	CHMP5	charged multivesicular body protein 5 [Source:HGNC Symbol;Acc:HGNC:26942]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12198;K12198	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0001778//plasma membrane repair;GO:0001919//regulation of receptor recycling;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007040//lysosome organization;GO:0007080//mitotic metaphase plate congression;GO:0008333//endosome to lysosome transport;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0031468//nuclear membrane reassembly;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046755//viral budding;GO:0046761//viral budding from plasma membrane;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071222//cellular response to lipopolysaccharide;GO:0071225//cellular response to muramyl dipeptide;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904903//ESCRT III complex disassembly	--
ENSG00000086102	10.55	11.176	10.911	8.548	9.303	8.992	885	965	691	543	682	559	NFX1	"nuclear transcription factor, X-box binding 1 [Source:HGNC Symbol;Acc:HGNC:7803]"	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K12236	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0016567//protein ubiquitination;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0051865//protein autoubiquitination"	zf-NF-X1
ENSG00000086159	0	0	0	0	0	0	0	0	0	0	0	0	AQP6	aquaporin 6 [Source:HGNC Symbol;Acc:HGNC:639]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015112//nitrate transmembrane transporter activity;GO:0015250//water channel activity;GO:0015267//channel activity	GO:0003097//renal water transport;GO:0006833//water transport;GO:0015670//carbon dioxide transport;GO:0015706//nitrate transport;GO:0042476//odontogenesis;GO:0055085//transmembrane transport	--
ENSG00000086189	7.499	8.733	8.066	7.102	6.878	8.748	263.78	300.75	214.56	192.77	223.44	249.78	DIMT1	DIM1 rRNA methyltransferase and ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:30217]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0016740//transferase activity;GO:0052909//18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"	GO:0000154//rRNA modification;GO:0006364//rRNA processing;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:2000234//positive regulation of rRNA processing	--
ENSG00000086200	7.867	5.434	6.82	6.338	4.642	4.885	592	472	386	277	341	308	IPO11	importin 11 [Source:HGNC Symbol;Acc:HGNC:20628]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K25201	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006610//ribosomal protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000086205	0.022	0.022	0	0.03	0.077	0	1	1	0	1	3	0	FOLH1	folate hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3788]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Amino acid metabolism;Digestive system	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism;ko04977//Vitamin digestion and absorption"	K14592;K14592;K14592	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding;GO:1904492//Ac-Asp-Glu binding;GO:1904493//tetrahydrofolyl-poly(glutamate) polymer binding	GO:0006508//proteolysis;GO:0006760//folic acid-containing compound metabolic process;GO:0008152//metabolic process;GO:0035609//C-terminal protein deglutamylation	--
ENSG00000086232	31.781	30.866	35.762	27.377	26.707	31.322	2695.22	2838.54	2091.17	1855.36	2064.42	1852.42	EIF2AK1	eukaryotic translation initiation factor 2 alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:24921]	Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases	"Infectious disease: viral;Folding, sorting and degradation;Infectious disease: viral;Infectious disease: viral"	ko05168//Herpes simplex virus 1 infection;ko04141//Protein processing in endoplasmic reticulum;ko05160//Hepatitis C;ko05162//Measles	K16194;K16194;K16194;K16194	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003743//translation initiation factor activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0002526//acute inflammatory response;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0008285//negative regulation of cell population proliferation;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0010999//regulation of eIF2 alpha phosphorylation by heme;GO:0016310//phosphorylation;GO:0017148//negative regulation of translation;GO:0030225//macrophage differentiation;GO:0045993//negative regulation of translational initiation by iron;GO:0046501//protoporphyrinogen IX metabolic process;GO:0046777//protein autophosphorylation;GO:0046984//regulation of hemoglobin biosynthetic process;GO:0046986//negative regulation of hemoglobin biosynthetic process;GO:0055072//iron ion homeostasis;GO:0140467//integrated stress response signaling;GO:0140468//HRI-mediated signaling;GO:1990641//response to iron ion starvation	--
ENSG00000086288	0	0.021	0	0	0	0	0	1	0	0	0	0	NME8	NME/NM23 family member 8 [Source:HGNC Symbol;Acc:HGNC:16473]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005930//axoneme;GO:0016607//nuclear speck;GO:0036157//outer dynein arm;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097598//sperm cytoplasmic droplet	GO:0008017//microtubule binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0034614//cellular response to reactive oxygen species;GO:0060271//cilium assembly	--
ENSG00000086289	16.406	17.535	19.898	19.518	20.292	19.464	823	911	739	728	857	716	EPDR1	ependymin related 1 [Source:HGNC Symbol;Acc:HGNC:17572]	-	-	-	-	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0110165//cellular anatomical entity	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:1905573//ganglioside GM1 binding	GO:0007160//cell-matrix adhesion;GO:1990764//myofibroblast contraction	--
ENSG00000086300	0.448	0.345	0.194	0.253	0.37	0.172	18	17	7	6	15	4	SNX10	sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:14974]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030141//secretory granule;GO:0031313//extrinsic component of endosome membrane;GO:0090651//apical cytoplasm	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0051117//ATPase binding	GO:0001696//gastric acid secretion;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0030316//osteoclast differentiation;GO:0035630//bone mineralization involved in bone maturation;GO:0044691//tooth eruption;GO:0045453//bone resorption;GO:0046849//bone remodeling;GO:0055074//calcium ion homeostasis;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0071539//protein localization to centrosome;GO:0097178//ruffle assembly;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000086475	37.267	35.555	38.334	39.789	35.123	40.043	1515	1508	1238	1126	1212	1262	SEPHS1	selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00450//Selenocompound metabolism	K01008;K01008	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031965//nuclear membrane	"GO:0000166//nucleotide binding;GO:0004756//selenide, water dikinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	GO:0006464//cellular protein modification process;GO:0016260//selenocysteine biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000086504	48.282	52.447	55.516	66.364	53.223	64.64	984	1069	839	989	902	960	MRPL28	mitochondrial ribosomal protein L28 [Source:HGNC Symbol;Acc:HGNC:14484]	Genetic Information Processing	Translation	ko03010//Ribosome	K02902	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000086506	0.274	0.091	0.371	0.74	0.757	0.502	3	1	3	6	7	4	HBQ1	hemoglobin subunit theta 1 [Source:HGNC Symbol;Acc:HGNC:4833]	-	-	-	-	GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000086544	6.755	7.516	7.599	6.304	6.474	7.556	473	529	393	327	383	385	ITPKC	inositol-trisphosphate 3-kinase C [Source:HGNC Symbol;Acc:HGNC:14897]	Metabolism;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00911;K00911;K00911;K00911	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000166//nucleotide binding;GO:0000828//inositol hexakisphosphate kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity"	GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000086548	0	0	0	0	0.11	0	0	0	0	0	5	0	CEACAM6	CEA cell adhesion molecule 6 [Source:HGNC Symbol;Acc:HGNC:1818]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0030335//positive regulation of cell migration;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:1904906//positive regulation of endothelial cell-matrix adhesion via fibronectin;GO:2000811//negative regulation of anoikis	--
ENSG00000086570	0.029	0.023	0.013	0.095	0.062	0.054	9	7	1	8	13	12	FAT2	FAT atypical cadherin 2 [Source:HGNC Symbol;Acc:HGNC:3596]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0010631//epithelial cell migration;GO:0031589//cell-substrate adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000086589	16.001	16.628	15.333	15.497	16.942	18.054	763	797	540	544	679	623	RBM22	RNA binding motif protein 22 [Source:HGNC Symbol;Acc:HGNC:25503]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12872	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0036002//pre-mRNA binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0033120//positive regulation of RNA splicing;GO:0042307//positive regulation of protein import into nucleus;GO:0045292//mRNA cis splicing, via spliceosome;GO:0046827//positive regulation of protein export from nucleus;GO:0071466//cellular response to xenobiotic stimulus"	--
ENSG00000086598	93.595	91.201	83.58	81.905	81.017	77.972	4923	4835	3255	3199	3597	2992	TMED2	transmembrane p24 trafficking protein 2 [Source:HGNC Symbol;Acc:HGNC:16996]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042589//zymogen granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001843//neural tube closure;GO:0001892//embryonic placenta development;GO:0001893//maternal placenta development;GO:0001947//heart looping;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0008104//protein localization;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032525//somite rostral/caudal axis specification;GO:0034260//negative regulation of GTPase activity;GO:0035264//multicellular organism growth;GO:0035459//vesicle cargo loading;GO:0036342//post-anal tail morphogenesis;GO:0036499//PERK-mediated unfolded protein response;GO:0048205//COPI coating of Golgi vesicle;GO:0048208//COPII vesicle coating;GO:0048598//embryonic morphogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060716//labyrinthine layer blood vessel development;GO:0060717//chorion development;GO:0072659//protein localization to plasma membrane;GO:0090158//endoplasmic reticulum membrane organization;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:1905069//allantois development;GO:2000638//regulation of SREBP signaling pathway	--
ENSG00000086619	2.323	1.874	1.948	2.218	2.464	1.95	239	176	149	140	194	147	ERO1B	endoplasmic reticulum oxidoreductase 1 beta [Source:HGNC Symbol;Acc:HGNC:14355]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10976	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity;GO:0016972//thiol oxidase activity;GO:0051082//unfolded protein binding;GO:0071949//FAD binding	GO:0006457//protein folding;GO:0034975//protein folding in endoplasmic reticulum	--
ENSG00000086666	51.823	46.759	46.461	43.258	44.158	45.984	1343	1246	901	849	932	861	ZFAND6	zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding	GO:0006625//protein targeting to peroxisome;GO:0006915//apoptotic process;GO:0015031//protein transport;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000086696	459.642	458.478	618.133	838.659	677.807	832.775	13498	13529	13423	18294	16777	17807	HSD17B2	hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K13368;K13368;K13368	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047006//17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0001701//in utero embryonic development;GO:0001890//placenta development;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0032526//response to retinoic acid	--
ENSG00000086712	5.438	4.563	5.043	3.268	3.624	4.967	492	415	337	219	277	327	TXLNG	taxilin gamma [Source:HGNC Symbol;Acc:HGNC:18578]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0019905//syntaxin binding;GO:0140297//DNA-binding transcription factor binding	GO:0007049//cell cycle;GO:0010564//regulation of cell cycle process;GO:0030500//regulation of bone mineralization;GO:0051726//regulation of cell cycle	--
ENSG00000086717	0.107	0.042	0.057	0.176	0	0	6	2	2	6	0	0	PPEF1	protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]	Organismal Systems	Sensory system	ko04745//Phototransduction - fly	K13807	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0050906//detection of stimulus involved in sensory perception	--
ENSG00000086730	0.026	0.128	0	0.231	0.135	0.078	1	5	0	6	4	2	LAT2	linker for activation of T cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042169//SH2 domain binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002764//immune response-regulating signaling pathway;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0042113//B cell activation;GO:0043303//mast cell degranulation;GO:0050853//B cell receptor signaling pathway	--
ENSG00000086758	46.519	51.006	48.928	39.567	46.411	43.813	9990	10652	7526	6118	7987	6494	HUWE1	"HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:30892]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10592	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007030//Golgi organization;GO:0010637//negative regulation of mitochondrial fusion;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0030154//cell differentiation;GO:0031398//positive regulation of protein ubiquitination;GO:0032922//circadian regulation of gene expression;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0048511//rhythmic process;GO:0061025//membrane fusion;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000086827	5.9	5.775	6.798	5.278	4.701	4.751	341	340	247	233	235	206	ZW10	zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005819//spindle;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0070939//Dsl1/NZR complex;GO:1990423//RZZ complex"	GO:0005515//protein binding;GO:0019237//centromeric DNA binding	"GO:0000070//mitotic sister chromatid segregation;GO:0000132//establishment of mitotic spindle orientation;GO:0000278//mitotic cell cycle;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007096//regulation of exit from mitosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0034501//protein localization to kinetochore;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0065003//protein-containing complex assembly"	--
ENSG00000086848	16.419	16.858	17.74	15.937	16.274	17.484	823.24	843	624.84	552	674	632.41	ALG9	"ALG9 alpha-1,2-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:15672]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03846;K03846;K03846	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0052918//dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0052926//dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0097502//mannosylation	--
ENSG00000086967	0.455	0.559	0.199	0.343	0.459	0.404	34	42	11	19	29	22	MYBPC2	myosin binding protein C2 [Source:HGNC Symbol;Acc:HGNC:7550]	-	-	-	-	GO:0005829//cytosol;GO:0032982//myosin filament	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0006936//muscle contraction;GO:0007155//cell adhesion	--
ENSG00000086991	3.744	2.582	2.563	1.614	1.92	2.316	160	107	62	49	61	51	NOX4	NADPH oxidase 4 [Source:HGNC Symbol;Acc:HGNC:7891]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Endocrine and metabolic disease;Endocrine and metabolic disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04936//Alcoholic liver disease;ko04933//AGE-RAGE signaling pathway in diabetic complications	K21423;K21423;K21423;K21423;K21423	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043020//NADPH oxidase complex;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0097038//perinuclear endoplasmic reticulum	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0019826//oxygen sensor activity;GO:0020037//heme binding;GO:0050660//flavin adenine dinucleotide binding;GO:0072341//modified amino acid binding;GO:1990782//protein tyrosine kinase binding	GO:0000902//cell morphogenesis;GO:0003015//heart process;GO:0006801//superoxide metabolic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007569//cell aging;GO:0008285//negative regulation of cell population proliferation;GO:0010467//gene expression;GO:0022900//electron transport chain;GO:0042554//superoxide anion generation;GO:0043406//positive regulation of MAP kinase activity;GO:0045453//bone resorption;GO:0050667//homocysteine metabolic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0055007//cardiac muscle cell differentiation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0072593//reactive oxygen species metabolic process;GO:1903409//reactive oxygen species biosynthetic process;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000087008	8.118	8.433	9.582	7.341	7.918	7.693	415	403	366	288	339	301	ACOX3	"acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121]"	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine and metabolic disease;Global and overview maps;Transport and catabolism;Endocrine system;Global and overview maps;Lipid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko04936//Alcoholic liver disease;ko01200//Carbon metabolism;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko01040//Biosynthesis of unsaturated fatty acids;ko00592//alpha-Linolenic acid metabolism	K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane	"GO:0003997//acyl-CoA oxidase activity;GO:0005504//fatty acid binding;GO:0016402//pristanoyl-CoA oxidase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088//lipid homeostasis	--
ENSG00000087053	16.92	15.702	17.378	13.702	14.237	15.342	1337.91	1216.29	997.13	814.67	923.97	864.5	MTMR2	myotubularin related protein 2 [Source:HGNC Symbol;Acc:HGNC:7450]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18081;K18081;K18081	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097060//synaptic membrane	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042802//identical protein binding;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0052866//phosphatidylinositol phosphate phosphatase activity"	GO:0002091//negative regulation of receptor internalization;GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016311//dephosphorylation;GO:0031642//negative regulation of myelination;GO:0032288//myelin assembly;GO:0045806//negative regulation of endocytosis;GO:0046488//phosphatidylinositol metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048666//neuron development;GO:0060304//regulation of phosphatidylinositol dephosphorylation;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0097062//dendritic spine maintenance;GO:2000643//positive regulation of early endosome to late endosome transport;GO:2000645//negative regulation of receptor catabolic process	--
ENSG00000087074	12.504	13.144	12.208	13.238	13.27	12.758	609	643	437	477	546	452	PPP1R15A	protein phosphatase 1 regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14019	GO:0000164//protein phosphatase type 1 complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity;GO:0019901//protein kinase binding;GO:0072542//protein phosphatase activator activity	GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0032058//positive regulation of translational initiation in response to stress;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0035308//negative regulation of protein dephosphorylation;GO:0036496//regulation of translational initiation by eIF2 alpha dephosphorylation;GO:0051726//regulation of cell cycle;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070972//protein localization to endoplasmic reticulum;GO:1902310//positive regulation of peptidyl-serine dephosphorylation;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:1903917//positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	--
ENSG00000087076	30.48	33.27	38.789	40.579	37.73	44.552	615	679	583	617	658	653	HSD17B14	hydroxysteroid 17-beta dehydrogenase 14 [Source:HGNC Symbol;Acc:HGNC:23238]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity	GO:0006629//lipid metabolic process;GO:0006706//steroid catabolic process;GO:0008202//steroid metabolic process	--
ENSG00000087077	49.217	52.162	61.197	69.496	62.88	66.052	1640	1722	1503	1717	1802	1607	TRIP6	thyroid hormone receptor interactor 6 [Source:HGNC Symbol;Acc:HGNC:12311]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12792	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0003723//RNA binding;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046966//thyroid hormone receptor binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0043009//chordate embryonic development;GO:0048041//focal adhesion assembly;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000087085	0.724	0.787	0.539	0.82	0.458	0.631	26	29	14	28	17	20	ACHE	acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108]	Organismal Systems;Metabolism	Nervous system;Lipid metabolism	ko04725//Cholinergic synapse;ko00564//Glycerophospholipid metabolism	K01049;K01049	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0031594//neuromuscular junction;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0001540//amyloid-beta binding;GO:0003990//acetylcholinesterase activity;GO:0004104//cholinesterase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity;GO:0042166//acetylcholine binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043236//laminin binding;GO:0043621//protein self-association;GO:0052689//carboxylic ester hydrolase activity	"GO:0001507//acetylcholine catabolic process in synaptic cleft;GO:0001919//regulation of receptor recycling;GO:0002076//osteoblast development;GO:0006581//acetylcholine catabolic process;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0031623//receptor internalization;GO:0032223//negative regulation of synaptic transmission, cholinergic;GO:0042135//neurotransmitter catabolic process;GO:0042982//amyloid precursor protein metabolic process;GO:0050714//positive regulation of protein secretion;GO:0060041//retina development in camera-type eye;GO:0095500//acetylcholine receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000087086	758.706	800.808	812.255	1055.726	926.664	875.08	13707	14542	10838	14128	14144	11503	FTL	ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999]	Cellular Processes;Organismal Systems;Cellular Processes	Cell growth and death;Digestive system;Cell growth and death	ko04217//Necroptosis;ko04978//Mineral absorption;ko04216//Ferroptosis	K13625;K13625;K13625	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008043//intracellular ferritin complex;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0044754//autolysosome;GO:0070062//extracellular exosome	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006880//intracellular sequestering of iron ion;GO:0055072//iron ion homeostasis	--
ENSG00000087087	28.248	27.83	30.408	26.92	30.309	29.013	1654	1682	1370	1186	1546	1263	SRRT	"serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0140262//mRNA cap binding complex binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0031047//gene silencing by RNA;GO:0031053//primary miRNA processing;GO:0046685//response to arsenic-containing substance;GO:0050769//positive regulation of neurogenesis;GO:0097150//neuronal stem cell population maintenance"	--
ENSG00000087088	10.563	10.56	14.381	10.69	11.144	13.956	178	187	176	140	156	179	BAX	"BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	"Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Folding, sorting and degradation;Endocrine and metabolic disease;Cancer: specific types;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Cell growth and death;Nervous system;Signal transduction;Endocrine and metabolic disease;Drug resistance: antineoplastic;Aging;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko04210//Apoptosis;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer;ko04215//Apoptosis - multiple species	K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159;K02159	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005757//mitochondrial permeability transition pore complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0046930//pore complex;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0097136//Bcl-2 family protein complex;GO:0097144//BAX complex;GO:0097145//BAK complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015267//channel activity;GO:0030544//Hsp70 protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:0051434//BH3 domain binding	GO:0001541//ovarian follicle development;GO:0001764//neuron migration;GO:0001776//leukocyte homeostasis;GO:0001777//T cell homeostatic proliferation;GO:0001782//B cell homeostasis;GO:0001783//B cell apoptotic process;GO:0001822//kidney development;GO:0001836//release of cytochrome c from mitochondria;GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0001974//blood vessel remodeling;GO:0002262//myeloid cell homeostasis;GO:0002352//B cell negative selection;GO:0002358//B cell homeostatic proliferation;GO:0002904//positive regulation of B cell apoptotic process;GO:0006687//glycosphingolipid metabolic process;GO:0006808//regulation of nitrogen utilization;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0007548//sex differentiation;GO:0008053//mitochondrial fusion;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0008637//apoptotic mitochondrial changes;GO:0009566//fertilization;GO:0009611//response to wounding;GO:0009636//response to toxic substance;GO:0009651//response to salt stress;GO:0009791//post-embryonic development;GO:0010212//response to ionizing radiation;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0010332//response to gamma radiation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0021854//hypothalamus development;GO:0021987//cerebral cortex development;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0032976//release of matrix enzymes from mitochondria;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0034620//cellular response to unfolded protein;GO:0034644//cellular response to UV;GO:0035108//limb morphogenesis;GO:0035234//ectopic germ cell programmed cell death;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0045136//development of secondary sexual characteristics;GO:0046666//retinal cell programmed cell death;GO:0048087//positive regulation of developmental pigmentation;GO:0048147//negative regulation of fibroblast proliferation;GO:0048515//spermatid differentiation;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0048678//response to axon injury;GO:0048872//homeostasis of number of cells;GO:0048873//homeostasis of number of cells within a tissue;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0051881//regulation of mitochondrial membrane potential;GO:0060011//Sertoli cell proliferation;GO:0060041//retina development in camera-type eye;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0060068//vagina development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070242//thymocyte apoptotic process;GO:0070584//mitochondrion morphogenesis;GO:0071310//cellular response to organic substance;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097435//supramolecular fiber organization;GO:0098586//cellular response to virus;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:1902512//positive regulation of apoptotic DNA fragmentation;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:1990117//B cell receptor apoptotic signaling pathway;GO:2001234//negative regulation of apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000087095	12.319	12.554	13.377	10.723	12.783	12.279	804	812	600	494	660	582	NLK	nemo like kinase [Source:HGNC Symbol;Acc:HGNC:29858]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes	Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04310//Wnt signaling pathway;ko04068//FoxO signaling pathway;ko04520//Adherens junction	K04468;K04468;K04468;K04468	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042169//SH2 domain binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000165//MAPK cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0042501//serine phosphorylation of STAT protein;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization"	--
ENSG00000087111	46.452	50.572	53.165	62.015	61.444	56.742	2441	2691	2079	2434	2759	2194	PIGS	phosphatidylinositol glycan anchor biosynthesis class S [Source:HGNC Symbol;Acc:HGNC:14937]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05291;K05291	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042765//GPI-anchor transamidase complex	GO:0005515//protein binding	GO:0006506//GPI anchor biosynthetic process;GO:0016255//attachment of GPI anchor to protein	--
ENSG00000087116	1.617	2.056	1.32	3.134	3.408	3.005	225	256	132	310	374	279	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif 2 [Source:HGNC Symbol;Acc:HGNC:218]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0016485//protein processing;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030324//lung development;GO:0030574//collagen catabolic process;GO:0043588//skin development	--
ENSG00000087128	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS11E	transmembrane serine protease 11E [Source:HGNC Symbol;Acc:HGNC:24465]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0050890//cognition	--
ENSG00000087152	17.73	15.437	17.544	17.302	17.201	19.139	1312	1152	945	969	1149	1049	ATXN7L3	ataxin 7 like 3 [Source:HGNC Symbol;Acc:HGNC:25416]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0033276//transcription factor TFTC complex;GO:0070461//SAGA-type complex;GO:0071819//DUBm complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030374//nuclear receptor coactivator activity;GO:0046872//metal ion binding	"GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006996//organelle organization;GO:0010390//histone monoubiquitination;GO:0016578//histone deubiquitination;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000087157	8.55	7.783	10.577	11.173	11.19	9.909	333	323	255	256	300	255	PGS1	phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K00995;K00995	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0008444//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0032049//cardiolipin biosynthetic process;GO:0046339//diacylglycerol metabolic process	--
ENSG00000087191	45.032	48.807	54.899	52.622	44.833	47.021	1241	1340	1072	1055	1032	941	PSMC5	"proteasome 26S subunit, ATPase 5 [Source:HGNC Symbol;Acc:HGNC:9552]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03066;K03066;K03066;K03066;K03066;K03066;K03066;K03066;K03066	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0016234//inclusion body;GO:0022624//proteasome accessory complex;GO:0031410//cytoplasmic vesicle;GO:0031595//nuclear proteasome complex;GO:0031597//cytosolic proteasome complex;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098794//postsynapse"	GO:0000166//nucleotide binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008134//transcription factor binding;GO:0016887//ATP hydrolysis activity;GO:0017025//TBP-class protein binding;GO:0031531//thyrotropin-releasing hormone receptor binding;GO:0036402//proteasome-activating activity;GO:0140296//general transcription initiation factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006261//DNA-dependent DNA replication;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030163//protein catabolic process;GO:0043069//negative regulation of programmed cell death;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0044085//cellular component biogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050804//modulation of chemical synaptic transmission;GO:0090261//positive regulation of inclusion body assembly;GO:1901800//positive regulation of proteasomal protein catabolic process"	--
ENSG00000087206	6.816	6.403	6.185	5.383	5.348	7.48	332	301	231	197	216	214	UIMC1	ubiquitin interaction motif containing 1 [Source:HGNC Symbol;Acc:HGNC:30298]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K20775	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0070531//BRCA1-A complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	"GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045739//positive regulation of DNA repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070537//histone H2A K63-linked deubiquitination"	--
ENSG00000087237	0	0.031	0	0	0	0	0	1	0	0	0	0	CETP	cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K16835	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031982//vesicle;GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular exosome	GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0017129//triglyceride binding;GO:0031210//phosphatidylcholine binding;GO:0120020//cholesterol transfer activity	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010874//regulation of cholesterol efflux;GO:0015914//phospholipid transport;GO:0030301//cholesterol transport;GO:0032376//positive regulation of cholesterol transport;GO:0034197//triglyceride transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0046470//phosphatidylcholine metabolic process;GO:0055088//lipid homeostasis;GO:0055091//phospholipid homeostasis;GO:0070328//triglyceride homeostasis;GO:0120009//intermembrane lipid transfer;GO:2001140//positive regulation of phospholipid transport	--
ENSG00000087245	57.279	56.758	48.26	48.62	59.36	50.865	3377	3541	2083	2126	3118	2246	MMP2	matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cardiovascular disease;Cancer: overview;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04912//GnRH signaling pathway;ko05219//Bladder cancer	K01398;K01398;K01398;K01398;K01398;K01398;K01398;K01398;K01398;K01398;K01398	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0001968//fibronectin binding;GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001542//ovulation from ovarian follicle;GO:0001553//luteinization;GO:0001666//response to hypoxia;GO:0001955//blood vessel maturation;GO:0001957//intramembranous ossification;GO:0006508//proteolysis;GO:0006979//response to oxidative stress;GO:0007162//negative regulation of cell adhesion;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007566//embryo implantation;GO:0007567//parturition;GO:0007568//aging;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0010033//response to organic substance;GO:0014012//peripheral nervous system axon regeneration;GO:0014823//response to activity;GO:0016477//cell migration;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0030574//collagen catabolic process;GO:0032526//response to retinoic acid;GO:0034097//response to cytokine;GO:0034614//cellular response to reactive oxygen species;GO:0035094//response to nicotine;GO:0035987//endodermal cell differentiation;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0043627//response to estrogen;GO:0044267//cellular protein metabolic process;GO:0045906//negative regulation of vasoconstriction;GO:0048013//ephrin receptor signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048705//skeletal system morphogenesis;GO:0048771//tissue remodeling;GO:0051602//response to electrical stimulus;GO:0055093//response to hyperoxia;GO:0060325//face morphogenesis;GO:0060346//bone trabecula formation;GO:0060740//prostate gland epithelium morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0071345//cellular response to cytokine stimulus;GO:0071347//cellular response to interleukin-1;GO:0071392//cellular response to estradiol stimulus;GO:0071492//cellular response to UV-A;GO:0071498//cellular response to fluid shear stress;GO:1904645//response to amyloid-beta;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation	--
ENSG00000087250	0	0	0	0	0	0	0	0	0	0	0	0	MT3	metallothionein 3 [Source:HGNC Symbol;Acc:HGNC:7408]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016234//inclusion body;GO:0030424//axon;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm;GO:0097449//astrocyte projection;GO:0097450//astrocyte end-foot	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016209//antioxidant activity;GO:0030295//protein kinase activator activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046870//cadmium ion binding;GO:0046872//metal ion binding	"GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0006112//energy reserve metabolic process;GO:0006707//cholesterol catabolic process;GO:0006829//zinc ion transport;GO:0006875//cellular metal ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0006915//apoptotic process;GO:0007420//brain development;GO:0010273//detoxification of copper ion;GO:0010507//negative regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010940//positive regulation of necrotic cell death;GO:0010942//positive regulation of cell death;GO:0010977//negative regulation of neuron projection development;GO:0014002//astrocyte development;GO:0016570//histone modification;GO:0019430//removal of superoxide radicals;GO:0030308//negative regulation of cell growth;GO:0030517//negative regulation of axon extension;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032095//regulation of response to food;GO:0032148//activation of protein kinase B activity;GO:0033210//leptin-mediated signaling pathway;GO:0034599//cellular response to oxidative stress;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043491//protein kinase B signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0044242//cellular lipid catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0051354//negative regulation of oxidoreductase activity;GO:0055069//zinc ion homeostasis;GO:0055073//cadmium ion homeostasis;GO:0060049//regulation of protein glycosylation;GO:0060547//negative regulation of necrotic cell death;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion;GO:0071456//cellular response to hypoxia;GO:0071732//cellular response to nitric oxide;GO:0097214//positive regulation of lysosomal membrane permeability;GO:1901215//negative regulation of neuron death;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:2000296//negative regulation of hydrogen peroxide catabolic process;GO:2000376//positive regulation of oxygen metabolic process;GO:2000378//negative regulation of reactive oxygen species metabolic process"	--
ENSG00000087253	8.303	8.186	8.433	7.739	6.509	9.821	915	858	628	608	606	758	LPCAT2	lysophosphatidylcholine acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:26032]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism	K13510;K13510;K13510	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047159//1-alkenylglycerophosphocholine O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0050200//plasmalogen synthase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006663//platelet activating factor biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0061024//membrane organization	--
ENSG00000087258	5.782	6.226	7.016	7.603	7.344	6.316	605	664	579	631	658	508	GNAO1	G protein subunit alpha o1 [Source:HGNC Symbol;Acc:HGNC:4389]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Substance dependence;Endocrine system;Nervous system;Endocrine system;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Infectious disease: parasitic;Environmental adaptation;Endocrine system;Substance dependence;Nervous system;Nervous system	ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05034//Alcoholism;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04730//Long-term depression	K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534;K04534	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031821//G protein-coupled serotonin receptor binding;GO:0031852//mu-type opioid receptor binding;GO:0046872//metal ion binding;GO:0051430//corticotropin-releasing hormone receptor 1 binding	GO:0006457//protein folding;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway	--
ENSG00000087263	20.502	21.447	23.378	19.949	20.937	17.914	890	928	658	578	735	560.95	OGFOD1	2-oxoglutarate and iron dependent oxygenase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25585]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0031544//peptidyl-proline 3-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006449//regulation of translational termination;GO:0008283//cell population proliferation;GO:0018126//protein hydroxylation;GO:0019511//peptidyl-proline hydroxylation;GO:0034063//stress granule assembly	--
ENSG00000087266	8.877	10.613	9.127	8.898	9.062	9.997	706	840	528	546	555	565	SH3BP2	SH3 domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:10825]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07984	-	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0007165//signal transduction	--
ENSG00000087269	9.91	9.551	10.782	9.134	10.368	8.313	684	635	553	446	593	412	NOP14	NOP14 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:16821]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0030686//90S preribosome;GO:0030692//Noc4p-Nop14p complex;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0019899//enzyme binding;GO:0030515//snoRNA binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis"	--
ENSG00000087274	60.88	62.956	63.687	63.591	64.245	56.439	4816	4953	3689	3694	4283	3234	ADD1	adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0008290//F-actin capping protein complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016604//nuclear body	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0030507//spectrin binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0006884//cell volume homeostasis;GO:0020027//hemoglobin metabolic process;GO:0030036//actin cytoskeleton organization;GO:0030218//erythrocyte differentiation;GO:0032092//positive regulation of protein binding;GO:0035264//multicellular organism growth;GO:0048873//homeostasis of number of cells within a tissue;GO:0051016//barbed-end actin filament capping;GO:0051017//actin filament bundle assembly;GO:0071277//cellular response to calcium ion;GO:1903142//positive regulation of establishment of endothelial barrier;GO:1903393//positive regulation of adherens junction organization	--
ENSG00000087299	2.842	2.013	1.753	1.701	2.762	1.929	185.85	144.77	106.84	88.4	144.51	104.98	L2HGDH	L-2-hydroxyglutarate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:20499]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K00109;K00109	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0003973//(S)-2-hydroxy-acid oxidase activity;GO:0016491//oxidoreductase activity;GO:0047545//2-hydroxyglutarate dehydrogenase activity	GO:0006103//2-oxoglutarate metabolic process;GO:0044281//small molecule metabolic process	--
ENSG00000087301	4.01	3.937	3.653	2.714	3.331	3.417	379	374	255	190	266	235	TXNDC16	thioredoxin domain containing 16 [Source:HGNC Symbol;Acc:HGNC:19965]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000087302	50.499	44.321	45.561	37.843	39.46	47.331	1687.29	1538.08	1149.15	1022.83	1160.88	1072.35	RTRAF	"RNA transcription, translation and transport factor [Source:HGNC Symbol;Acc:HGNC:23169]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0072669//tRNA-splicing ligase complex;GO:0072686//mitotic spindle	GO:0000993//RNA polymerase II complex binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006469//negative regulation of protein kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050658//RNA transport"	--
ENSG00000087303	51.856	50.773	54.573	49.46	54.862	56.039	4700.71	4685.92	3669.85	3384.17	4128.12	3609.65	NID2	nidogen 2 [Source:HGNC Symbol;Acc:HGNC:13389]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0071711//basement membrane organization	--
ENSG00000087338	7.786	5.89	6.212	5.209	5.266	6.274	672	511	396	333	384	394	GMCL1	"germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843]"	-	-	-	-	GO:0005634//nucleus;GO:0016363//nuclear matrix	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000087365	74	82.293	82.87	79.824	76.922	70.889	4826	5217	3792	3637	4126	3251	SF3B2	splicing factor 3b subunit 2 [Source:HGNC Symbol;Acc:HGNC:10769]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12829	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000087448	8.213	7.615	5.685	5.744	6.426	6.425	839	816	513	438	584	527	KLHL42	kelch like family member 42 [Source:HGNC Symbol;Acc:HGNC:29252]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0032886//regulation of microtubule-based process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051301//cell division	--
ENSG00000087460	555.947	571.806	547.626	499.272	538.712	538.539	18475	19091	13404	12146	14895	12974	GNAS	GNAS complex locus [Source:HGNC Symbol;Acc:HGNC:4392]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Substance dependence;Infectious disease: parasitic;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Circulatory system;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Substance dependence;Cellular community - eukaryotes;Digestive system;Endocrine system;Digestive system;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Endocrine system;Nervous system;Endocrine system;Excretory system;Infectious disease: bacterial;Substance dependence;Excretory system	"ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko05146//Amoebiasis;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632;K04632	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030133//transport vesicle;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0010856//adenylate cyclase activator activity;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0031748//D1 dopamine receptor binding;GO:0031852//mu-type opioid receptor binding;GO:0035255//ionotropic glutamate receptor binding;GO:0046872//metal ion binding;GO:0051430//corticotropin-releasing hormone receptor 1 binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007565//female pregnancy;GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell;GO:0009306//protein secretion;GO:0009966//regulation of signal transduction;GO:0031279//regulation of cyclase activity;GO:0040015//negative regulation of multicellular organism growth;GO:0043547//positive regulation of GTPase activity;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0046907//intracellular transport;GO:0048589//developmental growth;GO:0050890//cognition;GO:0060348//bone development;GO:0060789//hair follicle placode formation;GO:0070527//platelet aggregation;GO:0071107//response to parathyroid hormone;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071870//cellular response to catecholamine stimulus;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000087470	14.822	12.03	11.491	8.93	10.91	9.994	1220	928	671	527	737	597	DNM1L	dynamin 1 like [Source:HGNC Symbol;Acc:HGNC:2973]	Organismal Systems;Cellular Processes;Environmental Information Processing	Immune system;Cell growth and death;Signal transduction	ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis;ko04668//TNF signaling pathway	K17065;K17065;K17065	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005903//brush border;GO:0005905//clathrin-coated pit;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0099073//mitochondrion-derived vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0000266//mitochondrial fission;GO:0001836//release of cytochrome c from mitochondria;GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0006816//calcium ion transport;GO:0006897//endocytosis;GO:0007005//mitochondrion organization;GO:0010468//regulation of gene expression;GO:0010821//regulation of mitochondrion organization;GO:0012501//programmed cell death;GO:0016559//peroxisome fission;GO:0043065//positive regulation of apoptotic process;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0048312//intracellular distribution of mitochondria;GO:0048511//rhythmic process;GO:0050714//positive regulation of protein secretion;GO:0051259//protein complex oligomerization;GO:0060047//heart contraction;GO:0061025//membrane fusion;GO:0065003//protein-containing complex assembly;GO:0070266//necroptotic process;GO:0070584//mitochondrion morphogenesis;GO:0070585//protein localization to mitochondrion;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090141//positive regulation of mitochondrial fission;GO:0090149//mitochondrial membrane fission;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1900063//regulation of peroxisome organization;GO:1903146//regulation of autophagy of mitochondrion;GO:1903578//regulation of ATP metabolic process;GO:1904666//regulation of ubiquitin protein ligase activity;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000087494	0.447	0.623	0.267	0.534	0.519	0.353	14	17	7	11	14	7	PTHLH	parathyroid hormone like hormone [Source:HGNC Symbol;Acc:HGNC:9607]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K22608	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0051428//peptide hormone receptor binding	GO:0001501//skeletal system development;GO:0002076//osteoblast development;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008544//epidermis development;GO:0010468//regulation of gene expression;GO:0030282//bone mineralization;GO:0032330//regulation of chondrocyte differentiation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0046058//cAMP metabolic process;GO:0061182//negative regulation of chondrocyte development	--
ENSG00000087495	0.061	0	0	0	0	0	2	0	0	0	0	0	PHACTR3	phosphatase and actin regulator 3 [Source:HGNC Symbol;Acc:HGNC:15833]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix	GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity	GO:0030036//actin cytoskeleton organization;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity	--
ENSG00000087502	25.913	21.322	18.428	21.686	21.01	15.39	817	703	433	414	546	415	ERGIC2	ERGIC and golgi 2 [Source:HGNC Symbol;Acc:HGNC:30208]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0016192//vesicle-mediated transport"	--
ENSG00000087510	0	0	0	0	0.06	0	0	0	0	0	3	0	TFAP2C	transcription factor AP-2 gamma [Source:HGNC Symbol;Acc:HGNC:11744]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0008584//male gonad development;GO:0040029//regulation of gene expression, epigenetic;GO:0042127//regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	AP-2
ENSG00000087586	2.011	1.996	1.699	1.825	1.416	1.3	83	71	55	50	51	41	AURKA	aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K11481;K11481	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031616//spindle pole centrosome;GO:0032133//chromosome passenger complex;GO:0042585//germinal vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043203//axon hillock;GO:0045120//pronucleus;GO:0048471//perinuclear region of cytoplasm;GO:0051233//spindle midzone;GO:0072686//mitotic spindle;GO:0072687//meiotic spindle;GO:0097431//mitotic spindle pole	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035174//histone serine kinase activity;GO:0046982//protein heterodimerization activity;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000212//meiotic spindle organization;GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007052//mitotic spindle organization;GO:0007057//spindle assembly involved in female meiosis I;GO:0007098//centrosome cycle;GO:0007100//mitotic centrosome separation;GO:0009611//response to wounding;GO:0009948//anterior/posterior axis specification;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030030//cell projection organization;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032465//regulation of cytokinesis;GO:0035404//histone-serine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0046605//regulation of centrosome cycle;GO:0046777//protein autophosphorylation;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051642//centrosome localization;GO:0071539//protein localization to centrosome;GO:0090141//positive regulation of mitochondrial fission;GO:0097421//liver regeneration;GO:1900195//positive regulation of oocyte maturation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1990138//neuron projection extension	--
ENSG00000087589	0.038	0.066	0.023	0.068	0	0.023	2	4	1	3	0	1	CASS4	Cas scaffold protein family member 4 [Source:HGNC Symbol;Acc:HGNC:15878]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:1990782//protein tyrosine kinase binding	GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0051897//positive regulation of protein kinase B signaling;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090527//actin filament reorganization;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000087842	8.802	11.601	11.986	12.483	10.53	14.831	239	312	241	248	237	290	PIR	pirin [Source:HGNC Symbol;Acc:HGNC:30048]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008127//quercetin 2,3-dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0007586//digestion;GO:0030099//myeloid cell differentiation;GO:0030224//monocyte differentiation"	--
ENSG00000087884	4.592	4.471	6.125	6.796	5.057	4.633	52	52	52	58	48	39	AAMDC	adipogenesis associated Mth938 domain containing [Source:HGNC Symbol;Acc:HGNC:30205]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0045600//positive regulation of fat cell differentiation	--
ENSG00000087903	3.423	2.917	2.257	4.37	2.943	2.498	207	204	100	150	173	121	RFX2	regulatory factor X2 [Source:HGNC Symbol;Acc:HGNC:9983]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001675//acrosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060271//cilium assembly;GO:1990830//cellular response to leukemia inhibitory factor"	RFX
ENSG00000087995	5.083	5.61	5.943	4.254	4.251	4.988	396.93	463.91	347.91	257.39	299.29	313.32	METTL2A	"methyltransferase 2A, methylcytidine [Source:HGNC Symbol;Acc:HGNC:25755]"	-	-	-	-	-	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016427//tRNA (cytosine) methyltransferase activity;GO:0016740//transferase activity;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000088002	0	0	0	0	0	0	0	0	0	0	0	0	SULT2B1	sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K01015;K01015	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0004027//alcohol sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0015485//cholesterol binding;GO:0016740//transferase activity;GO:0050294//steroid sulfotransferase activity;GO:1990239//steroid hormone binding	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation	--
ENSG00000088035	6.585	7.145	6.72	6.781	7.054	7.315	278	313	220	210	251	222	ALG6	"ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K03848;K03848	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004583//dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0042281//dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity;GO:0046527//glucosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006490//oligosaccharide-lipid intermediate biosynthetic process	--
ENSG00000088038	15.349	14.088	14.28	17.106	15.707	15.247	674	663	461.19	589.83	582	498.93	CNOT3	CCR4-NOT transcription complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7879]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12580	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex	GO:0005515//protein binding	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001829//trophectodermal cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006417//regulation of translation;GO:0031047//gene silencing by RNA;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2000036//regulation of stem cell population maintenance"	--
ENSG00000088053	0.022	0.043	0	0	0	0.03	1	2	0	0	0	1	GP6	glycoprotein VI platelet [Source:HGNC Symbol;Acc:HGNC:14388]	Organismal Systems;Environmental Information Processing	Immune system;Signaling molecules and interaction	ko04611//Platelet activation;ko04512//ECM-receptor interaction	K06264;K06264	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0097197//tetraspanin-enriched microdomain	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0038023//signaling receptor activity;GO:1990782//protein tyrosine kinase binding	GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030168//platelet activation;GO:0038065//collagen-activated signaling pathway;GO:1901731//positive regulation of platelet aggregation	--
ENSG00000088179	8.737	7.227	7.418	7.978	6.598	9.078	1302	882	679	579	701	726	PTPN4	protein tyrosine phosphatase non-receptor type 4 [Source:HGNC Symbol;Acc:HGNC:9656]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0035254//glutamate receptor binding	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000088205	8.003	6.454	7.01	5.5	5.672	6.568	623	505	403	299	373	372	DDX18	DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000088247	60.833	65.486	63.15	68.713	66.751	62.379	3843	4188	3051	3247	3641	2982	KHSRP	KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:HGNC:6316]	-	-	-	-	GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0010586//miRNA metabolic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0043488//regulation of mRNA stability;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0051028//mRNA transport;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0071345//cellular response to cytokine stimulus;GO:2000628//regulation of miRNA metabolic process"	Others
ENSG00000088256	20.205	18.396	22.2	23.021	21.273	21.649	1756	1607	1425	1482	1562	1369	GNA11	G protein subunit alpha 11 [Source:HGNC Symbol;Acc:HGNC:4379]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Signal transduction;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Endocrine system;Endocrine system;Nervous system	"ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04270//Vascular smooth muscle contraction;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression"	K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635;K04635	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	"GO:0001501//skeletal system development;GO:0001508//action potential;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007507//heart development;GO:0007603//phototransduction, visible light;GO:0008217//regulation of blood pressure;GO:0009649//entrainment of circadian clock;GO:0010259//multicellular organism aging;GO:0045634//regulation of melanocyte differentiation;GO:0048066//developmental pigmentation;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0071467//cellular response to pH;GO:0086100//endothelin receptor signaling pathway;GO:1904888//cranial skeletal system development"	--
ENSG00000088280	27.455	25.85	25.647	22.576	24.21	21.123	2005	2048	1404	1325	1593	1230	ASAP3	"ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:14987]"	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04144//Endocytosis;ko04666//Fc gamma R-mediated phagocytosis	K12488;K12488	GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0043231//intracellular membrane-bounded organelle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0016477//cell migration;GO:0043547//positive regulation of GTPase activity;GO:0051492//regulation of stress fiber assembly	--
ENSG00000088298	12.412	15.53	12.889	13.162	12.661	10.832	483	608	372	381	418	308	EDEM2	ER degradation enhancing alpha-mannosidase like protein 2 [Source:HGNC Symbol;Acc:HGNC:15877]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10085	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0044322//endoplasmic reticulum quality control compartment	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006986//response to unfolded protein;GO:0019082//viral protein processing;GO:0036509//trimming of terminal mannose on B branch;GO:0036510//trimming of terminal mannose on C branch;GO:0036511//trimming of first mannose on A branch;GO:0036512//trimming of second mannose on A branch;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway;GO:1904154//positive regulation of retrograde protein transport, ER to cytosol;GO:1904380//endoplasmic reticulum mannose trimming;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway"	--
ENSG00000088305	0.467	0.578	0.64	0.864	0.837	0.737	35	49	36	48	60	45	DNMT3B	DNA methyltransferase 3 beta [Source:HGNC Symbol;Acc:HGNC:2979]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko00270//Cysteine and methionine metabolism	K17399;K17399;K17399	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1902494//catalytic complex	"GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0051718//DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0032259//methylation;GO:0032776//DNA methylation on cytosine;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0090116//C-5 methylation of cytosine	--
ENSG00000088320	0.116	0	0.079	0.118	0.069	0.08	4	0	2	3	2	2	REM1	RRAD and GEM like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:15922]	-	-	-	-	GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005246//calcium channel regulator activity;GO:0005516//calmodulin binding;GO:0005525//GTP binding	GO:1901842//negative regulation of high voltage-gated calcium channel activity	--
ENSG00000088325	2.828	3.011	3.064	2.586	2.3	1.965	204	218	163	138	140	103	TPX2	TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005880//nuclear microtubule;GO:0015630//microtubule cytoskeleton;GO:0043203//axon hillock;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0061676//importin-alpha family protein binding	GO:0000278//mitotic cell cycle;GO:0006915//apoptotic process;GO:0007020//microtubule nucleation;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0032147//activation of protein kinase activity;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0090307//mitotic spindle assembly	--
ENSG00000088356	5.613	5.878	8.003	6.783	5.509	7.074	227.83	239.81	239.92	203.94	188.94	208.94	PDRG1	p53 and DNA damage regulated 1 [Source:HGNC Symbol;Acc:HGNC:16119]	-	-	-	-	GO:0005737//cytoplasm;GO:0016272//prefoldin complex;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0050821//protein stabilization	--
ENSG00000088367	26.067	24.555	29.87	21.315	28.07	29.277	1269	1169	924	798	1005	945	EPB41L1	erythrocyte membrane protein band 4.1 like 1 [Source:HGNC Symbol;Acc:HGNC:3378]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding	GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization	--
ENSG00000088386	0.139	0.107	0.104	0.042	0.055	0.042	9	7	5	2	3	2	SLC15A1	solute carrier family 15 member 1 [Source:HGNC Symbol;Acc:HGNC:10920]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14206	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0089717//spanning component of membrane	GO:0005427//proton-dependent oligopeptide secondary active transmembrane transporter activity;GO:0015293//symporter activity;GO:0015333//peptide:proton symporter activity;GO:0022857//transmembrane transporter activity;GO:0035673//oligopeptide transmembrane transporter activity;GO:0042937//tripeptide transmembrane transporter activity;GO:0071916//dipeptide transmembrane transporter activity	GO:0006811//ion transport;GO:0006857//oligopeptide transport;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0055085//transmembrane transport;GO:0140206//dipeptide import across plasma membrane;GO:0140207//tripeptide import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000088387	5.462	4.238	4.305	4.769	4.665	5.879	687	602	409	395	445	412	DOCK9	dedicator of cytokinesis 9 [Source:HGNC Symbol;Acc:HGNC:14132]	-	-	-	-	GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007264//small GTPase mediated signal transduction;GO:0008150//biological_process;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000088448	13.891	10.453	13.582	12.153	14.314	16.752	518	384	307	343	449	444	ANKRD10	ankyrin repeat domain 10 [Source:HGNC Symbol;Acc:HGNC:20265]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000088451	21.222	17.029	18.308	12.206	13.337	13.606	791	638	504	337	420	369	TGDS	"TDP-glucose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:20324]"	Metabolism;Metabolism	Global and overview maps;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko00523//Polyketide sugar unit biosynthesis	K01710;K01710	-	"GO:0005515//protein binding;GO:0008460//dTDP-glucose 4,6-dehydratase activity;GO:0016829//lyase activity"	GO:0009225//nucleotide-sugar metabolic process	--
ENSG00000088538	0.579	0.635	0.713	1.091	0.938	0.782	109	120	99	152	149	107	DOCK3	dedicator of cytokinesis 3 [Source:HGNC Symbol;Acc:HGNC:2989]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1903997//positive regulation of non-membrane spanning protein tyrosine kinase activity	--
ENSG00000088543	11.746	8.903	10.561	10.026	9.743	10.621	475	429	355	370	372	371	C3orf18	chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000088682	33.622	36.019	37.93	34.335	33.71	35.43	1107	1209	943	841	949	870	COQ9	coenzyme Q9 [Source:HGNC Symbol;Acc:HGNC:25302]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0110142//ubiquinone biosynthesis complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042803//protein homodimerization activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006744//ubiquinone biosynthetic process"	--
ENSG00000088726	0	0.031	0	0	0.074	0.135	0	1	0	0	2	2	TMEM40	transmembrane protein 40 [Source:HGNC Symbol;Acc:HGNC:25620]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000088727	2.934	3.658	2.674	2.461	3.089	3.57	75	71	40.09	37	49	58	KIF9	kinesin family member 9 [Source:HGNC Symbol;Acc:HGNC:16666]	-	-	-	-	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0031982//vesicle;GO:0036126//sperm flagellum	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	GO:0007018//microtubule-based movement;GO:0022617//extracellular matrix disassembly;GO:0071801//regulation of podosome assembly;GO:1901317//regulation of flagellated sperm motility;GO:1903008//organelle disassembly	--
ENSG00000088756	5.925	5.292	3.168	3.066	3.967	3.143	616	502	254	175	235	201	ARHGAP28	Rho GTPase activating protein 28 [Source:HGNC Symbol;Acc:HGNC:25509]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0030833//regulation of actin filament polymerization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:1904425//negative regulation of GTP binding	--
ENSG00000088766	23.358	19.466	23.059	22.252	21.305	24.852	915	775	608.58	773	808.61	783	CRLS1	cardiolipin synthase 1 [Source:HGNC Symbol;Acc:HGNC:16148]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K08744;K08744	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	"GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0008444//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity;GO:0008808//cardiolipin synthase activity;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0043337//CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity"	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0032049//cardiolipin biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0097068//response to thyroxine;GO:1905711//response to phosphatidylethanolamine	--
ENSG00000088782	0	0	0	0	0	0	0	0	0	0	0	0	DEFB127	defensin beta 127 [Source:HGNC Symbol;Acc:HGNC:16206]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000088808	26.988	27.963	29.132	24.223	27.58	31.012	2954.84	2971.7	2302.15	1986.52	2494.41	2449.72	PPP1R13B	protein phosphatase 1 regulatory subunit 13B [Source:HGNC Symbol;Acc:HGNC:14950]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008134//transcription factor binding	GO:0006915//apoptotic process;GO:0045786//negative regulation of cell cycle;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000088812	19.602	20.882	19.353	16.091	17.947	17.662	2479	2586	1800	1503	1922	1637	ATRN	attractin [Source:HGNC Symbol;Acc:HGNC:885]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0021549//cerebellum development;GO:0034446//substrate adhesion-dependent cell spreading;GO:0040014//regulation of multicellular organism growth;GO:0042552//myelination;GO:0043473//pigmentation	--
ENSG00000088826	24.996	26.606	25.299	23.4	25.454	17.357	1112	1179	830	773	956	562	SMOX	spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00410//beta-Alanine metabolism	K12259;K12259;K12259	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0016491//oxidoreductase activity;GO:0046592//polyamine oxidase activity;GO:0052894//norspermine:oxygen oxidoreductase activity;GO:0052895//N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity;GO:0052901//spermine:oxygen oxidoreductase (spermidine-forming) activity	GO:0006596//polyamine biosynthetic process;GO:0006598//polyamine catabolic process;GO:0006805//xenobiotic metabolic process;GO:0046208//spermine catabolic process	--
ENSG00000088827	0.173	0.241	0.356	0.15	0.213	0.038	25	35	38	16	24	4	SIGLEC1	sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06548	GO:0005576//extracellular region;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding;GO:0046790//virion binding	GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0075512//clathrin-dependent endocytosis of virus by host cell;GO:0098609//cell-cell adhesion	--
ENSG00000088832	85.616	89.972	89.092	95.541	93.804	97.448	2774	2939	2134	2286	2576	2284	FKBP1A	FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014802//terminal cisterna;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0031312//extrinsic component of organelle membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0098562//cytoplasmic side of membrane;GO:1990425//ryanodine receptor complex	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005527//macrolide binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0044325//transmembrane transporter binding;GO:0046332//SMAD binding;GO:0048185//activin binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0003007//heart morphogenesis;GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:0007183//SMAD protein complex assembly;GO:0022417//protein maturation by protein folding;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0032092//positive regulation of protein binding;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032880//regulation of protein localization;GO:0032925//regulation of activin receptor signaling pathway;GO:0042026//protein refolding;GO:0042110//T cell activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050776//regulation of immune response;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060347//heart trabecula formation;GO:0061077//chaperone-mediated protein folding;GO:0070588//calcium ion transmembrane transport;GO:0097435//supramolecular fiber organization;GO:1902991//regulation of amyloid precursor protein catabolic process;GO:1990000//amyloid fibril formation	--
ENSG00000088833	119.639	123.31	109.419	105.805	108.808	99.676	4212	4240	2899	2784	3224	2451	NSFL1C	NSFL1 cofactor [Source:HGNC Symbol;Acc:HGNC:15912]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14012	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:1990730//VCP-NSFL1C complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0043130//ubiquitin binding	GO:0000045//autophagosome assembly;GO:0000132//establishment of mitotic spindle orientation;GO:0007030//Golgi organization;GO:0031468//nuclear membrane reassembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0046604//positive regulation of mitotic centrosome separation;GO:0061025//membrane fusion;GO:1904780//negative regulation of protein localization to centrosome	--
ENSG00000088836	0.228	0.214	0.067	0.201	0.154	0.159	14	13	3	9	8	7	SLC4A11	solute carrier family 4 member 11 [Source:HGNC Symbol;Acc:HGNC:16438]	-	-	-	-	GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0005272//sodium channel activity;GO:0005372//water transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0015078//proton transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015252//proton channel activity;GO:0015293//symporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity;GO:0046715//active borate transmembrane transporter activity;GO:0046983//protein dimerization activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0006833//water transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0030003//cellular cation homeostasis;GO:0034599//cellular response to oxidative stress;GO:0035445//borate transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042044//fluid transport;GO:0046713//borate transport;GO:0050801//ion homeostasis;GO:0051881//regulation of mitochondrial membrane potential;GO:0055085//transmembrane transport;GO:0071476//cellular hypotonic response;GO:0098656//anion transmembrane transport;GO:1902600//proton transmembrane transport;GO:2000739//regulation of mesenchymal stem cell differentiation	--
ENSG00000088854	1.583	1.18	1.36	1.026	1.238	1.016	227	170	144	109	150	106	DNAAF9	dynein axonemal assembly factor 9 [Source:HGNC Symbol;Acc:HGNC:17721]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000088876	3.686	3.126	2.667	3.153	4.007	3.676	212	195.68	128.48	117	144.04	156	ZNF343	zinc finger protein 343 [Source:HGNC Symbol;Acc:HGNC:16017]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000088881	16.973	13.739	19.475	18.323	18.952	16.945	938	745	745	700	809	676	EBF4	EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	COE
ENSG00000088882	5.824	6.783	6.044	6.903	7.181	6.665	287	336	220	252	299	239	CPXM1	"carboxypeptidase X, M14 family member 1 [Source:HGNC Symbol;Acc:HGNC:15771]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0016485//protein processing	--
ENSG00000088888	8.241	8.994	8.75	9.137	9.415	9.244	2005	2198	1572	1646	1934	1636	MAVS	mitochondrial antiviral signaling protein [Source:HGNC Symbol;Acc:HGNC:29233]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12648;K12648;K12648;K12648;K12648;K12648;K12648;K12648;K12648;K12648	GO:0000151//ubiquitin ligase complex;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035591//signaling adaptor activity;GO:0050700//CARD domain binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0007165//signal transduction;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042307//positive regulation of protein import into nucleus;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060760//positive regulation of response to cytokine stimulus;GO:0071360//cellular response to exogenous dsRNA;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0071660//positive regulation of IP-10 production;GO:1900063//regulation of peroxisome organization	--
ENSG00000088899	1.999	1.698	1.587	2.311	2.088	2.753	174	152	102	149	155	176	LZTS3	leucine zipper tumor suppressor family member 3 [Source:HGNC Symbol;Acc:HGNC:30139]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	-	GO:0061001//regulation of dendritic spine morphogenesis	--
ENSG00000088926	0	0	0	0	0.037	0	0	0	0	0	2	0	F11	coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01323	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0070009//serine-type aminopeptidase activity	GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030193//regulation of blood coagulation;GO:0031639//plasminogen activation;GO:0051919//positive regulation of fibrinolysis	--
ENSG00000088930	29.566	27.163	27.141	23.968	22.136	23.701	2090	1930	1417	1255	1322	1219	XRN2	5'-3' exoribonuclease 2 [Source:HGNC Symbol;Acc:HGNC:12836]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03008//Ribosome biogenesis in eukaryotes;ko03018//RNA degradation	K12619;K12619	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016235//aggresome	GO:0000175//3'-5'-exoribonuclease activity;GO:0001147//transcription termination site sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004534//5'-3' exoribonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0000738//DNA catabolic process, exonucleolytic;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006353//DNA-templated transcription, termination;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006401//RNA catabolic process;GO:0007283//spermatogenesis;GO:0016070//RNA metabolic process;GO:0021766//hippocampus development;GO:0030182//neuron differentiation;GO:0060041//retina development in camera-type eye;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000088970	5.046	5.106	4.4	5.146	3.869	4.576	227	222	145	166	148	142	KIZ	kizuna centrosomal protein [Source:HGNC Symbol;Acc:HGNC:15865]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007051//spindle organization	--
ENSG00000088986	171.552	190.248	200.473	183.025	170.153	179.466	2376	2649	2053	1876	1993	1809	DYNLL1	dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Excretory system	ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10418;K10418	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0008180//COP9 signalosome;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030286//dynein complex;GO:0070821//tertiary granule membrane;GO:0072686//mitotic spindle;GO:0097542//ciliary tip;GO:0101003//ficolin-1-rich granule membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0006915//apoptotic process;GO:0007017//microtubule-based process;GO:0021762//substantia nigra development;GO:0042326//negative regulation of phosphorylation;GO:0060271//cilium assembly	--
ENSG00000088992	0	0.112	0	0	0.122	0	0	2	0	0	2	0	TESC	tescalcin [Source:HGNC Symbol;Acc:HGNC:26065]	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0000287//magnesium ion binding;GO:0004860//protein kinase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019212//phosphatase inhibitor activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030854//positive regulation of granulocyte differentiation;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0043086//negative regulation of catalytic activity;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0051604//protein maturation;GO:0071300//cellular response to retinoic acid;GO:0072659//protein localization to plasma membrane"	--
ENSG00000089006	39.043	36.164	36	35.15	33.89	34.234	1757	1612	1174	1118	1306	1073	SNX5	sorting nexin 5 [Source:HGNC Symbol;Acc:HGNC:14969]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17920	"GO:0001726//ruffle;GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030904//retromer complex;GO:0030905//retromer, tubulation complex;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031313//extrinsic component of endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070685//macropinocytic cup;GO:0097422//tubular endosome"	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0031748//D1 dopamine receptor binding;GO:0034452//dynactin binding;GO:0035091//phosphatidylinositol binding;GO:0045296//cadherin binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	"GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006907//pinocytosis;GO:0007174//epidermal growth factor catabolic process;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0016241//regulation of macroautophagy;GO:0035815//positive regulation of renal sodium excretion;GO:0042147//retrograde transport, endosome to Golgi;GO:0045776//negative regulation of blood pressure;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046628//positive regulation of insulin receptor signaling pathway"	--
ENSG00000089009	595.964	641.325	595.971	525.134	504.078	486.532	11411	12340	8419	7448	8153	6784	RPL6	ribosomal protein L6 [Source:HGNC Symbol;Acc:HGNC:10362]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02934;K02934	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042788//polysomal ribosome;GO:0043226//organelle;GO:0045202//synapse	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	"GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006355//regulation of transcription, DNA-templated;GO:0006412//translation"	--
ENSG00000089012	0	0	0	0	0	0	0	0	0	0	0	0	SIRPG	signal regulatory protein gamma [Source:HGNC Symbol;Acc:HGNC:15757]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K06551	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0022409//positive regulation of cell-cell adhesion;GO:0035556//intracellular signal transduction;GO:0050766//positive regulation of phagocytosis;GO:0050870//positive regulation of T cell activation	--
ENSG00000089022	10.738	13.057	12.575	10.791	9.861	13.955	561	579	412.07	364	441	422	MAPKAPK5	MAPK activated protein kinase 5 [Source:HGNC Symbol;Acc:HGNC:6889]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04442	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032007//negative regulation of TOR signaling;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:0051973//positive regulation of telomerase activity;GO:0090398//cellular senescence;GO:0090400//stress-induced premature senescence;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904355//positive regulation of telomere capping	--
ENSG00000089041	0.057	0	0.051	0.022	0.04	0.073	6	0	4	1	3	3	P2RX7	purinergic receptor P2X 7 [Source:HGNC Symbol;Acc:HGNC:8537]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04621//NOD-like receptor signaling pathway	K05220;K05220;K05220	GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031594//neuromuscular junction;GO:0032059//bleb;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0001530//lipopolysaccharide binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005102//signaling receptor binding;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015267//channel activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0000902//cell morphogenesis;GO:0001819//positive regulation of cytokine production;GO:0001845//phagolysosome assembly;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0001934//positive regulation of protein phosphorylation;GO:0002028//regulation of sodium ion transport;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006509//membrane protein ectodomain proteolysis;GO:0006649//phospholipid transfer to membrane;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0006884//cell volume homeostasis;GO:0006900//vesicle budding from membrane;GO:0006954//inflammatory response;GO:0007005//mitochondrion organization;GO:0007009//plasma membrane organization;GO:0007166//cell surface receptor signaling pathway;GO:0008219//cell death;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009617//response to bacterium;GO:0010033//response to organic substance;GO:0010043//response to zinc ion;GO:0010467//gene expression;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010628//positive regulation of gene expression;GO:0012501//programmed cell death;GO:0014049//positive regulation of glutamate secretion;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0014070//response to organic cyclic compound;GO:0016079//synaptic vesicle exocytosis;GO:0016485//protein processing;GO:0017121//plasma membrane phospholipid scrambling;GO:0019233//sensory perception of pain;GO:0030163//protein catabolic process;GO:0030501//positive regulation of bone mineralization;GO:0031668//cellular response to extracellular stimulus;GO:0032060//bleb assembly;GO:0032308//positive regulation of prostaglandin secretion;GO:0032496//response to lipopolysaccharide;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032963//collagen metabolic process;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0034405//response to fluid shear stress;GO:0034767//positive regulation of ion transmembrane transport;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0042098//T cell proliferation;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043132//NAD transport;GO:0043406//positive regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0045332//phospholipid translocation;GO:0045778//positive regulation of ossification;GO:0045779//negative regulation of bone resorption;GO:0045794//negative regulation of cell volume;GO:0045821//positive regulation of glycolytic process;GO:0046513//ceramide biosynthetic process;GO:0046931//pore complex assembly;GO:0048705//skeletal system morphogenesis;GO:0048873//homeostasis of number of cells within a tissue;GO:0050714//positive regulation of protein secretion;GO:0050830//defense response to Gram-positive bacterium;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051495//positive regulation of cytoskeleton organization;GO:0051592//response to calcium ion;GO:0051602//response to electrical stimulus;GO:0051709//regulation of killing of cells of other organism;GO:0051899//membrane depolarization;GO:0051901//positive regulation of mitochondrial depolarization;GO:0060079//excitatory postsynaptic potential;GO:0070230//positive regulation of lymphocyte apoptotic process;GO:0070588//calcium ion transmembrane transport;GO:0071318//cellular response to ATP;GO:0071359//cellular response to dsRNA;GO:0071407//cellular response to organic cyclic compound;GO:0072593//reactive oxygen species metabolic process;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0098655//cation transmembrane transport;GO:1904172//positive regulation of bleb assembly;GO:1905114//cell surface receptor signaling pathway involved in cell-cell signaling	--
ENSG00000089048	2.601	2.167	1.372	1.633	1.593	1.975	172	144	67	80	89	95	ESF1	ESF1 nucleolar pre-rRNA processing protein homolog [Source:HGNC Symbol;Acc:HGNC:15898]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003723//RNA binding	GO:0006364//rRNA processing	--
ENSG00000089050	7.853	7.838	7.678	5.352	6.712	6.328	626	628	452	316	452	367	RBBP9	"RB binding protein 9, serine hydrolase [Source:HGNC Symbol;Acc:HGNC:9892]"	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0042127//regulation of cell population proliferation	--
ENSG00000089053	39.454	39.196	38.05	38.091	38.979	37.155	1938	1972	1387	1399	1644	1345	ANAPC5	anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system;Immune system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko04657//IL-17 signaling pathway	K03352;K03352;K03352;K03352;K03352;K03352	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019903//protein phosphatase binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000089057	27.978	31.395	27.198	20.547	26.132	23.291	4035	4551	2897	2195	3184	2444	SLC23A2	solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0008520//L-ascorbate:sodium symporter activity;GO:0015229//L-ascorbic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006979//response to oxidative stress;GO:0015882//L-ascorbic acid transmembrane transport;GO:0019852//L-ascorbic acid metabolic process;GO:0055085//transmembrane transport;GO:0070904//transepithelial L-ascorbic acid transport;GO:0071361//cellular response to ethanol;GO:1901215//negative regulation of neuron death;GO:1903861//positive regulation of dendrite extension	--
ENSG00000089060	6.205	6.971	6.601	7.975	6.218	4.845	366	375	242	247	300	232	SLC8B1	solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030061//mitochondrial crista;GO:0032592//integral component of mitochondrial membrane	GO:0005432//calcium:sodium antiporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0042803//protein homodimerization activity;GO:0086038//calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0035725//sodium ion transmembrane transport;GO:0042593//glucose homeostasis;GO:0050796//regulation of insulin secretion;GO:0050896//response to stimulus;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051560//mitochondrial calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0099093//calcium export from the mitochondrion;GO:1901623//regulation of lymphocyte chemotaxis;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000089063	83.627	82.676	83.954	80.742	77.32	86.478	2634	2605	1947	1883	2058	1977	TMEM230	transmembrane protein 230 [Source:HGNC Symbol;Acc:HGNC:15876]	Human Diseases;Environmental Information Processing	Infectious disease: bacterial;Signal transduction	ko05132//Salmonella infection;ko04014//Ras signaling pathway	K17637;K17637	GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0048489//synaptic vesicle transport	--
ENSG00000089091	1.488	1.222	1.299	1.33	1.382	1.176	94	74	57	56	81	59	DZANK1	double zinc ribbon and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15858]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0042462//eye photoreceptor cell development	--
ENSG00000089094	5.895	7.366	6.97	6.77	6.724	6.813	473.95	592.81	463	373.93	503	389	KDM2B	lysine demethylase 2B [Source:HGNC Symbol;Acc:HGNC:13610]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0031519//PcG protein complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0019843//rRNA binding;GO:0032452//histone demethylase activity;GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140680//histone H3-di/monomethyl-lysine-36 demethylase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0007283//spermatogenesis;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0021592//fourth ventricle development;GO:0021670//lateral ventricle development;GO:0021678//third ventricle development;GO:0021993//initiation of neural tube closure;GO:0030307//positive regulation of cell growth;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0035518//histone H2A monoubiquitination;GO:0043524//negative regulation of neuron apoptotic process;GO:0048596//embryonic camera-type eye morphogenesis;GO:0070544//histone H3-K36 demethylation;GO:1902459//positive regulation of stem cell population maintenance;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000089101	0.273	0.846	0.195	0.549	0.115	0.03	13	26	9	6	5	1	CFAP61	cilia and flagella associated protein 61 [Source:HGNC Symbol;Acc:HGNC:15872]	-	-	-	-	GO:0001536//radial spoke stalk;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection	-	GO:0003341//cilium movement;GO:0044782//cilium organization	--
ENSG00000089116	0	0	0	0	0	0	0	0	0	0	0	0	LHX5	LIM homeobox 5 [Source:HGNC Symbol;Acc:HGNC:14216]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18493	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0021527//spinal cord association neuron differentiation;GO:0021549//cerebellum development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021766//hippocampus development;GO:0021846//cell proliferation in forebrain;GO:0021879//forebrain neuron differentiation;GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0030182//neuron differentiation;GO:0042127//regulation of cell population proliferation;GO:0045893//positive regulation of transcription, DNA-templated"	Homeobox
ENSG00000089123	3.417	2.335	2.481	2.195	3.208	3.413	166	114	89	79	110	107	TASP1	taspase 1 [Source:HGNC Symbol;Acc:HGNC:15859]	-	-	-	-	GO:0005737//cytoplasm	GO:0004298//threonine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	"GO:0006508//proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051604//protein maturation"	--
ENSG00000089127	0.07	0.428	0.142	0.726	0.218	0.244	2	13	3	19	6	6	OAS1	2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05160//Hepatitis C;ko05162//Measles	K14216;K14216;K14216;K14216;K14216;K14216;K14216	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006006//glucose metabolic process;GO:0009615//response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035457//cellular response to interferon-alpha;GO:0035458//cellular response to interferon-beta;GO:0042593//glucose homeostasis;GO:0042742//defense response to bacterium;GO:0043129//surfactant homeostasis;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051259//protein complex oligomerization;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0060700//regulation of ribonuclease activity;GO:0070106//interleukin-27-mediated signaling pathway;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0071659//negative regulation of IP-10 production;GO:0098586//cellular response to virus;GO:0140374//antiviral innate immune response;GO:1901857//positive regulation of cellular respiration;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000089154	17.972	18.83	21.438	18.302	20.095	19.914	3236	3408	2851	2441	3057	2609	GCN1	GCN1 activator of EIF2AK4 [Source:HGNC Symbol;Acc:HGNC:4199]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0016020//membrane	"GO:0003723//RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0043022//ribosome binding;GO:0045296//cadherin binding"	GO:0006412//translation;GO:0006417//regulation of translation;GO:0033674//positive regulation of kinase activity;GO:0034198//cellular response to amino acid starvation;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:1990253//cellular response to leucine starvation	--
ENSG00000089157	818.53	873.52	879.353	973.164	817.971	775.725	18426	19734	14620	16204	15539	12729	RPLP0	ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02941;K02941	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0070180//large ribosomal subunit rRNA binding	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0042254//ribosome biogenesis	--
ENSG00000089159	17.527	18.213	18.311	19.305	19.401	19.416	1328	1331	1041	1068	1178	1022	PXN	paxillin [Source:HGNC Symbol;Acc:HGNC:9718]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Infectious disease: bacterial;Signal transduction	ko05165//Human papillomavirus infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells;ko04370//VEGF signaling pathway	K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760;K05760	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0030054//cell junction	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0017166//vinculin binding;GO:0019903//protein phosphatase binding;GO:0038191//neuropilin binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007172//signal complex assembly;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034614//cellular response to reactive oxygen species;GO:0043542//endothelial cell migration;GO:0051496//positive regulation of stress fiber assembly;GO:0060396//growth hormone receptor signaling pathway"	--
ENSG00000089163	1.318	1.182	0.912	1.444	1.91	2.831	28	30	17	24	33	52	SIRT4	sirtuin 4 [Source:HGNC Symbol;Acc:HGNC:14932]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K11414;K11414	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019213//deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0046872//metal ion binding;GO:0047708//biotinidase activity;GO:0051287//NAD binding;GO:0061690//lipoamidase activity;GO:0070403//NAD+ binding	GO:0000820//regulation of glutamine family amino acid metabolic process;GO:0006471//protein ADP-ribosylation;GO:0006476//protein deacetylation;GO:0006541//glutamine metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007005//mitochondrion organization;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0034983//peptidyl-lysine deacetylation;GO:0046322//negative regulation of fatty acid oxidation;GO:0046676//negative regulation of insulin secretion;GO:0046889//positive regulation of lipid biosynthetic process;GO:0071456//cellular response to hypoxia;GO:0072350//tricarboxylic acid metabolic process;GO:1903217//negative regulation of protein processing involved in protein targeting to mitochondrion;GO:1904182//regulation of pyruvate dehydrogenase activity	--
ENSG00000089169	0	0	0	0	0	0	0	0	0	0	0	0	RPH3A	rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane	"GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0008430//selenium binding;GO:0031267//small GTPase binding;GO:0042301//phosphate ion binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:1901981//phosphatidylinositol phosphate binding"	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0061669//spontaneous neurotransmitter secretion	--
ENSG00000089177	2.463	2.399	2.199	1.706	1.763	2.748	232	239	165	131	141	146	KIF16B	kinesin family member 16B [Source:HGNC Symbol;Acc:HGNC:15869]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0031901//early endosome membrane	"GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0001704//formation of primary germ layer;GO:0001919//regulation of receptor recycling;GO:0006895//Golgi to endosome transport;GO:0007018//microtubule-based movement;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007492//endoderm development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0032801//receptor catabolic process;GO:0045022//early endosome to late endosome transport	--
ENSG00000089195	2.772	3.046	2.356	2.044	2.533	2.579	156	186	100	92	130	114	TRMT6	tRNA methyltransferase 6 non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:20900]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0080009//mRNA methylation	--
ENSG00000089199	0.059	0	0.135	0.106	0	0.054	3	0	4	4	0	2	CHGB	chromogranin B [Source:HGNC Symbol;Acc:HGNC:1930]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0030141//secretory granule	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000089220	257.094	257.455	276.025	281.176	274.677	281.989	7631	7681	6051	6182	6888	6090	PEBP1	phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0043409//negative regulation of MAPK cascade	--
ENSG00000089225	0.103	0.064	0.018	0	0.032	0.018	8	5	1	0	2	1	TBX5	T-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11604]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0001708//cell fate specification;GO:0002009//morphogenesis of an epithelium;GO:0003163//sinoatrial node development;GO:0003166//bundle of His development;GO:0003167//atrioventricular bundle cell differentiation;GO:0003181//atrioventricular valve morphogenesis;GO:0003197//endocardial cushion development;GO:0003218//cardiac left ventricle formation;GO:0003229//ventricular cardiac muscle tissue development;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0007389//pattern specification process;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030336//negative regulation of cell migration;GO:0035115//embryonic forelimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051891//positive regulation of cardioblast differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0060039//pericardium development;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0060413//atrial septum morphogenesis;GO:0060928//atrioventricular node cell development;GO:0060929//atrioventricular node cell fate commitment;GO:0060980//cell migration involved in coronary vasculogenesis;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0086054//bundle of His cell to Purkinje myocyte communication by electrical coupling;GO:1901846//positive regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1903598//positive regulation of gap junction assembly;GO:1903781//positive regulation of cardiac conduction"	T-box
ENSG00000089234	7.459	8.685	7.694	6.472	5.929	6.4	493	580	355	296	349	300	BRAP	BRCA1 associated protein [Source:HGNC Symbol;Acc:HGNC:1099]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K10632	GO:0000151//ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0003676//nucleic acid binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000165//MAPK cascade;GO:0007265//Ras protein signal transduction;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination	--
ENSG00000089248	120.346	123.546	127.114	124.761	113.437	122.001	4021	4138	3142	3079	3183	2950	ERP29	endoplasmic reticulum protein 29 [Source:HGNC Symbol;Acc:HGNC:13799]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09586	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005790//smooth endoplasmic reticulum;GO:0009986//cell surface;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0042470//melanosome	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0051087//chaperone binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006457//protein folding;GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0043335//protein unfolding;GO:0043406//positive regulation of MAP kinase activity;GO:0050709//negative regulation of protein secretion;GO:1902235//regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000089250	0	0	0.015	0	0	0	0	0	1	0	0	0	NOS1	nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Transport and catabolism;Signal transduction;Endocrine system;Environmental adaptation;Digestive system;Nervous system;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04145//Phagosome;ko04371//Apelin signaling pathway;ko04926//Relaxin signaling pathway;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04730//Long-term depression;ko00330//Arginine and proline metabolism;ko00220//Arginine biosynthesis	K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240;K13240	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery	GO:0004517//nitric-oxide synthase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0017080//sodium channel regulator activity;GO:0020037//heme binding;GO:0034617//tetrahydrobiopterin binding;GO:0034618//arginine binding;GO:0044325//transmembrane transporter binding;GO:0046870//cadmium ion binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0097110//scaffold protein binding	"GO:0001666//response to hypoxia;GO:0002028//regulation of sodium ion transport;GO:0006527//arginine catabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0006936//muscle contraction;GO:0006941//striated muscle contraction;GO:0007263//nitric oxide mediated signal transduction;GO:0007520//myoblast fusion;GO:0009408//response to heat;GO:0009725//response to hormone;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0031284//positive regulation of guanylate cyclase activity;GO:0032496//response to lipopolysaccharide;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033555//multicellular organismal response to stress;GO:0035066//positive regulation of histone acetylation;GO:0042136//neurotransmitter biosynthetic process;GO:0042178//xenobiotic catabolic process;GO:0042311//vasodilation;GO:0043267//negative regulation of potassium ion transport;GO:0044249//cellular biosynthetic process;GO:0045454//cell redox homeostasis;GO:0045776//negative regulation of blood pressure;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051346//negative regulation of hydrolase activity;GO:0051612//negative regulation of serotonin uptake;GO:0051926//negative regulation of calcium ion transport;GO:0055117//regulation of cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0071363//cellular response to growth factor stimulus;GO:0098735//positive regulation of the force of heart contraction;GO:0098924//retrograde trans-synaptic signaling by nitric oxide;GO:1902307//positive regulation of sodium ion transmembrane transport;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel"	--
ENSG00000089280	66.638	72.573	74.154	82.857	75.716	77.743	2518	2756	2069	2318	2416	2137	FUS	FUS RNA binding protein [Source:HGNC Symbol;Acc:HGNC:4010]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Transcription;Translation	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05202//Transcriptional misregulation in cancer;ko03040//Spliceosome;ko03015//mRNA surveillance pathway	K13098;K13098;K13098;K13098;K13098	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0043484//regulation of RNA splicing;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048255//mRNA stabilization;GO:0051260//protein homooligomerization;GO:1905168//positive regulation of double-strand break repair via homologous recombination"	--
ENSG00000089289	26.714	28.913	27.361	28.248	26.176	26.236	932	1017	705	730	777	666	IGBP1	immunoglobulin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:5461]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K17606;K17606	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0009966//regulation of signal transduction;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0034612//response to tumor necrosis factor;GO:0035303//regulation of dephosphorylation;GO:0042113//B cell activation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060632//regulation of microtubule-based movement;GO:0070555//response to interleukin-1	--
ENSG00000089327	4.906	5.6	2.088	7.137	5.844	4.283	90	104	29	98	93	58	FXYD5	FXYD domain containing ion transport regulator 5 [Source:HGNC Symbol;Acc:HGNC:4029]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0045296//cadherin binding;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0030033//microvillus assembly;GO:0043269//regulation of ion transport;GO:0046588//negative regulation of calcium-dependent cell-cell adhesion;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000089335	15.578	14.45	13.271	11.974	11.419	12.116	837	783	533	450	511	484	ZNF302	zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000089351	30.931	30.351	32.733	33.37	33.889	34.85	1676	1631	1273	1334	1537	1342	GRAMD1A	GRAM domain containing 1A [Source:HGNC Symbol;Acc:HGNC:29305]	-	-	-	-	GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0044232//organelle membrane contact site;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0120015//sterol transfer activity;GO:0120020//cholesterol transfer activity	GO:0006869//lipid transport;GO:0006914//autophagy;GO:0032366//intracellular sterol transport;GO:0071397//cellular response to cholesterol;GO:0120009//intermembrane lipid transfer	--
ENSG00000089356	5.308	4.147	5.06	9.914	7.059	8.854	139	112.75	97	170	142	145	FXYD3	FXYD domain containing ion transport regulator 3 [Source:HGNC Symbol;Acc:HGNC:4027]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006821//chloride transport;GO:0043269//regulation of ion transport;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000089472	17.2	16.301	17.177	13.729	14.749	14.271	1581	1514	1176	939	1121	968	HEPH	hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]	Organismal Systems;Metabolism	Digestive system;Metabolism of cofactors and vitamins	ko04978//Mineral absorption;ko00860//Porphyrin metabolism	K14735;K14735	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000089486	13.863	15.011	13.649	18.397	16.406	16.836	753	780	566	699	783	625	CDIP1	cell death inducing p53 target 1 [Source:HGNC Symbol;Acc:HGNC:13234]	-	-	-	-	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0098560//cytoplasmic side of late endosome membrane;GO:0098574//cytoplasmic side of lysosomal membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	zf-LITAF-like
ENSG00000089505	0.31	0.308	0.349	0.348	0.733	0.355	6	6	5	5	12	5	CMTM1	CKLF like MARVEL transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19172]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity	GO:0006935//chemotaxis;GO:0007165//signal transduction	--
ENSG00000089558	0	0	0	0	0	0	0	0	0	0	0	0	KCNH4	potassium voltage-gated channel subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:6253]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000089597	116.049	119.364	116.657	118.256	123.606	116.902	9013	9444	6669.19	6973	8145	6653	GANAB	glucosidase II alpha subunit [Source:HGNC Symbol;Acc:HGNC:4138]	Metabolism;Genetic Information Processing;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis	K05546;K05546;K05546	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017177//glucosidase II complex;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0033919//glucan 1,3-alpha-glucosidase activity;GO:0090599//alpha-glucosidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006491//N-glycan processing;GO:0008152//metabolic process	--
ENSG00000089639	3.998	4.586	4.013	4.338	3.782	4.426	237	270	185	170	214	173	GMIP	GEM interacting protein [Source:HGNC Symbol;Acc:HGNC:24852]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0034260//negative regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000089682	1.8	1.189	1.58	2.074	1.777	1.253	170	99	74	61	91	59	RBM41	RNA binding motif protein 41 [Source:HGNC Symbol;Acc:HGNC:25617]	-	-	-	-	GO:0005689//U12-type spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030626//U12 snRNA binding;GO:0097157//pre-mRNA intronic binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000089685	0.678	0.839	1.278	1.361	0.944	0.875	36	45	40	53	43	34	BIRC5	baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Cancer: overview;Infectious disease: viral;Signal transduction;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05161//Hepatitis B;ko04390//Hippo signaling pathway;ko04210//Apoptosis;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko04215//Apoptosis - multiple species	K08731;K08731;K08731;K08731;K08731;K08731;K08731;K08731	"GO:0000228//nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0032133//chromosome passenger complex;GO:1990713//survivin complex"	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0051087//chaperone binding	"GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007346//regulation of mitotic cell cycle;GO:0007605//sensory perception of sound;GO:0008284//positive regulation of cell population proliferation;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0031503//protein-containing complex localization;GO:0032268//regulation of cellular protein metabolic process;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0052548//regulation of endopeptidase activity;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1901970//positive regulation of mitotic sister chromatid separation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1903490//positive regulation of mitotic cytokinesis"	--
ENSG00000089692	0	0	0	0	0	0	0	0	0	0	0	0	LAG3	lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003823//antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042289//MHC class II protein binding	GO:0002250//adaptive immune response;GO:0002270//plasmacytoid dendritic cell activation;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0032703//negative regulation of interleukin-2 production;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050776//regulation of immune response;GO:0050868//negative regulation of T cell activation	--
ENSG00000089693	97.203	101.279	96.821	108.246	105.567	117.27	3131	3263	2278	2582	2865	2731	MLF2	myeloid leukemia factor 2 [Source:HGNC Symbol;Acc:HGNC:7126]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000089723	1.597	1.648	1.673	1.695	1.582	2.175	129.59	134.34	100.23	101.86	108.43	128.39	OTUB2	"OTU deubiquitinase, ubiquitin aldehyde binding 2 [Source:HGNC Symbol;Acc:HGNC:20351]"	-	-	-	-	GO:0005634//nucleus	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043130//ubiquitin binding	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:2000780//negative regulation of double-strand break repair	--
ENSG00000089737	57.898	61.072	57.657	50.202	55.859	54.478	3375.41	3542.66	2490.77	2186.14	2745.57	2309.61	DDX24	DEAD-box helicase 24 [Source:HGNC Symbol;Acc:HGNC:13266]	-	-	-	-	GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0016070//RNA metabolic process	--
ENSG00000089775	2.482	2.334	2.649	3.019	1.85	2.508	257.66	193.56	160.92	123	180.41	156.04	ZBTB25	zinc finger and BTB domain containing 25 [Source:HGNC Symbol;Acc:HGNC:13112]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000089818	11.432	12.722	13.44	12.277	10.214	13.95	562	596	436	422	471	437	NECAP1	NECAP endocytosis associated 1 [Source:HGNC Symbol;Acc:HGNC:24539]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030125//clathrin vesicle coat;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000089820	0.519	1.194	1.097	1.315	0.483	0.958	34	61	41	24	27	42	ARHGAP4	Rho GTPase activating protein 4 [Source:HGNC Symbol;Acc:HGNC:674]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0030426//growth cone	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0007399//nervous system development;GO:0010764//negative regulation of fibroblast migration;GO:0030336//negative regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000089847	0.378	0.871	0.748	0.62	0.673	0.781	26	62	37	36	46	36	ANKRD24	ankyrin repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:29424]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000089876	25.508	24.353	21.275	17.581	15.441	20.08	1227	1252.49	825.39	652	679.7	739.42	DHX32	DEAH-box helicase 32 (putative) [Source:HGNC Symbol;Acc:HGNC:16717]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000089902	7.52	7.189	8.116	7.026	6.37	7.051	897	862	715	508	642	612	RCOR1	REST corepressor 1 [Source:HGNC Symbol;Acc:HGNC:17441]	Human Diseases	Neurodegenerative disease	ko05016//Huntington disease	K11829	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0017053//transcription repressor complex;GO:1990391//DNA repair complex	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019899//enzyme binding	"GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010629//negative regulation of gene expression;GO:0016575//histone deacetylation;GO:0030218//erythrocyte differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070933//histone H4 deacetylation"	MYB
ENSG00000089916	18.645	14.935	14.173	8.528	10.972	9.815	1659	1454	1009	794	1016	850	GPATCH2L	G-patch domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:20210]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000090006	24.176	31.34	26.369	32.106	33.824	32.091	1183	1345	916	1290	1514	1177	LTBP4	latent transforming growth factor beta binding protein 4 [Source:HGNC Symbol;Acc:HGNC:6717]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0019838//growth factor binding;GO:0050431//transforming growth factor beta binding	GO:0001558//regulation of cell growth;GO:0006457//protein folding;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0046879//hormone secretion;GO:0048251//elastic fiber assembly	--
ENSG00000090013	36.205	40.431	42.166	50.537	44.547	48.778	600	673	517	620	625	591	BLVRB	biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism;ko00740//Riboflavin metabolism	K05901;K05901;K05901	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004074//biliverdin reductase (NAD(P)+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042602//riboflavin reductase (NADPH) activity;GO:0106276//biliberdin reductase NAD+ activity;GO:0106277//biliverdin reductase (NADP+) activity	GO:0042167//heme catabolic process	--
ENSG00000090020	15.142	16.424	16.536	18.6	17.989	16.995	1475	1622	1200	1349	1488	1205	SLC9A1	solute carrier family 9 member A1 [Source:HGNC Symbol;Acc:HGNC:11071]	Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cancer: overview;Circulatory system;Signal transduction;Endocrine system;Digestive system;Digestive system;Digestive system;Circulatory system;Digestive system	ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04971//Gastric acid secretion	K05742;K05742;K05742;K05742;K05742;K05742;K05742;K05742;K05742;K05742;K05742	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030315//T-tubule;GO:0042383//sarcolemma;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0090533//cation-transporting ATPase complex	"GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity;GO:0030346//protein phosphatase 2B binding;GO:0030674//protein-macromolecule adaptor activity;GO:0048306//calcium-dependent protein binding;GO:0060090//molecular adaptor activity;GO:0086040//sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential"	GO:0002026//regulation of the force of heart contraction;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0006885//regulation of pH;GO:0010447//response to acidic pH;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014070//response to organic cyclic compound;GO:0016477//cell migration;GO:0030011//maintenance of cell polarity;GO:0030154//cell differentiation;GO:0030307//positive regulation of cell growth;GO:0032869//cellular response to insulin stimulus;GO:0035725//sodium ion transmembrane transport;GO:0035794//positive regulation of mitochondrial membrane permeability;GO:0035994//response to muscle stretch;GO:0036376//sodium ion export across plasma membrane;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045760//positive regulation of action potential;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051259//protein complex oligomerization;GO:0051453//regulation of intracellular pH;GO:0051492//regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0051930//regulation of sensory perception of pain;GO:0055007//cardiac muscle cell differentiation;GO:0055085//transmembrane transport;GO:0070417//cellular response to cold;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0070997//neuron death;GO:0071236//cellular response to antibiotic;GO:0071257//cellular response to electrical stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071456//cellular response to hypoxia;GO:0071468//cellular response to acidic pH;GO:0071805//potassium ion transmembrane transport;GO:0071872//cellular response to epinephrine stimulus;GO:0086003//cardiac muscle cell contraction;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0086092//regulation of the force of heart contraction by cardiac conduction;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:0098735//positive regulation of the force of heart contraction;GO:1902533//positive regulation of intracellular signal transduction;GO:1902600//proton transmembrane transport;GO:1903281//positive regulation of calcium:sodium antiporter activity	--
ENSG00000090054	39.811	36.302	38.682	35.829	38.423	37.979	2138	2001	1542	1410	1708	1522	SPTLC1	serine palmitoyltransferase long chain base subunit 1 [Source:HGNC Symbol;Acc:HGNC:11277]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K00654;K00654;K00654	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex;GO:0035339//SPOTS complex	GO:0003824//catalytic activity;GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0009058//biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046511//sphinganine biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:1904504//positive regulation of lipophagy;GO:1904649//regulation of fat cell apoptotic process	--
ENSG00000090060	54.183	39.79	42.287	29.796	35.268	45.348	3928	3048	2307	1724	2237	2409	PAPOLA	poly(A) polymerase alpha [Source:HGNC Symbol;Acc:HGNC:14981]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14376	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0031123//RNA 3'-end processing;GO:0031124//mRNA 3'-end processing;GO:0031440//regulation of mRNA 3'-end processing;GO:0043631//RNA polyadenylation	--
ENSG00000090061	15.719	17.62	19.051	16.573	16.748	21.482	785.28	760.61	557.5	553.06	629.44	653.67	CCNK	cyclin K [Source:HGNC Symbol;Acc:HGNC:1596]	-	-	-	-	GO:0002944//cyclin K-CDK12 complex;GO:0002945//cyclin K-CDK13 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008024//cyclin/CDK positive transcription elongation factor complex	GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0009966//regulation of signal transduction;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0044828//negative regulation by host of viral genome replication;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:2001165//positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues"	--
ENSG00000090097	232.139	237.352	275.981	370.614	350.49	356.767	7684	8225	6564	8860	9565	8617	PCBP4	poly(rC) binding protein 4 [Source:HGNC Symbol;Acc:HGNC:8652]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding	"GO:0010468//regulation of gene expression;GO:0043488//regulation of mRNA stability;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0051252//regulation of RNA metabolic process"	--
ENSG00000090104	0	0	0	0	0	0	0	0	0	0	0	0	RGS1	regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005516//calmodulin binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009617//response to bacterium;GO:0009968//negative regulation of signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0061737//leukotriene signaling pathway	--
ENSG00000090238	37.431	35.626	39.573	32.204	32.006	30.436	712	686	560	461	513	428	YPEL3	yippee like 3 [Source:HGNC Symbol;Acc:HGNC:18327]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0046872//metal ion binding	GO:2000774//positive regulation of cellular senescence	--
ENSG00000090263	16.415	18.167	23.501	20.164	17.028	16.301	335	391	345	296	276	254	MRPS33	mitochondrial ribosomal protein S33 [Source:HGNC Symbol;Acc:HGNC:16634]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000090266	57.243	52.433	66.191	76.927	59.219	69.013	567.64	519.24	490.32	559.52	497.24	495.18	NDUFB2	NADH:ubiquinone oxidoreductase subunit B2 [Source:HGNC Symbol;Acc:HGNC:7697]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958;K03958	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000090273	48.124	49.174	51.409	50.038	48.658	43.625	1785	1826.85	1407	1370	1528	1172	NUDC	"nuclear distribution C, dynein complex regulator [Source:HGNC Symbol;Acc:HGNC:8045]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007080//mitotic metaphase plate congression;GO:0007097//nuclear migration;GO:0043434//response to peptide hormone;GO:0051301//cell division	--
ENSG00000090316	32.503	28.945	33.399	31.34	30.78	28.977	1423	1289	1093	1017	1171	929	MAEA	"macrophage erythroblast attacher, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:13731]"	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005826//actomyosin contractile ring;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0034657//GID complex;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043249//erythrocyte maturation;GO:0048821//erythrocyte development;GO:0048822//enucleate erythrocyte development;GO:0051301//cell division	--
ENSG00000090339	17.712	18.85	17.667	19.304	18.421	21.995	1090	1166	803	880	942	982	ICAM1	intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune disease;Signaling molecules and interaction;Cardiovascular disease;Cardiovascular disease;Immune system;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic	ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko05416//Viral myocarditis;ko04670//Leukocyte transendothelial migration;ko04668//TNF signaling pathway;ko05143//African trypanosomiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05144//Malaria	K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490;K06490	GO:0001772//immunological synapse;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001910//regulation of leukocyte mediated cytotoxicity;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0002457//T cell antigen processing and presentation;GO:0002693//positive regulation of cellular extravasation;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0022614//membrane to membrane docking;GO:0033627//cell adhesion mediated by integrin;GO:0044406//adhesion of symbiont to host;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0050900//leukocyte migration;GO:0061028//establishment of endothelial barrier;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0072683//T cell extravasation;GO:0098609//cell-cell adhesion;GO:1900027//regulation of ruffle assembly;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1904646//cellular response to amyloid-beta;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000090372	30.853	32.5	31.881	37.836	34.936	35.711	1956	1994	1556	1778	1907	1663	STRN4	striatin 4 [Source:HGNC Symbol;Acc:HGNC:15721]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K17608	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0090443//FAR/SIN/STRIPAK complex	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019904//protein domain specific binding;GO:0044877//protein-containing complex binding;GO:0051721//protein phosphatase 2A binding;GO:0070016//armadillo repeat domain binding	GO:0008150//biological_process	--
ENSG00000090376	0.029	0.03	0.039	0	0.041	0	5	5	5	0	6	0	IRAK3	interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K04732	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0001819//positive regulation of cytokine production;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0010933//positive regulation of macrophage tolerance induction;GO:0010936//negative regulation of macrophage cytokine production;GO:0019221//cytokine-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032494//response to peptidoglycan;GO:0032496//response to lipopolysaccharide;GO:0032695//negative regulation of interleukin-12 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0042177//negative regulation of protein catabolic process;GO:0043242//negative regulation of protein-containing complex disassembly;GO:0043244//regulation of protein-containing complex disassembly;GO:0043330//response to exogenous dsRNA;GO:0043407//negative regulation of MAP kinase activity;GO:0045824//negative regulation of innate immune response;GO:0046777//protein autophosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1	--
ENSG00000090382	0.097	0.032	0	0.044	0.804	0	3	1	0	1	21	0	LYZ	lysozyme [Source:HGNC Symbol;Acc:HGNC:6740]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13915	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	"GO:0003796//lysozyme activity;GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0042802//identical protein binding"	GO:0001895//retina homeostasis;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0019730//antimicrobial humoral response;GO:0019835//cytolysis;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000090402	0	0	0	0	0	0	0	0	0	0	0	0	SI	sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K01203;K01203;K01203;K01203	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0004574//oligo-1,6-glucosidase activity;GO:0004575//sucrose alpha-glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding"	GO:0005975//carbohydrate metabolic process;GO:0005987//sucrose catabolic process;GO:0008152//metabolic process;GO:0044245//polysaccharide digestion	--
ENSG00000090432	20.988	23.074	22.557	27.289	23.056	27.427	1057	1168	839	1018	981	1005	MUL1	mitochondrial E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:25762]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031307//integral component of mitochondrial outer membrane;GO:0043025//neuronal cell body	GO:0002039//p53 binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0000266//mitochondrial fission;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006996//organelle organization;GO:0010637//negative regulation of mitochondrial fusion;GO:0010821//regulation of mitochondrion organization;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0030308//negative regulation of cell growth;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0033235//positive regulation of protein sumoylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045824//negative regulation of innate immune response;GO:0050689//negative regulation of defense response to virus by host;GO:0050821//protein stabilization;GO:0051646//mitochondrion localization;GO:0051881//regulation of mitochondrial membrane potential;GO:0051898//negative regulation of protein kinase B signaling;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0071360//cellular response to exogenous dsRNA;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0090141//positive regulation of mitochondrial fission;GO:1901028//regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1903861//positive regulation of dendrite extension;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	--
ENSG00000090447	1.516	1.53	1.46	2.089	1.902	2.666	68	69	46	60	72	84	TFAP4	transcription factor AP-4 [Source:HGNC Symbol;Acc:HGNC:11745]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K09108	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0017053//transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0043065//positive regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043922//negative regulation by host of viral transcription;GO:0043923//positive regulation by host of viral transcription;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0065003//protein-containing complex assembly;GO:0071549//cellular response to dexamethasone stimulus;GO:1901990//regulation of mitotic cell cycle phase transition;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"	bHLH
ENSG00000090470	7.173	8.631	10.127	10.426	9.299	9.764	420	508	345	360	460	416	PDCD7	programmed cell death 7 [Source:HGNC Symbol;Acc:HGNC:8767]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005689//U12-type spliceosomal complex	-	GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0051384//response to glucocorticoid	--
ENSG00000090487	84.443	84.755	87.296	88.998	85.459	86.296	3073	3047	2321	2375	2613	2293	SPG21	"SPG21 abhydrolase domain containing, maspardin [Source:HGNC Symbol;Acc:HGNC:20373]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K19367	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042609//CD4 receptor binding	GO:0050851//antigen receptor-mediated signaling pathway	--
ENSG00000090512	0	0	0	0	0	0	0	0	0	0	0	0	FETUB	fetuin B [Source:HGNC Symbol;Acc:HGNC:3658]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0004857//enzyme inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0008150//biological_process;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000090520	47.348	48.238	42.187	45.399	43.729	43.715	1650.5	1720	1097.44	1194.34	1310.48	1110.1	DNAJB11	DnaJ heat shock protein family (Hsp40) member B11 [Source:HGNC Symbol;Acc:HGNC:14889]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09517	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0006457//protein folding;GO:0032781//positive regulation of ATPase activity;GO:0051604//protein maturation	--
ENSG00000090530	17	17.793	11.92	22.312	28.146	24.451	1119	1131	608	1147	1469	1152	P3H2	prolyl 3-hydroxylase 2 [Source:HGNC Symbol;Acc:HGNC:19317]	-	-	-	-	GO:0005604//basement membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0008285//negative regulation of cell population proliferation;GO:0019511//peptidyl-proline hydroxylation;GO:0032963//collagen metabolic process	--
ENSG00000090534	0	0	0.302	0	0	0.035	0	0	6	0	0	1	THPO	thrombopoietin [Source:HGNC Symbol;Acc:HGNC:11795]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K06854;K06854;K06854	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0032496//response to lipopolysaccharide;GO:0035855//megakaryocyte development;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0050896//response to stimulus;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0097696//receptor signaling pathway via STAT;GO:1902035//positive regulation of hematopoietic stem cell proliferation	--
ENSG00000090539	0.548	0.708	0.705	0.185	0.47	0.338	40	52	37	10	29	17	CHRD	chordin [Source:HGNC Symbol;Acc:HGNC:1949]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K04657	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0009790//embryo development;GO:0021919//BMP signaling pathway involved in spinal cord dorsal/ventral patterning;GO:0030336//negative regulation of cell migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0033504//floor plate development;GO:0045668//negative regulation of osteoblast differentiation;GO:0045785//positive regulation of cell adhesion	--
ENSG00000090554	0.321	0.462	0	0.312	0.337	0.385	7	10	0	5	6	6	FLT3LG	fms related receptor tyrosine kinase 3 ligand [Source:HGNC Symbol;Acc:HGNC:3766]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Immune system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04640//Hematopoietic cell lineage	K05454;K05454;K05454;K05454;K05454	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding	GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0035162//embryonic hemopoiesis	--
ENSG00000090565	12.615	11.469	11.988	11.503	12.021	12.531	977	888	677	667	820	653	RAB11FIP3	RAB11 family interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:17224]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12485	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051959//dynein light intermediate chain binding	GO:0007049//cell cycle;GO:0016192//vesicle-mediated transport;GO:0032456//endocytic recycling;GO:0032465//regulation of cytokinesis;GO:0051301//cell division;GO:0061512//protein localization to cilium;GO:0070164//negative regulation of adiponectin secretion	--
ENSG00000090581	48.295	54.489	53.018	57.678	50.379	52.78	1264.7	1386.82	1017.11	1067.62	1133.21	985.41	GNPTG	N-acetylglucosamine-1-phosphate transferase subunit gamma [Source:HGNC Symbol;Acc:HGNC:23026]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K10087	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0046835//carbohydrate phosphorylation	--
ENSG00000090612	6.919	4.512	3.533	4.555	4.539	4.082	498	326.02	205	198	277	222	ZNF268	zinc finger protein 268 [Source:HGNC Symbol;Acc:HGNC:13061]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007346//regulation of mitotic cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle"	zf-C2H2
ENSG00000090615	12.818	13.444	11.8	9.272	11.466	10.439	1583	1753	1240	938	1206	950	GOLGA3	golgin A3 [Source:HGNC Symbol;Acc:HGNC:4426]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0090498//extrinsic component of Golgi membrane	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007283//spermatogenesis	--
ENSG00000090621	31.882	32.554	32.018	31.976	32.477	31.557	1740	1843	1334	1391	1555	1200	PABPC4	poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0006412//translation;GO:0007596//blood coagulation;GO:0043488//regulation of mRNA stability;GO:0061515//myeloid cell development	--
ENSG00000090659	0	0	0	0	0	0	0	0	0	0	0	0	CD209	CD209 molecule [Source:HGNC Symbol;Acc:HGNC:1641]	Human Diseases;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Immune system	ko05152//Tuberculosis;ko04145//Phagosome;ko05162//Measles;ko04625//C-type lectin receptor signaling pathway	K06563;K06563;K06563;K06563	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043657//host cell	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0042605//peptide antigen binding;GO:0046790//virion binding;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006897//endocytosis;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0009988//cell-cell recognition;GO:0019062//virion attachment to host cell;GO:0019079//viral genome replication;GO:0019882//antigen processing and presentation;GO:0035556//intracellular signal transduction;GO:0042102//positive regulation of T cell proliferation;GO:0042129//regulation of T cell proliferation;GO:0045087//innate immune response;GO:0046718//viral entry into host cell;GO:0046968//peptide antigen transport;GO:0075733//intracellular transport of virus;GO:0097323//B cell adhesion;GO:1903902//positive regulation of viral life cycle	--
ENSG00000090661	87.736	86.786	101.639	108.37	102.651	116.032	2813	2757	2330	2525	2694	2685	CERS4	ceramide synthase 4 [Source:HGNC Symbol;Acc:HGNC:23747]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K24621;K24621;K24621	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000090674	15.033	14.645	15.575	15.55	14.358	18.113	640	613	470	489	510	566	MCOLN1	mucolipin TRP cation channel 1 [Source:HGNC Symbol;Acc:HGNC:13356]	Environmental Information Processing;Cellular Processes	Signal transduction;Transport and catabolism	ko04020//Calcium signaling pathway;ko04142//Lysosome	K04992;K04992	GO:0001891//phagocytic cup;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex	"GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005381//iron ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0097682//intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity;GO:0099604//ligand-gated calcium channel activity"	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0019722//calcium-mediated signaling;GO:0033572//transferrin transport;GO:0034220//ion transmembrane transport;GO:0034755//iron ion transmembrane transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071467//cellular response to pH;GO:0090382//phagosome maturation;GO:0097352//autophagosome maturation;GO:0098655//cation transmembrane transport	--
ENSG00000090686	23.196	19.482	19.676	15.166	17.485	16.75	1740	1569	1156	896	1105	932	USP48	ubiquitin specific peptidase 48 [Source:HGNC Symbol;Acc:HGNC:18533]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000090776	2.248	2.919	3.399	4.611	4.526	5.216	154	201	172	234	262	260	EFNB1	ephrin B1 [Source:HGNC Symbol;Acc:HGNC:3226]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05463	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0001755//neural crest cell migration;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0009880//embryonic pattern specification;GO:0030154//cell differentiation;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000090857	9.875	10.004	10.224	10.386	12.535	11.596	1689	1637	1244	1298	1613	1241	PDPR	pyruvate dehydrogenase phosphatase regulatory subunit [Source:HGNC Symbol;Acc:HGNC:30264]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045253//pyruvate dehydrogenase (lipoamide) phosphatase complex	GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006470//protein dephosphorylation;GO:1904184//positive regulation of pyruvate dehydrogenase activity	--
ENSG00000090861	60.791	63.104	63.403	62.39	63.316	74.465	4340	4531	3344	3301	3823	3874	AARS1	alanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:20]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01872	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0002196//Ser-tRNA(Ala) hydrolase activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004813//alanine-tRNA ligase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016597//amino acid binding;GO:0016874//ligase activity;GO:0045182//translation regulator activity;GO:0046872//metal ion binding;GO:0140101//catalytic activity, acting on a tRNA"	GO:0006399//tRNA metabolic process;GO:0006400//tRNA modification;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006419//alanyl-tRNA aminoacylation;GO:0008033//tRNA processing;GO:0021680//cerebellar Purkinje cell layer development;GO:0043039//tRNA aminoacylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0050885//neuromuscular process controlling balance;GO:0050905//neuromuscular process;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity;GO:0140018//regulation of cytoplasmic translational fidelity	--
ENSG00000090863	36.792	39.541	37.902	34.063	40.051	36.902	3756	3732	2536	2316	2924	2439	GLG1	golgi glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:4316]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06816	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0017134//fibroblast growth factor binding	GO:0010955//negative regulation of protein processing;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032330//regulation of chondrocyte differentiation;GO:0060349//bone morphogenesis	--
ENSG00000090889	0.209	0.186	0.223	0.267	0.221	0.272	19	17	15	18	17	18	KIF4A	kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030496//midbody;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding	GO:0000281//mitotic cytokinesis;GO:0006996//organelle organization;GO:0007018//microtubule-based movement;GO:0007052//mitotic spindle organization;GO:0008089//anterograde axonal transport;GO:0051256//mitotic spindle midzone assembly	--
ENSG00000090905	10.797	11.105	9.967	7.322	10.057	8.837	1479	1435	1011	808	1076	879	TNRC6A	trinucleotide repeat containing adaptor 6A [Source:HGNC Symbol;Acc:HGNC:11969]	-	-	-	-	GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0009267//cellular response to starvation;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	--
ENSG00000090924	6.642	7.41	7.9	7.606	8.625	8.219	594	674	510	436	562	497	PLEKHG2	pleckstrin homology and RhoGEF domain containing G2 [Source:HGNC Symbol;Acc:HGNC:29515]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0030833//regulation of actin filament polymerization;GO:0050790//regulation of catalytic activity	--
ENSG00000090932	0.12	0.131	0.14	0.097	0.155	0.033	5	6	5	3	6	1	DLL3	delta like canonical Notch ligand 3 [Source:HGNC Symbol;Acc:HGNC:2909]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06051;K06051;K06051;K06051;K06051;K06051	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005112//Notch binding;GO:0005509//calcium ion binding	GO:0001501//skeletal system development;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0007386//compartment pattern specification;GO:0009888//tissue development;GO:0030154//cell differentiation;GO:0048339//paraxial mesoderm development;GO:0050768//negative regulation of neurogenesis	--
ENSG00000090971	20.771	16.839	21.777	20.816	20.447	21.042	571	466	435	423	472	417	NAT14	N-acetyltransferase 14 (putative) [Source:HGNC Symbol;Acc:HGNC:28918]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	"GO:0006352//DNA-templated transcription, initiation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000090975	5.443	4.999	7.349	6.172	7.597	7.653	769	722	779	657	924	796	PITPNM2	phosphatidylinositol transfer protein membrane associated 2 [Source:HGNC Symbol;Acc:HGNC:21044]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transfer activity;GO:0030971//receptor tyrosine kinase binding;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	GO:0006661//phosphatidylinositol biosynthetic process;GO:0015914//phospholipid transport;GO:0048015//phosphatidylinositol-mediated signaling;GO:0120009//intermembrane lipid transfer	--
ENSG00000090989	9.399	7.01	6.62	5.424	6.22	6.946	673	502	349	285	375	361	EXOC1	exocyst complex component 1 [Source:HGNC Symbol;Acc:HGNC:30380]	-	-	-	-	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0090543//Flemming body;GO:0098592//cytoplasmic side of apical plasma membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding"	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050714//positive regulation of protein secretion;GO:0051607//defense response to virus;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000091009	4.657	3.575	3.47	2.49	2.829	2.924	631.49	487.17	347.54	250.05	324.13	288.45	RBM27	RNA binding motif protein 27 [Source:HGNC Symbol;Acc:HGNC:29243]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing	--
ENSG00000091010	0	0.093	0.025	0.025	0.044	0	0	5	1	1	2	0	POU4F3	POU class 4 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9220]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0021562//vestibulocochlear nerve development;GO:0030154//cell differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:0042472//inner ear morphogenesis;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048675//axon extension;GO:0048839//inner ear development;GO:0050885//neuromuscular process controlling balance;GO:0051402//neuron apoptotic process;GO:0060113//inner ear receptor cell differentiation"	Pou
ENSG00000091039	19.322	13.063	10.898	6.712	9.327	10.454	2047	1381	858	668	829	844	OSBPL8	oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0032541//cortical endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0140343//phosphatidylserine transfer activity	GO:0006869//lipid transport;GO:0010891//negative regulation of sequestering of triglyceride;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0030336//negative regulation of cell migration;GO:0032148//activation of protein kinase B activity;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0045444//fat cell differentiation;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0090204//protein localization to nuclear pore;GO:0120009//intermembrane lipid transfer	--
ENSG00000091073	5.709	4.473	4.854	5.073	5.728	4.68	222	218	167	184	211	151	DTX2	deltex E3 ubiquitin ligase 2 [Source:HGNC Symbol;Acc:HGNC:15973]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06058	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination	--
ENSG00000091106	0.014	0.035	0	0	0.017	0.059	1	1	0	0	1	3	NLRC4	NLR family CARD domain containing 4 [Source:HGNC Symbol;Acc:HGNC:16412]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05132//Salmonella infection;ko05131//Shigellosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko05134//Legionellosis	K12805;K12805;K12805;K12805;K12805	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0061702//inflammasome complex;GO:0072557//IPAF inflammasome complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0061133//endopeptidase activator activity;GO:0089720//caspase binding	GO:0002218//activation of innate immune response;GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response;GO:0010954//positive regulation of protein processing;GO:0016045//detection of bacterium;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042742//defense response to bacterium;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0046456//icosanoid biosynthetic process;GO:0050729//positive regulation of inflammatory response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization;GO:0070269//pyroptosis;GO:0097202//activation of cysteine-type endopeptidase activity	--
ENSG00000091127	1.233	1.787	1.154	1.108	1.655	1.313	90	129	60	60	98	66	PUS7	pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0019899//enzyme binding	GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0017148//negative regulation of translation;GO:0031119//tRNA pseudouridine synthesis;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1990481//mRNA pseudouridine synthesis;GO:2000380//regulation of mesoderm development	--
ENSG00000091128	0.016	0.016	0.107	0.011	0	0	2	2	8	1	0	0	LAMB4	laminin subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:6491]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06245;K06245;K06245;K06245;K06245;K06245;K06245;K06245	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016020//membrane;GO:0043256//laminin complex;GO:0071944//cell periphery	GO:0005201//extracellular matrix structural constituent	GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0070831//basement membrane assembly	--
ENSG00000091129	0.209	0.231	0.514	0.167	0.185	0.245	27	30	21	16	13	23	NRCAM	neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06756	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043194//axon initial segment;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099061//integral component of postsynaptic density membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0030506//ankyrin binding;GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0098632//cell-cell adhesion mediator activity	GO:0001525//angiogenesis;GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007416//synapse assembly;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0008104//protein localization;GO:0010975//regulation of neuron projection development;GO:0019227//neuronal action potential propagation;GO:0030516//regulation of axon extension;GO:0031290//retinal ganglion cell axon guidance;GO:0034113//heterotypic cell-cell adhesion;GO:0045162//clustering of voltage-gated sodium channels;GO:0045666//positive regulation of neuron differentiation;GO:0098609//cell-cell adhesion;GO:0099175//regulation of postsynapse organization	--
ENSG00000091136	97.721	93.56	85.424	52.955	64.756	62.306	10948	10338	6928	4471	6109	4971	LAMB1	laminin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6486]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K05636;K05636;K05636;K05636;K05636;K05636;K05636;K05636	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005606//laminin-1 complex;GO:0005607//laminin-2 complex;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0043256//laminin complex;GO:0043257//laminin-8 complex;GO:0043259//laminin-10 complex;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0021812//neuronal-glial interaction involved in cerebral cortex radial glia guided migration;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035987//endodermal cell differentiation;GO:0042476//odontogenesis;GO:0045785//positive regulation of cell adhesion;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051149//positive regulation of muscle cell differentiation;GO:0070831//basement membrane assembly;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000091137	0	0	0.014	0.022	0.012	0	0	0	1	1	1	0	SLC26A4	solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K14702	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015111//iodide transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0006811//ion transport;GO:0006885//regulation of pH;GO:0007605//sensory perception of sound;GO:0008272//sulfate transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0015705//iodide transport;GO:0019532//oxalate transport;GO:0032880//regulation of protein localization;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000091138	0	0	0	0	0	0	0	0	0	0	0	0	SLC26A3	solute carrier family 26 member 3 [Source:HGNC Symbol;Acc:HGNC:3018]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04978//Mineral absorption	K14078;K14078	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0097225//sperm midpiece	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0048240//sperm capacitation;GO:0051454//intracellular pH elevation;GO:0055085//transmembrane transport;GO:0060081//membrane hyperpolarization;GO:0071320//cellular response to cAMP;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000091140	27.677	25.276	26.817	25.013	23.932	29.793	1340	1239	953	858	961	1024	DLD	dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00380//Tryptophan metabolism;ko00260//Glycine, serine and threonine metabolism;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle)"	K00382;K00382;K00382;K00382;K00382;K00382;K00382;K00382;K00382;K00382;K00382	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005929//cilium;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0043159//acrosomal matrix;GO:0045252//oxoglutarate dehydrogenase complex;GO:0045254//pyruvate dehydrogenase complex	"GO:0000166//nucleotide binding;GO:0004148//dihydrolipoyl dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor;GO:0034604//pyruvate dehydrogenase (NAD+) activity;GO:0050660//flavin adenine dinucleotide binding"	"GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006508//proteolysis;GO:0007369//gastrulation;GO:0009083//branched-chain amino acid catabolic process;GO:0042391//regulation of membrane potential;GO:0045454//cell redox homeostasis;GO:0048240//sperm capacitation;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate;GO:0106077//histone succinylation"	--
ENSG00000091157	7.9	8.228	7.412	6.235	6.701	8.958	1182	1087	819	691	847	777.99	WDR7	WD repeat domain 7 [Source:HGNC Symbol;Acc:HGNC:13490]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K24738	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000091164	33.899	30.477	33.066	29.91	32.193	34.488	1245	1087	832	782	951	888.01	TXNL1	thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436]	-	-	-	-	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0015036//disulfide oxidoreductase activity	-	--
ENSG00000091181	0.119	0.009	0.069	0.123	0.06	0	6	1	3	7	2	0	IL5RA	interleukin 5 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6017]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05067;K05067;K05067;K05067	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004914//interleukin-5 receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032674//regulation of interleukin-5 production;GO:0038043//interleukin-5-mediated signaling pathway;GO:0070665//positive regulation of leukocyte proliferation;GO:0071310//cellular response to organic substance	--
ENSG00000091262	4.909	4.379	4.441	4.579	3.158	3.526	252	287	203	206	229	165	ABCC6	ATP binding cassette subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:57]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05669	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0022857//transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0007601//visual perception;GO:0009410//response to xenobiotic stimulus;GO:0010467//gene expression;GO:0015867//ATP transport;GO:0030505//inorganic diphosphate transport;GO:0030643//cellular phosphate ion homeostasis;GO:0032026//response to magnesium ion;GO:0046034//ATP metabolic process;GO:0050896//response to stimulus;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0071716//leukotriene transport;GO:0110148//biomineralization;GO:1904383//response to sodium phosphate	--
ENSG00000091317	33.822	30.429	33.357	29.798	28.177	29.053	2320	2098	1689.92	1514	1632.93	1450	CMTM6	CKLF like MARVEL transmembrane domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19177]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0055038//recycling endosome membrane	GO:0005515//protein binding	GO:0015031//protein transport;GO:0031647//regulation of protein stability;GO:0032456//endocytic recycling	--
ENSG00000091409	53.741	47.401	47.914	42.498	48.84	48.121	6287	5553	4164	3684	4817	4106	ITGA6	integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: parasitic;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485;K06485	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0031994//insulin-like growth factor I binding;GO:0038132//neuregulin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0007044//cell-substrate junction assembly;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0010668//ectodermal cell differentiation;GO:0010976//positive regulation of neuron projection development;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0031589//cell-substrate adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0035878//nail development;GO:0042327//positive regulation of phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0043589//skin morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050900//leukocyte migration;GO:0098609//cell-cell adhesion;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000091428	13.486	10.87	10.346	7.165	9.233	9.873	856	822	571	420	565	497	RAPGEF4	Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Immune system;Endocrine system	ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04670//Leukocyte transendothelial migration;ko04911//Insulin secretion	K04351;K04351;K04351;K04351;K04351;K04351	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse	GO:0000166//nucleotide binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030552//cAMP binding;GO:0031267//small GTPase binding	GO:0002250//adaptive immune response;GO:0006887//exocytosis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0046879//hormone secretion;GO:0050790//regulation of catalytic activity;GO:0098693//regulation of synaptic vesicle cycle	--
ENSG00000091436	20.003	17.617	16.3	13.345	14.339	13.623	2286	1948	1326	1051	1244	1026	MAP3K20	mitogen-activated protein kinase kinase kinase 20 [Source:HGNC Symbol;Acc:HGNC:17797]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04424	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000077//DNA damage checkpoint signaling;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0007254//JNK cascade;GO:0008219//cell death;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0038066//p38MAPK cascade;GO:0042733//embryonic digit morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0051403//stress-activated MAPK cascade;GO:0060173//limb development;GO:0071480//cellular response to gamma radiation;GO:1904291//positive regulation of mitotic DNA damage checkpoint	--
ENSG00000091482	1.689	1.301	1.254	1.103	1.354	1.198	31	24	17	15	21	16	SMPX	small muscle protein X-linked [Source:HGNC Symbol;Acc:HGNC:11122]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005927//muscle tendon junction;GO:0031430//M band;GO:0043034//costamere;GO:0043292//contractile fiber	-	GO:0006941//striated muscle contraction	--
ENSG00000091483	28.194	28.038	27.445	28.635	31.022	31.538	1052	1054	756	792	976	858	FH	fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700]	Metabolism;Human Diseases;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Endocrine and metabolic disease;Global and overview maps;Cancer: specific types;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04934//Cushing syndrome;ko01200//Carbon metabolism;ko05211//Renal cell carcinoma;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K01679;K01679;K01679;K01679;K01679;K01679;K01679	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0045239//tricarboxylic acid cycle enzyme complex;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004333//fumarate hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity	GO:0006099//tricarboxylic acid cycle;GO:0006106//fumarate metabolic process;GO:0006108//malate metabolic process;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0048873//homeostasis of number of cells within a tissue;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000091490	15.171	15.49	15.233	13.545	14.546	14.595	1321	1328	986	890	1057	923	SEL1L3	SEL1L family member 3 [Source:HGNC Symbol;Acc:HGNC:29108]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000091513	110.724	125.063	109.138	140.967	123.283	110.663	3838.24	4391.15	2756.26	3460.02	3664.14	2963.6	TF	transferrin [Source:HGNC Symbol;Acc:HGNC:11740]	Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Digestive system;Cell growth and death	ko04066//HIF-1 signaling pathway;ko04978//Mineral absorption;ko04216//Ferroptosis	K14736;K14736;K14736	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0034774//secretory granule lumen;GO:0045178//basal part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1990712//HFE-transferrin receptor complex	GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0034986//iron chaperone activity;GO:0046872//metal ion binding;GO:1990459//transferrin receptor binding	"GO:0001895//retina homeostasis;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0007015//actin filament organization;GO:0009617//response to bacterium;GO:0019731//antibacterial humoral response;GO:0030316//osteoclast differentiation;GO:0031647//regulation of protein stability;GO:0034756//regulation of iron ion transport;GO:0042327//positive regulation of phosphorylation;GO:0045780//positive regulation of bone resorption;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0055072//iron ion homeostasis;GO:0060395//SMAD protein signal transduction;GO:0070371//ERK1 and ERK2 cascade;GO:0071281//cellular response to iron ion;GO:2000147//positive regulation of cell motility"	--
ENSG00000091527	95.646	89.276	80.107	89.615	91.314	102.963	4938	4577	3141	3370	3927	3733	CDV3	CDV3 homolog [Source:HGNC Symbol;Acc:HGNC:26928]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000091536	1.209	1.183	0.772	0.264	1.234	0.229	70	73	37	23	62	25	MYO15A	myosin XVA [Source:HGNC Symbol;Acc:HGNC:7594]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0032421//stereocilium bundle;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0098858//actin-based cell projection	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0009416//response to light stimulus;GO:0030050//vesicle transport along actin filament;GO:0042472//inner ear morphogenesis	--
ENSG00000091542	31.327	30.675	29.329	25.848	29.679	29.897	2016	1999	1419	1225	1643	1414	ALKBH5	"alkB homolog 5, RNA demethylase [Source:HGNC Symbol;Acc:HGNC:25996]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0035515//oxidative RNA demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:1990931//mRNA N6-methyladenosine dioxygenase activity	GO:0001666//response to hypoxia;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0035553//oxidative single-stranded RNA demethylation;GO:0043488//regulation of mRNA stability	--
ENSG00000091583	0	0	0	0	0	0	0	0	0	0	0	0	APOH	apolipoprotein H [Source:HGNC Symbol;Acc:HGNC:616]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K17305	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031089//platelet dense granule lumen;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0060230//lipoprotein lipase activator activity	"GO:0001937//negative regulation of endothelial cell proliferation;GO:0006641//triglyceride metabolic process;GO:0007597//blood coagulation, intrinsic pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030193//regulation of blood coagulation;GO:0030194//positive regulation of blood coagulation;GO:0030195//negative regulation of blood coagulation;GO:0031639//plasminogen activation;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0034197//triglyceride transport;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0051917//regulation of fibrinolysis;GO:0051918//negative regulation of fibrinolysis"	--
ENSG00000091592	0.011	0.047	0.016	0	0	0	1	5	1	0	0	0	NLRP1	NLR family pyrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14374]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12798	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0061702//inflammasome complex;GO:0072558//NLRP1 inflammasome complex	GO:0000166//nucleotide binding;GO:0003690//double-stranded DNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0043621//protein self-association;GO:0140608//cysteine-type endopeptidase activator activity	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response;GO:0012501//programmed cell death;GO:0032495//response to muramyl dipeptide;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042742//defense response to bacterium;GO:0042981//regulation of apoptotic process;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0051260//protein homooligomerization;GO:0051402//neuron apoptotic process;GO:0051607//defense response to virus;GO:0070269//pyroptosis;GO:0097264//self proteolysis;GO:0140374//antiviral innate immune response;GO:1904784//NLRP1 inflammasome complex assembly	--
ENSG00000091622	0.334	0.302	0.228	0.45	0.452	0.2	49	45	25	49	56	21	PITPNM3	PITPNM family member 3 [Source:HGNC Symbol;Acc:HGNC:21043]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0042995//cell projection;GO:0044297//cell body	GO:0004620//phospholipase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transfer activity;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding	GO:0006661//phosphatidylinositol biosynthetic process;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000091640	31.338	32.09	32.882	35.988	30.972	31.626	658	684	511	561	552	484	SPAG7	sperm associated antigen 7 [Source:HGNC Symbol;Acc:HGNC:11216]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0005515//protein binding	-	--
ENSG00000091651	1.493	1.649	1.563	0.918	1.196	0.739	50	56	33	22	34	18	ORC6	origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02608	GO:0000808//origin recognition complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005829//cytosol;GO:0016020//membrane	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0051782//negative regulation of cell division	--
ENSG00000091656	4.356	3.701	2.45	1.68	2.703	2.378	1067	856	507	361	633	439	ZFHX4	zinc finger homeobox 4 [Source:HGNC Symbol;Acc:HGNC:30939]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000091664	0	0	0	0	0	0	0	0	0	0	0	0	SLC17A6	solute carrier family 17 member 6 [Source:HGNC Symbol;Acc:HGNC:16703]	Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Nervous system;Nervous system;Nervous system;Substance dependence	ko04723//Retrograde endocannabinoid signaling;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle;ko05033//Nicotine addiction	K12302;K12302;K12302;K12302	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse;GO:0060076//excitatory synapse	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	"GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0006836//neurotransmitter transport;GO:0015813//L-glutamate transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0050803//regulation of synapse structure or activity;GO:0055085//transmembrane transport;GO:0098700//neurotransmitter loading into synaptic vesicle;GO:1990384//hyaloid vascular plexus regression"	--
ENSG00000091704	0.142	0.485	0.2	0	0.12	0	4	14	4	0	2	0	CPA1	carboxypeptidase A1 [Source:HGNC Symbol;Acc:HGNC:2296]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K08779;K08779	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006691//leukotriene metabolic process	--
ENSG00000091732	6.672	7.185	7.446	6.452	6.986	6.774	255	281	215	186	226	192	ZC3HC1	zinc finger C3HC-type containing 1 [Source:HGNC Symbol;Acc:HGNC:29913]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0051301//cell division;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000091831	0.095	0.026	0.024	0.048	0.054	0.037	11	3	2	4	6	3	ESR1	estrogen receptor 1 [Source:HGNC Symbol;Acc:HGNC:3467]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Endocrine system;Endocrine system;Drug resistance: antineoplastic;Endocrine system;Excretory system	ko05200//Pathways in cancer;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko04915//Estrogen signaling pathway;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04917//Prolactin signaling pathway;ko04961//Endocrine and other factor-regulated calcium reabsorption	K08550;K08550;K08550;K08550;K08550;K08550;K08550;K08550;K08550	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0035327//transcriptionally active chromatin;GO:0097550//transcription preinitiation complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001093//TFIIB-class transcription factor binding;GO:0001221//transcription coregulator binding;GO:0001222//transcription corepressor binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0017025//TBP-class protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0030284//estrogen receptor activity;GO:0030331//estrogen receptor binding;GO:0034056//estrogen response element binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001547//antral ovarian follicle growth;GO:0002064//epithelial cell development;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008209//androgen metabolic process;GO:0008584//male gonad development;GO:0010629//negative regulation of gene expression;GO:0010863//positive regulation of phospholipase C activity;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030522//intracellular receptor signaling pathway;GO:0032355//response to estradiol;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043401//steroid hormone mediated signaling pathway;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043627//response to estrogen;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045899//positive regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0048863//stem cell differentiation;GO:0050727//regulation of inflammatory response;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060065//uterus development;GO:0060068//vagina development;GO:0060523//prostate epithelial cord elongation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060745//mammary gland branching involved in pregnancy;GO:0060749//mammary gland alveolus development;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0071168//protein localization to chromatin;GO:0071391//cellular response to estrogen stimulus;GO:0071392//cellular response to estradiol stimulus;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA"	ESR-like
ENSG00000091844	0.213	0.049	0.099	0.059	0.086	0.184	35	8	12	7	12	22	RGS17	regulator of G protein signaling 17 [Source:HGNC Symbol;Acc:HGNC:14088]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000091879	0	0	0	0	0	0	0	0	0	0	0	0	ANGPT2	angiopoietin 2 [Source:HGNC Symbol;Acc:HGNC:485]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04066//HIF-1 signaling pathway	K05466;K05466;K05466;K05466;K05466;K05466	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0042995//cell projection;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0007165//signal transduction;GO:0007281//germ cell development;GO:0009314//response to radiation;GO:0009612//response to mechanical stimulus;GO:0009749//response to glucose;GO:0010467//gene expression;GO:0010812//negative regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0031100//animal organ regeneration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0048014//Tie signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0050928//negative regulation of positive chemotaxis;GO:0060135//maternal process involved in female pregnancy;GO:0071363//cellular response to growth factor stimulus;GO:0072012//glomerulus vasculature development	--
ENSG00000091947	16.729	18.802	17.51	23.801	19.99	20.233	527	600	413	563	535	466	TMEM101	transmembrane protein 101 [Source:HGNC Symbol;Acc:HGNC:28653]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000091972	1.488	0.7	0.808	1.158	1.557	1.271	57	30	26	36	57	34	CD200	CD200 molecule [Source:HGNC Symbol;Acc:HGNC:7203]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044297//cell body	GO:0005515//protein binding;GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0140081//glycosylated region protein binding	GO:0002695//negative regulation of leukocyte activation;GO:0008285//negative regulation of cell population proliferation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0032793//positive regulation of CREB transcription factor activity;GO:0034113//heterotypic cell-cell adhesion;GO:0043031//negative regulation of macrophage activation;GO:0050776//regulation of immune response;GO:0071636//positive regulation of transforming growth factor beta production;GO:0098609//cell-cell adhesion;GO:0150072//positive regulation of arginase activity;GO:0150074//positive regulation of protein-glutamine gamma-glutamyltransferase activity;GO:0150077//regulation of neuroinflammatory response;GO:0150079//negative regulation of neuroinflammatory response;GO:1901215//negative regulation of neuron death;GO:1904465//negative regulation of matrix metallopeptidase secretion;GO:1905522//negative regulation of macrophage migration;GO:2000405//negative regulation of T cell migration	--
ENSG00000091986	55.979	56.52	36.883	37.267	44.255	47.541	5715	5614	2726	2702	3793	3394	CCDC80	coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005614//interstitial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0001968//fibronectin binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding	GO:0009617//response to bacterium;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization	--
ENSG00000092009	0	0	0	0	0	0	0	0	0	0	0	0	CMA1	chymase 1 [Source:HGNC Symbol;Acc:HGNC:2097]	Human Diseases;Organismal Systems	Cardiovascular disease;Endocrine system	ko05415//Diabetic cardiomyopathy;ko04614//Renin-angiotensin system	K01329;K01329	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042277//peptide binding	GO:0002003//angiotensin maturation;GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0022617//extracellular matrix disassembly;GO:0030901//midbrain development;GO:0034769//basement membrane disassembly;GO:0045766//positive regulation of angiogenesis;GO:0050727//regulation of inflammatory response;GO:0071333//cellular response to glucose stimulus;GO:0140447//cytokine precursor processing	--
ENSG00000092010	38.623	43.625	48.114	47.812	43.836	42.268	774	881	714	709	744	615	PSME1	proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568]	Organismal Systems;Genetic Information Processing	"Immune system;Folding, sorting and degradation"	ko04612//Antigen processing and presentation;ko03050//Proteasome	K06696;K06696	GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0061133//endopeptidase activator activity	GO:0010950//positive regulation of endopeptidase activity;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0061136//regulation of proteasomal protein catabolic process;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000092020	10.417	10.445	11.598	8.547	10.661	7.896	309.87	290.89	243	192	261	179	PPP2R3C	protein phosphatase 2 regulatory subunit B''gamma [Source:HGNC Symbol;Acc:HGNC:17485]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11583;K11583;K11583;K11583;K11583;K11583;K11583	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000226//microtubule cytoskeleton organization;GO:0001782//B cell homeostasis;GO:0002759//regulation of antimicrobial humoral response;GO:0030865//cortical cytoskeleton organization;GO:0032147//activation of protein kinase activity;GO:0035303//regulation of dephosphorylation;GO:0043029//T cell homeostasis;GO:0045579//positive regulation of B cell differentiation;GO:0048536//spleen development;GO:0050864//regulation of B cell activation;GO:0051900//regulation of mitochondrial depolarization	--
ENSG00000092036	7.662	9.11	9.488	9.194	8.452	8.837	229	248	208	186	183.46	180	HAUS4	HAUS augmin like complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:20163]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0051011//microtubule minus-end binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000092051	0	0	0	0	0.04	0.016	0	0	0	0	3	1	JPH4	junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030314//junctional membrane complex;GO:0043198//dendritic shaft;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0007612//learning;GO:0048167//regulation of synaptic plasticity;GO:0050885//neuromuscular process controlling balance;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060402//calcium ion transport into cytosol;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000092054	0.296	0.573	0.249	0.054	0.151	0.209	37	72	23	5	16	19	MYH7	myosin heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:7577]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Cardiovascular disease;Circulatory system;Cardiovascular disease;Endocrine system;Cardiovascular disease;Circulatory system	ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05416//Viral myocarditis;ko04919//Thyroid hormone signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K17751;K17751;K17751;K17751;K17751;K17751;K17751	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0032982//myosin filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0002026//regulation of the force of heart contraction;GO:0002027//regulation of heart rate;GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0006941//striated muscle contraction;GO:0007512//adult heart development;GO:0014728//regulation of the force of skeletal muscle contraction;GO:0014883//transition between fast and slow fiber;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030049//muscle filament sliding;GO:0031449//regulation of slow-twitch skeletal muscle fiber contraction;GO:0046034//ATP metabolic process;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000092067	0	0	0	0	0	0	0	0	0	0	0	0	CEBPE	CCAAT enhancer binding protein epsilon [Source:HGNC Symbol;Acc:HGNC:1836]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05221//Acute myeloid leukemia	K10051;K10051	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006909//phagocytosis;GO:0006952//defense response;GO:0010628//positive regulation of gene expression;GO:0030099//myeloid cell differentiation;GO:0030225//macrophage differentiation;GO:0030851//granulocyte differentiation;GO:0042742//defense response to bacterium;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071222//cellular response to lipopolysaccharide;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000092068	174.73	191.671	231.531	296.849	286.031	297.193	12949	14228	12542	16309	17897	15923	SLC7A8	solute carrier family 7 member 8 [Source:HGNC Symbol;Acc:HGNC:11066]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K13781	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane	GO:0005515//protein binding;GO:0015101//organic cation transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042605//peptide antigen binding	GO:0006865//amino acid transport;GO:0009636//response to toxic substance;GO:0015695//organic cation transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015816//glycine transport;GO:0015820//leucine transport;GO:0015827//tryptophan transport;GO:0015829//valine transport;GO:0035524//proline transmembrane transport;GO:0055065//metal ion homeostasis;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport;GO:0089718//amino acid import across plasma membrane;GO:0098713//leucine import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1901998//toxin transport;GO:1903801//L-leucine import across plasma membrane;GO:1904273//L-alanine import across plasma membrane	--
ENSG00000092094	4.416	5.468	6.537	4.809	5.282	8.395	181	205	174	146	174	168	OSGEP	O-sialoglycoprotein endopeptidase [Source:HGNC Symbol;Acc:HGNC:18028]	-	-	-	-	GO:0000408//EKC/KEOPS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016607//nuclear speck	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0046872//metal ion binding;GO:0061711//N(6)-L-threonylcarbamoyladenine synthase activity"	GO:0002949//tRNA threonylcarbamoyladenosine modification;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0070525//tRNA threonylcarbamoyladenosine metabolic process	--
ENSG00000092096	94.775	100.38	111.323	97.001	97.689	91.775	4688	4970	4062	3508	4055	3296	SLC22A17	solute carrier family 22 member 17 [Source:HGNC Symbol;Acc:HGNC:23095]	-	-	-	-	GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031301//integral component of organelle membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0015891//siderophore transport;GO:0055072//iron ion homeostasis;GO:0055085//transmembrane transport	--
ENSG00000092098	10.362	14.098	9.89	10.754	13.866	12.934	693.78	754.46	454.55	541.97	710.49	476.99	RNF31	ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031]	Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Immune system;Cell growth and death	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis	K11974;K11974;K11974	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0071797//LUBAC complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:1990450//linear polyubiquitin binding	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0023035//CD40 signaling pathway;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0097039//protein linear polyubiquitination;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1904417//positive regulation of xenophagy	--
ENSG00000092108	16.208	14.253	11.721	11.141	12.27	12.469	712	634	384	368	470	399	SCFD1	sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding	"GO:0000902//cell morphogenesis;GO:0001666//response to hypoxia;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009636//response to toxic substance;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0051223//regulation of protein transport;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:1901998//toxin transport;GO:1902902//negative regulation of autophagosome assembly"	--
ENSG00000092140	5.368	3.754	3.935	3.355	3.212	4.293	447	244	202	178	202	232	G2E3	G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0016567//protein ubiquitination	--
ENSG00000092148	27.596	21.775	20.967	15.16	17.143	18.503	5128	4051	2909	2066.89	2736.87	2473.92	HECTD1	HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157]	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001779//natural killer cell differentiation;GO:0001843//neural tube closure;GO:0001892//embryonic placenta development;GO:0003170//heart valve development;GO:0003281//ventricular septum development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035904//aorta development;GO:0048856//anatomical structure development;GO:0051865//protein autoubiquitination;GO:0060707//trophoblast giant cell differentiation;GO:0060708//spongiotrophoblast differentiation;GO:0070534//protein K63-linked ubiquitination;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000092199	211.16	219.3	219.631	191.445	186.167	204.802	6863	7027	5260	4628	5242	4823	HNRNPC	heterogeneous nuclear ribonucleoprotein C [Source:HGNC Symbol;Acc:HGNC:5035]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12884	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005697//telomerase holoenzyme complex;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0031492//nucleosomal DNA binding;GO:0042802//identical protein binding;GO:0070034//telomerase RNA binding;GO:1990247//N6-methyladenosine-containing RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0006338//chromatin remodeling;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0070935//3'-UTR-mediated mRNA stabilization"	--
ENSG00000092200	0	0.025	0.033	0	0	0	0	2	1	0	0	0	RPGRIP1	RPGR interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13436]	-	-	-	-	GO:0005929//cilium;GO:0005930//axoneme;GO:0032391//photoreceptor connecting cilium;GO:0035869//ciliary transition zone;GO:0042995//cell projection;GO:0097730//non-motile cilium;GO:0120206//photoreceptor distal connecting cilium	GO:0005515//protein binding	GO:0007601//visual perception;GO:0042462//eye photoreceptor cell development;GO:0046548//retinal rod cell development;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:0061351//neural precursor cell proliferation;GO:1905515//non-motile cilium assembly	--
ENSG00000092201	26.756	25.249	22.398	19.109	20.352	18.662	2434	2328	1510	1296	1581	1243	SUPT16H	"SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0035101//FACT complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding	"GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly;GO:0006366//transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0034724//DNA replication-independent nucleosome organization"	--
ENSG00000092203	20.473	20.375	19.112	23.726	22.413	21.935	1197.44	1157.37	865	792	950	908.24	TOX4	TOX high mobility group box family member 4 [Source:HGNC Symbol;Acc:HGNC:20161]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0072357//PTW/PP1 phosphatase complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	HMG
ENSG00000092208	5.24	5.375	6.052	5.213	4.377	5.421	121	101	89	74	69	82	GEMIN2	gem nuclear organelle associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10884]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies	GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000387//spliceosomal snRNP assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:1905215//negative regulation of RNA binding"	--
ENSG00000092295	1.111	1.131	1.798	3.457	2.8	3.969	40	50	46	95	80	93	TGM1	transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777]	-	-	-	-	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006464//cellular protein modification process;GO:0010838//positive regulation of keratinocyte proliferation;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization;GO:0043163//cell envelope organization;GO:0045787//positive regulation of cell cycle	--
ENSG00000092330	17.73	17.402	18.271	18.911	18.313	17.351	767	762	583	605	664	549	TINF2	TERF1 interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGNC:11824]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0010370//perinucleolar chromocenter;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0070187//shelterin complex"	GO:0005515//protein binding;GO:0042162//telomeric DNA binding	"GO:0010836//negative regulation of protein ADP-ribosylation;GO:0016233//telomere capping;GO:0032202//telomere assembly;GO:0032206//positive regulation of telomere maintenance;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070198//protein localization to chromosome, telomeric region;GO:1904356//regulation of telomere maintenance via telomere lengthening"	--
ENSG00000092345	0	0	0	0	0	0	0	0	0	0	0	0	DAZL	deleted in azoospermia like [Source:HGNC Symbol;Acc:HGNC:2685]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0006417//regulation of translation;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045727//positive regulation of translation;GO:0045948//positive regulation of translational initiation;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000092377	0.233	0.021	0.198	0.056	0	0	5	1	7	2	0	0	TBL1Y	transducin beta like 1 Y-linked [Source:HGNC Symbol;Acc:HGNC:18502]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04508	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000092421	0.254	0.776	0.879	0.508	0.563	0.535	20	40	26	20	38	27	SEMA6A	semaphorin 6A [Source:HGNC Symbol;Acc:HGNC:10738]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06842	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0009887//animal organ morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071526//semaphorin-plexin signaling pathway;GO:0106089//negative regulation of cell adhesion involved in sprouting angiogenesis;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1903671//negative regulation of sprouting angiogenesis;GO:2001224//positive regulation of neuron migration	--
ENSG00000092439	24.143	17.308	18.511	12.295	15.068	19.096	3647	2602.13	2089	1407	1919	2102	TRPM7	transient receptor potential cation channel subfamily M member 7 [Source:HGNC Symbol;Acc:HGNC:17994]	Organismal Systems;Cellular Processes;Cellular Processes;Organismal Systems	Immune system;Cell growth and death;Cell growth and death;Digestive system	ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko04978//Mineral absorption	K04982;K04982;K04982;K04982	GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017022//myosin binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0010961//cellular magnesium ion homeostasis;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0016340//calcium-dependent cell-matrix adhesion;GO:0030001//metal ion transport;GO:0031032//actomyosin structure organization;GO:0046777//protein autophosphorylation;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0070266//necroptotic process;GO:0070588//calcium ion transmembrane transport;GO:0072507//divalent inorganic cation homeostasis;GO:0098655//cation transmembrane transport	--
ENSG00000092445	5.003	5.388	4.788	9.494	6.327	6.658	468	493	343	499	500	477	TYRO3	TYRO3 protein tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12446]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043548//phosphatidylinositol 3-kinase binding	GO:0001779//natural killer cell differentiation;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021885//forebrain cell migration;GO:0030168//platelet activation;GO:0032940//secretion by cell;GO:0033674//positive regulation of kinase activity;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042698//ovulation cycle;GO:0043277//apoptotic cell clearance;GO:0043491//protein kinase B signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0045824//negative regulation of innate immune response;GO:0046718//viral entry into host cell;GO:0046777//protein autophosphorylation;GO:0050728//negative regulation of inflammatory response;GO:0051250//negative regulation of lymphocyte activation;GO:0060068//vagina development;GO:0070050//neuron cellular homeostasis;GO:0070527//platelet aggregation;GO:1903902//positive regulation of viral life cycle	--
ENSG00000092470	2.074	2.235	1.855	1.515	1.276	1.969	111	93	80	48	61	65	WDR76	WD repeat domain 76 [Source:HGNC Symbol;Acc:HGNC:25773]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0090734//site of DNA damage	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0006974//cellular response to DNA damage stimulus;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000092529	7.86	11.41	8.631	15.349	12.768	10.007	205.76	294.24	165.85	264	261.73	212.04	CAPN3	calpain 3 [Source:HGNC Symbol;Acc:HGNC:1480]	-	-	-	-	GO:0005622//intracellular anatomical structure;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030016//myofibril;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0032991//protein-containing complex	GO:0003824//catalytic activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008307//structural constituent of muscle;GO:0016787//hydrolase activity;GO:0031402//sodium ion binding;GO:0031432//titin binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0055103//ligase regulator activity;GO:0060090//molecular adaptor activity	"GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007517//muscle organ development;GO:0012501//programmed cell death;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0014850//response to muscle activity;GO:0030163//protein catabolic process;GO:0030239//myofibril assembly;GO:0031648//protein destabilization;GO:0033234//negative regulation of protein sumoylation;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045214//sarcomere organization;GO:0045661//regulation of myoblast differentiation;GO:0045862//positive regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046716//muscle cell cellular homeostasis;GO:0050790//regulation of catalytic activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051592//response to calcium ion;GO:0061061//muscle structure development;GO:0065003//protein-containing complex assembly;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0071277//cellular response to calcium ion;GO:0071472//cellular response to salt stress;GO:0072657//protein localization to membrane;GO:0097264//self proteolysis;GO:1990092//calcium-dependent self proteolysis"	--
ENSG00000092531	47.632	70.854	49.56	49.461	45.731	55.747	2040	1826	1486	1535.08	1641	1817	SNAP23	synaptosome associated protein 23 [Source:HGNC Symbol;Acc:HGNC:11131]	Organismal Systems;Genetic Information Processing	"Immune system;Folding, sorting and degradation"	ko04611//Platelet activation;ko04130//SNARE interactions in vesicular transport	K08508;K08508	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030670//phagocytic vesicle membrane;GO:0031201//SNARE complex;GO:0035579//specific granule membrane;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0098793//presynapse	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0002553//histamine secretion by mast cell;GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006903//vesicle targeting;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016082//synaptic vesicle priming;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0061025//membrane fusion	--
ENSG00000092607	0.048	0.018	0	0.024	0.033	0.038	4	1	0	1	2	2	TBX15	T-box transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11594]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090571//RNA polymerase II transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001708//cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis"	T-box
ENSG00000092621	91.847	93.656	104.156	96.755	92.83	123.487	3539	3565	2964	2759	2979	3448	PHGDH	phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism"	K00058;K00058;K00058;K00058;K00058	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004617//phosphoglycerate dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030060//L-malate dehydrogenase activity;GO:0051287//NAD binding"	GO:0006541//glutamine metabolic process;GO:0006544//glycine metabolic process;GO:0006563//L-serine metabolic process;GO:0006564//L-serine biosynthetic process;GO:0006566//threonine metabolic process;GO:0007420//brain development;GO:0008652//cellular amino acid biosynthetic process;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0010468//regulation of gene expression;GO:0019530//taurine metabolic process;GO:0021510//spinal cord development;GO:0021782//glial cell development;GO:0021915//neural tube development;GO:0022008//neurogenesis;GO:0022900//electron transport chain;GO:0031175//neuron projection development;GO:0070314//G1 to G0 transition	--
ENSG00000092758	62.362	63.831	71.604	58.465	59.144	68.808	3229.91	3323	2739	2243	2588	2593	COL9A3	collagen type IX alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2219]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K08131;K08131;K08131;K08131;K08131	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005594//collagen type IX trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0030198//extracellular matrix organization	--
ENSG00000092820	292.751	300.318	315.77	230.217	260.389	279.032	18600	19184	14813	10837	13969	12893	EZR	ezrin [Source:HGNC Symbol;Acc:HGNC:12691]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Cell motility;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Digestive system	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04530//Tight junction;ko05206//MicroRNAs in cancer;ko04670//Leukocyte transendothelial migration;ko04971//Gastric acid secretion	K08007;K08007;K08007;K08007;K08007;K08007;K08007	GO:0001650//fibrillar center;GO:0001726//ruffle;GO:0001772//immunological synapse;GO:0001931//uropod;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0030175//filopodium;GO:0030863//cortical cytoskeleton;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0044853//plasma membrane raft;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098592//cytoplasmic side of apical plasma membrane	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0051015//actin filament binding;GO:0051018//protein kinase A binding;GO:0051117//ATPase binding;GO:0097718//disordered domain specific binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001951//intestinal D-glucose absorption;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0007159//leukocyte cell-cell adhesion;GO:0008360//regulation of cell shape;GO:0010628//positive regulation of gene expression;GO:0010737//protein kinase A signaling;GO:0022614//membrane to membrane docking;GO:0030033//microvillus assembly;GO:0030953//astral microtubule organization;GO:0031503//protein-containing complex localization;GO:0031532//actin cytoskeleton reorganization;GO:0031623//receptor internalization;GO:0032532//regulation of microvillus length;GO:0032703//negative regulation of interleukin-2 production;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0040018//positive regulation of multicellular organism growth;GO:0043622//cortical microtubule organization;GO:0046847//filopodium assembly;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050714//positive regulation of protein secretion;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051017//actin filament bundle assembly;GO:0051660//establishment of centrosome localization;GO:0061028//establishment of endothelial barrier;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:0072659//protein localization to plasma membrane;GO:0072697//protein localization to cell cortex;GO:1902115//regulation of organelle assembly;GO:1902896//terminal web assembly;GO:1902966//positive regulation of protein localization to early endosome;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903364//positive regulation of cellular protein catabolic process;GO:1903753//negative regulation of p38MAPK cascade;GO:2000643//positive regulation of early endosome to late endosome transport	--
ENSG00000092841	539.858	591.496	586.177	556.725	444.512	495.692	7428.58	8215	5959.18	5668	5167	4950	MYL6	myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587]	Cellular Processes;Organismal Systems;Organismal Systems	Cellular community - eukaryotes;Endocrine system;Circulatory system	ko04530//Tight junction;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction	K12751;K12751;K12751	GO:0005829//cytosol;GO:0005903//brush border;GO:0016020//membrane;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0016461//unconventional myosin complex;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0003774//cytoskeletal motor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0006936//muscle contraction;GO:0007519//skeletal muscle tissue development;GO:0030049//muscle filament sliding	--
ENSG00000092847	9.058	9.224	8.466	7.003	8.577	7.938	1629	1666	1147	908	1144	1049	AGO1	argonaute RISC component 1 [Source:HGNC Symbol;Acc:HGNC:3262]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K11593	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070578//RISC-loading complex;GO:1990904//ribonucleoprotein complex	GO:0000993//RNA polymerase II complex binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0061980//regulatory RNA binding	GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006417//regulation of translation;GO:0010501//RNA secondary structure unwinding;GO:0016246//RNA interference;GO:0016525//negative regulation of angiogenesis;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000092850	1.987	2.447	2.902	0.874	0.677	1.143	60	76	64	20	18	26	TEKT2	tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0042995//cell projection	-	GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility;GO:0036159//inner dynein arm assembly;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility	--
ENSG00000092853	0.241	0.167	0.263	0.05	0.117	0.034	26	14	16	5	11	3	CLSPN	claspin [Source:HGNC Symbol;Acc:HGNC:19715]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus	GO:0000217//DNA secondary structure binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0010997//anaphase-promoting complex binding	GO:0000076//DNA replication checkpoint signaling;GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0018105//peptidyl-serine phosphorylation;GO:0032147//activation of protein kinase activity;GO:0033314//mitotic DNA replication checkpoint signaling	--
ENSG00000092871	7.3	6.671	5.427	5.759	6.153	6.672	393.84	367.96	289.86	246.41	293.59	341.48	RFFL	ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0055038//recycling endosome membrane	GO:0002020//protease binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0010762//regulation of fibroblast migration;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0032006//regulation of TOR signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	--
ENSG00000092929	48.649	54.865	39.179	32.417	34.497	29.877	3696	4214	2126	1924	2233	1626	UNC13D	unc-13 homolog D [Source:HGNC Symbol;Acc:HGNC:23147]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0033093//Weibel-Palade body;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:0070382//exocytic vesicle	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0002432//granuloma formation;GO:0002467//germinal center formation;GO:0006887//exocytosis;GO:0006909//phagocytosis;GO:0043304//regulation of mast cell degranulation;GO:0043320//natural killer cell degranulation;GO:0045921//positive regulation of exocytosis;GO:0051607//defense response to virus;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1903307//positive regulation of regulated secretory pathway	--
ENSG00000092931	5.021	3.435	4.85	5.922	4.227	5.693	183.44	145.58	136.47	150.71	158.62	162.41	MFSD11	major facilitator superfamily domain containing 11 [Source:HGNC Symbol;Acc:HGNC:25458]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000092964	10.248	9.589	9.104	10.676	11.825	11.06	982	891	644	759	957	755	DPYSL2	dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07528	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	"GO:0004157//dihydropyrimidinase activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0019901//protein kinase binding;GO:0042802//identical protein binding"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0010975//regulation of neuron projection development;GO:0030154//cell differentiation;GO:0030516//regulation of axon extension;GO:0045664//regulation of neuron differentiation	--
ENSG00000092969	18.873	15.646	12.73	9.582	10.984	13.75	2217	1879	1090	840	1076	1179	TGFB2	transforming growth factor beta 2 [Source:HGNC Symbol;Acc:HGNC:11768]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: parasitic;Cancer: overview;Cancer: specific types;Cardiovascular disease;Infectious disease: viral;Immune disease;Cell growth and death;Signal transduction;Cancer: specific types;Infectious disease: parasitic;Signal transduction;Cell growth and death;Development and regeneration;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cardiovascular disease;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune disease;Infectious disease: parasitic	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05414//Dilated cardiomyopathy;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko05140//Leishmaniasis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04380//Osteoclast differentiation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05410//Hypertrophic cardiomyopathy;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05321//Inflammatory bowel disease;ko05144//Malaria	K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376;K13376	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030424//axon;GO:0031093//platelet alpha granule lumen;GO:0043025//neuronal cell body;GO:0062023//collagen-containing extracellular matrix	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0034714//type III transforming growth factor beta receptor binding;GO:0042803//protein homodimerization activity	GO:0000902//cell morphogenesis;GO:0001501//skeletal system development;GO:0001654//eye development;GO:0001666//response to hypoxia;GO:0001822//kidney development;GO:0001837//epithelial to mesenchymal transition;GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003149//membranous septum morphogenesis;GO:0003179//heart valve morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003274//endocardial cushion fusion;GO:0003289//atrial septum primum morphogenesis;GO:0003407//neural retina development;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007435//salivary gland morphogenesis;GO:0007507//heart development;GO:0008219//cell death;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008347//glial cell migration;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009792//embryo development ending in birth or egg hatching;GO:0010002//cardioblast differentiation;GO:0010629//negative regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010936//negative regulation of macrophage cytokine production;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030097//hemopoiesis;GO:0030199//collagen fibril organization;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0031069//hair follicle morphogenesis;GO:0032147//activation of protein kinase activity;GO:0032570//response to progesterone;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0032909//regulation of transforming growth factor beta2 production;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035910//ascending aorta morphogenesis;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042416//dopamine biosynthetic process;GO:0042476//odontogenesis;GO:0042704//uterine wall breakdown;GO:0043525//positive regulation of neuron apoptotic process;GO:0045216//cell-cell junction organization;GO:0045726//positive regulation of integrin biosynthetic process;GO:0045747//positive regulation of Notch signaling pathway;GO:0045778//positive regulation of ossification;GO:0045787//positive regulation of cell cycle;GO:0045823//positive regulation of heart contraction;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048103//somatic stem cell division;GO:0048566//embryonic digestive tract development;GO:0048666//neuron development;GO:0048699//generation of neurons;GO:0048839//inner ear development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050778//positive regulation of immune response;GO:0051781//positive regulation of cell division;GO:0051794//regulation of timing of catagen;GO:0051795//positive regulation of timing of catagen;GO:0051891//positive regulation of cardioblast differentiation;GO:0060038//cardiac muscle cell proliferation;GO:0060065//uterus development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0061626//pharyngeal arch artery morphogenesis;GO:0062009//secondary palate development;GO:0097191//extrinsic apoptotic signaling pathway;GO:1902256//regulation of apoptotic process involved in outflow tract morphogenesis;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903701//substantia propria of cornea development;GO:1904888//cranial skeletal system development;GO:1905006//negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	--
ENSG00000092978	2.76	2.902	2.016	2.14	1.759	2.555	240	238	127	129	129	145	GPATCH2	G-patch domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25499]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0005515//protein binding	-	--
ENSG00000093000	9.7	9.987	7.963	5.572	8.439	7.442	920	869	537	441	578	467	NUP50	nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14295;K14295	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding	GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0046907//intracellular transport;GO:0051028//mRNA transport	--
ENSG00000093009	0.142	0.177	0.347	0.416	0.542	0.157	5	4	9	12	11	4	CDC45	cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06628	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0031261//DNA replication preinitiation complex;GO:0036064//ciliary basal body;GO:0071162//CMG complex	GO:0003682//chromatin binding;GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0000076//DNA replication checkpoint signaling;GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:1902977//mitotic DNA replication preinitiation complex assembly	--
ENSG00000093010	109.598	106.42	113.649	106.914	119.148	112.585	2705	2649	2067	2067	2542	2051	COMT	catechol-O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:2228]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Nervous system;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04728//Dopaminergic synapse;ko00140//Steroid hormone biosynthesis;ko00350//Tyrosine metabolism	K00545;K00545;K00545;K00545	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0016206//catechol O-methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0102084//L-dopa O-methyltransferase activity;GO:0102938//orcinol O-methyltransferase activity	GO:0006584//catecholamine metabolic process;GO:0006629//lipid metabolic process;GO:0016036//cellular response to phosphate starvation;GO:0032259//methylation;GO:0032502//developmental process;GO:0042135//neurotransmitter catabolic process;GO:0042417//dopamine metabolic process;GO:0042420//dopamine catabolic process;GO:0042424//catecholamine catabolic process	--
ENSG00000093072	2.543	3.788	3.367	3.072	3.152	2.61	169	253	165	151	181	126	ADA2	adenosine deaminase 2 [Source:HGNC Symbol;Acc:HGNC:1839]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K19572;K19572	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen	GO:0004000//adenosine deaminase activity;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0019239//deaminase activity;GO:0031685//adenosine receptor binding;GO:0042803//protein homodimerization activity;GO:0043394//proteoglycan binding;GO:0046872//metal ion binding	GO:0006154//adenosine catabolic process;GO:0007165//signal transduction;GO:0046103//inosine biosynthetic process;GO:0072521//purine-containing compound metabolic process	--
ENSG00000093144	43.14	34.4	40.434	39.255	37.05	53.283	1593	1367	1121	1152	1169	1395	ECHDC1	ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00640//Propanoate metabolism	K18426;K18426	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity	GO:0006635//fatty acid beta-oxidation	--
ENSG00000093167	16.626	15.851	12.82	12.054	13.918	15.419	877	779	508	444	591	595	LRRFIP2	LRR binding FLII interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:6703]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0030275//LRR domain binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008150//biological_process;GO:0016055//Wnt signaling pathway"	LRRFIP
ENSG00000093183	13.143	16.301	13.592	13.512	14.126	16.309	1014	1078	759	811	879	819	SEC22C	"SEC22 homolog C, vesicle trafficking protein [Source:HGNC Symbol;Acc:HGNC:16828]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000093217	1.627	1.283	0.858	0.707	0.713	0.472	114	94	39	37	43	24	XYLB	xylulokinase [Source:HGNC Symbol;Acc:HGNC:12839]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00040//Pentose and glucuronate interconversions	K00854;K00854	GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0004856//xylulokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0005997//xylulose metabolic process;GO:0005998//xylulose catabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0016310//phosphorylation;GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0042732//D-xylose metabolic process;GO:0046835//carbohydrate phosphorylation	--
ENSG00000094631	24.47	25.365	26.394	25.049	27.682	26.26	1365	1378	1113	1107	1316	1160	HDAC6	histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Immune system;Cancer: overview;Substance dependence	ko05014//Amyotrophic lateral sclerosis;ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11407;K11407;K11407;K11407	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005771//multivesicular body;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005901//caveola;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016234//inclusion body;GO:0016235//aggresome;GO:0030424//axon;GO:0030425//dendrite;GO:0031252//cell leading edge;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:1904115//axon cytoplasm	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0003779//actin binding;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0033558//protein deacetylase activity;GO:0042826//histone deacetylase binding;GO:0042903//tubulin deacetylase activity;GO:0043014//alpha-tubulin binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0048487//beta-tubulin binding;GO:0051787//misfolded protein binding;GO:0051879//Hsp90 protein binding;GO:0070840//dynein complex binding	"GO:0000209//protein polyubiquitination;GO:0006325//chromatin organization;GO:0006476//protein deacetylation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0007026//negative regulation of microtubule depolymerization;GO:0010506//regulation of autophagy;GO:0010634//positive regulation of epithelial cell migration;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0016241//regulation of macroautophagy;GO:0016575//histone deacetylation;GO:0019896//axonal transport of mitochondrion;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0032418//lysosome localization;GO:0032984//protein-containing complex disassembly;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034983//peptidyl-lysine deacetylation;GO:0035967//cellular response to topologically incorrect protein;GO:0040029//regulation of gene expression, epigenetic;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0043242//negative regulation of protein-containing complex disassembly;GO:0045598//regulation of fat cell differentiation;GO:0045861//negative regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048668//collateral sprouting;GO:0051354//negative regulation of oxidoreductase activity;GO:0051646//mitochondrion localization;GO:0051788//response to misfolded protein;GO:0060271//cilium assembly;GO:0060632//regulation of microtubule-based movement;GO:0060765//regulation of androgen receptor signaling pathway;GO:0060997//dendritic spine morphogenesis;GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0070201//regulation of establishment of protein localization;GO:0070301//cellular response to hydrogen peroxide;GO:0070842//aggresome assembly;GO:0070845//polyubiquitinated misfolded protein transport;GO:0070846//Hsp90 deacetylation;GO:0070848//response to growth factor;GO:0071218//cellular response to misfolded protein;GO:0090042//tubulin deacetylation;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:1903146//regulation of autophagy of mitochondrion;GO:2000273//positive regulation of signaling receptor activity"	--
ENSG00000094661	0	0	0	0	0	0	0	0	0	0	0	0	OR1I1	olfactory receptor family 1 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:8207]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000094755	0.147	0.102	0	0.152	0	0.04	3	7	0	3	0	2	GABRP	gamma-aminobutyric acid type A receptor subunit pi [Source:HGNC Symbol;Acc:HGNC:4089]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05189;K05189;K05189;K05189;K05189	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:1902476//chloride transmembrane transport	--
ENSG00000094796	0	0	0	0	0	0	0	0	0	0	0	0	KRT31	keratin 31 [Source:HGNC Symbol;Acc:HGNC:6448]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000094804	1.384	1.495	1.799	0.649	1.714	0.89	76	89	57	31	64	34	CDC6	cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744]	Human Diseases;Cellular Processes	Cancer: overview;Cell growth and death	ko05207//Chemical carcinogenesis - receptor activation;ko04110//Cell cycle	K02213;K02213	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge;GO:0051233//spindle midzone;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003688//DNA replication origin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019900//kinase binding	GO:0000076//DNA replication checkpoint signaling;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:0007089//traversing start control point of mitotic cell cycle;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0032467//positive regulation of cytokinesis;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048146//positive regulation of fibroblast proliferation;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:1904117//cellular response to vasopressin;GO:1904385//cellular response to angiotensin	--
ENSG00000094841	7.76	9.036	7.349	6.787	6.722	6.796	358	367	228	236	262	212	UPRT	uracil phosphoribosyltransferase homolog [Source:HGNC Symbol;Acc:HGNC:28334]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006222//UMP biosynthetic process;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0032868//response to insulin	--
ENSG00000094880	14.276	13.162	11.989	13.35	16.029	14.385	791	803	525	582	720	645	CDC23	cell division cycle 23 [Source:HGNC Symbol;Acc:HGNC:1724]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03355;K03355;K03355;K03355;K03355	GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007096//regulation of exit from mitosis;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000094914	19.662	21.475	23.388	24.272	22.749	24.217	747	818	658	685	730	673	AAAS	aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14320	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0072686//mitotic spindle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001578//microtubule bundle formation;GO:0006913//nucleocytoplasmic transport;GO:0007612//learning;GO:0009566//fertilization;GO:0015031//protein transport;GO:0046822//regulation of nucleocytoplasmic transport;GO:0051028//mRNA transport;GO:0090307//mitotic spindle assembly	--
ENSG00000094916	67.659	65.813	67.706	52.571	55.39	59.209	9080	8440	6882	5786	6918	6107	CBX5	chromobox 5 [Source:HGNC Symbol;Acc:HGNC:1555]	-	-	-	-	"GO:0000118//histone deacetylase complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000781//chromosome, telomeric region;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005730//nucleolus;GO:0010369//chromocenter;GO:0016605//PML body;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex;GO:0035097//histone methyltransferase complex;GO:0090734//site of DNA damage;GO:1990904//ribonucleoprotein complex"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043021//ribonucleoprotein complex binding;GO:0044877//protein-containing complex binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000094963	0.508	0.432	0.739	0.761	0.613	0.972	55	47	59	61	56	63	FMO2	flavin containing dimethylaniline monoxygenase 2 [Source:HGNC Symbol;Acc:HGNC:3770]	Metabolism;Metabolism	Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko00982//Drug metabolism - cytochrome P450;ko00430//Taurine and hypotaurine metabolism	K00485;K00485	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	GO:0006082//organic acid metabolic process;GO:0006739//NADP metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009404//toxin metabolic process;GO:0070995//NADPH oxidation;GO:0072592//oxygen metabolic process	--
ENSG00000094975	11.463	8.284	8.039	6.22	6.779	8.782	1351	981	699	544	676	752	SUCO	SUN domain containing ossification factor [Source:HGNC Symbol;Acc:HGNC:1240]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030867//rough endoplasmic reticulum membrane	-	GO:0001503//ossification;GO:0032967//positive regulation of collagen biosynthetic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0046850//regulation of bone remodeling	--
ENSG00000095002	17.681	15.662	15.257	13.137	15.006	16.743	1145.51	1018	730.14	632.39	820	788	MSH2	mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Replication and repair	ko05200//Pathways in cancer;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko03430//Mismatch repair	K08735;K08735;K08735;K08735	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032300//mismatch repair complex;GO:0032301//MutSalpha complex;GO:0032302//MutSbeta complex"	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016887//ATP hydrolysis activity;GO:0019237//centromeric DNA binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030983//mismatched DNA binding;GO:0032137//guanine/thymine mispair binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0032142//single guanine insertion binding;GO:0032143//single thymine insertion binding;GO:0032181//dinucleotide repeat insertion binding;GO:0032357//oxidized purine DNA binding;GO:0032405//MutLalpha complex binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding"	GO:0001701//in utero embryonic development;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0006119//oxidative phosphorylation;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006301//postreplication repair;GO:0006302//double-strand break repair;GO:0006312//mitotic recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007281//germ cell development;GO:0008340//determination of adult lifespan;GO:0008584//male gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010165//response to X-ray;GO:0010224//response to UV-B;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0019724//B cell mediated immunity;GO:0030183//B cell differentiation;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043524//negative regulation of neuron apoptotic process;GO:0043570//maintenance of DNA repeat elements;GO:0045190//isotype switching;GO:0045910//negative regulation of DNA recombination;GO:0048298//positive regulation of isotype switching to IgA isotypes;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050896//response to stimulus;GO:0051096//positive regulation of helicase activity;GO:0051726//regulation of cell cycle;GO:0071168//protein localization to chromatin	--
ENSG00000095015	4.543	3.865	4.518	3.552	4.363	4.699	663	567	487	384	538	499	MAP3K1	mitogen-activated protein kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6848]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	"Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Folding, sorting and degradation;Nervous system;Endocrine system;Endocrine system;Immune system"	"ko04010//MAPK signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04530//Tight junction;ko05161//Hepatitis B;ko04120//Ubiquitin mediated proteolysis;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04912//GnRH signaling pathway;ko04622//RIG-I-like receptor signaling pathway"	K04416;K04416;K04416;K04416;K04416;K04416;K04416;K04416;K04416	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000095059	23.312	24.05	26.436	31.486	28.314	30.39	627.32	646.64	538.51	611.58	655.96	594.43	DHPS	deoxyhypusine synthase [Source:HGNC Symbol;Acc:HGNC:2869]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034038//deoxyhypusine synthase activity;GO:0042802//identical protein binding	GO:0006412//translation;GO:0008216//spermidine metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008612//peptidyl-lysine modification to peptidyl-hypusine	--
ENSG00000095066	3.294	2.666	2.865	3.086	4.914	3.705	139	138	100	120	169	136	HOOK2	hook microtubule tethering protein 2 [Source:HGNC Symbol;Acc:HGNC:19885]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030897//HOPS complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070695//FHF complex	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0051959//dynein light intermediate chain binding	GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization;GO:0045022//early endosome to late endosome transport;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000095110	0	0	0	0	0	0	0	0	0	0	0	0	NXPE1	neurexophilin and PC-esterase domain family member 1 [Source:HGNC Symbol;Acc:HGNC:28527]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000095139	41.559	41.66	38.604	34.072	36.605	38.381	3378	3364	2362	2079	2562	2300	ARCN1	archain 1 [Source:HGNC Symbol;Acc:HGNC:649]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0008344//adult locomotory behavior;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0021691//cerebellar Purkinje cell layer maturation;GO:0043473//pigmentation;GO:0048193//Golgi vesicle transport;GO:0051645//Golgi localization"	--
ENSG00000095203	36.322	35.542	40.058	40.832	38.432	48.618	3077	3007	2494	2555	2753	3005	EPB41L4B	erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21111	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0030054//cell junction;GO:0045177//apical part of cell	GO:0005200//structural constituent of cytoskeleton;GO:0008092//cytoskeletal protein binding	GO:0010628//positive regulation of gene expression;GO:0031032//actomyosin structure organization;GO:0042060//wound healing;GO:0045785//positive regulation of cell adhesion;GO:0051549//positive regulation of keratinocyte migration	--
ENSG00000095209	14.34	13.888	16.241	13.672	14.185	17.492	933	824	635	587	693	724	TMEM38B	transmembrane protein 38B [Source:HGNC Symbol;Acc:HGNC:25535]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane	GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001503//ossification;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007029//endoplasmic reticulum organization;GO:0008654//phospholipid biosynthetic process;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0030282//bone mineralization;GO:0048286//lung alveolus development;GO:0051209//release of sequestered calcium ion into cytosol;GO:0060348//bone development;GO:0060487//lung epithelial cell differentiation;GO:0061033//secretion by lung epithelial cell involved in lung growth;GO:0070278//extracellular matrix constituent secretion;GO:0071313//cellular response to caffeine;GO:0071805//potassium ion transmembrane transport;GO:1903514//release of sequestered calcium ion into cytosol by endoplasmic reticulum	--
ENSG00000095261	21.339	15.664	15.574	31.417	12.591	40.612	930	893	711	659	746	692	PSMD5	"proteasome 26S subunit, non-ATPase 5 [Source:HGNC Symbol;Acc:HGNC:9563]"	-	-	-	-	"GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0022624//proteasome accessory complex"	GO:0005515//protein binding	GO:0043248//proteasome assembly;GO:0070682//proteasome regulatory particle assembly	--
ENSG00000095303	0.385	0.923	0.971	0.57	0.881	1.315	30	47	54	44	54	60	PTGS1	prostaglandin-endoperoxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:9604]	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Immune system;Nervous system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04611//Platelet activation;ko04726//Serotonergic synapse;ko00590//Arachidonic acid metabolism;ko04923//Regulation of lipolysis in adipocytes	K00509;K00509;K00509;K00509;K00509	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004601//peroxidase activity;GO:0004666//prostaglandin-endoperoxide synthase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0008217//regulation of blood pressure;GO:0019371//cyclooxygenase pathway;GO:0042127//regulation of cell population proliferation;GO:0071704//organic substance metabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000095319	13.229	13.262	14.136	14.404	13.852	12.987	1561	1573	1231.97	1259	1380.93	1115	NUP188	nucleoporin 188 [Source:HGNC Symbol;Acc:HGNC:17859]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14311;K14311	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0016020//membrane;GO:0044611//nuclear pore inner ring	GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000095321	23.043	27.06	24.823	27.422	27.412	25.9	1201	1410	964	1056	1221	992	CRAT	carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K00624	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane	GO:0003997//acyl-CoA oxidase activity;GO:0004092//carnitine O-acetyltransferase activity;GO:0008458//carnitine O-octanoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0019254//carnitine metabolic process, CoA-linked;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0046459//short-chain fatty acid metabolic process;GO:0051791//medium-chain fatty acid metabolic process"	--
ENSG00000095370	0.136	0.183	0.39	0.142	0.257	0.582	7	7	6	6	12	10	SH2D3C	SH2 domain containing 3C [Source:HGNC Symbol;Acc:HGNC:16884]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007254//JNK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0050790//regulation of catalytic activity	--
ENSG00000095380	23.081	22.828	20.652	19.874	18.676	19.389	565	558	373	360	386	345	NANS	N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K05304;K05304	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0008781//N-acylneuraminate cytidylyltransferase activity;GO:0016740//transferase activity;GO:0047444//N-acylneuraminate-9-phosphate synthase activity;GO:0050462//N-acetylneuraminate synthase activity	GO:0006055//CMP-N-acetylneuraminate biosynthetic process;GO:0016051//carbohydrate biosynthetic process;GO:0070085//glycosylation	--
ENSG00000095383	11.794	13.488	11.171	13.528	13.77	11.737	780	904	550	670	778	568	TBC1D2	TBC1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:18026]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0043547//positive regulation of GTPase activity;GO:0090630//activation of GTPase activity	--
ENSG00000095397	13.845	14.72	13.169	13.454	14.603	14.262	838	833	558	586	774	603	WHRN	whirlin [Source:HGNC Symbol;Acc:HGNC:16361]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0002141//stereocilia ankle link;GO:0002142//stereocilia ankle link complex;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0030054//cell junction;GO:0030426//growth cone;GO:0032391//photoreceptor connecting cilium;GO:0032420//stereocilium;GO:0032421//stereocilium bundle;GO:0032426//stereocilium tip;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:1990075//periciliary membrane compartment;GO:1990696//USH2 complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001895//retina homeostasis;GO:0007605//sensory perception of sound;GO:0010628//positive regulation of gene expression;GO:0021694//cerebellar Purkinje cell layer formation;GO:0045184//establishment of protein localization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0060088//auditory receptor cell stereocilium organization;GO:0060122//inner ear receptor cell stereocilium organization;GO:1990227//paranodal junction maintenance	--
ENSG00000095464	0	0	0	0	0	0	0	0	0	0	0	0	PDE6C	phosphodiesterase 6C [Source:HGNC Symbol;Acc:HGNC:8787]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13757;K13757	GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030553//cGMP binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	"GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007603//phototransduction, visible light;GO:0046549//retinal cone cell development;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus"	--
ENSG00000095485	2.897	2.758	2.091	2.668	2.273	2.192	136	145	83	100	93	85	CWF19L1	CWF19 like cell cycle control factor 1 [Source:HGNC Symbol;Acc:HGNC:25613]	-	-	-	-	GO:0005575//cellular_component;GO:0071014//post-mRNA release spliceosomal complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0061632//RNA lariat debranching enzyme activator activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0008150//biological_process;GO:0050790//regulation of catalytic activity"	--
ENSG00000095539	12.749	15.715	16.588	13.167	14.383	14.681	731.87	759	608.88	606.59	624.22	571.81	SEMA4G	semaphorin 4G [Source:HGNC Symbol;Acc:HGNC:10735]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000095564	4.705	4.067	3.638	2.631	3.119	3.598	816	709	466	338	457	454	BTAF1	B-TFIID TATA-box binding protein associated factor 1 [Source:HGNC Symbol;Acc:HGNC:17307]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017025//TBP-class protein binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0006338//chromatin remodeling;GO:0035562//negative regulation of chromatin binding;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000095574	4.213	3.493	3.14	2.686	3.022	3.509	396	330	218	187	240	240	IKZF5	IKAROS family zinc finger 5 [Source:HGNC Symbol;Acc:HGNC:14283]	-	-	-	-	GO:0005634//nucleus;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000095585	1.389	1.186	0.714	0.65	1.394	0.684	42	42	19	17	38	16	BLNK	B cell linker [Source:HGNC Symbol;Acc:HGNC:14211]	Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Signal transduction;Immune system;Development and regeneration;Immune disease	ko05169//Epstein-Barr virus infection;ko04064//NF-kappa B signaling pathway;ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation;ko05340//Primary immunodeficiency	K07371;K07371;K07371;K07371;K07371	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding;GO:0043274//phospholipase binding;GO:1990782//protein tyrosine kinase binding	GO:0006954//inflammatory response;GO:0006959//humoral immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010628//positive regulation of gene expression;GO:0030183//B cell differentiation;GO:0035556//intracellular signal transduction;GO:0042113//B cell activation;GO:0050853//B cell receptor signaling pathway	--
ENSG00000095587	0.043	0.071	0	0.067	0.051	0.02	6	10	0	7	6	2	TLL2	tolloid like 2 [Source:HGNC Symbol;Acc:HGNC:11844]	-	-	-	-	GO:0005576//extracellular region	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0048632//negative regulation of skeletal muscle tissue growth	--
ENSG00000095596	0.601	0.925	0.493	0.545	0.274	0.501	25	40	16	13	7	11	CYP26A1	cytochrome P450 family 26 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2603]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K07437;K07437	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0001972//retinoic acid binding;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0062182//all-trans retinoic acid 4-hydrolase activity;GO:0062183//all-trans retinoic acid 18-hydroxylase activity"	GO:0001822//kidney development;GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0016125//sterol metabolic process;GO:0032526//response to retinoic acid;GO:0033189//response to vitamin A;GO:0034653//retinoic acid catabolic process;GO:0042573//retinoic acid metabolic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway	--
ENSG00000095627	0	0	0	0	0.012	0	0	0	0	0	1	0	TDRD1	tudor domain containing 1 [Source:HGNC Symbol;Acc:HGNC:11712]	-	-	-	-	GO:0005737//cytoplasm;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0071546//pi-body;GO:1990904//ribonucleoprotein complex	GO:0046872//metal ion binding	GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000095637	1.896	2.835	2.685	2.339	2.74	1.755	224	248	162	150	187	140	SORBS1	sorbin and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14565]	Organismal Systems;Organismal Systems;Cellular Processes	Endocrine system;Endocrine system;Cellular community - eukaryotes	ko04910//Insulin signaling pathway;ko03320//PPAR signaling pathway;ko04520//Adherens junction	K06086;K06086;K06086	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016600//flotillin complex;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0045121//membrane raft	GO:0003779//actin binding;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0030159//signaling receptor complex adaptor activity	GO:0007160//cell-matrix adhesion;GO:0008286//insulin receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0032869//cellular response to insulin stimulus;GO:0043149//stress fiber assembly;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048041//focal adhesion assembly;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000095713	21.943	23.824	24.756	16.61	16.365	22.257	1139	1216	941	649	711	771	CRTAC1	cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007413//axonal fasciculation	--
ENSG00000095739	26.002	22.663	25.632	28.79	32.329	35.148	912	799	664	748	958	897	BAMBI	BMP and activin membrane bound inhibitor [Source:HGNC Symbol;Acc:HGNC:30251]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04350//TGF-beta signaling pathway	K10162;K10162	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005109//frizzled binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005515//protein binding	"GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0032092//positive regulation of protein binding;GO:0045668//negative regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090263//positive regulation of canonical Wnt signaling pathway"	--
ENSG00000095752	0.08	0.049	0.201	0.071	0.266	0.247	2	2	2	2	8	4	IL11	interleukin 11 [Source:HGNC Symbol;Acc:HGNC:5966]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Immune system;Signal transduction;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko05323//Rheumatoid arthritis	K05417;K05417;K05417;K05417	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0005142//interleukin-11 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0030183//B cell differentiation;GO:0030219//megakaryocyte differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046888//negative regulation of hormone secretion;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation	--
ENSG00000095777	0.094	0.101	0.154	0.29	0.134	0.035	9	9	9	13	8	3	MYO3A	myosin IIIA [Source:HGNC Symbol;Acc:HGNC:7601]	Organismal Systems	Sensory system	ko04745//Phototransduction - fly	K08834	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016459//myosin complex;GO:0030175//filopodium;GO:0031941//filamentous actin;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0032433//filopodium tip;GO:0042995//cell projection	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043531//ADP binding;GO:0060002//plus-end directed microfilament motor activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0016310//phosphorylation;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus;GO:0090103//cochlea morphogenesis	--
ENSG00000095787	48.556	47.673	37.105	33.77	36.837	44.309	2675	2346	1452	1288	1572	1602	WAC	WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;Acc:HGNC:17327]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck	GO:0000993//RNA polymerase II complex binding;GO:0003682//chromatin binding;GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0010390//histone monoubiquitination;GO:0010506//regulation of autophagy;GO:0016239//positive regulation of macroautophagy;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071894//histone H2B conserved C-terminal lysine ubiquitination;GO:1904263//positive regulation of TORC1 signaling"	--
ENSG00000095794	15.526	15.795	15.072	14.099	13.557	13.137	381	381	263	243	269	245	CREM	cAMP responsive element modulator [Source:HGNC Symbol;Acc:HGNC:2352]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K09052	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:1990589//ATF4-CREB1 transcription factor complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006687//glycosphingolipid metabolic process;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	TF_bZIP
ENSG00000095906	23.361	25.022	26.224	33.282	28.389	28.103	627	675	514	659	649	558	NUBP2	nucleotide binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8042]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031616//spindle pole centrosome;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0030030//cell projection organization	--
ENSG00000095917	0	0	0	0	0	0	0	0	0	0	0	0	TPSD1	tryptase delta 1 [Source:HGNC Symbol;Acc:HGNC:14118]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K01340	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000095932	0.808	0.866	0.941	0.776	0.809	0.785	22	15	10	14	12	9	SMIM24	small integral membrane protein 24 [Source:HGNC Symbol;Acc:HGNC:37244]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000095951	5.762	5.966	4.478	3.116	4.836	4.519	852	614	457	310	496	431	HIVEP1	HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030509//BMP signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000095970	0	0	0	0	0.058	0.067	0	0	0	0	1	1	TREM2	triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K14378	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0044853//plasma membrane raft	GO:0001530//lipopolysaccharide binding;GO:0001540//amyloid-beta binding;GO:0001786//phosphatidylserine binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0019209//kinase activator activity;GO:0030169//low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0034186//apolipoprotein A-I binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0038023//signaling receptor activity;GO:0042834//peptidoglycan binding;GO:0044877//protein-containing complex binding;GO:0070891//lipoteichoic acid binding;GO:0071813//lipoprotein particle binding;GO:0097110//scaffold protein binding;GO:0120146//sulfatide binding;GO:1990782//protein tyrosine kinase binding	"GO:0001774//microglial cell activation;GO:0001934//positive regulation of protein phosphorylation;GO:0002282//microglial cell activation involved in immune response;GO:0002588//positive regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0002931//response to ischemia;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006959//humoral immune response;GO:0007613//memory;GO:0010468//regulation of gene expression;GO:0010507//negative regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010822//positive regulation of mitochondrion organization;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0010891//negative regulation of sequestering of triglyceride;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019216//regulation of lipid metabolic process;GO:0030316//osteoclast differentiation;GO:0032006//regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0032497//detection of lipopolysaccharide;GO:0032499//detection of peptidoglycan;GO:0032675//regulation of interleukin-6 production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0033674//positive regulation of kinase activity;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0034151//regulation of toll-like receptor 6 signaling pathway;GO:0034241//positive regulation of macrophage fusion;GO:0034351//negative regulation of glial cell apoptotic process;GO:0035176//social behavior;GO:0038160//CXCL12-activated CXCR4 signaling pathway;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043277//apoptotic cell clearance;GO:0045088//regulation of innate immune response;GO:0045672//positive regulation of osteoclast differentiation;GO:0045728//respiratory burst after phagocytosis;GO:0045960//positive regulation of complement activation, classical pathway;GO:0048143//astrocyte activation;GO:0048678//response to axon injury;GO:0050714//positive regulation of protein secretion;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766//positive regulation of phagocytosis;GO:0050829//defense response to Gram-negative bacterium;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050866//negative regulation of cell activation;GO:0050921//positive regulation of chemotaxis;GO:0055088//lipid homeostasis;GO:0060075//regulation of resting membrane potential;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0061518//microglial cell proliferation;GO:0061889//negative regulation of astrocyte activation;GO:0070269//pyroptosis;GO:0070345//negative regulation of fat cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070392//detection of lipoteichoic acid;GO:0071223//cellular response to lipoteichoic acid;GO:0071224//cellular response to peptidoglycan;GO:0071333//cellular response to glucose stimulus;GO:0071396//cellular response to lipid;GO:0071456//cellular response to hypoxia;GO:0071640//regulation of macrophage inflammatory protein 1 alpha production;GO:0097028//dendritic cell differentiation;GO:0097062//dendritic spine maintenance;GO:0097242//amyloid-beta clearance;GO:0098657//import into cell;GO:0110089//regulation of hippocampal neuron apoptotic process;GO:0120035//regulation of plasma membrane bounded cell projection organization;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0150062//complement-mediated synapse pruning;GO:0150076//neuroinflammatory response;GO:0150078//positive regulation of neuroinflammatory response;GO:0150079//negative regulation of neuroinflammatory response;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900223//positive regulation of amyloid-beta clearance;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1901076//positive regulation of engulfment of apoptotic cell;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1901980//positive regulation of inward rectifier potassium channel activity;GO:1902227//negative regulation of macrophage colony-stimulating factor signaling pathway;GO:1902531//regulation of intracellular signal transduction;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903082//positive regulation of C-C chemokine receptor CCR7 signaling pathway;GO:1903376//regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903753//negative regulation of p38MAPK cascade;GO:1903980//positive regulation of microglial cell activation;GO:1904093//negative regulation of autophagic cell death;GO:1904141//positive regulation of microglial cell migration;GO:1904646//cellular response to amyloid-beta;GO:1904951//positive regulation of establishment of protein localization;GO:1905291//positive regulation of CAMKK-AMPK signaling cascade;GO:1905581//positive regulation of low-density lipoprotein particle clearance;GO:1905805//excitatory synapse pruning;GO:1905808//positive regulation of synapse pruning;GO:1905907//negative regulation of amyloid fibril formation;GO:2000350//positive regulation of CD40 signaling pathway;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000095981	0	0	0	0	0	0	0	0	0	0	0	0	KCNK16	potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000096006	0.022	0	0	0	0.117	0	1	0	0	0	2	0	CRISP3	cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:0042581//specific granule;GO:1904724//tertiary granule lumen	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006952//defense response;GO:0045087//innate immune response	--
ENSG00000096060	1.401	1.305	1.253	1.128	0.7	1.096	110	103	72	65	46	62	FKBP5	FKBP prolyl isomerase 5 [Source:HGNC Symbol;Acc:HGNC:3721]	Organismal Systems	Endocrine system	ko04915//Estrogen signaling pathway	K09571	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0031072//heat shock protein binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0009617//response to bacterium;GO:0061077//chaperone-mediated protein folding	--
ENSG00000096063	11.68	12.773	11.037	9.579	9.291	10.61	972.31	1037.11	735.44	627.01	693.61	682.77	SRPK1	SRSF protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:11305]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K15409	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000245//spliceosomal complex assembly;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0007059//chromosome segregation;GO:0008380//RNA splicing;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035092//sperm chromatin condensation;GO:0035556//intracellular signal transduction;GO:0045070//positive regulation of viral genome replication;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0050684//regulation of mRNA processing"	--
ENSG00000096070	9.27	8.668	7.957	8.131	8.019	10.958	1083	1023	700	687	823	919	BRPF3	bromodomain and PHD finger containing 3 [Source:HGNC Symbol;Acc:HGNC:14256]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045740//positive regulation of DNA replication;GO:0050793//regulation of developmental process;GO:1903706//regulation of hemopoiesis"	--
ENSG00000096080	33.002	37.415	39.644	41.383	40.716	37.385	759.23	875.66	669.44	712.35	790.36	622.25	MRPS18A	mitochondrial ribosomal protein S18A [Source:HGNC Symbol;Acc:HGNC:14515]	Genetic Information Processing	Translation	ko03010//Ribosome	K02963	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0070181//small ribosomal subunit rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000096088	0	0	0	0	0	0	0	0	0	0	0	0	PGC	progastricsin [Source:HGNC Symbol;Acc:HGNC:8890]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0002803//positive regulation of antibacterial peptide production;GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000096092	31.62	27.963	34.489	32.016	24.258	35.142	648	576	522	486	420	524	TMEM14A	transmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0070453//regulation of heme biosynthetic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	--
ENSG00000096093	16.314	14.978	16.435	14.28	15.008	14.385	915	842	652	593	706	618	EFHC1	EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16406]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0043025//neuronal cell body;GO:0072686//mitotic spindle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043014//alpha-tubulin binding	GO:0000281//mitotic cytokinesis;GO:0007052//mitotic spindle organization;GO:0021795//cerebral cortex cell migration;GO:0051302//regulation of cell division;GO:0060285//cilium-dependent cell motility	--
ENSG00000096264	0	0	0	0	0	0	0	0	0	0	0	0	NCR2	natural cytotoxicity triggering receptor 2 [Source:HGNC Symbol;Acc:HGNC:6732]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K06742	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006968//cellular defense response;GO:0007165//signal transduction	--
ENSG00000096384	472.248	468.199	441.016	459.445	461.282	389.862	25030	24942	17263	18037	20657	15034	HSP90AB1	heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Genetic Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	"Cancer: overview;Signal transduction;Infectious disease: bacterial;Cardiovascular disease;Cancer: overview;Immune system;Folding, sorting and degradation;Cell growth and death;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Cancer: specific types;Immune system;Immune system"	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko04621//NOD-like receptor signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04217//Necroptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04659//Th17 cell differentiation;ko05215//Prostate cancer;ko04657//IL-17 signaling pathway;ko04612//Antigen processing and presentation	K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079;K04079	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0009986//cell surface;GO:0016020//membrane;GO:0016234//inclusion body;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0032991//protein-containing complex;GO:0034751//aryl hydrocarbon receptor complex;GO:0034774//secretory granule lumen;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0120293//dynein axonemal particle;GO:1904813//ficolin-1-rich granule lumen;GO:1990565//HSP90-CDC37 chaperone complex;GO:1990913//sperm head plasma membrane;GO:1990917//ooplasm	GO:0000166//nucleotide binding;GO:0002134//UTP binding;GO:0002135//CTP binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016887//ATP hydrolysis activity;GO:0017098//sulfonylurea receptor binding;GO:0019887//protein kinase regulator activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0023026//MHC class II protein complex binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0030911//TPR domain binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0032564//dATP binding;GO:0042277//peptide binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043008//ATP-dependent protein binding;GO:0044183//protein folding chaperone;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0046983//protein dimerization activity;GO:0048156//tau protein binding;GO:0051082//unfolded protein binding;GO:0070182//DNA polymerase binding;GO:0097718//disordered domain specific binding;GO:1901363//heterocyclic compound binding;GO:1990226//histone methyltransferase binding	GO:0001890//placenta development;GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0007004//telomere maintenance via telomerase;GO:0009410//response to xenobiotic stimulus;GO:0009651//response to salt stress;GO:0010033//response to organic substance;GO:0019062//virion attachment to host cell;GO:0021955//central nervous system neuron axonogenesis;GO:0030010//establishment of cell polarity;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031396//regulation of protein ubiquitination;GO:0032092//positive regulation of protein binding;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034605//cellular response to heat;GO:0042220//response to cocaine;GO:0042307//positive regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045597//positive regulation of cell differentiation;GO:0045793//positive regulation of cell size;GO:0048675//axon extension;GO:0050821//protein stabilization;GO:0051131//chaperone-mediated protein complex assembly;GO:0051248//negative regulation of protein metabolic process;GO:0051726//regulation of cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0051973//positive regulation of telomerase activity;GO:0071353//cellular response to interleukin-4;GO:0071407//cellular response to organic cyclic compound;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097435//supramolecular fiber organization;GO:1901389//negative regulation of transforming growth factor beta activation;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:1902949//positive regulation of tau-protein kinase activity;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:1905323//telomerase holoenzyme complex assembly;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000096395	0	0	0	0	0	0	0	0	0	0	0	0	MLN	motilin [Source:HGNC Symbol;Acc:HGNC:7141]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05265	GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031788//motilin receptor binding	GO:0007165//signal transduction	--
ENSG00000096401	7.431	6.755	6.108	4.891	5.157	5.478	962	879	584	469	564	516	CDC5L	cell division cycle 5 like [Source:HGNC Symbol;Acc:HGNC:1743]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12860	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0071987//WD40-repeat domain binding"	"GO:0000077//DNA damage checkpoint signaling;GO:0000398//mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0045944//positive regulation of transcription by RNA polymerase II"	MYB
ENSG00000096433	0.77	0.967	0.856	1.162	1.263	1.46	147	183	120	163	201	200	ITPR3	"inositol 1,4,5-trisphosphate receptor type 3 [Source:HGNC Symbol;Acc:HGNC:6182]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Nervous system;Neurodegenerative disease;Cell growth and death;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine system;Nervous system;Nervous system;Nervous system;Immune system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Sensory system;Digestive system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04114//Oocyte meiosis;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression"	K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960;K04960	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031095//platelet dense tubular network membrane;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0043235//receptor complex;GO:0045177//apical part of cell	"GO:0000822//inositol hexakisphosphate binding;GO:0005216//ion channel activity;GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015278//calcium-release channel activity;GO:0035091//phosphatidylinositol binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007613//memory;GO:0048016//inositol phosphate-mediated signaling;GO:0050909//sensory perception of taste;GO:0050913//sensory perception of bitter taste;GO:0050916//sensory perception of sweet taste;GO:0050917//sensory perception of umami taste;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0060402//calcium ion transport into cytosol;GO:0070588//calcium ion transmembrane transport	--
ENSG00000096654	4.481	3.49	3.717	2.919	2.553	2.009	291	227	184	144	142	96	ZNF184	zinc finger protein 184 [Source:HGNC Symbol;Acc:HGNC:12975]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000096696	78.693	71.565	59.071	41.541	49.898	39.735	15026	13791	8231	5822	7978	5367	DSP	desmoplakin [Source:HGNC Symbol;Acc:HGNC:3052]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K10381	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005916//fascia adherens;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication;GO:0097110//scaffold protein binding	GO:0002934//desmosome organization;GO:0003223//ventricular compact myocardium morphogenesis;GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0034332//adherens junction organization;GO:0042060//wound healing;GO:0043588//skin development;GO:0045104//intermediate filament cytoskeleton organization;GO:0045109//intermediate filament organization;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090136//epithelial cell-cell adhesion;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:0150105//protein localization to cell-cell junction	--
ENSG00000096717	6.631	6.189	5.919	5.026	5.532	5.597	549	514	339	317	397	340	SIRT1	sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cancer: overview;Cell growth and death;Endocrine and metabolic disease;Signal transduction;Signal transduction;Endocrine system;Aging;Substance dependence;Aging;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05031//Amphetamine addiction;ko04213//Longevity regulating pathway - multiple species;ko00760//Nicotinate and nicotinamide metabolism	K11411;K11411;K11411;K11411;K11411;K11411;K11411;K11411;K11411;K11411;K11411	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016605//PML body;GO:0032991//protein-containing complex;GO:0033553//rDNA heterochromatin;GO:0035098//ESC/E(Z) complex;GO:0061773//eNoSc complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0002039//p53 binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016740//transferase activity;GO:0016922//nuclear receptor binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019213//deacetylase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0033558//protein deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0043398//HLH domain binding;GO:0043425//bHLH transcription factor binding;GO:0046872//metal ion binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0051019//mitogen-activated protein kinase binding;GO:0070403//NAD+ binding;GO:0106231//protein-propionyllysine depropionylase activity;GO:0140297//DNA-binding transcription factor binding;GO:1990254//keratin filament binding;GO:1990841//promoter-specific chromatin binding	"GO:0000012//single strand break repair;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000183//rDNA heterochromatin assembly;GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0000731//DNA synthesis involved in DNA repair;GO:0001525//angiogenesis;GO:0001542//ovulation from ovarian follicle;GO:0001678//cellular glucose homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002821//positive regulation of adaptive immune response;GO:0006325//chromatin organization;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0006476//protein deacetylation;GO:0006642//triglyceride mobilization;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007346//regulation of mitotic cell cycle;GO:0007517//muscle organ development;GO:0007569//cell aging;GO:0007623//circadian rhythm;GO:0008284//positive regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009267//cellular response to starvation;GO:0010629//negative regulation of gene expression;GO:0010824//regulation of centrosome duplication;GO:0010875//positive regulation of cholesterol efflux;GO:0010883//regulation of lipid storage;GO:0010906//regulation of glucose metabolic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016239//positive regulation of macroautophagy;GO:0016567//protein ubiquitination;GO:0016575//histone deacetylation;GO:0018394//peptidyl-lysine acetylation;GO:0030154//cell differentiation;GO:0030225//macrophage differentiation;GO:0030308//negative regulation of cell growth;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031062//positive regulation of histone methylation;GO:0031065//positive regulation of histone deacetylation;GO:0031393//negative regulation of prostaglandin biosynthetic process;GO:0031507//heterochromatin assembly;GO:0031648//protein destabilization;GO:0032007//negative regulation of TOR signaling;GO:0032071//regulation of endodeoxyribonuclease activity;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0033210//leptin-mediated signaling pathway;GO:0034391//regulation of smooth muscle cell apoptotic process;GO:0034983//peptidyl-lysine deacetylation;GO:0035356//cellular triglyceride homeostasis;GO:0035358//regulation of peroxisome proliferator activated receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042149//cellular response to glucose starvation;GO:0042326//negative regulation of phosphorylation;GO:0042542//response to hydrogen peroxide;GO:0042595//behavioral response to starvation;GO:0042632//cholesterol homeostasis;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0044321//response to leptin;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045599//negative regulation of fat cell differentiation;GO:0045722//positive regulation of gluconeogenesis;GO:0045739//positive regulation of DNA repair;GO:0045766//positive regulation of angiogenesis;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046015//regulation of transcription by glucose;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0048511//rhythmic process;GO:0050872//white fat cell differentiation;GO:0051097//negative regulation of helicase activity;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0051898//negative regulation of protein kinase B signaling;GO:0055089//fatty acid homeostasis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060907//positive regulation of macrophage cytokine production;GO:0061647//histone H3-K9 modification;GO:0070301//cellular response to hydrogen peroxide;GO:0070857//regulation of bile acid biosynthetic process;GO:0070914//UV-damage excision repair;GO:0070932//histone H3 deacetylation;GO:0071356//cellular response to tumor necrosis factor;GO:0071441//negative regulation of histone H3-K14 acetylation;GO:0071456//cellular response to hypoxia;GO:0071479//cellular response to ionizing radiation;GO:0071900//regulation of protein serine/threonine kinase activity;GO:0090335//regulation of brown fat cell differentiation;GO:0090400//stress-induced premature senescence;GO:0097009//energy homeostasis;GO:0106230//protein depropionylation;GO:1900034//regulation of cellular response to heat;GO:1900113//negative regulation of histone H3-K9 trimethylation;GO:1901215//negative regulation of neuron death;GO:1901984//negative regulation of protein acetylation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1904179//positive regulation of adipose tissue development;GO:1990619//histone H3-K9 deacetylation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000111//positive regulation of macrophage apoptotic process;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:2000619//negative regulation of histone H4-K16 acetylation;GO:2000655//negative regulation of cellular response to testosterone stimulus;GO:2000757//negative regulation of peptidyl-lysine acetylation;GO:2000773//negative regulation of cellular senescence;GO:2000774//positive regulation of cellular senescence"	--
ENSG00000096746	45.39	42.833	44.958	36.151	37.028	47.818	1947	1765	1380	1082	1313	1463	HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 [Source:HGNC Symbol;Acc:HGNC:5043]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0030855//epithelial cell differentiation;GO:0043484//regulation of RNA splicing"	--
ENSG00000096872	4.48	4.717	3.14	3.304	6.056	4.612	213	202	106	104	166	137	IFT74	intraflagellar transport 74 [Source:HGNC Symbol;Acc:HGNC:21424]	-	-	-	-	GO:0005634//nucleus;GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding	GO:0003334//keratinocyte development;GO:0007219//Notch signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008544//epidermis development;GO:0030030//cell projection organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035720//intraciliary anterograde transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0042073//intraciliary transport;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060271//cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000096968	1.098	1.298	1.254	0.778	1.379	1.101	160	146	100	84	120	115	JAK2	Janus kinase 2 [Source:HGNC Symbol;Acc:HGNC:6192]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: bacterial;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: parasitic;Cellular community - eukaryotes;Endocrine system;Nervous system;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Immune system;Cancer: overview;Drug resistance: antineoplastic;Endocrine system;Endocrine system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04917//Prolactin signaling pathway;ko04920//Adipocytokine signaling pathway"	K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447;K04447	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030526//granulocyte macrophage colony-stimulating factor receptor complex;GO:0031904//endosome lumen;GO:0042022//interleukin-12 receptor complex;GO:0045121//membrane raft;GO:0072536//interleukin-23 receptor complex;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005131//growth hormone receptor binding;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0020037//heme binding;GO:0031702//type 1 angiotensin receptor binding;GO:0033130//acetylcholine receptor binding;GO:0035401//histone kinase activity (H3-Y41 specific);GO:0042169//SH2 domain binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043560//insulin receptor substrate binding;GO:0046872//metal ion binding;GO:0051428//peptide hormone receptor binding	GO:0001774//microglial cell activation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006955//immune response;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0007498//mesoderm development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0009755//hormone-mediated signaling pathway;GO:0010572//positive regulation of platelet activation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010811//positive regulation of cell-substrate adhesion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014070//response to organic cyclic compound;GO:0014075//response to amine;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0030041//actin filament polymerization;GO:0030099//myeloid cell differentiation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030335//positive regulation of cell migration;GO:0031103//axon regeneration;GO:0031959//mineralocorticoid receptor signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:0032496//response to lipopolysaccharide;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032740//positive regulation of interleukin-17 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0033194//response to hydroperoxide;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034050//programmed cell death induced by symbiont;GO:0034612//response to tumor necrosis factor;GO:0035166//post-embryonic hemopoiesis;GO:0035409//histone H3-Y41 phosphorylation;GO:0035556//intracellular signal transduction;GO:0035722//interleukin-12-mediated signaling pathway;GO:0036016//cellular response to interleukin-3;GO:0038065//collagen-activated signaling pathway;GO:0038157//granulocyte-macrophage colony-stimulating factor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042307//positive regulation of protein import into nucleus;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042976//activation of Janus kinase activity;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0043392//negative regulation of DNA binding;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0045087//innate immune response;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045597//positive regulation of cell differentiation;GO:0045822//negative regulation of heart contraction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046677//response to antibiotic;GO:0046777//protein autophosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050804//modulation of chemical synaptic transmission;GO:0050867//positive regulation of cell activation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051142//positive regulation of NK T cell proliferation;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060396//growth hormone receptor signaling pathway;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0060399//positive regulation of growth hormone receptor signaling pathway;GO:0060548//negative regulation of cell death;GO:0061180//mammary gland epithelium development;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070665//positive regulation of leukocyte proliferation;GO:0070671//response to interleukin-12;GO:0070757//interleukin-35-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071549//cellular response to dexamethasone stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:0099527//postsynapse to nucleus signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901731//positive regulation of platelet aggregation;GO:1902728//positive regulation of growth factor dependent skeletal muscle satellite cell proliferation;GO:1904037//positive regulation of epithelial cell apoptotic process;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000273//positive regulation of signaling receptor activity;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000096996	0	0	0	0	0	0	0	0	0	0	0	0	IL12RB1	interleukin 12 receptor subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:5971]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K05063;K05063;K05063;K05063;K05063;K05063	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042022//interleukin-12 receptor complex;GO:0043235//receptor complex;GO:0072536//interleukin-23 receptor complex	GO:0004896//cytokine receptor activity;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0016517//interleukin-12 receptor activity;GO:0019955//cytokine binding;GO:0042019//interleukin-23 binding;GO:0042020//interleukin-23 receptor activity	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002230//positive regulation of defense response to virus by host;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0035722//interleukin-12-mediated signaling pathway;GO:0038155//interleukin-23-mediated signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0043382//positive regulation of memory T cell differentiation;GO:0071346//cellular response to interferon-gamma;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000330//positive regulation of T-helper 17 cell lineage commitment	--
ENSG00000097007	41.156	41.885	44.247	46.353	48.661	44.898	4506	4672	3459	3524	4524	3654	ABL1	"ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Infectious disease: bacterial;Signal transduction;Cancer: overview;Development and regeneration;Cancer: overview;Cardiovascular disease;Cell growth and death;Nervous system;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko05416//Viral myocarditis;ko04110//Cell cycle;ko04722//Neurotrophin signaling pathway;ko04012//ErbB signaling pathway;ko05220//Chronic myeloid leukemia	K06619;K06619;K06619;K06619;K06619;K06619;K06619;K06619;K06619;K06619;K06619	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000400//four-way junction DNA binding;GO:0000405//bubble DNA binding;GO:0001784//phosphotyrosine residue binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003785//actin monomer binding;GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0019905//syntaxin binding;GO:0030145//manganese ion binding;GO:0038191//neuropilin binding;GO:0042169//SH2 domain binding;GO:0046872//metal ion binding;GO:0046875//ephrin receptor binding;GO:0051015//actin filament binding;GO:0051019//mitogen-activated protein kinase binding;GO:0070064//proline-rich region binding;GO:0070097//delta-catenin binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0000278//mitotic cell cycle;GO:0001843//neural tube closure;GO:0001922//B-1 B cell homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0002322//B cell proliferation involved in immune response;GO:0002333//transitional one stage B cell differentiation;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0006909//phagocytosis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0006979//response to oxidative stress;GO:0007154//cell communication;GO:0007155//cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007229//integrin-mediated signaling pathway;GO:0007611//learning or memory;GO:0008306//associative learning;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009410//response to xenobiotic stimulus;GO:0009791//post-embryonic development;GO:0010506//regulation of autophagy;GO:0010595//positive regulation of endothelial cell migration;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021587//cerebellum morphogenesis;GO:0022408//negative regulation of cell-cell adhesion;GO:0023052//signaling;GO:0030035//microspike assembly;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030100//regulation of endocytosis;GO:0030155//regulation of cell adhesion;GO:0030182//neuron differentiation;GO:0030514//negative regulation of BMP signaling pathway;GO:0030516//regulation of axon extension;GO:0031113//regulation of microtubule polymerization;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0032956//regulation of actin cytoskeleton organization;GO:0033690//positive regulation of osteoblast proliferation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034599//cellular response to oxidative stress;GO:0034976//response to endoplasmic reticulum stress;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0038189//neuropilin signaling pathway;GO:0042100//B cell proliferation;GO:0042127//regulation of cell population proliferation;GO:0042770//signal transduction in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043525//positive regulation of neuron apoptotic process;GO:0043542//endothelial cell migration;GO:0045184//establishment of protein localization;GO:0045580//regulation of T cell differentiation;GO:0045907//positive regulation of vasoconstriction;GO:0045930//negative regulation of mitotic cell cycle;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046632//alpha-beta T cell differentiation;GO:0046777//protein autophosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048668//collateral sprouting;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050798//activated T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051353//positive regulation of oxidoreductase activity;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0051882//mitochondrial depolarization;GO:0051894//positive regulation of focal adhesion assembly;GO:0060020//Bergmann glial cell differentiation;GO:0060563//neuroepithelial cell differentiation;GO:0070301//cellular response to hydrogen peroxide;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071103//DNA conformation change;GO:0071222//cellular response to lipopolysaccharide;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071871//response to epinephrine;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0072359//circulatory system development;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090135//actin filament branching;GO:1900006//positive regulation of dendrite development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1900275//negative regulation of phospholipase C activity;GO:1901216//positive regulation of neuron death;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1903053//regulation of extracellular matrix organization;GO:1903055//positive regulation of extracellular matrix organization;GO:1903210//glomerular visceral epithelial cell apoptotic process;GO:1903351//cellular response to dopamine;GO:1904528//positive regulation of microtubule binding;GO:1904531//positive regulation of actin filament binding;GO:1905244//regulation of modification of synaptic structure;GO:1905555//positive regulation of blood vessel branching;GO:1990051//activation of protein kinase C activity;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:2000145//regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000772//regulation of cellular senescence;GO:2000773//negative regulation of cellular senescence;GO:2001020//regulation of response to DNA damage stimulus"	--
ENSG00000097021	5.82	8.271	8.541	8.42	7.158	6.643	174	251	174	197	200	150	ACOT7	acyl-CoA thioesterase 7 [Source:HGNC Symbol;Acc:HGNC:24157]	Metabolism;Metabolism	Lipid metabolism;Lipid metabolism	ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K17360;K17360	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0036042//long-chain fatty acyl-CoA binding;GO:0042803//protein homodimerization activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0036114//medium-chain fatty-acyl-CoA catabolic process;GO:0036116//long-chain fatty-acyl-CoA catabolic process;GO:0051792//medium-chain fatty acid biosynthetic process;GO:1900535//palmitic acid biosynthetic process	--
ENSG00000097033	17.779	15.222	15.631	13.719	13.842	16.392	2003	1458	1119	930	1082	1113	SH3GLB1	"SH3 domain containing GRB2 like, endophilin B1 [Source:HGNC Symbol;Acc:HGNC:10833]"	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04144//Endocytosis;ko04140//Autophagy - animal	K11248;K11248	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0010508//positive regulation of autophagy;GO:0016241//regulation of macroautophagy;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031647//regulation of protein stability;GO:0032465//regulation of cytokinesis;GO:0032801//receptor catabolic process;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0048102//autophagic cell death;GO:0061024//membrane organization;GO:0090148//membrane fission;GO:1903527//positive regulation of membrane tubulation;GO:1903778//protein localization to vacuolar membrane;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000097046	2.894	3.001	2.355	1.316	2.148	1.915	193	176	116	65	121	94	CDC7	cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02214	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000727//double-strand break repair via break-induced replication;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0044770//cell cycle phase transition;GO:0051301//cell division	--
ENSG00000097096	2.063	1.463	1.57	1.242	1.466	1.266	249	177	140	110	147	112	SYDE2	synapse defective Rho GTPase homolog 2 [Source:HGNC Symbol;Acc:HGNC:25841]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0016477//cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000099139	1.023	1.053	0.987	1.024	1.389	1.344	126	115	84	87	142	103	PCSK5	proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005802//trans-Golgi network;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042277//peptide binding	GO:0001822//kidney development;GO:0002001//renin secretion into blood stream;GO:0003279//cardiac septum development;GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0007267//cell-cell signaling;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007566//embryo implantation;GO:0009952//anterior/posterior pattern specification;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0019058//viral life cycle;GO:0030323//respiratory tube development;GO:0035108//limb morphogenesis;GO:0043043//peptide biosynthetic process;GO:0048566//embryonic digestive tract development;GO:0048706//embryonic skeletal system development;GO:0051004//regulation of lipoprotein lipase activity;GO:0060976//coronary vasculature development;GO:0140447//cytokine precursor processing	--
ENSG00000099194	177.532	173.149	177.051	199.242	199.819	228.899	19314	18934	14226	16056	18366	18119	SCD	stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Signal transduction;Endocrine system;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids	K00507;K00507;K00507;K00507;K00507;K00507	GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;GO:0032896//palmitoyl-CoA 9-desaturase activity;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0070542//response to fatty acid;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1903966//monounsaturated fatty acid biosynthetic process	--
ENSG00000099203	22.255	22.389	23.535	25.868	20.821	25.942	695	647.97	538	579.8	543.99	550	TMED1	transmembrane p24 trafficking protein 1 [Source:HGNC Symbol;Acc:HGNC:17291]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport	--
ENSG00000099204	42.832	41.28	33.073	33.512	45.055	33.82	4635	4574	2571	2811	3617	2642	ABLIM1	actin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:78]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07520	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0007601//visual perception;GO:0009887//animal organ morphogenesis;GO:0030032//lamellipodium assembly;GO:0060271//cilium assembly	--
ENSG00000099219	24.53	23.848	26.141	28.208	28.594	30.823	2680	2619	2128	2288	2679	2460	ERMP1	endoplasmic reticulum metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:23703]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034599//cellular response to oxidative stress	--
ENSG00000099246	60.046	52.041	51.193	55.407	47.668	57.211	2497	2180	1567	1545	1672	1720	RAB18	"RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14244]"	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030667//secretory granule membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0001654//eye development;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0007420//brain development;GO:0015031//protein transport;GO:0034389//lipid droplet organization;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000099250	2.046	2.474	1.223	2.577	2.662	2.295	151	158	69	145	168	113	NRP1	neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Development and regeneration	ko05171//Coronavirus disease - COVID-19;ko05166//Human T-cell leukemia virus 1 infection;ko04360//Axon guidance	K06724;K06724;K06724	GO:0002116//semaphorin receptor complex;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0097443//sorting endosome;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0015026//coreceptor activity;GO:0017154//semaphorin receptor activity;GO:0019838//growth factor binding;GO:0019901//protein kinase binding;GO:0019955//cytokine binding;GO:0038085//vascular endothelial growth factor binding;GO:0046872//metal ion binding	"GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001764//neuron migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007507//heart development;GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0010595//positive regulation of endothelial cell migration;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016043//cellular component organization;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0021612//facial nerve structural organization;GO:0021636//trigeminal nerve morphogenesis;GO:0021637//trigeminal nerve structural organization;GO:0021649//vestibulocochlear nerve structural organization;GO:0021675//nerve development;GO:0021785//branchiomotor neuron axon guidance;GO:0021828//gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0030154//cell differentiation;GO:0030517//negative regulation of axon extension;GO:0031290//retinal ganglion cell axon guidance;GO:0031532//actin cytoskeleton reorganization;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0035767//endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036486//ventral trunk neural crest cell migration;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0038189//neuropilin signaling pathway;GO:0038190//VEGF-activated neuropilin signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0043542//endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0046718//viral entry into host cell;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0048485//sympathetic nervous system development;GO:0048666//neuron development;GO:0048699//generation of neurons;GO:0048841//regulation of axon extension involved in axon guidance;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048844//artery morphogenesis;GO:0048846//axon extension involved in axon guidance;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050790//regulation of catalytic activity;GO:0050918//positive chemotaxis;GO:0051491//positive regulation of filopodium assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0060301//positive regulation of cytokine activity;GO:0060385//axonogenesis involved in innervation;GO:0060627//regulation of vesicle-mediated transport;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0061441//renal artery morphogenesis;GO:0061549//sympathetic ganglion development;GO:0061551//trigeminal ganglion development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071526//semaphorin-plexin signaling pathway;GO:0071679//commissural neuron axon guidance;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090259//regulation of retinal ganglion cell axon guidance;GO:0097102//endothelial tip cell fate specification;GO:0097374//sensory neuron axon guidance;GO:0097475//motor neuron migration;GO:0097490//sympathetic neuron projection extension;GO:0097491//sympathetic neuron projection guidance;GO:0099173//postsynapse organization;GO:0120035//regulation of plasma membrane bounded cell projection organization;GO:0150018//basal dendrite development;GO:0150020//basal dendrite arborization;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:1901998//toxin transport;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1902336//positive regulation of retinal ganglion cell axon guidance;GO:1902378//VEGF-activated neuropilin signaling pathway involved in axon guidance;GO:1902946//protein localization to early endosome;GO:1903375//facioacoustic ganglion development;GO:1904835//dorsal root ganglion morphogenesis;GO:1905040//otic placode development;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000099256	7.487	8.257	7.025	6.461	6.013	6.741	278	303	189	156	177	171	PRTFDC1	phosphoribosyl transferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23333]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004422//hypoxanthine phosphoribosyltransferase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006166//purine ribonucleoside salvage	--
ENSG00000099260	17.842	17.571	12.862	11.489	13.489	12.09	847	855	455	412	537	424	PALMD	palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0008360//regulation of cell shape	--
ENSG00000099282	9.059	12.505	10.809	11.81	11.393	9.455	320	444	282	309	340	243	TSPAN15	tetraspanin 15 [Source:HGNC Symbol;Acc:HGNC:23298]	-	-	-	-	GO:0005768//endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097197//tetraspanin-enriched microdomain	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0045746//negative regulation of Notch signaling pathway;GO:0051604//protein maturation;GO:0072659//protein localization to plasma membrane	--
ENSG00000099284	29.028	29.742	29.592	27.574	29.67	29.675	1030	1154	835	820	968	866	MACROH2A2	macroH2A.2 histone [Source:HGNC Symbol;Acc:HGNC:14453]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0001740//Barr body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome"	GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0007420//brain development;GO:0007549//dosage compensation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0071169//establishment of protein localization to chromatin;GO:1901837//negative regulation of transcription of nucleolar large rRNA by RNA polymerase I"	--
ENSG00000099290	17.534	16.54	14.777	13.497	13.498	14.481	1479.31	1437.1	996.41	843.22	983.19	915.67	WASHC2A	WASH complex subunit 2A [Source:HGNC Symbol;Acc:HGNC:23416]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18462	GO:0005730//nucleolus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071203//WASH complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:1901981//phosphatidylinositol phosphate binding;GO:1905394//retromer complex binding	"GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0036010//protein localization to endosome;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000099308	2.855	3.167	3.279	2.531	3.248	3.075	352	390	298	231	338	275	MAST3	microtubule associated serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:19036]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000099326	3.828	3.51	4.44	6.166	5.26	5.323	185	183	179	222	217	207	MZF1	myeloid zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13108]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000099330	6.429	8.613	9.622	7.011	7.8	7.769	138	191	155	113	138	122	OCEL1	occludin/ELL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26221]	-	-	-	-	GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle	-	GO:0070830//bicellular tight junction assembly	--
ENSG00000099331	15.879	15.561	15.107	14.722	15.74	14.403	2157	2097	1589	1595	1829	1545	MYO9B	myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016887//ATP hydrolysis activity;GO:0031267//small GTPase binding;GO:0043008//ATP-dependent protein binding;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0048495//Roundabout binding;GO:0051015//actin filament binding	GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0030048//actin filament-based movement;GO:0035023//regulation of Rho protein signal transduction;GO:0035385//Roundabout signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000099337	0.455	0.419	0.388	0.25	0.219	0.255	54	50	34	22	22	22	KCNK6	potassium two pore domain channel subfamily K member 6 [Source:HGNC Symbol;Acc:HGNC:6281]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0003073//regulation of systemic arterial blood pressure;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0060075//regulation of resting membrane potential;GO:0071805//potassium ion transmembrane transport	--
ENSG00000099338	0.178	0.333	0.149	0.151	0.065	0.168	11	9	6	7	3	7	CATSPERG	cation channel sperm associated auxiliary subunit gamma [Source:HGNC Symbol;Acc:HGNC:25243]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0097228//sperm principal piece	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000099341	84.439	90.164	85.692	93.236	87.955	87.6	1995	2130	1506	1638	1741	1513	PSMD8	"proteasome 26S subunit, non-ATPase 8 [Source:HGNC Symbol;Acc:HGNC:9566]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03031;K03031;K03031;K03031;K03031;K03031;K03031;K03031;K03031	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0022624//proteasome accessory complex"	GO:0005515//protein binding	GO:0006508//proteolysis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000099364	7.779	8.709	13.073	9.211	8.755	9.403	631	681	547	559	611	567	FBXL19	F-box and leucine rich repeat protein 19 [Source:HGNC Symbol;Acc:HGNC:25300]	-	-	-	-	GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0032452//histone demethylase activity;GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0016577//histone demethylation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000099365	0.751	0.421	0.345	0.677	0.666	0.975	24	20	13	15	24	28	STX1B	syntaxin 1B [Source:HGNC Symbol;Acc:HGNC:18539]	Organismal Systems;Genetic Information Processing	"Nervous system;Folding, sorting and degradation"	ko04721//Synaptic vesicle cycle;ko04130//SNARE interactions in vesicular transport	K08486;K08486	GO:0005634//nucleus;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031201//SNARE complex;GO:0031594//neuromuscular junction;GO:0048787//presynaptic active zone membrane;GO:0098793//presynapse	GO:0000149//SNARE binding;GO:0005102//signaling receptor binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0001956//positive regulation of neurotransmitter secretion;GO:0006836//neurotransmitter transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0010468//regulation of gene expression;GO:0010807//regulation of synaptic vesicle priming;GO:0010977//negative regulation of neuron projection development;GO:0016079//synaptic vesicle exocytosis;GO:0016081//synaptic vesicle docking;GO:0016192//vesicle-mediated transport;GO:0017157//regulation of exocytosis;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0048278//vesicle docking;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0060025//regulation of synaptic activity;GO:0061669//spontaneous neurotransmitter secretion;GO:0098967//exocytic insertion of neurotransmitter receptor to postsynaptic membrane;GO:1903422//negative regulation of synaptic vesicle recycling;GO:1904050//positive regulation of spontaneous neurotransmitter secretion;GO:1905302//negative regulation of macropinocytosis;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000099377	2.862	3.369	3.631	5.101	4.717	4.059	129	153	109	159	164	133	HSD3B7	"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324]"	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00120//Primary bile acid biosynthesis	K12408;K12408	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047016//cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0035754//B cell chemotaxis	--
ENSG00000099381	6.816	6.228	5.723	6.18	7.821	8.464	702	699	522	565	751	649	SETD1A	"SET domain containing 1A, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:29010]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11422;K11422	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0035097//histone methyltransferase complex;GO:0048188//Set1C/COMPASS complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0032259//methylation;GO:0044648//histone H3-K4 dimethylation;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0097692//histone H3-K4 monomethylation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1902275//regulation of chromatin organization	--
ENSG00000099385	27.017	28.394	28.332	33.597	27.185	24.585	544	576	417	499	470	388	BCL7C	BAF chromatin remodeling complex subunit BCL7C [Source:HGNC Symbol;Acc:HGNC:1006]	-	-	-	-	GO:0000785//chromatin;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	-	GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045596//negative regulation of cell differentiation;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair	--
ENSG00000099399	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB2	MAGE family member B2 [Source:HGNC Symbol;Acc:HGNC:6809]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000099617	1.551	1.939	1.427	1.101	1.86	1.203	78	98	53	41	79	44	EFNA2	ephrin A2 [Source:HGNC Symbol;Acc:HGNC:3222]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031594//neuromuscular junction;GO:0043204//perikaryon	GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0007267//cell-cell signaling;GO:0007411//axon guidance;GO:0021772//olfactory bulb development;GO:0030316//osteoclast differentiation;GO:0046849//bone remodeling;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000099622	107.539	115.465	128.545	156.411	126.88	120.392	2393	2481	1906	2260	2283	1681	CIRBP	cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0030371//translation repressor activity;GO:0070181//small ribosomal subunit rRNA binding	"GO:0009409//response to cold;GO:0009411//response to UV;GO:0017148//negative regulation of translation;GO:0034063//stress granule assembly;GO:0045727//positive regulation of translation;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0048255//mRNA stabilization"	--
ENSG00000099624	56.144	59.832	67.108	94.507	73.723	77.953	922	999	806	1133	1026	926	ATP5F1D	ATP synthase F1 subunit delta [Source:HGNC Symbol;Acc:HGNC:837]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02134;K02134;K02134;K02134;K02134;K02134;K02134;K02134;K02134;K02134;K02134	"GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0110165//cellular anatomical entity"	"GO:0005515//protein binding;GO:0005524//ATP binding;GO:0043531//ADP binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0009060//aerobic respiration;GO:0015986//ATP synthesis coupled proton transport;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0046688//response to copper ion	--
ENSG00000099625	1.668	1.778	2.504	2.304	2.213	2.311	103	100	124	97	137	112.13	CBARP	CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1903170//negative regulation of calcium ion transmembrane transport	--
ENSG00000099715	0.051	0.031	0.015	0	0	0.031	5	3	1	0	0	2	PCDH11Y	protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0061827//sperm head;GO:0097225//sperm midpiece	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007283//spermatogenesis;GO:0030177//positive regulation of Wnt signaling pathway	--
ENSG00000099721	0.078	0.104	0	0	0.062	0	1	2	0	0	1	0	AMELY	amelogenin Y-linked [Source:HGNC Symbol;Acc:HGNC:462]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030345//structural constituent of tooth enamel	GO:0007275//multicellular organism development;GO:0031214//biomineral tissue development	--
ENSG00000099769	9.521	12.193	9.939	13.389	12.617	12.529	407	524	314	418	456	390	IGFALS	insulin like growth factor binding protein acid labile subunit [Source:HGNC Symbol;Acc:HGNC:5468]	Organismal Systems	Endocrine system	"ko04935//Growth hormone synthesis, secretion and action"	K17256	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0042567//insulin-like growth factor ternary complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding	GO:0007155//cell adhesion;GO:0007165//signal transduction	--
ENSG00000099783	66.801	65.17	69.802	65.933	65.244	57.619	2931	2953	2245	2116	2442	1834	HNRNPM	heterogeneous nuclear ribonucleoprotein M [Source:HGNC Symbol;Acc:HGNC:5046]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12887	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0042382//paraspeckles;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0071014//post-mRNA release spliceosomal complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:2000815//regulation of mRNA stability involved in response to oxidative stress"	--
ENSG00000099785	15.374	18.747	17.394	20.445	18.443	16.179	425	484	323	383	441	294	MARCHF2	membrane associated ring-CH-type finger 2 [Source:HGNC Symbol;Acc:HGNC:28038]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006897//endocytosis;GO:0016567//protein ubiquitination;GO:0044790//negative regulation by host of viral release from host cell;GO:0140367//antibacterial innate immune response;GO:0140374//antiviral innate immune response;GO:1905167//positive regulation of lysosomal protein catabolic process	--
ENSG00000099795	66.234	65.896	75.16	92.945	76.157	84.714	735	735	616	764	714	684	NDUFB7	NADH:ubiquinone oxidoreductase subunit B7 [Source:HGNC Symbol;Acc:HGNC:7702]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963;K03963	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000099797	115.785	110.794	134.925	142.884	140.398	142.11	2734	2629	2352	2494	2799	2440	TECR	"trans-2,3-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:4551]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10258;K10258;K10258;K10258	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0102758//very-long-chain enoyl-CoA reductase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0030497//fatty acid elongation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process	--
ENSG00000099800	23.817	27.125	27.381	30.624	25.782	24.517	542	609	469	534	527	465	TIMM13	translocase of inner mitochondrial membrane 13 [Source:HGNC Symbol;Acc:HGNC:11816]	-	-	-	-	GO:0001650//fibrillar center;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000099804	33.452	39.56	36.349	35.64	36.37	30.419	972	1157	780	760	898	641	CDC34	"cell division cycle 34, ubiqiutin conjugating enzyme [Source:HGNC Symbol;Acc:HGNC:1734]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K02207	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0006270//DNA replication initiation;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0035458//cellular response to interferon-beta;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0051301//cell division;GO:0070848//response to growth factor;GO:0070936//protein K48-linked ubiquitination;GO:0090261//positive regulation of inclusion body assembly	--
ENSG00000099810	9.083	8.181	7.431	9.487	7.953	9.209	761	661	498	481.54	569	535	MTAP	methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K00772;K00772	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004645//1,4-alpha-oligoglucan phosphorylase activity;GO:0004731//purine-nucleoside phosphorylase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0017061//S-methyl-5-thioadenosine phosphorylase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006166//purine ribonucleoside salvage;GO:0009116//nucleoside metabolic process;GO:0019509//L-methionine salvage from methylthioadenosine	--
ENSG00000099812	0.217	0.482	0.113	0.632	0.613	0.482	13	29	5	28	31	21	MISP	mitotic spindle positioning [Source:HGNC Symbol;Acc:HGNC:27000]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031616//spindle pole centrosome;GO:0043231//intracellular membrane-bounded organelle;GO:1905721//mitotic spindle astral microtubule end	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0000132//establishment of mitotic spindle orientation;GO:0007049//cell cycle;GO:0016477//cell migration;GO:0051301//cell division;GO:0051640//organelle localization;GO:0051660//establishment of centrosome localization;GO:0090307//mitotic spindle assembly;GO:1904776//regulation of protein localization to cell cortex	--
ENSG00000099814	9.429	8.939	10.368	10.005	9.966	10.704	1309	1247	1063	1029	1169	1081	CEP170B	centrosomal protein 170B [Source:HGNC Symbol;Acc:HGNC:20362]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding	-	--
ENSG00000099817	80.693	79.941	84.684	98.289	91.736	89.446	2266	2327	1807	2082	2200	1865	POLR2E	"RNA polymerase II, I and III subunit E [Source:HGNC Symbol;Acc:HGNC:9192]"	Human Diseases;Organismal Systems;Genetic Information Processing	Neurodegenerative disease;Immune system;Transcription	ko05016//Huntington disease;ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03013;K03013;K03013	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol;GO:0055029//nuclear DNA-directed RNA polymerase complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex"	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0050821//protein stabilization"	--
ENSG00000099821	9.09	9.655	12.471	11.218	11.615	11.035	711	753	713	643	756	628	POLRMT	RNA polymerase mitochondrial [Source:HGNC Symbol;Acc:HGNC:9200]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0032991//protein-containing complex;GO:0034245//mitochondrial DNA-directed RNA polymerase complex;GO:0042645//mitochondrial nucleoid	GO:0001018//mitochondrial promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0043565//sequence-specific DNA binding	"GO:0006351//transcription, DNA-templated;GO:0006390//mitochondrial transcription"	--
ENSG00000099822	1.198	1.725	2.271	2.417	2.67	2.151	85	123	119	127	160	111	HCN2	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 [Source:HGNC Symbol;Acc:HGNC:4846]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04024//cAMP signaling pathway;ko04929//GnRH secretion	K04955;K04955	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098855//HCN channel complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0030552//cAMP binding;GO:0042802//identical protein binding	GO:0003254//regulation of membrane depolarization;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0007267//cell-cell signaling;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071321//cellular response to cGMP;GO:0071805//potassium ion transmembrane transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098719//sodium ion import across plasma membrane;GO:0098907//regulation of SA node cell action potential;GO:1990573//potassium ion import across plasma membrane;GO:2001257//regulation of cation channel activity	--
ENSG00000099834	0.282	0.792	0.451	0.437	0.475	0.697	19	19	13	13	16	9	CDHR5	cadherin related family member 5 [Source:HGNC Symbol;Acc:HGNC:7521]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection;GO:0044214//spanning component of plasma membrane;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0050839//cell adhesion molecule binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030154//cell differentiation;GO:0032532//regulation of microvillus length;GO:0090675//intermicrovillar adhesion	--
ENSG00000099840	0.507	0.586	0.679	1.068	0.419	1.036	10	11	9	16	7	15	IZUMO4	IZUMO family member 4 [Source:HGNC Symbol;Acc:HGNC:26950]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus	-	-	--
ENSG00000099849	4.241	5.739	6.133	6.087	5.727	6.694	150	209	165	141	171	167	RASSF7	Ras association domain family member 7 [Source:HGNC Symbol;Acc:HGNC:1166]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000099860	28.328	28.988	20.488	18.182	21.174	18.414	793	823	425	383	480	381	GADD45B	growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death;Signal transduction;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04064//NF-kappa B signaling pathway;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05224//Breast cancer;ko05226//Gastric cancer;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0051726//regulation of cell cycle;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000099864	42.214	45.776	37.376	45.953	46.43	42.245	2453	2619	1605	1948	2186	1735	PALM	paralemmin [Source:HGNC Symbol;Acc:HGNC:8594]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031527//filopodium membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0044309//neuron spine;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0031750//D3 dopamine receptor binding	GO:0007010//cytoskeleton organization;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008104//protein localization;GO:0008360//regulation of cell shape;GO:0051491//positive regulation of filopodium assembly;GO:0060074//synapse maturation;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0071257//cellular response to electrical stimulus;GO:0072659//protein localization to plasma membrane	--
ENSG00000099866	0.037	0	0.038	0	0	0	1	0	1	0	0	0	MADCAM1	mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04672//Intestinal immune network for IgA production	K06779;K06779	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0098640//integrin binding involved in cell-matrix adhesion	GO:0002687//positive regulation of leukocyte migration;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0034113//heterotypic cell-cell adhesion;GO:0043113//receptor clustering;GO:0050901//leukocyte tethering or rolling;GO:2000403//positive regulation of lymphocyte migration	--
ENSG00000099875	32.014	29.58	34.52	38.166	33.876	38.365	1620	1630	1330	1492	1559	1408	MKNK2	MAPK interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:7111]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signal transduction;Endocrine system;Signal transduction	ko04010//MAPK signaling pathway;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway	K04372;K04372;K04372	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0016605//PML body	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030097//hemopoiesis;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:0071243//cellular response to arsenic-containing substance;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000099889	22.025	24.1	28.246	28.077	29.265	35.339	1446	1574	1365	1361	1588	1665	ARVCF	ARVCF delta catenin family member [Source:HGNC Symbol;Acc:HGNC:728]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0098609//cell-cell adhesion	--
ENSG00000099899	11.702	11.389	12.743	12.151	11.783	12.546	612.32	643.16	492.61	502.83	564.88	523.88	TRMT2A	tRNA methyltransferase 2 homolog A [Source:HGNC Symbol;Acc:HGNC:24974]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity	GO:0001510//RNA methylation;GO:0006396//RNA processing;GO:0032259//methylation	--
ENSG00000099901	33.033	37.725	40.575	32.857	30.895	28.554	651.68	730.84	576.39	464.17	490.12	404.12	RANBP1	RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis	K15306;K15306	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol	GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding	GO:0006913//nucleocytoplasmic transport;GO:0007051//spindle organization;GO:0007165//signal transduction;GO:0046604//positive regulation of mitotic centrosome separation;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000099904	8.956	7.31	7.334	10.363	9.151	9.251	493	493	378	425	519	439	ZDHHC8	zinc finger DHHC-type palmitoyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:18474]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0007626//locomotory behavior;GO:0010875//positive regulation of cholesterol efflux;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0034380//high-density lipoprotein particle assembly;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000099910	22.149	27.679	28.419	26.946	27.266	30.086	988	1011	853	781	913	846	KLHL22	kelch like family member 22 [Source:HGNC Symbol;Acc:HGNC:25888]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005827//polar microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0071889//14-3-3 protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0006513//protein monoubiquitination;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0010507//negative regulation of autophagy;GO:0016567//protein ubiquitination;GO:0030307//positive regulation of cell growth;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051301//cell division;GO:0071233//cellular response to leucine;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000099917	15.121	15.762	17.05	17.969	18.605	16.15	992	1026	662	793	993	710	MED15	mediator complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:14248]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000099937	0.08	0.087	0	0.03	0	0	3	4	0	1	0	0	SERPIND1	serpin family D member 1 [Source:HGNC Symbol;Acc:HGNC:4838]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03912	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity	GO:0006935//chemotaxis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000099940	18.227	19.873	22.299	20.03	19.844	17.375	1131	971	749	723	876.61	748	SNAP29	synaptosome associated protein 29 [Source:HGNC Symbol;Acc:HGNC:11133]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04140//Autophagy - animal;ko04130//SNARE interactions in vesicular transport	K08509;K08509	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0020018//ciliary pocket membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0035577//azurophil granule membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0098793//presynapse	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006887//exocytosis;GO:0006903//vesicle targeting;GO:0006906//vesicle fusion;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016082//synaptic vesicle priming;GO:0016240//autophagosome membrane docking;GO:0030030//cell projection organization;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0060271//cilium assembly;GO:0061025//membrane fusion;GO:0097352//autophagosome maturation	--
ENSG00000099942	11.868	12.31	12.611	12.269	12.466	12.776	1315	1371	1032	1007	1167	1030	CRKL	"CRK like proto-oncogene, adaptor protein [Source:HGNC Symbol;Acc:HGNC:2363]"	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cancer: overview;Immune system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04910//Insulin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04012//ErbB signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma"	K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0098890//extrinsic component of postsynaptic membrane	GO:0001784//phosphotyrosine residue binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001558//regulation of cell growth;GO:0001568//blood vessel development;GO:0001655//urogenital system development;GO:0001764//neuron migration;GO:0001783//B cell apoptotic process;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002685//regulation of leukocyte migration;GO:0003151//outflow tract morphogenesis;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0007265//Ras protein signal transduction;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007389//pattern specification process;GO:0007416//synapse assembly;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008584//male gonad development;GO:0009887//animal organ morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030010//establishment of cell polarity;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0035556//intracellular signal transduction;GO:0035685//helper T cell diapedesis;GO:0038026//reelin-mediated signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0048384//retinoic acid receptor signaling pathway;GO:0048538//thymus development;GO:0050773//regulation of dendrite development;GO:0050852//T cell receptor signaling pathway;GO:0060017//parathyroid gland development;GO:0060326//cell chemotaxis;GO:0060465//pharynx development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071466//cellular response to xenobiotic stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071774//response to fibroblast growth factor;GO:0086100//endothelin receptor signaling pathway;GO:0090630//activation of GTPase activity;GO:0095500//acetylcholine receptor signaling pathway;GO:0098749//cerebellar neuron development;GO:0098761//cellular response to interleukin-7;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1903977//positive regulation of glial cell migration;GO:1904393//regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1904888//cranial skeletal system development;GO:2000404//regulation of T cell migration	--
ENSG00000099949	12.703	12.859	15.436	14.501	15.776	14.446	1062	1085	991	828	1113	820	LZTR1	leucine zipper like transcription regulator 1 [Source:HGNC Symbol;Acc:HGNC:6742]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0016567//protein ubiquitination;GO:0046580//negative regulation of Ras protein signal transduction	--
ENSG00000099953	12.596	14.881	10.267	13.374	15.113	13.332	589	682	354	460	596	452	MMP11	matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157]	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0071711//basement membrane organization	--
ENSG00000099954	0.07	0.139	0.122	0.142	0.035	0.11	14	29	18	21	6	16	CECR2	CECR2 histone acetyl-lysine reader [Source:HGNC Symbol;Acc:HGNC:1840]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0031010//ISWI-type complex;GO:0090537//CERF complex	GO:0005515//protein binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0001842//neural fold formation;GO:0001843//neural tube closure;GO:0006309//apoptotic DNA fragmentation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007010//cytoskeleton organization;GO:0007338//single fertilization;GO:0016192//vesicle-mediated transport;GO:0021915//neural tube development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0061640//cytoskeleton-dependent cytokinesis;GO:0090102//cochlea development;GO:0097194//execution phase of apoptosis	--
ENSG00000099956	52.794	51.909	56.065	57.881	51.833	57.154	1658.9	1721.69	1365.34	1357	1443.84	1313	SMARCB1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [Source:HGNC Symbol;Acc:HGNC:11103]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11648;K11648	GO:0000228//nuclear chromosome;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070603//SWI/SNF superfamily-type complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030957//Tat protein binding;GO:0031492//nucleosomal DNA binding;GO:0042802//identical protein binding	GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0001824//blastocyst development;GO:0001835//blastocyst hatching;GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0015074//DNA integration;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030154//cell differentiation;GO:0039692//single stranded viral RNA replication via double stranded DNA intermediate;GO:0043923//positive regulation by host of viral transcription;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0070316//regulation of G0 to G1 transition;GO:0090240//positive regulation of histone H4 acetylation;GO:1900110//negative regulation of histone H3-K9 dimethylation;GO:1900113//negative regulation of histone H3-K9 trimethylation;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1902459//positive regulation of stem cell population maintenance;GO:1902661//positive regulation of glucose mediated signaling pathway;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair	--
ENSG00000099957	0.293	0.141	0.336	0.218	0.737	0.528	16	8	12	7	29	12	P2RX6	purinergic receptor P2X 6 [Source:HGNC Symbol;Acc:HGNC:8538]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K05221;K05221	GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098978//glutamatergic synapse;GO:0099060//integral component of postsynaptic specialization membrane	GO:0001614//purinergic nucleotide receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005216//ion channel activity;GO:0005524//ATP binding;GO:0015267//channel activity;GO:0044877//protein-containing complex binding	GO:0006811//ion transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0060079//excitatory postsynaptic potential;GO:0098655//cation transmembrane transport	--
ENSG00000099958	0.109	0.356	0.225	0.269	0.286	0.249	3.1	10.31	3.66	4	5.16	4	DERL3	derlin 3 [Source:HGNC Symbol;Acc:HGNC:14236]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13989	GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0051787//misfolded protein binding;GO:1990381//ubiquitin-specific protease binding	"GO:0006950//response to stress;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000099960	0.669	0.333	0.451	0.705	1.187	1.12	32	16	16	25	48	39	SLC7A4	solute carrier family 7 member 4 [Source:HGNC Symbol;Acc:HGNC:11062]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:1990822//basic amino acid transmembrane transport	--
ENSG00000099968	102.524	107.795	105.1	98.221	99.23	113.497	6729	7030	5166	4672	5498	5420	BCL2L13	BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]	Cellular Processes;Human Diseases	Transport and catabolism;Infectious disease: bacterial	ko04137//Mitophagy - animal;ko05134//Legionellosis	K15485;K15485	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process	--
ENSG00000099974	1.218	0.409	0.604	1.033	0.568	0.663	39.97	13.49	14.64	25.12	15.76	15.84	DDTL	D-dopachrome tautomerase like [Source:HGNC Symbol;Acc:HGNC:33446]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0016829//lyase activity;GO:0050178//phenylpyruvate tautomerase activity	-	--
ENSG00000099977	43.118	39.82	45.451	52.385	47.049	50.763	507.03	469.51	393.4	454.84	466.24	434.16	DDT	D-dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2732]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0004167//dopachrome isomerase activity;GO:0005126//cytokine receptor binding;GO:0016829//lyase activity;GO:0033981//D-dopachrome decarboxylase activity;GO:0050178//phenylpyruvate tautomerase activity	GO:0010760//negative regulation of macrophage chemotaxis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042438//melanin biosynthetic process;GO:0050729//positive regulation of inflammatory response;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000099984	1.174	1.59	2.268	1.327	1.273	1.478	27.81	32.35	35.65	19.1	22.16	20.9	GSTT2	glutathione S-transferase theta 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:4642]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004364//glutathione transferase activity;GO:0005515//protein binding	GO:0006749//glutathione metabolic process	--
ENSG00000099985	0	0	0	0	0	0	0	0	0	0	0	0	OSM	oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signaling molecules and interaction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05418;K05418;K05418	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005147//oncostatin-M receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0002675//positive regulation of acute inflammatory response;GO:0006955//immune response;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010646//regulation of cell communication;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0023051//regulation of signaling;GO:0032740//positive regulation of interleukin-17 production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0040008//regulation of growth;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043410//positive regulation of MAPK cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046888//negative regulation of hormone secretion;GO:0050729//positive regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:1902036//regulation of hematopoietic stem cell differentiation	--
ENSG00000099991	26.392	27.213	27.203	22.119	24.201	23.987	3417	3420	2547	2113	2556	2081	CABIN1	calcineurin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:24187]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0031491//nucleosome binding	GO:0006325//chromatin organization;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007166//cell surface receptor signaling pathway;GO:0043086//negative regulation of catalytic activity	--
ENSG00000099992	6.457	6.912	7.749	7.35	5.616	6.344	264.1	284.17	225.58	222.69	194.13	188.69	TBC1D10A	TBC1 domain family member 10A [Source:HGNC Symbol;Acc:HGNC:23609]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0045296//cadherin binding	"GO:0042147//retrograde transport, endosome to Golgi;GO:0045862//positive regulation of proteolysis;GO:0090630//activation of GTPase activity;GO:0097202//activation of cysteine-type endopeptidase activity"	--
ENSG00000099994	4.332	5.141	3.21	1.642	1.925	1.984	285	340	156	80	107	95	SUSD2	sushi domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30667]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0051782//negative regulation of cell division;GO:1902807//negative regulation of cell cycle G1/S phase transition	--
ENSG00000099995	22.876	21.333	23.925	24.805	26.753	20.661	2074.96	2153.89	1669.95	1771	2070	1538	SF3A1	splicing factor 3a subunit 1 [Source:HGNC Symbol;Acc:HGNC:10765]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12825	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome;GO:1903241//U2-type prespliceosome assembly"	--
ENSG00000099998	3.265	3.645	2.206	1.379	1.588	0.929	158	105	75	49	63	34	GGT5	gamma-glutamyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:4260]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0000048//peptidyltransferase activity;GO:0002951//leukotriene-C(4) hydrolase;GO:0008233//peptidase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0036374//glutathione hydrolase activity;GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0103068//leukotriene C4 gamma-glutamyl transferase activity	GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006751//glutathione catabolic process;GO:0006954//inflammatory response;GO:0019370//leukotriene biosynthetic process;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000099999	4.262	5.126	5.084	4.672	4.498	4.894	205.58	240.26	181.37	157.66	174.36	165.34	RNF215	ring finger protein 215 [Source:HGNC Symbol;Acc:HGNC:33434]	-	-	-	-	GO:0005768//endosome;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017119//Golgi transport complex	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006623//protein targeting to vacuole;GO:0006896//Golgi to vacuole transport;GO:0016567//protein ubiquitination	--
ENSG00000100003	37.596	42.559	38.474	44.048	41.08	34.468	1923	2170	1585	1703	1816	1336	SEC14L2	SEC14 like lipid binding 2 [Source:HGNC Symbol;Acc:HGNC:10699]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0008431//vitamin E binding	"GO:0045540//regulation of cholesterol biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000100012	0	0	0	0	0	0	0	0	0	0	0	0	SEC14L3	SEC14 like lipid binding 3 [Source:HGNC Symbol;Acc:HGNC:18655]	-	-	-	-	GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0070062//extracellular exosome	GO:0008289//lipid binding	-	--
ENSG00000100014	13.917	11.167	11.019	8.317	8.769	10.172	1677	1418	993	773	971	923.96	SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1 like [Source:HGNC Symbol;Acc:HGNC:29022]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005921//gap junction;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0031941//filamentous actin	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0051301//cell division	--
ENSG00000100023	11.474	12.454	12.821	12.512	13.431	11.842	874.38	952.53	704.8	697.27	868.62	661.42	PPIL2	peptidylprolyl isomerase like 2 [Source:HGNC Symbol;Acc:HGNC:9261]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10598	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005796//Golgi lumen;GO:0005886//plasma membrane	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016853//isomerase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0016567//protein ubiquitination;GO:0072659//protein localization to plasma membrane	--
ENSG00000100024	0.031	0.09	0	0	0.109	0.087	2	4	0	0	6	5	UPB1	beta-ureidopropionase 1 [Source:HGNC Symbol;Acc:HGNC:16297]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism;Metabolism of other amino acids;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism;ko00410//beta-Alanine metabolism;ko00770//Pantothenate and CoA biosynthesis	K01431;K01431;K01431;K01431;K01431	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003837//beta-ureidopropionase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0042803//protein homodimerization activity"	GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0006248//CMP catabolic process;GO:0006249//dCMP catabolic process;GO:0006807//nitrogen compound metabolic process;GO:0019482//beta-alanine metabolic process;GO:0019483//beta-alanine biosynthetic process;GO:0033396//beta-alanine biosynthetic process via 3-ureidopropionate;GO:0046050//UMP catabolic process;GO:0046079//dUMP catabolic process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0051260//protein homooligomerization;GO:0051289//protein homotetramerization	--
ENSG00000100027	1.906	4.113	2.686	1.547	3.129	2.344	162.62	159.47	84.2	77.73	90.38	56.58	YPEL1	yippee like 1 [Source:HGNC Symbol;Acc:HGNC:12845]	-	-	-	-	GO:0005634//nucleus	GO:0046872//metal ion binding	-	--
ENSG00000100028	27.733	27.292	28.187	27.955	27.018	25.499	1993.75	1972.17	1496.66	1488.69	1641.02	1333.84	SNRPD3	small nuclear ribonucleoprotein D3 polypeptide [Source:HGNC Symbol;Acc:HGNC:11160]	Human Diseases;Genetic Information Processing	Immune disease;Transcription	ko05322//Systemic lupus erythematosus;ko03040//Spliceosome	K11088;K11088	GO:0000243//commitment complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005683//U7 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0097526//spliceosomal tri-snRNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0070034//telomerase RNA binding;GO:0071208//histone pre-mRNA DCP binding;GO:0071209//U7 snRNA binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006479//protein methylation;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000100029	25.013	28.95	26.801	30.574	29.474	26.172	1148	1357	923	1061	1154	871	PES1	pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030687//preribosome, large subunit precursor;GO:0043229//intracellular organelle;GO:0070545//PeBoW complex"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0008283//cell population proliferation;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0051726//regulation of cell cycle"	--
ENSG00000100030	42.675	42.264	42.268	36.533	37.836	40.984	3889	3760	2837	2506	2893	2651	MAPK1	mitogen-activated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:6871]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Signal transduction;Cancer: overview;Immune system;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Immune system;Nervous system;Cancer: specific types;Circulatory system;Cancer: specific types;Infectious disease: parasitic;Cellular community - eukaryotes;Cell growth and death;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Signal transduction;Nervous system;Nervous system;Nervous system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Cancer: overview;Immune system;Signal transduction;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cellular community - eukaryotes;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Endocrine and metabolic disease;Excretory system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko04360//Axon guidance;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05224//Breast cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04350//TGF-beta signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05133//Pertussis;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko04930//Type II diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0031143//pseudopodium;GO:0035578//azurophil granule lumen;GO:0045202//synapse;GO:0072686//mitotic spindle;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019902//phosphatase binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007507//heart development;GO:0007611//learning or memory;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0014032//neural crest cell development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019858//cytosine metabolic process;GO:0030278//regulation of ossification;GO:0030641//regulation of cellular pH;GO:0030878//thyroid gland development;GO:0031647//regulation of protein stability;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032496//response to lipopolysaccharide;GO:0032872//regulation of stress-activated MAPK cascade;GO:0033598//mammary gland epithelial cell proliferation;GO:0034198//cellular response to amino acid starvation;GO:0034614//cellular response to reactive oxygen species;GO:0035094//response to nicotine;GO:0035556//intracellular signal transduction;GO:0038127//ERBB signaling pathway;GO:0042473//outer ear morphogenesis;GO:0043330//response to exogenous dsRNA;GO:0045596//negative regulation of cell differentiation;GO:0048538//thymus development;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0051493//regulation of cytoskeleton organization;GO:0051973//positive regulation of telomerase activity;GO:0060020//Bergmann glial cell differentiation;GO:0060291//long-term synaptic potentiation;GO:0060324//face development;GO:0060425//lung morphogenesis;GO:0060440//trachea formation;GO:0060716//labyrinthine layer blood vessel development;GO:0061308//cardiac neural crest cell development involved in heart development;GO:0070371//ERK1 and ERK2 cascade;GO:0070849//response to epidermal growth factor;GO:0071276//cellular response to cadmium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0072584//caveolin-mediated endocytosis;GO:0090170//regulation of Golgi inheritance;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0120041//positive regulation of macrophage proliferation;GO:1903351//cellular response to dopamine;GO:1904355//positive regulation of telomere capping;GO:2000641//regulation of early endosome to late endosome transport	--
ENSG00000100031	16.345	17.448	13.141	14.573	15.925	11.247	473.62	531.07	349.72	364	422	240.29	GGT1	gamma-glutamyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4250]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0000048//peptidyltransferase activity;GO:0002951//leukotriene-C(4) hydrolase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0036374//glutathione hydrolase activity;GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0103068//leukotriene C4 gamma-glutamyl transferase activity	GO:0002682//regulation of immune system process;GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process;GO:0006536//glutamate metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006751//glutathione catabolic process;GO:0007283//spermatogenesis;GO:0019344//cysteine biosynthetic process;GO:0031179//peptide modification;GO:0031638//zymogen activation;GO:0050727//regulation of inflammatory response;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000100033	10.889	11.657	11.758	13.778	11.809	10.822	463.87	536.25	366.37	427.98	449.88	357.33	PRODH	proline dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:9453]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00318;K00318	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0004657//proline dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0071949//FAD binding	GO:0006560//proline metabolic process;GO:0006562//proline catabolic process;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010133//proline catabolic process to glutamate;GO:0010942//positive regulation of cell death;GO:0019470//4-hydroxyproline catabolic process	--
ENSG00000100034	7.874	7.697	8.597	10.932	8.866	8.48	737	786	626	690	783	619	PPM1F	"protein phosphatase, Mg2+/Mn2+ dependent 1F [Source:HGNC Symbol;Acc:HGNC:19388]"	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0006469//negative regulation of protein kinase activity;GO:0006470//protein dephosphorylation;GO:0006915//apoptotic process;GO:0010628//positive regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010811//positive regulation of cell-substrate adhesion;GO:0016576//histone dephosphorylation;GO:0030335//positive regulation of cell migration;GO:0032880//regulation of protein localization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045927//positive regulation of growth;GO:0050921//positive regulation of chemotaxis;GO:0051224//negative regulation of protein transport;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0070262//peptidyl-serine dephosphorylation;GO:0071466//cellular response to xenobiotic stimulus;GO:0097193//intrinsic apoptotic signaling pathway;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin"	--
ENSG00000100036	7.162	6.964	8.068	9.996	10.875	11.423	384	375	316.61	397	491	445	SLC35E4	solute carrier family 35 member E4 [Source:HGNC Symbol;Acc:HGNC:17058]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0055085//transmembrane transport	--
ENSG00000100038	13.201	9.72	13.679	14.301	11.299	14.272	505	474	382	429	445	475	TOP3B	DNA topoisomerase III beta [Source:HGNC Symbol;Acc:HGNC:11993]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K03165;K03165	GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0140225//DNA topoisomerase III-beta-TDRD3 complex	"GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003916//DNA topoisomerase activity;GO:0003917//DNA topoisomerase type I (single strand cut, ATP-independent) activity;GO:0005515//protein binding;GO:0016853//isomerase activity"	GO:0006265//DNA topological change;GO:0007059//chromosome segregation	--
ENSG00000100053	0.056	0.056	0	0	0.067	0	1	1	0	0	1	0	CRYBB3	crystallin beta B3 [Source:HGNC Symbol;Acc:HGNC:2400]	-	-	-	-	-	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000100055	0	0	0	0.042	0.037	0	0	0	0	2	2	0	CYTH4	cytohesin 4 [Source:HGNC Symbol;Acc:HGNC:9505]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway	K18441;K18441;K18441;K18441;K18441	GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034451//centriolar satellite;GO:0045171//intercellular bridge	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000100056	6.561	6.725	8.596	7.967	6.8	6.645	401	437	382	342	378	284	ESS2	ess-2 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:16817]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing"	--
ENSG00000100060	0.349	0.469	0.618	0.245	0.651	0.93	15	13	14	6	15	11	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7038]	Human Diseases;Environmental Information Processing;Metabolism	Infectious disease: viral;Signal transduction;Glycan biosynthesis and metabolism	ko05165//Human papillomavirus infection;ko04330//Notch signaling pathway;ko00514//Other types of O-glycan biosynthesis	K05948;K05948;K05948	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding	GO:0001825//blastocyst formation;GO:0002315//marginal zone B cell differentiation;GO:0007389//pattern specification process;GO:0008593//regulation of Notch signaling pathway;GO:0032092//positive regulation of protein binding;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000100065	4.828	3.688	5.137	6.532	5.332	4.778	245	267	179	263	267	221	CARD10	caspase recruitment domain family member 10 [Source:HGNC Symbol;Acc:HGNC:16422]	Environmental Information Processing	Signal transduction	ko04064//NF-kappa B signaling pathway	K20912	GO:0005737//cytoplasm;GO:0032449//CBM complex	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0050700//CARD domain binding	GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0042981//regulation of apoptotic process;GO:0065003//protein-containing complex assembly;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:1900182//positive regulation of protein localization to nucleus	--
ENSG00000100075	34.881	38.585	39.304	47.529	43.114	40.492	1118	1241	929	1126	1167	945	SLC25A1	solute carrier family 25 member 1 [Source:HGNC Symbol;Acc:HGNC:10979]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0015137//citrate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0071913//citrate secondary active transmembrane transporter activity	GO:0006094//gluconeogenesis;GO:0006843//mitochondrial citrate transmembrane transport;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0055085//transmembrane transport	--
ENSG00000100077	1.604	0.988	1.203	0.835	2.386	1.293	275	191	171	119	190	181	GRK3	G protein-coupled receptor kinase 3 [Source:HGNC Symbol;Acc:HGNC:290]	Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Sensory system;Transport and catabolism;Immune system;Nervous system;Substance dependence;Signal transduction	ko04740//Olfactory transduction;ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko04724//Glutamatergic synapse;ko05032//Morphine addiction;ko04340//Hedgehog signaling pathway	K00910;K00910;K00910;K00910;K00910;K00910	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0047696//beta-adrenergic receptor kinase activity	GO:0002029//desensitization of G protein-coupled receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0031623//receptor internalization;GO:0043170//macromolecule metabolic process	--
ENSG00000100078	0	0.037	0.151	0.125	0.132	0.025	0	2	6	5	6	1	PLA2G3	phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0055037//recycling endosome	GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0001675//acrosome assembly;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0007288//sperm axoneme assembly;GO:0010629//negative regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010976//positive regulation of neuron projection development;GO:0019372//lipoxygenase pathway;GO:0030030//cell projection organization;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0032308//positive regulation of prostaglandin secretion;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0042116//macrophage activation;GO:0043303//mast cell degranulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0048468//cell development;GO:0048469//cell maturation;GO:0050482//arachidonic acid secretion;GO:0060271//cilium assembly;GO:0060376//positive regulation of mast cell differentiation;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900222//negative regulation of amyloid-beta clearance;GO:1903595//positive regulation of histamine secretion by mast cell;GO:2001135//regulation of endocytic recycling	--
ENSG00000100079	0	0	0	0	0	0	0	0	0	0	0	0	LGALS2	galectin 2 [Source:HGNC Symbol;Acc:HGNC:6562]	-	-	-	-	GO:0005737//cytoplasm;GO:1990724//galectin complex	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0050729//positive regulation of inflammatory response;GO:0098609//cell-cell adhesion	--
ENSG00000100083	14.537	16.238	16.831	18.113	20.456	17.294	702	732	594	637	737	583	GGA1	"golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17842]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12404	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	"GO:0006886//intracellular protein transport;GO:0006893//Golgi to plasma membrane transport;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0034394//protein localization to cell surface;GO:0042147//retrograde transport, endosome to Golgi;GO:0043001//Golgi to plasma membrane protein transport;GO:0045732//positive regulation of protein catabolic process;GO:1901998//toxin transport;GO:1903441//protein localization to ciliary membrane"	--
ENSG00000100084	11.791	11.397	10.928	10.38	10.62	12.279	991.24	963	678.52	646.37	754.28	751.05	HIRA	histone cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:4916]	-	-	-	-	GO:0000417//HIR complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0001649//osteoblast differentiation;GO:0006325//chromatin organization;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007369//gastrulation;GO:0009653//anatomical structure morphogenesis;GO:0042692//muscle cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000100092	1.927	1.473	2.101	1.227	1.102	2.154	99.18	81.99	65.67	50.29	50.12	87	SH3BP1	SH3 domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10824]	-	-	-	-	GO:0000145//exocyst;GO:0001891//phagocytic cup;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0030215//semaphorin receptor binding	"GO:0006909//phagocytosis;GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0016477//cell migration;GO:0030834//regulation of actin filament depolymerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0034329//cell junction assembly;GO:0035020//regulation of Rac protein signal transduction;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0043547//positive regulation of GTPase activity;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0071526//semaphorin-plexin signaling pathway"	--
ENSG00000100095	0.401	0.331	0.159	0.255	0.104	0.103	36	30	16	15	9	5	SEZ6L	seizure related 6 homolog like [Source:HGNC Symbol;Acc:HGNC:10763]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000100097	102.525	99.157	103.895	78.316	75.8	70.63	1123	1092	841	636	702	564	LGALS1	galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1990724//galectin complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043236//laminin binding	GO:0002317//plasma cell differentiation;GO:0006915//apoptotic process;GO:0031295//T cell costimulation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045445//myoblast differentiation;GO:0046598//positive regulation of viral entry into host cell;GO:0050729//positive regulation of inflammatory response;GO:0098609//cell-cell adhesion	--
ENSG00000100099	18.274	17.684	16.371	14.726	15.583	16.765	1368	1390	941	845	1026	939	HPS4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 [Source:HGNC Symbol;Acc:HGNC:15844]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031085//BLOC-3 complex;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0042827//platelet dense granule	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity	GO:0006605//protein targeting;GO:0006996//organelle organization;GO:0007040//lysosome organization;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0016192//vesicle-mediated transport;GO:0030318//melanocyte differentiation;GO:0046907//intracellular transport;GO:0048075//positive regulation of eye pigmentation;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000100100	8.53	9.832	8.91	6.946	7.233	5.346	422	495	330	257	306	195	PIK3IP1	phosphoinositide-3-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24942]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding	GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity	--
ENSG00000100101	0	0.01	0	0.013	0.052	0	0	1.06	0	0.97	4.43	0	NOL12	novel transcript	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding	-	--
ENSG00000100104	4.755	5.204	4.735	4.771	4.129	5.488	396.51	436.19	291.61	294.69	290.86	332.97	SRRD	SRR1 domain containing [Source:HGNC Symbol;Acc:HGNC:33910]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	GO:0006783//heme biosynthetic process;GO:0007017//microtubule-based process;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0070453//regulation of heme biosynthetic process	--
ENSG00000100105	16.832	18.344	17.183	18.432	17.781	14.718	1128	1249	850	930	1019	744	PATZ1	POZ/BTB and AT hook containing zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13071]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0010468//regulation of gene expression;GO:0010596//negative regulation of endothelial cell migration;GO:0030217//T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	ZBTB
ENSG00000100106	41.793	39.602	41.044	52.854	51.763	52.674	2099	1992.03	1560	2043.11	2192.94	1898	TRIOBP	TRIO and F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:17009]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0120044//stereocilium base	GO:0003779//actin binding;GO:0031267//small GTPase binding;GO:0031625//ubiquitin protein ligase binding;GO:0045159//myosin II binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0007605//sensory perception of sound;GO:0030047//actin modification;GO:0051016//barbed-end actin filament capping;GO:0051301//cell division;GO:0060088//auditory receptor cell stereocilium organization;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000100109	13.846	12.477	13.161	12.307	12.335	13.64	886.49	815.81	645.39	595.31	602.14	646.03	TFIP11	tuftelin interacting protein 11 [Source:HGNC Symbol;Acc:HGNC:17165]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0031012//extracellular matrix;GO:0071008//U2-type post-mRNA release spliceosomal complex;GO:0071013//catalytic step 2 spliceosome"	GO:0003676//nucleic acid binding;GO:0005515//protein binding	"GO:0000390//spliceosomal complex disassembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006807//nitrogen compound metabolic process;GO:0008380//RNA splicing;GO:0031214//biomineral tissue development;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031848//protection from non-homologous end joining at telomere;GO:0032091//negative regulation of protein binding;GO:0043170//macromolecule metabolic process;GO:0044238//primary metabolic process;GO:1904876//negative regulation of DNA ligase activity;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000100116	13.902	14.488	16.751	23.272	19.111	20.53	416	388	319	457	441	401	GCAT	glycine C-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:4188]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism"	K00639;K00639	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016607//nuclear speck	GO:0003824//catalytic activity;GO:0008890//glycine C-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006520//cellular amino acid metabolic process;GO:0006567//threonine catabolic process;GO:0009058//biosynthetic process;GO:0019518//L-threonine catabolic process to glycine	--
ENSG00000100121	0.056	0	0.225	0	0	0	1.11	0	3.28	0	0	0	GGTLC2	gamma-glutamyltransferase light chain 2 [Source:HGNC Symbol;Acc:HGNC:18596]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0036374//glutathione hydrolase activity	GO:0006508//proteolysis;GO:0006751//glutathione catabolic process;GO:0008150//biological_process;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000100122	0.926	0.645	0.502	1.125	0.439	0.064	20	14	8	18	8	1	CRYBB1	crystallin beta B1 [Source:HGNC Symbol;Acc:HGNC:2397]	-	-	-	-	-	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000100124	10.225	9.469	10.91	10.855	10.103	10.273	387	388	318	303	355	310	ANKRD54	ankyrin repeat domain 54 [Source:HGNC Symbol;Acc:HGNC:25185]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030496//midbody	GO:0005515//protein binding;GO:0019887//protein kinase regulator activity;GO:0044877//protein-containing complex binding	GO:0006913//nucleocytoplasmic transport;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045859//regulation of protein kinase activity;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000100129	205.726	192.647	195.281	203.569	180.656	173.153	7926	8044	5660	5675	6317	5148	EIF3L	eukaryotic translation initiation factor 3 subunit L [Source:HGNC Symbol;Acc:HGNC:18138]	-	-	-	-	GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0075525//viral translational termination-reinitiation	--
ENSG00000100138	58.256	63.072	70.34	70.927	75.358	79.865	1548	1677	1372	1380	1677	1541	SNU13	small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819]	Genetic Information Processing;Genetic Information Processing	Transcription;Translation	ko03040//Spliceosome;ko03008//Ribosome biogenesis in eukaryotes	K12845;K12845	GO:0001651//dense fibrillar component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005690//U4atac snRNP;GO:0005730//nucleolus;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome;GO:0032991//protein-containing complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0030621//U4 snRNA binding;GO:0030622//U4atac snRNA binding;GO:0034511//U3 snoRNA binding;GO:0034512//box C/D RNA binding;GO:0051117//ATPase binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0000470//maturation of LSU-rRNA;GO:0000492//box C/D snoRNP assembly;GO:0006397//mRNA processing;GO:0007338//single fertilization;GO:0008380//RNA splicing;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis"	--
ENSG00000100139	23.028	24.977	29.155	29.291	27.518	31.898	2042	2263	1899	1908	2186	2107	MICALL1	MICAL like 1 [Source:HGNC Symbol;Acc:HGNC:29804]	-	-	-	-	GO:0005768//endosome;GO:0005770//late endosome;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031902//late endosome membrane;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0070300//phosphatidic acid binding	GO:0006612//protein targeting to membrane;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0031175//neuron projection development;GO:0032456//endocytic recycling;GO:0032458//slow endocytic recycling;GO:0036010//protein localization to endosome;GO:0097320//plasma membrane tubulation	--
ENSG00000100142	35.805	37.917	35.349	42.412	34.449	42.876	535	561	403	477	428	456	POLR2F	"RNA polymerase II, I and III subunit F [Source:HGNC Symbol;Acc:HGNC:9193]"	Human Diseases;Organismal Systems;Genetic Information Processing	Neurodegenerative disease;Immune system;Transcription	ko05016//Huntington disease;ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03014;K03014;K03014	"GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000100146	51.345	57.574	64.686	68.197	65.44	66.468	2901	3259	2619	2888	3105	2707	SOX10	SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0031315//extrinsic component of mitochondrial outer membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001755//neural crest cell migration;GO:0002009//morphogenesis of an epithelium;GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007422//peripheral nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0010626//negative regulation of Schwann cell proliferation;GO:0010628//positive regulation of gene expression;GO:0014003//oligodendrocyte development;GO:0014015//positive regulation of gliogenesis;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0030318//melanocyte differentiation;GO:0031643//positive regulation of myelination;GO:0032808//lacrimal gland development;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048484//enteric nervous system development;GO:0048546//digestive tract morphogenesis;GO:0048589//developmental growth;GO:0048709//oligodendrocyte differentiation;GO:0048863//stem cell differentiation;GO:0061138//morphogenesis of a branching epithelium;GO:0071393//cellular response to progesterone stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway"	HMG
ENSG00000100147	2.041	1.862	1.949	1.697	2.095	2.108	302	277	213	186	262	227	CCDC134	coiled-coil domain containing 134 [Source:HGNC Symbol;Acc:HGNC:26185]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001890//placenta development;GO:0021591//ventricular system development;GO:0035162//embryonic hemopoiesis;GO:1990402//embryonic liver development	--
ENSG00000100150	2.472	4.248	3.149	2.048	2.594	3.076	271	309	227.73	155	236	230.31	DEPDC5	"DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20404	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm;GO:1990130//GATOR1 complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0010508//positive regulation of autophagy;GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000100151	15.25	16.35	17.409	18.26	19.655	18.7	468	510	411	400	452	401	PICK1	protein interacting with PRKCA 1 [Source:HGNC Symbol;Acc:HGNC:9394]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098842//postsynaptic early endosome	GO:0001664//G protein-coupled receptor binding;GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0071933//Arp2/3 complex binding;GO:0140090//membrane curvature sensor activity	"GO:0002092//positive regulation of receptor internalization;GO:0006468//protein phosphorylation;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0015844//monoamine transport;GO:0021782//glial cell development;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0036294//cellular response to decreased oxygen levels;GO:0042149//cellular response to glucose starvation;GO:0043045//DNA methylation involved in embryo development;GO:0043046//DNA methylation involved in gamete generation;GO:0043113//receptor clustering;GO:0045161//neuronal ion channel clustering;GO:0050796//regulation of insulin secretion;GO:0060292//long-term synaptic depression;GO:0097061//dendritic spine organization;GO:0097062//dendritic spine maintenance"	--
ENSG00000100154	8.405	7.698	8.374	7.301	8.26	8.306	1847	1789	1395	1258	1660	1418	TTC28	tetratricopeptide repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29179]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0019900//kinase binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0051301//cell division	--
ENSG00000100156	27.357	32.367	33.479	43.211	42.609	33.174	1300	1546	1175	1521	1708	1147	SLC16A8	solute carrier family 16 member 8 [Source:HGNC Symbol;Acc:HGNC:16270]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0015727//lactate transport;GO:0035873//lactate transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000100162	2.157	2.047	1.842	1.311	1.67	2.017	40	37	24	19	27	29	CENPM	centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol"	-	-	--
ENSG00000100167	30.613	31.58	25.005	16.12	18.054	17.025	2619	2650	1557	1030	1305	1041	SEPTIN3	septin 3 [Source:HGNC Symbol;Acc:HGNC:10750]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16938;K16938	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0031105//septin complex;GO:0032153//cell division site;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098793//presynapse;GO:0099569//presynaptic cytoskeleton	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000100170	0.051	0.03	0.055	0.137	0.108	0.123	5	3	4	10	9	9	SLC5A1	solute carrier family 5 member 1 [Source:HGNC Symbol;Acc:HGNC:11036]	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Digestive system	ko04976//Bile secretion;ko04978//Mineral absorption;ko04973//Carbohydrate digestion and absorption	K14158;K14158;K14158	GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097708//intracellular vesicle	GO:0005354//galactose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005367//myo-inositol:sodium symporter activity;GO:0005372//water transmembrane transporter activity;GO:0005412//glucose:sodium symporter activity;GO:0005515//protein binding;GO:0015146//pentose transmembrane transporter activity;GO:0015150//fucose transmembrane transporter activity;GO:0015151//alpha-glucoside transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0000017//alpha-glucoside transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008643//carbohydrate transport;GO:0010035//response to inorganic substance;GO:0015750//pentose transmembrane transport;GO:0015756//fucose transmembrane transport;GO:0015757//galactose transmembrane transport;GO:0015798//myo-inositol transport;GO:0035377//transepithelial water transport;GO:0055085//transmembrane transport;GO:0098708//glucose import across plasma membrane;GO:0098719//sodium ion import across plasma membrane;GO:0106001//intestinal hexose absorption;GO:0150104//transport across blood-brain barrier;GO:1904659//glucose transmembrane transport	--
ENSG00000100191	0	0	0	0	0	0	0	0	0	0	0	0	SLC5A4	solute carrier family 5 member 4 [Source:HGNC Symbol;Acc:HGNC:11039]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005412//glucose:sodium symporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000100196	8.361	8.845	6.859	5.806	3.977	4.576	286	293	178	139	114	117	KDELR3	KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306]	Human Diseases	Infectious disease: bacterial	ko05110//Vibrio cholerae infection	K10949	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005046//KDEL sequence binding;GO:0005515//protein binding;GO:0046923//ER retention sequence binding	"GO:0006621//protein retention in ER lumen;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport"	--
ENSG00000100197	0	0	0	0	0	0	0	0	0	0	0	0	CYP2D6	cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625]	Organismal Systems;Human Diseases;Metabolism;Metabolism	Nervous system;Drug resistance: antineoplastic;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism	ko04726//Serotonergic synapse;ko01522//Endocrine resistance;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00982//Drug metabolism - cytochrome P450	K17712;K17712;K17712;K17712	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0062187//anandamide 8,9 epoxidase activity;GO:0062188//anandamide 11,12 epoxidase activity;GO:0062189//anandamide 14,15 epoxidase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008210//estrogen metabolic process;GO:0009804//coumarin metabolic process;GO:0009820//alkaloid metabolic process;GO:0009822//alkaloid catabolic process;GO:0016098//monoterpenoid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0033076//isoquinoline alkaloid metabolic process;GO:0042178//xenobiotic catabolic process;GO:0042572//retinol metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0046483//heterocycle metabolic process;GO:0051100//negative regulation of binding;GO:0070989//oxidative demethylation;GO:0090350//negative regulation of cellular organofluorine metabolic process	--
ENSG00000100201	69.425	63.282	72.809	64.299	67.582	76.052	6438	6052	5187	4586	5426	5380	DDX17	DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:1990904//ribonucleoprotein complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008186//ATP-dependent activity, acting on RNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity"	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001837//epithelial to mesenchymal transition;GO:0002376//immune system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010586//miRNA metabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0031047//gene silencing by RNA;GO:0045445//myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:2001014//regulation of skeletal muscle cell differentiation"	--
ENSG00000100206	0.277	0.046	0	0.063	0.079	0.349	4	2	0	2	1	3	DMC1	DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005694//chromosome"	"GO:0000150//DNA strand exchange activity;GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0042802//identical protein binding"	GO:0000730//DNA recombinase assembly;GO:0001541//ovarian follicle development;GO:0001556//oocyte maturation;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006312//mitotic recombination;GO:0007049//cell cycle;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0007141//male meiosis I;GO:0007276//gamete generation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007292//female gamete generation;GO:0042148//strand invasion;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle	--
ENSG00000100207	6.253	8.365	6.444	5.806	7.527	6.477	784	913	615	502	669	570	TCF20	transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000100209	2.995	3.548	4.052	4.074	3.706	2.162	63	77.95	65.97	64.86	66.86	33	HSCB	HscB mitochondrial iron-sulfur cluster cochaperone [Source:HGNC Symbol;Acc:HGNC:28913]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0001671//ATPase activator activity;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0008152//metabolic process;GO:0016226//iron-sulfur cluster assembly;GO:0044571//[2Fe-2S] cluster assembly;GO:0051259//protein complex oligomerization	--
ENSG00000100211	22.16	19.255	18.851	18.532	17.063	16.7	535	468	337	331	349	297	CBY1	"chibby family member 1, beta catenin antagonist [Source:HGNC Symbol;Acc:HGNC:1307]"	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K23402	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	"GO:0008104//protein localization;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0033504//floor plate development;GO:0045444//fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051289//protein homotetramerization;GO:0055007//cardiac muscle cell differentiation;GO:0060271//cilium assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000100216	16.521	16.012	18.095	19.644	16.38	17.03	696	678	563	613	583	522	TOMM22	translocase of outer mitochondrial membrane 22 [Source:HGNC Symbol;Acc:HGNC:18002]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098588//bounding membrane of organelle	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0043065//positive regulation of apoptotic process;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0051204//protein insertion into mitochondrial membrane;GO:0071806//protein transmembrane transport	--
ENSG00000100218	0.586	0.166	0.275	0	0.284	0.554	10	2	5	0	5	9	RSPH14	radial spoke head 14 homolog [Source:HGNC Symbol;Acc:HGNC:13437]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000100219	66.87	67.534	67.991	68.108	71.566	58.29	2492	2529	1885	1885	2229	1593	XBP1	X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Folding, sorting and degradation;Endocrine and metabolic disease;Neurodegenerative disease"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05017//Spinocerebellar ataxia	K09027;K09027;K09027;K09027;K09027;K09027;K09027;K09027	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0002020//protease binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030331//estrogen receptor binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001558//regulation of cell growth;GO:0001889//liver development;GO:0001934//positive regulation of protein phosphorylation;GO:0001935//endothelial cell proliferation;GO:0002639//positive regulation of immunoglobulin production;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0006986//response to unfolded protein;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0006996//organelle organization;GO:0007517//muscle organ development;GO:0008284//positive regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0010832//negative regulation of myotube differentiation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031062//positive regulation of histone methylation;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0031670//cellular response to nutrient;GO:0032008//positive regulation of TOR signaling;GO:0032755//positive regulation of interleukin-6 production;GO:0032869//cellular response to insulin stimulus;GO:0034599//cellular response to oxidative stress;GO:0034976//response to endoplasmic reticulum stress;GO:0035356//cellular triglyceride homeostasis;GO:0035470//positive regulation of vascular wound healing;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036498//IRE1-mediated unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response;GO:0036503//ERAD pathway;GO:0042149//cellular response to glucose starvation;GO:0042307//positive regulation of protein import into nucleus;GO:0042632//cholesterol homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045579//positive regulation of B cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048666//neuron development;GO:0051897//positive regulation of protein kinase B signaling;GO:0055089//fatty acid homeostasis;GO:0055092//sterol homeostasis;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060612//adipose tissue development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071332//cellular response to fructose stimulus;GO:0071333//cellular response to glucose stimulus;GO:0071353//cellular response to interleukin-4;GO:0071375//cellular response to peptide hormone stimulus;GO:0071498//cellular response to fluid shear stress;GO:0071499//cellular response to laminar fluid shear stress;GO:1900100//positive regulation of plasma cell differentiation;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1901985//positive regulation of protein acetylation;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903489//positive regulation of lactation;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1990418//response to insulin-like growth factor stimulus;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000353//positive regulation of endothelial cell apoptotic process"	TF_bZIP
ENSG00000100220	40.045	40.624	39.541	44.068	41.265	42.04	1677	1710	1223	1367	1460	1281	RTCB	"RNA 2',3'-cyclic phosphate and 5'-OH ligase [Source:HGNC Symbol;Acc:HGNC:26935]"	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0072669//tRNA-splicing ligase complex	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003972//RNA ligase (ATP) activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008452//RNA ligase activity;GO:0016874//ligase activity;GO:0016886//ligase activity, forming phosphoric ester bonds;GO:0017166//vinculin binding;GO:0046872//metal ion binding"	"GO:0000971//tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate;GO:0001701//in utero embryonic development;GO:0001890//placenta development;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006396//RNA processing;GO:0008033//tRNA processing"	--
ENSG00000100221	17.501	16.715	14.884	15.496	15.179	16.245	1184	1223	815	844	952	889	JOSD1	Josephin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28953]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination	--
ENSG00000100225	76.217	78.422	85.521	76.436	73.503	83.662	3063	3190	2531	2276	2489	2449	FBXO7	F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0097409//glial cytoplasmic inclusion;GO:0097414//classical Lewy body;GO:0097462//Lewy neurite;GO:1990037//Lewy body core;GO:1990038//Lewy body corona	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0046982//protein heterodimerization activity;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0000422//autophagy of mitochondrion;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006626//protein targeting to mitochondrion;GO:0010975//regulation of neuron projection development;GO:0016567//protein ubiquitination;GO:0031647//regulation of protein stability;GO:0040012//regulation of locomotion;GO:0045620//negative regulation of lymphocyte differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:1901215//negative regulation of neuron death;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903208//negative regulation of hydrogen peroxide-induced neuron death;GO:1903599//positive regulation of autophagy of mitochondrion;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000100226	21.77	24.263	21.536	21.753	21.358	17.289	1773.5	1938.84	1402.99	1225.86	1462.91	1118.78	GTPBP1	GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4669]	-	-	-	-	GO:0000177//cytoplasmic exosome (RNase complex);GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006414//translational elongation;GO:0006955//immune response;GO:0007165//signal transduction;GO:0046039//GTP metabolic process;GO:0061014//positive regulation of mRNA catabolic process	--
ENSG00000100227	25.159	27.736	29.794	30.342	31.311	31.435	1755	1942.31	1536	1566	1747.01	1593	POLDIP3	DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0045727//positive regulation of translation;GO:0051028//mRNA transport	--
ENSG00000100228	3.488	4.639	4.212	3.659	3.751	3.718	338	458	309	277	328	280	RAB36	"RAB36, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9775]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0015031//protein transport	--
ENSG00000100234	1069.114	1176.812	1243.206	1320.809	1313.992	1225.048	101941	112787	87550	93288	105852	84991	TIMP3	TIMP metallopeptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:11822]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer	K16866;K16866	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0002020//protease binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0046872//metal ion binding	GO:0007601//visual perception;GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0034097//response to cytokine;GO:0050896//response to stimulus;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071310//cellular response to organic substance;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:1904684//negative regulation of metalloendopeptidase activity	--
ENSG00000100239	17.138	16.567	19.324	20.958	20.235	20.347	1111.26	1150.09	946.35	987.59	1081.38	1031.8	PPP6R2	protein phosphatase 6 regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:19253]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding	GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000100241	24.571	21.097	21.749	24.082	24.469	22.629	2899.74	2875.91	2222.65	2405.41	2830.62	2352.2	SBF1	SET binding factor 1 [Source:HGNC Symbol;Acc:HGNC:10542]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0019208//phosphatase regulator activity	GO:0006470//protein dephosphorylation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0043087//regulation of GTPase activity	--
ENSG00000100242	18.003	19.419	17.195	11.171	14.369	15.831	1261.5	1295.16	897.01	615.14	872.09	802.22	SUN2	Sad1 and UNC84 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:14210]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex"	GO:0005515//protein binding;GO:0005521//lamin binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0043495//protein-membrane adaptor activity;GO:0140444//cytoskeleton-nuclear membrane anchor activity	GO:0006998//nuclear envelope organization;GO:0007052//mitotic spindle organization;GO:0007097//nuclear migration;GO:0021817//nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration;GO:0030335//positive regulation of cell migration;GO:0031022//nuclear migration along microfilament;GO:0051321//meiotic cell cycle;GO:0051642//centrosome localization;GO:0090292//nuclear matrix anchoring at nuclear membrane	--
ENSG00000100243	97.042	108.747	101.289	117.278	117.845	115.936	3900.07	4417.59	3050.49	3505.75	4174.71	3375.86	CYB5R3	cytochrome b5 reductase 3 [Source:HGNC Symbol;Acc:HGNC:2873]	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005833//hemoglobin complex;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:1903958//nitric-oxide synthase complex	"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050421//nitrite reductase (NO-forming) activity;GO:0071949//FAD binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0008015//blood circulation;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process	--
ENSG00000100246	9.523	12.031	11.778	12.436	12.014	11.957	284	354	256	268	271	248	DNAL4	dynein axonemal light chain 4 [Source:HGNC Symbol;Acc:HGNC:2955]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10412;K10412;K10412	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0030286//dynein complex;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007017//microtubule-based process;GO:0007018//microtubule-based movement	--
ENSG00000100249	1.718	1.465	1.064	0.994	1.22	0.742	35	30	16	15	21	11	C22orf31	chromosome 22 open reading frame 31 [Source:HGNC Symbol;Acc:HGNC:26931]	-	-	-	-	-	-	-	--
ENSG00000100253	0	0	0	0	0	0	0	0	0	0	0	0	MIOX	myo-inositol oxygenase [Source:HGNC Symbol;Acc:HGNC:14522]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism;ko00053//Ascorbate and aldarate metabolism	K00469;K00469;K00469	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016234//inclusion body	"GO:0004033//aldo-keto reductase (NADP) activity;GO:0005506//iron ion binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0050113//inositol oxygenase activity"	GO:0019310//inositol catabolic process	--
ENSG00000100258	32.056	33.384	34.98	36.789	39.87	33.59	1725	1805	1391	1467	1812	1315	LMF2	lipase maturation factor 2 [Source:HGNC Symbol;Acc:HGNC:25096]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0051604//protein maturation	--
ENSG00000100263	14.701	13.939	17.184	16.278	16.479	14.602	485	477	396	405	476	344	RHBDD3	rhomboid domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1308]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding	GO:0000165//MAPK cascade;GO:0001889//liver development;GO:0002673//regulation of acute inflammatory response;GO:0006508//proteolysis;GO:0009410//response to xenobiotic stimulus;GO:0032815//negative regulation of natural killer cell activation;GO:0045732//positive regulation of protein catabolic process;GO:0050708//regulation of protein secretion	--
ENSG00000100266	22.1	19.106	21.186	20.158	19.719	22.059	1304	1232	969	963	1028	1000	PACSIN2	protein kinase C and casein kinase substrate in neurons 2 [Source:HGNC Symbol;Acc:HGNC:8571]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0019898//extrinsic component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0070300//phosphatidic acid binding	GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0030100//regulation of endocytosis;GO:0036010//protein localization to endosome;GO:0045806//negative regulation of endocytosis;GO:0048858//cell projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0070836//caveola assembly;GO:0072584//caveolin-mediated endocytosis;GO:0097320//plasma membrane tubulation	--
ENSG00000100271	5.451	5.652	5.117	5.003	5.961	3.53	194	204	135	133	181	92	TTLL1	tubulin tyrosine ligase like 1 [Source:HGNC Symbol;Acc:HGNC:1312]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0002395//immune response in nasopharyngeal-associated lymphoid tissue;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0006464//cellular protein modification process;GO:0007288//sperm axoneme assembly;GO:0018095//protein polyglutamylation;GO:0021702//cerebellar Purkinje cell differentiation;GO:0030317//flagellated sperm motility;GO:0035082//axoneme assembly;GO:0120197//mucociliary clearance;GO:0120222//regulation of blastocyst development	--
ENSG00000100276	0	0	0	0	0	0	0	0	0	0	0	0	RASL10A	RAS like family 10 member A [Source:HGNC Symbol;Acc:HGNC:16954]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0007264//small GTPase mediated signal transduction	--
ENSG00000100280	30.895	30.346	32.709	32.739	36.018	29.247	2586	2623	2002	2084	2523	1785	AP1B1	adaptor related protein complex 1 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:554]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12392;K12392	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030121//AP-1 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097708//intracellular vesicle	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030276//clathrin binding	GO:0001822//kidney development;GO:0006886//intracellular protein transport;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060155//platelet dense granule organization;GO:0110010//basolateral protein secretion;GO:1903232//melanosome assembly	--
ENSG00000100281	4.748	4.384	3.62	2.733	4.891	4.172	311	290	185	173	266	184	HMGXB4	HMG-box containing 4 [Source:HGNC Symbol;Acc:HGNC:5003]	-	-	-	-	GO:0005634//nucleus;GO:0016589//NURF complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008333//endosome to lysosome transport;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway	HMG
ENSG00000100284	34.095	38.499	38.712	35.32	33.435	33.653	1492	1717	1130	1171	1284	1022	TOM1	target of myb1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11982]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030276//clathrin binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016197//endosomal transport	--
ENSG00000100285	1.22	0.961	0.808	0.686	1.053	0.786	96	76	47	40	70	45	NEFH	neurofilament heavy chain [Source:HGNC Symbol;Acc:HGNC:7737]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K04574;K04574	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005883//neurofilament;GO:0014069//postsynaptic density;GO:0030424//axon;GO:0042995//cell projection;GO:0097418//neurofibrillary tangle;GO:0098685//Schaffer collateral - CA1 synapse;GO:0099160//postsynaptic intermediate filament cytoskeleton	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0070840//dynein complex binding;GO:0099184//structural constituent of postsynaptic intermediate filament cytoskeleton	GO:0000226//microtubule cytoskeleton organization;GO:0007409//axonogenesis;GO:0030031//cell projection assembly;GO:0033693//neurofilament bundle assembly;GO:0045104//intermediate filament cytoskeleton organization;GO:0045110//intermediate filament bundle assembly;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0060052//neurofilament cytoskeleton organization;GO:0061564//axon development;GO:0099185//postsynaptic intermediate filament cytoskeleton organization;GO:1902513//regulation of organelle transport along microtubule;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000100288	7.347	7.923	9.164	9.222	7.958	9.3	224.64	243.49	206.93	208.85	205.57	206.88	CHKB	choline kinase beta [Source:HGNC Symbol;Acc:HGNC:1938]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism	K14156;K14156;K14156	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004103//choline kinase activity;GO:0004305//ethanolamine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0007517//muscle organ development;GO:0008654//phospholipid biosynthetic process;GO:0016310//phosphorylation;GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000100290	0.355	0.151	0.069	0.137	0.3	0.488	7	3	1	2	5	7	BIK	BCL2 interacting killer [Source:HGNC Symbol;Acc:HGNC:1051]	Human Diseases	Drug resistance: antineoplastic	ko01522//Endocrine resistance	K18452	GO:0005739//mitochondrion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0097136//Bcl-2 family protein complex	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0008584//male gonad development;GO:0008637//apoptotic mitochondrial changes;GO:0031334//positive regulation of protein-containing complex assembly;GO:0042981//regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria	--
ENSG00000100292	113.226	121.843	59.124	57.818	76.681	38.043	3635	3937	1381	1367	2073	876	HMOX1	heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:5013]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Metabolism;Cellular Processes	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Signal transduction;Digestive system;Metabolism of cofactors and vitamins;Cell growth and death	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko04066//HIF-1 signaling pathway;ko04978//Mineral absorption;ko00860//Porphyrin metabolism;ko04216//Ferroptosis	K00510;K00510;K00510;K00510;K00510;K00510;K00510;K00510;K00510;K00510	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0004392//heme oxygenase (decyclizing) activity;GO:0004630//phospholipase D activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001935//endothelial cell proliferation;GO:0002246//wound healing involved in inflammatory response;GO:0002686//negative regulation of leukocyte migration;GO:0006788//heme oxidation;GO:0006879//cellular iron ion homeostasis;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0007264//small GTPase mediated signal transduction;GO:0008217//regulation of blood pressure;GO:0008219//cell death;GO:0008285//negative regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009410//response to xenobiotic stimulus;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0014806//smooth muscle hyperplasia;GO:0016239//positive regulation of macroautophagy;GO:0016242//negative regulation of macroautophagy;GO:0031670//cellular response to nutrient;GO:0032722//positive regulation of chemokine production;GO:0032764//negative regulation of mast cell cytokine production;GO:0034101//erythrocyte homeostasis;GO:0034383//low-density lipoprotein particle clearance;GO:0034395//regulation of transcription from RNA polymerase II promoter in response to iron;GO:0034605//cellular response to heat;GO:0035094//response to nicotine;GO:0035556//intracellular signal transduction;GO:0042167//heme catabolic process;GO:0042168//heme metabolic process;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043305//negative regulation of mast cell degranulation;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0043627//response to estrogen;GO:0045765//regulation of angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0055072//iron ion homeostasis;GO:0071243//cellular response to arsenic-containing substance;GO:0071276//cellular response to cadmium ion;GO:0071456//cellular response to hypoxia;GO:0072719//cellular response to cisplatin;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0097421//liver regeneration;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation	--
ENSG00000100294	7.298	8.033	7.235	6.743	8.111	6.516	235	256	183	157	217	157	MCAT	malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis	K00645;K00645;K00645	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0004312//fatty acid synthase activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0016419//S-malonyltransferase activity;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000100296	10.591	11.092	9.715	7.361	9.587	8.979	520	562	379	301	432	348	THOC5	THO complex 5 [Source:HGNC Symbol;Acc:HGNC:19074]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K13174	"GO:0000346//transcription export complex;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm"	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0030224//monocyte differentiation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0046784//viral mRNA export from host cell nucleus;GO:0051028//mRNA transport;GO:0060215//primitive hemopoiesis;GO:2000002//negative regulation of DNA damage checkpoint"	--
ENSG00000100297	6.796	6.854	6.023	7.466	5.429	4.562	369	434	278	239	288	186	MCM5	minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02209;K02209	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0042555//MCM complex;GO:0043229//intracellular organelle;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0043138//3'-5' DNA helicase activity	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:0051301//cell division;GO:0071704//organic substance metabolic process	--
ENSG00000100298	0	0	0	0	0	0	0	0	0	0	0	0	APOBEC3H	apolipoprotein B mRNA editing enzyme catalytic subunit 3H [Source:HGNC Symbol;Acc:HGNC:24100]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016554//cytidine to uridine editing;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0048525//negative regulation of viral process;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000100299	35.799	37.85	36.887	39.46	37.03	34.2	1624	1748	1243	1329	1411	1165	ARSA	arylsulfatase A [Source:HGNC Symbol;Acc:HGNC:713]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00600//Sphingolipid metabolism	K01134;K01134;K01134	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031232//extrinsic component of external side of plasma membrane;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0004098//cerebroside-sulfatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006914//autophagy;GO:0007339//binding of sperm to zona pellucida;GO:0007417//central nervous system development;GO:0007584//response to nutrient;GO:0009268//response to pH;GO:0043627//response to estrogen;GO:0045471//response to ethanol;GO:0051597//response to methylmercury	--
ENSG00000100300	84.947	90.662	88.296	101.635	94.081	107.903	1461	1576	1126	1294	1372	1354	TSPO	translocator protein [Source:HGNC Symbol;Acc:HGNC:1158]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04979//Cholesterol metabolism	K05770;K05770;K05770	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005497//androgen binding;GO:0005515//protein binding;GO:0008503//benzodiazepine receptor activity;GO:0015485//cholesterol binding;GO:0044325//transmembrane transporter binding;GO:0120020//cholesterol transfer activity	GO:0006626//protein targeting to mitochondrion;GO:0006694//steroid biosynthetic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0006783//heme biosynthetic process;GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0006869//lipid transport;GO:0007568//aging;GO:0008202//steroid metabolic process;GO:0008347//glial cell migration;GO:0009410//response to xenobiotic stimulus;GO:0010042//response to manganese ion;GO:0010266//response to vitamin B1;GO:0010823//negative regulation of mitochondrion organization;GO:0010940//positive regulation of necrotic cell death;GO:0014012//peripheral nervous system axon regeneration;GO:0015918//sterol transport;GO:0030325//adrenal gland development;GO:0031397//negative regulation of protein ubiquitination;GO:0032374//regulation of cholesterol transport;GO:0032570//response to progesterone;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033574//response to testosterone;GO:0042127//regulation of cell population proliferation;GO:0042632//cholesterol homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0048265//response to pain;GO:0048266//behavioral response to pain;GO:0048678//response to axon injury;GO:0050810//regulation of steroid biosynthetic process;GO:0051901//positive regulation of mitochondrial depolarization;GO:0051928//positive regulation of calcium ion transport;GO:0060242//contact inhibition;GO:0060252//positive regulation of glial cell proliferation;GO:0060253//negative regulation of glial cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0071294//cellular response to zinc ion;GO:0071476//cellular hypotonic response;GO:0072655//establishment of protein localization to mitochondrion;GO:0072656//maintenance of protein location in mitochondrion;GO:0120009//intermembrane lipid transfer;GO:1903147//negative regulation of autophagy of mitochondrion;GO:1903579//negative regulation of ATP metabolic process;GO:1905144//response to acetylcholine;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000853//negative regulation of corticosterone secretion	--
ENSG00000100302	0.168	0.153	0.17	0.227	0.232	0.365	12	11	9	12	14	19	RASD2	RASD family member 2 [Source:HGNC Symbol;Acc:HGNC:18229]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0031681//G-protein beta-subunit binding	"GO:0001963//synaptic transmission, dopaminergic;GO:0007626//locomotory behavior;GO:0033235//positive regulation of protein sumoylation;GO:0043949//regulation of cAMP-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling"	--
ENSG00000100304	21.002	25.364	22.556	30.872	26.763	28.862	1475	1571	1170	1452	1588	1391	TTLL12	tubulin tyrosine ligase like 12 [Source:HGNC Symbol;Acc:HGNC:28974]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:1990889//H4K20me3 modified histone binding	GO:0002376//immune system process;GO:0006464//cellular protein modification process;GO:0007346//regulation of mitotic cell cycle;GO:0045087//innate immune response;GO:0060339//negative regulation of type I interferon-mediated signaling pathway	--
ENSG00000100307	3.996	3.089	4.833	5.35	5.716	4.642	294	231	254	323	384	288	CBX7	chromobox 7 [Source:HGNC Symbol;Acc:HGNC:1557]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003006//developmental process involved in reproduction;GO:0006325//chromatin organization;GO:0009410//response to xenobiotic stimulus;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter	--
ENSG00000100311	0.155	0.666	0.158	0.214	0.122	0.394	12	28	9	8	8	9	PDGFB	platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Infectious disease: viral;Cancer: overview;Signal transduction;Cardiovascular disease;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05211//Renal cell carcinoma;ko05218//Melanoma	K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386;K17386	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1990265//platelet-derived growth factor complex	GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008083//growth factor activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0048018//receptor ligand activity;GO:0048407//platelet-derived growth factor binding;GO:0070851//growth factor receptor binding	"GO:0001892//embryonic placenta development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002548//monocyte chemotaxis;GO:0003104//positive regulation of glomerular filtration;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0009611//response to wounding;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:0010544//negative regulation of platelet activation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010811//positive regulation of cell-substrate adhesion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014911//positive regulation of smooth muscle cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032091//negative regulation of protein binding;GO:0032147//activation of protein kinase activity;GO:0032148//activation of protein kinase B activity;GO:0035655//interleukin-18-mediated signaling pathway;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038001//paracrine signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0050921//positive regulation of chemotaxis;GO:0051781//positive regulation of cell division;GO:0060326//cell chemotaxis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070528//protein kinase C signaling;GO:0071363//cellular response to growth factor stimulus;GO:0071506//cellular response to mycophenolic acid;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0072255//metanephric glomerular mesangial cell development;GO:0072593//reactive oxygen species metabolic process;GO:0090280//positive regulation of calcium ion import;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1905064//negative regulation of vascular associated smooth muscle cell differentiation;GO:1905176//positive regulation of vascular associated smooth muscle cell dedifferentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:2000591//positive regulation of metanephric mesenchymal cell migration"	--
ENSG00000100312	0.034	0	0	0	0	0	1	0	0	0	0	0	ACR	acrosin [Source:HGNC Symbol;Acc:HGNC:126]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005798//Golgi-associated vesicle;GO:0032991//protein-containing complex;GO:0043159//acrosomal matrix	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0004040//amidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042806//fucose binding	GO:0002077//acrosome matrix dispersal;GO:0006508//proteolysis;GO:0007190//activation of adenylate cyclase activity;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0007340//acrosome reaction;GO:0007341//penetration of zona pellucida;GO:0030163//protein catabolic process;GO:0048545//response to steroid hormone	--
ENSG00000100314	0.074	0.117	0.142	0.06	0.07	0.164	5.15	8.16	7.23	3.08	4.09	8.27	CABP7	calcium binding protein 7 [Source:HGNC Symbol;Acc:HGNC:20834]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000100316	1069.481	1110.059	1091.87	1181.859	1062.042	985.287	28721	29979	21652	23520	24105	19247	RPL3	ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02925;K02925	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000100319	10.757	10.397	10.76	12.185	11.106	12.181	210.85	204.84	155.77	176.92	183.91	173.73	ZMAT5	zinc finger matrin-type 5 [Source:HGNC Symbol;Acc:HGNC:28046]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:1990904//ribonucleoprotein complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000100320	22.798	21.826	18.596	16.103	18.435	18.806	2269	2119	1489	1244	1632	1473	RBFOX2	RNA binding fox-1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:9906]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0016070//RNA metabolic process;GO:0021942//radial glia guided migration of Purkinje cell;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043484//regulation of RNA splicing;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048813//dendrite morphogenesis;GO:0050885//neuromuscular process controlling balance"	--
ENSG00000100321	22.531	24.224	25.025	34.47	26.415	29.43	877	897	808	929	959	999	SYNGR1	synaptogyrin 1 [Source:HGNC Symbol;Acc:HGNC:11498]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0035577//azurophil granule membrane;GO:0042470//melanosome;GO:0045202//synapse	GO:0005515//protein binding	GO:0006605//protein targeting;GO:0045055//regulated exocytosis;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048499//synaptic vesicle membrane organization;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000100324	11.511	12.718	15.513	14.002	14.694	14.006	736	841	760	688	806	676	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18157]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Development and regeneration;Signal transduction;Infectious disease: parasitic;Immune system	ko05168//Herpes simplex virus 1 infection;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05161//Hepatitis B;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04620//Toll-like receptor signaling pathway	K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403;K04403	GO:0005634//nucleus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016301//kinase activity;GO:0016791//phosphatase activity;GO:0019209//kinase activator activity;GO:0044877//protein-containing complex binding;GO:0048273//mitogen-activated protein kinase p38 binding	GO:0001701//in utero embryonic development;GO:0003007//heart morphogenesis;GO:0003279//cardiac septum development;GO:0006470//protein dephosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016310//phosphorylation;GO:0016311//dephosphorylation;GO:0030324//lung development;GO:0035904//aorta development;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0060976//coronary vasculature development;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000100325	18.18	21.347	21.232	19.028	18.752	17.116	1024	1221	817	792	910	706	ASCC2	activating signal cointegrator 1 complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24103]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0099053//activating signal cointegrator 1 complex	GO:0005515//protein binding;GO:0043130//ubiquitin binding	"GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0072344//rescue of stalled ribosome;GO:1990116//ribosome-associated ubiquitin-dependent protein catabolic process"	--
ENSG00000100330	10.964	11.344	13.7	9.588	10.063	11.299	1450	1529	1159	958	1166	1105	MTMR3	myotubularin related protein 3 [Source:HGNC Symbol;Acc:HGNC:7451]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04140//Autophagy - animal;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18082;K18082;K18082;K18082	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019903//protein phosphatase binding;GO:0046872//metal ion binding;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0010506//regulation of autophagy;GO:0016236//macroautophagy;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042149//cellular response to glucose starvation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0060304//regulation of phosphatidylinositol dephosphorylation;GO:1904562//phosphatidylinositol 5-phosphate metabolic process;GO:2000785//regulation of autophagosome assembly	--
ENSG00000100335	14.329	14.917	17.51	16.916	15.611	16.436	1436	1446.56	1228.7	1160	1278	1186	MIEF1	mitochondrial elongation factor 1 [Source:HGNC Symbol;Acc:HGNC:25979]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0019003//GDP binding;GO:0042802//identical protein binding;GO:0043531//ADP binding	GO:0000266//mitochondrial fission;GO:0007005//mitochondrion organization;GO:0071456//cellular response to hypoxia;GO:0090141//positive regulation of mitochondrial fission;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000100336	2.814	3.012	3.017	1.693	1.407	1.496	144	178	124	64	80	72	APOL4	apolipoprotein L4 [Source:HGNC Symbol;Acc:HGNC:14867]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process	--
ENSG00000100341	0.095	0.069	0.108	0.13	0.029	0.13	5	3	2	4	1	5	PNPLA5	patatin like phospholipase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:24888]	-	-	-	-	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane	GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0055088//lipid homeostasis	--
ENSG00000100342	0.803	1.197	1.799	1.663	1.569	2.251	41	61.06	61	64	58	62	APOL1	apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618]	Human Diseases	Infectious disease: parasitic	ko05143//African trypanosomiasis	K23585	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031224//intrinsic component of membrane;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0072562//blood microparticle	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0042157//lipoprotein metabolic process;GO:0045087//innate immune response;GO:0051838//cytolysis by host of symbiont cells;GO:1902476//chloride transmembrane transport	--
ENSG00000100344	25.415	25.985	25.856	24.158	27.591	31.861	1283	1302	962	924	1203	1122	PNPLA3	patatin like phospholipase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18590]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism	K13534;K13534	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004465//lipoprotein lipase activity;GO:0004623//phospholipase A2 activity;GO:0004806//triglyceride lipase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0035727//lysophosphatidic acid binding;GO:0036042//long-chain fatty acyl-CoA binding;GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0051264//mono-olein transacylation activity;GO:0051265//diolein transacylation activity	"GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0009744//response to sucrose;GO:0016042//lipid catabolic process;GO:0019432//triglyceride biosynthetic process;GO:0019433//triglyceride catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0034389//lipid droplet organization;GO:0036153//triglyceride acyl-chain remodeling;GO:0036155//acylglycerol acyl-chain remodeling;GO:0050872//white fat cell differentiation;GO:0055088//lipid homeostasis;GO:1905243//cellular response to 3,3',5-triiodo-L-thyronine"	--
ENSG00000100345	152	157.716	146.488	122.68	133.755	107.121	23456	24456	16672	14031	17448	12034	MYH9	myosin heavy chain 9 [Source:HGNC Symbol;Acc:HGNC:7579]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Circulatory system	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04530//Tight junction;ko04270//Vascular smooth muscle contraction	K10352;K10352;K10352;K10352	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0001772//immunological synapse;GO:0001931//uropod;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005826//actomyosin contractile ring;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0008180//COP9 signalosome;GO:0009898//cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0016604//nuclear body;GO:0030863//cortical cytoskeleton;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex;GO:0042641//actomyosin;GO:0060473//cortical granule;GO:0070062//extracellular exosome;GO:0097513//myosin II filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043495//protein-membrane adaptor activity;GO:0043531//ADP binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	"GO:0000212//meiotic spindle organization;GO:0000904//cell morphogenesis involved in differentiation;GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001768//establishment of T cell polarity;GO:0001778//plasma membrane repair;GO:0006509//membrane protein ectodomain proteolysis;GO:0006911//phagocytosis, engulfment;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007520//myoblast fusion;GO:0008360//regulation of cell shape;GO:0015031//protein transport;GO:0030048//actin filament-based movement;GO:0030220//platelet formation;GO:0030224//monocyte differentiation;GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization;GO:0032418//lysosome localization;GO:0032506//cytokinetic process;GO:0032796//uropod organization;GO:0043534//blood vessel endothelial cell migration;GO:0045055//regulated exocytosis;GO:0050900//leukocyte migration;GO:0051295//establishment of meiotic spindle localization;GO:0060471//cortical granule exocytosis;GO:0070527//platelet aggregation;GO:0098609//cell-cell adhesion;GO:1903919//negative regulation of actin filament severing;GO:1903923//positive regulation of protein processing in phagocytic vesicle;GO:1905684//regulation of plasma membrane repair"	--
ENSG00000100346	0.005	0.016	0.044	0.067	0.081	0.027	1	3	4	9	14	4	CACNA1I	calcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04934//Cushing syndrome;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion	K04856;K04856;K04856;K04856;K04856;K04856;K04856	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008332//low voltage-gated calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0019228//neuronal action potential;GO:0030317//flagellated sperm motility;GO:0030431//sleep;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0086010//membrane depolarization during action potential	--
ENSG00000100347	28.18	28.32	29.591	29.927	27.251	29.136	989	999	767	778	808	744	SAMM50	SAMM50 sorting and assembly machinery component [Source:HGNC Symbol;Acc:HGNC:24276]	-	-	-	-	GO:0001401//SAM complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019867//outer membrane;GO:0070062//extracellular exosome;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0034622//cellular protein-containing complex assembly;GO:0042407//cristae formation;GO:0045040//protein insertion into mitochondrial outer membrane	--
ENSG00000100348	50.284	53.139	60.371	71.145	58.775	60.462	1375	1460	1215	1442	1359	1196	TXN2	thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial;Immune system;Cardiovascular disease	ko05012//Parkinson disease;ko05132//Salmonella infection;ko04621//NOD-like receptor signaling pathway;ko05418//Fluid shear stress and atherosclerosis	K03671;K03671;K03671;K03671	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0005515//protein binding;GO:0008113//peptide-methionine (S)-S-oxide reductase activity;GO:0015035//protein-disulfide reductase activity;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0044877//protein-containing complex binding	GO:0001666//response to hypoxia;GO:0006979//response to oxidative stress;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0009749//response to glucose;GO:0014070//response to organic cyclic compound;GO:0031669//cellular response to nutrient levels;GO:0045454//cell redox homeostasis;GO:0048678//response to axon injury	--
ENSG00000100350	22.329	24.522	25.089	28.987	28.11	29.109	2062	2240	1764	1944	2122	1732	FOXRED2	FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000100351	0	0	0.017	0.017	0	0	0	0	1	1	0	0	GRAP2	GRB2 related adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:4563]	Organismal Systems	Immune system	ko04660//T cell receptor signaling pathway	K07366	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0007265//Ras protein signal transduction;GO:0007267//cell-cell signaling	--
ENSG00000100353	76.127	79.398	76.657	82.953	77.051	77.169	2944	3105	2193	2392	2508	2177	EIF3D	eukaryotic translation initiation factor 3 subunit D [Source:HGNC Symbol;Acc:HGNC:3278]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0098808//mRNA cap binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0002191//cap-dependent translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0045727//positive regulation of translation;GO:0075522//IRES-dependent viral translational initiation;GO:0075525//viral translational termination-reinitiation;GO:1902416//positive regulation of mRNA binding	--
ENSG00000100354	2.295	2.182	1.73	1.394	1.795	1.926	665	505	391	290	435	335	TNRC6B	trinucleotide repeat containing adaptor 6B [Source:HGNC Symbol;Acc:HGNC:29190]	-	-	-	-	GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006417//regulation of translation;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1905618//positive regulation of miRNA mediated inhibition of translation"	--
ENSG00000100359	13.654	14.158	15.952	16.761	14.694	17.223	700.83	718.32	582.32	633.19	633.1	618.86	SGSM3	small G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:25228]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005921//gap junction	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007049//cell cycle;GO:0032483//regulation of Rab protein signal transduction;GO:0032486//Rap protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0045732//positive regulation of protein catabolic process;GO:0048227//plasma membrane to endosome transport;GO:0090630//activation of GTPase activity	--
ENSG00000100360	9.667	12.665	12.399	11.95	9.805	11.563	213	270	198	197	182	183	IFT27	intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0001822//kidney development;GO:0006886//intracellular protein transport;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060271//cilium assembly;GO:0090102//cochlea development	--
ENSG00000100362	0.438	1.444	0.356	2.3	2.075	0.723	5	16	3	18	20	6	PVALB	parvalbumin [Source:HGNC Symbol;Acc:HGNC:9704]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon;GO:0032420//stereocilium;GO:0032437//cuticular plate;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0010467//gene expression;GO:0090102//cochlea development;GO:0098976//excitatory chemical synaptic transmission;GO:0098977//inhibitory chemical synaptic transmission	--
ENSG00000100364	13.172	14.116	13.207	15.356	12.894	11.376	848	938	646	763	773	595	KIAA0930	KIAA0930 [Source:HGNC Symbol;Acc:HGNC:1314]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000100365	0	0	0	0	0.045	0	0	0	0	0	1	0	NCF4	neutrophil cytosolic factor 4 [Source:HGNC Symbol;Acc:HGNC:7662]	Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Immune system;Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Infectious disease: parasitic;Development and regeneration;Immune system	ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko04670//Leukocyte transendothelial migration	K08012;K08012;K08012;K08012;K08012;K08012;K08012;K08012	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0032010//phagolysosome;GO:0043020//NADPH oxidase complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding	GO:0006909//phagocytosis;GO:0042554//superoxide anion generation;GO:0045730//respiratory burst;GO:0050790//regulation of catalytic activity	--
ENSG00000100368	0	0	0	0	0.035	0	0	0	0	0	3	0	CSF2RB	colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cell growth and death	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04210//Apoptosis	K04738;K04738;K04738;K04738	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030526//granulocyte macrophage colony-stimulating factor receptor complex	GO:0004896//cytokine receptor activity;GO:0004912//interleukin-3 receptor activity;GO:0004914//interleukin-5 receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0036016//cellular response to interleukin-3;GO:0038043//interleukin-5-mediated signaling pathway;GO:0038156//interleukin-3-mediated signaling pathway;GO:0038157//granulocyte-macrophage colony-stimulating factor signaling pathway;GO:0070665//positive regulation of leukocyte proliferation	--
ENSG00000100372	14.291	16.483	16.308	12.325	13.025	13.482	568	619	433	374	433	389	SLC25A17	solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13354	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000295//adenine nucleotide transmembrane transporter activity;GO:0005347//ATP transmembrane transporter activity;GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding;GO:0015217//ADP transmembrane transporter activity;GO:0015228//coenzyme A transmembrane transporter activity;GO:0015230//FAD transmembrane transporter activity;GO:0044610//FMN transmembrane transporter activity;GO:0051087//chaperone binding;GO:0051724//NAD transmembrane transporter activity;GO:0080122//AMP transmembrane transporter activity	GO:0001561//fatty acid alpha-oxidation;GO:0006635//fatty acid beta-oxidation;GO:0015866//ADP transport;GO:0015867//ATP transport;GO:0015908//fatty acid transport;GO:0035349//coenzyme A transmembrane transport;GO:0035350//FAD transmembrane transport;GO:0035352//NAD transmembrane transport;GO:0055085//transmembrane transport;GO:0080121//AMP transport;GO:0140021//mitochondrial ADP transmembrane transport;GO:1901679//nucleotide transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport	--
ENSG00000100373	1.069	1.729	1.064	0.6	1.535	0.795	23	37	14	10	23	12	UPK3A	uroplakin 3A [Source:HGNC Symbol;Acc:HGNC:12580]	Human Diseases	Cancer: specific types	ko05219//Bladder cancer	K19520	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0120001//apical plasma membrane urothelial plaque	GO:0005515//protein binding	GO:0000902//cell morphogenesis;GO:0001822//kidney development;GO:0006833//water transport;GO:0015840//urea transport;GO:0030855//epithelial cell differentiation;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0060157//urinary bladder development	--
ENSG00000100376	2.623	2.401	3.256	2.761	2.534	3.386	154	142	137	96	128	145	FAM118A	family with sequence similarity 118 member A [Source:HGNC Symbol;Acc:HGNC:1313]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000100379	4.792	5.159	6.454	5.256	6.75	4.231	160	178	160	129	187	103	KCTD17	potassium channel tetramerization domain containing 17 [Source:HGNC Symbol;Acc:HGNC:25705]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0097602//cullin family protein binding	GO:0030030//cell projection organization;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045724//positive regulation of cilium assembly;GO:0051260//protein homooligomerization	--
ENSG00000100380	184.372	186.688	172.081	164.35	147.865	153.279	9155	8774	6197	5588	6391	5515	ST13	ST13 Hsp70 interacting protein [Source:HGNC Symbol;Acc:HGNC:11343]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031072//heat shock protein binding;GO:0046983//protein dimerization activity	GO:0006457//protein folding;GO:0009617//response to bacterium;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0065003//protein-containing complex assembly	--
ENSG00000100385	0	0.012	0	0	0.201	0	0	1	0	0	2	0	IL2RB	interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Signaling molecules and interaction;Cancer: overview;Transport and catabolism;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Signaling molecules and interaction;Immune system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04658//Th1 and Th2 cell differentiation	K05069;K05069;K05069;K05069;K05069;K05069;K05069;K05069;K05069;K05069;K05069	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005893//interleukin-2 receptor complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004911//interleukin-2 receptor activity;GO:0005515//protein binding;GO:0019976//interleukin-2 binding;GO:0042010//interleukin-15 receptor activity	GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030101//natural killer cell activation;GO:0035723//interleukin-15-mediated signaling pathway;GO:0038110//interleukin-2-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050766//positive regulation of phagocytosis;GO:0065003//protein-containing complex assembly	--
ENSG00000100387	20.167	19.777	20.884	23.384	21.088	24.486	489	482	374	420	432	432	RBX1	ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Genetic Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing;Organismal Systems	"Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Folding, sorting and degradation;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Signal transduction;Signal transduction;Cancer: specific types;Replication and repair;Environmental adaptation"	ko05200//Pathways in cancer;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04066//HIF-1 signaling pathway;ko04350//TGF-beta signaling pathway;ko05211//Renal cell carcinoma;ko03420//Nucleotide excision repair;ko04710//Circadian rhythm	K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868;K03868	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019788//NEDD8 transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061630//ubiquitin protein ligase activity;GO:0061663//NEDD8 ligase activity;GO:0097602//cullin family protein binding	GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0000302//response to reactive oxygen species;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034644//cellular response to UV;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation;GO:0070936//protein K48-linked ubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1902499//positive regulation of protein autoubiquitination	--
ENSG00000100393	15.656	13.85	14.78	11.753	14.413	14.372	2670	2519	1981	1581	2202	1894	EP300	E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Signal transduction;Cell growth and death;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Endocrine system;Cancer: specific types;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Nervous system;Signal transduction	"ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko05161//Hepatitis B;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04350//TGF-beta signaling pathway;ko05211//Renal cell carcinoma;ko04520//Adherens junction;ko04720//Long-term potentiation;ko04330//Notch signaling pathway"	K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498;K04498	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	"GO:0001221//transcription coregulator binding;GO:0001223//transcription coactivator binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0010484//H3 histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016922//nuclear receptor binding;GO:0031490//chromatin DNA binding;GO:0034212//peptide N-acetyltransferase activity;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050681//androgen receptor binding;GO:0051059//NF-kappaB binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061733//peptide-lysine-N-acetyltransferase activity;GO:0061920//protein propionyltransferase activity;GO:0097157//pre-mRNA intronic binding;GO:0097677//STAT family protein binding;GO:0106226//peptide 2-hydroxyisobutyryltransferase activity;GO:0120300//peptide lactyltransferase activity;GO:0120301//histone lactyltransferase activity;GO:0140065//peptide butyryltransferase activity;GO:0140068//histone crotonyltransferase activity;GO:0140069//histone butyryltransferase activity;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0001756//somitogenesis;GO:0001966//thigmotaxis;GO:0002209//behavioral defense response;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006110//regulation of glycolytic process;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006473//protein acetylation;GO:0006475//internal protein amino acid acetylation;GO:0006915//apoptotic process;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0007611//learning or memory;GO:0007623//circadian rhythm;GO:0009887//animal organ morphogenesis;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010742//macrophage derived foam cell differentiation;GO:0010821//regulation of mitochondrion organization;GO:0010976//positive regulation of neuron projection development;GO:0016573//histone acetylation;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0018393//internal peptidyl-lysine acetylation;GO:0018394//peptidyl-lysine acetylation;GO:0030183//B cell differentiation;GO:0030220//platelet formation;GO:0030324//lung development;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031648//protein destabilization;GO:0032092//positive regulation of protein binding;GO:0034644//cellular response to UV;GO:0035264//multicellular organism growth;GO:0035855//megakaryocyte development;GO:0036268//swimming;GO:0042221//response to chemical;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043627//response to estrogen;GO:0043923//positive regulation by host of viral transcription;GO:0043967//histone H4 acetylation;GO:0043969//histone H2B acetylation;GO:0045444//fat cell differentiation;GO:0045721//negative regulation of gluconeogenesis;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060325//face morphogenesis;GO:0060765//regulation of androgen receptor signaling pathway;GO:0061921//peptidyl-lysine propionylation;GO:0090043//regulation of tubulin deacetylation;GO:0097043//histone H3-K56 acetylation;GO:0140066//peptidyl-lysine crotonylation;GO:0140067//peptidyl-lysine butyrylation;GO:1900034//regulation of cellular response to heat;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1905636//positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding"	--
ENSG00000100395	14.336	14.706	16.594	15.006	14.576	15.944	906	945	757	724	803	722	L3MBTL2	L3MBTL histone methyl-lysine binding protein 2 [Source:HGNC Symbol;Acc:HGNC:18594]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000100399	20.994	24.052	26.167	30.11	34.026	29.623	831	957	611	867	1027	753	CHADL	chondroadherin like [Source:HGNC Symbol;Acc:HGNC:25165]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0098633//collagen fibril binding	GO:0032331//negative regulation of chondrocyte differentiation;GO:1904027//negative regulation of collagen fibril organization	--
ENSG00000100401	28.987	27.546	31.626	32.522	31.007	32.149	2191	2072	1742	1796	1988	1734	RANGAP1	Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14319	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016235//aggresome;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044614//nuclear pore cytoplasmic filaments;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle;GO:0106068//SUMO ligase complex;GO:1904115//axon cytoplasm;GO:1990723//cytoplasmic periphery of the nuclear pore complex"	GO:0003723//RNA binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0031625//ubiquitin protein ligase binding;GO:0045296//cadherin binding	GO:0007165//signal transduction;GO:0016925//protein sumoylation;GO:0046826//negative regulation of protein export from nucleus;GO:0048678//response to axon injury;GO:0050790//regulation of catalytic activity;GO:0051168//nuclear export;GO:0071375//cellular response to peptide hormone stimulus;GO:0090630//activation of GTPase activity;GO:1904117//cellular response to vasopressin	--
ENSG00000100403	56.562	55.729	66.968	72.404	68.611	74.282	6929	6862	6059	6570	7101	6621	ZC3H7B	zinc finger CCCH-type containing 7B [Source:HGNC Symbol;Acc:HGNC:30869]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding	GO:0010608//posttranscriptional regulation of gene expression;GO:0035196//production of miRNAs involved in gene silencing by miRNA	--
ENSG00000100410	14.01	13.346	13.328	14.773	15.933	16.424	306	293	215	239	294	261	PHF5A	PHD finger protein 5A [Source:HGNC Symbol;Acc:HGNC:18000]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12834	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048863//stem cell differentiation"	--
ENSG00000100412	95.442	103.325	107.988	124.626	119.497	115.564	5363.56	5844.22	4498.17	5224.98	5682.01	4738.76	ACO2	aconitase 2 [Source:HGNC Symbol;Acc:HGNC:118]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K01681;K01681;K01681;K01681;K01681;K01681	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0003994//aconitate hydratase activity;GO:0005506//iron ion binding;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0047780//citrate dehydratase activity;GO:0051536//iron-sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0001889//liver development;GO:0006091//generation of precursor metabolites and energy;GO:0006099//tricarboxylic acid cycle;GO:0006101//citrate metabolic process;GO:0006102//isocitrate metabolic process;GO:0035900//response to isolation stress	--
ENSG00000100413	20.845	17.934	19.492	23.71	20.628	22.118	1361.44	1200.78	1106.83	1073.02	1166.99	1089.24	POLR3H	RNA polymerase III subunit H [Source:HGNC Symbol;Acc:HGNC:30349]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03022;K03022	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005813//centrosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0051607//defense response to virus"	--
ENSG00000100416	4.903	5.864	7.364	8.025	7.211	8.083	164	196	176	202	198	198	TRMU	tRNA mitochondrial 2-thiouridylase [Source:HGNC Symbol;Acc:HGNC:25481]	-	-	-	-	GO:0005739//mitochondrion	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0016783//sulfurtransferase activity;GO:0061708//tRNA-5-taurinomethyluridine 2-sulfurtransferase	GO:0002143//tRNA wobble position uridine thiolation;GO:0008033//tRNA processing;GO:0032259//methylation	--
ENSG00000100417	11.451	10.118	10.617	13.206	11.624	9.603	295	262	202	252	253	180	PMM1	phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K17497;K17497;K17497	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043025//neuronal cell body	GO:0004615//phosphomannomutase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0006013//mannose metabolic process;GO:0006487//protein N-linked glycosylation;GO:0009298//GDP-mannose biosynthetic process;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000100418	13.418	14.58	16.561	18.476	17.95	17.705	1052	1149	959	1073	1189	1010	DESI1	desumoylating isopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:24577]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0061676//importin-alpha family protein binding;GO:0070140//SUMO-specific isopeptidase activity	GO:0006508//proteolysis;GO:0006611//protein export from nucleus;GO:0016926//protein desumoylation;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0070646//protein modification by small protein removal	--
ENSG00000100422	37.304	36.206	35.019	34.58	33.62	37.65	3437	3353	2383	2360	2617	2524	CERK	ceramide kinase [Source:HGNC Symbol;Acc:HGNC:19256]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K04715;K04715	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001727//lipid kinase activity;GO:0001729//ceramide kinase activity;GO:0003951//NAD+ kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0102773//dihydroceramide kinase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0016310//phosphorylation;GO:0046834//lipid phosphorylation	--
ENSG00000100425	8.043	8.541	8.423	7.682	9.507	9.126	765	806	572	540	754	613	BRD1	bromodomain containing 1 [Source:HGNC Symbol;Acc:HGNC:1102]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0036409//histone H3-K14 acetyltransferase complex;GO:0043204//perikaryon;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0005515//protein binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035902//response to immobilization stress;GO:0043249//erythrocyte maturation;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0050793//regulation of developmental process;GO:0051602//response to electrical stimulus;GO:1903706//regulation of hemopoiesis"	--
ENSG00000100426	4.749	4.941	5.095	5.099	4.851	4.537	679	710	538	540	586	472	ZBED4	zinc finger BED-type containing 4 [Source:HGNC Symbol;Acc:HGNC:20721]	-	-	-	-	GO:0000785//chromatin;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity"	GO:0045944//positive regulation of transcription by RNA polymerase II	zf-BED
ENSG00000100427	0.195	0.055	0.057	0.075	0.083	0.134	14	4	3	4	5	7	MLC1	modulator of VRAC current 1 [Source:HGNC Symbol;Acc:HGNC:17082]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006811//ion transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032388//positive regulation of intracellular transport;GO:0047484//regulation of response to osmotic stress;GO:0071397//cellular response to cholesterol;GO:0072584//caveolin-mediated endocytosis	--
ENSG00000100429	3.359	3.124	3.321	3.106	3.475	4.875	175	165	123	120	143	189	HDAC10	histone deacetylase 10 [Source:HGNC Symbol;Acc:HGNC:18128]	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K18671;K18671;K18671	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0019899//enzyme binding;GO:0033558//protein deacetylase activity;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0047609//acetylputrescine deacetylase activity;GO:0047611//acetylspermidine deacetylase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006476//protein deacetylation;GO:0006914//autophagy;GO:0006974//cellular response to DNA damage stimulus;GO:0016236//macroautophagy;GO:0016575//histone deacetylation;GO:0032425//positive regulation of mismatch repair;GO:0034983//peptidyl-lysine deacetylation;GO:0035825//homologous recombination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0106047//polyamine deacetylation;GO:0106048//spermidine deacetylation"	--
ENSG00000100433	0	0	0	0	0	0	0	0	0	0	0	0	KCNK10	potassium two pore domain channel subfamily K member 10 [Source:HGNC Symbol;Acc:HGNC:6273]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K04920	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007165//signal transduction;GO:0007613//memory;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000100439	57.583	56.554	58.923	62.302	62.266	62.45	3352	3509	2655	2875	3153	2802	ABHD4	"abhydrolase domain containing 4, N-acyl phospholipase B [Source:HGNC Symbol;Acc:HGNC:20154]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0055088//lipid homeostasis;GO:0070292//N-acylphosphatidylethanolamine metabolic process	--
ENSG00000100441	4.663	4.626	6.602	5.635	7.859	6.124	588.15	578.52	531.71	494.8	537.76	504.17	KHNYN	KH and NYN domain containing [Source:HGNC Symbol;Acc:HGNC:20166]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004521//endoribonuclease activity;GO:0005515//protein binding	"GO:0008150//biological_process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000100442	24.291	22.94	20.79	17.615	17.043	17.413	648.11	623.5	413.91	352.33	390.96	342.13	FKBP3	FKBP prolyl isomerase 3 [Source:HGNC Symbol;Acc:HGNC:3719]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0038023//signaling receptor activity	GO:0000413//protein peptidyl-prolyl isomerization	--
ENSG00000100445	23.77	25.918	31.775	29.879	30.792	33.869	579.85	640.48	536.25	538.2	634.24	571.83	SDR39U1	short chain dehydrogenase/reductase family 39U member 1 [Source:HGNC Symbol;Acc:HGNC:20275]	-	-	-	-	GO:0005634//nucleus	GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity	-	--
ENSG00000100448	0	0	0	0	0	0	0	0	0	0	0	0	CTSG	cathepsin G [Source:HGNC Symbol;Acc:HGNC:2532]	Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems	Signaling molecules and interaction;Immune system;Immune disease;Infectious disease: parasitic;Transport and catabolism;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05146//Amoebiasis;ko04142//Lysosome;ko04614//Renin-angiotensin system	K01319;K01319;K01319;K01319;K01319;K01319	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030141//secretory granule;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0048018//receptor ligand activity;GO:0089720//caspase binding	GO:0002003//angiotensin maturation;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006508//proteolysis;GO:0006955//immune response;GO:0016485//protein processing;GO:0019221//cytokine-mediated signaling pathway;GO:0019731//antibacterial humoral response;GO:0022617//extracellular matrix disassembly;GO:0030168//platelet activation;GO:0032496//response to lipopolysaccharide;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0042119//neutrophil activation;GO:0042742//defense response to bacterium;GO:0044267//cellular protein metabolic process;GO:0050778//positive regulation of immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0050868//negative regulation of T cell activation;GO:0070946//neutrophil-mediated killing of gram-positive bacterium;GO:0071222//cellular response to lipopolysaccharide;GO:0098786//biofilm matrix disassembly;GO:1901731//positive regulation of platelet aggregation	--
ENSG00000100450	0	0	0	0	0	0	0	0	0	0	0	0	GZMH	granzyme H [Source:HGNC Symbol;Acc:HGNC:4710]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044194//cytolytic granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0019835//cytolysis	--
ENSG00000100453	0	0	0	0	0	0	0	0	0	0	0	0	GZMB	granzyme B [Source:HGNC Symbol;Acc:HGNC:4709]	Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Cell growth and death;Immune disease;Immune disease;Endocrine and metabolic disease;Immune disease	ko05202//Transcriptional misregulation in cancer;ko04650//Natural killer cell mediated cytotoxicity;ko04210//Apoptosis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K01353;K01353;K01353;K01353;K01353;K01353;K01353	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044194//cytolytic granule	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0017148//negative regulation of translation;GO:0019835//cytolysis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0070269//pyroptosis;GO:0140507//granzyme-mediated programmed cell death signaling pathway;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	--
ENSG00000100461	39.419	44.559	46.489	49.311	43.285	47.648	1567	1864	1361	1412	1487	1476	RBM23	RNA binding motif protein 23 [Source:HGNC Symbol;Acc:HGNC:20155]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000100462	30.987	30.687	29.193	32.216	38.353	33.459	1387	1456	1019	1041	1224	1120	PRMT5	protein arginine methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:10894]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0034709//methylosome;GO:0035097//histone methyltransferase complex	GO:0002039//p53 binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008327//methyl-CpG binding;GO:0008469//histone-arginine N-methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0070888//E-box binding	"GO:0000387//spliceosomal snRNP assembly;GO:0006325//chromatin organization;GO:0006353//DNA-templated transcription, termination;GO:0006355//regulation of transcription, DNA-templated;GO:0006479//protein methylation;GO:0007088//regulation of mitotic nuclear division;GO:0018216//peptidyl-arginine methylation;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0032259//methylation;GO:0032922//circadian regulation of gene expression;GO:0034969//histone arginine methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0042118//endothelial cell activation;GO:0043985//histone H4-R3 methylation;GO:0044030//regulation of DNA methylation;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0048511//rhythmic process;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0090161//Golgi ribbon formation;GO:0097421//liver regeneration;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904992//positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway"	--
ENSG00000100473	2.097	1.705	1.215	0.448	1.109	0.589	88	72	38	14	22	9	COCH	cochlin [Source:HGNC Symbol;Acc:HGNC:2180]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0005518//collagen binding	GO:0007605//sensory perception of sound;GO:0008360//regulation of cell shape;GO:0042742//defense response to bacterium;GO:0045089//positive regulation of innate immune response	--
ENSG00000100478	2.64	2.529	1.821	3.46	2.749	3.816	128	172	87	102.11	132.13	116.08	AP4S1	adaptor related protein complex 4 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:575]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12403	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030124//AP-4 adaptor complex;GO:0031904//endosome lumen;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	-	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000100479	0.282	0.303	0.509	0.371	0.27	0.377	10	10	8	9	8	9	POLE2	"DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair	K02325;K02325;K02325	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008622//epsilon DNA polymerase complex;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0042276//error-prone translesion synthesis	--
ENSG00000100483	2.681	3.046	3.362	2.707	2.595	3.449	78	91	81	57	61	70	VCPKMT	valosin containing protein lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:20352]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0051117//ATPase binding	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation;GO:0032780//negative regulation of ATPase activity	--
ENSG00000100485	9.574	7.311	6.976	6.989	8.511	8.434	1011	777	521	536	735	610	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:11188]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Cell motility;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Substance dependence;Immune system;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Immune system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04660//T cell receptor signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko05213//Endometrial cancer"	K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0001782//B cell homeostasis;GO:0002260//lymphocyte homeostasis;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0033081//regulation of T cell differentiation in thymus;GO:0042129//regulation of T cell proliferation;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:2000973//regulation of pro-B cell differentiation	--
ENSG00000100490	0.678	0.97	1.165	0.291	0.586	0.855	64.28	75.54	50.19	22.1	45.61	48.53	CDKL1	cyclin dependent kinase like 1 [Source:HGNC Symbol;Acc:HGNC:1781]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0035869//ciliary transition zone;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle;GO:1902017//regulation of cilium assembly	--
ENSG00000100503	3.029	2.519	1.811	1.336	1.201	1.382	497	351	219	146	174	183	NIN	ninein [Source:HGNC Symbol;Acc:HGNC:14906]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0044295//axonal growth cone;GO:0045177//apical part of cell;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole;GO:0097539//ciliary transition fiber;GO:0120103//centriolar subdistal appendage	GO:0000166//nucleotide binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019900//kinase binding;GO:0051011//microtubule minus-end binding	GO:0008104//protein localization;GO:0010457//centriole-centriole cohesion;GO:0021540//corpus callosum morphogenesis;GO:0021957//corticospinal tract morphogenesis;GO:0031116//positive regulation of microtubule polymerization;GO:0034454//microtubule anchoring at centrosome;GO:0048668//collateral sprouting;GO:0050772//positive regulation of axonogenesis;GO:0051642//centrosome localization;GO:0090222//centrosome-templated microtubule nucleation	--
ENSG00000100504	37.401	38.985	37.408	32.189	29.623	35.545	2171	2275	1604	1382	1452	1501	PYGL	glycogen phosphorylase L [Source:HGNC Symbol;Acc:HGNC:9725]	Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cell growth and death;Endocrine system;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04217//Necroptosis;ko04910//Insulin signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00500//Starch and sucrose metabolism	K00688;K00688;K00688;K00688;K00688;K00688	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0000166//nucleotide binding;GO:0002060//purine nucleobase binding;GO:0003824//catalytic activity;GO:0004645//1,4-alpha-oligoglucan phosphorylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008184//glycogen phosphorylase activity;GO:0016208//AMP binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019842//vitamin binding;GO:0030170//pyridoxal phosphate binding;GO:0030246//carbohydrate binding;GO:0032052//bile acid binding;GO:0042802//identical protein binding;GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity"	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0008152//metabolic process;GO:0009617//response to bacterium;GO:0042593//glucose homeostasis;GO:0070266//necroptotic process	--
ENSG00000100505	0.356	0.466	0.25	0.269	0.209	0.302	37	42	17	20	16	17	TRIM9	tripartite motif containing 9 [Source:HGNC Symbol;Acc:HGNC:16288]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000100519	33.831	31.703	32.656	30.032	26.989	29.752	866	787	586	554	558	534	PSMC6	"proteasome 26S subunit, ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9553]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03064;K03064;K03064;K03064;K03064;K03064;K03064;K03064;K03064	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0016234//inclusion body;GO:0022624//proteasome accessory complex;GO:0031597//cytosolic proteasome complex;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0030674//protein-macromolecule adaptor activity;GO:0036402//proteasome-activating activity;GO:0042802//identical protein binding	GO:0006261//DNA-dependent DNA replication;GO:0030163//protein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0044085//cellular component biogenesis;GO:0045899//positive regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0090261//positive regulation of inclusion body assembly;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000100522	8.85	7.683	7.418	9.169	7.896	7.778	703	547	375	416	480	419	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:19980]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K00621;K00621	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0004343//glucosamine 6-phosphate N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding;GO:0048029//monosaccharide binding	GO:0006048//UDP-N-acetylglucosamine biosynthetic process	--
ENSG00000100523	3.251	3.144	3.483	2.531	2.65	2.681	348	277	206	173	223	217	DDHD1	DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004620//phospholipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0090141//positive regulation of mitochondrial fission	--
ENSG00000100526	8.961	12.904	10.517	5.217	3.936	7.654	155	221	122	65	58	84	CDKN3	cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000100528	152.097	138.279	133.972	138.003	126.852	131.587	3349	3022	2108	1972	2158	1986	CNIH1	cornichon family AMPA receptor auxiliary protein 1 [Source:HGNC Symbol;Acc:HGNC:19431]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0016192//vesicle-mediated transport	--
ENSG00000100532	8.396	5.935	6.188	5.471	4.915	6.419	292	232	186	137	151	182	CGRRF1	cell growth regulator with ring finger domain 1 [Source:HGNC Symbol;Acc:HGNC:15528]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0030308//negative regulation of cell growth	--
ENSG00000100554	43.051	44.207	42.167	40.752	38.215	38.095	1315	1379	983	925	984	819	ATP6V1D	ATPase H+ transporting V1 subunit D [Source:HGNC Symbol;Acc:HGNC:13527]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02149;K02149;K02149;K02149;K02149;K02149;K02149;K02149;K02149;K02149	"GO:0000139//Golgi membrane;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0016241//regulation of macroautophagy;GO:0030030//cell projection organization;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000100557	0	0.047	0	0	0	0	0	1	0	0	0	0	CCDC198	coiled-coil domain containing 198 [Source:HGNC Symbol;Acc:HGNC:20189]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000100558	0.287	0.254	0.117	0.719	0.226	0.387	9	8	2	9	6	8	PLEK2	pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031258//lamellipodium membrane;GO:0042995//cell projection	"GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0030036//actin cytoskeleton organization;GO:0031346//positive regulation of cell projection organization;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0120034//positive regulation of plasma membrane bounded cell projection assembly	--
ENSG00000100564	15.928	13.584	18.116	17.374	14.321	16.884	412.96	361.44	331.65	317	294	321.52	PIGH	phosphatidylinositol glycan anchor biosynthesis class H [Source:HGNC Symbol;Acc:HGNC:8964]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03858;K03858	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006464//cellular protein modification process;GO:0006506//GPI anchor biosynthetic process	--
ENSG00000100565	0	0	0	0	0	0	0	0	0	0	0	0	LRRC74A	leucine rich repeat containing 74A [Source:HGNC Symbol;Acc:HGNC:23346]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000100567	22.768	20.642	25.544	25.053	21.197	21.786	451	411	362	364	352	312	PSMA3	proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02727;K02727;K02727;K02727;K02727;K02727;K02727;K02727	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0045202//synapse;GO:0070062//extracellular exosome"	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0052548//regulation of endopeptidase activity;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000100568	48.855	48.921	46.421	46.15	43.363	44.879	2983.34	2626.63	2013.67	1810.58	2023.06	1881.64	VTI1B	vesicle transport through interaction with t-SNAREs 1B [Source:HGNC Symbol;Acc:HGNC:17793]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08493	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031093//platelet alpha granule lumen;GO:0031201//SNARE complex;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019869//chloride channel inhibitor activity	"GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006896//Golgi to vacuole transport;GO:0006904//vesicle docking involved in exocytosis;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016236//macroautophagy;GO:0042147//retrograde transport, endosome to Golgi;GO:0048280//vesicle fusion with Golgi apparatus;GO:0061025//membrane fusion;GO:1903076//regulation of protein localization to plasma membrane"	--
ENSG00000100575	16.01	15.054	14.449	15.219	13.825	13.116	319	286	225	209	212	231	TIMM9	translocase of inner mitochondrial membrane 9 [Source:HGNC Symbol;Acc:HGNC:11819]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0032977//membrane insertase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000100577	11.127	12.969	11.894	13.3	15.075	14.084	253	299	204	227	291	220	GSTZ1	glutathione S-transferase zeta 1 [Source:HGNC Symbol;Acc:HGNC:4643]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K01800;K01800	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016034//maleylacetoacetate isomerase activity;GO:0016740//transferase activity;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006559//L-phenylalanine catabolic process;GO:0006572//tyrosine catabolic process;GO:0006749//glutathione metabolic process;GO:0008152//metabolic process;GO:0009072//aromatic amino acid family metabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000100578	2.613	1.973	1.832	1.441	1.432	2.142	275	210	145	113	143	149	KIAA0586	KIAA0586 [Source:HGNC Symbol;Acc:HGNC:19960]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:0070201//regulation of establishment of protein localization	--
ENSG00000100580	8.063	7.565	8.285	8.026	8.242	9.75	1298	1224	985	957	1121	1142	TMED8	transmembrane p24 trafficking protein family member 8 [Source:HGNC Symbol;Acc:HGNC:18633]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000100583	0.969	1.23	0.875	1.071	0.478	0.511	60	68	40	24	25	23	SAMD15	sterile alpha motif domain containing 15 [Source:HGNC Symbol;Acc:HGNC:18631]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000100591	60.053	62.558	64.571	60.762	59.067	61.749	1617	1681	1285	1215	1351	1218	AHSA1	activator of HSP90 ATPase activity 1 [Source:HGNC Symbol;Acc:HGNC:1189]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding	GO:0006457//protein folding;GO:0032781//positive regulation of ATPase activity	--
ENSG00000100592	20.48	15.147	15.749	11.426	15.463	15.57	2502	1860	1421	1034	1596	1384	DAAM1	dishevelled associated activator of morphogenesis 1 [Source:HGNC Symbol;Acc:HGNC:18142]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04512	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	"GO:0016043//cellular component organization;GO:0016055//Wnt signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0060071//Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000100593	1.047	0.587	1.165	0.69	0.997	0.925	51	36	33	28	44	35	ISM2	isthmin 2 [Source:HGNC Symbol;Acc:HGNC:23176]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000100596	12.968	11.427	12.643	10.459	11.99	12.347	2161	1914	1556	1291	1688	1497	SPTLC2	serine palmitoyltransferase long chain base subunit 2 [Source:HGNC Symbol;Acc:HGNC:11278]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K00654;K00654;K00654	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex	GO:0003824//catalytic activity;GO:0004758//serine C-palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0009058//biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046511//sphinganine biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0060612//adipose tissue development;GO:1904504//positive regulation of lipophagy	--
ENSG00000100599	2.622	2.834	3.421	3.779	3.593	3.112	207	224	198	210	220	181	RIN3	Ras and Rab interactor 3 [Source:HGNC Symbol;Acc:HGNC:18751]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043025//neuronal cell body	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0002091//negative regulation of receptor internalization;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:0060755//negative regulation of mast cell chemotaxis;GO:0097494//regulation of vesicle size	--
ENSG00000100600	102.007	102.881	99.683	84.603	88.112	79.03	4092	4163	2917	2515	2989	2264	LGMN	legumain [Source:HGNC Symbol;Acc:HGNC:9472]	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04142//Lysosome;ko04612//Antigen processing and presentation	K01369;K01369	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005770//late endosome;GO:0036021//endolysosome lumen;GO:0043202//lysosomal lumen;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0048156//tau protein binding	GO:0003014//renal system process;GO:0006508//proteolysis;GO:0006624//vacuolar protein processing;GO:0007613//memory;GO:0008284//positive regulation of cell population proliferation;GO:0008306//associative learning;GO:0010447//response to acidic pH;GO:0010629//negative regulation of gene expression;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0032801//receptor catabolic process;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0040015//negative regulation of multicellular organism growth;GO:0042359//vitamin D metabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045931//positive regulation of mitotic cell cycle;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071277//cellular response to calcium ion;GO:0090026//positive regulation of monocyte chemotaxis;GO:0097061//dendritic spine organization;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0097264//self proteolysis;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1901185//negative regulation of ERBB signaling pathway;GO:1904646//cellular response to amyloid-beta;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000100601	4.575	4.588	6.01	5.156	4.862	4.537	223	227	227	188	206	173	ALKBH1	"alkB homolog 1, histone H2A dioxygenase [Source:HGNC Symbol;Acc:HGNC:17911]"	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum	GO:0000049//tRNA binding;GO:0003824//catalytic activity;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0016829//lyase activity;GO:0035515//oxidative RNA demethylase activity;GO:0035516//oxidative DNA demethylase activity;GO:0042056//chemoattractant activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0070579//methylcytosine dioxygenase activity;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:1990984//tRNA demethylase activity	GO:0001701//in utero embryonic development;GO:0001764//neuron migration;GO:0001890//placenta development;GO:0002101//tRNA wobble cytosine modification;GO:0006281//DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0006448//regulation of translational elongation;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0035513//oxidative RNA demethylation;GO:0035552//oxidative single-stranded DNA demethylation;GO:0042245//RNA repair;GO:0043524//negative regulation of neuron apoptotic process;GO:0048589//developmental growth;GO:0050918//positive chemotaxis;GO:0070129//regulation of mitochondrial translation;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:1990983//tRNA demethylation	--
ENSG00000100603	22.18	20.65	19.316	17.849	16.333	16.666	939	903	630	567	601	499	SNW1	SNW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16696]	Human Diseases;Human Diseases;Genetic Information Processing;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Transcription;Signal transduction	ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko03040//Spliceosome;ko04330//Notch signaling pathway	K06063;K06063;K06063;K06063	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0042809//vitamin D receptor binding;GO:0042974//retinoic acid receptor binding;GO:0046332//SMAD binding;GO:0050681//androgen receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000398//mRNA splicing, via spliceosome;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043923//positive regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0048384//retinoic acid receptor signaling pathway;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0050769//positive regulation of neurogenesis;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:0071300//cellular response to retinoic acid"	--
ENSG00000100604	0	0.024	0	0	0	0	0	1	0	0	0	0	CHGA	chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0042583//chromaffin granule;GO:0048471//perinuclear region of cytoplasm;GO:0098992//neuronal dense core vesicle	-	GO:0002026//regulation of the force of heart contraction;GO:0002551//mast cell chemotaxis;GO:0006996//organelle organization;GO:0008217//regulation of blood pressure;GO:0031640//killing of cells of other organism;GO:0033366//protein localization to secretory granule;GO:0033604//negative regulation of catecholamine secretion;GO:0042742//defense response to bacterium;GO:0043303//mast cell degranulation;GO:0045087//innate immune response;GO:0045576//mast cell activation;GO:0046676//negative regulation of insulin secretion;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0060452//positive regulation of cardiac muscle contraction;GO:0086030//adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation;GO:1900738//positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway;GO:1901215//negative regulation of neuron death;GO:1901899//positive regulation of relaxation of cardiac muscle;GO:2000707//positive regulation of dense core granule biogenesis	--
ENSG00000100605	81.017	88.071	82.928	83.602	96.655	82.294	3569	3916	2693	2737	3393	2550	ITPK1	inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00913;K00913;K00913	GO:0005829//cytosol;GO:0016324//apical plasma membrane	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000825//inositol tetrakisphosphate 6-kinase activity;GO:0003824//catalytic activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0047325//inositol tetrakisphosphate 1-kinase activity;GO:0052725//inositol-1,3,4-trisphosphate 6-kinase activity;GO:0052726//inositol-1,3,4-trisphosphate 5-kinase activity"	GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0016310//phosphorylation;GO:0021915//neural tube development;GO:0032957//inositol trisphosphate metabolic process;GO:0052746//inositol phosphorylation;GO:0070266//necroptotic process	--
ENSG00000100612	19.944	19.162	21.781	20.266	19.336	20.545	595.69	596.74	480.82	446.94	493.84	444.78	DHRS7	dehydrogenase/reductase 7 [Source:HGNC Symbol;Acc:HGNC:21524]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650//NADP-retinol dehydrogenase activity"	GO:0042572//retinol metabolic process	--
ENSG00000100614	16.123	15.86	15.238	15.568	12.528	14.863	1040	892	646	608	674	656	PPM1A	"protein phosphatase, Mg2+/Mn2+ dependent 1A [Source:HGNC Symbol;Acc:HGNC:9275]"	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04457	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030145//manganese ion binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0070412//R-SMAD binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006470//protein dephosphorylation;GO:0006499//N-terminal protein myristoylation;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0016311//dephosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046827//positive regulation of protein export from nucleus;GO:0051726//regulation of cell cycle;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling"	--
ENSG00000100625	3.068	3.152	2.062	1.434	1.804	2.146	346	313	185	143	178	146	SIX4	SIX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:10890]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15615	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0008582//regulation of synaptic assembly at neuromuscular junction;GO:0008584//male gonad development;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0030238//male sex determination;GO:0030910//olfactory placode formation;GO:0032880//regulation of protein localization;GO:0034504//protein localization to nucleus;GO:0042472//inner ear morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043586//tongue development;GO:0045214//sarcomere organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046661//male sex differentiation;GO:0048538//thymus development;GO:0048699//generation of neurons;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048856//anatomical structure development;GO:0050678//regulation of epithelial cell proliferation;GO:0051451//myoblast migration;GO:0060037//pharyngeal system development;GO:0061055//myotome development;GO:0061197//fungiform papilla morphogenesis;GO:0061551//trigeminal ganglion development;GO:0072075//metanephric mesenchyme development;GO:0072095//regulation of branch elongation involved in ureteric bud branching;GO:0072107//positive regulation of ureteric bud formation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0098528//skeletal muscle fiber differentiation;GO:1902725//negative regulation of satellite cell differentiation"	Homeobox
ENSG00000100626	0.169	0.17	0.13	0.213	0.298	0.065	15	13	5	14	23	4	GALNT16	polypeptide N-acetylgalactosaminyltransferase 16 [Source:HGNC Symbol;Acc:HGNC:23233]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine	--
ENSG00000100628	0.018	0.018	0	0	0.03	0	1	1	0	0	1	0	ASB2	ankyrin repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:16012]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030018//Z disc	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity;GO:0097602//cullin family protein binding	GO:0001947//heart looping;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0014732//skeletal muscle atrophy;GO:0016567//protein ubiquitination;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0035914//skeletal muscle cell differentiation;GO:0036336//dendritic cell migration;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043687//post-translational protein modification;GO:0055007//cardiac muscle cell differentiation;GO:0055013//cardiac muscle cell development;GO:0071800//podosome assembly	--
ENSG00000100629	0.734	0.82	0.138	0.277	0.221	0.496	57	40	7	19	17	22	CEP128	centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0120103//centriolar subdistal appendage	-	GO:0008104//protein localization	--
ENSG00000100632	47.114	44.933	55.044	49.37	36.937	46.785	773	741	667	600	512	558	ERH	ERH mRNA splicing and mitosis factor [Source:HGNC Symbol;Acc:HGNC:3447]	-	-	-	-	GO:0005634//nucleus;GO:0030496//midbody;GO:0034709//methylosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding	GO:0006139//nucleobase-containing compound metabolic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0007049//cell cycle	--
ENSG00000100644	73.338	58.503	47.78	45.838	53.183	63.8	5974	4779	2877	2770	3664	3781	HIF1A	hypoxia inducible factor 1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:4910]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: overview;Infectious disease: viral;Transport and catabolism;Endocrine system;Signal transduction;Immune system;Cancer: overview;Cancer: overview;Transport and catabolism;Cancer: specific types;Cancer: overview	ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko04919//Thyroid hormone signaling pathway;ko04066//HIF-1 signaling pathway;ko04659//Th17 cell differentiation;ko05231//Choline metabolism in cancer;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma;ko05230//Central carbon metabolism in cancer	K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268;K08268	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0031514//motile cilium;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1904115//axon cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding"	"GO:0000302//response to reactive oxygen species;GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001666//response to hypoxia;GO:0001678//cellular glucose homeostasis;GO:0001755//neural crest cell migration;GO:0001837//epithelial to mesenchymal transition;GO:0001892//embryonic placenta development;GO:0001922//B-1 B cell homeostasis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0002052//positive regulation of neuroblast proliferation;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0003151//outflow tract morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0006089//lactate metabolic process;GO:0006110//regulation of glycolytic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006879//cellular iron ion homeostasis;GO:0007165//signal transduction;GO:0007595//lactation;GO:0008542//visual learning;GO:0010039//response to iron ion;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0010573//vascular endothelial growth factor production;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0014850//response to muscle activity;GO:0016239//positive regulation of macroautophagy;GO:0019896//axonal transport of mitochondrion;GO:0021502//neural fold elevation formation;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030279//negative regulation of ossification;GO:0030502//negative regulation of bone mineralization;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032007//negative regulation of TOR signaling;GO:0032364//oxygen homeostasis;GO:0032722//positive regulation of chemokine production;GO:0032909//regulation of transforming growth factor beta2 production;GO:0032963//collagen metabolic process;GO:0033554//cellular response to stress;GO:0035162//embryonic hemopoiesis;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042127//regulation of cell population proliferation;GO:0042541//hemoglobin biosynthetic process;GO:0042593//glucose homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045821//positive regulation of glycolytic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045926//negative regulation of growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046716//muscle cell cellular homeostasis;GO:0046886//positive regulation of hormone biosynthetic process;GO:0048514//blood vessel morphogenesis;GO:0048546//digestive tract morphogenesis;GO:0048593//camera-type eye morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051216//cartilage development;GO:0051541//elastin metabolic process;GO:0060574//intestinal epithelial cell maturation;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0061072//iris morphogenesis;GO:0061298//retina vasculature development in camera-type eye;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070101//positive regulation of chemokine-mediated signaling pathway;GO:0070243//regulation of thymocyte apoptotic process;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0071347//cellular response to interleukin-1;GO:0071456//cellular response to hypoxia;GO:0071542//dopaminergic neuron differentiation;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:0098586//cellular response to virus;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903377//negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903599//positive regulation of autophagy of mitochondrion;GO:1903715//regulation of aerobic respiration;GO:2000273//positive regulation of signaling receptor activity;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000434//regulation of protein neddylation;GO:2001054//negative regulation of mesenchymal cell apoptotic process"	Others
ENSG00000100647	5.179	5.437	4.869	5.543	5.569	5.815	579	611	402	459	526	473	SUSD6	sushi domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19956]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0008219//cell death	--
ENSG00000100650	94.365	86.753	91.986	87.275	97.838	116.647	2514	2412	1889	1702	2188	2263	SRSF5	serine and arginine rich splicing factor 5 [Source:HGNC Symbol;Acc:HGNC:10787]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K12893;K12893	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043422//protein kinase B binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001889//liver development;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0033120//positive regulation of RNA splicing;GO:0051726//regulation of cell cycle;GO:0097421//liver regeneration"	--
ENSG00000100652	0	0	0	0.098	0	0	0	0	0	3	0	0	SLC10A1	solute carrier family 10 member 1 [Source:HGNC Symbol;Acc:HGNC:10905]	Human Diseases;Organismal Systems	Infectious disease: viral;Digestive system	ko05161//Hepatitis B;ko04976//Bile secretion	K14341;K14341	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0008508//bile acid:sodium symporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0010468//regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0031667//response to nutrient levels;GO:0038183//bile acid signaling pathway;GO:0045471//response to ethanol;GO:0046718//viral entry into host cell;GO:0055085//transmembrane transport;GO:0071466//cellular response to xenobiotic stimulus;GO:0120188//regulation of bile acid secretion;GO:1904486//response to 17alpha-ethynylestradiol	--
ENSG00000100664	54.757	51.744	49.695	34.978	43.835	37.819	3294	3225	2134	1674	2168	1805	EIF5	eukaryotic translation initiation factor 5 [Source:HGNC Symbol;Acc:HGNC:3299]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding;GO:0071074//eukaryotic initiation factor eIF2 binding	GO:0001731//formation of translation preinitiation complex;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0050790//regulation of catalytic activity	--
ENSG00000100665	0	0	0	0	0	0	0	0	0	0	0	0	SERPINA4	serpin family A member 4 [Source:HGNC Symbol;Acc:HGNC:8948]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031089//platelet dense granule lumen;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000100678	0	0.018	0	0	0.023	0	0	1	0	0	2	0	SLC8A3	solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]	Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Sensory system;Signal transduction;Signal transduction;Cardiovascular disease;Circulatory system;Signal transduction;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease;Digestive system;Excretory system	ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04974//Protein digestion and absorption;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016528//sarcoplasm;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031226//intrinsic component of plasma membrane;GO:0031594//neuromuscular junction;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse	GO:0005432//calcium:sodium antiporter activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015297//antiporter activity;GO:0015368//calcium:cation antiporter activity;GO:0015491//cation:cation antiporter activity;GO:0046872//metal ion binding;GO:0099580//ion antiporter activity involved in regulation of postsynaptic membrane potential	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0007154//cell communication;GO:0007611//learning or memory;GO:0007612//learning;GO:0007613//memory;GO:0014819//regulation of skeletal muscle contraction;GO:0030001//metal ion transport;GO:0035725//sodium ion transmembrane transport;GO:0042552//myelination;GO:0048709//oligodendrocyte differentiation;GO:0050808//synapse organization;GO:0051560//mitochondrial calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0070588//calcium ion transmembrane transport;GO:0071456//cellular response to hypoxia;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0098703//calcium ion import across plasma membrane;GO:0098815//modulation of excitatory postsynaptic potential;GO:1903779//regulation of cardiac conduction	--
ENSG00000100697	11.96	10.249	9.931	7.36	9.234	8.762	2483	2137	1493	1094	1541	1322	DICER1	"dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098]"	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K11592	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0033167//ARC complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0070578//RISC-loading complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004525//ribonuclease III activity;GO:0004530//deoxyribonuclease I activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0019904//protein domain specific binding;GO:0035197//siRNA binding;GO:0046872//metal ion binding;GO:0070883//pre-miRNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006309//apoptotic DNA fragmentation;GO:0006396//RNA processing;GO:0010586//miRNA metabolic process;GO:0010626//negative regulation of Schwann cell proliferation;GO:0010629//negative regulation of gene expression;GO:0014040//positive regulation of Schwann cell differentiation;GO:0016078//tRNA catabolic process;GO:0021675//nerve development;GO:0030422//production of siRNA involved in RNA interference;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0031643//positive regulation of myelination;GO:0032290//peripheral nervous system myelin formation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035087//siRNA loading onto RISC involved in RNA interference;GO:0035194//post-transcriptional gene silencing by RNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0036404//conversion of ds siRNA to ss siRNA;GO:0038061//NIK/NF-kappaB signaling;GO:0048812//neuron projection morphogenesis;GO:0070918//production of small RNA involved in gene silencing by RNA;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000100711	32.159	34.258	32.202	26.644	26.333	27.05	914.16	995.3	679.85	564.48	634.59	573.28	ZFYVE21	zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760]	-	-	-	-	GO:0005768//endosome;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000100714	22.637	23.554	23.645	24.398	22.298	22.858	1480	1546	1140	1165	1223	1077.96	MTHFD1	"methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K00288;K00288	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity;GO:0016874//ligase activity	GO:0000105//histidine biosynthetic process;GO:0001780//neutrophil homeostasis;GO:0001843//neural tube closure;GO:0006164//purine nucleotide biosynthetic process;GO:0006555//methionine metabolic process;GO:0006730//one-carbon metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0007507//heart development;GO:0008152//metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009069//serine family amino acid metabolic process;GO:0009070//serine family amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009257//10-formyltetrahydrofolate biosynthetic process;GO:0019346//transsulfuration;GO:0035999//tetrahydrofolate interconversion;GO:0048702//embryonic neurocranium morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0061053//somite development	--
ENSG00000100721	0	0	0	0	0	0	0	0	0	0	0	0	TCL1A	TCL1 family AKT coactivator A [Source:HGNC Symbol;Acc:HGNC:11648]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K10167	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0031334//positive regulation of protein-containing complex assembly;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0071356//cellular response to tumor necrosis factor;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000100722	22.458	20.818	18.827	15.359	18.233	17.677	1360.51	1151.79	848.06	652.86	941.42	787.38	ZC3H14	zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0032839//dendrite cytoplasm;GO:1904115//axon cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0046872//metal ion binding	GO:0043488//regulation of mRNA stability;GO:1900364//negative regulation of mRNA polyadenylation	--
ENSG00000100726	7.152	10.057	8.468	8.65	9.247	7.958	485	678	425	429	531	396	TELO2	telomere maintenance 2 [Source:HGNC Symbol;Acc:HGNC:29099]	Environmental Information Processing;Genetic Information Processing	Signal transduction;Replication and repair	ko04150//mTOR signaling pathway;ko03460//Fanconi anemia pathway	K11137;K11137	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0034399//nuclear periphery;GO:0070209//ASTRA complex;GO:0110078//TTT complex"	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042162//telomeric DNA binding;GO:0044877//protein-containing complex binding;GO:0051879//Hsp90 protein binding;GO:0060090//molecular adaptor activity	GO:0007004//telomere maintenance via telomerase;GO:0032006//regulation of TOR signaling;GO:0050821//protein stabilization;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1904263//positive regulation of TORC1 signaling;GO:1904515//positive regulation of TORC2 signaling;GO:2000003//positive regulation of DNA damage checkpoint	--
ENSG00000100731	18.226	15.81	15.258	11.685	13.404	13.443	3686	3302	2309	1768	2227	2011	PCNX1	pecanex 1 [Source:HGNC Symbol;Acc:HGNC:19740]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000100739	1.742	1.364	0.803	3.102	1.907	2.292	47	37	16	62	43.48	45	BDKRB1	bradykinin receptor B1 [Source:HGNC Symbol;Acc:HGNC:1029]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cell motility;Sensory system;Immune system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04750//Inflammatory mediator regulation of TRP channels;ko04610//Complement and coagulation cascades	K03915;K03915;K03915;K03915;K03915;K03915	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004947//bradykinin receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding	GO:0001933//negative regulation of protein phosphorylation;GO:0002687//positive regulation of leukocyte migration;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0016477//cell migration;GO:0019233//sensory perception of pain;GO:0030308//negative regulation of cell growth;GO:0032496//response to lipopolysaccharide;GO:0045776//negative regulation of blood pressure;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol	--
ENSG00000100744	10.946	8.956	9.764	10.511	9.791	12.604	504	412	328	355	376	415	GSKIP	GSK3B interacting protein [Source:HGNC Symbol;Acc:HGNC:20343]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0019207//kinase regulator activity;GO:0019901//protein kinase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0051018//protein kinase A binding	GO:0006469//negative regulation of protein kinase activity;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0030111//regulation of Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000100749	3.56	3.678	2.747	2.222	2.689	3.129	158.33	136.98	83.76	71.66	112.59	91.99	VRK1	VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005795//Golgi stack;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0035175//histone kinase activity (H3-S10 specific);GO:0042393//histone binding;GO:0072354//histone kinase activity (H3-T3 specific);GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007077//mitotic nuclear membrane disassembly;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0046777//protein autophosphorylation;GO:0051301//cell division;GO:0090166//Golgi disassembly;GO:0120187//positive regulation of protein localization to chromatin	--
ENSG00000100764	42.652	43.44	42.147	38.505	35.29	35.013	1630.87	1626.29	1208.65	1064.3	1129.17	1028.58	PSMC1	"proteasome 26S subunit, ATPase 1 [Source:HGNC Symbol;Acc:HGNC:9547]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03062;K03062;K03062;K03062;K03062;K03062;K03062;K03062;K03062;K03062;K03062	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0043229//intracellular organelle"	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017025//TBP-class protein binding;GO:0036402//proteasome-activating activity	GO:0006261//DNA-dependent DNA replication;GO:0030163//protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0044085//cellular component biogenesis;GO:1901215//negative regulation of neuron death;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000100767	1.97	2.554	2.513	3.301	3.554	2.614	223	287	192	276	332	201	PAPLN	"papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262]"	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0006508//proteolysis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030198//extracellular matrix organization	--
ENSG00000100784	1.21	1.783	1.546	1.196	0.959	1.354	114.24	90	71.26	74	75	57	RPS6KA5	ribosomal protein S6 kinase A5 [Source:HGNC Symbol;Acc:HGNC:10434]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: bacterial;Cancer: overview;Circulatory system;Nervous system;Signal transduction;Environmental adaptation;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05131//Shigellosis;ko05206//MicroRNAs in cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko04722//Neurotrophin signaling pathway;ko04668//TNF signaling pathway;ko04713//Circadian entrainment;ko05219//Bladder cancer	K04445;K04445;K04445;K04445;K04445;K04445;K04445;K04445;K04445	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0001818//negative regulation of cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007411//axon guidance;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033129//positive regulation of histone phosphorylation;GO:0035066//positive regulation of histone acetylation;GO:0035556//intracellular signal transduction;GO:0043987//histone H3-S10 phosphorylation;GO:0043988//histone H3-S28 phosphorylation;GO:0043990//histone H2A-S1 phosphorylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070498//interleukin-1-mediated signaling pathway"	--
ENSG00000100796	18.889	15.269	17.433	11.632	15.79	16.309	1377	1133	848	657	902	876	PPP4R3A	protein phosphatase 4 regulatory subunit 3A [Source:HGNC Symbol;Acc:HGNC:20219]	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K17491	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0030289//protein phosphatase 4 complex	GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0050790//regulation of catalytic activity	--
ENSG00000100802	5.524	7.22	5.085	6.532	6.774	5.709	206	193	126	152	166	127	C14orf93	chromosome 14 open reading frame 93 [Source:HGNC Symbol;Acc:HGNC:20162]	-	-	-	-	GO:0005576//extracellular region	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0048856//anatomical structure development	--
ENSG00000100804	95.422	104.538	116.901	118.556	104.57	125.443	2065	2251	1851	1873	1903	1929	PSMB5	proteasome 20S subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:9542]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02737;K02737;K02737;K02737;K02737;K02737;K02737;K02737	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006979//response to oxidative stress;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000100811	22.459	19.78	21.708	20.341	19.819	22.433	2718	2491	1885	1837	1947	1879	YY1	YY1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12856]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005677//chromatin silencing complex;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0031011//Ino80 complex;GO:0031519//PcG protein complex	"GO:0000400//four-way junction DNA binding;GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006403//RNA localization;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0009952//anterior/posterior pattern specification;GO:0010225//response to UV-C;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0032688//negative regulation of interferon-beta production;GO:0033044//regulation of chromosome organization;GO:0034644//cellular response to UV;GO:0034696//response to prostaglandin F;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0048468//cell development;GO:0048593//camera-type eye morphogenesis;GO:0051276//chromosome organization;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0071347//cellular response to interleukin-1;GO:0071707//immunoglobulin heavy chain V-D-J recombination;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	zf-C2H2
ENSG00000100813	30.369	32.571	35.005	29.769	30.088	33.328	2351	2460	1962	1635	1878	1698	ACIN1	apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12875;K12875;K12875	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0061574//ASAP complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding	"GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0030218//erythrocyte differentiation;GO:0030263//apoptotic chromosome condensation;GO:0043065//positive regulation of apoptotic process;GO:0045657//positive regulation of monocyte differentiation;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000100814	19.698	22.042	21.184	23.298	19.954	21.391	598	660	477	505	509	453	CCNB1IP1	cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001825//blastocyst formation;GO:0007131//reciprocal meiotic recombination;GO:0007286//spermatid development;GO:0016567//protein ubiquitination;GO:0051026//chiasma assembly;GO:0051321//meiotic cell cycle	--
ENSG00000100815	3.138	1.912	1.713	2.257	1.939	2.124	593	322	237	156	256	258	TRIP11	thyroid hormone receptor interactor 11 [Source:HGNC Symbol;Acc:HGNC:12305]	-	-	-	-	GO:0000139//Golgi membrane;GO:0002079//inner acrosomal membrane;GO:0002080//acrosomal membrane;GO:0002081//outer acrosomal membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030133//transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0003281//ventricular septum development;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0006366//transcription by RNA polymerase II;GO:0006486//protein glycosylation;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051216//cartilage development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060348//bone development;GO:0090161//Golgi ribbon formation;GO:0099041//vesicle tethering to Golgi"	--
ENSG00000100823	119.541	119.344	116.438	130.508	118.007	114.987	3411	3483	2471	2743	2891	2419	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:587]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10771	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005840//ribosome;GO:0016607//nuclear speck;GO:0048471//perinuclear region of cytoplasm"	"GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004521//endoribonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0004527//exonuclease activity;GO:0004528//phosphodiesterase I activity;GO:0004844//uracil DNA N-glycosylase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008309//double-stranded DNA exodeoxyribonuclease activity;GO:0008311//double-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity;GO:0016890//site-specific endodeoxyribonuclease activity, specific for altered base;GO:0031490//chromatin DNA binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0052720//class II DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0090580//phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands;GO:0140431//DNA-(abasic site) binding"	"GO:0000723//telomere maintenance;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006287//base-excision repair, gap-filling;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0010243//response to organonitrogen compound;GO:0014912//negative regulation of smooth muscle cell migration;GO:0042981//regulation of apoptotic process;GO:0043488//regulation of mRNA stability;GO:0045454//cell redox homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070301//cellular response to hydrogen peroxide;GO:0071320//cellular response to cAMP;GO:0071375//cellular response to peptide hormone stimulus;GO:0071417//cellular response to organonitrogen compound;GO:0080111//DNA demethylation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0097698//telomere maintenance via base-excision repair;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000100836	27.329	25.79	29.608	28.947	27.686	36.428	889.7	841.49	679.01	707.25	748.17	804.66	PABPN1	poly(A) binding protein nuclear 1 [Source:HGNC Symbol;Acc:HGNC:8565]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05164//Influenza A;ko03015//mRNA surveillance pathway	K14396;K14396	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0042405//nuclear inclusion body;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0070063//RNA polymerase binding	GO:0000165//MAPK cascade;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006936//muscle contraction;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0071222//cellular response to lipopolysaccharide;GO:1904247//positive regulation of polynucleotide adenylyltransferase activity	--
ENSG00000100842	10.022	7.785	10.603	9.471	9.698	11.996	555	433	434	389	453	483	EFS	embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019904//protein domain specific binding	GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0090527//actin filament reorganization	--
ENSG00000100852	35.286	21.681	22.737	17.871	20.077	24.413	3630	2322	1658	1435	1782	1751	ARHGAP5	Rho GTPase activating protein 5 [Source:HGNC Symbol;Acc:HGNC:675]	Cellular Processes;Organismal Systems	Cellular community - eukaryotes;Immune system	ko04510//Focal adhesion;ko04670//Leukocyte transendothelial migration	K13709;K13709	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042169//SH2 domain binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0030879//mammary gland development;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000100865	16.702	17.014	13.449	17.084	14.7	14.212	405.02	388.75	269.16	306.65	305.97	284.28	CINP	cyclin dependent kinase 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:23789]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0016301//kinase activity	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0051301//cell division	--
ENSG00000100867	0	0.065	0.117	0.092	0.068	0	0	2	3	2	1	0	DHRS2	dehydrogenase/reductase 2 [Source:HGNC Symbol;Acc:HGNC:18349]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0008207//C21-steroid hormone metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0009636//response to toxic substance;GO:0022900//electron transport chain;GO:0034599//cellular response to oxidative stress;GO:0043011//myeloid dendritic cell differentiation;GO:0043066//negative regulation of apoptotic process	--
ENSG00000100883	25.299	23.484	23.021	19.459	19.852	21.342	1155	1066	766	651	765	706	SRP54	signal recognition particle 54 [Source:HGNC Symbol;Acc:HGNC:11301]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03106	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0048500//signal recognition particle"	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008312//7S RNA binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0030942//endoplasmic reticulum signal peptide binding;GO:0043021//ribonucleoprotein complex binding	"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0006617//SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition;GO:0030593//neutrophil chemotaxis;GO:0030851//granulocyte differentiation;GO:0031017//exocrine pancreas development;GO:0045047//protein targeting to ER"	--
ENSG00000100884	0	0	0	0	0	0	0	0	0	0	0	0	CPNE6	copine 6 [Source:HGNC Symbol;Acc:HGNC:2319]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045334//clathrin-coated endocytic vesicle;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0030154//cell differentiation;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000100888	16.652	14.925	15.556	12.37	12.714	11.732	2500	2477	1748	1420	1751	1376	CHD8	chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04494	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:0071339//MLL1 complex	"GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008013//beta-catenin binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0070016//armadillo repeat domain binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001964//startle response;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007420//brain development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032508//DNA duplex unwinding;GO:0035176//social behavior;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0048565//digestive tract development;GO:0060134//prepulse inhibition;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000270//negative regulation of fibroblast apoptotic process"	--
ENSG00000100889	4.31	3.783	3.315	3.865	4.255	7.495	158	155	107	126	149	238	PCK2	"phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725]"	Metabolism;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Carbohydrate metabolism;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism;Excretory system	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko04920//Adipocytokine signaling pathway;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle);ko04964//Proximal tubule bicarbonate reclamation	K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004611//phosphoenolpyruvate carboxykinase activity;GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0017076//purine nucleotide binding;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0006090//pyruvate metabolic process;GO:0006094//gluconeogenesis;GO:0006107//oxaloacetate metabolic process;GO:0006116//NADH oxidation;GO:0016310//phosphorylation;GO:0019543//propionate catabolic process;GO:0032024//positive regulation of insulin secretion;GO:0032496//response to lipopolysaccharide;GO:0032869//cellular response to insulin stimulus;GO:0033993//response to lipid;GO:0042594//response to starvation;GO:0046327//glycerol biosynthetic process from pyruvate;GO:0070365//hepatocyte differentiation;GO:0071333//cellular response to glucose stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0071548//response to dexamethasone;GO:0071549//cellular response to dexamethasone stimulus	--
ENSG00000100890	12.52	13.148	12.06	9.232	11.492	12.396	585.49	529.11	392.7	289.17	400.24	382.18	PRORP	protein only RNase P catalytic subunit [Source:HGNC Symbol;Acc:HGNC:19958]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030678//mitochondrial ribonuclease P complex;GO:0043229//intracellular organelle	GO:0004518//nuclease activity;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0001682//tRNA 5'-leader removal;GO:0008033//tRNA processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0097745//mitochondrial tRNA 5'-end processing"	--
ENSG00000100897	30.411	34.701	41.213	40.393	40.585	39.589	1710.71	1909.87	1395	1612.95	1801.96	1456.85	DCAF11	DDB1 and CUL4 associated factor 11 [Source:HGNC Symbol;Acc:HGNC:20258]	-	-	-	-	GO:0005654//nucleoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000100902	39.15	38.404	40.15	34.963	31.98	40.382	822.62	810.8	624.16	539.55	571.35	619.03	PSMA6	proteasome 20S subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:9535]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02730;K02730;K02730;K02730;K02730;K02730;K02730;K02730	"GO:0000502//proteasome complex;GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0005844//polysome;GO:0016363//nuclear matrix;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0070062//extracellular exosome"	GO:0003723//RNA binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0035639//purine ribonucleoside triphosphate binding;GO:0051059//NF-kappaB binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050727//regulation of inflammatory response;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000100906	14.454	16.771	18.371	13.171	14.516	14.695	467	545	438	315	396	345	NFKBIA	NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cell growth and death;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: specific types;Immune system;Cancer: overview;Immune system;Cancer: specific types;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune system;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05220//Chronic myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis	K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734;K04734	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0033256//I-kappaB/NF-kappaB complex	GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008139//nuclear localization sequence binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0051059//NF-kappaB binding	"GO:0006606//protein import into nucleus;GO:0006915//apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0010468//regulation of gene expression;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010875//positive regulation of cholesterol efflux;GO:0010888//negative regulation of lipid storage;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032495//response to muramyl dipeptide;GO:0032496//response to lipopolysaccharide;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035994//response to muscle stretch;GO:0042127//regulation of cell population proliferation;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043330//response to exogenous dsRNA;GO:0043392//negative regulation of DNA binding;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050729//positive regulation of inflammatory response;GO:0070417//cellular response to cold;GO:0070427//nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:1901222//regulation of NIK/NF-kappaB signaling"	--
ENSG00000100908	9.541	10.504	14.377	14.693	14.096	13.251	171	193	194	197	217	176	EMC9	ER membrane protein complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:20273]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000100911	28.682	53.525	28.291	31.236	41.683	30.756	495	518	358	399	409	388	PSME2	proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569]	Organismal Systems;Genetic Information Processing	"Immune system;Folding, sorting and degradation"	ko04612//Antigen processing and presentation;ko03050//Proteasome	K06697;K06697	GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0061133//endopeptidase activator activity	GO:0010950//positive regulation of endopeptidase activity;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0061136//regulation of proteasomal protein catabolic process;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000100916	4.7	4.382	4.58	4.196	3.83	4.221	249	229	185	170	177	168	BRMS1L	BRMS1 like transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:20512]	-	-	-	-	GO:0005634//nucleus;GO:0016580//Sin3 complex;GO:0070822//Sin3-type complex	GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0040008//regulation of growth;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance	--
ENSG00000100918	58.77	63.387	80.081	93.38	83.961	97.991	2701	2915	2809	3243	3353	3352	REC8	REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K13054	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005694//chromosome;GO:0008278//cohesin complex;GO:0030893//meiotic cohesin complex;GO:0034990//nuclear mitotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex"	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0001556//oocyte maturation;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009566//fertilization;GO:0051177//meiotic sister chromatid cohesion;GO:0051321//meiotic cell cycle;GO:0072520//seminiferous tubule development;GO:1990414//replication-born double-strand break repair via sister chromatid exchange	--
ENSG00000100926	64.136	72.092	76.512	73.127	74.554	77.619	2596.51	3006.25	2349.33	2292.89	2659.64	2387	TM9SF1	transmembrane 9 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11864]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0006914//autophagy;GO:0072657//protein localization to membrane	--
ENSG00000100934	44.81	42.049	41.605	34.049	37.068	39.816	3538	3369	2447	2010	2416	2297	SEC23A	"SEC23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14006	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030127//COPII vesicle coat;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070971//endoplasmic reticulum exit site	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:0072659//protein localization to plasma membrane;GO:0090110//COPII-coated vesicle cargo loading;GO:0090114//COPII-coated vesicle budding	--
ENSG00000100938	46.552	48.529	46.455	45.992	46.153	43.7	1506	1536	1157	1068	1255	1057	GMPR2	guanosine monophosphate reductase 2 [Source:HGNC Symbol;Acc:HGNC:4377]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00364;K00364	GO:0005829//cytosol;GO:1902560//GMP reductase complex	GO:0003824//catalytic activity;GO:0003920//GMP reductase activity;GO:0003938//IMP dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006144//purine nucleobase metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0046037//GMP metabolic process	--
ENSG00000100941	20.36	17.719	16.089	12.942	16.804	17.471	1372	1201	824	678	958	861	PNN	"pinin, desmosome associated protein [Source:HGNC Symbol;Acc:HGNC:9162]"	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K13114;K13114	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030057//desmosome;GO:0035145//exon-exon junction complex;GO:0071013//catalytic step 2 spliceosome	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007155//cell adhesion;GO:0008380//RNA splicing"	--
ENSG00000100949	8.016	8.198	9.392	10.565	11.582	9.115	334	344	292	328	418	280	RABGGTA	Rab geranylgeranyltransferase subunit alpha [Source:HGNC Symbol;Acc:HGNC:9795]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005968//Rab-protein geranylgeranyltransferase complex	GO:0004659//prenyltransferase activity;GO:0004663//Rab geranylgeranyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding	GO:0006464//cellular protein modification process;GO:0007601//visual perception;GO:0018342//protein prenylation;GO:0018344//protein geranylgeranylation	--
ENSG00000100968	13.455	15.503	15.669	10.862	14.486	16.54	829	839	692	498	697	660	NFATC4	nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Signal transduction;Signal transduction;Infectious disease: viral;Cell growth and death;Endocrine system;Immune system	ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04625//C-type lectin receptor signaling pathway	K17334;K17334;K17334;K17334;K17334;K17334;K17334;K17334;K17334;K17334;K17334	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001569//branching involved in blood vessel morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007507//heart development;GO:0007616//long-term memory;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033173//calcineurin-NFAT signaling cascade;GO:0034644//cellular response to UV;GO:0035562//negative regulation of chromatin binding;GO:0043065//positive regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045333//cellular respiration;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0050774//negative regulation of dendrite morphogenesis;GO:0051145//smooth muscle cell differentiation;GO:0055001//muscle cell development;GO:0060291//long-term synaptic potentiation;GO:0071285//cellular response to lithium ion;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:2000297//negative regulation of synapse maturation;GO:2001235//positive regulation of apoptotic signaling pathway"	RHD
ENSG00000100979	385.127	395.185	440.261	469.122	438.706	402.228	14950.65	15418.58	12624	13483.46	14370.39	11344.12	PLTP	phospholipid transfer protein [Source:HGNC Symbol;Acc:HGNC:9093]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism	K08761;K08761	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0034364//high-density lipoprotein particle	GO:0005515//protein binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transfer activity;GO:0019992//diacylglycerol binding;GO:0030169//low-density lipoprotein particle binding;GO:0031210//phosphatidylcholine binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0070300//phosphatidic acid binding;GO:0097001//ceramide binding;GO:0120014//phospholipid transfer activity;GO:0120017//ceramide transfer activity;GO:0120019//phosphatidylcholine transfer activity;GO:0120020//cholesterol transfer activity;GO:0140337//diacylglyceride transfer activity;GO:0140338//sphingomyelin transfer activity;GO:0140339//phosphatidylglycerol transfer activity;GO:0140340//cerebroside transfer activity;GO:1901611//phosphatidylglycerol binding;GO:1904121//phosphatidylethanolamine transfer activity;GO:1990050//phosphatidic acid transfer activity	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0010189//vitamin E biosynthetic process;GO:0010875//positive regulation of cholesterol efflux;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0030317//flagellated sperm motility;GO:0034375//high-density lipoprotein particle remodeling;GO:0035627//ceramide transport;GO:0046836//glycolipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000100982	15.231	15.486	17.108	15.781	17.311	16.731	845	864	697	652	802	679	PCIF1	phosphorylated CTD interacting factor 1 [Source:HGNC Symbol;Acc:HGNC:16200]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016422//mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity;GO:0016740//transferase activity;GO:0099122//RNA polymerase II C-terminal domain binding;GO:1904047//S-adenosyl-L-methionine binding;GO:1990269//RNA polymerase II C-terminal domain phosphoserine binding	GO:0017148//negative regulation of translation;GO:0032259//methylation;GO:0045727//positive regulation of translation;GO:0080009//mRNA methylation	--
ENSG00000100983	22.88	21.139	22.087	25.212	21.895	23.28	878	840	644	699	723	667	GSS	glutathione synthetase [Source:HGNC Symbol;Acc:HGNC:4624]	Metabolism;Metabolism;Metabolism;Cellular Processes	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism;Cell growth and death	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00270//Cysteine and methionine metabolism;ko04216//Ferroptosis	K21456;K21456;K21456;K21456	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004363//glutathione synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding;GO:0046872//metal ion binding	GO:0006520//cellular amino acid metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006979//response to oxidative stress;GO:0007399//nervous system development;GO:0046686//response to cadmium ion	--
ENSG00000100985	0	0	0	0	0.024	0	0	0	0	0	1	0	MMP9	matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Signal transduction;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko05161//Hepatitis B;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04668//TNF signaling pathway;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04657//IL-17 signaling pathway;ko05219//Bladder cancer	K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403;K01403	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001934//positive regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0007566//embryo implantation;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030225//macrophage differentiation;GO:0030335//positive regulation of cell migration;GO:0030574//collagen catabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0035987//endodermal cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0050900//leukocyte migration;GO:0051549//positive regulation of keratinocyte migration;GO:0071276//cellular response to cadmium ion;GO:0071492//cellular response to UV-A;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0150077//regulation of neuroinflammatory response;GO:1900122//positive regulation of receptor binding;GO:1904645//response to amyloid-beta;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000697//negative regulation of epithelial cell differentiation involved in kidney development;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001258//negative regulation of cation channel activity;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000100987	0	0	0	0	0	0	0	0	0	0	0	0	VSX1	visual system homeobox 1 [Source:HGNC Symbol;Acc:HGNC:12723]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0042551//neuron maturation;GO:0048666//neuron development;GO:0050896//response to stimulus;GO:0060040//retinal bipolar neuron differentiation"	Homeobox
ENSG00000100991	35.843	36.874	36.814	36.47	36.971	34.609	2347	2427	1781	1769	2045	1649	TRPC4AP	transient receptor potential cation channel subfamily C member 4 associated protein [Source:HGNC Symbol;Acc:HGNC:16181]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0048820//hair follicle maturation;GO:0070588//calcium ion transmembrane transport;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000100994	27.608	30.03	30.894	31.732	29.447	28.816	2357	2577	1948	1904	2124	1790	PYGB	glycogen phosphorylase B [Source:HGNC Symbol;Acc:HGNC:9723]	Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cell growth and death;Endocrine system;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04217//Necroptosis;ko04910//Insulin signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00500//Starch and sucrose metabolism	K00688;K00688;K00688;K00688;K00688;K00688	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004645//1,4-alpha-oligoglucan phosphorylase activity;GO:0005515//protein binding;GO:0008184//glycogen phosphorylase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity"	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0008152//metabolic process	--
ENSG00000100997	33.298	35.225	37.455	45.131	44.926	38.477	1223	1333	1027	1212	1258	1030	ABHD12	"abhydrolase domain containing 12, lysophospholipase [Source:HGNC Symbol;Acc:HGNC:15868]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032281//AMPA glutamate receptor complex;GO:0032839//dendrite cytoplasm	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity	GO:0002084//protein depalmitoylation;GO:0006629//lipid metabolic process;GO:0006660//phosphatidylserine catabolic process;GO:0007628//adult walking behavior;GO:0009395//phospholipid catabolic process;GO:0010996//response to auditory stimulus;GO:0019369//arachidonic acid metabolic process;GO:0046464//acylglycerol catabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0050727//regulation of inflammatory response;GO:0052651//monoacylglycerol catabolic process	--
ENSG00000101000	2.073	2.738	1.597	2.268	2.453	2.014	58	77	33	47	58	41	PROCR	protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K06557	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0050819//negative regulation of coagulation	--
ENSG00000101003	1.322	1.362	1.325	1.594	0.896	2.026	72	93	65	71	49	55	GINS1	GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980]	-	-	-	-	GO:0000811//GINS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0071162//CMG complex	-	GO:0001833//inner cell mass cell proliferation;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:1900264//positive regulation of DNA-directed DNA polymerase activity;GO:1902983//DNA strand elongation involved in mitotic DNA replication;GO:1903934//positive regulation of DNA primase activity	--
ENSG00000101004	4.12	4.001	3.78	4.312	3.682	4.591	418	397	277	316	313	321	NINL	ninein like [Source:HGNC Symbol;Acc:HGNC:29163]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0034454//microtubule anchoring at centrosome	--
ENSG00000101017	2	2.101	1.921	1.606	1.536	2.026	58	71	38	41	43	46	CD40	CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Immune disease;Signal transduction;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Infectious disease: parasitic;Immune disease;Immune system;Immune disease;Infectious disease: parasitic	ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05322//Systemic lupus erythematosus;ko04064//NF-kappa B signaling pathway;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko04620//Toll-like receptor signaling pathway;ko05310//Asthma;ko05144//Malaria	K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160;K03160	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035631//CD40 receptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0038023//signaling receptor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0002637//regulation of immunoglobulin production;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0006954//inflammatory response;GO:0019724//B cell mediated immunity;GO:0023035//CD40 signaling pathway;GO:0030168//platelet activation;GO:0030890//positive regulation of B cell proliferation;GO:0032735//positive regulation of interleukin-12 production;GO:0034341//response to interferon-gamma;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0042100//B cell proliferation;GO:0042113//B cell activation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042832//defense response to protozoan;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0043491//protein kinase B signaling;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043547//positive regulation of GTPase activity;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050776//regulation of immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0065003//protein-containing complex assembly;GO:0071260//cellular response to mechanical stimulus;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090037//positive regulation of protein kinase C signaling;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000101019	12.778	13.221	14.025	11.149	11.727	12.561	530	582	416	349	457	425	UQCC1	ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:15891]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0034551//mitochondrial respiratory chain complex III assembly	--
ENSG00000101040	9.01	7.416	8.675	7.06	7.332	9.137	836	737	628	509	596	595	ZMYND8	zinc finger MYND-type containing 8 [Source:HGNC Symbol;Acc:HGNC:9397]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0070577//lysine-acetylated histone binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000101049	0.372	0.2	0.111	0.216	0.183	0.035	9	8	4	8	6	1	SGK2	serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04068//FoxO signaling pathway	K13303;K13303	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015459//potassium channel regulator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017080//sodium channel regulator activity;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032411//positive regulation of transporter activity;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation	--
ENSG00000101052	16.021	17.615	16	13.803	15.199	16.309	550	608	405	358	444	410	IFT52	intraflagellar transport 52 [Source:HGNC Symbol;Acc:HGNC:15901]	-	-	-	-	GO:0005813//centrosome;GO:0005814//centriole;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0044292//dendrite terminus;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:0097733//photoreceptor cell cilium	GO:0008022//protein C-terminus binding	GO:0001841//neural tube formation;GO:0001947//heart looping;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0009953//dorsal/ventral pattern formation;GO:0030030//cell projection organization;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0042733//embryonic digit morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060271//cilium assembly;GO:0070613//regulation of protein processing;GO:1905515//non-motile cilium assembly	--
ENSG00000101057	1.337	1.007	0.85	1.854	1.471	1.214	74	56	35	76	69	49	MYBL2	MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K21769	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031523//Myb complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0043525//positive regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090307//mitotic spindle assembly;GO:1990830//cellular response to leukemia inhibitory factor"	MYB
ENSG00000101074	0.51	0.653	0.099	0.787	0.345	0.351	14	18	2	16	8	7	R3HDML	R3H domain containing like [Source:HGNC Symbol;Acc:HGNC:16249]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity	--
ENSG00000101076	11.291	13.197	9.854	9.217	9.397	6.723	605	736	426	300	419	304	HNF4A	hepatocyte nuclear factor 4 alpha [Source:HGNC Symbol;Acc:HGNC:5024]	Environmental Information Processing;Human Diseases	Signal transduction;Endocrine and metabolic disease	ko04152//AMPK signaling pathway;ko04950//Maturity onset diabetes of the young	K07292;K07292	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005102//signaling receptor binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0003323//type B pancreatic cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006591//ornithine metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007548//sex differentiation;GO:0007596//blood coagulation;GO:0008285//negative regulation of cell population proliferation;GO:0009749//response to glucose;GO:0010470//regulation of gastrulation;GO:0019216//regulation of lipid metabolic process;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030522//intracellular receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0042752//regulation of circadian rhythm;GO:0043401//steroid hormone mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048856//anatomical structure development;GO:0050796//regulation of insulin secretion;GO:0055088//lipid homeostasis;GO:0055091//phospholipid homeostasis;GO:0060395//SMAD protein signal transduction;GO:0060398//regulation of growth hormone receptor signaling pathway;GO:0070328//triglyceride homeostasis;GO:0070365//hepatocyte differentiation"	RXR-like
ENSG00000101079	6.929	6.778	8.1	6.601	7.863	7.697	427	418	357	301	380	326	NDRG3	NDRG family member 3 [Source:HGNC Symbol;Acc:HGNC:14462]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth	--
ENSG00000101082	0	0	0	0.12	0.026	0	0	0	0	4	1	0	SLA2	Src like adaptor 2 [Source:HGNC Symbol;Acc:HGNC:17329]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035591//signaling adaptor activity;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0047485//protein N-terminus binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0009966//regulation of signal transduction;GO:0019724//B cell mediated immunity;GO:0042110//T cell activation;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0050776//regulation of immune response;GO:0050849//negative regulation of calcium-mediated signaling;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway	--
ENSG00000101084	35.654	36.065	40.811	46.847	36.651	40.256	791.97	807.28	672.02	770.67	690	649.59	RAB5IF	RAB5 interacting factor [Source:HGNC Symbol;Acc:HGNC:15870]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0097250//mitochondrial respirasome assembly	--
ENSG00000101096	0.392	0.357	0.441	0.164	0.235	0.31	47	56	47	19	28	35	NFATC2	nuclear factor of activated T cells 2 [Source:HGNC Symbol;Acc:HGNC:7776]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Infectious disease: viral;Cell growth and death;Endocrine system;Immune system;Development and regeneration;Immune system;Immune system;Immune system;Immune system;Cancer: overview;Signal transduction	ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04370//VEGF signaling pathway	K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332;K17332	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035976//transcription factor AP-1 complex;GO:1990904//ribonucleoprotein complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0014904//myotube cell development;GO:0016477//cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050853//B cell receptor signaling pathway;GO:1901741//positive regulation of myoblast fusion;GO:1905064//negative regulation of vascular associated smooth muscle cell differentiation"	RHD
ENSG00000101098	0.062	0.142	0.063	0.086	0.083	0.089	7	16	5.26	7.11	7.08	7.28	RIMS4	regulating synaptic membrane exocytosis 4 [Source:HGNC Symbol;Acc:HGNC:16183]	-	-	-	-	GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0097060//synaptic membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0042391//regulation of membrane potential;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000101104	1.294	0.536	0.95	1.774	1.287	1.015	41	22	25	43	32	26	PABPC1L	poly(A) binding protein cytoplasmic 1 like [Source:HGNC Symbol;Acc:HGNC:15797]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	"GO:0001556//oocyte maturation;GO:0006338//chromatin remodeling;GO:0006378//mRNA polyadenylation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0051647//nucleus localization"	--
ENSG00000101109	6.448	7.275	6.343	7.821	6.15	9.107	844	840	613	555	637	655	STK4	serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04068//FoxO signaling pathway;ko05223//Non-small cell lung cancer	K04411;K04411;K04411;K04411;K04411	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106310//protein serine kinase activity	"GO:0000902//cell morphogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001841//neural tube formation;GO:0001934//positive regulation of protein phosphorylation;GO:0003157//endocardium development;GO:0006468//protein phosphorylation;GO:0006606//protein import into nucleus;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030216//keratinocyte differentiation;GO:0032092//positive regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0045600//positive regulation of fat cell differentiation;GO:0046621//negative regulation of organ growth;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization;GO:0051262//protein tetramerization;GO:0060215//primitive hemopoiesis;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060800//regulation of cell differentiation involved in embryonic placenta development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097284//hepatocyte apoptotic process;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1904237//positive regulation of substrate-dependent cell migration, cell attachment to substrate"	--
ENSG00000101115	0	0.009	0.034	0	0.011	0.035	0	1	1	0	1	1	SALL4	spalt like transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:15924]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001833//inner cell mass cell proliferation;GO:0001843//neural tube closure;GO:0003281//ventricular septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0009888//tissue development;GO:0019827//stem cell population maintenance;GO:0021915//neural tube development;GO:0030326//embryonic limb morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000101126	29.895	26.673	26.676	21.584	22.505	21.451	3137	2843	2046	1683	2020	1664	ADNP	activity dependent neuroprotector homeobox [Source:HGNC Symbol;Acc:HGNC:15766]	-	-	-	-	GO:0000785//chromatin;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007614//short-term memory;GO:0009743//response to carbohydrate;GO:0010035//response to inorganic substance;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010835//regulation of protein ADP-ribosylation;GO:0010976//positive regulation of neuron projection development;GO:0019934//cGMP-mediated signaling;GO:0031668//cellular response to extracellular stimulus;GO:0032091//negative regulation of protein binding;GO:0032147//activation of protein kinase activity;GO:0033484//nitric oxide homeostasis;GO:0043524//negative regulation of neuron apoptotic process;GO:0044849//estrous cycle;GO:0045773//positive regulation of axon extension;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050805//negative regulation of synaptic transmission;GO:0051965//positive regulation of synapse assembly	Homeobox
ENSG00000101132	10.52	10.771	12.121	8.613	8.877	11.544	161	160	123	88	107	127	PFDN4	prefoldin subunit 4 [Source:HGNC Symbol;Acc:HGNC:8868]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016272//prefoldin complex	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0050821//protein stabilization;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000101134	6.827	7.03	5.415	7.405	5.169	6.572	274	288	163	214	178	185	DOK5	docking protein 5 [Source:HGNC Symbol;Acc:HGNC:16173]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030182//neuron differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0051386//regulation of neurotrophin TRK receptor signaling pathway	--
ENSG00000101138	14.932	13.919	14.807	13.421	13.88	13.165	599	558	439	392	443	398	CSTF1	cleavage stimulation factor subunit 1 [Source:HGNC Symbol;Acc:HGNC:2483]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14406	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005848//mRNA cleavage stimulating factor complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0031124//mRNA 3'-end processing	--
ENSG00000101144	249.446	276.391	257.663	207.499	223.045	202.505	19920	22062	15319	12150	15132	11852	BMP7	bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Development and regeneration;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04360//Axon guidance;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K16621;K16621;K16621;K16621	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031982//vesicle;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0070700//BMP receptor binding	"GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001654//eye development;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001707//mesoderm formation;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0001837//epithelial to mesenchymal transition;GO:0003272//endocardial cushion formation;GO:0003344//pericardium morphogenesis;GO:0007165//signal transduction;GO:0007389//pattern specification process;GO:0007411//axon guidance;GO:0007435//salivary gland morphogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010942//positive regulation of cell death;GO:0016358//dendrite development;GO:0021502//neural fold elevation formation;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0030902//hindbrain development;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032355//response to estradiol;GO:0033280//response to vitamin D;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034504//protein localization to nucleus;GO:0035239//tube morphogenesis;GO:0042325//regulation of phosphorylation;GO:0042326//negative regulation of phosphorylation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043065//positive regulation of apoptotic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0043434//response to peptide hormone;GO:0045597//positive regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045786//negative regulation of cell cycle;GO:0045839//negative regulation of mitotic nuclear division;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0048593//camera-type eye morphogenesis;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048738//cardiac muscle tissue development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048762//mesenchymal cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0050768//negative regulation of neurogenesis;GO:0051216//cartilage development;GO:0060037//pharyngeal system development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060411//cardiac septum morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060485//mesenchyme development;GO:0060548//negative regulation of cell death;GO:0060686//negative regulation of prostatic bud formation;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060710//chorio-allantoic fusion;GO:0061384//heart trabecula morphogenesis;GO:0070487//monocyte aggregation;GO:0071456//cellular response to hypoxia;GO:0071773//cellular response to BMP stimulus;GO:0072040//negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis;GO:0072125//negative regulation of glomerular mesangial cell proliferation;GO:0072133//metanephric mesenchyme morphogenesis;GO:0072134//nephrogenic mesenchyme morphogenesis;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0090336//positive regulation of brown fat cell differentiation;GO:1900006//positive regulation of dendrite development;GO:1900106//positive regulation of hyaluranon cable assembly;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1905069//allantois development;GO:1905312//positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:2000121//regulation of removal of superoxide radicals"	--
ENSG00000101146	9.048	13.302	12.35	14.006	9.287	11.722	391	371	327	324	324	290	RAE1	ribonucleic acid export 1 [Source:HGNC Symbol;Acc:HGNC:9828]	Human Diseases;Human Diseases;Genetic Information Processing	Neurodegenerative disease;Infectious disease: viral;Translation	ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K14298;K14298;K14298	GO:0000922//spindle pole;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0097431//mitotic spindle pole	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043130//ubiquitin binding	GO:0000972//transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0071407//cellular response to organic cyclic compound	--
ENSG00000101150	38.132	38.764	36.772	39.823	38.198	34.794	1807	1806	1289	1397	1533	1201	TPD52L2	TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0005975//carbohydrate metabolic process;GO:0042127//regulation of cell population proliferation	--
ENSG00000101152	23.864	23.756	26.159	25.367	26.553	26.258	2601	2603	2106	2049	2446	2083	DNAJC5	DnaJ heat shock protein family (Hsp40) member C5 [Source:HGNC Symbol;Acc:HGNC:16235]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09525	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0042470//melanosome;GO:0042584//chromaffin granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0098793//presynapse;GO:0098993//anchored component of synaptic vesicle membrane	GO:0005515//protein binding;GO:0043008//ATP-dependent protein binding	GO:0006887//exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0043524//negative regulation of neuron apoptotic process;GO:0045055//regulated exocytosis;GO:0061077//chaperone-mediated protein folding;GO:0098693//regulation of synaptic vesicle cycle	--
ENSG00000101158	27.795	27.708	30.662	30.052	30.119	28.112	1295.09	1295.86	1049.31	1035.39	1180.11	948.12	NELFCD	negative elongation factor complex member C/D [Source:HGNC Symbol;Acc:HGNC:15934]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0032021//NELF complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000101160	84.414	91.128	71.731	70.549	80.161	71.16	2647.91	2939.14	1706.69	1672.61	2162.89	1693.88	CTSZ	cathepsin Z [Source:HGNC Symbol;Acc:HGNC:2547]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K08568;K08568	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0035580//specific granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0004180//carboxypeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0002003//angiotensin maturation;GO:0006508//proteolysis;GO:0010757//negative regulation of plasminogen activation;GO:0032091//negative regulation of protein binding;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:1901214//regulation of neuron death	--
ENSG00000101161	37.927	38.063	43.661	42.636	42.138	35.751	2397	2418	2038	1996	2250	1644	PRPF6	pre-mRNA processing factor 6 [Source:HGNC Symbol;Acc:HGNC:15860]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12855	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0050681//androgen receptor binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000245//spliceosomal complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006403//RNA localization;GO:0008380//RNA splicing;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000101162	0.015	0.015	0.04	0.02	0.035	0.061	1.01	1.01	2.02	1.01	2.02	3.05	TUBB1	tubulin beta 1 class VI [Source:HGNC Symbol;Acc:HGNC:16257]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0051225//spindle assembly	--
ENSG00000101166	11.981	8.513	11.683	9.012	7.729	11.698	557	398	387	287	288	411	PRELID3B	PRELI domain containing 3B [Source:HGNC Symbol;Acc:HGNC:15892]	-	-	-	-	GO:0005758//mitochondrial intermembrane space	GO:1990050//phosphatidic acid transfer activity	GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000101180	0	0	0	0	0	0	0	0	0	0	0	0	HRH3	histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04151	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0098793//presynapse	GO:0004930//G protein-coupled receptor activity;GO:0004969//histamine receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0001505//regulation of neurotransmitter levels;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0014050//negative regulation of glutamate secretion;GO:0014061//regulation of norepinephrine secretion;GO:0014063//negative regulation of serotonin secretion;GO:0050890//cognition;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000101181	7.632	8.023	7.879	10.081	9.356	9.687	396	425	301	361	374	319	MTG2	mitochondrial ribosome associated GTPase 2 [Source:HGNC Symbol;Acc:HGNC:16239]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005761//mitochondrial ribosome;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0006417//regulation of translation;GO:0042254//ribosome biogenesis;GO:0044065//regulation of respiratory system process;GO:0070129//regulation of mitochondrial translation	--
ENSG00000101182	65.749	65.13	73.423	67.922	64.99	72.248	1307	1302	1076	1001	1091	1045	PSMA7	proteasome 20S subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:9536]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02731;K02731;K02731;K02731;K02731;K02731;K02731;K02731	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular exosome;GO:0098794//postsynapse"	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000101187	7.4	7.533	6.984	6.085	6.063	9.094	394	410	292	252	290	343	SLCO4A1	solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport	--
ENSG00000101188	0.152	0.162	0.095	0.079	0.041	0.08	13	14	6	5	3	5	NTSR1	neurotensin receptor 1 [Source:HGNC Symbol;Acc:HGNC:8039]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04211;K04211	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032280//symmetric synapse;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0044309//neuron spine;GO:0045121//membrane raft;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0016492//G protein-coupled neurotensin receptor activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding	GO:0001659//temperature homeostasis;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0003254//regulation of membrane depolarization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007612//learning;GO:0008344//adult locomotory behavior;GO:0010628//positive regulation of gene expression;GO:0014049//positive regulation of glutamate secretion;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0033993//response to lipid;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043576//regulation of respiratory gaseous exchange;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051930//regulation of sensory perception of pain;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0070779//D-aspartate import across plasma membrane;GO:0071545//inositol phosphate catabolic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:0098712//L-glutamate import across plasma membrane;GO:0098900//regulation of action potential;GO:2001259//positive regulation of cation channel activity	--
ENSG00000101189	5.115	4.113	5.1	3.808	4.728	5.177	292	236	215	161	228	215	MRGBP	MRG domain binding protein [Source:HGNC Symbol;Acc:HGNC:15866]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043189//H4/H2A histone acetyltransferase complex	GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000101190	7.424	7.536	6.645	7.032	6.896	8.479	399.09	409	265	280	315	333	TCFL5	transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646]	-	-	-	-	GO:0000785//chromatin;GO:0001673//male germ cell nucleus;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042127//regulation of cell population proliferation;GO:0045595//regulation of cell differentiation"	bHLH
ENSG00000101191	14.086	13.27	14.564	12.951	13.663	12.96	1757	1721	1337	1162	1387	1217	DIDO1	death inducer-obliterator 1 [Source:HGNC Symbol;Acc:HGNC:2680]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton	GO:0003723//RNA binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway"	--
ENSG00000101193	14.842	16.49	15.374	14.465	14.629	15.06	1345	1502	1029	971	1120	993	GID8	GID complex subunit 8 homolog [Source:HGNC Symbol;Acc:HGNC:15857]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0008284//positive regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000101194	0.112	0.055	0.176	0.025	0	0.075	6	4	7	1	0	4	SLC17A9	solute carrier family 17 member 9 [Source:HGNC Symbol;Acc:HGNC:16192]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0042584//chromaffin granule membrane	GO:0001409//guanine nucleotide transmembrane transporter activity;GO:0005347//ATP transmembrane transporter activity;GO:0005515//protein binding;GO:0015217//ADP transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006887//exocytosis;GO:0015866//ADP transport;GO:0015867//ATP transport;GO:0055085//transmembrane transport;GO:1903790//guanine nucleotide transmembrane transport;GO:1904669//ATP export	--
ENSG00000101197	2.454	3.038	2.876	3.012	2.992	3.723	67	84	54	61	69	72	BIRC7	baculoviral IAP repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:13702]	Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Cellular Processes	"Cancer: overview;Folding, sorting and degradation;Infectious disease: parasitic;Cancer: specific types;Cell growth and death"	ko05200//Pathways in cancer;ko04120//Ubiquitin mediated proteolysis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04215//Apoptosis - multiple species	K16061;K16061;K16061;K16061;K16061	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002088//lens development in camera-type eye;GO:0006915//apoptotic process;GO:0010466//negative regulation of peptidase activity;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046330//positive regulation of JNK cascade;GO:0051726//regulation of cell cycle;GO:0070247//regulation of natural killer cell apoptotic process	--
ENSG00000101198	4.179	6.401	4.602	8.046	6.542	4.71	118	182	96	169	156	97	NKAIN4	sodium/potassium transporting ATPase interacting 4 [Source:HGNC Symbol;Acc:HGNC:16191]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002028//regulation of sodium ion transport	--
ENSG00000101199	14.653	14.673	15.877	17.62	14.093	15.452	799	887	737	706	733	613	ARFGAP1	ADP ribosylation factor GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:15852]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12492	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0045202//synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030100//regulation of endocytosis;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000101200	0	0	0	0	0	0	0	0	0	0	0	0	AVP	arginine vasopressin [Source:HGNC Symbol;Acc:HGNC:894]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Circulatory system;Excretory system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04270//Vascular smooth muscle contraction;ko04962//Vasopressin-regulated water reabsorption	K05242;K05242;K05242;K05242	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0004672//protein kinase activity;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005185//neurohypophyseal hormone activity;GO:0005515//protein binding;GO:0031894//V1A vasopressin receptor binding;GO:0031895//V1B vasopressin receptor binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0002125//maternal aggressive behavior;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation;GO:0006833//water transport;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007621//negative regulation of female receptivity;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0014049//positive regulation of glutamate secretion;GO:0014070//response to organic cyclic compound;GO:0030307//positive regulation of cell growth;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0032849//positive regulation of cellular pH reduction;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033574//response to testosterone;GO:0035094//response to nicotine;GO:0035176//social behavior;GO:0035813//regulation of renal sodium excretion;GO:0042310//vasoconstriction;GO:0042538//hyperosmotic salinity response;GO:0042711//maternal behavior;GO:0043066//negative regulation of apoptotic process;GO:0043084//penile erection;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045471//response to ethanol;GO:0045907//positive regulation of vasoconstriction;GO:0046718//viral entry into host cell;GO:0050891//multicellular organismal water homeostasis;GO:0051970//negative regulation of transmission of nerve impulse;GO:0070371//ERK1 and ERK2 cascade;GO:0070528//protein kinase C signaling;GO:0090201//negative regulation of release of cytochrome c from mitochondria	--
ENSG00000101203	0.03	0.121	0.079	0.279	0.276	0.165	5	13	3	12	8	3	COL20A1	collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24357	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	GO:0030199//collagen fibril organization	--
ENSG00000101204	0.043	0.099	0.058	0.058	0.122	0.036	5	6	5	5	11	3	CHRNA4	cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Cancer: overview;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse;ko05033//Nicotine addiction	K04806;K04806;K04806;K04806	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding	"GO:0001508//action potential;GO:0001666//response to hypoxia;GO:0006281//DNA repair;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0014059//regulation of dopamine secretion;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0035095//behavioral response to nicotine;GO:0042113//B cell activation;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0050890//cognition;GO:0051899//membrane depolarization;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0060080//inhibitory postsynaptic potential"	--
ENSG00000101210	13.926	12.122	8.302	19.459	19.697	18.636	456	408	203	482	540	430	EEF1A2	eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:HGNC:3192]	Human Diseases;Genetic Information Processing;Human Diseases	Infectious disease: parasitic;Translation;Infectious disease: bacterial	ko05140//Leishmaniasis;ko03013//Nucleocytoplasmic transport;ko05134//Legionellosis	K03231;K03231;K03231	GO:0005737//cytoplasm;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0045202//synapse;GO:0098574//cytoplasmic side of lysosomal membrane	"GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008135//translation factor activity, RNA binding;GO:0019901//protein kinase binding"	GO:0006412//translation;GO:0006414//translational elongation;GO:0043065//positive regulation of apoptotic process;GO:0090218//positive regulation of lipid kinase activity;GO:1904714//regulation of chaperone-mediated autophagy	--
ENSG00000101213	0.06	0.097	0.082	0.044	0.058	0	3	6	3	2	3	0	PTK6	protein tyrosine kinase 6 [Source:HGNC Symbol;Acc:HGNC:9617]	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0038128//ERBB2 signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045087//innate immune response;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045787//positive regulation of cell cycle;GO:0045926//negative regulation of growth;GO:0046777//protein autophosphorylation;GO:0060575//intestinal epithelial cell differentiation;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0071300//cellular response to retinoic acid	--
ENSG00000101216	5.932	6.108	6.207	5.687	5.866	5.527	527	545	407	374	440	357	GMEB2	glucocorticoid modulatory element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4371]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	SAND
ENSG00000101220	9.434	8.888	9.906	10.761	12.56	10.532	245	232	190	207	272	199	C20orf27	chromosome 20 open reading frame 27 [Source:HGNC Symbol;Acc:HGNC:15873]	-	-	-	-	GO:0005575//cellular_component	GO:0008157//protein phosphatase 1 binding	GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000101222	1.587	2.004	2.644	0.824	0.614	0.797	52	66	64	20	17	19	SPEF1	sperm flagellar 1 [Source:HGNC Symbol;Acc:HGNC:15874]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097729//9+2 motile cilium;GO:1990716//axonemal central apparatus	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding	"GO:0001578//microtubule bundle formation;GO:0003341//cilium movement;GO:0007026//negative regulation of microtubule depolymerization;GO:0016477//cell migration;GO:0030030//cell projection organization;GO:0030032//lamellipodium assembly;GO:0046847//filopodium assembly;GO:0051493//regulation of cytoskeleton organization;GO:0060548//negative regulation of cell death;GO:1904158//axonemal central apparatus assembly;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000101224	16.292	15.05	15.133	13.417	14.73	19.265	1050	977	716	631	792	906	CDC25B	cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems	Signal transduction;Cancer: overview;Cell growth and death;Endocrine system	ko04010//MAPK signaling pathway;ko05206//MicroRNAs in cancer;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K05866;K05866;K05866;K05866	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0001556//oocyte maturation;GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0007144//female meiosis I;GO:0008284//positive regulation of cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0032467//positive regulation of cytokinesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0045931//positive regulation of mitotic cell cycle;GO:0051301//cell division;GO:0110032//positive regulation of G2/MI transition of meiotic cell cycle;GO:1902751//positive regulation of cell cycle G2/M phase transition	--
ENSG00000101230	0.078	0.155	0	0	0	0	5	10	0	0	0	0	ISM1	isthmin 1 [Source:HGNC Symbol;Acc:HGNC:16213]	-	-	-	-	GO:0005576//extracellular region	-	GO:0016525//negative regulation of angiogenesis	--
ENSG00000101236	3.377	3.937	2.481	1.958	3.158	2.581	381.02	408.21	239.49	123.78	202.04	161.75	RNF24	ring finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13779]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000101246	15.094	16.219	17.648	18.019	17.603	18.924	483	543	411	429	502	467	ARFRP1	ADP ribosylation factor related protein 1 [Source:HGNC Symbol;Acc:HGNC:662]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0007369//gastrulation;GO:0033365//protein localization to organelle;GO:0034067//protein localization to Golgi apparatus;GO:0042147//retrograde transport, endosome to Golgi;GO:0043001//Golgi to plasma membrane protein transport"	--
ENSG00000101247	2.507	2.258	2.544	2.393	2.539	3.131	95	99	80	72	82	80	NDUFAF5	NADH:ubiquinone oxidoreductase complex assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:15899]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18162	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity	GO:0030961//peptidyl-arginine hydroxylation;GO:0032259//methylation;GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000101251	0	0	0	0	0.161	0	0	0	0	0	2	0	SEL1L2	SEL1L2 adaptor subunit of ERAD E3 ligase [Source:HGNC Symbol;Acc:HGNC:15897]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14026	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0036503//ERAD pathway	--
ENSG00000101255	2.353	2.832	3.159	3.232	3.386	8.381	115	119	114	117	133	298	TRIB3	tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228]	Human Diseases	Endocrine and metabolic disease	ko04931//Insulin resistance	K19518	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003714//transcription corepressor activity;GO:0004672//protein kinase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0010506//regulation of autophagy;GO:0010827//regulation of glucose transmembrane transport;GO:0032092//positive regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0034976//response to endoplasmic reticulum stress;GO:0043405//regulation of MAP kinase activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"	--
ENSG00000101265	3.649	3.827	2.785	1.911	1.969	1.721	408	430	230	157	186	140	RASSF2	Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883]	Environmental Information Processing	Signal transduction	ko04392//Hippo signaling pathway - multiple species	K09851	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex"	GO:0004672//protein kinase activity;GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0031954//positive regulation of protein autophosphorylation;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0038168//epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0045667//regulation of osteoblast differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0046849//bone remodeling;GO:0048872//homeostasis of number of cells;GO:0050821//protein stabilization;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000101266	55.699	54.935	55.388	51.499	43.557	58.062	2653	2687	1942.03	1823	2017	2043	CSNK2A1	casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Translation;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05020//Prion disease;ko04064//NF-kappa B signaling pathway;ko04310//Wnt signaling pathway;ko05162//Measles;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko03008//Ribosome biogenesis in eukaryotes;ko04137//Mitophagy - animal;ko04520//Adherens junction	K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005956//protein kinase CK2 complex;GO:0016580//Sin3 complex;GO:0016581//NuRD complex;GO:0031519//PcG protein complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0047485//protein N-terminus binding;GO:0051879//Hsp90 protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030307//positive regulation of cell growth;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045732//positive regulation of protein catabolic process;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle;GO:0061077//chaperone-mediated protein folding;GO:1905818//regulation of chromosome separation;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000101276	0	0	0	0	0	0	0	0	0	0	0	0	SLC52A3	solute carrier family 52 member 3 [Source:HGNC Symbol;Acc:HGNC:16187]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14620	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0032217//riboflavin transmembrane transporter activity	GO:0006771//riboflavin metabolic process;GO:0007605//sensory perception of sound;GO:0032218//riboflavin transport;GO:0034605//cellular response to heat	--
ENSG00000101280	0.021	0	0	0.014	0.012	0.014	2	0	0	1	1	1	ANGPT4	angiopoietin 4 [Source:HGNC Symbol;Acc:HGNC:487]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04066//HIF-1 signaling pathway	K05467;K05467;K05467;K05467;K05467	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007219//Notch signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071456//cellular response to hypoxia	--
ENSG00000101282	0.017	0	0	0	0.237	0.263	1	0	0	0	3	4	RSPO4	R-spondin 4 [Source:HGNC Symbol;Acc:HGNC:16175]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K23099	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0008201//heparin binding	GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035878//nail development;GO:0050896//response to stimulus	--
ENSG00000101290	17.884	19.22	18.997	17.085	18.631	20.125	2511	2527	1962	1622	2204	2025	CDS2	CDP-diacylglycerol synthase 2 [Source:HGNC Symbol;Acc:HGNC:1801]	Metabolism;Metabolism;Environmental Information Processing	Global and overview maps;Lipid metabolism;Signal transduction	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system	K00981;K00981;K00981	GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004605//phosphatidate cytidylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016779//nucleotidyltransferase activity"	GO:0006629//lipid metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0140042//lipid droplet formation	--
ENSG00000101292	0	0	0	0	0	0	0	0	0	0	0	0	PROKR2	prokineticin receptor 2 [Source:HGNC Symbol;Acc:HGNC:15836]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007623//circadian rhythm	--
ENSG00000101294	180.351	183.113	190.097	205.235	197.04	195.404	6109	6228	4729	5079	5612	4802	HM13	histocompatibility minor 13 [Source:HGNC Symbol;Acc:HGNC:16435]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0042803//protein homodimerization activity"	"GO:0001701//in utero embryonic development;GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0033619//membrane protein proteolysis;GO:0061960//regulation of heme oxygenase activity;GO:1904211//membrane protein proteolysis involved in retrograde protein transport, ER to cytosol"	--
ENSG00000101298	1.503	1.24	1.307	1.497	1.752	1.888	138	124	100	112	135	130	SNPH	syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding;GO:0017075//syntaxin-1 binding	GO:0007269//neurotransmitter secretion;GO:0016081//synaptic vesicle docking;GO:0030182//neuron differentiation	--
ENSG00000101306	0.017	0.034	0	0.023	0.02	0.047	1	2	0	1	1	2	MYLK2	myosin light chain kinase 2 [Source:HGNC Symbol;Acc:HGNC:16243]	Environmental Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cellular community - eukaryotes;Signal transduction;Endocrine system;Signal transduction;Circulatory system;Immune system;Digestive system	ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04971//Gastric acid secretion	K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030017//sarcomere;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004687//myosin light chain kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0032027//myosin light chain binding	GO:0006468//protein phosphorylation;GO:0006941//striated muscle contraction;GO:0007274//neuromuscular synaptic transmission;GO:0010628//positive regulation of gene expression;GO:0014816//skeletal muscle satellite cell differentiation;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032971//regulation of muscle filament sliding;GO:0035914//skeletal muscle cell differentiation;GO:0046777//protein autophosphorylation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000101307	0.119	0.088	0	0	0.216	0	4.19	3.12	0	0	6.13	0	SIRPB1	signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K06551	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0050766//positive regulation of phagocytosis;GO:0050870//positive regulation of T cell activation	--
ENSG00000101310	28.944	30.949	31.137	27.71	27.74	32.381	1625	1622	1308	1174	1338	1293	SEC23B	"SEC23 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10702]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14006	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070971//endoplasmic reticulum exit site	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:0090110//COPII-coated vesicle cargo loading;GO:0090114//COPII-coated vesicle budding	--
ENSG00000101311	0.23	0.406	0.183	0.182	0.159	0.353	20	31	13	13	9	19	FERMT1	FERM domain containing kindlin 1 [Source:HGNC Symbol;Acc:HGNC:15889]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0071944//cell periphery	GO:0005178//integrin binding;GO:0051015//actin filament binding	"GO:0001954//positive regulation of cell-matrix adhesion;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0010629//negative regulation of gene expression;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033625//positive regulation of integrin activation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0042308//negative regulation of protein import into nucleus;GO:0043616//keratinocyte proliferation;GO:0051546//keratinocyte migration;GO:0051886//negative regulation of timing of anagen;GO:0071636//positive regulation of transforming growth factor beta production;GO:0071711//basement membrane organization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090162//establishment of epithelial cell polarity;GO:1903691//positive regulation of wound healing, spreading of epidermal cells;GO:2000647//negative regulation of stem cell proliferation"	--
ENSG00000101323	0	0	0	0	0	0	0	0	0	0	0	0	HAO1	hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809]	Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Global and overview maps;Transport and catabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04146//Peroxisome;ko00630//Glyoxylate and dicarboxylate metabolism	K11517;K11517;K11517;K11517	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0003973//(S)-2-hydroxy-acid oxidase activity;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0047969//glyoxylate oxidase activity	GO:0001561//fatty acid alpha-oxidation;GO:0006979//response to oxidative stress;GO:0046296//glycolate catabolic process	--
ENSG00000101327	0	0	0	0	0	0	0	0	0	0	0	0	PDYN	prodynorphin [Source:HGNC Symbol;Acc:HGNC:8820]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Signaling molecules and interaction;Substance dependence;Neurodegenerative disease;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko04080//Neuroactive ligand-receptor interaction;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K15840;K15840;K15840;K15840;K15840;K15840	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse	GO:0001515//opioid peptide activity;GO:0031628//opioid receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007600//sensory perception	--
ENSG00000101331	0.074	0.074	0.026	0.026	0	0.053	4	4	1	1	0	2	CCM2L	CCM2 like scaffold protein [Source:HGNC Symbol;Acc:HGNC:16153]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0003007//heart morphogenesis;GO:0008150//biological_process	--
ENSG00000101333	7.361	5.317	3.854	3.046	3.61	3.716	835	558	327	189	350	306	PLCB4	phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Immune system;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Immune system;Immune system;Infectious disease: parasitic;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Sensory system;Digestive system;Endocrine system;Carbohydrate metabolism;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system;Excretory system;Digestive system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko00562//Inositol phosphate metabolism;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption"	K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858	GO:0005829//cytosol	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000101335	161.527	169.226	167.489	198.712	178.673	188.736	5217	5446	4132	4796	4890	4426	MYL9	myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cell motility;Cellular community - eukaryotes;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Endocrine system;Circulatory system;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04360//Axon guidance;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04670//Leukocyte transendothelial migration	K12755;K12755;K12755;K12755;K12755;K12755;K12755;K12755;K12755;K12755;K12755	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005859//muscle myosin complex;GO:0005938//cell cortex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030016//myofibril;GO:0030018//Z disc	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0032036//myosin heavy chain binding;GO:0046872//metal ion binding	GO:0006937//regulation of muscle contraction;GO:0030239//myofibril assembly;GO:0070527//platelet aggregation	--
ENSG00000101336	0	0	0	0	0	0	0	0	0	0	0	0	HCK	"HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840]"	Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Immune system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04666//Fc gamma R-mediated phagocytosis	K08893;K08893;K08893	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030133//transport vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0002376//immune system process;GO:0002522//leukocyte migration involved in immune response;GO:0002758//innate immune response-activating signal transduction;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006468//protein phosphorylation;GO:0006887//exocytosis;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007498//mesoderm development;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030838//positive regulation of actin filament polymerization;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043066//negative regulation of apoptotic process;GO:0043299//leukocyte degranulation;GO:0045087//innate immune response;GO:0045728//respiratory burst after phagocytosis;GO:0046777//protein autophosphorylation;GO:0050727//regulation of inflammatory response;GO:0050764//regulation of phagocytosis;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0071801//regulation of podosome assembly;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000101337	35.751	38.067	38.862	37.859	41.229	42.887	2781	2978	2250	2193	2723	2396	TM9SF4	transmembrane 9 superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:30797]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001666//response to hypoxia;GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0051453//regulation of intracellular pH;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0072657//protein localization to membrane;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000101342	1.046	0.527	0.44	0.706	0.694	0.412	35.7	22.8	12.2	19	20	9	TLDC2	TBC/LysM-associated domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16112]	-	-	-	-	GO:0005634//nucleus	-	GO:0006979//response to oxidative stress	--
ENSG00000101343	8.574	6.941	6.443	5.187	5.232	5.71	714	581	400	320	369	346	CRNKL1	crooked neck pre-mRNA splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:15762]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12869	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071014//post-mRNA release spliceosomal complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000101346	15.787	16.674	16.301	17.125	16.548	15.463	1707	1808	1305	1375	1503	1215	POFUT1	protein O-fucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:14988]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K03691	GO:0005783//endoplasmic reticulum;GO:0016020//membrane	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046922//peptide-O-fucosyltransferase activity	"GO:0001525//angiogenesis;GO:0001756//somitogenesis;GO:0005975//carbohydrate metabolic process;GO:0006004//fucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008593//regulation of Notch signaling pathway;GO:0016266//O-glycan processing;GO:0036066//protein O-linked fucosylation"	--
ENSG00000101347	6.246	4.808	5.704	4.486	4.092	4.338	506.3	416.2	353.8	257	326	288	SAMHD1	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K22544	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005886//plasma membrane;GO:0035861//site of double-strand break;GO:0097197//tetraspanin-enriched microdomain	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0008832//dGTPase activity;GO:0016787//hydrolase activity;GO:0016793//triphosphoric monoester hydrolase activity;GO:0032567//dGTP binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106375//deoxynucleoside triphosphate hydrolase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0002376//immune system process;GO:0006203//dGTP catabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0009264//deoxyribonucleotide catabolic process;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0046061//dATP catabolic process;GO:0051289//protein homotetramerization;GO:0051607//defense response to virus;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0110025//DNA strand resection involved in replication fork processing	--
ENSG00000101349	0.69	0.457	0.649	0.358	0.544	0.735	66	45	47	26	44	53	PAK5	p21 (RAC1) activated kinase 5 [Source:HGNC Symbol;Acc:HGNC:15916]	Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Cell motility;Infectious disease: viral;Cellular community - eukaryotes;Development and regeneration;Immune system;Signal transduction;Cancer: specific types	ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04510//Focal adhesion;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma	K05736;K05736;K05736;K05736;K05736;K05736;K05736;K05736	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007612//learning;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000101350	20.141	18.979	17.685	15.303	15.6	13.683	2555	2420	1657	1438	1672	1263	KIF3B	kinesin family member 3B [Source:HGNC Symbol;Acc:HGNC:6320]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005873//plus-end kinesin complex;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016939//kinesin II complex;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030496//midbody;GO:0032839//dendrite cytoplasm;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0097542//ciliary tip;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0031267//small GTPase binding;GO:0120170//intraciliary transport particle B binding	GO:0007018//microtubule-based movement;GO:0007052//mitotic spindle organization;GO:0007100//mitotic centrosome separation;GO:0007368//determination of left/right symmetry;GO:0008089//anterograde axonal transport;GO:0016192//vesicle-mediated transport;GO:0032467//positive regulation of cytokinesis;GO:0036372//opsin transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0090307//mitotic spindle assembly;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex	--
ENSG00000101353	0.653	0.696	0.293	0.614	0.883	0.871	23	25	10	21	27	19	MROH8	maestro heat like repeat family member 8 [Source:HGNC Symbol;Acc:HGNC:16125]	-	-	-	-	-	-	-	--
ENSG00000101361	26.175	29.135	26.213	20.722	22.891	20.083	1032	1152	763	601	761	576	NOP56	NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05017//Spinocerebellar ataxia;ko03008//Ribosome biogenesis in eukaryotes	K14564;K14564	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome;GO:0070761//pre-snoRNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0045296//cadherin binding;GO:1990226//histone methyltransferase binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000101363	32.12	36.39	38.643	41.487	33.735	36.179	884	1005	789	824	790	724	MANBAL	mannosidase beta like [Source:HGNC Symbol;Acc:HGNC:15799]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000101365	23.457	24.503	26.677	29.325	29.078	31.377	707	752	609	633	731	699	IDH3B	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:5385]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K00030;K00030;K00030;K00030;K00030	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005962//mitochondrial isocitrate dehydrogenase complex (NAD+)	"GO:0000287//magnesium ion binding;GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0051287//NAD binding"	GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006734//NADH metabolic process;GO:0022900//electron transport chain	--
ENSG00000101367	55.456	53.694	56.411	56.627	53.278	56.795	2947	2868	2214	2229	2392	2196	MAPRE1	microtubule associated protein RP/EB family member 1 [Source:HGNC Symbol;Acc:HGNC:6890]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0030981//cortical microtubule cytoskeleton;GO:0031253//cell projection membrane;GO:0035371//microtubule plus-end;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0051233//spindle midzone;GO:0097431//mitotic spindle pole;GO:1905721//mitotic spindle astral microtubule end	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051010//microtubule plus-end binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001578//microtubule bundle formation;GO:0007049//cell cycle;GO:0008104//protein localization;GO:0016477//cell migration;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031115//negative regulation of microtubule polymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0035372//protein localization to microtubule;GO:0046785//microtubule polymerization;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0071539//protein localization to centrosome;GO:1902888//protein localization to astral microtubule;GO:1903033//positive regulation of microtubule plus-end binding;GO:1904825//protein localization to microtubule plus-end;GO:1905515//non-motile cilium assembly	--
ENSG00000101384	3.23	3.081	2.648	1.875	1.47	1.779	398	376	241	113	153	117	JAG1	jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Signal transduction;Signal transduction;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko04371//Apelin signaling pathway;ko04668//TNF signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06052;K06052;K06052;K06052;K06052;K06052;K06052;K06052;K06052	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0045177//apical part of cell	GO:0005112//Notch binding;GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008083//growth factor activity	GO:0001525//angiogenesis;GO:0001709//cell fate determination;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001974//blood vessel remodeling;GO:0002011//morphogenesis of an epithelial sheet;GO:0002456//T cell mediated immunity;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0007154//cell communication;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development;GO:0007399//nervous system development;GO:0009887//animal organ morphogenesis;GO:0022408//negative regulation of cell-cell adhesion;GO:0030097//hemopoiesis;GO:0030216//keratinocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0032495//response to muramyl dipeptide;GO:0035909//aorta morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042491//inner ear auditory receptor cell differentiation;GO:0043010//camera-type eye development;GO:0045445//myoblast differentiation;GO:0045446//endothelial cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:0060411//cardiac septum morphogenesis;GO:0061073//ciliary body morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0061444//endocardial cushion cell development;GO:0062043//positive regulation of cardiac epithelial to mesenchymal transition;GO:0072006//nephron development;GO:0072015//glomerular visceral epithelial cell development;GO:0072017//distal tubule development;GO:0072070//loop of Henle development;GO:0097150//neuronal stem cell population maintenance;GO:2000737//negative regulation of stem cell differentiation	--
ENSG00000101391	6.638	7.126	7.72	8.151	7.22	8.675	286	309	246	260	255	273	CDK5RAP1	CDK5 regulatory subunit associated protein 1 [Source:HGNC Symbol;Acc:HGNC:15880]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0035596//methylthiotransferase activity;GO:0035597//N6-isopentenyladenosine methylthiotransferase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006400//tRNA modification;GO:0007420//brain development;GO:0008033//tRNA processing;GO:0035600//tRNA methylthiolation;GO:0045664//regulation of neuron differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045903//positive regulation of translational fidelity;GO:0070131//positive regulation of mitochondrial translation;GO:0070900//mitochondrial tRNA modification	--
ENSG00000101400	72.873	74.388	76.467	90.432	83.39	88.557	3342	3429	2590	3072	3231	2955	SNTA1	syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016013//syntrophin complex;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0017080//sodium channel regulator activity;GO:0030165//PDZ domain binding;GO:0044325//transmembrane transporter binding;GO:0050998//nitric-oxide synthase binding;GO:0051117//ATPase binding	GO:0002027//regulation of heart rate;GO:0003117//regulation of vasoconstriction by circulating norepinephrine;GO:0006936//muscle contraction;GO:0007528//neuromuscular junction development;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1902305//regulation of sodium ion transmembrane transport	--
ENSG00000101405	0	0	0	0	0	0	0	0	0	0	0	0	OXT	oxytocin/neurophysin I prepropeptide [Source:HGNC Symbol;Acc:HGNC:8528]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04921//Oxytocin signaling pathway	K05243;K05243;K05243	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030141//secretory granule;GO:0043195//terminal bouton	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005185//neurohypophyseal hormone activity;GO:0005515//protein binding;GO:0031855//oxytocin receptor binding	GO:0001975//response to amphetamine;GO:0002027//regulation of heart rate;GO:0002125//maternal aggressive behavior;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007613//memory;GO:0007625//grooming behavior;GO:0009744//response to sucrose;GO:0010701//positive regulation of norepinephrine secretion;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0030431//sleep;GO:0032094//response to food;GO:0032308//positive regulation of prostaglandin secretion;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032570//response to progesterone;GO:0034695//response to prostaglandin E;GO:0035176//social behavior;GO:0035811//negative regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0042220//response to cocaine;GO:0042538//hyperosmotic salinity response;GO:0042711//maternal behavior;GO:0042713//sperm ejaculation;GO:0042755//eating behavior;GO:0042756//drinking behavior;GO:0043434//response to peptide hormone;GO:0044058//regulation of digestive system process;GO:0045472//response to ether;GO:0045776//negative regulation of blood pressure;GO:0045777//positive regulation of blood pressure;GO:0045778//positive regulation of ossification;GO:0045925//positive regulation of female receptivity;GO:0048545//response to steroid hormone;GO:0050806//positive regulation of synaptic transmission;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0051602//response to electrical stimulus;GO:0051930//regulation of sensory perception of pain;GO:0051965//positive regulation of synapse assembly;GO:0060179//male mating behavior;GO:0060406//positive regulation of penile erection;GO:0060450//positive regulation of hindgut contraction;GO:0060455//negative regulation of gastric acid secretion;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000101407	7.798	7.847	6.952	7.024	7.668	6.981	616	623	405	411	511	401	TTI1	TELO2 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29029]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20403	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0070209//ASTRA complex;GO:0110078//TTT complex	GO:0005515//protein binding	GO:0006338//chromatin remodeling;GO:0032006//regulation of TOR signaling;GO:0050821//protein stabilization;GO:2000003//positive regulation of DNA damage checkpoint	--
ENSG00000101412	2.025	2.282	2.257	1.5	1.188	1.798	113	128	93	62	56	73	E2F1	E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Transport and catabolism;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05226//Gastric cancer;ko04110//Cell cycle;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04137//Mitophagy - animal;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05219//Bladder cancer	K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454;K17454	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0032991//protein-containing complex;GO:0035189//Rb-E2F complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001216//DNA-binding transcription activator activity;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000077//DNA damage checkpoint signaling;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010628//positive regulation of gene expression;GO:0030900//forebrain development;GO:0043065//positive regulation of apoptotic process;GO:0043276//anoikis;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0048255//mRNA stabilization;GO:0051726//regulation of cell cycle;GO:0060252//positive regulation of glial cell proliferation;GO:0070345//negative regulation of fat cell proliferation;GO:0071398//cellular response to fatty acid;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1990086//lens fiber cell apoptotic process;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	E2F
ENSG00000101413	9.483	10.639	9.242	9.128	8.884	9.082	716	674	479	515	557	462	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016591//RNA polymerase II, holoenzyme"	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008284//positive regulation of cell population proliferation;GO:0010564//regulation of cell cycle process;GO:0031124//mRNA 3'-end processing;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000101417	4.807	5.05	7.512	6.651	7.859	6.517	341	369.04	329	301	375	313	PXMP4	peroxisomal membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:15920]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13350	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000101421	50.137	50.061	52.605	50.338	50.76	50.461	1666	1672	1291	1239	1425	1220	CHMP4B	charged multivesicular body protein 4B [Source:HGNC Symbol;Acc:HGNC:16171]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12194;K12194	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0000281//mitotic cytokinesis;GO:0001778//plasma membrane repair;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0010458//exit from mitosis;GO:0010506//regulation of autophagy;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0031468//nuclear membrane reassembly;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0036438//maintenance of lens transparency;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046755//viral budding;GO:0046761//viral budding from plasma membrane;GO:0051258//protein polymerization;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0090611//ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway;GO:0097352//autophagosome maturation;GO:1901215//negative regulation of neuron death;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000101425	0	0	0	0	0	0	0	0	0	0	0	0	BPI	bactericidal permeability increasing protein [Source:HGNC Symbol;Acc:HGNC:1095]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0008289//lipid binding	GO:0006955//immune response;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032715//negative regulation of interleukin-6 production;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0042742//defense response to bacterium;GO:0043031//negative regulation of macrophage activation;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000101435	0	0	0	0	0	0	0	0	0	0	0	0	CST9L	cystatin 9 like [Source:HGNC Symbol;Acc:HGNC:16233]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019730//antimicrobial humoral response	--
ENSG00000101438	0	0	0	0	0	0	0	0	0	0	0	0	SLC32A1	solute carrier family 32 member 1 [Source:HGNC Symbol;Acc:HGNC:11018]	Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Nervous system;Substance dependence;Nervous system;Nervous system;Substance dependence	ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle;ko05033//Nicotine addiction	K15015;K15015;K15015;K15015;K15015	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043229//intracellular organelle;GO:0044292//dendrite terminus;GO:0044306//neuron projection terminus;GO:0044316//cone cell pedicle;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0051286//cell tip;GO:0060077//inhibitory synapse;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0098982//GABA-ergic synapse	GO:0015171//amino acid transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015495//gamma-aminobutyric acid:proton symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0007269//neurotransmitter secretion;GO:0007568//aging;GO:0015812//gamma-aminobutyric acid transport;GO:0015816//glycine transport;GO:0021766//hippocampus development;GO:0098700//neurotransmitter loading into synaptic vesicle	--
ENSG00000101439	4036.132	4335.702	4521.818	4612.394	4695.199	4633.861	66552	71823	55067	56320	65385	55601	CST3	cystatin C [Source:HGNC Symbol;Acc:HGNC:2475]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13899	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0001540//amyloid-beta binding;GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding	GO:0006952//defense response;GO:0010466//negative regulation of peptidase activity;GO:0010711//negative regulation of collagen catabolic process;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0010951//negative regulation of endopeptidase activity;GO:0034103//regulation of tissue remodeling;GO:0045861//negative regulation of proteolysis;GO:0060311//negative regulation of elastin catabolic process;GO:0060313//negative regulation of blood vessel remodeling;GO:0097435//supramolecular fiber organization	--
ENSG00000101440	0	0	0	0	0	0	0	0	0	0	0	0	ASIP	agouti signaling protein [Source:HGNC Symbol;Acc:HGNC:745]	Organismal Systems	Endocrine system	ko04916//Melanogenesis	K08725	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005184//neuropeptide hormone activity;GO:0031779//melanocortin receptor binding;GO:0031781//type 3 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding	"GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008343//adult feeding behavior;GO:0009755//hormone-mediated signaling pathway;GO:0032402//melanosome transport;GO:0032438//melanosome organization;GO:0040029//regulation of gene expression, epigenetic;GO:0042438//melanin biosynthetic process;GO:0043473//pigmentation;GO:0048023//positive regulation of melanin biosynthetic process;GO:0071514//genetic imprinting"	--
ENSG00000101441	0	0	0	0	0	0	0	0	0	0	0	0	CST4	cystatin S [Source:HGNC Symbol;Acc:HGNC:2476]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13900	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001895//retina homeostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0045861//negative regulation of proteolysis	--
ENSG00000101442	1.609	1.676	2.999	1.508	2.084	2.237	85	89	117	59	93	86	ACTR5	actin related protein 5 [Source:HGNC Symbol;Acc:HGNC:14671]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031011//Ino80 complex	GO:0005515//protein binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0070914//UV-damage excision repair;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000101443	14.795	13.398	15.113	17.678	16.136	19.613	174	159	132	154	161	168	WFDC2	WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response;GO:0052547//regulation of peptidase activity	--
ENSG00000101444	72.362	77.984	78.454	85.944	80.368	74.643	3227	3496	2584	2839	3028	2422	AHCY	adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K01251;K01251	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0004013//adenosylhomocysteinase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006730//one-carbon metabolic process;GO:0033353//S-adenosylmethionine cycle	--
ENSG00000101445	0.008	0.016	0	0	0.028	0.011	1	2	0	0	3	1	PPP1R16B	protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0017020//myosin phosphatase regulator activity;GO:0019888//protein phosphatase regulator activity	GO:0001938//positive regulation of endothelial cell proliferation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0035304//regulation of protein dephosphorylation;GO:0035307//positive regulation of protein dephosphorylation;GO:0035308//negative regulation of protein dephosphorylation;GO:0050790//regulation of catalytic activity;GO:0051489//regulation of filopodium assembly;GO:0061028//establishment of endothelial barrier;GO:1902309//negative regulation of peptidyl-serine dephosphorylation;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903670//regulation of sprouting angiogenesis	--
ENSG00000101446	0	0	0	0	0	0	0	0	0	0	0	0	SPINT3	"serine peptidase inhibitor, Kunitz type 3 [Source:HGNC Symbol;Acc:HGNC:11248]"	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0048019//receptor antagonist activity;GO:0050431//transforming growth factor beta binding	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000101447	0.671	0.607	0.578	0.553	0.506	0.559	33	30	21	21	21	20	FAM83D	family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding	GO:0001837//epithelial to mesenchymal transition;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0016477//cell migration;GO:0032006//regulation of TOR signaling;GO:0042176//regulation of protein catabolic process;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:1902480//protein localization to mitotic spindle;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000101448	0	0	0	0	0	0	0	0	0	0	0	0	EPPIN	epididymal peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:15932]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0032991//protein-containing complex;GO:0097524//sperm plasma membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0042742//defense response to bacterium;GO:0043086//negative regulation of catalytic activity;GO:0052547//regulation of peptidase activity;GO:0090281//negative regulation of calcium ion import;GO:1901318//negative regulation of flagellated sperm motility	--
ENSG00000101452	3.086	3.713	2.831	2.506	2.72	3.289	177	188	135	126	158	154	DHX35	DEAH-box helicase 35 [Source:HGNC Symbol;Acc:HGNC:15861]	-	-	-	-	GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000101457	12.472	15.103	13.272	12.407	12.577	11.9	327	398	257	238	274	227	DNTTIP1	deoxynucleotidyltransferase terminal interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16160]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042803//protein homodimerization activity	-	--
ENSG00000101460	20.71	22.738	24.775	31.884	23.672	29.179	383	422	324	425	369	400	MAP1LC3A	microtubule associated protein 1 light chain 3 alpha [Source:HGNC Symbol;Acc:HGNC:6838]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Transport and catabolism;Signal transduction;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04216//Ferroptosis	K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044754//autolysosome;GO:0045202//synapse	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008017//microtubule binding;GO:0008429//phosphatidylethanolamine binding;GO:0031625//ubiquitin protein ligase binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0010040//response to iron(II) ion;GO:0010288//response to lead ion;GO:0016236//macroautophagy;GO:0031667//response to nutrient levels;GO:0034198//cellular response to amino acid starvation;GO:0043278//response to morphine;GO:0070301//cellular response to hydrogen peroxide;GO:0071280//cellular response to copper ion;GO:0097352//autophagosome maturation	--
ENSG00000101463	1.475	1.123	1.217	2.022	1.937	2.692	64	49	39	65	71	85	SYNDIG1	synapse differentiation inducing 1 [Source:HGNC Symbol;Acc:HGNC:15885]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0035254//glutamate receptor binding;GO:0042803//protein homodimerization activity	GO:0006886//intracellular protein transport;GO:0051965//positive regulation of synapse assembly;GO:0097091//synaptic vesicle clustering	--
ENSG00000101464	16.62	17.354	16.409	20.464	20.96	18.597	565	593	412	513	602	460	PIGU	phosphatidylinositol glycan anchor biosynthesis class U [Source:HGNC Symbol;Acc:HGNC:15791]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05293;K05293	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042765//GPI-anchor transamidase complex	GO:0005515//protein binding;GO:0034235//GPI anchor binding	GO:0006506//GPI anchor biosynthetic process;GO:0016255//attachment of GPI anchor to protein;GO:0034394//protein localization to cell surface;GO:0046425//regulation of receptor signaling pathway via JAK-STAT	--
ENSG00000101470	0	0	0.096	0.096	0	0.292	0	0	1	1	0	3	TNNC2	"troponin C2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11944]"	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K12042	GO:0005829//cytosol;GO:0005861//troponin complex	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0006937//regulation of muscle contraction	--
ENSG00000101473	15.079	17.798	19.674	18.053	19.246	19.628	348.38	413.79	332.52	311.1	379.21	326.32	ACOT8	acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00120//Primary bile acid biosynthesis	K11992;K11992;K11992	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0003986//acetyl-CoA hydrolase activity;GO:0004778//succinyl-CoA hydrolase activity;GO:0005515//protein binding;GO:0016289//CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0033882//choloyl-CoA hydrolase activity;GO:0044466//glutaryl-CoA hydrolase activity;GO:0047603//acetoacetyl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0047994//hydroxymethylglutaryl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006699//bile acid biosynthetic process;GO:0007031//peroxisome organization;GO:0009062//fatty acid catabolic process;GO:0016559//peroxisome fission;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0036109//alpha-linolenic acid metabolic process;GO:0043649//dicarboxylic acid catabolic process;GO:0044238//primary metabolic process;GO:0044281//small molecule metabolic process;GO:0045225//negative regulation of CD4 production;GO:0071704//organic substance metabolic process	--
ENSG00000101474	53.671	56.917	55.463	58.323	55.199	59.621	2451	2613	1870	1973	2130	1981	APMAP	adipocyte plasma membrane associated protein [Source:HGNC Symbol;Acc:HGNC:13238]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004064//arylesterase activity;GO:0005515//protein binding;GO:0016844//strictosidine synthase activity	GO:0008150//biological_process;GO:0009058//biosynthetic process	--
ENSG00000101489	0.36	0.189	0.345	0.23	0.337	0.313	19	10	14	9	15	12	CELF4	CUGBP Elav-like family member 4 [Source:HGNC Symbol;Acc:HGNC:14015]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0036002//pre-mRNA binding;GO:0042835//BRE binding"	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0007281//germ cell development;GO:0008380//RNA splicing;GO:0009792//embryo development ending in birth or egg hatching;GO:0017148//negative regulation of translation;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:1902866//regulation of retina development in camera-type eye"	--
ENSG00000101493	3.515	5.552	4.241	3.599	4.351	3.401	486	440	353	288	347	342	ZNF516	zinc finger protein 516 [Source:HGNC Symbol;Acc:HGNC:28990]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K22411	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009409//response to cold;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050873//brown fat cell differentiation;GO:0060612//adipose tissue development;GO:0120162//positive regulation of cold-induced thermogenesis"	zf-C2H2
ENSG00000101542	0.852	1.203	0.727	0.935	0.797	0.934	59	83	39	51	46	45	CDH20	cadherin 20 [Source:HGNC Symbol;Acc:HGNC:1760]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000101544	5.997	5.906	6.542	6.63	6.152	5.705	623	635	502	445	556	431	ADNP2	ADNP homeobox 2 [Source:HGNC Symbol;Acc:HGNC:23803]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0030182//neuron differentiation;GO:0030307//positive regulation of cell growth;GO:0034599//cellular response to oxidative stress;GO:0060548//negative regulation of cell death;GO:0071300//cellular response to retinoic acid	Others
ENSG00000101546	2.865	2.692	2.958	2.824	3.47	3.196	145	156	103	114	124	127	RBFA	ribosome binding factor A [Source:HGNC Symbol;Acc:HGNC:26120]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0008150//biological_process	--
ENSG00000101557	15.856	14.359	13.197	11.889	11.595	14.702	946	827	571	527	579	592	USP14	ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612]	-	-	-	-	GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070628//proteasome binding	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007268//chemical synaptic transmission;GO:0010951//negative regulation of endopeptidase activity;GO:0016579//protein deubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0050920//regulation of chemotaxis;GO:0061136//regulation of proteasomal protein catabolic process;GO:1903070//negative regulation of ER-associated ubiquitin-dependent protein catabolic process	--
ENSG00000101558	33.105	29.836	30.2	30.478	27.516	32.87	2421	2250.76	1589	1562	1732.2	1651.46	VAPA	VAMP associated protein A [Source:HGNC Symbol;Acc:HGNC:12648]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K06096	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0035577//azurophil granule membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019904//protein domain specific binding;GO:0033149//FFAT motif binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	GO:0006686//sphingomyelin biosynthetic process;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0008219//cell death;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0019076//viral release from host cell;GO:0031175//neuron projection development;GO:0035627//ceramide transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044828//negative regulation by host of viral genome replication;GO:0044829//positive regulation by host of viral genome replication;GO:0061025//membrane fusion;GO:0070972//protein localization to endoplasmic reticulum;GO:0090114//COPII-coated vesicle budding	--
ENSG00000101574	4.068	2.708	3.16	2.155	2.633	4.391	252	208	150	122	170	202	METTL4	"methyltransferase 4, N6-adenosine [Source:HGNC Symbol;Acc:HGNC:24726]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0009007//site-specific DNA-methyltransferase (adenine-specific) activity;GO:0016740//transferase activity;GO:0106347//U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity	GO:0001510//RNA methylation;GO:0006325//chromatin organization;GO:0032259//methylation;GO:0032775//DNA methylation on adenine;GO:0043414//macromolecule methylation;GO:0043484//regulation of RNA splicing;GO:0060255//regulation of macromolecule metabolic process;GO:0090296//regulation of mitochondrial DNA replication;GO:0090304//nucleic acid metabolic process;GO:0120049//snRNA (adenine-N6)-methylation;GO:1902275//regulation of chromatin organization;GO:1903108//regulation of mitochondrial transcription	--
ENSG00000101577	18.43	17.194	17.017	13.858	14.53	16.955	2250	2172	1579	1256	1541	1550	LPIN2	lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine and metabolic disease;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04150//mTOR signaling pathway;ko04936//Alcoholic liver disease;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K15728;K15728;K15728;K15728;K15728	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0003713//transcription coactivator activity;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0016311//dephosphorylation;GO:0019432//triglyceride biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0044255//cellular lipid metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000101596	9.834	7.066	6.541	4.753	5.488	6.723	1284	843	601	466	601	611	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29090]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0001740//Barr body;GO:0005694//chromosome;GO:0035861//site of double-strand break"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042803//protein homodimerization activity	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0043584//nose development;GO:0045739//positive regulation of DNA repair;GO:0051276//chromosome organization;GO:0060820//inactivation of X chromosome by heterochromatin assembly;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000101605	0.374	0.346	0.229	0.468	0.41	0.328	40	41	20	38	38	27	MYOM1	myomesin 1 [Source:HGNC Symbol;Acc:HGNC:7613]	-	-	-	-	GO:0005737//cytoplasm;GO:0005863//striated muscle myosin thick filament;GO:0030017//sarcomere;GO:0031430//M band;GO:0032982//myosin filament	GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0010628//positive regulation of gene expression;GO:0010737//protein kinase A signaling;GO:0050714//positive regulation of protein secretion	--
ENSG00000101608	118.277	116.757	104.722	113.317	106.483	101.942	2340	2316	1531	1665	1781	1469	MYL12A	myosin light chain 12A [Source:HGNC Symbol;Acc:HGNC:16701]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Development and regeneration;Cellular community - eukaryotes;Immune system;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04360//Axon guidance;ko04530//Tight junction;ko04611//Platelet activation;ko04670//Leukocyte transendothelial migration	K12757;K12757;K12757;K12757;K12757;K12757;K12757;K12757	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0032036//myosin heavy chain binding;GO:0046872//metal ion binding	GO:0070527//platelet aggregation	--
ENSG00000101624	2.93	2.704	4.141	2.63	2.108	3.614	148	123	118	74	102	97	CEP76	centrosomal protein 76 [Source:HGNC Symbol;Acc:HGNC:25727]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0046599//regulation of centriole replication	--
ENSG00000101638	0.064	0	0	0	0	0.044	2	0	0	0	0	1	ST8SIA5	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:17827]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03369;K03369	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation	--
ENSG00000101639	3.095	2.295	2.638	2.075	2.271	2.349	446	378	305	231	304	248	CEP192	centrosomal protein 192 [Source:HGNC Symbol;Acc:HGNC:25515]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0120098//procentriole;GO:0120099//procentriole replication complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding	GO:0007099//centriole replication;GO:0009617//response to bacterium;GO:0051298//centrosome duplication;GO:0071539//protein localization to centrosome;GO:0090222//centrosome-templated microtubule nucleation;GO:0090307//mitotic spindle assembly	--
ENSG00000101654	13.959	11.949	10.813	9.777	10.019	11.295	1507	1295	852	762	914	893	RNMT	RNA guanine-7 methyltransferase [Source:HGNC Symbol;Acc:HGNC:10075]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K00565	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005845//mRNA cap binding complex;GO:0031533//mRNA cap methyltransferase complex;GO:0043235//receptor complex	GO:0003723//RNA binding;GO:0004482//mRNA (guanine-N7-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0032259//methylation;GO:0106005//RNA 5'-cap (guanine-N7)-methylation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000101665	5.666	5.214	5.963	6.508	4.435	4.13	344	301	231	173	250	204	SMAD7	SMAD family member 7 [Source:HGNC Symbol;Acc:HGNC:6773]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K19631;K19631	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0032991//protein-containing complex;GO:0071144//heteromeric SMAD protein complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008013//beta-catenin binding;GO:0031625//ubiquitin protein ligase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0070411//I-SMAD binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0002725//negative regulation of T cell cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0022409//positive regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030279//negative regulation of ossification;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0031503//protein-containing complex localization;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032925//regulation of activin receptor signaling pathway;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034333//adherens junction assembly;GO:0034616//response to laminar fluid shear stress;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0048844//artery morphogenesis;GO:0050821//protein stabilization;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055117//regulation of cardiac muscle contraction;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902731//negative regulation of chondrocyte proliferation;GO:1903043//positive regulation of chondrocyte hypertrophy;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000317//negative regulation of T-helper 17 type immune response;GO:2000320//negative regulation of T-helper 17 cell differentiation"	MH1
ENSG00000101670	69.767	73.793	68.62	54.123	62.901	68.204	5456	5670	4019	3454	4287	3702	LIPG	"lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623]"	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04979//Cholesterol metabolism	K22284;K22284;K22284	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0009986//cell surface	GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008970//phospholipase A1 activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007584//response to nutrient;GO:0008283//cell population proliferation;GO:0009395//phospholipid catabolic process;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0032376//positive regulation of cholesterol transport;GO:0034375//high-density lipoprotein particle remodeling;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0050746//regulation of lipoprotein metabolic process;GO:0055091//phospholipid homeostasis	--
ENSG00000101680	0.51	0.517	0.156	0.655	0.74	0.495	102	104	23	97	125	72	LAMA1	laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Cardiovascular disease;Cardiovascular disease;Infectious disease: parasitic;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005606//laminin-1 complex;GO:0005608//laminin-3 complex;GO:0005615//extracellular space;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0043256//laminin complex;GO:0062023//collagen-containing extracellular matrix;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043208//glycosphingolipid binding	GO:0002011//morphogenesis of an epithelial sheet;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007411//axon guidance;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0031175//neuron projection development;GO:0043010//camera-type eye development;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045785//positive regulation of cell adhesion;GO:0045995//regulation of embryonic development;GO:0048514//blood vessel morphogenesis;GO:0051149//positive regulation of muscle cell differentiation;GO:0060041//retina development in camera-type eye;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0061304//retinal blood vessel morphogenesis;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000101695	0.095	0.052	0.105	0.093	0.092	0.024	11	6	9	8	9	2	RNF125	ring finger protein 125 [Source:HGNC Symbol;Acc:HGNC:21150]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12170	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0039536//negative regulation of RIG-I signaling pathway;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000101745	0.571	0.553	0.351	0.336	0.389	0.458	108	88	49	47	64	63	ANKRD12	ankyrin repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:29135]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000101746	0.025	0	0.034	0	0	0.179	1	0	1	0	0	5	NOL4	nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000101751	5.274	3.018	4.274	3.442	3.5	5.226	304	183	177	152	180	212	POLI	DNA polymerase iota [Source:HGNC Symbol;Acc:HGNC:9182]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K03510	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006974//cellular response to DNA damage stimulus;GO:0019985//translesion synthesis;GO:0042276//error-prone translesion synthesis;GO:0071897//DNA biosynthetic process	--
ENSG00000101752	17.413	12.856	12.836	9.595	10.26	10.838	3648	2707	1986	1489	1816	1652	MIB1	MIB E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21086]	Human Diseases	Cardiovascular disease	ko05417//Lipid and atherosclerosis	K10645	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001841//neural tube formation;GO:0001947//heart looping;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0007507//heart development;GO:0016567//protein ubiquitination;GO:0045665//negative regulation of neuron differentiation;GO:0045807//positive regulation of endocytosis	--
ENSG00000101773	9.356	7.671	6.55	5.733	7.373	6.438	598	487	316	256	299	298	RBBP8	"RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891]"	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K20773	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0017053//transcription repressor complex;GO:0035861//site of double-strand break;GO:0043231//intracellular membrane-bounded organelle;GO:0070533//BRCA1-C complex	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0000403//Y-form DNA binding;GO:0000406//double-strand/single-strand DNA junction binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070336//flap-structured DNA binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000724//double-strand break repair via homologous recombination;GO:0001835//blastocyst hatching;GO:0006281//DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0035825//homologous recombination;GO:0044818//mitotic G2/M transition checkpoint;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0110025//DNA strand resection involved in replication fork processing;GO:1905168//positive regulation of double-strand break repair via homologous recombination"	--
ENSG00000101782	17.786	15.015	14.301	13.003	14.588	14.406	1230	1054	708	714	825	760	RIOK3	RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor"	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0089720//caspase binding;GO:0106310//protein serine kinase activity	GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007059//chromosome segregation;GO:0016310//phosphorylation;GO:0030490//maturation of SSU-rRNA;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032728//positive regulation of interferon-beta production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0042254//ribosome biogenesis;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus;GO:0071359//cellular response to dsRNA;GO:0098586//cellular response to virus;GO:1990786//cellular response to dsDNA	--
ENSG00000101811	5.02	4.959	5.592	4.607	5.415	4.476	235	230	166	180	177	163	CSTF2	cleavage stimulation factor subunit 2 [Source:HGNC Symbol;Acc:HGNC:2484]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14407	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0016604//nuclear body;GO:0071920//cleavage body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0016070//RNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000101812	0	0	0	0	0.03	0	0	0	0	0	1	0	H2BW2	H2B.W histone 2 [Source:HGNC Symbol;Acc:HGNC:27867]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000101825	14.895	16.786	6.945	7.482	9.924	8.354	3029	3431	1043	1127	1705	1236	MXRA5	matrix remodeling associated 5 [Source:HGNC Symbol;Acc:HGNC:7539]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0071559//response to transforming growth factor beta	--
ENSG00000101842	0.048	0	0.022	0.043	0	0	3	0	1	2	0	0	VSIG1	V-set and immunoglobulin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28675]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding	GO:0003382//epithelial cell morphogenesis;GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000101843	29.429	29.003	30.959	27.975	26.391	27.256	862	840	666	603	655	582	PSMD10	"proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]"	-	-	-	-	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0045111//intermediate filament cytoskeleton"	GO:0005515//protein binding;GO:0008134//transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0030307//positive regulation of cell growth;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0070682//proteasome regulatory particle assembly;GO:0090201//negative regulation of release of cytochrome c from mitochondria"	--
ENSG00000101844	5.922	6.082	5.58	6.024	6.046	6.505	266	280	186	187	220	207	ATG4A	autophagy related 4A cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:16489]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K08342;K08342	GO:0005737//cytoplasm	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019786//Atg8-specific protease activity	GO:0006508//proteolysis;GO:0006914//autophagy;GO:0015031//protein transport;GO:0051697//protein delipidation	--
ENSG00000101846	2.347	2.209	1.719	2.352	2.318	2.167	315	298	168.47	236	266.03	214	STS	steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K01131;K01131	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity	-	--
ENSG00000101849	29.345	26.556	27.483	26.975	24.586	24.81	3065	2998	2277	2043	2360	1941	TBL1X	transducin beta like 1 X-linked [Source:HGNC Symbol;Acc:HGNC:11585]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04508	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0072686//mitotic spindle	GO:0000976//transcription cis-regulatory region binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0007605//sensory perception of sound;GO:0016575//histone deacetylation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0090263//positive regulation of canonical Wnt signaling pathway"	--
ENSG00000101850	184.979	186.039	217.534	247.38	210.524	236.263	5970	6027	5278	5674	5654	5573	GPR143	G protein-coupled receptor 143 [Source:HGNC Symbol;Acc:HGNC:20145]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0035240//dopamine binding;GO:0035643//L-DOPA receptor activity;GO:0072544//L-DOPA binding;GO:0072545//tyrosine binding	GO:0006726//eye pigment biosynthetic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007601//visual perception;GO:0032400//melanosome localization;GO:0032402//melanosome transport;GO:0032438//melanosome organization;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050848//regulation of calcium-mediated signaling;GO:1902908//regulation of melanosome transport;GO:1903056//regulation of melanosome organization	--
ENSG00000101856	85.644	79.042	76.968	81.948	85.984	94.05	3322	3084	2206	2353	2823	2660	PGRMC1	progesterone receptor membrane component 1 [Source:HGNC Symbol;Acc:HGNC:16090]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0035579//specific granule membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0045202//synapse	GO:0001540//amyloid-beta binding;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006783//heme biosynthetic process	--
ENSG00000101868	3.297	2.85	2.972	1.991	2.13	2.491	372	326	247	162	204	206	POLA1	"DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173]"	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02320	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005658//alpha DNA polymerase:primase complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0043625//delta DNA polymerase complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0017076//purine nucleotide binding;GO:0019103//pyrimidine nucleotide binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006272//leading strand elongation;GO:0006273//lagging strand elongation;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0032479//regulation of type I interferon production;GO:0071897//DNA biosynthetic process;GO:1902975//mitotic DNA replication initiation"	--
ENSG00000101871	6.815	6.583	6.472	5.385	5.709	6.258	801	686	522	422	478	455	MID1	midline 1 [Source:HGNC Symbol;Acc:HGNC:7095]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K08285	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding	GO:0000226//microtubule cytoskeleton organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0007389//pattern specification process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0035372//protein localization to microtubule	--
ENSG00000101882	3.869	5.566	5.841	3.404	2.883	4.277	207	280	209	179	160	163	NKAP	NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030097//hemopoiesis;GO:0030851//granulocyte differentiation;GO:0033077//T cell differentiation in thymus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0071425//hematopoietic stem cell proliferation"	--
ENSG00000101883	0	0	0	0	0	0	0	0	0	0	0	0	RHOXF1	Rhox homeobox family member 1 [Source:HGNC Symbol;Acc:HGNC:29993]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0030521//androgen receptor signaling pathway;GO:0048484//enteric nervous system development"	Homeobox
ENSG00000101888	4.614	3.579	4.225	4.285	3.76	3.701	197	160	136	123	135	126	NXT2	nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14285;K14285;K14285;K14285;K14285	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042272//nuclear RNA export factor complex;GO:0044613//nuclear pore central transport channel;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000101890	0	0.013	0	0	0	0.036	0	1	0	0	0	2	GUCY2F	"guanylate cyclase 2F, retinal [Source:HGNC Symbol;Acc:HGNC:4691]"	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04744//Phototransduction	K12322;K12322;K12322	GO:0005640//nuclear outer membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0097381//photoreceptor disc membrane;GO:0120200//rod photoreceptor outer segment	GO:0000166//nucleotide binding;GO:0001653//peptide receptor activity;GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006182//cGMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007601//visual perception;GO:0009190//cyclic nucleotide biosynthetic process;GO:0019934//cGMP-mediated signaling;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0035556//intracellular signal transduction;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception	--
ENSG00000101892	0	0.01	0	0	0.03	0	0	1	0	0	2	0	ATP1B4	ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005887//integral component of plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022890//inorganic cation transmembrane transporter activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0098655//cation transmembrane transport"	--
ENSG00000101898	0.576	1.861	1.656	1.069	1.789	0.791	8	26	17	11	21	8	MCTS2P	"MCTS family member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:49760]"	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding	GO:0001731//formation of translation preinitiation complex	--
ENSG00000101901	12.695	11.783	12.395	10.859	14.927	12.575	288	266	188	208	254	184	ALG13	ALG13 UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:30881]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K07432;K07432;K07432	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004577//N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0016787//hydrolase activity	GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006508//proteolysis;GO:0008152//metabolic process	--
ENSG00000101911	19.543	14.738	16.524	11.57	14.59	17.868	669	580	506	325	397	383	PRPS2	phosphoribosyl pyrophosphate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:9465]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00948;K00948;K00948;K00948;K00948	GO:0002189//ribose phosphate diphosphokinase complex;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019003//GDP binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0046872//metal ion binding	GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0019693//ribose phosphate metabolic process;GO:0031100//animal organ regeneration;GO:0044249//cellular biosynthetic process	--
ENSG00000101916	0	0	0	0	0	0	0	0	0	0	0	0	TLR8	toll like receptor 8 [Source:HGNC Symbol;Acc:HGNC:15632]	Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Immune system	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko04620//Toll-like receptor signaling pathway	K10170;K10170;K10170	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036020//endolysosome membrane	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0038187//pattern recognition receptor activity;GO:0042802//identical protein binding	GO:0001817//regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009615//response to virus;GO:0016064//immunoglobulin mediated immune response;GO:0032695//negative regulation of interleukin-12 production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0034158//toll-like receptor 8 signaling pathway;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000101928	9.382	7.822	7.64	7.17	7.313	8.857	361	341	248	242	255	282	MOSPD1	motile sperm domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25235]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000101935	1.712	1.891	1.135	1.397	1.045	1.201	190	202	93	104	98	97	AMMECR1	AMMECR nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:467]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000101938	1.192	0.969	1.093	0.668	1.04	0.584	82	78	41	34	51	34	CHRDL1	chordin like 1 [Source:HGNC Symbol;Acc:HGNC:29861]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0036122//BMP binding;GO:0050431//transforming growth factor beta binding	GO:0000578//embryonic axis specification;GO:0001503//ossification;GO:0001654//eye development;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0060074//synapse maturation;GO:0097113//AMPA glutamate receptor clustering;GO:0098976//excitatory chemical synaptic transmission	--
ENSG00000101940	29.459	26.482	28.882	30.477	30.552	28.045	966	1094.01	867	902	1043	864	WDR13	WD repeat domain 13 [Source:HGNC Symbol;Acc:HGNC:14352]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:1990841//promoter-specific chromatin binding	GO:1904691//negative regulation of type B pancreatic cell proliferation	--
ENSG00000101945	1.833	2.051	1.837	1.38	1.962	1.405	104	117	77	58	95	58	SUV39H1	SUV39H1 histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:11479]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11419;K11419	"GO:0000775//chromosome, centromeric region;GO:0000792//heterochromatin;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0033553//rDNA heterochromatin;GO:0061773//eNoSc complex"	GO:0000976//transcription cis-regulatory region binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0047485//protein N-terminus binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000183//rDNA heterochromatin assembly;GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0030154//cell differentiation;GO:0031062//positive regulation of histone methylation;GO:0031065//positive regulation of histone deacetylation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0036123//histone H3-K9 dimethylation;GO:0036124//histone H3-K9 trimethylation;GO:0042149//cellular response to glucose starvation;GO:0042754//negative regulation of circadian rhythm;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046015//regulation of transcription by glucose;GO:0048511//rhythmic process;GO:0071456//cellular response to hypoxia;GO:0097009//energy homeostasis"	--
ENSG00000101951	0	0	0	0	0	0	0	0	0	0	0	0	PAGE4	PAGE family member 4 [Source:HGNC Symbol;Acc:HGNC:4108]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006979//response to oxidative stress;GO:0032872//regulation of stress-activated MAPK cascade;GO:0042594//response to starvation;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:1903427//negative regulation of reactive oxygen species biosynthetic process"	--
ENSG00000101955	1.455	1.362	1.025	0.848	1.29	0.726	55	52	29	24	41	20	SRPX	sushi repeat containing protein X-linked [Source:HGNC Symbol;Acc:HGNC:11309]	-	-	-	-	GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0001845//phagolysosome assembly;GO:0006914//autophagy;GO:0007155//cell adhesion;GO:0034976//response to endoplasmic reticulum stress;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000101958	0.088	0.045	0.113	0.038	0	0.021	4	3	3	1	0	1	GLRA2	glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05194	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098690//glycinergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0016594//glycine binding;GO:0016934//extracellularly glycine-gated chloride channel activity;GO:0022824//transmitter-gated ion channel activity;GO:0022852//glycine-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0046872//metal ion binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043200//response to amino acid;GO:0050877//nervous system process;GO:0060012//synaptic transmission, glycinergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0071230//cellular response to amino acid stimulus;GO:0071294//cellular response to zinc ion;GO:0071361//cellular response to ethanol;GO:1902476//chloride transmembrane transport"	--
ENSG00000101966	8.495	5.932	8.796	3.923	4.891	7.944	1009	742	577	508	656	608	XIAP	X-linked inhibitor of apoptosis [Source:HGNC Symbol;Acc:HGNC:592]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Genetic Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	"Cancer: overview;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Folding, sorting and degradation;Cell growth and death;Infectious disease: parasitic;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death"	ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04120//Ubiquitin mediated proteolysis;ko04210//Apoptosis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko01524//Platinum drug resistance;ko04215//Apoptosis - multiple species	K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725;K04725	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005876//spindle microtubule	GO:0004842//ubiquitin-protein transferase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0120283//protein serine/threonine kinase binding	GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010466//negative regulation of peptidase activity;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0030510//regulation of BMP signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0032268//regulation of cellular protein metabolic process;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045088//regulation of innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050727//regulation of inflammatory response;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0052548//regulation of endopeptidase activity;GO:0055070//copper ion homeostasis;GO:0060785//regulation of apoptosis involved in tissue homeostasis;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097340//inhibition of cysteine-type endopeptidase activity;GO:1902530//positive regulation of protein linear polyubiquitination;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000101972	26.672	16.925	17.443	11.375	14.163	14.267	2464	1540	1195	866	1093	1037	STAG2	stromal antigen 2 [Source:HGNC Symbol;Acc:HGNC:11355]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06671	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0008278//cohesin complex;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0034991//nuclear meiotic cohesin complex;GO:0097431//mitotic spindle pole"	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0090307//mitotic spindle assembly	--
ENSG00000101974	6.312	3.86	4.382	5.048	4.967	5.099	803	523	429	448	504	472	ATP11C	ATPase phospholipid transporting 11C [Source:HGNC Symbol;Acc:HGNC:13554]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090555//phosphatidylethanolamine flippase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140346//phosphatidylserine flippase activity	GO:0002329//pre-B cell differentiation;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:0045579//positive regulation of B cell differentiation;GO:0140331//aminophospholipid translocation	--
ENSG00000101977	0.256	0.228	0.393	0.072	0.436	0.195	12	12	17	3	20	8	MCF2	MCF.2 cell line derived transforming sequence [Source:HGNC Symbol;Acc:HGNC:6940]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0016358//dendrite development;GO:0035556//intracellular signal transduction;GO:0050771//negative regulation of axonogenesis;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000101981	0	0	0	0	0	0	0	0	0	0	0	0	F9	coagulation factor IX [Source:HGNC Symbol;Acc:HGNC:3551]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01321	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0031638//zymogen activation	--
ENSG00000101986	6.65	9.105	7.739	9.295	9.312	8.342	494	688	435	524	591	454	ABCD1	ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04146//Peroxisome;ko02010//ABC transporters	K05675;K05675	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015607//ABC-type fatty-acyl-CoA transporter activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0046982//protein heterodimerization activity;GO:0047617//acyl-CoA hydrolase activity;GO:0140359//ABC-type transporter activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0002082//regulation of oxidative phosphorylation;GO:0006635//fatty acid beta-oxidation;GO:0007031//peroxisome organization;GO:0015910//long-chain fatty acid import into peroxisome;GO:0015916//fatty-acyl-CoA transport;GO:0015919//peroxisomal membrane transport;GO:0030497//fatty acid elongation;GO:0031998//regulation of fatty acid beta-oxidation;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0036109//alpha-linolenic acid metabolic process;GO:0036113//very long-chain fatty-acyl-CoA catabolic process;GO:0042758//long-chain fatty acid catabolic process;GO:0042760//very long-chain fatty acid catabolic process;GO:0043217//myelin maintenance;GO:0043651//linoleic acid metabolic process;GO:0051900//regulation of mitochondrial depolarization;GO:0055085//transmembrane transport;GO:0055089//fatty acid homeostasis;GO:0055092//sterol homeostasis;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900407//regulation of cellular response to oxidative stress;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1990535//neuron projection maintenance;GO:2001280//positive regulation of unsaturated fatty acid biosynthetic process	--
ENSG00000101997	8.411	8.492	9.608	9.862	9.313	8.404	403	409	340	350	377	293	CCDC22	coiled-coil domain containing 22 [Source:HGNC Symbol;Acc:HGNC:28909]	-	-	-	-	GO:0005575//cellular_component;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005829//cytosol	GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0006878//cellular copper ion homeostasis;GO:0006893//Golgi to plasma membrane transport;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000102001	0.082	0.088	0.043	0.09	0.049	0.091	10	11	4	8	5	8	CACNA1F	calcium voltage-gated channel subunit alpha1 F [Source:HGNC Symbol;Acc:HGNC:1393]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Signal transduction;Cancer: overview;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Circulatory system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Cardiovascular disease;Circulatory system;Nervous system;Endocrine system;Cardiovascular disease;Endocrine system;Endocrine system;Endocrine system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04924//Renin secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion"	K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853;K04853	GO:0001750//photoreceptor outer segment;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007601//visual perception;GO:0034765//regulation of ion transmembrane transport;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport	--
ENSG00000102003	9.459	9.778	11.065	15.385	14.063	12.494	339	353	305	387	411	377	SYP	synaptophysin [Source:HGNC Symbol;Acc:HGNC:11506]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0048786//presynaptic active zone;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse	GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0043621//protein self-association	GO:0006897//endocytosis;GO:0016188//synaptic vesicle maturation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048488//synaptic vesicle endocytosis;GO:0048499//synaptic vesicle membrane organization;GO:0071310//cellular response to organic substance;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000474//regulation of opioid receptor signaling pathway	--
ENSG00000102007	29.463	32.598	31.385	33.542	30.482	22.8	674.07	747.32	530.32	568.43	589.19	377.33	PLP2	proteolipid protein 2 [Source:HGNC Symbol;Acc:HGNC:9087]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0019956//chemokine binding	GO:0006811//ion transport;GO:0006935//chemotaxis;GO:0019221//cytokine-mediated signaling pathway;GO:0034220//ion transmembrane transport	--
ENSG00000102010	0	0	0	0	0	0	0	0	0	0	0	0	BMX	BMX non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1079]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032587//ruffle membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0006468//protein phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007498//mesoderm development;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0046777//protein autophosphorylation;GO:0050853//B cell receptor signaling pathway	--
ENSG00000102021	0	0	0	0	0	0	0	0	0	0	0	0	LUZP4	leucine zipper protein 4 [Source:HGNC Symbol;Acc:HGNC:24971]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0051028//mRNA transport	--
ENSG00000102024	68.63	62.143	56.929	48.444	51.432	53.685	4638	4180	2825	2375	2940	2618	PLS3	plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0032432//actin filament bundle	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0051017//actin filament bundle assembly;GO:0051639//actin filament network formation;GO:0060348//bone development	--
ENSG00000102030	25.396	28.859	25.275	22.041	24.733	20.064	614	659	492	478	501	371	NAA10	"N-alpha-acetyltransferase 10, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:18704]"	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031415//NatA complex	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0043022//ribosome binding;GO:1990189//peptide-serine-N-acetyltransferase activity;GO:1990190//peptide-glutamate-N-acetyltransferase activity	"GO:0006323//DNA packaging;GO:0006473//protein acetylation;GO:0006474//N-terminal protein amino acid acetylation;GO:0006475//internal protein amino acid acetylation;GO:0017198//N-terminal peptidyl-serine acetylation;GO:0018002//N-terminal peptidyl-glutamic acid acetylation;GO:2000719//negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric"	--
ENSG00000102032	13.555	15.546	14.435	17.559	14.631	17.133	375	432	294	357	342	343	RENBP	renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01787;K01787	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004857//enzyme inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016853//isomerase activity;GO:0017076//purine nucleotide binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding;GO:0050121//N-acylglucosamine 2-epimerase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006051//N-acetylmannosamine metabolic process;GO:0008217//regulation of blood pressure;GO:0010951//negative regulation of endopeptidase activity;GO:0019262//N-acetylneuraminate catabolic process;GO:0043086//negative regulation of catalytic activity	--
ENSG00000102034	4.757	4.861	4.421	5.438	5.074	5.423	440	452	302	377	388	362	ELF4	E74 like ETS transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3319]	Cellular Processes	Cell growth and death	ko04214//Apoptosis - fly	K09428	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016605//PML body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001787//natural killer cell proliferation;GO:0001866//NK T cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051171//regulation of nitrogen compound metabolic process;GO:0060255//regulation of macromolecule metabolic process;GO:0080090//regulation of primary metabolic process"	ETS
ENSG00000102038	30.254	25.43	23.629	17.293	20.717	24.597	2510	2119	1448	1063	1452	1483	SMARCA1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016589//NURF complex;GO:0043231//intracellular membrane-bounded organelle;GO:0090537//CERF complex;GO:1904949//ATPase complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0031491//nucleosome binding;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0030182//neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000177//regulation of neural precursor cell proliferation"	MYB
ENSG00000102043	1.142	1.01	0.614	0.685	0.901	0.648	63	56	25	28	42	26	MTMR8	myotubularin related protein 8 [Source:HGNC Symbol;Acc:HGNC:16825]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18083;K18083;K18083	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0106018//phosphatidylinositol-3,5-bisphosphate phosphatase activity"	GO:0006629//lipid metabolic process;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0016241//regulation of macroautophagy;GO:0016311//dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000102048	0.03	0.238	0	0.081	0.059	0	1	8	0	2	2	0	ASB9	ankyrin repeat and SOCS box containing 9 [Source:HGNC Symbol;Acc:HGNC:17184]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification;GO:0045732//positive regulation of protein catabolic process	--
ENSG00000102053	0.853	1.067	0.867	1.032	0.927	0.913	108	120	93	90	90	96	ZC3H12B	zinc finger CCCH-type containing 12B [Source:HGNC Symbol;Acc:HGNC:17407]	-	-	-	-	GO:0005634//nucleus;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000102054	44.751	44.79	40.686	38.419	38.595	40.943	2041	2080	1366	1307	1468	1338	RBBP7	"RB binding protein 7, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9890]"	-	-	-	-	"GO:0000118//histone deacetylase complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0016581//NuRD complex;GO:0016589//NURF complex;GO:0035098//ESC/E(Z) complex;GO:1904949//ATPase complex"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0010468//regulation of gene expression;GO:0016575//histone deacetylation;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048545//response to steroid hormone;GO:0070370//cellular heat acclimation;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000102055	0	0	0	0	0	0	0	0	0	0	0	0	PPP1R2C	PPP1R2C family member C [Source:HGNC Symbol;Acc:HGNC:16324]	-	-	-	-	GO:0005575//cellular_component	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0009966//regulation of signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000102057	0.879	0.854	1.252	1.048	1.306	1.208	86	84	87	76	108	86	KCND1	potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000102076	0	0	0	0	0	0	0	0	0	0	0	0	OPN1LW	"opsin 1, long wave sensitive [Source:HGNC Symbol;Acc:HGNC:9936]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097381//photoreceptor disc membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0032467//positive regulation of cytokinesis;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000102078	4.885	3.019	3.215	2.804	3.272	3.378	125	80	71	61	81	73	SLC25A14	solute carrier family 25 member 14 [Source:HGNC Symbol;Acc:HGNC:10984]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0015116//sulfate transmembrane transporter activity;GO:0015117//thiosulfate transmembrane transporter activity;GO:0015131//oxaloacetate transmembrane transporter activity;GO:0015140//malate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006839//mitochondrial transport;GO:0008272//sulfate transport;GO:0009060//aerobic respiration;GO:0015709//thiosulfate transport;GO:0015729//oxaloacetate transport;GO:0035435//phosphate ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071422//succinate transmembrane transport;GO:0071423//malate transmembrane transport;GO:1902356//oxaloacetate(2-) transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000102081	17.89	14.546	13.974	12.073	14.887	15.678	1442	1190	858	744	1023	971	FMR1	FMRP translational regulator 1 [Source:HGNC Symbol;Acc:HGNC:3775]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005845//mRNA cap binding complex;GO:0005886//plasma membrane;GO:0010369//chromocenter;GO:0010494//cytoplasmic stress granule;GO:0014069//postsynaptic density;GO:0015030//Cajal body;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0032433//filopodium tip;GO:0032797//SMN complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0044326//dendritic spine neck;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0071598//neuronal ribonucleoprotein granule;GO:0097386//glial cell projection;GO:0098793//presynapse;GO:0098794//postsynapse;GO:1902737//dendritic filopodium;GO:1990124//messenger ribonucleoprotein complex;GO:1990812//growth cone filopodium;GO:1990904//ribonucleoprotein complex"	GO:0002151//G-quadruplex RNA binding;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008266//poly(U) RNA binding;GO:0030371//translation repressor activity;GO:0031369//translation initiation factor binding;GO:0033592//RNA strand annealing activity;GO:0034046//poly(G) binding;GO:0035064//methylated histone binding;GO:0035197//siRNA binding;GO:0035198//miRNA binding;GO:0035613//RNA stem-loop binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043022//ribosome binding;GO:0044325//transmembrane transporter binding;GO:0045182//translation regulator activity;GO:0046982//protein heterodimerization activity;GO:0048027//mRNA 5'-UTR binding;GO:0070840//dynein complex binding;GO:1990825//sequence-specific mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001934//positive regulation of protein phosphorylation;GO:0002092//positive regulation of receptor internalization;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0006974//cellular response to DNA damage stimulus;GO:0007215//glutamate receptor signaling pathway;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0017148//negative regulation of translation;GO:0031047//gene silencing by RNA;GO:0033129//positive regulation of histone phosphorylation;GO:0034644//cellular response to UV;GO:0043488//regulation of mRNA stability;GO:0044830//modulation by host of viral RNA genome replication;GO:0045727//positive regulation of translation;GO:0045947//negative regulation of translational initiation;GO:0046928//regulation of neurotransmitter secretion;GO:0051028//mRNA transport;GO:0051489//regulation of filopodium assembly;GO:0051491//positive regulation of filopodium assembly;GO:0060964//regulation of gene silencing by miRNA;GO:0060998//regulation of dendritic spine development;GO:0060999//positive regulation of dendritic spine development;GO:0072711//cellular response to hydroxyurea;GO:0098586//cellular response to virus;GO:0098908//regulation of neuronal action potential;GO:1900453//negative regulation of long-term synaptic depression;GO:1901254//positive regulation of intracellular transport of viral material;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902373//negative regulation of mRNA catabolic process;GO:1902416//positive regulation of mRNA binding;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:2000637//positive regulation of gene silencing by miRNA;GO:2000766//negative regulation of cytoplasmic translation;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000102096	3.323	4.386	4.53	4.205	3.63	4.4	143	187	144	128	132	135	PIM2	"Pim-2 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8987]"	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05221//Acute myeloid leukemia	K08806;K08806	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0010508//positive regulation of autophagy;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization"	--
ENSG00000102098	1.34	0.74	0.982	1.008	0.71	1.127	83	46	57	55	49	62	SCML2	Scm polycomb group protein like 2 [Source:HGNC Symbol;Acc:HGNC:10581]	-	-	-	-	GO:0005634//nucleus;GO:0031519//PcG protein complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000102100	14.101	13.966	18.224	16.516	16.598	17.069	486	475	413	398	466	429	SLC35A2	solute carrier family 35 member A2 [Source:HGNC Symbol;Acc:HGNC:11022]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005459//UDP-galactose transmembrane transporter activity;GO:0005515//protein binding;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity	GO:0006012//galactose metabolic process;GO:0008643//carbohydrate transport;GO:0072334//UDP-galactose transmembrane transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport	--
ENSG00000102103	62.419	61.123	64.552	70.457	57.701	64.815	1278	1263	969	1064	1002	961	PQBP1	polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12865	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0071598//neuronal ribonucleoprotein granule	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0031175//neuron projection development;GO:0032481//positive regulation of type I interferon production;GO:0043484//regulation of RNA splicing;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048814//regulation of dendrite morphogenesis;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA"	--
ENSG00000102104	0.016	0	0	0	0	0	1	0	0	0	0	0	RS1	retinoschisin 1 [Source:HGNC Symbol;Acc:HGNC:10457]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0098984//neuron to neuron synapse	"GO:0001786//phosphatidylserine binding;GO:0008289//lipid binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0001654//eye development;GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0010842//retina layer formation;GO:0016062//adaptation of rhodopsin mediated signaling;GO:0050896//response to stimulus;GO:0051260//protein homooligomerization	--
ENSG00000102109	71.118	86.29	80.434	68.579	75.158	68.071	1512	1844	1263	1080	1350	1053	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0030141//secretory granule	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding	GO:0002021//response to dietary excess;GO:0007218//neuropeptide signaling pathway;GO:0009409//response to cold;GO:0010951//negative regulation of endopeptidase activity;GO:0016486//peptide hormone processing	--
ENSG00000102119	28.712	29.491	28.61	35.231	32.105	30.356	682	728	529	648	662	513	EMD	emerin [Source:HGNC Symbol;Acc:HGNC:3331]	Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12569;K12569;K12569	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005819//spindle;GO:0005829//cytosol;GO:0005874//microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031616//spindle pole centrosome;GO:0031965//nuclear membrane;GO:0032541//cortical endoplasmic reticulum	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0048487//beta-tubulin binding	GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0035914//skeletal muscle cell differentiation;GO:0046827//positive regulation of protein export from nucleus;GO:0048147//negative regulation of fibroblast proliferation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0071363//cellular response to growth factor stimulus;GO:0071763//nuclear membrane organization;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000102125	6.265	6.202	7.013	7.304	6.373	9.784	190	213	154	159	197	223	TAFAZZIN	"tafazzin, phospholipid-lysophospholipid transacylase [Source:HGNC Symbol;Acc:HGNC:11577]"	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K13511	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity	GO:0000423//mitophagy;GO:0003007//heart morphogenesis;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006936//muscle contraction;GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization;GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0030097//hemopoiesis;GO:0032048//cardiolipin metabolic process;GO:0032049//cardiolipin biosynthetic process;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0035965//cardiolipin acyl-chain remodeling;GO:0042407//cristae formation;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0048137//spermatocyte division;GO:0048738//cardiac muscle tissue development;GO:0060048//cardiac muscle contraction;GO:1900210//positive regulation of cardiolipin metabolic process;GO:2001171//positive regulation of ATP biosynthetic process	--
ENSG00000102128	0	0	0	0	0	0	0	0	0	0	0	0	RAB40AL	RAB40A like [Source:HGNC Symbol;Acc:HGNC:25410]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0072659//protein localization to plasma membrane	--
ENSG00000102144	78.543	78.132	78.569	83.823	80.673	80.965	4738	4776	3511	3758	4155.45	3611	PGK1	phosphoglycerate kinase 1 [Source:HGNC Symbol;Acc:HGNC:8896]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K00927;K00927;K00927;K00927;K00927	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004618//phosphoglycerate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043531//ADP binding;GO:0047134//protein-disulfide reductase (NAD(P)) activity	GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0030855//epithelial cell differentiation;GO:0031639//plasminogen activation;GO:0071456//cellular response to hypoxia	--
ENSG00000102145	0	0	0	0	0	0	0	0	0	0	0	0	GATA1	GATA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4170]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0017053//transcription repressor complex;GO:0032993//protein-DNA complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070742//C2H2 zinc finger domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007596//blood coagulation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009653//anatomical structure morphogenesis;GO:0010559//regulation of glycoprotein biosynthetic process;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0010725//regulation of primitive erythrocyte differentiation;GO:0030099//myeloid cell differentiation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0030220//platelet formation;GO:0030221//basophil differentiation;GO:0030222//eosinophil differentiation;GO:0030502//negative regulation of bone mineralization;GO:0031100//animal organ regeneration;GO:0033690//positive regulation of osteoblast proliferation;GO:0035162//embryonic hemopoiesis;GO:0035854//eosinophil fate commitment;GO:0043066//negative regulation of apoptotic process;GO:0043306//positive regulation of mast cell degranulation;GO:0045165//cell fate commitment;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0048513//animal organ development;GO:0048821//erythrocyte development;GO:0048873//homeostasis of number of cells within a tissue;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060009//Sertoli cell development;GO:0070527//platelet aggregation;GO:0071222//cellular response to lipopolysaccharide;GO:0071320//cellular response to cAMP;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0097028//dendritic cell differentiation;GO:0097067//cellular response to thyroid hormone stimulus;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	zf-GATA
ENSG00000102158	22.892	24.48	20.948	21.044	21.709	22.227	1753	1877	1173	1227	1371	1247	MAGT1	magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28880]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane	GO:0015095//magnesium ion transmembrane transporter activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0015693//magnesium ion transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0050890//cognition;GO:0055085//transmembrane transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000102172	43.027	41.024	41.909	39.25	35.338	36.332	1507	1451	1088	1019	1043	926	SMS	spermine synthase [Source:HGNC Symbol;Acc:HGNC:11123]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism	K00802;K00802;K00802;K00802	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0016740//transferase activity;GO:0016768//spermine synthase activity	GO:0006555//methionine metabolic process;GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0006597//spermine biosynthetic process;GO:0008215//spermine metabolic process	--
ENSG00000102174	0.023	0.048	0	0	0.164	0	1	3	0	0	5	0	PHEX	phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0007267//cell-cell signaling;GO:0016485//protein processing;GO:0019637//organophosphate metabolic process;GO:0030282//bone mineralization;GO:0030324//lung development;GO:0031214//biomineral tissue development;GO:0033280//response to vitamin D;GO:0042476//odontogenesis;GO:0060348//bone development;GO:0060416//response to growth hormone;GO:0071305//cellular response to vitamin D;GO:0071374//cellular response to parathyroid hormone stimulus;GO:1904383//response to sodium phosphate;GO:1990418//response to insulin-like growth factor stimulus	--
ENSG00000102178	16.55	16.217	17.785	18.252	17.151	20.433	789	770	634	648	695	713	UBL4A	ubiquitin like 4A [Source:HGNC Symbol;Acc:HGNC:12505]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0071818//BAT3 complex	GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0051087//chaperone binding	GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0031647//regulation of protein stability;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000102181	29.752	33.947	32.741	36.413	38.345	33.901	2146	2358	1676	1977	2072	1660	CD99L2	CD99 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:18237]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06520;K06520	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0050904//diapedesis;GO:2000391//positive regulation of neutrophil extravasation;GO:2000409//positive regulation of T cell extravasation	--
ENSG00000102189	1.696	0.951	0.464	0.471	0.552	0.586	153	98	70	57	93	87	EEA1	early endosome antigen 1 [Source:HGNC Symbol;Acc:HGNC:3185]	Cellular Processes;Human Diseases;Cellular Processes	Transport and catabolism;Infectious disease: bacterial;Transport and catabolism	ko04144//Endocytosis;ko05152//Tuberculosis;ko04145//Phagosome	K12478;K12478;K12478	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005969//serine-pyruvate aminotransferase complex;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0044308//axonal spine;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005545//1-phosphatidylinositol binding;GO:0008270//zinc ion binding;GO:0030742//GTP-dependent protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0006906//vesicle fusion;GO:0016189//synaptic vesicle to endosome fusion;GO:0039694//viral RNA genome replication;GO:0045022//early endosome to late endosome transport	--
ENSG00000102195	0	0	0	0	0	0	0	0	0	0	0	0	GPR50	G protein-coupled receptor 50 [Source:HGNC Symbol;Acc:HGNC:4506]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04287	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008502//melatonin receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling	--
ENSG00000102218	4.209	3.643	4.128	3.747	2.977	3.546	323	281	234	213	193	198	RP2	RP2 activator of ARL3 GTPase [Source:HGNC Symbol;Acc:HGNC:10274]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:1990075//periciliary membrane compartment	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007601//visual perception;GO:0015031//protein transport;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0060271//cilium assembly	--
ENSG00000102221	3.012	3.584	2.89	2.157	2.967	2.777	300	296	219	159	219	177	JADE3	jade family PHD finger 3 [Source:HGNC Symbol;Acc:HGNC:22982]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016570//histone modification;GO:0016573//histone acetylation;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0051726//regulation of cell cycle;GO:2000278//regulation of DNA biosynthetic process"	--
ENSG00000102225	88.493	99.764	94.527	100.398	96.83	88.023	3828	4246	2965	3218	3492	2857	CDK16	cyclin dependent kinase 16 [Source:HGNC Symbol;Acc:HGNC:8749]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030133//transport vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006887//exocytosis;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0030252//growth hormone secretion;GO:0031175//neuron projection development;GO:0051726//regulation of cell cycle;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000102226	59.718	65.169	68.876	75.837	73.784	64.738	3852	4215	3309	3532	3952	3045	USP11	ubiquitin specific peptidase 11 [Source:HGNC Symbol;Acc:HGNC:12609]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0001222//transcription corepressor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000102230	6.166	5.529	6.47	6.452	6.789	6.596	598	603	511	513	584	525	PCYT1B	"phosphate cytidylyltransferase 1B, choline [Source:HGNC Symbol;Acc:HGNC:8755]"	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K00968;K00968;K00968;K00968	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane	GO:0003824//catalytic activity;GO:0004105//choline-phosphate cytidylyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0031210//phosphatidylcholine binding	GO:0001541//ovarian follicle development;GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0007283//spermatogenesis;GO:0008654//phospholipid biosynthetic process;GO:0009058//biosynthetic process	--
ENSG00000102239	0	0	0	0	0	0	0	0	0	0	0	0	BRS3	bombesin receptor subtype 3 [Source:HGNC Symbol;Acc:HGNC:1113]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04170	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0004930//G protein-coupled receptor activity;GO:0004946//bombesin receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0008343//adult feeding behavior;GO:0031989//bombesin receptor signaling pathway	--
ENSG00000102241	37.358	31.208	31.67	25.114	28.738	27.565	1646	1418	1008	858	1113	936	HTATSF1	HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Acc:HGNC:5276]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019079//viral genome replication;GO:0032784//regulation of DNA-templated transcription, elongation"	--
ENSG00000102243	0	0	0	0	0	0	0	0	0	0	0	0	VGLL1	vestigial like family member 1 [Source:HGNC Symbol;Acc:HGNC:20985]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000102245	0	0	0	0	0	0	0	0	0	0	0	0	CD40LG	CD40 ligand [Source:HGNC Symbol;Acc:HGNC:11935]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signaling molecules and interaction;Cardiovascular disease;Immune disease;Signal transduction;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Immune disease;Immune disease;Infectious disease: parasitic	ko04060//Cytokine-cytokine receptor interaction;ko05417//Lipid and atherosclerosis;ko05322//Systemic lupus erythematosus;ko04064//NF-kappa B signaling pathway;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05310//Asthma;ko05144//Malaria	K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161;K03161	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005174//CD40 receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0002637//regulation of immunoglobulin production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007159//leukocyte cell-cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0023035//CD40 signaling pathway;GO:0030168//platelet activation;GO:0030183//B cell differentiation;GO:0031295//T cell costimulation;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032753//positive regulation of interleukin-4 production;GO:0042100//B cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045190//isotype switching;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000102265	85.896	97.059	95.811	90.034	86.162	80.947	1402	1587	1159	1096	1185	965	TIMP1	TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820]	Environmental Information Processing	Signal transduction	ko04066//HIF-1 signaling pathway	K16451	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0004857//enzyme inhibitor activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008270//zinc ion binding;GO:0030414//peptidase inhibitor activity;GO:0046872//metal ion binding	GO:0001775//cell activation;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0007165//signal transduction;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0034097//response to cytokine;GO:0042060//wound healing;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043434//response to peptide hormone;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0051216//cartilage development;GO:0071492//cellular response to UV-A;GO:1901164//negative regulation of trophoblast cell migration;GO:1905049//negative regulation of metallopeptidase activity;GO:2001044//regulation of integrin-mediated signaling pathway	--
ENSG00000102271	1.438	0.863	0.46	0.74	0.635	0.61	111	81	32	35	37	40	KLHL4	kelch like family member 4 [Source:HGNC Symbol;Acc:HGNC:6355]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0034451//centriolar satellite	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000102287	2.637	1.602	2.183	3.378	3.369	4.225	126	85	97	153	168	182	GABRE	gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05185;K05185;K05185;K05185;K05185	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport;GO:2001226//negative regulation of chloride transport"	--
ENSG00000102290	0	0.012	0	0.016	0	0	0	1	0	1	0	0	PCDH11X	protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000102302	8.646	8.24	7.808	8.016	9.056	7.242	778.85	746.08	519.51	534.88	689.2	474.7	FGD1	"FYVE, RhoGEF and PH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3663]"	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05720	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0008360//regulation of cell shape;GO:0009887//animal organ morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000102309	3.884	4.148	3.999	3.854	3.498	3.583	101	106	76	73	77	67	PIN4	"peptidylprolyl cis/trans isomerase, NIMA-interacting 4 [Source:HGNC Symbol;Acc:HGNC:8992]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030684//preribosome	GO:0003677//DNA binding;GO:0003681//bent DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006364//rRNA processing	--
ENSG00000102312	6.511	6.536	8.65	7.954	7.699	5.758	220	225	204	197	209	150	PORCN	porcupine O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:17652]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K00181	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032281//AMPA glutamate receptor complex;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0017147//Wnt-protein binding;GO:1990698//palmitoleoyltransferase activity	GO:0006497//protein lipidation;GO:0009100//glycoprotein metabolic process;GO:0016055//Wnt signaling pathway;GO:0018345//protein palmitoylation;GO:0030258//lipid modification;GO:0045234//protein palmitoleylation;GO:0060070//canonical Wnt signaling pathway;GO:0061355//Wnt protein secretion;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels	--
ENSG00000102313	0	0	0	0	0	0	0	0	0	0	0	0	ITIH6	inter-alpha-trypsin inhibitor heavy chain family member 6 [Source:HGNC Symbol;Acc:HGNC:28907]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process	--
ENSG00000102316	146.116	160.172	157.892	149.964	139.507	136.04	6198	6837	4960	4693	5005	4206	MAGED2	MAGE family member D2 [Source:HGNC Symbol;Acc:HGNC:16353]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007565//female pregnancy;GO:0070294//renal sodium ion absorption	--
ENSG00000102317	40.467	42.833	38.444	46.08	39.738	34.023	1719	1879	1313	1499	1568	1134	RBM3	RNA binding motif protein 3 [Source:HGNC Symbol;Acc:HGNC:9900]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0015934//large ribosomal subunit;GO:0030425//dendrite;GO:0042995//cell projection	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035368//selenocysteine insertion sequence binding;GO:0043023//ribosomal large subunit binding	"GO:0006396//RNA processing;GO:0006417//regulation of translation;GO:0045727//positive regulation of translation;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000102349	1.519	1.716	1.479	1.804	1.021	1.054	173	147	105	99	105	91	KLF8	Kruppel like factor 8 [Source:HGNC Symbol;Acc:HGNC:6351]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000102359	0.017	0	0.025	0.209	0.136	0	2.3	0	2.58	3	3.19	0	SRPX2	sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0030054//cell junction;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0062023//collagen-containing extracellular matrix;GO:0097060//synaptic membrane	GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0036458//hepatocyte growth factor binding;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0042325//regulation of phosphorylation;GO:0048870//cell motility;GO:0051965//positive regulation of synapse assembly;GO:0071625//vocalization behavior;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0098609//cell-cell adhesion	--
ENSG00000102362	0.577	0.644	0.615	0.584	0.744	0.79	46.7	52	29.42	34	43.81	41	SYTL4	synaptotagmin like 4 [Source:HGNC Symbol;Acc:HGNC:15588]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0031092//platelet alpha granule membrane;GO:0031410//cytoplasmic vesicle;GO:0070382//exocytic vesicle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0031267//small GTPase binding;GO:0042043//neurexin family protein binding;GO:0046872//metal ion binding	GO:0001778//plasma membrane repair;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0032418//lysosome localization;GO:0045921//positive regulation of exocytosis;GO:0046676//negative regulation of insulin secretion;GO:0050714//positive regulation of protein secretion;GO:0071985//multivesicular body sorting pathway;GO:1905684//regulation of plasma membrane repair	--
ENSG00000102383	2.855	2.71	2.601	2.268	2.255	2.076	335	320	226	199	225	177	ZDHHC15	zinc finger DHHC-type palmitoyltransferase 15 [Source:HGNC Symbol;Acc:HGNC:20342]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030173//integral component of Golgi membrane;GO:0045202//synapse;GO:0098794//postsynapse	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0046872//metal ion binding;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0016188//synaptic vesicle maturation;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0045184//establishment of protein localization;GO:0061001//regulation of dendritic spine morphogenesis;GO:0062237//protein localization to postsynapse;GO:0072657//protein localization to membrane;GO:0140450//protein targeting to Golgi apparatus;GO:1900006//positive regulation of dendrite development	--
ENSG00000102384	0.921	1.232	0.829	0.281	0.475	0.329	50	63	41	16	30	18	CENPI	centromere protein I [Source:HGNC Symbol;Acc:HGNC:3968]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body"	GO:0005515//protein binding	GO:0007548//sex differentiation;GO:0034508//centromere complex assembly	--
ENSG00000102385	0	0	0	0.029	0.025	0	0	0	0	3	3	0	DRP2	dystrophin related protein 2 [Source:HGNC Symbol;Acc:HGNC:3032]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007417//central nervous system development;GO:0050808//synapse organization;GO:0099536//synaptic signaling	--
ENSG00000102387	0	0.046	0	0.062	0.054	0	0	2	0	2	2	0	TAF7L	TATA-box binding protein associated factor 7 like [Source:HGNC Symbol;Acc:HGNC:11548]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03132	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:0051123//RNA polymerase II preinitiation complex assembly	--
ENSG00000102390	8.575	8.375	8.571	8.011	7.129	8.025	207	204	155	144	147	139	PBDC1	polysaccharide biosynthesis domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28790]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000102393	13.003	13.317	11.822	12.407	12.003	15.737	353	363	235	249	273	309	GLA	galactosidase alpha [Source:HGNC Symbol;Acc:HGNC:4296]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism;Lipid metabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00561//Glycerolipid metabolism;ko00600//Sphingolipid metabolism;ko00052//Galactose metabolism;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K01189;K01189;K01189;K01189;K01189;K01189	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004557//alpha-galactosidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0017041//galactosylgalactosylglucosylceramidase activity;GO:0042803//protein homodimerization activity;GO:0052692//raffinose alpha-galactosidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016139//glycoside catabolic process;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0046477//glycosylceramide catabolic process;GO:0046479//glycosphingolipid catabolic process;GO:0051001//negative regulation of nitric-oxide synthase activity	--
ENSG00000102401	30.03	26.025	27.883	23.969	24.972	28.385	1919	1687	1323	1117	1352	1320	ARMCX3	armadillo repeat containing X-linked 3 [Source:HGNC Symbol;Acc:HGNC:24065]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0019896//axonal transport of mitochondrion;GO:0034613//cellular protein localization;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000102409	50.401	52.12	47.948	50.042	48.511	51.763	1363	1405	958	1003	1105	1012	BEX4	brain expressed X-linked 4 [Source:HGNC Symbol;Acc:HGNC:25475]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043014//alpha-tubulin binding	GO:0007059//chromosome segregation;GO:0030334//regulation of cell migration;GO:0042127//regulation of cell population proliferation;GO:1904428//negative regulation of tubulin deacetylation	--
ENSG00000102445	0.643	1.425	1.617	1.287	1.411	1.626	38	65	63	59	53	61	RUBCNL	rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0006629//lipid metabolic process;GO:0006914//autophagy;GO:0019216//regulation of lipid metabolic process;GO:0061909//autophagosome-lysosome fusion;GO:0061910//autophagosome-endosome fusion;GO:0070873//regulation of glycogen metabolic process;GO:0097352//autophagosome maturation	--
ENSG00000102452	15.832	13.314	13.03	11.082	12.428	14.285	1793	1630	1133	1016	1281	1228	NALCN	"sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0022840//leak channel activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0060075//regulation of resting membrane potential;GO:0070588//calcium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000102466	0.138	0.052	0.095	0.152	0.11	0.093	37	14	19	30	24.85	18	FGF14	fibroblast growth factor 14 [Source:HGNC Symbol;Acc:HGNC:3671]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K23920	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0017080//sodium channel regulator activity	GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:1905150//regulation of voltage-gated sodium channel activity	--
ENSG00000102468	0.241	0.654	0.193	0.403	1.089	0.562	26	26	16	12	22	22	HTR2A	5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system;Cellular community - eukaryotes	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04726//Serotonergic synapse;ko04750//Inflammatory mediator regulation of TRP channels;ko04540//Gap junction	K04157;K04157;K04157;K04157;K04157	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0070852//cell body fiber;GO:0098666//G protein-coupled serotonin receptor complex;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	"GO:0001587//Gq/11-coupled serotonin receptor activity;GO:0001618//virus receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0051378//serotonin binding;GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding"	"GO:0001659//temperature homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007568//aging;GO:0007610//behavior;GO:0007613//memory;GO:0008219//cell death;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0014059//regulation of dopamine secretion;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014824//artery smooth muscle contraction;GO:0014832//urinary bladder smooth muscle contraction;GO:0019233//sensory perception of pain;GO:0030431//sleep;GO:0033674//positive regulation of kinase activity;GO:0043267//negative regulation of potassium ion transport;GO:0043406//positive regulation of MAP kinase activity;GO:0044380//protein localization to cytoskeleton;GO:0045600//positive regulation of fat cell differentiation;GO:0045821//positive regulation of glycolytic process;GO:0045907//positive regulation of vasoconstriction;GO:0046718//viral entry into host cell;GO:0048148//behavioral response to cocaine;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0098664//G protein-coupled serotonin receptor signaling pathway;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000102471	11.417	10.326	10.586	11.376	9.715	13.29	774	601	508	535	534	628	NDFIP2	Nedd4 family interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18537]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032585//multivesicular body membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007034//vacuolar transport;GO:0010629//negative regulation of gene expression;GO:0030001//metal ion transport;GO:0031398//positive regulation of protein ubiquitination;GO:0032410//negative regulation of transporter activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051224//negative regulation of protein transport	--
ENSG00000102524	0.454	0.13	0.101	0.076	0.133	0.026	13	7	4	3	6	1	TNFSF13B	TNF superfamily member 13b [Source:HGNC Symbol;Acc:HGNC:11929]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway;ko05323//Rheumatoid arthritis;ko04672//Intestinal immune network for IgA production	K05476;K05476;K05476;K05476	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0001782//B cell homeostasis;GO:0002376//immune system process;GO:0002636//positive regulation of germinal center formation;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030183//B cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0031295//T cell costimulation;GO:0031296//B cell costimulation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0050776//regulation of immune response	--
ENSG00000102531	24.732	19.351	16.06	13.749	15.159	17.226	3047	2400	1456	1261	1572	1554	FNDC3A	fibronectin type III domain containing 3A [Source:HGNC Symbol;Acc:HGNC:20296]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007286//spermatid development;GO:0009566//fertilization;GO:0060009//Sertoli cell development;GO:0098609//cell-cell adhesion	--
ENSG00000102539	0	0	0	0	0	0.053	0	0	0	0	0	1	MLNR	motilin receptor [Source:HGNC Symbol;Acc:HGNC:4495]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05266	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0042562//hormone binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000102543	3.603	2.451	4.724	2.552	2.805	3.289	154	140	126	108	118	115	CDADC1	cytidine and dCMP deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20299]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity;GO:0061676//importin-alpha family protein binding	GO:0009972//cytidine deamination;GO:0070383//DNA cytosine deamination	--
ENSG00000102547	11.619	9.626	13.532	9.963	9.203	16.279	798	588	665	482	573	823	CAB39L	calcium binding protein 39 like [Source:HGNC Symbol;Acc:HGNC:20290]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04150//mTOR signaling pathway;ko04152//AMPK signaling pathway	K08272;K08272	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1902554//serine/threonine protein kinase complex	GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000102554	8.796	7.362	8.942	10.009	8.758	10.526	611	514	452	515	514	532	KLF5	Kruppel like factor 5 [Source:HGNC Symbol;Acc:HGNC:6349]	Human Diseases	Cancer: overview	ko05207//Chemical carcinogenesis - receptor activation	K09206	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043426//MRF binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0014816//skeletal muscle satellite cell differentiation;GO:0014901//satellite cell activation involved in skeletal muscle regeneration;GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0030033//microvillus assembly;GO:0032534//regulation of microvillus assembly;GO:0035914//skeletal muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0045600//positive regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060576//intestinal epithelial cell development;GO:0061586//positive regulation of transcription by transcription factor localization;GO:0099156//cell-cell signaling via exosome;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1990830//cellular response to leukemia inhibitory factor"	zf-C2H2
ENSG00000102572	241.414	239.535	236.031	280.584	264.843	272.642	13410.85	13357.47	9675.98	11395.74	12399	10919.16	STK24	serine/threonine kinase 24 [Source:HGNC Symbol;Acc:HGNC:11403]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0009267//cellular response to starvation;GO:0016310//phosphorylation;GO:0030336//negative regulation of cell migration;GO:0042542//response to hydrogen peroxide;GO:0046777//protein autophosphorylation;GO:0048679//regulation of axon regeneration;GO:0048680//positive regulation of axon regeneration;GO:0097194//execution phase of apoptosis	--
ENSG00000102575	34.345	38.063	39.661	41.944	39.601	44.648	1143	1299	987	1070	1124	1074	ACP5	"acid phosphatase 5, tartrate resistant [Source:HGNC Symbol;Acc:HGNC:124]"	Metabolism;Human Diseases;Cellular Processes;Organismal Systems;Metabolism	Global and overview maps;Immune disease;Transport and catabolism;Development and regeneration;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05323//Rheumatoid arthritis;ko04142//Lysosome;ko04380//Osteoclast differentiation;ko00740//Riboflavin metabolism	K14379;K14379;K14379;K14379;K14379	GO:0005764//lysosome;GO:0005829//cytosol;GO:0016021//integral component of membrane	GO:0003993//acid phosphatase activity;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation;GO:0032496//response to lipopolysaccharide;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032695//negative regulation of interleukin-12 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032929//negative regulation of superoxide anion generation;GO:0034097//response to cytokine;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045453//bone resorption;GO:0050728//negative regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0060349//bone morphogenesis	--
ENSG00000102580	53.11	47.05	35.626	31.78	38.914	32.099	6158	5408	3038	2714	3812	2708	DNAJC3	DnaJ heat shock protein family (Hsp40) member C3 [Source:HGNC Symbol;Acc:HGNC:9439]	Human Diseases;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation"	ko05164//Influenza A;ko04141//Protein processing in endoplasmic reticulum	K09523;K09523	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005790//smooth endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding	GO:0006417//regulation of translation;GO:0006986//response to unfolded protein;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0036494//positive regulation of translation initiation in response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0051607//defense response to virus;GO:0070417//cellular response to cold;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	--
ENSG00000102595	6.54	5.652	6.262	4.562	4.517	5.71	581	420	318	209	285	307	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:15664]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K11718	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0032991//protein-containing complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0003980//UDP-glucose:glycoprotein glucosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0051082//unfolded protein binding	GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0071712//ER-associated misfolded protein catabolic process;GO:0097359//UDP-glucosylation;GO:1904380//endoplasmic reticulum mannose trimming	--
ENSG00000102606	22.98	20.851	20.583	18.561	21.422	21.263	1667	1565	1076	973	1233	1147	ARHGEF7	Rho guanine nucleotide exchange factor 7 [Source:HGNC Symbol;Acc:HGNC:15607]	Cellular Processes;Human Diseases	Cell motility;Infectious disease: bacterial	ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection	K13710;K13710	GO:0000322//storage vacuole;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0097431//mitotic spindle pole;GO:0098794//postsynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043015//gamma-tubulin binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010763//positive regulation of fibroblast migration;GO:0030032//lamellipodium assembly;GO:0032092//positive regulation of protein binding;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0048041//focal adhesion assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060124//positive regulation of growth hormone secretion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1904424//regulation of GTP binding;GO:1905833//negative regulation of microtubule nucleation;GO:2000394//positive regulation of lamellipodium morphogenesis	--
ENSG00000102678	0	0.074	0	0	0	0	0	7	0	0	0	0	FGF9	fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001649//osteoblast differentiation;GO:0001654//eye development;GO:0001934//positive regulation of protein phosphorylation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002062//chondrocyte differentiation;GO:0006606//protein import into nucleus;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008584//male gonad development;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0021762//substantia nigra development;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030238//male sex determination;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030334//regulation of cell migration;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0042472//inner ear morphogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048505//regulation of timing of cell differentiation;GO:0048566//embryonic digestive tract development;GO:0048706//embryonic skeletal system development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051781//positive regulation of cell division;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060484//lung-associated mesenchyme development;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1905931//negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	--
ENSG00000102683	3.025	3.069	2.744	3.716	2.864	3.284	100	102	67	91	80	79	SGCG	sarcoglycan gamma [Source:HGNC Symbol;Acc:HGNC:10809]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12564;K12564;K12564;K12564	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016011//dystroglycan complex;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0007517//muscle organ development;GO:0048738//cardiac muscle tissue development;GO:0060047//heart contraction	--
ENSG00000102699	18.444	15.809	15.284	13.826	15.492	14.624	2080	1792	1273	1155	1476	1200	PARP4	poly(ADP-ribose) polymerase family member 4 [Source:HGNC Symbol;Acc:HGNC:271]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04210//Apoptosis;ko03410//Base excision repair	K10798;K10798	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:1990404//protein ADP-ribosylase activity	GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006471//protein ADP-ribosylation;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0008219//cell death;GO:0009410//response to xenobiotic stimulus;GO:0051972//regulation of telomerase activity;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000102710	10.152	7.969	8.447	6.645	8.285	10.02	609.15	474.42	378.67	300.33	409.05	438.82	SUPT20H	"SPT20 homolog, SAGA complex component [Source:HGNC Symbol;Acc:HGNC:20596]"	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21245	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0070461//SAGA-type complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	"GO:0006282//regulation of DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006914//autophagy;GO:0007369//gastrulation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000102738	5.71	5.197	5.184	5.344	4.339	6.778	176	161	118	122	113	152	MRPS31	mitochondrial ribosomal protein S31 [Source:HGNC Symbol;Acc:HGNC:16632]	-	-	-	-	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0032543//mitochondrial translation	--
ENSG00000102743	2.271	2.021	2.323	2.759	2.36	2.387	180	161	136	162	158	113	SLC25A15	solute carrier family 25 member 15 [Source:HGNC Symbol;Acc:HGNC:10985]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000064//L-ornithine transmembrane transporter activity	GO:0000050//urea cycle;GO:1990575//mitochondrial L-ornithine transmembrane transport	--
ENSG00000102753	13.44	11.133	11.225	8.292	8.353	9.291	1177	980	726	524	618	592	KPNA3	karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396]	Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Cancer: overview;Translation	ko05132//Salmonella infection;ko05207//Chemical carcinogenesis - receptor activation;ko03013//Nucleocytoplasmic transport	K23583;K23583;K23583	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042564//NLS-dependent protein nuclear import complex;GO:0043657//host cell	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0015031//protein transport;GO:0016032//viral process;GO:0046718//viral entry into host cell;GO:0065003//protein-containing complex assembly;GO:0075732//viral penetration into host nucleus	--
ENSG00000102755	0.038	0	0	0	0.009	0	1	0	0	0	1	0	FLT1	fms related receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune disease;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko05323//Rheumatoid arthritis;ko04066//HIF-1 signaling pathway	K05096;K05096;K05096;K05096;K05096;K05096;K05096;K05096;K05096	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0036332//placental growth factor-activated receptor activity	GO:0001525//angiogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0031401//positive regulation of protein modification process;GO:0033674//positive regulation of kinase activity;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036323//vascular endothelial growth factor receptor-1 signaling pathway;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045766//positive regulation of angiogenesis;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0048598//embryonic morphogenesis;GO:1905563//negative regulation of vascular endothelial cell proliferation;GO:1990384//hyaloid vascular plexus regression	--
ENSG00000102760	0.705	0.801	0.613	0.815	1.608	0.484	14	16	9	12	27	7	RGCC	regulator of cell cycle [Source:HGNC Symbol;Acc:HGNC:20369]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0070412//R-SMAD binding	GO:0001100//negative regulation of exit from mitosis;GO:0001818//negative regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0001937//negative regulation of endothelial cell proliferation;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0006956//complement activation;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016525//negative regulation of angiogenesis;GO:0032147//activation of protein kinase activity;GO:0032967//positive regulation of collagen biosynthetic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051496//positive regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0071456//cellular response to hypoxia;GO:0072537//fibroblast activation;GO:0090272//negative regulation of fibroblast growth factor production;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1901203//positive regulation of extracellular matrix assembly;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000102763	7.087	5.841	5.851	5.437	5.879	6.704	1041	840	643	556	694	705	VWA8	von Willebrand factor A domain containing 8 [Source:HGNC Symbol;Acc:HGNC:29071]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000102780	0.551	0.535	0.351	0.385	0.323	0.471	163	94	54	66	94.01	86	DGKH	diacylglycerol kinase eta [Source:HGNC Symbol;Acc:HGNC:2854]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0032093//SAM domain binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0046339//diacylglycerol metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation	--
ENSG00000102781	3.924	4.058	3.857	3.03	3.407	4.088	463	420	285	221	308	327	KATNAL1	katanin catalytic subunit A1 like 1 [Source:HGNC Symbol;Acc:HGNC:28361]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008568//microtubule-severing ATPase activity;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0051013//microtubule severing;GO:0051301//cell division	--
ENSG00000102786	50.944	41.415	32.112	50.197	53.335	60.601	7512.69	6136.21	3504.55	5464.31	6635.2	6487.26	INTS6	integrator complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:14879]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton;GO:0032039//integrator complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing	--
ENSG00000102794	0	0	0	0	0	0	0	0	0	0	0	0	ACOD1	aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00660//C5-Branched dibasic acid metabolism	K17724;K17724	GO:0005739//mitochondrion	GO:0016829//lyase activity;GO:0047613//aconitate decarboxylase activity	GO:0002376//immune system process;GO:0002760//positive regulation of antimicrobial humoral response;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007566//embryo implantation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032480//negative regulation of type I interferon production;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0035458//cellular response to interferon-beta;GO:0045087//innate immune response;GO:0045824//negative regulation of innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0051607//defense response to virus;GO:0071219//cellular response to molecule of bacterial origin;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071393//cellular response to progesterone stimulus;GO:0072573//tolerance induction to lipopolysaccharide;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000102796	5.552	6.172	5.978	5.59	5.451	4.357	133	141	105	92	116	80	DHRS12	dehydrogenase/reductase 12 [Source:HGNC Symbol;Acc:HGNC:25832]	-	-	-	-	-	GO:0016491//oxidoreductase activity	-	--
ENSG00000102802	1.744	1.359	1.167	0.567	0.622	0.578	83	65	41	20	25	20	MEDAG	mesenteric estrogen dependent adipogenesis [Source:HGNC Symbol;Acc:HGNC:25926]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0045600//positive regulation of fat cell differentiation	--
ENSG00000102804	54.656	60.013	56.377	59.609	57.076	62.465	4817	5250	3603	3618	4005	3729	TSC22D1	TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II	TSC22
ENSG00000102805	28.649	27.399	28.92	27.58	26.479	27.76	1579.37	1486.93	1160	1099	1235.82	1107.79	CLN5	CLN5 intracellular trafficking protein [Source:HGNC Symbol;Acc:HGNC:2076]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12390	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0005537//mannose binding;GO:0016798//hydrolase activity, acting on glycosyl bonds"	"GO:0006465//signal peptide processing;GO:0007040//lysosome organization;GO:0007042//lysosomal lumen acidification;GO:0007420//brain development;GO:0022008//neurogenesis;GO:0030163//protein catabolic process;GO:0042147//retrograde transport, endosome to Golgi;GO:0042551//neuron maturation;GO:0070085//glycosylation;GO:1904426//positive regulation of GTP binding"	--
ENSG00000102837	0.407	0.472	0.276	0.16	0.422	0.326	24	28	12	7	21	14	OLFM4	olfactomedin 4 [Source:HGNC Symbol;Acc:HGNC:17190]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex;GO:0035580//specific granule lumen;GO:0042581//specific granule;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0003824//catalytic activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000102854	0.865	0.63	0.883	2.466	1.66	1.809	25	29	24	56	64	60	MSLN	mesothelin [Source:HGNC Symbol;Acc:HGNC:7371]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0031016//pancreas development	--
ENSG00000102858	28.279	29.483	30.565	33.888	33.017	32.464	1615	1684	1313	1295	1566	1263	MGRN1	mahogunin ring finger 1 [Source:HGNC Symbol;Acc:HGNC:20254]	Genetic Information Processing;Environmental Information Processing	"Folding, sorting and degradation;Signal transduction"	ko04120//Ubiquitin mediated proteolysis;ko04340//Hedgehog signaling pathway	K10604;K10604	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006513//protein monoubiquitination;GO:0008333//endosome to lysosome transport;GO:0016567//protein ubiquitination;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0045879//negative regulation of smoothened signaling pathway	--
ENSG00000102870	10.367	10.716	11.729	11.213	11.21	11.786	1308	1359	1093	1048	1195	1082	ZNF629	zinc finger protein 629 [Source:HGNC Symbol;Acc:HGNC:29008]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000102871	4.994	4.806	5.634	5.114	6.062	5.63	155	150	128	117	158	126	TRADD	TNFRSF1A associated via death domain [Source:HGNC Symbol;Acc:HGNC:12030]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Signal transduction;Immune system;Immune system;Endocrine system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04071//Sphingolipid signaling pathway;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04920//Adipocytokine signaling pathway	K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171;K03171	GO:0002947//tumor necrosis factor receptor superfamily complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0031264//death-inducing signaling complex;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0045121//membrane raft	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0060090//molecular adaptor activity;GO:0070513//death domain binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0030335//positive regulation of cell migration;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050729//positive regulation of inflammatory response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051798//positive regulation of hair follicle development;GO:0071356//cellular response to tumor necrosis factor;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000102878	2.46	2.37	3.735	2.5	2.944	4.219	73.42	77	68	59	78.57	94	HSF4	heat shock transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:5227]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0008284//positive regulation of cell population proliferation;GO:0033169//histone H3-K9 demethylation;GO:0043010//camera-type eye development;GO:0045597//positive regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0070306//lens fiber cell differentiation"	HSF
ENSG00000102879	0.416	0.478	0.514	0.361	0.357	0.408	14	12	6	9	10	10	CORO1A	coronin 1A [Source:HGNC Symbol;Acc:HGNC:2252]	Human Diseases;Cellular Processes	Infectious disease: bacterial;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome	K13882;K13882	GO:0001772//immunological synapse;GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030424//axon;GO:0030670//phagocytic vesicle membrane;GO:0030864//cortical actin cytoskeleton;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0032036//myosin heavy chain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0051015//actin filament binding	GO:0001845//phagolysosome assembly;GO:0006816//calcium ion transport;GO:0006909//phagocytosis;GO:0007015//actin filament organization;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0030335//positive regulation of cell migration;GO:0030595//leukocyte chemotaxis;GO:0030833//regulation of actin filament polymerization;GO:0031339//negative regulation of vesicle fusion;GO:0031589//cell-substrate adhesion;GO:0032796//uropod organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0034097//response to cytokine;GO:0038180//nerve growth factor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0043029//T cell homeostasis;GO:0043320//natural killer cell degranulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0045087//innate immune response;GO:0048873//homeostasis of number of cells within a tissue;GO:0050870//positive regulation of T cell activation;GO:0050918//positive chemotaxis;GO:0051126//negative regulation of actin nucleation;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0061502//early endosome to recycling endosome transport;GO:0071353//cellular response to interleukin-4	--
ENSG00000102882	49.264	49.922	51.952	56.561	56.565	63.109	1317	1356	1077	1186	1300	1241	MAPK3	mitogen-activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6877]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Signal transduction;Cancer: overview;Immune system;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Immune system;Nervous system;Cancer: specific types;Circulatory system;Cancer: specific types;Infectious disease: parasitic;Cellular community - eukaryotes;Cell growth and death;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Signal transduction;Nervous system;Nervous system;Nervous system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Cancer: overview;Immune system;Signal transduction;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cellular community - eukaryotes;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Endocrine and metabolic disease;Excretory system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko04360//Axon guidance;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05224//Breast cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04350//TGF-beta signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05133//Pertussis;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko04930//Type II diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371;K04371	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0031143//pseudopodium	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019902//phosphatase binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0007049//cell cycle;GO:0007166//cell surface receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010759//positive regulation of macrophage chemotaxis;GO:0014032//neural crest cell development;GO:0016310//phosphorylation;GO:0019233//sensory perception of pain;GO:0030278//regulation of ossification;GO:0030509//BMP signaling pathway;GO:0030641//regulation of cellular pH;GO:0030878//thyroid gland development;GO:0031281//positive regulation of cyclase activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032496//response to lipopolysaccharide;GO:0032872//regulation of stress-activated MAPK cascade;GO:0033129//positive regulation of histone phosphorylation;GO:0034198//cellular response to amino acid starvation;GO:0034614//cellular response to reactive oxygen species;GO:0035066//positive regulation of histone acetylation;GO:0035556//intracellular signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042473//outer ear morphogenesis;GO:0043330//response to exogenous dsRNA;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048538//thymus development;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051216//cartilage development;GO:0051403//stress-activated MAPK cascade;GO:0051493//regulation of cytoskeleton organization;GO:0051973//positive regulation of telomerase activity;GO:0060020//Bergmann glial cell differentiation;GO:0060324//face development;GO:0060425//lung morphogenesis;GO:0060440//trachea formation;GO:0061308//cardiac neural crest cell development involved in heart development;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070849//response to epidermal growth factor;GO:0071260//cellular response to mechanical stimulus;GO:0071276//cellular response to cadmium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0072584//caveolin-mediated endocytosis;GO:0090170//regulation of Golgi inheritance;GO:0120041//positive regulation of macrophage proliferation;GO:1903351//cellular response to dopamine;GO:1904355//positive regulation of telomere capping;GO:1904417//positive regulation of xenophagy;GO:2000641//regulation of early endosome to late endosome transport;GO:2000657//negative regulation of apolipoprotein binding"	--
ENSG00000102886	0.134	0	0.242	0.121	0.159	0	3	0	4	2	3	0	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28638]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K22387;K22387	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004622//lysophospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0070291//N-acylethanolamine metabolic process	--
ENSG00000102890	0.148	0.154	0.172	0.029	0.023	0.145	7	8	6	1	1	5	ELMO3	engulfment and cell motility 3 [Source:HGNC Symbol;Acc:HGNC:17289]	Human Diseases	Infectious disease: bacterial	ko05100//Bacterial invasion of epithelial cells	K19241	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0007015//actin filament organization;GO:0048870//cell motility	--
ENSG00000102891	0	0	0	0	0	0	0	0	0	0	0	0	MT4	metallothionein 4 [Source:HGNC Symbol;Acc:HGNC:18705]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0046872//metal ion binding	GO:0006875//cellular metal ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0008150//biological_process;GO:0010273//detoxification of copper ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000102893	30.019	28.161	24.803	23.175	26.213	23.411	2212	1924	1358	1290	1511	1274	PHKB	phosphorylase kinase regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:8927]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04910//Insulin signaling pathway;ko04922//Glucagon signaling pathway	K07190;K07190;K07190	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005964//phosphorylase kinase complex;GO:0016020//membrane	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation	--
ENSG00000102897	15.532	16.128	15.907	12.042	13.682	11.83	425	448	305	247	307	249	LYRM1	LYR motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25074]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030496//midbody	-	-	--
ENSG00000102898	34.955	36.96	36.79	36.73	37.276	41.596	1065	1103	810	848	935	882	NUTF2	nuclear transport factor 2 [Source:HGNC Symbol;Acc:HGNC:13722]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0044613//nuclear pore central transport channel;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0090204//protein localization to nuclear pore	--
ENSG00000102900	24.695	22.618	27.176	23.844	27.677	21.008	904	945	698	745	924	648	NUP93	nucleoporin 93 [Source:HGNC Symbol;Acc:HGNC:28958]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14309;K14309	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006998//nuclear envelope organization;GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction	--
ENSG00000102901	7.129	6.993	10.613	8.358	6.976	8.293	281	283	274	269	242	257	CENPT	centromere protein T [Source:HGNC Symbol;Acc:HGNC:25787]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051382//kinetochore assembly	Others
ENSG00000102904	1.505	2.194	2.432	1.419	1.933	1.811	63	87	65	46	62	56	TSNAXIP1	translin associated factor X interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18586]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030154//cell differentiation	--
ENSG00000102908	5.262	3.007	3.715	2.943	3.494	3.681	1204	778	664	537	737	661	NFAT5	nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006970//response to osmotic stress;GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070884//regulation of calcineurin-NFAT signaling cascade;GO:0071345//cellular response to cytokine stimulus;GO:0071474//cellular hyperosmotic response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell"	RHD
ENSG00000102910	35.686	32.948	31.508	28.645	31.832	30.313	3445.65	3382.33	2296.01	2097.05	2671.24	2174.27	LONP2	"lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0004176//ATP-dependent peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding	GO:0006508//proteolysis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0016558//protein import into peroxisome matrix;GO:0030163//protein catabolic process;GO:0031998//regulation of fatty acid beta-oxidation	--
ENSG00000102921	12.251	10.654	9.777	9.739	11.319	9.138	1690	1572	1060	1059	1185	976	N4BP1	NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0043130//ubiquitin binding	GO:0001818//negative regulation of cytokine production;GO:0002376//immune system process;GO:0031397//negative regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034644//cellular response to UV;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000102924	0.134	0.02	0	0	0	0	2	1	0	0	0	0	CBLN1	cerebellin 1 precursor [Source:HGNC Symbol;Acc:HGNC:1543]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0062023//collagen-containing extracellular matrix;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0009306//protein secretion;GO:0021707//cerebellar granule cell differentiation;GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0099151//regulation of postsynaptic density assembly;GO:0099558//maintenance of synapse structure;GO:1900454//positive regulation of long-term synaptic depression;GO:1905606//regulation of presynapse assembly;GO:1905703//negative regulation of inhibitory synapse assembly	--
ENSG00000102931	29.893	28.9	29.403	30.805	29.939	28.908	1220.86	1182.81	881.15	931.91	1033.04	849.02	ARL2BP	ADP ribosylation factor like GTPase 2 binding protein [Source:HGNC Symbol;Acc:HGNC:17146]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030496//midbody;GO:0042995//cell projection;GO:0043227//membrane-bounded organelle	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	"GO:0007165//signal transduction;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity;GO:0051457//maintenance of protein location in nucleus"	--
ENSG00000102934	1.525	2.47	1.91	1.904	2.783	2.147	69.14	98.19	52.85	62.09	86.96	66.98	PLLP	plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043218//compact myelin;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath	GO:0006811//ion transport;GO:0009611//response to wounding;GO:0042552//myelination	--
ENSG00000102935	0.665	0.62	0.77	0.489	0.738	0.562	60	63	52	33	64	35	ZNF423	zinc finger protein 423 [Source:HGNC Symbol;Acc:HGNC:16762]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061512//protein localization to cilium;GO:0120163//negative regulation of cold-induced thermogenesis"	zf-C2H2
ENSG00000102962	0	0	0	0	0	0	0	0	0	0	0	0	CCL22	C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21095;K21095;K21095;K21095	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000102967	2.574	2.568	2.805	2.901	2.276	4.226	114	88	94	86	87	93	DHODH	dihydroorotate dehydrogenase (quinone) [Source:HGNC Symbol;Acc:HGNC:2867]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K00254;K00254	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0004151//dihydroorotase activity;GO:0004152//dihydroorotate dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors"	GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006225//UDP biosynthetic process;GO:0009220//pyrimidine ribonucleotide biosynthetic process;GO:0044205//'de novo' UMP biosynthetic process;GO:0072527//pyrimidine-containing compound metabolic process	--
ENSG00000102970	0	0	0	0	0	0	0	0	0	0	0	0	CCL17	C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway	K21083;K21083;K21083;K21083;K21083	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031729//CCR4 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0045662//negative regulation of myoblast differentiation;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000102974	17.011	16.326	17.344	13.64	14.346	16.986	1332	1277	997	797	954	973	CTCF	CCCTC-binding factor [Source:HGNC Symbol;Acc:HGNC:13723]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus"	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043035//chromatin insulator sequence binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007059//chromosome segregation;GO:0008285//negative regulation of cell population proliferation;GO:0010216//maintenance of DNA methylation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016584//nucleosome positioning;GO:0031060//regulation of histone methylation;GO:0035065//regulation of histone acetylation;GO:0040029//regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0071459//protein localization to chromosome, centromeric region;GO:0071514//genetic imprinting"	zf-C2H2
ENSG00000102977	7.661	8.364	8.288	6.495	9.686	7.313	238	256	187	150	201	166	ACD	ACD shelterin complex subunit and telomerase recruitment factor [Source:HGNC Symbol;Acc:HGNC:25070]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0016604//nuclear body;GO:0070187//shelterin complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0044877//protein-containing complex binding;GO:0070182//DNA polymerase binding	"GO:0000723//telomere maintenance;GO:0001501//skeletal system development;GO:0001655//urogenital system development;GO:0006886//intracellular protein transport;GO:0007004//telomere maintenance via telomerase;GO:0016233//telomere capping;GO:0030326//embryonic limb morphogenesis;GO:0031848//protection from non-homologous end joining at telomere;GO:0032202//telomere assembly;GO:0032206//positive regulation of telomere maintenance;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035282//segmentation;GO:0051973//positive regulation of telomerase activity;GO:0060381//positive regulation of single-stranded telomeric DNA binding;GO:0070198//protein localization to chromosome, telomeric region;GO:0070200//establishment of protein localization to telomere"	--
ENSG00000102978	22.354	23.656	24.608	23.457	21.448	23.664	814	870	665	628	661	630	POLR2C	RNA polymerase II subunit C [Source:HGNC Symbol;Acc:HGNC:9189]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03011;K03011	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000102981	5.074	3.275	5.198	4.914	5.316	4.745	131	85	99	94	116	89	PARD6A	par-6 family cell polarity regulator alpha [Source:HGNC Symbol;Acc:HGNC:15943]	Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Transport and catabolism;Signal transduction;Development and regeneration;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04390//Hippo signaling pathway	K06093;K06093;K06093;K06093;K06093;K06093	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0034451//centriolar satellite;GO:0042995//cell projection;GO:0070160//tight junction;GO:0120157//PAR polarity complex	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding	GO:0001933//negative regulation of protein phosphorylation;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0016032//viral process;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045217//cell-cell junction maintenance;GO:0050714//positive regulation of protein secretion;GO:0051301//cell division;GO:0060341//regulation of cellular localization;GO:1904781//positive regulation of protein localization to centrosome	--
ENSG00000102984	6.055	6.777	5.726	6.381	4.325	5.115	206	228	154	145	135	134	ZNF821	zinc finger protein 821 [Source:HGNC Symbol;Acc:HGNC:28043]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000102996	21.459	24.03	23.334	26.486	28.378	26.279	1808	2035	1452	1653	2020	1611	MMP15	matrix metallopeptidase 15 [Source:HGNC Symbol;Acc:HGNC:7161]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K07995	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0032355//response to estradiol;GO:0035987//endodermal cell differentiation;GO:0050790//regulation of catalytic activity	--
ENSG00000103005	10.518	14.207	11.809	9.751	11.218	8.734	437	506	339	334	412	289	USB1	U6 snRNA biogenesis phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:25792]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045171//intercellular bridge	"GO:0000175//3'-5'-exoribonuclease activity;GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:1990838//poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends"	"GO:0008380//RNA splicing;GO:0034472//snRNA 3'-end processing;GO:0034477//U6 snRNA 3'-end processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000103018	48.565	49.172	48.987	55.452	50.102	47.048	1678	1724	1293	1379	1436	1302	CYB5B	cytochrome b5 type B [Source:HGNC Symbol;Acc:HGNC:24374]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:1903958//nitric-oxide synthase complex	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050421//nitrite reductase (NO-forming) activity	GO:0006805//xenobiotic metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0006979//response to oxidative stress;GO:0050790//regulation of catalytic activity	--
ENSG00000103021	3.265	3.73	2.653	1.42	1.84	1.332	357	410	214	115	170	106	CCDC113	coiled-coil domain containing 113 [Source:HGNC Symbol;Acc:HGNC:25002]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000103023	0	0	0	0	0	0	0	0	0	0	0	0	PRSS54	serine protease 54 [Source:HGNC Symbol;Acc:HGNC:26336]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity	GO:0006508//proteolysis	--
ENSG00000103024	17.211	20.237	22.385	25.835	23.097	19.455	302	361	290	333	344	250	NME3	NME/NM23 nucleoside diphosphate kinase 3 [Source:HGNC Symbol;Acc:HGNC:7851]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006915//apoptotic process;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000103034	5.171	4.34	2.415	6.351	6.476	6.72	293	280	112	275	368	317	NDRG4	NDRG family member 4 [Source:HGNC Symbol;Acc:HGNC:14466]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031253//cell projection membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001947//heart looping;GO:0007165//signal transduction;GO:0007420//brain development;GO:0008542//visual learning;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0010976//positive regulation of neuron projection development;GO:0014912//negative regulation of smooth muscle cell migration;GO:0030154//cell differentiation;GO:0035050//embryonic heart tube development;GO:0048278//vesicle docking;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0060038//cardiac muscle cell proliferation;GO:0060973//cell migration involved in heart development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2001135//regulation of endocytic recycling	--
ENSG00000103035	46.395	52.366	52.337	39.871	45.874	44.153	1456	1612	1166	900	1151	908	PSMD7	"proteasome 26S subunit, non-ATPase 7 [Source:HGNC Symbol;Acc:HGNC:9565]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03038;K03038;K03038;K03038;K03038;K03038;K03038;K03038;K03038	GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0006508//proteolysis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000103037	2.71	2.104	1.851	2.083	2.13	1.933	159.43	126.22	87.74	103.7	118.19	92.4	SETD6	"SET domain containing 6, protein lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:26116]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0051059//NF-kappaB binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0018022//peptidyl-lysine methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0019827//stem cell population maintenance;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0048863//stem cell differentiation;GO:0050727//regulation of inflammatory response	--
ENSG00000103042	6.321	7.661	6.752	6.734	7.058	8.092	520	543	404	342	476	478	SLC38A7	solute carrier family 38 member 7 [Source:HGNC Symbol;Acc:HGNC:25582]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043025//neuronal cell body	GO:0005290//L-histidine transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015182//L-asparagine transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0015191//L-methionine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0006867//asparagine transport;GO:0006868//glutamine transport;GO:0015711//organic anion transport;GO:0015803//branched-chain amino acid transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015808//L-alanine transport;GO:0015813//L-glutamate transmembrane transport;GO:0015821//methionine transport;GO:0015825//L-serine transport;GO:0070778//L-aspartate transmembrane transport;GO:0089709//L-histidine transmembrane transport;GO:0098655//cation transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000103043	23.58	24.85	23.207	27.102	26.646	24.56	1451	1500	1033	1257	1401	1118	VAC14	VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis	K15305;K15305	GO:0000139//Golgi membrane;GO:0000306//extrinsic component of vacuolar membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070772//PAS complex	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0033674//positive regulation of kinase activity	--
ENSG00000103044	0.173	0.286	0.333	0.412	0.381	0.348	15	25	21	21	28	22	HAS3	hyaluronan synthase 3 [Source:HGNC Symbol;Acc:HGNC:4820]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036117//hyaluranon cable	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0050501//hyaluronan synthase activity	"GO:0005975//carbohydrate metabolic process;GO:0030213//hyaluronan biosynthetic process;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0085029//extracellular matrix assembly;GO:1900106//positive regulation of hyaluranon cable assembly"	--
ENSG00000103047	3.912	4.127	4.736	4.642	4.572	4.388	397	421	355	349	392	324	TANGO6	transport and golgi organization 6 homolog [Source:HGNC Symbol;Acc:HGNC:25749]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0009306//protein secretion	--
ENSG00000103051	20.504	17.02	18.925	18.884	21.713	19.695	1155	999	817	819	942	793	COG4	component of oligomeric golgi complex 4 [Source:HGNC Symbol;Acc:HGNC:18620]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0048213//Golgi vesicle prefusion complex stabilization;GO:0070085//glycosylation"	--
ENSG00000103056	4.955	4.993	7.866	9.79	6.806	10.674	530.65	529	548.36	568.89	547.25	736.52	SMPD3	sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K12352;K12352	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001786//phosphatidylserine binding;GO:0003824//catalytic activity;GO:0004620//phospholipase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061751//neutral sphingomyelin phosphodiesterase activity;GO:0070300//phosphatidic acid binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001932//regulation of protein phosphorylation;GO:0001958//endochondral ossification;GO:0002063//chondrocyte development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002685//regulation of leukocyte migration;GO:0003433//chondrocyte development involved in endochondral bone morphogenesis;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0015774//polysaccharide transport;GO:0030072//peptide hormone secretion;GO:0030282//bone mineralization;GO:0030324//lung development;GO:0030509//BMP signaling pathway;GO:0032963//collagen metabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0035264//multicellular organism growth;GO:0043491//protein kinase B signaling;GO:0045840//positive regulation of mitotic nuclear division;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048286//lung alveolus development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051216//cartilage development;GO:0060348//bone development;GO:0060541//respiratory system development;GO:0061035//regulation of cartilage development;GO:0070301//cellular response to hydrogen peroxide;GO:0070314//G1 to G0 transition;GO:0071286//cellular response to magnesium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0071461//cellular response to redox state;GO:0071897//DNA biosynthetic process;GO:0085029//extracellular matrix assembly;GO:0090520//sphingolipid mediated signaling pathway;GO:0097187//dentinogenesis;GO:0098868//bone growth;GO:0140014//mitotic nuclear division;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900125//regulation of hyaluronan biosynthetic process;GO:1900126//negative regulation of hyaluronan biosynthetic process;GO:1901653//cellular response to peptide;GO:1903543//positive regulation of exosomal secretion	--
ENSG00000103061	9.959	8.436	10.837	8.95	8.706	10.082	756.29	713.47	676.98	530.95	613.91	620.53	SLC7A6OS	solute carrier family 7 member 6 opposite strand [Source:HGNC Symbol;Acc:HGNC:25807]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	GO:0002244//hematopoietic progenitor cell differentiation;GO:0015031//protein transport;GO:0032502//developmental process	--
ENSG00000103064	33.212	31.677	35.629	32.718	34.586	47.447	3987.71	3697.53	3222.02	2872.05	3277.09	3748.47	SLC7A6	solute carrier family 7 member 6 [Source:HGNC Symbol;Acc:HGNC:11064]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015297//antiporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015807//L-amino acid transport;GO:0015822//ornithine transport;GO:0055085//transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1990822//basic amino acid transmembrane transport	--
ENSG00000103066	17.04	18.505	19.338	16.37	17.426	19.777	722	835	626	594	716	611	PLA2G15	phospholipase A2 group XV [Source:HGNC Symbol;Acc:HGNC:17163]	Cellular Processes;Metabolism	Transport and catabolism;Lipid metabolism	ko04142//Lysosome;ko00564//Glycerophospholipid metabolism	K06129;K06129	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005543//phospholipid binding;GO:0008270//zinc ion binding;GO:0008374//O-acyltransferase activity;GO:0008970//phospholipase A1 activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047499//calcium-independent phospholipase A2 activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0006658//phosphatidylserine metabolic process;GO:0006672//ceramide metabolic process;GO:0009062//fatty acid catabolic process;GO:0016042//lipid catabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process	--
ENSG00000103067	2.278	2.196	2.208	2.392	2.962	2.014	162	157	116	126	178	101	ESRP2	epithelial splicing regulatory protein 2 [Source:HGNC Symbol;Acc:HGNC:26152]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis"	--
ENSG00000103089	0.284	0.219	0.205	0.595	0.641	0.441	11	11	5	22	27	16	FA2H	fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0080132//fatty acid alpha-hydroxylase activity	GO:0001949//sebaceous gland cell differentiation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0006679//glucosylceramide biosynthetic process;GO:0006682//galactosylceramide biosynthetic process;GO:0008610//lipid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0030258//lipid modification;GO:0032286//central nervous system myelin maintenance;GO:0032287//peripheral nervous system myelin maintenance;GO:0042127//regulation of cell population proliferation;GO:0042634//regulation of hair cycle;GO:0044857//plasma membrane raft organization;GO:0046513//ceramide biosynthetic process;GO:0061436//establishment of skin barrier	--
ENSG00000103091	9.321	8.798	9.413	10.135	11.487	11.104	629	619	473	472	547	464	WDR59	WD repeat domain 59 [Source:HGNC Symbol;Acc:HGNC:25706]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20409	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0061700//GATOR2 complex	GO:0005515//protein binding	GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:1904262//negative regulation of TORC1 signaling;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000103111	12.826	15.885	14.549	16.55	15.508	13.181	944	1035	757	658	826	730	MON1B	"MON1 homolog B, secretory trafficking associated [Source:HGNC Symbol;Acc:HGNC:25020]"	-	-	-	-	GO:0005737//cytoplasm;GO:0035658//Mon1-Ccz1 complex	GO:0005515//protein binding	GO:0006623//protein targeting to vacuole;GO:0016192//vesicle-mediated transport;GO:0019085//early viral transcription;GO:0019086//late viral transcription	--
ENSG00000103121	12.773	10.612	12.611	13.359	11.168	16.307	258	204.95	179	177	187	232.81	CMC2	C-X9-C motif containing 2 [Source:HGNC Symbol;Acc:HGNC:24447]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000103126	8.463	9.671	9.573	9.141	9.776	10.682	601	695	505	481	592	554	AXIN1	axin 1 [Source:HGNC Symbol;Acc:HGNC:903]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05210//Colorectal cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer	K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157;K02157	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030877//beta-catenin destruction complex;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:1990909//Wnt signalosome	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030159//signaling receptor complex adaptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0035591//signaling adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0046332//SMAD binding;GO:0060090//molecular adaptor activity;GO:0070016//armadillo repeat domain binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding	"GO:0000209//protein polyubiquitination;GO:0001701//in utero embryonic development;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006913//nucleocytoplasmic transport;GO:0006915//apoptotic process;GO:0007605//sensory perception of sound;GO:0009950//dorsal/ventral axis specification;GO:0009953//dorsal/ventral pattern formation;GO:0010629//negative regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0016055//Wnt signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030163//protein catabolic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031122//cytoplasmic microtubule organization;GO:0031398//positive regulation of protein ubiquitination;GO:0032147//activation of protein kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0034622//cellular protein-containing complex assembly;GO:0036342//post-anal tail morphogenesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043507//positive regulation of JUN kinase activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0048318//axial mesoderm development;GO:0048320//axial mesoderm formation;GO:0051248//negative regulation of protein metabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0060070//canonical Wnt signaling pathway;GO:0060322//head development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0071514//genetic imprinting;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000103145	21.455	19.303	22.253	27.444	21.169	24.297	309.84	279.25	241.61	286	262	241.29	HCFC1R1	host cell factor C1 regulator 1 [Source:HGNC Symbol;Acc:HGNC:21198]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	-	-	--
ENSG00000103148	20.134	20.163	18.938	23.462	22.018	22.227	853.86	791.63	623.86	755.83	772.67	723.01	NPRL3	"NPR3 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:14124]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20406	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:1990130//GATOR1 complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0003281//ventricular septum development;GO:0010508//positive regulation of autophagy;GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0035909//aorta morphogenesis;GO:0038202//TORC1 signaling;GO:0048738//cardiac muscle tissue development;GO:0050790//regulation of catalytic activity;GO:0060021//roof of mouth development;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000103150	1.991	1.867	2.09	2.169	2.068	1.792	539	508	418	435	438	353	MLYCD	malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150]	Metabolism;Human Diseases;Environmental Information Processing;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Signal transduction;Transport and catabolism;Carbohydrate metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04146//Peroxisome;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism	K01578;K01578;K01578;K01578;K01578;K01578	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0042802//identical protein binding;GO:0050080//malonyl-CoA decarboxylase activity	GO:0002931//response to ischemia;GO:0006085//acetyl-CoA biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0010906//regulation of glucose metabolic process;GO:0019395//fatty acid oxidation;GO:0031998//regulation of fatty acid beta-oxidation;GO:0046320//regulation of fatty acid oxidation;GO:0046321//positive regulation of fatty acid oxidation;GO:2001294//malonyl-CoA catabolic process	--
ENSG00000103152	17.892	21.139	21.159	25.041	25.376	19.698	385.14	457.37	336.14	399.17	463.33	307.99	MPG	N-methylpurine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7211]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K03652	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042645//mitochondrial nucleoid	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003824//catalytic activity;GO:0003905//alkylbase DNA N-glycosylase activity;GO:0005515//protein binding;GO:0008725//DNA-3-methyladenine glycosylase activity;GO:0016787//hydrolase activity;GO:0019104//DNA N-glycosylase activity;GO:0043916//DNA-7-methylguanine glycosylase activity;GO:0052821//DNA-7-methyladenine glycosylase activity;GO:0052822//DNA-3-methylguanine glycosylase activity	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0045007//depurination	--
ENSG00000103154	2.749	2.215	1.987	4.082	4.1	2.773	88	80	61	126	107	80	NECAB2	N-terminal EF-hand calcium binding protein 2 [Source:HGNC Symbol;Acc:HGNC:23746]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031687//A2A adenosine receptor binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0042984//regulation of amyloid precursor protein biosynthetic process;GO:0060168//positive regulation of adenosine receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900451//positive regulation of glutamate receptor signaling pathway;GO:1904021//negative regulation of G protein-coupled receptor internalization;GO:1905477//positive regulation of protein localization to membrane	--
ENSG00000103160	13.797	12.096	14.083	13.501	10.774	11.952	1044	920	787	748	676	658	HSDL1	hydroxysteroid dehydrogenase like 1 [Source:HGNC Symbol;Acc:HGNC:16475]	-	-	-	-	GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding;GO:0016491//oxidoreductase activity	-	--
ENSG00000103168	3.951	4.462	5.712	4.134	4.782	4.388	279	287	241	208	270	222	TAF1C	"TATA-box binding protein associated factor, RNA polymerase I subunit C [Source:HGNC Symbol;Acc:HGNC:11534]"	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0001181//RNA polymerase I general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006360//transcription by RNA polymerase I;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II	--
ENSG00000103174	4.042	4.16	4.428	3.503	4.285	3.584	159	177	126	119	163	114	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [Source:HGNC Symbol;Acc:HGNC:17378]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K01125	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0003944//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006622//protein targeting to lysosome;GO:0007040//lysosome organization;GO:0033299//secretion of lysosomal enzymes	--
ENSG00000103175	0.261	0.479	0.099	0.251	0.397	0.1	7	13	2	5	9	2	WFDC1	WAP four-disulfide core domain 1 [Source:HGNC Symbol;Acc:HGNC:15466]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0001558//regulation of cell growth;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030308//negative regulation of cell growth;GO:0050728//negative regulation of inflammatory response;GO:0061045//negative regulation of wound healing	--
ENSG00000103184	0.045	0.022	0.02	0.141	0.053	0.103	6	3	2	14	6	10	SEC14L5	SEC14 like lipid binding 5 [Source:HGNC Symbol;Acc:HGNC:29032]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000103187	159.418	164.587	147.917	129.336	122.137	108.919	6049	6299	4153	3645	3898	3002	COTL1	coactosin like F-actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18304]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0051015//actin filament binding	GO:0008150//biological_process;GO:0030833//regulation of actin filament polymerization;GO:0050832//defense response to fungus	--
ENSG00000103194	25.293	25.583	25.693	24.117	25.248	25.249	1736	1749	1273	1195	1418	1244	USP10	ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0045111//intermediate filament cytoskeleton	GO:0002039//p53 binding;GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0044325//transmembrane transporter binding	"GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0006974//cellular response to DNA damage stimulus;GO:0010506//regulation of autophagy;GO:0016579//protein deubiquitination;GO:0019985//translesion synthesis;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071347//cellular response to interleukin-1"	--
ENSG00000103196	1.809	2.418	1.097	0.653	1.43	0.804	172	231	77	46	111	49	CRISPLD2	cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030133//transport vesicle;GO:0031012//extracellular matrix;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding	GO:0030198//extracellular matrix organization;GO:0030324//lung development;GO:0060325//face morphogenesis	--
ENSG00000103197	24.292	24.507	24.142	29.903	28.675	23.958	2483	2615	1989	1929.83	2521.06	1872	TSC2	TSC complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:12363]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: viral;Signal transduction;Infectious disease: viral;Environmental adaptation;Infectious disease: viral;Signal transduction;Signal transduction;Cell growth and death;Transport and catabolism;Endocrine system;Endocrine system;Signal transduction;Cancer: overview;Aging;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko05231//Choline metabolism in cancer;ko04211//Longevity regulating pathway;ko04115//p53 signaling pathway	K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207;K07207	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0033596//TSC1-TSC2 complex;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity;GO:0051879//Hsp90 protein binding	GO:0001843//neural tube closure;GO:0006469//negative regulation of protein kinase activity;GO:0006606//protein import into nucleus;GO:0006897//endocytosis;GO:0007507//heart development;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016192//vesicle-mediated transport;GO:0016239//positive regulation of macroautophagy;GO:0030100//regulation of endocytosis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032007//negative regulation of TOR signaling;GO:0043276//anoikis;GO:0043491//protein kinase B signaling;GO:0043547//positive regulation of GTPase activity;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051726//regulation of cell cycle;GO:0051898//negative regulation of protein kinase B signaling;GO:1901525//negative regulation of mitophagy	--
ENSG00000103199	2.223	3.614	3.223	3.564	4.006	3.76	157.55	207.58	139.55	159	215	156	ZNF500	zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000103202	81.207	81.972	82.352	80.257	75.81	81.316	1700.02	1727	1275	1249	1339.02	1236	NME4	NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1901612//cardiolipin binding	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006869//lipid transport;GO:0009116//nucleoside metabolic process;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000103222	30.051	31.162	32.015	31.996	34.201	34.79	4044	4216	3182	3189	3887	3403	ABCC1	ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Membrane transport;Drug resistance: antineoplastic;Digestive system	ko05206//MicroRNAs in cancer;ko04071//Sphingolipid signaling pathway;ko02010//ABC transporters;ko01523//Antifolate resistance;ko04977//Vitamin digestion and absorption	K05665;K05665;K05665;K05665;K05665	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015420//ABC-type vitamin B12 transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0016787//hydrolase activity;GO:0022857//transmembrane transporter activity;GO:0034040//ATPase-coupled lipid transmembrane transporter activity;GO:0034634//glutathione transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006691//leukotriene metabolic process;GO:0006869//lipid transport;GO:0009235//cobalamin metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0015698//inorganic anion transport;GO:0015889//cobalamin transport;GO:0034599//cellular response to oxidative stress;GO:0034775//glutathione transmembrane transport;GO:0042167//heme catabolic process;GO:0042908//xenobiotic transport;GO:0045332//phospholipid translocation;GO:0050729//positive regulation of inflammatory response;GO:0055085//transmembrane transport;GO:0060326//cell chemotaxis;GO:0070633//transepithelial transport;GO:0071716//leukotriene transport;GO:0099039//sphingolipid translocation;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1904646//cellular response to amyloid-beta;GO:1905039//carboxylic acid transmembrane transport;GO:1990962//xenobiotic transport across blood-brain barrier	--
ENSG00000103226	26.383	27.48	25.534	32.065	29.212	26.343	2177.52	2283.56	1569.94	1742.05	2052.63	1591.05	NOMO3	NODAL modulator 3 [Source:HGNC Symbol;Acc:HGNC:25242]	-	-	-	-	GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043022//ribosome binding	GO:1900108//negative regulation of nodal signaling pathway	--
ENSG00000103227	16.413	15.086	16.894	22.135	19.571	18.705	773	723	596	781	802	677	LMF1	lipase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:14154]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006641//triglyceride metabolic process;GO:0051604//protein maturation	--
ENSG00000103241	0	0	0.074	0	0	0.019	0	0	4	0	0	1	FOXF1	forkhead box F1 [Source:HGNC Symbol;Acc:HGNC:3809]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001763//morphogenesis of a branching structure;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003197//endocardial cushion development;GO:0003214//cardiac left ventricle morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007494//midgut development;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0009887//animal organ morphogenesis;GO:0010811//positive regulation of cell-substrate adhesion;GO:0014822//detection of wounding;GO:0030198//extracellular matrix organization;GO:0030323//respiratory tube development;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0031016//pancreas development;GO:0043305//negative regulation of mast cell degranulation;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048371//lateral mesodermal cell differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0048565//digestive tract development;GO:0048566//embryonic digestive tract development;GO:0048613//embryonic ectodermal digestive tract morphogenesis;GO:0048617//embryonic foregut morphogenesis;GO:0050728//negative regulation of inflammatory response;GO:0051145//smooth muscle cell differentiation;GO:0060425//lung morphogenesis;GO:0060426//lung vasculature development;GO:0060438//trachea development;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060461//right lung morphogenesis;GO:0060463//lung lobe morphogenesis;GO:0060841//venous blood vessel development;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0071345//cellular response to cytokine stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0072189//ureter development;GO:0090131//mesenchyme migration;GO:0097070//ductus arteriosus closure;GO:0098609//cell-cell adhesion"	Fork_head
ENSG00000103245	10.254	9.269	13.425	12.162	12.662	13.166	447	406	422	392	450	417	CIAO3	cytosolic iron-sulfur assembly component 3 [Source:HGNC Symbol;Acc:HGNC:14179]	-	-	-	-	GO:0097361//CIA complex	"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0001666//response to hypoxia;GO:0002244//hematopoietic progenitor cell differentiation;GO:0010468//regulation of gene expression;GO:0016226//iron-sulfur cluster assembly;GO:0032364//oxygen homeostasis	--
ENSG00000103248	6.726	7.307	7.274	6.256	8.328	6.577	274	280	231	191	264	197	MTHFSD	methenyltetrahydrofolate synthetase domain containing [Source:HGNC Symbol;Acc:HGNC:25778]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000103249	41.367	44.949	42.824	48.904	49.896	48.724	3557	3877	2726	3106	3617	3054	CLCN7	chloride voltage-gated channel 7 [Source:HGNC Symbol;Acc:HGNC:2025]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0034707//chloride channel complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015108//chloride transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0009268//response to pH;GO:0030321//transepithelial chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000103253	4.627	3.798	5.39	5.626	5.814	5.901	140	98	115	117	106	129	HAGHL	hydroxyacylglutathione hydrolase like [Source:HGNC Symbol;Acc:HGNC:14177]	-	-	-	-	-	GO:0004416//hydroxyacylglutathione hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0019243//methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	--
ENSG00000103254	8.256	6.227	7.836	8.924	8.388	7.331	133	112	102	119	129	92	ANTKMT	adenine nucleotide translocase lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:14152]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	"GO:0018022//peptidyl-lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation;GO:1905273//positive regulation of proton-transporting ATP synthase activity, rotational mechanism;GO:1905706//regulation of mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000103257	260.141	279.783	262.073	343.324	339.115	322.564	24485	26373	18235	23819	26968	21977	SLC7A5	solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063]	Environmental Information Processing;Human Diseases	Signal transduction;Cancer: overview	ko04150//mTOR signaling pathway;ko05230//Central carbon metabolism in cancer	K13780;K13780	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0098591//external side of apical plasma membrane;GO:1990184//amino acid transport complex	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0015196//L-tryptophan transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042605//peptide antigen binding	GO:0002720//positive regulation of cytokine production involved in immune response;GO:0006865//amino acid transport;GO:0010629//negative regulation of gene expression;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015823//phenylalanine transport;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0032753//positive regulation of interleukin-4 production;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport;GO:0089718//amino acid import across plasma membrane;GO:0098713//leucine import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903801//L-leucine import across plasma membrane;GO:1904556//L-tryptophan transmembrane transport	--
ENSG00000103260	44.847	47.024	52.863	79.481	62.301	59.746	1211	1243	908	1407	1440	1108	METRN	"meteorin, glial cell differentiation regulator [Source:HGNC Symbol;Acc:HGNC:14151]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010001//glial cell differentiation;GO:0030154//cell differentiation;GO:0050772//positive regulation of axonogenesis	--
ENSG00000103264	10.083	11.087	10.377	13.554	11.906	15.586	819.76	856	667.23	672	755.72	670	FBXO31	F-box protein 31 [Source:HGNC Symbol;Acc:HGNC:16510]	-	-	-	-	GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019005//SCF ubiquitin ligase complex;GO:0043025//neuronal cell body	GO:0005515//protein binding;GO:0030332//cyclin binding	GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0050775//positive regulation of dendrite morphogenesis;GO:2001224//positive regulation of neuron migration	--
ENSG00000103266	44.644	46.389	51.695	57.62	51.095	50.116	1222.97	1291.76	1060.43	1178.31	1190.12	1007.35	STUB1	STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K09561;K09561	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0030018//Z disc;GO:0031371//ubiquitin conjugating enzyme complex;GO:0042405//nuclear inclusion body;GO:0101031//chaperone complex	GO:0001664//G protein-coupled receptor binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0030544//Hsp70 protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0030911//TPR domain binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0042803//protein homodimerization activity;GO:0046332//SMAD binding;GO:0048156//tau protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding;GO:0051879//Hsp90 protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002931//response to ischemia;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031398//positive regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0031943//regulation of glucocorticoid metabolic process;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034605//cellular response to heat;GO:0038128//ERBB2 signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045862//positive regulation of proteolysis;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0051604//protein maturation;GO:0051865//protein autoubiquitination;GO:0061684//chaperone-mediated autophagy;GO:0070534//protein K63-linked ubiquitination;GO:0071218//cellular response to misfolded protein;GO:0071456//cellular response to hypoxia;GO:0090035//positive regulation of chaperone-mediated protein complex assembly	--
ENSG00000103269	0.628	0.974	1.054	0.848	1.455	1.182	19	30	24	19	38	26	RHBDL1	rhomboid like 1 [Source:HGNC Symbol;Acc:HGNC:10007]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007165//signal transduction	--
ENSG00000103274	18.398	17.908	19.477	14.99	19.583	19.22	424.92	449.94	350.82	272.81	386	343.96	NUBP1	nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8041]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0001558//regulation of cell growth;GO:0006879//cellular iron ion homeostasis;GO:0010826//negative regulation of centrosome duplication;GO:0016226//iron-sulfur cluster assembly;GO:0030030//cell projection organization;GO:0051642//centrosome localization;GO:0072697//protein localization to cell cortex	--
ENSG00000103275	21.918	26.722	24.708	23.075	26.077	25.349	987	1196	770	748	937	778	UBE2I	ubiquitin conjugating enzyme E2 I [Source:HGNC Symbol;Acc:HGNC:12485]	Environmental Information Processing;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Signal transduction;Cancer: overview;Folding, sorting and degradation;Translation"	ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04120//Ubiquitin mediated proteolysis;ko03013//Nucleocytoplasmic transport	K10577;K10577;K10577;K10577	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016605//PML body;GO:0106068//SUMO ligase complex;GO:1990234//transferase complex;GO:1990356//sumoylated E2 ligase complex	GO:0000166//nucleotide binding;GO:0001221//transcription coregulator binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008134//transcription factor binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019789//SUMO transferase activity;GO:0019899//enzyme binding;GO:0043398//HLH domain binding;GO:0044388//small protein activating enzyme binding;GO:0061656//SUMO conjugating enzyme activity;GO:0071535//RING-like zinc finger domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007084//mitotic nuclear membrane reassembly;GO:0016925//protein sumoylation;GO:0032446//protein modification by small protein conjugation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051168//nuclear export;GO:0051301//cell division;GO:1903755//positive regulation of SUMO transferase activity"	--
ENSG00000103310	0	0	0	0	0	0	0	0	0	0	0	0	ZP2	zona pellucida glycoprotein 2 [Source:HGNC Symbol;Acc:HGNC:13188]	-	-	-	-	GO:0005576//extracellular region;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035805//egg coat;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0032190//acrosin binding;GO:0035804//structural constituent of egg coat;GO:0042802//identical protein binding	GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0060468//prevention of polyspermy	--
ENSG00000103313	0	0.016	0.063	0	0	0	0	1	1	0	0	0	MEFV	"MEFV innate immuity regulator, pyrin [Source:HGNC Symbol;Acc:HGNC:6998]"	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway	K12803;K12803	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0061702//inflammasome complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032651//regulation of interleukin-1 beta production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032695//negative regulation of interleukin-12 production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0034341//response to interferon-gamma;GO:0045087//innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0070269//pyroptosis;GO:0071641//negative regulation of macrophage inflammatory protein 1 alpha production;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1904270//pyroptosome complex assembly;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000103316	0.28	0.587	0.325	2.016	1.376	2.251	8	9	5	40	30	39	CRYM	crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042562//hormone binding;GO:0042803//protein homodimerization activity;GO:0047127//thiomorpholine-carboxylate dehydrogenase activity;GO:0050661//NADP binding;GO:0070324//thyroid hormone binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006554//lysine catabolic process;GO:0007605//sensory perception of sound;GO:0042403//thyroid hormone metabolic process;GO:0070327//thyroid hormone transport	--
ENSG00000103319	6.728	7.7	7.567	6.619	6.819	6.624	1000	1142	820	719	861	689	EEF2K	eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615]	Organismal Systems;Environmental Information Processing	Endocrine system;Signal transduction	ko04921//Oxytocin signaling pathway;ko04152//AMPK signaling pathway	K08292;K08292	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0043197//dendritic spine	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004686//elongation factor-2 kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008135//translation factor activity, RNA binding;GO:0016301//kinase activity;GO:0016740//transferase activity"	GO:0002931//response to ischemia;GO:0006414//translational elongation;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0031952//regulation of protein autophosphorylation;GO:0032869//cellular response to insulin stimulus;GO:0043066//negative regulation of apoptotic process;GO:0045807//positive regulation of endocytosis;GO:0046777//protein autophosphorylation;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071277//cellular response to calcium ion;GO:0071320//cellular response to cAMP;GO:0071454//cellular response to anoxia;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus;GO:1990637//response to prolactin	--
ENSG00000103326	4.47	4.852	6.011	6.448	5.518	6.525	358	353	318	331	327	319	CAPN15	calpain 15 [Source:HGNC Symbol;Acc:HGNC:11182]	-	-	-	-	GO:0005737//cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	Others
ENSG00000103335	21.987	27.41	26.469	30.045	30.492	31.535	3606	3664	2940	3359	3996	3521	PIEZO1	piezo type mechanosensitive ion channel component 1 [Source:HGNC Symbol;Acc:HGNC:28993]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031258//lamellipodium membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042995//cell projection	GO:0005261//cation channel activity;GO:0005515//protein binding;GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0010831//positive regulation of myotube differentiation;GO:0033625//positive regulation of integrin activation;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050982//detection of mechanical stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0098655//cation transmembrane transport	--
ENSG00000103342	36.771	30.462	34.06	26.242	30.611	31.482	2374	2029	1565	1286	1595	1459	GSPT1	G1 to S phase transition 1 [Source:HGNC Symbol;Acc:HGNC:4621]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K03267	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0018444//translation release factor complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003747//translation release factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002184//cytoplasmic translational termination;GO:0006412//translation;GO:0006415//translational termination;GO:0006449//regulation of translational termination;GO:0006479//protein methylation"	--
ENSG00000103343	6.112	6.107	8.221	6.966	7.784	7.176	298	272	241	222	276	225	ZNF174	zinc finger protein 174 [Source:HGNC Symbol;Acc:HGNC:12963]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000103351	11.629	10.667	12.305	7.715	8.244	9.555	421	379	319	219	312	261	CLUAP1	clusterin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:19009]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097542//ciliary tip	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0035720//intraciliary anterograde transport;GO:0060271//cilium assembly	--
ENSG00000103353	42.726	42.778	41.301	36.879	51.461	47.134	2932	2959	2368	2136	2647	2309	UBFD1	ubiquitin family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30565]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	-	--
ENSG00000103355	198.429	227.937	199.123	157.968	166.796	145.892	6697	7750	4971	3995	4793	3618	PRSS33	serine protease 33 [Source:HGNC Symbol;Acc:HGNC:30405]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0070528//protein kinase C signaling	--
ENSG00000103356	6.799	8.081	8.812	8.014	8.338	6.965	584	685	507	511	569	373	EARS2	"glutamyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29419]"	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00860//Porphyrin metabolism	K01885;K01885;K01885	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0110165//cellular anatomical entity	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004818//glutamate-tRNA ligase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0050561//glutamate-tRNA(Gln) ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006424//glutamyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0070127//tRNA aminoacylation for mitochondrial protein translation	--
ENSG00000103363	63.877	67.723	71.436	68.277	61.714	65.164	1133	1173	929	885	820	873	ELOB	elongin B [Source:HGNC Symbol;Acc:HGNC:11619]	Human Diseases;Human Diseases;Genetic Information Processing;Environmental Information Processing;Human Diseases	"Cancer: overview;Infectious disease: viral;Folding, sorting and degradation;Signal transduction;Cancer: specific types"	ko05200//Pathways in cancer;ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K03873;K03873;K03873;K03873;K03873	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030891//VCB complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0070449//elongin complex	GO:0001222//transcription corepressor binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006414//translational elongation;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0065003//protein-containing complex assembly	--
ENSG00000103365	49.632	50.349	52.479	55.688	56.353	54.208	6149	6207	4541	4938	5640	4667	GGA2	"golgi associated, gamma adaptin ear containing, ARF binding protein 2 [Source:HGNC Symbol;Acc:HGNC:16064]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12404	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0034394//protein localization to cell surface;GO:0043001//Golgi to plasma membrane protein transport	--
ENSG00000103375	0	0	0	0	0.045	0	0	0	0	0	1	0	AQP8	aquaporin 8 [Source:HGNC Symbol;Acc:HGNC:642]	Organismal Systems	Digestive system	ko04976//Bile secretion	K09869	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045177//apical part of cell	GO:0005515//protein binding;GO:0015250//water channel activity;GO:0015267//channel activity	GO:0006833//water transport;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP	--
ENSG00000103381	5.598	5.511	4.638	4.197	5.72	4.983	366	359	246	223	288	238	CPPED1	calcineurin like phosphoesterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25632]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0035578//azurophil granule lumen	GO:0004722//protein serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000103404	1.355	0.991	1.207	1.03	0.957	1.537	247	209	175	148	158	196	USP31	ubiquitin specific peptidase 31 [Source:HGNC Symbol;Acc:HGNC:20060]	-	-	-	-	GO:0005634//nucleus	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000103415	26.067	27.842	25.937	33.132	28.18	31.169	718	750	531	630	646	594	HMOX2	heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04978//Mineral absorption;ko00860//Porphyrin metabolism	K21418;K21418;K21418	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004392//heme oxygenase (decyclizing) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0006788//heme oxidation;GO:0006979//response to oxidative stress;GO:0042167//heme catabolic process;GO:0055072//iron ion homeostasis	--
ENSG00000103423	18.415	16.843	20.064	19.145	18.061	22.478	993	907	803	762	795	859	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3 [Source:HGNC Symbol;Acc:HGNC:11808]	Human Diseases	Cancer: overview	ko05203//Viral carcinogenesis	K09504	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0042645//mitochondrial nucleoid;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005133//interferon-gamma receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding;GO:0030695//GTPase regulator activity;GO:0031072//heat shock protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0051082//unfolded protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106137//IkappaB kinase complex binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006264//mitochondrial DNA replication;GO:0006457//protein folding;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0007005//mitochondrion organization;GO:0007264//small GTPase mediated signal transduction;GO:0007528//neuromuscular junction development;GO:0007569//cell aging;GO:0008285//negative regulation of cell population proliferation;GO:0009408//response to heat;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033077//T cell differentiation in thymus;GO:0034341//response to interferon-gamma;GO:0042102//positive regulation of T cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0071340//skeletal muscle acetylcholine-gated channel clustering	--
ENSG00000103426	0.153	0.131	0	0	0.203	0.082	10.39	10.39	0	0	11.7	4.71	CORO7-PAM16	CORO7-PAM16 readthrough [Source:HGNC Symbol;Acc:HGNC:44424]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000103429	31.828	29.521	36.966	35.584	37.572	34.624	1567	1504	1227	1292	1455	1265	BFAR	bifunctional apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:17613]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0089720//caspase binding	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:1903895//negative regulation of IRE1-mediated unfolded protein response	--
ENSG00000103449	0.462	0.387	0.439	1.231	1.37	1.113	46	40	34	89	109	86	SALL1	spalt like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10524]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010369//chromocenter	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0003281//ventricular septum development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008406//gonad development;GO:0021553//olfactory nerve development;GO:0021889//olfactory bulb interneuron differentiation;GO:0021983//pituitary gland development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030325//adrenal gland development;GO:0031129//inductive cell-cell signaling;GO:0042733//embryonic digit morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048566//embryonic digestive tract development;GO:0060173//limb development;GO:0061034//olfactory bulb mitral cell layer development;GO:0072073//kidney epithelium development;GO:0072092//ureteric bud invasion"	zf-C2H2
ENSG00000103460	0.952	1.869	1.357	0.364	0.355	0.691	68	73	50	23	24	24	TOX3	TOX high mobility group box family member 3 [Source:HGNC Symbol;Acc:HGNC:11972]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II	HMG
ENSG00000103479	15.826	15.312	15.638	12.39	15.512	16.763	1593.38	1549.6	1162.82	924.05	1319.45	1227.97	RBL2	RB transcriptional corepressor like 2 [Source:HGNC Symbol;Acc:HGNC:9894]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes	Signal transduction;Infectious disease: viral;Cancer: overview;Cell growth and death;Signal transduction;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis;ko04218//Cellular senescence;ko04068//FoxO signaling pathway;ko04110//Cell cycle	K16332;K16332;K16332;K16332;K16332;K16332	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990841//promoter-specific chromatin binding	GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0043550//regulation of lipid kinase activity;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000103485	138.537	139.924	153.849	164.277	143.479	177.333	5298	5407	4357	4624	4659	4970	QPRT	quinolinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:9755]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00767;K00767	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1902494//catalytic complex	GO:0003824//catalytic activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042802//identical protein binding	GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019674//NAD metabolic process;GO:0034213//quinolinate catabolic process	--
ENSG00000103489	3.869	4.032	4.544	2.761	3.297	4.406	800	838	694	423	576	663	XYLT1	xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15516]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00771;K00771;K00771	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030158//protein xylosyltransferase activity;GO:0046872//metal ion binding	GO:0006024//glycosaminoglycan biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0043931//ossification involved in bone maturation;GO:0048706//embryonic skeletal system development;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process	--
ENSG00000103490	0.999	1.133	0.604	1.065	1.185	1.568	16	18	7	13	16	18	PYCARD	PYD and CARD domain containing [Source:HGNC Symbol;Acc:HGNC:16608]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: bacterial;Immune system;Infectious disease: viral;Cell growth and death;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko04625//C-type lectin receptor signaling pathway;ko05133//Pertussis;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis	K12799;K12799;K12799;K12799;K12799;K12799;K12799;K12799;K12799;K12799;K12799;K12799	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0008385//IkappaB kinase complex;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0043025//neuronal cell body;GO:0061702//inflammasome complex;GO:0072558//NLRP1 inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097169//AIM2 inflammasome complex	GO:0002020//protease binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0017024//myosin I binding;GO:0019899//enzyme binding;GO:0032090//Pyrin domain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0046983//protein dimerization activity;GO:0070700//BMP receptor binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process	GO:0001773//myeloid dendritic cell activation;GO:0002218//activation of innate immune response;GO:0002221//pattern recognition receptor signaling pathway;GO:0002230//positive regulation of defense response to virus by host;GO:0002277//myeloid dendritic cell activation involved in immune response;GO:0002376//immune system process;GO:0002588//positive regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0002821//positive regulation of adaptive immune response;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007231//osmosensory signaling pathway;GO:0009617//response to bacterium;GO:0010506//regulation of autophagy;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0030838//positive regulation of actin filament polymerization;GO:0031647//regulation of protein stability;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032688//negative regulation of interferon-beta production;GO:0032722//positive regulation of chemokine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044351//macropinocytosis;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0046456//icosanoid biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050870//positive regulation of T cell activation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization;GO:0051607//defense response to virus;GO:0051707//response to other organism;GO:0070269//pyroptosis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:2000406//positive regulation of T cell migration;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001242//regulation of intrinsic apoptotic signaling pathway	--
ENSG00000103494	5.402	3.588	4.177	2.536	2.493	4.348	432	343	208	139	178	211	RPGRIP1L	RPGRIP1 like [Source:HGNC Symbol;Acc:HGNC:29168]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005879//axonemal microtubule;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0005929//cilium;GO:0005930//axoneme;GO:0030054//cell junction;GO:0032391//photoreceptor connecting cilium;GO:0035253//ciliary rootlet;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0031870//thromboxane A2 receptor binding	GO:0001701//in utero embryonic development;GO:0001736//establishment of planar polarity;GO:0001822//kidney development;GO:0001889//liver development;GO:0007163//establishment or maintenance of cell polarity;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0008589//regulation of smoothened signaling pathway;GO:0021532//neural tube patterning;GO:0021537//telencephalon development;GO:0021549//cerebellum development;GO:0021670//lateral ventricle development;GO:0021772//olfactory bulb development;GO:0022038//corpus callosum development;GO:0032502//developmental process;GO:0035108//limb morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0043010//camera-type eye development;GO:0043584//nose development;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0046548//retinal rod cell development;GO:0060039//pericardium development;GO:0060271//cilium assembly;GO:0060322//head development;GO:0090102//cochlea development;GO:1905515//non-motile cilium assembly	--
ENSG00000103495	111.684	111.777	120.264	134.827	121.293	126.026	4758	4963	3977	4520	4691	4182	MAZ	MYC associated zinc finger protein [Source:HGNC Symbol;Acc:HGNC:6914]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006369//termination of RNA polymerase II transcription;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030335//positive regulation of cell migration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051897//positive regulation of protein kinase B signaling;GO:2001234//negative regulation of apoptotic signaling pathway"	zf-C2H2
ENSG00000103496	16.056	14.732	16.007	22.635	17.563	19.998	425	391	311	436	374	370	STX4	syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439]	Organismal Systems;Genetic Information Processing	"Excretory system;Folding, sorting and degradation"	ko04962//Vasopressin-regulated water reabsorption;ko04130//SNARE interactions in vesicular transport	K13502;K13502	GO:0000322//storage vacuole;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005773//vacuole;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0030670//phagocytic vesicle membrane;GO:0031201//SNARE complex;GO:0032589//neuron projection membrane;GO:0035749//myelin sheath adaxonal region;GO:0036477//somatodendritic compartment;GO:0042581//specific granule;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043219//lateral loop;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0048787//presynaptic active zone membrane;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0016230//sphingomyelin phosphodiesterase activator activity	GO:0002639//positive regulation of immunoglobulin production;GO:0006836//neurotransmitter transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0008284//positive regulation of cell population proliferation;GO:0016192//vesicle-mediated transport;GO:0017157//regulation of exocytosis;GO:0030335//positive regulation of cell migration;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0034394//protein localization to cell surface;GO:0034599//cellular response to oxidative stress;GO:0035493//SNARE complex assembly;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0043085//positive regulation of catalytic activity;GO:0043311//positive regulation of eosinophil degranulation;GO:0045785//positive regulation of cell adhesion;GO:0048278//vesicle docking;GO:0048284//organelle fusion;GO:0050921//positive regulation of chemotaxis;GO:0060291//long-term synaptic potentiation;GO:0071346//cellular response to interferon-gamma;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903575//cornified envelope assembly;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000103502	51.945	54.516	62.213	61.293	59.668	56.251	1843	1943	1615	1600	1783	1481	CDIPT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769]	Metabolism;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Lipid metabolism;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00999;K00999;K00999;K00999	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003881//CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0019992//diacylglycerol binding;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0043178//alcohol binding"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0046341//CDP-diacylglycerol metabolic process	--
ENSG00000103507	20.941	24.912	23.568	23.849	22.596	23.004	868	1050	723	742	799	683	BCKDK	branched chain keto acid dehydrogenase kinase [Source:HGNC Symbol;Acc:HGNC:16902]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0047323//[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity"	GO:0006468//protein phosphorylation;GO:0009063//cellular amino acid catabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0010906//regulation of glucose metabolic process;GO:0016310//phosphorylation;GO:0045763//negative regulation of cellular amino acid metabolic process	--
ENSG00000103510	12.061	13.051	14.456	14.408	15.541	13.263	380	416	337	346	414	305	KAT8	lysine acetyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:17933]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016363//nuclear matrix;GO:0044545//NSL complex;GO:0071339//MLL1 complex;GO:0072487//MSL complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0010484//H3 histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019899//enzyme binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0046872//metal ion binding;GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0010506//regulation of autophagy;GO:0016573//histone acetylation;GO:0030099//myeloid cell differentiation;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000103512	59.847	62.332	59.849	60.978	64.739	57.666	5352.67	5603.61	3953.46	3980.96	4874.03	3752.67	NOMO1	NODAL modulator 1 [Source:HGNC Symbol;Acc:HGNC:30060]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043022//ribosome binding	GO:0008150//biological_process	--
ENSG00000103522	0.133	0.081	0.044	0.088	0.06	0	10	5	2	4	5	0	IL21R	interleukin 21 receptor [Source:HGNC Symbol;Acc:HGNC:6006]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Signal transduction;Immune system;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease	K05075;K05075;K05075;K05075	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001532//interleukin-21 receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0005515//protein binding	GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0030101//natural killer cell activation;GO:0038114//interleukin-21-mediated signaling pathway	--
ENSG00000103528	23.601	21.974	23.154	20.713	22.423	26.75	1148	1088	853	772	900	969	SYT17	synaptotagmin 17 [Source:HGNC Symbol;Acc:HGNC:24119]	-	-	-	-	GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070382//exocytic vesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding	GO:0006887//exocytosis;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0030154//cell differentiation;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000103534	2.935	2.204	3.109	2.556	2.733	3.558	200	206	155	166	197	208	TMC5	transmembrane channel like 5 [Source:HGNC Symbol;Acc:HGNC:22999]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport	--
ENSG00000103540	2.54	1.941	1.756	2.558	1.395	1.328	289	218	125	115	137	111	CCP110	centriolar coiled-coil protein 110 [Source:HGNC Symbol;Acc:HGNC:24342]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0032991//protein-containing complex;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007099//centriole replication;GO:0030030//cell projection organization;GO:0032053//ciliary basal body organization;GO:0032465//regulation of cytokinesis;GO:0045724//positive regulation of cilium assembly;GO:0051298//centrosome duplication;GO:1902018//negative regulation of cilium assembly;GO:1903723//negative regulation of centriole elongation	--
ENSG00000103544	21.145	23.012	21.753	26.378	25.823	23.354	1574	1700	1199	1432	1604	1209	VPS35L	VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding	GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0032456//endocytic recycling	--
ENSG00000103546	0	0.015	0.029	0	0	0.021	0	1	1	0	0	1	SLC6A2	solute carrier family 6 member 2 [Source:HGNC Symbol;Acc:HGNC:11048]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K05035	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0098793//presynapse	GO:0003779//actin binding;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005328//neurotransmitter:sodium symporter activity;GO:0005330//dopamine:sodium symporter activity;GO:0005334//norepinephrine:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0015293//symporter activity;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding	GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0009410//response to xenobiotic stimulus;GO:0015844//monoamine transport;GO:0015874//norepinephrine transport;GO:0035725//sodium ion transmembrane transport;GO:0048265//response to pain;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051620//norepinephrine uptake;GO:0055085//transmembrane transport;GO:0070050//neuron cellular homeostasis;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0098810//neurotransmitter reuptake	--
ENSG00000103549	43.048	44.456	43.823	49.99	49.762	38.32	3262	3323.17	2480	2803	3098	2300	RNF40	ring finger protein 40 [Source:HGNC Symbol;Acc:HGNC:16867]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0032991//protein-containing complex;GO:0033503//HULC complex;GO:0043005//neuron projection;GO:0043679//axon terminus	GO:0003730//mRNA 3'-UTR binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0017075//syntaxin-1 binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010390//histone monoubiquitination;GO:0016567//protein ubiquitination;GO:0031401//positive regulation of protein modification process;GO:0033523//histone H2B ubiquitination;GO:0043434//response to peptide hormone;GO:0071894//histone H2B conserved C-terminal lysine ubiquitination;GO:1900364//negative regulation of mRNA polyadenylation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902916//positive regulation of protein polyubiquitination;GO:2001168//positive regulation of histone H2B ubiquitination	--
ENSG00000103550	6.095	7.012	10.711	7.176	8.248	6.323	410	446.19	337	329	334	284	KNOP1	lysine rich nucleolar protein 1 [Source:HGNC Symbol;Acc:HGNC:34404]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000103569	0	0	0	0	0.04	0.024	0	0	0	0	2	1	AQP9	aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643]	Organismal Systems;Organismal Systems	Immune system;Digestive system	ko04613//Neutrophil extracellular trap formation;ko04976//Bile secretion	K09877;K09877	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005350//pyrimidine nucleobase transmembrane transporter activity;GO:0005515//protein binding;GO:0015166//polyol transmembrane transporter activity;GO:0015204//urea transmembrane transporter activity;GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015265//urea channel activity;GO:0015267//channel activity	GO:0006833//water transport;GO:0006863//purine nucleobase transport;GO:0015722//canalicular bile acid transport;GO:0015791//polyol transport;GO:0015793//glycerol transport;GO:0015837//amine transport;GO:0015855//pyrimidine nucleobase transport;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071918//urea transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:1904823//purine nucleobase transmembrane transport	--
ENSG00000103591	23.62	23.482	24.712	25.704	24.079	23.869	1063	1040	781	765	809	743	AAGAB	alpha and gamma adaptin binding protein [Source:HGNC Symbol;Acc:HGNC:25662]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0005515//protein binding	GO:0015031//protein transport	--
ENSG00000103599	0.512	1.121	0.576	0.585	0.568	0.373	19	22	15	21	17	17	IQCH	IQ motif containing H [Source:HGNC Symbol;Acc:HGNC:25721]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000103642	6.026	3.786	3.914	5.853	7.215	7.76	193	173	104	171	158	165	LACTB	lactamase beta [Source:HGNC Symbol;Acc:HGNC:16468]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0019216//regulation of lipid metabolic process	--
ENSG00000103647	19.563	19.211	21.017	20.202	20.802	21.064	1399	1397	1116	1080	1268	1080	CORO2B	coronin 2B [Source:HGNC Symbol;Acc:HGNC:2256]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017166//vinculin binding;GO:0051015//actin filament binding;GO:1990147//talin binding	GO:0003093//regulation of glomerular filtration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0030036//actin cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0048041//focal adhesion assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0080135//regulation of cellular response to stress;GO:1904950//negative regulation of establishment of protein localization;GO:1904951//positive regulation of establishment of protein localization	--
ENSG00000103653	16.722	19.496	19.14	19.791	19.302	23.482	790	882	629	674	749	783	CSK	C-terminal Src kinase [Source:HGNC Symbol;Acc:HGNC:2444]	Human Diseases	Infectious disease: bacterial	ko05120//Epithelial cell signaling in Helicobacter pylori infection	K05728	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070064//proline-rich region binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031295//T cell costimulation;GO:0032715//negative regulation of interleukin-6 production;GO:0033673//negative regulation of kinase activity;GO:0034332//adherens junction organization;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0043406//positive regulation of MAP kinase activity;GO:0045779//negative regulation of bone resorption;GO:0046777//protein autophosphorylation;GO:0048709//oligodendrocyte differentiation;GO:0050765//negative regulation of phagocytosis;GO:0050852//T cell receptor signaling pathway;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071375//cellular response to peptide hormone stimulus	--
ENSG00000103657	11.682	14.316	10.989	8.449	12.324	10.966	2184	2025	1520	1012	1655	1273	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:HGNC Symbol;Acc:HGNC:4867]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10594	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0010507//negative regulation of autophagy;GO:0016567//protein ubiquitination;GO:0021702//cerebellar Purkinje cell differentiation;GO:0031175//neuron projection development;GO:0050790//regulation of catalytic activity;GO:0050885//neuromuscular process controlling balance	--
ENSG00000103671	6.419	6.773	6.416	4.951	5.585	6.455	267	279	185	152	197	191	TRIP4	thyroid hormone receptor interactor 4 [Source:HGNC Symbol;Acc:HGNC:12310]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0099053//activating signal cointegrator 1 complex	GO:0002020//protease binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016922//nuclear receptor binding;GO:0019901//protein kinase binding;GO:0030331//estrogen receptor binding;GO:0035035//histone acetyltransferase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0045661//regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072344//rescue of stalled ribosome;GO:1901998//toxin transport;GO:1990116//ribosome-associated ubiquitin-dependent protein catabolic process"	--
ENSG00000103707	4.475	4.907	4.37	3.059	4.423	4.554	155	164	111	81	130	120	MTFMT	mitochondrial methionyl-tRNA formyltransferase [Source:HGNC Symbol;Acc:HGNC:29666]	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00670//One carbon pool by folate	K00604;K00604;K00604	GO:0005739//mitochondrion	"GO:0003824//catalytic activity;GO:0004479//methionyl-tRNA formyltransferase activity;GO:0016740//transferase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity"	GO:0006412//translation;GO:0006413//translational initiation;GO:0009058//biosynthetic process;GO:0071951//conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	--
ENSG00000103710	11.548	13.051	8.21	4.208	5.641	3.613	594	660	304	152	249	126	RASL12	RAS like family 12 [Source:HGNC Symbol;Acc:HGNC:30289]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0007165//signal transduction	--
ENSG00000103723	0.474	0.175	0.298	0.186	0.316	0.646	18	10	12	8	18	18	AP3B2	adaptor related protein complex 3 subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:567]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12397	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030123//AP-3 adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0097708//intracellular vesicle;GO:1904115//axon cytoplasm	GO:0030276//clathrin binding	"GO:0006886//intracellular protein transport;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016183//synaptic vesicle coating;GO:0016192//vesicle-mediated transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0036465//synaptic vesicle recycling;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport"	--
ENSG00000103740	0.049	0.048	0.016	0.026	0.228	0.067	6.32	6.24	1.57	1	5.55	6.27	ACSBG1	acyl-CoA synthetase bubblegum family member 1 [Source:HGNC Symbol;Acc:HGNC:29567]	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko00061//Fatty acid biosynthesis	K15013;K15013;K15013;K15013;K15013;K15013	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001552//ovarian follicle atresia;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042552//myelination;GO:0042759//long-chain fatty acid biosynthetic process;GO:0051384//response to glucocorticoid	--
ENSG00000103742	7.342	7.448	6.001	4.132	4.941	3.738	969	988	585	404	551	359	IGDCC4	immunoglobulin superfamily DCC subclass member 4 [Source:HGNC Symbol;Acc:HGNC:13770]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0098609//cell-cell adhesion	--
ENSG00000103769	103.006	89.963	89.846	95.541	94.63	104.948	2539	2224	1657	1643	1897	1842	RAB11A	"RAB11A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9760]"	Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Transport and catabolism;Infectious disease: viral;Digestive system;Excretory system;Excretory system	ko04144//Endocytosis;ko05164//Influenza A;ko04972//Pancreatic secretion;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04962//Vasopressin-regulated water reabsorption	K07904;K07904;K07904;K07904;K07904	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005813//centrosome;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030424//axon;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098837//postsynaptic recycling endosome;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0019905//syntaxin binding;GO:0031489//myosin V binding	"GO:0006887//exocytosis;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0010634//positive regulation of epithelial cell migration;GO:0010796//regulation of multivesicular body size;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030953//astral microtubule organization;GO:0031175//neuron projection development;GO:0032402//melanosome transport;GO:0032465//regulation of cytokinesis;GO:0034394//protein localization to cell surface;GO:0036258//multivesicular body assembly;GO:0045773//positive regulation of axon extension;GO:0048227//plasma membrane to endosome transport;GO:0051650//establishment of vesicle localization;GO:0060627//regulation of vesicle-mediated transport;GO:0072594//establishment of protein localization to organelle;GO:0072659//protein localization to plasma membrane;GO:0090150//establishment of protein localization to membrane;GO:0090307//mitotic spindle assembly;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0150093//amyloid-beta clearance by transcytosis;GO:1990182//exosomal secretion"	--
ENSG00000103811	158.875	163.798	145.092	181.688	169.119	177.012	4272	4409	2866	3634	3838	3443	CTSH	cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K01366;K01366	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0097208//alveolar lamellar body;GO:0097486//multivesicular body lumen;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0016787//hydrolase activity;GO:0030108//HLA-A specific activating MHC class I receptor activity;GO:0070324//thyroid hormone binding	GO:0001656//metanephros development;GO:0001913//T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002764//immune response-regulating signaling pathway;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010813//neuropeptide catabolic process;GO:0010815//bradykinin catabolic process;GO:0010952//positive regulation of peptidase activity;GO:0019882//antigen processing and presentation;GO:0030335//positive regulation of cell migration;GO:0031638//zymogen activation;GO:0031648//protein destabilization;GO:0032526//response to retinoic acid;GO:0033619//membrane protein proteolysis;GO:0043066//negative regulation of apoptotic process;GO:0043129//surfactant homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0060448//dichotomous subdivision of terminal units involved in lung branching;GO:0070371//ERK1 and ERK2 cascade;GO:0097067//cellular response to thyroid hormone stimulus;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000103852	13.338	11.058	12.531	9.773	10.96	11.503	537	444	395	283	372	307	TTC23	tetratricopeptide repeat domain 23 [Source:HGNC Symbol;Acc:HGNC:25730]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000103855	82.127	94.011	89.708	75.234	83.784	75.148	5421	6024	4289	3666	4673	3621	CD276	CD276 molecule [Source:HGNC Symbol;Acc:HGNC:19137]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06746	GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0002376//immune system process;GO:0032729//positive regulation of interferon-gamma production;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0050776//regulation of immune response;GO:0050852//T cell receptor signaling pathway	--
ENSG00000103876	10.129	10.358	10.405	14.71	10.697	8.526	309	332	256	294	253	193	FAH	fumarylacetoacetate hydrolase [Source:HGNC Symbol;Acc:HGNC:3579]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K01555;K01555	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004334//fumarylacetoacetase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006527//arginine catabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0006572//tyrosine catabolic process;GO:0006629//lipid metabolic process;GO:0009072//aromatic amino acid family metabolic process;GO:1902000//homogentisate catabolic process	--
ENSG00000103888	1.795	1.552	0.515	0.694	0.956	1.373	269	234	57	77	121	108	CEMIP	cell migration inducing hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:29213]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0045334//clathrin-coated endocytic vesicle	"GO:0004415//hyalurononglucosaminidase activity;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0032050//clathrin heavy chain binding;GO:0046923//ER retention sequence binding"	GO:0007605//sensory perception of sound;GO:0008152//metabolic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0030213//hyaluronan biosynthetic process;GO:0030214//hyaluronan catabolic process;GO:0030335//positive regulation of cell migration;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0090314//positive regulation of protein targeting to membrane;GO:1900020//positive regulation of protein kinase C activity	--
ENSG00000103932	8.822	8.89	10.086	12.004	10.519	8.563	857	857	644	675	850	605	RPAP1	RNA polymerase II associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24567]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006366//transcription by RNA polymerase II	--
ENSG00000103942	75.957	74.408	67.478	58.241	55.497	61.023	4520	4284	2880	2508	2759	2648	HOMER2	homer scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:17513]	Environmental Information Processing;Organismal Systems	Signal transduction;Nervous system	ko04068//FoxO signaling pathway;ko04724//Glutamatergic synapse	K15010;K15010	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0043229//intracellular organelle;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0030160//synaptic receptor adaptor activity;GO:0035256//G protein-coupled glutamate receptor binding	GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0032703//negative regulation of interleukin-2 production;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0048148//behavioral response to cocaine;GO:0048875//chemical homeostasis within a tissue;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000103966	4.783	4.578	6.078	5.725	5.126	4.751	635	611	596	563	575	459	EHD4	EH domain containing 4 [Source:HGNC Symbol;Acc:HGNC:3245]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12477	GO:0005634//nucleus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0006907//pinocytosis;GO:0016197//endosomal transport;GO:0030100//regulation of endocytosis;GO:0032456//endocytic recycling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051260//protein homooligomerization;GO:0060271//cilium assembly;GO:0071363//cellular response to growth factor stimulus;GO:0072659//protein localization to plasma membrane	--
ENSG00000103978	28.52	27.638	26.584	23.268	26.042	24.989	1629.12	1599.17	1157.11	981.82	1185.74	1001.8	TMEM87A	transmembrane protein 87A [Source:HGNC Symbol;Acc:HGNC:24522]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	-	"GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000103994	96.075	77.522	76.984	57.351	63.461	65.46	18821.96	15727	11355	8425	10565	9274	ZNF106	zinc finger protein 106 [Source:HGNC Symbol;Acc:HGNC:12886]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0008286//insulin receptor signaling pathway	--
ENSG00000103995	0.489	0.337	0.264	0.11	0.328	0.557	54	38	22	7	32	28	CEP152	centrosomal protein 152 [Source:HGNC Symbol;Acc:HGNC:29298]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0098536//deuterosome;GO:0120098//procentriole;GO:0120099//procentriole replication complex	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007099//centriole replication;GO:0030030//cell projection organization;GO:0051298//centrosome duplication;GO:0098535//de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	--
ENSG00000104043	0.105	0.101	0.149	0.054	0.027	0.058	11	12	13	3	2	5	ATP8B4	ATPase phospholipid transporting 8B4 (putative) [Source:HGNC Symbol;Acc:HGNC:13536]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140326//ATPase-coupled intramembrane lipid transporter activity	GO:0006869//lipid transport;GO:0007030//Golgi organization;GO:0015914//phospholipid transport;GO:0034204//lipid translocation;GO:0045332//phospholipid translocation	--
ENSG00000104044	14.103	14.254	15.129	15.291	17.665	15.925	896	929	724	734	956	749	OCA2	OCA2 melanosomal transmembrane protein [Source:HGNC Symbol;Acc:HGNC:8101]	-	-	-	-	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033162//melanosome membrane	GO:0005215//transporter activity;GO:0005302//L-tyrosine transmembrane transporter activity;GO:0005515//protein binding	GO:0006726//eye pigment biosynthetic process;GO:0007286//spermatid development;GO:0008283//cell population proliferation;GO:0015828//tyrosine transport;GO:0030318//melanocyte differentiation;GO:0042438//melanin biosynthetic process;GO:0043473//pigmentation;GO:0048066//developmental pigmentation;GO:0055085//transmembrane transport	--
ENSG00000104047	12.308	11.229	8.571	7.823	9.873	9.3	391	397	225	194	256	236	DTWD1	DTW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30926]	-	-	-	-	GO:0005634//nucleus	GO:0016432//tRNA-uridine aminocarboxypropyltransferase activity;GO:0016740//transferase activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing	--
ENSG00000104055	0	0	0	0	0	0	0	0	0	0	0	0	TGM5	transglutaminase 5 [Source:HGNC Symbol;Acc:HGNC:11781]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	GO:0006464//cellular protein modification process;GO:0008544//epidermis development;GO:0018149//peptide cross-linking	--
ENSG00000104059	0.651	0.879	0.842	1.246	1.035	0.868	67	91	64	95	90	65	FAM189A1	family with sequence similarity 189 member A1 [Source:HGNC Symbol;Acc:HGNC:29075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000104064	7.165	5.074	5.198	4.299	4.055	6.386	319	246	179	151	150	203	GABPB1	GA binding protein transcription factor subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4074]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0000976//transcription cis-regulatory region binding;GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000104067	34.673	29.633	27.356	22.103	24.512	28.682	3930	3192	2221	1779	2448	2402	TJP1	tight junction protein 1 [Source:HGNC Symbol;Acc:HGNC:11827]	Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases	Infectious disease: bacterial;Cellular community - eukaryotes;Cellular community - eukaryotes;Cellular community - eukaryotes;Infectious disease: bacterial;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko04540//Gap junction;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection	K05701;K05701;K05701;K05701;K05701;K05701	GO:0002102//podosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005921//gap junction;GO:0005923//bicellular tight junction;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0046581//intercellular canaliculus;GO:0070160//tight junction	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0071253//connexin binding	GO:0001825//blastocyst formation;GO:0007043//cell-cell junction assembly;GO:0007605//sensory perception of sound;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0030335//positive regulation of cell migration;GO:0031032//actomyosin structure organization;GO:0032496//response to lipopolysaccharide;GO:0034334//adherens junction maintenance;GO:0035633//maintenance of blood-brain barrier;GO:0043066//negative regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0045216//cell-cell junction organization;GO:0045471//response to ethanol;GO:0051493//regulation of cytoskeleton organization;GO:0051497//negative regulation of stress fiber assembly;GO:0071000//response to magnetism;GO:0071333//cellular response to glucose stimulus;GO:0071896//protein localization to adherens junction;GO:0090557//establishment of endothelial intestinal barrier;GO:0098609//cell-cell adhesion;GO:0150105//protein localization to cell-cell junction;GO:1901888//regulation of cell junction assembly;GO:1902396//protein localization to bicellular tight junction;GO:1903672//positive regulation of sprouting angiogenesis;GO:1905605//positive regulation of blood-brain barrier permeability;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:2000250//negative regulation of actin cytoskeleton reorganization;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000104081	83.969	90.714	90.157	64.544	74.256	72.326	7318	7591	5689	4116	5126	4500	BMF	Bcl2 modifying factor [Source:HGNC Symbol;Acc:HGNC:24132]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17460	GO:0001669//acrosomal vesicle;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016459//myosin complex	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0010507//negative regulation of autophagy;GO:0031334//positive regulation of protein-containing complex assembly;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0043276//anoikis;GO:0090200//positive regulation of release of cytochrome c from mitochondria	--
ENSG00000104093	6.314	3.899	3.878	2.874	3.781	4.394	1390	826	627	469	672	665	DMXL2	Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K24155	GO:0005615//extracellular space;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043291//RAVE complex;GO:0045202//synapse;GO:0098992//neuronal dense core vesicle	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007035//vacuolar acidification	--
ENSG00000104112	0	0	0	0	0	0	0	0	0	0	0	0	SCG3	secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0033366//protein localization to secretory granule	--
ENSG00000104129	10.297	7.619	15.235	10.208	8.115	9.565	184.42	144.83	141.68	112.51	127.55	122.74	DNAJC17	DnaJ heat shock protein family (Hsp40) member C17 [Source:HGNC Symbol;Acc:HGNC:25556]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:1901998//toxin transport	--
ENSG00000104131	20.702	23.184	17.542	17.979	21.027	20.598	830	848	484	491	606	547	EIF3J	eukaryotic translation initiation factor 3 subunit J [Source:HGNC Symbol;Acc:HGNC:3270]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex	GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000104133	12.532	9.82	10.434	8.147	9.599	8.51	1848	1506	1164	916	1272	969	SPG11	"SPG11 vesicle trafficking associated, spatacsin [Source:HGNC Symbol;Acc:HGNC:11226]"	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K19026;K19026	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006606//protein import into nucleus;GO:0007040//lysosome organization;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0007613//memory;GO:0008088//axo-dendritic transport;GO:0021957//corticospinal tract morphogenesis;GO:0033344//cholesterol efflux;GO:0048489//synaptic vesicle transport;GO:0048675//axon extension;GO:0048741//skeletal muscle fiber development;GO:0051402//neuron apoptotic process;GO:0061744//motor behavior;GO:0090389//phagosome-lysosome fusion involved in apoptotic cell clearance;GO:0090659//walking behavior;GO:0097049//motor neuron apoptotic process;GO:1905037//autophagosome organization;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000104140	0.058	0	0.158	0.197	0.138	0.12	2	0	4	5	4	3	RHOV	ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0016477//cell migration;GO:0030031//cell projection assembly;GO:0032488//Cdc42 protein signal transduction	--
ENSG00000104142	25.28	28.957	30.24	34.448	33.193	32.108	1979	2290	1741	1995	2254	1806	VPS18	VPS18 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:15972]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20181	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005884//actin filament;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030897//HOPS complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0033263//CORVET complex;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006886//intracellular protein transport;GO:0006904//vesicle docking involved in exocytosis;GO:0006914//autophagy;GO:0007032//endosome organization;GO:0007033//vacuole organization;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016567//protein ubiquitination;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly;GO:0046718//viral entry into host cell;GO:0046907//intracellular transport;GO:0048284//organelle fusion;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000104147	0.923	0.919	0.924	0.379	0.475	0.705	23	23	17	7	10	12.77	OIP5	Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0010369//chromocenter;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle"	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007154//cell communication;GO:0034080//CENP-A containing nucleosome assembly;GO:0051301//cell division	--
ENSG00000104154	6.354	4.864	4.333	3.543	4.085	4.865	937	721	472	387	509	522	SLC30A4	solute carrier family 30 member 4 [Source:HGNC Symbol;Acc:HGNC:11015]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0009636//response to toxic substance;GO:0010043//response to zinc ion;GO:0055069//zinc ion homeostasis;GO:0055085//transmembrane transport;GO:0061088//regulation of sequestering of zinc ion;GO:0071577//zinc ion transmembrane transport	--
ENSG00000104164	22.453	20.288	19.288	20.392	17.728	19.01	1375	1239	886	821	816	853	BLOC1S6	biogenesis of lysosomal organelles complex 1 subunit 6 [Source:HGNC Symbol;Acc:HGNC:8549]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex;GO:0031201//SNARE complex;GO:0098793//presynapse;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051015//actin filament binding	GO:0007596//blood coagulation;GO:0008089//anterograde axonal transport;GO:0016081//synaptic vesicle docking;GO:0030318//melanocyte differentiation;GO:0031175//neuron projection development;GO:0032402//melanosome transport;GO:0032438//melanosome organization;GO:0032816//positive regulation of natural killer cell activation;GO:0033299//secretion of lysosomal enzymes;GO:0035646//endosome to melanosome transport;GO:0043473//pigmentation;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport;GO:0050942//positive regulation of pigment cell differentiation;GO:0061025//membrane fusion	--
ENSG00000104177	19.885	16.51	19.821	16.083	17.3	20.479	1267.91	1077.77	880.68	781.93	903.82	917.82	MYEF2	myelin expression factor 2 [Source:HGNC Symbol;Acc:HGNC:17940]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071014//post-mRNA release spliceosomal complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0014902//myotube differentiation;GO:0030182//neuron differentiation;GO:2000815//regulation of mRNA stability involved in response to oxidative stress	Others
ENSG00000104205	37.468	24.781	29.281	27.728	30.923	32.72	2209.19	1769.21	1636.27	1601.33	1902.33	1726.39	SGK3	serum/glucocorticoid regulated kinase family member 3 [Source:HGNC Symbol;Acc:HGNC:10812]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04068//FoxO signaling pathway	K13304;K13304	GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015459//potassium channel regulator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017080//sodium channel regulator activity;GO:0017081//chloride channel regulator activity;GO:0035091//phosphatidylinositol binding;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030334//regulation of cell migration;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0051090//regulation of DNA-binding transcription factor activity	--
ENSG00000104213	4.743	5.891	5.462	3.182	3.846	3.547	139	174	113	69	97	71	PDGFRL	platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0004992//platelet activating factor receptor activity;GO:0005019//platelet-derived growth factor beta-receptor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008150//biological_process;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000104218	2.027	1.31	1.715	1.028	1.792	1.095	133	112	84	44	88	67	CSPP1	centrosome and spindle pole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:26193]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0032467//positive regulation of cytokinesis;GO:0051781//positive regulation of cell division	--
ENSG00000104219	16.144	11.125	10.744	11.804	9.835	10.369	1690	1374	975	749	1021	927	ZDHHC2	zinc finger DHHC-type palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:18469]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0055038//recycling endosome membrane;GO:0098837//postsynaptic recycling endosome	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0042803//protein homodimerization activity;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0016188//synaptic vesicle maturation;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0022407//regulation of cell-cell adhesion;GO:0042176//regulation of protein catabolic process;GO:0044267//cellular protein metabolic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0072659//protein localization to plasma membrane;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1903076//regulation of protein localization to plasma membrane;GO:1903539//protein localization to postsynaptic membrane;GO:1904719//positive regulation of AMPA glutamate receptor clustering;GO:1905751//positive regulation of endosome to plasma membrane protein transport	--
ENSG00000104221	4.724	4.166	5.517	4.96	4.527	6.327	219.13	222.35	196.83	182.26	193.75	244.45	BRF2	BRF2 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:17298]	-	-	-	-	GO:0000126//transcription factor TFIIIB complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0097550//transcription preinitiation complex	GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0017025//TBP-class protein binding;GO:0046872//metal ion binding	"GO:0006352//DNA-templated transcription, initiation;GO:0006359//regulation of transcription by RNA polymerase III;GO:0034599//cellular response to oxidative stress;GO:0070897//transcription preinitiation complex assembly"	--
ENSG00000104228	3.93	4.423	5.134	4.046	4.646	4.602	336	380	329	260	335	285	TRIM35	tripartite motif containing 35 [Source:HGNC Symbol;Acc:HGNC:16285]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045930//negative regulation of mitotic cell cycle	--
ENSG00000104231	8.915	7.4	7.429	6.962	9.695	11.491	253	230	156	169	226	214	ZFAND1	zinc finger AN1-type containing 1 [Source:HGNC Symbol;Acc:HGNC:25858]	-	-	-	-	GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0070628//proteasome binding	GO:0035617//stress granule disassembly;GO:0090316//positive regulation of intracellular protein transport;GO:1903843//cellular response to arsenite ion	--
ENSG00000104237	0.033	0	0.036	0.036	0.063	0.018	3	0	2	2	4	1	RP1	RP1 axonemal microtubule associated [Source:HGNC Symbol;Acc:HGNC:10263]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097733//photoreceptor cell cilium	GO:0005515//protein binding;GO:0008017//microtubule binding	"GO:0007601//visual perception;GO:0007603//phototransduction, visible light;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0035556//intracellular signal transduction;GO:0035845//photoreceptor cell outer segment organization;GO:0042461//photoreceptor cell development;GO:0045494//photoreceptor cell maintenance;GO:0046548//retinal rod cell development;GO:0046549//retinal cone cell development;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:0060042//retina morphogenesis in camera-type eye;GO:0071482//cellular response to light stimulus;GO:1902857//positive regulation of non-motile cilium assembly"	--
ENSG00000104267	19.148	14.78	20.277	15	14.601	21.524	606	466	467	355	393	501	CA2	carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Excretory system;Excretory system;Energy metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04976//Bile secretion;ko04971//Gastric acid secretion;ko04964//Proximal tubule bicarbonate reclamation;ko04966//Collecting duct acid secretion;ko00910//Nitrogen metabolism	K18245;K18245;K18245;K18245;K18245;K18245;K18245	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043209//myelin sheath;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0004064//arylesterase activity;GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	"GO:0002009//morphogenesis of an epithelium;GO:0006730//one-carbon metabolic process;GO:0015670//carbon dioxide transport;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032849//positive regulation of cellular pH reduction;GO:0038166//angiotensin-activated signaling pathway;GO:0044070//regulation of anion transport;GO:0046903//secretion;GO:0051453//regulation of intracellular pH;GO:2001150//positive regulation of dipeptide transmembrane transport;GO:2001225//regulation of chloride transport"	--
ENSG00000104290	5.403	3.684	4.099	3.57	4.399	4.066	1542	1056	830	647	844	845	FZD3	frizzled class receptor 3 [Source:HGNC Symbol;Acc:HGNC:4041]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Development and regeneration;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329;K02329	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032433//filopodium tip;GO:0043025//neuronal cell body;GO:0045177//apical part of cell;GO:0048786//presynaptic active zone	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity	"GO:0001736//establishment of planar polarity;GO:0001764//neuron migration;GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0002052//positive regulation of neuroblast proliferation;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0007420//brain development;GO:0009410//response to xenobiotic stimulus;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030901//midbrain development;GO:0033278//cell proliferation in midbrain;GO:0036342//post-anal tail morphogenesis;GO:0036514//dopaminergic neuron axon guidance;GO:0036515//serotonergic neuron axon guidance;GO:0042472//inner ear morphogenesis;GO:0045976//negative regulation of mitotic cell cycle, embryonic;GO:0051602//response to electrical stimulus;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061549//sympathetic ganglion development;GO:0071679//commissural neuron axon guidance;GO:1900118//negative regulation of execution phase of apoptosis;GO:1904693//midbrain morphogenesis;GO:1904938//planar cell polarity pathway involved in axon guidance"	--
ENSG00000104299	11.915	13.735	13.04	12.791	11.746	13.624	626	613	464	479	517	504	INTS9	integrator complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:25592]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing	--
ENSG00000104312	5.372	5.436	6.461	3.476	4.238	4.466	240	236	176	122	177	156	RIPK2	receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Nervous system	ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04621//NOD-like receptor signaling pathway;ko04722//Neurotrophin signaling pathway	K08846;K08846;K08846;K08846;K08846	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031982//vesicle;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030274//LIM domain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0050700//CARD domain binding;GO:0089720//caspase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010942//positive regulation of cell death;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031398//positive regulation of protein ubiquitination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032722//positive regulation of chemokine production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0033091//positive regulation of immature T cell proliferation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0042098//T cell proliferation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050830//defense response to Gram-positive bacterium;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070427//nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0070555//response to interleukin-1;GO:0070671//response to interleukin-12;GO:0070673//response to interleukin-18;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071224//cellular response to peptidoglycan;GO:0071225//cellular response to muramyl dipeptide;GO:0071310//cellular response to organic substance;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1904417//positive regulation of xenophagy	--
ENSG00000104313	0.787	0.349	0.149	0.109	0.273	0.104	31	28	9	7	15	5	EYA1	EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15616	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0007501//mesodermal cell fate specification;GO:0007605//sensory perception of sound;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010212//response to ionizing radiation;GO:0014706//striated muscle tissue development;GO:0016576//histone dephosphorylation;GO:0016925//protein sumoylation;GO:0030154//cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035909//aorta morphogenesis;GO:0042471//ear morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042473//outer ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0045165//cell fate commitment;GO:0045664//regulation of neuron differentiation;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048665//neuron fate specification;GO:0048704//embryonic skeletal system morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0048856//anatomical structure development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060037//pharyngeal system development;GO:0071599//otic vesicle development;GO:0071600//otic vesicle morphogenesis;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0090103//cochlea morphogenesis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000104320	5.728	5.32	4.878	3.085	5.066	3.364	549	502	304	204	333	212	NBN	nibrin [Source:HGNC Symbol;Acc:HGNC:7652]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04218//Cellular senescence;ko03440//Homologous recombination	K10867;K10867	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016605//PML body;GO:0030870//Mre11 complex;GO:0035861//site of double-strand break;GO:0042405//nuclear inclusion body;GO:0043229//intracellular organelle;GO:0070533//BRCA1-C complex;GO:0098687//chromosomal region"	GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000077//DNA damage checkpoint signaling;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0000729//DNA double-strand break processing;GO:0001701//in utero embryonic development;GO:0001832//blastocyst growth;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007093//mitotic cell cycle checkpoint signaling;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0008283//cell population proliferation;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0031860//telomeric 3' overhang formation;GO:0031954//positive regulation of protein autophosphorylation;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0033674//positive regulation of kinase activity;GO:0035825//homologous recombination;GO:0044818//mitotic G2/M transition checkpoint;GO:0045190//isotype switching;GO:0050885//neuromuscular process controlling balance;GO:0050896//response to stimulus;GO:0051321//meiotic cell cycle;GO:0051726//regulation of cell cycle;GO:0090656//t-circle formation;GO:0090737//telomere maintenance via telomere trimming;GO:0097193//intrinsic apoptotic signaling pathway;GO:0110025//DNA strand resection involved in replication fork processing;GO:1904354//negative regulation of telomere capping"	--
ENSG00000104321	0	0	0	0	0	0	0	0	0	0	0	0	TRPA1	transient receptor potential cation channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:497]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04984	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032421//stereocilium bundle	GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015267//channel activity;GO:0015278//calcium-release channel activity;GO:0042802//identical protein binding;GO:0097604//temperature-gated cation channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0009409//response to cold;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0014070//response to organic cyclic compound;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0042542//response to hydrogen peroxide;GO:0048265//response to pain;GO:0050896//response to stimulus;GO:0050955//thermoception;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0050968//detection of chemical stimulus involved in sensory perception of pain;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0070301//cellular response to hydrogen peroxide;GO:0070588//calcium ion transmembrane transport;GO:0071310//cellular response to organic substance	--
ENSG00000104324	47.455	53.079	49.094	53.425	45.562	55.118	1779	1952	1409	1506	1505	1594	CPQ	carboxypeptidase Q [Source:HGNC Symbol;Acc:HGNC:16910]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity	GO:0006508//proteolysis;GO:0006590//thyroid hormone generation;GO:0042246//tissue regeneration;GO:0043171//peptide catabolic process	--
ENSG00000104325	22.087	25.535	22.206	19.506	16.371	19.259	506	530	370	295	296	298	DECR1	"2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1902494//catalytic complex	"GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0070402//NADPH binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000104327	0.019	0	0.044	0	0	0	1	0	1	0	0	0	CALB1	calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434]	Organismal Systems	Excretory system	ko04961//Endocrine and other factor-regulated calcium reabsorption	K14757	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon;GO:0030425//dendrite;GO:0032420//stereocilium;GO:0032437//cuticular plate;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol	GO:0005499//vitamin D binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0099534//calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration;GO:0099567//calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration	GO:0007611//learning or memory;GO:0007614//short-term memory;GO:0007616//long-term memory;GO:0007626//locomotory behavior;GO:0010842//retina layer formation;GO:0035502//metanephric part of ureteric bud development;GO:0048167//regulation of synaptic plasticity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055074//calcium ion homeostasis;GO:0060041//retina development in camera-type eye;GO:0071310//cellular response to organic substance;GO:0072205//metanephric collecting duct development;GO:0072221//metanephric distal convoluted tubule development;GO:0072286//metanephric connecting tubule development;GO:0090102//cochlea development;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1900271//regulation of long-term synaptic potentiation	--
ENSG00000104331	17.145	18.105	16.109	15.234	16.672	17.86	2511	2511.14	1756	1563	1854	1761	BPNT2	"3'(2'), 5'-bisphosphate nucleotidase 2 [Source:HGNC Symbol;Acc:HGNC:26019]"	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Energy metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00920//Sulfur metabolism	K15759;K15759;K15759	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0032588//trans-Golgi network membrane	"GO:0008254//3'-nucleotidase activity;GO:0008441//3'(2'),5'-bisphosphate nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0097657//3',5'-nucleotide bisphosphate phosphatase activity"	GO:0001501//skeletal system development;GO:0001958//endochondral ossification;GO:0002063//chondrocyte development;GO:0009791//post-embryonic development;GO:0030204//chondroitin sulfate metabolic process;GO:0042733//embryonic digit morphogenesis;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation	--
ENSG00000104332	455.266	456.905	544.499	395.791	429.971	424.4	41924	42282	37089	27077	33493	28411	SFRP1	secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K02166	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004197//cysteine-type endopeptidase activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0017147//Wnt-protein binding;GO:0042802//identical protein binding	"GO:0001649//osteoblast differentiation;GO:0001657//ureteric bud development;GO:0001756//somitogenesis;GO:0001843//neural tube closure;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006508//proteolysis;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009267//cellular response to starvation;GO:0009410//response to xenobiotic stimulus;GO:0009950//dorsal/ventral axis specification;GO:0009952//anterior/posterior pattern specification;GO:0010564//regulation of cell cycle process;GO:0010629//negative regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010975//regulation of neuron projection development;GO:0014034//neural crest cell fate commitment;GO:0014070//response to organic cyclic compound;GO:0016055//Wnt signaling pathway;GO:0021915//neural tube development;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030279//negative regulation of ossification;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0033689//negative regulation of osteoblast proliferation;GO:0035019//somatic stem cell population maintenance;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043508//negative regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0044345//stromal-epithelial cell signaling involved in prostate gland development;GO:0045578//negative regulation of B cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045765//regulation of angiogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046546//development of primary male sexual characteristics;GO:0046676//negative regulation of insulin secretion;GO:0046851//negative regulation of bone remodeling;GO:0048147//negative regulation of fibroblast proliferation;GO:0048546//digestive tract morphogenesis;GO:0048856//anatomical structure development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060218//hematopoietic stem cell differentiation;GO:0060346//bone trabecula formation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0071305//cellular response to vitamin D;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071391//cellular response to estrogen stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071456//cellular response to hypoxia;GO:0071481//cellular response to X-ray;GO:0071504//cellular response to heparin;GO:0071542//dopaminergic neuron differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071773//cellular response to BMP stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090175//regulation of establishment of planar polarity;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0090246//convergent extension involved in somitogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1904956//regulation of midbrain dopaminergic neuron differentiation;GO:2000041//negative regulation of planar cell polarity pathway involved in axis elongation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:2000054//negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification;GO:2000080//negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation;GO:2000270//negative regulation of fibroblast apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000104341	266.017	270.495	256.092	258.472	267.849	255.27	13454	13706	9552	9660	11414	9353	LAPTM4B	lysosomal protein transmembrane 4 beta [Source:HGNC Symbol;Acc:HGNC:13646]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12387	"GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0042995//cell projection;GO:0097487//multivesicular body, internal vesicle"	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0097001//ceramide binding;GO:1902936//phosphatidylinositol bisphosphate binding	GO:0007032//endosome organization;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0097213//regulation of lysosomal membrane permeability;GO:1905166//negative regulation of lysosomal protein catabolic process;GO:1905671//regulation of lysosome organization	--
ENSG00000104343	9.871	8.283	7.396	7.247	7.767	9.557	666.96	571.34	378.95	356.17	444.26	467.59	UBE2W	ubiquitin conjugating enzyme E2 W [Source:HGNC Symbol;Acc:HGNC:25616]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10688	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0071218//cellular response to misfolded protein	--
ENSG00000104356	1.583	1.875	2.724	1.154	1.412	2.629	99	133	98	84	93	78	POP1	"POP1 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30129]"	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K01164	GO:0000172//ribonuclease MRP complex;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0008033//tRNA processing;GO:0016078//tRNA catabolic process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000104361	4.482	3.55	2.343	4.041	4.257	4.294	412	328	158	276	331	286	NIPAL2	NIPA like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25854]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015095//magnesium ion transmembrane transporter activity	GO:0015693//magnesium ion transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000104365	6.038	6.774	6.429	6.42	7.239	6.623	419	450	327	314	386	328	IKBKB	inhibitor of nuclear factor kappa B kinase subunit beta [Source:HGNC Symbol;Acc:HGNC:5960]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Cancer: overview;Endocrine and metabolic disease;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Cardiovascular disease;Signal transduction;Development and regeneration;Nervous system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: specific types;Immune system;Cancer: overview;Immune system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04068//FoxO signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05221//Acute myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04623//Cytosolic DNA-sensing pathway;ko04930//Type II diabetes mellitus;ko01523//Antifolate resistance	K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209;K07209	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008385//IkappaB kinase complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0035631//CD40 receptor complex;GO:0045121//membrane raft	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008384//IkappaB kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity;GO:1990459//transferrin receptor binding	"GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007252//I-kappaB phosphorylation;GO:0009615//response to virus;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030866//cortical actin cytoskeleton organization;GO:0031399//regulation of protein modification process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042325//regulation of phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050852//T cell receptor signaling pathway;GO:0050896//response to stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051403//stress-activated MAPK cascade;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0072659//protein localization to plasma membrane;GO:1903140//regulation of establishment of endothelial barrier;GO:1903347//negative regulation of bicellular tight junction assembly"	--
ENSG00000104368	16.969	11.602	4.625	5.924	9.75	6.421	879	628	185	235	447	249	PLAT	"plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051]"	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Cardiovascular disease;Cancer: specific types;Immune system	ko05202//Transcriptional misregulation in cancer;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko05215//Prostate cancer;ko04610//Complement and coagulation cascades	K01343;K01343;K01343;K01343;K01343	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0097180//serine protease inhibitor complex;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098992//neuronal dense core vesicle;GO:0099544//perisynaptic space	GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0051219//phosphoprotein binding	"GO:0001666//response to hypoxia;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0010757//negative regulation of plasminogen activation;GO:0014909//smooth muscle cell migration;GO:0031639//plasminogen activation;GO:0035249//synaptic transmission, glutamatergic;GO:0042060//wound healing;GO:0042730//fibrinolysis;GO:0045861//negative regulation of proteolysis;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0051591//response to cAMP;GO:0051918//negative regulation of fibrinolysis;GO:0060279//positive regulation of ovulation;GO:0060468//prevention of polyspermy;GO:0070542//response to fatty acid;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:0099183//trans-synaptic signaling by BDNF, modulating synaptic transmission"	--
ENSG00000104369	0.252	0.651	0.381	0.584	0.663	0.52	24	38	13	20	26	20	JPH1	junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030314//junctional membrane complex;GO:0033017//sarcoplasmic reticulum membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0007517//muscle organ development;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060402//calcium ion transport into cytosol	--
ENSG00000104371	0	0	0	0	0	0	0	0	0	0	0	0	DKK4	dickkopf WNT signaling pathway inhibitor 4 [Source:HGNC Symbol;Acc:HGNC:2894]	Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway	K02165;K02165;K02165	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0039706//co-receptor binding;GO:0048019//receptor antagonist activity	GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0061170//negative regulation of hair follicle placode formation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000104375	7.53	5.696	6.62	4.204	5.902	6.535	442	336	269	183	293	279	STK3	serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K04412;K04412;K04412	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001841//neural tube formation;GO:0003157//endocardium development;GO:0006468//protein phosphorylation;GO:0006606//protein import into nucleus;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0032092//positive regulation of protein binding;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0045600//positive regulation of fat cell differentiation;GO:0046330//positive regulation of JNK cascade;GO:0046621//negative regulation of organ growth;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051262//protein tetramerization;GO:0051897//positive regulation of protein kinase B signaling;GO:0060215//primitive hemopoiesis;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060800//regulation of cell differentiation involved in embryonic placenta development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097284//hepatocyte apoptotic process;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000104381	2.887	3.422	4.545	3.148	5.227	2.856	181	202	169	145	216	125	GDAP1	ganglioside induced differentiation associated protein 1 [Source:HGNC Symbol;Acc:HGNC:15968]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0005515//protein binding	GO:0000266//mitochondrial fission;GO:0006626//protein targeting to mitochondrion;GO:0006749//glutathione metabolic process;GO:0008053//mitochondrial fusion;GO:0032526//response to retinoic acid;GO:0071305//cellular response to vitamin D	--
ENSG00000104388	53.435	49.414	47.223	47.727	46.086	49.369	2626	2425	1841	1720	1829	1832	RAB2A	"RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9763]"	Environmental Information Processing	Signal transduction	ko04152//AMPK signaling pathway	K07877	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000104408	175.44	167.881	156.556	149.67	150.489	148.273	5527	5299	3543	3467	3945	3366	EIF3E	eukaryotic translation initiation factor 3 subunit E [Source:HGNC Symbol;Acc:HGNC:3277]	Human Diseases	Infectious disease: viral	ko05160//Hepatitis C	K03250	"GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0016605//PML body;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0070062//extracellular exosome;GO:0071540//eukaryotic translation initiation factor 3 complex, eIF3e"	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0047485//protein N-terminus binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation;GO:0045947//negative regulation of translational initiation;GO:1902416//positive regulation of mRNA binding"	--
ENSG00000104412	5.358	6.155	5.711	7.382	5.639	4.208	392	412	284	238	280	224	EMC2	ER membrane protein complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28963]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000104413	1.305	1.002	1.345	2.46	1.316	1.396	88	65	57	122	76	75	ESRP1	epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0042669//regulation of inner ear auditory receptor cell fate specification;GO:0043484//regulation of RNA splicing	--
ENSG00000104415	0.065	0.037	0.05	0.038	0.055	0	7	4	4	3	5	0	CCN4	cellular communication network factor 4 [Source:HGNC Symbol;Acc:HGNC:12769]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K22471	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0001649//osteoblast differentiation;GO:0001817//regulation of cytokine production;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030316//osteoclast differentiation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0042593//glucose homeostasis;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0060348//bone development;GO:0060548//negative regulation of cell death;GO:0090303//positive regulation of wound healing	--
ENSG00000104419	6.101	7.765	3.67	4.083	6.135	3.573	365	433	151	182	277	137	NDRG1	N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031267//small GTPase binding;GO:0043015//gamma-tubulin binding;GO:0045296//cadherin binding	"GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0010038//response to metal ion;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032287//peripheral nervous system myelin maintenance;GO:0042127//regulation of cell population proliferation;GO:0045576//mast cell activation;GO:0071456//cellular response to hypoxia"	--
ENSG00000104427	5.174	2.976	2.327	2.576	2.534	3.62	283	194	118	112	147	171	ZC2HC1A	zinc finger C2HC-type containing 1A [Source:HGNC Symbol;Acc:HGNC:24277]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000104432	0.102	0	0.062	0.069	0	0.105	4	0	1	2	0	3	IL7	interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05431;K05431;K05431;K05431;K05431	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005139//interleukin-7 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0002360//T cell lineage commitment;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0032722//positive regulation of chemokine production;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0045453//bone resorption;GO:0045579//positive regulation of B cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0046622//positive regulation of organ growth;GO:0048873//homeostasis of number of cells within a tissue;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000104435	0	0	0	0	0	0	0	0	0	0	0	0	STMN2	stathmin 2 [Source:HGNC Symbol;Acc:HGNC:10577]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0048306//calcium-dependent protein binding	GO:0007019//microtubule depolymerization;GO:0007026//negative regulation of microtubule depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031115//negative regulation of microtubule polymerization;GO:0031117//positive regulation of microtubule depolymerization;GO:0031175//neuron projection development;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000104442	12.087	11.999	12.651	9.778	10.304	12.305	751	748	531	440	530	546	ARMC1	armadillo repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:17684]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0048312//intracellular distribution of mitochondria	--
ENSG00000104447	2.513	1.264	1.561	1.649	1.503	1.886	296	187	163	140	160	159	TRPS1	transcriptional repressor GATA binding 1 [Source:HGNC Symbol;Acc:HGNC:12340]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032330//regulation of chondrocyte differentiation"	zf-GATA
ENSG00000104450	2.412	1.787	1.401	1.183	0.803	1.201	159	131	70	59	52	67	SPAG1	sperm associated antigen 1 [Source:HGNC Symbol;Acc:HGNC:11212]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101031//chaperone complex;GO:0120293//dynein axonemal particle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0007338//single fertilization;GO:0050821//protein stabilization;GO:0070286//axonemal dynein complex assembly	--
ENSG00000104472	8.126	7.275	8.275	8.127	10.264	8.542	309	297	211	235	287	258	CHRAC1	chromatin accessibility complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:13544]	-	-	-	-	GO:0005634//nucleus;GO:0005721//pericentric heterochromatin;GO:0008622//epsilon DNA polymerase complex;GO:0008623//CHRAC	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046982//protein heterodimerization activity	GO:0006275//regulation of DNA replication;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0042766//nucleosome mobilization;GO:0071897//DNA biosynthetic process	--
ENSG00000104490	4.691	3.909	3.981	2.884	3.891	3.993	295	250	170	154	237	183	NCALD	neurocalcin delta [Source:HGNC Symbol;Acc:HGNC:7655]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K19695	GO:0005829//cytosol;GO:0030130//clathrin coat of trans-Golgi network vesicle	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0030276//clathrin binding;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding	GO:0003073//regulation of systemic arterial blood pressure;GO:0016192//vesicle-mediated transport;GO:0019722//calcium-mediated signaling	--
ENSG00000104497	5.078	3.625	4.284	3.656	2.726	4.855	237	153	108	135	129	135	SNX16	sorting nexin 16 [Source:HGNC Symbol;Acc:HGNC:14980]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031313//extrinsic component of endosome membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0006622//protein targeting to lysosome;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0045022//early endosome to late endosome transport	--
ENSG00000104499	0	0	0	0	0	0	0	0	0	0	0	0	GML	glycosylphosphatidylinositol anchored molecule like [Source:HGNC Symbol;Acc:HGNC:4375]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane	-	"GO:0006915//apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0008285//negative regulation of cell population proliferation"	--
ENSG00000104517	22.95	22.627	21.022	9.806	21	11.928	3336	2965	1930	1334	1821	1507	UBR5	ubiquitin protein ligase E3 component n-recognin 5 [Source:HGNC Symbol;Acc:HGNC:16806]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10593	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010628//positive regulation of gene expression;GO:0016567//protein ubiquitination;GO:0042307//positive regulation of protein import into nucleus;GO:0050847//progesterone receptor signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:2000779//regulation of double-strand break repair;GO:2000780//negative regulation of double-strand break repair	--
ENSG00000104518	12.48	14.547	13.689	14.697	13.319	12.029	446	430	347	370	378	310	GSDMD	gasdermin D [Source:HGNC Symbol;Acc:HGNC:25697]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Immune system	ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko04621//NOD-like receptor signaling pathway	K20917;K20917;K20917	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035580//specific granule lumen;GO:0061702//inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	"GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0070300//phosphatidic acid binding;GO:1901612//cardiolipin binding"	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0012501//programmed cell death;GO:0031668//cellular response to extracellular stimulus;GO:0032731//positive regulation of interleukin-1 beta production;GO:0035915//pore formation in membrane of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0046931//pore complex assembly;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051260//protein homooligomerization;GO:0070269//pyroptosis	--
ENSG00000104522	23.999	23.753	23.535	26.493	24.448	18.376	606	638	462	534	548	373	GFUS	GDP-L-fucose synthase [Source:HGNC Symbol;Acc:HGNC:12390]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K02377;K02377;K02377	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016853//isomerase activity;GO:0042356//GDP-4-dehydro-D-rhamnose reductase activity;GO:0042802//identical protein binding;GO:0047918//GDP-mannose 3,5-epimerase activity;GO:0050577//GDP-L-fucose synthase activity"	GO:0007159//leukocyte cell-cell adhesion;GO:0008152//metabolic process;GO:0009226//nucleotide-sugar biosynthetic process;GO:0010595//positive regulation of endothelial cell migration;GO:0019673//GDP-mannose metabolic process;GO:0022900//electron transport chain;GO:0042351//'de novo' GDP-L-fucose biosynthetic process;GO:1904906//positive regulation of endothelial cell-matrix adhesion via fibronectin	--
ENSG00000104524	3.783	3.923	5	4.326	3.955	2.629	211	208	189	178	169	108	PYCR3	pyrroline-5-carboxylate reductase 3 [Source:HGNC Symbol;Acc:HGNC:25846]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism	K00286;K00286;K00286	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0004735//pyrroline-5-carboxylate reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006561//proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0055129//L-proline biosynthetic process	--
ENSG00000104529	185.061	193.241	185.763	200.471	191.59	188.67	4359	4543	3293	3545	3854	3230	EEF1D	eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0110165//cellular anatomical entity	"GO:0003677//DNA binding;GO:0003746//translation elongation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0031072//heat shock protein binding;GO:0045296//cadherin binding;GO:0140297//DNA-binding transcription factor binding"	GO:0006412//translation;GO:0006414//translational elongation;GO:0009299//mRNA transcription;GO:0010941//regulation of cell death;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050790//regulation of catalytic activity;GO:0071479//cellular response to ionizing radiation	--
ENSG00000104537	0	0	0	0	0	0	0	0	0	0	0	0	ANXA13	annexin A13 [Source:HGNC Symbol;Acc:HGNC:536]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0070382//exocytic vesicle	GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:1901611//phosphatidylglycerol binding	GO:0030154//cell differentiation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0042998//positive regulation of Golgi to plasma membrane protein transport	--
ENSG00000104549	50.453	49.091	51.532	54.543	48.781	58.446	3074	3003	2266	2470	2532	2594	SQLE	squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K00511;K00511	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004497//monooxygenase activity;GO:0004506//squalene monooxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding	GO:0006629//lipid metabolic process;GO:0006725//cellular aromatic compound metabolic process;GO:0008203//cholesterol metabolic process;GO:0010033//response to organic substance;GO:0016126//sterol biosynthetic process;GO:0042127//regulation of cell population proliferation;GO:0140042//lipid droplet formation	--
ENSG00000104611	2.762	3.1	4.248	5.516	4.638	3.921	135	138	67	166	191	113	SH2D4A	SH2 domain containing 4A [Source:HGNC Symbol;Acc:HGNC:26102]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019902//phosphatase binding	-	--
ENSG00000104613	13.852	11.382	11.7	10.005	10.157	12.004	572	558	425	369	448	420	INTS10	integrator complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:25548]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing	--
ENSG00000104626	3.549	3.078	2.986	2.738	2.155	2.069	277	247	154	165	146	119	ERI1	exoribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:23994]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0071204//histone pre-mRNA 3'end processing complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0019843//rRNA binding;GO:0043022//ribosome binding;GO:0046872//metal ion binding;GO:0071207//histone pre-mRNA stem-loop binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0031047//gene silencing by RNA;GO:0031125//rRNA 3'-end processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000104635	13.23	13.407	13.533	12.437	12.722	14.167	1238	1268	936	891	1003	997	SLC39A14	solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Cell growth and death	ko05010//Alzheimer disease;ko05012//Parkinson disease;ko04216//Ferroptosis	K14720;K14720;K14720	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane	GO:0005381//iron ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0015086//cadmium ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015296//anion:cation symporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0002062//chondrocyte differentiation;GO:0006094//gluconeogenesis;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0008286//insulin receptor signaling pathway;GO:0010817//regulation of hormone levels;GO:0015698//inorganic anion transport;GO:0030001//metal ion transport;GO:0032869//cellular response to insulin stimulus;GO:0033212//iron import into cell;GO:0034755//iron ion transmembrane transport;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0055071//manganese ion homeostasis;GO:0055085//transmembrane transport;GO:0070574//cadmium ion transmembrane transport;GO:0071333//cellular response to glucose stimulus;GO:0071421//manganese ion transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071578//zinc ion import across plasma membrane;GO:0098662//inorganic cation transmembrane transport;GO:0098739//import across plasma membrane	--
ENSG00000104643	5.274	4.207	4.305	4.097	4.842	5.057	698	562	434	390	511	483	MTMR9	myotubularin related protein 9 [Source:HGNC Symbol;Acc:HGNC:14596]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030234//enzyme regulator activity	GO:0006897//endocytosis;GO:0010507//negative regulation of autophagy;GO:0010922//positive regulation of phosphatase activity;GO:0046856//phosphatidylinositol dephosphorylation;GO:0050821//protein stabilization;GO:0060304//regulation of phosphatidylinositol dephosphorylation	--
ENSG00000104660	98.432	88.16	72.831	79.381	94.539	62.614	4652	4824	2672	3113	3732	2320	LEPROTL1	leptin receptor overlapping transcript like 1 [Source:HGNC Symbol;Acc:HGNC:6555]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0060400//negative regulation of growth hormone receptor signaling pathway	--
ENSG00000104671	25.998	29.549	27.003	26.553	22.37	27.397	568	649	436	430	412	435	DCTN6	dynactin subunit 6 [Source:HGNC Symbol;Acc:HGNC:16964]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10428;K10428;K10428;K10428;K10428	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex"	GO:0070840//dynein complex binding	GO:0007052//mitotic spindle organization	--
ENSG00000104679	24.145	27.67	25.468	28.846	28.254	29.36	707	825	571	697	728	627	R3HCC1	R3H domain and coiled-coil containing 1 [Source:HGNC Symbol;Acc:HGNC:27329]	-	-	-	-	-	GO:0003676//nucleic acid binding	-	--
ENSG00000104687	21.721	24.308	23.521	17.333	20.023	19.222	1347	1492	1054	808	1014	809	GSR	glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623]	Metabolism;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Cardiovascular disease;Endocrine system;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04918//Thyroid hormone synthesis;ko00480//Glutathione metabolism	K00383;K00383;K00383;K00383	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004362//glutathione-disulfide reductase (NADPH) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	GO:0006749//glutathione metabolic process;GO:0022900//electron transport chain;GO:0034599//cellular response to oxidative stress;GO:0045454//cell redox homeostasis;GO:0098869//cellular oxidant detoxification	--
ENSG00000104689	0.395	0.297	0.388	0.097	0.139	0.572	8	12	16	4	5	14	TNFRSF10A	TNF receptor superfamily member 10a [Source:HGNC Symbol;Acc:HGNC:11904]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Immune system;Infectious disease: viral;Cell growth and death;Cell growth and death;Signaling molecules and interaction;Cell growth and death	ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04217//Necroptosis;ko04210//Apoptosis;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04115//p53 signaling pathway	K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0110165//cellular anatomical entity	GO:0002020//protease binding;GO:0005035//death receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0045569//TRAIL binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0097191//extrinsic apoptotic signaling pathway	--
ENSG00000104691	3.93	6.451	4.904	6.688	4.336	4.215	119	186	105	128	111	94	UBXN8	UBX domain protein 8 [Source:HGNC Symbol;Acc:HGNC:30307]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K24351	GO:0000151//ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003676//nucleic acid binding;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0043130//ubiquitin binding	"GO:0007338//single fertilization;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0044260//cellular macromolecule metabolic process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000104695	35.254	34.458	36.396	32.911	32.315	38.101	1423	1398	1085	984	1102	1119	PPP2CB	protein phosphatase 2 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9300]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Transport and catabolism;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation;Signal transduction;Nervous system;Transport and catabolism;Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04140//Autophagy - animal;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway;ko04350//TGF-beta signaling pathway;ko04730//Long-term depression;ko04136//Autophagy - other;ko04013//MAPK signaling pathway - fly;ko04391//Hippo signaling pathway - fly	K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382	"GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton"	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0008637//apoptotic mitochondrial changes;GO:0010288//response to lead ion;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034976//response to endoplasmic reticulum stress;GO:0035970//peptidyl-threonine dephosphorylation;GO:0042542//response to hydrogen peroxide;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:0046677//response to antibiotic;GO:0070262//peptidyl-serine dephosphorylation;GO:1904528//positive regulation of microtubule binding	--
ENSG00000104714	4.653	4.052	3.621	3.228	4.702	3.712	183	155	107	95	151	107	ERICH1	glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:27234]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000104722	0.31	0.117	0.131	0.026	0.114	0.042	21	7	5	1	5	2	NEFM	neurofilament medium chain [Source:HGNC Symbol;Acc:HGNC:7734]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K04573;K04573	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005883//neurofilament;GO:0030424//axon;GO:0042995//cell projection;GO:0045111//intermediate filament cytoskeleton;GO:0097418//neurofibrillary tangle	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0033693//neurofilament bundle assembly	--
ENSG00000104723	65.449	65.248	70.268	62.552	60.751	69.726	2332	2334	1890	1608	1834	1766	TUSC3	tumor suppressor candidate 3 [Source:HGNC Symbol;Acc:HGNC:30242]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K12669;K12669;K12669;K12669	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015095//magnesium ion transmembrane transporter activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0015693//magnesium ion transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0050890//cognition;GO:0055085//transmembrane transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000104728	8.526	7.808	8.933	7.151	8.596	8.74	962.1	891.4	754.21	593.67	794.51	704.5	ARHGEF10	Rho guanine nucleotide exchange factor 10 [Source:HGNC Symbol;Acc:HGNC:14103]	-	-	-	-	GO:0005813//centrosome;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0022011//myelination in peripheral nervous system;GO:0030036//actin cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051298//centrosome duplication;GO:0051496//positive regulation of stress fiber assembly;GO:0090307//mitotic spindle assembly;GO:0090630//activation of GTPase activity	--
ENSG00000104731	6.952	8.122	8.18	8.143	8.714	6.415	335	369	281	283	348	228	KLHDC4	kelch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25272]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000104738	22.635	16.432	17.831	16.061	15.465	18.485	730	844	530	458	555	436	MCM4	minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02212;K02212	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0042555//MCM complex;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0007049//cell cycle;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:1902975//mitotic DNA replication initiation	--
ENSG00000104755	0	0	0	0	0	0	0	0	0	0	0	0	ADAM2	ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0008542//visual learning;GO:0010628//positive regulation of gene expression;GO:0030534//adult behavior	--
ENSG00000104756	4.246	3.826	3.897	3.286	3.026	3.617	289	261	183	170	176	181	KCTD9	potassium channel tetramerization domain containing 9 [Source:HGNC Symbol;Acc:HGNC:22401]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0097602//cullin family protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0051260//protein homooligomerization	--
ENSG00000104760	0	0	0	0	0	0	0	0	0	0	0	0	FGL1	fibrinogen like 1 [Source:HGNC Symbol;Acc:HGNC:3695]	-	-	-	-	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0050776//regulation of immune response;GO:0050868//negative regulation of T cell activation;GO:0072574//hepatocyte proliferation	--
ENSG00000104763	309.202	297.683	307.946	366.599	334.454	385.802	12553	11891	9115	10755	11322	11290	ASAH1	N-acylsphingosine amidohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:735]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K12348;K12348;K12348;K12348	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	"GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016922//nuclear receptor binding;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0017064//fatty acid amide hydrolase activity;GO:0102121//ceramidase activity"	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030216//keratinocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0046514//ceramide catabolic process;GO:0050810//regulation of steroid biosynthetic process;GO:0062098//regulation of programmed necrotic cell death;GO:0071356//cellular response to tumor necrosis factor;GO:1903507//negative regulation of nucleic acid-templated transcription"	--
ENSG00000104765	50.81	52.511	43.002	36.287	42.039	42.922	3013.43	2894.09	1824	1645	1938	1751.12	BNIP3L	BCL2 interacting protein 3 like [Source:HGNC Symbol;Acc:HGNC:1085]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K15465	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031224//intrinsic component of membrane	GO:0005515//protein binding;GO:0005521//lamin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006915//apoptotic process;GO:0016239//positive regulation of macroautophagy;GO:0035694//mitochondrial protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043067//regulation of programmed cell death;GO:0051607//defense response to virus;GO:0060548//negative regulation of cell death;GO:0071456//cellular response to hypoxia;GO:0097345//mitochondrial outer membrane permeabilization;GO:1903146//regulation of autophagy of mitochondrion;GO:1903214//regulation of protein targeting to mitochondrion	--
ENSG00000104774	44.14	48.522	48.834	53.05	49.741	49.858	2916	3222	2382.71	2595.99	2776.21	2372	MAN2B1	mannosidase alpha class 2B member 1 [Source:HGNC Symbol;Acc:HGNC:6826]	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K12311;K12311	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0006464//cellular protein modification process;GO:0006517//protein deglycosylation;GO:0008152//metabolic process	--
ENSG00000104783	0.296	0.114	0.292	0.265	0.233	0.332	12	4	6	4	8	5	KCNN4	potassium calcium-activated channel subfamily N member 4 [Source:HGNC Symbol;Acc:HGNC:6293]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Endocrine system;Endocrine system	ko04974//Protein digestion and absorption;ko04970//Salivary secretion;ko04911//Insulin secretion;ko04929//GnRH secretion	K04945;K04945;K04945;K04945	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity;GO:0019903//protein phosphatase binding;GO:0022894//Intermediate conductance calcium-activated potassium channel activity	GO:0002376//immune system process;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006816//calcium ion transport;GO:0006884//cell volume homeostasis;GO:0006952//defense response;GO:0030322//stabilization of membrane potential;GO:0045332//phospholipid translocation;GO:0046541//saliva secretion;GO:0050714//positive regulation of protein secretion;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0071805//potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport	--
ENSG00000104804	0	0.082	0	0	0	0.038	0	3	0	0	0	1	TULP2	TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005929//cilium	GO:0044877//protein-containing complex binding	GO:0007601//visual perception;GO:0061512//protein localization to cilium	Tub
ENSG00000104805	165.164	183.263	180.039	202.549	201.238	173.962	7377	7991	5964	6883	7423	5692	NUCB1	nucleobindin 1 [Source:HGNC Symbol;Acc:HGNC:8043]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001965//G-protein alpha-subunit binding;GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000104808	0	0.045	0	0	0.08	0	0	1	0	0	1	0	DHDH	dihydrodiol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:17887]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00040//Pentose and glucuronate interconversions	K00078;K00078;K00078	-	"GO:0000166//nucleotide binding;GO:0016491//oxidoreductase activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047837//D-xylose 1-dehydrogenase (NADP+) activity"	GO:0042843//D-xylose catabolic process	--
ENSG00000104812	21.803	22.914	24.081	27.401	30.891	25.732	1614	1705	1316	1477	1931	1386	GYS1	glycogen synthase 1 [Source:HGNC Symbol;Acc:HGNC:4706]	Metabolism;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Cardiovascular disease;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko05415//Diabetic cardiomyopathy;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00500//Starch and sucrose metabolism	K00693;K00693;K00693;K00693;K00693;K00693;K00693;K00693	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016234//inclusion body	"GO:0003824//catalytic activity;GO:0004373//glycogen (starch) synthase activity;GO:0005515//protein binding;GO:0005536//glucose binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019901//protein kinase binding;GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate"	GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0007507//heart development;GO:0008152//metabolic process	--
ENSG00000104814	2.246	2.351	1.607	2.027	2.137	2.467	86	94	46	62	75	70	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6863]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04408	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0046777//protein autophosphorylation;GO:1904628//cellular response to phorbol 13-acetate 12-myristate	--
ENSG00000104818	0	0.148	0	0	0	0	0	2.39	0	0	0	0	CGB2	chorionic gonadotropin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:16722]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000104823	55.607	58.525	69.08	76.269	65.729	75.385	1347	1455	1260	1313	1352	1324	ECH1	enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K12663	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0051750//delta3,5-delta2,4-dienoyl-CoA isomerase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000104824	70.219	78.084	74.581	69.392	70.802	68.667	2467	2767	1928	1790	2093	1752	HNRNPL	heterogeneous nuclear ribonucleoprotein L [Source:HGNC Symbol;Acc:HGNC:5045]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0035770//ribonucleoprotein granule;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0000976//transcription cis-regulatory region binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0097157//pre-mRNA intronic binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0043484//regulation of RNA splicing;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000104825	8.899	8.807	8.061	9.378	7.714	10.374	278	297	204.53	228	214	265	NFKBIB	NFKB inhibitor beta [Source:HGNC Symbol;Acc:HGNC:7798]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Immune system;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Nervous system;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Immune system;Endocrine system;Immune system	ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04722//Neurotrophin signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04622//RIG-I-like receptor signaling pathway;ko04920//Adipocytokine signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581;K02581	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071222//cellular response to lipopolysaccharide"	--
ENSG00000104826	0	0	0	0	0	0	0	0	0	0	0	0	LHB	luteinizing hormone subunit beta [Source:HGNC Symbol;Acc:HGNC:6584]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Endocrine system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04912//GnRH signaling pathway;ko04917//Prolactin signaling pathway;ko04929//GnRH secretion;ko04913//Ovarian steroidogenesis	K08521;K08521;K08521;K08521;K08521;K08521	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005796//Golgi lumen;GO:0061696//pituitary gonadotropin complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006701//progesterone biosynthetic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008584//male gonad development;GO:0009755//hormone-mediated signaling pathway	--
ENSG00000104827	0	0	0	0	0	0	0	0	0	0	0	0	CGB3	chorionic gonadotropin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1886]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0061696//pituitary gonadotropin complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0009755//hormone-mediated signaling pathway	--
ENSG00000104833	160.868	170.018	199.76	248.795	220.43	213.726	7134	7694	6308.61	8085	8279	6913	TUBB4A	tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0033269//internode region of axon;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0031115//negative regulation of microtubule polymerization	--
ENSG00000104835	4.686	4.788	6.508	6.985	5.784	6.061	187	184	188	203	195	176	SARS2	"seryl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17697]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01875	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004828//serine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006434//seryl-tRNA aminoacylation;GO:0070158//mitochondrial seryl-tRNA aminoacylation;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process	--
ENSG00000104848	0.023	0.035	0	0	0	0.016	2	3	0	0	0	1	KCNA7	potassium voltage-gated channel subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:6226]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000104852	64.458	63.92	71.525	80.098	70.069	76.687	2277	2279	1891	2157	2144	2027	SNRNP70	small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11093	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005685//U1 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0030619//U1 snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0043462//regulation of ATPase activity;GO:0043484//regulation of RNA splicing;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0061084//negative regulation of protein refolding;GO:1904715//negative regulation of chaperone-mediated autophagy"	--
ENSG00000104853	109.238	113.395	121.189	139.03	133.852	127.138	5595	5833	4543	5273	5755	4735	CLPTM1	CLPTM1 regulator of GABA type A receptor forward trafficking [Source:HGNC Symbol;Acc:HGNC:2087]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0033081//regulation of T cell differentiation in thymus	--
ENSG00000104856	2.01	2.216	2.267	1.818	2.426	1.858	94	105	78	63	96	63	RELB	"RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956]"	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Infectious disease: viral;Infectious disease: viral;Signal transduction;Development and regeneration;Immune system	ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04064//NF-kappa B signaling pathway;ko04380//Osteoclast differentiation;ko04625//C-type lectin receptor signaling pathway	K09253;K09253;K09253;K09253;K09253;K09253	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex;GO:0071159//NF-kappaB complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010628//positive regulation of gene expression;GO:0019882//antigen processing and presentation;GO:0030098//lymphocyte differentiation;GO:0032479//regulation of type I interferon production;GO:0032688//negative regulation of interferon-beta production;GO:0032922//circadian regulation of gene expression;GO:0034097//response to cytokine;GO:0038061//NIK/NF-kappaB signaling;GO:0042088//T-helper 1 type immune response;GO:0043011//myeloid dendritic cell differentiation;GO:0045063//T-helper 1 cell differentiation;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0071470//cellular response to osmotic stress"	RHD
ENSG00000104859	5.49	4.702	5.997	6.819	6.679	7.791	238	190	181	182	221	238	CLASRP	CLK4 associating serine/arginine rich protein [Source:HGNC Symbol;Acc:HGNC:17731]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000104863	2.324	1.093	1.565	1.684	0.972	0.977	27	17	18	19	12	11	LIN7B	"lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030165//PDZ domain binding;GO:0097016//L27 domain binding	GO:0006887//exocytosis;GO:0007269//neurotransmitter secretion;GO:0015031//protein transport;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000104866	11.635	10.738	13.975	13.521	12.261	13.561	621	629	529	612	633	594	PPP1R37	protein phosphatase 1 regulatory subunit 37 [Source:HGNC Symbol;Acc:HGNC:27607]	-	-	-	-	-	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity	--
ENSG00000104870	67.415	76.358	80.526	79.568	72.093	78.385	2069	2324	1763	1825	1855	1699	FCGRT	Fc fragment of IgG receptor and transporter [Source:HGNC Symbol;Acc:HGNC:3621]	-	-	-	-	GO:0005615//extracellular space;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019864//IgG binding;GO:0030881//beta-2-microglobulin binding	GO:0002416//IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	--
ENSG00000104872	30.982	27.335	29.769	35.029	30.931	26.02	708	650	532	621	638	445	PIH1D1	PIH1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26075]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0070761//pre-snoRNP complex;GO:0097255//R2TP complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex;GO:1990904//ribonucleoprotein complex	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042393//histone binding;GO:0051117//ATPase binding;GO:0051219//phosphoprotein binding	GO:0000492//box C/D snoRNP assembly;GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006338//chromatin remodeling;GO:0006364//rRNA processing;GO:0030855//epithelial cell differentiation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0048254//snoRNA localization;GO:0050821//protein stabilization;GO:0051569//regulation of histone H3-K4 methylation;GO:0071169//establishment of protein localization to chromatin;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090240//positive regulation of histone H4 acetylation;GO:1900110//negative regulation of histone H3-K9 dimethylation;GO:1900113//negative regulation of histone H3-K9 trimethylation;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1902661//positive regulation of glucose mediated signaling pathway;GO:1904263//positive regulation of TORC1 signaling;GO:1905669//TORC1 complex assembly;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:2000619//negative regulation of histone H4-K16 acetylation;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000104879	0.031	0.216	0.042	0	0.073	0	1	7	1	0	2	0	CKM	"creatine kinase, M-type [Source:HGNC Symbol;Acc:HGNC:1994]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00933;K00933	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004111//creatine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0016310//phosphorylation;GO:0046314//phosphocreatine biosynthetic process	--
ENSG00000104880	11.501	13.081	12.333	11.931	12.327	12.619	1290	1479	1016	996	1160	1016	ARHGEF18	Rho/Rac guanine nucleotide exchange factor 18 [Source:HGNC Symbol;Acc:HGNC:17090]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21066	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051497//negative regulation of stress fiber assembly;GO:0150105//protein localization to cell-cell junction	--
ENSG00000104881	7.323	5.584	8.792	8.354	7.156	6.529	219	258	220	210	233	178	PPP1R13L	protein phosphatase 1 regulatory subunit 13 like [Source:HGNC Symbol;Acc:HGNC:18838]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045171//intercellular bridge	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003215//cardiac right ventricle morphogenesis;GO:0003229//ventricular cardiac muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0009791//post-embryonic development;GO:0031076//embryonic camera-type eye development;GO:0035264//multicellular organism growth;GO:0042633//hair cycle;GO:0045597//positive regulation of cell differentiation;GO:0048871//multicellular organismal homeostasis;GO:0060048//cardiac muscle contraction"	--
ENSG00000104883	2.57	2.572	2.842	1.992	2.012	2.582	57	59	46	34	38	42	PEX11G	peroxisomal biogenesis factor 11 gamma [Source:HGNC Symbol;Acc:HGNC:20208]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13353	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0016559//peroxisome fission;GO:0044375//regulation of peroxisome size	--
ENSG00000104884	13.389	12.941	14.903	18.935	14.179	13.865	858.67	905	695	819	878	737	ERCC2	"ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434]"	Genetic Information Processing;Genetic Information Processing	Transcription;Replication and repair	ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K10844;K10844	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0070516//CAK-ERCC2 complex;GO:0071817//MMXD complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003684//damaged DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0030674//protein-macromolecule adaptor activity;GO:0043139//5'-3' DNA helicase activity;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000717//nucleotide-excision repair, DNA duplex unwinding;GO:0001701//in utero embryonic development;GO:0006139//nucleobase-containing compound metabolic process;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007059//chromosome segregation;GO:0007568//aging;GO:0008283//cell population proliferation;GO:0009411//response to UV;GO:0009650//UV protection;GO:0009791//post-embryonic development;GO:0021510//spinal cord development;GO:0022405//hair cycle process;GO:0030198//extracellular matrix organization;GO:0030282//bone mineralization;GO:0032289//central nervous system myelin formation;GO:0032508//DNA duplex unwinding;GO:0033683//nucleotide-excision repair, DNA incision;GO:0035264//multicellular organism growth;GO:0035315//hair cell differentiation;GO:0040016//embryonic cleavage;GO:0042274//ribosomal small subunit biogenesis;GO:0043249//erythrocyte maturation;GO:0043388//positive regulation of DNA binding;GO:0043588//skin development;GO:0045951//positive regulation of mitotic recombination;GO:0048820//hair follicle maturation;GO:0060218//hematopoietic stem cell differentiation;GO:1901990//regulation of mitotic cell cycle phase transition"	--
ENSG00000104885	6.363	6.488	7.914	7.768	8.624	8.689	921.97	929.7	835.13	858.16	974.07	796.97	DOT1L	DOT1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:24948]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05202//Transcriptional misregulation in cancer;ko00310//Lysine degradation	K11427;K11427;K11427	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0031151//histone methyltransferase activity (H3-K79 specific);GO:0042054//histone methyltransferase activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0008284//positive regulation of cell population proliferation;GO:0010467//gene expression;GO:0031507//heterochromatin assembly;GO:0032200//telomere organization;GO:0032259//methylation;GO:0034729//histone H3-K79 methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0051726//regulation of cell cycle;GO:2000677//regulation of transcription regulatory region DNA binding"	--
ENSG00000104886	18.053	18.623	18.042	23.059	21.027	20.163	456.03	475.3	338.87	433.84	446.93	374.03	PLEKHJ1	pleckstrin homology domain containing J1 [Source:HGNC Symbol;Acc:HGNC:18211]	-	-	-	-	GO:0005769//early endosome;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0055037//recycling endosome	GO:0005515//protein binding	"GO:0001881//receptor recycling;GO:0007032//endosome organization;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000104888	0.114	0.043	0.175	0.044	0.019	0.18	7	2	6	2	1	8	SLC17A7	solute carrier family 17 member 7 [Source:HGNC Symbol;Acc:HGNC:16704]	Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Nervous system;Nervous system;Nervous system;Substance dependence	ko04723//Retrograde endocannabinoid signaling;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle;ko05033//Nicotine addiction	K12302;K12302;K12302;K12302	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043229//intracellular organelle;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0060076//excitatory synapse;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005436//sodium:phosphate symporter activity;GO:0015293//symporter activity;GO:0015319//sodium:inorganic phosphate symporter activity;GO:0022857//transmembrane transporter activity	"GO:0003407//neural retina development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0006820//anion transport;GO:0006836//neurotransmitter transport;GO:0007420//brain development;GO:0015813//L-glutamate transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035725//sodium ion transmembrane transport;GO:0050803//regulation of synapse structure or activity;GO:0055085//transmembrane transport;GO:0098700//neurotransmitter loading into synaptic vesicle;GO:1900242//regulation of synaptic vesicle endocytosis"	--
ENSG00000104889	11.934	13.557	14.175	9.715	8.824	8.14	286.79	329	250	173	180	143	RNASEH2A	ribonuclease H2 subunit A [Source:HGNC Symbol;Acc:HGNC:18518]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K10743	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032299//ribonuclease H2 complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006260//DNA replication;GO:0006298//mismatch repair;GO:0006401//RNA catabolic process;GO:0016070//RNA metabolic process;GO:0043137//DNA replication, removal of RNA primer;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000104892	3.986	3.826	2.674	3.693	3.365	3.96	147.33	142	73	101	105	103	KLC3	kinesin light chain 3 [Source:HGNC Symbol;Acc:HGNC:20717]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection	K10407;K10407;K10407;K10407;K10407;K10407;K10407	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0031514//motile cilium;GO:0035253//ciliary rootlet;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008088//axo-dendritic transport;GO:0120317//sperm mitochondrial sheath assembly	--
ENSG00000104894	0.121	0	0.163	0.156	0.072	0.083	4	0	4	4	2	2	CD37	CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06475	GO:0001772//immunological synapse;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000104897	20.368	21.509	22.095	27.176	25.871	26.889	684	726	548	676	734	657	SF3A2	splicing factor 3a subunit 2 [Source:HGNC Symbol;Acc:HGNC:10766]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12826	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010976//positive regulation of neuron projection development;GO:1903241//U2-type prespliceosome assembly"	--
ENSG00000104899	0.346	0.292	0.397	0.54	0.536	0.366	13	11	11	15	17	10	AMH	anti-Mullerian hormone [Source:HGNC Symbol;Acc:HGNC:464]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04024//cAMP signaling pathway;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K04665;K04665;K04665;K04665	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001541//ovarian follicle development;GO:0001546//preantral ovarian follicle growth;GO:0001655//urogenital system development;GO:0001880//Mullerian duct regression;GO:0007267//cell-cell signaling;GO:0007506//gonadal mesoderm development;GO:0007530//sex determination;GO:0007548//sex differentiation;GO:0007568//aging;GO:0008406//gonad development;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0033327//Leydig cell differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:2000355//negative regulation of ovarian follicle development	--
ENSG00000104901	0.126	0	0.522	0.208	0	0.086	2	0	4	3	0	1	DKKL1	dickkopf like acrosomal protein 1 [Source:HGNC Symbol;Acc:HGNC:16528]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle	GO:0039706//co-receptor binding;GO:0048019//receptor antagonist activity	GO:0007341//penetration of zona pellucida;GO:0009653//anatomical structure morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0045600//positive regulation of fat cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000225//negative regulation of testosterone biosynthetic process;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000104903	0.684	0.162	0.088	0	0.039	0.121	21	5	2	0	1	2	LYL1	LYL1 basic helix-loop-helix family member [Source:HGNC Symbol;Acc:HGNC:6734]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15604	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0001955//blood vessel maturation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030183//B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060216//definitive hemopoiesis"	bHLH
ENSG00000104904	168.743	161.219	168.734	169.608	163.117	184.924	3861	3692	2868	2855	3178	3094	OAZ1	ornithine decarboxylase antizyme 1 [Source:HGNC Symbol;Acc:HGNC:8095]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008073//ornithine decarboxylase inhibitor activity	GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0043086//negative regulation of catalytic activity;GO:0045732//positive regulation of protein catabolic process;GO:0050790//regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport;GO:1902268//negative regulation of polyamine transmembrane transport	--
ENSG00000104907	8.494	8.092	8.072	8.336	9.965	8.158	354	327	264	260	361	262	TRMT1	tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25980]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0002940//tRNA N2-guanine methylation;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000104915	21.216	21.541	25.428	22.41	21.707	24.107	552	550	433	427	472	447	STX10	syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23937	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0031982//vesicle;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032880//regulation of protein localization;GO:0042147//retrograde transport, endosome to Golgi;GO:0048193//Golgi vesicle transport;GO:0048278//vesicle docking;GO:0061025//membrane fusion"	--
ENSG00000104918	0	0	0	0	0	0	0	0	0	0	0	0	RETN	resistin [Source:HGNC Symbol;Acc:HGNC:20389]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007568//aging;GO:0008150//biological_process;GO:0009612//response to mechanical stimulus;GO:0032868//response to insulin;GO:0045444//fat cell differentiation;GO:0050806//positive regulation of synaptic transmission;GO:2000252//negative regulation of feeding behavior;GO:2000872//positive regulation of progesterone secretion	--
ENSG00000104921	0	0	0	0	0	0	0	0	0	0	0	0	FCER2	Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05169//Epstein-Barr virus infection;ko04640//Hematopoietic cell lineage	K06468;K06468	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019863//IgE binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051712//positive regulation of killing of cells of other organism;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process	--
ENSG00000104936	10.685	9.401	8.872	10.04	9.069	10.671	552	527	362	355	415	389	DMPK	DM1 protein kinase [Source:HGNC Symbol;Acc:HGNC:2933]	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031307//integral component of mitochondrial outer membrane;GO:0031965//nuclear membrane;GO:0031966//mitochondrial membrane;GO:0033017//sarcoplasmic reticulum membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017020//myosin phosphatase regulator activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0002028//regulation of sodium ion transport;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006998//nuclear envelope organization;GO:0008016//regulation of heart contraction;GO:0010657//muscle cell apoptotic process;GO:0010830//regulation of myotube differentiation;GO:0014722//regulation of skeletal muscle contraction by calcium ion signaling;GO:0014853//regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051823//regulation of synapse structural plasticity	--
ENSG00000104938	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4M	C-type lectin domain family 4 member M [Source:HGNC Symbol;Acc:HGNC:13523]	Human Diseases;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Immune system	ko05152//Tuberculosis;ko04145//Phagosome;ko05162//Measles;ko04625//C-type lectin receptor signaling pathway	K06563;K06563;K06563;K06563	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043657//host cell	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0030369//ICAM-3 receptor activity;GO:0038023//signaling receptor activity;GO:0042605//peptide antigen binding;GO:0046790//virion binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006897//endocytosis;GO:0007159//leukocyte cell-cell adhesion;GO:0009988//cell-cell recognition;GO:0019062//virion attachment to host cell;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019079//viral genome replication;GO:0019882//antigen processing and presentation;GO:0035556//intracellular signal transduction;GO:0045087//innate immune response;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0046968//peptide antigen transport;GO:0075733//intracellular transport of virus	--
ENSG00000104941	0	0	0	0	0	0	0	0	0	0	0	0	RSPH6A	radial spoke head 6 homolog A [Source:HGNC Symbol;Acc:HGNC:14241]	-	-	-	-	GO:0001534//radial spoke;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0035082//axoneme assembly;GO:0044458//motile cilium assembly;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility;GO:1905199//manchette disassembly	--
ENSG00000104946	16.028	17.515	17.748	17.834	21.056	18.554	667	732	568	571	759	573	TBC1D17	TBC1 domain family member 17 [Source:HGNC Symbol;Acc:HGNC:25699]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K19945	GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0006914//autophagy;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0090630//activation of GTPase activity"	--
ENSG00000104951	0.027	0.027	0.109	0.324	0.032	0	1	1	3	3	1	0	IL4I1	interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00380//Tryptophan metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko00350//Tyrosine metabolism;ko00360//Phenylalanine metabolism;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K03334;K03334;K03334;K03334;K03334;K03334;K03334;K03334	GO:0001669//acrosomal vesicle;GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle;GO:0097225//sperm midpiece	GO:0001716//L-amino-acid oxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046592//polyamine oxidase activity;GO:0106329//L-phenylalaine oxidase activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002819//regulation of adaptive immune response;GO:0002841//negative regulation of T cell mediated immune response to tumor cell;GO:0006559//L-phenylalanine catabolic process;GO:0006569//tryptophan catabolic process;GO:0006572//tyrosine catabolic process;GO:0009063//cellular amino acid catabolic process;GO:0019440//tryptophan catabolic process to indole-3-acetate;GO:0042130//negative regulation of T cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050868//negative regulation of T cell activation	--
ENSG00000104953	0.026	0.102	0.231	0	0.224	0	1	4	7	0	5	0	TLE6	"TLE family member 6, subcortical maternal complex member [Source:HGNC Symbol;Acc:HGNC:30788]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0032991//protein-containing complex;GO:0106333//subcortical maternal complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007015//actin filament organization;GO:0040019//positive regulation of embryonic development;GO:0051293//establishment of spindle localization;GO:0051302//regulation of cell division;GO:0051643//endoplasmic reticulum localization;GO:0051646//mitochondrion localization;GO:0060136//embryonic process involved in female pregnancy;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000104957	10.028	10.344	9.909	10.426	10.96	12.564	335	356	241	266	306	319	YJU2B	YJU2 splicing factor homolog B [Source:HGNC Symbol;Acc:HGNC:28118]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005684//U2-type spliceosomal complex;GO:0071014//post-mRNA release spliceosomal complex	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0009615//response to virus"	--
ENSG00000104960	119.795	115.256	128.611	133.538	123.665	137.049	3955	3818	3136	3234	3443	3261	PTOV1	PTOV1 extended AT-hook containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:9632]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	-	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000104964	102.817	100.291	115.117	118.219	105.779	110.687	3805	3748	3173	3266	3322	3008	TLE5	"TLE family member 5, transcriptional modulator [Source:HGNC Symbol;Acc:HGNC:307]"	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0009887//animal organ morphogenesis;GO:0010629//negative regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0032091//negative regulation of protein binding;GO:0040008//regulation of growth;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060761//negative regulation of response to cytokine stimulus;GO:0070555//response to interleukin-1;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000210//positive regulation of anoikis"	--
ENSG00000104967	0.053	0.041	0.024	0.008	0.035	0.016	9	7	3	1	5	2	NOVA2	NOVA alternative splicing regulator 2 [Source:HGNC Symbol;Acc:HGNC:7887]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:1990825//sequence-specific mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0021954//central nervous system neuron development;GO:0030182//neuron differentiation;GO:0051252//regulation of RNA metabolic process;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1902667//regulation of axon guidance"	--
ENSG00000104969	66.779	68.061	70.756	85.404	78.32	81.852	2906	2957	2186	2815	2864	2664	SGTA	small glutamine rich tetratricopeptide repeat co-chaperone alpha [Source:HGNC Symbol;Acc:HGNC:10819]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0072380//TRC complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0060090//molecular adaptor activity;GO:1904288//BAT3 complex binding	GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1903070//negative regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000104972	0	0	0	0	0	0	0	0	0	0	0	0	LILRB1	leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	-	-	--
ENSG00000104973	21.446	22.079	22.21	22.055	23.613	23.651	1348	1388	1047	994	1222	1057	MED25	mediator complex subunit 25 [Source:HGNC Symbol;Acc:HGNC:28845]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0001223//transcription coactivator binding;GO:0005515//protein binding;GO:0042974//retinoic acid receptor binding;GO:0046965//retinoid X receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0035563//positive regulation of chromatin binding;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048147//negative regulation of fibroblast proliferation;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:2001178//positive regulation of mediator complex assembly	--
ENSG00000104974	0	0	0	0	0.025	0	0	0	0	0	1	0	LILRA1	leukocyte immunoglobulin like receptor A1 [Source:HGNC Symbol;Acc:HGNC:6602]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003823//antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0032396//inhibitory MHC class I receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000104976	9.383	11.441	9.467	11.015	10.738	11.498	291	356	220	254	285	263	SNAPC2	small nuclear RNA activating complex polypeptide 2 [Source:HGNC Symbol;Acc:HGNC:11135]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0006366//transcription by RNA polymerase II;GO:0006383//transcription by RNA polymerase III;GO:0009301//snRNA transcription	--
ENSG00000104979	45.437	46.411	45.166	49.47	41.733	44.395	776	813	576	603	598	601	C19orf53	chromosome 19 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:24991]	-	-	-	-	-	-	-	--
ENSG00000104980	14.759	13.768	13.302	16.571	14.326	17.37	528	427	364	405	431	442	TIMM44	translocase of inner mitochondrial membrane 44 [Source:HGNC Symbol;Acc:HGNC:17316]	-	-	-	-	GO:0001650//fibrillar center;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0051087//chaperone binding	GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000104983	0.982	1.349	1.991	2.545	2.601	2.361	37	40	48	53	62	39	CCDC61	coiled-coil domain containing 61 [Source:HGNC Symbol;Acc:HGNC:33629]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding	GO:0030030//cell projection organization;GO:0090307//mitotic spindle assembly;GO:0098534//centriole assembly	--
ENSG00000104998	0.49	0.276	0.155	0.088	0.097	0.022	30	17	7	4	5	1	IL27RA	interleukin 27 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:17290]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation	K19598;K19598;K19598	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042022//interleukin-12 receptor complex;GO:0043235//receptor complex;GO:0072536//interleukin-23 receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0042019//interleukin-23 binding;GO:0045509//interleukin-27 receptor activity	GO:0002692//negative regulation of cellular extravasation;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0002829//negative regulation of type 2 immune response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0032700//negative regulation of interleukin-17 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0050830//defense response to Gram-positive bacterium;GO:0070106//interleukin-27-mediated signaling pathway;GO:2000317//negative regulation of T-helper 17 type immune response;GO:2000408//negative regulation of T cell extravasation	--
ENSG00000105011	0.856	1.161	0.657	1.58	1.145	0.981	30	34	17	41	30	25	ASF1B	anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042393//histone binding	GO:0001835//blastocyst hatching;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000105048	0.704	0.289	0.674	0.767	0.384	0.741	8	6	11	8	6	10	TNNT1	"troponin T1, slow skeletal type [Source:HGNC Symbol;Acc:HGNC:11948]"	-	-	-	-	GO:0005829//cytosol;GO:0005861//troponin complex	GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0031014//troponin T binding	GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0014883//transition between fast and slow fiber;GO:0030049//muscle filament sliding;GO:0031444//slow-twitch skeletal muscle fiber contraction;GO:0045214//sarcomere organization;GO:0045932//negative regulation of muscle contraction	--
ENSG00000105053	18.659	22.167	20.509	22.525	25.401	20.874	729	830.05	579	634	773	532	VRK3	VRK serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:18996]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0019903//protein phosphatase binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000105058	53.973	56.902	53.254	47.536	47.176	47.115	1604	1691	1157	1047	1180	1014	FAM32A	family with sequence similarity 32 member A [Source:HGNC Symbol;Acc:HGNC:24563]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0008150//biological_process	--
ENSG00000105063	25.549	27.158	27.264	31.73	32.048	31.367	2084	2198	1664	1927	2217	1886	PPP6R1	protein phosphatase 6 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:29195]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0031267//small GTPase binding	GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000105072	3.255	4.426	3.201	3.095	2.684	2.855	215.17	234.62	132.9	131.56	141.7	137.51	C19orf44	chromosome 19 open reading frame 44 [Source:HGNC Symbol;Acc:HGNC:26141]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000105085	3.299	4.072	4.561	3.201	3.335	3.054	189	234	191	156	180	141	MED26	mediator complex subunit 26 [Source:HGNC Symbol;Acc:HGNC:2376]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000105088	17.947	18.412	18.755	19.293	16.522	15.607	728	759	559	565	551	460	OLFM2	olfactomedin 2 [Source:HGNC Symbol;Acc:HGNC:17189]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0009306//protein secretion;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:1905174//regulation of vascular associated smooth muscle cell dedifferentiation	--
ENSG00000105122	0.015	0.033	0.089	0	0.093	0.02	1	1	2	0	3	1	RASAL3	RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17634	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0098562//cytoplasmic side of membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0051142//positive regulation of NK T cell proliferation	--
ENSG00000105127	4.931	5.579	5.916	4.763	5.633	5.705	375	427	333	269	362	316	AKAP8	A-kinase anchoring protein 8 [Source:HGNC Symbol;Acc:HGNC:378]	-	-	-	-	GO:0000793//condensed chromosome;GO:0001939//female pronucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016363//nuclear matrix	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding	GO:0000278//mitotic cell cycle;GO:0002376//immune system process;GO:0007076//mitotic chromosome condensation;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0031065//positive regulation of histone deacetylation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033127//regulation of histone phosphorylation;GO:0044839//cell cycle G2/M phase transition;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide;GO:0071380//cellular response to prostaglandin E stimulus	--
ENSG00000105131	1.515	1.355	1.622	1.091	2.28	1.442	56	51	44	29	58	39	EPHX3	epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation	K22368;K22368	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0004301//epoxide hydrolase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0097176//epoxide metabolic process	--
ENSG00000105135	162.422	158.564	204.89	265.879	232.926	260.694	4842	5059	4639	6009	5900	5490	ILVBL	ilvB acetolactate synthase like [Source:HGNC Symbol;Acc:HGNC:6041]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005948//acetolactate synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000287//magnesium ion binding;GO:0003674//molecular_function;GO:0003824//catalytic activity;GO:0003984//acetolactate synthase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0030976//thiamine pyrophosphate binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding	GO:0001561//fatty acid alpha-oxidation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009097//isoleucine biosynthetic process;GO:0009099//valine biosynthetic process	--
ENSG00000105136	3.637	3.708	4.224	4.899	3.849	4.02	151.44	176.96	107.9	129.55	148	131.55	ZNF419	zinc finger protein 419 [Source:HGNC Symbol;Acc:HGNC:20648]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000105137	18.113	19.125	30.132	25.127	25.511	31.674	1220	1199	1016	1099	1159	1197	SYDE1	synapse defective Rho GTPase homolog 1 [Source:HGNC Symbol;Acc:HGNC:25824]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0030695//GTPase regulator activity	GO:0007165//signal transduction;GO:0016477//cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0051493//regulation of cytoskeleton organization;GO:0090630//activation of GTPase activity;GO:1901165//positive regulation of trophoblast cell migration	--
ENSG00000105141	0	0	0	0	0.054	0	0	0	0	0	3	0	CASP14	caspase 14 [Source:HGNC Symbol;Acc:HGNC:1502]	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0045095//keratin filament	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0006508//proteolysis;GO:0008544//epidermis development;GO:0030154//cell differentiation;GO:0031424//keratinization;GO:0070268//cornification;GO:0097194//execution phase of apoptosis	--
ENSG00000105143	0	0	0	0.076	0.057	0	0	0	0	2	2	0	SLC1A6	solute carrier family 1 member 6 [Source:HGNC Symbol;Acc:HGNC:10944]	Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Nervous system;Nervous system	ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle	K05617;K05617;K05617	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045111//intermediate filament cytoskeleton;GO:0045202//synapse;GO:0098796//membrane protein complex;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0046872//metal ion binding	GO:0001504//neurotransmitter uptake;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0007268//chemical synaptic transmission;GO:0015711//organic anion transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015810//aspartate transmembrane transport;GO:0015813//L-glutamate transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0070778//L-aspartate transmembrane transport;GO:0098712//L-glutamate import across plasma membrane;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000105146	0.431	0.66	0.567	0.579	0.31	0.306	8	14	8	10	5	5	AURKC	aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0030496//midbody;GO:0031616//spindle pole centrosome;GO:0032133//chromosome passenger complex;GO:0051233//spindle midzone"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035174//histone serine kinase activity;GO:0106310//protein serine kinase activity	GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007283//spermatogenesis;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0016310//phosphorylation;GO:0016570//histone modification;GO:0032465//regulation of cytokinesis;GO:0032467//positive regulation of cytokinesis;GO:0035404//histone-serine phosphorylation;GO:0048599//oocyte development;GO:0051255//spindle midzone assembly;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division;GO:0051321//meiotic cell cycle	--
ENSG00000105171	11.194	10.847	8.557	8.81	12.909	9.845	436	450	304	295	403	305	POP4	"POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081]"	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K03538	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030677//ribonuclease P complex;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0008033//tRNA processing;GO:0034470//ncRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000105173	1.124	2.157	1.796	2.032	1.489	1.725	38	78	40	61	51	41	CCNE1	cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: viral;Cell growth and death;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko05226//Gastric cancer;ko05162//Measles;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko05215//Prostate cancer;ko05222//Small cell lung cancer;ko04115//p53 signaling pathway	K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0097134//cyclin E1-CDK2 complex	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000723//telomere maintenance;GO:0006270//DNA replication initiation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007129//homologous chromosome pairing at meiosis;GO:0016055//Wnt signaling pathway;GO:0032880//regulation of protein localization;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:1902462//positive regulation of mesenchymal stem cell proliferation	--
ENSG00000105176	21.652	19.179	16.809	18.484	23.744	17.642	1041	907	609	658	723	622	URI1	URI1 prefoldin like chaperone [Source:HGNC Symbol;Acc:HGNC:13236]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030425//dendrite;GO:0042995//cell projection;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0000993//RNA polymerase II complex binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019212//phosphatase inhibitor activity;GO:0051219//phosphoprotein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009615//response to virus;GO:0010923//negative regulation of phosphatase activity;GO:0050821//protein stabilization;GO:0071363//cellular response to growth factor stimulus;GO:0071383//cellular response to steroid hormone stimulus;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000105185	15.645	13.851	17.42	15.86	11.825	15.578	203	176	167	151	128	148	PDCD5	programmed cell death 5 [Source:HGNC Symbol;Acc:HGNC:8764]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0010698//acetyltransferase activator activity;GO:0048487//beta-tubulin binding	GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1903638//positive regulation of protein insertion into mitochondrial outer membrane;GO:1903645//negative regulation of chaperone-mediated protein folding	--
ENSG00000105186	5.64	4.675	5.604	5.194	5.772	7.338	438.96	395	335	302	401	433	ANKRD27	ankyrin repeat domain 27 [Source:HGNC Symbol;Acc:HGNC:25310]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097422//tubular endosome	GO:0000149//SNARE binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0010976//positive regulation of neuron projection development;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0035544//negative regulation of SNARE complex assembly;GO:0035646//endosome to melanosome transport;GO:0045022//early endosome to late endosome transport;GO:0048812//neuron projection morphogenesis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050790//regulation of catalytic activity	--
ENSG00000105193	436.932	460.497	458.21	540.404	446.269	449.068	5665	6009	4396	5207	4908	4243	RPS16	ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:10396]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02960;K02960	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042274//ribosomal small subunit biogenesis;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000105197	22.021	24.602	24.28	29.48	22.796	30.805	712	812	597	717	737	662	TIMM50	translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	GO:0001836//release of cytochrome c from mitochondria;GO:0006470//protein dephosphorylation;GO:0006886//intracellular protein transport;GO:0007006//mitochondrial membrane organization;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000105198	0	0	0	0	0	0	0	0	0	0	0	0	LGALS13	galectin 13 [Source:HGNC Symbol;Acc:HGNC:15449]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016604//nuclear body	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006644//phospholipid metabolic process;GO:0006915//apoptotic process;GO:0070234//positive regulation of T cell apoptotic process	--
ENSG00000105202	90.616	95.159	98.311	101.717	105.187	103.219	1588	1659	1270	1306	1527	1299	FBL	fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14563	GO:0001650//fibrillar center;GO:0001652//granular component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0016020//membrane;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome;GO:0070062//extracellular exosome	GO:0001094//TFIID-class transcription factor complex binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0016740//transferase activity;GO:0051117//ATPase binding;GO:1990259//histone-glutamine methyltransferase activity	GO:0000494//box C/D RNA 3'-end processing;GO:0001649//osteoblast differentiation;GO:0006364//rRNA processing;GO:0016074//sno(s)RNA metabolic process;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0048254//snoRNA localization;GO:1990258//histone glutamine methylation	--
ENSG00000105204	19.719	20.425	21.068	23.41	21.425	27.313	796	759	645	653	755	736	DYRK1B	dual specificity tyrosine phosphorylation regulated kinase 1B [Source:HGNC Symbol;Acc:HGNC:3092]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0007520//myoblast fusion;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0060612//adipose tissue development"	--
ENSG00000105205	0	0	0	0	0	0	0	0	0	0	0	0	CLC	Charcot-Leyden crystal galectin [Source:HGNC Symbol;Acc:HGNC:2014]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process	GO:0002667//regulation of T cell anergy;GO:0002724//regulation of T cell cytokine production;GO:0007275//multicellular organism development;GO:0046006//regulation of activated T cell proliferation;GO:0070231//T cell apoptotic process	--
ENSG00000105219	0.846	0.855	0.69	0.398	0.512	0.545	26	30	18	11	16	14	CCNP	cyclin P [Source:HGNC Symbol;Acc:HGNC:25805]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0097124//cyclin A2-CDK2 complex	GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0044772//mitotic cell cycle phase transition	--
ENSG00000105220	163.954	180.316	179.938	218.967	208.909	173.237	6039.98	6729	5055	6107	6598	4548	GPI	glucose-6-phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:4458]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko00500//Starch and sucrose metabolism;ko00030//Pentose phosphate pathway	K01810;K01810;K01810;K01810;K01810;K01810	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0043005//neuron projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0004347//glucose-6-phosphate isomerase activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0016853//isomerase activity;GO:0031625//ubiquitin protein ligase binding;GO:0048029//monosaccharide binding	GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0002639//positive regulation of immunoglobulin production;GO:0005975//carbohydrate metabolic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007599//hemostasis;GO:0007611//learning or memory;GO:0010595//positive regulation of endothelial cell migration;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0033574//response to testosterone;GO:0034101//erythrocyte homeostasis;GO:0035902//response to immobilization stress;GO:0035994//response to muscle stretch;GO:0042593//glucose homeostasis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043278//response to morphine;GO:0043524//negative regulation of neuron apoptotic process;GO:0046686//response to cadmium ion;GO:0051156//glucose 6-phosphate metabolic process	--
ENSG00000105221	155.008	163.956	162.205	147.457	141.842	157.504	7394	7600	5441	5001	5680	5177	AKT2	AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Circulatory system;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Signal transduction;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Endocrine system;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Digestive system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04973//Carbohydrate digestion and absorption"	K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006006//glucose metabolic process;GO:0006417//regulation of translation;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0008643//carbohydrate transport;GO:0010748//negative regulation of long-chain fatty acid import across plasma membrane;GO:0010907//positive regulation of glucose metabolic process;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0031340//positive regulation of vesicle fusion;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0032287//peripheral nervous system myelin maintenance;GO:0032869//cellular response to insulin stimulus;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0045444//fat cell differentiation;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0051726//regulation of cell cycle;GO:0060644//mammary gland epithelial cell differentiation;GO:0065002//intracellular protein transmembrane transport;GO:0071486//cellular response to high light intensity;GO:0072659//protein localization to plasma membrane;GO:0090314//positive regulation of protein targeting to membrane;GO:0090630//activation of GTPase activity;GO:0097473//retinal rod cell apoptotic process;GO:2000147//positive regulation of cell motility	--
ENSG00000105223	283.663	299.041	288.321	280.794	279.667	280.548	10430	11109	8010	7789	8617	7374	PLD3	phospholipase D family member 3 [Source:HGNC Symbol;Acc:HGNC:17158]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism	K16860;K16860;K16860	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004630//phospholipase D activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity	GO:0002376//immune system process;GO:0006259//DNA metabolic process;GO:0006954//inflammatory response;GO:0014902//myotube differentiation;GO:0016042//lipid catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1900015//regulation of cytokine production involved in inflammatory response	--
ENSG00000105227	1.43	1.301	1.469	1.956	2.143	9.716	149	137	114	152	193	174	PRX	periaxin [Source:HGNC Symbol;Acc:HGNC:13797]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008366//axon ensheathment;GO:0032287//peripheral nervous system myelin maintenance;GO:0043484//regulation of RNA splicing	--
ENSG00000105229	3.99	4.439	5.126	4.517	4.425	5.095	254	284	241	213	238	236	PIAS4	protein inhibitor of activated STAT 4 [Source:HGNC Symbol;Acc:HGNC:17002]	Environmental Information Processing;Environmental Information Processing;Genetic Information Processing;Human Diseases	"Signal transduction;Signal transduction;Folding, sorting and degradation;Cardiovascular disease"	ko04064//NF-kappa B signaling pathway;ko04630//JAK-STAT signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko05418//Fluid shear stress and atherosclerosis	K16065;K16065;K16065;K16065	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:1990234//transferase complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061665//SUMO ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001942//hair follicle development;GO:0006302//double-strand break repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016925//protein sumoylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033235//positive regulation of protein sumoylation;GO:0042359//vitamin D metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060887//limb epidermis development;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1905168//positive regulation of double-strand break repair via homologous recombination"	zf-MIZ
ENSG00000105245	8.627	8.654	6.353	6.881	8.944	4.473	394	379	240	262	270	174	NUMBL	NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06057	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0007409//axonogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0019538//protein metabolic process;GO:0021670//lateral ventricle development;GO:0021849//neuroblast division in subventricular zone;GO:0030900//forebrain development;GO:0034332//adherens junction organization;GO:0050769//positive regulation of neurogenesis	--
ENSG00000105246	0.167	0.041	0	0.112	0	0	4	1	0	2	0	0	EBI3	Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04659//Th17 cell differentiation	K24476;K24476	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0019955//cytokine binding;GO:0045523//interleukin-27 receptor binding	GO:0006959//humoral immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0033210//leptin-mediated signaling pathway;GO:0042088//T-helper 1 type immune response;GO:0042098//T cell proliferation;GO:0046641//positive regulation of alpha-beta T cell proliferation	--
ENSG00000105248	9.753	10.826	12.535	10.37	10.129	9.446	286	323	273	228	254	204	YJU2	YJU2 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:25518]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0071006//U2-type catalytic step 1 spliceosome	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000349//generation of catalytic spliceosome for first transesterification step;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator"	--
ENSG00000105251	0	0	0	0.034	0	0	0	0	0	1	0	0	SHD	Src homology 2 domain containing transforming protein D [Source:HGNC Symbol;Acc:HGNC:30633]	-	-	-	-	-	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding	-	--
ENSG00000105254	38.556	44.738	48.031	42.508	40.27	44.905	778	902	712	628	685	661	TBCB	tubulin folding cofactor B [Source:HGNC Symbol;Acc:HGNC:1989]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0030154//cell differentiation	--
ENSG00000105255	3.607	2.748	3.632	2.095	2.156	3.47	136	105	102	59	69	96	FSD1	fibronectin type III and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13745]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032154//cleavage furrow	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding	GO:0007049//cell cycle;GO:0031122//cytoplasmic microtubule organization;GO:0032465//regulation of cytokinesis;GO:0051301//cell division;GO:0051302//regulation of cell division;GO:0060236//regulation of mitotic spindle organization	--
ENSG00000105258	15.964	18.38	18.646	22.599	16.239	16.023	149	182	131	162	138	113	POLR2I	RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03017;K03017	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005730//nucleolus"	GO:0003676//nucleic acid binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0001193//maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006379//mRNA cleavage"	--
ENSG00000105261	0	0	0	0	0	0	0	0	0	0	0	0	OVOL3	ovo like zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:14186]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0009913//epidermal cell differentiation	zf-C2H2
ENSG00000105270	29.429	32.505	31.014	27.547	31.09	30.059	2039	2260	1590	1414	1803	1513	CLIP3	CAP-Gly domain containing linker protein 3 [Source:HGNC Symbol;Acc:HGNC:24314]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0035371//microtubule plus-end;GO:0045121//membrane raft;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0035594//ganglioside binding;GO:0051010//microtubule plus-end binding	GO:0001934//positive regulation of protein phosphorylation;GO:0010828//positive regulation of glucose transmembrane transport;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0031115//negative regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0043065//positive regulation of apoptotic process;GO:0044091//membrane biogenesis;GO:0045444//fat cell differentiation;GO:0045807//positive regulation of endocytosis;GO:0098840//protein transport along microtubule;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000105278	2.038	2.516	1.925	2.234	2.038	2.236	46	70	52	56	54	32	ZFR2	zinc finger RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29189]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0008270//zinc ion binding	-	--
ENSG00000105281	4.46	4.245	3.009	4.843	4.282	12.864	253	223	115	204	211	542	SLC1A5	solute carrier family 1 member 5 [Source:HGNC Symbol;Acc:HGNC:10943]	Organismal Systems;Human Diseases	Digestive system;Cancer: overview	ko04974//Protein digestion and absorption;ko05230//Central carbon metabolism in cancer	K05616;K05616	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015293//symporter activity;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	GO:0006865//amino acid transport;GO:0006868//glutamine transport;GO:0010585//glutamine secretion;GO:0015711//organic anion transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015825//L-serine transport;GO:0046718//viral entry into host cell;GO:0055085//transmembrane transport;GO:0070207//protein homotrimerization;GO:0140009//L-aspartate import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903803//L-glutamine import across plasma membrane	--
ENSG00000105287	10.143	12.459	13.622	16.859	11.739	14.763	680	853	624	688	679	638	PRKD2	protein kinase D2 [Source:HGNC Symbol;Acc:HGNC:17293]	Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Endocrine system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04015//Rap1 signaling pathway;ko04925//Aldosterone synthesis and secretion	K06070;K06070;K06070	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0008219//cell death;GO:0010595//positive regulation of endothelial cell migration;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032743//positive regulation of interleukin-2 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0045785//positive regulation of cell adhesion;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0061154//endothelial tube morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0089700//protein kinase D signaling;GO:1901727//positive regulation of histone deacetylase activity;GO:1902533//positive regulation of intracellular signal transduction;GO:2000573//positive regulation of DNA biosynthetic process;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000105289	4.084	5.077	5.688	5.182	5.343	4.957	260	311	240	219	243	219	TJP3	tight junction protein 3 [Source:HGNC Symbol;Acc:HGNC:11829]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06097	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding	GO:0035633//maintenance of blood-brain barrier;GO:0045216//cell-cell junction organization;GO:0090557//establishment of endothelial intestinal barrier;GO:0098609//cell-cell adhesion;GO:0150105//protein localization to cell-cell junction;GO:1905605//positive regulation of blood-brain barrier permeability	--
ENSG00000105290	96.244	111.433	97.913	134.191	130.625	112.173	4479	5240	3348	4603	5182	3729	APLP1	amyloid beta precursor like protein 1 [Source:HGNC Symbol;Acc:HGNC:597]	-	-	-	-	GO:0005604//basement membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0031694//alpha-2A adrenergic receptor binding;GO:0031695//alpha-2B adrenergic receptor binding;GO:0031696//alpha-2C adrenergic receptor binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0009887//animal organ morphogenesis;GO:0030198//extracellular matrix organization;GO:0030900//forebrain development;GO:0071874//cellular response to norepinephrine stimulus;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000105298	8.028	7.947	7.87	8.819	7.677	8.226	526	561	411	396	417	375	CACTIN	"cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001933//negative regulation of protein phosphorylation;GO:0002376//immune system process;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032688//negative regulation of interferon-beta production;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045292//mRNA cis splicing, via spliceosome;GO:0045824//negative regulation of innate immune response;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor"	--
ENSG00000105321	23.039	22.87	17.633	20.588	18.556	18.682	602	645	443	442	497	439	CCDC9	coiled-coil domain containing 9 [Source:HGNC Symbol;Acc:HGNC:24560]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000105323	95.827	96.829	100.037	100.788	95.979	94.342	6794	6826	5064	5158	5744	4940	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U like 1 [Source:HGNC Symbol;Acc:HGNC:17011]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K15047	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0006396//RNA processing;GO:0009615//response to virus	--
ENSG00000105325	11.589	13.002	14.711	15.502	14.721	12.225	760	837	679	727	773	596	FZR1	fizzy and cell division cycle 20 related 1 [Source:HGNC Symbol;Acc:HGNC:24824]	Genetic Information Processing;Cellular Processes;Organismal Systems	"Folding, sorting and degradation;Cell growth and death;Endocrine system"	ko04120//Ubiquitin mediated proteolysis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03364;K03364;K03364	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0010997//anaphase-promoting complex binding;GO:0097027//ubiquitin-protein transferase activator activity;GO:1990757//ubiquitin ligase activator activity	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007346//regulation of mitotic cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0040020//regulation of meiotic nuclear division;GO:0045732//positive regulation of protein catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0070306//lens fiber cell differentiation;GO:0070979//protein K11-linked ubiquitination;GO:0090344//negative regulation of cell aging;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:1905786//positive regulation of anaphase-promoting complex-dependent catabolic process	--
ENSG00000105327	1.482	0.935	0.884	0.717	0.912	0.987	53	36	25	19	27	27	BBC3	BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Cancer: overview;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cell growth and death	ko05200//Pathways in cancer;ko05016//Huntington disease;ko04390//Hippo signaling pathway;ko05162//Measles;ko04210//Apoptosis;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04215//Apoptosis - multiple species	K10132;K10132;K10132;K10132;K10132;K10132;K10132;K10132;K10132	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0097143//PUMA-BCL-xl complex	GO:0005515//protein binding;GO:0051117//ATPase binding	GO:0001836//release of cytochrome c from mitochondria;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008340//determination of adult lifespan;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032464//positive regulation of protein homooligomerization;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0034976//response to endoplasmic reticulum stress;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045926//negative regulation of growth;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0071456//cellular response to hypoxia;GO:0071479//cellular response to ionizing radiation;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1901998//toxin transport;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000105329	24.609	28.981	22.367	21.516	21.82	18.371	1419	1669	944	919	1063	756	TGFB1	transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: parasitic;Endocrine and metabolic disease;Cancer: specific types;Cardiovascular disease;Infectious disease: viral;Immune disease;Cell growth and death;Signal transduction;Cancer: specific types;Infectious disease: parasitic;Signal transduction;Endocrine system;Cell growth and death;Development and regeneration;Immune system;Immune system;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cardiovascular disease;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune disease;Infectious disease: parasitic	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko05146//Amoebiasis;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05414//Dilated cardiomyopathy;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko05140//Leishmaniasis;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04110//Cell cycle;ko04380//Osteoclast differentiation;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05410//Hypertrophic cardiomyopathy;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05321//Inflammatory bowel disease;ko05144//Malaria	K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375;K13375	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0030424//axon;GO:0031012//extracellular matrix;GO:0043025//neuronal cell body;GO:0062023//collagen-containing extracellular matrix	GO:0005160//transforming growth factor beta receptor binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001570//vasculogenesis;GO:0001657//ureteric bud development;GO:0001666//response to hypoxia;GO:0001763//morphogenesis of a branching structure;GO:0001775//cell activation;GO:0001837//epithelial to mesenchymal transition;GO:0001843//neural tube closure;GO:0002028//regulation of sodium ion transport;GO:0002069//columnar/cuboidal epithelial cell maturation;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0002513//tolerance induction to self antigen;GO:0003179//heart valve morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0007406//negative regulation of neuroblast proliferation;GO:0007492//endoderm development;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007568//aging;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008354//germ cell migration;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010033//response to organic substance;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010763//positive regulation of fibroblast migration;GO:0014003//oligodendrocyte development;GO:0014008//positive regulation of microglia differentiation;GO:0014070//response to organic cyclic compound;GO:0016202//regulation of striated muscle tissue development;GO:0021915//neural tube development;GO:0030217//T cell differentiation;GO:0030279//negative regulation of ossification;GO:0030308//negative regulation of cell growth;GO:0030316//osteoclast differentiation;GO:0030879//mammary gland development;GO:0031065//positive regulation of histone deacetylation;GO:0031100//animal organ regeneration;GO:0031536//positive regulation of exit from mitosis;GO:0032355//response to estradiol;GO:0032667//regulation of interleukin-23 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032943//mononuclear cell proliferation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033280//response to vitamin D;GO:0034616//response to laminar fluid shear stress;GO:0035066//positive regulation of histone acetylation;GO:0035902//response to immobilization stress;GO:0042060//wound healing;GO:0042110//T cell activation;GO:0042127//regulation of cell population proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0042306//regulation of protein import into nucleus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042482//positive regulation of odontogenesis;GO:0042552//myelination;GO:0043011//myeloid dendritic cell differentiation;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043129//surfactant homeostasis;GO:0045066//regulatory T cell differentiation;GO:0045589//regulation of regulatory T cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046716//muscle cell cellular homeostasis;GO:0048146//positive regulation of fibroblast proliferation;GO:0048286//lung alveolus development;GO:0048535//lymph node development;GO:0048565//digestive tract development;GO:0048839//inner ear development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050765//negative regulation of phagocytosis;GO:0050777//negative regulation of immune response;GO:0050832//defense response to fungus;GO:0050868//negative regulation of T cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051098//regulation of binding;GO:0051101//regulation of DNA binding;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0051726//regulation of cell cycle;GO:0051781//positive regulation of cell division;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055091//phospholipid homeostasis;GO:0060325//face morphogenesis;GO:0060364//frontal suture morphogenesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060435//bronchiole development;GO:0060744//mammary gland branching involved in thelarche;GO:0060751//branch elongation involved in mammary gland duct branching;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0061035//regulation of cartilage development;GO:0061448//connective tissue development;GO:0070166//enamel mineralization;GO:0070168//negative regulation of biomineral tissue development;GO:0070306//lens fiber cell differentiation;GO:0071260//cellular response to mechanical stimulus;GO:0071363//cellular response to growth factor stimulus;GO:0071479//cellular response to ionizing radiation;GO:0071549//cellular response to dexamethasone stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071677//positive regulation of mononuclear cell migration;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0085029//extracellular matrix assembly;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0097421//liver regeneration;GO:0098586//cellular response to virus;GO:1900182//positive regulation of protein localization to nucleus;GO:1902074//response to salt;GO:1903911//positive regulation of receptor clustering;GO:1905313//transforming growth factor beta receptor signaling pathway involved in heart development;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:1990402//embryonic liver development;GO:2000249//regulation of actin cytoskeleton reorganization"	--
ENSG00000105339	2.207	3.039	2.614	4.93	4.834	5.554	201	233	155	289	275	244	DENND3	DENN domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29134]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0008333//endosome to lysosome transport;GO:0032483//regulation of Rab protein signal transduction;GO:0044257//cellular protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000105341	18.684	20.847	21.847	24.908	23.894	25.594	638	667	530	595	655	578	DMAC2	distal membrane arm assembly component 2 [Source:HGNC Symbol;Acc:HGNC:25496]	-	-	-	-	GO:0005739//mitochondrion;GO:0005747//mitochondrial respiratory chain complex I;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000105352	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM4	CEA cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:1816]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006909//phagocytosis	--
ENSG00000105355	24.167	25.261	24.177	25.594	22.894	23.078	1046	1113	762	824	836	736	PLIN3	perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030133//transport vesicle	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0010890//positive regulation of sequestering of triglyceride;GO:0016192//vesicle-mediated transport;GO:0019915//lipid storage;GO:0042149//cellular response to glucose starvation;GO:1905691//lipid droplet disassembly	--
ENSG00000105357	6.304	6.043	7.348	6.766	6.653	5.422	890	857	634	691	739	503	MYH14	myosin heavy chain 14 [Source:HGNC Symbol;Acc:HGNC:23212]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Circulatory system	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04530//Tight junction;ko04270//Vascular smooth muscle contraction	K10352;K10352;K10352;K10352	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005903//brush border;GO:0016020//membrane;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030424//axon;GO:0030426//growth cone;GO:0042641//actomyosin;GO:0070062//extracellular exosome;GO:0097513//myosin II filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0007519//skeletal muscle tissue development;GO:0007605//sensory perception of sound;GO:0008360//regulation of cell shape;GO:0019228//neuronal action potential;GO:0030048//actin filament-based movement;GO:0031032//actomyosin structure organization;GO:0070584//mitochondrion morphogenesis;GO:0071625//vocalization behavior	--
ENSG00000105364	21.322	21.563	23.448	25.456	25.401	26.745	541	553	448	472	548	486	MRPL4	mitochondrial ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:14276]	Genetic Information Processing	Translation	ko03010//Ribosome	K02926	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000105366	0	0	0	0	0.044	0	0	0	0	0	1	0	SIGLEC8	sialic acid binding Ig like lectin 8 [Source:HGNC Symbol;Acc:HGNC:10877]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion;GO:0007165//signal transduction	--
ENSG00000105369	0.483	0.567	0.297	0.888	0.675	0.844	11	13	5	15	13	14	CD79A	CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698]	Organismal Systems;Human Diseases	Immune system;Immune disease	ko04662//B cell receptor signaling pathway;ko05340//Primary immunodeficiency	K06506;K06506	GO:0005771//multivesicular body;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019815//B cell receptor complex;GO:0045121//membrane raft	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0030183//B cell differentiation;GO:0042100//B cell proliferation;GO:0042113//B cell activation;GO:0050853//B cell receptor signaling pathway	--
ENSG00000105370	0	0	0.075	0.289	0	0.135	0	0	1	4	0	2	LIM2	lens intrinsic membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:6610]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031982//vesicle	GO:0005212//structural constituent of eye lens	GO:0002088//lens development in camera-type eye;GO:0007043//cell-cell junction assembly;GO:0043010//camera-type eye development	--
ENSG00000105371	0.041	0.035	0.202	0.055	0.049	0	1	1	4	1	1	0	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) [Source:HGNC Symbol;Acc:HGNC:5347]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000105372	267.934	289.419	274.649	280.72	250.654	225.29	3184	3448	2417	2486	2529	1994	RPS19	ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02966;K02966	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding	"GO:0000028//ribosomal small subunit assembly;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0002548//monocyte chemotaxis;GO:0006364//rRNA processing;GO:0006412//translation;GO:0007000//nucleolus organization;GO:0009991//response to extracellular stimulus;GO:0030218//erythrocyte differentiation;GO:0030490//maturation of SSU-rRNA;GO:0031640//killing of cells of other organism;GO:0042274//ribosomal small subunit biogenesis;GO:0050829//defense response to Gram-negative bacterium;GO:0051272//positive regulation of cellular component movement;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide"	--
ENSG00000105373	161.527	168.164	166.144	180.718	169.99	153.25	5039	5273	3828	4176	4473	3385	NOP53	NOP53 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:4333]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0033553//rDNA heterochromatin;GO:0043231//intracellular membrane-bounded organelle	GO:0002039//p53 binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008097//5S rRNA binding;GO:0042802//identical protein binding	GO:0000027//ribosomal large subunit assembly;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001932//regulation of protein phosphorylation;GO:0006281//DNA repair;GO:0006364//rRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0039535//regulation of RIG-I signaling pathway;GO:0042254//ribosome biogenesis;GO:0042981//regulation of apoptotic process;GO:0050821//protein stabilization;GO:0051726//regulation of cell cycle;GO:0051898//negative regulation of protein kinase B signaling;GO:0071456//cellular response to hypoxia;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:1901837//negative regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1902570//protein localization to nucleolus;GO:1903006//positive regulation of protein K63-linked deubiquitination;GO:1903715//regulation of aerobic respiration;GO:1990173//protein localization to nucleoplasm	--
ENSG00000105374	0	0	0	0	0	0	0	0	0	0	0	0	NKG7	natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830]	-	-	-	-	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044194//cytolytic granule;GO:0101004//cytolytic granule membrane	GO:0005515//protein binding	"GO:0002420//natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042832//defense response to protozoan;GO:0043320//natural killer cell degranulation;GO:0050729//positive regulation of inflammatory response;GO:0140507//granzyme-mediated programmed cell death signaling pathway"	--
ENSG00000105376	0.923	0.95	0.797	0.245	0.358	0.459	58	60	37	11	19	21	ICAM5	intercellular adhesion molecule 5 [Source:HGNC Symbol;Acc:HGNC:5348]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071944//cell periphery	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000105379	39.688	42.341	41.299	53.122	46.967	50.564	746.99	793.73	571	736	735.63	680	ETFB	electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045251//electron transfer flavoprotein complex	GO:0005515//protein binding;GO:0009055//electron transfer activity	GO:0009063//cellular amino acid catabolic process;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase	--
ENSG00000105383	0	0	0	0	0	0	0	0	0	0	0	0	CD33	CD33 molecule [Source:HGNC Symbol;Acc:HGNC:1659]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06473	GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0038023//signaling receptor activity	GO:0002765//immune response-inhibiting signal transduction;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008285//negative regulation of cell population proliferation;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0050714//positive regulation of protein secretion;GO:0051926//negative regulation of calcium ion transport;GO:0098609//cell-cell adhesion;GO:0150102//negative regulation of monocyte activation;GO:1903615//positive regulation of protein tyrosine phosphatase activity	--
ENSG00000105388	0	0	0	0	0.026	0	0	0	0	0	1	0	CEACAM5	CEA cell adhesion molecule 5 [Source:HGNC Symbol;Acc:HGNC:1817]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome;GO:0071575//integral component of external side of plasma membrane	GO:0005515//protein binding;GO:0034235//GPI anchor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0010832//negative regulation of myotube differentiation;GO:0034109//homotypic cell-cell adhesion;GO:0043066//negative regulation of apoptotic process;GO:2000811//negative regulation of anoikis	--
ENSG00000105392	6.736	7.434	5.112	3.211	4.157	2.451	437	547.14	279	148	252	121	CRX	cone-rod homeobox [Source:HGNC Symbol;Acc:HGNC:2383]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0043522//leucine zipper domain binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050896//response to stimulus"	TF_Otx
ENSG00000105393	50.486	58.971	59.494	62.524	57.604	51.879	1318	1466	1159	1216	1213	992	BABAM1	BRISC and BRCA1 A complex member 1 [Source:HGNC Symbol;Acc:HGNC:25008]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K20776	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0070531//BRCA1-A complex;GO:0070552//BRISC complex	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045739//positive regulation of DNA repair;GO:0051301//cell division;GO:0070536//protein K63-linked deubiquitination;GO:0070537//histone H2A K63-linked deubiquitination	--
ENSG00000105397	23.854	23.86	22.03	32.662	24.696	20.898	1596	1663	1279	1279	1525	1236	TYK2	tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system;Infectious disease: parasitic;Immune system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04658//Th1 and Th2 cell differentiation	K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219;K11219	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042022//interleukin-12 receptor complex;GO:0070062//extracellular exosome;GO:0072536//interleukin-23 receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005131//growth hormone receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031702//type 1 angiotensin receptor binding	GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0035556//intracellular signal transduction;GO:0038196//type III interferon signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0051142//positive regulation of NK T cell proliferation;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus;GO:2000318//positive regulation of T-helper 17 type immune response	--
ENSG00000105398	0	0	0	0	0	0	0	0	0	0	0	0	SULT2A1	sulfotransferase family 2A member 1 [Source:HGNC Symbol;Acc:HGNC:11458]	Organismal Systems;Metabolism;Human Diseases	Digestive system;Xenobiotics biodegradation and metabolism;Cancer: overview	ko04976//Bile secretion;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts	K11822;K11822;K11822	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004027//alcohol sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047704//bile-salt sulfotransferase activity;GO:0050294//steroid sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding	GO:0006068//ethanol catabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016042//lipid catabolic process;GO:0030573//bile acid catabolic process;GO:0042403//thyroid hormone metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000105401	48.782	48.672	48.276	53.659	50.053	44.371	1609	1604	1171	1318	1392	1064	CDC37	"cell division cycle 37, HSP90 cochaperone [Source:HGNC Symbol;Acc:HGNC:1735]"	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K09554	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:0101031//chaperone complex;GO:1990565//HSP90-CDC37 chaperone complex	GO:0005515//protein binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding;GO:0097110//scaffold protein binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006457//protein folding;GO:0006605//protein targeting;GO:0010608//posttranscriptional regulation of gene expression;GO:0045859//regulation of protein kinase activity;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization	--
ENSG00000105402	47.234	42.596	42.803	50.639	49.2	48.002	1581	1439	1088	1237	1397	1163	NAPA	NSF attachment protein alpha [Source:HGNC Symbol;Acc:HGNC:7641]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15296	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031201//SNARE complex;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0000149//SNARE binding;GO:0005483//soluble NSF attachment protein activity;GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0044877//protein-containing complex binding	"GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007420//brain development;GO:0010807//regulation of synaptic vesicle priming;GO:0015031//protein transport;GO:0016082//synaptic vesicle priming;GO:0016192//vesicle-mediated transport;GO:0030182//neuron differentiation;GO:0035249//synaptic transmission, glutamatergic;GO:0035494//SNARE complex disassembly;GO:0045176//apical protein localization;GO:0061025//membrane fusion"	--
ENSG00000105404	69.1	70.09	79.367	92.578	79.894	87.31	1073.81	1095	910.92	1065.84	1050	983	RABAC1	Rab acceptor 1 [Source:HGNC Symbol;Acc:HGNC:9794]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0070064//proline-rich region binding	-	--
ENSG00000105409	68.117	72.113	67.054	69.337	66.538	63.18	5153.28	5456	3744.94	3861.5	4239	3466	ATP1A3	ATPase Na+/K+ transporting subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:801]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539	GO:0001917//photoreceptor inner segment;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031090//organelle membrane;GO:0032809//neuronal cell body membrane;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0060342//photoreceptor inner segment membrane;GO:0098984//neuron to neuron synapse;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0001540//amyloid-beta binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0099520//ion antiporter activity involved in regulation of presynaptic membrane potential;GO:1990239//steroid hormone binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0030007//cellular potassium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0060075//regulation of resting membrane potential;GO:0071383//cellular response to steroid hormone stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:1902600//proton transmembrane transport;GO:1903416//response to glycoside;GO:1904646//cellular response to amyloid-beta;GO:1990535//neuron projection maintenance;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000105419	19.446	18.025	17.907	17.651	19.138	18.017	660	671	460	449	547	426	MEIS3	Meis homeobox 3 [Source:HGNC Symbol;Acc:HGNC:29537]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051897//positive regulation of protein kinase B signaling;GO:2001234//negative regulation of apoptotic signaling pathway"	Homeobox
ENSG00000105426	20.356	24.147	21.953	21.547	22.997	24.945	1536	1621	1389	956	1303	1255	PTPRS	protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0035374//chondroitin sulfate binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0010977//negative regulation of neuron projection development;GO:0016043//cellular component organization;GO:0016311//dephosphorylation;GO:0021510//spinal cord development;GO:0021549//cerebellum development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0022038//corpus callosum development;GO:0030517//negative regulation of axon extension;GO:0032687//negative regulation of interferon-alpha production;GO:0032688//negative regulation of interferon-beta production;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0048671//negative regulation of collateral sprouting;GO:0048681//negative regulation of axon regeneration;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0061000//negative regulation of dendritic spine development;GO:0090557//establishment of endothelial intestinal barrier;GO:0099151//regulation of postsynaptic density assembly;GO:0099560//synaptic membrane adhesion	--
ENSG00000105427	0.452	0	0	0	0.214	0.746	5	0	0	0	2	6	CNFN	cornifelin [Source:HGNC Symbol;Acc:HGNC:30183]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0031424//keratinization	--
ENSG00000105428	0	0	0	0	0	0	0	0	0	0	0	0	ZNRF4	zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000105429	23.091	23.584	26.951	25.252	26.349	24.479	4585	4960	3836	3674	4565	3672	MEGF8	multiple EGF like domains 8 [Source:HGNC Symbol;Acc:HGNC:3233]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K23664	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0003143//embryonic heart tube morphogenesis;GO:0007368//determination of left/right symmetry;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0010468//regulation of gene expression;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0035108//limb morphogenesis;GO:0042074//cell migration involved in gastrulation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048704//embryonic skeletal system morphogenesis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0060971//embryonic heart tube left/right pattern formation;GO:0060972//left/right pattern formation;GO:0060976//coronary vasculature development;GO:0061371//determination of heart left/right asymmetry;GO:0071907//determination of digestive tract left/right asymmetry;GO:0097094//craniofacial suture morphogenesis;GO:0097155//fasciculation of sensory neuron axon	--
ENSG00000105438	168.337	174.362	169.753	196.037	187.72	167.681	5410	5635	4031	4669	5096	3923	KDELR1	KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304]	Human Diseases	Infectious disease: bacterial	ko05110//Vibrio cholerae infection	K10949	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005046//KDEL sequence binding;GO:0005515//protein binding;GO:0046923//ER retention sequence binding	"GO:0006621//protein retention in ER lumen;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030217//T cell differentiation;GO:0070231//T cell apoptotic process"	--
ENSG00000105443	20.903	22.439	25.326	26.227	25.26	22.252	915	988	776	839	917	705	CYTH2	cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway	K18441;K18441;K18441;K18441;K18441	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0030426//growth cone;GO:0042995//cell projection	"GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006897//endocytosis;GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000105447	14.894	14.685	13.728	18.007	17.404	16.049	761	740	638	679	728	673	GRWD1	glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0003682//chromatin binding;GO:0003688//DNA replication origin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly	--
ENSG00000105464	0.07	0.009	0.071	0.071	0.041	0.048	8	1	6	6	4	4	GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D [Source:HGNC Symbol;Acc:HGNC:4588]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Neurodegenerative disease;Signal transduction;Substance dependence;Neurodegenerative disease;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212;K05212	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0016595//glutamate binding;GO:0022843//voltage-gated cation channel activity;GO:0022849//glutamate-gated calcium ion channel activity;GO:0038023//signaling receptor activity;GO:0042165//neurotransmitter binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001964//startle response;GO:0006811//ion transport;GO:0007420//brain development;GO:0008344//adult locomotory behavior;GO:0019722//calcium-mediated signaling;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051930//regulation of sensory perception of pain;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098976//excitatory chemical synaptic transmission;GO:1904062//regulation of cation transmembrane transport;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000105467	0	0	0	0	0	0.077	0	0	0	0	0	1	SYNGR4	synaptogyrin 4 [Source:HGNC Symbol;Acc:HGNC:11502]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction	-	-	--
ENSG00000105472	1.823	1.709	2.706	3.455	2.656	2.988	52	49	57	73	64	62	CLEC11A	C-type lectin domain containing 11A [Source:HGNC Symbol;Acc:HGNC:10576]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030246//carbohydrate binding	GO:0001503//ossification;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation	--
ENSG00000105479	0.08	0.142	0.066	0.131	0.115	0	5	9	3.04	6	6	0	ODAD1	outer dynein arm docking complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:26560]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0036157//outer dynein arm;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0036158//outer dynein arm assembly	--
ENSG00000105483	9.883	6.704	8.186	6.849	8.554	6.554	345	303	258	213	252	281	CARD8	caspase recruitment domain family member 8 [Source:HGNC Symbol;Acc:HGNC:17057]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12801	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0061702//inflammasome complex;GO:0072559//NLRP3 inflammasome complex	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0016787//hydrolase activity;GO:0032089//NACHT domain binding;GO:0038187//pattern recognition receptor activity;GO:0042803//protein homodimerization activity;GO:0050700//CARD domain binding;GO:0140608//cysteine-type endopeptidase activator activity	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0012501//programmed cell death;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0097264//self proteolysis;GO:0097340//inhibition of cysteine-type endopeptidase activity;GO:0140374//antiviral innate immune response;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly	--
ENSG00000105486	6.744	5.673	6.91	5.841	5.349	4.909	443	370	333	287	292	191	LIG1	DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K10747;K10747;K10747;K10747	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003909//DNA ligase activity;GO:0003910//DNA ligase (ATP) activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	"GO:0006260//DNA replication;GO:0006266//DNA ligation;GO:0006273//lagging strand elongation;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006287//base-excision repair, gap-filling;GO:0006298//mismatch repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0009653//anatomical structure morphogenesis;GO:0051301//cell division;GO:0071897//DNA biosynthetic process;GO:1903461//Okazaki fragment processing involved in mitotic DNA replication"	--
ENSG00000105492	0	0	0	0	0.016	0	0	0	0	0	1	0	SIGLEC6	sialic acid binding Ig like lectin 6 [Source:HGNC Symbol;Acc:HGNC:10875]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion;GO:0007267//cell-cell signaling	--
ENSG00000105497	2.726	2.306	2.361	2.146	1.829	2.073	341	303	237	216	210.04	205	ZNF175	zinc finger protein 175 [Source:HGNC Symbol;Acc:HGNC:12964]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus"	zf-C2H2
ENSG00000105499	0.664	0.886	0.808	0.463	0.78	2.017	33	46	25	13	34	29	PLA2G4C	phospholipase A2 group IVC [Source:HGNC Symbol;Acc:HGNC:9037]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008374//O-acyltransferase activity;GO:0008970//phospholipase A1 activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006663//platelet activating factor biosynthetic process;GO:0006954//inflammatory response;GO:0007567//parturition;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0035556//intracellular signal transduction;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0046475//glycerophospholipid catabolic process;GO:0140042//lipid droplet formation	--
ENSG00000105507	0	0	0	0	0	0	0	0	0	0	0	0	CABP5	calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction	--
ENSG00000105509	1.54	1.639	1.487	3.283	2.925	3.859	67	72	48	106	108	122	HAS1	hyaluronan synthase 1 [Source:HGNC Symbol;Acc:HGNC:4818]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0050501//hyaluronan synthase activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:0007155//cell adhesion;GO:0010764//negative regulation of fibroblast migration;GO:0030213//hyaluronan biosynthetic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0085029//extracellular matrix assembly	--
ENSG00000105514	3.218	2.93	3.125	2.702	4.162	3.282	283	259	203	176	202.06	210	RAB3D	"RAB3D, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9779]"	Organismal Systems	Digestive system	ko04972//Pancreatic secretion	K07884	GO:0005768//endosome;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0031982//vesicle;GO:0035577//azurophil granule membrane;GO:0042588//zymogen granule;GO:0070062//extracellular exosome;GO:0099503//secretory vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding;GO:0031489//myosin V binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0018125//peptidyl-cysteine methylation;GO:0045453//bone resorption;GO:0072659//protein localization to plasma membrane;GO:1903307//positive regulation of regulated secretory pathway	--
ENSG00000105516	15.463	13.097	16.323	23.679	19.092	20.061	434.51	396.5	343.35	490.8	506.46	453.37	DBP	D-box binding PAR bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:2697]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	TF_bZIP
ENSG00000105518	80.9	84.069	84.339	118.844	100.297	105.868	1340	1413	1042	1449	1419.94	1290	TMEM205	transmembrane protein 205 [Source:HGNC Symbol;Acc:HGNC:29631]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000105519	2.587	3.575	2.419	2.759	1.924	3.451	81.64	105.88	60	69.78	54.5	83.79	CAPS	calcyphosine [Source:HGNC Symbol;Acc:HGNC:1487]	-	-	-	-	GO:0005737//cytoplasm;GO:0031982//vesicle	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0035556//intracellular signal transduction	--
ENSG00000105520	31.171	30.04	32.33	32.635	29.639	29.968	1636	1610	1262	1256	1391	1178	PLPPR2	phospholipid phosphatase related 2 [Source:HGNC Symbol;Acc:HGNC:29566]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042577//lipid phosphatase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation	--
ENSG00000105523	0	0	0	0.016	0	0	0	0	0	1	0	0	FAM83E	family with sequence similarity 83 member E [Source:HGNC Symbol;Acc:HGNC:25972]	-	-	-	-	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007165//signal transduction	--
ENSG00000105538	0.121	0.015	0.163	0.185	0.071	0.083	8	1	8	3	4	4	RASIP1	Ras interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24716]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005911//cell-cell junction;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0051020//GTPase binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0007165//signal transduction;GO:0010507//negative regulation of autophagy;GO:0033625//positive regulation of integrin activation;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0048754//branching morphogenesis of an epithelial tube;GO:1905709//negative regulation of membrane permeability;GO:2000299//negative regulation of Rho-dependent protein serine/threonine kinase activity	--
ENSG00000105549	0	0	0	0	0	0	0	0	0	0	0	0	THEG	theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0051131//chaperone-mediated protein complex assembly	--
ENSG00000105550	0	0	0	0	0.064	0	0	0	0	0	1	0	FGF21	fibroblast growth factor 21 [Source:HGNC Symbol;Acc:HGNC:3678]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Environmental adaptation;Cell motility;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K22429;K22429;K22429;K22429;K22429;K22429;K22429;K22429;K22429;K22429;K22429	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010898//positive regulation of triglyceride catabolic process;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0014823//response to activity;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031667//response to nutrient levels;GO:0046326//positive regulation of glucose import;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0071377//cellular response to glucagon stimulus;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0072577//endothelial cell apoptotic process;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901215//negative regulation of neuron death;GO:1904640//response to methionine;GO:1905599//positive regulation of low-density lipoprotein receptor activity;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000105552	4.551	4.802	6.463	6.521	6.251	5.277	143	163	161	147	186	127	BCAT2	branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins;Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00770//Pantothenate and CoA biosynthesis;ko01210//2-Oxocarboxylic acid metabolism;ko00290//Valine, leucine and isoleucine biosynthesis"	K00826;K00826;K00826;K00826;K00826;K00826;K00826	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0004084//branched-chain-amino-acid transaminase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0050048//L-leucine:2-oxoglutarate aminotransferase activity;GO:0052654//L-leucine transaminase activity;GO:0052655//L-valine transaminase activity;GO:0052656//L-isoleucine transaminase activity	GO:0006549//isoleucine metabolic process;GO:0006550//isoleucine catabolic process;GO:0006551//leucine metabolic process;GO:0006573//valine metabolic process;GO:0006629//lipid metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009081//branched-chain amino acid metabolic process;GO:0009082//branched-chain amino acid biosynthetic process;GO:0009083//branched-chain amino acid catabolic process;GO:0009098//leucine biosynthetic process;GO:0009099//valine biosynthetic process;GO:0010817//regulation of hormone levels;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000105556	6.449	7.739	9.864	10.557	6.729	7.873	368	383	283	305	324	329	MIER2	MIER family member 2 [Source:HGNC Symbol;Acc:HGNC:29210]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation	--
ENSG00000105559	21.752	20.424	22.524	17.749	19.442	18.067	1048	1056	858	696	712	601	PLEKHA4	pleckstrin homology domain containing A4 [Source:HGNC Symbol;Acc:HGNC:14339]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0042802//identical protein binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	"GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000105568	105.115	107.756	108.342	121.319	118.058	116.628	6361	6591	4937	5478	6064	5171	PPP2R1A	protein phosphatase 2 scaffold subunit Aalpha [Source:HGNC Symbol;Acc:HGNC:9302]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation;Signal transduction;Nervous system	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway;ko04350//TGF-beta signaling pathway;ko04730//Long-term depression	K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456	"GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse"	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0046982//protein heterodimerization activity;GO:1990405//protein antigen binding	"GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process;GO:0007059//chromosome segregation;GO:0007143//female meiotic nuclear division;GO:0008380//RNA splicing;GO:0010033//response to organic substance;GO:0019932//second-messenger-mediated signaling;GO:0030111//regulation of Wnt signaling pathway;GO:0030155//regulation of cell adhesion;GO:0030308//negative regulation of cell growth;GO:0040008//regulation of growth;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0043409//negative regulation of MAPK cascade;GO:0045595//regulation of cell differentiation;GO:0050790//regulation of catalytic activity;GO:0051232//meiotic spindle elongation;GO:0051306//mitotic sister chromatid separation;GO:0051754//meiotic sister chromatid cohesion, centromeric;GO:0065003//protein-containing complex assembly;GO:0070262//peptidyl-serine dephosphorylation;GO:1903538//regulation of meiotic cell cycle process involved in oocyte maturation;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000105576	19.471	25.517	23.303	24.81	25.73	22.941	1465	1691	1191	1242	1453	1110	TNPO2	transportin 2 [Source:HGNC Symbol;Acc:HGNC:19998]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K18727	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0031267//small GTPase binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000105583	64.296	74.317	79.932	88.813	80.697	72.865	825.35	958.8	757.67	844.52	875.37	680.49	WDR83OS	WD repeat domain 83 opposite strand [Source:HGNC Symbol;Acc:HGNC:30203]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0044183//protein folding chaperone	GO:0006457//protein folding;GO:0045048//protein insertion into ER membrane	--
ENSG00000105605	0	0	0	0	0	0	0	0	0	0	0	0	CACNG7	calcium voltage-gated channel auxiliary subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:13626]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04872;K04872;K04872;K04872;K04872;K04872;K04872	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032281//AMPA glutamate receptor complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044300//cerebellar mossy fiber;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0016247//channel regulator activity	"GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0019226//transmission of nerve impulse;GO:0034765//regulation of ion transmembrane transport;GO:0043488//regulation of mRNA stability;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099590//neurotransmitter receptor internalization;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1903861//positive regulation of dendrite extension;GO:2000311//regulation of AMPA receptor activity"	--
ENSG00000105607	11.432	9.898	14.163	12.633	16.757	11.522	249	231	192	203	272	155	GCDH	glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism	K00252;K00252;K00252;K00252	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0004361//glutaryl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding"	GO:0006082//organic acid metabolic process;GO:0006568//tryptophan metabolic process;GO:0006629//lipid metabolic process;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046949//fatty-acyl-CoA biosynthetic process	--
ENSG00000105609	0	0	0	0	0	0	0	0	0	0	0	0	LILRB5	leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0032396//inhibitory MHC class I receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000105610	0	0	0	0	0	0	0	0	0	0	0	0	KLF1	Kruppel like factor 1 [Source:HGNC Symbol;Acc:HGNC:6345]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030218//erythrocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060135//maternal process involved in female pregnancy;GO:1901653//cellular response to peptide"	zf-C2H2
ENSG00000105612	39.994	40.058	41.08	34.235	35.787	38.561	1343	1433	1049	914	1072	1023	DNASE2	"deoxyribonuclease 2, lysosomal [Source:HGNC Symbol;Acc:HGNC:2960]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K01158	GO:0005764//lysosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004531//deoxyribonuclease II activity;GO:0016787//hydrolase activity	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006259//DNA metabolic process;GO:0006308//DNA catabolic process;GO:0006309//apoptotic DNA fragmentation;GO:0006807//nitrogen compound metabolic process;GO:0006915//apoptotic process;GO:0030218//erythrocyte differentiation;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0050776//regulation of immune response;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000105613	1.387	0.95	0.681	1.217	1.465	1.116	52	51	27	48	40	45	MAST1	microtubule associated serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:19034]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000105617	3.631	3.334	2.874	3.92	2.314	4.226	104	96	60.81	83.17	56	88.07	LENG1	leukocyte receptor cluster member 1 [Source:HGNC Symbol;Acc:HGNC:15502]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000105618	31.466	35.421	32.496	32.668	28.925	28.796	1023.05	1156.03	877	825	852.08	686.26	PRPF31	pre-mRNA processing factor 31 [Source:HGNC Symbol;Acc:HGNC:15446]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12844	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005687//U4 snRNP;GO:0005690//U4atac snRNP;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:0071339//MLL1 complex;GO:0097526//spliceosomal tri-snRNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030621//U4 snRNA binding;GO:0030622//U4atac snRNA binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0070990//snRNP binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0071166//ribonucleoprotein complex localization"	--
ENSG00000105619	8.1	9.248	8.07	8.605	7.896	7.847	172.95	219.97	139	156	161.92	139.74	TFPT	TCF3 fusion partner [Source:HGNC Symbol;Acc:HGNC:13630]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0031011//Ino80 complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0044877//protein-containing complex binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008584//male gonad development;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0043065//positive regulation of apoptotic process;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0097190//apoptotic signaling pathway;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000105639	0.403	0.307	0.388	0.399	0.318	0.295	45	33	32	33	30	24	JAK3	Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Cellular community - eukaryotes;Immune disease;Immune system;Immune system;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04062//Chemokine signaling pathway;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05162//Measles;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04658//Th1 and Th2 cell differentiation;ko05223//Non-small cell lung cancer	K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218;K11218	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002731//negative regulation of dendritic cell cytokine production;GO:0006468//protein phosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030218//erythrocyte differentiation;GO:0032693//negative regulation of interleukin-10 production;GO:0032695//negative regulation of interleukin-12 production;GO:0035556//intracellular signal transduction;GO:0035771//interleukin-4-mediated signaling pathway;GO:0038110//interleukin-2-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042981//regulation of apoptotic process;GO:0043029//T cell homeostasis;GO:0045087//innate immune response;GO:0045221//negative regulation of FasL production;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0050868//negative regulation of T cell activation;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051928//positive regulation of calcium ion transport;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0070232//regulation of T cell apoptotic process;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0070669//response to interleukin-2;GO:0070670//response to interleukin-4;GO:0070672//response to interleukin-15;GO:0071104//response to interleukin-9	--
ENSG00000105640	630.824	639.571	676.968	820.056	701.069	640.867	8296	8450	6575	7990	7789	6132	RPL18A	ribosomal protein L18a [Source:HGNC Symbol;Acc:HGNC:10311]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02882;K02882	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0043226//organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000105641	0.013	0	0.018	0.018	0.016	0.074	1	0	1	1	1	4	SLC5A5	solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K14385	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0008507//sodium:iodide symporter activity;GO:0015111//iodide transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006590//thyroid hormone generation;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0015705//iodide transport;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071371//cellular response to gonadotropin stimulus;GO:0150104//transport across blood-brain barrier;GO:1904200//iodide transmembrane transport	--
ENSG00000105642	0.254	0.262	0.128	0.33	0.133	0.148	10	13	7	17	5	8	KCNN1	potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko04911//Insulin secretion;ko04929//GnRH secretion	K04942;K04942	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005242//inward rectifier potassium channel activity;GO:0005516//calmodulin binding;GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0071805//potassium ion transmembrane transport	--
ENSG00000105643	0.871	0.583	0.515	0.697	0.858	0.553	41	29	18	25	33	19	ARRDC2	arrestin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25225]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0015031//protein transport	--
ENSG00000105647	82.928	83.936	90.604	103.94	104.758	93.642	6839.34	6927.68	5508.02	6355.01	7188.81	5581.63	PIK3R2	phosphoinositide-3-kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:8980]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649	"GO:0005634//nucleus;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA"	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030971//receptor tyrosine kinase binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0046982//protein heterodimerization activity	GO:0001678//cellular glucose homeostasis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0010506//regulation of autophagy;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0015031//protein transport;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0032869//cellular response to insulin stimulus;GO:0034976//response to endoplasmic reticulum stress;GO:0042307//positive regulation of protein import into nucleus;GO:0043409//negative regulation of MAPK cascade;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000105649	3.287	2.405	2.662	4.003	3.303	3.853	102	75	61	92	86	87	RAB3A	"RAB3A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9777]"	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04911//Insulin secretion;ko04721//Synaptic vesicle cycle	K07882;K07882	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030424//axon;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm;GO:0048786//presynaptic active zone;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098993//anchored component of synaptic vesicle membrane;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0001671//ATPase activator activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008022//protein C-terminus binding;GO:0030742//GTP-dependent protein binding;GO:0031489//myosin V binding;GO:0051021//GDP-dissociation inhibitor binding;GO:0051117//ATPase binding	GO:0001778//plasma membrane repair;GO:0003016//respiratory system process;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007005//mitochondrion organization;GO:0007274//neuromuscular synaptic transmission;GO:0007409//axonogenesis;GO:0009306//protein secretion;GO:0009791//post-embryonic development;GO:0010807//regulation of synaptic vesicle priming;GO:0014059//regulation of dopamine secretion;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0016188//synaptic vesicle maturation;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0030324//lung development;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0032418//lysosome localization;GO:0036465//synaptic vesicle recycling;GO:0045054//constitutive secretory pathway;GO:0045055//regulated exocytosis;GO:0045921//positive regulation of exocytosis;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048489//synaptic vesicle transport;GO:0048790//maintenance of presynaptic active zone structure;GO:0050975//sensory perception of touch;GO:0051602//response to electrical stimulus;GO:0060478//acrosomal vesicle exocytosis;GO:0061670//evoked neurotransmitter secretion;GO:0072659//protein localization to plasma membrane;GO:0097091//synaptic vesicle clustering;GO:1903307//positive regulation of regulated secretory pathway;GO:1905684//regulation of plasma membrane repair;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000105650	0.17	0.108	0.38	0	0.282	0.221	16.39	5.74	16	0	9.96	1.98	PDE4C	phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782]	Metabolism;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction"	K13293;K13293;K13293;K13293;K13293	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction	--
ENSG00000105655	90.228	84.435	101.187	94.835	88.504	93.092	3576	3497	3034	2865	3107	2748	ISYNA1	inositol-3-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:29821]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism	K01858;K01858	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004512//inositol-3-phosphate synthase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0006021//inositol biosynthetic process;GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process	--
ENSG00000105656	3.622	3.39	3.395	3.151	3.612	3.721	247	244	183	181	242	203	ELL	elongation factor for RNA polymerase II [Source:HGNC Symbol;Acc:HGNC:23114]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0035327//transcriptionally active chromatin;GO:0035363//histone locus body	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0019902//phosphatase binding	"GO:0001701//in utero embryonic development;GO:0006366//transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III;GO:0045945//positive regulation of transcription by RNA polymerase III"	--
ENSG00000105662	5.85	5.63	5.998	5.516	5.967	4.067	450	528	367	392	481	275	CRTC1	CREB regulated transcription coactivator 1 [Source:HGNC Symbol;Acc:HGNC:16062]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K15309	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding	GO:0007613//memory;GO:0032793//positive regulation of CREB transcription factor activity;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051289//protein homotetramerization;GO:0097009//energy homeostasis;GO:0099527//postsynapse to nucleus signaling pathway;GO:1900006//positive regulation of dendrite development;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1902631//negative regulation of membrane hyperpolarization	--
ENSG00000105664	0.084	0.098	0	0.114	0.124	0	4	5	0	4	5	0	COMP	cartilage oligomeric matrix protein [Source:HGNC Symbol;Acc:HGNC:2227]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Transport and catabolism;Cellular community - eukaryotes;Signaling molecules and interaction;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko04510//Focal adhesion;ko04512//ECM-receptor interaction;ko05144//Malaria	K04659;K04659;K04659;K04659;K04659;K04659	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0032991//protein-containing complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0036122//BMP binding;GO:0043394//proteoglycan binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0002063//chondrocyte development;GO:0003416//endochondral bone growth;GO:0003417//growth plate cartilage development;GO:0006915//apoptotic process;GO:0006986//response to unfolded protein;GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0009306//protein secretion;GO:0009887//animal organ morphogenesis;GO:0010259//multicellular organism aging;GO:0010260//animal organ senescence;GO:0010468//regulation of gene expression;GO:0014829//vascular associated smooth muscle contraction;GO:0016485//protein processing;GO:0030199//collagen fibril organization;GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0035264//multicellular organism growth;GO:0035988//chondrocyte proliferation;GO:0035989//tendon development;GO:0043066//negative regulation of apoptotic process;GO:0043588//skin development;GO:0048844//artery morphogenesis;GO:0050881//musculoskeletal movement;GO:0050905//neuromuscular process;GO:0051216//cartilage development;GO:0051260//protein homooligomerization;GO:0055001//muscle cell development;GO:0060173//limb development;GO:0060349//bone morphogenesis;GO:0070527//platelet aggregation;GO:0097084//vascular associated smooth muscle cell development;GO:0098868//bone growth;GO:1900047//negative regulation of hemostasis;GO:1902732//positive regulation of chondrocyte proliferation;GO:1990079//cartilage homeostasis	--
ENSG00000105668	0	0.038	0.258	0.051	0.09	0	0	1	5	1	2	0	UPK1A	uroplakin 1A [Source:HGNC Symbol;Acc:HGNC:12577]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0120001//apical plasma membrane urothelial plaque	GO:0005515//protein binding	GO:0030855//epithelial cell differentiation	--
ENSG00000105669	67.765	68.67	67.565	84.414	71.977	65.35	1580.96	1613	1166.98	1456.97	1409	1107	COPE	COPI coat complex subunit epsilon [Source:HGNC Symbol;Acc:HGNC:2234]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005198//structural molecule activity;GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0099612//protein localization to axon"	--
ENSG00000105671	26.597	26.903	25.056	29.048	28.706	23.63	987	1008	688	771	888	644	DDX49	DEAD-box helicase 49 [Source:HGNC Symbol;Acc:HGNC:18684]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006364//rRNA processing;GO:0030307//positive regulation of cell growth;GO:0044357//regulation of rRNA stability	--
ENSG00000105672	0.663	0.457	0.564	0.291	0.225	0.257	10	8	7	6	3	3	ETV2	ETS variant transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3491]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0001824//blastocyst development;GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0060803//BMP signaling pathway involved in mesodermal cell fate specification;GO:2000382//positive regulation of mesoderm development"	ETS
ENSG00000105675	0	0	0	0	0	0	0	0	0	0	0	0	ATP4A	ATPase H+/K+ transporting subunit alpha [Source:HGNC Symbol;Acc:HGNC:819]	Metabolism;Metabolism;Organismal Systems;Organismal Systems	Global and overview maps;Energy metabolism;Digestive system;Excretory system	ko01100//Metabolic pathways;ko00190//Oxidative phosphorylation;ko04971//Gastric acid secretion;ko04966//Collecting duct acid secretion	K01542;K01542;K01542;K01542	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0008900//P-type potassium:proton transporter activity;GO:0016887//ATP hydrolysis activity;GO:0030955//potassium ion binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0030007//cellular potassium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0071805//potassium ion transmembrane transport;GO:1902600//proton transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000105676	14.715	13.896	15.259	16.704	16.463	14.611	636.56	658	554	554	679	502	ARMC6	armadillo repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:25049]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000105677	117.06	107.152	122.631	150.558	115.256	128.643	2095	1927	1626	2000	1747	1675	TMEM147	transmembrane protein 147 [Source:HGNC Symbol;Acc:HGNC:30414]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0043022//ribosome binding	-	--
ENSG00000105679	0.033	0	0	0	0	0	1	0	0	0	0	0	GAPDHS	"glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864]"	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00010//Glycolysis / Gluconeogenesis	K10705;K10705	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0050661//NADP binding;GO:0051287//NAD binding"	GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0030317//flagellated sperm motility;GO:0045821//positive regulation of glycolytic process	--
ENSG00000105695	0.372	0.186	0.176	0.442	0.508	0.211	12	9	5	16	21	4	MAG	myelin associated glycoprotein [Source:HGNC Symbol;Acc:HGNC:6783]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06771	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033270//paranode region of axon;GO:0035749//myelin sheath adaxonal region;GO:0043209//myelin sheath;GO:0043218//compact myelin;GO:0043220//Schmidt-Lanterman incisure;GO:0045121//membrane raft;GO:0097453//mesaxon	GO:0005102//signaling receptor binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0042803//protein homodimerization activity;GO:1905576//ganglioside GT1b binding	GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0010977//negative regulation of neuron projection development;GO:0019226//transmission of nerve impulse;GO:0021762//substantia nigra development;GO:0022010//central nervous system myelination;GO:0030517//negative regulation of axon extension;GO:0031103//axon regeneration;GO:0031643//positive regulation of myelination;GO:0032289//central nervous system myelin formation;GO:0042552//myelination;GO:0043524//negative regulation of neuron apoptotic process;GO:0045665//negative regulation of neuron differentiation;GO:0048711//positive regulation of astrocyte differentiation;GO:0071260//cellular response to mechanical stimulus;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000105696	0.595	1.036	0.362	0.522	0.387	0.204	20	35	9	13	11	5	TMEM59L	transmembrane protein 59 like [Source:HGNC Symbol;Acc:HGNC:13237]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000105697	0	0	0	0	0	0	0	0	0	0	0	0	HAMP	hepcidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:15598]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K23106	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0014704//intercalated disc;GO:0045179//apical cortex	GO:0005179//hormone activity;GO:0005507//copper ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002262//myeloid cell homeostasis;GO:0006879//cellular iron ion homeostasis;GO:0006953//acute-phase response;GO:0006955//immune response;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007568//aging;GO:0010039//response to iron ion;GO:0010043//response to zinc ion;GO:0031640//killing of cells of other organism;GO:0033189//response to vitamin A;GO:0034760//negative regulation of iron ion transmembrane transport;GO:0036017//response to erythropoietin;GO:0042742//defense response to bacterium;GO:0043032//positive regulation of macrophage activation;GO:0045471//response to ethanol;GO:0045779//negative regulation of bone resorption;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050728//negative regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0055072//iron ion homeostasis;GO:0060586//multicellular organismal iron ion homeostasis;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0071222//cellular response to lipopolysaccharide;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0071481//cellular response to X-ray;GO:0097421//liver regeneration;GO:1903364//positive regulation of cellular protein catabolic process;GO:1903413//cellular response to bile acid;GO:1904479//negative regulation of intestinal absorption;GO:1990641//response to iron ion starvation	--
ENSG00000105698	71.4	70.073	72.585	86.802	81.886	76.203	2360	2335	1801	2167	2283	1866	USF2	"upstream transcription factor 2, c-fos interacting [Source:HGNC Symbol;Acc:HGNC:12594]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007595//lactation;GO:0019086//late viral transcription;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055088//lipid homeostasis"	bHLH
ENSG00000105699	104.946	105.606	96.851	76.071	88.135	78.081	4487	4519	3064	2413	3188	2451	LSR	lipolysis stimulated lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:29572]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0042627//chylomicron;GO:0061689//tricellular tight junction;GO:0070062//extracellular exosome;GO:0070160//tight junction	-	GO:0001889//liver development;GO:0010669//epithelial structure maintenance;GO:0019216//regulation of lipid metabolic process;GO:0035633//maintenance of blood-brain barrier;GO:0060856//establishment of blood-brain barrier;GO:0061436//establishment of skin barrier;GO:0061833//protein localization to tricellular tight junction;GO:1904274//tricellular tight junction assembly	--
ENSG00000105700	17	18.618	16.196	20.695	20.029	16.649	458	493	318	384	424	325	KXD1	KxDL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28420]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0031083//BLOC-1 complex;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex	GO:0005515//protein binding	GO:0016192//vesicle-mediated transport;GO:0032418//lysosome localization;GO:0051036//regulation of endosome size;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule	--
ENSG00000105701	134.687	144.496	142.863	159.582	153.219	137.287	4769	5102	3754	4207	4621	3548	FKBP8	FKBP prolyl isomerase 8 [Source:HGNC Symbol;Acc:HGNC:3724]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0044183//protein folding chaperone;GO:0046872//metal ion binding;GO:0097718//disordered domain specific binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0001708//cell fate specification;GO:0001933//negative regulation of protein phosphorylation;GO:0006457//protein folding;GO:0006915//apoptotic process;GO:0007224//smoothened signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0010468//regulation of gene expression;GO:0021904//dorsal/ventral neural tube patterning;GO:0021915//neural tube development;GO:0030510//regulation of BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0035264//multicellular organism growth;GO:0035556//intracellular signal transduction;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process	--
ENSG00000105705	9.698	9.333	11.571	10.773	9.12	11.831	507	461	367	405	394	389	SUGP1	SURP and G-patch domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18643]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000105707	4.846	4.598	4.123	6.191	5.801	5.398	168	163	109	149	144	131	HPN	hepsin [Source:HGNC Symbol;Acc:HGNC:5155]	Human Diseases	Cancer: overview	ko05203//Viral carcinogenesis	K08665	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031965//nuclear membrane;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070008//serine-type exopeptidase activity	GO:0006508//proteolysis;GO:0008360//regulation of cell shape;GO:0010628//positive regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010756//positive regulation of plasminogen activation;GO:0030307//positive regulation of cell growth;GO:0034769//basement membrane disassembly;GO:0043066//negative regulation of apoptotic process;GO:0043923//positive regulation by host of viral transcription;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0071805//potassium ion transmembrane transport;GO:0090103//cochlea morphogenesis;GO:0097066//response to thyroid hormone;GO:0097195//pilomotor reflex;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000611//positive regulation of thyroid hormone generation	--
ENSG00000105708	2.88	1.862	1.718	1.626	1.81	2.259	177	115	78	74	94	101	ZNF14	zinc finger protein 14 [Source:HGNC Symbol;Acc:HGNC:12924]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000105711	2.22	2.282	1.319	3.499	3.414	4.278	82	88	37	102	103	119	SCN1B	sodium voltage-gated channel beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:10586]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04845	GO:0001518//voltage-gated sodium channel complex;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0030424//axon;GO:0033268//node of Ranvier;GO:0034706//sodium channel complex;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0019871//sodium channel inhibitor activity;GO:0044325//transmembrane transporter binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0086062//voltage-gated sodium channel activity involved in Purkinje myocyte action potential	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0010765//positive regulation of sodium ion transport;GO:0010976//positive regulation of neuron projection development;GO:0019227//neuronal action potential propagation;GO:0021966//corticospinal neuron axon guidance;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0040011//locomotion;GO:0051899//membrane depolarization;GO:0060048//cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0061337//cardiac conduction;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086047//membrane depolarization during Purkinje myocyte cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000105717	0.683	0.506	0.616	0.667	1.184	1.096	20	14	11	14	29	21	PBX4	PBX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:13403]	-	-	-	-	GO:0000785//chromatin;GO:0001741//XY body;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0009887//animal organ morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048568//embryonic organ development;GO:0048666//neuron development"	Homeobox
ENSG00000105722	76.7	69.038	61.719	49.135	57.329	55.095	3444	3586	1940	1905	2522	1917	ERF	ETS2 repressor factor [Source:HGNC Symbol;Acc:HGNC:3444]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	ETS
ENSG00000105723	36.951	34.058	39.272	36.036	36.836	39.633	1460	1476	1253	1166	1355	1258	GSK3A	glycogen synthase kinase 3 alpha [Source:HGNC Symbol;Acc:HGNC:4616]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system;Endocrine and metabolic disease;Nervous system	ko05131//Shigellosis;ko04062//Chemokine signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04728//Dopaminergic synapse	K08822;K08822;K08822;K08822	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030424//axon;GO:0030877//beta-catenin destruction complex;GO:0043025//neuronal cell body;GO:0097440//apical dendrite;GO:0098794//postsynapse;GO:1990635//proximal dendrite	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	"GO:0003073//regulation of systemic arterial blood pressure;GO:0003214//cardiac left ventricle morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007212//dopamine receptor signaling pathway;GO:0007399//nervous system development;GO:0008286//insulin receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010905//negative regulation of UDP-glucose catabolic process;GO:0010975//regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019082//viral protein processing;GO:0031398//positive regulation of protein ubiquitination;GO:0032007//negative regulation of TOR signaling;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0036016//cellular response to interleukin-3;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0045732//positive regulation of protein catabolic process;GO:0045823//positive regulation of heart contraction;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0051093//negative regulation of developmental process;GO:0051128//regulation of cellular component organization;GO:0060079//excitatory postsynaptic potential;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0071879//positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0106071//positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902004//positive regulation of amyloid-beta formation;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1904227//negative regulation of glycogen synthase activity, transferring glucose-1-phosphate;GO:2000077//negative regulation of type B pancreatic cell development;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:2000467//positive regulation of glycogen (starch) synthase activity"	--
ENSG00000105726	36.983	39.852	41.619	50.991	49.626	46.667	2952	3198	2454	3014	3347	2703	ATP13A1	ATPase 13A1 [Source:HGNC Symbol;Acc:HGNC:24215]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0015410//ABC-type manganese transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding;GO:0140567//transmembrane protein dislocase activity	GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis;GO:0015031//protein transport;GO:0034220//ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0098655//cation transmembrane transport;GO:0140569//extraction of mislocalized protein from ER membrane	--
ENSG00000105732	5.534	6.075	6.753	6.831	7.112	7.914	355	391	320	324	387	370	ZNF574	zinc finger protein 574 [Source:HGNC Symbol;Acc:HGNC:26166]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000105737	18.487	20.496	19.775	22.237	21.418	20.43	1376	1544	1140	1239	1392	1147	GRIK5	glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04724//Glutamatergic synapse	K05205;K05205	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity;GO:0017124//SH3 domain binding;GO:0030165//PDZ domain binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006621//protein retention in ER lumen;GO:0006811//ion transport;GO:0007268//chemical synaptic transmission;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0042391//regulation of membrane potential;GO:0043113//receptor clustering;GO:0043525//positive regulation of neuron apoptotic process;GO:0050804//modulation of chemical synaptic transmission;GO:0051649//establishment of localization in cell;GO:0060079//excitatory postsynaptic potential;GO:0071333//cellular response to glucose stimulus"	--
ENSG00000105738	6.699	7.245	7.969	7.262	8.035	6.929	1065	1174	934	893	1127	837	SIPA1L3	signal induced proliferation associated 1 like 3 [Source:HGNC Symbol;Acc:HGNC:23801]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17703	GO:0001725//stress fiber;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0045177//apical part of cell;GO:0061689//tricellular tight junction	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0001654//eye development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003382//epithelial cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090162//establishment of epithelial cell polarity;GO:0090630//activation of GTPase activity	--
ENSG00000105750	3.53	3.261	2.99	2.744	2.47	2.062	119	123	68	69	79	54	ZNF85	zinc finger protein 85 [Source:HGNC Symbol;Acc:HGNC:13160]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000105755	8.144	7.972	8.403	9.247	8.338	8.23	150	148	114	130	134	111	ETHE1	ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K17725;K17725	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050313//sulfur dioxygenase activity;GO:0051213//dioxygenase activity"	GO:0006749//glutathione metabolic process;GO:0070813//hydrogen sulfide metabolic process	--
ENSG00000105767	59.906	63.676	72.166	71.925	65.615	67.471	2720	2906	2420	2419	2517	2229	CADM4	cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:30825]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0044291//cell-cell contact zone	GO:0019903//protein phosphatase binding;GO:0030971//receptor tyrosine kinase binding;GO:0043183//vascular endothelial growth factor receptor 1 binding;GO:0043184//vascular endothelial growth factor receptor 2 binding	GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0035020//regulation of Rac protein signal transduction;GO:0042127//regulation of cell population proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0061041//regulation of wound healing;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:2000145//regulation of cell motility	--
ENSG00000105771	9.414	9.858	11.333	11.326	10.89	10.9	598	619	525	528	578	502	SMG9	SMG9 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:25763]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001654//eye development;GO:0001701//in utero embryonic development;GO:0007420//brain development;GO:0007507//heart development"	--
ENSG00000105778	9.096	8.225	8.524	8.188	7.968	8.806	1290	1176	883	850	958	902	AVL9	AVL9 cell migration associated [Source:HGNC Symbol;Acc:HGNC:28994]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	-	GO:0016477//cell migration	--
ENSG00000105784	0.059	0.082	0.065	0.097	0.088	0.016	5	7	2	3	4	1	RUNDC3B	RUN domain containing 3B [Source:HGNC Symbol;Acc:HGNC:30286]	-	-	-	-	-	-	-	--
ENSG00000105792	1.134	0.714	0.725	0.645	1.049	1.235	77	56	36	19	37	35	CFAP69	cilia and flagella associated protein 69 [Source:HGNC Symbol;Acc:HGNC:26107]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097225//sperm midpiece;GO:0097730//non-motile cilium	-	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0007608//sensory perception of smell;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0042048//olfactory behavior;GO:0050896//response to stimulus;GO:1902093//positive regulation of flagellated sperm motility;GO:1905516//positive regulation of fertilization;GO:1990834//response to odorant	--
ENSG00000105793	3.367	5.208	2.999	3.925	3.609	3.235	277	273	190	156	219	143	GTPBP10	GTP binding protein 10 [Source:HGNC Symbol;Acc:HGNC:25106]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0042254//ribosome biogenesis	--
ENSG00000105808	1.997	1.948	1.753	2.586	1.598	1.522	178.32	188.4	119.48	146.46	91.17	127.44	RASA4	RAS p21 protein activator 4 [Source:HGNC Symbol;Acc:HGNC:23181]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17630	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0034260//negative regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0071277//cellular response to calcium ion	--
ENSG00000105810	7.303	5.816	5.523	5.723	6.295	5.952	1759	1409	984	1022	1282	1043	CDK6	cyclin dependent kinase 6 [Source:HGNC Symbol;Acc:HGNC:1777]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: specific types;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05162//Measles;ko04110//Cell cycle;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway	K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091;K02091	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016592//mediator complex;GO:0042995//cell projection;GO:0097132//cyclin D2-CDK6 complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0098770//FBXO family protein binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003323//type B pancreatic cell development;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007219//Notch signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0014002//astrocyte development;GO:0016310//phosphorylation;GO:0021542//dentate gyrus development;GO:0021670//lateral ventricle development;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0042063//gliogenesis;GO:0042127//regulation of cell population proliferation;GO:0043697//cell dedifferentiation;GO:0045596//negative regulation of cell differentiation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045646//regulation of erythrocyte differentiation;GO:0045656//negative regulation of monocyte differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045786//negative regulation of cell cycle;GO:0048146//positive regulation of fibroblast proliferation;GO:0048699//generation of neurons;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060218//hematopoietic stem cell differentiation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:2000145//regulation of cell motility;GO:2000773//negative regulation of cellular senescence	--
ENSG00000105819	25.431	25.221	22.082	22.835	21.22	22.956	1034.48	985.18	682.21	695.8	743.88	719.71	PMPCB	"peptidase, mitochondrial processing subunit beta [Source:HGNC Symbol;Acc:HGNC:9119]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0017087//mitochondrial processing peptidase complex	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0016485//protein processing	--
ENSG00000105821	3.592	3.238	2.159	1.828	2.294	2.892	146.52	129.82	72.79	56.2	83.12	74.29	DNAJC2	DnaJ heat shock protein family (Hsp40) member C2 [Source:HGNC Symbol;Acc:HGNC:13192]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0001671//ATPase activator activity;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0042393//histone binding;GO:0043022//ribosome binding;GO:0061649//ubiquitin modification-dependent histone binding	"GO:0006260//DNA replication;GO:0006325//chromatin organization;GO:0006450//regulation of translational fidelity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051083//'de novo' cotranslational protein folding;GO:1900034//regulation of cellular response to heat;GO:2000279//negative regulation of DNA biosynthetic process"	MYB
ENSG00000105825	324.665	325.262	349.32	423.752	385.587	385.301	11089	11002	8609	10323	10771	9392	TFPI2	tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent;GO:0030414//peptidase inhibitor activity	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0071498//cellular response to fluid shear stress	--
ENSG00000105829	20.692	19.634	20.601	18.162	15.816	17.526	576	565	431	387	411	347	BET1	Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08504	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0031201//SNARE complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0098791//Golgi apparatus subcompartment	GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0048280//vesicle fusion with Golgi apparatus	--
ENSG00000105835	20.14	16.98	17.458	15.142	14.677	17.584	1046	845	606	566	644	694	NAMPT	nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Immune system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04621//NOD-like receptor signaling pathway;ko00760//Nicotinate and nicotinamide metabolism	K03462;K03462;K03462	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0047280//nicotinamide phosphoribosyltransferase activity	GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007623//circadian rhythm;GO:0008284//positive regulation of cell population proliferation;GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process;GO:0032922//circadian regulation of gene expression;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process	--
ENSG00000105849	4.656	3.585	4.259	2.943	3.137	3.693	376	291	254	176	214	217	POLR1F	RNA polymerase I subunit F [Source:HGNC Symbol;Acc:HGNC:18027]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K03004	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex	GO:0003899//DNA-directed 5'-3' RNA polymerase activity	"GO:0006352//DNA-templated transcription, initiation;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000105851	0	0	0	0	0	0	0	0	0	0	0	0	PIK3CG	"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:8978]"	Metabolism;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Immune system;Signal transduction;Endocrine system;Circulatory system;Signal transduction;Immune system;Nervous system;Infectious disease: parasitic;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko05132//Salmonella infection;ko04072//Phospholipase D signaling pathway;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04611//Platelet activation;ko04725//Cholinergic synapse;ko05145//Toxoplasmosis;ko00562//Inositol phosphate metabolism	K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289;K21289	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0016020//membrane"	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0042802//identical protein binding;GO:0046875//ephrin receptor binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0106310//protein serine kinase activity"	GO:0001525//angiogenesis;GO:0001819//positive regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002407//dendritic cell chemotaxis;GO:0002675//positive regulation of acute inflammatory response;GO:0002679//respiratory burst involved in defense response;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010595//positive regulation of endothelial cell migration;GO:0010818//T cell chemotaxis;GO:0010897//negative regulation of triglyceride catabolic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030593//neutrophil chemotaxis;GO:0032252//secretory granule localization;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0035022//positive regulation of Rac protein signal transduction;GO:0035747//natural killer cell chemotaxis;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0042098//T cell proliferation;GO:0042110//T cell activation;GO:0043085//positive regulation of catalytic activity;GO:0043303//mast cell degranulation;GO:0043406//positive regulation of MAP kinase activity;GO:0044238//primary metabolic process;GO:0045087//innate immune response;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0055118//negative regulation of cardiac muscle contraction;GO:0070527//platelet aggregation;GO:0071320//cellular response to cAMP;GO:0072672//neutrophil extravasation;GO:0097284//hepatocyte apoptotic process;GO:1903169//regulation of calcium ion transmembrane transport;GO:2000270//negative regulation of fibroblast apoptotic process	--
ENSG00000105852	0.283	0.229	0.274	0.982	0.383	0.243	7	5	5	17	8	4	PON3	paraoxonase 3 [Source:HGNC Symbol;Acc:HGNC:9206]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004063//aryldialkylphosphatase activity;GO:0004064//arylesterase activity;GO:0016787//hydrolase activity;GO:0018733//3,4-dihydrocoumarin hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0102007//acyl-L-homoserine-lactone lactonohydrolase activity"	GO:0003096//renal sodium ion transport;GO:0009636//response to toxic substance;GO:0010124//phenylacetate catabolic process;GO:0016311//dephosphorylation;GO:0019439//aromatic compound catabolic process;GO:0032929//negative regulation of superoxide anion generation;GO:0046226//coumarin catabolic process;GO:0046395//carboxylic acid catabolic process;GO:0051649//establishment of localization in cell	--
ENSG00000105854	37.082	34.117	34.691	30.894	29.464	32.479	1214	1139	867	772	829	774	PON2	paraoxonase 2 [Source:HGNC Symbol;Acc:HGNC:9205]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004064//arylesterase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0102007//acyl-L-homoserine-lactone lactonohydrolase activity	GO:0006979//response to oxidative stress;GO:0009636//response to toxic substance;GO:0019439//aromatic compound catabolic process	--
ENSG00000105855	61.043	38.872	41.091	27.034	33.725	34.354	11202	7201	5570	3711	5183	4583	ITGB8	integrin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:6163]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06591;K06591;K06591;K06591;K06591;K06591;K06591;K06591;K06591	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034686//integrin alphav-beta8 complex;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0038023//signaling receptor activity;GO:1990430//extracellular matrix protein binding	GO:0001570//vasculogenesis;GO:0001573//ganglioside metabolic process;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016477//cell migration;GO:0033627//cell adhesion mediated by integrin;GO:0045766//positive regulation of angiogenesis;GO:0051216//cartilage development;GO:0060022//hard palate development;GO:0060674//placenta blood vessel development;GO:0061520//Langerhans cell differentiation;GO:1901388//regulation of transforming growth factor beta activation	--
ENSG00000105856	33.856	30.133	27.448	25.394	25.091	21.322	1682.56	1660.92	1101.62	968.45	1189.56	872.41	HBP1	HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016055//Wnt signaling pathway;GO:0051726//regulation of cell cycle"	HMG
ENSG00000105865	1.992	2.099	1.856	1.906	2.068	1.744	79.62	84.57	56.49	58.91	72.85	56.82	DUS4L	dihydrouridine synthase 4 like [Source:HGNC Symbol;Acc:HGNC:21517]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0002943//tRNA dihydrouridine synthesis;GO:0008033//tRNA processing	--
ENSG00000105866	3.777	3.23	3.089	2.656	2.461	2.676	444	390	264	231	245	227	SP4	Sp4 transcription factor [Source:HGNC Symbol;Acc:HGNC:11209]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000105875	3.875	4.25	4.481	3.453	4.267	4.252	362	395	314	236	342	286	WDR91	WD repeat domain 91 [Source:HGNC Symbol;Acc:HGNC:24997]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031313//extrinsic component of endosome membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane	GO:0005515//protein binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity	GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045022//early endosome to late endosome transport;GO:1903362//regulation of cellular protein catabolic process	--
ENSG00000105877	0.063	0.028	0.033	0.014	0.037	0.01	18.65	8.25	7.19	3.11	9.3	2.06	DNAH11	dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097728//9+0 motile cilium;GO:0097729//9+2 motile cilium;GO:0120134//proximal portion of axoneme	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0003356//regulation of cilium beat frequency;GO:0007018//microtubule-based movement;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0007611//learning or memory;GO:0030317//flagellated sperm motility;GO:0035545//determination of left/right asymmetry in nervous system;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0060411//cardiac septum morphogenesis;GO:0120229//protein localization to motile cilium	--
ENSG00000105879	6.951	9	7.021	8.038	9.577	8.062	498	565	346	351	444	378	CBLL1	Cbl proto-oncogene like 1 [Source:HGNC Symbol;Acc:HGNC:21225]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007162//negative regulation of cell adhesion;GO:0016567//protein ubiquitination;GO:0030155//regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0045807//positive regulation of endocytosis;GO:0080009//mRNA methylation;GO:0098609//cell-cell adhesion	--
ENSG00000105880	0.18	0	0	0	0	0	4	0	0	0	0	0	DLX5	distal-less homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2918]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18489	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0008283//cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0021889//olfactory bulb interneuron differentiation;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0042472//inner ear morphogenesis;GO:0043583//ear development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060166//olfactory pit development;GO:0060322//head development;GO:0060325//face morphogenesis;GO:0060349//bone morphogenesis;GO:0071773//cellular response to BMP stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097376//interneuron axon guidance;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	Homeobox
ENSG00000105887	79.341	71.585	73.051	63.352	69.106	72.971	6224	5621	4218	3640	4555	4165	MTPN	myotrophin [Source:HGNC Symbol;Acc:HGNC:15667]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008290//F-actin capping protein complex;GO:0030424//axon;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	GO:0006417//regulation of translation;GO:0006584//catecholamine metabolic process;GO:0008361//regulation of cell size;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0016202//regulation of striated muscle tissue development;GO:0021707//cerebellar granule cell differentiation;GO:0030182//neuron differentiation;GO:0030307//positive regulation of cell growth;GO:0043403//skeletal muscle tissue regeneration;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051146//striated muscle cell differentiation;GO:0051247//positive regulation of protein metabolic process;GO:0071260//cellular response to mechanical stimulus;GO:2000812//regulation of barbed-end actin filament capping	--
ENSG00000105889	1.414	1.878	2.121	0.981	0.798	1.206	35	47	34	19	17	22	STEAP1B	STEAP family member 1B [Source:HGNC Symbol;Acc:HGNC:41907]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14737	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000105894	63.768	63.054	63.548	51.838	57.917	65.775	1968	1955	1449	1187	1511	1480	PTN	pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0004864//protein phosphatase inhibitor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0019901//protein kinase binding;GO:0035374//chondroitin sulfate binding	GO:0001503//ossification;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007165//signal transduction;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007399//nervous system development;GO:0007406//negative regulation of neuroblast proliferation;GO:0007612//learning;GO:0007613//memory;GO:0008284//positive regulation of cell population proliferation;GO:0010594//regulation of endothelial cell migration;GO:0010976//positive regulation of neuron projection development;GO:0010996//response to auditory stimulus;GO:0030282//bone mineralization;GO:0030501//positive regulation of bone mineralization;GO:0031104//dendrite regeneration;GO:0031641//regulation of myelination;GO:0042246//tissue regeneration;GO:0043086//negative regulation of catalytic activity;GO:0043113//receptor clustering;GO:0043932//ossification involved in bone remodeling;GO:0044849//estrous cycle;GO:0045597//positive regulation of cell differentiation;GO:0045778//positive regulation of ossification;GO:0046697//decidualization;GO:0048167//regulation of synaptic plasticity;GO:0048477//oogenesis;GO:0048680//positive regulation of axon regeneration;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050896//response to stimulus;GO:0051781//positive regulation of cell division;GO:0140059//dendrite arborization;GO:1900006//positive regulation of dendrite development;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1903706//regulation of hemopoiesis;GO:2000036//regulation of stem cell population maintenance;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000738//positive regulation of stem cell differentiation	--
ENSG00000105926	2.856	1.672	1.138	2.076	1.903	1.72	236	139	69	92	98	103	PALS2	"protein associated with LIN7 2, MAGUK family member [Source:HGNC Symbol;Acc:HGNC:18167]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0065003//protein-containing complex assembly	--
ENSG00000105928	7.466	7.743	6.367	6.799	6.402	7.226	346	349	220	235	250	237	GSDME	gasdermin E [Source:HGNC Symbol;Acc:HGNC:2810]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:1901612//cardiolipin binding"	GO:0007605//sensory perception of sound;GO:0008219//cell death;GO:0008285//negative regulation of cell population proliferation;GO:0012501//programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0060113//inner ear receptor cell differentiation;GO:0070265//necrotic cell death;GO:0070269//pyroptosis;GO:0071356//cellular response to tumor necrosis factor;GO:0098586//cellular response to virus;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000105929	1.089	1.166	1.45	2.334	1.661	2.57	64	56	46	100	80	113	ATP6V0A4	ATPase H+ transporting V0 subunit a4 [Source:HGNC Symbol;Acc:HGNC:866]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154	"GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030670//phagocytic vesicle membrane;GO:0031526//brush border membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0045177//apical part of cell;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0001503//ossification;GO:0006811//ion transport;GO:0006885//regulation of pH;GO:0007035//vacuolar acidification;GO:0007605//sensory perception of sound;GO:0051452//intracellular pH reduction;GO:0097254//renal tubular secretion;GO:1902600//proton transmembrane transport	--
ENSG00000105939	7.148	5.638	5.191	5.139	6.409	5.863	973	801	548	547	729	605	ZC3HAV1	"zinc finger CCCH-type containing, antiviral 1 [Source:HGNC Symbol;Acc:HGNC:23721]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0009615//response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0061014//positive regulation of mRNA catabolic process;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000105948	3.183	2.424	2.366	2.152	2.27	2.489	251	217	153	123	138	145	TTC26	tetratricopeptide repeat domain 26 [Source:HGNC Symbol;Acc:HGNC:21882]	-	-	-	-	GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0120170//intraciliary transport particle B binding	GO:0007224//smoothened signaling pathway;GO:0007286//spermatid development;GO:0015031//protein transport;GO:0035082//axoneme assembly;GO:0035720//intraciliary anterograde transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1905198//manchette assembly	--
ENSG00000105953	79.405	83.145	93.078	97.736	92.716	85.013	6475	6828	5611	5835	6363	5175	OGDH	oxoglutarate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8124]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00164;K00164;K00164	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane;GO:0045252//oxoglutarate dehydrogenase complex	"GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0030976//thiamine pyrophosphate binding;GO:0031072//heat shock protein binding;GO:0034602//oxoglutarate dehydrogenase (NAD+) activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding"	GO:0006091//generation of precursor metabolites and energy;GO:0006096//glycolytic process;GO:0006099//tricarboxylic acid cycle;GO:0006103//2-oxoglutarate metabolic process;GO:0006104//succinyl-CoA metabolic process;GO:0006734//NADH metabolic process;GO:0021695//cerebellar cortex development;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0021794//thalamus development;GO:0021860//pyramidal neuron development;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0061034//olfactory bulb mitral cell layer development;GO:0106077//histone succinylation	--
ENSG00000105954	0.081	0.161	0	0	0.048	0	2	4	0	0	1	0	NPVF	neuropeptide VF precursor [Source:HGNC Symbol;Acc:HGNC:13782]	-	-	-	-	GO:0005576//extracellular region	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007218//neuropeptide signaling pathway;GO:0032277//negative regulation of gonadotropin secretion	--
ENSG00000105963	0.871	0.318	0.422	0.994	0.789	0.724	21.05	8.25	9	20.92	26	18	ADAP1	ArfGAP with dual PH domains 1 [Source:HGNC Symbol;Acc:HGNC:16486]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0046872//metal ion binding;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0007166//cell surface receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000105967	0.46	0.354	0.417	0.594	0.288	0.493	44	34	34	37	24	37	TFEC	transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0034605//cellular response to heat;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000105968	42.279	36.351	32.568	28.717	32.725	33.189	2515	2204	1522	1278	1612	1440	H2AZ2	H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0008150//biological_process	--
ENSG00000105971	6.101	4.686	5.673	6.525	6.471	5.791	324	272	215	249	264	250	CAV2	caveolin 2 [Source:HGNC Symbol;Acc:HGNC:1528]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Neurodegenerative disease;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Infectious disease: bacterial	ko05020//Prion disease;ko04144//Endocytosis;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05418//Fluid shear stress and atherosclerosis;ko05100//Bacterial invasion of epithelial cells	K12958;K12958;K12958;K12958;K12958;K12958	GO:0000139//Golgi membrane;GO:0002080//acrosomal membrane;GO:0002095//caveolar macromolecular signaling complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0060090//molecular adaptor activity;GO:0097110//scaffold protein binding	GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006906//vesicle fusion;GO:0007005//mitochondrion organization;GO:0007029//endoplasmic reticulum organization;GO:0007088//regulation of mitotic nuclear division;GO:0008285//negative regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0016050//vesicle organization;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019076//viral release from host cell;GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0043547//positive regulation of GTPase activity;GO:0044794//positive regulation by host of viral process;GO:0048278//vesicle docking;GO:0048741//skeletal muscle fiber development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0070836//caveola assembly;GO:0071711//basement membrane organization	--
ENSG00000105974	2.993	2.233	2.857	2.212	1.643	2.492	127	117	104	80	70	78	CAV1	caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial	ko05020//Prion disease;ko04144//Endocytosis;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05418//Fluid shear stress and atherosclerosis;ko05416//Viral myocarditis;ko05100//Bacterial invasion of epithelial cells	K06278;K06278;K06278;K06278;K06278;K06278;K06278	GO:0000139//Golgi membrane;GO:0002080//acrosomal membrane;GO:0002095//caveolar macromolecular signaling complex;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005113//patched binding;GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0016504//peptidase activator activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0050998//nitric-oxide synthase binding;GO:0051117//ATPase binding;GO:0060090//molecular adaptor activity;GO:0070320//inward rectifier potassium channel inhibitor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002026//regulation of the force of heart contraction;GO:0002931//response to ischemia;GO:0003057//regulation of the force of heart contraction by chemical signal;GO:0006641//triglyceride metabolic process;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006940//regulation of smooth muscle contraction;GO:0007519//skeletal muscle tissue development;GO:0007595//lactation;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0009617//response to bacterium;GO:0009968//negative regulation of signal transduction;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010608//posttranscriptional regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010875//positive regulation of cholesterol efflux;GO:0010952//positive regulation of peptidase activity;GO:0015031//protein transport;GO:0016050//vesicle organization;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019217//regulation of fatty acid metabolic process;GO:0019915//lipid storage;GO:0030154//cell differentiation;GO:0030193//regulation of blood coagulation;GO:0030301//cholesterol transport;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030879//mammary gland development;GO:0031295//T cell costimulation;GO:0031397//negative regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0031623//receptor internalization;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032507//maintenance of protein location in cell;GO:0032570//response to progesterone;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033484//nitric oxide homeostasis;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0038016//insulin receptor internalization;GO:0042310//vasoconstriction;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042632//cholesterol homeostasis;GO:0043085//positive regulation of catalytic activity;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0043627//response to estrogen;GO:0044860//protein localization to plasma membrane raft;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045907//positive regulation of vasoconstriction;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0048550//negative regulation of pinocytosis;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051592//response to calcium ion;GO:0051899//membrane depolarization;GO:0052547//regulation of peptidase activity;GO:0055074//calcium ion homeostasis;GO:0060056//mammary gland involution;GO:0060355//positive regulation of cell adhesion molecule production;GO:0060546//negative regulation of necroptotic process;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0070836//caveola assembly;GO:0071360//cellular response to exogenous dsRNA;GO:0071375//cellular response to peptide hormone stimulus;GO:0071455//cellular response to hyperoxia;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071711//basement membrane organization;GO:0072584//caveolin-mediated endocytosis;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086098//angiotensin-activated signaling pathway involved in heart process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0098903//regulation of membrane repolarization during action potential;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900027//regulation of ruffle assembly;GO:1900085//negative regulation of peptidyl-tyrosine autophosphorylation;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903361//protein localization to basolateral plasma membrane;GO:1903598//positive regulation of gap junction assembly;GO:1903609//negative regulation of inward rectifier potassium channel activity;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:2000535//regulation of entry of bacterium into host cell;GO:2000811//negative regulation of anoikis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000105976	65.445	58.357	62.492	57.527	61.255	73.691	8257	7085	5869	5731	6764	6586	MET	"MET proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7029]"	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Cancer: overview;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Development and regeneration;Cancer: overview;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cellular community - eukaryotes;Infectious disease: bacterial;Infectious disease: parasitic	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05226//Gastric cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05144//Malaria	K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099;K05099	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005008//hepatocyte growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017154//semaphorin receptor activity;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding	GO:0001886//endothelial cell morphogenesis;GO:0001889//liver development;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0010507//negative regulation of autophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030182//neuron differentiation;GO:0031016//pancreas development;GO:0031116//positive regulation of microtubule polymerization;GO:0033674//positive regulation of kinase activity;GO:0035024//negative regulation of Rho protein signal transduction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050896//response to stimulus;GO:0050918//positive chemotaxis;GO:0051497//negative regulation of stress fiber assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0061436//establishment of skin barrier;GO:0070495//negative regulation of thrombin-activated receptor signaling pathway;GO:0071526//semaphorin-plexin signaling pathway;GO:1901299//negative regulation of hydrogen peroxide-mediated programmed cell death;GO:1905098//negative regulation of guanyl-nucleotide exchange factor activity;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000105982	0.87	0.378	0.72	0.634	0.596	0.53	26	14	10	13	18	15	RNF32	ring finger protein 32 [Source:HGNC Symbol;Acc:HGNC:17118]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016235//aggresome;GO:0016604//nuclear body	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000105983	14.452	14.901	15.557	14.213	14.417	16.464	1094	1112	852	721	851	796	LMBR1	limb development membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:13243]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0042733//embryonic digit morphogenesis	--
ENSG00000105989	0	0	0	0.074	0.032	0	0	0	0	2	1	0	WNT2	Wnt family member 2 [Source:HGNC Symbol;Acc:HGNC:12780]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031232//extrinsic component of external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:1990909//Wnt signalosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002088//lens development in camera-type eye;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0022008//neurogenesis;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0033278//cell proliferation in midbrain;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0050769//positive regulation of neurogenesis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060492//lung induction;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0060716//labyrinthine layer blood vessel development;GO:0061072//iris morphogenesis;GO:0061180//mammary gland epithelium development;GO:0071300//cellular response to retinoic acid;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	--
ENSG00000105991	0	0	0	0	0	0	0	0	0	0	0	0	HOXA1	homeobox A1 [Source:HGNC Symbol;Acc:HGNC:5099]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09301	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000105993	68.444	64.027	63.9	60.236	64.456	61.889	2897	2766	2020	1928	2251	1882	DNAJB6	DnaJ heat shock protein family (Hsp40) member B6 [Source:HGNC Symbol;Acc:HGNC:14888]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030018//Z disc;GO:0048471//perinuclear region of cytoplasm	GO:0001671//ATPase activator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	"GO:0006457//protein folding;GO:0030036//actin cytoskeleton organization;GO:0030198//extracellular matrix organization;GO:0032880//regulation of protein localization;GO:0034504//protein localization to nucleus;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045109//intermediate filament organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060710//chorio-allantoic fusion;GO:0060715//syncytiotrophoblast cell differentiation involved in labyrinthine layer development;GO:0060717//chorion development;GO:0061077//chaperone-mediated protein folding;GO:0090084//negative regulation of inclusion body assembly;GO:1900034//regulation of cellular response to heat"	--
ENSG00000105996	0	0	0	0	0	0	0	0	0	0	0	0	HOXA2	homeobox A2 [Source:HGNC Symbol;Acc:HGNC:5103]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001709//cell fate determination;GO:0002076//osteoblast development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007379//segment specification;GO:0007389//pattern specification process;GO:0008045//motor neuron axon guidance;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0021568//rhombomere 2 development;GO:0021569//rhombomere 3 development;GO:0021658//rhombomere 3 morphogenesis;GO:0035284//brain segmentation;GO:0042474//middle ear morphogenesis;GO:0045165//cell fate commitment;GO:0045665//negative regulation of neuron differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048703//embryonic viscerocranium morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0060037//pharyngeal system development;GO:0061061//muscle structure development;GO:0071300//cellular response to retinoic acid"	Homeobox
ENSG00000105997	0	0	0	0	0	0	0	0	0	0	0	0	HOXA3	homeobox A3 [Source:HGNC Symbol;Acc:HGNC:5104]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0071837//HMG box domain binding"	"GO:0001525//angiogenesis;GO:0001974//blood vessel remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0010159//specification of animal organ position;GO:0010467//gene expression;GO:0021615//glossopharyngeal nerve morphogenesis;GO:0030878//thyroid gland development;GO:0048538//thymus development;GO:0048645//animal organ formation;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0051216//cartilage development;GO:0060017//parathyroid gland development"	Homeobox
ENSG00000106003	1.395	1.212	1.094	1.366	1.319	1.126	62	54	39	49	55	36	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560]	Human Diseases;Environmental Information Processing;Metabolism	Infectious disease: viral;Signal transduction;Glycan biosynthesis and metabolism	ko05165//Human papillomavirus infection;ko04330//Notch signaling pathway;ko00514//Other types of O-glycan biosynthesis	K05948;K05948;K05948	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:1903561//extracellular vesicle	GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding	GO:0001541//ovarian follicle development;GO:0001756//somitogenesis;GO:0002315//marginal zone B cell differentiation;GO:0007386//compartment pattern specification;GO:0007389//pattern specification process;GO:0008593//regulation of Notch signaling pathway;GO:0009887//animal organ morphogenesis;GO:0014807//regulation of somitogenesis;GO:0030217//T cell differentiation;GO:0032092//positive regulation of protein binding;GO:0045747//positive regulation of Notch signaling pathway;GO:0051446//positive regulation of meiotic cell cycle;GO:1902367//negative regulation of Notch signaling pathway involved in somitogenesis	--
ENSG00000106004	0	0	0	0	0	0	0	0	0	0	0	0	HOXA5	homeobox A5 [Source:HGNC Symbol;Acc:HGNC:5106]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0002009//morphogenesis of an epithelium;GO:0003016//respiratory system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030324//lung development;GO:0030878//thyroid gland development;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0035264//multicellular organism growth;GO:0043065//positive regulation of apoptotic process;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0060435//bronchiole development;GO:0060439//trachea morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060480//lung goblet cell differentiation;GO:0060481//lobar bronchus epithelium development;GO:0060484//lung-associated mesenchyme development;GO:0060535//trachea cartilage morphogenesis;GO:0060536//cartilage morphogenesis;GO:0060574//intestinal epithelial cell maturation;GO:0060638//mesenchymal-epithelial cell signaling;GO:0060644//mammary gland epithelial cell differentiation;GO:0060749//mammary gland alveolus development;GO:0060764//cell-cell signaling involved in mammary gland development"	Homeobox
ENSG00000106006	0	0	0	0	0	0	0	0	0	0	0	0	HOXA6	homeobox A6 [Source:HGNC Symbol;Acc:HGNC:5107]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000106009	12.803	14.28	15.713	16.816	16.773	15.713	738	796	646	718	793	659	BRAT1	BRCA1 associated ATM activator 1 [Source:HGNC Symbol;Acc:HGNC:21701]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006006//glucose metabolic process;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0010212//response to ionizing radiation;GO:0016477//cell migration;GO:0030307//positive regulation of cell growth;GO:0051646//mitochondrion localization	--
ENSG00000106012	11.304	11.348	10.851	8.754	8.826	9.871	1126	1148	833	672	834	760	IQCE	IQ motif containing E [Source:HGNC Symbol;Acc:HGNC:29171]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K24677	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0035108//limb morphogenesis	--
ENSG00000106013	0	0	0.099	0	0	0	0	0	2	0	0	0	ANKRD7	ankyrin repeat domain 7 [Source:HGNC Symbol;Acc:HGNC:18588]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005813//centrosome	GO:0005515//protein binding	-	--
ENSG00000106018	0.151	0.224	0.42	0.861	0.81	0.818	11	18	14	51	47	36	VIPR2	vasoactive intestinal peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:12695]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway	K04590;K04590	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007267//cell-cell signaling;GO:0048662//negative regulation of smooth muscle cell proliferation	--
ENSG00000106025	9.015	6.72	7.277	7.935	6.429	9.001	370	299	236	223	220	305	TSPAN12	tetraspanin 12 [Source:HGNC Symbol;Acc:HGNC:21641]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0010842//retina layer formation;GO:0045765//regulation of angiogenesis;GO:1900746//regulation of vascular endothelial growth factor signaling pathway	--
ENSG00000106028	49.868	46.341	42.47	42.91	37.328	46.815	688	641	432	441	433	470	SSBP1	single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03440//Homologous recombination;ko03030//DNA replication;ko03430//Mismatch repair	K03111;K03111;K03111	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0009295//nucleoid;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006260//DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0051096//positive regulation of helicase activity;GO:0051289//protein homotetramerization;GO:0070584//mitochondrion morphogenesis;GO:0090297//positive regulation of mitochondrial DNA replication;GO:1905776//positive regulation of DNA helicase activity	--
ENSG00000106031	0.01	0	0	0	0.046	0	1	0	0	0	4	0	HOXA13	homeobox A13 [Source:HGNC Symbol;Acc:HGNC:5102]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0045111//intermediate filament cytoskeleton	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001570//vasculogenesis;GO:0001886//endothelial cell morphogenesis;GO:0001894//tissue homeostasis;GO:0003281//ventricular septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0030510//regulation of BMP signaling pathway;GO:0030539//male genitalia development;GO:0030850//prostate gland development;GO:0033574//response to testosterone;GO:0035115//embryonic forelimb morphogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048619//embryonic hindgut morphogenesis;GO:0048839//inner ear development;GO:0048844//artery morphogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060847//endothelial cell fate specification;GO:2001055//positive regulation of mesenchymal cell apoptotic process"	Homeobox
ENSG00000106034	0.4	0.8	0.207	0.664	0.456	0.255	34	34	14	19	36	18	CPED1	cadherin like and PC-esterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26159]	-	-	-	-	GO:0005783//endoplasmic reticulum	-	-	--
ENSG00000106038	0	0	0	0	0	0	0	0	0	0	0	0	EVX1	even-skipped homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3506]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030424//axon;GO:0044297//cell body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009792//embryo development ending in birth or egg hatching;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097377//spinal cord interneuron axon guidance;GO:1904936//interneuron migration"	Homeobox
ENSG00000106049	73.599	74.246	77.651	65.577	66.773	74.411	2864	2907	2234	1891	2196	2109	HIBADH	3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K00020;K00020	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0005515//protein binding;GO:0008442//3-hydroxyisobutyrate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0050661//NADP binding;GO:0051287//NAD binding"	GO:0006574//valine catabolic process;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000106052	144.245	129.788	120.094	73.138	87.882	88.395	7970	7293.03	4913	3006.01	4130	3579	TAX1BP1	Tax1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11575]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K21347	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0043066//negative regulation of apoptotic process	Others
ENSG00000106066	53.094	61.559	54.767	58.499	55.655	47.996	2075	2383	1570	1669	1874	1373	CPVL	carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399]	-	-	-	-	GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000106069	2.952	2.955	2.895	4.861	4.39	6.064	189.62	183.9	102	161.48	185	242	CHN2	chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0045202//synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000106070	17.875	18.652	15.543	17.232	18.226	17.975	1563	1654	1095	1080	1383	1204	GRB10	growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20064	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0010467//gene expression;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032868//response to insulin;GO:0042326//negative regulation of phosphorylation;GO:0042327//positive regulation of phosphorylation;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1904738//vascular associated smooth muscle cell migration	--
ENSG00000106077	11.015	10.356	10.887	11.719	10.886	9.652	297	305	231	249	252	200	ABHD11	abhydrolase domain containing 11 [Source:HGNC Symbol;Acc:HGNC:16407]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0008150//biological_process	--
ENSG00000106078	1.157	1.483	0.812	0.569	0.692	0.897	128	134	62	46	61	44	COBL	cordon-bleu WH2 repeat protein [Source:HGNC Symbol;Acc:HGNC:22199]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone;GO:0048471//perinuclear region of cytoplasm;GO:1990357//terminal web	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding	GO:0000578//embryonic axis specification;GO:0001757//somite specification;GO:0001843//neural tube closure;GO:0001889//liver development;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030903//notochord development;GO:0033504//floor plate development;GO:0048565//digestive tract development;GO:0048669//collateral sprouting in absence of injury;GO:0051639//actin filament network formation;GO:1900006//positive regulation of dendrite development;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000106080	5.93	5.332	4.801	3.256	3.703	4.166	578	504.17	340	249	323	313	FKBP14	FKBP prolyl isomerase 14 [Source:HGNC Symbol;Acc:HGNC:18625]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0000413//protein peptidyl-prolyl isomerization	--
ENSG00000106086	5.789	4.476	4.902	3.716	4.364	5.101	732	635	436	361	477	467	PLEKHA8	pleckstrin homology domain containing A8 [Source:HGNC Symbol;Acc:HGNC:30037]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane	GO:0008289//lipid binding;GO:0017089//glycolipid transfer activity;GO:0051861//glycolipid binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0097001//ceramide binding;GO:0120013//lipid transfer activity;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0006869//lipid transport;GO:0015031//protein transport;GO:0035621//ER to Golgi ceramide transport;GO:0035627//ceramide transport;GO:0046836//glycolipid transport;GO:0120009//intermembrane lipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000106089	1.8	1.485	1.57	0.609	0.947	0.937	41	33	29	19	26	29	STX1A	syntaxin 1A [Source:HGNC Symbol;Acc:HGNC:11433]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Nervous system;Substance dependence;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease;ko04911//Insulin secretion;ko04721//Synaptic vesicle cycle;ko05031//Amphetamine addiction;ko04130//SNARE interactions in vesicular transport	K04560;K04560;K04560;K04560;K04560;K04560	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0008076//voltage-gated potassium channel complex;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030285//integral component of synaptic vesicle membrane;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0042641//actomyosin;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043229//intracellular organelle;GO:0045202//synapse;GO:0048787//presynaptic active zone membrane;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0019855//calcium channel inhibitor activity;GO:0019869//chloride channel inhibitor activity;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0032028//myosin head/neck binding;GO:0042802//identical protein binding;GO:0043008//ATP-dependent protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding;GO:0048306//calcium-dependent protein binding	GO:0001956//positive regulation of neurotransmitter secretion;GO:0006836//neurotransmitter transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0009629//response to gravity;GO:0010701//positive regulation of norepinephrine secretion;GO:0010807//regulation of synaptic vesicle priming;GO:0016079//synaptic vesicle exocytosis;GO:0016081//synaptic vesicle docking;GO:0016192//vesicle-mediated transport;GO:0016925//protein sumoylation;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0032940//secretion by cell;GO:0033605//positive regulation of catecholamine secretion;GO:0035493//SNARE complex assembly;GO:0045055//regulated exocytosis;GO:0045921//positive regulation of exocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0046879//hormone secretion;GO:0048278//vesicle docking;GO:0048488//synaptic vesicle endocytosis;GO:0050796//regulation of insulin secretion;GO:0072657//protein localization to membrane;GO:0098815//modulation of excitatory postsynaptic potential;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000106100	1.491	1.72	2.095	2.426	1.647	1.785	114	144	97	102	130	104	NOD1	nucleotide binding oligomerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16390]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial	ko05132//Salmonella infection;ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko05133//Pertussis;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K08727;K08727;K08727;K08727;K08727	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0045335//phagocytic vesicle;GO:0046658//anchored component of plasma membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0038187//pattern recognition receptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042834//peptidoglycan binding;GO:0044877//protein-containing complex binding;GO:0050700//CARD domain binding	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0009595//detection of biotic stimulus;GO:0010942//positive regulation of cell death;GO:0016045//detection of bacterium;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050830//defense response to Gram-positive bacterium;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071225//cellular response to muramyl dipeptide;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904417//positive regulation of xenophagy	--
ENSG00000106105	40.986	37.908	32.611	30.611	31.585	52.68	1990	1799	1155	1070	1253	1843	GARS1	glycyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:4162]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01880	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0030424//axon;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004081//bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004820//glycine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006426//glycyl-tRNA aminoacylation;GO:0015966//diadenosine tetraphosphate biosynthetic process;GO:0044238//primary metabolic process;GO:0070150//mitochondrial glycyl-tRNA aminoacylation	--
ENSG00000106113	0.016	0.098	0.041	0.087	0.136	0	1	6	1	3	7	0	CRHR2	corticotropin releasing hormone receptor 2 [Source:HGNC Symbol;Acc:HGNC:2358]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome	K04579;K04579;K04579	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043679//axon terminus	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0015056//corticotrophin-releasing factor receptor activity;GO:0017046//peptide hormone binding;GO:0043404//corticotropin-releasing hormone receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0060291//long-term synaptic potentiation;GO:0071376//cellular response to corticotropin-releasing hormone stimulus	--
ENSG00000106123	0.565	0.751	0.632	0.911	0.946	0.837	43	51	36	56	65	47	EPHB6	EPH receptor B6 [Source:HGNC Symbol;Acc:HGNC:3396]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05114	GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005003//ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0001806//type IV hypersensitivity;GO:0002456//T cell mediated immunity;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0032092//positive regulation of protein binding;GO:0048013//ephrin receptor signaling pathway;GO:0050798//activated T cell proliferation;GO:2000525//positive regulation of T cell costimulation	--
ENSG00000106125	2.928	2.176	3.033	2.763	2.965	2.836	166	124	127	116	142	116.96	MINDY4	MINDY lysine 48 deubiquitinase 4 [Source:HGNC Symbol;Acc:HGNC:21916]	-	-	-	-	-	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000106128	0.033	0	0	0	0	0	1	0	0	0	0	0	GHRHR	growth hormone releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4266]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04935//Growth hormone synthesis, secretion and action"	K04584;K04584	GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0030141//secretory granule;GO:0042383//sarcolemma	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016520//growth hormone-releasing hormone receptor activity;GO:0017046//peptide hormone binding;GO:0019838//growth factor binding	"GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007595//lactation;GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0008340//determination of adult lifespan;GO:0019933//cAMP-mediated signaling;GO:0021984//adenohypophysis development;GO:0030104//water homeostasis;GO:0030879//mammary gland development;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0033143//regulation of intracellular steroid hormone receptor signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0042445//hormone metabolic process;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:0046887//positive regulation of hormone secretion;GO:0048469//cell maturation;GO:0048609//multicellular organismal reproductive process;GO:0051246//regulation of protein metabolic process;GO:0051384//response to glucocorticoid;GO:0060124//positive regulation of growth hormone secretion;GO:0060133//somatotropin secreting cell development;GO:0071333//cellular response to glucose stimulus"	--
ENSG00000106144	9.692	10.065	9.419	9.121	10.467	11.521	822	858	590	573	750	711	CASP2	caspase 2 [Source:HGNC Symbol;Acc:HGNC:1503]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K02186	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:1905369//endopeptidase complex	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	"GO:0001554//luteolysis;GO:0003407//neural retina development;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007420//brain development;GO:0007568//aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0016485//protein processing;GO:0035234//ectopic germ cell programmed cell death;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097194//execution phase of apoptosis;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000106153	46.336	49.77	51.272	55.205	45.036	51.711	766	827	626	676	629	622	CHCHD2	coiled-coil-helix-coiled-coil-helix domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21645]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding	GO:0007005//mitochondrion organization;GO:0034599//cellular response to oxidative stress;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1900037//regulation of cellular response to hypoxia;GO:1905448//positive regulation of mitochondrial ATP synthesis coupled electron transport	--
ENSG00000106178	0.034	0	0	0	0	0	1	0	0	0	0	0	CCL24	C-C motif chemokine ligand 24 [Source:HGNC Symbol;Acc:HGNC:10623]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21097;K21097;K21097	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031728//CCR3 chemokine receptor binding;GO:0048018//receptor ligand activity;GO:0048020//CCR chemokine receptor binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0043547//positive regulation of GTPase activity;GO:0045766//positive regulation of angiogenesis;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:2000418//positive regulation of eosinophil migration	--
ENSG00000106211	253.016	255.361	252.209	275.644	285.21	261.802	4079	4141	3004	3292	3887	3074	HSPB1	heat shock protein family B (small) member 1 [Source:HGNC Symbol;Acc:HGNC:5246]	Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: parasitic;Signal transduction	ko04010//MAPK signaling pathway;ko05146//Amoebiasis;ko04370//VEGF signaling pathway	K04455;K04455;K04455	GO:0000502//proteasome complex;GO:0001533//cornified envelope;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0043292//contractile fiber;GO:0070062//extracellular exosome;GO:1904115//axon cytoplasm	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008426//protein kinase C inhibitor activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043130//ubiquitin binding;GO:0044183//protein folding chaperone;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001895//retina homeostasis;GO:0001932//regulation of protein phosphorylation;GO:0006446//regulation of translational initiation;GO:0006469//negative regulation of protein kinase activity;GO:0006986//response to unfolded protein;GO:0009615//response to virus;GO:0010506//regulation of autophagy;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0061077//chaperone-mediated protein folding;GO:0070527//platelet aggregation;GO:0099641//anterograde axonal protein transport;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000106236	5.011	5.675	6.039	4.198	4.291	4.152	282	321	251	175	204	170	NPTX2	neuronal pentraxin 2 [Source:HGNC Symbol;Acc:HGNC:7953]	-	-	-	-	GO:0005576//extracellular region;GO:0098978//glutamatergic synapse	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0007268//chemical synaptic transmission;GO:0008306//associative learning;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000106244	57.421	57.058	60.867	60.571	53.326	55.813	1444	1447	1129	1122	1144	982	PDAP1	PDGFA associated protein 1 [Source:HGNC Symbol;Acc:HGNC:14634]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000106245	29.044	30.823	26.412	26.964	24.195	30.21	660	699.8	443	452.72	463.63	499.82	BUD31	BUD31 homolog [Source:HGNC Symbol;Acc:HGNC:29629]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12873	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071007//U2-type catalytic step 2 spliceosome	GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000825//positive regulation of androgen receptor activity"	--
ENSG00000106246	4.091	4.04	3.155	3.422	6.012	3.165	362.59	281.54	264.06	260.76	286.12	178.33	PTCD1	pentatricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:22198]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0008033//tRNA processing;GO:0042780//tRNA 3'-end processing	--
ENSG00000106258	0.612	0.376	0.482	0.276	0.534	0.252	55	34	33	19	40	17	CYP3A5	cytochrome P450 family 3 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:2638]	Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis	K17690;K17690;K17690;K17690;K17690;K17690	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity"	GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0009822//alkaloid catabolic process;GO:0042178//xenobiotic catabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0046222//aflatoxin metabolic process;GO:0070989//oxidative demethylation	--
ENSG00000106261	12.121	11.192	10.198	10.018	9.109	8.619	2364	2194	1469	1217	1501	1221	ZKSCAN1	zinc finger with KRAB and SCAN domains 1 [Source:HGNC Symbol;Acc:HGNC:13101]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000106263	57.316	53.965	52.623	53.308	54.159	45.87	3026	3009	2128	2170	2506	1862	EIF3B	eukaryotic translation initiation factor 3 subunit B [Source:HGNC Symbol;Acc:HGNC:3280]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding;GO:0060090//molecular adaptor activity	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0075522//IRES-dependent viral translational initiation;GO:0075525//viral translational termination-reinitiation	--
ENSG00000106266	10.181	9.317	10.462	13.949	12.774	10.283	811	836	721	834	926	659	SNX8	sorting nexin 8 [Source:HGNC Symbol;Acc:HGNC:14972]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030904//retromer complex;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	"GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0034498//early endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000106268	4.879	6.885	5.348	4.382	4.756	4.576	68	95	55	45	56	46	NUDT1	nudix hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:8048]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031965//nuclear membrane	"GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008413//8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity;GO:0008828//dATP pyrophosphohydrolase activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0030515//snoRNA binding;GO:0035539//8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity;GO:0046872//metal ion binding;GO:0047693//ATP diphosphatase activity;GO:0106377//2-hydroxy-ATP hydrolase activity;GO:0106378//2-hydroxy-dATP hydrolase activity"	GO:0006152//purine nucleoside catabolic process;GO:0006281//DNA repair;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0008584//male gonad development;GO:0042262//DNA protection;GO:0046686//response to cadmium ion	--
ENSG00000106278	35.68	30.195	25.889	20.396	24.917	23.769	4050	3450	2162	1694	2332	1944	PTPRZ1	protein tyrosine phosphatase receptor type Z1 [Source:HGNC Symbol;Acc:HGNC:9685]	Human Diseases	Infectious disease: bacterial	ko05120//Epithelial cell signaling in Helicobacter pylori infection	K08114	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0031226//intrinsic component of plasma membrane;GO:0045202//synapse;GO:0072534//perineuronal net	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006470//protein dephosphorylation;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0016311//dephosphorylation;GO:0031641//regulation of myelination;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0048709//oligodendrocyte differentiation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0070445//regulation of oligodendrocyte progenitor proliferation	--
ENSG00000106290	24.212	25.085	25.88	23.3	24.882	27.796	1224.28	1275.32	971.2	879.86	1069.66	1009.38	TAF6	TATA-box binding protein associated factor 6 [Source:HGNC Symbol;Acc:HGNC:11540]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03131	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0033276//transcription factor TFTC complex;GO:0046695//SLIK (SAGA-like) complex;GO:0071339//MLL1 complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0046982//protein heterodimerization activity	"GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000106299	15.426	12.906	13.256	12.098	11.915	14.716	1396	1174	886	811	911	969	WASL	WASP like actin nucleation promoting factor [Source:HGNC Symbol;Acc:HGNC:12735]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Infectious disease: bacterial;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko05100//Bacterial invasion of epithelial cells;ko04520//Adherens junction	K23612;K23612;K23612;K23612;K23612;K23612;K23612;K23612	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030478//actin cap;GO:0030666//endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0006900//vesicle budding from membrane;GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0008154//actin polymerization or depolymerization;GO:0009617//response to bacterium;GO:0016050//vesicle organization;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030048//actin filament-based movement;GO:0030050//vesicle transport along actin filament;GO:0031503//protein-containing complex localization;GO:0032880//regulation of protein localization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051491//positive regulation of filopodium assembly;GO:0051653//spindle localization;GO:0060997//dendritic spine morphogenesis;GO:0065003//protein-containing complex assembly;GO:1903526//negative regulation of membrane tubulation;GO:2000370//positive regulation of clathrin-dependent endocytosis;GO:2000402//negative regulation of lymphocyte migration;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000106302	0	0	0	0	0	0	0	0	0	0	0	0	HYAL4	hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01197;K01197;K01197	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	"GO:0003824//catalytic activity;GO:0004415//hyalurononglucosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008152//metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0030214//hyaluronan catabolic process	--
ENSG00000106304	0	0	0	0	0	0	0	0	0	0	0	0	SPAM1	sperm adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:11217]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01197;K01197;K01197	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle	"GO:0003824//catalytic activity;GO:0004415//hyalurononglucosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0008152//metabolic process;GO:0030214//hyaluronan catabolic process	--
ENSG00000106305	12.182	14.543	15.315	17.104	16.598	17.078	299.78	359.46	278.83	311.64	345.58	303.58	AIMP2	aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0006412//translation;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0031398//positive regulation of protein ubiquitination;GO:0060510//type II pneumocyte differentiation;GO:0065003//protein-containing complex assembly;GO:1901216//positive regulation of neuron death;GO:1903632//positive regulation of aminoacyl-tRNA ligase activity	--
ENSG00000106327	0.11	0.017	0.153	0.059	0.108	0.06	5	1	6	2	5	2	TFR2	transferrin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11762]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:1990712//HFE-transferrin receptor complex	GO:0004998//transferrin receptor activity;GO:0005515//protein binding;GO:0039706//co-receptor binding	GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006898//receptor-mediated endocytosis;GO:0006953//acute-phase response;GO:0010039//response to iron ion;GO:0033572//transferrin transport;GO:0045807//positive regulation of endocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055072//iron ion homeostasis;GO:0071281//cellular response to iron ion;GO:0090277//positive regulation of peptide hormone secretion;GO:0140298//endocytic iron import into cell;GO:1903319//positive regulation of protein maturation	--
ENSG00000106328	0	0	0	0	0	0	0	0	0	0	0	0	FSCN3	fascin actin-bundling protein 3 [Source:HGNC Symbol;Acc:HGNC:3961]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030426//growth cone;GO:0031253//cell projection membrane	GO:0003779//actin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007286//spermatid development;GO:0016477//cell migration;GO:0051017//actin filament bundle assembly	--
ENSG00000106330	9.145	10.025	10.465	11.014	9.704	10.311	210	234	180	188	190	172	MOSPD3	motile sperm domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25078]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0033149//FFAT motif binding	GO:0007507//heart development;GO:0061817//endoplasmic reticulum-plasma membrane tethering;GO:0090158//endoplasmic reticulum membrane organization	--
ENSG00000106331	0	0	0	0	0	0	0	0	0	0	0	0	PAX4	paired box 4 [Source:HGNC Symbol;Acc:HGNC:8618]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08032	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0009410//response to xenobiotic stimulus;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0031016//pancreas development;GO:0043066//negative regulation of apoptotic process;GO:0045595//regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048856//anatomical structure development;GO:0051591//response to cAMP;GO:0060041//retina development in camera-type eye"	PAX
ENSG00000106333	15.456	15.06	14.597	17.431	15.772	14.467	486	476	339	406	419	331	PCOLCE	procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0016504//peptidase activator activity	GO:0007275//multicellular organism development;GO:0010952//positive regulation of peptidase activity	--
ENSG00000106336	0.094	0.021	0.136	0.625	0.133	0.122	4	1	2	8	3	3	FBXO24	F-box protein 24 [Source:HGNC Symbol;Acc:HGNC:13595]	-	-	-	-	GO:0000151//ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000106341	0	0	0	0	0.032	0	0	0	0	0	1	0	PPP1R17	protein phosphatase 1 regulatory subunit 17 [Source:HGNC Symbol;Acc:HGNC:16973]	Organismal Systems	Nervous system	ko04730//Long-term depression	K08067	-	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0019212//phosphatase inhibitor activity	GO:0007417//central nervous system development;GO:0010921//regulation of phosphatase activity;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity	--
ENSG00000106344	7.313	6.338	5.511	3.834	3.48	3.931	481	391	325.05	235	332	286	RBM28	RNA binding motif protein 28 [Source:HGNC Symbol;Acc:HGNC:21863]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14573	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000106346	4.831	4.269	3.727	3.197	4.44	3.908	510	453	284	250	396	294	USP42	ubiquitin specific peptidase 42 [Source:HGNC Symbol;Acc:HGNC:20068]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007283//spermatogenesis;GO:0016579//protein deubiquitination;GO:0030154//cell differentiation;GO:0042981//regulation of apoptotic process	--
ENSG00000106348	6.299	6.277	6.488	6.313	7.461	6.987	307	299	212	236	307	257	IMPDH1	inosine monophosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6052]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes	K00088;K00088;K00088	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0003938//IMP dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006183//GTP biosynthetic process	--
ENSG00000106351	5.302	4.117	6.009	6.356	4.892	6.141	245	241	179	213	267	269	AGFG2	ArfGAP with FG repeats 2 [Source:HGNC Symbol;Acc:HGNC:5177]	-	-	-	-	GO:0016020//membrane	GO:0003674//molecular_function;GO:0005096//GTPase activator activity;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0050790//regulation of catalytic activity	--
ENSG00000106355	11.088	12.226	10.576	10.163	9.397	14.869	259	246	197	159	171	207	LSM5	"LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17162]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12624;K12624	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0120115//Lsm2-8 complex;GO:1990726//Lsm1-7-Pat1 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0008380//RNA splicing;GO:0009617//response to bacterium"	--
ENSG00000106366	44.759	39.089	29.143	13.281	17.358	14.319	2930	2572	1409	644	960	682	SERPINE1	serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583]	Cellular Processes;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes	Cell growth and death;Signal transduction;Signal transduction;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Immune system;Cell growth and death	ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04371//Apelin signaling pathway;ko04066//HIF-1 signaling pathway;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04610//Complement and coagulation cascades;ko04115//p53 signaling pathway	K03982;K03982;K03982;K03982;K03982;K03982;K03982;K03982	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0097180//serine protease inhibitor complex;GO:1904090//peptidase inhibitor complex	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001525//angiogenesis;GO:0010466//negative regulation of peptidase activity;GO:0010469//regulation of signaling receptor activity;GO:0010757//negative regulation of plasminogen activation;GO:0010951//negative regulation of endopeptidase activity;GO:0014912//negative regulation of smooth muscle cell migration;GO:0030194//positive regulation of blood coagulation;GO:0030195//negative regulation of blood coagulation;GO:0030336//negative regulation of cell migration;GO:0032757//positive regulation of interleukin-8 production;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0035491//positive regulation of leukotriene production involved in inflammatory response;GO:0042730//fibrinolysis;GO:0045766//positive regulation of angiogenesis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0051918//negative regulation of fibrinolysis;GO:0061044//negative regulation of vascular wound healing;GO:0061045//negative regulation of wound healing;GO:0071222//cellular response to lipopolysaccharide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0090399//replicative senescence;GO:0097187//dentinogenesis;GO:1901331//positive regulation of odontoblast differentiation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000106367	8.988	8.776	7.196	10.13	10.86	8.811	168	164	111	143	181	132	AP1S1	adaptor related protein complex 1 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:559]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12394;K12394	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030121//AP-1 adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0035615//clathrin adaptor activity	GO:0006886//intracellular protein transport;GO:0006898//receptor-mediated endocytosis;GO:0009615//response to virus;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060155//platelet dense granule organization;GO:0110010//basolateral protein secretion;GO:1903232//melanosome assembly	--
ENSG00000106384	0	0	0	0	0	0	0	0	0	0	0	0	MOGAT3	monoacylglycerol O-acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:23249]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K14456;K14456;K14456	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990578//perinuclear endoplasmic reticulum membrane	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process	--
ENSG00000106392	22.746	16.345	16.926	13.236	14.834	12.549	1224	971	602	520	760	592	C1GALT1	"core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24337]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00731;K00731;K00731	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016263//glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	"GO:0001525//angiogenesis;GO:0001822//kidney development;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0016267//O-glycan processing, core 1;GO:0030154//cell differentiation;GO:0060576//intestinal epithelial cell development"	--
ENSG00000106397	22.631	25.36	23.394	27.502	30.371	25.139	1280	1422	1011	1176	1351	990	PLOD3	"procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:9083]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00514//Other types of O-glycan biosynthesis	K13646;K13646;K13646	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0031418//L-ascorbic acid binding;GO:0033823//procollagen glucosyltransferase activity;GO:0046872//metal ion binding;GO:0050211//procollagen galactosyltransferase activity;GO:0051213//dioxygenase activity"	GO:0001701//in utero embryonic development;GO:0001886//endothelial cell morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0008104//protein localization;GO:0008152//metabolic process;GO:0017185//peptidyl-lysine hydroxylation;GO:0021915//neural tube development;GO:0030199//collagen fibril organization;GO:0032963//collagen metabolic process;GO:0042311//vasodilation;GO:0046947//hydroxylysine biosynthetic process;GO:0048730//epidermis morphogenesis;GO:0060425//lung morphogenesis;GO:0070831//basement membrane assembly	--
ENSG00000106399	6.901	6.377	7.907	8.279	5.994	7.815	161	170	132	132	139	143	RPA3	replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03430//Mismatch repair	K10740;K10740;K10740;K10740;K10740	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0031981//nuclear lumen;GO:0035861//site of double-strand break	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006289//nucleotide-excision repair;GO:0006298//mismatch repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007346//regulation of mitotic cell cycle;GO:0042127//regulation of cell population proliferation	--
ENSG00000106400	76.357	81.501	80.879	94.679	76.426	80.186	1153	1237	902	1059	975	881	ZNHIT1	zinc finger HIT-type containing 1 [Source:HGNC Symbol;Acc:HGNC:21688]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0046872//metal ion binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0043486//histone exchange"	--
ENSG00000106404	2.214	1.553	2.755	2.899	4.948	5.399	64	69	68	71	138	134	CLDN15	claudin 15 [Source:HGNC Symbol;Acc:HGNC:2036]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000106410	0	0	0	0	0	0	0	0	0	0	0	0	NOBOX	NOBOX oogenesis homeobox [Source:HGNC Symbol;Acc:HGNC:22448]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0048477//oogenesis	Homeobox
ENSG00000106415	3.61	2.802	3.346	3.542	3.406	4.945	355	277	243	258	283	318	GLCCI1	glucocorticoid induced 1 [Source:HGNC Symbol;Acc:HGNC:18713]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000106436	0	0	0	0	0	0	0	0	0	0	0	0	MYL10	myosin light chain 10 [Source:HGNC Symbol;Acc:HGNC:29825]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04670//Leukocyte transendothelial migration	K12756;K12756;K12756;K12756;K12756	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000106443	5.741	5.771	4.948	3.033	4.125	3.921	409	420	257	156	238	191	PHF14	PHD finger protein 14 [Source:HGNC Symbol;Acc:HGNC:22203]	-	-	-	-	GO:0005634//nucleus;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0048286//lung alveolus development;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:2000584//negative regulation of platelet-derived growth factor receptor-alpha signaling pathway;GO:2000791//negative regulation of mesenchymal cell proliferation involved in lung development	--
ENSG00000106459	3.728	3.737	3.403	4.114	4.166	4.15	232	192	152	201	192	189	NRF1	nuclear respiratory factor 1 [Source:HGNC Symbol;Acc:HGNC:7996]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05016//Huntington disease;ko04371//Apelin signaling pathway	K11831;K11831	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	Nrf1
ENSG00000106460	19.041	12.399	14.667	11.994	9.757	15.919	3205	2208	1750	1474	1701	1906	TMEM106B	transmembrane protein 106B [Source:HGNC Symbol;Acc:HGNC:22407]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0051117//ATPase binding	GO:0007040//lysosome organization;GO:0007041//lysosomal transport;GO:0007042//lysosomal lumen acidification;GO:0032418//lysosome localization;GO:0048813//dendrite morphogenesis;GO:0051345//positive regulation of hydrolase activity;GO:1900006//positive regulation of dendrite development;GO:1905146//lysosomal protein catabolic process;GO:1905671//regulation of lysosome organization	--
ENSG00000106462	4.009	3.31	3.058	2.102	2.242	2.592	217	178	126	86	106	103	EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko00310//Lysine degradation	K11430;K11430;K11430	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0035098//ESC/E(Z) complex;GO:0045120//pronucleus;GO:0045202//synapse"	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0031490//chromatin DNA binding;GO:0042054//histone methyltransferase activity;GO:0043021//ribonucleoprotein complex binding;GO:0043565//sequence-specific DNA binding;GO:0046976//histone methyltransferase activity (H3-K27 specific);GO:0070878//primary miRNA binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001932//regulation of protein phosphorylation;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0014013//regulation of gliogenesis;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0016571//histone methylation;GO:0021695//cerebellar cortex development;GO:0021766//hippocampus development;GO:0030183//B cell differentiation;GO:0031509//subtelomeric heterochromatin assembly;GO:0032259//methylation;GO:0032355//response to estradiol;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0034968//histone lysine methylation;GO:0035984//cellular response to trichostatin A;GO:0036333//hepatocyte homeostasis;GO:0042127//regulation of cell population proliferation;GO:0042752//regulation of circadian rhythm;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043547//positive regulation of GTPase activity;GO:0045605//negative regulation of epidermal cell differentiation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0048468//cell development;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0051932//synaptic transmission, GABAergic;GO:0070301//cellular response to hydrogen peroxide;GO:0070314//G1 to G0 transition;GO:0070734//histone H3-K27 methylation;GO:0071168//protein localization to chromatin;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097421//liver regeneration;GO:0098532//histone H3-K27 trimethylation;GO:1900006//positive regulation of dendrite development;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1904772//response to tetrachloromethane;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000106477	12.202	11.136	10.373	7.399	8.076	7.058	659	653	435	326	416	318	CEP41	centrosomal protein 41 [Source:HGNC Symbol;Acc:HGNC:12370]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0015031//protein transport;GO:0018095//protein polyglutamylation;GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000106479	4.699	4.371	3.848	4.983	3.885	6.672	434	437	346	357	413	375	ZNF862	zinc finger protein 862 [Source:HGNC Symbol;Acc:HGNC:34519]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0008150//biological_process"	--
ENSG00000106483	0.219	0.067	0.091	0.068	0.497	0.069	13	4	4	3	25	3	SFRP4	secreted frizzled related protein 4 [Source:HGNC Symbol;Acc:HGNC:10778]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K02185	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0009986//cell surface	GO:0005515//protein binding;GO:0017147//Wnt-protein binding	GO:0002092//positive regulation of receptor internalization;GO:0008285//negative regulation of cell population proliferation;GO:0009725//response to hormone;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045606//positive regulation of epidermal cell differentiation;GO:0048856//anatomical structure development;GO:0055062//phosphate ion homeostasis;GO:0060070//canonical Wnt signaling pathway;GO:0060349//bone morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:2000119//negative regulation of sodium-dependent phosphate transport	--
ENSG00000106484	94.77	107.442	72.642	71.678	72.698	59.524	4973	5756	2840	2805	3231	2285	MEST	mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0007498//mesoderm development;GO:0010883//regulation of lipid storage	--
ENSG00000106511	0	0	0	0	0	0	0	0	0	0	0	0	MEOX2	mesenchyme homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7014]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001525//angiogenesis;GO:0001757//somite specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007519//skeletal muscle tissue development;GO:0008015//blood circulation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060021//roof of mouth development;GO:0060173//limb development;GO:0061053//somite development;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis"	Homeobox
ENSG00000106524	14.248	11.969	13.554	10.561	12.087	12.32	671	578	482	379	482	444	ANKMY2	ankyrin repeat and MYND domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25370]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding	-	--
ENSG00000106526	2.351	1.152	1.506	0.631	0.865	1.671	58.12	38.09	20	18.06	17.09	29	ACTR3C	actin related protein 3C [Source:HGNC Symbol;Acc:HGNC:37282]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584	GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0008150//biological_process	--
ENSG00000106536	0.303	0.172	0.235	1.004	0.242	0.26	36	22	22	31	26	24	POU6F2	POU class 6 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21694]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007402//ganglion mother cell fate determination;GO:0007417//central nervous system development;GO:0007601//visual perception"	Pou
ENSG00000106537	84.299	80.027	80.542	53.515	51.246	47.546	3275	3125	2311	1540	1682	1344	TSPAN13	tetraspanin 13 [Source:HGNC Symbol;Acc:HGNC:21643]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005246//calcium channel regulator activity	GO:1903169//regulation of calcium ion transmembrane transport	--
ENSG00000106538	591.111	561.784	758.856	681.037	560.106	768.719	7856	7499	7398	6685	6291	7416	RARRES2	retinoic acid receptor responder 2 [Source:HGNC Symbol;Acc:HGNC:9868]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001523//retinoid metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0008286//insulin receptor signaling pathway;GO:0010759//positive regulation of macrophage chemotaxis;GO:0019732//antifungal humoral response;GO:0030154//cell differentiation;GO:0045087//innate immune response;GO:0045600//positive regulation of fat cell differentiation;GO:0048566//embryonic digestive tract development;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050921//positive regulation of chemotaxis;GO:0050994//regulation of lipid catabolic process;GO:0061760//antifungal innate immune response	--
ENSG00000106541	0	0	0	0	0.336	0	0	0	0	0	10	0	AGR2	"anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	GO:0002162//dystroglycan binding;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0010628//positive regulation of gene expression;GO:0010811//positive regulation of cell-substrate adhesion;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0048639//positive regulation of developmental growth;GO:0060480//lung goblet cell differentiation;GO:0060548//negative regulation of cell death;GO:0070254//mucus secretion;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:1903899//positive regulation of PERK-mediated unfolded protein response	--
ENSG00000106546	16.334	13.193	11.537	7.998	9.306	10.046	1908	1547.58	1019	697	890	874	AHR	aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Cancer: overview;Endocrine and metabolic disease;Immune system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko04934//Cushing syndrome;ko04659//Th17 cell differentiation	K09093;K09093;K09093;K09093	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0034751//aryl hydrocarbon receptor complex;GO:0034752//cytosolic aryl hydrocarbon receptor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001094//TFIID-class transcription factor complex binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0017025//TBP-class protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001568//blood vessel development;GO:0002819//regulation of adaptive immune response;GO:0002841//negative regulation of T cell mediated immune response to tumor cell;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006805//xenobiotic metabolic process;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010468//regulation of gene expression;GO:0019933//cAMP-mediated signaling;GO:0030522//intracellular receptor signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0071320//cellular response to cAMP;GO:1904322//cellular response to forskolin;GO:1904613//cellular response to 2,3,7,8-tetrachlorodibenzodioxine"	bHLH
ENSG00000106554	34.998	33.087	34.107	32.459	32.378	32.135	1163	1100	837	799	909	777	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906]	-	-	-	-	GO:0001401//SAM complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0070062//extracellular exosome;GO:0140275//MIB complex	GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0060090//molecular adaptor activity	GO:0007007//inner mitochondrial membrane organization;GO:0008053//mitochondrial fusion;GO:0042407//cristae formation	--
ENSG00000106560	0	0	0	0	0.079	0	0	0	0	0	2	0	GIMAP2	"GTPase, IMAP family member 2 [Source:HGNC Symbol;Acc:HGNC:21789]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding	-	--
ENSG00000106565	33.922	40.418	33.929	37.862	36.724	31.509	789	950	582	649	720	532	TMEM176B	transmembrane protein 176B [Source:HGNC Symbol;Acc:HGNC:29596]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding	GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:2001199//negative regulation of dendritic cell differentiation	--
ENSG00000106571	3.337	3.481	3.629	2.59	3.339	2.867	491	559	365	279	368	287	GLI3	GLI family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:4319]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04024//cAMP signaling pathway;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K06230;K06230;K06230;K06230	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0005930//axoneme;GO:0016607//nuclear speck;GO:0017053//transcription repressor complex;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:1990788//GLI-SUFU complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0035035//histone acetyltransferase binding;GO:0036033//mediator complex binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007389//pattern specification process;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007442//hindgut morphogenesis;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0016485//protein processing;GO:0021513//spinal cord dorsal/ventral patterning;GO:0021522//spinal cord motor neuron differentiation;GO:0021537//telencephalon development;GO:0021543//pallium development;GO:0021544//subpallium development;GO:0021631//optic nerve morphogenesis;GO:0021766//hippocampus development;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021801//cerebral cortex radial glia-guided migration;GO:0021819//layer formation in cerebral cortex;GO:0021861//forebrain radial glial cell differentiation;GO:0021915//neural tube development;GO:0022018//lateral ganglionic eminence cell proliferation;GO:0030318//melanocyte differentiation;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030879//mammary gland development;GO:0030900//forebrain development;GO:0032332//positive regulation of chondrocyte differentiation;GO:0033077//T cell differentiation in thymus;GO:0035108//limb morphogenesis;GO:0035295//tube development;GO:0042127//regulation of cell population proliferation;GO:0042307//positive regulation of protein import into nucleus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043585//nose morphogenesis;GO:0043586//tongue development;GO:0045060//negative thymic T cell selection;GO:0045595//regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046639//negative regulation of alpha-beta T cell differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0048566//embryonic digestive tract development;GO:0048568//embryonic organ development;GO:0048589//developmental growth;GO:0048593//camera-type eye morphogenesis;GO:0048598//embryonic morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048663//neuron fate commitment;GO:0048702//embryonic neurocranium morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048709//oligodendrocyte differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048839//inner ear development;GO:0048856//anatomical structure development;GO:0060021//roof of mouth development;GO:0060173//limb development;GO:0060364//frontal suture morphogenesis;GO:0060366//lambdoid suture morphogenesis;GO:0060367//sagittal suture morphogenesis;GO:0060594//mammary gland specification;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0060840//artery development;GO:0060873//anterior semicircular canal development;GO:0060875//lateral semicircular canal development;GO:0061005//cell differentiation involved in kidney development;GO:0070242//thymocyte apoptotic process;GO:0071625//vocalization behavior;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0120223//larynx morphogenesis;GO:1901620//regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1903010//regulation of bone development;GO:1990787//negative regulation of hh target transcription factor activity"	zf-C2H2
ENSG00000106588	24.963	29.107	24.592	28.878	24.42	25.034	742.29	767.39	540.24	564.79	586.57	533.16	PSMA2	proteasome 20S subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:9531]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02726;K02726;K02726;K02726;K02726;K02726;K02726;K02726	"GO:0000502//proteasome complex;GO:0000932//P-body;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0009615//response to virus;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000106591	19.563	18.513	20.25	19.003	19.19	22.48	369	346	285	263	306	306	MRPL32	mitochondrial ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:14035]	Genetic Information Processing	Translation	ko03010//Ribosome	K02911	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000106603	24.313	22.657	21.268	24.191	23.555	23.185	617	535	382	419	472	383	COA1	cytochrome c oxidase assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:21868]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18173	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding	GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000106605	12.779	16.425	16.742	12.111	11.721	13.653	288	370	277	201	222	222	BLVRA	biliverdin reductase A [Source:HGNC Symbol;Acc:HGNC:1062]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K00214;K00214	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004074//biliverdin reductase (NAD(P)+) activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0106276//biliberdin reductase NAD+ activity;GO:0106277//biliverdin reductase (NADP+) activity	GO:0042167//heme catabolic process	--
ENSG00000106608	17.135	15.745	17.156	18.143	20.172	20.121	1010	1042.99	742	751	987.98	882	URGCP	upregulator of cell proliferation [Source:HGNC Symbol;Acc:HGNC:30890]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005525//GTP binding	GO:0007049//cell cycle	--
ENSG00000106609	55.599	55.527	53.532	50.265	54.872	57.193	4422	4538	3298	3142	3810	3478	TMEM248	transmembrane protein 248 [Source:HGNC Symbol;Acc:HGNC:25476]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000106615	47.317	47.755	46.292	44.02	42.764	49.318	1388	1358	1014	979	1115	1054	RHEB	"Ras homolog, mTORC1 binding [Source:HGNC Symbol;Acc:HGNC:10011]"	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Environmental adaptation;Infectious disease: viral;Signal transduction;Signal transduction;Cell growth and death;Transport and catabolism;Endocrine system;Endocrine system;Signal transduction;Cancer: overview;Aging	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko05231//Choline metabolism in cancer;ko04211//Longevity regulating pathway	K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208;K07208	GO:0000139//Golgi membrane;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0016241//regulation of macroautophagy;GO:0032006//regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0051726//regulation of cell cycle;GO:0120163//negative regulation of cold-induced thermogenesis;GO:2000074//regulation of type B pancreatic cell development	--
ENSG00000106617	6.109	6.35	5.359	8.926	7.884	8.325	297	303	196	320	320	296	PRKAG2	protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386]	Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04921//Oxytocin signaling pathway;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031588//nucleotide-activated protein kinase complex	GO:0000166//nucleotide binding;GO:0004679//AMP-activated protein kinase activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0008607//phosphorylase kinase regulator activity;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0032559//adenyl ribonucleotide binding;GO:0043531//ADP binding	GO:0005977//glycogen metabolic process;GO:0006110//regulation of glycolytic process;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0016126//sterol biosynthetic process;GO:0016310//phosphorylation;GO:0019217//regulation of fatty acid metabolic process;GO:0031669//cellular response to nutrient levels;GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0045860//positive regulation of protein kinase activity;GO:0046320//regulation of fatty acid oxidation;GO:0046324//regulation of glucose import;GO:0050790//regulation of catalytic activity;GO:0071900//regulation of protein serine/threonine kinase activity;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000106624	75.45	83.986	52.04	77.789	89.317	79.652	6389	7095	3226	4809	6293	4810	AEBP1	AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005201//extracellular matrix structural constituent;GO:0005516//calmodulin binding;GO:0005518//collagen binding;GO:0008270//zinc ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:1904026//regulation of collagen fibril organization"	--
ENSG00000106628	56.532	61.619	59.56	67.124	60.84	61.519	1903	2015	1472	1673	1730	1490	POLD2	"DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K02328;K02328;K02328;K02328;K02328	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016035//zeta DNA polymerase complex;GO:0042575//DNA polymerase complex;GO:0043625//delta DNA polymerase complex	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0034645//cellular macromolecule biosynthetic process;GO:0042276//error-prone translesion synthesis;GO:0071897//DNA biosynthetic process	--
ENSG00000106631	0.903	2.029	0.101	0.464	0.559	0.356	11	26	1	4	6	4	MYL7	myosin light chain 7 [Source:HGNC Symbol;Acc:HGNC:21719]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04670//Leukocyte transendothelial migration	K12754;K12754;K12754;K12754;K12754	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0031672//A band;GO:0043197//dendritic spine	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0048738//cardiac muscle tissue development;GO:0060047//heart contraction	--
ENSG00000106633	0.331	0.803	0.647	0.397	0.696	1.162	9	22	13	8	16	23	GCK	glucokinase [Source:HGNC Symbol;Acc:HGNC:4195]	Metabolism;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Endocrine system;Global and overview maps;Endocrine system;Endocrine system;Endocrine system;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Biosynthesis of other secondary metabolites	"ko01100//Metabolic pathways;ko04910//Insulin signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko04911//Insulin secretion;ko04917//Prolactin signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko04930//Type II diabetes mellitus;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism;ko04950//Maturity onset diabetes of the young;ko00524//Neomycin, kanamycin and gentamicin biosynthesis"	K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407;K12407	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004340//glucokinase activity;GO:0004396//hexokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008865//fructokinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019158//mannokinase activity"	GO:0001678//cellular glucose homeostasis;GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006110//regulation of glycolytic process;GO:0006739//NADP metabolic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0032869//cellular response to insulin stimulus;GO:0042593//glucose homeostasis;GO:0043266//regulation of potassium ion transport;GO:0044320//cellular response to leptin stimulus;GO:0045721//negative regulation of gluconeogenesis;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046835//carbohydrate phosphorylation;GO:0050796//regulation of insulin secretion;GO:0051156//glucose 6-phosphate metabolic process;GO:0051594//detection of glucose;GO:0061621//canonical glycolysis;GO:0070509//calcium ion import	--
ENSG00000106635	15.378	17.977	20.243	19.125	16.643	22.288	498	567	480	446	453	517	BCL7B	BAF chromatin remodeling complex subunit BCL7B [Source:HGNC Symbol;Acc:HGNC:1005]	-	-	-	-	GO:0000785//chromatin;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	GO:0003779//actin binding;GO:0005515//protein binding	GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030154//cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair	--
ENSG00000106636	29.364	27.436	31.55	33.75	30.141	30.194	1644	1558	1295	1394	1382	1254	YKT6	YKT6 v-SNARE homolog [Source:HGNC Symbol;Acc:HGNC:16959]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08516	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043025//neuronal cell body;GO:0097440//apical dendrite;GO:0097441//basal dendrite;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0045296//cadherin binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006903//vesicle targeting;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0061025//membrane fusion"	--
ENSG00000106638	20.793	24.851	28.486	25.911	23.103	18.839	845	961	646	729	745	495	TBL2	transducin beta like 2 [Source:HGNC Symbol;Acc:HGNC:11586]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031369//translation initiation factor binding;GO:0051219//phosphoprotein binding	GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042149//cellular response to glucose starvation;GO:0071456//cellular response to hypoxia	--
ENSG00000106648	0	0	0	0	0	0	0	0	0	0	0	0	GALNTL5	polypeptide N-acetylgalactosaminyltransferase like 5 [Source:HGNC Symbol;Acc:HGNC:21725]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane	GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation	--
ENSG00000106665	12.294	12.07	13.126	13.688	12.387	11.849	1404	1366	1106	1157	1198	988	CLIP2	CAP-Gly domain containing linker protein 2 [Source:HGNC Symbol;Acc:HGNC:2586]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end	GO:0008017//microtubule binding;GO:0051010//microtubule plus-end binding	GO:0031122//cytoplasmic microtubule organization	--
ENSG00000106682	117.157	117.431	120.896	129.741	118.297	128.714	5978	6034	4537	4899	5110	4817	EIF4H	eukaryotic translation initiation factor 4H [Source:HGNC Symbol;Acc:HGNC:12741]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0048471//perinuclear region of cytoplasm	"GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0033592//RNA strand annealing activity;GO:0034057//RNA strand-exchange activity;GO:0043024//ribosomal small subunit binding;GO:0045296//cadherin binding"	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0019953//sexual reproduction;GO:0048589//developmental growth;GO:0097010//eukaryotic translation initiation factor 4F complex assembly	--
ENSG00000106683	20.86	19.436	18.203	19.38	20.873	19.196	1376	1305	911	999	1227	951	LIMK1	LIM domain kinase 1 [Source:HGNC Symbol;Acc:HGNC:6613]	Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cell motility;Infectious disease: viral;Infectious disease: bacterial;Development and regeneration;Immune system	ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis	K05743;K05743;K05743;K05743;K05743	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0007399//nervous system development;GO:0016310//phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045773//positive regulation of axon extension;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051496//positive regulation of stress fiber assembly	--
ENSG00000106686	0.233	0.149	0.24	0.132	0.165	0.277	14	6	11	5	10	9	SPATA6L	spermatogenesis associated 6 like [Source:HGNC Symbol;Acc:HGNC:25472]	-	-	-	-	GO:0097224//sperm connecting piece	GO:0032027//myosin light chain binding	GO:0007283//spermatogenesis	--
ENSG00000106688	0.952	1.154	0.759	0.634	1.018	0.954	73	89	43	36	66	40	SLC1A1	solute carrier family 1 member 1 [Source:HGNC Symbol;Acc:HGNC:10939]	Organismal Systems;Organismal Systems;Organismal Systems	Nervous system;Digestive system;Nervous system	ko04724//Glutamatergic synapse;ko04974//Protein digestion and absorption;ko04721//Synaptic vesicle cycle	K05612;K05612;K05612	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0032279//asymmetric synapse;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043083//synaptic cleft;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045121//membrane raft;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0097386//glial cell projection;GO:0097440//apical dendrite;GO:0098793//presynapse;GO:0099544//perisynaptic space;GO:0150002//distal dendrite;GO:1990635//proximal dendrite	GO:0005253//anion channel activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0016595//glutamate binding;GO:0033229//cysteine transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0140010//D-aspartate transmembrane transporter activity	GO:0001662//behavioral fear response;GO:0001932//regulation of protein phosphorylation;GO:0001975//response to amphetamine;GO:0002027//regulation of heart rate;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006801//superoxide metabolic process;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0006882//cellular zinc ion homeostasis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007212//dopamine receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0007611//learning or memory;GO:0007613//memory;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0010460//positive regulation of heart rate;GO:0010467//gene expression;GO:0010842//retina layer formation;GO:0015711//organic anion transport;GO:0015807//L-amino acid transport;GO:0015813//L-glutamate transmembrane transport;GO:0018105//peptidyl-serine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0022008//neurogenesis;GO:0030534//adult behavior;GO:0032148//activation of protein kinase B activity;GO:0034599//cellular response to oxidative stress;GO:0035633//maintenance of blood-brain barrier;GO:0036293//response to decreased oxygen levels;GO:0036475//neuron death in response to oxidative stress;GO:0042417//dopamine metabolic process;GO:0042883//cysteine transport;GO:0043278//response to morphine;GO:0043524//negative regulation of neuron apoptotic process;GO:0045184//establishment of protein localization;GO:0048514//blood vessel morphogenesis;GO:0048678//response to axon injury;GO:0050808//synapse organization;GO:0051938//L-glutamate import;GO:0055085//transmembrane transport;GO:0060013//righting reflex;GO:0060041//retina development in camera-type eye;GO:0060047//heart contraction;GO:0060291//long-term synaptic potentiation;GO:0061744//motor behavior;GO:0070633//transepithelial transport;GO:0070777//D-aspartate transport;GO:0070778//L-aspartate transmembrane transport;GO:0070779//D-aspartate import across plasma membrane;GO:0070997//neuron death;GO:0071242//cellular response to ammonium ion;GO:0071288//cellular response to mercury ion;GO:0071314//cellular response to cocaine;GO:0071407//cellular response to organic cyclic compound;GO:0071577//zinc ion transmembrane transport;GO:0072347//response to anesthetic;GO:0090313//regulation of protein targeting to membrane;GO:0090461//glutamate homeostasis;GO:0097049//motor neuron apoptotic process;GO:0098712//L-glutamate import across plasma membrane;GO:0098877//neurotransmitter receptor transport to plasma membrane;GO:0140009//L-aspartate import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1903712//cysteine transmembrane transport;GO:1903926//cellular response to bisphenol A;GO:1990708//conditioned place preference	--
ENSG00000106689	48.622	44.002	44.23	31.231	33.249	37.383	2233	2090	1575	1106	1381	1331	LHX2	LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:6594]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007498//mesoderm development;GO:0009953//dorsal/ventral pattern formation;GO:0021537//telencephalon development;GO:0021772//olfactory bulb development;GO:0021978//telencephalon regionalization;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0030182//neuron differentiation;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048675//axon extension;GO:0050768//negative regulation of neurogenesis;GO:0060041//retina development in camera-type eye;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000678//negative regulation of transcription regulatory region DNA binding"	Homeobox
ENSG00000106692	5.646	4.505	4.173	3.089	4.347	3.982	802	639	448	346	507	408	FKTN	fukutin [Source:HGNC Symbol;Acc:HGNC:3622]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K19872;K19872	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups"	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0035269//protein O-linked mannosylation;GO:0046329//negative regulation of JNK cascade;GO:0060049//regulation of protein glycosylation	--
ENSG00000106701	1.631	1.381	1.36	1.709	0.887	1.838	187	161	117	124	110	135	FSD1L	fibronectin type III and SPRY domain containing 1 like [Source:HGNC Symbol;Acc:HGNC:13753]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000106714	6.547	7.174	8.245	6.463	6.296	6.271	946.64	930.14	793.12	570.62	670.66	614.98	CNTNAP3	contactin associated protein family member 3 [Source:HGNC Symbol;Acc:HGNC:13834]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007155//cell adhesion;GO:0008037//cell recognition	--
ENSG00000106723	32.253	29.173	30.479	26.318	26.913	29.423	2983	2712	2082	1803	2103	1980	SPIN1	spindlin 1 [Source:HGNC Symbol;Acc:HGNC:11243]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005819//spindle;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007276//gamete generation;GO:0009303//rRNA transcription;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051321//meiotic cell cycle"	--
ENSG00000106733	4.293	4.468	5.136	5.113	4.536	4.534	163	162	134	136	138	119	NMRK1	nicotinamide riboside kinase 1 [Source:HGNC Symbol;Acc:HGNC:26057]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K10524;K10524	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0050262//ribosylnicotinamide kinase activity;GO:0061769//ribosylnicotinate kinase activity	GO:0009435//NAD biosynthetic process;GO:0016310//phosphorylation;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019674//NAD metabolic process	--
ENSG00000106771	52.631	45.043	50.961	48.344	52.401	56.492	5454	4713	4074	3685	4588	4479	TMEM245	transmembrane protein 245 [Source:HGNC Symbol;Acc:HGNC:1363]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000106772	2.753	3.569	1.909	3.573	3.87	2.039	207	271	106	214	234	122	PRUNE2	prune homolog 2 with BCH domain [Source:HGNC Symbol;Acc:HGNC:25209]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016462//pyrophosphatase activity;GO:0046872//metal ion binding	GO:0006915//apoptotic process	--
ENSG00000106780	28.391	26.655	26.204	24.691	27.328	24.327	3710	3501	2529	2390	3017	2313	MEGF9	multiple EGF like domains 9 [Source:HGNC Symbol;Acc:HGNC:3234]	-	-	-	-	GO:0005575//cellular_component;GO:0005604//basement membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0008150//biological_process;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading	--
ENSG00000106785	1.055	1.659	1.107	1.526	1.146	1.124	98	155	76	95	90	76	TRIM14	tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0032897//negative regulation of viral transcription;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity"	--
ENSG00000106789	2.297	2.338	1.807	1.682	1.789	2.283	260	266	151	141	171	188	CORO2A	coronin 2A [Source:HGNC Symbol;Acc:HGNC:2255]	-	-	-	-	GO:0017053//transcription repressor complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0035556//intracellular signal transduction	--
ENSG00000106799	8.774	7.542	9.186	6.338	6.581	6.087	859	838	473	429	522	439	TGFBR1	transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Signal transduction;Cancer: specific types;Signal transduction;Signal transduction;Endocrine system;Development and regeneration;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko04520//Adherens junction	K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674;K04674	GO:0005634//nucleus;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0048179//activin receptor complex;GO:0070021//transforming growth factor beta ligand-receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005102//signaling receptor binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016361//activin receptor activity, type I;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0043167//ion binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding;GO:0070411//I-SMAD binding"	"GO:0001501//skeletal system development;GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0001824//blastocyst development;GO:0001837//epithelial to mesenchymal transition;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002088//lens development in camera-type eye;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008354//germ cell migration;GO:0008584//male gonad development;GO:0009791//post-embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0010604//positive regulation of macromolecule metabolic process;GO:0010628//positive regulation of gene expression;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0031396//regulation of protein ubiquitination;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032924//activin receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042060//wound healing;GO:0042118//endothelial cell activation;GO:0043062//extracellular structure organization;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043393//regulation of protein binding;GO:0043410//positive regulation of MAPK cascade;GO:0043542//endothelial cell migration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0048663//neuron fate commitment;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048762//mesenchymal cell differentiation;GO:0048844//artery morphogenesis;GO:0048870//cell motility;GO:0051171//regulation of nitrogen compound metabolic process;GO:0051173//positive regulation of nitrogen compound metabolic process;GO:0051239//regulation of multicellular organismal process;GO:0051272//positive regulation of cellular component movement;GO:0051491//positive regulation of filopodium assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0060017//parathyroid gland development;GO:0060021//roof of mouth development;GO:0060037//pharyngeal system development;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0070723//response to cholesterol;GO:0071363//cellular response to growth factor stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0080090//regulation of primary metabolic process;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1905075//positive regulation of tight junction disassembly;GO:1905223//epicardium morphogenesis;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000106803	73.423	76.54	79.269	83.435	81.348	82.003	859	900	685	723	804	698	SEC61B	SEC61 translocon subunit beta [Source:HGNC Symbol;Acc:HGNC:16993]	Cellular Processes;Genetic Information Processing;Human Diseases;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation;Infectious disease: bacterial;Folding, sorting and degradation"	ko04145//Phagosome;ko04141//Protein processing in endoplasmic reticulum;ko05110//Vibrio cholerae infection;ko03060//Protein export	K09481;K09481;K09481;K09481	GO:0005783//endoplasmic reticulum;GO:0005784//Sec61 translocon complex;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031205//endoplasmic reticulum Sec complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0048408//epidermal growth factor binding	"GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031204//posttranslational protein targeting to membrane, translocation"	--
ENSG00000106804	1.337	0.876	0.651	0.599	0.829	0.717	158	104	59	55	80	62	C5	complement C5 [Source:HGNC Symbol;Acc:HGNC:1331]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Neurodegenerative disease;Immune system;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03994;K03994;K03994;K03994;K03994;K03994;K03994;K03994;K03994;K03994	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004866//endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008009//chemokine activity	"GO:0001701//in utero embryonic development;GO:0002376//immune system process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010760//negative regulation of macrophage chemotaxis;GO:0010951//negative regulation of endopeptidase activity;GO:0019835//cytolysis;GO:0032722//positive regulation of chemokine production;GO:0045087//innate immune response;GO:0045766//positive regulation of angiogenesis;GO:0060326//cell chemotaxis"	--
ENSG00000106809	0.341	0.272	0.176	0.197	0.154	0.096	21	14	8	9	8	2	OGN	osteoglycin [Source:HGNC Symbol;Acc:HGNC:8126]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0007165//signal transduction;GO:0048662//negative regulation of smooth muscle cell proliferation	--
ENSG00000106819	0.449	0.357	0.396	0.475	0.416	0.697	23	17	15	15	18	26	ASPN	asporin [Source:HGNC Symbol;Acc:HGNC:14872]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0042995//cell projection;GO:0062023//collagen-containing extracellular matrix	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0030282//bone mineralization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031214//biomineral tissue development;GO:0070171//negative regulation of tooth mineralization;GO:1902617//response to fluoride	--
ENSG00000106823	2.098	2.479	1.227	1.318	1.007	1.101	118	143	54	53	49	46	ECM2	extracellular matrix protein 2 [Source:HGNC Symbol;Acc:HGNC:3154]	-	-	-	-	GO:0005576//extracellular region;GO:0005614//interstitial matrix;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0070052//collagen V binding	GO:0007160//cell-matrix adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization	--
ENSG00000106829	20.066	18.315	19.39	15.571	19.06	20.722	1436	1313	1027	850	1078	967	TLE4	"TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:1990907//beta-catenin-TCF complex	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0008150//biological_process;GO:0016055//Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000106852	0.088	0.059	0.02	0.066	0	0.072	6	4	1	3	0	1	LHX6	LIM homeobox 6 [Source:HGNC Symbol;Acc:HGNC:21735]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021800//cerebral cortex tangential migration;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0021884//forebrain neuron development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0048469//cell maturation"	Homeobox
ENSG00000106853	19.03	19.961	19.786	18.532	16.628	22.928	495	525	375	357	365	431	PTGR1	prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0032440//2-alkenal reductase [NAD(P)+] activity;GO:0035798//2-alkenal reductase (NADP+) activity;GO:0036132//13-prostaglandin reductase activity;GO:0036185//13-lipoxin reductase activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity;GO:0097257//leukotriene B4 12-hydroxy dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006693//prostaglandin metabolic process;GO:0036102//leukotriene B4 metabolic process;GO:0097327//response to antineoplastic agent;GO:2001302//lipoxin A4 metabolic process	--
ENSG00000106868	8.016	9.444	10.499	6.619	6.831	7.391	471	505	394	306	326	336	SUSD1	sushi domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25413]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	-	--
ENSG00000106927	0	0	0	0	0	0	0	0	0	0	0	0	AMBP	alpha-1-microglobulin/bikunin precursor [Source:HGNC Symbol;Acc:HGNC:453]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0019855//calcium channel inhibitor activity;GO:0019862//IgA binding;GO:0020037//heme binding;GO:0030414//peptidase inhibitor activity;GO:0042803//protein homodimerization activity;GO:0046904//calcium oxalate binding	GO:0007155//cell adhesion;GO:0007565//female pregnancy;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0018298//protein-chromophore linkage;GO:0030163//protein catabolic process;GO:0042167//heme catabolic process;GO:0046329//negative regulation of JNK cascade;GO:0050777//negative regulation of immune response	--
ENSG00000106948	3.534	3.703	2.972	3.515	2.209	3.079	297	288	204	195	172	191	AKNA	AT-hook transcription factor [Source:HGNC Symbol;Acc:HGNC:24108]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0001837//epithelial to mesenchymal transition;GO:0007399//nervous system development;GO:0021849//neuroblast division in subventricular zone;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0060232//delamination;GO:0060234//neuroblast delamination	Others
ENSG00000106952	0	0	0	0	0	0	0	0	0	0	0	0	TNFSF8	TNF superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11938]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05471	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	"GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0042129//regulation of T cell proliferation;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050830//defense response to Gram-positive bacterium"	--
ENSG00000106976	5.25	4.581	7.688	4.848	5.759	5.152	378	327	259	253	355	273	DNM1	dynamin 1 [Source:HGNC Symbol;Acc:HGNC:2972]	Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Transport and catabolism;Signal transduction;Infectious disease: bacterial;Nervous system;Excretory system	ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K01528;K01528;K01528;K01528;K01528	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098684//photoreceptor ribbon synapse;GO:0098835//presynaptic endocytic zone membrane;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007032//endosome organization;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0031623//receptor internalization;GO:0048488//synaptic vesicle endocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:1901998//toxin transport	--
ENSG00000106991	2.184	2	0.421	2.806	2.78	2.249	133	123	19	127	143	100	ENG	endoglin [Source:HGNC Symbol;Acc:HGNC:3349]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0043235//receptor complex;GO:0072563//endothelial microparticle	GO:0004888//transmembrane signaling receptor activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005534//galactose binding;GO:0005539//glycosaminoglycan binding;GO:0015026//coreceptor activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0036122//BMP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001837//epithelial to mesenchymal transition;GO:0001934//positive regulation of protein phosphorylation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001947//heart looping;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0003148//outflow tract septum morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003203//endocardial cushion morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003273//cell migration involved in endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007507//heart development;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016477//cell migration;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0022009//central nervous system vasculogenesis;GO:0022617//extracellular matrix disassembly;GO:0030155//regulation of cell adhesion;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0031953//negative regulation of protein autophosphorylation;GO:0031960//response to corticosteroid;GO:0032967//positive regulation of collagen biosynthetic process;GO:0035912//dorsal aorta morphogenesis;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042325//regulation of phosphorylation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048745//smooth muscle tissue development;GO:0048844//artery morphogenesis;GO:0048845//venous blood vessel morphogenesis;GO:0048870//cell motility;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0060326//cell chemotaxis;GO:0060348//bone development;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0070278//extracellular matrix constituent secretion;GO:0070483//detection of hypoxia;GO:0071260//cellular response to mechanical stimulus;GO:0071559//response to transforming growth factor beta;GO:0097084//vascular associated smooth muscle cell development;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1905065//positive regulation of vascular associated smooth muscle cell differentiation;GO:1905222//atrioventricular canal morphogenesis"	--
ENSG00000106992	18.286	18.092	20.464	20.613	18.256	16.597	442.56	455.2	376.96	375.74	416.62	340.88	AK1	adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0001520//outer dense fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0036126//sperm flagellum;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006172//ADP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046033//AMP metabolic process;GO:0046034//ATP metabolic process;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000106993	10.639	9.464	7.943	8.802	7.38	9.764	440	388	268	246	265	284	CDC37L1	cell division cycle 37 like 1 [Source:HGNC Symbol;Acc:HGNC:17179]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031089//platelet dense granule lumen	GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0050821//protein stabilization	--
ENSG00000107014	0.855	0.966	0.712	0.977	0.545	0.271	13	15	8	11	7	3	RLN2	relaxin 2 [Source:HGNC Symbol;Acc:HGNC:10027]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K21998;K21998	GO:0005576//extracellular region	GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0010628//positive regulation of gene expression;GO:0045766//positive regulation of angiogenesis;GO:0050790//regulation of catalytic activity	--
ENSG00000107018	0.048	0.143	0	0.065	0.057	0	1	3	0	1	1	0	RLN1	relaxin 1 [Source:HGNC Symbol;Acc:HGNC:10026]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K21998;K21998	GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007565//female pregnancy	--
ENSG00000107020	8.404	8.556	7.852	7.431	7.562	7.903	171	175	118	112	130	117	PLGRKT	plasminogen receptor with a C-terminal lysine [Source:HGNC Symbol;Acc:HGNC:23633]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0010756//positive regulation of plasminogen activation	--
ENSG00000107021	16.346	16.623	16.865	18.639	20.013	17.591	1307	1336	996	1104	1352	1021	TBC1D13	TBC1 domain family member 13 [Source:HGNC Symbol;Acc:HGNC:25571]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006886//intracellular protein transport;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000107036	8.62	7.553	7.952	8.085	8.111	8.36	1120	981	806	704	821	789	RIC1	"RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0032991//protein-containing complex;GO:0034066//Ric1-Rgp1 guanyl-nucleotide exchange factor complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0003330//regulation of extracellular matrix constituent secretion;GO:0006886//intracellular protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0043547//positive regulation of GTPase activity;GO:1903363//negative regulation of cellular protein catabolic process;GO:1904888//cranial skeletal system development"	--
ENSG00000107077	14.333	12.926	13.318	9.706	11.07	10.851	1032	909	676	549	655	580	KDM4C	lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin	GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140684//histone H3-tri/dimethyl-lysine-9 demethylase activity	GO:0001825//blastocyst formation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0016577//histone demethylation;GO:0019827//stem cell population maintenance;GO:0033169//histone H3-K9 demethylation;GO:0051276//chromosome organization;GO:0060765//regulation of androgen receptor signaling pathway;GO:0070544//histone H3-K36 demethylation;GO:1900113//negative regulation of histone H3-K9 trimethylation;GO:2000736//regulation of stem cell differentiation	--
ENSG00000107099	5.465	5.02	5.74	5.699	4.999	6.229	827	771	609	640	620	690	DOCK8	dedicator of cytokinesis 8 [Source:HGNC Symbol;Acc:HGNC:19191]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0031256//leading edge membrane;GO:0031258//lamellipodium membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0001771//immunological synapse formation;GO:0007264//small GTPase mediated signal transduction;GO:0036336//dendritic cell migration;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0061485//memory T cell proliferation;GO:0070233//negative regulation of T cell apoptotic process;GO:1903905//positive regulation of establishment of T cell polarity;GO:1990869//cellular response to chemokine;GO:2000406//positive regulation of T cell migration	--
ENSG00000107104	35.653	35.416	36.629	33.739	34.75	34.699	3738	3773	2804	2694	3155	2654	KANK1	KN motif and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:19309]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008013//beta-catenin binding	GO:0008283//cell population proliferation;GO:0010977//negative regulation of neuron projection development;GO:0030036//actin cytoskeleton organization;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030336//negative regulation of cell migration;GO:0030837//negative regulation of actin filament polymerization;GO:0035023//regulation of Rho protein signal transduction;GO:0035024//negative regulation of Rho protein signal transduction;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090303//positive regulation of wound healing;GO:0090521//glomerular visceral epithelial cell migration;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900028//negative regulation of ruffle assembly;GO:2000114//regulation of establishment of cell polarity;GO:2000393//negative regulation of lamellipodium morphogenesis	--
ENSG00000107105	2.187	2.098	1.716	1.971	2.057	2.088	168	141	100	113	129	110	ELAVL2	ELAV like RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3313]	-	-	-	-	GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000107130	15.342	15.489	16.644	15.798	16.76	17.176	1232	1308	944	985	1188	941	NCS1	neuronal calcium sensor 1 [Source:HGNC Symbol;Acc:HGNC:3953]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0005245//voltage-gated calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0046872//metal ion binding	GO:0010975//regulation of neuron projection development;GO:0031284//positive regulation of guanylate cyclase activity;GO:0070588//calcium ion transmembrane transport	--
ENSG00000107140	15.34	15.413	16.48	16.773	17.578	18.71	805	811	629	652	769	704	TESK1	testis associated actin remodelling kinase 1 [Source:HGNC Symbol;Acc:HGNC:11731]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0031953//negative regulation of protein autophosphorylation;GO:0032880//regulation of protein localization;GO:0032956//regulation of actin cytoskeleton organization;GO:0042326//negative regulation of phosphorylation;GO:0051496//positive regulation of stress fiber assembly;GO:0051650//establishment of vesicle localization;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0090521//glomerular visceral epithelial cell migration;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900182//positive regulation of protein localization to nucleus;GO:1902018//negative regulation of cilium assembly	--
ENSG00000107147	0.007	0.067	0	0.089	0	0.018	1	5	0	3	0	1	KCNT1	potassium sodium-activated channel subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:18865]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005228//intracellular sodium activated potassium channel activity;GO:0005267//potassium channel activity;GO:0015271//outward rectifier potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000107159	52.662	49.862	55.792	76.157	72.732	68.77	1688.71	1607.16	1321.35	1808.96	1970.45	1604.54	CA9	carbonic anhydrase 9 [Source:HGNC Symbol;Acc:HGNC:1383]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0002009//morphogenesis of an epithelium;GO:0006730//one-carbon metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0033574//response to testosterone;GO:0046903//secretion	--
ENSG00000107164	15.912	14.854	15.26	13.799	13.302	16.858	1046	978	741	674	738	810	FUBP3	far upstream element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4005]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000107165	2327.154	2336.294	2360.723	2251.975	2172.738	2331.008	126953	129421	95885	91424	100902	93044	TYRP1	tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Amino acid metabolism	ko01100//Metabolic pathways;ko04916//Melanogenesis;ko00350//Tyrosine metabolism	K00506;K00506;K00506	GO:0005737//cytoplasm;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0097708//intracellular vesicle	GO:0004497//monooxygenase activity;GO:0004503//tyrosinase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006582//melanin metabolic process;GO:0030318//melanocyte differentiation;GO:0032438//melanosome organization;GO:0042438//melanin biosynthetic process;GO:0043438//acetoacetic acid metabolic process;GO:0043473//pigmentation;GO:0048023//positive regulation of melanin biosynthetic process	--
ENSG00000107175	28.102	31.517	28.319	29.933	26.167	26.708	872	983	649	688	686	603	CREB3	cAMP responsive element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2347]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043025//neuronal cell body;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding;GO:0031726//CCR1 chemokine receptor binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001558//regulation of cell growth;GO:0002230//positive regulation of defense response to virus by host;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006935//chemotaxis;GO:0006986//response to unfolded protein;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0019043//establishment of viral latency;GO:0019046//release from viral latency;GO:0030335//positive regulation of cell migration;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034976//response to endoplasmic reticulum stress;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050930//induction of positive chemotaxis;GO:0051928//positive regulation of calcium ion transport;GO:0090026//positive regulation of monocyte chemotaxis;GO:0140467//integrated stress response signaling;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway"	TF_bZIP
ENSG00000107185	9.912	9.309	10.44	10.493	10.085	11.879	1444.88	1364	1124	1133	1242	1260	RGP1	"RGP1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:21965]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0032991//protein-containing complex;GO:0034066//Ric1-Rgp1 guanyl-nucleotide exchange factor complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0042147//retrograde transport, endosome to Golgi;GO:0043547//positive regulation of GTPase activity;GO:1903363//negative regulation of cellular protein catabolic process"	--
ENSG00000107186	26.283	21.864	20.248	15.554	18.723	22.064	3204	2675	1886	1426	2017	2041	MPDZ	multiple PDZ domain crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:7208]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06095	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045177//apical part of cell;GO:0045202//synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0031023//microtubule organizing center organization;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0120192//tight junction assembly	--
ENSG00000107187	0	0	0	0	0	0	0	0	0	0	0	0	LHX3	LIM homeobox 3 [Source:HGNC Symbol;Acc:HGNC:6595]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0021526//medial motor column neuron differentiation;GO:0021527//spinal cord association neuron differentiation;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development"	Homeobox
ENSG00000107201	2.211	2.174	1.613	1.466	1.608	2.109	188.15	196.08	101.54	100	129.76	143	DDX58	DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0009597//detection of virus;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0030334//regulation of cell migration;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034344//regulation of type III interferon production;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0039529//RIG-I signaling pathway;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051607//defense response to virus;GO:0060760//positive regulation of response to cytokine stimulus;GO:0071360//cellular response to exogenous dsRNA;GO:0140374//antiviral innate immune response	--
ENSG00000107223	156.332	170.49	172.016	168.836	157.773	156.023	2157	2367	1759	1729	1842	1573	EDF1	endothelial differentiation related factor 1 [Source:HGNC Symbol;Acc:HGNC:3164]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0001094//TFIID-class transcription factor complex binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005516//calmodulin binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0019216//regulation of lipid metabolic process;GO:0030154//cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0045446//endothelial cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000107242	8.426	7.995	8.981	8.164	7.69	10.354	524	502	412	377	399	464	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995]	Metabolism;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Cell motility;Signal transduction;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cancer: overview;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889	GO:0001931//uropod;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0000285//1-phosphatidylinositol-3-phosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016740//transferase activity;GO:0052810//1-phosphatidylinositol-5-kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000107249	4.482	2.825	3.697	3.728	3.586	3.739	635	435	418	347	406	422	GLIS3	GLIS family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:28510]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000107262	77.754	77.087	76.772	79.843	73.314	80.102	1633	1573	1185	1185	1320	1210	BAG1	BAG cochaperone 1 [Source:HGNC Symbol;Acc:HGNC:937]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09555	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0051087//chaperone binding	GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:1900034//regulation of cellular response to heat	--
ENSG00000107263	19.692	17.879	17.486	21.446	17.204	16.727	1756	1861	1375	1395	1633	1308	RAPGEF1	Rap guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:4568]	Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Cellular community - eukaryotes;Endocrine system;Nervous system;Cancer: specific types	ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04910//Insulin signaling pathway;ko04722//Neurotrophin signaling pathway;ko05211//Renal cell carcinoma	K06277;K06277;K06277;K06277;K06277	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0001568//blood vessel development;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development;GO:0032486//Rap protein signal transduction;GO:0038180//nerve growth factor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0046328//regulation of JNK cascade;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051898//negative regulation of protein kinase B signaling;GO:0061028//establishment of endothelial barrier;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090630//activation of GTPase activity;GO:0098609//cell-cell adhesion;GO:1901888//regulation of cell junction assembly;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000107281	12.798	12.513	11.393	12.277	14.531	12.043	403	395	267	287	389	282	NPDC1	"neural proliferation, differentiation and control 1 [Source:HGNC Symbol;Acc:HGNC:7899]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000107282	1.622	1.89	1.326	4.219	1.626	1.788	222	260	134	242	188	178	APBA1	amyloid beta precursor protein binding family A member 1 [Source:HGNC Symbol;Acc:HGNC:578]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm;GO:0048787//presynaptic active zone membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0006886//intracellular protein transport;GO:0007155//cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007626//locomotory behavior;GO:0008088//axo-dendritic transport;GO:0010468//regulation of gene expression;GO:0014047//glutamate secretion;GO:0014051//gamma-aminobutyric acid secretion;GO:0015031//protein transport;GO:0035264//multicellular organism growth;GO:0065003//protein-containing complex assembly;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000107290	7.103	4.61	4.092	3.503	4.047	3.578	1547	1057	645	559	725	576	SETX	senataxin [Source:HGNC Symbol;Acc:HGNC:445]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K10706	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0045171//intercellular bridge"	GO:0000166//nucleotide binding;GO:0001147//transcription termination site sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	"GO:0000165//MAPK cascade;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006353//DNA-templated transcription, termination;GO:0006369//termination of RNA polymerase II transcription;GO:0006376//mRNA splice site selection;GO:0006396//RNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0007623//circadian rhythm;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010976//positive regulation of neuron projection development;GO:0030154//cell differentiation;GO:0032508//DNA duplex unwinding;GO:0033120//positive regulation of RNA splicing;GO:0034599//cellular response to oxidative stress;GO:0043066//negative regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0060566//positive regulation of DNA-templated transcription, termination;GO:0070301//cellular response to hydrogen peroxide;GO:0071300//cellular response to retinoic acid;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:2000806//positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled"	--
ENSG00000107295	2.063	1.924	2.045	2.039	1.592	1.722	112	105	82	82	73	68	SH3GL2	"SH3 domain containing GRB2 like 2, endophilin A1 [Source:HGNC Symbol;Acc:HGNC:10831]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K11247	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0010629//negative regulation of gene expression;GO:0016191//synaptic vesicle uncoating;GO:0031175//neuron projection development;GO:0097484//dendrite extension;GO:1905604//negative regulation of blood-brain barrier permeability;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus	--
ENSG00000107317	3435.265	3828.676	4026.21	5024.089	4850.001	4364.039	57624.02	64495.1	49833.27	62420	68723	53219	PTGDS	prostaglandin D2 synthase [Source:HGNC Symbol;Acc:HGNC:9592]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K01830;K01830	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004667//prostaglandin-D synthase activity;GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0036094//small molecule binding	"GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0019371//cyclooxygenase pathway;GO:0043303//mast cell degranulation;GO:0045187//regulation of circadian sleep/wake cycle, sleep"	--
ENSG00000107331	108.604	112.397	121.364	130.152	137.269	137.569	18258	18878	15077	16183	19479	16825	ABCA2	ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04142//Lysosome;ko02010//ABC transporters	K05642;K05642	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0061135//endopeptidase regulator activity;GO:0099038//ceramide floppase activity;GO:0140359//ABC-type transporter activity	GO:0001573//ganglioside metabolic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006869//lipid transport;GO:0007626//locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0010872//regulation of cholesterol esterification;GO:0032289//central nervous system myelin formation;GO:0032383//regulation of intracellular cholesterol transport;GO:0032384//negative regulation of intracellular cholesterol transport;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0042632//cholesterol homeostasis;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0048545//response to steroid hormone;GO:0052548//regulation of endopeptidase activity;GO:0055085//transmembrane transport;GO:0060049//regulation of protein glycosylation;GO:0070723//response to cholesterol;GO:0071072//negative regulation of phospholipid biosynthetic process;GO:0090155//negative regulation of sphingolipid biosynthetic process;GO:0090156//cellular sphingolipid homeostasis;GO:0090370//negative regulation of cholesterol efflux;GO:0099040//ceramide translocation;GO:0150104//transport across blood-brain barrier;GO:0150110//negative regulation of cholesterol esterification;GO:1901873//regulation of post-translational protein modification;GO:1902004//positive regulation of amyloid-beta formation;GO:1902993//positive regulation of amyloid precursor protein catabolic process;GO:1904375//regulation of protein localization to cell periphery;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:1905601//negative regulation of receptor-mediated endocytosis involved in cholesterol transport;GO:2000008//regulation of protein localization to cell surface	--
ENSG00000107338	16.225	16.627	18.593	20.998	20.547	23.726	2031	2092	1719	1947	2173	2161	SHB	SH2 domain containing adaptor protein B [Source:HGNC Symbol;Acc:HGNC:10838]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0030154//cell differentiation	--
ENSG00000107341	27.191	27.105	26.245	24.656	25.964	25.649	2525	2530	1800	1696	2037	1733	UBE2R2	ubiquitin conjugating enzyme E2 R2 [Source:HGNC Symbol;Acc:HGNC:19907]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K02207	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000107362	7.292	5.842	8.361	6.646	6.051	7.064	428	340	337	255	289	276	ABHD17B	"abhydrolase domain containing 17B, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:24278]"	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055038//recycling endosome membrane;GO:0098839//postsynaptic density membrane	GO:0008236//serine-type peptidase activity;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity	GO:0002084//protein depalmitoylation;GO:0006508//proteolysis;GO:0099175//regulation of postsynapse organization;GO:1902473//regulation of protein localization to synapse;GO:1902817//negative regulation of protein localization to microtubule;GO:1902950//regulation of dendritic spine maintenance;GO:1905668//positive regulation of protein localization to endosome	--
ENSG00000107371	4.863	4.581	5.035	4.856	5.99	6.831	169	150	124	121	153.04	159	EXOSC3	exosome component 3 [Source:HGNC Symbol;Acc:HGNC:17944]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K03681	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0101019//nucleolar exosome (RNase complex)	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034475//U4 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045006//DNA deamination;GO:0045190//isotype switching;GO:0045830//positive regulation of isotype switching;GO:0071028//nuclear mRNA surveillance;GO:0071034//CUT catabolic process;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing"	--
ENSG00000107372	143.948	132.831	123.268	115.929	127.046	136.165	7413	6617	4533	4346	5390	5066	ZFAND5	zinc finger AN1-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13008]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0001944//vasculature development;GO:0003016//respiratory system process;GO:0008150//biological_process;GO:0010761//fibroblast migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0048745//smooth muscle tissue development;GO:0060324//face development	--
ENSG00000107404	15.847	14.958	17.449	18.298	16.843	20.45	878	955	811	786	892	904	DVL1	dishevelled segment polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:3084]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma;ko04330//Notch signaling pathway	K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:1990909//Wnt signalosome	GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	"GO:0001505//regulation of neurotransmitter levels;GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0007269//neurotransmitter secretion;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007528//neuromuscular junction development;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0021915//neural tube development;GO:0022007//convergent extension involved in neural plate elongation;GO:0031122//cytoplasmic microtubule organization;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032880//regulation of protein localization;GO:0034504//protein localization to nucleus;GO:0035176//social behavior;GO:0035372//protein localization to microtubule;GO:0035556//intracellular signal transduction;GO:0035567//non-canonical Wnt signaling pathway;GO:0043113//receptor clustering;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048668//collateral sprouting;GO:0048675//axon extension;GO:0048813//dendrite morphogenesis;GO:0050808//synapse organization;GO:0050821//protein stabilization;GO:0060029//convergent extension involved in organogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060134//prepulse inhibition;GO:0060997//dendritic spine morphogenesis;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0099054//presynapse assembly;GO:0099173//postsynapse organization;GO:0150012//positive regulation of neuron projection arborization;GO:1905386//positive regulation of protein localization to presynapse;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000107438	15.498	19.374	14.917	17.556	17.785	14.493	460	578	327	386	446	313	PDLIM1	PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067]	-	-	-	-	GO:0001725//stress fiber;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding;GO:0098641//cadherin binding involved in cell-cell adhesion	"GO:0001666//response to hypoxia;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006979//response to oxidative stress;GO:0007507//heart development;GO:0010761//fibroblast migration;GO:0030011//maintenance of cell polarity;GO:0030036//actin cytoskeleton organization;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0043149//stress fiber assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061061//muscle structure development;GO:0098609//cell-cell adhesion"	--
ENSG00000107443	3.156	2.68	3.033	2.004	2.299	2.427	248	213	169	117	154	145	CCNJ	cyclin J [Source:HGNC Symbol;Acc:HGNC:23434]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0044772//mitotic cell cycle phase transition	--
ENSG00000107447	0	0.05	0	0.067	0.03	0.034	0	2	0	2	1	1	DNTT	DNA nucleotidylexotransferase [Source:HGNC Symbol;Acc:HGNC:2983]	Organismal Systems;Genetic Information Processing	Immune system;Replication and repair	ko04640//Hematopoietic cell lineage;ko03450//Non-homologous end-joining	K00977;K00977	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003912//DNA nucleotidylexotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0034061//DNA polymerase activity;GO:0046872//metal ion binding	GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006304//DNA modification;GO:0071897//DNA biosynthetic process	--
ENSG00000107485	0.188	0.072	0	0.049	0.474	0.156	5	4	0	2	22	6	GATA3	GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172]	Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Immune system;Endocrine system;Immune system;Immune disease	"ko04659//Th17 cell differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease"	K17895;K17895;K17895;K17895	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0001709//cell fate determination;GO:0001764//neuron migration;GO:0001775//cell activation;GO:0001806//type IV hypersensitivity;GO:0001817//regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0002088//lens development in camera-type eye;GO:0002376//immune system process;GO:0002520//immune system development;GO:0002572//pro-T cell differentiation;GO:0003180//aortic valve morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003281//ventricular septum development;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009615//response to virus;GO:0009653//anatomical structure morphogenesis;GO:0009791//post-embryonic development;GO:0009967//positive regulation of signal transduction;GO:0010332//response to gamma radiation;GO:0010467//gene expression;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010975//regulation of neuron projection development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030856//regulation of epithelial cell differentiation;GO:0031929//TOR signaling;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0033077//T cell differentiation in thymus;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0035162//embryonic hemopoiesis;GO:0035457//cellular response to interferon-alpha;GO:0035799//ureter maturation;GO:0035898//parathyroid hormone secretion;GO:0042421//norepinephrine biosynthetic process;GO:0042472//inner ear morphogenesis;GO:0043370//regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043523//regulation of neuron apoptotic process;GO:0043583//ear development;GO:0043627//response to estrogen;GO:0045061//thymic T cell selection;GO:0045064//T-helper 2 cell differentiation;GO:0045087//innate immune response;GO:0045165//cell fate commitment;GO:0045471//response to ethanol;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048485//sympathetic nervous system development;GO:0048538//thymus development;GO:0048568//embryonic organ development;GO:0048589//developmental growth;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048872//homeostasis of number of cells;GO:0050728//negative regulation of inflammatory response;GO:0050852//T cell receptor signaling pathway;GO:0051569//regulation of histone H3-K4 methylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0060017//parathyroid gland development;GO:0060037//pharyngeal system development;GO:0060065//uterus development;GO:0060231//mesenchymal to epithelial transition;GO:0060374//mast cell differentiation;GO:0060676//ureteric bud formation;GO:0061085//regulation of histone H3-K27 methylation;GO:0061290//canonical Wnt signaling pathway involved in metanephric kidney development;GO:0071345//cellular response to cytokine stimulus;GO:0071353//cellular response to interleukin-4;GO:0071356//cellular response to tumor necrosis factor;GO:0071442//positive regulation of histone H3-K14 acetylation;GO:0071599//otic vesicle development;GO:0071773//cellular response to BMP stimulus;GO:0072107//positive regulation of ureteric bud formation;GO:0072178//nephric duct morphogenesis;GO:0072179//nephric duct formation;GO:0072182//regulation of nephron tubule epithelial cell differentiation;GO:0072197//ureter morphogenesis;GO:0072676//lymphocyte migration;GO:0090102//cochlea development;GO:1901536//negative regulation of DNA demethylation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:2000114//regulation of establishment of cell polarity;GO:2000146//negative regulation of cell motility;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2000607//negative regulation of cell proliferation involved in mesonephros development;GO:2000611//positive regulation of thyroid hormone generation;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2000683//regulation of cellular response to X-ray;GO:2000703//negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation;GO:2000734//negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation"	zf-GATA
ENSG00000107518	11.819	9.226	10.988	9.701	10.204	10.708	910	762	554	503	596	574	ATRNL1	attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063]	-	-	-	-	GO:0005604//basement membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading	--
ENSG00000107521	16.708	16.646	17.061	19.258	20.766	18.938	1019	942	737	882	983	794	HPS1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 [Source:HGNC Symbol;Acc:HGNC:5163]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0031085//BLOC-3 complex;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	GO:0007040//lysosome organization;GO:0007601//visual perception;GO:0016192//vesicle-mediated transport;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000107537	14.43	12.652	12.757	12.991	12.811	14.242	432	406	303	310	340	334	PHYH	phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K00477	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0097731//9+0 non-motile cilium	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0031406//carboxylic acid binding;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0048244//phytanoyl-CoA dioxygenase activity;GO:0051213//dioxygenase activity	GO:0001561//fatty acid alpha-oxidation;GO:0006103//2-oxoglutarate metabolic process;GO:0006631//fatty acid metabolic process;GO:0006720//isoprenoid metabolic process;GO:0019606//2-oxobutyrate catabolic process;GO:0097089//methyl-branched fatty acid metabolic process	--
ENSG00000107551	7.742	7.665	9.575	7.062	7.384	8.541	534	476	434	360	398	371	RASSF4	Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793]	Environmental Information Processing	Signal transduction	ko04392//Hippo signaling pathway - multiple species	K09851	-	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007165//signal transduction	--
ENSG00000107554	2.81	3.637	3.143	3.87	3.98	3.472	374	478	293	328	415	316	DNMBP	dynamin binding protein [Source:HGNC Symbol;Acc:HGNC:30373]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0030054//cell junction;GO:0045202//synapse;GO:0098793//presynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007568//aging;GO:0008360//regulation of cell shape;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000107560	6.749	3.952	4.731	3.596	4.309	5.038	886	524	461	351	480	482	RAB11FIP2	RAB11 family interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:29152]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12484	GO:0001891//phagocytic cup;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006909//phagocytosis;GO:0015031//protein transport;GO:0030010//establishment of cell polarity;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0043547//positive regulation of GTPase activity;GO:0045055//regulated exocytosis	--
ENSG00000107562	2.881	3.164	2.767	4.397	3.627	4.222	132	142	89	146	137	125	CXCL12	C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Cell motility;Immune system;Development and regeneration;Signal transduction;Immune disease;Immune system;Immune system;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04064//NF-kappa B signaling pathway;ko05323//Rheumatoid arthritis;ko04672//Intestinal immune network for IgA production;ko04670//Leukocyte transendothelial migration;ko04061//Viral protein interaction with cytokine and cytokine receptor	K10031;K10031;K10031;K10031;K10031;K10031;K10031;K10031;K10031;K10031;K10031	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008083//growth factor activity;GO:0042379//chemokine receptor binding;GO:0045236//CXCR chemokine receptor binding	GO:0001666//response to hypoxia;GO:0001764//neuron migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007411//axon guidance;GO:0007420//brain development;GO:0008015//blood circulation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008284//positive regulation of cell population proliferation;GO:0008344//adult locomotory behavior;GO:0009314//response to radiation;GO:0009408//response to heat;GO:0009612//response to mechanical stimulus;GO:0009615//response to virus;GO:0022029//telencephalon cell migration;GO:0030335//positive regulation of cell migration;GO:0031100//animal organ regeneration;GO:0033603//positive regulation of dopamine secretion;GO:0033622//integrin activation;GO:0038146//chemokine (C-X-C motif) ligand 12 signaling pathway;GO:0043434//response to peptide hormone;GO:0045666//positive regulation of neuron differentiation;GO:0045785//positive regulation of cell adhesion;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0050930//induction of positive chemotaxis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051924//regulation of calcium ion transport;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0090026//positive regulation of monocyte chemotaxis;GO:0090280//positive regulation of calcium ion import;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1903237//negative regulation of leukocyte tethering or rolling;GO:1990478//response to ultrasound;GO:1990869//cellular response to chemokine;GO:2000406//positive regulation of T cell migration;GO:2000669//negative regulation of dendritic cell apoptotic process	--
ENSG00000107566	17.302	17.547	17.263	15.094	17.025	13.808	918	898	678	583	745	577	ERLIN1	ER lipid raft associated 1 [Source:HGNC Symbol;Acc:HGNC:16947]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0031625//ubiquitin protein ligase binding	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032933//SREBP signaling pathway;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0045717//negative regulation of fatty acid biosynthetic process	--
ENSG00000107581	52.771	48.386	40.712	29.742	33.92	34.419	5441	4967	3174	2291	2975	2652	EIF3A	eukaryotic translation initiation factor 3 subunit A [Source:HGNC Symbol;Acc:HGNC:3271]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0005874//microtubule;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0043614//multi-eIF complex;GO:0071540//eukaryotic translation initiation factor 3 complex, eIF3e;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0002188//translation reinitiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0075522//IRES-dependent viral translational initiation;GO:0075525//viral translational termination-reinitiation	--
ENSG00000107593	0	0	0	0	0.025	0	0	0	0	0	1	0	PKD2L1	"polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011]"	Organismal Systems	Sensory system	ko04742//Taste transduction	K04990	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0034703//cation channel complex;GO:0034704//calcium channel complex;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0005227//calcium activated cation channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005272//sodium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008324//cation transmembrane transporter activity;GO:0015269//calcium-activated potassium channel activity;GO:0033040//sour taste receptor activity;GO:0042802//identical protein binding;GO:0051371//muscle alpha-actinin binding;GO:0051393//alpha-actinin binding	GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0007224//smoothened signaling pathway;GO:0009415//response to water;GO:0035725//sodium ion transmembrane transport;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0050915//sensory perception of sour taste;GO:0050982//detection of mechanical stimulus;GO:0051262//protein tetramerization;GO:0051289//protein homotetramerization;GO:0070588//calcium ion transmembrane transport;GO:0071467//cellular response to pH;GO:0071468//cellular response to acidic pH;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000107611	6.015	6.467	5.889	10.123	9.043	8.733	1488	1608	1076	1855	1890	1572	CUBN	cubilin [Source:HGNC Symbol;Acc:HGNC:2548]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14616	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005905//clathrin-coated pit;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0043202//lysosomal lumen;GO:0043235//receptor complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031419//cobalamin binding;GO:0038023//signaling receptor activity;GO:0038024//cargo receptor activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001894//tissue homeostasis;GO:0006629//lipid metabolic process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009235//cobalamin metabolic process;GO:0009617//response to bacterium;GO:0015031//protein transport;GO:0015889//cobalamin transport;GO:0042953//lipoprotein transport	--
ENSG00000107614	2.591	1.708	1.929	1.391	1.909	1.744	134	126	73	79	81	85	TRDMT1	tRNA aspartic acid methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2977]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0016740//transferase activity	GO:0001975//response to amphetamine;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0036416//tRNA stabilization	--
ENSG00000107625	15.772	13.106	14.064	11.698	11.606	12.289	714	637	512	424	472	429	DDX50	DExD-box helicase 50 [Source:HGNC Symbol;Acc:HGNC:17906]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000107643	6.852	7.606	7.05	5.013	4.857	6.406	452	432	315	250	273	258	MAPK8	mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	"Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Immune system;Cellular community - eukaryotes;Signal transduction;Folding, sorting and degradation;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Transport and catabolism;Nervous system;Infectious disease: viral;Neurodegenerative disease;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Endocrine system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Immune system;Endocrine system;Cancer: specific types;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Endocrine system;Transport and catabolism;Immune system;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Cell growth and death"	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04530//Tight junction;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko05212//Pancreatic cancer;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus;ko04215//Apoptosis - multiple species"	K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030054//cell junction;GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0097441//basal dendrite	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004705//JUN kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0035033//histone deacetylase regulator activity;GO:0042826//histone deacetylase binding;GO:0106310//protein serine kinase activity;GO:0120283//protein serine/threonine kinase binding	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007258//JUN phosphorylation;GO:0009411//response to UV;GO:0009612//response to mechanical stimulus;GO:0010628//positive regulation of gene expression;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0031063//regulation of histone deacetylation;GO:0031281//positive regulation of cyclase activity;GO:0031343//positive regulation of cell killing;GO:0032091//negative regulation of protein binding;GO:0032880//regulation of protein localization;GO:0034198//cellular response to amino acid starvation;GO:0034614//cellular response to reactive oxygen species;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0048511//rhythmic process;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051247//positive regulation of protein metabolic process;GO:0051403//stress-activated MAPK cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0071276//cellular response to cadmium ion;GO:0090045//positive regulation of deacetylase activity;GO:0090398//cellular senescence;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1902595//regulation of DNA replication origin binding	--
ENSG00000107651	9.635	8.663	9.568	7.872	8.975	8.717	1341	1291	982	816	995	865	SEC23IP	SEC23 interacting protein [Source:HGNC Symbol;Acc:HGNC:17018]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0004620//phospholipase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization	--
ENSG00000107669	15.103	12.169	14.676	10.235	11.42	13.256	1523	1182	952	742	888	902	ATE1	arginyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:782]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004057//arginyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0010498//proteasomal protein catabolic process;GO:0016598//protein arginylation	--
ENSG00000107672	7.385	7.827	10.043	7.516	6.083	8.431	212	227	214	159	148	177	NSMCE4A	"NSE4 homolog A, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:25935]"	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0030915//Smc5-Smc6 complex"	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0032204//regulation of telomere maintenance;GO:2001022//positive regulation of response to DNA damage stimulus	--
ENSG00000107679	13.051	10.322	13.59	10.571	11.441	13.058	943	774	594	551	650	626	PLEKHA1	pleckstrin homology domain containing A1 [Source:HGNC Symbol;Acc:HGNC:14335]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030165//PDZ domain binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0001553//luteinization;GO:0007283//spermatogenesis;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0008585//female gonad development;GO:0009791//post-embryonic development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0031529//ruffle organization;GO:0033327//Leydig cell differentiation;GO:0035264//multicellular organism growth;GO:0045184//establishment of protein localization;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0050853//B cell receptor signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0070301//cellular response to hydrogen peroxide	--
ENSG00000107719	5.302	4.89	6.372	6.438	6.672	6.525	507	470	450	456	539	454	PALD1	phosphatase domain containing paladin 1 [Source:HGNC Symbol;Acc:HGNC:23530]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding	GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000107731	14.095	13.986	13.702	21.067	22.239	22.705	1957	1961	1402	2173	2623	2323	UNC5B	unc-5 netrin receptor B [Source:HGNC Symbol;Acc:HGNC:12568]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07521	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005042//netrin receptor activity;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0033564//anterior/posterior axon guidance;GO:0038007//netrin-activated signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000107736	0.824	0.841	1.488	1.276	1.132	1.116	86	96	90	82	109	89	CDH23	cadherin related 23 [Source:HGNC Symbol;Acc:HGNC:13733]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0045202//synapse;GO:0060091//kinocilium;GO:0098683//cochlear hair cell ribbon synapse;GO:0098684//photoreceptor ribbon synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006816//calcium ion transport;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0042472//inner ear morphogenesis;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0048563//post-embryonic animal organ morphogenesis;GO:0048839//inner ear development;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0060088//auditory receptor cell stereocilium organization;GO:0060122//inner ear receptor cell stereocilium organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000107738	5.042	5.159	7.145	8.436	8.486	8.49	493	507	516	611	701	604	VSIR	V-set immunoregulatory receptor [Source:HGNC Symbol;Acc:HGNC:30085]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K23268	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0061133//endopeptidase activator activity	"GO:0010628//positive regulation of gene expression;GO:0010950//positive regulation of endopeptidase activity;GO:0030335//positive regulation of cell migration;GO:0031638//zymogen activation;GO:0032689//negative regulation of interferon-gamma production;GO:0032693//negative regulation of interleukin-10 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0050776//regulation of immune response;GO:0120158//positive regulation of collagen catabolic process;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000565//negative regulation of CD8-positive, alpha-beta T cell proliferation"	--
ENSG00000107742	0.415	0.377	0.4	2.732	2.39	1.765	45	36	32	220	208	135	SPOCK2	"SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:13564]"	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0050840//extracellular matrix binding	GO:0007416//synapse assembly;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010951//negative regulation of endopeptidase activity;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0030198//extracellular matrix organization;GO:0045595//regulation of cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000147//positive regulation of cell motility	--
ENSG00000107745	23.699	24.222	22.507	21.736	23.618	25.007	1136	1174	794	773	948	863	MICU1	mitochondrial calcium uptake 1 [Source:HGNC Symbol;Acc:HGNC:1530]	-	-	-	-	GO:0005622//intracellular anatomical structure;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032592//integral component of mitochondrial membrane;GO:0034704//calcium channel complex;GO:1990246//uniplex complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006952//defense response;GO:0036444//calcium import into the mitochondrion;GO:0051260//protein homooligomerization;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0070509//calcium ion import;GO:1900069//regulation of cellular hyperosmotic salinity response	--
ENSG00000107758	22.902	22.064	21.437	18.798	18.189	20.579	1432	1405	1005	890	961	943	PPP3CB	protein phosphatase 3 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9315]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cell growth and death;Nervous system;Development and regeneration;Nervous system;Immune system;Immune system;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Substance dependence;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04380//Osteoclast differentiation;ko04724//Glutamatergic synapse;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04370//VEGF signaling pathway	K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005955//calcineurin complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0098978//glutamatergic synapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030346//protein phosphatase 2B binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0001946//lymphangiogenesis;GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0007507//heart development;GO:0007612//learning;GO:0007613//memory;GO:0010468//regulation of gene expression;GO:0016311//dephosphorylation;GO:0017156//calcium-ion regulated exocytosis;GO:0023057//negative regulation of signaling;GO:0030217//T cell differentiation;GO:0031987//locomotion involved in locomotory behavior;GO:0033173//calcineurin-NFAT signaling cascade;GO:0034097//response to cytokine;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042098//T cell proliferation;GO:0042110//T cell activation;GO:0043029//T cell homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0048675//axon extension;GO:0048741//skeletal muscle fiber development;GO:0050796//regulation of insulin secretion;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0097720//calcineurin-mediated signaling;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane"	--
ENSG00000107771	18.44	17.268	15.685	11.525	21.962	16.452	1747	1440	1127	894	1111	1072	CCSER2	coiled-coil serine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:29197]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton	GO:0008017//microtubule binding	GO:0001578//microtubule bundle formation	--
ENSG00000107779	10.903	12.213	15.766	9.341	9.418	13.354	937	911	671	486	603	657	BMPR1A	bone morphogenetic protein receptor type 1A [Source:HGNC Symbol;Acc:HGNC:1076]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K04673;K04673;K04673;K04673;K04673	GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:1990712//HFE-transferrin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019211//phosphatase activator activity;GO:0036122//BMP binding;GO:0042803//protein homodimerization activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0098821//BMP receptor activity"	GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0001756//somitogenesis;GO:0001880//Mullerian duct regression;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002062//chondrocyte differentiation;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003161//cardiac conduction system development;GO:0003171//atrioventricular valve development;GO:0003183//mitral valve morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0003272//endocardial cushion formation;GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007389//pattern specification process;GO:0007398//ectoderm development;GO:0007399//nervous system development;GO:0007492//endoderm development;GO:0007507//heart development;GO:0009950//dorsal/ventral axis specification;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0010629//negative regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014032//neural crest cell development;GO:0014912//negative regulation of smooth muscle cell migration;GO:0016310//phosphorylation;GO:0019827//stem cell population maintenance;GO:0021983//pituitary gland development;GO:0021998//neural plate mediolateral regionalization;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0035137//hindlimb morphogenesis;GO:0035912//dorsal aorta morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048339//paraxial mesoderm development;GO:0048352//paraxial mesoderm structural organization;GO:0048368//lateral mesoderm development;GO:0048378//regulation of lateral mesodermal cell fate specification;GO:0048382//mesendoderm development;GO:0048568//embryonic organ development;GO:0048589//developmental growth;GO:0048598//embryonic morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050768//negative regulation of neurogenesis;GO:0050790//regulation of catalytic activity;GO:0051148//negative regulation of muscle cell differentiation;GO:0051216//cartilage development;GO:0060021//roof of mouth development;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0060896//neural plate pattern specification;GO:0060914//heart formation;GO:0060928//atrioventricular node cell development;GO:0061312//BMP signaling pathway involved in heart development;GO:0061626//pharyngeal arch artery morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0071773//cellular response to BMP stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904414//positive regulation of cardiac ventricle development;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905285//fibrous ring of heart morphogenesis;GO:2000772//regulation of cellular senescence	--
ENSG00000107789	11.257	10.477	11.552	11.042	10.829	13.374	576	538	436	417	468	498	MINPP1	multiple inositol-polyphosphate phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:7102]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism;ko00010//Glycolysis / Gluconeogenesis	K03103;K03103;K03103	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	"GO:0003993//acid phosphatase activity;GO:0004446//inositol-hexakisphosphate phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030351//inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity;GO:0034417//bisphosphoglycerate 3-phosphatase activity;GO:0051717//inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity;GO:0052745//inositol phosphate phosphatase activity;GO:0052826//inositol hexakisphosphate 2-phosphatase activity;GO:0101006//protein histidine phosphatase activity"	GO:0001503//ossification;GO:0006470//protein dephosphorylation;GO:0006797//polyphosphate metabolic process;GO:0016311//dephosphorylation;GO:0030282//bone mineralization;GO:0043647//inositol phosphate metabolic process	--
ENSG00000107796	145.771	157.086	122.466	79.03	96.429	69.545	4073	4418	2530	1638	2277	1410	ACTA2	"actin alpha 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:130]"	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway	K12313;K12313;K12313	GO:0001725//stress fiber;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030485//smooth muscle contractile fiber;GO:0032991//protein-containing complex;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding	GO:0006936//muscle contraction;GO:0008217//regulation of blood pressure;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0014829//vascular associated smooth muscle contraction;GO:0061041//regulation of wound healing;GO:0061870//positive regulation of hepatic stellate cell migration;GO:0061874//positive regulation of hepatic stellate cell contraction;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072144//glomerular mesangial cell development;GO:0090131//mesenchyme migration;GO:2000491//positive regulation of hepatic stellate cell activation	--
ENSG00000107798	20.063	22.195	22.622	22.765	23.478	26.586	993	1155	865	873	1027	946	LIPA	"lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617]"	Cellular Processes;Organismal Systems;Metabolism	Transport and catabolism;Digestive system;Lipid metabolism	ko04142//Lysosome;ko04979//Cholesterol metabolism;ko00100//Steroid biosynthesis	K01052;K01052;K01052	GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle	"GO:0004771//sterol esterase activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0000902//cell morphogenesis;GO:0006629//lipid metabolic process;GO:0006954//inflammatory response;GO:0008283//cell population proliferation;GO:0016042//lipid catabolic process;GO:0016125//sterol metabolic process;GO:0030324//lung development;GO:0034383//low-density lipoprotein particle clearance;GO:0048771//tissue remodeling;GO:0048873//homeostasis of number of cells within a tissue	--
ENSG00000107807	0	0	0	0	0	0	0	0	0	0	0	0	TLX1	T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09340	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development"	Homeobox
ENSG00000107815	6.507	4.871	3.726	3.724	5.806	3.91	248	300	205	191	254	209	TWNK	twinkle mtDNA helicase [Source:HGNC Symbol;Acc:HGNC:1160]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K17680	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0043139//5'-3' DNA helicase activity	GO:0006260//DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006390//mitochondrial transcription;GO:0032508//DNA duplex unwinding;GO:0034214//protein hexamerization;GO:0071333//cellular response to glucose stimulus	--
ENSG00000107816	33.564	31.03	36.588	39.751	45.51	40.419	1866	1837	1431	1602	1836	1570	LZTS2	leucine zipper tumor suppressor 2 [Source:HGNC Symbol;Acc:HGNC:29381]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0031982//vesicle	GO:0005515//protein binding	GO:0000281//mitotic cytokinesis;GO:0001822//kidney development;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051013//microtubule severing;GO:0051168//nuclear export;GO:0051255//spindle midzone assembly;GO:0051301//cell division;GO:0060682//primary ureteric bud growth;GO:0072197//ureter morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000107819	17.009	19.369	17.805	16.975	18.512	17.59	1093	1251	845	808	1005	796	SFXN3	sideroflexin 3 [Source:HGNC Symbol;Acc:HGNC:16087]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0015075//ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022889//serine transmembrane transporter activity	GO:0006730//one-carbon metabolic process;GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0140300//serine import into mitochondrion;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000107821	2.745	3.087	2.747	1.39	1.501	2.071	184	208	136	69	85	101	KAZALD1	Kazal type serine peptidase inhibitor domain 1 [Source:HGNC Symbol;Acc:HGNC:25460]	-	-	-	-	GO:0005576//extracellular region;GO:0005614//interstitial matrix;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding	GO:0001503//ossification;GO:0001558//regulation of cell growth;GO:0009966//regulation of signal transduction;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization	--
ENSG00000107829	15.406	14.145	14.315	15.388	14.803	13.341	765	706	525	566	621	482	FBXW4	F-box and WD repeat domain containing 4 [Source:HGNC Symbol;Acc:HGNC:10847]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0030326//embryonic limb morphogenesis;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042733//embryonic digit morphogenesis;GO:0043687//post-translational protein modification;GO:0051216//cartilage development;GO:0060173//limb development	--
ENSG00000107831	0	0	0.094	0	0	0	0	0	1	0	0	0	FGF8	fibroblast growth factor 8 [Source:HGNC Symbol;Acc:HGNC:3686]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008083//growth factor activity	GO:0000165//MAPK cascade;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001759//organ induction;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0001839//neural plate morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001947//heart looping;GO:0001974//blood vessel remodeling;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0007165//signal transduction;GO:0007368//determination of left/right symmetry;GO:0007369//gastrulation;GO:0007507//heart development;GO:0008078//mesodermal cell migration;GO:0008284//positive regulation of cell population proliferation;GO:0008406//gonad development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0009887//animal organ morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0010628//positive regulation of gene expression;GO:0021537//telencephalon development;GO:0021543//pallium development;GO:0021544//subpallium development;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021846//cell proliferation in forebrain;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0030539//male genitalia development;GO:0030878//thyroid gland development;GO:0030916//otic vesicle formation;GO:0030917//midbrain-hindbrain boundary development;GO:0035050//embryonic heart tube development;GO:0035108//limb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035909//aorta morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042476//odontogenesis;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045165//cell fate commitment;GO:0045597//positive regulation of cell differentiation;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0045840//positive regulation of mitotic nuclear division;GO:0046622//positive regulation of organ growth;GO:0048699//generation of neurons;GO:0048702//embryonic neurocranium morphogenesis;GO:0048853//forebrain morphogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0055026//negative regulation of cardiac muscle tissue development;GO:0060037//pharyngeal system development;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0060348//bone development;GO:0060425//lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060563//neuroepithelial cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071542//dopaminergic neuron differentiation;GO:0090134//cell migration involved in mesendoderm migration;GO:0120223//larynx morphogenesis	--
ENSG00000107833	11.215	11.485	10.421	13.73	13.014	11.862	204	210	140	185	200	157	NPM3	nucleophosmin/nucleoplasmin 3 [Source:HGNC Symbol;Acc:HGNC:7931]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006338//chromatin remodeling;GO:0006364//rRNA processing;GO:0009303//rRNA transcription	--
ENSG00000107854	17.046	13.939	14.202	11.981	13.101	14.904	2207	1814	1358	1149	1433	1404	TNKS2	tankyrase 2 [Source:HGNC Symbol;Acc:HGNC:15677]	-	-	-	-	"GO:0000139//Golgi membrane;GO:0000242//pericentriolar material;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm"	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:1990404//protein ADP-ribosylase activity	"GO:0000209//protein polyubiquitination;GO:0006471//protein ADP-ribosylation;GO:0016055//Wnt signaling pathway;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035264//multicellular organism growth;GO:0040014//regulation of multicellular organism growth;GO:0070198//protein localization to chromosome, telomeric region;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904355//positive regulation of telomere capping;GO:1904357//negative regulation of telomere maintenance via telomere lengthening"	--
ENSG00000107859	0.203	0.334	0.183	0	0.12	0.139	5	9	4	0	3	3	PITX3	paired like homeodomain 3 [Source:HGNC Symbol;Acc:HGNC:9006]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002088//lens development in camera-type eye;GO:0002089//lens morphogenesis in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007568//aging;GO:0007626//locomotory behavior;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010468//regulation of gene expression;GO:0014014//negative regulation of gliogenesis;GO:0030901//midbrain development;GO:0035902//response to immobilization stress;GO:0042220//response to cocaine;GO:0043278//response to morphine;GO:0043525//positive regulation of neuron apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048666//neuron development;GO:0050768//negative regulation of neurogenesis;GO:0070306//lens fiber cell differentiation;GO:0071542//dopaminergic neuron differentiation;GO:1904313//response to methamphetamine hydrochloride;GO:1904935//positive regulation of cell proliferation in midbrain;GO:1990792//cellular response to glial cell derived neurotrophic factor"	Homeobox
ENSG00000107862	26.769	29.508	28.103	29.062	29.323	28.875	3472	3694	2738	2655	3120	2480	GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:4181]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18443	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0098791//Golgi apparatus subcompartment;GO:0110165//cellular anatomical entity	"GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	"GO:0002263//cell activation involved in immune response;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006895//Golgi to endosome transport;GO:0007030//Golgi organization;GO:0007346//regulation of mitotic cell cycle;GO:0015031//protein transport;GO:0030593//neutrophil chemotaxis;GO:0032012//regulation of ARF protein signal transduction;GO:0034067//protein localization to Golgi apparatus;GO:0042147//retrograde transport, endosome to Golgi;GO:0048205//COPI coating of Golgi vesicle;GO:0050790//regulation of catalytic activity;GO:0060271//cilium assembly;GO:0061162//establishment of monopolar cell polarity;GO:0070973//protein localization to endoplasmic reticulum exit site;GO:0090166//Golgi disassembly;GO:0097111//endoplasmic reticulum-Golgi intermediate compartment organization;GO:0098586//cellular response to virus;GO:1903409//reactive oxygen species biosynthetic process;GO:1903420//protein localization to endoplasmic reticulum tubular network;GO:2000008//regulation of protein localization to cell surface"	--
ENSG00000107863	13.152	9.854	9.347	6.215	7.627	8.047	1875	1448	986	661	903	838	ARHGAP21	Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:HGNC:23725]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051645//Golgi localization;GO:0051683//establishment of Golgi localization;GO:0051684//maintenance of Golgi location;GO:0072384//organelle transport along microtubule	--
ENSG00000107864	0.845	0.761	0.725	0.976	1.061	1.078	113	101	69	96	119	104	CPEB3	cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:21746]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K02602;K02602	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0030014//CCR4-NOT complex;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030496//midbody;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0097440//apical dendrite;GO:0098794//postsynapse;GO:1990124//messenger ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0035613//RNA stem-loop binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0043022//ribosome binding;GO:0045182//translation regulator activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006412//translation;GO:0006417//regulation of translation;GO:0007616//long-term memory;GO:0017148//negative regulation of translation;GO:0045727//positive regulation of translation;GO:0048167//regulation of synaptic plasticity;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0060998//regulation of dendritic spine development;GO:0060999//positive regulation of dendritic spine development;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0071230//cellular response to amino acid stimulus;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1900248//negative regulation of cytoplasmic translational elongation;GO:1900365//positive regulation of mRNA polyadenylation;GO:2000766//negative regulation of cytoplasmic translation"	--
ENSG00000107872	9.029	9.182	11.735	13.058	10.807	11.574	220	227	213	252	233	221	FBXL15	F-box and leucine rich repeat protein 15 [Source:HGNC Symbol;Acc:HGNC:28155]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0009953//dorsal/ventral pattern formation;GO:0016567//protein ubiquitination;GO:0030282//bone mineralization;GO:0030513//positive regulation of BMP signaling pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000107874	48.299	52.718	55.308	63.844	57.739	52.888	1102	1209	932	1079	1113	878	CUEDC2	CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0010936//negative regulation of macrophage cytokine production;GO:1900016//negative regulation of cytokine production involved in inflammatory response	--
ENSG00000107882	10.253	11.305	11.75	13.884	13.181	12.638	1049	1167	897	1067	1151	955	SUFU	SUFU negative regulator of hedgehog signaling [Source:HGNC Symbol;Acc:HGNC:16466]	Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K06229;K06229;K06229	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:1990788//GLI-SUFU complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001843//neural tube closure;GO:0001947//heart looping;GO:0003281//ventricular septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007224//smoothened signaling pathway;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0021513//spinal cord dorsal/ventral patterning;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0035904//aorta development;GO:0042308//negative regulation of protein import into nucleus;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043588//skin development;GO:0045668//negative regulation of osteoblast differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0060976//coronary vasculature development;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1990787//negative regulation of hh target transcription factor activity;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000107890	0.894	0.624	0.62	0.475	0.461	0.605	113	81	38	42	51	54	ANKRD26	ankyrin repeat domain 26 [Source:HGNC Symbol;Acc:HGNC:29186]	-	-	-	-	GO:0005813//centrosome	GO:0005515//protein binding	GO:0045599//negative regulation of fat cell differentiation	--
ENSG00000107897	19.268	16.098	17.741	13.362	13.614	17.974	1351	1148	908.02	692	810	939.02	ACBD5	acyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23338]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000062//fatty-acyl-CoA binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006631//fatty acid metabolic process;GO:0006914//autophagy;GO:0030242//autophagy of peroxisome	--
ENSG00000107902	7.662	8.425	9.993	11.318	11.36	9.593	244	287	227	251	272	218	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase [Source:HGNC Symbol;Acc:HGNC:30042]	Metabolism	Energy metabolism	ko00190//Oxidative phosphorylation	K11725	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0004427//inorganic diphosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006796//phosphate-containing compound metabolic process;GO:0016311//dephosphorylation	--
ENSG00000107929	11.49	10.352	12.7	9.783	11.909	9.387	1164	1086	800	676	903	732	LARP4B	La ribonucleoprotein 4B [Source:HGNC Symbol;Acc:HGNC:28987]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0042788//polysomal ribosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0045727//positive regulation of translation;GO:1905870//positive regulation of 3'-UTR-mediated mRNA stabilization	--
ENSG00000107937	6.71	6.346	6.253	5.116	6.268	5.792	648	616	446	366	509.78	407	GTPBP4	GTP binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21535]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K06943	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0001649//osteoblast differentiation;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell population proliferation;GO:0022408//negative regulation of cell-cell adhesion;GO:0030336//negative regulation of cell migration;GO:0031397//negative regulation of protein ubiquitination;GO:0033342//negative regulation of collagen binding;GO:0042254//ribosome biogenesis;GO:0050821//protein stabilization"	--
ENSG00000107938	3.607	2.81	3.086	2.814	3.019	3.461	301	247	205	181	208	213	EDRF1	erythroid differentiation regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:24640]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0005515//protein binding	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000107949	21.323	20.64	25.385	16.264	17.987	22.999	727	694.51	612.61	423	494.3	543.58	BCCIP	BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0097431//mitotic spindle pole	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019207//kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000132//establishment of mitotic spindle orientation;GO:0000226//microtubule cytoskeleton organization;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0034453//microtubule anchoring;GO:0061101//neuroendocrine cell differentiation;GO:0090307//mitotic spindle assembly	--
ENSG00000107951	3.058	2.565	2.513	3.069	3.559	3.327	263	235	159	169	190	190	MTPAP	mitochondrial poly(A) polymerase [Source:HGNC Symbol;Acc:HGNC:25532]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0002134//UTP binding;GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:1990817//RNA adenylyltransferase activity	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0031123//RNA 3'-end processing;GO:0071044//histone mRNA catabolic process	--
ENSG00000107954	0.438	0.47	0.827	0.543	0.162	0.282	19	30	24	11	13	17	NEURL1	neuralized E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:7761]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0097440//apical dendrite	"GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0045183//translation factor activity, non-nucleic acid binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity"	GO:0006417//regulation of translation;GO:0006513//protein monoubiquitination;GO:0007219//Notch signaling pathway;GO:0007288//sperm axoneme assembly;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007519//skeletal muscle tissue development;GO:0007595//lactation;GO:0008285//negative regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0030317//flagellated sperm motility;GO:0043065//positive regulation of apoptotic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045746//negative regulation of Notch signaling pathway;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0051491//positive regulation of filopodium assembly;GO:0060999//positive regulation of dendritic spine development;GO:0071230//cellular response to amino acid stimulus;GO:0090129//positive regulation of synapse maturation	--
ENSG00000107957	4.728	4.742	2.605	3.752	4.188	2.685	1128	1137	459	663	844	466	SH3PXD2A	SH3 and PX domains 2A [Source:HGNC Symbol;Acc:HGNC:23664]	-	-	-	-	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0042995//cell projection	"GO:0002020//protease binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding"	GO:0001701//in utero embryonic development;GO:0006801//superoxide metabolic process;GO:0042554//superoxide anion generation;GO:0050790//regulation of catalytic activity;GO:0072593//reactive oxygen species metabolic process;GO:0072675//osteoclast fusion	--
ENSG00000107959	22.264	24.296	21.31	19.85	21.97	22.408	1421	1536	1095	1007	1217	1109	PITRM1	pitrilysin metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:17663]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006626//protein targeting to mitochondrion;GO:0016485//protein processing;GO:0050790//regulation of catalytic activity	--
ENSG00000107960	11.529	11.912	13.081	10.373	8.966	9.216	557	572	420	361	350	366	STN1	STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton;GO:1990879//CST complex"	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0043047//single-stranded telomeric DNA binding	GO:0000723//telomere maintenance;GO:0010833//telomere maintenance via telomere lengthening;GO:0016233//telomere capping;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0045740//positive regulation of DNA replication	--
ENSG00000107968	2.875	2.473	2.239	2.497	3.719	4.904	119	98	94	92	120	121	MAP3K8	mitogen-activated protein kinase kinase kinase 8 [Source:HGNC Symbol;Acc:HGNC:6860]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Immune system;Immune system	ko04010//MAPK signaling pathway;ko04668//TNF signaling pathway;ko04660//T cell receptor signaling pathway;ko04620//Toll-like receptor signaling pathway	K04415;K04415;K04415;K04415	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0031295//T cell costimulation	--
ENSG00000107984	0.828	0.903	0.217	1.082	0.759	1.028	31	34	6	30	24	28	DKK1	dickkopf WNT signaling pathway inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:2891]	Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway	K02165;K02165;K02165	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0039706//co-receptor binding;GO:0048019//receptor antagonist activity;GO:0050750//low-density lipoprotein particle receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000904//cell morphogenesis involved in differentiation;GO:0001706//endoderm formation;GO:0001707//mesoderm formation;GO:0001942//hair follicle development;GO:0002090//regulation of receptor internalization;GO:0007275//multicellular organism development;GO:0007492//endoderm development;GO:0007611//learning or memory;GO:0010628//positive regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0010977//negative regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030279//negative regulation of ossification;GO:0030326//embryonic limb morphogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0032091//negative regulation of protein binding;GO:0032526//response to retinoic acid;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0042663//regulation of endodermal cell fate specification;GO:0043066//negative regulation of apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0045813//positive regulation of Wnt signaling pathway, calcium modulating pathway;GO:0050807//regulation of synapse organization;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060173//limb development;GO:0060323//head morphogenesis;GO:0060325//face morphogenesis;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0061743//motor learning;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0090647//modulation of age-related behavioral decline;GO:0098883//synapse pruning;GO:1901216//positive regulation of neuron death;GO:1901296//negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:1902949//positive regulation of tau-protein kinase activity;GO:1904338//regulation of dopaminergic neuron differentiation;GO:1904723//negative regulation of Wnt-Frizzled-LRP5/6 complex assembly;GO:1904958//positive regulation of midbrain dopaminergic neuron differentiation;GO:1905607//negative regulation of presynapse assembly;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:2000272//negative regulation of signaling receptor activity;GO:2000726//negative regulation of cardiac muscle cell differentiation"	--
ENSG00000108001	0.038	0.03	0	0.019	0.033	0	4	3	0	1	2	0	EBF3	EBF transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:19087]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	COE
ENSG00000108010	17.805	17.479	17.215	15.546	17.487	19.484	520	518	384	348	437	441	GLRX3	glutaredoxin 3 [Source:HGNC Symbol;Acc:HGNC:15987]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0030018//Z disc;GO:0030425//dendrite;GO:1990229//iron-sulfur cluster assembly complex	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0097573//glutathione oxidoreductase activity	GO:0002026//regulation of the force of heart contraction;GO:0006879//cellular iron ion homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0016226//iron-sulfur cluster assembly;GO:0044571//[2Fe-2S] cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000108018	1.107	1.76	0.945	0.502	0.234	0.267	137	161	91	37	24	21	SORCS1	sortilin related VPS10 domain containing receptor 1 [Source:HGNC Symbol;Acc:HGNC:16697]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity	GO:0006892//post-Golgi vesicle-mediated transport;GO:0007218//neuropeptide signaling pathway	--
ENSG00000108021	10.02	6.654	6.28	4.255	4.875	6.027	1604	1158	792	552	687	757	TASOR2	transcription activation suppressor family member 2 [Source:HGNC Symbol;Acc:HGNC:23484]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000108039	26.535	27.125	26.087	25.024	26.007	28.851	1349	1411	989	943	1098	1084	XPNPEP1	X-prolyl aminopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:12822]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0010815//bradykinin catabolic process	--
ENSG00000108055	7.281	5.646	4.835	3.171	4.619	4.608	834	650	409	269	447	384	SMC3	structural maintenance of chromosomes 3 [Source:HGNC Symbol;Acc:HGNC:2468]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04114//Oocyte meiosis;ko04110//Cell cycle	K06669;K06669	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0008278//cohesin complex;GO:0016363//nuclear matrix;GO:0030893//meiotic cohesin complex;GO:0034990//nuclear mitotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex;GO:0097431//mitotic spindle pole"	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0036033//mediator complex binding;GO:0046982//protein heterodimerization activity;GO:0048487//beta-tubulin binding;GO:0061775//cohesin loading activity;GO:0070840//dynein complex binding	GO:0000278//mitotic cell cycle;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0019827//stem cell population maintenance;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0090307//mitotic spindle assembly	--
ENSG00000108061	12.177	9.873	9.805	7.612	8.006	10.156	987	804	587	453	544	598	SHOC2	SHOC2 leucine rich repeat scaffold protein [Source:HGNC Symbol;Acc:HGNC:15454]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K19613	GO:0000164//protein phosphatase type 1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding	GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0046579//positive regulation of Ras protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000108064	8.646	5.239	7.594	7.178	6.845	6.619	636	519	426	398	386	404	TFAM	"transcription factor A, mitochondrial [Source:HGNC Symbol;Acc:HGNC:11741]"	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05016//Huntington disease;ko04371//Apelin signaling pathway	K11830;K11830	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0042645//mitochondrial nucleoid	"GO:0000976//transcription cis-regulatory region binding;GO:0001018//mitochondrial promoter sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0031072//heat shock protein binding;GO:0034246//mitochondrial transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006390//mitochondrial transcription;GO:0006391//transcription initiation from mitochondrial promoter;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0045893//positive regulation of transcription, DNA-templated"	HMG
ENSG00000108091	8.107	7.655	6.839	5.444	6.477	6.56	963	914	600	479	650	567	CCDC6	coiled-coil domain containing 6 [Source:HGNC Symbol;Acc:HGNC:18782]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05216//Thyroid cancer	K09288;K09288	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0042802//identical protein binding	GO:0007010//cytoskeleton organization;GO:0008150//biological_process	--
ENSG00000108094	8.832	8.087	8.317	8.068	7.246	8.786	530	459	355	289	348	376	CUL2	cullin 2 [Source:HGNC Symbol;Acc:HGNC:2552]	Human Diseases;Genetic Information Processing;Environmental Information Processing;Human Diseases	"Cancer: overview;Folding, sorting and degradation;Signal transduction;Cancer: specific types"	ko05200//Pathways in cancer;ko04120//Ubiquitin mediated proteolysis;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K03870;K03870;K03870;K03870	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0030891//VCB complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000108100	20.564	20.937	20.656	19.223	19.454	20.941	1889	1953	1387	1301	1531	1383	CCNY	cyclin Y [Source:HGNC Symbol;Acc:HGNC:23354]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000308//cytoplasmic cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007049//cell cycle;GO:0016055//Wnt signaling pathway;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045859//regulation of protein kinase activity;GO:0051301//cell division;GO:0060828//regulation of canonical Wnt signaling pathway	--
ENSG00000108106	9.635	8.285	15.182	13.021	11.086	12.35	419	442	332	336	400	380	UBE2S	ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10583	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0010997//anaphase-promoting complex binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0010458//exit from mitosis;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0035519//protein K29-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0051301//cell division;GO:0070534//protein K63-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination;GO:1904668//positive regulation of ubiquitin protein ligase activity	--
ENSG00000108107	204.723	223.296	223.227	256.569	230.45	206.909	3754	3903	3063	3447	3547	2958	RPL28	ribosomal protein L28 [Source:HGNC Symbol;Acc:HGNC:10330]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02903;K02903	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0030425//dendrite;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000108175	12.086	11.753	12.207	11.496	12.687	11.242	1909	1866	1424	1345	1693	1292	ZMIZ1	zinc finger MIZ-type containing 1 [Source:HGNC Symbol;Acc:HGNC:16493]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0030374//nuclear receptor coactivator activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding	GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0003007//heart morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007296//vitellogenesis;GO:0007569//cell aging;GO:0021852//pyramidal neuron migration to cerebral cortex;GO:0030521//androgen receptor signaling pathway;GO:0033233//regulation of protein sumoylation;GO:0045582//positive regulation of T cell differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0048589//developmental growth;GO:0048844//artery morphogenesis;GO:0060395//SMAD protein signal transduction;GO:1903508//positive regulation of nucleic acid-templated transcription	zf-MIZ
ENSG00000108176	2.119	1.147	1.417	1.599	1.23	1.248	52	29	26	30	26	23	DNAJC12	DnaJ heat shock protein family (Hsp40) member C12 [Source:HGNC Symbol;Acc:HGNC:28908]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000108179	39.687	37.577	41.225	44.657	41.005	40.433	1708	1664	1322	1418	1459	1258	PPIF	peptidylprolyl isomerase F [Source:HGNC Symbol;Acc:HGNC:9259]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Cardiovascular disease;Signal transduction;Neurodegenerative disease;Infectious disease: parasitic	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05017//Spinocerebellar ataxia;ko05145//Toxoplasmosis	K09565;K09565;K09565;K09565;K09565;K09565;K09565;K09565;K09565;K09565;K09565;K09565	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005757//mitochondrial permeability transition pore complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0042277//peptide binding	"GO:0000413//protein peptidyl-prolyl isomerization;GO:0002931//response to ischemia;GO:0006457//protein folding;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0008637//apoptotic mitochondrial changes;GO:0010849//regulation of proton-transporting ATPase activity, rotational mechanism;GO:0010939//regulation of necrotic cell death;GO:0012501//programmed cell death;GO:0032780//negative regulation of ATPase activity;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0046902//regulation of mitochondrial membrane permeability;GO:0070266//necroptotic process;GO:0070301//cellular response to hydrogen peroxide;GO:0071243//cellular response to arsenic-containing substance;GO:0071277//cellular response to calcium ion;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0090324//negative regulation of oxidative phosphorylation;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:1902686//mitochondrial outer membrane permeabilization involved in programmed cell death;GO:2000276//negative regulation of oxidative phosphorylation uncoupler activity;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000108187	3.153	3.7	3.212	2.721	2.427	2.479	140	176	113	97	100	92	PBLD	phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding	GO:0009058//biosynthetic process;GO:0030277//maintenance of gastrointestinal epithelium;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060392//negative regulation of SMAD protein signal transduction	--
ENSG00000108219	19.604	21.455	25.106	22.261	23.821	25.134	1223	1201	1000	955	1172	1021	TSPAN14	tetraspanin 14 [Source:HGNC Symbol;Acc:HGNC:23303]	-	-	-	-	GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0097197//tetraspanin-enriched microdomain	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0045747//positive regulation of Notch signaling pathway;GO:0051604//protein maturation;GO:0072659//protein localization to plasma membrane	--
ENSG00000108231	1.171	0.689	1.679	2.132	1.066	1.261	38	25	37	31	38	30	LGI1	leucine rich glioma inactivated 1 [Source:HGNC Symbol;Acc:HGNC:6572]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030307//positive regulation of cell growth;GO:0031175//neuron projection development;GO:0050806//positive regulation of synaptic transmission;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane	--
ENSG00000108239	3.241	2.85	3.613	2.471	2.905	3.127	379	335	312	214	287	266	TBC1D12	TBC1 domain family member 12 [Source:HGNC Symbol;Acc:HGNC:29082]	-	-	-	-	GO:0005768//endosome;GO:0005776//autophagosome;GO:0055037//recycling endosome	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity;GO:2000785//regulation of autophagosome assembly	--
ENSG00000108242	0	0	0	0	0	0	0	0	0	0	0	0	CYP2C18	cytochrome P450 family 2 subfamily C member 18 [Source:HGNC Symbol;Acc:HGNC:2620]	Metabolism;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Nervous system;Cancer: overview;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism	K17720;K17720;K17720;K17720	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process	--
ENSG00000108244	0.162	0.217	0.197	0.044	0.115	0.181	5	10	3	1	3	4	KRT23	keratin 23 [Source:HGNC Symbol;Acc:HGNC:6438]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000108255	0.242	0.18	0.082	0.902	0.215	0.332	4	3	1	11	3	4	CRYBA1	crystallin beta A1 [Source:HGNC Symbol;Acc:HGNC:2394]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome	GO:0003674//molecular_function;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0001818//negative regulation of cytokine production;GO:0002088//lens development in camera-type eye;GO:0006909//phagocytosis;GO:0007601//visual perception;GO:0010506//regulation of autophagy;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0032007//negative regulation of TOR signaling;GO:0051898//negative regulation of protein kinase B signaling;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000210//positive regulation of anoikis	--
ENSG00000108256	13.953	11.474	12.063	10.489	10.671	11.301	3148	2602	2010	1632	2034	1800	NUFIP2	nuclear FMR1 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17634]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016604//nuclear body;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000108262	22.84	23.162	26.555	34.388	31.875	35.609	1745	1772	1449	1937	2088	1956	GIT1	GIT ArfGAP 1 [Source:HGNC Symbol;Acc:HGNC:4272]	Cellular Processes;Cellular Processes;Human Diseases	Transport and catabolism;Cell motility;Infectious disease: bacterial	ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K05737;K05737;K05737	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0097431//mitotic spindle pole;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0110165//cellular anatomical entity	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0001957//intramembranous ossification;GO:0007420//brain development;GO:0007626//locomotory behavior;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010646//regulation of cell communication;GO:0023051//regulation of signaling;GO:0032465//regulation of cytokinesis;GO:0032691//negative regulation of interleukin-1 beta production;GO:0045454//cell redox homeostasis;GO:0045820//negative regulation of glycolytic process;GO:0048013//ephrin receptor signaling pathway;GO:0048666//neuron development;GO:0050790//regulation of catalytic activity;GO:0061743//motor learning;GO:0071222//cellular response to lipopolysaccharide;GO:0090063//positive regulation of microtubule nucleation;GO:0099171//presynaptic modulation of chemical synaptic transmission;GO:0106015//negative regulation of inflammatory response to wounding;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000108298	798.752	860.541	807.082	808.625	686.148	670.372	12222	13233	9120	9164	8873	7466	RPL19	ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02885;K02885	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000108306	3.919	4.736	4.563	5.032	4.297	4.344	493	505	375	336	391	350	FBXL20	F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding	"GO:0001662//behavioral fear response;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0099575//regulation of protein catabolic process at presynapse, modulating synaptic transmission;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000108309	0.096	0	0.307	0.155	0.125	0.04	4	0	9	4	4	1	RUNDC3A	RUN domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16984]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0007264//small GTPase mediated signal transduction;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000108312	38.512	39.397	39.416	36.803	37.642	34.708	2547	2667	1960	1882	2198	1711	UBTF	upstream binding transcription factor [Source:HGNC Symbol;Acc:HGNC:12511]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0001165//RNA polymerase I cis-regulatory region sequence-specific DNA binding;GO:0001181//RNA polymerase I general transcription initiation factor activity;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0097110//scaffold protein binding	GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006360//transcription by RNA polymerase I;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0045943//positive regulation of transcription by RNA polymerase I	HMG
ENSG00000108342	0	0	0	0	0	0	0	0	0	0	0	0	CSF3	colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: viral;Signaling molecules and interaction;Immune system;Signal transduction;Immune system;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04657//IL-17 signaling pathway;ko05144//Malaria	K05423;K05423;K05423;K05423;K05423;K05423;K05423	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0071682//endocytic vesicle lumen	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005130//granulocyte colony-stimulating factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0019899//enzyme binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019221//cytokine-mediated signaling pathway;GO:0030838//positive regulation of actin filament polymerization;GO:0030851//granulocyte differentiation;GO:0032092//positive regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045471//response to ethanol;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0071222//cellular response to lipopolysaccharide;GO:0071345//cellular response to cytokine stimulus;GO:1901215//negative regulation of neuron death;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000108344	48.526	46.848	53.131	53.142	51.52	52.774	2161	2097	1746	1753	1931	1710	PSMD3	"proteasome 26S subunit, non-ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9560]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03033;K03033;K03033;K03033;K03033;K03033;K03033;K03033;K03033	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000108349	27.415	28.826	29.59	28.148	28.504	29.996	2212	2324	1755	1656	1927	1761	CASC3	CASC3 exon junction complex subunit [Source:HGNC Symbol;Acc:HGNC:17040]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14323;K14323	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0035145//exon-exon junction complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0071006//U2-type catalytic step 1 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0008298//intracellular mRNA localization;GO:0008380//RNA splicing;GO:0051028//mRNA transport;GO:2000622//regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000108352	2.228	2.4	2.483	3.01	2.673	3.099	125	134	98	140	174	122	RAPGEFL1	Rap guanine nucleotide exchange factor like 1 [Source:HGNC Symbol;Acc:HGNC:17428]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000108370	1.773	2.277	1.572	1.965	1.739	1.649	91	115	60	75	75	62	RGS9	regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004]	Human Diseases;Organismal Systems	Substance dependence;Sensory system	ko05030//Cocaine addiction;ko04744//Phototransduction	K13765;K13765	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0036367//light adaption;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus;GO:1990603//dark adaptation	--
ENSG00000108375	0.294	0.331	0.247	0.305	0.387	0.292	26.45	32	20	18.36	23	22	RNF43	ring finger protein 43 [Source:HGNC Symbol;Acc:HGNC:18505]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K15694	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0030178//negative regulation of Wnt signaling pathway;GO:0038018//Wnt receptor catabolic process;GO:0072089//stem cell proliferation	--
ENSG00000108379	0.983	0.803	1.013	0.931	0.972	1.028	67	55	51	47	56	51	WNT3	Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:1990909//Wnt signalosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0048018//receptor ligand activity	GO:0000902//cell morphogenesis;GO:0001707//mesoderm formation;GO:0007275//multicellular organism development;GO:0007276//gamete generation;GO:0007411//axon guidance;GO:0009948//anterior/posterior axis specification;GO:0009950//dorsal/ventral axis specification;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0044338//canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0044339//canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0045165//cell fate commitment;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048697//positive regulation of collateral sprouting in absence of injury;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050767//regulation of neurogenesis;GO:0060064//Spemann organizer formation at the anterior end of the primitive streak;GO:0060070//canonical Wnt signaling pathway;GO:0060173//limb development;GO:0060174//limb bud formation;GO:0060323//head morphogenesis;GO:0061180//mammary gland epithelium development;GO:0071300//cellular response to retinoic acid;GO:0072089//stem cell proliferation;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1905474//canonical Wnt signaling pathway involved in stem cell proliferation	--
ENSG00000108381	0.942	0.824	1.117	1.284	0.514	1.417	45	37	38	42	19	40	ASPA	aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism;ko00340//Histidine metabolism"	K01437;K01437;K01437	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004046//aminoacylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0019807//aspartoacylase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0006533//aspartate catabolic process;GO:0022010//central nervous system myelination;GO:0048714//positive regulation of oligodendrocyte differentiation	--
ENSG00000108384	6.95	5.785	6.244	6.366	5.258	5.354	125	106	89	90	80	79	RAD51C	RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K10870;K10870	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030054//cell junction;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0033065//Rad51C-XRCC3 complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0048476//Holliday junction resolvase complex	"GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008821//crossover junction endodeoxyribonuclease activity"	GO:0000707//meiotic DNA recombinase assembly;GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007062//sister chromatid cohesion;GO:0007066//female meiosis sister chromatid cohesion;GO:0007131//reciprocal meiotic recombination;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle	--
ENSG00000108387	11.738	13.943	12.457	7.956	9.324	9.308	309	385	237	174	212	198	SEPTIN4	septin 4 [Source:HGNC Symbol;Acc:HGNC:9165]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04210//Apoptosis;ko04215//Apoptosis - multiple species	K16943;K16943	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005940//septin ring;GO:0008021//synaptic vesicle;GO:0015630//microtubule cytoskeleton;GO:0030133//transport vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031105//septin complex;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0032153//cell division site;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0097227//sperm annulus	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0060090//molecular adaptor activity	GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0017157//regulation of exocytosis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0031398//positive regulation of protein ubiquitination;GO:0034613//cellular protein localization;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0048515//spermatid differentiation;GO:0051301//cell division;GO:0061484//hematopoietic stem cell homeostasis;GO:0061640//cytoskeleton-dependent cytokinesis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000108389	12.308	13.853	14.956	12.761	13.462	13.983	1487	1670	1293	1119	1352	1150	MTMR4	myotubularin related protein 4 [Source:HGNC Symbol;Acc:HGNC:7452]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04140//Autophagy - animal;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18082;K18082;K18082;K18082	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019903//protein phosphatase binding;GO:0046872//metal ion binding;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010506//regulation of autophagy;GO:0016311//dephosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0060304//regulation of phosphatidylinositol dephosphorylation	--
ENSG00000108395	16.406	15.048	13.693	12.221	12.566	14.371	1404	1307	900	798	968	889	TRIM37	tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10608	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0016235//aggresome;GO:0035098//ESC/E(Z) complex;GO:0048471//perinuclear region of cytoplasm	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0035518//histone H2A monoubiquitination;GO:0036353//histone H2A-K119 monoubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046600//negative regulation of centriole replication;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:0070842//aggresome assembly"	--
ENSG00000108405	0	0	0.025	0	0	0.05	0	0	1	0	0	2	P2RX1	purinergic receptor P2X 1 [Source:HGNC Symbol;Acc:HGNC:8533]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04611//Platelet activation	K05215;K05215;K05215	GO:0005639//integral component of nuclear inner membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0032991//protein-containing complex;GO:0035579//specific granule membrane;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane	GO:0000166//nucleotide binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0043924//suramin binding;GO:0044877//protein-containing complex binding;GO:0097159//organic cyclic compound binding	"GO:0002554//serotonin secretion by platelet;GO:0003056//regulation of vascular associated smooth muscle contraction;GO:0006811//ion transport;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007320//insemination;GO:0008217//regulation of blood pressure;GO:0010033//response to organic substance;GO:0019228//neuronal action potential;GO:0019229//regulation of vasoconstriction;GO:0030168//platelet activation;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0043270//positive regulation of ion transport;GO:0046513//ceramide biosynthetic process;GO:0051924//regulation of calcium ion transport;GO:0060079//excitatory postsynaptic potential;GO:0098655//cation transmembrane transport;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000108406	32.166	31.153	27.627	21.316	22.161	22.435	2348	2114	1423	1130	1291	1159	DHX40	DEAH-box helicase 40 [Source:HGNC Symbol;Acc:HGNC:18018]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000108417	0	0	0	0	0	0	0	0	0	0	0	0	KRT37	keratin 37 [Source:HGNC Symbol;Acc:HGNC:6455]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000108423	2.143	1.77	1.775	1.481	1.818	1.946	90	79	64	41	64	59	TUBD1	tubulin delta 1 [Source:HGNC Symbol;Acc:HGNC:16811]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0030030//cell projection organization;GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000108424	65.425	63.959	60.831	45.919	47.289	48.236	4554	4198	3034	2235	2691	2492	KPNB1	karyopherin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6400]	Human Diseases;Genetic Information Processing	Cancer: overview;Translation	ko05207//Chemical carcinogenesis - receptor activation;ko03013//Nucleocytoplasmic transport	K14293;K14293	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0035580//specific granule lumen;GO:0042564//NLS-dependent protein nuclear import complex;GO:0070062//extracellular exosome;GO:0071782//endoplasmic reticulum tubular network;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031267//small GTPase binding;GO:0051879//Hsp90 protein binding;GO:0061608//nuclear import signal receptor activity;GO:0061676//importin-alpha family protein binding	GO:0006404//RNA import into nucleus;GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0006610//ribosomal protein import into nucleus;GO:0006886//intracellular protein transport;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0007080//mitotic metaphase plate congression;GO:0015031//protein transport;GO:0030953//astral microtubule organization;GO:0031291//Ran protein signal transduction;GO:0040001//establishment of mitotic spindle localization;GO:0045184//establishment of protein localization;GO:0090307//mitotic spindle assembly	--
ENSG00000108433	17.916	19.066	20.749	20.68	18.421	16.898	1109.86	1196.5	963.43	935.36	991.64	782.35	GOSR2	golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08496	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0031902//late endosome membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion	--
ENSG00000108439	8.937	11.892	10.253	9.249	9.701	9.319	572	642	435	425	506	382	PNPO	pyridoxamine 5'-phosphate oxidase [Source:HGNC Symbol;Acc:HGNC:30260]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00750//Vitamin B6 metabolism	K00275;K00275	GO:0005829//cytosol	"GO:0004733//pyridoxamine-phosphate oxidase activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity"	GO:0006725//cellular aromatic compound metabolic process;GO:0008615//pyridoxine biosynthetic process;GO:0042816//vitamin B6 metabolic process;GO:0042823//pyridoxal phosphate biosynthetic process;GO:1901615//organic hydroxy compound metabolic process	--
ENSG00000108443	12.298	7.641	7.649	6.212	7.48	7.401	1000	681	519	389	517	487	RPS6KB1	ribosomal protein S6 kinase B1 [Source:HGNC Symbol;Acc:HGNC:10436]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Immune system;Cancer: specific types;Signal transduction;Transport and catabolism;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Cancer: overview;Drug resistance: antineoplastic;Cancer: overview;Signal transduction;Aging;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Aging	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05131//Shigellosis;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko05231//Choline metabolism in cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04350//TGF-beta signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species	K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030165//PDZ domain binding;GO:0042277//peptide binding;GO:0042802//identical protein binding;GO:0051721//protein phosphatase 2A binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0001662//behavioral fear response;GO:0003009//skeletal muscle contraction;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007281//germ cell development;GO:0007568//aging;GO:0007584//response to nutrient;GO:0007616//long-term memory;GO:0009408//response to heat;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009612//response to mechanical stimulus;GO:0009636//response to toxic substance;GO:0009749//response to glucose;GO:0010033//response to organic substance;GO:0010243//response to organonitrogen compound;GO:0014070//response to organic cyclic compound;GO:0014732//skeletal muscle atrophy;GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0031667//response to nutrient levels;GO:0031929//TOR signaling;GO:0032496//response to lipopolysaccharide;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0032870//cellular response to hormone stimulus;GO:0033574//response to testosterone;GO:0033762//response to glucagon;GO:0034612//response to tumor necrosis factor;GO:0043066//negative regulation of apoptotic process;GO:0043200//response to amino acid;GO:0043201//response to leucine;GO:0043434//response to peptide hormone;GO:0043491//protein kinase B signaling;GO:0044539//long-chain fatty acid import into cell;GO:0045471//response to ethanol;GO:0045727//positive regulation of translation;GO:0045931//positive regulation of mitotic cell cycle;GO:0045948//positive regulation of translational initiation;GO:0046324//regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051384//response to glucocorticoid;GO:0071346//cellular response to interferon-gamma;GO:0071363//cellular response to growth factor stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071549//cellular response to dexamethasone stimulus;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000108465	23.245	25.87	29.357	28.024	26.279	27.653	737	830	705	723	691	598	CDK5RAP3	CDK5 regulatory subunit associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18673]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030332//cyclin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0051019//mitogen-activated protein kinase binding;GO:0051059//NF-kappaB binding;GO:0097371//MDM2/MDM4 family protein binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001889//liver development;GO:0001933//negative regulation of protein phosphorylation;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007346//regulation of mitotic cell cycle;GO:0007420//brain development;GO:0008283//cell population proliferation;GO:0010921//regulation of phosphatase activity;GO:0030262//apoptotic nuclear changes;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034976//response to endoplasmic reticulum stress;GO:0043407//negative regulation of MAP kinase activity;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045664//regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060318//definitive erythrocyte differentiation;GO:0071569//protein ufmylation;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:1900182//positive regulation of protein localization to nucleus;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1903363//negative regulation of cellular protein catabolic process	--
ENSG00000108468	43.093	42.553	45.878	35.441	35.086	40.334	1952	1938	1501	1190	1343	1333	CBX1	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005819//spindle;GO:0010369//chromocenter;GO:0090734//site of DNA damage"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:1990226//histone methyltransferase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000108469	10.33	10.725	10.495	9.999	10.992	10.26	525	610	420	439	498	429	RECQL5	RecQ like helicase 5 [Source:HGNC Symbol;Acc:HGNC:9950]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016591//RNA polymerase II, holoenzyme"	GO:0000166//nucleotide binding;GO:0000993//RNA polymerase II complex binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0043138//3'-5' DNA helicase activity	GO:0000278//mitotic cell cycle;GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0032508//DNA duplex unwinding;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0051301//cell division;GO:0051304//chromosome separation;GO:0071466//cellular response to xenobiotic stimulus;GO:0072757//cellular response to camptothecin;GO:1990414//replication-born double-strand break repair via sister chromatid exchange;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000108474	1.482	1.671	1.647	1.258	2.481	2.094	33	41	29	19.92	45	36	PIGL	phosphatidylinositol glycan anchor biosynthesis class L [Source:HGNC Symbol;Acc:HGNC:8966]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03434;K03434	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000225//N-acetylglucosaminylphosphatidylinositol deacetylase activity;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"	GO:0006506//GPI anchor biosynthetic process;GO:0006629//lipid metabolic process;GO:0016254//preassembly of GPI anchor in ER membrane	--
ENSG00000108479	15.705	16.923	17.327	18.751	16.196	18.911	453	499	375	402	401	401	GALK1	galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00052//Galactose metabolism	K00849;K00849;K00849	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004335//galactokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005534//galactose binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0006012//galactose metabolic process;GO:0016310//phosphorylation;GO:0019388//galactose catabolic process;GO:0019402//galactitol metabolic process;GO:0044238//primary metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0061623//glycolytic process from galactose;GO:0071704//organic substance metabolic process	--
ENSG00000108506	2.096	1.63	1.905	1.349	1.831	1.842	259	202	171	127	190	168	INTS2	integrator complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:29241]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing	--
ENSG00000108509	5.993	7.209	7.033	8.398	7.5	7.022	553	591	479	554	585	472	CAMTA2	calmodulin binding transcription activator 2 [Source:HGNC Symbol;Acc:HGNC:18807]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051171//regulation of nitrogen compound metabolic process;GO:0060255//regulation of macromolecule metabolic process;GO:0080090//regulation of primary metabolic process	CG-1
ENSG00000108510	10.551	7.687	8.374	6.255	6.781	6.562	1943	1581	1185	755	1047	1036	MED13	mediator complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:22474]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15164	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0042632//cholesterol homeostasis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0070328//triglyceride homeostasis"	--
ENSG00000108511	0.049	0.029	0	0	0	0	2	1	0	0	0	0	HOXB6	homeobox B6 [Source:HGNC Symbol;Acc:HGNC:5117]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0034101//erythrocyte homeostasis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000108515	1.481	0.622	1.205	0.61	1.171	1.426	27	17	24	13	21	25	ENO3	enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354]	Metabolism;Environmental Information Processing;Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Signal transduction;Global and overview maps;Folding, sorting and degradation;Global and overview maps;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K01689;K01689;K01689;K01689;K01689;K01689	GO:0000015//phosphopyruvate hydratase complex;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0004634//phosphopyruvate hydratase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding	GO:0006096//glycolytic process;GO:0021762//substantia nigra development	--
ENSG00000108518	241.804	258.813	266.227	298.666	289.806	282.243	3821	4065	3052	3433	3786	3201	PFN1	profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway	K05759;K05759;K05759;K05759;K05759	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098978//glutamatergic synapse	"GO:0000774//adenyl-nucleotide exchange factor activity;GO:0001784//phosphotyrosine residue binding;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding;GO:0070064//proline-rich region binding"	GO:0001843//neural tube closure;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010634//positive regulation of epithelial cell migration;GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0032232//negative regulation of actin filament bundle assembly;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032781//positive regulation of ATPase activity;GO:0050821//protein stabilization;GO:0051497//negative regulation of stress fiber assembly;GO:0060074//synapse maturation;GO:0098885//modification of postsynaptic actin cytoskeleton;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000108523	49.935	50.709	55.277	60.133	57.751	55.405	1750	1787	1398	1534	1715	1417	RNF167	ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544]	-	-	-	-	GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0045786//negative regulation of cell cycle	--
ENSG00000108528	60.594	60.177	70.469	73.944	71.81	66.545	1792	1775	1529	1629	1760	1391	SLC25A11	solute carrier family 25 member 11 [Source:HGNC Symbol;Acc:HGNC:10981]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015116//sulfate transmembrane transporter activity;GO:0015117//thiosulfate transmembrane transporter activity;GO:0015131//oxaloacetate transmembrane transporter activity;GO:0015140//malate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015367//oxoglutarate:malate antiporter activity	GO:0008272//sulfate transport;GO:0015709//thiosulfate transport;GO:0015729//oxaloacetate transport;GO:0015742//alpha-ketoglutarate transport;GO:0035435//phosphate ion transmembrane transport;GO:0071422//succinate transmembrane transport;GO:0071423//malate transmembrane transport;GO:1902356//oxaloacetate(2-) transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000108551	0.034	0.362	0.093	0.474	0.17	0.493	1	13	2	11	5	11	RASD1	ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828]	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Environmental adaptation	ko04934//Cushing syndrome;ko04713//Circadian entrainment	K07843;K07843	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007263//nitric oxide mediated signal transduction;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000108556	0.063	0.063	0	0	0.05	0.058	3	3	0	0	2	2	CHRNE	cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04817	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0008324//cation transmembrane transporter activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0098655//cation transmembrane transport"	--
ENSG00000108557	15.772	14.013	18.14	15.324	18.08	16.584	2275	2128	1855	1747	2236	1871	RAI1	retinoic acid induced 1 [Source:HGNC Symbol;Acc:HGNC:9834]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001501//skeletal system development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032922//circadian regulation of gene expression;GO:0040015//negative regulation of multicellular organism growth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000108559	10.295	9.234	8.471	6.64	5.815	6.717	665.8	665.04	464.83	336.38	356.03	366.05	NUP88	nucleoporin 88 [Source:HGNC Symbol;Acc:HGNC:8067]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14318;K14318	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005215//transporter activity;GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0000055//ribosomal large subunit export from nucleus;GO:0000056//ribosomal small subunit export from nucleus;GO:0000278//mitotic cell cycle;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000108561	98.255	98.678	106.648	107.534	95.533	101.308	2374	2385	1811	1926	1950	1742	C1QBP	complement C1q binding protein [Source:HGNC Symbol;Acc:HGNC:1243]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0048786//presynaptic active zone;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0001849//complement component C1q complex binding;GO:0003714//transcription corepressor activity;GO:0003729//mRNA binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0008134//transcription factor binding;GO:0030984//kininogen binding;GO:0031690//adrenergic receptor binding;GO:0097177//mitochondrial ribosome binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0008380//RNA splicing;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0030449//regulation of complement activation;GO:0032689//negative regulation of interferon-gamma production;GO:0032695//negative regulation of interleukin-12 production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0042254//ribosome biogenesis;GO:0042256//mature ribosome assembly;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0045785//positive regulation of cell adhesion;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0050687//negative regulation of defense response to virus;GO:0051897//positive regulation of protein kinase B signaling;GO:0070131//positive regulation of mitochondrial translation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901165//positive regulation of trophoblast cell migration;GO:2000510//positive regulation of dendritic cell chemotaxis"	--
ENSG00000108576	0.015	0	0	0	0	0.065	2	0	0	0	0	3	SLC6A4	solute carrier family 6 member 4 [Source:HGNC Symbol;Acc:HGNC:11050]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04726//Serotonergic synapse;ko04721//Synaptic vesicle cycle	K05037;K05037	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0045202//synapse;GO:0098793//presynapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0099154//serotonergic synapse	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005335//serotonin:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0015293//symporter activity;GO:0017075//syntaxin-1 binding;GO:0019811//cocaine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050998//nitric-oxide synthase binding;GO:0051015//actin filament binding;GO:0051378//serotonin binding	"GO:0001666//response to hypoxia;GO:0006836//neurotransmitter transport;GO:0006837//serotonin transport;GO:0007420//brain development;GO:0007584//response to nutrient;GO:0007613//memory;GO:0007623//circadian rhythm;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010033//response to organic substance;GO:0010628//positive regulation of gene expression;GO:0014064//positive regulation of serotonin secretion;GO:0015844//monoamine transport;GO:0021941//negative regulation of cerebellar granule cell precursor proliferation;GO:0032227//negative regulation of synaptic transmission, dopaminergic;GO:0032355//response to estradiol;GO:0035176//social behavior;GO:0035725//sodium ion transmembrane transport;GO:0042310//vasoconstriction;GO:0042713//sperm ejaculation;GO:0045665//negative regulation of neuron differentiation;GO:0045787//positive regulation of cell cycle;GO:0046621//negative regulation of organ growth;GO:0048854//brain morphogenesis;GO:0051610//serotonin uptake;GO:0055085//transmembrane transport;GO:0071300//cellular response to retinoic acid;GO:0071310//cellular response to organic substance;GO:0071321//cellular response to cGMP;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0090067//regulation of thalamus size;GO:0098810//neurotransmitter reuptake"	--
ENSG00000108578	18.932	19.131	17.553	19.477	17.562	16.683	864	854	552	615	654	517	BLMH	bleomycin hydrolase [Source:HGNC Symbol;Acc:HGNC:1059]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0000209//protein polyubiquitination;GO:0006508//proteolysis;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0043418//homocysteine catabolic process	--
ENSG00000108582	17.239	16.445	14.141	11.005	14.166	12.447	2647	2593	1608	1358	1812	1465	CPD	carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0016485//protein processing	--
ENSG00000108587	14.176	15.106	16.074	14.201	14.984	13.278	958.44	1007.75	777.62	710.31	859.24	637.61	GOSR1	golgi SNAP receptor complex member 1 [Source:HGNC Symbol;Acc:HGNC:4430]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08495	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031201//SNARE complex;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000108588	47.49	44.327	41.086	39.141	41.822	45.886	2391	2403	1629	1536	1825	1710	CCDC47	coiled-coil domain containing 47 [Source:HGNC Symbol;Acc:HGNC:24856]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030867//rough endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0044183//protein folding chaperone	GO:0001649//osteoblast differentiation;GO:0006457//protein folding;GO:0006983//ER overload response;GO:0007029//endoplasmic reticulum organization;GO:0009791//post-embryonic development;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0036503//ERAD pathway;GO:0045048//protein insertion into ER membrane;GO:0055074//calcium ion homeostasis	--
ENSG00000108590	7.186	6.067	6.935	5.903	6.763	8.358	141.34	132.42	91.75	79.82	99.12	93.24	MED31	mediator complex subunit 31 [Source:HGNC Symbol;Acc:HGNC:24260]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0048147//negative regulation of fibroblast proliferation;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060173//limb development;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000108591	19.767	23.681	23.851	22.857	22.516	19.229	765	914	677	658	735	525	DRG2	developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0002181//cytoplasmic translation;GO:0007165//signal transduction	--
ENSG00000108592	14.853	14.966	16.279	13.27	15.511	14.094	1075	1108	840	724	871	727	FTSJ3	FtsJ RNA 2'-O-methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17136]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0030688//preribosome, small subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0008650//rRNA (uridine-2'-O-)-methyltransferase activity;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0016740//transferase activity;GO:0062105//RNA 2'-O-methyltransferase activity	"GO:0000453//enzyme-directed rRNA 2'-O-methylation;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0042254//ribosome biogenesis;GO:0043414//macromolecule methylation"	--
ENSG00000108599	12.434	11.204	9.85	9.545	9.296	10.524	785	677	507	467	543	545	AKAP10	A-kinase anchoring protein 10 [Source:HGNC Symbol;Acc:HGNC:368]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0051018//protein kinase A binding	GO:0007165//signal transduction;GO:0008104//protein localization;GO:0016310//phosphorylation	--
ENSG00000108602	0.421	0.354	1.205	0.201	0.627	0.264	10	12	19	5	18	7	ALDH3A1	aldehyde dehydrogenase 3 family member A1 [Source:HGNC Symbol;Acc:HGNC:405]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Xenobiotics biodegradation and metabolism;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00982//Drug metabolism - cytochrome P450;ko00350//Tyrosine metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism;ko00360//Phenylalanine metabolism	K00129;K00129;K00129;K00129;K00129;K00129;K00129;K00129	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016021//integral component of membrane	"GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0005515//protein binding;GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0018479//benzaldehyde dehydrogenase (NAD+) activity"	GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000108604	16.082	15.742	17.001	20.226	20.219	17.009	714	719	561	605	703	521	SMARCD2	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 [Source:HGNC Symbol;Acc:HGNC:11107]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11650;K11650	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0140092//bBAF complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding	"GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000108622	0	0.087	0.186	0	0	0.118	0	1.92	2.54	0	0	2	ICAM2	intercellular adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:5345]	Organismal Systems;Environmental Information Processing	Immune system;Signaling molecules and interaction	ko04650//Natural killer cell mediated cytotoxicity;ko04514//Cell adhesion molecules	K06523;K06523	GO:0001931//uropod;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0071944//cell periphery	GO:0005178//integrin binding	GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000108639	72.192	74.051	70.287	83.171	78.909	82.371	2263	2309	1607	1909	2096	1860	SYNGR2	synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499]	-	-	-	-	GO:0005811//lipid droplet;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0045055//regulated exocytosis;GO:0048499//synaptic vesicle membrane organization	--
ENSG00000108641	25.2	25.28	23.239	27.166	24.653	21.074	479.48	494.72	347.18	375.85	391.67	279.72	B9D1	B9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24123]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008158//hedgehog receptor activity	GO:0001701//in utero embryonic development;GO:0001944//vasculature development;GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0032880//regulation of protein localization;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0060271//cilium assembly;GO:0060563//neuroepithelial cell differentiation	--
ENSG00000108651	5.812	5.807	5.918	4.359	4.297	6.494	522	435	332	290	306	272	UTP6	UTP6 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:18279]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14557	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0034388//Pwp2p-containing subcomplex of 90S preribosome	GO:0005515//protein binding;GO:0030515//snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006396//RNA processing"	--
ENSG00000108654	291.45	272.172	297.794	227.372	266.652	292.759	10334	9283	7559	6124	7478	7408	DDX5	DEAD-box helicase 5 [Source:HGNC Symbol;Acc:HGNC:2746]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Cancer: overview;Transcription	ko05202//Transcriptional misregulation in cancer;ko05205//Proteoglycans in cancer;ko03040//Spliceosome	K12823;K12823;K12823	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003730//mRNA 3'-UTR binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035500//MH2 domain binding;GO:0036002//pre-mRNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0046332//SMAD binding;GO:0050681//androgen receptor binding;GO:0070412//R-SMAD binding;GO:0070878//primary miRNA binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001837//epithelial to mesenchymal transition;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0009299//mRNA transcription;GO:0030509//BMP signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045445//myoblast differentiation;GO:0045667//regulation of osteoblast differentiation;GO:0048511//rhythmic process;GO:0060765//regulation of androgen receptor signaling pathway;GO:0061614//pri-miRNA transcription by RNA polymerase II;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:2001014//regulation of skeletal muscle cell differentiation"	--
ENSG00000108666	7.535	6.195	8.328	7.237	7.065	7.015	363	388	273	239	304	253	C17orf75	chromosome 17 open reading frame 75 [Source:HGNC Symbol;Acc:HGNC:30173]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0099041//vesicle tethering to Golgi	--
ENSG00000108669	10.225	8.558	9.395	10.493	8.93	13.142	614	459	407	418	474	497	CYTH1	cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway	K18441;K18441;K18441;K18441;K18441	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0016192//vesicle-mediated transport;GO:0030155//regulation of cell adhesion;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0090162//establishment of epithelial cell polarity	--
ENSG00000108671	19.013	20.381	22.262	18.382	19.572	20.764	1193	1224	974	870	1008	934	PSMD11	"proteasome 26S subunit, non-ATPase 11 [Source:HGNC Symbol;Acc:HGNC:9556]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03036;K03036;K03036;K03036;K03036;K03036;K03036;K03036;K03036	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen"	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043248//proteasome assembly;GO:0048863//stem cell differentiation	--
ENSG00000108679	734.278	807.066	833.411	829.889	879.499	823.798	31100	34413	25880	26081	31270	25475	LGALS3BP	galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005044//scavenger receptor activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0006968//cellular defense response;GO:0007155//cell adhesion;GO:0007165//signal transduction	--
ENSG00000108684	1.08	1.036	1.41	2.187	2.45	1.979	84	81	81	126	161	112	ASIC2	acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99]	Organismal Systems;Organismal Systems	Sensory system;Sensory system	ko04750//Inflammatory mediator regulation of TRP channels;ko04742//Taste transduction	K04828;K04828	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0022839//ion gated channel activity	GO:0003026//regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0007268//chemical synaptic transmission;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0007602//phototransduction;GO:0007605//sensory perception of sound;GO:0009612//response to mechanical stimulus;GO:0010447//response to acidic pH;GO:0019229//regulation of vasoconstriction;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035418//protein localization to synapse;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043066//negative regulation of apoptotic process;GO:0050915//sensory perception of sour taste;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0051965//positive regulation of synapse assembly;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000108688	0	0	0	0	0	0	0	0	0	0	0	0	CCL7	C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway	K05509;K05509;K05509;K05509	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0031726//CCR1 chemokine receptor binding;GO:0031727//CCR2 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:2000503//positive regulation of natural killer cell chemotaxis	--
ENSG00000108691	26.485	26.403	31.456	25.52	22.713	41.427	408	410	358	293	297	467	CCL2	C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Immune system;Infectious disease: viral;Immune disease;Cardiovascular disease;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Signaling molecules and interaction;Immune system;Infectious disease: parasitic	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05323//Rheumatoid arthritis;ko05418//Fluid shear stress and atherosclerosis;ko04668//TNF signaling pathway;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05144//Malaria	K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624;K14624	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004672//protein kinase activity;GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031727//CCR2 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	"GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008360//regulation of cell shape;GO:0009617//response to bacterium;GO:0009887//animal organ morphogenesis;GO:0019079//viral genome replication;GO:0019221//cytokine-mediated signaling pathway;GO:0019233//sensory perception of pain;GO:0019725//cellular homeostasis;GO:0030593//neutrophil chemotaxis;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0034351//negative regulation of glial cell apoptotic process;GO:0035684//helper T cell extravasation;GO:0043491//protein kinase B signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0043615//astrocyte cell migration;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0048245//eosinophil chemotaxis;GO:0048246//macrophage chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050870//positive regulation of T cell activation;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0090280//positive regulation of calcium ion import;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:1905563//negative regulation of vascular endothelial cell proliferation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000427//positive regulation of apoptotic cell clearance;GO:2000502//negative regulation of natural killer cell chemotaxis"	--
ENSG00000108700	0	0	0	0.076	0	0	0	0	0	1	0	0	CCL8	C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K16596;K16596;K16596	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004672//protein kinase activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0016004//phospholipase activator activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0002687//positive regulation of leukocyte migration;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0044828//negative regulation by host of viral genome replication;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070664//negative regulation of leukocyte proliferation;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000108702	0	0	0	0	0	0	0	0	0	0	0	0	CCL1	C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05514;K05514;K05514	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016032//viral process;GO:0030593//neutrophil chemotaxis;GO:0032740//positive regulation of interleukin-17 production;GO:0043547//positive regulation of GTPase activity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000108733	7.391	7.533	6.863	5.695	6.126	7.511	370	393	269	229	269	273	PEX12	peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13345	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990429//peroxisomal importomer complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006513//protein monoubiquitination;GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix	--
ENSG00000108759	0.024	0	0	0	0.028	0	1	0	0	0	1	0	KRT32	keratin 32 [Source:HGNC Symbol;Acc:HGNC:6449]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000108771	1.187	1.061	1.348	0.981	0.992	0.665	56	50	50	35	43	26	DHX58	DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12649	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0009615//response to virus;GO:0009617//response to bacterium;GO:0032480//negative regulation of type I interferon production;GO:0032481//positive regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0045824//negative regulation of innate immune response;GO:0051607//defense response to virus;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000108773	4.852	5.783	6.488	7.421	8.638	7.859	309	370	306	352	433	361	KAT2A	lysine acetyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:4201]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Endocrine system;Signal transduction	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04919//Thyroid hormone signaling pathway;ko04330//Notch signaling pathway	K06062;K06062;K06062;K06062	GO:0000123//histone acetyltransferase complex;GO:0000124//SAGA complex;GO:0000785//chromatin;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0033276//transcription factor TFTC complex;GO:0045252//oxoglutarate dehydrogenase complex;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0010484//H3 histone acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019903//protein phosphatase binding;GO:0042826//histone deacetylase binding;GO:0043997//histone acetyltransferase activity (H4-K12 specific);GO:0061733//peptide-lysine-N-acetyltransferase activity;GO:0106078//histone succinyltransferase activity;GO:0106228//peptide glutaryltransferase activity;GO:0106229//histone glutaryltransferase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001819//positive regulation of cytokine production;GO:0001843//neural tube closure;GO:0006282//regulation of DNA repair;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007507//heart development;GO:0007616//long-term memory;GO:0008283//cell population proliferation;GO:0014070//response to organic cyclic compound;GO:0016573//histone acetylation;GO:0016578//histone deubiquitination;GO:0018393//internal peptidyl-lysine acetylation;GO:0021537//telencephalon development;GO:0022037//metencephalon development;GO:0030901//midbrain development;GO:0031063//regulation of histone deacetylation;GO:0031346//positive regulation of cell projection organization;GO:0031647//regulation of protein stability;GO:0031667//response to nutrient levels;GO:0035066//positive regulation of histone acetylation;GO:0035264//multicellular organism growth;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045589//regulation of regulatory T cell differentiation;GO:0045722//positive regulation of gluconeogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0046600//negative regulation of centriole replication;GO:0048167//regulation of synaptic plasticity;GO:0048312//intracellular distribution of mitochondria;GO:0050863//regulation of T cell activation;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0060173//limb development;GO:0061035//regulation of cartilage development;GO:0071356//cellular response to tumor necrosis factor;GO:0071929//alpha-tubulin acetylation;GO:0090043//regulation of tubulin deacetylation;GO:0106077//histone succinylation;GO:0106227//peptidyl-lysine glutarylation;GO:1903010//regulation of bone development;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000036//regulation of stem cell population maintenance;GO:2000727//positive regulation of cardiac muscle cell differentiation"	--
ENSG00000108774	73.513	79.21	80.659	83.07	80.038	79.447	2458	2697	1973	2044	2242	1929	RAB5C	"RAB5C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9785]"	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Infectious disease: parasitic;Excretory system	ko05132//Salmonella infection;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko04145//Phagosome;ko05146//Amoebiasis;ko04962//Vasopressin-regulated water reabsorption	K07889;K07889;K07889;K07889;K07889;K07889;K07889	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0031901//early endosome membrane;GO:0035577//azurophil granule membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0048227//plasma membrane to endosome transport	--
ENSG00000108784	60.464	62.744	66.046	82.361	78.637	74.958	2897	3051	2411	2936	3174	2653	NAGLU	N-acetyl-alpha-glucosaminidase [Source:HGNC Symbol;Acc:HGNC:7632]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01205;K01205;K01205	GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0004561//alpha-N-acetylglucosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0006027//glycosaminoglycan catabolic process;GO:0007040//lysosome organization;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0021680//cerebellar Purkinje cell layer development;GO:0042474//middle ear morphogenesis;GO:0045475//locomotor rhythm;GO:0046548//retinal rod cell development;GO:0060119//inner ear receptor cell development;GO:1901135//carbohydrate derivative metabolic process	--
ENSG00000108786	0.65	0.717	0.823	1.383	1.263	0.629	15	19	16	27	28	12	HSD17B1	hydroxysteroid 17-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5210]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K00044;K00044;K00044	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0042803//protein homodimerization activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0050661//NADP binding;GO:0070401//NADP+ binding;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:1903924//estradiol binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008210//estrogen metabolic process;GO:0060348//bone development;GO:0061370//testosterone biosynthetic process;GO:0071248//cellular response to metal ion	--
ENSG00000108788	12.039	13.712	16.067	14.066	13.261	14.319	591.54	677.56	581.71	496.69	548.38	512.35	MLX	MAX dimerization protein MLX [Source:HGNC Symbol;Acc:HGNC:11645]	Human Diseases;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease	ko04932//Non-alcoholic fatty liver disease;ko04931//Insulin resistance	K09113;K09113	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000108797	4.309	4.835	5.746	4.385	5.163	4.417	480	553	475	351	501	356.94	CNTNAP1	contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07379	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0033010//paranodal junction;GO:0033270//paranode region of axon;GO:0048787//presynaptic active zone membrane	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0038023//signaling receptor activity	"GO:0002175//protein localization to paranode region of axon;GO:0007005//mitochondrion organization;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0019227//neuronal action potential propagation;GO:0022010//central nervous system myelination;GO:0022011//myelination in peripheral nervous system;GO:0030913//paranodal junction assembly;GO:0031175//neuron projection development;GO:0042552//myelination;GO:0048812//neuron projection morphogenesis;GO:0050884//neuromuscular process controlling posture;GO:0050885//neuromuscular process controlling balance;GO:0050905//neuromuscular process;GO:0071205//protein localization to juxtaparanode region of axon;GO:0097106//postsynaptic density organization;GO:0098529//neuromuscular junction development, skeletal muscle fiber;GO:1990227//paranodal junction maintenance"	--
ENSG00000108798	0	0	0.12	0	0.035	0	0	0	3	0	1	0	ABI3	ABI family member 3 [Source:HGNC Symbol;Acc:HGNC:29859]	-	-	-	-	GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0042802//identical protein binding;GO:0051015//actin filament binding	GO:0002357//defense response to tumor cell;GO:0010593//negative regulation of lamellipodium assembly;GO:0030334//regulation of cell migration;GO:0061001//regulation of dendritic spine morphogenesis;GO:0099151//regulation of postsynaptic density assembly;GO:1900028//negative regulation of ruffle assembly;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000774//positive regulation of cellular senescence	--
ENSG00000108799	5.28	3.964	4.996	5.781	5.725	4.694	433	361	305	348	364	276	EZH1	enhancer of zeste 1 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3526]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K17451;K17451	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex"	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0031493//nucleosomal histone binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0009653//anatomical structure morphogenesis;GO:0021766//hippocampus development;GO:0031507//heterochromatin assembly;GO:0031509//subtelomeric heterochromatin assembly;GO:0032259//methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070734//histone H3-K27 methylation	--
ENSG00000108813	0.289	0.157	0.186	0.203	0.132	0.131	11	5	4	6	4	4	DLX4	distal-less homeobox 4 [Source:HGNC Symbol;Acc:HGNC:2917]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	Homeobox
ENSG00000108819	19.23	18.858	21.542	18.419	18.466	19.051	1680	1656	1390	1192	1363	1211	PPP1R9B	protein phosphatase 1 regulatory subunit 9B [Source:HGNC Symbol;Acc:HGNC:9298]	-	-	-	-	GO:0000164//protein phosphatase type 1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030864//cortical actin cytoskeleton;GO:0032587//ruffle membrane;GO:0032591//dendritic spine membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044326//dendritic spine neck;GO:0044327//dendritic spine head;GO:0045202//synapse;GO:1990780//cytoplasmic side of dendritic spine plasma membrane	GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008157//protein phosphatase 1 binding;GO:0019900//kinase binding;GO:0031749//D2 dopamine receptor binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding	GO:0001560//regulation of cell growth by extracellular stimulus;GO:0001932//regulation of protein phosphorylation;GO:0001975//response to amphetamine;GO:0003006//developmental process involved in reproduction;GO:0006468//protein phosphorylation;GO:0007015//actin filament organization;GO:0007096//regulation of exit from mitosis;GO:0007399//nervous system development;GO:0007568//aging;GO:0007612//learning;GO:0008380//RNA splicing;GO:0009410//response to xenobiotic stimulus;GO:0010243//response to organonitrogen compound;GO:0014070//response to organic cyclic compound;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0019722//calcium-mediated signaling;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030042//actin filament depolymerization;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0031175//neuron projection development;GO:0032355//response to estradiol;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0034695//response to prostaglandin E;GO:0035094//response to nicotine;GO:0035902//response to immobilization stress;GO:0042127//regulation of cell population proliferation;GO:0043200//response to amino acid;GO:0046847//filopodium assembly;GO:0048545//response to steroid hormone;GO:0050804//modulation of chemical synaptic transmission;GO:0051726//regulation of cell cycle;GO:0060179//male mating behavior;GO:0061458//reproductive system development;GO:0071315//cellular response to morphine;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071466//cellular response to xenobiotic stimulus;GO:0097338//response to clozapine;GO:1901653//cellular response to peptide;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903119//protein localization to actin cytoskeleton;GO:1903829//positive regulation of cellular protein localization;GO:1904372//positive regulation of protein localization to actin cortical patch;GO:1904373//response to kainic acid;GO:1904386//response to L-phenylalanine derivative;GO:1990778//protein localization to cell periphery;GO:2000474//regulation of opioid receptor signaling pathway	--
ENSG00000108821	227.967	251.565	105.133	70.311	106.45	43.162	27084	29986	8748	5980	10458	3683	COL1A1	collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Immune system;Digestive system;Endocrine and metabolic disease;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04512//ECM-receptor interaction	K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005584//collagen type I trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0030141//secretory granule;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0002020//protease binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048407//platelet-derived growth factor binding	"GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001568//blood vessel development;GO:0001649//osteoblast differentiation;GO:0001957//intramembranous ossification;GO:0001958//endochondral ossification;GO:0007584//response to nutrient;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010812//negative regulation of cell-substrate adhesion;GO:0015031//protein transport;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030335//positive regulation of cell migration;GO:0031667//response to nutrient levels;GO:0031960//response to corticosteroid;GO:0032355//response to estradiol;GO:0032964//collagen biosynthetic process;GO:0034504//protein localization to nucleus;GO:0034505//tooth mineralization;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0042060//wound healing;GO:0042542//response to hydrogen peroxide;GO:0043434//response to peptide hormone;GO:0043588//skin development;GO:0043589//skin morphogenesis;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0044691//tooth eruption;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048545//response to steroid hormone;GO:0048705//skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0051591//response to cAMP;GO:0055093//response to hyperoxia;GO:0060325//face morphogenesis;GO:0060346//bone trabecula formation;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0071300//cellular response to retinoic acid;GO:0071306//cellular response to vitamin E;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902617//response to fluoride;GO:1902618//cellular response to fluoride"	--
ENSG00000108823	0.511	0.635	0.616	0	0.23	0.063	14	17	11	0	5	1	SGCA	sarcoglycan alpha [Source:HGNC Symbol;Acc:HGNC:10805]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12565;K12565;K12565;K12565	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016011//dystroglycan complex;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0045121//membrane raft	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0043403//skeletal muscle tissue regeneration	--
ENSG00000108825	0.427	0.637	0.632	0.225	0.197	0.064	19.03	27.24	11.24	7.3	7.43	1.97	PTGES3L-AARSD1	PTGES3L-AARSD1 readthrough [Source:HGNC Symbol;Acc:HGNC:43946]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000166//nucleotide binding;GO:0002196//Ser-tRNA(Ala) hydrolase activity;GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004813//alanine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:0140101//catalytic activity, acting on a tRNA"	GO:0006399//tRNA metabolic process;GO:0006412//translation;GO:0006419//alanyl-tRNA aminoacylation;GO:0006450//regulation of translational fidelity;GO:0008150//biological_process;GO:0043039//tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000108826	17.879	20.599	22.146	22.447	19.201	24.532	281	324	252	258	265	281	MRPL27	mitochondrial ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:14483]	Genetic Information Processing	Translation	ko03010//Ribosome	K02899	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000108828	153.537	161.993	167.444	194.333	175.186	179.825	8558	9060	6899	8008	8173	7276	VAT1	vesicle amine transport 1 [Source:HGNC Symbol;Acc:HGNC:16919]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity	GO:0010637//negative regulation of mitochondrial fusion	--
ENSG00000108829	18.782	16.804	18.677	17.288	18.368	13.389	1121.96	1007.98	824	764.97	926	581.94	LRRC59	leucine rich repeat containing 59 [Source:HGNC Symbol;Acc:HGNC:28817]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042645//mitochondrial nucleoid;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007165//signal transduction;GO:0046579//positive regulation of Ras protein signal transduction	--
ENSG00000108830	2.989	2.881	2.886	2.518	2.605	3.168	258	250	184	161	190	199	RND2	Rho family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:18315]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0005769//early endosome;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0047485//protein N-terminus binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0048672//positive regulation of collateral sprouting	--
ENSG00000108839	0	0.08	0	0	0.024	0.028	0	4	0	0	1	1	ALOX12	"arachidonate 12-lipoxygenase, 12S type [Source:HGNC Symbol;Acc:HGNC:429]"	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Human Diseases	Global and overview maps;Nervous system;Sensory system;Lipid metabolism;Drug resistance: antineoplastic	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko04750//Inflammatory mediator regulation of TRP channels;ko00590//Arachidonic acid metabolism;ko01523//Antifolate resistance	K00458;K00458;K00458;K00458;K00458	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042383//sarcolemma;GO:0070062//extracellular exosome	"GO:0004052//arachidonate 12(S)-lipoxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016165//linoleate 13S-lipoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047977//hepoxilin-epoxide hydrolase activity;GO:0050473//arachidonate 15-lipoxygenase activity;GO:0051213//dioxygenase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0019395//fatty acid oxidation;GO:0033559//unsaturated fatty acid metabolic process;GO:0034440//lipid oxidation;GO:0042554//superoxide anion generation;GO:0043651//linoleic acid metabolic process;GO:0051122//hepoxilin biosynthetic process;GO:0061436//establishment of skin barrier;GO:0090331//negative regulation of platelet aggregation;GO:1901751//leukotriene A4 metabolic process;GO:2001303//lipoxin A4 biosynthetic process;GO:2001306//lipoxin B4 biosynthetic process	--
ENSG00000108840	25.752	26.702	28.158	29.403	29.779	28.578	2164	2172.6	1695	1800	1994	1584	HDAC5	histone deacetylase 5 [Source:HGNC Symbol;Acc:HGNC:14068]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Immune system;Cancer: overview;Substance dependence;Cancer: overview;Signal transduction	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism;ko05206//MicroRNAs in cancer;ko04371//Apelin signaling pathway	K11406;K11406;K11406;K11406;K11406	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0004407//histone deacetylase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033558//protein deacetylase activity;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006476//protein deacetylation;GO:0006954//inflammatory response;GO:0010830//regulation of myotube differentiation;GO:0010832//negative regulation of myotube differentiation;GO:0016575//histone deacetylation;GO:0030183//B cell differentiation;GO:0031507//heterochromatin assembly;GO:0032869//cellular response to insulin stimulus;GO:0040029//regulation of gene expression, epigenetic;GO:0042113//B cell activation;GO:0043393//regulation of protein binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis"	--
ENSG00000108846	0.009	0.214	0.075	0.277	0.138	0	1	11	2	6	6	0	ABCC3	ATP binding cassette subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:54]	Organismal Systems;Environmental Information Processing;Human Diseases	Digestive system;Membrane transport;Drug resistance: antineoplastic	ko04976//Bile secretion;ko02010//ABC transporters;ko01523//Antifolate resistance	K05667;K05667;K05667	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015164//glucuronoside transmembrane transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0015432//ABC-type bile acid transporter activity;GO:0022857//transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0071714//icosanoid transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0015698//inorganic anion transport;GO:0015721//bile acid and bile salt transport;GO:0015779//glucuronoside transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0071716//leukotriene transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000108848	16.093	11.616	15.374	7.46	10.756	13.652	811	618	548	308	533	552	LUC7L3	LUC7 like 3 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:24309]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005685//U1 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000108849	0	0	0	0	0	0	0	0	0	0	0	0	PPY	pancreatic polypeptide [Source:HGNC Symbol;Acc:HGNC:9327]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05234	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0031841//neuropeptide Y receptor binding	GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0009306//protein secretion	--
ENSG00000108852	15.53	15.946	16.097	21.922	20.735	21.326	1119	1121	864	1137	1272	1116	MPP2	membrane palmitoylated protein 2 [Source:HGNC Symbol;Acc:HGNC:7220]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099031//anchored component of postsynaptic density membrane	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0044325//transmembrane transporter binding;GO:0098919//structural constituent of postsynaptic density	GO:0051260//protein homooligomerization;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0099562//maintenance of postsynaptic density structure	--
ENSG00000108854	7.03	7.08	6.281	4.934	5.499	6.783	591	548	342	311	360	372	SMURF2	SMAD specific E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16809]	Cellular Processes;Genetic Information Processing;Environmental Information Processing;Environmental Information Processing	"Transport and catabolism;Folding, sorting and degradation;Signal transduction;Signal transduction"	ko04144//Endocytosis;ko04120//Ubiquitin mediated proteolysis;ko04350//TGF-beta signaling pathway;ko04340//Hedgehog signaling pathway	K04678;K04678;K04678;K04678	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0045121//membrane raft	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901165//positive regulation of trophoblast cell migration"	--
ENSG00000108861	21.233	20.977	23.04	23.142	22.907	26.324	1761	1757	1410	1456	1594	1603	DUSP3	dual specificity phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:3069]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K17614	GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0033549//MAP kinase phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity;GO:1990782//protein tyrosine kinase binding	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030336//negative regulation of cell migration;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0045931//positive regulation of mitotic cell cycle;GO:0046329//negative regulation of JNK cascade;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0050922//negative regulation of chemotaxis;GO:0051893//regulation of focal adhesion assembly;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0120183//positive regulation of focal adhesion disassembly;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000108878	0	0	0.05	0	0	0	0	0	1	0	0	0	CACNG1	calcium voltage-gated channel auxiliary subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:1405]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04866;K04866;K04866;K04866;K04866;K04866;K04866	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0042383//sarcolemma;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0045933//positive regulation of muscle contraction;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	--
ENSG00000108883	37.223	37.563	36.921	36.442	38.541	32.514	2531	2521	1906	1853	2185	1620	EFTUD2	elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12852	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030623//U5 snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0042220//response to cocaine;GO:0071466//cellular response to xenobiotic stimulus"	--
ENSG00000108924	3.88	3.365	2.726	2.912	3.743	2.935	290	243	194	181	240	174	HLF	"HLF transcription factor, PAR bZIP family member [Source:HGNC Symbol;Acc:HGNC:4977]"	Organismal Systems	Environmental adaptation	ko04711//Circadian rhythm - fly	K09057	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	TF_bZIP
ENSG00000108932	0.157	0.208	0.124	0.106	0.031	0.09	12	16	7	6	2	5	SLC16A6	solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport	--
ENSG00000108946	146.889	144.314	156.8	149.381	160.795	160.042	7802	7401	6125	5913	6921	6207	PRKAR1A	protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K04739	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005771//multivesicular body;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005930//axoneme;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0031588//nucleotide-activated protein kinase complex;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0044853//plasma membrane raft;GO:0045202//synapse;GO:0097224//sperm connecting piece;GO:0097546//ciliary base;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0030552//cAMP binding;GO:0031625//ubiquitin protein ligase binding;GO:0034236//protein kinase A catalytic subunit binding	GO:0001707//mesoderm formation;GO:0001932//regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006469//negative regulation of protein kinase activity;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0045214//sarcomere organization;GO:0046007//negative regulation of activated T cell proliferation;GO:0060038//cardiac muscle cell proliferation;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000108947	9.22	9.784	9.479	8.136	8.748	8.756	615	656	467	402	493	425	EFNB3	ephrin B3 [Source:HGNC Symbol;Acc:HGNC:3228]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05463	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0001618//virus receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	"GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007628//adult walking behavior;GO:0016198//axon choice point recognition;GO:0030154//cell differentiation;GO:0031295//T cell costimulation;GO:0046718//viral entry into host cell;GO:0048013//ephrin receptor signaling pathway;GO:0050771//negative regulation of axonogenesis;GO:0099557//trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission"	--
ENSG00000108950	3.794	2.872	1.203	4.624	5.32	5.781	166	156	73	179	239	191	FAM20A	FAM20A golgi associated secretory pathway pseudokinase [Source:HGNC Symbol;Acc:HGNC:23015]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0001934//positive regulation of protein phosphorylation;GO:0009617//response to bacterium;GO:0031214//biomineral tissue development;GO:0044691//tooth eruption;GO:0055074//calcium ion homeostasis;GO:0070166//enamel mineralization;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000108953	186.25	193.024	190.802	173.928	171.25	186.008	7809	8130	5758	5337	6057	5661	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon [Source:HGNC Symbol;Acc:HGNC:12851]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	Signal transduction;Cancer: overview;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Nervous system	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko04621//NOD-like receptor signaling pathway;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04722//Neurotrophin signaling pathway	K06630;K06630;K06630;K06630;K06630;K06630;K06630;K06630	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0023026//MHC class II protein complex binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity;GO:0050815//phosphoserine residue binding;GO:0051219//phosphoprotein binding;GO:0097110//scaffold protein binding	GO:0000165//MAPK cascade;GO:0001764//neuron migration;GO:0003064//regulation of heart rate by hormone;GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0021762//substantia nigra development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0034504//protein localization to nucleus;GO:0034605//cellular response to heat;GO:0034613//cellular protein localization;GO:0035308//negative regulation of protein dephosphorylation;GO:0035556//intracellular signal transduction;GO:0046827//positive regulation of protein export from nucleus;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0060306//regulation of membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1902309//negative regulation of peptidyl-serine dephosphorylation;GO:1905913//negative regulation of calcium ion export across plasma membrane	--
ENSG00000108960	8.056	8.038	10.718	11.207	9.008	9.495	403	387	346	318	328	308	MMD	monocyte to macrophage differentiation associated [Source:HGNC Symbol;Acc:HGNC:7153]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006468//protein phosphorylation;GO:0019835//cytolysis;GO:0032880//regulation of protein localization;GO:0045666//positive regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity	--
ENSG00000108961	12.483	14.114	16.52	17.745	15.904	15.424	245.78	277.53	248.49	255.95	260.72	222.97	RANGRF	RAN guanine nucleotide release factor [Source:HGNC Symbol;Acc:HGNC:17679]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding	GO:0002027//regulation of heart rate;GO:0003254//regulation of membrane depolarization;GO:0006606//protein import into nucleus;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0032527//protein exit from endoplasmic reticulum;GO:0042391//regulation of membrane potential;GO:0050790//regulation of catalytic activity;GO:0060047//heart contraction;GO:0090226//regulation of microtubule nucleation by Ran protein signal transduction;GO:0098905//regulation of bundle of His cell action potential;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:1902305//regulation of sodium ion transmembrane transport;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000010//positive regulation of protein localization to cell surface;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000108963	8.863	9.374	9.555	10.754	10.004	10.064	475.38	512.36	382.27	419.21	440.77	393.15	DPH1	diphthamide biosynthesis 1 [Source:HGNC Symbol;Acc:HGNC:3003]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0090560//2-(3-amino-3-carboxypropyl)histidine synthase activity	GO:0008283//cell population proliferation;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine	--
ENSG00000108984	4.7	4.051	4.031	3.161	3.036	3.609	672	549	409	251	456	386	MAP2K6	mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Endocrine and metabolic disease;Cardiovascular disease;Immune system;Development and regeneration;Endocrine system;Signal transduction;Infectious disease: parasitic;Immune system;Sensory system;Cancer: overview;Endocrine system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05132//Salmonella infection;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04620//Toll-like receptor signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway"	K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433;K04433	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019211//phosphatase activator activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001649//osteoblast differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006975//DNA damage induced protein phosphorylation;GO:0007165//signal transduction;GO:0009410//response to xenobiotic stimulus;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0022602//ovulation cycle process;GO:0032308//positive regulation of prostaglandin secretion;GO:0038066//p38MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0051403//stress-activated MAPK cascade;GO:0051726//regulation of cell cycle;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060048//cardiac muscle contraction;GO:0060348//bone development;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0072709//cellular response to sorbitol;GO:0090398//cellular senescence;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000109016	22.453	22.06	22.984	21.776	20.484	21.033	567	533	425	396	436	375	DHRS7B	dehydrogenase/reductase 7B [Source:HGNC Symbol;Acc:HGNC:24547]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000140//acylglycerone-phosphate reductase activity;GO:0003674//molecular_function;GO:0003714//transcription corepressor activity;GO:0016491//oxidoreductase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006954//inflammatory response;GO:0008150//biological_process;GO:0008611//ether lipid biosynthetic process;GO:0010468//regulation of gene expression;GO:0030223//neutrophil differentiation;GO:0032091//negative regulation of protein binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050873//brown fat cell differentiation;GO:0060612//adipose tissue development;GO:0120161//regulation of cold-induced thermogenesis"	--
ENSG00000109046	34.335	32.34	31.612	31.118	35.815	33.56	1388	1303	962	972	1240	994	WSB1	WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0008150//biological_process;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0044314//protein K27-linked ubiquitination;GO:0140454//protein aggregate center assembly	--
ENSG00000109047	0.02	0.039	0.159	0.158	0	0	1	2	6	6	0	0	RCVRN	recoverin [Source:HGNC Symbol;Acc:HGNC:9937]	Organismal Systems	Sensory system	ko04744//Phototransduction	K13764	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0016020//membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005509//calcium ion binding;GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0031284//positive regulation of guanylate cyclase activity;GO:0050896//response to stimulus;GO:0051924//regulation of calcium ion transport	--
ENSG00000109061	0	0	0	0	0	0.011	0	0	0	0	0	1	MYH1	myosin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:7567]	-	-	-	-	GO:0005737//cytoplasm;GO:0005859//muscle myosin complex;GO:0014704//intercalated disc;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0031672//A band;GO:0032982//myosin filament;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction	--
ENSG00000109062	314.002	320.125	322.962	372.526	367.333	376.109	11443	11689	8983	10274	11451	10198	SLC9A3R1	SLC9A3 regulator 1 [Source:HGNC Symbol;Acc:HGNC:11075]	Human Diseases;Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Cellular community - eukaryotes;Endocrine system	"ko05165//Human papillomavirus infection;ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko04928//Parathyroid hormone synthesis, secretion and action"	K13365;K13365;K13365;K13365	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030175//filopodium;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0097225//sperm midpiece;GO:0098797//plasma membrane protein complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0015185//gamma-aminobutyric acid transmembrane transporter activity;GO:0017081//chloride channel regulator activity;GO:0019902//phosphatase binding;GO:0019904//protein domain specific binding;GO:0030165//PDZ domain binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0031799//type 2 metabotropic glutamate receptor binding;GO:0031800//type 3 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0043495//protein-membrane adaptor activity;GO:0043621//protein self-association;GO:0044877//protein-containing complex binding;GO:0045159//myosin II binding;GO:0047485//protein N-terminus binding;GO:0050780//dopamine receptor binding;GO:0060090//molecular adaptor activity;GO:0070851//growth factor receptor binding	GO:0002009//morphogenesis of an epithelium;GO:0003096//renal sodium ion transport;GO:0007009//plasma membrane organization;GO:0007097//nuclear migration;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0008361//regulation of cell size;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0010766//negative regulation of sodium ion transport;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016055//Wnt signaling pathway;GO:0022612//gland morphogenesis;GO:0030033//microvillus assembly;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0030643//cellular phosphate ion homeostasis;GO:0032415//regulation of sodium:proton antiporter activity;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0032782//bile acid secretion;GO:0034613//cellular protein localization;GO:0034635//glutathione transport;GO:0034767//positive regulation of ion transmembrane transport;GO:0044782//cilium organization;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0045859//regulation of protein kinase activity;GO:0045930//negative regulation of mitotic cell cycle;GO:0051683//establishment of Golgi localization;GO:0051898//negative regulation of protein kinase B signaling;GO:0051939//gamma-aminobutyric acid import;GO:0060088//auditory receptor cell stereocilium organization;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0065003//protein-containing complex assembly;GO:0070293//renal absorption;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0072659//protein localization to plasma membrane;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090660//cerebrospinal fluid circulation;GO:0097291//renal phosphate ion absorption;GO:0098739//import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903402//regulation of renal phosphate excretion;GO:2000146//negative regulation of cell motility;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000109063	0.04	0.111	0.087	0.043	0.085	0.077	5	14	8	4	9	7	MYH3	myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0032982//myosin filament;GO:0043292//contractile fiber;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017018//myosin phosphatase activity;GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0006470//protein dephosphorylation;GO:0007517//muscle organ development;GO:0030048//actin filament-based movement;GO:0030049//muscle filament sliding;GO:0030326//embryonic limb morphogenesis;GO:0045214//sarcomere organization;GO:0046034//ATP metabolic process;GO:0060325//face morphogenesis	--
ENSG00000109065	9.867	10.852	16.947	11.178	13.678	14.957	313	349	322	249	349	312	NAT9	N-acetyltransferase 9 (putative) [Source:HGNC Symbol;Acc:HGNC:23133]	-	-	-	-	GO:0032991//protein-containing complex	"GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups"	GO:0006473//protein acetylation	--
ENSG00000109066	13.009	13.7	13.228	13.899	15.984	13.652	1269	1249	943	972	1296	969	TMEM104	transmembrane protein 104 [Source:HGNC Symbol;Acc:HGNC:25984]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000109072	2.728	2.419	1.766	12.329	11.16	9.413	92	82	44	308	318	231	VTN	vitronectin [Source:HGNC Symbol;Acc:HGNC:12724]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Immune system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04610//Complement and coagulation cascades;ko04512//ECM-receptor interaction	K06251;K06251;K06251;K06251;K06251;K06251	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0072562//blood microparticle;GO:0098637//protein complex involved in cell-matrix adhesion;GO:1904090//peptidase inhibitor complex	GO:0005044//scavenger receptor activity;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030247//polysaccharide binding;GO:0050840//extracellular matrix binding	GO:0006897//endocytosis;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010951//negative regulation of endopeptidase activity;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016477//cell migration;GO:0030155//regulation of cell adhesion;GO:0030195//negative regulation of blood coagulation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032092//positive regulation of protein binding;GO:0033627//cell adhesion mediated by integrin;GO:0035987//endodermal cell differentiation;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051918//negative regulation of fibrinolysis;GO:0061302//smooth muscle cell-matrix adhesion;GO:0090303//positive regulation of wound healing	--
ENSG00000109079	19.903	20.547	21.242	20.502	20.936	19.371	1469.83	1524.51	1135.4	1124.54	1309.76	1043.68	TNFAIP1	TNF alpha induced protein 1 [Source:HGNC Symbol;Acc:HGNC:11894]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043149//stress fiber assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045740//positive regulation of DNA replication;GO:0051260//protein homooligomerization	--
ENSG00000109083	8.648	9.97	11.329	8.684	7.374	9.255	168.54	195.38	159.58	124.98	120	129.04	IFT20	intraflagellar transport 20 [Source:HGNC Symbol;Acc:HGNC:30989]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0032420//stereocilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0044292//dendrite terminus;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:1902636//kinociliary basal body	GO:0002046//opsin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0001736//establishment of planar polarity;GO:0001822//kidney development;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0008542//visual learning;GO:0022008//neurogenesis;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0034067//protein localization to Golgi apparatus;GO:0035720//intraciliary anterograde transport;GO:0035845//photoreceptor cell outer segment organization;GO:0036372//opsin transport;GO:0042073//intraciliary transport;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0051642//centrosome localization;GO:0055007//cardiac muscle cell differentiation;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060271//cilium assembly;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061351//neural precursor cell proliferation;GO:0061512//protein localization to cilium;GO:0072659//protein localization to plasma membrane;GO:0090102//cochlea development;GO:1902017//regulation of cilium assembly;GO:2000583//regulation of platelet-derived growth factor receptor-alpha signaling pathway;GO:2000785//regulation of autophagosome assembly	--
ENSG00000109084	10.743	10.995	9.049	10.069	9.895	7.668	537.46	550.62	341.42	381.02	424	266.96	TMEM97	transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106]	-	-	-	-	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0001558//regulation of cell growth;GO:0042632//cholesterol homeostasis	--
ENSG00000109089	5.017	4.788	4.8	4.436	4.035	4.347	368	353	260	241	250	232	CDR2L	cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000109099	40.9	41.182	43.442	31.858	30.589	34.839	1589	1594	1241	912	1015	986	PMP22	peripheral myelin protein 22 [Source:HGNC Symbol;Acc:HGNC:9118]	-	-	-	-	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043218//compact myelin;GO:0045202//synapse	GO:0005515//protein binding	GO:0007268//chemical synaptic transmission;GO:0007422//peripheral nervous system development;GO:0008219//cell death;GO:0008285//negative regulation of cell population proliferation;GO:0010977//negative regulation of neuron projection development;GO:0030154//cell differentiation;GO:0032060//bleb assembly;GO:0032288//myelin assembly;GO:0042552//myelination	--
ENSG00000109101	0.028	0	0	0	0	0.077	2	0	0	0	0	4	FOXN1	forkhead box N1 [Source:HGNC Symbol;Acc:HGNC:12765]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001942//hair follicle development;GO:0002260//lymphocyte homeostasis;GO:0002360//T cell lineage commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0008544//epidermis development;GO:0009887//animal organ morphogenesis;GO:0010468//regulation of gene expression;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0033081//regulation of T cell differentiation in thymus;GO:0035878//nail development;GO:0043029//T cell homeostasis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0048538//thymus development;GO:0051798//positive regulation of hair follicle development;GO:0097535//lymphoid lineage cell migration into thymus;GO:0097536//thymus epithelium morphogenesis;GO:1902232//regulation of positive thymic T cell selection"	Fork_head
ENSG00000109103	35.281	35.892	46.216	59.535	55.039	63.028	1109	1130	1103	1395	1459	1442	UNC119	unc-119 lipid binding chaperone [Source:HGNC Symbol;Acc:HGNC:12565]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0045171//intercellular bridge;GO:0045202//synapse;GO:0051233//spindle midzone	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0000281//mitotic cytokinesis;GO:0006897//endocytosis;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0015031//protein transport;GO:0042953//lipoprotein transport;GO:0050896//response to stimulus;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:1900186//negative regulation of clathrin-dependent endocytosis;GO:2001287//negative regulation of caveolin-mediated endocytosis	--
ENSG00000109107	18.202	18.184	22.036	25.603	25.342	25.643	602	608	541	634	715	622	ALDOC	"aldolase, fructose-bisphosphate C [Source:HGNC Symbol;Acc:HGNC:418]"	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K01623;K01623;K01623;K01623;K01623;K01623;K01623	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003824//catalytic activity;GO:0004332//fructose-bisphosphate aldolase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0016829//lyase activity	"GO:0006000//fructose metabolic process;GO:0006096//glycolytic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0030855//epithelial cell differentiation"	--
ENSG00000109111	45.256	45.667	47.451	46.958	45.914	45.741	5628	5657	4373	4215	4800	3952	SUPT6H	"SPT6 homolog, histone chaperone and transcription elongation factor [Source:HGNC Symbol;Acc:HGNC:11470]"	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding	GO:0001825//blastocyst formation;GO:0006139//nucleobase-containing compound metabolic process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010793//regulation of mRNA export from nucleus;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045191//regulation of isotype switching;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:0051147//regulation of muscle cell differentiation;GO:0061086//negative regulation of histone H3-K27 methylation	--
ENSG00000109113	41.724	46.89	51.084	52.244	46.668	47.978	1286	1388	1052	1210	1224	1026	RAB34	"RAB34, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16519]"	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005929//cilium;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0031985//Golgi cisterna;GO:0042995//cell projection;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0019882//antigen processing and presentation;GO:0030030//cell projection organization;GO:0032418//lysosome localization;GO:0043001//Golgi to plasma membrane protein transport;GO:0045880//positive regulation of smoothened signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0090382//phagosome maturation;GO:0090385//phagosome-lysosome fusion	--
ENSG00000109118	11.884	10.197	9.828	10.048	13.439	13.965	992	970	698	703	903	759	PHF12	PHD finger protein 12 [Source:HGNC Symbol;Acc:HGNC:20816]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0017053//transcription repressor complex;GO:0070822//Sin3-type complex	GO:0001222//transcription corepressor binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000109132	0	0	0	0	0	0	0	0	0	0	0	0	PHOX2B	paired like homeobox 2B [Source:HGNC Symbol;Acc:HGNC:9143]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001764//neuron migration;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0003357//noradrenergic neuron differentiation;GO:0003358//noradrenergic neuron development;GO:0003360//brainstem development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0010001//glial cell differentiation;GO:0010468//regulation of gene expression;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0021533//cell differentiation in hindbrain;GO:0021723//medullary reticular formation development;GO:0021934//hindbrain tangential cell migration;GO:0030182//neuron differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0048483//autonomic nervous system development;GO:0048484//enteric nervous system development;GO:0048485//sympathetic nervous system development;GO:0048486//parasympathetic nervous system development;GO:0048839//inner ear development;GO:0048894//efferent axon development in a lateral line nerve;GO:0060541//respiratory system development;GO:0061452//retrotrapezoid nucleus neuron differentiation;GO:0061549//sympathetic ganglion development;GO:0071542//dopaminergic neuron differentiation;GO:0071773//cellular response to BMP stimulus;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901166//neural crest cell migration involved in autonomic nervous system development"	Homeobox
ENSG00000109133	32.396	29.032	26.228	28.208	26.237	34.984	1755	1471	1120.11	1093	1182	1400	TMEM33	transmembrane protein 33 [Source:HGNC Symbol;Acc:HGNC:25541]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K20724	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042470//melanosome	GO:0005515//protein binding	GO:0034976//response to endoplasmic reticulum stress;GO:0061024//membrane organization;GO:0071786//endoplasmic reticulum tubular network organization;GO:1903371//regulation of endoplasmic reticulum tubular network organization;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:1903899//positive regulation of PERK-mediated unfolded protein response	--
ENSG00000109158	0	0	0	0	0	0	0	0	0	0	0	0	GABRA4	gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000109163	0.033	0.022	0.015	0.03	0	0.015	3	2	1	2	0	1	GNRHR	gonadotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4421]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04912//GnRH signaling pathway	K04280;K04280	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004968//gonadotropin-releasing hormone receptor activity;GO:0016500//protein-hormone receptor activity;GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007275//multicellular organism development;GO:0097211//cellular response to gonadotropin-releasing hormone	--
ENSG00000109171	7.38	6.633	7.243	6.533	6.384	7.022	844	752	579	489	645	596	SLAIN2	SLAIN motif family member 2 [Source:HGNC Symbol;Acc:HGNC:29282]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end	GO:0005515//protein binding	GO:0007020//microtubule nucleation;GO:0031113//regulation of microtubule polymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization	--
ENSG00000109180	110.808	107.855	109.636	99.83	111.643	124.097	2350	2265	1684	1583	1980	1880	OCIAD1	OCIA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16074]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0005515//protein binding	GO:0006897//endocytosis;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0061484//hematopoietic stem cell homeostasis;GO:2000736//regulation of stem cell differentiation	--
ENSG00000109181	0	0	0	0	0	0	0	0	0	0	0	0	UGT2B10	UDP glucuronosyltransferase family 2 member B10 [Source:HGNC Symbol;Acc:HGNC:12544]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process	--
ENSG00000109182	0	0	0	0	0	0	0	0	0	0	0	0	CWH43	cell wall biogenesis 43 C-terminal homolog [Source:HGNC Symbol;Acc:HGNC:26133]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000109184	8.133	7.742	8.086	7.299	6.542	8.194	687	531	449	388	430	464	DCUN1D4	defective in cullin neddylation 1 domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28998]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding	GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:2000436//positive regulation of protein neddylation	--
ENSG00000109189	14.577	11.862	11.91	10.914	11.547	12.418	1292	1130	838	768	871	794	USP46	ubiquitin specific peptidase 46 [Source:HGNC Symbol;Acc:HGNC:20075]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0101005//deubiquitinase activity	"GO:0001662//behavioral fear response;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007610//behavior;GO:0008343//adult feeding behavior;GO:0016579//protein deubiquitination;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048149//behavioral response to ethanol;GO:0060013//righting reflex"	--
ENSG00000109193	0.163	0.433	0.037	0.073	0.064	0.26	6	16	1	2	2	6.95	SULT1E1	sulfotransferase family 1E member 1 [Source:HGNC Symbol;Acc:HGNC:11377]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K01016;K01016	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0004062//aryl sulfotransferase activity;GO:0004304//estrone sulfotransferase activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0008289//lipid binding;GO:0016740//transferase activity;GO:0047894//flavonol 3-sulfotransferase activity;GO:0050294//steroid sulfotransferase activity	GO:0006068//ethanol catabolic process;GO:0006629//lipid metabolic process;GO:0006711//estrogen catabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0045600//positive regulation of fat cell differentiation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000109205	0.736	0.564	0.359	0.662	0.146	0.968	14	10	6	8	2	13	ODAM	"odontogenic, ameloblast associated [Source:HGNC Symbol;Acc:HGNC:26043]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0072686//mitotic spindle;GO:0099512//supramolecular fiber	GO:0005515//protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006954//inflammatory response;GO:0009611//response to wounding;GO:0010628//positive regulation of gene expression;GO:0031214//biomineral tissue development;GO:0032956//regulation of actin cytoskeleton organization;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043547//positive regulation of GTPase activity;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing	--
ENSG00000109208	0	0	0	0	0	0	0	0	0	0	0	0	SMR3A	submaxillary gland androgen regulated protein 3A [Source:HGNC Symbol;Acc:HGNC:19216]	-	-	-	-	GO:0005576//extracellular region	GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding	GO:0010951//negative regulation of endopeptidase activity;GO:0051930//regulation of sensory perception of pain	--
ENSG00000109220	12.382	12.413	13.484	9.155	10.446	13.742	272	287	222	156	203	230	CHIC2	cysteine rich hydrophobic domain 2 [Source:HGNC Symbol;Acc:HGNC:1935]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000109255	0.118	0.176	0.24	0.912	1.128	0.812	2	3	3	11	16	10	NMU	neuromedin U [Source:HGNC Symbol;Acc:HGNC:7859]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05249	GO:0005576//extracellular region;GO:0043195//terminal bouton	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031839//type 1 neuromedin U receptor binding;GO:0031840//type 2 neuromedin U receptor binding;GO:0042922//neuromedin U receptor binding	GO:0001659//temperature homeostasis;GO:0006940//regulation of smooth muscle contraction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0045987//positive regulation of smooth muscle contraction;GO:0050806//positive regulation of synaptic transmission;GO:0060259//regulation of feeding behavior;GO:0097009//energy homeostasis;GO:2000821//regulation of grooming behavior	--
ENSG00000109265	6.156	5.923	4.671	3.474	4.839	5.008	849	818	504	376	554	472	CRACD	capping protein inhibiting regulator of actin dynamics [Source:HGNC Symbol;Acc:HGNC:29219]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0010669//epithelial structure maintenance;GO:0030277//maintenance of gastrointestinal epithelium;GO:0030838//positive regulation of actin filament polymerization;GO:2000813//negative regulation of barbed-end actin filament capping	--
ENSG00000109270	33.275	31.011	33.413	32.577	29.644	39.501	1390	1258	993	951	1002	1102	LAMTOR3	"late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606]"	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04150//mTOR signaling pathway	K04370;K04370	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0071986//Ragulator complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019209//kinase activator activity;GO:0060090//molecular adaptor activity	GO:0032006//regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0033674//positive regulation of kinase activity;GO:0034613//cellular protein localization;GO:0038202//TORC1 signaling;GO:0043410//positive regulation of MAPK cascade;GO:0050790//regulation of catalytic activity;GO:0071230//cellular response to amino acid stimulus;GO:1902414//protein localization to cell junction	--
ENSG00000109272	0.065	0	0	0	0	0	1	0	0	0	0	0	PF4V1	platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05407;K05407;K05407	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0045236//CXCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000109320	8.577	8.763	8.518	7.28	7.858	8.687	628	706	497	430	527	455	NFKB1	nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Cancer: specific types;Immune system;Cancer: overview;Immune system;Aging;Cancer: specific types;Cancer: specific types;Infectious disease: bacterial;Cancer: specific types;Endocrine system;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune disease;Immune system;Infectious disease: bacterial;Substance dependence;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04066//HIF-1 signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04211//Longevity regulating pathway;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05133//Pertussis;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05221//Acute myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko05321//Inflammatory bowel disease;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis;ko05030//Cocaine addiction;ko01523//Antifolate resistance	K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580;K02580	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0033256//I-kappaB/NF-kappaB complex;GO:0034774//secretory granule lumen;GO:0035580//specific granule lumen	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042805//actinin binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001818//negative regulation of cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010884//positive regulation of lipid storage;GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032375//negative regulation of cholesterol transport;GO:0032479//regulation of type I interferon production;GO:0032695//negative regulation of interleukin-12 production;GO:0035994//response to muscle stretch;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050728//negative regulation of inflammatory response;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0071316//cellular response to nicotine;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0071359//cellular response to dsRNA;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098586//cellular response to virus;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:1904385//cellular response to angiotensin;GO:2000630//positive regulation of miRNA metabolic process"	RHD
ENSG00000109321	0.469	0.194	0.793	0.264	0.092	0.297	12	5	15	5	2	5	AREG	amphiregulin [Source:HGNC Symbol;Acc:HGNC:651]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Cancer: specific types;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04390//Hippo signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway	K09782;K09782;K09782;K09782;K09782	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005125//cytokine activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0014009//glial cell proliferation;GO:0014070//response to organic cyclic compound;GO:0031175//neuron projection development;GO:0032355//response to estradiol;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0042542//response to hydrogen peroxide;GO:0043434//response to peptide hormone;GO:0045668//negative regulation of osteoblast differentiation;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0051897//positive regulation of protein kinase B signaling;GO:0060598//dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis;GO:0060744//mammary gland branching involved in thelarche;GO:0060749//mammary gland alveolus development;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation	--
ENSG00000109323	31.442	32.102	28.296	26.378	26.699	28.309	2086	2160	1388	1334	1543	1400	MANBA	mannosidase beta [Source:HGNC Symbol;Acc:HGNC:6831]	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K01192;K01192	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane;GO:0043202//lysosomal lumen	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004567//beta-mannosidase activity;GO:0005537//mannose binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0006516//glycoprotein catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process	--
ENSG00000109332	122.616	112.865	107.974	126.925	112.79	130.276	4415	4282	3053	3216	3470	3367	UBE2D3	ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation;Folding, sorting and degradation"	ko05131//Shigellosis;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K06689;K06689;K06689	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061630//ubiquitin protein ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006513//protein monoubiquitination;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0030514//negative regulation of BMP signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000109339	5.267	6.282	5.286	4.284	3.854	4.336	277.36	267.01	188	164	174	158	MAPK10	mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:HGNC:6872]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	"Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Immune system;Cellular community - eukaryotes;Signal transduction;Folding, sorting and degradation;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Transport and catabolism;Nervous system;Infectious disease: viral;Neurodegenerative disease;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Endocrine system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Immune system;Endocrine system;Cancer: specific types;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Endocrine system;Transport and catabolism;Immune system;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Cell growth and death"	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04530//Tight junction;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko05212//Pancreatic cancer;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus;ko04215//Apoptosis - multiple species"	K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440;K04440	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004705//JUN kinase activity;GO:0004707//MAP kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0009416//response to light stimulus;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0090398//cellular senescence	--
ENSG00000109381	8.975	8.313	6.525	6.185	6.824	6.936	462	425	258	228	291	262	ELF2	E74 like ETS transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3317]	Cellular Processes	Cell growth and death	ko04214//Apoptosis - fly	K09428	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051171//regulation of nitrogen compound metabolic process;GO:0060255//regulation of macromolecule metabolic process;GO:0080090//regulation of primary metabolic process"	ETS
ENSG00000109390	22.51	20.671	21.639	28.743	21.232	25.859	386.29	340.44	266.07	338.94	302	297.52	NDUFC1	NADH:ubiquinone oxidoreductase subunit C1 [Source:HGNC Symbol;Acc:HGNC:7705]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967;K03967	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000109424	0.119	0.503	0.081	0.12	0	0	4	17	2	3	0	0	UCP1	uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517]	Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Neurodegenerative disease;Environmental adaptation;Signal transduction;Endocrine system	ko05016//Huntington disease;ko04714//Thermogenesis;ko04371//Apelin signaling pathway;ko03320//PPAR signaling pathway	K08769;K08769;K08769;K08769	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005525//GTP binding;GO:0017077//oxidative phosphorylation uncoupler activity;GO:0019003//GDP binding;GO:0022857//transmembrane transporter activity;GO:0032555//purine ribonucleotide binding;GO:0036041//long-chain fatty acid binding;GO:1901612//cardiolipin binding	GO:0002024//diet induced thermogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006811//ion transport;GO:0006839//mitochondrial transport;GO:0009266//response to temperature stimulus;GO:0009409//response to cold;GO:0031667//response to nutrient levels;GO:0032870//cellular response to hormone stimulus;GO:0034614//cellular response to reactive oxygen species;GO:0050873//brown fat cell differentiation;GO:0070417//cellular response to cold;GO:0071398//cellular response to fatty acid;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902600//proton transmembrane transport;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1903495//cellular response to dehydroepiandrosterone;GO:1990542//mitochondrial transmembrane transport;GO:1990845//adaptive thermogenesis	--
ENSG00000109436	20.33	18.153	17.712	15.961	15.905	16.13	2342	2102	1507	1362	1548	1352	TBC1D9	TBC1 domain family member 9 [Source:HGNC Symbol;Acc:HGNC:21710]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0090630//activation of GTPase activity	--
ENSG00000109445	37.866	37.91	39.225	41.111	41.393	52.416	1418	1391	1086	1175	1297	1426	ZNF330	zinc finger protein 330 [Source:HGNC Symbol;Acc:HGNC:15462]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030496//midbody"	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008150//biological_process	--
ENSG00000109452	3.442	2.809	2.692	2.065	2.45	1.966	493	333	204	194	266	199	INPP4B	inositol polyphosphate-4-phosphatase type II B [Source:HGNC Symbol;Acc:HGNC:6075]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01109;K01109;K01109	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity;GO:0016787//hydrolase activity;GO:0017161//inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;GO:0052828//inositol-3,4-bisphosphate 4-phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0016311//dephosphorylation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000109458	30.811	28.093	25.732	20.699	24.959	27.242	2871	2578	1843	1368	1824	1835	GAB1	GRB2 associated binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4066]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Nervous system;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types	ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko05225//Hepatocellular carcinoma;ko05226//Gastric cancer;ko04722//Neurotrophin signaling pathway;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05211//Renal cell carcinoma	K09593;K09593;K09593;K09593;K09593;K09593;K09593;K09593;K09593;K09593	GO:0005829//cytosol;GO:0005911//cell-cell junction	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0035728//response to hepatocyte growth factor;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0090668//endothelial cell chemotaxis to vascular endothelial growth factor	--
ENSG00000109466	12.367	10.914	11.361	12.954	12.95	15.716	706	619	476	571	631	665	KLHL2	kelch like family member 2 [Source:HGNC Symbol;Acc:HGNC:6353]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0016567//protein ubiquitination	--
ENSG00000109471	0	0	0	0	0	0	0	0	0	0	0	0	IL2	interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Immune disease;Immune system;Immune system;Immune system;Immune disease;Infectious disease: parasitic;Immune system;Signaling molecules and interaction;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko05135//Yersinia infection;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429;K05429	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0019209//kinase activator activity;GO:0030246//carbohydrate binding;GO:0031851//kappa-type opioid receptor binding;GO:0043208//glycosphingolipid binding	GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002366//leukocyte activation involved in immune response;GO:0002376//immune system process;GO:0002639//positive regulation of immunoglobulin production;GO:0002903//negative regulation of B cell apoptotic process;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0010467//gene expression;GO:0030101//natural killer cell activation;GO:0030217//T cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030890//positive regulation of B cell proliferation;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0033674//positive regulation of kinase activity;GO:0034105//positive regulation of tissue remodeling;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0045471//response to ethanol;GO:0045582//positive regulation of T cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045822//negative regulation of heart contraction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046013//regulation of T cell homeostatic proliferation;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050672//negative regulation of lymphocyte proliferation;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0060999//positive regulation of dendritic spine development;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1900100//positive regulation of plasma cell differentiation;GO:2000320//negative regulation of T-helper 17 cell differentiation	--
ENSG00000109472	37.4	39.865	38.327	39.097	42.191	43.344	2003	2146	1516	1551	1909	1689	CPE	carboxypeptidase E [Source:HGNC Symbol;Acc:HGNC:2303]	Human Diseases	Endocrine and metabolic disease	ko04940//Type I diabetes mellitus	K01294	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042043//neurexin family protein binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0003214//cardiac left ventricle morphogenesis;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0007218//neuropeptide signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016485//protein processing;GO:0030070//insulin processing;GO:0030072//peptide hormone secretion;GO:0033366//protein localization to secretory granule;GO:0072657//protein localization to membrane	--
ENSG00000109475	163.185	161.463	158.381	171.209	143.056	144.517	1899	1883	1356	1478	1399	1230	RPL34	ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02915;K02915	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000109501	39.71	39.545	42.845	40.028	40.618	43.192	2906	2941	2316	2173	2529	2306	WFS1	wolframin ER transmembrane glycoprotein [Source:HGNC Symbol;Acc:HGNC:12762]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14020	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0031625//ubiquitin protein ligase binding;GO:0048306//calcium-dependent protein binding;GO:0051117//ATPase binding;GO:0070628//proteasome binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0003091//renal water homeostasis;GO:0006983//ER overload response;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0022417//protein maturation by protein folding;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031016//pancreas development;GO:0031398//positive regulation of protein ubiquitination;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0042048//olfactory behavior;GO:0042593//glucose homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0045927//positive regulation of growth;GO:0050821//protein stabilization;GO:0050877//nervous system process;GO:0051247//positive regulation of protein metabolic process;GO:0051928//positive regulation of calcium ion transport;GO:0055074//calcium ion homeostasis;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903573//negative regulation of response to endoplasmic reticulum stress;GO:1903892//negative regulation of ATF6-mediated unfolded protein response;GO:2000675//negative regulation of type B pancreatic cell apoptotic process	--
ENSG00000109511	0	0	0	0	0	0	0	0	0	0	0	0	ANXA10	annexin A10 [Source:HGNC Symbol;Acc:HGNC:534]	-	-	-	-	GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding	-	--
ENSG00000109519	8.923	9.202	10.137	9.813	10.282	9.591	491	509	412	400	478	384	GRPEL1	"GrpE like 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:19696]"	-	-	-	-	"GO:0001405//PAM complex, Tim23 associated import motor;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005759//mitochondrial matrix"	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0006886//intracellular protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000109534	4.56	5.124	5.359	5.279	4.623	7.312	96	108	83	82	82	112	GAR1	GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11128	"GO:0000781//chromosome, telomeric region;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0031429//box H/ACA snoRNP complex;GO:0072589//box H/ACA scaRNP complex;GO:0090661//box H/ACA telomerase RNP complex"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding	GO:0000454//snoRNA guided rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing;GO:0007004//telomere maintenance via telomerase;GO:0042254//ribosome biogenesis	--
ENSG00000109536	9.588	11.88	9.432	8.411	8.91	8.177	187	235	131	122	151	116	FRG1	FSHD region gene 1 [Source:HGNC Symbol;Acc:HGNC:3954]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0030018//Z disc;GO:0055120//striated muscle dense body;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0007517//muscle organ development;GO:0008380//RNA splicing;GO:0042254//ribosome biogenesis"	--
ENSG00000109572	61.837	57.141	56.887	57.91	52.726	55.041	5954	5539	4005	3425	4280	3914	CLCN3	chloride voltage-gated channel 3 [Source:HGNC Symbol;Acc:HGNC:2021]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K05012	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0030285//integral component of synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032587//ruffle membrane;GO:0042581//specific granule;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0055037//recycling endosome;GO:0060077//inhibitory synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0030165//PDZ domain binding;GO:0072320//volume-sensitive chloride channel activity	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006885//regulation of pH;GO:0006911//phagocytosis, engulfment;GO:0008344//adult locomotory behavior;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0045494//photoreceptor cell maintenance;GO:0045794//negative regulation of cell volume;GO:0048388//endosomal lumen acidification;GO:0051932//synaptic transmission, GABAergic;GO:0055085//transmembrane transport;GO:0070050//neuron cellular homeostasis;GO:0097401//synaptic vesicle lumen acidification;GO:1902476//chloride transmembrane transport;GO:1903428//positive regulation of reactive oxygen species biosynthetic process"	--
ENSG00000109576	6.994	7.465	8.855	6.19	7.374	8.894	309	346	283	214	275	302	AADAT	aminoadipate aminotransferase [Source:HGNC Symbol;Acc:HGNC:17929]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Global and overview maps	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00380//Tryptophan metabolism;ko01210//2-Oxocarboxylic acid metabolism	K00825;K00825;K00825;K00825	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0047536//2-aminoadipate transaminase activity	GO:0006103//2-oxoglutarate metabolic process;GO:0006536//glutamate metabolic process;GO:0009058//biosynthetic process;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0070189//kynurenine metabolic process;GO:0097052//L-kynurenine metabolic process;GO:1901605//alpha-amino acid metabolic process	--
ENSG00000109586	14.15	12.226	9.525	13.093	11.695	13.385	950	798	515	630	716	624	GALNT7	polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0034645//cellular macromolecule biosynthetic process	--
ENSG00000109606	41.506	37.373	37.93	31.827	34.224	41.109	2581	2336	1742	1466	1798	1860	DHX15	DEAH-box helicase 15 [Source:HGNC Symbol;Acc:HGNC:2738]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12820	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0071008//U2-type post-mRNA release spliceosomal complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0009636//response to toxic substance;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043279//response to alkaloid;GO:0051607//defense response to virus;GO:0140374//antiviral innate immune response	--
ENSG00000109610	29.213	29.063	35.635	36.404	34.497	35.47	858	858	773	792	856	758	SOD3	superoxide dismutase 3 [Source:HGNC Symbol;Acc:HGNC:11181]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004784//superoxide dismutase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0006801//superoxide metabolic process;GO:0006979//response to oxidative stress;GO:0019430//removal of superoxide radicals;GO:0046688//response to copper ion;GO:0097746//blood vessel diameter maintenance	--
ENSG00000109618	2.187	2.249	1.931	2.348	1.513	1.974	230	197	157	134	145	139	SEPSECS	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase [Source:HGNC Symbol;Acc:HGNC:30605]	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00450//Selenocompound metabolism	K03341;K03341;K03341	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016785//selenotransferase activity;GO:0098621//phosphoseryl-selenocysteinyl-tRNA selenium transferase activity	GO:0001514//selenocysteine incorporation;GO:0006412//translation;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process	--
ENSG00000109625	44.679	53.28	47.444	79.345	68.992	55.523	2010.77	2414.08	1577	2649.65	2628.68	1827.3	CPZ	carboxypeptidase Z [Source:HGNC Symbol;Acc:HGNC:2333]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0016055//Wnt signaling pathway;GO:0016485//protein processing	--
ENSG00000109654	9.121	6.49	6.519	4.504	6.042	5.832	1241	901.78	662	479	662	622	TRIM2	tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974]	-	-	-	-	GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043523//regulation of neuron apoptotic process	--
ENSG00000109667	0.698	0.592	0.805	0.803	0.765	1.209	27	23	23	23	25	34	SLC2A9	solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0005351//carbohydrate:proton symporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0015143//urate transmembrane transporter activity;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0008645//hexose transmembrane transport;GO:0015747//urate transport;GO:0015749//monosaccharide transmembrane transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000109670	2.529	2.103	1.613	2.099	1.645	1.412	193	146	112	101	115	98	FBXW7	F-box and WD repeat domain containing 7 [Source:HGNC Symbol;Acc:HGNC:16712]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10260	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:1990452//Parkin-FBXW7-Cul1 ubiquitin ligase complex	GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0050816//phosphothreonine residue binding;GO:0097027//ubiquitin-protein transferase activator activity	GO:0001570//vasculogenesis;GO:0001944//vasculature development;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007062//sister chromatid cohesion;GO:0007219//Notch signaling pathway;GO:0010629//negative regulation of gene expression;GO:0010868//negative regulation of triglyceride biosynthetic process;GO:0010883//regulation of lipid storage;GO:0010992//ubiquitin recycling;GO:0016567//protein ubiquitination;GO:0030324//lung development;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031648//protein destabilization;GO:0032880//regulation of protein localization;GO:0034644//cellular response to UV;GO:0042752//regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045746//negative regulation of Notch signaling pathway;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0055088//lipid homeostasis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1903146//regulation of autophagy of mitochondrion;GO:1903378//positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000346//negative regulation of hepatocyte proliferation;GO:2000639//negative regulation of SREBP signaling pathway;GO:2001205//negative regulation of osteoclast development	--
ENSG00000109674	0.102	0.142	0.083	0.22	0.048	0.308	5	7	3	8	2	11	NEIL3	nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10569	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	"GO:0000405//bubble DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016829//lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0046872//metal ion binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:1904931//MCM complex binding"	"GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006285//base-excision repair, AP site formation;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0036297//interstrand cross-link repair;GO:0045007//depurination"	--
ENSG00000109680	9.938	8.825	7.949	6.824	8.598	9.029	386	400	230	198	263	238	TBC1D19	TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000109684	0	0	0	0	0	0	0	0	0	0	0	0	CLNK	cytokine dependent hematopoietic cell linker [Source:HGNC Symbol;Acc:HGNC:17438]	-	-	-	-	GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0042629//mast cell granule	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0002729//positive regulation of natural killer cell cytokine production;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010941//regulation of cell death;GO:0032815//negative regulation of natural killer cell activation;GO:0035556//intracellular signal transduction;GO:0043303//mast cell degranulation	--
ENSG00000109685	20.012	18.749	20.384	14.196	16.373	16.919	2107	2083	1557	1188	1453	1363	NSD2	nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05202//Transcriptional misregulation in cancer;ko00310//Lysine degradation	K11424;K11424;K11424	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031981//nuclear lumen	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003149//membranous septum morphogenesis;GO:0003289//atrial septum primum morphogenesis;GO:0003290//atrial septum secundum morphogenesis;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006807//nitrogen compound metabolic process;GO:0010452//histone H3-K36 methylation;GO:0032259//methylation;GO:0034770//histone H4-K20 methylation;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0048298//positive regulation of isotype switching to IgA isotypes;GO:0060348//bone development;GO:0070201//regulation of establishment of protein localization;GO:2001032//regulation of double-strand break repair via nonhomologous end joining"	HMG
ENSG00000109686	12.993	11.456	10.841	8.051	10.823	9.919	1366	1194	827	621	892	756	SH3D19	SH3 domain containing 19 [Source:HGNC Symbol;Acc:HGNC:30418]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0070064//proline-rich region binding	GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis	--
ENSG00000109689	42.536	35.265	29.528	20.336	26.683	26.444	3196	2706	1767	1193	1674	1553	STIM2	stromal interaction molecule 2 [Source:HGNC Symbol;Acc:HGNC:19205]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K18196	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043229//intracellular organelle	GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0046872//metal ion binding	GO:0002115//store-operated calcium entry;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0032237//activation of store-operated calcium channel activity;GO:0051928//positive regulation of calcium ion transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000109705	0.064	0	0	0	0	0	3	0	0	0	0	0	NKX3-2	NK3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:951]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0030154//cell differentiation;GO:0031016//pancreas development;GO:0032331//negative regulation of chondrocyte differentiation;GO:0042474//middle ear morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0048513//animal organ development;GO:0048536//spleen development;GO:0048645//animal organ formation;GO:0048705//skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0055123//digestive system development;GO:0060576//intestinal epithelial cell development"	Homeobox
ENSG00000109736	22.325	23.621	25.609	24.434	25.953	23.919	797	840	675	642	775	619	MFSD10	major facilitator superfamily domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16894]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031526//brush border membrane	GO:0005515//protein binding;GO:0008493//tetracycline transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006915//apoptotic process;GO:0015904//tetracycline transmembrane transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000109738	12.318	10.759	11.636	8.435	8.247	12.014	529	480	375	305	319	403	GLRB	glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05196	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016935//glycine-gated chloride channel complex;GO:0030054//cell junction;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098690//glycinergic synapse;GO:0098982//GABA-ergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0016594//glycine binding;GO:0016933//extracellularly glycine-gated ion channel activity;GO:0016934//extracellularly glycine-gated chloride channel activity;GO:0030594//neurotransmitter receptor activity;GO:0044877//protein-containing complex binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001964//startle response;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007340//acrosome reaction;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0007628//adult walking behavior;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043200//response to amino acid;GO:0050877//nervous system process;GO:0050905//neuromuscular process;GO:0060012//synaptic transmission, glycinergic;GO:0060013//righting reflex;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:1902476//chloride transmembrane transport"	--
ENSG00000109743	0.365	0.486	0.448	0.362	0.779	0.556	15	18	10	11	27	12	BST1	bone marrow stromal cell antigen 1 [Source:HGNC Symbol;Acc:HGNC:1118]	Metabolism;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko00760//Nicotinate and nicotinamide metabolism	K18152;K18152;K18152;K18152	GO:0001931//uropod;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	"GO:0003953//NAD+ nucleosidase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating;GO:0061811//ADP-ribosyl cyclase activity;GO:0061812//cyclic ADP-ribose hydrolase"	GO:0001952//regulation of cell-matrix adhesion;GO:0002691//regulation of cellular extravasation;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0030890//positive regulation of B cell proliferation;GO:0032956//regulation of actin cytoskeleton organization;GO:0050727//regulation of inflammatory response;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050848//regulation of calcium-mediated signaling;GO:0090022//regulation of neutrophil chemotaxis;GO:0090322//regulation of superoxide metabolic process;GO:2001044//regulation of integrin-mediated signaling pathway	--
ENSG00000109756	7.842	7.674	6.25	4.362	5.711	5.51	1164	1138	702	491	733	612	RAPGEF2	Rap guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:16854]	Environmental Information Processing;Environmental Information Processing;Cellular Processes	Signal transduction;Signal transduction;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04015//Rap1 signaling pathway;ko04530//Tight junction	K08018;K08018;K08018	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019992//diacylglycerol binding;GO:0030165//PDZ domain binding;GO:0030552//cAMP binding;GO:0031697//beta-1 adrenergic receptor binding;GO:0050699//WW domain binding;GO:0070300//phosphatidic acid binding	GO:0000165//MAPK cascade;GO:0001568//blood vessel development;GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0010976//positive regulation of neuron projection development;GO:0019933//cAMP-mediated signaling;GO:0021591//ventricular system development;GO:0021884//forebrain neuron development;GO:0030033//microvillus assembly;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032486//Rap protein signal transduction;GO:0035556//intracellular signal transduction;GO:0038180//nerve growth factor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043547//positive regulation of GTPase activity;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045860//positive regulation of protein kinase activity;GO:0048022//negative regulation of melanin biosynthetic process;GO:0048167//regulation of synaptic plasticity;GO:0050774//negative regulation of dendrite morphogenesis;GO:0061028//establishment of endothelial barrier;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:0071321//cellular response to cGMP;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0090557//establishment of endothelial intestinal barrier;GO:1901888//regulation of cell junction assembly;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:2001214//positive regulation of vasculogenesis;GO:2001224//positive regulation of neuron migration	--
ENSG00000109758	0.048	0.024	0	0.129	0.028	0.066	2	1	0	4	1	2	HGFAC	HGF activator [Source:HGNC Symbol;Acc:HGNC:4894]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0110165//cellular anatomical entity	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0031638//zymogen activation	--
ENSG00000109762	26.9	23.855	24.069	16.653	19.1	24.919	1901	1660	1232	874	1108	1245	SNX25	sorting nexin 25 [Source:HGNC Symbol;Acc:HGNC:21883]	-	-	-	-	GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0035091//phosphatidylinositol binding	GO:0015031//protein transport;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032801//receptor catabolic process;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation	--
ENSG00000109771	0.976	0.624	0.611	0.57	0.497	0.554	86	58	38	36	38	34	LRP2BP	LRP2 binding protein [Source:HGNC Symbol;Acc:HGNC:25434]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000109775	15.81	14.734	17.273	12.428	12.221	15.314	705.61	656.66	536.41	420.11	487.7	490.67	UFSP2	UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0071567//UFM1 hydrolase activity	GO:0006508//proteolysis;GO:0033146//regulation of intracellular estrogen receptor signaling pathway	--
ENSG00000109787	8.322	6.764	8.057	6.213	7.479	9.097	950	759	678	534	720	768	KLF3	Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15605	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:1901653//cellular response to peptide	zf-C2H2
ENSG00000109790	22.68	19.735	18.911	21.817	20.336	22.028	1449	1339	966	1065	1203	1089	KLHL5	kelch like family member 5 [Source:HGNC Symbol;Acc:HGNC:6356]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000109794	14.727	13.239	16.945	16.887	16.728	15.284	574	547	541	489	604	457	FAM149A	family with sequence similarity 149 member A [Source:HGNC Symbol;Acc:HGNC:24527]	-	-	-	-	-	-	-	--
ENSG00000109805	0.242	0.247	0.228	0.344	0.286	0.17	23.07	23.66	16.04	18.09	18.02	11.8	NCAPG	non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304]	-	-	-	-	"GO:0000779//condensed chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane"	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0030261//chromosome condensation;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000109814	11.983	9.395	13.975	9.104	7.529	7.759	458	473	379	232	306	248	UGDH	UDP-glucose 6-dehydrogenase [Source:HGNC Symbol;Acc:HGNC:12525]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00012;K00012;K00012;K00012	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0003979//UDP-glucose 6-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0051287//NAD binding"	GO:0001702//gastrulation with mouth forming second;GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006065//UDP-glucuronate biosynthetic process;GO:0008152//metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0034214//protein hexamerization;GO:0048666//neuron development	--
ENSG00000109819	15.091	14.21	12.853	13.536	12.448	12.302	1415	1286	850	784	941	1009	PPARGC1A	PPARG coactivator 1 alpha [Source:HGNC Symbol;Acc:HGNC:9237]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Environmental adaptation;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Endocrine system	ko05016//Huntington disease;ko04714//Thermogenesis;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway	K07202;K07202;K07202;K07202;K07202;K07202;K07202;K07202;K07202;K07202	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0001659//temperature homeostasis;GO:0001678//cellular glucose homeostasis;GO:0002021//response to dietary excess;GO:0006094//gluconeogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0007005//mitochondrion organization;GO:0007586//digestion;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0010822//positive regulation of mitochondrion organization;GO:0014850//response to muscle activity;GO:0019395//fatty acid oxidation;GO:0022904//respiratory electron transport chain;GO:0032922//circadian regulation of gene expression;GO:0034599//cellular response to oxidative stress;GO:0035066//positive regulation of histone acetylation;GO:0042594//response to starvation;GO:0042752//regulation of circadian rhythm;GO:0043524//negative regulation of neuron apoptotic process;GO:0045333//cellular respiration;GO:0045722//positive regulation of gluconeogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046321//positive regulation of fatty acid oxidation;GO:0048511//rhythmic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050821//protein stabilization;GO:0050873//brown fat cell differentiation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060612//adipose tissue development;GO:0065003//protein-containing complex assembly;GO:0097009//energy homeostasis;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901215//negative regulation of neuron death;GO:1901857//positive regulation of cellular respiration;GO:1901860//positive regulation of mitochondrial DNA metabolic process;GO:1901863//positive regulation of muscle tissue development;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000109832	0.943	1.199	1.048	0.868	1.234	1.108	33	43	28	26	45	29	DDX25	DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0033391//chromatoid body	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0030154//cell differentiation;GO:0051028//mRNA transport	--
ENSG00000109846	448.687	466.984	413.697	451.541	438.376	381.248	7631	7873	5172	5656	6243	4730	CRYAB	crystallin alpha B [Source:HGNC Symbol;Acc:HGNC:2389]	Genetic Information Processing;Organismal Systems	"Folding, sorting and degradation;Aging"	ko04141//Protein processing in endoplasmic reticulum;ko04213//Longevity regulating pathway - multiple species	K09542;K09542	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0015630//microtubule cytoskeleton;GO:0030018//Z disc;GO:0030424//axon;GO:0031430//M band;GO:0031674//I band;GO:0032432//actin filament bundle;GO:0032991//protein-containing complex;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043292//contractile fiber;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0097060//synaptic membrane;GO:0097512//cardiac myofibril	GO:0001540//amyloid-beta binding;GO:0005198//structural molecule activity;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	"GO:0001666//response to hypoxia;GO:0002088//lens development in camera-type eye;GO:0006457//protein folding;GO:0006936//muscle contraction;GO:0007021//tubulin complex assembly;GO:0007517//muscle organ development;GO:0007568//aging;GO:0010259//multicellular organism aging;GO:0010629//negative regulation of gene expression;GO:0010941//regulation of cell death;GO:0030308//negative regulation of cell growth;GO:0031109//microtubule polymerization or depolymerization;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032355//response to estradiol;GO:0032387//negative regulation of intracellular transport;GO:0042542//response to hydrogen peroxide;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0051403//stress-activated MAPK cascade;GO:0060561//apoptotic process involved in morphogenesis;GO:0071480//cellular response to gamma radiation;GO:1905907//negative regulation of amyloid fibril formation;GO:2000378//negative regulation of reactive oxygen species metabolic process"	--
ENSG00000109851	0	0	0	0	0	0	0	0	0	0	0	0	DBX1	developing brain homeobox 1 [Source:HGNC Symbol;Acc:HGNC:33185]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021515//cell differentiation in spinal cord;GO:0021521//ventral spinal cord interneuron specification"	Homeobox
ENSG00000109854	2.298	1.877	1.802	1.434	3.081	2.964	54	41	32	24	54	39	HTATIP2	HIV-1 Tat interactive protein 2 [Source:HGNC Symbol;Acc:HGNC:16637]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0003713//transcription coactivator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0001525//angiogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0045765//regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0051170//import into nucleus	--
ENSG00000109861	35.218	33.766	36.322	38.088	40.136	47.318	1321	1243	1013	1059	1215	1319	CTSC	cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K01275;K01275	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004197//cysteine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0016787//hydrolase activity;GO:0019902//phosphatase binding;GO:0031404//chloride ion binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0051087//chaperone binding	GO:0001913//T cell mediated cytotoxicity;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007568//aging;GO:0010033//response to organic substance;GO:0031642//negative regulation of myelination;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process;GO:1903980//positive regulation of microglial cell activation;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000109881	3.581	3.749	2.47	2.682	1.973	2.31	135	133	71	73	63	66	CCDC34	coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000109906	0.091	0.088	0.317	0.069	0.084	0.099	16	14	25	9	11	6	ZBTB16	zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:12930]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05221//Acute myeloid leukemia	K10055;K10055;K10055	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001823//mesonephros development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009952//anterior/posterior pattern specification;GO:0016567//protein ubiquitination;GO:0030097//hemopoiesis;GO:0030099//myeloid cell differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0034504//protein localization to nucleus;GO:0035116//embryonic hindlimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0043931//ossification involved in bone maturation;GO:0045600//positive regulation of fat cell differentiation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045778//positive regulation of ossification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048133//male germ-line stem cell asymmetric division;GO:0051138//positive regulation of NK T cell differentiation;GO:0051216//cartilage development;GO:0061036//positive regulation of cartilage development"	ZBTB
ENSG00000109911	11.217	9.768	8.861	9.911	9.668	11.555	531.32	437.17	311.1	301.69	360.77	403.9	ELP4	elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:1171]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0008023//transcription elongation factor complex;GO:0033588//elongator holoenzyme complex	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0008607//phosphorylase kinase regulator activity	GO:0002098//tRNA wobble uridine modification;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006417//regulation of translation;GO:0008033//tRNA processing;GO:0050790//regulation of catalytic activity	--
ENSG00000109917	11.558	10.272	9.526	9.957	14.012	9.953	558	546	363	370	443	360	ZPR1	ZPR1 zinc finger [Source:HGNC Symbol;Acc:HGNC:13051]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm;GO:0097504//Gemini of coiled bodies	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030971//receptor tyrosine kinase binding;GO:0031369//translation initiation factor binding;GO:0046872//metal ion binding	GO:0000226//microtubule cytoskeleton organization;GO:0001833//inner cell mass cell proliferation;GO:0001834//trophectodermal cell proliferation;GO:0006397//mRNA processing;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0021510//spinal cord development;GO:0030154//cell differentiation;GO:0030576//Cajal body organization;GO:0031641//regulation of myelination;GO:0033120//positive regulation of RNA splicing;GO:0042023//DNA endoreduplication;GO:0042307//positive regulation of protein import into nucleus;GO:0045787//positive regulation of cell cycle;GO:0045927//positive regulation of growth;GO:0061564//axon development;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071931//positive regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:1902742//apoptotic process involved in development;GO:1990261//pre-mRNA catabolic process;GO:2000672//negative regulation of motor neuron apoptotic process	--
ENSG00000109919	42.2	39.004	39.024	39.256	37.539	39.578	1897	1778	1289	1327	1413	1293	MTCH2	mitochondrial carrier 2 [Source:HGNC Symbol;Acc:HGNC:17587]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0010635//regulation of mitochondrial fusion;GO:0043065//positive regulation of apoptotic process;GO:0055088//lipid homeostasis;GO:0070585//protein localization to mitochondrion;GO:2000738//positive regulation of stem cell differentiation	--
ENSG00000109920	7.396	5.633	5.533	4.659	5.848	7.16	619	443	342	260	384	436	FNBP4	formin binding protein 4 [Source:HGNC Symbol;Acc:HGNC:19752]	-	-	-	-	GO:0016607//nuclear speck	GO:0005515//protein binding	-	--
ENSG00000109927	0.195	0.149	0.254	0.082	0.235	0.093	29	21	23.71	9	24	10	TECTA	tectorin alpha [Source:HGNC Symbol;Acc:HGNC:11720]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0007160//cell-matrix adhesion;GO:0007605//sensory perception of sound	--
ENSG00000109929	49.051	42.663	43.729	44.422	43.659	55.049	2715	2228	1807	1765	2046	2154	SC5D	sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K00227;K00227	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000248//C-5 sterol desaturase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0050046//delta7-sterol 5(6)-desaturase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008610//lipid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0033490//cholesterol biosynthetic process via lathosterol	--
ENSG00000109943	0	0	0	0	0	0	0	0	0	0	0	0	CRTAM	cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313]	-	-	-	-	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0001768//establishment of T cell polarity;GO:0001819//positive regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002355//detection of tumor cell;GO:0002376//immune system process;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0008037//cell recognition;GO:0032729//positive regulation of interferon-gamma production;GO:0045580//regulation of T cell differentiation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046007//negative regulation of activated T cell proliferation;GO:0050863//regulation of T cell activation;GO:0051606//detection of stimulus;GO:0097021//lymphocyte migration into lymphoid organs;GO:2001185//regulation of CD8-positive, alpha-beta T cell activation"	--
ENSG00000109944	4.825	3.697	4.661	2.77	2.669	3.48	422	297	219	135	156	175	JHY	junctional cadherin complex regulator [Source:HGNC Symbol;Acc:HGNC:26288]	-	-	-	-	GO:0005576//extracellular region	-	GO:0007420//brain development;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0035082//axoneme assembly;GO:0044458//motile cilium assembly;GO:0090175//regulation of establishment of planar polarity;GO:0090660//cerebrospinal fluid circulation	--
ENSG00000109956	11.232	11.283	12.93	13.314	14.144	14.892	891	882	752	782	940	834	B3GAT1	"beta-1,3-glucuronyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:921]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K00735;K00735	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process	--
ENSG00000109971	736.492	729.528	722.407	649.4	657.024	585.686	34431	34398	24980	22566	26000	19922	HSPA8	heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0000974//Prp19 complex;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030425//dendrite;GO:0034774//secretory granule lumen;GO:0042470//melanosome;GO:0043195//terminal bouton;GO:0043202//lysosomal lumen;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098575//lumenal side of lysosomal membrane;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol;GO:0101031//chaperone complex;GO:1904813//ficolin-1-rich granule lumen;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0023026//MHC class II protein complex binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0045296//cadherin binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0140545//protein disaggregase activity;GO:0140597//protein carrier activity;GO:1990833//clathrin-uncoating ATPase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0008380//RNA splicing;GO:0009267//cellular response to starvation;GO:0016192//vesicle-mediated transport;GO:0031647//regulation of protein stability;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0043254//regulation of protein-containing complex assembly;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046034//ATP metabolic process;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0061024//membrane organization;GO:0061635//regulation of protein complex stability;GO:0061684//chaperone-mediated autophagy;GO:0061738//late endosomal microautophagy;GO:0061740//protein targeting to lysosome involved in chaperone-mediated autophagy;GO:0071383//cellular response to steroid hormone stimulus;GO:1902904//negative regulation of supramolecular fiber organization;GO:1904589//regulation of protein import;GO:1904764//chaperone-mediated autophagy translocation complex disassembly;GO:1990832//slow axonal transport"	--
ENSG00000109991	0	0	0	0.017	0	0	0	0	0	1	0	0	P2RX3	purinergic receptor P2X 3 [Source:HGNC Symbol;Acc:HGNC:8534]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04742//Taste transduction	K05217;K05217;K05217	GO:0005639//integral component of nuclear inner membrane;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0099056//integral component of presynaptic membrane	GO:0000166//nucleotide binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005216//ion channel activity;GO:0005524//ATP binding;GO:0042802//identical protein binding	GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0009266//response to temperature stimulus;GO:0009408//response to heat;GO:0009409//response to cold;GO:0009612//response to mechanical stimulus;GO:0009743//response to carbohydrate;GO:0010033//response to organic substance;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0014832//urinary bladder smooth muscle contraction;GO:0019228//neuronal action potential;GO:0030432//peristalsis;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0048266//behavioral response to pain;GO:0050804//modulation of chemical synaptic transmission;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050909//sensory perception of taste;GO:0060079//excitatory postsynaptic potential;GO:0061368//behavioral response to formalin induced pain;GO:0070207//protein homotrimerization;GO:0071318//cellular response to ATP;GO:0098655//cation transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:1904058//positive regulation of sensory perception of pain	--
ENSG00000110002	19.064	19.602	18.335	14.102	13.973	15.704	1093	1165	818	654	720	653	VWA5A	von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000110011	27.183	30.08	29.16	34.756	32.924	27.906	627	684	496	591	647	465.87	DNAJC4	DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein	--
ENSG00000110013	21.724	23.698	22.875	21.716	22.24	22.103	1547.04	1642.61	1177.74	1115.23	1271.4	1130.98	SIAE	sialic acid acetylesterase [Source:HGNC Symbol;Acc:HGNC:18187]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0070062//extracellular exosome	GO:0001681//sialate O-acetylesterase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0106330//sialate 9-O-acetylesterase activity;GO:0106331//sialate 4-O-acetylesterase activity	GO:0002682//regulation of immune system process;GO:0005975//carbohydrate metabolic process	--
ENSG00000110025	10.63	11.883	11.523	11.666	12.409	11.411	415	422	314	342	395	298	SNX15	sorting nexin 15 [Source:HGNC Symbol;Acc:HGNC:14978]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000110031	1.237	1.481	1	1.593	2.15	1.411	48	58	28	46	70	40	LPXN	leupaxin [Source:HGNC Symbol;Acc:HGNC:14061]	-	-	-	-	GO:0002102//podosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043542//endothelial cell migration;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0065003//protein-containing complex assembly"	--
ENSG00000110042	16.47	15.649	18.713	17.924	18.497	19.635	1700	1561	1489	1417	1645	1484	DTX4	deltex E3 ubiquitin ligase 4 [Source:HGNC Symbol;Acc:HGNC:29151]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06058	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination;GO:0032479//regulation of type I interferon production	--
ENSG00000110046	6.674	7.795	8.11	7.099	8.638	6.868	868	950	753	672	935	629	ATG2A	autophagy related 2A [Source:HGNC Symbol;Acc:HGNC:29028]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04136//Autophagy - other	K17906;K17906;K17906;K17906;K17906;K17906;K17906	GO:0000407//phagophore assembly site;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0034045//phagophore assembly site membrane;GO:0044232//organelle membrane contact site	GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0120013//lipid transfer activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0034727//piecemeal microautophagy of the nucleus;GO:0044805//late nucleophagy;GO:0061709//reticulophagy;GO:0120009//intermembrane lipid transfer;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000110047	24.539	21.365	25.052	27.453	30.597	27.147	1588	1603	1241	1502	1639	1249	EHD1	EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12483	GO:0005768//endosome;GO:0005769//early endosome;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0020018//ciliary pocket membrane;GO:0030139//endocytic vesicle;GO:0031095//platelet dense tubular network membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0010886//positive regulation of cholesterol storage;GO:0010976//positive regulation of neuron projection development;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030030//cell projection organization;GO:0031175//neuron projection development;GO:0032456//endocytic recycling;GO:0034383//low-density lipoprotein particle clearance;GO:0042632//cholesterol homeostasis;GO:0051260//protein homooligomerization;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0072659//protein localization to plasma membrane;GO:0120036//plasma membrane bounded cell projection organization;GO:1901741//positive regulation of myoblast fusion;GO:1990090//cellular response to nerve growth factor stimulus;GO:2001137//positive regulation of endocytic recycling	--
ENSG00000110048	20.081	19.573	19.346	16.227	17.16	16.323	1930	1911	1381	1175	1416	1161	OSBP	oxysterol binding protein [Source:HGNC Symbol;Acc:HGNC:8503]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0008142//oxysterol binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0019904//protein domain specific binding;GO:0032934//sterol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0120015//sterol transfer activity	GO:0006686//sphingomyelin biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0032367//intracellular cholesterol transport;GO:0035627//ceramide transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0120009//intermembrane lipid transfer;GO:1904411//positive regulation of secretory granule organization	--
ENSG00000110057	7.734	8.196	8.508	11.718	11.294	8.81	368	392	299	413	454	305	UNC93B1	"unc-93 homolog B1, TLR signaling regulator [Source:HGNC Symbol;Acc:HGNC:13481]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032009//early phagosome;GO:0045335//phagocytic vesicle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0035325//Toll-like receptor binding	GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006886//intracellular protein transport;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000110060	8.209	5.28	5.54	6.175	5.407	7.837	202	134	103	106	112	149	PUS3	pseudouridine synthase 3 [Source:HGNC Symbol;Acc:HGNC:25461]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0106029//tRNA pseudouridine synthase activity	GO:0001522//pseudouridine synthesis;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0031119//tRNA pseudouridine synthesis;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000110063	9.891	9.959	12.022	12.281	11.187	11.777	629	668.02	511	518	568	507	DCPS	"decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12584	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000340//RNA 7-methylguanosine cap binding;GO:0004532//exoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0050072//m7G(5')pppN diphosphatase activity	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036245//cellular response to menadione;GO:0043069//negative regulation of programmed cell death;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045292//mRNA cis splicing, via spliceosome;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0110156//methylguanosine-cap decapping"	--
ENSG00000110066	12.733	9.637	10.552	8.722	9.99	10.01	965	806	579	508	633	562	KMT5B	lysine methyltransferase 5B [Source:HGNC Symbol;Acc:HGNC:24283]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11429;K11429	"GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0046872//metal ion binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0007517//muscle organ development;GO:0016571//histone methylation;GO:0032259//methylation;GO:0034770//histone H4-K20 methylation;GO:0034772//histone H4-K20 dimethylation;GO:0034773//histone H4-K20 trimethylation;GO:0034968//histone lysine methylation;GO:0045830//positive regulation of isotype switching;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000110074	8.821	9.952	10.959	10.846	11.086	11.665	357	409	327	325	379	345	FOXRED1	FAD dependent oxidoreductase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26927]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0016491//oxidoreductase activity	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000110075	23.4	17.733	20.182	12.337	15.052	18.516	1710	1376	1190	765	975	1072	PPP6R3	protein phosphatase 6 regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:1173]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding	GO:0006516//glycoprotein catabolic process;GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000110076	0.436	0.285	0.406	0.564	0.57	0.892	32	21	22	23	32	43	NRXN2	neurexin 2 [Source:HGNC Symbol;Acc:HGNC:8009]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07377	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0098793//presynapse	GO:0004888//transmembrane signaling receptor activity;GO:0005246//calcium channel regulator activity;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0097109//neuroligin family protein binding	GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007416//synapse assembly;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0042297//vocal learning;GO:0071625//vocalization behavior;GO:0097104//postsynaptic membrane assembly;GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0097118//neuroligin clustering involved in postsynaptic membrane assembly;GO:0097119//postsynaptic density protein 95 clustering	--
ENSG00000110077	0.075	0.246	0.051	0.165	0.318	0.383	2	4	1	2	7	5	MS4A6A	membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375]	-	-	-	-	GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000110079	0	0	0	0	0.096	0	0	0	0	0	2	0	MS4A4A	membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044853//plasma membrane raft	GO:0005515//protein binding	-	--
ENSG00000110080	201.275	204.139	214.196	291.517	254.1	344.631	6300	6291	5006	6878	6635	7899	ST3GAL4	"ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K03494;K03494	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0004513//neolactotetraosylceramide alpha-2,3-sialyltransferase activity;GO:0008118//N-acetyllactosaminide alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047288//monosialoganglioside sialyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0009247//glycolipid biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0019082//viral protein processing;GO:0030194//positive regulation of blood coagulation;GO:0030259//lipid glycosylation;GO:0050890//cognition;GO:0097503//sialylation;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:1990743//protein sialylation	--
ENSG00000110090	12.528	13.12	18.839	21.725	21.564	20.083	1069	1164	1209	1382	1570	1304	CPT1A	carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328]	Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Environmental adaptation;Endocrine and metabolic disease;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism	ko04714//Thermogenesis;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K08765;K08765;K08765;K08765;K08765;K08765;K08765;K08765;K08765	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004095//carnitine O-palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding;GO:1990698//palmitoleoyltransferase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006006//glucose metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006641//triglyceride metabolic process;GO:0006853//carnitine shuttle;GO:0009410//response to xenobiotic stimulus;GO:0009437//carnitine metabolic process;GO:0010876//lipid localization;GO:0010883//regulation of lipid storage;GO:0014070//response to organic cyclic compound;GO:0030855//epithelial cell differentiation;GO:0031667//response to nutrient levels;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0042755//eating behavior;GO:0043279//response to alkaloid;GO:0045471//response to ethanol;GO:0046320//regulation of fatty acid oxidation;GO:0046677//response to antibiotic;GO:0050796//regulation of insulin secretion;GO:0071398//cellular response to fatty acid;GO:0097421//liver regeneration;GO:1904772//response to tetrachloromethane	--
ENSG00000110092	73.33	71.415	70.376	92.822	95.682	83.303	6446	6309.98	4569	6014	7105.98	5328	CCND1	cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Signal transduction;Cancer: specific types;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Endocrine system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Signal transduction;Cardiovascular disease;Cell growth and death;Endocrine system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Signal transduction;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04530//Tight junction;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko04936//Alcoholic liver disease;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko05416//Viral myocarditis;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05221//Acute myeloid leukemia;ko05213//Endometrial cancer;ko04340//Hedgehog signaling pathway;ko05219//Bladder cancer;ko05216//Thyroid cancer	K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503;K04503	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0017053//transcription repressor complex;GO:0031965//nuclear membrane;GO:0097128//cyclin D1-CDK4 complex	GO:0003714//transcription corepressor activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0042826//histone deacetylase binding;GO:0044877//protein-containing complex binding;GO:0070064//proline-rich region binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000320//re-entry into mitotic cell cycle;GO:0001889//liver development;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010039//response to iron ion;GO:0010165//response to X-ray;GO:0010243//response to organonitrogen compound;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014070//response to organic cyclic compound;GO:0016055//Wnt signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031100//animal organ regeneration;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0032026//response to magnesium ion;GO:0032355//response to estradiol;GO:0033197//response to vitamin E;GO:0033327//Leydig cell differentiation;GO:0033598//mammary gland epithelial cell proliferation;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0043627//response to estrogen;GO:0044321//response to leptin;GO:0044772//mitotic cell cycle phase transition;GO:0045444//fat cell differentiation;GO:0045471//response to ethanol;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048545//response to steroid hormone;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051384//response to glucocorticoid;GO:0051412//response to corticosterone;GO:0051592//response to calcium ion;GO:0051726//regulation of cell cycle;GO:0060749//mammary gland alveolus development;GO:0070141//response to UV-A;GO:0071310//cellular response to organic substance;GO:0097421//liver regeneration;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000110104	11.044	12.905	12.378	12.518	11.993	12.243	424	498	351	356	389	342	CCDC86	coiled-coil domain containing 86 [Source:HGNC Symbol;Acc:HGNC:28359]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000110107	42.355	40.557	42.863	43.416	43.144	44.86	1731	1796	1336	1476	1590	1378	PRPF19	pre-mRNA processing factor 19 [Source:HGNC Symbol;Acc:HGNC:17896]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Transcription"	ko04120//Ubiquitin mediated proteolysis;ko03040//Spliceosome	K10599;K10599	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0035861//site of double-strand break;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0042802//identical protein binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000209//protein polyubiquitination;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0008610//lipid biosynthetic process;GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0034613//cellular protein localization;GO:0045666//positive regulation of neuron differentiation;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0048711//positive regulation of astrocyte differentiation;GO:0070534//protein K63-linked ubiquitination"	--
ENSG00000110108	93.796	97.146	106.332	120.176	112.575	114.781	4142	4312	3468	3931	4200	3688	TMEM109	transmembrane protein 109 [Source:HGNC Symbol;Acc:HGNC:28771]	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0060548//negative regulation of cell death;GO:0071480//cellular response to gamma radiation	--
ENSG00000110148	0.056	0.028	0.165	0.082	0.099	0.038	2	1	2	1	3	1	CCKBR	cholecystokinin B receptor [Source:HGNC Symbol;Acc:HGNC:1571]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04971//Gastric acid secretion	K04195;K04195;K04195	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004951//cholecystokinin receptor activity;GO:0005515//protein binding;GO:0015054//gastrin receptor activity;GO:0017046//peptide hormone binding;GO:0031741//type B gastrin/cholecystokinin receptor binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0001696//gastric acid secretion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell population proliferation;GO:0038188//cholecystokinin signaling pathway;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045851//pH reduction;GO:0048565//digestive tract development;GO:0048732//gland development	--
ENSG00000110169	0	0.122	0	0	0.072	0	0	4	0	0	2	0	HPX	hemopexin [Source:HGNC Symbol;Acc:HGNC:5171]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle	GO:0005515//protein binding;GO:0015232//heme transmembrane transporter activity;GO:0046872//metal ion binding	GO:0002639//positive regulation of immunoglobulin production;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006879//cellular iron ion homeostasis;GO:0015886//heme transport;GO:0020027//hemoglobin metabolic process;GO:0042168//heme metabolic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0051246//regulation of protein metabolic process;GO:0060332//positive regulation of response to interferon-gamma;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway	--
ENSG00000110171	3.519	3.9	3.632	3.867	3.491	3.227	181	221	160	170	174	140	TRIM3	tripartite motif containing 3 [Source:HGNC Symbol;Acc:HGNC:10064]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0042995//cell projection	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0007399//nervous system development;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000110172	27.3	27.24	27.292	19.08	23.49	25.121	875	802	601	451	616	560	CHORDC1	cysteine and histidine rich domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14525]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding	GO:0010824//regulation of centrosome duplication;GO:0051298//centrosome duplication;GO:0061077//chaperone-mediated protein folding;GO:1900034//regulation of cellular response to heat;GO:2000299//negative regulation of Rho-dependent protein serine/threonine kinase activity	--
ENSG00000110195	73.313	82.821	80.855	51.316	53.478	55.245	1643	1854	1327	847	1010	901	FOLR1	folate receptor alpha [Source:HGNC Symbol;Acc:HGNC:3791]	Cellular Processes;Human Diseases	Transport and catabolism;Drug resistance: antineoplastic	ko04144//Endocytosis;ko01523//Antifolate resistance	K13649;K13649	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030133//transport vesicle;GO:0030136//clathrin-coated vesicle;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0038023//signaling receptor activity;GO:0061714//folic acid receptor activity	GO:0001947//heart looping;GO:0003147//neural crest cell migration involved in heart formation;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006898//receptor-mediated endocytosis;GO:0007155//cell adhesion;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0015884//folic acid transport;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0031103//axon regeneration;GO:0035036//sperm-egg recognition;GO:0046655//folic acid metabolic process;GO:0048678//response to axon injury;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061626//pharyngeal arch artery morphogenesis;GO:0061713//anterior neural tube closure;GO:0071231//cellular response to folic acid;GO:1904447//folate import across plasma membrane	--
ENSG00000110200	17.737	17.356	18.488	19.84	16.693	17.571	305.85	305.53	236.87	251.91	236.93	222.9	ANAPC15	anaphase promoting complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:24531]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K25228;K25228;K25228;K25228;K25228	GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint	--
ENSG00000110203	0	0	0	0	0	0	0	0	0	0	0	0	FOLR3	folate receptor gamma [Source:HGNC Symbol;Acc:HGNC:3795]	Cellular Processes;Human Diseases	Transport and catabolism;Drug resistance: antineoplastic	ko04144//Endocytosis;ko01523//Antifolate resistance	K13649;K13649	GO:0005576//extracellular region;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0038023//signaling receptor activity	GO:0007155//cell adhesion;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0015884//folic acid transport;GO:0035036//sperm-egg recognition	--
ENSG00000110218	7.793	6.492	5.493	6.139	5.022	6.25	461	386	240	269	251	269	PANX1	pannexin 1 [Source:HGNC Symbol;Acc:HGNC:8599]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K03443	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032059//bleb;GO:0032991//protein-containing complex	GO:0002020//protease binding;GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005243//gap junction channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015267//channel activity;GO:0022829//wide pore channel activity;GO:0022840//leak channel activity;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding;GO:0097110//scaffold protein binding	GO:0001819//positive regulation of cytokine production;GO:0002931//response to ischemia;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0007267//cell-cell signaling;GO:0030154//cell differentiation;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032732//positive regulation of interleukin-1 production;GO:0033198//response to ATP;GO:0048477//oogenesis;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000110237	14.919	16.627	18.527	15.947	17.056	17.543	2526	2798	2195	1941	2401	2074	ARHGEF17	Rho guanine nucleotide exchange factor 17 [Source:HGNC Symbol;Acc:HGNC:21726]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0030036//actin cytoskeleton organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000110243	0	0	0	0.069	0	0	0	0	0	2	0	0	APOA5	apolipoprotein A5 [Source:HGNC Symbol;Acc:HGNC:17288]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K09025	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008047//enzyme activator activity;GO:0008201//heparin binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0031210//phosphatidylcholine binding;GO:0035473//lipase binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0060229//lipase activator activity;GO:0060230//lipoprotein lipase activator activity;GO:0070325//lipoprotein particle receptor binding	GO:0006641//triglyceride metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006869//lipid transport;GO:0010873//positive regulation of cholesterol esterification;GO:0010898//positive regulation of triglyceride catabolic process;GO:0010902//positive regulation of very-low-density lipoprotein particle remodeling;GO:0019433//triglyceride catabolic process;GO:0030300//regulation of intestinal cholesterol absorption;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034380//high-density lipoprotein particle assembly;GO:0042157//lipoprotein metabolic process;GO:0042246//tissue regeneration;GO:0042632//cholesterol homeostasis;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050996//positive regulation of lipid catabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0055090//acylglycerol homeostasis;GO:0070328//triglyceride homeostasis	--
ENSG00000110244	0	0	0	0	0	0	0	0	0	0	0	0	APOA4	apolipoprotein A4 [Source:HGNC Symbol;Acc:HGNC:602]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cardiovascular disease;Digestive system;Digestive system;Digestive system	ko05417//Lipid and atherosclerosis;ko04979//Cholesterol metabolism;ko04975//Fat digestion and absorption;ko04977//Vitamin digestion and absorption	K08760;K08760;K08760;K08760	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0009986//cell surface;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005319//lipid transporter activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0016209//antioxidant activity;GO:0031210//phosphatidylcholine binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0120020//cholesterol transfer activity	GO:0002227//innate immune response in mucosa;GO:0006695//cholesterol biosynthetic process;GO:0006869//lipid transport;GO:0006982//response to lipid hydroperoxide;GO:0007159//leukocyte cell-cell adhesion;GO:0008203//cholesterol metabolic process;GO:0010873//positive regulation of cholesterol esterification;GO:0010898//positive regulation of triglyceride catabolic process;GO:0014012//peripheral nervous system axon regeneration;GO:0016042//lipid catabolic process;GO:0019430//removal of superoxide radicals;GO:0030300//regulation of intestinal cholesterol absorption;GO:0032374//regulation of cholesterol transport;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034014//response to triglyceride;GO:0034371//chylomicron remodeling;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034378//chylomicron assembly;GO:0034380//high-density lipoprotein particle assembly;GO:0034445//negative regulation of plasma lipoprotein oxidation;GO:0035634//response to stilbenoid;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0042744//hydrogen peroxide catabolic process;GO:0043691//reverse cholesterol transport;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0055088//lipid homeostasis;GO:0065005//protein-lipid complex assembly;GO:0070328//triglyceride homeostasis;GO:0120009//intermembrane lipid transfer	--
ENSG00000110245	0	0	0	0	0	0	0	0	0	0	0	0	APOC3	apolipoprotein C3 [Source:HGNC Symbol;Acc:HGNC:610]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism	K08759;K08759	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0034361//very-low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0042627//chylomicron;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0030234//enzyme regulator activity;GO:0055102//lipase inhibitor activity;GO:0070653//high-density lipoprotein particle receptor binding	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010897//negative regulation of triglyceride catabolic process;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0010987//negative regulation of high-density lipoprotein particle clearance;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034382//chylomicron remnant clearance;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045833//negative regulation of lipid metabolic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0050995//negative regulation of lipid catabolic process;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0060621//negative regulation of cholesterol import;GO:0070328//triglyceride homeostasis	--
ENSG00000110274	9.529	9.662	10.857	9.852	12.236	12.713	704	705	550	645	720	582	CEP164	centrosomal protein 164 [Source:HGNC Symbol;Acc:HGNC:29182]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0097539//ciliary transition fiber	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0030030//cell projection organization;GO:0051301//cell division;GO:0060271//cilium assembly	--
ENSG00000110315	18.878	18.3	17.132	15.107	16.151	16.476	1474	1351	977	847	959	866	RNF141	ring finger protein 141 [Source:HGNC Symbol;Acc:HGNC:21159]	-	-	-	-	GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0051865//protein autoubiquitination"	--
ENSG00000110318	0.675	0.406	0.176	0.169	0.281	0.126	86	52	19	16	27	10	CEP126	centrosomal protein 126 [Source:HGNC Symbol;Acc:HGNC:29264]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0005515//protein binding	GO:0007052//mitotic spindle organization;GO:0030030//cell projection organization;GO:0031122//cytoplasmic microtubule organization;GO:0060271//cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000110321	330.464	308.966	276.541	234.473	257.844	257.794	24794	23269	15318	13060	16375	14145	EIF4G2	eukaryotic translation initiation factor 4 gamma 2 [Source:HGNC Symbol;Acc:HGNC:3297]	Human Diseases	Cardiovascular disease	ko05416//Viral myocarditis	K03260	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0030424//axon	"GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0045296//cadherin binding"	"GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0007507//heart development;GO:0008219//cell death;GO:0010507//negative regulation of autophagy;GO:0030307//positive regulation of cell growth;GO:0034645//cellular macromolecule biosynthetic process;GO:0045727//positive regulation of translation;GO:0045773//positive regulation of axon extension;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0060999//positive regulation of dendritic spine development"	--
ENSG00000110324	0.013	0	0	0	0.047	0	1	0	0	0	3	0	IL10RA	interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Infectious disease: parasitic;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko04630//JAK-STAT signaling pathway;ko05145//Toxoplasmosis;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05134;K05134;K05134;K05134;K05134;K05134	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004920//interleukin-10 receptor activity;GO:0005515//protein binding;GO:0019969//interleukin-10 binding;GO:0038023//signaling receptor activity	GO:0010507//negative regulation of autophagy;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050807//regulation of synapse organization;GO:0070086//ubiquitin-dependent endocytosis	--
ENSG00000110328	5.201	6.784	4.616	4.161	4.218	2.938	270	354	177	160	185	111	GALNT18	polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation	--
ENSG00000110330	11.024	7.579	7.962	6.424	7.246	8.685	723	578	408	347	440	462	BIRC2	baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	"Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Signal transduction;Cell growth and death;Signal transduction;Folding, sorting and degradation;Cell growth and death;Signal transduction;Infectious disease: parasitic;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05132//Salmonella infection;ko04510//Focal adhesion;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04390//Hippo signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko01524//Platinum drug resistance;ko04215//Apoptosis - multiple species	K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060;K16060	GO:0001741//XY body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0032991//protein-containing complex;GO:0035631//CD40 receptor complex;GO:0045121//membrane raft	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0061630//ubiquitin protein ligase activity;GO:0098770//FBXO family protein binding	"GO:0000209//protein polyubiquitination;GO:0001666//response to hypoxia;GO:0001890//placenta development;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010243//response to organonitrogen compound;GO:0014070//response to organic cyclic compound;GO:0031398//positive regulation of protein ubiquitination;GO:0032268//regulation of cellular protein metabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0038061//NIK/NF-kappaB signaling;GO:0039535//regulation of RIG-I signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043067//regulation of programmed cell death;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045088//regulation of innate immune response;GO:0045471//response to ethanol;GO:0045595//regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050727//regulation of inflammatory response;GO:0051591//response to cAMP;GO:0051726//regulation of cell cycle;GO:0052548//regulation of endopeptidase activity;GO:0060544//regulation of necroptotic process;GO:0060546//negative regulation of necroptotic process;GO:0070266//necroptotic process;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1902443//negative regulation of ripoptosome assembly involved in necroptotic process;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1902524//positive regulation of protein K48-linked ubiquitination;GO:1902527//positive regulation of protein monoubiquitination;GO:1902916//positive regulation of protein polyubiquitination;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:2000377//regulation of reactive oxygen species metabolic process"	--
ENSG00000110344	14.54	13.338	13.349	10.124	12.783	13.235	1836	1693	1245	947	1356	1216	UBE4A	ubiquitination factor E4A [Source:HGNC Symbol;Acc:HGNC:12499]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10596	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0044267//cellular protein metabolic process	--
ENSG00000110367	32.853	34.368	29.646	22.963	27.649	29.227	3556	3379	2311	1680	2272	2244	DDX6	DEAD-box helicase 6 [Source:HGNC Symbol;Acc:HGNC:2747]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12614	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019904//protein domain specific binding;GO:0045296//cadherin binding	GO:0017148//negative regulation of translation;GO:0019074//viral RNA genome packaging;GO:0019827//stem cell population maintenance;GO:0033962//P-body assembly;GO:0034063//stress granule assembly;GO:0045665//negative regulation of neuron differentiation;GO:1905618//positive regulation of miRNA mediated inhibition of translation	--
ENSG00000110375	0.155	0	0.21	0.07	0.244	0.213	3	0	3	1	4	3	UPK2	uroplakin 2 [Source:HGNC Symbol;Acc:HGNC:12579]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0030855//epithelial cell differentiation	--
ENSG00000110395	3.949	3.75	3.631	2.788	3.472	4.375	870	804	604	420	625	654	CBL	Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541]	Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases	"Cancer: overview;Transport and catabolism;Cancer: overview;Folding, sorting and degradation;Endocrine system;Signal transduction;Infectious disease: bacterial;Cancer: specific types"	ko05200//Pathways in cancer;ko04144//Endocytosis;ko05205//Proteoglycans in cancer;ko04120//Ubiquitin mediated proteolysis;ko04910//Insulin signaling pathway;ko04012//ErbB signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05220//Chronic myeloid leukemia	K04707;K04707;K04707;K04707;K04707;K04707;K04707;K04707	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0016020//membrane;GO:0016600//flotillin complex;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0001784//phosphotyrosine residue binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0046875//ephrin receptor binding;GO:0047690//aspartyltransferase activity;GO:0061630//ubiquitin protein ligase activity;GO:1990782//protein tyrosine kinase binding	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0008584//male gonad development;GO:0010332//response to gamma radiation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway;GO:0023051//regulation of signaling;GO:0032487//regulation of Rap protein signal transduction;GO:0033574//response to testosterone;GO:0035635//entry of bacterium into host cell;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042594//response to starvation;GO:0043066//negative regulation of apoptotic process;GO:0043303//mast cell degranulation;GO:0045471//response to ethanol;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0046677//response to antibiotic;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0051865//protein autoubiquitination;GO:0070997//neuron death;GO:0090650//cellular response to oxygen-glucose deprivation;GO:1901215//negative regulation of neuron death;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000583//regulation of platelet-derived growth factor receptor-alpha signaling pathway	--
ENSG00000110400	13.432	17.461	16.813	18.761	19.691	19.248	1322	1442	1166	1332	1614	1289	NECTIN1	nectin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:9706]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: viral;Signaling molecules and interaction;Cellular community - eukaryotes	ko05168//Herpes simplex virus 1 infection;ko04514//Cell adhesion molecules;ko04520//Adherens junction	K06081;K06081;K06081	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0032584//growth cone membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0044291//cell-cell contact zone;GO:0045202//synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0099059//integral component of presynaptic active zone membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046790//virion binding;GO:0050839//cell adhesion molecule binding	GO:0002089//lens morphogenesis in camera-type eye;GO:0002934//desmosome organization;GO:0006826//iron ion transport;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007411//axon guidance;GO:0019062//virion attachment to host cell;GO:0046718//viral entry into host cell;GO:0048593//camera-type eye morphogenesis;GO:0051963//regulation of synapse assembly;GO:0060041//retina development in camera-type eye;GO:0070166//enamel mineralization;GO:0098609//cell-cell adhesion;GO:1902414//protein localization to cell junction	--
ENSG00000110422	26.515	21.438	20.59	15.808	18.184	22.265	3733	2967	2234	1755	2019	2258	HIPK3	homeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:4915]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K08826	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0016605//PML body	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0009299//mRNA transcription;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0043508//negative regulation of JUN kinase activity	--
ENSG00000110427	0.056	0.047	0.042	0	0	0	9	5	3	0	0	0	KIAA1549L	KIAA1549 like [Source:HGNC Symbol;Acc:HGNC:24836]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000110429	14.864	12.671	13.809	11.65	11.308	14.734	850	754	597	477	560	624	FBXO3	F-box protein 3 [Source:HGNC Symbol;Acc:HGNC:13582]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0006508//proteolysis;GO:0016567//protein ubiquitination	--
ENSG00000110435	7.786	6.591	7.571	6.192	6.186	7.507	398	331	282	232	271	277	PDHX	pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]	Metabolism	Global and overview maps	ko01100//Metabolic pathways	K13997	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0045254//pyruvate dehydrogenase complex;GO:1990204//oxidoreductase complex	GO:0005515//protein binding;GO:0016746//acyltransferase activity;GO:0034604//pyruvate dehydrogenase (NAD+) activity	GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0044281//small molecule metabolic process;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate	--
ENSG00000110436	0	0	0.057	0	0	0	0	0	2	0	0	0	SLC1A2	solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Nervous system;Nervous system	ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle	K05613;K05613;K05613;K05613	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030673//axolemma;GO:0031982//vesicle;GO:0044297//cell body;GO:0044306//neuron projection terminus;GO:0045121//membrane raft;GO:0045202//synapse;GO:0097449//astrocyte projection;GO:0098796//membrane protein complex;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0005515//protein binding;GO:0008509//anion transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0033229//cysteine transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006750//glutathione biosynthetic process;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007632//visual behavior;GO:0009410//response to xenobiotic stimulus;GO:0009416//response to light stimulus;GO:0009611//response to wounding;GO:0010259//multicellular organism aging;GO:0015711//organic anion transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015813//L-glutamate transmembrane transport;GO:0021537//telencephalon development;GO:0030534//adult behavior;GO:0031668//cellular response to extracellular stimulus;GO:0035264//multicellular organism growth;GO:0043200//response to amino acid;GO:0046326//positive regulation of glucose import;GO:0055085//transmembrane transport;GO:0070207//protein homotrimerization;GO:0070633//transepithelial transport;GO:0070778//L-aspartate transmembrane transport;GO:0070779//D-aspartate import across plasma membrane;GO:0071314//cellular response to cocaine;GO:0098656//anion transmembrane transport;GO:0098712//L-glutamate import across plasma membrane;GO:0098810//neurotransmitter reuptake;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903712//cysteine transmembrane transport	--
ENSG00000110442	26.331	30.632	28.258	31.563	26.629	28.062	739	830	547	645	647	571	COMMD9	COMM domain containing 9 [Source:HGNC Symbol;Acc:HGNC:25014]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0042632//cholesterol homeostasis	--
ENSG00000110446	4.743	5.607	6.954	3.762	5.549	6.093	166	195	180	107	153	148	SLC15A3	solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015333//peptide:proton symporter activity;GO:0015647//peptidoglycan transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0071916//dipeptide transmembrane transporter activity	GO:0002376//immune system process;GO:0006811//ion transport;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0015835//peptidoglycan transport;GO:0045087//innate immune response;GO:0055085//transmembrane transport;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0140206//dipeptide import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000110448	0	0	0	0	0	0	0	0	0	0	0	0	CD5	CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06455	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006897//endocytosis;GO:0008037//cell recognition;GO:0031295//T cell costimulation;GO:0097190//apoptotic signaling pathway	--
ENSG00000110455	2.792	2.999	3.536	3.817	3.845	4.101	138	149	120	132	152	118	ACCS	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006520//cellular amino acid metabolic process;GO:0009058//biosynthetic process	--
ENSG00000110484	0	0	0	0	7.33	0	0	0	0	0	65	0	SCGB2A2	secretoglobin family 2A member 2 [Source:HGNC Symbol;Acc:HGNC:7050]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0030521//androgen receptor signaling pathway	--
ENSG00000110492	243.506	261.711	218.093	193.076	164.663	166.111	4305	4621	2805	2508	2444	2123	MDK	midkine [Source:HGNC Symbol;Acc:HGNC:6972]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0035374//chondroitin sulfate binding;GO:1904399//heparan sulfate binding	"GO:0001662//behavioral fear response;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002286//T cell activation involved in immune response;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007010//cytoskeleton organization;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007614//short-term memory;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009725//response to hormone;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010838//positive regulation of keratinocyte proliferation;GO:0010976//positive regulation of neuron projection development;GO:0010996//response to auditory stimulus;GO:0016477//cell migration;GO:0021542//dentate gyrus development;GO:0021681//cerebellar granular layer development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030279//negative regulation of ossification;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0030421//defecation;GO:0032330//regulation of chondrocyte differentiation;GO:0032735//positive regulation of interleukin-12 production;GO:0042246//tissue regeneration;GO:0043524//negative regulation of neuron apoptotic process;GO:0044849//estrous cycle;GO:0045582//positive regulation of T cell differentiation;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0045785//positive regulation of cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046850//regulation of bone remodeling;GO:0048477//oogenesis;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050729//positive regulation of inflammatory response;GO:0050795//regulation of behavior;GO:0050896//response to stimulus;GO:0051384//response to glucocorticoid;GO:0051781//positive regulation of cell division;GO:0061036//positive regulation of cartilage development;GO:0071673//positive regulation of smooth muscle cell chemotaxis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0106015//negative regulation of inflammatory response to wounding;GO:0106016//positive regulation of inflammatory response to wounding;GO:0106091//glial cell projection elongation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901215//negative regulation of neuron death;GO:1903039//positive regulation of leukocyte cell-cell adhesion;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:1905555//positive regulation of blood vessel branching;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1905653//positive regulation of artery morphogenesis;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000391//positive regulation of neutrophil extravasation;GO:2001224//positive regulation of neuron migration"	--
ENSG00000110497	18.03	16.553	16.878	16.307	17.724	17.027	1734	1650	1299	1064	1445	1197	AMBRA1	autophagy and beclin 1 regulator 1 [Source:HGNC Symbol;Acc:HGNC:25990]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04137//Mitophagy - animal	K17985;K17985;K17985;K17985;K17985;K17985;K17985	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005930//axoneme;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0051020//GTPase binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0000045//autophagosome assembly;GO:0000209//protein polyubiquitination;GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006914//autophagy;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0010508//positive regulation of autophagy;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0016567//protein ubiquitination;GO:0021915//neural tube development;GO:0030154//cell differentiation;GO:0031667//response to nutrient levels;GO:0035307//positive regulation of protein dephosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0098780//response to mitochondrial depolarisation;GO:1901526//positive regulation of mitophagy;GO:1904544//positive regulation of free ubiquitin chain polymerization;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000110514	11.576	11.635	13.167	11.611	11.309	13.789	1128	1121	939	918	929	940	MADD	MAP kinase activating death domain [Source:HGNC Symbol;Acc:HGNC:6766]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0030295//protein kinase activator activity	GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0032147//activation of protein kinase activity;GO:0032483//regulation of Rab protein signal transduction;GO:0042981//regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0050790//regulation of catalytic activity;GO:0051726//regulation of cell cycle;GO:0097194//execution phase of apoptosis;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000110536	27.419	26.749	29.846	26.791	26.831	29.015	1069.33	980.15	836.08	731.76	804.79	763.85	PTPMT1	protein tyrosine phosphatase mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:26965]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008962//phosphatidylglycerophosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016311//dephosphorylation;GO:0032049//cardiolipin biosynthetic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:2001242//regulation of intrinsic apoptotic signaling pathway	--
ENSG00000110583	5.65	5.829	4.908	6.343	4.488	6.102	403	384	262	319	287	312	NAA40	"N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0043998//H2A histone acetyltransferase activity;GO:1990189//peptide-serine-N-acetyltransferase activity	GO:0006474//N-terminal protein amino acid acetylation;GO:0006629//lipid metabolic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation	--
ENSG00000110619	14.799	16.732	12.762	12.786	12.008	20.595	781	856	498	505	535	764	CARS1	cysteinyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:1493]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01883	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004817//cysteine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006423//cysteinyl-tRNA aminoacylation	--
ENSG00000110628	7.999	7.46	8.123	8.141	8.987	9.27	256	240	192	193	243	214	SLC22A18	solute carrier family 22 member 18 [Source:HGNC Symbol;Acc:HGNC:10964]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015299//solute:proton antiporter activity;GO:0022857//transmembrane transporter activity;GO:0031625//ubiquitin protein ligase binding	GO:0006811//ion transport;GO:0015695//organic cation transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000110651	275.99	288.27	261.64	278.929	278.565	240.193	7423	7830	5324	5639	6281	4736	CD81	CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701]	Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune system;Infectious disease: parasitic	ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05144//Malaria	K06508;K06508;K06508	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome;GO:0097197//tetraspanin-enriched microdomain	GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0023026//MHC class II protein complex binding;GO:0042289//MHC class II protein binding;GO:1990459//transferrin receptor binding	"GO:0001771//immunological synapse formation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002863//positive regulation of inflammatory response to antigenic stimulus;GO:0008104//protein localization;GO:0008284//positive regulation of cell population proliferation;GO:0014905//myoblast fusion involved in skeletal muscle regeneration;GO:0030890//positive regulation of B cell proliferation;GO:0031623//receptor internalization;GO:0031647//regulation of protein stability;GO:0034238//macrophage fusion;GO:0035783//CD4-positive, alpha-beta T cell costimulation;GO:0043128//positive regulation of 1-phosphatidylinositol 4-kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation;GO:0061462//protein localization to lysosome;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0072659//protein localization to plasma membrane;GO:0072675//osteoclast fusion;GO:1903911//positive regulation of receptor clustering;GO:1904352//positive regulation of protein catabolic process in the vacuole;GO:1905521//regulation of macrophage migration;GO:1905676//positive regulation of adaptive immune memory response;GO:2000145//regulation of cell motility;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:2001190//positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell"	--
ENSG00000110660	1.306	1.51	1.515	1.779	1.627	1.436	75	84	60	56	80	61	SLC35F2	solute carrier family 35 member F2 [Source:HGNC Symbol;Acc:HGNC:23615]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0022857//transmembrane transporter activity	GO:0008150//biological_process;GO:0055085//transmembrane transport	--
ENSG00000110665	1.754	2.131	2.121	1.254	1.451	1.67	103	116	92	42	72	67	C11orf21	chromosome 11 open reading frame 21 [Source:HGNC Symbol;Acc:HGNC:13231]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000110675	0.016	0.026	0	0.033	0.061	0	1	1	0	1	3	0	ELMOD1	ELMO domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25334]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0043547//positive regulation of GTPase activity	--
ENSG00000110680	0	0	0	0	0	0	0	0	0	0	0	0	CALCA	calcitonin related polypeptide alpha [Source:HGNC Symbol;Acc:HGNC:1437]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction	K12332;K12332	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031716//calcitonin receptor binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	"GO:0001935//endothelial cell proliferation;GO:0001944//vasculature development;GO:0001976//nervous system process involved in regulation of systemic arterial blood pressure;GO:0001984//artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure;GO:0002031//G protein-coupled receptor internalization;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006954//inflammatory response;GO:0007159//leukocyte cell-cell adhesion;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007566//embryo implantation;GO:0007568//aging;GO:0007631//feeding behavior;GO:0008016//regulation of heart contraction;GO:0008217//regulation of blood pressure;GO:0009408//response to heat;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0030279//negative regulation of ossification;GO:0031623//receptor internalization;GO:0032147//activation of protein kinase activity;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032757//positive regulation of interleukin-8 production;GO:0042311//vasodilation;GO:0043542//endothelial cell migration;GO:0045651//positive regulation of macrophage differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045776//negative regulation of blood pressure;GO:0045779//negative regulation of bone resorption;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045986//negative regulation of smooth muscle contraction;GO:0048265//response to pain;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0097647//amylin receptor signaling pathway;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990408//calcitonin gene-related peptide receptor signaling pathway"	--
ENSG00000110693	17.073	15.98	15.187	13.56	13.96	17.61	3182	2952	2093	1878	2211	2387	SOX6	SRY-box transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:16421]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity"	"GO:0001502//cartilage condensation;GO:0002062//chondrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007517//muscle organ development;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0030154//cell differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0045165//cell fate commitment;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051216//cartilage development;GO:0061036//positive regulation of cartilage development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000726//negative regulation of cardiac muscle cell differentiation;GO:2000741//positive regulation of mesenchymal stem cell differentiation"	HMG
ENSG00000110696	65.486	62.309	60.006	59.169	55.121	67.102	2821	2677	1964.89	1983	2073	2130	C11orf58	chromosome 11 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:16990]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000110697	21.243	19.664	22.118	23.983	22.53	23.266	1647	1482	1230	1195	1309	1325	PITPNM1	phosphatidylinositol transfer protein membrane associated 1 [Source:HGNC Symbol;Acc:HGNC:9003]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0110165//cellular anatomical entity	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transfer activity;GO:0030971//receptor tyrosine kinase binding;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding;GO:0070300//phosphatidic acid binding	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007420//brain development;GO:0007602//phototransduction;GO:0015031//protein transport;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000110700	291.735	289.44	304.609	330.231	284.679	277.432	3188	3179	2459	2673	2628	2206	RPS13	ribosomal protein S13 [Source:HGNC Symbol;Acc:HGNC:10386]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02953;K02953	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding;GO:0070181//small ribosomal subunit rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0033119//negative regulation of RNA splicing	--
ENSG00000110711	26.522	29.362	29.544	36.675	34.801	31.773	680	756	559	693	753	592	AIP	aryl hydrocarbon receptor interacting protein [Source:HGNC Symbol;Acc:HGNC:358]	Human Diseases;Human Diseases	Cancer: overview;Endocrine and metabolic disease	ko05207//Chemical carcinogenesis - receptor activation;ko04934//Cushing syndrome	K17767;K17767	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034751//aryl hydrocarbon receptor complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0036004//GAF domain binding;GO:0051082//unfolded protein binding	"GO:0000413//protein peptidyl-prolyl isomerization;GO:0006355//regulation of transcription, DNA-templated;GO:0006626//protein targeting to mitochondrion;GO:0006805//xenobiotic metabolic process;GO:0010738//regulation of protein kinase A signaling;GO:0022417//protein maturation by protein folding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity"	--
ENSG00000110713	26.682	24.38	22.428	22.288	22.53	24.233	2259	2114	1721	1519	1819	1704	NUP98	nucleoporin 98 and 96 precursor [Source:HGNC Symbol;Acc:HGNC:8068]	Human Diseases;Human Diseases;Genetic Information Processing	Neurodegenerative disease;Infectious disease: viral;Translation	ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K14297;K14297;K14297	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0042405//nuclear inclusion body;GO:0044615//nuclear pore nuclear basket;GO:1990904//ribonucleoprotein complex	GO:0003713//transcription coactivator activity;GO:0003729//mRNA binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017056//structural constituent of nuclear pore;GO:0042277//peptide binding;GO:1990841//promoter-specific chromatin binding	"GO:0006508//proteolysis;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0015031//protein transport;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly"	--
ENSG00000110717	69.205	70.208	85.532	91.888	76.964	84.257	1050	1070	959	1036	985	924	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8 [Source:HGNC Symbol;Acc:HGNC:7715]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941;K03941	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070469//respirasome	"GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006979//response to oxidative stress;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000110719	9.947	10.545	9.652	11.01	12.512	10.557	538	569	376	444	558	403	TCIRG1	"T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 [Source:HGNC Symbol;Acc:HGNC:11647]"	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154	"GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0045335//phagocytic vesicle;GO:0101003//ficolin-1-rich granule membrane"	"GO:0005215//transporter activity;GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0000045//autophagosome assembly;GO:0001503//ossification;GO:0002158//osteoclast proliferation;GO:0006811//ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007035//vacuolar acidification;GO:0007039//protein catabolic process in the vacuole;GO:0007042//lysosomal lumen acidification;GO:0008284//positive regulation of cell population proliferation;GO:0010155//regulation of proton transport;GO:0010272//response to silver ion;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0016064//immunoglobulin mediated immune response;GO:0016236//macroautophagy;GO:0021554//optic nerve development;GO:0030010//establishment of cell polarity;GO:0030099//myeloid cell differentiation;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030316//osteoclast differentiation;GO:0031529//ruffle organization;GO:0033365//protein localization to organelle;GO:0035709//memory T cell activation;GO:0035711//T-helper 1 cell activation;GO:0042476//odontogenesis;GO:0043029//T cell homeostasis;GO:0044691//tooth eruption;GO:0045453//bone resorption;GO:0045667//regulation of osteoblast differentiation;GO:0045851//pH reduction;GO:0048872//homeostasis of number of cells;GO:0050796//regulation of insulin secretion;GO:0051452//intracellular pH reduction;GO:0051650//establishment of vesicle localization;GO:0060041//retina development in camera-type eye;GO:0061484//hematopoietic stem cell homeostasis;GO:0070166//enamel mineralization;GO:0071345//cellular response to cytokine stimulus;GO:0090383//phagosome acidification;GO:0097188//dentin mineralization;GO:1902600//proton transmembrane transport	--
ENSG00000110721	17.82	19.032	21.382	25.559	17.785	24.847	983	907	732	916	814	867	CHKA	choline kinase alpha [Source:HGNC Symbol;Acc:HGNC:1937]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism	K14156;K14156;K14156	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004103//choline kinase activity;GO:0004104//cholinesterase activity;GO:0004305//ethanolamine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0006869//lipid transport;GO:0008654//phospholipid biosynthetic process;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042149//cellular response to glucose starvation;GO:1905691//lipid droplet disassembly	--
ENSG00000110723	0.875	0.554	0.822	0.328	0.441	0.493	187	119	123	52	64	66	EXPH5	exophilin 5 [Source:HGNC Symbol;Acc:HGNC:30578]	-	-	-	-	GO:0005768//endosome	GO:0031267//small GTPase binding	GO:0003334//keratinocyte development;GO:0006886//intracellular protein transport;GO:0045921//positive regulation of exocytosis;GO:0050714//positive regulation of protein secretion;GO:0071985//multivesicular body sorting pathway	--
ENSG00000110756	7.144	7.452	6.495	6.48	6.767	6.24	673	715	426	430	532	439	HPS5	HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 [Source:HGNC Symbol;Acc:HGNC:17022]	-	-	-	-	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0031084//BLOC-2 complex	GO:0005515//protein binding	GO:0006996//organelle organization;GO:0007596//blood coagulation;GO:0043473//pigmentation;GO:0046907//intracellular transport;GO:0048066//developmental pigmentation;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000110768	19.452	15.974	15.975	13.332	12.285	14.889	1087	908	667	530	602	630	GTF2H1	general transcription factor IIH subunit 1 [Source:HGNC Symbol;Acc:HGNC:4655]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Transcription;Replication and repair	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K03141;K03141;K03141	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005675//transcription factor TFIIH holo complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046966//thyroid hormone receptor binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006360//transcription by RNA polymerase I;GO:0006366//transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0009755//hormone-mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain"	--
ENSG00000110777	0	0	0	0	0	0	0	0	0	0	0	0	POU2AF1	POU class 2 homeobox associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211]	-	-	-	-	GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0002314//germinal center B cell differentiation;GO:0006959//humoral immune response;GO:0032755//positive regulation of interleukin-6 production;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0098586//cellular response to virus	--
ENSG00000110786	0	0	0.028	0.028	0	0	0	0	1	1	0	0	PTPN5	protein tyrosine phosphatase non-receptor type 5 [Source:HGNC Symbol;Acc:HGNC:9657]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K18018	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001784//phosphotyrosine residue binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000110799	0.022	0.043	0.022	0.037	0.09	0.06	4	8	3	5	14	8	VWF	von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Infectious disease: viral;Immune system;Cellular community - eukaryotes;Immune system;Immune system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko04510//Focal adhesion;ko04611//Platelet activation;ko04610//Complement and coagulation cascades;ko04512//ECM-receptor interaction	K03900;K03900;K03900;K03900;K03900;K03900;K03900;K03900	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031012//extracellular matrix;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0033093//Weibel-Palade body;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0019865//immunoglobulin binding;GO:0042802//identical protein binding;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding	GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009611//response to wounding;GO:0030168//platelet activation;GO:0031589//cell-substrate adhesion;GO:1902533//positive regulation of intracellular signal transduction	--
ENSG00000110801	20.172	25.207	30.702	26.948	22.512	27.049	545	529	392	403	405	379	PSMD9	"proteasome 26S subunit, non-ATPase 9 [Source:HGNC Symbol;Acc:HGNC:9567]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K06693;K06693;K06693;K06693;K06693;K06693;K06693;K06693	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008540//proteasome regulatory particle, base subcomplex"	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043425//bHLH transcription factor binding	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032024//positive regulation of insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046676//negative regulation of insulin secretion;GO:0070682//proteasome regulatory particle assembly"	--
ENSG00000110811	33.735	37.373	35.306	33.496	34.877	29.214	1841	2050	1423	1354	1608	1160	P3H3	prolyl 3-hydroxylase 3 [Source:HGNC Symbol;Acc:HGNC:19318]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:1902494//catalytic complex	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0008285//negative regulation of cell population proliferation;GO:0017185//peptidyl-lysine hydroxylation;GO:0019511//peptidyl-proline hydroxylation;GO:0032963//collagen metabolic process;GO:0032964//collagen biosynthetic process	--
ENSG00000110841	10.76	9.057	9.816	8.991	8.516	7.574	788	627	466	445	508	451	PPFIBP1	PPFIA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9249]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0048786//presynaptic active zone	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007155//cell adhesion;GO:0007528//neuromuscular junction development;GO:0050808//synapse organization	--
ENSG00000110844	4.528	5.563	4.696	4.669	5.007	4.258	298.05	367.98	228.19	227.22	278.11	204.16	PRPF40B	pre-mRNA processing factor 40 homolog B [Source:HGNC Symbol;Acc:HGNC:25031]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12821	GO:0005634//nucleus;GO:0005685//U1 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000110848	0	0	0	0	0.056	0	0	0	0	0	1	0	CD69	CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding	GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000110851	9.399	8.476	8.714	7.583	8.951	8.033	784	724	544	478	656	507	PRDM4	PR/SET domain 4 [Source:HGNC Symbol;Acc:HGNC:9348]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12463	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0035097//histone methyltransferase complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1990226//histone methyltransferase binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006366//transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0032259//methylation;GO:0043985//histone H4-R3 methylation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000110852	0.031	0.031	0	0	0.091	0	1	1	0	0	2	0	CLEC2B	C-type lectin domain family 2 member B [Source:HGNC Symbol;Acc:HGNC:2053]	Human Diseases	Infectious disease: viral	ko05167//Kaposi sarcoma-associated herpesvirus infection	K10071	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding	-	--
ENSG00000110871	17.719	17.961	19.166	19.188	18.416	15.618	530	529	416	428	450	345	COQ5	"coenzyme Q5, methyltransferase [Source:HGNC Symbol;Acc:HGNC:28722]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K06127;K06127	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0032991//protein-containing complex;GO:0110142//ubiquinone biosynthesis complex	"GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0043333//2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity;GO:0043430//2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"	GO:0006744//ubiquinone biosynthetic process;GO:0032259//methylation	--
ENSG00000110876	0.019	0.059	0.482	0.323	0.435	0.205	1	2	12	8	14	5	SELPLG	selectin P ligand [Source:HGNC Symbol;Acc:HGNC:10722]	Organismal Systems;Human Diseases;Environmental Information Processing	Immune system;Infectious disease: bacterial;Signaling molecules and interaction	ko04613//Neutrophil extracellular trap formation;ko05150//Staphylococcus aureus infection;ko04514//Cell adhesion molecules	K06544;K06544;K06544	GO:0001931//uropod;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044853//plasma membrane raft	GO:0001618//virus receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0030097//hemopoiesis;GO:0046718//viral entry into host cell;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0050902//leukocyte adhesive activation;GO:0071354//cellular response to interleukin-6	--
ENSG00000110880	33.087	37.463	31.681	27.597	28.921	24.494	2203	2248	1548	1154	1503	1115	CORO1C	coronin 1C [Source:HGNC Symbol;Acc:HGNC:2254]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0016600//flotillin complex;GO:0030017//sarcomere;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031982//vesicle;GO:0032587//ruffle membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding	GO:0001755//neural crest cell migration;GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0006909//phagocytosis;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0010632//regulation of epithelial cell migration;GO:0010633//negative regulation of epithelial cell migration;GO:0010762//regulation of fibroblast migration;GO:0016197//endosomal transport;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045184//establishment of protein localization;GO:0051893//regulation of focal adhesion assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0090148//membrane fission;GO:0090630//activation of GTPase activity;GO:0097750//endosome membrane tubulation;GO:0140285//endosome fission;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900027//regulation of ruffle assembly;GO:2000394//positive regulation of lamellipodium morphogenesis	--
ENSG00000110881	1.325	1.024	1.272	1.491	1.459	1.535	97	83	72	89	100	90	ASIC1	acid sensing ion channel subunit 1 [Source:HGNC Symbol;Acc:HGNC:100]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04829	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0022839//ion gated channel activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0044736//acid-sensing ion channel activity	GO:0001662//behavioral fear response;GO:0001975//response to amphetamine;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0007613//memory;GO:0008306//associative learning;GO:0009268//response to pH;GO:0010447//response to acidic pH;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0046929//negative regulation of neurotransmitter secretion;GO:0050915//sensory perception of sour taste;GO:0070207//protein homotrimerization;GO:0070588//calcium ion transmembrane transport;GO:0071467//cellular response to pH;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000110887	0.028	0	0	0	0	0	1	0	0	0	0	0	DAO	D-amino acid oxidase [Source:HGNC Symbol;Acc:HGNC:2671]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko00330//Arginine and proline metabolism;ko00260//Glycine, serine and threonine metabolism;ko00470//D-Amino acid metabolism"	K00273;K00273;K00273;K00273;K00273	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0003884//D-amino-acid oxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0071949//FAD binding	GO:0006520//cellular amino acid metabolic process;GO:0006562//proline catabolic process;GO:0019478//D-amino acid catabolic process;GO:0036088//D-serine catabolic process;GO:0042416//dopamine biosynthetic process;GO:0046416//D-amino acid metabolic process;GO:0055130//D-alanine catabolic process;GO:0070178//D-serine metabolic process	--
ENSG00000110888	6.084	6.102	5.282	4.245	5.171	4.403	481	440	310	253	305	244	CAPRIN2	caprin family member 2 [Source:HGNC Symbol;Acc:HGNC:21259]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043235//receptor complex	GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0032092//positive regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0040008//regulation of growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050775//positive regulation of dendrite morphogenesis;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000110900	12.334	12.865	13.542	13.01	13.39	12.401	1305	1389	1093	1038	1193	965	TSPAN11	tetraspanin 11 [Source:HGNC Symbol;Acc:HGNC:30795]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0016477//cell migration	--
ENSG00000110906	21.985	20.675	23.858	16.648	22.072	18.431	1600	1618	1243	985	1277	1062	KCTD10	potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051260//protein homooligomerization	--
ENSG00000110911	14.933	14.38	13.358	15.301	17.964	20.158	1120	1015	749	829	1113	1065	SLC11A2	solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]	Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Digestive system;Cell growth and death	ko05010//Alzheimer disease;ko05012//Parkinson disease;ko04142//Lysosome;ko04978//Mineral absorption;ko04216//Ferroptosis	K21398;K21398;K21398;K21398;K21398	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0031902//late endosome membrane;GO:0045177//apical part of cell;GO:0045178//basal part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070826//paraferritin complex;GO:1903561//extracellular vesicle	GO:0005375//copper ion transmembrane transporter activity;GO:0005381//iron ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0015086//cadmium ion transmembrane transporter activity;GO:0015087//cobalt ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015094//lead ion transmembrane transporter activity;GO:0015099//nickel cation transmembrane transporter activity;GO:0015100//vanadium ion transmembrane transporter activity;GO:0015295//solute:proton symporter activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0046870//cadmium ion binding;GO:0046873//metal ion transmembrane transporter activity;GO:0046915//transition metal ion transmembrane transporter activity;GO:1905394//retromer complex binding	GO:0001666//response to hypoxia;GO:0003032//detection of oxygen;GO:0006778//porphyrin-containing compound metabolic process;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006783//heme biosynthetic process;GO:0006811//ion transport;GO:0006824//cobalt ion transport;GO:0006825//copper ion transport;GO:0006826//iron ion transport;GO:0006828//manganese ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007611//learning or memory;GO:0010039//response to iron ion;GO:0015675//nickel cation transport;GO:0015676//vanadium ion transport;GO:0015692//lead ion transport;GO:0030001//metal ion transport;GO:0033212//iron import into cell;GO:0034599//cellular response to oxidative stress;GO:0034755//iron ion transmembrane transport;GO:0035434//copper ion transmembrane transport;GO:0035444//nickel cation transmembrane transport;GO:0048813//dendrite morphogenesis;GO:0048821//erythrocyte development;GO:0055072//iron ion homeostasis;GO:0060586//multicellular organismal iron ion homeostasis;GO:0070574//cadmium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000110917	57.712	57.817	58.375	57.219	61.037	58.413	7114	7237	5329	5542	6342	5535	MLEC	malectin [Source:HGNC Symbol;Acc:HGNC:28973]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030246//carbohydrate binding	GO:0005975//carbohydrate metabolic process;GO:0006487//protein N-linked glycosylation	--
ENSG00000110921	8.886	9.776	11.905	15.241	10.698	10.174	314	330.91	264	362	297	253	MVK	mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00900//Terpenoid backbone biosynthesis	K00869;K00869;K00869	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004496//mevalonate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0016310//phosphorylation;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0050728//negative regulation of inflammatory response"	--
ENSG00000110925	12.769	11.411	12.014	10.306	11.935	14.985	1090	962	728	608	804	861	CSRNP2	cysteine and serine rich nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16006]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0043565//sequence-specific DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II	CSRNP_N
ENSG00000110931	6.505	5.105	5.73	5.354	4.836	5.453	514	519	378	351	416	323	CAMKK2	calcium/calmodulin dependent protein kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:1470]	Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Substance dependence;Endocrine system;Transport and catabolism;Endocrine and metabolic disease;Signal transduction;Aging;Endocrine system	ko05034//Alcoholism;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway	K07359;K07359;K07359;K07359;K07359;K07359;K07359	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019722//calcium-mediated signaling;GO:0034614//cellular response to reactive oxygen species;GO:0045859//regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0061762//CAMKK-AMPK signaling cascade;GO:1903599//positive regulation of autophagy of mitochondrion"	--
ENSG00000110934	0	0	0	0	0.057	0	0	0	0	0	2	0	BIN2	bridging integrator 2 [Source:HGNC Symbol;Acc:HGNC:1053]	-	-	-	-	GO:0001891//phagocytic cup;GO:0002102//podosome;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030054//cell junction;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0005543//phospholipid binding	"GO:0006911//phagocytosis, engulfment;GO:0060326//cell chemotaxis;GO:0071800//podosome assembly;GO:0097320//plasma membrane tubulation"	--
ENSG00000110944	0.046	0	0.189	0.188	0.055	0.064	1	0	3	3	1	1	IL23A	interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Signaling molecules and interaction;Infectious disease: bacterial;Signal transduction;Immune disease;Immune system;Immune system;Infectious disease: bacterial;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko04630//JAK-STAT signaling pathway;ko05323//Rheumatoid arthritis;ko04659//Th17 cell differentiation;ko04625//C-type lectin receptor signaling pathway;ko05133//Pertussis;ko05321//Inflammatory bowel disease	K05426;K05426;K05426;K05426;K05426;K05426;K05426;K05426;K05426	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0070743//interleukin-23 complex	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0045519//interleukin-23 receptor binding	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0032693//negative regulation of interleukin-10 production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0032819//positive regulation of natural killer cell proliferation;GO:0034105//positive regulation of tissue remodeling;GO:0042098//T cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043382//positive regulation of memory T cell differentiation;GO:0045087//innate immune response;GO:0045672//positive regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048771//tissue remodeling;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0051135//positive regulation of NK T cell activation;GO:0051142//positive regulation of NK T cell proliferation;GO:0051607//defense response to virus;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000330//positive regulation of T-helper 17 cell lineage commitment	--
ENSG00000110955	364.563	376.44	408.497	440.593	402.742	433.387	13255	13789	10923	11880	12369	11505	ATP5F1B	ATP synthase F1 subunit beta [Source:HGNC Symbol;Acc:HGNC:830]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02133;K02133;K02133;K02133;K02133;K02133;K02133;K02133;K02133;K02133;K02133	"GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0042645//mitochondrial nucleoid;GO:0045259//proton-transporting ATP synthase complex;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0070062//extracellular exosome"	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042288//MHC class I protein binding;GO:0043532//angiostatin binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0001525//angiogenesis;GO:0001649//osteoblast differentiation;GO:0006091//generation of precursor metabolites and energy;GO:0006629//lipid metabolic process;GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0006996//organelle organization;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0046034//ATP metabolic process;GO:0051453//regulation of intracellular pH;GO:0098761//cellular response to interleukin-7;GO:1902600//proton transmembrane transport	--
ENSG00000110958	99.948	100.379	91.671	84.433	91.942	91.677	3737	3718	2558	2352	2854	2461	PTGES3	prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko00590//Arachidonic acid metabolism	K15730;K15730;K15730	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0101031//chaperone complex"	GO:0003720//telomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0050220//prostaglandin-E synthase activity;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding;GO:0070182//DNA polymerase binding	GO:0000723//telomere maintenance;GO:0001516//prostaglandin biosynthetic process;GO:0005978//glycogen biosynthetic process;GO:0006457//protein folding;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0007004//telomere maintenance via telomerase;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0019371//cyclooxygenase pathway;GO:0042327//positive regulation of phosphorylation;GO:0042921//glucocorticoid receptor signaling pathway;GO:0043588//skin development;GO:0050821//protein stabilization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051131//chaperone-mediated protein complex assembly;GO:0051973//positive regulation of telomerase activity;GO:0060430//lung saccule development;GO:1905323//telomerase holoenzyme complex assembly	--
ENSG00000110975	1.427	0.935	1.174	1.013	1.049	1.081	132	87	75	49	82	72	SYT10	synaptotagmin 10 [Source:HGNC Symbol;Acc:HGNC:19266]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0070382//exocytic vesicle	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0071277//cellular response to calcium ion	--
ENSG00000110987	4.428	5.17	4.066	4.366	4.933	5.695	351	414	242	265	328	331	BCL7A	BAF chromatin remodeling complex subunit BCL7A [Source:HGNC Symbol;Acc:HGNC:1004]	-	-	-	-	GO:0000785//chromatin;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000111011	12.67	15.116	12.672	7.412	10.624	10.69	545	551	374	246	330	311	RSRC2	arginine and serine rich coiled-coil 2 [Source:HGNC Symbol;Acc:HGNC:30559]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000111012	0	0.04	0.08	0.055	0.12	0	0	2	2	2	5	0	CYP27B1	cytochrome P450 family 27 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2606]	Metabolism;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Infectious disease: bacterial;Endocrine system;Lipid metabolism	"ko01100//Metabolic pathways;ko05152//Tuberculosis;ko04928//Parathyroid hormone synthesis, secretion and action;ko00100//Steroid biosynthesis"	K07438;K07438;K07438;K07438	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane	"GO:0004497//monooxygenase activity;GO:0004498//calcidiol 1-monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0062185//secalciferol 1-monooxygenase activity"	GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006816//calcium ion transport;GO:0008285//negative regulation of cell population proliferation;GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0030282//bone mineralization;GO:0030308//negative regulation of cell growth;GO:0030500//regulation of bone mineralization;GO:0032496//response to lipopolysaccharide;GO:0033280//response to vitamin D;GO:0034341//response to interferon-gamma;GO:0036378//calcitriol biosynthetic process from calciol;GO:0042359//vitamin D metabolic process;GO:0042368//vitamin D biosynthetic process;GO:0042369//vitamin D catabolic process;GO:0043627//response to estrogen;GO:0045618//positive regulation of keratinocyte differentiation;GO:0046697//decidualization;GO:0055074//calcium ion homeostasis;GO:0070314//G1 to G0 transition;GO:0070564//positive regulation of vitamin D receptor signaling pathway	--
ENSG00000111046	0	0	0	0	0	0	0	0	0	0	0	0	MYF6	myogenic factor 6 [Source:HGNC Symbol;Acc:HGNC:7566]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0042693//muscle cell fate commitment;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0060415//muscle tissue morphogenesis"	bHLH
ENSG00000111049	0	0	0	0	0	0	0	0	0	0	0	0	MYF5	myogenic factor 5 [Source:HGNC Symbol;Acc:HGNC:7565]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18484	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding"	"GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0001756//somitogenesis;GO:0001952//regulation of cell-matrix adhesion;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0035914//skeletal muscle cell differentiation;GO:0042693//muscle cell fate commitment;GO:0043010//camera-type eye development;GO:0045663//positive regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048644//muscle organ morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0060415//muscle tissue morphogenesis"	bHLH
ENSG00000111052	16.407	10.404	12.256	13.277	12.226	16.002	2004	1307	1086	993	1213	1328	LIN7A	"lin-7 homolog A, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17787]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0097016//L27 domain binding	GO:0006887//exocytosis;GO:0007269//neurotransmitter secretion;GO:0015031//protein transport;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0048489//synaptic vesicle transport;GO:0048839//inner ear development;GO:0065003//protein-containing complex assembly;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000111057	157.611	162.13	114.299	139.728	136.221	117.091	4622	4776.99	2475	3034	3374	2498	KRT18	keratin 18 [Source:HGNC Symbol;Acc:HGNC:6430]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005912//adherens junction;GO:0034451//centriolar satellite;GO:0045095//keratin filament;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0097110//scaffold protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0007049//cell cycle;GO:0009653//anatomical structure morphogenesis;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043000//Golgi to plasma membrane CFTR protein transport;GO:0043066//negative regulation of apoptotic process;GO:0045104//intermediate filament cytoskeleton organization;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097284//hepatocyte apoptotic process;GO:0098609//cell-cell adhesion	--
ENSG00000111058	3.408	4.006	3.556	3.121	3.436	3.376	293	332	246	190	249	197	ACSS3	acyl-CoA synthetase short chain family member 3 [Source:HGNC Symbol;Acc:HGNC:24723]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00640//Propanoate metabolism	K01908;K01908	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003987//acetate-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0016878//acid-thiol ligase activity;GO:0047760//butyrate-CoA ligase activity;GO:0050218//propionate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0046951//ketone body biosynthetic process	--
ENSG00000111077	4.71	4.775	3.876	3.254	3.547	5.851	304	341	217	211	278	244	TNS2	tensin 2 [Source:HGNC Symbol;Acc:HGNC:19737]	-	-	-	-	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0098794//postsynapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0008285//negative regulation of cell population proliferation;GO:0014850//response to muscle activity;GO:0019725//cellular homeostasis;GO:0032963//collagen metabolic process;GO:0035264//multicellular organism growth;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048871//multicellular organismal homeostasis	--
ENSG00000111087	0.114	0.09	0.041	0.163	0.036	0.117	8	6	2	8	2	7	GLI1	GLI family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4317]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04024//cAMP signaling pathway;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K16797;K16797;K16797;K16797	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0005930//axoneme;GO:0097542//ciliary tip;GO:0097546//ciliary base;GO:1990788//GLI-SUFU complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0001649//osteoblast differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0007418//ventral midline development;GO:0008284//positive regulation of cell population proliferation;GO:0008589//regulation of smoothened signaling pathway;GO:0009611//response to wounding;GO:0009913//epidermal cell differentiation;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0021696//cerebellar cortex morphogenesis;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0030850//prostate gland development;GO:0045667//regulation of osteoblast differentiation;GO:0045740//positive regulation of DNA replication;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048546//digestive tract morphogenesis;GO:0060032//notochord regression;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097421//liver regeneration;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1990787//negative regulation of hh target transcription factor activity;GO:2000345//regulation of hepatocyte proliferation"	zf-C2H2
ENSG00000111110	12.348	13.407	12.238	12.606	14.845	14.876	1653	1804	1210	1250	1679	1449	PPM1H	"protein phosphatase, Mg2+/Mn2+ dependent 1H [Source:HGNC Symbol;Acc:HGNC:18583]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042802//identical protein binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000111142	25.748	23.183	21.4	19.837	19.584	22.084	1110	955	658	619	715	684	METAP2	methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003723//RNA binding;GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0016485//protein processing;GO:0018206//peptidyl-methionine modification;GO:0031365//N-terminal protein amino acid modification;GO:0044238//primary metabolic process;GO:0070084//protein initiator methionine removal;GO:0071704//organic substance metabolic process	--
ENSG00000111144	54.628	53.379	57.597	58.929	53.479	58.365	2371	2339	1850	1902	1984	1852	LTA4H	leukotriene A4 hydrolase [Source:HGNC Symbol;Acc:HGNC:6710]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K01254;K01254	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0004177//aminopeptidase activity;GO:0004301//epoxide hydrolase activity;GO:0004463//leukotriene-A4 hydrolase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0045148//tripeptide aminopeptidase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process;GO:0010043//response to zinc ion;GO:0019370//leukotriene biosynthetic process;GO:0043171//peptide catabolic process;GO:0043434//response to peptide hormone;GO:0044267//cellular protein metabolic process;GO:0060509//type I pneumocyte differentiation	--
ENSG00000111145	8.965	6.965	6.118	5.475	5.89	5.552	646	610	378	347	411	352	ELK3	ETS transcription factor ELK3 [Source:HGNC Symbol;Acc:HGNC:3325]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0032422//purine-rich negative regulatory element binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0042060//wound healing;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000111181	3.213	3.185	3.416	2.529	2.274	2.619	213	201	167	123	127	124	SLC6A12	solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle	K05045;K05045	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0098793//presynapse	GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0015718//monocarboxylic acid transport;GO:0035725//sodium ion transmembrane transport;GO:0051936//gamma-aminobutyric acid reuptake;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport	--
ENSG00000111186	1.214	1.612	1.432	1.395	1.169	1.135	52	67	42	37	35	31	WNT5B	Wnt family member 5B [Source:HGNC Symbol;Acc:HGNC:16265]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Development and regeneration;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity	GO:0002062//chondrocyte differentiation;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0042060//wound healing;GO:0042692//muscle cell differentiation;GO:0045165//cell fate commitment;GO:0045444//fat cell differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0070307//lens fiber cell development;GO:0071300//cellular response to retinoic acid;GO:1904105//positive regulation of convergent extension involved in gastrulation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway	--
ENSG00000111196	4.391	5.086	3.774	3.882	3.434	3.341	99	102	73	66	80	60	MAGOHB	"mago homolog B, exon junction complex subunit [Source:HGNC Symbol;Acc:HGNC:25504]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12877;K12877;K12877	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0043025//neuronal cell body;GO:0071005//U2-type precatalytic spliceosome;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:1990501//exon-exon junction subcomplex mago-y14	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:2000622//regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000111199	22.647	23.541	21.645	16.325	17.571	16.94	1459	1491	1007	760	960	792	TRPV4	transient receptor potential cation channel subfamily V member 4 [Source:HGNC Symbol;Acc:HGNC:18083]	Cellular Processes;Human Diseases;Organismal Systems	Cell growth and death;Cardiovascular disease;Sensory system	ko04218//Cellular senescence;ko05418//Fluid shear stress and atherosclerosis;ko04750//Inflammatory mediator regulation of TRP channels	K04973;K04973;K04973	GO:0005783//endoplasmic reticulum;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030426//growth cone;GO:0030864//cortical actin cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0005034//osmosensor activity;GO:0005080//protein kinase C binding;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0015275//stretch-activated, cation-selective, calcium channel activity;GO:0019901//protein kinase binding;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding;GO:0051015//actin filament binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002024//diet induced thermogenesis;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006884//cell volume homeostasis;GO:0006970//response to osmotic stress;GO:0006971//hypotonic response;GO:0007015//actin filament organization;GO:0007043//cell-cell junction assembly;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007231//osmosensory signaling pathway;GO:0009612//response to mechanical stimulus;GO:0010628//positive regulation of gene expression;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010977//negative regulation of neuron projection development;GO:0030103//vasopressin secretion;GO:0031117//positive regulation of microtubule depolymerization;GO:0031532//actin cytoskeleton reorganization;GO:0032755//positive regulation of interleukin-6 production;GO:0032868//response to insulin;GO:0034220//ion transmembrane transport;GO:0034605//cellular response to heat;GO:0042538//hyperosmotic salinity response;GO:0042593//glucose homeostasis;GO:0043117//positive regulation of vascular permeability;GO:0043622//cortical microtubule organization;GO:0045989//positive regulation of striated muscle contraction;GO:0046330//positive regulation of JNK cascade;GO:0046785//microtubule polymerization;GO:0047484//regulation of response to osmotic stress;GO:0050729//positive regulation of inflammatory response;GO:0050891//multicellular organismal water homeostasis;GO:0055085//transmembrane transport;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0071470//cellular response to osmotic stress;GO:0071476//cellular hypotonic response;GO:0071477//cellular hypotonic salinity response;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0071642//positive regulation of macrophage inflammatory protein 1 alpha production;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0097009//energy homeostasis;GO:0097497//blood vessel endothelial cell delamination;GO:0098703//calcium ion import across plasma membrane;GO:1902656//calcium ion import into cytosol;GO:1903444//negative regulation of brown fat cell differentiation;GO:1903715//regulation of aerobic respiration;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production	--
ENSG00000111203	8.707	8.692	9.69	9.009	9.59	9.326	403.32	391.21	249.31	313	379.22	326	ITFG2	integrin alpha FG-GAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:30879]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0140007//KICSTOR complex	GO:0005515//protein binding	GO:0002314//germinal center B cell differentiation;GO:0007229//integrin-mediated signaling pathway;GO:0032006//regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000111206	1.328	0.956	1.365	1.704	1.173	1.952	61.68	70.79	54.69	92	71.78	66	FOXM1	forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K09406	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding"	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0042127//regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046578//regulation of Ras protein signal transduction;GO:0051726//regulation of cell cycle;GO:0090344//negative regulation of cell aging;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000781//positive regulation of double-strand break repair"	Fork_head
ENSG00000111215	0	0	0	0.259	0	0.069	0	0	0	2.24	0	0.59	PRR4	proline rich 4 [Source:HGNC Symbol;Acc:HGNC:18020]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13910	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0001895//retina homeostasis;GO:0007601//visual perception	--
ENSG00000111218	0	0	0	0	0	0	0	0	0	0	0	0	PRMT8	protein arginine methyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:5188]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0098753//anchored component of the cytoplasmic side of the plasma membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:1904047//S-adenosyl-L-methionine binding	"GO:0006479//protein methylation;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0032259//methylation;GO:0034969//histone arginine methylation;GO:0043393//regulation of protein binding;GO:0051260//protein homooligomerization"	--
ENSG00000111224	4.252	3.786	3.863	4.173	4.713	3.931	286	250	194	178	197	166	PARP11	poly(ADP-ribose) polymerase family member 11 [Source:HGNC Symbol;Acc:HGNC:1186]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0006998//nuclear envelope organization;GO:0007283//spermatogenesis;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0051028//mRNA transport;GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000111229	102.688	100.721	98.338	95.284	84.024	87.554	1864	1823	1235	1262	1247	1250	ARPC3	actin related protein 2/3 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:706]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05756;K05756;K05756;K05756;K05756;K05756;K05756;K05756;K05756	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0035861//site of double-strand break;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0070358//actin polymerization-dependent cell motility	--
ENSG00000111231	6.627	7.012	6.362	7.357	6.133	6.669	196	213	142	120	152	147	GPN3	GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186]	-	-	-	-	GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	-	--
ENSG00000111237	30.332	25.492	25.923	29.505	25.293	26.428	625	557	404	469	449	407	VPS29	VPS29 retromer complex component [Source:HGNC Symbol;Acc:HGNC:14340]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18467	"GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030904//retromer complex;GO:0030906//retromer, cargo-selective complex;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity"	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000111241	0	0	0	0	0	0	0	0	0	0	0	0	FGF6	fibroblast growth factor 6 [Source:HGNC Symbol;Acc:HGNC:3684]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001502//cartilage condensation;GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0045445//myoblast differentiation;GO:0051781//positive regulation of cell division	--
ENSG00000111245	0	0	0	0	0	0	0	0	0	0	0	0	MYL2	myosin light chain 2 [Source:HGNC Symbol;Acc:HGNC:7583]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Cellular community - eukaryotes;Cardiovascular disease;Circulatory system;Signal transduction;Immune system;Cardiovascular disease;Circulatory system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04530//Tight junction;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04670//Leukocyte transendothelial migration;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K10351;K10351;K10351;K10351;K10351;K10351;K10351;K10351;K10351;K10351;K10351	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0031672//A band;GO:0097512//cardiac myofibril	GO:0003785//actin monomer binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0032036//myosin heavy chain binding;GO:0046872//metal ion binding	GO:0002026//regulation of the force of heart contraction;GO:0006942//regulation of striated muscle contraction;GO:0007507//heart development;GO:0030308//negative regulation of cell growth;GO:0042694//muscle cell fate specification;GO:0055003//cardiac myofibril assembly;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060047//heart contraction;GO:0060048//cardiac muscle contraction;GO:0098735//positive regulation of the force of heart contraction	--
ENSG00000111247	1.692	0.925	1.351	0.678	0.324	0.572	44	33	27	22	12	13	RAD51AP1	RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0032991//protein-containing complex"	GO:0000217//DNA secondary structure binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0062037//D-loop DNA binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010845//positive regulation of reciprocal meiotic recombination;GO:0036297//interstrand cross-link repair;GO:0051321//meiotic cell cycle;GO:0071479//cellular response to ionizing radiation;GO:1905168//positive regulation of double-strand break repair via homologous recombination	--
ENSG00000111249	0.022	0.007	0	0	0	0	3	1	0	0	0	0	CUX2	cut like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:19347]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0070062//extracellular exosome	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007614//short-term memory;GO:0010628//positive regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050890//cognition;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071310//cellular response to organic substance;GO:2000463//positive regulation of excitatory postsynaptic potential"	CUT
ENSG00000111252	3.196	2.791	2.488	1.941	2.122	2.391	360	316	207	162	202	196	SH2B3	SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12459	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005173//stem cell factor receptor binding;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0035591//signaling adaptor activity;GO:1990782//protein tyrosine kinase binding	GO:0001780//neutrophil homeostasis;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0035162//embryonic hemopoiesis;GO:0035556//intracellular signal transduction;GO:0035702//monocyte homeostasis;GO:0035855//megakaryocyte development;GO:0036016//cellular response to interleukin-3;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0043407//negative regulation of MAP kinase activity;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0048821//erythrocyte development;GO:0051898//negative regulation of protein kinase B signaling;GO:0060761//negative regulation of response to cytokine stimulus;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0090331//negative regulation of platelet aggregation;GO:1900235//negative regulation of Kit signaling pathway;GO:1990869//cellular response to chemokine	--
ENSG00000111254	0.472	0.912	1.008	0.471	0.527	0.998	31	53	36	24	27	27	AKAP3	A-kinase anchoring protein 3 [Source:HGNC Symbol;Acc:HGNC:373]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0051018//protein kinase A binding	GO:0001835//blastocyst hatching;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007338//single fertilization;GO:0007340//acrosome reaction;GO:0008104//protein localization	--
ENSG00000111261	22.937	23.061	22.166	17.088	19.193	18.759	1096	1083	809	634	824	681	MANSC1	MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000111262	0	0.012	0	0	0.024	0.008	0	2	0	0	3	1	KCNA1	potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0033270//paranode region of axon;GO:0034705//potassium channel complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0044224//juxtaparanode region of axon;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015079//potassium ion transmembrane transporter activity;GO:0097718//disordered domain specific binding;GO:0099508//voltage-gated ion channel activity involved in regulation of presynaptic membrane potential;GO:1905030//voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0001964//startle response;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006937//regulation of muscle contraction;GO:0007268//chemical synaptic transmission;GO:0007405//neuroblast proliferation;GO:0007420//brain development;GO:0010644//cell communication by electrical coupling;GO:0010960//magnesium ion homeostasis;GO:0019228//neuronal action potential;GO:0021766//hippocampus development;GO:0023041//neuronal signal transduction;GO:0034613//cellular protein localization;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050905//neuromuscular process;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0050976//detection of mechanical stimulus involved in sensory perception of touch;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0060078//regulation of postsynaptic membrane potential;GO:0071286//cellular response to magnesium ion;GO:0071805//potassium ion transmembrane transport;GO:0099505//regulation of presynaptic membrane potential;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000111266	23.095	24.091	27.15	24.09	23.804	27.64	2637	2498	2161	2009	2242	2039	DUSP16	dual specificity phosphatase 16 [Source:HGNC Symbol;Acc:HGNC:17909]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0008432//JUN kinase binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0051019//mitogen-activated protein kinase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0043508//negative regulation of JUN kinase activity;GO:0045204//MAPK export from nucleus	--
ENSG00000111269	48.109	42.939	45.746	43.54	39.945	49.177	3762	3375	2642	2522	2639	2798	CREBL2	cAMP responsive element binding protein like 2 [Source:HGNC Symbol;Acc:HGNC:2350]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045600//positive regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046326//positive regulation of glucose import;GO:0046889//positive regulation of lipid biosynthetic process;GO:0050821//protein stabilization"	Others
ENSG00000111271	12.723	12.555	14.218	16.093	17.232	14.156	914	1040	840	793	1039	786	ACAD10	acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003995//acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding"	GO:0006635//fatty acid beta-oxidation	--
ENSG00000111275	27.905	26.649	26.426	26.087	31.057	28.381	1440.69	1425.61	1016.23	1033.38	1325.29	1091.11	ALDH2	aldehyde dehydrogenase 2 family member [Source:HGNC Symbol;Acc:HGNC:404]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism;ko00770//Pantothenate and CoA biosynthesis"	K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome	"GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0008957//phenylacetaldehyde dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0018547//nitroglycerin reductase activity;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity;GO:0051287//NAD binding;GO:0052689//carboxylic ester hydrolase activity"	GO:0005975//carbohydrate metabolic process;GO:0006066//alcohol metabolic process;GO:0006068//ethanol catabolic process;GO:0022900//electron transport chain;GO:0046185//aldehyde catabolic process;GO:1903179//regulation of dopamine biosynthetic process;GO:1905627//regulation of serotonin biosynthetic process	--
ENSG00000111276	62.419	56.152	55.435	38.779	45.117	47.298	3176	2868	2078	1462	1939	1750	CDKN1B	cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko04934//Cushing syndrome;ko05226//Gastric cancer;ko05162//Measles;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04066//HIF-1 signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko05220//Chronic myeloid leukemia	K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624;K06624	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0004860//protein kinase inhibitor activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030332//cyclin binding;GO:0030544//Hsp70 protein binding;GO:0044877//protein-containing complex binding;GO:0051087//chaperone binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0001666//response to hypoxia;GO:0001890//placenta development;GO:0006813//potassium ion transport;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007049//cell cycle;GO:0007096//regulation of exit from mitosis;GO:0007219//Notch signaling pathway;GO:0007346//regulation of mitotic cell cycle;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0008219//cell death;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010942//positive regulation of cell death;GO:0014070//response to organic cyclic compound;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0031116//positive regulation of microtubule polymerization;GO:0032355//response to estradiol;GO:0033673//negative regulation of kinase activity;GO:0042127//regulation of cell population proliferation;GO:0042326//negative regulation of phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043200//response to amino acid;GO:0043434//response to peptide hormone;GO:0045732//positive regulation of protein catabolic process;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0046686//response to cadmium ion;GO:0048102//autophagic cell death;GO:0048839//inner ear development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051271//negative regulation of cellular component movement;GO:0051726//regulation of cell cycle;GO:0060255//regulation of macromolecule metabolic process;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0071236//cellular response to antibiotic;GO:0071285//cellular response to lithium ion;GO:0071407//cellular response to organic cyclic compound;GO:0090398//cellular senescence;GO:1902746//regulation of lens fiber cell differentiation;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:1904030//negative regulation of cyclin-dependent protein kinase activity;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1905179//negative regulation of cardiac muscle tissue regeneration;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000111291	0	0.036	0	0	0	0	0	1	0	0	0	0	GPRC5D	G protein-coupled receptor class C group 5 member D [Source:HGNC Symbol;Acc:HGNC:13310]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032147//activation of protein kinase activity	--
ENSG00000111300	9.326	15.429	9.57	7.847	9.79	13.028	1005	826	652	574	750	693	NAA25	"N-alpha-acetyltransferase 25, NatB auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:25783]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031416//NatB complex	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding	GO:0017196//N-terminal peptidyl-methionine acetylation	--
ENSG00000111305	0.117	0	0.027	0	0	0	4	0	1	0	0	0	GSG1	germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0070063//RNA polymerase binding	-	--
ENSG00000111319	2.32	1.706	2.1	1.943	1.376	1.199	156	121	106	63	74	63	SCNN1A	sodium channel epithelial 1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:10599]	Organismal Systems;Organismal Systems	Sensory system;Excretory system	ko04742//Taste transduction;ko04960//Aldosterone-regulated sodium reabsorption	K04824;K04824	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0034706//sodium channel complex;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0097228//sperm principal piece	GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0050699//WW domain binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0008217//regulation of blood pressure;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0036254//cellular response to amiloride;GO:0050891//multicellular organismal water homeostasis;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050914//sensory perception of salty taste;GO:0050915//sensory perception of sour taste;GO:0055078//sodium ion homeostasis;GO:0071468//cellular response to acidic pH;GO:0098719//sodium ion import across plasma membrane;GO:1904045//cellular response to aldosterone;GO:1904117//cellular response to vasopressin	--
ENSG00000111321	30.835	35.654	32.228	33.496	34.872	33.092	1332	1525	1042	1082	1301	1052	LTBR	lymphotoxin beta receptor [Source:HGNC Symbol;Acc:HGNC:6718]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Cancer: overview;Signal transduction;Immune system;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04064//NF-kappa B signaling pathway;ko04672//Intestinal immune network for IgA production;ko04066//HIF-1 signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K03159;K03159;K03159;K03159;K03159;K03159;K03159	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0043011//myeloid dendritic cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade;GO:0048534//hematopoietic or lymphoid organ development;GO:0071260//cellular response to mechanical stimulus;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000111325	4.755	5.927	5.759	6.329	5.919	5.479	167.22	199.63	144.58	167.3	172.2	136.09	OGFOD2	2-oxoglutarate and iron dependent oxygenase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25823]	-	-	-	-	-	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	-	--
ENSG00000111328	73.995	72.831	67.898	56.116	54.895	63.208	2111.3	2075.4	1436.17	1178.23	1321.16	1309.5	CDK2AP1	cyclin dependent kinase 2 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:14002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0070182//DNA polymerase binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006261//DNA-dependent DNA replication;GO:0007049//cell cycle	--
ENSG00000111331	1.097	1.161	1.639	1.687	0.881	1.214	126	161	144	134	100	102	OAS3	2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05160//Hepatitis C;ko05162//Measles	K14216;K14216;K14216;K14216;K14216;K14216;K14216	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006139//nucleobase-containing compound metabolic process;GO:0009615//response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035395//negative regulation of chemokine (C-X-C motif) ligand 9 production;GO:0039529//RIG-I signaling pathway;GO:0039530//MDA-5 signaling pathway;GO:0042742//defense response to bacterium;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0060700//regulation of ribonuclease activity;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0071659//negative regulation of IP-10 production;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000111335	0.049	0.172	0.122	0.076	0.116	0.094	2	10	6	4	5	4	OAS2	2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05160//Hepatitis C;ko05162//Measles	K14216;K14216;K14216;K14216;K14216;K14216;K14216	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006401//RNA catabolic process;GO:0009615//response to virus;GO:0009617//response to bacterium;GO:0032728//positive regulation of interferon-beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042742//defense response to bacterium;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060700//regulation of ribonuclease activity;GO:0070106//interleukin-27-mediated signaling pathway;GO:1903487//regulation of lactation	--
ENSG00000111339	0.179	0.143	0.186	0.025	0	0	8	10	5	2	0	0	ART4	ADP-ribosyltransferase 4 (inactive) (Dombrock blood group) [Source:HGNC Symbol;Acc:HGNC:726]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106274//NAD+-protein-arginine ADP-ribosyltransferase activity;GO:0106275//NADP+-protein-arginine ADP-ribosyltransferase activity	GO:0006471//protein ADP-ribosylation;GO:0006525//arginine metabolic process;GO:0018120//peptidyl-arginine ADP-ribosylation	--
ENSG00000111341	20.184	27.578	14.481	4.603	10.795	4.614	476	684	222	90	174	67	MGP	matrix Gla protein [Source:HGNC Symbol;Acc:HGNC:7060]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008147//structural constituent of bone	GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0030154//cell differentiation;GO:0030500//regulation of bone mineralization;GO:0051216//cartilage development	--
ENSG00000111344	1.086	1.124	0.889	0.676	0.608	1.072	77	82	47	35	37	55	RASAL1	RAS protein activator like 1 [Source:HGNC Symbol;Acc:HGNC:9873]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17632	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005096//GTPase activator activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000111348	1.104	0.868	0.413	0.143	0.632	0.062	26	20	3	2	13	1	ARHGDIB	Rho GDP dissociation inhibitor beta [Source:HGNC Symbol;Acc:HGNC:679]	Organismal Systems;Organismal Systems	Nervous system;Excretory system	ko04722//Neurotrophin signaling pathway;ko04962//Vasopressin-regulated water reabsorption	K12462;K12462	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0003924//GTPase activity;GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007162//negative regulation of cell adhesion;GO:0007266//Rho protein signal transduction;GO:0007275//multicellular organism development;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:1901164//negative regulation of trophoblast cell migration;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000111358	8.39	6.869	7.126	7.596	5.642	6.982	331	300	215.08	229	229	183	GTF2H3	general transcription factor IIH subunit 3 [Source:HGNC Symbol;Acc:HGNC:4657]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Transcription;Replication and repair	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K03143;K03143;K03143	GO:0000438//core TFIIH complex portion of holo TFIIH complex;GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0097550//transcription preinitiation complex	GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding	"GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain"	--
ENSG00000111361	14.314	14.545	14.099	12.889	12.932	12.932	703.43	718	509	468.59	532.3	462	EIF2B1	eukaryotic translation initiation factor 2B subunit alpha [Source:HGNC Symbol;Acc:HGNC:3257]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K03239	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0014003//oligodendrocyte development;GO:0043434//response to peptide hormone;GO:0044237//cellular metabolic process;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000111364	4.198	4.402	4.144	3.996	4.091	4.495	205.57	231	147	140.41	177.7	155	DDX55	DEAD-box helicase 55 [Source:HGNC Symbol;Acc:HGNC:20085]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000111371	17.648	14.145	11.203	12.942	14.152	19.491	2458	1992	1106	1310	1551	2021	SLC38A1	solute carrier family 38 member 1 [Source:HGNC Symbol;Acc:HGNC:13447]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04724//Glutamatergic synapse;ko04727//GABAergic synapse	K14990;K14990	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome;GO:0098591//external side of apical plasma membrane	GO:0005283//amino acid:sodium symporter activity;GO:0005295//neutral amino acid:sodium symporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015293//symporter activity	GO:0001504//neurotransmitter uptake;GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0006868//glutamine transport;GO:0007565//female pregnancy;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000111404	0	0	0	0	0	0	0	0	0	0	0	0	RERGL	RERG like [Source:HGNC Symbol;Acc:HGNC:26213]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity	-	--
ENSG00000111405	0.096	0	0	0.084	0	0.044	3	0	0	3	0	1	ENDOU	"endonuclease, poly(U) specific [Source:HGNC Symbol;Acc:HGNC:14369]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005044//scavenger receptor activity;GO:0008083//growth factor activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0030145//manganese ion binding;GO:0030247//polysaccharide binding;GO:0046872//metal ion binding	"GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000111412	19.006	20.248	15.55	16.985	17.68	19.181	2007	2076	1462	1355	1643	1470	SPRING1	SREBF pathway regulator in golgi 1 [Source:HGNC Symbol;Acc:HGNC:26128]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:2000640//positive regulation of SREBP signaling pathway	--
ENSG00000111424	0.23	0.407	0.085	0.48	0.325	0.175	19	29	6	17	25	9	VDR	vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Cancer: overview;Endocrine system;Digestive system;Excretory system	"ko05152//Tuberculosis;ko05207//Chemical carcinogenesis - receptor activation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption"	K08539;K08539;K08539;K08539;K08539	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043235//receptor complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0038186//lithocholic acid receptor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:0070644//vitamin D response element binding;GO:1902098//calcitriol binding;GO:1902121//lithocholic acid binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007595//lactation;GO:0008285//negative regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010839//negative regulation of keratinocyte proliferation;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030522//intracellular receptor signaling pathway;GO:0038183//bile acid signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046697//decidualization;GO:0050892//intestinal absorption;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0060558//regulation of calcidiol 1-monooxygenase activity;GO:0060745//mammary gland branching involved in pregnancy;GO:0070561//vitamin D receptor signaling pathway;GO:0070564//positive regulation of vitamin D receptor signaling pathway"	THR-like
ENSG00000111432	0.029	0	0	0	0.035	0	2	0	0	0	2	0	FZD10	frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0042813//Wnt-activated receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0032956//regulation of actin cytoskeleton organization;GO:0034260//negative regulation of GTPase activity;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0060070//canonical Wnt signaling pathway;GO:0071300//cellular response to retinoic acid	--
ENSG00000111445	6.283	5.363	5.941	5.699	4.076	6.032	228	228	174	155	149	187	RFC5	replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03430//Mismatch repair	K10756;K10756;K10756	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex;GO:0031390//Ctf18 RFC-like complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0032508//DNA duplex unwinding;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000111450	7.501	6.532	7.057	6.551	6.569	7.048	531	464	370	341	394	364	STX2	syntaxin 2 [Source:HGNC Symbol;Acc:HGNC:3403]	Organismal Systems;Genetic Information Processing	"Nervous system;Folding, sorting and degradation"	ko04721//Synaptic vesicle cycle;ko04130//SNARE interactions in vesicular transport	K08486;K08486	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0031201//SNARE complex;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048787//presynaptic active zone membrane	GO:0000149//SNARE binding;GO:0005198//structural molecule activity;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0007165//signal transduction;GO:0007340//acrosome reaction;GO:0007398//ectoderm development;GO:0009887//animal organ morphogenesis;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0034599//cellular response to oxidative stress;GO:0048278//vesicle docking;GO:1903575//cornified envelope assembly	--
ENSG00000111452	0	0.06	0	0.045	0.079	0	0	2	0	2	4	0	ADGRD1	adhesion G protein-coupled receptor D1 [Source:HGNC Symbol;Acc:HGNC:19893]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000111481	73.902	79.258	85.667	84.401	78.463	92.882	2474	2768	2115	2117	2256	2322	COPZ1	COPI coat complex subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:2243]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	-	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:1901998//toxin transport"	--
ENSG00000111490	9.808	9.96	10.759	9.811	8.625	9.589	1276.23	1283.22	1029.92	884.86	970.41	912.77	TBC1D30	TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0036064//ciliary basal body	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0043547//positive regulation of GTPase activity;GO:0090630//activation of GTPase activity;GO:1902018//negative regulation of cilium assembly	--
ENSG00000111530	28.538	21.921	22.063	19.367	18.251	20.734	3889	3099	2307	1963	2337	2103	CAND1	cullin associated and neddylation dissociated 1 [Source:HGNC Symbol;Acc:HGNC:30688]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0017025//TBP-class protein binding	"GO:0010265//SCF complex assembly;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0043086//negative regulation of catalytic activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045899//positive regulation of RNA polymerase II transcription preinitiation complex assembly"	--
ENSG00000111536	0	0	0	0	0	0	0	0	0	0	0	0	IL26	interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05446	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol	GO:0005125//cytokine activity	GO:0001819//positive regulation of cytokine production;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000111537	0	0	0	0	0	0	0	0	0	0	0	0	IFNG	interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases	"Infectious disease: viral;Cancer: overview;Signaling molecules and interaction;Infectious disease: bacterial;Immune disease;Immune system;Infectious disease: viral;Infectious disease: parasitic;Signal transduction;Cell growth and death;Immune disease;Infectious disease: viral;Infectious disease: parasitic;Cardiovascular disease;Development and regeneration;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Immune disease;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Immune system;Signal transduction;Immune system;Immune disease;Infectious disease: parasitic;Folding, sorting and degradation;Endocrine and metabolic disease;Immune disease"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05322//Systemic lupus erythematosus;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko05146//Amoebiasis;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05323//Rheumatoid arthritis;ko05160//Hepatitis C;ko05140//Leishmaniasis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04066//HIF-1 signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko05143//African trypanosomiasis;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04350//TGF-beta signaling pathway;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko05144//Malaria;ko03050//Proteasome;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687;K04687	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005133//interferon-gamma receptor binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001774//microglial cell activation;GO:0001819//positive regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002281//macrophage activation involved in immune response;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008284//positive regulation of cell population proliferation;GO:0009615//response to virus;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010835//regulation of protein ADP-ribosylation;GO:0030225//macrophage differentiation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032700//negative regulation of interleukin-17 production;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032834//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0040008//regulation of growth;GO:0042307//positive regulation of protein import into nucleus;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045672//positive regulation of osteoclast differentiation;GO:0045821//positive regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048143//astrocyte activation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050769//positive regulation of neurogenesis;GO:0050796//regulation of insulin secretion;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051173//positive regulation of nitrogen compound metabolic process;GO:0051607//defense response to virus;GO:0051712//positive regulation of killing of cells of other organism;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060550//positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity;GO:0060552//positive regulation of fructose 1,6-bisphosphate metabolic process;GO:0060557//positive regulation of vitamin D biosynthetic process;GO:0060559//positive regulation of calcidiol 1-monooxygenase activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090312//positive regulation of protein deacetylation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:0150076//neuroinflammatory response;GO:1900222//negative regulation of amyloid-beta clearance;GO:1901216//positive regulation of neuron death;GO:1901857//positive regulation of cellular respiration;GO:1902004//positive regulation of amyloid-beta formation;GO:1902948//negative regulation of tau-protein kinase activity;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903543//positive regulation of exosomal secretion;GO:1904440//positive regulation of iron ion import across plasma membrane;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:1904798//positive regulation of core promoter binding;GO:2000273//positive regulation of signaling receptor activity;GO:2000309//positive regulation of tumor necrosis factor (ligand) superfamily member 11 production"	--
ENSG00000111540	60.826	60.659	62.111	64.608	65.343	70.832	4086	4146	3177	3283	3800	3544	RAB5B	"RAB5B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9784]"	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Infectious disease: parasitic;Excretory system	ko05132//Salmonella infection;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko04145//Phagosome;ko05146//Amoebiasis;ko04962//Vasopressin-regulated water reabsorption	K07888;K07888;K07888;K07888;K07888;K07888;K07888	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030667//secretory granule membrane;GO:0031901//early endosome membrane;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0030742//GTP-dependent protein binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0015031//protein transport;GO:0019882//antigen processing and presentation;GO:0030100//regulation of endocytosis;GO:0048227//plasma membrane to endosome transport	--
ENSG00000111554	4.48	3.711	4.159	3.735	4.529	4.449	247	215	166	151	199	174	MDM1	Mdm1 nuclear protein [Source:HGNC Symbol;Acc:HGNC:29917]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0046600//negative regulation of centriole replication;GO:0060041//retina development in camera-type eye	--
ENSG00000111581	11.497	8.274	8.498	7.822	7.64	8.012	547	473	332	273	330	260	NUP107	nucleoporin 107 [Source:HGNC Symbol;Acc:HGNC:29914]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14301;K14301	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery"	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	"GO:0000973//posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006355//regulation of transcription, DNA-templated;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0008585//female gonad development;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly;GO:0072006//nephron development"	--
ENSG00000111596	20.796	18.959	18.175	16.823	16.72	22.083	1053	901	649	568	705	774	CNOT2	CCR4-NOT transcription complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:7878]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12605	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex	GO:0001222//transcription corepressor binding;GO:0003712//transcription coregulator activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001829//trophectodermal cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006417//regulation of translation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0031047//gene silencing by RNA;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:2000036//regulation of stem cell population maintenance"	--
ENSG00000111602	8.322	7.484	7.564	5.996	6.13	7.042	818	732	547	443	501	494	TIMELESS	timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031298//replication fork protection complex;GO:0035861//site of double-strand break	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000076//DNA replication checkpoint signaling;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002009//morphogenesis of an epithelium;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007623//circadian rhythm;GO:0009582//detection of abiotic stimulus;GO:0030324//lung development;GO:0042752//regulation of circadian rhythm;GO:0043111//replication fork arrest;GO:0044770//cell cycle phase transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048478//replication fork protection;GO:0048511//rhythmic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051301//cell division;GO:0072711//cellular response to hydroxyurea;GO:0072719//cellular response to cisplatin;GO:1904976//cellular response to bleomycin;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000781//positive regulation of double-strand break repair"	--
ENSG00000111605	17.123	15.694	15.116	15.018	14.492	18.919	1190	1116	811	741	883	948	CPSF6	cleavage and polyadenylation specific factor 6 [Source:HGNC Symbol;Acc:HGNC:13871]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14398	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005726//perichromatin fibrils;GO:0005737//cytoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005849//mRNA cleavage factor complex;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0035061//interchromatin granule;GO:0042382//paraspeckles;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding;GO:1990448//exon-exon junction complex binding	GO:0006397//mRNA processing;GO:0031124//mRNA 3'-end processing;GO:0046833//positive regulation of RNA export from nucleus;GO:0051262//protein tetramerization;GO:0051290//protein heterotetramerization;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0110104//mRNA alternative polyadenylation;GO:1990120//messenger ribonucleoprotein complex assembly	--
ENSG00000111615	8.257	5.353	6.342	3.956	6.113	4.651	696.05	547.27	440.18	277.34	389.17	375.07	KRR1	KRR1 small subunit processome component homolog [Source:HGNC Symbol;Acc:HGNC:5176]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0032040//small-subunit processome;GO:0045171//intercellular bridge	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000111639	38.64	37.056	42.024	40.667	35.179	37.725	673	656	515	541	525	485	MRPL51	mitochondrial ribosomal protein L51 [Source:HGNC Symbol;Acc:HGNC:14044]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000111640	1988.802	2107.007	2089.399	2607.348	2425.458	2247.847	52980	56417	41116	51465	54598	43564	GAPDH	glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05010//Alzheimer disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05415//Diabetic cardiomyopathy;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K00134;K00134;K00134;K00134;K00134;K00134;K00134;K00134;K00134	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097452//GAIT complex;GO:1990904//ribonucleoprotein complex	"GO:0000166//nucleotide binding;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016740//transferase activity;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0035605//peptidyl-cysteine S-nitrosylase activity;GO:0042802//identical protein binding;GO:0050661//NADP binding;GO:0051287//NAD binding;GO:0097718//disordered domain specific binding"	GO:0000226//microtubule cytoskeleton organization;GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0010951//negative regulation of endopeptidase activity;GO:0016241//regulation of macroautophagy;GO:0017148//negative regulation of translation;GO:0031640//killing of cells of other organism;GO:0032481//positive regulation of type I interferon production;GO:0035606//peptidyl-cysteine S-trans-nitrosylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0050821//protein stabilization;GO:0050832//defense response to fungus;GO:0051402//neuron apoptotic process;GO:0051873//killing by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071346//cellular response to interferon-gamma	--
ENSG00000111641	9.538	6.709	8.284	8.969	7.177	10.85	406.72	269.57	243.19	345.99	233.7	302.72	NOP2	NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0009383//rRNA (cytosine-C5-)-methyltransferase activity;GO:0016740//transferase activity	GO:0000027//ribosomal large subunit assembly;GO:0000470//maturation of LSU-rRNA;GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0008284//positive regulation of cell population proliferation;GO:0032259//methylation;GO:0042254//ribosome biogenesis;GO:0070475//rRNA base methylation;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000111642	90.814	90.789	89.421	78.698	81.985	85.029	11523	11561	8512.46	7363	8808	7761	CHD4	chromodomain helicase DNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1919]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis	K11643;K11643	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016581//NuRD complex;GO:0032991//protein-containing complex;GO:0043233//organelle lumen;GO:0090575//RNA polymerase II transcription regulator complex"	GO:0000166//nucleotide binding;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0031492//nucleosomal DNA binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140658//ATP-dependent chromatin remodeler activity	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0010629//negative regulation of gene expression;GO:0016575//histone deacetylation;GO:0032508//DNA duplex unwinding;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000111644	1.101	0.757	0.352	0.77	1.157	0.461	25	16	8	10	21	9	ACRBP	acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001675//acrosome assembly;GO:0007286//spermatid development;GO:0008150//biological_process;GO:0009566//fertilization	--
ENSG00000111647	7.861	4.863	5.56	2.96	4.247	6.189	706	478	347	227	348	330	UHRF1BP1L	UHRF1 binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:29102]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0062069//GARP complex binding	-	--
ENSG00000111652	25.932	31.176	28.256	33.976	28.466	27.125	971	1138	749	937	894	733	COPS7A	COP9 signalosome subunit 7A [Source:HGNC Symbol;Acc:HGNC:16758]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0000338//protein deneddylation;GO:0010387//COP9 signalosome assembly;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000111653	29.39	30.082	32.692	26.15	28.725	28.294	815	816	651	529	665	524	ING4	inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0006260//DNA replication;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006473//protein acetylation;GO:0006915//apoptotic process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016570//histone modification;GO:0016573//histone acetylation;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045926//negative regulation of growth;GO:0051726//regulation of cell cycle;GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:1902749//regulation of cell cycle G2/M phase transition;GO:2000278//regulation of DNA biosynthetic process"	--
ENSG00000111664	60.764	66.649	57.431	42.852	47.724	41.589	1908.94	2114.95	1290	985.98	1274.94	938.97	GNB3	G protein subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:4400]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction	K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825;K07825	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030507//spectrin binding;GO:0051020//GTPase binding	GO:0006457//protein folding;GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0010468//regulation of gene expression;GO:0010906//regulation of glucose metabolic process;GO:0032350//regulation of hormone metabolic process;GO:0045598//regulation of fat cell differentiation;GO:0090181//regulation of cholesterol metabolic process;GO:0090207//regulation of triglyceride metabolic process;GO:1903725//regulation of phospholipid metabolic process	--
ENSG00000111665	0.802	0.916	1.431	1.971	1.649	1.604	34.06	34.05	45	48.02	50.06	39.03	CDCA3	cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0008150//biological_process;GO:0016567//protein ubiquitination;GO:0051301//cell division	--
ENSG00000111666	31	27.538	32.753	33.058	32.587	33.285	1101	962	851	873	970	862	CHPT1	choline phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:17852]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K00994;K00994;K00994;K00994;K00994	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0019992//diacylglycerol binding;GO:0046872//metal ion binding"	GO:0001558//regulation of cell growth;GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0006663//platelet activating factor biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000111667	31.458	37.206	39.904	38.661	46.441	37.69	1605	1749	1239	1317	1552	1103	USP5	ubiquitin specific peptidase 5 [Source:HGNC Symbol;Acc:HGNC:12628]	-	-	-	-	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000111669	426.128	434.05	443.169	482.265	455.332	415.112	11902	12175	9143	9997	10765	8441	TPI1	triosephosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:12009]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00562//Inositol phosphate metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism	K01803;K01803;K01803;K01803;K01803;K01803	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004807//triose-phosphate isomerase activity;GO:0005515//protein binding;GO:0008929//methylglyoxal synthase activity;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity	GO:0006006//glucose metabolic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0019242//methylglyoxal biosynthetic process;GO:0019563//glycerol catabolic process;GO:0019682//glyceraldehyde-3-phosphate metabolic process;GO:0046166//glyceraldehyde-3-phosphate biosynthetic process	--
ENSG00000111670	9.943	8.765	7.174	6.027	7.913	6.454	1178	1026	621	493	749	534	GNPTAB	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta [Source:HGNC Symbol;Acc:HGNC:29670]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K08239	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046872//metal ion binding"	GO:0007040//lysosome organization;GO:0009306//protein secretion;GO:0016256//N-glycan processing to lysosome;GO:0033299//secretion of lysosomal enzymes;GO:0046835//carbohydrate phosphorylation	--
ENSG00000111671	3.627	3.829	4.005	4.922	3.961	4.203	92	99	75	94	85	79	SPSB2	splA/ryanodine receptor domain and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:29522]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000111674	57.999	66.317	60.763	61.44	55.789	59.676	2558	2711	1879	1799	2049	1856	ENO2	enolase 2 [Source:HGNC Symbol;Acc:HGNC:3353]	Metabolism;Environmental Information Processing;Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Signal transduction;Global and overview maps;Folding, sorting and degradation;Global and overview maps;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K01689;K01689;K01689;K01689;K01689;K01689	GO:0000015//phosphopyruvate hydratase complex;GO:0001917//photoreceptor inner segment;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0009986//cell surface;GO:0016020//membrane;GO:0030426//growth cone;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0097060//synaptic membrane	GO:0000287//magnesium ion binding;GO:0004634//phosphopyruvate hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0009410//response to xenobiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0032355//response to estradiol;GO:0048609//multicellular organismal reproductive process;GO:0061621//canonical glycolysis;GO:1901214//regulation of neuron death;GO:1901215//negative regulation of neuron death	--
ENSG00000111676	36.878	37.912	39.082	36.441	40.889	47.096	3457	3564	2707	2507	3221	3214	ATN1	atrophin 1 [Source:HGNC Symbol;Acc:HGNC:3033]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0051402//neuron apoptotic process	--
ENSG00000111678	61.574	69.592	69.116	75.194	68.592	73.868	729	832	605	663	684	637	C12orf57	chromosome 12 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:29521]	-	-	-	-	GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0009791//post-embryonic development;GO:0014819//regulation of skeletal muscle contraction;GO:0021540//corpus callosum morphogenesis;GO:0021678//third ventricle development;GO:0036343//psychomotor behavior;GO:0048593//camera-type eye morphogenesis;GO:0050890//cognition	--
ENSG00000111679	6.21	6.639	6.334	7.056	6.343	7.457	274	286	201	203	216	238	PTPN6	protein tyrosine phosphatase non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: bacterial;Cancer: overview;Immune system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko05205//Proteoglycans in cancer;ko04650//Natural killer cell mediated cytotoxicity;ko04630//JAK-STAT signaling pathway;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04660//T cell receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04520//Adherens junction	K05697;K05697;K05697;K05697;K05697;K05697;K05697;K05697;K05697	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0035580//specific granule lumen;GO:0042105//alpha-beta T cell receptor complex;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0001784//phosphotyrosine residue binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0042169//SH2 domain binding;GO:0050839//cell adhesion molecule binding;GO:0140031//phosphorylation-dependent protein binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006470//protein dephosphorylation;GO:0006950//response to stress;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030220//platelet formation;GO:0031295//T cell costimulation;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0033277//abortive mitotic cell cycle;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035556//intracellular signal transduction;GO:0035855//megakaryocyte development;GO:0042130//negative regulation of T cell proliferation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042981//regulation of apoptotic process;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0045577//regulation of B cell differentiation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050853//B cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:1905867//epididymis development;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000111684	55.298	54.85	61.167	81.522	68.503	70.738	2545.87	2557.5	2071.59	2801.49	2671.93	2384.97	LPCAT3	lysophosphatidylcholine acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30244]	Metabolism;Cellular Processes	Lipid metabolism;Cell growth and death	ko00564//Glycerophospholipid metabolism;ko04216//Ferroptosis	K13515;K13515	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0071617//lysophospholipid acyltransferase activity;GO:0106262//1-acylglycerophosphoethanolamine O-acyltransferase activity;GO:0106263//1-acylglycerophosphoserine O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0030258//lipid modification;GO:0034378//chylomicron assembly;GO:0034379//very-low-density lipoprotein particle assembly;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036335//intestinal stem cell homeostasis;GO:0045540//regulation of cholesterol biosynthetic process;GO:0045797//positive regulation of intestinal cholesterol absorption;GO:0050728//negative regulation of inflammatory response;GO:0090158//endoplasmic reticulum membrane organization;GO:0097006//regulation of plasma lipoprotein particle levels;GO:1901310//positive regulation of sterol regulatory element binding protein cleavage;GO:1903573//negative regulation of response to endoplasmic reticulum stress;GO:1905885//positive regulation of triglyceride transport	--
ENSG00000111696	4.91	4.835	4.781	4.991	5.832	5.437	656	709.04	524	514	650	554.16	NT5DC3	5'-nucleotidase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30826]	-	-	-	-	GO:0043235//receptor complex	GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000111700	0	0	0	0	0	0.023	0	0	0	0	0	1	SLCO1B3	solute carrier organic anion transporter family member 1B3 [Source:HGNC Symbol;Acc:HGNC:10961]	Organismal Systems	Digestive system	ko04976//Bile secretion	K05043	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0042167//heme catabolic process;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000111701	0	0	0	0	0	0	0	0	0	0	0	0	APOBEC1	apolipoprotein B mRNA editing enzyme catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:604]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0045293//mRNA editing complex	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0046872//metal ion binding	"GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0009972//cytidine deamination;GO:0010332//response to gamma radiation;GO:0016554//cytidine to uridine editing;GO:0016556//mRNA modification;GO:0042127//regulation of cell population proliferation;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042953//lipoprotein transport;GO:0048255//mRNA stabilization;GO:0080111//DNA demethylation;GO:0090209//negative regulation of triglyceride metabolic process;GO:0090310//negative regulation of DNA methylation-dependent heterochromatin assembly;GO:1901537//positive regulation of DNA demethylation;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000111704	0	0.01	0	0	0	0	0	1.07	0	0	0	0	NANOG	Nanog homeobox [Source:HGNC Symbol;Acc:HGNC:20857]	Human Diseases;Cellular Processes	Cancer: overview;Cellular community - eukaryotes	ko05205//Proteoglycans in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells	K10164;K10164	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001714//endodermal cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030154//cell differentiation;GO:0035019//somatic stem cell population maintenance;GO:0045595//regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000648//positive regulation of stem cell proliferation"	Homeobox
ENSG00000111707	10.236	10.387	10.599	8.198	9.301	10.562	1003	1023	767	595	770	753	SUDS3	"SDS3 homolog, SIN3A corepressor complex component [Source:HGNC Symbol;Acc:HGNC:29545]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0016604//nuclear body;GO:0070822//Sin3-type complex	GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006915//apoptotic process;GO:0016575//histone deacetylation;GO:0021762//substantia nigra development;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000111711	12.546	10.148	10.69	8.866	17.151	10.486	769	671	486	421	500	444	GOLT1B	golgi transport 1B [Source:HGNC Symbol;Acc:HGNC:20175]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling"	--
ENSG00000111713	0.015	0	0	0	0	0	1	0	0	0	0	0	GYS2	glycogen synthase 2 [Source:HGNC Symbol;Acc:HGNC:4707]	Metabolism;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Cardiovascular disease;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko05415//Diabetic cardiomyopathy;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00500//Starch and sucrose metabolism	K00693;K00693;K00693;K00693;K00693;K00693;K00693;K00693	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0030864//cortical actin cytoskeleton;GO:0043265//ectoplasm	"GO:0003824//catalytic activity;GO:0004373//glycogen (starch) synthase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate"	GO:0005978//glycogen biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0008152//metabolic process;GO:0009749//response to glucose	--
ENSG00000111716	395.683	391.129	394.328	415.284	394.312	397.739	10382.76	10410.76	7830	8237.51	8585.76	7570	LDHB	lactate dehydrogenase B [Source:HGNC Symbol;Acc:HGNC:6541]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:1990204//oxidoreductase complex	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding"	GO:0006089//lactate metabolic process;GO:0006090//pyruvate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process	--
ENSG00000111725	31.014	15.628	17.982	16.432	20.488	31.701	652	719	606	558	676	465	PRKAB1	protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378]	Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04921//Oxytocin signaling pathway;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031588//nucleotide-activated protein kinase complex;GO:0032991//protein-containing complex	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding	GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007165//signal transduction;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0031669//cellular response to nutrient levels;GO:0035878//nail development;GO:0050790//regulation of catalytic activity;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000111726	21.766	22.866	23.748	20.554	19.701	25.862	748	731	564	552	598	534	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase [Source:HGNC Symbol;Acc:HGNC:18290]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K21749;K21749	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane	GO:0008781//N-acylneuraminate cytidylyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006054//N-acetylneuraminate metabolic process	--
ENSG00000111727	3.335	2.747	2.863	2.597	2.726	2.625	335	292	208	184	206	174	HCFC2	host cell factor C2 [Source:HGNC Symbol;Acc:HGNC:24972]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K14966	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016032//viral process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051568//histone H3-K4 methylation"	--
ENSG00000111728	1.685	1.075	1.71	1.147	0.853	0.879	91	65	43	33	28	44	ST8SIA1	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10869]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K03371;K03371;K03371;K03371	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0008284//positive regulation of cell population proliferation;GO:0009311//oligosaccharide metabolic process;GO:0034605//cellular response to heat;GO:0097503//sialylation	--
ENSG00000111729	0.081	0	0	0	0.044	0	1	0	0	0	1	0	CLEC4A	C-type lectin domain family 4 member A [Source:HGNC Symbol;Acc:HGNC:13257]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005509//calcium ion binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	"GO:0001818//negative regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002470//plasmacytoid dendritic cell antigen processing and presentation;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0045087//innate immune response;GO:0061760//antifungal innate immune response"	--
ENSG00000111731	7.267	6.104	6.636	5.512	5.94	8.179	658	516	443	368	453	502	C2CD5	C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0034451//centriolar satellite;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0046872//metal ion binding	GO:0010828//positive regulation of glucose transmembrane transport;GO:0015031//protein transport;GO:0031340//positive regulation of vesicle fusion;GO:0032869//cellular response to insulin stimulus;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0065002//intracellular protein transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000111732	0	0	0	0	0	0	0	0	0	0	0	0	AICDA	activation induced cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:13203]	Human Diseases;Organismal Systems	Immune disease;Immune system	ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production	K10989;K10989	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0006397//mRNA processing;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016445//somatic diversification of immunoglobulins;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016554//cytidine to uridine editing;GO:0030183//B cell differentiation;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0042742//defense response to bacterium;GO:0045190//isotype switching;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0071222//cellular response to lipopolysaccharide;GO:0080111//DNA demethylation;GO:0090310//negative regulation of DNA methylation-dependent heterochromatin assembly	--
ENSG00000111737	10.915	12.324	9.907	11.291	12.045	10.161	619	677	421	460	556	426	RAB35	"RAB35, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9774]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07876	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031253//cell projection membrane;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0045171//intercellular bridge;GO:0045334//clathrin-coated endocytic vesicle;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098993//anchored component of synaptic vesicle membrane	"GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019003//GDP binding"	GO:0000281//mitotic cytokinesis;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0019882//antigen processing and presentation;GO:0031175//neuron projection development;GO:0032456//endocytic recycling;GO:0032482//Rab protein signal transduction;GO:0036010//protein localization to endosome;GO:0048227//plasma membrane to endosome transport;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000111752	17.125	17.514	17.83	15.666	15.752	18.631	1607.17	1607.25	1311.66	1149.27	1291.18	1349.53	PHC1	polyhomeotic homolog 1 [Source:HGNC Symbol;Acc:HGNC:3182]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0016574//histone ubiquitination;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000111775	226.782	233.213	257.462	287.252	230.383	260.352	2526	2610.99	2118	2370	2167.99	2109.99	COX6A1	cytochrome c oxidase subunit 6A1 [Source:HGNC Symbol;Acc:HGNC:2277]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0030234//enzyme regulator activity	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0022900//electron transport chain;GO:0045333//cellular respiration;GO:0050790//regulation of catalytic activity;GO:1902600//proton transmembrane transport"	--
ENSG00000111780	0	0.334	0.661	0.15	0.835	0.339	0	3.84	5.59	1.27	8.08	2.82	GATC	novel protein	Metabolism;Genetic Information Processing	Global and overview maps;Translation	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis	K02435;K02435	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex	GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	GO:0006450//regulation of translational fidelity;GO:0032543//mitochondrial translation;GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation	--
ENSG00000111783	0	0	0.025	0	0	0	0	0	1	0	0	0	RFX4	regulatory factor X4 [Source:HGNC Symbol;Acc:HGNC:9985]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021537//telencephalon development;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060271//cilium assembly;GO:0070613//regulation of protein processing"	RFX
ENSG00000111785	5.748	5.65	4.742	3.223	3.672	6.052	414	351	257	185	234	246	RIC8B	RIC8 guanine nucleotide exchange factor B [Source:HGNC Symbol;Acc:HGNC:25555]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex	GO:0001965//G-protein alpha-subunit binding;GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0050790//regulation of catalytic activity	--
ENSG00000111786	57.009	59.493	64.976	54.817	56.541	59.969	1362.22	1428.87	1146.68	970.24	1141.43	1042.62	SRSF9	serine and arginine rich splicing factor 9 [Source:HGNC Symbol;Acc:HGNC:10791]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K21123;K21123	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0009636//response to toxic substance;GO:0043279//response to alkaloid;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000111790	8.168	6.472	5.715	5.521	6.677	8.329	322	287	193	155	217	221	FGFR1OP2	FGFR1 oncogene partner 2 [Source:HGNC Symbol;Acc:HGNC:23098]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0009611//response to wounding;GO:0042060//wound healing	--
ENSG00000111796	0	0	0.132	0	0	0	0	0	3	0	0	0	KLRB1	killer cell lectin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6373]	Human Diseases	Infectious disease: parasitic	ko05144//Malaria	K06543	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000111799	17.819	20.192	7.193	8.136	11.015	7.811	3335	3141	909	902	1598	941	COL12A1	collagen type XII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2188]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K08132	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005595//collagen type XII trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0030199//collagen fibril organization;GO:0035987//endodermal cell differentiation	--
ENSG00000111801	7.902	7.352	9.463	8.316	8.429	7.785	406	383.47	352	343	381	314	BTN3A3	butyrophilin subfamily 3 member A3 [Source:HGNC Symbol;Acc:HGNC:1140]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000111802	15.715	15.058	14.557	14.094	13.234	15.396	631	608	432	419	449	451	TDP2	tyrosyl-DNA phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:17768]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016235//aggresome;GO:0016604//nuclear body;GO:0016605//PML body	GO:0000287//magnesium ion binding;GO:0003697//single-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0036317//tyrosyl-RNA phosphodiesterase activity;GO:0046872//metal ion binding;GO:0070260//5'-tyrosyl-DNA phosphodiesterase activity	"GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048666//neuron development;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000111816	0.465	0.384	0.313	0.287	0.423	0.412	129	107	64	59	99	83	FRK	fyn related Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3955]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K08892	GO:0005576//extracellular region;GO:0005622//intracellular anatomical structure;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0045087//innate immune response	--
ENSG00000111817	5.889	4.859	5.762	5.452	5.605	4.899	553	397	354	329	388	324	DSE	dermatan sulfate epimerase [Source:HGNC Symbol;Acc:HGNC:21144]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K01794;K01794	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0047757//chondroitin-glucuronate 5-epimerase activity	GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030205//dermatan sulfate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030208//dermatan sulfate biosynthetic process	--
ENSG00000111832	20.608	19.519	17.039	17.045	16.869	20.383	762	694	448	401	527	576	RWDD1	RWD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20993]	-	-	-	-	GO:0005737//cytoplasm;GO:0005844//polysome	GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0007569//cell aging;GO:0030521//androgen receptor signaling pathway;GO:0034599//cellular response to oxidative stress;GO:0071394//cellular response to testosterone stimulus;GO:2000825//positive regulation of androgen receptor activity	--
ENSG00000111834	1.358	1.05	0.624	0.39	0.338	0.57	79	62	27	17	16	18	RSPH4A	radial spoke head component 4A [Source:HGNC Symbol;Acc:HGNC:21558]	-	-	-	-	GO:0001534//radial spoke;GO:0001535//radial spoke head;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0003674//molecular_function	GO:0003341//cilium movement;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility;GO:0062177//radial spoke assembly;GO:0120221//maintenance of ciliary planar beating movement pattern	--
ENSG00000111837	0.446	0.246	0.207	0.226	0.031	0.206	27	18	12	12	2	12	MAK	male germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0030496//midbody;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0042073//intraciliary transport;GO:0045494//photoreceptor cell maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0060271//cilium assembly;GO:1902856//negative regulation of non-motile cilium assembly"	--
ENSG00000111843	78.916	81.933	76.926	79.856	75.177	80.489	1675	1742	1205	1251	1344	1242	TMEM14C	transmembrane protein 14C [Source:HGNC Symbol;Acc:HGNC:20952]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0006783//heme biosynthetic process;GO:0006839//mitochondrial transport;GO:0030218//erythrocyte differentiation;GO:0070453//regulation of heme biosynthetic process	--
ENSG00000111845	6.426	6.173	6.043	4.829	5.096	5.525	203	196	141	113	136	127	PAK1IP1	PAK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20882]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0008283//cell population proliferation;GO:0009968//negative regulation of signal transduction;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0060021//roof of mouth development;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000111846	3.852	3.206	3.541	2.469	2.642	3.459	361	302	244	171	209	236	GCNT2	glucosaminyl (N-acetyl) transferase 2 (I blood group) [Source:HGNC Symbol;Acc:HGNC:4204]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K00742;K00742	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0010608//posttranscriptional regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010812//negative regulation of cell-substrate adhesion;GO:0030335//positive regulation of cell migration;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0036438//maintenance of lens transparency;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000111850	1.544	1.773	1.547	1.57	1.969	2.715	77	83	57	58	83	81	SMIM8	small integral membrane protein 8 [Source:HGNC Symbol;Acc:HGNC:21401]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000111859	4.386	4.681	3.826	4.978	5.512	6.014	400	421	249	345	396	393	NEDD9	"neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733]"	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:1990782//protein tyrosine kinase binding	GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0040008//regulation of growth;GO:0051017//actin filament bundle assembly;GO:0051301//cell division;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090527//actin filament reorganization;GO:0090630//activation of GTPase activity;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000111860	0.471	0.345	0.348	0.265	0.345	0.342	72	53	29	29	39	38	CEP85L	centrosomal protein 85 like [Source:HGNC Symbol;Acc:HGNC:21638]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0001764//neuron migration	--
ENSG00000111863	91.171	95.991	100.573	80.933	88.026	88.495	2458	2481	1922	1603	1961	1676	ADTRP	androgen dependent TFPI regulating protein [Source:HGNC Symbol;Acc:HGNC:21214]	-	-	-	-	GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002686//negative regulation of leukocyte migration;GO:0003332//negative regulation of extracellular matrix constituent secretion;GO:0006629//lipid metabolic process;GO:0010628//positive regulation of gene expression;GO:0030195//negative regulation of blood coagulation;GO:0042758//long-chain fatty acid catabolic process;GO:0043491//protein kinase B signaling;GO:0050709//negative regulation of protein secretion;GO:0071383//cellular response to steroid hormone stimulus;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:2000402//negative regulation of lymphocyte migration	--
ENSG00000111875	9.369	8.02	9.36	8.691	8.792	8.494	473	407	349	325	375	312	ASF1A	anti-silencing function 1A histone chaperone [Source:HGNC Symbol;Acc:HGNC:20995]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0001649//osteoblast differentiation;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0042692//muscle cell differentiation	--
ENSG00000111877	2.041	1.924	2.159	1.931	1.864	2.076	201	191	138	121	147	152	MCM9	minichromosome maintenance 9 homologous recombination repair factor [Source:HGNC Symbol;Acc:HGNC:21484]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0042555//MCM complex;GO:0097362//MCM8-MCM9 complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding;GO:0032406//MutLbeta complex binding;GO:0032407//MutSalpha complex binding;GO:0032408//MutSbeta complex binding;GO:0044877//protein-containing complex binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007276//gamete generation;GO:0007292//female gamete generation;GO:0032508//DNA duplex unwinding;GO:0036298//recombinational interstrand cross-link repair;GO:0070716//mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication;GO:0071168//protein localization to chromatin	--
ENSG00000111879	1.128	1.405	0.726	0.936	0.746	0.881	89	55	39	37	54	51	FAM184A	family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]	-	-	-	-	GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000111880	7.2	5.239	6.447	5.589	5.012	5.478	620	527	361	321	401	365	RNGTT	RNA guanylyltransferase and 5'-phosphatase [Source:HGNC Symbol;Acc:HGNC:10073]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K13917	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004484//mRNA guanylyltransferase activity;GO:0004651//polynucleotide 5'-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008192//RNA guanylyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0050355//triphosphatase activity	GO:0006370//7-methylguanosine mRNA capping;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006470//protein dephosphorylation;GO:0008152//metabolic process;GO:0016311//dephosphorylation;GO:0098507//polynucleotide 5' dephosphorylation	--
ENSG00000111885	9.579	8.087	8.521	7.601	7.415	9.296	997	846	655	586	652	704	MAN1A1	mannosidase alpha class 1A member 1 [Source:HGNC Symbol;Acc:HGNC:6821]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K01230;K01230;K01230;K01230	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0015923//mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0008152//metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0045047//protein targeting to ER;GO:1904381//Golgi apparatus mannose trimming;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway	--
ENSG00000111886	0.02	0.02	0	0.096	0.024	0.07	2	2	0	7	2	5	GABRR2	gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05190;K05190;K05190;K05190;K05190	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0019904//protein domain specific binding;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007601//visual perception;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport	--
ENSG00000111897	140.068	128.116	136.027	122.237	122.986	129.489	9079	8347	6512	5869	6735	6107	SERINC1	serine incorporator 1 [Source:HGNC Symbol;Acc:HGNC:13464]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0006629//lipid metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0006665//sphingolipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0044091//membrane biogenesis;GO:1904219//positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;GO:1904222//positive regulation of serine C-palmitoyltransferase activity	--
ENSG00000111906	35.999	36.702	38.661	32.265	26.633	30.865	861	937	651	551	575	548	HDDC2	HD domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21078]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K07023;K07023;K07023	-	GO:0002953//5'-deoxynucleotidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000111907	261.701	291.753	229.702	196.62	189.215	184.667	6488	7206	4173	3492	3995	3254	TPD52L1	TPD52 like 1 [Source:HGNC Symbol;Acc:HGNC:12006]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0043406//positive regulation of MAP kinase activity;GO:0046330//positive regulation of JNK cascade;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000111911	14.587	11.714	12.368	12.743	11.962	14.787	1006	812	630	651	697	742	HINT3	histidine triad nucleotide binding protein 3 [Source:HGNC Symbol;Acc:HGNC:18468]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0043530//adenosine 5'-monophosphoramidase activity	-	--
ENSG00000111912	10.589	8.998	6.587	6.227	9.973	9.295	710	570	260	342	534	448	NCOA7	nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K25442	GO:0005634//nucleus	GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006979//response to oxidative stress;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1900408//negative regulation of cellular response to oxidative stress;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1903204//negative regulation of oxidative stress-induced neuron death	--
ENSG00000111913	0.15	0.113	0.25	0.17	0.174	0.266	13	9	12	8	10	15	RIPOR2	RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030175//filopodium;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0060171//stereocilium membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0071889//14-3-3 protein binding	GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007517//muscle organ development;GO:0007605//sensory perception of sound;GO:0009968//negative regulation of signal transduction;GO:0030154//cell differentiation;GO:0035024//negative regulation of Rho protein signal transduction;GO:0042130//negative regulation of T cell proliferation;GO:0045184//establishment of protein localization;GO:0045663//positive regulation of myoblast differentiation;GO:0048741//skeletal muscle fiber development;GO:0051260//protein homooligomerization;GO:0051491//positive regulation of filopodium assembly;GO:0051726//regulation of cell cycle;GO:0060088//auditory receptor cell stereocilium organization;GO:0071260//cellular response to mechanical stimulus;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1901673//regulation of mitotic spindle assembly;GO:1901741//positive regulation of myoblast fusion;GO:1903904//negative regulation of establishment of T cell polarity;GO:1905872//negative regulation of protein localization to cell leading edge;GO:1990869//cellular response to chemokine;GO:2000114//regulation of establishment of cell polarity;GO:2000391//positive regulation of neutrophil extravasation;GO:2000405//negative regulation of T cell migration;GO:2001107//negative regulation of Rho guanyl-nucleotide exchange factor activity	--
ENSG00000111961	18.27	15.868	18.305	14.78	16.29	17.517	2742	2446	2055	1694	2120	1942	SASH1	SAM and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19182]	-	-	-	-	GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0001965//G-protein alpha-subunit binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019901//protein kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0060090//molecular adaptor activity	GO:0000209//protein polyubiquitination;GO:0010595//positive regulation of endothelial cell migration;GO:0010632//regulation of epithelial cell migration;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0043507//positive regulation of JUN kinase activity;GO:0045766//positive regulation of angiogenesis;GO:1900044//regulation of protein K63-linked ubiquitination;GO:1900745//positive regulation of p38MAPK cascade;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902498//regulation of protein autoubiquitination	--
ENSG00000111962	2.906	2.742	3.514	3.199	2.83	3.154	271	257	242	221	223	214	UST	uronyl 2-sulfotransferase [Source:HGNC Symbol;Acc:HGNC:17223]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K03193	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0006477//protein sulfation;GO:0030010//establishment of cell polarity;GO:0030208//dermatan sulfate biosynthetic process;GO:0050770//regulation of axonogenesis	--
ENSG00000111981	0.24	0.209	0.122	0.142	0.089	0.124	16	14	6	7	5	6	ULBP1	UL16 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14893]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07986	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0002376//immune system process;GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000112029	3.126	2.909	2.682	2.234	2.657	2.687	144	134	90	75	103	87	FBXO5	F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K10292	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0072687//meiotic spindle	GO:0005515//protein binding;GO:0010997//anaphase-promoting complex binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0001556//oocyte maturation;GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007057//spindle assembly involved in female meiosis I;GO:0007088//regulation of mitotic nuclear division;GO:0007346//regulation of mitotic cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016050//vesicle organization;GO:0016567//protein ubiquitination;GO:0032876//negative regulation of DNA endoreduplication;GO:0040020//regulation of meiotic nuclear division;GO:0045669//positive regulation of osteoblast differentiation;GO:0045835//negative regulation of meiotic nuclear division;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0046785//microtubule polymerization;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0070169//positive regulation of biomineral tissue development;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:1905322//positive regulation of mesenchymal stem cell migration;GO:2000773//negative regulation of cellular senescence;GO:2001021//negative regulation of response to DNA damage stimulus	--
ENSG00000112031	7.892	6.47	6.821	5.69	5.643	8.772	598	489	380	319	359	430	MTRF1L	mitochondrial translation release factor 1 like [Source:HGNC Symbol;Acc:HGNC:21051]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003747//translation release factor activity	GO:0006412//translation;GO:0006415//translational termination;GO:0070126//mitochondrial translational termination	--
ENSG00000112033	9.595	10.352	11.144	11.148	11.033	10.592	741	806	630	639	722	594	PPARD	peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235]	Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko04310//Wnt signaling pathway;ko03320//PPAR signaling pathway;ko05221//Acute myeloid leukemia	K04504;K04504;K04504;K04504	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0070539//linoleic acid binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001890//placenta development;GO:0006006//glucose metabolic process;GO:0006029//proteoglycan metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006776//vitamin A metabolic process;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0007507//heart development;GO:0007566//embryo implantation;GO:0008203//cholesterol metabolic process;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008366//axon ensheathment;GO:0008654//phospholipid biosynthetic process;GO:0009062//fatty acid catabolic process;GO:0009749//response to glucose;GO:0009755//hormone-mediated signaling pathway;GO:0010033//response to organic substance;GO:0010628//positive regulation of gene expression;GO:0010887//negative regulation of cholesterol storage;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0015908//fatty acid transport;GO:0019216//regulation of lipid metabolic process;GO:0019395//fatty acid oxidation;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030522//intracellular receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0032966//negative regulation of collagen biosynthetic process;GO:0033189//response to vitamin A;GO:0033993//response to lipid;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042311//vasodilation;GO:0043066//negative regulation of apoptotic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0043616//keratinocyte proliferation;GO:0045598//regulation of fat cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045684//positive regulation of epidermis development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045923//positive regulation of fatty acid metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046321//positive regulation of fatty acid oxidation;GO:0046697//decidualization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0051546//keratinocyte migration;GO:0051716//cellular response to stimulus;GO:0060612//adipose tissue development;GO:0071222//cellular response to lipopolysaccharide;GO:0071456//cellular response to hypoxia;GO:0097190//apoptotic signaling pathway;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1904659//glucose transmembrane transport;GO:2000288//positive regulation of myoblast proliferation"	THR-like
ENSG00000112038	0	0	0	0	0	0	0	0	0	0	0	0	OPRM1	opioid receptor mu 1 [Source:HGNC Symbol;Acc:HGNC:8156]	Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Endocrine system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04915//Estrogen signaling pathway;ko05032//Morphine addiction	K04215;K04215;K04215	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0032839//dendrite cytoplasm;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0097444//spine apparatus;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0001965//G-protein alpha-subunit binding;GO:0004930//G protein-coupled receptor activity;GO:0004979//beta-endorphin receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0031005//filamin binding;GO:0031681//G-protein beta-subunit binding;GO:0038047//morphine receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0002438//acute inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007600//sensory perception;GO:0008285//negative regulation of cell population proliferation;GO:0009314//response to radiation;GO:0019233//sensory perception of pain;GO:0031635//adenylate cyclase-inhibiting opioid receptor signaling pathway;GO:0032094//response to food;GO:0032100//positive regulation of appetite;GO:0032496//response to lipopolysaccharide;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0042060//wound healing;GO:0042220//response to cocaine;GO:0042755//eating behavior;GO:0043278//response to morphine;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0044849//estrous cycle;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045471//response to ethanol;GO:0048149//behavioral response to ethanol;GO:0050769//positive regulation of neurogenesis;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051930//regulation of sensory perception of pain;GO:0060079//excitatory postsynaptic potential;GO:0061358//negative regulation of Wnt protein secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport;GO:0070848//response to growth factor;GO:0071315//cellular response to morphine;GO:0080135//regulation of cellular response to stress;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:2000310//regulation of NMDA receptor activity"	--
ENSG00000112039	2.926	2.543	1.736	2.52	2.035	2.594	151	132	68	97	89	90	FANCE	FA complementation group E [Source:HGNC Symbol;Acc:HGNC:3586]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10892	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex	GO:0003674//molecular_function	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0036297//interstrand cross-link repair	--
ENSG00000112041	0.99	1.018	1.805	2.151	2.271	1.875	42	43	58	70	81	60	TULP1	TUB like protein 1 [Source:HGNC Symbol;Acc:HGNC:12423]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043679//axon terminus;GO:0045202//synapse	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0051015//actin filament binding"	"GO:0001895//retina homeostasis;GO:0006909//phagocytosis;GO:0006910//phagocytosis, recognition;GO:0007601//visual perception;GO:0016192//vesicle-mediated transport;GO:0016358//dendrite development;GO:0042462//eye photoreceptor cell development;GO:0045494//photoreceptor cell maintenance;GO:0050766//positive regulation of phagocytosis;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0060041//retina development in camera-type eye;GO:0061512//protein localization to cilium;GO:1903546//protein localization to photoreceptor outer segment"	Tub
ENSG00000112053	0	0	0	0	0	0	0	0	0	0	0	0	SLC26A8	solute carrier family 26 member 8 [Source:HGNC Symbol;Acc:HGNC:14468]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0007283//spermatogenesis;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation;GO:0051321//meiotic cell cycle;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000112062	13.849	14.576	13.946	13.375	12.61	13.331	1036	1141	832	769	869	784	MAPK14	mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Nervous system;Circulatory system;Infectious disease: parasitic;Cellular community - eukaryotes;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Nervous system;Signal transduction;Endocrine system;Immune system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Cancer: overview;Immune system;Endocrine system;Infectious disease: bacterial;Endocrine system;Immune system;Infectious disease: bacterial;Signal transduction	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04114//Oocyte meiosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway"	K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441	GO:0000922//spindle pole;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0034774//secretory granule lumen;GO:0098978//glutamatergic synapse;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0051525//NFAT protein binding;GO:0106310//protein serine kinase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000165//MAPK cascade;GO:0000902//cell morphogenesis;GO:0001502//cartilage condensation;GO:0001525//angiogenesis;GO:0001649//osteoblast differentiation;GO:0001890//placenta development;GO:0002021//response to dietary excess;GO:0002062//chondrocyte differentiation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007519//skeletal muscle tissue development;GO:0010628//positive regulation of gene expression;GO:0010831//positive regulation of myotube differentiation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019395//fatty acid oxidation;GO:0030168//platelet activation;GO:0030278//regulation of ossification;GO:0030316//osteoclast differentiation;GO:0031281//positive regulation of cyclase activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032495//response to muramyl dipeptide;GO:0032496//response to lipopolysaccharide;GO:0032735//positive regulation of interleukin-12 production;GO:0032868//response to insulin;GO:0035331//negative regulation of hippo signaling;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0035994//response to muscle stretch;GO:0038066//p38MAPK cascade;GO:0042307//positive regulation of protein import into nucleus;GO:0042770//signal transduction in response to DNA damage;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060348//bone development;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071356//cellular response to tumor necrosis factor;GO:0071479//cellular response to ionizing radiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090336//positive regulation of brown fat cell differentiation;GO:0090398//cellular senescence;GO:0090400//stress-induced premature senescence;GO:0098586//cellular response to virus;GO:0099179//regulation of synaptic membrane adhesion;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1901741//positive regulation of myoblast fusion;GO:2000379//positive regulation of reactive oxygen species metabolic process"	--
ENSG00000112077	0	0	0	0	0	0	0	0	0	0	0	0	RHAG	Rh associated glycoprotein [Source:HGNC Symbol;Acc:HGNC:10006]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity;GO:0022840//leak channel activity;GO:0030506//ankyrin binding;GO:0035379//carbon dioxide transmembrane transporter activity	GO:0006873//cellular ion homeostasis;GO:0015670//carbon dioxide transport;GO:0015696//ammonium transport;GO:0015701//bicarbonate transport;GO:0035378//carbon dioxide transmembrane transport;GO:0048821//erythrocyte development;GO:0060586//multicellular organismal iron ion homeostasis;GO:0072488//ammonium transmembrane transport;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000112078	25.725	25.958	19.053	22.263	24.337	22.545	2763	2749	1470	1704	2216	1705.58	KCTD20	potassium channel tetramerization domain containing 20 [Source:HGNC Symbol;Acc:HGNC:21052]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0042327//positive regulation of phosphorylation	--
ENSG00000112079	18.168	16.898	17.353	15.977	16.395	19.832	1351	1263	953	880	1030	1073	STK38	serine/threonine kinase 38 [Source:HGNC Symbol;Acc:HGNC:17847]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0043407//negative regulation of MAP kinase activity	--
ENSG00000112081	68.605	65.016	62.322	54.533	54.451	63.677	2862	2744	2140	1769	2135	1835	SRSF3	serine and arginine rich splicing factor 3 [Source:HGNC Symbol;Acc:HGNC:10785]	Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Transcription	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12892;K12892;K12892	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043274//phospholipase binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0051028//mRNA transport;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000112096	92.192	82.825	105.744	90.884	96.546	92.953	4334.8	4196.28	3536.98	3114.06	3681.82	3293.02	SOD2	superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems	Neurodegenerative disease;Cancer: overview;Cardiovascular disease;Signal transduction;Aging;Transport and catabolism;Aging	ko05016//Huntington disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko04068//FoxO signaling pathway;ko04211//Longevity regulating pathway;ko04146//Peroxisome;ko04213//Longevity regulating pathway - multiple species	K04564;K04564;K04564;K04564;K04564;K04564;K04564	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0004784//superoxide dismutase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0000302//response to reactive oxygen species;GO:0000303//response to superoxide;GO:0001306//age-dependent response to oxidative stress;GO:0001315//age-dependent response to reactive oxygen species;GO:0001666//response to hypoxia;GO:0001836//release of cytochrome c from mitochondria;GO:0001889//liver development;GO:0003032//detection of oxygen;GO:0003069//acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006749//glutathione metabolic process;GO:0006801//superoxide metabolic process;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0007507//heart development;GO:0007568//aging;GO:0007626//locomotory behavior;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0008637//apoptotic mitochondrial changes;GO:0009314//response to radiation;GO:0009409//response to cold;GO:0009410//response to xenobiotic stimulus;GO:0009791//post-embryonic development;GO:0010042//response to manganese ion;GO:0010043//response to zinc ion;GO:0010269//response to selenium ion;GO:0010332//response to gamma radiation;GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:0014823//response to activity;GO:0019430//removal of superoxide radicals;GO:0022904//respiratory electron transport chain;GO:0030097//hemopoiesis;GO:0030335//positive regulation of cell migration;GO:0031667//response to nutrient levels;GO:0032364//oxygen homeostasis;GO:0032496//response to lipopolysaccharide;GO:0033591//response to L-ascorbic acid;GO:0034021//response to silicon dioxide;GO:0035900//response to isolation stress;GO:0035902//response to immobilization stress;GO:0042311//vasodilation;GO:0042542//response to hydrogen peroxide;GO:0042554//superoxide anion generation;GO:0042743//hydrogen peroxide metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045599//negative regulation of fat cell differentiation;GO:0046686//response to cadmium ion;GO:0048147//negative regulation of fibroblast proliferation;GO:0048666//neuron development;GO:0048678//response to axon injury;GO:0048773//erythrophore differentiation;GO:0050665//hydrogen peroxide biosynthetic process;GO:0050790//regulation of catalytic activity;GO:0051289//protein homotetramerization;GO:0051602//response to electrical stimulus;GO:0051881//regulation of mitochondrial membrane potential;GO:0055072//iron ion homeostasis;GO:0055093//response to hyperoxia;GO:0071000//response to magnetism;GO:0071361//cellular response to ethanol;GO:0072593//reactive oxygen species metabolic process;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1902631//negative regulation of membrane hyperpolarization;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process;GO:1905932//positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	--
ENSG00000112110	19.235	17.406	18.237	17.513	19.12	20.151	387	352	271	261	325	295	MRPL18	mitochondrial ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:14477]	Genetic Information Processing	Translation	ko03010//Ribosome	K02881	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008097//5S rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation;GO:0035928//rRNA import into mitochondrion	--
ENSG00000112115	0	0	0	0	0	0	0	0	0	0	0	0	IL17A	interleukin 17A [Source:HGNC Symbol;Acc:HGNC:5981]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune disease;Endocrine and metabolic disease;Immune system;Immune system;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko05323//Rheumatoid arthritis;ko04936//Alcoholic liver disease;ko04659//Th17 cell differentiation;ko04657//IL-17 signaling pathway;ko05321//Inflammatory bowel disease	K05489;K05489;K05489;K05489;K05489;K05489	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0002225//positive regulation of antimicrobial peptide production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007219//Notch signaling pathway;GO:0007267//cell-cell signaling;GO:0008219//cell death;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032739//positive regulation of interleukin-16 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0045087//innate immune response;GO:0045672//positive regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0060729//intestinal epithelial structure maintenance;GO:0071347//cellular response to interleukin-1;GO:0072537//fibroblast activation;GO:0097400//interleukin-17-mediated signaling pathway;GO:0097530//granulocyte migration;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1903348//positive regulation of bicellular tight junction assembly;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production	--
ENSG00000112116	0	0	0	0	0	0	0	0	0	0	0	0	IL17F	interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Immune system;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04659//Th17 cell differentiation;ko04657//IL-17 signaling pathway;ko05321//Inflammatory bowel disease	K05494;K05494;K05494;K05494	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0001819//positive regulation of cytokine production;GO:0002225//positive regulation of antimicrobial peptide production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0016525//negative regulation of angiogenesis;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0032645//regulation of granulocyte macrophage colony-stimulating factor production;GO:0032663//regulation of interleukin-2 production;GO:0032675//regulation of interleukin-6 production;GO:0032677//regulation of interleukin-8 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032761//positive regulation of lymphotoxin A production;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051216//cartilage development;GO:0097400//interleukin-17-mediated signaling pathway;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production	--
ENSG00000112118	19.609	20.689	19.871	13.642	14.529	13.513	1171	1270	905	583	775	593	MCM3	minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02541;K02541	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005658//alpha DNA polymerase:primase complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0042555//MCM complex;GO:0048471//perinuclear region of cytoplasm;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0007049//cell cycle;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:1902975//mitotic DNA replication initiation	--
ENSG00000112130	10.105	9.829	9.339	8.423	9.069	9.436	349	383	251	208	270	258	RNF8	ring finger protein 8 [Source:HGNC Symbol;Acc:HGNC:10071]	-	-	-	-	"GO:0000151//ubiquitin ligase complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030496//midbody;GO:0035861//site of double-strand break"	GO:0003682//chromatin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007286//spermatid development;GO:0010212//response to ionizing radiation;GO:0016567//protein ubiquitination;GO:0033522//histone H2A ubiquitination;GO:0033523//histone H2B ubiquitination;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0036297//interstrand cross-link repair;GO:0043486//histone exchange;GO:0045190//isotype switching;GO:0045739//positive regulation of DNA repair;GO:0051301//cell division;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070535//histone H2A K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination"	--
ENSG00000112137	7.657	7.426	7.459	5.452	6.96	7.327	731	718	516	415	575	559	PHACTR1	phosphatase and actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:20990]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse	GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity	GO:0021987//cerebral cortex development;GO:0030036//actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization;GO:0043086//negative regulation of catalytic activity;GO:0043149//stress fiber assembly;GO:0048870//cell motility;GO:0050790//regulation of catalytic activity;GO:0140059//dendrite arborization;GO:2001222//regulation of neuron migration	--
ENSG00000112139	0.556	1.149	0.505	0.349	0.917	0.464	60	83	61	49	75	41	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1 [Source:HGNC Symbol;Acc:HGNC:19267]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane;GO:0098982//GABA-ergic synapse	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007399//nervous system development;GO:0007420//brain development;GO:0021527//spinal cord association neuron differentiation;GO:0021799//cerebral cortex radially oriented cell migration;GO:0030154//cell differentiation;GO:0099179//regulation of synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000112144	6.295	5.025	5.714	3.897	3.909	6.307	803	644	538	368	421	585	CILK1	ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0035556//intracellular signal transduction;GO:0035720//intraciliary anterograde transport;GO:0035721//intraciliary retrograde transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly	--
ENSG00000112146	21.354	20.176	19.184	19.755	17.67	22.381	1056	919	676	704	776	770	FBXO9	F-box protein 9 [Source:HGNC Symbol;Acc:HGNC:13588]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032006//regulation of TOR signaling;GO:0045087//innate immune response;GO:0045444//fat cell differentiation	--
ENSG00000112149	5.012	5.542	4.346	2.712	3.541	2.619	242	269	155	97	144	92	CD83	CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	"GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0014070//response to organic cyclic compound;GO:0032713//negative regulation of interleukin-4 production;GO:0032733//positive regulation of interleukin-10 production;GO:0032743//positive regulation of interleukin-2 production;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation"	--
ENSG00000112159	3.564	3.386	3.002	2.299	2.531	2.645	1361	1305	850	653	816	738	MDN1	midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14572	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030687//preribosome, large subunit precursor;GO:0045111//intermediate filament cytoskeleton"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing	--
ENSG00000112164	0.014	0	0	0	0.009	0	2	0	0	0	1	0	GLP1R	glucagon like peptide 1 receptor [Source:HGNC Symbol;Acc:HGNC:4324]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04911//Insulin secretion	K04581;K04581;K04581	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004967//glucagon receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0044508//glucagon-like peptide 1 receptor activity	"GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007611//learning or memory;GO:0008016//regulation of heart contraction;GO:0019933//cAMP-mediated signaling;GO:0031204//posttranslational protein targeting to membrane, translocation;GO:0045776//negative regulation of blood pressure;GO:0045777//positive regulation of blood pressure;GO:0046879//hormone secretion;GO:0071377//cellular response to glucagon stimulus;GO:1990911//response to psychosocial stress"	--
ENSG00000112167	5.017	4.682	6.576	5.967	5.203	4.928	210	197	203	185	184	150	SAYSD1	SAYSVFN motif domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21025]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000112175	0	0.048	0	0.016	0.014	0.017	0	4	0	1	1	1	BMP5	bone morphogenetic protein 5 [Source:HGNC Symbol;Acc:HGNC:1072]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K04663;K04663;K04663	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031982//vesicle	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0070700//BMP receptor binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0003272//endocardial cushion formation;GO:0003323//type B pancreatic cell development;GO:0003344//pericardium morphogenesis;GO:0007165//signal transduction;GO:0007389//pattern specification process;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010894//negative regulation of steroid biosynthetic process;GO:0021502//neural fold elevation formation;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030539//male genitalia development;GO:0030902//hindbrain development;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0043583//ear development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048738//cardiac muscle tissue development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0060037//pharyngeal system development;GO:0060395//SMAD protein signal transduction;GO:0060411//cardiac septum morphogenesis;GO:0060710//chorio-allantoic fusion;GO:0061384//heart trabecula morphogenesis;GO:0071676//negative regulation of mononuclear cell migration;GO:0097065//anterior head development;GO:1900006//positive regulation of dendrite development;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1905069//allantois development;GO:2000065//negative regulation of cortisol biosynthetic process	--
ENSG00000112182	0.943	1.065	0.9	0.727	1.028	0.62	162	148	127	103	119	81	BACH2	BTB domain and CNC homolog 2 [Source:HGNC Symbol;Acc:HGNC:14078]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0051170//import into nucleus;GO:0090721//primary adaptive immune response involving T cells and B cells"	TF_bZIP
ENSG00000112183	7.234	9.317	8.638	10.293	10.908	10.843	383	438	284	353	423	396	RBM24	RNA binding motif protein 24 [Source:HGNC Symbol;Acc:HGNC:21539]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0097157//pre-mRNA intronic binding;GO:1990715//mRNA CDS binding;GO:1990825//sequence-specific mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0003197//endocardial cushion development;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0010830//regulation of myotube differentiation;GO:0010831//positive regulation of myotube differentiation;GO:0030154//cell differentiation;GO:0043488//regulation of mRNA stability;GO:0045663//positive regulation of myoblast differentiation;GO:0048255//mRNA stabilization;GO:0061157//mRNA destabilization;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:1902811//positive regulation of skeletal muscle fiber differentiation;GO:1905870//positive regulation of 3'-UTR-mediated mRNA stabilization;GO:2000738//positive regulation of stem cell differentiation;GO:2000766//negative regulation of cytoplasmic translation"	--
ENSG00000112186	32.704	29.357	24.271	29.169	28.388	30.398	1763	1665	1015	1146	1297	1197	CAP2	cyclase associated actin cytoskeleton regulatory protein 2 [Source:HGNC Symbol;Acc:HGNC:20039]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0042802//identical protein binding	GO:0000902//cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity;GO:0019933//cAMP-mediated signaling;GO:0045761//regulation of adenylate cyclase activity	--
ENSG00000112195	0	0	0.034	0	0	0	0	0	2	0	0	0	TREML2	triggering receptor expressed on myeloid cells like 2 [Source:HGNC Symbol;Acc:HGNC:21092]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0042110//T cell activation	--
ENSG00000112200	5.986	4.395	5.908	4.303	3.521	4.144	669	476	388	285	325	347	ZNF451	zinc finger protein 451 [Source:HGNC Symbol;Acc:HGNC:21091]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016605//PML body	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061665//SUMO ligase activity	GO:0010468//regulation of gene expression;GO:0016925//protein sumoylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:2000616//negative regulation of histone H3-K9 acetylation	--
ENSG00000112208	3.566	2.647	3.207	2.91	2.922	3.347	491.91	367.04	326.74	297.34	340.57	335.94	BAG2	BAG cochaperone 2 [Source:HGNC Symbol;Acc:HGNC:938]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09556	GO:0005829//cytosol;GO:0005874//microtubule;GO:0030424//axon;GO:0030425//dendrite;GO:0101031//chaperone complex;GO:1901588//dendritic microtubule	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0048156//tau protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0010954//positive regulation of protein processing;GO:0019538//protein metabolic process;GO:0031397//negative regulation of protein ubiquitination;GO:0032091//negative regulation of protein binding;GO:0050821//protein stabilization;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000112210	8.177	7.4	7.205	3.715	5.066	6.184	521.09	483.96	339.26	177.66	283.43	289.06	RAB23	"RAB23, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14263]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030054//cell junction;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport;GO:0006968//cellular defense response;GO:0015031//protein transport;GO:0042308//negative regulation of protein import into nucleus;GO:0046039//GTP metabolic process;GO:0060271//cilium assembly;GO:0097094//craniofacial suture morphogenesis	--
ENSG00000112212	0	0	0	0	0	0	0	0	0	0	0	0	TSPO2	translocator protein 2 [Source:HGNC Symbol;Acc:HGNC:21256]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes	Signaling molecules and interaction;Infectious disease: viral;Digestive system;Cell growth and death	ko04080//Neuroactive ligand-receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04979//Cholesterol metabolism;ko04214//Apoptosis - fly	K05770;K05770;K05770;K05770	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031090//organelle membrane	GO:0005515//protein binding;GO:0015485//cholesterol binding	GO:0032367//intracellular cholesterol transport;GO:0034389//lipid droplet organization;GO:0043353//enucleate erythrocyte differentiation;GO:0098739//import across plasma membrane;GO:0140484//5-aminolevulinic acid import across plasma membrane	--
ENSG00000112214	0	0	0	0.049	0.03	0	0	0	0	3	1	0	FHL5	four and a half LIM domains 5 [Source:HGNC Symbol;Acc:HGNC:17371]	-	-	-	-	GO:0005634//nucleus;GO:0030018//Z disc	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000112218	3.006	2.958	3.282	2.247	2.219	3.009	372	368	300	206	232	271	GPR63	G protein-coupled receptor 63 [Source:HGNC Symbol;Acc:HGNC:13302]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008150//biological_process	--
ENSG00000112232	1.408	1.519	1.205	0.752	0.784	1.024	68	74	43	27	32	36	KHDRBS2	"KH RNA binding domain containing, signal transduction associated 2 [Source:HGNC Symbol;Acc:HGNC:18114]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding;GO:0017124//SH3 domain binding;GO:0042169//SH2 domain binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000112234	5.891	4.605	5.186	4.225	4.78	4.771	572	490	361	292	398	326	FBXL4	F-box and leucine rich repeat protein 4 [Source:HGNC Symbol;Acc:HGNC:13601]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000112237	21.016	19.557	19.309	16.738	17.731	21.626	805	719	554	499	543	584	CCNC	cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0042802//identical protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045023//G0 to G1 transition;GO:0045746//negative regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity	--
ENSG00000112238	0	0	0	0	0	0	0	0	0	0	0	0	PRDM13	PR/SET domain 13 [Source:HGNC Symbol;Acc:HGNC:13998]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0016571//histone methylation;GO:0022008//neurogenesis;GO:0032259//methylation	zf-C2H2
ENSG00000112242	3.457	3.383	3.035	2.436	2.753	3.104	338	324	212	176	226	217	E2F3	E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05226//Gastric cancer;ko04110//Cell cycle;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05219//Bladder cancer	K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620;K06620	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070345//negative regulation of fat cell proliferation;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process"	E2F
ENSG00000112245	46.144	43.151	39.955	31.383	34.051	39.63	3395.09	3067.95	2146.98	1712.14	2114.97	1990.76	PTP4A1	protein tyrosine phosphatase 4A1 [Source:HGNC Symbol;Acc:HGNC:9634]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0016311//dephosphorylation;GO:0030335//positive regulation of cell migration;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000112246	0	0	0	0	0.007	0.017	0	0	0	0	1	1	SIM1	SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0001657//ureteric bud development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation"	bHLH
ENSG00000112249	6.739	4.631	3.889	2.617	4.228	3.328	984	727	458	303	479	373	ASCC3	activating signal cointegrator 1 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:18697]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0099053//activating signal cointegrator 1 complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043138//3'-5' DNA helicase activity	GO:0006281//DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0032508//DNA duplex unwinding;GO:0072344//rescue of stalled ribosome;GO:1990116//ribosome-associated ubiquitin-dependent protein catabolic process	--
ENSG00000112273	0	0	0	0	0	0	0	0	0	0	0	0	HDGFL1	HDGF like 1 [Source:HGNC Symbol;Acc:HGNC:21095]	-	-	-	-	GO:0005634//nucleus	GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000112276	2.987	2.469	2.818	2.279	2.969	3.996	289	230	201	167	212	248	BVES	blood vessel epicardial substance [Source:HGNC Symbol;Acc:HGNC:1152]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21108	GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0031253//cell projection membrane;GO:0042383//sarcolemma	GO:0000166//nucleotide binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030552//cAMP binding	GO:0001921//positive regulation of receptor recycling;GO:0002027//regulation of heart rate;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002931//response to ischemia;GO:0007155//cell adhesion;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0008360//regulation of cell shape;GO:0016192//vesicle-mediated transport;GO:0034446//substrate adhesion-dependent cell spreading;GO:0040017//positive regulation of locomotion;GO:0042391//regulation of membrane potential;GO:0043087//regulation of GTPase activity;GO:0048278//vesicle docking;GO:0051146//striated muscle cell differentiation;GO:0060931//sinoatrial node cell development;GO:0060973//cell migration involved in heart development;GO:0090136//epithelial cell-cell adhesion;GO:2001135//regulation of endocytic recycling	--
ENSG00000112280	17.286	18.725	17.63	12.402	13.68	11.051	1090	1182	821	579	729	510	COL9A1	collagen type IX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2217]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K08131;K08131;K08131;K08131;K08131	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005594//collagen type IX trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046872//metal ion binding	GO:0009887//animal organ morphogenesis;GO:0030198//extracellular matrix organization	--
ENSG00000112282	9.538	8.509	8.631	7.212	8.132	8.207	986	912	656	576	710	629	MED23	mediator complex subunit 23 [Source:HGNC Symbol;Acc:HGNC:2372]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000112290	9.359	8.653	7.737	10.81	7.934	12.395	481	421	271	371	353	415	WASF1	WASP family member 1 [Source:HGNC Symbol;Acc:HGNC:12732]	Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Immune system;Cancer: overview;Infectious disease: bacterial;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko05100//Bacterial invasion of epithelial cells;ko04520//Adherens junction	K05753;K05753;K05753;K05753;K05753;K05753;K05753	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031209//SCAR complex;GO:0032839//dendrite cytoplasm;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0098794//postsynapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0051018//protein kinase A binding;GO:0071933//Arp2/3 complex binding	GO:0006898//receptor-mediated endocytosis;GO:0016601//Rac protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0065003//protein-containing complex assembly;GO:0070584//mitochondrion morphogenesis;GO:0072673//lamellipodium morphogenesis;GO:0097484//dendrite extension;GO:0098885//modification of postsynaptic actin cytoskeleton;GO:0098939//dendritic transport of mitochondrion;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000112293	0.4	0.44	0.474	0.576	0.532	0.424	48	53.17	42.07	51.21	54	37.06	GPLD1	glycosylphosphatidylinositol specific phospholipase D1 [Source:HGNC Symbol;Acc:HGNC:4459]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K01127;K01127	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004621//glycosylphosphatidylinositol phospholipase D activity;GO:0004630//phospholipase D activity;GO:0016787//hydrolase activity;GO:0017080//sodium channel regulator activity	GO:0001503//ossification;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002062//chondrocyte differentiation;GO:0002430//complement receptor mediated signaling pathway;GO:0006501//C-terminal protein lipidation;GO:0006507//GPI anchor release;GO:0006629//lipid metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0009749//response to glucose;GO:0010595//positive regulation of endothelial cell migration;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010897//negative regulation of triglyceride catabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0032869//cellular response to insulin stimulus;GO:0035701//hematopoietic stem cell migration;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0043065//positive regulation of apoptotic process;GO:0046470//phosphatidylcholine metabolic process;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051047//positive regulation of secretion;GO:0070633//transepithelial transport;GO:0071277//cellular response to calcium ion;GO:0071397//cellular response to cholesterol;GO:0071401//cellular response to triglyceride;GO:0071466//cellular response to xenobiotic stimulus;GO:0071467//cellular response to pH;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:1900076//regulation of cellular response to insulin stimulus	--
ENSG00000112294	5.679	5.359	5.916	7.346	6.404	5.917	543	518	416	533	536	421	ALDH5A1	aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism;ko00650//Butanoate metabolism"	K00139;K00139;K00139	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0004777//succinate-semialdehyde dehydrogenase (NAD+) activity;GO:0009013//succinate-semialdehyde dehydrogenase [NAD(P)+] activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding"	GO:0006105//succinate metabolic process;GO:0006536//glutamate metabolic process;GO:0007417//central nervous system development;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009450//gamma-aminobutyric acid catabolic process;GO:0009791//post-embryonic development;GO:0042135//neurotransmitter catabolic process	--
ENSG00000112297	18.611	17.704	18.546	12.905	12.768	10.069	3753.24	3640.44	2814.6	1637.73	2159.49	1525.61	CRYBG1	crystallin beta-gamma domain containing 1 [Source:HGNC Symbol;Acc:HGNC:356]	-	-	-	-	-	GO:0030246//carbohydrate binding	-	--
ENSG00000112299	0	0	0	0	0	0	0	0	0	0	0	0	VNN1	vanin 1 [Source:HGNC Symbol;Acc:HGNC:12705]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K08069;K08069	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane	"GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0017159//pantetheine hydrolase activity"	GO:0002526//acute inflammatory response;GO:0002544//chronic inflammatory response;GO:0006807//nitrogen compound metabolic process;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0015939//pantothenate metabolic process;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0045087//innate immune response;GO:0098609//cell-cell adhesion;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000112303	0	0	0	0.04	0	0	0	0	0	1	0	0	VNN2	vanin 2 [Source:HGNC Symbol;Acc:HGNC:12706]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K08069;K08069	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0110165//cellular anatomical entity	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0017159//pantetheine hydrolase activity"	GO:0006807//nitrogen compound metabolic process;GO:0015939//pantothenate metabolic process	--
ENSG00000112304	4.822	4.147	4.136	2.86	3.11	3.52	406	352	257	180	221	218	ACOT13	acyl-CoA thioesterase 13 [Source:HGNC Symbol;Acc:HGNC:20999]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047617//acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0051289//protein homotetramerization;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000112305	17.771	15.25	15.478	13.631	14.542	16.74	988.66	868.99	640.45	539.77	666.98	684.53	SMAP1	small ArfGAP 1 [Source:HGNC Symbol;Acc:HGNC:19651]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12486	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030276//clathrin binding;GO:0046872//metal ion binding	GO:0045648//positive regulation of erythrocyte differentiation;GO:0050790//regulation of catalytic activity;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000112306	293.102	281.877	290.698	323.102	269.441	255.426	3058	2956	2240	2497	2375	1939	RPS12	ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10385]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02951;K02951	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000112308	35.996	33.504	30.134	27.989	29.383	28.615	1683	1517	1065	902	1094	1041	C6orf62	chromosome 6 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:20998]	-	-	-	-	-	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000112309	0.097	0.084	0.057	0.053	0.066	0.095	12.34	11.01	4.55	4.23	6.02	7.47	B3GAT2	"beta-1,3-glucuronyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:922]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K10157;K10157	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0016051//carbohydrate biosynthetic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process	--
ENSG00000112312	5.155	4.352	4.725	5.213	4.923	4.201	103	98	76	83	92	76	GMNN	geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0017053//transcription repressor complex	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008156//negative regulation of DNA replication;GO:0009887//animal organ morphogenesis;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0035563//positive regulation of chromatin binding;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0065003//protein-containing complex assembly;GO:0071163//DNA replication preinitiation complex assembly;GO:2000104//negative regulation of DNA-dependent DNA replication"	--
ENSG00000112319	3.023	1.575	2.608	2.446	2.157	2.881	271	163	147	131	172	175	EYA4	EYA transcriptional coactivator and phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:3522]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007275//multicellular organism development;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0009653//anatomical structure morphogenesis;GO:0016576//histone dephosphorylation;GO:0030154//cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045739//positive regulation of DNA repair;GO:0048839//inner ear development;GO:0048856//anatomical structure development;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000112320	3.663	3.962	3.754	3.555	3.786	3.809	473	509	358	340	413	353	SOBP	sine oculis binding protein homolog [Source:HGNC Symbol;Acc:HGNC:29256]	-	-	-	-	GO:0005634//nucleus	GO:0032184//SUMO polymer binding;GO:0046872//metal ion binding	GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0042472//inner ear morphogenesis;GO:0048513//animal organ development;GO:0050890//cognition;GO:0090102//cochlea development	--
ENSG00000112333	0.699	0.902	0.684	0.622	0.792	0.798	47	61	34	31	45	35	NR2E1	nuclear receptor subfamily 2 group E member 1 [Source:HGNC Symbol;Acc:HGNC:7973]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K08545	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001662//behavioral fear response;GO:0002118//aggressive behavior;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007601//visual perception;GO:0008284//positive regulation of cell population proliferation;GO:0008347//glial cell migration;GO:0021542//dentate gyrus development;GO:0021764//amygdala development;GO:0021772//olfactory bulb development;GO:0021819//layer formation in cerebral cortex;GO:0021872//forebrain generation of neurons;GO:0021895//cerebral cortex neuron differentiation;GO:0021960//anterior commissure morphogenesis;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030522//intracellular receptor signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0035176//social behavior;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0045165//cell fate commitment;GO:0045665//negative regulation of neuron differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045787//positive regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048712//negative regulation of astrocyte differentiation;GO:0048814//regulation of dendrite morphogenesis;GO:0048856//anatomical structure development;GO:0051128//regulation of cellular component organization;GO:0060041//retina development in camera-type eye;GO:0060164//regulation of timing of neuron differentiation;GO:0060291//long-term synaptic potentiation;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:2000178//negative regulation of neural precursor cell proliferation;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000648//positive regulation of stem cell proliferation"	RXR-like
ENSG00000112335	93.341	91.406	91.858	87.927	86.299	92.256	2919	2823	2089	2033	2262	2085	SNX3	sorting nexin 3 [Source:HGNC Symbol;Acc:HGNC:11174]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17918	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0030904//retromer complex;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032009//early phagosome;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0019903//protein phosphatase binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1901981//phosphatidylinositol phosphate binding;GO:1905394//retromer complex binding"	GO:0009617//response to bacterium;GO:0010324//membrane invagination;GO:0010976//positive regulation of neuron projection development;GO:0015031//protein transport;GO:0022615//protein to membrane docking;GO:0030111//regulation of Wnt signaling pathway;GO:0032456//endocytic recycling;GO:0034499//late endosome to Golgi transport;GO:0042177//negative regulation of protein catabolic process;GO:0046597//negative regulation of viral entry into host cell;GO:0050765//negative regulation of phagocytosis;GO:0051224//negative regulation of protein transport;GO:0070676//intralumenal vesicle formation;GO:2000642//negative regulation of early endosome to late endosome transport	--
ENSG00000112337	0	0	0	0	0	0	0	0	0	0	0	0	SLC17A2	solute carrier family 17 member 2 [Source:HGNC Symbol;Acc:HGNC:10930]	-	-	-	-	GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005436//sodium:phosphate symporter activity;GO:0015136//sialic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006796//phosphate-containing compound metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0015739//sialic acid transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000112339	32.665	25.454	30.837	21.124	24.295	24.866	1057	862	697	509	664	620	HBS1L	HBS1 like translational GTPase [Source:HGNC Symbol;Acc:HGNC:4834]	Genetic Information Processing;Human Diseases	Translation;Infectious disease: bacterial	ko03015//mRNA surveillance pathway;ko05134//Legionellosis	K14416;K14416	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0006417//regulation of translation;GO:0007165//signal transduction	--
ENSG00000112343	1.055	1.115	1.171	0.891	0.897	0.985	206	219	169	129	148	140	TRIM38	tripartite motif containing 38 [Source:HGNC Symbol;Acc:HGNC:10059]	-	-	-	-	GO:0005575//cellular_component;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032648//regulation of interferon-beta production;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045070//positive regulation of viral genome replication;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0046598//positive regulation of viral entry into host cell;GO:0050687//negative regulation of defense response to virus;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070936//protein K48-linked ubiquitination"	--
ENSG00000112357	7.45	6.845	9.95	7.692	7.99	8.409	201	208	197	151	193	177	PEX7	peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13341	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0005053//peroxisome matrix targeting signal-2 binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity	GO:0001764//neuron migration;GO:0001958//endochondral ossification;GO:0006625//protein targeting to peroxisome;GO:0006635//fatty acid beta-oxidation;GO:0007031//peroxisome organization;GO:0008611//ether lipid biosynthetic process;GO:0015031//protein transport;GO:0016558//protein import into peroxisome matrix	--
ENSG00000112365	2.463	1.936	1.887	1.408	2.075	1.951	281	222	159	119	200	162	ZBTB24	zinc finger and BTB domain containing 24 [Source:HGNC Symbol;Acc:HGNC:21143]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000112367	11.825	10.163	9.95	9.656	8.862	10.339	739	619	466	374	469	425	FIG4	FIG4 phosphoinositide 5-phosphatase [Source:HGNC Symbol;Acc:HGNC:16873]	Metabolism;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko00562//Inositol phosphate metabolism	K22913;K22913;K22913;K22913	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0106306//protein serine phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007033//vacuole organization;GO:0007626//locomotory behavior;GO:0010976//positive regulation of neuron projection development;GO:0031642//negative regulation of myelination;GO:0032288//myelin assembly;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043473//pigmentation;GO:0046488//phosphatidylinositol metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048666//neuron development	--
ENSG00000112378	15.837	15.493	15.503	14.465	15.537	15.231	1379	1356	997	933	1143	965	PERP	p53 apoptosis effector related to PMP22 [Source:HGNC Symbol;Acc:HGNC:17637]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10136	GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome	GO:0005515//protein binding	GO:0002934//desmosome organization;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway;GO:0034113//heterotypic cell-cell adhesion;GO:0045862//positive regulation of proteolysis;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0097186//amelogenesis;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0098609//cell-cell adhesion	--
ENSG00000112379	4.591	3.69	3.954	2.803	3.318	2.823	1415	1143	900	640	864	633	ARFGEF3	ARFGEF family member 3 [Source:HGNC Symbol;Acc:HGNC:21213]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000112394	24.149	25.458	23.762	14.071	13.989	22.465	1755	1558	1040	654	878.15	904	SLC16A10	solute carrier family 16 member 10 [Source:HGNC Symbol;Acc:HGNC:17027]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko04919//Thyroid hormone signaling pathway;ko04974//Protein digestion and absorption	K08187;K08187	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006590//thyroid hormone generation;GO:0006865//amino acid transport;GO:0015801//aromatic amino acid transport;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport;GO:0070460//thyroid-stimulating hormone secretion	--
ENSG00000112406	4.295	3.407	3.989	3.124	3.517	3.873	503	401	345	271	348	330	HECA	"hdc homolog, cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:21041]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003674//molecular_function	GO:0030323//respiratory tube development;GO:0045930//negative regulation of mitotic cell cycle	--
ENSG00000112414	1.101	0.905	0.759	1.205	1.339	1.711	157	129	79	129	160	165	ADGRG6	adhesion G protein-coupled receptor G6 [Source:HGNC Symbol;Acc:HGNC:13841]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0050840//extracellular matrix binding	GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0014037//Schwann cell differentiation;GO:0019933//cAMP-mediated signaling;GO:0022011//myelination in peripheral nervous system;GO:0042552//myelination;GO:0060347//heart trabecula formation	--
ENSG00000112419	13.735	8.359	10.381	7.72	7.859	8.824	1582	998	897	647	831	832	PHACTR2	phosphatase and actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:20956]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031092//platelet alpha granule membrane	GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0030036//actin cytoskeleton organization;GO:0043086//negative regulation of catalytic activity	--
ENSG00000112425	4.876	4.934	4.318	4.785	4.623	4.489	302	316	200	205	250	192	EPM2A	"EPM2A glucan phosphatase, laforin [Source:HGNC Symbol;Acc:HGNC:3413]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005844//polysome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0098554//cytoplasmic side of endoplasmic reticulum membrane;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane	GO:0004373//glycogen (starch) synthase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019203//carbohydrate phosphatase activity;GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity;GO:2001069//glycogen binding;GO:2001070//starch binding	GO:0000045//autophagosome assembly;GO:0001558//regulation of cell growth;GO:0001932//regulation of protein phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006470//protein dephosphorylation;GO:0006816//calcium ion transport;GO:0006914//autophagy;GO:0007005//mitochondrion organization;GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010923//negative regulation of phosphatase activity;GO:0014009//glial cell proliferation;GO:0015813//L-glutamate transmembrane transport;GO:0016055//Wnt signaling pathway;GO:0016239//positive regulation of macroautophagy;GO:0016311//dephosphorylation;GO:0031396//regulation of protein ubiquitination;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042306//regulation of protein import into nucleus;GO:0042325//regulation of phosphorylation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0045786//negative regulation of cell cycle;GO:0045859//regulation of protein kinase activity;GO:0046835//carbohydrate phosphorylation;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0046959//habituation;GO:0061136//regulation of proteasomal protein catabolic process;GO:1903076//regulation of protein localization to plasma membrane;GO:1904666//regulation of ubiquitin protein ligase activity;GO:2000465//regulation of glycogen (starch) synthase activity	--
ENSG00000112462	0	0	0	0	0	0	0	0	0	0	0	0	OR12D3	olfactory receptor family 12 subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:13963]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000112473	93.844	95.779	104.114	92.456	89.655	117.83	4425.03	4553	3604.14	3237	3594	4031.05	SLC39A7	solute carrier family 39 member 7 [Source:HGNC Symbol;Acc:HGNC:4927]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14713;K14713	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport	--
ENSG00000112486	0.058	0	0	0.113	0.033	0.022	3	0	0	3	1	1	CCR6	C-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:1607]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04181;K04181;K04181	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036126//sperm flagellum;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097524//sperm plasma membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0038023//signaling receptor activity	GO:0002407//dendritic cell chemotaxis;GO:0002523//leukocyte migration involved in inflammatory response;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0048290//isotype switching to IgA isotypes;GO:0060326//cell chemotaxis;GO:0060474//positive regulation of flagellated sperm motility involved in capacitation;GO:0070098//chemokine-mediated signaling pathway;GO:0072676//lymphocyte migration;GO:0072678//T cell migration;GO:0072679//thymocyte migration;GO:1904155//DN2 thymocyte differentiation;GO:1904156//DN3 thymocyte differentiation;GO:2000404//regulation of T cell migration;GO:2000510//positive regulation of dendritic cell chemotaxis	--
ENSG00000112494	0	0	0	0	0	0	0	0	0	0	0	0	UNC93A	unc-93 homolog A [Source:HGNC Symbol;Acc:HGNC:12570]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000112499	0	0	0	0.027	0.024	0.055	0	0	0	1	1	2	SLC22A2	solute carrier family 22 member 2 [Source:HGNC Symbol;Acc:HGNC:10966]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K08199	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0005275//amine transmembrane transporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0008504//monoamine transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015214//pyrimidine nucleoside transmembrane transporter activity;GO:0015220//choline transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006836//neurotransmitter transport;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007589//body fluid secretion;GO:0010628//positive regulation of gene expression;GO:0015695//organic cation transport;GO:0015837//amine transport;GO:0015871//choline transport;GO:0042908//xenobiotic transport;GO:0051610//serotonin uptake;GO:0051615//histamine uptake;GO:0051620//norepinephrine uptake;GO:0055085//transmembrane transport;GO:0072530//purine-containing compound transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:0090494//dopamine uptake;GO:0097638//L-arginine import across plasma membrane;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1901998//toxin transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903826//arginine transmembrane transport;GO:1990962//xenobiotic transport across blood-brain barrier	--
ENSG00000112511	15.244	14.794	16.646	16.153	19.259	23.04	672	642	506	520	686	627	PHF1	PHD finger protein 1 [Source:HGNC Symbol;Acc:HGNC:8919]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0035098//ESC/E(Z) complex;GO:0035861//site of double-strand break	GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990226//histone methyltransferase binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0031060//regulation of histone methylation;GO:0061086//negative regulation of histone H3-K27 methylation;GO:0061087//positive regulation of histone H3-K27 methylation"	--
ENSG00000112514	197.677	211.138	214.23	246.203	223.049	241.548	3430	3654	2741	3154	3281	3056	CUTA	cutA divalent cation tolerance homolog [Source:HGNC Symbol;Acc:HGNC:21101]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0008104//protein localization;GO:0010038//response to metal ion	--
ENSG00000112530	3.649	3	3.399	3.128	1.49	6.19	115	96	79	74	40	58	PACRG	parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0097225//sperm midpiece	GO:0001664//G protein-coupled receptor binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding	GO:0007286//spermatid development;GO:0034613//cellular protein localization;GO:0034620//cellular response to unfolded protein;GO:0060548//negative regulation of cell death	--
ENSG00000112531	73.614	59.885	57.15	50.651	58.521	57.648	4772	3645	2891	2315	2747	2767	QKI	"QKI, KH domain containing RNA binding [Source:HGNC Symbol;Acc:HGNC:21100]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045202//synapse	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding	"GO:0001570//vasculogenesis;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0007286//spermatid development;GO:0008366//axon ensheathment;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0042552//myelination;GO:0042692//muscle cell differentiation;GO:0042759//long-chain fatty acid biosynthetic process;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0051028//mRNA transport"	--
ENSG00000112539	0.185	0.553	0.107	0.143	0.188	0.073	7	21	3	4	6	2	C6orf118	chromosome 6 open reading frame 118 [Source:HGNC Symbol;Acc:HGNC:21233]	-	-	-	-	-	-	-	--
ENSG00000112541	0.041	0.062	0.101	0.008	0.049	0.056	5	10	4	1	7	5	PDE10A	phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]	Metabolism;Environmental Information Processing;Metabolism;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Substance dependence	ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko05032//Morphine addiction	K18438;K18438;K18438;K18438	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0046069//cGMP catabolic process	--
ENSG00000112559	18.242	17.501	17.535	18.534	19.047	19.149	458	403	337	374	433	325	MDFI	MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140416//transcription regulator inhibitor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0009950//dorsal/ventral axis specification;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043392//negative regulation of DNA binding;GO:0048704//embryonic skeletal system morphogenesis;GO:0060707//trophoblast giant cell differentiation	--
ENSG00000112561	11.722	12.154	12.344	14.353	13.779	13.798	560	589	445	519	561	494	TFEB	transcription factor EB [Source:HGNC Symbol;Acc:HGNC:11753]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K15590	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001892//embryonic placenta development;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006914//autophagy;GO:0006959//humoral immune response;GO:0007040//lysosome organization;GO:0009267//cellular response to starvation;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0032418//lysosome localization;GO:0034198//cellular response to amino acid starvation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000112562	282.106	316.757	214.349	105.994	150.374	87.637	17675	20045	9912	4963	8030	4079	SMOC2	SPARC related modular calcium binding 2 [Source:HGNC Symbol;Acc:HGNC:20323]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0071944//cell periphery	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0010595//positive regulation of endothelial cell migration;GO:0030198//extracellular matrix organization;GO:0035470//positive regulation of vascular wound healing;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0045931//positive regulation of mitotic cell cycle;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:2000573//positive regulation of DNA biosynthetic process;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000112576	10.526	10.464	10.66	12.489	12.475	11.373	438	428	323	371	426	337	CCND3	cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Signal transduction;Signal transduction;Cell growth and death;Signal transduction;Infectious disease: viral;Cell growth and death;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05162//Measles;ko04110//Cell cycle;ko04115//p53 signaling pathway	K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152;K10152	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0097130//cyclin D3-CDK4 complex	GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001934//positive regulation of protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0042098//T cell proliferation;GO:0042127//regulation of cell population proliferation;GO:0044772//mitotic cell cycle phase transition;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0046626//regulation of insulin receptor signaling pathway;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000112578	6.934	6.784	9.144	7.615	6.909	6.942	247	243	237	201	208	180	BYSL	bystin like [Source:HGNC Symbol;Acc:HGNC:1157]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030688//preribosome, small subunit precursor;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0045177//apical part of cell"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0001701//in utero embryonic development;GO:0001825//blastocyst formation;GO:0001829//trophectodermal cell differentiation;GO:0006364//rRNA processing;GO:0008283//cell population proliferation;GO:0042254//ribosome biogenesis;GO:1904749//regulation of protein localization to nucleolus"	--
ENSG00000112584	11.694	11.004	11.677	10.184	11.008	9.708	959	923	725	650	768	584	FAM120B	family with sequence similarity 120B [Source:HGNC Symbol;Acc:HGNC:21109]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0045444//fat cell differentiation	--
ENSG00000112592	5.574	5.633	5.849	4.88	5.797	4.837	193	172	140	121	155	119	TBP	TATA-box binding protein [Source:HGNC Symbol;Acc:HGNC:11588]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Transcription	ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko03022//Basal transcription factors	K03120;K03120;K03120;K03120;K03120;K03120	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0045120//pronucleus;GO:0097550//transcription preinitiation complex	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0001093//TFIIB-class transcription factor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0019899//enzyme binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140223//general transcription initiation factor activity;GO:0140297//DNA-binding transcription factor binding	"GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006383//transcription by RNA polymerase III;GO:0006468//protein phosphorylation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000112599	0.34	0.232	0.23	0.459	0.226	0.146	16	11	8	16	9	5	GUCA1B	guanylate cyclase activator 1B [Source:HGNC Symbol;Acc:HGNC:4679]	Organismal Systems	Sensory system	ko04744//Phototransduction	K08328	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042995//cell projection;GO:0097381//photoreceptor disc membrane;GO:0120199//cone photoreceptor outer segment	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0046872//metal ion binding	GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007267//cell-cell signaling;GO:0007589//body fluid secretion;GO:0007601//visual perception;GO:0031282//regulation of guanylate cyclase activity;GO:0031284//positive regulation of guanylate cyclase activity;GO:0050896//response to stimulus	--
ENSG00000112619	0.048	0.032	0	0	0.019	0	3	2	0	0	1	0	PRPH2	peripherin 2 [Source:HGNC Symbol;Acc:HGNC:9942]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0009645//response to low light intensity stimulus;GO:0035845//photoreceptor cell outer segment organization;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization;GO:0060041//retina development in camera-type eye	--
ENSG00000112624	5.555	5.135	4.749	4.515	5.126	5.053	749	696	473	451	584	496	BICRAL	BICRA like chromatin remodeling complex associated protein [Source:HGNC Symbol;Acc:HGNC:21111]	-	-	-	-	GO:0000785//chromatin;GO:0016514//SWI/SNF complex;GO:0140288//GBAF complex	GO:0005515//protein binding	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000112640	22.927	23.721	26.127	25.92	24.468	22.987	1216.49	1307.57	1047.77	1060.99	1134.73	864.26	PPP2R5D	protein phosphatase 2 regulatory subunit B'delta [Source:HGNC Symbol;Acc:HGNC:9312]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11584;K11584;K11584;K11584;K11584;K11584;K11584;K11584	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0035307//positive regulation of protein dephosphorylation;GO:0050790//regulation of catalytic activity	--
ENSG00000112651	13.953	12.347	15.516	18.873	16.575	11.51	270	255	230	267	252	163.1	MRPL2	mitochondrial ribosomal protein L2 [Source:HGNC Symbol;Acc:HGNC:14056]	Genetic Information Processing	Translation	ko03010//Ribosome	K02886	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000112655	37.445	39.514	34.381	31.991	36.561	33.498	3134	3336	2170	1970	2524	2042	PTK7	protein tyrosine kinase 7 (inactive) [Source:HGNC Symbol;Acc:HGNC:9618]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	"GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0050839//cell adhesion molecule binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	GO:0001736//establishment of planar polarity;GO:0001822//kidney development;GO:0001843//neural tube closure;GO:0003281//ventricular septum development;GO:0003401//axis elongation;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0007507//heart development;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0042060//wound healing;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0060026//convergent extension;GO:0060484//lung-associated mesenchyme development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060976//coronary vasculature development;GO:0071300//cellular response to retinoic acid;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000112658	8.74	9.704	9.535	10.214	11.869	9.898	767	856	618	664	880	632	SRF	serum response factor [Source:HGNC Symbol;Acc:HGNC:11291]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction	ko04010//MAPK signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04022//cGMP-PKG signaling pathway	K04378;K04378;K04378;K04378	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0010736//serum response element binding;GO:0031490//chromatin DNA binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070878//primary miRNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001569//branching involved in blood vessel morphogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0001764//neuron migration;GO:0001829//trophectodermal cell differentiation;GO:0001947//heart looping;GO:0002011//morphogenesis of an epithelial sheet;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002521//leukocyte differentiation;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007015//actin filament organization;GO:0007160//cell-matrix adhesion;GO:0007369//gastrulation;GO:0007507//heart development;GO:0007616//long-term memory;GO:0008285//negative regulation of cell population proliferation;GO:0008306//associative learning;GO:0009636//response to toxic substance;GO:0009725//response to hormone;GO:0010669//epithelial structure maintenance;GO:0010735//positive regulation of transcription via serum response element binding;GO:0021766//hippocampus development;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0030036//actin cytoskeleton organization;GO:0030038//contractile actin filament bundle assembly;GO:0030155//regulation of cell adhesion;GO:0030168//platelet activation;GO:0030220//platelet formation;GO:0030336//negative regulation of cell migration;GO:0030878//thyroid gland development;GO:0030900//forebrain development;GO:0031175//neuron projection development;GO:0033561//regulation of water loss via skin;GO:0034097//response to cytokine;GO:0035855//megakaryocyte development;GO:0035912//dorsal aorta morphogenesis;GO:0043149//stress fiber assembly;GO:0043589//skin morphogenesis;GO:0045059//positive thymic T cell selection;GO:0045214//sarcomere organization;GO:0045597//positive regulation of cell differentiation;GO:0045773//positive regulation of axon extension;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045987//positive regulation of smooth muscle contraction;GO:0046016//positive regulation of transcription by glucose;GO:0046716//muscle cell cellular homeostasis;GO:0048513//animal organ development;GO:0048538//thymus development;GO:0048589//developmental growth;GO:0048666//neuron development;GO:0048821//erythrocyte development;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051150//regulation of smooth muscle cell differentiation;GO:0051491//positive regulation of filopodium assembly;GO:0055003//cardiac myofibril assembly;GO:0060055//angiogenesis involved in wound healing;GO:0060218//hematopoietic stem cell differentiation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060292//long-term synaptic depression;GO:0060324//face development;GO:0060347//heart trabecula formation;GO:0060425//lung morphogenesis;GO:0060532//bronchus cartilage development;GO:0060534//trachea cartilage development;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0061029//eyelid development in camera-type eye;GO:0061145//lung smooth muscle development;GO:0070830//bicellular tight junction assembly;GO:0071333//cellular response to glucose stimulus;GO:0090009//primitive streak formation;GO:0090136//epithelial cell-cell adhesion;GO:0090398//cellular senescence;GO:0098609//cell-cell adhesion;GO:1900222//negative regulation of amyloid-beta clearance;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	SRF
ENSG00000112659	5.953	5.576	6.988	6.503	6.977	7.173	958	902	791	735	899	840	CUL9	cullin 9 [Source:HGNC Symbol;Acc:HGNC:15982]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031461//cullin-RING ubiquitin ligase complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding	GO:0000226//microtubule cytoskeleton organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007088//regulation of mitotic nuclear division;GO:0016567//protein ubiquitination	--
ENSG00000112667	24.429	27.303	27.849	34.608	27.927	32.112	335	376	280	351	322	321	DNPH1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:21218]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0070694//deoxyribonucleoside 5'-monophosphate N-glycosidase activity"	GO:0006195//purine nucleotide catabolic process;GO:0008152//metabolic process;GO:0009116//nucleoside metabolic process;GO:0009117//nucleotide metabolic process;GO:0009159//deoxyribonucleoside monophosphate catabolic process;GO:0030307//positive regulation of cell growth;GO:0030855//epithelial cell differentiation	--
ENSG00000112679	12.473	11.531	11.3	9.605	10.254	10.253	519	506	396	319	394	328	DUSP22	dual specificity phosphatase 22 [Source:HGNC Symbol;Acc:HGNC:16077]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031941//filamentous actin;GO:0061851//leading edge of lamellipodium	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity;GO:1990782//protein tyrosine kinase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002710//negative regulation of T cell mediated immunity;GO:0006470//protein dephosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016311//dephosphorylation;GO:0030336//negative regulation of cell migration;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042127//regulation of cell population proliferation;GO:0046330//positive regulation of JNK cascade;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0051895//negative regulation of focal adhesion assembly;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1903996//negative regulation of non-membrane spanning protein tyrosine kinase activity	--
ENSG00000112685	11.922	9.921	10.005	9.592	8.926	10.052	1073	909	683	645	697	676	EXOC2	exocyst complex component 2 [Source:HGNC Symbol;Acc:HGNC:24968]	Human Diseases;Environmental Information Processing	Infectious disease: bacterial;Signal transduction	ko05132//Salmonella infection;ko04014//Ras signaling pathway	K17637;K17637	GO:0000145//exocyst;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0047485//protein N-terminus binding	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis;GO:2000535//regulation of entry of bacterium into host cell	--
ENSG00000112695	67.326	79.905	91.623	84.325	74.499	78.075	645	771	648	601	604	546	COX7A2	cytochrome c oxidase subunit 7A2 [Source:HGNC Symbol;Acc:HGNC:2288]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity	"GO:0002082//regulation of oxidative phosphorylation;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:0097250//mitochondrial respirasome assembly"	--
ENSG00000112697	56.299	41.977	51.402	41.357	45.341	56.234	4965	3770	3427	2725	3312	3533	TMEM30A	transmembrane protein 30A [Source:HGNC Symbol;Acc:HGNC:16667]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0005515//protein binding;GO:0015247//aminophospholipid flippase activity	GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0010976//positive regulation of neuron projection development;GO:0015914//phospholipid transport;GO:0015917//aminophospholipid transport;GO:0036010//protein localization to endosome;GO:0045332//phospholipid translocation;GO:0061092//positive regulation of phospholipid translocation;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0140331//aminophospholipid translocation	--
ENSG00000112699	9.834	9.017	9.684	9.812	9.528	9.432	337	313	247	251	278	237	GMDS	"GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K01711;K01711;K01711	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008446//GDP-mannose 4,6-dehydratase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0070401//NADP+ binding"	GO:0007219//Notch signaling pathway;GO:0019673//GDP-mannose metabolic process;GO:0042351//'de novo' GDP-L-fucose biosynthetic process	--
ENSG00000112701	16.535	11.833	12.125	8.187	10.14	13.61	1105	823	622	425	547	678	SENP6	SUMO specific peptidase 6 [Source:HGNC Symbol;Acc:HGNC:20944]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070139//SUMO-specific endopeptidase activity	GO:0006508//proteolysis;GO:0016925//protein sumoylation;GO:0016926//protein desumoylation;GO:0070646//protein modification by small protein removal;GO:0090169//regulation of spindle assembly;GO:0090234//regulation of kinetochore assembly	--
ENSG00000112706	0	0.029	0	0.096	0.034	0.098	0	2	0	2	2	2	IMPG1	interphotoreceptor matrix proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:6055]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0033165//interphotoreceptor matrix;GO:0042995//cell projection;GO:0071944//cell periphery	GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding;GO:0008201//heparin binding;GO:0035374//chondroitin sulfate binding	GO:0007601//visual perception;GO:0030198//extracellular matrix organization	--
ENSG00000112715	87.35	80.184	70.217	75.197	88.073	68.824	5471	5228	3235	3579	4568	3077	VEGFA	vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Cancer: overview;Immune disease;Cardiovascular disease;Endocrine system;Signal transduction;Endocrine and metabolic disease;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko05323//Rheumatoid arthritis;ko05418//Fluid shear stress and atherosclerosis;ko04926//Relaxin signaling pathway;ko04066//HIF-1 signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05211//Renal cell carcinoma;ko04370//VEGF signaling pathway;ko05219//Bladder cancer	K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448;K05448	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0030141//secretory granule;GO:0031012//extracellular matrix;GO:0031093//platelet alpha granule lumen	GO:0001968//fibronectin binding;GO:0005125//cytokine activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0038191//neuropilin binding;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043183//vascular endothelial growth factor receptor 1 binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0048018//receptor ligand activity;GO:0050840//extracellular matrix binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002052//positive regulation of neuroblast proliferation;GO:0002092//positive regulation of receptor internalization;GO:0002575//basophil chemotaxis;GO:0002687//positive regulation of leukocyte migration;GO:0003007//heart morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003169//coronary vein morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007498//mesoderm development;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010749//regulation of nitric oxide mediated signal transduction;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030154//cell differentiation;GO:0030224//monocyte differentiation;GO:0030225//macrophage differentiation;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0030855//epithelial cell differentiation;GO:0031077//post-embryonic camera-type eye development;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031954//positive regulation of protein autophosphorylation;GO:0032147//activation of protein kinase activity;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035148//tube formation;GO:0035767//endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036303//lymph vessel morphogenesis;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0038190//VEGF-activated neuropilin signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0042462//eye photoreceptor cell development;GO:0043066//negative regulation of apoptotic process;GO:0043117//positive regulation of vascular permeability;GO:0043129//surfactant homeostasis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0045785//positive regulation of cell adhesion;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048469//cell maturation;GO:0048593//camera-type eye morphogenesis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0048844//artery morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0050927//positive regulation of positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051272//positive regulation of cellular component movement;GO:0051781//positive regulation of cell division;GO:0051894//positive regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0055013//cardiac muscle cell development;GO:0060319//primitive erythrocyte differentiation;GO:0060749//mammary gland alveolus development;GO:0060754//positive regulation of mast cell chemotaxis;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060982//coronary artery morphogenesis;GO:0061042//vascular wound healing;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071456//cellular response to hypoxia;GO:0071542//dopaminergic neuron differentiation;GO:0071679//commissural neuron axon guidance;GO:0090037//positive regulation of protein kinase C signaling;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090259//regulation of retinal ganglion cell axon guidance;GO:0097475//motor neuron migration;GO:0097533//cellular stress response to acid chemical;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:1900745//positive regulation of p38MAPK cascade;GO:1901165//positive regulation of trophoblast cell migration;GO:1901727//positive regulation of histone deacetylase activity;GO:1902336//positive regulation of retinal ganglion cell axon guidance;GO:1902966//positive regulation of protein localization to early endosome;GO:1903141//negative regulation of establishment of endothelial barrier;GO:1903392//negative regulation of adherens junction organization;GO:1903572//positive regulation of protein kinase D signaling;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903672//positive regulation of sprouting angiogenesis;GO:1905278//positive regulation of epithelial tube formation;GO:1905604//negative regulation of blood-brain barrier permeability;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000112739	8.21	5.943	6.273	4.223	4.795	6.371	1170	854	652	448	587	631	PRPF4B	pre-mRNA processing factor 4B [Source:HGNC Symbol;Acc:HGNC:17346]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0016310//phosphorylation;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000112742	0.671	0.939	0.352	0.461	0.649	0.247	33	43	16	21	24	8	TTK	TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K08866	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043515//kinetochore binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007051//spindle organization;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007093//mitotic cell cycle checkpoint signaling;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008284//positive regulation of cell population proliferation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016310//phosphorylation;GO:0016321//female meiosis chromosome segregation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033316//meiotic spindle assembly checkpoint signaling;GO:0034501//protein localization to kinetochore;GO:0034502//protein localization to chromosome;GO:0046777//protein autophosphorylation;GO:0051304//chromosome separation;GO:1903096//protein localization to meiotic spindle midzone	--
ENSG00000112759	22.355	22.513	19.362	18.491	20.053	18.006	977	1004	644	617	742	574	SLC29A1	solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003]	Human Diseases	Substance dependence	ko05034//Alcoholism	K15014	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005337//nucleoside transmembrane transporter activity;GO:0015211//purine nucleoside transmembrane transporter activity;GO:0015213//uridine transmembrane transporter activity;GO:0080122//AMP transmembrane transporter activity	GO:0001504//neurotransmitter uptake;GO:0006139//nucleobase-containing compound metabolic process;GO:0006836//neurotransmitter transport;GO:0007595//lactation;GO:0015858//nucleoside transport;GO:0015860//purine nucleoside transmembrane transport;GO:0015862//uridine transport;GO:0030431//sleep;GO:0032238//adenosine transport;GO:0060079//excitatory postsynaptic potential;GO:0071333//cellular response to glucose stimulus;GO:0071456//cellular response to hypoxia;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0080121//AMP transport;GO:0098810//neurotransmitter reuptake;GO:0150104//transport across blood-brain barrier;GO:1901642//nucleoside transmembrane transport	--
ENSG00000112761	0	0	0	0	0	0	0	0	0	0	0	0	CCN6	cellular communication network factor 6 [Source:HGNC Symbol;Acc:HGNC:12771]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008285//negative regulation of cell population proliferation;GO:0016525//negative regulation of angiogenesis;GO:0050793//regulation of developmental process;GO:0051881//regulation of mitochondrial membrane potential;GO:0060548//negative regulation of cell death;GO:1903426//regulation of reactive oxygen species biosynthetic process	--
ENSG00000112763	11.377	10.188	11.957	10.541	9.953	13.77	617.46	587	492	418	510	567	BTN2A1	butyrophilin subfamily 2 member A1 [Source:HGNC Symbol;Acc:HGNC:1136]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0006629//lipid metabolic process;GO:0050852//T cell receptor signaling pathway	--
ENSG00000112769	2.487	2.759	1.278	1.458	1.686	1.732	212	165	120	60	93	60	LAMA4	laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05143//African trypanosomiasis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06241;K06241;K06241;K06241;K06241;K06241;K06241;K06241;K06241	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016020//membrane;GO:0031594//neuromuscular junction;GO:0043083//synaptic cleft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0001568//blood vessel development;GO:0007155//cell adhesion;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0045995//regulation of embryonic development;GO:0050873//brown fat cell differentiation;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000112773	6.541	6.228	4.748	4.851	4.73	4.655	755	726	406	417	464	393	TENT5A	terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:1990817//RNA adenylyltransferase activity	GO:0009617//response to bacterium;GO:0030278//regulation of ossification;GO:0030501//positive regulation of bone mineralization;GO:0045669//positive regulation of osteoblast differentiation;GO:0048255//mRNA stabilization	--
ENSG00000112782	0.078	0.034	0.055	0.033	0.12	0.3	5	4	5	1	12	11	CLIC5	chloride intracellular channel 5 [Source:HGNC Symbol;Acc:HGNC:13517]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032421//stereocilium bundle;GO:0034707//chloride channel complex;GO:0070062//extracellular exosome	GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006749//glutathione metabolic process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007565//female pregnancy;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0050896//response to stimulus	--
ENSG00000112787	7.273	7.762	8.62	9.291	10.117	8.992	688	719	596	649	787	622	FBRSL1	fibrosin like 1 [Source:HGNC Symbol;Acc:HGNC:29308]	-	-	-	-	-	GO:0003723//RNA binding	-	--
ENSG00000112796	13.164	11.207	9.969	9.182	10.791	12.128	742	644	418	383	513	502	ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Source:HGNC Symbol;Acc:HGNC:13717]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000210//NAD+ diphosphatase activity;GO:0003824//catalytic activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0007154//cell communication	--
ENSG00000112799	0	0	0	0	0.133	0	0	0	0	0	2	0	LY86	lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response	--
ENSG00000112812	1.444	1.557	1.546	1.079	1.769	2.337	57	70	47	34	68	79	PRSS16	serine protease 16 [Source:HGNC Symbol;Acc:HGNC:9480]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0030163//protein catabolic process	--
ENSG00000112818	0	0	0	0	0	0	0	0	0	0	0	0	MEP1A	meprin A subunit alpha [Source:HGNC Symbol;Acc:HGNC:7015]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K01395	GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017090//meprin A complex;GO:0070062//extracellular exosome	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000112837	0.09	0.022	0.131	0.02	0	0.01	12	3	4	2	0	1	TBX18	T-box transcription factor 18 [Source:HGNC Symbol;Acc:HGNC:11595]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090571//RNA polymerase II transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001708//cell fate specification;GO:0001756//somitogenesis;GO:0003163//sinoatrial node development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016331//morphogenesis of embryonic epithelium;GO:0051145//smooth muscle cell differentiation;GO:0060829//negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0060930//sinoatrial node cell fate commitment;GO:0060931//sinoatrial node cell development;GO:0072189//ureter development;GO:0090103//cochlea morphogenesis;GO:0098907//regulation of SA node cell action potential"	T-box
ENSG00000112851	14.5	11.608	10.959	7.074	8.215	8.954	1750	1356	962	650	800	815	ERBIN	erbb2 interacting protein [Source:HGNC Symbol;Acc:HGNC:15842]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12796	GO:0005604//basement membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0031965//nuclear membrane;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005176//ErbB-2 class receptor binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0006605//protein targeting;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032495//response to muramyl dipeptide;GO:0032496//response to lipopolysaccharide;GO:0045104//intermediate filament cytoskeleton organization;GO:0045175//basal protein localization;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0070433//negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels	--
ENSG00000112852	20.175	21.267	21.355	17.2	19.241	19.808	1480.74	1603.7	1208.96	1013.45	1287.65	1008.54	PCDHB2	protocadherin beta 2 [Source:HGNC Symbol;Acc:HGNC:8687]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000112855	11.352	11.266	11.704	12.547	10.778	12.466	550	569	433	446	438	439	HARS2	"histidyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:4817]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01892	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004821//histidine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006427//histidyl-tRNA aminoacylation;GO:0034645//cellular macromolecule biosynthetic process	--
ENSG00000112874	7.91	6.547	6.62	5.345	6.063	6.842	508	422	333	274	300	321	NUDT12	nudix hydrolase 12 [Source:HGNC Symbol;Acc:HGNC:18826]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00760//Nicotinate and nicotinamide metabolism	K03426;K03426;K03426	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix	GO:0000210//NAD+ diphosphatase activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0046872//metal ion binding;GO:0110153//RNA NAD-cap (NMN-forming) hydrolase activity;GO:1990174//phosphodiesterase decapping endonuclease activity	"GO:0006402//mRNA catabolic process;GO:0006734//NADH metabolic process;GO:0006742//NADP catabolic process;GO:0019677//NAD catabolic process;GO:0032922//circadian regulation of gene expression;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0110155//NAD-cap decapping;GO:0110156//methylguanosine-cap decapping"	--
ENSG00000112877	0.795	1.176	0.8	0.77	0.844	0.756	39	58	29	28	35	27	CEP72	centrosomal protein 72 [Source:HGNC Symbol;Acc:HGNC:25547]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0007051//spindle organization;GO:0007099//centriole replication;GO:0033566//gamma-tubulin complex localization;GO:1904779//regulation of protein localization to centrosome	--
ENSG00000112893	65.714	53.191	54.509	48.618	52.658	61.427	8932	7267	5472	4895	6047	6075	MAN2A1	mannosidase alpha class 2A member 1 [Source:HGNC Symbol;Acc:HGNC:6824]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K01231;K01231;K01231	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0004572//mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity;GO:0015923//mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006517//protein deglycosylation;GO:0007005//mitochondrion organization;GO:0007033//vacuole organization;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008152//metabolic process;GO:0019082//viral protein processing;GO:0048286//lung alveolus development;GO:0050769//positive regulation of neurogenesis;GO:0060042//retina morphogenesis in camera-type eye	--
ENSG00000112902	5.462	4.909	4.553	3.692	3.949	4.013	1178	1175	786	650	787	667	SEMA5A	semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06841	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0035373//chondroitin sulfate proteoglycan binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0045499//chemorepellent activity;GO:0045545//syndecan binding	GO:0001755//neural crest cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0021536//diencephalon development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030836//positive regulation of actin filament depolymerization;GO:0045766//positive regulation of angiogenesis;GO:0048675//axon extension;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050918//positive chemotaxis;GO:0050919//negative chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0060326//cell chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1990256//signal clustering;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000112936	0.853	0.933	1.154	0.487	0.672	1.142	71	78	71	30	50	71	C7	complement C7 [Source:HGNC Symbol;Acc:HGNC:1346]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko04610//Complement and coagulation cascades	K03996;K03996;K03996;K03996	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response"	--
ENSG00000112941	3.878	4.66	4.429	2.941	4.117	3.953	293	354	250	197	290	269	TENT4A	terminal nucleotidyltransferase 4A [Source:HGNC Symbol;Acc:HGNC:16705]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K03514	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0031499//TRAMP complex;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0043221//SMC family protein binding;GO:0046872//metal ion binding;GO:0070568//guanylyltransferase activity	GO:0006302//double-strand break repair;GO:0006397//mRNA processing;GO:0007062//sister chromatid cohesion;GO:0007076//mitotic chromosome condensation;GO:0009410//response to xenobiotic stimulus;GO:0016070//RNA metabolic process;GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation;GO:0060212//negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0071076//RNA 3' uridylation;GO:1905870//positive regulation of 3'-UTR-mediated mRNA stabilization	--
ENSG00000112964	3.15	2.659	2.308	2.643	3.064	2.553	251	225	159	149	189	142	GHR	growth hormone receptor [Source:HGNC Symbol;Acc:HGNC:4263]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05080;K05080;K05080;K05080;K05080	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0070195//growth hormone receptor complex	GO:0004896//cytokine receptor activity;GO:0004903//growth hormone receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0019838//growth factor binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019955//cytokine binding;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0070064//proline-rich region binding	GO:0006897//endocytosis;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009725//response to hormone;GO:0009755//hormone-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0019530//taurine metabolic process;GO:0031623//receptor internalization;GO:0032094//response to food;GO:0032355//response to estradiol;GO:0032869//cellular response to insulin stimulus;GO:0032870//cellular response to hormone stimulus;GO:0034097//response to cytokine;GO:0040014//regulation of multicellular organism growth;GO:0040018//positive regulation of multicellular organism growth;GO:0042445//hormone metabolic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042976//activation of Janus kinase activity;GO:0043278//response to morphine;GO:0043406//positive regulation of MAP kinase activity;GO:0043434//response to peptide hormone;GO:0045597//positive regulation of cell differentiation;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046898//response to cycloheximide;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051384//response to glucocorticoid;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0060396//growth hormone receptor signaling pathway;GO:0060416//response to growth hormone;GO:0070555//response to interleukin-1;GO:1901215//negative regulation of neuron death	--
ENSG00000112972	27.932	27.609	28.922	31.136	29.624	35.424	2010	2017	1563	1680	1813	1882	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007]	Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Amino acid metabolism;Carbohydrate metabolism;Metabolism of terpenoids and polyketides	"ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism;ko00900//Terpenoid backbone biosynthesis"	K01641;K01641;K01641;K01641;K01641	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004421//hydroxymethylglutaryl-CoA synthase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042803//protein homodimerization activity	"GO:0006084//acetyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0010142//farnesyl diphosphate biosynthetic process, mevalonate pathway;GO:0016126//sterol biosynthetic process"	--
ENSG00000112977	106.312	110.209	112.026	118.123	111.724	103.696	5074	5280	3942	4176	4505	3601	DAP	death associated protein [Source:HGNC Symbol;Acc:HGNC:2672]	-	-	-	-	-	GO:0070513//death domain binding	"GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010507//negative regulation of autophagy;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034198//cellular response to amino acid starvation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0097190//apoptotic signaling pathway"	--
ENSG00000112981	4.829	4.725	4.269	2.748	3.259	4.224	121	119	79	51	69	77	NME5	NME/NM23 family member 5 [Source:HGNC Symbol;Acc:HGNC:7853]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005929//cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009116//nucleoside metabolic process;GO:0021591//ventricular system development;GO:0030154//cell differentiation;GO:0048515//spermatid differentiation;GO:0060271//cilium assembly;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000112983	13.567	14.309	14.64	10.025	11.244	10.081	745	854	644	441	545	458	BRD8	bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0035267//NuA4 histone acetyltransferase complex	GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0046966//thyroid hormone receptor binding	"GO:0006325//chromatin organization;GO:0007166//cell surface receptor signaling pathway;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0097067//cellular response to thyroid hormone stimulus;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000112984	0.779	1.069	1.16	1.051	0.722	1.021	50	69	55	50	38	47	KIF20A	kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0030496//midbody;GO:0045171//intercellular bridge	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity;GO:0019901//protein kinase binding	GO:0000281//mitotic cytokinesis;GO:0001578//microtubule bundle formation;GO:0007018//microtubule-based movement;GO:0015031//protein transport;GO:0032465//regulation of cytokinesis;GO:0061952//midbody abscission	--
ENSG00000112992	23.706	22.799	24.04	21.035	26.984	21.42	1938	1880	1334	1289	1521	1409.54	NNT	nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00323;K00323	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0003957//NAD(P)+ transhydrogenase (B-specific) activity;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0016491//oxidoreductase activity;GO:0050661//NADP binding;GO:0051287//NAD binding	GO:0006099//tricarboxylic acid cycle;GO:0006740//NADPH regeneration;GO:0072593//reactive oxygen species metabolic process;GO:1902600//proton transmembrane transport	--
ENSG00000112996	11.614	8.731	10.695	9.281	8.345	9.087	397	300	270	235	241	226	MRPS30	mitochondrial ribosomal protein S30 [Source:HGNC Symbol;Acc:HGNC:8769]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0006915//apoptotic process;GO:0032543//mitochondrial translation	--
ENSG00000113013	84.057	87.848	92.159	78.16	88.673	86.872	4984	4977	3874	3466	4091	3579	HSPA9	heat shock protein family A (Hsp70) member 9 [Source:HGNC Symbol;Acc:HGNC:5244]	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05152//Tuberculosis;ko03018//RNA degradation	K04043;K04043	GO:0001401//SAM complex;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005759//mitochondrial matrix;GO:0005925//focal adhesion;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular exosome;GO:0140275//MIB complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0006457//protein folding;GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0007007//inner mitochondrial membrane organization;GO:0016226//iron-sulfur cluster assembly;GO:0030218//erythrocyte differentiation;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0043066//negative regulation of apoptotic process;GO:0045646//regulation of erythrocyte differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0051085//chaperone cofactor-dependent protein refolding;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:1903707//negative regulation of hemopoiesis	--
ENSG00000113048	28.534	26.224	28.923	30.479	30.724	27.022	1554	1464	1189	1234	1437	1138	MRPS27	mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:14512]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0097177//mitochondrial ribosome binding	GO:0006417//regulation of translation;GO:0008283//cell population proliferation;GO:0032543//mitochondrial translation;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000113068	20.852	23.098	21.322	20.273	23.587	20.839	558	613	416	393	515	398	PFDN1	prefoldin subunit 1 [Source:HGNC Symbol;Acc:HGNC:8866]	-	-	-	-	GO:0005737//cytoplasm;GO:0016272//prefoldin complex	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0050821//protein stabilization;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000113070	1.472	1.546	1.578	0.524	0.581	0.393	72	76	57	19	24	14	HBEGF	heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Endocrine system;Endocrine system;Drug resistance: antineoplastic;Endocrine system;Signal transduction;Infectious disease: bacterial;Cancer: specific types	"ko05171//Coronavirus disease - COVID-19;ko05205//Proteoglycans in cancer;ko04915//Estrogen signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko01522//Endocrine resistance;ko04912//GnRH signaling pathway;ko04012//ErbB signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05219//Bladder cancer"	K08523;K08523;K08523;K08523;K08523;K08523;K08523;K08523;K08523	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	"GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007517//muscle organ development;GO:0008016//regulation of heart contraction;GO:0008284//positive regulation of cell population proliferation;GO:0016477//cell migration;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0035313//wound healing, spreading of epidermal cells;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051545//negative regulation of elastin biosynthetic process;GO:0051549//positive regulation of keratinocyte migration;GO:0051897//positive regulation of protein kinase B signaling;GO:0060326//cell chemotaxis;GO:0090303//positive regulation of wound healing"	--
ENSG00000113073	0.089	0	0	0	0.04	0.047	6	0	0	0	2	2	SLC4A9	solute carrier family 4 member 9 [Source:HGNC Symbol;Acc:HGNC:11035]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0045177//apical part of cell	GO:0005452//inorganic anion exchanger activity;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0035725//sodium ion transmembrane transport;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport	--
ENSG00000113083	41.926	38.001	28.954	25.226	26.356	24.024	3748	3197	1850	1582	1915	1461	LOX	lysyl oxidase [Source:HGNC Symbol;Acc:HGNC:6664]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix	"GO:0004720//protein-lysine 6-oxidase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0016491//oxidoreductase activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046872//metal ion binding"	GO:0001568//blood vessel development;GO:0001649//osteoblast differentiation;GO:0001932//regulation of protein phosphorylation;GO:0006464//cellular protein modification process;GO:0007507//heart development;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0010468//regulation of gene expression;GO:0016202//regulation of striated muscle tissue development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0018057//peptidyl-lysine oxidation;GO:0018158//protein oxidation;GO:0030199//collagen fibril organization;GO:0030282//bone mineralization;GO:0030324//lung development;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0035904//aorta development;GO:0035905//ascending aorta development;GO:0035906//descending aorta development;GO:0042060//wound healing;GO:0042981//regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0045652//regulation of megakaryocyte differentiation;GO:0046716//muscle cell cellular homeostasis;GO:0048251//elastic fiber assembly;GO:0048514//blood vessel morphogenesis;GO:0048545//response to steroid hormone;GO:0055001//muscle cell development;GO:0060326//cell chemotaxis;GO:0061448//connective tissue development;GO:0071310//cellular response to organic substance;GO:0071897//DNA biosynthetic process;GO:1900120//regulation of receptor binding;GO:1903010//regulation of bone development;GO:1990869//cellular response to chemokine;GO:2000586//regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000113088	0	0	0	0	0	0	0	0	0	0	0	0	GZMK	granzyme K [Source:HGNC Symbol;Acc:HGNC:4711]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000113100	0	0	0	0	0	0	0	0	0	0	0	0	CDH9	cadherin 9 [Source:HGNC Symbol;Acc:HGNC:1768]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000113108	2.276	2.819	2.587	1.691	3.146	2.703	95.05	109.25	72	54.16	110.11	74	APBB3	amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0050750//low-density lipoprotein particle receptor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0050714//positive regulation of protein secretion"	--
ENSG00000113119	3.986	2.81	2.082	3.741	3.391	4.736	84	94	54	68	86	92	TMCO6	transmembrane and coiled-coil domains 6 [Source:HGNC Symbol;Acc:HGNC:28814]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus	--
ENSG00000113140	805.87	877.218	742.756	817.567	816.923	750.454	46755	51215	30044	33375	39472	30127	SPARC	secreted protein acidic and cysteine rich [Source:HGNC Symbol;Acc:HGNC:11219]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031091//platelet alpha granule;GO:0031092//platelet alpha granule membrane;GO:0031093//platelet alpha granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0071682//endocytic vesicle lumen	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0001937//negative regulation of endothelial cell proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0022604//regulation of cell morphogenesis;GO:0048856//anatomical structure development	--
ENSG00000113141	36.973	34.47	31.934	23.75	27.147	27.408	1392	1354	881	638	830	763	IK	IK cytokine [Source:HGNC Symbol;Acc:HGNC:5958]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000278//mitotic cell cycle;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008380//RNA splicing;GO:0034501//protein localization to kinetochore"	--
ENSG00000113161	15.778	15.181	16.948	16.701	14.886	15.708	1386	1313	1062	1076	1108	1004	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006]	Metabolism;Environmental Information Processing;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Digestive system;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko04152//AMPK signaling pathway;ko04976//Bile secretion;ko00900//Terpenoid backbone biosynthesis	K00021;K00021;K00021;K00021	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004420//hydroxymethylglutaryl-CoA reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0050661//NADP binding;GO:0070402//NADPH binding;GO:0120225//coenzyme A binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0008542//visual learning;GO:0015936//coenzyme A metabolic process;GO:0016126//sterol biosynthetic process;GO:0042177//negative regulation of protein catabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0050709//negative regulation of protein secretion;GO:1900222//negative regulation of amyloid-beta clearance	--
ENSG00000113163	25.242	18.939	19.028	17.54	15.8	17.602	1933	1462	1023	793	1002	947	CERT1	ceramide transporter 1 [Source:HGNC Symbol;Acc:HGNC:2205]	-	-	-	-	GO:0005581//collagen trimer;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0097001//ceramide binding;GO:0120017//ceramide transfer activity;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0003007//heart morphogenesis;GO:0006672//ceramide metabolic process;GO:0006869//lipid transport;GO:0006936//muscle contraction;GO:0006955//immune response;GO:0007029//endoplasmic reticulum organization;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0034976//response to endoplasmic reticulum stress;GO:0035621//ER to Golgi ceramide transport;GO:0035627//ceramide transport;GO:0055088//lipid homeostasis;GO:0070584//mitochondrion morphogenesis;GO:0120009//intermembrane lipid transfer;GO:0120012//intermembrane sphingolipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000113194	19.251	20.363	20.507	17.748	18.449	18.87	1781	1884	1409	1223	1450	1248	FAF2	Fas associated factor family member 2 [Source:HGNC Symbol;Acc:HGNC:24666]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0035578//azurophil granule lumen	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035473//lipase binding;GO:0043130//ubiquitin binding;GO:0055102//lipase inhibitor activity	"GO:0006986//response to unfolded protein;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0034389//lipid droplet organization;GO:0043086//negative regulation of catalytic activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process"	--
ENSG00000113196	0	0	0	0	0	0	0	0	0	0	0	0	HAND1	heart and neural crest derivatives expressed 1 [Source:HGNC Symbol;Acc:HGNC:4807]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09071	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0001824//blastocyst development;GO:0001829//trophectodermal cell differentiation;GO:0001947//heart looping;GO:0003144//embryonic heart tube formation;GO:0003218//cardiac left ventricle formation;GO:0003219//cardiac right ventricle formation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0030154//cell differentiation;GO:0032502//developmental process;GO:0035050//embryonic heart tube development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0060485//mesenchyme development;GO:0060536//cartilage morphogenesis;GO:0060707//trophoblast giant cell differentiation;GO:0061371//determination of heart left/right asymmetry;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding"	bHLH
ENSG00000113205	0.318	0.559	0.468	0.399	0.409	0.218	22.11	39.11	24.04	20.55	24.02	11.05	PCDHB3	protocadherin beta 3 [Source:HGNC Symbol;Acc:HGNC:8688]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000113209	1.414	2.419	1.436	1.737	1.372	1.982	100	172	75	91	82	102	PCDHB5	protocadherin beta 5 [Source:HGNC Symbol;Acc:HGNC:8690]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000113211	0.092	0.055	0.121	0.05	0.035	0.051	5	3	6	2	2	2	PCDHB6	protocadherin beta 6 [Source:HGNC Symbol;Acc:HGNC:8691]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0009988//cell-cell recognition;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000113212	0	0.038	0	0	0.031	0.035	0	3	0	0	2	2	PCDHB7	protocadherin beta 7 [Source:HGNC Symbol;Acc:HGNC:8692]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000113231	0.499	0.428	0.767	0.912	0.461	0.412	26.53	39.92	22.66	50	37.23	27.79	PDE8B	phosphodiesterase 8B [Source:HGNC Symbol;Acc:HGNC:8794]	Metabolism;Human Diseases;Metabolism;Human Diseases;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Nucleotide metabolism;Substance dependence;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04927//Cortisol synthesis and secretion	K18437;K18437;K18437;K18437;K18437	GO:0005575//cellular_component;GO:0005829//cytosol	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction	--
ENSG00000113240	5.342	4.322	4.98	3.55	4.761	5.522	266	207	181	124	182	184	CLK4	CDC like kinase 4 [Source:HGNC Symbol;Acc:HGNC:13659]	Human Diseases	Infectious disease: bacterial	ko05134//Legionellosis	K23561	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043484//regulation of RNA splicing;GO:0046777//protein autophosphorylation	--
ENSG00000113248	0.804	1.16	0.74	0.803	0.805	0.876	66.2	96	45	49	56.04	52.48	PCDHB15	protocadherin beta 15 [Source:HGNC Symbol;Acc:HGNC:8686]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032391//photoreceptor connecting cilium	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000113249	0.074	0.056	0	0	0	0	2	2	0	0	0	0	HAVCR1	hepatitis A virus cellular receptor 1 [Source:HGNC Symbol;Acc:HGNC:17866]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium	GO:0001618//virus receptor activity;GO:0001786//phosphatidylserine binding;GO:0005515//protein binding	"GO:0006911//phagocytosis, engulfment;GO:0033005//positive regulation of mast cell activation;GO:0046718//viral entry into host cell"	--
ENSG00000113262	0	0	0	0	0	0	0	0	0	0	0	0	GRM6	glutamate metabotropic receptor 6 [Source:HGNC Symbol;Acc:HGNC:4598]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse	K04608;K04608;K04608	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0035841//new growing cell tip;GO:0042995//cell projection;GO:0045202//synapse	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0042803//protein homodimerization activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007601//visual perception;GO:0007626//locomotory behavior;GO:0009584//detection of visible light;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0050953//sensory perception of light stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060041//retina development in camera-type eye;GO:0090280//positive regulation of calcium ion import"	--
ENSG00000113263	0	0	0	0	0.038	0	0	0	0	0	3	0	ITK	IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171]	Organismal Systems;Organismal Systems;Organismal Systems	Immune system;Immune system;Immune system	ko04062//Chemokine signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway	K07363;K07363;K07363	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0001819//positive regulation of cytokine production;GO:0001865//NK T cell differentiation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007202//activation of phospholipase C activity;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042110//T cell activation;GO:0046629//gamma-delta T cell activation;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway	--
ENSG00000113269	63.015	59.983	67.614	63.623	62.551	67.295	2536	2429	2007	1885	2134	1977	RNF130	ring finger protein 130 [Source:HGNC Symbol;Acc:HGNC:18280]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0012501//programmed cell death;GO:0016567//protein ubiquitination	--
ENSG00000113272	4.002	5.138	4.679	3.971	4.213	4.547	219	285	149	176	213	189	THG1L	tRNA-histidine guanylyltransferase 1 like [Source:HGNC Symbol;Acc:HGNC:26053]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:1990234//transferase complex	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008193//tRNA guanylyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006400//tRNA modification;GO:0006979//response to oxidative stress;GO:0008033//tRNA processing;GO:0008053//mitochondrial fusion;GO:0050790//regulation of catalytic activity;GO:0051289//protein homotetramerization;GO:0099116//tRNA 5'-end processing;GO:1990046//stress-induced mitochondrial fusion	--
ENSG00000113273	13.263	12.792	12.046	11.728	12.892	14.004	1190	1190	822	788	1028	969	ARSB	arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01135;K01135;K01135	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005788//endoplasmic reticulum lumen;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003824//catalytic activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006914//autophagy;GO:0007040//lysosome organization;GO:0007041//lysosomal transport;GO:0007417//central nervous system development;GO:0007584//response to nutrient;GO:0009268//response to pH;GO:0010632//regulation of epithelial cell migration;GO:0010976//positive regulation of neuron projection development;GO:0043627//response to estrogen;GO:0051597//response to methylmercury;GO:0061580//colon epithelial cell migration	--
ENSG00000113282	24.565	23.942	20.896	17.462	18.436	21.809	1498	1480	951	823	1004	988	CLINT1	clathrin interactor 1 [Source:HGNC Symbol;Acc:HGNC:23186]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030125//clathrin vesicle coat;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0030276//clathrin binding;GO:0045296//cadherin binding	GO:0006897//endocytosis;GO:0016192//vesicle-mediated transport	--
ENSG00000113296	0.452	0.667	0.464	0.652	0.295	0.321	29	43	22	31	16	15	THBS4	thrombospondin 4 [Source:HGNC Symbol;Acc:HGNC:11788]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Transport and catabolism;Cellular community - eukaryotes;Signaling molecules and interaction;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko04510//Focal adhesion;ko04512//ECM-receptor interaction;ko05144//Malaria	K04659;K04659;K04659;K04659;K04659;K04659	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016529//sarcoplasmic reticulum;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0006986//response to unfolded protein;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0016525//negative regulation of angiogenesis;GO:0034103//regulation of tissue remodeling;GO:0034976//response to endoplasmic reticulum stress;GO:0048266//behavioral response to pain;GO:0048771//tissue remodeling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051451//myoblast migration;GO:0051781//positive regulation of cell division;GO:0071603//endothelial cell-cell adhesion;GO:0090023//positive regulation of neutrophil chemotaxis	--
ENSG00000113300	12.67	9.474	11.616	9.824	10.282	9.921	1241	1059	882	689	832	805	CNOT6	CCR4-NOT transcription complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:14099]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12603	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030014//CCR4-NOT complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004532//exoribonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030374//nuclear receptor coactivator activity;GO:0046872//metal ion binding	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006417//regulation of translation;GO:0008284//positive regulation of cell population proliferation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000113302	0	0	0	0	0	0	0	0	0	0	0	0	IL12B	interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: bacterial;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Infectious disease: parasitic;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic;Immune disease;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05164//Influenza A;ko05146//Amoebiasis;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko04658//Th1 and Th2 cell differentiation;ko05133//Pertussis;ko04622//RIG-I-like receptor signaling pathway;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko04940//Type I diabetes mellitus	K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425;K05425	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031906//late endosome lumen;GO:0043235//receptor complex;GO:0043514//interleukin-12 complex;GO:0070743//interleukin-23 complex	GO:0004896//cytokine receptor activity;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0019955//cytokine binding;GO:0042164//interleukin-12 alpha subunit binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045519//interleukin-23 receptor binding;GO:0046982//protein heterodimerization activity	GO:0001817//regulation of cytokine production;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002230//positive regulation of defense response to virus by host;GO:0002323//natural killer cell activation involved in immune response;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0008283//cell population proliferation;GO:0010033//response to organic substance;GO:0010224//response to UV-B;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0016477//cell migration;GO:0019221//cytokine-mediated signaling pathway;GO:0019233//sensory perception of pain;GO:0019953//sexual reproduction;GO:0030101//natural killer cell activation;GO:0032693//negative regulation of interleukin-10 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0032819//positive regulation of natural killer cell proliferation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0034105//positive regulation of tissue remodeling;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0042088//T-helper 1 type immune response;GO:0042093//T-helper cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042832//defense response to protozoan;GO:0043382//positive regulation of memory T cell differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045785//positive regulation of cell adhesion;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050709//negative regulation of protein secretion;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0051135//positive regulation of NK T cell activation;GO:0051142//positive regulation of NK T cell proliferation;GO:0051607//defense response to virus;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000330//positive regulation of T-helper 17 cell lineage commitment	--
ENSG00000113303	0	0	0	0	0	0	0	0	0	0	0	0	BTNL8	butyrophilin like 8 [Source:HGNC Symbol;Acc:HGNC:26131]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0050852//T cell receptor signaling pathway	--
ENSG00000113312	26.09	28.757	25.673	27.733	22.088	26.741	778	862	566	613	557	580	TTC1	tetratricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12391]	-	-	-	-	GO:0005778//peroxisomal membrane;GO:0005829//cytosol	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding	--
ENSG00000113318	5.103	4.118	4.152	3.004	3.384	2.463	430.27	354.68	248.19	186.44	229.73	155.36	MSH3	mutS homolog 3 [Source:HGNC Symbol;Acc:HGNC:7326]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Replication and repair	ko05200//Pathways in cancer;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko03430//Mismatch repair	K08736;K08736;K08736;K08736	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0032302//MutSbeta complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0030983//mismatched DNA binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0032142//single guanine insertion binding;GO:0032181//dinucleotide repeat insertion binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006312//mitotic recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043570//maintenance of DNA repeat elements;GO:0045910//negative regulation of DNA recombination;GO:0050896//response to stimulus;GO:0051096//positive regulation of helicase activity	--
ENSG00000113319	23.551	22.26	21.66	19.609	20.799	23.145	2978	2741	1989	1820	2202	1971	RASGRF2	Ras protein specific guanine nucleotide releasing factor 2 [Source:HGNC Symbol;Acc:HGNC:9876]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway	K12326;K12326	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0034976//response to endoplasmic reticulum stress;GO:0035023//regulation of Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0046578//regulation of Ras protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060291//long-term synaptic potentiation;GO:2000310//regulation of NMDA receptor activity	--
ENSG00000113327	0.025	0.104	0.043	0	0	0.034	1	2	2	0	0	1	GABRG2	gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05186;K05186;K05186;K05186;K05186	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902710//GABA receptor complex;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008503//benzodiazepine receptor activity;GO:0016917//GABA receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0009791//post-embryonic development;GO:0030534//adult behavior;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0071420//cellular response to histamine;GO:1902476//chloride transmembrane transport;GO:1904862//inhibitory synapse assembly"	--
ENSG00000113328	47.566	40.477	39.028	42.209	39.058	44.146	2378	2035	1441	1571	1668	1613	CCNG1	cyclin G1 [Source:HGNC Symbol;Acc:HGNC:1592]	Human Diseases;Cellular Processes	Cancer: overview;Cell growth and death	ko05206//MicroRNAs in cancer;ko04115//p53 signaling pathway	K10145;K10145	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006949//syncytium formation;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007420//brain development;GO:0010243//response to organonitrogen compound;GO:0043066//negative regulation of apoptotic process;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000113356	0.413	0.395	0.321	0.34	0.484	0.31	28	27	15	17	23	13	POLR3G	RNA polymerase III subunit G [Source:HGNC Symbol;Acc:HGNC:30075]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03024;K03024	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003682//chromatin binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0006359//regulation of transcription by RNA polymerase III;GO:0006383//transcription by RNA polymerase III;GO:0008283//cell population proliferation;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus	--
ENSG00000113360	16.82	17.567	15.202	14.859	14.331	14.612	1414	1358	966	864	992	869	DROSHA	drosha ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17904]	Human Diseases;Genetic Information Processing	Cancer: overview;Translation	ko05205//Proteoglycans in cancer;ko03008//Ribosome biogenesis in eukaryotes	K03685;K03685	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0070877//microprocessor complex	GO:0001530//lipopolysaccharide binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004525//ribonuclease III activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0017151//DEAD/H-box RNA helicase binding;GO:0042803//protein homodimerization activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0070412//R-SMAD binding;GO:0070878//primary miRNA binding	"GO:0006396//RNA processing;GO:0010468//regulation of gene expression;GO:0010586//miRNA metabolic process;GO:0010628//positive regulation of gene expression;GO:0016075//rRNA catabolic process;GO:0031047//gene silencing by RNA;GO:0031053//primary miRNA processing;GO:0031054//pre-miRNA processing;GO:0042254//ribosome biogenesis;GO:0045589//regulation of regulatory T cell differentiation;GO:0050727//regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:2000628//regulation of miRNA metabolic process"	--
ENSG00000113361	1.985	2.181	1.901	2.311	2.84	3.295	215	231	140	193	234	250	CDH6	cadherin 6 [Source:HGNC Symbol;Acc:HGNC:1765]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0030054//cell junction	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007219//Notch signaling pathway;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000113368	2.836	2.68	2.699	3.101	2.774	2.484	170	162	120	132	141	109	LMNB1	lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K07611	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005638//lamin filament;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031965//nuclear membrane	GO:0003690//double-stranded DNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0043274//phospholipase binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006998//nuclear envelope organization	--
ENSG00000113369	6.744	6.393	3.757	2.979	3.985	2.048	593	565	244	194	296	131	ARRDC3	arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0031699//beta-3 adrenergic receptor binding	GO:0001659//temperature homeostasis;GO:0015031//protein transport;GO:0031651//negative regulation of heat generation;GO:0043588//skin development;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0060613//fat pad development;GO:0071878//negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0090327//negative regulation of locomotion involved in locomotory behavior;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000113384	47.101	43.559	48.19	44.282	42.17	54.063	2612	2432	1973	1822	1979	2176	GOLPH3	golgi phosphoprotein 3 [Source:HGNC Symbol;Acc:HGNC:15452]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031985//Golgi cisterna;GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0070273//phosphatidylinositol-4-phosphate binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0009101//glycoprotein biosynthetic process;GO:0009306//protein secretion;GO:0010467//gene expression;GO:0010821//regulation of mitochondrion organization;GO:0015031//protein transport;GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0032008//positive regulation of TOR signaling;GO:0043001//Golgi to plasma membrane protein transport;GO:0043066//negative regulation of apoptotic process;GO:0045053//protein retention in Golgi apparatus;GO:0048194//Golgi vesicle budding;GO:0050714//positive regulation of protein secretion;GO:0050901//leukocyte tethering or rolling;GO:0060352//cell adhesion molecule production;GO:0072752//cellular response to rapamycin;GO:0090161//Golgi ribbon formation;GO:0090164//asymmetric Golgi ribbon formation"	--
ENSG00000113387	69.989	73.709	68.261	66.403	58.403	56.161	1733	1717	1195	1090	1243	1085	SUB1	SUB1 regulator of transcription [Source:HGNC Symbol;Acc:HGNC:19985]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0070062//extracellular exosome	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0001111//promoter clearance from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032508//DNA duplex unwinding;GO:0051053//negative regulation of DNA metabolic process;GO:0051260//protein homooligomerization;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060395//SMAD protein signal transduction"	PC4
ENSG00000113389	11.539	13.142	4.54	9.601	15.402	11.797	1390	1446	341	815	1422	984	NPR3	natriuretic peptide receptor 3 [Source:HGNC Symbol;Acc:HGNC:7945]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016941//natriuretic peptide receptor activity;GO:0017046//peptide hormone binding;GO:0031404//chloride ion binding;GO:0042277//peptide binding;GO:0042562//hormone binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0001501//skeletal system development;GO:0002158//osteoclast proliferation;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0030157//pancreatic juice secretion;GO:0033688//regulation of osteoblast proliferation;GO:0035810//positive regulation of urine volume;GO:0042311//vasodilation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000113391	10.446	9.067	6.668	7.293	6.713	8.017	788	726	421	402	453	470	FAM172A	family with sequence similarity 172 member A [Source:HGNC Symbol;Acc:HGNC:25365]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0035197//siRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0014032//neural crest cell development;GO:0031048//heterochromatin assembly by small RNA"	--
ENSG00000113396	8.427	8.833	6.002	4.674	6.432	5.036	496	497	258	202	306	215	SLC27A6	solute carrier family 27 member 6 [Source:HGNC Symbol;Acc:HGNC:11000]	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Endocrine system	ko04931//Insulin resistance;ko03320//PPAR signaling pathway	K08749;K08749	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0015245//fatty acid transmembrane transporter activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:1901480//oleate transmembrane transporter activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006869//lipid transport;GO:0015711//organic anion transport;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport	--
ENSG00000113407	37.656	32.276	30.744	26.405	26.35	49.838	2083	1798	1253	1084	1232	2003	TARS1	threonyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:11572]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01868	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004829//threonine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0042802//identical protein binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006435//threonyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation	--
ENSG00000113430	0	0.064	0	0	0	0	0	1	0	0	0	0	IRX4	iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0030182//neuron differentiation;GO:0048468//cell development;GO:0048561//establishment of animal organ orientation"	Homeobox
ENSG00000113441	3.353	3.453	2.934	2.044	2.48	2.474	844	734	475	381	472	453	LNPEP	leucyl and cystinyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:6656]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K01257	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031905//early endosome lumen;GO:0048471//perinuclear region of cytoplasm	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	"GO:0000209//protein polyubiquitination;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0008217//regulation of blood pressure;GO:0030163//protein catabolic process;GO:0043171//peptide catabolic process;GO:0060395//SMAD protein signal transduction;GO:0120163//negative regulation of cold-induced thermogenesis"	--
ENSG00000113448	2.814	1.927	1.474	2.377	2.471	1.408	280	245	128	116	129	114	PDE4D	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]	Metabolism;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction"	K13293;K13293;K13293;K13293;K13293	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0034704//calcium channel complex;GO:0048471//perinuclear region of cytoplasm	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030552//cAMP binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding;GO:0097110//scaffold protein binding;GO:1901363//heterocyclic compound binding"	GO:0002027//regulation of heart rate;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0010469//regulation of signaling receptor activity;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0019933//cAMP-mediated signaling;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0032754//positive regulation of interleukin-5 production;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0045822//negative regulation of heart contraction;GO:0050852//T cell receptor signaling pathway;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0061028//establishment of endothelial barrier;GO:0071320//cellular response to cAMP;GO:0071872//cellular response to epinephrine stimulus;GO:0071875//adrenergic receptor signaling pathway;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086024//adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1901898//negative regulation of relaxation of cardiac muscle	--
ENSG00000113456	12.496	13.181	13.851	8.366	9.476	11.624	633	603	492.06	346	417	397	RAD1	RAD1 checkpoint DNA exonuclease [Source:HGNC Symbol;Acc:HGNC:9806]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K02830	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0030896//checkpoint clamp complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003684//damaged DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0008853//exodeoxyribonuclease III activity;GO:0016787//hydrolase activity	GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0021762//substantia nigra development;GO:0051598//meiotic recombination checkpoint signaling;GO:0071479//cellular response to ionizing radiation;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000113460	6.97	6.12	7.916	5.236	5.559	6.539	230	203	192.94	128	155	157	BRIX1	biogenesis of ribosomes BRX1 [Source:HGNC Symbol;Acc:HGNC:24170]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000113492	0	0	0	0	0	0	0	0	0	0	0	0	AGXT2	alanine--glyoxylate aminotransferase 2 [Source:HGNC Symbol;Acc:HGNC:14412]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00260//Glycine, serine and threonine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K00827;K00827;K00827;K00827;K00827	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0008453//alanine-glyoxylate transaminase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0047305//(R)-3-amino-2-methylpropionate-pyruvate transaminase activity	"GO:0009436//glyoxylate catabolic process;GO:0019265//glycine biosynthetic process, by transamination of glyoxylate;GO:0019481//L-alanine catabolic process, by transamination;GO:0045429//positive regulation of nitric oxide biosynthetic process"	--
ENSG00000113494	5.787	3.888	2.264	0.843	1.183	0.967	1336	845	293	150	196	169	PRLR	prolactin receptor [Source:HGNC Symbol;Acc:HGNC:9446]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K05081;K05081;K05081;K05081;K05081	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031904//endosome lumen;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0004925//prolactin receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0019901//protein kinase binding;GO:0019955//cytokine binding;GO:0046872//metal ion binding	GO:0006694//steroid biosynthetic process;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007566//embryo implantation;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0019221//cytokine-mediated signaling pathway;GO:0030155//regulation of cell adhesion;GO:0030856//regulation of epithelial cell differentiation;GO:0038161//prolactin signaling pathway;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0042976//activation of Janus kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0060644//mammary gland epithelial cell differentiation;GO:0060736//prostate gland growth;GO:0060749//mammary gland alveolus development;GO:0061180//mammary gland epithelium development;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000113504	13.523	13.688	14.496	14.897	15.393	15.316	1417	1495	1177	1204	1406	1207	SLC12A7	solute carrier family 12 member 7 [Source:HGNC Symbol;Acc:HGNC:10915]	Organismal Systems	Excretory system	ko04966//Collecting duct acid secretion	K13627	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045202//synapse	GO:0008519//ammonium transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0007268//chemical synaptic transmission;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0140157//ammonium import across plasma membrane;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000113520	0	0	0	0	0	0	0	0	0	0	0	0	IL4	interleukin 4 [Source:HGNC Symbol;Acc:HGNC:6014]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Immune disease;Immune system;Immune system;Immune system;Immune disease;Immune disease;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko05321//Inflammatory bowel disease	K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430;K05430	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005136//interleukin-4 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001774//microglial cell activation;GO:0002227//innate immune response in mucosa;GO:0002230//positive regulation of defense response to virus by host;GO:0002674//negative regulation of acute inflammatory response;GO:0002677//negative regulation of chronic inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008203//cholesterol metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010633//negative regulation of epithelial cell migration;GO:0016239//positive regulation of macroautophagy;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0031296//B cell costimulation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0032736//positive regulation of interleukin-13 production;GO:0042092//type 2 immune response;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0042116//macrophage activation;GO:0042325//regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042976//activation of Janus kinase activity;GO:0043011//myeloid dendritic cell differentiation;GO:0043031//negative regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043306//positive regulation of mast cell degranulation;GO:0045064//T-helper 2 cell differentiation;GO:0045191//regulation of isotype switching;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045582//positive regulation of T cell differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050728//negative regulation of inflammatory response;GO:0050776//regulation of immune response;GO:0071677//positive regulation of mononuclear cell migration;GO:0097028//dendritic cell differentiation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0150076//neuroinflammatory response;GO:0150079//negative regulation of neuroinflammatory response;GO:1900223//positive regulation of amyloid-beta clearance;GO:1901741//positive regulation of myoblast fusion;GO:1901857//positive regulation of cellular respiration;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:1903845//negative regulation of cellular response to transforming growth factor beta stimulus;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000424//positive regulation of eosinophil chemotaxis;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2001171//positive regulation of ATP biosynthetic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000113522	4.776	4.208	2.753	2.851	2.791	3.371	527.83	382.46	178.22	170.07	251.96	185.52	RAD50	RAD50 double strand break repair protein [Source:HGNC Symbol;Acc:HGNC:9816]	Cellular Processes;Genetic Information Processing;Genetic Information Processing	Cell growth and death;Replication and repair;Replication and repair	ko04218//Cellular senescence;ko03440//Homologous recombination;ko03450//Non-homologous end-joining	K10866;K10866;K10866	"GO:0000781//chromosome, telomeric region;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0030870//Mre11 complex;GO:0035861//site of double-strand break;GO:0043231//intracellular membrane-bounded organelle;GO:0070533//BRCA1-C complex;GO:0098687//chromosomal region"	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003691//double-stranded telomeric DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0043047//single-stranded telomeric DNA binding;GO:0046872//metal ion binding;GO:0051880//G-quadruplex DNA binding	GO:0000019//regulation of mitotic recombination;GO:0000722//telomere maintenance via recombination;GO:0000723//telomere maintenance;GO:0000729//DNA double-strand break processing;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007004//telomere maintenance via telomerase;GO:0007049//cell cycle;GO:0007131//reciprocal meiotic recombination;GO:0031860//telomeric 3' overhang formation;GO:0031954//positive regulation of protein autophosphorylation;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0033674//positive regulation of kinase activity;GO:0035825//homologous recombination;GO:0044818//mitotic G2/M transition checkpoint;GO:0051276//chromosome organization;GO:0051321//meiotic cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0110025//DNA strand resection involved in replication fork processing;GO:1904354//negative regulation of telomere capping	--
ENSG00000113525	0	0	0	0	0	0	0	0	0	0	0	0	IL5	interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signaling molecules and interaction;Immune system;Signal transduction;Immune system;Immune disease;Immune system;Immune system;Immune disease;Immune disease;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko05321//Inflammatory bowel disease	K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428;K05428	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005137//interleukin-5 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0002639//positive regulation of immunoglobulin production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0045645//positive regulation of eosinophil differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0071803//positive regulation of podosome assembly"	--
ENSG00000113532	1.335	0.827	0.713	0.35	0.628	0.803	133	109	69	34	62	68	ST8SIA4	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10871]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033691//sialic acid binding"	GO:0001574//ganglioside biosynthetic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0007399//nervous system development;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation	--
ENSG00000113552	52.966	50.92	66.01	69.369	58.357	66.644	2008	1821	1625	1661	1681	1630	GNPDA1	glucosamine-6-phosphate deaminase 1 [Source:HGNC Symbol;Acc:HGNC:4417]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K02564;K02564	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004342//glucosamine-6-phosphate deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0005975//carbohydrate metabolic process;GO:0006043//glucosamine catabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0007338//single fertilization;GO:0019262//N-acetylneuraminate catabolic process	--
ENSG00000113555	0.228	0.143	0.413	0.297	0.14	0.302	27	17	13	26	14	26	PCDH12	protocadherin 12 [Source:HGNC Symbol;Acc:HGNC:8657]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding	GO:0005977//glycogen metabolic process;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008038//neuron recognition;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0060711//labyrinthine layer development	--
ENSG00000113558	481.799	475.306	462.628	445.424	411.021	456.811	7339	7203	5114	4925	5175	4976	SKP1	S-phase kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10899]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Genetic Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems	"Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Folding, sorting and degradation;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Signal transduction;Environmental adaptation"	ko05200//Pathways in cancer;ko05132//Salmonella infection;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway;ko04710//Circadian rhythm	K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0031519//PcG protein complex	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019904//protein domain specific binding;GO:0097602//cullin family protein binding;GO:1990444//F-box domain binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0035518//histone H2A monoubiquitination;GO:0051457//maintenance of protein location in nucleus;GO:0070936//protein K48-linked ubiquitination;GO:1904668//positive regulation of ubiquitin protein ligase activity	--
ENSG00000113569	5.152	5.04	4.251	3.491	4.44	3.834	550	558	371	280	366	333	NUP155	nucleoporin 155 [Source:HGNC Symbol;Acc:HGNC:8063]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14312;K14312	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0044611//nuclear pore inner ring	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0000972//transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006998//nuclear envelope organization;GO:0015031//protein transport;GO:0036228//protein localization to nuclear inner membrane;GO:0051028//mRNA transport;GO:0086014//atrial cardiac muscle cell action potential	--
ENSG00000113575	28.083	26.185	26.85	24.866	24.497	28.546	2449	2331	1884.65	1666	1956	1974	PPP2CA	protein phosphatase 2 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9299]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Transport and catabolism;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation;Signal transduction;Nervous system;Transport and catabolism	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04140//Autophagy - animal;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway;ko04350//TGF-beta signaling pathway;ko04730//Long-term depression;ko04136//Autophagy - other	K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382;K04382	"GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome"	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0048156//tau protein binding;GO:0050811//GABA receptor binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0001932//regulation of protein phosphorylation;GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process;GO:0007498//mesoderm development;GO:0008380//RNA splicing;GO:0010033//response to organic substance;GO:0010288//response to lead ion;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0019932//second-messenger-mediated signaling;GO:0030111//regulation of Wnt signaling pathway;GO:0030155//regulation of cell adhesion;GO:0030308//negative regulation of cell growth;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0040008//regulation of growth;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0045595//regulation of cell differentiation;GO:0051321//meiotic cell cycle;GO:0051898//negative regulation of protein kinase B signaling;GO:0070262//peptidyl-serine dephosphorylation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1904526//regulation of microtubule binding;GO:1904528//positive regulation of microtubule binding;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000113578	0.827	0.442	0.125	0.12	0.066	0	24	17	7	2	3	0	FGF1	fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K18496;K18496;K18496;K18496;K18496;K18496;K18496;K18496;K18496;K18496;K18496	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0031012//extracellular matrix	GO:0005104//fibroblast growth factor receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0030544//Hsp70 protein binding;GO:0044548//S100 protein binding	GO:0001525//angiogenesis;GO:0001759//organ induction;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0032148//activation of protein kinase B activity;GO:0034605//cellular response to heat;GO:0042060//wound healing;GO:0043406//positive regulation of MAP kinase activity;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051781//positive regulation of cell division;GO:0060681//branch elongation involved in ureteric bud branching;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072163//mesonephric epithelium development;GO:1901509//regulation of endothelial tube morphogenesis;GO:1902533//positive regulation of intracellular signal transduction;GO:1903672//positive regulation of sprouting angiogenesis;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000544//regulation of endothelial cell chemotaxis to fibroblast growth factor	--
ENSG00000113580	10.99	8.559	8.754	5.623	7.211	7.417	1394	1073	778	559	726	711	NR3C1	nuclear receptor subfamily 3 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7978]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05771	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001046//core promoter sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0004879//nuclear receptor activity;GO:0004883//glucocorticoid receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:1990239//steroid hormone binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007165//signal transduction;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0042921//glucocorticoid receptor signaling pathway;GO:0043402//glucocorticoid mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051301//cell division;GO:0071383//cellular response to steroid hormone stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	ESR-like
ENSG00000113583	56.606	56.207	54.119	51.254	50.44	50.24	2569	2564	1814	1723	1934	1659	C5orf15	chromosome 5 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:20656]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000113593	6.192	5.367	5.386	4.753	5.845	5.275	260	236	174	154	205	160	PPWD1	peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0071013//catalytic step 2 spliceosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000113594	3.032	1.659	1.935	1.039	1.548	1.895	534	365	252	164	260	230	LIFR	LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597]	Environmental Information Processing;Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Signal transduction;Cellular community - eukaryotes	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells	K05058;K05058;K05058	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0004896//cytokine receptor activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0019955//cytokine binding	GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0034097//response to cytokine;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway	--
ENSG00000113595	6.203	3.985	3.667	4.301	4.998	4.624	455	298	217	241	259	236	TRIM23	tripartite motif containing 23 [Source:HGNC Symbol;Acc:HGNC:660]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008047//enzyme activator activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019003//GDP binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0016567//protein ubiquitination;GO:0045087//innate immune response;GO:0050790//regulation of catalytic activity	--
ENSG00000113597	8.863	6.617	5.447	4.715	6.324	7.044	317	271.14	163	148	203	203	TRAPPC13	trafficking protein particle complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:25828]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000113600	0	0	0	0	0	0	0	0	0	0	0	0	C9	complement C9 [Source:HGNC Symbol;Acc:HGNC:1358]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: parasitic;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05146//Amoebiasis;ko04610//Complement and coagulation cascades	K04000;K04000;K04000;K04000;K04000	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005515//protein binding	"GO:0001906//cell killing;GO:0002376//immune system process;GO:0006955//immune response;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response;GO:0051260//protein homooligomerization"	--
ENSG00000113615	14.308	12.258	12.043	9.352	9.226	11.238	1847.74	1551.47	1126.06	911.2	1032.92	1052.94	SEC24A	"SEC24 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10703]"	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05130//Pathogenic Escherichia coli infection;ko04141//Protein processing in endoplasmic reticulum	K14007;K14007	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0070971//endoplasmic reticulum exit site	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032374//regulation of cholesterol transport;GO:0042632//cholesterol homeostasis;GO:0050714//positive regulation of protein secretion;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000113621	35.574	29.688	27.916	31.217	28.284	28.08	1293	1269	848	915	999	854	TXNDC15	thioredoxin domain containing 15 [Source:HGNC Symbol;Acc:HGNC:20652]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0045880//positive regulation of smoothened signaling pathway;GO:0060271//cilium assembly	--
ENSG00000113638	6.33	4.965	4.769	4.144	4.43	5.703	715	569	400	350	417	469	TTC33	tetratricopeptide repeat domain 33 [Source:HGNC Symbol;Acc:HGNC:29959]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000113643	26.31	26.921	24.879	20.642	20.68	20.149	1158	1191	783	673	769	645	RARS1	arginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:9870]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01887	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004814//arginine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0034618//arginine binding;GO:0045296//cadherin binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006420//arginyl-tRNA aminoacylation	--
ENSG00000113645	55.725	58.049	62.949	61.684	62.228	58.762	4670	4596	3683	3840	4290	3729	WWC1	WW and C2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29435]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16685;K16685	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0060090//molecular adaptor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0016477//cell migration;GO:0030010//establishment of cell polarity;GO:0032386//regulation of intracellular transport;GO:0035330//regulation of hippo signaling;GO:0035331//negative regulation of hippo signaling;GO:0043410//positive regulation of MAPK cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046621//negative regulation of organ growth"	--
ENSG00000113648	84.748	92.927	89.406	87.104	81.11	92.808	3289	3652	2584	2512	2676	2641	MACROH2A1	macroH2A.1 histone [Source:HGNC Symbol;Acc:HGNC:4740]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000793//condensed chromosome;GO:0001739//sex chromatin;GO:0001740//Barr body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005730//nucleolus;GO:0070062//extracellular exosome"	GO:0000182//rDNA binding;GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0010385//double-stranded methylated DNA binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0007549//dosage compensation;GO:0019216//regulation of lipid metabolic process;GO:0033128//negative regulation of histone phosphorylation;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:0040029//regulation of gene expression, epigenetic;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045815//positive regulation of gene expression, epigenetic;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0061086//negative regulation of histone H3-K27 methylation;GO:0071169//establishment of protein localization to chromatin;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:1901837//negative regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1902750//negative regulation of cell cycle G2/M phase transition;GO:1902882//regulation of response to oxidative stress;GO:1902883//negative regulation of response to oxidative stress;GO:1902884//positive regulation of response to oxidative stress;GO:1903226//positive regulation of endodermal cell differentiation;GO:1904815//negative regulation of protein localization to chromosome, telomeric region"	--
ENSG00000113649	8.259	7.459	7.482	5.74	5.931	6.203	671	618	453	346	415	380	TCERG1	transcription elongation regulator 1 [Source:HGNC Symbol;Acc:HGNC:15630]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12824	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003711//transcription elongation regulator activity;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070063//RNA polymerase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000113657	28.566	32.037	13.693	9.662	15.45	10.272	3157	3556	1119	761	1443	825	DPYSL3	dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0044297//cell body;GO:0045202//synapse;GO:0070382//exocytic vesicle	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0017124//SH3 domain binding;GO:0031005//filamin binding;GO:0035374//chondroitin sulfate binding;GO:0042802//identical protein binding"	GO:0010975//regulation of neuron projection development;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0030334//regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0048666//neuron development;GO:0048678//response to axon injury;GO:0051017//actin filament bundle assembly;GO:0051491//positive regulation of filopodium assembly;GO:0051764//actin crosslink formation;GO:0071345//cellular response to cytokine stimulus	--
ENSG00000113658	12.148	10.18	11.142	8.733	8.678	9.692	1626	1228	1020	797	916	909	SMAD5	SMAD family member 5 [Source:HGNC Symbol;Acc:HGNC:6771]	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K16790;K16790	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0071141//SMAD protein complex;GO:0071144//heteromeric SMAD protein complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0070411//I-SMAD binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001657//ureteric bud development;GO:0001880//Mullerian duct regression;GO:0002051//osteoblast fate commitment;GO:0003161//cardiac conduction system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007281//germ cell development;GO:0009653//anatomical structure morphogenesis;GO:0009880//embryonic pattern specification;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030509//BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051216//cartilage development;GO:0060048//cardiac muscle contraction;GO:0060348//bone development;GO:0060395//SMAD protein signal transduction;GO:0071407//cellular response to organic cyclic compound;GO:0071773//cellular response to BMP stimulus;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090287//regulation of cellular response to growth factor stimulus;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	MH1
ENSG00000113712	50.312	46.569	44.153	44.903	43.096	50.979	3197	2916	2001	1875	2073	2227	CSNK1A1	casein kinase 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2451]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04340//Hedgehog signaling pathway	K08957;K08957;K08957;K08957;K08957;K08957;K08957;K08957	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030877//beta-catenin destruction complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0045095//keratin filament"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019082//viral protein processing;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045104//intermediate filament cytoskeleton organization;GO:0051301//cell division;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904424//regulation of GTP binding	--
ENSG00000113716	22.133	21.329	23.283	21.229	20.646	23.055	2414	2349	1879	1698	1925	1842	HMGXB3	HMG-box containing 3 [Source:HGNC Symbol;Acc:HGNC:28982]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003677//DNA binding	GO:0008150//biological_process	HMG
ENSG00000113719	52.125	55.863	54.641	56.027	56.042	51.058	3104	3311	2333	2476	2820	2195	ERGIC1	endoplasmic reticulum-golgi intermediate compartment 1 [Source:HGNC Symbol;Acc:HGNC:29205]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0016192//vesicle-mediated transport"	--
ENSG00000113721	72.384	79.744	83.833	80.738	83.258	85.138	8103	8856	6793	6719	7662	6971	PDGFRB	platelet derived growth factor receptor beta [Source:HGNC Symbol;Acc:HGNC:8804]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko05230//Central carbon metabolism in cancer	K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089;K05089	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031226//intrinsic component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004992//platelet activating factor receptor activity;GO:0005017//platelet-derived growth factor-activated receptor activity;GO:0005019//platelet-derived growth factor beta-receptor activity;GO:0005102//signaling receptor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0038085//vascular endothelial growth factor binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0048407//platelet-derived growth factor binding	GO:0001525//angiogenesis;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009636//response to toxic substance;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014070//response to organic cyclic compound;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0032355//response to estradiol;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032526//response to retinoic acid;GO:0032956//regulation of actin cytoskeleton organization;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033674//positive regulation of kinase activity;GO:0033993//response to lipid;GO:0034405//response to fluid shear stress;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035441//cell migration involved in vasculogenesis;GO:0035556//intracellular signal transduction;GO:0035789//metanephric mesenchymal cell migration;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0035909//aorta morphogenesis;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0043627//response to estrogen;GO:0045840//positive regulation of mitotic nuclear division;GO:0046488//phosphatidylinositol metabolic process;GO:0046777//protein autophosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048839//inner ear development;GO:0050921//positive regulation of chemotaxis;GO:0055003//cardiac myofibril assembly;GO:0055093//response to hyperoxia;GO:0060326//cell chemotaxis;GO:0060437//lung growth;GO:0060981//cell migration involved in coronary angiogenesis;GO:0061298//retina vasculature development in camera-type eye;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071670//smooth muscle cell chemotaxis;GO:0072075//metanephric mesenchyme development;GO:0072262//metanephric glomerular mesangial cell proliferation involved in metanephros development;GO:0072275//metanephric glomerulus morphogenesis;GO:0072277//metanephric glomerular capillary formation;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0072284//metanephric S-shaped body morphogenesis;GO:0090280//positive regulation of calcium ion import;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000491//positive regulation of hepatic stellate cell activation;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000113722	0.299	0.108	0.11	0.22	0.161	0.411	11	4	3	6	5	11	CDX1	caudal type homeobox 1 [Source:HGNC Symbol;Acc:HGNC:1805]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0009887//animal organ morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0014807//regulation of somitogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060349//bone morphogenesis"	Homeobox
ENSG00000113732	112.214	114.654	111.801	117.376	107.43	118.27	3163	3215	2338	2384	2516	2373	ATP6V0E1	ATPase H+ transporting V0 subunit e1 [Source:HGNC Symbol;Acc:HGNC:863]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02153;K02153;K02153;K02153;K02153;K02153;K02153;K02153;K02153	"GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain"	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042625//ATPase-coupled ion transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0016241//regulation of macroautophagy;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000113734	5.72	5.255	5.524	4.635	5.272	4.442	140	130	100	84	109	79	BNIP1	BCL2 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1082]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08497	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031201//SNARE complex;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005484//SNAP receptor activity;GO:0005515//protein binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006915//apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0016192//vesicle-mediated transport;GO:0016320//endoplasmic reticulum membrane fusion;GO:0043066//negative regulation of apoptotic process;GO:0061025//membrane fusion;GO:0097194//execution phase of apoptosis"	--
ENSG00000113739	7.038	7.013	4.987	5.87	5.071	9.47	621	622	325	371	378	608	STC2	stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm	GO:0005179//hormone activity;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0042803//protein homodimerization activity	GO:0006874//cellular calcium ion homeostasis;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007566//embryo implantation;GO:0010629//negative regulation of gene expression;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0033280//response to vitamin D;GO:0034976//response to endoplasmic reticulum stress;GO:0040015//negative regulation of multicellular organism growth;GO:0043434//response to peptide hormone;GO:0046697//decidualization;GO:0046885//regulation of hormone biosynthetic process;GO:0055074//calcium ion homeostasis;GO:0071456//cellular response to hypoxia;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000113742	30.051	24.173	26.007	24.247	29.49	29.695	3383	2631	2131	2043	2267	2251	CPEB4	cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K02602;K02602	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse;GO:1990124//messenger ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0043022//ribosome binding;GO:0045182//translation regulator activity;GO:0046872//metal ion binding"	GO:0002931//response to ischemia;GO:0006412//translation;GO:0006417//regulation of translation;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0036294//cellular response to decreased oxygen levels;GO:0042149//cellular response to glucose starvation;GO:0043524//negative regulation of neuron apoptotic process;GO:0071230//cellular response to amino acid stimulus;GO:2000766//negative regulation of cytoplasmic translation	--
ENSG00000113749	6.575	6.607	8.023	10.088	7.857	9.135	608	601	560	700	635	628	HRH2	histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04971//Gastric acid secretion	K04150;K04150;K04150	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004969//histamine receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0001696//gastric acid secretion;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0045907//positive regulation of vasoconstriction;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000113758	75.209	79.578	81.88	73.178	68.577	70.703	4449	4721	3397	3060	3581	2947	DBN1	drebrin 1 [Source:HGNC Symbol;Acc:HGNC:2695]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005921//gap junction;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030427//site of polarized growth;GO:0030863//cortical cytoskeleton;GO:0030864//cortical actin cytoskeleton;GO:0042641//actomyosin;GO:0042995//cell projection;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099524//postsynaptic cytosol	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0001701//in utero embryonic development;GO:0007015//actin filament organization;GO:0007399//nervous system development;GO:0010643//cell communication by chemical coupling;GO:0010644//cell communication by electrical coupling;GO:0030154//cell differentiation;GO:0030833//regulation of actin filament polymerization;GO:0031915//positive regulation of synaptic plasticity;GO:0032507//maintenance of protein location in cell;GO:0045773//positive regulation of axon extension;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048699//generation of neurons;GO:0048812//neuron projection morphogenesis;GO:0050773//regulation of dendrite development;GO:0051220//cytoplasmic sequestering of protein;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0098974//postsynaptic actin cytoskeleton organization;GO:1902685//positive regulation of receptor localization to synapse	--
ENSG00000113761	8.162	7.827	8.456	9.908	8.055	7.888	415	444	350	377	367	292	ZNF346	zinc finger protein 346 [Source:HGNC Symbol;Acc:HGNC:16403]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding	-	--
ENSG00000113763	0	0.039	0	0.035	0.042	0.087	0	3	0	2	2	2	UNC5A	unc-5 netrin receptor A [Source:HGNC Symbol;Acc:HGNC:12567]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07521	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0032589//neuron projection membrane;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045121//membrane raft	GO:0005042//netrin receptor activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0031175//neuron projection development;GO:0033564//anterior/posterior axon guidance;GO:0038007//netrin-activated signaling pathway	--
ENSG00000113790	5.332	4.871	5.15	3.801	4.099	3.957	416	386	298	222	273	227	EHHADH	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247]	Metabolism;Cellular Processes;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Endocrine system;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko00650//Butanoate metabolism"	K07514;K07514;K07514;K07514;K07514;K07514;K07514;K07514;K07514;K07514;K07514	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0019899//enzyme binding;GO:0070403//NAD+ binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase	--
ENSG00000113805	3.01	2.685	2.18	2.149	2.22	2.628	329	295	176	174	205	209	CNTN3	contactin 3 [Source:HGNC Symbol;Acc:HGNC:2173]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043005//neuron projection	GO:0005515//protein binding	GO:0007155//cell adhesion	--
ENSG00000113810	2.866	2.604	2.305	1.527	1.814	1.974	297.34	271.69	163	81.48	130.17	141.68	SMC4	structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck"	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0045132//meiotic chromosome segregation;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051383//kinetochore organization;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000113811	27.378	25.919	28.759	24.85	22.839	28.42	837	732	566	508	565	586	SELENOK	selenoprotein K [Source:HGNC Symbol;Acc:HGNC:30394]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002230//positive regulation of defense response to virus by host;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006979//response to oxidative stress;GO:0010742//macrophage derived foam cell differentiation;GO:0018345//protein palmitoylation;GO:0030335//positive regulation of cell migration;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042102//positive regulation of T cell proliferation;GO:0045728//respiratory burst after phagocytosis;GO:0050848//regulation of calcium-mediated signaling;GO:0051223//regulation of protein transport;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:2000406//positive regulation of T cell migration	--
ENSG00000113812	23.001	24.02	21.087	20.75	20.645	21.386	1395	1336	1030	959	1076	974	ACTR8	actin related protein 8 [Source:HGNC Symbol;Acc:HGNC:14672]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005813//centrosome;GO:0031011//Ino80 complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000113838	4.355	4.314	4.809	3.869	3.72	5.324	227	228	172	150	176	176	TBCCD1	TBCC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25546]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0031616//spindle pole centrosome	GO:0005515//protein binding	GO:0008360//regulation of cell shape;GO:0030334//regulation of cell migration;GO:0051661//maintenance of centrosome location;GO:0051684//maintenance of Golgi location	--
ENSG00000113845	27.665	30.18	30.074	22.121	25.645	26.154	940	1030	780	614	763	659	TIMMDC1	translocase of inner mitochondrial membrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1321]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	-	--
ENSG00000113851	12.107	10.583	9.535	8.672	7.992	10.875	509.96	470.83	291	291.81	304	326	CRBN	cereblon [Source:HGNC Symbol;Acc:HGNC:30185]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031334//positive regulation of protein-containing complex assembly;GO:0034766//negative regulation of ion transmembrane transport;GO:0035641//locomotory exploration behavior;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1902607//negative regulation of large conductance calcium-activated potassium channel activity	--
ENSG00000113889	0	0	0	0	0	0	0	0	0	0	0	0	KNG1	kininogen 1 [Source:HGNC Symbol;Acc:HGNC:6383]	Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Cell motility;Signal transduction;Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic;Sensory system;Immune system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04810//Regulation of actin cytoskeleton;ko04022//cGMP-PKG signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko05143//African trypanosomiasis;ko04750//Inflammatory mediator regulation of TRP channels;ko04610//Complement and coagulation cascades	K03898;K03898;K03898;K03898;K03898;K03898;K03898;K03898;K03898	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0030414//peptidase inhibitor activity	GO:0006954//inflammatory response;GO:0007162//negative regulation of cell adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030195//negative regulation of blood coagulation;GO:0042311//vasodilation;GO:0043065//positive regulation of apoptotic process;GO:0045861//negative regulation of proteolysis	--
ENSG00000113905	0	0	0	0	0	0	0	0	0	0	0	0	HRG	histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0031093//platelet alpha granule lumen;GO:0036019//endolysosome;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0019865//immunoglobulin binding;GO:0020037//heme binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0002839//positive regulation of immune response to tumor cell;GO:0006935//chemotaxis;GO:0007162//negative regulation of cell adhesion;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010543//regulation of platelet activation;GO:0010593//negative regulation of lamellipodium assembly;GO:0010951//negative regulation of endopeptidase activity;GO:0015886//heme transport;GO:0016525//negative regulation of angiogenesis;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0030308//negative regulation of cell growth;GO:0032956//regulation of actin cytoskeleton organization;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0042730//fibrinolysis;GO:0043065//positive regulation of apoptotic process;GO:0043254//regulation of protein-containing complex assembly;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050832//defense response to fungus;GO:0051838//cytolysis by host of symbiont cells;GO:0051894//positive regulation of focal adhesion assembly;GO:0051918//negative regulation of fibrinolysis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:2000504//positive regulation of blood vessel remodeling;GO:2001027//negative regulation of endothelial cell chemotaxis	--
ENSG00000113916	13.228	13.466	12.452	11.664	12.736	14.772	860	869	610	586	714	671	BCL6	BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001]	Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: overview;Signal transduction	ko05202//Transcriptional misregulation in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04068//FoxO signaling pathway	K15618;K15618;K15618	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0042382//paraspeckles	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001161//intronic transcription regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001817//regulation of cytokine production;GO:0001953//negative regulation of cell-matrix adhesion;GO:0002376//immune system process;GO:0002467//germinal center formation;GO:0002634//regulation of germinal center formation;GO:0002682//regulation of immune system process;GO:0002829//negative regulation of type 2 immune response;GO:0002903//negative regulation of B cell apoptotic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007266//Rho protein signal transduction;GO:0007283//spermatogenesis;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0030036//actin cytoskeleton organization;GO:0030183//B cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030890//positive regulation of B cell proliferation;GO:0031065//positive regulation of histone deacetylation;GO:0032764//negative regulation of mast cell cytokine production;GO:0035024//negative regulation of Rho protein signal transduction;GO:0042092//type 2 immune response;GO:0042127//regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043380//regulation of memory T cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0048821//erythrocyte development;GO:0050727//regulation of inflammatory response;GO:0050776//regulation of immune response;GO:0051272//positive regulation of cellular component movement;GO:1903464//negative regulation of mitotic cell cycle DNA replication;GO:2000773//negative regulation of cellular senescence"	ZBTB
ENSG00000113924	0.202	0	0.52	0.19	0	1.014	7	0	7	3	0	15	HGD	"homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4892]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K00451;K00451	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004411//homogentisate 1,2-dioxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006520//cellular amino acid metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0006570//tyrosine metabolic process;GO:0006572//tyrosine catabolic process	--
ENSG00000113946	0.178	0.177	0.11	0.24	0.326	0.289	11	11	5	11	17	13	CLDN16	claudin 16 [Source:HGNC Symbol;Acc:HGNC:2037]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006875//cellular metal ion homeostasis;GO:0007155//cell adhesion;GO:0010496//intercellular transport;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0030001//metal ion transport;GO:0070830//bicellular tight junction assembly;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000113966	3.491	3.378	3.416	3.437	2.528	3.621	230	169	144	122	150	131	ARL6	ADP ribosylation factor like GTPase 6 [Source:HGNC Symbol;Acc:HGNC:13210]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005879//axonemal microtubule;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030117//membrane coat;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0006612//protein targeting to membrane;GO:0006886//intracellular protein transport;GO:0007368//determination of left/right symmetry;GO:0007601//visual perception;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0032402//melanosome transport;GO:0050896//response to stimulus;GO:0051258//protein polymerization;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium	--
ENSG00000113971	2.535	2.066	1.622	1.267	1.298	1.256	216.37	165.47	87.7	94.49	114.96	99.62	NPHP3	nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	"GO:0001822//kidney development;GO:0001947//heart looping;GO:0003283//atrial septum development;GO:0007368//determination of left/right symmetry;GO:0016055//Wnt signaling pathway;GO:0030324//lung development;GO:0035469//determination of pancreatic left/right asymmetry;GO:0045494//photoreceptor cell maintenance;GO:0048496//maintenance of animal organ identity;GO:0060027//convergent extension involved in gastrulation;GO:0060271//cilium assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0060993//kidney morphogenesis;GO:0071908//determination of intestine left/right asymmetry;GO:0071909//determination of stomach left/right asymmetry;GO:0071910//determination of liver left/right asymmetry;GO:0072189//ureter development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:2000167//regulation of planar cell polarity pathway involved in neural tube closure"	--
ENSG00000114013	0	0	0	0	0.073	0	0	0	0	0	2	0	CD86	CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Immune disease;Infectious disease: viral;Immune disease;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune system;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05202//Transcriptional misregulation in cancer;ko05322//Systemic lupus erythematosus;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko04620//Toll-like receptor signaling pathway;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K05413;K05413;K05413;K05413;K05413;K05413;K05413;K05413;K05413;K05413;K05413;K05413	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0038023//signaling receptor activity	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002639//positive regulation of immunoglobulin production;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0008284//positive regulation of cell population proliferation;GO:0023035//CD40 signaling pathway;GO:0031295//T cell costimulation;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032761//positive regulation of lymphotoxin A production;GO:0042102//positive regulation of T cell proliferation;GO:0042113//B cell activation;GO:0042130//negative regulation of T cell proliferation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell;GO:0071222//cellular response to lipopolysaccharide;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1990051//activation of protein kinase C activity"	--
ENSG00000114019	25.173	27.62	29.803	34.921	33.804	34.364	2337	2508	1968	2446	2707	2359	AMOTL2	angiomotin like 2 [Source:HGNC Symbol;Acc:HGNC:17812]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06104	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0003365//establishment of cell polarity involved in ameboidal cell migration;GO:0016055//Wnt signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030334//regulation of cell migration;GO:0035329//hippo signaling	--
ENSG00000114021	4.791	6.935	4.01	4.677	6.661	7.608	305	332	168	198	261	254	NIT2	nitrilase family member 2 [Source:HGNC Symbol;Acc:HGNC:29878]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism"	K13566;K13566	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	"GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0050152//omega-amidase activity;GO:0106008//2-oxoglutaramate amidase activity"	GO:0006107//oxaloacetate metabolic process;GO:0006528//asparagine metabolic process;GO:0006541//glutamine metabolic process;GO:0006807//nitrogen compound metabolic process	--
ENSG00000114023	23.206	22.949	21.762	21.771	19.93	20.882	663.27	670.35	500.56	493.72	522.87	456.58	FAM162A	family with sequence similarity 162 member A [Source:HGNC Symbol;Acc:HGNC:17865]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0051402//neuron apoptotic process;GO:0071456//cellular response to hypoxia;GO:0090200//positive regulation of release of cytochrome c from mitochondria	--
ENSG00000114026	8.401	9.341	9.317	8.956	9.453	8.931	325	356	265	236	279	248	OGG1	8-oxoguanine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:8125]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K03660	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	"GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003824//catalytic activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008534//oxidized purine nucleobase lesion DNA N-glycosylase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016829//lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0032357//oxidized purine DNA binding;GO:0034039//8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity"	"GO:0002526//acute inflammatory response;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006285//base-excision repair, AP site formation;GO:0006289//nucleotide-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0008152//metabolic process;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009416//response to light stimulus;GO:0032355//response to estradiol;GO:0033683//nucleotide-excision repair, DNA incision;GO:0043066//negative regulation of apoptotic process;GO:0045007//depurination;GO:0045008//depyrimidination;GO:0045471//response to ethanol;GO:0051593//response to folic acid;GO:0071276//cellular response to cadmium ion;GO:1901291//negative regulation of double-strand break repair via single-strand annealing"	--
ENSG00000114030	16.627	17.532	16.852	15.569	17.367	16.68	1616	1567	1083	1017	1117	1065	KPNA1	karyopherin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6394]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Translation	ko05132//Salmonella infection;ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K23940;K23940;K23940;K23940	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030425//dendrite;GO:0042564//NLS-dependent protein nuclear import complex;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0000018//regulation of DNA recombination;GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0014841//skeletal muscle satellite cell proliferation;GO:0014901//satellite cell activation involved in skeletal muscle regeneration;GO:0015031//protein transport;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0043403//skeletal muscle tissue regeneration;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0099527//postsynapse to nucleus signaling pathway	--
ENSG00000114054	25.184	27.319	28.774	25.401	28.273	23.449	969.7	1049.3	796.3	712.21	903.34	646.31	PCCB	propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K01966;K01966;K01966;K01966;K01966	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0009317//acetyl-CoA carboxylase complex;GO:1902494//catalytic complex	GO:0000166//nucleotide binding;GO:0003989//acetyl-CoA carboxylase activity;GO:0004658//propionyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0009081//branched-chain amino acid metabolic process;GO:0019626//short-chain fatty acid catabolic process;GO:0044281//small molecule metabolic process	--
ENSG00000114062	25.711	23.696	20.382	15.523	20.213	20.416	1931	1618	1110	1008	1222	1045	UBE3A	ubiquitin protein ligase E3A [Source:HGNC Symbol;Acc:HGNC:12496]	Human Diseases;Human Diseases;Genetic Information Processing	"Infectious disease: viral;Cancer: overview;Folding, sorting and degradation"	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis;ko04120//Ubiquitin mediated proteolysis	K10587;K10587;K10587	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001541//ovarian follicle development;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007420//brain development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016567//protein ubiquitination;GO:0030521//androgen receptor signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0032570//response to progesterone;GO:0035037//sperm entry;GO:0042752//regulation of circadian rhythm;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0050847//progesterone receptor signaling pathway;GO:0051865//protein autoubiquitination;GO:0060736//prostate gland growth;GO:0070936//protein K48-linked ubiquitination;GO:1905528//positive regulation of Golgi lumen acidification;GO:2000058//regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000114098	13.163	12.114	11.801	8.924	10.277	12.11	759	673	508	441	501	465	ARMC8	armadillo repeat containing 8 [Source:HGNC Symbol;Acc:HGNC:24999]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034657//GID complex;GO:0035580//specific granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:1904724//tertiary granule lumen	GO:0005515//protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000114107	14.316	11.565	13.463	8.039	9.379	11.018	543	456	372	258	320	316	CEP70	centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043015//gamma-tubulin binding	GO:0060271//cilium assembly;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000114113	0	0	0	0	0	0	0	0	0	0	0	0	RBP2	retinol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9920]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14622	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding	GO:0006776//vitamin A metabolic process;GO:0008544//epidermis development;GO:0015908//fatty acid transport	--
ENSG00000114115	474.832	473.912	532.464	554.025	493.119	539.345	7871	7990	6587	6921	7062	6448	RBP1	retinol binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9919]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0044297//cell body	GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:1904768//all-trans-retinol binding	GO:0002138//retinoic acid biosynthetic process;GO:0006776//vitamin A metabolic process;GO:0015908//fatty acid transport;GO:0030852//regulation of granulocyte differentiation;GO:0033189//response to vitamin A;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0055088//lipid homeostasis	--
ENSG00000114120	24.274	21.625	22.111	19.842	22.982	24.222	2208	1937	1480	1319	1528	1529	SLC25A36	solute carrier family 25 member 36 [Source:HGNC Symbol;Acc:HGNC:25554]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015218//pyrimidine nucleotide transmembrane transporter activity	GO:0000002//mitochondrial genome maintenance;GO:0006864//pyrimidine nucleotide transport;GO:0007005//mitochondrion organization;GO:0051881//regulation of mitochondrial membrane potential;GO:0055085//transmembrane transport;GO:1990519//pyrimidine nucleotide import into mitochondrion	--
ENSG00000114124	0	0	0	0.04	0	0.02	0	0	0	2	0	1	GRK7	G protein-coupled receptor kinase 7 [Source:HGNC Symbol;Acc:HGNC:17031]	Cellular Processes;Organismal Systems;Organismal Systems	Transport and catabolism;Immune system;Sensory system	ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko04744//Phototransduction	K00909;K00909;K00909	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0097381//photoreceptor disc membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0050254//rhodopsin kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus	--
ENSG00000114125	25.149	27.765	23.803	29.666	28.146	32.522	614	655	438	524	547	527	RNF7	ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC:10070]	Human Diseases;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation"	ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis	K10611;K10611	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019788//NEDD8 transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0061663//NEDD8 ligase activity;GO:0097602//cullin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation;GO:0051775//response to redox state	--
ENSG00000114126	24.315	19.962	20.538	16.356	15.69	19.337	1557.88	1518	1046	793	1007	947	TFDP2	transcription factor Dp-2 [Source:HGNC Symbol;Acc:HGNC:11751]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K09392	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0072686//mitotic spindle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007507//heart development;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle"	E2F
ENSG00000114127	3.44	2.479	2.355	1.724	2.017	1.914	563	423	313	215	287	246	XRN1	5'-3' exoribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:30654]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03008//Ribosome biogenesis in eukaryotes;ko03018//RNA degradation	K12618;K12618	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0002151//G-quadruplex RNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004534//5'-3' exoribonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0051880//G-quadruplex DNA binding;GO:0070034//telomerase RNA binding	"GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0016070//RNA metabolic process;GO:0016075//rRNA catabolic process;GO:0017148//negative regulation of translation;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0033574//response to testosterone;GO:0071028//nuclear mRNA surveillance;GO:0071044//histone mRNA catabolic process;GO:0071409//cellular response to cycloheximide;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1905795//cellular response to puromycin"	--
ENSG00000114166	15.885	12.595	15.276	12.604	14.247	19.337	1453	1158	1032	854	1101	1287	KAT2B	lysine acetyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:8638]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Endocrine system;Signal transduction	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04919//Thyroid hormone signaling pathway;ko04330//Notch signaling pathway	K06062;K06062;K06062;K06062	GO:0000123//histone acetyltransferase complex;GO:0000124//SAGA complex;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031672//A band;GO:0031674//I band;GO:0032991//protein-containing complex;GO:0042641//actomyosin;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004145//diamine N-acetyltransferase activity;GO:0004402//histone acetyltransferase activity;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019901//protein kinase binding;GO:0042826//histone deacetylase binding;GO:0061733//peptide-lysine-N-acetyltransferase activity;GO:0140297//DNA-binding transcription factor binding"	"GO:0006282//regulation of DNA repair;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006473//protein acetylation;GO:0007049//cell cycle;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010835//regulation of protein ADP-ribosylation;GO:0016573//histone acetylation;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0018393//internal peptidyl-lysine acetylation;GO:0018394//peptidyl-lysine acetylation;GO:0031063//regulation of histone deacetylation;GO:0032869//cellular response to insulin stimulus;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0043970//histone H3-K9 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045722//positive regulation of gluconeogenesis;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0046600//negative regulation of centriole replication;GO:0048511//rhythmic process;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0060173//limb development;GO:0090043//regulation of tubulin deacetylation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:2000233//negative regulation of rRNA processing"	--
ENSG00000114200	5.96	4.971	5.244	4.999	4.968	5.31	266	246	193	148	210	193	BCHE	butyrylcholinesterase [Source:HGNC Symbol;Acc:HGNC:983]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005641//nuclear envelope lumen;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0072562//blood microparticle	"GO:0001540//amyloid-beta binding;GO:0003824//catalytic activity;GO:0003990//acetylcholinesterase activity;GO:0004104//cholinesterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0019899//enzyme binding;GO:0033265//choline binding;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity"	GO:0006581//acetylcholine catabolic process;GO:0007584//response to nutrient;GO:0007612//learning;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0014016//neuroblast differentiation;GO:0016486//peptide hormone processing;GO:0019695//choline metabolic process;GO:0043279//response to alkaloid;GO:0050783//cocaine metabolic process;GO:0050805//negative regulation of synaptic transmission;GO:0051384//response to glucocorticoid;GO:0051593//response to folic acid	--
ENSG00000114204	0	0	0	0	0	0	0	0	0	0	0	0	SERPINI2	serpin family I member 2 [Source:HGNC Symbol;Acc:HGNC:8945]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030155//regulation of cell adhesion	--
ENSG00000114209	20.994	22.104	22.518	22.737	21.512	24.966	507	577	437	412	452	451	PDCD10	programmed cell death 10 [Source:HGNC Symbol;Acc:HGNC:8761]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0090443//FAR/SIN/STRIPAK complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding	"GO:0001525//angiogenesis;GO:0003158//endothelium development;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030335//positive regulation of cell migration;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0036481//intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:0042542//response to hydrogen peroxide;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0044319//wound healing, spreading of cells;GO:0045747//positive regulation of Notch signaling pathway;GO:0045765//regulation of angiogenesis;GO:0050821//protein stabilization;GO:0051683//establishment of Golgi localization;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0090168//Golgi reassembly;GO:0090316//positive regulation of intracellular protein transport;GO:1903358//regulation of Golgi organization;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000114248	0	0	0	0	0	0	0	0	0	0	0	0	LRRC31	leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000114251	3.675	3.306	2.658	3.93	3.274	2.577	378	347	246	284	307	230	WNT5A	Wnt family member 5A [Source:HGNC Symbol;Acc:HGNC:12784]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Development and regeneration;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444;K00444	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005115//receptor tyrosine kinase-like orphan receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019904//protein domain specific binding;GO:0048018//receptor ligand activity;GO:1902379//chemoattractant activity involved in axon guidance	"GO:0001667//ameboidal-type cell migration;GO:0001736//establishment of planar polarity;GO:0001756//somitogenesis;GO:0001819//positive regulation of cytokine production;GO:0001822//kidney development;GO:0001837//epithelial to mesenchymal transition;GO:0001843//neural tube closure;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001947//heart looping;GO:0002009//morphogenesis of an epithelium;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002088//lens development in camera-type eye;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0003138//primary heart field specification;GO:0003139//secondary heart field specification;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0003323//type B pancreatic cell development;GO:0003344//pericardium morphogenesis;GO:0003401//axis elongation;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0003408//optic cup formation involved in camera-type eye development;GO:0006468//protein phosphorylation;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0007254//JNK cascade;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007442//hindgut morphogenesis;GO:0007494//midgut development;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008595//anterior/posterior axis specification, embryo;GO:0009952//anterior/posterior pattern specification;GO:0010033//response to organic substance;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010820//positive regulation of T cell chemotaxis;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0021891//olfactory bulb interneuron development;GO:0021915//neural tube development;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0030901//midbrain development;GO:0032092//positive regulation of protein binding;GO:0032148//activation of protein kinase B activity;GO:0032722//positive regulation of chemokine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034613//cellular protein localization;GO:0035108//limb morphogenesis;GO:0035567//non-canonical Wnt signaling pathway;GO:0036342//post-anal tail morphogenesis;GO:0036517//chemoattraction of serotonergic neuron axon;GO:0036518//chemorepulsion of dopaminergic neuron axon;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0042472//inner ear morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043032//positive regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0045165//cell fate commitment;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045599//negative regulation of fat cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0045778//positive regulation of ossification;GO:0045807//positive regulation of endocytosis;GO:0045836//positive regulation of meiotic nuclear division;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046546//development of primary male sexual characteristics;GO:0048022//negative regulation of melanin biosynthetic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0048341//paraxial mesoderm formation;GO:0048546//digestive tract morphogenesis;GO:0048570//notochord morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048806//genitalia development;GO:0048812//neuron projection morphogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048850//hypophysis morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050807//regulation of synapse organization;GO:0050919//negative chemotaxis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051216//cartilage development;GO:0051885//positive regulation of timing of anagen;GO:0051964//negative regulation of synapse assembly;GO:0060026//convergent extension;GO:0060028//convergent extension involved in axis elongation;GO:0060029//convergent extension involved in organogenesis;GO:0060065//uterus development;GO:0060067//cervix development;GO:0060068//vagina development;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060157//urinary bladder development;GO:0060324//face development;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060599//lateral sprouting involved in mammary gland duct morphogenesis;GO:0060606//tube closure;GO:0060638//mesenchymal-epithelial cell signaling;GO:0060686//negative regulation of prostatic bud formation;GO:0060744//mammary gland branching involved in thelarche;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0060760//positive regulation of response to cytokine stimulus;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0060775//planar cell polarity pathway involved in gastrula mediolateral intercalation;GO:0060809//mesodermal to mesenchymal transition involved in gastrulation;GO:0060907//positive regulation of macrophage cytokine production;GO:0061036//positive regulation of cartilage development;GO:0061053//somite development;GO:0061347//planar cell polarity pathway involved in outflow tract morphogenesis;GO:0061348//planar cell polarity pathway involved in ventricular septum morphogenesis;GO:0061349//planar cell polarity pathway involved in cardiac right atrium morphogenesis;GO:0061350//planar cell polarity pathway involved in cardiac muscle tissue morphogenesis;GO:0061354//planar cell polarity pathway involved in pericardium morphogenesis;GO:0062009//secondary palate development;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0071219//cellular response to molecule of bacterial origin;GO:0071222//cellular response to lipopolysaccharide;GO:0071277//cellular response to calcium ion;GO:0071300//cellular response to retinoic acid;GO:0071346//cellular response to interferon-gamma;GO:0071425//hematopoietic stem cell proliferation;GO:0071542//dopaminergic neuron differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0090009//primitive streak formation;GO:0090037//positive regulation of protein kinase C signaling;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0090630//activation of GTPase activity;GO:0097325//melanocyte proliferation;GO:0099054//presynapse assembly;GO:0099068//postsynapse assembly;GO:0099175//regulation of postsynapse organization;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:0150012//positive regulation of neuron projection arborization;GO:1900020//positive regulation of protein kinase C activity;GO:1901216//positive regulation of neuron death;GO:1902474//positive regulation of protein localization to synapse;GO:1904861//excitatory synapse assembly;GO:1904862//inhibitory synapse assembly;GO:1904934//negative regulation of cell proliferation in midbrain;GO:1904938//planar cell polarity pathway involved in axon guidance;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1904955//planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:2000052//positive regulation of non-canonical Wnt signaling pathway"	--
ENSG00000114268	2.82	3.004	2.681	3.422	3.375	2.842	196	200	137	154	194	142	PFKFB4	"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:HGNC Symbol;Acc:HGNC:8875]"	Environmental Information Processing;Metabolism	Signal transduction;Carbohydrate metabolism	ko04152//AMPK signaling pathway;ko00051//Fructose and mannose metabolism	K19030;K19030	GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003873//6-phosphofructo-2-kinase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity"	"GO:0006000//fructose metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0016311//dephosphorylation;GO:0046835//carbohydrate phosphorylation"	--
ENSG00000114270	0.183	0.291	0.944	0.204	0.352	0.316	35	56	37	29	57	44	COL7A1	collagen type VII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2214]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K16628	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005590//collagen type VII trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0062023//collagen-containing extracellular matrix	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030414//peptidase inhibitor activity	GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0035987//endodermal cell differentiation	--
ENSG00000114279	0.378	1.784	0.786	1.295	0.384	0.204	39	64	25	18	22	12	FGF12	fibroblast growth factor 12 [Source:HGNC Symbol;Acc:HGNC:3668]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045202//synapse	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0017080//sodium channel regulator activity;GO:0044325//transmembrane transporter binding	GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008344//adult locomotory behavior;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010765//positive regulation of sodium ion transport;GO:0050905//neuromuscular process;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0098908//regulation of neuronal action potential;GO:1902305//regulation of sodium ion transmembrane transport;GO:1905150//regulation of voltage-gated sodium channel activity;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000114302	16.02	16.377	16.94	18.09	20.875	15.685	1861	1903	1392	1345	1624	1336	PRKAR2A	protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K04739	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005930//axoneme;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0031588//nucleotide-activated protein kinase complex;GO:0032991//protein-containing complex;GO:0044853//plasma membrane raft;GO:0070062//extracellular exosome;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0030552//cAMP binding;GO:0031625//ubiquitin protein ligase binding;GO:0034236//protein kinase A catalytic subunit binding	GO:0001932//regulation of protein phosphorylation;GO:0007339//binding of sperm to zona pellucida;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000114315	10.53	13.278	11.066	11.199	12.572	14.346	344	436	267	271	347	341	HES1	hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: specific types;Signal transduction;Replication and repair;Endocrine and metabolic disease	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05224//Breast cancer;ko04330//Notch signaling pathway;ko03460//Fanconi anemia pathway;ko04950//Maturity onset diabetes of the young	K06054;K06054;K06054;K06054;K06054;K06054;K06054	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043398//HLH domain binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046983//protein dimerization activity;GO:0051087//chaperone binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:0071820//N-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0003143//embryonic heart tube morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0003281//ventricular septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010977//negative regulation of neuron projection development;GO:0014070//response to organic cyclic compound;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0021557//oculomotor nerve development;GO:0021558//trochlear nerve development;GO:0021575//hindbrain morphogenesis;GO:0021861//forebrain radial glial cell differentiation;GO:0021915//neural tube development;GO:0021983//pituitary gland development;GO:0021984//adenohypophysis development;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0030513//positive regulation of BMP signaling pathway;GO:0030901//midbrain development;GO:0031016//pancreas development;GO:0035019//somatic stem cell population maintenance;GO:0035315//hair cell differentiation;GO:0035909//aorta morphogenesis;GO:0035910//ascending aorta morphogenesis;GO:0042102//positive regulation of T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043254//regulation of protein-containing complex assembly;GO:0043279//response to alkaloid;GO:0043388//positive regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045598//regulation of fat cell differentiation;GO:0045608//negative regulation of inner ear auditory receptor cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045977//positive regulation of mitotic cell cycle, embryonic;GO:0046331//lateral inhibition;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048469//cell maturation;GO:0048505//regulation of timing of cell differentiation;GO:0048538//thymus development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048711//positive regulation of astrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0048844//artery morphogenesis;GO:0050678//regulation of epithelial cell proliferation;GO:0050767//regulation of neurogenesis;GO:0050768//negative regulation of neurogenesis;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060164//regulation of timing of neuron differentiation;GO:0060253//negative regulation of glial cell proliferation;GO:0060412//ventricular septum morphogenesis;GO:0060675//ureteric bud morphogenesis;GO:0060716//labyrinthine layer blood vessel development;GO:0061009//common bile duct development;GO:0061106//negative regulation of stomach neuroendocrine cell differentiation;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0061626//pharyngeal arch artery morphogenesis;GO:0065003//protein-containing complex assembly;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071398//cellular response to fatty acid;GO:0072012//glomerulus vasculature development;GO:0072049//comma-shaped body morphogenesis;GO:0072050//S-shaped body morphogenesis;GO:0072141//renal interstitial fibroblast development;GO:0072282//metanephric nephron tubule morphogenesis;GO:0090102//cochlea development;GO:0090162//establishment of epithelial cell polarity;GO:0090281//negative regulation of calcium ion import;GO:0097066//response to thyroid hormone;GO:0097084//vascular associated smooth muscle cell development;GO:0097150//neuronal stem cell population maintenance;GO:1905934//negative regulation of cell fate determination;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000227//negative regulation of pancreatic A cell differentiation;GO:2000737//negative regulation of stem cell differentiation;GO:2000974//negative regulation of pro-B cell differentiation;GO:2000978//negative regulation of forebrain neuron differentiation;GO:2000981//negative regulation of inner ear receptor cell differentiation"	bHLH
ENSG00000114316	13.933	15.4	15.612	13.756	14.001	13.405	1031	1152	838	736	883	721	USP4	ubiquitin specific peptidase 4 [Source:HGNC Symbol;Acc:HGNC:12627]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031685//adenosine receptor binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0034394//protein localization to cell surface	--
ENSG00000114331	8.188	5.811	5.094	4.367	3.923	6.642	997	712	469	390	472	542	ACAP2	"ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16469]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12489	GO:0001726//ruffle;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0030029//actin filament-based process;GO:0032456//endocytic recycling;GO:0050790//regulation of catalytic activity;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000114346	5.186	3.566	3.212	3.095	2.377	2.391	332	258	181	138	154	136	ECT2	epithelial cell transforming 2 [Source:HGNC Symbol;Acc:HGNC:3155]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0043229//intracellular organelle;GO:0072686//mitotic spindle;GO:0097149//centralspindlin complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity	"GO:0000281//mitotic cytokinesis;GO:0000902//cell morphogenesis;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0032147//activation of protein kinase activity;GO:0032467//positive regulation of cytokinesis;GO:0035556//intracellular signal transduction;GO:0042307//positive regulation of protein import into nucleus;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043547//positive regulation of GTPase activity;GO:0045666//positive regulation of neuron differentiation;GO:0045859//regulation of protein kinase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051260//protein homooligomerization;GO:0051301//cell division;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0070301//cellular response to hydrogen peroxide;GO:0070830//bicellular tight junction assembly;GO:0071277//cellular response to calcium ion;GO:0071479//cellular response to ionizing radiation;GO:0090630//activation of GTPase activity;GO:2000431//regulation of cytokinesis, actomyosin contractile ring assembly"	--
ENSG00000114349	0	0	0.054	0	0.032	0.037	0	0	3	0	2	2	GNAT1	G protein subunit alpha transducin 1 [Source:HGNC Symbol;Acc:HGNC:4393]	Organismal Systems	Sensory system	ko04744//Phototransduction	K04631	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0032391//photoreceptor connecting cilium;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0097381//photoreceptor disc membrane;GO:0110165//cellular anatomical entity	GO:0000035//acyl binding;GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	"GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007603//phototransduction, visible light;GO:0008283//cell population proliferation;GO:0009416//response to light stimulus;GO:0009642//response to light intensity;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042462//eye photoreceptor cell development;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0050917//sensory perception of umami taste;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0060041//retina development in camera-type eye;GO:0071257//cellular response to electrical stimulus"	--
ENSG00000114353	67.088	68.29	68.887	67.807	65.815	61.861	2922	2960	2223	2143	2444	1997	GNAI2	G protein subunit alpha i2 [Source:HGNC Symbol;Acc:HGNC:4385]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Immune system;Substance dependence;Development and regeneration;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Signal transduction;Endocrine system;Immune system;Nervous system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine system;Environmental adaptation;Endocrine system;Substance dependence;Cellular community - eukaryotes;Nervous system;Infectious disease: bacterial;Digestive system;Endocrine system;Endocrine system;Nervous system;Substance dependence	"ko05200//Pathways in cancer;ko05012//Parkinson disease;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko05133//Pertussis;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression;ko05030//Cocaine addiction"	K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0030496//midbody;GO:0044297//cell body;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007584//response to nutrient;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0030335//positive regulation of cell migration;GO:0032930//positive regulation of superoxide anion generation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0050805//negative regulation of synaptic transmission;GO:0051301//cell division;GO:0051924//regulation of calcium ion transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0140199//negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process;GO:1903614//negative regulation of protein tyrosine phosphatase activity;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000114354	58.435	55.433	58.908	51.517	52.273	61.073	2302	2181	1712	1499	1729	1750	TFG	trafficking from ER to golgi regulator [Source:HGNC Symbol;Acc:HGNC:11758]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05216//Thyroid cancer	K09292;K09292	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048208//COPII vesicle coating	--
ENSG00000114374	5.879	4.199	3.857	2.35	5.177	4.233	988	648	570	348	536	470	USP9Y	ubiquitin specific peptidase 9 Y-linked [Source:HGNC Symbol;Acc:HGNC:12633]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070410//co-SMAD binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007283//spermatogenesis;GO:0016477//cell migration;GO:0016579//protein deubiquitination;GO:0030509//BMP signaling pathway	--
ENSG00000114378	1.095	1.398	1.476	1.345	0.998	1.099	43	56	49	39	35	30	HYAL1	hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:5320]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01197;K01197;K01197	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle;GO:0036117//hyaluranon cable;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004415//hyalurononglucosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0050501//hyaluronan synthase activity"	GO:0000302//response to reactive oxygen species;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0009615//response to virus;GO:0010634//positive regulation of epithelial cell migration;GO:0030207//chondroitin sulfate catabolic process;GO:0030212//hyaluronan metabolic process;GO:0030213//hyaluronan biosynthetic process;GO:0030214//hyaluronan catabolic process;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045766//positive regulation of angiogenesis;GO:0045785//positive regulation of cell adhesion;GO:0045927//positive regulation of growth;GO:0046677//response to antibiotic;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071467//cellular response to pH;GO:0071493//cellular response to UV-B;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1900106//positive regulation of hyaluranon cable assembly	--
ENSG00000114383	9.021	9.318	7.733	8.852	7.612	7.623	307	322	196	227	221	192	TUSC2	"tumor suppressor 2, mitochondrial calcium regulator [Source:HGNC Symbol;Acc:HGNC:17034]"	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0001779//natural killer cell differentiation;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007049//cell cycle;GO:0032700//negative regulation of interleukin-17 production;GO:0032733//positive regulation of interleukin-10 production;GO:0048469//cell maturation;GO:0050829//defense response to Gram-negative bacterium;GO:0051881//regulation of mitochondrial membrane potential;GO:0070945//neutrophil-mediated killing of gram-negative bacterium;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000114388	9.493	10.336	9.644	9.227	8.732	9.048	284	301	209	193	208	197	NPRL2	"NPR2 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:24969]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20405	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:1990130//GATOR1 complex	GO:0004672//protein kinase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006468//protein phosphorylation;GO:0010508//positive regulation of autophagy;GO:0032007//negative regulation of TOR signaling;GO:0033673//negative regulation of kinase activity;GO:0034198//cellular response to amino acid starvation;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000114391	338.421	362.827	324.434	324.143	275.448	252.218	3923	4228	2776	2782	2693	2128	RPL24	ribosomal protein L24 [Source:HGNC Symbol;Acc:HGNC:10325]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02896;K02896	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0010458//exit from mitosis;GO:0021554//optic nerve development;GO:0031290//retinal ganglion cell axon guidance;GO:0060041//retina development in camera-type eye	--
ENSG00000114395	5.1	5.663	5.196	7.31	5.711	5.227	127	144	97	138	122	97	CYB561D2	cytochrome b561 family member D2 [Source:HGNC Symbol;Acc:HGNC:30253]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0140571//transmembrane ascorbate ferrireductase activity;GO:0140575//transmembrane monodehydroascorbate reductase activity	GO:0055085//transmembrane transport;GO:0140576//ascorbate homeostasis	--
ENSG00000114405	3.869	2.889	1.78	2.317	3.023	2.13	70	72	27	37	49	33	C3orf14	chromosome 3 open reading frame 14 [Source:HGNC Symbol;Acc:HGNC:25024]	-	-	-	-	-	-	-	--
ENSG00000114416	59.916	54.381	52.789	53.827	45.958	53.548	2707	2520	1707	1761	1704	1684	FXR1	FMR1 autosomal homolog 1 [Source:HGNC Symbol;Acc:HGNC:4023]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0035770//ribonucleoprotein granule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043025//neuronal cell body;GO:0043034//costamere;GO:0043197//dendritic spine;GO:0044326//dendritic spine neck;GO:0048471//perinuclear region of cytoplasm;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:1902737//dendritic filopodium	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0033592//RNA strand annealing activity;GO:0042803//protein homodimerization activity;GO:0045182//translation regulator activity;GO:0046982//protein heterodimerization activity	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001934//positive regulation of protein phosphorylation;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0007517//muscle organ development;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation;GO:0051489//regulation of filopodium assembly;GO:0060538//skeletal muscle organ development;GO:2000637//positive regulation of gene silencing by miRNA;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000114423	9.084	8.673	8.427	14.159	10.719	13.996	828	793	550	639	681	663	CBLB	Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542]	Cellular Processes;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing	"Transport and catabolism;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Immune system;Immune system;Signal transduction"	ko04144//Endocytosis;ko04120//Ubiquitin mediated proteolysis;ko05162//Measles;ko04910//Insulin signaling pathway;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04012//ErbB signaling pathway	K22517;K22517;K22517;K22517;K22517;K22517;K22517	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0045121//membrane raft	GO:0001784//phosphotyrosine residue binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding;GO:0047690//aspartyltransferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0002669//positive regulation of T cell anergy;GO:0006607//NLS-bearing protein import into nucleus;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0016567//protein ubiquitination;GO:0018193//peptidyl-amino acid modification;GO:0023051//regulation of signaling;GO:0030155//regulation of cell adhesion;GO:0031398//positive regulation of protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0043087//regulation of GTPase activity;GO:0043393//regulation of protein binding;GO:0045732//positive regulation of protein catabolic process;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:2000583//regulation of platelet-derived growth factor receptor-alpha signaling pathway	--
ENSG00000114439	11.753	12.202	9.873	5.748	8.387	9.644	2122	1616	1055	745	1050	898	BBX	BBX high mobility group box domain containing [Source:HGNC Symbol;Acc:HGNC:14422]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0060348//bone development	HMG
ENSG00000114446	19.142	15.418	20.744	13.606	15.06	15.441	871	791	592	487	608	580	IFT57	intraflagellar transport 57 [Source:HGNC Symbol;Acc:HGNC:17367]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease	K04638;K04638	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0030992//intraciliary transport particle B;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0044292//dendrite terminus;GO:0097542//ciliary tip	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0001843//neural tube closure;GO:0001947//heart looping;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007224//smoothened signaling pathway;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0042981//regulation of apoptotic process;GO:0044458//motile cilium assembly;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060271//cilium assembly;GO:0060972//left/right pattern formation;GO:1905515//non-motile cilium assembly	--
ENSG00000114450	4.699	4.655	5.964	4.751	6.028	6.449	605	562	461	461	517	558	GNB4	G protein subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:20731]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538;K04538	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0044877//protein-containing complex binding	GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0021762//substantia nigra development	--
ENSG00000114455	0.033	0	0	0	0	0.045	1	0	0	0	0	1	HHLA2	HERV-H LTR-associating 2 [Source:HGNC Symbol;Acc:HGNC:4905]	-	-	-	-	GO:0005575//cellular_component;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0031295//T cell costimulation;GO:0042104//positive regulation of activated T cell proliferation;GO:0050852//T cell receptor signaling pathway	--
ENSG00000114473	4.884	4.701	2.796	1.739	3.119	2.319	196	201	79	54	90	62	IQCG	IQ motif containing G [Source:HGNC Symbol;Acc:HGNC:25251]	-	-	-	-	GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0030544//Hsp70 protein binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation;GO:0044782//cilium organization	--
ENSG00000114480	11.653	11.078	12.531	12.158	10.919	13.259	680	643	531	518	537	555	GBE1	"1,4-alpha-glucan branching enzyme 1 [Source:HGNC Symbol;Acc:HGNC:4180]"	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K00700;K00700	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0003844//1,4-alpha-glucan branching enzyme activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0043169//cation binding;GO:0102752//1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0043524//negative regulation of neuron apoptotic process	--
ENSG00000114487	0	0	0	0	0	0	0	0	0	0	0	0	MORC1	MORC family CW-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:7198]	-	-	-	-	GO:0001673//male germ cell nucleus;GO:0005634//nucleus	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0001662//behavioral fear response;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0040029//regulation of gene expression, epigenetic;GO:0043046//DNA methylation involved in gamete generation;GO:0044026//DNA hypermethylation;GO:2000143//negative regulation of DNA-templated transcription, initiation"	--
ENSG00000114491	6.81	8.212	9.424	21.547	9.258	6.722	515	546	455	382	514	391	UMPS	uridine monophosphate synthetase [Source:HGNC Symbol;Acc:HGNC:12563]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K13421;K13421;K13421	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004588//orotate phosphoribosyltransferase activity;GO:0004590//orotidine-5'-phosphate decarboxylase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0042802//identical protein binding	GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006222//UMP biosynthetic process;GO:0006225//UDP biosynthetic process;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0008152//metabolic process;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0044205//'de novo' UMP biosynthetic process;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000114503	32.731	29.413	31.943	27.993	29.14	32.236	1346	1234	963	829	997	977	NCBP2	nuclear cap binding protein subunit 2 [Source:HGNC Symbol;Acc:HGNC:7659]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12883;K12883;K12883	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0005846//nuclear cap binding complex;GO:0034518//RNA cap binding complex	GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017069//snRNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0002191//cap-dependent translational initiation;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006408//snRNA export from nucleus;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0008334//histone mRNA metabolic process;GO:0008380//RNA splicing;GO:0016246//RNA interference;GO:0031047//gene silencing by RNA;GO:0031053//primary miRNA processing;GO:0031124//mRNA 3'-end processing;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0035195//gene silencing by miRNA;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045292//mRNA cis splicing, via spliceosome;GO:0046833//positive regulation of RNA export from nucleus;GO:0051028//mRNA transport;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain"	--
ENSG00000114520	18.828	17.398	17.477	13.097	13.703	15.559	917	827	637	490	537	547	SNX4	sorting nexin 4 [Source:HGNC Symbol;Acc:HGNC:11175]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17919	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005868//cytoplasmic dynein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031201//SNARE complex;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex	GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:1990459//transferrin receptor binding;GO:1990460//leptin receptor binding	GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:1903595//positive regulation of histamine secretion by mast cell;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000114529	0.539	0.8	0.827	0.829	0.773	0.607	25	36	25	22	29	19	C3orf52	chromosome 3 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:26255]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000114541	13.775	11.86	12.868	10.131	11.372	13.302	1346	1114	869	697	865	941	FRMD4B	FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]	-	-	-	-	GO:0001726//ruffle;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction	-	GO:0090162//establishment of epithelial cell polarity	--
ENSG00000114544	29.408	36.258	30.877	39.533	35.465	33.953	1196	1446	962	1213	1211	1038	SLC41A3	solute carrier family 41 member 3 [Source:HGNC Symbol;Acc:HGNC:31046]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity	GO:0006812//cation transport;GO:0098655//cation transmembrane transport	--
ENSG00000114547	0.047	0	0	0	0	0	1	0	0	0	0	0	ROPN1B	rhophilin associated tail protein 1B [Source:HGNC Symbol;Acc:HGNC:31927]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0046982//protein heterodimerization activity	GO:0001932//regulation of protein phosphorylation;GO:0007266//Rho protein signal transduction;GO:0007283//spermatogenesis;GO:0007340//acrosome reaction;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0030317//flagellated sperm motility;GO:0044782//cilium organization;GO:0048240//sperm capacitation;GO:0061512//protein localization to cilium;GO:0061640//cytoskeleton-dependent cytokinesis;GO:0098609//cell-cell adhesion	--
ENSG00000114554	14.18	15.344	15.686	13.403	14.773	14.784	2738	2978	2237	1917	2410	2077	PLXNA1	plexin A1 [Source:HGNC Symbol;Acc:HGNC:9099]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06820	GO:0002116//semaphorin receptor complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity	GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0014910//regulation of smooth muscle cell migration;GO:0030334//regulation of cell migration;GO:0043087//regulation of GTPase activity;GO:0050772//positive regulation of axonogenesis;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0071526//semaphorin-plexin signaling pathway;GO:0097485//neuron projection guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1990138//neuron projection extension	--
ENSG00000114573	44.818	43.474	53.107	35.773	40.669	40.803	3841	3585	2771	2302	2734	2737	ATP6V1A	ATPase H+ transporting V1 subunit A [Source:HGNC Symbol;Acc:HGNC:851]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02145;K02145;K02145;K02145;K02145;K02145;K02145;K02145;K02145;K02145	"GO:0000139//Golgi membrane;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0033176//proton-transporting V-type ATPase complex;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome"	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0015986//ATP synthesis coupled proton transport;GO:0016241//regulation of macroautophagy;GO:0036295//cellular response to increased oxygen levels;GO:0046034//ATP metabolic process;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000114626	5.007	6.269	6.558	6.767	5.841	7.121	197	252	197	200	198	206	ABTB1	ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003746//translation elongation factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006414//translational elongation	--
ENSG00000114631	5.985	8.645	5.342	7.361	7.582	4.996	270	392	178	246	289	164	PODXL2	podocalyxin like 2 [Source:HGNC Symbol;Acc:HGNC:17936]	-	-	-	-	GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding	GO:0007155//cell adhesion;GO:0050901//leukocyte tethering or rolling	--
ENSG00000114638	0.546	0.52	0.354	1.611	1.941	2.116	22	22	11	38	41	32	UPK1B	uroplakin 1B [Source:HGNC Symbol;Acc:HGNC:12578]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0120001//apical plasma membrane urothelial plaque	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0009617//response to bacterium;GO:0030855//epithelial cell differentiation	--
ENSG00000114646	146.719	158.707	161.715	165.737	169.626	156.561	6779	7343	5513	5674	6597	5282	CSPG5	chondroitin sulfate proteoglycan 5 [Source:HGNC Symbol;Acc:HGNC:2467]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030660//Golgi-associated vesicle membrane;GO:0043202//lysosomal lumen;GO:0045202//synapse;GO:0097060//synaptic membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0031103//axon regeneration;GO:0040008//regulation of growth;GO:0046907//intracellular transport;GO:0048858//cell projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0099550//trans-synaptic signaling, modulating synaptic transmission;GO:0106091//glial cell projection elongation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000114648	4.722	4.547	4.37	4.495	4.069	4.387	405	430	292.91	243	302	306	KLHL18	kelch like family member 18 [Source:HGNC Symbol;Acc:HGNC:29120]	-	-	-	-	-	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0051301//cell division;GO:1901992//positive regulation of mitotic cell cycle phase transition	--
ENSG00000114650	33.422	35.134	38.09	39.801	41.318	35.13	2790	2933	2349	2506	2959	2126	SCAP	SREBF chaperone [Source:HGNC Symbol;Acc:HGNC:30634]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032934//sterol binding;GO:0044877//protein-containing complex binding;GO:0051082//unfolded protein binding	GO:0001666//response to hypoxia;GO:0006629//lipid metabolic process;GO:0006955//immune response;GO:0007568//aging;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0019217//regulation of fatty acid metabolic process;GO:0032868//response to insulin;GO:0032933//SREBP signaling pathway;GO:0042304//regulation of fatty acid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0045540//regulation of cholesterol biosynthetic process;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000114654	0	0	0	0.048	0.095	0.025	0	0	0	2	5	1	EFCC1	EF-hand and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25692]	-	-	-	-	GO:0005829//cytosol	GO:0005509//calcium ion binding	-	--
ENSG00000114656	0.243	0.075	0.062	0.061	0.17	0.159	13	5	2	3	10	8	CFAP92	cilia and flagella associated protein 92 (putative) [Source:HGNC Symbol;Acc:HGNC:29231]	-	-	-	-	-	-	-	--
ENSG00000114670	5.762	5.518	4.083	2.605	2.842	2.739	281	305	141	110	112	93	NEK11	NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0035556//intracellular signal transduction;GO:1901990//regulation of mitotic cell cycle phase transition	--
ENSG00000114686	29.293	34.466	29.04	28.633	29.012	26.974	980	1180	734	722	864	682	MRPL3	mitochondrial ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10379]	Genetic Information Processing	Translation	ko03010//Ribosome	K02906	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000114698	7.328	6.549	3.5	5.319	4.088	4.807	344	250	143	143	191	177	PLSCR4	phospholipid scramblase 4 [Source:HGNC Symbol;Acc:HGNC:16497]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0017128//phospholipid scramblase activity;GO:0019899//enzyme binding;GO:0042609//CD4 receptor binding	GO:0017121//plasma membrane phospholipid scrambling;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000114735	5.123	4.67	5.548	6.239	5.442	4.384	221	196	167	191	199	141	HEMK1	HemK methyltransferase family member 1 [Source:HGNC Symbol;Acc:HGNC:24923]	-	-	-	-	GO:0005739//mitochondrion	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0102559//protein-(glutamine-N5) methyltransferase activity	GO:0006306//DNA methylation;GO:0006479//protein methylation;GO:0032259//methylation;GO:0044267//cellular protein metabolic process	--
ENSG00000114737	0.143	0.166	0.162	0.419	0.17	0.131	6	7	5	13	6	4	CISH	cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K04701;K04701	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0001558//regulation of cell growth;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000114738	28.742	31.619	28.376	32.952	32.518	27.12	1291	1404	1008	1115	1223	896	MAPKAPK3	MAPK activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6888]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04370//VEGF signaling pathway	K04444;K04444	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002224//toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032496//response to lipopolysaccharide;GO:0034097//response to cytokine;GO:0035556//intracellular signal transduction;GO:0044351//macropinocytosis;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway	--
ENSG00000114739	0.859	0.745	0.958	0.878	0.867	0.827	210	183	173	159	179	147	ACVR2B	activin A receptor type 2B [Source:HGNC Symbol;Acc:HGNC:174]	Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K13596;K13596;K13596;K13596	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0048179//activin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016362//activin receptor activity, type II;GO:0016740//transferase activity;GO:0017002//activin-activated receptor activity;GO:0019838//growth factor binding;GO:0046872//metal ion binding;GO:0048185//activin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001702//gastrulation with mouth forming second;GO:0001822//kidney development;GO:0001946//lymphangiogenesis;GO:0001974//blood vessel remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007389//pattern specification process;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0009749//response to glucose;GO:0009791//post-embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0030073//insulin secretion;GO:0030324//lung development;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0031016//pancreas development;GO:0032147//activation of protein kinase activity;GO:0032924//activin receptor signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0035265//organ growth;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045669//positive regulation of osteoblast differentiation;GO:0048617//embryonic foregut morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0060021//roof of mouth development;GO:0060836//lymphatic endothelial cell differentiation;GO:0060840//artery development;GO:0060841//venous blood vessel development;GO:0061298//retina vasculature development in camera-type eye;GO:0071363//cellular response to growth factor stimulus;GO:0120163//negative regulation of cold-induced thermogenesis"	--
ENSG00000114742	14.469	12.962	11.091	9.888	10.292	9.984	1083.4	1071.16	665.03	559.13	715.11	573.87	WDR48	WD repeat domain 48 [Source:HGNC Symbol;Acc:HGNC:30914]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15361	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0008584//male gonad development;GO:0016579//protein deubiquitination;GO:0035264//multicellular organism growth;GO:0043588//skin development;GO:0048568//embryonic organ development;GO:0048705//skeletal system morphogenesis;GO:0048872//homeostasis of number of cells;GO:0050679//positive regulation of epithelial cell proliferation;GO:0072520//seminiferous tubule development;GO:1902525//regulation of protein monoubiquitination;GO:1903003//positive regulation of protein deubiquitination;GO:1905168//positive regulation of double-strand break repair via homologous recombination	--
ENSG00000114744	19.352	16.429	16.486	14.095	14.685	16.096	1424	1229	913	781	924	867	COMMD2	COMM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24993]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000114745	27.039	25.744	25.826	25.754	24.435	27.059	1696.6	1628.84	1194.97	1182.87	1274.89	1223.13	GORASP1	golgi reassembly stacking protein 1 [Source:HGNC Symbol;Acc:HGNC:16769]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006487//protein N-linked glycosylation;GO:0006996//organelle organization;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0050774//negative regulation of dendrite morphogenesis;GO:0061951//establishment of protein localization to plasma membrane	--
ENSG00000114757	0.321	0.113	0.283	0.419	0.487	0.684	40	21	19	36	32	28	PEX5L	peroxisomal biogenesis factor 5 like [Source:HGNC Symbol;Acc:HGNC:30024]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13342	GO:0005737//cytoplasm;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0043235//receptor complex	GO:0000268//peroxisome targeting sequence binding;GO:0005052//peroxisome matrix targeting signal-1 binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0016560//protein import into peroxisome matrix, docking;GO:0034220//ion transmembrane transport;GO:0043949//regulation of cAMP-mediated signaling;GO:0098655//cation transmembrane transport"	--
ENSG00000114767	6.191	7.185	6.773	8.273	9.622	9.926	198	231	160	196	260	231	RRP9	"ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0034511//U3 snoRNA binding	GO:0006364//rRNA processing	--
ENSG00000114770	109.054	115.653	125.799	91.536	110.256	103.859	11490	11862	9763	6844	9713	7694	ABCC5	ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56]	Environmental Information Processing;Human Diseases	Membrane transport;Drug resistance: antineoplastic	ko02010//ABC transporters;ko01523//Antifolate resistance	K05668;K05668	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008514//organic anion transmembrane transporter activity;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015216//purine nucleotide transmembrane transporter activity;GO:0015232//heme transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0034634//glutathione transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0015698//inorganic anion transport;GO:0015711//organic anion transport;GO:0015865//purine nucleotide transport;GO:0030213//hyaluronan biosynthetic process;GO:0034775//glutathione transmembrane transport;GO:0035351//heme transmembrane transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0070730//cAMP transport;GO:0070731//cGMP transport;GO:0098838//folate transmembrane transport;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier	--
ENSG00000114771	0	0	0	0	0	0	0	0	0	0	0	0	AADAC	arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity;GO:0019213//deacetylase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0010898//positive regulation of triglyceride catabolic process	--
ENSG00000114779	17.096	16.469	18.169	28.082	22.844	19.999	591	572	461	715	660	500	ABHD14B	abhydrolase domain containing 14B [Source:HGNC Symbol;Acc:HGNC:28235]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process	--
ENSG00000114784	48.114	46.507	43.717	49.919	44.808	59.883	985	957	661	757	775	892	EIF1B	eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792]	-	-	-	-	GO:0005575//cellular_component;GO:0016282//eukaryotic 43S preinitiation complex	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0043024//ribosomal small subunit binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation	--
ENSG00000114786	3.514	2.554	5.288	3.661	5.398	6.638	102.73	90.2	128.86	78.24	128.36	148.39	ABHD14A-ACY1	ABHD14A-ACY1 readthrough [Source:HGNC Symbol;Acc:HGNC:38856]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism	K14677;K14677;K14677;K14677	GO:0005737//cytoplasm	GO:0004046//aminoacylase activity;GO:0016787//hydrolase activity	GO:0006520//cellular amino acid metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000114790	1.384	1.369	1.448	1.474	1.732	1.288	142	147	104	114	132	91	ARHGEF26	Rho guanine nucleotide exchange factor 26 [Source:HGNC Symbol;Acc:HGNC:24490]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05132//Salmonella infection;ko05100//Bacterial invasion of epithelial cells	K13744;K13744	GO:0001726//ruffle;GO:0005829//cytosol;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0001886//endothelial cell morphogenesis;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity;GO:0097178//ruffle assembly	--
ENSG00000114796	20.011	18.062	18.832	11.907	15.743	14.851	2361	1816	1316	1176	1361	1426	KLHL24	kelch like family member 24 [Source:HGNC Symbol;Acc:HGNC:25947]	-	-	-	-	GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0030054//cell junction;GO:0030057//desmosome;GO:0030424//axon;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0045109//intermediate filament organization;GO:0051865//protein autoubiquitination;GO:2000312//regulation of kainate selective glutamate receptor activity	--
ENSG00000114805	8.276	7.619	8.587	5.649	5.665	5.383	1064	987	815	550	614	502	PLCH1	phospholipase C eta 1 [Source:HGNC Symbol;Acc:HGNC:29185]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism	K19006;K19006	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050429//calcium-dependent phospholipase C activity	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000114812	0.315	0.09	0.095	0.372	0.404	0.488	8	3	3	9	9	7	VIPR1	vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04589	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding	"GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation"	--
ENSG00000114841	1.149	0.702	0.997	0.645	0.662	0.374	103	105	109	97	101	62	DNAH1	dynein axonemal heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2940]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0036156//inner dynein arm;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007018//microtubule-based movement;GO:0007288//sperm axoneme assembly;GO:0030317//flagellated sperm motility;GO:0036159//inner dynein arm assembly;GO:0060285//cilium-dependent cell motility;GO:0060294//cilium movement involved in cell motility	--
ENSG00000114850	58.245	57.331	50.137	55.936	54.221	46.054	2741	2454.87	1706	1809	1995	1612	SSR3	signal sequence receptor subunit 3 [Source:HGNC Symbol;Acc:HGNC:11325]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13251	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006614//SRP-dependent cotranslational protein targeting to membrane	--
ENSG00000114853	27.421	26.599	28.381	31.036	28.454	29.139	3126	3048	2359	2621	2656	2417	ZBTB47	zinc finger and BTB domain containing 47 [Source:HGNC Symbol;Acc:HGNC:26955]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000114854	47.72	53.411	61.191	45.191	35.219	36.168	680	765	644	477	424	375	TNNC1	"troponin C1, slow skeletal and cardiac type [Source:HGNC Symbol;Acc:HGNC:11943]"	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko04020//Calcium signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K05865;K05865;K05865;K05865;K05865	GO:0005829//cytosol;GO:0005861//troponin complex;GO:0043292//contractile fiber;GO:1990584//cardiac Troponin complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031013//troponin I binding;GO:0031014//troponin T binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0002086//diaphragm contraction;GO:0003009//skeletal muscle contraction;GO:0006937//regulation of muscle contraction;GO:0010038//response to metal ion;GO:0014883//transition between fast and slow fiber;GO:0032972//regulation of muscle filament sliding speed;GO:0043462//regulation of ATPase activity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000114857	4.04	2.92	2.685	2.256	3.575	2.743	609	443	299	232	456	301	NKTR	natural killer cell triggering receptor [Source:HGNC Symbol;Acc:HGNC:7833]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000114859	17.055	18.473	16.108	18.031	19.315	15.693	1120.11	1208.07	778.56	840.21	1050.55	744	CLCN2	chloride voltage-gated channel 2 [Source:HGNC Symbol;Acc:HGNC:2020]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K05011	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0043204//perikaryon	GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0030324//lung development;GO:0032347//regulation of aldosterone biosynthetic process;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0060041//retina development in camera-type eye;GO:0060689//cell differentiation involved in salivary gland development	--
ENSG00000114861	5.582	5.638	4.212	4.571	6.068	5.007	384	371	221	224	302	233	FOXP1	forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K23582	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001046//core promoter sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002903//negative regulation of B cell apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0010468//regulation of gene expression;GO:0010595//positive regulation of endothelial cell migration;GO:0010629//negative regulation of gene expression;GO:0030316//osteoclast differentiation;GO:0032496//response to lipopolysaccharide;GO:0032651//regulation of interleukin-1 beta production;GO:0032655//regulation of interleukin-12 production;GO:0032680//regulation of tumor necrosis factor production;GO:0032745//positive regulation of interleukin-21 production;GO:0036035//osteoclast development;GO:0042116//macrophage activation;GO:0042117//monocyte activation;GO:0042118//endothelial cell activation;GO:0045655//regulation of monocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048513//animal organ development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0061470//T follicular helper cell differentiation;GO:1900424//regulation of defense response to bacterium;GO:1901256//regulation of macrophage colony-stimulating factor production;GO:1901509//regulation of endothelial tube morphogenesis;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production"	Fork_head
ENSG00000114867	135.806	141.164	149.335	141.011	148.473	148.944	12322	12980	10222	9873	11260	9967	EIF4G1	eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]	Human Diseases	Cardiovascular disease	ko05416//Viral myocarditis	K03260	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex	"GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008135//translation factor activity, RNA binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0031369//translation initiation factor binding;GO:0042802//identical protein binding;GO:0060090//molecular adaptor activity"	GO:0001662//behavioral fear response;GO:0002191//cap-dependent translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0010507//negative regulation of autophagy;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010942//positive regulation of cell death;GO:0030307//positive regulation of cell growth;GO:0031669//cellular response to nutrient levels;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032502//developmental process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034645//cellular macromolecule biosynthetic process;GO:0036493//positive regulation of translation in response to endoplasmic reticulum stress;GO:0045666//positive regulation of neuron differentiation;GO:0060964//regulation of gene silencing by miRNA;GO:0080135//regulation of cellular response to stress;GO:0097009//energy homeostasis;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1901215//negative regulation of neuron death;GO:1905537//positive regulation of eukaryotic translation initiation factor 4F complex assembly;GO:1905606//regulation of presynapse assembly;GO:1905612//positive regulation of mRNA cap binding;GO:1905618//positive regulation of miRNA mediated inhibition of translation;GO:1905696//regulation of polysome binding	--
ENSG00000114902	58.226	59.997	58.228	57.102	55.078	55.496	1321.78	1372.73	972.5	957.1	1051.62	921	SPCS1	signal peptidase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23401]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K12946	GO:0005783//endoplasmic reticulum;GO:0005787//signal peptidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0043022//ribosome binding	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0019068//virion assembly;GO:0019082//viral protein processing;GO:0045047//protein targeting to ER	--
ENSG00000114904	7.648	7.775	7.127	5.891	7.923	7.242	555.22	593.27	407.5	329.9	434.38	384	NEK4	NIMA related kinase 4 [Source:HGNC Symbol;Acc:HGNC:11399]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division;GO:2000772//regulation of cellular senescence;GO:2001020//regulation of response to DNA damage stimulus"	--
ENSG00000114923	4.088	4.929	4.425	4.186	4.549	4.453	349	368	264	268	328	278	SLC4A3	solute carrier family 4 member 3 [Source:HGNC Symbol;Acc:HGNC:11029]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008509//anion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0061337//cardiac conduction;GO:0086001//cardiac muscle cell action potential;GO:0098656//anion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000114933	2.629	1.103	2.167	3.341	1.555	1.193	436	325	278	194	295	224	INO80D	INO80 complex subunit D [Source:HGNC Symbol;Acc:HGNC:25997]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex	-	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000114942	171.016	172.913	168.906	185.821	156.89	153.33	2720	2784	2012	2165	2118	1797	EEF1B2	eukaryotic translation elongation factor 1 beta 2 [Source:HGNC Symbol;Acc:HGNC:3208]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex	GO:0003746//translation elongation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0050790//regulation of catalytic activity	--
ENSG00000114948	6.119	4.796	4.615	5.01	6.004	4.089	426	396	230	255	306	264	ADAM23	ADAM metallopeptidase domain 23 [Source:HGNC Symbol;Acc:HGNC:202]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000114956	17.921	18.761	18.57	17.328	15.532	18.365	353	371	275	248	258	262	DGUOK	deoxyguanosine kinase [Source:HGNC Symbol;Acc:HGNC:2858]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00904;K00904	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004136//deoxyadenosine kinase activity;GO:0004138//deoxyguanosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019136//deoxynucleoside kinase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006468//protein phosphorylation;GO:0006754//ATP biosynthetic process;GO:0008617//guanosine metabolic process;GO:0009117//nucleotide metabolic process;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0010977//negative regulation of neuron projection development;GO:0016310//phosphorylation;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0044249//cellular biosynthetic process;GO:0046070//dGTP metabolic process;GO:0046122//purine deoxyribonucleoside metabolic process;GO:0106383//dAMP salvage;GO:1901576//organic substance biosynthetic process	--
ENSG00000114978	21.851	16.958	17.826	14.663	17.238	18.094	2219	1731	1337	1103	1479	1337	MOB1A	MOB kinase activator 1A [Source:HGNC Symbol;Acc:HGNC:16015]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K06685;K06685	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity;GO:0035329//hippo signaling	--
ENSG00000114982	17.686	18.32	19.491	17.165	17.283	19.219	1838	1924	1432	1341	1503	1477	KANSL3	KAT8 regulatory NSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25473]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0044545//NSL complex	-	"GO:0006325//chromatin organization;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000114988	17.108	19.295	21.426	18.236	17.199	17.42	832	953	775	657	718	622	LMAN2L	"lectin, mannose binding 2 like [Source:HGNC Symbol;Acc:HGNC:19263]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006457//protein folding;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0015031//protein transport	--
ENSG00000114993	15.84	20.668	19.939	22.094	21.167	21.129	725	928	695	750	818	708	RTKN	rhotekin [Source:HGNC Symbol;Acc:HGNC:10466]	-	-	-	-	GO:0005575//cellular_component;GO:0005826//actomyosin contractile ring;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031267//small GTPase binding	GO:0000281//mitotic cytokinesis;GO:0000915//actomyosin contractile ring assembly;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0031106//septin ring organization;GO:0032185//septin cytoskeleton organization;GO:0042981//regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity	--
ENSG00000114999	3.021	2.703	2.951	2.751	2.636	2.67	894	804	645	603	659	575	TTL	tubulin tyrosine ligase [Source:HGNC Symbol;Acc:HGNC:21586]	-	-	-	-	GO:0005876//spindle microtubule	GO:0000166//nucleotide binding;GO:0004835//tubulin-tyrosine ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018166//C-terminal protein-tyrosinylation;GO:0030516//regulation of axon extension;GO:0045931//positive regulation of mitotic cell cycle;GO:0090235//regulation of metaphase plate congression	--
ENSG00000115008	0	0.048	0	0.129	0	0.066	0	2	0	4	0	2	IL1A	interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signaling molecules and interaction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Endocrine and metabolic disease;Cell growth and death;Immune disease;Cell growth and death;Infectious disease: viral;Infectious disease: parasitic;Cardiovascular disease;Development and regeneration;Endocrine and metabolic disease;Infectious disease: bacterial;Immune disease;Endocrine and metabolic disease;Immune disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05020//Prion disease;ko05152//Tuberculosis;ko05164//Influenza A;ko04640//Hematopoietic cell lineage;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko05162//Measles;ko05140//Leishmaniasis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383;K04383	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005507//copper ion binding;GO:0005515//protein binding	GO:0001660//fever generation;GO:0001666//response to hypoxia;GO:0001819//positive regulation of cytokine production;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0002526//acute inflammatory response;GO:0006883//cellular sodium ion homeostasis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007283//spermatogenesis;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0009408//response to heat;GO:0010033//response to organic substance;GO:0010193//response to ozone;GO:0010243//response to organonitrogen compound;GO:0010332//response to gamma radiation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010893//positive regulation of steroid biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0019221//cytokine-mediated signaling pathway;GO:0031424//keratinization;GO:0032308//positive regulation of prostaglandin secretion;GO:0032496//response to lipopolysaccharide;GO:0032743//positive regulation of interleukin-2 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0032956//regulation of actin cytoskeleton organization;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0033591//response to L-ascorbic acid;GO:0034605//cellular response to heat;GO:0035234//ectopic germ cell programmed cell death;GO:0042060//wound healing;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045766//positive regulation of angiogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046688//response to copper ion;GO:0050714//positive regulation of protein secretion;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051781//positive regulation of cell division;GO:0051930//regulation of sensory perception of pain;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1902624//positive regulation of neutrophil migration;GO:1904445//negative regulation of establishment of Sertoli cell barrier;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000115009	0	0	0	0	0	0	0	0	0	0	0	0	CCL20	C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619]	Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system;Immune disease;Signal transduction;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko05323//Rheumatoid arthritis;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway	K14625;K14625;K14625;K14625;K14625;K14625	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031731//CCR6 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0030593//neutrophil chemotaxis;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042742//defense response to bacterium;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0072678//T cell migration;GO:0072679//thymocyte migration;GO:2000406//positive regulation of T cell migration	--
ENSG00000115020	12.527	10.684	11.301	7.966	9.379	11.082	2332	1895	1475	1052	1408	1467	PIKFYVE	"phosphoinositide kinase, FYVE-type zinc finger containing [Source:HGNC Symbol;Acc:HGNC:23785]"	Metabolism;Cellular Processes;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Cell motility;Transport and catabolism;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04810//Regulation of actin cytoskeleton;ko04145//Phagosome;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00921;K00921;K00921;K00921;K00921	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0010008//endosome membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	"GO:0000166//nucleotide binding;GO:0000285//1-phosphatidylinositol-3-phosphate 5-kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016740//transferase activity;GO:0016887//ATP hydrolysis activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0046872//metal ion binding;GO:0052810//1-phosphatidylinositol-5-kinase activity;GO:0106310//protein serine kinase activity"	"GO:0006612//protein targeting to membrane;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016310//phosphorylation;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030593//neutrophil chemotaxis;GO:0032288//myelin assembly;GO:0032438//melanosome organization;GO:0034504//protein localization to nucleus;GO:0035556//intracellular signal transduction;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0036289//peptidyl-serine autophosphorylation;GO:0042147//retrograde transport, endosome to Golgi;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0090382//phagosome maturation;GO:0090385//phagosome-lysosome fusion;GO:1903100//1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1904562//phosphatidylinositol 5-phosphate metabolic process;GO:2000785//regulation of autophagosome assembly"	--
ENSG00000115041	2.964	3.96	2.747	2.936	2.544	2.787	173	201	112	121	114	115	KCNIP3	potassium voltage-gated channel interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:15523]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000115042	52.12	52.554	44.607	40.346	44.123	46.575	1630.48	1669.51	1073.49	944.2	1076.21	1129.58	FAHD2A	fumarylacetoacetate hydrolase domain containing 2A [Source:HGNC Symbol;Acc:HGNC:24252]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	-	--
ENSG00000115053	136.153	138.632	119.597	94.669	103.043	82.692	6796	6960	4367	3480	4305	2931	NCL	nucleolin [Source:HGNC Symbol;Acc:HGNC:7667]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K11294	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042162//telomeric DNA binding;GO:0042802//identical protein binding;GO:0044547//DNA topoisomerase binding;GO:0048027//mRNA 5'-UTR binding;GO:0140297//DNA-binding transcription factor binding	"GO:0001525//angiogenesis;GO:0017148//negative regulation of translation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000115073	25.178	25.027	27.9	25.81	23.069	28.651	1151	1150	942	874	891	953	ACTR1B	actin related protein 1B [Source:HGNC Symbol;Acc:HGNC:168]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection	K16575;K16575;K16575;K16575	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000115084	47.443	52.257	50.801	38.879	40.221	41.478	3405	3017	2310	1785	2093	2089	SLC35F5	solute carrier family 35 member F5 [Source:HGNC Symbol;Acc:HGNC:23617]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0090087//regulation of peptide transport	--
ENSG00000115085	0.02	0	0	0	0.058	0	1	0	0	0	2	0	ZAP70	zeta chain of T cell receptor associated protein kinase 70 [Source:HGNC Symbol;Acc:HGNC:12858]	Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: bacterial;Immune system;Signal transduction;Immune disease;Immune system;Immune system;Immune system;Cancer: overview	ko04014//Ras signaling pathway;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K07360;K07360;K07360;K07360;K07360;K07360;K07360;K07360;K07360	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042101//T cell receptor complex;GO:0045121//membrane raft	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030217//T cell differentiation;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0043366//beta selection;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0045061//thymic T cell selection;GO:0045087//innate immune response;GO:0045582//positive regulation of T cell differentiation;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0046777//protein autophosphorylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050852//T cell receptor signaling pathway;GO:0070489//T cell aggregation;GO:0072678//T cell migration	--
ENSG00000115091	71.103	64.086	58.976	58.905	60.03	53.293	3528	3135	2159	2050	2221	2024	ACTR3	actin related protein 3 [Source:HGNC Symbol;Acc:HGNC:170]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0035861//site of double-strand break;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0008356//asymmetric cell division;GO:0010592//positive regulation of lamellipodium assembly;GO:0016344//meiotic chromosome movement towards spindle pole;GO:0030030//cell projection organization;GO:0033206//meiotic cytokinesis;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051321//meiotic cell cycle;GO:0051653//spindle localization;GO:0060271//cilium assembly;GO:0070358//actin polymerization-dependent cell motility;GO:0071346//cellular response to interferon-gamma	--
ENSG00000115107	0.906	0.959	0.353	0.384	0.745	0.532	52	72	23	24	44	22	STEAP3	STEAP3 metalloreductase [Source:HGNC Symbol;Acc:HGNC:24592]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04115//p53 signaling pathway;ko04216//Ferroptosis	K10142;K10142	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0008823//cupric reductase activity;GO:0016491//oxidoreductase activity;GO:0016723//oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0052851//ferric-chelate reductase (NADPH) activity"	GO:0006811//ion transport;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0009306//protein secretion;GO:0015677//copper ion import;GO:0033572//transferrin transport;GO:0055072//iron ion homeostasis	--
ENSG00000115109	8.823	7.433	7.733	6.54	6.685	7.51	1078	895	725	543	700	669	EPB41L5	erythrocyte membrane protein band 4.1 like 5 [Source:HGNC Symbol;Acc:HGNC:19819]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0032587//ruffle membrane	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding	"GO:0000904//cell morphogenesis involved in differentiation;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001839//neural plate morphogenesis;GO:0001954//positive regulation of cell-matrix adhesion;GO:0003382//epithelial cell morphogenesis;GO:0003383//apical constriction;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0007398//ectoderm development;GO:0007492//endoderm development;GO:0007498//mesoderm development;GO:0007509//mesoderm migration involved in gastrulation;GO:0009826//unidimensional cell growth;GO:0010608//posttranscriptional regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0022408//negative regulation of cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032525//somite rostral/caudal axis specification;GO:0048318//axial mesoderm development;GO:0048319//axial mesoderm morphogenesis;GO:0048339//paraxial mesoderm development;GO:0048617//embryonic foregut morphogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0070201//regulation of establishment of protein localization;GO:0070986//left/right axis specification;GO:0071560//cellular response to transforming growth factor beta stimulus"	--
ENSG00000115112	2.092	2.056	1.357	0.708	1.204	0.763	403	398	193	101	196	107	TFCP2L1	transcription factor CP2 like 1 [Source:HGNC Symbol;Acc:HGNC:17925]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0002070//epithelial cell maturation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007028//cytoplasm organization;GO:0007431//salivary gland development;GO:0008340//determination of adult lifespan;GO:0045927//positive regulation of growth;GO:0045944//positive regulation of transcription by RNA polymerase II	CP2
ENSG00000115128	38.954	42.955	41.914	38.692	34.099	38.576	526	583	418	387	389	379	SF3B6	splicing factor 3b subunit 6 [Source:HGNC Symbol;Acc:HGNC:30096]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12833	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001825//blastocyst formation;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000115129	15.097	18.108	18.226	17.041	12.965	15.823	365	451	312	312	257	282	TP53I3	tumor protein p53 inducible protein 3 [Source:HGNC Symbol;Acc:HGNC:19373]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10133	GO:0005829//cytosol	GO:0003960//NADPH:quinone reductase activity;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity;GO:0048038//quinone binding;GO:0070402//NADPH binding	GO:0006739//NADP metabolic process	--
ENSG00000115137	2.064	1.307	1.997	1.539	1.471	1.6	174	132	114	91	113	117	DNAJC27	DnaJ heat shock protein family (Hsp40) member C27 [Source:HGNC Symbol;Acc:HGNC:30290]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0043410//positive regulation of MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071701//regulation of MAPK export from nucleus	--
ENSG00000115138	0	0	0	0	0	0	0	0	0	0	0	0	POMC	proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome;ko04915//Estrogen signaling pathway;ko04916//Melanogenesis;ko04925//Aldosterone synthesis and secretion;ko04920//Adipocytokine signaling pathway;ko04927//Cortisol synthesis and secretion	K05228;K05228;K05228;K05228;K05228;K05228;K05228;K05228	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030141//secretory granule;GO:0034774//secretory granule lumen	GO:0001664//G protein-coupled receptor binding;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031781//type 3 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0070996//type 1 melanocortin receptor binding	GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0008217//regulation of blood pressure;GO:0019722//calcium-mediated signaling;GO:0032098//regulation of appetite;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033059//cellular pigmentation;GO:0042593//glucose homeostasis;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070873//regulation of glycogen metabolic process;GO:0140668//positive regulation of oxytocin production;GO:1990680//response to melanocyte-stimulating hormone;GO:2000852//regulation of corticosterone secretion	--
ENSG00000115145	6.317	4.944	5.046	4.211	3.754	4.747	717	564	423	354	360	392	STAM2	signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04630//JAK-STAT signaling pathway	K04705;K04705	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0031901//early endosome membrane;GO:0033565//ESCRT-0 complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly	--
ENSG00000115155	0.413	0.041	0.047	0.028	0.041	0.057	8	6	5	3	5	6	OTOF	otoferlin [Source:HGNC Symbol;Acc:HGNC:8515]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048787//presynaptic active zone membrane;GO:0098793//presynapse	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0035612//AP-2 adaptor complex binding;GO:0046872//metal ion binding	GO:0007009//plasma membrane organization;GO:0007605//sensory perception of sound;GO:0016079//synaptic vesicle exocytosis;GO:0016082//synaptic vesicle priming;GO:0061025//membrane fusion	--
ENSG00000115159	3.95	3.893	3.838	2.852	2.961	4.029	465	455	329	244	298	303	GPD2	glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K00111	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0009331//glycerol-3-phosphate dehydrogenase complex	GO:0004368//glycerol-3-phosphate dehydrogenase (quinone) activity;GO:0005509//calcium ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0052590//sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity;GO:0052591//sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	GO:0006072//glycerol-3-phosphate metabolic process;GO:0006127//glycerophosphate shuttle;GO:0019563//glycerol catabolic process	--
ENSG00000115163	0.243	0.242	0.094	0.15	0.247	0.255	7	7	2	3	6	5	CENPA	centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0000786//nucleosome;GO:0000939//inner kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005829//cytosol;GO:0043505//CENP-A containing nucleosome"	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0000132//establishment of mitotic spindle orientation;GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0051301//cell division;GO:0051382//kinetochore assembly;GO:0061644//protein localization to CENP-A containing chromatin;GO:0071459//protein localization to chromosome, centromeric region"	Others
ENSG00000115165	1.212	0.848	0.71	1.032	0.75	1.201	49	39	24	35	29	40	CYTIP	cytohesin 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:9506]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005938//cell cortex	GO:0005515//protein binding	GO:0030155//regulation of cell adhesion	--
ENSG00000115170	19.141	19.182	15.993	12.61	13.51	15.528	1183	1204	731	571	707	704	ACVR1	activin A receptor type 1 [Source:HGNC Symbol;Acc:HGNC:171]	Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K04675;K04675;K04675;K04675	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0045177//apical part of cell;GO:0048179//activin receptor complex;GO:0070724//BMP receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016361//activin receptor activity, type I;GO:0016740//transferase activity;GO:0017046//peptide hormone binding;GO:0019838//growth factor binding;GO:0042803//protein homodimerization activity;GO:0043167//ion binding;GO:0045296//cadherin binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding;GO:1990782//protein tyrosine kinase binding"	"GO:0001569//branching involved in blood vessel morphogenesis;GO:0001655//urogenital system development;GO:0001701//in utero embryonic development;GO:0001702//gastrulation with mouth forming second;GO:0001707//mesoderm formation;GO:0001755//neural crest cell migration;GO:0002526//acute inflammatory response;GO:0003143//embryonic heart tube morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003274//endocardial cushion fusion;GO:0003289//atrial septum primum morphogenesis;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007281//germ cell development;GO:0007368//determination of left/right symmetry;GO:0007369//gastrulation;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0009953//dorsal/ventral pattern formation;GO:0009968//negative regulation of signal transduction;GO:0010604//positive regulation of macromolecule metabolic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030278//regulation of ossification;GO:0030335//positive regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048641//regulation of skeletal muscle tissue development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051145//smooth muscle cell differentiation;GO:0051173//positive regulation of nitrogen compound metabolic process;GO:0051239//regulation of multicellular organismal process;GO:0060037//pharyngeal system development;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060412//ventricular septum morphogenesis;GO:0060923//cardiac muscle cell fate commitment;GO:0061312//BMP signaling pathway involved in heart development;GO:0061445//endocardial cushion cell fate commitment;GO:0071363//cellular response to growth factor stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071773//cellular response to BMP stimulus;GO:0080090//regulation of primary metabolic process;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:2000017//positive regulation of determination of dorsal identity;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000115183	29.662	28.168	26.821	19.957	23.074	24.504	4615	4405	3082	2300	3033	2774	TANC1	"tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 [Source:HGNC Symbol;Acc:HGNC:29364]"	-	-	-	-	GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse	GO:0005515//protein binding	GO:0007520//myoblast fusion;GO:0008542//visual learning;GO:0097062//dendritic spine maintenance	--
ENSG00000115194	0	0	0	0.044	0.19	0.318	0	0	0	2	3	4	SLC30A3	solute carrier family 30 member 3 [Source:HGNC Symbol;Acc:HGNC:11014]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:0097457//hippocampal mossy fiber;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0010043//response to zinc ion;GO:0051050//positive regulation of transport;GO:0055085//transmembrane transport;GO:0061088//regulation of sequestering of zinc ion;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport;GO:0099180//zinc ion import into synaptic vesicle	--
ENSG00000115204	57.558	60.534	54.8	60.969	64.965	64.772	1185	1246	837	928	1131	974	MPV17	mitochondrial inner membrane protein MPV17 [Source:HGNC Symbol;Acc:HGNC:7224]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13348	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015267//channel activity	GO:0000002//mitochondrial genome maintenance;GO:0032836//glomerular basement membrane development;GO:0034614//cellular response to reactive oxygen species;GO:0042592//homeostatic process;GO:0048839//inner ear development;GO:0055085//transmembrane transport;GO:1901858//regulation of mitochondrial DNA metabolic process;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000115207	28.063	26.633	27.671	26.474	29.528	26.962	2013	1946	1471	1406	1696	1384	GTF3C2	general transcription factor IIIC subunit 2 [Source:HGNC Symbol;Acc:HGNC:4665]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III	--
ENSG00000115211	17.795	16.563	19.624	17.404	17.114	20.059	599	558	470	428	479	468	EIF2B4	eukaryotic translation initiation factor 2B subunit delta [Source:HGNC Symbol;Acc:HGNC:3260]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K03680	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex	GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	GO:0001541//ovarian follicle development;GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0014003//oligodendrocyte development;GO:0042552//myelination;GO:0043434//response to peptide hormone;GO:0044237//cellular metabolic process;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000115216	50.238	53.096	58.327	54.484	52.468	57.036	2429	2577	2069	1953	2130	1973	NRBP1	nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity	GO:0006468//protein phosphorylation;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0035556//intracellular signal transduction	--
ENSG00000115221	0.022	0.044	0.055	0.015	0.061	0	2	4	3	1	5	0	ITGB6	integrin subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:6161]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06589;K06589;K06589;K06589;K06589;K06589;K06589;K06589	GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034685//integrin alphav-beta6 complex;GO:0043235//receptor complex	GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0000902//cell morphogenesis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0009611//response to wounding;GO:0009615//response to virus;GO:0010467//gene expression;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0042060//wound healing;GO:0043129//surfactant homeostasis;GO:0043588//skin development;GO:0046718//viral entry into host cell;GO:0048286//lung alveolus development;GO:0055091//phospholipid homeostasis;GO:0060022//hard palate development;GO:0060348//bone development;GO:0060395//SMAD protein signal transduction;GO:0060435//bronchiole development;GO:0061520//Langerhans cell differentiation;GO:0070166//enamel mineralization;GO:0071479//cellular response to ionizing radiation;GO:0071604//transforming growth factor beta production;GO:1901388//regulation of transforming growth factor beta activation	--
ENSG00000115226	4.008	4.017	3.604	3.19	2.938	3.247	134	135	89	79	83	79	FNDC4	fibronectin type III domain containing 4 [Source:HGNC Symbol;Acc:HGNC:20239]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0050728//negative regulation of inflammatory response;GO:0071559//response to transforming growth factor beta	--
ENSG00000115232	0.529	0.373	0.222	0.137	0.185	0.124	74.47	49.17	23.05	14.31	17.88	6.5	ITGA4	integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: parasitic;Immune system;Immune system;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko04672//Intestinal immune network for IgA production;ko04670//Leukocyte transendothelial migration;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483;K06483	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0034668//integrin alpha4-beta1 complex;GO:0034669//integrin alpha4-beta7 complex;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0001968//fibronectin binding;GO:0003823//antigen binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0019960//C-X3-C chemokine binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:1990405//protein antigen binding	GO:0002687//positive regulation of leukocyte migration;GO:0003366//cell-matrix adhesion involved in ameboidal cell migration;GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0033631//cell-cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035987//endodermal cell differentiation;GO:0043113//receptor clustering;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0050904//diapedesis;GO:0060385//axonogenesis involved in innervation;GO:0071345//cellular response to cytokine stimulus;GO:0090074//negative regulation of protein homodimerization activity;GO:0098609//cell-cell adhesion;GO:0098657//import into cell;GO:0140039//cell-cell adhesion in response to extracellular stimulus;GO:1903039//positive regulation of leukocyte cell-cell adhesion;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:1904646//cellular response to amyloid-beta;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1990138//neuron projection extension;GO:1990771//clathrin-dependent extracellular exosome endocytosis;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000406//positive regulation of T cell migration	--
ENSG00000115233	30.348	30.379	31.587	29.781	28.66	32.901	982	988	754	717	787	774	PSMD14	"proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03030;K03030;K03030;K03030;K03030;K03030;K03030;K03030;K03030	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0022624//proteasome accessory complex;GO:0031597//cytosolic proteasome complex;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen"	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0061133//endopeptidase activator activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070122//isopeptidase activity;GO:0070628//proteasome binding;GO:0140492//metal-dependent deubiquitinase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010950//positive regulation of endopeptidase activity;GO:0016579//protein deubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045471//response to ethanol;GO:0061136//regulation of proteasomal protein catabolic process;GO:0070536//protein K63-linked deubiquitination	--
ENSG00000115234	47.717	48.53	52.81	59.418	52.697	50.636	2293.78	2365.89	1865.75	2132.91	2165.82	1791.89	SNX17	sorting nexin 17 [Source:HGNC Symbol;Acc:HGNC:14979]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0050750//low-density lipoprotein particle receptor binding	GO:0001822//kidney development;GO:0003279//cardiac septum development;GO:0006707//cholesterol catabolic process;GO:0006886//intracellular protein transport;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030100//regulation of endocytosis;GO:0032456//endocytic recycling;GO:0035904//aorta development;GO:0060976//coronary vasculature development	--
ENSG00000115239	8.312	6.575	7.614	7.106	8.246	7.929	359	274	238	224	290	243	ASB3	ankyrin repeat and SOCS box containing 3 [Source:HGNC Symbol;Acc:HGNC:16013]	-	-	-	-	GO:0005829//cytosol;GO:0030315//T-tubule	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0036371//protein localization to T-tubule;GO:0055117//regulation of cardiac muscle contraction	--
ENSG00000115241	51.222	50.634	57.036	46.002	48.337	50.25	2348	2333	1931	1562	1872	1676	PPM1G	"protein phosphatase, Mg2+/Mn2+ dependent 1G [Source:HGNC Symbol;Acc:HGNC:9278]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000115252	0.421	0.202	0.317	0.28	0.371	0.524	21	11	12	10	16	20	PDE1A	phosphodiesterase 1A [Source:HGNC Symbol;Acc:HGNC:8774]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Sensory system;Signal transduction;Nucleotide metabolism;Substance dependence;Sensory system;Endocrine system	ko01100//Metabolic pathways;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04742//Taste transduction;ko04924//Renin secretion	K13755;K13755;K13755;K13755;K13755;K13755;K13755	GO:0005829//cytosol;GO:0043025//neuronal cell body	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0048101//calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction	--
ENSG00000115255	15.456	16.324	21.791	19.622	18.798	16.078	436	463	454	410	448	330	REEP6	receptor accessory protein 6 [Source:HGNC Symbol;Acc:HGNC:30078]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0007029//endoplasmic reticulum organization;GO:0032386//regulation of intracellular transport;GO:0050908//detection of light stimulus involved in visual perception	--
ENSG00000115257	1.367	2.445	2.754	1.706	1.586	1.203	73	114	82	57	63	48	PCSK4	proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031410//cytoplasmic vesicle	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007339//binding of sperm to zona pellucida;GO:0007340//acrosome reaction;GO:0009566//fertilization;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0022414//reproductive process;GO:0048240//sperm capacitation	--
ENSG00000115263	0	0	0	0	0	0	0	0	0	0	0	0	GCG	glucagon [Source:HGNC Symbol;Acc:HGNC:4191]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Environmental adaptation;Signal transduction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04714//Thermogenesis;ko04024//cAMP signaling pathway;ko04922//Glucagon signaling pathway;ko04911//Insulin secretion	K05259;K05259;K05259;K05259;K05259	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0034774//secretory granule lumen	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031769//glucagon receptor binding;GO:0042802//identical protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007631//feeding behavior;GO:0010737//protein kinase A signaling;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0014823//response to activity;GO:0032092//positive regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042593//glucose homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0045722//positive regulation of gluconeogenesis;GO:0045860//positive regulation of protein kinase activity;GO:0050796//regulation of insulin secretion;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090280//positive regulation of calcium ion import;GO:1900118//negative regulation of execution phase of apoptosis	--
ENSG00000115266	5.919	7.47	5.085	5.428	4.176	2.641	623	718	472	427	520	320	APC2	APC regulator of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:24036]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cell motility;Cancer: overview;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05210//Colorectal cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer	K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005884//actin filament;GO:0015630//microtubule cytoskeleton;GO:0016342//catenin complex;GO:0030496//midbody;GO:0030877//beta-catenin destruction complex;GO:0031258//lamellipodium membrane;GO:0031941//filamentous actin;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0098794//postsynapse	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008017//microtubule binding;GO:0045295//gamma-catenin binding	GO:0000226//microtubule cytoskeleton organization;GO:0001708//cell fate specification;GO:0007026//negative regulation of microtubule depolymerization;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045595//regulation of cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090630//activation of GTPase activity	--
ENSG00000115267	2.228	1.913	2.436	1.872	2.739	2.717	157	135	127	100	156	137	IFIH1	interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05164//Influenza A;ko05161//Hepatitis B;ko05162//Measles;ko04622//RIG-I-like receptor signaling pathway	K12647;K12647;K12647;K12647;K12647;K12647	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0009597//detection of virus;GO:0009615//response to virus;GO:0016925//protein sumoylation;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034344//regulation of type III interferon production;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0039530//MDA-5 signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060760//positive regulation of response to cytokine stimulus;GO:0071360//cellular response to exogenous dsRNA;GO:0098586//cellular response to virus	--
ENSG00000115268	478.137	506.266	493.1	533.969	502.897	464.113	4978	5295	3792	4119	4421	3515	RPS15	ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02958;K02958	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0097371//MDM2/MDM4 family protein binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0000028//ribosomal small subunit assembly;GO:0000056//ribosomal small subunit export from nucleus;GO:0001649//osteoblast differentiation;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042274//ribosomal small subunit biogenesis;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000115271	17.254	14.517	16.147	17.788	15.072	17.843	732	633	512	585	552	575	GCA	grancalcin [Source:HGNC Symbol;Acc:HGNC:15990]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0061025//membrane fusion	--
ENSG00000115274	9.36	10.026	12.296	11.75	12.518	14.629	214.73	246.86	210.48	206.99	250	240.73	INO80B	INO80 complex subunit B [Source:HGNC Symbol;Acc:HGNC:13324]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body;GO:0031011//Ino80 complex	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000115275	19.865	20.689	24.113	22.747	24.493	22.037	1120	1211	1013	969	1130	916	MOGS	mannosyl-oligosaccharide glucosidase [Source:HGNC Symbol;Acc:HGNC:24862]	Metabolism;Genetic Information Processing;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis	K01228;K01228;K01228	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0004573//mannosyl-oligosaccharide glucosidase activity;GO:0015926//glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006457//protein folding;GO:0006487//protein N-linked glycosylation;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0019082//viral protein processing	--
ENSG00000115282	4.475	4.886	5.625	4.101	4.236	4.459	268	247	232	181	206	195	TTC31	tetratricopeptide repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:25759]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000115286	66.414	69.488	74.039	90.653	94.928	79.533	1086	1128	889	1087	1300	955	NDUFS7	NADH:ubiquinone oxidoreductase core subunit S7 [Source:HGNC Symbol;Acc:HGNC:7714]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940;K03940	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0070469//respirasome;GO:0097060//synaptic membrane	"GO:0002020//protease binding;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0046872//metal ion binding;GO:0048038//quinone binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0015990//electron transport coupled proton transport;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000115289	4.465	5.341	5.11	5.597	4.404	6.137	84	101	71	78	70	84	PCGF1	polycomb group ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17615]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11487	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0035518//histone H2A monoubiquitination;GO:0036353//histone H2A-K119 monoubiquitination"	--
ENSG00000115290	0.167	0.222	0.16	0.151	0.231	0.159	6	8	2	4	7	5	GRB14	growth factor receptor bound protein 14 [Source:HGNC Symbol;Acc:HGNC:4565]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0030971//receptor tyrosine kinase binding	GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway	--
ENSG00000115295	16.369	15.795	15.979	12.741	12.101	15.088	1354	1295	969	791	845	945	CLIP4	CAP-Gly domain containing linker protein family member 4 [Source:HGNC Symbol;Acc:HGNC:26108]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035371//microtubule plus-end;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0051010//microtubule plus-end binding	GO:0031122//cytoplasmic microtubule organization	--
ENSG00000115297	0.022	0	0	0	0	0	1	0	0	0	0	0	TLX2	T cell leukemia homeobox 2 [Source:HGNC Symbol;Acc:HGNC:5057]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001707//mesoderm formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048484//enteric nervous system development;GO:0048513//animal organ development;GO:0050774//negative regulation of dendrite morphogenesis"	Homeobox
ENSG00000115306	45.201	47.635	44.473	34.202	38.324	38.901	7827	8121	5602	4187	5536	4493	SPTBN1	"spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]"	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008091//spectrin;GO:0014069//postsynaptic density;GO:0014731//spectrin-associated cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030673//axolemma;GO:0030863//cortical cytoskeleton;GO:0030864//cortical actin cytoskeleton;GO:0031430//M band;GO:0032437//cuticular plate;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0030506//ankyrin binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0051020//GTPase binding	GO:0000281//mitotic cytokinesis;GO:0007009//plasma membrane organization;GO:0007010//cytoskeleton organization;GO:0007154//cell communication;GO:0007182//common-partner SMAD protein phosphorylation;GO:0023052//signaling;GO:0030036//actin cytoskeleton organization;GO:0032743//positive regulation of interleukin-2 production;GO:0043001//Golgi to plasma membrane protein transport;GO:0050896//response to stimulus;GO:0051641//cellular localization;GO:0051693//actin filament capping;GO:0060390//regulation of SMAD protein signal transduction;GO:0071709//membrane assembly;GO:0072659//protein localization to plasma membrane;GO:1903076//regulation of protein localization to plasma membrane;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000115307	48.928	51.021	50.921	58.038	57	54.97	1486	1558	1143	1304	1461	1215	AUP1	AUP1 lipid droplet regulating VLDL assembly factor [Source:HGNC Symbol;Acc:HGNC:891]	-	-	-	-	GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0097027//ubiquitin-protein transferase activator activity	"GO:0009615//response to virus;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0034389//lipid droplet organization;GO:0050790//regulation of catalytic activity;GO:0061724//lipophagy;GO:0071712//ER-associated misfolded protein catabolic process;GO:0140042//lipid droplet formation;GO:1990044//protein localization to lipid droplet"	--
ENSG00000115310	141.598	137.429	123.683	116.36	118.76	116.862	6656	6573	4302	4041	4744	4015	RTN4	reticulon 4 [Source:HGNC Symbol;Acc:HGNC:14085]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K20720	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042995//cell projection;GO:0071782//endoplasmic reticulum tubular network;GO:0098826//endoplasmic reticulum tubular network membrane;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0001825//blastocyst formation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0006915//apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0007399//nervous system development;GO:0007413//axonal fasciculation;GO:0010634//positive regulation of epithelial cell migration;GO:0021801//cerebral cortex radial glia-guided migration;GO:0022009//central nervous system vasculogenesis;GO:0030308//negative regulation of cell growth;GO:0030334//regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0035022//positive regulation of Rac protein signal transduction;GO:0035441//cell migration involved in vasculogenesis;GO:0042981//regulation of apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0050821//protein stabilization;GO:0051292//nuclear pore complex assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051960//regulation of nervous system development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060907//positive regulation of macrophage cytokine production;GO:0061462//protein localization to lysosome;GO:0071456//cellular response to hypoxia;GO:0071786//endoplasmic reticulum tubular network organization;GO:0071787//endoplasmic reticulum tubular network formation;GO:0090156//cellular sphingolipid homeostasis;GO:0120078//cell adhesion involved in sprouting angiogenesis;GO:1902430//negative regulation of amyloid-beta formation;GO:1902624//positive regulation of neutrophil migration;GO:1905523//positive regulation of macrophage migration;GO:1905552//positive regulation of protein localization to endoplasmic reticulum;GO:1905580//positive regulation of ERBB3 signaling pathway;GO:1905653//positive regulation of artery morphogenesis;GO:1990809//endoplasmic reticulum tubular network membrane organization;GO:2000172//regulation of branching morphogenesis of a nerve;GO:2000347//positive regulation of hepatocyte proliferation;GO:2001213//negative regulation of vasculogenesis	--
ENSG00000115317	14.496	14.148	15.188	15.472	14.432	16.332	535.52	524.88	413.31	422.41	450.4	437.84	HTRA2	HtrA serine peptidase 2 [Source:HGNC Symbol;Acc:HGNC:14348]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Cell growth and death;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04210//Apoptosis;ko04215//Apoptosis - multiple species	K08669;K08669;K08669;K08669	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0035631//CD40 receptor complex;GO:1905370//serine-type endopeptidase complex	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding	GO:0006508//proteolysis;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process;GO:0007005//mitochondrion organization;GO:0007568//aging;GO:0007628//adult walking behavior;GO:0008344//adult locomotory behavior;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009635//response to herbicide;GO:0010822//positive regulation of mitochondrion organization;GO:0012501//programmed cell death;GO:0016540//protein autoprocessing;GO:0019742//pentacyclic triterpenoid metabolic process;GO:0030900//forebrain development;GO:0034599//cellular response to oxidative stress;GO:0034605//cellular response to heat;GO:0035458//cellular response to interferon-beta;GO:0040014//regulation of multicellular organism growth;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044257//cellular protein catabolic process;GO:0045786//negative regulation of cell cycle;GO:0048666//neuron development;GO:0060548//negative regulation of cell death;GO:0071300//cellular response to retinoic acid;GO:0071363//cellular response to growth factor stimulus;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:1901215//negative regulation of neuron death;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1904924//negative regulation of mitophagy in response to mitochondrial depolarization;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000115318	5.625	5.993	4.479	4.632	5.133	4.938	330.48	364.12	218.69	162.59	245.6	175.16	LOXL3	lysyl oxidase like 3 [Source:HGNC Symbol;Acc:HGNC:13869]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	"GO:0001968//fibronectin binding;GO:0004720//protein-lysine 6-oxidase activity;GO:0005044//scavenger receptor activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046872//metal ion binding"	"GO:0001837//epithelial to mesenchymal transition;GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0018057//peptidyl-lysine oxidation;GO:0021510//spinal cord development;GO:0030199//collagen fibril organization;GO:0030324//lung development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060021//roof of mouth development;GO:0061053//somite development;GO:1905590//fibronectin fibril organization;GO:2000329//negative regulation of T-helper 17 cell lineage commitment;GO:2001046//positive regulation of integrin-mediated signaling pathway"	--
ENSG00000115325	7.842	9.274	9.235	8.694	8.161	7.694	310	369	271	257	274	221	DOK1	docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction;GO:0035556//intracellular signal transduction;GO:0038145//macrophage colony-stimulating factor signaling pathway	--
ENSG00000115339	3.232	3.254	2.852	2.686	2.668	3.378	215	220	124	136	142	164	GALNT3	polypeptide N-acetylgalactosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:4125]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005509//calcium ion binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007283//spermatogenesis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016266//O-glycan processing;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine;GO:0034645//cellular macromolecule biosynthetic process	--
ENSG00000115350	6.46	6.646	5.296	9.256	6.554	6.946	147	152	89	156	126	115	POLE4	"DNA polymerase epsilon 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:18755]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair	K03506;K03506;K03506	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008622//epsilon DNA polymerase complex;GO:0140672//ATAC complex	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006261//DNA-dependent DNA replication;GO:0071897//DNA biosynthetic process	--
ENSG00000115353	0.02	0.03	0	0	0	0	2	3	0	0	0	0	TACR1	tachykinin receptor 1 [Source:HGNC Symbol;Acc:HGNC:11526]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04222;K04222	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0036126//sperm flagellum;GO:0044297//cell body;GO:0061827//sperm head;GO:0071944//cell periphery;GO:0097225//sperm midpiece	GO:0004930//G protein-coupled receptor activity;GO:0004995//tachykinin receptor activity;GO:0005515//protein binding;GO:0016496//substance P receptor activity	"GO:0002118//aggressive behavior;GO:0002526//acute inflammatory response;GO:0002687//positive regulation of leukocyte migration;GO:0003051//angiotensin-mediated drinking behavior;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007217//tachykinin receptor signaling pathway;GO:0007611//learning or memory;GO:0007616//long-term memory;GO:0008217//regulation of blood pressure;GO:0008306//associative learning;GO:0009408//response to heat;GO:0009582//detection of abiotic stimulus;GO:0009725//response to hormone;GO:0010193//response to ozone;GO:0010634//positive regulation of epithelial cell migration;GO:0010996//response to auditory stimulus;GO:0014070//response to organic cyclic compound;GO:0014910//regulation of smooth muscle cell migration;GO:0019233//sensory perception of pain;GO:0032224//positive regulation of synaptic transmission, cholinergic;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0035094//response to nicotine;GO:0035106//operant conditioning;GO:0035815//positive regulation of renal sodium excretion;GO:0042713//sperm ejaculation;GO:0042755//eating behavior;GO:0043117//positive regulation of vascular permeability;GO:0043278//response to morphine;GO:0045471//response to ethanol;GO:0045760//positive regulation of action potential;GO:0045777//positive regulation of blood pressure;GO:0045778//positive regulation of ossification;GO:0045907//positive regulation of vasoconstriction;GO:0046878//positive regulation of saliva secretion;GO:0046887//positive regulation of hormone secretion;GO:0048265//response to pain;GO:0048266//behavioral response to pain;GO:0048660//regulation of smooth muscle cell proliferation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051496//positive regulation of stress fiber assembly;GO:0051602//response to electrical stimulus;GO:0060083//smooth muscle contraction involved in micturition;GO:0070472//regulation of uterine smooth muscle contraction;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:1902093//positive regulation of flagellated sperm motility"	--
ENSG00000115355	3.678	2.637	1.703	1.672	1.832	2.646	424	263	154	116	214	161	CCDC88A	coiled-coil domain containing 88A [Source:HGNC Symbol;Acc:HGNC:25523]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0001965//G-protein alpha-subunit binding;GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0035091//phosphatidylinositol binding;GO:0042169//SH2 domain binding;GO:0042803//protein homodimerization activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0043422//protein kinase B binding;GO:0051959//dynein light intermediate chain binding	GO:0001932//regulation of protein phosphorylation;GO:0006260//DNA replication;GO:0006275//regulation of DNA replication;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0010975//regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0030030//cell projection organization;GO:0030032//lamellipodium assembly;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization;GO:0031929//TOR signaling;GO:0032147//activation of protein kinase activity;GO:0032148//activation of protein kinase B activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0042127//regulation of cell population proliferation;GO:0045724//positive regulation of cilium assembly;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0061024//membrane organization;GO:0072660//maintenance of protein location in plasma membrane;GO:1903566//positive regulation of protein localization to cilium	TF_bZIP
ENSG00000115361	0.422	0.381	0.156	0.155	0.499	0.474	22	20	6	6	22	18	ACADL	acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K00255;K00255;K00255;K00255	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane	"GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0016401//palmitoyl-CoA oxidase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding"	"GO:0001659//temperature homeostasis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0019254//carnitine metabolic process, CoA-linked;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0042413//carnitine catabolic process;GO:0042758//long-chain fatty acid catabolic process;GO:0044242//cellular lipid catabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0046322//negative regulation of fatty acid oxidation;GO:0090181//regulation of cholesterol metabolic process;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000115363	5.705	5.481	4.369	4.82	3.771	5.359	136	156	94	102	106	120	EVA1A	"eva-1 homolog A, regulator of programmed cell death [Source:HGNC Symbol;Acc:HGNC:25816]"	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0006914//autophagy;GO:0006915//apoptotic process	--
ENSG00000115364	15.832	14.607	13.269	14.583	13.706	17.748	1076	1013	688	703	802	798	MRPL19	mitochondrial ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:14052]	Genetic Information Processing	Translation	ko03010//Ribosome	K02884	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000115365	10.607	9.335	10.063	8.583	11.342	10.622	886	844	652	568	722	648	LANCL1	LanC like 1 [Source:HGNC Symbol;Acc:HGNC:6508]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K25210;K25210	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane	GO:0004364//glutathione transferase activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0043295//glutathione binding;GO:0046872//metal ion binding;GO:0050750//low-density lipoprotein particle receptor binding	GO:0005975//carbohydrate metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0043523//regulation of neuron apoptotic process;GO:1903203//regulation of oxidative stress-induced neuron death	--
ENSG00000115368	9.671	7.358	6.543	5.188	5.95	6.629	410	407	269	211	276	270	WDR75	WD repeat domain 75 [Source:HGNC Symbol;Acc:HGNC:25725]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14552	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:2000234//positive regulation of rRNA processing	--
ENSG00000115380	554.718	585.352	540.434	367.16	383.741	393.967	25747	26569	17950	12319	15045	12849	EFEMP1	EGF containing fibulin extracellular matrix protein 1 [Source:HGNC Symbol;Acc:HGNC:3218]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005006//epidermal growth factor-activated receptor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007601//visual perception;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0043010//camera-type eye development;GO:0048048//embryonic eye morphogenesis;GO:0048050//post-embryonic eye morphogenesis"	--
ENSG00000115386	0	0	0	0	0.074	0	0	0	0	0	1	0	REG1A	regenerating family member 1 alpha [Source:HGNC Symbol;Acc:HGNC:9951]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0008083//growth factor activity;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0042834//peptidoglycan binding;GO:0070492//oligosaccharide binding	GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0044278//cell wall disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000115392	6.216	5.229	6.531	4.623	4.791	6.177	241.82	194.83	180.26	119.29	159.97	168.68	FANCL	FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Replication and repair"	ko04120//Ubiquitin mediated proteolysis;ko03460//Fanconi anemia pathway	K10606;K10606	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle;GO:0043240//Fanconi anaemia nuclear complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007276//gamete generation;GO:0016567//protein ubiquitination;GO:0036297//interstrand cross-link repair;GO:0042127//regulation of cell population proliferation	--
ENSG00000115414	116.424	117.323	66.393	19.062	28.003	16.243	17161	17955	7438	2005	3606	1765	FN1	fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cell motility;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction;Infectious disease: bacterial	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction;ko05100//Bacterial invasion of epithelial cells	K05717;K05717;K05717;K05717;K05717;K05717;K05717;K05717;K05717;K05717;K05717;K05717	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0016324//apical plasma membrane;GO:0031012//extracellular matrix;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008022//protein C-terminus binding;GO:0008201//heparin binding;GO:0016504//peptidase activator activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0043394//proteoglycan binding;GO:0051087//chaperone binding;GO:0097718//disordered domain specific binding	"GO:0001525//angiogenesis;GO:0001932//regulation of protein phosphorylation;GO:0006953//acute-phase response;GO:0007044//cell-substrate junction assembly;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007161//calcium-independent cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0009611//response to wounding;GO:0010628//positive regulation of gene expression;GO:0010952//positive regulation of peptidase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0018149//peptide cross-linking;GO:0033622//integrin activation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035987//endodermal cell differentiation;GO:0042060//wound healing;GO:0045773//positive regulation of axon extension;GO:0048146//positive regulation of fibroblast proliferation;GO:0051702//biological process involved in interaction with symbiont;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0071635//negative regulation of transforming growth factor beta production;GO:0072378//blood coagulation, fibrin clot formation;GO:0150102//negative regulation of monocyte activation;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:1904237//positive regulation of substrate-dependent cell migration, cell attachment to substrate"	--
ENSG00000115415	21.205	21.929	18.595	17.485	15.676	17.347	1764.28	1843	1126	1050.18	1096	1028.24	STAT1	signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Development and regeneration;Endocrine system;Endocrine system;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Immune system;Cancer: overview;Cancer: specific types;Endocrine system;Immune disease	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05212//Pancreatic cancer;ko04917//Prolactin signaling pathway;ko05321//Inflammatory bowel disease"	K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220;K11220	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0070721//ISGF3 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0031730//CCR5 chemokine receptor binding;GO:0035035//histone acetyltransferase binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0045296//cadherin binding;GO:0051721//protein phosphatase 2A binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002230//positive regulation of defense response to virus by host;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007584//response to nutrient;GO:0008015//blood circulation;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0010742//macrophage derived foam cell differentiation;GO:0014070//response to organic cyclic compound;GO:0016525//negative regulation of angiogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0032727//positive regulation of interferon-alpha production;GO:0032869//cellular response to insulin stimulus;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034097//response to cytokine;GO:0035456//response to interferon-beta;GO:0035458//cellular response to interferon-beta;GO:0042127//regulation of cell population proliferation;GO:0042542//response to hydrogen peroxide;GO:0042981//regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043434//response to peptide hormone;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046725//negative regulation by virus of viral protein levels in host cell;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051591//response to cAMP;GO:0051607//defense response to virus;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0061326//renal tubule development;GO:0070106//interleukin-27-mediated signaling pathway;GO:0071345//cellular response to cytokine stimulus;GO:0071346//cellular response to interferon-gamma;GO:0071407//cellular response to organic cyclic compound;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation"	STAT
ENSG00000115419	21.977	18.229	19.728	23.216	21.195	32.045	2066.72	1687	1318	1542.82	1696	1987.76	GLS	glutaminase [Source:HGNC Symbol;Acc:HGNC:4331]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Nervous system;Nervous system;Cancer: overview;Amino acid metabolism;Excretory system;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko04724//Glutamatergic synapse;ko04727//GABAergic synapse;ko05230//Central carbon metabolism in cancer;ko00250//Alanine, aspartate and glutamate metabolism;ko04964//Proximal tubule bicarbonate reclamation;ko00220//Arginine biosynthesis;ko00470//D-Amino acid metabolism"	K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0045202//synapse	GO:0004359//glutaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0001967//suckling behavior;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006537//glutamate biosynthetic process;GO:0006541//glutamine metabolic process;GO:0006543//glutamine catabolic process;GO:0007268//chemical synaptic transmission;GO:0051289//protein homotetramerization;GO:0090461//glutamate homeostasis	--
ENSG00000115421	3.819	3.826	3.23	2.247	2.525	2.886	407	385	262	167	222	232	PAPOLG	poly(A) polymerase gamma [Source:HGNC Symbol;Acc:HGNC:14982]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14376	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation	--
ENSG00000115423	0.181	0.29	0.128	0.077	0.081	0.109	48	77	25	15	18	21	DNAH6	dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement;GO:0060285//cilium-dependent cell motility	--
ENSG00000115425	3.925	4.111	4.774	4.288	3.907	4.693	152	160	133	123	126	131	PECR	peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K07753	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol	GO:0005102//signaling receptor binding;GO:0016491//oxidoreductase activity;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0033306//phytol metabolic process	--
ENSG00000115446	19.56	22.824	25.922	24.739	25.535	24.989	482	551	466	438	523	440	UNC50	unc-50 inner nuclear membrane RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16046]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0034394//protein localization to cell surface	--
ENSG00000115457	42.978	46.726	22.856	24.432	24.264	15.666	948	1035	403	407	507	264	IGFBP2	insulin like growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:5471]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding	GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0007568//aging;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0010226//response to lithium ion;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032868//response to insulin;GO:0032870//cellular response to hormone stimulus;GO:0040008//regulation of growth;GO:0042104//positive regulation of activated T cell proliferation;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0048545//response to steroid hormone;GO:0051384//response to glucocorticoid;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000115459	6.043	5.382	6.316	5.608	4.617	5.776	232	220	195	174	190	201	ELMOD3	ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0060091//kinocilium	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000115461	269.25	272.182	277.229	249.495	298.385	219.921	34829	35404	26468	23916	32623	20679	IGFBP5	insulin like growth factor binding protein 5 [Source:HGNC Symbol;Acc:HGNC:5474]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016942//insulin-like growth factor binding protein complex;GO:0042567//insulin-like growth factor ternary complex	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding	GO:0001558//regulation of cell growth;GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0007568//aging;GO:0014912//negative regulation of smooth muscle cell migration;GO:0017148//negative regulation of translation;GO:0030336//negative regulation of cell migration;GO:0031069//hair follicle morphogenesis;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042593//glucose homeostasis;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0044342//type B pancreatic cell proliferation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045926//negative regulation of growth;GO:0048286//lung alveolus development;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051146//striated muscle cell differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0060056//mammary gland involution;GO:0060416//response to growth hormone;GO:0071320//cellular response to cAMP;GO:0071407//cellular response to organic cyclic compound;GO:1901862//negative regulation of muscle tissue development;GO:1904205//negative regulation of skeletal muscle hypertrophy;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration	--
ENSG00000115464	36.09	26.514	25.485	18.792	22.158	23.014	6342	3986	2969	2195	2926	2715	USP34	ubiquitin specific peptidase 34 [Source:HGNC Symbol;Acc:HGNC:20066]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0016579//protein deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000115468	2.002	2.239	1.42	3.807	4.239	3.293	78	83	40	98	123	82	EFHD1	EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0061891//calcium ion sensor activity	GO:0031175//neuron projection development;GO:1900069//regulation of cellular hyperosmotic salinity response	--
ENSG00000115474	51.218	44.273	40.669	35.169	46.207	43.345	2698	2390	1639	1402	1775	1608	KCNJ13	potassium inwardly rectifying channel subfamily J member 13 [Source:HGNC Symbol;Acc:HGNC:6259]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K05006	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000115484	55.584	56.908	50.849	51.91	47.453	50.124	2739	2819	1850	1895	1975	1796	CCT4	chaperonin containing TCP1 subunit 4 [Source:HGNC Symbol;Acc:HGNC:1617]	-	-	-	-	GO:0002199//zona pellucida receptor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0042470//melanosome;GO:0042995//cell projection;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0050821//protein stabilization;GO:0051973//positive regulation of telomerase activity;GO:0061077//chaperone-mediated protein folding;GO:0090666//scaRNA localization to Cajal body;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000115486	28.962	26.554	34.805	27.994	30.001	27.292	1633	1643.59	1338.79	1149.37	1358.46	1268.8	GGCX	gamma-glutamyl carboxylase [Source:HGNC Symbol;Acc:HGNC:4247]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K10106;K10106	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008488//gamma-glutamyl carboxylase activity;GO:0016829//lyase activity;GO:0019842//vitamin binding	GO:0006464//cellular protein modification process;GO:0007596//blood coagulation;GO:0017187//peptidyl-glutamic acid carboxylation	--
ENSG00000115488	0	0	0	0	0	0	0	0	0	0	0	0	NEU2	neuraminidase 2 [Source:HGNC Symbol;Acc:HGNC:7759]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K12357;K12357;K12357	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:1902494//catalytic complex	"GO:0004308//exo-alpha-sialidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052796//exo-alpha-(2->8)-sialidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006516//glycoprotein catabolic process;GO:0006629//lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0016042//lipid catabolic process;GO:0051692//cellular oligosaccharide catabolic process	--
ENSG00000115504	9.911	6.45	10.799	4.681	5.335	5.544	802	585	462	345	379	343	EHBP1	EH domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29144]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031941//filamentous actin	GO:0005515//protein binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0030036//actin cytoskeleton organization	--
ENSG00000115507	2.35	2.035	2.459	3.269	2.744	2.788	138	120	107	139	136	119	OTX1	orthodenticle homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8521]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09326	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:0022037//metencephalon development;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0042472//inner ear morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048852//diencephalon morphogenesis"	TF_Otx
ENSG00000115514	10.107	11.038	10.14	7.516	7.862	8.544	293	340	225	168	188	189	TXNDC9	thioredoxin domain containing 9 [Source:HGNC Symbol;Acc:HGNC:24110]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000226//microtubule cytoskeleton organization;GO:0006457//protein folding;GO:0008150//biological_process	--
ENSG00000115520	10.591	9.681	11.23	9.607	8.106	9.757	447	409	319	241	300	311	COQ10B	coenzyme Q10B [Source:HGNC Symbol;Acc:HGNC:25819]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0048039//ubiquinone binding	GO:0006744//ubiquinone biosynthetic process;GO:0045333//cellular respiration	--
ENSG00000115523	0	0	0	0	0.073	0	0	0	0	0	1	0	GNLY	granulysin [Source:HGNC Symbol;Acc:HGNC:4414]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0044194//cytolytic granule;GO:0097013//phagocytic vesicle lumen	GO:0005515//protein binding	GO:0006968//cellular defense response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050832//defense response to fungus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000115524	90.274	80.883	83.964	56.027	66.481	86.57	6634	5945	4497	3194	4111	4103	SF3B1	splicing factor 3b subunit 1 [Source:HGNC Symbol;Acc:HGNC:10768]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12828	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0034693//U11/U12 snRNP;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0110016//B-WICH complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:1990935//splicing factor binding	"GO:0000245//spliceosomal complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006338//chromatin remodeling;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0035066//positive regulation of histone acetylation;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III"	--
ENSG00000115525	17.808	16.555	14.853	14.529	14.474	15.038	862	818	547	524	581	553	ST3GAL5	"ST3 beta-galactoside alpha-2,3-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:10872]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03370;K03370	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0004513//neolactotetraosylceramide alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047291//lactosylceramide alpha-2,3-sialyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0097503//sialylation	--
ENSG00000115526	7.497	8.535	7.19	7.933	10.041	8.415	420	443	284	344	361	336	CHST10	carbohydrate sulfotransferase 10 [Source:HGNC Symbol;Acc:HGNC:19650]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K09674;K09674	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0008146//sulfotransferase activity;GO:0016232//HNK-1 sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0007155//cell adhesion;GO:0007612//learning;GO:0007616//long-term memory;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process	--
ENSG00000115539	10.497	10.744	10.125	9.092	8.136	7.596	226	228	161	145	148	119	PDCL3	phosducin like 3 [Source:HGNC Symbol;Acc:HGNC:28860]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0097356//perinucleolar compartment	GO:0005515//protein binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0044183//protein folding chaperone	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006915//apoptotic process;GO:0010628//positive regulation of gene expression;GO:0030036//actin cytoskeleton organization;GO:0045766//positive regulation of angiogenesis;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1903645//negative regulation of chaperone-mediated protein folding;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000115540	9.172	9.895	9.854	6.164	7.385	8.53	477.38	471.66	325.49	248.46	336.8	295	MOB4	"MOB family member 4, phocein [Source:HGNC Symbol;Acc:HGNC:17261]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000115541	49.149	51.713	68.655	63.076	48.27	59.299	562.35	595.6	582.94	534.03	466.41	497	HSPE1	heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0001649//osteoblast differentiation;GO:0006457//protein folding;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006986//response to unfolded protein;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000115548	14.046	12.588	10.032	9.392	10.411	7.999	1390	1255	736	690	870	577	KDM3A	lysine demethylase 3A [Source:HGNC Symbol;Acc:HGNC:20815]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K15601	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0051213//dioxygenase activity;GO:0140683//histone H3-di/monomethyl-lysine-9 demethylase activity	"GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007290//spermatid nucleus elongation;GO:0009755//hormone-mediated signaling pathway;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0030521//androgen receptor signaling pathway;GO:0033169//histone H3-K9 demethylation;GO:0036123//histone H3-K9 dimethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046293//formaldehyde biosynthetic process;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000036//regulation of stem cell population maintenance;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000115556	0.041	0.019	0.076	0	0.022	0.024	2.66	1.23	3.6	0	1.21	1.05	PLCD4	phospholipase C delta 4 [Source:HGNC Symbol;Acc:HGNC:9062]	Metabolism;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05131//Shigellosis;ko04919//Thyroid hormone signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K05857;K05857;K05857;K05857;K05857;K05857;K05857	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0001965//G-protein alpha-subunit binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007340//acrosome reaction;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000115561	23.328	25.841	23.447	25.241	23.503	23.761	1145	1199.21	880	920	989.94	814.26	CHMP3	charged multivesicular body protein 3 [Source:HGNC Symbol;Acc:HGNC:29865]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12193;K12193	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0031210//phosphatidylcholine binding;GO:0042802//identical protein binding;GO:1990381//ubiquitin-specific protease binding	GO:0001778//plasma membrane repair;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0031468//nuclear membrane reassembly;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0044790//negative regulation by host of viral release from host cell;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0051258//protein polymerization;GO:0051301//cell division;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:2000641//regulation of early endosome to late endosome transport	--
ENSG00000115568	4.284	4.501	4.044	4.762	5.363	4.483	595.34	621.77	460.4	488	617.79	477.95	ZNF142	zinc finger protein 142 [Source:HGNC Symbol;Acc:HGNC:12927]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000115590	0	0.121	0	0	0	0	0	2	0	0	0	0	IL1R2	interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Cancer: overview;Infectious disease: viral;Infectious disease: parasitic;Immune system;Cardiovascular disease;Cancer: specific types	ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko05418//Fluid shear stress and atherosclerosis;ko05215//Prostate cancer	K04387;K04387;K04387;K04387;K04387;K04387;K04387	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004908//interleukin-1 receptor activity;GO:0004910//interleukin-1, type II, blocking receptor activity;GO:0005515//protein binding;GO:0019966//interleukin-1 binding"	GO:0006955//immune response;GO:0010955//negative regulation of protein processing;GO:0019221//cytokine-mediated signaling pathway;GO:0032690//negative regulation of interleukin-1 alpha production;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway	--
ENSG00000115592	0.021	0.065	0	0.057	0.025	0	1	3	0	2	1	0	PRKAG3	protein kinase AMP-activated non-catalytic subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:9387]	Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04921//Oxytocin signaling pathway;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031588//nucleotide-activated protein kinase complex	GO:0000166//nucleotide binding;GO:0004679//AMP-activated protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0032559//adenyl ribonucleotide binding	GO:0005978//glycogen biosynthetic process;GO:0006096//glycolytic process;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:0016310//phosphorylation;GO:0031669//cellular response to nutrient levels;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0050790//regulation of catalytic activity;GO:0071900//regulation of protein serine/threonine kinase activity	--
ENSG00000115593	0.099	0.089	0.03	0.045	0.143	0.276	9	6	2	3	11	12	SMYD1	SET and MYND domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20986]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11426;K11426	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding	"GO:0006338//chromatin remodeling;GO:0007507//heart development;GO:0010831//positive regulation of myotube differentiation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0035914//skeletal muscle cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000115594	0.373	0.491	0.262	0.892	0.407	0.599	33	44	17	43	37	44	IL1R1	interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: parasitic;Immune system;Cardiovascular disease;Development and regeneration;Immune system;Sensory system	ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko04750//Inflammatory mediator regulation of TRP channels	K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386;K04386	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0002020//protease binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0004908//interleukin-1 receptor activity;GO:0004909//interleukin-1, type I, activating receptor activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019966//interleukin-1 binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0050727//regulation of inflammatory response;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0071345//cellular response to cytokine stimulus;GO:2000391//positive regulation of neutrophil extravasation;GO:2000556//positive regulation of T-helper 1 cell cytokine production;GO:2000661//positive regulation of interleukin-1-mediated signaling pathway	--
ENSG00000115596	0	0	0	0.038	0.066	0.077	0	0	0	1	2	2	WNT6	Wnt family member 6 [Source:HGNC Symbol;Acc:HGNC:12785]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445;K00445	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity	"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0007275//multicellular organism development;GO:0009798//axis specification;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060070//canonical Wnt signaling pathway;GO:0060684//epithelial-mesenchymal cell signaling;GO:0061303//cornea development in camera-type eye;GO:0070172//positive regulation of tooth mineralization;GO:0071300//cellular response to retinoic acid;GO:0072079//nephron tubule formation;GO:0072080//nephron tubule development"	--
ENSG00000115598	0	0	0	0	0	0	0	0	0	0	0	0	IL1RL2	interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05172	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003953//NAD+ nucleosidase activity;GO:0004908//interleukin-1 receptor activity;GO:0004909//interleukin-1, type I, activating receptor activity;GO:0016787//hydrolase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0045582//positive regulation of T cell differentiation;GO:0050727//regulation of inflammatory response;GO:0070498//interleukin-1-mediated signaling pathway	--
ENSG00000115602	0	0	0	0	0	0	0	0	0	0	0	0	IL1RL1	interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05171	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0002113//interleukin-33 binding;GO:0002114//interleukin-33 receptor activity;GO:0003953//NAD+ nucleosidase activity;GO:0004896//cytokine receptor activity;GO:0004908//interleukin-1 receptor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0002826//negative regulation of T-helper 1 type immune response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032689//negative regulation of interferon-gamma production;GO:0032722//positive regulation of chemokine production;GO:0032754//positive regulation of interleukin-5 production;GO:0038172//interleukin-33-mediated signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0050729//positive regulation of inflammatory response	--
ENSG00000115604	0	0.027	0.081	0.042	0.065	0	0	2	4	2	2	0	IL18R1	interleukin 18 receptor 1 [Source:HGNC Symbol;Acc:HGNC:5988]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05321//Inflammatory bowel disease	K05173;K05173;K05173;K05173	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045092//interleukin-18 receptor complex	"GO:0003953//NAD+ nucleosidase activity;GO:0004908//interleukin-1 receptor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0038023//signaling receptor activity;GO:0042007//interleukin-18 binding;GO:0042008//interleukin-18 receptor activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0030101//natural killer cell activation;GO:0032729//positive regulation of interferon-gamma production;GO:0035655//interleukin-18-mediated signaling pathway;GO:0045063//T-helper 1 cell differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000556//positive regulation of T-helper 1 cell cytokine production	--
ENSG00000115607	0	0	0	0	0	0	0	0	0	0	0	0	IL18RAP	interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signaling molecules and interaction;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05321//Inflammatory bowel disease	K05174;K05174;K05174	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045092//interleukin-18 receptor complex	"GO:0003953//NAD+ nucleosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042008//interleukin-18 receptor activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0035655//interleukin-18-mediated signaling pathway;GO:0042119//neutrophil activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070301//cellular response to hydrogen peroxide;GO:0071345//cellular response to cytokine stimulus;GO:0071351//cellular response to interleukin-18	--
ENSG00000115616	0.017	0.069	0	0.163	0.122	0.106	2	8	0	14	12	9	SLC9A2	solute carrier family 9 member A2 [Source:HGNC Symbol;Acc:HGNC:11072]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0008104//protein localization;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000115641	6.434	6.825	4.988	2.979	3.037	2.419	197	218	117	69	79	53	FHL2	four and a half LIM domains 2 [Source:HGNC Symbol;Acc:HGNC:3703]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K14380	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0030018//Z disc	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042802//identical protein binding;GO:0043425//bHLH transcription factor binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009725//response to hormone;GO:0043066//negative regulation of apoptotic process;GO:0055014//atrial cardiac muscle cell development;GO:0055015//ventricular cardiac muscle cell development;GO:0060347//heart trabecula formation;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade	--
ENSG00000115648	2.755	3.421	3.476	4.936	4.142	5.017	124	144	114	155	150	161	MLPH	melanophilin [Source:HGNC Symbol;Acc:HGNC:29643]	-	-	-	-	GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0030864//cortical actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0032402//melanosome transport	--
ENSG00000115649	18.415	18.768	20.946	25.222	21.461	21.161	759	771	633	757	753	638	CNPPD1	cyclin Pas1/PHO80 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25220]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000115652	26.172	26.023	25.51	20.494	21.761	21.006	1031	1040	741	589	720	604	UXS1	UDP-glucuronate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:17729]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K08678;K08678	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome;GO:1902494//catalytic complex	GO:0003824//catalytic activity;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0048040//UDP-glucuronate decarboxylase activity;GO:0070403//NAD+ binding	GO:0033320//UDP-D-xylose biosynthetic process;GO:0042732//D-xylose metabolic process	--
ENSG00000115657	11.005	11.008	10.644	12.417	14.538	11.355	676.85	675.39	483.88	557.33	755.74	510.36	ABCB6	ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05661	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0033162//melanosome membrane;GO:0036020//endolysosome membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015439//ABC-type heme transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0020037//heme binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046906//tetrapyrrole binding;GO:0140359//ABC-type transporter activity	GO:0006778//porphyrin-containing compound metabolic process;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006878//cellular copper ion homeostasis;GO:0006879//cellular iron ion homeostasis;GO:0007420//brain development;GO:0015886//heme transport;GO:0033013//tetrapyrrole metabolic process;GO:0035351//heme transmembrane transport;GO:0042168//heme metabolic process;GO:0043588//skin development;GO:0055085//transmembrane transport;GO:0098849//cellular detoxification of cadmium ion;GO:1903232//melanosome assembly	--
ENSG00000115661	12.304	14.738	14.745	12.857	13.709	14.508	416.7	443.09	327.81	306.04	365.94	307.34	STK16	serine/threonine kinase 16 [Source:HGNC Symbol;Acc:HGNC:11394]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000115665	0	0	0	0	0	0	0	0	0	0	0	0	SLC5A7	solute carrier family 5 member 7 [Source:HGNC Symbol;Acc:HGNC:14025]	Organismal Systems;Human Diseases	Nervous system;Cancer: overview	ko04725//Cholinergic synapse;ko05231//Choline metabolism in cancer	K14387;K14387	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse	GO:0005307//choline:sodium symporter activity;GO:0015220//choline transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0033265//choline binding	"GO:0001701//in utero embryonic development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006836//neurotransmitter transport;GO:0007271//synaptic transmission, cholinergic;GO:0007274//neuromuscular synaptic transmission;GO:0008292//acetylcholine biosynthetic process;GO:0015871//choline transport;GO:0042136//neurotransmitter biosynthetic process;GO:0055085//transmembrane transport"	--
ENSG00000115677	207.193	206.51	208.539	172.529	181.791	179.422	19660	19483	13383	12055	14378	11979	HDLBP	high density lipoprotein binding protein [Source:HGNC Symbol;Acc:HGNC:4857]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005886//plasma membrane;GO:0034364//high-density lipoprotein particle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0045296//cadherin binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process	--
ENSG00000115685	29.721	33.08	28.832	28.529	24.292	31.485	751	880	568	572	532	564	PPP1R7	protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0030234//enzyme regulator activity	GO:0035307//positive regulation of protein dephosphorylation;GO:0050790//regulation of catalytic activity;GO:0061588//calcium activated phospholipid scrambling	--
ENSG00000115687	2.44	1.502	1.589	2.09	1.695	1.93	165	146	114	110	139	121	PASK	PAS domain containing serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:17270]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035091//phosphatidylinositol binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043576//regulation of respiratory gaseous exchange;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0045727//positive regulation of translation;GO:0046777//protein autophosphorylation;GO:0070092//regulation of glucagon secretion;GO:0097009//energy homeostasis	--
ENSG00000115694	51.816	53.842	60.54	55.217	51.564	54.763	1640.11	1633.27	1294.32	1285.05	1504.66	1223.09	STK25	serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0036481//intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:0042542//response to hydrogen peroxide;GO:0046777//protein autophosphorylation;GO:0050772//positive regulation of axonogenesis;GO:0051645//Golgi localization;GO:0051683//establishment of Golgi localization;GO:0090168//Golgi reassembly	--
ENSG00000115705	0.009	0	0	0	0.014	0	1	0	0	0	1	0	TPO	thyroid peroxidase [Source:HGNC Symbol;Acc:HGNC:12015]	Metabolism;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Immune disease;Endocrine system;Amino acid metabolism	ko01100//Metabolic pathways;ko05320//Autoimmune thyroid disease;ko04918//Thyroid hormone synthesis;ko00350//Tyrosine metabolism	K00431;K00431;K00431;K00431	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004447//iodide peroxidase activity;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0006590//thyroid hormone generation;GO:0006979//response to oxidative stress;GO:0035162//embryonic hemopoiesis;GO:0042446//hormone biosynthetic process;GO:0042744//hydrogen peroxide catabolic process;GO:0071704//organic substance metabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000115718	0.505	0.473	0.307	0	0.161	0.125	11	9	7	0	5	3	PROC	"protein C, inactivator of coagulation factors Va and VIIIa [Source:HGNC Symbol;Acc:HGNC:9451]"	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01344	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030195//negative regulation of blood coagulation;GO:0043066//negative regulation of apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0050819//negative regulation of coagulation;GO:1903142//positive regulation of establishment of endothelial barrier	--
ENSG00000115738	35.313	29.66	38.845	27.886	27.12	29.241	959	757	776	534	599	574	ID2	inhibitor of DNA binding 2 [Source:HGNC Symbol;Acc:HGNC:5361]	Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Cellular community - eukaryotes;Signal transduction	ko05202//Transcriptional misregulation in cancer;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K17693;K17693;K17693;K17693	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003166//bundle of His development;GO:0007507//heart development;GO:0007623//circadian rhythm;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0019216//regulation of lipid metabolic process;GO:0021772//olfactory bulb development;GO:0030154//cell differentiation;GO:0032922//circadian regulation of gene expression;GO:0033598//mammary gland epithelial cell proliferation;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043353//enucleate erythrocyte differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045475//locomotor rhythm;GO:0045578//negative regulation of B cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045664//regulation of neuron differentiation;GO:0045777//positive regulation of blood pressure;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0048557//embryonic digestive tract morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048663//neuron fate commitment;GO:0048711//positive regulation of astrocyte differentiation;GO:0051148//negative regulation of muscle cell differentiation;GO:0060749//mammary gland alveolus development;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0061031//endodermal digestive tract morphogenesis;GO:0071931//positive regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0090398//cellular senescence;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000177//regulation of neural precursor cell proliferation"	bHLH
ENSG00000115750	3.72	3.359	4.06	2.449	2.393	2.189	167	157	124	76	89	70	TAF1B	"TATA-box binding protein associated factor, RNA polymerase I subunit B [Source:HGNC Symbol;Acc:HGNC:11533]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005668//RNA polymerase transcription factor SL1 complex;GO:0005730//nucleolus;GO:0070860//RNA polymerase I core factor complex	GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0017025//TBP-class protein binding;GO:0046872//metal ion binding	"GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006351//transcription, DNA-templated;GO:0006360//transcription by RNA polymerase I;GO:0042790//nucleolar large rRNA transcription by RNA polymerase I"	--
ENSG00000115756	8.132	9.487	6.664	10.974	9.877	8.115	293	352	178	293	298	214	HPCAL1	hippocalcin like 1 [Source:HGNC Symbol;Acc:HGNC:5145]	-	-	-	-	GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000115758	62.873	69.591	66.93	73.793	68.297	60.243	2954	3249	2318	2563	2751	2012	ODC1	ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00330//Arginine and proline metabolism	K01581;K01581;K01581	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004586//ornithine decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0042803//protein homodimerization activity	GO:0001822//kidney development;GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0008284//positive regulation of cell population proliferation;GO:0009615//response to virus;GO:0033387//putrescine biosynthetic process from ornithine;GO:0042176//regulation of protein catabolic process	--
ENSG00000115760	7.692	5.894	5.268	4.427	4.448	7.165	1869	1458	1114	650	1037	928	BIRC6	baculoviral IAP repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:13516]	Genetic Information Processing;Cellular Processes	"Folding, sorting and degradation;Cell growth and death"	ko04120//Ubiquitin mediated proteolysis;ko04215//Apoptosis - multiple species	K10586;K10586	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0090543//Flemming body	GO:0004842//ubiquitin-protein transferase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030414//peptidase inhibitor activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0001890//placenta development;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0016567//protein ubiquitination;GO:0032268//regulation of cellular protein metabolic process;GO:0032465//regulation of cytokinesis;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0051301//cell division;GO:0052548//regulation of endopeptidase activity;GO:0060711//labyrinthine layer development;GO:0060712//spongiotrophoblast layer development;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000115761	5.187	6.579	5.91	5.042	5.219	5.361	330	401	267	229	270	237	NOL10	nucleolar protein 10 [Source:HGNC Symbol;Acc:HGNC:25862]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000115762	42.944	44.241	48.923	49.397	48.981	52.76	3334	3432	2788	2851	3200	2965	PLEKHB2	pleckstrin homology domain containing B2 [Source:HGNC Symbol;Acc:HGNC:19236]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055038//recycling endosome membrane	"GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding"	GO:0045595//regulation of cell differentiation	--
ENSG00000115806	54.18	50.816	51.948	47.272	50.11	54.425	2515	2353	1730	1617	1963	1866	GORASP2	golgi reassembly stacking protein 2 [Source:HGNC Symbol;Acc:HGNC:17500]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane	GO:0005515//protein binding	GO:0006996//organelle organization;GO:0007030//Golgi organization;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0034976//response to endoplasmic reticulum stress;GO:0061951//establishment of protein localization to plasma membrane;GO:0070925//organelle assembly	--
ENSG00000115808	4.451	3.689	3.291	3.11	3.814	4.048	1011	681	503	446	594	532	STRN	striatin [Source:HGNC Symbol;Acc:HGNC:11424]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K17608	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0090443//FAR/SIN/STRIPAK complex	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0030331//estrogen receptor binding;GO:0044877//protein-containing complex binding;GO:0051721//protein phosphatase 2A binding;GO:0070016//armadillo repeat domain binding	GO:0007626//locomotory behavior;GO:0008285//negative regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0016358//dendrite development;GO:0070830//bicellular tight junction assembly	--
ENSG00000115816	8.919	6.866	6.223	5.738	5.594	6.297	619	479	319	295	328	318	CEBPZ	CCAAT enhancer binding protein zeta [Source:HGNC Symbol;Acc:HGNC:24218]	-	-	-	-	GO:0005634//nucleus;GO:0016602//CCAAT-binding factor complex	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding	GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000115825	7.79	6.947	6.792	5.301	4.987	6.786	993	770	523	419	538	571	PRKD3	protein kinase D3 [Source:HGNC Symbol;Acc:HGNC:9408]	Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Endocrine system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04015//Rap1 signaling pathway;ko04925//Aldosterone synthesis and secretion	K06070;K06070;K06070	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0089700//protein kinase D signaling	--
ENSG00000115827	4.966	4.49	4.484	3.243	4.105	3.751	482	399	289	233	337	314	DCAF17	DDB1 and CUL4 associated factor 17 [Source:HGNC Symbol;Acc:HGNC:25784]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000115828	3.284	3.078	1.862	2.265	1.967	3.016	113	108	48	54	58	69	QPCT	glutaminyl-peptide cyclotransferase [Source:HGNC Symbol;Acc:HGNC:9753]	-	-	-	-	GO:0005576//extracellular region;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016603//glutaminyl-peptide cyclotransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	"GO:0006464//cellular protein modification process;GO:0017186//peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase"	--
ENSG00000115839	20.722	19.391	18.493	14.406	16.393	18.946	1867	1688	1206	986	1193	1222	RAB3GAP1	RAB3 GTPase activating protein catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:17063]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0071782//endoplasmic reticulum tubular network;GO:0098794//postsynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007420//brain development;GO:0021854//hypothalamus development;GO:0034389//lipid droplet organization;GO:0043010//camera-type eye development;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0060079//excitatory postsynaptic potential;GO:0060325//face morphogenesis;GO:0061646//positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:1903061//positive regulation of protein lipidation;GO:1903233//regulation of calcium ion-dependent exocytosis of neurotransmitter;GO:1903373//positive regulation of endoplasmic reticulum tubular network organization;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000115840	6.843	6.312	6.964	6.496	6.681	8.297	436	410	340	333	366	388	SLC25A12	solute carrier family 25 member 12 [Source:HGNC Symbol;Acc:HGNC:10982]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015172//acidic amino acid transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006094//gluconeogenesis;GO:0006537//glutamate biosynthetic process;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0009066//aspartate family amino acid metabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0015810//aspartate transmembrane transport;GO:0015813//L-glutamate transmembrane transport;GO:0031643//positive regulation of myelination;GO:0043490//malate-aspartate shuttle;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0070778//L-aspartate transmembrane transport;GO:1904024//negative regulation of glucose catabolic process to lactate via pyruvate;GO:2001171//positive regulation of ATP biosynthetic process	--
ENSG00000115841	1.858	1.698	1.358	1.322	1.444	1.576	74	61	40	32	40	41	RMDN2	regulator of microtubule dynamics 2 [Source:HGNC Symbol;Acc:HGNC:26567]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding	-	--
ENSG00000115844	0	0	0	0	0	0	0	0	0	0	0	0	DLX2	distal-less homeobox 2 [Source:HGNC Symbol;Acc:HGNC:2915]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0009954//proximal/distal pattern formation;GO:0021544//subpallium development;GO:0021766//hippocampus development;GO:0021772//olfactory bulb development;GO:0021879//forebrain neuron differentiation;GO:0021892//cerebral cortex GABAergic interneuron differentiation;GO:0021893//cerebral cortex GABAergic interneuron fate commitment;GO:0030154//cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045597//positive regulation of cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0048755//branching morphogenesis of a nerve;GO:0051216//cartilage development;GO:1902871//positive regulation of amacrine cell differentiation"	Homeobox
ENSG00000115850	0.041	0	0.021	0	0	0	3	0	2	0	0	0	LCT	lactase [Source:HGNC Symbol;Acc:HGNC:6530]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04973//Carbohydrate digestion and absorption;ko00052//Galactose metabolism	K01229;K01229;K01229	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0098591//external side of apical plasma membrane	"GO:0000016//lactase activity;GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0017042//glycosylceramidase activity;GO:0042803//protein homodimerization activity"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000115866	21.121	21.038	16.971	17.823	20.291	21.918	1166	1041	775	725	823	805	DARS1	aspartyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:2678]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K22503	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004046//aminoacylase activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004815//aspartate-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006422//aspartyl-tRNA aminoacylation;GO:0065003//protein-containing complex assembly	--
ENSG00000115875	22.268	20.494	22.327	19.016	23.639	24.28	794	747	606	515	658	667	SRSF7	serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789]	Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Transcription	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12896;K12896;K12896	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0051028//mRNA transport;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000115884	1.201	1.315	1.687	1.075	1.521	1.232	74	86	41	52	58	39	SDC1	syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signaling molecules and interaction;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: parasitic	ko05205//Proteoglycans in cancer;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04512//ECM-receptor interaction;ko05144//Malaria	K06257;K06257;K06257;K06257;K06257	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding	GO:0001657//ureteric bud development;GO:0006954//inflammatory response;GO:0009636//response to toxic substance;GO:0010033//response to organic substance;GO:0016477//cell migration;GO:0042060//wound healing;GO:0042476//odontogenesis;GO:0042542//response to hydrogen peroxide;GO:0048627//myoblast development;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0051592//response to calcium ion;GO:0055002//striated muscle cell development;GO:0060009//Sertoli cell development;GO:0060070//canonical Wnt signaling pathway;GO:1903543//positive regulation of exosomal secretion;GO:1903553//positive regulation of extracellular exosome assembly	--
ENSG00000115896	4.441	3.302	3.66	3.378	3.546	4.327	436	299	286	268	305	302	PLCL1	phospholipase C like 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:9063]	Organismal Systems	Nervous system	ko04727//GABAergic synapse	K15375	GO:0005737//cytoplasm;GO:0005886//plasma membrane	"GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0050811//GABA receptor binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	"GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0016042//lipid catabolic process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900122//positive regulation of receptor binding"	--
ENSG00000115902	4.675	5.221	5.37	5.457	5.007	6.574	384	388	309	312	333	329	SLC1A4	solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942]	-	-	-	-	GO:0005813//centrosome;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005254//chloride channel activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015195//L-threonine transmembrane transporter activity;GO:0015293//symporter activity;GO:0034590//L-hydroxyproline transmembrane transporter activity	"GO:0006865//amino acid transport;GO:0006868//glutamine transport;GO:0015698//inorganic anion transport;GO:0015808//L-alanine transport;GO:0015811//L-cystine transport;GO:0015813//L-glutamate transmembrane transport;GO:0015824//proline transport;GO:0015825//L-serine transport;GO:0015826//threonine transport;GO:0034589//hydroxyproline transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035524//proline transmembrane transport;GO:0050890//cognition;GO:0098718//serine import across plasma membrane;GO:0140009//L-aspartate import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903812//L-serine import across plasma membrane;GO:1904273//L-alanine import across plasma membrane"	--
ENSG00000115904	10.122	6.657	6.607	4.945	6.867	7.049	1188	776	568	437	698	590	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:11187]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Cell motility;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Substance dependence;Immune system;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Immune system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04660//T cell receptor signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko05213//Endometrial cancer"	K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099;K03099	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:1905360//GTPase complex	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0046982//protein heterodimerization activity	GO:0001782//B cell homeostasis;GO:0001942//hair follicle development;GO:0002260//lymphocyte homeostasis;GO:0003007//heart morphogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0003344//pericardium morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007296//vitellogenesis;GO:0007411//axon guidance;GO:0019221//cytokine-mediated signaling pathway;GO:0033081//regulation of T cell differentiation in thymus;GO:0035264//multicellular organism growth;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042129//regulation of T cell proliferation;GO:0043405//regulation of MAP kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0050790//regulation of catalytic activity;GO:0050900//leukocyte migration;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0060021//roof of mouth development;GO:0061029//eyelid development in camera-type eye;GO:0061384//heart trabecula morphogenesis;GO:1904693//midbrain morphogenesis;GO:2000973//regulation of pro-B cell differentiation	--
ENSG00000115919	0.153	0.127	0.262	0.338	0.375	1.118	5	5	8	9	8	17	KYNU	kynureninase [Source:HGNC Symbol;Acc:HGNC:6469]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K01556;K01556	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030170//pyridoxal phosphate binding;GO:0030429//kynureninase activity;GO:0042803//protein homodimerization activity;GO:0061981//3-hydroxykynureninase activity	GO:0006569//tryptophan catabolic process;GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0019805//quinolinate biosynthetic process;GO:0034341//response to interferon-gamma;GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0034516//response to vitamin B6;GO:0043420//anthranilate metabolic process;GO:0097053//L-kynurenine catabolic process	--
ENSG00000115935	11.99	11.634	8.819	7.785	7.33	7.611	955	902	546	455	517	426	WIPF1	WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736]	Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko04144//Endocytosis;ko05135//Yersinia infection	K19475;K19475;K19475	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0017124//SH3 domain binding	GO:0008154//actin polymerization or depolymerization;GO:0030029//actin filament-based process;GO:0030048//actin filament-based movement;GO:0051707//response to other organism;GO:0065003//protein-containing complex assembly	--
ENSG00000115942	3.71	3.497	3.38	2.444	2.954	3.724	330	289	222	161	222	241	ORC2	origin recognition complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:8488]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02604	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0000808//origin recognition complex;GO:0000939//inner kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005813//centrosome;GO:0016020//membrane"	GO:0003688//DNA replication origin binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006270//DNA replication initiation	--
ENSG00000115944	39.365	41.417	49.289	46.288	42.131	41.461	1884	1902	1565	1588	1607	1415	COX7A2L	cytochrome c oxidase subunit 7A2 like [Source:HGNC Symbol;Acc:HGNC:2289]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0004129//cytochrome-c oxidase activity;GO:0009055//electron transfer activity	"GO:0002082//regulation of oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0097250//mitochondrial respirasome assembly;GO:1902600//proton transmembrane transport"	--
ENSG00000115946	6.342	4.427	5.183	4.79	5.167	5.701	294.93	206.93	178	165	203	192.89	PNO1	partner of NOB1 homolog [Source:HGNC Symbol;Acc:HGNC:32790]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000115947	5.844	8.782	4.45	7.961	5.584	6.076	583.49	523.73	376.66	334.2	384.44	333.75	ORC4	origin recognition complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:8490]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02606	"GO:0000781//chromosome, telomeric region;GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005730//nucleolus;GO:0005829//cytosol"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003688//DNA replication origin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0006260//DNA replication;GO:0006270//DNA replication initiation	--
ENSG00000115956	0	0.017	0	0	0.165	0.096	0	1	0	0	8	4	PLEK	pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane	"GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0002244//hematopoietic progenitor cell differentiation;GO:0002576//platelet degranulation;GO:0006904//vesicle docking involved in exocytosis;GO:0007229//integrin-mediated signaling pathway;GO:0010572//positive regulation of platelet activation;GO:0010920//negative regulation of inositol phosphate biosynthetic process;GO:0010925//positive regulation of inositol-polyphosphate 5-phosphatase activity;GO:0030030//cell projection organization;GO:0030836//positive regulation of actin filament depolymerization;GO:0030845//phospholipase C-inhibiting G protein-coupled receptor signaling pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0031529//ruffle organization;GO:0031532//actin cytoskeleton reorganization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0033625//positive regulation of integrin activation;GO:0035556//intracellular signal transduction;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0046488//phosphatidylinositol metabolic process;GO:0050849//negative regulation of calcium-mediated signaling;GO:0060305//regulation of cell diameter;GO:0070493//thrombin-activated receptor signaling pathway;GO:0070527//platelet aggregation;GO:0070528//protein kinase C signaling;GO:0070560//protein secretion by platelet	Others
ENSG00000115963	10.096	9.388	6.447	7.751	8.245	9.602	573	510	272	326	396	353	RND3	Rho family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:671]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization	--
ENSG00000115966	17.17	12.802	12.934	9.901	12.055	13.252	1207	974	755	538	688	705	ATF2	activating transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:784]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence	"ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction"	K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450;K04450	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016602//CCAAT-binding factor complex;GO:0035861//site of double-strand break;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex;GO:1902562//H4 histone acetyltransferase complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding;GO:0010485//H4 histone acetyltransferase activity;GO:0019901//protein kinase binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043522//leucine zipper domain binding;GO:0043565//sequence-specific DNA binding;GO:0044013//H2B histone acetyltransferase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001701//in utero embryonic development;GO:0001865//NK T cell differentiation;GO:0001889//liver development;GO:0001934//positive regulation of protein phosphorylation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003151//outflow tract morphogenesis;GO:0003360//brainstem development;GO:0003418//growth plate cartilage chondrocyte differentiation;GO:0003419//growth plate cartilage chondrocyte proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0006915//apoptotic process;GO:0006970//response to osmotic stress;GO:0006974//cellular response to DNA damage stimulus;GO:0007033//vacuole organization;GO:0007254//JNK cascade;GO:0007507//heart development;GO:0009414//response to water deprivation;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0016525//negative regulation of angiogenesis;GO:0018107//peptidyl-threonine phosphorylation;GO:0021742//abducens nucleus development;GO:0021743//hypoglossal nucleus development;GO:0021754//facial nucleus development;GO:0030509//BMP signaling pathway;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0034599//cellular response to oxidative stress;GO:0038066//p38MAPK cascade;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043525//positive regulation of neuron apoptotic process;GO:0043967//histone H4 acetylation;GO:0043969//histone H2B acetylation;GO:0044255//cellular lipid metabolic process;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050872//white fat cell differentiation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060052//neurofilament cytoskeleton organization;GO:0060245//detection of cell density;GO:0060612//adipose tissue development;GO:0072740//cellular response to anisomycin;GO:0097049//motor neuron apoptotic process;GO:0097186//amelogenesis;GO:0097284//hepatocyte apoptotic process;GO:0098586//cellular response to virus;GO:0110024//positive regulation of cardiac muscle myoblast proliferation;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902742//apoptotic process involved in development;GO:1990144//intrinsic apoptotic signaling pathway in response to hypoxia;GO:1990253//cellular response to leucine starvation"	TF_bZIP
ENSG00000115970	9.67	8.974	8.898	7.689	8.065	8.072	1214	1147	830	717	851	741	THADA	THADA armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:19217]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098554//cytoplasmic side of endoplasmic reticulum membrane	GO:0005515//protein binding	GO:0030488//tRNA methylation;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0055088//lipid homeostasis;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1990845//adaptive thermogenesis	--
ENSG00000115977	4.424	5.216	6.219	4.578	4.198	4.046	768	757	615	437	551	512	AAK1	AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035612//AP-2 adaptor complex binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0016310//phosphorylation;GO:0032880//regulation of protein localization;GO:0045747//positive regulation of Notch signaling pathway;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization;GO:0061024//membrane organization;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000115993	17.955	16.855	16.59	10.905	11.6	11.984	2189	2147	1485	1053	1224	1080	TRAK2	trafficking kinesin protein 2 [Source:HGNC Symbol;Acc:HGNC:13206]	Organismal Systems	Nervous system	ko04727//GABAergic synapse	K15374	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0032839//dendrite cytoplasm;GO:1904115//axon cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0050811//GABA receptor binding	GO:0006605//protein targeting;GO:0022008//neurogenesis;GO:0047496//vesicle transport along microtubule;GO:0048311//mitochondrion distribution;GO:0098957//anterograde axonal transport of mitochondrion;GO:0098972//anterograde dendritic transport of mitochondrion	--
ENSG00000115998	6.861	7.988	6.798	5.168	6.947	7.695	263	308	214	184	237	215	C2orf42	chromosome 2 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:26056]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000116001	18.321	12.176	15.235	10.847	15.329	19.287	1197	924	829	598	863	932	TIA1	TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0097165//nuclear stress granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001818//negative regulation of cytokine production;GO:0006915//apoptotic process;GO:0017148//negative regulation of translation;GO:0034063//stress granule assembly;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:1903608//protein localization to cytoplasmic stress granule"	--
ENSG00000116005	46.89	40.499	46.572	45.766	42.892	49.149	4838	4391	3500	3312	3820	3696	PCYOX1	prenylcysteine oxidase 1 [Source:HGNC Symbol;Acc:HGNC:20588]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K05906	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0034361//very-low-density lipoprotein particle;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	"GO:0001735//prenylcysteine oxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor"	GO:0030327//prenylated protein catabolic process;GO:0030328//prenylcysteine catabolic process;GO:1902476//chloride transmembrane transport	--
ENSG00000116014	0	0	0.04	0.128	0.035	0.041	0	0	1	1	1	1	KISS1R	KISS1 receptor [Source:HGNC Symbol;Acc:HGNC:4510]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04929//GnRH secretion	K08374;K08374	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000116016	98.994	101.373	86.298	81.515	84.839	88.999	10566	10895	6815	6441	7664	6924	EPAS1	endothelial PAS domain protein 1 [Source:HGNC Symbol;Acc:HGNC:3374]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05211//Renal cell carcinoma	K09095;K09095	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001892//embryonic placenta development;GO:0001974//blood vessel remodeling;GO:0002027//regulation of heart rate;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0010467//gene expression;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030324//lung development;GO:0042415//norepinephrine metabolic process;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043129//surfactant homeostasis;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048625//myoblast fate commitment;GO:0055072//iron ion homeostasis;GO:0071456//cellular response to hypoxia;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2000434//regulation of protein neddylation"	Others
ENSG00000116017	0.603	0.39	0.373	0.372	0.604	1.09	38	43	34	31	43	45	ARID3A	AT-rich interaction domain 3A [Source:HGNC Symbol;Acc:HGNC:3031]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045121//membrane raft	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	ARID
ENSG00000116030	52.942	49.203	57.937	54.724	49.023	60.007	1569	1484	1200	1210	1229	1313	SUMO1	small ubiquitin like modifier 1 [Source:HGNC Symbol;Acc:HGNC:12502]	Human Diseases;Genetic Information Processing	Cardiovascular disease;Translation	ko05418//Fluid shear stress and atherosclerosis;ko03013//Nucleocytoplasmic transport	K12160;K12160	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0097165//nuclear stress granule	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0015459//potassium channel regulator activity;GO:0019899//enzyme binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding;GO:0044388//small protein activating enzyme binding;GO:0044389//ubiquitin-like protein ligase binding;GO:1990381//ubiquitin-specific protease binding	"GO:0006281//DNA repair;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0016925//protein sumoylation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032880//regulation of protein localization;GO:0034605//cellular response to heat;GO:0042308//negative regulation of protein import into nucleus;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045759//negative regulation of action potential;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0060021//roof of mouth development;GO:0071276//cellular response to cadmium ion;GO:1902260//negative regulation of delayed rectifier potassium channel activity"	--
ENSG00000116031	0	0	0.07	0	0	0	0	0	2	0	0	0	CD207	CD207 molecule [Source:HGNC Symbol;Acc:HGNC:17935]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding	GO:0051607//defense response to virus	--
ENSG00000116032	0.118	0.292	0.06	0.119	0.052	0.04	8	20	3	6	3	2	GRIN3B	glutamate ionotropic receptor NMDA type subunit 3B [Source:HGNC Symbol;Acc:HGNC:16768]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Substance dependence;Neurodegenerative disease;Nervous system;Substance dependence;Substance dependence;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko05031//Amphetamine addiction;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05214;K05214;K05214;K05214;K05214;K05214;K05214;K05214;K05214	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0015276//ligand-gated ion channel activity;GO:0016594//glycine binding;GO:0030594//neurotransmitter receptor activity;GO:0038023//signaling receptor activity;GO:0042165//neurotransmitter binding	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0051205//protein insertion into membrane;GO:0051924//regulation of calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000116035	0.951	0.248	1.203	0.762	0.639	0.4	23.39	6	21.85	13.68	13	7	VAX2	ventral anterior homeobox 2 [Source:HGNC Symbol;Acc:HGNC:12661]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007398//ectoderm development;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0007601//visual perception;GO:0009950//dorsal/ventral axis specification;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030900//forebrain development;GO:0043010//camera-type eye development;GO:0048048//embryonic eye morphogenesis;GO:0060041//retina development in camera-type eye"	Homeobox
ENSG00000116039	2.088	3.27	1.306	4.755	4.309	1.842	82.61	130	38.15	139.32	144	53	ATP6V1B1	ATPase H+ transporting V1 subunit B1 [Source:HGNC Symbol;Acc:HGNC:853]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0070062//extracellular exosome;GO:0098850//extrinsic component of synaptic vesicle membrane"	"GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015078//proton transmembrane transporter activity;GO:0016787//hydrolase activity;GO:0044877//protein-containing complex binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0001503//ossification;GO:0003091//renal water homeostasis;GO:0003096//renal sodium ion transport;GO:0006693//prostaglandin metabolic process;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006885//regulation of pH;GO:0006996//organelle organization;GO:0007605//sensory perception of sound;GO:0010468//regulation of gene expression;GO:0016241//regulation of macroautophagy;GO:0030534//adult behavior;GO:0035812//renal sodium excretion;GO:0042048//olfactory behavior;GO:0042472//inner ear morphogenesis;GO:0045851//pH reduction;GO:0046034//ATP metabolic process;GO:0055064//chloride ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0097254//renal tubular secretion;GO:1902600//proton transmembrane transport	--
ENSG00000116044	42.895	40.108	35.233	33.048	31.618	41.203	2177	2060	1326	1239	1377	1513	NFE2L2	"nuclear factor, erythroid 2 like 2 [Source:HGNC Symbol;Acc:HGNC:7782]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases	"Cancer: overview;Neurodegenerative disease;Cancer: overview;Cardiovascular disease;Folding, sorting and degradation;Cancer: specific types;Cardiovascular disease"	ko05200//Pathways in cancer;ko05012//Parkinson disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis	K05638;K05638;K05638;K05638;K05638;K05638;K05638	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0010226//response to lithium ion;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:0010628//positive regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010976//positive regulation of neuron projection development;GO:0016567//protein ubiquitination;GO:0030194//positive regulation of blood coagulation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034599//cellular response to oxidative stress;GO:0034976//response to endoplasmic reticulum stress;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0036499//PERK-mediated unfolded protein response;GO:0042149//cellular response to glucose starvation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045088//regulation of innate immune response;GO:0045454//cell redox homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0046223//aflatoxin catabolic process;GO:0046326//positive regulation of glucose import;GO:0060548//negative regulation of cell death;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070301//cellular response to hydrogen peroxide;GO:0071280//cellular response to copper ion;GO:0071356//cellular response to tumor necrosis factor;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0071498//cellular response to fluid shear stress;GO:0071499//cellular response to laminar fluid shear stress;GO:0140467//integrated stress response signaling;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:1903788//positive regulation of glutathione biosynthetic process;GO:1904385//cellular response to angiotensin;GO:1904753//negative regulation of vascular associated smooth muscle cell migration;GO:2000121//regulation of removal of superoxide radicals;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process"	TF_bZIP
ENSG00000116062	18.422	18.379	16.61	13.239	14.154	16.205	1560.07	1499.46	1072.22	880.48	1061.97	912.65	MSH6	mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Replication and repair	ko05200//Pathways in cancer;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko03430//Mismatch repair	K08737;K08737;K08737;K08737	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0032301//MutSalpha complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0019899//enzyme binding;GO:0030983//mismatched DNA binding;GO:0032137//guanine/thymine mispair binding;GO:0032142//single guanine insertion binding;GO:0032143//single thymine insertion binding;GO:0032357//oxidized purine DNA binding;GO:0032405//MutLalpha complex binding;GO:0035064//methylated histone binding;GO:0043531//ADP binding"	GO:0000710//meiotic mismatch repair;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0008340//determination of adult lifespan;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009411//response to UV;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0045190//isotype switching;GO:0045910//negative regulation of DNA recombination;GO:0051096//positive regulation of helicase activity;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000116095	4.627	4.147	2.963	3.865	2.632	4.198	627	563	369	385	439	464	PLEKHA3	pleckstrin homology domain containing A3 [Source:HGNC Symbol;Acc:HGNC:14338]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0008150//biological_process;GO:0035627//ceramide transport;GO:0120009//intermembrane lipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000116096	16.564	17.149	17.824	20.453	18.729	20.359	492	512	391	450	470	440	SPR	sepiapterin reductase [Source:HGNC Symbol;Acc:HGNC:11257]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K00072;K00072	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004033//aldo-keto reductase (NADP) activity;GO:0004757//sepiapterin reductase activity;GO:0016491//oxidoreductase activity;GO:0050661//NADP binding	GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0006809//nitric oxide biosynthetic process	--
ENSG00000116106	8.934	9.515	10.537	8.4	8.233	9.621	1019	960	823	803	892	803	EPHA4	EPH receptor A4 [Source:HGNC Symbol;Acc:HGNC:3388]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05105	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0043235//receptor complex;GO:0043679//axon terminus;GO:0044295//axonal growth cone;GO:0044297//cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0000166//nucleotide binding;GO:0001540//amyloid-beta binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042731//PH domain binding;GO:0042802//identical protein binding;GO:0046875//ephrin receptor binding;GO:0097161//DH domain binding;GO:1990782//protein tyrosine kinase binding	GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007628//adult walking behavior;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0008347//glial cell migration;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010977//negative regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021957//corticospinal tract morphogenesis;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0033674//positive regulation of kinase activity;GO:0034332//adherens junction organization;GO:0043087//regulation of GTPase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0045785//positive regulation of cell adhesion;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0048681//negative regulation of axon regeneration;GO:0048710//regulation of astrocyte differentiation;GO:0050770//regulation of axonogenesis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050821//protein stabilization;GO:0061001//regulation of dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0072178//nephric duct morphogenesis;GO:0090102//cochlea development;GO:0097155//fasciculation of sensory neuron axon;GO:0097156//fasciculation of motor neuron axon;GO:0097485//neuron projection guidance;GO:0098883//synapse pruning;GO:0106030//neuron projection fasciculation;GO:1900038//negative regulation of cellular response to hypoxia;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1902004//positive regulation of amyloid-beta formation;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1903051//negative regulation of proteolysis involved in cellular protein catabolic process;GO:1904646//cellular response to amyloid-beta;GO:1905244//regulation of modification of synaptic structure;GO:2001108//positive regulation of Rho guanyl-nucleotide exchange factor activity	--
ENSG00000116117	10	9.59	9.57	7.361	7.782	7.812	1601	1503	1148	876	1075	932	PARD3B	par-3 family cell polarity regulator beta [Source:HGNC Symbol;Acc:HGNC:14446]	-	-	-	-	GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043296//apical junction complex	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding	GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0008104//protein localization;GO:0030010//establishment of cell polarity;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0051301//cell division;GO:0051660//establishment of centrosome localization	--
ENSG00000116120	3.715	3.795	3.418	3.908	3.596	3.362	521	535	354	406	426	343	FARSB	phenylalanyl-tRNA synthetase subunit beta [Source:HGNC Symbol;Acc:HGNC:17800]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01890	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009328//phenylalanine-tRNA ligase complex;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004826//phenylalanine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0051290//protein heterotetramerization	--
ENSG00000116127	3.13	1.891	1.603	1.286	1.439	1.231	532	355	216	161	249	155	ALMS1	ALMS1 centrosome and basal body associated protein [Source:HGNC Symbol;Acc:HGNC:428]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	GO:0003674//molecular_function;GO:0008017//microtubule binding	GO:0016197//endosomal transport;GO:0046599//regulation of centriole replication;GO:0051492//regulation of stress fiber assembly;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000116128	6.376	6.992	6.939	6.358	7.752	7.094	797	866.97	644	591	812	642	BCL9	BCL9 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:1008]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:1990907//beta-catenin-TCF complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding	GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0016055//Wnt signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060070//canonical Wnt signaling pathway	--
ENSG00000116132	18.433	17.331	15.62	7.479	7.949	9.355	1385	1293	849	412	495	519	PRRX1	paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0071837//HMG box domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030326//embryonic limb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048664//neuron fate determination;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048844//artery morphogenesis;GO:0051216//cartilage development;GO:0060021//roof of mouth development;GO:0070570//regulation of neuron projection regeneration;GO:0097150//neuronal stem cell population maintenance;GO:0100026//positive regulation of DNA repair by transcription from RNA polymerase II promoter"	Homeobox
ENSG00000116133	92.757	98.757	108.465	148.003	138.219	146.812	8133	8689	6981	9585	10185	9351	DHCR24	24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K09828;K09828	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000246//delta24(24-1) sterol reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0019899//enzyme binding;GO:0042605//peptide antigen binding;GO:0050614//delta24-sterol reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0007265//Ras protein signal transduction;GO:0008104//protein localization;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0009725//response to hormone;GO:0009888//tissue development;GO:0016125//sterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0030539//male genitalia development;GO:0031639//plasminogen activation;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0042987//amyloid precursor protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043588//skin development;GO:0051726//regulation of cell cycle;GO:0061024//membrane organization;GO:1901214//regulation of neuron death	--
ENSG00000116138	7.182	6.238	6.726	6.149	6.195	6.841	801	726	551	486	612	562	DNAJC16	DnaJ heat shock protein family (Hsp40) member C16 [Source:HGNC Symbol;Acc:HGNC:29157]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000116141	1.679	1.582	1.492	1.484	1.716	1.572	180	176	115	120	160	125	MARK1	microtubule affinity regulating kinase 1 [Source:HGNC Symbol;Acc:HGNC:6896]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030425//dendrite;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001786//phosphatidylserine binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0070300//phosphatidic acid binding;GO:0106310//protein serine kinase activity"	GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010975//regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0050773//regulation of dendrite development;GO:0051654//establishment of mitochondrion localization	--
ENSG00000116147	0.019	0	0	0	0	0.013	2	0	0	0	0	1	TNR	tenascin R [Source:HGNC Symbol;Acc:HGNC:11953]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04512//ECM-receptor interaction	K06252;K06252;K06252;K06252;K06252	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0072534//perineuronal net;GO:0090733//tenascin complex;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007411//axon guidance;GO:0008306//associative learning;GO:0010977//negative regulation of neuron projection development;GO:0022029//telencephalon cell migration;GO:0022408//negative regulation of cell-cell adhesion;GO:0030155//regulation of cell adhesion;GO:0030198//extracellular matrix organization;GO:0030334//regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0035641//locomotory exploration behavior;GO:0045595//regulation of cell differentiation;GO:0048692//negative regulation of axon extension involved in regeneration;GO:0050767//regulation of neurogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050805//negative regulation of synaptic transmission;GO:0050808//synapse organization;GO:0050885//neuromuscular process controlling balance;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0051971//positive regulation of transmission of nerve impulse;GO:0060291//long-term synaptic potentiation"	--
ENSG00000116151	3.95	3.197	3.763	3.975	2.6	4.26	137	128	108	122	89	119	MORN1	MORN repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25852]	-	-	-	-	-	-	-	--
ENSG00000116157	25.263	30.285	27.672	27.221	23.541	23.075	644	776	521	514	507	428	GPX7	glutathione peroxidase 7 [Source:HGNC Symbol;Acc:HGNC:4559]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0004096//catalase activity;GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006979//response to oxidative stress;GO:0034599//cellular response to oxidative stress;GO:0098869//cellular oxidant detoxification	--
ENSG00000116161	57.874	45.988	71.203	52.53	28.994	18.933	1069	1092	822	796	788	676	CACYBP	calcyclin binding protein [Source:HGNC Symbol;Acc:HGNC:30423]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04507	GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0030877//beta-catenin destruction complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding	GO:0007507//heart development;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000116171	80.226	70.632	67.468	63.488	70.374	67.474	2250.05	2090.01	1542	1351	1689	1438	SCP2	sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606]	Metabolism;Cellular Processes;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Endocrine system;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids;ko00120//Primary bile acid biosynthesis	K08764;K08764;K08764;K08764;K08764;K08764	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000062//fatty-acyl-CoA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transfer activity;GO:0015485//cholesterol binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0032934//sterol binding;GO:0033814//propanoyl-CoA C-acyltransferase activity;GO:0036042//long-chain fatty acyl-CoA binding;GO:0050632//propionyl-CoA C2-trimethyltridecanoyltransferase activity;GO:0050633//acetyl-CoA C-myristoyltransferase activity;GO:0070538//oleic acid binding;GO:0120019//phosphatidylcholine transfer activity;GO:0120020//cholesterol transfer activity"	GO:0006629//lipid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006694//steroid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0006701//progesterone biosynthetic process;GO:0006869//lipid transport;GO:0007031//peroxisome organization;GO:0008206//bile acid metabolic process;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0032367//intracellular cholesterol transport;GO:0032385//positive regulation of intracellular cholesterol transport;GO:0032959//inositol trisphosphate biosynthetic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0036109//alpha-linolenic acid metabolic process;GO:0045940//positive regulation of steroid metabolic process;GO:0071071//regulation of phospholipid biosynthetic process;GO:0072659//protein localization to plasma membrane;GO:0120009//intermembrane lipid transfer;GO:1901373//lipid hydroperoxide transport	--
ENSG00000116176	0	0	0	0	0	0	0	0	0	0	0	0	TPSG1	tryptase gamma 1 [Source:HGNC Symbol;Acc:HGNC:14134]	-	-	-	-	GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000116183	0.209	0.149	0.115	0.081	0.088	0.137	42	30	17	12	15	20	PAPPA2	pappalysin 2 [Source:HGNC Symbol;Acc:HGNC:14615]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001558//regulation of cell growth;GO:0006508//proteolysis;GO:0009651//response to salt stress;GO:0044267//cellular protein metabolic process;GO:0060349//bone morphogenesis	--
ENSG00000116191	2.58	2.302	1.38	1.263	1.581	2.602	322	262	158	145	158	184	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:HGNC:30279]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0032485//regulation of Ral protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000116194	0.084	0.063	0.057	0.028	0.107	0	4	3	2	1	1	0	ANGPTL1	angiopoietin like 1 [Source:HGNC Symbol;Acc:HGNC:489]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway	--
ENSG00000116198	9.771	9.767	10.028	9.272	8.517	9.604	877	881	644	604	669	631	CEP104	centrosomal protein 104 [Source:HGNC Symbol;Acc:HGNC:24866]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0016594//glycine binding;GO:0016595//glutamate binding;GO:0016596//thienylcyclohexylpiperidine binding	-	--
ENSG00000116199	6.961	7.935	7.701	6.051	6.439	5.961	865	882	595	557	676	539	FAM20B	FAM20B glycosaminoglycan xylosylkinase [Source:HGNC Symbol;Acc:HGNC:23017]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0046872//metal ion binding"	GO:0016310//phosphorylation;GO:0030166//proteoglycan biosynthetic process	--
ENSG00000116205	2.999	2.56	2.486	1.286	1.695	2.295	524	492	281	206	282	225	TCEANC2	transcription elongation factor A N-terminal and central domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26494]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated"	--
ENSG00000116209	349.962	351.593	296.519	207.765	201.663	195.91	9847	10082	6137	4189	4848	4179	TMEM59	transmembrane protein 59 [Source:HGNC Symbol;Acc:HGNC:1239]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0005515//protein binding	GO:0006508//proteolysis;GO:0006914//autophagy;GO:0010508//positive regulation of autophagy;GO:0010955//negative regulation of protein processing;GO:0090285//negative regulation of protein glycosylation in Golgi;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000116212	22.913	27.241	22.665	17.495	17.766	16.797	807	928	575	435	521	426	LRRC42	leucine rich repeat containing 42 [Source:HGNC Symbol;Acc:HGNC:28792]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000116213	5.939	7.312	4.739	4.364	5.421	8.189	162	207	120	107	115	165	WRAP73	"WD repeat containing, antisense to TP73 [Source:HGNC Symbol;Acc:HGNC:12759]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0072686//mitotic spindle;GO:1990811//MWP complex	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0030030//cell projection organization;GO:0090307//mitotic spindle assembly;GO:1902440//protein localization to mitotic spindle pole body;GO:1902857//positive regulation of non-motile cilium assembly	--
ENSG00000116218	0	0	0	0	0	0	0	0	0	0	0	0	NPHS2	"NPHS2 stomatin family member, podocin [Source:HGNC Symbol;Acc:HGNC:13394]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0032991//protein-containing complex;GO:0036057//slit diaphragm;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0003094//glomerular filtration;GO:0031532//actin cytoskeleton reorganization;GO:0072249//metanephric glomerular visceral epithelial cell development	--
ENSG00000116221	43.24	45.536	45.18	47.477	42.751	42.872	1335	1405	1025	1084	1112	964	MRPL37	mitochondrial ribosomal protein L37 [Source:HGNC Symbol;Acc:HGNC:14034]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000116237	42.232	41.748	42.133	40.788	41.097	44.676	3061	2917	2259	2178	2467	2374	ICMT	isoprenylcysteine carboxyl methyltransferase [Source:HGNC Symbol;Acc:HGNC:5350]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K00587	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003880//protein C-terminal carboxyl O-methyltransferase activity;GO:0004671//protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0006464//cellular protein modification process;GO:0006481//C-terminal protein methylation;GO:0006612//protein targeting to membrane;GO:0032259//methylation;GO:0046498//S-adenosylhomocysteine metabolic process;GO:0046499//S-adenosylmethioninamine metabolic process	--
ENSG00000116251	176.679	187.245	184.443	201.966	158.148	172.043	6633	6797.9	5168	5536	5346	4795	RPL22	ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:10315]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02891;K02891	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0045182//translation regulator activity	"GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0046632//alpha-beta T cell differentiation;GO:0099577//regulation of translation at presynapse, modulating synaptic transmission"	--
ENSG00000116254	0.269	0.502	0.382	0.459	0.811	0.821	34	58	39	60	117	67	CHD5	chromodomain helicase DNA binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16816]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016581//NuRD complex;GO:0016607//nuclear speck;GO:0043233//organelle lumen	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0061628//H3K27me3 modified histone binding;GO:0140658//ATP-dependent chromatin remodeler activity	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0021895//cerebral cortex neuron differentiation;GO:0030154//cell differentiation;GO:0032508//DNA duplex unwinding;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0043967//histone H4 acetylation;GO:0098532//histone H3-K27 trimethylation;GO:1901798//positive regulation of signal transduction by p53 class mediator"	--
ENSG00000116260	68.207	72.552	76.581	85.468	80.184	83.935	4109	4500	3390	3756	4126	3934	QSOX1	quiescin sulfhydryl oxidase 1 [Source:HGNC Symbol;Acc:HGNC:9756]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031093//platelet alpha granule lumen;GO:0035580//specific granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0003756//protein disulfide isomerase activity;GO:0016491//oxidoreductase activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0016972//thiol oxidase activity;GO:0071949//FAD binding	GO:0006457//protein folding;GO:0016242//negative regulation of macroautophagy;GO:0085029//extracellular matrix assembly	--
ENSG00000116266	10.537	8.402	9.704	9.728	7.658	10.116	544	436	370	372	334	380	STXBP3	syntaxin binding protein 3 [Source:HGNC Symbol;Acc:HGNC:11446]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0031091//platelet alpha granule;GO:0042581//specific granule;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0070820//tertiary granule;GO:0098793//presynapse	GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0044877//protein-containing complex binding	GO:0001678//cellular glucose homeostasis;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007269//neurotransmitter secretion;GO:0007420//brain development;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0022615//protein to membrane docking;GO:0030073//insulin secretion;GO:0032868//response to insulin;GO:0043312//neutrophil degranulation;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0046325//negative regulation of glucose import;GO:0070527//platelet aggregation;GO:0071346//cellular response to interferon-gamma	--
ENSG00000116273	8.084	8.069	8.591	8.1	7.416	8.812	609	611	478	452	472	483	PHF13	PHD finger protein 13 [Source:HGNC Symbol;Acc:HGNC:22983]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007076//mitotic chromosome condensation;GO:0030261//chromosome condensation;GO:0051301//cell division	--
ENSG00000116285	10.911	8.794	10.233	8.458	10.471	12.061	604	528	473	390	548	507	ERRFI1	ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding	GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0031953//negative regulation of protein autophosphorylation;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032869//cellular response to insulin stimulus;GO:0032966//negative regulation of collagen biosynthetic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043589//skin morphogenesis;GO:0045616//regulation of keratinocyte differentiation;GO:0048286//lung alveolus development;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0060426//lung vasculature development;GO:0060428//lung epithelium development;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071474//cellular hyperosmotic response;GO:0071549//cellular response to dexamethasone stimulus;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress	--
ENSG00000116288	135.524	145.836	146.972	137.437	130.853	132.258	2354	2472	1883	1779	1874	1690	PARK7	Parkinsonism associated deglycase [Source:HGNC Symbol;Acc:HGNC:16369]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K05687;K05687	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016605//PML body;GO:0030424//axon;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098793//presynapse	"GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005102//signaling receptor binding;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016532//superoxide dismutase copper chaperone activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0016787//hydrolase activity;GO:0019826//oxygen sensor activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019955//cytokine binding;GO:0036470//tyrosine 3-monooxygenase activator activity;GO:0036478//L-dopa decarboxylase activator activity;GO:0036524//protein deglycase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044388//small protein activating enzyme binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0045340//mercury ion binding;GO:0050681//androgen receptor binding;GO:0051920//peroxiredoxin activity;GO:0097110//scaffold protein binding;GO:0140297//DNA-binding transcription factor binding;GO:1903135//cupric ion binding;GO:1903136//cuprous ion binding;GO:1990381//ubiquitin-specific protease binding;GO:1990422//glyoxalase (glycolic acid-forming) activity"	"GO:0001933//negative regulation of protein phosphorylation;GO:0001963//synaptic transmission, dopaminergic;GO:0002866//positive regulation of acute inflammatory response to antigenic stimulus;GO:0006281//DNA repair;GO:0006469//negative regulation of protein kinase activity;GO:0006508//proteolysis;GO:0006517//protein deglycosylation;GO:0006914//autophagy;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007005//mitochondrion organization;GO:0007265//Ras protein signal transduction;GO:0007338//single fertilization;GO:0008344//adult locomotory behavior;GO:0009438//methylglyoxal metabolic process;GO:0010273//detoxification of copper ion;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016570//histone modification;GO:0019249//lactate biosynthetic process;GO:0030073//insulin secretion;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031397//negative regulation of protein ubiquitination;GO:0032091//negative regulation of protein binding;GO:0032148//activation of protein kinase B activity;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032757//positive regulation of interleukin-8 production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033182//regulation of histone ubiquitination;GO:0033234//negative regulation of protein sumoylation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0034599//cellular response to oxidative stress;GO:0034614//cellular response to reactive oxygen species;GO:0035065//regulation of histone acetylation;GO:0036471//cellular response to glyoxal;GO:0036526//peptidyl-cysteine deglycation;GO:0036527//peptidyl-arginine deglycation;GO:0036528//peptidyl-lysine deglycation;GO:0036529//protein deglycation, glyoxal removal;GO:0036530//protein deglycation, methylglyoxal removal;GO:0036531//glutathione deglycation;GO:0042177//negative regulation of protein catabolic process;GO:0042542//response to hydrogen peroxide;GO:0042593//glucose homeostasis;GO:0042743//hydrogen peroxide metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046295//glycolate biosynthetic process;GO:0046826//negative regulation of protein export from nucleus;GO:0050727//regulation of inflammatory response;GO:0050787//detoxification of mercury ion;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051881//regulation of mitochondrial membrane potential;GO:0051897//positive regulation of protein kinase B signaling;GO:0051899//membrane depolarization;GO:0060081//membrane hyperpolarization;GO:0060548//negative regulation of cell death;GO:0060765//regulation of androgen receptor signaling pathway;GO:0061727//methylglyoxal catabolic process to lactate;GO:0070301//cellular response to hydrogen peroxide;GO:0070994//detection of oxidative stress;GO:0098869//cellular oxidant detoxification;GO:0106044//guanine deglycation;GO:0106045//guanine deglycation, methylglyoxal removal;GO:0106046//guanine deglycation, glyoxal removal;GO:0110095//cellular detoxification of aldehyde;GO:0140041//cellular detoxification of methylglyoxal;GO:1900182//positive regulation of protein localization to nucleus;GO:1901215//negative regulation of neuron death;GO:1901671//positive regulation of superoxide dismutase activity;GO:1901984//negative regulation of protein acetylation;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902903//regulation of supramolecular fiber organization;GO:1902958//positive regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1903073//negative regulation of death-inducing signaling complex assembly;GO:1903094//negative regulation of protein K48-linked deubiquitination;GO:1903122//negative regulation of TRAIL-activated apoptotic signaling pathway;GO:1903168//positive regulation of pyrroline-5-carboxylate reductase activity;GO:1903178//positive regulation of tyrosine 3-monooxygenase activity;GO:1903181//positive regulation of dopamine biosynthetic process;GO:1903189//glyoxal metabolic process;GO:1903190//glyoxal catabolic process;GO:1903197//positive regulation of L-dopa biosynthetic process;GO:1903200//positive regulation of L-dopa decarboxylase activity;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:1903208//negative regulation of hydrogen peroxide-induced neuron death;GO:1903377//negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903384//negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1903599//positive regulation of autophagy of mitochondrion;GO:1905259//negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway;GO:2000157//negative regulation of ubiquitin-specific protease activity;GO:2000277//positive regulation of oxidative phosphorylation uncoupler activity;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2000825//positive regulation of androgen receptor activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"	--
ENSG00000116299	0.021	0.017	0.09	0.108	0.203	0.143	3	1	5	2	14	6	ELAPOR1	endosome-lysosome associated apoptosis and autophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:29618]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000045//autophagosome assembly;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0044090//positive regulation of vacuole organization;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000116329	0.01	0.026	0.021	0.014	0.031	0.071	2	5	3	2	5	10	OPRD1	opioid receptor delta 1 [Source:HGNC Symbol;Acc:HGNC:8153]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04022//cGMP-PKG signaling pathway;ko04071//Sphingolipid signaling pathway	K04213;K04213;K04213	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0031226//intrinsic component of plasma membrane;GO:0031982//vesicle;GO:0032590//dendrite membrane;GO:0043005//neuron projection;GO:0043679//axon terminus;GO:0045121//membrane raft;GO:0045211//postsynaptic membrane;GO:0097444//spine apparatus;GO:0098992//neuronal dense core vesicle;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0004930//G protein-coupled receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0033612//receptor serine/threonine kinase binding;GO:0038046//G protein-coupled enkephalin receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008344//adult locomotory behavior;GO:0010629//negative regulation of gene expression;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0042755//eating behavior;GO:0051881//regulation of mitochondrial membrane potential;GO:0051924//regulation of calcium ion transport;GO:0051930//regulation of sensory perception of pain;GO:0071363//cellular response to growth factor stimulus;GO:0071456//cellular response to hypoxia;GO:0097237//cellular response to toxic substance"	--
ENSG00000116337	25.625	25.926	27.409	25.138	27.808	27.637	1881	1891	1473	1381	1746	1468	AMPD2	adenosine monophosphate deaminase 2 [Source:HGNC Symbol;Acc:HGNC:469]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01490;K01490	GO:0005829//cytosol	GO:0003876//AMP deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019239//deaminase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006188//IMP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0032264//IMP salvage;GO:0046033//AMP metabolic process;GO:0052652//cyclic purine nucleotide metabolic process;GO:0072521//purine-containing compound metabolic process;GO:0097009//energy homeostasis	--
ENSG00000116350	23.869	21.864	23.545	19.957	18.688	22.241	1101	1007	804	693	738	749	SRSF4	serine and arginine rich splicing factor 4 [Source:HGNC Symbol;Acc:HGNC:10786]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K12893;K12893	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:1990825//sequence-specific mRNA binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032868//response to insulin;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000116353	4.612	4.826	4.36	4.722	4.175	3.807	227	245	165	181	179	139	MECR	mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko00061//Fatty acid biosynthesis	K07512;K07512;K07512;K07512	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0016491//oxidoreductase activity;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process	--
ENSG00000116396	1.825	1.54	0.868	3.56	3.17	2.567	175	137	56	260	309	189	KCNC4	potassium voltage-gated channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:6236]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000116406	7.033	5.007	5.47	4.18	5.228	5.708	972	701	564	409	621	568	EDEM3	ER degradation enhancing alpha-mannosidase like protein 3 [Source:HGNC Symbol;Acc:HGNC:16787]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10086	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0044322//endoplasmic reticulum quality control compartment	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006986//response to unfolded protein;GO:1904380//endoplasmic reticulum mannose trimming;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway	--
ENSG00000116455	11.471	11.581	12.669	10.918	10.34	12.325	566	593	450	412	445	447	WDR77	WD repeat domain 77 [Source:HGNC Symbol;Acc:HGNC:29652]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0034709//methylosome	GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000387//spliceosomal snRNP assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007309//oocyte axis specification;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0043985//histone H4-R3 methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development"	--
ENSG00000116459	89.241	90.066	93.488	99.208	83.476	95.977	2664	2668	1983	2131	2094	2029	ATP5PB	ATP synthase peripheral stalk-membrane subunit b [Source:HGNC Symbol;Acc:HGNC:840]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02127;K02127;K02127;K02127;K02127;K02127;K02127;K02127;K02127;K02127;K02127	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0021762//substantia nigra development;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000116473	20.979	19.798	20.317	18.585	17.898	21.258	766	752	561	529	580	588	RAP1A	"RAP1A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9855]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cardiovascular disease;Cellular community - eukaryotes;Immune system;Cellular community - eukaryotes;Endocrine and metabolic disease;Immune system;Nervous system;Immune system;Digestive system;Cancer: specific types;Nervous system	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04530//Tight junction;ko04934//Cushing syndrome;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04972//Pancreatic secretion;ko05211//Renal cell carcinoma;ko04720//Long-term potentiation	K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353;K04353	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0035579//specific granule membrane;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0031267//small GTPase binding;GO:0044877//protein-containing complex binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development;GO:0032486//Rap protein signal transduction;GO:0038180//nerve growth factor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0045860//positive regulation of protein kinase activity;GO:0061028//establishment of endothelial barrier;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:0072659//protein localization to plasma membrane;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1901888//regulation of cell junction assembly;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000116478	14.363	12.614	15.212	15.211	15.411	17.237	631	557	489	495	572	543	HDAC1	histone deacetylase 1 [Source:HGNC Symbol;Acc:HGNC:4852]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Immune system;Cancer: overview;Substance dependence;Cancer: overview;Cell growth and death;Endocrine system;Cancer: specific types;Substance dependence;Aging;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism;ko05206//MicroRNAs in cancer;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko05220//Chronic myeloid leukemia;ko05031//Amphetamine addiction;ko04213//Longevity regulating pathway - multiple species;ko04330//Notch signaling pathway	K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0016581//NuRD complex;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0019899//enzyme binding;GO:0031492//nucleosomal DNA binding;GO:0033558//protein deacetylase activity;GO:0035851//Krueppel-associated box domain binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051059//NF-kappaB binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006476//protein deacetylation;GO:0007492//endoderm development;GO:0007623//circadian rhythm;GO:0008284//positive regulation of cell population proliferation;GO:0009913//epidermal cell differentiation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016575//histone deacetylation;GO:0021766//hippocampus development;GO:0030182//neuron differentiation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042659//regulation of cell fate specification;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043922//negative regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0052548//regulation of endopeptidase activity;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060789//hair follicle placode formation;GO:0061029//eyelid development in camera-type eye;GO:0061198//fungiform papilla formation;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900221//regulation of amyloid-beta clearance;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:2000273//positive regulation of signaling receptor activity;GO:2000736//regulation of stem cell differentiation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000116489	38.622	35.048	35.85	31.08	31.291	35.322	1889	1723	1295	1126	1293	1257	CAPZA1	capping actin protein of muscle Z-line subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:1488]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K10364	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008290//F-actin capping protein complex;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome;GO:0071203//WASH complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0034329//cell junction assembly;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping;GO:0065003//protein-containing complex assembly	--
ENSG00000116497	6.966	5.388	5.713	5.808	6.44	6.061	523	474	334	345	442	386	S100PBP	S100P binding protein [Source:HGNC Symbol;Acc:HGNC:25768]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000116514	2.828	3.173	2.746	2.709	2.425	2.624	154	175	111	110	113	105	RNF19B	ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044194//cytolytic granule	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042267//natural killer cell mediated cytotoxicity;GO:0051865//protein autoubiquitination	--
ENSG00000116521	38.151	42.682	44.805	51.637	48.157	48.242	1221	1373	1059	1224	1302	1123	SCAMP3	secretory carrier membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:10565]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0031625//ubiquitin protein ligase binding	GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport	--
ENSG00000116525	1.288	1.522	1.53	1.825	2.431	1.805	102	120	86	107	128	104	TRIM62	tripartite motif containing 62 [Source:HGNC Symbol;Acc:HGNC:25574]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0002376//immune system process;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0016567//protein ubiquitination;GO:0019076//viral release from host cell;GO:0032897//negative regulation of viral transcription;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044314//protein K27-linked ubiquitination;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1905036//positive regulation of antifungal innate immune response"	--
ENSG00000116539	9.901	7.047	6.062	4.271	5.416	5.795	2375	1691	1069	755	1100	990	ASH1L	ASH1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:19088]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K06101;K06101	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0005923//bicellular tight junction;GO:0016586//RSC-type complex;GO:0030054//cell junction;GO:0031981//nuclear lumen	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0046975//histone methyltransferase activity (H3-K36 specific)	GO:0001501//skeletal system development;GO:0002674//negative regulation of acute inflammatory response;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006807//nitrogen compound metabolic process;GO:0007338//single fertilization;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0030317//flagellated sperm motility;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043409//negative regulation of MAPK cascade;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046697//decidualization;GO:0048733//sebaceous gland development;GO:0050728//negative regulation of inflammatory response;GO:0051567//histone H3-K9 methylation;GO:0051568//histone H3-K4 methylation;GO:0061038//uterus morphogenesis;GO:0097676//histone H3-K36 dimethylation;GO:1903699//tarsal gland development;GO:1903709//uterine gland development	--
ENSG00000116544	0.417	0.379	0.164	0.282	0.255	0.304	31	31	9	17	16	18	DLGAP3	DLG associated protein 3 [Source:HGNC Symbol;Acc:HGNC:30368]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0098981//cholinergic synapse;GO:0099572//postsynaptic specialization	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0023052//signaling;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0099563//modification of synaptic structure	--
ENSG00000116560	55.231	53.504	60.711	53.712	50.534	58.01	3097	2802	2363	1940	2302	2250	SFPQ	splicing factor proline and glutamine rich [Source:HGNC Symbol;Acc:HGNC:10774]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0032839//dendrite cytoplasm;GO:0042382//paraspeckles;GO:0090575//RNA polymerase II transcription regulator complex	GO:0000976//transcription cis-regulatory region binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000724//double-strand break repair via homologous recombination;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0042752//regulation of circadian rhythm;GO:0042754//negative regulation of circadian rhythm;GO:0045087//innate immune response;GO:0045876//positive regulation of sister chromatid cohesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051276//chromosome organization;GO:0051726//regulation of cell cycle;GO:0070932//histone H3 deacetylation;GO:0098963//dendritic transport of messenger ribonucleoprotein complex;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway"	Others
ENSG00000116574	4.523	3.883	3.935	4.465	4.85	6.417	372	321	239	272	337	384	RHOU	ras homolog family member U [Source:HGNC Symbol;Acc:HGNC:17794]	-	-	-	-	GO:0000139//Golgi membrane;GO:0002102//podosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0032488//Cdc42 protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000116580	5.6	5.473	5.759	4.213	5.014	4.745	836.7	849.65	623.3	460.47	629.02	528.21	GON4L	gon-4 like [Source:HGNC Symbol;Acc:HGNC:25973]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0030183//B cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	Others
ENSG00000116584	17.651	13.86	13.413	12.087	14.79	13.458	916	830	621	557	683	672	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:682]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Cellular community - eukaryotes;Cardiovascular disease	ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko04530//Tight junction;ko05418//Fluid shear stress and atherosclerosis	K12791;K12791;K12791;K12791	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0002376//immune system process;GO:0006886//intracellular protein transport;GO:0007015//actin filament organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035023//regulation of Rho protein signal transduction;GO:0042127//regulation of cell population proliferation;GO:0045087//innate immune response;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051301//cell division;GO:0055059//asymmetric neuroblast division;GO:0060546//negative regulation of necroptotic process;GO:0071225//cellular response to muramyl dipeptide;GO:0071356//cellular response to tumor necrosis factor;GO:0071474//cellular hyperosmotic response;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:2001224//positive regulation of neuron migration	--
ENSG00000116586	24.413	26.453	32.629	29.346	23.616	26.568	314	341	310	280	257	249	LAMTOR2	"late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 [Source:HGNC Symbol;Acc:HGNC:29796]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20398	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0071986//Ragulator complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0001558//regulation of cell growth;GO:0010761//fibroblast migration;GO:0032008//positive regulation of TOR signaling;GO:0034613//cellular protein localization;GO:0038202//TORC1 signaling;GO:0043410//positive regulation of MAPK cascade;GO:0050790//regulation of catalytic activity;GO:0071230//cellular response to amino acid stimulus;GO:0150116//regulation of cell-substrate junction organization;GO:1902414//protein localization to cell junction	--
ENSG00000116604	10.309	10.905	9.279	10.214	10.33	11.73	946	942	628	695	867	769	MEF2D	myocyte enhancer factor 2D [Source:HGNC Symbol;Acc:HGNC:6997]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Endocrine system	"ko04022//cGMP-PKG signaling pathway;ko04371//Apelin signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action"	K09262;K09262;K09262	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0002062//chondrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007512//adult heart development;GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation"	SRF
ENSG00000116641	26.349	20.887	21.602	18.79	19.225	21.513	3056	2571	1965	1684	2089	1946	DOCK7	dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190]	-	-	-	-	GO:0005925//focal adhesion;GO:0008180//COP9 signalosome;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045178//basal part of cell	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000226//microtubule cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0022027//interkinetic nuclear migration;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043547//positive regulation of GTPase activity;GO:0045200//establishment of neuroblast polarity;GO:0050767//regulation of neurogenesis;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1904754//positive regulation of vascular associated smooth muscle cell migration	--
ENSG00000116649	33.386	37.165	34.947	41.276	43.073	33.513	871	973	673	793	943	629	SRM	spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism	K00797;K00797;K00797;K00797	GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004766//spermidine synthase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0008295//spermidine biosynthetic process;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000116661	87.091	76.723	90.337	63.265	69.42	112.763	2332	2061	1784	1254	1568	2192	FBXO2	F-box protein 2 [Source:HGNC Symbol;Acc:HGNC:13581]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K10099;K10099	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0019005//SCF ubiquitin ligase complex;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle	GO:0001540//amyloid-beta binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0061630//ubiquitin protein ligase activity	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006516//glycoprotein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031396//regulation of protein ubiquitination;GO:0044267//cellular protein metabolic process	--
ENSG00000116663	4.941	5.78	5.845	6.446	6.046	6.608	148	174	127	143	153	144	FBXO6	F-box protein 6 [Source:HGNC Symbol;Acc:HGNC:13585]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10100	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0061630//ubiquitin protein ligase activity	GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006516//glycoprotein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000116667	4.114	3.408	4.13	4.96	3.674	4.468	437	384	326	382	380	360	C1orf21	chromosome 1 open reading frame 21 [Source:HGNC Symbol;Acc:HGNC:15494]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000116668	1.824	1.477	1.402	1.257	1.411	1.717	129	99	82	72	87	96	SWT1	SWT1 RNA endoribonuclease homolog [Source:HGNC Symbol;Acc:HGNC:16785]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000116670	14.249	16.48	14.543	16.93	16.051	14.736	316	369	236	273	300	239	MAD2L2	mitotic arrest deficient 2 like 2 [Source:HGNC Symbol;Acc:HGNC:6764]	Cellular Processes;Cellular Processes;Organismal Systems;Human Diseases	Cell growth and death;Cell growth and death;Endocrine system;Infectious disease: bacterial	ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko05100//Bacterial invasion of epithelial cells	K13728;K13728;K13728;K13728	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016035//zeta DNA polymerase complex;GO:0035861//site of double-strand break	GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0002208//somatic diversification of immunoglobulins involved in immune response;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0042177//negative regulation of protein catabolic process;GO:0042276//error-prone translesion synthesis;GO:0042772//DNA damage response, signal transduction resulting in transcription;GO:0043247//telomere maintenance in response to DNA damage;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045830//positive regulation of isotype switching;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000116675	2.689	2.506	2.432	2.301	2.817	2.589	212	191	161	160	205	175	DNAJC6	DnaJ heat shock protein family (Hsp40) member C6 [Source:HGNC Symbol;Acc:HGNC:15469]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K09526	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098793//presynapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0030276//clathrin binding	GO:0006470//protein dephosphorylation;GO:0016191//synaptic vesicle uncoating;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0072318//clathrin coat disassembly;GO:0072583//clathrin-dependent endocytosis;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000116678	1.687	1.622	1.075	1.127	1.552	1.191	164.01	157.05	83.24	88	112.78	82	LEPR	leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04152//AMPK signaling pathway;ko04920//Adipocytokine signaling pathway	K05062;K05062;K05062;K05062;K05062;K05062	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0019955//cytokine binding;GO:0038021//leptin receptor activity;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0005977//glycogen metabolic process;GO:0006112//energy reserve metabolic process;GO:0006909//phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0007275//multicellular organism development;GO:0008203//cholesterol metabolic process;GO:0010507//negative regulation of autophagy;GO:0014009//glial cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0019953//sexual reproduction;GO:0030217//T cell differentiation;GO:0033210//leptin-mediated signaling pathway;GO:0042593//glucose homeostasis;GO:0044321//response to leptin;GO:0045721//negative regulation of gluconeogenesis;GO:0046850//regulation of bone remodeling;GO:0051049//regulation of transport;GO:0051346//negative regulation of hydrolase activity;GO:0060259//regulation of feeding behavior;GO:0097009//energy homeostasis;GO:0098868//bone growth;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0150104//transport across blood-brain barrier	--
ENSG00000116679	34.057	34.265	35.1	31.904	34.719	35.19	2860	2923	2166	1915	2487	2123	IVNS1ABP	influenza virus NS1A binding protein [Source:HGNC Symbol;Acc:HGNC:16951]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0008380//RNA splicing;GO:0009615//response to virus;GO:0031397//negative regulation of protein ubiquitination;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000116685	24.264	25.109	29.783	28.93	29.541	27.349	1295	1371	1171	1131	1339	1087	KIAA2013	KIAA2013 [Source:HGNC Symbol;Acc:HGNC:28513]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000116688	37.998	39.572	41.782	41.208	43.062	44.391	2994	3281	2495	2439	2744	2529	MFN2	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	Human Diseases;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Immune system;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04621//NOD-like receptor signaling pathway;ko04137//Mitophagy - animal	K06030;K06030;K06030;K06030	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031306//intrinsic component of mitochondrial outer membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding	GO:0001825//blastocyst formation;GO:0006626//protein targeting to mitochondrion;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006986//response to unfolded protein;GO:0007005//mitochondrion organization;GO:0007006//mitochondrial membrane organization;GO:0008053//mitochondrial fusion;GO:0034497//protein localization to phagophore assembly site;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048593//camera-type eye morphogenesis;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051646//mitochondrion localization;GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process	--
ENSG00000116690	0	0	0	0.014	0	0	0	0	0	1	0	0	PRG4	proteoglycan 4 [Source:HGNC Symbol;Acc:HGNC:9364]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005044//scavenger receptor activity;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0030247//polysaccharide binding	GO:0006897//endocytosis;GO:0006955//immune response	--
ENSG00000116691	4.317	4.638	3.897	4.942	5.073	5.461	138	149	92	117	137	127	MIIP	migration and invasion inhibitory protein [Source:HGNC Symbol;Acc:HGNC:25715]	-	-	-	-	-	GO:0005515//protein binding	GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0030336//negative regulation of cell migration	--
ENSG00000116698	19.335	20.052	21.291	16.154	19.406	21.276	1783	1878	1403	1198	1599	1449	SMG7	SMG7 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:16792]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14409	GO:0005634//nucleus;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0051721//protein phosphatase 2A binding;GO:0070034//telomerase RNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006406//mRNA export from nucleus;GO:0019222//regulation of metabolic process;GO:0035303//regulation of dephosphorylation"	--
ENSG00000116701	0.183	0.778	0.112	0.03	0.207	0.092	4	12	1	1	8	3	NCF2	neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Immune system;Cancer: overview;Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Infectious disease: parasitic;Cardiovascular disease;Development and regeneration;Immune system	ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05140//Leishmaniasis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04670//Leukocyte transendothelial migration	K08010;K08010;K08010;K08010;K08010;K08010;K08010;K08010;K08010;K08010	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032010//phagolysosome;GO:0043020//NADPH oxidase complex	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0009055//electron transfer activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0031267//small GTPase binding	GO:0006801//superoxide metabolic process;GO:0006909//phagocytosis;GO:0006968//cellular defense response;GO:0022900//electron transport chain;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0045730//respiratory burst;GO:0050790//regulation of catalytic activity	--
ENSG00000116703	0	0	0	0	0	0	0	0	0	0	0	0	PDC	phosducin [Source:HGNC Symbol;Acc:HGNC:8759]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0004859//phospholipase inhibitor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0050896//response to stimulus	--
ENSG00000116704	3.916	3.749	3.552	4.204	4.045	4.601	503	484	337	400	439	430	SLC35D1	solute carrier family 35 member D1 [Source:HGNC Symbol;Acc:HGNC:20800]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005461//UDP-glucuronic acid transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463//UDP-N-acetylgalactosamine transmembrane transporter activity;GO:0015297//antiporter activity	GO:0008643//carbohydrate transport;GO:0015787//UDP-glucuronic acid transmembrane transport;GO:0015789//UDP-N-acetylgalactosamine transmembrane transport;GO:0055085//transmembrane transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000116711	1.122	0.583	0.998	0.678	0.872	0.944	67	35	44	30	44	41	PLA2G4A	phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0008374//O-acyltransferase activity;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016787//hydrolase activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0102545//phosphatidyl phospholipase B activity;GO:1902387//ceramide 1-phosphate binding	GO:0001516//prostaglandin biosynthetic process;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0006650//glycerophospholipid metabolic process;GO:0006663//platelet activating factor biosynthetic process;GO:0006690//icosanoid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0009395//phospholipid catabolic process;GO:0010572//positive regulation of platelet activation;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0032308//positive regulation of prostaglandin secretion;GO:0034478//phosphatidylglycerol catabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042127//regulation of cell population proliferation;GO:0043032//positive regulation of macrophage activation;GO:0046456//icosanoid biosynthetic process;GO:0046475//glycerophospholipid catabolic process;GO:0050482//arachidonic acid secretion;GO:0071236//cellular response to antibiotic	--
ENSG00000116717	20.611	16.641	26.708	23.453	21.61	28.915	578	467	545	486	512	590	GADD45A	growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death;Signal transduction;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04064//NF-kappa B signaling pathway;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05224//Breast cancer;ko05226//Gastric cancer;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding;GO:1990841//promoter-specific chromatin binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0016525//negative regulation of angiogenesis;GO:0033140//negative regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042770//signal transduction in response to DNA damage;GO:0043065//positive regulation of apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0046330//positive regulation of JNK cascade;GO:0051726//regulation of cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0071479//cellular response to ionizing radiation;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:1900745//positive regulation of p38MAPK cascade;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000116721	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF1	PRAME family member 1 [Source:HGNC Symbol;Acc:HGNC:28840]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000116726	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF12	PRAME family member 12 [Source:HGNC Symbol;Acc:HGNC:22125]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000116729	106.006	107.042	119.952	116.54	112.626	122.542	5452	5595	4465	4533	4966	4530	WLS	Wnt ligand secretion mediator [Source:HGNC Symbol;Acc:HGNC:30238]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0031301//integral component of organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0042802//identical protein binding	GO:0001707//mesoderm formation;GO:0006886//intracellular protein transport;GO:0009948//anterior/posterior axis specification;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0031017//exocrine pancreas development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0061355//Wnt protein secretion;GO:0061357//positive regulation of Wnt protein secretion;GO:0071529//cementum mineralization;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000116731	6.749	5.643	5.865	5.592	5.902	5.745	774	734	561	528	612	526	PRDM2	PR/SET domain 2 [Source:HGNC Symbol;Acc:HGNC:9347]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11432;K11432	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042054//histone methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008340//determination of adult lifespan;GO:0010468//regulation of gene expression;GO:0016571//histone methylation;GO:0032259//methylation;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000116741	0.823	1.103	0.969	0.917	1.185	1.032	23	31	20	19	28	21	RGS2	regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998]	Organismal Systems;Environmental Information Processing;Organismal Systems	Sensory system;Signal transduction;Endocrine system	ko04740//Olfactory transduction;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway	K18154;K18154;K18154	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0043005//neuron projection	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0010855//adenylate cyclase inhibitor activity;GO:0048487//beta-tubulin binding	GO:0001975//response to amphetamine;GO:0006417//regulation of translation;GO:0007049//cell cycle;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0010519//negative regulation of phospholipase activity;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010976//positive regulation of neuron projection development;GO:0017148//negative regulation of translation;GO:0030728//ovulation;GO:0031279//regulation of cyclase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0045471//response to ethanol;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0050873//brown fat cell differentiation;GO:0055119//relaxation of cardiac muscle;GO:0060087//relaxation of vascular associated smooth muscle;GO:0060135//maternal process involved in female pregnancy;GO:0060452//positive regulation of cardiac muscle contraction;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0140194//negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process;GO:1900924//negative regulation of glycine import across plasma membrane	--
ENSG00000116745	31.814	28.171	37.487	42.25	42.892	36.602	1719	1530	1496	1691	1958	1439	RPE65	retinoid isomerohydrolase RPE65 [Source:HGNC Symbol;Acc:HGNC:10294]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11158;K11158	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body	"GO:0001786//phosphatidylserine binding;GO:0004744//retinal isomerase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0031210//phosphatidylcholine binding;GO:0046872//metal ion binding;GO:0050251//retinol isomerase activity;GO:0052884//all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity;GO:0052885//all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity;GO:1901612//cardiolipin binding"	GO:0001523//retinoid metabolic process;GO:0001895//retina homeostasis;GO:0003407//neural retina development;GO:0006629//lipid metabolic process;GO:0006776//vitamin A metabolic process;GO:0007601//visual perception;GO:0007623//circadian rhythm;GO:0008286//insulin receptor signaling pathway;GO:0009416//response to light stimulus;GO:0010468//regulation of gene expression;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0043010//camera-type eye development;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0060041//retina development in camera-type eye;GO:0060042//retina morphogenesis in camera-type eye;GO:0071257//cellular response to electrical stimulus;GO:1901827//zeaxanthin biosynthetic process	--
ENSG00000116747	7.423	4.281	4.134	2.515	3.201	3.984	765.2	496.84	356.08	282.49	341.73	365.36	RO60	"Ro60, Y RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11313]"	Human Diseases	Immune disease	ko05322//Systemic lupus erythematosus	K11089	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0030620//U2 snRNA binding;GO:0046872//metal ion binding	GO:0002520//immune system development;GO:0006383//transcription by RNA polymerase III;GO:0007224//smoothened signaling pathway;GO:0009411//response to UV;GO:0010468//regulation of gene expression;GO:0030030//cell projection organization;GO:0035457//cellular response to interferon-alpha;GO:0060271//cilium assembly	--
ENSG00000116748	0	0	0	0	0	0	0	0	0	0	0	0	AMPD1	adenosine monophosphate deaminase 1 [Source:HGNC Symbol;Acc:HGNC:468]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01490;K01490	GO:0005829//cytosol	GO:0003876//AMP deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019239//deaminase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006188//IMP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0032263//GMP salvage;GO:0032264//IMP salvage;GO:0046033//AMP metabolic process	--
ENSG00000116750	8.013	7.434	7.739	5.152	6.274	10	346	310	240	150	182	261	UCHL5	ubiquitin C-terminal hydrolase L5 [Source:HGNC Symbol;Acc:HGNC:19678]	-	-	-	-	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031011//Ino80 complex;GO:0031597//cytosolic proteasome complex	GO:0003723//RNA binding;GO:0004843//thiol-dependent deubiquitinase;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070628//proteasome binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010951//negative regulation of endopeptidase activity;GO:0016579//protein deubiquitination;GO:0021670//lateral ventricle development;GO:0030901//midbrain development;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0048853//forebrain morphogenesis;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0061136//regulation of proteasomal protein catabolic process;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000116752	15.125	18.321	17.663	13.987	12.353	14.499	400	487	345	274	276	279	BCAS2	BCAS2 pre-mRNA processing factor [Source:HGNC Symbol;Acc:HGNC:975]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12861	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0005515//protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000116754	16.935	15.847	14.702	10.167	12.447	16.836	1039	944	651	438	612	740	SRSF11	serine and arginine rich splicing factor 11 [Source:HGNC Symbol;Acc:HGNC:10782]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000116761	9.261	8.907	10.735	10.971	9.488	18.46	398	387	343	352	347	581	CTH	cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism;ko00450//Selenocompound metabolism"	K01758;K01758;K01758;K01758;K01758	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004123//cystathionine gamma-lyase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0016829//lyase activity;GO:0016846//carbon-sulfur lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding;GO:0044540//L-cystine L-cysteine-lyase (deaminating);GO:0080146//L-cysteine desulfhydrase activity	GO:0006534//cysteine metabolic process;GO:0006629//lipid metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0018272//protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0019344//cysteine biosynthetic process;GO:0019346//transsulfuration;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044524//protein sulfhydration;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051289//protein homotetramerization;GO:0070814//hydrogen sulfide biosynthetic process;GO:1904831//positive regulation of aortic smooth muscle cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000116771	0.156	0.124	0.063	0.105	0.092	0.086	10	8	3	5	5	4	AGMAT	agmatinase [Source:HGNC Symbol;Acc:HGNC:18407]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K01480;K01480	GO:0005739//mitochondrion	"GO:0008783//agmatinase activity;GO:0016787//hydrolase activity;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0046872//metal ion binding"	"GO:0008295//spermidine biosynthetic process;GO:0009446//putrescine biosynthetic process;GO:0033388//putrescine biosynthetic process from arginine;GO:0033389//putrescine biosynthetic process from arginine, using agmatinase;GO:0097055//agmatine biosynthetic process;GO:1901564//organonitrogen compound metabolic process"	--
ENSG00000116774	10.494	9.812	12.221	12.33	11.872	13.706	387	367	335	335	371	367	OLFML3	olfactomedin like 3 [Source:HGNC Symbol;Acc:HGNC:24956]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:1903561//extracellular vesicle	-	GO:0007165//signal transduction	--
ENSG00000116783	0	0	0	0.13	0	0	0	0	0	6.05	0	0	TNNI3K	TNNI3 interacting kinase [Source:HGNC Symbol;Acc:HGNC:19661]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031013//troponin I binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0002027//regulation of heart rate;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0055117//regulation of cardiac muscle contraction;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:1903779//regulation of cardiac conduction	--
ENSG00000116785	0	0.016	0	0.062	0	0	0	1	0	1	0	0	CFHR3	complement factor H related 3 [Source:HGNC Symbol;Acc:HGNC:16980]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K23815	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005515//protein binding	-	--
ENSG00000116786	31.567	31.241	31.097	34.155	33.297	35.405	2644	2615	1921	2120	2367	2161	PLEKHM2	pleckstrin homology and RUN domain containing M2 [Source:HGNC Symbol;Acc:HGNC:29131]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K15348	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0007030//Golgi organization;GO:0032418//lysosome localization;GO:0032880//regulation of protein localization;GO:0042267//natural killer cell mediated cytotoxicity;GO:1903527//positive regulation of membrane tubulation	--
ENSG00000116791	38.599	34.929	39.693	33.25	30.394	39.64	1314.05	1268.07	1044.44	880	932.13	995.3	CRYZ	crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003960//NADPH:quinone reductase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0070402//NADPH binding	GO:0007601//visual perception;GO:0042178//xenobiotic catabolic process;GO:0051289//protein homotetramerization	--
ENSG00000116793	14.188	12.228	11.787	10.122	11.395	11.902	887	808	584	465	583	528	PHTF1	putative homeodomain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:8939]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	Others
ENSG00000116809	10.468	10.093	10.01	10.764	11.463	10.813	591	573	417	450	520	445	ZBTB17	zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:12936]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Cancer: overview;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04110//Cell cycle;ko05222//Small cell lung cancer	K10500;K10500;K10500;K10500	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001702//gastrulation with mouth forming second;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007398//ectoderm development;GO:0008285//negative regulation of cell population proliferation;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070314//G1 to G0 transition"	ZBTB
ENSG00000116815	4.744	3.292	3.691	3.248	3.207	3.224	104	70	62	51	59	50	CD58	CD58 molecule [Source:HGNC Symbol;Acc:HGNC:1688]	Human Diseases;Environmental Information Processing	Infectious disease: viral;Signaling molecules and interaction	ko05169//Epstein-Barr virus infection;ko04514//Cell adhesion molecules	K06492;K06492	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0032757//positive regulation of interleukin-8 production;GO:0034113//heterotypic cell-cell adhesion;GO:0071346//cellular response to interferon-gamma;GO:0071356//cellular response to tumor necrosis factor;GO:0098609//cell-cell adhesion	--
ENSG00000116819	0.021	0.021	0	0.087	0.025	0.089	1	1	0	3	1	3	TFAP2E	transcription factor AP-2 epsilon [Source:HGNC Symbol;Acc:HGNC:30774]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0042802//identical protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0042127//regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	AP-2
ENSG00000116824	0	0	0	0	0	0	0	0	0	0	0	0	CD2	CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639]	Organismal Systems;Environmental Information Processing	Immune system;Signaling molecules and interaction	ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules	K06449;K06449	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0043621//protein self-association	GO:0001766//membrane raft polarization;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0030101//natural killer cell activation;GO:0030887//positive regulation of myeloid dendritic cell activation;GO:0032729//positive regulation of interferon-gamma production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034113//heterotypic cell-cell adhesion;GO:0042110//T cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0045580//regulation of T cell differentiation;GO:0098609//cell-cell adhesion	--
ENSG00000116830	2.574	1.845	1.12	1.138	2.186	1.264	433	363	162	165	267	180	TTF2	transcription termination factor 2 [Source:HGNC Symbol;Acc:HGNC:12398]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K15173	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0006338//chromatin remodeling;GO:0006353//DNA-templated transcription, termination;GO:0006369//termination of RNA polymerase II transcription;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000116833	0	0.031	0	0	0	0	0	2	0	0	0	0	NR5A2	nuclear receptor subfamily 5 group A member 2 [Source:HGNC Symbol;Acc:HGNC:7984]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08027	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008206//bile acid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0009792//embryo development ending in birth or egg hatching;GO:0009888//tissue development;GO:0030522//intracellular receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0042127//regulation of cell population proliferation;GO:0042592//homeostatic process;GO:0042632//cholesterol homeostasis;GO:0045070//positive regulation of viral genome replication;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061113//pancreas morphogenesis;GO:0097720//calcineurin-mediated signaling;GO:1990830//cellular response to leukemia inhibitory factor"	SF-like
ENSG00000116852	37.072	36.378	39.871	32.006	37.119	36.321	6567	6510	5151	4166	5583	4634	KIF21B	kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement	--
ENSG00000116857	68.603	73.128	72.603	83.994	75.468	81.38	1724	1768	1379	1593	1588	1352	TMEM9	transmembrane protein 9 [Source:HGNC Symbol;Acc:HGNC:18823]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007042//lysosomal lumen acidification;GO:0015031//protein transport;GO:0042176//regulation of protein catabolic process;GO:0048388//endosomal lumen acidification;GO:0070070//proton-transporting V-type ATPase complex assembly;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000116863	12.732	12.87	14.431	15.454	14.482	14.849	436	443	365	392	419	370	ADPRS	ADP-ribosylserine hydrolase [Source:HGNC Symbol;Acc:HGNC:21304]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016604//nuclear body;GO:0090734//site of DNA damage	"GO:0000287//magnesium ion binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004649//poly(ADP-ribose) glycohydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0061463//O-acetyl-ADP-ribose deacetylase activity;GO:0140292//ADP-ribosylserine hydrolase activity"	"GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006974//cellular response to DNA damage stimulus;GO:0060546//negative regulation of necroptotic process;GO:0071451//cellular response to superoxide;GO:0140290//peptidyl-serine ADP-deribosylation"	--
ENSG00000116871	39.36	39.516	44.089	40.708	40.034	40.699	2623	2658	2160	1994	2221	1998	MAP7D1	MAP7 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25514]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton	-	GO:0000226//microtubule cytoskeleton organization	--
ENSG00000116874	7.602	5.984	5.522	5.136	4.522	4.726	440	348	236	220	221	199	WARS2	"tryptophanyl tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12730]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01867	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004830//tryptophan-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0001570//vasculogenesis;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0045766//positive regulation of angiogenesis;GO:0070183//mitochondrial tryptophanyl-tRNA aminoacylation	--
ENSG00000116882	0	0	0	0	0	0	0	0	0	0	0	0	HAO2	hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810]	Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Global and overview maps;Transport and catabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04146//Peroxisome;ko00630//Glyoxylate and dicarboxylate metabolism	K11517;K11517;K11517;K11517	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0003973//(S)-2-hydroxy-acid oxidase activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity	GO:0019395//fatty acid oxidation	--
ENSG00000116885	9.963	12.606	9.691	9.544	8.755	10.967	269	254	198	179	195	219	OSCP1	organic solute carrier partner 1 [Source:HGNC Symbol;Acc:HGNC:29971]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane	GO:0022857//transmembrane transporter activity	GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000116898	28.279	29.141	29.522	26.567	23.712	26.351	559	579	431	389	396	379	MRPS15	mitochondrial ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:14504]	Genetic Information Processing	Translation	ko03010//Ribosome	K02956	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000116903	2.657	2.691	2.532	2.686	2.373	2.527	281.08	286.16	197.86	210.47	212.08	194.47	EXOC8	exocyst complex component 8 [Source:HGNC Symbol;Acc:HGNC:24659]	-	-	-	-	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035091//phosphatidylinositol binding	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0007032//endosome organization;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0022617//extracellular matrix disassembly;GO:0034613//cellular protein localization;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000116906	20.738	19.832	19.288	16.711	18.151	18.347	1033	1001	743	659	746	702	GNPAT	glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416]	Metabolism;Cellular Processes	Lipid metabolism;Transport and catabolism	ko00564//Glycerophospholipid metabolism;ko04146//Peroxisome	K00649;K00649	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0110165//cellular anatomical entity	GO:0003824//catalytic activity;GO:0008374//O-acyltransferase activity;GO:0016287//glycerone-phosphate O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006631//fatty acid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007416//synapse assembly;GO:0007584//response to nutrient;GO:0008611//ether lipid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0021587//cerebellum morphogenesis;GO:0030913//paranodal junction assembly;GO:0042552//myelination;GO:0042594//response to starvation;GO:0044255//cellular lipid metabolic process;GO:0061024//membrane organization;GO:0070542//response to fatty acid	--
ENSG00000116918	13.854	11.712	13.351	9.811	12.728	11.907	756.9	628.42	501.33	382	530	457	TSNAX	translin associated factor X [Source:HGNC Symbol;Acc:HGNC:12380]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:1902555//endoribonuclease complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004521//endoribonuclease activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0007283//spermatogenesis;GO:0016246//RNA interference;GO:0030154//cell differentiation;GO:0030422//production of siRNA involved in RNA interference;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000116922	6.079	5.93	6.588	6.956	6.363	6.443	223	233	169	180	186	175	C1orf109	chromosome 1 open reading frame 109 [Source:HGNC Symbol;Acc:HGNC:26039]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000116954	15.429	14.724	14.292	15.974	15.432	15.62	858	823	587	658	725	632	RRAGC	Ras related GTP binding C [Source:HGNC Symbol;Acc:HGNC:19902]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: bacterial;Signal transduction;Transport and catabolism	ko05131//Shigellosis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K16186;K16186;K16186	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:1990131//Gtr1-Gtr2 GTPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0046982//protein heterodimerization activity;GO:0051020//GTPase binding	"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0008380//RNA splicing;GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0032006//regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0034613//cellular protein localization;GO:0043200//response to amino acid;GO:0071230//cellular response to amino acid stimulus;GO:1903432//regulation of TORC1 signaling"	--
ENSG00000116962	5.419	5.189	4.076	4.278	4.645	4.725	651	624	359	379	465	413	NID1	nidogen 1 [Source:HGNC Symbol;Acc:HGNC:7821]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0043237//laminin-1 binding;GO:0043394//proteoglycan binding;GO:0050840//extracellular matrix binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0032836//glomerular basement membrane development;GO:0045785//positive regulation of cell adhesion;GO:0051149//positive regulation of muscle cell differentiation;GO:0071711//basement membrane organization;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000116977	8.158	10.513	8.398	9.594	9.29	9.534	604.64	512.56	416.91	384.84	482.35	425.28	LGALS8	galectin 8 [Source:HGNC Symbol;Acc:HGNC:6569]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006914//autophagy;GO:0098586//cellular response to virus;GO:0098792//xenophagy;GO:1904977//lymphatic endothelial cell migration	--
ENSG00000116981	0.005	0	0	0	0	0	1	0	0	0	0	0	NT5C1A	"5'-nucleotidase, cytosolic IA [Source:HGNC Symbol;Acc:HGNC:17819]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0050483//IMP 5'-nucleotidase activity	GO:0000255//allantoin metabolic process;GO:0006196//AMP catabolic process;GO:0006204//IMP catabolic process;GO:0009116//nucleoside metabolic process;GO:0009117//nucleotide metabolic process;GO:0009128//purine nucleoside monophosphate catabolic process;GO:0016311//dephosphorylation;GO:0046055//dGMP catabolic process;GO:0046059//dAMP catabolic process;GO:0046085//adenosine metabolic process	--
ENSG00000116983	0	0.011	0	0	0	0	0	1	0	0	0	0	HPCAL4	hippocalcin like 4 [Source:HGNC Symbol;Acc:HGNC:18212]	-	-	-	-	-	GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007417//central nervous system development	--
ENSG00000116984	8.033	8.34	6.904	5.117	6.548	5.139	1299	1174	823	573	819	586	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Metabolism of cofactors and vitamins;Metabolism of other amino acids	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00670//One carbon pool by folate;ko00450//Selenocompound metabolism	K00548;K00548;K00548;K00548;K00548	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008172//S-methyltransferase activity;GO:0008270//zinc ion binding;GO:0008705//methionine synthase activity;GO:0016740//transferase activity;GO:0031419//cobalamin binding;GO:0046872//metal ion binding	GO:0007399//nervous system development;GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0009235//cobalamin metabolic process;GO:0031103//axon regeneration;GO:0032259//methylation;GO:0042558//pteridine-containing compound metabolic process;GO:0044237//cellular metabolic process;GO:0048678//response to axon injury;GO:0071704//organic substance metabolic process;GO:0071732//cellular response to nitric oxide	--
ENSG00000116985	1.88	2.155	1.825	3.047	3.086	2.622	188.18	216.84	134.93	225.96	261	191	BMP8B	bone morphogenetic protein 8b [Source:HGNC Symbol;Acc:HGNC:1075]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Environmental adaptation;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04714//Thermogenesis;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K16622;K16622;K16622;K16622	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070700//BMP receptor binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0051216//cartilage development;GO:0060395//SMAD protein signal transduction	--
ENSG00000116990	3.985	4.602	4.896	4.754	4.205	4.578	252	303	243	227	237	211	MYCL	"MYCL proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7555]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045607//regulation of inner ear auditory receptor cell differentiation"	bHLH
ENSG00000116991	2.885	2.96	2.444	2.033	2.627	2.753	409	420	250	209	297	253	SIPA1L2	signal induced proliferation associated 1 like 2 [Source:HGNC Symbol;Acc:HGNC:23800]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17702	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0008150//biological_process;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000116996	0	0	0	0	0	0	0	0	0	0	0	0	ZP4	zona pellucida glycoprotein 4 [Source:HGNC Symbol;Acc:HGNC:15770]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035805//egg coat;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0032190//acrosin binding;GO:0035804//structural constituent of egg coat;GO:0042802//identical protein binding	GO:0002922//positive regulation of humoral immune response;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0042102//positive regulation of T cell proliferation;GO:0060468//prevention of polyspermy;GO:0060478//acrosomal vesicle exocytosis;GO:2000344//positive regulation of acrosome reaction;GO:2000360//negative regulation of binding of sperm to zona pellucida	--
ENSG00000117000	7.775	5.341	4.399	3.843	3.928	3.955	1005	694	420	368	429	372	RLF	RLF zinc finger [Source:HGNC Symbol;Acc:HGNC:10025]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0044030//regulation of DNA methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097692//histone H3-K4 monomethylation"	zf-C2H2
ENSG00000117009	0.751	0.469	0.413	1.645	2.232	0.424	55.3	36.2	28.07	87.81	56.94	32.09	KMO	kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K00486;K00486	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004497//monooxygenase activity;GO:0004502//kynurenine 3-monooxygenase activity;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding	"GO:0006569//tryptophan catabolic process;GO:0007568//aging;GO:0009435//NAD biosynthetic process;GO:0009651//response to salt stress;GO:0014049//positive regulation of glutamate secretion;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019674//NAD metabolic process;GO:0019805//quinolinate biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0034276//kynurenic acid biosynthetic process;GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0043420//anthranilate metabolic process;GO:0070189//kynurenine metabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0097052//L-kynurenine metabolic process;GO:1901216//positive regulation of neuron death;GO:1903296//positive regulation of glutamate secretion, neurotransmission"	--
ENSG00000117010	1.616	1.235	1.117	1.23	1.4	1.647	63	52	35	37	50	49	ZNF684	zinc finger protein 684 [Source:HGNC Symbol;Acc:HGNC:28418]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000117013	13.123	12.584	13.27	12.584	13.237	14.723	1177	1123	879	836	1003	951	KCNQ4	potassium voltage-gated channel subfamily Q member 4 [Source:HGNC Symbol;Acc:HGNC:6298]	Organismal Systems	Nervous system	ko04725//Cholinergic synapse	K04929	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007605//sensory perception of sound;GO:0034765//regulation of ion transmembrane transport;GO:0042472//inner ear morphogenesis;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000117016	2.975	3.218	3.768	2.518	4.295	3.083	448	487	365	262	406	327	RIMS3	regulating synaptic membrane exocytosis 3 [Source:HGNC Symbol;Acc:HGNC:21292]	-	-	-	-	GO:0016020//membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0017156//calcium-ion regulated exocytosis;GO:0042391//regulation of membrane potential;GO:0048167//regulation of synaptic plasticity;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0050806//positive regulation of synaptic transmission;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000117020	17.756	13.624	14.569	11.539	12.794	12.438	2277.8	1844.06	1319.63	980.5	1264.14	1116.12	AKT3	AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Circulatory system;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Signal transduction;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Endocrine system;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Digestive system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04973//Carbohydrate digestion and absorption"	K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000002//mitochondrial genome maintenance;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032008//positive regulation of TOR signaling;GO:0035556//intracellular signal transduction;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0045793//positive regulation of cell size;GO:0048854//brain morphogenesis;GO:0048873//homeostasis of number of cells within a tissue;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1905653//positive regulation of artery morphogenesis;GO:2000773//negative regulation of cellular senescence	--
ENSG00000117036	2.625	2.817	3.732	2.094	2.766	3.588	273	303	280	166	241	286	ETV3	ETS variant transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3492]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0090571//RNA polymerase II transcription repressor complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0017151//DEAD/H-box RNA helicase binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus"	ETS
ENSG00000117054	28.211	25.104	26.353	22.704	22.079	27.712	1067	957	775	655	729	785	ACADM	acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Global and overview maps;Amino acid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation"	K00249;K00249;K00249;K00249;K00249;K00249	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030424//axon;GO:0031966//mitochondrial membrane	"GO:0003995//acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity"	"GO:0001889//liver development;GO:0005978//glycogen biosynthetic process;GO:0006082//organic acid metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0007507//heart development;GO:0009409//response to cold;GO:0009437//carnitine metabolic process;GO:0009791//post-embryonic development;GO:0019254//carnitine metabolic process, CoA-linked;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0042594//response to starvation;GO:0045329//carnitine biosynthetic process;GO:0051791//medium-chain fatty acid metabolic process;GO:0051793//medium-chain fatty acid catabolic process;GO:0055007//cardiac muscle cell differentiation"	--
ENSG00000117069	2.211	2.468	1.244	0.536	1.143	0.452	167	165	64	26	55	25	ST6GALNAC5	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:19342]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03375;K03375	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0097503//sialylation	--
ENSG00000117090	0	0	0	0	0	0	0	0	0	0	0	0	SLAMF1	signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903]	Human Diseases	Infectious disease: viral	ko05162//Measles	K06536	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0003823//antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding	GO:0001779//natural killer cell differentiation;GO:0001787//natural killer cell proliferation;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002250//adaptive immune response;GO:0002277//myeloid dendritic cell activation involved in immune response;GO:0002376//immune system process;GO:0002725//negative regulation of T cell cytokine production;GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0008284//positive regulation of cell population proliferation;GO:0010759//positive regulation of macrophage chemotaxis;GO:0031338//regulation of vesicle fusion;GO:0032689//negative regulation of interferon-gamma production;GO:0032695//negative regulation of interleukin-12 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0046649//lymphocyte activation;GO:0046718//viral entry into host cell;GO:0050790//regulation of catalytic activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000349//negative regulation of CD40 signaling pathway;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:2000556//positive regulation of T-helper 1 cell cytokine production	--
ENSG00000117091	0	0	0	0	0	0	0	0	0	0	0	0	CD48	CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K06479	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002819//regulation of adaptive immune response;GO:0006952//defense response;GO:0042110//T cell activation	--
ENSG00000117114	6.693	5.29	5.689	5.656	5.888	6.249	767	609	487	478	580	528	ADGRL2	adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0016524//latrotoxin receptor activity;GO:0030246//carbohydrate binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0009617//response to bacterium;GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly	--
ENSG00000117115	22.464	21.799	22.079	25.655	25.019	21.879	2032	1982	1453	1719	1912	1440	PADI2	peptidyl arginine deiminase 2 [Source:HGNC Symbol;Acc:HGNC:18341]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0030331//estrogen receptor binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0010848//regulation of chromatin disassembly;GO:0018101//protein citrullination;GO:0021762//substantia nigra development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0036413//histone H3-R26 citrullination;GO:0036414//histone citrullination;GO:0045815//positive regulation of gene expression, epigenetic;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:1901624//negative regulation of lymphocyte chemotaxis;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000117118	33.439	32.176	31.385	31.229	31.484	36.035	704	661	488	487	560	552	SDHB	succinate dehydrogenase complex iron sulfur subunit B [Source:HGNC Symbol;Acc:HGNC:10681]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235;K00235	"GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0045273//respiratory chain complex II"	"GO:0005515//protein binding;GO:0008177//succinate dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0048039//ubiquinone binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006099//tricarboxylic acid cycle;GO:0006105//succinate metabolic process;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000117122	153.929	169.119	148.366	109.473	116.201	102.107	3333	3678	2368	1755	2122	1606	MFAP2	microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0048048//embryonic eye morphogenesis;GO:0048050//post-embryonic eye morphogenesis;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000117133	11.862	11.519	9.282	8.453	9.089	8.64	453	429	277	253	306	254	RPF1	ribosome production factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:30350]	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0042134//rRNA primary transcript binding	GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000117139	31.276	33.557	32.993	23.525	26.456	26.158	4057	4373	3177	2238	2882	2444	KDM5B	lysine demethylase 5B [Source:HGNC Symbol;Acc:HGNC:18039]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0034647//histone H3-tri/di/monomethyl-lysine-4 demethylase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007338//single fertilization;GO:0009791//post-embryonic development;GO:0010628//positive regulation of gene expression;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0034720//histone H3-K4 demethylation;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060763//mammary duct terminal end bud growth;GO:0060992//response to fungicide;GO:0061038//uterus morphogenesis;GO:0070076//histone lysine demethylation;GO:0070306//lens fiber cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000864//regulation of estradiol secretion"	--
ENSG00000117143	8.375	7.09	7.264	5.17	6.061	5.163	611	521	392	279	374	274	UAP1	UDP-N-acetylglucosamine pyrophosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12457]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K00972;K00972	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003977//UDP-N-acetylglucosamine diphosphorylase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042802//identical protein binding;GO:0052630//UDP-N-acetylgalactosamine diphosphorylase activity;GO:0070569//uridylyltransferase activity	GO:0006048//UDP-N-acetylglucosamine biosynthetic process	--
ENSG00000117148	0	0	0	0	0	0.079	0	0	0	0	0	2	ACTL8	actin like 8 [Source:HGNC Symbol;Acc:HGNC:24018]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005869//dynactin complex	GO:0005515//protein binding	GO:0030855//epithelial cell differentiation	--
ENSG00000117151	26.12	22.888	23.908	18.37	18.532	22.707	1566	1358	952	794	882	940	CTBS	chitobiase [Source:HGNC Symbol;Acc:HGNC:2496]	-	-	-	-	GO:0005615//extracellular space;GO:0005764//lysosome	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004568//chitinase activity;GO:0008061//chitin binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process	--
ENSG00000117152	44.641	42.718	21.315	10.805	13.486	7.124	1274	1304	442	273	358	201	RGS4	regulator of G protein signaling 4 [Source:HGNC Symbol;Acc:HGNC:10000]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005516//calmodulin binding	GO:0001975//response to amphetamine;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0010460//positive regulation of heart rate;GO:0042220//response to cocaine;GO:0043278//response to morphine;GO:0043547//positive regulation of GTPase activity;GO:0045471//response to ethanol;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051924//regulation of calcium ion transport;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0110053//regulation of actin filament organization;GO:1900924//negative regulation of glycine import across plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1990791//dorsal root ganglion development;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000117153	8.4	8.937	9.363	9.078	9.228	9.867	572	598	469	440	465	491	KLHL12	kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360]	-	-	-	-	GO:0005829//cytosol;GO:0030127//COPII vesicle coat;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006513//protein monoubiquitination;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0014029//neural crest formation;GO:0014032//neural crest cell development;GO:0016055//Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0016567//protein ubiquitination;GO:0048208//COPII vesicle coating	--
ENSG00000117154	0.994	0.887	1.104	1.858	1.418	1.226	39	35	32	54	47	35	IGSF21	immunoglobin superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:28246]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse	-	GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0060074//synapse maturation	--
ENSG00000117155	24.959	18.582	19.576	14.297	16.538	17.456	1834	1382	1063	760	983	918	SSX2IP	SSX family member 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:16509]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K06085	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0007098//centrosome cycle;GO:0007155//cell adhesion;GO:0030030//cell projection organization;GO:0035020//regulation of Rac protein signal transduction;GO:0035735//intraciliary transport involved in cilium assembly;GO:0060271//cilium assembly;GO:2000145//regulation of cell motility	--
ENSG00000117174	2.355	2.173	2.147	2.182	2.033	1.859	303	281	204	208	221	174	ZNHIT6	zinc finger HIT-type containing 6 [Source:HGNC Symbol;Acc:HGNC:26089]	-	-	-	-	GO:0005634//nucleus;GO:0070062//extracellular exosome;GO:0070761//pre-snoRNP complex	GO:0001094//TFIID-class transcription factor complex binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000492//box C/D snoRNP assembly;GO:0042254//ribosome biogenesis;GO:0048254//snoRNA localization;GO:0051259//protein complex oligomerization"	--
ENSG00000117215	0	0	0	0	0	0	0	0	0	0	0	0	PLA2G2D	phospholipase A2 group IID [Source:HGNC Symbol;Acc:HGNC:9033]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	"GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0002864//regulation of acute inflammatory response to antigenic stimulus;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response;GO:0016042//lipid catabolic process;GO:0042130//negative regulation of T cell proliferation;GO:0046337//phosphatidylethanolamine metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0050482//arachidonic acid secretion;GO:0050868//negative regulation of T cell activation"	--
ENSG00000117222	6.482	6.548	6.277	5.912	5.541	6.773	585	593	418	395	422	445	RBBP5	"RB binding protein 5, histone lysine methyltransferase complex subunit [Source:HGNC Symbol;Acc:HGNC:9888]"	Human Diseases	Endocrine and metabolic disease	ko04934//Cushing syndrome	K14961	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex	GO:0000976//transcription cis-regulatory region binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific)	GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0043627//response to estrogen;GO:0051568//histone H3-K4 methylation	--
ENSG00000117226	2.659	2.708	2.826	1.658	2.642	1.178	156	156	77	69	97	54	GBP3	guanylate binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4184]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20899	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0002376//immune system process;GO:0051607//defense response to virus;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000117228	2.949	3.022	2.561	3.118	3.28	2.296	154	166	96	124	145	89	GBP1	guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20899	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0019899//enzyme binding;GO:0019955//cytokine binding;GO:0030507//spectrin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051879//Hsp90 protein binding	GO:0002376//immune system process;GO:0032703//negative regulation of interleukin-2 production;GO:0050848//regulation of calcium-mediated signaling;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051607//defense response to virus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0072665//protein localization to vacuole;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1903076//regulation of protein localization to plasma membrane;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000117245	0.11	0.162	0.164	0.219	0.115	0.185	9	13	9	12	8	10	KIF17	kinesin family member 17 [Source:HGNC Symbol;Acc:HGNC:19167]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0030425//dendrite;GO:0032391//photoreceptor connecting cilium;GO:0032839//dendrite cytoplasm;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043005//neuron projection;GO:1990075//periciliary membrane compartment	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity	GO:0007017//microtubule-based process;GO:0007018//microtubule-based movement;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0031503//protein-containing complex localization;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex	--
ENSG00000117262	13.947	15.59	15.77	9.621	12.225	13.154	552.56	575.25	440.19	301.37	418.02	367.15	GPR89A	G protein-coupled receptor 89A [Source:HGNC Symbol;Acc:HGNC:31984]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0032580//Golgi cisterna membrane	GO:0005244//voltage-gated ion channel activity;GO:0008308//voltage-gated anion channel activity	GO:0006811//ion transport;GO:0015031//protein transport;GO:0015698//inorganic anion transport;GO:0030217//T cell differentiation;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051452//intracellular pH reduction	--
ENSG00000117266	52.836	56.048	48.089	63.038	64.51	62.546	3277	3506	2178	2853	3374	2782	CDK18	cyclin dependent kinase 18 [Source:HGNC Symbol;Acc:HGNC:8751]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000117280	20.561	19.247	19.531	17.249	19.437	27.482	1013	1000	716	706	777	976	RAB29	"RAB29, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9789]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005773//vacuole;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031982//vesicle;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0097708//intracellular vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0019894//kinesin binding;GO:0031267//small GTPase binding;GO:0070840//dynein complex binding	"GO:0001921//positive regulation of receptor recycling;GO:0006886//intracellular protein transport;GO:0007005//mitochondrion organization;GO:0007030//Golgi organization;GO:0007416//synapse assembly;GO:0009617//response to bacterium;GO:0010977//negative regulation of neuron projection development;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0032438//melanosome organization;GO:0039694//viral RNA genome replication;GO:0042110//T cell activation;GO:0042147//retrograde transport, endosome to Golgi;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0072657//protein localization to membrane;GO:0090316//positive regulation of intracellular protein transport;GO:1901214//regulation of neuron death;GO:1901998//toxin transport;GO:1903441//protein localization to ciliary membrane;GO:1905279//regulation of retrograde transport, endosome to Golgi"	--
ENSG00000117281	0.257	0.014	0.019	0.185	0.051	0.115	12	1	1	4.06	3	3	CD160	CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0023024//MHC class I protein complex binding;GO:0032393//MHC class I receptor activity;GO:0032394//MHC class Ib receptor activity;GO:0032397//activating MHC class I receptor activity	"GO:0001525//angiogenesis;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002385//mucosal immune response;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0002819//regulation of adaptive immune response;GO:0002857//positive regulation of natural killer cell mediated immune response to tumor cell;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016525//negative regulation of angiogenesis;GO:0031295//T cell costimulation;GO:0032729//positive regulation of interferon-gamma production;GO:0043323//positive regulation of natural killer cell degranulation;GO:0045087//innate immune response;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050829//defense response to Gram-negative bacterium;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:1900280//negative regulation of CD4-positive, alpha-beta T cell costimulation;GO:1905675//negative regulation of adaptive immune memory response;GO:2000353//positive regulation of endothelial cell apoptotic process"	--
ENSG00000117298	3.718	4.518	3.294	2.284	2.514	2.027	336	408	249	161	190	147	ECE1	endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031302//intrinsic component of endosome membrane;GO:0031982//vesicle;GO:0033093//Weibel-Palade body;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0017046//peptide hormone binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001921//positive regulation of receptor recycling;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0006508//proteolysis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007507//heart development;GO:0010467//gene expression;GO:0010814//substance P catabolic process;GO:0010815//bradykinin catabolic process;GO:0010816//calcitonin catabolic process;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0019229//regulation of vasoconstriction;GO:0031175//neuron projection development;GO:0034959//endothelin maturation;GO:0035050//embryonic heart tube development;GO:0042447//hormone catabolic process;GO:0042733//embryonic digit morphogenesis;GO:0043583//ear development;GO:0060037//pharyngeal system development;GO:0060385//axonogenesis involved in innervation;GO:0097492//sympathetic neuron axon guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000117305	21.31	24.367	24.317	25.634	21.175	22.569	692	791	579	614	580	524	HMGCL	3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism"	K01640;K01640;K01640;K01640	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004419//hydroxymethylglutaryl-CoA lyase activity;GO:0005198//structural molecule activity;GO:0016829//lyase activity;GO:0016833//oxo-acid-lyase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0006552//leucine catabolic process;GO:0006629//lipid metabolic process;GO:0007005//mitochondrion organization;GO:0046951//ketone body biosynthetic process	--
ENSG00000117308	18.119	20.278	21.012	28.401	25.637	26.125	461	516	393	547	541	464	GALE	UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00052//Galactose metabolism	K01784;K01784;K01784	GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0003974//UDP-N-acetylglucosamine 4-epimerase activity;GO:0003978//UDP-glucose 4-epimerase activity;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0005975//carbohydrate metabolic process;GO:0006012//galactose metabolic process;GO:0019388//galactose catabolic process;GO:0033499//galactose catabolic process via UDP-galactose	--
ENSG00000117318	41.157	43.976	61.429	52.686	48.956	51.474	811	871	894	769	815	738	ID3	"inhibitor of DNA binding 3, HLH protein [Source:HGNC Symbol;Acc:HGNC:5362]"	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K17694;K17694	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043425//bHLH transcription factor binding;GO:0046983//protein dimerization activity;GO:0140416//transcription regulator inhibitor activity;GO:1901707//leptomycin B binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0006275//regulation of DNA replication;GO:0007275//multicellular organism development;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007623//circadian rhythm;GO:0009611//response to wounding;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030855//epithelial cell differentiation;GO:0030903//notochord development;GO:0032922//circadian regulation of gene expression;GO:0042476//odontogenesis;GO:0043065//positive regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045662//negative regulation of myoblast differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle;GO:0072750//cellular response to leptomycin B"	bHLH
ENSG00000117322	0.14	0.164	0.034	0.256	0.263	0.114	12	14	2	16	19	7	CR2	complement C3d receptor 2 [Source:HGNC Symbol;Acc:HGNC:2336]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Immune system;Immune system	ko05169//Epstein-Barr virus infection;ko04640//Hematopoietic cell lineage;ko04662//B cell receptor signaling pathway;ko04610//Complement and coagulation cascades	K04012;K04012;K04012;K04012	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0001848//complement binding;GO:0003677//DNA binding;GO:0004875//complement receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	"GO:0002376//immune system process;GO:0002430//complement receptor mediated signaling pathway;GO:0006955//immune response;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0030183//B cell differentiation;GO:0042100//B cell proliferation;GO:0045087//innate immune response;GO:0045959//negative regulation of complement activation, classical pathway;GO:0046718//viral entry into host cell"	--
ENSG00000117335	38.478	35.27	42.88	39.02	37.97	47.823	2567	2337	2118	1908	2136	2268	CD46	CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05162//Measles;ko04610//Complement and coagulation cascades	K04007;K04007	GO:0002079//inner acrosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0045296//cadherin binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0006958//complement activation, classical pathway;GO:0007338//single fertilization;GO:0008593//regulation of Notch signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032733//positive regulation of interleukin-10 production;GO:0035581//sequestering of extracellular ligand from receptor;GO:0042102//positive regulation of T cell proliferation;GO:0043382//positive regulation of memory T cell differentiation;GO:0045087//innate immune response;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0046718//viral entry into host cell;GO:0071636//positive regulation of transforming growth factor beta production"	--
ENSG00000117360	10.924	10.471	11.898	9.356	11.229	11.72	547	527	440	347	475	427	PRPF3	pre-mRNA processing factor 3 [Source:HGNC Symbol;Acc:HGNC:17348]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12843	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000117362	71.123	76.547	75.45	85.735	79.872	78.973	3120	3365	2440	2796	2966	2542	APH1A	"aph-1 homolog A, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:29509]"	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05010//Alzheimer disease;ko04330//Notch signaling pathway	K06172;K06172	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070765//gamma-secretase complex;GO:0097060//synaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030674//protein-macromolecule adaptor activity;GO:0061133//endopeptidase activator activity	GO:0001656//metanephros development;GO:0006509//membrane protein ectodomain proteolysis;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0010950//positive regulation of endopeptidase activity;GO:0016485//protein processing;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034205//amyloid-beta formation;GO:0042982//amyloid precursor protein metabolic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity	--
ENSG00000117385	62.274	69.768	66.438	66.708	64.293	65.269	3373	3786	2658	2669	2935	2563	P3H1	prolyl 3-hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:19316]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	"GO:0003674//molecular_function;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006457//protein folding;GO:0008285//negative regulation of cell population proliferation;GO:0010976//positive regulation of neuron projection development;GO:0018126//protein hydroxylation;GO:0019511//peptidyl-proline hydroxylation;GO:0032963//collagen metabolic process;GO:0050708//regulation of protein secretion;GO:0050821//protein stabilization;GO:0060348//bone development;GO:0061077//chaperone-mediated protein folding;GO:1901874//negative regulation of post-translational protein modification	--
ENSG00000117394	1752.583	1805.244	1736.798	1902.161	1959.776	1731.856	97666	103889	71381	78132	95647	71430	SLC2A1	solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Infectious disease: viral;Cardiovascular disease;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Digestive system;Endocrine system;Cancer: specific types;Cancer: overview;Endocrine system	ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko04919//Thyroid hormone signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04976//Bile secretion;ko04911//Insulin secretion;ko05211//Renal cell carcinoma;ko05230//Central carbon metabolism in cancer;ko04920//Adipocytokine signaling pathway	K07299;K07299;K07299;K07299;K07299;K07299;K07299;K07299;K07299;K07299;K07299;K07299	GO:0000139//Golgi membrane;GO:0001917//photoreceptor inner segment;GO:0001939//female pronucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005911//cell-cell junction;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0030496//midbody;GO:0030864//cortical actin cytoskeleton;GO:0031982//vesicle;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098793//presynapse	GO:0005324//long-chain fatty acid transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0015149//hexose transmembrane transporter activity;GO:0019900//kinase binding;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0042802//identical protein binding;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043621//protein self-association;GO:0055056//D-glucose transmembrane transporter activity	GO:0001666//response to hypoxia;GO:0006970//response to osmotic stress;GO:0007417//central nervous system development;GO:0007565//female pregnancy;GO:0008643//carbohydrate transport;GO:0015749//monosaccharide transmembrane transport;GO:0015911//long-chain fatty acid import across plasma membrane;GO:0019852//L-ascorbic acid metabolic process;GO:0021987//cerebral cortex development;GO:0032868//response to insulin;GO:0042149//cellular response to glucose starvation;GO:0042908//xenobiotic transport;GO:0045494//photoreceptor cell maintenance;GO:0046323//glucose import;GO:0055085//transmembrane transport;GO:0065003//protein-containing complex assembly;GO:0070837//dehydroascorbic acid transport;GO:0071260//cellular response to mechanical stimulus;GO:0071474//cellular hyperosmotic response;GO:0098708//glucose import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1904016//response to Thyroglobulin triiodothyronine;GO:1904659//glucose transmembrane transport	--
ENSG00000117395	24.18	24.261	18.888	17.811	19.078	17.024	679	687	393	371	452	348	EBNA1BP2	EBNA1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15531]	-	-	-	-	"GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0034399//nuclear periphery"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000117399	2.076	1.726	2.058	1.618	1.523	1.406	71	60	52	41	44	35	CDC20	cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723]	Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes	"Infectious disease: viral;Cancer: overview;Folding, sorting and degradation;Cell growth and death;Cell growth and death"	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle	K03363;K03363;K03363;K03363;K03363	GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex;GO:0033597//mitotic checkpoint complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0010997//anaphase-promoting complex binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0097027//ubiquitin-protein transferase activator activity;GO:1990757//ubiquitin ligase activator activity	GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007346//regulation of mitotic cell cycle;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031915//positive regulation of synaptic plasticity;GO:0040020//regulation of meiotic nuclear division;GO:0050773//regulation of dendrite development;GO:0051301//cell division;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051445//regulation of meiotic cell cycle;GO:0090129//positive regulation of synapse maturation;GO:0090307//mitotic spindle assembly;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:1905786//positive regulation of anaphase-promoting complex-dependent catabolic process	--
ENSG00000117400	0.106	0	0.036	0.197	0.031	0	8	0	2	11	2	0	MPL	"MPL proto-oncogene, thrombopoietin receptor [Source:HGNC Symbol;Acc:HGNC:7217]"	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05082;K05082	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0038164//thrombopoietin receptor activity	GO:0001780//neutrophil homeostasis;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0030097//hemopoiesis;GO:0035702//monocyte homeostasis;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0050671//positive regulation of lymphocyte proliferation;GO:0070527//platelet aggregation;GO:0071456//cellular response to hypoxia;GO:1905221//positive regulation of platelet formation;GO:1990959//eosinophil homeostasis;GO:1990960//basophil homeostasis	--
ENSG00000117407	0.037	0	0.2	0	0.088	0	1	0	4	0	2	0	ARTN	artemin [Source:HGNC Symbol;Acc:HGNC:727]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030116//glial cell-derived neurotrophic factor receptor binding;GO:0030971//receptor tyrosine kinase binding	GO:0007165//signal transduction;GO:0007405//neuroblast proliferation;GO:0007411//axon guidance;GO:0007422//peripheral nervous system development;GO:0050930//induction of positive chemotaxis;GO:0061146//Peyer's patch morphogenesis;GO:0097021//lymphocyte migration into lymphoid organs	--
ENSG00000117408	22.868	22.976	23.956	24.245	25.255	23.446	1813	1860	1425	1433	1714	1374	IPO13	importin 13 [Source:HGNC Symbol;Acc:HGNC:16853]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K25202	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000117410	80.76	76.446	85.775	103.161	87.159	100.858	1726	1627	1366	1624	1575	1574	ATP6V0B	ATPase H+ transporting V0 subunit b [Source:HGNC Symbol;Acc:HGNC:861]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection	K03661;K03661;K03661;K03661;K03661;K03661;K03661;K03661;K03661;K03661	"GO:0000139//Golgi membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033179//proton-transporting V-type ATPase, V0 domain"	"GO:0005215//transporter activity;GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0016241//regulation of macroautophagy;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000117411	17.597	16.082	17.224	16.029	15.735	16.228	775	721	577	525	597	514	B4GALT2	"beta-1,4-galactosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:925]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00514//Other types of O-glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis;ko00052//Galactose metabolism;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K07967;K07967;K07967;K07967;K07967;K07967;K07967;K07967	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment;GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0098588//bounding membrane of organelle;GO:0098791//Golgi apparatus subcompartment	"GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0004461//lactose synthase activity;GO:0008378//galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0007420//brain development;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0008542//visual learning;GO:0021680//cerebellar Purkinje cell layer development;GO:0070085//glycosylation;GO:1901137//carbohydrate derivative biosynthetic process	--
ENSG00000117419	31.891	27.603	31.563	33.081	30.422	30.22	1074	988	760	859	896	782	ERI3	ERI1 exoribonuclease family member 3 [Source:HGNC Symbol;Acc:HGNC:17276]	-	-	-	-	-	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000117425	0.077	0.109	0.178	0.162	0.259	0.21	7	10	12	11	20	14	PTCH2	patched 2 [Source:HGNC Symbol;Acc:HGNC:9586]	Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K11101;K11101;K11101	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005119//smoothened binding;GO:0008158//hedgehog receptor activity;GO:0097108//hedgehog family protein binding	GO:0001558//regulation of cell growth;GO:0001709//cell fate determination;GO:0007224//smoothened signaling pathway;GO:0008544//epidermis development;GO:0009957//epidermal cell fate specification;GO:0042633//hair cycle;GO:0043588//skin development;GO:0045606//positive regulation of epidermal cell differentiation;GO:0045879//negative regulation of smoothened signaling pathway	--
ENSG00000117448	49.819	53.307	60.203	47.244	44.966	49.264	1327	1454	1183	940	1014	968	AKR1A1	aldo-keto reductase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:380]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Carbohydrate metabolism;Lipid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00010//Glycolysis / Gluconeogenesis;ko00561//Glycerolipid metabolism;ko00620//Pyruvate metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00002;K00002;K00002;K00002;K00002;K00002;K00002	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0045202//synapse;GO:0070062//extracellular exosome	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0005515//protein binding;GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0016491//oxidoreductase activity;GO:0047655//allyl-alcohol dehydrogenase activity;GO:0047939//L-glucuronate reductase activity;GO:0047941//glucuronolactone reductase activity;GO:0047956//glycerol dehydrogenase [NADP+] activity;GO:1990002//methylglyoxal reductase (NADPH-dependent, acetol producing)"	GO:0006629//lipid metabolic process;GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0019853//L-ascorbic acid biosynthetic process;GO:0042840//D-glucuronate catabolic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0046185//aldehyde catabolic process;GO:0110095//cellular detoxification of aldehyde;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000117450	406.775	397.632	387.324	365.558	353.474	356.74	7993.85	7849.47	5616.92	5318.29	5862.99	5100.65	PRDX1	peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352]	Human Diseases;Cellular Processes	Infectious disease: parasitic;Transport and catabolism	ko05146//Amoebiasis;ko04146//Peroxisome	K13279;K13279	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051920//peroxiredoxin activity	GO:0000302//response to reactive oxygen species;GO:0001501//skeletal system development;GO:0001895//retina homeostasis;GO:0006979//response to oxidative stress;GO:0008283//cell population proliferation;GO:0019430//removal of superoxide radicals;GO:0030101//natural killer cell activation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0034101//erythrocyte homeostasis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042744//hydrogen peroxide catabolic process;GO:0045321//leukocyte activation;GO:0045454//cell redox homeostasis;GO:0098869//cellular oxidant detoxification;GO:1901222//regulation of NIK/NF-kappaB signaling	--
ENSG00000117461	10.195	8.64	10.008	11.179	9.653	12.256	1095	917	749	902	918	933	PIK3R3	phosphoinositide-3-kinase regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:8981]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649	"GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA"	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006955//immune response;GO:0008286//insulin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030335//positive regulation of cell migration;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043491//protein kinase B signaling;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:2000811//negative regulation of anoikis	--
ENSG00000117472	0.804	0.652	0.927	1.246	0.634	1.31	27	22	23	31	18	32	TSPAN1	tetraspanin 1 [Source:HGNC Symbol;Acc:HGNC:20657]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0050821//protein stabilization	--
ENSG00000117475	7.099	6.815	5.16	4.379	5.238	5.286	360	340	192	169	218	199	BLZF1	basic leucine zipper nuclear factor 1 [Source:HGNC Symbol;Acc:HGNC:1065]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding	GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0043001//Golgi to plasma membrane protein transport	Others
ENSG00000117477	2.288	1.949	2.225	1.053	1.37	1.461	87	70	50	31	46	42	CCDC181	coiled-coil domain containing 181 [Source:HGNC Symbol;Acc:HGNC:28051]	-	-	-	-	GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0008017//microtubule binding	-	--
ENSG00000117479	9.196	8.053	8.554	7.424	8.436	8.053	689	603	472	412	534	439	SLC19A2	solute carrier family 19 member 2 [Source:HGNC Symbol;Acc:HGNC:10938]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14610	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008517//folic acid transmembrane transporter activity;GO:0015234//thiamine transmembrane transporter activity;GO:0090482//vitamin transmembrane transporter activity	GO:0015884//folic acid transport;GO:0015888//thiamine transport;GO:0035461//vitamin transmembrane transport;GO:0042723//thiamine-containing compound metabolic process;GO:0051180//vitamin transport;GO:0055085//transmembrane transport;GO:0071934//thiamine transmembrane transport	--
ENSG00000117480	14.762	16.803	15.972	19.65	17.327	17.187	615	711	498	604	613	528	FAAH	fatty acid amide hydrolase [Source:HGNC Symbol;Acc:HGNC:3553]	Organismal Systems	Nervous system	ko04723//Retrograde endocannabinoid signaling	K15528	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031090//organelle membrane	"GO:0004040//amidase activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0017064//fatty acid amide hydrolase activity;GO:0042802//identical protein binding;GO:0047372//acylglycerol lipase activity;GO:0102077//oleamide hydrolase activity;GO:0103073//anandamide amidohydrolase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0045907//positive regulation of vasoconstriction;GO:0052651//monoacylglycerol catabolic process	--
ENSG00000117481	5.692	5.057	6.767	4.147	5.19	5.687	376	369	335	265	343	320	NSUN4	NOP2/Sun RNA methyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:31802]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009383//rRNA (cytosine-C5-)-methyltransferase activity;GO:0016740//transferase activity;GO:0019843//rRNA binding	GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0042254//ribosome biogenesis	--
ENSG00000117500	56.567	40.266	38.019	38.37	38.435	48.11	4278.6	3028.7	2362	2006	2331	2652	TMED5	transmembrane p24 trafficking protein 5 [Source:HGNC Symbol;Acc:HGNC:24251]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0090161//Golgi ribbon formation	--
ENSG00000117501	0.022	0	0	0	0	0.021	1	0	0	0	0	1	MROH9	maestro heat like repeat family member 9 [Source:HGNC Symbol;Acc:HGNC:26287]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000117505	19.866	14.526	16.869	15.059	15.508	14.912	1372	1040	929.34	787	905	811	DR1	down-regulator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:3017]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017054//negative cofactor 2 complex;GO:0072686//mitotic spindle;GO:0090575//RNA polymerase II transcription regulator complex;GO:0140672//ATAC complex	GO:0001046//core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity;GO:0140223//general transcription initiation factor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0031063//regulation of histone deacetylation;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000117519	163.288	176.339	169.89	149.413	149.296	171.891	6510	6884	5053	4379	4963	4928	CNN3	calponin 3 [Source:HGNC Symbol;Acc:HGNC:2157]	-	-	-	-	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0030855//epithelial cell differentiation;GO:0031032//actomyosin structure organization;GO:0098609//cell-cell adhesion	--
ENSG00000117523	9.467	7.215	6.504	3.752	5.643	6.234	1645	1307	923	579	874	856	PRRC2C	proline rich coiled-coil 2C [Source:HGNC Symbol;Acc:HGNC:24903]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane	GO:0003723//RNA binding;GO:0008022//protein C-terminus binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0030154//cell differentiation;GO:0034063//stress granule assembly	--
ENSG00000117525	13.143	13.141	14.06	15.652	16.449	16.178	617	627	494	548	650	557	F3	"coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541]"	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Immune system	ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04610//Complement and coagulation cascades	K03901;K03901	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031233//intrinsic component of external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:1905286//serine-type peptidase complex	GO:0002020//protease binding;GO:0004252//serine-type endopeptidase activity;GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002541//activation of plasma proteins involved in acute inflammatory response;GO:0002543//activation of blood coagulation via clotting cascade;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010628//positive regulation of gene expression;GO:0010641//positive regulation of platelet-derived growth factor receptor signaling pathway;GO:0016485//protein processing;GO:0019221//cytokine-mediated signaling pathway;GO:0030335//positive regulation of cell migration;GO:0032757//positive regulation of interleukin-8 production;GO:0045766//positive regulation of angiogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000117528	43.087	35.272	38.253	30.99	30.889	33.137	3205	2640	2112	1716	1942	1757	ABCD3	ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04146//Peroxisome;ko02010//ABC transporters	K05677;K05677	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0047617//acyl-CoA hydrolase activity;GO:0140359//ABC-type transporter activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006635//fatty acid beta-oxidation;GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0007031//peroxisome organization;GO:0009410//response to xenobiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0015910//long-chain fatty acid import into peroxisome;GO:0042760//very long-chain fatty acid catabolic process;GO:0055085//transmembrane transport;GO:1903512//phytanic acid metabolic process	--
ENSG00000117533	4.208	3.56	3.583	3.302	3.18	5.034	325	247	178	182	196	231	VAMP4	vesicle associated membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:12645]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08513	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031201//SNARE complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0016189//synaptic vesicle to endosome fusion;GO:0016192//vesicle-mediated transport;GO:0035493//SNARE complex assembly;GO:0090161//Golgi ribbon formation;GO:1900242//regulation of synaptic vesicle endocytosis	--
ENSG00000117543	17.277	17.604	17.6	18.264	15.051	18.896	521	536	390	388	395	412	DPH5	diphthamide biosynthesis 5 [Source:HGNC Symbol;Acc:HGNC:24270]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0004164//diphthine synthase activity;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0032259//methylation	--
ENSG00000117560	0	0	0	0	0	0	0	0	0	0	0	0	FASLG	Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Nervous system;Immune disease;Immune disease;Infectious disease: parasitic;Infectious disease: parasitic;Drug resistance: antineoplastic;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04722//Neurotrophin signaling pathway;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko05142//Chagas disease;ko05143//African trypanosomiasis;ko01524//Platinum drug resistance;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389;K04389	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0043202//lysosomal lumen;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0060205//cytoplasmic vesicle lumen;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005123//death receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006925//inflammatory cell apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0016525//negative regulation of angiogenesis;GO:0030644//cellular chloride ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043525//positive regulation of neuron apoptotic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0046666//retinal cell programmed cell death;GO:0048388//endosomal lumen acidification;GO:0070231//T cell apoptotic process;GO:0070266//necroptotic process;GO:0070848//response to growth factor;GO:0071346//cellular response to interferon-gamma;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097527//necroptotic signaling pathway;GO:1903514//release of sequestered calcium ion into cytosol by endoplasmic reticulum;GO:1905782//positive regulation of phosphatidylserine exposure on apoptotic cell surface;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000117569	3.579	3.068	3.99	2.093	2.926	3.116	199	202	149	90	136	131	PTBP2	polypyrimidine tract binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17662]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0043025//neuronal cell body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0021510//spinal cord development;GO:0021549//cerebellum development;GO:0033119//negative regulation of RNA splicing;GO:0043484//regulation of RNA splicing;GO:2000177//regulation of neural precursor cell proliferation	--
ENSG00000117586	0.207	0.151	0.076	0.38	0.2	0.174	15	11	4	20	12	9	TNFSF4	TNF superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11934]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05469	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding	"GO:0001819//positive regulation of cytokine production;GO:0002215//defense response to nematode;GO:0002526//acute inflammatory response;GO:0002639//positive regulation of immunoglobulin production;GO:0002726//positive regulation of T cell cytokine production;GO:0002819//regulation of adaptive immune response;GO:0002830//positive regulation of type 2 immune response;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009615//response to virus;GO:0032689//negative regulation of interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0032722//positive regulation of chemokine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032755//positive regulation of interleukin-6 production;GO:0035709//memory T cell activation;GO:0035712//T-helper 2 cell activation;GO:0035713//response to nitrogen dioxide;GO:0042102//positive regulation of T cell proliferation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043382//positive regulation of memory T cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050871//positive regulation of B cell activation;GO:0071222//cellular response to lipopolysaccharide;GO:0071380//cellular response to prostaglandin E stimulus;GO:1900281//positive regulation of CD4-positive, alpha-beta T cell costimulation;GO:2000572//positive regulation of interleukin-4-dependent isotype switching to IgE isotypes"	--
ENSG00000117592	66.269	66.98	69.14	71.633	71.111	72.102	2323	2360	1790	1860	2106	1839	PRDX6	peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K11188;K11188	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0051920//peroxiredoxin activity	"GO:0006629//lipid metabolic process;GO:0006979//response to oxidative stress;GO:0008152//metabolic process;GO:0016042//lipid catabolic process;GO:0045454//cell redox homeostasis;GO:0046475//glycerophospholipid catabolic process;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0098869//cellular oxidant detoxification"	--
ENSG00000117593	7.934	7.583	7.385	7.507	7.899	8.079	496.87	475.62	371	368	438	400.58	DARS2	"aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01876	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004815//aspartate-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042803//protein homodimerization activity;GO:0050560//aspartate-tRNA(Asn) ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006422//aspartyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0070145//mitochondrial asparaginyl-tRNA aminoacylation	--
ENSG00000117594	0	0	0	0	0.082	0	0	0	0	0	2	0	HSD11B1	hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00140//Steroid hormone biosynthesis	K15680;K15680;K15680;K15680	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005496//steroid binding;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity;GO:0050661//NADP binding;GO:0070524//11-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0102196//cortisol dehydrogenase activity	GO:0006629//lipid metabolic process;GO:0006706//steroid catabolic process;GO:0008202//steroid metabolic process;GO:0030324//lung development	--
ENSG00000117595	3.049	2.772	2.621	1.437	2.355	1.663	215.39	258.08	144.05	99.27	144.38	111.55	IRF6	interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0070062//extracellular exosome	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060644//mammary gland epithelial cell differentiation"	IRF
ENSG00000117597	2.718	2.419	2.368	1.947	2.106	2.167	475	409	302	242	305	269	UTP25	UTP25 small subunit processor component [Source:HGNC Symbol;Acc:HGNC:28440]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0034511//U3 snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0030163//protein catabolic process;GO:0031648//protein destabilization;GO:0040019//positive regulation of embryonic development;GO:0048568//embryonic organ development;GO:1902570//protein localization to nucleolus"	--
ENSG00000117598	0.083	0.065	0.049	0.049	0.108	0.116	7	5	3	3	7	7	PLPPR5	phospholipid phosphatase related 5 [Source:HGNC Symbol;Acc:HGNC:31703]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042577//lipid phosphatase activity	GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0046839//phospholipid dephosphorylation;GO:0051491//positive regulation of filopodium assembly	--
ENSG00000117600	0.03	0.04	0.095	0.027	0.059	0.041	3	4	7	2	5	3	PLPPR4	phospholipid phosphatase related 4 [Source:HGNC Symbol;Acc:HGNC:23496]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0008195//phosphatidate phosphatase activity;GO:0042577//lipid phosphatase activity	"GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007409//axonogenesis;GO:0046839//phospholipid dephosphorylation;GO:0048839//inner ear development;GO:0050804//modulation of chemical synaptic transmission;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0140354//lipid import into cell"	--
ENSG00000117601	0.031	0	0.042	0	0.037	0.043	1	0	1	0	1	1	SERPINC1	serpin family C member 1 [Source:HGNC Symbol;Acc:HGNC:775]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03911	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding	"GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030193//regulation of blood coagulation;GO:2000266//regulation of blood coagulation, intrinsic pathway"	--
ENSG00000117602	1.17	1.365	0.658	0.889	0.81	0.612	121	111	54	52	74	45	RCAN3	RCAN family member 3 [Source:HGNC Symbol;Acc:HGNC:3042]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0019902//phosphatase binding;GO:0031013//troponin I binding	GO:0009653//anatomical structure morphogenesis;GO:0019722//calcium-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000117614	18.928	15.724	14.504	15.259	17.211	19.285	662	576	383	369	507	478	SYF2	SYF2 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:19824]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12868	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071014//post-mRNA release spliceosomal complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006397//mRNA processing;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007369//gastrulation;GO:0008284//positive regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0048568//embryonic organ development"	--
ENSG00000117616	10.573	9.173	9.435	12.737	12.006	13.737	378	349	255	368	388	387	RSRP1	arginine and serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000117620	12.637	9.06	10.14	10.023	10.238	11.041	773.69	566.48	411.06	428.15	535.84	490.75	SLC35A3	solute carrier family 35 member A3 [Source:HGNC Symbol;Acc:HGNC:11023]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005459//UDP-galactose transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005515//protein binding;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity	GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0008643//carbohydrate transport;GO:0072334//UDP-galactose transmembrane transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000117625	10.752	9.799	9.058	8.621	7.651	11.259	796	685	463	460	464	487	RCOR3	REST corepressor 3 [Source:HGNC Symbol;Acc:HGNC:25594]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated"	MYB
ENSG00000117632	71.156	73.465	72.79	65.479	63.745	59.478	1496	1574	1129	1001	1123	912	STMN1	stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510]	Environmental Information Processing;Human Diseases	Signal transduction;Cancer: overview	ko04010//MAPK signaling pathway;ko05206//MicroRNAs in cancer	K04381;K04381	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0043005//neuron projection;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015631//tubulin binding	GO:0000281//mitotic cytokinesis;GO:0007019//microtubule depolymerization;GO:0007052//mitotic spindle organization;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0009615//response to virus;GO:0030154//cell differentiation;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031115//negative regulation of microtubule polymerization;GO:0031175//neuron projection development;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0051272//positive regulation of cellular component movement;GO:0051497//negative regulation of stress fiber assembly;GO:0061436//establishment of skin barrier;GO:0070495//negative regulation of thrombin-activated receptor signaling pathway;GO:1905098//negative regulation of guanyl-nucleotide exchange factor activity	--
ENSG00000117640	31.846	32.164	36.901	31.135	30.072	29.213	1194	1222.97	961	899	981.99	815	MTFR1L	mitochondrial fission regulator 1 like [Source:HGNC Symbol;Acc:HGNC:28836]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0000266//mitochondrial fission;GO:0009060//aerobic respiration	--
ENSG00000117643	121.981	133.443	104.293	66.201	77.809	76.058	9003	9717	5656	3583	4892	4000	MAN1C1	mannosidase alpha class 1C member 1 [Source:HGNC Symbol;Acc:HGNC:19080]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K01230;K01230;K01230;K01230	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular exosome	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006491//N-glycan processing;GO:0008152//metabolic process;GO:0036508//protein alpha-1,2-demannosylation;GO:1904381//Golgi apparatus mannose trimming"	--
ENSG00000117650	0.629	0.544	0.459	0.436	0.54	0.404	22	19	15	13	14	13	NEK2	NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000794//condensed nuclear chromosome;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030496//midbody;GO:0032991//protein-containing complex"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0001824//blastocyst development;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007088//regulation of mitotic nuclear division;GO:0016310//phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0043392//negative regulation of DNA binding;GO:0046602//regulation of mitotic centrosome separation;GO:0046777//protein autophosphorylation;GO:0051225//spindle assembly;GO:0051299//centrosome separation;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051973//positive regulation of telomerase activity;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0090307//mitotic spindle assembly;GO:1903126//negative regulation of centriole-centriole cohesion;GO:1904355//positive regulation of telomere capping	--
ENSG00000117676	7.424	8.054	9.857	8.87	10.32	9.311	487	517	482	435	539	446	RPS6KA1	ribosomal protein S6 kinase A1 [Source:HGNC Symbol;Acc:HGNC:10430]	Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Environmental adaptation;Infectious disease: bacterial;Cancer: overview;Signal transduction;Cell growth and death;Nervous system;Endocrine system;Endocrine and metabolic disease;Nervous system	ko04010//MAPK signaling pathway;ko04714//Thermogenesis;ko05135//Yersinia infection;ko05207//Chemical carcinogenesis - receptor activation;ko04150//mTOR signaling pathway;ko04114//Oocyte meiosis;ko04722//Neurotrophin signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko04720//Long-term potentiation	K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043555//regulation of translation in response to stress;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045597//positive regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0072574//hepatocyte proliferation;GO:2000491//positive regulation of hepatic stellate cell activation"	--
ENSG00000117682	18.241	19.631	19.668	18.278	13.635	14.605	718	807	602	578	659	491	DHDDS	dehydrodolichyl diphosphate synthase subunit [Source:HGNC Symbol;Acc:HGNC:20603]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K11778	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:1904423//dehydrodolichyl diphosphate synthase complex	"GO:0002094//polyprenyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0045547//dehydrodolichyl diphosphate synthase activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0006629//lipid metabolic process;GO:0016094//polyprenol biosynthetic process	--
ENSG00000117691	35.159	34.612	31.213	29.346	26.477	23.075	668	661	438	413	425	319	NENF	neudesin neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:30384]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0032099//negative regulation of appetite;GO:0043410//positive regulation of MAPK cascade;GO:1901215//negative regulation of neuron death	--
ENSG00000117697	11.376	12.249	10.626	7.912	8.974	11.775	422	402	309	211	251	283	NSL1	NSL1 component of MIS12 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24548]	-	-	-	-	"GO:0000444//MIS12/MIND type complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0031617//NMS complex"	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0051301//cell division	--
ENSG00000117707	0.707	0.421	0.313	0.038	0.179	0.117	69	70	26	5	20	15	PROX1	prospero homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9459]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K20211	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0043565//sequence-specific DNA binding;GO:0050692//DNA binding domain binding;GO:0050693//LBD domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001709//cell fate determination;GO:0001822//kidney development;GO:0001889//liver development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001945//lymph vessel development;GO:0001946//lymphangiogenesis;GO:0002088//lens development in camera-type eye;GO:0002089//lens morphogenesis in camera-type eye;GO:0002194//hepatocyte cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007623//circadian rhythm;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010595//positive regulation of endothelial cell migration;GO:0021516//dorsal spinal cord development;GO:0021542//dentate gyrus development;GO:0021707//cerebellar granule cell differentiation;GO:0021915//neural tube development;GO:0030240//skeletal muscle thin filament assembly;GO:0030324//lung development;GO:0030910//olfactory placode formation;GO:0031016//pancreas development;GO:0031667//response to nutrient levels;GO:0042752//regulation of circadian rhythm;GO:0043049//otic placode formation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045071//negative regulation of viral genome replication;GO:0045446//endothelial cell differentiation;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046619//lens placode formation involved in camera-type eye formation;GO:0048511//rhythmic process;GO:0048839//inner ear development;GO:0048845//venous blood vessel morphogenesis;GO:0055005//ventricular cardiac myofibril assembly;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060042//retina morphogenesis in camera-type eye;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0060214//endocardium formation;GO:0060298//positive regulation of sarcomere organization;GO:0060412//ventricular septum morphogenesis;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0060421//positive regulation of heart growth;GO:0060836//lymphatic endothelial cell differentiation;GO:0060838//lymphatic endothelial cell fate commitment;GO:0061114//branching involved in pancreas morphogenesis;GO:0070309//lens fiber cell morphogenesis;GO:0070365//hepatocyte differentiation;GO:0070858//negative regulation of bile acid biosynthetic process;GO:0072574//hepatocyte proliferation;GO:0090425//acinar cell differentiation;GO:0097150//neuronal stem cell population maintenance;GO:1901978//positive regulation of cell cycle checkpoint;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000979//positive regulation of forebrain neuron differentiation"	HPD
ENSG00000117713	20.519	20.908	22.268	20.915	22.628	19.745	3029	3060	2392	2276	2908	2191	ARID1A	AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11653;K11653	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016514//SWI/SNF complex;GO:0035060//brahma complex;GO:0070603//SWI/SNF superfamily-type complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0031491//nucleosome binding	"GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0042766//nucleosome mobilization;GO:0042921//glucocorticoid receptor signaling pathway;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	ARID
ENSG00000117724	0.529	0.261	0.14	0.164	0.15	0.206	113	56	22	26	27	32	CENPF	centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0016363//nuclear matrix;GO:0030496//midbody;GO:0036064//ciliary basal body;GO:0045120//pronucleus;GO:0048471//perinuclear region of cytoplasm;GO:0097539//ciliary transition fiber"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0070840//dynein complex binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000278//mitotic cell cycle;GO:0001822//kidney development;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007517//muscle organ development;GO:0009410//response to xenobiotic stimulus;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0015031//protein transport;GO:0016202//regulation of striated muscle tissue development;GO:0021591//ventricular system development;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0051382//kinetochore assembly;GO:0071897//DNA biosynthetic process"	--
ENSG00000117748	27.974	25.57	28.435	25.469	24.003	26.64	869	812	655	615	651	627	RPA2	replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03430//Mismatch repair	K10739;K10739;K10739;K10739;K10739	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0016604//nuclear body;GO:0016605//PML body;GO:0035861//site of double-strand break"	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0047485//protein N-terminus binding;GO:0098505//G-rich strand telomeric DNA binding	GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006289//nucleotide-excision repair;GO:0006298//mismatch repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0034502//protein localization to chromosome;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000117751	22.565	20.508	22.882	18.799	19.87	22.873	856	842	652	594	658	626	PPP1R8	protein phosphatase 1 regulatory subunit 8 [Source:HGNC Symbol;Acc:HGNC:9296]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008995//ribonuclease E activity;GO:0016787//hydrolase activity;GO:0019888//protein phosphatase regulator activity	GO:0006397//mRNA processing;GO:0006401//RNA catabolic process;GO:0008283//cell population proliferation;GO:0008380//RNA splicing;GO:0035308//negative regulation of protein dephosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000117758	11.934	11.967	12.565	10.106	9.442	10.439	751	757	584	447	502	478	STX12	syntaxin 12 [Source:HGNC Symbol;Acc:HGNC:11430]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K13813	GO:0000139//Golgi membrane;GO:0000407//phagophore assembly site;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0031083//BLOC-1 complex;GO:0031201//SNARE complex;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045335//phagocytic vesicle;GO:0055038//recycling endosome membrane;GO:0098837//postsynaptic recycling endosome	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0033344//cholesterol efflux;GO:0048278//vesicle docking;GO:0050821//protein stabilization	--
ENSG00000117791	3.35	2.037	2.826	3.086	4.277	4.246	139	87	87	98	152	104	MTARC2	mitochondrial amidoxime reducing component 2 [Source:HGNC Symbol;Acc:HGNC:26064]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0008940//nitrate reductase activity;GO:0016491//oxidoreductase activity;GO:0016661//oxidoreductase activity, acting on other nitrogenous compounds as donors;GO:0030151//molybdenum ion binding;GO:0030170//pyridoxal phosphate binding;GO:0043546//molybdopterin cofactor binding;GO:0098809//nitrite reductase activity"	GO:0006809//nitric oxide biosynthetic process;GO:0042126//nitrate metabolic process;GO:0051410//detoxification of nitrogen compound;GO:0070458//cellular detoxification of nitrogen compound	--
ENSG00000117834	0.015	0.015	0	0.062	0.018	0.042	1	1	0	3	1	2	SLC5A9	solute carrier family 5 member 9 [Source:HGNC Symbol;Acc:HGNC:22146]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005362//low-affinity glucose:sodium symporter activity;GO:0005412//glucose:sodium symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008645//hexose transmembrane transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000117859	41.144	36.375	36.099	31.747	33.176	33.955	2171	1972	1335	1229	1421	1282	OSBPL9	oxysterol binding protein like 9 [Source:HGNC Symbol;Acc:HGNC:16386]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0032934//sterol binding	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0015918//sterol transport	--
ENSG00000117862	38.847	39.967	41.029	39.438	40.15	37.951	1140.36	1175.56	887.23	858	995.57	810.09	TXNDC12	thioredoxin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:24626]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K05360;K05360	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity;GO:0019153//protein-disulfide reductase (glutathione) activity	GO:0060548//negative regulation of cell death;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000117868	9.389	8.968	8.752	8.586	8.449	8.942	1155	1109	795	782	878	801	ESYT2	extended synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:22211]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044232//organelle membrane contact site;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0061817//endoplasmic reticulum-plasma membrane tethering	--
ENSG00000117877	2.744	1.694	1.516	1.247	1.557	1.531	71.71	88.35	65.53	54.08	59.14	65.2	POLR1G	RNA polymerase I subunit G [Source:HGNC Symbol;Acc:HGNC:24219]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K25436	GO:0000120//RNA polymerase I transcription regulator complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity	GO:0006360//transcription by RNA polymerase I;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009303//rRNA transcription	--
ENSG00000117899	18.103	18.688	18.836	18.478	16.618	17.619	1534	1591	1166	1152	1180	1085	MESD	mesoderm development LRP chaperone [Source:HGNC Symbol;Acc:HGNC:13520]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0050750//low-density lipoprotein particle receptor binding	GO:0001503//ossification;GO:0006457//protein folding;GO:0006909//phagocytosis;GO:0007498//mesoderm development;GO:0016055//Wnt signaling pathway;GO:0034394//protein localization to cell surface;GO:1904395//positive regulation of skeletal muscle acetylcholine-gated channel clustering	--
ENSG00000117906	54.039	46.718	45.091	40.618	38.842	46.618	2240	2043	1354	1213	1397	1402	RCN2	reticulocalbin 2 [Source:HGNC Symbol;Acc:HGNC:9935]	-	-	-	-	GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000117971	9.599	11.119	11.353	9.906	11.443	8.773	451	534	378	347	452	311	CHRNB4	cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Cancer: overview;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse	K04815;K04815;K04815	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0035579//specific granule membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070821//tertiary granule membrane;GO:0098981//cholinergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001508//action potential;GO:0006811//ion transport;GO:0006939//smooth muscle contraction;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007626//locomotory behavior;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0035095//behavioral response to nicotine;GO:0042391//regulation of membrane potential;GO:0046928//regulation of neurotransmitter secretion;GO:0050877//nervous system process;GO:0051971//positive regulation of transmission of nerve impulse;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0060084//synaptic transmission involved in micturition"	--
ENSG00000117983	0.003	0	0.004	0	0.01	0	1	0	1	0	3	0	MUC5B	"mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516]"	Organismal Systems;Organismal Systems	Digestive system;Immune system	ko04970//Salivary secretion;ko04657//IL-17 signaling pathway	K13908;K13908	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000117984	2048.888	2134.751	2389.01	2674.647	2519.635	2461.332	86867.66	90897.67	74748.7	83852.58	90176.04	75785.85	CTSD	cathepsin D [Source:HGNC Symbol;Acc:HGNC:2529]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing	Infectious disease: bacterial;Cardiovascular disease;Transport and catabolism;Cell growth and death;Transport and catabolism;Endocrine system;Signal transduction	ko05152//Tuberculosis;ko05415//Diabetic cardiomyopathy;ko04140//Autophagy - animal;ko04210//Apoptosis;ko04142//Lysosome;ko04915//Estrogen signaling pathway;ko04071//Sphingolipid signaling pathway	K01379;K01379;K01379;K01379;K01379;K01379;K01379	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0035580//specific granule lumen;GO:0042470//melanosome;GO:0043202//lysosomal lumen;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004190//aspartic-type endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0070001//aspartic-type peptidase activity	GO:0006508//proteolysis;GO:0019538//protein metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042159//lipoprotein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070201//regulation of establishment of protein localization	--
ENSG00000118004	0	0	0.042	0	0	0.125	0	0	1	0	0	2	COLEC11	collectin subfamily member 11 [Source:HGNC Symbol;Acc:HGNC:17213]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K10066	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:1905370//serine-type endopeptidase complex	GO:0003677//DNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0042806//fucose binding;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding;GO:0120153//calcium-dependent carbohydrate binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0019730//antimicrobial humoral response;GO:0032502//developmental process;GO:0045087//innate immune response;GO:0097194//execution phase of apoptosis;GO:1903028//positive regulation of opsonization"	--
ENSG00000118007	11.694	9.099	8.432	7.334	7.523	8.192	1435.3	1108.7	748.7	649.79	752.66	705.69	STAG1	stromal antigen 1 [Source:HGNC Symbol;Acc:HGNC:11354]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06671	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0008278//cohesin complex;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0034991//nuclear meiotic cohesin complex;GO:0097431//mitotic spindle pole"	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0051301//cell division;GO:0090307//mitotic spindle assembly	--
ENSG00000118017	0.027	0	0	0.037	0.032	0.037	1	0	0	1	1	1	A4GNT	"alpha-1,4-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:17968]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing;GO:0050680//negative regulation of epithelial cell proliferation	--
ENSG00000118046	16.783	17.008	22.632	19.445	19.624	19.755	989	1065	931	886	1064	887.87	STK11	serine/threonine kinase 11 [Source:HGNC Symbol;Acc:HGNC:11389]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Cellular community - eukaryotes;Signal transduction;Transport and catabolism;Signal transduction;Signal transduction;Aging;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko04530//Tight junction;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway	K07298;K07298;K07298;K07298;K07298;K07298;K07298;K07298	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0030018//Z disc;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0140535//intracellular protein-containing complex;GO:1902554//serine/threonine protein kinase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030275//LRR domain binding;GO:0030295//protein kinase activator activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0001894//tissue homeostasis;GO:0001944//vasculature development;GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0007409//axonogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0010212//response to ionizing radiation;GO:0010508//positive regulation of autophagy;GO:0014823//response to activity;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030010//establishment of cell polarity;GO:0030111//regulation of Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032147//activation of protein kinase activity;GO:0033762//response to glucagon;GO:0033993//response to lipid;GO:0042593//glucose homeostasis;GO:0043276//anoikis;GO:0043434//response to peptide hormone;GO:0045059//positive thymic T cell selection;GO:0045722//positive regulation of gluconeogenesis;GO:0046777//protein autophosphorylation;GO:0048814//regulation of dendrite morphogenesis;GO:0050772//positive regulation of axonogenesis;GO:0050852//T cell receptor signaling pathway;GO:0051645//Golgi localization;GO:0051726//regulation of cell cycle;GO:0051896//regulation of protein kinase B signaling;GO:0060070//canonical Wnt signaling pathway;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0070314//G1 to G0 transition;GO:0071493//cellular response to UV-B;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097066//response to thyroid hormone;GO:0097484//dendrite extension;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900182//positive regulation of protein localization to nucleus;GO:1901610//positive regulation of vesicle transport along microtubule;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000118058	8.203	6.03	5.609	3.672	5.761	5.072	1524	1256.8	847.46	628	881	712	KMT2A	lysine methyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:7132]	Metabolism;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Endocrine and metabolic disease;Amino acid metabolism	ko01100//Metabolic pathways;ko05202//Transcriptional misregulation in cancer;ko04934//Cushing syndrome;ko00310//Lysine degradation	K09186;K09186;K09186;K09186	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035097//histone methyltransferase complex;GO:0071339//MLL1 complex	GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding;GO:0070577//lysine-acetylated histone binding;GO:0106363//protein-cysteine methyltransferase activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0032259//methylation;GO:0032411//positive regulation of transporter activity;GO:0032922//circadian regulation of gene expression;GO:0035162//embryonic hemopoiesis;GO:0043984//histone H4-K16 acetylation;GO:0044648//histone H3-K4 dimethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051568//histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0065003//protein-containing complex assembly;GO:0071440//regulation of histone H3-K14 acetylation;GO:0080182//histone H3-K4 trimethylation;GO:0097692//histone H3-K4 monomethylation;GO:1905642//negative regulation of DNA methylation;GO:2000615//regulation of histone H3-K9 acetylation"	--
ENSG00000118094	0	0	0	0	0	0	0	0	0	0	0	0	TREH	trehalase [Source:HGNC Symbol;Acc:HGNC:12266]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K01194;K01194	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome	"GO:0004555//alpha,alpha-trehalase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0005991//trehalose metabolic process;GO:0005993//trehalose catabolic process;GO:0008152//metabolic process;GO:0009887//animal organ morphogenesis	--
ENSG00000118096	17.362	19.32	19.024	17.268	15.596	17.542	561	647	435	348	398	421	IFT46	intraflagellar transport 46 [Source:HGNC Symbol;Acc:HGNC:26146]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0120025//plasma membrane bounded cell projection	GO:0003674//molecular_function;GO:0008022//protein C-terminus binding	GO:0008150//biological_process;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0050821//protein stabilization;GO:0060271//cilium assembly	--
ENSG00000118113	0	0.034	0	0	0	0	0	1	0	0	0	0	MMP8	matrix metallopeptidase 8 [Source:HGNC Symbol;Acc:HGNC:7175]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1904724//tertiary granule lumen	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0032693//negative regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035987//endodermal cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0043410//positive regulation of MAPK cascade;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0046330//positive regulation of JNK cascade;GO:0150077//regulation of neuroinflammatory response;GO:0150078//positive regulation of neuroinflammatory response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1903978//regulation of microglial cell activation;GO:1903980//positive regulation of microglial cell activation	--
ENSG00000118137	0	0	0.073	0.145	0.19	0	0	0	1	2	3	0	APOA1	apolipoprotein A1 [Source:HGNC Symbol;Acc:HGNC:600]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cardiovascular disease;Infectious disease: parasitic;Endocrine system;Digestive system;Digestive system;Digestive system	ko05417//Lipid and atherosclerosis;ko05143//African trypanosomiasis;ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism;ko04975//Fat digestion and absorption;ko04977//Vitamin digestion and absorption	K08757;K08757;K08757;K08757;K08757;K08757	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0034774//secretory granule lumen;GO:0042627//chylomicron;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle;GO:1903561//extracellular vesicle	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031210//phosphatidylcholine binding;GO:0034190//apolipoprotein receptor binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045499//chemorepellent activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0070653//high-density lipoprotein particle receptor binding;GO:0071813//lipoprotein particle binding;GO:0120020//cholesterol transfer activity	GO:0001932//regulation of protein phosphorylation;GO:0001935//endothelial cell proliferation;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006869//lipid transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008211//glucocorticoid metabolic process;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010873//positive regulation of cholesterol esterification;GO:0010875//positive regulation of cholesterol efflux;GO:0010898//positive regulation of triglyceride catabolic process;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0018158//protein oxidation;GO:0018206//peptidyl-methionine modification;GO:0019915//lipid storage;GO:0030300//regulation of intestinal cholesterol absorption;GO:0030301//cholesterol transport;GO:0030325//adrenal gland development;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0032691//negative regulation of interleukin-1 beta production;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034380//high-density lipoprotein particle assembly;GO:0034384//high-density lipoprotein particle clearance;GO:0035025//positive regulation of Rho protein signal transduction;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042632//cholesterol homeostasis;GO:0043534//blood vessel endothelial cell migration;GO:0043691//reverse cholesterol transport;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050821//protein stabilization;GO:0050919//negative chemotaxis;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0051180//vitamin transport;GO:0051345//positive regulation of hydrolase activity;GO:0051346//negative regulation of hydrolase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0055091//phospholipid homeostasis;GO:0060354//negative regulation of cell adhesion molecule production;GO:0060761//negative regulation of response to cytokine stimulus;GO:0070328//triglyceride homeostasis;GO:0070508//cholesterol import;GO:0120009//intermembrane lipid transfer;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902995//positive regulation of phospholipid efflux	--
ENSG00000118156	0	0	0	0	0	0	0	0	0	0	0	0	ZNF541	zinc finger protein 541 [Source:HGNC Symbol;Acc:HGNC:25294]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0016575//histone deacetylation;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000118160	0.04	0	0.036	0.036	0	0.055	3	0	2	2	0	3	SLC8A2	solute carrier family 8 member A2 [Source:HGNC Symbol;Acc:HGNC:11069]	Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Sensory system;Signal transduction;Signal transduction;Cardiovascular disease;Circulatory system;Signal transduction;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease;Digestive system;Excretory system	ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04974//Protein digestion and absorption;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0005432//calcium:sodium antiporter activity;GO:0005516//calmodulin binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015491//cation:cation antiporter activity;GO:0046872//metal ion binding;GO:1905060//calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GO:0002931//response to ischemia;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007154//cell communication;GO:0007611//learning or memory;GO:0007612//learning;GO:0007613//memory;GO:0010468//regulation of gene expression;GO:0030001//metal ion transport;GO:0035725//sodium ion transmembrane transport;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0050808//synapse organization;GO:0050890//cognition;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0070050//neuron cellular homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0098703//calcium ion import across plasma membrane;GO:0098815//modulation of excitatory postsynaptic potential;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:0099608//regulation of action potential firing pattern;GO:0106056//regulation of calcineurin-mediated signaling;GO:0150104//transport across blood-brain barrier;GO:1903779//regulation of cardiac conduction;GO:1990034//calcium ion export across plasma membrane	--
ENSG00000118162	5.976	6.04	8.027	6.917	6.239	8.744	198	206	183	157	169	177	KPTN	"kaptin, actin binding protein [Source:HGNC Symbol;Acc:HGNC:6404]"	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031941//filamentous actin;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0098871//postsynaptic actin cytoskeleton;GO:0140007//KICSTOR complex	GO:0003779//actin binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0061462//protein localization to lysosome;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000118181	331.646	349.733	347.848	355.512	266.813	286.433	3326	3526	2577	2645	2263	2090	RPS25	ribosomal protein S25 [Source:HGNC Symbol;Acc:HGNC:10413]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02975;K02975	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0014069//postsynaptic density;GO:0015935//small ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000118193	0.066	0.14	0.067	0.057	0.1	0.068	10	20	7	6	12	7	KIF14	kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0051233//spindle midzone;GO:0090543//Flemming body	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0015631//tubulin binding;GO:0016887//ATP hydrolysis activity;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding	GO:0001558//regulation of cell growth;GO:0007018//microtubule-based movement;GO:0007080//mitotic metaphase plate congression;GO:0008284//positive regulation of cell population proliferation;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0021685//cerebellar granular layer structural organization;GO:0021693//cerebellar Purkinje cell layer structural organization;GO:0021695//cerebellar cortex development;GO:0021766//hippocampus development;GO:0021772//olfactory bulb development;GO:0021846//cell proliferation in forebrain;GO:0021987//cerebral cortex development;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031641//regulation of myelination;GO:0032147//activation of protein kinase activity;GO:0032467//positive regulation of cytokinesis;GO:0032487//regulation of Rap protein signal transduction;GO:0033624//negative regulation of integrin activation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045184//establishment of protein localization;GO:0051301//cell division;GO:1903429//regulation of cell maturation;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000118194	0.97	0.971	0.524	2.435	1.053	1.456	22	23	9	41	21	25	TNNT2	"troponin T2, cardiac type [Source:HGNC Symbol;Acc:HGNC:11949]"	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K12045;K12045;K12045;K12045	GO:0005829//cytosol;GO:0005861//troponin complex;GO:0005865//striated muscle thin filament;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0097512//cardiac myofibril;GO:1990584//cardiac Troponin complex	GO:0000146//microfilament motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0030172//troponin C binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031013//troponin I binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0008016//regulation of heart contraction;GO:0030049//muscle filament sliding;GO:0032780//negative regulation of ATPase activity;GO:0032781//positive regulation of ATPase activity;GO:0032972//regulation of muscle filament sliding speed;GO:0045214//sarcomere organization;GO:0051592//response to calcium ion;GO:0051764//actin crosslink formation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000118197	3.97	4.861	4.106	3.336	3.381	3.405	162	177	124	105	109	91	DDX59	DEAD-box helicase 59 [Source:HGNC Symbol;Acc:HGNC:25360]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	-	--
ENSG00000118200	16.304	10.735	11.023	8.939	9.104	10.808	2181	1436	1041	844	1037	1045	CAMSAP2	calmodulin regulated spectrin associated protein family member 2 [Source:HGNC Symbol;Acc:HGNC:29188]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0036064//ciliary basal body;GO:0036449//microtubule minus-end;GO:0042995//cell projection;GO:1990752//microtubule end	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0030507//spectrin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0031113//regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development;GO:0033043//regulation of organelle organization;GO:0050773//regulation of dendrite development;GO:0061564//axon development;GO:1903358//regulation of Golgi organization	--
ENSG00000118217	24.569	22.036	21.045	16.266	17.017	18.834	2247.98	1974	1471	1102.94	1408.25	1219	ATF6	activating transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:791]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum	K09054;K09054;K09054;K09054;K09054;K09054	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0010508//positive regulation of autophagy;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response;GO:0036503//ERAD pathway;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903893//positive regulation of ATF6-mediated unfolded protein response;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	TF_bZIP
ENSG00000118231	0	0	0	0.101	0	0	0	0	0	1	0	0	CRYGD	crystallin gamma D [Source:HGNC Symbol;Acc:HGNC:2411]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0034614//cellular response to reactive oxygen species;GO:0050896//response to stimulus;GO:0070306//lens fiber cell differentiation	--
ENSG00000118242	3.857	3.381	4.66	3.499	3.195	3.4	211	185	188	143	148	137	MREG	melanoregulin [Source:HGNC Symbol;Acc:HGNC:25478]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031300//intrinsic component of organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0033162//melanosome membrane;GO:0042470//melanosome	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding	GO:0030318//melanocyte differentiation;GO:0032400//melanosome localization;GO:0032402//melanosome transport;GO:0043473//pigmentation;GO:0048066//developmental pigmentation;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0090382//phagosome maturation	--
ENSG00000118245	0	0	0	0	0	0	0	0	0	0	0	0	TNP1	transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951]	-	-	-	-	GO:0000786//nucleosome;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0000012//single strand break repair;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007289//spermatid nucleus differentiation;GO:0007290//spermatid nucleus elongation;GO:0010954//positive regulation of protein processing;GO:0019953//sexual reproduction;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0031507//heterochromatin assembly;GO:0035042//fertilization, exchange of chromosomal proteins;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000118246	10.255	8.98	8.357	7.857	8.155	9.209	723	633	429	386	496	470	FASTKD2	FAST kinase domains 2 [Source:HGNC Symbol;Acc:HGNC:29160]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule;GO:0042645//mitochondrial nucleoid	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0000963//mitochondrial RNA processing;GO:0006396//RNA processing;GO:0006915//apoptotic process;GO:0032543//mitochondrial translation;GO:0042254//ribosome biogenesis;GO:0044528//regulation of mitochondrial mRNA stability;GO:0070131//positive regulation of mitochondrial translation;GO:1902775//mitochondrial large ribosomal subunit assembly	--
ENSG00000118257	19.745	20.631	19.91	10.648	18.804	17.148	2072	2241	1377	941	1276	1209	NRP2	neuropilin 2 [Source:HGNC Symbol;Acc:HGNC:8005]	-	-	-	-	GO:0002116//semaphorin receptor complex;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0017154//semaphorin receptor activity;GO:0019838//growth factor binding;GO:0019955//cytokine binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001755//neural crest cell migration;GO:0001764//neuron migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0003148//outflow tract septum morphogenesis;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007507//heart development;GO:0010595//positive regulation of endothelial cell migration;GO:0021612//facial nerve structural organization;GO:0021649//vestibulocochlear nerve structural organization;GO:0021675//nerve development;GO:0021828//gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0030154//cell differentiation;GO:0036486//ventral trunk neural crest cell migration;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0048846//axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0061549//sympathetic ganglion development;GO:0061551//trigeminal ganglion development;GO:0097374//sensory neuron axon guidance;GO:0097490//sympathetic neuron projection extension;GO:0097491//sympathetic neuron projection guidance;GO:0099175//regulation of postsynapse organization;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1903375//facioacoustic ganglion development;GO:1904835//dorsal root ganglion morphogenesis;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000118260	14.166	13.187	11.778	10.197	9.974	10.298	1303	972	728	589	727	628	CREB1	cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Infectious disease: viral;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Development and regeneration;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Environmental adaptation;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Immune system;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system;Environmental adaptation	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko05152//Tuberculosis;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04612//Antigen processing and presentation;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption;ko04710//Circadian rhythm"	K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870;K05870	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990589//ATF4-CREB1 transcription factor complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0007595//lactation;GO:0007613//memory;GO:0007623//circadian rhythm;GO:0008361//regulation of cell size;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0014074//response to purine-containing compound;GO:0019933//cAMP-mediated signaling;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030879//mammary gland development;GO:0033363//secretory granule organization;GO:0033762//response to glucagon;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0040018//positive regulation of multicellular organism growth;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045600//positive regulation of fat cell differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046887//positive regulation of hormone secretion;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0055025//positive regulation of cardiac muscle tissue development;GO:0060428//lung epithelium development;GO:0060430//lung saccule development;GO:0060509//type I pneumocyte differentiation;GO:0071294//cellular response to zinc ion;GO:0071300//cellular response to retinoic acid;GO:0071363//cellular response to growth factor stimulus;GO:1904322//cellular response to forskolin;GO:1990830//cellular response to leukemia inhibitory factor"	TF_bZIP
ENSG00000118263	2.415	1.728	2.16	1.695	2.24	1.825	246	207	175	136	161	162	KLF7	Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0042593//glucose homeostasis;GO:0045604//regulation of epidermal cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048813//dendrite morphogenesis;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1904178//negative regulation of adipose tissue development"	zf-C2H2
ENSG00000118271	3551.268	3064.443	4608.674	3256.738	3153.417	5210.261	45405	39384	43516	30843	34063	48467	TTR	transthyretin [Source:HGNC Symbol;Acc:HGNC:12405]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K20731	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042562//hormone binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0070324//thyroid hormone binding	GO:0006144//purine nucleobase metabolic process;GO:0007165//signal transduction;GO:0042572//retinol metabolic process;GO:0070327//thyroid hormone transport	--
ENSG00000118276	11.03	8.285	9.63	8.605	7.936	10.183	980	807	673	569	639	718	B4GALT6	"beta-1,4-galactosyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:929]"	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K07553;K07553	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0098791//Golgi apparatus subcompartment	"GO:0008378//galactosyltransferase activity;GO:0008489//UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0001572//lactosylceramide biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0010706//ganglioside biosynthetic process via lactosylceramide;GO:0021955//central nervous system neuron axonogenesis;GO:0022010//central nervous system myelination;GO:0042551//neuron maturation;GO:0070085//glycosylation	--
ENSG00000118292	1.103	0.51	0.676	1.093	1.428	0.53	12	12	8	11	22	10	C1orf54	chromosome 1 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:26258]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000118298	50.318	53.367	60.428	79.921	65.228	70.287	1603	1847	1521	1957	1832	1714	CA14	carbonic anhydrase 14 [Source:HGNC Symbol;Acc:HGNC:1372]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process	--
ENSG00000118307	0.775	0.636	0.471	0.469	0.364	0.18	39	29	15	14	12	6	DNAI7	dynein axonemal intermediate chain 7 [Source:HGNC Symbol;Acc:HGNC:29599]	-	-	-	-	GO:0005737//cytoplasm;GO:0005858//axonemal dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0048487//beta-tubulin binding	-	--
ENSG00000118308	0	0	0	0	0	0.031	0	0	0	0	0	1	IRAG2	"inositol 1,4,5-triphosphate receptor associated 2 [Source:HGNC Symbol;Acc:HGNC:6690]"	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane	GO:0008017//microtubule binding	GO:0002376//immune system process;GO:0006903//vesicle targeting;GO:0006906//vesicle fusion;GO:0006997//nucleus organization;GO:0007338//single fertilization	--
ENSG00000118322	0.199	0.139	0.192	0.192	0.252	0.385	29	22	21	22	30	44	ATP10B	ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:1905103//integral component of lysosomal membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140345//phosphatidylcholine flippase activity;GO:0140351//glycosylceramide flippase activity	GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0034204//lipid translocation;GO:0045332//phospholipid translocation;GO:0097212//lysosomal membrane organization	--
ENSG00000118363	60.383	50.922	56.576	53.122	50.128	61.501	1689	1579	1182	1126	1237	1264	SPCS2	signal peptidase complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28962]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K12947	GO:0005783//endoplasmic reticulum;GO:0005787//signal peptidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0045047//protein targeting to ER	--
ENSG00000118369	3.941	4.373	4.022	3.431	3.71	3.003	226	253	194	157	173	142	USP35	ubiquitin specific peptidase 35 [Source:HGNC Symbol;Acc:HGNC:20061]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000118402	5.152	4.139	4.918	3.607	3.826	6.048	322	260	227	167	202	275	ELOVL4	ELOVL fatty acid elongase 4 [Source:HGNC Symbol;Acc:HGNC:14415]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10249;K10249;K10249;K10249	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0009584//detection of visible light;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process"	--
ENSG00000118407	3.09	2.04	2.705	1.844	1.975	3.213	307	218	196	135	171	226	FILIP1	filamin A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21015]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton	-	-	--
ENSG00000118412	1.73	1.085	0.629	0.646	0.834	0.666	163	107	43	43	89	60	CASP8AP2	caspase 8 associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1510]	-	-	-	-	-	GO:0002020//protease binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding	GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0097190//apoptotic signaling pathway	--
ENSG00000118418	32.056	30.701	29.597	25.844	24.386	30.565	571	550	391	341	368	396	HMGN3	high mobility group nucleosomal binding domain 3 [Source:HGNC Symbol;Acc:HGNC:12312]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0046966//thyroid hormone receptor binding	GO:0006325//chromatin organization;GO:0008150//biological_process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000118420	1.567	1.341	1.56	2.152	1.304	2.15	63	55	46	65	44	64	UBE3D	ubiquitin protein ligase E3D [Source:HGNC Symbol;Acc:HGNC:21381]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination	--
ENSG00000118432	0.111	0.082	0.065	0.062	0.114	0.038	14	9	6	5	11	3	CNR1	cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Environmental adaptation;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04714//Thermogenesis;ko04015//Rap1 signaling pathway;ko04723//Retrograde endocannabinoid signaling	K04277;K04277;K04277;K04277	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0032592//integral component of mitochondrial membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045202//synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0004930//G protein-coupled receptor activity;GO:0004949//cannabinoid receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0099635//voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	"GO:0002866//positive regulation of acute inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007413//axonal fasciculation;GO:0007568//aging;GO:0007584//response to nutrient;GO:0007611//learning or memory;GO:0007613//memory;GO:0010976//positive regulation of neuron projection development;GO:0014063//negative regulation of serotonin secretion;GO:0019216//regulation of lipid metabolic process;GO:0019222//regulation of metabolic process;GO:0019233//sensory perception of pain;GO:0031622//positive regulation of fever generation;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0032496//response to lipopolysaccharide;GO:0033004//negative regulation of mast cell activation;GO:0033602//negative regulation of dopamine secretion;GO:0035094//response to nicotine;GO:0038171//cannabinoid signaling pathway;GO:0042220//response to cocaine;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043271//negative regulation of ion transport;GO:0043278//response to morphine;GO:0045471//response to ethanol;GO:0045759//negative regulation of action potential;GO:0045776//negative regulation of blood pressure;GO:0045777//positive regulation of blood pressure;GO:0050796//regulation of insulin secretion;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051716//cellular response to stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060135//maternal process involved in female pregnancy;GO:0060259//regulation of feeding behavior;GO:0060405//regulation of penile erection;GO:0098921//retrograde trans-synaptic signaling by endocannabinoid;GO:0099533//positive regulation of presynaptic cytosolic calcium concentration;GO:0099553//trans-synaptic signaling by endocannabinoid, modulating synaptic transmission;GO:0099703//induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration"	--
ENSG00000118434	0	0	0	0	0	0	0	0	0	0	0	0	SPACA1	sperm acrosome associated 1 [Source:HGNC Symbol;Acc:HGNC:14967]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002079//inner acrosomal membrane;GO:0002080//acrosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0001675//acrosome assembly;GO:0007283//spermatogenesis	--
ENSG00000118454	9.089	7.107	7.121	5.553	6.045	6.499	783	615	452	355	448	415	ANKRD13C	ankyrin repeat domain 13C [Source:HGNC Symbol;Acc:HGNC:25374]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0006621//protein retention in ER lumen;GO:0010469//regulation of signaling receptor activity;GO:2000209//regulation of anoikis	--
ENSG00000118473	6.858	5.858	7.344	5.272	5.15	7.914	491	389	326	280	311	367	SGIP1	SH3GL interacting endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:25412]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030122//AP-2 adaptor complex;GO:0030136//clathrin-coated vesicle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0017124//SH3 domain binding	GO:0002021//response to dietary excess;GO:0006897//endocytosis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048268//clathrin coat assembly;GO:0072583//clathrin-dependent endocytosis;GO:0097009//energy homeostasis;GO:2000253//positive regulation of feeding behavior	--
ENSG00000118482	7.27	4.613	3.507	2.333	4.661	4.244	1005	642	361	233	487	421	PHF3	PHD finger protein 3 [Source:HGNC Symbol;Acc:HGNC:8921]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated"	--
ENSG00000118491	0	0	0	0	0	0	0	0	0	0	0	0	ZC2HC1B	zinc finger C2HC-type containing 1B [Source:HGNC Symbol;Acc:HGNC:21174]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000118492	0.431	0.018	0.037	0	0.188	0.033	8	2	3	0	2	2	ADGB	androglobin [Source:HGNC Symbol;Acc:HGNC:21212]	-	-	-	-	-	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding	GO:0006508//proteolysis	--
ENSG00000118495	2.832	1.759	2.26	2.336	2.372	1.978	166	105	88	74	109	87	PLAGL1	PLAG1 like zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:9046]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle	zf-C2H2
ENSG00000118496	2.972	2.231	2.43	2.085	2.112	2.482	558	421	337	290	335	339	FBXO30	F-box protein 30 [Source:HGNC Symbol;Acc:HGNC:15600]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000118503	4.879	2.975	2.48	2.238	2.459	3.509	233	233	173	158	201	172	TNFAIP3	TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896]	Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: viral;Immune system;Signal transduction;Cell growth and death;Infectious disease: viral;Signal transduction;Immune system	ko05169//Epstein-Barr virus infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko05162//Measles;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway	K11859;K11859;K11859;K11859;K11859;K11859;K11859	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004842//ubiquitin-protein transferase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0001922//B-1 B cell homeostasis;GO:0002237//response to molecule of bacterial origin;GO:0002634//regulation of germinal center formation;GO:0002677//negative regulation of chronic inflammatory response;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007010//cytoskeleton organization;GO:0008152//metabolic process;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032495//response to muramyl dipeptide;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032703//negative regulation of interleukin-2 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034140//negative regulation of toll-like receptor 3 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0034148//negative regulation of toll-like receptor 5 signaling pathway;GO:0035523//protein K29-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045732//positive regulation of protein catabolic process;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045779//negative regulation of bone resorption;GO:0045824//negative regulation of innate immune response;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050691//regulation of defense response to virus by host;GO:0050728//negative regulation of inflammatory response;GO:0050869//negative regulation of B cell activation;GO:0060548//negative regulation of cell death;GO:0061043//regulation of vascular wound healing;GO:0070301//cellular response to hydrogen peroxide;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0070429//negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070433//negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0070536//protein K63-linked deubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071222//cellular response to lipopolysaccharide;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0072573//tolerance induction to lipopolysaccharide;GO:0072666//establishment of protein localization to vacuole;GO:0090291//negative regulation of osteoclast proliferation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903364//positive regulation of cellular protein catabolic process;GO:1990168//protein K33-linked deubiquitination;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000349//negative regulation of CD40 signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000118507	5.144	4.073	4.399	3.215	3.816	3.46	215	181	123	104	145	114	AKAP7	A-kinase anchoring protein 7 [Source:HGNC Symbol;Acc:HGNC:377]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0032991//protein-containing complex;GO:0098686//hippocampal mossy fiber to CA3 synapse	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0051018//protein kinase A binding	GO:0001508//action potential;GO:0006811//ion transport;GO:0008104//protein localization;GO:0008150//biological_process;GO:0010738//regulation of protein kinase A signaling;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0050804//modulation of chemical synaptic transmission;GO:0060306//regulation of membrane repolarization;GO:0071320//cellular response to cAMP;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1902261//positive regulation of delayed rectifier potassium channel activity	--
ENSG00000118508	24.264	27.293	27.092	30.068	23.522	30.673	536	606	442	492	439	493	RAB32	"RAB32, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9772]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding;GO:0035650//AP-1 adaptor complex binding;GO:0035651//AP-3 adaptor complex binding;GO:0036461//BLOC-2 complex binding	GO:0006886//intracellular protein transport;GO:0007005//mitochondrion organization;GO:0016192//vesicle-mediated transport;GO:0019882//antigen processing and presentation;GO:0032438//melanosome organization;GO:0035646//endosome to melanosome transport;GO:0072657//protein localization to membrane;GO:0090382//phagosome maturation;GO:1903232//melanosome assembly	--
ENSG00000118513	1.199	0.769	0.584	0.139	0.489	0.094	60	54	28	7	18	4	MYB	"MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545]"	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K09420	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0045624//positive regulation of T-helper cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0061515//myeloid cell development;GO:1901533//negative regulation of hematopoietic progenitor cell differentiation"	MYB
ENSG00000118514	0	0	0	0	0.036	0.492	0	0	0	0	1	3	ALDH8A1	aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K23234;K23234	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0001758//retinal dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0047102//aminomuconate-semialdehyde dehydrogenase activity"	GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0097053//L-kynurenine catabolic process	--
ENSG00000118515	79.786	81.253	98.623	93.708	92.813	108.743	4005	4095	3582	3448	3920	3933	SGK1	serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Excretory system	ko04151//PI3K-Akt signaling pathway;ko04150//mTOR signaling pathway;ko04068//FoxO signaling pathway;ko04960//Aldosterone-regulated sodium reabsorption	K13302;K13302;K13302;K13302	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015459//potassium channel regulator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017080//sodium channel regulator activity;GO:0017081//chloride channel regulator activity;GO:0035091//phosphatidylinositol binding;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0006814//sodium ion transport;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007616//long-term memory;GO:0008217//regulation of blood pressure;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030334//regulation of cell migration;GO:0032411//positive regulation of transporter activity;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0048812//neuron projection morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0060453//regulation of gastric acid secretion;GO:0070294//renal sodium ion absorption;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904045//cellular response to aldosterone	--
ENSG00000118518	13.281	13.071	14.477	10.904	12.485	14.976	592	585	472	361	469	484	RNF146	ring finger protein 146 [Source:HGNC Symbol;Acc:HGNC:21336]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0072572//poly-ADP-D-ribose binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000118520	0	0.045	0	0	0	0	0	1	0	0	0	0	ARG1	arginase 1 [Source:HGNC Symbol;Acc:HGNC:663]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: parasitic;Global and overview maps;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko05146//Amoebiasis;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism;ko00220//Arginine biosynthesis	K01476;K01476;K01476;K01476;K01476	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0043005//neuron projection;GO:0043025//neuronal cell body	"GO:0004053//arginase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0000050//urea cycle;GO:0001889//liver development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006525//arginine metabolic process;GO:0006527//arginine catabolic process;GO:0007565//female pregnancy;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009635//response to herbicide;GO:0010042//response to manganese ion;GO:0010043//response to zinc ion;GO:0010269//response to selenium ion;GO:0014075//response to amine;GO:0019547//arginine catabolic process to ornithine;GO:0030324//lung development;GO:0032496//response to lipopolysaccharide;GO:0032964//collagen biosynthetic process;GO:0033189//response to vitamin A;GO:0033197//response to vitamin E;GO:0042130//negative regulation of T cell proliferation;GO:0042832//defense response to protozoan;GO:0043200//response to amino acid;GO:0043434//response to peptide hormone;GO:0045087//innate immune response;GO:0046007//negative regulation of activated T cell proliferation;GO:0046686//response to cadmium ion;GO:0048545//response to steroid hormone;GO:0048678//response to axon injury;GO:0051597//response to methylmercury;GO:0060056//mammary gland involution;GO:0060135//maternal process involved in female pregnancy;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0070965//positive regulation of neutrophil mediated killing of fungus;GO:0071222//cellular response to lipopolysaccharide;GO:0071353//cellular response to interleukin-4;GO:0071377//cellular response to glucagon stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1905541//regulation of L-arginine import across plasma membrane;GO:2000552//negative regulation of T-helper 2 cell cytokine production	--
ENSG00000118523	127.787	131.216	74.156	42.982	59.628	37.211	6197	6396	2656	1544	2443	1313	CCN2	cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04371//Apelin signaling pathway	K06827;K06827	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0031012//extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix	GO:0001968//fibronectin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0008022//protein C-terminus binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001894//tissue homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008544//epidermis development;GO:0009611//response to wounding;GO:0009749//response to glucose;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0014070//response to organic cyclic compound;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0032330//regulation of chondrocyte differentiation;GO:0032355//response to estradiol;GO:0032967//positive regulation of collagen biosynthetic process;GO:0034059//response to anoxia;GO:0035556//intracellular signal transduction;GO:0035988//chondrocyte proliferation;GO:0043200//response to amino acid;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043434//response to peptide hormone;GO:0045597//positive regulation of cell differentiation;GO:0046330//positive regulation of JNK cascade;GO:0050867//positive regulation of cell activation;GO:0051385//response to mineralocorticoid;GO:0051496//positive regulation of stress fiber assembly;GO:0060401//cytosolic calcium ion transport;GO:0060452//positive regulation of cardiac muscle contraction;GO:0060548//negative regulation of cell death;GO:0061448//connective tissue development;GO:0070278//extracellular matrix constituent secretion;GO:0070318//positive regulation of G0 to G1 transition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070542//response to fatty acid;GO:0071897//DNA biosynthetic process;GO:0072593//reactive oxygen species metabolic process	--
ENSG00000118526	0	0	0	0	0	0	0	0	0	0	0	0	TCF21	transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043425//bHLH transcription factor binding;GO:0046983//protein dimerization activity;GO:0050681//androgen receptor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001763//morphogenesis of a branching structure;GO:0001822//kidney development;GO:0001944//vasculature development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007530//sex determination;GO:0007548//sex differentiation;GO:0009887//animal organ morphogenesis;GO:0014707//branchiomeric skeletal muscle development;GO:0030855//epithelial cell differentiation;GO:0032502//developmental process;GO:0032835//glomerulus development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048536//spleen development;GO:0048557//embryonic digestive tract morphogenesis;GO:0048608//reproductive structure development;GO:0048732//gland development;GO:0060008//Sertoli cell differentiation;GO:0060021//roof of mouth development;GO:0060425//lung morphogenesis;GO:0060426//lung vasculature development;GO:0060435//bronchiole development;GO:0060539//diaphragm development;GO:0060541//respiratory system development;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072277//metanephric glomerular capillary formation	bHLH
ENSG00000118557	0	0.028	0.075	0.08	0.033	0.019	0	2	1.09	1.17	2	1	PMFBP1	polyamine modulated factor 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17728]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097224//sperm connecting piece	GO:0003674//molecular_function	GO:0007283//spermatogenesis	--
ENSG00000118564	45.55	42.069	40.291	37.68	38.602	40.96	2919	2740	1984	1820	2124	1972	FBXL5	F-box and leucine rich repeat protein 5 [Source:HGNC Symbol;Acc:HGNC:13602]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0055072//iron ion homeostasis;GO:1903364//positive regulation of cellular protein catabolic process	--
ENSG00000118579	16.351	15.667	15.235	16.655	16.497	17.336	2038.21	1985	1401.8	1363.7	1715.74	1606.93	MED28	mediator complex subunit 28 [Source:HGNC Symbol;Acc:HGNC:24628]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016592//mediator complex;GO:0030864//cortical actin cytoskeleton;GO:0070847//core mediator complex	GO:0003779//actin binding;GO:0005515//protein binding	GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000118596	1.534	0.591	1.007	1.396	0.813	1.199	338	147	133	149	168.99	211	SLC16A7	solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005477//pyruvate secondary active transmembrane transporter activity;GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0050833//pyruvate transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0035873//lactate transmembrane transport;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1901475//pyruvate transmembrane transport	--
ENSG00000118600	13.016	12.023	12.317	11.088	11.917	10.881	485	445	335	307	369	279	RXYLT1	ribitol xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:13530]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K21052;K21052	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0120053//ribitol beta-1,4-xylosyltransferase activity"	GO:0006486//protein glycosylation;GO:0035269//protein O-linked mannosylation	--
ENSG00000118620	2.283	2.339	2.359	2.569	1.102	1.443	147	106	84	89	73.01	82	ZNF430	zinc finger protein 430 [Source:HGNC Symbol;Acc:HGNC:20808]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021762//substantia nigra development"	zf-C2H2
ENSG00000118640	3.124	3.673	4.444	3.481	3.866	2.635	44	52	46	36	46	27	VAMP8	vesicle associated membrane protein 8 [Source:HGNC Symbol;Acc:HGNC:12647]	Cellular Processes;Organismal Systems;Genetic Information Processing	"Transport and catabolism;Immune system;Folding, sorting and degradation"	ko04140//Autophagy - animal;ko04611//Platelet activation;ko04130//SNARE interactions in vesicular transport	K08512;K08512;K08512	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0098594//mucin granule;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019869//chloride channel inhibitor activity;GO:0019905//syntaxin binding	GO:0006906//vesicle fusion;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016240//autophagosome membrane docking;GO:0035493//SNARE complex assembly;GO:0046718//viral entry into host cell;GO:0051607//defense response to virus;GO:0070254//mucus secretion;GO:0097352//autophagosome maturation;GO:1903076//regulation of protein localization to plasma membrane;GO:1903531//negative regulation of secretion by cell;GO:1903595//positive regulation of histamine secretion by mast cell	--
ENSG00000118655	2.75	3.204	3.294	2.7	3.168	2.575	184	209	152	136	190	143	DCLRE1B	DNA cross-link repair 1B [Source:HGNC Symbol;Acc:HGNC:17641]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016604//nuclear body"	GO:0003684//damaged DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0008800//beta-lactamase activity;GO:0016787//hydrolase activity;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding	GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0010833//telomere maintenance via telomere lengthening;GO:0016233//telomere capping;GO:0031627//telomeric loop formation;GO:0031848//protection from non-homologous end joining at telomere;GO:0031860//telomeric 3' overhang formation;GO:0036297//interstrand cross-link repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000118680	138.262	142.146	133.781	128.583	127.635	139.825	3336	3445	2380	2297	2598	2452	MYL12B	myosin light chain 12B [Source:HGNC Symbol;Acc:HGNC:29827]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Development and regeneration;Cellular community - eukaryotes;Immune system;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04360//Axon guidance;ko04530//Tight junction;ko04611//Platelet activation;ko04670//Leukocyte transendothelial migration	K12757;K12757;K12757;K12757;K12757;K12757;K12757;K12757	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005903//brush border;GO:0005938//cell cortex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030016//myofibril;GO:0030018//Z disc;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0032036//myosin heavy chain binding;GO:0046872//metal ion binding	GO:0008360//regulation of cell shape	--
ENSG00000118689	24.385	22.744	21.28	17.422	20.476	21.461	3388.91	3272.88	2362.75	1869.46	2492.7	2143.31	FOXO3	forkhead box O3 [Source:HGNC Symbol;Acc:HGNC:3821]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: bacterial;Cancer: overview;Immune system;Cell growth and death;Endocrine and metabolic disease;Signal transduction;Nervous system;Signal transduction;Aging;Drug resistance: antineoplastic;Endocrine system;Transport and catabolism;Cancer: specific types;Aging;Cancer: specific types	ko04151//PI3K-Akt signaling pathway;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04062//Chemokine signaling pathway;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko04068//FoxO signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05223//Non-small cell lung cancer;ko04213//Longevity regulating pathway - multiple species;ko05213//Endometrial cancer	K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0090571//RNA polymerase II transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019901//protein kinase binding;GO:0031490//chromatin DNA binding;GO:0034246//mitochondrial transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001542//ovulation from ovarian follicle;GO:0001544//initiation of primordial ovarian follicle growth;GO:0001547//antral ovarian follicle growth;GO:0001556//oocyte maturation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006390//mitochondrial transcription;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0010508//positive regulation of autophagy;GO:0014737//positive regulation of muscle atrophy;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030336//negative regulation of cell migration;GO:0031667//response to nutrient levels;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034599//cellular response to oxidative stress;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0042594//response to starvation;GO:0043065//positive regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048854//brain morphogenesis;GO:0070542//response to fatty acid;GO:0071333//cellular response to glucose stimulus;GO:0071386//cellular response to corticosterone stimulus;GO:0071456//cellular response to hypoxia;GO:0071548//response to dexamethasone;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904646//cellular response to amyloid-beta;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990785//response to water-immersion restraint stress;GO:2000177//regulation of neural precursor cell proliferation;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000377//regulation of reactive oxygen species metabolic process"	Fork_head
ENSG00000118690	1.285	1.893	1.33	1.148	1.41	1.18	48	53	32	18	33	36	ARMC2	armadillo repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:23045]	-	-	-	-	-	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation;GO:0044782//cilium organization	--
ENSG00000118702	0	0	0	0	0	0	0	0	0	0	0	0	GHRH	growth hormone releasing hormone [Source:HGNC Symbol;Acc:HGNC:4265]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04935//Growth hormone synthesis, secretion and action"	K05260;K05260	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043195//terminal bouton;GO:0043204//perikaryon	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0016608//growth hormone-releasing hormone activity;GO:0031770//growth hormone-releasing hormone receptor binding;GO:0051428//peptide hormone receptor binding	"GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0021984//adenohypophysis development;GO:0030252//growth hormone secretion;GO:0032094//response to food;GO:0040018//positive regulation of multicellular organism growth;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep;GO:0046887//positive regulation of hormone secretion;GO:0060124//positive regulation of growth hormone secretion"	--
ENSG00000118705	155.042	163.1	143.588	151.39	154.623	157.212	7031	7352	4768	5078	5892	5187	RPN2	ribophorin II [Source:HGNC Symbol;Acc:HGNC:10382]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K12667;K12667;K12667;K12667	GO:0000421//autophagosome membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body	GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0018279//protein N-linked glycosylation via asparagine	--
ENSG00000118707	10.074	10.689	10.629	10.917	11.057	12.546	675.97	673.58	509	482.82	578	536	TGIF2	TGFB induced factor homeobox 2 [Source:HGNC Symbol;Acc:HGNC:15764]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K19553	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010470//regulation of gastrulation;GO:0038092//nodal signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0060041//retina development in camera-type eye"	Homeobox
ENSG00000118729	0.279	0.351	0.352	0.326	0.198	0.46	15	19	14	13	9	18	CASQ2	calsequestrin 2 [Source:HGNC Symbol;Acc:HGNC:1513]	Environmental Information Processing;Organismal Systems	Signal transduction;Circulatory system	ko04020//Calcium signaling pathway;ko04260//Cardiac muscle contraction	K23445;K23445	GO:0005737//cytoplasm;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0034704//calcium channel complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0140314//calcium ion sequestering activity	GO:0002027//regulation of heart rate;GO:0005513//detection of calcium ion;GO:0006874//cellular calcium ion homeostasis;GO:0006941//striated muscle contraction;GO:0010649//regulation of cell communication by electrical coupling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0043267//negative regulation of potassium ion transport;GO:0051208//sequestering of calcium ion;GO:0051258//protein polymerization;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0060048//cardiac muscle contraction;GO:0060306//regulation of membrane repolarization;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0071313//cellular response to caffeine;GO:0086029//Purkinje myocyte to ventricular cardiac muscle cell signaling;GO:1901017//negative regulation of potassium ion transmembrane transporter activity	--
ENSG00000118733	0.091	0.046	0.041	0.062	0.276	0.064	5	3	2	3	14	3	OLFM3	olfactomedin 3 [Source:HGNC Symbol;Acc:HGNC:17990]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0042462//eye photoreceptor cell development	--
ENSG00000118762	18.402	17.128	16.199	11.633	12.243	15.528	1462	1336	931	808	938	988	PKD2	"polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]"	-	-	-	-	GO:0002133//polycystin complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005929//cilium;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0034703//cation channel complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0045180//basal cortex;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0072686//mitotic spindle;GO:0097730//non-motile cilium	GO:0005102//signaling receptor binding;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005267//potassium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0015267//channel activity;GO:0015271//outward rectifier potassium channel activity;GO:0022843//voltage-gated cation channel activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042805//actinin binding;GO:0043398//HLH domain binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0048763//calcium-induced calcium release activity;GO:0051117//ATPase binding;GO:0051219//phosphoprotein binding;GO:0051371//muscle alpha-actinin binding;GO:0051393//alpha-actinin binding	"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0001947//heart looping;GO:0003127//detection of nodal flow;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0021510//spinal cord development;GO:0021915//neural tube development;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0034614//cellular response to reactive oxygen species;GO:0034765//regulation of ion transmembrane transport;GO:0035502//metanephric part of ureteric bud development;GO:0035725//sodium ion transmembrane transport;GO:0035904//aorta development;GO:0042127//regulation of cell population proliferation;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0044782//cilium organization;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050982//detection of mechanical stimulus;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051262//protein tetramerization;GO:0051289//protein homotetramerization;GO:0051290//protein heterotetramerization;GO:0051298//centrosome duplication;GO:0051726//regulation of cell cycle;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060674//placenta blood vessel development;GO:0061333//renal tubule morphogenesis;GO:0061441//renal artery morphogenesis;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071320//cellular response to cAMP;GO:0071464//cellular response to hydrostatic pressure;GO:0071470//cellular response to osmotic stress;GO:0071498//cellular response to fluid shear stress;GO:0071805//potassium ion transmembrane transport;GO:0071910//determination of liver left/right asymmetry;GO:0072075//metanephric mesenchyme development;GO:0072164//mesonephric tubule development;GO:0072177//mesonephric duct development;GO:0072208//metanephric smooth muscle tissue development;GO:0072214//metanephric cortex development;GO:0072218//metanephric ascending thin limb development;GO:0072219//metanephric cortical collecting duct development;GO:0072235//metanephric distal tubule development;GO:0072284//metanephric S-shaped body morphogenesis;GO:0090279//regulation of calcium ion import;GO:0098662//inorganic cation transmembrane transport;GO:0198738//cell-cell signaling by wnt;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000118777	0.056	0	0	0.015	0	0	5	0	0	1	0	0	ABCG2	ATP binding cassette subfamily G member 2 (Junior blood group) [Source:HGNC Symbol;Acc:HGNC:74]	Organismal Systems;Environmental Information Processing;Human Diseases	Digestive system;Membrane transport;Drug resistance: antineoplastic	ko04976//Bile secretion;ko02010//ABC transporters;ko01523//Antifolate resistance	K05681;K05681;K05681	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031966//mitochondrial membrane;GO:0045121//membrane raft;GO:0098591//external side of apical plasma membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008514//organic anion transmembrane transporter activity;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015143//urate transmembrane transporter activity;GO:0015225//biotin transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0032217//riboflavin transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0046983//protein dimerization activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0015878//biotin transport;GO:0032218//riboflavin transport;GO:0042908//xenobiotic transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport;GO:0070633//transepithelial transport;GO:0071702//organic substance transport;GO:0097744//urate salt excretion;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1990748//cellular detoxification;GO:1990962//xenobiotic transport across blood-brain barrier	--
ENSG00000118785	0.818	1.106	0.19	0.353	0.764	0.215	25	29	3	8	21	3	SPP1	secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255]	Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Signal transduction;Immune system;Signaling molecules and interaction;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04371//Apelin signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04512//ECM-receptor interaction;ko04929//GnRH secretion	K06250;K06250;K06250;K06250;K06250;K06250;K06250	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0031982//vesicle;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0050840//extracellular matrix binding	"GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0006710//androgen catabolic process;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007566//embryo implantation;GO:0010033//response to organic substance;GO:0030154//cell differentiation;GO:0031214//biomineral tissue development;GO:0033280//response to vitamin D;GO:0045780//positive regulation of bone resorption;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046697//decidualization;GO:0048545//response to steroid hormone;GO:0048685//negative regulation of collateral sprouting of intact axon in response to injury;GO:0071394//cellular response to testosterone stimulus;GO:2000866//positive regulation of estradiol secretion"	--
ENSG00000118804	1.176	1.098	0.989	0.704	0.822	1.093	54.75	51.39	34	24.26	32.32	37	STBD1	starch binding domain 1 [Source:HGNC Symbol;Acc:HGNC:24854]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0034045//phagophore assembly site membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding;GO:2001069//glycogen binding;GO:2001070//starch binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0006914//autophagy;GO:0046907//intracellular transport;GO:0061723//glycophagy	--
ENSG00000118816	109.303	102.324	100.088	100.902	96.324	108.075	6168	5811	4211	4222	4605	4467	CCNI	cyclin I [Source:HGNC Symbol;Acc:HGNC:1595]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007283//spermatogenesis;GO:0044772//mitotic cell cycle phase transition;GO:0051726//regulation of cell cycle	--
ENSG00000118849	6.442	6.056	4.164	7.467	7.476	8.264	171	186.62	100.88	164.98	205	185	RARRES1	retinoic acid receptor responder 1 [Source:HGNC Symbol;Acc:HGNC:9867]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity	GO:0008285//negative regulation of cell population proliferation;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000118855	26.351	27.68	23.702	28.863	26.212	29.387	1158	1199.38	789.12	923.02	942	932	MFSD1	major facilitator superfamily domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25874]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity;GO:0042803//protein homodimerization activity	GO:0050821//protein stabilization;GO:0055085//transmembrane transport;GO:0061462//protein localization to lysosome	--
ENSG00000118873	8.076	6.63	6.928	5.278	6.071	6.266	1164	902	705	548	705	611	RAB3GAP2	RAB3 GTPase activating non-catalytic protein subunit 2 [Source:HGNC Symbol;Acc:HGNC:17168]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030234//enzyme regulator activity;GO:0031267//small GTPase binding	GO:0006886//intracellular protein transport;GO:0043087//regulation of GTPase activity;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:1903061//positive regulation of protein lipidation;GO:1903373//positive regulation of endoplasmic reticulum tubular network organization;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000118894	6.161	6.121	5.818	5.546	5.918	4.891	268.53	264.53	197.98	191.88	224.92	168.9	EEF2KMT	eukaryotic elongation factor 2 lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:32221]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0006479//protein methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation	--
ENSG00000118898	15.479	14.579	15.58	14.337	15.492	14.034	2007	1900	1492	1377	1697	1324	PPL	periplakin [Source:HGNC Symbol;Acc:HGNC:9273]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0009612//response to mechanical stimulus;GO:0031424//keratinization;GO:0042060//wound healing;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000118900	23.72	22.677	23.599	21.751	24.406	23.989	2736	2674	2086	1987	2437	2067	UBN1	ubinuclein 1 [Source:HGNC Symbol;Acc:HGNC:12506]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005923//bicellular tight junction;GO:0016604//nuclear body;GO:0016605//PML body;GO:0030054//cell junction;GO:0034451//centriolar satellite	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006325//chromatin organization;GO:0006336//DNA replication-independent nucleosome assembly	--
ENSG00000118922	3.77	2.369	2.38	1.947	2.386	2.416	847	535	395	324	453	395	KLF12	Kruppel like factor 12 [Source:HGNC Symbol;Acc:HGNC:6346]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000118939	6.793	6.846	8.246	7.032	5.796	6.17	132	134	119	103	96	88	UCHL3	ubiquitin C-terminal hydrolase L3 [Source:HGNC Symbol;Acc:HGNC:12515]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019784//NEDD8-specific protease activity;GO:0043130//ubiquitin binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0030163//protein catabolic process;GO:0043687//post-translational protein modification	--
ENSG00000118946	1.365	1.329	1.747	0.894	1.371	1.946	235	230	184	114	180	218	PCDH17	protocadherin 17 [Source:HGNC Symbol;Acc:HGNC:14267]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030534//adult behavior;GO:0050805//negative regulation of synaptic transmission;GO:0099560//synaptic membrane adhesion;GO:1904071//presynaptic active zone assembly;GO:2000807//regulation of synaptic vesicle clustering	--
ENSG00000118960	17.845	18.767	21.14	25.217	21.595	19.953	911	949	783	926	895	711	HS1BP3	HCLS1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:24979]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding	GO:0042981//regulation of apoptotic process	--
ENSG00000118961	6.25	8.878	8.183	6.447	8.228	7.971	427	428	325	279	346	347	LDAH	lipid droplet associated hydrolase [Source:HGNC Symbol;Acc:HGNC:26145]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet	GO:0004771//sterol esterase activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019915//lipid storage	--
ENSG00000118965	6.22	5.739	4.817	4.047	4.153	5.047	850	724	500	385	462	438	WDR35	WD repeat domain 35 [Source:HGNC Symbol;Acc:HGNC:29250]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0030991//intraciliary transport particle A;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0035721//intraciliary retrograde transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000118971	14.1	13.528	14.32	13.728	16.644	16.887	1899.49	1832.64	1424.84	1369.49	1893.88	1655.29	CCND2	cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Signal transduction;Cell growth and death;Signal transduction;Infectious disease: viral;Signal transduction;Cell growth and death;Endocrine system;Cell growth and death;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05162//Measles;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04917//Prolactin signaling pathway;ko04115//p53 signaling pathway;ko04340//Hedgehog signaling pathway	K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0097129//cyclin D2-CDK4 complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0001934//positive regulation of protein phosphorylation;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0044772//mitotic cell cycle phase transition;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0051301//cell division;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000118972	0	0	0	0	0	0	0	0	0	0	0	0	FGF23	fibroblast growth factor 23 [Source:HGNC Symbol;Acc:HGNC:3680]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04928//Parathyroid hormone synthesis, secretion and action;ko05218//Melanoma"	K22428;K22428;K22428;K22428;K22428;K22428;K22428;K22428;K22428;K22428;K22428	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen	GO:0005104//fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006796//phosphate-containing compound metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010966//regulation of phosphate transport;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0030643//cellular phosphate ion homeostasis;GO:0032026//response to magnesium ion;GO:0042359//vitamin D metabolic process;GO:0042369//vitamin D catabolic process;GO:0044320//cellular response to leptin stimulus;GO:0045668//negative regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046888//negative regulation of hormone secretion;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071305//cellular response to vitamin D;GO:0071354//cellular response to interleukin-6;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:1904383//response to sodium phosphate"	--
ENSG00000118985	2.41	1.968	1.692	1.519	1.44	1.774	269	239	151	136	147	156	ELL2	elongation factor for RNA polymerase II 2 [Source:HGNC Symbol;Acc:HGNC:17064]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription by RNA polymerase II	--
ENSG00000118997	0.996	1.133	2.481	0.312	0.323	0.424	244	167	116	54	63	61	DNAH7	dynein axonemal heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:18661]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0036156//inner dynein arm;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0036159//inner dynein arm assembly;GO:0060285//cilium-dependent cell motility	--
ENSG00000119004	3.247	3.17	4.093	3.328	4.326	4.187	243	258	199	185	204	212	CYP20A1	cytochrome P450 family 20 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:20576]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	-	--
ENSG00000119013	24.053	23.575	23.422	23.944	19.83	23.24	247	244	177	182	173	174	NDUFB3	NADH:ubiquinone oxidoreductase subunit B3 [Source:HGNC Symbol;Acc:HGNC:7698]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959;K03959	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000119041	7.401	5.502	6.636	5.26	5.533	5.121	609	471	390	310	384	310	GTF3C3	general transcription factor IIIC subunit 3 [Source:HGNC Symbol;Acc:HGNC:4666]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III	--
ENSG00000119042	1.026	0.881	0.908	1.025	0.726	1.031	111	80	73	66	66	76	SATB2	SATB homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21637]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016363//nuclear matrix	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0002076//osteoblast development;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009880//embryonic pattern specification;GO:0010468//regulation of gene expression;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0051216//cartilage development;GO:0060021//roof of mouth development;GO:0071310//cellular response to organic substance	CUT
ENSG00000119048	12.804	13.262	14.361	11.924	10.179	11.387	564	575	449	352	326	353	UBE2B	ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10574	GO:0000785//chromatin;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0033503//HULC complex	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0001701//in utero embryonic development;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0010845//positive regulation of reciprocal meiotic recombination;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0031056//regulation of histone modification;GO:0032446//protein modification by small protein conjugation;GO:0033128//negative regulation of histone phosphorylation;GO:0033522//histone H2A ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0045141//meiotic telomere clustering;GO:0050821//protein stabilization;GO:0051026//chiasma assembly;GO:0051865//protein autoubiquitination;GO:0070076//histone lysine demethylation;GO:0070193//synaptonemal complex organization;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000119121	0.526	0.477	0.689	0.868	0.886	1.31	90	82	87	110	128	163	TRPM6	transient receptor potential cation channel subfamily M member 6 [Source:HGNC Symbol;Acc:HGNC:17995]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K04981	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0009636//response to toxic substance;GO:0016310//phosphorylation;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000119125	0.14	0.098	0.061	0.134	0.094	0.208	15	11	5	11	8	9	GDA	guanine deaminase [Source:HGNC Symbol;Acc:HGNC:4212]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01487;K01487	GO:0005622//intracellular anatomical structure;GO:0005829//cytosol	"GO:0008270//zinc ion binding;GO:0008892//guanine deaminase activity;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0019239//deaminase activity;GO:0046872//metal ion binding"	GO:0000255//allantoin metabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006147//guanine catabolic process;GO:0006161//deoxyguanosine catabolic process;GO:0007399//nervous system development;GO:0046038//GMP catabolic process;GO:0046055//dGMP catabolic process;GO:0046098//guanine metabolic process	--
ENSG00000119138	6.303	5.644	6.275	5.569	5.442	6.905	680	612	500	445	496	542	KLF9	Kruppel like factor 9 [Source:HGNC Symbol;Acc:HGNC:1123]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0010839//negative regulation of keratinocyte proliferation;GO:0048511//rhythmic process;GO:0071387//cellular response to cortisol stimulus;GO:0097067//cellular response to thyroid hormone stimulus	zf-C2H2
ENSG00000119139	14.538	15.755	17.934	15.391	14.475	15.12	1074.33	1170.58	843.62	741.52	836.69	704.12	TJP2	tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Infectious disease: bacterial	ko04530//Tight junction;ko05110//Vibrio cholerae infection	K06098;K06098	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0044291//cell-cell contact zone;GO:0070160//tight junction	GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:1990782//protein tyrosine kinase binding	GO:0034109//homotypic cell-cell adhesion;GO:0035633//maintenance of blood-brain barrier;GO:0045216//cell-cell junction organization;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process;GO:0050892//intestinal absorption;GO:0090557//establishment of endothelial intestinal barrier;GO:0090559//regulation of membrane permeability;GO:0098609//cell-cell adhesion;GO:0150105//protein localization to cell-cell junction;GO:1905605//positive regulation of blood-brain barrier permeability	--
ENSG00000119147	17.671	13.377	19.765	17.892	15.232	15.047	276	210	228	207	201	171	ECRG4	ECRG4 augurin precursor [Source:HGNC Symbol;Acc:HGNC:24642]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding	GO:0007417//central nervous system development;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0042127//regulation of cell population proliferation;GO:0070314//G1 to G0 transition;GO:0090398//cellular senescence	--
ENSG00000119185	33.297	35.659	31.269	29.055	20.936	29.758	1275.93	1349.19	905.88	685.09	655.75	706.96	ITGB1BP1	integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927]	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030027//lamellipodium;GO:0034451//centriolar satellite;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery	GO:0005092//GDP-dissociation inhibitor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding	GO:0001525//angiogenesis;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0006469//negative regulation of protein kinase activity;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007219//Notch signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0010764//negative regulation of fibroblast migration;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0031214//biomineral tissue development;GO:0032091//negative regulation of protein binding;GO:0032148//activation of protein kinase B activity;GO:0033622//integrin activation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0035148//tube formation;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043087//regulation of GTPase activity;GO:0043113//receptor clustering;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045747//positive regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051451//myoblast migration;GO:0051496//positive regulation of stress fiber assembly;GO:0051781//positive regulation of cell division;GO:0051894//positive regulation of focal adhesion assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0072659//protein localization to plasma membrane;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0090314//positive regulation of protein targeting to membrane;GO:0090315//negative regulation of protein targeting to membrane;GO:0097746//blood vessel diameter maintenance;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:2001044//regulation of integrin-mediated signaling pathway	--
ENSG00000119203	16.577	15.585	15.584	12.907	14.81	13.893	764	729	534	443	571	448	CPSF3	cleavage and polyadenylation specific factor 3 [Source:HGNC Symbol;Acc:HGNC:2326]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14403	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004534//5'-3' exoribonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006378//mRNA polyadenylation;GO:0006379//mRNA cleavage;GO:0006397//mRNA processing;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:0031124//mRNA 3'-end processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000119227	1.501	1.41	1.591	1.296	1.653	2.104	57	79	43	51	65	52	PIGZ	phosphatidylinositol glycan anchor biosynthesis class Z [Source:HGNC Symbol;Acc:HGNC:30596]	Metabolism	Glycan biosynthesis and metabolism	ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K08098	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0097502//mannosylation	--
ENSG00000119231	6.247	5.053	4.124	2.689	3.328	4.582	458	405	304	258	342	291	SENP5	SUMO specific peptidase 5 [Source:HGNC Symbol;Acc:HGNC:28407]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0070139//SUMO-specific endopeptidase activity	GO:0006508//proteolysis;GO:0007049//cell cycle;GO:0016926//protein desumoylation;GO:0051301//cell division	--
ENSG00000119242	23.616	24.03	21.643	17.722	21.516	22.4	1043	1025	709	584	759	656	CCDC92	coiled-coil domain containing 92 [Source:HGNC Symbol;Acc:HGNC:29563]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0045087//innate immune response;GO:0050688//regulation of defense response to virus	--
ENSG00000119280	36.209	40.317	34.62	38.578	42.165	33.911	2799	3133	1976	2156	2672	1907	C1orf198	chromosome 1 open reading frame 198 [Source:HGNC Symbol;Acc:HGNC:25900]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	-	-	--
ENSG00000119283	0.185	0.179	0.336	0.736	0.565	0.305	36	35	48	93	81	39	TRIM67	tripartite motif containing 67 [Source:HGNC Symbol;Acc:HGNC:31859]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0010976//positive regulation of neuron projection development;GO:0032880//regulation of protein localization;GO:0046580//negative regulation of Ras protein signal transduction;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000119285	7.932	6.699	6.363	5.757	6.217	7.614	1365.36	1181.44	822.09	748.16	921.65	928.72	HEATR1	HEAT repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25517]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14550	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0030686//90S preribosome;GO:0032040//small-subunit processome;GO:0034455//t-UTP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:2000234//positive regulation of rRNA processing"	--
ENSG00000119314	6.691	5.638	5.635	5.5	5.71	6.542	906	778	575	538	625	648	PTBP3	polypyrimidine tract binding protein 3 [Source:HGNC Symbol;Acc:HGNC:10253]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0033119//negative regulation of RNA splicing;GO:0043249//erythrocyte maturation;GO:0043484//regulation of RNA splicing;GO:0045595//regulation of cell differentiation	--
ENSG00000119318	33.645	31.335	31.404	29.023	28.671	36.684	2871	2686	1978	1764	2067	2277	RAD23B	"RAD23 homolog B, nucleotide excision repair protein [Source:HGNC Symbol;Acc:HGNC:9813]"	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Replication and repair"	ko04141//Protein processing in endoplasmic reticulum;ko03420//Nucleotide excision repair	K10839;K10839	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071942//XPC complex	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0070628//proteasome binding;GO:0140612//DNA damage sensor activity	GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0098761//cellular response to interleukin-7	--
ENSG00000119321	6.607	6.768	6.636	5.206	5.839	6.08	954.86	927.54	644.18	550.35	710.8	643.93	FKBP15	FKBP prolyl isomerase family member 15 [Source:HGNC Symbol;Acc:HGNC:23397]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0003779//actin binding;GO:0005515//protein binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006897//endocytosis	--
ENSG00000119326	104.484	92.511	93.865	83.71	79.803	88.799	5340	4711	3463	3039	3394	3186	CTNNAL1	catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007155//cell adhesion;GO:0007266//Rho protein signal transduction	--
ENSG00000119328	6.011	6.027	5.048	3.835	3.902	6.029	237	232	147	112	130	146	ABITRAM	actin binding transcription modulator [Source:HGNC Symbol;Acc:HGNC:1364]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0030425//dendrite;GO:0030426//growth cone;GO:0032433//filopodium tip;GO:0042995//cell projection	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0030833//regulation of actin filament polymerization;GO:0048813//dendrite morphogenesis;GO:0051489//regulation of filopodium assembly	--
ENSG00000119333	23.749	26.258	27.715	25.727	25.199	26.352	898	998	774	711	805	725	DYNC2I2	dynein 2 intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:28296]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0030175//filopodium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097014//ciliary plasm;GO:0097542//ciliary tip	GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0007018//microtubule-based movement;GO:0035721//intraciliary retrograde transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly	--
ENSG00000119335	161.332	157.505	149.701	127.306	129.882	138.075	6294	6090	4306	3793	4260	4014	SET	SET nuclear proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10760]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0042393//histone binding	"GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly;GO:0035067//negative regulation of histone acetylation;GO:0043086//negative regulation of catalytic activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity"	--
ENSG00000119383	60.828	67.83	73.631	80.305	76.486	79.287	2354.84	2539.98	2032	2300.98	2427.93	2215.95	PTPA	protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308]	Human Diseases;Human Diseases	Cardiovascular disease;Endocrine and metabolic disease	ko05415//Diabetic cardiomyopathy;ko04931//Insulin resistance	K17605;K17605	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0034704//calcium channel complex;GO:0070062//extracellular exosome;GO:1904949//ATPase complex	GO:0000166//nucleotide binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008160//protein tyrosine phosphatase activator activity;GO:0016853//isomerase activity;GO:0019211//phosphatase activator activity;GO:0019888//protein phosphatase regulator activity;GO:0042803//protein homodimerization activity;GO:0051721//protein phosphatase 2A binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006470//protein dephosphorylation;GO:0007052//mitotic spindle organization;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0035308//negative regulation of protein dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000119392	13.424	14.431	14.149	14.27	13.533	13.432	942	998	729	744	796	683	GLE1	GLE1 RNA export mediator [Source:HGNC Symbol;Acc:HGNC:4315]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Neurodegenerative disease;Translation;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K18723;K18723;K18723	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0036064//ciliary basal body;GO:0044614//nuclear pore cytoplasmic filaments	GO:0000822//inositol hexakisphosphate binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0031369//translation initiation factor binding;GO:0042802//identical protein binding	GO:0006406//mRNA export from nucleus;GO:0006446//regulation of translational initiation;GO:0006449//regulation of translational termination;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000119396	29.805	29.433	30.72	26.198	30.418	33.8	2565	2546	1935	1670	1984	1879	RAB14	"RAB14, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16524]"	Environmental Information Processing	Signal transduction	ko04152//AMPK signaling pathway	K07881	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0031489//myosin V binding	GO:0006886//intracellular protein transport;GO:0006895//Golgi to endosome transport;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032456//endocytic recycling;GO:0032880//regulation of protein localization;GO:0042742//defense response to bacterium;GO:0045995//regulation of embryonic development;GO:0046907//intracellular transport;GO:0090382//phagosome maturation;GO:0090387//phagolysosome assembly involved in apoptotic cell clearance	--
ENSG00000119397	1.621	0.703	0.515	0.389	0.582	1.553	92	72	30	22	48	37	CNTRL	centriolin [Source:HGNC Symbol;Acc:HGNC:1858]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0034451//centriolar satellite;GO:0048471//perinuclear region of cytoplasm;GO:0072687//meiotic spindle;GO:0090543//Flemming body;GO:0090619//meiotic spindle pole;GO:0097431//mitotic spindle pole;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding	GO:0001822//kidney development;GO:0003279//cardiac septum development;GO:0003281//ventricular septum development;GO:0007049//cell cycle;GO:0035904//aorta development;GO:0051301//cell division;GO:0051493//regulation of cytoskeleton organization;GO:0060976//coronary vasculature development	--
ENSG00000119401	8.363	7.44	7.454	9.043	7.465	9.158	599	573	423	514	483	511	TRIM32	tripartite motif containing 32 [Source:HGNC Symbol;Acc:HGNC:16380]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10607	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005863//striated muscle myosin thick filament	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017022//myosin binding;GO:0030957//Tat protein binding;GO:0031369//translation initiation factor binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0001894//tissue homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007014//actin ubiquitination;GO:0009411//response to UV;GO:0010508//positive regulation of autophagy;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0032897//negative regulation of viral transcription;GO:0034612//response to tumor necrosis factor;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045444//fat cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045787//positive regulation of cell cycle;GO:0045862//positive regulation of proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046716//muscle cell cellular homeostasis;GO:0048147//negative regulation of fibroblast proliferation;GO:0050769//positive regulation of neurogenesis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0061564//axon development;GO:0070936//protein K48-linked ubiquitination;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1903883//positive regulation of interleukin-17-mediated signaling pathway;GO:1903886//positive regulation of chemokine (C-C motif) ligand 20 production;GO:2000147//positive regulation of cell motility"	--
ENSG00000119402	10.746	9.123	9.569	7.758	9.061	11.098	1666	1530	1207	1026	1274	1211	FBXW2	F-box and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:13608]	-	-	-	-	GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0016567//protein ubiquitination	--
ENSG00000119403	2.805	2.446	2.537	2.972	2.528	2.56	151	140	122	121	154	126	PHF19	PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0019827//stem cell population maintenance;GO:0048863//stem cell differentiation;GO:0061087//positive regulation of histone H3-K27 methylation"	--
ENSG00000119408	72.291	75.207	76.108	74.287	64.324	69.942	3997	4082	3153	3014	3255	2765	NEK6	NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001222//transcription corepressor binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity;GO:0140297//DNA-binding transcription factor binding	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007077//mitotic nuclear membrane disassembly;GO:0007346//regulation of mitotic cell cycle;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046777//protein autophosphorylation;GO:0051225//spindle assembly;GO:0051301//cell division;GO:2000772//regulation of cellular senescence	--
ENSG00000119411	3.148	2.575	3.169	2.209	2.353	1.252	152	125	113	79	96	44	BSPRY	B-box and SPRY domain containing [Source:HGNC Symbol;Acc:HGNC:18232]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0016567//protein ubiquitination;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000119414	15.414	13.599	16.036	13.853	13.877	14.983	1297	1132	942	876	999	929	PPP6C	protein phosphatase 6 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9323]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0002376//immune system process;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0045087//innate immune response;GO:0048208//COPII vesicle coating	--
ENSG00000119421	38.317	35.616	37.591	42.824	37.333	46.152	639	597	463	529	526	560	NDUFA8	NADH:ubiquinone oxidoreductase subunit A8 [Source:HGNC Symbol;Acc:HGNC:7692]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952;K03952	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0044877//protein-containing complex binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000119431	12.951	11.661	11.107	13.514	12.642	11.74	406	368	256	314	335	268	HDHD3	haloacid dehalogenase like hydrolase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28171]	-	-	-	-	GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000119446	6.907	5.85	6.427	6.081	5.825	6.124	713	607	490	465	508	460	RBM18	RNA binding motif protein 18 [Source:HGNC Symbol;Acc:HGNC:28413]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000119457	0.059	0.039	0	0	0	0.105	3	2	0	0	0	3	SLC46A2	solute carrier family 46 member 2 [Source:HGNC Symbol;Acc:HGNC:16055]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0043029//T cell homeostasis;GO:0045580//regulation of T cell differentiation;GO:0048538//thymus development;GO:0055085//transmembrane transport;GO:0070233//negative regulation of T cell apoptotic process;GO:0070430//positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	--
ENSG00000119471	40.344	36.501	34.841	27.959	30.912	29.533	2649	2408	1689	1360	1712	1410	HSDL2	hydroxysteroid dehydrogenase like 2 [Source:HGNC Symbol;Acc:HGNC:18572]	-	-	-	-	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0016020//membrane	GO:0003674//molecular_function;GO:0016491//oxidoreductase activity	GO:0008150//biological_process	--
ENSG00000119487	32.877	32.384	38.215	34.247	33.038	37.473	1872	1856	1392	1375	1472	1345	MAPKAP1	MAPK associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18752]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20410	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031932//TORC2 complex	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0007010//cytoskeleton organization;GO:0016310//phosphorylation;GO:0021762//substantia nigra development;GO:0030307//positive regulation of cell growth;GO:0031669//cellular response to nutrient levels;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038203//TORC2 signaling;GO:0043066//negative regulation of apoptotic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:1900407//regulation of cellular response to oxidative stress	--
ENSG00000119508	0.06	0.251	0.093	0.148	0.253	0.137	7	27	8	12	23	9	NR4A3	nuclear receptor subfamily 4 group A member 3 [Source:HGNC Symbol;Acc:HGNC:7982]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K08559	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0035259//glucocorticoid receptor binding;GO:0035497//cAMP response element binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007369//gastrulation;GO:0009444//pyruvate oxidation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010828//positive regulation of glucose transmembrane transport;GO:0030522//intracellular receptor signaling pathway;GO:0031100//animal organ regeneration;GO:0032765//positive regulation of mast cell cytokine production;GO:0035726//common myeloid progenitor cell proliferation;GO:0038097//positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway;GO:0043303//mast cell degranulation;GO:0043401//steroid hormone mediated signaling pathway;GO:0043434//response to peptide hormone;GO:0044320//cellular response to leptin stimulus;GO:0045333//cellular respiration;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046321//positive regulation of fatty acid oxidation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048660//regulation of smooth muscle cell proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050896//response to stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0071870//cellular response to catecholamine stimulus;GO:0097009//energy homeostasis;GO:1900625//positive regulation of monocyte aggregation;GO:1903208//negative regulation of hydrogen peroxide-induced neuron death;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:2000253//positive regulation of feeding behavior"	NGFIB-like
ENSG00000119509	5.688	5.735	4.792	4.916	4.731	5.093	480	489	310	312	349	317	INVS	inversin [Source:HGNC Symbol;Acc:HGNC:17870]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K19626	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0016020//membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0016055//Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000119514	6.244	4.477	4.086	7.042	6.441	7.473	358	258	173	297	312	307	GALNT12	polypeptide N-acetylgalactosaminyltransferase 12 [Source:HGNC Symbol;Acc:HGNC:19877]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing	--
ENSG00000119522	14.018	13.746	15.576	16.466	15.098	13.103	1400.07	1371.01	1162.38	1240.17	1273.37	947.06	DENND1A	DENN domain containing 1A [Source:HGNC Symbol;Acc:HGNC:29324]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0030425//dendrite;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098793//presynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0008289//lipid binding;GO:0017124//SH3 domain binding;GO:0031267//small GTPase binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0032483//regulation of Rab protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0048488//synaptic vesicle endocytosis;GO:0050790//regulation of catalytic activity	--
ENSG00000119523	23.825	22.779	25.209	26.16	21.29	26.803	1028	1022	802	832	789	826	ALG2	"ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23159]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03843;K03843;K03843	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0004378//GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding;GO:0048306//calcium-dependent protein binding;GO:0102704//GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0033577//protein glycosylation in endoplasmic reticulum;GO:0051592//response to calcium ion;GO:0097502//mannosylation	--
ENSG00000119535	0	0	0	0	0	0	0	0	0	0	0	0	CSF3R	colony stimulating factor 3 receptor [Source:HGNC Symbol;Acc:HGNC:2439]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05061;K05061;K05061;K05061;K05061	GO:0005576//extracellular region;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0038023//signaling receptor activity;GO:0051916//granulocyte colony-stimulating factor binding	GO:0006952//defense response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0045637//regulation of myeloid cell differentiation	--
ENSG00000119537	18.877	22.634	17.936	18.954	20.807	21.775	1267	1237	853	878	1089	1021	KDSR	3-ketodihydrosphingosine reductase [Source:HGNC Symbol;Acc:HGNC:4021]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K04708;K04708	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0047560//3-dehydrosphinganine reductase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006666//3-keto-sphinganine metabolic process;GO:0030148//sphingolipid biosynthetic process	--
ENSG00000119541	11.145	8.705	9.827	6.934	8.446	11.414	659	594	395	343	404	367	VPS4B	vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12196;K12196	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome;GO:0090543//Flemming body;GO:1904949//ATPase complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding	GO:0001778//plasma membrane repair;GO:0006813//potassium ion transport;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007032//endosome organization;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0010824//regulation of centrosome duplication;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0016236//macroautophagy;GO:0030301//cholesterol transport;GO:0031468//nuclear membrane reassembly;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0033993//response to lipid;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046761//viral budding from plasma membrane;GO:0051261//protein depolymerization;GO:0051301//cell division;GO:0060548//negative regulation of cell death;GO:0061738//late endosomal microautophagy;GO:0061764//late endosome to lysosome transport via multivesicular body sorting pathway;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0090611//ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1903542//negative regulation of exosomal secretion;GO:1903543//positive regulation of exosomal secretion;GO:1903724//positive regulation of centriole elongation;GO:1904903//ESCRT III complex disassembly	--
ENSG00000119547	0.05	0.041	0.02	0.02	0.042	0.008	17	14	5	5	12	2	ONECUT2	one cut homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8139]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001889//liver development;GO:0001952//regulation of cell-matrix adhesion;GO:0002064//epithelial cell development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048935//peripheral nervous system neuron development;GO:0060271//cilium assembly	CUT
ENSG00000119559	13.678	15.548	18.315	18.089	16.229	20.223	463	555.06	443	439	456	511	C19orf25	chromosome 19 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:26711]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000119574	6.673	7.518	7.066	8.13	7.487	7.376	296	320	231	252	275	237	ZBTB45	zinc finger and BTB domain containing 45 [Source:HGNC Symbol;Acc:HGNC:23715]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development	ZBTB
ENSG00000119596	15.897	17.749	16.013	13.665	16.636	14.133	1926	2038	1431	1185	1582	1197	YLPM1	YLP motif containing 1 [Source:HGNC Symbol;Acc:HGNC:17798]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0008150//biological_process;GO:0032204//regulation of telomere maintenance	--
ENSG00000119599	3.059	3.947	3.534	3.571	4.445	2.96	151	194	126	132	180	105	DCAF4	DDB1 and CUL4 associated factor 4 [Source:HGNC Symbol;Acc:HGNC:20229]	-	-	-	-	GO:0005654//nucleoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000119608	0.037	0.012	0	0.066	0.102	0.051	3	1	0	4	7	3	PROX2	prospero homeobox 2 [Source:HGNC Symbol;Acc:HGNC:26715]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HPD
ENSG00000119614	0.575	0.461	0.649	0.237	0.189	0.088	36	29	30	11	10	4	VSX2	visual system homeobox 2 [Source:HGNC Symbol;Acc:HGNC:1975]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0050896//response to stimulus"	Homeobox
ENSG00000119616	20.856	20.346	23.74	17.586	17.729	21.333	484	473	389	294	335	351	FCF1	FCF1 rRNA-processing protein [Source:HGNC Symbol;Acc:HGNC:20220]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14566	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0010467//gene expression;GO:0042254//ribosome biogenesis	--
ENSG00000119630	5.209	4.575	7.099	4.419	5.208	6.946	186	163	187	116	156	180	PGF	placental growth factor [Source:HGNC Symbol;Acc:HGNC:8893]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion	K16859;K16859;K16859;K16859;K16859;K16859	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane	GO:0005172//vascular endothelial growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0048018//receptor ligand activity	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0030154//cell differentiation;GO:0031100//animal organ regeneration;GO:0032870//cellular response to hormone stimulus;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051781//positive regulation of cell division;GO:0060754//positive regulation of mast cell chemotaxis	--
ENSG00000119632	17.638	19.675	24.027	18.039	13.286	15.427	165	185	166	125	105	105	IFI27L2	interferon alpha inducible protein 27 like 2 [Source:HGNC Symbol;Acc:HGNC:19753]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway	--
ENSG00000119636	2.519	2.626	2.782	2.424	1.822	1.13	115.14	96	88	61	63	53.08	BBOF1	basal body orientation factor 1 [Source:HGNC Symbol;Acc:HGNC:19855]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	-	GO:0044458//motile cilium assembly	--
ENSG00000119638	25.804	27.996	27.502	22.838	26.706	26.299	2172.22	2328.1	1636.87	1516.02	1882.33	1643	NEK9	NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC:18591]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0051301//cell division	--
ENSG00000119640	0.864	1.151	0.85	1.07	1.875	0.759	11	15	8	11	20	7	ACYP1	acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K01512;K01512	-	GO:0003998//acylphosphatase activity;GO:0016787//hydrolase activity	GO:0006796//phosphate-containing compound metabolic process	--
ENSG00000119650	13.914	14.025	11.453	10.151	9.614	11.68	239	241	147	129	139	146	IFT43	intraflagellar transport 43 [Source:HGNC Symbol;Acc:HGNC:29669]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0030991//intraciliary transport particle A;GO:0034451//centriolar satellite;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0035721//intraciliary retrograde transport;GO:0060271//cilium assembly	--
ENSG00000119655	824.422	853.871	829.559	788.711	683.041	720.204	10368	10913	7704	7414	7365	6582	NPC2	NPC intracellular cholesterol transporter 2 [Source:HGNC Symbol;Acc:HGNC:14537]	Cellular Processes;Organismal Systems	Transport and catabolism;Digestive system	ko04142//Lysosome;ko04979//Cholesterol metabolism	K13443;K13443	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0032934//sterol binding;GO:0120020//cholesterol transfer activity	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009615//response to virus;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0019747//regulation of isoprenoid metabolic process;GO:0030301//cholesterol transport;GO:0032366//intracellular sterol transport;GO:0032367//intracellular cholesterol transport;GO:0033344//cholesterol efflux;GO:0042632//cholesterol homeostasis;GO:0046836//glycolipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000119661	6.918	8.532	6.466	3.749	4.925	6.482	585	570	395	282	353	321	DNAL1	dynein axonemal light chain 1 [Source:HGNC Symbol;Acc:HGNC:23247]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10411;K10411;K10411	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0036157//outer dynein arm;GO:0042995//cell projection	GO:0005515//protein binding;GO:0043014//alpha-tubulin binding;GO:0045504//dynein heavy chain binding	GO:0036158//outer dynein arm assembly	--
ENSG00000119669	23.134	23.948	26.528	25.966	25.93	27.977	1999	2080	1693	1662	1893	1759	IRF2BPL	interferon regulatory factor 2 binding protein like [Source:HGNC Symbol;Acc:HGNC:14282]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0016567//protein ubiquitination;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046543//development of secondary female sexual characteristics	--
ENSG00000119673	10.239	10.386	11.659	14.343	12.535	13.705	333.49	344.48	278.42	346.35	345.09	322.99	ACOT2	acyl-CoA thioesterase 2 [Source:HGNC Symbol;Acc:HGNC:18431]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04913//Ovarian steroidogenesis;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K01068;K01068;K01068;K01068	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000119681	33.461	39.506	26.055	14.136	16.759	13.24	5788	6751	3198	1711	2448	1618	LTBP2	latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0019838//growth factor binding;GO:0050436//microfibril binding	GO:0006605//protein targeting;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009306//protein secretion;GO:0097435//supramolecular fiber organization	--
ENSG00000119682	17.162	18.17	20.387	16.814	18.254	19.09	1783	1920	1521	1361	1631	1480	AREL1	apoptosis resistant E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20363]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0050727//regulation of inflammatory response;GO:0070979//protein K11-linked ubiquitination;GO:1990390//protein K33-linked ubiquitination	--
ENSG00000119684	4.38	4.026	3.549	2.566	2.125	3.243	365	304	207	167	172	187	MLH3	mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128]	Genetic Information Processing	Replication and repair	ko03430//Mismatch repair	K08739	GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005712//chiasma;GO:0032300//mismatch repair complex	GO:0003682//chromatin binding;GO:0003696//satellite DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019237//centromeric DNA binding;GO:0030983//mismatched DNA binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0007144//female meiosis I;GO:0008104//protein localization	--
ENSG00000119685	7.197	7.665	7.861	4.943	5.991	6.539	631	645	484	319	428	411	TTLL5	tubulin tyrosine ligase like 5 [Source:HGNC Symbol;Acc:HGNC:19963]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation;GO:0060041//retina development in camera-type eye	--
ENSG00000119686	23.477	22.918	25.42	23.52	28.646	27.23	1542	1557	1355	1299	1625	1402	FLVCR2	FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015232//heme transmembrane transporter activity;GO:0020037//heme binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport;GO:0097037//heme export	--
ENSG00000119688	18.105	18.068	20.331	19.826	18.271	17.34	617	657	468	464	563	476	ABCD4	ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04146//Peroxisome;ko02010//ABC transporters	K05678;K05678	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex	GO:0000166//nucleotide binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015420//ABC-type vitamin B12 transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006635//fatty acid beta-oxidation;GO:0007031//peroxisome organization;GO:0009235//cobalamin metabolic process;GO:0015889//cobalamin transport;GO:0015910//long-chain fatty acid import into peroxisome;GO:0042760//very long-chain fatty acid catabolic process;GO:0055085//transmembrane transport;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000119689	29.762	31.191	33.279	30.523	31.239	29.029	1568	1720	1294	1276	1475	1201	DLST	dihydrolipoamide S-succinyltransferase [Source:HGNC Symbol;Acc:HGNC:2911]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00310//Lysine degradation;ko00380//Tryptophan metabolism;ko00020//Citrate cycle (TCA cycle)	K00658;K00658;K00658;K00658;K00658	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0045252//oxoglutarate dehydrogenase complex;GO:1990204//oxidoreductase complex	GO:0004149//dihydrolipoyllysine-residue succinyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006082//organic acid metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006099//tricarboxylic acid cycle;GO:0006103//2-oxoglutarate metabolic process;GO:0006104//succinyl-CoA metabolic process;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0106077//histone succinylation	--
ENSG00000119698	4.65	3.712	4.031	2.717	3.151	3.436	372	286	216	161	213	200	PPP4R4	protein phosphatase 4 regulatory subunit 4 [Source:HGNC Symbol;Acc:HGNC:23788]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008287//protein serine/threonine phosphatase complex	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0001835//blastocyst hatching;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0080163//regulation of protein serine/threonine phosphatase activity	--
ENSG00000119699	3.773	3.789	3.272	4.854	3.602	2.762	268	263	172	177	171	143	TGFB3	transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: parasitic;Cancer: specific types;Cardiovascular disease;Infectious disease: viral;Immune disease;Cell growth and death;Signal transduction;Cancer: specific types;Infectious disease: parasitic;Signal transduction;Cell growth and death;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cardiovascular disease;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune disease;Infectious disease: parasitic	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05146//Amoebiasis;ko05225//Hepatocellular carcinoma;ko05414//Dilated cardiomyopathy;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko05140//Leishmaniasis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05410//Hypertrophic cardiomyopathy;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05321//Inflammatory bowel disease;ko05144//Malaria	K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377;K13377	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0030315//T-tubule;GO:0031093//platelet alpha granule lumen;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix	GO:0005114//type II transforming growth factor beta receptor binding;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0034714//type III transforming growth factor beta receptor binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0050431//transforming growth factor beta binding	"GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007435//salivary gland morphogenesis;GO:0007565//female pregnancy;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010936//negative regulation of macrophage cytokine production;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030879//mammary gland development;GO:0032570//response to progesterone;GO:0032967//positive regulation of collagen biosynthetic process;GO:0034616//response to laminar fluid shear stress;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042476//odontogenesis;GO:0042704//uterine wall breakdown;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0043627//response to estrogen;GO:0043932//ossification involved in bone remodeling;GO:0045216//cell-cell junction organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048565//digestive tract development;GO:0048702//embryonic neurocranium morphogenesis;GO:0048839//inner ear development;GO:0050714//positive regulation of protein secretion;GO:0051491//positive regulation of filopodium assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051781//positive regulation of cell division;GO:0060325//face morphogenesis;GO:0060364//frontal suture morphogenesis;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0062009//secondary palate development;GO:0070483//detection of hypoxia;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1905075//positive regulation of tight junction disassembly"	--
ENSG00000119703	3.904	3.349	3.097	2.4	2.674	2.492	152.78	125.9	88.13	73.98	95.68	68	ZC2HC1C	zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000119705	16.283	8.651	11.267	14.552	9.739	12.588	130	69	66	87	66	73	SLIRP	SRA stem-loop interacting RNA binding protein [Source:HGNC Symbol;Acc:HGNC:20495]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0036126//sperm flagellum;GO:0048471//perinuclear region of cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000961//negative regulation of mitochondrial RNA catabolic process;GO:0007286//spermatid development;GO:0007338//single fertilization;GO:0030317//flagellated sperm motility;GO:0070584//mitochondrion morphogenesis	--
ENSG00000119707	7.405	6.397	5.208	3.406	6.123	5.938	566	515	306	199	391	343	RBM25	RNA binding motif protein 25 [Source:HGNC Symbol;Acc:HGNC:23244]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12822	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0042981//regulation of apoptotic process"	--
ENSG00000119711	10.738	12.395	12.869	13.401	17.151	12.651	1018.48	1095	818	893	1076	835.92	ALDH6A1	aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00562//Inositol phosphate metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism"	K00140;K00140;K00140;K00140;K00140;K00140	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000062//fatty-acyl-CoA binding;GO:0003723//RNA binding;GO:0004491//methylmalonate-semialdehyde dehydrogenase (acylating) activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0018478//malonate-semialdehyde dehydrogenase (acetylating) activity;GO:0102662//malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity"	GO:0006210//thymine catabolic process;GO:0006573//valine metabolic process;GO:0006574//valine catabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0019859//thymine metabolic process;GO:0050873//brown fat cell differentiation	--
ENSG00000119714	1.04	1.371	1.055	0.899	0.463	0.724	59	76	48	42	24	25	GPR68	G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045656//negative regulation of monocyte differentiation;GO:0071467//cellular response to pH;GO:2001206//positive regulation of osteoclast development	--
ENSG00000119715	0	0.094	0	0	0.023	0	0	3	0	0	2	0	ESRRB	estrogen related receptor beta [Source:HGNC Symbol;Acc:HGNC:3473]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K08553	GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032039//integrator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008283//cell population proliferation;GO:0017145//stem cell division;GO:0019827//stem cell population maintenance;GO:0030522//intracellular receptor signaling pathway;GO:0043401//steroid hormone mediated signaling pathway;GO:0043697//cell dedifferentiation;GO:0045494//photoreceptor cell maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:0071931//positive regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0090282//positive regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:1902459//positive regulation of stem cell population maintenance;GO:2000035//regulation of stem cell division;GO:2000737//negative regulation of stem cell differentiation"	ESR-like
ENSG00000119718	11.741	14.333	16.061	12.95	13.703	12.933	688	817	585	527	541	494	EIF2B2	eukaryotic translation initiation factor 2B subunit beta [Source:HGNC Symbol;Acc:HGNC:3258]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K03754	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex	GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding	GO:0001541//ovarian follicle development;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0007417//central nervous system development;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0014003//oligodendrocyte development;GO:0042552//myelination;GO:0043434//response to peptide hormone;GO:0044237//cellular metabolic process;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000119720	3.633	4.098	4.222	3.48	3.302	4.066	417.13	443.71	346.35	285.7	310.83	333.42	NRDE2	"NRDE-2, necessary for RNA interference, domain containing [Source:HGNC Symbol;Acc:HGNC:20186]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0016246//RNA interference;GO:0031048//heterochromatin assembly by small RNA;GO:0046833//positive regulation of RNA export from nucleus;GO:0051301//cell division;GO:1902369//negative regulation of RNA catabolic process	--
ENSG00000119723	4.851	5.242	6.933	6.797	8.195	5.686	172.49	172.96	134.33	150.87	165	147.46	COQ6	"coenzyme Q6, monooxygenase [Source:HGNC Symbol;Acc:HGNC:20233]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K06126;K06126	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0042995//cell projection;GO:0110142//ubiquinone biosynthesis complex	"GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0008681//2-octaprenyl-6-methoxyphenol hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding;GO:0106364//4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity"	GO:0006744//ubiquinone biosynthetic process	--
ENSG00000119725	21.909	22.17	22.104	16.962	18.508	18.6	785.23	810.59	618.31	505.36	595.99	561.78	ZNF410	zinc finger protein 410 [Source:HGNC Symbol;Acc:HGNC:20144]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010629//negative regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000119729	69.325	64.519	66.415	54.087	51.189	74.437	4813.76	3899.23	3027.92	2384.14	2953.64	3167.1	RHOQ	ras homolog family member Q [Source:HGNC Symbol;Acc:HGNC:17736]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K07194	GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0005525//GTP binding;GO:0032427//GBD domain binding	GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030031//cell projection assembly;GO:0030866//cortical actin cytoskeleton organization;GO:0032869//cellular response to insulin stimulus;GO:0032956//regulation of actin cytoskeleton organization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046039//GTP metabolic process;GO:0046326//positive regulation of glucose import;GO:0051491//positive regulation of filopodium assembly;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000119737	0.368	0.275	0.094	0.435	0.245	0.285	16	12	3	14	9	9	GPR75	G protein-coupled receptor 75 [Source:HGNC Symbol;Acc:HGNC:4526]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0016493//C-C chemokine receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:1901214//regulation of neuron death	--
ENSG00000119760	15.602	15.805	16.707	13.002	15.754	17.065	1038.95	985.04	794.08	613.36	859.21	799.78	SUPT7L	"SPT7 like, STAGA complex subunit gamma [Source:HGNC Symbol;Acc:HGNC:30632]"	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0006282//regulation of DNA repair;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus"	--
ENSG00000119771	9.41	9.551	7.917	5.919	6.721	6.961	1016	1012	630	470	613	538	KLHL29	kelch like family member 29 [Source:HGNC Symbol;Acc:HGNC:29404]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000119772	12.636	13.757	15.851	12.04	12.937	14.911	1631	1684	1466	1018	1415	1379	DNMT3A	DNA methyltransferase 3 alpha [Source:HGNC Symbol;Acc:HGNC:2978]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko00270//Cysteine and methionine metabolism	K17398;K17398;K17398	"GO:0000775//chromosome, centromeric region;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:1902494//catalytic complex"	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106363//protein-cysteine methyltransferase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006479//protein methylation;GO:0007283//spermatogenesis;GO:0007568//aging;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010212//response to ionizing radiation;GO:0010288//response to lead ion;GO:0010468//regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0030182//neuron differentiation;GO:0031667//response to nutrient levels;GO:0032259//methylation;GO:0032355//response to estradiol;GO:0032776//DNA methylation on cytosine;GO:0033189//response to vitamin A;GO:0042220//response to cocaine;GO:0043045//DNA methylation involved in embryo development;GO:0043046//DNA methylation involved in gamete generation;GO:0045471//response to ethanol;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071230//cellular response to amino acid stimulus;GO:0071361//cellular response to ethanol;GO:0071456//cellular response to hypoxia;GO:0090116//C-5 methylation of cytosine;GO:0097284//hepatocyte apoptotic process;GO:1903926//cellular response to bisphenol A"	--
ENSG00000119777	31.899	35.329	36.865	36.933	36.175	30.504	1968	2150	1596	1575	1771	1352	TMEM214	transmembrane protein 214 [Source:HGNC Symbol;Acc:HGNC:25983]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006915//apoptotic process	--
ENSG00000119778	1.981	1.523	1.465	1.223	1.38	1.542	317	243	182	135	178	162	ATAD2B	ATPase family AAA domain containing 2B [Source:HGNC Symbol;Acc:HGNC:29230]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0070577//lysine-acetylated histone binding	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000119782	5.753	5.229	5.358	5.157	3.894	6.022	113	103.81	77	78	66	88	FKBP1B	FKBP prolyl isomerase 1B [Source:HGNC Symbol;Acc:HGNC:3712]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0033017//sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005102//signaling receptor binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0019855//calcium channel inhibitor activity;GO:0030551//cyclic nucleotide binding;GO:0044325//transmembrane transporter binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0002027//regulation of heart rate;GO:0006458//'de novo' protein folding;GO:0006939//smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0009749//response to glucose;GO:0010033//response to organic substance;GO:0010459//negative regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0019227//neuronal action potential propagation;GO:0022417//protein maturation by protein folding;GO:0030073//insulin secretion;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0033197//response to vitamin E;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042026//protein refolding;GO:0042098//T cell proliferation;GO:0042542//response to hydrogen peroxide;GO:0048680//positive regulation of axon regeneration;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0051284//positive regulation of sequestering of calcium ion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051775//response to redox state;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0061077//chaperone-mediated protein folding;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0086064//cell communication by electrical coupling involved in cardiac conduction	--
ENSG00000119787	7.809	7.352	8.129	6.917	7.994	9.369	465	440	356	313	402	369	ATL2	atlastin GTPase 2 [Source:HGNC Symbol;Acc:HGNC:24047]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098826//endoplasmic reticulum tubular network membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0051260//protein homooligomerization;GO:1990809//endoplasmic reticulum tubular network membrane organization	--
ENSG00000119801	55.187	51.717	51.642	48.665	47.321	59.879	2477	2348	1720	1621	1787	1966	YPEL5	yippee like 5 [Source:HGNC Symbol;Acc:HGNC:18329]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000922//spindle pole;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0097431//mitotic spindle pole;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008283//cell population proliferation	--
ENSG00000119812	16.834	15.277	16.42	14.763	15.585	16.452	917	840	678	588	719	670	FAM98A	family with sequence similarity 98 member A [Source:HGNC Symbol;Acc:HGNC:24520]	-	-	-	-	GO:0072669//tRNA-splicing ligase complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008276//protein methyltransferase activity	GO:0006479//protein methylation;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0032418//lysosome localization;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000119820	15.612	12.512	17.446	15.779	9.933	18.249	1151	968	853	699	762	855	YIPF4	Yip1 domain family member 4 [Source:HGNC Symbol;Acc:HGNC:28145]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048280//vesicle fusion with Golgi apparatus	--
ENSG00000119844	9.91	8.545	9.715	6.856	7.482	8.113	752	661	521	367	464	453	AFTPH	aftiphilin [Source:HGNC Symbol;Acc:HGNC:25951]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030121//AP-1 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0030276//clathrin binding	GO:0015031//protein transport;GO:0046907//intracellular transport	--
ENSG00000119862	8.349	7.053	7.99	6.228	6.334	9.939	638	567	472	369	428	478	LGALSL	galectin like [Source:HGNC Symbol;Acc:HGNC:25012]	-	-	-	-	-	GO:0005515//protein binding;GO:0030246//carbohydrate binding	-	--
ENSG00000119865	4.609	5.541	4.58	5.845	5.898	4.702	180	218	132	153	195	127	CNRIP1	cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0031718//type 1 cannabinoid receptor binding	GO:0010469//regulation of signaling receptor activity;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000119866	0.741	0.425	0.638	0.704	0.569	0.625	39	24	22	15	28	22	BCL11A	BAF chromatin remodeling complex subunit BCL11A [Source:HGNC Symbol;Acc:HGNC:13221]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0042382//paraspeckles	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001067//transcription regulatory region nucleic acid binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0140297//DNA-binding transcription factor binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0016925//protein sumoylation;GO:0030517//negative regulation of axon extension;GO:0032463//negative regulation of protein homooligomerization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048671//negative regulation of collateral sprouting;GO:0048672//positive regulation of collateral sprouting;GO:0050773//regulation of dendrite development;GO:1903860//negative regulation of dendrite extension;GO:1904800//negative regulation of neuron remodeling;GO:1905232//cellular response to L-glutamate;GO:2000171//negative regulation of dendrite development;GO:2000173//negative regulation of branching morphogenesis of a nerve	zf-C2H2
ENSG00000119878	1.815	1.616	1.91	1.698	1.661	1.96	238	213	185	165	184	187	CRIPT	CXXC repeat containing interactor of PDZ3 domain [Source:HGNC Symbol;Acc:HGNC:14312]	-	-	-	-	GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0045202//synapse	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0030165//PDZ domain binding;GO:0044877//protein-containing complex binding;GO:0097110//scaffold protein binding	GO:0031122//cytoplasmic microtubule organization;GO:0035372//protein localization to microtubule;GO:0045184//establishment of protein localization;GO:1902897//regulation of postsynaptic density protein 95 clustering	--
ENSG00000119888	0.128	0.383	0.261	0.337	0.332	0.088	4	12	6	8	9	2	EPCAM	epithelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:11529]	-	-	-	-	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0001657//ureteric bud development;GO:0008284//positive regulation of cell population proliferation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048863//stem cell differentiation;GO:0098609//cell-cell adhesion;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000648//positive regulation of stem cell proliferation	--
ENSG00000119899	7.352	6.003	6.98	5.417	5.911	6.28	502	412	352	274	341	312	SLC17A5	solute carrier family 17 member 5 [Source:HGNC Symbol;Acc:HGNC:10933]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12301	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0005351//carbohydrate:proton symporter activity;GO:0015136//sialic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015538//sialic acid:proton symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006865//amino acid transport;GO:0009617//response to bacterium;GO:0015739//sialic acid transport;GO:0034219//carbohydrate transmembrane transport;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000119900	2.194	1.629	1.558	1.489	1.573	2.109	375	284	201	189	228	265	OGFRL1	opioid growth factor receptor like 1 [Source:HGNC Symbol;Acc:HGNC:21378]	-	-	-	-	GO:0016020//membrane	GO:0038023//signaling receptor activity;GO:0140625//opioid growth factor receptor activity	-	--
ENSG00000119906	5.706	4.262	4.555	3.464	3.715	4.574	733	575	391	326	414	377	SLF2	SMC5-SMC6 complex localization factor 2 [Source:HGNC Symbol;Acc:HGNC:17814]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030915//Smc5-Smc6 complex;GO:0035861//site of double-strand break;GO:0043231//intracellular membrane-bounded organelle"	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032204//regulation of telomere maintenance;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:1990166//protein localization to site of double-strand break;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000119912	15.84	13.524	13.574	9.46	10.724	12.536	1738	1546	1105	772	1026	991	IDE	insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K01408	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0003824//catalytic activity;GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043559//insulin binding;GO:0046872//metal ion binding;GO:0140036//ubiquitin-dependent protein binding	GO:0006508//proteolysis;GO:0008152//metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0008340//determination of adult lifespan;GO:0010815//bradykinin catabolic process;GO:0010992//ubiquitin recycling;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0030163//protein catabolic process;GO:0032092//positive regulation of protein binding;GO:0042447//hormone catabolic process;GO:0043171//peptide catabolic process;GO:0044257//cellular protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0046718//viral entry into host cell;GO:0050435//amyloid-beta metabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0097242//amyloid-beta clearance;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1901142//insulin metabolic process;GO:1901143//insulin catabolic process;GO:1903715//regulation of aerobic respiration	--
ENSG00000119913	0	0	0	0	0	0	0	0	0	0	0	0	TECTB	tectorin beta [Source:HGNC Symbol;Acc:HGNC:11721]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005201//extracellular matrix structural constituent	-	--
ENSG00000119915	0.034	0.103	0	0.232	0.285	0.047	1	3	0	5	7	1	ELOVL3	ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10248;K10248;K10248;K10248	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000119917	2.047	2.301	2.282	2.403	1.531	2.194	103	117	85	90	65	81	IFIT3	interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha;GO:0043066//negative regulation of apoptotic process;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000119919	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-3	NK2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:7836]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001776//leukocyte homeostasis;GO:0002317//plasma cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006641//triglyceride metabolic process;GO:0006955//immune response;GO:0008150//biological_process;GO:0009791//post-embryonic development;GO:0022612//gland morphogenesis;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0030225//macrophage differentiation;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0048537//mucosa-associated lymphoid tissue development;GO:0048541//Peyer's patch development;GO:0048565//digestive tract development;GO:0048621//post-embryonic digestive tract morphogenesis;GO:0050900//leukocyte migration"	Homeobox
ENSG00000119922	2.129	3.184	2.2	3.016	2.195	2.327	143	192	107	133	138	106	IFIT2	interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0008637//apoptotic mitochondrial changes;GO:0009615//response to virus;GO:0032091//negative regulation of protein binding;GO:0035457//cellular response to interferon-alpha;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000119927	4.734	4.687	4.38	3.527	4.528	3.535	624	621	426	344	504	338	GPAM	"glycerol-3-phosphate acyltransferase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:24865]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K00629;K00629;K00629	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0110165//cellular anatomical entity	GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0102420//sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	GO:0001817//regulation of cytokine production;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0009749//response to glucose;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0040018//positive regulation of multicellular organism growth;GO:0042104//positive regulation of activated T cell proliferation;GO:0044255//cellular lipid metabolic process;GO:0051607//defense response to virus;GO:0055089//fatty acid homeostasis;GO:0055091//phospholipid homeostasis;GO:0070236//negative regulation of activation-induced cell death of T cells	--
ENSG00000119929	4.652	4.124	3.945	4.26	4.683	4.895	115	105	77	75	91	86	CUTC	cutC copper transporter [Source:HGNC Symbol;Acc:HGNC:24271]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006825//copper ion transport;GO:0051262//protein tetramerization;GO:0055070//copper ion homeostasis	--
ENSG00000119938	2.277	1.963	1.927	2.997	2.066	1.956	120	104	75	117	92	75	PPP1R3C	protein phosphatase 1 regulatory subunit 3C [Source:HGNC Symbol;Acc:HGNC:9293]	Organismal Systems;Human Diseases	Endocrine system;Endocrine and metabolic disease	ko04910//Insulin signaling pathway;ko04931//Insulin resistance	K07189;K07189	GO:0000164//protein phosphatase type 1 complex;GO:0005829//cytosol	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019903//protein phosphatase binding;GO:2001069//glycogen binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0006470//protein dephosphorylation	--
ENSG00000119943	3.861	4.007	3.84	3.636	4.175	3.112	162	169	119	113	148	95	PYROXD2	pyridine nucleotide-disulphide oxidoreductase domain 2 [Source:HGNC Symbol;Acc:HGNC:23517]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0007005//mitochondrion organization	--
ENSG00000119946	0.719	0.597	0.698	1.096	1.021	1.197	85	71	61	96	102	103	CNNM1	cyclin and CBS domain divalent metal cation transport mediator 1 [Source:HGNC Symbol;Acc:HGNC:102]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0010960//magnesium ion homeostasis;GO:0055085//transmembrane transport	--
ENSG00000119950	9.579	7.54	8.86	6.837	6.493	5.953	387	336	224	181	208	172	MXI1	"MAX interactor 1, dimerization protein [Source:HGNC Symbol;Acc:HGNC:7534]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	bHLH
ENSG00000119953	6.902	7.103	6.455	7.236	6.652	5.685	373	397	270	267	290	232	SMNDC1	survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16900]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12839	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing"	--
ENSG00000119965	4.005	3.31	3.563	3.888	3.683	4.527	242	201	159	174	188	199	C10orf88	chromosome 10 open reading frame 88 [Source:HGNC Symbol;Acc:HGNC:25822]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	-	--
ENSG00000119969	4.725	4.562	2.035	1.646	1.321	1.22	252	167	105	56	60	63	HELLS	"helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861]"	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005721//pericentric heterochromatin"	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0001655//urogenital system development;GO:0001822//kidney development;GO:0006306//DNA methylation;GO:0006338//chromatin remodeling;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0007049//cell cycle;GO:0010216//maintenance of DNA methylation;GO:0031507//heterochromatin assembly;GO:0031508//pericentric heterochromatin assembly;GO:0043066//negative regulation of apoptotic process;GO:0046651//lymphocyte proliferation;GO:0051301//cell division;GO:1990830//cellular response to leukemia inhibitory factor;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000119973	0	0	0	0	0	0	0	0	0	0	0	0	PRLHR	prolactin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4464]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04314	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007565//female pregnancy;GO:0007631//feeding behavior;GO:0042445//hormone metabolic process	--
ENSG00000119977	42.33	49.929	49.323	43.595	43.341	40.701	1883	2129	1569	1465	1575	1322	TCTN3	tectonic family member 3 [Source:HGNC Symbol;Acc:HGNC:24519]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0043065//positive regulation of apoptotic process;GO:0060271//cilium assembly	--
ENSG00000119979	24.683	21.744	23.3	22.851	20.945	23.661	1234	1093	860	857	893	866	DENND10	DENN domain containing 10 [Source:HGNC Symbol;Acc:HGNC:31793]	-	-	-	-	GO:0005768//endosome;GO:0005770//late endosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding	GO:0015031//protein transport;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0050790//regulation of catalytic activity;GO:2000641//regulation of early endosome to late endosome transport	--
ENSG00000119986	7.468	6.593	9.97	10.319	8.134	8.722	213	189	210	218	196	181	AVPI1	arginine vasopressin induced 1 [Source:HGNC Symbol;Acc:HGNC:30898]	-	-	-	-	-	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000120008	14.947	13.526	13.489	10.382	13.579	13.16	1404	1285	945	727	1061	908	WDR11	WD repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:13831]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0007507//heart development;GO:0008589//regulation of smoothened signaling pathway;GO:0035264//multicellular organism growth;GO:0060271//cilium assembly;GO:0060322//head development;GO:0099041//vesicle tethering to Golgi	--
ENSG00000120029	7.871	7.632	8.446	8.042	8.019	8.05	632	604	495	469	576	498	ARMH3	armadillo like helical domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25788]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:1903358//regulation of Golgi organization	--
ENSG00000120049	0.046	0.023	0.25	0.15	0.331	0.095	2	1	8	3	7	3	KCNIP2	potassium voltage-gated channel interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:15522]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030425//dendrite;GO:0034705//potassium channel complex;GO:0045202//synapse	GO:0005244//voltage-gated ion channel activity;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005267//potassium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0046923//ER retention sequence binding;GO:0047485//protein N-terminus binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0008016//regulation of heart contraction;GO:0034765//regulation of ion transmembrane transport;GO:0045163//clustering of voltage-gated potassium channels;GO:0071805//potassium ion transmembrane transport;GO:0086009//membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0097623//potassium ion export across plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport;GO:1903766//positive regulation of potassium ion export across plasma membrane;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000120051	0.059	0.029	0.368	0.02	0.123	0.02	4	2	3	1	7	1	CFAP58	cilia and flagella associated protein 58 [Source:HGNC Symbol;Acc:HGNC:26676]	-	-	-	-	GO:0005615//extracellular space;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece	GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0007288//sperm axoneme assembly;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0120229//protein localization to motile cilium;GO:0120316//sperm flagellum assembly;GO:0120317//sperm mitochondrial sheath assembly	--
ENSG00000120053	27.25	26.771	31.319	33.201	30.379	38.658	1118	1104	949	1009	1053	1154	GOT1	glutamic-oxaloacetic transaminase 1 [Source:HGNC Symbol;Acc:HGNC:4432]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko00350//Tyrosine metabolism;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism;ko00360//Phenylalanine metabolism;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0004609//phosphatidylserine decarboxylase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0047801//L-cysteine:2-oxoglutarate aminotransferase activity	GO:0006103//2-oxoglutarate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006114//glycerol biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0006531//aspartate metabolic process;GO:0006532//aspartate biosynthetic process;GO:0006533//aspartate catabolic process;GO:0006536//glutamate metabolic process;GO:0007219//Notch signaling pathway;GO:0008652//cellular amino acid biosynthetic process;GO:0009058//biosynthetic process;GO:0019550//glutamate catabolic process to aspartate;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0032869//cellular response to insulin stimulus;GO:0051384//response to glucocorticoid;GO:0055089//fatty acid homeostasis	--
ENSG00000120054	0	0	0	0	0	0	0	0	0	0	0	0	CPN1	carboxypeptidase N subunit 1 [Source:HGNC Symbol;Acc:HGNC:2312]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0010815//bradykinin catabolic process;GO:0016485//protein processing;GO:0051384//response to glucocorticoid	--
ENSG00000120055	0.197	0.065	0.089	0.31	0.117	0.135	6	2	2	7	3	3	C10orf95	chromosome 10 open reading frame 95 [Source:HGNC Symbol;Acc:HGNC:25880]	-	-	-	-	-	-	-	--
ENSG00000120057	493.354	484.666	592.625	635.584	583.679	654.934	19269	19027	17095	18388	19260	18612	SFRP5	secreted frizzled related protein 5 [Source:HGNC Symbol;Acc:HGNC:10779]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K02222	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0017147//Wnt-protein binding	GO:0006915//apoptotic process;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0016055//Wnt signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0051898//negative regulation of protein kinase B signaling;GO:0060070//canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000057//negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	--
ENSG00000120063	34.568	29.318	26.966	22.656	22.625	24.941	3864	3243	2320	1855	2078	2196	GNA13	G protein subunit alpha 13 [Source:HGNC Symbol;Acc:HGNC:4381]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Signal transduction;Circulatory system;Immune system;Signal transduction;Endocrine system;Nervous system	"ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04730//Long-term depression"	K04639;K04639;K04639;K04639;K04639;K04639;K04639;K04639;K04639;K04639;K04639;K04639	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031526//brush border membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031752//D5 dopamine receptor binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001701//in utero embryonic development;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007266//Rho protein signal transduction;GO:0008217//regulation of blood pressure;GO:0008360//regulation of cell shape;GO:0010259//multicellular organism aging;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0030334//regulation of cell migration;GO:0031584//activation of phospholipase D activity;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration	--
ENSG00000120068	0	0	0	0	0	0	0	0	0	0	0	0	HOXB8	homeobox B8 [Source:HGNC Symbol;Acc:HGNC:5119]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007625//grooming behavior;GO:0008344//adult locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0019233//sensory perception of pain;GO:0021516//dorsal spinal cord development;GO:0045638//negative regulation of myeloid cell differentiation;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis"	Homeobox
ENSG00000120071	9.213	10.959	9.221	8.013	9.695	9.99	875	893	602	515	699	663	KANSL1	KAT8 regulatory NSL complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24565]	-	-	-	-	"GO:0000123//histone acetyltransferase complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0044545//NSL complex;GO:0071339//MLL1 complex"	GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding	"GO:0006325//chromatin organization;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000120075	0	0	0	0	0	0	0	0	0	0	0	0	HOXB5	homeobox B5 [Source:HGNC Symbol;Acc:HGNC:5116]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0045446//endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000120088	0	0	0	0	0	0	0	0	0	0	0	0	CRHR1	corticotropin releasing hormone receptor 1 [Source:HGNC Symbol;Acc:HGNC:2357]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome;ko04730//Long-term depression	K04578;K04578;K04578;K04578	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043005//neuron projection	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0015056//corticotrophin-releasing factor receptor activity;GO:0017046//peptide hormone binding;GO:0043404//corticotropin-releasing hormone receptor activity;GO:0051424//corticotropin-releasing hormone binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007565//female pregnancy;GO:0007567//parturition;GO:0009755//hormone-mediated signaling pathway;GO:0010578//regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway;GO:0051458//corticotropin secretion;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:2000852//regulation of corticosterone secretion	--
ENSG00000120093	0	0.018	0	0	0	0	0	1	0	0	0	0	HOXB3	homeobox B3 [Source:HGNC Symbol;Acc:HGNC:5114]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0021546//rhombomere development;GO:0021615//glossopharyngeal nerve morphogenesis;GO:0030878//thyroid gland development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0050767//regulation of neurogenesis;GO:0051216//cartilage development;GO:0060216//definitive hemopoiesis;GO:0060324//face development"	Homeobox
ENSG00000120094	0	0	0	0	0	0	0	0	0	0	0	0	HOXB1	homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09301	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0021546//rhombomere development;GO:0021570//rhombomere 4 development;GO:0021571//rhombomere 5 development;GO:0021612//facial nerve structural organization;GO:0021754//facial nucleus development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000120129	13.915	12.128	8.529	13.16	12.558	14.483	581	509	263	407	443	440	DUSP1	dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Neurodegenerative disease;Cardiovascular disease;Nervous system	ko04010//MAPK signaling pathway;ko05012//Parkinson disease;ko05418//Fluid shear stress and atherosclerosis;ko04726//Serotonergic synapse	K21278;K21278;K21278;K21278	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0001706//endoderm formation;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0007162//negative regulation of cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0051447//negative regulation of meiotic cell cycle;GO:0070262//peptidyl-serine dephosphorylation;GO:0090027//negative regulation of monocyte chemotaxis;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:1903753//negative regulation of p38MAPK cascade;GO:1990869//cellular response to chemokine	--
ENSG00000120137	28.019	20.948	21.596	19.447	20.24	23.901	5971	4487	3399	2971	3644	3706	PANK3	pantothenate kinase 3 [Source:HGNC Symbol;Acc:HGNC:19365]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K09680;K09680	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004594//pantothenate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019842//vitamin binding;GO:0042803//protein homodimerization activity;GO:1905502//acetyl-CoA binding	GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000120149	1.513	1.738	1.811	2.214	1.775	1.298	66	70	58	59	64	43	MSX2	msh homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7392]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K09341	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0002063//chondrocyte development;GO:0002076//osteoblast development;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003161//cardiac conduction system development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003416//endochondral bone growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032792//negative regulation of CREB transcription factor activity;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035313//wound healing, spreading of epidermal cells;GO:0035880//embryonic nail plate morphogenesis;GO:0042060//wound healing;GO:0042476//odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045599//negative regulation of fat cell differentiation;GO:0045617//negative regulation of keratinocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048598//embryonic morphogenesis;GO:0048863//stem cell differentiation;GO:0051216//cartilage development;GO:0051795//positive regulation of timing of catagen;GO:0060346//bone trabecula formation;GO:0060349//bone morphogenesis;GO:0060363//cranial suture morphogenesis;GO:0060364//frontal suture morphogenesis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0061180//mammary gland epithelium development;GO:0061312//BMP signaling pathway involved in heart development;GO:0070166//enamel mineralization;GO:0071363//cellular response to growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0090427//activation of meiosis;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2001055//positive regulation of mesenchymal cell apoptotic process"	Homeobox
ENSG00000120156	0.106	0.17	0	0.046	0.087	0.091	7	8	0	3	6	3	TEK	TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Immune disease;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05323//Rheumatoid arthritis;ko04066//HIF-1 signaling pathway	K05121;K05121;K05121;K05121;K05121;K05121	GO:0001725//stress fiber;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0034451//centriolar satellite;GO:0043235//receptor complex;GO:0045121//membrane raft	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001935//endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling;GO:0007507//heart development;GO:0010595//positive regulation of endothelial cell migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0033674//positive regulation of kinase activity;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043066//negative regulation of apoptotic process;GO:0043114//regulation of vascular permeability;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045766//positive regulation of angiogenesis;GO:0046777//protein autophosphorylation;GO:0048014//Tie signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0051894//positive regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0060216//definitive hemopoiesis;GO:0060347//heart trabecula formation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072012//glomerulus vasculature development;GO:1902533//positive regulation of intracellular signal transduction;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:2000351//regulation of endothelial cell apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000120158	6.696	6.779	5.662	5.294	7.216	5.755	269	265	170	163	212	179	RCL1	RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11108	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003824//catalytic activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000479//endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006396//RNA processing;GO:0008150//biological_process;GO:0042254//ribosome biogenesis"	--
ENSG00000120159	12.971	14.577	12.623	11.503	11.625	11.882	585	616	427	377	425	400	CAAP1	caspase activity and apoptosis inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:25834]	-	-	-	-	-	-	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000120160	0	0	0	0	0	0	0	0	0	0	0	0	EQTN	equatorin [Source:HGNC Symbol;Acc:HGNC:1359]	-	-	-	-	GO:0002079//inner acrosomal membrane;GO:0002080//acrosomal membrane;GO:0002081//outer acrosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0006897//endocytosis;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0060478//acrosomal vesicle exocytosis	--
ENSG00000120162	1.048	0.806	0.896	1.395	1.742	1.328	141	109	89	139	198	130	MOB3B	MOB kinase activator 3B [Source:HGNC Symbol;Acc:HGNC:23825]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity;GO:0035330//regulation of hippo signaling	--
ENSG00000120210	0	0	0	0	0	0	0	0	0	0	0	0	INSL6	insulin like 6 [Source:HGNC Symbol;Acc:HGNC:6089]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0008150//biological_process	--
ENSG00000120211	0	0	0	0	0	0	0	0	0	0	0	0	INSL4	insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:1901384//positive regulation of chorionic trophoblast cell proliferation	--
ENSG00000120215	12.931	10.863	14.159	11.052	11.425	13.707	334	352	274	234	285	280	MLANA	melan-A [Source:HGNC Symbol;Acc:HGNC:7124]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome	GO:0005515//protein binding	-	--
ENSG00000120217	0.65	0.541	0.323	0.35	0.386	0.739	49	41	18	18	24	40	CD274	CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635]	Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Cancer: overview	ko04514//Cell adhesion molecules;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06745;K06745	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002845//positive regulation of tolerance induction to tumor cell;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0031295//T cell costimulation;GO:0032689//negative regulation of interferon-gamma production;GO:0032693//negative regulation of interleukin-10 production;GO:0032733//positive regulation of interleukin-10 production;GO:0034097//response to cytokine;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0046007//negative regulation of activated T cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:1901998//toxin transport;GO:1903556//negative regulation of tumor necrosis factor superfamily cytokine production;GO:1905404//positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2001186//negative regulation of CD8-positive, alpha-beta T cell activation"	--
ENSG00000120235	0	0	0	0	0	0	0	0	0	0	0	0	IFNA6	interferon alpha 6 [Source:HGNC Symbol;Acc:HGNC:5427]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0051707//response to other organism;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000120242	0	0	0	0	0	0	0	0	0	0	0	0	IFNA8	interferon alpha 8 [Source:HGNC Symbol;Acc:HGNC:5429]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000120251	0.389	0.316	1.085	0.839	2.845	1.798	40	37	23	40	61	40	GRIA2	glutamate ionotropic receptor AMPA type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4572]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Nervous system;Neurodegenerative disease;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko04024//cAMP signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04730//Long-term depression;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198;K05198	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0032279//asymmetric synapse;GO:0032281//AMPA glutamate receptor complex;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098794//postsynapse;GO:0098839//postsynaptic density membrane;GO:0098843//postsynaptic endocytic zone;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004971//AMPA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0038023//signaling receptor activity	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic"	--
ENSG00000120253	6.389	6.663	5.751	5.699	5.031	5.833	477	476	326	289	295	278	NUP43	nucleoporin 43 [Source:HGNC Symbol;Acc:HGNC:21182]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14305;K14305	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0031080//nuclear pore outer ring"	GO:0005515//protein binding	GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051301//cell division	--
ENSG00000120254	7.946	6.873	6.666	5.366	5.37	5.169	571	478	328	208	270	236	MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [Source:HGNC Symbol;Acc:HGNC:21055]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K13402;K13402	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042803//protein homodimerization activity	GO:0001843//neural tube closure;GO:0006730//one-carbon metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0009257//10-formyltetrahydrofolate biosynthetic process;GO:0015942//formate metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0048702//embryonic neurocranium morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis	--
ENSG00000120256	6.228	6	7.494	8.391	7.298	6.691	467	452	415	466	461	366	LRP11	LDL receptor related protein 11 [Source:HGNC Symbol;Acc:HGNC:16936]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0051219//phosphoprotein binding	GO:0009408//response to heat;GO:0009409//response to cold;GO:0009414//response to water deprivation;GO:0009612//response to mechanical stimulus;GO:0033555//multicellular organismal response to stress;GO:0035902//response to immobilization stress;GO:0042594//response to starvation	--
ENSG00000120262	0.563	0.597	0.431	0.356	0.43	0.537	62	66	35	29	40	43	CCDC170	coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization	--
ENSG00000120265	32.41	31.591	30.242	25.97	26.09	31.481	1168	1155	811	707	798	824	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8728]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0045296//cadherin binding	GO:0006464//cellular protein modification process;GO:0006479//protein methylation;GO:0006807//nitrogen compound metabolic process;GO:0030091//protein repair;GO:0032259//methylation;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000120278	0.354	0.346	0.59	0.467	0.514	0.584	53	52	64	51	65	38	PLEKHG1	pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000120279	0.04	0	0	0	0.024	0	2	0	0	0	1	0	MYCT1	MYC target 1 [Source:HGNC Symbol;Acc:HGNC:23172]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000120280	0	0	0	0	0	0	0	0	0	0	0	0	TASL	TLR adaptor interacting with endolysosomal SLC15A4 [Source:HGNC Symbol;Acc:HGNC:25667]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0036020//endolysosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0002376//immune system process;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0034161//positive regulation of toll-like receptor 8 signaling pathway;GO:0035751//regulation of lysosomal lumen pH;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response	--
ENSG00000120289	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB4	MAGE family member B4 [Source:HGNC Symbol;Acc:HGNC:6811]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000120306	77.016	74.497	86.639	87.66	83.719	106.101	1262	1227	1047	1064	1159	1265	CYSTM1	cysteine rich transmembrane module containing 1 [Source:HGNC Symbol;Acc:HGNC:30239]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000120314	6.099	5.58	5.889	6.982	5.368	6.582	451.17	405.1	316.81	378.2	340.38	347.73	WDR55	WD repeat domain 55 [Source:HGNC Symbol;Acc:HGNC:25971]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0008150//biological_process	--
ENSG00000120318	3.527	3.31	3.5	3.265	3.287	3.785	367	361	273	240	271	290	ARAP3	"ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097]"	Cellular Processes;Environmental Information Processing;Environmental Information Processing	Transport and catabolism;Signal transduction;Signal transduction	ko04144//Endocytosis;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway	K12490;K12490;K12490	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0042995//cell projection	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding"	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0016192//vesicle-mediated transport;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000120322	0.912	0.954	0.573	1.032	0.887	0.605	52.03	54.68	24.16	43.59	42.76	25.1	PCDHB8	protocadherin beta 8 [Source:HGNC Symbol;Acc:HGNC:8693]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000120324	2.356	2.18	3.089	2.151	2.434	2.474	161.03	149.79	155.94	108.91	140.56	123.04	PCDHB10	protocadherin beta 10 [Source:HGNC Symbol;Acc:HGNC:8681]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000120327	2.781	2.718	2.959	2.761	2.258	2.35	201.7	201.15	157	161	132.08	131.35	PCDHB14	protocadherin beta 14 [Source:HGNC Symbol;Acc:HGNC:8685]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000120328	0.085	0.012	0.033	0	0.03	0	6.4	1	1	0	2.04	0	PCDHB12	protocadherin beta 12 [Source:HGNC Symbol;Acc:HGNC:8683]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000120329	0	0	0.092	0	0	0	0	0	2	0	0	0	SLC25A2	solute carrier family 25 member 2 [Source:HGNC Symbol;Acc:HGNC:22921]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000064//L-ornithine transmembrane transporter activity;GO:0005515//protein binding	GO:0000050//urea cycle;GO:1990575//mitochondrial L-ornithine transmembrane transport	--
ENSG00000120332	0	0	0	0.031	0	0	0	0	0	2	0	0	TNN	tenascin N [Source:HGNC Symbol;Acc:HGNC:22942]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04512//ECM-receptor interaction	K06252;K06252;K06252;K06252;K06252	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0062023//collagen-containing extracellular matrix;GO:0090733//tenascin complex;GO:0097442//CA3 pyramidal cell dendrite;GO:1990026//hippocampal mossy fiber expansion	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002076//osteoblast development;GO:0007160//cell-matrix adhesion;GO:0007409//axonogenesis;GO:0010976//positive regulation of neuron projection development;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0033689//negative regulation of osteoblast proliferation;GO:0045668//negative regulation of osteoblast differentiation;GO:0070593//dendrite self-avoidance;GO:1903010//regulation of bone development;GO:1903672//positive regulation of sprouting angiogenesis;GO:1905240//negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation;GO:1905899//regulation of smooth muscle tissue development;GO:1990138//neuron projection extension;GO:2001223//negative regulation of neuron migration	--
ENSG00000120333	12.713	11.459	10.721	13.715	12.991	13.602	473	474	342	390	414	385	MRPS14	mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:14049]	Genetic Information Processing	Translation	ko03010//Ribosome	K02954	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0031965//nuclear membrane	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000120334	1.205	1.512	1.701	1.771	1.107	1.252	63.13	84.38	60	62	46	41.42	CENPL	centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0005515//protein binding	-	--
ENSG00000120337	0.035	0.035	0.048	0.142	0.062	0.097	2	2	2	6	3	4	TNFSF18	TNF superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11932]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05479	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002309//T cell proliferation involved in immune response;GO:0002376//immune system process;GO:0002687//positive regulation of leukocyte migration;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042129//regulation of T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0045785//positive regulation of cell adhesion;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000120341	0.664	0.521	0.734	0.684	0.56	0.644	59	41	46	45	44	38	SEC16B	"SEC16 homolog B, endoplasmic reticulum export factor [Source:HGNC Symbol;Acc:HGNC:30301]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0007031//peroxisome organization;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016559//peroxisome fission;GO:0046907//intracellular transport;GO:0048208//COPII vesicle coating;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0070973//protein localization to endoplasmic reticulum exit site	--
ENSG00000120370	7.206	6.571	7.647	3.425	3.957	5.268	254	247	196	116	123	141	GORAB	"golgin, RAB6 interacting [Source:HGNC Symbol;Acc:HGNC:25676]"	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K19748	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0031069//hair follicle morphogenesis;GO:1901622//positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1905515//non-motile cilium assembly	--
ENSG00000120436	0	0	0	0	0	0	0	0	0	0	0	0	GPR31	G protein-coupled receptor 31 [Source:HGNC Symbol;Acc:HGNC:4486]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0045125//bioactive lipid receptor activity;GO:0050544//arachidonic acid binding	GO:0002237//response to molecule of bacterial origin;GO:0002931//response to ischemia;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010447//response to acidic pH;GO:0050728//negative regulation of inflammatory response;GO:0050778//positive regulation of immune response	--
ENSG00000120437	23.294	20.405	21.985	30.071	24.838	27.929	734.42	646.62	511.92	702.27	661.6	640.69	ACAT2	acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Metabolism of terpenoids and polyketides	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko04975//Fat digestion and absorption;ko00630//Glyoxylate and dicarboxylate metabolism;ko00650//Butanoate metabolism;ko00900//Terpenoid backbone biosynthesis"	K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626;K00626	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000120438	95.49	92.365	98.243	106.179	102.641	99.387	4046.58	3925.38	3119.08	3359.73	3639.4	3102.31	TCP1	t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000792//heterochromatin;GO:0001669//acrosomal vesicle;GO:0002199//zona pellucida receptor complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0044053//translocation of peptides or proteins into host cell cytoplasm;GO:0050821//protein stabilization;GO:0051973//positive regulation of telomerase activity;GO:0061077//chaperone-mediated protein folding;GO:0090666//scaRNA localization to Cajal body;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:2000109//regulation of macrophage apoptotic process	--
ENSG00000120440	0	0	0	0	0	0	0	0	0	0	0	0	TTLL2	tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211]	-	-	-	-	GO:0005929//cilium	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation	--
ENSG00000120451	37.536	33.154	34.597	35.787	38.675	37.628	3599	3664	2739	2498	3131	2567	SNX19	sorting nexin 19 [Source:HGNC Symbol;Acc:HGNC:21532]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding	GO:0002062//chondrocyte differentiation;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0030073//insulin secretion;GO:1990502//dense core granule maturation	--
ENSG00000120457	0.089	0.227	0.336	0.271	0.341	0.187	11	8	15	9	15	15	KCNJ5	potassium inwardly rectifying channel subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:6266]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Endocrine system;Nervous system;Endocrine system;Nervous system;Nervous system;Environmental adaptation;Endocrine system;Substance dependence;Endocrine system	ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko05032//Morphine addiction;ko04929//GnRH secretion	K04999;K04999;K04999;K04999;K04999;K04999;K04999;K04999;K04999	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0099625//ventricular cardiac muscle cell membrane repolarization;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000120458	2.185	2.14	2.522	2.681	2.125	2.536	120	119	100	113	102	99	MSANTD2	Myb/SANT DNA binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26266]	-	-	-	-	-	-	-	--
ENSG00000120471	0	0	0	0	0	0	0	0	0	0	0	0	TP53AIP1	tumor protein p53 regulated apoptosis inducing protein 1 [Source:HGNC Symbol;Acc:HGNC:29984]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04210//Apoptosis;ko04115//p53 signaling pathway	K13773;K13773	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003674//molecular_function	GO:0006915//apoptotic process	--
ENSG00000120498	0	0	0	0	0	0	0	0	0	0	0	0	TEX11	testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000801//central element;GO:0005694//chromosome	GO:0005515//protein binding	GO:0000712//resolution of meiotic recombination intermediates;GO:0006311//meiotic gene conversion;GO:0007060//male meiosis chromosome segregation;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0008584//male gonad development;GO:0009566//fertilization;GO:0043066//negative regulation of apoptotic process;GO:0051026//chiasma assembly;GO:0051321//meiotic cell cycle	--
ENSG00000120500	0	0	0	0	0.208	0	0	0	0	0	2	0	ARR3	arrestin 3 [Source:HGNC Symbol;Acc:HGNC:710]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0045202//synapse	GO:0001664//G protein-coupled receptor binding;GO:0002046//opsin binding;GO:0005515//protein binding;GO:0051219//phosphoprotein binding	GO:0001932//regulation of protein phosphorylation;GO:0002031//G protein-coupled receptor internalization;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0050896//response to stimulus	--
ENSG00000120509	28.328	27.827	27.072	26.129	26.206	23.437	559	554	396	382	441	342	PDZD11	PDZ domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28034]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0046930//pore complex;GO:0098793//presynapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0007269//neurotransmitter secretion;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0046931//pore complex assembly;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000120519	2.013	1.988	2.324	2.674	2.375	1.746	143	135	94	93	104	99	SLC10A7	solute carrier family 10 member 7 [Source:HGNC Symbol;Acc:HGNC:23088]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0015125//bile acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0015721//bile acid and bile salt transport;GO:0030210//heparin biosynthetic process;GO:0034436//glycoprotein transport;GO:0048193//Golgi vesicle transport;GO:0055085//transmembrane transport;GO:0060348//bone development	--
ENSG00000120526	6.111	4.502	5.116	4.397	3.69	4.291	332	251	204	183	163	179	NUDCD1	NudC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24306]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002376//immune system process	--
ENSG00000120533	19.75	15.081	14.301	12.923	12.236	15.053	511	518	373	336	355	360	ENY2	ENY2 transcription and export complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:24449]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0033276//transcription factor TFTC complex;GO:0044615//nuclear pore nuclear basket;GO:0070390//transcription export complex 2;GO:0071819//DUBm complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006406//mRNA export from nucleus;GO:0015031//protein transport;GO:0016578//histone deubiquitination;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051028//mRNA transport"	--
ENSG00000120539	2.051	2.417	1.746	1.811	1.226	1.729	142.14	164.58	88.67	79.84	78.27	83.46	MASTL	microtubule associated serine/threonine kinase like [Source:HGNC Symbol;Acc:HGNC:19042]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0032154//cleavage furrow	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051721//protein phosphatase 2A binding;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007147//female meiosis II;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035556//intracellular signal transduction;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:1904668//positive regulation of ubiquitin protein ligase activity	--
ENSG00000120549	16.626	13.233	12.324	10.765	10.079	10.413	1920	1751	1290	875	1227	1015	KIAA1217	KIAA1217 [Source:HGNC Symbol;Acc:HGNC:25428]	-	-	-	-	GO:0005737//cytoplasm;GO:0110165//cellular anatomical entity	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0048706//embryonic skeletal system development	--
ENSG00000120563	0	0	0	0	0	0	0	0	0	0	0	0	LYZL1	lysozyme like 1 [Source:HGNC Symbol;Acc:HGNC:30502]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13915	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process	--
ENSG00000120594	18.088	16.52	10.169	9.146	11.272	9.397	2978	2355	1190	981	1424	1025	PLXDC2	plexin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21013]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000120616	7.276	6.987	7.297	4.668	5.545	5.298	526	527	405	257	354	288	EPC1	enhancer of polycomb homolog 1 [Source:HGNC Symbol;Acc:HGNC:19876]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0032777//Piccolo NuA4 histone acetyltransferase complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0140463//chromatin-protein adaptor	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000724//double-strand break repair via homologous recombination;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000120645	14.157	13.874	12.492	13.75	12.647	12.071	1676	1757	1126	1224	1370	1077	IQSEC3	IQ motif and Sec7 domain ArfGEF 3 [Source:HGNC Symbol;Acc:HGNC:29193]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12495	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse;GO:0098690//glycinergic synapse;GO:0098982//GABA-ergic synapse;GO:0099629//postsynaptic specialization of symmetric synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000120647	2.624	1.823	2.115	1.259	1.702	2.335	102	82	73	45	68	79	CCDC77	coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203]	-	-	-	-	GO:0005813//centrosome;GO:0016020//membrane	-	-	--
ENSG00000120656	10.979	10.562	11.061	10.005	9.716	9.969	283	275	208	174	209	184	TAF12	TATA-box binding protein associated factor 12 [Source:HGNC Symbol;Acc:HGNC:11545]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03126	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex;GO:0046695//SLIK (SAGA-like) complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity;GO:0140297//DNA-binding transcription factor binding	"GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0016573//histone acetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000120658	3.636	3.746	3.357	2.394	2.956	2.386	228	238	156	115	157	116	ENOX1	ecto-NOX disulfide-thiol exchanger 1 [Source:HGNC Symbol;Acc:HGNC:25474]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003756//protein disulfide isomerase activity;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity	GO:0007624//ultradian rhythm;GO:0048511//rhythmic process	--
ENSG00000120659	0	0	0	0	0	0	0	0	0	0	0	0	TNFSF11	TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Cancer: overview;Signal transduction;Immune disease;Cancer: specific types;Development and regeneration;Endocrine system;Endocrine system	"ko04060//Cytokine-cytokine receptor interaction;ko05207//Chemical carcinogenesis - receptor activation;ko04064//NF-kappa B signaling pathway;ko05323//Rheumatoid arthritis;ko05224//Breast cancer;ko04380//Osteoclast differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04917//Prolactin signaling pathway"	K05473;K05473;K05473;K05473;K05473;K05473;K05473;K05473	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0042802//identical protein binding	GO:0001503//ossification;GO:0002158//osteoclast proliferation;GO:0002548//monocyte chemotaxis;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0019722//calcium-mediated signaling;GO:0030154//cell differentiation;GO:0030316//osteoclast differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0036035//osteoclast development;GO:0038001//paracrine signaling;GO:0042327//positive regulation of phosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0044691//tooth eruption;GO:0045453//bone resorption;GO:0045670//regulation of osteoclast differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0050870//positive regulation of T cell activation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051466//positive regulation of corticotropin-releasing hormone secretion;GO:0051897//positive regulation of protein kinase B signaling;GO:0055074//calcium ion homeostasis;GO:0060348//bone development;GO:0060749//mammary gland alveolus development;GO:0070371//ERK1 and ERK2 cascade;GO:0071812//positive regulation of fever generation by positive regulation of prostaglandin secretion;GO:0071847//TNFSF11-mediated signaling pathway;GO:0071848//positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling;GO:1902533//positive regulation of intracellular signal transduction;GO:1904616//regulation of actin binding;GO:1990830//cellular response to leukemia inhibitory factor;GO:2001206//positive regulation of osteoclast development	--
ENSG00000120662	1.762	2.307	2.402	2.534	2.036	3.301	70	74	53	51	61	78	MTRF1	mitochondrial translation release factor 1 [Source:HGNC Symbol;Acc:HGNC:7469]	-	-	-	-	GO:0005739//mitochondrion	GO:0003747//translation release factor activity	GO:0006412//translation;GO:0006415//translational termination;GO:0006449//regulation of translational termination;GO:0070126//mitochondrial translational termination	--
ENSG00000120669	0.618	0.564	0.676	0.357	0.361	0.347	27.25	24.97	22	11.65	13.45	11.12	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2 [Source:HGNC Symbol;Acc:HGNC:26026]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0009994//oocyte differentiation;GO:0030154//cell differentiation;GO:0048477//oogenesis"	bHLH
ENSG00000120675	7.175	6.173	6.774	6.518	5.638	7.364	1110	960	774	747	737	829	DNAJC15	DnaJ heat shock protein family (Hsp40) member C15 [Source:HGNC Symbol;Acc:HGNC:20325]	-	-	-	-	"GO:0001405//PAM complex, Tim23 associated import motor;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane"	GO:0001671//ATPase activator activity;GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0009267//cellular response to starvation;GO:0015031//protein transport;GO:0019216//regulation of lipid metabolic process;GO:0030150//protein import into mitochondrial matrix;GO:0031333//negative regulation of protein-containing complex assembly;GO:1902957//negative regulation of mitochondrial electron transport, NADH to ubiquinone"	--
ENSG00000120685	6.273	5.198	5.996	4.735	5.751	7.218	673	561	476	377	522	564	PROSER1	proline and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:20291]	-	-	-	-	-	-	-	--
ENSG00000120686	18.618	18.161	18.672	15.414	14.338	18.77	1173	1079	772	698	732	802	UFM1	ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding	GO:0007420//brain development;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0042308//negative regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0061709//reticulophagy;GO:0071569//protein ufmylation;GO:1990592//protein K69-linked ufmylation	--
ENSG00000120688	3.654	3.716	3.417	2.289	3.417	3.135	181	185	125	84	143	113	WBP4	WW domain binding protein 4 [Source:HGNC Symbol;Acc:HGNC:12739]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0070064//proline-rich region binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000120690	12.594	10.869	11.957	11.789	11.262	10.695	662	581	505	445	482	441	ELF1	E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316]	Cellular Processes	Cell growth and death	ko04214//Apoptosis - fly	K09428	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001817//regulation of cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051171//regulation of nitrogen compound metabolic process;GO:0060255//regulation of macromolecule metabolic process;GO:0080090//regulation of primary metabolic process"	ETS
ENSG00000120693	1.898	1.571	0.951	1.719	2.236	2.276	175	169	81	124	184	159	SMAD9	SMAD family member 9 [Source:HGNC Symbol;Acc:HGNC:6774]	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K16791;K16791	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071141//SMAD protein complex;GO:0071144//heteromeric SMAD protein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070411//I-SMAD binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0071773//cellular response to BMP stimulus;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090287//regulation of cellular response to growth factor stimulus;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus"	MH1
ENSG00000120694	34.872	28.448	26.965	22.154	23.295	27.582	2586	2128	1470	1244	1482	1494	HSPH1	heat shock protein family H (Hsp110) member 1 [Source:HGNC Symbol;Acc:HGNC:16969]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09485	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen	GO:0000166//nucleotide binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0043014//alpha-tubulin binding	GO:0006986//response to unfolded protein;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051135//positive regulation of NK T cell activation	--
ENSG00000120696	6.093	6.307	6.659	6.315	6.314	6.793	598.51	622.7	483.09	459.54	524	485.56	KBTBD7	kelch repeat and BTB domain containing 7 [Source:HGNC Symbol;Acc:HGNC:25266]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0035020//regulation of Rac protein signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000120697	22.891	24.024	26.211	24.702	22.63	27.4	568	608	479	459	464	500	ALG5	ALG5 dolichyl-phosphate beta-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:20266]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K00729;K00729	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004576//oligosaccharyl transferase activity;GO:0004581//dolichyl-phosphate beta-glucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0007368//determination of left/right symmetry;GO:0018279//protein N-linked glycosylation via asparagine	--
ENSG00000120699	6.532	4.804	6.296	4.363	5.245	6.368	193.85	145.58	131.33	99.67	124.95	135.18	EXOSC8	exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12586	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0101019//nucleolar exosome (RNase complex);GO:1902494//catalytic complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0042802//identical protein binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034473//U1 snRNA 3'-end processing;GO:0034475//U4 snRNA 3'-end processing;GO:0034476//U5 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0051252//regulation of RNA metabolic process;GO:0071028//nuclear mRNA surveillance;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071042//nuclear polyadenylation-dependent mRNA catabolic process"	--
ENSG00000120705	37.178	37.096	33.926	29.979	27.175	35.136	2139	2124	1418	1309	1408	1466	ETF1	eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K03265	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0018444//translation release factor complex	"GO:0003723//RNA binding;GO:0003747//translation release factor activity;GO:0005515//protein binding;GO:0008079//translation termination factor activity;GO:0016149//translation release factor activity, codon specific;GO:0043022//ribosome binding;GO:1990825//sequence-specific mRNA binding"	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002184//cytoplasmic translational termination;GO:0006412//translation;GO:0006415//translational termination;GO:0006449//regulation of translational termination;GO:0006479//protein methylation"	--
ENSG00000120708	12.832	13.812	12.516	5.376	7.007	4.129	717	761	520	224	333	169	TGFBI	transforming growth factor beta induced [Source:HGNC Symbol;Acc:HGNC:11771]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0050840//extracellular matrix binding	GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007601//visual perception;GO:0008283//cell population proliferation;GO:0030198//extracellular matrix organization;GO:0050896//response to stimulus	--
ENSG00000120709	19.522	17.968	21.067	19.307	18.54	24.215	1649	1552	1304	1229	1346	1503	FAM53C	family with sequence similarity 53 member C [Source:HGNC Symbol;Acc:HGNC:1336]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0006606//protein import into nucleus	--
ENSG00000120725	30.589	39.894	35.855	37.892	39.62	35.677	1145	1400	901	960	1112	893	SIL1	SIL1 nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:24624]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14001	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0006613//cotranslational protein targeting to membrane;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000120727	46.275	39.795	44.609	40.423	39.389	39.183	1395	1208	995	903	1005	861	PAIP2	poly(A) binding protein interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17970]	-	-	-	-	GO:0005737//cytoplasm	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0030371//translation repressor activity"	GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0007613//memory;GO:0017148//negative regulation of translation;GO:0045947//negative regulation of translational initiation;GO:1900271//regulation of long-term synaptic potentiation	--
ENSG00000120729	0	0	0	0	0	0	0	0	0	0	0	0	MYOT	myotilin [Source:HGNC Symbol;Acc:HGNC:12399]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030018//Z disc;GO:0030424//axon;GO:0042383//sarcolemma;GO:0043025//neuronal cell body	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0008307//structural constituent of muscle;GO:0051393//alpha-actinin binding	GO:0006936//muscle contraction;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0050808//synapse organization	--
ENSG00000120733	34.509	35.325	35.78	35.316	35.523	33.563	4426	4625	3484	3259	3823	3101	KDM3B	lysine demethylase 3B [Source:HGNC Symbol;Acc:HGNC:1337]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K15601	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003712//transcription coregulator activity;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0140683//histone H3-di/monomethyl-lysine-9 demethylase activity	GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0033169//histone H3-K9 demethylation	--
ENSG00000120738	1.429	1.177	1.394	0.622	0.8	0.253	93	77	67	30	44	12	EGR1	early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Neurodegenerative disease;Infectious disease: viral;Signal transduction;Endocrine system;Endocrine and metabolic disease;Endocrine system	"ko05020//Prion disease;ko05166//Human T-cell leukemia virus 1 infection;ko04371//Apelin signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04912//GnRH signaling pathway"	K09203;K09203;K09203;K09203;K09203;K09203	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0010385//double-stranded methylated DNA binding;GO:0035035//histone acetyltransferase binding;GO:0043565//sequence-specific DNA binding;GO:0044729//hemi-methylated DNA-binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0002931//response to ischemia;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009749//response to glucose;GO:0010628//positive regulation of gene expression;GO:0030217//T cell differentiation;GO:0030509//BMP signaling pathway;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0033233//regulation of protein sumoylation;GO:0035914//skeletal muscle cell differentiation;GO:0042981//regulation of apoptotic process;GO:0044849//estrous cycle;GO:0045475//locomotor rhythm;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046886//positive regulation of hormone biosynthetic process;GO:0048511//rhythmic process;GO:0060086//circadian temperature homeostasis;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071310//cellular response to organic substance;GO:0071480//cellular response to gamma radiation;GO:0071504//cellular response to heparin;GO:0071506//cellular response to mycophenolic acid;GO:0072110//glomerular mesangial cell proliferation;GO:0072303//positive regulation of glomerular metanephric mesangial cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0098759//cellular response to interleukin-8;GO:1901216//positive regulation of neuron death;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1902949//positive regulation of tau-protein kinase activity;GO:2000182//regulation of progesterone biosynthetic process"	zf-C2H2
ENSG00000120742	32.36	31.261	33.444	30.073	31.583	35.245	1279	1234	964	874	1019	875	SERP1	stress associated endoplasmic reticulum protein 1 [Source:HGNC Symbol;Acc:HGNC:10759]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0006006//glucose metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0007009//plasma membrane organization;GO:0009791//post-embryonic development;GO:0010259//multicellular organism aging;GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032024//positive regulation of insulin secretion;GO:0045727//positive regulation of translation;GO:0046622//positive regulation of organ growth;GO:0048644//muscle organ morphogenesis;GO:0060124//positive regulation of growth hormone secretion	--
ENSG00000120756	13.686	11.07	13.555	8.679	9.357	11.64	963	804	689	482	587	650	PLS1	plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090]	-	-	-	-	GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0005903//brush border;GO:0032420//stereocilium;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:1990357//terminal web	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0001951//intestinal D-glucose absorption;GO:0032532//regulation of microvillus length;GO:0040018//positive regulation of multicellular organism growth;GO:0051017//actin filament bundle assembly;GO:0051639//actin filament network formation;GO:0060088//auditory receptor cell stereocilium organization;GO:0060121//vestibular receptor cell stereocilium organization;GO:1902896//terminal web assembly;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000120784	7.534	3.146	3.437	3.876	3.042	3.204	347	241	200	155	182	158	ZFP30	ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000120798	10.593	10.696	12.076	9.71	9.402	11.374	467	398	327	315	334	339	NR2C1	nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0038023//signaling receptor activity;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0043401//steroid hormone mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0048856//anatomical structure development"	RXR-like
ENSG00000120800	3.342	2.682	2.19	1.643	2.104	1.842	626	505	303	228	333	251	UTP20	UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030686//90S preribosome;GO:0030688//preribosome, small subunit precursor;GO:0032040//small-subunit processome"	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0008285//negative regulation of cell population proliferation"	--
ENSG00000120802	15.421	12.11	14.361	9.351	12.126	13.068	980	794	639	469	604	606	TMPO	thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0045296//cadherin binding	-	--
ENSG00000120805	58.15	64.303	54.205	49.27	48.556	55.582	2773	2764	1924	1625	1820	1795	ARL1	ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding	"GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0009404//toxin metabolic process;GO:0016192//vesicle-mediated transport;GO:0031584//activation of phospholipase D activity;GO:0034067//protein localization to Golgi apparatus;GO:0042147//retrograde transport, endosome to Golgi;GO:0048193//Golgi vesicle transport"	--
ENSG00000120820	1.915	2.271	1.909	2.59	2.726	2.057	76	85	56	76	88	59	GLT8D2	glycosyltransferase 8 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24890]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	-	--
ENSG00000120832	5.218	5.033	4.903	5.234	5.175	4.67	215	205	160	160	165	154	MTERF2	mitochondrial transcription termination factor 2 [Source:HGNC Symbol;Acc:HGNC:30779]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006393//termination of mitochondrial transcription"	--
ENSG00000120833	0.705	0.467	0.188	0.305	0.266	0.224	22	17	4	6	6	7	SOCS2	suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:HGNC:19382]	Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Endocrine system;Endocrine system;Endocrine system;Endocrine and metabolic disease	"ko04630//JAK-STAT signaling pathway;ko04910//Insulin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04917//Prolactin signaling pathway;ko04930//Type II diabetes mellitus"	K04695;K04695;K04695;K04695;K04695	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex	GO:0005131//growth hormone receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0001558//regulation of cell growth;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007595//lactation;GO:0009966//regulation of signal transduction;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0032355//response to estradiol;GO:0032870//cellular response to hormone stimulus;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0040014//regulation of multicellular organism growth;GO:0040015//negative regulation of multicellular organism growth;GO:0043066//negative regulation of apoptotic process;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045666//positive regulation of neuron differentiation;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0060396//growth hormone receptor signaling pathway;GO:0060749//mammary gland alveolus development	--
ENSG00000120837	12.031	9.206	10.014	9.864	9.258	12.435	545	419	342	321	352	374	NFYB	nuclear transcription factor Y subunit beta [Source:HGNC Symbol;Acc:HGNC:7805]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Infectious disease: viral;Immune system	ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04612//Antigen processing and presentation	K08065;K08065;K08065	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0140297//DNA-binding transcription factor binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035065//regulation of histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0080182//histone H3-K4 trimethylation;GO:1990830//cellular response to leukemia inhibitory factor"	NF-YB
ENSG00000120860	11.226	13.965	11.596	9.997	10.496	12.667	205	255	157	134	163	168	WASHC3	WASH complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:24256]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18463	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0031901//early endosome membrane;GO:0071203//WASH complex	GO:0005515//protein binding	GO:0006887//exocytosis;GO:0008150//biological_process;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030041//actin filament polymerization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000120868	3.433	2.784	2.924	2.169	2.582	2.121	512.8	405	322	240	324	222	APAF1	apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Infectious disease: bacterial;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04210//Apoptosis;ko05222//Small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084;K02084	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0043293//apoptosome;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0043531//ADP binding	GO:0001666//response to hypoxia;GO:0001822//kidney development;GO:0001843//neural tube closure;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007568//aging;GO:0007584//response to nutrient;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0010659//cardiac muscle cell apoptotic process;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0051402//neuron apoptotic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072432//response to G1 DNA damage checkpoint signaling;GO:0097190//apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1902510//regulation of apoptotic DNA fragmentation;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000120875	142.638	140.213	112.652	119.743	140.637	104.016	16349	16189	9538	10186	13661	8692	DUSP4	dual specificity phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:3070]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity;GO:1990439//MAP kinase serine/threonine phosphatase activity	GO:0001706//endoderm formation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000120885	2154.769	2023.008	2282.387	1940.226	1931.985	2029.354	32629	34378	26279	21161	24744	22097	CLU	clusterin [Source:HGNC Symbol;Acc:HGNC:2095]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K17252	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0009986//cell surface;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0034366//spherical high-density lipoprotein particle;GO:0042583//chromaffin granule;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0072562//blood microparticle;GO:0097418//neurofibrillary tangle;GO:0097440//apical dendrite;GO:0099020//perinuclear endoplasmic reticulum lumen	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding;GO:0048156//tau protein binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding;GO:0140597//protein carrier activity	"GO:0000902//cell morphogenesis;GO:0001774//microglial cell activation;GO:0001836//release of cytochrome c from mitochondria;GO:0002376//immune system process;GO:0002434//immune complex clearance;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0017038//protein import;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032286//central nervous system myelin maintenance;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043691//reverse cholesterol transport;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050821//protein stabilization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0051788//response to misfolded protein;GO:0060548//negative regulation of cell death;GO:0061077//chaperone-mediated protein folding;GO:0061518//microglial cell proliferation;GO:0061740//protein targeting to lysosome involved in chaperone-mediated autophagy;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:1900221//regulation of amyloid-beta clearance;GO:1901214//regulation of neuron death;GO:1901216//positive regulation of neuron death;GO:1902004//positive regulation of amyloid-beta formation;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902430//negative regulation of amyloid-beta formation;GO:1902847//regulation of neuronal signal transduction;GO:1902949//positive regulation of tau-protein kinase activity;GO:1902998//positive regulation of neurofibrillary tangle assembly;GO:1903573//negative regulation of response to endoplasmic reticulum stress;GO:1905892//negative regulation of cellular response to thapsigargin;GO:1905895//negative regulation of cellular response to tunicamycin;GO:1905907//negative regulation of amyloid fibril formation;GO:1905908//positive regulation of amyloid fibril formation;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000120889	12.745	12.541	13.618	13.076	13.629	14.971	848.5	816.75	701.44	633.65	768.82	758	TNFRSF10B	TNF receptor superfamily member 10b [Source:HGNC Symbol;Acc:HGNC:11905]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Immune system;Infectious disease: viral;Cell growth and death;Cell growth and death;Signaling molecules and interaction;Cell growth and death	ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04217//Necroptosis;ko04210//Apoptosis;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04115//p53 signaling pathway	K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722;K04722	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0036463//TRAIL receptor activity;GO:0038023//signaling receptor activity;GO:0045569//TRAIL binding	GO:0002357//defense response to tumor cell;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0034976//response to endoplasmic reticulum stress;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000120896	28.282	33.446	31.927	35.495	39.525	40.335	1005	1264	917	1090	1230	1062	SORBS3	sorbin and SH3 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30907]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0030055//cell-substrate junction	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0017166//vinculin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0031589//cell-substrate adhesion;GO:0043410//positive regulation of MAPK cascade;GO:0051495//positive regulation of cytoskeleton organization;GO:0051496//positive regulation of stress fiber assembly	--
ENSG00000120899	51.659	56.001	52.744	34.048	42.87	31.399	3465	4033	2552	1756	2452	1625	PTK2B	protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune system;Infectious disease: viral;Immune system;Endocrine system	ko04020//Calcium signaling pathway;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko05161//Hepatitis B;ko04670//Leukocyte transendothelial migration;ko04912//GnRH signaling pathway	K05871;K05871;K05871;K05871;K05871;K05871;K05871;K05871;K05871;K05871	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0097440//apical dendrite;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004972//NMDA glutamate receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0043423//3-phosphoinositide-dependent protein kinase binding;GO:0044877//protein-containing complex binding	"GO:0000165//MAPK cascade;GO:0000302//response to reactive oxygen species;GO:0001525//angiogenesis;GO:0001556//oocyte maturation;GO:0001666//response to hypoxia;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002040//sprouting angiogenesis;GO:0002250//adaptive immune response;GO:0002315//marginal zone B cell differentiation;GO:0002376//immune system process;GO:0002688//regulation of leukocyte chemotaxis;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006968//cellular defense response;GO:0006970//response to osmotic stress;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007172//signal complex assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009725//response to hormone;GO:0009749//response to glucose;GO:0010226//response to lithium ion;GO:0010243//response to organonitrogen compound;GO:0010595//positive regulation of endothelial cell migration;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0010752//regulation of cGMP-mediated signaling;GO:0010758//regulation of macrophage chemotaxis;GO:0010976//positive regulation of neuron projection development;GO:0014009//glial cell proliferation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030279//negative regulation of ossification;GO:0030307//positive regulation of cell growth;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0030838//positive regulation of actin filament polymerization;GO:0031175//neuron projection development;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032960//regulation of inositol trisphosphate biosynthetic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035902//response to immobilization stress;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042127//regulation of cell population proliferation;GO:0042220//response to cocaine;GO:0042542//response to hydrogen peroxide;GO:0042976//activation of Janus kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0043149//stress fiber assembly;GO:0043157//response to cation stress;GO:0043267//negative regulation of potassium ion transport;GO:0043507//positive regulation of JUN kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043534//blood vessel endothelial cell migration;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045453//bone resorption;GO:0045471//response to ethanol;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045727//positive regulation of translation;GO:0045765//regulation of angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048041//focal adhesion assembly;GO:0048167//regulation of synaptic plasticity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050848//regulation of calcium-mediated signaling;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0051591//response to cAMP;GO:0051592//response to calcium ion;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0065003//protein-containing complex assembly;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071300//cellular response to retinoic acid;GO:0071498//cellular response to fluid shear stress;GO:0086100//endothelin receptor signaling pathway;GO:0090630//activation of GTPase activity;GO:2000058//regulation of ubiquitin-dependent protein catabolic process;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000114//regulation of establishment of cell polarity;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000310//regulation of NMDA receptor activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000538//positive regulation of B cell chemotaxis;GO:2000573//positive regulation of DNA biosynthetic process"	--
ENSG00000120903	0	0.012	0	0	0	0	0	1	0	0	0	0	CHRNA2	cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04804	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0045171//intercellular bridge;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0050997//quaternary ammonium group binding;GO:1901363//heterocyclic compound binding	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:1905144//response to acetylcholine"	--
ENSG00000120907	0.298	0.486	0.585	0.374	0.262	0.427	17	25	22	20	13	18	ADRA1A	adrenoceptor alpha 1A [Source:HGNC Symbol;Acc:HGNC:277]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Circulatory system;Circulatory system;Signal transduction;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04152//AMPK signaling pathway;ko04970//Salivary secretion	K04135;K04135;K04135;K04135;K04135;K04135;K04135	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0098691//dopaminergic synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004937//alpha1-adrenergic receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0001985//negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure;GO:0001994//norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006915//apoptotic process;GO:0006937//regulation of muscle contraction;GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007512//adult heart development;GO:0007568//aging;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0010259//multicellular organism aging;GO:0010460//positive regulation of heart rate;GO:0010507//negative regulation of autophagy;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0019229//regulation of vasoconstriction;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035265//organ growth;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0045760//positive regulation of action potential;GO:0045907//positive regulation of vasoconstriction;GO:0045987//positive regulation of smooth muscle contraction;GO:0055117//regulation of cardiac muscle contraction;GO:0060073//micturition;GO:0060402//calcium ion transport into cytosol;GO:0060452//positive regulation of cardiac muscle contraction;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0090037//positive regulation of protein kinase C signaling;GO:0097195//pilomotor reflex;GO:0150099//neuron-glial cell signaling;GO:1903997//positive regulation of non-membrane spanning protein tyrosine kinase activity;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000120910	11.096	13.356	14.284	10.738	12.554	15.551	419	429	328	280	409	321	PPP3CC	protein phosphatase 3 catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:9316]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cell growth and death;Nervous system;Development and regeneration;Nervous system;Immune system;Immune system;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Substance dependence;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04380//Osteoclast differentiation;ko04724//Glutamatergic synapse;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04370//VEGF signaling pathway	K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005955//calcineurin complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0016787//hydrolase activity;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007420//brain development;GO:0033173//calcineurin-NFAT signaling cascade;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0097720//calcineurin-mediated signaling;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane	--
ENSG00000120913	16.57	19.454	19.052	22.086	19.175	19.059	246	290	209.98	256.76	234	215.01	PDLIM2	PDZ and LIM domain 2 [Source:HGNC Symbol;Acc:HGNC:13992]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding	GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0061061//muscle structure development	--
ENSG00000120915	18.378	19.495	24.197	23.744	22.256	17.941	613	676	571	566	653	427	EPHX2	epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko04146//Peroxisome;ko00590//Arachidonic acid metabolism	K08726;K08726;K08726;K08726;K08726	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004301//epoxide hydrolase activity;GO:0015643//toxic substance binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033885//10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0052642//lysophosphatidic acid phosphatase activity	GO:0006629//lipid metabolic process;GO:0008152//metabolic process;GO:0009636//response to toxic substance;GO:0010628//positive regulation of gene expression;GO:0016311//dephosphorylation;GO:0019439//aromatic compound catabolic process;GO:0042632//cholesterol homeostasis;GO:0046272//stilbene catabolic process;GO:0046839//phospholipid dephosphorylation;GO:0090181//regulation of cholesterol metabolic process;GO:0097176//epoxide metabolic process	--
ENSG00000120925	4.254	3.465	2.676	2.921	2.859	4.462	271	239	145	144	157	161	RNF170	ring finger protein 170 [Source:HGNC Symbol;Acc:HGNC:25358]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000120937	2.451	2.032	9.312	0.552	0.725	0.374	36	30	101	6	9	4	NPPB	natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940]	Organismal Systems;Environmental Information Processing;Organismal Systems	Environmental adaptation;Signal transduction;Circulatory system	ko04714//Thermogenesis;ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction	K12335;K12335;K12335	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008613//diuretic hormone activity;GO:0051427//hormone receptor binding	GO:0003085//negative regulation of systemic arterial blood pressure;GO:0003161//cardiac conduction system development;GO:0006182//cGMP biosynthetic process;GO:0006457//protein folding;GO:0007166//cell surface receptor signaling pathway;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007589//body fluid secretion;GO:0008217//regulation of blood pressure;GO:0016525//negative regulation of angiogenesis;GO:0019934//cGMP-mediated signaling;GO:0030308//negative regulation of cell growth;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0042311//vasodilation;GO:0043114//regulation of vascular permeability;GO:0097746//blood vessel diameter maintenance	--
ENSG00000120942	7.625	6.902	6.191	7.009	7.597	8.501	515	501	335	382	435	442	UBIAD1	UbiA prenyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30791]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031966//mitochondrial membrane	"GO:0004659//prenyltransferase activity;GO:0005515//protein binding;GO:0016209//antioxidant activity;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups"	"GO:0006744//ubiquinone biosynthetic process;GO:0009234//menaquinone biosynthetic process;GO:0032194//ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate;GO:0042371//vitamin K biosynthetic process;GO:0042373//vitamin K metabolic process;GO:0098869//cellular oxidant detoxification"	--
ENSG00000120948	75.727	70.738	75.103	70.679	73.138	72.431	3044	2977	2271	2148	2548	2223	TARDBP	TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571]	Human Diseases;Human Diseases;Genetic Information Processing	Neurodegenerative disease;Neurodegenerative disease;Translation	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko03015//mRNA surveillance pathway	K23600;K23600;K23600	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0097157//pre-mRNA intronic binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0031647//regulation of protein stability;GO:0042307//positive regulation of protein import into nucleus;GO:0042752//regulation of circadian rhythm;GO:0042981//regulation of apoptotic process;GO:0043922//negative regulation by host of viral transcription;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0071765//nuclear inner membrane organization	--
ENSG00000120949	0.02	0	0.028	0	0	0	1	0	1	0	0	0	TNFRSF8	TNF receptor superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11923]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05145	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0032759//positive regulation of TRAIL production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043065//positive regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000120952	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF2	PRAME family member 2 [Source:HGNC Symbol;Acc:HGNC:28841]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000120963	24.704	27.072	32.376	31.486	30.588	34.824	838	829	696	670	760	745	ZNF706	zinc finger protein 706 [Source:HGNC Symbol;Acc:HGNC:24992]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0046872//metal ion binding	"GO:0006417//regulation of translation;GO:0045892//negative regulation of transcription, DNA-templated;GO:1902455//negative regulation of stem cell population maintenance"	Others
ENSG00000120992	24.966	16.213	21.813	19.251	26.627	23.019	994	806	840	692	795	761	LYPLA1	lysophospholipase 1 [Source:HGNC Symbol;Acc:HGNC:6737]	Human Diseases;Metabolism	Cancer: overview;Lipid metabolism	ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism	K06128;K06128	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0002084//protein depalmitoylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0042997//negative regulation of Golgi to plasma membrane protein transport	--
ENSG00000121005	134.936	133.867	113.253	117.205	121.614	116.184	9791	9950	6031	6340	7377	5866	CRISPLD1	cysteine rich secretory protein LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18206]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0060325//face morphogenesis;GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000121022	20.102	20.557	21.17	16.093	15.681	20.349	542	557	420	314	359	400	COPS5	COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0008021//synaptic vesicle;GO:0008180//COP9 signalosome;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0003713//transcription coactivator activity;GO:0003743//translation initiation factor activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0019784//NEDD8-specific protease activity;GO:0019899//enzyme binding;GO:0035718//macrophage migration inhibitory factor binding;GO:0046872//metal ion binding;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0000338//protein deneddylation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046328//regulation of JNK cascade;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051726//regulation of cell cycle;GO:1903894//regulation of IRE1-mediated unfolded protein response;GO:1990182//exosomal secretion;GO:2000434//regulation of protein neddylation	--
ENSG00000121039	30.677	26.658	30.673	30.835	33.409	31.566	1764	1573	1299	1376	1591	1383	RDH10	retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11151;K11151	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650//NADP-retinol dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0001656//metanephros development;GO:0001701//in utero embryonic development;GO:0002138//retinoic acid biosynthetic process;GO:0006629//lipid metabolic process;GO:0007601//visual perception;GO:0008406//gonad development;GO:0009887//animal organ morphogenesis;GO:0014032//neural crest cell development;GO:0031076//embryonic camera-type eye development;GO:0035115//embryonic forelimb morphogenesis;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0043583//ear development;GO:0043584//nose development;GO:0048568//embryonic organ development;GO:0048703//embryonic viscerocranium morphogenesis;GO:0060431//primary lung bud formation;GO:0060449//bud elongation involved in lung branching;GO:1900054//positive regulation of retinoic acid biosynthetic process	--
ENSG00000121053	0.018	0	0	0	0	0.024	1	0	0	0	0	1	EPX	eosinophil peroxidase [Source:HGNC Symbol;Acc:HGNC:3423]	Human Diseases	Immune disease	ko05310//Asthma	K10788	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0002215//defense response to nematode;GO:0006952//defense response;GO:0006979//response to oxidative stress;GO:0032693//negative regulation of interleukin-10 production;GO:0032714//negative regulation of interleukin-5 production;GO:0032753//positive regulation of interleukin-4 production;GO:0042742//defense response to bacterium;GO:0042744//hydrogen peroxide catabolic process;GO:0072677//eosinophil migration;GO:0098869//cellular oxidant detoxification	--
ENSG00000121057	5.11	5.33	5.074	6.593	5.704	5.908	394	347	277	270	349	320	AKAP1	A-kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:367]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043229//intracellular organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding	GO:0006915//apoptotic process;GO:0140374//antiviral innate immune response	--
ENSG00000121058	6.626	5.882	5.973	4.621	4.875	5.811	362	323	241	187	225	231	COIL	coilin [Source:HGNC Symbol;Acc:HGNC:2184]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016604//nuclear body	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0030619//U1 snRNA binding;GO:0030620//U2 snRNA binding;GO:0042802//identical protein binding	GO:0000387//spliceosomal snRNP assembly	--
ENSG00000121060	8.606	9.535	10.225	12.239	11.853	11.351	1020	1133	871	978	1133	932	TRIM25	tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932]	Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Immune system	ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko04622//RIG-I-like receptor signaling pathway	K10652;K10652;K10652	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016604//nuclear body	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0039552//RIG-I binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0019076//viral release from host cell;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032880//regulation of protein localization;GO:0033280//response to vitamin D;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043627//response to estrogen;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000121064	25.432	28.041	27.309	25.712	25.504	29.523	1007	1105	795	755	855	836	SCPEP1	serine carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:29507]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0042573//retinoic acid metabolic process;GO:0045776//negative regulation of blood pressure;GO:0097746//blood vessel diameter maintenance	--
ENSG00000121067	23.029	23.002	20.644	17.947	20.084	16.621	1076	1044	738	630	762	609	SPOP	speckle type BTB/POZ protein [Source:HGNC Symbol;Acc:HGNC:11254]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K10523	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0030162//regulation of proteolysis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000121068	3.005	2.585	2.966	3.564	2.144	3.322	214	185	156	188	129	172	TBX2	T-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11597]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K10176	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001708//cell fate specification;GO:0001947//heart looping;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0003272//endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway;GO:0007521//muscle cell fate determination;GO:0007569//cell aging;GO:0008016//regulation of heart contraction;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0022008//neurogenesis;GO:0032526//response to retinoic acid;GO:0035050//embryonic heart tube development;GO:0035909//aorta morphogenesis;GO:0036302//atrioventricular canal development;GO:0042733//embryonic digit morphogenesis;GO:0043474//pigment metabolic process involved in pigmentation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048738//cardiac muscle tissue development;GO:0051145//smooth muscle cell differentiation;GO:0060021//roof of mouth development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060465//pharynx development;GO:0060560//developmental growth involved in morphogenesis;GO:0060596//mammary placode formation;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0072105//ureteric peristalsis;GO:0090103//cochlea morphogenesis;GO:0090398//cellular senescence;GO:0097325//melanocyte proliferation;GO:1901208//negative regulation of heart looping;GO:1901211//negative regulation of cardiac chamber formation;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1905072//cardiac jelly development;GO:1905222//atrioventricular canal morphogenesis;GO:2000773//negative regulation of cellular senescence"	T-box
ENSG00000121073	25.603	27.081	24.032	27.377	24.697	22.433	732	749	540	605	589	449	SLC35B1	solute carrier family 35 member B1 [Source:HGNC Symbol;Acc:HGNC:20798]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005459//UDP-galactose transmembrane transporter activity;GO:0005460//UDP-glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0015786//UDP-glucose transmembrane transport;GO:0055085//transmembrane transport;GO:0072334//UDP-galactose transmembrane transport	--
ENSG00000121075	0	0	0	0	0.017	0	0	0	0	0	1	0	TBX4	T-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11603]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0001525//angiogenesis;GO:0001708//cell fate specification;GO:0002009//morphogenesis of an epithelium;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0035108//limb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0048705//skeletal system morphogenesis;GO:1990401//embryonic lung development"	T-box
ENSG00000121101	0.101	0.02	0	0	0.012	0.138	10	2	0	0	1	3	TEX14	"testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737]"	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007140//male meiotic nuclear division;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0032091//negative regulation of protein binding;GO:0032466//negative regulation of cytokinesis;GO:0043063//intercellular bridge organization;GO:0051301//cell division;GO:0051306//mitotic sister chromatid separation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000121104	6.462	6.368	5.764	6.567	7.195	6.914	309	306	197	235	287	225	FAM117A	family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179]	-	-	-	-	-	-	-	--
ENSG00000121152	0.955	0.886	0.964	1.043	1.107	1.314	41	39	30	28	31	41	NCAPH	non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0007143//female meiotic nuclear division;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0045132//meiotic chromosome segregation;GO:0051301//cell division;GO:0051309//female meiosis chromosome separation;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000121207	34.288	27.421	39.604	60.51	48.275	56.404	3022	2394	2429	3691	3563	3457	LRAT	lecithin retinol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6685]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Metabolism of cofactors and vitamins;Digestive system	ko01100//Metabolic pathways;ko00830//Retinol metabolism;ko04977//Vitamin digestion and absorption	K00678;K00678;K00678	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0001972//retinoic acid binding;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016416//O-palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019841//retinol binding;GO:0047173//phosphatidylcholine-retinol O-acyltransferase activity;GO:0102279//lecithin:11-cis retinol acyltransferase activity	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006776//vitamin A metabolic process;GO:0007601//visual perception;GO:0009617//response to bacterium;GO:0032370//positive regulation of lipid transport;GO:0032526//response to retinoic acid;GO:0033189//response to vitamin A;GO:0042572//retinol metabolic process;GO:0050896//response to stimulus;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000121210	0.404	0.541	0.287	0.273	0.467	0.502	42	56	22	21	41	38	TMEM131L	transmembrane 131 like [Source:HGNC Symbol;Acc:HGNC:29146]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0016055//Wnt signaling pathway;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000121211	0.156	0	0.07	0	0.123	0	3	0	1	0	2	0	MND1	meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0007131//reciprocal meiotic recombination;GO:0051321//meiotic cell cycle	--
ENSG00000121236	2.472	2.115	1.567	1.24	1.766	1.762	111.09	128.1	68	63	95	87	TRIM6	tripartite motif containing 6 [Source:HGNC Symbol;Acc:HGNC:16277]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0140297//DNA-binding transcription factor binding;GO:1990782//protein tyrosine kinase binding	"GO:0000209//protein polyubiquitination;GO:0002230//positive regulation of defense response to virus by host;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0032496//response to lipopolysaccharide;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035458//cellular response to interferon-beta;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0098586//cellular response to virus;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2000737//negative regulation of stem cell differentiation"	--
ENSG00000121270	0.585	0.588	0.406	0.585	0.378	0.348	45	57	32	43	35	24	ABCC11	ATP binding cassette subfamily C member 11 [Source:HGNC Symbol;Acc:HGNC:14639]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05671	GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008514//organic anion transmembrane transporter activity;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015216//purine nucleotide transmembrane transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0015432//ABC-type bile acid transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0015698//inorganic anion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0015865//purine nucleotide transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0071716//leukotriene transport	--
ENSG00000121274	2.155	1.857	1.953	1.358	1.464	1.559	372	326	248	174	216	194	TENT4B	terminal nucleotidyltransferase 4B [Source:HGNC Symbol;Acc:HGNC:30758]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K03514	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031499//TRAMP complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding;GO:0070034//telomerase RNA binding;GO:0070568//guanylyltransferase activity	GO:0006364//rRNA processing;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0010587//miRNA catabolic process;GO:0016070//RNA metabolic process;GO:0031123//RNA 3'-end processing;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0033500//carbohydrate homeostasis;GO:0043629//ncRNA polyadenylation;GO:0043630//ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process;GO:0043631//RNA polyadenylation;GO:0051301//cell division;GO:0060212//negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0071044//histone mRNA catabolic process;GO:0071050//sno(s)RNA polyadenylation;GO:0071076//RNA 3' uridylation;GO:0071897//DNA biosynthetic process;GO:1905870//positive regulation of 3'-UTR-mediated mRNA stabilization	--
ENSG00000121281	5.304	5.218	3.883	2.64	4.77	3.042	446.25	471.15	197.7	159.55	233.95	176.89	ADCY7	adenylate cyclase 7 [Source:HGNC Symbol;Acc:HGNC:238]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis"	K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047;K08047	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding	GO:0002819//regulation of adaptive immune response;GO:0006171//cAMP biosynthetic process;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0060135//maternal process involved in female pregnancy;GO:0071285//cellular response to lithium ion;GO:0071361//cellular response to ethanol;GO:1900016//negative regulation of cytokine production involved in inflammatory response	--
ENSG00000121289	5.691	6.918	4.379	4.461	4.112	4.457	397	413	238	222	224	188	CEP89	centrosomal protein 89 [Source:HGNC Symbol;Acc:HGNC:25907]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0031514//motile cilium;GO:0045202//synapse;GO:0097539//ciliary transition fiber;GO:0097730//non-motile cilium	GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0007268//chemical synaptic transmission;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000121297	2.646	2.604	2.462	2.069	2.76	2.473	278	275	191	161	245	189	TSHZ3	teashirt zinc finger homeobox 3 [Source:HGNC Symbol;Acc:HGNC:30700]	Environmental Information Processing	Signal transduction	ko04391//Hippo signaling pathway - fly	K09236	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0030426//growth cone;GO:0042995//cell projection	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060291//long-term synaptic potentiation"	zf-C2H2
ENSG00000121310	18.238	18.694	18.038	19.51	20.582	18.988	486	497	363	387	472	366	ECHDC2	enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408]	-	-	-	-	GO:0005739//mitochondrion	GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity;GO:0016829//lyase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000121314	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R8	taste 2 receptor member 8 [Source:HGNC Symbol;Acc:HGNC:14915]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000121316	28.336	27.188	30.857	30.883	32.933	37.107	1152	1111	908	930	1108	1089	PLBD1	phospholipase B domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26215]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005829//cytosol	GO:0004620//phospholipase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process	--
ENSG00000121318	0	0	0	0	0	0.064	0	0	0	0	0	1	TAS2R10	taste 2 receptor member 10 [Source:HGNC Symbol;Acc:HGNC:14918]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000121335	0	0	0	0	0	0	0	0	0	0	0	0	PRB2	proline rich protein BstNI subfamily 2 [Source:HGNC Symbol;Acc:HGNC:9338]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13911	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000121350	2.33	2.091	2.049	2.012	2.286	2.023	186.37	162.06	127.94	109.97	127.52	119.39	PYROXD1	pyridine nucleotide-disulphide oxidoreductase domain 1 [Source:HGNC Symbol;Acc:HGNC:26162]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030017//sarcomere	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0034599//cellular response to oxidative stress	--
ENSG00000121351	0	0	0	0	0	0	0	0	0	0	0	0	IAPP	islet amyloid polypeptide [Source:HGNC Symbol;Acc:HGNC:5329]	Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Endocrine and metabolic disease	ko04080//Neuroactive ligand-receptor interaction;ko04950//Maturity onset diabetes of the young	K08039;K08039	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0010739//positive regulation of protein kinase A signaling;GO:0010823//negative regulation of mitochondrion organization;GO:0019233//sensory perception of pain;GO:0031333//negative regulation of protein-containing complex assembly;GO:0042755//eating behavior;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045596//negative regulation of cell differentiation;GO:0045779//negative regulation of bone resorption;GO:0051897//positive regulation of protein kinase B signaling;GO:0097647//amylin receptor signaling pathway;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000121361	13.42	13.293	13.281	10.733	11.181	13.211	633	631	463	375	446	454	KCNJ8	potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269]	Environmental Information Processing	Signal transduction	ko04022//cGMP-PKG signaling pathway	K05001	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0008282//inward rectifying potassium channel;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030016//myofibril;GO:0031004//potassium ion-transporting ATPase complex;GO:0042383//sarcolemma;GO:0043231//intracellular membrane-bounded organelle	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0017098//sulfonylurea receptor binding;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0001822//kidney development;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007507//heart development;GO:0032496//response to lipopolysaccharide;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0150104//transport across blood-brain barrier;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000121377	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R7	taste 2 receptor member 7 [Source:HGNC Symbol;Acc:HGNC:14913]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000121380	0	0	0	0	0	0	0	0	0	0	0	0	BCL2L14	BCL2 like 14 [Source:HGNC Symbol;Acc:HGNC:16657]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043229//intracellular organelle	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000121381	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R9	taste 2 receptor member 9 [Source:HGNC Symbol;Acc:HGNC:14917]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000121390	14.966	13.259	14.147	12.838	11.008	12.034	587	549	431	373	397	379	PSPC1	paraspeckle component 1 [Source:HGNC Symbol;Acc:HGNC:20320]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0042382//paraspeckles	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0042752//regulation of circadian rhythm;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000121406	3.306	2.99	2.152	2.188	2.299	2.373	265	256	135	138	164	146	ZNF549	zinc finger protein 549 [Source:HGNC Symbol;Acc:HGNC:26632]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000121410	0.47	0.596	0.888	0.404	0.456	0.431	33	42	46	21	27	22	A1BG	alpha-1-B glycoprotein [Source:HGNC Symbol;Acc:HGNC:5]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0110165//cellular anatomical entity;GO:1904813//ficolin-1-rich granule lumen	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000121413	27.396	28.053	28.312	23.944	26.948	26.175	1239.05	1304.95	923.1	791.46	1021.33	885.24	ZSCAN18	zinc finger and SCAN domain containing 18 [Source:HGNC Symbol;Acc:HGNC:21037]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000121417	6.028	5.558	6.14	5.107	6.096	6.342	353	300	257	220	292	268	ZNF211	zinc finger protein 211 [Source:HGNC Symbol;Acc:HGNC:13003]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000121440	18.988	17.473	14.832	11.803	12.737	11.646	1554	1425	918	711	879	730	PDZRN3	PDZ domain containing ring finger 3 [Source:HGNC Symbol;Acc:HGNC:17704]	-	-	-	-	GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0045202//synapse	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007528//neuromuscular junction development;GO:0016567//protein ubiquitination	--
ENSG00000121446	0	0	0	0	0	0	0	0	0	0	0	0	RGSL1	regulator of G protein signaling like 1 [Source:HGNC Symbol;Acc:HGNC:18636]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000121454	0.163	0.167	0.164	0.535	0.243	0.254	19.81	20.39	14.71	11.7	24.89	22.37	LHX4	LIM homeobox 4 [Source:HGNC Symbol;Acc:HGNC:21734]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0021526//medial motor column neuron differentiation;GO:0030182//neuron differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000121481	8.035	6.591	6.721	7.361	7.15	5.275	342	302	254	233	261	211	RNF2	ring finger protein 2 [Source:HGNC Symbol;Acc:HGNC:10061]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0001739//sex chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex;GO:0071339//MLL1 complex	GO:0003682//chromatin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0071535//RING-like zinc finger domain binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0001702//gastrulation with mouth forming second;GO:0007281//germ cell development;GO:0009948//anterior/posterior axis specification;GO:0010467//gene expression;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0035518//histone H2A monoubiquitination;GO:0036353//histone H2A-K119 monoubiquitination;GO:0043433//negative regulation of DNA-binding transcription factor activity	--
ENSG00000121486	4.845	3.882	4.079	3.552	4.24	3.92	428	353	271	238	324	258	TRMT1L	tRNA methyltransferase 1 like [Source:HGNC Symbol;Acc:HGNC:16782]	-	-	-	-	GO:0005634//nucleus	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0002940//tRNA N2-guanine methylation;GO:0007610//behavior;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000121542	5.982	5.344	5.183	3.963	3.928	4.771	225	229	158	126	188	178	SEC22A	"SEC22 homolog A, vesicle trafficking protein [Source:HGNC Symbol;Acc:HGNC:20260]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005215//transporter activity;GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000121552	0.065	0	0	0	0	0	1	0	0	0	0	0	CSTA	cystatin A [Source:HGNC Symbol;Acc:HGNC:2481]	-	-	-	-	GO:0001533//cornified envelope;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1904090//peptidase inhibitor complex	GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0007155//cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0045861//negative regulation of proteolysis;GO:0098609//cell-cell adhesion	--
ENSG00000121570	0	0	0	0	0	0	0	0	0	0	0	0	DPPA4	developmental pluripotency associated 4 [Source:HGNC Symbol;Acc:HGNC:19200]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0048731//system development;GO:0060484//lung-associated mesenchyme development	--
ENSG00000121577	0.767	0.636	0.704	0.637	0.44	2.79	28	24	19	18	14	15	POPDC2	popeye domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17648]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0003674//molecular_function;GO:0030552//cAMP binding	GO:0002027//regulation of heart rate;GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0008150//biological_process;GO:0042391//regulation of membrane potential;GO:0051146//striated muscle cell differentiation	--
ENSG00000121578	15.128	14.296	11.354	12.687	12.223	13.97	631	598	379	373	494	440	B4GALT4	"beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K07969;K07969;K07969	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment;GO:0032580//Golgi cisterna membrane;GO:0098588//bounding membrane of organelle;GO:0098791//Golgi apparatus subcompartment	GO:0003945//N-acetyllactosamine synthase activity;GO:0005515//protein binding;GO:0008378//galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035250//UDP-galactosyltransferase activity;GO:0046872//metal ion binding	GO:0001572//lactosylceramide biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0070085//glycosylation;GO:1901137//carbohydrate derivative biosynthetic process	--
ENSG00000121579	45.092	31.197	31.507	31.972	33.852	36.388	2265	1791	1427	1245	1478	1282	NAA50	"N-alpha-acetyltransferase 50, NatE catalytic subunit [Source:HGNC Symbol;Acc:HGNC:29533]"	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031415//NatA complex;GO:0070062//extracellular exosome	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0052858//peptidyl-lysine acetyltransferase activity	"GO:0006474//N-terminal protein amino acid acetylation;GO:0007064//mitotic sister chromatid cohesion;GO:0016573//histone acetylation;GO:0034087//establishment of mitotic sister chromatid cohesion;GO:0043967//histone H4 acetylation;GO:0071962//mitotic sister chromatid cohesion, centromeric"	--
ENSG00000121594	0	0.37	0	0.087	0	0.12	0	8	0	2	0	4	CD80	CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Immune disease;Immune disease;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune system;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05322//Systemic lupus erythematosus;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko04620//Toll-like receptor signaling pathway;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K05412;K05412;K05412;K05412;K05412;K05412;K05412;K05412;K05412;K05412	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098636//protein complex involved in cell adhesion	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity	"GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0031295//T cell costimulation;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032743//positive regulation of interleukin-2 production;GO:0035556//intracellular signal transduction;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071222//cellular response to lipopolysaccharide"	--
ENSG00000121621	0.593	0.351	0.42	0.381	0.418	0.465	42	25	22	20	25	24	KIF18A	kinesin family member 18A [Source:HGNC Symbol;Acc:HGNC:29441]	-	-	-	-	GO:0000776//kinetochore;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005901//caveola;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection;GO:0061673//mitotic spindle astral microtubule;GO:1990023//mitotic spindle midzone	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0051010//microtubule plus-end binding;GO:0070463//tubulin-dependent ATPase activity	GO:0000070//mitotic sister chromatid segregation;GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0007080//mitotic metaphase plate congression;GO:0007140//male meiotic nuclear division;GO:0015031//protein transport;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071392//cellular response to estradiol stimulus;GO:0072520//seminiferous tubule development	--
ENSG00000121634	0	0	0	0	0	0	0	0	0	0	0	0	GJA8	gap junction protein alpha 8 [Source:HGNC Symbol;Acc:HGNC:4281]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002088//lens development in camera-type eye;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0032645//regulation of granulocyte macrophage colony-stimulating factor production;GO:0043010//camera-type eye development;GO:0055085//transmembrane transport;GO:1902551//regulation of catalase activity;GO:1903282//regulation of glutathione peroxidase activity;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000121644	27.459	24.79	21.364	18.385	21.291	24.298	2145	2038	1219	1082	1333	1288	DESI2	desumoylating isopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:24264]	-	-	-	-	GO:0005737//cytoplasm	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0101005//deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0070646//protein modification by small protein removal;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000121653	17.957	17.365	19.99	21.321	20.843	20.489	1136	1106	934	1000	1114	944	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6882]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04434	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031966//mitochondrial membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044302//dentate gyrus mossy fiber;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0007258//JUN phosphorylation;GO:0016192//vesicle-mediated transport;GO:0043508//negative regulation of JUN kinase activity;GO:0046328//regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000121671	13.507	13.878	14.885	13.916	14.229	12.241	1161	1198	942	886	1031	765	CRY2	cryptochrome circadian regulator 2 [Source:HGNC Symbol;Acc:HGNC:2385]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K02295	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0009881//photoreceptor activity;GO:0009882//blue light photoreceptor activity;GO:0016829//lyase activity;GO:0016922//nuclear receptor binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0071949//FAD binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009785//blue light signaling pathway;GO:0014823//response to activity;GO:0018298//protein-chromophore linkage;GO:0019915//lipid storage;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0042593//glucose homeostasis;GO:0042752//regulation of circadian rhythm;GO:0042754//negative regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050896//response to stimulus;GO:2000118//regulation of sodium-dependent phosphate transport;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:2000850//negative regulation of glucocorticoid secretion"	--
ENSG00000121680	6.652	5.216	8.226	8.234	7.251	7.582	207	170	193	190	192	163	PEX16	peroxisomal biogenesis factor 16 [Source:HGNC Symbol;Acc:HGNC:8857]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13335	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0016558//protein import into peroxisome matrix;GO:0022615//protein to membrane docking;GO:0032581//ER-dependent peroxisome organization;GO:0045046//protein import into peroxisome membrane;GO:0106101//ER-dependent peroxisome localization	--
ENSG00000121690	1.578	1.763	1.762	1.794	1.77	1.637	57	64	47	48	54	43	DEPDC7	DEP domain containing 7 [Source:HGNC Symbol;Acc:HGNC:29899]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0035556//intracellular signal transduction	--
ENSG00000121691	38.581	35.068	45.069	44.773	48.795	52.551	1831	1675	1579	1576	1959	1817	CAT	catalase [Source:HGNC Symbol;Acc:HGNC:1516]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Signal transduction;Global and overview maps;Aging;Transport and catabolism;Aging;Amino acid metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04068//FoxO signaling pathway;ko01200//Carbon metabolism;ko04211//Longevity regulating pathway;ko04146//Peroxisome;ko04213//Longevity regulating pathway - multiple species;ko00380//Tryptophan metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K03781;K03781;K03781;K03781;K03781;K03781;K03781;K03781;K03781;K03781;K03781	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005764//lysosome;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062151//catalase complex;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0000268//peroxisome targeting sequence binding;GO:0004046//aminoacylase activity;GO:0004096//catalase activity;GO:0004601//peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050661//NADP binding"	GO:0000302//response to reactive oxygen species;GO:0001649//osteoblast differentiation;GO:0001657//ureteric bud development;GO:0001666//response to hypoxia;GO:0001822//kidney development;GO:0006641//triglyceride metabolic process;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0008203//cholesterol metabolic process;GO:0009060//aerobic respiration;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0009636//response to toxic substance;GO:0009642//response to light intensity;GO:0009650//UV protection;GO:0010193//response to ozone;GO:0010288//response to lead ion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0014854//response to inactivity;GO:0020027//hemoglobin metabolic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032355//response to estradiol;GO:0032868//response to insulin;GO:0033189//response to vitamin A;GO:0033197//response to vitamin E;GO:0033591//response to L-ascorbic acid;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045471//response to ethanol;GO:0046686//response to cadmium ion;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051781//positive regulation of cell division;GO:0055093//response to hyperoxia;GO:0061692//cellular detoxification of hydrogen peroxide;GO:0070542//response to fatty acid;GO:0071363//cellular response to growth factor stimulus;GO:0080184//response to phenylpropanoid;GO:0098869//cellular oxidant detoxification	--
ENSG00000121716	4.193	4.386	5.403	5.474	6.359	5.635	142	152	147	145	176	134	PILRB	paired immunoglobin like type 2 receptor beta [Source:HGNC Symbol;Acc:HGNC:18297]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K15411	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042288//MHC class I protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity	--
ENSG00000121741	22.312	16.314	17.062	11.197	13.38	15.772	2142	1582	1141	896	1113	1121	ZMYM2	zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016605//PML body	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding	GO:0008150//biological_process	--
ENSG00000121742	0	0	0	0	0.028	0.049	0	0	0	0	1	1	GJB6	gap junction protein beta 6 [Source:HGNC Symbol;Acc:HGNC:4288]	-	-	-	-	GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0048487//beta-tubulin binding;GO:0051015//actin filament binding;GO:1903763//gap junction channel activity involved in cell communication by electrical coupling	GO:0003163//sinoatrial node development;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007568//aging;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell population proliferation;GO:0010644//cell communication by electrical coupling;GO:0016264//gap junction assembly;GO:0032496//response to lipopolysaccharide;GO:0035633//maintenance of blood-brain barrier;GO:0042471//ear morphogenesis;GO:0048839//inner ear development;GO:0051602//response to electrical stimulus;GO:0055085//transmembrane transport;GO:0071333//cellular response to glucose stimulus;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000121743	0.129	0.046	0.038	0.112	0.099	0.076	14	5	3	9	9	6	GJA3	gap junction protein alpha 3 [Source:HGNC Symbol;Acc:HGNC:4277]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0055077//gap junction hemi-channel activity	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007601//visual perception;GO:0055085//transmembrane transport;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000121749	15.191	11.398	8.88	7.807	8.591	9.641	818.13	726.42	432.1	359.21	432.51	429.9	TBC1D15	TBC1 domain family member 15 [Source:HGNC Symbol;Acc:HGNC:25694]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K20168	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0043087//regulation of GTPase activity;GO:0090630//activation of GTPase activity	--
ENSG00000121753	8.759	9.488	8.578	7.521	8.497	8.8	904	979	669	555	753	569	ADGRB2	adhesion G protein-coupled receptor B2 [Source:HGNC Symbol;Acc:HGNC:944]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007422//peripheral nervous system development;GO:0016525//negative regulation of angiogenesis;GO:0033173//calcineurin-NFAT signaling cascade	--
ENSG00000121764	0	0	0	0	0	0.029	0	0	0	0	0	1	HCRTR1	hypocretin receptor 1 [Source:HGNC Symbol;Acc:HGNC:4848]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04238	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0016499//orexin receptor activity;GO:0017046//peptide hormone binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007631//feeding behavior;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000121766	17.113	17.603	16.501	14.98	14.901	14.184	558	579	399	360	412	337	ZCCHC17	zinc finger CCHC-type containing 17 [Source:HGNC Symbol;Acc:HGNC:30246]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0022625//cytosolic large ribosomal subunit	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0043489//RNA stabilization	--
ENSG00000121769	11.822	11.324	11.353	18.393	14.201	16.671	269	259	189	310	273	276	FABP3	fatty acid binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3557]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K08752	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0036041//long-chain fatty acid binding;GO:0070538//oleic acid binding	GO:0008285//negative regulation of cell population proliferation;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0032365//intracellular lipid transport;GO:0042632//cholesterol homeostasis;GO:0046320//regulation of fatty acid oxidation;GO:0050873//brown fat cell differentiation;GO:0055091//phospholipid homeostasis;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0140214//positive regulation of long-chain fatty acid import into cell;GO:2001245//regulation of phosphatidylcholine biosynthetic process	--
ENSG00000121774	53.992	49.299	51.589	48.816	48.529	48.488	2881	2751	2109	1923	2219	1923	KHDRBS1	"KH RNA binding domain containing, signal transduction associated 1 [Source:HGNC Symbol;Acc:HGNC:18116]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070618//Grb2-Sos complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding;GO:0017124//SH3 domain binding;GO:0019904//protein domain specific binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:1990782//protein tyrosine kinase binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045948//positive regulation of translational initiation;GO:0046831//regulation of RNA export from nucleus;GO:0046833//positive regulation of RNA export from nucleus;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0050852//T cell receptor signaling pathway"	--
ENSG00000121775	2.902	3.078	2.386	3.328	2.985	4.007	100	111	65	78	90	96	TMEM39B	transmembrane protein 39B [Source:HGNC Symbol;Acc:HGNC:25510]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0008150//biological_process	--
ENSG00000121797	0	0	0	0	0	0	0	0	0	0	0	0	CCRL2	C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0042379//chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000121807	0	0	0	0	0	0	0	0	0	0	0	0	CCR2	C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04177;K04177;K04177	GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019955//cytokine binding;GO:0019957//C-C chemokine binding;GO:0031727//CCR2 chemokine receptor binding;GO:0035715//chemokine (C-C motif) ligand 2 binding;GO:0035716//chemokine (C-C motif) ligand 12 binding;GO:0035717//chemokine (C-C motif) ligand 7 binding;GO:0042802//identical protein binding	"GO:0001974//blood vessel remodeling;GO:0002407//dendritic cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0002724//regulation of T cell cytokine production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0002829//negative regulation of type 2 immune response;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009611//response to wounding;GO:0010574//regulation of vascular endothelial growth factor production;GO:0010820//positive regulation of T cell chemotaxis;GO:0016525//negative regulation of angiogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0019233//sensory perception of pain;GO:0019722//calcium-mediated signaling;GO:0019725//cellular homeostasis;GO:0030097//hemopoiesis;GO:0030334//regulation of cell migration;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035696//monocyte extravasation;GO:0035705//T-helper 17 cell chemotaxis;GO:0043310//negative regulation of eosinophil degranulation;GO:0045580//regulation of T cell differentiation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0048873//homeostasis of number of cells within a tissue;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050870//positive regulation of T cell activation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060326//cell chemotaxis;GO:0061756//leukocyte adhesion to vascular endothelial cell;GO:0070098//chemokine-mediated signaling pathway;GO:0090026//positive regulation of monocyte chemotaxis;GO:0090265//positive regulation of immune complex clearance by monocytes and macrophages;GO:0090594//inflammatory response to wounding;GO:0097350//neutrophil clearance;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:1905517//macrophage migration;GO:2000412//positive regulation of thymocyte migration;GO:2000439//positive regulation of monocyte extravasation;GO:2000451//positive regulation of CD8-positive, alpha-beta T cell extravasation;GO:2000464//positive regulation of astrocyte chemotaxis;GO:2000473//positive regulation of hematopoietic stem cell migration"	--
ENSG00000121851	14.105	14.319	12.959	13.15	13.525	11.447	332	338	228	233	270	196	POLR3GL	RNA polymerase III subunit GL [Source:HGNC Symbol;Acc:HGNC:28466]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03024;K03024	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III	--
ENSG00000121853	0	0	0	0	0	0	0	0	0	0	0	0	GHSR	growth hormone secretagogue receptor [Source:HGNC Symbol;Acc:HGNC:4267]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K04284;K04284;K04284	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099699//integral component of synaptic membrane	GO:0001616//growth hormone secretagogue receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0016520//growth hormone-releasing hormone receptor activity;GO:0017046//peptide hormone binding;GO:0042562//hormone binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007565//female pregnancy;GO:0007611//learning or memory;GO:0008154//actin polymerization or depolymerization;GO:0008343//adult feeding behavior;GO:0009725//response to hormone;GO:0009755//hormone-mediated signaling pathway;GO:0010700//negative regulation of norepinephrine secretion;GO:0030252//growth hormone secretion;GO:0032094//response to food;GO:0032099//negative regulation of appetite;GO:0032100//positive regulation of appetite;GO:0032354//response to follicle-stimulating hormone;GO:0032355//response to estradiol;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032869//cellular response to insulin stimulus;GO:0036321//ghrelin secretion;GO:0040018//positive regulation of multicellular organism growth;GO:0043134//regulation of hindgut contraction;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045923//positive regulation of fatty acid metabolic process;GO:0045927//positive regulation of growth;GO:0046676//negative regulation of insulin secretion;GO:0046697//decidualization;GO:0050728//negative regulation of inflammatory response;GO:0051963//regulation of synapse assembly;GO:0051969//regulation of transmission of nerve impulse;GO:0060123//regulation of growth hormone secretion;GO:0060259//regulation of feeding behavior;GO:0060416//response to growth hormone;GO:0071222//cellular response to lipopolysaccharide;GO:0071548//response to dexamethasone;GO:0090327//negative regulation of locomotion involved in locomotory behavior;GO:0097067//cellular response to thyroid hormone stimulus;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:0099175//regulation of postsynapse organization;GO:0120058//positive regulation of small intestinal transit;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904000//positive regulation of eating behavior;GO:1904008//response to monosodium glutamate;GO:1904349//positive regulation of small intestine smooth muscle contraction;GO:1905333//regulation of gastric motility;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:2000110//negative regulation of macrophage apoptotic process	--
ENSG00000121858	0.257	0.33	0.242	0.184	0.639	0.082	10	12	6	5	21	2	TNFSF10	TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Immune system;Infectious disease: viral;Cell growth and death;Cell growth and death;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04217//Necroptosis;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04721;K04721;K04721;K04721;K04721;K04721;K04721;K04721;K04721;K04721	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0042802//identical protein binding;GO:0045569//TRAIL binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000121864	15.191	13.002	13.297	12.009	12.13	13.366	520	415	343	288	329	325	ZNF639	zinc finger protein 639 [Source:HGNC Symbol;Acc:HGNC:30950]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0030307//positive regulation of cell growth;GO:0043922//negative regulation by host of viral transcription;GO:0043923//positive regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046718//viral entry into host cell"	zf-C2H2
ENSG00000121871	0.088	0.663	0.164	0.193	0.171	0.148	8	22	11	13	14	11	SLITRK3	SLIT and NTRK like family member 3 [Source:HGNC Symbol;Acc:HGNC:23501]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane	GO:0005515//protein binding	"GO:0007409//axonogenesis;GO:0051932//synaptic transmission, GABAergic;GO:0051965//positive regulation of synapse assembly;GO:0072553//terminal button organization;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0097107//postsynaptic density assembly;GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly"	--
ENSG00000121879	5.47	3.887	4.866	2.938	4.466	4.582	680	474.95	409.46	229.26	351.54	371.55	PIK3CA	"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975]"	Metabolism;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Carbohydrate metabolism;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko01100//Metabolic pathways;ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko00562//Inositol phosphate metabolism;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm"	"GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0030295//protein kinase activator activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0043560//insulin receptor substrate binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0106310//protein serine kinase activity"	GO:0001525//angiogenesis;GO:0001889//liver development;GO:0001932//regulation of protein phosphorylation;GO:0001944//vasculature development;GO:0006006//glucose metabolic process;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006909//phagocytosis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010468//regulation of gene expression;GO:0010592//positive regulation of lamellipodium assembly;GO:0010629//negative regulation of gene expression;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0014870//response to muscle inactivity;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0030168//platelet activation;GO:0030835//negative regulation of actin filament depolymerization;GO:0031295//T cell costimulation;GO:0032008//positive regulation of TOR signaling;GO:0032147//activation of protein kinase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035994//response to muscle stretch;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0043201//response to leucine;GO:0043276//anoikis;GO:0043457//regulation of cellular respiration;GO:0043491//protein kinase B signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0043542//endothelial cell migration;GO:0044029//hypomethylation of CpG island;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0055119//relaxation of cardiac muscle;GO:0060048//cardiac muscle contraction;GO:0060612//adipose tissue development;GO:0071333//cellular response to glucose stimulus;GO:0071464//cellular response to hydrostatic pressure;GO:0071548//response to dexamethasone;GO:0086003//cardiac muscle cell contraction;GO:0097009//energy homeostasis;GO:0110053//regulation of actin filament organization;GO:1903544//response to butyrate;GO:2000270//negative regulation of fibroblast apoptotic process;GO:2000653//regulation of genetic imprinting;GO:2000811//negative regulation of anoikis	--
ENSG00000121892	13.259	10.063	9.227	6.596	7.493	8.875	1898	1469	980	700	871	924	PDS5A	PDS5 cohesin associated factor A [Source:HGNC Symbol;Acc:HGNC:29088]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0005886//plasma membrane"	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0008156//negative regulation of DNA replication;GO:0051301//cell division	--
ENSG00000121895	0	0	0	0	0	0	0	0	0	0	0	0	TMEM156	transmembrane protein 156 [Source:HGNC Symbol;Acc:HGNC:26260]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000121897	3.865	3.326	3.049	4.137	3.378	4.383	117	111	67	94	84	103	LIAS	lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00785//Lipoic acid metabolism	K03644;K03644	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0016783//sulfurtransferase activity;GO:0016992//lipoate synthase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0102552//lipoyl synthase activity (acting on glycine-cleavage complex H protein;GO:0102553//lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"	GO:0001843//neural tube closure;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0009107//lipoate biosynthetic process;GO:0009249//protein lipoylation;GO:0032496//response to lipopolysaccharide	--
ENSG00000121898	113.401	124.972	109.725	100.326	104.877	103.779	8191	9000	5800	5356	6378	5411	CPXM2	"carboxypeptidase X, M14 family member 2 [Source:HGNC Symbol;Acc:HGNC:26977]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0016485//protein processing	--
ENSG00000121900	4.072	4.377	2.915	3.412	5.152	3.088	87	94	46	54	93	48	TMEM54	transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000121903	2.175	1.875	2.344	1.716	1.762	1.984	295	295	244	200	223	242	ZSCAN20	zinc finger and SCAN domain containing 20 [Source:HGNC Symbol;Acc:HGNC:13093]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000121904	0.088	0.129	0.158	0.105	0.075	0.091	25	36	33	22	18	18	CSMD2	CUB and Sushi multiple domains 2 [Source:HGNC Symbol;Acc:HGNC:19290]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000121905	0.034	0.136	0.185	0	0.162	0.094	1	4	4	0	4	2	HPCA	hippocalcin [Source:HGNC Symbol;Acc:HGNC:5144]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030424//axon;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0032839//dendrite cytoplasm;GO:0043204//perikaryon;GO:0044327//dendritic spine head;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007420//brain development;GO:0010518//positive regulation of phospholipase activity;GO:0014070//response to organic cyclic compound;GO:0019722//calcium-mediated signaling;GO:0031283//negative regulation of guanylate cyclase activity;GO:0031584//activation of phospholipase D activity;GO:0045762//positive regulation of adenylate cyclase activity;GO:0048839//inner ear development;GO:0060041//retina development in camera-type eye;GO:0071257//cellular response to electrical stimulus;GO:0071277//cellular response to calcium ion;GO:0090314//positive regulation of protein targeting to membrane;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1901986//response to ketamine;GO:1902065//response to L-glutamate;GO:1904009//cellular response to monosodium glutamate;GO:1904010//response to Aroclor 1254	--
ENSG00000121931	4.54	3.667	3.543	3.461	3.762	3.903	254	204	134	130	174	151	LRIF1	ligand dependent nuclear receptor interacting factor 1 [Source:HGNC Symbol;Acc:HGNC:30299]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0001740//Barr body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016363//nuclear matrix;GO:0034451//centriolar satellite"	GO:0005515//protein binding;GO:0042974//retinoic acid receptor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0009048//dosage compensation by inactivation of X chromosome"	--
ENSG00000121933	0	0	0	0	0	0	0	0	0	0	0	0	TMIGD3	transmembrane and immunoglobulin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:51375]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0008285//negative regulation of cell population proliferation;GO:0009611//response to wounding;GO:0030336//negative regulation of cell migration;GO:0032088//negative regulation of NF-kappaB transcription factor activity	--
ENSG00000121940	16.113	14.664	16.575	15.302	14.874	16.713	1024.05	966.44	755.17	696.02	806.32	786.3	CLCC1	chloride channel CLIC like 1 [Source:HGNC Symbol;Acc:HGNC:29675]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0034707//chloride channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006821//chloride transport	--
ENSG00000121957	1.927	1.011	1.827	0.797	1.172	1.201	210.95	120.56	100.83	62.98	81.68	57.7	GPSM2	G protein signaling modulator 2 [Source:HGNC Symbol;Acc:HGNC:29501]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0032991//protein-containing complex;GO:0097431//mitotic spindle pole;GO:0097575//lateral cell cortex;GO:0099738//cell cortex region	GO:0000166//nucleotide binding;GO:0001965//G-protein alpha-subunit binding;GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0030695//GTPase regulator activity;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0070840//dynein complex binding	GO:0000132//establishment of mitotic spindle orientation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007186//G protein-coupled receptor signaling pathway;GO:0031291//Ran protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051661//maintenance of centrosome location;GO:0060236//regulation of mitotic spindle organization;GO:1904778//positive regulation of protein localization to cell cortex;GO:1905832//positive regulation of spindle assembly	--
ENSG00000121964	7.217	8.533	7.125	5.512	6.186	6.158	399	409.32	258	204.03	239	227	GTDC1	glycosyltransferase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20887]	-	-	-	-	-	GO:0016757//glycosyltransferase activity	-	--
ENSG00000121966	26.352	25.257	18.643	5.565	10.058	8.302	912	881	477	144	294	209	CXCR4	C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Cell motility;Infectious disease: viral;Immune system;Development and regeneration;Immune system;Immune system;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04672//Intestinal immune network for IgA production;ko04670//Leukocyte transendothelial migration;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04189;K04189;K04189;K04189;K04189;K04189;K04189;K04189;K04189;K04189;K04189;K04189	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0003779//actin binding;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019955//cytokine binding;GO:0019957//C-C chemokine binding;GO:0031625//ubiquitin protein ligase binding;GO:0032027//myosin light chain binding;GO:0036094//small molecule binding;GO:0038147//C-X-C motif chemokine 12 receptor activity;GO:0043130//ubiquitin binding	GO:0001666//response to hypoxia;GO:0001764//neuron migration;GO:0002064//epithelial cell development;GO:0002407//dendritic cell chemotaxis;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007420//brain development;GO:0008038//neuron recognition;GO:0009615//response to virus;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0016477//cell migration;GO:0019722//calcium-mediated signaling;GO:0022008//neurogenesis;GO:0022029//telencephalon cell migration;GO:0030155//regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0035470//positive regulation of vascular wound healing;GO:0038160//CXCL12-activated CXCR4 signaling pathway;GO:0043067//regulation of programmed cell death;GO:0043217//myelin maintenance;GO:0043278//response to morphine;GO:0045446//endothelial cell differentiation;GO:0046718//viral entry into host cell;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050769//positive regulation of neurogenesis;GO:0050792//regulation of viral process;GO:0050920//regulation of chemotaxis;GO:0050921//positive regulation of chemotaxis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051924//regulation of calcium ion transport;GO:0060048//cardiac muscle contraction;GO:0060326//cell chemotaxis;GO:0061154//endothelial tube morphogenesis;GO:0071345//cellular response to cytokine stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1903861//positive regulation of dendrite extension;GO:1905322//positive regulation of mesenchymal stem cell migration;GO:1990478//response to ultrasound;GO:2000448//positive regulation of macrophage migration inhibitory factor signaling pathway	--
ENSG00000121988	1.253	1.211	1.021	0.649	0.983	0.928	145	142	77	48	82	71	ZRANB3	zinc finger RANBP2-type containing 3 [Source:HGNC Symbol;Acc:HGNC:25249]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0043596//nuclear replication fork	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006281//DNA repair;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0009411//response to UV;GO:0031297//replication fork processing;GO:0036292//DNA rewinding;GO:0045910//negative regulation of DNA recombination;GO:0048478//replication fork protection;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000121989	2.041	2.217	1.806	1.356	2.078	2.167	171.82	175.45	99.18	95.28	138.25	108.19	ACVR2A	activin A receptor type 2A [Source:HGNC Symbol;Acc:HGNC:173]	Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K04670;K04670;K04670;K04670	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0043235//receptor complex;GO:0048179//activin receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015026//coreceptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017002//activin-activated receptor activity;GO:0019838//growth factor binding;GO:0030165//PDZ domain binding;GO:0034711//inhibin binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0098821//BMP receptor activity	GO:0001702//gastrulation with mouth forming second;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007283//spermatogenesis;GO:0007368//determination of left/right symmetry;GO:0007498//mesoderm development;GO:0008584//male gonad development;GO:0009952//anterior/posterior pattern specification;GO:0009966//regulation of signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016310//phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042713//sperm ejaculation;GO:0043084//penile erection;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048706//embryonic skeletal system development;GO:0050999//regulation of nitric-oxide synthase activity;GO:0060011//Sertoli cell proliferation;GO:0071363//cellular response to growth factor stimulus;GO:0071773//cellular response to BMP stimulus	--
ENSG00000122008	4.808	2.544	2.62	3.033	2.955	2.875	342	202	173	168	185	163	POLK	DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Replication and repair;Cancer: specific types	ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko03460//Fanconi anemia pathway;ko05216//Thyroid cancer	K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511;K03511	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0090734//site of DNA damage	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	"GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006301//postreplication repair;GO:0006974//cellular response to DNA damage stimulus;GO:0034644//cellular response to UV;GO:0042276//error-prone translesion synthesis;GO:0071897//DNA biosynthetic process"	--
ENSG00000122012	0.009	0	0	0.023	0.038	0.006	2	0	0	3	2	1	SV2C	synaptic vesicle glycoprotein 2C [Source:HGNC Symbol;Acc:HGNC:30670]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06258	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0055085//transmembrane transport	--
ENSG00000122025	1.525	1.241	1.228	1.327	2.014	1.801	121	99	72	78	135	104	FLT3	fms related receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Immune system;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04640//Hematopoietic cell lineage;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia	K05092;K05092;K05092;K05092;K05092;K05092;K05092;K05092	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004896//cytokine receptor activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0035259//glucocorticoid receptor binding;GO:0043621//protein self-association;GO:0044877//protein-containing complex binding	GO:0001776//leukocyte homeostasis;GO:0002318//myeloid progenitor cell differentiation;GO:0002328//pro-B cell differentiation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010243//response to organonitrogen compound;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0031100//animal organ regeneration;GO:0031401//positive regulation of protein modification process;GO:0033674//positive regulation of kinase activity;GO:0035726//common myeloid progenitor cell proliferation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042981//regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0046651//lymphocyte proliferation;GO:0046777//protein autophosphorylation;GO:0048584//positive regulation of response to stimulus;GO:0071345//cellular response to cytokine stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0097028//dendritic cell differentiation	--
ENSG00000122026	423.868	458.017	423.499	363.296	302.856	332.246	4982	5408	3676	3159	3010	2836	RPL21	ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:10313]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02889;K02889	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000122033	15.156	15.299	15.745	12.801	11.968	14.764	313.41	319	240	196	209	222	MTIF3	mitochondrial translational initiation factor 3 [Source:HGNC Symbol;Acc:HGNC:29788]	-	-	-	-	GO:0005739//mitochondrion	"GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0043022//ribosome binding;GO:0043024//ribosomal small subunit binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0032790//ribosome disassembly;GO:0070124//mitochondrial translational initiation	--
ENSG00000122034	62.003	59.605	59.171	53.339	53.035	54.099	1850.59	1787	1303	1175	1334	1177	GTF3A	general transcription factor IIIA [Source:HGNC Symbol;Acc:HGNC:4662]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0008097//5S rRNA binding;GO:0046872//metal ion binding	GO:0006383//transcription by RNA polymerase III;GO:0009303//rRNA transcription;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis	zf-C2H2
ENSG00000122035	0.19	0.075	0.103	0	0.045	0	10	4	4	0	2	0	RASL11A	RAS like family 11 member A [Source:HGNC Symbol;Acc:HGNC:23802]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0045943//positive regulation of transcription by RNA polymerase I	--
ENSG00000122042	15.333	12.844	12.52	11.745	12.201	14.075	1373	1156	828	779	923	917	UBL3	ubiquitin like 3 [Source:HGNC Symbol;Acc:HGNC:12504]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000122068	19.12	18.7	17.962	14.267	15.118	16.413	1376	1294	892	773	964	789	FYTTD1	forty-two-three domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25407]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006406//mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000122085	11.535	12.99	12.037	7.966	7.886	10.827	362.63	352.57	317.5	263.51	321.76	307.72	MTERF4	mitochondrial transcription termination factor 4 [Source:HGNC Symbol;Acc:HGNC:28785]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit;GO:0005829//cytosol	GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006364//rRNA processing;GO:0006390//mitochondrial transcription;GO:0006626//protein targeting to mitochondrion;GO:0007507//heart development;GO:0042255//ribosome assembly;GO:0043010//camera-type eye development"	--
ENSG00000122121	0	0	0	0	0	0	0	0	0	0	0	0	XPNPEP2	X-prolyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:12823]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14208	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis	--
ENSG00000122122	0	0	0	0	0.021	0	0	0	0	0	1	0	SASH3	SAM and SH3 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15975]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	"GO:0002639//positive regulation of immunoglobulin production;GO:0002726//positive regulation of T cell cytokine production;GO:0002821//positive regulation of adaptive immune response;GO:0030890//positive regulation of B cell proliferation;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042102//positive regulation of T cell proliferation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0046622//positive regulation of organ growth;GO:0048873//homeostasis of number of cells within a tissue;GO:0051251//positive regulation of lymphocyte activation"	--
ENSG00000122126	13.998	14.759	13.967	13.689	12.987	13.856	1487	1567	1088	1081	1158	1067	OCRL	OCRL inositol polyphosphate-5-phosphatase [Source:HGNC Symbol;Acc:HGNC:8108]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01099;K01099;K01099	GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005798//Golgi-associated vesicle;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042995//cell projection	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0031267//small GTPase binding;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0052745//inositol phosphate phosphatase activity"	GO:0001701//in utero embryonic development;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0019637//organophosphate metabolic process;GO:0030030//cell projection organization;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043087//regulation of GTPase activity;GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0060271//cilium assembly;GO:0061024//membrane organization	--
ENSG00000122133	0	0	0	0	0	0	0	0	0	0	0	0	PAEP	progestagen associated endometrial protein [Source:HGNC Symbol;Acc:HGNC:8573]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0036094//small molecule binding	GO:0006915//apoptotic process;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:1902491//negative regulation of sperm capacitation;GO:2000359//regulation of binding of sperm to zona pellucida	--
ENSG00000122136	0	0	0	0	0	0	0	0	0	0	0	0	OBP2A	odorant binding protein 2A [Source:HGNC Symbol;Acc:HGNC:23380]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005549//odorant binding;GO:0036094//small molecule binding	GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus	--
ENSG00000122140	30.161	31.894	30.116	33.796	37.012	36.15	915	981	682	767	960	811	MRPS2	mitochondrial ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:14495]	Genetic Information Processing	Translation	ko03010//Ribosome	K02967	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation;GO:0061668//mitochondrial ribosome assembly	--
ENSG00000122145	0.456	0.646	0.273	0.289	0.279	0.059	21	28	9	10	11	2	TBX22	T-box transcription factor 22 [Source:HGNC Symbol;Acc:HGNC:11600]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001708//cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	T-box
ENSG00000122176	1.327	1.369	1.486	2.388	2.288	2.769	81	84	67	108	118	123	FMOD	fibromodulin [Source:HGNC Symbol;Acc:HGNC:3774]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K08121	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0007181//transforming growth factor beta receptor complex assembly;GO:0030199//collagen fibril organization	--
ENSG00000122180	0	0.064	0	0	0	0	0	2	0	0	0	0	MYOG	myogenin [Source:HGNC Symbol;Acc:HGNC:7612]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0032993//protein-DNA complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001503//ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0008285//negative regulation of cell population proliferation;GO:0010831//positive regulation of myotube differentiation;GO:0014737//positive regulation of muscle atrophy;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0014891//striated muscle atrophy;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0014902//myotube differentiation;GO:0030154//cell differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0042692//muscle cell differentiation;GO:0042693//muscle cell fate commitment;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048741//skeletal muscle fiber development;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0051726//regulation of cell cycle;GO:0071285//cellular response to lithium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:1901739//regulation of myoblast fusion"	bHLH
ENSG00000122188	0	0	0	0	0	0	0	0	0	0	0	0	LAX1	lymphocyte transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:26005]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042169//SH2 domain binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0035556//intracellular signal transduction;GO:0042113//B cell activation;GO:0043407//negative regulation of MAP kinase activity;GO:0046649//lymphocyte activation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0051249//regulation of lymphocyte activation	--
ENSG00000122194	0.083	0.29	0.168	0	0.065	0.16	2	10	3	0	4	4	PLG	plasminogen [Source:HGNC Symbol;Acc:HGNC:9071]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01315;K01315;K01315;K01315	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0019897//extrinsic component of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0031232//extrinsic component of external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0034185//apolipoprotein binding;GO:0051087//chaperone binding;GO:1990405//protein antigen binding	"GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008285//negative regulation of cell population proliferation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0022617//extracellular matrix disassembly;GO:0042246//tissue regeneration;GO:0042730//fibrinolysis;GO:0045445//myoblast differentiation;GO:0046716//muscle cell cellular homeostasis;GO:0048771//tissue remodeling;GO:0051702//biological process involved in interaction with symbiont;GO:0051918//negative regulation of fibrinolysis;GO:0051919//positive regulation of fibrinolysis;GO:0060707//trophoblast giant cell differentiation;GO:0060716//labyrinthine layer blood vessel development;GO:0071674//mononuclear cell migration;GO:0099183//trans-synaptic signaling by BDNF, modulating synaptic transmission;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin"	--
ENSG00000122203	70.404	75.038	70.8	72.414	67.802	73.513	3566	3695.21	2772	2796	3056	2704	KIAA1191	KIAA1191 [Source:HGNC Symbol;Acc:HGNC:29209]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0008150//biological_process	--
ENSG00000122218	62.323	62.349	61.58	57.869	56.314	55.017	5846	5927	4287	3980	4540	3775	COPA	COPI coat complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:2230]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030426//growth cone;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005179//hormone activity;GO:0005198//structural molecule activity;GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030157//pancreatic juice secretion"	--
ENSG00000122223	0	0.118	0	0	0	0	0	3	0	0	0	0	CD244	CD244 molecule [Source:HGNC Symbol;Acc:HGNC:18171]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K06582	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042288//MHC class I protein binding	GO:0002250//adaptive immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0032729//positive regulation of interferon-gamma production;GO:0032757//positive regulation of interleukin-8 production;GO:0045087//innate immune response;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0071663//positive regulation of granzyme B production	--
ENSG00000122224	0	0	0	0	0	0	0	0	0	0	0	0	LY9	lymphocyte antigen 9 [Source:HGNC Symbol;Acc:HGNC:6730]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0032740//positive regulation of interleukin-17 production;GO:0042110//T cell activation;GO:0045087//innate immune response;GO:0072540//T-helper 17 cell lineage commitment	--
ENSG00000122254	0	0	0	0	0.025	0	0	0	0	0	1	0	HS3ST2	heparan sulfate-glucosamine 3-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:5195]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K07808	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity;GO:0033871//[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000122257	4.356	4.352	3.666	2.439	4.244	4.733	400	359	211	138	265	250	RBBP6	"RB binding protein 6, ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:9889]"	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001701//in utero embryonic development;GO:0006260//DNA replication;GO:0006275//regulation of DNA replication;GO:0006397//mRNA processing;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0035264//multicellular organism growth;GO:0048568//embryonic organ development;GO:0061053//somite development	--
ENSG00000122299	32.01	29.069	32.138	19.693	25.184	29.045	2066	1739	1379	916	1345	1335	ZC3H7A	zinc finger CCCH-type containing 7A [Source:HGNC Symbol;Acc:HGNC:30959]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding	GO:0010608//posttranscriptional regulation of gene expression;GO:0035196//production of miRNAs involved in gene silencing by miRNA	--
ENSG00000122304	0	0	0	0	0	0	0	0	0	0	0	0	PRM2	protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046870//cadmium ion binding	GO:0006323//DNA packaging;GO:0006997//nucleus organization;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0030261//chromosome condensation	--
ENSG00000122335	9.08	6.299	7.182	6.14	6.547	6.978	676	515	408	348	436	411	SERAC1	serine active site containing 1 [Source:HGNC Symbol;Acc:HGNC:21061]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0003674//molecular_function	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0030198//extracellular matrix organization;GO:0032367//intracellular cholesterol transport;GO:0036148//phosphatidylglycerol acyl-chain remodeling	--
ENSG00000122359	64.721	60.519	64.114	74.856	72.136	67.387	3324	3397	2631	3146	3508	2724	ANXA11	annexin A11 [Source:HGNC Symbol;Acc:HGNC:535]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K17095	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0042470//melanosome;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0045335//phagocytic vesicle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0023026//MHC class II protein complex binding;GO:0044548//S100 protein binding;GO:0048306//calcium-dependent protein binding	GO:0006909//phagocytosis;GO:0007049//cell cycle;GO:0032506//cytokinetic process;GO:0051301//cell division;GO:0051592//response to calcium ion	--
ENSG00000122367	0.151	0.102	0.036	0	0.063	0.03	7	7	2	0	3	1	LDB3	LIM domain binding 3 [Source:HGNC Symbol;Acc:HGNC:15710]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0030018//Z disc;GO:0031143//pseudopodium;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding	GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0045214//sarcomere organization;GO:0061061//muscle structure development	--
ENSG00000122375	0	0	0	0	0	0	0	0	0	0	0	0	OPN4	opsin 4 [Source:HGNC Symbol;Acc:HGNC:14449]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0097381//photoreceptor disc membrane;GO:1990913//sperm head plasma membrane	GO:0004930//G protein-coupled receptor activity;GO:0005502//11-cis retinal binding;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007634//optokinetic behavior;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0042752//regulation of circadian rhythm;GO:0043052//thermotaxis;GO:0048511//rhythmic process;GO:0050896//response to stimulus;GO:0050960//detection of temperature stimulus involved in thermoception;GO:0071482//cellular response to light stimulus;GO:1990384//hyaloid vascular plexus regression	--
ENSG00000122376	9.264	7.052	6.843	6.046	6.534	7.021	662.56	517.43	369.39	317.02	402.35	375	SHLD2	shieldin complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28773]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0002208//somatic diversification of immunoglobulins involved in immune response;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0043247//telomere maintenance in response to DNA damage;GO:0045830//positive regulation of isotype switching;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000122378	110.333	102.123	110.726	112.072	107.279	115.596	5917	5319	4381	4411	4689	4524	PRXL2A	peroxiredoxin like 2A [Source:HGNC Symbol;Acc:HGNC:28651]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0016209//antioxidant activity	GO:0045670//regulation of osteoclast differentiation;GO:0098869//cellular oxidant detoxification	--
ENSG00000122386	6.373	7.509	6.735	8.498	7.525	7.274	265	278	197	256	261	211	ZNF205	zinc finger protein 205 [Source:HGNC Symbol;Acc:HGNC:12996]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005739//mitochondrion	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway"	zf-C2H2
ENSG00000122390	30.107	31.722	33.883	35.233	34.641	38.344	1337	1310	1089	1139	1251	1159	NAA60	"N-alpha-acetyltransferase 60, NatF catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25875]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0004402//histone acetyltransferase activity;GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042803//protein homodimerization activity	GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006474//N-terminal protein amino acid acetylation;GO:0007059//chromosome segregation;GO:0008283//cell population proliferation;GO:0017196//N-terminal peptidyl-methionine acetylation;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation	--
ENSG00000122406	471.328	496.308	461.595	457.698	418.373	397.814	10033	10620	7257	7225	7527	6163	RPL5	ribosomal protein L5 [Source:HGNC Symbol;Acc:HGNC:10360]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02932;K02932	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008097//5S rRNA binding;GO:0019843//rRNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0048027//mRNA 5'-UTR binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0010628//positive regulation of gene expression;GO:0042273//ribosomal large subunit biogenesis;GO:0045727//positive regulation of translation;GO:0050821//protein stabilization;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000435//negative regulation of protein neddylation	--
ENSG00000122417	2.835	2.834	1.688	2.932	2.477	3.286	190	154	80	81	129	125	ODF2L	outer dense fiber of sperm tails 2 like [Source:HGNC Symbol;Acc:HGNC:29225]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection	-	GO:0030030//cell projection organization;GO:1902017//regulation of cilium assembly;GO:1902018//negative regulation of cilium assembly	--
ENSG00000122420	0.044	0.022	0	0.09	0	0	4	2	0	6	0	0	PTGFR	prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04072//Phospholipase D signaling pathway	K04262;K04262;K04262	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004958//prostaglandin F receptor activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007567//parturition;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043066//negative regulation of apoptotic process;GO:0050896//response to stimulus;GO:0071799//cellular response to prostaglandin D stimulus	--
ENSG00000122432	0	0	0	0	0	0	0	0	0	0	0	0	SPATA1	spermatogenesis associated 1 [Source:HGNC Symbol;Acc:HGNC:14682]	-	-	-	-	GO:0001669//acrosomal vesicle	-	-	--
ENSG00000122435	4.458	3.388	3.692	4.229	4.897	4.106	214.55	169.73	116.6	121.22	173.21	132.99	TRMT13	tRNA methyltransferase 13 homolog [Source:HGNC Symbol;Acc:HGNC:25502]	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106050//tRNA 2'-O-methyltransferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000122477	3.352	3.444	3.133	4.232	5.858	4.858	122.45	132.27	88.4	119.78	169.79	131.01	LRRC39	leucine rich repeat containing 39 [Source:HGNC Symbol;Acc:HGNC:28228]	-	-	-	-	GO:0005737//cytoplasm;GO:0031430//M band;GO:0043231//intracellular membrane-bounded organelle	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000122481	7.969	8.056	8.156	8.384	8.211	10.1	194.48	196.89	145.57	151.11	168.58	175.7	RWDD3	RWD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21393]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033235//positive regulation of protein sumoylation;GO:1902073//positive regulation of hypoxia-inducible factor-1alpha signaling pathway	--
ENSG00000122482	10.886	7.406	6.932	5.729	6.882	6.908	1001	646	481	384	548	470	ZNF644	zinc finger protein 644 [Source:HGNC Symbol;Acc:HGNC:29222]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000122483	0.368	0.127	0.21	0.12	0.287	0.126	21.4	10.3	6	3	9	5	CCDC18	coiled-coil domain containing 18 [Source:HGNC Symbol;Acc:HGNC:30370]	-	-	-	-	-	-	-	--
ENSG00000122484	0.824	0.545	0.533	0.535	0.483	0.612	289	192	138	139	143	156	RPAP2	RNA polymerase II associated protein 2 [Source:HGNC Symbol;Acc:HGNC:25791]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016591//RNA polymerase II, holoenzyme"	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0043175//RNA polymerase core enzyme binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0009301//snRNA transcription;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000122490	12.791	12.414	13.131	15.808	12.838	13.803	599	584	469	552	553	488	SLC66A2	solute carrier family 66 member 2 [Source:HGNC Symbol;Acc:HGNC:26188]	-	-	-	-	GO:0005768//endosome;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	"GO:0042147//retrograde transport, endosome to Golgi;GO:0045332//phospholipid translocation"	--
ENSG00000122507	6.702	5.687	6.499	4.897	4.183	5.513	404	368	227	206	235	262	BBS9	Bardet-Biedl syndrome 9 [Source:HGNC Symbol;Acc:HGNC:30000]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0034451//centriolar satellite;GO:0034464//BBSome;GO:0035869//ciliary transition zone;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007601//visual perception;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0045444//fat cell differentiation;GO:0050896//response to stimulus;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium	--
ENSG00000122512	13.373	12.467	13.694	9.632	11.975	9.647	1013	943	742	578	784	525	PMS2	"PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122]"	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03430//Mismatch repair	K10858;K10858	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032300//mismatch repair complex;GO:0032389//MutLalpha complex;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030983//mismatched DNA binding;GO:0032138//single base insertion or deletion binding;GO:0032407//MutSalpha complex binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000122515	9.777	11.036	9.381	12.136	12.724	11.934	796	893	575	739	861	734	ZMIZ2	zinc finger MIZ-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22229]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0043596//nuclear replication fork	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030374//nuclear receptor coactivator activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-MIZ
ENSG00000122543	0	0	0	0	0	0	0	0	0	0	0	0	OCM	oncomodulin [Source:HGNC Symbol;Acc:HGNC:8105]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000122545	42.944	38.803	36.297	23.068	28.772	29.987	1716	1545	1039	731	971	856	SEPTIN7	septin 7 [Source:HGNC Symbol;Acc:HGNC:1717]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K16944	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0016324//apical plasma membrane;GO:0030496//midbody;GO:0031105//septin complex;GO:0031514//motile cilium;GO:0032153//cell division site;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0097227//sperm annulus;GO:0097730//non-motile cilium"	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0016476//regulation of embryonic cell shape;GO:0030154//cell differentiation;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0060271//cilium assembly;GO:0061640//cytoskeleton-dependent cytokinesis;GO:1902857//positive regulation of non-motile cilium assembly	--
ENSG00000122547	0.738	0.852	0.745	0.703	0.92	0.701	53	72	45	38	53	32	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22223]	-	-	-	-	GO:0005886//plasma membrane;GO:0046658//anchored component of plasma membrane	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0010875//positive regulation of cholesterol efflux	--
ENSG00000122550	25.342	20.145	19.337	18.716	16.328	19.14	1300	1091	784	669	738	714	KLHL7	kelch like family member 7 [Source:HGNC Symbol;Acc:HGNC:15646]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0016567//protein ubiquitination	--
ENSG00000122557	6.98	7.686	7.649	6.655	7.013	8.723	379	394	296	226	335	313	HERPUD2	HERPUD family member 2 [Source:HGNC Symbol;Acc:HGNC:21915]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006986//response to unfolded protein;GO:0007283//spermatogenesis;GO:0030968//endoplasmic reticulum unfolded protein response	--
ENSG00000122565	39.856	36.858	34.549	31.495	31.192	33.017	1664	1548.78	1063	958	1092	1001.17	CBX3	chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K11586	"GO:0000775//chromosome, centromeric region;GO:0000779//condensed chromosome, centromeric region;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005819//spindle;GO:0061793//chromatin lock complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:0090734//site of DNA damage"	GO:0001221//transcription coregulator binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:1990226//histone methyltransferase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0031507//heterochromatin assembly;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000122566	135.452	122.742	141.601	129.785	128.905	163.117	7087.36	6395.02	5523.01	4991.89	5678.39	6147.66	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K13158	"GO:0000781//chromosome, telomeric region;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex"	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0042802//identical protein binding;GO:0043047//single-stranded telomeric DNA binding;GO:0097157//pre-mRNA intronic binding;GO:0098505//G-rich strand telomeric DNA binding;GO:1990247//N6-methyladenosine-containing RNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0031053//primary miRNA processing;GO:0044806//G-quadruplex DNA unwinding;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0050658//RNA transport;GO:0051028//mRNA transport;GO:1904358//positive regulation of telomere maintenance via telomere lengthening;GO:1905663//positive regulation of telomerase RNA reverse transcriptase activity;GO:1990428//miRNA transport"	--
ENSG00000122574	0.16	0.193	0.201	0.123	0.108	0.251	14	17	13	8	8	16	WIPF3	WAS/WASL interacting protein family member 3 [Source:HGNC Symbol;Acc:HGNC:22004]	Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko04144//Endocytosis;ko05135//Yersinia infection	K19475;K19475;K19475	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005884//actin filament	GO:0003779//actin binding;GO:0017124//SH3 domain binding	GO:0007283//spermatogenesis;GO:0030048//actin filament-based movement;GO:0030154//cell differentiation	--
ENSG00000122584	0	0	0.02	0	0	0	0	0	1	0	0	0	NXPH1	neurexophilin 1 [Source:HGNC Symbol;Acc:HGNC:20693]	-	-	-	-	GO:0005576//extracellular region	GO:0005102//signaling receptor binding	-	--
ENSG00000122585	0	0	0	0.117	0	0	0	0	0	1	0	0	NPY	neuropeptide Y [Source:HGNC Symbol;Acc:HGNC:7955]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Substance dependence;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04920//Adipocytokine signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K05232;K05232;K05232;K05232;K05232	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm;GO:0098992//neuronal dense core vesicle	GO:0001664//G protein-coupled receptor binding;GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0031841//neuropeptide Y receptor binding	"GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007568//aging;GO:0007631//feeding behavior;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0008343//adult feeding behavior;GO:0010811//positive regulation of cell-substrate adhesion;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0031175//neuron projection development;GO:0032100//positive regulation of appetite;GO:0032903//regulation of nerve growth factor production;GO:0042117//monocyte activation;GO:0045776//negative regulation of blood pressure;GO:0045964//positive regulation of dopamine metabolic process;GO:0048572//short-day photoperiodism;GO:0050909//sensory perception of taste;GO:0060575//intestinal epithelial cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1901215//negative regulation of neuron death;GO:1904000//positive regulation of eating behavior;GO:1904407//positive regulation of nitric oxide metabolic process"	--
ENSG00000122591	36.237	32.137	30.045	33.562	32.049	39.575	2702	2199	1734	1576	1709	1903	FAM126A	family with sequence similarity 126 member A [Source:HGNC Symbol;Acc:HGNC:24587]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043005//neuron projection	GO:0005515//protein binding	GO:0042552//myelination;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000122592	0	0.024	0	0	0.028	0	0	1	0	0	1	0	HOXA7	homeobox A7 [Source:HGNC Symbol;Acc:HGNC:5108]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001953//negative regulation of cell-matrix adhesion;GO:0002686//negative regulation of leukocyte migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0045617//negative regulation of keratinocyte differentiation;GO:0045656//negative regulation of monocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048863//stem cell differentiation"	Homeobox
ENSG00000122641	7.663	6.767	2.958	1.179	1.402	1.026	961	853	274	86	146	82	INHBA	inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04667;K04667;K04667	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043509//activin A complex;GO:0043512//inhibin A complex;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0017046//peptide hormone binding;GO:0034711//inhibin binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0070699//type II activin receptor binding	"GO:0001541//ovarian follicle development;GO:0001707//mesoderm formation;GO:0001942//hair follicle development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0021773//striatal medium spiny neuron differentiation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030308//negative regulation of cell growth;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032689//negative regulation of interferon-gamma production;GO:0032924//activin receptor signaling pathway;GO:0035987//endodermal cell differentiation;GO:0042326//negative regulation of phosphorylation;GO:0042476//odontogenesis;GO:0042541//hemoglobin biosynthetic process;GO:0042701//progesterone secretion;GO:0045578//negative regulation of B cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046880//regulation of follicle-stimulating hormone secretion;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0048333//mesodermal cell differentiation;GO:0051799//negative regulation of hair follicle development;GO:0060021//roof of mouth development;GO:0060279//positive regulation of ovulation;GO:0060395//SMAD protein signal transduction;GO:0061029//eyelid development in camera-type eye;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071397//cellular response to cholesterol;GO:0097154//GABAergic neuron differentiation;GO:0097191//extrinsic apoptotic signaling pathway;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000122642	32.711	34.546	31.548	31.798	37.031	24.966	1925	2130	1415	1367	1638	1197	FKBP9	FKBP prolyl isomerase 9 [Source:HGNC Symbol;Acc:HGNC:3725]	-	-	-	-	GO:0005783//endoplasmic reticulum	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000122643	4.603	4.256	4.543	4.227	3.263	3.733	157	143	118	109	98	94	NT5C3A	"5'-nucleotidase, cytosolic IIIA [Source:HGNC Symbol;Acc:HGNC:17820]"	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K24242;K24242	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0000215//tRNA 2'-phosphotransferase activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008253//5'-nucleotidase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006213//pyrimidine nucleoside metabolic process;GO:0006248//CMP catabolic process;GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0051607//defense response to virus	--
ENSG00000122644	16.032	16.664	16.13	18.463	15.74	20.386	591	628	374	486	506	514	ARL4A	ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0050873//brown fat cell differentiation	--
ENSG00000122674	9.928	9.323	9.214	7.654	8.436	11.91	489.9	460.55	335.79	279.77	350.87	427.01	CCZ1	"CCZ1 homolog, vacuolar protein trafficking and biogenesis associated [Source:HGNC Symbol;Acc:HGNC:21691]"	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0035658//Mon1-Ccz1 complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000122678	3.746	5.236	4.495	3.969	3.556	3.706	167	174	130	127	136	138	POLM	DNA polymerase mu [Source:HGNC Symbol;Acc:HGNC:9185]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K03513	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0034061//DNA polymerase activity;GO:0046872//metal ion binding	GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0071897//DNA biosynthetic process	--
ENSG00000122679	0	0.29	0	0.197	0.21	0.05	0	8	0	4	2	1	RAMP3	receptor activity modifying protein 3 [Source:HGNC Symbol;Acc:HGNC:9845]	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K08449	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0150058//amylin receptor complex 3;GO:1903143//adrenomedullin receptor complex	GO:0001540//amyloid-beta binding;GO:0001605//adrenomedullin receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0097643//amylin receptor activity	GO:0001921//positive regulation of receptor recycling;GO:0006816//calcium ion transport;GO:0006886//intracellular protein transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010739//positive regulation of protein kinase A signaling;GO:0010942//positive regulation of cell death;GO:0015031//protein transport;GO:0031623//receptor internalization;GO:0032870//cellular response to hormone stimulus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038041//cross-receptor inhibition within G protein-coupled receptor heterodimer;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071392//cellular response to estradiol stimulus;GO:0072659//protein localization to plasma membrane;GO:0086103//G protein-coupled receptor signaling pathway involved in heart process;GO:0097647//amylin receptor signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904645//response to amyloid-beta;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1990410//adrenomedullin receptor signaling pathway	--
ENSG00000122687	11.04	11.603	11.738	11.293	10.587	11.585	410	456	325.98	306	336	323	MRM2	mitochondrial rRNA methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16352]	-	-	-	-	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008650//rRNA (uridine-2'-O-)-methyltransferase activity;GO:0016740//transferase activity	GO:0000451//rRNA 2'-O-methylation;GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0043414//macromolecule methylation	--
ENSG00000122691	0.351	0.324	0.28	0.534	0.169	0.251	8	11	7	10	4	2	TWIST1	twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K09069	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001764//neuron migration;GO:0001843//neural tube closure;GO:0003180//aortic valve morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030500//regulation of bone mineralization;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0032502//developmental process;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033128//negative regulation of histone phosphorylation;GO:0035067//negative regulation of histone acetylation;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0042473//outer ear morphogenesis;GO:0042476//odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0044092//negative regulation of molecular function;GO:0045596//negative regulation of cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045843//negative regulation of striated muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060348//bone development;GO:0060363//cranial suture morphogenesis;GO:0060900//embryonic camera-type eye formation;GO:0061029//eyelid development in camera-type eye;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0071456//cellular response to hypoxia;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:2000147//positive regulation of cell motility;GO:2000276//negative regulation of oxidative phosphorylation uncoupler activity;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2000773//negative regulation of cellular senescence;GO:2000780//negative regulation of double-strand break repair;GO:2000793//cell proliferation involved in heart valve development;GO:2000802//positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation"	bHLH
ENSG00000122692	5.256	5.774	5.772	4.305	4.902	5.785	778	859	631	472	613	623	SMU1	SMU1 DNA replication regulator and spliceosomal factor [Source:HGNC Symbol;Acc:HGNC:18247]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000122694	8.049	8.479	7.027	4.499	5.82	5.507	305	335	194	131	179	152	GLIPR2	GLI pathogenesis related 2 [Source:HGNC Symbol;Acc:HGNC:18007]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0042803//protein homodimerization activity	GO:0010634//positive regulation of epithelial cell migration;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000122696	3.607	3.801	3.186	2.972	3.139	3.767	94	107	60	58	71	70	SLC25A51	solute carrier family 25 member 51 [Source:HGNC Symbol;Acc:HGNC:23323]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0051724//NAD transmembrane transporter activity	GO:0019646//aerobic electron transport chain;GO:1990549//mitochondrial NAD transmembrane transport	--
ENSG00000122705	124.84	120.321	117.909	125.47	115.282	102.03	2798	2711	1950	2083	2181	1662	CLTA	clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Transport and catabolism;Infectious disease: bacterial;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04142//Lysosome;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K04644;K04644;K04644;K04644;K04644;K04644	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030118//clathrin coat;GO:0030125//clathrin vesicle coat;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0036020//endolysosome membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0071439//clathrin complex;GO:0098835//presynaptic endocytic zone membrane;GO:0099631//postsynaptic endocytic zone cytoplasmic component	GO:0003674//molecular_function;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0032050//clathrin heavy chain binding;GO:0042277//peptide binding;GO:0044877//protein-containing complex binding;GO:0051020//GTPase binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007049//cell cycle;GO:0016192//vesicle-mediated transport;GO:0048268//clathrin coat assembly;GO:0051301//cell division;GO:0072583//clathrin-dependent endocytosis	--
ENSG00000122707	4.087	3.414	3.107	2.788	4.165	3.439	374	314	210	189	322	229	RECK	reversion inducing cysteine rich protein with kazal motifs [Source:HGNC Symbol;Acc:HGNC:11345]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17461	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:1990909//Wnt signalosome	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0017147//Wnt-protein binding;GO:0030414//peptidase inhibitor activity;GO:1904928//coreceptor activity involved in canonical Wnt signaling pathway	GO:0001955//blood vessel maturation;GO:0002040//sprouting angiogenesis;GO:0007566//embryo implantation;GO:0010466//negative regulation of peptidase activity;GO:0016055//Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0030336//negative regulation of cell migration;GO:0035115//embryonic forelimb morphogenesis;GO:0045765//regulation of angiogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0090210//regulation of establishment of blood-brain barrier;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904684//negative regulation of metalloendopeptidase activity	--
ENSG00000122711	0	0	0	0	0	0	0	0	0	0	0	0	SPINK4	serine peptidase inhibitor Kazal type 4 [Source:HGNC Symbol;Acc:HGNC:16646]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000122728	0	0	0	0	0	0	0	0	0	0	0	0	TAF1L	TATA-box binding protein associated factor 1 like [Source:HGNC Symbol;Acc:HGNC:18056]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03125	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex	GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0070577//lysine-acetylated histone binding	"GO:0006352//DNA-templated transcription, initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007140//male meiotic nuclear division;GO:0016573//histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000122729	32.694	34.556	31.532	31.573	31.932	33.505	2612	2785	1871	1853	2156	1981	ACO1	aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K01681;K01681;K01681;K01681;K01681;K01681	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003994//aconitate hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0030350//iron-responsive element binding;GO:0046872//metal ion binding;GO:0047780//citrate dehydratase activity;GO:0051536//iron-sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006099//tricarboxylic acid cycle;GO:0006101//citrate metabolic process;GO:0006417//regulation of translation;GO:0006879//cellular iron ion homeostasis;GO:0009791//post-embryonic development;GO:0010040//response to iron(II) ion;GO:0010468//regulation of gene expression;GO:0050892//intestinal absorption	--
ENSG00000122733	0	0.042	0	0.057	0.02	0.058	0	5	0	5	2	5	PHF24	PHD finger protein 24 [Source:HGNC Symbol;Acc:HGNC:29180]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain"	--
ENSG00000122735	0.476	0.212	0.101	0	0.379	0.128	13	7	4	0	11	2	DNAI1	dynein axonemal intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2954]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10409;K10409;K10409	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0097729//9+2 motile cilium;GO:0120293//dynein axonemal particle	GO:0003774//cytoskeletal motor activity;GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007018//microtubule-based movement;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008286//insulin receptor signaling pathway;GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility;GO:0036158//outer dynein arm assembly	--
ENSG00000122741	5.964	4.69	4.36	3.556	4.085	4.576	978	773	528	432	566	546	DCAF10	DDB1 and CUL4 associated factor 10 [Source:HGNC Symbol;Acc:HGNC:23686]	-	-	-	-	GO:0005654//nucleoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000122756	0.126	0.071	0.205	0.803	0.624	0.585	5	3	6	15	12	18	CNTFR	ciliary neurotrophic factor receptor [Source:HGNC Symbol;Acc:HGNC:2170]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05059;K05059	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0043235//receptor complex;GO:0070110//ciliary neurotrophic factor receptor complex;GO:0097059//CNTFR-CLCF1 complex	GO:0004896//cytokine receptor activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0001967//suckling behavior;GO:0003360//brainstem development;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007548//sex differentiation;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0050896//response to stimulus;GO:0060538//skeletal muscle organ development;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway	--
ENSG00000122778	3.854	3.972	3.844	2.801	3.422	3.664	995	1033	735	537	747	689	KIAA1549	KIAA1549 [Source:HGNC Symbol;Acc:HGNC:22219]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection	-	-	Others
ENSG00000122779	6.158	5.947	4.467	3.635	3.767	4.178	610	581	326	277	335	297	TRIM24	tripartite motif containing 24 [Source:HGNC Symbol;Acc:HGNC:11812]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005726//perichromatin fibrils;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004672//protein kinase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016922//nuclear receptor binding;GO:0034056//estrogen response element binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0070577//lysine-acetylated histone binding	"GO:0006366//transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0031647//regulation of protein stability;GO:0042981//regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0055074//calcium ion homeostasis;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0071391//cellular response to estrogen stimulus;GO:1901796//regulation of signal transduction by p53 class mediator"	--
ENSG00000122783	19.834	18.413	22.79	19.819	20.949	24.628	672.27	597.81	545.35	485.04	571.68	560.81	CYREN	cell cycle regulator of NHEJ [Source:HGNC Symbol;Acc:HGNC:22432]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0033152//immunoglobulin V(D)J recombination;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000122786	212.358	184.26	148.729	101.592	128.349	130.632	14332	12215	7431	5168	7040	6388	CALD1	caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441]	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K12327	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030016//myofibril;GO:0030478//actin cap	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005523//tropomyosin binding;GO:0008092//cytoskeletal protein binding;GO:0017022//myosin binding;GO:0045296//cadherin binding	GO:0001525//angiogenesis;GO:0006936//muscle contraction;GO:0051017//actin filament bundle assembly	--
ENSG00000122787	0	0	0	0	0	0	0	0	0	0	0	0	AKR1D1	aldo-keto reductase family 1 member D1 [Source:HGNC Symbol;Acc:HGNC:388]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko00120//Primary bile acid biosynthesis	K00251;K00251;K00251	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0005496//steroid binding;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047787//delta4-3-oxosteroid 5beta-reductase activity;GO:0102196//cortisol dehydrogenase activity	GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006707//cholesterol catabolic process;GO:0007586//digestion;GO:0008202//steroid metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0008209//androgen metabolic process;GO:0016042//lipid catabolic process;GO:0030573//bile acid catabolic process	--
ENSG00000122824	1.603	1.095	1.095	1.15	1.275	0.971	64	43.94	32.28	34	43	28.22	NUDT10	nudix hydrolase 10 [Source:HGNC Symbol;Acc:HGNC:17621]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000298//endopolyphosphatase activity;GO:0005515//protein binding;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity	GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	--
ENSG00000122852	0	0	0	0	0	0	0	0	0	0	0	0	SFTPA1	surfactant protein A1 [Source:HGNC Symbol;Acc:HGNC:10798]	Cellular Processes;Human Diseases	Transport and catabolism;Infectious disease: bacterial	ko04145//Phagosome;ko05133//Pertussis	K10067;K10067	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005771//multivesicular body;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0042599//lamellar body;GO:0045334//clathrin-coated endocytic vesicle	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006869//lipid transport;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008228//opsonization	--
ENSG00000122859	0	0	0	0	0	0	0	0	0	0	0	0	NEUROG3	neurogenin 3 [Source:HGNC Symbol;Acc:HGNC:13806]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08028	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0021510//spinal cord development;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030855//epithelial cell differentiation;GO:0030900//forebrain development;GO:0030902//hindbrain development;GO:0031018//endocrine pancreas development;GO:0045597//positive regulation of cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048814//regulation of dendrite morphogenesis;GO:0060290//transdifferentiation"	bHLH
ENSG00000122861	4.342	4.032	1.699	4.222	4.774	2.969	211	198	61	152	196	105	PLAU	"plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Cancer: overview;Signal transduction;Cancer: overview;Cancer: specific types;Immune system	ko05202//Transcriptional misregulation in cancer;ko05205//Proteoglycans in cancer;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko05215//Prostate cancer;ko04610//Complement and coagulation cascades	K01348;K01348;K01348;K01348;K01348;K01348	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0097180//serine protease inhibitor complex;GO:0098637//protein complex involved in cell-matrix adhesion;GO:1905370//serine-type endopeptidase complex	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001666//response to hypoxia;GO:0006508//proteolysis;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010469//regulation of signaling receptor activity;GO:0010755//regulation of plasminogen activation;GO:0010757//negative regulation of plasminogen activation;GO:0014909//smooth muscle cell migration;GO:0014910//regulation of smooth muscle cell migration;GO:0030155//regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0031639//plasminogen activation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0038195//urokinase plasminogen activator signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042730//fibrinolysis;GO:0051917//regulation of fibrinolysis;GO:0051918//negative regulation of fibrinolysis;GO:0061041//regulation of wound healing;GO:2000097//regulation of smooth muscle cell-matrix adhesion	--
ENSG00000122862	0.396	0.512	0.107	0.053	0.516	0.054	10	13	2	1	11	1	SRGN	serglycin [Source:HGNC Symbol;Acc:HGNC:9361]	-	-	-	-	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0030141//secretory granule;GO:0031093//platelet alpha granule lumen;GO:0042629//mast cell granule;GO:0044194//cytolytic granule;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099091//postsynaptic specialization, intracellular component"	GO:0005515//protein binding	GO:0001818//negative regulation of cytokine production;GO:0006915//apoptotic process;GO:0016485//protein processing;GO:0030502//negative regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0033363//secretory granule organization;GO:0033364//mast cell secretory granule organization;GO:0033371//T cell secretory granule organization;GO:0033373//maintenance of protease location in mast cell secretory granule;GO:0033382//maintenance of granzyme B location in T cell secretory granule;GO:0050804//modulation of chemical synaptic transmission;GO:0099175//regulation of postsynapse organization;GO:0140507//granzyme-mediated programmed cell death signaling pathway	--
ENSG00000122863	19.767	20.738	21.483	22.725	22.574	27.473	2843	2998	2282	2421	2743	2875	CHST3	carbohydrate sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:1971]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K01020	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0008459//chondroitin 6-sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000122870	2.956	2.122	2.12	1.111	1.223	1.304	352	254	167	98	123	113	BICC1	BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0001822//kidney development;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000122873	11.794	10.259	9.95	10.743	9.347	10.797	581	508	362	392	389	387	CISD1	CDGSH iron sulfur domain 1 [Source:HGNC Symbol;Acc:HGNC:30880]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0010506//regulation of autophagy;GO:0043457//regulation of cellular respiration	--
ENSG00000122877	0.065	0.067	0.044	0.047	0.077	0.049	4	4	2	2	2	2	EGR2	early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system	ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04625//C-type lectin receptor signaling pathway	K12496;K12496;K12496;K12496	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061665//SUMO ligase activity;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006611//protein export from nucleus;GO:0007420//brain development;GO:0007422//peripheral nervous system development;GO:0007611//learning or memory;GO:0007622//rhythmic behavior;GO:0008045//motor neuron axon guidance;GO:0010467//gene expression;GO:0014037//Schwann cell differentiation;GO:0014040//positive regulation of Schwann cell differentiation;GO:0016925//protein sumoylation;GO:0021569//rhombomere 3 development;GO:0021612//facial nerve structural organization;GO:0021659//rhombomere 3 structural organization;GO:0021660//rhombomere 3 formation;GO:0021665//rhombomere 5 structural organization;GO:0021666//rhombomere 5 formation;GO:0030278//regulation of ossification;GO:0031643//positive regulation of myelination;GO:0032868//response to insulin;GO:0035284//brain segmentation;GO:0035904//aorta development;GO:0035914//skeletal muscle cell differentiation;GO:0042552//myelination;GO:0045444//fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048168//regulation of neuronal synaptic plasticity;GO:0071310//cellular response to organic substance"	zf-C2H2
ENSG00000122882	10.572	10.263	10.797	9.054	8.177	9.374	601	570	447	337	401	370	ECD	ecdysoneless cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:17029]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding	GO:0006397//mRNA processing;GO:0008283//cell population proliferation;GO:0008380//RNA splicing;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000122884	71.488	75.571	60.987	53.413	60.969	53.475	4083	4343	2563	2257	2948	2225	P4HA1	prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00472;K00472	GO:0005581//collagen trimer;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0019511//peptidyl-proline hydroxylation;GO:0030199//collagen fibril organization	--
ENSG00000122912	3.029	3.231	2.967	2.157	3.379	4.668	282	293	227	163	211	231	SLC25A16	solute carrier family 25 member 16 [Source:HGNC Symbol;Acc:HGNC:10986]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015291//secondary active transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006839//mitochondrial transport;GO:0015937//coenzyme A biosynthetic process;GO:0055085//transmembrane transport	--
ENSG00000122952	3.84	4.138	5.078	4.723	3.615	3.822	141	160	144	119	102	107	ZWINT	ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0031617//NMS complex"	GO:0005515//protein binding;GO:0047485//protein N-terminus binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007093//mitotic cell cycle checkpoint signaling;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0051301//cell division;GO:0051649//establishment of localization in cell	--
ENSG00000122958	15.046	14.985	13.951	11.801	11.941	14.265	971	912	617	564	628	618	VPS26A	"VPS26, retromer complex component A [Source:HGNC Symbol;Acc:HGNC:12711]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18466	"GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030904//retromer complex;GO:0030906//retromer, cargo-selective complex;GO:0031982//vesicle;GO:0097422//tubular endosome"	GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000122965	8.908	9.163	8.504	6.754	8.192	7.104	727	740	503	404	558	429	RBM19	RNA binding motif protein 19 [Source:HGNC Symbol;Acc:HGNC:29098]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0040019//positive regulation of embryonic development"	--
ENSG00000122966	0.093	0.191	0.157	0.296	0.147	0.089	15	26	10	20	18	7	CIT	citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031985//Golgi cisterna;GO:0032154//cleavage furrow;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0001223//transcription coactivator binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001889//liver development;GO:0006468//protein phosphorylation;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0008064//regulation of actin polymerization or depolymerization;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030154//cell differentiation;GO:0031032//actomyosin structure organization;GO:0032467//positive regulation of cytokinesis;GO:0035331//negative regulation of hippo signaling;GO:0043086//negative regulation of catalytic activity;GO:0048699//generation of neurons;GO:0051301//cell division;GO:0051402//neuron apoptotic process	--
ENSG00000122970	8.744	7.293	6.268	5.331	5.658	6.564	483	439	266	236	273	284	IFT81	intraflagellar transport 81 [Source:HGNC Symbol;Acc:HGNC:14313]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097542//ciliary tip	GO:0005515//protein binding;GO:0015631//tubulin binding	GO:0007283//spermatogenesis;GO:0008589//regulation of smoothened signaling pathway;GO:0030030//cell projection organization;GO:0035720//intraciliary anterograde transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0120316//sperm flagellum assembly	--
ENSG00000122971	6.094	6.063	6.215	8.053	7.858	7.164	235	235	177	230	256	201	ACADS	acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Lipid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko00650//Butanoate metabolism"	K00248;K00248;K00248;K00248;K00248;K00248;K00248;K00248	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005813//centrosome	"GO:0003995//acyl-CoA dehydrogenase activity;GO:0004085//butyryl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046359//butyrate catabolic process	--
ENSG00000122986	1.933	3.134	3.281	2.569	2.998	2.304	61.28	95.84	65.08	58	74.93	52.43	HVCN1	hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0035579//specific granule membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0022843//voltage-gated cation channel activity;GO:0030171//voltage-gated proton channel activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0009268//response to pH;GO:0010043//response to zinc ion;GO:0032930//positive regulation of superoxide anion generation;GO:0034765//regulation of ion transmembrane transport;GO:0045454//cell redox homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071294//cellular response to zinc ion;GO:0071467//cellular response to pH;GO:1902600//proton transmembrane transport	--
ENSG00000123064	23.312	27.492	25.144	26.407	25.264	26.5	1489.69	1638.85	1286.07	1244.9	1359.7	1126.91	DDX54	DEAD-box helicase 54 [Source:HGNC Symbol;Acc:HGNC:20084]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005102//signaling receptor binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030331//estrogen receptor binding	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0016070//RNA metabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000123066	7.613	7.07	7.234	5.596	7.439	7.121	1374	1292	919	756	999	885	MED13L	mediator complex subunit 13L [Source:HGNC Symbol;Acc:HGNC:22962]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15164	GO:0005634//nucleus;GO:0016592//mediator complex	GO:0003712//transcription coregulator activity	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000123080	1.085	1.463	1.514	1.299	1.081	1.556	36	55	36	31	33	34	CDKN2C	cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Drug resistance: antineoplastic	ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko04934//Cushing syndrome;ko04110//Cell cycle;ko01522//Endocrine resistance	K06622;K06622;K06622;K06622;K06622	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0042326//negative regulation of phosphorylation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048709//oligodendrocyte differentiation;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000123091	52.07	45.031	46.357	42.918	38.093	47.508	3320	2886	2183	2027	2052	2204	RNF11	ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination	--
ENSG00000123094	60.114	40.573	43.447	31.832	38.368	47.338	5492	3842	3047	2326	2819	3123	RASSF8	Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000123095	15.212	16.172	10.464	12.207	11.556	11.914	1181	1262	600	702	758	673	BHLHE41	basic helix-loop-helix family member e41 [Source:HGNC Symbol;Acc:HGNC:16617]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K03730	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043425//bHLH transcription factor binding;GO:0043426//MRF binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0009952//anterior/posterior pattern specification;GO:0010832//negative regulation of myotube differentiation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000123096	9.026	6.888	5.638	6.98	6.562	5.81	774	615	382	344	492	390	SSPN	sarcospan [Source:HGNC Symbol;Acc:HGNC:11322]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030133//transport vesicle;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0045211//postsynaptic membrane	-	GO:0006936//muscle contraction;GO:0007155//cell adhesion	--
ENSG00000123104	1.853	1.206	1.039	1.286	1.113	1.023	420	316	200	224	245	194	ITPR2	"inositol 1,4,5-trisphosphate receptor type 2 [Source:HGNC Symbol;Acc:HGNC:6181]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Nervous system;Neurodegenerative disease;Cell growth and death;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine system;Nervous system;Nervous system;Nervous system;Immune system;Endocrine system;Endocrine system;Digestive system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Digestive system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04114//Oocyte meiosis;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression"	K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959;K04959	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031095//platelet dense tubular network membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0043235//receptor complex	"GO:0005216//ion channel activity;GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0015085//calcium ion transmembrane transporter activity;GO:0015278//calcium-release channel activity;GO:0035091//phosphatidylinositol binding;GO:0044325//transmembrane transporter binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0097110//scaffold protein binding"	GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0048016//inositol phosphate-mediated signaling;GO:0051209//release of sequestered calcium ion into cytosol;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071361//cellular response to ethanol	--
ENSG00000123106	5.881	6.212	6.367	4.201	4.208	5.349	297	303	228	153	176	192	CCDC91	coiled-coil domain containing 91 [Source:HGNC Symbol;Acc:HGNC:24855]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane	-	GO:0015031//protein transport;GO:0048193//Golgi vesicle transport;GO:0090160//Golgi to lysosome transport	--
ENSG00000123119	3.119	2.809	2.208	1.552	1.499	1.989	326.63	291.4	170.78	120.36	132.61	151.53	NECAB1	N-terminal EF-hand calcium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20983]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001835//blastocyst hatching;GO:0008150//biological_process;GO:0042984//regulation of amyloid precursor protein biosynthetic process	--
ENSG00000123124	14.41	12.961	12.618	10.96	10.888	12.302	1142	1005	720	602	707	689	WWP1	WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04144//Endocytosis;ko04120//Ubiquitin mediated proteolysis	K05633;K05633	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0016567//protein ubiquitination;GO:0034220//ion transmembrane transport;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell"	--
ENSG00000123130	13.697	13.427	12.077	13.388	13.022	12.973	618	590	401	469	535	410	ACOT9	acyl-CoA thioesterase 9 [Source:HGNC Symbol;Acc:HGNC:17152]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003986//acetyl-CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006637//acyl-CoA metabolic process	--
ENSG00000123131	82.077	83.186	84.396	75.162	75.878	68.201	1627	1658	1236	1104	1271	984	PRDX4	peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169]	Cellular Processes	Cell growth and death	ko04214//Apoptosis - fly	K03386	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0051920//peroxiredoxin activity	GO:0006979//response to oxidative stress;GO:0007252//I-kappaB phosphorylation;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0022417//protein maturation by protein folding;GO:0030198//extracellular matrix organization;GO:0045454//cell redox homeostasis;GO:0072593//reactive oxygen species metabolic process;GO:0098869//cellular oxidant detoxification;GO:2000255//negative regulation of male germ cell proliferation	--
ENSG00000123136	18.68	17.231	17.384	15.799	16.903	17.344	525	495	358	333	427	367	DDX39A	DExD-box helicase 39A [Source:HGNC Symbol;Acc:HGNC:17821]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing"	--
ENSG00000123143	49.704	52.144	52.8	58.43	56.137	56.614	3191	3328	2472	2732	3037	2599	PKN1	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Immune system	ko04151//PI3K-Akt signaling pathway;ko05132//Salmonella infection;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway	K06071;K06071;K06071;K06071	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030374//nuclear receptor coactivator activity;GO:0031267//small GTPase binding;GO:0035402//histone kinase activity (H3-T11 specific);GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0050681//androgen receptor binding;GO:0106310//protein serine kinase activity	"GO:0001782//B cell homeostasis;GO:0001783//B cell apoptotic process;GO:0001933//negative regulation of protein phosphorylation;GO:0002634//regulation of germinal center formation;GO:0002637//regulation of immunoglobulin production;GO:0003014//renal system process;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006972//hyperosmotic response;GO:0007165//signal transduction;GO:0010631//epithelial cell migration;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030889//negative regulation of B cell proliferation;GO:0035407//histone H3-T11 phosphorylation;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0060765//regulation of androgen receptor signaling pathway;GO:2000145//regulation of cell motility"	--
ENSG00000123144	119.711	124.294	142.818	148.14	126.963	125.304	2186	2281	1925	2002	1958	1663	TRIR	telomerase RNA component interacting RNase [Source:HGNC Symbol;Acc:HGNC:28424]	-	-	-	-	-	GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity	"GO:0016075//rRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000123146	0.792	1.012	0.719	0.511	0.569	0.438	47	46	33	24	23	19	ADGRE5	adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling	--
ENSG00000123154	6.918	6.847	6.303	7.092	5.47	8.252	208	207	140	158	139	176	WDR83	WD repeat domain 83 [Source:HGNC Symbol;Acc:HGNC:32672]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0010008//endosome membrane;GO:0071013//catalytic step 2 spliceosome	GO:0005515//protein binding;GO:0016301//kinase activity	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0001666//response to hypoxia;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0009611//response to wounding;GO:0016310//phosphorylation;GO:0032496//response to lipopolysaccharide;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0090594//inflammatory response to wounding"	--
ENSG00000123159	78.764	84.446	92.804	104.25	103.847	113.192	2922	2970	2425	2787	3208	2955	GIPC1	GIPC PDZ domain containing family member 1 [Source:HGNC Symbol;Acc:HGNC:1226]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0008021//synaptic vesicle;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	GO:0006605//protein targeting;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0014047//glutamate secretion;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031647//regulation of protein stability;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032467//positive regulation of cytokinesis;GO:0043542//endothelial cell migration;GO:0048023//positive regulation of melanin biosynthetic process;GO:0048167//regulation of synaptic plasticity;GO:0098761//cellular response to interleukin-7;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000123165	0	0	0	0	0	0	0	0	0	0	0	0	ACTRT1	actin related protein T1 [Source:HGNC Symbol;Acc:HGNC:24027]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003682//chromatin binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008589//regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000123171	0	0	0	0	0	0	0	0	0	0	0	0	CCDC70	coiled-coil domain containing 70 [Source:HGNC Symbol;Acc:HGNC:25303]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	GO:0005515//protein binding	-	--
ENSG00000123178	2.49	1.839	1.9	2.363	2.654	2.326	153	116	89	111	138	104	SPRYD7	SPRY domain containing 7 [Source:HGNC Symbol;Acc:HGNC:14297]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000123179	18.24	18.997	19.131	20.948	20.627	17.977	356	377	278	306	336	257	EBPL	EBP like [Source:HGNC Symbol;Acc:HGNC:18061]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0047750//cholestenol delta-isomerase activity	GO:0016125//sterol metabolic process	--
ENSG00000123191	6.49	7.022	6.869	9.05	9.516	8.818	786	863	630	838	1021	817	ATP7B	ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]	Human Diseases;Organismal Systems	Drug resistance: antineoplastic;Digestive system	ko01524//Platinum drug resistance;ko04978//Mineral absorption	K17686;K17686	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005375//copper ion transmembrane transporter activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0043682//P-type divalent copper transporter activity;GO:0046872//metal ion binding;GO:0140581//P-type monovalent copper transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006825//copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0007595//lactation;GO:0015677//copper ion import;GO:0015680//protein maturation by copper ion transfer;GO:0034220//ion transmembrane transport;GO:0035434//copper ion transmembrane transport;GO:0046688//response to copper ion;GO:0051208//sequestering of calcium ion;GO:0055070//copper ion homeostasis;GO:0060003//copper ion export;GO:0065008//regulation of biological quality;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000123200	2.562	2.468	1.408	1.193	1.33	1.655	421	403	173	147	187	192	ZC3H13	zinc finger CCCH-type containing 13 [Source:HGNC Symbol;Acc:HGNC:20368]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0080009//mRNA methylation;GO:2000036//regulation of stem cell population maintenance	--
ENSG00000123213	3.92	3.33	2.487	3.375	2.473	1.861	349	353	209	207	202	149	NLN	neurolysin [Source:HGNC Symbol;Acc:HGNC:16058]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K01393	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding	GO:0006111//regulation of gluconeogenesis;GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:1902809//regulation of skeletal muscle fiber differentiation	--
ENSG00000123219	1.453	0.743	0.462	0.581	0.416	0.876	43	26	12	11	9	13	CENPK	centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0051382//kinetochore assembly	--
ENSG00000123240	33.581	31.43	31.444	29.312	28.829	30.941	2151	2076	1465	1352	1493	1425	OPTN	optineurin [Source:HGNC Symbol;Acc:HGNC:17142]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04137//Mitophagy - animal	K19946;K19946;K19946	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031267//small GTPase binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0001920//negative regulation of receptor recycling;GO:0002376//immune system process;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0008219//cell death;GO:0010508//positive regulation of autophagy;GO:0016192//vesicle-mediated transport;GO:0034067//protein localization to Golgi apparatus;GO:0034613//cellular protein localization;GO:0034620//cellular response to unfolded protein;GO:0043001//Golgi to plasma membrane protein transport;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0090161//Golgi ribbon formation;GO:1904417//positive regulation of xenophagy	--
ENSG00000123243	51.167	51.778	54.17	65.443	70.41	74.393	4398	4317.06	3621	4472	5111	5005	ITIH5	inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process	--
ENSG00000123268	11.01	12.532	9.157	11.152	9.755	11.006	547	399	311	304	372	364	ATF1	activating transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:783]	Human Diseases;Organismal Systems	Cancer: overview;Endocrine system	ko05202//Transcriptional misregulation in cancer;ko04925//Aldosterone synthesis and secretion	K09053;K09053	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990589//ATF4-CREB1 transcription factor complex;GO:1990590//ATF1-ATF4 transcription factor complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010035//response to inorganic substance;GO:0010976//positive regulation of neuron projection development;GO:0014070//response to organic cyclic compound;GO:0014074//response to purine-containing compound;GO:0019933//cAMP-mediated signaling;GO:0032025//response to cobalt ion;GO:0034622//cellular protein-containing complex assembly;GO:0045740//positive regulation of DNA replication;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000123297	8.698	11.685	10.752	12	12.23	12.046	289.57	339	219.06	267	327	251.7	TSFM	"Ts translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12367]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding	"GO:0006412//translation;GO:0006414//translational elongation;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0070125//mitochondrial translational elongation;GO:0070129//regulation of mitochondrial translation"	--
ENSG00000123307	0	0	0	0	0	0	0	0	0	0	0	0	NEUROD4	neuronal differentiation 4 [Source:HGNC Symbol;Acc:HGNC:13802]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0010001//glial cell differentiation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0035881//amacrine cell differentiation;GO:0043010//camera-type eye development;GO:0045165//cell fate commitment;GO:0045597//positive regulation of cell differentiation;GO:0048666//neuron development;GO:0060041//retina development in camera-type eye"	bHLH
ENSG00000123329	0.506	0.468	0.513	0.635	2.287	0.501	25	20	19	23	46	20	ARHGAP9	Rho GTPase activating protein 9 [Source:HGNC Symbol;Acc:HGNC:14130]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding"	GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000123338	0.014	0	0	0	0.08	0	1	0	0	0	5	0	NCKAP1L	NCK associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:4862]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04810//Regulation of actin cytoskeleton	K05750;K05750;K05750	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0031209//SCAR complex;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0044877//protein-containing complex binding;GO:1904841//TORC2 complex binding	"GO:0000902//cell morphogenesis;GO:0001782//B cell homeostasis;GO:0002262//myeloid cell homeostasis;GO:0002687//positive regulation of leukocyte migration;GO:0006935//chemotaxis;GO:0009410//response to xenobiotic stimulus;GO:0016043//cellular component organization;GO:0016477//cell migration;GO:0030011//maintenance of cell polarity;GO:0030031//cell projection assembly;GO:0030593//neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0030866//cortical actin cytoskeleton organization;GO:0030890//positive regulation of B cell proliferation;GO:0032147//activation of protein kinase activity;GO:0032700//negative regulation of interleukin-17 production;GO:0032715//negative regulation of interleukin-6 production;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0034101//erythrocyte homeostasis;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0042102//positive regulation of T cell proliferation;GO:0042327//positive regulation of phosphorylation;GO:0043029//T cell homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043318//negative regulation of cytotoxic T cell degranulation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0045579//positive regulation of B cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045621//positive regulation of lymphocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0048812//neuron projection morphogenesis;GO:0048821//erythrocyte development;GO:0050853//B cell receptor signaling pathway;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0065003//protein-containing complex assembly;GO:0070358//actin polymerization-dependent cell motility;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1902624//positive regulation of neutrophil migration;GO:1904515//positive regulation of TORC2 signaling"	--
ENSG00000123342	0.994	1.278	1.113	1.408	1.683	1.536	69	85	57	70	95	75	MMP19	matrix metallopeptidase 19 [Source:HGNC Symbol;Acc:HGNC:7165]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001542//ovulation from ovarian follicle;GO:0001554//luteolysis;GO:0006508//proteolysis;GO:0009725//response to hormone;GO:0022617//extracellular matrix disassembly;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0051591//response to cAMP	--
ENSG00000123349	159.349	158.723	149.954	151.914	120.595	117.299	1955	1948	1366	1378	1246	1042	PFDN5	prefoldin subunit 5 [Source:HGNC Symbol;Acc:HGNC:8869]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016272//prefoldin complex;GO:0045111//intermediate filament cytoskeleton	GO:0001540//amyloid-beta binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0051082//unfolded protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006457//protein folding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0060041//retina development in camera-type eye;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1905907//negative regulation of amyloid fibril formation"	--
ENSG00000123352	10.247	10.515	7.839	7.072	7.354	8.927	641	609	371	330	370	369	SPATS2	spermatogenesis associated serine rich 2 [Source:HGNC Symbol;Acc:HGNC:18650]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000123353	14.284	15.166	18.067	13.41	14.698	16.399	392.61	399.87	342.49	263.28	326.25	305.16	ORMDL2	ORMDL sphingolipid biosynthesis regulator 2 [Source:HGNC Symbol;Acc:HGNC:16037]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035339//SPOTS complex	GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0090155//negative regulation of sphingolipid biosynthetic process;GO:0090156//cellular sphingolipid homeostasis;GO:1900060//negative regulation of ceramide biosynthetic process;GO:2000303//regulation of ceramide biosynthetic process	--
ENSG00000123358	6.248	5.592	6.561	3.834	4.727	3.75	263	252	192	107	145	111	NR4A1	nuclear receptor subfamily 4 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7980]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion	K04465;K04465;K04465;K04465;K04465	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0098793//presynapse	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035259//glucocorticoid receptor binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001938//positive regulation of endothelial cell proliferation;GO:0001975//response to amphetamine;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0014860//neurotransmitter secretion involved in regulation of skeletal muscle contraction;GO:0030522//intracellular receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0035767//endothelial cell chemotaxis;GO:0035914//skeletal muscle cell differentiation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043065//positive regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045444//fat cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050896//response to stimulus;GO:0051602//response to electrical stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0071310//cellular response to organic substance;GO:0071376//cellular response to corticotropin-releasing hormone stimulus"	NGFIB-like
ENSG00000123360	0	0.084	0.03	0.076	0.036	0	0	3	1	2	2	0	PDE1B	phosphodiesterase 1B [Source:HGNC Symbol;Acc:HGNC:8775]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Sensory system;Signal transduction;Nucleotide metabolism;Substance dependence;Sensory system;Endocrine system	ko01100//Metabolic pathways;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04742//Taste transduction;ko04924//Renin secretion	K13755;K13755;K13755;K13755;K13755;K13755;K13755	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043025//neuronal cell body	"GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0048101//calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity"	GO:0001505//regulation of neurotransmitter levels;GO:0001975//response to amphetamine;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007626//locomotory behavior;GO:0008542//visual learning;GO:0030224//monocyte differentiation;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0042053//regulation of dopamine metabolic process;GO:0042428//serotonin metabolic process;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus	--
ENSG00000123364	0	0	0	0	0.048	0	0	0	0	0	2	0	HOXC13	homeobox C13 [Source:HGNC Symbol;Acc:HGNC:5125]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0035878//nail development;GO:0043587//tongue morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000123374	18.021	15.719	17.092	13.742	15.905	18.944	779	741	567	473	594	625	CDK2	cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Signal transduction;Cell growth and death;Endocrine system;Cancer: specific types;Cancer: specific types;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05226//Gastric cancer;ko05162//Measles;ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko05215//Prostate cancer;ko05222//Small cell lung cancer;ko04115//p53 signaling pathway	K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206;K02206	"GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000781//chromosome, telomeric region;GO:0000793//condensed chromosome;GO:0000805//X chromosome;GO:0000806//Y chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015030//Cajal body;GO:0097123//cyclin A1-CDK2 complex;GO:0097124//cyclin A2-CDK2 complex;GO:0097134//cyclin E1-CDK2 complex;GO:0097135//cyclin E2-CDK2 complex"	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0030332//cyclin binding;GO:0035173//histone kinase activity;GO:0046872//metal ion binding;GO:0097472//cyclin-dependent protein kinase activity;GO:0106310//protein serine kinase activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006813//potassium ion transport;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031453//positive regulation of heterochromatin assembly;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0032298//positive regulation of DNA-dependent DNA replication initiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051298//centrosome duplication;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051726//regulation of cell cycle;GO:0071732//cellular response to nitric oxide;GO:0090398//cellular senescence;GO:1905784//regulation of anaphase-promoting complex-dependent catabolic process"	--
ENSG00000123384	63.974	69.744	61.936	48.808	58.223	51.515	19802	21699	14144	11120	15207	11593	LRP1	LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692]	Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Infectious disease: parasitic;Digestive system	ko05010//Alzheimer disease;ko05144//Malaria;ko04979//Cholesterol metabolism	K04550;K04550;K04550	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0043235//receptor complex;GO:0098797//plasma membrane protein complex	GO:0001540//amyloid-beta binding;GO:0003723//RNA binding;GO:0005041//low-density lipoprotein particle receptor activity;GO:0005044//scavenger receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016964//alpha-2 macroglobulin receptor activity;GO:0030226//apolipoprotein receptor activity;GO:0032050//clathrin heavy chain binding;GO:0034185//apolipoprotein binding;GO:0038023//signaling receptor activity;GO:0038024//cargo receptor activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0070325//lipoprotein particle receptor binding	GO:0001523//retinoid metabolic process;GO:0002265//astrocyte activation involved in immune response;GO:0006629//lipid metabolic process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006909//phagocytosis;GO:0007041//lysosomal transport;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010629//negative regulation of gene expression;GO:0010715//regulation of extracellular matrix disassembly;GO:0010875//positive regulation of cholesterol efflux;GO:0010942//positive regulation of cell death;GO:0014912//negative regulation of smooth muscle cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031623//receptor internalization;GO:0032092//positive regulation of protein binding;GO:0032370//positive regulation of lipid transport;GO:0032374//regulation of cholesterol transport;GO:0032429//regulation of phospholipase A2 activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0035909//aorta morphogenesis;GO:0042953//lipoprotein transport;GO:0043277//apoptotic cell clearance;GO:0045056//transcytosis;GO:0045807//positive regulation of endocytosis;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0097242//amyloid-beta clearance;GO:0150093//amyloid-beta clearance by transcytosis;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:0150104//transport across blood-brain barrier;GO:1900223//positive regulation of amyloid-beta clearance;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904300//positive regulation of transcytosis;GO:1904646//cellular response to amyloid-beta;GO:1905049//negative regulation of metallopeptidase activity;GO:1905167//positive regulation of lysosomal protein catabolic process;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000123388	0	0	0	0	0.028	0	0	0	0	0	1	0	HOXC11	homeobox C11 [Source:HGNC Symbol;Acc:HGNC:5123]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001656//metanephros development;GO:0001759//organ induction;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007492//endoderm development;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0042733//embryonic digit morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development;GO:0060272//embryonic skeletal joint morphogenesis"	Homeobox
ENSG00000123395	15.94	14.628	15.584	16.387	14.143	19.401	437	405	335	341	336	397	ATG101	autophagy related 101 [Source:HGNC Symbol;Acc:HGNC:25679]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Aging;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04211//Longevity regulating pathway;ko04136//Autophagy - other	K19730;K19730;K19730;K19730;K19730;K19730;K19730;K19730	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:1990316//Atg1/ULK1 kinase complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0000045//autophagosome assembly;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0008285//negative regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0046777//protein autophosphorylation;GO:1903059//regulation of protein lipidation	--
ENSG00000123405	2.983	2.881	4.196	3.939	3.308	3.201	102	99	106	92	96	80	NFE2	"nuclear factor, erythroid 2 [Source:HGNC Symbol;Acc:HGNC:7780]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0050699//WW domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006337//nucleosome disassembly;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007599//hemostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000123407	0	0	0	0	0	0	0	0	0	0	0	0	HOXC12	homeobox C12 [Source:HGNC Symbol;Acc:HGNC:5124]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000123411	4.84	4.797	4.542	3.874	4.841	4.57	488	476	325	282	416	339	IKZF4	IKAROS family zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:13179]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0032991//protein-containing complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051260//protein homooligomerization"	zf-C2H2
ENSG00000123415	11.268	9.508	10.237	16.968	13.401	15.474	271	290	214	273	287	267	SMUG1	single-strand-selective monofunctional uracil-DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:17148]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10800	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0000703//oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0004844//uracil DNA N-glycosylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0017065//single-strand selective uracil DNA N-glycosylase activity;GO:0019104//DNA N-glycosylase activity;GO:0042802//identical protein binding	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0045008//depyrimidination	--
ENSG00000123416	386.11	408.998	385.826	388.785	357.778	357.913	13030.63	13837.87	9606.22	9652.75	10190.44	8761.5	TUBA1B	tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0003725//double-stranded RNA binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031625//ubiquitin protein ligase binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0071353//cellular response to interleukin-4	--
ENSG00000123427	1.893	2.708	1.627	2.361	2.287	1.987	95.71	117	61.18	77	102	72.83	EEF1AKMT3	EEF1A lysine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:24936]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding	GO:0018022//peptidyl-lysine methylation;GO:0032259//methylation	--
ENSG00000123444	8.071	9.357	8.876	7.711	7.803	9.846	377.67	461.85	303.92	265.24	326.21	355.15	KBTBD4	kelch repeat and BTB domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23761]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000123453	3.355	3.73	3.167	3.729	4.043	2.556	222	250	156	167	216	124	SARDH	sarcosine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:10536]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism"	K00314;K00314	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0008480//sarcosine dehydrogenase activity;GO:0016491//oxidoreductase activity	GO:0008150//biological_process;GO:1901053//sarcosine catabolic process	--
ENSG00000123454	0.158	0.105	0.333	0.166	0.27	0.097	9	6	14	7	13	4	DBH	dopamine beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:2689]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K00503;K00503	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0034451//centriolar satellite;GO:0034466//chromaffin granule lumen;GO:0034774//secretory granule lumen;GO:0042584//chromaffin granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	"GO:0003824//catalytic activity;GO:0004497//monooxygenase activity;GO:0004500//dopamine beta-monooxygenase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding"	GO:0001974//blood vessel remodeling;GO:0001975//response to amphetamine;GO:0002443//leukocyte mediated immunity;GO:0006589//octopamine biosynthetic process;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0008542//visual learning;GO:0042127//regulation of cell population proliferation;GO:0042309//homoiothermy;GO:0042420//dopamine catabolic process;GO:0042421//norepinephrine biosynthetic process;GO:0042423//catecholamine biosynthetic process;GO:0042593//glucose homeostasis;GO:0042596//fear response;GO:0042711//maternal behavior;GO:0045907//positive regulation of vasoconstriction;GO:0048149//behavioral response to ethanol;GO:0048265//response to pain;GO:0050900//leukocyte migration;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000123472	39.482	43.63	46.71	39.748	39.035	44.143	1558	1692	1300	1188	1359	1268	ATPAF1	ATP synthase mitochondrial F1 complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:18803]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0065003//protein-containing complex assembly	--
ENSG00000123473	1.939	1.514	1.212	0.66	0.749	1.176	184	153	90	42	64	66	STIL	STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0120099//procentriole replication complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000578//embryonic axis specification;GO:0001701//in utero embryonic development;GO:0001843//neural tube closure;GO:0001947//heart looping;GO:0007052//mitotic spindle organization;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0021915//neural tube development;GO:0030900//forebrain development;GO:0030903//notochord development;GO:0033504//floor plate development;GO:0035264//multicellular organism growth;GO:0043066//negative regulation of apoptotic process;GO:0046599//regulation of centriole replication;GO:0046601//positive regulation of centriole replication;GO:0051298//centrosome duplication;GO:0060236//regulation of mitotic spindle organization;GO:0071539//protein localization to centrosome;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1905832//positive regulation of spindle assembly	--
ENSG00000123485	0.466	0.395	0.396	0.631	0.573	0.399	18	13	11	24	24	19	HJURP	Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0043229//intracellular organelle"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0042802//identical protein binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0034080//CENP-A containing nucleosome assembly;GO:0043254//regulation of protein-containing complex assembly;GO:0051101//regulation of DNA binding	--
ENSG00000123496	2.539	2.832	2.537	2.271	2.547	1.832	72	79	52	49	62	37	IL13RA2	interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05077;K05077	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0002638//negative regulation of immunoglobulin production;GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0043305//negative regulation of mast cell degranulation	--
ENSG00000123500	0.111	0.378	0	0	0.191	0.02	7	14	0	0	11	1	COL10A1	collagen type X alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2185]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19479	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005599//collagen type X trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization	--
ENSG00000123505	30.528	23.778	29.851	25.313	22.83	37.122	2157	1742	1572	1255	1335	1614	AMD1	adenosylmethionine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:457]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism	K01611;K01611;K01611	GO:0005829//cytosol	GO:0004014//adenosylmethionine decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0019810//putrescine binding;GO:0042802//identical protein binding	GO:0006557//S-adenosylmethioninamine biosynthetic process;GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0006597//spermine biosynthetic process;GO:0008295//spermidine biosynthetic process;GO:0046500//S-adenosylmethionine metabolic process	--
ENSG00000123545	4.827	4.364	4.421	4.678	4.86	5.423	241	219	163	173	205	197	NDUFAF4	NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18161	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0008284//positive regulation of cell population proliferation;GO:0010257//NADH dehydrogenase complex assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0043066//negative regulation of apoptotic process;GO:0051607//defense response to virus	--
ENSG00000123552	4.161	3.317	2.473	2.947	3.415	3.476	265	218	128	125	171	148	USP45	ubiquitin specific peptidase 45 [Source:HGNC Symbol;Acc:HGNC:20080]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0003407//neural retina development;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016477//cell migration;GO:0016579//protein deubiquitination;GO:0045494//photoreceptor cell maintenance;GO:0070911//global genome nucleotide-excision repair	--
ENSG00000123560	0.357	0.066	0.045	0.194	0	0	6	4	2	5	0	0	PLP1	proteolipid protein 1 [Source:HGNC Symbol;Acc:HGNC:9086]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034683//integrin alphav-beta3 complex;GO:0043209//myelin sheath;GO:0045202//synapse	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006954//inflammatory response;GO:0007268//chemical synaptic transmission;GO:0008366//axon ensheathment;GO:0010001//glial cell differentiation;GO:0010628//positive regulation of gene expression;GO:0014002//astrocyte development;GO:0021762//substantia nigra development;GO:0022010//central nervous system myelination;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0042552//myelination;GO:0042759//long-chain fatty acid biosynthetic process;GO:0061564//axon development;GO:0098990//AMPA selective glutamate receptor signaling pathway;GO:1904427//positive regulation of calcium ion transmembrane transport	--
ENSG00000123561	0	0	0	0	0	0	0	0	0	0	0	0	SERPINA7	serpin family A member 7 [Source:HGNC Symbol;Acc:HGNC:11583]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K20734	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity	GO:0010951//negative regulation of endopeptidase activity;GO:0070327//thyroid hormone transport	--
ENSG00000123562	112.162	117.512	102.198	85.318	82.887	82.693	3902	4101	2629	2243	2487	2071	MORF4L2	mortality factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:16849]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0035267//NuA4 histone acetyltransferase complex	GO:0005515//protein binding	"GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0016573//histone acetylation;GO:0016575//histone deacetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000123569	0	0	0	0	0	0	0	0	0	0	0	0	H2BW1	H2B.W histone 1 [Source:HGNC Symbol;Acc:HGNC:27252]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000123570	1.879	1.246	1.021	1.001	1.15	0.913	147	98	59	58	76	52	RAB9B	"RAB9B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14090]"	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: viral	ko05132//Salmonella infection;ko05162//Measles	K07900;K07900	GO:0005764//lysosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0042802//identical protein binding	"GO:0015031//protein transport;GO:0032482//Rab protein signal transduction;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000123572	0.507	0.552	0.115	0.176	0.205	0.093	52	49	12	20	29	11	NRK	Nik related kinase [Source:HGNC Symbol;Acc:HGNC:25391]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0048812//neuron projection morphogenesis	--
ENSG00000123575	9.979	7.971	8.194	6.642	7.2	7.483	1578	1267	957	778	962	861	FAM199X	"family with sequence similarity 199, X-linked [Source:HGNC Symbol;Acc:HGNC:25195]"	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000123576	0	0	0	0	0	0	0	0	0	0	0	0	ESX1	ESX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:14865]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18491	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle"	Homeobox
ENSG00000123584	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA9	MAGE family member A9 [Source:HGNC Symbol;Acc:HGNC:6807]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000123594	0	0	0	0	0	0	0	0	0	0	0	0	ATXN3L	ataxin 3 like [Source:HGNC Symbol;Acc:HGNC:24173]	Human Diseases;Genetic Information Processing;Human Diseases	"Neurodegenerative disease;Folding, sorting and degradation;Neurodegenerative disease"	ko05022//Pathways of neurodegeneration - multiple diseases;ko04141//Protein processing in endoplasmic reticulum;ko05017//Spinocerebellar ataxia	K11863;K11863;K11863	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination	--
ENSG00000123595	8.415	5.863	6.576	5.601	6.006	6.115	271	210	151	153	171	177	RAB9A	"RAB9A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9792]"	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: viral	ko05132//Salmonella infection;ko05162//Measles	K07899;K07899	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0042470//melanosome;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	"GO:0015031//protein transport;GO:0032482//Rab protein signal transduction;GO:0032880//regulation of protein localization;GO:0042147//retrograde transport, endosome to Golgi;GO:0045921//positive regulation of exocytosis;GO:0052403//negative regulation by host of symbiont catalytic activity"	--
ENSG00000123600	2.422	1.514	1.566	1.14	1.488	2.522	159	117	83	86	113	72	METTL8	"methyltransferase 8, methylcytidine [Source:HGNC Symbol;Acc:HGNC:25856]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004402//histone acetyltransferase activity;GO:0008168//methyltransferase activity;GO:0008174//mRNA methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0007519//skeletal muscle tissue development;GO:0016573//histone acetylation;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0045444//fat cell differentiation;GO:0080009//mRNA methylation	--
ENSG00000123607	3.161	2.114	2.456	1.58	1.811	1.937	354	234	196	138	188	171	TTC21B	tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030991//intraciliary transport particle A;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0008589//regulation of smoothened signaling pathway;GO:0010628//positive regulation of gene expression;GO:0021549//cerebellum development;GO:0021591//ventricular system development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0030900//forebrain development;GO:0035721//intraciliary retrograde transport;GO:0060020//Bergmann glial cell differentiation;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097499//protein localization to non-motile cilium;GO:1903999//negative regulation of eating behavior;GO:1905799//regulation of intraciliary retrograde transport	--
ENSG00000123609	2.818	2.576	2.381	2.956	3.018	2.147	70	66	43	54	65	38	NMI	N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0032480//negative regulation of type I interferon production;GO:0032687//negative regulation of interferon-alpha production;GO:0032688//negative regulation of interferon-beta production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045824//negative regulation of innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902524//positive regulation of protein K48-linked ubiquitination"	--
ENSG00000123610	0	0.034	0	0	0	0	0	1	0	0	0	0	TNFAIP6	TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0001968//fibronectin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0052689//carboxylic ester hydrolase activity	GO:0001550//ovarian cumulus expansion;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0030212//hyaluronan metabolic process;GO:0030335//positive regulation of cell migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0030728//ovulation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0050728//negative regulation of inflammatory response;GO:0090024//negative regulation of neutrophil chemotaxis;GO:1903911//positive regulation of receptor clustering;GO:1905590//fibronectin fibril organization	--
ENSG00000123612	0.323	0.242	0.242	0.135	0.325	0.127	25	21	12	9	23	17	ACVR1C	activin A receptor type 1C [Source:HGNC Symbol;Acc:HGNC:18123]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K13568;K13568;K13568	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0048179//activin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016361//activin receptor activity, type I;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0038100//nodal binding;GO:0046872//metal ion binding"	GO:0001834//trophectodermal cell proliferation;GO:0002021//response to dietary excess;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007399//nervous system development;GO:0009749//response to glucose;GO:0016310//phosphorylation;GO:0019915//lipid storage;GO:0030154//cell differentiation;GO:0030262//apoptotic nuclear changes;GO:0032868//response to insulin;GO:0032924//activin receptor signaling pathway;GO:0038092//nodal signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046676//negative regulation of insulin secretion;GO:0071363//cellular response to growth factor stimulus;GO:1901164//negative regulation of trophoblast cell migration;GO:1901383//negative regulation of chorionic trophoblast cell proliferation	--
ENSG00000123636	6.45	3.367	3.206	2.494	1.621	3.134	372	252	150	110	158	123	BAZ2B	bromodomain adjacent to zinc finger domain 2B [Source:HGNC Symbol;Acc:HGNC:963]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0090647//modulation of age-related behavioral decline	MBD
ENSG00000123643	5.687	5.062	5.802	7.519	7.542	7.398	671	605	513	628	703	597	SLC36A1	solute carrier family 36 member 1 [Source:HGNC Symbol;Acc:HGNC:18761]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14209	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005280//amino acid:proton symporter activity;GO:0005368//taurine transmembrane transporter activity;GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015293//symporter activity;GO:0022858//alanine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0015734//taurine transport;GO:0015804//neutral amino acid transport;GO:0015808//L-alanine transport;GO:0015816//glycine transport;GO:0015824//proline transport;GO:0032328//alanine transport;GO:0035524//proline transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000123684	17.795	14.4	15.016	14.436	14.609	16.179	2869	2324	1788	1724	1990	1898	LPGAT1	lysophosphatidylglycerol acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:28985]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K13514	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0071617//lysophospholipid acyltransferase activity	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0045723//positive regulation of fatty acid biosynthetic process	--
ENSG00000123685	0	0	0	0	0	0.079	0	0	0	0	0	1	BATF3	basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915]	Human Diseases	Cancer: overview	ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K09034	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009615//response to virus;GO:0043011//myeloid dendritic cell differentiation;GO:0097028//dendritic cell differentiation;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000123689	0	0.055	0	0	0.261	0	0	1	0	0	4	0	G0S2	G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229]	-	-	-	-	GO:0005739//mitochondrion;GO:0005811//lipid droplet	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000123700	0.357	0.17	0.508	0.413	0.416	0.502	29	16	23	26	23	36	KCNJ2	potassium inwardly rectifying channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Endocrine system;Nervous system;Digestive system;Endocrine system	ko04921//Oxytocin signaling pathway;ko04725//Cholinergic synapse;ko04971//Gastric acid secretion;ko04924//Renin secretion	K04996;K04996;K04996;K04996	GO:0005790//smooth endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body;GO:0043197//dendritic spine	"GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0042802//identical protein binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0014861//regulation of skeletal muscle contraction via regulation of action potential;GO:0015693//magnesium ion transport;GO:0030007//cellular potassium ion homeostasis;GO:0034765//regulation of ion transmembrane transport;GO:0051289//protein homotetramerization;GO:0055119//relaxation of cardiac muscle;GO:0060075//regulation of resting membrane potential;GO:0060306//regulation of membrane repolarization;GO:0071260//cellular response to mechanical stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086001//cardiac muscle cell action potential;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086011//membrane repolarization during action potential;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090076//relaxation of skeletal muscle;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000123728	4.3	4.272	4.122	3.725	3.838	4.133	341	347	246	223	262	243	RAP2C	"RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165]"	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K07839	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0044291//cell-cell contact zone;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	"GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032486//Rap protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061097//regulation of protein tyrosine kinase activity;GO:0090557//establishment of endothelial intestinal barrier"	--
ENSG00000123737	8.363	8.244	7.683	5.806	6.271	7.577	305	302	205	156	199	198	EXOSC9	exosome component 9 [Source:HGNC Symbol;Acc:HGNC:9137]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K03678	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:0101019//nucleolar exosome (RNase complex);GO:1902494//catalytic complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0006955//immune response;GO:0016075//rRNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034473//U1 snRNA 3'-end processing;GO:0034475//U4 snRNA 3'-end processing;GO:0034476//U5 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051252//regulation of RNA metabolic process;GO:0071028//nuclear mRNA surveillance;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071042//nuclear polyadenylation-dependent mRNA catabolic process"	--
ENSG00000123739	11.754	9.387	8.78	7.021	8.417	8.725	1126.78	912	702	563	713.24	646.37	PLA2G12A	phospholipase A2 group XIIA [Source:HGNC Symbol;Acc:HGNC:18554]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0008150//biological_process;GO:0016042//lipid catabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0046473//phosphatidic acid metabolic process;GO:0050482//arachidonic acid secretion	--
ENSG00000123810	3.258	2.767	3.565	3.06	2.552	2.87	68	58	55	47	44	43	B9D2	B9 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28636]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0043015//gamma-tubulin binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000123815	13.632	15.73	19.914	17.245	16.219	16.936	638	726	583	582	621	566	COQ8B	coenzyme Q8B [Source:HGNC Symbol;Acc:HGNC:19041]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016887//ATP hydrolysis activity	GO:0006744//ubiquinone biosynthetic process;GO:0016310//phosphorylation;GO:0021692//cerebellar Purkinje cell layer morphogenesis	--
ENSG00000123836	32.134	33.963	35.136	24.793	28.02	33.745	3617	3591	2895	2115	2601	2780	PFKFB2	"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Source:HGNC Symbol;Acc:HGNC:8873]"	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism	Global and overview maps;Endocrine system;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko00051//Fructose and mannose metabolism	K19029;K19029;K19029;K19029	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003873//6-phosphofructo-2-kinase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0019901//protein kinase binding"	"GO:0006000//fructose metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006007//glucose catabolic process;GO:0006089//lactate metabolic process;GO:0006090//pyruvate metabolic process;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0009749//response to glucose;GO:0016310//phosphorylation;GO:0016311//dephosphorylation;GO:0032024//positive regulation of insulin secretion;GO:0033133//positive regulation of glucokinase activity;GO:0046835//carbohydrate phosphorylation"	--
ENSG00000123838	0	0.021	0	0	0	0.029	0	1	0	0	0	1	C4BPA	complement component 4 binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1325]	Organismal Systems;Human Diseases	Immune system;Infectious disease: bacterial	ko04610//Complement and coagulation cascades;ko05133//Pertussis	K04002;K04002	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0072562//blood microparticle	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006958//complement activation, classical pathway;GO:0009609//response to symbiotic bacterium;GO:0045087//innate immune response;GO:0045732//positive regulation of protein catabolic process;GO:0045959//negative regulation of complement activation, classical pathway;GO:1903027//regulation of opsonization"	--
ENSG00000123843	0.13	0.051	0	0.271	0	0	2	1	0	4	0	0	C4BPB	complement component 4 binding protein beta [Source:HGNC Symbol;Acc:HGNC:1328]	Organismal Systems;Human Diseases	Immune system;Infectious disease: bacterial	ko04610//Complement and coagulation cascades;ko05133//Pertussis	K04003;K04003	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane	GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006958//complement activation, classical pathway;GO:0007596//blood coagulation;GO:0009609//response to symbiotic bacterium;GO:0045087//innate immune response;GO:0045732//positive regulation of protein catabolic process;GO:0045959//negative regulation of complement activation, classical pathway;GO:1903027//regulation of opsonization"	--
ENSG00000123892	32.522	35.438	36.057	38.543	36.144	43.064	966	1058	791	848	907	929	RAB38	"RAB38, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9776]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding;GO:0035650//AP-1 adaptor complex binding;GO:0035651//AP-3 adaptor complex binding;GO:0036461//BLOC-2 complex binding	GO:0006886//intracellular protein transport;GO:0007005//mitochondrion organization;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032438//melanosome organization;GO:0035646//endosome to melanosome transport;GO:0060155//platelet dense granule organization;GO:0072657//protein localization to membrane;GO:0090383//phagosome acidification;GO:1903232//melanosome assembly;GO:2001247//positive regulation of phosphatidylcholine biosynthetic process	--
ENSG00000123901	0.011	0.022	0	0.03	0.04	0.069	1	2	0	2	3	2	GPR83	G protein-coupled receptor 83 [Source:HGNC Symbol;Acc:HGNC:4523]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04210	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097730//non-motile cilium	GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0008188//neuropeptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0051384//response to glucocorticoid	--
ENSG00000123908	5.235	4.527	5.011	3.553	4.115	4.743	1329	1201	921	724	907	892	AGO2	argonaute RISC catalytic component 2 [Source:HGNC Symbol;Acc:HGNC:3263]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K11593	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005845//mRNA cap binding complex;GO:0016020//membrane;GO:0016442//RISC complex;GO:0030425//dendrite;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome;GO:0070578//RISC-loading complex;GO:1990904//ribonucleoprotein complex	"GO:0000340//RNA 7-methylguanosine cap binding;GO:0000993//RNA polymerase II complex binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0035197//siRNA binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0070551//endoribonuclease activity, cleaving siRNA-paired mRNA;GO:0090624//endoribonuclease activity, cleaving miRNA-paired mRNA;GO:0098808//mRNA cap binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0009791//post-embryonic development;GO:0010501//RNA secondary structure unwinding;GO:0010586//miRNA metabolic process;GO:0010628//positive regulation of gene expression;GO:0016246//RNA interference;GO:0030422//production of siRNA involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035087//siRNA loading onto RISC involved in RNA interference;GO:0035194//post-transcriptional gene silencing by RNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0035279//mRNA cleavage involved in gene silencing by miRNA;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045947//negative regulation of translational initiation;GO:0045975//positive regulation of translation, ncRNA-mediated;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090625//mRNA cleavage involved in gene silencing by siRNA;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901165//positive regulation of trophoblast cell migration;GO:1905618//positive regulation of miRNA mediated inhibition of translation"	--
ENSG00000123933	28.87	29.085	34.457	34.983	34.417	33.655	2258	2269	1923	2032	2282	1858	MXD4	MAX dimerization protein 4 [Source:HGNC Symbol;Acc:HGNC:13906]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	bHLH
ENSG00000123975	13.07	15.028	13.246	11.411	8.708	9.681	167	193	125	108	94	90	CKS2	CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05222//Small cell lung cancer	K02219;K02219	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0019005//SCF ubiquitin ligase complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0042393//histone binding;GO:0043130//ubiquitin binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007127//meiosis I;GO:0007346//regulation of mitotic cell cycle;GO:0008283//cell population proliferation;GO:0044772//mitotic cell cycle phase transition;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0050790//regulation of catalytic activity;GO:0051301//cell division	--
ENSG00000123977	0.527	0.171	0.543	0.116	0.305	0.236	22	6	14	3	9	6	DAW1	dynein assembly factor with WD repeats 1 [Source:HGNC Symbol;Acc:HGNC:26383]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005929//cilium;GO:0019005//SCF ubiquitin ligase complex;GO:0042995//cell projection	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0000209//protein polyubiquitination;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008150//biological_process;GO:0036158//outer dynein arm assembly;GO:0051649//establishment of localization in cell;GO:0090660//cerebrospinal fluid circulation	--
ENSG00000123983	22.492	18.834	17.194	16.611	16.645	19.819	1735	1412	954	932	1076	1085	ACSL3	acyl-CoA synthetase long chain family member 3 [Source:HGNC Symbol;Acc:HGNC:3570]	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0090433//palmitoyl-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0030182//neuron differentiation;GO:0034379//very-low-density lipoprotein particle assembly;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0044539//long-chain fatty acid import into cell;GO:0051047//positive regulation of secretion;GO:2001247//positive regulation of phosphatidylcholine biosynthetic process	--
ENSG00000123989	107.339	124.957	113.109	128.867	126.312	102.408	6637	7737	5152	5894	6575	4604	CHPF	chondroitin polymerizing factor [Source:HGNC Symbol;Acc:HGNC:24291]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00747;K00747	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000123992	18.633	20.57	20.377	26.792	21.551	17.238	553	660	447	605	552	444	DNPEP	aspartyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:2981]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0072562//blood microparticle	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process	--
ENSG00000123999	0.607	0.391	0.483	0.53	0.211	0.196	17	11	10	11	5	4	INHA	inhibin subunit alpha [Source:HGNC Symbol;Acc:HGNC:6065]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05500	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0043025//neuronal cell body;GO:0043512//inhibin A complex;GO:0043513//inhibin B complex	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0034711//inhibin binding;GO:0044877//protein-containing complex binding	GO:0001501//skeletal system development;GO:0001541//ovarian follicle development;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008584//male gonad development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0032689//negative regulation of interferon-gamma production;GO:0042127//regulation of cell population proliferation;GO:0042326//negative regulation of phosphorylation;GO:0042541//hemoglobin biosynthetic process;GO:0045578//negative regulation of B cell differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0045786//negative regulation of cell cycle;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0051726//regulation of cell cycle;GO:0060395//SMAD protein signal transduction	--
ENSG00000124003	0	0	0	0	0	0	0	0	0	0	0	0	MOGAT1	monoacylglycerol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:18210]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism	K14458;K14458	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process	--
ENSG00000124006	64.023	74.739	76.394	86.383	81.337	76.508	4331	4788	3734	4108	4699	3762	OBSL1	obscurin like cytoskeletal adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29092]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0014704//intercalated disc;GO:0030018//Z disc;GO:0031430//M band;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:1990393//3M complex	GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity	GO:0000226//microtubule cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007030//Golgi organization;GO:0007088//regulation of mitotic nuclear division;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0010842//retina layer formation;GO:0034067//protein localization to Golgi apparatus;GO:0050775//positive regulation of dendrite morphogenesis;GO:0055003//cardiac myofibril assembly	--
ENSG00000124019	0.093	0.024	0.126	0.083	0.095	0.051	5	1	5	3	4	2	FAM124B	family with sequence similarity 124 member B [Source:HGNC Symbol;Acc:HGNC:26224]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000124067	26.635	26.456	26.814	23.206	24.795	25.454	1970	2069	1586.75	1389	1612	1433	SLC12A4	solute carrier family 12 member 4 [Source:HGNC Symbol;Acc:HGNC:10913]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0007268//chemical synaptic transmission;GO:0015698//inorganic anion transport;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0140157//ammonium import across plasma membrane;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000124074	7.024	7.631	8.373	6.987	8.851	8.005	228	249	200	168	242	188	ENKD1	enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246]	-	-	-	-	GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0097546//ciliary base	GO:0005515//protein binding	-	--
ENSG00000124089	0	0	0	0	0	0	0	0	0	0	0	0	MC3R	melanocortin 3 receptor [Source:HGNC Symbol;Acc:HGNC:6931]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04201	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0042923//neuropeptide binding	"GO:0002027//regulation of heart rate;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0019222//regulation of metabolic process;GO:0032922//circadian regulation of gene expression;GO:0042309//homoiothermy;GO:0045475//locomotor rhythm;GO:0048511//rhythmic process;GO:0055078//sodium ion homeostasis;GO:0060259//regulation of feeding behavior"	--
ENSG00000124091	0	0.023	0.032	0	0	0	0	1	1	0	0	0	GCNT7	glucosaminyl (N-acetyl) transferase family member 7 [Source:HGNC Symbol;Acc:HGNC:16099]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006486//protein glycosylation	--
ENSG00000124092	0	0	0	0	0.038	0	0	0	0	0	1	0	CTCFL	CCCTC-binding factor like [Source:HGNC Symbol;Acc:HGNC:16234]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0043035//chromatin insulator sequence binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0010628//positive regulation of gene expression;GO:0016571//histone methylation;GO:0043046//DNA methylation involved in gamete generation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051569//regulation of histone H3-K4 methylation"	zf-C2H2
ENSG00000124097	0.046	0.068	0.031	0	0.027	0.063	2	3	1	0	1	2	HMGB1P1	high mobility group box 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:4993]	Organismal Systems;Cellular Processes;Cellular Processes;Genetic Information Processing	Immune system;Cell growth and death;Transport and catabolism;Replication and repair	ko04613//Neutrophil extracellular trap formation;ko04217//Necroptosis;ko04140//Autophagy - animal;ko03410//Base excision repair	K10802;K10802;K10802;K10802	GO:0005634//nucleus;GO:0005694//chromosome	"GO:0003677//DNA binding;GO:0008301//DNA binding, bending"	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000124098	37.159	32.501	33.253	27.83	27.491	27.973	2273	2024	1507	1270	1439	1261	FAM210B	family with sequence similarity 210 member B [Source:HGNC Symbol;Acc:HGNC:16102]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0043249//erythrocyte maturation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0071392//cellular response to estradiol stimulus	--
ENSG00000124102	0	0	0	0	0	0	0	0	0	0	0	0	PI3	peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0031012//extracellular matrix	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030280//structural constituent of skin epidermis;GO:0030414//peptidase inhibitor activity	GO:0007620//copulation;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0018149//peptide cross-linking;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000124103	0	0	0	0	0	0	0	0	0	0	0	0	FAM209A	family with sequence similarity 209 member A [Source:HGNC Symbol;Acc:HGNC:16100]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000124104	13.406	14.945	14.165	17.342	12.665	14.996	545.62	570.21	446.48	457.9	455.79	454.68	SNX21	sorting nexin family member 21 [Source:HGNC Symbol;Acc:HGNC:16154]	-	-	-	-	GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:1901981//phosphatidylinositol phosphate binding"	GO:0015031//protein transport	--
ENSG00000124107	0.404	0.08	0.438	1.092	1.149	1.334	5	1	4	10	12	12	SLPI	secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity	GO:0002376//immune system process;GO:0006955//immune response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0032091//negative regulation of protein binding;GO:0032496//response to lipopolysaccharide;GO:0035821//modulation of process of other organism;GO:0042742//defense response to bacterium;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response	--
ENSG00000124116	0.081	0	0.109	0	0.191	0.282	1	0	1	0	2	3	WFDC3	WAP four-disulfide core domain 3 [Source:HGNC Symbol;Acc:HGNC:15957]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response;GO:0052547//regulation of peptidase activity	--
ENSG00000124120	6.131	6.841	5.831	6.112	8.18	5.841	773	762	541	534	706	541	TTPAL	alpha tocopherol transfer protein like [Source:HGNC Symbol;Acc:HGNC:16114]	-	-	-	-	GO:0016020//membrane	GO:1902936//phosphatidylinositol bisphosphate binding	-	--
ENSG00000124126	0.498	0.698	0.599	0.694	0.625	0.442	64	92	62	72	74	45	PREX1	"phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:32594]"	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway	K12365;K12365	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019899//enzyme binding	GO:0006801//superoxide metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0030041//actin filament polymerization;GO:0030217//T cell differentiation;GO:0030593//neutrophil chemotaxis;GO:0035556//intracellular signal transduction;GO:0042119//neutrophil activation;GO:0043547//positive regulation of GTPase activity;GO:0045785//positive regulation of cell adhesion;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0072593//reactive oxygen species metabolic process;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000124134	0.021	0.097	0.029	0	0	0.015	2	11	2	0	0	1	KCNS1	potassium voltage-gated channel modifier subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:6300]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1902259//regulation of delayed rectifier potassium channel activity	--
ENSG00000124140	1.367	1.589	1.588	2.118	1.86	1.113	14	15	10	14	14	7	SLC12A5	solute carrier family 12 member 5 [Source:HGNC Symbol;Acc:HGNC:13818]	Organismal Systems	Nervous system	ko04727//GABAergic synapse	K23967	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032590//dendrite membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse;GO:0071944//cell periphery	GO:0008519//ammonium transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006821//chloride transport;GO:0006873//cellular ion homeostasis;GO:0006884//cell volume homeostasis;GO:0006971//hypotonic response;GO:0007268//chemical synaptic transmission;GO:0007612//learning;GO:0009410//response to xenobiotic stimulus;GO:0030644//cellular chloride ion homeostasis;GO:0035264//multicellular organism growth;GO:0040040//thermosensory behavior;GO:0051452//intracellular pH reduction;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0060996//dendritic spine development;GO:0071805//potassium ion transmembrane transport;GO:0072488//ammonium transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000124143	0.026	0	0	0	0	0	1	0	0	0	0	0	ARHGAP40	Rho GTPase activating protein 40 [Source:HGNC Symbol;Acc:HGNC:16226]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0030833//regulation of actin filament polymerization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000124145	29.244	31.187	29.503	31.086	29.111	29.618	1585	1699	1181	1248	1333	1168	SDC4	syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Cardiovascular disease;Signaling molecules and interaction	ko05205//Proteoglycans in cancer;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04512//ECM-receptor interaction	K16338;K16338;K16338;K16338	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043034//costamere;GO:0043202//lysosomal lumen;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0001968//fibronectin binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0070053//thrombospondin receptor activity	GO:0001657//ureteric bud development;GO:0001843//neural tube closure;GO:0010762//regulation of fibroblast migration;GO:0016477//cell migration;GO:0042060//wound healing;GO:0042130//negative regulation of T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0060122//inner ear receptor cell stereocilium organization;GO:1903543//positive regulation of exosomal secretion;GO:1903553//positive regulation of extracellular exosome assembly	--
ENSG00000124151	8.422	7.68	8.879	7.362	8.591	9.768	1382	1259	1062	892	1182	1157	NCOA3	nuclear receptor coactivator 3 [Source:HGNC Symbol;Acc:HGNC:7670]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Cancer: specific types;Endocrine system;Endocrine system;Drug resistance: antineoplastic	ko05200//Pathways in cancer;ko05224//Breast cancer;ko04915//Estrogen signaling pathway;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance	K11256;K11256;K11256;K11256;K11256	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0000993//RNA polymerase II complex binding;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0046983//protein dimerization activity;GO:0047485//protein N-terminus binding;GO:0097718//disordered domain specific binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0032870//cellular response to hormone stimulus;GO:0035624//receptor transactivation;GO:0043697//cell dedifferentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071392//cellular response to estradiol stimulus;GO:1902459//positive regulation of stem cell population maintenance;GO:2000035//regulation of stem cell division"	--
ENSG00000124155	88.392	100.296	88.056	97.374	102.011	77.885	3835	4475	2869	3179	3801	2515	PIGT	phosphatidylinositol glycan anchor biosynthesis class T [Source:HGNC Symbol;Acc:HGNC:14938]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05292;K05292	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0042765//GPI-anchor transamidase complex	GO:0005515//protein binding	GO:0006506//GPI anchor biosynthetic process;GO:0016255//attachment of GPI anchor to protein;GO:0030182//neuron differentiation;GO:0051402//neuron apoptotic process	--
ENSG00000124157	0	0	0	0	0	0	0	0	0	0	0	0	SEMG2	semenogelin 2 [Source:HGNC Symbol;Acc:HGNC:10743]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005515//protein binding;GO:0008270//zinc ion binding	GO:0019731//antibacterial humoral response;GO:0048240//sperm capacitation;GO:0050817//coagulation;GO:1900005//positive regulation of serine-type endopeptidase activity;GO:1901318//negative regulation of flagellated sperm motility	--
ENSG00000124159	0.053	0	0	0	0.031	0.109	2	0	0	0	1	3	MATN4	matrilin 4 [Source:HGNC Symbol;Acc:HGNC:6910]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix;GO:0120216//matrilin complex	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0030198//extracellular matrix organization	--
ENSG00000124160	13.65	15.029	16.531	15	15.91	17.235	882	982	757	743	873	803	NCOA5	nuclear receptor coactivator 5 [Source:HGNC Symbol;Acc:HGNC:15909]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0009966//regulation of signal transduction;GO:0042593//glucose homeostasis;GO:0046627//negative regulation of insulin receptor signaling pathway	--
ENSG00000124164	18.446	16.799	19.584	13.86	15.403	13.977	1571	1538	1147	1014	1138	893	VAPB	VAMP associated protein B and C [Source:HGNC Symbol;Acc:HGNC:12649]	Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Digestive system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04979//Cholesterol metabolism	K10707;K10707;K10707	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019899//enzyme binding;GO:0033149//FFAT motif binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity;GO:0048487//beta-tubulin binding	GO:0006874//cellular calcium ion homeostasis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006986//response to unfolded protein;GO:0007029//endoplasmic reticulum organization;GO:0019076//viral release from host cell;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036498//IRE1-mediated unfolded protein response;GO:0044790//negative regulation by host of viral release from host cell;GO:0044828//negative regulation by host of viral genome replication;GO:0044829//positive regulation by host of viral genome replication;GO:0044830//modulation by host of viral RNA genome replication;GO:0045070//positive regulation of viral genome replication;GO:0046725//negative regulation by virus of viral protein levels in host cell;GO:0061817//endoplasmic reticulum-plasma membrane tethering;GO:0090114//COPII-coated vesicle budding;GO:0090158//endoplasmic reticulum membrane organization	--
ENSG00000124171	4.569	3.687	3.992	2.615	4.304	5.007	434	352	280	184	256	346	PARD6B	par-6 family cell polarity regulator beta [Source:HGNC Symbol;Acc:HGNC:16245]	Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Infectious disease: viral;Transport and catabolism;Signal transduction;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Signal transduction	ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04391//Hippo signaling pathway - fly	K06093;K06093;K06093;K06093;K06093;K06093;K06093	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0070160//tight junction;GO:0120157//PAR polarity complex	GO:0005080//protein kinase C binding;GO:0005515//protein binding	GO:0007043//cell-cell junction assembly;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0030334//regulation of cell migration;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0051301//cell division;GO:0060341//regulation of cellular localization;GO:0065003//protein-containing complex assembly	--
ENSG00000124172	15.143	14.796	17.832	18.517	12.132	15.308	1035.99	1032.99	904.98	958.99	721.98	743.95	ATP5F1E	ATP synthase F1 subunit epsilon [Source:HGNC Symbol;Acc:HGNC:838]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02135;K02135;K02135;K02135;K02135;K02135;K02135;K02135;K02135;K02135;K02135	"GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)"	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000124177	13.35	9.222	9.106	9.117	7.017	7.313	2173	2061	1481	943	1318	1141	CHD6	chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000166//nucleotide binding;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity"	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0032508//DNA duplex unwinding;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	--
ENSG00000124181	26.498	27.612	32.353	28.517	28.957	29.384	2687	2715	2462	1965	2331	2127	PLCG1	phospholipase C gamma 1 [Source:HGNC Symbol;Acc:HGNC:9065]	Metabolism;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Environmental Information Processing;Human Diseases	Global and overview maps;Cancer: overview;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Neurodegenerative disease;Immune system;Infectious disease: bacterial;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Signal transduction;Cancer: overview;Immune system;Cancer: specific types;Immune system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Immune system;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Sensory system;Signal transduction;Immune system;Cancer: overview;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Carbohydrate metabolism;Infectious disease: bacterial;Signal transduction;Infectious disease: bacterial	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko04664//Fc epsilon RI signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05223//Non-small cell lung cancer;ko00562//Inositol phosphate metabolism;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway;ko05110//Vibrio cholerae infection"	K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116;K01116	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0008180//COP9 signalosome;GO:0030027//lamellipodium;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005168//neurotrophin TRKA receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0035254//glutamate receptor binding;GO:0046872//metal ion binding;GO:0050429//calcium-dependent phospholipase C activity	GO:0001701//in utero embryonic development;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009395//phospholipid catabolic process;GO:0010634//positive regulation of epithelial cell migration;GO:0016042//lipid catabolic process;GO:0016477//cell migration;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0046488//phosphatidylinositol metabolic process;GO:0050804//modulation of chemical synaptic transmission;GO:0050852//T cell receptor signaling pathway;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000124191	1.435	1.756	1.329	2.433	2.659	2.011	68	80	51	92	77	64	TOX2	TOX high mobility group box family member 2 [Source:HGNC Symbol;Acc:HGNC:16095]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	HMG
ENSG00000124193	31.464	30.939	30.221	24.428	29.203	32.342	2101	1963	1508	1216	1512	1422	SRSF6	serine and arginine rich splicing factor 6 [Source:HGNC Symbol;Acc:HGNC:10788]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K12893;K12893	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0036002//pre-mRNA binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010629//negative regulation of gene expression;GO:0010837//regulation of keratinocyte proliferation;GO:0032868//response to insulin;GO:0045617//negative regulation of keratinocyte differentiation;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0060548//negative regulation of cell death;GO:0061041//regulation of wound healing;GO:2000675//negative regulation of type B pancreatic cell apoptotic process"	--
ENSG00000124194	0.071	0.066	0.089	0.079	0.115	0.241	2	2	2	1	4	3	GDAP1L1	ganglioside induced differentiation associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:4213]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006749//glutathione metabolic process	--
ENSG00000124196	0	0	0	0	0	0	0	0	0	0	0	0	GTSF1L	gametocyte specific factor 1 like [Source:HGNC Symbol;Acc:HGNC:16198]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000124198	17.154	14.789	14.728	11.787	13.663	16.953	3103	2580	1988	1589	2070	2220	ARFGEF2	ADP ribosylation factor guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:15853]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18442	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005879//axonemal microtubule;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0032279//asymmetric synapse;GO:0032280//symmetric synapse;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0050811//GABA receptor binding	GO:0001881//receptor recycling;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0007032//endosome organization;GO:0010256//endomembrane system organization;GO:0015031//protein transport;GO:0032012//regulation of ARF protein signal transduction;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000124201	7.235	8.372	8.272	7.786	8.096	7.936	1062	1226	877	855	1001	851	ZNFX1	zinc finger NFX1-type containing 1 [Source:HGNC Symbol;Acc:HGNC:29271]	-	-	-	-	GO:0005634//nucleus;GO:0005741//mitochondrial outer membrane;GO:0010494//cytoplasmic stress granule;GO:0031380//nuclear RNA-directed RNA polymerase complex	GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0002218//activation of innate immune response;GO:0031048//heterochromatin assembly by small RNA;GO:0042742//defense response to bacterium;GO:0045071//negative regulation of viral genome replication;GO:0051607//defense response to virus	Others
ENSG00000124203	0	0	0	0	0	0	0	0	0	0	0	0	ZNF831	zinc finger protein 831 [Source:HGNC Symbol;Acc:HGNC:16167]	-	-	-	-	-	GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000124205	0	0.083	0	0.028	0.025	0.115	0	2	0	1	1	2	EDN3	endothelin 3 [Source:HGNC Symbol;Acc:HGNC:3178]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Circulatory system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04270//Vascular smooth muscle contraction;ko04924//Renin secretion	K05227;K05227;K05227;K05227	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0031708//endothelin B receptor binding	GO:0001755//neural crest cell migration;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007411//axon guidance;GO:0008015//blood circulation;GO:0008284//positive regulation of cell population proliferation;GO:0010460//positive regulation of heart rate;GO:0010468//regulation of gene expression;GO:0010961//cellular magnesium ion homeostasis;GO:0014826//vein smooth muscle contraction;GO:0019229//regulation of vasoconstriction;GO:0030072//peptide hormone secretion;GO:0030182//neuron differentiation;GO:0030318//melanocyte differentiation;GO:0030334//regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0031175//neuron projection development;GO:0042310//vasoconstriction;GO:0043406//positive regulation of MAP kinase activity;GO:0045597//positive regulation of cell differentiation;GO:0045840//positive regulation of mitotic nuclear division;GO:0046887//positive regulation of hormone secretion;GO:0048016//inositol phosphate-mediated signaling;GO:0048070//regulation of developmental pigmentation;GO:0048675//axon extension;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0065008//regulation of biological quality;GO:1901381//positive regulation of potassium ion transmembrane transport	--
ENSG00000124207	23.006	19.607	18.882	13.835	17.045	16.507	1693	1451	1026	754	1060	884	CSE1L	chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431]	Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Translation	ko05132//Salmonella infection;ko03013//Nucleocytoplasmic transport	K18423;K18423	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000124208	0.919	0.669	1.175	1.275	0	0	52.56	38.43	49.61	54.01	0	0	PEDS1-UBE2V1	PEDS1-UBE2V1 readthrough [Source:HGNC Symbol;Acc:HGNC:33521]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K20656;K20656	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006631//fatty acid metabolic process	--
ENSG00000124209	2.012	1.491	1.569	1.407	1.464	1.279	361	269	208	187	222	167	RAB22A	"RAB22A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9764]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07891	GO:0001726//ruffle;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0015031//protein transport;GO:0097494//regulation of vesicle size	--
ENSG00000124212	30.97	32.447	22.29	23.499	27.59	26.683	3578	3768	1902	2011	2693	2243	PTGIS	prostaglandin I2 synthase [Source:HGNC Symbol;Acc:HGNC:9603]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K01831;K01831	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008116//prostaglandin-I synthase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006690//icosanoid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0019371//cyclooxygenase pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0050728//negative regulation of inflammatory response;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0071456//cellular response to hypoxia;GO:0097190//apoptotic signaling pathway;GO:1900119//positive regulation of execution phase of apoptosis	--
ENSG00000124214	55.97	53.832	55.275	45.392	46.757	50.698	3749	3651	2736	2232	2655	2498	STAU1	staufen double-stranded RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11370]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030425//dendrite;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044297//cell body;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding	GO:0034599//cellular response to oxidative stress;GO:0045070//positive regulation of viral genome replication;GO:0046726//positive regulation by virus of viral protein levels in host cell;GO:0050804//modulation of chemical synaptic transmission;GO:0099010//modification of postsynaptic structure;GO:1900273//positive regulation of long-term synaptic potentiation	--
ENSG00000124215	0.027	0	0.014	0.052	0.05	0.014	2	0	1	2	4	1	CDH26	cadherin 26 [Source:HGNC Symbol;Acc:HGNC:15902]	-	-	-	-	GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0070097//delta-catenin binding	"GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules"	--
ENSG00000124216	0.198	0.366	0.153	0.038	0.134	0	7	13	4	1	4	0	SNAI1	snail family transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:11128]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K05707	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0001707//mesoderm formation;GO:0001837//epithelial to mesenchymal transition;GO:0003180//aortic valve morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007498//mesoderm development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0031069//hair follicle morphogenesis;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060021//roof of mouth development;GO:0060536//cartilage morphogenesis;GO:0060707//trophoblast giant cell differentiation;GO:0060806//negative regulation of cell differentiation involved in embryonic placenta development;GO:0060972//left/right pattern formation;GO:0061314//Notch signaling involved in heart development;GO:0070828//heterochromatin organization;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:2000810//regulation of bicellular tight junction assembly"	zf-C2H2
ENSG00000124217	2.047	2.098	1.951	2.686	2.255	2.372	217	223.61	152.76	211	202	183	MOCS3	molybdenum cofactor synthesis 3 [Source:HGNC Symbol;Acc:HGNC:15765]	Genetic Information Processing	"Folding, sorting and degradation"	ko04122//Sulfur relay system	K11996	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004792//thiosulfate sulfurtransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016783//sulfurtransferase activity;GO:0042292//URM1 activating enzyme activity;GO:0046872//metal ion binding;GO:0061604//molybdopterin-synthase sulfurtransferase activity;GO:0061605//molybdopterin-synthase adenylyltransferase activity	GO:0002098//tRNA wobble uridine modification;GO:0002143//tRNA wobble position uridine thiolation;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0008033//tRNA processing;GO:0008152//metabolic process;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification	--
ENSG00000124222	16.734	12.165	14.523	14.046	14.433	17.785	1286	1115	971	881	1077	1054	STX16	syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08489	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0031985//Golgi cisterna;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0048278//vesicle docking;GO:0090161//Golgi ribbon formation"	--
ENSG00000124225	27.207	29.545	21.412	13.768	19.071	15.563	2034	2068	1033	783	1088	841	PMEPA1	"prostate transmembrane protein, androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:14107]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0050699//WW domain binding;GO:0070412//R-SMAD binding	GO:0009968//negative regulation of signal transduction;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation	--
ENSG00000124226	26.247	24.309	27.708	32.478	27.644	26.373	1100	1049	837	917	886	880	RNF114	ring finger protein 114 [Source:HGNC Symbol;Acc:HGNC:13094]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation	--
ENSG00000124227	0	0	0	0	0	0	0	0	0	0	0	0	ANKRD60	ankyrin repeat domain 60 [Source:HGNC Symbol;Acc:HGNC:16217]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000124228	9.811	11.451	9.83	7.977	8.686	8.56	517	585	374	315	385	332	DDX27	DEAD-box helicase 27 [Source:HGNC Symbol;Acc:HGNC:15837]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000124232	0	0	0	0	0	0	0	0	0	0	0	0	RBPJL	recombination signal binding protein for immunoglobulin kappa J region like [Source:HGNC Symbol;Acc:HGNC:13761]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Immune system;Signal transduction	ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06053;K06053;K06053;K06053;K06053;K06053	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	CSL
ENSG00000124233	0	0	0	0	0	0	0	0	0	0	0	0	SEMG1	semenogelin 1 [Source:HGNC Symbol;Acc:HGNC:10742]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008270//zinc ion binding	GO:0007320//insemination;GO:0019731//antibacterial humoral response;GO:0031640//killing of cells of other organism;GO:0048240//sperm capacitation;GO:0050817//coagulation;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090281//negative regulation of calcium ion import;GO:1900005//positive regulation of serine-type endopeptidase activity;GO:1901318//negative regulation of flagellated sperm motility	--
ENSG00000124237	0.18	0.298	0.405	0.081	0.071	0	3	5	5	1	1	0	C20orf85	chromosome 20 open reading frame 85 [Source:HGNC Symbol;Acc:HGNC:16216]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000124243	14.316	16.791	15.438	18.157	14.553	15.461	296	357	252	307	265	268	BCAS4	breast carcinoma amplified sequence 4 [Source:HGNC Symbol;Acc:HGNC:14367]	-	-	-	-	GO:0005737//cytoplasm;GO:0031083//BLOC-1 complex	-	-	--
ENSG00000124249	0.959	0.992	0.616	1.369	0.747	1.047	50	52	23.74	52.89	32.92	39.72	KCNK15	potassium two pore domain channel subfamily K member 15 [Source:HGNC Symbol;Acc:HGNC:13814]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000124251	0.219	0.154	0.125	0.115	0.264	0.183	10.51	7.4	4.42	4.1	10.7	6.37	TP53TG5	TP53 target 5 [Source:HGNC Symbol;Acc:HGNC:15856]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0030308//negative regulation of cell growth;GO:0035556//intracellular signal transduction	--
ENSG00000124253	0	0	0	0	0	0	0	0	0	0	0	0	PCK1	phosphoenolpyruvate carboxykinase 1 [Source:HGNC Symbol;Acc:HGNC:8724]	Metabolism;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Carbohydrate metabolism;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism;Excretory system	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko04920//Adipocytokine signaling pathway;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle);ko04964//Proximal tubule bicarbonate reclamation	K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596;K01596	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004611//phosphoenolpyruvate carboxykinase activity;GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0017076//purine nucleotide binding;GO:0019003//GDP binding;GO:0030145//manganese ion binding;GO:0031406//carboxylic acid binding;GO:0046872//metal ion binding;GO:0106264//protein serine kinase activity (using GTP as donor)	GO:0006006//glucose metabolic process;GO:0006094//gluconeogenesis;GO:0006107//oxaloacetate metabolic process;GO:0006629//lipid metabolic process;GO:0007568//aging;GO:0009617//response to bacterium;GO:0014823//response to activity;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019543//propionate catabolic process;GO:0032496//response to lipopolysaccharide;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0033993//response to lipid;GO:0042593//glucose homeostasis;GO:0042594//response to starvation;GO:0043382//positive regulation of memory T cell differentiation;GO:0046327//glycerol biosynthetic process from pyruvate;GO:0046890//regulation of lipid biosynthetic process;GO:0051365//cellular response to potassium ion starvation;GO:0061402//positive regulation of transcription from RNA polymerase II promoter in response to acidic pH;GO:0070365//hepatocyte differentiation;GO:0070741//response to interleukin-6;GO:0071300//cellular response to retinoic acid;GO:0071320//cellular response to cAMP;GO:0071332//cellular response to fructose stimulus;GO:0071333//cellular response to glucose stimulus;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071377//cellular response to glucagon stimulus;GO:0071456//cellular response to hypoxia;GO:0071549//cellular response to dexamethasone stimulus;GO:1904640//response to methionine	--
ENSG00000124256	0	0	0	0	0	0	0	0	0	0	0	0	ZBP1	Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176]	Cellular Processes;Organismal Systems	Cell growth and death;Immune system	ko04217//Necroptosis;ko04623//Cytosolic DNA-sensing pathway	K12965;K12965	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003692//left-handed Z-DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0012501//programmed cell death;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060545//positive regulation of necroptotic process;GO:0070269//pyroptosis;GO:2000659//regulation of interleukin-1-mediated signaling pathway	--
ENSG00000124257	1.394	1.465	1.529	1.813	2.328	1.522	34.68	36.62	25.11	33.39	48.91	27.54	NEURL2	neuralized E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16156]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000124260	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA10	MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000124275	7.404	6.288	6.773	6.558	6.157	8.427	412	346	293	217	263	309	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:HGNC:7473]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton	"GO:0003958//NADPH-hemoprotein reductase activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0016723//oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor;GO:0030586//[methionine synthase] reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070402//NADPH binding;GO:0071949//FAD binding"	GO:0006306//DNA methylation;GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0033353//S-adenosylmethionine cycle;GO:0043418//homocysteine catabolic process;GO:0046655//folic acid metabolic process;GO:0050667//homocysteine metabolic process;GO:1904042//negative regulation of cystathionine beta-synthase activity	--
ENSG00000124279	3.062	2.026	1.859	2.899	1.996	2.032	120	79	64	61	77	74	FASTKD3	FAST kinase domains 3 [Source:HGNC Symbol;Acc:HGNC:28758]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000963//mitochondrial RNA processing;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0044528//regulation of mitochondrial mRNA stability;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000124299	51.976	49.343	55.283	55.559	55.921	58.117	2052	1961	1612	1627	1867	1671	PEPD	peptidase D [Source:HGNC Symbol;Acc:HGNC:8840]	-	-	-	-	GO:0070062//extracellular exosome	GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity;GO:0102009//proline dipeptidase activity	GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process;GO:0030574//collagen catabolic process	--
ENSG00000124302	0	0	0	0	0	0	0	0	0	0	0	0	CHST8	carbohydrate sulfotransferase 8 [Source:HGNC Symbol;Acc:HGNC:15993]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00513//Various types of N-glycan biosynthesis	K09672;K09672	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006790//sulfur compound metabolic process;GO:0007417//central nervous system development;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0042446//hormone biosynthetic process	--
ENSG00000124313	5.708	5.172	6.374	4.455	6.707	5.756	260	243	216	180	256	202	IQSEC2	IQ motif and Sec7 domain ArfGEF 2 [Source:HGNC Symbol;Acc:HGNC:29059]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12495	GO:0005737//cytoplasm;GO:0098685//Schaffer collateral - CA1 synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0050804//modulation of chemical synaptic transmission;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	--
ENSG00000124333	16.822	14.831	12.482	12.691	11.394	14.978	889	793	496	488	507	578	VAMP7	vesicle associated membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:11486]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08515	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031091//platelet alpha granule;GO:0031143//pseudopodium;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	"GO:0006887//exocytosis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0006911//phagocytosis, engulfment;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0043308//eosinophil degranulation;GO:0043312//neutrophil degranulation;GO:0043320//natural killer cell degranulation;GO:1903595//positive regulation of histamine secretion by mast cell"	--
ENSG00000124334	0	0.047	0	0	0	0.033	0	2	0	0	0	1	IL9R	interleukin 9 receptor [Source:HGNC Symbol;Acc:HGNC:6030]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05073;K05073;K05073	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004919//interleukin-9 receptor activity;GO:0005515//protein binding;GO:0019983//interleukin-9 binding	GO:0007165//signal transduction;GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0038113//interleukin-9-mediated signaling pathway;GO:0042127//regulation of cell population proliferation	--
ENSG00000124343	0.063	0	0	0.022	0.123	0.057	3	0	0	1	5	2	XG	Xg glycoprotein (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:12806]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0034109//homotypic cell-cell adhesion;GO:0072683//T cell extravasation;GO:2000391//positive regulation of neutrophil extravasation	--
ENSG00000124356	16.947	17.373	17.171	14.625	13.963	13.623	1093	1206	829	714	828	691	STAMBP	STAM binding protein [Source:HGNC Symbol;Acc:HGNC:16950]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K11866	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032154//cleavage furrow;GO:0070062//extracellular exosome	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070122//isopeptidase activity;GO:0101005//deubiquitinase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0000281//mitotic cytokinesis;GO:0006508//proteolysis;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008284//positive regulation of cell population proliferation;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016579//protein deubiquitination;GO:0043524//negative regulation of neuron apoptotic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:0070536//protein K63-linked deubiquitination	--
ENSG00000124357	19.089	20.295	23.76	27.36	19.607	21.176	550	545	466	495	469	387	NAGK	N-acetylglucosamine kinase [Source:HGNC Symbol;Acc:HGNC:17174]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K00884;K00884	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0045127//N-acetylglucosamine kinase activity	GO:0006044//N-acetylglucosamine metabolic process;GO:0006051//N-acetylmannosamine metabolic process;GO:0016310//phosphorylation;GO:0019262//N-acetylneuraminate catabolic process;GO:0046835//carbohydrate phosphorylation	--
ENSG00000124370	2.687	4.188	1.582	2.367	2.075	2.383	45	72	19	30	30	29	MCEE	methylmalonyl-CoA epimerase [Source:HGNC Symbol;Acc:HGNC:16732]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K05606;K05606;K05606;K05606;K05606	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004493//methylmalonyl-CoA epimerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0019626//short-chain fatty acid catabolic process;GO:0046491//L-methylmalonyl-CoA metabolic process	--
ENSG00000124374	1.408	1.37	1.471	1.054	1.223	1.294	184	180	142	102	135	123	PAIP2B	poly(A) binding protein interacting protein 2B [Source:HGNC Symbol;Acc:HGNC:29200]	-	-	-	-	GO:0005737//cytoplasm	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0005515//protein binding;GO:0030371//translation repressor activity"	GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0045947//negative regulation of translational initiation	--
ENSG00000124380	19.859	23.32	23.133	19.656	19.466	22.561	485	522	356	335	356	346	SNRNP27	small nuclear ribonucleoprotein U4/U6.U5 subunit 27 [Source:HGNC Symbol;Acc:HGNC:30240]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12846	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008150//biological_process;GO:0008380//RNA splicing	--
ENSG00000124383	5.831	4.796	5.2	3.229	4.25	3.577	268	218	163	101	164	118	MPHOSPH10	M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14559	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0032040//small-subunit processome;GO:0034457//Mpp10 complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0008380//RNA splicing;GO:0042254//ribosome biogenesis"	--
ENSG00000124391	0	0	0	0	0	0	0	0	0	0	0	0	IL17C	interleukin 17C [Source:HGNC Symbol;Acc:HGNC:5983]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04657//IL-17 signaling pathway	K05491;K05491	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity	GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling	--
ENSG00000124406	12.593	8.576	9.059	7.769	9.045	11.181	2117	1469	1140	955	1302	1366	ATP8A1	ATPase phospholipid transporting 8A1 [Source:HGNC Symbol;Acc:HGNC:13531]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0042584//chromaffin granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140346//phosphatidylserine flippase activity	GO:0006869//lipid transport;GO:0007612//learning;GO:0015914//phospholipid transport;GO:0030335//positive regulation of cell migration;GO:0034204//lipid translocation;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:0061092//positive regulation of phospholipid translocation;GO:0098655//cation transmembrane transport;GO:0140331//aminophospholipid translocation;GO:0150104//transport across blood-brain barrier	--
ENSG00000124422	58.677	63.255	63.011	57.891	63.598	55.887	6202	6551	4839	4473	5359	4266	USP22	ubiquitin specific peptidase 22 [Source:HGNC Symbol;Acc:HGNC:12621]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0033276//transcription factor TFTC complex	GO:0003713//transcription coactivator activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0010485//H4 histone acetyltransferase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030374//nuclear receptor coactivator activity;GO:0046872//metal ion binding	"GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0009792//embryo development ending in birth or egg hatching;GO:0016574//histone ubiquitination;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle"	--
ENSG00000124429	0	0	0	0.051	0.029	0	0	0	0	3	1	0	POF1B	POF1B actin binding protein [Source:HGNC Symbol;Acc:HGNC:13711]	-	-	-	-	GO:0005884//actin filament;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction;GO:0030057//desmosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0003382//epithelial cell morphogenesis;GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0070830//bicellular tight junction assembly	--
ENSG00000124440	6.893	7.341	8.635	9.22	8.789	8.455	492	436	434	433	474	550	HIF3A	hypoxia inducible factor 3 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15825]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0033554//cellular response to stress"	bHLH
ENSG00000124444	6.714	5.096	6.617	7.28	5.042	6.863	226	207	161	179	179	180	ZNF576	zinc finger protein 576 [Source:HGNC Symbol;Acc:HGNC:28357]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000124449	0	0	0	0	0	0	0	0	0	0	0	0	IRGC	immunity related GTPase cinema [Source:HGNC Symbol;Acc:HGNC:28835]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0006952//defense response;GO:0035458//cellular response to interferon-beta	--
ENSG00000124459	6.661	4.873	5.117	4.916	5.536	5.355	441	329	261	247	277	253	ZNF45	zinc finger protein 45 [Source:HGNC Symbol;Acc:HGNC:13111]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development"	zf-C2H2
ENSG00000124466	0.94	0.993	1.034	1.07	1.182	0.767	32	34	26	27	34	19	LYPD3	LY6/PLAUR domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24880]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0043236//laminin binding	GO:0007160//cell-matrix adhesion;GO:0034392//negative regulation of smooth muscle cell apoptotic process	--
ENSG00000124467	0	0	0	0	0	0	0	0	0	0	0	0	PSG8	pregnancy specific beta-1-glycoprotein 8 [Source:HGNC Symbol;Acc:HGNC:9525]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000124469	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM8	CEA cell adhesion molecule 8 [Source:HGNC Symbol;Acc:HGNC:1820]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000124479	0.028	0.084	0	0.151	0	0	1	3	0	4	0	0	NDP	norrin cystine knot growth factor NDP [Source:HGNC Symbol;Acc:HGNC:7678]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	"GO:0001890//placenta development;GO:0007033//vacuole organization;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0016055//Wnt signaling pathway;GO:0035426//extracellular matrix-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046697//decidualization;GO:0050896//response to stimulus;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0110135//Norrin signaling pathway"	--
ENSG00000124486	15.31	12.544	12.194	8.644	10.532	10.804	3984	3281	2344	1666	2316	2046	USP9X	ubiquitin specific peptidase 9 X-linked [Source:HGNC Symbol;Acc:HGNC:12632]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030426//growth cone;GO:0042995//cell projection	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070410//co-SMAD binding;GO:0101005//deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007292//female gamete generation;GO:0008104//protein localization;GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0030509//BMP signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0048675//axon extension;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1901537//positive regulation of DNA demethylation;GO:1904515//positive regulation of TORC2 signaling;GO:1990000//amyloid fibril formation	--
ENSG00000124490	0	0	0	0	0	0	0	0	0	0	0	0	CRISP2	cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	-	--
ENSG00000124491	0	0.025	0.034	0	0.17	0	0	2	2	0	4	0	F13A1	coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05171//Coronavirus disease - COVID-19;ko04610//Complement and coagulation cascades	K03917;K03917	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0072562//blood microparticle;GO:1990234//transferase complex	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	"GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0018149//peptide cross-linking;GO:0072378//blood coagulation, fibrin clot formation"	--
ENSG00000124493	0.046	0.019	0	0	0.126	0	3	1	0	0	7	0	GRM4	glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse;ko04742//Taste transduction	K04607;K04607;K04607;K04607	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0098793//presynapse	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008066//glutamate receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0043410//positive regulation of MAPK cascade;GO:0043523//regulation of neuron apoptotic process;GO:0051966//regulation of synaptic transmission, glutamatergic"	--
ENSG00000124496	3.281	2.776	2.817	2.646	3.131	3.019	481	404	315	289	388	315	TRERF1	transcriptional regulating factor 1 [Source:HGNC Symbol;Acc:HGNC:18273]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0033142//progesterone receptor binding;GO:0046872//metal ion binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050847//progesterone receptor signaling pathway;GO:0071393//cellular response to progesterone stimulus"	zf-C2H2
ENSG00000124507	3.015	3.245	2.604	1.625	1.731	1.67	268	290	171	107	130	108	PACSIN1	protein kinase C and casein kinase substrate in neurons 1 [Source:HGNC Symbol;Acc:HGNC:8570]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030137//COPI-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043679//axon terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098684//photoreceptor ribbon synapse;GO:0098833//presynaptic endocytic zone	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0016310//phosphorylation;GO:0030100//regulation of endocytosis;GO:0045806//negative regulation of endocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0048666//neuron development;GO:0048812//neuron projection morphogenesis;GO:0072657//protein localization to membrane;GO:0072659//protein localization to plasma membrane;GO:0097320//plasma membrane tubulation;GO:1900006//positive regulation of dendrite development	--
ENSG00000124508	14.38	14.973	14.605	13.475	16.943	14.533	826.54	827	585	554	746	594	BTN2A2	butyrophilin subfamily 2 member A2 [Source:HGNC Symbol;Acc:HGNC:1137]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0001818//negative regulation of cytokine production;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0046007//negative regulation of activated T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000124523	5.544	6.849	5.453	6.525	8.015	6.409	274	275	216	248.18	262	247	SIRT5	sirtuin 5 [Source:HGNC Symbol;Acc:HGNC:14933]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K11415;K11415	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0036054//protein-malonyllysine demalonylase activity;GO:0036055//protein-succinyllysine desuccinylase activity;GO:0046872//metal ion binding;GO:0061697//protein-glutaryllysine deglutarylase activity;GO:0070403//NAD+ binding	GO:0006471//protein ADP-ribosylation;GO:0006476//protein deacetylation;GO:0007005//mitochondrion organization;GO:0010566//regulation of ketone biosynthetic process;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0031667//response to nutrient levels;GO:0036046//protein demalonylation;GO:0036047//peptidyl-lysine demalonylation;GO:0036048//protein desuccinylation;GO:0036049//peptidyl-lysine desuccinylation;GO:0061698//protein deglutarylation;GO:0061699//peptidyl-lysine deglutarylation;GO:2000378//negative regulation of reactive oxygen species metabolic process	--
ENSG00000124532	8.518	8.264	9.322	9.011	8.988	9.99	558	504.83	446.93	401.79	454	472.94	MRS2	magnesium transporter MRS2 [Source:HGNC Symbol;Acc:HGNC:13785]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015693//magnesium ion transport;GO:0045016//mitochondrial magnesium ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000124535	21.609	22.221	22.218	24.005	23.577	23.52	955	970	741	755	893	756	WRNIP1	WRN helicase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20876]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008047//enzyme activator activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0000731//DNA synthesis involved in DNA repair;GO:0002376//immune system process;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:0045087//innate immune response;GO:0050790//regulation of catalytic activity	--
ENSG00000124541	18.651	18.449	18.634	15.596	16.252	15.347	447	449	335	278	334	274	RRP36	ribosomal RNA processing 36 [Source:HGNC Symbol;Acc:HGNC:21374]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030686//90S preribosome	GO:0003723//RNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000469//cleavage involved in rRNA processing;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis"	--
ENSG00000124557	0	0.033	0	0	0.02	0	0	2	0	0	1	0	BTN1A1	butyrophilin subfamily 1 member A1 [Source:HGNC Symbol;Acc:HGNC:1135]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001817//regulation of cytokine production;GO:0050852//T cell receptor signaling pathway	--
ENSG00000124562	51.043	48.993	50.934	53.92	54.742	60.974	826	825	629	658	771	705	SNRPC	small nuclear ribonucleoprotein polypeptide C [Source:HGNC Symbol;Acc:HGNC:11157]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11095	GO:0000243//commitment complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005685//U1 snRNP;GO:0015030//Cajal body;GO:0071004//U2-type prespliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030619//U1 snRNA binding;GO:0030627//pre-mRNA 5'-splice site binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000395//mRNA 5'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000124564	0	0	0	0	0	0	0	0	0	0	0	0	SLC17A3	solute carrier family 17 member 3 [Source:HGNC Symbol;Acc:HGNC:10931]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005436//sodium:phosphate symporter activity;GO:0008308//voltage-gated anion channel activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015136//sialic acid transmembrane transporter activity;GO:0015143//urate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0006820//anion transport;GO:0015711//organic anion transport;GO:0015739//sialic acid transport;GO:0015747//urate transport;GO:0015760//glucose-6-phosphate transport;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport;GO:1901998//toxin transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000124568	0	0	0	0	0	0	0	0	0	0	0	0	SLC17A1	solute carrier family 17 member 1 [Source:HGNC Symbol;Acc:HGNC:10929]	-	-	-	-	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005436//sodium:phosphate symporter activity;GO:0015114//phosphate ion transmembrane transporter activity;GO:0015136//sialic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0006820//anion transport;GO:0015739//sialic acid transport;GO:0015747//urate transport;GO:0035435//phosphate ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport	--
ENSG00000124570	40.114	38.254	40.657	40.913	36.272	41.808	1157	1080	852	891	869	837	SERPINB6	serpin family B member 6 [Source:HGNC Symbol;Acc:HGNC:8950]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0097180//serine protease inhibitor complex;GO:0101003//ficolin-1-rich granule membrane	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0007605//sensory perception of sound;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0071470//cellular response to osmotic stress	--
ENSG00000124571	14.328	14.086	16.003	14.865	13.417	15.109	1532	1542	1211	1105	1175	1125	XPO5	exportin 5 [Source:HGNC Symbol;Acc:HGNC:17675]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14289	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0042565//RNA nuclear export complex	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0070883//pre-miRNA binding;GO:1905172//RISC complex binding	GO:0006405//RNA export from nucleus;GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0010586//miRNA metabolic process;GO:0015031//protein transport;GO:0031047//gene silencing by RNA;GO:0035281//pre-miRNA export from nucleus;GO:0051168//nuclear export;GO:1900370//positive regulation of RNA interference	--
ENSG00000124574	4.914	4.51	7.181	4.205	4.47	4.148	327	342	280	245	338	307	ABCC10	ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05674	GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006691//leukotriene metabolic process;GO:0006869//lipid transport;GO:0015698//inorganic anion transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0071716//leukotriene transport	--
ENSG00000124575	0	0	0	0	0	0	0	0	0	0	0	0	H1-3	"H1.3 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4717]"	-	-	-	-	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006334//nucleosome assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination;GO:0080182//histone H3-K4 trimethylation;GO:0098532//histone H3-K27 trimethylation	--
ENSG00000124587	12.949	14.164	15.485	15.913	15.807	17.25	925	1017	812	841	954	892	PEX6	peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13339	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0042995//cell projection;GO:0097733//photoreceptor cell cilium	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016887//ATP hydrolysis activity;GO:0044877//protein-containing complex binding	"GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix;GO:0016561//protein import into peroxisome matrix, translocation;GO:0050821//protein stabilization"	--
ENSG00000124588	7.674	8.499	6.873	8.936	7.318	7.035	168	191	113	142	132	113	NQO2	N-ribosyldihydronicotinamide:quinone reductase 2 [Source:HGNC Symbol;Acc:HGNC:7856]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0001512//dihydronicotinamide riboside quinone reductase activity;GO:0003955//NAD(P)H dehydrogenase (quinone) activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016661//oxidoreductase activity, acting on other nitrogenous compounds as donors;GO:0031404//chloride ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0071949//FAD binding;GO:1904408//melatonin binding;GO:1905594//resveratrol binding"	GO:0022900//electron transport chain;GO:1901662//quinone catabolic process	--
ENSG00000124593	1.74	2.294	1.847	2.291	1.968	2.065	108.12	138.3	83.38	104.75	102.1	96.52	PRICKLE4	novel protein	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04511	-	-	-	--
ENSG00000124596	9.604	8.632	9.197	11.058	6.692	7.698	274	246	196	196	171	157	OARD1	O-acyl-ADP-ribose deacylase 1 [Source:HGNC Symbol;Acc:HGNC:21257]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0090734//site of DNA damage	GO:0001883//purine nucleoside binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0061463//O-acetyl-ADP-ribose deacetylase activity;GO:0140293//ADP-ribosylglutamate hydrolase activity	GO:0006974//cellular response to DNA damage stimulus;GO:0042278//purine nucleoside metabolic process;GO:0051725//protein de-ADP-ribosylation;GO:0140291//peptidyl-glutamate ADP-deribosylation	--
ENSG00000124602	0.061	0.033	0.062	0.021	0.072	0.042	4	2	3	1	4	2	UNC5CL	unc-5 family C-terminal like [Source:HGNC Symbol;Acc:HGNC:21203]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005042//netrin receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity	GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0038007//netrin-activated signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade	--
ENSG00000124608	6.089	6.588	6.939	6.918	6.494	7.057	606	659	510	510	546	511	AARS2	"alanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21022]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01872	GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004813//alanine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016597//amino acid binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006400//tRNA modification;GO:0006412//translation;GO:0006419//alanyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0070143//mitochondrial alanyl-tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000124610	0	0	0	0	0	0	0	0	0	0	0	0	H1-1	"H1.1 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4715]"	-	-	-	-	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0009986//cell surface;GO:0031982//vesicle	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination;GO:0048260//positive regulation of receptor-mediated endocytosis	--
ENSG00000124613	2.886	3.304	3.537	1.948	2.457	2.666	219	214	154	121	158	138	ZNF391	zinc finger protein 391 [Source:HGNC Symbol;Acc:HGNC:18779]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000124614	36.65	41.168	32.082	40.349	32.807	31.773	448.11	508.64	292.56	367.51	339.75	287.02	RPS10	ribosomal protein S10 [Source:HGNC Symbol;Acc:HGNC:10383]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02947;K02947	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000124615	14.544	14.443	13.968	13.468	13.312	12.38	1019.65	1018.52	718.72	683.72	799.99	625.66	MOCS1	molybdenum cofactor synthesis 1 [Source:HGNC Symbol;Acc:HGNC:7190]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K20967;K20967	GO:0005634//nucleus;GO:0005829//cytosol;GO:0019008//molybdopterin synthase complex	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0061798//GTP 3',8'-cyclase activity;GO:0061799//cyclic pyranopterin monophosphate synthase activity"	GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0032324//molybdopterin cofactor biosynthetic process	--
ENSG00000124635	0	0	0.069	0.239	0.3	0	0	0	1	2	5	0	H2BC11	H2B clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4761]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043505//CENP-A containing nucleosome	GO:0001530//lipopolysaccharide binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0019731//antibacterial humoral response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061644//protein localization to CENP-A containing chromatin;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000124641	9.025	9.561	9.499	10.375	11.055	8.895	463.87	493.94	356	395	453.81	331.99	MED20	mediator complex subunit 20 [Source:HGNC Symbol;Acc:HGNC:16840]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000124657	0	0	0	0	0	0	0	0	0	0	0	0	OR2B6	olfactory receptor family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:8241]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000124659	9.786	8.303	10.568	8.308	8.066	9.201	326	278	260	205	227	223	TBCC	tubulin folding cofactor C [Source:HGNC Symbol;Acc:HGNC:11580]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway	--
ENSG00000124664	0.404	1.13	0.07	0	0.398	0	16	45	2	0	13	0	SPDEF	SAM pointed domain containing ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:17257]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K09442	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010454//negative regulation of cell fate commitment;GO:0010455//positive regulation of cell fate commitment;GO:0030154//cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060480//lung goblet cell differentiation;GO:0060576//intestinal epithelial cell development"	ETS
ENSG00000124678	0.058	0.061	0	0.14	0	0	1	2	0	2	0	0	TCP11	t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0010737//protein kinase A signaling;GO:0030154//cell differentiation;GO:1902490//regulation of sperm capacitation	--
ENSG00000124688	12.423	12.193	12.346	14.617	11.588	14.777	327	323	240	285	259	283	MAD2L1BP	MAD2L1 binding protein [Source:HGNC Symbol;Acc:HGNC:21059]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0031965//nuclear membrane	GO:0005515//protein binding	GO:0007096//regulation of exit from mitosis;GO:1902426//deactivation of mitotic spindle assembly checkpoint	--
ENSG00000124701	0	0	0	0	0	0.041	0	0	0	0	0	1	APOBEC2	apolipoprotein B mRNA editing enzyme catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:605]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0009972//cytidine deamination;GO:0016554//cytidine to uridine editing;GO:0016556//mRNA modification;GO:0080111//DNA demethylation	--
ENSG00000124702	66.391	65.623	68.104	74.448	71.631	72.323	2576	2559	1952	2140	2349	2042	KLHDC3	kelch domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20704]	-	-	-	-	GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0007131//reciprocal meiotic recombination;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051321//meiotic cell cycle;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000124713	0.045	0.045	0.364	0.181	0.159	0.123	1	1	6	3	3	2	GNMT	glycine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:4415]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism"	K00552;K00552	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016594//glycine binding;GO:0016740//transferase activity;GO:0017174//glycine N-methyltransferase activity;GO:0042802//identical protein binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0005977//glycogen metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006464//cellular protein modification process;GO:0006555//methionine metabolic process;GO:0006730//one-carbon metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0032259//methylation;GO:0046498//S-adenosylhomocysteine metabolic process;GO:0046500//S-adenosylmethionine metabolic process;GO:0051289//protein homotetramerization;GO:1901052//sarcosine metabolic process	--
ENSG00000124721	0	0.004	0.01	0	0	0	0	1	2	0	0	0	DNAH8	dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement;GO:0036158//outer dynein arm assembly;GO:0060285//cilium-dependent cell motility	--
ENSG00000124731	0.062	0.062	0	0	0.104	0.02	1	1	0	0	2	1	TREM1	triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0038023//signaling receptor activity;GO:0097110//scaffold protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002526//acute inflammatory response;GO:0006959//humoral immune response;GO:0030593//neutrophil chemotaxis;GO:0035556//intracellular signal transduction;GO:0045087//innate immune response;GO:0070945//neutrophil-mediated killing of gram-negative bacterium	--
ENSG00000124733	41.929	49.196	43.338	39.963	37.373	36.871	917.51	1105.43	729.23	645.01	706.27	587.74	MEA1	male-enhanced antigen 1 [Source:HGNC Symbol;Acc:HGNC:6986]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0030154//cell differentiation	--
ENSG00000124743	0.643	0.739	0.663	0.338	0.484	0.48	77	89	55	30	49	41	KLHL31	kelch like family member 31 [Source:HGNC Symbol;Acc:HGNC:21353]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0001933//negative regulation of protein phosphorylation;GO:0046329//negative regulation of JNK cascade	--
ENSG00000124749	0.578	0.676	0.297	0.281	0.343	0.495	45	44	19	18	23	27	COL21A1	collagen type XXI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:17025]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K16629	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0062023//collagen-containing extracellular matrix	GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0030199//collagen fibril organization	--
ENSG00000124762	6.528	7.047	5.522	2.921	2.911	2.074	287	312	179	95	108	67	CDKN1A	cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Signal transduction;Cell growth and death;Signal transduction;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04066//HIF-1 signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625;K06625	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0070557//PCNA-p21 complex	GO:0004860//protein kinase inhibitor activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0019912//cyclin-dependent protein kinase activating kinase activity;GO:0030332//cyclin binding;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0140311//protein sequestering activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006606//protein import into nucleus;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007265//Ras protein signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0009411//response to UV;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0030890//positive regulation of B cell proliferation;GO:0031668//cellular response to extracellular stimulus;GO:0032091//negative regulation of protein binding;GO:0034198//cellular response to amino acid starvation;GO:0042060//wound healing;GO:0042246//tissue regeneration;GO:0042326//negative regulation of phosphorylation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043068//positive regulation of programmed cell death;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0048146//positive regulation of fibroblast proliferation;GO:0051726//regulation of cell cycle;GO:0060255//regulation of macromolecule metabolic process;GO:0071479//cellular response to ionizing radiation;GO:0071480//cellular response to gamma radiation;GO:0071493//cellular response to UV-B;GO:0072331//signal transduction by p53 class mediator;GO:0090398//cellular senescence;GO:0090399//replicative senescence;GO:0090400//stress-induced premature senescence;GO:0097193//intrinsic apoptotic signaling pathway;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1904030//negative regulation of cyclin-dependent protein kinase activity;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1905179//negative regulation of cardiac muscle tissue regeneration;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000278//regulation of DNA biosynthetic process;GO:2000279//negative regulation of DNA biosynthetic process;GO:2000379//positive regulation of reactive oxygen species metabolic process"	--
ENSG00000124766	38.953	37.345	33.289	20.626	23.979	20.848	3934	3791	2483	1543	2046	1532	SOX4	SRY-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11200]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K23581	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001841//neural tube formation;GO:0002328//pro-B cell differentiation;GO:0003183//mitral valve morphogenesis;GO:0003211//cardiac ventricle formation;GO:0003215//cardiac right ventricle morphogenesis;GO:0003289//atrial septum primum morphogenesis;GO:0003357//noradrenergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0014009//glial cell proliferation;GO:0021510//spinal cord development;GO:0021522//spinal cord motor neuron differentiation;GO:0021782//glial cell development;GO:0030154//cell differentiation;GO:0030217//T cell differentiation;GO:0031018//endocrine pancreas development;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032024//positive regulation of insulin secretion;GO:0035019//somatic stem cell population maintenance;GO:0035910//ascending aorta morphogenesis;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045727//positive regulation of translation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048485//sympathetic nervous system development;GO:0050821//protein stabilization;GO:0060174//limb bud formation;GO:0060412//ventricular septum morphogenesis;GO:0060548//negative regulation of cell death;GO:0060563//neuroepithelial cell differentiation;GO:0060993//kidney morphogenesis;GO:0061484//hematopoietic stem cell homeostasis;GO:0071333//cellular response to glucose stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000761//positive regulation of N-terminal peptidyl-lysine acetylation"	HMG
ENSG00000124767	57.992	59.385	59.773	53.496	52.253	54.494	2425	2496	1846	1657	1846	1658	GLO1	glyoxalase I [Source:HGNC Symbol;Acc:HGNC:4323]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K01759;K01759	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0004462//lactoylglutathione lyase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006749//glutathione metabolic process;GO:0009438//methylglyoxal metabolic process;GO:0030316//osteoclast differentiation;GO:0043066//negative regulation of apoptotic process	--
ENSG00000124772	3.118	3.261	3.164	4.383	4.984	4.243	159	147	125	162	190	152	CPNE5	copine 5 [Source:HGNC Symbol;Acc:HGNC:2318]	-	-	-	-	GO:0005886//plasma membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0030154//cell differentiation;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000124780	0	0	0	0	0	0	0	0	0	0	0	0	KCNK17	potassium two pore domain channel subfamily K member 17 [Source:HGNC Symbol;Acc:HGNC:14465]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000124782	5.047	4.674	5.198	4.852	6.118	5.912	545	622	436	437	587	463	RREB1	ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K20210	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0070062//extracellular exosome	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007265//Ras protein signal transduction;GO:0007275//multicellular organism development;GO:0010634//positive regulation of epithelial cell migration;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090336//positive regulation of brown fat cell differentiation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1903691//positive regulation of wound healing, spreading of epidermal cells;GO:2000394//positive regulation of lamellipodium morphogenesis"	zf-C2H2
ENSG00000124783	94.864	88.575	89.605	77.19	81.563	82.026	5481	5109	3769	3192	3887	3313	SSR1	signal sequence receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:11323]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13249	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006613//cotranslational protein targeting to membrane;GO:0008284//positive regulation of cell population proliferation	--
ENSG00000124784	4.3	3.273	5.114	3.291	2.869	3.399	186	160	148	121	122	111	RIOK1	RIO kinase 1 [Source:HGNC Symbol;Acc:HGNC:18656]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K07178	"GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor;GO:0034708//methyltransferase complex"	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis;GO:2000234//positive regulation of rRNA processing	--
ENSG00000124785	0.417	0.091	0.126	0.711	0.22	0.209	14	3	3	17	6	5	NRN1	neuritin 1 [Source:HGNC Symbol;Acc:HGNC:17972]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0045202//synapse;GO:0046658//anchored component of plasma membrane	-	GO:0007399//nervous system development;GO:1990138//neuron projection extension	--
ENSG00000124786	7.908	6.643	6.853	5.383	5.607	5.944	354	310	225	184	234	199	SLC35B3	solute carrier family 35 member B3 [Source:HGNC Symbol;Acc:HGNC:21601]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0022857//transmembrane transporter activity;GO:0046964//3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0055085//transmembrane transport;GO:1902559//3'-phospho-5'-adenylyl sulfate transmembrane transport	--
ENSG00000124787	1.626	2.604	2.071	1.448	2.735	2.389	44	60	34	27	52	38	RPP40	ribonuclease P/MRP subunit p40 [Source:HGNC Symbol;Acc:HGNC:20992]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14530	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030677//ribonuclease P complex;GO:0030681//multimeric ribonuclease P complex	GO:0000171//ribonuclease MRP activity;GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing;GO:1905267//endonucleolytic cleavage involved in tRNA processing"	--
ENSG00000124788	4.685	3.768	3.419	2.736	4.272	5.281	783	687	553	425	654	438	ATXN1	ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548]	Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05017//Spinocerebellar ataxia;ko04330//Notch signaling pathway	K23616;K23616;K23616	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0042405//nuclear inclusion body	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008266//poly(U) RNA binding;GO:0034046//poly(G) binding;GO:0042802//identical protein binding;GO:0043621//protein self-association	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006396//RNA processing;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007612//learning;GO:0007613//memory;GO:0035176//social behavior;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048856//anatomical structure development;GO:0051168//nuclear export"	--
ENSG00000124789	11.369	10.045	10.627	9.105	9.195	10.193	1421	1262	981	843	971	927	NUP153	nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14296;K14296	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0042405//nuclear inclusion body;GO:0043657//host cell;GO:0044615//nuclear pore nuclear basket	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore;GO:0042802//identical protein binding;GO:0043495//protein-membrane adaptor activity;GO:0046872//metal ion binding	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0046718//viral entry into host cell;GO:0046832//negative regulation of RNA export from nucleus;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly;GO:0075732//viral penetration into host nucleus	--
ENSG00000124795	24.434	18.934	20.042	12.959	16.563	20	1292	1023	736	547	710	734	DEK	DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043292//contractile fiber;GO:0110016//B-WICH complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0019079//viral genome replication;GO:0035066//positive regulation of histone acetylation;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:2000779//regulation of double-strand break repair;GO:2001032//regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000124802	7.318	8.023	7.123	7.285	7.403	9.757	147	162	100	102	117	140	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1 [Source:HGNC Symbol;Acc:HGNC:3212]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	GO:0005515//protein binding	"GO:0006412//translation;GO:0008285//negative regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000774//positive regulation of cellular senescence;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000124812	0	0	0	0	0	0	0	0	0	0	0	0	CRISP1	cysteine rich secretory protein 1 [Source:HGNC Symbol;Acc:HGNC:304]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus	GO:0005246//calcium channel regulator activity	GO:0007339//binding of sperm to zona pellucida;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0060046//regulation of acrosome reaction	--
ENSG00000124813	0.191	0.125	0.127	0	0.127	0.069	15	14	9	0	5	3	RUNX2	RUNX family transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10472]	Human Diseases;Organismal Systems	Cancer: overview;Endocrine system	"ko05202//Transcriptional misregulation in cancer;ko04928//Parathyroid hormone synthesis, secretion and action"	K09278;K09278	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0031490//chromatin DNA binding;GO:0043425//bHLH transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0002051//osteoblast fate commitment;GO:0002062//chondrocyte differentiation;GO:0002063//chondrocyte development;GO:0002076//osteoblast development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0030278//regulation of ossification;GO:0030509//BMP signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0033591//response to L-ascorbic acid;GO:0035115//embryonic forelimb morphogenesis;GO:0036076//ligamentous ossification;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0045595//regulation of cell differentiation;GO:0045667//regulation of osteoblast differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048863//stem cell differentiation;GO:0051094//positive regulation of developmental process;GO:0071773//cellular response to BMP stimulus;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1904383//response to sodium phosphate"	Runt
ENSG00000124818	0	0	0	0	0	0	0	0	0	0	0	0	OPN5	opsin 5 [Source:HGNC Symbol;Acc:HGNC:19992]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005502//11-cis retinal binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007604//phototransduction, UV;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0043153//entrainment of circadian clock by photoperiod;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus;GO:0071492//cellular response to UV-A;GO:1990384//hyaloid vascular plexus regression"	--
ENSG00000124827	0	0	0	0	0	0	0	0	0	0	0	0	GCM2	glial cells missing transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:4198]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K21598	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006874//cellular calcium ion homeostasis;GO:0030643//cellular phosphate ion homeostasis;GO:0042063//gliogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060017//parathyroid gland development"	GCM
ENSG00000124831	12.167	10.141	8.836	5.459	7.729	9.613	946	792	516	319.97	514.97	545.98	LRRFIP1	LRR binding FLII interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6702]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	LRRFIP
ENSG00000124839	10.793	9.406	8.961	11.467	10.379	14.838	308	308	221	277	285	321	RAB17	"RAB17, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16523]"	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0030425//dendrite;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0032401//establishment of melanosome localization;GO:0032402//melanosome transport;GO:0032456//endocytic recycling;GO:0045056//transcytosis;GO:0046847//filopodium assembly;GO:0050773//regulation of dendrite development;GO:0051489//regulation of filopodium assembly;GO:0051963//regulation of synapse assembly;GO:0060271//cilium assembly	--
ENSG00000124875	0.596	0.946	0.425	0.375	0.149	0.517	19	27	10	6	4	12	CXCL6	C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643]	Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Immune disease;Signal transduction;Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko05323//Rheumatoid arthritis;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05133//Pertussis	K05506;K05506;K05506;K05506;K05506;K05506;K05506	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0045236//CXCR chemokine receptor binding	GO:0001776//leukocyte homeostasis;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009605//response to external stimulus;GO:0030593//neutrophil chemotaxis;GO:0032496//response to lipopolysaccharide;GO:0032642//regulation of chemokine production;GO:0042119//neutrophil activation;GO:0042742//defense response to bacterium;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0070951//regulation of neutrophil mediated killing of gram-negative bacterium;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000124882	0.084	0.083	0.042	0.028	0.049	0.086	8	8	3	2	4	6	EREG	epiregulin [Source:HGNC Symbol;Acc:HGNC:3443]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Cancer: specific types;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway	K09784;K09784;K09784;K09784	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0001525//angiogenesis;GO:0001550//ovarian cumulus expansion;GO:0001556//oocyte maturation;GO:0001819//positive regulation of cytokine production;GO:0007143//female meiotic nuclear division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009299//mRNA transcription;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030728//ovulation;GO:0032755//positive regulation of interleukin-6 production;GO:0042060//wound healing;GO:0042327//positive regulation of phosphorylation;GO:0042700//luteinizing hormone signaling pathway;GO:0043434//response to peptide hormone;GO:0043616//keratinocyte proliferation;GO:0045089//positive regulation of innate immune response;GO:0045740//positive regulation of DNA replication;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048146//positive regulation of fibroblast proliferation;GO:0048160//primary follicle stage;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0051781//positive regulation of cell division"	--
ENSG00000124900	0	0	0	0	0	0	0	0	0	0	0	0	TRIM51	tripartite motif-containing 51 [Source:HGNC Symbol;Acc:HGNC:19023]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000124920	199.225	211.218	237.598	295.076	286.982	293.885	22673	24387	19952	24897	28062	24542	MYRF	myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0014003//oligodendrocyte development;GO:0016540//protein autoprocessing;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0031643//positive regulation of myelination;GO:0032286//central nervous system myelin maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048709//oligodendrocyte differentiation"	NDT80/PhoG
ENSG00000124935	1.06	0.211	1.148	0.143	3.01	0.146	10	2	8	1	24	1	SCGB1D2	secretoglobin family 1D member 2 [Source:HGNC Symbol;Acc:HGNC:18396]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	-	--
ENSG00000124939	0	0	0	0	0.11	0	0	0	0	0	1	0	SCGB2A1	secretoglobin family 2A member 1 [Source:HGNC Symbol;Acc:HGNC:7051]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0030521//androgen receptor signaling pathway	--
ENSG00000124942	48.212	48.74	49.938	46.458	48.764	40.9	17733	17911	14045	12373	15107	11278	AHNAK	AHNAK nucleoprotein [Source:HGNC Symbol;Acc:HGNC:347]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23934	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030315//T-tubule;GO:0031982//vesicle;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0044291//cell-cell contact zone;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0098797//plasma membrane protein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0045296//cadherin binding;GO:0097493//structural molecule activity conferring elasticity	GO:0043484//regulation of RNA splicing;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1905686//positive regulation of plasma membrane repair	--
ENSG00000125037	28.025	26.818	31.141	26.336	25.09	30.129	1011	959	823	692	744	771	EMC3	ER membrane protein complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:23999]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000125046	0.089	0	0	0.218	0.095	0.04	3	0	0	6	3	1	SSUH2	ssu-2 homolog [Source:HGNC Symbol;Acc:HGNC:24809]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding	GO:0042476//odontogenesis	--
ENSG00000125084	0	0	0	0	0	0	0	0	0	0	0	0	WNT1	Wnt family member 1 [Source:HGNC Symbol;Acc:HGNC:12774]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209;K03209	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0016015//morphogen activity;GO:0019904//protein domain specific binding;GO:0048018//receptor ligand activity	"GO:0000578//embryonic axis specification;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007520//myoblast fusion;GO:0008284//positive regulation of cell population proliferation;GO:0009611//response to wounding;GO:0010592//positive regulation of lamellipodium assembly;GO:0010812//negative regulation of cell-substrate adhesion;GO:0014902//myotube differentiation;GO:0016055//Wnt signaling pathway;GO:0021527//spinal cord association neuron differentiation;GO:0021536//diencephalon development;GO:0021549//cerebellum development;GO:0021551//central nervous system morphogenesis;GO:0021588//cerebellum formation;GO:0021797//forebrain anterior/posterior pattern specification;GO:0022004//midbrain-hindbrain boundary maturation during brain development;GO:0022008//neurogenesis;GO:0022037//metencephalon development;GO:0022408//negative regulation of cell-cell adhesion;GO:0030182//neuron differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030901//midbrain development;GO:0030917//midbrain-hindbrain boundary development;GO:0031100//animal organ regeneration;GO:0033077//T cell differentiation in thymus;GO:0033278//cell proliferation in midbrain;GO:0036520//astrocyte-dopaminergic neuron signaling;GO:0042472//inner ear morphogenesis;GO:0042770//signal transduction in response to DNA damage;GO:0043066//negative regulation of apoptotic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0048663//neuron fate commitment;GO:0048664//neuron fate determination;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060061//Spemann organizer formation;GO:0060070//canonical Wnt signaling pathway;GO:0060348//bone development;GO:0061184//positive regulation of dermatome development;GO:0070365//hepatocyte differentiation;GO:0071375//cellular response to peptide hormone stimulus;GO:0071425//hematopoietic stem cell proliferation;GO:0071542//dopaminergic neuron differentiation;GO:0090344//negative regulation of cell aging;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1990403//embryonic brain development;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000125089	2.734	2.25	2.378	4.439	4.009	4.344	176	141	152	230	216	199	SH3TC1	SH3 domain and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:26009]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000125107	37.924	33.832	34.592	29.619	31.397	38.988	4840.57	4624.78	3398.26	2970.3	3510.81	3357.6	CNOT1	CCR4-NOT transcription complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7877]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12604	GO:0000932//P-body;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex	GO:0003723//RNA binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030331//estrogen receptor binding;GO:0042974//retinoic acid receptor binding;GO:0060090//molecular adaptor activity;GO:0070016//armadillo repeat domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001829//trophectodermal cell differentiation;GO:0006417//regulation of translation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0017148//negative regulation of translation;GO:0031047//gene silencing by RNA;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035195//gene silencing by miRNA;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0061014//positive regulation of mRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2000036//regulation of stem cell population maintenance"	--
ENSG00000125124	15.956	14.62	16.683	13.694	15.199	16.491	911	856	699	591	752	712.05	BBS2	Bardet-Biedl syndrome 2 [Source:HGNC Symbol;Acc:HGNC:967]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0031514//motile cilium;GO:0034464//BBSome;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0060170//ciliary membrane	GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0007288//sperm axoneme assembly;GO:0007601//visual perception;GO:0008104//protein localization;GO:0015031//protein transport;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030030//cell projection organization;GO:0030534//adult behavior;GO:0032402//melanosome transport;GO:0033365//protein localization to organelle;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0043001//Golgi to plasma membrane protein transport;GO:0045444//fat cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0048854//brain morphogenesis;GO:0050896//response to stimulus;GO:0060271//cilium assembly;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:1905515//non-motile cilium assembly	--
ENSG00000125144	2.476	1.769	1.921	1.113	2.658	2.927	21	15	12	7	19	18	MT1G	metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0030224//monocyte differentiation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042117//monocyte activation;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000125148	17.914	19.497	17.418	23.86	17.788	24.596	149	163	107	147	125	149	MT2A	metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006878//cellular copper ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0036016//cellular response to interleukin-3;GO:0036018//cellular response to erythropoietin;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000125149	6.419	5.864	6.893	7.197	5.792	7.124	301.3	329.92	262.96	270.57	275.48	277.26	PHAF1	phagosome assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:29564]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane	GO:0005515//protein binding	GO:0043001//Golgi to plasma membrane protein transport	--
ENSG00000125166	169.304	173.587	201.534	209.498	198.497	200.688	8466	8711	7415	7748	8360	7298	GOT2	glutamic-oxaloacetic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4433]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Digestive system;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism;ko04975//Fat digestion and absorption;ko00250//Alanine, aspartate and glutamate metabolism;ko00350//Tyrosine metabolism;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism;ko00360//Phenylalanine metabolism;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K14455;K14455;K14455;K14455;K14455;K14455;K14455;K14455;K14455;K14455;K14455;K14455	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006103//2-oxoglutarate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0006531//aspartate metabolic process;GO:0006532//aspartate biosynthetic process;GO:0006533//aspartate catabolic process;GO:0006536//glutamate metabolic process;GO:0006869//lipid transport;GO:0009058//biosynthetic process;GO:0015908//fatty acid transport;GO:0019470//4-hydroxyproline catabolic process;GO:0019550//glutamate catabolic process to aspartate;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0045471//response to ethanol;GO:0097052//L-kynurenine metabolic process	--
ENSG00000125170	23.667	24.241	22.132	24.42	20.883	24.63	1131	1137	847	782	900	848	DOK4	docking protein 4 [Source:HGNC Symbol;Acc:HGNC:19868]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000125207	0	0	0	0	0	0	0	0	0	0	0	0	PIWIL1	piwi like RNA-mediated gene silencing 1 [Source:HGNC Symbol;Acc:HGNC:9007]	Organismal Systems	Development and regeneration	ko04320//Dorso-ventral axis formation	K02156	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0097433//dense body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0034584//piRNA binding;GO:0046872//metal ion binding;GO:0061980//regulatory RNA binding;GO:0140262//mRNA cap binding complex binding;GO:1905538//polysome binding	"GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000125245	0	0	0	0	0.041	0	0	0	0	0	1	0	GPR18	G protein-coupled receptor 18 [Source:HGNC Symbol;Acc:HGNC:4472]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0004930//G protein-coupled receptor activity	"GO:0002300//CD8-positive, alpha-beta intraepithelial T cell differentiation;GO:0002305//CD8-positive, gamma-delta intraepithelial T cell differentiation;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway"	--
ENSG00000125246	8.704	9.22	9.568	9.845	7.877	6.431	247	285	222	228	230	161	CLYBL	citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004474//malate synthase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0047777//(S)-citramalyl-CoA lyase activity	GO:0070207//protein homotrimerization;GO:0106064//regulation of cobalamin metabolic process;GO:0106121//positive regulation of cobalamin metabolic process	--
ENSG00000125247	7.651	8.271	6.949	5.972	7.143	7.219	563	542	387	312	435	342	TMTC4	transmembrane O-mannosyltransferase targeting cadherins 4 [Source:HGNC Symbol;Acc:HGNC:25904]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0051117//ATPase binding	GO:0006486//protein glycosylation;GO:0007605//sensory perception of sound;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032470//positive regulation of endoplasmic reticulum calcium ion concentration;GO:0035269//protein O-linked mannosylation;GO:1905584//outer hair cell apoptotic process	--
ENSG00000125249	14.994	12.718	11.488	10.703	11.413	13.383	1723	1469	975	911	1108	1108	RAP2A	"RAP2A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9861]"	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0030033//microvillus assembly;GO:0030336//negative regulation of cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0031954//positive regulation of protein autophosphorylation;GO:0032486//Rap protein signal transduction;GO:0034613//cellular protein localization;GO:0045184//establishment of protein localization;GO:0046328//regulation of JNK cascade;GO:0048814//regulation of dendrite morphogenesis;GO:0071466//cellular response to xenobiotic stimulus;GO:0072659//protein localization to plasma membrane	--
ENSG00000125255	0	0	0	0	0	0	0	0	0	0	0	0	SLC10A2	solute carrier family 10 member 2 [Source:HGNC Symbol;Acc:HGNC:10906]	Organismal Systems	Digestive system	ko04976//Bile secretion	K14342	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding;GO:0008508//bile acid:sodium symporter activity;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0009617//response to bacterium;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport	--
ENSG00000125257	28.264	25.718	26.192	17.962	18.558	25.68	3331	3012	2257	1579	1813	2183	ABCC4	ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Digestive system;Membrane transport;Drug resistance: antineoplastic	ko04024//cAMP signaling pathway;ko04976//Bile secretion;ko02010//ABC transporters;ko01523//Antifolate resistance	K05673;K05673;K05673;K05673	GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031088//platelet dense granule membrane;GO:0098591//external side of apical plasma membrane	GO:0000166//nucleotide binding;GO:0001409//guanine nucleotide transmembrane transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0015132//prostaglandin transmembrane transporter activity;GO:0015143//urate transmembrane transporter activity;GO:0015216//purine nucleotide transmembrane transporter activity;GO:0015431//ABC-type glutathione S-conjugate transporter activity;GO:0015432//ABC-type bile acid transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0016404//15-hydroxyprostaglandin dehydrogenase (NAD+) activity;GO:0034634//glutathione transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0043225//ATPase-coupled inorganic anion transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0002576//platelet degranulation;GO:0006869//lipid transport;GO:0015698//inorganic anion transport;GO:0015721//bile acid and bile salt transport;GO:0015732//prostaglandin transport;GO:0015747//urate transport;GO:0032310//prostaglandin secretion;GO:0034775//glutathione transmembrane transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0060271//cilium assembly;GO:0070730//cAMP transport;GO:0071716//leukotriene transport;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903790//guanine nucleotide transmembrane transport	--
ENSG00000125266	10.598	8.479	8.534	7.388	7.346	10.121	1098	883	653	567	643	763	EFNB2	ephrin B2 [Source:HGNC Symbol;Acc:HGNC:3227]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05463	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0001618//virus receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0001525//angiogenesis;GO:0001945//lymph vessel development;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010839//negative regulation of keratinocyte proliferation;GO:0010977//negative regulation of neuron projection development;GO:0030154//cell differentiation;GO:0031295//T cell costimulation;GO:0034332//adherens junction organization;GO:0046718//viral entry into host cell;GO:0048013//ephrin receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0048845//venous blood vessel morphogenesis;GO:0050920//regulation of chemotaxis;GO:0071222//cellular response to lipopolysaccharide;GO:0072178//nephric duct morphogenesis;GO:0099054//presynapse assembly;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1901216//positive regulation of neuron death;GO:1903849//positive regulation of aorta morphogenesis;GO:2000727//positive regulation of cardiac muscle cell differentiation	--
ENSG00000125285	0	0	0	0	0	0	0	0	0	0	0	0	SOX21	SRY-box transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11197]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0042633//hair cycle;GO:0043588//skin development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048863//stem cell differentiation"	HMG
ENSG00000125304	100.703	99.398	96.542	96.963	92.65	103.897	7211	7160	5112	5134	5630	5419	TM9SF2	transmembrane 9 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11865]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	-	GO:0006672//ceramide metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0010908//regulation of heparan sulfate proteoglycan biosynthetic process;GO:0072657//protein localization to membrane	--
ENSG00000125319	0.375	0.596	0.556	0.314	0.399	0.344	21	33	23	13	19	14	HROB	homologous recombination factor with OB-fold [Source:HGNC Symbol;Acc:HGNC:28460]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0090734//site of DNA damage	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0000725//recombinational repair;GO:0000731//DNA synthesis involved in DNA repair;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007292//female gamete generation;GO:0036297//interstrand cross-link repair;GO:0048232//male gamete generation;GO:0071897//DNA biosynthetic process	--
ENSG00000125337	0	0	0.021	0	0	0	0	0	1	0	0	0	KIF25	kinesin family member 25 [Source:HGNC Symbol;Acc:HGNC:6390]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity	GO:0000070//mitotic sister chromatid segregation;GO:0006996//organelle organization;GO:0007018//microtubule-based movement;GO:0010507//negative regulation of autophagy;GO:0046603//negative regulation of mitotic centrosome separation;GO:0051289//protein homotetramerization;GO:0051294//establishment of spindle orientation;GO:0051647//nucleus localization	--
ENSG00000125347	3.076	2.91	2.26	2.906	2.336	2.189	111	95	55	53	86	62	IRF1	interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116]	Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Immune system;Infectious disease: bacterial;Endocrine system	ko05165//Human papillomavirus infection;ko04668//TNF signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05133//Pertussis;ko04917//Prolactin signaling pathway	K09444;K09444;K09444;K09444;K09444	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0002376//immune system process;GO:0002819//regulation of adaptive immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0032481//positive regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0035458//cellular response to interferon-beta;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050776//regulation of immune response;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation"	IRF
ENSG00000125351	2.002	1.355	1.258	0.864	1.173	1.56	97	66	45	31	48	55	UPF3B	UPF3B regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:20439]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14328;K14328	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite;GO:0035145//exon-exon junction complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006913//nucleocytoplasmic transport;GO:0045727//positive regulation of translation;GO:0051028//mRNA transport"	--
ENSG00000125352	8.31	8.762	7.622	8.116	8.974	8.421	217	230	147	157	198	160	RNF113A	ring finger protein 113A [Source:HGNC Symbol;Acc:HGNC:12974]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0008380//RNA splicing;GO:0016567//protein ubiquitination;GO:0018276//isopeptide cross-linking via N6-glycyl-L-lysine;GO:0034247//snoRNA splicing;GO:0070100//negative regulation of chemokine-mediated signaling pathway"	--
ENSG00000125354	1.956	1.942	2.299	2.007	1.48	1.926	100	109	83	77	83	85	SEPTIN6	septin 6 [Source:HGNC Symbol;Acc:HGNC:15848]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16939;K16939	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005940//septin ring;GO:0008021//synaptic vesicle;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031105//septin complex;GO:0031514//motile cilium;GO:0032153//cell division site;GO:0032154//cleavage furrow;GO:0032173//septin collar;GO:0042995//cell projection;GO:0043679//axon terminus;GO:0097227//sperm annulus;GO:0098793//presynapse"	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0060090//molecular adaptor activity	GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0060271//cilium assembly;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000125355	12.817	10.212	12.508	18.61	16.46	15.912	770	707	606	918	905	802	TMEM255A	transmembrane protein 255A [Source:HGNC Symbol;Acc:HGNC:26086]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0009617//response to bacterium	--
ENSG00000125356	42.486	37.369	48.687	67.096	36.326	50.364	371	328	314	434	268	320	NDUFA1	NADH:ubiquinone oxidoreductase subunit A1 [Source:HGNC Symbol;Acc:HGNC:7683]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945;K03945	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000125363	0	0	0	0	0	0	0	0	0	0	0	0	AMELX	amelogenin X-linked [Source:HGNC Symbol;Acc:HGNC:461]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030345//structural constituent of tooth enamel;GO:0042802//identical protein binding;GO:0046848//hydroxyapatite binding	GO:0001649//osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0002062//chondrocyte differentiation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0031214//biomineral tissue development;GO:0032967//positive regulation of collagen biosynthetic process;GO:0034505//tooth mineralization;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0051592//response to calcium ion;GO:0070166//enamel mineralization;GO:0070172//positive regulation of tooth mineralization;GO:0097186//amelogenesis	--
ENSG00000125375	3.638	4.975	2.922	2.691	4.465	2.671	146.72	163.46	84.81	84.9	141.39	88.47	DMAC2L	distal membrane arm assembly component 2 like [Source:HGNC Symbol;Acc:HGNC:18799]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0015078//proton transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:1902600//proton transmembrane transport	--
ENSG00000125378	69.987	73.075	103.368	91.733	92.765	110.553	2544	2531	2637	2485	2723	2816	BMP4	bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cellular community - eukaryotes;Cardiovascular disease;Endocrine system;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04919//Thyroid hormone signaling pathway;ko04350//TGF-beta signaling pathway;ko05217//Basal cell carcinoma	K04662;K04662;K04662;K04662;K04662;K04662;K04662;K04662	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0039706//co-receptor binding;GO:0042056//chemoattractant activity;GO:0070700//BMP receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001649//osteoblast differentiation;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001707//mesoderm formation;GO:0001759//organ induction;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0001843//neural tube closure;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001944//vasculature development;GO:0001958//endochondral ossification;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0002062//chondrocyte differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002320//lymphoid progenitor cell differentiation;GO:0003014//renal system process;GO:0003130//BMP signaling pathway involved in heart induction;GO:0003139//secondary heart field specification;GO:0003148//outflow tract septum morphogenesis;GO:0003149//membranous septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003163//sinoatrial node development;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003197//endocardial cushion development;GO:0003279//cardiac septum development;GO:0003323//type B pancreatic cell development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0007165//signal transduction;GO:0007182//common-partner SMAD protein phosphorylation;GO:0007281//germ cell development;GO:0007492//endoderm development;GO:0007500//mesodermal cell fate determination;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009791//post-embryonic development;GO:0009888//tissue development;GO:0009948//anterior/posterior axis specification;GO:0010159//specification of animal organ position;GO:0010453//regulation of cell fate commitment;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010942//positive regulation of cell death;GO:0021537//telencephalon development;GO:0021904//dorsal/ventral neural tube patterning;GO:0021978//telencephalon regionalization;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030224//monocyte differentiation;GO:0030225//macrophage differentiation;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030335//positive regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0032092//positive regulation of protein binding;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0034504//protein localization to nucleus;GO:0035116//embryonic hindlimb morphogenesis;GO:0035990//tendon cell differentiation;GO:0035993//deltoid tuberosity development;GO:0042306//regulation of protein import into nucleus;GO:0042326//negative regulation of phosphorylation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042476//odontogenesis;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045165//cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045786//negative regulation of cell cycle;GO:0045839//negative regulation of mitotic nuclear division;GO:0045843//negative regulation of striated muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048333//mesodermal cell differentiation;GO:0048392//intermediate mesodermal cell differentiation;GO:0048593//camera-type eye morphogenesis;GO:0048598//embryonic morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048660//regulation of smooth muscle cell proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048663//neuron fate commitment;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048745//smooth muscle tissue development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050918//positive chemotaxis;GO:0051145//smooth muscle cell differentiation;GO:0051150//regulation of smooth muscle cell differentiation;GO:0051216//cartilage development;GO:0055007//cardiac muscle cell differentiation;GO:0055020//positive regulation of cardiac muscle fiber development;GO:0060113//inner ear receptor cell differentiation;GO:0060197//cloacal septation;GO:0060235//lens induction in camera-type eye;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060348//bone development;GO:0060363//cranial suture morphogenesis;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060425//lung morphogenesis;GO:0060429//epithelium development;GO:0060433//bronchus development;GO:0060438//trachea development;GO:0060440//trachea formation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060449//bud elongation involved in lung branching;GO:0060502//epithelial cell proliferation involved in lung morphogenesis;GO:0060503//bud dilation involved in lung branching;GO:0060512//prostate gland morphogenesis;GO:0060548//negative regulation of cell death;GO:0060592//mammary gland formation;GO:0060684//epithelial-mesenchymal cell signaling;GO:0060686//negative regulation of prostatic bud formation;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060688//regulation of morphogenesis of a branching structure;GO:0060976//coronary vasculature development;GO:0061035//regulation of cartilage development;GO:0061036//positive regulation of cartilage development;GO:0061047//positive regulation of branching involved in lung morphogenesis;GO:0061149//BMP signaling pathway involved in ureter morphogenesis;GO:0061151//BMP signaling pathway involved in renal system segmentation;GO:0061155//pulmonary artery endothelial tube morphogenesis;GO:0061312//BMP signaling pathway involved in heart development;GO:0061626//pharyngeal arch artery morphogenesis;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071773//cellular response to BMP stimulus;GO:0071893//BMP signaling pathway involved in nephric duct formation;GO:0072015//glomerular visceral epithelial cell development;GO:0072097//negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway;GO:0072101//specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway;GO:0072104//glomerular capillary formation;GO:0072125//negative regulation of glomerular mesangial cell proliferation;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0072192//ureter epithelial cell differentiation;GO:0072193//ureter smooth muscle cell differentiation;GO:0072198//mesenchymal cell proliferation involved in ureter development;GO:0072200//negative regulation of mesenchymal cell proliferation involved in ureter development;GO:0072205//metanephric collecting duct development;GO:0090184//positive regulation of kidney development;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:0090194//negative regulation of glomerulus development;GO:1900745//positive regulation of p38MAPK cascade;GO:1901964//positive regulation of cell proliferation involved in outflow tract morphogenesis;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:1905312//positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:2000005//negative regulation of metanephric S-shaped body morphogenesis;GO:2000007//negative regulation of metanephric comma-shaped body morphogenesis;GO:2000137//negative regulation of cell proliferation involved in heart morphogenesis;GO:2001012//mesenchymal cell differentiation involved in renal system development;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000125384	0.177	0.156	0.133	0.265	0.186	0.081	9	8	5	10	8	3	PTGER2	prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Sensory system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko04924//Renin secretion	K04259;K04259;K04259;K04259;K04259;K04259	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004957//prostaglandin E receptor activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone;GO:0042127//regulation of cell population proliferation;GO:0071380//cellular response to prostaglandin E stimulus	--
ENSG00000125386	8.435	8.359	8.035	7.424	8.224	7.151	865	856	599	566	710	518	FAM193A	family with sequence similarity 193 member A [Source:HGNC Symbol;Acc:HGNC:16822]	-	-	-	-	-	-	-	--
ENSG00000125388	2.08	1.856	1.826	1.787	1.461	2.183	94	82	61	58	55	70	GRK4	G protein-coupled receptor kinase 4 [Source:HGNC Symbol;Acc:HGNC:4543]	Cellular Processes;Organismal Systems;Human Diseases	Transport and catabolism;Immune system;Substance dependence	ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko05032//Morphine addiction	K08291;K08291;K08291	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0097381//photoreceptor disc membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0050254//rhodopsin kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0031623//receptor internalization	--
ENSG00000125398	57.177	57.397	55.48	56.692	58.749	59.99	4662	4704	3341	3424	4047	3559	SOX9	SRY-box transcription factor 9 [Source:HGNC Symbol;Acc:HGNC:11204]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K18435	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0097157//pre-mRNA intronic binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001708//cell fate specification;GO:0001837//epithelial to mesenchymal transition;GO:0001894//tissue homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0001942//hair follicle development;GO:0002009//morphogenesis of an epithelium;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002062//chondrocyte differentiation;GO:0002063//chondrocyte development;GO:0002683//negative regulation of immune system process;GO:0003170//heart valve development;GO:0003179//heart valve morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003188//heart valve formation;GO:0003203//endocardial cushion morphogenesis;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0003415//chondrocyte hypertrophy;GO:0003430//growth plate cartilage chondrocyte growth;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0007283//spermatogenesis;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0010468//regulation of gene expression;GO:0010564//regulation of cell cycle process;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0014032//neural crest cell development;GO:0014036//neural crest cell fate specification;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019100//male germ-line sex determination;GO:0019933//cAMP-mediated signaling;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030198//extracellular matrix organization;GO:0030238//male sex determination;GO:0030279//negative regulation of ossification;GO:0030502//negative regulation of bone mineralization;GO:0030850//prostate gland development;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0030879//mammary gland development;GO:0030903//notochord development;GO:0030916//otic vesicle formation;GO:0031018//endocrine pancreas development;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032808//lacrimal gland development;GO:0034504//protein localization to nucleus;GO:0035019//somatic stem cell population maintenance;GO:0035622//intrahepatic bile duct development;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0045165//cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046322//negative regulation of fatty acid oxidation;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0048709//oligodendrocyte differentiation;GO:0048873//homeostasis of number of cells within a tissue;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0060008//Sertoli cell differentiation;GO:0060009//Sertoli cell development;GO:0060018//astrocyte fate commitment;GO:0060041//retina development in camera-type eye;GO:0060174//limb bud formation;GO:0060221//retinal rod cell differentiation;GO:0060350//endochondral bone morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060487//lung epithelial cell differentiation;GO:0060512//prostate gland morphogenesis;GO:0060517//epithelial cell proliferation involved in prostatic bud elongation;GO:0060532//bronchus cartilage development;GO:0060534//trachea cartilage development;GO:0060729//intestinal epithelial structure maintenance;GO:0060784//regulation of cell proliferation involved in tissue homeostasis;GO:0061036//positive regulation of cartilage development;GO:0061046//regulation of branching involved in lung morphogenesis;GO:0061138//morphogenesis of a branching epithelium;GO:0061145//lung smooth muscle development;GO:0065003//protein-containing complex assembly;GO:0070168//negative regulation of biomineral tissue development;GO:0070371//ERK1 and ERK2 cascade;GO:0070384//Harderian gland development;GO:0070542//response to fatty acid;GO:0071260//cellular response to mechanical stimulus;GO:0071300//cellular response to retinoic acid;GO:0071347//cellular response to interleukin-1;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071504//cellular response to heparin;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071599//otic vesicle development;GO:0071773//cellular response to BMP stimulus;GO:0072034//renal vesicle induction;GO:0072170//metanephric tubule development;GO:0072189//ureter development;GO:0072190//ureter urothelium development;GO:0072193//ureter smooth muscle cell differentiation;GO:0072197//ureter morphogenesis;GO:0072289//metanephric nephron tubule formation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090103//cochlea morphogenesis;GO:0090184//positive regulation of kidney development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0097065//anterior head development;GO:0098609//cell-cell adhesion;GO:1901203//positive regulation of extracellular matrix assembly;GO:1902732//positive regulation of chondrocyte proliferation;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1904864//negative regulation of beta-catenin-TCF complex assembly;GO:2000020//positive regulation of male gonad development;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:2000794//regulation of epithelial cell proliferation involved in lung morphogenesis;GO:2001054//negative regulation of mesenchymal cell apoptotic process"	HMG
ENSG00000125409	0.085	0.147	0.12	0	0.105	0.081	1	5	3	0	3	2	TEKT3	tektin 3 [Source:HGNC Symbol;Acc:HGNC:14293]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0002081//outer acrosomal membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility;GO:0060378//regulation of brood size	--
ENSG00000125414	0	0.02	0	0.027	0	0	0	1	0	1	0	0	MYH2	myosin heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:7572]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0005911//cell-cell junction;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0032982//myosin filament;GO:0032991//protein-containing complex	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0030049//muscle filament sliding	--
ENSG00000125430	1.694	1.317	1.256	1.303	2.553	2.137	172.9	126.08	88.8	101.54	200.47	145.51	HS3ST3B1	heparan sulfate-glucosamine 3-sulfotransferase 3B1 [Source:HGNC Symbol;Acc:HGNC:5198]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K07809	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity;GO:0033872//[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0006477//protein sulfation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification"	--
ENSG00000125434	2.815	2.332	3.027	2.734	2.913	3.066	118.22	99.47	93.51	84.05	104.28	96.03	SLC25A35	solute carrier family 25 member 35 [Source:HGNC Symbol;Acc:HGNC:31921]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000125445	24.007	22.359	28.387	31.338	21.982	21.008	594	562	535	552	476	392	MRPS7	mitochondrial ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:14499]	Genetic Information Processing	Translation	ko03010//Ribosome	K02992	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding	GO:0000028//ribosomal small subunit assembly;GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000125447	8.929	10.296	10.997	9.454	11.837	12.148	719	778	634	514	678	617	GGA3	"golgi associated, gamma adaptin ear containing, ARF binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17079]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12404	GO:0005764//lysosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0055038//recycling endosome membrane;GO:0098588//bounding membrane of organelle	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding	GO:0006622//protein targeting to lysosome;GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0034394//protein localization to cell surface;GO:0043001//Golgi to plasma membrane protein transport;GO:0045732//positive regulation of protein catabolic process;GO:0051641//cellular localization;GO:0061462//protein localization to lysosome;GO:1902430//negative regulation of amyloid-beta formation	--
ENSG00000125449	3.335	4.606	4.124	4.675	3.774	4.683	136	194	119	136	130	129	ARMC7	armadillo repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:26168]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000125450	10.266	10.892	13.301	9.449	9.376	11.684	440	479	357	304	344	359	NUP85	nucleoporin 85 [Source:HGNC Symbol;Acc:HGNC:8734]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14304;K14304	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane"	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	"GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006935//chemotaxis;GO:0015031//protein transport;GO:0030032//lamellipodium assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048246//macrophage chemotaxis;GO:0051028//mRNA transport;GO:0072006//nephron development"	--
ENSG00000125454	3.796	3.591	4.073	4.243	4.071	5.371	107	101	90	97	110	118	SLC25A19	solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0015234//thiamine transmembrane transporter activity;GO:0030233//deoxynucleotide transmembrane transporter activity;GO:0090422//thiamine pyrophosphate transmembrane transporter activity	GO:0030302//deoxynucleotide transport;GO:0030974//thiamine pyrophosphate transmembrane transport;GO:0042723//thiamine-containing compound metabolic process;GO:0055085//transmembrane transport	--
ENSG00000125457	9.994	9.558	12.09	11.471	10.169	9.843	286	278	247	242	243	208	MIF4GD	MIF4G domain containing [Source:HGNC Symbol;Acc:HGNC:24030]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0062073//histone mRNA stem-loop binding complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008494//translation activator activity;GO:0042802//identical protein binding	GO:0002191//cap-dependent translational initiation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation	--
ENSG00000125458	12.493	13.973	12.887	16.472	14.534	12.144	233	261	175	225	226	164	NT5C	"5', 3'-nucleotidase, cytosolic [Source:HGNC Symbol;Acc:HGNC:17144]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0008252//nucleotidase activity;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019103//pyrimidine nucleotide binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050483//IMP 5'-nucleotidase activity	GO:0000255//allantoin metabolic process;GO:0006204//IMP catabolic process;GO:0006249//dCMP catabolic process;GO:0009117//nucleotide metabolic process;GO:0009223//pyrimidine deoxyribonucleotide catabolic process;GO:0009264//deoxyribonucleotide catabolic process;GO:0016311//dephosphorylation;GO:0046050//UMP catabolic process;GO:0046055//dGMP catabolic process;GO:0046074//dTMP catabolic process;GO:0046079//dUMP catabolic process	--
ENSG00000125459	8.5	8.911	10.522	8.191	8.082	7.717	425	428.77	362.93	303.93	331.05	271.32	MSTO1	misato mitochondrial distribution and morphology regulator 1 [Source:HGNC Symbol;Acc:HGNC:29678]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0048311//mitochondrion distribution	--
ENSG00000125482	2.878	2.583	2.804	1.678	2.045	1.476	160	138	135	67	92	70	TTF1	transcription termination factor 1 [Source:HGNC Symbol;Acc:HGNC:12397]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K15225	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	"GO:0006353//DNA-templated transcription, termination;GO:0006363//termination of RNA polymerase I transcription;GO:0008156//negative regulation of DNA replication"	MYB
ENSG00000125484	7.4	7.385	6.991	7.658	7.668	7.093	1264.51	1277.97	878.31	888.95	1084.23	902.42	GTF3C4	general transcription factor IIIC subunit 4 [Source:HGNC Symbol;Acc:HGNC:4667]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0016573//histone acetylation;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III;GO:0050790//regulation of catalytic activity	--
ENSG00000125485	3.264	3.809	4.399	3.059	4.079	3.637	244.49	285.03	243.69	188.05	246.77	211.58	DDX31	DEAD-box helicase 31 [Source:HGNC Symbol;Acc:HGNC:16715]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0042254//ribosome biogenesis	--
ENSG00000125492	0	0	0	0	0	0	0	0	0	0	0	0	BARHL1	BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007605//sensory perception of sound;GO:0030901//midbrain development;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000125498	0	0	0	0	0	0	0	0	0	0	0	0	KIR2DL1	"killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 [Source:HGNC Symbol;Acc:HGNC:6329]"	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K07981;K07981;K07981	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002769//natural killer cell inhibitory signaling pathway;GO:0006955//immune response	--
ENSG00000125503	16.485	15.995	17.148	18.728	18.791	19.985	793	840	678	732	827	735	PPP1R12C	protein phosphatase 1 regulatory subunit 12C [Source:HGNC Symbol;Acc:HGNC:14947]	Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Cell motility;Cancer: overview;Cellular community - eukaryotes;Endocrine system;Circulatory system	ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction	K17457;K17457;K17457;K17457;K17457	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity;GO:0019901//protein kinase binding	GO:0007165//signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity	--
ENSG00000125505	41.335	42.759	41.83	42.629	46.035	40.596	1718	1748	1267	1363	1639	1259	MBOAT7	membrane bound O-acyltransferase domain containing 7 [Source:HGNC Symbol;Acc:HGNC:15505]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K13516	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0071617//lysophospholipid acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0021591//ventricular system development;GO:0021819//layer formation in cerebral cortex;GO:0030258//lipid modification;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0046488//phosphatidylinositol metabolic process;GO:0090207//regulation of triglyceride metabolic process	--
ENSG00000125508	0.012	0.059	0.048	0.064	0.168	0.016	1	5	3	4	12	1	SRMS	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [Source:HGNC Symbol;Acc:HGNC:11298]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0045087//innate immune response	--
ENSG00000125510	0.169	0.26	0.25	0.178	0.151	0.317	11	17	12	9	9	15	OPRL1	opioid related nociceptin receptor 1 [Source:HGNC Symbol;Acc:HGNC:8155]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04216	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection	GO:0001626//nociceptin receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007600//sensory perception;GO:0007610//behavior;GO:0019233//sensory perception of pain;GO:0032355//response to estradiol;GO:0035810//positive regulation of urine volume;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0042755//eating behavior;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0044849//estrous cycle;GO:0045776//negative regulation of blood pressure;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051930//regulation of sensory perception of pain;GO:0060454//positive regulation of gastric acid secretion;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1904058//positive regulation of sensory perception of pain;GO:1904059//regulation of locomotor rhythm;GO:1990708//conditioned place preference	--
ENSG00000125520	7.237	8.311	8.416	9.183	8.986	7.701	354.4	409.11	304.41	333.1	371.8	274.39	SLC2A4RG	SLC2A4 regulator [Source:HGNC Symbol;Acc:HGNC:15930]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Others
ENSG00000125522	0	0	0	0	0	0	0	0	0	0	0	0	NPBWR2	neuropeptides B and W receptor 2 [Source:HGNC Symbol;Acc:HGNC:4530]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K08377	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0038003//G protein-coupled opioid receptor signaling pathway	--
ENSG00000125531	0.354	0.43	0.12	0.022	0.097	0.09	12	12	2	1	5	4	FNDC11	fibronectin type III domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28764]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000125533	0	0	0	0	0	0	0	0	0	0	0	0	BHLHE23	basic helix-loop-helix family member e23 [Source:HGNC Symbol;Acc:HGNC:16093]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046548//retinal rod cell development;GO:0046671//negative regulation of retinal cell programmed cell death;GO:0048050//post-embryonic eye morphogenesis;GO:0048468//cell development"	bHLH
ENSG00000125534	71.299	81.233	74.857	95.718	83.868	70.054	1221	1393	942	1215	1213	873	PPDPF	pancreatic progenitor cell differentiation and proliferation factor [Source:HGNC Symbol;Acc:HGNC:16142]	-	-	-	-	-	-	GO:0007275//multicellular organism development;GO:0030154//cell differentiation	--
ENSG00000125538	0.064	0	0	0.112	0	0	2	0	0	1	0	0	IL1B	interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Immune system;Endocrine and metabolic disease;Cell growth and death;Immune disease;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cardiovascular disease;Development and regeneration;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Sensory system;Immune system;Infectious disease: bacterial;Immune disease;Immune system;Infectious disease: bacterial;Infectious disease: parasitic;Endocrine and metabolic disease;Immune disease;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05020//Prion disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05323//Rheumatoid arthritis;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04750//Inflammatory mediator regulation of TRP channels;ko04657//IL-17 signaling pathway;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis;ko05144//Malaria;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease;ko01523//Antifolate resistance	K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519;K04519	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0031982//vesicle	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0000165//MAPK cascade;GO:0001660//fever generation;GO:0001819//positive regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0002711//positive regulation of T cell mediated immunity;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007566//embryo implantation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009743//response to carbohydrate;GO:0010573//vascular endothelial growth factor production;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010829//negative regulation of glucose transmembrane transport;GO:0014805//smooth muscle adaptation;GO:0019221//cytokine-mediated signaling pathway;GO:0030213//hyaluronan biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0030730//sequestering of triglyceride;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0031622//positive regulation of fever generation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032308//positive regulation of prostaglandin secretion;GO:0032496//response to lipopolysaccharide;GO:0032722//positive regulation of chemokine production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0033129//positive regulation of histone phosphorylation;GO:0033198//response to ATP;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0035066//positive regulation of histone acetylation;GO:0035234//ectopic germ cell programmed cell death;GO:0035505//positive regulation of myosin light chain kinase activity;GO:0042102//positive regulation of T cell proliferation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0043491//protein kinase B signaling;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0045833//negative regulation of lipid metabolic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045917//positive regulation of complement activation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046827//positive regulation of protein export from nucleus;GO:0048143//astrocyte activation;GO:0050691//regulation of defense response to virus by host;GO:0050729//positive regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050767//regulation of neurogenesis;GO:0050768//negative regulation of neurogenesis;GO:0050796//regulation of insulin secretion;GO:0050805//negative regulation of synaptic transmission;GO:0050830//defense response to Gram-positive bacterium;GO:0050900//leukocyte migration;GO:0050995//negative regulation of lipid catabolic process;GO:0050996//positive regulation of lipid catabolic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051781//positive regulation of cell division;GO:0060252//positive regulation of glial cell proliferation;GO:0060355//positive regulation of cell adhesion molecule production;GO:0060559//positive regulation of calcidiol 1-monooxygenase activity;GO:0070164//negative regulation of adiponectin secretion;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070487//monocyte aggregation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0071310//cellular response to organic substance;GO:0071407//cellular response to organic cyclic compound;GO:0071466//cellular response to xenobiotic stimulus;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0150078//positive regulation of neuroinflammatory response;GO:1900745//positive regulation of p38MAPK cascade;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902680//positive regulation of RNA biosynthetic process;GO:1903140//regulation of establishment of endothelial barrier;GO:1903597//negative regulation of gap junction assembly;GO:2000556//positive regulation of T-helper 1 cell cytokine production;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000125551	0.402	0.257	0.104	0.451	0.392	0.524	25.17	16.16	4.82	20.9	20.73	23.87	PLGLB2	plasminogen like B2 [Source:HGNC Symbol;Acc:HGNC:9073]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01315;K01315;K01315;K01315	GO:0005576//extracellular region	GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding	GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity	--
ENSG00000125571	0	0	0	0	0	0	0	0	0	0	0	0	IL37	interleukin 37 [Source:HGNC Symbol;Acc:HGNC:15563]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05485;K05485	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0050727//regulation of inflammatory response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000125611	10.435	10.85	11.77	15.754	14.471	12.545	119	123	97	137	143	108	CHCHD5	coiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17840]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000125618	0.169	0.094	0.072	0.409	0.063	0.101	14	4	4	5	4	5	PAX8	paired box 8 [Source:HGNC Symbol;Acc:HGNC:8622]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04918//Thyroid hormone synthesis;ko05216//Thyroid cancer	K09293;K09293;K09293;K09293	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004996//thyroid-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001655//urogenital system development;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0003281//ventricular septum development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006790//sulfur compound metabolic process;GO:0007417//central nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0030154//cell differentiation;GO:0030878//thyroid gland development;GO:0038194//thyroid-stimulating hormone signaling pathway;GO:0039003//pronephric field specification;GO:0042472//inner ear morphogenesis;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048793//pronephros development;GO:0048856//anatomical structure development;GO:0071371//cellular response to gonadotropin stimulus;GO:0071599//otic vesicle development;GO:0072050//S-shaped body morphogenesis;GO:0072073//kidney epithelium development;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0072164//mesonephric tubule development;GO:0072207//metanephric epithelium development;GO:0072221//metanephric distal convoluted tubule development;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0072284//metanephric S-shaped body morphogenesis;GO:0072289//metanephric nephron tubule formation;GO:0072305//negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development;GO:1900215//negative regulation of apoptotic process involved in metanephric collecting duct development;GO:1900218//negative regulation of apoptotic process involved in metanephric nephron tubule development;GO:2000594//positive regulation of metanephric DCT cell differentiation;GO:2000611//positive regulation of thyroid hormone generation;GO:2000612//regulation of thyroid-stimulating hormone secretion"	PAX
ENSG00000125629	8.419	5.844	6.359	6.261	6.792	8.06	573	434	347	309	326	327	INSIG2	insulin induced gene 2 [Source:HGNC Symbol;Acc:HGNC:20452]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032937//SREBP-SCAP-Insig complex	GO:0005515//protein binding;GO:0008142//oxysterol binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006991//response to sterol depletion;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010894//negative regulation of steroid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0032933//SREBP signaling pathway;GO:0033993//response to lipid;GO:0036316//SREBP-SCAP complex retention in endoplasmic reticulum;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0060021//roof of mouth development;GO:0060363//cranial suture morphogenesis;GO:0070542//response to fatty acid	--
ENSG00000125630	9.182	9.17	11.365	11.354	9.526	10.769	775	809	611	615	711	663	POLR1B	RNA polymerase I subunit B [Source:HGNC Symbol;Acc:HGNC:20454]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K03002	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0032549//ribonucleoside binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0007566//embryo implantation;GO:0009303//rRNA transcription;GO:0014029//neural crest formation;GO:0017126//nucleologenesis"	--
ENSG00000125633	7.516	6.395	6.468	4.848	5.99	6.429	1066	912	678	510	718	664	CCDC93	coiled-coil domain containing 93 [Source:HGNC Symbol;Acc:HGNC:25611]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0032456//endocytic recycling	--
ENSG00000125637	2.058	1.531	1.564	1.413	1.713	1.139	210	217	187	149	194	158	PSD4	pleckstrin and Sec7 domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19096]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12494	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding	GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000125648	52.955	58.511	56.725	69.697	66.316	59.844	3279	3606	2539	3139	3440	2611	SLC25A23	solute carrier family 25 member 23 [Source:HGNC Symbol;Acc:HGNC:19375]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005347//ATP transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002082//regulation of oxidative phosphorylation;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0015867//ATP transport;GO:0036444//calcium import into the mitochondrion;GO:0043457//regulation of cellular respiration;GO:0051282//regulation of sequestering of calcium ion;GO:0051503//adenine nucleotide transport;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0055085//transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0097274//urea homeostasis;GO:1900069//regulation of cellular hyperosmotic salinity response	--
ENSG00000125650	1.63	1.521	1.886	2.03	1.474	1.728	130.06	124	113	122	101	102	PSPN	persephin [Source:HGNC Symbol;Acc:HGNC:9579]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0008083//growth factor activity;GO:0030116//glial cell-derived neurotrophic factor receptor binding;GO:0030971//receptor tyrosine kinase binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007417//central nervous system development	--
ENSG00000125651	66.319	62.242	67.677	68.178	61.609	61.485	2301	2418	1807	1980	2113	1565	GTF2F1	general transcription factor IIF subunit 1 [Source:HGNC Symbol;Acc:HGNC:4652]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03138	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005674//transcription factor TFIIF complex;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0001096//TFIIF-class transcription factor complex binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0019211//phosphatase activator activity;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:1990841//promoter-specific chromatin binding	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0009615//response to virus;GO:0032091//negative regulation of protein binding;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity	--
ENSG00000125652	24.363	27.563	28.047	45.518	31.964	29.801	471.94	534	393	652	541	432	ALKBH7	alkB homolog 7 [Source:HGNC Symbol;Acc:HGNC:21306]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0006631//fatty acid metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010883//regulation of lipid storage;GO:0012501//programmed cell death;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	--
ENSG00000125656	35.146	39.515	44.894	49.807	44.339	47.587	733	774	642	700	754.5	715	CLPP	caseinolytic mitochondrial matrix peptidase proteolytic subunit [Source:HGNC Symbol;Acc:HGNC:2084]	Organismal Systems	Aging	ko04212//Longevity regulating pathway - worm	K01358	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0009368//endopeptidase Clp complex	GO:0004175//endopeptidase activity;GO:0004176//ATP-dependent peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0051117//ATPase binding	GO:0006508//proteolysis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0033619//membrane protein proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000125657	0.561	0.881	0.839	0.916	1.152	1.419	19	30	21	23	33	35	TNFSF9	TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05472	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0042104//positive regulation of activated T cell proliferation;GO:0042129//regulation of T cell proliferation;GO:0042981//regulation of apoptotic process;GO:0045585//positive regulation of cytotoxic T cell differentiation	--
ENSG00000125675	0.29	0.096	0.07	0.131	0.095	0.071	14	6	1	6	5	1	GRIA3	glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Cancer: overview;Signal transduction;Nervous system;Neurodegenerative disease;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko05202//Transcriptional misregulation in cancer;ko04024//cAMP signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04730//Long-term depression;ko05033//Nicotine addiction	K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199;K05199	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004971//AMPA glutamate receptor activity;GO:0005216//ion channel activity;GO:0015276//ligand-gated ion channel activity;GO:0038023//signaling receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0060078//regulation of postsynaptic membrane potential	--
ENSG00000125676	6.743	5.322	4.82	3.341	4.851	5.778	522	380	268	151	272	269	THOC2	THO complex 2 [Source:HGNC Symbol;Acc:HGNC:19073]	Genetic Information Processing;Genetic Information Processing	Transcription;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport	K12879;K12879	"GO:0000346//transcription export complex;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck"	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0048666//neuron development;GO:0048699//generation of neurons;GO:0051028//mRNA transport	--
ENSG00000125686	10.121	8.748	10.039	7.421	9.005	8.777	1533	1376	1152	838	1154	995	MED1	mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234]	Organismal Systems;Human Diseases	Endocrine system;Drug resistance: antineoplastic	ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance	K15144;K15144	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0044877//protein-containing complex binding;GO:0046966//thyroid hormone receptor binding;GO:0050693//LBD domain binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0002088//lens development in camera-type eye;GO:0002154//thyroid hormone mediated signaling pathway;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003406//retinal pigment epithelium development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006590//thyroid hormone generation;GO:0006606//protein import into nucleus;GO:0006702//androgen biosynthetic process;GO:0007420//brain development;GO:0007507//heart development;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010839//negative regulation of keratinocyte proliferation;GO:0030216//keratinocyte differentiation;GO:0030224//monocyte differentiation;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0031100//animal organ regeneration;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:0035050//embryonic heart tube development;GO:0035116//embryonic hindlimb morphogenesis;GO:0035162//embryonic hemopoiesis;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0035855//megakaryocyte development;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0045444//fat cell differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048821//erythrocyte development;GO:0048822//enucleate erythrocyte development;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0060744//mammary gland branching involved in thelarche;GO:0060745//mammary gland branching involved in pregnancy;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0070318//positive regulation of G0 to G1 transition;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071383//cellular response to steroid hormone stimulus;GO:0097067//cellular response to thyroid hormone stimulus;GO:2000347//positive regulation of hepatocyte proliferation;GO:2001141//regulation of RNA biosynthetic process"	--
ENSG00000125691	632.776	644.714	653.837	652.442	524.998	565.387	8355	8558	6386	6359	5863	5426	RPL23	ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02894;K02894	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0032991//protein-containing complex;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0001223//transcription coactivator binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0070180//large ribosomal subunit rRNA binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006610//ribosomal protein import into nucleus;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0032986//protein-DNA complex disassembly;GO:0050821//protein stabilization;GO:0070314//G1 to G0 transition;GO:0072717//cellular response to actinomycin D;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1903450//regulation of G1 to G0 transition;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000125695	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030867//rough endoplasmic reticulum membrane	GO:0005509//calcium ion binding	GO:0032469//endoplasmic reticulum calcium ion homeostasis	--
ENSG00000125703	9.585	9.015	8.996	7.207	8.985	10.366	413	374	259	231	293	255	ATG4C	autophagy related 4C cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:16040]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K08342;K08342	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006914//autophagy;GO:0015031//protein transport;GO:0051697//protein delipidation	--
ENSG00000125726	0	0	0	0	0	0	0	0	0	0	0	0	CD70	CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05470	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0002456//T cell mediated immunity;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0019724//B cell mediated immunity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042100//B cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0097191//extrinsic apoptotic signaling pathway	--
ENSG00000125730	176.069	178.936	205.124	134.164	163.941	174.883	17910	18365	15408	10127	14120	13109	C3	complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Immune disease;Cancer: overview;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05150//Staphylococcus aureus infection;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis;ko05134//Legionellosis	K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990;K03990	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031715//C5L2 anaphylatoxin chemotactic receptor binding	"GO:0001798//positive regulation of type IIa hypersensitivity;GO:0001934//positive regulation of protein phosphorylation;GO:0001970//positive regulation of activation of membrane attack complex;GO:0002376//immune system process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009617//response to bacterium;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010828//positive regulation of glucose transmembrane transport;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010884//positive regulation of lipid storage;GO:0010951//negative regulation of endopeptidase activity;GO:0016322//neuron remodeling;GO:0035846//oviduct epithelium development;GO:0045087//innate immune response;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050766//positive regulation of phagocytosis;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0097242//amyloid-beta clearance;GO:0097278//complement-dependent cytotoxicity;GO:0150062//complement-mediated synapse pruning;GO:0150064//vertebrate eye-specific patterning;GO:1905114//cell surface receptor signaling pathway involved in cell-cell signaling;GO:2000427//positive regulation of apoptotic cell clearance"	--
ENSG00000125731	1.155	1.468	1.056	0.969	1.004	0.823	33	50	27	26	28	28	SH2D3A	SH2 domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16885]	-	-	-	-	-	GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007254//JNK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0050790//regulation of catalytic activity	--
ENSG00000125733	27.844	27.1	29.417	27.982	25.187	26.97	1170	1146	905	858	873	826	TRIP10	thyroid hormone receptor interactor 10 [Source:HGNC Symbol;Acc:HGNC:12304]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K07196	GO:0001891//phagocytic cup;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization	--
ENSG00000125734	28.192	31.359	36.493	39.393	37.868	38.55	1137	1321	1101	1226	1333	1171	GPR108	G protein-coupled receptor 108 [Source:HGNC Symbol;Acc:HGNC:17829]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033106//cis-Golgi network membrane	GO:0005515//protein binding	GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0050776//regulation of immune response	--
ENSG00000125735	0.011	0	0	0	0.013	0	1	0	0	0	1	0	TNFSF14	TNF superfamily member 14 [Source:HGNC Symbol;Acc:HGNC:11930]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Infectious disease: viral;Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko05168//Herpes simplex virus 1 infection;ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05477;K05477;K05477;K05477	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0010820//positive regulation of T cell chemotaxis;GO:0031295//T cell costimulation;GO:0042098//T cell proliferation;GO:0042110//T cell activation;GO:0043029//T cell homeostasis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045663//positive regulation of myoblast differentiation;GO:0071260//cellular response to mechanical stimulus;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901741//positive regulation of myoblast fusion	--
ENSG00000125740	0.362	0.351	0.169	0.136	0.245	0.119	17	19	8	7	16	6	FOSB	"FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797]"	Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Substance dependence;Development and regeneration;Immune system;Substance dependence;Substance dependence	ko05034//Alcoholism;ko04380//Osteoclast differentiation;ko04657//IL-17 signaling pathway;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K09029;K09029;K09029;K09029;K09029	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007565//female pregnancy;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0032570//response to progesterone;GO:0032870//cellular response to hormone stimulus;GO:0043278//response to morphine;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051412//response to corticosterone;GO:0051591//response to cAMP;GO:0071277//cellular response to calcium ion"	TF_bZIP
ENSG00000125741	5.243	6.048	5.807	8.557	6.441	8.444	678	786	532	690	749	641	OPA3	outer mitochondrial membrane lipid metabolism regulator OPA3 [Source:HGNC Symbol;Acc:HGNC:8142]	-	-	-	-	GO:0005739//mitochondrion	-	GO:0007601//visual perception;GO:0019216//regulation of lipid metabolic process;GO:0050896//response to stimulus	--
ENSG00000125743	45.033	48.419	45.404	40.058	33.354	39.659	481	523	359	320	303	309	SNRPD2	small nuclear ribonucleoprotein D2 polypeptide [Source:HGNC Symbol;Acc:HGNC:11159]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11096	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0070062//extracellular exosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000125744	2.941	3.395	3.099	2.465	2.271	2.116	97	147	79	72	84	68	RTN2	reticulon 2 [Source:HGNC Symbol;Acc:HGNC:10468]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014802//terminal cisterna;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030315//T-tubule;GO:0033017//sarcoplasmic reticulum membrane;GO:0042383//sarcolemma;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0010467//gene expression;GO:0015031//protein transport;GO:0046324//regulation of glucose import;GO:0065002//intracellular protein transmembrane transport;GO:1902430//negative regulation of amyloid-beta formation	--
ENSG00000125746	10.444	11.915	11.261	11.577	11.456	13.872	327	404	341	337	388	391	EML2	EMAP like 2 [Source:HGNC Symbol;Acc:HGNC:18035]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072686//mitotic spindle	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0015631//tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0010968//regulation of microtubule nucleation;GO:0031115//negative regulation of microtubule polymerization	--
ENSG00000125753	11.319	11.044	13.934	13.294	13.772	13.304	522	485	341	410	466	309	VASP	vasodilator stimulated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:12652]	Environmental Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cellular community - eukaryotes;Cellular community - eukaryotes;Signal transduction;Immune system;Immune system;Immune system	ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04611//Platelet activation;ko04670//Leukocyte transendothelial migration	K06274;K06274;K06274;K06274;K06274;K06274;K06274	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0031258//lamellipodium membrane;GO:0031527//filopodium membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0017124//SH3 domain binding;GO:0045296//cadherin binding	GO:0001843//neural tube closure;GO:0007411//axon guidance;GO:0008154//actin polymerization or depolymerization;GO:0030036//actin cytoskeleton organization;GO:0030838//positive regulation of actin filament polymerization;GO:0051289//protein homotetramerization	--
ENSG00000125755	24.208	26.515	25.26	24.016	24.752	22.615	1999	2116	1483	1429	1698	1298	SYMPK	symplekin scaffold protein [Source:HGNC Symbol;Acc:HGNC:22935]	Cellular Processes;Genetic Information Processing	Cellular community - eukaryotes;Translation	ko04530//Tight junction;ko03015//mRNA surveillance pathway	K06100;K06100	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0097165//nuclear stress granule	GO:0005515//protein binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0007155//cell adhesion;GO:0032091//negative regulation of protein binding;GO:0035307//positive regulation of protein dephosphorylation	--
ENSG00000125772	7.676	6.275	6.562	5.883	5.775	8.784	739	589	461	402	512	495	GPCPD1	glycerophosphocholine phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:26957]	Human Diseases;Metabolism	Cancer: overview;Lipid metabolism	ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism	K18695;K18695	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030246//carbohydrate binding;GO:0047389//glycerophosphocholine phosphodiesterase activity;GO:2001070//starch binding	GO:0006629//lipid metabolic process;GO:0007519//skeletal muscle tissue development;GO:0046475//glycerophospholipid catabolic process	--
ENSG00000125775	0.24	0.376	0.288	0.052	0.732	0.425	7	11	6	1	18	9	SDCBP2	syndecan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15756]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008022//protein C-terminus binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity"	GO:0007399//nervous system development;GO:0008283//cell population proliferation;GO:0035556//intracellular signal transduction;GO:0046907//intracellular transport	--
ENSG00000125779	11.269	9.384	10.21	9.897	9.517	12.022	543.98	497.79	434.51	447.22	443.96	482.25	PANK2	pantothenate kinase 2 [Source:HGNC Symbol;Acc:HGNC:15894]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K09680;K09680	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004594//pantothenate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001525//angiogenesis;GO:0007286//spermatid development;GO:0009060//aerobic respiration;GO:0015937//coenzyme A biosynthetic process;GO:0015939//pantothenate metabolic process;GO:0016310//phosphorylation;GO:0019217//regulation of fatty acid metabolic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0070584//mitochondrion morphogenesis;GO:0090207//regulation of triglyceride metabolic process;GO:1904251//regulation of bile acid metabolic process	--
ENSG00000125780	0.018	0	0.123	0.025	0	0	1	0	5	1	0	0	TGM3	transglutaminase 3 [Source:HGNC Symbol;Acc:HGNC:11779]	-	-	-	-	GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0003824//catalytic activity;GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	GO:0006464//cellular protein modification process;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031069//hair follicle morphogenesis;GO:0031424//keratinization;GO:0043163//cell envelope organization	--
ENSG00000125787	0.064	0	0	0	0	0	1	0	0	0	0	0	GNRH2	gonadotropin releasing hormone 2 [Source:HGNC Symbol;Acc:HGNC:4420]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04912//GnRH signaling pathway;ko04929//GnRH secretion	K05252;K05252;K05252	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005183//gonadotropin hormone-releasing hormone activity;GO:0031530//gonadotropin-releasing hormone receptor binding	GO:0000003//reproduction;GO:0007165//signal transduction;GO:0007275//multicellular organism development	--
ENSG00000125788	0	0	0	0	0	0	0	0	0	0	0	0	DEFB126	defensin beta 126 [Source:HGNC Symbol;Acc:HGNC:15900]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0007338//single fertilization;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000125798	0.02	0	0	0	0	0	1	0	0	0	0	0	FOXA2	forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022]	Organismal Systems;Human Diseases	Aging;Endocrine and metabolic disease	ko04213//Longevity regulating pathway - multiple species;ko04950//Maturity onset diabetes of the young	K08035;K08035	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030054//cell junction	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0001708//cell fate specification;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008344//adult locomotory behavior;GO:0009653//anatomical structure morphogenesis;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030154//cell differentiation;GO:0030193//regulation of blood coagulation;GO:0031018//endocrine pancreas development;GO:0033132//negative regulation of glucokinase activity;GO:0040019//positive regulation of embryonic development;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061987//negative regulation of transcription from RNA polymerase II promoter by glucose;GO:0070741//response to interleukin-6;GO:0071542//dopaminergic neuron differentiation;GO:0090009//primitive streak formation;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:2000543//positive regulation of gastrulation;GO:2000971//negative regulation of detection of glucose"	Fork_head
ENSG00000125810	0	0	0	0	0.06	0	0	0	0	0	7	0	CD93	CD93 molecule [Source:HGNC Symbol;Acc:HGNC:15855]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0001849//complement component C1q complex binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0042116//macrophage activation;GO:0098609//cell-cell adhesion	--
ENSG00000125812	7.031	5.834	6.477	5.441	5.46	5.634	681	588	469	400	460	411	GZF1	GDNF inducible zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:15808]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated"	ZBTB
ENSG00000125813	0	0	0	0	0	0	0	0	0	0	0	0	PAX1	paired box 1 [Source:HGNC Symbol;Acc:HGNC:8615]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0008283//cell population proliferation;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048538//thymus development;GO:0048856//anatomical structure development;GO:0060017//parathyroid gland development;GO:0060349//bone morphogenesis;GO:0061056//sclerotome development"	PAX
ENSG00000125814	2.784	2.389	2.844	2.392	2.537	2.889	221	191	167	141	170	167	NAPB	NSF attachment protein beta [Source:HGNC Symbol;Acc:HGNC:15751]	-	-	-	-	GO:0016020//membrane;GO:0031201//SNARE complex;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0005483//soluble NSF attachment protein activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006886//intracellular protein transport;GO:0010807//regulation of synaptic vesicle priming;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035494//SNARE complex disassembly"	--
ENSG00000125815	0	0	0	0	0	0	0	0	0	0	0	0	CST8	cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0009986//cell surface	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000125816	0	0.028	0	0	0	0	0	1	0	0	0	0	NKX2-4	NK2 homeobox 4 [Source:HGNC Symbol;Acc:HGNC:7837]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0030154//cell differentiation"	Homeobox
ENSG00000125817	27.042	26.87	26.585	32.093	31.514	24.647	1621	1619	1177	1425	1596	1075	CENPB	centromere protein B [Source:HGNC Symbol;Acc:HGNC:1852]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0016604//nuclear body"	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003696//satellite DNA binding;GO:0019237//centromeric DNA binding;GO:0043565//sequence-specific DNA binding	-	--
ENSG00000125818	40.555	42.718	41.963	46.096	45.209	46.449	2366	2487	1848.06	2047	2259.13	2015.74	PSMF1	proteasome inhibitor subunit 1 [Source:HGNC Symbol;Acc:HGNC:9571]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K06700	GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0070628//proteasome binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010951//negative regulation of endopeptidase activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000125820	0	0.023	0	0	0	0	0	1	0	0	0	0	NKX2-2	NK2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7835]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08029	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0003323//type B pancreatic cell development;GO:0003326//pancreatic A cell fate commitment;GO:0003327//type B pancreatic cell fate commitment;GO:0003329//pancreatic PP cell fate commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007399//nervous system development;GO:0007420//brain development;GO:0009749//response to glucose;GO:0010628//positive regulation of gene expression;GO:0014003//oligodendrocyte development;GO:0014070//response to organic cyclic compound;GO:0021522//spinal cord motor neuron differentiation;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0021554//optic nerve development;GO:0030154//cell differentiation;GO:0031018//endocrine pancreas development;GO:0032570//response to progesterone;GO:0045597//positive regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0048565//digestive tract development;GO:0048665//neuron fate specification;GO:0048708//astrocyte differentiation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0060580//ventral spinal cord interneuron fate determination"	Homeobox
ENSG00000125821	4.704	5.296	5.79	5.095	4.97	4.257	368.67	406.52	330.46	280.73	317.58	238.43	DTD1	D-aminoacyl-tRNA deacylase 1 [Source:HGNC Symbol;Acc:HGNC:16219]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0051499//D-aminoacyl-tRNA deacylase activity;GO:0051500//D-tyrosyl-tRNA(Tyr) deacylase activity	GO:0006260//DNA replication;GO:0006399//tRNA metabolic process;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000125823	0	0	0	0	0	0	0	0	0	0	0	0	CSTL1	cystatin like 1 [Source:HGNC Symbol;Acc:HGNC:15958]	-	-	-	-	GO:0005576//extracellular region	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000125826	16.77	18.174	18.513	20.331	21.398	19.395	742	810	568	669	785	588	RBCK1	RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864]	Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Immune system;Cell growth and death	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis	K10630;K10630;K10630	GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0071797//LUBAC complex	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding	"GO:0000209//protein polyubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0042742//defense response to bacterium;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060546//negative regulation of necroptotic process;GO:0097039//protein linear polyubiquitination;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	Others
ENSG00000125827	26.254	23.903	22.076	19.823	22.806	23.53	2898	2596	1837	1738	2097	1784	TMX4	thioredoxin related transmembrane protein 4 [Source:HGNC Symbol;Acc:HGNC:25237]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000125831	0	0	0	0	0	0	0	0	0	0	0	0	CST11	cystatin 11 [Source:HGNC Symbol;Acc:HGNC:15959]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0036126//sperm flagellum;GO:0061827//sperm head	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030521//androgen receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000125834	4.963	5.101	4.803	4.155	4.984	4.847	666	688	476	413	565	449	STK35	serine/threonine kinase 35 [Source:HGNC Symbol;Acc:HGNC:16254]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051321//meiotic cell cycle	--
ENSG00000125835	44.077	48.602	47.666	50.76	47.718	52.38	979	1084.34	786	832	897	843	SNRPB	small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153]	Human Diseases;Genetic Information Processing	Immune disease;Transcription	ko05322//Systemic lupus erythematosus;ko03040//Spliceosome	K11086;K11086	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005683//U7 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071204//histone pre-mRNA 3'end processing complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0070034//telomerase RNA binding;GO:0071208//histone pre-mRNA DCP binding;GO:1990446//U1 snRNP binding;GO:1990447//U2 snRNP binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006479//protein methylation;GO:0007420//brain development;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000125841	34.733	35.191	34.565	38.011	37.946	40.923	1400	1421	1089	1209	1350	1209	NRSN2	neurensin 2 [Source:HGNC Symbol;Acc:HGNC:16229]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0008150//biological_process	--
ENSG00000125843	6.754	6.936	10.319	8.014	9.629	7.674	301	329	289	284	335	258	AP5S1	adaptor related protein complex 5 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:15875]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030119//AP-type membrane coat adaptor complex;GO:0031902//late endosome membrane;GO:0044599//AP-5 adaptor complex	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport	--
ENSG00000125844	139.55	151.145	125.671	103.076	113.148	115.503	9825	10225	6537	5401	6753	5737	RRBP1	ribosome binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10448]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14000	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005840//ribosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0038023//signaling receptor activity	GO:0001649//osteoblast differentiation;GO:0006412//translation;GO:0015031//protein transport	--
ENSG00000125845	11.75	11.244	13.534	15.129	13.457	16.018	864	831	735	824	836	857	BMP2	bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway;ko05217//Basal cell carcinoma	K21283;K21283;K21283;K21283;K21283	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0070724//BMP receptor complex	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0019211//phosphatase activator activity;GO:0039706//co-receptor binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046332//SMAD binding;GO:0048018//receptor ligand activity;GO:0070700//BMP receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001837//epithelial to mesenchymal transition;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002062//chondrocyte differentiation;GO:0003130//BMP signaling pathway involved in heart induction;GO:0003176//aortic valve development;GO:0003181//atrioventricular valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003210//cardiac atrium formation;GO:0003272//endocardial cushion formation;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0006029//proteoglycan metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007219//Notch signaling pathway;GO:0007267//cell-cell signaling;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0009887//animal organ morphogenesis;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010894//negative regulation of steroid biosynthetic process;GO:0010922//positive regulation of phosphatase activity;GO:0021537//telencephalon development;GO:0021978//telencephalon regionalization;GO:0030154//cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030282//bone mineralization;GO:0030335//positive regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031648//protein destabilization;GO:0032092//positive regulation of protein binding;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0033690//positive regulation of osteoblast proliferation;GO:0035051//cardiocyte differentiation;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0035630//bone mineralization involved in bone maturation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042482//positive regulation of odontogenesis;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0043065//positive regulation of apoptotic process;GO:0043407//negative regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0045165//cell fate commitment;GO:0045597//positive regulation of cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048711//positive regulation of astrocyte differentiation;GO:0048762//mesenchymal cell differentiation;GO:0048839//inner ear development;GO:0050790//regulation of catalytic activity;GO:0051042//negative regulation of calcium-independent cell-cell adhesion;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051148//negative regulation of muscle cell differentiation;GO:0051216//cartilage development;GO:0055007//cardiac muscle cell differentiation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060039//pericardium development;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060348//bone development;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0060485//mesenchyme development;GO:0060804//positive regulation of Wnt signaling pathway by BMP signaling pathway;GO:0061036//positive regulation of cartilage development;GO:0061312//BMP signaling pathway involved in heart development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071773//cellular response to BMP stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900745//positive regulation of p38MAPK cascade;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1905072//cardiac jelly development;GO:1905222//atrioventricular canal morphogenesis;GO:2000065//negative regulation of cortisol biosynthetic process;GO:2000726//negative regulation of cardiac muscle cell differentiation"	--
ENSG00000125846	6.145	5.496	5.038	3.303	4.633	4.709	231	242	165	117	180	160	ZNF133	zinc finger protein 133 [Source:HGNC Symbol;Acc:HGNC:12917]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000125848	17.674	15.207	14.701	10.797	9.647	12.673	1782	1545	1097	806	824	935	FLRT3	fibronectin leucine rich transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3762]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0031012//extracellular matrix;GO:0032584//growth cone membrane;GO:0042995//cell projection;GO:0043679//axon terminus;GO:0044295//axonal growth cone;GO:0097060//synaptic membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042803//protein homodimerization activity;GO:0045499//chemorepellent activity	GO:0003345//proepicardium cell migration involved in pericardium morphogenesis;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007507//heart development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0031175//neuron projection development;GO:0048598//embryonic morphogenesis;GO:0048678//response to axon injury;GO:0050808//synapse organization;GO:0050919//negative chemotaxis;GO:0051965//positive regulation of synapse assembly;GO:0060322//head development;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0099560//synaptic membrane adhesion;GO:1990138//neuron projection extension	--
ENSG00000125850	0	0	0	0	0	0.042	0	0	0	0	0	1	OVOL2	ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804]	-	-	-	-	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001755//neural crest cell migration;GO:0001842//neural fold formation;GO:0001947//heart looping;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0008544//epidermis development;GO:0009913//epidermal cell differentiation;GO:0009953//dorsal/ventral pattern formation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010837//regulation of keratinocyte proliferation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0045617//negative regulation of keratinocyte differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048557//embryonic digestive tract morphogenesis;GO:0051726//regulation of cell cycle;GO:0060214//endocardium formation;GO:0060347//heart trabecula formation;GO:0060390//regulation of SMAD protein signal transduction;GO:0060716//labyrinthine layer blood vessel development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000647//negative regulation of stem cell proliferation	zf-C2H2
ENSG00000125851	0.487	0.591	0.242	0.392	0.287	0.308	32	49	14	22	15	16	PCSK2	proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007399//nervous system development;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0016540//protein autoprocessing;GO:0030070//insulin processing;GO:0034230//enkephalin processing;GO:0034231//islet amyloid polypeptide processing	--
ENSG00000125861	0	0	0	0	0	0	0	0	0	0	0	0	GFRA4	GDNF family receptor alpha 4 [Source:HGNC Symbol;Acc:HGNC:13821]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043235//receptor complex	GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0038023//signaling receptor activity	GO:0007399//nervous system development;GO:0030279//negative regulation of ossification;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway	--
ENSG00000125863	9.845	8.221	8.524	7.303	7.033	10.313	641.61	515.13	386	339.11	352.06	459	MKKS	MKKS centrosomal shuttling protein [Source:HGNC Symbol;Acc:HGNC:7108]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:1902636//kinociliary basal body	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0051082//unfolded protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001947//heart looping;GO:0006457//protein folding;GO:0007286//spermatid development;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0007601//visual perception;GO:0007608//sensory perception of smell;GO:0008406//gonad development;GO:0010629//negative regulation of gene expression;GO:0014824//artery smooth muscle contraction;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030837//negative regulation of actin filament polymerization;GO:0032402//melanosome transport;GO:0032502//developmental process;GO:0033210//leptin-mediated signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0035176//social behavior;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0042311//vasodilation;GO:0044321//response to leptin;GO:0045444//fat cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0045776//negative regulation of blood pressure;GO:0046907//intracellular transport;GO:0048854//brain morphogenesis;GO:0050896//response to stimulus;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0051131//chaperone-mediated protein complex assembly;GO:0051216//cartilage development;GO:0051492//regulation of stress fiber assembly;GO:0051877//pigment granule aggregation in cell center;GO:0060027//convergent extension involved in gastrulation;GO:0060271//cilium assembly;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0060324//face development;GO:1905515//non-motile cilium assembly	--
ENSG00000125864	0.958	0.977	0.886	1.086	0.911	0.612	41	42	28	37	34	20	BFSP1	beaded filament structural protein 1 [Source:HGNC Symbol;Acc:HGNC:1040]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane	GO:0005200//structural constituent of cytoskeleton;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0008150//biological_process;GO:0045109//intermediate filament organization;GO:0048469//cell maturation;GO:0070307//lens fiber cell development	--
ENSG00000125868	112.141	101.898	97.729	87.456	74.143	80.249	3518	3270	2265	1989	1967	1841	DSTN	"destrin, actin depolymerizing factor [Source:HGNC Symbol;Acc:HGNC:15750]"	-	-	-	-	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030864//cortical actin cytoskeleton;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0008154//actin polymerization or depolymerization;GO:0030042//actin filament depolymerization;GO:0030043//actin filament fragmentation;GO:0030836//positive regulation of actin filament depolymerization;GO:0048870//cell motility;GO:0051014//actin filament severing	--
ENSG00000125869	0	0	0	0	0.063	0	0	0	0	0	2	0	LAMP5	lysosomal associated membrane protein family member 5 [Source:HGNC Symbol;Acc:HGNC:16097]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032584//growth cone membrane;GO:0032590//dendrite membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	-	GO:0072594//establishment of protein localization to organelle	--
ENSG00000125870	13.594	14.535	14.44	13.649	12.972	14.296	507	561	378	360	406	384	SNRPB2	small nuclear ribonucleoprotein polypeptide B2 [Source:HGNC Symbol;Acc:HGNC:11155]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11094	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0030532//small nuclear ribonucleoprotein complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030619//U1 snRNA binding;GO:0070990//snRNP binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000125871	6.069	6.171	5.33	4.836	4.615	4.63	279	281	180	165	178	154	MGME1	mitochondrial genome maintenance exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:16205]	-	-	-	-	GO:0005739//mitochondrion	GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008297//single-stranded DNA exodeoxyribonuclease activity;GO:0016787//hydrolase activity	GO:0000002//mitochondrial genome maintenance;GO:0006264//mitochondrial DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0043504//mitochondrial DNA repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000125872	1.873	1.111	1.579	6.231	7.038	6.457	114	68	71	281	362	286	LRRN4	leucine rich repeat neuronal 4 [Source:HGNC Symbol;Acc:HGNC:16208]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007616//long-term memory;GO:0008542//visual learning	--
ENSG00000125875	10.469	10.865	11.221	11.432	10.918	12.45	924	990	748	746	823	782	TBC1D20	TBC1 domain family member 20 [Source:HGNC Symbol;Acc:HGNC:16133]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031965//nuclear membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0001675//acrosome assembly;GO:0002088//lens development in camera-type eye;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0016192//vesicle-mediated transport;GO:0019068//virion assembly;GO:0034389//lipid droplet organization;GO:0043010//camera-type eye development;GO:0043547//positive regulation of GTPase activity;GO:0044829//positive regulation by host of viral genome replication;GO:0046726//positive regulation by virus of viral protein levels in host cell;GO:0070309//lens fiber cell morphogenesis;GO:0072520//seminiferous tubule development;GO:0090110//COPII-coated vesicle cargo loading;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport	--
ENSG00000125877	18.223	18.63	18.15	21.84	21.702	24.621	384	402	288	347	394	382	ITPA	inosine triphosphatase [Source:HGNC Symbol;Acc:HGNC:6176]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes	K01519;K01519;K01519	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004551//nucleotide diphosphatase activity;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0035870//dITP diphosphatase activity;GO:0036218//dTTP diphosphatase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity	GO:0006193//ITP catabolic process;GO:0009117//nucleotide metabolic process;GO:0009143//nucleoside triphosphate catabolic process;GO:0009204//deoxyribonucleoside triphosphate catabolic process;GO:0034404//nucleobase-containing small molecule biosynthetic process;GO:0051276//chromosome organization;GO:1901292//nucleoside phosphate catabolic process	--
ENSG00000125878	0	0	0	0	0	0	0	0	0	0	0	0	TCF15	transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11627]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043425//bHLH transcription factor binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding"	GO:0001756//somitogenesis;GO:0003016//respiratory system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007498//mesoderm development;GO:0007517//muscle organ development;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030154//cell differentiation;GO:0032502//developmental process;GO:0036342//post-anal tail morphogenesis;GO:0042755//eating behavior;GO:0043583//ear development;GO:0043588//skin development;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048339//paraxial mesoderm development;GO:0048644//muscle organ morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0050884//neuromuscular process controlling posture;GO:0060231//mesenchymal to epithelial transition;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:1903053//regulation of extracellular matrix organization;GO:2000738//positive regulation of stem cell differentiation	bHLH
ENSG00000125879	0.163	0	0	0	0	0.045	5	0	0	0	0	1	OTOR	otoraplin [Source:HGNC Symbol;Acc:HGNC:8517]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0001502//cartilage condensation;GO:0007605//sensory perception of sound	--
ENSG00000125885	0.962	0.666	0.308	0.4	0.396	0.444	97	70	29.46	35	39.26	37	MCM8	minichromosome maintenance 8 homologous recombination repair factor [Source:HGNC Symbol;Acc:HGNC:16147]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0042555//MCM complex;GO:0097362//MCM8-MCM9 complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0019899//enzyme binding;GO:0032406//MutLbeta complex binding;GO:0032407//MutSalpha complex binding;GO:0032408//MutSbeta complex binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007292//female gamete generation;GO:0032508//DNA duplex unwinding;GO:0036298//recombinational interstrand cross-link repair;GO:0048232//male gamete generation;GO:0050821//protein stabilization;GO:0071168//protein localization to chromatin	--
ENSG00000125888	0.282	0.077	0.181	0.209	0	0.184	3	1	1	2	0	1	BANF2	BANF family member 2 [Source:HGNC Symbol;Acc:HGNC:16172]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007059//chromosome segregation;GO:0030261//chromosome condensation	--
ENSG00000125895	0.362	0.077	0.346	0.301	0.26	0.316	13	3	9.94	8	7.87	8.26	TMEM74B	transmembrane protein 74B [Source:HGNC Symbol;Acc:HGNC:15893]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000125898	2.321	2.566	2.055	2.756	1.92	1.837	84	91	52	72	55	47	FAM110A	family with sequence similarity 110 member A [Source:HGNC Symbol;Acc:HGNC:16188]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000125900	0	0	0	0	0	0	0	0	0	0	0	0	SIRPD	signal regulatory protein delta [Source:HGNC Symbol;Acc:HGNC:16248]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	-	-	--
ENSG00000125901	18.649	21.386	21.331	25.048	21.512	23.217	393	453	332	391	383	356	MRPS26	mitochondrial ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:14045]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding	GO:0032543//mitochondrial translation	--
ENSG00000125903	0	0	0	0	0	0	0	0	0	0	0	0	DEFB129	defensin beta 129 [Source:HGNC Symbol;Acc:HGNC:16218]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium	--
ENSG00000125910	0.031	0	0	0	0	0.127	1	0	0	0	0	3	S1PR4	sphingosine-1-phosphate receptor 4 [Source:HGNC Symbol;Acc:HGNC:3170]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04068//FoxO signaling pathway;ko04071//Sphingolipid signaling pathway	K04293;K04293;K04293	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038036//sphingosine-1-phosphate receptor activity	GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019222//regulation of metabolic process	--
ENSG00000125912	16.081	16.968	15.523	21.204	21.73	18.005	1004	1092	807	917	1059	780	NCLN	nicalin [Source:HGNC Symbol;Acc:HGNC:26923]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0009966//regulation of signal transduction;GO:0043254//regulation of protein-containing complex assembly;GO:0050821//protein stabilization;GO:0061635//regulation of protein complex stability	--
ENSG00000125931	0.222	0.183	0.16	0.211	0.248	0	4.43	3.1	2	4	5.34	0	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 [Source:HGNC Symbol;Acc:HGNC:1986]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042803//protein homodimerization activity;GO:0050693//LBD domain binding;GO:0070410//co-SMAD binding	"GO:0001570//vasculogenesis;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006913//nucleocytoplasmic transport;GO:0006915//apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007420//brain development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030318//melanocyte differentiation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032868//response to insulin;GO:0034097//response to cytokine;GO:0034341//response to interferon-gamma;GO:0042438//melanin biosynthetic process;GO:0042981//regulation of apoptotic process;GO:0043473//pigmentation;GO:0043524//negative regulation of neuron apoptotic process;GO:0043627//response to estrogen;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051591//response to cAMP;GO:0060231//mesenchymal to epithelial transition;GO:0060395//SMAD protein signal transduction;GO:0060711//labyrinthine layer development;GO:0060712//spongiotrophoblast layer development;GO:0070555//response to interleukin-1;GO:0070669//response to interleukin-2;GO:0070670//response to interleukin-4;GO:0070741//response to interleukin-6;GO:0071104//response to interleukin-9;GO:0071105//response to interleukin-11;GO:0071107//response to parathyroid hormone;GO:0071559//response to transforming growth factor beta;GO:1902462//positive regulation of mesenchymal stem cell proliferation"	--
ENSG00000125944	66.131	68.645	65.181	55.547	61.102	58.431	3592	3551	2573	2068	2604	2282	HNRNPR	heterogeneous nuclear ribonucleoprotein R [Source:HGNC Symbol;Acc:HGNC:5047]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000125945	9.314	9.164	9.361	8.562	8.243	9.119	803	776	585	529	590	563	ZNF436	zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000125952	26.793	31.021	27.81	29.356	31.857	26.225	954.37	1094.34	759.27	773.03	865.32	669.93	MAX	MYC associated factor X [Source:HGNC Symbol;Acc:HGNC:6913]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko05222//Small cell lung cancer	K04453;K04453;K04453;K04453	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0030425//dendrite;GO:0032993//protein-DNA complex;GO:0042995//cell projection;GO:0070443//Mad-Max complex;GO:0071339//MLL1 complex;GO:0071943//Myc-Max complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009267//cellular response to starvation;GO:0010243//response to organonitrogen compound;GO:0010629//negative regulation of gene expression;GO:0032868//response to insulin;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048678//response to axon injury;GO:0051402//neuron apoptotic process;GO:0060041//retina development in camera-type eye;GO:0065003//protein-containing complex assembly;GO:0071375//cellular response to peptide hormone stimulus"	bHLH
ENSG00000125954	0.269	0.306	0.395	0.146	0.745	0	10.31	9.37	8.88	3.3	22.5	0	CHURC1-FNTB	CHURC1-FNTB readthrough [Source:HGNC Symbol;Acc:HGNC:42960]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K05954	GO:0005965//protein farnesyltransferase complex	GO:0003824//catalytic activity;GO:0004659//prenyltransferase activity;GO:0004660//protein farnesyltransferase activity;GO:0008270//zinc ion binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	"GO:0007275//multicellular organism development;GO:0018343//protein farnesylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000125962	4.583	4.666	4.677	3.36	3.969	3.825	259	265	195	143	194	163	ARMCX5	armadillo repeat containing X-linked 5 [Source:HGNC Symbol;Acc:HGNC:25772]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000125965	0.733	0.952	0.441	0.687	0.699	0.476	36	47	16	25	29	17	GDF5	growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K04664;K04664;K04664	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0036122//BMP binding;GO:0042802//identical protein binding	GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009612//response to mechanical stimulus;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0040014//regulation of multicellular organism growth;GO:0043524//negative regulation of neuron apoptotic process;GO:0043932//ossification involved in bone remodeling;GO:0045666//positive regulation of neuron differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0060390//regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0060591//chondroblast differentiation;GO:2001054//negative regulation of mesenchymal cell apoptotic process	--
ENSG00000125966	3.032	3.043	1.692	3.094	3.368	3.215	275.19	277.58	113.42	208.03	258.25	212.33	MMP24	matrix metallopeptidase 24 [Source:HGNC Symbol;Acc:HGNC:7172]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K08002	GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0032588//trans-Golgi network membrane;GO:0070062//extracellular exosome	GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0010001//glial cell differentiation;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0050790//regulation of catalytic activity;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0097150//neuronal stem cell population maintenance;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000125967	7.15	8.627	7.485	9.786	10.593	9.477	270	289	213	289	293	265	NECAB3	N-terminal EF-hand calcium binding protein 3 [Source:HGNC Symbol;Acc:HGNC:15851]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0009306//protein secretion;GO:0019538//protein metabolic process;GO:0042984//regulation of amyloid precursor protein biosynthetic process	--
ENSG00000125968	40.802	38.272	34.688	56.413	58.951	63.022	840	791	527	855	1021	942	ID1	"inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360]"	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signal transduction;Signal transduction;Cellular community - eukaryotes;Signal transduction	ko04015//Rap1 signaling pathway;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04680;K04680;K04680;K04680	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0047485//protein N-terminus binding;GO:0070628//proteasome binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007420//brain development;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0010628//positive regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032922//circadian regulation of gene expression;GO:0036164//cell-abiotic substrate adhesion;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043534//blood vessel endothelial cell migration;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0048514//blood vessel morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050774//negative regulation of dendrite morphogenesis;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901342//regulation of vasculature development;GO:1901653//cellular response to peptide;GO:1903351//cellular response to dopamine;GO:1990090//cellular response to nerve growth factor stimulus"	bHLH
ENSG00000125970	99.767	94.738	119.239	121.759	103.468	115.982	2983	2952	2568	2699	2700	2543	RALY	RALY heterogeneous nuclear ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15921]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0042632//cholesterol homeostasis;GO:1903506//regulation of nucleic acid-templated transcription"	--
ENSG00000125971	108.446	108.368	132.338	120.76	114.59	138.406	1490.56	1497.82	1343.53	1228.64	1331.45	1383.15	DYNLRB1	dynein light chain roadblock-type 1 [Source:HGNC Symbol;Acc:HGNC:15468]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K10419	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0016020//membrane;GO:0030286//dynein complex;GO:0097542//ciliary tip	GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement;GO:0007632//visual behavior;GO:0009416//response to light stimulus	--
ENSG00000125975	0	0	0	0	0	0	0	0	0	0	0	0	C20orf173	chromosome 20 open reading frame 173 [Source:HGNC Symbol;Acc:HGNC:16166]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000125977	21.918	20.905	19.461	16.959	15.316	27.479	1162	1114	762	666	686	1060	EIF2S2	eukaryotic translation initiation factor 2 subunit beta [Source:HGNC Symbol;Acc:HGNC:3266]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005850//eukaryotic translation initiation factor 2 complex	"GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0031369//translation initiation factor binding;GO:0046872//metal ion binding"	GO:0001701//in utero embryonic development;GO:0001731//formation of translation preinitiation complex;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002176//male germ cell proliferation;GO:0006412//translation;GO:0006413//translational initiation;GO:0008584//male gonad development	--
ENSG00000125991	195.85	210.57	214.688	230.068	214.343	201.315	5241	5675	4193	4580	4848	3910	ERGIC3	ERGIC and golgi 3 [Source:HGNC Symbol;Acc:HGNC:15927]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding;GO:0043621//protein self-association	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0016192//vesicle-mediated transport;GO:0090316//positive regulation of intracellular protein transport"	--
ENSG00000125995	15.637	17.48	21.054	20.79	14.964	16.813	127	142	126	127	102	99	ROMO1	reactive oxygen species modulator 1 [Source:HGNC Symbol;Acc:HGNC:16185]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0008284//positive regulation of cell population proliferation;GO:0030150//protein import into mitochondrial matrix;GO:0031640//killing of cells of other organism;GO:0034614//cellular response to reactive oxygen species;GO:0042742//defense response to bacterium;GO:0045039//protein insertion into mitochondrial inner membrane;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051838//cytolysis by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090399//replicative senescence;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000125998	0	0	0	0	0	0	0	0	0	0	0	0	FAM83C	family with sequence similarity 83 member C [Source:HGNC Symbol;Acc:HGNC:16121]	-	-	-	-	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007165//signal transduction	--
ENSG00000125999	2.615	2.952	2.039	1.47	1.454	1.736	89	101	48	36	40	43	BPIFB1	BPI fold containing family B member 1 [Source:HGNC Symbol;Acc:HGNC:16108]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0008289//lipid binding	GO:0002227//innate immune response in mucosa;GO:0002376//immune system process;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0045087//innate immune response	--
ENSG00000126001	8.438	9.294	10.14	6.069	8.972	6.001	777	854	657	480	610	551	CEP250	centrosomal protein 250 [Source:HGNC Symbol;Acc:HGNC:1859]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0032991//protein-containing complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0008104//protein localization;GO:0010457//centriole-centriole cohesion;GO:0030030//cell projection organization;GO:0030997//regulation of centriole-centriole cohesion;GO:0033365//protein localization to organelle;GO:0050908//detection of light stimulus involved in visual perception;GO:0060271//cilium assembly;GO:1904781//positive regulation of protein localization to centrosome;GO:1905515//non-motile cilium assembly	--
ENSG00000126003	7.152	7.157	7.56	7.514	6.851	7.392	839	844	655	653	679	631	PLAGL2	PLAG1 like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:9047]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0009791//post-embryonic development;GO:0034378//chylomicron assembly;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	zf-C2H2
ENSG00000126005	32.766	37.781	36.51	34.669	28.456	26.223	882.81	979.42	724.58	717.97	647.75	494.67	MMP24OS	MMP24 opposite strand [Source:HGNC Symbol;Acc:HGNC:44421]	-	-	-	-	-	-	-	--
ENSG00000126010	0.638	0.536	0.324	0.485	0.283	0.576	32	27	12	18	12	21	GRPR	gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04169;K04169	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008188//neuropeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007611//learning or memory;GO:0035176//social behavior;GO:0036343//psychomotor behavior;GO:0042127//regulation of cell population proliferation;GO:0043207//response to external biotic stimulus;GO:0061744//motor behavior	--
ENSG00000126012	21.566	22.189	25.771	23.901	23.585	23.827	2366	2413	2102	1930	2151	1884	KDM5C	lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0034647//histone H3-tri/di/monomethyl-lysine-4 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0009636//response to toxic substance;GO:0032259//methylation;GO:0034720//histone H3-K4 demethylation;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0070076//histone lysine demethylation"	--
ENSG00000126016	7.396	7.369	7.244	7.044	8.238	7.445	1114	1156	830	809	960	833	AMOT	angiomotin [Source:HGNC Symbol;Acc:HGNC:17810]	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04530//Tight junction;ko04390//Hippo signaling pathway	K16819;K16819	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0008180//COP9 signalosome;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0043532//angiostatin binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001702//gastrulation with mouth forming second;GO:0003365//establishment of cell polarity involved in ameboidal cell migration;GO:0006935//chemotaxis;GO:0007043//cell-cell junction assembly;GO:0016525//negative regulation of angiogenesis;GO:0030036//actin cytoskeleton organization;GO:0030334//regulation of cell migration;GO:0034260//negative regulation of GTPase activity;GO:0034613//cellular protein localization;GO:0035329//hippo signaling;GO:0040019//positive regulation of embryonic development;GO:0042074//cell migration involved in gastrulation;GO:0043116//negative regulation of vascular permeability;GO:0043534//blood vessel endothelial cell migration;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045793//positive regulation of cell size;GO:0048514//blood vessel morphogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051496//positive regulation of stress fiber assembly	--
ENSG00000126062	34.414	36.446	34.978	38.459	40.381	40.725	1504	1601	1129	1245	1491	1295	TMEM115	transmembrane protein 115 [Source:HGNC Symbol;Acc:HGNC:30055]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017119//Golgi transport complex;GO:0032580//Golgi cisterna membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0008285//negative regulation of cell population proliferation;GO:0015031//protein transport"	--
ENSG00000126067	12.951	13.124	13.436	14.867	14.389	15.12	1189	1211	911	1011	1116	1010	PSMB2	proteasome 20S subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:9539]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02734;K02734;K02734;K02734;K02734;K02734;K02734;K02734	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0016020//membrane;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome"	GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010243//response to organonitrogen compound;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0014070//response to organic cyclic compound;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000126070	3.319	2.829	3.467	1.582	3.444	2.379	430	294	209	176	262	235	AGO3	argonaute RISC catalytic component 3 [Source:HGNC Symbol;Acc:HGNC:18421]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K11593	GO:0000794//condensed nuclear chromosome;GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070578//RISC-loading complex	"GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003743//translation initiation factor activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0090624//endoribonuclease activity, cleaving miRNA-paired mRNA"	"GO:0006402//mRNA catabolic process;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0010501//RNA secondary structure unwinding;GO:0010628//positive regulation of gene expression;GO:0016246//RNA interference;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0035279//mRNA cleavage involved in gene silencing by miRNA;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0072091//regulation of stem cell proliferation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1901224//positive regulation of NIK/NF-kappaB signaling"	--
ENSG00000126088	49	53.51	59.648	56.948	53.767	58.327	1206.03	1318.15	1081.02	1031.02	1105.02	1040.03	UROD	uroporphyrinogen decarboxylase [Source:HGNC Symbol;Acc:HGNC:12591]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01599;K01599	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004853//uroporphyrinogen decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0042168//heme metabolic process	--
ENSG00000126091	10.826	11.164	10.591	10.519	11.572	10.457	428	416.24	312	357.66	407	322	ST3GAL3	"ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:10866]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K00781;K00781;K00781;K00781;K00781;K00781	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0005515//protein binding;GO:0008118//N-acetyllactosaminide alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006486//protein glycosylation;GO:0009312//oligosaccharide biosynthetic process;GO:0010706//ganglioside biosynthetic process via lactosylceramide;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0019082//viral protein processing;GO:0097503//sialylation	--
ENSG00000126106	8.106	7.065	11.062	11.743	10.969	15.235	261.7	220.38	230.2	274.46	289.68	327.94	TMEM53	transmembrane protein 53 [Source:HGNC Symbol;Acc:HGNC:26186]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000126107	11.942	12.586	12.97	12.883	12.26	13.295	890.97	943.85	701.98	711.98	768.98	689.97	HECTD3	HECT domain E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:26117]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019905//syntaxin binding	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000126214	33.764	32.292	29.823	27.366	31.969	29.489	1615.07	1515.5	1083.34	949.99	1263	1026.29	KLC1	kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection	K10407;K10407;K10407;K10407;K10407;K10407;K10407	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0003774//cytoskeletal motor activity;GO:0005515//protein binding	GO:0035617//stress granule disassembly	--
ENSG00000126215	6.911	7.168	7.266	5.033	5.311	3.894	237.23	233.96	176.39	150.01	184	113.71	XRCC3	X-ray repair cross complementing 3 [Source:HGNC Symbol;Acc:HGNC:12830]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10880	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0033065//Rad51C-XRCC3 complex;GO:0048471//perinuclear region of cytoplasm"	"GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008821//crossover junction endodeoxyribonuclease activity"	GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010033//response to organic substance;GO:0010824//regulation of centrosome duplication;GO:0036297//interstrand cross-link repair;GO:0045003//double-strand break repair via synthesis-dependent strand annealing;GO:0071140//resolution of mitotic recombination intermediates;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0090656//t-circle formation;GO:0090657//telomeric loop disassembly;GO:0090737//telomere maintenance via telomere trimming	--
ENSG00000126216	5.715	5.504	5.651	5.154	5.669	6.817	430	422	331	284	370	357	TUBGCP3	tubulin gamma complex associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18598]	-	-	-	-	GO:0000922//spindle pole;GO:0000923//equatorial microtubule organizing center;GO:0000930//gamma-tubulin complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005827//polar microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0008275//gamma-tubulin small complex;GO:0016020//membrane	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0007338//single fertilization;GO:0031122//cytoplasmic microtubule organization;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle	--
ENSG00000126217	17.296	17.128	13.437	10.219	11.897	10.527	1196	1291	710	541	720	567	MCF2L	MCF.2 cell line derived transforming sequence like [Source:HGNC Symbol;Acc:HGNC:14576]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0019898//extrinsic component of membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding	GO:0035025//positive regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000126218	0.233	0.375	0.429	0.466	0.546	0.132	7	12	10	11	14	3	F10	coagulation factor X [Source:HGNC Symbol;Acc:HGNC:3528]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01314	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031233//intrinsic component of external side of plasma membrane	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030335//positive regulation of cell migration;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000126226	10.945	10.422	10.636	10.005	10.531	11.199	411	401	300	282	335	308	PCID2	PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0044615//nuclear pore nuclear basket;GO:0070390//transcription export complex 2	GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000973//posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0043066//negative regulation of apoptotic process;GO:0043488//regulation of mRNA stability;GO:0045579//positive regulation of B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0051028//mRNA transport;GO:0071028//nuclear mRNA surveillance;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:2000117//negative regulation of cysteine-type endopeptidase activity"	--
ENSG00000126231	0	0.032	0	0.043	0	0	0	1	0	1	0	0	PROZ	"protein Z, vitamin K dependent plasma glycoprotein [Source:HGNC Symbol;Acc:HGNC:9460]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007599//hemostasis	--
ENSG00000126233	0	0	0	0	0	0	0	0	0	0	0	0	SLURP1	secreted LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18746]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23681	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0030549//acetylcholine receptor activator activity	GO:0001775//cell activation;GO:0007155//cell adhesion;GO:0007626//locomotory behavior;GO:0008285//negative regulation of cell population proliferation;GO:0010839//negative regulation of keratinocyte proliferation;GO:0030336//negative regulation of cell migration;GO:0038195//urokinase plasminogen activator signaling pathway;GO:0050884//neuromuscular process controlling posture	--
ENSG00000126243	7.457	8.214	8.45	8.377	9.421	8.605	609	671	516	505	629	513	LRFN3	leucine rich repeat and fibronectin type III domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28370]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0099179//regulation of synaptic membrane adhesion;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000126246	0.4	1.274	0.337	0.811	0.381	0.756	12.19	12.69	6.37	16.82	5.73	14.21	IGFLR1	IGF like family receptor 1 [Source:HGNC Symbol;Acc:HGNC:23620]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000126247	253.42	266.957	273.166	328.657	301.383	274.327	4773	5153	3846	4656	4949	3770	CAPNS1	calpain small subunit 1 [Source:HGNC Symbol;Acc:HGNC:1481]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K08583	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0110158//calpain complex	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008284//positive regulation of cell population proliferation;GO:0016241//regulation of macroautophagy	--
ENSG00000126249	3.929	5.431	5.586	5.288	3.65	4.982	94.3	131	99	94	74	87	PDCD2L	programmed cell death 2 like [Source:HGNC Symbol;Acc:HGNC:28194]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding	GO:0007049//cell cycle	--
ENSG00000126251	0	0	0	0	0	0	0	0	0	0	0	0	GPR42	G protein-coupled receptor 42 [Source:HGNC Symbol;Acc:HGNC:4500]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000126254	34.221	33.895	34.888	43.173	38.029	40.091	1126	1126	850	1063	1051	949	RBM42	RNA binding motif protein 42 [Source:HGNC Symbol;Acc:HGNC:28117]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000126259	0.754	0.926	0.59	1.154	1.524	1.337	46	55	25	50	77	59	KIRREL2	kirre like nephrin family adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:18816]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036057//slit diaphragm	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding	GO:0001933//negative regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000126261	39.116	35.962	33.56	29.699	34.658	25.874	1658	1494	1025	873	1069	970	UBA2	ubiquitin like modifier activating enzyme 2 [Source:HGNC Symbol;Acc:HGNC:30661]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10685	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031510//SUMO activating enzyme complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016740//transferase activity;GO:0019948//SUMO activating enzyme activity;GO:0032183//SUMO binding;GO:0044388//small protein activating enzyme binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0016925//protein sumoylation;GO:0032446//protein modification by small protein conjugation;GO:0033235//positive regulation of protein sumoylation	--
ENSG00000126262	0	0	0	0	0	0	0	0	0	0	0	0	FFAR2	free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K04328	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002376//immune system process;GO:0002385//mucosal immune response;GO:0002673//regulation of acute inflammatory response;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0002879//positive regulation of acute inflammatory response to non-antigenic stimulus;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0019915//lipid storage;GO:0032722//positive regulation of chemokine production;GO:0032757//positive regulation of interleukin-8 production;GO:0042593//glucose homeostasis;GO:0045444//fat cell differentiation;GO:0071398//cellular response to fatty acid;GO:0090276//regulation of peptide hormone secretion	--
ENSG00000126264	0.085	0	0	0.115	0.101	0	1	0	0	1	1	0	HCST	hematopoietic cell signal transducer [Source:HGNC Symbol;Acc:HGNC:16977]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07988	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0043548//phosphatidylinositol 3-kinase binding	GO:0006468//protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0050776//regulation of immune response	--
ENSG00000126266	0	0	0	0.012	0	0	0	0	0	1	0	0	FFAR1	free fatty acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:4498]	Organismal Systems	Endocrine system	ko04911//Insulin secretion	K04325	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030073//insulin secretion;GO:0032024//positive regulation of insulin secretion;GO:0032691//negative regulation of interleukin-1 beta production;GO:0042593//glucose homeostasis;GO:0051928//positive regulation of calcium ion transport;GO:0070542//response to fatty acid	--
ENSG00000126267	118.877	119.224	121.86	129.906	102.202	134.656	1200	1213	911	974	874	984	COX6B1	cytochrome c oxidase subunit 6B1 [Source:HGNC Symbol;Acc:HGNC:2280]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV	GO:0004129//cytochrome-c oxidase activity	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0021762//substantia nigra development;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000126337	0	0	0	0	0	0	0	0	0	0	0	0	KRT36	keratin 36 [Source:HGNC Symbol;Acc:HGNC:6454]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0008150//biological_process;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization;GO:0045616//regulation of keratinocyte differentiation	--
ENSG00000126351	35.623	33.13	37.284	46.139	38.862	42.315	2164.74	1993.56	1724.24	2126.35	2021.57	1898.69	THRA	thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04919//Thyroid hormone signaling pathway	K05547;K05547	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017025//TBP-class protein binding;GO:0019904//protein domain specific binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0070324//thyroid hormone binding;GO:0140296//general transcription initiation factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0002154//thyroid hormone mediated signaling pathway;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0002157//positive regulation of thyroid hormone mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007611//learning or memory;GO:0008016//regulation of heart contraction;GO:0008050//female courtship behavior;GO:0009409//response to cold;GO:0009755//hormone-mediated signaling pathway;GO:0009887//animal organ morphogenesis;GO:0017055//negative regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0030878//thyroid gland development;GO:0033032//regulation of myeloid cell apoptotic process;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045925//positive regulation of female receptivity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050994//regulation of lipid catabolic process;GO:0060509//type I pneumocyte differentiation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2000143//negative regulation of DNA-templated transcription, initiation"	THR-like
ENSG00000126353	0	0	0	0	0	0.03	0	0	0	0	0	1	CCR7	C-C motif chemokine receptor 7 [Source:HGNC Symbol;Acc:HGNC:1608]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04182;K04182;K04182	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0035757//chemokine (C-C motif) ligand 19 binding;GO:0035758//chemokine (C-C motif) ligand 21 binding;GO:0038117//C-C motif chemokine 19 receptor activity;GO:0038121//C-C motif chemokine 21 receptor activity	GO:0001768//establishment of T cell polarity;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002407//dendritic cell chemotaxis;GO:0002408//myeloid dendritic cell chemotaxis;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0002885//positive regulation of hypersensitivity;GO:0002922//positive regulation of humoral immune response;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0031529//ruffle organization;GO:0032496//response to lipopolysaccharide;GO:0032649//regulation of interferon-gamma production;GO:0032651//regulation of interleukin-1 beta production;GO:0032695//negative regulation of interleukin-12 production;GO:0032735//positive regulation of interleukin-12 production;GO:0034695//response to prostaglandin E;GO:0038115//chemokine (C-C motif) ligand 19 signaling pathway;GO:0038116//chemokine (C-C motif) ligand 21 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045060//negative thymic T cell selection;GO:0045785//positive regulation of cell adhesion;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0048872//homeostasis of number of cells;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051491//positive regulation of filopodium assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071345//cellular response to cytokine stimulus;GO:0071731//response to nitric oxide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090630//activation of GTPase activity;GO:0097022//lymphocyte migration into lymph node;GO:0097029//mature conventional dendritic cell differentiation;GO:2000147//positive regulation of cell motility;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:2000522//positive regulation of immunological synapse formation;GO:2000525//positive regulation of T cell costimulation;GO:2000526//positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation;GO:2000547//regulation of dendritic cell dendrite assembly;GO:2000669//negative regulation of dendritic cell apoptotic process	--
ENSG00000126368	5.211	4.987	6.125	6.549	6.367	6.76	284.26	273.44	246.76	264.65	293.43	268.31	NR1D1	nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K03728	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0020037//heme binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001678//cellular glucose homeostasis;GO:0005978//glycogen biosynthetic process;GO:0006355//regulation of transcription, DNA-templated;GO:0007623//circadian rhythm;GO:0009755//hormone-mediated signaling pathway;GO:0010498//proteasomal protein catabolic process;GO:0019216//regulation of lipid metabolic process;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0031648//protein destabilization;GO:0032922//circadian regulation of gene expression;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0042632//cholesterol homeostasis;GO:0042749//regulation of circadian sleep/wake cycle;GO:0042752//regulation of circadian rhythm;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043401//steroid hormone mediated signaling pathway;GO:0044321//response to leptin;GO:0045598//regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0050728//negative regulation of inflammatory response;GO:0060086//circadian temperature homeostasis;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0061889//negative regulation of astrocyte activation;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0120163//negative regulation of cold-induced thermogenesis;GO:0150079//negative regulation of neuroinflammatory response;GO:1903979//negative regulation of microglial cell activation"	THR-like
ENSG00000126391	5.246	6.508	4.925	5.882	6.408	5.997	401	441	278	333	353	296	FRMD8	FERM domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25462]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0032760//positive regulation of tumor necrosis factor production;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000126432	194.052	194.585	213.515	247.055	212.828	223.519	3385	3384	2752	3205	3139	2825	PRDX5	peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K11187	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0001016//RNA polymerase III transcription regulatory region sequence-specific DNA binding;GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0051920//peroxiredoxin activity	GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0016480//negative regulation of transcription by RNA polymerase III;GO:0034599//cellular response to oxidative stress;GO:0034614//cellular response to reactive oxygen species;GO:0042744//hydrogen peroxide catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045454//cell redox homeostasis;GO:0098869//cellular oxidant detoxification	--
ENSG00000126453	5.35	5.644	7.063	7.038	6.544	5.073	113.71	123.49	107.19	116.58	125.98	73.23	BCL2L12	BCL2 like 12 [Source:HGNC Symbol;Acc:HGNC:13787]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane	GO:0002039//p53 binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000773//negative regulation of cellular senescence;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000126456	23.847	23.779	26.419	27.387	23.409	28.603	675.29	679.51	577.81	569.42	583.04	589.77	IRF3	interferon regulatory factor 3 [Source:HGNC Symbol;Acc:HGNC:6118]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04620//Toll-like receptor signaling pathway;ko05133//Pertussis;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411;K05411	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0009617//response to bacterium;GO:0010468//regulation of gene expression;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0039530//MDA-5 signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0051607//defense response to virus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071360//cellular response to exogenous dsRNA;GO:0071888//macrophage apoptotic process;GO:0097300//programmed necrotic cell death;GO:0098586//cellular response to virus"	IRF
ENSG00000126457	63.915	61.526	63.065	73.31	69.807	78.944	1822	1755	1335	1552	1686	1634	PRMT1	protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5187]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04068//FoxO signaling pathway;ko04922//Glucagon signaling pathway	K11434;K11434	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034709//methylosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0008327//methyl-CpG binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042802//identical protein binding;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0048273//mitogen-activated protein kinase p38 binding;GO:1904047//S-adenosyl-L-methionine binding	"GO:0001701//in utero embryonic development;GO:0006325//chromatin organization;GO:0006479//protein methylation;GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019082//viral protein processing;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0031175//neuron projection development;GO:0032259//methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0035247//peptidyl-arginine omega-N-methylation;GO:0043985//histone H4-R3 methylation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045652//regulation of megakaryocyte differentiation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0046329//negative regulation of JNK cascade;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048738//cardiac muscle tissue development;GO:0051260//protein homooligomerization;GO:1900745//positive regulation of p38MAPK cascade"	--
ENSG00000126458	15.549	15.275	15.359	13.796	14.7	9.274	318	314	232	209	254	138	RRAS	RAS related [Source:HGNC Symbol;Acc:HGNC:10447]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Infectious disease: bacterial;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cancer: overview;Development and regeneration;Cell growth and death;Transport and catabolism;Signal transduction;Immune system;Transport and catabolism	ko04010//MAPK signaling pathway;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04137//Mitophagy - animal	K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829;K07829	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0044877//protein-containing complex binding	GO:0002521//leukocyte differentiation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0030336//negative regulation of cell migration;GO:0045766//positive regulation of angiogenesis;GO:0051896//regulation of protein kinase B signaling;GO:0060325//face morphogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:1904906//positive regulation of endothelial cell-matrix adhesion via fibronectin;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000126460	0.034	0.103	0.248	0.706	0.203	0	1	3	2	5	5	0	PRRG2	proline rich and Gla domain 2 [Source:HGNC Symbol;Acc:HGNC:9470]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000126461	14.777	16.395	16.095	21.271	18.43	16.366	1089	1275	1041	1193	1247	917	SCAF1	SR-related CTD associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30403]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0099122//RNA polymerase II C-terminal domain binding	GO:0006366//transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000126464	5.11	5.924	6.399	6.091	6.741	7.291	786	916	727	694	876	816	PRR12	proline rich 12 [Source:HGNC Symbol;Acc:HGNC:29217]	-	-	-	-	GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse	-	-	--
ENSG00000126467	0	0	0	0	0	0	0	0	0	0	0	0	TSKS	testis specific serine kinase substrate [Source:HGNC Symbol;Acc:HGNC:30719]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019901//protein kinase binding	-	--
ENSG00000126500	13.167	14.133	9.925	7.851	9.65	6.71	1105	1203	616	492	687	410	FLRT1	fibronectin leucine rich transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3760]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000126522	11.481	6.107	7.137	9.54	8.728	7.253	179.4	198	164.19	235.38	238.34	169.63	ASL	argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis"	K01755;K01755;K01755;K01755	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004056//argininosuccinate lyase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0042802//identical protein binding	GO:0000050//urea cycle;GO:0006526//arginine biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0042450//arginine biosynthetic process via ornithine	--
ENSG00000126524	44.961	41.805	40.245	38.098	35.725	42.1	1502	1405	994	943	1009	1023	SBDS	SBDS ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:19440]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14574	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019843//rRNA binding;GO:0043022//ribosome binding	GO:0001833//inner cell mass cell proliferation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006364//rRNA processing;GO:0007052//mitotic spindle organization;GO:0030282//bone mineralization;GO:0030595//leukocyte chemotaxis;GO:0042254//ribosome biogenesis;GO:0042256//mature ribosome assembly;GO:0048539//bone marrow development	--
ENSG00000126545	0	0	0	0	0	0	0	0	0	0	0	0	CSN1S1	casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:1903494//response to dehydroepiandrosterone;GO:1903496//response to 11-deoxycorticosterone	--
ENSG00000126549	0.213	0	0	0	0	0	3	0	0	0	0	0	STATH	statherin [Source:HGNC Symbol;Acc:HGNC:11369]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13914	GO:0005576//extracellular region	"GO:0005515//protein binding;GO:0030197//extracellular matrix constituent, lubricant activity;GO:0030345//structural constituent of tooth enamel;GO:0046848//hydroxyapatite binding"	GO:0001503//ossification;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0042742//defense response to bacterium;GO:0046541//saliva secretion	--
ENSG00000126550	0	0	0	0	0.313	0	0	0	0	0	3	0	HTN1	histatin 1 [Source:HGNC Symbol;Acc:HGNC:5283]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13913	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0031214//biomineral tissue development;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050832//defense response to fungus	--
ENSG00000126561	3.809	3.885	4.192	4.584	4.751	3.937	294.06	299.25	235.43	262.24	311.89	220.57	STAT5A	signal transducer and activator of transcription 5A [Source:HGNC Symbol;Acc:HGNC:11366]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: overview;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Endocrine system;Immune system;Endocrine and metabolic disease;Immune system;Signal transduction;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05162//Measles;ko04935//Growth hormone synthesis, secretion and action;ko04659//Th17 cell differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04658//Th1 and Th2 cell differentiation;ko04012//ErbB signaling pathway;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia"	K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223;K11223	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0001938//positive regulation of endothelial cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007595//lactation;GO:0019221//cytokine-mediated signaling pathway;GO:0019530//taurine metabolic process;GO:0038026//reelin-mediated signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0071310//cellular response to organic substance"	STAT
ENSG00000126562	0.126	0.025	0.132	0.017	0.014	0.017	11	2	8.48	1	1	1	WNK4	WNK lysine deficient protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:14544]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019869//chloride channel inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0008104//protein localization;GO:0010766//negative regulation of sodium ion transport;GO:0016310//phosphorylation;GO:0030003//cellular cation homeostasis;GO:0035556//intracellular signal transduction;GO:0050801//ion homeostasis;GO:0070294//renal sodium ion absorption;GO:0072156//distal tubule morphogenesis;GO:0090188//negative regulation of pancreatic juice secretion;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000126581	34.421	36.864	31.953	33.012	35.024	36.181	1482.79	1518.19	1003.07	1012.23	1231.56	1128.2	BECN1	beclin 1 [Source:HGNC Symbol;Acc:HGNC:1034]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Neurodegenerative disease;Signal transduction;Transport and catabolism;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04136//Autophagy - other;ko04215//Apoptosis - multiple species	K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334	"GO:0000407//phagophore assembly site;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0019898//extrinsic component of membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0034271//phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272//phosphatidylinositol 3-kinase complex, class III, type II;GO:0035032//phosphatidylinositol 3-kinase complex, class III;GO:0045335//phagocytic vesicle"	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0051020//GTPase binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0001666//response to hypoxia;GO:0006468//protein phosphorylation;GO:0006622//protein targeting to lysosome;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006968//cellular defense response;GO:0006995//cellular response to nitrogen starvation;GO:0007040//lysosome organization;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007568//aging;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010040//response to iron(II) ion;GO:0010288//response to lead ion;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016236//macroautophagy;GO:0016241//regulation of macroautophagy;GO:0031667//response to nutrient levels;GO:0032465//regulation of cytokinesis;GO:0032801//receptor catabolic process;GO:0033197//response to vitamin E;GO:0033554//cellular response to stress;GO:0034198//cellular response to amino acid starvation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0042149//cellular response to glucose starvation;GO:0043066//negative regulation of apoptotic process;GO:0043652//engulfment of apoptotic cell;GO:0045022//early endosome to late endosome transport;GO:0045324//late endosome to vacuole transport;GO:0048583//regulation of response to stimulus;GO:0048666//neuron development;GO:0050435//amyloid-beta metabolic process;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051607//defense response to virus;GO:0051707//response to other organism;GO:0060548//negative regulation of cell death;GO:0070301//cellular response to hydrogen peroxide;GO:0071275//cellular response to aluminum ion;GO:0071280//cellular response to copper ion;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0097352//autophagosome maturation;GO:0098780//response to mitochondrial depolarisation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1902902//negative regulation of autophagosome assembly;GO:1905672//negative regulation of lysosome organization;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000786//positive regulation of autophagosome assembly;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000126583	0.433	0.08	0.085	0.195	0.145	0.111	12	5	3	9	8	5	PRKCG	protein kinase C gamma [Source:HGNC Symbol;Acc:HGNC:9402]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Endocrine system;Nervous system;Neurodegenerative disease;Circulatory system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Cancer: overview;Digestive system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Substance dependence;Cellular community - eukaryotes;Nervous system;Endocrine system;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Digestive system;Cancer: specific types;Endocrine system;Substance dependence;Nervous system;Endocrine system;Signal transduction;Nervous system;Excretory system;Excretory system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04650//Natural killer cell mediated cytotoxicity;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko05231//Choline metabolism in cancer;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko04971//Gastric acid secretion;ko05223//Non-small cell lung cancer;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04960//Aldosterone-regulated sodium reabsorption"	K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663;K19663	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007268//chemical synaptic transmission;GO:0007611//learning or memory;GO:0007635//chemosensory behavior;GO:0009636//response to toxic substance;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031397//negative regulation of protein ubiquitination;GO:0032095//regulation of response to food;GO:0032425//positive regulation of mismatch repair;GO:0035556//intracellular signal transduction;GO:0042177//negative regulation of protein catabolic process;GO:0042752//regulation of circadian rhythm;GO:0043278//response to morphine;GO:0043524//negative regulation of neuron apoptotic process;GO:0046777//protein autophosphorylation;GO:0048265//response to pain;GO:0048511//rhythmic process;GO:0050764//regulation of phagocytosis;GO:0060291//long-term synaptic potentiation;GO:0060384//innervation;GO:0099171//presynaptic modulation of chemical synaptic transmission;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:1990911//response to psychosocial stress;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000126602	36.742	34.553	37.269	39.547	42.737	37.209	1280.89	1393.9	1116.93	1218.96	1352.94	1012.85	TRAP1	TNF receptor associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16264]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K09488;K09488	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0009386//translational attenuation;GO:0061077//chaperone-mediated protein folding;GO:1901856//negative regulation of cellular respiration;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903751//negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	--
ENSG00000126603	22.61	26.125	23.6	19.943	22.036	21.016	1829	2125	1410	1195	1506	1237	GLIS2	GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0097730//non-motile cilium	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0030154//cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060994//regulation of transcription from RNA polymerase II promoter involved in kidney development;GO:0061005//cell differentiation involved in kidney development;GO:0061484//hematopoietic stem cell homeostasis;GO:1900182//positive regulation of protein localization to nucleus"	zf-C2H2
ENSG00000126653	2.666	3.555	3.048	1.83	1.389	1.85	120	138	88	43	61	56	NSRP1	nuclear speckle splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25305]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032502//developmental process"	--
ENSG00000126698	47.035	46.278	44.246	34.666	36.09	36.532	1720	1701	1195	939	1115	972	DNAJC8	DnaJ heat shock protein family (Hsp40) member C8 [Source:HGNC Symbol;Acc:HGNC:15470]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0005515//protein binding;GO:0030544//Hsp70 protein binding	-	--
ENSG00000126705	10.875	10.059	11.521	9.309	10.513	10.742	1389	1284	1090	881	1126	999	AHDC1	AT-hook DNA binding motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25230]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000126709	38.155	45.055	43.545	30.147	27.85	37.469	645	765	543	377	397	460	IFI6	interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0001836//release of cytochrome c from mitochondria;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0051902//negative regulation of mitochondrial depolarization;GO:0072593//reactive oxygen species metabolic process;GO:0097190//apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000126733	0.446	0.26	0.347	0.339	0.176	0.419	29	23	20	14	13	20	DACH2	dachshund family transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:16814]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0046545//development of primary female sexual characteristics	DACH
ENSG00000126746	19.877	20.698	21.175	20.662	22.126	22.889	831	832	657	687	766	699	ZNF384	zinc finger protein 384 [Source:HGNC Symbol;Acc:HGNC:11955]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K23480	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000126749	9.431	8.898	8.897	12.803	10.191	9.328	363.13	448.5	299.41	385.51	338.07	309.03	EMG1	EMG1 N1-specific pseudouridine methyltransferase [Source:HGNC Symbol;Acc:HGNC:16912]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14568	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0019843//rRNA binding;GO:0042802//identical protein binding;GO:0070037//rRNA (pseudouridine) methyltransferase activity	GO:0001824//blastocyst development;GO:0006364//rRNA processing;GO:0017126//nucleologenesis;GO:0032259//methylation;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis;GO:0070475//rRNA base methylation	--
ENSG00000126752	0	0.039	0.107	0.905	0.933	0.217	0	1	2	17	20	4	SSX1	SSX family member 1 [Source:HGNC Symbol;Acc:HGNC:11335]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000126756	27.161	25.556	23.715	25.755	22.611	23.42	329	311	214	230	233	214	UXT	ubiquitously expressed prefoldin like chaperone [Source:HGNC Symbol;Acc:HGNC:12641]	-	-	-	-	GO:0000785//chromatin;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0048487//beta-tubulin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000226//microtubule cytoskeleton organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007098//centrosome cycle;GO:0047497//mitochondrion transport along microtubule;GO:0050821//protein stabilization	--
ENSG00000126759	0.056	0	0	0	0.033	0	2	0	0	0	1	0	CFP	complement factor properdin [Source:HGNC Symbol;Acc:HGNC:8864]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K15412	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1904724//tertiary granule lumen	GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response;GO:1903028//positive regulation of opsonization"	--
ENSG00000126767	10.983	11.78	11.003	11.634	12.237	10.817	553	569	445	422	545	417	ELK1	ETS transcription factor ELK1 [Source:HGNC Symbol;Acc:HGNC:3321]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Cancer: specific types;Infectious disease: viral;Endocrine system;Infectious disease: parasitic;Endocrine system;Endocrine system;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04921//Oxytocin signaling pathway;ko05140//Leishmaniasis;ko04910//Insulin signaling pathway;ko04912//GnRH signaling pathway;ko04012//ErbB signaling pathway;ko05213//Endometrial cancer	K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375;K04375	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043679//axon terminus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001889//liver development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009416//response to light stimulus;GO:0010467//gene expression;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071394//cellular response to testosterone stimulus;GO:0071396//cellular response to lipid;GO:0071480//cellular response to gamma radiation;GO:0071774//response to fibroblast growth factor;GO:1901216//positive regulation of neuron death"	ETS
ENSG00000126768	22.262	26.592	23.683	33.576	31.148	32.768	383	461	304	432	453	419	TIMM17B	translocase of inner mitochondrial membrane 17B [Source:HGNC Symbol;Acc:HGNC:17310]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000126773	24.526	23.731	23.496	18.637	19.306	20.54	1539.31	1458.26	1066.18	855.06	1065.16	950.22	PCNX4	pecanex 4 [Source:HGNC Symbol;Acc:HGNC:20349]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000126775	5.951	6.266	4.583	4.514	4.345	4.75	582	616	331	327	359	338	ATG14	autophagy related 14 [Source:HGNC Symbol;Acc:HGNC:19962]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia	K17889;K17889;K17889;K17889;K17889;K17889;K17889;K17889	"GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005930//axoneme;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0034045//phagophore assembly site membrane;GO:0035032//phosphatidylinositol 3-kinase complex, class III;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0045335//phagocytic vesicle;GO:0097629//extrinsic component of omegasome membrane;GO:0097632//extrinsic component of phagophore assembly site membrane"	GO:0005515//protein binding;GO:0051020//GTPase binding	GO:0000045//autophagosome assembly;GO:0000423//mitophagy;GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006622//protein targeting to lysosome;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0009267//cellular response to starvation;GO:0010608//posttranscriptional regulation of gene expression;GO:0016236//macroautophagy;GO:0016240//autophagosome membrane docking;GO:0016241//regulation of macroautophagy;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0042149//cellular response to glucose starvation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045022//early endosome to late endosome transport;GO:0061635//regulation of protein complex stability;GO:0090207//regulation of triglyceride metabolic process;GO:0097352//autophagosome maturation;GO:0098780//response to mitochondrial depolarisation	--
ENSG00000126777	26.479	21.296	15.77	10.933	13.991	16.218	2417	1780	990	649	1014	1000	KTN1	kinectin 1 [Source:HGNC Symbol;Acc:HGNC:6467]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0045296//cadherin binding	GO:0007018//microtubule-based movement;GO:0015031//protein transport	--
ENSG00000126778	0	0.024	0	0	0.029	0	0	1	0	0	1	0	SIX1	SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15614	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001759//organ induction;GO:0001822//kidney development;GO:0003151//outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway;GO:0007389//pattern specification process;GO:0007519//skeletal muscle tissue development;GO:0007605//sensory perception of sound;GO:0008582//regulation of synaptic assembly at neuromuscular junction;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0014033//neural crest cell differentiation;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0014857//regulation of skeletal muscle cell proliferation;GO:0021610//facial nerve morphogenesis;GO:0022008//neurogenesis;GO:0030855//epithelial cell differentiation;GO:0030878//thyroid gland development;GO:0030910//olfactory placode formation;GO:0032880//regulation of protein localization;GO:0034504//protein localization to nucleus;GO:0035909//aorta morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043586//tongue development;GO:0045664//regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048538//thymus development;GO:0048665//neuron fate specification;GO:0048699//generation of neurons;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0048839//inner ear development;GO:0048856//anatomical structure development;GO:0050678//regulation of epithelial cell proliferation;GO:0051451//myoblast migration;GO:0060037//pharyngeal system development;GO:0061055//myotome development;GO:0061197//fungiform papilla morphogenesis;GO:0061551//trigeminal ganglion development;GO:0071599//otic vesicle development;GO:0072075//metanephric mesenchyme development;GO:0072095//regulation of branch elongation involved in ureteric bud branching;GO:0072107//positive regulation of ureteric bud formation;GO:0072172//mesonephric tubule formation;GO:0072193//ureter smooth muscle cell differentiation;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0086100//endothelin receptor signaling pathway;GO:0090103//cochlea morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090336//positive regulation of brown fat cell differentiation;GO:1905243//cellular response to 3,3',5-triiodo-L-thyronine;GO:2000729//positive regulation of mesenchymal cell proliferation involved in ureter development;GO:2001014//regulation of skeletal muscle cell differentiation"	Homeobox
ENSG00000126785	9.976	7.031	8.204	8.867	9.223	9.442	567	489	427	333	445	432	RHOJ	ras homolog family member J [Source:HGNC Symbol;Acc:HGNC:688]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K07864	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0001525//angiogenesis;GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0010594//regulation of endothelial cell migration;GO:0016477//cell migration;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0032488//Cdc42 protein signal transduction;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1903670//regulation of sprouting angiogenesis	--
ENSG00000126787	0.466	0.4	0.453	0.339	0.394	0.232	28	24	20	15	20	9	DLGAP5	DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031616//spindle pole centrosome;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0007346//regulation of mitotic cell cycle;GO:0023052//signaling;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051382//kinetochore assembly;GO:0051642//centrosome localization	--
ENSG00000126790	2.745	3.77	1.994	2.418	2.053	2.956	74	92	42	47	51	55	L3HYPDH	trans-L-3-hydroxyproline dehydratase [Source:HGNC Symbol;Acc:HGNC:20488]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K18384;K18384	-	GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0050346//trans-L-3-hydroxyproline dehydratase activity	-	--
ENSG00000126803	0.927	0.845	1.176	0.808	1.006	0.743	48	44	45	31	44	28	HSPA2	heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0000795//synaptonemal complex;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0036128//CatSper complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0072687//meiotic spindle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0044183//protein folding chaperone;GO:0048156//tau protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding;GO:0051861//glycolipid binding;GO:0097718//disordered domain specific binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006986//response to unfolded protein;GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009408//response to heat;GO:0009409//response to cold;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0032781//positive regulation of ATPase activity;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0070194//synaptonemal complex disassembly;GO:0090084//negative regulation of inclusion body assembly;GO:1901896//positive regulation of ATPase-coupled calcium transmembrane transporter activity	--
ENSG00000126804	11.677	8.438	9.685	7.744	7.194	8.718	758.34	546.44	394.08	355	412.59	418	ZBTB1	zinc finger and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20259]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0016604//nuclear body;GO:0031965//nuclear membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0002711//positive regulation of T cell mediated immunity;GO:0006281//DNA repair;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0019985//translesion synthesis;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0034644//cellular response to UV;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045087//innate immune response;GO:0045582//positive regulation of T cell differentiation;GO:0048538//thymus development;GO:0051260//protein homooligomerization;GO:2000176//positive regulation of pro-T cell differentiation	ZBTB
ENSG00000126814	5.234	4.472	4.918	3.383	3.918	4.402	490	377	271	214	286	259	TRMT5	tRNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:23141]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0016740//transferase activity;GO:0052906//tRNA (guanine(37)-N(1))-methyltransferase activity	GO:0002939//tRNA N1-guanine methylation;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0070901//mitochondrial tRNA methylation	--
ENSG00000126821	7.934	6.571	8.61	7.453	6.996	9.037	549	457	440	382	409	455	SGPP1	sphingosine-1-phosphate phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:17720]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04716;K04716;K04716	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0070780//dihydrosphingosine-1-phosphate phosphatase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006668//sphinganine-1-phosphate metabolic process;GO:0006670//sphingosine metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0035621//ER to Golgi ceramide transport;GO:0045616//regulation of keratinocyte differentiation;GO:0045682//regulation of epidermis development;GO:0046839//phospholipid dephosphorylation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000126822	24.203	25.425	28.128	21.972	25.745	22.285	2165.97	2182	1763.36	1621	1845.35	1751	PLEKHG3	pleckstrin homology and RhoGEF domain containing G3 [Source:HGNC Symbol;Acc:HGNC:20364]	-	-	-	-	GO:0005829//cytosol	GO:0003779//actin binding;GO:0005085//guanyl-nucleotide exchange factor activity	GO:0030334//regulation of cell migration;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000126838	0	0	0	0	0	0	0	0	0	0	0	0	PZP	PZP alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0007565//female pregnancy;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000126856	0	0	0	0.019	0	0.059	0	0	0	1	0	3	PRDM7	PR/SET domain 7 [Source:HGNC Symbol;Acc:HGNC:9351]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K20796;K20796	GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0010844//recombination hotspot binding;GO:0016740//transferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0010452//histone H3-K36 methylation;GO:0010468//regulation of gene expression;GO:0010845//positive regulation of reciprocal meiotic recombination;GO:0016571//histone methylation;GO:0032259//methylation;GO:0080182//histone H3-K4 trimethylation"	--
ENSG00000126858	15.46	14.013	13.561	12.54	14.368	15.152	1004	877	642	575	730	692	RHOT1	ras homolog family member T1 [Source:HGNC Symbol;Acc:HGNC:21168]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K07870	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0007005//mitochondrion organization;GO:0007264//small GTPase mediated signal transduction;GO:0010821//regulation of mitochondrion organization;GO:0019725//cellular homeostasis;GO:0047497//mitochondrion transport along microtubule;GO:0097345//mitochondrial outer membrane permeabilization	--
ENSG00000126860	0	0	0	0	0.037	0	0	0	0	0	1	0	EVI2A	ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	-	--
ENSG00000126861	3.178	3.162	1.802	1.98	1.35	1.643	117	117	49	54	42	44	OMG	oligodendrocyte myelin glycoprotein [Source:HGNC Symbol;Acc:HGNC:8135]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0031102//neuron projection regeneration	--
ENSG00000126870	3.69	3.291	3.042	2.267	2.705	2.763	290	260	162	132	173	158	DYNC2I1	dynein 2 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:21862]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000922//spindle pole;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005929//cilium;GO:0031021//interphase microtubule organizing center;GO:0042995//cell projection;GO:0097014//ciliary plasm;GO:0097542//ciliary tip;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0007018//microtubule-based movement;GO:0030030//cell projection organization;GO:0035721//intraciliary retrograde transport;GO:0042073//intraciliary transport;GO:0048704//embryonic skeletal system morphogenesis;GO:0060271//cilium assembly	--
ENSG00000126878	6.18	6.234	7.73	10.908	9.215	8.144	353	422	294	454	426	350	AIF1L	allograft inflammatory factor 1 like [Source:HGNC Symbol;Acc:HGNC:28904]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0051017//actin filament bundle assembly;GO:0097178//ruffle assembly	--
ENSG00000126882	0.455	0.576	0.15	0.497	0.392	0.651	27	23	9	23	27	31	FAM78A	family with sequence similarity 78 member A [Source:HGNC Symbol;Acc:HGNC:25465]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000126883	11.352	11.723	16.236	14.46	15.566	15.182	1597	1646	1377	1411	1673	1277	NUP214	nucleoporin 214 [Source:HGNC Symbol;Acc:HGNC:8064]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14317;K14317	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:1990876//cytoplasmic side of nuclear pore	GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0000278//mitotic cell cycle;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0046822//regulation of nucleocytoplasmic transport;GO:0051028//mRNA transport;GO:0051726//regulation of cell cycle	--
ENSG00000126890	0	0	0	0	0	0	0	0	0	0	0	0	CTAG2	cancer/testis antigen 2 [Source:HGNC Symbol;Acc:HGNC:2492]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0070525//tRNA threonylcarbamoyladenosine metabolic process	--
ENSG00000126895	0.03	0	0	0	0	0	1	0	0	0	0	0	AVPR2	arginine vasopressin receptor 2 [Source:HGNC Symbol;Acc:HGNC:897]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Excretory system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04962//Vasopressin-regulated water reabsorption	K04228;K04228;K04228	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004930//G protein-coupled receptor activity;GO:0005000//vasopressin receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding	GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0003092//renal water retention;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007599//hemostasis;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0021537//telencephalon development;GO:0034097//response to cytokine;GO:0035811//negative regulation of urine volume;GO:0035814//negative regulation of renal sodium excretion;GO:0045777//positive regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction	--
ENSG00000126903	8.717	9.718	10.169	9.576	9.587	9.134	387	424	324	295	355	268	SLC10A3	solute carrier family 10 member 3 [Source:HGNC Symbol;Acc:HGNC:22979]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008508//bile acid:sodium symporter activity;GO:0015293//symporter activity	GO:0010033//response to organic substance;GO:0015721//bile acid and bile salt transport;GO:0032526//response to retinoic acid;GO:0055085//transmembrane transport	--
ENSG00000126934	76.491	74.711	78.166	91.941	81.913	75.967	2740	2690	2068	2349	2479	1980	MAP2K2	mitogen-activated protein kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6842]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Signal transduction;Immune system;Immune system;Cancer: overview;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04660//T cell receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030165//PDZ domain binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0036289//peptidyl-serine autophosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070371//ERK1 and ERK2 cascade;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090170//regulation of Golgi inheritance;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:2000641//regulation of early endosome to late endosome transport"	--
ENSG00000126945	52.145	53.261	55.855	51.18	49.315	56.739	2483.31	2549.52	1964.6	1805.45	1984.2	1966.08	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 [Source:HGNC Symbol;Acc:HGNC:5042]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0043484//regulation of RNA splicing	--
ENSG00000126947	16.267	14.152	17.725	14.487	15.924	16.339	717	627	577	473	593	524	ARMCX1	armadillo repeat containing X-linked 1 [Source:HGNC Symbol;Acc:HGNC:18073]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000126950	0.331	0.518	0.384	0.638	0.392	0.325	14	22	12	20	14	10	TMEM35A	transmembrane protein 35A [Source:HGNC Symbol;Acc:HGNC:25864]	-	-	-	-	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0030548//acetylcholine receptor regulator activity	GO:0051131//chaperone-mediated protein complex assembly;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000126953	3.269	2.651	3.065	3.608	2.738	1.999	90	77	64	76	70	50	TIMM8A	translocase of inner mitochondrial membrane 8A [Source:HGNC Symbol;Acc:HGNC:11817]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006626//protein targeting to mitochondrion;GO:0007399//nervous system development;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000126970	6.981	6.528	6.044	5.381	5.072	6.906	356	332	223	203	219	252	ZC4H2	zinc finger C4H2-type containing [Source:HGNC Symbol;Acc:HGNC:24931]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0003358//noradrenergic neuron development;GO:0006513//protein monoubiquitination;GO:0007399//nervous system development;GO:0007528//neuromuscular junction development;GO:0021522//spinal cord motor neuron differentiation;GO:0030154//cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:2000677//regulation of transcription regulatory region DNA binding	--
ENSG00000127022	337.96	323.588	306.664	313.198	318.557	313.734	24002	22985	16189	16617.8	19273.96	16026	CANX	calnexin [Source:HGNC Symbol;Acc:HGNC:1473]	Human Diseases;Cellular Processes;Genetic Information Processing;Organismal Systems;Organismal Systems	"Infectious disease: viral;Transport and catabolism;Folding, sorting and degradation;Immune system;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko04141//Protein processing in endoplasmic reticulum;ko04612//Antigen processing and presentation;ko04918//Thyroid hormone synthesis	K08054;K08054;K08054;K08054;K08054	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005840//ribosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0032839//dendrite cytoplasm;GO:0032991//protein-containing complex;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0034185//apolipoprotein binding;GO:0035255//ionotropic glutamate receptor binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007568//aging;GO:0009306//protein secretion;GO:0019082//viral protein processing;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034975//protein folding in endoplasmic reticulum;GO:0048488//synaptic vesicle endocytosis;GO:0072583//clathrin-dependent endocytosis	--
ENSG00000127054	23.118	24.243	27.333	28.707	27.848	26.748	950	1034	849	855	930	798	INTS11	integrator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:26052]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032039//integrator complex;GO:0072562//blood microparticle	GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0016180//snRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000127074	0	0	0	0	0	0	0	0	0	0	0	0	RGS13	regulator of G protein signaling 13 [Source:HGNC Symbol;Acc:HGNC:9995]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003924//GTPase activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway	--
ENSG00000127080	3.593	3.528	6.161	4.563	3.897	4.32	232.2	231.61	205.38	173.48	194.64	195.27	IPPK	inositol-pentakisphosphate 2-kinase [Source:HGNC Symbol;Acc:HGNC:14645]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K10572;K10572;K10572	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035299//inositol pentakisphosphate 2-kinase activity;GO:0060090//molecular adaptor activity	GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0052746//inositol phosphorylation;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	--
ENSG00000127081	2.125	1.844	1.469	1.415	1.634	1.557	172	143	74	80	108	82	ZNF484	zinc finger protein 484 [Source:HGNC Symbol;Acc:HGNC:23385]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000127083	0	0	0	0	0.013	0	0	0	0	0	1	0	OMD	osteomodulin [Source:HGNC Symbol;Acc:HGNC:8134]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0030500//regulation of bone mineralization	--
ENSG00000127084	0.459	0.51	0.47	0.896	0.768	0.739	30	35	22	43	44	35	FGD3	"FYVE, RhoGEF and PH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16027]"	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05722	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000127124	0.222	0.205	0.283	0.196	0.163	0.336	58	54	53	38	35	63	HIVEP3	HIVEP zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:13561]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0035914//skeletal muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000127125	26.781	26.881	28.906	28.571	27.193	29.896	595	599	466	459	514	498	PPCS	phosphopantothenoylcysteine synthetase [Source:HGNC Symbol;Acc:HGNC:25686]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K01922;K01922	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004632//phosphopantothenate--cysteine ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0003015//heart process;GO:0006085//acetyl-CoA biosynthetic process;GO:0015937//coenzyme A biosynthetic process	--
ENSG00000127129	4.04	3.79	3.699	4.311	4.418	3.173	105	99	71	83	97	60	EDN2	endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Circulatory system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04270//Vascular smooth muscle contraction;ko04924//Renin secretion	K16367;K16367;K16367;K16367	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0031708//endothelin B receptor binding	GO:0001516//prostaglandin biosynthetic process;GO:0001525//angiogenesis;GO:0001659//temperature homeostasis;GO:0001944//vasculature development;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0003058//hormonal regulation of the force of heart contraction;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0006874//cellular calcium ion homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell population proliferation;GO:0009932//cell tip growth;GO:0010460//positive regulation of heart rate;GO:0014824//artery smooth muscle contraction;GO:0014826//vein smooth muscle contraction;GO:0019221//cytokine-mediated signaling pathway;GO:0019229//regulation of vasoconstriction;GO:0019722//calcium-mediated signaling;GO:0030593//neutrophil chemotaxis;GO:0031175//neuron projection development;GO:0042116//macrophage activation;GO:0042310//vasoconstriction;GO:0043542//endothelial cell migration;GO:0045987//positive regulation of smooth muscle contraction;GO:0048016//inositol phosphate-mediated signaling;GO:0048246//macrophage chemotaxis;GO:0048286//lung alveolus development;GO:0048675//axon extension;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0097009//energy homeostasis	--
ENSG00000127152	0.629	0.499	0.412	0.252	0.279	0.279	103	80	48	33	40	32	BCL11B	BAF chromatin remodeling complex subunit BCL11B [Source:HGNC Symbol;Acc:HGNC:13222]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K22046	GO:0005634//nucleus;GO:0016514//SWI/SNF complex;GO:0043005//neuron projection	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0003334//keratinocyte development;GO:0003382//epithelial cell morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0010837//regulation of keratinocyte proliferation;GO:0019216//regulation of lipid metabolic process;GO:0021773//striatal medium spiny neuron differentiation;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0021953//central nervous system neuron differentiation;GO:0031077//post-embryonic camera-type eye development;GO:0033077//T cell differentiation in thymus;GO:0033153//T cell receptor V(D)J recombination;GO:0035701//hematopoietic stem cell migration;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043368//positive T cell selection;GO:0043588//skin development;GO:0045664//regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046632//alpha-beta T cell differentiation;GO:0048538//thymus development;GO:0071678//olfactory bulb axon guidance;GO:0097535//lymphoid lineage cell migration into thymus	zf-C2H2
ENSG00000127184	160.184	166.348	184.723	208.516	153.921	187.742	2092	2186	1785	2019	1699	1786	COX7C	cytochrome c oxidase subunit 7C [Source:HGNC Symbol;Acc:HGNC:2292]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272;K02272	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration"	--
ENSG00000127191	4.079	3.914	5.023	4.222	3.3	4.548	187	169	161	147	126	147	TRAF2	TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	"Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Folding, sorting and degradation;Endocrine and metabolic disease;Cell growth and death;Infectious disease: viral;Neurodegenerative disease;Cell growth and death;Development and regeneration;Signal transduction;Signal transduction;Immune system;Cancer: specific types;Immune system;Endocrine system"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05160//Hepatitis C;ko05017//Spinocerebellar ataxia;ko04210//Apoptosis;ko04380//Osteoclast differentiation;ko04071//Sphingolipid signaling pathway;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko04622//RIG-I-like receptor signaling pathway;ko04920//Adipocytokine signaling pathway	K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173;K03173	GO:0000151//ubiquitin ligase complex;GO:0002947//tumor necrosis factor receptor superfamily complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0009898//cytoplasmic side of plasma membrane;GO:0012506//vesicle membrane;GO:0032991//protein-containing complex;GO:0035631//CD40 receptor complex;GO:0045121//membrane raft;GO:0097057//TRAF2-GSTP1 complex;GO:1990604//IRE1-TRAF2-ASK1 complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005174//CD40 receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0042802//identical protein binding;GO:0043120//tumor necrosis factor binding;GO:0044877//protein-containing complex binding;GO:0046625//sphingolipid binding;GO:0046872//metal ion binding	GO:0002637//regulation of immunoglobulin production;GO:0002726//positive regulation of T cell cytokine production;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0016567//protein ubiquitination;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030163//protein catabolic process;GO:0032743//positive regulation of interleukin-2 production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034351//negative regulation of glial cell apoptotic process;GO:0034622//cellular protein-containing complex assembly;GO:0034976//response to endoplasmic reticulum stress;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0043507//positive regulation of JUN kinase activity;GO:0046328//regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0048255//mRNA stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:0065003//protein-containing complex assembly;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070534//protein K63-linked ubiquitination;GO:0071732//cellular response to nitric oxide;GO:0097300//programmed necrotic cell death;GO:0097400//interleukin-17-mediated signaling pathway;GO:1901215//negative regulation of neuron death;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000127220	16.123	17.347	18.026	20.463	17.908	20.896	682.89	738.5	563.88	642	625.74	636	ABHD8	abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759]	-	-	-	-	GO:0005739//mitochondrion;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006654//phosphatidic acid biosynthetic process;GO:0055088//lipid homeostasis	--
ENSG00000127241	2.17	2.704	1.545	0.828	0.951	0.815	154	207	82	36	51	37	MASP1	MBL associated serine protease 1 [Source:HGNC Symbol;Acc:HGNC:6901]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K03992;K03992;K03992	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0045916//negative regulation of complement activation"	--
ENSG00000127249	3.882	3.694	3.757	2.438	2.825	2.031	294	364	254	121	178	145	ATP13A4	ATPase 13A4 [Source:HGNC Symbol;Acc:HGNC:25422]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000127252	4.111	4.238	4.387	4.548	3.434	2.414	86	89	66	60	61	36	PLAAT1	phospholipase A and acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:14922]	-	-	-	-	GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0008970//phospholipase A1 activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process;GO:0070306//lens fiber cell differentiation;GO:1903008//organelle disassembly	--
ENSG00000127311	0.417	0.098	0.188	0.337	0.244	0.229	30	7	10	18	14	12	HELB	DNA helicase B [Source:HGNC Symbol;Acc:HGNC:17196]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0035861//site of double-strand break	GO:0000166//nucleotide binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0043139//5'-3' DNA helicase activity;GO:0044877//protein-containing complex binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:1903775//regulation of DNA double-strand break processing;GO:2000042//negative regulation of double-strand break repair via homologous recombination"	--
ENSG00000127314	62.609	53.228	54.082	53.067	50.076	53.717	2157	1872	1434	1319	1504	1335	RAP1B	"RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cardiovascular disease;Cellular community - eukaryotes;Immune system;Endocrine and metabolic disease;Immune system;Nervous system;Immune system;Digestive system;Cancer: specific types;Nervous system	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04934//Cushing syndrome;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04972//Pancreatic secretion;ko05211//Renal cell carcinoma;ko04720//Long-term potentiation	K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836;K07836	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0035577//azurophil granule membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0044877//protein-containing complex binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008283//cell population proliferation;GO:0032486//Rap protein signal transduction;GO:0033625//positive regulation of integrin activation;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0061028//establishment of endothelial barrier;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:1901888//regulation of cell junction assembly;GO:2000114//regulation of establishment of cell polarity;GO:2000301//negative regulation of synaptic vesicle exocytosis	--
ENSG00000127318	0	0.238	0	0	0	0	0	3	0	0	0	0	IL22	interleukin 22 [Source:HGNC Symbol;Acc:HGNC:14900]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Signal transduction;Immune system;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease	K05445;K05445;K05445;K05445	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0045518//interleukin-22 receptor binding	GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0051384//response to glucocorticoid	--
ENSG00000127324	4.732	4.086	5.021	4.252	3.28	4.769	111	97	87	75	66	82	TSPAN8	tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0010468//regulation of gene expression;GO:0030195//negative regulation of blood coagulation	--
ENSG00000127325	0.218	0.25	0.089	0.226	0.099	0.118	13	15	4	10	5	6	BEST3	bestrophin 3 [Source:HGNC Symbol;Acc:HGNC:17105]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0003674//molecular_function;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0008150//biological_process;GO:0015698//inorganic anion transport;GO:0043271//negative regulation of ion transport	--
ENSG00000127328	28.153	24.969	38.317	26.56	19.762	29.98	1331	1065	883	754	859	895	RAB3IP	RAB3A interacting protein [Source:HGNC Symbol;Acc:HGNC:16508]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0070319//Golgi to plasma membrane transport vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006612//protein targeting to membrane;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0033365//protein localization to organelle;GO:0050790//regulation of catalytic activity;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking	--
ENSG00000127329	1.894	1.667	1.485	0.958	1.388	0.97	277	266	131	107	158	96	PTPRB	protein tyrosine phosphatase receptor type B [Source:HGNC Symbol;Acc:HGNC:9665]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K05694	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043235//receptor complex;GO:0070821//tertiary granule membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030246//carbohydrate binding;GO:0045296//cadherin binding	GO:0001525//angiogenesis;GO:0006470//protein dephosphorylation;GO:0006796//phosphate-containing compound metabolic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000127334	6.343	5.331	5.108	4.243	5.227	5.552	820	682	511	423	581	499	DYRK2	dual specificity tyrosine phosphorylation regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:3093]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030145//manganese ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007224//smoothened signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000127337	11.33	10.453	10.377	9.064	8.797	9.285	335	297	223	194	213	191	YEATS4	YEATS domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24859]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0031965//nuclear membrane;GO:0035267//NuA4 histone acetyltransferase complex	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042393//histone binding;GO:0070577//lysine-acetylated histone binding;GO:0140030//modification-dependent protein binding	"GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	Others
ENSG00000127362	0.044	0.044	0	0	0	0	1	1	0	0	0	0	TAS2R3	taste 2 receptor member 3 [Source:HGNC Symbol;Acc:HGNC:14910]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000127364	0.231	0.115	0.208	0.065	0.125	0.198	24	12	16	5	11	15	TAS2R4	taste 2 receptor member 4 [Source:HGNC Symbol;Acc:HGNC:14911]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000127366	0.126	0.167	0.17	0.17	0.149	0.058	3	4	3	3	3	1	TAS2R5	taste 2 receptor member 5 [Source:HGNC Symbol;Acc:HGNC:14912]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007635//chemosensory behavior;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000127377	0.258	0.069	0.131	0.131	0.029	0.1	9	1	4	4	1	3	CRYGN	crystallin gamma N [Source:HGNC Symbol;Acc:HGNC:20458]	-	-	-	-	-	GO:0005212//structural constituent of eye lens	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000127399	4.877	5.186	6.141	5.886	5.831	6.389	182	191	169	160	183	175	LRRC61	leucine rich repeat containing 61 [Source:HGNC Symbol;Acc:HGNC:21704]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000127412	0	0	0	0	0	0	0	0	0	0	0	0	TRPV5	transient receptor potential cation channel subfamily V member 5 [Source:HGNC Symbol;Acc:HGNC:3145]	Organismal Systems;Organismal Systems	Endocrine system;Excretory system	"ko04928//Parathyroid hormone synthesis, secretion and action;ko04961//Endocrine and other factor-regulated calcium reabsorption"	K04974;K04974	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031224//intrinsic component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0034704//calcium channel complex	GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0035809//regulation of urine volume;GO:0051289//protein homotetramerization;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0060402//calcium ion transport into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0098703//calcium ion import across plasma membrane	--
ENSG00000127415	9.224	10.269	9.273	11.839	10.745	9.515	418	468	310	397	411	309	IDUA	alpha-L-iduronidase [Source:HGNC Symbol;Acc:HGNC:5391]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01217;K01217;K01217	GO:0005764//lysosome;GO:0030135//coated vesicle;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0003940//L-iduronidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005102//signaling receptor binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0005984//disaccharide metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008152//metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0030209//dermatan sulfate catabolic process;GO:0030211//heparin catabolic process	--
ENSG00000127418	45.7	48.888	48.043	47.091	51.069	48.769	3053	3370	2368	2362	2884	2422	FGFRL1	fibroblast growth factor receptor like 1 [Source:HGNC Symbol;Acc:HGNC:3693]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0044291//cell-cell contact zone	GO:0005007//fibroblast growth factor-activated receptor activity;GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding	GO:0001501//skeletal system development;GO:0003179//heart valve morphogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060412//ventricular septum morphogenesis;GO:0060539//diaphragm development;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000127419	17.328	20.595	17.561	17.52	21.376	16.947	469	499	374	401	453	337	TMEM175	transmembrane protein 175 [Source:HGNC Symbol;Acc:HGNC:28709]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031303//integral component of endosome membrane;GO:1905103//integral component of lysosomal membrane	GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0035751//regulation of lysosomal lumen pH;GO:0070050//neuron cellular homeostasis;GO:0071805//potassium ion transmembrane transport;GO:0090385//phagosome-lysosome fusion	--
ENSG00000127423	0.26	0.477	0.272	0.211	0.399	0.391	11	17.03	9	7	14.01	9	AUNIP	aurora kinase A and ninein interacting protein [Source:HGNC Symbol;Acc:HGNC:28363]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0090734//site of DNA damage	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007051//spindle organization;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000127445	37.174	38.107	44.129	50.194	42.754	45.826	778	793	672	770	740	697	PIN1	"peptidylprolyl cis/trans isomerase, NIMA-interacting 1 [Source:HGNC Symbol;Acc:HGNC:8988]"	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K09578	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030496//midbody;GO:0036064//ciliary basal body;GO:0098978//glutamatergic synapse;GO:0099524//postsynaptic cytosol	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0003774//cytoskeletal motor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016853//isomerase activity;GO:0016859//cis-trans isomerase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0032794//GTPase activating protein binding;GO:0048156//tau protein binding;GO:0050815//phosphoserine residue binding;GO:0050816//phosphothreonine residue binding;GO:0051219//phosphoprotein binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0001666//response to hypoxia;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0010468//regulation of gene expression;GO:0030182//neuron differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032465//regulation of cytokinesis;GO:0035307//positive regulation of protein dephosphorylation;GO:0042177//negative regulation of protein catabolic process;GO:0043547//positive regulation of GTPase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050808//synapse organization;GO:0050821//protein stabilization;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1900180//regulation of protein localization to nucleus;GO:1902430//negative regulation of amyloid-beta formation;GO:2000146//negative regulation of cell motility	--
ENSG00000127452	4.97	5.932	6.756	5.881	5.25	6.254	166	194	155	127	133	153	FBXL12	F-box and leucine rich repeat protein 12 [Source:HGNC Symbol;Acc:HGNC:13611]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0051726//regulation of cell cycle	--
ENSG00000127463	18.502	17.184	16.306	16.934	18.407	19.308	1319	1453	981	968	1279	1043	EMC1	ER membrane protein complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28957]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032991//protein-containing complex;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000127472	8.345	9.153	13.886	12.149	12.198	10.951	332	366	408	358	410	317	PLA2G5	phospholipase A2 group V [Source:HGNC Symbol;Acc:HGNC:9038]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0032009//early phagosome;GO:0032010//phagolysosome;GO:0045335//phagocytic vesicle;GO:0055037//recycling endosome	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0047499//calcium-independent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006909//phagocytosis;GO:0009395//phospholipid catabolic process;GO:0010518//positive regulation of phospholipase activity;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016042//lipid catabolic process;GO:0019370//leukotriene biosynthetic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0034638//phosphatidylcholine catabolic process;GO:0035965//cardiolipin acyl-chain remodeling;GO:0050482//arachidonic acid secretion;GO:0050766//positive regulation of phagocytosis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090265//positive regulation of immune complex clearance by monocytes and macrophages;GO:0090385//phagosome-lysosome fusion;GO:1903028//positive regulation of opsonization;GO:1905036//positive regulation of antifungal innate immune response;GO:1905164//positive regulation of phagosome maturation	--
ENSG00000127481	23.725	24.761	26.94	22.874	26.027	25.269	6098	6564	5083	4310	5511	4947	UBR4	ubiquitin protein ligase E3 component n-recognin 4 [Source:HGNC Symbol;Acc:HGNC:30313]	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis	K10691;K10691	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000127483	39.216	42.347	37.674	35.167	37.94	39.046	2192	2112	1438	1364	1630	1411	HP1BP3	heterochromatin protein 1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:24973]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031491//nucleosome binding	"GO:0006334//nucleosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell population proliferation;GO:0070828//heterochromatin organization;GO:0071456//cellular response to hypoxia;GO:0097298//regulation of nucleus size"	--
ENSG00000127507	0	0	0	0	0	0	0	0	0	0	0	0	ADGRE2	adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031256//leading edge membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0035374//chondroitin sulfate binding	GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0016477//cell migration;GO:0043304//regulation of mast cell degranulation;GO:0071621//granulocyte chemotaxis	--
ENSG00000127511	13.373	13.451	13.217	13.933	14.655	13.528	1257	1304	934	985	1170	922	SIN3B	SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0000805//X chromosome;GO:0000806//Y chromosome;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016580//Sin3 complex;GO:0030849//autosome	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0030336//negative regulation of cell migration;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000127515	0	0	0	0	0	0	0	0	0	0	0	0	OR7A10	olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000127526	21.289	20.193	20.335	19.245	17.645	16.524	1978	1903	1460	1458	1585	1227	SLC35E1	solute carrier family 35 member E1 [Source:HGNC Symbol;Acc:HGNC:20803]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0055085//transmembrane transport	--
ENSG00000127527	17.404	15.902	16.737	20.906	18.33	17.776	998	969	746	919	877	767	EPS15L1	epidermal growth factor receptor pathway substrate 15 like 1 [Source:HGNC Symbol;Acc:HGNC:24634]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12472	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030132//clathrin coat of coated pit	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0016197//endosomal transport	--
ENSG00000127528	0.831	0.348	0.324	0.171	0.344	0.376	21	20	14	6	17	6	KLF2	Kruppel like factor 2 [Source:HGNC Symbol;Acc:HGNC:6347]	Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Cardiovascular disease;Signal transduction	ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04068//FoxO signaling pathway	K17845;K17845;K17845	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032715//negative regulation of interleukin-6 production;GO:0034101//erythrocyte homeostasis;GO:0034616//response to laminar fluid shear stress;GO:0035264//multicellular organism growth;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0040029//regulation of gene expression, epigenetic;GO:0042311//vasodilation;GO:0043249//erythrocyte maturation;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0051247//positive regulation of protein metabolic process;GO:0060509//type I pneumocyte differentiation;GO:0070301//cellular response to hydrogen peroxide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0071409//cellular response to cycloheximide;GO:0071498//cellular response to fluid shear stress;GO:0071499//cellular response to laminar fluid shear stress;GO:0097533//cellular stress response to acid chemical;GO:1901653//cellular response to peptide;GO:1903671//negative regulation of sprouting angiogenesis"	zf-C2H2
ENSG00000127529	0	0	0	0	0	0	0	0	0	0	0	0	OR7C2	olfactory receptor family 7 subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:8374]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000127530	0	0	0	0	0	0	0	0	0	0	0	0	OR7C1	olfactory receptor family 7 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8373]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000127533	0.029	0.014	0	0.059	0	0	2	1	0	3	0	0	F2RL3	F2R like thrombin or trypsin receptor 3 [Source:HGNC Symbol;Acc:HGNC:3540]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Immune system;Immune system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04015//Rap1 signaling pathway;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K04236;K04236;K04236;K04236;K04236	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0015057//thrombin-activated receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009611//response to wounding;GO:0030168//platelet activation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060155//platelet dense granule organization;GO:0070493//thrombin-activated receptor signaling pathway	--
ENSG00000127540	32.521	31.156	39.638	44.876	34.047	37.726	875.09	839.08	787.69	893.53	775.03	739.6	UQCR11	"ubiquinol-cytochrome c reductase, complex III subunit XI [Source:HGNC Symbol;Acc:HGNC:30862]"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0009055//electron transfer activity	"GO:0006091//generation of precursor metabolites and energy;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0045333//cellular respiration"	--
ENSG00000127554	8.898	7.291	9.174	13.207	8.338	8.337	434	359	278	347	344	297	GFER	"growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0016972//thiol oxidase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0001889//liver development;GO:0007165//signal transduction;GO:0032496//response to lipopolysaccharide;GO:0043066//negative regulation of apoptotic process;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0072717//cellular response to actinomycin D;GO:0097237//cellular response to toxic substance;GO:0097421//liver regeneration;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000127561	1.142	0.971	1.103	0.9	1.172	1.414	48	41	34	28	41	43	SYNGR3	synaptogyrin 3 [Source:HGNC Symbol;Acc:HGNC:11501]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0045202//synapse	GO:0005515//protein binding;GO:0042169//SH2 domain binding;GO:0047485//protein N-terminus binding	GO:0001504//neurotransmitter uptake;GO:0021762//substantia nigra development;GO:0032411//positive regulation of transporter activity;GO:0045055//regulated exocytosis	--
ENSG00000127564	0.35	0.18	0.357	0.564	0.572	0.176	11.05	4	12.03	12.02	21.09	5.02	PKMYT1	"protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:HGNC:29650]"	Cellular Processes;Cellular Processes;Organismal Systems	Cell growth and death;Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K06633;K06633;K06633	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0016310//phosphorylation;GO:0051321//meiotic cell cycle	--
ENSG00000127578	0.171	0.17	0.033	0.329	0.116	0.134	7	7	1	10	4	4	WFIKKN1	"WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912]"	-	-	-	-	GO:0005576//extracellular region	GO:0004857//enzyme inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0048019//receptor antagonist activity;GO:0050431//transforming growth factor beta binding	GO:0001501//skeletal system development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0043392//negative regulation of DNA binding;GO:0055001//muscle cell development;GO:0060021//roof of mouth development;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000127580	8.964	10.308	9.581	10.777	10.54	10.584	603	697	476	537	599	518	WDR24	WD repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:20852]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20408	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0061700//GATOR2 complex	GO:0005515//protein binding	GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:1904262//negative regulation of TORC1 signaling;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000127585	0.028	0.097	0.058	0.134	0.231	0.039	2	5	2	7	10	2	FBXL16	F-box and leucine rich repeat protein 16 [Source:HGNC Symbol;Acc:HGNC:14150]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000127586	2.822	3.058	2.51	2.306	3.51	2.623	181	194	115	108	174	121	CHTF18	chromosome transmission fidelity factor 18 [Source:HGNC Symbol;Acc:HGNC:18435]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031390//Ctf18 RFC-like complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity	GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0032508//DNA duplex unwinding;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000127588	0	0	0	0	0	0	0	0	0	0	0	0	GNG13	G protein subunit gamma 13 [Source:HGNC Symbol;Acc:HGNC:14131]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Sensory system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04740//Olfactory transduction;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction	K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547;K04547	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite	GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0050909//sensory perception of taste	--
ENSG00000127603	42.586	35.484	33.064	22.358	25.065	25.01	7854	6381	4385	2637	3687	3051	MACF1	microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008092//cytoskeletal protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0051011//microtubule minus-end binding;GO:0051015//actin filament binding	GO:0010632//regulation of epithelial cell migration;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030334//regulation of cell migration;GO:0032886//regulation of microtubule-based process;GO:0042060//wound healing;GO:0043001//Golgi to plasma membrane protein transport;GO:0045104//intermediate filament cytoskeleton organization;GO:0045773//positive regulation of axon extension;GO:0051893//regulation of focal adhesion assembly;GO:0150011//regulation of neuron projection arborization	--
ENSG00000127616	44.922	45.725	44.765	40.016	42.283	35.359	4318	4517	3341	3002	3565	2552	SMARCA4	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11647;K11647	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0070603//SWI/SNF superfamily-type complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex;GO:0140288//GBAF complex	"GO:0000166//nucleotide binding;GO:0001164//RNA polymerase I core promoter sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030957//Tat protein binding;GO:0031492//nucleosomal DNA binding;GO:0042393//histone binding;GO:0047485//protein N-terminus binding;GO:0050681//androgen receptor binding;GO:0070182//DNA polymerase binding;GO:0070577//lysine-acetylated histone binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0003407//neural retina development;GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0043923//positive regulation by host of viral transcription;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051276//chromosome organization;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0070316//regulation of G0 to G1 transition;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1902459//positive regulation of stem cell population maintenance;GO:1902661//positive regulation of glucose mediated signaling pathway;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000127663	11.103	12.346	11.098	11.609	12.323	10.939	1251	1404	893	958	1133	869	KDM4B	lysine demethylase 4B [Source:HGNC Symbol;Acc:HGNC:29136]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005829//cytosol;GO:0043229//intracellular organelle	GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140684//histone H3-tri/dimethyl-lysine-9 demethylase activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0033169//histone H3-K9 demethylation;GO:0070076//histone lysine demethylation;GO:0070544//histone H3-K36 demethylation;GO:1900113//negative regulation of histone H3-K9 trimethylation	--
ENSG00000127666	2.928	2.663	3.308	3.201	3.551	2.913	163	149	136	132	167	118	TICAM1	toll like receptor adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:18348]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Signal transduction;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Cancer: overview;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis	K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842;K05842	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0097342//ripoptosome	GO:0003953//NAD+ nucleosidase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0030890//positive regulation of B cell proliferation;GO:0031398//positive regulation of protein ubiquitination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0032722//positive regulation of chemokine production;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050871//positive regulation of B cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0071222//cellular response to lipopolysaccharide;GO:0097190//apoptotic signaling pathway;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900017//positive regulation of cytokine production involved in inflammatory response	--
ENSG00000127720	2.047	1.766	2.119	1.577	1.299	1.894	76	76	67	50	47	59	METTL25	methyltransferase like 25 [Source:HGNC Symbol;Acc:HGNC:26228]	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000127743	0	0	0	0	0.24	0	0	0	0	0	3	0	IL17B	interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04657//IL-17 signaling pathway	K05490;K05490	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:1900017//positive regulation of cytokine production involved in inflammatory response	--
ENSG00000127774	27.552	33.768	40.931	39.541	36.514	42.62	382	472.28	417.37	407.04	430.33	431.45	EMC6	ER membrane protein complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:28430]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0072546//EMC complex;GO:0097631//integral component of omegasome membrane	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0000045//autophagosome assembly;GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000127780	0	0	0	0	0	0	0	0	0	0	0	0	OR1E2	olfactory receptor family 1 subfamily E member 2 [Source:HGNC Symbol;Acc:HGNC:8190]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0038023//signaling receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000127804	8.932	8.352	7.494	8.778	10.415	9.757	842	905.06	640	693	843	671	METTL16	"methyltransferase 16, N6-methyladenosine [Source:HGNC Symbol;Acc:HGNC:28484]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0001734//mRNA (N6-adenosine)-methyltransferase activity;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0030629//U6 snRNA 3'-end binding;GO:0035613//RNA stem-loop binding;GO:0052907//23S rRNA (adenine(1618)-N(6))-methyltransferase activity;GO:0120048//U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	"GO:0006402//mRNA catabolic process;GO:0006556//S-adenosylmethionine biosynthetic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0032259//methylation;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0061157//mRNA destabilization;GO:0070475//rRNA base methylation;GO:0080009//mRNA methylation;GO:0120049//snRNA (adenine-N6)-methylation;GO:1905869//negative regulation of 3'-UTR-mediated mRNA stabilization"	--
ENSG00000127824	12.279	12.282	11.514	11.462	11.821	16.545	392.3	366.91	286.19	306.96	361.06	339.66	TUBA4A	tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process	--
ENSG00000127831	0	0	0	0	0	0	0	0	0	0	0	0	VIL1	villin 1 [Source:HGNC Symbol;Acc:HGNC:12690]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0032432//actin filament bundle;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0070062//extracellular exosome	"GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035727//lysophosphatidic acid binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0051015//actin filament binding"	GO:0001951//intestinal D-glucose absorption;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008154//actin polymerization or depolymerization;GO:0008360//regulation of cell shape;GO:0009617//response to bacterium;GO:0010634//positive regulation of epithelial cell migration;GO:0030041//actin filament polymerization;GO:0030042//actin filament depolymerization;GO:0030335//positive regulation of cell migration;GO:0030836//positive regulation of actin filament depolymerization;GO:0030855//epithelial cell differentiation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032532//regulation of microvillus length;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0040018//positive regulation of multicellular organism growth;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045010//actin nucleation;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051125//regulation of actin nucleation;GO:0051693//actin filament capping;GO:0060327//cytoplasmic actin-based contraction involved in cell motility;GO:0061041//regulation of wound healing;GO:0065003//protein-containing complex assembly;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1902896//terminal web assembly;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000392//regulation of lamellipodium morphogenesis;GO:2000394//positive regulation of lamellipodium morphogenesis	--
ENSG00000127837	36.09	35.385	42.156	44.948	39.95	43.674	1213	1284	1037	1188	1204	1082	AAMP	angio associated migratory cell protein [Source:HGNC Symbol;Acc:HGNC:18]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0045171//intercellular bridge	GO:0005515//protein binding;GO:0008201//heparin binding	GO:0001525//angiogenesis;GO:0010595//positive regulation of endothelial cell migration;GO:0014909//smooth muscle cell migration;GO:0030154//cell differentiation	--
ENSG00000127838	30.737	32.391	31.521	44.512	33.619	34.91	608	661	460	663	616	516	PNKD	PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane	GO:0004416//hydroxyacylglutathione hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0019243//methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0042053//regulation of dopamine metabolic process;GO:0046929//negative regulation of neurotransmitter secretion;GO:0050884//neuromuscular process controlling posture"	--
ENSG00000127863	1.724	1.911	1.181	1.209	1.102	1.417	154	171	76	78	82	85	TNFRSF19	TNF receptor superfamily member 19 [Source:HGNC Symbol;Acc:HGNC:11915]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05155	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001942//hair follicle development;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade	--
ENSG00000127870	8.99	6.393	6.449	5.788	5.467	7.89	632	451	336	304	326	413	RNF6	ring finger protein 6 [Source:HGNC Symbol;Acc:HGNC:10069]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0030424//axon;GO:0031965//nuclear membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030517//negative regulation of axon extension;GO:0044314//protein K27-linked ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060765//regulation of androgen receptor signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination"	--
ENSG00000127884	42.737	47.477	44.932	51.834	44.597	41.77	1132	1264	879	1017	998	805	ECHS1	"enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Lipid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko00062//Fatty acid elongation;ko00650//Butanoate metabolism"	K07511;K07511;K07511;K07511;K07511;K07511;K07511;K07511;K07511;K07511;K07511	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0043956//3-hydroxypropionyl-CoA dehydratase activity;GO:0120092//crotonyl-CoA hydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000127903	0.35	1.194	0.966	0.472	0.629	0.653	25	39	37	25	38	34	ZNF835	zinc finger protein 835 [Source:HGNC Symbol;Acc:HGNC:34332]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000127914	1.062	0.572	0.793	0.461	0.765	0.592	226	135	91	77	166	95	AKAP9	A-kinase anchoring protein 9 [Source:HGNC Symbol;Acc:HGNC:379]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005801//cis-Golgi network;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008076//voltage-gated potassium channel complex;GO:0034705//potassium channel complex;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044307//dendritic branch;GO:0097060//synaptic membrane;GO:0098978//glutamatergic synapse;GO:0099147//extrinsic component of postsynaptic density membrane	GO:0003677//DNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0044325//transmembrane transporter binding;GO:0060090//molecular adaptor activity	GO:0007020//microtubule nucleation;GO:0007165//signal transduction;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007268//chemical synaptic transmission;GO:0031116//positive regulation of microtubule polymerization;GO:0031503//protein-containing complex localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0051602//response to electrical stimulus;GO:0051661//maintenance of centrosome location;GO:0060306//regulation of membrane repolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071320//cellular response to cAMP;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1903358//regulation of Golgi organization	--
ENSG00000127920	50.415	52.54	48.304	62.003	51.413	53.355	3157	3307	2234	2876	2720	2431	GNG11	G protein subunit gamma 11 [Source:HGNC Symbol;Acc:HGNC:4403]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546;K04546	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000127922	26.054	21.094	21.628	28.705	16.463	27.385	243	202	151	200	130	185	SEM1	SEM1 26S proteasome subunit [Source:HGNC Symbol;Acc:HGNC:10845]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation;Replication and repair"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome;ko03440//Homologous recombination	K10881;K10881;K10881;K10881;K10881;K10881;K10881;K10881;K10881;K10881	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0032039//integrator complex;GO:0032991//protein-containing complex"	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006406//mRNA export from nucleus;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043248//proteasome assembly	--
ENSG00000127928	21.182	24.809	16.642	15.377	15.775	12.66	276	318	159	150.96	178	120	GNGT1	G protein subunit gamma transducin 1 [Source:HGNC Symbol;Acc:HGNC:4411]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04744//Phototransduction	K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548;K04548	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0097381//photoreceptor disc membrane	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0008104//protein localization;GO:0010659//cardiac muscle cell apoptotic process;GO:0042462//eye photoreceptor cell development;GO:0071456//cellular response to hypoxia	--
ENSG00000127946	6.485	5.72	5.135	4.506	4.597	4.161	984	954	630	511	622	503	HIP1	huntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease	K04559;K04559	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030665//clathrin-coated vesicle membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045211//postsynaptic membrane;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098888//extrinsic component of presynaptic membrane;GO:0098890//extrinsic component of postsynaptic membrane;GO:0098978//glutamatergic synapse	"GO:0003779//actin binding;GO:0005154//epidermal growth factor receptor binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0030276//clathrin binding;GO:0032051//clathrin light chain binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0035254//glutamate receptor binding;GO:0035612//AP-2 adaptor complex binding;GO:0035615//clathrin adaptor activity;GO:0042803//protein homodimerization activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007015//actin filament organization;GO:0030100//regulation of endocytosis;GO:0030154//cell differentiation;GO:0042981//regulation of apoptotic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048268//clathrin coat assembly;GO:0050821//protein stabilization;GO:0051897//positive regulation of protein kinase B signaling;GO:0072583//clathrin-dependent endocytosis;GO:0097190//apoptotic signaling pathway;GO:0099637//neurotransmitter receptor transport;GO:2000588//positive regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000127947	18.048	13.315	14.535	11.921	11.639	13.44	1081	799	630	499	566	589	PTPN12	protein tyrosine phosphatase non-receptor type 12 [Source:HGNC Symbol;Acc:HGNC:9645]	-	-	-	-	GO:0002102//podosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0042995//cell projection	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0042246//tissue regeneration;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1901185//negative regulation of ERBB signaling pathway;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000127948	30.449	38.45	42.019	48.889	38.645	46.927	1463	1592	1313	1495	1601	1346	POR	cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0003958//NADPH-hemoprotein reductase activity;GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0005515//protein binding;GO:0008941//nitric oxide dioxygenase activity;GO:0009055//electron transfer activity;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0047726//iron-cytochrome-c reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding"	GO:0003420//regulation of growth plate cartilage chondrocyte proliferation;GO:0006805//xenobiotic metabolic process;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0009437//carnitine metabolic process;GO:0009725//response to hormone;GO:0009812//flavonoid metabolic process;GO:0018393//internal peptidyl-lysine acetylation;GO:0019395//fatty acid oxidation;GO:0022900//electron transport chain;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032770//positive regulation of monooxygenase activity;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043602//nitrate catabolic process;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0045880//positive regulation of smoothened signaling pathway;GO:0046210//nitric oxide catabolic process;GO:0060192//negative regulation of lipase activity;GO:0070988//demethylation;GO:0071371//cellular response to gonadotropin stimulus;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0071548//response to dexamethasone;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0090181//regulation of cholesterol metabolic process;GO:0090346//cellular organofluorine metabolic process	--
ENSG00000127951	0.011	0.023	0.077	0.015	0.013	0.016	1	2	5	1	1	1	FGL2	fibrinogen like 2 [Source:HGNC Symbol;Acc:HGNC:3696]	-	-	-	-	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0008233//peptidase activity	GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0002617//negative regulation of macrophage antigen processing and presentation;GO:0006508//proteolysis;GO:0043381//negative regulation of memory T cell differentiation;GO:0050687//negative regulation of defense response to virus	--
ENSG00000127952	17.479	20.695	20.647	18.212	16.546	15.419	403	480	355	295	329	245	STYXL1	serine/threonine/tyrosine interacting like 1 [Source:HGNC Symbol;Acc:HGNC:18165]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0001691//pseudophosphatase activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0019903//protein phosphatase binding	GO:0006470//protein dephosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035556//intracellular signal transduction;GO:0062030//negative regulation of stress granule assembly;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000127954	0.024	0.01	0.028	0	0.081	0	5	2	1	0	11	0	STEAP4	STEAP4 metalloreductase [Source:HGNC Symbol;Acc:HGNC:21923]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0070062//extracellular exosome	GO:0008823//cupric reductase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0052851//ferric-chelate reductase (NADPH) activity;GO:0071949//FAD binding	GO:0006811//ion transport;GO:0015677//copper ion import;GO:0022900//electron transport chain;GO:0033212//iron import into cell;GO:0045444//fat cell differentiation;GO:0055072//iron ion homeostasis;GO:0070207//protein homotrimerization	--
ENSG00000127955	18.892	18.037	20.683	18.988	18.106	19.478	1007	905	782	716	770	752	GNAI1	G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Immune system;Substance dependence;Development and regeneration;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Signal transduction;Endocrine system;Immune system;Nervous system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Infectious disease: parasitic;Endocrine system;Environmental adaptation;Endocrine system;Substance dependence;Cellular community - eukaryotes;Nervous system;Infectious disease: bacterial;Digestive system;Endocrine system;Endocrine system;Nervous system;Substance dependence	"ko05200//Pathways in cancer;ko05012//Parkinson disease;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko05133//Pertussis;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression;ko05030//Cocaine addiction"	K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630;K04630	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005834//heterotrimeric G-protein complex;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030496//midbody;GO:0070062//extracellular exosome;GO:0099738//cell cortex region;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0019003//GDP binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031821//G protein-coupled serotonin receptor binding;GO:0046872//metal ion binding	GO:0006457//protein folding;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0043434//response to peptide hormone;GO:0043949//regulation of cAMP-mediated signaling;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:1904322//cellular response to forskolin;GO:1904778//positive regulation of protein localization to cell cortex	--
ENSG00000127980	5.82	4.588	5.243	3.858	4.015	4.051	517	412	327	259	305	234	PEX1	peroxisomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8850]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13338	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016887//ATP hydrolysis activity;GO:0044877//protein-containing complex binding	GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0015031//protein transport;GO:0016558//protein import into peroxisome matrix;GO:0060152//microtubule-based peroxisome localization	--
ENSG00000127989	3.931	3.025	3.627	4.146	3.863	3.164	151	137	93	96	109	106	MTERF1	mitochondrial transcription termination factor 1 [Source:HGNC Symbol;Acc:HGNC:21463]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006353//DNA-templated transcription, termination;GO:0006355//regulation of transcription, DNA-templated;GO:0006393//termination of mitochondrial transcription;GO:0032392//DNA geometric change"	--
ENSG00000127990	25.395	21.97	24.131	21.388	23.556	28.51	878	757	618	538	665	712	SGCE	sarcoglycan epsilon [Source:HGNC Symbol;Acc:HGNC:10808]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0042383//sarcolemma;GO:0042995//cell projection	GO:0005509//calcium ion binding	GO:0007160//cell-matrix adhesion;GO:0007517//muscle organ development	--
ENSG00000127993	1.973	1.98	2.179	2.064	1.945	1.816	181	185	150	144	151	123	RBM48	RNA binding motif protein 48 [Source:HGNC Symbol;Acc:HGNC:21785]	-	-	-	-	GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000127995	7.297	6.699	7.356	6.341	6.286	6.152	595	549	443	383	433	365	CASD1	CAS1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16014]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047186//N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	GO:0005975//carbohydrate metabolic process	--
ENSG00000128000	2.17	1.571	1.319	1.601	3.025	1.165	172	122.24	102	94	166	105	ZNF780B	zinc finger protein 780B [Source:HGNC Symbol;Acc:HGNC:33109]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000128011	4.243	4.235	4.669	4.183	4.401	4.925	315	316	256	230	276	266	LRFN1	leucine rich repeat and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29290]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	-	--
ENSG00000128016	1.849	2.471	2.69	2.496	3.332	2.845	67	90	72	67	102	75	ZFP36	ZFP36 ring finger protein [Source:HGNC Symbol;Acc:HGNC:12862]	Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection	K15308;K15308	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0030014//CCR4-NOT complex;GO:0070578//RISC-loading complex;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019957//C-C chemokine binding;GO:0031072//heat shock protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0070063//RNA polymerase binding;GO:0071889//14-3-3 protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006402//mRNA catabolic process;GO:0009611//response to wounding;GO:0010837//regulation of keratinocyte proliferation;GO:0031047//gene silencing by RNA;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0032680//regulation of tumor necrosis factor production;GO:0032703//negative regulation of interleukin-2 production;GO:0032897//negative regulation of viral transcription;GO:0035278//miRNA mediated inhibition of translation;GO:0035556//intracellular signal transduction;GO:0038066//p38MAPK cascade;GO:0042594//response to starvation;GO:0043488//regulation of mRNA stability;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045600//positive regulation of fat cell differentiation;GO:0045616//regulation of keratinocyte differentiation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0050728//negative regulation of inflammatory response;GO:0050779//RNA destabilization;GO:0051028//mRNA transport;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901835//positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA;GO:1902172//regulation of keratinocyte apoptotic process;GO:1904246//negative regulation of polynucleotide adenylyltransferase activity;GO:1904582//positive regulation of intracellular mRNA localization;GO:2000637//positive regulation of gene silencing by miRNA"	--
ENSG00000128039	5.287	5.207	5.647	8.052	5.94	5.483	173.12	225	135.29	175.92	211.49	169.98	SRD5A3	steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko00510//N-Glycan biosynthesis	K12345;K12345;K12345	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0102389//polyprenol reductase activity"	GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0006629//lipid metabolic process;GO:0006702//androgen biosynthetic process;GO:0016095//polyprenol catabolic process;GO:0019348//dolichol metabolic process;GO:0019408//dolichol biosynthetic process;GO:0071704//organic substance metabolic process	--
ENSG00000128040	0	0	0	0	0	0	0	0	0	0	0	0	SPINK2	serine peptidase inhibitor Kazal type 2 [Source:HGNC Symbol;Acc:HGNC:11245]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0031410//cytoplasmic vesicle	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001675//acrosome assembly;GO:0007286//spermatid development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:1900004//negative regulation of serine-type endopeptidase activity	--
ENSG00000128045	12.102	13.77	8.325	5.92	7.713	4.68	494	565	251	179	266	139	RASL11B	RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway	--
ENSG00000128050	32.837	31.184	32.989	27.192	29.498	28.69	2317	2214	1715	1405	1752	1443	PAICS	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01587;K01587	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004638//phosphoribosylaminoimidazole carboxylase activity;GO:0004639//phosphoribosylaminoimidazolesuccinocarboxamide synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0043727//5-amino-4-imidazole carboxylate lyase activity;GO:0045296//cadherin binding	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0008152//metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000128052	5.538	5.205	4.286	8.971	9.715	12.723	670	633	383	804	993	1120	KDR	kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Drug resistance: antineoplastic;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05418//Fluid shear stress and atherosclerosis;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04370//VEGF signaling pathway	K05098;K05098;K05098;K05098;K05098;K05098;K05098;K05098;K05098;K05098	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0071944//cell periphery;GO:0097443//sorting endosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0038085//vascular endothelial growth factor binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051879//Hsp90 protein binding	GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001945//lymph vessel development;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003157//endocardium development;GO:0003158//endothelium development;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010595//positive regulation of endothelial cell migration;GO:0010629//negative regulation of gene expression;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016239//positive regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0033674//positive regulation of kinase activity;GO:0035162//embryonic hemopoiesis;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043129//surfactant homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0043491//protein kinase B signaling;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045165//cell fate commitment;GO:0045446//endothelial cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048286//lung alveolus development;GO:0048469//cell maturation;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050927//positive regulation of positive chemotaxis;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051894//positive regulation of focal adhesion assembly;GO:0051901//positive regulation of mitochondrial depolarization;GO:0055074//calcium ion homeostasis;GO:0061042//vascular wound healing;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090141//positive regulation of mitochondrial fission;GO:1901532//regulation of hematopoietic progenitor cell differentiation;GO:1903010//regulation of bone development;GO:1904881//cellular response to hydrogen sulfide;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000128059	5.532	4.883	4.751	4.083	3.844	5.273	389	345	268	231	248	293	PPAT	phosphoribosyl pyrophosphate amidotransferase [Source:HGNC Symbol;Acc:HGNC:9238]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K00764;K00764;K00764	GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004044//amidophosphoribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0008152//metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000128159	5.378	5.313	6.328	6.457	6.67	6.103	677	672	563	602	690	559	TUBGCP6	tubulin gamma complex associated protein 6 [Source:HGNC Symbol;Acc:HGNC:18127]	-	-	-	-	GO:0000922//spindle pole;GO:0000923//equatorial microtubule organizing center;GO:0000930//gamma-tubulin complex;GO:0000931//gamma-tubulin large complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0008275//gamma-tubulin small complex;GO:0016020//membrane	GO:0008017//microtubule binding;GO:0043015//gamma-tubulin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0031122//cytoplasmic microtubule organization;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle	--
ENSG00000128165	0.561	0.561	0.275	0.216	0.227	0.961	49	50	18	14	17	62	ADM2	adrenomedullin 2 [Source:HGNC Symbol;Acc:HGNC:28898]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction	K25343;K25343	GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0044877//protein-containing complex binding	GO:0001525//angiogenesis;GO:0003073//regulation of systemic arterial blood pressure;GO:0006468//protein phosphorylation;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007586//digestion;GO:0007631//feeding behavior;GO:0010460//positive regulation of heart rate;GO:0010628//positive regulation of gene expression;GO:0045766//positive regulation of angiogenesis;GO:0045776//negative regulation of blood pressure	--
ENSG00000128185	36.27	42.672	38.616	45.901	40.217	34.295	864.23	1028.24	684.68	820.41	819.52	590.66	DGCR6L	DiGeorge syndrome critical region gene 6 like [Source:HGNC Symbol;Acc:HGNC:18551]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000128191	8.174	8.787	8.185	7.455	8.65	7.073	764	824	565	516	683	481	DGCR8	DGCR8 microprocessor complex subunit [Source:HGNC Symbol;Acc:HGNC:2847]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0070877//microprocessor complex	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0020037//heme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0070878//primary miRNA binding;GO:0140517//protein-RNA adaptor activity	GO:0031053//primary miRNA processing	--
ENSG00000128203	0.987	0.712	0.814	0.908	0.948	1.278	69	50	42	47	56	65	ASPHD2	aspartate beta-hydroxylase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30437]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0018193//peptidyl-amino acid modification	--
ENSG00000128218	0.425	0.592	0.649	0.459	0.403	0.234	5	7	5	4	4	2	VPREB3	V-set pre-B cell surrogate light chain 3 [Source:HGNC Symbol;Acc:HGNC:12710]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	-	GO:0006955//immune response	--
ENSG00000128228	8.883	10.291	10.761	13.254	12.727	11.003	152	177	136	168	184	137	SDF2L1	stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0034663//endoplasmic reticulum chaperone complex;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0051087//chaperone binding;GO:0051117//ATPase binding;GO:0051787//misfolded protein binding	GO:0034976//response to endoplasmic reticulum stress;GO:0042981//regulation of apoptotic process;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein;GO:0071712//ER-associated misfolded protein catabolic process	--
ENSG00000128242	0.303	0.147	0.04	0.434	0.299	0.489	6	5	1	5	5	8	GAL3ST1	galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism	K01019;K01019;K01019	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001733//galactosylceramide sulfotransferase activity;GO:0003824//catalytic activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0050694//galactose 3-O-sulfotransferase activity	GO:0006487//protein N-linked glycosylation;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006681//galactosylceramide metabolic process;GO:0006682//galactosylceramide biosynthetic process;GO:0007283//spermatogenesis;GO:0009247//glycolipid biosynthetic process;GO:0042552//myelination;GO:0046486//glycerolipid metabolic process	--
ENSG00000128245	24.808	24.756	25.966	21.088	18.511	24.77	894	899	685	568	568	652	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle	K16198;K16198;K16198;K16198;K16198;K16198	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0004497//monooxygenase activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0035259//glucocorticoid receptor binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0046982//protein heterodimerization activity	"GO:0002028//regulation of sodium ion transport;GO:0006713//glucocorticoid catabolic process;GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0021762//substantia nigra development;GO:0034613//cellular protein localization;GO:0042921//glucocorticoid receptor signaling pathway;GO:0045664//regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048167//regulation of synaptic plasticity;GO:0050774//negative regulation of dendrite morphogenesis;GO:0086010//membrane depolarization during action potential;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:2000649//regulation of sodium ion transmembrane transporter activity"	--
ENSG00000128250	0	0.128	0	0.174	0.153	0.089	0	4	0	4	4	2	RFPL1	ret finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:9977]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0051782//negative regulation of cell division;GO:2001272//positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis"	--
ENSG00000128253	0	0	0.034	0.081	0.053	0.046	0	0	1	3	2	1	RFPL2	ret finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:9979]	-	-	-	-	GO:0000785//chromatin;GO:0005654//nucleoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000128266	14.6	13.497	15.568	13.079	13.645	18.958	960	892	756	637	758	907	GNAZ	G protein subunit alpha z [Source:HGNC Symbol;Acc:HGNC:4395]	Organismal Systems	Nervous system	ko04730//Long-term depression	K04535	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0044297//cell body	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031821//G protein-coupled serotonin receptor binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0098664//G protein-coupled serotonin receptor signaling pathway	--
ENSG00000128268	2.109	2.33	2.324	1.677	2.423	2.236	236	262	192	139	229	182	MGAT3	"beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7046]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K00737;K00737	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003830//beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006044//N-acetylglucosamine metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0008104//protein localization;GO:0030334//regulation of cell migration;GO:0034599//cellular response to oxidative stress;GO:0050435//amyloid-beta metabolic process;GO:0050890//cognition;GO:1902966//positive regulation of protein localization to early endosome;GO:1905166//negative regulation of lysosomal protein catabolic process	--
ENSG00000128271	0.602	0.38	0.595	0.524	0.762	0.844	22	20	22	17	24	16.17	ADORA2A	adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Substance dependence;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05034//Alcoholism;ko04270//Vascular smooth muscle contraction	K04266;K04266;K04266;K04266;K04266;K04266;K04266	GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030673//axolemma;GO:0032279//asymmetric synapse;GO:0042734//presynaptic membrane;GO:0043025//neuronal cell body;GO:0045211//postsynaptic membrane;GO:0048786//presynaptic active zone;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0110165//cellular anatomical entity	GO:0001609//G protein-coupled adenosine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0051393//alpha-actinin binding	"GO:0001963//synaptic transmission, dopaminergic;GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0001975//response to amphetamine;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007271//synaptic transmission, cholinergic;GO:0007417//central nervous system development;GO:0007596//blood coagulation;GO:0007600//sensory perception;GO:0007626//locomotory behavior;GO:0008015//blood circulation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010035//response to inorganic substance;GO:0014049//positive regulation of glutamate secretion;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission;GO:0014061//regulation of norepinephrine secretion;GO:0014074//response to purine-containing compound;GO:0031000//response to caffeine;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0035249//synaptic transmission, glutamatergic;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0040013//negative regulation of locomotion;GO:0042311//vasodilation;GO:0042755//eating behavior;GO:0043116//negative regulation of vascular permeability;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043279//response to alkaloid;GO:0043524//negative regulation of neuron apoptotic process;GO:0045938//positive regulation of circadian sleep/wake cycle, sleep;GO:0046636//negative regulation of alpha-beta T cell activation;GO:0048143//astrocyte activation;GO:0048812//neuron projection morphogenesis;GO:0050714//positive regulation of protein secretion;GO:0050728//negative regulation of inflammatory response;GO:0050896//response to stimulus;GO:0051881//regulation of mitochondrial membrane potential;GO:0051899//membrane depolarization;GO:0051924//regulation of calcium ion transport;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060080//inhibitory postsynaptic potential;GO:0060134//prepulse inhibition;GO:0110148//biomineralization;GO:1900273//positive regulation of long-term synaptic potentiation;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000128272	109.388	97.735	103.715	91.264	87.447	227.653	3205	2888	2255	2000	2160	4869	ATF4	activating transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:786]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Folding, sorting and degradation;Endocrine and metabolic disease;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Cell growth and death;Endocrine system;Nervous system;Endocrine system;Nervous system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Endocrine system;Aging;Endocrine system;Transport and catabolism;Endocrine system;Substance dependence;Nervous system;Endocrine system;Substance dependence"	"ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04210//Apoptosis;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04137//Mitophagy - animal;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction"	K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374;K04374	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0032590//dendrite membrane;GO:0032991//protein-containing complex;GO:0034399//nuclear periphery;GO:0043005//neuron projection;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990037//Lewy body core;GO:1990589//ATF4-CREB1 transcription factor complex;GO:1990590//ATF1-ATF4 transcription factor complex;GO:1990617//CHOP-ATF4 complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008140//cAMP response element binding protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043522//leucine zipper domain binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140296//general transcription initiation factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006094//gluconeogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006874//cellular calcium ion homeostasis;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007623//circadian rhythm;GO:0009636//response to toxic substance;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0030182//neuron differentiation;GO:0030282//bone mineralization;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031667//response to nutrient levels;GO:0032057//negative regulation of translational initiation in response to stress;GO:0032922//circadian regulation of gene expression;GO:0034198//cellular response to amino acid starvation;GO:0034599//cellular response to oxidative stress;GO:0034644//cellular response to UV;GO:0034976//response to endoplasmic reticulum stress;GO:0035162//embryonic hemopoiesis;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0036499//PERK-mediated unfolded protein response;GO:0042149//cellular response to glucose starvation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043065//positive regulation of apoptotic process;GO:0043267//negative regulation of potassium ion transport;GO:0043525//positive regulation of neuron apoptotic process;GO:0045667//regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0048511//rhythmic process;GO:0061395//positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070169//positive regulation of biomineral tissue development;GO:0070309//lens fiber cell morphogenesis;GO:0070982//L-asparagine metabolic process;GO:0090650//cellular response to oxygen-glucose deprivation;GO:0120163//negative regulation of cold-induced thermogenesis;GO:0140467//integrated stress response signaling;GO:0140468//HRI-mediated signaling;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903351//cellular response to dopamine;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process;GO:1990253//cellular response to leucine starvation;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:1990737//response to manganese-induced endoplasmic reticulum stress;GO:2000120//positive regulation of sodium-dependent phosphate transport"	TF_bZIP
ENSG00000128274	0.452	0.618	0.291	0.529	0.763	0.92	20	26	9	17	27	28	A4GALT	"alpha 1,4-galactosyltransferase (P blood group) [Source:HGNC Symbol;Acc:HGNC:18149]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K01988;K01988;K01988	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0008378//galactosyltransferase activity;GO:0015643//toxic substance binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0050512//lactosylceramide 4-alpha-galactosyltransferase activity	GO:0001576//globoside biosynthetic process;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0007009//plasma membrane organization	--
ENSG00000128276	0	0.04	0.054	0.054	0	0.218	0	1	1	1	0	4	RFPL3	ret finger protein like 3 [Source:HGNC Symbol;Acc:HGNC:9980]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000128283	32.645	33.351	34.224	34.797	35.858	43.135	1380	1410	1020	1120	1285	1337	CDC42EP1	CDC42 effector protein 1 [Source:HGNC Symbol;Acc:HGNC:17014]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005515//protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0098609//cell-cell adhesion	--
ENSG00000128284	0	0	0	0	0.084	0.032	0	0	0	0	3	1	APOL3	apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006869//lipid transport;GO:0006954//inflammatory response;GO:0042157//lipoprotein metabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000128285	0.798	0.914	0.463	0.462	0.54	0.439	35	39	15	15	20	14	MCHR1	melanin concentrating hormone receptor 1 [Source:HGNC Symbol;Acc:HGNC:4479]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04320	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0008022//protein C-terminus binding;GO:0008188//neuropeptide receptor activity;GO:0030273//melanin-concentrating hormone receptor activity;GO:0042277//peptide binding;GO:0042562//hormone binding;GO:0042923//neuropeptide binding	GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0051928//positive regulation of calcium ion transport	--
ENSG00000128294	9.695	10.596	10.247	7.873	7.976	8.486	639	636	515	363	425	371	TPST2	tyrosylprotein sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:12021]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008476//protein-tyrosine sulfotransferase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	GO:0006478//peptidyl-tyrosine sulfation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process	--
ENSG00000128298	0.705	0.573	0.834	0.631	1.081	0.343	30	24	20	19	34	10	BAIAP2L2	BAR/IMD domain containing adaptor protein 2 like 2 [Source:HGNC Symbol;Acc:HGNC:26203]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0044291//cell-cell contact zone;GO:0071439//clathrin complex	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding	GO:0007009//plasma membrane organization;GO:0030838//positive regulation of actin filament polymerization;GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0061024//membrane organization;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000128309	34.133	32.768	39.519	41.838	41.189	41.594	947	925	824	878	984	855	MPST	mercaptopyruvate sulfurtransferase [Source:HGNC Symbol;Acc:HGNC:7223]	Metabolism;Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Amino acid metabolism;Energy metabolism;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00920//Sulfur metabolism;ko04122//Sulfur relay system	K01011;K01011;K01011;K01011	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0004792//thiosulfate sulfurtransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016783//sulfurtransferase activity;GO:0016784//3-mercaptopyruvate sulfurtransferase activity;GO:0042802//identical protein binding	GO:0000098//sulfur amino acid catabolic process;GO:0001822//kidney development;GO:0001889//liver development;GO:0009440//cyanate catabolic process;GO:0009636//response to toxic substance;GO:0019346//transsulfuration;GO:0021510//spinal cord development;GO:0070814//hydrogen sulfide biosynthetic process	--
ENSG00000128310	0	0	0	0	0	0	0	0	0	0	0	0	GALR3	galanin receptor 3 [Source:HGNC Symbol;Acc:HGNC:4134]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04232	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0097730//non-motile cilium	GO:0004930//G protein-coupled receptor activity;GO:0004966//galanin receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007611//learning or memory;GO:0007631//feeding behavior;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090663//galanin-activated signaling pathway"	--
ENSG00000128311	12.722	10.94	12.495	17.167	14.94	16.474	311	267	222	306	301	289	TST	thiosulfate sulfurtransferase [Source:HGNC Symbol;Acc:HGNC:12388]	Metabolism;Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Amino acid metabolism;Energy metabolism;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00920//Sulfur metabolism;ko04122//Sulfur relay system	K01011;K01011;K01011;K01011	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0004792//thiosulfate sulfurtransferase activity;GO:0008097//5S rRNA binding;GO:0016740//transferase activity;GO:0016783//sulfurtransferase activity	GO:0000098//sulfur amino acid catabolic process;GO:0009440//cyanate catabolic process;GO:0019346//transsulfuration;GO:0030855//epithelial cell differentiation;GO:0035928//rRNA import into mitochondrion;GO:0051029//rRNA transport	--
ENSG00000128313	0	0	0	0	0	0	0	0	0	0	0	0	APOL5	apolipoprotein L5 [Source:HGNC Symbol;Acc:HGNC:14869]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process	--
ENSG00000128322	0	0	0	0	0	0	0	0	0	0	0	0	IGLL1	immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	"GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000128335	16.869	19.029	17.356	14.883	15.879	15.185	659	684	498	424	491	406	APOL2	apolipoprotein L2 [Source:HGNC Symbol;Acc:HGNC:619]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006953//acute-phase response;GO:0008203//cholesterol metabolic process;GO:0042157//lipoprotein metabolic process;GO:0060135//maternal process involved in female pregnancy	--
ENSG00000128340	0.098	0.178	0.093	0.133	0.669	0.045	3	5	1	3	14	1	RAC2	Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Neurodegenerative disease;Immune system;Signal transduction;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Immune system;Development and regeneration;Immune system;Signal transduction;Immune system;Cardiovascular disease;Immune system;Cardiovascular disease;Signal transduction;Immune system;Cancer: overview;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Signal transduction	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis;ko04310//Wnt signaling pathway;ko04662//B cell receptor signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration;ko05231//Choline metabolism in cancer;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko04520//Adherens junction;ko04370//VEGF signaling pathway	K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860;K07860	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043020//NADPH oxidase complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding	GO:0006935//chemotaxis;GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0010592//positive regulation of lamellipodium assembly;GO:0010810//regulation of cell-substrate adhesion;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0042129//regulation of T cell proliferation;GO:0043304//regulation of mast cell degranulation;GO:0043652//engulfment of apoptotic cell;GO:0045730//respiratory burst;GO:0050790//regulation of catalytic activity;GO:0060263//regulation of respiratory burst;GO:0060753//regulation of mast cell chemotaxis;GO:0071593//lymphocyte aggregation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:1902622//regulation of neutrophil migration;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000128342	3.125	5.025	1.922	4.582	6.718	3.744	178	214	114	200	258	139	LIF	LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04668//TNF signaling pathway	K05419;K05419;K05419;K05419	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005146//leukemia inhibitory factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001974//blood vessel remodeling;GO:0006955//immune response;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0007275//multicellular organism development;GO:0007566//embryo implantation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030324//lung development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043410//positive regulation of MAPK cascade;GO:0045595//regulation of cell differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045835//negative regulation of meiotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046697//decidualization;GO:0046888//negative regulation of hormone secretion;GO:0048286//lung alveolus development;GO:0048644//muscle organ morphogenesis;GO:0048666//neuron development;GO:0048711//positive regulation of astrocyte differentiation;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0048863//stem cell differentiation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060135//maternal process involved in female pregnancy;GO:0060426//lung vasculature development;GO:0060463//lung lobe morphogenesis;GO:0060707//trophoblast giant cell differentiation;GO:0060708//spongiotrophoblast differentiation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:1900182//positive regulation of protein localization to nucleus;GO:1901676//positive regulation of histone H3-K27 acetylation;GO:1903025//regulation of RNA polymerase II regulatory region sequence-specific DNA binding	--
ENSG00000128346	6.277	7.069	8.689	8.553	8.323	9.423	233	266	242	236	260	256	C22orf23	chromosome 22 open reading frame 23 [Source:HGNC Symbol;Acc:HGNC:18589]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000128383	0	0	0	0	0	0	0	0	0	0	0	0	APOBEC3A	apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016554//cytidine to uridine editing;GO:0044355//clearance of foreign intracellular DNA;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0071466//cellular response to xenobiotic stimulus;GO:0080111//DNA demethylation	--
ENSG00000128394	1.816	1.024	0.758	1.013	0.771	1.153	55	55	29	58	48	34	APOBEC3F	apolipoprotein B mRNA editing enzyme catalytic subunit 3F [Source:HGNC Symbol;Acc:HGNC:17356]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016553//base conversion or substitution editing;GO:0016554//cytidine to uridine editing;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0048525//negative regulation of viral process;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000128408	0.582	0.547	0.175	0.175	0.038	0.267	18	17	4	4	1	6	RIBC2	RIB43A domain with coiled-coils 2 [Source:HGNC Symbol;Acc:HGNC:13241]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000128422	6.197	9.802	5.508	1.802	2.482	2.068	195	310	128	42	64	37	KRT17	keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0071944//cell periphery	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0002009//morphogenesis of an epithelium;GO:0030307//positive regulation of cell growth;GO:0030855//epithelial cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0031424//keratinization;GO:0045109//intermediate filament organization;GO:0045727//positive regulation of translation;GO:0051798//positive regulation of hair follicle development	--
ENSG00000128463	43.765	44.307	47.801	46.325	45.961	55.558	896.9	911.75	722.92	710	755	817	EMC4	ER membrane protein complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28032]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0006915//apoptotic process;GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000128482	0.076	0.045	0.062	0	0.054	0	5	3	3	0	3	0	RNF112	ring finger protein 112 [Source:HGNC Symbol;Acc:HGNC:12968]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0044297//cell body;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007029//endoplasmic reticulum organization;GO:0007399//nervous system development;GO:0016567//protein ubiquitination;GO:0030182//neuron differentiation;GO:0033194//response to hydroperoxide;GO:0036473//cell death in response to oxidative stress;GO:0036474//cell death in response to hydrogen peroxide;GO:0045666//positive regulation of neuron differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0051260//protein homooligomerization;GO:0051726//regulation of cell cycle;GO:0051865//protein autoubiquitination;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:1990403//embryonic brain development	--
ENSG00000128487	40.225	36.909	31.843	20.64	21.958	24.599	2757	2594	1617	1114	1349	1278	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:30615]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0016020//membrane;GO:0031941//filamentous actin;GO:0043231//intracellular membrane-bounded organelle;GO:0045177//apical part of cell	GO:0005515//protein binding	GO:0001824//blastocyst development;GO:0008306//associative learning;GO:0030036//actin cytoskeleton organization	--
ENSG00000128510	13.095	12.231	5.239	9.992	6.887	5.441	309	289	104	153	172	89	CPA4	carboxypeptidase A4 [Source:HGNC Symbol;Acc:HGNC:15740]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0016573//histone acetylation	--
ENSG00000128512	3.41	1.824	1.094	1.1	1.449	1.191	230	149	125	128	128	93	DOCK4	dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17697	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032420//stereocilium;GO:0032421//stereocilium bundle;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0030165//PDZ domain binding;GO:0030971//receptor tyrosine kinase binding;GO:0031267//small GTPase binding	GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity;GO:0060326//cell chemotaxis;GO:1904694//negative regulation of vascular associated smooth muscle contraction;GO:1904754//positive regulation of vascular associated smooth muscle cell migration	--
ENSG00000128513	8.662	7.923	8.068	6.304	7.909	7.63	584	504	371	299	370	306	POT1	protection of telomeres 1 [Source:HGNC Symbol;Acc:HGNC:17284]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070187//shelterin complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0010521//telomerase inhibitor activity;GO:0017151//DEAD/H-box RNA helicase binding;GO:0042162//telomeric DNA binding;GO:0043047//single-stranded telomeric DNA binding;GO:0061821//telomeric D-loop binding;GO:0098505//G-rich strand telomeric DNA binding;GO:1905773//8-hydroxy-2'-deoxyguanosine DNA binding;GO:1990955//G-rich single-stranded DNA binding	GO:0000723//telomere maintenance;GO:0007004//telomere maintenance via telomerase;GO:0016233//telomere capping;GO:0032202//telomere assembly;GO:0032206//positive regulation of telomere maintenance;GO:0032210//regulation of telomere maintenance via telomerase;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032508//DNA duplex unwinding;GO:0051096//positive regulation of helicase activity;GO:0051276//chromosome organization;GO:0051973//positive regulation of telomerase activity;GO:0051974//negative regulation of telomerase activity;GO:0060383//positive regulation of DNA strand elongation;GO:0061820//telomeric D-loop disassembly;GO:0070200//establishment of protein localization to telomere;GO:1905774//regulation of DNA helicase activity;GO:1905776//positive regulation of DNA helicase activity;GO:2001032//regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000128519	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R16	taste 2 receptor member 16 [Source:HGNC Symbol;Acc:HGNC:14921]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000128524	110.289	107.102	113.994	130.364	125.387	122.54	1551	1514	1184	1358	1490	1254	ATP6V1F	ATPase H+ transporting V1 subunit F [Source:HGNC Symbol;Acc:HGNC:16832]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02151;K02151;K02151;K02151;K02151;K02151;K02151;K02151;K02151;K02151	"GO:0000139//Golgi membrane;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0033176//proton-transporting V-type ATPase complex;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0042625//ATPase-coupled ion transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0034220//ion transmembrane transport;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000128534	9.46	11.607	4.866	6.049	2.242	9.223	451	348	277	289	271	309	LSM8	"LSM8 homolog, U6 small nuclear RNA associated [Source:HGNC Symbol;Acc:HGNC:20471]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12627;K12627	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:0120115//Lsm2-8 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0016070//RNA metabolic process"	--
ENSG00000128536	0.007	0.018	0.028	0	0.048	0	1	1	1	0	2	0	CDHR3	cadherin related family member 3 [Source:HGNC Symbol;Acc:HGNC:26308]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0001618//virus receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0046718//viral entry into host cell;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000128563	6.856	8.759	8.363	7.725	9.093	7.999	369.11	439	314	300	403.05	298.01	PRKRIP1	PRKR interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21894]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0070062//extracellular exosome	GO:0003725//double-stranded RNA binding;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0003014//renal system process;GO:0006397//mRNA processing;GO:0006469//negative regulation of protein kinase activity;GO:0008380//RNA splicing;GO:0042326//negative regulation of phosphorylation	--
ENSG00000128564	0	0	0	0	0	0	0	0	0	0	0	0	VGF	VGF nerve growth factor inducible [Source:HGNC Symbol;Acc:HGNC:12684]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0030133//transport vesicle;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0003674//molecular_function;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0008083//growth factor activity	GO:0001541//ovarian follicle development;GO:0002021//response to dietary excess;GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0009409//response to cold;GO:0019953//sexual reproduction;GO:0030073//insulin secretion;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0042593//glucose homeostasis;GO:0042742//defense response to bacterium;GO:0043084//penile erection;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051591//response to cAMP	--
ENSG00000128567	63.818	58.461	66.801	94.844	112.48	126.128	6010	5557	4620	6815	8891	8833	PODXL	podocalyxin like [Source:HGNC Symbol;Acc:HGNC:9171]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K06817	GO:0001726//ruffle;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031528//microvillus membrane;GO:0034451//centriolar satellite;GO:0036057//slit diaphragm;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0016477//cell migration;GO:0022407//regulation of cell-cell adhesion;GO:0022408//negative regulation of cell-cell adhesion;GO:0030335//positive regulation of cell migration;GO:0032534//regulation of microvillus assembly;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0072015//glomerular visceral epithelial cell development;GO:0072175//epithelial tube formation	--
ENSG00000128573	0.451	0.179	0.287	0.166	0.144	0.287	31	15	12	7	10	13	FOXP2	forkhead box P2 [Source:HGNC Symbol;Acc:HGNC:13875]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021757//caudate nucleus development;GO:0021758//putamen development;GO:0021987//cerebral cortex development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048513//animal organ development"	Fork_head
ENSG00000128578	161.9	158.139	161.171	116.077	140.79	129.188	16079	15893	11915	8656	11722	9384	STRIP2	striatin interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:22209]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0016477//cell migration	--
ENSG00000128581	38.65	35.843	35.591	32.863	31.034	38.212	1171	1036.02	761	781	793	836	IFT22	intraflagellar transport 22 [Source:HGNC Symbol;Acc:HGNC:21895]	-	-	-	-	GO:0005813//centrosome;GO:0005929//cilium;GO:0012505//endomembrane system;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0035720//intraciliary anterograde transport;GO:0060271//cilium assembly	--
ENSG00000128585	9.193	6.703	7.366	5.56	6.573	8.105	1193	876	645	491	756	640	MKLN1	muskelin 1 [Source:HGNC Symbol;Acc:HGNC:7109]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0042995//cell projection;GO:0045202//synapse;GO:0098794//postsynapse	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0002090//regulation of receptor internalization;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0031532//actin cytoskeleton reorganization	--
ENSG00000128590	22.375	19.274	19.727	17.967	18.548	20.024	1118	968	728	665	783	728	DNAJB9	DnaJ heat shock protein family (Hsp40) member B9 [Source:HGNC Symbol;Acc:HGNC:6968]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0051087//chaperone binding;GO:0051787//misfolded protein binding	GO:0002639//positive regulation of immunoglobulin production;GO:0006986//response to unfolded protein;GO:0030183//B cell differentiation;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034976//response to endoplasmic reticulum stress;GO:1903895//negative regulation of IRE1-mediated unfolded protein response	--
ENSG00000128591	40.078	39.413	41.955	51.407	54.238	48.711	7612	7521	5886	7231	8703	6732	FLNC	filamin C [Source:HGNC Symbol;Acc:HGNC:3756]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Signal transduction;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko05132//Salmonella infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion	K04437;K04437;K04437;K04437	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030018//Z disc;GO:0042383//sarcolemma;GO:0043034//costamere	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0030506//ankyrin binding;GO:0042802//identical protein binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0045214//sarcomere organization;GO:0055001//muscle cell development	--
ENSG00000128594	0.909	1.254	1.295	1.061	0.913	0.81	65	74	52	46	36	36	LRRC4	leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction	ko04360//Axon guidance;ko04514//Cell adhesion molecules	K16351;K16351	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043197//dendritic spine;GO:0044309//neuron spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0097119//postsynaptic density protein 95 clustering;GO:0099560//synaptic membrane adhesion;GO:1904861//excitatory synapse assembly	--
ENSG00000128595	140.093	136.478	119.103	98.773	107.052	116.771	8857	8458	5587	4516	5591	5372	CALU	calumenin [Source:HGNC Symbol;Acc:HGNC:1458]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0033018//sarcoplasmic reticulum lumen;GO:0042470//melanosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008150//biological_process	--
ENSG00000128596	2.343	1.652	2.662	2.124	2.366	2.249	152	113	99	81	95	78	CCDC136	coiled-coil domain containing 136 [Source:HGNC Symbol;Acc:HGNC:22225]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0001675//acrosome assembly;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0030154//cell differentiation	--
ENSG00000128602	23.178	24.953	27.608	27.064	28.037	23.917	1912	2069	1682	1617	1954	1423	SMO	"smoothened, frizzled class receptor [Source:HGNC Symbol;Acc:HGNC:11119]"	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: overview;Development and regeneration;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K06226;K06226;K06226;K06226;K06226	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0097542//ciliary tip;GO:0097731//9+0 non-motile cilium	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005113//patched binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001570//vasculogenesis;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0001755//neural crest cell migration;GO:0001947//heart looping;GO:0002052//positive regulation of neuroblast proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003007//heart morphogenesis;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0003323//type B pancreatic cell development;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007228//positive regulation of hh target transcription factor activity;GO:0007368//determination of left/right symmetry;GO:0007371//ventral midline determination;GO:0007389//pattern specification process;GO:0007417//central nervous system development;GO:0007494//midgut development;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0021542//dentate gyrus development;GO:0021696//cerebellar cortex morphogenesis;GO:0021794//thalamus development;GO:0021904//dorsal/ventral neural tube patterning;GO:0021910//smoothened signaling pathway involved in ventral spinal cord patterning;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0021953//central nervous system neuron differentiation;GO:0021987//cerebral cortex development;GO:0030335//positive regulation of cell migration;GO:0030857//negative regulation of epithelial cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0034504//protein localization to nucleus;GO:0035264//multicellular organism growth;GO:0040018//positive regulation of multicellular organism growth;GO:0042307//positive regulation of protein import into nucleus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046622//positive regulation of organ growth;GO:0048143//astrocyte activation;GO:0048468//cell development;GO:0048565//digestive tract development;GO:0048568//embryonic organ development;GO:0048589//developmental growth;GO:0048741//skeletal muscle fiber development;GO:0048745//smooth muscle tissue development;GO:0048853//forebrain morphogenesis;GO:0048873//homeostasis of number of cells within a tissue;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050821//protein stabilization;GO:0051451//myoblast migration;GO:0051799//negative regulation of hair follicle development;GO:0060242//contact inhibition;GO:0060413//atrial septum morphogenesis;GO:0060644//mammary gland epithelial cell differentiation;GO:0060684//epithelial-mesenchymal cell signaling;GO:0061053//somite development;GO:0061113//pancreas morphogenesis;GO:0070986//left/right axis specification;GO:0071397//cellular response to cholesterol;GO:0071679//commissural neuron axon guidance;GO:0072285//mesenchymal to epithelial transition involved in metanephric renal vesicle formation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:2000036//regulation of stem cell population maintenance;GO:2000826//regulation of heart morphogenesis"	--
ENSG00000128604	0.79	1.752	1.518	1.161	1.295	0.796	42	56	44	29	46	14	IRF5	interferon regulatory factor 5 [Source:HGNC Symbol;Acc:HGNC:6120]	Organismal Systems	Immune system	ko04620//Toll-like receptor signaling pathway	K09446	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0019221//cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0032494//response to peptidoglycan;GO:0032495//response to muramyl dipeptide;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway"	IRF
ENSG00000128606	9.596	10.125	5.103	3.596	5.108	2.885	409	434	164	113	186	91	LRRC17	leucine rich repeat containing 17 [Source:HGNC Symbol;Acc:HGNC:16895]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0001503//ossification;GO:0045671//negative regulation of osteoclast differentiation;GO:0048539//bone marrow development	--
ENSG00000128607	18.279	16.736	13.654	14.951	13.766	15.67	2119	2132	1336	1259	1475	1333	KLHDC10	kelch domain containing 10 [Source:HGNC Symbol;Acc:HGNC:22194]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0016567//protein ubiquitination;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000128609	42.686	38.452	38.069	32.613	34.983	39.322	1460	1337	1051	906	934	1019	NDUFA5	NADH:ubiquinone oxidoreductase subunit A5 [Source:HGNC Symbol;Acc:HGNC:7688]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949;K03949	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0045271//respiratory chain complex I;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0022904//respiratory electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000128610	0.119	0.02	0.055	0	0	0	6	1	2	0	0	0	FEZF1	FEZ family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:22788]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008285//negative regulation of cell population proliferation;GO:0021537//telencephalon development;GO:0021772//olfactory bulb development;GO:0021797//forebrain anterior/posterior pattern specification;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0043697//cell dedifferentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050767//regulation of neurogenesis"	zf-C2H2
ENSG00000128617	0	0	0	0	0	0	0	0	0	0	0	0	OPN1SW	"opsin 1, short wave sensitive [Source:HGNC Symbol;Acc:HGNC:1012]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0097381//photoreceptor disc membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity;GO:0038023//signaling receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus;GO:0071492//cellular response to UV-A	--
ENSG00000128626	14.73	12.687	16.814	17.808	17.56	15.623	296	256	250	264	296	230	MRPS12	mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380]	Genetic Information Processing	Translation	ko03010//Ribosome	K02950	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000128641	5.374	4.487	3.09	4.187	4.506	3.99	551	463	237	321	393	297	MYO1B	myosin IB [Source:HGNC Symbol;Acc:HGNC:7596]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0010008//endosome membrane;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0030175//filopodium;GO:0031982//vesicle;GO:0032588//trans-Golgi network membrane;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	"GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding"	GO:0006892//post-Golgi vesicle-mediated transport;GO:0007015//actin filament organization;GO:0030048//actin filament-based movement;GO:0030050//vesicle transport along actin filament;GO:0051017//actin filament bundle assembly	--
ENSG00000128645	0	0	0	0	0	0	0	0	0	0	0	0	HOXD1	homeobox D1 [Source:HGNC Symbol;Acc:HGNC:5132]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09301	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019233//sensory perception of pain;GO:0030182//neuron differentiation;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000128652	0	0	0	0	0	0	0	0	0	0	0	0	HOXD3	homeobox D3 [Source:HGNC Symbol;Acc:HGNC:5137]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016235//aggresome;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007160//cell-matrix adhesion;GO:0007219//Notch signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0021615//glossopharyngeal nerve morphogenesis;GO:0030878//thyroid gland development;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0051216//cartilage development"	Homeobox
ENSG00000128654	16.724	16.636	15.9	18.325	14.924	17.509	460	466	323	376	356	358	MTX2	metaxin 2 [Source:HGNC Symbol;Acc:HGNC:7506]	-	-	-	-	GO:0001401//SAM complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0006839//mitochondrial transport;GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization;GO:0015031//protein transport;GO:0045040//protein insertion into mitochondrial outer membrane	--
ENSG00000128655	0.222	0.293	0.325	0.082	0.12	0.064	15	20	14	4	14	3	PDE11A	phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]	Metabolism;Human Diseases;Metabolism;Human Diseases	Global and overview maps;Endocrine and metabolic disease;Nucleotide metabolism;Substance dependence	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00230//Purine metabolism;ko05032//Morphine addiction	K13298;K13298;K13298;K13298	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043204//perikaryon	"GO:0003824//catalytic activity;GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030553//cGMP binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0043951//negative regulation of cAMP-mediated signaling	--
ENSG00000128656	27.674	27.986	25.191	15.956	18.903	21.686	1048	989	706	451	551	521	CHN1	chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046875//ephrin receptor binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008045//motor neuron axon guidance;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0050770//regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000128683	0.154	0.06	0	0	0.035	0.05	7	5	0	0	2	3	GAD1	glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092]	Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nervous system;Endocrine and metabolic disease;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko04727//GABAergic synapse;ko04940//Type I diabetes mellitus;ko00250//Alanine, aspartate and glutamate metabolism;ko00410//beta-Alanine metabolism;ko00650//Butanoate metabolism;ko00430//Taurine and hypotaurine metabolism"	K01580;K01580;K01580;K01580;K01580;K01580;K01580	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0012506//vesicle membrane;GO:0030424//axon;GO:0043679//axon terminus;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0060077//inhibitory synapse;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	GO:0003824//catalytic activity;GO:0004351//glutamate decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006538//glutamate catabolic process;GO:0006540//glutamate decarboxylation to succinate;GO:0007268//chemical synaptic transmission;GO:0018352//protein-pyridoxal-5-phosphate linkage;GO:0019752//carboxylic acid metabolic process;GO:0035176//social behavior;GO:0035641//locomotory exploration behavior;GO:0042136//neurotransmitter biosynthetic process	--
ENSG00000128694	4.753	4.382	5.167	3.854	4.409	5.428	166	176	143	100	126	134	OSGEPL1	O-sialoglycoprotein endopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23075]	-	-	-	-	GO:0005739//mitochondrion	"GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0046872//metal ion binding;GO:0061711//N(6)-L-threonylcarbamoyladenine synthase activity"	GO:0002949//tRNA threonylcarbamoyladenosine modification;GO:0008033//tRNA processing	--
ENSG00000128699	22.857	23.459	24.159	23.664	24.131	27.558	846	871	685	643	724	733	ORMDL1	ORMDL sphingolipid biosynthesis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16036]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035339//SPOTS complex	GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0090155//negative regulation of sphingolipid biosynthetic process;GO:0090156//cellular sphingolipid homeostasis;GO:1900060//negative regulation of ceramide biosynthetic process;GO:2000303//regulation of ceramide biosynthetic process	--
ENSG00000128708	28.303	22.269	22.782	18.209	18.031	20.043	956	756	569	456	515	493	HAT1	histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821]	Organismal Systems;Human Diseases	Immune system;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05034//Alcoholism	K11303;K11303	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016363//nuclear matrix;GO:0032991//protein-containing complex"	GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0010485//H4 histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding	GO:0006323//DNA packaging;GO:0006325//chromatin organization;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006475//internal protein amino acid acetylation;GO:0016573//histone acetylation;GO:0031509//subtelomeric heterochromatin assembly;GO:0043967//histone H4 acetylation	--
ENSG00000128709	0	0	0	0	0.03	0	0	0	0	0	1	0	HOXD9	homeobox D9 [Source:HGNC Symbol;Acc:HGNC:5140]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007338//single fertilization;GO:0007519//skeletal muscle tissue development;GO:0008344//adult locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0030879//mammary gland development;GO:0035115//embryonic forelimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048935//peripheral nervous system neuron development"	Homeobox
ENSG00000128710	0	0	0	0	0	0	0	0	0	0	0	0	HOXD10	homeobox D10 [Source:HGNC Symbol;Acc:HGNC:5133]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer	K09295;K09295	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0017053//transcription repressor complex;GO:0036464//cytoplasmic ribonucleoprotein granule	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007338//single fertilization;GO:0007519//skeletal muscle tissue development;GO:0008344//adult locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0021520//spinal cord motor neuron cell fate specification;GO:0030326//embryonic limb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0045786//negative regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048935//peripheral nervous system neuron development;GO:0050905//neuromuscular process"	Homeobox
ENSG00000128713	0	0	0	0	0	0	0	0	0	0	0	0	HOXD11	homeobox D11 [Source:HGNC Symbol;Acc:HGNC:5134]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009953//dorsal/ventral pattern formation;GO:0048856//anatomical structure development"	Homeobox
ENSG00000128714	0	0.06	0	0.027	0	0.055	0	3	0	1	0	2	HOXD13	homeobox D13 [Source:HGNC Symbol;Acc:HGNC:5136]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0009952//anterior/posterior pattern specification;GO:0022612//gland morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0030539//male genitalia development;GO:0030850//prostate gland development;GO:0033574//response to testosterone;GO:0035108//limb morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042733//embryonic digit morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048619//embryonic hindgut morphogenesis;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060571//morphogenesis of an epithelial fold;GO:0060602//branch elongation of an epithelium;GO:0060687//regulation of branching involved in prostate gland morphogenesis"	Homeobox
ENSG00000128731	10.461	11.119	11.173	9.514	10.909	10.48	3294	3260	2568	2211	2838	2430	HERC2	HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10595	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0032183//SUMO binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006281//DNA repair;GO:0006886//intracellular protein transport;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000128739	148.636	154.596	151.663	151.471	146.806	151.273	4540.7	4736.28	3417.35	3433.31	3784.74	3346.78	SNRPN	small nuclear ribonucleoprotein polypeptide N [Source:HGNC Symbol;Acc:HGNC:11164]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005737//cytoplasm;GO:0030532//small nuclear ribonucleoprotein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071004//U2-type prespliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing"	--
ENSG00000128789	15.3	15.679	16.004	15.875	14.252	17.451	335	348	261	260	264	280	PSMG2	proteasome assembly chaperone 2 [Source:HGNC Symbol;Acc:HGNC:24929]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0043066//negative regulation of apoptotic process;GO:0043248//proteasome assembly;GO:0051131//chaperone-mediated protein complex assembly;GO:0051726//regulation of cell cycle	--
ENSG00000128791	15.749	14.033	13.264	13.897	11.565	15.025	1202	1078	755	784	717	842	TWSG1	twisted gastrulation BMP signaling modulator 1 [Source:HGNC Symbol;Acc:HGNC:12429]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0050431//transforming growth factor beta binding	"GO:0001503//ossification;GO:0001707//mesoderm formation;GO:0001818//negative regulation of cytokine production;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007435//salivary gland morphogenesis;GO:0009888//tissue development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0043010//camera-type eye development;GO:0045668//negative regulation of osteoblast differentiation;GO:2000515//negative regulation of CD4-positive, alpha-beta T cell activation;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000128805	0.731	0.885	0.561	0.89	0.623	1.086	36	43	19	31	26	39	ARHGAP22	Rho GTPase activating protein 22 [Source:HGNC Symbol;Acc:HGNC:30320]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0098978//glutamatergic synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity;GO:0099175//regulation of postsynapse organization	--
ENSG00000128815	0	0	0.006	0.013	0.011	0	0	0	1	2	2	0	WDFY4	WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:29323]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding	"GO:0006914//autophagy;GO:0019882//antigen processing and presentation;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0098586//cellular response to virus"	--
ENSG00000128829	14.107	13.596	12.558	11.644	12.095	11.542	1611	1556	1057	986	1168	958	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:HGNC:19687]	Human Diseases;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases	"Infectious disease: viral;Folding, sorting and degradation;Infectious disease: viral;Transport and catabolism;Infectious disease: viral"	ko05168//Herpes simplex virus 1 infection;ko04141//Protein processing in endoplasmic reticulum;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko05162//Measles	K16196;K16196;K16196;K16196;K16196	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0022626//cytosolic ribosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity;GO:0106310//protein serine kinase activity	GO:0000077//DNA damage checkpoint signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0002230//positive regulation of defense response to virus by host;GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002376//immune system process;GO:0002821//positive regulation of adaptive immune response;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0007612//learning;GO:0007616//long-term memory;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0016310//phosphorylation;GO:0016567//protein ubiquitination;GO:0019081//viral translation;GO:0032057//negative regulation of translational initiation in response to stress;GO:0032792//negative regulation of CREB transcription factor activity;GO:0034198//cellular response to amino acid starvation;GO:0034644//cellular response to UV;GO:0036492//eiF2alpha phosphorylation in response to endoplasmic reticulum stress;GO:0044828//negative regulation by host of viral genome replication;GO:0045665//negative regulation of neuron differentiation;GO:0045947//negative regulation of translational initiation;GO:0046777//protein autophosphorylation;GO:0051607//defense response to virus;GO:0060259//regulation of feeding behavior;GO:0070417//cellular response to cold;GO:0071264//positive regulation of translational initiation in response to starvation;GO:0140469//GCN2-mediated signaling;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1990138//neuron projection extension;GO:1990253//cellular response to leucine starvation	--
ENSG00000128833	7.227	7.396	4.86	4.818	4.794	4.843	970	854	491	399	538	478	MYO5C	myosin VC [Source:HGNC Symbol;Acc:HGNC:7604]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10357	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0030050//vesicle transport along actin filament	--
ENSG00000128849	39.884	42.479	30.078	20.21	24.83	18.866	5968	6389	3324	2240	3139	2054	CGNL1	cingulin like 1 [Source:HGNC Symbol;Acc:HGNC:25931]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21110	GO:0005923//bicellular tight junction;GO:0016459//myosin complex;GO:0030054//cell junction;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:0150105//protein localization to cell-cell junction	--
ENSG00000128872	0.933	0.729	0.763	0.676	0.741	0.775	177	139	107	95	102	107	TMOD2	tropomodulin 2 [Source:HGNC Symbol;Acc:HGNC:11872]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0030016//myofibril;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0007270//neuron-neuron synaptic transmission;GO:0007399//nervous system development;GO:0007611//learning or memory;GO:0030239//myofibril assembly;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0051694//pointed-end actin filament capping	--
ENSG00000128881	4.253	2.89	3.436	3.45	2.872	3.664	917	656	590	407	564	518	TTBK2	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019894//kinesin binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0051010//microtubule plus-end binding;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0007026//negative regulation of microtubule depolymerization;GO:0007165//signal transduction;GO:0007224//smoothened signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0021549//cerebellum development;GO:0021681//cerebellar granular layer development;GO:0021935//cerebellar granule cell precursor tangential migration;GO:0030030//cell projection organization;GO:0030334//regulation of cell migration;GO:0060271//cilium assembly;GO:1902817//negative regulation of protein localization to microtubule;GO:1904527//negative regulation of microtubule binding	--
ENSG00000128886	1.464	1.199	1.466	1.174	1.142	0.7	53.28	40.38	39.42	31.66	35.13	18.53	ELL3	elongation factor for RNA polymerase II 3 [Source:HGNC Symbol;Acc:HGNC:23113]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0016607//nuclear speck;GO:0030054//cell junction	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding	"GO:0006354//DNA-templated transcription, elongation;GO:0006366//transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048863//stem cell differentiation;GO:0050769//positive regulation of neurogenesis;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000179//positive regulation of neural precursor cell proliferation"	--
ENSG00000128891	7.363	7.05	7.682	8.362	6.573	7.812	252	230	184	202	185	171	CCDC32	coiled-coil domain containing 32 [Source:HGNC Symbol;Acc:HGNC:28295]	-	-	-	-	-	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0044782//cilium organization;GO:0060322//head development	--
ENSG00000128908	3.817	4.021	3.661	3.027	3.541	4.289	502	530	357	296	369	412	INO80	INO80 complex ATPase subunit [Source:HGNC Symbol;Acc:HGNC:26956]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016604//nuclear body;GO:0031011//Ino80 complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0043014//alpha-tubulin binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000070//mitotic sister chromatid segregation;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0030307//positive regulation of cell growth;GO:0033044//regulation of chromosome organization;GO:0034644//cellular response to UV;GO:0042766//nucleosome mobilization;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0070914//UV-damage excision repair;GO:0071479//cellular response to ionizing radiation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000128915	6.504	5.077	5.404	5.508	5.979	5.438	701	623	468	348	461	398	ICE2	interactor of little elongation complex ELL subunit 2 [Source:HGNC Symbol;Acc:HGNC:29885]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0035327//transcriptionally active chromatin;GO:0035363//histone locus body	GO:0005515//protein binding	GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III;GO:0045945//positive regulation of transcription by RNA polymerase III	--
ENSG00000128917	0	0.028	0	0	0	0	0	2	0	0	0	0	DLL4	delta like canonical Notch ligand 4 [Source:HGNC Symbol;Acc:HGNC:2910]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06051;K06051;K06051;K06051;K06051;K06051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001974//blood vessel remodeling;GO:0003180//aortic valve morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003344//pericardium morphogenesis;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0008015//blood circulation;GO:0008285//negative regulation of cell population proliferation;GO:0010596//negative regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0030217//T cell differentiation;GO:0035912//dorsal aorta morphogenesis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045746//negative regulation of Notch signaling pathway;GO:0045747//positive regulation of Notch signaling pathway;GO:0050767//regulation of neurogenesis;GO:0050896//response to stimulus;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0061074//regulation of neural retina development;GO:0061314//Notch signaling involved in heart development;GO:0072554//blood vessel lumenization;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000128918	0	0	0	0.044	0	0.045	0	0	0	1	0	1	ALDH1A2	aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K07249;K07249	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	"GO:0001758//retinal dehydrogenase activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016918//retinal binding"	GO:0001568//blood vessel development;GO:0001822//kidney development;GO:0001889//liver development;GO:0001936//regulation of endothelial cell proliferation;GO:0002138//retinoic acid biosynthetic process;GO:0003007//heart morphogenesis;GO:0006629//lipid metabolic process;GO:0006776//vitamin A metabolic process;GO:0007494//midgut development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009855//determination of bilateral symmetry;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010628//positive regulation of gene expression;GO:0014032//neural crest cell development;GO:0016331//morphogenesis of embryonic epithelium;GO:0021915//neural tube development;GO:0021983//pituitary gland development;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030900//forebrain development;GO:0030902//hindbrain development;GO:0031016//pancreas development;GO:0031076//embryonic camera-type eye development;GO:0032355//response to estradiol;GO:0033189//response to vitamin A;GO:0034097//response to cytokine;GO:0035115//embryonic forelimb morphogenesis;GO:0035799//ureter maturation;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0043010//camera-type eye development;GO:0043065//positive regulation of apoptotic process;GO:0048384//retinoic acid receptor signaling pathway;GO:0048566//embryonic digestive tract development;GO:0048738//cardiac muscle tissue development;GO:0051289//protein homotetramerization;GO:0060324//face development;GO:0071300//cellular response to retinoic acid;GO:0090242//retinoic acid receptor signaling pathway involved in somitogenesis	--
ENSG00000128923	4.66	2.66	2.891	2.683	3.198	3.515	827	479	403	361	444	465	MINDY2	MINDY lysine 48 deubiquitinase 2 [Source:HGNC Symbol;Acc:HGNC:26954]	-	-	-	-	GO:0005654//nucleoplasm	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016807//cysteine-type carboxypeptidase activity;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0071795//K11-linked polyubiquitin modification-dependent protein binding;GO:0071796//K6-linked polyubiquitin modification-dependent protein binding;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0008150//biological_process;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000128928	20.932	23.33	22.23	26.798	24.56	22.837	1763	1924	1411	1581	1707	1355	IVD	isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K00253;K00253	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane	"GO:0003824//catalytic activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0004085//butyryl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0008470//isovaleryl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding"	GO:0006082//organic acid metabolic process;GO:0006552//leucine catabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:1901565//organonitrogen compound catabolic process	--
ENSG00000128944	4.031	5.674	5.112	3.646	3.97	4.303	125	141	117	75	104	97	KNSTRN	kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0034451//centriolar satellite;GO:0035371//microtubule plus-end;GO:0072686//mitotic spindle"	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0051010//microtubule plus-end binding	GO:0000070//mitotic sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007059//chromosome segregation;GO:0016477//cell migration;GO:0051301//cell division;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0071364//cellular response to epidermal growth factor stimulus	--
ENSG00000128951	29.403	27.366	24.783	29.249	28.257	30.766	686	706	455	543	573	551	DUT	deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K01520;K01520;K01520	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004170//dUTP diphosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006139//nucleobase-containing compound metabolic process;GO:0006226//dUMP biosynthetic process;GO:0006231//dTMP biosynthetic process;GO:0006260//DNA replication;GO:0009117//nucleotide metabolic process;GO:0046081//dUTP catabolic process	--
ENSG00000128965	1.881	2.196	2.08	1.876	1.459	14.598	57	68	48	42	37	331	CHAC1	ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K07232;K07232	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol	GO:0003839//gamma-glutamylcyclotransferase activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0061928//glutathione specific gamma-glutamylcyclotransferase activity	GO:0006750//glutathione biosynthetic process;GO:0006751//glutathione catabolic process;GO:0006915//apoptotic process;GO:0006986//response to unfolded protein;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0010955//negative regulation of protein processing;GO:0022008//neurogenesis;GO:0045746//negative regulation of Notch signaling pathway;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	--
ENSG00000128973	13.305	13.32	12.982	19.225	15.926	18.119	582.86	578.94	417.97	614.97	597.48	535.9	CLN6	CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077]	-	-	-	-	GO:0005730//nucleolus;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0035727//lysophosphatidic acid binding;GO:0042803//protein homodimerization activity;GO:0120146//sulfatide binding	GO:0001573//ganglioside metabolic process;GO:0007040//lysosome organization;GO:0007042//lysosomal lumen acidification;GO:0007601//visual perception;GO:0008203//cholesterol metabolic process;GO:0030163//protein catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0031987//locomotion involved in locomotory behavior;GO:0044265//cellular macromolecule catabolic process;GO:0045862//positive regulation of proteolysis	--
ENSG00000128989	50.727	52.798	45.516	37.35	39.41	41.076	4925	4104	3368	2737	3359	3180	ARPP19	cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0019212//phosphatase inhibitor activity;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0035308//negative regulation of protein dephosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0045722//positive regulation of gluconeogenesis;GO:0046326//positive regulation of glucose import;GO:0050790//regulation of catalytic activity;GO:0051301//cell division	--
ENSG00000129003	3.343	1.851	2.166	1.376	1.843	2.47	851	487	402	273	411	448	VPS13C	vacuolar protein sorting 13 homolog C [Source:HGNC Symbol;Acc:HGNC:23594]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0032127//dense core granule membrane;GO:0070062//extracellular exosome	-	GO:0006623//protein targeting to vacuole;GO:0006895//Golgi to endosome transport;GO:0007005//mitochondrion organization;GO:0032868//response to insulin;GO:0045053//protein retention in Golgi apparatus;GO:1905090//negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	--
ENSG00000129007	4.933	4.995	4.732	3.459	4.367	3.616	212.42	210.72	151.59	122.78	165.09	111.8	CALML4	calmodulin like 4 [Source:HGNC Symbol;Acc:HGNC:18445]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	-	GO:0005509//calcium ion binding;GO:0030234//enzyme regulator activity	GO:0050790//regulation of catalytic activity	--
ENSG00000129009	3.792	3.162	4.693	2.787	2.936	2.499	136	141	105	68	102	73	ISLR	immunoglobulin superfamily containing leucine rich repeat [Source:HGNC Symbol;Acc:HGNC:6133]	-	-	-	-	GO:0005576//extracellular region;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007155//cell adhesion	--
ENSG00000129028	1.06	1.828	1.722	1.367	1.199	1.36	45	78	54	43	43	42	THAP10	THAP domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23193]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	THAP
ENSG00000129038	79.952	88.306	73.07	89.58	86.16	74.771	3906	4328	2634	3242	3549	2658	LOXL1	lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	"GO:0004720//protein-lysine 6-oxidase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046872//metal ion binding"	GO:0018057//peptidyl-lysine oxidation;GO:0018277//protein deamination;GO:0030199//collagen fibril organization;GO:0032496//response to lipopolysaccharide;GO:0035904//aorta development	--
ENSG00000129048	0	0.062	0.057	0.113	0	0.086	0	3	2	4	0	3	ACKR4	atypical chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:1611]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04186;K04186	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019956//chemokine binding;GO:0019957//C-C chemokine binding	GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000129055	47.889	45.563	45.822	47.604	43.242	50.984	1291.97	1222.43	927.93	936	968.96	1011	ANAPC13	anaphase promoting complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:24540]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K12456;K12456;K12456;K12456;K12456	GO:0005634//nucleus;GO:0005680//anaphase-promoting complex	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000129071	6.873	6.665	6.223	4.881	5.464	5.962	331	323	217	175	220	204	MBD4	"methyl-CpG binding domain 4, DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:6919]"	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10801	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003696//satellite DNA binding;GO:0003824//catalytic activity;GO:0004520//endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0008263//pyrimidine-specific mismatch base pair DNA N-glycosylase activity;GO:0016787//hydrolase activity;GO:0019104//DNA N-glycosylase activity	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0045008//depyrimidination	MBD
ENSG00000129083	47.794	40.285	39.4	30.364	36.267	35.869	3148.82	2677.91	1949	1533	1942.81	1748.74	COPB1	COPI coat complex subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:2231]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0070821//tertiary granule membrane;GO:0097708//intracellular vesicle;GO:0101003//ficolin-1-rich granule membrane	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000129084	57.429	58.704	54.634	55.153	50.779	54.637	1423.42	1476.71	1001	1015	1064.29	985.86	PSMA1	proteasome 20S subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:9530]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02725;K02725;K02725;K02725;K02725;K02725;K02725;K02725	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0005844//polysome;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular exosome"	GO:0001530//lipopolysaccharide binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000129103	87.575	102.804	87.082	102.474	97.038	88.337	3430.57	3950.75	2572.78	2900.89	3172.89	2376.98	SUMF2	sulfatase modifying factor 2 [Source:HGNC Symbol;Acc:HGNC:20415]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	-	--
ENSG00000129116	36.254	34.038	23.886	16.833	19.921	17.275	2884	2663	1388	971	1316	998	PALLD	"palladin, cytoskeletal associated protein [Source:HGNC Symbol;Acc:HGNC:17068]"	-	-	-	-	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0002102//podosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0060076//excitatory synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051371//muscle alpha-actinin binding;GO:0098632//cell-cell adhesion mediator activity	GO:0003334//keratinocyte development;GO:0003382//epithelial cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0070593//dendrite self-avoidance	--
ENSG00000129128	24.544	20.565	18.63	16.952	16.886	17.069	2326	1959	1304	1190	1352	1177	SPCS3	signal peptidase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26212]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K12948	GO:0005783//endoplasmic reticulum;GO:0005787//signal peptidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0019082//viral protein processing;GO:0045047//protein targeting to ER	--
ENSG00000129151	1.782	1.529	0.557	2.301	3.359	1.038	59	56	14	57	95	25	BBOX1	gamma-butyrobetaine hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:964]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K00471;K00471	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008336//gamma-butyrobetaine dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0045329//carnitine biosynthetic process	--
ENSG00000129152	0	0	0	0	0.032	0.037	0	0	0	0	1	1	MYOD1	myogenic differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7611]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K09064	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0030016//myofibril	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007517//muscle organ development;GO:0007518//myoblast fate determination;GO:0007519//skeletal muscle tissue development;GO:0007520//myoblast fusion;GO:0009267//cellular response to starvation;GO:0010468//regulation of gene expression;GO:0014902//myotube differentiation;GO:0014904//myotube cell development;GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0030154//cell differentiation;GO:0035562//negative regulation of chromatin binding;GO:0035914//skeletal muscle cell differentiation;GO:0042693//muscle cell fate commitment;GO:0043403//skeletal muscle tissue regeneration;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0043484//regulation of RNA splicing;GO:0043503//skeletal muscle fiber adaptation;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045445//myoblast differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048741//skeletal muscle fiber development;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0051099//positive regulation of binding;GO:0051146//striated muscle cell differentiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071453//cellular response to oxygen levels;GO:1901741//positive regulation of myoblast fusion;GO:1905382//positive regulation of snRNA transcription by RNA polymerase II;GO:2000818//negative regulation of myoblast proliferation"	bHLH
ENSG00000129158	11.631	11.183	11.268	10.452	9.998	12.771	322	303	218	201	219	233	SERGEF	secretion regulating guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:17499]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050709//negative regulation of protein secretion;GO:0050790//regulation of catalytic activity	--
ENSG00000129159	0.048	0.05	0.062	0.091	0.021	0.152	8	6	6	9	3	11	KCNC1	potassium voltage-gated channel subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:6233]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030673//axolemma;GO:0032589//neuron projection membrane;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0044325//transmembrane transporter binding;GO:0099508//voltage-gated ion channel activity involved in regulation of presynaptic membrane potential	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007420//brain development;GO:0009636//response to toxic substance;GO:0009642//response to light intensity;GO:0010996//response to auditory stimulus;GO:0014075//response to amine;GO:0021549//cerebellum development;GO:0021759//globus pallidus development;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0034767//positive regulation of ion transmembrane transport;GO:0035864//response to potassium ion;GO:0051260//protein homooligomerization;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0071466//cellular response to xenobiotic stimulus;GO:0071774//response to fibroblast growth factor;GO:0071805//potassium ion transmembrane transport;GO:0099505//regulation of presynaptic membrane potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity;GO:1990089//response to nerve growth factor	--
ENSG00000129167	0	0.01	0.014	0	0.059	0.075	0	1	1	0	5	5	TPH1	tryptophan hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:12008]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Nervous system;Amino acid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko00380//Tryptophan metabolism;ko00790//Folate biosynthesis	K00502;K00502;K00502;K00502	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043005//neuron projection	"GO:0004497//monooxygenase activity;GO:0004510//tryptophan 5-monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046872//metal ion binding"	GO:0002576//platelet degranulation;GO:0007623//circadian rhythm;GO:0009072//aromatic amino acid family metabolic process;GO:0030279//negative regulation of ossification;GO:0035902//response to immobilization stress;GO:0042427//serotonin biosynthetic process;GO:0045600//positive regulation of fat cell differentiation;GO:0046849//bone remodeling;GO:0060749//mammary gland alveolus development;GO:1900046//regulation of hemostasis	--
ENSG00000129170	0	0.048	0	0.051	0.182	0.103	0	1	0	1	3	2	CSRP3	cysteine and glycine rich protein 3 [Source:HGNC Symbol;Acc:HGNC:2472]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030017//sarcomere;GO:0030018//Z disc	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0031433//telethonin binding;GO:0042802//identical protein binding;GO:0042805//actinin binding;GO:0046872//metal ion binding	GO:0002026//regulation of the force of heart contraction;GO:0003300//cardiac muscle hypertrophy;GO:0006874//cellular calcium ion homeostasis;GO:0006954//inflammatory response;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0008286//insulin receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0033292//T-tubule organization;GO:0033365//protein localization to organelle;GO:0035995//detection of muscle stretch;GO:0042593//glucose homeostasis;GO:0045214//sarcomere organization;GO:0045663//positive regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048738//cardiac muscle tissue development;GO:0055003//cardiac myofibril assembly;GO:0060048//cardiac muscle contraction;GO:0060537//muscle tissue development;GO:0070528//protein kinase C signaling;GO:1903076//regulation of protein localization to plasma membrane;GO:1903920//positive regulation of actin filament severing	--
ENSG00000129173	0.553	0.215	0.342	0.597	0.853	0.661	40	13	18	34	39	21	E2F8	E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001890//placenta development;GO:0002040//sprouting angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0008283//cell population proliferation;GO:0032466//negative regulation of cytokinesis;GO:0032877//positive regulation of DNA endoreduplication;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060707//trophoblast giant cell differentiation;GO:0060718//chorionic trophoblast cell differentiation;GO:0070365//hepatocyte differentiation"	E2F
ENSG00000129187	69.599	64.493	68.61	79.315	71.455	85.113	2322	2350	1780	1966	2034	2136	DCTD	dCMP deaminase [Source:HGNC Symbol;Acc:HGNC:2710]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K01493;K01493	GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004132//dCMP deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006220//pyrimidine nucleotide metabolic process;GO:0006226//dUMP biosynthetic process;GO:0006231//dTMP biosynthetic process;GO:0008152//metabolic process;GO:0009165//nucleotide biosynthetic process	--
ENSG00000129194	3.38	4.602	3.827	2.241	4.154	2.81	92	116	74	39	85	54	SOX15	SRY-box transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11196]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008584//male gonad development;GO:0009653//anatomical structure morphogenesis;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0030154//cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0045843//negative regulation of striated muscle tissue development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048627//myoblast development;GO:0060707//trophoblast giant cell differentiation;GO:0070318//positive regulation of G0 to G1 transition;GO:2000288//positive regulation of myoblast proliferation"	HMG
ENSG00000129195	0.072	0.194	0.518	0.588	0.502	0.208	2	4	10	12	13	6	PIMREG	PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000129197	15.727	15.335	14.019	13.029	12.54	13.165	404	385	262	260	293	236	RPAIN	RPA interacting protein [Source:HGNC Symbol;Acc:HGNC:28641]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006606//protein import into nucleus;GO:0009411//response to UV	--
ENSG00000129204	0.076	0.059	0.067	0.022	0.051	0.034	14	11	9	3	8	4	USP6	ubiquitin specific peptidase 6 [Source:HGNC Symbol;Acc:HGNC:12629]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0055037//recycling endosome	GO:0003676//nucleic acid binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0060627//regulation of vesicle-mediated transport;GO:0090630//activation of GTPase activity	--
ENSG00000129214	0.547	1.466	1.091	1.303	1.342	1.148	13	31	17	21	27	20	SHBG	sex hormone binding globulin [Source:HGNC Symbol;Acc:HGNC:10839]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0005496//steroid binding;GO:0005497//androgen binding;GO:0005515//protein binding;GO:0008289//lipid binding	-	--
ENSG00000129219	2.591	3.147	3.194	3.052	3.864	3.593	185	220	168	161	169	151	PLD2	phospholipase D2 [Source:HGNC Symbol;Acc:HGNC:9068]	Metabolism;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Transport and catabolism;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Immune system;Signal transduction;Nervous system;Endocrine system;Cancer: overview;Lipid metabolism;Endocrine system;Cancer: specific types;Lipid metabolism	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04024//cAMP signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04071//Sphingolipid signaling pathway;ko04724//Glutamatergic synapse;ko04928//Parathyroid hormone synthesis, secretion and action;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko05212//Pancreatic cancer;ko00565//Ether lipid metabolism"	K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115;K01115	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0098793//presynapse	GO:0003824//catalytic activity;GO:0004630//phospholipase D activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035091//phosphatidylinositol binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007010//cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0016042//lipid catabolic process;GO:0036465//synaptic vesicle recycling;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048017//inositol lipid-mediated signaling;GO:0048870//cell motility	--
ENSG00000129221	0.134	0	0	0	0	0	3	0	0	0	0	0	AIPL1	aryl hydrocarbon receptor interacting protein like 1 [Source:HGNC Symbol;Acc:HGNC:359]	Human Diseases;Human Diseases	Cancer: overview;Endocrine and metabolic disease	ko05207//Chemical carcinogenesis - receptor activation;ko04934//Cushing syndrome	K17767;K17767	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0001918//farnesylated protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0051082//unfolded protein binding	"GO:0000413//protein peptidyl-prolyl isomerization;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0007603//phototransduction, visible light;GO:0018343//protein farnesylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050896//response to stimulus"	--
ENSG00000129226	22.617	23.427	18.124	19.335	15.531	15.915	715	693	454	442	452	346	CD68	CD68 molecule [Source:HGNC Symbol;Acc:HGNC:1693]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K06501	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0007568//aging;GO:0031669//cellular response to nutrient levels;GO:0071222//cellular response to lipopolysaccharide;GO:0072594//establishment of protein localization to organelle;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus	--
ENSG00000129235	13.201	11.257	8.065	8.783	6.707	7.493	261.66	239.58	163.25	166.18	156.88	140.76	TXNDC17	thioredoxin domain containing 17 [Source:HGNC Symbol;Acc:HGNC:28218]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0047134//protein-disulfide reductase (NAD(P)) activity	GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0098869//cellular oxidant detoxification	--
ENSG00000129244	28.003	24.415	28.76	21.098	25.859	25.961	1618	1681	1472	1083	1514	1309	ATP1B2	ATPase Na+/K+ transporting subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:805]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0031253//cell projection membrane;GO:0044298//cell body membrane;GO:0071944//cell periphery;GO:0097449//astrocyte projection;GO:0097450//astrocyte end-foot;GO:0098984//neuron to neuron synapse	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046982//protein heterodimerization activity;GO:0051117//ATPase binding	GO:0001895//retina homeostasis;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0007155//cell adhesion;GO:0010976//positive regulation of neuron projection development;GO:0021670//lateral ventricle development;GO:0021678//third ventricle development;GO:0021944//neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration;GO:0030007//cellular potassium ion homeostasis;GO:0031589//cell-substrate adhesion;GO:0032781//positive regulation of ATPase activity;GO:0036376//sodium ion export across plasma membrane;GO:0045494//photoreceptor cell maintenance;GO:0050821//protein stabilization;GO:0061744//motor behavior;GO:0086009//membrane repolarization;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0120036//plasma membrane bounded cell projection organization;GO:0150104//transport across blood-brain barrier;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:1903976//negative regulation of glial cell migration;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000129245	15.99	17.069	18.16	18.02	17.672	19.565	979	1029	831	827	925	882	FXR2	FMR1 autosomal homolog 2 [Source:HGNC Symbol;Acc:HGNC:4024]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0030424//axon;GO:0030426//growth cone;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044326//dendritic spine neck;GO:0098793//presynapse;GO:1902737//dendritic filopodium	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045182//translation regulator activity;GO:0046982//protein heterodimerization activity	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001934//positive regulation of protein phosphorylation;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation;GO:0051489//regulation of filopodium assembly;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000129250	54.868	46.768	51.281	43.634	42.647	39.427	6893	6840	5103	4704	5158	4113	KIF1C	kinesin family member 1C [Source:HGNC Symbol;Acc:HGNC:6317]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0030424//axon;GO:0030425//dendrite;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007018//microtubule-based movement;GO:0016192//vesicle-mediated transport;GO:0030705//cytoskeleton-dependent intracellular transport;GO:1990048//anterograde neuronal dense core vesicle transport;GO:1990049//retrograde neuronal dense core vesicle transport"	--
ENSG00000129255	65.49	60.761	67.801	70.611	73.755	71.784	1390	1376	1078	1232	1350	1154	MPDU1	mannose-P-dolichol utilization defect 1 [Source:HGNC Symbol;Acc:HGNC:7207]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006457//protein folding;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0009312//oligosaccharide biosynthetic process	--
ENSG00000129292	11.121	8.415	9.46	6.487	7.43	8.535	842	639	477	330	458	454	PHF20L1	PHD finger protein 20 like 1 [Source:HGNC Symbol;Acc:HGNC:24280]	-	-	-	-	GO:0005634//nucleus;GO:0044545//NSL complex	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation"	--
ENSG00000129295	1.422	1.733	2.032	2.715	1.768	2.204	74	72	62	51	60	64	DNAAF11	dynein axonemal assembly factor 11 [Source:HGNC Symbol;Acc:HGNC:16725]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0090651//apical cytoplasm;GO:0120293//dynein axonemal particle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0008584//male gonad development;GO:0030317//flagellated sperm motility;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0043393//regulation of protein binding;GO:0044458//motile cilium assembly;GO:0051649//establishment of localization in cell;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0061458//reproductive system development;GO:0061512//protein localization to cilium;GO:0070286//axonemal dynein complex assembly;GO:0090660//cerebrospinal fluid circulation;GO:0120229//protein localization to motile cilium	--
ENSG00000129315	9.416	9.758	5.8	4.37	7.834	7.057	835	806	506	412	613	520	CCNT1	cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15188	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0070691//P-TEFb complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0017069//snRNA binding;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity;GO:0070063//RNA polymerase binding;GO:0097322//7SK snRNA binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0043923//positive regulation by host of viral transcription;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:1900364//negative regulation of mRNA polyadenylation;GO:1903654//phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter;GO:1903655//phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter"	--
ENSG00000129317	2.661	2.234	3.373	1.808	1.728	1.762	352	226	150	146	160	134	PUS7L	pseudouridine synthase 7 like [Source:HGNC Symbol;Acc:HGNC:25276]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity	GO:0001522//pseudouridine synthesis;GO:0009451//RNA modification	--
ENSG00000129347	9.097	11.446	9.581	8.334	11.57	11.28	527.98	565.29	423.83	376.36	440.67	353.22	KRI1	KRI1 homolog [Source:HGNC Symbol;Acc:HGNC:25769]	-	-	-	-	GO:0005730//nucleolus;GO:0030686//90S preribosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000129351	81.136	81.094	84.499	79.618	83.381	78.575	6470	6415	4974	4721	5525	4710	ILF3	interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	"GO:0006468//protein phosphorylation;GO:0017148//negative regulation of translation;GO:0045071//negative regulation of viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051607//defense response to virus"	--
ENSG00000129353	58.291	57.579	58.027	64.412	60.392	58.569	3468	3637	2685	2930	3325	2776	SLC44A2	solute carrier family 44 member 2 [Source:HGNC Symbol;Acc:HGNC:17292]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K15377	GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0015220//choline transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0015871//choline transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0055085//transmembrane transport	--
ENSG00000129354	1.693	2.205	1.622	2.374	3.562	3.04	43	50	26	47	67	50	AP1M2	adaptor related protein complex 1 subunit mu 2 [Source:HGNC Symbol;Acc:HGNC:558]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12393;K12393	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030121//AP-1 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0006903//vesicle targeting;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0110010//basolateral protein secretion	--
ENSG00000129355	2.757	1.514	3.249	3.061	1.344	2.217	66	36	56	54	27	44	CDKN2D	cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790]	Environmental Information Processing;Cellular Processes	Signal transduction;Cell growth and death	ko04068//FoxO signaling pathway;ko04110//Cell cycle	K06623;K06623	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097129//cyclin D2-CDK4 complex	GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000731//DNA synthesis involved in DNA repair;GO:0007049//cell cycle;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell population proliferation;GO:0009411//response to UV;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0032526//response to retinoic acid;GO:0033280//response to vitamin D;GO:0042326//negative regulation of phosphorylation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048102//autophagic cell death;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000129422	7.755	6.969	6.149	4.182	5.119	6.479	714	651	399	311	391	432	MTUS1	microtubule associated scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:29789]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0010758//regulation of macrophage chemotaxis	--
ENSG00000129437	0	0	0	0	0.271	0.063	0	0	0	0	5	1	KLK14	kallikrein related peptidase 14 [Source:HGNC Symbol;Acc:HGNC:6362]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0009566//fertilization;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0048730//epidermis morphogenesis;GO:0070684//seminal clot liquefaction	--
ENSG00000129450	0	0	0	0	0.034	0	0	0	0	0	1	0	SIGLEC9	sialic acid binding Ig like lectin 9 [Source:HGNC Symbol;Acc:HGNC:10878]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K06740	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000129451	4.961	5.51	6.355	12.879	12.411	14.809	175	202	154	352	376	357	KLK10	kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007049//cell cycle	--
ENSG00000129455	0	0	0	0	0	0	0	0	0	0	0	0	KLK8	kallikrein related peptidase 8 [Source:HGNC Symbol;Acc:HGNC:6369]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030141//secretory granule;GO:0097180//serine protease inhibitor complex	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007613//memory;GO:0008219//cell death;GO:0009611//response to wounding;GO:0031642//negative regulation of myelination;GO:0043616//keratinocyte proliferation;GO:0048681//negative regulation of axon regeneration;GO:0048812//neuron projection morphogenesis;GO:0050807//regulation of synapse organization;GO:0050808//synapse organization	--
ENSG00000129460	10.996	11.102	9.898	10.046	9.289	9.568	254	259	168	171	181	160	NGDN	neuroguidin [Source:HGNC Symbol;Acc:HGNC:20271]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0032040//small-subunit processome;GO:0042995//cell projection"	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006417//regulation of translation"	--
ENSG00000129465	0.249	0.123	0.037	0.649	0.183	0.151	4	3	1	7	6	4	RIPK3	receptor interacting serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:10021]	Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Immune system;Cell growth and death;Signal transduction;Immune system	ko05132//Salmonella infection;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis;ko04668//TNF signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K08847;K08847;K08847;K08847;K08847	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0106310//protein serine kinase activity	"GO:0001914//regulation of T cell mediated cytotoxicity;GO:0002819//regulation of adaptive immune response;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010922//positive regulation of phosphatase activity;GO:0010940//positive regulation of necrotic cell death;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0032147//activation of protein kinase activity;GO:0032649//regulation of interferon-gamma production;GO:0033077//T cell differentiation in thymus;GO:0038061//NIK/NF-kappaB signaling;GO:0042981//regulation of apoptotic process;GO:0043029//T cell homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046006//regulation of activated T cell proliferation;GO:0046777//protein autophosphorylation;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0048538//thymus development;GO:0050896//response to stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051351//positive regulation of ligase activity;GO:0051353//positive regulation of oxidoreductase activity;GO:0051607//defense response to virus;GO:0060545//positive regulation of necroptotic process;GO:0070235//regulation of activation-induced cell death of T cells;GO:0070266//necroptotic process;GO:0070301//cellular response to hydrogen peroxide;GO:0097190//apoptotic signaling pathway;GO:0097300//programmed necrotic cell death;GO:0097527//necroptotic signaling pathway;GO:0097528//execution phase of necroptosis;GO:1990000//amyloid fibril formation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000452//regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000129467	0	0.028	0	0.038	0	0	0	2	0	2	0	0	ADCY4	adenylate cyclase 4 [Source:HGNC Symbol;Acc:HGNC:235]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis"	K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044;K08044	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding	GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction	--
ENSG00000129472	9.162	11.141	11.439	9.418	8.712	10.106	507	566	410	400	414	415	RAB2B	"RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0045921//positive regulation of exocytosis;GO:0051607//defense response to virus	--
ENSG00000129473	3.68	3.301	3.648	4.158	3.442	4.66	261.27	233.77	197.05	210.99	206.32	227.13	BCL2L2	BCL2 like 2 [Source:HGNC Symbol;Acc:HGNC:995]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K02163	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0097136//Bcl-2 family protein complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0097718//disordered domain specific binding	GO:0002931//response to ischemia;GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0035795//negative regulation of mitochondrial membrane permeability;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0060011//Sertoli cell proliferation;GO:0071230//cellular response to amino acid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1904646//cellular response to amyloid-beta;GO:1905430//cellular response to glycine;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000129474	14.226	14.432	15.492	16.195	15.794	19.1	1189	1184	981	992	1131	1143	AJUBA	ajuba LIM protein [Source:HGNC Symbol;Acc:HGNC:20250]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16682;K16682	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0045294//alpha-catenin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030032//lamellipodium assembly;GO:0030334//regulation of cell migration;GO:0031047//gene silencing by RNA;GO:0031328//positive regulation of cellular biosynthetic process;GO:0031334//positive regulation of protein-containing complex assembly;GO:0033673//negative regulation of kinase activity;GO:0033674//positive regulation of kinase activity;GO:0034613//cellular protein localization;GO:0035195//gene silencing by miRNA;GO:0035313//wound healing, spreading of epidermal cells;GO:0035331//negative regulation of hippo signaling;GO:0043087//regulation of GTPase activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0046474//glycerophospholipid biosynthetic process;GO:0048041//focal adhesion assembly;GO:1900037//regulation of cellular response to hypoxia;GO:2000637//positive regulation of gene silencing by miRNA"	--
ENSG00000129480	12.744	10.708	14.017	11.588	11.553	12.2	412.81	362.68	331.43	289.36	297.7	324.86	DTD2	D-aminoacyl-tRNA deacylase 2 [Source:HGNC Symbol;Acc:HGNC:20277]	-	-	-	-	GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0051499//D-aminoacyl-tRNA deacylase activity;GO:0051500//D-tyrosyl-tRNA(Tyr) deacylase activity;GO:0106105//Ala-tRNA(Thr) hydrolase activity	GO:0006399//tRNA metabolic process;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000129484	8.065	7.801	6.465	6.299	6.877	6.355	307	298	176	172	214	173	PARP2	poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04210//Apoptosis;ko03410//Base excision repair	K10798;K10798	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0090734//site of DNA damage	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0031491//nucleosome binding;GO:0140294//NAD DNA ADP-ribosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006302//double-strand break repair;GO:0006471//protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus;GO:0016570//histone modification;GO:0018312//peptidyl-serine ADP-ribosylation;GO:0030592//DNA ADP-ribosylation;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901215//negative regulation of neuron death	--
ENSG00000129493	13.447	8.949	12.404	9.471	11.03	10.319	1629	1338.3	1036	854	1037	1025.17	HEATR5A	HEAT repeat containing 5A [Source:HGNC Symbol;Acc:HGNC:20276]	-	-	-	-	GO:0005829//cytosol;GO:0030139//endocytic vesicle	GO:0005515//protein binding	"GO:0006897//endocytosis;GO:0008104//protein localization;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000129514	0.014	0.014	0	0	0.114	0	1	1	0	0	7	0	FOXA1	forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005902//microvillus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0021904//dorsal/ventral neural tube patterning;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0032355//response to estradiol;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0035239//tube morphogenesis;GO:0042445//hormone metabolic process;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0045666//positive regulation of neuron differentiation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048665//neuron fate specification;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051726//regulation of cell cycle;GO:0060425//lung morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060487//lung epithelial cell differentiation;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0060738//epithelial-mesenchymal signaling involved in prostate gland development;GO:0060740//prostate gland epithelium morphogenesis;GO:0060741//prostate gland stromal morphogenesis;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0061144//alveolar secondary septum development;GO:0061448//connective tissue development;GO:0071542//dopaminergic neuron differentiation;GO:1902691//respiratory basal cell differentiation;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin"	Fork_head
ENSG00000129515	24.306	21.005	21.686	18.031	18.506	19.971	1392	1186	901	812	933	810	SNX6	sorting nexin 6 [Source:HGNC Symbol;Acc:HGNC:14970]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17920	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030904//retromer complex;GO:0030905//retromer, tubulation complex;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0097422//tubular endosome"	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0034452//dynactin binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0035091//phosphatidylinositol binding;GO:0042803//protein homodimerization activity	"GO:0006886//intracellular protein transport;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0016241//regulation of macroautophagy;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042147//retrograde transport, endosome to Golgi;GO:0043524//negative regulation of neuron apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:1904646//cellular response to amyloid-beta"	--
ENSG00000129518	19.425	20.404	17.434	15.085	15.46	15.493	525	551	348	302	353	303	EAPP	E2F associated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:19312]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0008284//positive regulation of cell population proliferation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter	--
ENSG00000129521	1.386	2.291	1.301	2.959	2.139	1.517	69	90	54	77	75	51	EGLN3	egl-9 family hypoxia inducible factor 3 [Source:HGNC Symbol;Acc:HGNC:14661]	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09592;K09592;K09592	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0018126//protein hydroxylation;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0042127//regulation of cell population proliferation;GO:0043523//regulation of neuron apoptotic process;GO:0071456//cellular response to hypoxia	--
ENSG00000129534	1.602	0.8	0.944	0.584	0.574	0.846	104	69	65	25	46	27	MIS18BP1	MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome"	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division	MYB
ENSG00000129535	2.131	1.54	0.942	2.065	2.107	1.875	48.22	42.1	26	43	51	34.15	NRL	neural retina leucine zipper [Source:HGNC Symbol;Acc:HGNC:8002]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043522//leucine zipper domain binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0010628//positive regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046548//retinal rod cell development;GO:0050896//response to stimulus"	TF_bZIP
ENSG00000129538	1178.386	1214.094	1353.165	1330.542	1354.23	1560.982	21850	22581	18430	18283	21191	20944	RNASE1	"ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044]"	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004522//ribonuclease A activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016829//lyase activity	"GO:0016070//RNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000129559	52.961	44.114	57.602	56.896	48.59	58.871	676.95	567	543.94	538.73	525	548	NEDD8	NEDD8 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:7732]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008104//protein localization;GO:0009653//anatomical structure morphogenesis;GO:0019941//modification-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0045116//protein neddylation	--
ENSG00000129562	127.506	130.885	136.376	145.017	120.267	131.005	1809	1864	1429	1524	1441	1350	DAD1	defender against cell death 1 [Source:HGNC Symbol;Acc:HGNC:2664]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K12668;K12668;K12668;K12668	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008047//enzyme activator activity	GO:0001824//blastocyst development;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006915//apoptotic process;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0018279//protein N-linked glycosylation via asparagine;GO:0031647//regulation of protein stability;GO:0043066//negative regulation of apoptotic process;GO:0050790//regulation of catalytic activity	--
ENSG00000129566	3.722	4.918	3.286	1.594	2.093	4.187	321	314	247	167	301	210	TEP1	telomerase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:11726]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:1990904//ribonucleoprotein complex"	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0003720//telomerase activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0070034//telomerase RNA binding	GO:0000722//telomere maintenance via recombination;GO:0006278//RNA-dependent DNA biosynthetic process	--
ENSG00000129595	7.815	6.132	8.107	6.648	7.71	7.704	757	597	580	477	631	543	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A [Source:HGNC Symbol;Acc:HGNC:13278]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003674//molecular_function;GO:0008092//cytoskeletal protein binding	GO:0008150//biological_process;GO:0031032//actomyosin structure organization	--
ENSG00000129596	75.074	67.059	100.439	80.973	79.052	97.083	2437	2188	2408	1947	2168	2293	CDO1	cysteine dioxygenase type 1 [Source:HGNC Symbol;Acc:HGNC:1795]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00430//Taurine and hypotaurine metabolism	K00456;K00456;K00456	GO:0005829//cytosol	"GO:0005506//iron ion binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0017172//cysteine dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0000097//sulfur amino acid biosynthetic process;GO:0006534//cysteine metabolic process;GO:0006954//inflammatory response;GO:0007595//lactation;GO:0010243//response to organonitrogen compound;GO:0019448//L-cysteine catabolic process;GO:0033762//response to glucagon;GO:0042412//taurine biosynthetic process;GO:0043200//response to amino acid;GO:0045471//response to ethanol;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP	--
ENSG00000129625	115.361	104.102	120.835	102.032	97.57	116.274	6310	5883	4824	4099	4554.15	4603	REEP5	receptor accessory protein 5 [Source:HGNC Symbol;Acc:HGNC:30077]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007029//endoplasmic reticulum organization;GO:0008150//biological_process;GO:0032386//regulation of intracellular transport;GO:0090158//endoplasmic reticulum membrane organization	--
ENSG00000129636	36.957	37.815	33.123	30.173	33.135	34.332	2128	2182	1460	1271	1579	1480	ITFG1	integrin alpha FG-GAP repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:30697]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	-	-	--
ENSG00000129646	0.25	0.413	0.593	0.405	0.409	0.364	19	15	30	26	23	15	QRICH2	glutamine rich 2 [Source:HGNC Symbol;Acc:HGNC:25326]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0016020//membrane;GO:0031514//motile cilium;GO:0031965//nuclear membrane;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030031//cell projection assembly;GO:0030317//flagellated sperm motility;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000129654	5.479	7.12	4.668	1.635	1.721	1.87	294	384	185	65	78	73	FOXJ1	forkhead box J1 [Source:HGNC Symbol;Acc:HGNC:3816]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002508//central tolerance induction;GO:0002635//negative regulation of germinal center formation;GO:0002897//positive regulation of central B cell tolerance induction;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006959//humoral immune response;GO:0007283//spermatogenesis;GO:0007368//determination of left/right symmetry;GO:0007389//pattern specification process;GO:0007420//brain development;GO:0007507//heart development;GO:0030030//cell projection organization;GO:0030036//actin cytoskeleton organization;GO:0030856//regulation of epithelial cell differentiation;GO:0032053//ciliary basal body organization;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0034613//cellular protein localization;GO:0035082//axoneme assembly;GO:0035089//establishment of apical/basal cell polarity;GO:0035502//metanephric part of ureteric bud development;GO:0042130//negative regulation of T cell proliferation;GO:0044458//motile cilium assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050869//negative regulation of B cell activation;GO:0050900//leukocyte migration;GO:0060271//cilium assembly;GO:0060428//lung epithelium development;GO:0060429//epithelium development;GO:0060972//left/right pattern formation;GO:0072016//glomerular parietal epithelial cell development;GO:0090630//activation of GTPase activity;GO:1901248//positive regulation of lung ciliated cell differentiation"	Fork_head
ENSG00000129657	50.885	53.743	53.362	50.078	49.842	54.954	4911	4950	3797	3549	4155	3714	SEC14L1	SEC14 like lipid binding 1 [Source:HGNC Symbol;Acc:HGNC:10698]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005515//protein binding;GO:0039552//RIG-I binding	GO:0002376//immune system process;GO:0009968//negative regulation of signal transduction;GO:0015871//choline transport;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0045087//innate immune response	--
ENSG00000129667	9.458	9.559	9.359	8.223	8.628	9.472	496	456	372	346	403	362	RHBDF2	rhomboid 5 homolog 2 [Source:HGNC Symbol;Acc:HGNC:20788]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0140318//protein transporter activity	GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006508//proteolysis;GO:0015031//protein transport;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0050708//regulation of protein secretion;GO:0050709//negative regulation of protein secretion	--
ENSG00000129673	0.05	0	0	0.134	0	0	1	0	0	2	0	0	AANAT	aralkylamine N-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:19]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K00669;K00669	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0004059//aralkylamine N-acetyltransferase activity;GO:0004060//arylamine N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0071889//14-3-3 protein binding	GO:0006474//N-terminal protein amino acid acetylation;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009648//photoperiodism;GO:0010043//response to zinc ion;GO:0014070//response to organic cyclic compound;GO:0030187//melatonin biosynthetic process;GO:0032868//response to insulin;GO:0034097//response to cytokine;GO:0034695//response to prostaglandin E;GO:0046219//indolalkylamine biosynthetic process;GO:0046688//response to copper ion;GO:0048511//rhythmic process;GO:0051412//response to corticosterone;GO:0051591//response to cAMP;GO:0051592//response to calcium ion;GO:0071320//cellular response to cAMP;GO:1901652//response to peptide	--
ENSG00000129675	4.817	4.651	4.015	3.566	4.109	3.755	476	462	293	261	343	270	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6 [Source:HGNC Symbol;Acc:HGNC:685]	Cellular Processes;Human Diseases	Cell motility;Cancer: specific types	ko04810//Regulation of actin cytoskeleton;ko05212//Pancreatic cancer	K05729;K05729	GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0030032//lamellipodium assembly;GO:0050790//regulation of catalytic activity	--
ENSG00000129680	1.136	1.218	0.927	0.482	0.688	0.959	98	106	52	32	51	56	MAP7D3	MAP7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25742]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0008017//microtubule binding;GO:0015631//tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0046785//microtubule polymerization	--
ENSG00000129682	10.403	9.306	10.638	10.333	9.871	10.542	493	431	381	355	397	378	FGF13	fibroblast growth factor 13 [Source:HGNC Symbol;Acc:HGNC:3670]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0016328//lateral plasma membrane;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008083//growth factor activity;GO:0017080//sodium channel regulator activity;GO:0030295//protein kinase activator activity;GO:0044325//transmembrane transporter binding;GO:0048487//beta-tubulin binding	GO:0000165//MAPK cascade;GO:0001764//neuron migration;GO:0006814//sodium ion transport;GO:0007026//negative regulation of microtubule depolymerization;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007612//learning;GO:0007613//memory;GO:0021766//hippocampus development;GO:0021795//cerebral cortex cell migration;GO:0032147//activation of protein kinase activity;GO:0045200//establishment of neuroblast polarity;GO:0046785//microtubule polymerization;GO:0048671//negative regulation of collateral sprouting;GO:0072659//protein localization to plasma membrane;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:1904862//inhibitory synapse assembly;GO:1905150//regulation of voltage-gated sodium channel activity	--
ENSG00000129691	14.298	13.53	17.523	14.01	12.95	12.855	750	748	569	506	598	449	ASH2L	"ASH2 like, histone lysine methyltransferase complex subunit [Source:HGNC Symbol;Acc:HGNC:744]"	Human Diseases	Endocrine and metabolic disease	ko04934//Cushing syndrome	K14964	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046872//metal ion binding	GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell population proliferation;GO:0030097//hemopoiesis;GO:0043627//response to estrogen;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051568//histone H3-K4 methylation	--
ENSG00000129696	6.993	6.856	6.293	5.654	5.525	9.101	288.47	303.89	182.33	177.88	203.43	260.93	TTI2	TELO2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:26262]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0070209//ASTRA complex;GO:0110078//TTT complex	-	GO:0050821//protein stabilization;GO:2000003//positive regulation of DNA damage checkpoint	--
ENSG00000129744	0.037	0	0	0	0	0	1	0	0	0	0	0	ART1	ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0031225//anchored component of membrane;GO:0033017//sarcoplasmic reticulum membrane	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106274//NAD+-protein-arginine ADP-ribosyltransferase activity;GO:0106275//NADP+-protein-arginine ADP-ribosyltransferase activity	GO:0006471//protein ADP-ribosylation;GO:0018120//peptidyl-arginine ADP-ribosylation	--
ENSG00000129749	0.208	0.123	0.101	0.201	0.088	0.135	8	5	3	6	3	3	CHRNA10	cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04811	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098981//cholinergic synapse;GO:0099060//integral component of postsynaptic specialization membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005262//calcium channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0010996//response to auditory stimulus;GO:0034220//ion transmembrane transport;GO:0042127//regulation of cell population proliferation;GO:0042391//regulation of membrane potential;GO:0042472//inner ear morphogenesis;GO:0050877//nervous system process;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0051899//membrane depolarization;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport"	--
ENSG00000129757	58.294	63.155	42.157	54.846	55.014	37.81	2011	2237	1068	1442	1621	973	CDKN1C	cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K09993	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001822//kidney development;GO:0001890//placenta development;GO:0007049//cell cycle;GO:0007096//regulation of exit from mitosis;GO:0007346//regulation of mitotic cell cycle;GO:0007568//aging;GO:0030099//myeloid cell differentiation;GO:0030325//adrenal gland development;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033673//negative regulation of kinase activity;GO:0035264//multicellular organism growth;GO:0042326//negative regulation of phosphorylation;GO:0042551//neuron maturation;GO:0043010//camera-type eye development;GO:0043086//negative regulation of catalytic activity;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051726//regulation of cell cycle;GO:0055123//digestive system development;GO:0060065//uterus development;GO:0060255//regulation of macromolecule metabolic process;GO:0060669//embryonic placenta morphogenesis;GO:0071514//genetic imprinting;GO:1902746//regulation of lens fiber cell differentiation;GO:1904030//negative regulation of cyclin-dependent protein kinase activity"	--
ENSG00000129810	0.41	0.628	0.412	0.091	0.109	0.292	16	29	11	3	4	6	SGO1	shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K11580	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton"	GO:0005515//protein binding;GO:0019900//kinase binding	"GO:0000070//mitotic sister chromatid segregation;GO:0006996//organelle organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0010457//centriole-centriole cohesion;GO:0045132//meiotic chromosome segregation;GO:0045143//homologous chromosome segregation;GO:0051177//meiotic sister chromatid cohesion;GO:0051301//cell division;GO:0071962//mitotic sister chromatid cohesion, centromeric"	--
ENSG00000129824	158.663	167.296	144.813	171.434	148.314	137.433	3274	3531	2272	2661	2621	2072	RPS4Y1	ribosomal protein S4 Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:10425]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02987;K02987	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding	GO:0006412//translation;GO:0010467//gene expression	--
ENSG00000129862	0	0	0	0	0	0	0	0	0	0	0	0	VCY1B	variable charge Y-linked 1B [Source:HGNC Symbol;Acc:HGNC:31751]	-	-	-	-	-	GO:0005515//protein binding	GO:0007420//brain development	--
ENSG00000129864	0	0	0	0	0	0	0	0	0	0	0	0	VCY	variable charge Y-linked [Source:HGNC Symbol;Acc:HGNC:12668]	-	-	-	-	-	GO:0005515//protein binding	GO:0007420//brain development	--
ENSG00000129873	0	0	0	0	0	0	0	0	0	0	0	0	CDY2B	chromodomain Y-linked 2B [Source:HGNC Symbol;Acc:HGNC:23921]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004402//histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	"GO:0007283//spermatogenesis;GO:0016573//histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000129910	0.017	0.033	0	0.159	0.04	0.046	1	2	0	7	2	2	CDH15	cadherin 15 [Source:HGNC Symbol;Acc:HGNC:1754]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06809	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0031594//neuromuscular junction;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000129911	6.997	5.597	6.716	11.216	10.354	6.252	243	257	214	286	279	253	KLF16	Kruppel like factor 16 [Source:HGNC Symbol;Acc:HGNC:16857]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007212//dopamine receptor signaling pathway	zf-C2H2
ENSG00000129925	52.6	53.947	56.734	58.85	55.713	54.457	3012	3097	2365	2478	2664	2303	PGAP6	post-glycosylphosphatidylinositol attachment to proteins 6 [Source:HGNC Symbol;Acc:HGNC:17205]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0008150//biological_process	--
ENSG00000129932	3.227	3.591	3.814	4.061	3.658	4.285	118	132	103	110	113	114	DOHH	deoxyhypusine hydroxylase [Source:HGNC Symbol;Acc:HGNC:28662]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0019135//deoxyhypusine monooxygenase activity;GO:0046872//metal ion binding	GO:0008612//peptidyl-lysine modification to peptidyl-hypusine	--
ENSG00000129933	9.523	9.345	11	9.315	9.823	10.348	957	944	765	669	834	712	MAU2	MAU2 sister chromatid cohesion factor [Source:HGNC Symbol;Acc:HGNC:29140]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0032116//SMC loading complex;GO:0090694//Scc2-Scc4 cohesin loading complex	GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007064//mitotic sister chromatid cohesion;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0051301//cell division;GO:0071921//cohesin loading	--
ENSG00000129946	23.294	24.866	24.844	26.118	26.756	27.475	1220	1309	961	1007	1182	1047	SHC2	SHC adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:29869]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune system;Substance dependence;Immune system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Drug resistance: antineoplastic;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction	"ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko01522//Endocrine resistance;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko04370//VEGF signaling pathway"	K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447;K17447	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000129951	6.987	7.692	6.158	6.53	6.747	8.065	289	333	191	216	263	234	PLPPR3	phospholipid phosphatase related 3 [Source:HGNC Symbol;Acc:HGNC:23497]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042577//lipid phosphatase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation	--
ENSG00000129965	0	0	0	0	0	0	0	0	0	0	0	0	INS-IGF2	INS-IGF2 readthrough [Source:HGNC Symbol;Acc:HGNC:33527]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Signal transduction;Transport and catabolism;Cell growth and death;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine system;Endocrine and metabolic disease;Cancer: specific types;Aging;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine and metabolic disease;Endocrine and metabolic disease;Excretory system;Endocrine and metabolic disease	ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko05215//Prostate cancer;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04917//Prolactin signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04930//Type II diabetes mellitus;ko04940//Type I diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption;ko04950//Maturity onset diabetes of the young	K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity	GO:0007165//signal transduction	--
ENSG00000129968	36.93	39.273	40.74	47.195	43.217	42.117	1302	1392	1059	1237	1274	1082	ABHD17A	"abhydrolase domain containing 17A, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:28756]"	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055038//recycling endosome membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099031//anchored component of postsynaptic density membrane;GO:0099033//anchored component of postsynaptic recycling endosome membrane	GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity	GO:0002084//protein depalmitoylation;GO:0072657//protein localization to membrane;GO:0099175//regulation of postsynapse organization;GO:1902817//negative regulation of protein localization to microtubule;GO:1905668//positive regulation of protein localization to endosome	--
ENSG00000129988	0	0	0	0	0.031	0	0	0	0	0	1	0	LBP	lipopolysaccharide binding protein [Source:HGNC Symbol;Acc:HGNC:6517]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: bacterial;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Immune system	ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko04936//Alcoholic liver disease;ko04620//Toll-like receptor signaling pathway	K05399;K05399;K05399;K05399;K05399	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0070891//lipoteichoic acid binding;GO:0071723//lipopeptide binding	GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0006869//lipid transport;GO:0006953//acute-phase response;GO:0006968//cellular defense response;GO:0008228//opsonization;GO:0015920//lipopolysaccharide transport;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032490//detection of molecule of bacterial origin;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033036//macromolecule localization;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0042742//defense response to bacterium;GO:0043032//positive regulation of macrophage activation;GO:0045087//innate immune response;GO:0045919//positive regulation of cytolysis;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0090023//positive regulation of neutrophil chemotaxis	--
ENSG00000129990	0.321	0.493	0.851	0.691	0.262	0.266	12	13	21	21	12	11	SYT5	synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0070382//exocytic vesicle;GO:0099066//integral component of neuronal dense core vesicle membrane;GO:1990769//proximal neuron projection	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	GO:0007268//chemical synaptic transmission;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0071277//cellular response to calcium ion	--
ENSG00000129991	0.144	0.574	0.293	0.097	0.512	0.099	2	8	3	1	6	1	TNNI3	"troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947]"	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Cardiovascular disease;Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K12044;K12044;K12044;K12044;K12044;K12044	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005861//troponin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0043292//contractile fiber;GO:0097512//cardiac myofibril;GO:1990584//cardiac Troponin complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019855//calcium channel inhibitor activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030172//troponin C binding;GO:0031014//troponin T binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0001570//vasculogenesis;GO:0001980//regulation of systemic arterial blood pressure by ischemic conditions;GO:0003009//skeletal muscle contraction;GO:0006874//cellular calcium ion homeostasis;GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0006940//regulation of smooth muscle contraction;GO:0006941//striated muscle contraction;GO:0007507//heart development;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0030049//muscle filament sliding;GO:0032780//negative regulation of ATPase activity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060047//heart contraction;GO:0060048//cardiac muscle contraction	--
ENSG00000129993	0.096	0.343	0.927	0.42	0.34	0.197	8	18	16	26	24	12	CBFA2T3	CBFA2/RUNX1 partner transcriptional co-repressor 3 [Source:HGNC Symbol;Acc:HGNC:1537]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001666//response to hypoxia;GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0030851//granulocyte differentiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045820//negative regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:1903715//regulation of aerobic respiration"	--
ENSG00000130005	25.333	27.982	27.81	37.471	32.98	27.362	597	654	485	647	648	464	GAMT	guanidinoacetate N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:4136]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00260//Glycine, serine and threonine metabolism"	K00542;K00542;K00542	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0030731//guanidinoacetate N-methyltransferase activity	GO:0006600//creatine metabolic process;GO:0006601//creatine biosynthetic process;GO:0006936//muscle contraction;GO:0007283//spermatogenesis;GO:0009887//animal organ morphogenesis;GO:0032259//methylation;GO:0040014//regulation of multicellular organism growth	--
ENSG00000130021	7.534	7.397	10.79	9.098	8.599	8.444	323	314	277	280	304	268	PUDP	pseudouridine 5'-phosphatase [Source:HGNC Symbol;Acc:HGNC:16818]	-	-	-	-	GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:1990738//pseudouridine 5'-phosphatase activity	GO:0008150//biological_process;GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation	--
ENSG00000130023	5.194	5.572	5.491	5.826	5.535	6.992	161	182	143	128	159	163	ERMARD	ER membrane associated RNA degradation [Source:HGNC Symbol;Acc:HGNC:21056]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000130024	23.93	19.215	19.68	16.159	17.212	19.074	1473.74	1166.15	897	751	853.33	852	PHF10	PHD finger protein 10 [Source:HGNC Symbol;Acc:HGNC:18250]	Human Diseases	Cancer: specific types	ko05225//Hepatocellular carcinoma	K22197	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0071564//npBAF complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000130032	1.064	1.017	5.953	0.823	0.93	1.793	119	121	99	62	93	60	PRRG3	proline rich and Gla domain 3 [Source:HGNC Symbol;Acc:HGNC:30798]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0008150//biological_process	--
ENSG00000130035	0	0	0	0	0	0.037	0	0	0	0	0	1.3	GALNT8	polypeptide N-acetylgalactosaminyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:4130]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing	--
ENSG00000130037	0.563	0.758	0.942	1.118	1.235	1.23	34	46	42	49.97	63	54	KCNA5	potassium voltage-gated channel subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:6224]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0034705//potassium channel complex;GO:0045121//membrane raft;GO:0046691//intracellular canaliculus;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015271//outward rectifier potassium channel activity;GO:0019901//protein kinase binding;GO:0051393//alpha-actinin binding;GO:0086087//voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0086090//voltage-gated potassium channel activity involved in SA node cell action potential repolarization;GO:0097110//scaffold protein binding	GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007219//Notch signaling pathway;GO:0009612//response to mechanical stimulus;GO:0010033//response to organic substance;GO:0019229//regulation of vasoconstriction;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0042542//response to hydrogen peroxide;GO:0043266//regulation of potassium ion transport;GO:0050796//regulation of insulin secretion;GO:0051259//protein complex oligomerization;GO:0051260//protein homooligomerization;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0055093//response to hyperoxia;GO:0060081//membrane hyperpolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086014//atrial cardiac muscle cell action potential;GO:0086050//membrane repolarization during bundle of His cell action potential;GO:0086052//membrane repolarization during SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000288//positive regulation of myoblast proliferation	--
ENSG00000130038	0.053	0.121	0.262	0.08	0.059	0.133	3	7	5	3	3	5	CRACR2A	calcium release activated channel regulator 2A [Source:HGNC Symbol;Acc:HGNC:28657]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031982//vesicle;GO:0032588//trans-Golgi network membrane;GO:0033093//Weibel-Palade body;GO:0035580//specific granule lumen	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0002115//store-operated calcium entry;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0016197//endosomal transport;GO:0032237//activation of store-operated calcium channel activity;GO:0034776//response to histamine;GO:0045063//T-helper 1 cell differentiation;GO:0046330//positive regulation of JNK cascade;GO:0051928//positive regulation of calcium ion transport	--
ENSG00000130045	0.097	0	0.519	0.132	0	0.402	2	0	9	2	0	6	NXNL2	nucleoredoxin like 2 [Source:HGNC Symbol;Acc:HGNC:30482]	-	-	-	-	-	-	GO:0007600//sensory perception;GO:0007601//visual perception;GO:0007608//sensory perception of smell;GO:0045494//photoreceptor cell maintenance	--
ENSG00000130052	1.44	1.712	1.571	1.85	2.12	2.502	144	172	116	137	180	182	STARD8	StAR related lipid transfer domain containing 8 [Source:HGNC Symbol;Acc:HGNC:19161]	-	-	-	-	GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0005096//GTPase activator activity;GO:0008289//lipid binding	GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000130054	0.137	0.253	0.185	0.304	0.243	0.255	14	26	14	23	21	19	NALF2	NALCN channel auxiliary factor 2 [Source:HGNC Symbol;Acc:HGNC:30701]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0015275//stretch-activated, cation-selective, calcium channel activity"	GO:0098703//calcium ion import across plasma membrane	--
ENSG00000130055	0.336	0.346	0.126	0.146	0.086	0	15	15	4	5	3	0	GDPD2	glycerophosphodiester phosphodiesterase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25974]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium	GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047394//glycerophosphoinositol inositolphosphodiesterase activity	GO:0006629//lipid metabolic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0090527//actin filament reorganization	--
ENSG00000130066	29.942	27.839	27.264	29.685	30.144	29.323	652	611	440	480	555	466	SAT1	spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540]	Metabolism;Metabolism;Cellular Processes	Global and overview maps;Amino acid metabolism;Cell growth and death	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko04216//Ferroptosis	K00657;K00657;K00657	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004145//diamine N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019809//spermidine binding;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0006596//polyamine biosynthetic process;GO:0009447//putrescine catabolic process;GO:0032918//spermidine acetylation	--
ENSG00000130119	7.79	5.724	5.747	4.98	5.15	5.799	529	670	480	385	490	458.18	GNL3L	G protein nucleolar 3 like [Source:HGNC Symbol;Acc:HGNC:25553]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14538	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0043232//intracellular non-membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0031334//positive regulation of protein-containing complex assembly;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0033234//negative regulation of protein sumoylation;GO:0042254//ribosome biogenesis;GO:1904816//positive regulation of protein localization to chromosome, telomeric region"	--
ENSG00000130147	14.924	13.318	14.45	14.926	16.043	17.382	1447	1430	1140	1181	1382	1351	SH3BP4	SH3 domain binding protein 4 [Source:HGNC Symbol;Acc:HGNC:10826]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0008285//negative regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0030308//negative regulation of cell growth;GO:0032007//negative regulation of TOR signaling;GO:0034260//negative regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0061462//protein localization to lysosome;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000130150	8.027	6.1	6.359	5.523	4.695	5.937	630	532	341	334	337	360	MOSPD2	motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0044232//organelle membrane contact site;GO:0140284//endoplasmic reticulum-endosome membrane contact site	GO:0005515//protein binding	GO:0006935//chemotaxis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000130158	2.699	4.274	4.374	2.946	3.302	3.048	306	369	259	264	316	240	DOCK6	dedicator of cytokinesis 6 [Source:HGNC Symbol;Acc:HGNC:19189]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000130159	30.67	31.881	34.517	39.822	39.939	44.977	948	1007	792	914	1026	1014	ECSIT	ECSIT signaling integrator [Source:HGNC Symbol;Acc:HGNC:29548]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04405	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002376//immune system process;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0045087//innate immune response;GO:0051341//regulation of oxidoreductase activity;GO:0061635//regulation of protein complex stability	--
ENSG00000130164	14.179	14.282	14.905	20.816	18.997	23.184	1329	1398	1168	1405	1493	1432	LDLR	low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547]	Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Transport and catabolism;Cardiovascular disease;Infectious disease: viral;Endocrine and metabolic disease;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine system;Endocrine system;Digestive system	ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05145//Toxoplasmosis;ko04925//Aldosterone synthesis and secretion;ko04976//Bile secretion;ko04927//Cortisol synthesis and secretion;ko04913//Ovarian steroidogenesis;ko04979//Cholesterol metabolism	K12473;K12473;K12473;K12473;K12473;K12473;K12473;K12473;K12473;K12473	GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0034362//low-density lipoprotein particle;GO:0036020//endolysosome membrane;GO:0036477//somatodendritic compartment;GO:0043235//receptor complex;GO:0045177//apical part of cell;GO:0097443//sorting endosome;GO:1990666//PCSK9-LDLR complex	GO:0001540//amyloid-beta binding;GO:0001618//virus receptor activity;GO:0002020//protease binding;GO:0005041//low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0032050//clathrin heavy chain binding;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding	GO:0001920//negative regulation of receptor recycling;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006909//phagocytosis;GO:0007616//long-term memory;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0015914//phospholipid transport;GO:0030299//intestinal cholesterol absorption;GO:0030301//cholesterol transport;GO:0034381//plasma lipoprotein particle clearance;GO:0034383//low-density lipoprotein particle clearance;GO:0034384//high-density lipoprotein particle clearance;GO:0042157//lipoprotein metabolic process;GO:0042159//lipoprotein catabolic process;GO:0042632//cholesterol homeostasis;GO:0046718//viral entry into host cell;GO:0048844//artery morphogenesis;GO:0050729//positive regulation of inflammatory response;GO:0051246//regulation of protein metabolic process;GO:0051248//negative regulation of protein metabolic process;GO:0061771//response to caloric restriction;GO:0061889//negative regulation of astrocyte activation;GO:0070508//cholesterol import;GO:0071398//cellular response to fatty acid;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0090118//receptor-mediated endocytosis involved in cholesterol transport;GO:0090181//regulation of cholesterol metabolic process;GO:0097242//amyloid-beta clearance;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1903979//negative regulation of microglial cell activation;GO:1905167//positive regulation of lysosomal protein catabolic process;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000130165	20.811	19.488	21.575	24.327	18.541	26.081	437	406	336	379	328	403	ELOF1	elongation factor 1 [Source:HGNC Symbol;Acc:HGNC:28691]	-	-	-	-	GO:0005634//nucleus;GO:0008023//transcription elongation factor complex	GO:0000993//RNA polymerase II complex binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006414//translational elongation	--
ENSG00000130167	0	0	0	0	0	0	0	0	0	0	0	0	TSPAN16	tetraspanin 16 [Source:HGNC Symbol;Acc:HGNC:30725]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000130173	0	0.222	0.13	0	0.113	0	0	2	1	0	1	0	ANGPTL8	angiopoietin like 8 [Source:HGNC Symbol;Acc:HGNC:24933]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22289	GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0010954//positive regulation of protein processing;GO:0019216//regulation of lipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0045444//fat cell differentiation;GO:0048469//cell maturation;GO:0050746//regulation of lipoprotein metabolic process;GO:0070328//triglyceride homeostasis	--
ENSG00000130175	221.837	241.409	250.543	303.504	279.752	240.277	8464	9146	7024	8719	8942	6710	PRKCSH	protein kinase C substrate 80K-H [Source:HGNC Symbol;Acc:HGNC:9411]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K08288	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0017177//glucosidase II complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding	GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0006491//N-glycan processing;GO:0006807//nitrogen compound metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0035556//intracellular signal transduction	--
ENSG00000130176	14.333	19.83	7.805	2.265	3.853	2.166	434	579	173	56	97	49	CNN1	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005925//focal adhesion	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0006940//regulation of smooth muscle contraction;GO:0031032//actomyosin structure organization;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation	--
ENSG00000130177	17.248	18.329	18.619	15.173	16.116	17.071	812	866	653	529	643	586	CDC16	cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03353;K03353;K03353;K03353;K03353	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0072686//mitotic spindle	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000130182	0	0	0	0	0	0	0	0	0	0	0	0	ZSCAN10	zinc finger and SCAN domain containing 10 [Source:HGNC Symbol;Acc:HGNC:12997]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000130193	9.819	13.098	12.595	17.18	14.324	14.886	456	599	432	591	562	503	THEM6	thioesterase superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:29656]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000130202	73.719	72.412	79.332	94.494	97.274	97.477	3549	3672	2846	3504	3883	3287	NECTIN2	nectin cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:9707]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: viral;Signaling molecules and interaction;Cellular community - eukaryotes	ko05168//Herpes simplex virus 1 infection;ko04514//Cell adhesion molecules;ko04520//Adherens junction	K06531;K06531;K06531	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005915//zonula adherens;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043296//apical junction complex;GO:0044291//cell-cell contact zone;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0001675//acrosome assembly;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007286//spermatid development;GO:0007289//spermatid nucleus differentiation;GO:0009566//fertilization;GO:0019062//virion attachment to host cell;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0030382//sperm mitochondrion organization;GO:0032990//cell part morphogenesis;GO:0033005//positive regulation of mast cell activation;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0044406//adhesion of symbiont to host;GO:0044782//cilium organization;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046596//regulation of viral entry into host cell;GO:0046718//viral entry into host cell;GO:0046814//coreceptor-mediated virion attachment to host cell;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051654//establishment of mitochondrion localization;GO:0060370//susceptibility to T cell mediated cytotoxicity	--
ENSG00000130203	708.845	745.269	842.858	822.863	791.501	936.569	16848	17761	14785	14467	15857	16147	APOE	apolipoprotein E [Source:HGNC Symbol;Acc:HGNC:613]	Human Diseases;Organismal Systems	Neurodegenerative disease;Digestive system	ko05010//Alzheimer disease;ko04979//Cholesterol metabolism	K04524;K04524	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0034365//discoidal high-density lipoprotein particle;GO:0042627//chylomicron;GO:0043025//neuronal cell body;GO:0043083//synaptic cleft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle;GO:0098978//glutamatergic synapse;GO:1903561//extracellular vesicle;GO:1990777//lipoprotein particle	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0008289//lipid binding;GO:0016209//antioxidant activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0044877//protein-containing complex binding;GO:0046911//metal chelating activity;GO:0046983//protein dimerization activity;GO:0048156//tau protein binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0071813//lipoprotein particle binding;GO:0120020//cholesterol transfer activity	"GO:0000302//response to reactive oxygen species;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002021//response to dietary excess;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006707//cholesterol catabolic process;GO:0006869//lipid transport;GO:0006874//cellular calcium ion homeostasis;GO:0006898//receptor-mediated endocytosis;GO:0006979//response to oxidative stress;GO:0007010//cytoskeleton organization;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007263//nitric oxide mediated signal transduction;GO:0007271//synaptic transmission, cholinergic;GO:0007616//long-term memory;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010544//negative regulation of platelet activation;GO:0010596//negative regulation of endothelial cell migration;GO:0010629//negative regulation of gene expression;GO:0010873//positive regulation of cholesterol esterification;GO:0010875//positive regulation of cholesterol efflux;GO:0010877//lipid transport involved in lipid storage;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0015909//long-chain fatty acid transport;GO:0017038//protein import;GO:0019068//virion assembly;GO:0019934//cGMP-mediated signaling;GO:0030195//negative regulation of blood coagulation;GO:0030516//regulation of axon extension;GO:0031175//neuron projection development;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034380//high-density lipoprotein particle assembly;GO:0034382//chylomicron remnant clearance;GO:0034384//high-density lipoprotein particle clearance;GO:0034447//very-low-density lipoprotein particle clearance;GO:0035641//locomotory exploration behavior;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042159//lipoprotein catabolic process;GO:0042311//vasodilation;GO:0042632//cholesterol homeostasis;GO:0042981//regulation of apoptotic process;GO:0042982//amyloid precursor protein metabolic process;GO:0043254//regulation of protein-containing complex assembly;GO:0043407//negative regulation of MAP kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0043691//reverse cholesterol transport;GO:0044794//positive regulation by host of viral process;GO:0045088//regulation of innate immune response;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0045807//positive regulation of endocytosis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046889//positive regulation of lipid biosynthetic process;GO:0046907//intracellular transport;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048844//artery morphogenesis;GO:0050709//negative regulation of protein secretion;GO:0050728//negative regulation of inflammatory response;GO:0050790//regulation of catalytic activity;GO:0050807//regulation of synapse organization;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051246//regulation of protein metabolic process;GO:0051651//maintenance of location in cell;GO:0055088//lipid homeostasis;GO:0055089//fatty acid homeostasis;GO:0060999//positive regulation of dendritic spine development;GO:0061136//regulation of proteasomal protein catabolic process;GO:0061771//response to caloric restriction;GO:0070328//triglyceride homeostasis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071830//triglyceride-rich lipoprotein particle clearance;GO:0071831//intermediate-density lipoprotein particle clearance;GO:0072359//circulatory system development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090181//regulation of cholesterol metabolic process;GO:0090209//negative regulation of triglyceride metabolic process;GO:0097006//regulation of plasma lipoprotein particle levels;GO:0097113//AMPA glutamate receptor clustering;GO:0097114//NMDA glutamate receptor clustering;GO:0098869//cellular oxidant detoxification;GO:0120009//intermembrane lipid transfer;GO:1900221//regulation of amyloid-beta clearance;GO:1900223//positive regulation of amyloid-beta clearance;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1902430//negative regulation of amyloid-beta formation;GO:1902952//positive regulation of dendritic spine maintenance;GO:1902991//regulation of amyloid precursor protein catabolic process;GO:1902995//positive regulation of phospholipid efflux;GO:1903002//positive regulation of lipid transport across blood-brain barrier;GO:1905855//positive regulation of heparan sulfate binding;GO:1905860//positive regulation of heparan sulfate proteoglycan binding;GO:1905890//regulation of cellular response to very-low-density lipoprotein particle stimulus;GO:1905906//regulation of amyloid fibril formation;GO:1905907//negative regulation of amyloid fibril formation;GO:1905908//positive regulation of amyloid fibril formation;GO:2000822//regulation of behavioral fear response"	--
ENSG00000130204	23.123	25.495	22.36	24.888	28.982	25.364	796	849	593	659	772	647	TOMM40	translocase of outer mitochondrial membrane 40 [Source:HGNC Symbol;Acc:HGNC:18001]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K11518;K11518	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0046930//pore complex	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0015288//porin activity	GO:0006626//protein targeting to mitochondrion;GO:0006811//ion transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0055085//transmembrane transport	--
ENSG00000130208	16.235	18.754	23.705	23.207	21.488	22.615	191	217	174	200	190	191	APOC1	apolipoprotein C1 [Source:HGNC Symbol;Acc:HGNC:607]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22286	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron	GO:0004859//phospholipase inhibitor activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0031210//phosphatidylcholine binding;GO:0055102//lipase inhibitor activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0010873//positive regulation of cholesterol esterification;GO:0010900//negative regulation of phosphatidylcholine catabolic process;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0032374//regulation of cholesterol transport;GO:0032375//negative regulation of cholesterol transport;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034369//plasma lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034382//chylomicron remnant clearance;GO:0034447//very-low-density lipoprotein particle clearance;GO:0042157//lipoprotein metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045833//negative regulation of lipid metabolic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0050995//negative regulation of lipid catabolic process;GO:0051005//negative regulation of lipoprotein lipase activity	--
ENSG00000130222	0.781	0.781	0.49	0.672	0.555	0.622	17	17	8	11	10	10	GADD45G	growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death;Signal transduction;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04064//NF-kappa B signaling pathway;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05224//Breast cancer;ko05226//Gastric cancer;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402;K04402	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0046330//positive regulation of JNK cascade;GO:0051726//regulation of cell cycle;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000130224	3.309	2.713	2.899	2.405	1.993	2.93	340	280	220	183	173	219	LRCH2	leucine rich repeats and calponin homology domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29292]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000130226	6.734	8.572	5.332	4.846	5.641	3.787	604	741	315	300	406	252	DPP6	dipeptidyl peptidase like 6 [Source:HGNC Symbol;Acc:HGNC:3010]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008236//serine-type peptidase activity;GO:0015459//potassium channel regulator activity	GO:0006508//proteolysis;GO:0072659//protein localization to plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000130227	26.755	25.105	29.817	24.154	27.804	27.635	2601	2549	2057	1749	2092	1933	XPO7	exportin 7 [Source:HGNC Symbol;Acc:HGNC:14108]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K18460	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0051168//nuclear export;GO:0051169//nuclear transport	--
ENSG00000130234	0.7	0.75	0.423	0.409	0.278	0.423	57.3	60.55	29.74	26.06	17.46	22.76	ACE2	angiotensin converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13557]	Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Digestive system;Endocrine system	ko05171//Coronavirus disease - COVID-19;ko04974//Protein digestion and absorption;ko04614//Renin-angiotensin system	K09708;K09708;K09708	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031526//brush border membrane;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001618//virus receptor activity;GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008241//peptidyl-dipeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001817//regulation of cytokine production;GO:0002003//angiotensin maturation;GO:0003051//angiotensin-mediated drinking behavior;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0006508//proteolysis;GO:0015827//tryptophan transport;GO:0019058//viral life cycle;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019229//regulation of vasoconstriction;GO:0022898//regulation of transmembrane transporter activity;GO:0042127//regulation of cell population proliferation;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050727//regulation of inflammatory response;GO:0051957//positive regulation of amino acid transport;GO:0060135//maternal process involved in female pregnancy;GO:0060452//positive regulation of cardiac muscle contraction;GO:0061025//membrane fusion;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0097746//blood vessel diameter maintenance;GO:1903598//positive regulation of gap junction assembly;GO:1903779//regulation of cardiac conduction;GO:1905737//positive regulation of L-proline import across plasma membrane;GO:2000272//negative regulation of signaling receptor activity;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000130244	2.758	2.872	3.121	2.875	4.665	4.239	71	68	55	58	84	84	FAM98C	family with sequence similarity 98 member C [Source:HGNC Symbol;Acc:HGNC:27119]	-	-	-	-	GO:0072669//tRNA-splicing ligase complex	GO:0005515//protein binding	-	--
ENSG00000130254	17.102	14.61	17.734	16.238	16.927	19.202	938.48	878.58	772.13	694.74	803.74	801.97	SAFB2	scaffold attachment factor B2 [Source:HGNC Symbol;Acc:HGNC:21605]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0050684//regulation of mRNA processing;GO:0060008//Sertoli cell differentiation;GO:0060765//regulation of androgen receptor signaling pathway"	--
ENSG00000130255	164.659	173.459	173.851	189.766	144.038	155.339	2086	2212	1630	1781	1544	1438.81	RPL36	ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:13631]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02920;K02920	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000130270	0.203	0.502	0.399	0.246	0.096	0.596	13	28	20	12	6	17	ATP8B3	ATPase phospholipid transporting 8B3 [Source:HGNC Symbol;Acc:HGNC:13535]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity	GO:0006869//lipid transport;GO:0007030//Golgi organization;GO:0007339//binding of sperm to zona pellucida;GO:0015914//phospholipid transport;GO:0045332//phospholipid translocation	--
ENSG00000130283	8.348	8.856	9.278	11.314	9.709	10.753	446.55	476.2	366.55	448.33	438.81	418.52	GDF1	growth differentiation factor 1 [Source:HGNC Symbol;Acc:HGNC:4214]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05495	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction	--
ENSG00000130287	0	0.007	0	0	0	0.021	0	1	0	0	0	2	NCAN	neurocan [Source:HGNC Symbol;Acc:HGNC:2465]	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0012505//endomembrane system;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen	GO:0005509//calcium ion binding;GO:0005540//hyaluronic acid binding;GO:0030246//carbohydrate binding	GO:0001501//skeletal system development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007155//cell adhesion;GO:0007417//central nervous system development	--
ENSG00000130294	77.181	81.263	87.847	78.486	84.341	85.02	13151	13922	11017	10066	12317	10766	KIF1A	kinesin family member 1A [Source:HGNC Symbol;Acc:HGNC:888]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098674//extrinsic component of neuronal dense core vesicle membrane;GO:0098992//neuronal dense core vesicle;GO:0099012//neuronal dense core vesicle membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	GO:0007018//microtubule-based movement;GO:0008089//anterograde axonal transport;GO:0016192//vesicle-mediated transport;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0060998//regulation of dendritic spine development;GO:0061001//regulation of dendritic spine morphogenesis;GO:0099519//dense core granule cytoskeletal transport;GO:1990048//anterograde neuronal dense core vesicle transport;GO:1990049//retrograde neuronal dense core vesicle transport	--
ENSG00000130299	3.12	2.784	2.815	2.687	2.69	2.902	140	139	99	98	120	108	GTPBP3	"GTP binding protein 3, mitochondrial [Source:HGNC Symbol;Acc:HGNC:14880]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0002098//tRNA wobble uridine modification;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation	--
ENSG00000130300	0	0	0	0	0.025	0	0	0	0	0	1	0	PLVAP	plasmalemma vesicle associated protein [Source:HGNC Symbol;Acc:HGNC:13635]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000165//MAPK cascade;GO:0002693//positive regulation of cellular extravasation;GO:0032502//developmental process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043114//regulation of vascular permeability	--
ENSG00000130303	15.749	14.806	16.433	13.134	14.309	13.504	327	309	252	202	251	204	BST2	bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119]	Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral	ko05168//Herpes simplex virus 1 infection;ko05170//Human immunodeficiency virus 1 infection	K06731;K06731	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0002376//immune system process;GO:0002737//negative regulation of plasmacytoid dendritic cell cytokine production;GO:0009615//response to virus;GO:0010951//negative regulation of endopeptidase activity;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0034341//response to interferon-gamma;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0042113//B cell activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0070665//positive regulation of leukocyte proliferation;GO:1901253//negative regulation of intracellular transport of viral material	--
ENSG00000130304	8.787	9.652	10.741	12.645	13.372	11.131	627	678	530	675	763	557	SLC27A1	solute carrier family 27 member 1 [Source:HGNC Symbol;Acc:HGNC:10995]	Human Diseases;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine system;Digestive system	ko04931//Insulin resistance;ko03320//PPAR signaling pathway;ko04975//Fat digestion and absorption	K08745;K08745;K08745	GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0015225//biotin transmembrane transporter activity;GO:0015245//fatty acid transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0042802//identical protein binding;GO:0047676//arachidonate-CoA ligase activity;GO:0090434//oleoyl-CoA ligase activity;GO:1901480//oleate transmembrane transporter activity	GO:0001579//medium-chain fatty acid transport;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006659//phosphatidylserine biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006869//lipid transport;GO:0009409//response to cold;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0015878//biotin transport;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0015911//long-chain fatty acid import across plasma membrane;GO:0031652//positive regulation of heat generation;GO:0032049//cardiolipin biosynthetic process;GO:0032868//response to insulin;GO:0033211//adiponectin-activated signaling pathway;GO:0044381//glucose import in response to insulin stimulus;GO:0044539//long-chain fatty acid import into cell;GO:0071072//negative regulation of phospholipid biosynthetic process;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1905135//biotin import across plasma membrane;GO:1990379//lipid transport across blood-brain barrier	--
ENSG00000130305	4.685	6.201	4.564	6.419	6.835	5.845	190.92	231.38	148.2	182.36	216.6	159.08	NSUN5	NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:16385]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0009383//rRNA (cytosine-C5-)-methyltransferase activity;GO:0016740//transferase activity	GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0014003//oligodendrocyte development;GO:0021987//cerebral cortex development;GO:0022038//corpus callosum development;GO:0031641//regulation of myelination;GO:0032259//methylation;GO:0045727//positive regulation of translation;GO:0050890//cognition;GO:0070475//rRNA base methylation	--
ENSG00000130307	0	0	0	0	0.027	0	0	0	0	0	1	0	USHBP1	USH1 protein network component harmonin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:24058]	-	-	-	-	-	GO:0005515//protein binding;GO:0030165//PDZ domain binding	-	--
ENSG00000130309	14.259	16.765	14.671	14.792	16.476	14.024	1043	1256	813	829	1016	772	COLGALT1	collagen beta(1-O)galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26182]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00514//Other types of O-glycan biosynthesis	K11703;K11703;K11703	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0050211//procollagen galactosyltransferase activity	GO:0030199//collagen fibril organization;GO:1904028//positive regulation of collagen fibril organization	--
ENSG00000130311	16.659	17.042	11.569	17.493	17.498	18.62	558	569	441	473	502	514	DDA1	DET1 and DDB1 associated 1 [Source:HGNC Symbol;Acc:HGNC:28360]	-	-	-	-	GO:0005654//nucleoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000130312	42.451	41.617	51.448	53.098	47.905	59.426	615.11	615.5	557.12	572	586.26	613	MRPL34	mitochondrial ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:14488]	Genetic Information Processing	Translation	ko03010//Ribosome	K02914	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000130313	56.714	54.558	64.186	65.531	63.125	66.859	1168	1131	981	1003	1103	1004	PGLS	6-phosphogluconolactonase [Source:HGNC Symbol;Acc:HGNC:8903]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00030//Pentose phosphate pathway	K01057;K01057;K01057	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0017057//6-phosphogluconolactonase activity	"GO:0005975//carbohydrate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009051//pentose-phosphate shunt, oxidative branch"	--
ENSG00000130332	14.651	14.654	15.722	19.128	13.84	15.024	150	151	119	145	120	112	LSM7	"LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12626;K12626	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0097526//spliceosomal tri-snRNP complex;GO:0120115//Lsm2-8 complex;GO:1990726//Lsm1-7-Pat1 complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000130338	8.422	7.753	7.805	4.495	5.695	6.727	1893	1682	1181	767	1072	1045	TULP4	TUB like protein 4 [Source:HGNC Symbol;Acc:HGNC:15530]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination	Tub
ENSG00000130340	19.938	18.975	18.74	16.586	16.141	18.417	1482	1403	1003	894	1009	991	SNX9	sorting nexin 9 [Source:HGNC Symbol;Acc:HGNC:14973]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K17923	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032437//cuticular plate;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0008289//lipid binding;GO:0031625//ubiquitin protein ligase binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0071933//Arp2/3 complex binding	GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007049//cell cycle;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030838//positive regulation of actin filament polymerization;GO:0036089//cleavage furrow formation;GO:0043547//positive regulation of GTPase activity;GO:0045860//positive regulation of protein kinase activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051301//cell division;GO:0060988//lipid tube assembly;GO:0065003//protein-containing complex assembly;GO:0097320//plasma membrane tubulation	--
ENSG00000130347	1.888	1.543	2.431	2.003	1.626	1.017	88.76	69.56	64.4	67.27	67.51	44.39	RTN4IP1	reticulon 4 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18647]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity	GO:0007399//nervous system development;GO:0050773//regulation of dendrite development	--
ENSG00000130348	5.473	4.793	5.723	4.09	5.36	5.222	459	399	360	258	379	319	QRSL1	glutaminyl-tRNA amidotransferase subunit QRSL1 [Source:HGNC Symbol;Acc:HGNC:21020]	Metabolism;Genetic Information Processing	Global and overview maps;Translation	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis	K02433;K02433	GO:0005739//mitochondrion;GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"	GO:0006412//translation;GO:0031647//regulation of protein stability;GO:0032543//mitochondrial translation;GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation	--
ENSG00000130349	4.986	6.269	4.975	5.431	5.326	5.346	126	156	91	101	110	97	MTRES1	mitochondrial transcription rescue factor 1 [Source:HGNC Symbol;Acc:HGNC:17971]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding	GO:0072344//rescue of stalled ribosome;GO:1903108//regulation of mitochondrial transcription	--
ENSG00000130363	4.487	3.788	3.997	2.712	3.063	2.743	612	493	349	274	353	257	RSPH3	radial spoke head 3 [Source:HGNC Symbol;Acc:HGNC:21054]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0042995//cell projection	-	-	--
ENSG00000130368	0	0	0.006	0	0.006	0	0	0	1	0	1	0	MAS1	"MAS1 proto-oncogene, G protein-coupled receptor [Source:HGNC Symbol;Acc:HGNC:6899]"	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko04614//Renin-angiotensin system	K04303;K04303;K04303	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001595//angiotensin receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding	GO:0001933//negative regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007283//spermatogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0014823//response to activity;GO:0021766//hippocampus development;GO:0034698//response to gonadotropin;GO:0038166//angiotensin-activated signaling pathway;GO:0043434//response to peptide hormone;GO:0045740//positive regulation of DNA replication;GO:0050727//regulation of inflammatory response;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0070528//protein kinase C signaling;GO:0071375//cellular response to peptide hormone stimulus	--
ENSG00000130377	0.058	0	0	0	0	0	3	0	0	0	0	0	ACSBG2	acyl-CoA synthetase bubblegum family member 2 [Source:HGNC Symbol;Acc:HGNC:24174]	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko00061//Fatty acid biosynthesis	K15013;K15013;K15013;K15013;K15013;K15013	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0047676//arachidonate-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042759//long-chain fatty acid biosynthetic process	--
ENSG00000130382	24.297	24.702	23.348	21.959	23.949	20.191	2284	2334	1621	1529	1902	1381	MLLT1	MLLT1 super elongation complex subunit [Source:HGNC Symbol;Acc:HGNC:7134]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15187	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0032783//super elongation complex;GO:0035267//NuA4 histone acetyltransferase complex	GO:0005515//protein binding;GO:0042393//histone binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006469//negative regulation of protein kinase activity;GO:0016573//histone acetylation"	--
ENSG00000130383	0.05	0	0.136	0	0.06	0.069	2	0	4	0	2	2	FUT5	fucosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:4016]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07633;K07633	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process	--
ENSG00000130385	0	0	0	0	0	0	0	0	0	0	0	0	BMP15	bone morphogenetic protein 15 [Source:HGNC Symbol;Acc:HGNC:1068]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04060//Cytokine-cytokine receptor interaction;ko04913//Ovarian steroidogenesis	K05498;K05498	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070698//type I activin receptor binding	GO:0001541//ovarian follicle development;GO:0007292//female gamete generation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060016//granulosa cell development;GO:0060395//SMAD protein signal transduction	--
ENSG00000130396	55.547	42.048	46.574	42.539	44.395	55.728	5459	4658	3830	3536	4170	4447	AFDN	"afadin, adherens junction formation factor [Source:HGNC Symbol;Acc:HGNC:7137]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes	Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune system;Cellular community - eukaryotes	ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04530//Tight junction;ko04670//Leukocyte transendothelial migration;ko04520//Adherens junction	K05702;K05702;K05702;K05702;K05702;K05702	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0044291//cell-cell contact zone;GO:0046930//pore complex;GO:0070160//tight junction	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0051015//actin filament binding	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0010628//positive regulation of gene expression;GO:0022409//positive regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0032880//regulation of protein localization;GO:0043547//positive regulation of GTPase activity;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0046931//pore complex assembly;GO:0048856//anatomical structure development;GO:0061951//establishment of protein localization to plasma membrane;GO:0070830//bicellular tight junction assembly;GO:0090557//establishment of endothelial intestinal barrier;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin	--
ENSG00000130402	177.062	177.545	188.879	187.344	191.798	180.156	13116	13289	10364	10221.95	12023	9759.99	ACTN4	actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Cell motility;Immune disease;Cancer: overview;Cellular community - eukaryotes;Cellular community - eukaryotes;Infectious disease: parasitic;Immune system;Cellular community - eukaryotes	ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04530//Tight junction;ko05146//Amoebiasis;ko04670//Leukocyte transendothelial migration;ko04520//Adherens junction	K05699;K05699;K05699;K05699;K05699;K05699;K05699;K05699;K05699	GO:0001725//stress fiber;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016604//nuclear body;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031093//platelet alpha granule lumen;GO:0031143//pseudopodium;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1990904//ribonucleoprotein complex	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001882//nucleoside binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0031490//chromatin DNA binding;GO:0042803//protein homodimerization activity;GO:0042974//retinoic acid receptor binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051015//actin filament binding	"GO:0001666//response to hypoxia;GO:0015031//protein transport;GO:0030036//actin cytoskeleton organization;GO:0030050//vesicle transport along actin filament;GO:0030335//positive regulation of cell migration;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048384//retinoic acid receptor signaling pathway;GO:0051272//positive regulation of cellular component movement;GO:0055001//muscle cell development;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903506//regulation of nucleic acid-templated transcription"	--
ENSG00000130413	11.51	9.273	8.632	7.392	10.091	7.589	482	400	249	230	261	264	STK33	serine/threonine kinase 33 [Source:HGNC Symbol;Acc:HGNC:14568]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0044773//mitotic DNA damage checkpoint signaling;GO:0046777//protein autophosphorylation	--
ENSG00000130414	39.657	42.618	42.714	50.749	42.189	42.495	1527	1592	1168	1368	1390	1209	NDUFA10	NADH:ubiquinone oxidoreductase subunit A10 [Source:HGNC Symbol;Acc:HGNC:7684]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954;K03954	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000130427	3.8	5.368	1.689	0.783	1.648	0.399	131	186	43	20	48	10	EPO	erythropoietin [Source:HGNC Symbol;Acc:HGNC:3415]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04066//HIF-1 signaling pathway	K05437;K05437;K05437;K05437;K05437;K05437	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0044297//cell body	GO:0005125//cytokine activity;GO:0005128//erythropoietin receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006953//acute-phase response;GO:0007165//signal transduction;GO:0007566//embryo implantation;GO:0007568//aging;GO:0007584//response to nutrient;GO:0008015//blood circulation;GO:0008284//positive regulation of cell population proliferation;GO:0009651//response to salt stress;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0010976//positive regulation of neuron projection development;GO:0018105//peptidyl-serine phosphorylation;GO:0030218//erythrocyte differentiation;GO:0032147//activation of protein kinase activity;GO:0032496//response to lipopolysaccharide;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0033189//response to vitamin A;GO:0033574//response to testosterone;GO:0038162//erythropoietin-mediated signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042541//hemoglobin biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0043249//erythrocyte maturation;GO:0043627//response to estrogen;GO:0045666//positive regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048678//response to axon injury;GO:0050896//response to stimulus;GO:0051602//response to electrical stimulus;GO:0055093//response to hyperoxia;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070555//response to interleukin-1;GO:0071474//cellular hyperosmotic response;GO:0071548//response to dexamethasone;GO:1901215//negative regulation of neuron death;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:1902251//negative regulation of erythrocyte apoptotic process;GO:2001258//negative regulation of cation channel activity"	--
ENSG00000130429	44.786	41.448	38.021	46.491	47.327	45.015	1401.21	1313.5	884.82	1084	1254.37	1030.89	ARPC1B	actin related protein 2/3 complex subunit 1B [Source:HGNC Symbol;Acc:HGNC:704]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0036284//tubulobulbar complex;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding	GO:0030833//regulation of actin filament polymerization;GO:0032355//response to estradiol;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0043627//response to estrogen	--
ENSG00000130433	1.349	3.102	1.201	1.675	2.1	1.854	68	129	46	55	76	67	CACNG6	calcium voltage-gated channel auxiliary subunit gamma 6 [Source:HGNC Symbol;Acc:HGNC:13625]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04871;K04871;K04871;K04871;K04871;K04871;K04871	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	--
ENSG00000130449	4.054	3.086	3.644	2.819	3.02	3.134	464	355	308	239	292	261	ZSWIM6	zinc finger SWIM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:29316]	-	-	-	-	GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007399//nervous system development;GO:0021773//striatal medium spiny neuron differentiation	--
ENSG00000130475	3.822	4.551	4.315	3.603	6.222	3.596	199	162	153	117	162	151	FCHO1	FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane	GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding	GO:0006897//endocytosis;GO:0048268//clathrin coat assembly;GO:0050852//T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0072583//clathrin-dependent endocytosis	--
ENSG00000130477	0.024	0.029	0.039	0.007	0	0.007	5	6	6	1	0	1	UNC13A	unc-13 homolog A [Source:HGNC Symbol;Acc:HGNC:23150]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15293	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098793//presynapse;GO:0098831//presynaptic active zone cytoplasmic component	GO:0005509//calcium ion binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0017075//syntaxin-1 binding;GO:0019992//diacylglycerol binding;GO:0046872//metal ion binding	"GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007528//neuromuscular junction development;GO:0016081//synaptic vesicle docking;GO:0016082//synaptic vesicle priming;GO:0016188//synaptic vesicle maturation;GO:0030154//cell differentiation;GO:0035249//synaptic transmission, glutamatergic;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0061789//dense core granule priming;GO:0099011//neuronal dense core vesicle exocytosis;GO:0099525//presynaptic dense core vesicle exocytosis;GO:1903861//positive regulation of dendrite extension"	--
ENSG00000130479	11.904	13.061	14.354	14.496	13.986	14.167	800	889	723	713	793	703	MAP1S	microtubule associated protein 1S [Source:HGNC Symbol;Acc:HGNC:15715]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0042802//identical protein binding;GO:0048487//beta-tubulin binding;GO:0051015//actin filament binding	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007420//brain development;GO:0010848//regulation of chromatin disassembly;GO:0016358//dendrite development;GO:0031114//regulation of microtubule depolymerization;GO:0047497//mitochondrion transport along microtubule;GO:0048812//neuron projection morphogenesis	--
ENSG00000130487	0	0	0	0	0.057	0	0	0	0	0	3	0	KLHDC7B	kelch domain containing 7B [Source:HGNC Symbol;Acc:HGNC:25145]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000130508	73.482	79.491	76.2	70.092	71.872	68.528	8856	9121	6402	5741	6895	5841	PXDN	peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	"GO:0004601//peroxidase activity;GO:0005152//interleukin-1 receptor antagonist activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0020037//heme binding;GO:0043237//laminin-1 binding;GO:0046872//metal ion binding"	GO:0001525//angiogenesis;GO:0001654//eye development;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0006955//immune response;GO:0006979//response to oxidative stress;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0042744//hydrogen peroxide catabolic process;GO:0051260//protein homooligomerization;GO:0070207//protein homotrimerization;GO:0070831//basement membrane assembly;GO:0071711//basement membrane organization;GO:0098869//cellular oxidant detoxification	--
ENSG00000130511	26.345	31.563	32.763	36.364	34.162	36.543	836	1001	719	812	798	746	SSBP4	single stranded DNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:15676]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000130513	0.377	0.16	0.285	0.434	0.285	0.939	11	4	6	8	6	17	GDF15	growth differentiation factor 15 [Source:HGNC Symbol;Acc:HGNC:30142]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05504	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0070700//BMP receptor binding	GO:0002023//reduction of food intake in response to dietary excess;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0043410//positive regulation of MAPK cascade;GO:0051897//positive regulation of protein kinase B signaling;GO:0060395//SMAD protein signal transduction;GO:0060400//negative regulation of growth hormone receptor signaling pathway;GO:1901741//positive regulation of myoblast fusion	--
ENSG00000130517	6.593	7.682	6.632	9.809	6.16	8.154	507	546	456	455	418	406	PGPEP1	pyroglutamyl-peptidase I [Source:HGNC Symbol;Acc:HGNC:13568]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016920//pyroglutamyl-peptidase activity	GO:0006508//proteolysis	--
ENSG00000130518	0.229	0.155	0.172	0.309	0.26	0.152	20	14	11	20	19	10	IQCN	IQ motif containing N [Source:HGNC Symbol;Acc:HGNC:29350]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000130520	49.433	50.19	53.141	60.133	54.578	51.811	1035	1086	849	949	983	809	LSM4	"LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12623;K12623	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0097526//spliceosomal tri-snRNP complex;GO:0120115//Lsm2-8 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0042731//PH domain binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0033962//P-body assembly"	--
ENSG00000130522	39.144	39.766	46.972	45.936	38.573	38.325	1242	1177	993	972	1049	900	JUND	"JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206]"	Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Development and regeneration;Endocrine system;Immune system	"ko04010//MAPK signaling pathway;ko04380//Osteoclast differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04657//IL-17 signaling pathway"	K04449;K04449;K04449;K04449	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0035976//transcription factor AP-1 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002076//osteoblast development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007568//aging;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009612//response to mechanical stimulus;GO:0014070//response to organic cyclic compound;GO:0032496//response to lipopolysaccharide;GO:0042127//regulation of cell population proliferation;GO:0043032//positive regulation of macrophage activation;GO:0043434//response to peptide hormone;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0071277//cellular response to calcium ion"	TF_bZIP
ENSG00000130528	0	0	0.028	0	0.028	0	0	0	1	0	1	0	HRC	histidine rich calcium binding protein [Source:HGNC Symbol;Acc:HGNC:5178]	Environmental Information Processing;Organismal Systems	Signal transduction;Circulatory system	ko04020//Calcium signaling pathway;ko04260//Cardiac muscle contraction	K23450;K23450	GO:0005788//endoplasmic reticulum lumen;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0051117//ATPase binding	GO:0002027//regulation of heart rate;GO:0006936//muscle contraction;GO:0008016//regulation of heart contraction;GO:0010460//positive regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0045823//positive regulation of heart contraction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055074//calcium ion homeostasis;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1901899//positive regulation of relaxation of cardiac muscle;GO:1903169//regulation of calcium ion transmembrane transport	--
ENSG00000130529	1.211	1.381	1.26	1.158	1.709	1.171	99	107	64	59	97	69	TRPM4	transient receptor potential cation channel subfamily M member 4 [Source:HGNC Symbol;Acc:HGNC:17993]	Organismal Systems	Endocrine system	ko04911//Insulin secretion	K04979	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034706//sodium channel complex;GO:0043025//neuronal cell body;GO:0044214//spanning component of plasma membrane;GO:0089717//spanning component of membrane	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005272//sodium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0099604//ligand-gated calcium channel activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002407//dendritic cell chemotaxis;GO:0002724//regulation of T cell cytokine production;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell population proliferation;GO:0010460//positive regulation of heart rate;GO:0016925//protein sumoylation;GO:0019722//calcium-mediated signaling;GO:0030502//negative regulation of bone mineralization;GO:0034220//ion transmembrane transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042310//vasoconstriction;GO:0042391//regulation of membrane potential;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045907//positive regulation of vasoconstriction;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0061337//cardiac conduction;GO:0070588//calcium ion transmembrane transport;GO:0071318//cellular response to ATP;GO:0086045//membrane depolarization during AV node cell action potential;GO:0086047//membrane depolarization during Purkinje myocyte cell action potential;GO:0086048//membrane depolarization during bundle of His cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098655//cation transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:1903949//positive regulation of atrial cardiac muscle cell action potential;GO:1904179//positive regulation of adipose tissue development;GO:1904199//positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization	--
ENSG00000130538	0	0	0	0	0	0	0	0	0	0	0	0	OR11H1	olfactory receptor family 11 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:15404]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000130540	0.226	0.31	0.178	0.436	0.334	0.363	12	16	7	15	15	14	SULT4A1	sulfotransferase family 4A member 1 [Source:HGNC Symbol;Acc:HGNC:14903]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0008150//biological_process;GO:0008202//steroid metabolic process;GO:0051923//sulfation;GO:0140059//dendrite arborization;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000130544	1.048	1.083	1.022	0.783	0.823	0.772	125	130	90	69	83	67	ZNF557	zinc finger protein 557 [Source:HGNC Symbol;Acc:HGNC:28632]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000130545	14.562	15.07	15.944	17.41	17.027	17.372	285	290	244	240	272	241	CRB3	crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237]	Human Diseases;Cellular Processes	Infectious disease: viral;Cellular community - eukaryotes	ko05165//Human papillomavirus infection;ko04530//Tight junction	K06090;K06090	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0035003//subapical complex;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019904//protein domain specific binding	GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0072659//protein localization to plasma membrane;GO:1901890//positive regulation of cell junction assembly	--
ENSG00000130558	0.127	0.222	0.079	0.131	0	0.303	2	3	3	5	0	4	OLFM1	olfactomedin 1 [Source:HGNC Symbol;Acc:HGNC:17187]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0044295//axonal growth cone;GO:0045202//synapse	GO:0005515//protein binding	GO:0003190//atrioventricular valve formation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0023041//neuronal signal transduction;GO:0030516//regulation of axon extension;GO:0043065//positive regulation of apoptotic process;GO:0060317//cardiac epithelial to mesenchymal transition	--
ENSG00000130559	10.477	10.173	9.36	8.267	9.727	8.842	1475	1430	967	861	1148	938	CAMSAP1	calmodulin regulated spectrin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:19946]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0036449//microtubule minus-end	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0030507//spectrin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0022604//regulation of cell morphogenesis;GO:0031113//regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development	--
ENSG00000130560	13.686	13.41	14.74	15.432	14.236	17.349	528	520	420	441	464	487	UBAC1	UBA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30221]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000130561	0	0	0	0	0	0	0	0	0	0	0	0	SAG	S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521]	Organismal Systems	Sensory system	ko04744//Phototransduction	K19627	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005829//cytosol;GO:0016020//membrane;GO:0042995//cell projection	GO:0001664//G protein-coupled receptor binding;GO:0002046//opsin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0051219//phosphoprotein binding	GO:0002031//G protein-coupled receptor internalization;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0043086//negative regulation of catalytic activity	--
ENSG00000130584	2.065	2.014	2.282	2.5	2.293	2.086	214.6	212.89	177.59	182.9	210.2	164.61	ZBTB46	zinc finger and BTB domain containing 46 [Source:HGNC Symbol;Acc:HGNC:16094]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030853//negative regulation of granulocyte differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0045656//negative regulation of monocyte differentiation;GO:2001199//negative regulation of dendritic cell differentiation;GO:2001200//positive regulation of dendritic cell differentiation	ZBTB
ENSG00000130589	1.282	1.271	1.233	1.171	1.107	1.101	266	265	189	180	194	159	HELZ2	helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0030374//nuclear receptor coactivator activity;GO:0046872//metal ion binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090501//RNA phosphodiester bond hydrolysis"	--
ENSG00000130590	3.741	4.357	3.522	3.526	5.339	5.244	169	171	101	118	177	134	SAMD10	sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129]	-	-	-	-	GO:0009898//cytoplasmic side of plasma membrane	GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway	--
ENSG00000130592	0.397	0.221	0.041	0.221	0.341	0.523	8	5	1	4	7	7	LSP1	lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05152//Tuberculosis;ko04625//C-type lectin receptor signaling pathway	K14957;K14957	GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0098761//cellular response to interleukin-7	--
ENSG00000130595	0.069	0.052	0.071	0	0.082	0.092	1	1	1	0	1	1	TNNT3	"troponin T3, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11950]"	-	-	-	-	GO:0005829//cytosol;GO:0005861//troponin complex	GO:0003779//actin binding;GO:0005523//tropomyosin binding;GO:0030172//troponin C binding;GO:0031013//troponin I binding;GO:0048306//calcium-dependent protein binding	GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0006942//regulation of striated muscle contraction;GO:0030049//muscle filament sliding;GO:0043462//regulation of ATPase activity;GO:0045214//sarcomere organization;GO:1903612//positive regulation of calcium-dependent ATPase activity	--
ENSG00000130598	0.284	0	0	0	0	0	4	0	0	0	0	0	TNNI2	"troponin I2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11946]"	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005861//troponin complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031014//troponin T binding	"GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060048//cardiac muscle contraction"	--
ENSG00000130635	29.478	36.145	17.14	16.08	23.135	13.754	5160	5972	1856	1909	3422	1619	COL5A1	collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005588//collagen type V trimer;GO:0005592//collagen type XI trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0043394//proteoglycan binding;GO:0046872//metal ion binding;GO:0048407//platelet-derived growth factor binding	"GO:0001568//blood vessel development;GO:0003007//heart morphogenesis;GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0032964//collagen biosynthetic process;GO:0035313//wound healing, spreading of epidermal cells;GO:0035989//tendon development;GO:0043588//skin development;GO:0045112//integrin biosynthetic process;GO:0048592//eye morphogenesis;GO:0051128//regulation of cellular component organization;GO:0097435//supramolecular fiber organization;GO:1903225//negative regulation of endodermal cell differentiation"	--
ENSG00000130638	51.038	50.654	48.496	47.61	49.29	53.048	3258	3090	2339	2362	2535	2341	ATXN10	ataxin 10 [Source:HGNC Symbol;Acc:HGNC:10549]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K19323	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0031175//neuron projection development;GO:0060271//cilium assembly	--
ENSG00000130640	28.319	28.217	29.744	31.629	30.062	25.756	1682	1654.24	1298	1372	1532.1	1107.13	TUBGCP2	tubulin gamma complex associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18599]	-	-	-	-	GO:0000922//spindle pole;GO:0000923//equatorial microtubule organizing center;GO:0000930//gamma-tubulin complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0008275//gamma-tubulin small complex;GO:0016020//membrane	GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0001764//neuron migration;GO:0007020//microtubule nucleation;GO:0007420//brain development;GO:0031122//cytoplasmic microtubule organization;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle;GO:0065003//protein-containing complex assembly	--
ENSG00000130643	0.964	0.636	1.113	0.894	0.632	1.232	20	17	16	15	16	23	CALY	calcyon neuron specific vesicular protein [Source:HGNC Symbol;Acc:HGNC:17938]	Organismal Systems	Nervous system	ko04728//Dopaminergic synapse	K15493	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0098843//postsynaptic endocytic zone;GO:0098978//glutamatergic synapse;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0032051//clathrin light chain binding;GO:0044877//protein-containing complex binding	GO:0006897//endocytosis;GO:0007212//dopamine receptor signaling pathway;GO:0008089//anterograde axonal transport;GO:0016197//endosomal transport;GO:0045807//positive regulation of endocytosis;GO:0048268//clathrin coat assembly;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:1905445//positive regulation of clathrin coat assembly;GO:2001019//positive regulation of retrograde axon cargo transport	--
ENSG00000130649	0.029	0	0.219	0.142	0.122	0.062	1	0	5	2	3	1	CYP2E1	cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Endocrine and metabolic disease;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Xenobiotics biodegradation and metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04932//Non-alcoholic fatty liver disease;ko04936//Alcoholic liver disease;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism;ko00140//Steroid hormone biosynthesis;ko00591//Linoleic acid metabolism	K07415;K07415;K07415;K07415;K07415;K07415;K07415;K07415;K07415;K07415;K07415	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0018601//4-nitrophenol 2-monooxygenase activity;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0030544//Hsp70 protein binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:0070330//aromatase activity;GO:0120319//long-chain fatty acid omega-1 hydroxylase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0002933//lipid hydroxylation;GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009617//response to bacterium;GO:0010193//response to ozone;GO:0010243//response to organonitrogen compound;GO:0016098//monoterpenoid metabolic process;GO:0018885//carbon tetrachloride metabolic process;GO:0018910//benzene metabolic process;GO:0018960//4-nitrophenol metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042197//halogenated hydrocarbon metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0045471//response to ethanol;GO:0046483//heterocycle metabolic process	--
ENSG00000130653	0.226	0.209	0.223	0.207	0.184	0.114	10	20	16	11	15	7	PNPLA7	patatin like phospholipase domain containing 7 [Source:HGNC Symbol;Acc:HGNC:24768]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K14676	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004622//lysophospholipase activity;GO:0016787//hydrolase activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0034638//phosphatidylcholine catabolic process	--
ENSG00000130656	0.242	0.301	0.327	0.082	0.215	0.249	4	5	4	1	3	3	HBZ	hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835]	-	-	-	-	GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000130669	54.65	58.96	68.307	84.687	81.028	76.712	2486	2536	2231	2516	2836	2360	PAK4	p21 (RAC1) activated kinase 4 [Source:HGNC Symbol;Acc:HGNC:16059]	Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Cell motility;Infectious disease: viral;Cellular community - eukaryotes;Development and regeneration;Cancer: overview;Immune system;Signal transduction;Cancer: specific types	ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04510//Focal adhesion;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma	K05734;K05734;K05734;K05734;K05734;K05734;K05734;K05734;K05734	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0005925//focal adhesion	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0045766//positive regulation of angiogenesis;GO:0060996//dendritic spine development;GO:0071407//cellular response to organic cyclic compound;GO:0098609//cell-cell adhesion;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000130675	0	0	0	0	0	0	0	0	0	0	0	0	MNX1	motor neuron and pancreas homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4979]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08025	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0031018//endocrine pancreas development;GO:0048812//neuron projection morphogenesis"	Homeobox
ENSG00000130684	3.388	3.141	3.599	3.617	4.566	3.091	263	248	205	208	295	174	ZNF337	zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000130695	2.78	2.744	2.791	2.772	2.831	2.477	226	222	168	157	189	143	CEP85	centrosomal protein 85 [Source:HGNC Symbol;Acc:HGNC:25309]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0007059//chromosome segregation;GO:0046602//regulation of mitotic centrosome separation	--
ENSG00000130699	2.991	3.181	3.015	2.576	3.17	3.623	273	262	209	186	261	222	TAF4	TATA-box binding protein associated factor 4 [Source:HGNC Symbol;Acc:HGNC:11537]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03022//Basal transcription factors	K03129;K03129	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0033276//transcription factor TFTC complex;GO:0071339//MLL1 complex	GO:0001046//core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0046982//protein heterodimerization activity	"GO:0001541//ovarian follicle development;GO:0006282//regulation of DNA repair;GO:0006351//transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000130700	0	0.018	0	0	0.065	0.051	0	1	0	0	3	2	GATA5	GATA binding protein 5 [Source:HGNC Symbol;Acc:HGNC:15802]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003180//aortic valve morphogenesis;GO:0003274//endocardial cushion fusion;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0035481//positive regulation of Notch signaling pathway involved in heart induction;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048738//cardiac muscle tissue development;GO:0060575//intestinal epithelial cell differentiation;GO:0062000//positive regulation of cardiac endothelial to mesenchymal transition;GO:0071773//cellular response to BMP stimulus;GO:1901228//positive regulation of transcription from RNA polymerase II promoter involved in heart development"	zf-GATA
ENSG00000130701	0	0	0	0	0	0	0	0	0	0	0	0	RBBP8NL	RBBP8 N-terminal like [Source:HGNC Symbol;Acc:HGNC:16144]	-	-	-	-	GO:0005615//extracellular space	GO:0005515//protein binding	-	--
ENSG00000130702	22.574	22.58	28.302	35.915	38.16	45.82	5271	5379	4823	6305	7586	7733	LAMA5	laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06240;K06240;K06240;K06240;K06240;K06240;K06240;K06240	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005610//laminin-5 complex;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0031594//neuromuscular junction;GO:0043083//synaptic cleft;GO:0043259//laminin-10 complex;GO:0043260//laminin-11 complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0001755//neural crest cell migration;GO:0001822//kidney development;GO:0001942//hair follicle development;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007411//axon guidance;GO:0007517//muscle organ development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016331//morphogenesis of embryonic epithelium;GO:0016477//cell migration;GO:0030155//regulation of cell adhesion;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045995//regulation of embryonic development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060271//cilium assembly;GO:0060445//branching involved in salivary gland morphogenesis;GO:0072659//protein localization to plasma membrane;GO:0098609//cell-cell adhesion	--
ENSG00000130703	14.131	15.146	14.92	16.784	11.193	16.348	805	824.04	622	539	590	620	OSBPL2	oxysterol binding protein like 2 [Source:HGNC Symbol;Acc:HGNC:15761]	-	-	-	-	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transfer activity;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0120020//cholesterol transfer activity"	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0007009//plasma membrane organization;GO:0015914//phospholipid transport;GO:0030301//cholesterol transport;GO:0032367//intracellular cholesterol transport;GO:0051289//protein homotetramerization;GO:0120009//intermembrane lipid transfer	--
ENSG00000130706	44.311	47.207	49.957	54.398	49.773	50.097	1288	1392	1098	1183	1232	1062	ADRM1	ADRM1 26S proteasome ubiquitin receptor [Source:HGNC Symbol;Acc:HGNC:15759]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K06691;K06691;K06691;K06691;K06691;K06691;K06691;K06691;K06691	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008541//proteasome regulatory particle, lid subcomplex"	GO:0002020//protease binding;GO:0005515//protein binding;GO:0043130//ubiquitin binding;GO:0061133//endopeptidase activator activity;GO:0070628//proteasome binding	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010950//positive regulation of endopeptidase activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043248//proteasome assembly	--
ENSG00000130707	53.878	60.677	48.137	50.052	46.432	40.125	1707	1940	1130	1174	1241	928	ASS1	argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko05418//Fluid shear stress and atherosclerosis;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis"	K01940;K01940;K01940;K01940;K01940	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0070062//extracellular exosome;GO:0070852//cell body fiber	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004055//argininosuccinate synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015643//toxic substance binding;GO:0016597//amino acid binding;GO:0016874//ligase activity;GO:0042802//identical protein binding	GO:0000050//urea cycle;GO:0000052//citrulline metabolic process;GO:0000053//argininosuccinate metabolic process;GO:0001822//kidney development;GO:0001889//liver development;GO:0006526//arginine biosynthetic process;GO:0006531//aspartate metabolic process;GO:0006953//acute-phase response;GO:0007494//midgut development;GO:0007568//aging;GO:0007584//response to nutrient;GO:0007623//circadian rhythm;GO:0008652//cellular amino acid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010043//response to zinc ion;GO:0010046//response to mycotoxin;GO:0014075//response to amine;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0043200//response to amino acid;GO:0043434//response to peptide hormone;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048545//response to steroid hormone;GO:0051384//response to glucocorticoid;GO:0060416//response to growth hormone;GO:0060539//diaphragm development;GO:0070542//response to fatty acid;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071242//cellular response to ammonium ion;GO:0071320//cellular response to cAMP;GO:0071346//cellular response to interferon-gamma;GO:0071356//cellular response to tumor necrosis factor;GO:0071377//cellular response to glucagon stimulus;GO:0071400//cellular response to oleic acid;GO:0071418//cellular response to amine stimulus;GO:0071499//cellular response to laminar fluid shear stress;GO:0071549//cellular response to dexamethasone stimulus;GO:1903038//negative regulation of leukocyte cell-cell adhesion	--
ENSG00000130711	0	0	0	0	0	0.12	0	0	0	0	0	3	PRDM12	PR/SET domain 12 [Source:HGNC Symbol;Acc:HGNC:13997]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1990226//histone methyltransferase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0019233//sensory perception of pain;GO:0022008//neurogenesis;GO:0031175//neuron projection development;GO:0032259//methylation;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051574//positive regulation of histone H3-K9 methylation;GO:1900111//positive regulation of histone H3-K9 dimethylation	zf-C2H2
ENSG00000130713	7.08	7.689	6.075	6.01	6.531	7.634	305	337	192	201	236	244	EXOSC2	exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K03679	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101019//nucleolar exosome (RNase complex)	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008312//7S RNA binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034475//U4 snRNA 3'-end processing;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0071028//nuclear mRNA surveillance;GO:0071034//CUT catabolic process;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0090304//nucleic acid metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000130714	16.066	23.491	18.182	22.201	21.358	18.345	976	1117	768	880	982	813	POMT1	protein O-mannosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:9202]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00515//Mannose type O-glycan biosynthesis	K00728;K00728;K00728	GO:0001669//acrosomal vesicle;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007275//multicellular organism development;GO:0030198//extracellular matrix organization;GO:0035269//protein O-linked mannosylation;GO:0097502//mannosylation;GO:1904100//positive regulation of protein O-linked glycosylation	--
ENSG00000130717	25.33	26.39	28.399	30.854	27.819	31.196	1135	1188	934	1025	1054	1017	UCK1	uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00876;K00876;K00876	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004849//uridine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019206//nucleoside kinase activity	GO:0016310//phosphorylation;GO:0044206//UMP salvage;GO:0044211//CTP salvage;GO:0071704//organic substance metabolic process	--
ENSG00000130720	6.657	7.832	5.391	16.259	16.37	11.655	430	482	258	752	880	503	FIBCD1	fibrinogen C domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25922]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008061//chitin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion	--
ENSG00000130724	85.363	88.892	86.851	83.277	77.732	81.034	1591	1664	1191	1149	1220	1102	CHMP2A	charged multivesicular body protein 2A [Source:HGNC Symbol;Acc:HGNC:30216]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12191;K12191	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000815//ESCRT III complex;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0031210//phosphatidylcholine binding	GO:0001778//plasma membrane repair;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0010324//membrane invagination;GO:0010458//exit from mitosis;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016032//viral process;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0031468//nuclear membrane reassembly;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045184//establishment of protein localization;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0051258//protein polymerization;GO:0051260//protein homooligomerization;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:0140014//mitotic nuclear division;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1903543//positive regulation of exosomal secretion;GO:1903723//negative regulation of centriole elongation;GO:1904903//ESCRT III complex disassembly	--
ENSG00000130725	34.841	36.81	37.719	48.84	37.38	43.688	798	852	637	799	734	725	UBE2M	ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10579	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019788//NEDD8 transferase activity	GO:0006464//cellular protein modification process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043525//positive regulation of neuron apoptotic process;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation	--
ENSG00000130726	97.545	103.904	99.974	114.702	99.251	91.845	4602	4939	3522	4034	4420	3407	TRIM28	tripartite motif containing 28 [Source:HGNC Symbol;Acc:HGNC:16384]	-	-	-	-	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0035851//Krueppel-associated box domain binding;GO:0046872//metal ion binding;GO:0070087//chromo shadow domain binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001837//epithelial to mesenchymal transition;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0007566//embryo implantation;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0042307//positive regulation of protein import into nucleus;GO:0043045//DNA methylation involved in embryo development;GO:0043388//positive regulation of DNA binding;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045739//positive regulation of DNA repair;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0060028//convergent extension involved in axis elongation;GO:0060669//embryonic placenta morphogenesis;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly;GO:1901536//negative regulation of DNA demethylation;GO:2000653//regulation of genetic imprinting"	--
ENSG00000130731	23.075	21.36	22.354	27.742	26.768	24.301	314	297	232	288	319	241	METTL26	methyltransferase like 26 [Source:HGNC Symbol;Acc:HGNC:14141]	-	-	-	-	-	-	-	--
ENSG00000130733	40.707	45.848	42.849	37.68	44.214	35.388	1278.8	1412.55	980.31	922.25	1168.19	862.57	YIPF2	Yip1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:28476]	-	-	-	-	GO:0000138//Golgi trans cisterna;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005802//trans-Golgi network;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031902//late endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0016192//vesicle-mediated transport	--
ENSG00000130734	6.642	5.902	7.44	7.799	7.87	11.334	220.02	212.71	206.17	205.64	244.33	252.78	ATG4D	autophagy related 4D cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:20789]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K08342;K08342	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000423//mitophagy;GO:0006508//proteolysis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0015031//protein transport;GO:0034497//protein localization to phagophore assembly site;GO:0051697//protein delipidation	--
ENSG00000130741	35.953	36.768	33.366	34.868	36.266	34.769	2578	2649.99	1767	1852	2197	1814	EIF2S3	eukaryotic translation initiation factor 2 subunit gamma [Source:HGNC Symbol;Acc:HGNC:3267]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0070062//extracellular exosome	"GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003743//translation initiation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008135//translation factor activity, RNA binding;GO:0016787//hydrolase activity;GO:0045296//cadherin binding"	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0045903//positive regulation of translational fidelity	--
ENSG00000130748	18.548	22.701	25.114	33.984	25.178	24.481	252	310	252	342	289	242	TMEM160	transmembrane protein 160 [Source:HGNC Symbol;Acc:HGNC:26042]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000130749	5.764	6.508	5.993	5.036	6.381	5.854	717	815	564	468	685	534	ZC3H4	zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:HGNC:17808]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0046872//metal ion binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000130751	6.996	5.745	7.652	13.482	10.751	10.359	218	179	170	303	271	246	NPAS1	neuronal PAS domain protein 1 [Source:HGNC Symbol;Acc:HGNC:7894]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001964//startle response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0042711//maternal behavior;GO:0045892//negative regulation of transcription, DNA-templated"	bHLH
ENSG00000130755	0	0.097	0	0	0.115	0	0	1	0	0	1	0	GMFG	glia maturation factor gamma [Source:HGNC Symbol;Acc:HGNC:4374]	-	-	-	-	GO:0005576//extracellular region;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003779//actin binding;GO:0004860//protein kinase inhibitor activity;GO:0008047//enzyme activator activity;GO:0008083//growth factor activity;GO:0071933//Arp2/3 complex binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity;GO:0071846//actin filament debranching;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000130758	3.853	4.129	5.025	4.148	4.902	5.136	300	294	252	227	283	291	MAP3K10	mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease	K04418;K04418	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003714//transcription corepressor activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007224//smoothened signaling pathway;GO:0007254//JNK cascade;GO:0008219//cell death;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043507//positive regulation of JUN kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation"	--
ENSG00000130762	0.914	1.02	1.051	2.118	2.308	2.325	52	52	42	59	94	99	ARHGEF16	Rho guanine nucleotide exchange factor 16 [Source:HGNC Symbol;Acc:HGNC:15515]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0030971//receptor tyrosine kinase binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding	GO:0050790//regulation of catalytic activity;GO:0060326//cell chemotaxis;GO:0090630//activation of GTPase activity;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000130764	11.944	11.682	13.046	12.085	12.612	12.026	1066	1048	860	799	951	781	LRRC47	leucine rich repeat containing 47 [Source:HGNC Symbol;Acc:HGNC:29207]	-	-	-	-	-	GO:0003723//RNA binding;GO:0004826//phenylalanine-tRNA ligase activity;GO:0005515//protein binding	GO:0006432//phenylalanyl-tRNA aminoacylation	--
ENSG00000130766	4.247	3.976	4.921	5.884	5.835	11.866	305	287	261	313	354	620	SESN2	sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746]	Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Aging;Cell growth and death	ko04150//mTOR signaling pathway;ko04211//Longevity regulating pathway;ko04115//p53 signaling pathway	K20394;K20394;K20394	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031588//nucleotide-activated protein kinase complex;GO:0031932//TORC2 complex;GO:1990316//Atg1/ULK1 kinase complex	"GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0032542//sulfiredoxin activity;GO:0044877//protein-containing complex binding;GO:0070728//leucine binding"	"GO:0001932//regulation of protein phosphorylation;GO:0006111//regulation of gluconeogenesis;GO:0006635//fatty acid beta-oxidation;GO:0007005//mitochondrion organization;GO:0009749//response to glucose;GO:0016239//positive regulation of macroautophagy;GO:0030308//negative regulation of cell growth;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032042//mitochondrial DNA metabolic process;GO:0032868//response to insulin;GO:0034198//cellular response to amino acid starvation;GO:0034599//cellular response to oxidative stress;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0043491//protein kinase B signaling;GO:0046323//glucose import;GO:0070328//triglyceride homeostasis;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:0072593//reactive oxygen species metabolic process;GO:0098869//cellular oxidant detoxification;GO:1900182//positive regulation of protein localization to nucleus;GO:1901031//regulation of response to reactive oxygen species;GO:1902010//negative regulation of translation in response to endoplasmic reticulum stress;GO:1904262//negative regulation of TORC1 signaling;GO:1904504//positive regulation of lipophagy;GO:1990253//cellular response to leucine starvation;GO:2000479//regulation of cAMP-dependent protein kinase activity"	--
ENSG00000130768	7.881	9.071	7.81	7.563	8.004	7.619	295	343	219	214	255	209	SMPDL3B	sphingomyelin phosphodiesterase acid like 3B [Source:HGNC Symbol;Acc:HGNC:21416]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	"GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding"	GO:0002376//immune system process;GO:0006629//lipid metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0006954//inflammatory response;GO:0008150//biological_process;GO:0008152//metabolic process;GO:0016042//lipid catabolic process;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0046466//membrane lipid catabolic process;GO:0050728//negative regulation of inflammatory response	--
ENSG00000130770	66.51	77.758	83.986	76.869	65.2	73.884	824	949	767	694	702	670	ATP5IF1	ATP synthase inhibitory factor subunit 1 [Source:HGNC Symbol;Acc:HGNC:871]	-	-	-	-	GO:0005739//mitochondrion;GO:0009986//cell surface;GO:0032991//protein-containing complex	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0042030//ATPase inhibitor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043532//angiostatin binding;GO:0051117//ATPase binding;GO:0140260//mitochondrial proton-transporting ATP synthase complex binding	GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006091//generation of precursor metabolites and energy;GO:0006783//heme biosynthetic process;GO:0030218//erythrocyte differentiation;GO:0032780//negative regulation of ATPase activity;GO:0051346//negative regulation of hydrolase activity;GO:0051882//mitochondrial depolarization;GO:0072593//reactive oxygen species metabolic process;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process;GO:1903214//regulation of protein targeting to mitochondrion;GO:1903578//regulation of ATP metabolic process;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	--
ENSG00000130772	6.749	6.425	10.198	8.156	9.189	8.328	162	156	182	154	191	147	MED18	mediator complex subunit 18 [Source:HGNC Symbol;Acc:HGNC:25944]	-	-	-	-	GO:0005634//nucleus;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006369//termination of RNA polymerase II transcription;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000130775	0.171	0.084	0.199	0.135	0.253	0.08	5	3	4	3	6	2	THEMIS2	thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0050852//T cell receptor signaling pathway;GO:0050864//regulation of B cell activation	--
ENSG00000130779	6.294	6.135	4.403	3.596	4.055	6.083	690	642	377	278	388	448	CLIP1	CAP-Gly domain containing linker protein 1 [Source:HGNC Symbol;Acc:HGNC:10461]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K10421	GO:0000776//kinetochore;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005882//intermediate filament;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0035371//microtubule plus-end;GO:0042995//cell projection;GO:0044354//macropinosome	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051010//microtubule plus-end binding	GO:0000278//mitotic cell cycle;GO:0001578//microtubule bundle formation;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization	--
ENSG00000130783	0	0	0	0	0	0	0	0	0	0	0	0	CCDC62	coiled-coil domain containing 62 [Source:HGNC Symbol;Acc:HGNC:30723]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity	GO:0001835//blastocyst hatching;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071392//cellular response to estradiol stimulus	--
ENSG00000130787	9.766	9.975	9.2	11.772	11.609	11.986	861	864	621	674	869	769	HIP1R	huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005938//cell cortex;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0032839//dendrite cytoplasm;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane	"GO:0003779//actin binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0017124//SH3 domain binding;GO:0030276//clathrin binding;GO:0032051//clathrin light chain binding;GO:0035091//phosphatidylinositol binding;GO:0035615//clathrin adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007015//actin filament organization;GO:0030100//regulation of endocytosis;GO:0030837//negative regulation of actin filament polymerization;GO:0032092//positive regulation of protein binding;GO:0032956//regulation of actin cytoskeleton organization;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0048268//clathrin coat assembly;GO:0050821//protein stabilization;GO:0055123//digestive system development;GO:0060453//regulation of gastric acid secretion;GO:0061024//membrane organization;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1905445//positive regulation of clathrin coat assembly;GO:2000369//regulation of clathrin-dependent endocytosis;GO:2000588//positive regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000130803	13.41	14.115	13.793	14.004	14.684	13.486	1128	1194	857	874	1043	825	ZNF317	zinc finger protein 317 [Source:HGNC Symbol;Acc:HGNC:13507]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000130810	7.288	8.657	7.533	9.154	6.98	9.118	297.5	343.88	219.46	238.97	261.11	273.68	PPAN	peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227]	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding;GO:0019843//rRNA binding	GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing	--
ENSG00000130811	110.893	109.697	113.402	126.922	114.758	100.23	2511	2519	1897	2144	2201	1655	EIF3G	eukaryotic translation initiation factor 3 subunit G [Source:HGNC Symbol;Acc:HGNC:3274]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0048471//perinuclear region of cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0075525//viral translational termination-reinitiation	--
ENSG00000130812	0.178	0.09	0	0.094	0.102	0	6.57	3.33	0	2.29	3.19	0	ANGPTL6	angiopoietin like 6 [Source:HGNC Symbol;Acc:HGNC:23140]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding	GO:0001525//angiogenesis;GO:0030154//cell differentiation	--
ENSG00000130813	10.831	9.59	11.928	14.19	12.834	14.273	428.43	372.67	348	381.71	428.81	414	SHFL	shiftless antiviral inhibitor of ribosomal frameshifting [Source:HGNC Symbol;Acc:HGNC:25649]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043022//ribosome binding;GO:1990825//sequence-specific mRNA binding	GO:0006449//regulation of translational termination;GO:0034340//response to type I interferon;GO:0034341//response to interferon-gamma;GO:0034342//response to type III interferon;GO:0035456//response to interferon-beta;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0075523//viral translational frameshifting;GO:2001125//negative regulation of translational frameshifting	--
ENSG00000130816	8.953	8.656	8.849	7.193	7.854	8.456	979	969	701	558	737	671	DNMT1	DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Amino acid metabolism	ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko00270//Cysteine and methionine metabolism	K00558;K00558;K00558	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005721//pericentric heterochromatin	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0009008//DNA-methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0007265//Ras protein signal transduction;GO:0010216//maintenance of DNA methylation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032259//methylation;GO:0032776//DNA methylation on cytosine;GO:0042127//regulation of cell population proliferation;GO:0043045//DNA methylation involved in embryo development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0071230//cellular response to amino acid stimulus;GO:0090116//C-5 methylation of cytosine;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly;GO:1903926//cellular response to bisphenol A;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905460//negative regulation of vascular associated smooth muscle cell apoptotic process;GO:1905931//negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching"	--
ENSG00000130818	4.693	4.214	2.996	3.637	2.62	3.022	438	421.29	205	228.03	238	214	ZNF426	zinc finger protein 426 [Source:HGNC Symbol;Acc:HGNC:20725]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000130821	47.987	47.892	44.715	53.896	52.185	44.004	3332	3377	2329	2789	3106	2313	SLC6A8	solute carrier family 6 member 8 [Source:HGNC Symbol;Acc:HGNC:11055]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005308//creatine transmembrane transporter activity;GO:0005309//creatine:sodium symporter activity;GO:0015293//symporter activity	GO:0006600//creatine metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006836//neurotransmitter transport;GO:0006936//muscle contraction;GO:0015881//creatine transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport	--
ENSG00000130822	4.564	4.446	5.697	7.493	4.996	6.431	95	90	90	121	93	93	PNCK	pregnancy up-regulated nonubiquitous CaM kinase [Source:HGNC Symbol;Acc:HGNC:13415]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation	--
ENSG00000130826	14.652	13.72	13.977	11.582	12.771	12.687	748	708	531	441	549	474	DKC1	dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11131	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0031429//box H/ACA snoRNP complex;GO:0072589//box H/ACA scaRNP complex;GO:0090661//box H/ACA telomerase RNP complex	GO:0003720//telomerase activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding	GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0000495//box H/ACA RNA 3'-end processing;GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0007004//telomere maintenance via telomerase;GO:0009451//RNA modification;GO:0031118//rRNA pseudouridine synthesis;GO:0031120//snRNA pseudouridine synthesis;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0033979//box H/ACA RNA metabolic process;GO:0042254//ribosome biogenesis;GO:0051973//positive regulation of telomerase activity;GO:0090666//scaRNA localization to Cajal body;GO:0090669//telomerase RNA stabilization;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904872//regulation of telomerase RNA localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000130827	2.316	2.331	2.333	2.14	2.118	2.112	523	529	389	357.82	404	347	PLXNA3	plexin A3 [Source:HGNC Symbol;Acc:HGNC:9101]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06820	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity	GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0021612//facial nerve structural organization;GO:0021637//trigeminal nerve structural organization;GO:0021766//hippocampus development;GO:0021785//branchiomotor neuron axon guidance;GO:0021860//pyramidal neuron development;GO:0030334//regulation of cell migration;GO:0043087//regulation of GTPase activity;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050772//positive regulation of axonogenesis;GO:0050919//negative chemotaxis;GO:0051495//positive regulation of cytoskeleton organization;GO:0071526//semaphorin-plexin signaling pathway;GO:0097485//neuron projection guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1990138//neuron projection extension	--
ENSG00000130829	0	0	0	0	0	0.029	0	0	0	0	0	1	DUSP9	dual specificity phosphatase 9 [Source:HGNC Symbol;Acc:HGNC:3076]	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells	K18498;K18498	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0006470//protein dephosphorylation;GO:0007254//JNK cascade;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0060420//regulation of heart growth;GO:0070371//ERK1 and ERK2 cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000130830	3.059	3.736	3.937	3.504	3.545	3.954	118	147	121	108	125	115	MPP1	membrane palmitoylated protein 1 [Source:HGNC Symbol;Acc:HGNC:7219]	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0032420//stereocilium;GO:0034451//centriolar satellite;GO:0042995//cell projection	GO:0004385//guanylate kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process;GO:0090022//regulation of neutrophil chemotaxis	--
ENSG00000130844	6.061	4.636	5.431	6.11	5.99	5.887	409	334	253	251	287	263	ZNF331	zinc finger protein 331 [Source:HGNC Symbol;Acc:HGNC:15489]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000130856	2.12	1.802	2.242	1.859	1.993	2.162	375	319	278	246	303	251	ZNF236	zinc finger protein 236 [Source:HGNC Symbol;Acc:HGNC:13028]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0071333//cellular response to glucose stimulus	zf-C2H2
ENSG00000130876	0	0.099	0	0.134	0.381	0.298	0	4	0	4	13	8	SLC7A10	solute carrier family 7 member 10 [Source:HGNC Symbol;Acc:HGNC:11058]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015825//L-serine transport;GO:0042941//D-alanine transport;GO:0042942//D-serine transport;GO:0055085//transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000130881	11.108	12.6	12.274	15.959	15.131	13.618	935	1066	763	995	1076	834	LRP3	LDL receptor related protein 3 [Source:HGNC Symbol;Acc:HGNC:6695]	-	-	-	-	GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0150104//transport across blood-brain barrier	--
ENSG00000130921	8.303	8.469	7.126	7.155	5.31	7.426	333.7	336.6	220.83	207.77	175.84	213.5	MTRFR	mitochondrial translation release factor in rescue [Source:HGNC Symbol;Acc:HGNC:26784]	-	-	-	-	GO:0005739//mitochondrion	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003747//translation release factor activity;GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding	GO:0006412//translation;GO:0006415//translational termination;GO:0072344//rescue of stalled ribosome	--
ENSG00000130935	15.437	12.724	14.69	11.12	11.837	15.293	872	749	640	464	579	616	NOL11	nucleolar protein 11 [Source:HGNC Symbol;Acc:HGNC:24557]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0034455//t-UTP complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	--
ENSG00000130939	30.456	28.004	26.946	25.375	26.11	26.761	3309	3078	2183	2061	2414	2118	UBE4B	ubiquitination factor E4B [Source:HGNC Symbol;Acc:HGNC:12500]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K10597;K10597	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0034450//ubiquitin-ubiquitin ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0009411//response to UV;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000130940	0.243	0.229	0.183	0.269	0.539	0.286	25	22	20	21	45	23	CASZ1	castor zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:26002]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0045664//regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Others
ENSG00000130943	0.019	0.019	0.025	0.034	0.007	0.017	3	3	3	4	1	2	PKDREJ	polycystin family receptor for egg jelly [Source:HGNC Symbol;Acc:HGNC:9015]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006811//ion transport;GO:0007340//acrosome reaction;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport	--
ENSG00000130948	3.605	4.124	4.458	1.937	1.816	2.506	84.6	100.29	78.39	34	35.49	41.76	HSD17B3	hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K10207;K10207	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0102196//cortisol dehydrogenase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0030539//male genitalia development;GO:0061370//testosterone biosynthetic process	--
ENSG00000130950	0	0.037	0.077	0.076	0.089	0.119	0	2	3	3	4	4.61	NUTM2F	NUT family member 2F [Source:HGNC Symbol;Acc:HGNC:23450]	-	-	-	-	-	-	-	--
ENSG00000130956	14.78	14.867	15.363	17.775	18.962	21.289	812.73	821.68	622.86	724	880.88	850.81	HABP4	hyaluronan binding protein 4 [Source:HGNC Symbol;Acc:HGNC:17062]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0015030//Cajal body;GO:0016528//sarcoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0030017//sarcomere;GO:0031965//nuclear membrane;GO:0097504//Gemini of coiled bodies	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0032183//SUMO binding	GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0008380//RNA splicing;GO:0030578//PML body organization;GO:0033120//positive regulation of RNA splicing;GO:0043392//negative regulation of DNA binding;GO:0045948//positive regulation of translational initiation;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000130957	7.542	7.683	6.792	5.456	6.023	5.456	209	214	139	112	141	110	FBP2	fructose-bisphosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3607]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Signal transduction;Global and overview maps;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K03841;K03841;K03841;K03841;K03841;K03841;K03841;K03841	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0005986//sucrose biosynthetic process;GO:0006000//fructose metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006094//gluconeogenesis;GO:0008152//metabolic process;GO:0016311//dephosphorylation;GO:0030388//fructose 1,6-bisphosphate metabolic process"	--
ENSG00000130958	9.14	8.662	9.405	9.422	9.767	8.565	294.01	285.8	226.47	225	264.34	207.56	SLC35D2	solute carrier family 35 member D2 [Source:HGNC Symbol;Acc:HGNC:20799]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005338//nucleotide-sugar transmembrane transporter activity;GO:0005461//UDP-glucuronic acid transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463//UDP-N-acetylgalactosamine transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:0008150//biological_process;GO:0008643//carbohydrate transport;GO:0015787//UDP-glucuronic acid transmembrane transport;GO:0015789//UDP-N-acetylgalactosamine transmembrane transport;GO:0015931//nucleobase-containing compound transport;GO:0018146//keratan sulfate biosynthetic process;GO:0055085//transmembrane transport;GO:1901264//carbohydrate derivative transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000130962	4.629	4.379	3.931	3.979	3.599	5.291	423	393.94	265	269	280	345	PRRG1	proline rich and Gla domain 1 [Source:HGNC Symbol;Acc:HGNC:9469]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000130985	134.247	138.972	149.225	150.744	150.962	131.64	9722	10167	8051	8091	9307	7005	UBA1	ubiquitin like modifier activating enzyme 1 [Source:HGNC Symbol;Acc:HGNC:12469]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K03178;K03178;K03178	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0030057//desmosome;GO:0030867//rough endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004839//ubiquitin activating enzyme activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016874//ligase activity	GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation	--
ENSG00000130988	13.787	14.064	13.259	9.583	10.593	11.629	486	503	350	251	321	302	RGN	regucalcin [Source:HGNC Symbol;Acc:HGNC:9989]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00030//Pentose phosphate pathway;ko00053//Ascorbate and aldarate metabolism	K01053;K01053;K01053;K01053	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004341//gluconolactonase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0001889//liver development;GO:0001933//negative regulation of protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006874//cellular calcium ion homeostasis;GO:0007283//spermatogenesis;GO:0007568//aging;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010907//positive regulation of glucose metabolic process;GO:0010922//positive regulation of phosphatase activity;GO:0019853//L-ascorbic acid biosynthetic process;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0032781//positive regulation of ATPase activity;GO:0034260//negative regulation of GTPase activity;GO:0043066//negative regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050848//regulation of calcium-mediated signaling;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0097421//liver regeneration;GO:1901318//negative regulation of flagellated sperm motility;GO:1901671//positive regulation of superoxide dismutase activity;GO:1901896//positive regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1902679//negative regulation of RNA biosynthetic process;GO:1903011//negative regulation of bone development;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process;GO:1903611//negative regulation of calcium-dependent ATPase activity;GO:1903625//negative regulation of DNA catabolic process;GO:1903629//positive regulation of dUTP diphosphatase activity;GO:1903634//negative regulation of leucine-tRNA ligase activity;GO:2000279//negative regulation of DNA biosynthetic process	--
ENSG00000130997	0.434	0.124	0.229	0.045	0.195	0.184	27	7.5	11.2	2	9.91	8.05	POLN	DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K16618	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0030332//cyclin binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0019985//translesion synthesis;GO:0036297//interstrand cross-link repair;GO:0071897//DNA biosynthetic process	--
ENSG00000131013	8.743	8.217	7.068	6.022	6.802	6.613	445	424	268	229	295	247	PPIL4	peptidylprolyl isomerase like 4 [Source:HGNC Symbol;Acc:HGNC:15702]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:1901407//regulation of phosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000131015	1.625	1.401	1.125	0.829	0.641	1.539	45	39	23	17	15	31	ULBP2	UL16 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14894]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07986	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0002376//immune system process;GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000131016	3.262	2.859	3.032	1.711	1.262	1.273	465	406	318	182	165	140	AKAP12	A-kinase anchoring protein 12 [Source:HGNC Symbol;Acc:HGNC:370]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0043025//neuronal cell body;GO:0098685//Schaffer collateral - CA1 synapse	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008179//adenylate cyclase binding;GO:0051018//protein kinase A binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0010738//regulation of protein kinase A signaling;GO:0010739//positive regulation of protein kinase A signaling;GO:0032496//response to lipopolysaccharide;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035733//hepatic stellate cell activation;GO:0043116//negative regulation of vascular permeability;GO:0050804//modulation of chemical synaptic transmission;GO:0051602//response to electrical stimulus;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0061870//positive regulation of hepatic stellate cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090036//regulation of protein kinase C signaling;GO:1900143//positive regulation of oligodendrocyte apoptotic process	--
ENSG00000131018	9.291	6.956	6.689	3.483	4.43	4.417	2025	1407	846	468	734	548	SYNE1	spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030017//sarcomere;GO:0031965//nuclear membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0045211//postsynaptic membrane	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0051015//actin filament binding;GO:0140444//cytoskeleton-nuclear membrane anchor activity	GO:0006997//nucleus organization;GO:0007030//Golgi organization;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042692//muscle cell differentiation;GO:0090292//nuclear matrix anchoring at nuclear membrane	--
ENSG00000131019	1.209	1.405	1.551	0.921	1.211	1.187	78	85.42	53	44	66	51	ULBP3	UL16 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:14895]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07986	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0002376//immune system process;GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000131023	6.423	4.657	5.127	3.863	4.502	4.293	894	664	508	395	503	477	LATS1	large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K08791;K08791	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030331//estrogen receptor binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000819//sister chromatid segregation;GO:0001827//inner cell mass cell fate commitment;GO:0001828//inner cell mass cellular morphogenesis;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0009755//hormone-mediated signaling pathway;GO:0016310//phosphorylation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0030216//keratinocyte differentiation;GO:0030833//regulation of actin filament polymerization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034613//cellular protein localization;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043254//regulation of protein-containing complex assembly;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0046620//regulation of organ growth;GO:0051220//cytoplasmic sequestering of protein;GO:0051301//cell division;GO:0060644//mammary gland epithelial cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900181//negative regulation of protein localization to nucleus;GO:2000058//regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000131037	0.816	0.615	0.948	0.962	0.523	0.928	32	27	32	28	21	29	EPS8L1	EPS8 like 1 [Source:HGNC Symbol;Acc:HGNC:21295]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0042608//T cell receptor binding;GO:0045296//cadherin binding	GO:0007266//Rho protein signal transduction;GO:0016310//phosphorylation;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000131042	0	0	0	0	0	0	0	0	0	0	0	0	LILRB2	leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0023025//MHC class Ib protein complex binding;GO:0023029//MHC class Ib protein binding;GO:0032396//inhibitory MHC class I receptor activity;GO:0042288//MHC class I protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0050839//cell adhesion molecule binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002578//negative regulation of antigen processing and presentation;GO:0002645//positive regulation of tolerance induction;GO:0002666//positive regulation of T cell tolerance induction;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007611//learning or memory;GO:0019221//cytokine-mediated signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0034113//heterotypic cell-cell adhesion;GO:0035307//positive regulation of protein dephosphorylation;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0051248//negative regulation of protein metabolic process;GO:0051926//negative regulation of calcium ion transport;GO:0071222//cellular response to lipopolysaccharide;GO:0140105//interleukin-10-mediated signaling pathway;GO:1900271//regulation of long-term synaptic potentiation;GO:1900454//positive regulation of long-term synaptic depression;GO:1905875//negative regulation of postsynaptic density organization;GO:2000524//negative regulation of T cell costimulation;GO:2001198//regulation of dendritic cell differentiation	--
ENSG00000131043	20.807	21.585	24.22	29.215	23.059	28.383	1053	1100	910	1088	989	1055	AAR2	AAR2 splicing factor [Source:HGNC Symbol;Acc:HGNC:15886]	-	-	-	-	GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP	-	GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000131044	0.66	0.594	0.4	0.551	0.398	0.553	28.17	25.19	12.08	19.06	12.06	17.06	TTLL9	tubulin tyrosine ligase like 9 [Source:HGNC Symbol;Acc:HGNC:16118]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation;GO:0030317//flagellated sperm motility	--
ENSG00000131050	0	0	0.125	0	0	0.064	0	0	2	0	0	1	BPIFA2	BPI fold containing family A member 2 [Source:HGNC Symbol;Acc:HGNC:16203]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0042742//defense response to bacterium	--
ENSG00000131051	37.363	31.909	35.074	26.156	30.409	37.304	1797	1584	1203	832	1150	1263	RBM39	RNA binding motif protein 39 [Source:HGNC Symbol;Acc:HGNC:15923]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0050733//RS domain binding	"GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000131055	0.865	0.287	0.293	0.389	0.171	0.099	12	4	3	4	2	1	COX4I2	cytochrome c oxidase subunit 4I2 [Source:HGNC Symbol;Acc:HGNC:16232]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004129//cytochrome-c oxidase activity;GO:0016491//oxidoreductase activity	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000131059	0	0	0	0	0	0	0	0	0	0	0	0	BPIFA3	BPI fold containing family A member 3 [Source:HGNC Symbol;Acc:HGNC:16204]	-	-	-	-	GO:0005576//extracellular region	GO:0008289//lipid binding	-	--
ENSG00000131061	0.62	0.603	1.025	0.809	0.869	1.213	43	46	53	42	55	67	ZNF341	zinc finger protein 341 [Source:HGNC Symbol;Acc:HGNC:15992]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000131067	5.241	4.772	4.33	4.765	5.235	4.647	237	225	157	176	242	185	GGT7	gamma-glutamyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4259]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K00681;K00681;K00681	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0036374//glutathione hydrolase activity;GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0103068//leukotriene C4 gamma-glutamyl transferase activity	GO:0006508//proteolysis;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006751//glutathione catabolic process;GO:1901750//leukotriene D4 biosynthetic process;GO:1902883//negative regulation of response to oxidative stress	--
ENSG00000131068	0	0	0	0	0	0	0	0	0	0	0	0	DEFB118	defensin beta 118 [Source:HGNC Symbol;Acc:HGNC:16196]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0007160//cell-matrix adhesion;GO:0007283//spermatogenesis;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0051673//membrane disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000131069	18.374	21.758	24.564	23.378	19.992	22.573	897	951	728	776	741	716	ACSS2	acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K01895;K01895;K01895;K01895;K01895;K01895	GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003987//acetate-CoA ligase activity;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016874//ligase activity;GO:0050218//propionate-CoA ligase activity	GO:0006069//ethanol oxidation;GO:0006629//lipid metabolic process;GO:0008610//lipid biosynthetic process;GO:0019427//acetyl-CoA biosynthetic process from acetate	--
ENSG00000131080	0.028	0.014	0	0	0.033	0	2	1	0	0	2	0	EDA2R	ectodysplasin A2 receptor [Source:HGNC Symbol;Acc:HGNC:17756]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway	K05163;K05163	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0008544//epidermis development;GO:0010668//ectodermal cell differentiation;GO:0030154//cell differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046330//positive regulation of JNK cascade;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000131089	13.843	12.794	13.056	10.063	12.695	12.955	1016	946	771.04	607	811.01	748	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9 [Source:HGNC Symbol;Acc:HGNC:14561]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045202//synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000131094	1.831	1.947	2.693	2.089	1.981	1.606	58	62	63	49	53	37	C1QL1	complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0043083//synaptic cleft;GO:0044301//climbing fiber;GO:0098793//presynapse	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007626//locomotory behavior;GO:0016322//neuron remodeling;GO:0061743//motor learning;GO:0099558//maintenance of synapse structure	--
ENSG00000131095	0.49	0.097	0.359	0.612	0.298	0.4	34.43	6	23.48	16	16	19.99	GFAP	glial fibrillary acidic protein [Source:HGNC Symbol;Acc:HGNC:4235]	Environmental Information Processing	Signal transduction	ko04630//JAK-STAT signaling pathway	K05640	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0042995//cell projection;GO:0044297//cell body;GO:0045111//intermediate filament cytoskeleton;GO:0097386//glial cell projection;GO:0097449//astrocyte projection;GO:0097450//astrocyte end-foot;GO:0098574//cytoplasmic side of lysosomal membrane	GO:0005178//integrin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042802//identical protein binding	GO:0006886//intracellular protein transport;GO:0009611//response to wounding;GO:0010467//gene expression;GO:0010625//positive regulation of Schwann cell proliferation;GO:0010977//negative regulation of neuron projection development;GO:0014002//astrocyte development;GO:0030198//extracellular matrix organization;GO:0031102//neuron projection regeneration;GO:0043254//regulation of protein-containing complex assembly;GO:0045103//intermediate filament-based process;GO:0045109//intermediate filament organization;GO:0051580//regulation of neurotransmitter uptake;GO:0060020//Bergmann glial cell differentiation;GO:0060252//positive regulation of glial cell proliferation;GO:0060291//long-term synaptic potentiation;GO:0070779//D-aspartate import across plasma membrane;GO:1904714//regulation of chaperone-mediated autophagy	--
ENSG00000131096	0	0	0	0	0	0	0	0	0	0	0	0	PYY	peptide YY [Source:HGNC Symbol;Acc:HGNC:9748]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05233	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0031841//neuropeptide Y receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0060575//intestinal epithelial cell differentiation	--
ENSG00000131097	0	0	0	0	0	0	0	0	0	0	0	0	HIGD1B	HIG1 hypoxia inducible domain family member 1B [Source:HGNC Symbol;Acc:HGNC:24318]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0097250//mitochondrial respirasome assembly	--
ENSG00000131100	75.357	75.861	76.089	71.847	66.357	69.04	2064	2088	1544	1466	1533	1369	ATP6V1E1	ATPase H+ transporting V1 subunit E1 [Source:HGNC Symbol;Acc:HGNC:857]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0006811//ion transport;GO:0016241//regulation of macroautophagy;GO:1902600//proton transmembrane transport	--
ENSG00000131115	5.873	5.101	4.723	3.639	4.797	5.364	308.56	290.44	189.33	168.95	229.6	226	ZNF227	zinc finger protein 227 [Source:HGNC Symbol;Acc:HGNC:13020]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000131116	29.745	29.474	31.863	38.623	32.391	32.394	710.98	710.98	564.98	683.99	654	565	ZNF428	zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000131126	0	0	0	0	0	0	0	0	0	0	0	0	TEX101	testis expressed 101 [Source:HGNC Symbol;Acc:HGNC:30722]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding	GO:0007339//binding of sperm to zona pellucida;GO:0009566//fertilization;GO:0030317//flagellated sperm motility;GO:1901317//regulation of flagellated sperm motility	--
ENSG00000131127	1.106	0.709	0.97	0.656	0.834	0.842	289	180	126	127	146	155	ZNF141	zinc finger protein 141 [Source:HGNC Symbol;Acc:HGNC:12926]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0035108//limb morphogenesis"	zf-C2H2
ENSG00000131142	0	0.252	0	0.087	0.06	0.215	0	5	0	1	1	3	CCL25	C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04672//Intestinal immune network for IgA production;ko04061//Viral protein interaction with cytokine and cytokine receptor	K13072;K13072;K13072;K13072	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031735//CCR10 chemokine receptor binding;GO:0042379//chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0001954//positive regulation of cell-matrix adhesion;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016477//cell migration;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:1903237//negative regulation of leukocyte tethering or rolling	--
ENSG00000131143	229.349	223.634	236.411	274.732	228.965	246.683	3624	3552	2764	3224	3060	2840	COX4I1	cytochrome c oxidase subunit 4I1 [Source:HGNC Symbol;Acc:HGNC:2265]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263;K02263	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000131148	9.775	10.354	11.546	10.577	11.749	12.33	398	417	347	311	404	365	EMC8	ER membrane protein complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:7864]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000131149	6.737	6.976	6.048	5.587	6.887	5.718	937	940	624	596	800	590	GSE1	Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000131152	0.078	0	0.599	0	0.221	0	1.54	0	8.75	0	3.69	0	C16orf95	novel protein	-	-	-	-	-	-	-	--
ENSG00000131153	0.404	1.095	0.422	0.52	0.413	0.328	22	60	17	21	19	13	GINS2	GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575]	-	-	-	-	GO:0000811//GINS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031981//nuclear lumen;GO:0071162//CMG complex	GO:0005515//protein binding	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0044238//primary metabolic process;GO:0071704//organic substance metabolic process;GO:1900264//positive regulation of DNA-directed DNA polymerase activity;GO:1903934//positive regulation of DNA primase activity	--
ENSG00000131165	28.7	33.061	32.766	35.727	37.102	35.247	1407	1622	1178	1292	1494	1256	CHMP1A	charged multivesicular body protein 1A [Source:HGNC Symbol;Acc:HGNC:8740]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12197;K12197	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000794//condensed nuclear chromosome;GO:0000815//ESCRT III complex;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005771//multivesicular body;GO:0005815//microtubule organizing center;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030496//midbody;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0001778//plasma membrane repair;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0007080//mitotic metaphase plate congression;GO:0010629//negative regulation of gene expression;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016032//viral process;GO:0016192//vesicle-mediated transport;GO:0031468//nuclear membrane reassembly;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0051301//cell division;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:0140014//mitotic nuclear division;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904903//ESCRT III complex disassembly	--
ENSG00000131171	96.805	83.857	86.148	76.081	71.784	95.221	3542	3084	2328	2062	2219	2535	SH3BGRL	SH3 domain binding glutamate rich protein like [Source:HGNC Symbol;Acc:HGNC:10823]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0017124//SH3 domain binding	-	--
ENSG00000131174	16.451	17.323	15.811	16.888	13.055	22.227	705	686	484	500	460	591	COX7B	cytochrome c oxidase subunit 7B [Source:HGNC Symbol;Acc:HGNC:2291]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0007417//central nervous system development;GO:0022900//electron transport chain;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000131183	0	0	0	0	0	0	0	0	0	0	0	0	SLC34A1	solute carrier family 34 member 1 [Source:HGNC Symbol;Acc:HGNC:11019]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	"ko04928//Parathyroid hormone synthesis, secretion and action;ko04978//Mineral absorption"	K14683;K14683	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016607//nuclear speck;GO:0031226//intrinsic component of plasma membrane;GO:0031526//brush border membrane;GO:0031982//vesicle;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle	GO:0005436//sodium:phosphate symporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0001503//ossification;GO:0001822//kidney development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0007584//response to nutrient;GO:0009100//glycoprotein metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010288//response to lead ion;GO:0030643//cellular phosphate ion homeostasis;GO:0032026//response to magnesium ion;GO:0032355//response to estradiol;GO:0033189//response to vitamin A;GO:0035435//phosphate ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0035864//response to potassium ion;GO:0042431//indole metabolic process;GO:0043434//response to peptide hormone;GO:0044267//cellular protein metabolic process;GO:0044341//sodium-dependent phosphate transport;GO:0045838//positive regulation of membrane potential;GO:0046686//response to cadmium ion;GO:0046689//response to mercury ion;GO:0055062//phosphate ion homeostasis;GO:0060416//response to growth hormone;GO:0071107//response to parathyroid hormone;GO:0071248//cellular response to metal ion;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0072350//tricarboxylic acid metabolic process;GO:0072734//cellular response to staurosporine;GO:0097066//response to thyroid hormone;GO:0097187//dentinogenesis;GO:0098719//sodium ion import across plasma membrane;GO:1901128//gentamycin metabolic process;GO:1901652//response to peptide;GO:1901684//arsenate ion transmembrane transport;GO:2000120//positive regulation of sodium-dependent phosphate transport;GO:2000187//positive regulation of phosphate transmembrane transport	--
ENSG00000131187	0.26	0.424	0.064	0.16	0.252	0.065	11	18	2	5	9	2	F12	coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01328	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0051787//misfolded protein binding	"GO:0002353//plasma kallikrein-kinin cascade;GO:0002542//Factor XII activation;GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis;GO:0010756//positive regulation of plasminogen activation;GO:0016485//protein processing;GO:0016540//protein autoprocessing;GO:0030194//positive regulation of blood coagulation;GO:0031638//zymogen activation;GO:0042730//fibrinolysis;GO:0045087//innate immune response;GO:0051788//response to misfolded protein;GO:0051919//positive regulation of fibrinolysis"	--
ENSG00000131188	5.87	5.528	6.949	6.082	6.467	4.996	163	154	143	126	155	100	PRR7	"proline rich 7, synaptic [Source:HGNC Symbol;Acc:HGNC:28130]"	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0005515//protein binding;GO:0036041//long-chain fatty acid binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044877//protein-containing complex binding;GO:1990782//protein tyrosine kinase binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0010942//positive regulation of cell death;GO:0031397//negative regulation of protein ubiquitination;GO:0033077//T cell differentiation in thymus;GO:0043065//positive regulation of apoptotic process;GO:0046632//alpha-beta T cell differentiation;GO:0099527//postsynapse to nucleus signaling pathway;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000131196	6.033	7.236	6.857	5.653	5.946	4.888	513	610	427	340	445	318	NFATC1	nuclear factor of activated T cells 1 [Source:HGNC Symbol;Acc:HGNC:7775]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Signal transduction;Signal transduction;Infectious disease: viral;Cell growth and death;Endocrine system;Immune system;Development and regeneration;Immune system;Immune system;Immune system;Endocrine and metabolic disease;Immune system;Cancer: overview;Immune disease	ko04010//MAPK signaling pathway;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321//Inflammatory bowel disease	K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446;K04446	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0030178//negative regulation of Wnt signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1905064//negative regulation of vascular associated smooth muscle cell differentiation"	RHD
ENSG00000131203	0	0	0	0.085	0.033	0	0	0	0	2	1	0	IDO1	"indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059]"	Metabolism;Human Diseases;Metabolism	Global and overview maps;Infectious disease: parasitic;Amino acid metabolism	ko01100//Metabolic pathways;ko05143//African trypanosomiasis;ko00380//Tryptophan metabolism	K00463;K00463;K00463	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030485//smooth muscle contractile fiber;GO:0032421//stereocilium bundle	"GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0002376//immune system process;GO:0002666//positive regulation of T cell tolerance induction;GO:0002678//positive regulation of chronic inflammatory response;GO:0002830//positive regulation of type 2 immune response;GO:0006569//tryptophan catabolic process;GO:0006954//inflammatory response;GO:0007565//female pregnancy;GO:0019441//tryptophan catabolic process to kynurenine;GO:0022900//electron transport chain;GO:0032496//response to lipopolysaccharide;GO:0032693//negative regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0033555//multicellular organismal response to stress;GO:0034276//kynurenic acid biosynthetic process;GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0036269//swimming behavior;GO:0042130//negative regulation of T cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0046007//negative regulation of activated T cell proliferation;GO:0070233//negative regulation of T cell apoptotic process;GO:0070234//positive regulation of T cell apoptotic process	--
ENSG00000131233	0.025	0.076	0.034	0.068	0.12	0.035	1	3	1	2	4	1	GJA9	gap junction protein alpha 9 [Source:HGNC Symbol;Acc:HGNC:19155]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0055085//transmembrane transport	--
ENSG00000131236	73.629	76.015	72.483	68.817	67.028	69.279	3600	3609	2605	2413	2704	2432	CAP1	cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030864//cortical actin cytoskeleton;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding	GO:0000902//cell morphogenesis;GO:0001667//ameboidal-type cell migration;GO:0006898//receptor-mediated endocytosis;GO:0007010//cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity;GO:0019933//cAMP-mediated signaling;GO:0030036//actin cytoskeleton organization;GO:0045761//regulation of adenylate cyclase activity	--
ENSG00000131238	50.682	50.873	53.068	52.881	52.976	54.581	2379	2378	1852	1852	2080	1873	PPT1	palmitoyl-protein thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:9325]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation	K01074;K01074;K01074;K01074	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0035727//lysophosphatidic acid binding;GO:0098599//palmitoyl hydrolase activity;GO:0120146//sulfatide binding	GO:0002084//protein depalmitoylation;GO:0006898//receptor-mediated endocytosis;GO:0006907//pinocytosis;GO:0007040//lysosome organization;GO:0007042//lysosomal lumen acidification;GO:0007269//neurotransmitter secretion;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007601//visual perception;GO:0007625//grooming behavior;GO:0008306//associative learning;GO:0008344//adult locomotory behavior;GO:0015031//protein transport;GO:0016042//lipid catabolic process;GO:0030149//sphingolipid catabolic process;GO:0030163//protein catabolic process;GO:0030308//negative regulation of cell growth;GO:0031579//membrane raft organization;GO:0032429//regulation of phospholipase A2 activity;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0044257//cellular protein catabolic process;GO:0044265//cellular macromolecule catabolic process;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048549//positive regulation of pinocytosis;GO:0048666//neuron development;GO:0050803//regulation of synapse structure or activity;GO:0050896//response to stimulus	--
ENSG00000131242	5.466	6.364	5.633	4.804	5.626	5.29	534	539	391	386	433	329	RAB11FIP4	RAB11 family interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:30267]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12485	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow;GO:0055038//recycling endosome membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0032456//endocytic recycling;GO:0032465//regulation of cytokinesis	--
ENSG00000131263	10.221	8.794	7.019	4.769	6.205	7.673	1655	1338	869	647	850	846.02	RLIM	"ring finger protein, LIM domain interacting [Source:HGNC Symbol;Acc:HGNC:13429]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0017053//transcription repressor complex	GO:0003714//transcription corepressor activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060816//random inactivation of X chromosome;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000131264	0	0	0	0	0	0	0	0	0	0	0	0	CDX4	caudal type homeobox 4 [Source:HGNC Symbol;Acc:HGNC:1808]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0009887//animal organ morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060711//labyrinthine layer development"	Homeobox
ENSG00000131269	9.766	9.268	12.511	12.304	10.562	7.882	495	477	289	286	341	270	ABCB7	ATP binding cassette subfamily B member 7 [Source:HGNC Symbol;Acc:HGNC:48]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05662	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015232//heme transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0140359//ABC-type transporter activity;GO:0140481//ABC-type iron-sulfur cluster transporter activity	GO:0006879//cellular iron ion homeostasis;GO:0015886//heme transport;GO:0016226//iron-sulfur cluster assembly;GO:0034755//iron ion transmembrane transport;GO:0055072//iron ion homeostasis;GO:0055085//transmembrane transport;GO:0070455//positive regulation of heme biosynthetic process;GO:0140466//iron-sulfur cluster export from the mitochondrion;GO:1903331//positive regulation of iron-sulfur cluster assembly;GO:1903427//negative regulation of reactive oxygen species biosynthetic process	--
ENSG00000131323	9.433	7.882	6.936	7.607	8.568	8.822	1440	1234	828	844	1098	882	TRAF3	TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Immune system;Immune system;Cancer: specific types;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04668//TNF signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko04622//RIG-I-like receptor signaling pathway	K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174;K03174	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:1902554//serine/threonine protein kinase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008063//Toll signaling pathway;GO:0030162//regulation of proteolysis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032648//regulation of interferon-beta production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050688//regulation of defense response to virus;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0070534//protein K63-linked ubiquitination	--
ENSG00000131351	2.619	3.574	2.869	4.084	1.831	2.259	72	106	56	86	41	47	HAUS8	HAUS augmin like complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:30532]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005880//nuclear microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000131355	0	0	0	0	0	0	0	0	0	0	0	0	ADGRE3	adhesion G protein-coupled receptor E3 [Source:HGNC Symbol;Acc:HGNC:23647]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000131368	20.406	17.082	22.259	23.866	16.142	19.66	1232.95	1127.04	884.05	1102.54	994.42	1011.28	MRPS25	mitochondrial ribosomal protein S25 [Source:HGNC Symbol;Acc:HGNC:14511]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0032543//mitochondrial translation	--
ENSG00000131370	29.77	28.492	29.975	29.64	27.478	32.962	1780	1670	1301	1248	1341	1342	SH3BP5	SH3 domain binding protein 5 [Source:HGNC Symbol;Acc:HGNC:10827]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0004860//protein kinase inhibitor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0006469//negative regulation of protein kinase activity;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000131373	7.221	9.573	8.614	6.704	5.764	6.02	298	391	260	200	196	176	HACL1	2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K12261	GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0030976//thiamine pyrophosphate binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106360//2-hydroxy-3-methylhexadecanoyl-CoA lyase activity;GO:0106376//2-hydroxyphytanoyl-CoA lyase activity	GO:0001561//fatty acid alpha-oxidation;GO:0006625//protein targeting to peroxisome;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0097089//methyl-branched fatty acid metabolic process;GO:1903512//phytanic acid metabolic process	--
ENSG00000131374	12.61	13.022	12.622	11.874	11.931	14.009	1097	1116	732	714	929	846	TBC1D5	TBC1 domain family member 5 [Source:HGNC Symbol;Acc:HGNC:19166]	-	-	-	-	GO:0005768//endosome;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030122//AP-2 adaptor complex;GO:0030904//retromer complex;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1990316//Atg1/ULK1 kinase complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding;GO:0044877//protein-containing complex binding;GO:1905394//retromer complex binding	"GO:0002092//positive regulation of receptor internalization;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0042147//retrograde transport, endosome to Golgi;GO:0042594//response to starvation;GO:0090630//activation of GTPase activity"	--
ENSG00000131375	17.674	17.142	15.364	12.654	13.046	16.591	1450	1283	883	737	878	909	CAPN7	calpain 7 [Source:HGNC Symbol;Acc:HGNC:1484]	-	-	-	-	GO:0005634//nucleus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0090541//MIT domain binding	GO:0006508//proteolysis;GO:0010634//positive regulation of epithelial cell migration;GO:0097264//self proteolysis	--
ENSG00000131378	84.785	97.111	75.492	61.568	67.96	55.537	4013	4514	2674	2331	2968	2074	RFTN1	"raftlin, lipid raft linker 1 [Source:HGNC Symbol;Acc:HGNC:30278]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0003725//double-stranded RNA binding	GO:0001765//membrane raft assembly;GO:0002457//T cell antigen processing and presentation;GO:0032596//protein transport into membrane raft;GO:0032740//positive regulation of interleukin-17 production;GO:0033227//dsRNA transport;GO:0034138//toll-like receptor 3 signaling pathway;GO:0040010//positive regulation of growth rate;GO:0043330//response to exogenous dsRNA;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:1903044//protein localization to membrane raft	--
ENSG00000131379	0	0	0	0	0	0	0	0	0	0	0	0	C3orf20	chromosome 3 open reading frame 20 [Source:HGNC Symbol;Acc:HGNC:25320]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000131381	7.254	7.778	6.482	6.56	8.119	7.233	860	853	625	606	678	622	RBSN	"rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HGNC:20759]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12481	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0034498//early endosome to Golgi transport;GO:0090160//Golgi to lysosome transport;GO:1903358//regulation of Golgi organization	--
ENSG00000131386	0.086	0.141	0.056	0.054	0.338	0.029	9	8	3	2	7	2	GALNT15	polypeptide N-acetylgalactosaminyltransferase 15 [Source:HGNC Symbol;Acc:HGNC:21531]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing	--
ENSG00000131389	7.745	7.927	7.438	7.967	9.089	12.921	995	883	687	780	907	1134	SLC6A6	solute carrier family 6 member 6 [Source:HGNC Symbol;Acc:HGNC:11052]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030425//dendrite;GO:0031528//microvillus membrane;GO:0043025//neuronal cell body;GO:0098797//plasma membrane protein complex;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005368//taurine transmembrane transporter activity;GO:0005369//taurine:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015185//gamma-aminobutyric acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022858//alanine transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0010940//positive regulation of necrotic cell death;GO:0015734//taurine transport;GO:0032328//alanine transport;GO:0035725//sodium ion transmembrane transport;GO:0045597//positive regulation of cell differentiation;GO:0050804//modulation of chemical synaptic transmission;GO:0051939//gamma-aminobutyric acid import;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0089718//amino acid import across plasma membrane;GO:0098739//import across plasma membrane;GO:0150104//transport across blood-brain barrier	--
ENSG00000131398	0.491	0.6	0.658	0.713	0.625	0.591	53	70	42	45	64	59	KCNC3	potassium voltage-gated channel subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:6235]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K04889	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0032591//dendritic spine membrane;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000131400	0	0.059	0.075	0.048	0.07	0.153	0	1	1	1	1	2	NAPSA	napsin A aspartic peptidase [Source:HGNC Symbol;Acc:HGNC:13395]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K08565	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0070062//extracellular exosome;GO:0097208//alveolar lamellar body;GO:0097486//multivesicular body lumen	GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0033619//membrane protein proteolysis;GO:0043129//surfactant homeostasis	--
ENSG00000131408	23.828	21.897	27.774	29.195	23.883	28.807	888	916	767	861	849	818	NR1H2	nuclear receptor subfamily 1 group H member 2 [Source:HGNC Symbol;Acc:HGNC:7965]	Human Diseases	Endocrine and metabolic disease	ko04931//Insulin resistance	K08535	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:0051117//ATPase binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0009755//hormone-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010875//positive regulation of cholesterol efflux;GO:0010884//positive regulation of lipid storage;GO:0010887//negative regulation of cholesterol storage;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0031667//response to nutrient levels;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032369//negative regulation of lipid transport;GO:0032376//positive regulation of cholesterol transport;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042632//cholesterol homeostasis;GO:0042789//mRNA transcription by RNA polymerase II;GO:0044255//cellular lipid metabolic process;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045861//negative regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048550//negative regulation of pinocytosis;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0055088//lipid homeostasis;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0090108//positive regulation of high-density lipoprotein particle assembly;GO:0090187//positive regulation of pancreatic juice secretion;GO:0090340//positive regulation of secretion of lysosomal enzymes;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903573//negative regulation of response to endoplasmic reticulum stress"	THR-like
ENSG00000131409	20.158	20.011	21.765	17.706	20.618	21.17	1320	1336	1061	873	1158	1006	LRRC4B	leucine rich repeat containing 4B [Source:HGNC Symbol;Acc:HGNC:25042]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K16360	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0044300//cerebellar mossy fiber;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly;GO:0099151//regulation of postsynaptic density assembly;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000131435	21.802	23.104	23.486	21.691	20.543	17.158	660	748	545	464	553	413	PDLIM4	PDZ and LIM domain 4 [Source:HGNC Symbol;Acc:HGNC:16501]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031901//early endosome membrane;GO:0031905//early endosome lumen;GO:0031941//filamentous actin;GO:0034777//recycling endosome lumen;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding;GO:0051393//alpha-actinin binding	GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0031532//actin cytoskeleton reorganization;GO:0061061//muscle structure development;GO:0098976//excitatory chemical synaptic transmission	--
ENSG00000131437	3.412	3.188	2.849	1.824	1.643	2.558	350	286	201	129	142	155	KIF3A	kinesin family member 3A [Source:HGNC Symbol;Acc:HGNC:6319]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K10394	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0016939//kinesin II complex;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome;GO:0097470//ribbon synapse;GO:0097542//ciliary tip;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding;GO:0019903//protein phosphatase binding;GO:0030507//spectrin binding;GO:0031267//small GTPase binding;GO:0044877//protein-containing complex binding	GO:0006996//organelle organization;GO:0007018//microtubule-based movement;GO:0008089//anterograde axonal transport;GO:0010457//centriole-centriole cohesion;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0034454//microtubule anchoring at centrosome;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0060271//cilium assembly;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0090316//positive regulation of intracellular protein transport;GO:1902414//protein localization to cell junction;GO:1905128//positive regulation of axo-dendritic protein transport;GO:2000771//positive regulation of establishment or maintenance of cell polarity regulating cell shape	--
ENSG00000131446	30.608	34.72	38.644	32.933	35.631	32.861	2009	2233	1829	1621	1945	1574	MGAT1	"alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7044]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K00726;K00726;K00726	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	"GO:0003827//alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding"	GO:0001701//in utero embryonic development;GO:0006049//UDP-N-acetylglucosamine catabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019082//viral protein processing	--
ENSG00000131459	7.262	6.814	7.745	7.251	8.503	9.063	457	431	360	338	442	415	GFPT2	glutamine-fructose-6-phosphate transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4242]	Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04931//Insulin resistance;ko00520//Amino sugar and nucleotide sugar metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K00820;K00820;K00820;K00820;K00820	GO:0005829//cytosol	GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0097367//carbohydrate derivative binding	GO:0006002//fructose 6-phosphate metabolic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006541//glutamine metabolic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901137//carbohydrate derivative biosynthetic process;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000131462	29.335	28.258	31.031	32.436	30.605	27.561	982.18	950.37	765.73	802.15	864.69	669.9	TUBG1	tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K10389	GO:0000242//pericentriolar material;GO:0000794//condensed nuclear chromosome;GO:0000930//gamma-tubulin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005827//polar microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031252//cell leading edge;GO:0036064//ciliary basal body;GO:0045177//apical part of cell;GO:0055037//recycling endosome;GO:0097730//non-motile cilium;GO:1990498//mitotic spindle microtubule	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0000212//meiotic spindle organization;GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0007020//microtubule nucleation;GO:0007052//mitotic spindle organization;GO:0031122//cytoplasmic microtubule organization	--
ENSG00000131467	34.153	33.705	41.589	37.706	37.067	38.356	2180	2193	1832	1822	1921	1740	PSME3	proteasome activator subunit 3 [Source:HGNC Symbol;Acc:HGNC:9570]	Human Diseases;Organismal Systems;Genetic Information Processing	"Infectious disease: viral;Immune system;Folding, sorting and degradation"	ko05160//Hepatitis C;ko04612//Antigen processing and presentation;ko03050//Proteasome	K06698;K06698;K06698	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0016020//membrane	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0061133//endopeptidase activator activity;GO:0097371//MDM2/MDM4 family protein binding	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0010950//positive regulation of endopeptidase activity;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0061136//regulation of proteasomal protein catabolic process;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000131469	313.992	311.887	320.855	354.894	277.388	302.137	3288	3291	2483	2756	2445	2307	RPL27	ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:10328]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02901;K02901	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0010467//gene expression;GO:1904044//response to aldosterone	--
ENSG00000131470	0.952	0.946	1.311	0.829	0.694	0.807	26.46	26.44	25.29	17.31	15.62	16.65	PSMC3IP	PSMC3 interacting protein [Source:HGNC Symbol;Acc:HGNC:17928]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0120231//DNA recombinase auxiliary factor complex	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0120230//recombinase activator activity	"GO:0000709//meiotic joint molecule formation;GO:0006310//DNA recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0010774//meiotic strand invasion involved in reciprocal meiotic recombination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity;GO:0051321//meiotic cell cycle"	--
ENSG00000131471	3.005	3.939	4.137	3.216	2.805	1.823	245	329	221	196	191	102	AOC3	amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism;ko00350//Tyrosine metabolism;ko00410//beta-Alanine metabolism;ko00360//Phenylalanine metabolism"	K00276;K00276;K00276;K00276;K00276	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008131//primary amine oxidase activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0048038//quinone binding;GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity	GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0009308//amine metabolic process;GO:0046677//response to antibiotic;GO:1902283//negative regulation of primary amine oxidase activity	--
ENSG00000131473	36.44	37.904	33.777	31.842	37.398	34.589	3019	3186	2116	1943	2436	2048	ACLY	ATP citrate lyase [Source:HGNC Symbol;Acc:HGNC:115]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00020//Citrate cycle (TCA cycle)	K01648;K01648	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003878//ATP citrate synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0046912//acyltransferase, acyl groups converted into alkyl on transfer"	GO:0006085//acetyl-CoA biosynthetic process;GO:0006101//citrate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008610//lipid biosynthetic process;GO:0015936//coenzyme A metabolic process	--
ENSG00000131475	37.102	43.787	45.178	46.294	43.546	36.505	835	990	753	771	825	595	VPS25	vacuolar protein sorting 25 homolog [Source:HGNC Symbol;Acc:HGNC:28122]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12189	GO:0000814//ESCRT II complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding	GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission	--
ENSG00000131477	2.072	1.939	0.785	4.641	3.964	3.146	32	31	9	55	51	37	RAMP2	receptor activity modifying protein 2 [Source:HGNC Symbol;Acc:HGNC:9844]	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K08448	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0150057//amylin receptor complex 2;GO:1903143//adrenomedullin receptor complex	GO:0001605//adrenomedullin receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0097643//amylin receptor activity;GO:1990409//adrenomedullin binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0002040//sprouting angiogenesis;GO:0006816//calcium ion transport;GO:0006886//intracellular protein transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007507//heart development;GO:0008217//regulation of blood pressure;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0031623//receptor internalization;GO:0032870//cellular response to hormone stimulus;GO:0034333//adherens junction assembly;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043116//negative regulation of vascular permeability;GO:0045766//positive regulation of angiogenesis;GO:0070830//bicellular tight junction assembly;GO:0070831//basement membrane assembly;GO:0072659//protein localization to plasma membrane;GO:0097084//vascular associated smooth muscle cell development;GO:0097647//amylin receptor signaling pathway;GO:1990410//adrenomedullin receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000131480	1.477	1.339	1.833	0.924	1.398	0.644	82	74	74	38	65	26	AOC2	amine oxidase copper containing 2 [Source:HGNC Symbol;Acc:HGNC:549]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism;ko00350//Tyrosine metabolism;ko00410//beta-Alanine metabolism;ko00360//Phenylalanine metabolism"	K00276;K00276;K00276;K00276;K00276	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008131//primary amine oxidase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0048038//quinone binding;GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity	GO:0006584//catecholamine metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007601//visual perception;GO:0009308//amine metabolic process;GO:0022900//electron transport chain	--
ENSG00000131482	0	0	0	0	0	0	0	0	0	0	0	0	G6PC1	glucose-6-phosphatase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:4056]	Metabolism;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism;Endocrine system;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko04920//Adipocytokine signaling pathway;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0004346//glucose-6-phosphatase activity;GO:0005515//protein binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0016787//hydrolase activity;GO:0042301//phosphate ion binding"	GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0006094//gluconeogenesis;GO:0006641//triglyceride metabolic process;GO:0008202//steroid metabolic process;GO:0010468//regulation of gene expression;GO:0015760//glucose-6-phosphate transport;GO:0016311//dephosphorylation;GO:0035264//multicellular organism growth;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0046415//urate metabolic process;GO:0051156//glucose 6-phosphate metabolic process	--
ENSG00000131495	26.498	23.915	34.322	33.245	28.24	31.186	355	323	340	330	320	304	NDUFA2	NADH:ubiquinone oxidoreductase subunit A2 [Source:HGNC Symbol;Acc:HGNC:7685]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946;K03946	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0001835//blastocyst hatching;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000131503	16.701	12.494	14.074	12.586	14.692	12.405	1441.73	972.38	874.32	727.91	1040.13	846.22	ANKHD1	ankyrin repeat and KH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24714]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0045087//innate immune response	--
ENSG00000131504	17.228	16.814	19.416	13.177	18.011	14.388	1700	1579	1190	1028	1199	976	DIAPH1	diaphanous related formin 1 [Source:HGNC Symbol;Acc:HGNC:2876]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Endocrine and metabolic disease	ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04933//AGE-RAGE signaling pathway in diabetic complications	K05740;K05740;K05740;K05740	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0072686//mitotic spindle;GO:0101003//ficolin-1-rich granule membrane	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding	GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0007605//sensory perception of sound;GO:0008360//regulation of cell shape;GO:0016043//cellular component organization;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030335//positive regulation of cell migration;GO:0032886//regulation of microtubule-based process;GO:0035372//protein localization to microtubule;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0051493//regulation of cytoskeleton organization;GO:0071420//cellular response to histamine	--
ENSG00000131507	52.218	48.851	50.081	49.862	48.203	49.705	3871	3640	2742	2738	3019	2681	NDFIP1	Nedd4 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:17592]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0002761//regulation of myeloid leukocyte differentiation;GO:0002829//negative regulation of type 2 immune response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0007034//vacuolar transport;GO:0010629//negative regulation of gene expression;GO:0030001//metal ion transport;GO:0031398//positive regulation of protein ubiquitination;GO:0032410//negative regulation of transporter activity;GO:0032713//negative regulation of interleukin-4 production;GO:0042130//negative regulation of T cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045619//regulation of lymphocyte differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0050728//negative regulation of inflammatory response;GO:0051224//negative regulation of protein transport	--
ENSG00000131508	38.802	38.471	49.696	42.01	40.968	47.065	1580	1531	1140	1080	1301	1305	UBE2D2	ubiquitin conjugating enzyme E2 D2 [Source:HGNC Symbol;Acc:HGNC:12475]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation;Folding, sorting and degradation"	ko05131//Shigellosis;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K06689;K06689;K06689	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061630//ubiquitin protein ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000131558	27.299	26.402	26.879	24.941	24.63	24.733	2368	2302	1722	1592	1805	1561	EXOC4	exocyst complex component 4 [Source:HGNC Symbol;Acc:HGNC:30389]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K06111	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0032584//growth cone membrane;GO:0035748//myelin sheath abaxonal region;GO:0042995//cell projection;GO:0045202//synapse;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031267//small GTPase binding;GO:0047485//protein N-terminus binding	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0007268//chemical synaptic transmission;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0048341//paraxial mesoderm formation;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000131584	3.949	4.555	5.553	4.884	5.637	6.2	301	347	293	280	352	340	ACAP3	"ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Source:HGNC Symbol;Acc:HGNC:16754]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12489	GO:0030426//growth cone	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001764//neuron migration;GO:0010975//regulation of neuron projection development;GO:0050790//regulation of catalytic activity	--
ENSG00000131591	4.304	3.254	3.807	4.878	4.949	4.94	155	128	105	129	164	142	C1orf159	chromosome 1 open reading frame 159 [Source:HGNC Symbol;Acc:HGNC:26062]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000131620	0	0	0.031	0	0.035	0.02	0	0	1	0	2	1	ANO1	anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0034707//chloride channel complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005227//calcium activated cation channel activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0015111//iodide transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006821//chloride transport;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0015705//iodide transport;GO:0034220//ion transmembrane transport;GO:0034605//cellular response to heat;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport;GO:1901653//cellular response to peptide;GO:1902476//chloride transmembrane transport	--
ENSG00000131626	16.792	14.872	15.125	12.496	14.695	16.732	1550	1432	1076	851	1123	1185	PPFIA1	PTPRF interacting protein alpha 1 [Source:HGNC Symbol;Acc:HGNC:9245]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0048786//presynaptic active zone	GO:0005515//protein binding	GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0050808//synapse organization;GO:0051497//negative regulation of stress fiber assembly;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000131634	0.057	0.028	0	0	0.062	0	2	1	0	0	2	0	TMEM204	transmembrane protein 204 [Source:HGNC Symbol;Acc:HGNC:14158]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	-	GO:0001945//lymph vessel development;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0051145//smooth muscle cell differentiation	--
ENSG00000131650	0.68	0.52	0.521	0.627	0.543	0.414	32	25	17	22	20	12	KREMEN2	kringle containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:18797]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane	-	GO:0016055//Wnt signaling pathway;GO:0030279//negative regulation of ossification;GO:0060173//limb development	--
ENSG00000131652	5.541	6.246	6.288	7.348	7.522	7.374	162.16	183.75	135.39	159	186	156.71	THOC6	THO complex 6 [Source:HGNC Symbol;Acc:HGNC:28369]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K13175	"GO:0000346//transcription export complex;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0008380//RNA splicing;GO:0043066//negative regulation of apoptotic process;GO:0046784//viral mRNA export from host cell nucleus;GO:0051028//mRNA transport	--
ENSG00000131653	26.534	29.015	29.448	35.092	30.658	30.399	1982.38	2155.99	1629.07	1953.32	1925.01	1663.3	TRAF7	TNF receptor associated factor 7 [Source:HGNC Symbol;Acc:HGNC:20456]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0000027//ribosomal large subunit assembly;GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000131668	0	0	0	0	0	0	0	0	0	0	0	0	BARX1	BARX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:955]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0009888//tissue development;GO:0009952//anterior/posterior pattern specification;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0048513//animal organ development;GO:0048536//spleen development;GO:0048856//anatomical structure development;GO:0055123//digestive system development"	Homeobox
ENSG00000131669	40.378	46.53	48.496	49.143	43.271	47.138	1036	1200	919	934	938	880	NINJ1	ninjurin 1 [Source:HGNC Symbol;Acc:HGNC:7824]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0097060//synaptic membrane	GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0098631//cell adhesion mediator activity	GO:0001525//angiogenesis;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0012501//programmed cell death;GO:0019835//cytolysis;GO:0034113//heterotypic cell-cell adhesion;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0042246//tissue regeneration;GO:0042692//muscle cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0050729//positive regulation of inflammatory response;GO:0051260//protein homooligomerization;GO:0070265//necrotic cell death	--
ENSG00000131686	0	0	0	0	0	0	0	0	0	0	0	0	CA6	carbonic anhydrase 6 [Source:HGNC Symbol;Acc:HGNC:1380]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006730//one-carbon metabolic process	--
ENSG00000131697	3.123	3.833	3.138	3.42	3.047	3.518	284	338	206	218	239	234	NPHP4	nephrocystin 4 [Source:HGNC Symbol;Acc:HGNC:19104]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0005929//cilium;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0032391//photoreceptor connecting cilium;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097470//ribbon synapse;GO:0097546//ciliary base;GO:0097730//non-motile cilium;GO:0120206//photoreceptor distal connecting cilium	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007632//visual behavior;GO:0030036//actin cytoskeleton organization;GO:0030317//flagellated sperm motility;GO:0035845//photoreceptor cell outer segment organization;GO:0045494//photoreceptor cell maintenance;GO:0060041//retina development in camera-type eye;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:1903348//positive regulation of bicellular tight junction assembly;GO:1904491//protein localization to ciliary transition zone	--
ENSG00000131711	8.125	6.63	5.901	2.334	2.788	2.824	1521	1337	788	394	576	476	MAP1B	microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043196//varicosity;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0097440//apical dendrite;GO:0097441//basal dendrite;GO:0097457//hippocampal mossy fiber	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008017//microtubule binding;GO:0044877//protein-containing complex binding	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0001764//neuron migration;GO:0007026//negative regulation of microtubule depolymerization;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009612//response to mechanical stimulus;GO:0009743//response to carbohydrate;GO:0010035//response to inorganic substance;GO:0014012//peripheral nervous system axon regeneration;GO:0016358//dendrite development;GO:0017085//response to insecticide;GO:0021700//developmental maturation;GO:0031114//regulation of microtubule depolymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0032387//negative regulation of intracellular transport;GO:0033189//response to vitamin A;GO:0045666//positive regulation of neuron differentiation;GO:0045773//positive regulation of axon extension;GO:0047497//mitochondrion transport along microtubule;GO:0048666//neuron development;GO:0048675//axon extension;GO:0048678//response to axon injury;GO:0051915//induction of synaptic plasticity by chemical substance;GO:0061162//establishment of monopolar cell polarity;GO:0071363//cellular response to growth factor stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0071895//odontoblast differentiation	--
ENSG00000131721	0.051	0	0	0.046	0	0	3	0	0	2	0	0	RHOXF2	Rhox homeobox family member 2 [Source:HGNC Symbol;Acc:HGNC:30011]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression"	Homeobox
ENSG00000131724	19.146	18.146	16.945	12.314	13.738	15.142	1469	1490	1022	756	962	883	IL13RA1	interleukin 13 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:5974]	Human Diseases;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Signal transduction	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05076;K05076;K05076	GO:0005886//plasma membrane;GO:0005898//interleukin-13 receptor complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway	--
ENSG00000131725	5.059	4.507	4.627	3.63	3.958	4.116	429	385	285	229	285	250	WDR44	WD repeat domain 44 [Source:HGNC Symbol;Acc:HGNC:30512]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000131730	9.076	11.834	6.176	6.669	8.887	7.178	219	241	108	124	151	136	CKMT2	"creatine kinase, mitochondrial 2 [Source:HGNC Symbol;Acc:HGNC:1996]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00933;K00933	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004111//creatine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0006936//muscle contraction;GO:0016310//phosphorylation;GO:0019752//carboxylic acid metabolic process;GO:0046314//phosphocreatine biosynthetic process	--
ENSG00000131732	3.88	3.591	3.489	3.323	2.598	3.83	135	119	95	86	86	100	ZCCHC9	zinc finger CCHC-type containing 9 [Source:HGNC Symbol;Acc:HGNC:25424]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000131737	0.029	0	0	0	0	0	1	0	0	0	0	0	KRT34	keratin 34 [Source:HGNC Symbol;Acc:HGNC:6452]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000131738	0.119	0.03	0	0.362	0.282	0.164	4	1	0	9	8	4	KRT33B	keratin 33B [Source:HGNC Symbol;Acc:HGNC:6451]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0007568//aging;GO:0030855//epithelial cell differentiation;GO:0042633//hair cycle;GO:0045109//intermediate filament organization	--
ENSG00000131746	0	0	0	0	0.126	0.016	0	0	0	0	9	1	TNS4	tensin 4 [Source:HGNC Symbol;Acc:HGNC:24352]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0003779//actin binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0008104//protein localization	--
ENSG00000131747	1.481	1.213	1.135	0.8	1.002	0.954	175	144	99	70	100	82	TOP2A	DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989]	Human Diseases	Drug resistance: antineoplastic	ko01524//Platinum drug resistance	K03164	"GO:0000228//nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0009330//DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex;GO:0032991//protein-containing complex;GO:1990904//ribonucleoprotein complex"	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003916//DNA topoisomerase activity;GO:0003918//DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008301//DNA binding, bending;GO:0016853//isomerase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	GO:0000712//resolution of meiotic recombination intermediates;GO:0000819//sister chromatid segregation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006259//DNA metabolic process;GO:0006265//DNA topological change;GO:0006266//DNA ligation;GO:0006974//cellular response to DNA damage stimulus;GO:0007059//chromosome segregation;GO:0007143//female meiotic nuclear division;GO:0030261//chromosome condensation;GO:0030263//apoptotic chromosome condensation;GO:0040016//embryonic cleavage;GO:0042752//regulation of circadian rhythm;GO:0043065//positive regulation of apoptotic process;GO:0045870//positive regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:1905463//negative regulation of DNA duplex unwinding	--
ENSG00000131748	23.354	25.221	28.103	27.043	33.147	25.64	762	817	686	617	864	654	STARD3	StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22291	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044232//organelle membrane contact site;GO:0140284//endoplasmic reticulum-endosome membrane contact site	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0042803//protein homodimerization activity;GO:0120020//cholesterol transfer activity	GO:0006629//lipid metabolic process;GO:0006701//progesterone biosynthetic process;GO:0006839//mitochondrial transport;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0099044//vesicle tethering to endoplasmic reticulum;GO:0120009//intermembrane lipid transfer	--
ENSG00000131759	34.578	35.13	28.806	35.293	42.009	36.687	1669	1766	1133	1297	1786	1372	RARA	retinoic acid receptor alpha [Source:HGNC Symbol;Acc:HGNC:9864]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Endocrine system;Immune system;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04915//Estrogen signaling pathway;ko04659//Th17 cell differentiation;ko05221//Acute myeloid leukemia	K08527;K08527;K08527;K08527;K08527	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0001223//transcription coactivator binding;GO:0001972//retinoic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031490//chromatin DNA binding;GO:0042826//histone deacetylase binding;GO:0043422//protein kinase B binding;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding;GO:0048027//mRNA 5'-UTR binding;GO:0051018//protein kinase A binding;GO:0051393//alpha-actinin binding;GO:1901363//heterocyclic compound binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001657//ureteric bud development;GO:0001843//neural tube closure;GO:0001889//liver development;GO:0002068//glandular epithelial cell development;GO:0003417//growth plate cartilage development;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007281//germ cell development;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0017148//negative regulation of translation;GO:0021766//hippocampus development;GO:0030154//cell differentiation;GO:0030850//prostate gland development;GO:0030852//regulation of granulocyte differentiation;GO:0030853//negative regulation of granulocyte differentiation;GO:0031076//embryonic camera-type eye development;GO:0031641//regulation of myelination;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032689//negative regulation of interferon-gamma production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0033189//response to vitamin A;GO:0034097//response to cytokine;GO:0035264//multicellular organism growth;GO:0042789//mRNA transcription by RNA polymerase II;GO:0042981//regulation of apoptotic process;GO:0043277//apoptotic cell clearance;GO:0045471//response to ethanol;GO:0045596//negative regulation of cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0048384//retinoic acid receptor signaling pathway;GO:0051099//positive regulation of binding;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060010//Sertoli cell fate commitment;GO:0060173//limb development;GO:0060324//face development;GO:0060348//bone development;GO:0060534//trachea cartilage development;GO:0060591//chondroblast differentiation;GO:0061037//negative regulation of cartilage development;GO:0071222//cellular response to lipopolysaccharide;GO:0071300//cellular response to retinoic acid;GO:0071391//cellular response to estrogen stimulus;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II"	THR-like
ENSG00000131771	2.907	3.996	2.864	5.686	6.482	2.286	104	143	75	143	191	59	PPP1R1B	protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Signal transduction;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K15494;K15494;K15494;K15494;K15494	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043025//neuronal cell body	GO:0004860//protein kinase inhibitor activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	"GO:0001975//response to amphetamine;GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0007621//negative regulation of female receptivity;GO:0007626//locomotory behavior;GO:0008542//visual learning;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043278//response to morphine;GO:0048148//behavioral response to cocaine;GO:0071314//cellular response to cocaine;GO:2000480//negative regulation of cAMP-dependent protein kinase activity"	--
ENSG00000131773	2.96	2.921	2.701	1.81	2.508	2.553	102	107	51	50	65	68	KHDRBS3	"KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000131778	9.473	7.888	10.357	8.15	8.425	8.511	546	480	468	349	433	377	CHD1L	chromodomain helicase DNA binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:1916]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006281//DNA repair;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding	--
ENSG00000131779	10.684	11.419	11.242	12.897	12.54	14.234	359	383	279	321	356	348	PEX11B	peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13352	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0007031//peroxisome organization;GO:0007165//signal transduction;GO:0016559//peroxisome fission;GO:0044375//regulation of peroxisome size	--
ENSG00000131781	0.552	0.182	0.288	0.154	0.264	0.388	25	9	10	3	11	14	FMO5	flavin containing dimethylaniline monoxygenase 5 [Source:HGNC Symbol;Acc:HGNC:3773]	Metabolism;Metabolism	Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko00982//Drug metabolism - cytochrome P450;ko00430//Taurine and hypotaurine metabolism	K00485;K00485	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004031//aldehyde oxidase activity;GO:0004497//monooxygenase activity;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0106294//NADPH oxidase H202-forming activity"	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0070995//NADPH oxidation;GO:0090181//regulation of cholesterol metabolic process	--
ENSG00000131788	20.483	20.217	19.52	16.397	19.88	19.03	950.4	1011.37	730.46	612.39	810.59	737.37	PIAS3	protein inhibitor of activated STAT 3 [Source:HGNC Symbol;Acc:HGNC:16861]	Environmental Information Processing;Genetic Information Processing	"Signal transduction;Folding, sorting and degradation"	ko04630//JAK-STAT signaling pathway;ko04120//Ubiquitin mediated proteolysis	K16064;K16064	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0045202//synapse	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0015459//potassium channel regulator activity;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0061665//SUMO ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009725//response to hormone;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016925//protein sumoylation;GO:0033234//negative regulation of protein sumoylation;GO:0033235//positive regulation of protein sumoylation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045838//positive regulation of membrane potential;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060255//regulation of macromolecule metabolic process;GO:0071847//TNFSF11-mediated signaling pathway"	zf-MIZ
ENSG00000131791	4.845	5.108	4.447	4.105	4.785	4.849	537	569	364	337	448	391	PRKAB2	protein kinase AMP-activated non-catalytic subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:9379]	Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04921//Oxytocin signaling pathway;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199;K07199	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031588//nucleotide-activated protein kinase complex	GO:0004679//AMP-activated protein kinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007165//signal transduction;GO:0031669//cellular response to nutrient levels;GO:0050790//regulation of catalytic activity;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000131808	0	0	0	0	0	0	0	0	0	0	0	0	FSHB	follicle stimulating hormone subunit beta [Source:HGNC Symbol;Acc:HGNC:3964]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04912//GnRH signaling pathway;ko04913//Ovarian steroidogenesis	K05250;K05250;K05250;K05250	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016914//follicle-stimulating hormone complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0016913//follicle-stimulating hormone activity	GO:0001541//ovarian follicle development;GO:0006701//progesterone biosynthetic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0010469//regulation of signaling receptor activity;GO:0010628//positive regulation of gene expression;GO:0010893//positive regulation of steroid biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0045670//regulation of osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060011//Sertoli cell proliferation	--
ENSG00000131828	24.79	25.377	28.536	26.571	23.235	27.777	1152.91	1141.53	929.43	892.29	989.37	963.83	PDHA1	pyruvate dehydrogenase E1 subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8806]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Signal transduction;Global and overview maps;Endocrine system;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K00161;K00161;K00161;K00161;K00161;K00161;K00161;K00161;K00161	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045254//pyruvate dehydrogenase complex	"GO:0004738//pyruvate dehydrogenase activity;GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0034604//pyruvate dehydrogenase (NAD+) activity"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0006090//pyruvate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate	--
ENSG00000131831	9.142	9.304	10.127	9.52	10.52	9.584	425	431	345	327	417	321	RAI2	retinoic acid induced 2 [Source:HGNC Symbol;Acc:HGNC:9835]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0009792//embryo development ending in birth or egg hatching;GO:0048513//animal organ development	--
ENSG00000131844	31.247	30.019	30.161	31.835	34.473	32.247	2283	2225	1644	1706	2128	1713	MCCC2	methylcrotonyl-CoA carboxylase subunit 2 [Source:HGNC Symbol;Acc:HGNC:6937]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K01969;K01969	"GO:0002169//3-methylcrotonyl-CoA carboxylase complex, mitochondrial;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1905202//methylcrotonoyl-CoA carboxylase complex"	GO:0000166//nucleotide binding;GO:0004485//methylcrotonoyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006552//leucine catabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0015936//coenzyme A metabolic process;GO:0044281//small molecule metabolic process	--
ENSG00000131845	4.064	4.023	4.782	3.973	3.855	3.768	370	371	324	270	297	248	ZNF304	zinc finger protein 304 [Source:HGNC Symbol;Acc:HGNC:13505]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding"	"GO:0001525//angiogenesis;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007229//integrin-mediated signaling pathway;GO:0007265//Ras protein signal transduction;GO:0030335//positive regulation of cell migration;GO:0035562//negative regulation of chromatin binding;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050679//positive regulation of epithelial cell proliferation;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly;GO:1900114//positive regulation of histone H3-K9 trimethylation;GO:1902466//positive regulation of histone H3-K27 trimethylation;GO:2000811//negative regulation of anoikis"	zf-C2H2
ENSG00000131848	1.932	1.711	3.184	1.614	1.633	1.51	81	74	89	39	66	37	ZSCAN5A	zinc finger and SCAN domain containing 5A [Source:HGNC Symbol;Acc:HGNC:23710]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000131849	1.969	1.814	1.829	1.099	1.503	2.237	121	112	83	50	78	100	ZNF132	zinc finger protein 132 [Source:HGNC Symbol;Acc:HGNC:12916]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000131864	0	0	0	0	0	0	0	0	0	0	0	0	USP29	ubiquitin specific peptidase 29 [Source:HGNC Symbol;Acc:HGNC:18563]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0050821//protein stabilization;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000131871	18.111	19.389	20.253	19.371	16.292	20.418	433	483	359	350	344	352	SELENOS	selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14025	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0036502//Derlin-1-VIMP complex;GO:0036513//Derlin-1 retrotranslocation complex	GO:0005515//protein binding;GO:0016209//antioxidant activity;GO:0019899//enzyme binding;GO:0038023//signaling receptor activity;GO:0051117//ATPase binding;GO:1990381//ubiquitin-specific protease binding	"GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0006111//regulation of gluconeogenesis;GO:0006886//intracellular protein transport;GO:0006983//ER overload response;GO:0009749//response to glucose;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032869//cellular response to insulin stimulus;GO:0034599//cellular response to oxidative stress;GO:0045184//establishment of protein localization;GO:0045454//cell redox homeostasis;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0046325//negative regulation of glucose import;GO:0050728//negative regulation of inflammatory response;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0051775//response to redox state;GO:0071222//cellular response to lipopolysaccharide;GO:0080164//regulation of nitric oxide metabolic process;GO:0098869//cellular oxidant detoxification;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2000110//negative regulation of macrophage apoptotic process"	--
ENSG00000131873	10.635	10.617	8.25	8.752	10.378	8.943	854	862	528	549	658	554	CHSY1	chondroitin sulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:17198]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K13499;K13499	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	GO:0002063//chondrocyte development;GO:0009954//proximal/distal pattern formation;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030279//negative regulation of ossification;GO:0031667//response to nutrient levels;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051216//cartilage development;GO:0051923//sulfation;GO:0060349//bone morphogenesis	--
ENSG00000131876	13.552	13.139	12.901	14.015	12.586	15.292	291	286	207	225	230	240	SNRPA1	small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11092	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005686//U2 snRNP;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0030532//small nuclear ribonucleoprotein complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030620//U2 snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing"	--
ENSG00000131899	9.58	10.283	10.57	10.276	10.139	11.106	837	903	682	665	748.37	706	LLGL1	LLGL scribble cell polarity complex component 1 [Source:HGNC Symbol;Acc:HGNC:6628]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K06094;K06094;K06094	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030424//axon;GO:0030864//cortical actin cytoskeleton;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0042995//cell projection	GO:0005096//GTPase activator activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0045159//myosin II binding	GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0007409//axonogenesis;GO:0008593//regulation of Notch signaling pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0050708//regulation of protein secretion;GO:0050790//regulation of catalytic activity;GO:0051294//establishment of spindle orientation;GO:0065003//protein-containing complex assembly	--
ENSG00000131910	0	0.041	0	0	0	0	0	1	0	0	0	0	NR0B2	nuclear receptor subfamily 0 group B member 2 [Source:HGNC Symbol;Acc:HGNC:7961]	Organismal Systems	Digestive system	ko04976//Bile secretion	K08563	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0044877//protein-containing complex binding;GO:0046965//retinoid X receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007623//circadian rhythm;GO:0008203//cholesterol metabolic process;GO:0009749//response to glucose;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0031100//animal organ regeneration;GO:0032024//positive regulation of insulin secretion;GO:0032922//circadian regulation of gene expression;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045471//response to ethanol;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	Miscellaneous
ENSG00000131914	0	0	0	0	0	0	0	0	0	0	0	0	LIN28A	lin-28 homolog A [Source:HGNC Symbol;Acc:HGNC:15986]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005844//polysome;GO:0010494//cytoplasmic stress granule;GO:1990904//ribonucleoprotein complex	GO:0002151//G-quadruplex RNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031369//translation initiation factor binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:1905538//polysome binding;GO:1990825//sequence-specific mRNA binding	GO:0007281//germ cell development;GO:0010586//miRNA metabolic process;GO:0010587//miRNA catabolic process;GO:0017148//negative regulation of translation;GO:0019827//stem cell population maintenance;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0031123//RNA 3'-end processing;GO:0032008//positive regulation of TOR signaling;GO:0045666//positive regulation of neuron differentiation;GO:0045686//negative regulation of glial cell differentiation;GO:0045727//positive regulation of translation;GO:0048863//stem cell differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0060964//regulation of gene silencing by miRNA;GO:0071076//RNA 3' uridylation;GO:0071333//cellular response to glucose stimulus;GO:1901724//positive regulation of cell proliferation involved in kidney development;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:2000767//positive regulation of cytoplasmic translation	CSD
ENSG00000131931	4.353	4.303	4.734	2.942	3.501	4.911	194	192	156	96	132	158	THAP1	THAP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20856]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001935//endothelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle"	THAP
ENSG00000131941	9.516	8.357	9.826	6.191	7.54	8.479	691	610	527	333	454	448	RHPN2	rhophilin Rho GTPase binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19974]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0003094//glomerular filtration;GO:0007165//signal transduction;GO:0051497//negative regulation of stress fiber assembly	--
ENSG00000131943	15.08	12.87	17.131	13.465	14.469	15.388	721	588	546	476	581	512	C19orf12	chromosome 19 open reading frame 12 [Source:HGNC Symbol;Acc:HGNC:25443]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000131944	3.385	1.838	2.332	1.461	2.25	1.748	96	56	41	25	42	28	FAAP24	FA core complex associated protein 24 [Source:HGNC Symbol;Acc:HGNC:28467]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10898	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0036297//interstrand cross-link repair	--
ENSG00000131951	0.072	0.031	0.028	0.041	0.114	0.014	7	3	2	3	1	1	LRRC9	leucine rich repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:19848]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000131966	30.151	32.475	32.187	26.533	27.156	29.557	990	1139	819	670	789	727	ACTR10	actin related protein 10 [Source:HGNC Symbol;Acc:HGNC:17372]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection	K16576;K16576;K16576;K16576	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0035578//azurophil granule lumen;GO:1904115//axon cytoplasm;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding	GO:0007018//microtubule-based movement;GO:0098958//retrograde axonal transport of mitochondrion	--
ENSG00000131969	0.08	0.243	0.139	0.046	0.181	0	3	8	3	1	5	0	ABHD12B	abhydrolase domain containing 12B [Source:HGNC Symbol;Acc:HGNC:19837]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity	GO:0006660//phosphatidylserine catabolic process;GO:0052651//monoacylglycerol catabolic process;GO:0098734//macromolecule depalmitoylation	--
ENSG00000131979	2.445	2.77	3.646	4.267	4.031	4.685	143	164	160	180	206	203	GCH1	GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K01495;K01495	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0044306//neuron projection terminus	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003924//GTPase activity;GO:0003933//GTP cyclohydrolase activity;GO:0003934//GTP cyclohydrolase I activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0030742//GTP-dependent protein binding;GO:0031369//translation initiation factor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding	"GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0008152//metabolic process;GO:0008217//regulation of blood pressure;GO:0010460//positive regulation of heart rate;GO:0014916//regulation of lung blood pressure;GO:0032496//response to lipopolysaccharide;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:0035998//7,8-dihydroneopterin 3'-triphosphate biosynthetic process;GO:0042311//vasodilation;GO:0042416//dopamine biosynthetic process;GO:0042559//pteridine-containing compound biosynthetic process;GO:0045776//negative regulation of blood pressure;GO:0046654//tetrahydrofolate biosynthetic process;GO:0048265//response to pain;GO:0050884//neuromuscular process controlling posture;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051066//dihydrobiopterin metabolic process;GO:0065003//protein-containing complex assembly;GO:2000121//regulation of removal of superoxide radicals"	--
ENSG00000131981	8.203	8.962	7.495	4.688	6.552	4.98	163	179	110	69	110	72	LGALS3	galectin 3 [Source:HGNC Symbol;Acc:HGNC:6563]	-	-	-	-	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0003723//RNA binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019863//IgE binding;GO:0019903//protein phosphatase binding;GO:0030246//carbohydrate binding;GO:0042056//chemoattractant activity;GO:0043236//laminin binding	GO:0002376//immune system process;GO:0002548//monocyte chemotaxis;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0030593//neutrophil chemotaxis;GO:0030855//epithelial cell differentiation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0042129//regulation of T cell proliferation;GO:0045087//innate immune response;GO:0045806//negative regulation of endocytosis;GO:0048245//eosinophil chemotaxis;GO:0048246//macrophage chemotaxis;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0070232//regulation of T cell apoptotic process;GO:0071674//mononuclear cell migration;GO:0071677//positive regulation of mononuclear cell migration;GO:0090280//positive regulation of calcium ion import;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903614//negative regulation of protein tyrosine phosphatase activity;GO:2000521//negative regulation of immunological synapse formation;GO:2001189//negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000132000	27.449	30.695	22.254	12.77	18.781	10.642	1063	1186	561	391	596	266	PODNL1	podocan like 1 [Source:HGNC Symbol;Acc:HGNC:26275]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000132002	63.952	67.437	68.274	71.665	64.717	66.629	2923	2950	2355	2391	2530	2205	DNAJB1	DnaJ heat shock protein family (Hsp40) member B1 [Source:HGNC Symbol;Acc:HGNC:5270]	Human Diseases;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation"	ko05164//Influenza A;ko04141//Protein processing in endoplasmic reticulum	K09507;K09507	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0061827//sperm head;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0001671//ATPase activator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0044183//protein folding chaperone;GO:0045296//cadherin binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051117//ATPase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0030900//forebrain development;GO:0032781//positive regulation of ATPase activity;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0090084//negative regulation of inclusion body assembly;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:1900034//regulation of cellular response to heat	--
ENSG00000132003	2.614	2.697	2.925	3.026	2.847	2.969	256	265	212	217	236	212	ZSWIM4	zinc finger SWIM-type containing 4 [Source:HGNC Symbol;Acc:HGNC:25704]	-	-	-	-	GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000132004	9.324	9.818	11.202	9.628	11.135	10.114	334	353	296	255	337	263	FBXW9	F-box and WD repeat domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28136]	-	-	-	-	"GO:0005829//cytosol;GO:0030687//preribosome, large subunit precursor"	GO:0005515//protein binding	-	--
ENSG00000132005	3.747	3.797	4.805	3.868	4.427	4.04	340	334	316	260	326	254	RFX1	regulatory factor X1 [Source:HGNC Symbol;Acc:HGNC:9982]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006955//immune response"	RFX
ENSG00000132010	0.906	1.304	0.532	1.177	0.841	0.873	19.44	19.16	17.03	29.79	25.73	16.58	ZNF20	zinc finger protein 20 [Source:HGNC Symbol;Acc:HGNC:12992]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000132016	0.946	1.456	0.789	0.993	0.851	0.675	56	41.18	31	44	39	27	BRME1	break repair meiotic recombinase recruitment factor 1 [Source:HGNC Symbol;Acc:HGNC:28153]	-	-	-	-	GO:0005575//cellular_component;GO:0005694//chromosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007144//female meiosis I;GO:0007283//spermatogenesis;GO:0051321//meiotic cell cycle;GO:1990918//double-strand break repair involved in meiotic recombination	--
ENSG00000132017	8.229	8.991	8.994	9.075	8.566	5.978	323	380	249	265	307	204	DCAF15	DDB1 and CUL4 associated factor 15 [Source:HGNC Symbol;Acc:HGNC:25095]	-	-	-	-	GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0046872//metal ion binding	GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0016567//protein ubiquitination;GO:0032814//regulation of natural killer cell activation	--
ENSG00000132024	15.086	16.394	18.684	19.348	17.715	17.739	1107	1162.82	959	954	1063	944	CC2D1A	coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1905381//negative regulation of snRNA transcription by RNA polymerase II	Others
ENSG00000132026	0	0	0	0	0	0	0	0	0	0	0	0	RTBDN	retbindin [Source:HGNC Symbol;Acc:HGNC:30310]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0033165//interphotoreceptor matrix	GO:0032217//riboflavin transmembrane transporter activity;GO:0038023//signaling receptor activity;GO:1902444//riboflavin binding	GO:0032218//riboflavin transport	--
ENSG00000132031	0.962	0.938	0.919	0.919	0.767	0.674	51	50	36	36	28	26	MATN3	matrilin 3 [Source:HGNC Symbol;Acc:HGNC:6909]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0120216//matrilin complex	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization;GO:0051216//cartilage development	--
ENSG00000132109	7.823	7.015	7.021	6.795	6.635	7.442	314	283	197	202	225	210	TRIM21	tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312]	Human Diseases	Immune disease	ko05322//Systemic lupus erythematosus	K10651	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0031410//cytoplasmic vesicle;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006513//protein monoubiquitination;GO:0007049//cell cycle;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0031648//protein destabilization;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032092//positive regulation of protein binding;GO:0032479//regulation of type I interferon production;GO:0032880//regulation of protein localization;GO:0032897//negative regulation of viral transcription;GO:0034341//response to interferon-gamma;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045787//positive regulation of cell cycle;GO:0045824//negative regulation of innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0046598//positive regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0090086//negative regulation of protein deubiquitination"	--
ENSG00000132122	4.56	4.283	4.014	3.357	3.638	4.504	352	327	224	193	228	263	SPATA6	spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309]	-	-	-	-	GO:0005576//extracellular region;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097224//sperm connecting piece	GO:0005515//protein binding;GO:0032027//myosin light chain binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0044458//motile cilium assembly	--
ENSG00000132128	36.219	39.159	38.875	42.588	42.43	42.498	2208.63	2398	1738	1954	2199.68	1902.71	LRRC41	leucine rich repeat containing 41 [Source:HGNC Symbol;Acc:HGNC:16917]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0016567//protein ubiquitination	--
ENSG00000132141	0.574	0.701	0.814	1.02	0.761	0.809	22	27	22	24	24	17	CCT6B	chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:1901998//toxin transport	--
ENSG00000132153	29.168	29.98	36.158	36.034	32.54	36.382	2300	2363	2103	2103	2168	2084	DHX30	DExH-box helicase 30 [Source:HGNC Symbol;Acc:HGNC:16716]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0035770//ribonucleoprotein granule;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007417//central nervous system development;GO:0042254//ribosome biogenesis;GO:1902775//mitochondrial large ribosomal subunit assembly	--
ENSG00000132155	40.879	40.757	45.296	42.972	45.217	53.257	2793.72	2801.1	2308.38	2178.17	2484.97	2608.8	RAF1	"Raf-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:9829]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Development and regeneration;Infectious disease: viral;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Nervous system;Endocrine system;Immune system;Immune system;Endocrine system;Cancer: overview;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05231//Choline metabolism in cancer;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer"	K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366;K04366	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031143//pseudopodium	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001678//cellular glucose homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0030878//thyroid gland development;GO:0031333//negative regulation of protein-containing complex assembly;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035019//somatic stem cell population maintenance;GO:0035023//regulation of Rho protein signal transduction;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0035994//response to muscle stretch;GO:0042060//wound healing;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045104//intermediate filament cytoskeleton organization;GO:0045595//regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048538//thymus development;GO:0060324//face development;GO:0071550//death-inducing signaling complex assembly;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902531//regulation of intracellular signal transduction;GO:2000145//regulation of cell motility	--
ENSG00000132164	0	0.023	0.031	0	0.013	0	0	2	2	0	1	0	SLC6A11	solute carrier family 6 member 11 [Source:HGNC Symbol;Acc:HGNC:11044]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle	K05044;K05044	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0042165//neurotransmitter binding	GO:0001504//neurotransmitter uptake;GO:0006836//neurotransmitter transport;GO:0007420//brain development;GO:0009410//response to xenobiotic stimulus;GO:0015718//monocarboxylic acid transport;GO:0035725//sodium ion transmembrane transport;GO:0051936//gamma-aminobutyric acid reuptake;GO:0098810//neurotransmitter reuptake	--
ENSG00000132170	0.969	0.546	0.683	0.835	0.813	1.42	37	16	19	24	27	31	PPARG	peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Cancer: overview;Environmental adaptation;Cardiovascular disease;Endocrine and metabolic disease;Development and regeneration;Signal transduction;Aging;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05016//Huntington disease;ko05202//Transcriptional misregulation in cancer;ko04714//Thermogenesis;ko05417//Lipid and atherosclerosis;ko04932//Non-alcoholic fatty liver disease;ko04380//Osteoclast differentiation;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko03320//PPAR signaling pathway;ko05216//Thyroid cancer	K08530;K08530;K08530;K08530;K08530;K08530;K08530;K08530;K08530;K08530;K08530	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0004955//prostaglandin receptor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0030331//estrogen receptor binding;GO:0042277//peptide binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:0050544//arachidonic acid binding;GO:0050692//DNA binding domain binding;GO:0050693//LBD domain binding;GO:0051393//alpha-actinin binding;GO:0070412//R-SMAD binding;GO:0070888//E-box binding;GO:0097677//STAT family protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001890//placenta development;GO:0002674//negative regulation of acute inflammatory response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007507//heart development;GO:0007584//response to nutrient;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0009409//response to cold;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009755//hormone-mediated signaling pathway;GO:0010033//response to organic substance;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010742//macrophage derived foam cell differentiation;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0010888//negative regulation of lipid storage;GO:0010891//negative regulation of sequestering of triglyceride;GO:0014070//response to organic cyclic compound;GO:0015909//long-chain fatty acid transport;GO:0016525//negative regulation of angiogenesis;GO:0019216//regulation of lipid metabolic process;GO:0019395//fatty acid oxidation;GO:0030154//cell differentiation;GO:0030224//monocyte differentiation;GO:0030308//negative regulation of cell growth;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030522//intracellular receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0031000//response to caffeine;GO:0031100//animal organ regeneration;GO:0032869//cellular response to insulin stimulus;GO:0032966//negative regulation of collagen biosynthetic process;GO:0033189//response to vitamin A;GO:0033993//response to lipid;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0035902//response to immobilization stress;GO:0042593//glucose homeostasis;GO:0042594//response to starvation;GO:0042752//regulation of circadian rhythm;GO:0042789//mRNA transcription by RNA polymerase II;GO:0042953//lipoprotein transport;GO:0043065//positive regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0043407//negative regulation of MAP kinase activity;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0043627//response to estrogen;GO:0045087//innate immune response;GO:0045165//cell fate commitment;GO:0045598//regulation of fat cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045923//positive regulation of fatty acid metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046321//positive regulation of fatty acid oxidation;GO:0048384//retinoic acid receptor signaling pathway;GO:0048469//cell maturation;GO:0048511//rhythmic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050728//negative regulation of inflammatory response;GO:0050872//white fat cell differentiation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051716//cellular response to stimulus;GO:0051974//negative regulation of telomerase activity;GO:0055088//lipid homeostasis;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060694//regulation of cholesterol transporter activity;GO:0060965//negative regulation of gene silencing by miRNA;GO:0070165//positive regulation of adiponectin secretion;GO:0071300//cellular response to retinoic acid;GO:0071306//cellular response to vitamin E;GO:0071379//cellular response to prostaglandin stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071455//cellular response to hyperoxia;GO:0071456//cellular response to hypoxia;GO:0090258//negative regulation of mitochondrial fission;GO:1900076//regulation of cellular response to insulin stimulus;GO:1901558//response to metformin;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:1903845//negative regulation of cellular response to transforming growth factor beta stimulus;GO:1904179//positive regulation of adipose tissue development;GO:1904597//negative regulation of connective tissue replacement involved in inflammatory response wound healing;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904893//negative regulation of receptor signaling pathway via STAT;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process;GO:1905563//negative regulation of vascular endothelial cell proliferation;GO:1905599//positive regulation of low-density lipoprotein receptor activity;GO:2000230//negative regulation of pancreatic stellate cell proliferation;GO:2000272//negative regulation of signaling receptor activity"	THR-like
ENSG00000132182	7.97	7.821	8.099	8.992	9.748	8.856	1169	1175	894	963	1231	939	NUP210	nucleoporin 210 [Source:HGNC Symbol;Acc:HGNC:30052]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14314;K14314	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding	GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000132185	0	0	0	0	0	0	0	0	0	0	0	0	FCRLA	Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504]	-	-	-	-	GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane	GO:0004888//transmembrane signaling receptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation	--
ENSG00000132196	10.158	9.543	11.321	9.797	9.859	10.928	317	304	265	230	264	252	HSD17B7	hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215]	Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Lipid metabolism;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis;ko00100//Steroid biosynthesis	K13373;K13373;K13373;K13373	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000253//3-keto sterol reductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0102176//cycloeucalenone reductase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008209//androgen metabolic process	--
ENSG00000132199	17.65	18.032	18.062	18.268	19.948	16.404	666.82	631.8	461.44	517.23	601.05	462.24	ENOSF1	enolase superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:30365]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00051//Fructose and mannose metabolism	K18334;K18334	GO:0005575//cellular_component;GO:0005739//mitochondrion	GO:0000287//magnesium ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0050023//L-fuconate dehydratase activity	GO:0009063//cellular amino acid catabolic process;GO:0016052//carbohydrate catabolic process;GO:0044275//cellular carbohydrate catabolic process	--
ENSG00000132205	0.698	0.847	0.944	1.04	1.21	1.65	86	105	86	95	126	148	EMILIN2	elastin microfibril interfacer 2 [Source:HGNC Symbol;Acc:HGNC:19881]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0062023//collagen-containing extracellular matrix;GO:1990971//EMILIN complex	GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity	GO:0007155//cell adhesion;GO:0008217//regulation of blood pressure;GO:0030194//positive regulation of blood coagulation;GO:0030336//negative regulation of cell migration;GO:0033627//cell adhesion mediated by integrin;GO:0042127//regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:1900426//positive regulation of defense response to bacterium;GO:1901731//positive regulation of platelet aggregation	--
ENSG00000132207	23.34	21.347	28.938	21.274	23.464	24.86	547.5	504.25	500.32	370.33	465.86	425.09	SLX1A	"SLX1 homolog A, structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:20922]"	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15078	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0033557//Slx1-Slx4 complex	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0017108//5'-flap endonuclease activity;GO:0046872//metal ion binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0010833//telomere maintenance via telomere lengthening;GO:0061820//telomeric D-loop disassembly;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090656//t-circle formation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904431//positive regulation of t-circle formation	--
ENSG00000132254	35.125	31.704	36.844	33.761	32.629	34.289	1264	1168	994	914	1004	910	ARFIP2	ADP ribosylation factor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17160]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005543//phospholipid binding;GO:0019904//protein domain specific binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0140090//membrane curvature sensor activity	GO:0000423//mitophagy;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0007264//small GTPase mediated signal transduction;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0031529//ruffle organization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0034497//protein localization to phagophore assembly site	--
ENSG00000132256	8.604	7.053	7.998	6.434	7.318	9.323	544	445	365	290	361	396	TRIM5	tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K10648	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990462//omegasome	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0038187//pattern recognition receptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006914//autophagy;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0070534//protein K63-linked ubiquitination"	--
ENSG00000132259	0	0	0.034	0.034	0.03	0	0	0	1	1	1	0	CNGA4	cyclic nucleotide gated channel subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:2152]	Organismal Systems;Environmental Information Processing	Sensory system;Signal transduction	ko04740//Olfactory transduction;ko04024//cAMP signaling pathway	K04951;K04951	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0060170//ciliary membrane	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0030552//cAMP binding;GO:0030553//cGMP binding	GO:0006811//ion transport;GO:0007608//sensory perception of smell;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000132274	9.835	9.575	9.175	8.341	11.032	9.173	446	419	330	312	412	312	TRIM22	tripartite motif containing 22 [Source:HGNC Symbol;Acc:HGNC:16379]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0016607//nuclear speck	GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006955//immune response;GO:0009615//response to virus;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus"	--
ENSG00000132275	6.684	8.489	7.699	8.389	8.009	8.124	291	334	260	258	259	242	RRP8	ribosomal RNA processing 8 [Source:HGNC Symbol;Acc:HGNC:29030]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0033553//rDNA heterochromatin;GO:0061773//eNoSc complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0035064//methylated histone binding	"GO:0000183//rDNA heterochromatin assembly;GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0031062//positive regulation of histone methylation;GO:0031065//positive regulation of histone deacetylation;GO:0032259//methylation;GO:0042149//cellular response to glucose starvation;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046015//regulation of transcription by glucose;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0097009//energy homeostasis;GO:1903450//regulation of G1 to G0 transition"	--
ENSG00000132286	12.975	11.678	14.63	15.861	16.73	16.358	702	670	542	612	593	595	TIMM10B	translocase of inner mitochondrial membrane 10B [Source:HGNC Symbol;Acc:HGNC:4022]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0140318//protein transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0007160//cell-matrix adhesion;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000132294	18.752	15.895	17.415	14.996	15.642	16.361	1967	1741	1330	1190	1348	1336	EFR3A	EFR3 homolog A [Source:HGNC Symbol;Acc:HGNC:28970]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	-	GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000132297	0	0	0	0	0	0	0	0	0	0	0	0	HHLA1	HERV-H LTR-associating 1 [Source:HGNC Symbol;Acc:HGNC:4904]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000132300	15.998	58.383	9.371	37.463	20.124	47.944	913	783	603	493	597	513	PTCD3	pentatricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:24717]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0043024//ribosomal small subunit binding	GO:0006417//regulation of translation;GO:0032543//mitochondrial translation	--
ENSG00000132305	26.521	27.177	27.725	24.66	22.579	25.899	1462	1512	1133	1007	1054	1041	IMMT	inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047]	-	-	-	-	GO:0001401//SAM complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0110165//cellular anatomical entity;GO:0140275//MIB complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000132313	13.098	13.673	16.447	15.627	15.836	15.238	544	501	454	398	492	457	MRPL35	mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489]	Genetic Information Processing	Translation	ko03010//Ribosome	K02916	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000132321	6.498	5.953	5.026	3.618	3.853	4.331	426	392	245	174	213	205	IQCA1	IQ motif containing with AAA domain 1 [Source:HGNC Symbol;Acc:HGNC:26195]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000132323	8.262	8.043	7.946	7.997	7.998	7.521	247	238	166	176	202	152	ILKAP	ILK associated serine/threonine phosphatase [Source:HGNC Symbol;Acc:HGNC:15566]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007229//integrin-mediated signaling pathway;GO:0016310//phosphorylation	--
ENSG00000132326	0.272	0.15	0.225	0.439	0.376	0.187	36	20	22	43	42	18	PER2	period circadian regulator 2 [Source:HGNC Symbol;Acc:HGNC:8846]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Environmental adaptation;Cancer: specific types;Environmental adaptation	ko05202//Transcriptional misregulation in cancer;ko04713//Circadian entrainment;ko05221//Acute myeloid leukemia;ko04710//Circadian rhythm	K02633;K02633;K02633;K02633	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0000976//transcription cis-regulatory region binding;GO:0001222//transcription corepressor binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002931//response to ischemia;GO:0005978//glycogen biosynthetic process;GO:0006094//gluconeogenesis;GO:0006631//fatty acid metabolic process;GO:0007623//circadian rhythm;GO:0019229//regulation of vasoconstriction;GO:0019249//lactate biosynthetic process;GO:0031397//negative regulation of protein ubiquitination;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0042754//negative regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis;GO:0050796//regulation of insulin secretion;GO:0050872//white fat cell differentiation;GO:0051726//regulation of cell cycle;GO:0051946//regulation of glutamate uptake involved in transmission of nerve impulse;GO:0070345//negative regulation of fat cell proliferation;GO:0070932//histone H3 deacetylation;GO:0097167//circadian regulation of translation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:2000678//negative regulation of transcription regulatory region DNA binding"	--
ENSG00000132329	22.319	24.268	19.901	12.021	12.689	13.365	381	413	251	152	183	166	RAMP1	receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843]	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K08447	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0150056//amylin receptor complex 1;GO:1990406//CGRP receptor complex	GO:0001635//calcitonin gene-related peptide receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0097643//amylin receptor activity;GO:1990407//calcitonin gene-related peptide binding	GO:0001525//angiogenesis;GO:0006816//calcium ion transport;GO:0006886//intracellular protein transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0015031//protein transport;GO:0031623//receptor internalization;GO:0032870//cellular response to hormone stimulus;GO:0060050//positive regulation of protein glycosylation;GO:0072659//protein localization to plasma membrane;GO:0097647//amylin receptor signaling pathway;GO:1990408//calcitonin gene-related peptide receptor signaling pathway	--
ENSG00000132330	7.721	6	8.629	7.057	6.469	7.754	325	280	260	245	265	268	SCLY	selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:18161]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00450//Selenocompound metabolism	K01763;K01763	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:1902494//catalytic complex	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0009000//selenocysteine lyase activity;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0042803//protein homodimerization activity;GO:0070279//vitamin B6 binding	GO:0006520//cellular amino acid metabolic process;GO:0016261//selenocysteine catabolic process	--
ENSG00000132334	4.908	5.196	4.258	3.839	3.819	3.823	539	570	345	288	354	281	PTPRE	protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway	--
ENSG00000132341	107.861	116.908	112.756	119.985	105.709	117.811	3178	3279	2369	2443	2592	2241	RAN	"RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846]"	Human Diseases;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Translation;Translation	ko05166//Human T-cell leukemia virus 1 infection;ko03013//Nucleocytoplasmic transport;ko03008//Ribosome biogenesis in eukaryotes	K07936;K07936;K07936	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0016020//membrane;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0042470//melanosome;GO:0042565//RNA nuclear export complex;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0070883//pre-miRNA binding	GO:0000054//ribosomal subunit export from nucleus;GO:0000055//ribosomal large subunit export from nucleus;GO:0000056//ribosomal small subunit export from nucleus;GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0015031//protein transport;GO:0016032//viral process;GO:0032092//positive regulation of protein binding;GO:0035281//pre-miRNA export from nucleus;GO:0042307//positive regulation of protein import into nucleus;GO:0046039//GTP metabolic process;GO:0051301//cell division;GO:0061015//snRNA import into nucleus;GO:1902570//protein localization to nucleolus	--
ENSG00000132356	11.525	8.686	9.529	6.869	8.611	10.435	1144	819	731	523	727	735	PRKAA1	protein kinase AMP-activated catalytic subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:9376]	Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Signal transduction;Endocrine system;Transport and catabolism;Endocrine and metabolic disease;Endocrine system;Signal transduction;Cardiovascular disease;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04151//PI3K-Akt signaling pathway;ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016324//apical plasma membrane;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:0031588//nucleotide-activated protein kinase complex;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035174//histone serine kinase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0106310//protein serine kinase activity	GO:0001666//response to hypoxia;GO:0006006//glucose metabolic process;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008610//lipid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0009631//cold acclimation;GO:0010332//response to gamma radiation;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014823//response to activity;GO:0015721//bile acid and bile salt transport;GO:0016055//Wnt signaling pathway;GO:0016126//sterol biosynthetic process;GO:0016310//phosphorylation;GO:0019395//fatty acid oxidation;GO:0031000//response to caffeine;GO:0031669//cellular response to nutrient levels;GO:0032007//negative regulation of TOR signaling;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0034599//cellular response to oxidative stress;GO:0035404//histone-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0038183//bile acid signaling pathway;GO:0042149//cellular response to glucose starvation;GO:0042542//response to hydrogen peroxide;GO:0042593//glucose homeostasis;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0045821//positive regulation of glycolytic process;GO:0046318//negative regulation of glucosylceramide biosynthetic process;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048511//rhythmic process;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0050995//negative regulation of lipid catabolic process;GO:0055089//fatty acid homeostasis;GO:0060627//regulation of vesicle-mediated transport;GO:0061744//motor behavior;GO:0061762//CAMKK-AMPK signaling cascade;GO:0062028//regulation of stress granule assembly;GO:0070050//neuron cellular homeostasis;GO:0070301//cellular response to hydrogen peroxide;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071277//cellular response to calcium ion;GO:0071333//cellular response to glucose stimulus;GO:0071361//cellular response to ethanol;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071417//cellular response to organonitrogen compound;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0097009//energy homeostasis;GO:0120188//regulation of bile acid secretion;GO:1901563//response to camptothecin;GO:1903109//positive regulation of mitochondrial transcription;GO:1903829//positive regulation of cellular protein localization;GO:1903944//negative regulation of hepatocyte apoptotic process;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1904428//negative regulation of tubulin deacetylation;GO:1904486//response to 17alpha-ethynylestradiol;GO:1905691//lipid droplet disassembly;GO:1990044//protein localization to lipid droplet;GO:2000758//positive regulation of peptidyl-lysine acetylation	--
ENSG00000132357	1.146	0.843	1.042	0.887	1.117	0.909	96	71	59	55	71	51	CARD6	caspase recruitment domain family member 6 [Source:HGNC Symbol;Acc:HGNC:16394]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12797	-	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process	--
ENSG00000132359	0.146	0.306	0.149	0.285	0.313	0.47	15	32	8	29	35	37	RAP1GAP2	RAP1 GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:29176]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0008361//regulation of cell size;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000132361	13.583	12.364	13.801	15.226	17.134	16.623	1282	1366	1127	1248	1435	1205	CLUH	clustered mitochondria homolog [Source:HGNC Symbol;Acc:HGNC:29094]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006996//organelle organization;GO:0007005//mitochondrion organization;GO:0048312//intracellular distribution of mitochondria	--
ENSG00000132376	210.657	225.058	243.773	256.916	256.634	216.681	7506	8040	6356	6857	7878	5538	INPP5K	inositol polyphosphate-5-phosphatase K [Source:HGNC Symbol;Acc:HGNC:33882]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism	K24222;K24222	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0005000//vasopressin receptor activity;GO:0005515//protein binding;GO:0016312//inositol bisphosphate phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"	"GO:0001701//in utero embryonic development;GO:0001933//negative regulation of protein phosphorylation;GO:0005979//regulation of glycogen biosynthetic process;GO:0006469//negative regulation of protein kinase activity;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010829//negative regulation of glucose transmembrane transport;GO:0016311//dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0032870//cellular response to hormone stimulus;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0035810//positive regulation of urine volume;GO:0042593//glucose homeostasis;GO:0043407//negative regulation of MAP kinase activity;GO:0043922//negative regulation by host of viral transcription;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0051497//negative regulation of stress fiber assembly;GO:0051898//negative regulation of protein kinase B signaling;GO:0051926//negative regulation of calcium ion transport;GO:0071320//cellular response to cAMP;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072659//protein localization to plasma membrane;GO:0090315//negative regulation of protein targeting to membrane;GO:0097178//ruffle assembly;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:2001153//positive regulation of renal water transport"	--
ENSG00000132382	6.194	7.406	7.456	5.879	8.807	6.171	575	646.09	515	406	664	362	MYBBP1A	MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0042564//NLS-dependent protein nuclear import complex;GO:0043231//intracellular membrane-bounded organelle;GO:0110016//B-WICH complex	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0070888//E-box binding	"GO:0001649//osteoblast differentiation;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0022904//respiratory electron transport chain;GO:0032922//circadian regulation of gene expression;GO:0035066//positive regulation of histone acetylation;GO:0042149//cellular response to glucose starvation;GO:0042254//ribosome biogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0048511//rhythmic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1903450//regulation of G1 to G0 transition;GO:2000210//positive regulation of anoikis"	--
ENSG00000132383	15.499	15.923	15.467	14.015	13.622	16.774	1506	1566	1121	1011	1157	1063	RPA1	replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03430//Mismatch repair	K07466;K07466;K07466;K07466;K07466	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0016605//PML body;GO:0090734//site of DNA damage"	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0043047//single-stranded telomeric DNA binding;GO:0046872//metal ion binding;GO:0098505//G-rich strand telomeric DNA binding	GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006289//nucleotide-excision repair;GO:0006298//mismatch repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007004//telomere maintenance via telomerase;GO:0034502//protein localization to chromosome;GO:0051321//meiotic cell cycle	--
ENSG00000132386	8956.982	9708.673	9643.098	9114.61	9223.085	9199.321	256858	279728	204771	195566	223254	192640	SERPINF1	serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K19614	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0030424//axon;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0043203//axon hillock;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding	GO:0001822//kidney development;GO:0007568//aging;GO:0007614//short-term memory;GO:0010447//response to acidic pH;GO:0010596//negative regulation of endothelial cell migration;GO:0010629//negative regulation of gene expression;GO:0010951//negative regulation of endopeptidase activity;GO:0010976//positive regulation of neuron projection development;GO:0014070//response to organic cyclic compound;GO:0016525//negative regulation of angiogenesis;GO:0042698//ovulation cycle;GO:0046685//response to arsenic-containing substance;GO:0050728//negative regulation of inflammatory response;GO:0050769//positive regulation of neurogenesis;GO:0060041//retina development in camera-type eye;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0071279//cellular response to cobalt ion;GO:0071300//cellular response to retinoic acid;GO:0071333//cellular response to glucose stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:1901215//negative regulation of neuron death;GO:1901652//response to peptide	--
ENSG00000132388	21.38	24.318	27.541	26.391	22.293	29.512	1452	1462	1153	1092	1198	1256	UBE2G1	ubiquitin conjugating enzyme E2 G1 [Source:HGNC Symbol;Acc:HGNC:12482]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K10575;K10575;K10575;K10575	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044257//cellular protein catabolic process;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000132394	12.985	13.498	13.822	16.045	15.435	11.561	589.47	619.38	465.17	540.39	592.81	383.28	EEFSEC	"eukaryotic elongation factor, selenocysteine-tRNA specific [Source:HGNC Symbol;Acc:HGNC:24614]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0035368//selenocysteine insertion sequence binding;GO:0043021//ribonucleoprotein complex binding	GO:0001514//selenocysteine incorporation;GO:0006412//translation;GO:0006414//translational elongation	--
ENSG00000132405	78.553	73.845	83.025	68.963	68.521	88.217	7717	7305	6089	5011	5671	6404	TBC1D14	TBC1 domain family member 14 [Source:HGNC Symbol;Acc:HGNC:29246]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006914//autophagy;GO:0010507//negative regulation of autophagy;GO:0071955//recycling endosome to Golgi transport;GO:0090630//activation of GTPase activity;GO:2000785//regulation of autophagosome assembly	--
ENSG00000132406	9.274	11.449	11.328	10.656	10.964	11.476	245	302	221	206	246	222	TMEM128	transmembrane protein 128 [Source:HGNC Symbol;Acc:HGNC:28201]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000132423	1.63	1.195	2.069	2.21	1.464	2.284	43	33	42	45	34	44	COQ3	"coenzyme Q3, methyltransferase [Source:HGNC Symbol;Acc:HGNC:18175]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K00591;K00591	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0110142//ubiquinone biosynthesis complex	"GO:0004395//hexaprenyldihydroxybenzoate methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0008689//3-demethylubiquinone-9 3-O-methyltransferase activity;GO:0010420//3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity;GO:0016740//transferase activity;GO:0044595//decaprenyldihydroxybenzoate methyltransferase activity;GO:0044596//3-demethylubiquinol-10 3-O-methyltransferase activity"	GO:0006071//glycerol metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0008152//metabolic process;GO:0010795//regulation of ubiquinone biosynthetic process;GO:0032259//methylation	--
ENSG00000132424	10.022	7.991	7.502	6.912	8.779	10.015	693	565	398	342	510	516	PNISR	PNN interacting serine and arginine rich protein [Source:HGNC Symbol;Acc:HGNC:21222]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0048786//presynaptic active zone	GO:0003723//RNA binding	-	--
ENSG00000132429	2.369	1.557	1.077	1.42	1.154	1.446	80	61	31	41	38	41	POPDC3	popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0030552//cAMP binding	GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0008150//biological_process;GO:0042391//regulation of membrane potential;GO:0051146//striated muscle cell differentiation	--
ENSG00000132432	34.568	35.955	33.774	32.774	31.82	32.077	318	330	232	226	248	218	SEC61G	SEC61 translocon subunit gamma [Source:HGNC Symbol;Acc:HGNC:18277]	Cellular Processes;Genetic Information Processing;Human Diseases;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation;Infectious disease: bacterial;Folding, sorting and degradation"	ko04145//Phagosome;ko04141//Protein processing in endoplasmic reticulum;ko05110//Vibrio cholerae infection;ko03060//Protein export	K07342;K07342;K07342;K07342	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071261//Ssh1 translocon complex	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0043022//ribosome binding	"GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0031204//posttranslational protein targeting to membrane, translocation;GO:0045047//protein targeting to ER;GO:0071806//protein transmembrane transport"	--
ENSG00000132434	7.57	8.456	7.247	6.355	8.096	6.024	569	589	419	404	494	355	LANCL2	LanC like 2 [Source:HGNC Symbol;Acc:HGNC:6509]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030864//cortical actin cytoskeleton	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding	"GO:0005975//carbohydrate metabolic process;GO:0009789//positive regulation of abscisic acid-activated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000132436	2.639	2.382	2.555	2.061	1.861	2.211	191	166	137	98	114	118	FIGNL1	fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008568//microtubule-severing ATPase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0001649//osteoblast differentiation;GO:0007140//male meiotic nuclear division;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0033687//osteoblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0046034//ATP metabolic process;GO:0051013//microtubule severing;GO:0051726//regulation of cell cycle;GO:0071479//cellular response to ionizing radiation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000132437	0	0.065	0	0	0	0	0	2	0	0	0	0	DDC	dopa decarboxylase [Source:HGNC Symbol;Acc:HGNC:2719]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Substance dependence;Nervous system;Nervous system;Substance dependence;Substance dependence;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko05031//Amphetamine addiction;ko05030//Cocaine addiction;ko00380//Tryptophan metabolism;ko00350//Tyrosine metabolism;ko00360//Phenylalanine metabolism	K01593;K01593;K01593;K01593;K01593;K01593;K01593;K01593;K01593	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004058//aromatic-L-amino-acid decarboxylase activity;GO:0005515//protein binding;GO:0016597//amino acid binding;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0030170//pyridoxal phosphate binding;GO:0036467//5-hydroxy-L-tryptophan decarboxylase activity;GO:0036468//L-dopa decarboxylase activity	GO:0006520//cellular amino acid metabolic process;GO:0006584//catecholamine metabolic process;GO:0007623//circadian rhythm;GO:0009636//response to toxic substance;GO:0010259//multicellular organism aging;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0019752//carboxylic acid metabolic process;GO:0033076//isoquinoline alkaloid metabolic process;GO:0042416//dopamine biosynthetic process;GO:0042423//catecholamine biosynthetic process;GO:0042427//serotonin biosynthetic process;GO:0046684//response to pyrethroid;GO:0052314//phytoalexin metabolic process;GO:0071312//cellular response to alkaloid;GO:0071363//cellular response to growth factor stimulus;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000132446	0	0	0	0	0	0	0	0	0	0	0	0	FTHL17	ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987]	Cellular Processes;Organismal Systems;Cellular Processes	Cell growth and death;Digestive system;Cell growth and death	ko04217//Necroptosis;ko04978//Mineral absorption;ko04216//Ferroptosis	K00522;K00522;K00522	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0046872//metal ion binding	GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006880//intracellular sequestering of iron ion	--
ENSG00000132463	37.793	36.41	34.094	31.86	30.839	36.289	2121	2090	1438	1267	1478	1443	GRSF1	G-rich RNA sequence binding factor 1 [Source:HGNC Symbol;Acc:HGNC:4610]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule;GO:0042645//mitochondrial nucleoid;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0006378//mRNA polyadenylation;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008033//tRNA processing;GO:0009952//anterior/posterior pattern specification;GO:0016331//morphogenesis of embryonic epithelium;GO:0043484//regulation of RNA splicing	--
ENSG00000132464	0.034	0.008	0	0.034	0	0.035	4	1	0	3	0	3	ENAM	enamelin [Source:HGNC Symbol;Acc:HGNC:3344]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0030345//structural constituent of tooth enamel	GO:0031214//biomineral tissue development;GO:0036305//ameloblast differentiation;GO:0070175//positive regulation of enamel mineralization;GO:0097186//amelogenesis	--
ENSG00000132465	0	0.149	0	0	0.666	0.052	0	4	0	0	15	1	JCHAIN	joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071750//dimeric IgA immunoglobulin complex;GO:0071751//secretory IgA immunoglobulin complex;GO:0071752//secretory dimeric IgA immunoglobulin complex;GO:0071756//pentameric IgM immunoglobulin complex;GO:0072562//blood microparticle	GO:0003697//single-stranded DNA binding;GO:0003823//antigen binding;GO:0019862//IgA binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031210//phosphatidylcholine binding;GO:0034987//immunoglobulin receptor binding;GO:0042803//protein homodimerization activity;GO:0042834//peptidoglycan binding	GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0003094//glomerular filtration;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response;GO:0060267//positive regulation of respiratory burst;GO:0065003//protein-containing complex assembly	--
ENSG00000132466	17.03	15.339	15.18	11.072	13.032	12.55	2945	2679	1973	1420	1889	1581	ANKRD17	ankyrin repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:23575]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0001955//blood vessel maturation;GO:0002376//immune system process;GO:0006275//regulation of DNA replication;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045787//positive regulation of cell cycle;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000132467	8.067	7.978	9.662	8.732	9.294	8.988	338	336	299	271	329	274	UTP3	UTP3 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24477]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006325//chromatin organization;GO:0007420//brain development"	--
ENSG00000132470	88.54	98.455	81.18	59.041	67.721	57.279	10167	11491	6961	5105	6671	4826	ITGB4	integrin subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:6158]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06525;K06525;K06525;K06525;K06525;K06525;K06525;K06525	GO:0005604//basement membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0031252//cell leading edge;GO:0031965//nuclear membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0001664//G protein-coupled receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0031994//insulin-like growth factor I binding;GO:0038132//neuregulin binding	GO:0006914//autophagy;GO:0007154//cell communication;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0009611//response to wounding;GO:0016477//cell migration;GO:0022011//myelination in peripheral nervous system;GO:0031581//hemidesmosome assembly;GO:0032290//peripheral nervous system myelin formation;GO:0033627//cell adhesion mediated by integrin;GO:0035878//nail development;GO:0043589//skin morphogenesis;GO:0046847//filopodium assembly;GO:0048333//mesodermal cell differentiation;GO:0048870//cell motility;GO:0061450//trophoblast cell migration	--
ENSG00000132471	166.337	166.414	173.588	201.932	195.216	179.136	6214	6338	4898	5609	6188	4943	WBP2	WW domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:12738]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0031490//chromatin DNA binding	"GO:0032570//response to progesterone;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0043627//response to estrogen;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050847//progesterone receptor signaling pathway;GO:0071169//establishment of protein localization to chromatin;GO:0071391//cellular response to estrogen stimulus;GO:0071442//positive regulation of histone H3-K14 acetylation"	--
ENSG00000132475	172.984	181.555	182.3	180.231	184.629	176.614	5033	5347	3799	3755	4265	3469	H3-3B	H3.3 histone B [Source:HGNC Symbol;Acc:HGNC:4765]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome"	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0030307//positive regulation of cell growth;GO:0032200//telomere organization	--
ENSG00000132478	16.75	16.441	18.944	15.02	15.973	18.32	948	974	786	689	851	766	UNK	unk zinc finger [Source:HGNC Symbol;Acc:HGNC:29369]	-	-	-	-	GO:0005737//cytoplasm;GO:0005844//polysome	GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:1905538//polysome binding;GO:1990715//mRNA CDS binding	GO:0001701//in utero embryonic development;GO:0001764//neuron migration;GO:0006417//regulation of translation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:2000766//negative regulation of cytoplasmic translation	--
ENSG00000132481	33.705	34.941	33.715	32.597	34.818	40.861	1532	1551	1112	1076	1275	1311	TRIM47	tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000132485	19.686	17.662	16.802	16.736	16.293	19.729	1117	947	635	634	742	753	ZRANB2	zinc finger RANBP2-type containing 2 [Source:HGNC Symbol;Acc:HGNC:13058]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0001530//lipopolysaccharide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000132507	98.078	93.092	104.334	105.188	92.251	99.173	2495	2424	1975	1994	2022	1822	EIF5A	eukaryotic translation initiation factor 5A [Source:HGNC Symbol;Acc:HGNC:3300]	-	-	-	-	GO:0005634//nucleus;GO:0005642//annulate lamellae;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0043022//ribosome binding;GO:0047485//protein N-terminus binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0015031//protein transport;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045901//positive regulation of translational elongation;GO:0045905//positive regulation of translational termination;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:0098586//cellular response to virus;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000132510	3.856	4.241	4.133	4.287	4.555	5.073	538	582	426	443	537	515	KDM6B	lysine demethylase 6B [Source:HGNC Symbol;Acc:HGNC:29012]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0044666//MLL3/4 complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032452//histone demethylase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0071558//histone H3-tri/di-methyl-lysine-27 demethylase activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006954//inflammatory response;GO:0007507//heart development;GO:0010468//regulation of gene expression;GO:0016577//histone demethylation;GO:0045165//cell fate commitment;GO:0045446//endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048333//mesodermal cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0070301//cellular response to hydrogen peroxide;GO:0071557//histone H3-K27 demethylation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000132514	0	0	0	0	0	0	0	0	0	0	0	0	CLEC10A	C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006897//endocytosis;GO:0045087//innate immune response	--
ENSG00000132517	0	0	0	0	0	0	0	0	0	0	0	0	SLC52A1	solute carrier family 52 member 1 [Source:HGNC Symbol;Acc:HGNC:30225]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0032217//riboflavin transmembrane transporter activity	GO:0006771//riboflavin metabolic process;GO:0032218//riboflavin transport;GO:0046718//viral entry into host cell	--
ENSG00000132518	0.013	0.039	0.018	0	0	0.054	1	3	1	0	0	3	GUCY2D	"guanylate cyclase 2D, retinal [Source:HGNC Symbol;Acc:HGNC:4689]"	Metabolism;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Sensory system;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko04740//Olfactory transduction;ko00230//Purine metabolism;ko04744//Phototransduction	K12321;K12321;K12321;K12321	GO:0001750//photoreceptor outer segment;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection;GO:0097381//photoreceptor disc membrane	GO:0000166//nucleotide binding;GO:0001653//peptide receptor activity;GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding	GO:0006182//cGMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007601//visual perception;GO:0009190//cyclic nucleotide biosynthetic process;GO:0019934//cGMP-mediated signaling;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0035556//intracellular signal transduction;GO:0050896//response to stimulus	--
ENSG00000132522	36.764	36.763	37.324	39.705	40.111	36.399	939.38	916.39	701.1	734.26	844.59	674.05	GPS2	G protein pathway suppressor 2 [Source:HGNC Symbol;Acc:HGNC:4550]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K15307	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0017053//transcription repressor complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0030332//cyclin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007254//JNK cascade;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010875//positive regulation of cholesterol efflux;GO:0019216//regulation of lipid metabolic process;GO:0030183//B cell differentiation;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0045598//regulation of fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0050728//negative regulation of inflammatory response;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0098780//response to mitochondrial depolarisation;GO:1900045//negative regulation of protein K63-linked ubiquitination	--
ENSG00000132530	0	0.014	0	0	0.033	0	0	1	0	0	2	0	XAF1	XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0035456//response to interferon-beta	--
ENSG00000132535	7.643	8.464	7.97	8.145	8.849	10.574	478	496	357	351	426	446	DLG4	discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease;ko04390//Hippo signaling pathway;ko04724//Glutamatergic synapse;ko05030//Cocaine addiction	K11828;K11828;K11828;K11828;K11828	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0008021//synaptic vesicle;GO:0008076//voltage-gated potassium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0030863//cortical cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031594//neuromuscular junction;GO:0032281//AMPA glutamate receptor complex;GO:0032839//dendrite cytoplasm;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0044224//juxtaparanode region of axon;GO:0044300//cerebellar mossy fiber;GO:0044306//neuron projection terminus;GO:0044309//neuron spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0071944//cell periphery;GO:0097060//synaptic membrane;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099031//anchored component of postsynaptic density membrane;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019865//immunoglobulin binding;GO:0019894//kinesin binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030165//PDZ domain binding;GO:0031697//beta-1 adrenergic receptor binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0031748//D1 dopamine receptor binding;GO:0031812//P2Y1 nucleotide receptor binding;GO:0033130//acetylcholine receptor binding;GO:0035254//glutamate receptor binding;GO:0035255//ionotropic glutamate receptor binding;GO:0044877//protein-containing complex binding;GO:0097109//neuroligin family protein binding;GO:0097110//scaffold protein binding;GO:0098919//structural constituent of postsynaptic density	GO:0002091//negative regulation of receptor internalization;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007612//learning;GO:0016188//synaptic vesicle maturation;GO:0035176//social behavior;GO:0035418//protein localization to synapse;GO:0035641//locomotory exploration behavior;GO:0035865//cellular response to potassium ion;GO:0043113//receptor clustering;GO:0045184//establishment of protein localization;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0050806//positive regulation of synaptic transmission;GO:0050885//neuromuscular process controlling balance;GO:0060997//dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0065003//protein-containing complex assembly;GO:0071625//vocalization behavior;GO:0097061//dendritic spine organization;GO:0097113//AMPA glutamate receptor clustering;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099562//maintenance of postsynaptic density structure;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0150012//positive regulation of neuron projection arborization;GO:1904719//positive regulation of AMPA glutamate receptor clustering;GO:2000310//regulation of NMDA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000821//regulation of grooming behavior	--
ENSG00000132541	11.318	10.887	12.367	12.068	10.477	12.938	227	223	186	177	178	190	RIDA	reactive intermediate imine deaminase A homolog [Source:HGNC Symbol;Acc:HGNC:16897]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0019239//deaminase activity;GO:0036041//long-chain fatty acid binding;GO:0042802//identical protein binding;GO:0043167//ion binding;GO:0046914//transition metal ion binding;GO:0120241//2-iminobutanoate/2-iminopropanoate deaminase;GO:0120242//2-iminobutanoate deaminase activity;GO:0120243//2-iminopropanoate deaminase activity"	"GO:0001822//kidney development;GO:0006402//mRNA catabolic process;GO:0006629//lipid metabolic process;GO:0007420//brain development;GO:0017148//negative regulation of translation;GO:0019518//L-threonine catabolic process to glycine;GO:0030324//lung development;GO:0033993//response to lipid;GO:0050680//negative regulation of epithelial cell proliferation;GO:0061157//mRNA destabilization;GO:0070314//G1 to G0 transition;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1901565//organonitrogen compound catabolic process;GO:1902074//response to salt"	--
ENSG00000132549	4.647	3.086	3.293	2.482	2.773	2.89	1318	894	704	527	684	606	VPS13B	vacuolar protein sorting 13 homolog B [Source:HGNC Symbol;Acc:HGNC:2183]	-	-	-	-	-	-	GO:0015031//protein transport	--
ENSG00000132554	0.308	0.205	0.657	0.425	0.176	0.017	27	17	15	14	9	1	RGS22	regulator of G protein signaling 22 [Source:HGNC Symbol;Acc:HGNC:24499]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0001965//G-protein alpha-subunit binding	GO:0009966//regulation of signal transduction;GO:0009968//negative regulation of signal transduction	--
ENSG00000132561	58.087	59.761	51.41	43.055	47.578	46.718	4035	4120	2548	2139	2780	2350	MATN2	matrilin 2 [Source:HGNC Symbol;Acc:HGNC:6908]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0120216//matrilin complex	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0008150//biological_process;GO:0030198//extracellular matrix organization	--
ENSG00000132563	16.514	18.686	17.515	15.133	16.154	17.463	703	766	563	470	550	529	REEP2	receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:17975]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031883//taste receptor binding	GO:0032386//regulation of intracellular transport;GO:0032596//protein transport into membrane raft;GO:0050913//sensory perception of bitter taste;GO:0050916//sensory perception of sweet taste;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000132570	2.124	2.911	2.355	1.987	2.601	2.61	126	164.5	104	93	123	106	PCBD2	pterin-4 alpha-carbinolamine dehydratase 2 [Source:HGNC Symbol;Acc:HGNC:24474]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K01724;K01724	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005515//protein binding;GO:0008124//4-alpha-hydroxytetrahydrobiopterin dehydratase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding	"GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0019293//tyrosine biosynthetic process, by oxidation of phenylalanine;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000132581	24.072	27.377	29.771	27.088	28.171	31.542	652	686	597	536	617	603	SDF2	stromal cell derived factor 2 [Source:HGNC Symbol;Acc:HGNC:10675]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0101031//chaperone complex	GO:0051787//misfolded protein binding	GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000132589	49.161	50.369	53.365	62.325	57.465	56.829	2698	2771	2163	2507	2653	2245	FLOT2	flotillin 2 [Source:HGNC Symbol;Acc:HGNC:3758]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K07192	GO:0001931//uropod;GO:0002080//acrosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016600//flotillin complex;GO:0030027//lamellipodium;GO:0030139//endocytic vesicle;GO:0030864//cortical actin cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032839//dendrite cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0044291//cell-cell contact zone;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0010629//negative regulation of gene expression;GO:0044860//protein localization to plasma membrane raft;GO:0045661//regulation of myoblast differentiation;GO:0050821//protein stabilization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0072659//protein localization to plasma membrane;GO:0098937//anterograde dendritic transport;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:1902992//negative regulation of amyloid precursor protein catabolic process;GO:1903905//positive regulation of establishment of T cell polarity	--
ENSG00000132591	21.772	23.594	23.65	24.979	23.448	23.902	818	890	667	703	744	647	ERAL1	Era like 12S mitochondrial rRNA chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3424]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019843//rRNA binding;GO:0043024//ribosomal small subunit binding	GO:0000028//ribosomal small subunit assembly;GO:0042254//ribosome biogenesis	--
ENSG00000132600	25.619	24.894	28.728	27.534	29.032	29.537	1019.35	1096	844.64	1046.11	1013.75	879.48	PRMT7	protein arginine methyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:25557]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016277//[myelin basic protein]-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0042393//histone binding;GO:0043021//ribonucleoprotein complex binding;GO:0044020//histone methyltransferase activity (H4-R3 specific)	"GO:0000387//spliceosomal snRNP assembly;GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006479//protein methylation;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0030154//cell differentiation;GO:0032259//methylation;GO:0034969//histone arginine methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0035247//peptidyl-arginine omega-N-methylation;GO:0043046//DNA methylation involved in gamete generation;GO:0043393//regulation of protein binding;GO:0043985//histone H4-R3 methylation"	--
ENSG00000132603	8.645	8.892	7.97	8.387	8.287	9.601	362	361	240	256	294	287	NIP7	nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0042254//ribosome biogenesis;GO:0042255//ribosome assembly;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000132604	11.461	12.172	11.833	10.678	12.005	11.852	614	613	429	394	472	447	TERF2	telomeric repeat binding factor 2 [Source:HGNC Symbol;Acc:HGNC:11729]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0043229//intracellular organelle;GO:0070187//shelterin complex;GO:1904115//axon cytoplasm"	GO:0003677//DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003720//telomerase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0042162//telomeric DNA binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0098505//G-rich strand telomeric DNA binding	"GO:0000723//telomere maintenance;GO:0001701//in utero embryonic development;GO:0006278//RNA-dependent DNA biosynthetic process;GO:0007049//cell cycle;GO:0008089//anterograde axonal transport;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016233//telomere capping;GO:0031627//telomeric loop formation;GO:0031848//protection from non-homologous end joining at telomere;GO:0032204//regulation of telomere maintenance;GO:0032205//negative regulation of telomere maintenance;GO:0032206//positive regulation of telomere maintenance;GO:0032208//negative regulation of telomere maintenance via recombination;GO:0032210//regulation of telomere maintenance via telomerase;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032214//negative regulation of telomere maintenance via semi-conservative replication;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0061820//telomeric D-loop disassembly;GO:0070198//protein localization to chromosome, telomeric region;GO:0090398//cellular senescence;GO:0099087//anterograde axonal transport of messenger ribonucleoprotein complex;GO:1903770//negative regulation of beta-galactosidase activity;GO:1903824//negative regulation of telomere single strand break repair;GO:1904354//negative regulation of telomere capping;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904430//negative regulation of t-circle formation;GO:1905778//negative regulation of exonuclease activity;GO:1905839//negative regulation of telomeric D-loop disassembly;GO:2000773//negative regulation of cellular senescence"	MYB
ENSG00000132612	25.317	24.99	28.26	26	27.381	26.837	2156.17	2139.25	1777.56	1640.21	1970.12	1663.05	VPS4A	vacuolar protein sorting 4 homolog A [Source:HGNC Symbol;Acc:HGNC:13488]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12196;K12196	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005774//vacuolar membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0090543//Flemming body;GO:1904949//ATPase complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019904//protein domain specific binding;GO:0044877//protein-containing complex binding;GO:0140545//protein disaggregase activity	GO:0000916//actomyosin contractile ring contraction;GO:0001778//plasma membrane repair;GO:0006622//protein targeting to lysosome;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0006998//nuclear envelope organization;GO:0007033//vacuole organization;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0007084//mitotic nuclear membrane reassembly;GO:0009838//abscission;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0031468//nuclear membrane reassembly;GO:0032367//intracellular cholesterol transport;GO:0032466//negative regulation of cytokinesis;GO:0032880//regulation of protein localization;GO:0034058//endosomal vesicle fusion;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0044878//mitotic cytokinesis checkpoint signaling;GO:0046761//viral budding from plasma membrane;GO:0051301//cell division;GO:0060548//negative regulation of cell death;GO:0061640//cytoskeleton-dependent cytokinesis;GO:0061738//late endosomal microautophagy;GO:0061764//late endosome to lysosome transport via multivesicular body sorting pathway;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0072319//vesicle uncoating;GO:0090148//membrane fission;GO:0090611//ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway;GO:0097352//autophagosome maturation;GO:1903076//regulation of protein localization to plasma membrane;GO:1903543//positive regulation of exosomal secretion;GO:1903774//positive regulation of viral budding via host ESCRT complex;GO:1904896//ESCRT complex disassembly;GO:1904903//ESCRT III complex disassembly	--
ENSG00000132613	113.545	109.179	141.245	130.688	117.443	174.429	6622	6059	5695	5777	5851	6955	MTSS2	MTSS I-BAR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25094]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030864//cortical actin cytoskeleton;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	"GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0031267//small GTPase binding"	GO:0007009//plasma membrane organization;GO:0030031//cell projection assembly;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0061024//membrane organization;GO:0090630//activation of GTPase activity;GO:0097178//ruffle assembly;GO:0097581//lamellipodium organization	--
ENSG00000132622	0.064	0.048	0.043	0	0.038	0.088	4	3	2	0	2	4	HSPA12B	heat shock protein family A (Hsp70) member 12B [Source:HGNC Symbol;Acc:HGNC:16193]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000132623	1.813	1.913	1.865	1.403	1.569	1.433	200	212	152	115	146	115	ANKEF1	ankyrin repeat and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15803]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000132631	0	0	0	0	0	0	0	0	0	0	0	0	SCP2D1	SCP2 sterol binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16211]	-	-	-	-	-	GO:0032934//sterol binding	GO:0006694//steroid biosynthetic process;GO:0015914//phospholipid transport;GO:0032385//positive regulation of intracellular cholesterol transport	--
ENSG00000132635	16.07	19.063	19.316	24.117	19.334	21.973	585	696	526	632	612	567	PCED1A	PC-esterase domain containing 1A [Source:HGNC Symbol;Acc:HGNC:16212]	-	-	-	-	-	GO:0005515//protein binding;GO:0016740//transferase activity	-	--
ENSG00000132639	0.423	0.211	0.223	0.413	0.306	0.466	18	9	7	13	11	15	SNAP25	synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04911//Insulin secretion;ko04721//Synaptic vesicle cycle	K18211;K18211	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0031083//BLOC-1 complex;GO:0031201//SNARE complex;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031982//vesicle;GO:0035579//specific granule membrane;GO:0036477//somatodendritic compartment;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0070821//tertiary granule membrane;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000149//SNARE binding;GO:0005249//voltage-gated potassium channel activity;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0048306//calcium-dependent protein binding	GO:0001504//neurotransmitter uptake;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0010975//regulation of neuron projection development;GO:0016079//synaptic vesicle exocytosis;GO:0016081//synaptic vesicle docking;GO:0016082//synaptic vesicle priming;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0050796//regulation of insulin secretion;GO:0060291//long-term synaptic potentiation;GO:0070201//regulation of establishment of protein localization;GO:0071805//potassium ion transmembrane transport;GO:0098967//exocytic insertion of neurotransmitter receptor to postsynaptic membrane;GO:0099590//neurotransmitter receptor internalization	--
ENSG00000132640	10.595	8.815	10.282	9.613	10.226	11.652	959	838	648	632	779	815	BTBD3	BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15854]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0048813//dendrite morphogenesis	--
ENSG00000132646	25.244	22.844	26.429	20.965	19.483	21.955	682	619	528	420	444	434	PCNA	proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729]	Cellular Processes;Human Diseases;Cellular Processes;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Cellular community - eukaryotes;Infectious disease: viral;Cell growth and death;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko04530//Tight junction;ko05161//Hepatitis B;ko04110//Cell cycle;ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K04802;K04802;K04802;K04802;K04802;K04802;K04802	"GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005813//centrosome;GO:0016604//nuclear body;GO:0030894//replisome;GO:0043596//nuclear replication fork;GO:0043626//PCNA complex;GO:0070062//extracellular exosome;GO:0070557//PCNA-p21 complex"	GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0030331//estrogen receptor binding;GO:0030337//DNA polymerase processivity factor activity;GO:0030971//receptor tyrosine kinase binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0032405//MutLalpha complex binding;GO:0035035//histone acetyltransferase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0070182//DNA polymerase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006272//leading strand elongation;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007507//heart development;GO:0019985//translesion synthesis;GO:0030855//epithelial cell differentiation;GO:0031297//replication fork processing;GO:0032077//positive regulation of deoxyribonuclease activity;GO:0032355//response to estradiol;GO:0033993//response to lipid;GO:0034644//cellular response to UV;GO:0044849//estrous cycle;GO:0045739//positive regulation of DNA repair;GO:0045740//positive regulation of DNA replication;GO:0046686//response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide;GO:0071466//cellular response to xenobiotic stimulus;GO:0071548//response to dexamethasone;GO:0097421//liver regeneration;GO:1900264//positive regulation of DNA-directed DNA polymerase activity;GO:1902065//response to L-glutamate;GO:1902990//mitotic telomere maintenance via semi-conservative replication"	--
ENSG00000132661	7.354	8.491	7.253	8.212	8.651	10.731	162	188	118	134	161	172	NXT1	nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14285;K14285;K14285;K14285;K14285	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0042272//nuclear RNA export factor complex;GO:0044613//nuclear pore central transport channel	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport	--
ENSG00000132664	4.226	3.159	3.573	3.924	3.229	4.118	189	142	118	130	122	134	POLR3F	RNA polymerase III subunit F [Source:HGNC Symbol;Acc:HGNC:15763]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03025;K03025	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0006359//regulation of transcription by RNA polymerase III;GO:0006383//transcription by RNA polymerase III;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus	--
ENSG00000132669	25.933	26.911	26.711	22.087	26.167	27.195	2024	2033	1497	1308	1623	1443	RIN2	Ras and Rab interactor 2 [Source:HGNC Symbol;Acc:HGNC:18750]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030139//endocytic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0030695//GTPase regulator activity;GO:0031267//small GTPase binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:1904906//positive regulation of endothelial cell-matrix adhesion via fibronectin;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000132670	45.639	48.935	49.968	44.142	43.303	44.899	2850	3110	2237	1941	2281	1882	PTPRA	protein tyrosine phosphatase receptor type A [Source:HGNC Symbol;Acc:HGNC:9664]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043235//receptor complex;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0099699//integral component of synaptic membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007229//integrin-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0050804//modulation of chemical synaptic transmission;GO:0051893//regulation of focal adhesion assembly	--
ENSG00000132671	0.012	0	0	0.017	0.044	0	1	0	0	1	3	0	SSTR4	somatostatin receptor 4 [Source:HGNC Symbol;Acc:HGNC:11333]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04220	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004994//somatostatin receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0016477//cell migration;GO:0030900//forebrain development;GO:0038170//somatostatin signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071385//cellular response to glucocorticoid stimulus;GO:0090238//positive regulation of arachidonic acid secretion;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway"	--
ENSG00000132676	29.172	32.505	30.851	29.861	29.898	29.941	1060	1143	818	777	871	737	DAP3	death associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006915//apoptotic process;GO:0032543//mitochondrial translation;GO:0097190//apoptotic signaling pathway	--
ENSG00000132677	0	0	0	0	0	0	0	0	0	0	0	0	RHBG	Rh family B glycoprotein [Source:HGNC Symbol;Acc:HGNC:14572]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014731//spectrin-associated cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0046658//anchored component of plasma membrane	GO:0008519//ammonium transmembrane transporter activity;GO:0030506//ankyrin binding	GO:0015696//ammonium transport;GO:0070634//transepithelial ammonium transport;GO:0072488//ammonium transmembrane transport	--
ENSG00000132680	8.833	9.052	10.275	9.405	9.464	10.903	558	564	425	429	453	497	KHDC4	"KH domain containing 4, pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:29145]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000132681	0	0	0	0	0	0	0	0	0	0	0	0	ATP1A4	ATPase Na+/K+ transporting subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:14073]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0097225//sperm midpiece;GO:0097733//photoreceptor cell cilium;GO:0120200//rod photoreceptor outer segment	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0019900//kinase binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0030007//cellular potassium ion homeostasis;GO:0030317//flagellated sperm motility;GO:0030641//regulation of cellular pH;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1902600//proton transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000132688	1.429	1.447	1.055	0.269	0.369	0.131	165	168	90	23	36	11	NES	nestin [Source:HGNC Symbol;Acc:HGNC:7756]	-	-	-	-	GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0045111//intermediate filament cytoskeleton	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0019215//intermediate filament binding;GO:0031730//CCR5 chemokine receptor binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0030844//positive regulation of intermediate filament depolymerization;GO:0031076//embryonic camera-type eye development;GO:0032091//negative regulation of protein binding;GO:0043086//negative regulation of catalytic activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0048858//cell projection morphogenesis;GO:0072089//stem cell proliferation;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000132692	11.394	9.439	14.981	14.197	11.639	15.108	631	562	674	556	581	655	BCAN	brevican [Source:HGNC Symbol;Acc:HGNC:23059]	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0030246//carbohydrate binding	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0021766//hippocampus development;GO:0060074//synapse maturation	--
ENSG00000132693	0	0	0	0	0	0	0	0	0	0	0	0	CRP	C-reactive protein [Source:HGNC Symbol;Acc:HGNC:2367]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001849//complement component C1q complex binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0033265//choline binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050750//low-density lipoprotein particle receptor binding	"GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0006958//complement activation, classical pathway;GO:0008228//opsonization;GO:0010628//positive regulation of gene expression;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0032677//regulation of interleukin-8 production;GO:0032930//positive regulation of superoxide anion generation;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0042310//vasoconstriction;GO:0044793//negative regulation by host of viral process;GO:0045087//innate immune response;GO:0050830//defense response to Gram-positive bacterium"	--
ENSG00000132694	9.965	9.681	11.004	9.43	9.959	11.089	1376	1320	1115	972	1145	1121	ARHGEF11	Rho guanine nucleotide exchange factor 11 [Source:HGNC Symbol;Acc:HGNC:14580]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Circulatory system;Endocrine system	"ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05163//Human cytomegalovirus infection;ko04270//Vascular smooth muscle contraction;ko04928//Parathyroid hormone synthesis, secretion and action"	K12331;K12331;K12331;K12331;K12331	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0001664//G protein-coupled receptor binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0001558//regulation of cell growth;GO:0006941//striated muscle contraction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0030010//establishment of cell polarity;GO:0030036//actin cytoskeleton organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction"	--
ENSG00000132698	0	0	0	0	0.208	0	0	0	0	0	4	0	RAB25	"RAB25, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18238]"	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031143//pseudopodium;GO:0031260//pseudopodium membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031489//myosin V binding	GO:0003382//epithelial cell morphogenesis;GO:0006887//exocytosis;GO:0008284//positive regulation of cell population proliferation;GO:0010634//positive regulation of epithelial cell migration;GO:0015031//protein transport;GO:0031268//pseudopodium organization;GO:0060627//regulation of vesicle-mediated transport	--
ENSG00000132702	0	0	0	0	0.065	0	0	0	0	0	1	0	HAPLN2	hyaluronan and proteoglycan link protein 2 [Source:HGNC Symbol;Acc:HGNC:17410]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0005540//hyaluronic acid binding	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0008065//establishment of blood-nerve barrier;GO:0085029//extracellular matrix assembly	--
ENSG00000132703	0	0	0	0	0	0	0	0	0	0	0	0	APCS	"amyloid P component, serum [Source:HGNC Symbol;Acc:HGNC:584]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001849//complement component C1q complex binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0046790//virion binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	"GO:0002674//negative regulation of acute inflammatory response;GO:0006457//protein folding;GO:0006953//acute-phase response;GO:0006958//complement activation, classical pathway;GO:0044793//negative regulation by host of viral process;GO:0044869//negative regulation by host of viral exo-alpha-sialidase activity;GO:0044871//negative regulation by host of viral glycoprotein metabolic process;GO:0045087//innate immune response;GO:0045656//negative regulation of monocyte differentiation;GO:0046597//negative regulation of viral entry into host cell;GO:0048525//negative regulation of viral process;GO:0051131//chaperone-mediated protein complex assembly;GO:0061045//negative regulation of wound healing;GO:1903016//negative regulation of exo-alpha-sialidase activity;GO:1903019//negative regulation of glycoprotein metabolic process"	--
ENSG00000132704	0	0	0	0	0	0	0	0	0	0	0	0	FCRL2	Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0035591//signaling adaptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling	--
ENSG00000132716	31.912	28.036	31.64	27.864	28.767	28.073	1951.44	1725.25	1387.5	1251.76	1434.42	1317.58	DCAF8	DDB1 and CUL4 associated factor 8 [Source:HGNC Symbol;Acc:HGNC:24891]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000132718	28.441	26.278	26.794	21.515	21.815	22.696	3057	2839	2127	1713	1981	1775	SYT11	synaptotagmin 11 [Source:HGNC Symbol;Acc:HGNC:19239]	-	-	-	-	GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032009//early phagosome;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0048787//presynaptic active zone membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0060076//excitatory synapse;GO:0060077//inhibitory synapse;GO:0070382//exocytic vesicle;GO:0098793//presynapse	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0031369//translation initiation factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding	GO:0001778//plasma membrane repair;GO:0001818//negative regulation of cytokine production;GO:0006906//vesicle fusion;GO:0006914//autophagy;GO:0007612//learning;GO:0007613//memory;GO:0009611//response to wounding;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033602//negative regulation of dopamine secretion;GO:0045806//negative regulation of endocytosis;GO:0046929//negative regulation of neurotransmitter secretion;GO:0050765//negative regulation of phagocytosis;GO:0051650//establishment of vesicle localization;GO:0071277//cellular response to calcium ion;GO:1900424//regulation of defense response to bacterium;GO:1903979//negative regulation of microglial cell activation;GO:1905162//regulation of phagosome maturation;GO:1905171//positive regulation of protein localization to phagocytic vesicle;GO:1990927//calcium ion regulated lysosome exocytosis	--
ENSG00000132740	3.141	2.978	3.592	2.953	3.259	4.151	234	224	176	171	215	193	IGHMBP2	immunoglobulin mu DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:5542]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:1990904//ribonucleoprotein complex	"GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008134//transcription factor binding;GO:0008186//ATP-dependent activity, acting on RNA;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0032574//5'-3' RNA helicase activity;GO:0036121//double-stranded DNA helicase activity;GO:0042802//identical protein binding;GO:0043022//ribosome binding;GO:0043139//5'-3' DNA helicase activity;GO:0046872//metal ion binding"	GO:0010501//RNA secondary structure unwinding;GO:0032508//DNA duplex unwinding	--
ENSG00000132744	0	0	0	0	0	0	0	0	0	0	0	0	ACY3	aminoacylase 3 [Source:HGNC Symbol;Acc:HGNC:24104]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	"GO:0003674//molecular_function;GO:0004046//aminoacylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0008150//biological_process	--
ENSG00000132746	0	0	0	0	0.268	0	0	0	0	0	7	0	ALDH3B2	aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Xenobiotics biodegradation and metabolism;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00982//Drug metabolism - cytochrome P450;ko00350//Tyrosine metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism;ko00360//Phenylalanine metabolism	K00129;K00129;K00129;K00129;K00129;K00129;K00129;K00129	GO:0005737//cytoplasm;GO:0005811//lipid droplet	"GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"	GO:0006066//alcohol metabolic process;GO:0006068//ethanol catabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0030148//sphingolipid biosynthetic process	--
ENSG00000132749	1.635	1.38	1.685	1.822	2.032	2.235	99	88	75	86	91	97	TESMIN	testis expressed metallothionein like protein [Source:HGNC Symbol;Acc:HGNC:7446]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006875//cellular metal ion homeostasis;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0010038//response to metal ion;GO:0030154//cell differentiation"	--
ENSG00000132763	3.1	3.333	2.847	2.967	4.32	3.411	200.15	216.53	170.08	145.71	206.01	153.35	MMACHC	metabolism of cobalamin associated C [Source:HGNC Symbol;Acc:HGNC:24525]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14618	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0031419//cobalamin binding;GO:0032451//demethylase activity;GO:0033787//cyanocobalamin reductase (cyanide-eliminating) activity;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding;GO:0071949//FAD binding	GO:0006749//glutathione metabolic process;GO:0009235//cobalamin metabolic process;GO:0070988//demethylation	--
ENSG00000132768	4.945	6.273	5.096	6.377	5.99	7.943	252	268	192	219	235	240	DPH2	diphthamide biosynthesis 2 [Source:HGNC Symbol;Acc:HGNC:3004]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0090560//2-(3-amino-3-carboxypropyl)histidine synthase activity	GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine	--
ENSG00000132773	3.398	3.533	3.667	2.897	3.266	3.441	133	139	106	84	108	98	TOE1	"target of EGR1, exonuclease [Source:HGNC Symbol;Acc:HGNC:15954]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0016607//nuclear speck	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0046872//metal ion binding	"GO:0034472//snRNA 3'-end processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000132780	26.537	21.89	23.161	22.317	21.574	23.489	942	796	625	616	674	601	NASP	nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042393//histone binding;GO:0044877//protein-containing complex binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0001824//blastocyst development;GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007049//cell cycle;GO:0008584//male gonad development;GO:0015031//protein transport;GO:0033574//response to testosterone;GO:0034080//CENP-A containing nucleosome assembly;GO:0043486//histone exchange	--
ENSG00000132781	3.155	4.892	2.885	2.759	3.392	4.339	114	130	71.17	73.01	103	99	MUTYH	mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K03575	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	"GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019104//DNA N-glycosylase activity;GO:0032357//oxidized purine DNA binding;GO:0032407//MutSalpha complex binding;GO:0034039//8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0035485//adenine/guanine mispair binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006298//mismatch repair;GO:0006950//response to stress;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0045007//depurination	--
ENSG00000132792	19.019	17.425	19.483	20.233	23.291	19.324	734	684	534	556	726	546	CTNNBL1	catenin beta like 1 [Source:HGNC Symbol;Acc:HGNC:15879]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12864	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0019899//enzyme binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0016445//somatic diversification of immunoglobulins;GO:0043065//positive regulation of apoptotic process"	--
ENSG00000132793	1.176	1.199	1.712	1.616	1.37	1.839	105.34	108.68	112.65	106.24	103.57	120.23	LPIN3	lipin 3 [Source:HGNC Symbol;Acc:HGNC:14451]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine and metabolic disease;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04150//mTOR signaling pathway;ko04936//Alcoholic liver disease;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K15728;K15728;K15728;K15728;K15728	GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane	GO:0003713//transcription coactivator activity;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0016311//dephosphorylation;GO:0019432//triglyceride biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0044255//cellular lipid metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000132801	1.633	1.797	1.999	2.157	2.117	1.886	94	104	85	92	103	79	ZSWIM3	zinc finger SWIM-type containing 3 [Source:HGNC Symbol;Acc:HGNC:16157]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000132819	16.476	15.338	17.404	13.762	15.121	12.5	797	735	613	506	566	451	RBM38	RNA binding motif protein 38 [Source:HGNC Symbol;Acc:HGNC:15818]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	"GO:0006397//mRNA processing;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0010830//regulation of myotube differentiation;GO:0030154//cell differentiation;GO:0043484//regulation of RNA splicing;GO:0051726//regulation of cell cycle;GO:0070935//3'-UTR-mediated mRNA stabilization"	--
ENSG00000132821	12.041	9.411	12.524	19.278	17.009	17.346	359	334	310	452	466	377	VSTM2L	V-set and transmembrane domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:16096]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030424//axon	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0043524//negative regulation of neuron apoptotic process;GO:0070593//dendrite self-avoidance	--
ENSG00000132823	11.114	10.556	10.91	11.513	8.686	10.404	436	408	310	329	282	296	OSER1	oxidative stress responsive serine rich 1 [Source:HGNC Symbol;Acc:HGNC:16105]	-	-	-	-	-	-	GO:0070301//cellular response to hydrogen peroxide	--
ENSG00000132824	16.516	17.29	17.691	15.935	13.795	14.581	1128	1137	814	761	791	684	SERINC3	serine incorporator 3 [Source:HGNC Symbol;Acc:HGNC:11699]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0015194//L-serine transmembrane transporter activity	GO:0002376//immune system process;GO:0006564//L-serine biosynthetic process;GO:0006658//phosphatidylserine metabolic process;GO:0006665//sphingolipid metabolic process;GO:0009597//detection of virus;GO:0015825//L-serine transport;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000132825	2.819	2.436	2.204	3.091	3.164	3.31	213	185	123	173	202	182	PPP1R3D	protein phosphatase 1 regulatory subunit 3D [Source:HGNC Symbol;Acc:HGNC:9294]	Organismal Systems;Human Diseases	Endocrine system;Endocrine and metabolic disease	ko04910//Insulin signaling pathway;ko04931//Insulin resistance	K07189;K07189	GO:0000164//protein phosphatase type 1 complex;GO:0042587//glycogen granule;GO:0043231//intracellular membrane-bounded organelle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019899//enzyme binding;GO:2001069//glycogen binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0005981//regulation of glycogen catabolic process;GO:0006470//protein dephosphorylation	--
ENSG00000132837	0.281	0.209	0.068	0.73	0.182	0.104	17	11	3	12	8	5	DMGDH	dimethylglycine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24475]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism"	K00315;K00315	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0047865//dimethylglycine dehydrogenase activity	GO:0006579//amino-acid betaine catabolic process;GO:0019695//choline metabolic process;GO:0022900//electron transport chain;GO:0042426//choline catabolic process	--
ENSG00000132840	0	0	0	0	0	0	0	0	0	0	0	0	BHMT2	betaine--homocysteine S-methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:1048]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K00547;K00547	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0008168//methyltransferase activity;GO:0008172//S-methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0047150//betaine-homocysteine S-methyltransferase activity;GO:0061627//S-methylmethionine-homocysteine S-methyltransferase activity	GO:0009086//methionine biosynthetic process;GO:0032259//methylation;GO:0033477//S-methylmethionine metabolic process;GO:0046500//S-adenosylmethionine metabolic process;GO:0071267//L-methionine salvage	--
ENSG00000132842	20.733	18.275	15.332	14.087	16.333	16.414	1691	1511	934	856	1124	962	AP3B1	adaptor related protein complex 3 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:566]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12397	GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030123//AP-3 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030742//GTP-dependent protein binding	"GO:0000902//cell morphogenesis;GO:0002224//toll-like receptor signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003016//respiratory system process;GO:0006464//cellular protein modification process;GO:0006622//protein targeting to lysosome;GO:0006882//cellular zinc ion homeostasis;GO:0006886//intracellular protein transport;GO:0006954//inflammatory response;GO:0007040//lysosome organization;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007596//blood coagulation;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016182//synaptic vesicle budding from endosome;GO:0016192//vesicle-mediated transport;GO:0019882//antigen processing and presentation;GO:0030324//lung development;GO:0030851//granulocyte differentiation;GO:0032438//melanosome organization;GO:0034394//protein localization to cell surface;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043473//pigmentation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046907//intracellular transport;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0048490//anterograde synaptic vesicle transport;GO:0048872//homeostasis of number of cells;GO:0050790//regulation of catalytic activity;GO:0051138//positive regulation of NK T cell differentiation;GO:0060155//platelet dense granule organization;GO:0060425//lung morphogenesis;GO:0061024//membrane organization;GO:0090152//establishment of protein localization to mitochondrial membrane involved in mitochondrial fission;GO:0098773//skin epidermis development;GO:1903232//melanosome assembly"	--
ENSG00000132846	13.318	12.214	12.419	12.903	13.341	14.713	1632	1562	1167	1216	1434	1362	ZBED3	zinc finger BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:20711]	-	-	-	-	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0001933//negative regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007015//actin filament organization;GO:0009749//response to glucose;GO:0016055//Wnt signaling pathway;GO:0032868//response to insulin;GO:0040019//positive regulation of embryonic development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0051293//establishment of spindle localization;GO:0051643//endoplasmic reticulum localization;GO:0051646//mitochondrion localization;GO:0090263//positive regulation of canonical Wnt signaling pathway	zf-BED
ENSG00000132849	4.193	3.408	3.465	2.287	2.76	4.013	567	533	367	266	350	314	PATJ	PATJ crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:28881]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K06092;K06092;K06092	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0034451//centriolar satellite;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0031023//microtubule organizing center organization;GO:0035089//establishment of apical/basal cell polarity;GO:0035556//intracellular signal transduction;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0120192//tight junction assembly	--
ENSG00000132854	0.398	0.796	0.838	1.317	1.47	1.362	38	67	47	105	115	103	KANK4	KN motif and ankyrin repeat domains 4 [Source:HGNC Symbol;Acc:HGNC:27263]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding	GO:0030837//negative regulation of actin filament polymerization	--
ENSG00000132855	0	0	0	0	0	0	0	0	0	0	0	0	ANGPTL3	angiopoietin like 3 [Source:HGNC Symbol;Acc:HGNC:491]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22288	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0030027//lamellipodium;GO:0042995//cell projection;GO:0062023//collagen-containing extracellular matrix	GO:0004857//enzyme inhibitor activity;GO:0004859//phospholipase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0001525//angiogenesis;GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006644//phospholipid metabolic process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0008203//cholesterol metabolic process;GO:0009395//phospholipid catabolic process;GO:0009725//response to hormone;GO:0010519//negative regulation of phospholipase activity;GO:0019915//lipid storage;GO:0030335//positive regulation of cell migration;GO:0042632//cholesterol homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0048844//artery morphogenesis;GO:0050996//positive regulation of lipid catabolic process;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0055088//lipid homeostasis;GO:0055090//acylglycerol homeostasis;GO:0055091//phospholipid homeostasis;GO:0070328//triglyceride homeostasis	--
ENSG00000132872	0.024	0.024	0	0	0	0	2	2	0	0	0	0	SYT4	synaptotagmin 4 [Source:HGNC Symbol;Acc:HGNC:11512]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032127//dense core granule membrane;GO:0036477//somatodendritic compartment;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070382//exocytic vesicle;GO:0097449//astrocyte projection;GO:0098978//glutamatergic synapse;GO:0098992//neuronal dense core vesicle;GO:0099012//neuronal dense core vesicle membrane;GO:0099066//integral component of neuronal dense core vesicle membrane;GO:1990742//microvesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0046872//metal ion binding	"GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0007269//neurotransmitter secretion;GO:0007613//memory;GO:0014049//positive regulation of glutamate secretion;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0030100//regulation of endocytosis;GO:0030154//cell differentiation;GO:0031338//regulation of vesicle fusion;GO:0033604//negative regulation of catecholamine secretion;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0048174//negative regulation of short-term neuronal synaptic plasticity;GO:0050709//negative regulation of protein secretion;GO:0071277//cellular response to calcium ion;GO:0099161//regulation of presynaptic dense core granule exocytosis;GO:0099183//trans-synaptic signaling by BDNF, modulating synaptic transmission;GO:0099519//dense core granule cytoskeletal transport;GO:1903861//positive regulation of dendrite extension;GO:1905415//positive regulation of dense core granule exocytosis;GO:1905433//negative regulation of retrograde trans-synaptic signaling by neuropeptide;GO:2000301//negative regulation of synaptic vesicle exocytosis"	--
ENSG00000132874	0	0	0.038	0	0	0	0	0	1	0	0	0	SLC14A2	solute carrier family 14 member 2 [Source:HGNC Symbol;Acc:HGNC:10919]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0050839//cell adhesion molecule binding	GO:0015840//urea transport;GO:0055085//transmembrane transport;GO:0071918//urea transmembrane transport	--
ENSG00000132879	19.052	22.766	26.176	26.923	25.343	32.043	687	792	618	658	690	765	FBXO44	F-box protein 44 [Source:HGNC Symbol;Acc:HGNC:24847]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006516//glycoprotein catabolic process;GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000132881	4.02	3.765	2.662	1.819	2.32	1.979	97	77	41	44	64	47	CPLANE2	ciliogenesis and planar polarity effector 2 [Source:HGNC Symbol;Acc:HGNC:28127]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006887//exocytosis;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0030030//cell projection organization;GO:0031338//regulation of vesicle fusion;GO:0034613//cellular protein localization;GO:0060271//cilium assembly	--
ENSG00000132906	5.868	7.069	4.254	5.113	6.832	5.427	237	268	153	171	236	174	CASP9	caspase 9 [Source:HGNC Symbol;Acc:HGNC:1511]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Cardiovascular disease;Endocrine system;Infectious disease: parasitic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04210//Apoptosis;ko05416//Viral myocarditis;ko04919//Thyroid hormone signaling pathway;ko05145//Toxoplasmosis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399;K04399	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0008303//caspase complex;GO:0032991//protein-containing complex;GO:0043293//apoptosome	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0001822//kidney development;GO:0002931//response to ischemia;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007568//aging;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0009411//response to UV;GO:0014070//response to organic cyclic compound;GO:0030220//platelet formation;GO:0032025//response to cobalt ion;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0034349//glial cell apoptotic process;GO:0034644//cellular response to UV;GO:0042770//signal transduction in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0046677//response to antibiotic;GO:0071407//cellular response to organic cyclic compound;GO:0071549//cellular response to dexamethasone stimulus;GO:0071887//leukocyte apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:0097202//activation of cysteine-type endopeptidase activity;GO:2001020//regulation of response to DNA damage stimulus	--
ENSG00000132911	0	0	0	0	0	0	0	0	0	0	0	0	NMUR2	neuromedin U receptor 2 [Source:HGNC Symbol;Acc:HGNC:16454]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05053	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001607//neuromedin U receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008188//neuropeptide receptor activity;GO:0042924//neuromedin U binding	GO:0002023//reduction of food intake in response to dietary excess;GO:0006816//calcium ion transport;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007417//central nervous system development;GO:0007625//grooming behavior;GO:0007631//feeding behavior;GO:0015698//inorganic anion transport;GO:0019722//calcium-mediated signaling;GO:0043006//activation of phospholipase A2 activity by calcium-mediated signaling;GO:0048016//inositol phosphate-mediated signaling;GO:0048265//response to pain;GO:0050482//arachidonic acid secretion;GO:0051930//regulation of sensory perception of pain	--
ENSG00000132912	25.642	24.613	26.132	22.725	22.676	25.887	2082	2003	1537	1331	1512	1422	DCTN4	dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10426;K10426;K10426;K10426;K10426	GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005869//dynactin complex;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0030017//sarcomere	GO:0005515//protein binding;GO:0047485//protein N-terminus binding	-	--
ENSG00000132915	0	0.009	0.024	0	0	0.049	0	1	2	0	0	4	PDE6A	phosphodiesterase 6A [Source:HGNC Symbol;Acc:HGNC:8785]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04744//Phototransduction	K08718;K08718;K08718	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042622//photoreceptor outer segment membrane;GO:0097381//photoreceptor disc membrane	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye	--
ENSG00000132932	0.105	0.05	0.052	0.07	0.06	0.08	19	9	7	6	9	6	ATP8A2	ATPase phospholipid transporting 8A2 [Source:HGNC Symbol;Acc:HGNC:13533]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015247//aminophospholipid flippase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090555//phosphatidylethanolamine flippase activity;GO:0090556//phosphatidylserine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140346//phosphatidylserine flippase activity	GO:0003011//involuntary skeletal muscle contraction;GO:0006869//lipid transport;GO:0007409//axonogenesis;GO:0007568//aging;GO:0008285//negative regulation of cell population proliferation;GO:0010842//retina layer formation;GO:0010976//positive regulation of neuron projection development;GO:0010996//response to auditory stimulus;GO:0015914//phospholipid transport;GO:0034204//lipid translocation;GO:0040018//positive regulation of multicellular organism growth;GO:0042472//inner ear morphogenesis;GO:0042755//eating behavior;GO:0043588//skin development;GO:0045332//phospholipid translocation;GO:0048666//neuron development;GO:0050884//neuromuscular process controlling posture;GO:0050908//detection of light stimulus involved in visual perception;GO:0060052//neurofilament cytoskeleton organization;GO:0061092//positive regulation of phospholipid translocation;GO:0140331//aminophospholipid translocation	--
ENSG00000132938	5.985	5.972	5.802	3.823	3.874	3.7	764	781	507	370	454	338	MTUS2	microtubule associated scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:20595]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity	-	--
ENSG00000132950	4.499	2.967	3.049	3.163	2.54	3.071	235	187	143	123	134	129	ZMYM5	zinc finger MYM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13029]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000132952	3.675	2.842	3.161	2.101	2.647	2.672	371	290	237	158	227	196	USPL1	ubiquitin specific peptidase like 1 [Source:HGNC Symbol;Acc:HGNC:20294]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0015030//Cajal body	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0032183//SUMO binding;GO:0070140//SUMO-specific isopeptidase activity	GO:0006508//proteolysis;GO:0008283//cell population proliferation;GO:0009301//snRNA transcription;GO:0016926//protein desumoylation;GO:0030576//Cajal body organization	--
ENSG00000132953	6.5	6.219	5.536	5.269	5.413	6.077	1329	1278	836	798	935	904	XPO4	exportin 4 [Source:HGNC Symbol;Acc:HGNC:17796]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K25203	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding	GO:0006611//protein export from nucleus;GO:0015031//protein transport;GO:0046827//positive regulation of protein export from nucleus;GO:0051169//nuclear transport	--
ENSG00000132958	0	0	0	0	0	0	0	0	0	0	0	0	TPTE2	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	"GO:0004725//protein tyrosine phosphatase activity;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0051800//phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008285//negative regulation of cell population proliferation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048870//cell motility;GO:0051896//regulation of protein kinase B signaling	--
ENSG00000132963	23.097	22.937	21.954	20.041	21.275	20.94	641	640	450	412	499	423	POMP	proteasome maturation protein [Source:HGNC Symbol;Acc:HGNC:20330]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K11599	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0043248//proteasome assembly	--
ENSG00000132964	6.882	5.204	5.712	5.578	4.623	5.152	437	332	268	218	248	238	CDK8	cyclin dependent kinase 8 [Source:HGNC Symbol;Acc:HGNC:1779]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016592//mediator complex;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000132965	0.111	0	0.075	0.075	0.066	0.152	2	0	1	1	1	2	ALOX5AP	arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436]	Organismal Systems	Immune system	ko04664//Fc epsilon RI signaling pathway	K20735	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0004051//arachidonate 5-lipoxygenase activity;GO:0004364//glutathione transferase activity;GO:0004464//leukotriene-C4 synthase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding;GO:0050544//arachidonic acid binding	GO:0002540//leukotriene production involved in inflammatory response;GO:0002675//positive regulation of acute inflammatory response;GO:0006691//leukotriene metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0019372//lipoxygenase pathway;GO:0050790//regulation of catalytic activity;GO:0070207//protein homotrimerization;GO:0071277//cellular response to calcium ion;GO:0098869//cellular oxidant detoxification	--
ENSG00000132970	14.089	12.048	12.162	11.819	11.228	13.34	1152	986	804	726	886	834	WASF3	WASP family member 3 [Source:HGNC Symbol;Acc:HGNC:12734]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Cancer: overview;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko04520//Adherens junction	K06083;K06083;K06083;K06083;K06083	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0071933//Arp2/3 complex binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0014003//oligodendrocyte development;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0031643//positive regulation of myelination;GO:0065003//protein-containing complex assembly;GO:0098885//modification of postsynaptic actin cytoskeleton;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000132972	0	0	0	0	0	0	0	0	0	0	0	0	RNF17	ring finger protein 17 [Source:HGNC Symbol;Acc:HGNC:10060]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation	--
ENSG00000132975	0	0	0	0	0	0	0	0	0	0	0	0	GPR12	G protein-coupled receptor 12 [Source:HGNC Symbol;Acc:HGNC:4466]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0031210//phosphatidylcholine binding	GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process	--
ENSG00000133019	1.002	1.304	0.873	1.261	1.258	0.858	161.33	123.84	79.07	98	101.56	90.22	CHRM3	cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Cell motility;Nervous system;Digestive system;Digestive system;Endocrine system;Sensory system;Digestive system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04725//Cholinergic synapse;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion	K04131;K04131;K04131;K04131;K04131;K04131;K04131;K04131;K04131;K04131;K04131	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0038023//signaling receptor activity;GO:0042166//acetylcholine binding	"GO:0003056//regulation of vascular associated smooth muscle contraction;GO:0006464//cellular protein modification process;GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007399//nervous system development;GO:0019722//calcium-mediated signaling;GO:0032412//regulation of ion transmembrane transporter activity;GO:0045987//positive regulation of smooth muscle contraction;GO:0046541//saliva secretion;GO:0095500//acetylcholine receptor signaling pathway;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000133020	0.04	0.008	0	0.022	0.057	0.022	5	1	0	2	6	2	MYH8	myosin heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:7578]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0032982//myosin filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008307//structural constituent of muscle;GO:0016887//ATP hydrolysis activity;GO:0017018//myosin phosphatase activity;GO:0032027//myosin light chain binding;GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0006470//protein dephosphorylation;GO:0006936//muscle contraction;GO:0030049//muscle filament sliding;GO:0046034//ATP metabolic process	--
ENSG00000133026	47.629	45.607	35.332	28.465	32.481	30.505	7655	7377	4197	3398	4415	3578	MYH10	myosin heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:7568]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Circulatory system	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04530//Tight junction;ko04270//Vascular smooth muscle contraction	K10352;K10352;K10352;K10352	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005938//cell cortex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030027//lamellipodium;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0042641//actomyosin;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0097513//myosin II filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0035613//RNA stem-loop binding;GO:0043531//ADP binding;GO:0048027//mRNA 5'-UTR binding;GO:0051015//actin filament binding	GO:0000281//mitotic cytokinesis;GO:0007155//cell adhesion;GO:0008360//regulation of cell shape;GO:0030048//actin filament-based movement;GO:0031032//actomyosin structure organization;GO:0050714//positive regulation of protein secretion	--
ENSG00000133027	12.763	12.829	14.453	19.086	17.118	13.825	270	273	226	299	306	213	PEMT	phosphatidylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8830]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K00551;K00551	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000773//phosphatidyl-N-methylethanolamine N-methyltransferase activity;GO:0004608//phosphatidylethanolamine N-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0080101//phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	GO:0001835//blastocyst hatching;GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006686//sphingomyelin biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0032259//methylation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000133028	19.666	20.681	19.76	17.405	16.973	16.52	1042	1111	807	710	817	762	SCO1	synthesis of cytochrome C oxidase 1 [Source:HGNC Symbol;Acc:HGNC:10603]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030016//myofibril;GO:0031305//integral component of mitochondrial inner membrane	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016531//copper chaperone activity;GO:0046872//metal ion binding	GO:0006878//cellular copper ion homeostasis;GO:0008535//respiratory chain complex IV assembly;GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000133030	32.568	31.325	30.46	29.271	30.292	26.082	4412	4182	3188	2866	3539	2760	MPRIP	myosin phosphatase Rho interacting protein [Source:HGNC Symbol;Acc:HGNC:30321]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization	--
ENSG00000133048	28.81	29.542	37.222	21.348	26.099	27.586	1039	1076	991	573	799	723	CHI3L1	chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008061//chitin binding;GO:0030246//carbohydrate binding	GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0009612//response to mechanical stimulus;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0030324//lung development;GO:0032757//positive regulation of interleukin-8 production;GO:0034612//response to tumor necrosis factor;GO:0045766//positive regulation of angiogenesis;GO:0051216//cartilage development;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070555//response to interleukin-1;GO:0070741//response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000133055	0.027	0.026	0.072	0.072	0	0	1	1	2	2	0	0	MYBPH	myosin binding protein H [Source:HGNC Symbol;Acc:HGNC:7552]	-	-	-	-	GO:0032982//myosin filament	GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0006942//regulation of striated muscle contraction;GO:0007155//cell adhesion	--
ENSG00000133056	1.573	1.644	1.781	1.368	1.257	1.437	237	262	196	157	169	153	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [Source:HGNC Symbol;Acc:HGNC:8972]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Infectious disease: bacterial;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05132//Salmonella infection;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00923;K00923;K00923;K00923	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001727//lipid kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0035091//phosphatidylinositol binding;GO:0052742//phosphatidylinositol kinase activity	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008150//biological_process;GO:0009267//cellular response to starvation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016236//macroautophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043491//protein kinase B signaling;GO:0046834//lipid phosphorylation;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:1905037//autophagosome organization	--
ENSG00000133059	10.401	9.654	10.105	9.686	10.148	9.781	1728	1608	1239	1192	1423	1181	DSTYK	dual serine/threonine and tyrosine protein kinase [Source:HGNC Symbol;Acc:HGNC:29043]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000133063	0	0	0	0	0	0	0	0	0	0	0	0	CHIT1	chitinase 1 [Source:HGNC Symbol;Acc:HGNC:1936]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01183;K01183	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004568//chitinase activity;GO:0008061//chitin binding;GO:0008843//endochitinase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0000272//polysaccharide catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process;GO:0006955//immune response;GO:0008152//metabolic process;GO:0009617//response to bacterium;GO:0044245//polysaccharide digestion	--
ENSG00000133065	13.944	14.293	13.701	11.831	13.922	13.656	1451	1495	1053	912	1224	1034	SLC41A1	solute carrier family 41 member 1 [Source:HGNC Symbol;Acc:HGNC:19429]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0061768//magnesium:sodium antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0010961//cellular magnesium ion homeostasis;GO:0015693//magnesium ion transport;GO:0030001//metal ion transport;GO:0035725//sodium ion transmembrane transport;GO:0071286//cellular response to magnesium ion;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000133067	0.185	0.354	0.233	0.704	0.266	0.418	14	26	13	26	17	23	LGR6	leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K08399	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0032588//trans-Golgi network membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016500//protein-hormone receptor activity;GO:0048495//Roundabout binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007411//axon guidance;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030335//positive regulation of cell migration;GO:0042246//tissue regeneration;GO:0050919//negative chemotaxis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1990523//bone regeneration	--
ENSG00000133069	25.272	22.73	27.079	19.08	20.006	27.76	1667	1526	1346	954	1168	1393	TMCC2	transmembrane and coiled-coil domain family 2 [Source:HGNC Symbol;Acc:HGNC:24239]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0042982//amyloid precursor protein metabolic process	--
ENSG00000133083	0.951	0.392	0.831	0.371	0.595	0.447	73	42	45	25	50	32	DCLK1	doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0009615//response to virus;GO:0016197//endosomal transport;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0021952//central nervous system projection neuron axonogenesis;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0035556//intracellular signal transduction;GO:0048675//axon extension;GO:0048812//neuron projection morphogenesis;GO:0048813//dendrite morphogenesis;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000133101	0.227	0.471	0.499	0.345	0.067	0.23	8	17	13	9	2	6	CCNA1	cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Cell growth and death;Signal transduction;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04110//Cell cycle;ko04152//AMPK signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko05221//Acute myeloid leukemia	K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0097123//cyclin A1-CDK2 complex;GO:0097124//cyclin A2-CDK2 complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007049//cell cycle;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division	--
ENSG00000133103	9.42	8.022	57.998	4.734	6.019	29.089	703	599	374	261	377	340	COG6	component of oligomeric golgi complex 6 [Source:HGNC Symbol;Acc:HGNC:18621]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0070085//glycosylation"	--
ENSG00000133104	38.476	36.109	34.62	28.071	28.997	33.648	2688	2492	1779	1438	1680	1686	SPART	spartin [Source:HGNC Symbol;Acc:HGNC:18514]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K19366	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0045202//synapse	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0009838//abscission;GO:0030514//negative regulation of BMP signaling pathway;GO:0034389//lipid droplet organization;GO:0048698//negative regulation of collateral sprouting in absence of injury;GO:0050905//neuromuscular process;GO:0051301//cell division;GO:0051881//regulation of mitochondrial membrane potential;GO:0060612//adipose tissue development	--
ENSG00000133105	0	0	0	0	0	0	0	0	0	0	0	0	RXFP2	relaxin family peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:17318]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K04307;K04307	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0008584//male gonad development;GO:0009755//hormone-mediated signaling pathway	--
ENSG00000133106	0.831	1.486	0.483	2.036	1.75	1.939	39	62	23	74	65	68	EPSTI1	epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000133107	8.121	6.653	7.515	6.376	6.165	8.112	756	608	510	388	463	516	TRPC4	transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336]	Organismal Systems;Organismal Systems	Development and regeneration;Endocrine system	ko04360//Axon guidance;ko04929//GnRH secretion	K04967;K04967	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030863//cortical cytoskeleton;GO:0032991//protein-containing complex;GO:0034703//cation channel complex;GO:0034704//calcium channel complex;GO:0045121//membrane raft	"GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0015279//store-operated calcium channel activity;GO:0045296//cadherin binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0014051//gamma-aminobutyric acid secretion;GO:0048709//oligodendrocyte differentiation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport	--
ENSG00000133110	1.008	1.73	0.686	0.801	1.924	0.693	68	114	34	40	108	33	POSTN	periostin [Source:HGNC Symbol;Acc:HGNC:16953]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0007155//cell adhesion;GO:0008593//regulation of Notch signaling pathway;GO:0009888//tissue development;GO:0030198//extracellular matrix organization;GO:0071307//cellular response to vitamin K	--
ENSG00000133111	1.819	1.456	1.812	1.157	1.93	1.724	87	70	64	41	78	60	RFXAP	regulatory factor X associated protein [Source:HGNC Symbol;Acc:HGNC:9988]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune disease;Immune system	ko05152//Tuberculosis;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation	K08063;K08063;K08063	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000133112	2473.445	2491.434	2421.951	2566.391	2183.989	2334.401	54306	55446	39453	41291	41074	37292	TPT1	"tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]"	-	-	-	-	GO:0000922//spindle pole;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005771//multivesicular body;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0009615//response to virus;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	--
ENSG00000133114	4.453	4.277	3.674	3.195	3.903	3.816	362	356	217	198	263	228	GPALPP1	GPALPP motifs containing 1 [Source:HGNC Symbol;Acc:HGNC:20298]	-	-	-	-	-	-	-	--
ENSG00000133115	0.23	0.051	0.035	0.069	0.03	0	9	2	1	2	1	0	STOML3	stomatin like 3 [Source:HGNC Symbol;Acc:HGNC:19420]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008150//biological_process	--
ENSG00000133116	1.346	1.263	1.094	1.324	1.206	1.85	140	132	84	102	106	140	KL	klotho [Source:HGNC Symbol;Acc:HGNC:6344]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Aging;Excretory system;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko04928//Parathyroid hormone synthesis, secretion and action;ko04211//Longevity regulating pathway;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism"	K14756;K14756;K14756;K14756;K14756;K14756	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004566//beta-glucuronidase activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005179//hormone activity;GO:0005499//vitamin D binding;GO:0008422//beta-glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0017134//fibroblast growth factor binding"	GO:0002526//acute inflammatory response;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0005975//carbohydrate metabolic process;GO:0006112//energy reserve metabolic process;GO:0007568//aging;GO:0008152//metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0014823//response to activity;GO:0030501//positive regulation of bone mineralization;GO:0033280//response to vitamin D;GO:0042421//norepinephrine biosynthetic process;GO:0055074//calcium ion homeostasis;GO:0071774//response to fibroblast growth factor;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:1990776//response to angiotensin	--
ENSG00000133119	4.571	4.303	3.496	4.54	3.787	4.244	209	194	122	142	139	134	RFC3	replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03430//Mismatch repair	K10756;K10756;K10756	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex;GO:0031390//Ctf18 RFC-like complex	"GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0017116//single-stranded DNA helicase activity"	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006281//DNA repair;GO:0032508//DNA duplex unwinding;GO:0046683//response to organophosphorus;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000133121	2.681	2.463	2.472	2.905	2.682	3.002	320	287	224	249	278	268	STARD13	StAR related lipid transfer domain containing 13 [Source:HGNC Symbol;Acc:HGNC:19164]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0043542//endothelial cell migration;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0097498//endothelial tube lumen extension	--
ENSG00000133124	0	0.044	0.03	0.01	0.026	0.02	0	6	3	1	3	2	IRS4	insulin receptor substrate 4 [Source:HGNC Symbol;Acc:HGNC:6128]	Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Signal transduction;Transport and catabolism;Endocrine system;Signal transduction;Signal transduction;Endocrine system;Aging;Endocrine system;Aging;Endocrine system;Endocrine and metabolic disease	"ko05010//Alzheimer disease;ko04022//cGMP-PKG signaling pathway;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04930//Type II diabetes mellitus"	K17446;K17446;K17446;K17446;K17446;K17446;K17446;K17446;K17446;K17446;K17446;K17446	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0043548//phosphatidylinositol 3-kinase binding	GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway	--
ENSG00000133131	7.761	6.721	6.891	5.364	5.135	6.087	530.23	481.1	341.43	282.62	299.45	298.42	MORC4	MORC family CW-type zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:23485]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016887//ATP hydrolysis activity;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	-	--
ENSG00000133134	36.259	33.747	34.471	44.262	37.055	43.011	624	586.82	436.87	564	540	536	BEX2	brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0042981//regulation of apoptotic process;GO:0051726//regulation of cell cycle	--
ENSG00000133135	3.973	3.097	3.726	5.41	5.191	7.304	231	181	160	233	255	309	RNF128	ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153]	-	-	-	-	GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001818//negative regulation of cytokine production;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031647//regulation of protein stability;GO:0061462//protein localization to lysosome;GO:1904352//positive regulation of protein catabolic process in the vacuole	--
ENSG00000133136	0.038	0	0	0	0	0.052	1	0	0	0	0	1	GNG5P2	G protein subunit gamma 5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:24826]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542	GO:0005834//heterotrimeric G-protein complex	GO:0031681//G-protein beta-subunit binding	GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000133138	5.721	3.711	4.112	3.212	3.86	3.829	580.28	388.77	337.66	253.89	319.21	292.52	TBC1D8B	TBC1 domain family member 8B [Source:HGNC Symbol;Acc:HGNC:24715]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0003094//glomerular filtration;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000133142	49.514	54.24	48.421	41.014	42.842	37.241	1222	1370	855	757	833	682	TCEAL4	transcription elongation factor A like 4 [Source:HGNC Symbol;Acc:HGNC:26121]	-	-	-	-	GO:0005634//nucleus	GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0006414//translational elongation	--
ENSG00000133169	6.125	7.19	4.937	8.351	7.322	6.584	101	119.18	60.13	102	102	79	BEX1	brain expressed X-linked 1 [Source:HGNC Symbol;Acc:HGNC:1036]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity	--
ENSG00000133193	9.652	13.038	9.64	9.447	10.918	11.205	514.24	564.47	398.96	337.14	444.85	381.35	FAM104A	family with sequence similarity 104 member A [Source:HGNC Symbol;Acc:HGNC:25918]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000133195	4.373	2.628	3.753	4.885	4.626	2.822	149	140	122	163	149	101	SLC39A11	solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14717;K14717	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport	--
ENSG00000133216	11.39	12.926	10.51	12.327	11.017	11.912	1277	1340	865	971	1137	1001	EPHB2	EPH receptor B2 [Source:HGNC Symbol;Acc:HGNC:3393]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05111	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0000166//nucleotide binding;GO:0001540//amyloid-beta binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	"GO:0000902//cell morphogenesis;GO:0001525//angiogenesis;GO:0001655//urogenital system development;GO:0001933//negative regulation of protein phosphorylation;GO:0002639//positive regulation of immunoglobulin production;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0007162//negative regulation of cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007611//learning or memory;GO:0007612//learning;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021631//optic nerve morphogenesis;GO:0021934//hindbrain tangential cell migration;GO:0021952//central nervous system projection neuron axonogenesis;GO:0022038//corpus callosum development;GO:0030193//regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0031290//retinal ganglion cell axon guidance;GO:0031915//positive regulation of synaptic plasticity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033674//positive regulation of kinase activity;GO:0042113//B cell activation;GO:0042472//inner ear morphogenesis;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048013//ephrin receptor signaling pathway;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0048593//camera-type eye morphogenesis;GO:0050770//regulation of axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0050878//regulation of body fluid levels;GO:0051489//regulation of filopodium assembly;GO:0051963//regulation of synapse assembly;GO:0051965//positive regulation of synapse assembly;GO:0060021//roof of mouth development;GO:0060996//dendritic spine development;GO:0060997//dendritic spine morphogenesis;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071679//commissural neuron axon guidance;GO:0097104//postsynaptic membrane assembly;GO:0099557//trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission;GO:0106028//neuron projection retraction;GO:0110077//vesicle-mediated intercellular transport;GO:0120192//tight junction assembly;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904646//cellular response to amyloid-beta;GO:1904782//negative regulation of NMDA glutamate receptor activity;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:2000316//regulation of T-helper 17 type immune response;GO:2000822//regulation of behavioral fear response"	--
ENSG00000133226	19.296	19.728	16.453	14.813	14.768	18.078	1349	1405	861	771	898	939	SRRM1	serine and arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:16638]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K13171;K13171	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000133243	43.431	42.875	48.395	51.021	53.313	50.399	2365	2350	1939	2043	2429	1988	BTBD2	BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:15504]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0022008//neurogenesis	--
ENSG00000133246	0.022	0	0	0.059	0.052	0.06	1	0	0	2	2	2	PRAM1	PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091]	-	-	-	-	GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding	GO:0007229//integrin-mediated signaling pathway;GO:0043313//regulation of neutrophil degranulation;GO:0050852//T cell receptor signaling pathway;GO:0072659//protein localization to plasma membrane	--
ENSG00000133247	1.906	2.248	2.144	2.46	2.589	2.26	87	100	68	86	102	77	KMT5C	lysine methyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:28405]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11429;K11429	"GO:0000779//condensed chromosome, centromeric region;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042393//histone binding;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0046872//metal ion binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0016571//histone methylation;GO:0032259//methylation;GO:0034770//histone H4-K20 methylation;GO:0034772//histone H4-K20 dimethylation;GO:0034773//histone H4-K20 trimethylation;GO:0045830//positive regulation of isotype switching;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000133250	5.228	5.331	6.822	5.779	8.016	6.755	145	168	145	128	201	135	ZNF414	zinc finger protein 414 [Source:HGNC Symbol;Acc:HGNC:20630]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	Others
ENSG00000133256	15.058	15.373	9.376	14.693	9.333	10.611	627	568	369	343	363	251	PDE6B	phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04744//Phototransduction	K13756;K13756;K13756	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane;GO:0097381//photoreceptor disc membrane	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	"GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007603//phototransduction, visible light;GO:0009583//detection of light stimulus;GO:0043153//entrainment of circadian clock by photoperiod;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:1990009//retinal cell apoptotic process"	--
ENSG00000133265	15.789	13.791	17.848	17.729	14.316	17.157	419	397	345	375	352	329	HSPBP1	HSPA (Hsp70) binding protein 1 [Source:HGNC Symbol;Acc:HGNC:24989]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09562	-	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0006457//protein folding;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043086//negative regulation of catalytic activity	--
ENSG00000133275	32.896	34.438	34.475	40.966	38.692	30.818	1683	1765	1415	1391	1552	1237	CSNK1G2	casein kinase 1 gamma 2 [Source:HGNC Symbol;Acc:HGNC:2455]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K08958	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000133302	1.226	0.988	0.596	0.583	0.736	0.688	142	115	51	50	72	58	SLF1	SMC5-SMC6 complex localization factor 1 [Source:HGNC Symbol;Acc:HGNC:25408]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030915//Smc5-Smc6 complex;GO:0035861//site of double-strand break;GO:0042405//nuclear inclusion body;GO:0043229//intracellular organelle"	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032204//regulation of telomere maintenance;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:1990166//protein localization to site of double-strand break;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000133313	68.79	73.685	75.351	70.826	72.263	68.28	3072	3320	2423	2396	2815	2238	CNDP2	carnosine dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:24437]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism	K08660;K08660;K08660;K08660	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity;GO:0103046//alanylglutamate dipeptidase activity	GO:0006508//proteolysis	--
ENSG00000133315	10.394	10.493	13.53	15.021	14.936	15.656	271	275	260	289	329	297	MACROD1	mono-ADP ribosylhydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29598]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019213//deacetylase activity;GO:0140293//ADP-ribosylglutamate hydrolase activity"	GO:0006974//cellular response to DNA damage stimulus;GO:0042278//purine nucleoside metabolic process;GO:0051725//protein de-ADP-ribosylation;GO:0140291//peptidyl-glutamate ADP-deribosylation	--
ENSG00000133316	10.436	10.585	10.663	10.24	10.346	10.204	294	293	210	207	232	197	WDR74	WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529]	-	-	-	-	"GO:0000176//nuclear exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor"	GO:0005515//protein binding	GO:0001825//blastocyst formation;GO:0006364//rRNA processing;GO:0016070//RNA metabolic process;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000133317	2.328	3.153	1.671	1.565	1.413	1.736	86	108	41	36	40	45	LGALS12	galectin 12 [Source:HGNC Symbol;Acc:HGNC:15788]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005178//integrin binding;GO:0030246//carbohydrate binding;GO:0030395//lactose binding	GO:0006915//apoptotic process;GO:0045598//regulation of fat cell differentiation;GO:0050994//regulation of lipid catabolic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:1904977//lymphatic endothelial cell migration	--
ENSG00000133318	89.14	88.014	84.893	92.221	89.207	87.453	4653	4648	3278	3562	3961	3325	RTN3	reticulon 3 [Source:HGNC Symbol;Acc:HGNC:10469]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K20723	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0016192//vesicle-mediated transport;GO:0071786//endoplasmic reticulum tubular network organization;GO:0071787//endoplasmic reticulum tubular network formation;GO:1902430//negative regulation of amyloid-beta formation	--
ENSG00000133321	12.975	14.87	17.826	17.602	11.067	13.025	204	235	207	205	147	149	PLAAT4	phospholipase A and acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:9869]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008970//phospholipase A1 activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0016042//lipid catabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0045618//positive regulation of keratinocyte differentiation;GO:0070292//N-acylphosphatidylethanolamine metabolic process;GO:0150074//positive regulation of protein-glutamine gamma-glutamyltransferase activity	--
ENSG00000133328	0	0	0	0.088	0	0	0	0	0	1	0	0	PLAAT2	phospholipase A and acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:17824]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko04923//Regulation of lipolysis in adipocytes;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16817;K16817;K16817;K16817;K16817;K16817;K16817;K16817	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008970//phospholipase A1 activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0070292//N-acylphosphatidylethanolamine metabolic process	--
ENSG00000133392	1.104	1.147	0.942	1.267	1.347	1.504	157	162	99	133.24	161.76	156	MYH11	myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Circulatory system	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04530//Tight junction;ko04270//Vascular smooth muscle contraction	K10352;K10352;K10352;K10352	GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0032982//myosin filament;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008307//structural constituent of muscle;GO:0051015//actin filament binding	GO:0006939//smooth muscle contraction;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0048251//elastic fiber assembly;GO:0055013//cardiac muscle cell development	--
ENSG00000133393	10.406	11.193	9.471	8.516	8.688	10.772	453	404	279	279	301	286	CEP20	centrosomal protein 20 [Source:HGNC Symbol;Acc:HGNC:26435]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0030030//cell projection organization;GO:0034453//microtubule anchoring;GO:0060271//cilium assembly	--
ENSG00000133398	7.575	7.842	6.937	8.217	6.893	9.87	173	180	117	139	133	164	MED10	mediator complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:28760]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000133401	17.331	15.85	15.295	15.578	17.379	18.509	4308	3781	2808	2755	3458	3167	PDZD2	PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18486]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0007155//cell adhesion	--
ENSG00000133422	9.115	9.596	9.976	8.09	8.064	7.836	943	966	650	630	736	637	MORC2	MORC family CW-type zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:23573]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0006338//chromatin remodeling;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly"	--
ENSG00000133424	9.64	11.535	10.169	8.09	9.599	10.44	777	942	506	487	665	497	LARGE1	LARGE xylosyl- and glucuronyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:6511]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K09668;K09668	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0030145//manganese ion binding;GO:0035252//UDP-xylosyltransferase activity;GO:0042285//xylosyltransferase activity;GO:0046872//metal ion binding	GO:0006044//N-acetylglucosamine metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0008152//metabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0035269//protein O-linked mannosylation;GO:0043403//skeletal muscle tissue regeneration;GO:0046716//muscle cell cellular homeostasis;GO:0060538//skeletal muscle organ development	--
ENSG00000133433	20.501	19.824	17.812	16.362	15.469	18.256	448.19	448.65	298.35	268.9	295.84	300.1	GSTT2B	glutathione S-transferase theta 2B [Source:HGNC Symbol;Acc:HGNC:33437]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006749//glutathione metabolic process	--
ENSG00000133454	0.019	0.017	0.008	0.083	0.021	0.042	3	3	1	4	3	2	MYO18B	myosin XVIIIB [Source:HGNC Symbol;Acc:HGNC:18150]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016459//myosin complex;GO:0016461//unconventional myosin complex;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0055013//cardiac muscle cell development	--
ENSG00000133460	6.98	3.377	5.869	5.32	5.477	6.284	193	146.01	150.22	153	156.22	146	SLC2A11	solute carrier family 2 member 11 [Source:HGNC Symbol;Acc:HGNC:14239]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005355//glucose transmembrane transporter activity;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0051119//sugar transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0015749//monosaccharide transmembrane transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000133466	10.97	11.091	12.15	15.573	15.245	12.947	603	627	493	635	698	527	C1QTNF6	C1q and TNF related 6 [Source:HGNC Symbol;Acc:HGNC:14343]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000133475	0	0	0	0	0.048	0	0	0	0	0	2	0	GGT2	gamma-glutamyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4251]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0036374//glutathione hydrolase activity	GO:0002682//regulation of immune system process;GO:0006508//proteolysis;GO:0006751//glutathione catabolic process;GO:0031179//peptide modification;GO:0050727//regulation of inflammatory response;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000133477	0.028	0.075	0	0.037	0.007	0	3	3	0	2	2	0	FAM83F	family with sequence similarity 83 member F [Source:HGNC Symbol;Acc:HGNC:25148]	-	-	-	-	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007165//signal transduction	--
ENSG00000133488	0	0	0	0	0	0	0	0	0	0	0	0	SEC14L4	SEC14 like lipid binding 4 [Source:HGNC Symbol;Acc:HGNC:20627]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008289//lipid binding	-	--
ENSG00000133561	0	0	0	0	0	0	0	0	0	0	0	0	GIMAP6	"GTPase, IMAP family member 6 [Source:HGNC Symbol;Acc:HGNC:21918]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005525//GTP binding	-	--
ENSG00000133574	0	0	0	0	0.117	0	0	0	0	0	4	0	GIMAP4	"GTPase, IMAP family member 4 [Source:HGNC Symbol;Acc:HGNC:21872]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005525//GTP binding	-	--
ENSG00000133597	6.069	6.269	6.086	7.788	7.874	7.234	324	320	240	308	329	281	ADCK2	aarF domain containing kinase 2 [Source:HGNC Symbol;Acc:HGNC:19039]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000133606	33.222	34.426	37.338	35.748	34.442	34.803	1998	2075	1565	1602	1740	1501	MKRN1	makorin ring finger protein 1 [Source:HGNC Symbol;Acc:HGNC:7112]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination	--
ENSG00000133612	53.39	51.725	55.5	64.426	59.682	67.086	2569	2443	1985	2169	2410	2236	AGAP3	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:16923]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding	GO:0034614//cellular response to reactive oxygen species;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000133619	4.684	4.058	4.557	5.026	4.608	3.612	355	311	249	253	283	184	KRBA1	KRAB-A domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22228]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	"GO:0006355//regulation of transcription, DNA-templated;GO:0008150//biological_process"	--
ENSG00000133627	5.848	5.984	5.941	7.648	7.519	5.601	225.88	253.91	168	218.94	250.91	172	ACTR3B	actin related protein 3B [Source:HGNC Symbol;Acc:HGNC:17256]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584;K18584	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0008150//biological_process	--
ENSG00000133636	0.117	0.077	0	0	0	0.053	3	2	0	0	0	1	NTS	neurotensin [Source:HGNC Symbol;Acc:HGNC:8038]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05235	GO:0005576//extracellular region;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus	GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity;GO:0071855//neuropeptide receptor binding	GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000133639	17.143	15.833	15.47	13.85	13.647	16.705	1646	1528	1097	985	1107	1167	BTG1	BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019900//kinase binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006479//protein methylation;GO:0006979//response to oxidative stress;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0016477//cell migration;GO:0030308//negative regulation of cell growth;GO:0043434//response to peptide hormone;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045930//negative regulation of mitotic cell cycle;GO:2000271//positive regulation of fibroblast apoptotic process"	--
ENSG00000133640	0.514	0.805	0.372	0.06	0.148	0.233	26	24	14	5	14	6	LRRIQ1	leucine rich repeats and IQ motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25708]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000133641	2.239	1.389	1.546	2.105	1.919	1.4	127.75	77.76	51.89	68.93	61	48	C12orf29	chromosome 12 open reading frame 29 [Source:HGNC Symbol;Acc:HGNC:25322]	-	-	-	-	-	-	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000133657	26.44	20.776	21.462	20.138	20.642	24.288	4110	3256	2472	2308	2723	2756	ATP13A3	ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0015594//ABC-type putrescine transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis;GO:0015847//putrescine transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000133661	0.758	0.701	0.305	0.659	0.712	0.614	18	15	6	13	16	8	SFTPD	surfactant protein D [Source:HGNC Symbol;Acc:HGNC:10803]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K10068	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005771//multivesicular body;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0030139//endocytic vesicle;GO:0045334//clathrin-coated endocytic vesicle	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding	GO:0001817//regulation of cytokine production;GO:0002376//immune system process;GO:0006898//receptor-mediated endocytosis;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0032703//negative regulation of interleukin-2 production;GO:0042130//negative regulation of T cell proliferation;GO:0042742//defense response to bacterium;GO:0043129//surfactant homeostasis;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0048246//macrophage chemotaxis;GO:0048286//lung alveolus development;GO:0050766//positive regulation of phagocytosis;GO:0052403//negative regulation by host of symbiont catalytic activity;GO:0072593//reactive oxygen species metabolic process;GO:1905226//regulation of adhesion of symbiont to host epithelial cell	--
ENSG00000133665	0.348	0.174	0.056	0	0.049	0	4	2	1	0	1	0	DYDC2	DPY30 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23468]	-	-	-	-	GO:0005634//nucleus;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex	GO:0005515//protein binding	GO:0051568//histone H3-K4 methylation	--
ENSG00000133678	16.299	17.273	15.142	18.29	17.522	15.531	661	698	448	513	619	470	TMEM254	transmembrane protein 254 [Source:HGNC Symbol;Acc:HGNC:25804]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000133687	14.944	13.7	15.289	11.789	11.354	13.124	2186	2015	1654	1369	1392	1469	TMTC1	transmembrane O-mannosyltransferase targeting cadherins 1 [Source:HGNC Symbol;Acc:HGNC:24099]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006396//RNA processing;GO:0006486//protein glycosylation;GO:0035269//protein O-linked mannosylation	--
ENSG00000133703	5.569	4.798	4.659	4.797	4.446	5.006	609	531	376	390	414.03	395	KRAS	"KRAS proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:6407]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Development and regeneration;Cancer: overview;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Nervous system;Nervous system;Endocrine system;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Aging;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Transport and catabolism;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Aging;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Excretory system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko04960//Aldosterone-regulated sodium reabsorption;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827;K07827	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008542//visual learning;GO:0010628//positive regulation of gene expression;GO:0021897//forebrain astrocyte development;GO:0030036//actin cytoskeleton organization;GO:0031647//regulation of protein stability;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035022//positive regulation of Rac protein signal transduction;GO:0038002//endocrine signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048873//homeostasis of number of cells within a tissue;GO:0051146//striated muscle cell differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis"	--
ENSG00000133704	15.802	12.946	13.95	11.028	14.23	11.594	1358	1116	889	738	1022	818	IPO8	importin 8 [Source:HGNC Symbol;Acc:HGNC:9853]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K18755	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0015031//protein transport	--
ENSG00000133706	30.835	30.382	27.676	24.414	26.938	26.652	2489	2371	1623	1551	1770	1638	LARS1	leucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6512]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01869	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016604//nuclear body;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004819//glutamine-tRNA ligase activity;GO:0004823//leucine-tRNA ligase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006425//glutaminyl-tRNA aminoacylation;GO:0006429//leucyl-tRNA aminoacylation;GO:0008361//regulation of cell size;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0043547//positive regulation of GTPase activity;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity;GO:1904263//positive regulation of TORC1 signaling;GO:1990253//cellular response to leucine starvation	--
ENSG00000133710	0.396	0.201	0.442	0.249	0.517	0.182	30	14	10	14	26	8	SPINK5	serine peptidase inhibitor Kazal type 5 [Source:HGNC Symbol;Acc:HGNC:15464]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0097209//epidermal lamellar body	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0002787//negative regulation of antibacterial peptide production;GO:0007417//central nervous system development;GO:0009913//epidermal cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030198//extracellular matrix organization;GO:0030855//epithelial cell differentiation;GO:0035315//hair cell differentiation;GO:0045580//regulation of T cell differentiation;GO:0045861//negative regulation of proteolysis;GO:0050777//negative regulation of immune response;GO:0051884//regulation of timing of anagen;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:1902572//negative regulation of serine-type peptidase activity	--
ENSG00000133731	11.687	8.292	10.497	8.886	7.561	9.72	493	410	345	295	327	374	IMPA1	inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01092;K01092;K01092	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0031403//lithium ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0052834//inositol monophosphate phosphatase activity	GO:0006020//inositol metabolic process;GO:0006021//inositol biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation	--
ENSG00000133739	1.308	0.884	0.966	0.573	0.729	1.047	85	60	42	32	44	43	LRRCC1	leucine rich repeat and coiled-coil centrosomal protein 1 [Source:HGNC Symbol;Acc:HGNC:29373]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000133740	7.055	6.342	7.119	6.727	7.374	9.742	280.05	262.18	202.31	193.37	224.07	262.69	E2F5	E2F transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3119]	Cellular Processes;Cellular Processes;Environmental Information Processing	Cell growth and death;Cell growth and death;Signal transduction	ko04218//Cellular senescence;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway	K04682;K04682;K04682	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0030030//cell projection organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle"	E2F
ENSG00000133742	0	0	0	0	0.031	0	0	0	0	0	1	0	CA1	carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:1368]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004064//arylesterase activity;GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process	--
ENSG00000133773	4.745	4.299	3.489	2.874	3.06	4.643	156	124	72	70	85	91	CCDC59	coiled-coil domain containing 59 [Source:HGNC Symbol;Acc:HGNC:25005]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000133789	10.373	9.625	8.657	8.058	8.48	7.397	998	886	608	556	650	516	SWAP70	switching B cell complex subunit SWAP70 [Source:HGNC Symbol;Acc:HGNC:17070]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0045296//cadherin binding	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008064//regulation of actin polymerization or depolymerization;GO:0016444//somatic cell DNA recombination;GO:0030835//negative regulation of actin filament depolymerization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0032880//regulation of protein localization;GO:0033633//negative regulation of cell-cell adhesion mediated by integrin;GO:0045190//isotype switching;GO:0050790//regulation of catalytic activity;GO:0051017//actin filament bundle assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060754//positive regulation of mast cell chemotaxis;GO:1902309//negative regulation of peptidyl-serine dephosphorylation	--
ENSG00000133794	4.627	3.959	3.712	4.877	4.203	5.102	252	224	154	151	203	186	ARNTL	aryl hydrocarbon receptor nuclear translocator like [Source:HGNC Symbol;Acc:HGNC:701]	Organismal Systems;Organismal Systems	Nervous system;Environmental adaptation	ko04728//Dopaminergic synapse;ko04710//Circadian rhythm	K02296;K02296	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0033391//chromatoid body;GO:0034751//aryl hydrocarbon receptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:1990513//CLOCK-BMAL transcription complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0032007//negative regulation of TOR signaling;GO:0032922//circadian regulation of gene expression;GO:0042634//regulation of hair cycle;GO:0042753//positive regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis;GO:0050796//regulation of insulin secretion;GO:0051726//regulation of cell cycle;GO:0051775//response to redox state;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090403//oxidative stress-induced premature senescence;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901985//positive regulation of protein acetylation;GO:2000074//regulation of type B pancreatic cell development;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:2000772//regulation of cellular senescence;GO:2001016//positive regulation of skeletal muscle cell differentiation"	bHLH
ENSG00000133800	0	0.03	0	0	0.035	0	0	2	0	0	2	0	LYVE1	lymphatic vessel endothelial hyaluronan receptor 1 [Source:HGNC Symbol;Acc:HGNC:14687]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0038023//signaling receptor activity	GO:0002693//positive regulation of cellular extravasation;GO:0006027//glycosaminoglycan catabolic process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0009611//response to wounding;GO:0009653//anatomical structure morphogenesis	--
ENSG00000133805	1.236	1.038	1.442	1.339	1.709	1.626	90	76	74	76	94	84	AMPD3	adenosine monophosphate deaminase 3 [Source:HGNC Symbol;Acc:HGNC:470]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01490;K01490	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003876//AMP deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019239//deaminase activity;GO:0046872//metal ion binding	GO:0006188//IMP biosynthetic process;GO:0006196//AMP catabolic process;GO:0009117//nucleotide metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0032264//IMP salvage;GO:0046033//AMP metabolic process;GO:0072521//purine-containing compound metabolic process	--
ENSG00000133812	10.802	9.549	10.626	7.894	9.062	9.166	1553	1354	1061	854	1040	941	SBF2	SET binding factor 2 [Source:HGNC Symbol;Acc:HGNC:2135]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity;GO:0019902//phosphatase binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0006914//autophagy;GO:0042552//myelination;GO:0043087//regulation of GTPase activity	--
ENSG00000133816	9.125	9.576	4.411	3.885	8.897	4.513	533	583	174	180	337	209	MICAL2	"microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693]"	-	-	-	-	GO:0005634//nucleus	"GO:0003779//actin binding;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0043914//NADPH:sulfur oxidoreductase activity;GO:0046872//metal ion binding;GO:0071949//FAD binding"	GO:0001947//heart looping;GO:0007010//cytoskeleton organization;GO:0007507//heart development;GO:0010735//positive regulation of transcription via serum response element binding;GO:0019417//sulfur oxidation;GO:0030042//actin filament depolymerization	--
ENSG00000133818	17.622	15.978	15.524	13.908	16.097	18.222	731.95	637.99	448	400	498	484	RRAS2	RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cell growth and death;Transport and catabolism;Signal transduction;Immune system;Transport and catabolism	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04137//Mitophagy - animal	K07830;K07830;K07830;K07830;K07830;K07830;K07830;K07830;K07830;K07830;K07830	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0030335//positive regulation of cell migration;GO:1901214//regulation of neuron death	--
ENSG00000133835	49.177	47.203	50.182	42.777	45.853	51.859	2709	2612	2054	1743	2139	2080	HSD17B4	hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids;ko00120//Primary bile acid biosynthesis	K12405;K12405;K12405;K12405;K12405	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane	"GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0016491//oxidoreductase activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0033989//3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity;GO:0042803//protein homodimerization activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0106386//(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity"	GO:0000038//very long-chain fatty acid metabolic process;GO:0001649//osteoblast differentiation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0036111//very long-chain fatty-acyl-CoA metabolic process;GO:0036112//medium-chain fatty-acyl-CoA metabolic process;GO:0060009//Sertoli cell development	--
ENSG00000133858	2.846	1.861	1.799	1.633	2.338	1.887	416	273	195	167	281	201	ZFC3H1	zinc finger C3H1-type containing [Source:HGNC Symbol;Acc:HGNC:28328]	-	-	-	-	GO:0000178//exosome (RNase complex);GO:0005615//extracellular space;GO:0005634//nucleus	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006396//RNA processing	--
ENSG00000133863	0	0	0	0	0	0	0	0	0	0	0	0	TEX15	"testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	GO:0006281//DNA repair;GO:0006306//DNA methylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0051321//meiotic cell cycle	--
ENSG00000133872	425.122	415.291	369.878	353.992	370.252	322.965	17590	17310	11339	10838	12953	9765	SARAF	store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000133874	9.349	10.813	9.868	6.919	8.505	10.265	363	422	283	199	279	290	RNF122	ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010917//negative regulation of mitochondrial membrane potential;GO:0043065//positive regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination	--
ENSG00000133878	4.031	6.027	3.549	2.078	2.861	2.569	139	203	82	56	84	68	DUSP26	dual specificity phosphatase 26 [Source:HGNC Symbol;Acc:HGNC:28161]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome	GO:0002039//p53 binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0045785//positive regulation of cell adhesion;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000133884	19.777	19.52	18.816	19.317	20.799	18.881	1135	1153	843	863	1027	826	DPF2	double PHD fingers 2 [Source:HGNC Symbol;Acc:HGNC:9964]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016514//SWI/SNF complex;GO:0043231//intracellular membrane-bounded organelle;GO:0071565//nBAF complex	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0062072//H3K9me3 modified histone binding;GO:0070577//lysine-acetylated histone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:0097190//apoptotic signaling pathway;GO:1902459//positive regulation of stem cell population maintenance;GO:1905454//negative regulation of myeloid progenitor cell differentiation;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000133895	14.714	17.529	14.777	18.03	16.041	15.57	791	987	634	774	784	659	MEN1	menin 1 [Source:HGNC Symbol;Acc:HGNC:7010]	Human Diseases;Human Diseases	Cancer: overview;Endocrine and metabolic disease	ko05202//Transcriptional misregulation in cancer;ko04934//Cushing syndrome	K14970;K14970	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0017053//transcription repressor complex;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex;GO:0071339//MLL1 complex"	GO:0000400//four-way junction DNA binding;GO:0000403//Y-form DNA binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0047485//protein N-terminus binding;GO:0051219//phosphoprotein binding;GO:0070412//R-SMAD binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0000278//mitotic cell cycle;GO:0001933//negative regulation of protein phosphorylation;GO:0002076//osteoblast development;GO:0003309//type B pancreatic cell differentiation;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0009411//response to UV;GO:0010332//response to gamma radiation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032092//positive regulation of protein binding;GO:0032925//regulation of activin receptor signaling pathway;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045668//negative regulation of osteoblast differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0046697//decidualization;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051568//histone H3-K4 methylation;GO:0051974//negative regulation of telomerase activity;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0071333//cellular response to glucose stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0071559//response to transforming growth factor beta;GO:1902807//negative regulation of cell cycle G1/S phase transition"	--
ENSG00000133935	21.861	20.902	24.62	25.501	27.622	26.676	1052	1011	875	909	1123	934	ERG28	ergosterol biosynthesis 28 homolog [Source:HGNC Symbol;Acc:HGNC:1187]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008150//biological_process;GO:0008202//steroid metabolic process;GO:0016126//sterol biosynthetic process	--
ENSG00000133937	0	0	0.057	0	0.05	0	0	0	1	0	1	0	GSC	goosecoid homeobox [Source:HGNC Symbol;Acc:HGNC:4612]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007369//gastrulation;GO:0009653//anatomical structure morphogenesis;GO:0014036//neural crest cell fate specification;GO:0021904//dorsal/ventral neural tube patterning;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030900//forebrain development;GO:0042474//middle ear morphogenesis;GO:0043583//ear development;GO:0048644//muscle organ morphogenesis;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000133943	20.074	21.174	24.69	28.985	27.395	24.979	870.76	971	790.74	916	1009	734	DGLUCY	D-glutamate cyclase [Source:HGNC Symbol;Acc:HGNC:20498]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00470//D-Amino acid metabolism	K22210;K22210	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0047820//D-glutamate cyclase activity	GO:0006536//glutamate metabolic process;GO:0008150//biological_process	--
ENSG00000133958	0.026	0.038	0	0.044	0.014	0.027	4	7	0	6	2	3	UNC79	"unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000133961	17.537	16.601	16.173	13.484	16.674	15.704	1056	989	736	614	781	744	NUMB	NUMB endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06057	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding	GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0007409//axonogenesis;GO:0021670//lateral ventricle development;GO:0021849//neuroblast division in subventricular zone;GO:0030335//positive regulation of cell migration;GO:0030900//forebrain development;GO:0034332//adherens junction organization;GO:0050769//positive regulation of neurogenesis;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000133962	0.022	0.026	0	0	0	0	1	2	0	0	0	0	CATSPERB	cation channel sperm associated auxiliary subunit beta [Source:HGNC Symbol;Acc:HGNC:20500]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036128//CatSper complex;GO:0097228//sperm principal piece	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000133980	0	0	0	0	0	0	0	0	0	0	0	0	VRTN	vertebrae development associated [Source:HGNC Symbol;Acc:HGNC:20223]	-	-	-	-	GO:0000785//chromatin	GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000133983	15.455	15.538	16.74	17.096	14.285	14.213	535.03	540.65	428	438.4	417.8	358	COX16	cytochrome c oxidase assembly factor COX16 [Source:HGNC Symbol;Acc:HGNC:20213]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18182	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000133985	15.9	14.727	16.787	15.499	14.384	17.638	1680	1564	1310	1213	1284	1356	TTC9	tetratricopeptide repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20267]	-	-	-	-	-	GO:0005515//protein binding	GO:0060348//bone development	--
ENSG00000133997	12.409	12.327	11.758	10.483	8.856	9.666	410	438	307	273	276	242	MED6	mediator complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:19970]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000134001	11.872	10.432	15.017	11.895	9.994	12.209	875	737	648	480	532	574	EIF2S1	eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	"Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Infectious disease: viral;Folding, sorting and degradation;Endocrine and metabolic disease;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cell growth and death"	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05020//Prion disease;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko05164//Influenza A;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko05162//Measles;ko04210//Apoptosis	K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237;K03237	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0033290//eukaryotic 48S preinitiation complex;GO:0043614//multi-eIF complex;GO:0044207//translation initiation ternary complex;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0097451//glial limiting end-foot	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0007568//aging;GO:0032057//negative regulation of translational initiation in response to stress;GO:0034063//stress granule assembly;GO:0034198//cellular response to amino acid starvation;GO:0034599//cellular response to oxidative stress;GO:0034605//cellular response to heat;GO:0034644//cellular response to UV;GO:0034976//response to endoplasmic reticulum stress;GO:0036499//PERK-mediated unfolded protein response;GO:0043558//regulation of translational initiation in response to stress;GO:0046777//protein autophosphorylation;GO:1901216//positive regulation of neuron death;GO:1905098//negative regulation of guanyl-nucleotide exchange factor activity;GO:1990737//response to manganese-induced endoplasmic reticulum stress;GO:2000676//positive regulation of type B pancreatic cell apoptotic process	--
ENSG00000134007	0	0.017	0.07	0	0	0.024	0	1	3	0	0	1	ADAM20	ADAM metallopeptidase domain 20 [Source:HGNC Symbol;Acc:HGNC:199]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990913//sperm head plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007338//single fertilization;GO:0008584//male gonad development	--
ENSG00000134013	22.298	23.531	16.517	10.494	12.102	10.251	1480	1562	830	435	606	476	LOXL2	lysyl oxidase like 2 [Source:HGNC Symbol;Acc:HGNC:6666]	-	-	-	-	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix	"GO:0004720//protein-lysine 6-oxidase activity;GO:0005044//scavenger receptor activity;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0001837//epithelial to mesenchymal transition;GO:0001935//endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0006325//chromatin organization;GO:0006464//cellular protein modification process;GO:0006897//endocytosis;GO:0007155//cell adhesion;GO:0007568//aging;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0018057//peptidyl-lysine oxidation;GO:0022900//electron transport chain;GO:0030199//collagen fibril organization;GO:0032332//positive regulation of chondrocyte differentiation;GO:0043542//endothelial cell migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046688//response to copper ion;GO:0070828//heterochromatin organization;GO:1902455//negative regulation of stem cell population maintenance"	--
ENSG00000134014	14.639	19.516	16.177	12.994	16.116	17.867	708	692	493	444	573	534	ELP3	elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0033588//elongator holoenzyme complex	"GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0008607//phosphorylase kinase regulator activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0106261//tRNA uridine(34) acetyltransferase activity"	GO:0001764//neuron migration;GO:0002098//tRNA wobble uridine modification;GO:0002926//tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006417//regulation of translation;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0008033//tRNA processing;GO:0030335//positive regulation of cell migration;GO:0050790//regulation of catalytic activity	--
ENSG00000134020	2.194	2.461	1.552	1.152	1.212	1.765	41	34.65	19.16	14.03	17.02	24	PEBP4	phosphatidylethanolamine binding protein 4 [Source:HGNC Symbol;Acc:HGNC:28319]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000134028	0	0	0	0	0	0	0	0	0	0	0	0	ADAMDEC1	ADAM like decysin 1 [Source:HGNC Symbol;Acc:HGNC:16299]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006955//immune response;GO:0007162//negative regulation of cell adhesion	--
ENSG00000134030	12.578	11.472	11.762	12.74	12.639	13.71	1331	1243	941	1010	1137	1073	CTIF	cap binding complex dependent translation initiation factor [Source:HGNC Symbol;Acc:HGNC:23925]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008494//translation activator activity	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation"	--
ENSG00000134042	0.864	0.443	0.911	1.17	0.767	1.163	66	48	67	55	57	69	MRO	maestro [Source:HGNC Symbol;Acc:HGNC:24121]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	-	-	--
ENSG00000134046	7.267	6.853	7.087	6.44	6.537	6.326	702	638	469	430	512	479	MBD2	methyl-CpG binding domain protein 2 [Source:HGNC Symbol;Acc:HGNC:6917]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016581//NuRD complex;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003696//satellite DNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0019904//protein domain specific binding;GO:0031492//nucleosomal DNA binding;GO:0035197//siRNA binding;GO:0070742//C2H2 zinc finger domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006346//DNA methylation-dependent heterochromatin assembly;GO:0007507//heart development;GO:0007568//aging;GO:0009612//response to mechanical stimulus;GO:0014070//response to organic cyclic compound;GO:0016575//histone deacetylation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0034622//cellular protein-containing complex assembly;GO:0035563//positive regulation of chromatin binding;GO:0042127//regulation of cell population proliferation;GO:0042711//maternal behavior;GO:0044030//regulation of DNA methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048568//embryonic organ development;GO:0071407//cellular response to organic cyclic compound"	MBD
ENSG00000134049	9.75	8.681	10.142	8.686	8.469	9.762	744	658	556	491	546	542	IER3IP1	immediate early response 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18550]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding	GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007420//brain development;GO:0015031//protein transport;GO:0035265//organ growth;GO:0050714//positive regulation of protein secretion;GO:2000269//regulation of fibroblast apoptotic process	--
ENSG00000134056	5.214	4.993	5.403	4.911	4.296	6.894	142	136	108	99	99	135	MRPS36	mitochondrial ribosomal protein S36 [Source:HGNC Symbol;Acc:HGNC:16631]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005840//ribosome;GO:0009353//mitochondrial oxoglutarate dehydrogenase complex	-	GO:0006099//tricarboxylic acid cycle;GO:0006103//2-oxoglutarate metabolic process	--
ENSG00000134057	8.698	7.601	8.654	6.455	5.791	6.726	243	243	199	161	155	147	CCNB1	cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]	Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes	Infectious disease: viral;Cell growth and death;Cell growth and death;Signal transduction;Cell growth and death;Endocrine system;Cell growth and death	ko05170//Human immunodeficiency virus 1 infection;ko04218//Cellular senescence;ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko04115//p53 signaling pathway	K05868;K05868;K05868;K05868;K05868;K05868;K05868	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0097125//cyclin B1-CDK1 complex	GO:0005113//patched binding;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001701//in utero embryonic development;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007080//mitotic metaphase plate congression;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045787//positive regulation of cell cycle;GO:0045931//positive regulation of mitotic cell cycle;GO:0048146//positive regulation of fibroblast proliferation;GO:0051301//cell division;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:1905448//positive regulation of mitochondrial ATP synthesis coupled electron transport	--
ENSG00000134058	11.265	10.718	10.209	9.539	10.176	9.189	296	289	194	184	234	194	CDK7	cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778]	Cellular Processes;Genetic Information Processing;Genetic Information Processing	Cell growth and death;Transcription;Replication and repair	ko04110//Cell cycle;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K02202;K02202;K02202	GO:0000439//transcription factor TFIIH core complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005675//transcription factor TFIIH holo complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0048471//perinuclear region of cytoplasm;GO:0070516//CAK-ERCC2 complex;GO:0070985//transcription factor TFIIK complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity"	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006281//DNA repair;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0042795//snRNA transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000134061	0	0	0	0	0.011	0	0	0	0	0	1	0	CD180	CD180 molecule [Source:HGNC Symbol;Acc:HGNC:6726]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0072686//mitotic spindle	GO:0005515//protein binding	GO:0002322//B cell proliferation involved in immune response;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000134070	2.192	1.692	2.131	2.144	2.362	2.028	156	121	112	113	142	105	IRAK2	interleukin 1 receptor associated kinase 2 [Source:HGNC Symbol;Acc:HGNC:6113]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Nervous system	ko05152//Tuberculosis;ko04722//Neurotrophin signaling pathway	K04731;K04731	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0019221//cytokine-mediated signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0035556//intracellular signal transduction;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1	--
ENSG00000134072	7.187	9.368	9.562	8.264	7.994	7.036	201	254	194	177	181	141	CAMK1	calcium/calmodulin dependent protein kinase I [Source:HGNC Symbol;Acc:HGNC:1459]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Endocrine system;Endocrine system;Cancer: specific types	ko04020//Calcium signaling pathway;ko04921//Oxytocin signaling pathway;ko04925//Aldosterone synthesis and secretion;ko05214//Glioma	K08794;K08794;K08794;K08794	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0032091//negative regulation of protein binding;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043393//regulation of protein binding;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046827//positive regulation of protein export from nucleus;GO:0050807//regulation of synapse organization;GO:0051147//regulation of muscle cell differentiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0051835//positive regulation of synapse structural plasticity;GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0060999//positive regulation of dendritic spine development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1901985//positive regulation of protein acetylation	--
ENSG00000134077	20.568	17.465	20.428	18.465	16.298	16.929	948	850	605	554	624	622	THUMPD3	THUMP domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24493]	-	-	-	-	GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016423//tRNA (guanine) methyltransferase activity;GO:0016740//transferase activity	GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000134086	10.842	11.863	10.806	10.221	11.776	10.59	743	811	568	536	693	559	VHL	von Hippel-Lindau tumor suppressor [Source:HGNC Symbol;Acc:HGNC:12687]	Human Diseases;Genetic Information Processing;Environmental Information Processing;Human Diseases	"Cancer: overview;Folding, sorting and degradation;Signal transduction;Cancer: specific types"	ko05200//Pathways in cancer;ko04120//Ubiquitin mediated proteolysis;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K03871;K03871;K03871;K03871	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane	GO:0003711//transcription elongation regulator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0140297//DNA-binding transcription factor binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	"GO:0000902//cell morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0016567//protein ubiquitination;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0050821//protein stabilization;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia"	--
ENSG00000134107	96.622	93.221	81.12	78.694	91.155	75.594	6317	6126	3917	3811	5035	3596	BHLHE40	basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K03729	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0043425//bHLH transcription factor binding;GO:0043426//MRF binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009952//anterior/posterior pattern specification;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000134108	33.305	32.844	27.927	27.292	29.78	29.297	1936	1951	1249	1200	1519	1280	ARL8B	ADP ribosylation factor like GTPase 8B [Source:HGNC Symbol;Acc:HGNC:25564]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K07955	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0051233//spindle midzone;GO:0070062//extracellular exosome;GO:0101004//cytolytic granule membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding	GO:0001778//plasma membrane repair;GO:0002505//antigen processing and presentation of polysaccharide antigen via MHC class II;GO:0002747//antigen processing and presentation following phagocytosis;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0032418//lysosome localization;GO:0042267//natural killer cell mediated cytotoxicity;GO:0046754//viral exocytosis;GO:0051301//cell division;GO:0061909//autophagosome-lysosome fusion;GO:0090117//endosome to lysosome transport of low-density lipoprotein particle;GO:0090385//phagosome-lysosome fusion;GO:1902774//late endosome to lysosome transport;GO:1990927//calcium ion regulated lysosome exocytosis	--
ENSG00000134109	1.948	2.268	1.698	1.895	1.932	2.385	247	289	159	178	207	220	EDEM1	ER degradation enhancing alpha-mannosidase like protein 1 [Source:HGNC Symbol;Acc:HGNC:18967]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10084	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016235//aggresome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0051787//misfolded protein binding"	"GO:0005975//carbohydrate metabolic process;GO:0006986//response to unfolded protein;GO:0008152//metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036508//protein alpha-1,2-demannosylation;GO:0036510//trimming of terminal mannose on C branch;GO:0045047//protein targeting to ER;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway;GO:1904154//positive regulation of retrograde protein transport, ER to cytosol;GO:1904380//endoplasmic reticulum mannose trimming;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway"	--
ENSG00000134115	7.878	6.383	9.77	9.343	8.817	12.821	615	491	492	528	577	677	CNTN6	contactin 6 [Source:HGNC Symbol;Acc:HGNC:2176]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0099026//anchored component of presynaptic membrane	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007219//Notch signaling pathway;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0045747//positive regulation of Notch signaling pathway;GO:0070593//dendrite self-avoidance	--
ENSG00000134121	1.368	1.538	0.837	0.4	0.469	0.296	72	57	44	28	26	29	CHL1	cell adhesion molecule L1 like [Source:HGNC Symbol;Acc:HGNC:1939]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0002020//protease binding;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008344//adult locomotory behavior;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0035640//exploration behavior;GO:0043524//negative regulation of neuron apoptotic process;GO:0050890//cognition	--
ENSG00000134138	25.806	22.962	23.053	21.898	22.321	20.299	1174	1131	732	791	918	748	MEIS2	Meis homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7001]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0008542//visual learning;GO:0009612//response to mechanical stimulus;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0031016//pancreas development;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070848//response to growth factor;GO:0110024//positive regulation of cardiac muscle myoblast proliferation"	Homeobox
ENSG00000134146	3.961	2.224	3.924	3.378	3.327	4.07	138	91	115	100	108	95	DPH6	diphthamine biosynthesis 6 [Source:HGNC Symbol;Acc:HGNC:30543]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0017178//diphthine-ammonia ligase activity	GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine	--
ENSG00000134152	6.165	5.478	6.074	4.836	5.026	8.288	264	225	174	150	174	184	KATNBL1	katanin regulatory subunit B1 like 1 [Source:HGNC Symbol;Acc:HGNC:26199]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0051495//positive regulation of cytoskeleton organization	--
ENSG00000134153	54.39	53.062	54.115	55.127	50.996	59.07	1206	1180	880	899	949	953	EMC7	ER membrane protein complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:24301]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0032977//membrane insertase activity	GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000134160	110.726	100.118	112.564	115.403	124.572	145.039	5837	5291	4002	4157	5410	4311	TRPM1	transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007601//visual perception;GO:0016048//detection of temperature stimulus;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0050951//sensory perception of temperature stimulus;GO:0051262//protein tetramerization;GO:0055085//transmembrane transport;GO:0060402//calcium ion transport into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0071482//cellular response to light stimulus;GO:0098655//cation transmembrane transport	--
ENSG00000134183	0.127	0.325	0	0	0	0	4	9	0	0	0	0	GNAT2	G protein subunit alpha transducin 2 [Source:HGNC Symbol;Acc:HGNC:4394]	Organismal Systems	Sensory system	ko04744//Phototransduction	K04631	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009642//response to light intensity;GO:0046549//retinal cone cell development;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception	--
ENSG00000134184	44.581	50.764	45.981	62.127	53.31	53.179	1053.49	1209.9	804.75	1081.5	1077.2	911.73	GSTM1	glutathione S-transferase mu 1 [Source:HGNC Symbol;Acc:HGNC:4632]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006749//glutathione metabolic process;GO:0018916//nitrobenzene metabolic process;GO:0042178//xenobiotic catabolic process;GO:0051122//hepoxilin biosynthetic process;GO:0070458//cellular detoxification of nitrogen compound;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000134186	4.629	4.234	4.511	2.61	4.253	4.626	340	339	259	137	252	264	PRPF38B	pre-mRNA processing factor 38B [Source:HGNC Symbol;Acc:HGNC:25512]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12850	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0071011//precatalytic spliceosome	GO:0003723//RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000134193	0	0	0	0	0	0	0	0	0	0	0	0	REG4	regenerating family member 4 [Source:HGNC Symbol;Acc:HGNC:22977]	Human Diseases	Cancer: specific types	ko05226//Gastric cancer	K22244	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0008201//heparin binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:2001065//mannan binding	GO:0009617//response to bacterium	--
ENSG00000134198	2.368	2.628	2.384	1.594	1.777	1.964	133	145	67	67	92	78	TSPAN2	tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath	GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0007420//brain development;GO:0014002//astrocyte development;GO:0014005//microglia development;GO:0042552//myelination;GO:0048709//oligodendrocyte differentiation;GO:0061564//axon development	--
ENSG00000134200	0	0	0	0	0	0	0	0	0	0	0	0	TSHB	thyroid stimulating hormone subunit beta [Source:HGNC Symbol;Acc:HGNC:12372]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune disease;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05320//Autoimmune thyroid disease;ko04918//Thyroid hormone synthesis;ko04923//Regulation of lipolysis in adipocytes	K05251;K05251;K05251;K05251;K05251	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005179//hormone activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009653//anatomical structure morphogenesis;GO:0033189//response to vitamin A;GO:0043627//response to estrogen;GO:0051592//response to calcium ion	--
ENSG00000134201	1.249	0.737	1.43	1.602	1.799	1.352	30	24	18	29	39	28	GSTM5	glutathione S-transferase mu 5 [Source:HGNC Symbol;Acc:HGNC:4637]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0006749//glutathione metabolic process;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000134202	10.796	10.207	13.084	14.462	11.847	12.97	906	861	811	899	840	792	GSTM3	glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035686//sperm fibrous sheath;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding	GO:0006749//glutathione metabolic process;GO:0008065//establishment of blood-nerve barrier;GO:0018916//nitrobenzene metabolic process;GO:0042178//xenobiotic catabolic process;GO:0043627//response to estrogen;GO:0070458//cellular detoxification of nitrogen compound;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000134207	0	0	0	0	0	0	0	0	0	0	0	0	SYT6	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0070382//exocytic vesicle;GO:0097038//perinuclear endoplasmic reticulum	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0007340//acrosome reaction;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0060478//acrosomal vesicle exocytosis;GO:0071277//cellular response to calcium ion	--
ENSG00000134215	5.875	3.515	4.329	3.74	3.884	4.084	432	343	288	280	342	304	VAV3	vav guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:12659]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system	ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway	K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0006906//vesicle fusion;GO:0006974//cellular response to DNA damage stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0008361//regulation of cell size;GO:0009410//response to xenobiotic stimulus;GO:0016477//cell migration;GO:0030031//cell projection assembly;GO:0030032//lamellipodium assembly;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0030890//positive regulation of B cell proliferation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045785//positive regulation of cell adhesion;GO:0050790//regulation of catalytic activity;GO:0050853//B cell receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000134216	0	0	0	0	0	0	0	0	0	0	0	0	CHIA	chitinase acidic [Source:HGNC Symbol;Acc:HGNC:17432]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01183;K01183	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004568//chitinase activity;GO:0005515//protein binding;GO:0008061//chitin binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019900//kinase binding"	GO:0000272//polysaccharide catabolic process;GO:0002376//immune system process;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0005975//carbohydrate metabolic process;GO:0006030//chitin metabolic process;GO:0006032//chitin catabolic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0032722//positive regulation of chemokine production;GO:0044245//polysaccharide digestion	--
ENSG00000134222	2.826	3.742	3.422	2.618	2.553	4.031	98	93	71	66	71	92	PSRC1	proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472]	-	-	-	-	GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0008017//microtubule binding	"GO:0001578//microtubule bundle formation;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0030308//negative regulation of cell growth;GO:0031116//positive regulation of microtubule polymerization;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization"	--
ENSG00000134240	2.041	1.609	4.378	4.039	4.306	4.63	103	74	155	151	176	170	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 [Source:HGNC Symbol;Acc:HGNC:5008]	Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Amino acid metabolism;Carbohydrate metabolism;Metabolism of terpenoids and polyketides	"ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism;ko00900//Terpenoid backbone biosynthesis"	K01641;K01641;K01641;K01641;K01641	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004421//hydroxymethylglutaryl-CoA synthase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding	"GO:0001822//kidney development;GO:0001889//liver development;GO:0006084//acetyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0007420//brain development;GO:0007494//midgut development;GO:0007584//response to nutrient;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0009266//response to temperature stimulus;GO:0009410//response to xenobiotic stimulus;GO:0009617//response to bacterium;GO:0010038//response to metal ion;GO:0010142//farnesyl diphosphate biosynthetic process, mevalonate pathway;GO:0014070//response to organic cyclic compound;GO:0016126//sterol biosynthetic process;GO:0030324//lung development;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0032870//cellular response to hormone stimulus;GO:0033555//multicellular organismal response to stress;GO:0033574//response to testosterone;GO:0033762//response to glucagon;GO:0034014//response to triglyceride;GO:0034284//response to monosaccharide;GO:0034696//response to prostaglandin F;GO:0042594//response to starvation;GO:0043434//response to peptide hormone;GO:0045471//response to ethanol;GO:0046951//ketone body biosynthetic process;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0060416//response to growth hormone;GO:0060612//adipose tissue development;GO:0070542//response to fatty acid;GO:0070543//response to linoleic acid;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071398//cellular response to fatty acid;GO:0071407//cellular response to organic cyclic compound"	--
ENSG00000134242	0	0	0	0	0	0	0	0	0	0	0	0	PTPN22	protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0019900//kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:1990782//protein tyrosine kinase binding	"GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002685//regulation of leukocyte migration;GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006914//autophagy;GO:0010507//negative regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016311//dephosphorylation;GO:0030217//T cell differentiation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0032715//negative regulation of interleukin-6 production;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032817//regulation of natural killer cell proliferation;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035644//phosphoanandamide dephosphorylation;GO:0042307//positive regulation of protein import into nucleus;GO:0043508//negative regulation of JUN kinase activity;GO:0045088//regulation of innate immune response;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0050855//regulation of B cell receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070433//negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071225//cellular response to muramyl dipeptide;GO:0071663//positive regulation of granzyme B production;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1903169//regulation of calcium ion transmembrane transport;GO:1903753//negative regulation of p38MAPK cascade;GO:2000566//positive regulation of CD8-positive, alpha-beta T cell proliferation"	--
ENSG00000134243	58.983	58.808	57.838	51.487	54.358	58.495	8428	8571	6194	5530	6659	6126	SORT1	sortilin 1 [Source:HGNC Symbol;Acc:HGNC:11186]	Cellular Processes;Organismal Systems;Organismal Systems	Transport and catabolism;Nervous system;Digestive system	ko04142//Lysosome;ko04722//Neurotrophin signaling pathway;ko04979//Cholesterol metabolism	K12388;K12388;K12388	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0032580//Golgi cisterna membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0005515//protein binding;GO:0010465//nerve growth factor receptor activity;GO:0019899//enzyme binding;GO:0030379//neurotensin receptor activity, non-G protein-coupled;GO:0048406//nerve growth factor binding;GO:1905394//retromer complex binding"	GO:0001503//ossification;GO:0006622//protein targeting to lysosome;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006895//Golgi to endosome transport;GO:0006897//endocytosis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008333//endosome to lysosome transport;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010468//regulation of gene expression;GO:0014902//myotube differentiation;GO:0016050//vesicle organization;GO:0030154//cell differentiation;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0032868//response to insulin;GO:0038180//nerve growth factor signaling pathway;GO:0045599//negative regulation of fat cell differentiation;GO:0046323//glucose import;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048227//plasma membrane to endosome transport;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0090160//Golgi to lysosome transport	--
ENSG00000134245	7.684	6.906	6.825	10.851	10.596	9.039	1621.6	1358.69	834.42	1484.85	1873.09	1236.41	WNT2B	Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182;K00182	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity	GO:0002062//chondrocyte differentiation;GO:0002088//lens development in camera-type eye;GO:0007275//multicellular organism development;GO:0008584//male gonad development;GO:0009267//cellular response to starvation;GO:0016055//Wnt signaling pathway;GO:0021871//forebrain regionalization;GO:0030182//neuron differentiation;GO:0045165//cell fate commitment;GO:0060070//canonical Wnt signaling pathway;GO:0060492//lung induction;GO:0060638//mesenchymal-epithelial cell signaling;GO:0061072//iris morphogenesis;GO:0061303//cornea development in camera-type eye;GO:0071425//hematopoietic stem cell proliferation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis	--
ENSG00000134247	10.194	11.775	11.197	11.329	11.984	11.124	1335	1550	1083	1099	1326	1060	PTGFRN	prostaglandin F2 receptor inhibitor [Source:HGNC Symbol;Acc:HGNC:9601]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0014905//myoblast fusion involved in skeletal muscle regeneration;GO:0034389//lipid droplet organization	--
ENSG00000134248	60.328	72.967	71.888	71.326	55.263	71.304	786	956	688	689	611	682	LAMTOR5	"late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K16344	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0071986//Ragulator complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0008361//regulation of cell size;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0019079//viral genome replication;GO:0032008//positive regulation of TOR signaling;GO:0032757//positive regulation of interleukin-8 production;GO:0038202//TORC1 signaling;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0061462//protein localization to lysosome;GO:0071230//cellular response to amino acid stimulus;GO:1900182//positive regulation of protein localization to nucleus;GO:1904263//positive regulation of TORC1 signaling;GO:1905636//positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	--
ENSG00000134249	0	0	0	0	0	0	0	0	0	0	0	0	ADAM30	ADAM metallopeptidase domain 30 [Source:HGNC Symbol;Acc:HGNC:208]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:1990913//sperm head plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000134250	57.881	60.129	63.617	53.766	60.452	59.003	13604.9	14188.61	10961.25	9238.87	11989.88	10013.79	NOTCH2	notch receptor 2 [Source:HGNC Symbol;Acc:HGNC:7882]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0038023//signaling receptor activity;GO:0051059//NF-kappaB binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001709//cell fate determination;GO:0001889//liver development;GO:0001890//placenta development;GO:0001947//heart looping;GO:0002011//morphogenesis of an epithelial sheet;GO:0002315//marginal zone B cell differentiation;GO:0002437//inflammatory response to antigenic stimulus;GO:0003162//atrioventricular node development;GO:0003184//pulmonary valve morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010629//negative regulation of gene expression;GO:0010838//positive regulation of keratinocyte proliferation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0035264//multicellular organism growth;GO:0035622//intrahepatic bile duct development;GO:0042060//wound healing;GO:0042742//defense response to bacterium;GO:0043011//myeloid dendritic cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045672//positive regulation of osteoclast differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0046849//bone remodeling;GO:0050793//regulation of developmental process;GO:0060413//atrial septum morphogenesis;GO:0060674//placenta blood vessel development;GO:0061073//ciliary body morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070986//left/right axis specification;GO:0071228//cellular response to tumor cell;GO:0072014//proximal tubule development;GO:0072015//glomerular visceral epithelial cell development;GO:0072104//glomerular capillary formation;GO:0072574//hepatocyte proliferation;GO:0072576//liver morphogenesis;GO:1990705//cholangiocyte proliferation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2001204//regulation of osteoclast development"	--
ENSG00000134253	2.609	1.691	1.292	1.682	1.5	2.808	143	105	70	86	82	108	TRIM45	tripartite motif containing 45 [Source:HGNC Symbol;Acc:HGNC:19018]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060348//bone development"	--
ENSG00000134255	10.909	9.841	11.6	10.091	9.601	12.622	499	452	392	342	371	420	CEPT1	choline/ethanolamine phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24289]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K13644;K13644;K13644;K13644	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	"GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0004307//ethanolaminephosphotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0046872//metal ion binding;GO:0047359//1-alkenyl-2-acylglycerol choline phosphotransferase activity"	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0008654//phospholipid biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000134256	0.103	0.081	0.06	0.04	0.139	0.101	7	6	3	2	8	5	CD101	CD101 molecule [Source:HGNC Symbol;Acc:HGNC:5949]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"	GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000134258	0.042	0.021	0	0.057	0.044	0.058	2	1	0	2	2	2	VTCN1	V-set domain containing T cell activation inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:28873]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06747	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005102//signaling receptor binding	GO:0001562//response to protozoan;GO:0001817//regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0032743//positive regulation of interleukin-2 production;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0050852//T cell receptor signaling pathway;GO:0050868//negative regulation of T cell activation	--
ENSG00000134259	2.187	2.32	1.83	1.411	1.9	1.197	51	53	31	25	37	22	NGF	nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Signaling molecules and interaction;Signal transduction;Signal transduction;Cell growth and death;Nervous system;Sensory system	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04210//Apoptosis;ko04722//Neurotrophin signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels	K02582;K02582;K02582;K02582;K02582;K02582;K02582;K02582;K02582	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031904//endosome lumen	GO:0004857//enzyme inhibitor activity;GO:0005102//signaling receptor binding;GO:0005163//nerve growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008289//lipid binding;GO:0030414//peptidase inhibitor activity	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007422//peripheral nervous system development;GO:0007613//memory;GO:0008285//negative regulation of cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010466//negative regulation of peptidase activity;GO:0010628//positive regulation of gene expression;GO:0010951//negative regulation of endopeptidase activity;GO:0021675//nerve development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038180//nerve growth factor signaling pathway;GO:0043388//positive regulation of DNA binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048672//positive regulation of collateral sprouting;GO:0048812//neuron projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission	--
ENSG00000134262	3.741	3.334	3.228	3.763	3.371	2.982	198	192	130	160	165	124	AP4B1	adaptor related protein complex 4 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:572]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12401	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030117//membrane coat;GO:0030124//AP-4 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0031904//endosome lumen;GO:0032588//trans-Golgi network membrane;GO:0097708//intracellular vesicle	GO:0005515//protein binding;GO:0030276//clathrin binding	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000134265	3.214	2.992	3.741	3.011	2.93	3.927	235	222	193	158	161	200	NAPG	NSF attachment protein gamma [Source:HGNC Symbol;Acc:HGNC:7642]	-	-	-	-	GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0031201//SNARE complex;GO:0070062//extracellular exosome	GO:0005483//soluble NSF attachment protein activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050821//protein stabilization;GO:0061025//membrane fusion;GO:0065003//protein-containing complex assembly	--
ENSG00000134278	21.822	16.928	18.46	16.709	19.032	19.751	2228	1858	1433	1268	1569	1463	SPIRE1	spire type actin nucleation factor 1 [Source:HGNC Symbol;Acc:HGNC:30622]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0022607//cellular component assembly;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0036089//cleavage furrow formation;GO:0040038//polar body extrusion after meiotic divisions;GO:0045010//actin nucleation;GO:0046907//intracellular transport;GO:0048193//Golgi vesicle transport;GO:0051234//establishment of localization;GO:0051295//establishment of meiotic spindle localization;GO:0051639//actin filament network formation;GO:0051641//cellular localization;GO:0070649//formin-nucleated actin cable assembly;GO:0090141//positive regulation of mitochondrial fission;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000134283	14.917	16.559	17.845	11.806	11.387	13.916	574.27	568.42	463.79	325.29	390.01	396	PPHLN1	periphilin 1 [Source:HGNC Symbol;Acc:HGNC:19369]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0031424//keratinization;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly;GO:0097355//protein localization to heterochromatin"	--
ENSG00000134285	3.773	4.293	2.324	2.878	4.429	2.612	65	74	30	36	65	34	FKBP11	FKBP prolyl isomerase 11 [Source:HGNC Symbol;Acc:HGNC:18624]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding	--
ENSG00000134287	70.607	50.588	62.653	74.24	62.625	73.795	4484.39	4246.85	3324.99	3645.04	4118.06	3609	ARF3	ADP ribosylation factor 3 [Source:HGNC Symbol;Acc:HGNC:654]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07938	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport"	--
ENSG00000134291	77.767	62.292	75.5	65.603	60.353	60.187	1660	1535	1244	1128	1177	1017	TMEM106C	transmembrane protein 106C [Source:HGNC Symbol;Acc:HGNC:28775]	-	-	-	-	GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000134294	41.228	28.703	30.045	24.9	26.448	51.029	3739	2830	2113	1671	1931	3370	SLC38A2	solute carrier family 38 member 2 [Source:HGNC Symbol;Acc:HGNC:13448]	Organismal Systems;Organismal Systems;Organismal Systems	Nervous system;Digestive system;Nervous system	ko04724//Glutamatergic synapse;ko04974//Protein digestion and absorption;ko04727//GABAergic synapse	K14207;K14207;K14207	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0043025//neuronal cell body	GO:0005295//neutral amino acid:sodium symporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0006868//glutamine transport;GO:0007565//female pregnancy;GO:0010628//positive regulation of gene expression;GO:0015804//neutral amino acid transport;GO:0015825//L-serine transport;GO:0021987//cerebral cortex development;GO:0031460//glycine betaine transport;GO:0032328//alanine transport;GO:0033120//positive regulation of RNA splicing;GO:0034198//cellular response to amino acid starvation;GO:0071260//cellular response to mechanical stimulus;GO:0080135//regulation of cellular response to stress;GO:0150104//transport across blood-brain barrier;GO:1903841//cellular response to arsenite(3-)	--
ENSG00000134308	141.819	134.793	130.638	123.673	119.786	121.702	6421	6164	4395	4173	4571	4034	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta [Source:HGNC Symbol;Acc:HGNC:12854]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle	K16197;K16197;K16197;K16197;K16197;K16197;K16197	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0047485//protein N-terminus binding	"GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0021762//substantia nigra development;GO:0034613//cellular protein localization;GO:0045892//negative regulation of transcription, DNA-templated;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway"	--
ENSG00000134313	32.817	28.407	27.68	21.542	24.339	26.798	4914	4277	3064	2397	3021	2913	KIDINS220	kinase D interacting substrate 220 [Source:HGNC Symbol;Acc:HGNC:29508]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12460	GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0019887//protein kinase regulator activity;GO:0030165//PDZ domain binding	GO:0001701//in utero embryonic development;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development;GO:0038180//nerve growth factor signaling pathway;GO:0048813//dendrite morphogenesis;GO:0050790//regulation of catalytic activity;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000134317	1.108	0.654	1.247	0.765	0.566	0.691	34	39	18	14	22	21	GRHL1	grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0002934//desmosome organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008544//epidermis development;GO:0045616//regulation of keratinocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061436//establishment of skin barrier	CP2
ENSG00000134318	1.886	1.306	1.166	0.859	1.04	1.817	264	196	123	103	142	148	ROCK2	Rho associated coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:10252]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cell motility;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Signal transduction;Endocrine system;Circulatory system;Immune system;Signal transduction;Immune system	ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration	K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388;K17388	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0072518//Rho-dependent protein serine/threonine kinase activity;GO:0106310//protein serine kinase activity	GO:0000281//mitotic cytokinesis;GO:0001837//epithelial to mesenchymal transition;GO:0001934//positive regulation of protein phosphorylation;GO:0002931//response to ischemia;GO:0003180//aortic valve morphogenesis;GO:0006468//protein phosphorylation;GO:0006939//smooth muscle contraction;GO:0006996//organelle organization;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007266//Rho protein signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010825//positive regulation of centrosome duplication;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030155//regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0031644//regulation of nervous system process;GO:0032723//positive regulation of connective tissue growth factor production;GO:0032956//regulation of actin cytoskeleton organization;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0039694//viral RNA genome replication;GO:0042752//regulation of circadian rhythm;GO:0043410//positive regulation of MAPK cascade;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045616//regulation of keratinocyte differentiation;GO:0048511//rhythmic process;GO:0048598//embryonic morphogenesis;GO:0051246//regulation of protein metabolic process;GO:0051298//centrosome duplication;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051893//regulation of focal adhesion assembly;GO:0061157//mRNA destabilization;GO:0070168//negative regulation of biomineral tissue development;GO:0071394//cellular response to testosterone stimulus;GO:0071559//response to transforming growth factor beta;GO:0072659//protein localization to plasma membrane;GO:0090271//positive regulation of fibroblast growth factor production;GO:0097746//blood vessel diameter maintenance;GO:0110061//regulation of angiotensin-activated signaling pathway;GO:0150033//negative regulation of protein localization to lysosome;GO:1900037//regulation of cellular response to hypoxia;GO:1901888//regulation of cell junction assembly;GO:1902004//positive regulation of amyloid-beta formation;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902966//positive regulation of protein localization to early endosome;GO:1902993//positive regulation of amyloid precursor protein catabolic process;GO:1903140//regulation of establishment of endothelial barrier;GO:1903347//negative regulation of bicellular tight junction assembly;GO:1905145//cellular response to acetylcholine;GO:1905205//positive regulation of connective tissue replacement;GO:1990776//response to angiotensin;GO:2000114//regulation of establishment of cell polarity;GO:2000145//regulation of cell motility	--
ENSG00000134321	1.65	1.899	2.381	1.69	1.622	2.17	143	141	127	92	105	111	RSAD2	radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908]	Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral	ko05164//Influenza A;ko05160//Hepatitis C	K15045;K15045	GO:0001650//fibrillar center;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0016020//membrane	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0002376//immune system process;GO:0009615//response to virus;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0050709//negative regulation of protein secretion;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus;GO:2000553//positive regulation of T-helper 2 cell cytokine production"	--
ENSG00000134323	0.757	1.177	0.849	2.293	2.175	1.965	37	50	34	92	91	72	MYCN	"MYCN proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7559]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09109	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA"	bHLH
ENSG00000134324	10.176	10.482	11.177	10.401	10.141	13.129	1077	1096	830	800	894	999	LPIN1	lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine and metabolic disease;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04150//mTOR signaling pathway;ko04936//Alcoholic liver disease;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K15728;K15728;K15728;K15728;K15728	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006642//triglyceride mobilization;GO:0006654//phosphatidic acid biosynthetic process;GO:0007077//mitotic nuclear membrane disassembly;GO:0009062//fatty acid catabolic process;GO:0016311//dephosphorylation;GO:0019432//triglyceride biosynthetic process;GO:0031100//animal organ regeneration;GO:0031642//negative regulation of myelination;GO:0032869//cellular response to insulin stimulus;GO:0044255//cellular lipid metabolic process;GO:0045740//positive regulation of DNA replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046473//phosphatidic acid metabolic process;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1903741//negative regulation of phosphatidate phosphatase activity	--
ENSG00000134326	1.137	1.512	2.049	1.535	1.936	1.525	73	95	96	73	105	68	CMPK2	cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K13809;K13809	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004798//thymidylate kinase activity;GO:0005524//ATP binding;GO:0009041//uridylate kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0033862//UMP kinase activity;GO:0036430//CMP kinase activity;GO:0036431//dCMP kinase activity;GO:0050145//nucleoside monophosphate kinase activity	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006227//dUDP biosynthetic process;GO:0006233//dTDP biosynthetic process;GO:0006235//dTTP biosynthetic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0046940//nucleoside monophosphate phosphorylation;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000134330	14.13	14.958	14.525	14.56	10.501	15.356	364.25	382.81	262.6	254.65	228.84	267.14	IAH1	isoamyl acetate hydrolyzing esterase 1 (putative) [Source:HGNC Symbol;Acc:HGNC:27696]	-	-	-	-	-	GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process	--
ENSG00000134333	253.155	261.597	208.085	197.681	216.516	137.491	8455	9271	5244	4874	6215	3561	LDHA	lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:1990204//oxidoreductase complex	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0045296//cadherin binding"	GO:0006089//lactate metabolic process;GO:0006090//pyruvate metabolic process;GO:0006096//glycolytic process;GO:0019752//carboxylic acid metabolic process;GO:0021762//substantia nigra development;GO:0032787//monocarboxylic acid metabolic process	--
ENSG00000134339	0	0.083	0	0.454	0.099	0	0	1	0	5	1	0	SAA2	serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514]	-	-	-	-	GO:0005576//extracellular region;GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006953//acute-phase response	--
ENSG00000134343	0.227	0.33	0.186	0.121	0.236	0.155	28	26	13	11	18	13	ANO3	anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0017128//phospholipid scramblase activity;GO:0046983//protein dimerization activity	GO:0006869//lipid transport;GO:0016048//detection of temperature stimulus;GO:0034220//ion transmembrane transport;GO:0050982//detection of mechanical stimulus;GO:0055085//transmembrane transport;GO:0061588//calcium activated phospholipid scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling;GO:0061591//calcium activated galactosylceramide scrambling;GO:1902476//chloride transmembrane transport	--
ENSG00000134352	42.997	26.564	28.131	20.747	24.768	27.493	5735	3731	2789	2042	2713	2788	IL6ST	interleukin 6 cytokine family signal transducer [Source:HGNC Symbol;Acc:HGNC:6021]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Signaling molecules and interaction;Cancer: overview;Infectious disease: viral;Signal transduction;Cellular community - eukaryotes;Immune system;Signaling molecules and interaction	ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04630//JAK-STAT signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05060;K05060;K05060;K05060;K05060;K05060;K05060;K05060;K05060	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005896//interleukin-6 receptor complex;GO:0005900//oncostatin-M receptor complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0044297//cell body;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0070110//ciliary neurotrophic factor receptor complex	GO:0004896//cytokine receptor activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0004915//interleukin-6 receptor activity;GO:0004921//interleukin-11 receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0019955//cytokine binding;GO:0019970//interleukin-11 binding;GO:0019981//interleukin-6 binding;GO:0042802//identical protein binding;GO:0045509//interleukin-27 receptor activity;GO:0097110//scaffold protein binding	GO:0002675//positive regulation of acute inflammatory response;GO:0002821//positive regulation of adaptive immune response;GO:0005977//glycogen metabolic process;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008593//regulation of Notch signaling pathway;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0019221//cytokine-mediated signaling pathway;GO:0034097//response to cytokine;GO:0038154//interleukin-11-mediated signaling pathway;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0048711//positive regulation of astrocyte differentiation;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0060576//intestinal epithelial cell development;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070104//negative regulation of interleukin-6-mediated signaling pathway;GO:0070106//interleukin-27-mediated signaling pathway;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:1901731//positive regulation of platelet aggregation	--
ENSG00000134363	0.189	0.271	0.124	0.283	0.124	0.231	9	13	2	10	5	8	FST	follistatin [Source:HGNC Symbol;Acc:HGNC:3971]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K04661	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0038102//activin receptor antagonist activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0048185//activin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007276//gamete generation;GO:0007389//pattern specification process;GO:0008585//female gonad development;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043616//keratinocyte proliferation;GO:0045596//negative regulation of cell differentiation;GO:0051798//positive regulation of hair follicle development	--
ENSG00000134365	0	0	0	0.05	0	0	0	0	0	1	0	0	CFHR4	complement factor H related 4 [Source:HGNC Symbol;Acc:HGNC:16979]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K23816	GO:0005576//extracellular region	GO:0005319//lipid transporter activity;GO:0005515//protein binding	GO:0006869//lipid transport	--
ENSG00000134369	18.851	19.203	14.804	13.468	16.308	13.401	2917	3043	1995	1634	2130	1553	NAV1	neuron navigator 1 [Source:HGNC Symbol;Acc:HGNC:15989]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0043194//axon initial segment	-	GO:0001578//microtubule bundle formation;GO:0001764//neuron migration;GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0030154//cell differentiation	--
ENSG00000134371	10.77	8.298	7.922	7.605	7.989	8.484	918	670	495	449	514	519	CDC73	cell division cycle 73 [Source:HGNC Symbol;Acc:HGNC:16783]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016593//Cdc73/Paf1 complex"	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0001711//endodermal cell fate commitment;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006378//mRNA polyadenylation;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010390//histone monoubiquitination;GO:0016055//Wnt signaling pathway;GO:0016570//histone modification;GO:0019827//stem cell population maintenance;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0031648//protein destabilization;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033523//histone H2B ubiquitination;GO:0034402//recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex;GO:0043066//negative regulation of apoptotic process;GO:0045638//negative regulation of myeloid cell differentiation;GO:0048147//negative regulation of fibroblast proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000134375	24.281	22.994	26.704	25.127	20.924	27.187	831	791	675	637	605	677	TIMM17A	translocase of inner mitochondrial membrane 17A [Source:HGNC Symbol;Acc:HGNC:17315]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0008320//protein transmembrane transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000134376	1.446	1.905	2.192	2.073	1.669	1.634	147	189	166	140	145	120	CRB1	crumbs cell polarity complex component 1 [Source:HGNC Symbol;Acc:HGNC:2343]	Environmental Information Processing	Signal transduction	ko04390//Hippo signaling pathway	K16681	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032991//protein-containing complex;GO:0035003//subapical complex;GO:0042995//cell projection;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0097386//glial cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0001974//blood vessel remodeling;GO:0007009//plasma membrane organization;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007163//establishment or maintenance of cell polarity;GO:0007267//cell-cell signaling;GO:0007601//visual perception;GO:0010001//glial cell differentiation;GO:0010467//gene expression;GO:0010842//retina layer formation;GO:0034613//cellular protein localization;GO:0035845//photoreceptor cell outer segment organization;GO:0042462//eye photoreceptor cell development;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045494//photoreceptor cell maintenance;GO:0050908//detection of light stimulus involved in visual perception;GO:0060041//retina development in camera-type eye;GO:0060042//retina morphogenesis in camera-type eye;GO:0060060//post-embryonic retina morphogenesis in camera-type eye;GO:0061024//membrane organization;GO:0061159//establishment of bipolar cell polarity involved in cell morphogenesis;GO:0071482//cellular response to light stimulus	--
ENSG00000134389	0	0	0	0	0	0	0	0	0	0	0	0	CFHR5	complement factor H related 5 [Source:HGNC Symbol;Acc:HGNC:24668]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K23817	GO:0005576//extracellular region;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	"GO:0006957//complement activation, alternative pathway;GO:0032091//negative regulation of protein binding;GO:0051838//cytolysis by host of symbiont cells"	--
ENSG00000134398	0	0.091	0	0	0	0	0	3	0	0	0	0	ERN2	endoplasmic reticulum to nucleus signaling 2 [Source:HGNC Symbol;Acc:HGNC:16942]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:1990604//IRE1-TRAF2-ASK1 complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004540//ribonuclease activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0106310//protein serine kinase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0008152//metabolic process;GO:0010468//regulation of gene expression;GO:0016075//rRNA catabolic process;GO:0016310//phosphorylation;GO:0030263//apoptotic chromosome condensation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034976//response to endoplasmic reticulum stress;GO:0036498//IRE1-mediated unfolded protein response;GO:0043507//positive regulation of JUN kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051252//regulation of RNA metabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000134419	396.219	423.469	415.674	418.061	330.692	345.804	4484.85	4792.95	3485.94	3501.92	3174.92	2862.8	RPS15A	ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02957;K02957	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0008284//positive regulation of cell population proliferation;GO:0009615//response to virus;GO:0045787//positive regulation of cell cycle	--
ENSG00000134438	10.239	10.534	14.362	12.367	12.548	14.133	688	710	705	606	706	681	RAX	retina and anterior neural fold homeobox [Source:HGNC Symbol;Acc:HGNC:18662]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007420//brain development;GO:0007601//visual perception;GO:0021854//hypothalamus development;GO:0043010//camera-type eye development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060173//limb development"	Homeobox
ENSG00000134440	62.118	58.851	56.945	51.81	54.284	63.428	3550	3374	2397	1971	2545	2492	NARS1	asparaginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7643]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01893	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004816//asparagine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0031728//CCR3 chemokine receptor binding;GO:0046983//protein dimerization activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006421//asparaginyl-tRNA aminoacylation;GO:0016477//cell migration;GO:0021987//cerebral cortex development	--
ENSG00000134443	0	0	0	0	0	0	0	0	0	0	0	0	GRP	gastrin releasing peptide [Source:HGNC Symbol;Acc:HGNC:4605]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05224	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen	GO:0005102//signaling receptor binding;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0090277//positive regulation of peptide hormone secretion;GO:1900738//positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	--
ENSG00000134444	9.793	7.384	9.16	7.189	8.561	9.162	766	698	534	465	577	514	RELCH	"RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing [Source:HGNC Symbol;Acc:HGNC:29289]"	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0006869//lipid transport;GO:0032367//intracellular cholesterol transport	--
ENSG00000134452	19.532	20.172	21.652	18.736	20.264	19.764	1440	1497	1182	1025	1265	1060	FBH1	F-box DNA helicase 1 [Source:HGNC Symbol;Acc:HGNC:13620]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0019005//SCF ubiquitin ligase complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015616//DNA translocase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043138//3'-5' DNA helicase activity	"GO:0000724//double-strand break repair via homologous recombination;GO:0000725//recombinational repair;GO:0000737//DNA catabolic process, endonucleolytic;GO:0001934//positive regulation of protein phosphorylation;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008219//cell death;GO:0016567//protein ubiquitination;GO:0031297//replication fork processing;GO:0032508//DNA duplex unwinding;GO:0035562//negative regulation of chromatin binding;GO:0048478//replication fork protection;GO:0072429//response to intra-S DNA damage checkpoint signaling;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:2000042//negative regulation of double-strand break repair via homologous recombination"	--
ENSG00000134453	21.978	20.657	22.32	19.778	19.131	18.419	760	734	580	515	534	479	RBM17	RNA binding motif protein 17 [Source:HGNC Symbol;Acc:HGNC:16944]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12840	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000134460	0	0	0	0	0	0	0	0	0	0	0	0	IL2RA	interleukin 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6008]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Immune system;Signal transduction;Infectious disease: viral;Immune system;Signaling molecules and interaction;Immune system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04658//Th1 and Th2 cell differentiation	K05068;K05068;K05068;K05068;K05068;K05068;K05068;K05068;K05068;K05068;K05068	GO:0005886//plasma membrane;GO:0005893//interleukin-2 receptor complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004911//interleukin-2 receptor activity;GO:0005515//protein binding;GO:0019976//interleukin-2 binding	GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0002664//regulation of T cell tolerance induction;GO:0006915//apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0038110//interleukin-2-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0043029//T cell homeostasis;GO:0045582//positive regulation of T cell differentiation;GO:0046013//regulation of T cell homeostatic proliferation;GO:0050672//negative regulation of lymphocyte proliferation;GO:0050728//negative regulation of inflammatory response	--
ENSG00000134461	4.084	3.507	3.463	3.641	3.712	3.936	178	148	113	114	123	123	ANKRD16	ankyrin repeat domain 16 [Source:HGNC Symbol;Acc:HGNC:23471]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006400//tRNA modification	--
ENSG00000134463	13.64	13.364	14.975	13.591	13.489	10.996	462	455	367	341	386	271	ECHDC3	enoyl-CoA hydratase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23489]	-	-	-	-	GO:0005739//mitochondrion	GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity;GO:0016836//hydro-lyase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:1900078//positive regulation of cellular response to insulin stimulus	--
ENSG00000134470	0	0.061	0.35	0.166	0.146	0	0	2	3	3	4	0	IL15RA	interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Immune system	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04630//JAK-STAT signaling pathway;ko04672//Intestinal immune network for IgA production	K05074;K05074;K05074;K05074;K05074	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042010//interleukin-15 receptor activity	GO:0032825//positive regulation of natural killer cell differentiation;GO:0035723//interleukin-15-mediated signaling pathway;GO:0050766//positive regulation of phagocytosis	--
ENSG00000134480	14.191	11.889	12.475	8.726	12.059	11.158	396	327	253	182	281	221	CCNH	cyclin H [Source:HGNC Symbol;Acc:HGNC:1594]	Cellular Processes;Genetic Information Processing;Genetic Information Processing	Cell growth and death;Transcription;Replication and repair	ko04110//Cell cycle;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K06634;K06634;K06634	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005675//transcription factor TFIIH holo complex;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0070516//CAK-ERCC2 complex;GO:0070985//transcription factor TFIIK complex	GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007049//cell cycle;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:2000045//regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000134489	0	0.026	0.018	0	0	0	0	2	1	0	0	0	HRH4	histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04152	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004969//histamine receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0008150//biological_process;GO:0043408//regulation of MAPK cascade;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000134490	2.744	3.947	3.358	2.67	2.963	3.224	129	198	105	95	115	113	TMEM241	transmembrane protein 241 [Source:HGNC Symbol;Acc:HGNC:31723]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport	--
ENSG00000134504	5.604	6.19	7.189	6.742	8.536	7.928	286	345	261	290	304	337	KCTD1	potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0034451//centriolar satellite;GO:0045171//intercellular bridge	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042802//identical protein binding	"GO:0045892//negative regulation of transcription, DNA-templated;GO:0051260//protein homooligomerization"	--
ENSG00000134508	8.905	8.235	9.484	11.028	9.376	12.605	602	576	533	586	582	725	CABLES1	Cdk5 and Abl enzyme substrate 1 [Source:HGNC Symbol;Acc:HGNC:25097]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000134516	1.698	1.375	0.226	0.418	0.395	0.153	43	58	21	39	42	14	DOCK2	dedicator of cytokinesis 2 [Source:HGNC Symbol;Acc:HGNC:2988]	Organismal Systems	Immune system	ko04062//Chemokine signaling pathway	K12367	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042608//T cell receptor binding	GO:0001766//membrane raft polarization;GO:0001768//establishment of T cell polarity;GO:0001771//immunological synapse formation;GO:0002277//myeloid dendritic cell activation involved in immune response;GO:0006935//chemotaxis;GO:0007010//cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0030036//actin cytoskeleton organization;GO:0042098//T cell proliferation;GO:0042110//T cell activation;GO:0044351//macropinocytosis;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0046631//alpha-beta T cell activation;GO:0046633//alpha-beta T cell proliferation;GO:0050766//positive regulation of phagocytosis;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000134531	19.779	17.942	23.825	41.201	26.695	29.529	1807	1988	1688	2450	2379	1910	EMP1	epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008219//cell death;GO:0008544//epidermis development;GO:0032060//bleb assembly	--
ENSG00000134532	8.349	6.173	6.845	4.828	4.492	6.347	978	675	577	386	447	548	SOX5	SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	GO:0001502//cartilage condensation;GO:0002062//chondrocyte differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0045165//cell fate commitment;GO:0051216//cartilage development;GO:0055059//asymmetric neuroblast division;GO:0061036//positive regulation of cartilage development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000741//positive regulation of mesenchymal stem cell differentiation	HMG
ENSG00000134533	0.062	0.023	0	0.063	0.083	0.192	2	1	0	2	3	3	RERG	RAS like estrogen regulated growth inhibitor [Source:HGNC Symbol;Acc:HGNC:15980]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0030331//estrogen receptor binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0009725//response to hormone;GO:0030308//negative regulation of cell growth	--
ENSG00000134538	0.035	0	0.047	0.023	0	0	2	0	2	1	0	0	SLCO1B1	solute carrier organic anion transporter family member 1B1 [Source:HGNC Symbol;Acc:HGNC:10959]	Organismal Systems	Digestive system	ko04976//Bile secretion	K05043	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0042167//heme catabolic process;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport	--
ENSG00000134539	0.003	0	0.004	0.004	0.015	0.021	1	0	1	1	4	1	KLRD1	killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378]	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K06516;K06516;K06516	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	"GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0023024//MHC class I protein complex binding;GO:0023030//MHC class Ib protein binding, via antigen binding groove;GO:0030246//carbohydrate binding;GO:0062082//HLA-E specific inhibitory MHC class Ib receptor activity;GO:1990405//protein antigen binding"	GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002228//natural killer cell mediated immunity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0032814//regulation of natural killer cell activation;GO:0045087//innate immune response;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000134545	0	0	0	0	0	0	0	0	0	0	0	0	KLRC1	killer cell lectin like receptor C1 [Source:HGNC Symbol;Acc:HGNC:6374]	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K06541;K06541;K06541	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0023024//MHC class I protein complex binding;GO:0030246//carbohydrate binding;GO:0062082//HLA-E specific inhibitory MHC class Ib receptor activity	"GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002305//CD8-positive, gamma-delta intraepithelial T cell differentiation;GO:0002376//immune system process;GO:0002769//natural killer cell inhibitory signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0032814//regulation of natural killer cell activation;GO:0045087//innate immune response;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity"	--
ENSG00000134548	0.707	0.836	0.866	1.18	0.804	1.247	28	31	24	33	27	35	SPX	spexin hormone [Source:HGNC Symbol;Acc:HGNC:28139]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding	GO:0003084//positive regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0010459//negative regulation of heart rate;GO:0032099//negative regulation of appetite;GO:0035814//negative regulation of renal sodium excretion;GO:0044539//long-chain fatty acid import into cell;GO:0051930//regulation of sensory perception of pain;GO:1904306//positive regulation of gastro-intestinal system smooth muscle contraction	--
ENSG00000134551	0	0.117	0.041	0.346	0.089	0.022	0	1.57	2	4	1	1.04	PRH2	proline rich protein HaeIII subfamily 2 [Source:HGNC Symbol;Acc:HGNC:9367]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13910	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	-	--
ENSG00000134569	0.662	0.794	0.472	0.631	0.707	0.569	112	135	59	79	101	70	LRP4	LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0043025//neuronal cell body;GO:0044853//plasma membrane raft;GO:0097060//synaptic membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0034185//apolipoprotein binding;GO:0042803//protein homodimerization activity;GO:0097110//scaffold protein binding	GO:0001822//kidney development;GO:0001932//regulation of protein phosphorylation;GO:0001942//hair follicle development;GO:0006897//endocytosis;GO:0008104//protein localization;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030279//negative regulation of ossification;GO:0030326//embryonic limb morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0043113//receptor clustering;GO:0048699//generation of neurons;GO:0048813//dendrite morphogenesis;GO:0048856//anatomical structure development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050771//negative regulation of axonogenesis;GO:0050808//synapse organization;GO:0051124//synaptic assembly at neuromuscular junction;GO:0060173//limb development;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1901631//positive regulation of presynaptic membrane organization;GO:1904395//positive regulation of skeletal muscle acetylcholine-gated channel clustering	--
ENSG00000134571	0	0	0	0	0	0	0	0	0	0	0	0	MYBPC3	myosin binding protein C3 [Source:HGNC Symbol;Acc:HGNC:7551]	Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy	K12568;K12568	GO:0005829//cytosol;GO:0005863//striated muscle myosin thick filament;GO:0014705//C zone;GO:0030017//sarcomere;GO:0031672//A band;GO:0032982//myosin filament;GO:0097512//cardiac myofibril	GO:0001671//ATPase activator activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0017022//myosin binding;GO:0031432//titin binding;GO:0032036//myosin heavy chain binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0003007//heart morphogenesis;GO:0006942//regulation of striated muscle contraction;GO:0007155//cell adhesion;GO:0032781//positive regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000134574	1.842	2.252	1.697	2.314	1.777	4.146	59	63	44	48	41	66	DDB2	damage specific DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2718]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases	"Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Folding, sorting and degradation;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types;Replication and repair;Cancer: specific types"	ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko05224//Breast cancer;ko05226//Gastric cancer;ko04120//Ubiquitin mediated proteolysis;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko03420//Nucleotide excision repair;ko05216//Thyroid cancer	K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140;K10140	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006290//pyrimidine dimer repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0016567//protein ubiquitination;GO:0034644//cellular response to UV;GO:0035518//histone H2A monoubiquitination;GO:0051865//protein autoubiquitination;GO:0070914//UV-damage excision repair	--
ENSG00000134575	41.523	43.612	45.653	50.523	45.119	44.143	1793	1901	1476	1613	1667	1332	ACP2	"acid phosphatase 2, lysosomal [Source:HGNC Symbol;Acc:HGNC:123]"	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04142//Lysosome;ko00740//Riboflavin metabolism	K14410;K14410;K14410	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003993//acid phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0007040//lysosome organization;GO:0016311//dephosphorylation	--
ENSG00000134588	0	0	0	0	0	0	0	0	0	0	0	0	USP26	ubiquitin specific peptidase 26 [Source:HGNC Symbol;Acc:HGNC:13485]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000134590	57.271	63.095	64.565	71.038	69.177	62.258	1416	1568	1179	1301	1445	1120	RTL8C	retrotransposon Gag like 8C [Source:HGNC Symbol;Acc:HGNC:2569]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000134594	2.755	4.061	4.352	6.405	2.959	4.698	54	80	63	93	49	67	RAB33A	"RAB33A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9773]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0019882//antigen processing and presentation;GO:0032482//Rab protein signal transduction	--
ENSG00000134595	0	0	0	0	0	0	0	0	0	0	0	0	SOX3	SRY-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11199]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007417//central nervous system development;GO:0007423//sensory organ development;GO:0007530//sex determination;GO:0009653//anatomical structure morphogenesis;GO:0021854//hypothalamus development;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060324//face development"	HMG
ENSG00000134597	3.767	4.553	3.68	3.197	2.655	3.327	130	164	101	84	83	88	RBMX2	RNA binding motif protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:24282]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005686//U2 snRNP;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000134602	19.953	17.38	18.4	14.152	14.722	17.391	1299	1130	846	696	772	840	STK26	serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0009267//cellular response to starvation;GO:0016310//phosphorylation;GO:0030033//microvillus assembly;GO:0030336//negative regulation of cell migration;GO:0042542//response to hydrogen peroxide;GO:0042981//regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:1903205//regulation of hydrogen peroxide-induced cell death	--
ENSG00000134627	0.414	0.24	0.187	0.262	0.356	0.233	10	16.27	9	6	15	7	PIWIL4	piwi like RNA-mediated gene silencing 4 [Source:HGNC Symbol;Acc:HGNC:18444]	Organismal Systems	Development and regeneration	ko04320//Dorso-ventral axis formation	K02156	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043186//P granule;GO:0071547//piP-body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0034584//piRNA binding	GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0010669//epithelial structure maintenance;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000134640	0	0	0	0	0	0	0	0	0	0	0	0	MTNR1B	melatonin receptor 1B [Source:HGNC Symbol;Acc:HGNC:7464]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Environmental adaptation	ko04080//Neuroactive ligand-receptor interaction;ko04713//Circadian entrainment	K04286;K04286	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008502//melatonin receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0042593//glucose homeostasis;GO:0042753//positive regulation of circadian rhythm;GO:0043010//camera-type eye development;GO:0043524//negative regulation of neuron apoptotic process;GO:0045906//negative regulation of vasoconstriction;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:0046676//negative regulation of insulin secretion;GO:0050796//regulation of insulin secretion;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051970//negative regulation of transmission of nerve impulse;GO:0051971//positive regulation of transmission of nerve impulse;GO:0098908//regulation of neuronal action potential;GO:1902260//negative regulation of delayed rectifier potassium channel activity"	--
ENSG00000134644	30.447	27.968	26.736	25.131	27.832	28.394	2935	2770	1980	1878	2218	1991	PUM1	pumilio RNA binding family member 1 [Source:HGNC Symbol;Acc:HGNC:14957]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K17943	GO:0000932//P-body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035198//miRNA binding	GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0008344//adult locomotory behavior;GO:0010608//posttranscriptional regulation of gene expression;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0043488//regulation of mRNA stability;GO:0048863//stem cell differentiation;GO:0051726//regulation of cell cycle;GO:0051983//regulation of chromosome segregation;GO:0060964//regulation of gene silencing by miRNA;GO:0061157//mRNA destabilization;GO:1900246//positive regulation of RIG-I signaling pathway;GO:2000637//positive regulation of gene silencing by miRNA	--
ENSG00000134668	10.849	13.14	12.363	4.912	6.053	4.631	416	481	354	142	192	127	SPOCD1	SPOC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26338]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome	-	"GO:0006306//DNA methylation;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA"	--
ENSG00000134684	25.43	25.58	26.215	26.162	22.467	37.999	1294	1297	982	979	966	1396	YARS1	tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01866	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004831//tyrosine-tRNA ligase activity;GO:0005153//interleukin-8 receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006437//tyrosyl-tRNA aminoacylation;GO:0006915//apoptotic process	--
ENSG00000134686	48.292	56.324	56.725	56.596	55.341	56.512	2560	2755	2121	2242	2428	2124	PHC2	polyhomeotic homolog 2 [Source:HGNC Symbol;Acc:HGNC:3183]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0007283//spermatogenesis;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000134690	0.698	0.364	0.539	0.467	0.466	0.727	34	18	19	17	19	26	CDCA8	cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010369//chromocenter;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0032133//chromosome passenger complex;GO:0032991//protein-containing complex;GO:0045171//intercellular bridge;GO:0051233//spindle midzone"	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007080//mitotic metaphase plate congression;GO:0051256//mitotic spindle midzone assembly;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1901970//positive regulation of mitotic sister chromatid separation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1903490//positive regulation of mitotic cytokinesis	--
ENSG00000134697	6.873	5.919	4.028	3.13	3.035	4.568	335	290	145	113	125	162	GNL2	G protein nucleolar 2 [Source:HGNC Symbol;Acc:HGNC:29925]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14537	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043232//intracellular non-membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0008150//biological_process;GO:0042254//ribosome biogenesis	--
ENSG00000134698	2.599	2.269	2.217	1.817	2.323	2.433	392	344	247	203	296.08	267	AGO4	argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K11593	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070578//RISC-loading complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding	GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0007130//synaptonemal complex assembly;GO:0007140//male meiotic nuclear division;GO:0008584//male gonad development;GO:0010501//RNA secondary structure unwinding;GO:0010586//miRNA metabolic process;GO:0016246//RNA interference;GO:0022604//regulation of cell morphogenesis;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0043066//negative regulation of apoptotic process	--
ENSG00000134709	6.174	4.803	4.683	4.01	3.907	4.381	689	563	408	352	384	370	HOOK1	hook microtubule tethering protein 1 [Source:HGNC Symbol;Acc:HGNC:19884]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030897//HOPS complex;GO:0070695//FHF complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051959//dynein light intermediate chain binding	GO:0007030//Golgi organization;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization;GO:0045022//early endosome to late endosome transport;GO:1905198//manchette assembly;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000134716	0.872	0.74	0.721	0.658	0.577	0.705	34	29	20	19	19	20	CYP2J2	cytochrome P450 family 2 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:2634]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Cardiovascular disease;Nervous system;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko04726//Serotonergic synapse;ko04750//Inflammatory mediator regulation of TRP channels;ko00590//Arachidonic acid metabolism;ko04913//Ovarian steroidogenesis;ko00591//Linoleic acid metabolism	K07418;K07418;K07418;K07418;K07418;K07418;K07418	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0008404//arachidonic acid 14,15-epoxygenase activity;GO:0008405//arachidonic acid 11,12-epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0071614//linoleic acid epoxygenase activity;GO:0106255//hydroperoxy icosatetraenoate isomerase activity;GO:0106301//arachidonic acid 5,6-epoxygenase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008016//regulation of heart contraction;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0043651//linoleic acid metabolic process	--
ENSG00000134717	41.382	42.625	37.026	34.702	37.704	38.069	1799	1761	1234	1033	1315	1087	BTF3L4	basic transcription factor 3 like 4 [Source:HGNC Symbol;Acc:HGNC:30547]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000134744	10.378	10.065	8.937	6.495	9.896	7.51	819	675	479	370	534	472	TUT4	terminal uridylyl transferase 4 [Source:HGNC Symbol;Acc:HGNC:28981]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0050265//RNA uridylyltransferase activity	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001556//oocyte maturation;GO:0010526//negative regulation of transposition, RNA-mediated;GO:0010586//miRNA metabolic process;GO:0010587//miRNA catabolic process;GO:0019827//stem cell population maintenance;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0031123//RNA 3'-end processing;GO:0071076//RNA 3' uridylation;GO:1990074//polyuridylation-dependent mRNA catabolic process"	--
ENSG00000134748	8.937	7.846	7.198	6.007	6.75	6.572	970	856	577	483	619	519	PRPF38A	pre-mRNA processing factor 38A [Source:HGNC Symbol;Acc:HGNC:25930]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12849	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000134755	8.043	8.304	6.969	6.43	6.456	7.245	889	898	557	523	610	579	DSC2	desmocollin 2 [Source:HGNC Symbol;Acc:HGNC:3036]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K07601	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009267//cellular response to starvation;GO:0048731//system development;GO:0086042//cardiac muscle cell-cardiac muscle cell adhesion;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential	--
ENSG00000134757	0	0	0	0	0	0	0	0	0	0	0	0	DSG3	desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050]	-	-	-	-	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0098609//cell-cell adhesion	--
ENSG00000134758	7.707	10.545	7.404	8.394	9.068	7.498	403	376	278	268	317	294	RNF138	ring finger protein 138 [Source:HGNC Symbol;Acc:HGNC:17765]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0035861//site of double-strand break	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination	--
ENSG00000134759	18.021	19.408	19.301	14.634	16.795	16.911	1615	1490	1205	958	1144	1127.76	ELP2	elongator acetyltransferase complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:18248]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0033588//elongator holoenzyme complex	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0002098//tRNA wobble uridine modification;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006417//regulation of translation;GO:0008033//tRNA processing;GO:0046425//regulation of receptor signaling pathway via JAK-STAT	--
ENSG00000134760	0	0	0	0.018	0.024	0	0	0	0	2	3	0	DSG1	desmoglein 1 [Source:HGNC Symbol;Acc:HGNC:3048]	Human Diseases	Infectious disease: bacterial	ko05150//Staphylococcus aureus infection	K07596	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0101003//ficolin-1-rich granule membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015643//toxic substance binding;GO:0045295//gamma-catenin binding;GO:0046872//metal ion binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0032570//response to progesterone;GO:0050821//protein stabilization;GO:0060135//maternal process involved in female pregnancy;GO:0098609//cell-cell adhesion	--
ENSG00000134762	2.336	1.898	1.211	2.058	1.546	1.712	346	280	134	185	189	188	DSC3	desmocollin 3 [Source:HGNC Symbol;Acc:HGNC:3037]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome	GO:0005509//calcium ion binding;GO:0045295//gamma-catenin binding;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050821//protein stabilization;GO:0098609//cell-cell adhesion	--
ENSG00000134765	0.832	0.555	0.539	0.569	0.58	0.764	73	49	35	37	43	49	DSC1	desmocollin 1 [Source:HGNC Symbol;Acc:HGNC:3035]	-	-	-	-	GO:0001533//cornified envelope;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005921//gap junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0110165//cellular anatomical entity	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0098609//cell-cell adhesion	--
ENSG00000134769	32.496	31.456	31.294	26.282	29.286	31.675	2554	2435	1671	1560	1949	1858	DTNA	dystrobrevin alpha [Source:HGNC Symbol;Acc:HGNC:3057]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0045111//intermediate filament cytoskeleton;GO:0045202//synapse	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006941//striated muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0099536//synaptic signaling	--
ENSG00000134775	10.147	10.008	12.242	10.232	10.277	9.4	859.33	883.89	713.66	661.42	696.81	555.74	FHOD3	formin homology 2 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26178]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030018//Z disc	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0030837//negative regulation of actin filament polymerization;GO:0030866//cortical actin cytoskeleton organization;GO:0045214//sarcomere organization;GO:0051639//actin filament network formation;GO:0055003//cardiac myofibril assembly	--
ENSG00000134779	160.416	144.725	147.153	131.633	122.129	128.432	5064.67	5014.11	3566.34	3019.58	3536.19	2770.26	TPGS2	tubulin polyglutamylase complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24561]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding	GO:0018095//protein polyglutamylation	--
ENSG00000134780	2.087	2.299	2.51	2.626	2.873	2.891	251	278	223	234	292	253	DAGLA	diacylglycerol lipase alpha [Source:HGNC Symbol;Acc:HGNC:1165]	Organismal Systems;Organismal Systems	Nervous system;Endocrine system	ko04723//Retrograde endocannabinoid signaling;ko04925//Aldosterone synthesis and secretion	K13806;K13806	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031901//early endosome membrane;GO:0032590//dendrite membrane;GO:0032591//dendritic spine membrane;GO:0042995//cell projection;GO:0043196//varicosity;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0099055//integral component of postsynaptic membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047372//acylglycerol lipase activity	GO:0006629//lipid metabolic process;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007405//neuroblast proliferation;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0022008//neurogenesis;GO:0042136//neurotransmitter biosynthetic process;GO:0046340//diacylglycerol catabolic process;GO:0071926//endocannabinoid signaling pathway;GO:0098921//retrograde trans-synaptic signaling by endocannabinoid;GO:0150077//regulation of neuroinflammatory response	--
ENSG00000134802	2.654	1.606	1.806	1.284	1.923	1.713	74	82	67	48	80	54	SLC43A3	solute carrier family 43 member 3 [Source:HGNC Symbol;Acc:HGNC:17466]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0015207//adenine transmembrane transporter activity;GO:0015208//guanine transmembrane transporter activity;GO:0015245//fatty acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0008150//biological_process;GO:0015853//adenine transport;GO:0015908//fatty acid transport;GO:0035344//hypoxanthine transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:1903716//guanine transmembrane transport	--
ENSG00000134809	15.439	15.976	15.654	19.303	15.779	17.986	211	221	158	197	178	175	TIMM10	translocase of inner mitochondrial membrane 10 [Source:HGNC Symbol;Acc:HGNC:11814]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0032977//membrane insertase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000134812	0	0	0	0	0	0	0	0	0	0	0	0	CBLIF	cobalamin binding intrinsic factor [Source:HGNC Symbol;Acc:HGNC:4268]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14615	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005902//microvillus;GO:0016324//apical plasma membrane;GO:0043202//lysosomal lumen	GO:0005515//protein binding;GO:0031419//cobalamin binding	GO:0006811//ion transport;GO:0006824//cobalt ion transport;GO:0009235//cobalamin metabolic process;GO:0015889//cobalamin transport	--
ENSG00000134815	3.881	4.196	4.285	5.445	4.981	4.79	297	338	261	276	328	272	DHX34	DExH-box helicase 34 [Source:HGNC Symbol;Acc:HGNC:16719]	-	-	-	-	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0044877//protein-containing complex binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042327//positive regulation of phosphorylation;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000134817	0	0	0	0	0.016	0	0	0	0	0	1	0	APLNR	apelin receptor [Source:HGNC Symbol;Acc:HGNC:339]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04371//Apelin signaling pathway	K04174;K04174	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0060182//apelin receptor activity	GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0003171//atrioventricular valve development;GO:0003272//endocardial cushion formation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007369//gastrulation;GO:0007507//heart development;GO:0007512//adult heart development;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0031065//positive regulation of histone deacetylation;GO:0035886//vascular associated smooth muscle cell differentiation;GO:0035904//aorta development;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0045766//positive regulation of angiogenesis;GO:0050878//regulation of body fluid levels;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060183//apelin receptor signaling pathway;GO:0060412//ventricular septum morphogenesis;GO:0060841//venous blood vessel development;GO:0060976//coronary vasculature development;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903596//regulation of gap junction assembly;GO:1904325//positive regulation of inhibitory G protein-coupled receptor phosphorylation	--
ENSG00000134824	305.747	322.091	328.745	356.887	357.482	359.513	18440.24	19266.95	14733	16018	18204	15697	FADS2	fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575]	Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids;ko00592//alpha-Linolenic acid metabolism	K10226;K10226;K10226;K10226;K10226	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0005515//protein binding;GO:0016213//linoleoyl-CoA desaturase activity;GO:0016491//oxidoreductase activity;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0043651//linoleic acid metabolic process	--
ENSG00000134825	12.48	12.939	15.465	14.59	11.347	11.106	154	159	137	132	116	100	TMEM258	transmembrane protein 258 [Source:HGNC Symbol;Acc:HGNC:1164]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0034998//oligosaccharyltransferase I complex;GO:0043227//membrane-bounded organelle	GO:0005515//protein binding	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation	--
ENSG00000134827	0.065	0.032	0.088	0.175	0.269	0.268	2	1	2	4	7	6	TCN1	transcobalamin 1 [Source:HGNC Symbol;Acc:HGNC:11652]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14615	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	GO:0005515//protein binding;GO:0031419//cobalamin binding	GO:0006811//ion transport;GO:0006824//cobalt ion transport;GO:0015889//cobalamin transport	--
ENSG00000134830	0	0	0.101	0.01	0	0.125	0	0	2	1	0	5	C5AR2	complement C5a receptor 2 [Source:HGNC Symbol;Acc:HGNC:4527]	-	-	-	-	GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell	GO:0004875//complement receptor activity;GO:0004878//complement component C5a receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0002430//complement receptor mediated signaling pathway;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032677//regulation of interleukin-8 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0038178//complement component C5a signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090024//negative regulation of neutrophil chemotaxis	--
ENSG00000134851	35.622	31.759	31.083	30.121	31.417	36.794	1415	1263	909	885	1050	1059	TMEM165	transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005384//manganese ion transmembrane transporter activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0006487//protein N-linked glycosylation;GO:0006874//cellular calcium ion homeostasis;GO:0032468//Golgi calcium ion homeostasis;GO:0032472//Golgi calcium ion transport;GO:0035751//regulation of lysosomal lumen pH;GO:0070588//calcium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport	--
ENSG00000134852	6.201	3.835	3.797	3.101	3.637	4.512	1136	751	544	463	595	645	CLOCK	clock circadian regulator [Source:HGNC Symbol;Acc:HGNC:2082]	Organismal Systems;Organismal Systems	Nervous system;Environmental adaptation	ko04728//Dopaminergic synapse;ko04710//Circadian rhythm	K02223;K02223	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0033391//chromatoid body;GO:0043231//intracellular membrane-bounded organelle;GO:1990513//CLOCK-BMAL transcription complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000077//DNA damage checkpoint signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006473//protein acetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0009648//photoperiodism;GO:0016573//histone acetylation;GO:0032922//circadian regulation of gene expression;GO:0042634//regulation of hair cycle;GO:0042752//regulation of circadian rhythm;GO:0042753//positive regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0050729//positive regulation of inflammatory response;GO:0050796//regulation of insulin secretion;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051775//response to redox state;GO:0071479//cellular response to ionizing radiation;GO:2000074//regulation of type B pancreatic cell development;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway"	bHLH
ENSG00000134853	2.572	2.044	2.242	1.765	1.913	1.923	252.29	263	219.02	173	197	185.12	PDGFRA	platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Transport and catabolism;Signal transduction;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko05230//Central carbon metabolism in cancer	K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005929//cilium;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031226//intrinsic component of plasma membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005018//platelet-derived growth factor alpha-receptor activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0038085//vascular endothelial growth factor binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0048407//platelet-derived growth factor binding	GO:0001553//luteinization;GO:0001701//in utero embryonic development;GO:0001775//cell activation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008210//estrogen metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008585//female gonad development;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010544//negative regulation of platelet activation;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030198//extracellular matrix organization;GO:0030324//lung development;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0030539//male genitalia development;GO:0033327//Leydig cell differentiation;GO:0033674//positive regulation of kinase activity;GO:0034614//cellular response to reactive oxygen species;GO:0035790//platelet-derived growth factor receptor-alpha signaling pathway;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0046777//protein autophosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0048557//embryonic digestive tract morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0050872//white fat cell differentiation;GO:0050920//regulation of chemotaxis;GO:0055003//cardiac myofibril assembly;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0060326//cell chemotaxis;GO:0061298//retina vasculature development in camera-type eye;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0071230//cellular response to amino acid stimulus;GO:0072277//metanephric glomerular capillary formation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000739//regulation of mesenchymal stem cell differentiation	--
ENSG00000134864	1.026	1.233	1.861	0.968	2.389	1.122	56.28	43.12	33.1	40	43	23	GGACT	gamma-glutamylamine cyclotransferase [Source:HGNC Symbol;Acc:HGNC:25100]	-	-	-	-	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016829//lyase activity;GO:0061929//gamma-glutamylaminecyclotransferase activity	GO:0042219//cellular modified amino acid catabolic process	--
ENSG00000134871	100.872	111.284	71.667	84.998	101.63	76.724	13344	14742	6961	8208	11130	7202	COL4A2	collagen type IV alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2203]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	"GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0007568//aging;GO:0014823//response to activity;GO:0016525//negative regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0035987//endodermal cell differentiation;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus"	--
ENSG00000134873	4.198	4.323	3.489	4.088	2.922	3.764	206.48	222.24	127.74	154.87	122.08	136.03	CLDN10	claudin 10 [Source:HGNC Symbol;Acc:HGNC:2033]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0043269//regulation of ion transport;GO:0070830//bicellular tight junction assembly	--
ENSG00000134874	13.415	11.462	12.054	9.362	9.195	8.855	1948.52	1706.76	1138.26	914.13	1185.92	1000.97	DZIP1	DAZ interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:20908]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016607//nuclear speck;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097539//ciliary transition fiber;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0060090//molecular adaptor activity;GO:0062063//BBSome binding	GO:0007224//smoothened signaling pathway;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0007507//heart development;GO:0030154//cell differentiation;GO:0032053//ciliary basal body organization;GO:0033365//protein localization to organelle;GO:0043393//regulation of protein binding;GO:0044782//cilium organization;GO:0045184//establishment of protein localization;GO:0045724//positive regulation of cilium assembly;GO:0051220//cytoplasmic sequestering of protein;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0120316//sperm flagellum assembly;GO:0140706//protein-containing complex localization to centriolar satellite;GO:1903566//positive regulation of protein localization to cilium	--
ENSG00000134882	30.34	31.351	29.978	31.089	28.472	31.8	1404	1475	1031	1078	1109	1074	UBAC2	UBA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20486]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	"GO:0016055//Wnt signaling pathway;GO:0070972//protein localization to endoplasmic reticulum;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000134884	6.121	6.076	5.726	5.245	6.312	6.738	427	426	295	271	372	342	ARGLU1	arginine and glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:25482]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0045296//cadherin binding	-	--
ENSG00000134897	15.135	13.585	12.649	12.4	11.818	14.919	902.89	847.62	615	570	626.46	670	BIVM	"basic, immunoglobulin-like variable motif containing [Source:HGNC Symbol;Acc:HGNC:16034]"	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000134899	8.306	6.67	6.378	5.085	5.425	5.633	676.71	547.19	384	309	373.88	334	ERCC5	"ERCC excision repair 5, endonuclease [Source:HGNC Symbol;Acc:HGNC:3437]"	Genetic Information Processing	Replication and repair	ko03420//Nucleotide excision repair	K10846	GO:0000109//nucleotide-excision repair complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005694//chromosome;GO:0032991//protein-containing complex	"GO:0000405//bubble DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding"	"GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006285//base-excision repair, AP site formation;GO:0006289//nucleotide-excision repair;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006807//nitrogen compound metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0009650//UV protection;GO:0010225//response to UV-C;GO:0043066//negative regulation of apoptotic process;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0050790//regulation of catalytic activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000134900	10.881	10.119	10.933	7.075	7.418	8.568	857	733	474	351	526	468	TPP2	tripeptidyl peptidase 2 [Source:HGNC Symbol;Acc:HGNC:12016]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0000209//protein polyubiquitination;GO:0006508//proteolysis;GO:0080144//amino acid homeostasis	--
ENSG00000134901	18.058	16.335	16.279	12.254	14.034	16.034	760	691	506	382	499	491	POGLUT2	protein O-glucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:19350]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0012505//endomembrane system	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity;GO:0035252//UDP-xylosyltransferase activity;GO:0046527//glucosyltransferase activity;GO:0140561//EGF-domain serine glucosyltransferase activity;GO:0140562//EGF-domain serine xylosyltransferase activity	GO:0006486//protein glycosylation;GO:0018242//protein O-linked glycosylation via serine	--
ENSG00000134905	21.666	23.652	25.334	26.78	22.931	26.641	795	863	677	710	705	685	CARS2	"cysteinyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25695]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01883	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004817//cysteine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006423//cysteinyl-tRNA aminoacylation	--
ENSG00000134909	5.256	5.808	4.529	4.233	4.942	4.868	905	862	603	544	697	671	ARHGAP32	Rho GTPase activating protein 32 [Source:HGNC Symbol;Acc:HGNC:17399]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000134910	70.143	73.452	82.178	74.813	74.765	83.981	3855	4089	3317	2982	3419	3290	STT3A	STT3 oligosaccharyltransferase complex catalytic subunit A [Source:HGNC Symbol;Acc:HGNC:6172]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K07151;K07151;K07151;K07151	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035000//oligosaccharyltransferase III complex	GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043686//co-translational protein modification;GO:0043687//post-translational protein modification	--
ENSG00000134917	0.651	0.701	0.396	0.825	0.928	0.53	49	53	22	46	59	29	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif 8 [Source:HGNC Symbol;Acc:HGNC:224]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0009673//low-affinity phosphate transmembrane transporter activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008285//negative regulation of cell population proliferation;GO:0030198//extracellular matrix organization;GO:0035435//phosphate ion transmembrane transport	--
ENSG00000134940	0	0	0	0	0	0	0	0	0	0	0	0	ACRV1	acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0007275//multicellular organism development	--
ENSG00000134954	14.583	12.683	14.278	12.034	12.6	13.457	1291	1068	864	761	877	860	ETS1	"ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]"	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04218//Cellular senescence;ko05211//Renal cell carcinoma	K02678;K02678;K02678;K02678;K02678	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006955//immune response;GO:0008285//negative regulation of cell population proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030578//PML body organization;GO:0042981//regulation of apoptotic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045765//regulation of angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046677//response to antibiotic;GO:0048870//cell motility;GO:0050729//positive regulation of inflammatory response;GO:0051272//positive regulation of cellular component movement;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell"	ETS
ENSG00000134955	0.171	0.049	0.05	0.074	0.029	0.034	14	4	3	4	2	2	SLC37A2	solute carrier family 37 member 2 [Source:HGNC Symbol;Acc:HGNC:20644]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0015297//antiporter activity;GO:0022857//transmembrane transporter activity;GO:0061513//glucose 6-phosphate:inorganic phosphate antiporter activity	GO:0008643//carbohydrate transport;GO:0015760//glucose-6-phosphate transport;GO:0035435//phosphate ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000134962	0.04	0	0.022	0.011	0.057	0	5	0	2	1	6	0	KLB	klotho beta [Source:HGNC Symbol;Acc:HGNC:15527]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K22404	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding"	GO:0005975//carbohydrate metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	--
ENSG00000134970	40.728	34.688	36.246	32.012	30.028	36.602	3309.86	2833.5	2175.49	1927.03	2061.66	2164.27	TMED7	transmembrane p24 trafficking protein 7 [Source:HGNC Symbol;Acc:HGNC:24253]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030126//COPI vesicle coat;GO:0030127//COPII vesicle coat;GO:0030133//transport vesicle;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	-	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport	--
ENSG00000134982	84.098	49.78	51.102	34.934	46.007	47.368	16462.91	9855.99	6821	4862.97	7230	6507.99	APC	APC regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:583]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cell motility;Cancer: overview;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05210//Colorectal cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer	K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0016342//catenin complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030877//beta-catenin destruction complex;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:1990909//Wnt signalosome	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008017//microtubule binding;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0045295//gamma-catenin binding;GO:0051010//microtubule plus-end binding;GO:0070840//dynein complex binding	GO:0000281//mitotic cytokinesis;GO:0001708//cell fate specification;GO:0006974//cellular response to DNA damage stimulus;GO:0007026//negative regulation of microtubule depolymerization;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007155//cell adhesion;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0010942//positive regulation of cell death;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030335//positive regulation of cell migration;GO:0031274//positive regulation of pseudopodium assembly;GO:0032886//regulation of microtubule-based process;GO:0043065//positive regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045595//regulation of cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0051726//regulation of cell cycle;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0065003//protein-containing complex assembly;GO:0070830//bicellular tight junction assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:1904781//positive regulation of protein localization to centrosome;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000134986	125.272	133.138	131.362	137.563	134.875	118.629	4835	5187	3816	3983	4506	3360	NREP	neuronal regeneration related protein [Source:HGNC Symbol;Acc:HGNC:16834]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0031103//axon regeneration;GO:0045664//regulation of neuron differentiation	--
ENSG00000134987	5.343	4.65	4.517	3.307	4.002	4.327	711	622	444	326	450	419	WDR36	WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14554	GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0005515//protein binding	GO:0001895//retina homeostasis;GO:0006364//rRNA processing;GO:0030516//regulation of axon extension	--
ENSG00000134996	6.867	6.049	7.361	6.663	6.773	6.734	192	170	152	138	160	137	OSTF1	osteoclast stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:8510]	-	-	-	-	GO:0005576//extracellular region;GO:0005622//intracellular anatomical structure;GO:0005737//cytoplasm;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0001503//ossification;GO:0007165//signal transduction	--
ENSG00000135002	21.487	16.74	16.344	18.754	15.123	16.795	1157	906	650	748	688	658	RFK	riboflavin kinase [Source:HGNC Symbol;Acc:HGNC:30324]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00740//Riboflavin metabolism	K00861;K00861	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008531//riboflavin kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006771//riboflavin metabolic process;GO:0006915//apoptotic process;GO:0009231//riboflavin biosynthetic process;GO:0009398//FMN biosynthetic process;GO:0016310//phosphorylation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0072593//reactive oxygen species metabolic process	--
ENSG00000135018	34.973	34.14	33.562	27.943	29.67	32.342	2467	2338	1674	1494	1650	1618	UBQLN1	ubiquilin 1 [Source:HGNC Symbol;Acc:HGNC:12508]	Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Folding, sorting and degradation"	ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum	K04523;K04523	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016235//aggresome;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding	GO:0000045//autophagosome assembly;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0016236//macroautophagy;GO:0016241//regulation of macroautophagy;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031396//regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0034140//negative regulation of toll-like receptor 3 signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0035973//aggrephagy;GO:0071456//cellular response to hypoxia;GO:0097352//autophagosome maturation;GO:1901340//negative regulation of store-operated calcium channel activity;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process	--
ENSG00000135040	6.308	5.402	5.062	5.102	5.114	5.202	659	612	415	381	469	425	NAA35	"N-alpha-acetyltransferase 35, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:24340]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005886//plasma membrane;GO:0031417//NatC complex	GO:0005515//protein binding	GO:0006474//N-terminal protein amino acid acetylation;GO:0017196//N-terminal peptidyl-methionine acetylation;GO:0043066//negative regulation of apoptotic process;GO:0048659//smooth muscle cell proliferation	--
ENSG00000135045	2.789	2.285	2.221	1.855	2.549	2.198	136	112	80	67	105	78	C9orf40	chromosome 9 open reading frame 40 [Source:HGNC Symbol;Acc:HGNC:23433]	-	-	-	-	-	-	-	--
ENSG00000135046	54.322	54.418	45.418	35.58	34.654	36.086	1579	1585	976	761	852	763	ANXA1	annexin A1 [Source:HGNC Symbol;Acc:HGNC:533]	-	-	-	-	GO:0001533//cornified envelope;GO:0001891//phagocytic cup;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0019898//extrinsic component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031313//extrinsic component of endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043227//membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004859//phospholipase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019834//phospholipase A2 inhibitor activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion	"GO:0001780//neutrophil homeostasis;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002548//monocyte chemotaxis;GO:0002685//regulation of leukocyte migration;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008360//regulation of cell shape;GO:0010165//response to X-ray;GO:0014839//myoblast migration involved in skeletal muscle regeneration;GO:0018149//peptide cross-linking;GO:0030073//insulin secretion;GO:0030216//keratinocyte differentiation;GO:0030850//prostate gland development;GO:0031018//endocrine pancreas development;GO:0031340//positive regulation of vesicle fusion;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0031532//actin cytoskeleton reorganization;GO:0032355//response to estradiol;GO:0032508//DNA duplex unwinding;GO:0032652//regulation of interleukin-1 production;GO:0032717//negative regulation of interleukin-8 production;GO:0032743//positive regulation of interleukin-2 production;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042063//gliogenesis;GO:0042102//positive regulation of T cell proliferation;GO:0042119//neutrophil activation;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043434//response to peptide hormone;GO:0045087//innate immune response;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0045920//negative regulation of exocytosis;GO:0046632//alpha-beta T cell differentiation;GO:0046883//regulation of hormone secretion;GO:0050482//arachidonic acid secretion;GO:0050727//regulation of inflammatory response;GO:0070301//cellular response to hydrogen peroxide;GO:0070365//hepatocyte differentiation;GO:0070459//prolactin secretion;GO:0070555//response to interleukin-1;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071621//granulocyte chemotaxis;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090303//positive regulation of wound healing;GO:0097350//neutrophil clearance;GO:0098609//cell-cell adhesion;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1900138//negative regulation of phospholipase A2 activity"	--
ENSG00000135047	62.928	67.29	69.356	70.497	67.941	74.933	2156	2345	1767	1754	1952	1893	CTSL	cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]	Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems	Transport and catabolism;Cancer: overview;Immune disease;Transport and catabolism;Cell growth and death;Cardiovascular disease;Transport and catabolism;Immune system	ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko05323//Rheumatoid arthritis;ko04140//Autophagy - animal;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04142//Lysosome;ko04612//Antigen processing and presentation	K01365;K01365;K01365;K01365;K01365;K01365;K01365;K01365	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005771//multivesicular body;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0036021//endolysosome lumen;GO:0042583//chromaffin granule;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen	GO:0001968//fibronectin binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0043394//proteoglycan binding;GO:0097655//serpin family protein binding	"GO:0002250//adaptive immune response;GO:0006508//proteolysis;GO:0006955//immune response;GO:0016540//protein autoprocessing;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030574//collagen catabolic process;GO:0031638//zymogen activation;GO:0034230//enkephalin processing;GO:0039654//fusion of virus membrane with host endosome membrane;GO:0043373//CD4-positive, alpha-beta T cell lineage commitment;GO:0046718//viral entry into host cell;GO:0048002//antigen processing and presentation of peptide antigen;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0060309//elastin catabolic process;GO:0071888//macrophage apoptotic process;GO:0097067//cellular response to thyroid hormone stimulus"	--
ENSG00000135048	21.621	23.332	24.84	18.636	20.252	20.676	2441	2567	1870	1487	1927	1790	CEMIP2	cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869]	-	-	-	-	GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004415//hyalurononglucosaminidase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0045296//cadherin binding"	GO:0001525//angiogenesis;GO:0008152//metabolic process;GO:0030214//hyaluronan catabolic process;GO:1903670//regulation of sprouting angiogenesis	--
ENSG00000135049	5.477	4.58	4.365	3.596	4.482	4.223	503	423	297	246	348	284	AGTPBP1	ATP/GTP binding carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:17258]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:1904115//axon cytoplasm	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001754//eye photoreceptor cell differentiation;GO:0006508//proteolysis;GO:0007005//mitochondrion organization;GO:0007628//adult walking behavior;GO:0008285//negative regulation of cell population proliferation;GO:0021549//cerebellum development;GO:0021680//cerebellar Purkinje cell layer development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021772//olfactory bulb development;GO:0021954//central nervous system neuron development;GO:0035608//protein deglutamylation;GO:0035609//C-terminal protein deglutamylation;GO:0035610//protein side chain deglutamylation;GO:0042133//neurotransmitter metabolic process;GO:0050905//neuromuscular process;GO:0060041//retina development in camera-type eye;GO:0098930//axonal transport;GO:0098957//anterograde axonal transport of mitochondrion;GO:0098958//retrograde axonal transport of mitochondrion;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000135052	48.96	44.727	44.04	42.376	43.759	43.396	3044	2840	2029	1982	2335	1994	GOLM1	golgi membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:15451]	-	-	-	-	GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006997//nucleus organization;GO:0019216//regulation of lipid metabolic process	--
ENSG00000135063	8.331	9.469	10.128	8.49	8.524	8.376	399	454	368	309	359	301	FAM189A2	family with sequence similarity 189 member A2 [Source:HGNC Symbol;Acc:HGNC:24820]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000135069	68.82	63.922	71.98	81.279	77.304	118.412	3149	2935	2429	2736	2979	3930	PSAT1	phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:19129]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism;ko00750//Vitamin B6 metabolism"	K00831;K00831;K00831;K00831;K00831;K00831	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004648//O-phospho-L-serine:2-oxoglutarate aminotransferase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006564//L-serine biosynthetic process;GO:0008615//pyridoxine biosynthetic process;GO:0008652//cellular amino acid biosynthetic process	--
ENSG00000135070	28.491	27.749	29.277	30.42	29.376	31.176	1157	1132	876	902	992	905	ISCA1	iron-sulfur cluster assembly 1 [Source:HGNC Symbol;Acc:HGNC:28660]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000135074	4.248	4.344	2.991	1.617	2.263	1.37	559	565	297	161	257	134	ADAM19	ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]	-	-	-	-	GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding;GO:1902945//metalloendopeptidase activity involved in amyloid precursor protein catabolic process	GO:0001890//placenta development;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0010628//positive regulation of gene expression;GO:0016485//protein processing;GO:0042987//amyloid precursor protein catabolic process;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin	--
ENSG00000135077	0	0	0	0	0	0	0	0	0	0	0	0	HAVCR2	hepatitis A virus cellular receptor 2 [Source:HGNC Symbol;Acc:HGNC:18437]	-	-	-	-	GO:0001772//immunological synapse;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001819//positive regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0002519//natural killer cell tolerance induction;GO:0002652//regulation of tolerance induction dependent upon immune response;GO:0002826//negative regulation of T-helper 1 type immune response;GO:0002838//negative regulation of immune response to tumor cell;GO:0002859//negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0006954//inflammatory response;GO:0010629//negative regulation of gene expression;GO:0030886//negative regulation of myeloid dendritic cell activation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032480//negative regulation of type I interferon production;GO:0032687//negative regulation of interferon-alpha production;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0032712//negative regulation of interleukin-3 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032722//positive regulation of chemokine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032732//positive regulation of interleukin-1 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032815//negative regulation of natural killer cell activation;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0043032//positive regulation of macrophage activation;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045824//negative regulation of innate immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0060135//maternal process involved in female pregnancy;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071656//negative regulation of granulocyte colony-stimulating factor production;GO:1900425//negative regulation of defense response to bacterium;GO:1900426//positive regulation of defense response to bacterium;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000521//negative regulation of immunological synapse formation;GO:2001189//negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	--
ENSG00000135083	2.529	2.087	1.59	1.929	2.282	1.694	139	94	61	70	103	87	CCNJL	cyclin J like [Source:HGNC Symbol;Acc:HGNC:25876]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0044772//mitotic cell cycle phase transition	--
ENSG00000135090	9.34	8.89	7.851	7.025	7.575	7.741	522	532	348	299	334	324	TAOK3	TAO kinase 3 [Source:HGNC Symbol;Acc:HGNC:18133]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04429	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0016310//phosphorylation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043408//regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0046329//negative regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048812//neuron projection morphogenesis	--
ENSG00000135093	12.483	15.283	12.607	12.746	12.383	12.78	801	936	675	646	786	699	USP30	ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K11851	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0101005//deubiquitinase activity	GO:0000422//autophagy of mitochondrion;GO:0000425//pexophagy;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008053//mitochondrial fusion;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0044313//protein K6-linked deubiquitination;GO:1901525//negative regulation of mitophagy	--
ENSG00000135094	0	0	0	0	0	0	0	0	0	0	0	0	SDS	serine dehydratase [Source:HGNC Symbol;Acc:HGNC:10691]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism;ko00290//Valine, leucine and isoleucine biosynthesis"	K17989;K17989;K17989;K17989;K17989;K17989	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003941//L-serine ammonia-lyase activity;GO:0004794//L-threonine ammonia-lyase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity	GO:0006094//gluconeogenesis;GO:0006520//cellular amino acid metabolic process;GO:0006565//L-serine catabolic process;GO:0006567//threonine catabolic process;GO:0006629//lipid metabolic process;GO:0009097//isoleucine biosynthetic process;GO:0042866//pyruvate biosynthetic process	--
ENSG00000135097	8.643	9.734	13.39	12.333	12.782	13.54	425	463	440	391	434	461	MSI1	musashi RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7330]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14411	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005844//polysome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:0009725//response to hormone;GO:0030855//epithelial cell differentiation	--
ENSG00000135100	0	0	0	0	0	0	0	0	0	0	0	0	HNF1A	HNF1 homeobox A [Source:HGNC Symbol;Acc:HGNC:11621]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08036	GO:0000785//chromatin;GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0045120//pronucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001824//blastocyst development;GO:0001889//liver development;GO:0001890//placenta development;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006633//fatty acid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0006783//heme biosynthetic process;GO:0006979//response to oxidative stress;GO:0008104//protein localization;GO:0008203//cholesterol metabolic process;GO:0009749//response to glucose;GO:0015721//bile acid and bile salt transport;GO:0015908//fatty acid transport;GO:0016573//histone acetylation;GO:0030073//insulin secretion;GO:0030111//regulation of Wnt signaling pathway;GO:0030326//embryonic limb morphogenesis;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0035623//renal glucose absorption;GO:0042593//glucose homeostasis;GO:0043691//reverse cholesterol transport;GO:0045453//bone resorption;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046323//glucose import;GO:0046883//regulation of hormone secretion;GO:0048341//paraxial mesoderm formation;GO:0048608//reproductive structure development;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060395//SMAD protein signal transduction"	Homeobox
ENSG00000135108	19.006	18.095	18.426	15.348	16.013	17.552	1761	1713	1269	1036	1261	1211	FBXO21	F-box protein 21 [Source:HGNC Symbol;Acc:HGNC:13592]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000135111	1.067	0.821	0.662	0.413	0.615	0.671	103	81	48	30	51	46	TBX3	T-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11602]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K10177	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0001947//heart looping;GO:0003007//heart morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003167//atrioventricular bundle cell differentiation;GO:0003205//cardiac chamber development;GO:0003272//endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007569//cell aging;GO:0008284//positive regulation of cell population proliferation;GO:0008595//anterior/posterior axis specification, embryo;GO:0009887//animal organ morphogenesis;GO:0010159//specification of animal organ position;GO:0019827//stem cell population maintenance;GO:0021761//limbic system development;GO:0030539//male genitalia development;GO:0030540//female genitalia development;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030879//mammary gland development;GO:0032275//luteinizing hormone secretion;GO:0035050//embryonic heart tube development;GO:0035108//limb morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0036302//atrioventricular canal development;GO:0042127//regulation of cell population proliferation;GO:0042472//inner ear morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0045662//negative regulation of myoblast differentiation;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046884//follicle-stimulating hormone secretion;GO:0048332//mesoderm morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0051145//smooth muscle cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0060021//roof of mouth development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060412//ventricular septum morphogenesis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060596//mammary placode formation;GO:0060923//cardiac muscle cell fate commitment;GO:0060931//sinoatrial node cell development;GO:0072105//ureteric peristalsis;GO:0090398//cellular senescence;GO:1905072//cardiac jelly development;GO:1905222//atrioventricular canal morphogenesis;GO:2000137//negative regulation of cell proliferation involved in heart morphogenesis;GO:2000648//positive regulation of stem cell proliferation"	T-box
ENSG00000135114	0	0	0	0.073	0.044	0.103	0	0	0	2	1	2	OASL	2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K14608	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity;GO:0046966//thyroid hormone receptor binding	GO:0002376//immune system process;GO:0009615//response to virus;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060700//regulation of ribonuclease activity;GO:0070106//interleukin-27-mediated signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000135116	0.15	0.166	0.09	0.124	0.197	0.08	18	20	8	11	20	7	HRK	"harakiri, BCL2 interacting protein [Source:HGNC Symbol;Acc:HGNC:5185]"	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K02512	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0031334//positive regulation of protein-containing complex assembly;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria	--
ENSG00000135119	0.37	0.65	1.296	0.454	0.952	1.223	44	73	75	29	54	59	RNFT2	"ring finger protein, transmembrane 2 [Source:HGNC Symbol;Acc:HGNC:25905]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:1904294//positive regulation of ERAD pathway	--
ENSG00000135124	6.403	7.674	7.212	6.369	8.087	7.991	234	283	195	171	250	211	P2RX4	purinergic receptor P2X 4 [Source:HGNC Symbol;Acc:HGNC:8535]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K05218;K05218	GO:0005639//integral component of nuclear inner membrane;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005102//signaling receptor binding;GO:0005216//ion channel activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0099604//ligand-gated calcium channel activity	GO:0001894//tissue homeostasis;GO:0002028//regulation of sodium ion transport;GO:0002931//response to ischemia;GO:0006811//ion transport;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0019722//calcium-mediated signaling;GO:0032308//positive regulation of prostaglandin secretion;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0034405//response to fluid shear stress;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0042118//endothelial cell activation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048266//behavioral response to pain;GO:0048678//response to axon injury;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050920//regulation of chemotaxis;GO:0050975//sensory perception of touch;GO:0051897//positive regulation of protein kinase B signaling;GO:0051899//membrane depolarization;GO:0051928//positive regulation of calcium ion transport;GO:0055117//regulation of cardiac muscle contraction;GO:0055119//relaxation of cardiac muscle;GO:0060079//excitatory postsynaptic potential;GO:0070588//calcium ion transmembrane transport;GO:0071294//cellular response to zinc ion;GO:0071318//cellular response to ATP;GO:0097190//apoptotic signaling pathway;GO:0098655//cation transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:1904141//positive regulation of microglial cell migration;GO:2001028//positive regulation of endothelial cell chemotaxis	--
ENSG00000135127	9.136	9.146	12.227	13.97	15.112	14.08	612	624	603	699	872	690	BICDL1	BICD family like cargo adaptor 1 [Source:HGNC Symbol;Acc:HGNC:28095]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0031267//small GTPase binding;GO:0034452//dynactin binding	GO:0007399//nervous system development;GO:0031175//neuron projection development;GO:0047496//vesicle transport along microtubule;GO:0055107//Golgi to secretory granule transport	--
ENSG00000135144	0.126	0.042	0.057	0.019	0.017	0.038	9	3	3	1	1	2	DTX1	deltex E3 ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:3060]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06058	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003713//transcription coactivator activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0007166//cell surface receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0008593//regulation of Notch signaling pathway;GO:0010001//glial cell differentiation;GO:0016567//protein ubiquitination;GO:0045581//negative regulation of T cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000135148	30.981	34.558	37.628	35.387	39.885	39.039	1434	1571	1277	1249	1495	1364	TRAFD1	TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0045824//negative regulation of innate immune response	--
ENSG00000135164	6.714	6.636	7.101	4.815	5.573	9.43	463	426	312	217	298	340	DMTF1	cyclin D binding myb like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:14603]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle"	MYB
ENSG00000135175	0	0	0	0	0	0	0	0	0	0	0	0	OCM2	oncomodulin 2 [Source:HGNC Symbol;Acc:HGNC:34396]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000135185	7.128	6.434	7.338	6.726	5.501	5.344	170	158	120	117	119	100	TMEM243	transmembrane protein 243 [Source:HGNC Symbol;Acc:HGNC:21707]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000135205	0.376	0.676	0.586	0.449	1.008	0.298	26	47	27	23	27	15	CCDC146	coiled-coil domain containing 146 [Source:HGNC Symbol;Acc:HGNC:29296]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000135211	18.361	16.517	18.31	18.628	17.113	19.342	334	302	246	251	263	256	TMEM60	transmembrane protein 60 [Source:HGNC Symbol;Acc:HGNC:21754]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000135218	0.423	0.414	0.795	0.236	1.329	0.271	13	18	11	5	38	12	CD36	CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663]	Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Immune system;Signal transduction;Endocrine and metabolic disease;Signaling molecules and interaction;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Digestive system	ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04640//Hematopoietic cell lineage;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04512//ECM-receptor interaction;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko05144//Malaria;ko04979//Cholesterol metabolism;ko04975//Fat digestion and absorption	K06259;K06259;K06259;K06259;K06259;K06259;K06259;K06259;K06259;K06259;K06259;K06259	GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031092//platelet alpha granule membrane;GO:0031526//brush border membrane;GO:0035579//specific granule membrane;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0045177//apical part of cell;GO:0045335//phagocytic vesicle;GO:0071944//cell periphery	GO:0001540//amyloid-beta binding;GO:0005041//low-density lipoprotein particle receptor activity;GO:0005044//scavenger receptor activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0015636//short-chain fatty acid transmembrane transporter activity;GO:0030169//low-density lipoprotein particle binding;GO:0035325//Toll-like receptor binding;GO:0044877//protein-containing complex binding;GO:0050431//transforming growth factor beta binding;GO:0070053//thrombospondin receptor activity;GO:0070892//lipoteichoic acid immune receptor activity;GO:0071813//lipoprotein particle binding;GO:0150025//oxidised low-density lipoprotein particle receptor activity;GO:1901480//oleate transmembrane transporter activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006869//lipid transport;GO:0006898//receptor-mediated endocytosis;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007263//nitric oxide mediated signal transduction;GO:0007596//blood coagulation;GO:0009617//response to bacterium;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010886//positive regulation of cholesterol storage;GO:0010942//positive regulation of cell death;GO:0015909//long-chain fatty acid transport;GO:0015911//long-chain fatty acid import across plasma membrane;GO:0015912//short-chain fatty acid transport;GO:0019915//lipid storage;GO:0019934//cGMP-mediated signaling;GO:0030194//positive regulation of blood coagulation;GO:0030299//intestinal cholesterol absorption;GO:0030301//cholesterol transport;GO:0031623//receptor internalization;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033993//response to lipid;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0034197//triglyceride transport;GO:0034381//plasma lipoprotein particle clearance;GO:0034383//low-density lipoprotein particle clearance;GO:0035634//response to stilbenoid;GO:0042308//negative regulation of protein import into nucleus;GO:0042953//lipoprotein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0043277//apoptotic cell clearance;GO:0043410//positive regulation of MAPK cascade;GO:0044539//long-chain fatty acid import into cell;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050830//defense response to Gram-positive bacterium;GO:0050892//intestinal absorption;GO:0050909//sensory perception of taste;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0060907//positive regulation of macrophage cytokine production;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070508//cholesterol import;GO:0070542//response to fatty acid;GO:0070543//response to linoleic acid;GO:0071221//cellular response to bacterial lipopeptide;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071447//cellular response to hydroperoxide;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0097009//energy homeostasis;GO:0098900//regulation of action potential;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0150024//oxidised low-density lipoprotein particle clearance;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904646//cellular response to amyloid-beta;GO:1990000//amyloid fibril formation;GO:1990379//lipid transport across blood-brain barrier;GO:2000121//regulation of removal of superoxide radicals;GO:2000334//positive regulation of blood microparticle formation;GO:2000379//positive regulation of reactive oxygen species metabolic process"	--
ENSG00000135220	0	0	0	0	0	0.04	0	0	0	0	0	1	UGT2A3	UDP glucuronosyltransferase family 2 member A3 [Source:HGNC Symbol;Acc:HGNC:28528]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0052695//cellular glucuronidation	--
ENSG00000135222	0	0	0	0	0	0	0	0	0	0	0	0	CSN2	casein beta [Source:HGNC Symbol;Acc:HGNC:2447]	Organismal Systems	Endocrine system	ko04917//Prolactin signaling pathway	K17107	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004857//enzyme inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006816//calcium ion transport;GO:0007595//lactation;GO:2000117//negative regulation of cysteine-type endopeptidase activity	--
ENSG00000135226	0	0	0	0	0.031	0	0	0	0	0	1	0	UGT2B28	UDP glucuronosyltransferase family 2 member B28 [Source:HGNC Symbol;Acc:HGNC:13479]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0008202//steroid metabolic process;GO:0052697//xenobiotic glucuronidation	--
ENSG00000135241	10.251	10.022	9.615	6.932	8.382	8.945	714	646	481	355	440	448	PNPLA8	patatin like phospholipase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28900]	-	-	-	-	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005524//ATP binding;GO:0008970//phospholipase A1 activity;GO:0016787//hydrolase activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008219//cell death;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0032048//cardiolipin metabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0043651//linoleic acid metabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0050482//arachidonic acid secretion;GO:0055088//lipid homeostasis;GO:0070328//triglyceride homeostasis;GO:1900407//regulation of cellular response to oxidative stress	--
ENSG00000135245	4.155	3.114	4.236	3.509	4.537	4.023	88	72	80	54	88	64	HILPDA	hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell population proliferation;GO:0010884//positive regulation of lipid storage;GO:0035425//autocrine signaling;GO:0071456//cellular response to hypoxia	--
ENSG00000135248	0.061	0	0	0	0.095	0	2	0	0	0	2	0	FAM71F1	family with sequence similarity 71 member F1 [Source:HGNC Symbol;Acc:HGNC:30704]	-	-	-	-	GO:0005794//Golgi apparatus	-	GO:0001675//acrosome assembly;GO:0007340//acrosome reaction	--
ENSG00000135249	6.294	4.326	4.76	4.087	4.025	5.083	320	257.92	182.96	150	154	172	RINT1	RAD50 interactor 1 [Source:HGNC Symbol;Acc:HGNC:21876]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0070939//Dsl1/NZR complex	GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060628//regulation of ER to Golgi vesicle-mediated transport"	--
ENSG00000135250	20.506	19.38	19.919	13.921	17.183	16.593	1376	1225	933	689	935	804	SRPK2	SRSF protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:11306]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	"GO:0000245//spliceosomal complex assembly;GO:0001525//angiogenesis;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0008284//positive regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0035063//nuclear speck organization;GO:0035556//intracellular signal transduction;GO:0043525//positive regulation of neuron apoptotic process;GO:0045070//positive regulation of viral genome replication;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045787//positive regulation of cell cycle;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0050684//regulation of mRNA processing;GO:0062176//R-loop disassembly"	--
ENSG00000135253	0.031	0.009	0	0.013	0	0	3	1	0	1	0	0	KCP	kielin cysteine rich BMP regulator [Source:HGNC Symbol;Acc:HGNC:17585]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0030513//positive regulation of BMP signaling pathway	--
ENSG00000135269	27.475	29.525	31.43	22.55	22.52	24.918	1508	1451	1036	857	959	929	TES	testin LIM domain protein [Source:HGNC Symbol;Acc:HGNC:14620]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0032991//protein-containing complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0008285//negative regulation of cell population proliferation;GO:0042127//regulation of cell population proliferation	--
ENSG00000135272	4.422	3.517	4.623	2.701	2.666	2.71	436	394	219	223	251	204	MDFIC	MyoD family inhibitor domain containing [Source:HGNC Symbol;Acc:HGNC:28870]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0030957//Tat protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0030111//regulation of Wnt signaling pathway;GO:0042308//negative regulation of protein import into nucleus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046328//regulation of JNK cascade;GO:0050434//positive regulation of viral transcription"	--
ENSG00000135297	8.585	6.752	7.884	6.705	5.557	8.231	476	379	321	283	267	322	MTO1	mitochondrial tRNA translation optimization 1 [Source:HGNC Symbol;Acc:HGNC:19261]	-	-	-	-	GO:0005739//mitochondrion	GO:0003723//RNA binding;GO:0050660//flavin adenine dinucleotide binding	GO:0002098//tRNA wobble uridine modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0070899//mitochondrial tRNA wobble uridine modification	--
ENSG00000135298	0.104	0.063	0	0.058	0.066	0.033	11	6	0	5	7	3	ADGRB3	adhesion G protein-coupled receptor B3 [Source:HGNC Symbol;Acc:HGNC:945]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043083//synaptic cleft;GO:0098794//postsynapse	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007520//myoblast fusion;GO:0016322//neuron remodeling;GO:0016525//negative regulation of angiogenesis;GO:0048814//regulation of dendrite morphogenesis;GO:0050790//regulation of catalytic activity;GO:0051965//positive regulation of synapse assembly;GO:0061743//motor learning;GO:0099558//maintenance of synapse structure	--
ENSG00000135299	10.033	8.837	7.962	6.435	8.17	8.619	837.57	706.18	489.35	398.66	557.2	495.46	ANKRD6	ankyrin repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:17280]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	"GO:0046330//positive regulation of JNK cascade;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000135312	0.056	0	0.076	0.025	0.022	0.052	3	0	3	1	1	2	HTR1B	5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse;ko04742//Taste transduction	K04153;K04153;K04153;K04153	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0044305//calyx of Held;GO:0098666//G protein-coupled serotonin receptor complex;GO:0099056//integral component of presynaptic membrane;GO:0099154//serotonergic synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding;GO:0099626//voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels;GO:1901363//heterocyclic compound binding	"GO:0002031//G protein-coupled receptor internalization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007610//behavior;GO:0007631//feeding behavior;GO:0014053//negative regulation of gamma-aminobutyric acid secretion;GO:0014059//regulation of dopamine secretion;GO:0014063//negative regulation of serotonin secretion;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0042220//response to cocaine;GO:0042310//vasoconstriction;GO:0042756//drinking behavior;GO:0045471//response to ethanol;GO:0046849//bone remodeling;GO:0050795//regulation of behavior;GO:0051385//response to mineralocorticoid;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0071312//cellular response to alkaloid;GO:0071466//cellular response to xenobiotic stimulus;GO:0071502//cellular response to temperature stimulus;GO:0098664//G protein-coupled serotonin receptor signaling pathway;GO:0099171//presynaptic modulation of chemical synaptic transmission;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000135314	3.529	3.378	4.738	4.29	3.412	5.564	98	94	92.5	90	83	109	KHDC1	KH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21366]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding	GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000135315	0.879	0.437	0.438	0.429	0.41	0.497	94	47	34	34	37	38	CEP162	centrosomal protein 162 [Source:HGNC Symbol;Acc:HGNC:21107]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005879//axonemal microtubule;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000135316	50.934	46.214	43.73	41.566	41.719	45.498	2953.84	2634.91	1841.08	1755.7	1980.89	1901.26	SYNCRIP	synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045293//mRNA editing complex;GO:0070937//CRD-mediated mRNA stability complex;GO:0071013//catalytic step 2 spliceosome;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0097452//GAIT complex;GO:0106002//mCRD-mediated mRNA stability complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0008380//RNA splicing;GO:0016556//mRNA modification;GO:0017148//negative regulation of translation;GO:0070934//CRD-mediated mRNA stabilization;GO:0071346//cellular response to interferon-gamma;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901537//positive regulation of DNA demethylation;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000135317	17.607	15.036	14.166	12.554	14.129	16.254	1195.91	1035.78	718.73	630.04	806.12	810.86	SNX14	sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031902//late endosome membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	"GO:0035091//phosphatidylinositol binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0015031//protein transport;GO:0097352//autophagosome maturation	--
ENSG00000135318	3.712	3.435	2.352	4.743	4.859	4.016	244	258	130	225	277	180	NT5E	5'-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K19970;K19970;K19970;K19970	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0008252//nucleotidase activity;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0006196//AMP catabolic process;GO:0006259//DNA metabolic process;GO:0007159//leukocyte cell-cell adhesion;GO:0009166//nucleotide catabolic process;GO:0010035//response to inorganic substance;GO:0016311//dephosphorylation;GO:0033198//response to ATP;GO:0046032//ADP catabolic process;GO:0046034//ATP metabolic process;GO:0046086//adenosine biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0055074//calcium ion homeostasis;GO:0110148//biomineralization	--
ENSG00000135324	0.271	0.449	0.122	0.305	0.24	0.248	12	20	4	10	9	8	MRAP2	melanocortin 2 receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:21232]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030545//signaling receptor regulator activity;GO:0031780//corticotropin hormone receptor binding;GO:0031781//type 3 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0031783//type 5 melanocortin receptor binding;GO:0042802//identical protein binding;GO:0070996//type 1 melanocortin receptor binding	GO:0006112//energy reserve metabolic process;GO:0007631//feeding behavior;GO:0072659//protein localization to plasma membrane;GO:0097009//energy homeostasis;GO:0106070//regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0106071//positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000135333	0.913	0.687	0.788	0.193	0.325	0.4	68	56	48	13	36	26	EPHA7	EPH receptor A7 [Source:HGNC Symbol;Acc:HGNC:3390]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05108	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0045499//chemorepellent activity;GO:0046875//ephrin receptor binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0022407//regulation of cell-cell adhesion;GO:0031290//retinal ganglion cell axon guidance;GO:0031952//regulation of protein autophosphorylation;GO:0033674//positive regulation of kinase activity;GO:0043065//positive regulation of apoptotic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0048013//ephrin receptor signaling pathway;GO:0048671//negative regulation of collateral sprouting;GO:0048755//branching morphogenesis of a nerve;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050919//negative chemotaxis;GO:0051964//negative regulation of synapse assembly;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0072178//nephric duct morphogenesis;GO:0099175//regulation of postsynapse organization	--
ENSG00000135334	24.461	25.246	26.035	28.359	30.577	30.687	963	999	757	827	1017	879	AKIRIN2	akirin 2 [Source:HGNC Symbol;Acc:HGNC:21407]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0008284//positive regulation of cell population proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0010629//negative regulation of gene expression;GO:0010950//positive regulation of endopeptidase activity;GO:0032496//response to lipopolysaccharide;GO:0032755//positive regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000135336	11.713	10.25	10.35	7.802	7.95	7.055	607	534	396	279	348	266	ORC3	origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02605	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005656//nuclear pre-replicative complex;GO:0005664//nuclear origin of replication recognition complex;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0031261//DNA replication preinitiation complex"	GO:0003677//DNA binding;GO:0003688//DNA replication origin binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0006275//regulation of DNA replication;GO:0061351//neural precursor cell proliferation	--
ENSG00000135338	4.384	3.16	3.147	1.939	1.494	2.199	416	301	220	136	120	152	LCA5	lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0015031//protein transport;GO:0042073//intraciliary transport;GO:0045494//photoreceptor cell maintenance	--
ENSG00000135341	9.273	9.289	7.518	6.137	7.47	7.808	927	925	558	451	622	569	MAP3K7	mitogen-activated protein kinase kinase kinase 7 [Source:HGNC Symbol;Acc:HGNC:6859]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Signal transduction;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cardiovascular disease;Development and regeneration;Signal transduction;Signal transduction;Infectious disease: parasitic;Immune system;Immune system;Immune system;Cellular community - eukaryotes;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04310//Wnt signaling pathway;ko05161//Hepatitis B;ko04140//Autophagy - animal;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04152//AMPK signaling pathway;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko04520//Adherens junction;ko04622//RIG-I-like receptor signaling pathway	K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427;K04427	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008385//IkappaB kinase complex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0140672//ATAC complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030971//receptor tyrosine kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002726//positive regulation of T cell cytokine production;GO:0002753//cytoplasmic pattern recognition receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007252//I-kappaB phosphorylation;GO:0007254//JNK cascade;GO:0016239//positive regulation of macroautophagy;GO:0016310//phosphorylation;GO:0032743//positive regulation of interleukin-2 production;GO:0038066//p38MAPK cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043276//anoikis;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0043966//histone H3 acetylation;GO:0050852//T cell receptor signaling pathway;GO:0050896//response to stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051403//stress-activated MAPK cascade;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway	--
ENSG00000135346	0	0	0	0	0.08	0	0	0	0	0	1	0	CGA	"glycoprotein hormones, alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:1885]"	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune disease;Endocrine system;Endocrine system;Endocrine system;Endocrine system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05320//Autoimmune thyroid disease;ko04912//GnRH signaling pathway;ko04917//Prolactin signaling pathway;ko04918//Thyroid hormone synthesis;ko04929//GnRH secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis	K08522;K08522;K08522;K08522;K08522;K08522;K08522;K08522;K08522	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0016914//follicle-stimulating hormone complex;GO:0061696//pituitary gonadotropin complex	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0016913//follicle-stimulating hormone activity	GO:0006590//thyroid hormone generation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008406//gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0010469//regulation of signaling receptor activity;GO:0010893//positive regulation of steroid biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0030878//thyroid gland development;GO:0032275//luteinizing hormone secretion;GO:0032870//cellular response to hormone stimulus;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046621//negative regulation of organ growth;GO:0046884//follicle-stimulating hormone secretion;GO:0048589//developmental growth	--
ENSG00000135355	0	0	0	0	0	0	0	0	0	0	0	0	GJA10	gap junction protein alpha 10 [Source:HGNC Symbol;Acc:HGNC:16995]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007276//gamete generation;GO:0007416//synapse assembly;GO:0009416//response to light stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0055085//transmembrane transport	--
ENSG00000135362	1.069	0.645	0.266	1.271	1.427	1.41	38	41	16	62	40	34	PRR5L	proline rich 5 like [Source:HGNC Symbol;Acc:HGNC:25878]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20411	GO:0031932//TORC2 complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0009968//negative regulation of signal transduction;GO:0010762//regulation of fibroblast migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0034599//cellular response to oxidative stress;GO:0038203//TORC2 signaling;GO:0061014//positive regulation of mRNA catabolic process;GO:0090316//positive regulation of intracellular protein transport	--
ENSG00000135363	0	0.032	0	0	0	0	0	1	0	0	0	0	LMO2	LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15612	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	GO:0001221//transcription coregulator binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043425//bHLH transcription factor binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097067//cellular response to thyroid hormone stimulus	--
ENSG00000135365	9.606	7.803	6.977	5.78	6.795	7.748	674	620	446	376	503	433	PHF21A	PHD finger protein 21A [Source:HGNC Symbol;Acc:HGNC:24156]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990391//DNA repair complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization	--
ENSG00000135372	13.251	14.149	15.878	13.335	14.607	11.172	1092	1172	927	814	1017	665	NAT10	N-acetyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:29830]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14521	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0016020//membrane;GO:0030496//midbody"	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0070182//DNA polymerase binding;GO:0106162//mRNA N-acetyltransferase activity;GO:1990883//rRNA cytidine N-acetyltransferase activity	GO:0000154//rRNA modification;GO:0006364//rRNA processing;GO:0006473//protein acetylation;GO:0006807//nitrogen compound metabolic process;GO:0008033//tRNA processing;GO:0010824//regulation of centrosome duplication;GO:0016072//rRNA metabolic process;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0034470//ncRNA processing;GO:0042274//ribosomal small subunit biogenesis;GO:0043412//macromolecule modification;GO:0044238//primary metabolic process;GO:0045727//positive regulation of translation;GO:0051391//tRNA acetylation;GO:1904812//rRNA acetylation involved in maturation of SSU-rRNA	--
ENSG00000135373	0.045	0	0.078	0	0.056	0.025	5	0	3	0	3	2	EHF	ETS homologous factor [Source:HGNC Symbol;Acc:HGNC:3246]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030855//epithelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050673//epithelial cell proliferation"	ETS
ENSG00000135374	0	0	0	0	0	0	0	0	0	0	0	0	ELF5	E74 like ETS transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3320]	Organismal Systems	Endocrine system	ko04917//Prolactin signaling pathway	K17101	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	ETS
ENSG00000135378	0.235	0.242	0.188	0.141	0.124	0.12	27	28	16	12	12	10	PRRG4	proline rich and Gla domain 4 [Source:HGNC Symbol;Acc:HGNC:30799]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0008150//biological_process	--
ENSG00000135387	87.568	81.532	79.106	68.246	69.234	73.86	7261	6831	4911	4123	4846	4426	CAPRIN1	cell cycle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6743]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030425//dendrite;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0045202//synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0050775//positive regulation of dendrite morphogenesis;GO:0061003//positive regulation of dendritic spine morphogenesis	--
ENSG00000135390	121.59	133.906	150.233	181.897	147.429	156.316	1601	1770	1460	1769	1639	1499	ATP5MC2	ATP synthase membrane subunit c locus 2 [Source:HGNC Symbol;Acc:HGNC:842]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015078//proton transmembrane transporter activity	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:1902600//proton transmembrane transport	--
ENSG00000135392	15.458	15.68	16.177	15.272	17.203	18.184	1052.48	1077.17	824.51	765.91	987.75	908.31	DNAJC14	DnaJ heat shock protein family (Hsp40) member C14 [Source:HGNC Symbol;Acc:HGNC:24581]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0015031//protein transport	--
ENSG00000135404	1039.883	1061.142	1158.034	1306.253	1109.799	1246.486	21192	21803	17557	19725	19739	18560	CD63	CD63 molecule [Source:HGNC Symbol;Acc:HGNC:1692]	Human Diseases;Cellular Processes	Cancer: overview;Transport and catabolism	ko05205//Proteoglycans in cancer;ko04142//Lysosome	K06497;K06497	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031088//platelet dense granule membrane;GO:0031226//intrinsic component of plasma membrane;GO:0031902//late endosome membrane;GO:0031904//endosome lumen;GO:0032585//multivesicular body membrane;GO:0035577//azurophil granule membrane;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0097487//multivesicular body, internal vesicle"	GO:0005515//protein binding	GO:0002092//positive regulation of receptor internalization;GO:0007160//cell-matrix adhesion;GO:0015031//protein transport;GO:0016477//cell migration;GO:0034613//cellular protein localization;GO:0035646//endosome to melanosome transport;GO:0043473//pigmentation;GO:0048757//pigment granule maturation;GO:0050931//pigment cell differentiation;GO:1900746//regulation of vascular endothelial growth factor signaling pathway;GO:1901379//regulation of potassium ion transmembrane transport;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000135406	6.517	6.084	6.691	11.083	9.511	14.325	228	214	170	301	294	356	PRPH	peripherin [Source:HGNC Symbol;Acc:HGNC:9461]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K07607;K07607	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045098//type III intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000135407	0.219	0.142	0.085	0.169	0.148	0.17	14	9	4	8	8	7	AVIL	advillin [Source:HGNC Symbol;Acc:HGNC:14188]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043005//neuron projection	"GO:0003779//actin binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0051015//actin filament binding;GO:0071933//Arp2/3 complex binding"	GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0007399//nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0010592//positive regulation of lamellipodium assembly;GO:0010976//positive regulation of neuron projection development;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping;GO:0060271//cilium assembly;GO:1900480//regulation of diacylglycerol biosynthetic process	--
ENSG00000135409	0.024	0	0.074	0	0	0.224	1	0	1	0	0	3	AMHR2	anti-Mullerian hormone receptor type 2 [Source:HGNC Symbol;Acc:HGNC:465]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04350//TGF-beta signaling pathway	K04672;K04672	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0048179//activin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005026//transforming growth factor beta receptor activity, type II;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017002//activin-activated receptor activity;GO:0042562//hormone binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:1990272//anti-Mullerian hormone receptor activity"	GO:0001880//Mullerian duct regression;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007548//sex differentiation;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0016310//phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:1990262//anti-Mullerian hormone signaling pathway	--
ENSG00000135413	0	0	0	0	0	0	0	0	0	0	0	0	LACRT	lacritin [Source:HGNC Symbol;Acc:HGNC:16430]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008083//growth factor activity;GO:0043237//laminin-1 binding;GO:0047485//protein N-terminus binding	GO:0006473//protein acetylation;GO:0008284//positive regulation of cell population proliferation;GO:0010669//epithelial structure maintenance;GO:0016239//positive regulation of macroautophagy;GO:0019722//calcium-mediated signaling;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0034067//protein localization to Golgi apparatus;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0051047//positive regulation of secretion;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0070075//tear secretion;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000135414	64.44	64.421	70.08	69.53	69.122	61.949	7608.42	7273	6126.23	5598.73	6208.08	5321.44	GDF11	growth differentiation factor 11 [Source:HGNC Symbol;Acc:HGNC:4216]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22679	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001501//skeletal system development;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007498//mesoderm development;GO:0008285//negative regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0021512//spinal cord anterior/posterior patterning;GO:0031016//pancreas development;GO:0045596//negative regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0048469//cell maturation;GO:0048593//camera-type eye morphogenesis;GO:0060021//roof of mouth development;GO:0060395//SMAD protein signal transduction	--
ENSG00000135423	12.89	14.352	15.541	13.424	14.133	14.838	630.61	690.22	560.72	486.64	558.99	541.27	GLS2	glutaminase 2 [Source:HGNC Symbol;Acc:HGNC:29570]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Nervous system;Nervous system;Cancer: overview;Amino acid metabolism;Excretory system;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko04724//Glutamatergic synapse;ko04727//GABAergic synapse;ko05230//Central carbon metabolism in cancer;ko00250//Alanine, aspartate and glutamate metabolism;ko04964//Proximal tubule bicarbonate reclamation;ko00220//Arginine biosynthesis;ko00470//D-Amino acid metabolism"	K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004359//glutaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006520//cellular amino acid metabolic process;GO:0006537//glutamate biosynthetic process;GO:0006541//glutamine metabolic process;GO:0006543//glutamine catabolic process;GO:0042981//regulation of apoptotic process;GO:0072593//reactive oxygen species metabolic process	--
ENSG00000135424	30.158	35.246	39.214	38.691	41.407	48.688	2547	2963	2419	2434	2928	2963	ITGA7	integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06583;K06583;K06583;K06583;K06583;K06583;K06583;K06583	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0043236//laminin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0008360//regulation of cell shape;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0035987//endodermal cell differentiation;GO:0050900//leukocyte migration;GO:0098609//cell-cell adhesion	--
ENSG00000135426	0	0	0	0	0	0	0	0	0	0	0	0	TESPA1	"thymocyte expressed, positive selection associated 1 [Source:HGNC Symbol;Acc:HGNC:29109]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0016020//membrane;GO:0036398//TCR signalosome	GO:0005102//signaling receptor binding;GO:0043274//phospholipase binding	GO:0008104//protein localization;GO:0010387//COP9 signalosome assembly;GO:0033077//T cell differentiation in thymus;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0036399//TCR signalosome assembly;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway	--
ENSG00000135436	0.307	0.212	0.222	0.231	0.159	0.121	18	13	10	10	8	5	FAM186B	family with sequence similarity 186 member B [Source:HGNC Symbol;Acc:HGNC:25296]	-	-	-	-	GO:0032991//protein-containing complex	-	-	--
ENSG00000135437	166.082	167.512	232.458	359.832	295.855	298.31	4147.29	4193.84	4299.52	6680.26	6202.18	5454.85	RDH5	retinol dehydrogenase 5 [Source:HGNC Symbol;Acc:HGNC:9940]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K00061;K00061	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044297//cell body	"GO:0004745//NAD-retinol dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity;GO:0047023//androsterone dehydrogenase activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0007601//visual perception;GO:0008202//steroid metabolic process;GO:0042572//retinol metabolic process;GO:0050896//response to stimulus	--
ENSG00000135439	0.143	0.123	0.029	0.103	0.122	0.061	9	4	2	8	10	5	AGAP2	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:HGNC:16921]"	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04068//FoxO signaling pathway	K17848;K17848	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0090543//Flemming body	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0046872//metal ion binding	GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030036//actin cytoskeleton organization;GO:0032147//activation of protein kinase activity;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050790//regulation of catalytic activity;GO:0060749//mammary gland alveolus development;GO:0061903//positive regulation of 1-phosphatidylinositol-3-kinase activity;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000135441	25.959	31.42	26.645	36.592	31.179	32.694	307.22	376.33	237.11	320.44	315.53	289.61	BLOC1S1	biogenesis of lysosomal organelles complex 1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:4200]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031083//BLOC-1 complex;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0008089//anterograde axonal transport;GO:0009060//aerobic respiration;GO:0016197//endosomal transport;GO:0018394//peptidyl-lysine acetylation;GO:0031175//neuron projection development;GO:0032418//lysosome localization;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0051036//regulation of endosome size;GO:0051641//cellular localization;GO:0060155//platelet dense granule organization;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule	--
ENSG00000135443	0	0	0	0	0	0	0	0	0	0	0	0	KRT85	keratin 85 [Source:HGNC Symbol;Acc:HGNC:6462]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008544//epidermis development	--
ENSG00000135446	66.782	71.479	69.652	83.007	74.683	66.905	1958.28	2149.88	1605.61	1866.98	1806.29	1556.01	CDK4	cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cellular community - eukaryotes;Cancer: specific types;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko04530//Tight junction;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05162//Measles;ko04110//Cell cycle;ko04660//T cell receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko04115//p53 signaling pathway;ko05219//Bladder cancer	K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089;K02089	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016592//mediator complex;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0097128//cyclin D1-CDK4 complex;GO:0097129//cyclin D2-CDK4 complex;GO:0097130//cyclin D3-CDK4 complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010468//regulation of gene expression;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016310//phosphorylation;GO:0032869//cellular response to insulin stimulus;GO:0040014//regulation of multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046890//regulation of lipid biosynthetic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0050790//regulation of catalytic activity;GO:0050994//regulation of lipid catabolic process;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060260//regulation of transcription initiation from RNA polymerase II promoter;GO:0060612//adipose tissue development;GO:0071222//cellular response to lipopolysaccharide;GO:0071353//cellular response to interleukin-4;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:1904637//cellular response to ionomycin	--
ENSG00000135447	0.712	1.107	0.741	1.183	0.621	0.652	27	33	21	21	16	18	PPP1R1A	protein phosphatase 1 regulatory inhibitor subunit 1A [Source:HGNC Symbol;Acc:HGNC:9286]	Organismal Systems;Organismal Systems	Circulatory system;Nervous system	ko04261//Adrenergic signaling in cardiomyocytes;ko04720//Long-term potentiation	K08050;K08050	GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity	--
ENSG00000135451	0.716	0.189	0.391	0.258	0.539	1.269	15	10	8	11	17	26	TROAP	trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007155//cell adhesion	--
ENSG00000135452	27.121	27.631	29.808	29.829	25.193	31.492	818.72	892.12	700.39	656.02	664.71	676.99	TSPAN31	tetraspanin 31 [Source:HGNC Symbol;Acc:HGNC:10539]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008284//positive regulation of cell population proliferation	--
ENSG00000135454	0.296	0.32	0.12	0.166	0.021	0.106	14	10	6	4	2	3	B4GALNT1	"beta-1,4-N-acetyl-galactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4117]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K00725;K00725	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0003947//(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0001574//ganglioside biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0007283//spermatogenesis;GO:0019915//lipid storage;GO:0030259//lipid glycosylation	--
ENSG00000135457	7.493	7.435	8.345	9.105	8.702	7.755	455	461	313	345	416	301	TFCP2	transcription factor CP2 [Source:HGNC Symbol;Acc:HGNC:11748]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008134//transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	CP2
ENSG00000135469	11.876	10.651	11.646	12.349	12.325	13.619	357	320	257	273	287	293	COQ10A	coenzyme Q10A [Source:HGNC Symbol;Acc:HGNC:26515]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0048039//ubiquinone binding	GO:0006744//ubiquinone biosynthetic process;GO:0045333//cellular respiration	--
ENSG00000135472	0.171	0.064	0.082	0.066	0.037	0.112	5	3	2	1	3	3	FAIM2	Fas apoptotic inhibitory molecule 2 [Source:HGNC Symbol;Acc:HGNC:17067]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	GO:0002931//response to ischemia;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0021549//cerebellum development;GO:0021680//cerebellar Purkinje cell layer development;GO:0021681//cerebellar granular layer development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000135473	6.858	7.024	8.263	8.383	8.976	7.755	652	667	561	551	717	512	PAN2	poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12571	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031251//PAN complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006397//mRNA processing;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000135476	0.189	0.268	0.67	0.285	0.345	0.578	26	37	21	29	40	27	ESPL1	"extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856]"	Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Cell growth and death;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04114//Oocyte meiosis;ko04110//Cell cycle	K02365;K02365;K02365	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0072686//mitotic spindle	GO:0003824//catalytic activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000070//mitotic sister chromatid segregation;GO:0000212//meiotic spindle organization;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007059//chromosome segregation;GO:0007127//meiosis I;GO:0040001//establishment of mitotic spindle localization;GO:0045143//homologous chromosome segregation;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0045875//negative regulation of sister chromatid cohesion;GO:0051307//meiotic chromosome separation	--
ENSG00000135480	122.798	125.299	89.54	131.334	154.619	132.643	4139	4245	2229	3279	4403	3253	KRT7	keratin 7 [Source:HGNC Symbol;Acc:HGNC:6445]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000135482	1.66	1.949	1.954	2.221	1.875	1.825	212	222	195	204	200	163	ZC3H10	zinc finger CCCH-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25893]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0010608//posttranscriptional regulation of gene expression;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA"	--
ENSG00000135486	779.303	785.086	752.922	786.008	705.895	685.267	23111.22	23034.15	16539.04	16582.37	18184.61	14520.18	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1 [Source:HGNC Symbol;Acc:HGNC:5031]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12741;K12741	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0035198//miRNA binding;GO:0036002//pre-mRNA binding;GO:0042802//identical protein binding;GO:0061752//telomeric repeat-containing RNA binding;GO:0098505//G-rich strand telomeric DNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006405//RNA export from nucleus;GO:0008380//RNA splicing;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0042149//cellular response to glucose starvation;GO:0043484//regulation of RNA splicing;GO:0051028//mRNA transport;GO:0051168//nuclear export;GO:0051170//import into nucleus;GO:1903936//cellular response to sodium arsenite"	--
ENSG00000135503	9.956	10.504	9.409	9.71	10.861	9.84	915	929	648	676	822	669	ACVR1B	activin A receptor type 1B [Source:HGNC Symbol;Acc:HGNC:172]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K13567;K13567;K13567	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0048179//activin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016361//activin receptor activity, type I;GO:0016740//transferase activity;GO:0017002//activin-activated receptor activity;GO:0019838//growth factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0034711//inhibin binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048185//activin binding"	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0001701//in utero embryonic development;GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007399//nervous system development;GO:0009966//regulation of signal transduction;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030308//negative regulation of cell growth;GO:0032924//activin receptor signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0038092//nodal signaling pathway;GO:0045648//positive regulation of erythrocyte differentiation;GO:0046777//protein autophosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901165//positive regulation of trophoblast cell migration"	--
ENSG00000135506	138.445	157.021	141.462	144.982	142.698	136.411	7296	8239	5526	5635	6293	5202	OS9	OS9 endoplasmic reticulum lectin [Source:HGNC Symbol;Acc:HGNC:16994]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10088	GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane	GO:0002020//protease binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006605//protein targeting;GO:0006621//protein retention in ER lumen;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0034976//response to endoplasmic reticulum stress;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000135517	0	0	0	0.124	0	0	0	0	0	5	0	0	MIP	major intrinsic protein of lens fiber [Source:HGNC Symbol;Acc:HGNC:7103]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015250//water channel activity;GO:0015267//channel activity	GO:0002088//lens development in camera-type eye;GO:0006833//water transport;GO:0007601//visual perception;GO:0045785//positive regulation of cell adhesion;GO:0050896//response to stimulus;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000135519	0	0.062	0.034	0.017	0.043	0.068	0	5	2	1	3	4	KCNH3	potassium voltage-gated channel subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:6252]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000135521	5.724	5.617	5.848	3.442	3.757	5.292	220	217	166	98	122	148	LTV1	LTV1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:21173]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor"	GO:0005515//protein binding	GO:0000056//ribosomal small subunit export from nucleus;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000135525	18.574	17.332	18.679	17.239	16.86	19.451	1363	1307	1026	952	1074	1030	MAP7	microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030424//axon;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0006970//response to osmotic stress;GO:0007163//establishment or maintenance of cell polarity;GO:0072659//protein localization to plasma membrane	--
ENSG00000135535	146.583	133.438	144.852	121.341	119.987	141.796	9172	8392	6696	5620	6343	6454	CD164	CD164 molecule [Source:HGNC Symbol;Acc:HGNC:1632]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K06546	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0030097//hemopoiesis	--
ENSG00000135537	1.535	0.761	0.506	0.836	1.901	0.734	107	72	37	54	72	54	AFG1L	AFG1 like ATPase [Source:HGNC Symbol;Acc:HGNC:16411]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0007005//mitochondrion organization;GO:0035694//mitochondrial protein catabolic process"	--
ENSG00000135540	19.977	22.109	22.116	14.795	15.947	17.961	2214	2249	1649	1121	1564	1378	NHSL1	NHS like 1 [Source:HGNC Symbol;Acc:HGNC:21021]	-	-	-	-	-	-	GO:0030154//cell differentiation	--
ENSG00000135541	3.252	2.387	2.365	1.199	1.387	2.179	295	232	148	68	116	144	AHI1	Abelson helper integration site 1 [Source:HGNC Symbol;Acc:HGNC:21575]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005929//cilium;GO:0030054//cell junction;GO:0036038//MKS complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097730//non-motile cilium	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001738//morphogenesis of a polarized epithelium;GO:0001947//heart looping;GO:0002092//positive regulation of receptor internalization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007417//central nervous system development;GO:0010842//retina layer formation;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0030862//positive regulation of polarized epithelial cell differentiation;GO:0030902//hindbrain development;GO:0034613//cellular protein localization;GO:0035844//cloaca development;GO:0035845//photoreceptor cell outer segment organization;GO:0039008//pronephric nephron tubule morphogenesis;GO:0039023//pronephric duct morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050795//regulation of behavior;GO:0060271//cilium assembly;GO:0065001//specification of axis polarity;GO:0070121//Kupffer's vesicle development;GO:0070986//left/right axis specification;GO:0071599//otic vesicle development	--
ENSG00000135547	0	0.097	0.053	0	0.022	0	0	5	2	0	1	0	HEY2	hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05224//Breast cancer;ko04330//Notch signaling pathway	K09091;K09091;K09091;K09091	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0003150//muscular septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003161//cardiac conduction system development;GO:0003171//atrioventricular valve development;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0003195//tricuspid valve formation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0003208//cardiac ventricle morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003300//cardiac muscle hypertrophy;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007389//pattern specification process;GO:0007507//heart development;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0010460//positive regulation of heart rate;GO:0010468//regulation of gene expression;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014031//mesenchymal cell development;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0035910//ascending aorta morphogenesis;GO:0035912//dorsal aorta morphogenesis;GO:0036304//umbilical cord morphogenesis;GO:0045165//cell fate commitment;GO:0045607//regulation of inner ear auditory receptor cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0051145//smooth muscle cell differentiation;GO:0055015//ventricular cardiac muscle cell development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060347//heart trabecula formation;GO:0060411//cardiac septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0060716//labyrinthine layer blood vessel development;GO:0060840//artery development;GO:0060842//arterial endothelial cell differentiation;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060977//coronary vasculature morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0065004//protein-DNA complex assembly;GO:0070168//negative regulation of biomineral tissue development;GO:0072359//circulatory system development;GO:0090102//cochlea development;GO:0097084//vascular associated smooth muscle cell development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2000723//negative regulation of cardiac vascular smooth muscle cell differentiation;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:2001212//regulation of vasculogenesis"	bHLH
ENSG00000135549	10.407	9.041	10.692	9.969	11.11	12.259	311	268	227	221	274	266	PKIB	cAMP-dependent protein kinase inhibitor beta [Source:HGNC Symbol;Acc:HGNC:9018]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051338//regulation of transferase activity;GO:0051973//positive regulation of telomerase activity;GO:1904355//positive regulation of telomere capping;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000135569	0	0	0	0	0	0	0	0	0	0	0	0	TAAR5	trace amine associated receptor 5 [Source:HGNC Symbol;Acc:HGNC:30236]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:1990081//trimethylamine receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus	--
ENSG00000135577	0	0.016	0	0.021	0.019	0	0	1	0	1	1	0	NMBR	neuromedin B receptor [Source:HGNC Symbol;Acc:HGNC:7843]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04168	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004946//bombesin receptor activity;GO:0008188//neuropeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0031989//bombesin receptor signaling pathway	--
ENSG00000135587	4.82	5.655	3.995	6.47	6.907	7.036	157.96	183.51	103.07	153.78	177.11	165.4	SMPD2	sphingomyelin phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:11121]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K12351;K12351;K12351	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071944//cell periphery	GO:0003824//catalytic activity;GO:0004620//phospholipase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0006807//nitrogen compound metabolic process;GO:0030149//sphingolipid catabolic process;GO:0044238//primary metabolic process;GO:0046513//ceramide biosynthetic process;GO:0071704//organic substance metabolic process	--
ENSG00000135596	4.091	4.67	4.833	4.649	4.443	4.617	290	331	253	245	264	239	MICAL1	"microtubule associated monooxygenase, calponin and LIM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20619]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:1990026//hippocampal mossy fiber expansion	"GO:0003779//actin binding;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0071949//FAD binding"	GO:0001933//negative regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0019417//sulfur oxidation;GO:0030042//actin filament depolymerization;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051017//actin filament bundle assembly;GO:1903305//regulation of regulated secretory pathway	--
ENSG00000135597	12.927	12.476	11.839	11.654	11.415	12.613	737.92	698	514.94	460	556	495	REPS1	RALBP1 associated Eps domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15578]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0016197//endosomal transport	--
ENSG00000135604	0.07	0.2	0.154	0.13	0.104	0.144	8	23	13	11	10	12	STX11	syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08487	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0048787//presynaptic active zone membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0048278//vesicle docking;GO:0061025//membrane fusion	--
ENSG00000135605	0.802	0.655	0.351	0.48	0.39	0.592	45	50	19	27	25	31	TEC	tec protein tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11719]	Organismal Systems;Organismal Systems	Development and regeneration;Immune system	ko04380//Osteoclast differentiation;ko04660//T cell receptor signaling pathway	K07364;K07364	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0007229//integrin-mediated signaling pathway;GO:0010543//regulation of platelet activation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035556//intracellular signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042246//tissue regeneration;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway	--
ENSG00000135617	10.925	11.749	8.564	9.017	8.586	9.301	247	267	143	151	164	153	PRADC1	protease associated domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16047]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000135622	7.107	9.496	9.857	7.029	9.045	7.04	431	566	422	334	444	329	SEMA4F	ssemaphorin 4F [Source:HGNC Symbol;Acc:HGNC:10734]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0031290//retinal ganglion cell axon guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000135624	102.244	104.35	105.847	107.378	101.884	110.253	3907	3975	2964	3032	3265	3068	CCT7	chaperonin containing TCP1 subunit 7 [Source:HGNC Symbol;Acc:HGNC:1622]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005874//microtubule;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0042026//protein refolding;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000135625	0	0	0	0	0	0	0	0	0	0	0	0	EGR4	early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000135631	14.622	15.355	16.256	17.843	16.666	17.019	1488	1573	1223	1371	1429	1261	RAB11FIP5	RAB11 family interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:24845]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12484	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031966//mitochondrial membrane;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0043015//gamma-tubulin binding	GO:0015031//protein transport;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0045055//regulated exocytosis;GO:0065008//regulation of biological quality;GO:0070164//negative regulation of adiponectin secretion;GO:0071468//cellular response to acidic pH;GO:2000008//regulation of protein localization to cell surface	--
ENSG00000135632	8.762	11.763	10.687	11.969	12.338	12.399	457	591	404	422	546	439	SMYD5	SMYD family member 5 [Source:HGNC Symbol;Acc:HGNC:16258]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0046872//metal ion binding	"GO:0010529//negative regulation of transposition;GO:0032259//methylation;GO:0034773//histone H4-K20 trimethylation;GO:0034968//histone lysine methylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:2000035//regulation of stem cell division;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000135636	1.273	0.953	0.498	0.505	0.715	0.354	175	134	52	51	84	36	DYSF	dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0030315//T-tubule;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034451//centriolar satellite;GO:0042383//sarcolemma;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0046872//metal ion binding	GO:0001778//plasma membrane repair;GO:0002280//monocyte activation involved in immune response;GO:0002281//macrophage activation involved in immune response;GO:0006906//vesicle fusion;GO:0007009//plasma membrane organization;GO:0033292//T-tubule organization;GO:0050765//negative regulation of phagocytosis;GO:0061025//membrane fusion	--
ENSG00000135637	1.839	1.891	2.2	1.372	2.068	2.268	134.32	125.85	123.7	83	128.56	113.63	CCDC142	coiled-coil domain containing 142 [Source:HGNC Symbol;Acc:HGNC:25889]	-	-	-	-	-	-	-	--
ENSG00000135638	0	0	0	0	0.027	0	0	0	0	0	1	0	EMX1	empty spiracles homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3340]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0009410//response to xenobiotic stimulus;GO:0009791//post-embryonic development;GO:0021537//telencephalon development;GO:0021796//cerebral cortex regionalization;GO:0021895//cerebral cortex neuron differentiation;GO:0021987//cerebral cortex development;GO:0030182//neuron differentiation;GO:0048854//brain morphogenesis;GO:0048872//homeostasis of number of cells;GO:0060019//radial glial cell differentiation;GO:0060563//neuroepithelial cell differentiation;GO:0070445//regulation of oligodendrocyte progenitor proliferation;GO:1990138//neuron projection extension"	Homeobox
ENSG00000135643	0.399	0.722	0.291	0.235	0.411	0.211	39	71	21	17	34	15	KCNMB4	potassium calcium-activated channel subfamily M regulatory beta subunit 4 [Source:HGNC Symbol;Acc:HGNC:6289]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K04941;K04941;K04941	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0015459//potassium channel regulator activity	GO:0001508//action potential;GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0019228//neuronal action potential;GO:0019229//regulation of vasoconstriction;GO:0046928//regulation of neurotransmitter secretion;GO:0071805//potassium ion transmembrane transport	--
ENSG00000135655	7.183	5.028	4.606	5.18	4.76	7.394	481	378	203	179	276	285	USP15	ubiquitin specific peptidase 15 [Source:HGNC Symbol;Acc:HGNC:12613]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K21343	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003824//catalytic activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0061649//ubiquitin modification-dependent histone binding;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016579//protein deubiquitination;GO:0030509//BMP signaling pathway;GO:0035520//monoubiquitinated protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0071108//protein K48-linked deubiquitination;GO:1900246//positive regulation of RIG-I signaling pathway;GO:1905035//negative regulation of antifungal innate immune response;GO:1990167//protein K27-linked deubiquitination	--
ENSG00000135677	345.994	356.672	357.299	348.882	361.157	374.052	34466	35850	26215	26135	30310	26591	GNS	glucosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4422]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01137;K01137;K01137	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0043199//sulfate binding;GO:0046872//metal ion binding	GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0042340//keratan sulfate catabolic process	--
ENSG00000135678	1.132	1.377	2.403	1.664	1.339	1.242	96	89	59	62	68	69	CPM	carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0016485//protein processing	--
ENSG00000135679	5.982	5.383	5.659	3.945	3.775	5.146	654	598	409	317	392	362	MDM2	MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Genetic Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	"Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: overview;Cell growth and death;Folding, sorting and degradation;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cancer: specific types"	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko04218//Cellular senescence;ko04120//Ubiquitin mediated proteolysis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05219//Bladder cancer	K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643;K06643	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0017053//transcription repressor complex;GO:0030666//endocytic vesicle membrane;GO:0032991//protein-containing complex	GO:0002039//p53 binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008097//5S rRNA binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0019789//SUMO transferase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0061630//ubiquitin protein ligase activity;GO:0061663//NEDD8 ligase activity;GO:0097718//disordered domain specific binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0001568//blood vessel development;GO:0001974//blood vessel remodeling;GO:0002027//regulation of heart rate;GO:0003170//heart valve development;GO:0003181//atrioventricular valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007089//traversing start control point of mitotic cell cycle;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0031648//protein destabilization;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034504//protein localization to nucleus;GO:0036369//transcription factor catabolic process;GO:0042176//regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045184//establishment of protein localization;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle;GO:0046677//response to antibiotic;GO:0051149//positive regulation of muscle cell differentiation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0051726//regulation of cell cycle;GO:0051865//protein autoubiquitination;GO:0060411//cardiac septum morphogenesis;GO:0065003//protein-containing complex assembly;GO:0065008//regulation of biological quality;GO:0071456//cellular response to hypoxia;GO:0071480//cellular response to gamma radiation;GO:0072717//cellular response to actinomycin D;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1990000//amyloid fibril formation"	--
ENSG00000135686	9.074	8.566	9.525	9.256	9.723	9.25	1311	1350	1103	1075	1232	1053	KLHL36	kelch like family member 36 [Source:HGNC Symbol;Acc:HGNC:17844]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0008150//biological_process;GO:0016567//protein ubiquitination	--
ENSG00000135697	25.786	26.775	24.406	26.404	21.65	26.124	1159	1242	787	869	903	826	BCO1	beta-carotene oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:13815]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K00515;K00515	GO:0005829//cytosol	"GO:0003834//beta-carotene 15,15'-dioxygenase activity;GO:0010436//carotenoid dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0016121//carotene catabolic process;GO:0035238//vitamin A biosynthetic process;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:1901810//beta-carotene metabolic process	--
ENSG00000135698	10.094	10.122	12.676	10.877	10.273	8.83	219	219	201	184	184	142	MPHOSPH6	M-phase phosphoprotein 6 [Source:HGNC Symbol;Acc:HGNC:7214]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12593	GO:0000176//nuclear exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing	--
ENSG00000135702	0.208	0.547	0.127	0.084	0.111	0.194	4.42	9.78	1	4.56	1	2	CHST5	carbohydrate sulfotransferase 5 [Source:HGNC Symbol;Acc:HGNC:1973]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031228//intrinsic component of Golgi membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006477//protein sulfation;GO:0006790//sulfur compound metabolic process;GO:0018146//keratan sulfate biosynthetic process	--
ENSG00000135709	2.622	3.199	2.7	2.648	2.54	2.431	360	407	269	239	298	261	KIAA0513	KIAA0513 [Source:HGNC Symbol;Acc:HGNC:29058]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000135720	26.712	23.31	24.371	18.792	19.804	17.722	2315	2061	1515	1172	1460	1105	DYNC1LI2	dynein cytoplasmic 1 light intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2966]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10416;K10416;K10416	GO:0000776//kinetochore;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030286//dynein complex	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0045504//dynein heavy chain binding	GO:0000226//microtubule cytoskeleton organization;GO:0007018//microtubule-based movement;GO:0051642//centrosome localization;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000135722	1.21	0.784	2.021	1.118	0.634	3.164	36.93	26	31	25	17	58	FBXL8	F-box and leucine rich repeat protein 8 [Source:HGNC Symbol;Acc:HGNC:17875]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0051726//regulation of cell cycle	--
ENSG00000135723	2.832	3.019	3.287	5.889	3.986	2.974	224	240	192	242	242	171	FHOD1	formin homology 2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17905]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23938	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0032059//bleb;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0051015//actin filament binding	GO:0007097//nuclear migration;GO:0030866//cortical actin cytoskeleton organization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051639//actin filament network formation;GO:0051660//establishment of centrosome localization	--
ENSG00000135736	6.681	7.001	5.234	6.503	6.57	5.83	337	355	195	243	280	214	CCDC102A	coiled-coil domain containing 102A [Source:HGNC Symbol;Acc:HGNC:28097]	-	-	-	-	GO:0016459//myosin complex	-	-	--
ENSG00000135740	0.065	0.194	0.194	0.206	0.205	0.144	5	15	7	11	13	8	SLC9A5	solute carrier family 9 member A5 [Source:HGNC Symbol;Acc:HGNC:11078]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000135744	17.481	19.002	17.726	15.104	17.406	14.655	768.34	840.6	569.12	490.19	643.29	472.56	AGT	angiotensinogen [Source:HGNC Symbol;Acc:HGNC:333]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Endocrine and metabolic disease;Circulatory system;Circulatory system;Endocrine and metabolic disease;Endocrine and metabolic disease;Endocrine system;Cardiovascular disease;Endocrine system;Endocrine system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04931//Insulin resistance;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04925//Aldosterone synthesis and secretion;ko05410//Hypertrophic cardiomyopathy;ko04924//Renin secretion;ko04927//Cortisol synthesis and secretion;ko04614//Renin-angiotensin system	K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821;K09821	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0031702//type 1 angiotensin receptor binding;GO:0031703//type 2 angiotensin receptor binding	"GO:0001558//regulation of cell growth;GO:0001819//positive regulation of cytokine production;GO:0001822//kidney development;GO:0001974//blood vessel remodeling;GO:0002016//regulation of blood volume by renin-angiotensin;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0002019//regulation of renal output by angiotensin;GO:0002027//regulation of heart rate;GO:0002034//maintenance of blood vessel diameter homeostasis by renin-angiotensin;GO:0003014//renal system process;GO:0003051//angiotensin-mediated drinking behavior;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0006606//protein import into nucleus;GO:0006883//cellular sodium ion homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007199//G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007263//nitric oxide mediated signal transduction;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0007568//aging;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0008306//associative learning;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0010595//positive regulation of endothelial cell migration;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010873//positive regulation of cholesterol esterification;GO:0010951//negative regulation of endopeptidase activity;GO:0010976//positive regulation of neuron projection development;GO:0014061//regulation of norepinephrine secretion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014824//artery smooth muscle contraction;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:0016525//negative regulation of angiogenesis;GO:0019229//regulation of vasoconstriction;GO:0030308//negative regulation of cell growth;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032355//response to estradiol;GO:0032930//positive regulation of superoxide anion generation;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0034104//negative regulation of tissue remodeling;GO:0034374//low-density lipoprotein particle remodeling;GO:0035106//operant conditioning;GO:0035813//regulation of renal sodium excretion;GO:0035815//positive regulation of renal sodium excretion;GO:0042127//regulation of cell population proliferation;GO:0042310//vasoconstriction;GO:0042311//vasodilation;GO:0042981//regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043407//negative regulation of MAP kinase activity;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045777//positive regulation of blood pressure;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0048144//fibroblast proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048659//smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0051924//regulation of calcium ion transport;GO:0051969//regulation of transmission of nerve impulse;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070371//ERK1 and ERK2 cascade;GO:0070471//uterine smooth muscle contraction;GO:0071260//cellular response to mechanical stimulus;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:1901201//regulation of extracellular matrix assembly;GO:1903598//positive regulation of gap junction assembly;GO:1903779//regulation of cardiac conduction;GO:1904385//cellular response to angiotensin;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1905010//positive regulation of L-lysine import across plasma membrane;GO:1905589//positive regulation of L-arginine import across plasma membrane;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000135747	0	0.017	0	0	0	0	0	1	0	0	0	0	ZNF670-ZNF695	ZNF670-ZNF695 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49200]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000135749	3.489	4.341	4.208	4.128	4.667	2.366	422.27	422.24	270.13	228	344.24	237.89	PCNX2	pecanex 2 [Source:HGNC Symbol;Acc:HGNC:8736]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000135750	6.643	5.26	5.733	4.105	3.535	3.89	284	226	181	130	125	121	KCNK1	potassium two pore domain channel subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:6272]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0034705//potassium channel complex;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0097060//synaptic membrane;GO:1902937//inward rectifier potassium channel complex	GO:0005242//inward rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0022841//potassium ion leak channel activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0035094//response to nicotine;GO:0035725//sodium ion transmembrane transport;GO:0060075//regulation of resting membrane potential;GO:0071805//potassium ion transmembrane transport	--
ENSG00000135763	2.367	2.064	2.459	2.138	2.038	2.331	275	241	211	184	200	197	URB2	URB2 ribosome biogenesis homolog [Source:HGNC Symbol;Acc:HGNC:28967]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016235//aggresome;GO:0030496//midbody	-	GO:0042254//ribosome biogenesis;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000135766	21.629	19.39	18.193	18.603	19.69	19.41	1774.91	1548.23	1072.09	1128	1343	1150	EGLN1	egl-9 family hypoxia inducible factor 1 [Source:HGNC Symbol;Acc:HGNC:1232]	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09592;K09592;K09592	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0019899//enzyme binding;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001666//response to hypoxia;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0032364//oxygen homeostasis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045765//regulation of angiogenesis;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0071456//cellular response to hypoxia;GO:0071731//response to nitric oxide	--
ENSG00000135773	0.022	0.097	0.053	0	0.053	0.053	1	5	2	0	2	2	CAPN9	calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000135775	15.634	14.888	18.147	14.351	14.968	18.208	947.66	909.4	813.88	645.81	767.71	805.44	COG2	component of oligomeric golgi complex 2 [Source:HGNC Symbol;Acc:HGNC:6546]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0070085//glycosylation"	--
ENSG00000135776	5.533	5.182	5.905	5.198	5.457	7.073	444	418	350	309	370	413	ABCB10	ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05657	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032592//integral component of mitochondrial membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0140359//ABC-type transporter activity	GO:0006783//heme biosynthetic process;GO:0006839//mitochondrial transport;GO:0034514//mitochondrial unfolded protein response;GO:0045648//positive regulation of erythrocyte differentiation;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048821//erythrocyte development;GO:0055085//transmembrane transport;GO:0070455//positive regulation of heme biosynthetic process	--
ENSG00000135778	10.168	10.413	10.518	10.193	8.716	9.154	1215.73	1194.76	906.87	755	811.76	698.11	NTPCR	"nucleoside-triphosphatase, cancer-related [Source:HGNC Symbol;Acc:HGNC:28204]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K06928;K06928;K06928	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017111//nucleoside-triphosphatase activity	-	--
ENSG00000135801	3.337	3.186	4.257	2.883	2.783	3.079	234	223	177	150	160	160	TAF5L	TATA-box binding protein associated factor 5 like [Source:HGNC Symbol;Acc:HGNC:17304]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03130	GO:0000123//histone acetyltransferase complex;GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0033276//transcription factor TFTC complex;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006282//regulation of DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1904672//regulation of somatic stem cell population maintenance"	--
ENSG00000135821	269.527	279.04	308.365	303.925	308.199	323.657	23272	24302	19631	19390	22646	20338	GLUL	glutamate-ammonia ligase [Source:HGNC Symbol;Acc:HGNC:4341]	Metabolism;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cell growth and death;Nervous system;Nervous system;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Amino acid metabolism;Energy metabolism	"ko01100//Metabolic pathways;ko04217//Necroptosis;ko04724//Glutamatergic synapse;ko04727//GABAergic synapse;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00220//Arginine biosynthesis;ko00910//Nitrogen metabolism"	K01915;K01915;K01915;K01915;K01915;K01915;K01915;K01915;K01915	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0043209//myelin sheath;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus;GO:0044297//cell body;GO:0070062//extracellular exosome;GO:0097386//glial cell projection	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004356//glutamate-ammonia ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016595//glutamate binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0045503//dynein light chain binding;GO:0046872//metal ion binding	"GO:0001525//angiogenesis;GO:0006536//glutamate metabolic process;GO:0006538//glutamate catabolic process;GO:0006542//glutamine biosynthetic process;GO:0006807//nitrogen compound metabolic process;GO:0008283//cell population proliferation;GO:0009267//cellular response to starvation;GO:0009749//response to glucose;GO:0010594//regulation of endothelial cell migration;GO:0018345//protein palmitoylation;GO:0019676//ammonia assimilation cycle;GO:0019752//carboxylic acid metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0042254//ribosome biogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:1903670//regulation of sprouting angiogenesis;GO:1904749//regulation of protein localization to nucleolus"	--
ENSG00000135823	9.211	8.815	8.889	7.97	8.174	9.795	919	884	655	589	689	711	STX6	syntaxin 6 [Source:HGNC Symbol;Acc:HGNC:11441]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08498	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0030285//integral component of synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0032588//trans-Golgi network membrane;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0007032//endosome organization;GO:0015031//protein transport;GO:0016189//synaptic vesicle to endosome fusion;GO:0016192//vesicle-mediated transport;GO:0032456//endocytic recycling;GO:0032880//regulation of protein localization;GO:0042147//retrograde transport, endosome to Golgi;GO:0048193//Golgi vesicle transport;GO:0048278//vesicle docking;GO:0090161//Golgi ribbon formation"	--
ENSG00000135824	0.123	0.043	0.023	0.128	0	0.012	2	5	2	11	0	1	RGS8	regulator of G protein signaling 8 [Source:HGNC Symbol;Acc:HGNC:16810]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0060159//regulation of dopamine receptor signaling pathway	--
ENSG00000135828	3.808	3.094	3.375	3.643	3.662	3.6	334	273	219	237	271	230	RNASEL	ribonuclease L [Source:HGNC Symbol;Acc:HGNC:10050]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral	ko05168//Herpes simplex virus 1 infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05160//Hepatitis C	K01165;K01165;K01165;K01165	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016363//nuclear matrix	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004540//ribonuclease activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0019843//rRNA binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0046872//metal ion binding	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0043488//regulation of mRNA stability;GO:0045071//negative regulation of viral genome replication;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0051607//defense response to virus;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000135829	46.956	42.168	43.426	37.186	39.233	41.558	4376	3950	2989	2567	3089	2818	DHX9	DExH-box helicase 9 [Source:HGNC Symbol;Acc:HGNC:2750]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005726//perichromatin fibrils;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005844//polysome;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016442//RISC complex;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042788//polysomal ribosome;GO:0070578//RISC-loading complex;GO:0070937//CRD-mediated mRNA stability complex;GO:0097165//nuclear stress granule;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0001069//regulatory region RNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003688//DNA replication origin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017111//nucleoside-triphosphatase activity;GO:0031490//chromatin DNA binding;GO:0033679//3'-5' DNA/RNA helicase activity;GO:0034458//3'-5' RNA helicase activity;GO:0035197//siRNA binding;GO:0035613//RNA stem-loop binding;GO:0043138//3'-5' DNA helicase activity;GO:0045142//triplex DNA binding;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061676//importin-alpha family protein binding;GO:0070063//RNA polymerase binding;GO:1905172//RISC complex binding;GO:1905538//polysome binding;GO:1990518//single-stranded 3'-5' DNA helicase activity;GO:1990825//sequence-specific mRNA binding;GO:1990841//promoter-specific chromatin binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0002376//immune system process;GO:0006260//DNA replication;GO:0006353//DNA-templated transcription, termination;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0006954//inflammatory response;GO:0008380//RNA splicing;GO:0010501//RNA secondary structure unwinding;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0032508//DNA duplex unwinding;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032741//positive regulation of interleukin-18 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034622//cellular protein-containing complex assembly;GO:0039695//DNA-templated viral transcription;GO:0044806//G-quadruplex DNA unwinding;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045739//positive regulation of DNA repair;GO:0045740//positive regulation of DNA replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046833//positive regulation of RNA export from nucleus;GO:0048146//positive regulation of fibroblast proliferation;GO:0048511//rhythmic process;GO:0050434//positive regulation of viral transcription;GO:0050684//regulation of mRNA processing;GO:0050691//regulation of defense response to virus by host;GO:0050729//positive regulation of inflammatory response;GO:0051028//mRNA transport;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060760//positive regulation of response to cytokine stimulus;GO:0070269//pyroptosis;GO:0070922//small RNA loading onto RISC;GO:0070934//CRD-mediated mRNA stabilization;GO:0071356//cellular response to tumor necrosis factor;GO:0071360//cellular response to exogenous dsRNA;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1903608//protein localization to cytoplasmic stress granule;GO:1904973//positive regulation of viral translation;GO:1905698//positive regulation of polysome binding;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:2000637//positive regulation of gene silencing by miRNA;GO:2000765//regulation of cytoplasmic translation;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000135835	1.911	1.609	2.079	3.107	4.634	2.957	142	155	126	190	236	177	KIAA1614	KIAA1614 [Source:HGNC Symbol;Acc:HGNC:29327]	-	-	-	-	GO:0005634//nucleus;GO:0005938//cell cortex;GO:0016324//apical plasma membrane	GO:0005080//protein kinase C binding;GO:0005515//protein binding	GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0060341//regulation of cellular localization	--
ENSG00000135837	4.939	2.027	1.455	1.095	1.157	1.588	618	388	229	152	224	232	CEP350	centrosomal protein 350 [Source:HGNC Symbol;Acc:HGNC:24238]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0034453//microtubule anchoring;GO:0071539//protein localization to centrosome;GO:1905515//non-motile cilium assembly	--
ENSG00000135838	0.581	0.672	0.496	0.571	0.626	0.712	21	35	18	22	25	27	NPL	N-acetylneuraminate pyruvate lyase [Source:HGNC Symbol;Acc:HGNC:16781]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01639;K01639	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008747//N-acetylneuraminate lyase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding	GO:0005975//carbohydrate metabolic process;GO:0019262//N-acetylneuraminate catabolic process	--
ENSG00000135842	8.859	7.225	7.889	9.247	8.762	8.74	1265	1037	832	935	1057	908	NIBAN1	niban apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16784]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006417//regulation of translation;GO:0034976//response to endoplasmic reticulum stress;GO:0045727//positive regulation of translation	--
ENSG00000135845	13.355	11.299	12.194	11.578	11.458	12.587	404	343	274	261	293	278	PIGC	phosphatidylinositol glycan anchor biosynthesis class C [Source:HGNC Symbol;Acc:HGNC:8960]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03859;K03859	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0005515//protein binding	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000135862	44.806	45.116	42.827	36.963	42.354	39.277	7369	7458	5202	4503	5885	4700	LAMC1	laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05020//Prion disease;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K05635;K05635;K05635;K05635;K05635;K05635;K05635;K05635;K05635	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005606//laminin-1 complex;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0043259//laminin-10 complex;GO:0043260//laminin-11 complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005201//extracellular matrix structural constituent;GO:0030023//extracellular matrix constituent conferring elasticity	GO:0007155//cell adhesion;GO:0007492//endoderm development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0022617//extracellular matrix disassembly;GO:0031581//hemidesmosome assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035633//maintenance of blood-brain barrier;GO:0045785//positive regulation of cell adhesion;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051149//positive regulation of muscle cell differentiation;GO:0065003//protein-containing complex assembly;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000135870	2.623	2.507	2.179	1.499	2.031	2.141	501	495	357	228	346	323	RC3H1	ring finger and CCCH-type domains 1 [Source:HGNC Symbol;Acc:HGNC:29434]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0035198//miRNA binding;GO:0035613//RNA stem-loop binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:1905762//CCR4-NOT complex binding	"GO:0000209//protein polyubiquitination;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0001782//B cell homeostasis;GO:0002634//regulation of germinal center formation;GO:0002635//negative regulation of germinal center formation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010468//regulation of gene expression;GO:0010608//posttranscriptional regulation of gene expression;GO:0016567//protein ubiquitination;GO:0030889//negative regulation of B cell proliferation;GO:0033962//P-body assembly;GO:0042098//T cell proliferation;GO:0042129//regulation of T cell proliferation;GO:0043029//T cell homeostasis;GO:0043488//regulation of mRNA stability;GO:0045623//negative regulation of T-helper cell differentiation;GO:0046007//negative regulation of activated T cell proliferation;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0050852//T cell receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050863//regulation of T cell activation;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0061470//T follicular helper cell differentiation;GO:0071347//cellular response to interleukin-1;GO:1900151//regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000628//regulation of miRNA metabolic process"	--
ENSG00000135898	0.025	0.025	0.068	0.142	0.015	0.072	2	2	4	6	1	1	GPR55	G protein-coupled receptor 55 [Source:HGNC Symbol;Acc:HGNC:4511]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004949//cannabinoid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0038171//cannabinoid signaling pathway;GO:0045453//bone resorption;GO:0045671//negative regulation of osteoclast differentiation;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000135899	2.593	3.822	3.274	2.162	2.455	2.521	135	185	111	76	109	96	SP110	SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	SAND
ENSG00000135900	14.929	17.408	16.348	15.144	17.096	18.831	523	613	423	393	506	480	MRPL44	mitochondrial ribosomal protein L44 [Source:HGNC Symbol;Acc:HGNC:16650]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0016604//nuclear body	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003735//structural constituent of ribosome;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004525//ribonuclease III activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0006396//RNA processing;GO:0016075//rRNA catabolic process;GO:0032543//mitochondrial translation;GO:0070125//mitochondrial translational elongation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000135902	0	0	0.114	0	0	0	0	0	2	0	0	0	CHRND	cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04816	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0015276//ligand-gated ion channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0003009//skeletal muscle contraction;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0048630//skeletal muscle tissue growth;GO:0050877//nervous system process;GO:0050881//musculoskeletal movement;GO:0050905//neuromuscular process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0095500//acetylcholine receptor signaling pathway	--
ENSG00000135903	0.046	0.2	0.049	0.065	0.051	0.042	3	4	1	3	3	2	PAX3	paired box 3 [Source:HGNC Symbol;Acc:HGNC:8617]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09381	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0007605//sensory perception of sound;GO:0009887//animal organ morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	PAX
ENSG00000135905	0.304	0.185	0.027	0.296	0.256	0.371	23	16	3	14	19	8	DOCK10	dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0001782//B cell homeostasis;GO:0002315//marginal zone B cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0030334//regulation of cell migration;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0060997//dendritic spine morphogenesis	--
ENSG00000135912	166.231	176.213	152.878	144.225	160.554	125.19	15738	16442	10535	10124	12826	8407	TTLL4	tubulin tyrosine ligase like 4 [Source:HGNC Symbol;Acc:HGNC:28976]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097731//9+0 non-motile cilium	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070739//protein-glutamic acid ligase activity;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation;GO:0018200//peptidyl-glutamic acid modification;GO:0120222//regulation of blastocyst development	--
ENSG00000135913	2.974	2.352	2.088	1.768	1.823	1.774	432	359	248	184	248	204	USP37	ubiquitin specific peptidase 37 [Source:HGNC Symbol;Acc:HGNC:20063]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006275//regulation of DNA replication;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0051301//cell division;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000135914	2.866	2.277	0.963	1.26	0.973	1.74	129	103	32	42	37	57	HTR2B	5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system;Cellular community - eukaryotes	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04726//Serotonergic synapse;ko04750//Inflammatory mediator regulation of TRP channels;ko04540//Gap junction	K04157;K04157;K04157;K04157;K04157	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098666//G protein-coupled serotonin receptor complex	GO:0001587//Gq/11-coupled serotonin receptor activity;GO:0001965//G-protein alpha-subunit binding;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0001755//neural crest cell migration;GO:0001819//positive regulation of cytokine production;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002031//G protein-coupled receptor internalization;GO:0003007//heart morphogenesis;GO:0003300//cardiac muscle hypertrophy;GO:0006874//cellular calcium ion homeostasis;GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007507//heart development;GO:0007610//behavior;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010507//negative regulation of autophagy;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0014033//neural crest cell differentiation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014827//intestine smooth muscle contraction;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0042310//vasoconstriction;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0048598//embryonic morphogenesis;GO:0050795//regulation of behavior;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051781//positive regulation of cell division;GO:0060548//negative regulation of cell death;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070528//protein kinase C signaling;GO:0071502//cellular response to temperature stimulus;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000135916	251.618	257.296	304.671	316.061	320.923	341.98	9829	9996	8704	9246	10364	9562	ITM2C	integral membrane protein 2C [Source:HGNC Symbol;Acc:HGNC:6175]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0010977//negative regulation of neuron projection development;GO:0030182//neuron differentiation;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000135917	0.754	0.295	0.167	0.221	0.503	0.54	21	20	7	9	15	11	SLC19A3	solute carrier family 19 member 3 [Source:HGNC Symbol;Acc:HGNC:16266]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14610	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015234//thiamine transmembrane transporter activity;GO:0090482//vitamin transmembrane transporter activity	GO:0015888//thiamine transport;GO:0035461//vitamin transmembrane transport;GO:0042723//thiamine-containing compound metabolic process;GO:0051180//vitamin transport;GO:0055085//transmembrane transport;GO:0071934//thiamine transmembrane transport	--
ENSG00000135919	8.64	10.709	6.127	4.535	4.875	5.057	399	464	209	142	188	143	SERPINE2	serpin family E member 2 [Source:HGNC Symbol;Acc:HGNC:8951]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0031091//platelet alpha granule;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031594//neuromuscular junction;GO:0062023//collagen-containing extracellular matrix;GO:1903561//extracellular vesicle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity	"GO:0007399//nervous system development;GO:0007596//blood coagulation;GO:0008285//negative regulation of cell population proliferation;GO:0009611//response to wounding;GO:0010466//negative regulation of peptidase activity;GO:0010544//negative regulation of platelet activation;GO:0010757//negative regulation of plasminogen activation;GO:0010766//negative regulation of sodium ion transport;GO:0010951//negative regulation of endopeptidase activity;GO:0010955//negative regulation of protein processing;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0021683//cerebellar granular layer morphogenesis;GO:0030154//cell differentiation;GO:0030195//negative regulation of blood coagulation;GO:0030308//negative regulation of cell growth;GO:0030334//regulation of cell migration;GO:0032940//secretion by cell;GO:0033363//secretory granule organization;GO:0042177//negative regulation of protein catabolic process;GO:0042628//mating plug formation;GO:0045861//negative regulation of proteolysis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048505//regulation of timing of cell differentiation;GO:0048711//positive regulation of astrocyte differentiation;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060291//long-term synaptic potentiation;GO:0060384//innervation;GO:0061108//seminal vesicle epithelium development;GO:0090331//negative regulation of platelet aggregation"	--
ENSG00000135924	38.509	36.753	35.314	39.205	40.262	36.412	1446	1301	1046	1118	1204	1013	DNAJB2	DnaJ heat shock protein family (Hsp40) member B2 [Source:HGNC Symbol;Acc:HGNC:5228]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09508	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016234//inclusion body;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031965//nuclear membrane	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0070628//proteasome binding;GO:0140036//ubiquitin-dependent protein binding	GO:0006986//response to unfolded protein;GO:0008285//negative regulation of cell population proliferation;GO:0030308//negative regulation of cell growth;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031396//regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032781//positive regulation of ATPase activity;GO:0032880//regulation of protein localization;GO:0042026//protein refolding;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0061077//chaperone-mediated protein folding;GO:0070050//neuron cellular homeostasis;GO:0090084//negative regulation of inclusion body assembly;GO:0090086//negative regulation of protein deubiquitination;GO:1903644//regulation of chaperone-mediated protein folding	--
ENSG00000135925	0.094	0.094	0.476	0.475	0.583	0.387	4	2	15	15	21	12	WNT10A	Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity	GO:0001942//hair follicle development;GO:0007275//multicellular organism development;GO:0010628//positive regulation of gene expression;GO:0014033//neural crest cell differentiation;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0031069//hair follicle morphogenesis;GO:0042476//odontogenesis;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0043586//tongue development;GO:0043588//skin development;GO:0045165//cell fate commitment;GO:0048730//epidermis morphogenesis;GO:0048733//sebaceous gland development;GO:0060070//canonical Wnt signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000135926	44.967	46.499	46.571	44.41	44.159	40.223	1688	1722	1253	1209	1370	1085	TMBIM1	transmembrane BAX inhibitor motif containing 1 [Source:HGNC Symbol;Acc:HGNC:23410]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005123//death receptor binding;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902045//negative regulation of Fas signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000504//positive regulation of blood vessel remodeling;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000135929	146.764	161.34	175.1	179.27	175.418	148.379	5747	6371	5056	5182	5786	4227	CYP27A1	cytochrome P450 family 27 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2605]	Metabolism;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Digestive system;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism;ko00120//Primary bile acid biosynthesis	K00488;K00488;K00488;K00488	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0031073//cholesterol 26-hydroxylase activity;GO:0046872//metal ion binding;GO:0047103//3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity;GO:0047748//cholestanetetraol 26-dehydrogenase activity;GO:0047749//cholestanetriol 26-monooxygenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0006707//cholesterol catabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0036378//calcitriol biosynthetic process from calciol	--
ENSG00000135930	37.817	39.17	38.424	34.378	34.946	36.022	1432	1333	992	890	1022	951	EIF4E2	eukaryotic translation initiation factor 4E family member 2 [Source:HGNC Symbol;Acc:HGNC:3293]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Endocrine system;Signal transduction;Aging;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko04150//mTOR signaling pathway;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K03259;K03259;K03259;K03259;K03259;K03259	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0016281//eukaryotic translation initiation factor 4F complex	"GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0031625//ubiquitin protein ligase binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0031047//gene silencing by RNA;GO:1905618//positive regulation of miRNA mediated inhibition of translation	--
ENSG00000135931	28.106	30.869	27.337	21.959	21.347	21.369	2346	2448	1714	1329	1596	1428	ARMC9	armadillo repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:20730]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0097542//ciliary tip	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0045880//positive regulation of smoothened signaling pathway;GO:0060271//cilium assembly	--
ENSG00000135932	21.279	17.519	20.577	17.697	16.572	20.808	1690	1394	1207	1025	1112	1194	CAB39	calcium binding protein 39 [Source:HGNC Symbol;Acc:HGNC:20292]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04150//mTOR signaling pathway;ko04152//AMPK signaling pathway	K08272;K08272	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030018//Z disc;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1902554//serine/threonine protein kinase complex;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity;GO:0043539//protein serine/threonine kinase activator activity	GO:0007165//signal transduction;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0014823//response to activity;GO:0018105//peptidyl-serine phosphorylation;GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0071476//cellular hypotonic response;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097066//response to thyroid hormone;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901380//negative regulation of potassium ion transmembrane transport	--
ENSG00000135940	85.663	83.348	94.699	98.29	82.289	107.841	1226	1199	1001	1042	995	1123	COX5B	cytochrome c oxidase subunit 5B [Source:HGNC Symbol;Acc:HGNC:2269]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265;K02265	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000135945	4.446	4.132	3.553	2.7	3.575	3.794	434.68	406.71	257.5	196.05	260.12	269.57	REV1	REV1 DNA directed polymerase [Source:HGNC Symbol;Acc:HGNC:14060]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K03515	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0017125//deoxycytidyl transferase activity;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0042276//error-prone translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0071897//DNA biosynthetic process	--
ENSG00000135951	0.281	0.531	0.325	0.217	0.242	0.313	18	32	16	10	13	12	TSGA10	testis specific 10 [Source:HGNC Symbol;Acc:HGNC:14927]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0031514//motile cilium	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007283//spermatogenesis	--
ENSG00000135953	5.053	3.191	4.478	5.221	3.627	4.197	369	310	225	223	286	255	MFSD9	major facilitator superfamily domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28158]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000135956	23.166	25.53	25.297	25.042	25.416	26.467	1883	2008	1501	1532	1714	1525	TMEM127	transmembrane protein 127 [Source:HGNC Symbol;Acc:HGNC:26038]	-	-	-	-	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0031267//small GTPase binding	GO:0007032//endosome organization;GO:0008285//negative regulation of cell population proliferation;GO:0032006//regulation of TOR signaling;GO:0032007//negative regulation of TOR signaling	--
ENSG00000135960	0	0.035	0.096	0.096	0.042	0.065	0	3	6	6	3	4	EDAR	ectodysplasin A receptor [Source:HGNC Symbol;Acc:HGNC:2895]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway	K05162;K05162	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001942//hair follicle development;GO:0006915//apoptotic process;GO:0008544//epidermis development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043473//pigmentation;GO:0046330//positive regulation of JNK cascade;GO:0060662//salivary gland cavitation;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000135966	9.583	9.511	10.501	8.895	9.056	10.194	931	929.02	750.67	637	743	750	TGFBRAP1	transforming growth factor beta receptor associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16836]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0033263//CORVET complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0046332//SMAD binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly"	--
ENSG00000135968	4.008	1.86	1.773	1.458	2.198	1.865	423.28	266.1	175	131	201.34	182.56	GCC2	GRIP and coiled-coil domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23218]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20282	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	"GO:0006622//protein targeting to lysosome;GO:0015031//protein transport;GO:0031023//microtubule organizing center organization;GO:0034067//protein localization to Golgi apparatus;GO:0034453//microtubule anchoring;GO:0034499//late endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0070861//regulation of protein exit from endoplasmic reticulum;GO:0071955//recycling endosome to Golgi transport;GO:0090161//Golgi ribbon formation"	--
ENSG00000135972	10.399	10.651	9.371	9.298	9	9.372	305	314	203	202	223	200	MRPS9	mitochondrial ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:14501]	Genetic Information Processing	Translation	ko03010//Ribosome	K02996	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000135973	0.028	0.028	0	0	0.033	0	1	1	0	0	1	0	GPR45	G protein-coupled receptor 45 [Source:HGNC Symbol;Acc:HGNC:4503]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000135974	5.662	4.179	5.019	3.808	4.366	5.28	330	280	267	180	230	253	C2orf49	chromosome 2 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28772]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0072669//tRNA-splicing ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0048598//embryonic morphogenesis	--
ENSG00000135976	0.273	0.146	0.193	0.091	0.086	0.085	34.14	19.86	19.36	8.44	10.83	8.38	ANKRD36	ankyrin repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:24079]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000135999	5.877	4.525	5.227	3.743	4.037	4.604	416	342	250	195	259	243	EPC2	enhancer of polycomb homolog 2 [Source:HGNC Symbol;Acc:HGNC:24543]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0032777//Piccolo NuA4 histone acetyltransferase complex;GO:0035267//NuA4 histone acetyltransferase complex	-	"GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0016573//histone acetylation;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000136002	9.422	9.839	8.923	7.924	7.473	6.531	510	595	371	314	391	299	ARHGEF4	Rho guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:684]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05769	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0030032//lamellipodium assembly;GO:0035556//intracellular signal transduction;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000136003	43.887	48.94	42.177	42.574	38.966	45.447	900	1010	640	645	681	680	ISCU	iron-sulfur cluster assembly enzyme [Source:HGNC Symbol;Acc:HGNC:29882]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1990229//iron-sulfur cluster assembly complex	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0060090//molecular adaptor activity"	"GO:0006879//cellular iron ion homeostasis;GO:0016226//iron-sulfur cluster assembly;GO:1902958//positive regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1904234//positive regulation of aconitate hydratase activity;GO:1904439//negative regulation of iron ion import across plasma membrane"	--
ENSG00000136010	0.87	0.639	0.615	0.273	0.515	0.937	134	99	70	34	67	106	ALDH1L2	aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K00289;K00289	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0016155//formyltetrahydrofolate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016742//hydroxymethyl-, formyl- and related transferase activity"	GO:0006635//fatty acid beta-oxidation;GO:0006730//one-carbon metabolic process;GO:0006740//NADPH regeneration;GO:0009058//biosynthetic process;GO:0009258//10-formyltetrahydrofolate catabolic process;GO:0046655//folic acid metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000136011	0.323	0.006	0.196	0.333	0.028	0	5	1	2	3	4	0	STAB2	stabilin 2 [Source:HGNC Symbol;Acc:HGNC:18629]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005044//scavenger receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0015035//protein-disulfide reductase activity;GO:0030169//low-density lipoprotein particle binding	GO:0001525//angiogenesis;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007155//cell adhesion;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000136014	2.034	1.499	1.158	1.147	0.865	0.959	140	107	52	38	58	58	USP44	ubiquitin specific peptidase 44 [Source:HGNC Symbol;Acc:HGNC:20064]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0016579//protein deubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051301//cell division;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000136021	18.722	17.162	14.328	11.931	13.752	16.454	1758	1529	968	825	1050	1136	SCYL2	SCY1 like pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:19286]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle	GO:0004672//protein kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0002092//positive regulation of receptor internalization;GO:0006468//protein phosphorylation;GO:0007420//brain development;GO:0008333//endosome to lysosome transport;GO:0021860//pyramidal neuron development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:2000370//positive regulation of clathrin-dependent endocytosis	--
ENSG00000136026	59.642	59.307	57.371	64.315	61.215	55.879	3861	3859	2743	3084	3348	2632	CKAP4	cytoskeleton associated protein 4 [Source:HGNC Symbol;Acc:HGNC:16991]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13999	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0042599//lamellar body;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000136040	0.635	0.861	1	0.644	1.171	1.022	82	71	54	58	72	77	PLXNC1	plexin C1 [Source:HGNC Symbol;Acc:HGNC:9106]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06572	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017154//semaphorin receptor activity	GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0030334//regulation of cell migration;GO:0043087//regulation of GTPase activity;GO:0050772//positive regulation of axonogenesis;GO:0071526//semaphorin-plexin signaling pathway;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000136044	21.262	22.39	22.269	19.027	19.23	23.131	1335	1354	1024	885	1044	1087	APPL2	"adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]"	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0032009//early phagosome;GO:0032587//ruffle membrane;GO:0036186//early phagosome membrane;GO:0042995//cell projection;GO:0044354//macropinosome;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding	"GO:0002024//diet induced thermogenesis;GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009631//cold acclimation;GO:0010762//regulation of fibroblast migration;GO:0023052//signaling;GO:0033211//adiponectin-activated signaling pathway;GO:0034143//regulation of toll-like receptor 4 signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0042593//glucose homeostasis;GO:0045088//regulation of innate immune response;GO:0046322//negative regulation of fatty acid oxidation;GO:0046325//negative regulation of glucose import;GO:0050768//negative regulation of neurogenesis;GO:0051289//protein homotetramerization;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900077//negative regulation of cellular response to insulin stimulus;GO:1905303//positive regulation of macropinocytosis;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000178//negative regulation of neural precursor cell proliferation"	--
ENSG00000136045	15.273	14.002	14.933	12.666	11.9	16.239	656	678	536	450	466	496	PWP1	"PWP1 homolog, endonuclein [Source:HGNC Symbol;Acc:HGNC:17015]"	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005794//Golgi apparatus	GO:0005515//protein binding;GO:1990889//H4K20me3 modified histone binding	"GO:0006351//transcription, DNA-templated;GO:0006364//rRNA processing;GO:0033140//negative regulation of peptidyl-serine phosphorylation of STAT protein;GO:0034773//histone H4-K20 trimethylation;GO:0042254//ribosome biogenesis;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:2000738//positive regulation of stem cell differentiation"	--
ENSG00000136048	8.129	7.621	10.173	7.384	5.898	9.793	535	521	511	368	335	480	DRAM1	DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0010506//regulation of autophagy	--
ENSG00000136051	8.452	4.763	6.975	4.978	4.622	6.184	876	519	443	358	469	511	WASHC4	WASH complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:29174]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18465	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0031083//BLOC-1 complex;GO:0031901//early endosome membrane;GO:0071203//WASH complex	-	GO:0007032//endosome organization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0140591//nuclear envelope budding	--
ENSG00000136052	14.837	11.779	9.27	10.118	9.004	10.979	918	699	498	440	494	555	SLC41A2	solute carrier family 41 member 2 [Source:HGNC Symbol;Acc:HGNC:31045]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0030001//metal ion transport;GO:0098655//cation transmembrane transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000136059	15.474	17.843	14.009	15.029	12.009	10.844	625	728	416	438	421	324	VILL	villin like [Source:HGNC Symbol;Acc:HGNC:30906]	-	-	-	-	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton	"GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0051015//actin filament binding"	GO:0007010//cytoskeleton organization;GO:0008154//actin polymerization or depolymerization;GO:0045010//actin nucleation;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping	--
ENSG00000136068	28.348	31.865	30.104	26.988	26.489	25.981	5467	5809	4267	3509	4265	3269	FLNB	filamin B [Source:HGNC Symbol;Acc:HGNC:3755]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Signal transduction;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko05132//Salmonella infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion	K04437;K04437;K04437;K04437	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0003334//keratinocyte development;GO:0003382//epithelial cell morphogenesis;GO:0007165//signal transduction;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0071346//cellular response to interferon-gamma	--
ENSG00000136098	1.806	1.527	2.039	1.302	1.486	1.699	81	62	52	39	56	49	NEK3	NIMA related kinase 3 [Source:HGNC Symbol;Acc:HGNC:7746]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0030010//establishment of cell polarity;GO:0048812//neuron projection morphogenesis;GO:0051301//cell division;GO:0090043//regulation of tubulin deacetylation	--
ENSG00000136099	0.161	0.157	0.176	0.051	0.199	0.322	17	14	10	4	15	21	PCDH8	protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0005509//calcium ion binding	GO:0001756//somitogenesis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0016331//morphogenesis of embryonic epithelium;GO:0099179//regulation of synaptic membrane adhesion	--
ENSG00000136100	7.861	6.331	6.859	6.172	6.538	6.319	722	585	466	421	507	422	VPS36	vacuolar protein sorting 36 homolog [Source:HGNC Symbol;Acc:HGNC:20312]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12190	GO:0000814//ESCRT II complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043130//ubiquitin binding	GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0090148//membrane fission	--
ENSG00000136104	8.628	7.928	8.084	6.032	8.48	6.118	284	256	189	143	232	138	RNASEH2B	ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K10744	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032299//ribonuclease H2 complex	-	GO:0001701//in utero embryonic development;GO:0006298//mismatch repair;GO:0006401//RNA catabolic process;GO:0009259//ribonucleotide metabolic process;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010629//negative regulation of gene expression;GO:0048146//positive regulation of fibroblast proliferation;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000136108	10.142	9.911	8.466	5.936	7.186	7.4	671	616	430	283	356	376	CKAP2	cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0072686//mitotic spindle	-	GO:0000281//mitotic cytokinesis;GO:0006915//apoptotic process;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000136110	7.702	7.877	7.168	8.283	6.897	7.768	219	222	143	160	163	150	CNMD	chondromodulin [Source:HGNC Symbol;Acc:HGNC:17005]	-	-	-	-	GO:0005576//extracellular region;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006029//proteoglycan metabolic process;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0051216//cartilage development	--
ENSG00000136111	1.283	1.286	1.167	1.195	1.648	0.989	165	142	102	115	137	93	TBC1D4	TBC1 domain family member 4 [Source:HGNC Symbol;Acc:HGNC:19165]	Human Diseases;Organismal Systems;Human Diseases	Cardiovascular disease;Endocrine system;Endocrine and metabolic disease	ko05415//Diabetic cardiomyopathy;ko04919//Thyroid hormone signaling pathway;ko04931//Insulin resistance	K17902;K17902;K17902	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031982//vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0016192//vesicle-mediated transport;GO:0031339//negative regulation of vesicle fusion;GO:0032869//cellular response to insulin stimulus;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000136114	0.175	0.159	0.302	0.172	0.168	0.043	11	10	14	8	9	2	THSD1	thrombospondin type 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17754]	-	-	-	-	GO:0005576//extracellular region;GO:0005768//endosome;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0071944//cell periphery	GO:0005515//protein binding;GO:0050840//extracellular matrix binding	GO:0048041//focal adhesion assembly	--
ENSG00000136122	1.188	0.739	1.072	0.675	0.755	1.473	67.22	36.73	41.94	15	36.54	44.81	BORA	BORA aurora kinase A activator [Source:HGNC Symbol;Acc:HGNC:24724]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0072687//meiotic spindle	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0032147//activation of protein kinase activity;GO:0032880//regulation of protein localization;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization	--
ENSG00000136141	3.895	3.336	3.089	2.388	3.077	3.31	381	327	221	173	254	235	LRCH1	leucine rich repeats and calponin homology domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20309]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0034260//negative regulation of GTPase activity;GO:1990869//cellular response to chemokine;GO:2000405//negative regulation of T cell migration	--
ENSG00000136143	21.069	19.192	20.055	17.252	18.232	18.893	758	714.04	492	433	481	541	SUCLA2	succinate-CoA ligase ADP-forming subunit beta [Source:HGNC Symbol;Acc:HGNC:11448]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00640//Propanoate metabolism;ko00020//Citrate cycle (TCA cycle)	K01900;K01900;K01900;K01900	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0009361//succinate-CoA ligase complex (ADP-forming);GO:0042709//succinate-CoA ligase complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0004776//succinate-CoA ligase (GDP-forming) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006099//tricarboxylic acid cycle;GO:0006104//succinyl-CoA metabolic process;GO:0006105//succinate metabolic process;GO:0006781//succinyl-CoA pathway;GO:1901289//succinyl-CoA catabolic process	--
ENSG00000136144	12.538	11.517	11.869	11.122	9.898	12.664	1031	962	726	676	694	766	RCBTB1	RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006325//chromatin organization;GO:0007049//cell cycle	--
ENSG00000136146	13.182	10.738	10.637	11.112	10.621	12.14	391	319	255	274	259	284	MED4	mediator complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:17903]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15146	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000136147	6.134	5.419	7.019	4.995	4.328	5.189	172	152	136	102	102	100	PHF11	PHD finger protein 11 [Source:HGNC Symbol;Acc:HGNC:17024]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000136152	6.721	6.876	7.452	4.558	5.199	5.31	635	653	520	319	404	365	COG3	component of oligomeric golgi complex 3 [Source:HGNC Symbol;Acc:HGNC:18619]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032580//Golgi cisterna membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006486//protein glycosylation;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0033365//protein localization to organelle;GO:0050821//protein stabilization;GO:0070085//glycosylation"	--
ENSG00000136153	3.285	2.967	2.467	1.671	0.649	0.936	197	197	113	37	47	32	LMO7	LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:6646]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K06084	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042805//actinin binding;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination;GO:0023051//regulation of signaling;GO:0030155//regulation of cell adhesion;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000136155	0	0	0	0	0	0	0	0	0	0	0	0	SCEL	sciellin [Source:HGNC Symbol;Acc:HGNC:10573]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008544//epidermis development;GO:0009612//response to mechanical stimulus;GO:0009792//embryo development ending in birth or egg hatching;GO:0030216//keratinocyte differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000136156	593.96	572.98	610.333	557.996	522.943	591.413	16752	16181	12726	11512	12375	12043	ITM2B	integral membrane protein 2B [Source:HGNC Symbol;Acc:HGNC:6174]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0007399//nervous system development;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process	--
ENSG00000136158	8.519	8.509	12.64	12.191	13.041	13.309	405	408	443	431	524	461	SPRY2	sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17383	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:1990752//microtubule end	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0043539//protein serine/threonine kinase activator activity	GO:0000132//establishment of mitotic spindle orientation;GO:0007275//multicellular organism development;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell population proliferation;GO:0009966//regulation of signal transduction;GO:0010628//positive regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031345//negative regulation of cell projection organization;GO:0031397//negative regulation of protein ubiquitination;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034260//negative regulation of GTPase activity;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042472//inner ear morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043407//negative regulation of MAP kinase activity;GO:0045165//cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048513//animal organ development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0060425//lung morphogenesis;GO:0060437//lung growth;GO:0060449//bud elongation involved in lung branching;GO:0060541//respiratory system development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1902747//negative regulation of lens fiber cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000136159	6.468	5.889	6.568	5.844	5.653	6.223	260	237.96	195	174	192	182	NUDT15	nudix hydrolase 15 [Source:HGNC Symbol;Acc:HGNC:23063]	-	-	-	-	GO:0005829//cytosol	"GO:0004551//nucleotide diphosphatase activity;GO:0005515//protein binding;GO:0008413//8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0035539//8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity;GO:0036218//dTTP diphosphatase activity;GO:0044715//8-oxo-dGDP phosphatase activity;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity"	GO:0000278//mitotic cell cycle;GO:0000302//response to reactive oxygen species;GO:0006195//purine nucleotide catabolic process;GO:0006203//dGTP catabolic process;GO:0009217//purine deoxyribonucleoside triphosphate catabolic process;GO:0042178//xenobiotic catabolic process;GO:0042262//DNA protection;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0061136//regulation of proteasomal protein catabolic process;GO:1901292//nucleoside phosphate catabolic process	--
ENSG00000136160	0.837	0.706	1.555	0.441	0.212	1.057	67	54	85	29	16	55	EDNRB	endothelin receptor type B [Source:HGNC Symbol;Acc:HGNC:3180]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Signal transduction;Endocrine system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04926//Relaxin signaling pathway;ko04916//Melanogenesis	K04198;K04198;K04198;K04198;K04198;K04198	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0045121//membrane raft	GO:0004930//G protein-coupled receptor activity;GO:0004962//endothelin receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0031702//type 1 angiotensin receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0002001//renin secretion into blood stream;GO:0002027//regulation of heart rate;GO:0006885//regulation of pH;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0007497//posterior midgut development;GO:0007568//aging;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0010033//response to organic substance;GO:0010467//gene expression;GO:0014043//negative regulation of neuron maturation;GO:0014070//response to organic cyclic compound;GO:0014826//vein smooth muscle contraction;GO:0019233//sensory perception of pain;GO:0019722//calcium-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0030202//heparin metabolic process;GO:0030318//melanocyte differentiation;GO:0031620//regulation of fever generation;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032341//aldosterone metabolic process;GO:0032496//response to lipopolysaccharide;GO:0035645//enteric smooth muscle cell differentiation;GO:0035810//positive regulation of urine volume;GO:0035812//renal sodium excretion;GO:0035815//positive regulation of renal sodium excretion;GO:0042045//epithelial fluid transport;GO:0042310//vasoconstriction;GO:0042311//vasodilation;GO:0043066//negative regulation of apoptotic process;GO:0043473//pigmentation;GO:0048066//developmental pigmentation;GO:0048246//macrophage chemotaxis;GO:0048265//response to pain;GO:0048484//enteric nervous system development;GO:0050678//regulation of epithelial cell proliferation;GO:0051930//regulation of sensory perception of pain;GO:0055078//sodium ion homeostasis;GO:0060070//canonical Wnt signaling pathway;GO:0060406//positive regulation of penile erection;GO:0060465//pharynx development;GO:0061028//establishment of endothelial barrier;GO:0070294//renal sodium ion absorption;GO:0070588//calcium ion transmembrane transport;GO:0071222//cellular response to lipopolysaccharide;GO:0071806//protein transmembrane transport;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0086100//endothelin receptor signaling pathway;GO:0097018//renal albumin absorption;GO:1904383//response to sodium phosphate;GO:1990839//response to endothelin	--
ENSG00000136161	7.621	7.706	7.22	8.04	8.022	7.916	482	491	338	375	430	364	RCBTB2	RCC1 and BTB domain containing protein 2 [Source:HGNC Symbol;Acc:HGNC:1914]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000136167	1.587	1.814	0.555	0.376	0.413	0.32	101	97	31	7	19	9	LCP1	lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528]	-	-	-	-	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0001891//phagocytic cup;GO:0002102//podosome;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0032432//actin filament bundle;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0051020//GTPase binding	GO:0002286//T cell activation involved in immune response;GO:0010737//protein kinase A signaling;GO:0016477//cell migration;GO:0022617//extracellular matrix disassembly;GO:0030866//cortical actin cytoskeleton organization;GO:0031100//animal organ regeneration;GO:0033157//regulation of intracellular protein transport;GO:0051017//actin filament bundle assembly;GO:0051639//actin filament network formation;GO:0051764//actin crosslink formation;GO:0071803//positive regulation of podosome assembly	--
ENSG00000136169	4.574	3.719	4.409	3.905	4.171	4.606	588	481	419	372	453	418	SETDB2	SET domain bifurcated histone lysine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:20263]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K18494;K18494	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific)	"GO:0000278//mitotic cell cycle;GO:0001947//heart looping;GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0010629//negative regulation of gene expression;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0051567//histone H3-K9 methylation;GO:0070828//heterochromatin organization;GO:0070986//left/right axis specification;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly"	MBD
ENSG00000136193	46.479	46.193	46.49	39.493	41.466	45.091	5050	5060	3742	3188	3789	3535	SCRN1	secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016805//dipeptidase activity;GO:0070004//cysteine-type exopeptidase activity	GO:0006508//proteolysis;GO:0006887//exocytosis	--
ENSG00000136197	4.703	4.05	4.331	3.69	6.107	3.947	170.65	150.77	119.31	101.96	191.67	98.45	C7orf25	chromosome 7 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:21703]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000136205	96.869	104.252	98.586	75.43	81.36	64.282	15127	16329	11363	8774	10761	7313	TNS3	tensin 3 [Source:HGNC Symbol;Acc:HGNC:21616]	-	-	-	-	GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0005515//protein binding;GO:0016791//phosphatase activity	GO:0016311//dephosphorylation	--
ENSG00000136206	0	0.049	0.175	0.118	0.113	0.015	0	3	8	5	5.71	0.69	SPDYE1	speedy/RINGO cell cycle regulator family member E1 [Source:HGNC Symbol;Acc:HGNC:16408]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000136213	5.702	7.013	6.898	8.289	6.577	6.982	281.38	331.17	239.04	249.12	258.35	214.38	CHST12	carbohydrate sulfotransferase 12 [Source:HGNC Symbol;Acc:HGNC:17423]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K04742	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0098791//Golgi apparatus subcompartment	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047756//chondroitin 4-sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding	GO:0005975//carbohydrate metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030208//dermatan sulfate biosynthetic process	--
ENSG00000136231	8.773	7.281	9.566	9.396	8.534	8.813	777.77	638.24	600.34	611.79	631.63	563.19	IGF2BP3	insulin like growth factor 2 mRNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:28868]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0045182//translation regulator activity;GO:0048027//mRNA 5'-UTR binding;GO:1990247//N6-methyladenosine-containing RNA binding	GO:0001817//regulation of cytokine production;GO:0006412//translation;GO:0006417//regulation of translation;GO:0007399//nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0017148//negative regulation of translation;GO:0051028//mRNA transport;GO:0051252//regulation of RNA metabolic process;GO:0070934//CRD-mediated mRNA stabilization	--
ENSG00000136235	1102.381	1149.565	1138.356	1038.899	1033.843	1176.566	60139	63052	45916	42062	47701	46789	GPNMB	glycoprotein nmb [Source:HGNC Symbol;Acc:HGNC:4462]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0033162//melanosome membrane	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0045545//syndecan binding;GO:0048018//receptor ligand activity	GO:0001818//negative regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008285//negative regulation of cell population proliferation;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034103//regulation of tissue remodeling;GO:0042130//negative regulation of T cell proliferation;GO:0045765//regulation of angiogenesis;GO:0050868//negative regulation of T cell activation;GO:0050918//positive chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1901215//negative regulation of neuron death;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000136237	0.587	0.509	0.553	0.489	0.636	0.469	75	67	53	33	57	44	RAPGEF5	Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway	K08019;K08019	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016604//nuclear body	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0030742//GTP-dependent protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000136238	96.138	85.168	90.06	95.791	95.313	90.424	4478	4043	3144	3341	3746	3056	RAC1	Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Cellular community - eukaryotes;Immune system;Signal transduction;Endocrine and metabolic disease;Immune system;Cardiovascular disease;Immune system;Cardiovascular disease;Development and regeneration;Nervous system;Signal transduction;Immune system;Immune system;Cancer: overview;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Infectious disease: bacterial;Signal transduction	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko04310//Wnt signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04662//B cell receptor signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05210//Colorectal cancer;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05211//Renal cell carcinoma;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway	K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392;K04392	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030667//secretory granule membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043020//NADPH oxidase complex;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0101003//ficolin-1-rich granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031996//thioesterase binding;GO:0044877//protein-containing complex binding;GO:0051022//Rho GDP-dissociation inhibitor binding	"GO:0001764//neuron migration;GO:0001934//positive regulation of protein phosphorylation;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006954//inflammatory response;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008045//motor neuron axon guidance;GO:0008360//regulation of cell shape;GO:0008361//regulation of cell size;GO:0009611//response to wounding;GO:0009653//anatomical structure morphogenesis;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0010591//regulation of lamellipodium assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0010595//positive regulation of endothelial cell migration;GO:0010764//negative regulation of fibroblast migration;GO:0010811//positive regulation of cell-substrate adhesion;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030334//regulation of cell migration;GO:0030865//cortical cytoskeleton organization;GO:0031116//positive regulation of microtubule polymerization;GO:0031529//ruffle organization;GO:0032707//negative regulation of interleukin-23 production;GO:0032956//regulation of actin cytoskeleton organization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0043652//engulfment of apoptotic cell;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0045730//respiratory burst;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0048870//cell motility;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051668//localization within membrane;GO:0051894//positive regulation of focal adhesion assembly;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060263//regulation of respiratory burst;GO:0071526//semaphorin-plexin signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0097178//ruffle assembly;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902622//regulation of neutrophil migration"	--
ENSG00000136240	70.394	74.177	68.483	64.31	63.705	65.118	4022	4262.92	2864.99	2714	3072.98	2722	KDELR2	KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305]	Human Diseases	Infectious disease: bacterial	ko05110//Vibrio cholerae infection	K10949	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005046//KDEL sequence binding;GO:0046923//ER retention sequence binding	"GO:0006621//protein retention in ER lumen;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0035437//maintenance of protein localization in endoplasmic reticulum"	--
ENSG00000136243	6.453	5.168	6.041	7.408	4.812	5.199	209	165	146	164	133	118	NUP42	nucleoporin 42 [Source:HGNC Symbol;Acc:HGNC:17010]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14321	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0003723//RNA binding;GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006611//protein export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000136244	0.977	0.57	0.805	1.309	0.57	1.074	17	9	11	19	10	15	IL6	interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signaling molecules and interaction;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Immune system;Signal transduction;Endocrine and metabolic disease;Infectious disease: viral;Immune disease;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Immune system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Signaling molecules and interaction;Immune system;Cardiovascular disease;Drug resistance: antineoplastic;Infectious disease: bacterial;Immune disease;Immune system;Infectious disease: bacterial;Infectious disease: parasitic;Immune disease;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko05162//Measles;ko04936//Alcoholic liver disease;ko04068//FoxO signaling pathway;ko04672//Intestinal immune network for IgA production;ko04066//HIF-1 signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis;ko05144//Malaria;ko05332//Graft-versus-host disease;ko01523//Antifolate resistance	K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405;K05405	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005896//interleukin-6 receptor complex	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0001781//neutrophil apoptotic process;GO:0002314//germinal center B cell differentiation;GO:0002384//hepatic immune response;GO:0002446//neutrophil mediated immunity;GO:0002548//monocyte chemotaxis;GO:0002639//positive regulation of immunoglobulin production;GO:0002675//positive regulation of acute inflammatory response;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010573//vascular endothelial growth factor production;GO:0010574//regulation of vascular endothelial growth factor production;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010888//negative regulation of lipid storage;GO:0014823//response to activity;GO:0019221//cytokine-mediated signaling pathway;GO:0030168//platelet activation;GO:0031018//endocrine pancreas development;GO:0031175//neuron projection development;GO:0032494//response to peptidoglycan;GO:0032682//negative regulation of chemokine production;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032745//positive regulation of interleukin-21 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032966//negative regulation of collagen biosynthetic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035633//maintenance of blood-brain barrier;GO:0042102//positive regulation of T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045727//positive regulation of translation;GO:0045765//regulation of angiogenesis;GO:0045779//negative regulation of bone resorption;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050768//negative regulation of neurogenesis;GO:0050796//regulation of insulin secretion;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050871//positive regulation of B cell activation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051384//response to glucocorticoid;GO:0051607//defense response to virus;GO:0060252//positive regulation of glial cell proliferation;GO:0061470//T follicular helper cell differentiation;GO:0061888//regulation of astrocyte activation;GO:0070050//neuron cellular homeostasis;GO:0070091//glucagon secretion;GO:0070092//regulation of glucagon secretion;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0071222//cellular response to lipopolysaccharide;GO:0072540//T-helper 17 cell lineage commitment;GO:0072574//hepatocyte proliferation;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0097421//liver regeneration;GO:0098586//cellular response to virus;GO:0150077//regulation of neuroinflammatory response;GO:0150078//positive regulation of neuroinflammatory response;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1901731//positive regulation of platelet aggregation;GO:1902512//positive regulation of apoptotic DNA fragmentation;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:1903978//regulation of microglial cell activation;GO:1904894//positive regulation of receptor signaling pathway via STAT;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2000635//negative regulation of primary miRNA processing;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:2000676//positive regulation of type B pancreatic cell apoptotic process"	--
ENSG00000136247	35.645	34.942	43.504	43.319	36.845	34.478	1056	1082	912	945	946	787	ZDHHC4	zinc finger DHHC-type palmitoyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:18471]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation	--
ENSG00000136250	0	0	0	0	0	0	0	0	0	0	0	0	AOAH	acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548]	-	-	-	-	GO:0005576//extracellular region;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	"GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding;GO:0050528//acyloxyacyl hydrolase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008653//lipopolysaccharide metabolic process;GO:0009104//lipopolysaccharide catabolic process;GO:0050728//negative regulation of inflammatory response	--
ENSG00000136261	42.406	41.121	39.502	35.48	36.536	29.313	1438	1467	970	897	1052	800	BZW2	basic leucine zipper and W2 domains 2 [Source:HGNC Symbol;Acc:HGNC:18808]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0006446//regulation of translational initiation;GO:0007399//nervous system development;GO:0030154//cell differentiation	--
ENSG00000136267	0.205	0.187	0.057	0.235	0.114	0.151	26	17	6	17	11	12	DGKB	diacylglycerol kinase beta [Source:HGNC Symbol;Acc:HGNC:2850]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005509//calcium ion binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0009617//response to bacterium;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0044255//cellular lipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0050804//modulation of chemical synaptic transmission;GO:0099175//regulation of postsynapse organization	--
ENSG00000136270	16.519	15.381	18.124	20.733	20.455	19.139	731	699	603	666	766	601	TBRG4	transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000963//mitochondrial RNA processing;GO:0008284//positive regulation of cell population proliferation;GO:0016071//mRNA metabolic process;GO:0044528//regulation of mitochondrial mRNA stability;GO:0051726//regulation of cell cycle;GO:0090615//mitochondrial mRNA processing	--
ENSG00000136271	18.91	19.503	19.595	21.442	20.535	22.847	757	778	574	642	693	653	DDX56	DEAD-box helicase 56 [Source:HGNC Symbol;Acc:HGNC:18193]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006364//rRNA processing;GO:0010976//positive regulation of neuron projection development;GO:0042254//ribosome biogenesis	--
ENSG00000136273	7.719	6.121	8.85	6.32	5.66	7.02	292	240	248	186	206	183	HUS1	HUS1 checkpoint clamp component [Source:HGNC Symbol;Acc:HGNC:5309]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K10903	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030896//checkpoint clamp complex;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0001932//regulation of protein phosphorylation;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0009792//embryo development ending in birth or egg hatching;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0044778//meiotic DNA integrity checkpoint signaling;GO:0071479//cellular response to ionizing radiation	--
ENSG00000136274	1.615	2.023	2.551	1.709	2.065	1.891	162	204	189	127	175	138	NACAD	NAC alpha domain containing [Source:HGNC Symbol;Acc:HGNC:22196]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005854//nascent polypeptide-associated complex	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006612//protein targeting to membrane;GO:0015031//protein transport	--
ENSG00000136279	41.147	45.543	47.006	47.316	46.112	38.835	1750.46	1915.72	1398.61	1410.34	1533.04	1201.9	DBNL	drebrin like [Source:HGNC Symbol;Acc:HGNC:2696]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0002102//podosome;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030427//site of polarized growth;GO:0030665//clathrin-coated vesicle membrane;GO:0030864//cortical actin cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0043226//organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007416//synapse assembly;GO:0016601//Rac protein signal transduction;GO:0030833//regulation of actin filament polymerization;GO:0045773//positive regulation of axon extension;GO:0048812//neuron projection morphogenesis;GO:0050790//regulation of catalytic activity;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071800//podosome assembly;GO:0097178//ruffle assembly;GO:0098974//postsynaptic actin cytoskeleton organization	--
ENSG00000136280	10.977	10.73	11.396	12.723	12.696	11.411	424	416	308	356	388	316	CCM2	CCM2 scaffold protein [Source:HGNC Symbol;Acc:HGNC:21708]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001885//endothelial cell development;GO:0001944//vasculature development;GO:0003158//endothelium development;GO:0007229//integrin-mediated signaling pathway;GO:0007507//heart development;GO:0035264//multicellular organism growth;GO:0045216//cell-cell junction organization;GO:0045765//regulation of angiogenesis;GO:0048839//inner ear development;GO:0048845//venous blood vessel morphogenesis;GO:0051403//stress-activated MAPK cascade;GO:0060039//pericardium development;GO:0060837//blood vessel endothelial cell differentiation;GO:0061154//endothelial tube morphogenesis	--
ENSG00000136286	0	0	0	0	0.022	0	0	0	0	0	1	0	MYO1G	myosin IG [Source:HGNC Symbol;Acc:HGNC:13880]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0001891//phagocytic cup;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031256//leading edge membrane;GO:0031982//vesicle;GO:0042995//cell projection;GO:0070062//extracellular exosome	"GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0051015//actin filament binding"	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0006887//exocytosis;GO:0006909//phagocytosis;GO:0007015//actin filament organization;GO:0030050//vesicle transport along actin filament;GO:0031589//cell-substrate adhesion;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0071976//cell gliding;GO:0072678//T cell migration;GO:0120117//T cell meandering migration	--
ENSG00000136295	58.14	59.145	58.795	77.524	70.003	72.186	5608	5729	4268	5563	5721	5137	TTYH3	tweety family member 3 [Source:HGNC Symbol;Acc:HGNC:22222]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0070062//extracellular exosome	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0072320//volume-sensitive chloride channel activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport	--
ENSG00000136297	0.146	0	0.028	0	0	0	7	0	1	0	0	0	MMD2	monocyte to macrophage differentiation associated 2 [Source:HGNC Symbol;Acc:HGNC:30133]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004672//protein kinase activity;GO:0005515//protein binding	GO:0006468//protein phosphorylation;GO:0019835//cytolysis;GO:0032880//regulation of protein localization;GO:0045666//positive regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046579//positive regulation of Ras protein signal transduction	--
ENSG00000136305	0.37	0.333	0.161	0.132	0.199	0.181	11.2	9.51	5.67	2.48	8.26	6.28	CIDEB	cell death inducing DFFA like effector b [Source:HGNC Symbol;Acc:HGNC:1977]	-	-	-	-	GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010942//positive regulation of cell death;GO:0031667//response to nutrient levels;GO:0038183//bile acid signaling pathway;GO:0042981//regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097194//execution phase of apoptosis;GO:0097202//activation of cysteine-type endopeptidase activity	--
ENSG00000136319	6.986	7.644	6.826	6.917	6.991	5.877	542	598	393	381	399	307	TTC5	tetratricopeptide repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:19274]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009267//cellular response to starvation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061014//positive regulation of mRNA catabolic process	--
ENSG00000136327	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-8	NK2 homeobox 8 [Source:HGNC Symbol;Acc:HGNC:16364]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001889//liver development;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0030154//cell differentiation;GO:0030323//respiratory tube development;GO:0030324//lung development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050680//negative regulation of epithelial cell proliferation"	Homeobox
ENSG00000136352	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-1	NK2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11825]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001161//intronic transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0009725//response to hormone;GO:0010628//positive regulation of gene expression;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0021759//globus pallidus development;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030878//thyroid gland development;GO:0030900//forebrain development;GO:0042753//positive regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0060441//epithelial tube branching involved in lung morphogenesis"	Homeobox
ENSG00000136367	1.925	1.589	2.021	1.169	2.235	1.786	287	308	228	167	268	199	ZFHX2	zinc finger homeobox 2 [Source:HGNC Symbol;Acc:HGNC:20152]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0030534//adult behavior;GO:0045664//regulation of neuron differentiation;GO:0051930//regulation of sensory perception of pain"	Homeobox
ENSG00000136371	8.74	6.605	6.477	9.492	8.073	6.788	129.5	109	77.46	105.74	105.13	72.25	MTHFS	methenyltetrahydrofolate synthetase [Source:HGNC Symbol;Acc:HGNC:7437]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K01934;K01934	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0005542//folic acid binding;GO:0016874//ligase activity;GO:0030272//5-formyltetrahydrofolate cyclo-ligase activity;GO:0046872//metal ion binding	GO:0006536//glutamate metabolic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0015942//formate metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0046653//tetrahydrofolate metabolic process;GO:0046655//folic acid metabolic process;GO:0046657//folic acid catabolic process	--
ENSG00000136378	11.695	13.19	11.672	12.168	12.312	10.491	1339	1518	987	1032	1191	874	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001503//ossification;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0032331//negative regulation of chondrocyte differentiation;GO:0043931//ossification involved in bone maturation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071773//cellular response to BMP stimulus	--
ENSG00000136379	3.392	3.21	2.461	3.418	4.373	3.255	166	158	89	124	150	116	ABHD17C	"abhydrolase domain containing 17C, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:26925]"	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055038//recycling endosome membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity	GO:0002084//protein depalmitoylation;GO:0099175//regulation of postsynapse organization;GO:1902817//negative regulation of protein localization to microtubule;GO:1905668//positive regulation of protein localization to endosome	--
ENSG00000136381	19.55	20.638	16.832	12.966	16.134	17.88	2255	1809	1383	1044	1457	1373	IREB2	iron responsive element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6115]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0003723//RNA binding;GO:0003994//aconitate hydratase activity;GO:0005515//protein binding;GO:0030350//iron-responsive element binding;GO:0030371//translation repressor activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006099//tricarboxylic acid cycle;GO:0006101//citrate metabolic process;GO:0006417//regulation of translation;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0017148//negative regulation of translation;GO:0030316//osteoclast differentiation;GO:0034101//erythrocyte homeostasis;GO:0050892//intestinal absorption;GO:0055072//iron ion homeostasis	--
ENSG00000136383	1.352	1.181	1.116	0.725	0.764	1.12	287	252	175	114	137	173	ALPK3	alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574]	-	-	-	-	GO:0005634//nucleus	GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007507//heart development;GO:0016310//phosphorylation;GO:0055013//cardiac muscle cell development	--
ENSG00000136404	0	0	0	0	0	0.084	0	0	0	0	0	1.87	TM6SF1	transmembrane 6 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11860]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000136425	7.115	6.988	8.798	9.344	9.507	6.743	200	195	167	163	192	121	CIB2	calcium and integrin binding family member 2 [Source:HGNC Symbol;Acc:HGNC:24579]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005927//muscle tendon junction;GO:0005929//cilium;GO:0016020//membrane;GO:0031594//neuromuscular junction;GO:0032420//stereocilium;GO:0032437//cuticular plate;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0072562//blood microparticle	GO:0000287//magnesium ion binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045494//photoreceptor cell maintenance;GO:0055074//calcium ion homeostasis;GO:0071318//cellular response to ATP	--
ENSG00000136436	61.158	64.838	67.483	56.356	65.344	71.186	2257	2237	1901	1525	1987	1833	CALCOCO2	calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism	ko05131//Shigellosis;ko05164//Influenza A;ko04137//Mitophagy - animal	K21348;K21348;K21348	GO:0000421//autophagosome membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016605//PML body;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006914//autophagy;GO:0016032//viral process;GO:0034341//response to interferon-gamma;GO:0098792//xenophagy;GO:1901098//positive regulation of autophagosome maturation	--
ENSG00000136444	9.771	11	12.26	11.742	12.311	12.704	500	562	459	441	503	473	RSAD1	radical S-adenosyl methionine domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25634]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005739//mitochondrion	"GO:0003824//catalytic activity;GO:0004109//coproporphyrinogen oxidase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0008150//biological_process	--
ENSG00000136448	36.731	37.594	38.866	37.013	36.55	36.65	2702	2820	2100	2065	2348	1940	NMT1	N-myristoyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:7857]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane	GO:0004379//glycylpeptide N-tetradecanoyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019107//myristoyltransferase activity	GO:0001701//in utero embryonic development;GO:0006499//N-terminal protein myristoylation;GO:0018008//N-terminal peptidyl-glycine N-myristoylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042180//cellular ketone metabolic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	--
ENSG00000136449	0.249	0.248	0.329	0.195	0.206	0.085	16	13	13	5	8	4	MYCBPAP	MYCBP associated protein [Source:HGNC Symbol;Acc:HGNC:19677]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0045202//synapse	GO:0005515//protein binding	GO:0007268//chemical synaptic transmission;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000136450	66.011	66.235	69.394	68.606	65.132	70.731	3612.51	3556.34	2676.86	2700.42	2860.17	2651.92	SRSF1	serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780]	Human Diseases;Genetic Information Processing;Organismal Systems	Infectious disease: viral;Transcription;Immune system	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome;ko04657//IL-17 signaling pathway	K12890;K12890;K12890	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044547//DNA topoisomerase binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0051028//mRNA transport"	--
ENSG00000136451	22.677	18.689	18.319	14.769	16.013	17.56	1656	1383	1072	844	992	993	VEZF1	vascular endothelial zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:12949]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0001525//angiogenesis;GO:0001885//endothelial cell development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006968//cellular defense response;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000136457	0.162	0	0.268	0.038	0.1	0.039	2	0	7	1	3	1	CHAD	chondroadherin [Source:HGNC Symbol;Acc:HGNC:1909]	Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04512//ECM-receptor interaction	K06248;K06248;K06248;K06248	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0060348//bone development;GO:1900155//negative regulation of bone trabecula formation	--
ENSG00000136463	10.302	10.216	12.042	12.545	9.707	13.069	309	304.35	263	277	244.19	283	TACO1	translational activator of cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:24316]	-	-	-	-	GO:0005739//mitochondrion	GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0097177//mitochondrial ribosome binding	GO:0006417//regulation of translation;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0061743//motor learning;GO:0070129//regulation of mitochondrial translation;GO:1904959//regulation of cytochrome-c oxidase activity	--
ENSG00000136478	90.052	88.473	77.602	70.177	73.572	78.988	9141	9038	5799	5229	6191	5633	TEX2	testis expressed 2 [Source:HGNC Symbol;Acc:HGNC:30884]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003674//molecular_function;GO:0008289//lipid binding	GO:0006665//sphingolipid metabolic process;GO:0006869//lipid transport;GO:0007165//signal transduction	--
ENSG00000136485	50.799	48.929	53.293	54.152	55.445	52.811	5165	5265.28	4055	4241	4780.14	4089	DCAF7	DDB1 and CUL4 associated factor 7 [Source:HGNC Symbol;Acc:HGNC:30915]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0016567//protein ubiquitination	--
ENSG00000136487	0	0	0	0	0	0	0	0	0	0	0	0	GH2	growth hormone 2 [Source:HGNC Symbol;Acc:HGNC:4262]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031904//endosome lumen;GO:0031982//vesicle	GO:0005131//growth hormone receptor binding;GO:0005179//hormone activity;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0031667//response to nutrient levels;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0060396//growth hormone receptor signaling pathway	--
ENSG00000136488	0	0	0	0	0	0	0	0	0	0	0	0	CSH1	chorionic somatomammotropin hormone 1 [Source:HGNC Symbol;Acc:HGNC:2440]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031904//endosome lumen;GO:0031982//vesicle	GO:0005131//growth hormone receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0031667//response to nutrient levels;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0060396//growth hormone receptor signaling pathway	--
ENSG00000136490	3.747	4.782	4.811	4.441	5.247	3.745	118.49	135.2	122.91	112.93	108.32	77	LIMD2	LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000136492	0.214	0.153	0.453	0.203	0.316	0.183	22	17	14	13	21	13	BRIP1	BRCA1 interacting helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K15362;K15362	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0070532//BRCA1-B complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0043139//5'-3' DNA helicase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0000077//DNA damage checkpoint signaling;GO:0006139//nucleobase-containing compound metabolic process;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006302//double-strand break repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0007284//spermatogonial cell division;GO:0007286//spermatid development;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009636//response to toxic substance;GO:0010629//negative regulation of gene expression;GO:0010705//meiotic DNA double-strand break processing involved in reciprocal meiotic recombination;GO:0032508//DNA duplex unwinding;GO:0035825//homologous recombination;GO:0051026//chiasma assembly;GO:0071295//cellular response to vitamin;GO:0071456//cellular response to hypoxia;GO:0072520//seminiferous tubule development;GO:1904385//cellular response to angiotensin;GO:1990918//double-strand break repair involved in meiotic recombination	--
ENSG00000136504	16.74	18.868	17.973	16.98	18.688	16.859	1170	1303	925	908	1081	870	KAT7	lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016]	-	-	-	-	"GO:0000123//histone acetyltransferase complex;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0036409//histone H3-K14 acetyltransferase complex;GO:0090734//site of DNA damage"	GO:0003688//DNA replication origin binding;GO:0003712//transcription coregulator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0001779//natural killer cell differentiation;GO:0006260//DNA replication;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0016570//histone modification;GO:0016573//histone acetylation;GO:0018393//internal peptidyl-lysine acetylation;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0031098//stress-activated protein kinase signaling cascade;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045740//positive regulation of DNA replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0072708//response to sorbitol;GO:0072710//response to hydroxyurea;GO:0072716//response to actinomycin D;GO:0072720//response to dithiothreitol;GO:0072739//response to anisomycin;GO:0090240//positive regulation of histone H4 acetylation;GO:1900182//positive regulation of protein localization to nucleus;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:2000278//regulation of DNA biosynthetic process;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000136514	0.739	0.799	1.261	0.954	0.988	0.618	23	25	29	22	26	14	RTP4	receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031849//olfactory receptor binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006612//protein targeting to membrane;GO:0051205//protein insertion into membrane;GO:0051607//defense response to virus	--
ENSG00000136518	25.834	24.802	29.289	27.242	24.444	26.96	985	950	825	772	788	752	ACTL6A	actin like 6A [Source:HGNC Symbol;Acc:HGNC:24124]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11340;K11340	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0031011//Ino80 complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0071564//npBAF complex;GO:0140288//GBAF complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding	"GO:0000723//telomere maintenance;GO:0001825//blastocyst formation;GO:0003407//neural retina development;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0016573//histone acetylation;GO:0021510//spinal cord development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0033044//regulation of chromosome organization;GO:0040008//regulation of growth;GO:0042766//nucleosome mobilization;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:1904507//positive regulation of telomere maintenance in response to DNA damage;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000779//regulation of double-strand break repair;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000136521	73.017	74.64	80.346	86.951	77.687	73.645	1686	1751.34	1373.77	1523.27	1505	1281	NDUFB5	NADH:ubiquinone oxidoreductase subunit B5 [Source:HGNC Symbol;Acc:HGNC:7700]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000136522	14.629	16.284	15.641	14.062	13.163	12.834	349	399	290	255	258	243	MRPL47	mitochondrial ribosomal protein L47 [Source:HGNC Symbol;Acc:HGNC:16652]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003674//molecular_function;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0008150//biological_process;GO:0032543//mitochondrial translation	--
ENSG00000136527	41.347	39.577	41.624	38.3	40.914	32.975	1565	1503	1119	1053	1229	935	TRA2B	transformer 2 beta homolog [Source:HGNC Symbol;Acc:HGNC:10781]	Human Diseases;Genetic Information Processing	Endocrine and metabolic disease;Transcription	ko04936//Alcoholic liver disease;ko03040//Spliceosome	K12897;K12897	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0036002//pre-mRNA binding;GO:0042802//identical protein binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0021796//cerebral cortex regionalization;GO:0043484//regulation of RNA splicing;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0071333//cellular response to glucose stimulus;GO:1990403//embryonic brain development"	--
ENSG00000136531	0.575	0.305	0.394	0.243	0.287	0.463	87	55	39	32	40	61	SCN2A	sodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588]	Organismal Systems	Sensory system	ko04742//Taste transduction	K04834	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0033268//node of Ranvier;GO:0033270//paranode region of axon;GO:0034706//sodium channel complex;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007399//nervous system development;GO:0007613//memory;GO:0008627//intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042552//myelination;GO:0051402//neuron apoptotic process;GO:0055085//transmembrane transport;GO:0071456//cellular response to hypoxia;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000136535	0	0	0	0	0	0	0	0	0	0	0	0	TBR1	T-box brain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11590]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding"	"GO:0001661//conditioned taste aversion;GO:0001708//cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0010092//specification of animal organ identity;GO:0010468//regulation of gene expression;GO:0010975//regulation of neuron projection development;GO:0021764//amygdala development;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0021987//cerebral cortex development;GO:0030182//neuron differentiation;GO:0030902//hindbrain development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902667//regulation of axon guidance"	T-box
ENSG00000136536	32.969	27.134	26.331	19.043	23.806	26.801	2196.27	1729.11	1223.28	1057.07	1223.9	1316.46	MARCHF7	membrane associated ring-CH-type finger 7 [Source:HGNC Symbol;Acc:HGNC:17393]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0097371//MDM2/MDM4 family protein binding	"GO:0002643//regulation of tolerance induction;GO:0006513//protein monoubiquitination;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0042130//negative regulation of T cell proliferation;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0050821//protein stabilization;GO:0051865//protein autoubiquitination;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1902916//positive regulation of protein polyubiquitination;GO:1905524//negative regulation of protein autoubiquitination"	--
ENSG00000136541	46.479	43.798	37.005	25.897	29.617	22.546	2470	2429	1381	1131	1384	864	ERMN	ermin [Source:HGNC Symbol;Acc:HGNC:29208]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0030175//filopodium;GO:0033269//internode region of axon;GO:0033270//paranode region of axon;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0001763//morphogenesis of a branching structure;GO:0007015//actin filament organization;GO:0008360//regulation of cell shape;GO:0031344//regulation of cell projection organization	--
ENSG00000136542	0.55	0.492	0.271	0.195	0.254	0.109	118	106	43	31	46	17	GALNT5	polypeptide N-acetylgalactosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:4127]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0016266//O-glycan processing	--
ENSG00000136546	0.009	0	0	0	0	0.025	1	0	0	0	0	2	SCN7A	sodium voltage-gated channel alpha subunit 7 [Source:HGNC Symbol;Acc:HGNC:10594]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04839	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0097386//glial cell projection	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006936//muscle contraction;GO:0009617//response to bacterium;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055078//sodium ion homeostasis;GO:0055085//transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000136560	14.859	11.249	13.031	10.297	10.53	13.895	549	432	357	264	321	382	TANK	TRAF family member associated NFKB activator [Source:HGNC Symbol;Acc:HGNC:11562]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Immune system;Transport and catabolism;Immune system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05417//Lipid and atherosclerosis;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04622//RIG-I-like receptor signaling pathway	K12650;K12650;K12650;K12650;K12650;K12650	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:1902554//serine/threonine protein kinase complex	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035800//deubiquitinase activator activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071479//cellular response to ionizing radiation;GO:1903003//positive regulation of protein deubiquitination;GO:2000158//positive regulation of ubiquitin-specific protease activity	--
ENSG00000136573	0	0	0	0	0.026	0	0	0	0	0	1	0	BLK	"BLK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1057]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0002513//tolerance induction to self antigen;GO:0002576//platelet degranulation;GO:0002902//regulation of B cell apoptotic process;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030889//negative regulation of B cell proliferation;GO:0031175//neuron projection development;GO:0032024//positive regulation of insulin secretion;GO:0032092//positive regulation of protein binding;GO:0035556//intracellular signal transduction;GO:0043304//regulation of mast cell degranulation;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050855//regulation of B cell receptor signaling pathway;GO:0070667//negative regulation of mast cell proliferation;GO:0090330//regulation of platelet aggregation;GO:0097028//dendritic cell differentiation;GO:2000670//positive regulation of dendritic cell apoptotic process	--
ENSG00000136574	0.129	0.073	0	0.05	0	0.025	7	4	0	2	0	1	GATA4	GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173]	Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems	Cellular community - eukaryotes;Signal transduction;Cell growth and death;Endocrine system	ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04919//Thyroid hormone signaling pathway	K09183;K09183;K09183;K09183	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051525//NFAT protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070410//co-SMAD binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001947//heart looping;GO:0003162//atrioventricular node development;GO:0003180//aortic valve morphogenesis;GO:0003190//atrioventricular valve formation;GO:0003197//endocardial cushion development;GO:0003208//cardiac ventricle morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003281//ventricular septum development;GO:0003289//atrial septum primum morphogenesis;GO:0003290//atrial septum secundum morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0007492//endoderm development;GO:0007507//heart development;GO:0007596//blood coagulation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009653//anatomical structure morphogenesis;GO:0010507//negative regulation of autophagy;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0030154//cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0033189//response to vitamin A;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0036302//atrioventricular canal development;GO:0042060//wound healing;GO:0045165//cell fate commitment;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development;GO:0048617//embryonic foregut morphogenesis;GO:0051891//positive regulation of cardioblast differentiation;GO:0051896//regulation of protein kinase B signaling;GO:0055007//cardiac muscle cell differentiation;GO:0060290//transdifferentiation;GO:0060413//atrial septum morphogenesis;GO:0060575//intestinal epithelial cell differentiation;GO:0061026//cardiac muscle tissue regeneration;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0086004//regulation of cardiac muscle cell contraction;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:2001234//negative regulation of apoptotic signaling pathway"	zf-GATA
ENSG00000136603	6.064	4.275	3.153	2.218	3.53	3.333	674	465	290	205	290	268	SKIL	SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18499	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0032991//protein-containing complex;GO:0110165//cellular anatomical entity	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0046332//SMAD binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001825//blastocyst formation;GO:0002260//lymphocyte homeostasis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007519//skeletal muscle tissue development;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0034097//response to cytokine;GO:0045596//negative regulation of cell differentiation;GO:0046677//response to antibiotic;GO:0050772//positive regulation of axonogenesis;GO:0051726//regulation of cell cycle;GO:0070306//lens fiber cell differentiation;GO:0070848//response to growth factor;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	--
ENSG00000136628	25.474	21.866	19.414	15.087	17.255	21.394	2569	2209	1446	1127	1447	1566	EPRS1	glutamyl-prolyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:3418]	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00860//Porphyrin metabolism	K14163;K14163;K14163	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0097452//GAIT complex;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004818//glutamate-tRNA ligase activity;GO:0004827//proline-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0035613//RNA stem-loop binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051020//GTPase binding	GO:0006412//translation;GO:0006417//regulation of translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006424//glutamyl-tRNA aminoacylation;GO:0006433//prolyl-tRNA aminoacylation;GO:0008152//metabolic process;GO:0017148//negative regulation of translation;GO:0032869//cellular response to insulin stimulus;GO:0043039//tRNA aminoacylation;GO:0065003//protein-containing complex assembly;GO:0071346//cellular response to interferon-gamma;GO:0140212//regulation of long-chain fatty acid import into cell	--
ENSG00000136630	0	0	0	0	0	0	0	0	0	0	0	0	HLX	H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001889//liver development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007519//skeletal muscle tissue development;GO:0008284//positive regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0046622//positive regulation of organ growth;GO:0048484//enteric nervous system development;GO:0048513//animal organ development;GO:0048557//embryonic digestive tract morphogenesis"	Homeobox
ENSG00000136631	14.922	13.509	13.053	10.157	11.765	12.005	721	652	467	364	475	422	VPS45	vacuolar protein sorting 45 homolog [Source:HGNC Symbol;Acc:HGNC:14579]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12479	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000136634	0	0	0	0	0	0	0	0	0	0	0	0	IL10	interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Signaling molecules and interaction;Infectious disease: bacterial;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic;Infectious disease: bacterial;Signal transduction;Infectious disease: parasitic;Signal transduction;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Immune disease;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune disease;Signaling molecules and interaction;Infectious disease: bacterial;Immune disease;Infectious disease: parasitic	ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko05146//Amoebiasis;ko05150//Staphylococcus aureus infection;ko04630//JAK-STAT signaling pathway;ko05140//Leishmaniasis;ko04068//FoxO signaling pathway;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko05143//African trypanosomiasis;ko05310//Asthma;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko05144//Malaria	K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443;K05443	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005141//interleukin-10 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0046983//protein dimerization activity	"GO:0001817//regulation of cytokine production;GO:0001818//negative regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002237//response to molecule of bacterial origin;GO:0002639//positive regulation of immunoglobulin production;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0002875//negative regulation of chronic inflammatory response to antigenic stimulus;GO:0002904//positive regulation of B cell apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0007568//aging;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010468//regulation of gene expression;GO:0010507//negative regulation of autophagy;GO:0014823//response to activity;GO:0014854//response to inactivity;GO:0030097//hemopoiesis;GO:0030183//B cell differentiation;GO:0030595//leukocyte chemotaxis;GO:0030886//negative regulation of myeloid dendritic cell activation;GO:0030889//negative regulation of B cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0032687//negative regulation of interferon-alpha production;GO:0032689//negative regulation of interferon-gamma production;GO:0032692//negative regulation of interleukin-1 production;GO:0032695//negative regulation of interleukin-12 production;GO:0032701//negative regulation of interleukin-18 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032717//negative regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032868//response to insulin;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034465//response to carbon monoxide;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0042092//type 2 immune response;GO:0042100//B cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0043032//positive regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045191//regulation of isotype switching;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045787//positive regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050728//negative regulation of inflammatory response;GO:0050807//regulation of synapse organization;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051384//response to glucocorticoid;GO:0051930//regulation of sensory perception of pain;GO:0060302//negative regulation of cytokine activity;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0071392//cellular response to estradiol stimulus;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0072577//endothelial cell apoptotic process;GO:0097421//liver regeneration;GO:1900100//positive regulation of plasma cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903034//regulation of response to wounding;GO:1903208//negative regulation of hydrogen peroxide-induced neuron death;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904057//negative regulation of sensory perception of pain;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000273//positive regulation of signaling receptor activity;GO:2000352//negative regulation of endothelial cell apoptotic process"	--
ENSG00000136636	17.346	16.78	14.618	12.35	12.935	12.695	1446	1406	900	738	911	770	KCTD3	potassium channel tetramerization domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21305]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0051260//protein homooligomerization	--
ENSG00000136643	5.339	5.188	4.955	3.689	4.332	3.936	473	483	330	256	333	276	RPS6KC1	ribosomal protein S6 kinase C1 [Source:HGNC Symbol;Acc:HGNC:10439]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035091//phosphatidylinositol binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation	--
ENSG00000136682	11.262	10.548	9.927	10.48	8.906	9.559	414	386.06	266.27	287.73	278.18	249.32	CBWD2	COBW domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17907]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000136688	0	0	0	0	0	0	0	0	0	0	0	0	IL36G	interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05487	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding	GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007267//cell-cell signaling;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000136689	0	0	0	0	0	0.06	0	0	0	0	0	1	IL1RN	interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05481	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	"GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005150//interleukin-1, type I receptor binding;GO:0005151//interleukin-1, type II receptor binding;GO:0005152//interleukin-1 receptor antagonist activity;GO:0005515//protein binding;GO:0045352//interleukin-1 type I receptor antagonist activity;GO:0045353//interleukin-1 type II receptor antagonist activity"	GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002437//inflammatory response to antigenic stimulus;GO:0006629//lipid metabolic process;GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0030073//insulin secretion;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0051384//response to glucocorticoid;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway	--
ENSG00000136694	0	0	0	0	0	0	0	0	0	0	0	0	IL36A	interleukin 36 alpha [Source:HGNC Symbol;Acc:HGNC:15562]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05484	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding	GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000136695	0	0	0	0	0	0	0	0	0	0	0	0	IL36RN	interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05483	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005152//interleukin-1 receptor antagonist activity;GO:0005515//protein binding	GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0019732//antifungal humoral response;GO:0032689//negative regulation of interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0032715//negative regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000136696	0	0	0	0	0	0	0	0	0	0	0	0	IL36B	interleukin 36 beta [Source:HGNC Symbol;Acc:HGNC:15564]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05486	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding	GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0045087//innate immune response;GO:0045582//positive regulation of T cell differentiation;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000136697	0	0	0	0	0	0	0	0	0	0	0	0	IL1F10	interleukin 1 family member 10 [Source:HGNC Symbol;Acc:HGNC:15552]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05488	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000136698	0	0	0	0	0	0	0	0	0	0	0	0	CFC1	"cripto, FRL-1, cryptic family 1 [Source:HGNC Symbol;Acc:HGNC:18292]"	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0038100//nodal binding;GO:0070697//activin receptor binding	GO:0001568//blood vessel development;GO:0007368//determination of left/right symmetry;GO:0007369//gastrulation;GO:0007507//heart development;GO:0009952//anterior/posterior pattern specification;GO:0038092//nodal signaling pathway;GO:0048856//anatomical structure development	--
ENSG00000136699	16.84	16.842	16.237	17.31	19.29	19.069	1173.13	1331.12	916	996.17	1138.08	1052.24	SMPD4	sphingomyelin phosphodiesterase 4 [Source:HGNC Symbol;Acc:HGNC:32949]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K12353;K12353	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0004767//sphingomyelin phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050290//sphingomyelin phosphodiesterase D activity	GO:0006629//lipid metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0007029//endoplasmic reticulum organization;GO:0046475//glycerophospholipid catabolic process;GO:0046513//ceramide biosynthetic process;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000136709	13.769	14.04	15.37	11.924	10.803	13.183	1578	1545	1174	1019	1264	1095.01	WDR33	WD repeat domain 33 [Source:HGNC Symbol;Acc:HGNC:25651]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15542	GO:0001650//fibrillar center;GO:0005581//collagen trimer;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006301//postreplication repair;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0031124//mRNA 3'-end processing	--
ENSG00000136710	12.514	11.538	13.525	13.724	14.826	13.878	411	391	360	346	424	337	CCDC115	coiled-coil domain containing 115 [Source:HGNC Symbol;Acc:HGNC:28178]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030137//COPI-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0042406//extrinsic component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006879//cellular iron ion homeostasis;GO:0007042//lysosomal lumen acidification;GO:0036295//cellular response to increased oxygen levels;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:1905146//lysosomal protein catabolic process	--
ENSG00000136715	11.005	10.13	10.169	9.544	9.894	8.78	885	863	583	558	686	543	SAP130	Sin3A associated protein 130 [Source:HGNC Symbol;Acc:HGNC:29813]	-	-	-	-	GO:0005634//nucleus;GO:0016580//Sin3 complex;GO:0016607//nuclear speck;GO:0070822//Sin3-type complex	-	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000136717	53.867	52.121	49.458	52.452	51.595	51.172	2442	2368	1659	1758	1980	1690	BIN1	bridging integrator 1 [Source:HGNC Symbol;Acc:HGNC:1052]	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04144//Endocytosis;ko04666//Fc gamma R-mediated phagocytosis	K12562;K12562	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0030424//axon;GO:0030425//dendrite;GO:0031674//I band;GO:0031982//vesicle;GO:0033268//node of Ranvier;GO:0043194//axon initial segment;GO:0043196//varicosity;GO:0043229//intracellular organelle;GO:0043679//axon terminus;GO:0044300//cerebellar mossy fiber;GO:0045202//synapse;GO:0060987//lipid tube;GO:0090571//RNA polymerase II transcription repressor complex;GO:0098850//extrinsic component of synaptic vesicle membrane;GO:0098978//glutamatergic synapse	GO:0002020//protease binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0030276//clathrin binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0048156//tau protein binding;GO:0051015//actin filament binding;GO:0051020//GTPase binding;GO:0051087//chaperone binding;GO:0070063//RNA polymerase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006897//endocytosis;GO:0006997//nucleus organization;GO:0007010//cytoskeleton organization;GO:0008333//endosome to lysosome transport;GO:0010564//regulation of cell cycle process;GO:0030100//regulation of endocytosis;GO:0030154//cell differentiation;GO:0030838//positive regulation of actin filament polymerization;GO:0033292//T-tubule organization;GO:0042692//muscle cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045664//regulation of neuron differentiation;GO:0045807//positive regulation of endocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0048711//positive regulation of astrocyte differentiation;GO:0051647//nucleus localization;GO:0060988//lipid tube assembly;GO:0086091//regulation of heart rate by cardiac conduction;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1902430//negative regulation of amyloid-beta formation;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1903946//negative regulation of ventricular cardiac muscle cell action potential;GO:1904878//negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	--
ENSG00000136718	19.922	26.412	23.906	29.663	28.253	21.978	604	750	528	680	729	526	IMP4	IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14561	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030684//preribosome;GO:0032040//small-subunit processome;GO:0034457//Mpp10 complex	GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0030515//snoRNA binding;GO:0042134//rRNA primary transcript binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000136720	12.353	12.823	13.247	15.212	16.58	16.491	1082	1129	857	987	1227	1051	HS6ST1	heparan sulfate 6-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5201]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02514	GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0017095//heparan sulfate 6-O-sulfotransferase activity	"GO:0001525//angiogenesis;GO:0006024//glycosaminoglycan biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:0048286//lung alveolus development;GO:0048666//neuron development;GO:0060716//labyrinthine layer blood vessel development"	--
ENSG00000136731	13.972	13.789	12.995	8.394	10.763	11.102	2130	2230	1513	1102	1499	1268	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15663]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K11718	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0032991//protein-containing complex;GO:0044322//endoplasmic reticulum quality control compartment;GO:0070062//extracellular exosome	GO:0003980//UDP-glucose:glycoprotein glucosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0051082//unfolded protein binding	GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0051084//'de novo' posttranslational protein folding;GO:0071712//ER-associated misfolded protein catabolic process;GO:0097359//UDP-glucosylation;GO:1904380//endoplasmic reticulum mannose trimming	--
ENSG00000136732	11.319	13.758	12.038	16.702	10.538	9.729	239	292	188	261	188	149	GYPC	glycophorin C (Gerbich blood group) [Source:HGNC Symbol;Acc:HGNC:4704]	Human Diseases	Infectious disease: parasitic	ko05144//Malaria	K06576	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030863//cortical cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000136738	41.352	32.015	38.334	31.812	33.924	41.008	2841	2494	2037	1836	2053	2217	STAM	signal transducing adaptor molecule [Source:HGNC Symbol;Acc:HGNC:11357]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04630//JAK-STAT signaling pathway	K04705;K04705	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0033565//ESCRT-0 complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding	GO:0007165//signal transduction;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:1903543//positive regulation of exosomal secretion;GO:1903551//regulation of extracellular exosome assembly	--
ENSG00000136750	0.009	0	0	0.057	0	0	1	0	0	2	0	0	GAD2	glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]	Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nervous system;Endocrine and metabolic disease;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko04727//GABAergic synapse;ko04940//Type I diabetes mellitus;ko00250//Alanine, aspartate and glutamate metabolism;ko00410//beta-Alanine metabolism;ko00650//Butanoate metabolism;ko00430//Taurine and hypotaurine metabolism"	K01580;K01580;K01580;K01580;K01580;K01580;K01580	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0060077//inhibitory synapse;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	GO:0003824//catalytic activity;GO:0004351//glutamate decarboxylase activity;GO:0005515//protein binding;GO:0016595//glutamate binding;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0044877//protein-containing complex binding	GO:0006540//glutamate decarboxylation to succinate;GO:0007268//chemical synaptic transmission;GO:0009410//response to xenobiotic stimulus;GO:0019752//carboxylic acid metabolic process;GO:0042136//neurotransmitter biosynthetic process	--
ENSG00000136754	31.828	31.098	30.314	31.934	31.139	36.081	2315	2271	1625	1719	1909	1908	ABI1	abl interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection	K23649;K23649	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030426//growth cone;GO:0031209//SCAR complex;GO:0031252//cell leading edge;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0017124//SH3 domain binding;GO:0030296//protein tyrosine kinase activator activity;GO:0035591//signaling adaptor activity;GO:0045296//cadherin binding	GO:0001756//somitogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008154//actin polymerization or depolymerization;GO:0008285//negative regulation of cell population proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035855//megakaryocyte development;GO:0048813//dendrite morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0072673//lamellipodium morphogenesis	--
ENSG00000136758	45.092	40.947	38.863	33.908	36.782	37.923	3560.86	3249.42	2277.31	2059.16	2381.73	2307.53	YME1L1	YME1 like 1 ATPase [Source:HGNC Symbol;Acc:HGNC:12843]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0004176//ATP-dependent peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0007005//mitochondrion organization;GO:0008283//cell population proliferation;GO:0034214//protein hexamerization;GO:0034982//mitochondrial protein processing;GO:0035694//mitochondrial protein catabolic process;GO:0043066//negative regulation of apoptotic process	--
ENSG00000136770	20.044	18.463	17.065	12.459	14.605	15.492	865	803	549	402	533	491	DNAJC1	DnaJ heat shock protein family (Hsp40) member C1 [Source:HGNC Symbol;Acc:HGNC:20090]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09521	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0001671//ATPase activator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0051087//chaperone binding	GO:0006417//regulation of translation;GO:0006457//protein folding;GO:0045861//negative regulation of proteolysis;GO:0050708//regulation of protein secretion	MYB
ENSG00000136783	15.707	13.574	13.806	14.402	13.045	13.892	533	463	346	362	374	343	NIPSNAP3A	nipsnap homolog 3A [Source:HGNC Symbol;Acc:HGNC:23619]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000136802	56.317	57.22	48.75	36.195	42.91	40.919	5071	5175	3239	2417	3265	2683	LRRC8A	leucine rich repeat containing 8 VRAC subunit A [Source:HGNC Symbol;Acc:HGNC:19027]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034702//ion channel complex;GO:1905103//integral component of lysosomal membrane	GO:0005225//volume-sensitive anion channel activity;GO:0005253//anion channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140360//cyclic-GMP-AMP transmembrane transporter activity	GO:0001678//cellular glucose homeostasis;GO:0002329//pre-B cell differentiation;GO:0006811//ion transport;GO:0006820//anion transport;GO:0006884//cell volume homeostasis;GO:0006970//response to osmotic stress;GO:0007283//spermatogenesis;GO:0015698//inorganic anion transport;GO:0015734//taurine transport;GO:0015810//aspartate transmembrane transport;GO:0030154//cell differentiation;GO:0032024//positive regulation of insulin secretion;GO:0034214//protein hexamerization;GO:0045663//positive regulation of myoblast differentiation;GO:0098656//anion transmembrane transport;GO:0140361//cyclic-GMP-AMP transmembrane import across plasma membrane;GO:1902476//chloride transmembrane transport	--
ENSG00000136807	13.507	16.205	17.1	16.238	16.079	16.395	639	734	594	569	630	544	CDK9	cyclin dependent kinase 9 [Source:HGNC Symbol;Acc:HGNC:1780]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K02211	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0008023//transcription elongation factor complex;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0016020//membrane;GO:0016592//mediator complex;GO:0016605//PML body;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070691//P-TEFb complex	GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017069//snRNA binding;GO:0019901//protein kinase binding;GO:0097322//7SK snRNA binding;GO:0106310//protein serine kinase activity	GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0016310//phosphorylation;GO:0031056//regulation of histone modification;GO:0031297//replication fork processing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033129//positive regulation of histone phosphorylation;GO:0043923//positive regulation by host of viral transcription;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051147//regulation of muscle cell differentiation;GO:0051726//regulation of cell cycle;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:0071345//cellular response to cytokine stimulus;GO:0120187//positive regulation of protein localization to chromatin;GO:1900364//negative regulation of mRNA polyadenylation;GO:1903654//phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter;GO:1903655//phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter;GO:1903839//positive regulation of mRNA 3'-UTR binding;GO:2001168//positive regulation of histone H2B ubiquitination	--
ENSG00000136810	20.083	22.974	23.737	24.109	18.66	20.319	307	353	268	273	241	226	TXN	thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial;Immune system;Cardiovascular disease	ko05012//Parkinson disease;ko05132//Salmonella infection;ko04621//NOD-like receptor signaling pathway;ko05418//Fluid shear stress and atherosclerosis	K03671;K03671;K03671;K03671	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0004791//thioredoxin-disulfide reductase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0042803//protein homodimerization activity;GO:0047134//protein-disulfide reductase (NAD(P)) activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0009314//response to radiation;GO:0032148//activation of protein kinase B activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043388//positive regulation of DNA binding;GO:0045454//cell redox homeostasis;GO:0046826//negative regulation of protein export from nucleus;GO:0051897//positive regulation of protein kinase B signaling;GO:0071731//response to nitric oxide;GO:0098869//cellular oxidant detoxification;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:2000170//positive regulation of peptidyl-cysteine S-nitrosylation	--
ENSG00000136811	11.174	11.634	10.752	9.591	9.77	7.775	675	718	479	436	493	326	ODF2	outer dense fiber of sperm tails 2 [Source:HGNC Symbol;Acc:HGNC:8114]	-	-	-	-	GO:0000922//spindle pole;GO:0001520//outer dense fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097539//ciliary transition fiber;GO:0120103//centriolar subdistal appendage	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008104//protein localization;GO:0010457//centriole-centriole cohesion;GO:0030154//cell differentiation;GO:0044782//cilium organization;GO:1902017//regulation of cilium assembly	--
ENSG00000136813	19.966	19.68	17.385	15.527	16.624	15.223	2582	2534	1782	1503	1824	1560	ECPAS	Ecm29 proteasome adaptor and scaffold [Source:HGNC Symbol;Acc:HGNC:29020]	-	-	-	-	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0060090//molecular adaptor activity;GO:0070628//proteasome binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043248//proteasome assembly	--
ENSG00000136816	8.399	7.042	8.154	7.488	7.795	7.865	477	402	342	315	374	325	TOR1B	torsin family 1 member B [Source:HGNC Symbol;Acc:HGNC:11995]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding;GO:0042802//identical protein binding	GO:0006986//response to unfolded protein;GO:0007029//endoplasmic reticulum organization;GO:0034504//protein localization to nucleus;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071763//nuclear membrane organization	--
ENSG00000136819	17.243	19.747	17.965	14.613	16.404	16.796	642	739	494	403	516	455	C9orf78	chromosome 9 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:24932]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000136824	3.335	2.316	1.23	0.969	1.491	1.643	348	252	107	81	131	134	SMC2	structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0045132//meiotic chromosome segregation;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051383//kinetochore organization;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000136826	0.115	0.131	0.103	0.1	0.091	0.158	7	8	4	3	4	7	KLF4	Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348]	Human Diseases;Cellular Processes	Cancer: overview;Cellular community - eukaryotes	ko05207//Chemical carcinogenesis - receptor activation;ko04550//Signaling pathways regulating pluripotency of stem cells	K17846;K17846	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001010//RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002357//defense response to tumor cell;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007500//mesodermal cell fate determination;GO:0008285//negative regulation of cell population proliferation;GO:0009913//epidermal cell differentiation;GO:0010033//response to organic substance;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016525//negative regulation of angiogenesis;GO:0019827//stem cell population maintenance;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0031077//post-embryonic camera-type eye development;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032526//response to retinoic acid;GO:0032717//negative regulation of interleukin-8 production;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0035166//post-embryonic hemopoiesis;GO:0042127//regulation of cell population proliferation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045444//fat cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048679//regulation of axon regeneration;GO:0048730//epidermis morphogenesis;GO:0050728//negative regulation of inflammatory response;GO:0051247//positive regulation of protein metabolic process;GO:0051973//positive regulation of telomerase activity;GO:0060070//canonical Wnt signaling pathway;GO:0060761//negative regulation of response to cytokine stimulus;GO:0071363//cellular response to growth factor stimulus;GO:0071499//cellular response to laminar fluid shear stress;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0120222//regulation of blastocyst development;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904798//positive regulation of core promoter binding;GO:1904998//negative regulation of leukocyte adhesion to arterial endothelial cell;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production"	zf-C2H2
ENSG00000136827	21.489	25.382	23.745	22.035	20.182	22.704	931	1107	759	710	741	718	TOR1A	torsin family 1 member A [Source:HGNC Symbol;Acc:HGNC:3098]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030426//growth cone;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding;GO:0140662//ATP-dependent protein folding chaperone	"GO:0000338//protein deneddylation;GO:0006979//response to oxidative stress;GO:0006996//organelle organization;GO:0006998//nuclear envelope organization;GO:0007155//cell adhesion;GO:0031175//neuron projection development;GO:0034504//protein localization to nucleus;GO:0044319//wound healing, spreading of cells;GO:0045104//intermediate filament cytoskeleton organization;GO:0048489//synaptic vesicle transport;GO:0048499//synaptic vesicle membrane organization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0061077//chaperone-mediated protein folding;GO:0071712//ER-associated misfolded protein catabolic process;GO:0071763//nuclear membrane organization;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:2000008//regulation of protein localization to cell surface"	--
ENSG00000136828	5.65	7.622	6.027	7.659	7.638	6.595	526	534	371	373	471	356	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1 [Source:HGNC Symbol;Acc:HGNC:16851]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0032485//regulation of Ral protein signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000136830	26.955	29.197	26.578	30.267	30.429	27.634	2204	2397	1605	1821	2102	1644	NIBAN2	niban apoptosis regulator 2 [Source:HGNC Symbol;Acc:HGNC:25282]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0045296//cadherin binding	"GO:0007411//axon guidance;GO:0008285//negative regulation of cell population proliferation;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032274//gonadotropin secretion;GO:0040019//positive regulation of embryonic development;GO:0043066//negative regulation of apoptotic process;GO:0044029//hypomethylation of CpG island;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048743//positive regulation of skeletal muscle fiber development;GO:2000279//negative regulation of DNA biosynthetic process;GO:2000679//positive regulation of transcription regulatory region DNA binding"	--
ENSG00000136834	0	0	0	0	0	0	0	0	0	0	0	0	OR1J1	olfactory receptor family 1 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:8208]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000136839	0	0	0	0	0	0	0	0	0	0	0	0	OR13C9	olfactory receptor family 13 subfamily C member 9 [Source:HGNC Symbol;Acc:HGNC:15104]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000136840	11.141	12.528	12.247	11.618	12.577	9.618	362	417	300	296	376	238	ST6GALNAC4	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:17846]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03374;K03374;K03374	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047290//(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006664//glycolipid metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016266//O-glycan processing;GO:0019082//viral protein processing;GO:0097503//sialylation	--
ENSG00000136842	3.11	3.061	2.46	1.52	2.141	2.125	213.6	211.28	124.76	75.99	124.08	102.28	TMOD1	tropomodulin 1 [Source:HGNC Symbol;Acc:HGNC:11871]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0008180//COP9 signalosome;GO:0016020//membrane;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0030863//cortical cytoskeleton	GO:0003779//actin binding;GO:0005523//tropomyosin binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0008344//adult locomotory behavior;GO:0030239//myofibril assembly;GO:0051694//pointed-end actin filament capping;GO:0070307//lens fiber cell development	--
ENSG00000136848	17.531	17.103	27.846	23.377	19.451	22.174	2008	2056	1595	1626	1910	1762	DAB2IP	DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294]	Cellular Processes;Environmental Information Processing	Cell growth and death;Signal transduction	ko04210//Apoptosis;ko04668//TNF signaling pathway	K19901;K19901	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044300//cerebellar mossy fiber;GO:0044301//climbing fiber;GO:1990032//parallel fiber;GO:1990597//AIP1-IRE1 complex	GO:0005096//GTPase activator activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035591//signaling adaptor activity;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0051721//protein phosphatase 2A binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0071889//14-3-3 protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006986//response to unfolded protein;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007252//I-kappaB phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010596//negative regulation of endothelial cell migration;GO:0010633//negative regulation of epithelial cell migration;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010976//positive regulation of neuron projection development;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016525//negative regulation of angiogenesis;GO:0021814//cell motility involved in cerebral cortex radial glia guided migration;GO:0021819//layer formation in cerebral cortex;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0034620//cellular response to unfolded protein;GO:0035148//tube formation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0038026//reelin-mediated signaling pathway;GO:0040008//regulation of growth;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0043407//negative regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity;GO:0044257//cellular protein catabolic process;GO:0045087//innate immune response;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048147//negative regulation of fibroblast proliferation;GO:0048812//neuron projection morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051726//regulation of cell cycle;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070317//negative regulation of G0 to G1 transition;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0072577//endothelial cell apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090129//positive regulation of synapse maturation;GO:1900006//positive regulation of dendrite development;GO:1900744//regulation of p38MAPK cascade;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1903363//negative regulation of cellular protein catabolic process;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:2001224//positive regulation of neuron migration;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000136854	13.234	15.271	12.876	14.234	14.108	11.976	996	1070	737	745	926	682	STXBP1	syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15292	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030141//secretory granule;GO:0030424//axon;GO:0031091//platelet alpha granule;GO:0032991//protein-containing complex;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0048787//presynaptic active zone membrane;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000149//SNARE binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0019905//syntaxin binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0047485//protein N-terminus binding	"GO:0002576//platelet degranulation;GO:0003006//developmental process involved in reproduction;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007269//neurotransmitter secretion;GO:0007274//neuromuscular synaptic transmission;GO:0007412//axon target recognition;GO:0010807//regulation of synaptic vesicle priming;GO:0015031//protein transport;GO:0016082//synaptic vesicle priming;GO:0016188//synaptic vesicle maturation;GO:0016192//vesicle-mediated transport;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031338//regulation of vesicle fusion;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0032355//response to estradiol;GO:0035493//SNARE complex assembly;GO:0035542//regulation of SNARE complex assembly;GO:0043306//positive regulation of mast cell degranulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0045921//positive regulation of exocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0050821//protein stabilization;GO:0060292//long-term synaptic depression;GO:0070527//platelet aggregation;GO:0071346//cellular response to interferon-gamma;GO:0072659//protein localization to plasma membrane;GO:0099525//presynaptic dense core vesicle exocytosis;GO:0106022//positive regulation of vesicle docking;GO:1903296//positive regulation of glutamate secretion, neurotransmission;GO:2000367//regulation of acrosomal vesicle exocytosis"	--
ENSG00000136856	8.382	8.153	7.736	7.991	7.592	5.438	315	285	244	242	264	167	SLC2A8	solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005353//fructose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005536//glucose binding;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0001666//response to hypoxia;GO:0005975//carbohydrate metabolic process;GO:0007141//male meiosis I;GO:0008286//insulin receptor signaling pathway;GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0015755//fructose transmembrane transport;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:1904659//glucose transmembrane transport	--
ENSG00000136859	41.608	41.587	33.558	30.757	32.021	38.067	2960	2973	1770	1627	1932	1978	ANGPTL2	angiopoietin like 2 [Source:HGNC Symbol;Acc:HGNC:490]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007275//multicellular organism development	--
ENSG00000136861	19.089	17.403	16.75	12.874	12.861	12.223	2316	2114	1527	1081	1293	1022	CDK5RAP2	CDK5 regulatory subunit associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18672]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000922//spindle pole;GO:0000931//gamma-tubulin large complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0035371//microtubule plus-end;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097431//mitotic spindle pole	GO:0000976//transcription cis-regulatory region binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0019901//protein kinase binding;GO:0043015//gamma-tubulin binding;GO:0044877//protein-containing complex binding	"GO:0000132//establishment of mitotic spindle orientation;GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0007059//chromosome segregation;GO:0007098//centrosome cycle;GO:0007099//centriole replication;GO:0007420//brain development;GO:0022008//neurogenesis;GO:0031023//microtubule organizing center organization;GO:0031116//positive regulation of microtubule polymerization;GO:0045664//regulation of neuron differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046600//negative regulation of centriole replication;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint"	--
ENSG00000136866	2.017	1.672	2.334	1.178	1.381	1.502	125	116	106	60	76	66	ZFP37	ZFP37 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:12863]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000136867	1.431	1.405	1.13	1.233	1.497	1.426	51.14	50.46	29.82	32.65	45.2	37.07	SLC31A2	solute carrier family 31 member 2 [Source:HGNC Symbol;Acc:HGNC:11017]	-	-	-	-	GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0005375//copper ion transmembrane transporter activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0035434//copper ion transmembrane transport;GO:1902311//regulation of copper ion transmembrane transport	--
ENSG00000136868	18.882	20.064	19.753	16.825	17.172	18.631	1865	1992	1441	1231	1433	1339	SLC31A1	solute carrier family 31 member 1 [Source:HGNC Symbol;Acc:HGNC:11016]	Human Diseases;Organismal Systems	Drug resistance: antineoplastic;Digestive system	ko01524//Platinum drug resistance;ko04978//Mineral absorption	K14686;K14686	GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0005375//copper ion transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0015677//copper ion import;GO:0035434//copper ion transmembrane transport	--
ENSG00000136869	0.281	0.424	0.119	0.131	0.145	0.212	32	39	13	10	15	15	TLR4	toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Cell growth and death;Infectious disease: viral;Immune disease;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Infectious disease: bacterial;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04217//Necroptosis;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04066//HIF-1 signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko05144//Malaria	K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160	GO:0001726//ruffle;GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0046696//lipopolysaccharide receptor complex;GO:0048471//perinuclear region of cytoplasm	"GO:0001530//lipopolysaccharide binding;GO:0001540//amyloid-beta binding;GO:0001875//lipopolysaccharide immune receptor activity;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0002218//activation of innate immune response;GO:0002224//toll-like receptor signaling pathway;GO:0002246//wound healing involved in inflammatory response;GO:0002322//B cell proliferation involved in immune response;GO:0002376//immune system process;GO:0002537//nitric oxide production involved in inflammatory response;GO:0002730//regulation of dendritic cell cytokine production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007252//I-kappaB phosphorylation;GO:0009617//response to bacterium;GO:0010572//positive regulation of platelet activation;GO:0010628//positive regulation of gene expression;GO:0014002//astrocyte development;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016046//detection of fungus;GO:0030890//positive regulation of B cell proliferation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032497//detection of lipopolysaccharide;GO:0032689//negative regulation of interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0032707//negative regulation of interleukin-23 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032722//positive regulation of chemokine production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032732//positive regulation of interleukin-1 production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042088//T-helper 1 type immune response;GO:0042116//macrophage activation;GO:0042742//defense response to bacterium;GO:0043032//positive regulation of macrophage activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045671//negative regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060729//intestinal epithelial structure maintenance;GO:0060907//positive regulation of macrophage cytokine production;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070430//positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071260//cellular response to mechanical stimulus;GO:0071346//cellular response to interferon-gamma;GO:0120163//negative regulation of cold-induced thermogenesis;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903223//positive regulation of oxidative stress-induced neuron death;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1903974//positive regulation of cellular response to macrophage colony-stimulating factor stimulus;GO:1904466//positive regulation of matrix metallopeptidase secretion;GO:1904646//cellular response to amyloid-beta;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000136870	9.537	8.649	7.981	7.087	7.545	8.109	614	535	384	343	414	384	ZNF189	zinc finger protein 189 [Source:HGNC Symbol;Acc:HGNC:12980]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000136872	0.02	0	0	0	0	0.027	1	0	0	0	0	1	ALDOB	"aldolase, fructose-bisphosphate B [Source:HGNC Symbol;Acc:HGNC:417]"	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K01623;K01623;K01623;K01623;K01623;K01623;K01623	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004332//fructose-bisphosphate aldolase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0051117//ATPase binding;GO:0061609//fructose-1-phosphate aldolase activity;GO:0070061//fructose binding	"GO:0006000//fructose metabolic process;GO:0006096//glycolytic process;GO:0006116//NADH oxidation;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0032781//positive regulation of ATPase activity;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly"	--
ENSG00000136874	7.339	5.112	5.688	4.642	5.053	6.446	955	718	517	468	580	576	STX17	syntaxin 17 [Source:HGNC Symbol;Acc:HGNC:11432]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04140//Autophagy - animal;ko04130//SNARE interactions in vesicular transport	K08491;K08491	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030868//smooth endoplasmic reticulum membrane;GO:0030897//HOPS complex;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0016192//vesicle-mediated transport;GO:0016240//autophagosome membrane docking;GO:0034497//protein localization to phagophore assembly site;GO:0048278//vesicle docking;GO:0097111//endoplasmic reticulum-Golgi intermediate compartment organization;GO:0097352//autophagosome maturation	--
ENSG00000136875	9.119	9.018	8.315	8.101	8.305	8.337	570	571	386	375	439	385	PRPF4	pre-mRNA processing factor 4 [Source:HGNC Symbol;Acc:HGNC:17349]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12662	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071001//U4/U6 snRNP;GO:0071005//U2-type precatalytic spliceosome;GO:0097525//spliceosomal snRNP complex;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0030621//U4 snRNA binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000136877	14.423	13.946	14.287	20.66	13.692	14.949	545	596	487	597	517	469	FPGS	folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko01523//Antifolate resistance;ko00790//Folate biosynthesis	K01930;K01930;K01930	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004326//tetrahydrofolylpolyglutamate synthase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016881//acid-amino acid ligase activity;GO:0046872//metal ion binding	GO:0001889//liver development;GO:0006139//nucleobase-containing compound metabolic process;GO:0006536//glutamate metabolic process;GO:0006730//one-carbon metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0007420//brain development;GO:0008283//cell population proliferation;GO:0009058//biosynthetic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0031100//animal organ regeneration;GO:0046655//folic acid metabolic process;GO:0046901//tetrahydrofolylpolyglutamate biosynthetic process	--
ENSG00000136878	7.433	7.804	7.809	7.058	7.443	7.991	668	706	517	467	565	524	USP20	ubiquitin specific peptidase 20 [Source:HGNC Symbol;Acc:HGNC:12619]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm	GO:0001664//G protein-coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006897//endocytosis;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0016579//protein deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000136881	0	0	0	0	0	0	0	0	0	0	0	0	BAAT	bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932]	Metabolism;Organismal Systems;Cellular Processes;Metabolism;Metabolism;Metabolism	Global and overview maps;Digestive system;Transport and catabolism;Lipid metabolism;Metabolism of other amino acids;Lipid metabolism	ko01100//Metabolic pathways;ko04976//Bile secretion;ko04146//Peroxisome;ko01040//Biosynthesis of unsaturated fatty acids;ko00430//Taurine and hypotaurine metabolism;ko00120//Primary bile acid biosynthesis	K00659;K00659;K00659;K00659;K00659;K00659	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0033882//choloyl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0047963//glycine N-choloyltransferase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0052816//long-chain acyl-CoA hydrolase activity;GO:0052817//very long chain acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0001889//liver development;GO:0002152//bile acid conjugation;GO:0006544//glycine metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0019530//taurine metabolic process;GO:0031100//animal organ regeneration	--
ENSG00000136883	0.351	0.437	0.476	0.342	0.338	0.417	16	15	16	9	13	5	KIF12	kinesin family member 12 [Source:HGNC Symbol;Acc:HGNC:21495]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding	GO:0007018//microtubule-based movement	--
ENSG00000136888	83.996	89.706	84.542	71.527	76.73	93.554	2272	2326	1812	1631	1662	1831	ATP6V1G1	ATPase H+ transporting V1 subunit G1 [Source:HGNC Symbol;Acc:HGNC:864]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0016241//regulation of macroautophagy;GO:0036295//cellular response to increased oxygen levels;GO:1902600//proton transmembrane transport	--
ENSG00000136891	6.325	6.235	6.47	5.33	6.101	6.826	390	400	305	252	329	317	TEX10	testis expressed 10 [Source:HGNC Symbol;Acc:HGNC:25988]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0071339//MLL1 complex	GO:0005515//protein binding	-	--
ENSG00000136895	9.617	9.587	7.279	7.911	8.734	8.483	347	368	285	240	312	214	GARNL3	GTPase activating Rap/RanGAP domain like 3 [Source:HGNC Symbol;Acc:HGNC:25425]	-	-	-	-	GO:0005737//cytoplasm	GO:0005096//GTPase activator activity	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000136897	3.859	3.566	4.324	3.863	3.455	3.516	267	248	221	198	202	177	MRPL50	mitochondrial ribosomal protein L50 [Source:HGNC Symbol;Acc:HGNC:16654]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome	-	GO:0032543//mitochondrial translation	--
ENSG00000136908	24.423	24.719	25.553	34.346	28.094	20.706	462	470	357	481	449	285	DPM2	"dolichyl-phosphate mannosyltransferase subunit 2, regulatory [Source:HGNC Symbol;Acc:HGNC:3006]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K09658;K09658;K09658	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033185//dolichol-phosphate-mannose synthase complex	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030234//enzyme regulator activity	GO:0006486//protein glycosylation;GO:0006506//GPI anchor biosynthetic process;GO:0019348//dolichol metabolic process;GO:0031647//regulation of protein stability;GO:0035269//protein O-linked mannosylation;GO:0050790//regulation of catalytic activity	--
ENSG00000136918	0.444	1.274	0.619	0.051	0.135	0	12	34	12	1	3	0	WDR38	WD repeat domain 38 [Source:HGNC Symbol;Acc:HGNC:23745]	-	-	-	-	-	GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000136925	9.411	8.813	9.603	8.417	7.966	7.884	799.4	749.72	592.24	526.01	557.92	481.72	TSTD2	thiosulfate sulfurtransferase like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30087]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000136928	0.245	0.157	0.154	0.13	0.176	0.072	28	18	13	11	17	6	GABBR2	gamma-aminobutyric acid type B receptor subunit 2 [Source:HGNC Symbol;Acc:HGNC:4507]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Substance dependence;Nervous system;Sensory system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04915//Estrogen signaling pathway;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko04929//GnRH secretion	K04615;K04615;K04615;K04615;K04615;K04615;K04615	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0038039//G protein-coupled receptor heterodimeric complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0110165//cellular anatomical entity;GO:1902710//GABA receptor complex;GO:1902712//G protein-coupled GABA receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004965//G protein-coupled GABA receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0051932//synaptic transmission, GABAergic;GO:0150099//neuron-glial cell signaling"	--
ENSG00000136929	0	0	0	0	0	0	0	0	0	0	0	0	HEMGN	hemogen [Source:HGNC Symbol;Acc:HGNC:17509]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0045667//regulation of osteoblast differentiation	--
ENSG00000136930	51.592	61.418	61.761	58.141	54.745	58.382	1053	1260	931	879	944	867	PSMB7	proteasome 20S subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:9544]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02739;K02739;K02739;K02739;K02739;K02739;K02739;K02739	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0016604//nuclear body;GO:0019774//proteasome core complex, beta-subunit complex;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen"	GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000136931	0.031	0.016	0	0.066	0	0	2	1	0	3	0	0	NR5A1	nuclear receptor subfamily 5 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7983]	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Endocrine system	ko04934//Cushing syndrome;ko04927//Cortisol synthesis and secretion	K08560;K08560	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001553//luteinization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007530//sex determination;GO:0007538//primary sex determination;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0009888//tissue development;GO:0010259//multicellular organism aging;GO:0010628//positive regulation of gene expression;GO:0022414//reproductive process;GO:0030154//cell differentiation;GO:0030238//male sex determination;GO:0030325//adrenal gland development;GO:0030522//intracellular receptor signaling pathway;GO:0042445//hormone metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050810//regulation of steroid biosynthetic process;GO:0051457//maintenance of protein location in nucleus;GO:2000020//positive regulation of male gonad development;GO:2000195//negative regulation of female gonad development"	SF-like
ENSG00000136932	4.576	5.943	5.763	5.521	4.863	7.172	148	187	137	133	129	170	TRMO	tRNA methyltransferase O [Source:HGNC Symbol;Acc:HGNC:30967]	-	-	-	-	-	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016430//tRNA (adenine-N6-)-methyltransferase activity;GO:0016740//transferase activity;GO:0089715//tRNA m6t6A37 methyltransferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000136933	7.51	7.521	6.896	8.023	6.814	7.632	236	239	162	188	180	180	RABEPK	Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	GO:0006898//receptor-mediated endocytosis;GO:0006904//vesicle docking involved in exocytosis	--
ENSG00000136935	5.407	5.789	4.859	3.87	4.535	4.619	547	565	363	290	386	340	GOLGA1	golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000136936	5.408	5.605	5.358	4.742	4.816	6.101	158	164	116	103	119	130	XPA	"XPA, DNA damage recognition and repair factor [Source:HGNC Symbol;Acc:HGNC:12814]"	Human Diseases;Genetic Information Processing	Drug resistance: antineoplastic;Replication and repair	ko01524//Platinum drug resistance;ko03420//Nucleotide excision repair	K10847;K10847	GO:0000110//nucleotide-excision repair factor 1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0045171//intercellular bridge	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006289//nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009650//UV protection;GO:0033683//nucleotide-excision repair, DNA incision;GO:0034504//protein localization to nucleus;GO:0070914//UV-damage excision repair;GO:1901255//nucleotide-excision repair involved in interstrand cross-link repair"	Others
ENSG00000136937	11.034	9.358	8.701	7.825	9.243	9.357	1004	901	642	570	715	583	NCBP1	nuclear cap binding protein subunit 1 [Source:HGNC Symbol;Acc:HGNC:7658]	Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Neurodegenerative disease;Transcription;Translation;Translation	ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12882;K12882;K12882;K12882	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0005846//nuclear cap binding complex;GO:0034518//RNA cap binding complex;GO:1990904//ribonucleoprotein complex	GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0002191//cap-dependent translational initiation;GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0006401//RNA catabolic process;GO:0006406//mRNA export from nucleus;GO:0006408//snRNA export from nucleus;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0008334//histone mRNA metabolic process;GO:0008380//RNA splicing;GO:0016070//RNA metabolic process;GO:0016246//RNA interference;GO:0030307//positive regulation of cell growth;GO:0031047//gene silencing by RNA;GO:0031053//primary miRNA processing;GO:0031124//mRNA 3'-end processing;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0035195//gene silencing by miRNA;GO:0042789//mRNA transcription by RNA polymerase II;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:0051607//defense response to virus;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:1905216//positive regulation of RNA binding"	--
ENSG00000136938	47.236	47.544	46.746	44.678	43.328	39.05	1453	1470	1062	1018	1126	874	ANP32B	acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042393//histone binding;GO:0070063//RNA polymerase binding	GO:0001944//vasculature development;GO:0006334//nucleosome assembly;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0021591//ventricular system development;GO:0042981//regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0046827//positive regulation of protein export from nucleus;GO:0048839//inner ear development;GO:0060021//roof of mouth development	--
ENSG00000136939	0	0	0	0	0	0	0	0	0	0	0	0	OR1L4	olfactory receptor family 1 subfamily L member 4 [Source:HGNC Symbol;Acc:HGNC:8216]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000136940	5.858	6.408	7.192	5.134	5.093	6.28	349	393	319	238	259	266	PDCL	phosducin like [Source:HGNC Symbol;Acc:HGNC:8770]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0030030//cell projection organization;GO:0045880//positive regulation of smoothened signaling pathway;GO:0050896//response to stimulus;GO:1902605//heterotrimeric G-protein complex assembly	--
ENSG00000136942	179.603	185.37	190.777	192.091	167.385	155.536	1684	1747	1321	1334	1326	1061	RPL35	ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:10344]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02918;K02918	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006412//translation"	--
ENSG00000136943	370.464	391.807	409.951	318.902	273.426	302.907	12349	13160	10163	7837	7749	7377	CTSV	cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K01375;K01375	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0043202//lysosomal lumen	GO:0004197//cysteine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006955//immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0022617//extracellular matrix disassembly;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000136944	0	0	0	0	0.036	0	0	0	0	0	4	0	LMX1B	LIM homeobox transcription factor 1 beta [Source:HGNC Symbol;Acc:HGNC:6654]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009953//dorsal/ventral pattern formation;GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071542//dopaminergic neuron differentiation"	Homeobox
ENSG00000136950	8.819	9.29	10.222	9.746	9.308	10.989	287	287	239	214	253	254	ARPC5L	actin related protein 2/3 complex subunit 5 like [Source:HGNC Symbol;Acc:HGNC:23366]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05754;K05754;K05754;K05754;K05754;K05754;K05754;K05754;K05754	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0008150//biological_process;GO:0016477//cell migration;GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation	--
ENSG00000136960	675.926	663.637	797.86	708.261	716.08	936.974	38549	37905	33497	29788	34415	38505	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K01122;K01122	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0004528//phosphodiesterase I activity;GO:0004551//nucleotide diphosphatase activity;GO:0004622//lysophospholipase activity;GO:0005044//scavenger receptor activity;GO:0005509//calcium ion binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0030247//polysaccharide binding;GO:0046872//metal ion binding;GO:0047391//alkylglycerophosphoethanolamine phosphodiesterase activity"	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0009395//phospholipid catabolic process;GO:0010634//positive regulation of epithelial cell migration;GO:0016042//lipid catabolic process;GO:0030149//sphingolipid catabolic process;GO:0030334//regulation of cell migration;GO:0034638//phosphatidylcholine catabolic process;GO:0044238//primary metabolic process;GO:0045765//regulation of angiogenesis;GO:0048870//cell motility;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071704//organic substance metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:2000394//positive regulation of lamellipodium morphogenesis	--
ENSG00000136982	2.325	2.379	2.406	1.51	1.168	1.206	106	109	81	51	45	40	DSCC1	DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031390//Ctf18 RFC-like complex"	GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0017116//single-stranded DNA helicase activity	GO:0006260//DNA replication;GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0032508//DNA duplex unwinding;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0034421//post-translational protein acetylation;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000136986	26.91	28.051	29.871	26.169	25.477	29.023	1780.93	1879.02	1321.45	1279.03	1434.46	1407.35	DERL1	derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum	K11519;K11519;K11519	GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0036502//Derlin-1-VIMP complex;GO:0036513//Derlin-1 retrotranslocation complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0002020//protease binding;GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0038023//signaling receptor activity;GO:0042288//MHC class I protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0051117//ATPase binding;GO:0051787//misfolded protein binding;GO:1990381//ubiquitin-specific protease binding	"GO:0006950//response to stress;GO:0006986//response to unfolded protein;GO:0015031//protein transport;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031398//positive regulation of protein ubiquitination;GO:0031648//protein destabilization;GO:0032092//positive regulation of protein binding;GO:0034620//cellular response to unfolded protein;GO:0036503//ERAD pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045184//establishment of protein localization;GO:0071712//ER-associated misfolded protein catabolic process"	--
ENSG00000136997	6.58	7.426	5.385	7.812	7.059	6.27	304	337	190	225	258	217	MYC	"MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]"	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: overview;Signal transduction;Signal transduction;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cell growth and death;Endocrine system;Signal transduction;Cancer: specific types;Cancer: specific types;Signal transduction;Cancer: specific types;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05132//Salmonella infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko05220//Chronic myeloid leukemia;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko05213//Endometrial cancer;ko05219//Bladder cancer;ko05216//Thyroid cancer	K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377;K04377	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0044195//nucleoplasmic reticulum;GO:0071943//Myc-Max complex;GO:0090571//RNA polymerase II transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001046//core promoter sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0071074//eukaryotic initiation factor eIF2 binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0006112//energy reserve metabolic process;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006879//cellular iron ion homeostasis;GO:0006974//cellular response to DNA damage stimulus;GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010332//response to gamma radiation;GO:0010468//regulation of gene expression;GO:0010564//regulation of cell cycle process;GO:0010628//positive regulation of gene expression;GO:0015671//oxygen transport;GO:0032204//regulation of telomere maintenance;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0032986//protein-DNA complex disassembly;GO:0034644//cellular response to UV;GO:0043066//negative regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044346//fibroblast apoptotic process;GO:0045656//negative regulation of monocyte differentiation;GO:0045727//positive regulation of translation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0048147//negative regulation of fibroblast proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051276//chromosome organization;GO:0051782//negative regulation of cell division;GO:0051973//positive regulation of telomerase activity;GO:0070371//ERK1 and ERK2 cascade;GO:0070848//response to growth factor;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0090096//positive regulation of metanephric cap mesenchymal cell proliferation;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904672//regulation of somatic stem cell population maintenance;GO:1905643//positive regulation of DNA methylation;GO:2000573//positive regulation of DNA biosynthetic process;GO:2001022//positive regulation of response to DNA damage stimulus"	bHLH
ENSG00000136999	6.205	7.108	5.645	4.175	5.676	5.3	317	365	213	158	245	197	CCN3	cellular communication network factor 3 [Source:HGNC Symbol;Acc:HGNC:7885]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005921//gap junction;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031012//extracellular matrix;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix	GO:0005112//Notch binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding	GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010468//regulation of gene expression;GO:0010761//fibroblast migration;GO:0010832//negative regulation of myotube differentiation;GO:0014909//smooth muscle cell migration;GO:0030308//negative regulation of cell growth;GO:0033627//cell adhesion mediated by integrin;GO:0035767//endothelial cell chemotaxis;GO:0044342//type B pancreatic cell proliferation;GO:0045747//positive regulation of Notch signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0048659//smooth muscle cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0050793//regulation of developmental process;GO:0060326//cell chemotaxis;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0060548//negative regulation of cell death;GO:0061484//hematopoietic stem cell homeostasis;GO:0071603//endothelial cell-cell adhesion;GO:0090027//negative regulation of monocyte chemotaxis;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1902731//negative regulation of chondrocyte proliferation;GO:1904057//negative regulation of sensory perception of pain;GO:1990523//bone regeneration	--
ENSG00000137033	15.17	13.267	15.036	6.69	6.992	5.133	843	734	617	276	329	208	IL33	interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Cell growth and death;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05164//Influenza A;ko04217//Necroptosis;ko04623//Cytosolic DNA-sensing pathway	K12967;K12967;K12967;K12967	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0002112//interleukin-33 receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001819//positive regulation of cytokine production;GO:0002281//macrophage activation involved in immune response;GO:0002282//microglial cell activation involved in immune response;GO:0002638//negative regulation of immunoglobulin production;GO:0002639//positive regulation of immunoglobulin production;GO:0002686//negative regulation of leukocyte migration;GO:0002826//negative regulation of T-helper 1 type immune response;GO:0002830//positive regulation of type 2 immune response;GO:0010186//positive regulation of cellular defense response;GO:0010628//positive regulation of gene expression;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032689//negative regulation of interferon-gamma production;GO:0032722//positive regulation of chemokine production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0038172//interleukin-33-mediated signaling pathway;GO:0042060//wound healing;GO:0043032//positive regulation of macrophage activation;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050729//positive regulation of inflammatory response;GO:0051607//defense response to virus;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051930//regulation of sensory perception of pain;GO:0061518//microglial cell proliferation;GO:0071260//cellular response to mechanical stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0120042//negative regulation of macrophage proliferation;GO:0150078//positive regulation of neuroinflammatory response;GO:0150142//positive regulation of CD86 production;GO:0150145//positive regulation of CD80 production	--
ENSG00000137038	13.918	15.389	12.678	14.973	13.174	12.195	709	788	477	565	567	452	DMAC1	distal membrane arm assembly component 1 [Source:HGNC Symbol;Acc:HGNC:30536]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000137040	9.679	7.727	8.124	6.664	7.506	7.6	904	718	539	471	536	488	RANBP6	RAN binding protein 6 [Source:HGNC Symbol;Acc:HGNC:9851]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0015031//protein transport	--
ENSG00000137054	6.634	6.775	6.198	6.571	6.306	5.037	255	262	176	187	205	141	POLR1E	RNA polymerase I subunit E [Source:HGNC Symbol;Acc:HGNC:17631]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K03005	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex	GO:0001179//RNA polymerase I general transcription initiation factor binding;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0001188//RNA polymerase I preinitiation complex assembly;GO:0006351//transcription, DNA-templated;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0042790//nucleolar large rRNA transcription by RNA polymerase I"	--
ENSG00000137055	12.36	11.469	11.619	11.272	11.316	10.977	827	736	545	490	578	469	PLAA	phospholipase A2 activating protein [Source:HGNC Symbol;Acc:HGNC:9043]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14018	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016005//phospholipase A2 activator activity;GO:0043130//ubiquitin binding	GO:0006644//phospholipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010992//ubiquitin recycling;GO:0016236//macroautophagy;GO:0032430//positive regulation of phospholipase A2 activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0071222//cellular response to lipopolysaccharide;GO:1900045//negative regulation of protein K63-linked ubiquitination;GO:1903423//positive regulation of synaptic vesicle recycling;GO:1903861//positive regulation of dendrite extension;GO:2001224//positive regulation of neuron migration	--
ENSG00000137070	8.915	9.677	9.12	9.117	8.279	8.043	308.72	339.54	236.51	221.51	232.52	199.75	IL11RA	interleukin 11 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5967]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05056;K05056;K05056	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0004921//interleukin-11 receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0019970//interleukin-11 binding	GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0032502//developmental process;GO:0038154//interleukin-11-mediated signaling pathway;GO:0060322//head development	--
ENSG00000137073	10.887	11.55	10.656	9.222	9.937	9.415	957	1020	675	599	740	556	UBAP2	ubiquitin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:14185]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0010468//regulation of gene expression	--
ENSG00000137074	9.146	10.069	7.554	9.714	11.435	6.472	296	364	201	271	322	181	APTX	aprataxin [Source:HGNC Symbol;Acc:HGNC:15984]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003725//double-stranded RNA binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008967//phosphoglycolate phosphatase activity;GO:0016787//hydrolase activity;GO:0030983//mismatched DNA binding;GO:0033699//DNA 5'-adenosine monophosphate hydrolase activity;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051219//phosphoprotein binding;GO:0120108//DNA-3'-diphospho-5'-guanosine diphosphatase;GO:1990165//single-strand break-containing DNA binding	GO:0000012//single strand break repair;GO:0006259//DNA metabolic process;GO:0006266//DNA ligation;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016311//dephosphorylation;GO:0031647//regulation of protein stability;GO:0042542//response to hydrogen peroxide;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000137075	13.32	12.579	13.269	12.146	13.427	13.713	1399	1325	1028	943	1187	1043	RNF38	ring finger protein 38 [Source:HGNC Symbol;Acc:HGNC:18052]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036126//sperm flagellum	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008584//male gonad development;GO:0016567//protein ubiquitination	--
ENSG00000137076	54.859	57.415	58.858	59.304	61.439	50.016	9812	10322	7775	7857	9284	6509	TLN1	talin 1 [Source:HGNC Symbol;Acc:HGNC:11845]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cellular community - eukaryotes;Immune system	ko05131//Shigellosis;ko05166//Human T-cell leukemia virus 1 infection;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04611//Platelet activation	K06271;K06271;K06271;K06271;K06271	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0017166//vinculin binding;GO:0030274//LIM domain binding;GO:0035091//phosphatidylinositol binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007043//cell-cell junction assembly;GO:0007044//cell-substrate junction assembly;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0033622//integrin activation;GO:0051893//regulation of focal adhesion assembly;GO:0070527//platelet aggregation;GO:0098609//cell-cell adhesion	--
ENSG00000137077	0	0	0	0	0	0	0	0	0	0	0	0	CCL21	C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K16062;K16062;K16062;K16062	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031732//CCR7 chemokine receptor binding;GO:0042379//chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0001768//establishment of T cell polarity;GO:0001771//immunological synapse formation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002407//dendritic cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0010820//positive regulation of T cell chemotaxis;GO:0016477//cell migration;GO:0030593//neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0031295//T cell costimulation;GO:0031529//ruffle organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0034695//response to prostaglandin E;GO:0035759//mesangial cell-matrix adhesion;GO:0038116//chemokine (C-C motif) ligand 21 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043547//positive regulation of GTPase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048469//cell maturation;GO:0050921//positive regulation of chemotaxis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051491//positive regulation of filopodium assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090630//activation of GTPase activity;GO:0097026//dendritic cell dendrite assembly;GO:1903237//negative regulation of leukocyte tethering or rolling;GO:1990869//cellular response to chemokine;GO:2000147//positive regulation of cell motility;GO:2000406//positive regulation of T cell migration;GO:2000529//positive regulation of myeloid dendritic cell chemotaxis;GO:2000548//negative regulation of dendritic cell dendrite assembly;GO:2000669//negative regulation of dendritic cell apoptotic process	--
ENSG00000137078	0	0	0	0	0.047	0	0	0	0	0	1	0	SIT1	signaling threshold regulating transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:17710]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042169//SH2 domain binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0043029//T cell homeostasis;GO:0050863//regulation of T cell activation	--
ENSG00000137080	0	0	0	0	0	0	0	0	0	0	0	0	IFNA21	interferon alpha 21 [Source:HGNC Symbol;Acc:HGNC:5424]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000137090	0	0	0	0	0	0	0	0	0	0	0	0	DMRT1	doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0002176//male germ cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0007548//sex differentiation;GO:0008354//germ cell migration;GO:0008584//male gonad development;GO:0030154//cell differentiation;GO:0030238//male sex determination;GO:0035556//intracellular signal transduction;GO:0045835//negative regulation of meiotic nuclear division;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046661//male sex differentiation;GO:0048599//oocyte development;GO:0060008//Sertoli cell differentiation;GO:0060009//Sertoli cell development;GO:0060903//positive regulation of meiosis I;GO:1900107//regulation of nodal signaling pathway;GO:2000020//positive regulation of male gonad development"	DM
ENSG00000137094	6.907	5.442	7.943	5.017	3.241	6.115	219	240	169	115	100	144	DNAJB5	DnaJ heat shock protein family (Hsp40) member B5 [Source:HGNC Symbol;Acc:HGNC:14887]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000137098	0.698	1.274	1.032	0.674	0.729	1.067	22.03	37.05	24	16	19	23.02	SPAG8	sperm associated antigen 8 [Source:HGNC Symbol;Acc:HGNC:14105]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:0032092//positive regulation of protein binding;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000137100	45.113	41.669	47.598	49.644	44.6	42.359	774	718	604	630	647	528	DCTN3	dynactin subunit 3 [Source:HGNC Symbol;Acc:HGNC:2713]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection	K10425;K10425;K10425;K10425	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0005875//microtubule associated complex;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0048471//perinuclear region of cytoplasm"	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0007049//cell cycle;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000137101	0.094	0.316	0.256	0.383	0.261	0.173	3	8	6	9	6	4	CD72	CD72 molecule [Source:HGNC Symbol;Acc:HGNC:1696]	Organismal Systems	Immune system	ko04662//B cell receptor signaling pathway	K06504	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007155//cell adhesion	--
ENSG00000137103	12.025	11.433	11.983	14.086	13.693	12.005	1030	1037.04	851	870.01	1059	816	TMEM8B	transmembrane protein 8B [Source:HGNC Symbol;Acc:HGNC:21427]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007346//regulation of mitotic cell cycle;GO:0040008//regulation of growth	--
ENSG00000137106	74.062	73.73	78.359	80.757	75.907	74.231	1926	1924	1508	1559	1668	1409	GRHPR	glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00620//Pyruvate metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K00049;K00049;K00049;K00049	GO:0005737//cytoplasm;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1902494//catalytic complex	"GO:0005515//protein binding;GO:0008465//glycerate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016618//hydroxypyruvate reductase activity;GO:0030267//glyoxylate reductase (NADP+) activity;GO:0031406//carboxylic acid binding;GO:0042803//protein homodimerization activity;GO:0050661//NADP binding;GO:0051287//NAD binding;GO:0070402//NADPH binding"	GO:0019752//carboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0046487//glyoxylate metabolic process	--
ENSG00000137124	19.595	16.981	17.117	14.81	17.941	17.791	1157	1072	794	689	952	813	ALDH1B1	aldehyde dehydrogenase 1 family member B1 [Source:HGNC Symbol;Acc:HGNC:407]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism;ko00770//Pantothenate and CoA biosynthesis"	K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity;GO:0051287//NAD binding"	GO:0005975//carbohydrate metabolic process;GO:0006068//ethanol catabolic process	--
ENSG00000137133	6.166	5.318	5.431	7.019	7.386	9.495	83	71.96	54	69.99	84	93	HINT2	histidine triad nucleotide binding protein 2 [Source:HGNC Symbol;Acc:HGNC:18344]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0043530//adenosine 5'-monophosphoramidase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006915//apoptotic process;GO:0016042//lipid catabolic process;GO:2000757//negative regulation of peptidyl-lysine acetylation	--
ENSG00000137135	0.681	0.578	1.044	0.983	1.223	1.105	59.9	51.67	66.36	64.34	93.64	67.8	ARHGEF39	Rho guanine nucleotide exchange factor 39 [Source:HGNC Symbol;Acc:HGNC:25909]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0030335//positive regulation of cell migration;GO:0050790//regulation of catalytic activity	--
ENSG00000137142	4.38	4.815	5.272	4.727	3.825	3.976	324	358	288	259	239	214	IGFBPL1	insulin like growth factor binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:20081]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding	GO:0001558//regulation of cell growth;GO:0009966//regulation of signal transduction;GO:0071228//cellular response to tumor cell	--
ENSG00000137145	7.818	6.047	5.64	4.368	4.503	6.085	1173	961	631	533	613	685	DENND4C	DENN domain containing 4C [Source:HGNC Symbol;Acc:HGNC:26079]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030904//retromer complex;GO:0031410//cytoplasmic vesicle;GO:0032593//insulin-responsive compartment;GO:0043231//intracellular membrane-bounded organelle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0015031//protein transport;GO:0032483//regulation of Rab protein signal transduction;GO:0032869//cellular response to insulin stimulus;GO:0050790//regulation of catalytic activity;GO:0072659//protein localization to plasma membrane	--
ENSG00000137154	585.221	628.104	552.653	517.327	485.617	467.666	12870	13841	8965	8504	8975	7461	RPS6	ribosomal protein S6 [Source:HGNC Symbol;Acc:HGNC:10429]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Genetic Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Environmental adaptation;Cancer: overview;Signal transduction;Endocrine system;Translation;Signal transduction;Signal transduction;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04714//Thermogenesis;ko05205//Proteoglycans in cancer;ko04150//mTOR signaling pathway;ko04910//Insulin signaling pathway;ko03010//Ribosome;ko04371//Apelin signaling pathway;ko04066//HIF-1 signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K02991;K02991;K02991;K02991;K02991;K02991;K02991;K02991;K02991;K02991	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0030425//dendrite;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0001890//placenta development;GO:0002181//cytoplasmic translation;GO:0002309//T cell proliferation involved in immune response;GO:0006364//rRNA processing;GO:0006412//translation;GO:0006924//activation-induced cell death of T cells;GO:0007369//gastrulation;GO:0008284//positive regulation of cell population proliferation;GO:0022605//mammalian oogenesis stage;GO:0031929//TOR signaling;GO:0033077//T cell differentiation in thymus;GO:0042274//ribosomal small subunit biogenesis;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0048821//erythrocyte development	--
ENSG00000137161	42.113	45.987	43.701	41.253	44.424	37.876	1250	1372	958	907	1114	818	CNPY3	canopy FGF signaling regulator 3 [Source:HGNC Symbol;Acc:HGNC:11968]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0002376//immune system process;GO:0045087//innate immune response	--
ENSG00000137166	27.368	31.762	33.067	39.003	38.149	36.386	2635	2975	2269	2583	2934	2440	FOXP4	forkhead box P4 [Source:HGNC Symbol;Acc:HGNC:20842]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0048513//animal organ development"	Fork_head
ENSG00000137168	15.742	17.022	19.204	16.958	16.713	19.799	495	538	446	395	444	453	PPIL1	peptidylprolyl isomerase like 1 [Source:HGNC Symbol;Acc:HGNC:9260]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12733	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0097718//disordered domain specific binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006397//mRNA processing;GO:0006457//protein folding;GO:0008380//RNA splicing;GO:1990403//embryonic brain development"	--
ENSG00000137171	11.254	10.33	12.684	13.913	13.402	14.509	533	498	455	469	552	480	KLC4	kinesin light chain 4 [Source:HGNC Symbol;Acc:HGNC:21624]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection	K10407;K10407;K10407;K10407;K10407;K10407;K10407	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0005515//protein binding	-	--
ENSG00000137177	36.083	34.325	34.528	28.594	28.083	30.777	4503	4226	3073	2560	2835	2727	KIF13A	kinesin family member 13A [Source:HGNC Symbol;Acc:HGNC:14566]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0032588//trans-Golgi network membrane	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0006886//intracellular protein transport;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0032438//melanosome organization;GO:0032465//regulation of cytokinesis;GO:0035459//vesicle cargo loading;GO:0043001//Golgi to plasma membrane protein transport;GO:0051301//cell division;GO:0072383//plus-end-directed vesicle transport along microtubule	--
ENSG00000137185	6.293	7.057	5.901	6.243	6.066	5.154	211	228	137	156	181	133	ZSCAN9	zinc finger and SCAN domain containing 9 [Source:HGNC Symbol;Acc:HGNC:12984]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000137193	13.003	11.854	9.515	7.489	7.959	9.511	729	668	394	311	377	388	PIM1	"Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Signal transduction;Endocrine and metabolic disease;Cancer: specific types	ko05200//Pathways in cancer;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05221//Acute myeloid leukemia	K04702;K04702;K04702;K04702;K04702	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008134//transcription factor binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030145//manganese ion binding;GO:0043024//ribosomal small subunit binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007275//multicellular organism development;GO:0016310//phosphorylation;GO:0022898//regulation of transmembrane transporter activity;GO:0043066//negative regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0070561//vitamin D receptor signaling pathway;GO:0090336//positive regulation of brown fat cell differentiation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:1905062//positive regulation of cardioblast proliferation;GO:1990748//cellular detoxification"	--
ENSG00000137198	36.766	37.818	40.647	45.448	42.799	44.291	1150	1189	939	1053	1131	1008	GMPR	guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00364;K00364	GO:0005829//cytosol;GO:1902560//GMP reductase complex	GO:0003824//catalytic activity;GO:0003920//GMP reductase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006144//purine nucleobase metabolic process;GO:0006163//purine nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009409//response to cold	--
ENSG00000137200	13.241	16.128	17.636	15.446	16.327	14.458	1056	1218	1016	903	1082	806	CMTR1	cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0016740//transferase activity	GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0032259//methylation;GO:0043414//macromolecule methylation;GO:0080009//mRNA methylation;GO:0097309//cap1 mRNA methylation	--
ENSG00000137203	0.106	0.152	0.173	0.298	0.274	0.098	3	6	6	3	12	1	TFAP2A	transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0140536//nuclear receptor corepressor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0003404//optic vesicle morphogenesis;GO:0003409//optic cup structural organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010842//retina layer formation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0021559//trigeminal nerve development;GO:0021623//oculomotor nerve formation;GO:0030501//positive regulation of bone mineralization;GO:0035115//embryonic forelimb morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042472//inner ear morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045595//regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048856//anatomical structure development;GO:0060021//roof of mouth development;GO:0060349//bone morphogenesis;GO:0061029//eyelid development in camera-type eye;GO:0070172//positive regulation of tooth mineralization;GO:0071281//cellular response to iron ion;GO:2000378//negative regulation of reactive oxygen species metabolic process"	AP-2
ENSG00000137204	0	0	0	0	0	0	0	0	0	0	0	0	SLC22A7	solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]	Organismal Systems	Digestive system	ko04976//Bile secretion	K08204	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport	--
ENSG00000137207	112.534	109.19	116.077	121.905	113.609	110.494	3399	3303	2599	2751	2897	2441	YIPF3	Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0030154//cell differentiation	--
ENSG00000137210	39.143	38.567	43.893	42.448	36.342	39.636	736	732	613	582	577	533	TMEM14B	transmembrane protein 14B [Source:HGNC Symbol;Acc:HGNC:21384]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:0021987//cerebral cortex development;GO:0061351//neural precursor cell proliferation;GO:0070453//regulation of heme biosynthetic process;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000137216	24.98	26.497	26.78	31.52	30.874	31.559	1663	1749	1322	1508	1688	1539	TMEM63B	transmembrane protein 63B [Source:HGNC Symbol;Acc:HGNC:17735]	-	-	-	-	GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005227//calcium activated cation channel activity;GO:0008381//mechanosensitive ion channel activity;GO:1990760//osmolarity-sensing cation channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000137218	1.526	1.566	2.937	1.533	2.126	1.994	68	71	55	51	81	63	FRS3	fibroblast growth factor receptor substrate 3 [Source:HGNC Symbol;Acc:HGNC:16970]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway	--
ENSG00000137221	9.096	8.949	13.053	12.926	12.237	14.593	458	514.02	467	474	520	521	TJAP1	tight junction associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17949]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06105	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000137225	0	0	0	0	0	0	0	0	0	0	0	0	CAPN11	calpain 11 [Source:HGNC Symbol;Acc:HGNC:1478]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000137251	0	0	0.037	0	0.097	0	0	0	1	0	3	0	TINAG	tubulointerstitial nephritis antigen [Source:HGNC Symbol;Acc:HGNC:14599]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005764//lysosome	GO:0000166//nucleotide binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion	--
ENSG00000137252	0.504	0.372	0.762	0.497	0.37	0.906	18	15	20	12	11	24	HCRTR2	hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4849]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04239	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0016499//orexin receptor activity;GO:0017046//peptide hormone binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007631//feeding behavior;GO:0010840//regulation of circadian sleep/wake cycle, wakefulness;GO:0022410//circadian sleep/wake cycle process;GO:0040011//locomotion;GO:0051480//regulation of cytosolic calcium ion concentration"	--
ENSG00000137261	0.185	0.188	0.099	0.062	0.036	0.06	24	26	10	6	4	6	KIAA0319	KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007399//nervous system development;GO:0010996//response to auditory stimulus;GO:0030517//negative regulation of axon extension;GO:0033555//multicellular organismal response to stress;GO:0048692//negative regulation of axon extension involved in regeneration;GO:0060391//positive regulation of SMAD protein signal transduction;GO:2000171//negative regulation of dendrite development	--
ENSG00000137265	0	0.009	0	0	0.075	0	0	1	0	0	2	0	IRF4	interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119]	Organismal Systems	Immune system	ko04659//Th17 cell differentiation	K09445	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032733//positive regulation of interleukin-10 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0042110//T cell activation;GO:0042832//defense response to protozoan;GO:0043011//myeloid dendritic cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045622//regulation of T-helper cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0072540//T-helper 17 cell lineage commitment;GO:0120162//positive regulation of cold-induced thermogenesis"	IRF
ENSG00000137266	6.221	6.5	7.187	6.227	5.846	6.624	669	728	609	512	566.22	536	SLC22A23	solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0055085//transmembrane transport	--
ENSG00000137267	11.936	12.687	8.656	14.962	13.246	8.721	400.1	427.44	214.29	371.48	375.1	212.69	TUBB2A	tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0001764//neuron migration;GO:0007017//microtubule-based process	--
ENSG00000137269	18.075	17.342	16.773	14.944	14.536	17.747	1173	1139	811	725	804	835	LRRC1	leucine rich repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:14307]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000137270	0	0	0	0	0	0	0	0	0	0	0	0	GCM1	glial cells missing transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:4197]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K21598	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0042063//gliogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060018//astrocyte fate commitment;GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060800//regulation of cell differentiation involved in embryonic placenta development"	GCM
ENSG00000137273	0	0.02	0	0	0	0	0	1	0	0	0	0	FOXF2	forkhead box F2 [Source:HGNC Symbol;Acc:HGNC:3810]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001093//TFIIB-class transcription factor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0140296//general transcription initiation factor binding"	"GO:0001837//epithelial to mesenchymal transition;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009887//animal organ morphogenesis;GO:0030198//extracellular matrix organization;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048566//embryonic digestive tract development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048806//genitalia development;GO:0060021//roof of mouth development;GO:1902914//regulation of protein polyubiquitination"	Fork_head
ENSG00000137274	8.134	7.786	9.191	8.766	8.243	7.256	306	280	250	222	250	207	BPHL	biphenyl hydrolase like [Source:HGNC Symbol;Acc:HGNC:1094]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0047658//alpha-amino-acid esterase activity	GO:0006520//cellular amino acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance	--
ENSG00000137275	7.838	7.437	6.861	5.796	5.711	6.087	659	636	431	365	408	366	RIPK1	receptor interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:10019]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Immune system;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Immune system;Immune system;Immune system	ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko05160//Hepatitis C;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861;K02861	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031264//death-inducing signaling complex;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0097342//ripoptosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0070513//death domain binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0008219//cell death;GO:0010940//positive regulation of necrotic cell death;GO:0010942//positive regulation of cell death;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034612//response to tumor necrosis factor;GO:0036289//peptidyl-serine autophosphorylation;GO:0042327//positive regulation of phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0044093//positive regulation of molecular function;GO:0044257//cellular protein catabolic process;GO:0045651//positive regulation of macrophage differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0050729//positive regulation of inflammatory response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060545//positive regulation of necroptotic process;GO:0060546//negative regulation of necroptotic process;GO:0070105//positive regulation of interleukin-6-mediated signaling pathway;GO:0070231//T cell apoptotic process;GO:0070266//necroptotic process;GO:0070301//cellular response to hydrogen peroxide;GO:0070926//regulation of ATP:ADP antiporter activity;GO:0071310//cellular response to organic substance;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097300//programmed necrotic cell death;GO:0097343//ripoptosome assembly;GO:0097527//necroptotic signaling pathway;GO:1901026//ripoptosome assembly involved in necroptotic process;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:1905206//positive regulation of hydrogen peroxide-induced cell death;GO:1990000//amyloid fibril formation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000137285	12.708	12.308	10.358	18.138	15.323	15.803	506.6	493.21	304.99	535.63	516.1	458.4	TUBB2B	tubulin beta 2B class IIb [Source:HGNC Symbol;Acc:HGNC:30829]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle;GO:0098685//Schaffer collateral - CA1 synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046982//protein heterodimerization activity	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0001764//neuron migration;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0007399//nervous system development;GO:0050804//modulation of chemical synaptic transmission;GO:1902669//positive regulation of axon guidance;GO:1990403//embryonic brain development	--
ENSG00000137288	13.879	14.357	13.355	15.371	11.375	13.21	243	253	179	179	174	172	UQCC2	ubiquinol-cytochrome c reductase complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:21237]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016604//nuclear body;GO:0042645//mitochondrial nucleoid	GO:0005515//protein binding	GO:0002082//regulation of oxidative phosphorylation;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0050796//regulation of insulin secretion;GO:0070131//positive regulation of mitochondrial translation;GO:2001014//regulation of skeletal muscle cell differentiation	--
ENSG00000137309	31.912	29.151	36.779	53.944	43.835	46.485	1269	1153	1072	1569	1476	1318	HMGA1	high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0035985//senescence-associated heterochromatin focus;GO:0090575//RNA polymerase II transcription regulator complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030374//nuclear receptor coactivator activity;GO:0030527//structural constituent of chromatin;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0046965//retinoid X receptor binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity	"GO:0006268//DNA unwinding involved in DNA replication;GO:0006284//base-excision repair;GO:0006337//nucleosome disassembly;GO:0006355//regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090402//oncogene-induced cell senescence"	HMGA
ENSG00000137310	2.675	2.709	2.217	2.104	1.638	1.389	173	160	103	92	81	68	TCF19	transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0010468//regulation of gene expression	Others
ENSG00000137312	76.506	75.401	77.924	72.465	70.304	73.274	2710	2728	2081	1917	2211	2003	FLOT1	flotillin 1 [Source:HGNC Symbol;Acc:HGNC:3757]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K07192	GO:0001931//uropod;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0008180//COP9 signalosome;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016600//flotillin complex;GO:0030027//lamellipodium;GO:0030864//cortical actin cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0034451//centriolar satellite;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0044291//cell-cell contact zone;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0070062//extracellular exosome;GO:0098691//dopaminergic synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0002020//protease binding;GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding	"GO:0001819//positive regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0002090//regulation of receptor internalization;GO:0007409//axonogenesis;GO:0022617//extracellular matrix disassembly;GO:0032092//positive regulation of protein binding;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0032728//positive regulation of interferon-beta production;GO:0033227//dsRNA transport;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0035023//regulation of Rho protein signal transduction;GO:0044854//plasma membrane raft assembly;GO:0044857//plasma membrane raft organization;GO:0045807//positive regulation of endocytosis;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0050821//protein stabilization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051580//regulation of neurotransmitter uptake;GO:0070528//protein kinase C signaling;GO:0071360//cellular response to exogenous dsRNA;GO:0072659//protein localization to plasma membrane;GO:1901741//positive regulation of myoblast fusion;GO:1901890//positive regulation of cell junction assembly;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin"	--
ENSG00000137331	26.708	33.717	27.622	17.669	24.573	18.702	688	873	526	337	535	351	IER3	immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:2001020//regulation of response to DNA damage stimulus	--
ENSG00000137337	5.293	7.031	7.165	6.401	7.836	5.922	635	765	597	590	671	490	MDC1	mediator of DNA damage checkpoint 1 [Source:HGNC Symbol;Acc:HGNC:21163]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005925//focal adhesion;GO:0016604//nuclear body;GO:0043229//intracellular organelle	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0070975//FHA domain binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031573//mitotic intra-S DNA damage checkpoint signaling	--
ENSG00000137338	1.619	1.147	1.309	1.033	0.85	0.919	104	74	62	49	46	43	PGBD1	piggyBac transposable element derived 1 [Source:HGNC Symbol;Acc:HGNC:19398]	-	-	-	-	GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006897//endocytosis	--
ENSG00000137343	7.185	6.935	6.834	6.676	6.539	7.008	275	287	228	202	238	206	ATAT1	alpha tubulin acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21186]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0072686//mitotic spindle;GO:0097427//microtubule bundle	"GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019799//tubulin N-acetyltransferase activity"	GO:0006473//protein acetylation;GO:0007283//spermatogenesis;GO:0021542//dentate gyrus development;GO:0045598//regulation of fat cell differentiation;GO:0048666//neuron development;GO:0060271//cilium assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071929//alpha-tubulin acetylation;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly	--
ENSG00000137364	8.116	7.879	9.287	6.889	6.595	8.636	536	523	453	337	368	415	TPMT	thiopurine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:12014]	Metabolism	Xenobiotics biodegradation and metabolism	ko00983//Drug metabolism - other enzymes	K00569	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008119//thiopurine S-methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0006139//nucleobase-containing compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0032259//methylation	--
ENSG00000137392	0	0	0	0	0	0	0	0	0	0	0	0	CLPS	colipase [Source:HGNC Symbol;Acc:HGNC:2085]	Organismal Systems	Digestive system	ko04975//Fat digestion and absorption	K14460	GO:0005576//extracellular region	GO:0008047//enzyme activator activity	GO:0006629//lipid metabolic process;GO:0007586//digestion;GO:0009617//response to bacterium;GO:0016042//lipid catabolic process;GO:0032094//response to food;GO:0050790//regulation of catalytic activity	--
ENSG00000137393	1.236	1.02	1.193	1.112	1.338	1.001	129	107	92	86	118	76	RNF144B	ring finger protein 144B [Source:HGNC Symbol;Acc:HGNC:21578]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process	--
ENSG00000137404	7.538	8.632	9.82	11.813	12.489	10.684	219	251	211	253	309	222	NRM	nurim [Source:HGNC Symbol;Acc:HGNC:8003]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000137409	102.35	104.311	107.24	116.397	113.004	113.576	4231	4343	3261	3557	3942	3419	MTCH1	mitochondrial carrier 1 [Source:HGNC Symbol;Acc:HGNC:17586]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009966//regulation of signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0045161//neuronal ion channel clustering	--
ENSG00000137411	2.572	3.097	4.109	4.266	3.495	4.185	131	180	158	141	147	163	VARS2	"valyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21642]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01873	GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004832//valine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006438//valyl-tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000137413	3.813	3.792	4.912	2.884	4.066	4.756	228	273	210	185	221	234	TAF8	TATA-box binding protein associated factor 8 [Source:HGNC Symbol;Acc:HGNC:17300]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K14649	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046982//protein heterodimerization activity	GO:0001112//DNA-templated transcription open complex formation;GO:0001833//inner cell mass cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0030154//cell differentiation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045598//regulation of fat cell differentiation;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0051457//maintenance of protein location in nucleus;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000137414	14.153	12.501	13.09	12.018	11.572	12.331	1333	1201	926	845	934	864	FAM8A1	family with sequence similarity 8 member A1 [Source:HGNC Symbol;Acc:HGNC:16372]	-	-	-	-	GO:0000836//Hrd1p ubiquitin ligase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000137434	0.282	0.468	0.335	0.557	0	0.527	3	5	3	4	0	4	C6orf52	chromosome 6 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:20881]	-	-	-	-	-	-	-	--
ENSG00000137440	0	0.036	0	0	0	0	0	1	0	0	0	0	FGFBP1	fibroblast growth factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19695]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding;GO:0019838//growth factor binding	GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	--
ENSG00000137441	0.044	0	0	0	0	0	1	0	0	0	0	0	FGFBP2	fibroblast growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29451]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0019838//growth factor binding	GO:0007267//cell-cell signaling	--
ENSG00000137449	10.404	8.551	9.116	6.343	7.024	8.953	1277	1134	872	627	776	800	CPEB2	cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K02602;K02602	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0045202//synapse;GO:1990124//messenger ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005095//GTPase inhibitor activity;GO:0008135//translation factor activity, RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0043022//ribosome binding;GO:0043023//ribosomal large subunit binding;GO:0043024//ribosomal small subunit binding;GO:0045182//translation regulator activity"	GO:0006412//translation;GO:0006417//regulation of translation;GO:0032869//cellular response to insulin stimulus;GO:0034260//negative regulation of GTPase activity;GO:0034599//cellular response to oxidative stress;GO:0071243//cellular response to arsenic-containing substance;GO:0071456//cellular response to hypoxia;GO:1900248//negative regulation of cytoplasmic translational elongation;GO:2000766//negative regulation of cytoplasmic translation	--
ENSG00000137460	0.095	0.102	0.139	0.049	0.087	0.09	13	14	14	5	10	9	FHDC1	FH2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29363]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0008017//microtubule binding	GO:0030030//cell projection organization;GO:0043149//stress fiber assembly;GO:0060271//cilium assembly;GO:0090161//Golgi ribbon formation	--
ENSG00000137462	0.415	0.37	0.351	0.48	0.192	0.271	18	20	16	21	10	14	TLR2	toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: parasitic;Infectious disease: viral;Immune disease;Infectious disease: viral;Infectious disease: parasitic;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05146//Amoebiasis;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko05162//Measles;ko05140//Leishmaniasis;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko05144//Malaria	K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159;K10159	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031226//intrinsic component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0035354//Toll-like receptor 1-Toll-like receptor 2 protein complex;GO:0035355//Toll-like receptor 2-Toll-like receptor 6 protein complex;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0044297//cell body;GO:0045121//membrane raft	"GO:0001530//lipopolysaccharide binding;GO:0001540//amyloid-beta binding;GO:0001875//lipopolysaccharide immune receptor activity;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035325//Toll-like receptor binding;GO:0038023//signaling receptor activity;GO:0038187//pattern recognition receptor activity;GO:0042497//triacyl lipopeptide binding;GO:0042802//identical protein binding;GO:0042834//peptidoglycan binding;GO:0044877//protein-containing complex binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating;GO:0071723//lipopeptide binding"	GO:0001666//response to hypoxia;GO:0001774//microglial cell activation;GO:0001775//cell activation;GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006691//leukotriene metabolic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007252//I-kappaB phosphorylation;GO:0007612//learning;GO:0008285//negative regulation of cell population proliferation;GO:0009636//response to toxic substance;GO:0010628//positive regulation of gene expression;GO:0014005//microglia development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032289//central nervous system myelin formation;GO:0032493//response to bacterial lipoprotein;GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone;GO:0032722//positive regulation of chemokine production;GO:0032728//positive regulation of interferon-beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032741//positive regulation of interleukin-18 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032868//response to insulin;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0042495//detection of triacyl bacterial lipopeptide;GO:0042496//detection of diacyl bacterial lipopeptide;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046209//nitric oxide metabolic process;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050729//positive regulation of inflammatory response;GO:0050765//negative regulation of phagocytosis;GO:0050830//defense response to Gram-positive bacterium;GO:0050896//response to stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051964//negative regulation of synapse assembly;GO:0070542//response to fatty acid;GO:0071221//cellular response to bacterial lipopeptide;GO:0071223//cellular response to lipoteichoic acid;GO:0071346//cellular response to interferon-gamma;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903974//positive regulation of cellular response to macrophage colony-stimulating factor stimulus;GO:1904466//positive regulation of matrix metallopeptidase secretion	--
ENSG00000137463	5.396	5.604	3.677	6.217	4.289	4.593	137	143	68.94	116.91	92	84.85	MGARP	mitochondria localized glutamic acid rich protein [Source:HGNC Symbol;Acc:HGNC:29969]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0006626//protein targeting to mitochondrion;GO:0008089//anterograde axonal transport;GO:0008090//retrograde axonal transport;GO:0010822//positive regulation of mitochondrion organization;GO:0019896//axonal transport of mitochondrion;GO:0071383//cellular response to steroid hormone stimulus;GO:0071456//cellular response to hypoxia;GO:0097211//cellular response to gonadotropin-releasing hormone	--
ENSG00000137473	0.266	0.198	0.12	0.22	0.096	0.112	12	9	4	6	3	3	TTC29	tetratricopeptide repeat domain 29 [Source:HGNC Symbol;Acc:HGNC:29936]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0044782//cilium organization	--
ENSG00000137474	38.123	42.294	44.414	35.731	38.268	34.362	5413	5965	4708	3787	4559	3382	MYO7A	myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016324//apical plasma membrane;GO:0016459//myosin complex;GO:0030054//cell junction;GO:0031982//vesicle;GO:0032391//photoreceptor connecting cilium;GO:0032420//stereocilium;GO:0042470//melanosome;GO:0045202//synapse;GO:0120025//plasma membrane bounded cell projection;GO:0120044//stereocilium base	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0030507//spectrin binding;GO:0051015//actin filament binding	GO:0001845//phagolysosome assembly;GO:0006886//intracellular protein transport;GO:0006909//phagocytosis;GO:0007015//actin filament organization;GO:0007040//lysosome organization;GO:0007423//sensory organ development;GO:0007600//sensory perception;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0030030//cell projection organization;GO:0030048//actin filament-based movement;GO:0030050//vesicle transport along actin filament;GO:0034613//cellular protein localization;GO:0042462//eye photoreceptor cell development;GO:0042472//inner ear morphogenesis;GO:0042490//mechanoreceptor differentiation;GO:0042491//inner ear auditory receptor cell differentiation;GO:0048563//post-embryonic animal organ morphogenesis;GO:0048839//inner ear development;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0051875//pigment granule localization;GO:0051904//pigment granule transport;GO:0060088//auditory receptor cell stereocilium organization;GO:0060113//inner ear receptor cell differentiation;GO:0060122//inner ear receptor cell stereocilium organization	--
ENSG00000137478	11.01	10.451	8.328	5.776	7.119	9.812	962.29	939.87	569	382.99	539	465	FCHSD2	FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0055037//recycling endosome;GO:0120043//stereocilium shaft	"GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	GO:0006897//endocytosis;GO:0007274//neuromuscular synaptic transmission;GO:0015031//protein transport;GO:0030833//regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0061024//membrane organization;GO:0072583//clathrin-dependent endocytosis;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000137486	18.996	15.159	25.183	21.165	19.717	31.049	1305	1135	1262	1199	1214	1526	ARRB1	arrestin beta 1 [Source:HGNC Symbol;Acc:HGNC:711]	Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Sensory system;Signal transduction;Transport and catabolism;Cancer: overview;Immune system;Nervous system;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Signal transduction	"ko04740//Olfactory transduction;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction;ko04929//GnRH secretion;ko04340//Hedgehog signaling pathway"	K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030659//cytoplasmic vesicle membrane;GO:0031143//pseudopodium;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0001664//G protein-coupled receptor binding;GO:0003713//transcription coactivator activity;GO:0004857//enzyme inhibitor activity;GO:0005096//GTPase activator activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0031701//angiotensin receptor binding;GO:1990763//arrestin family protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002031//G protein-coupled receptor internalization;GO:0002092//positive regulation of receptor internalization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0009968//negative regulation of signal transduction;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0032717//negative regulation of interleukin-8 production;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035066//positive regulation of histone acetylation;GO:0043086//negative regulation of catalytic activity;GO:0043149//stress fiber assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045746//negative regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090240//positive regulation of histone H4 acetylation	--
ENSG00000137491	0	0.015	0	0	0.035	0	0	1	0	0	2	0	SLCO2B1	solute carrier organic anion transporter family member 2B1 [Source:HGNC Symbol;Acc:HGNC:10962]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0042167//heme catabolic process;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000137492	22.045	21.24	17.851	19.138	19.945	17.198	1335	1285	817	872	1063	755	THAP12	THAP domain containing 12 [Source:HGNC Symbol;Acc:HGNC:9440]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity	GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation	THAP
ENSG00000137494	5.261	4.792	4.423	4.562	4.164	5.544	379	340	241	226	262	298	ANKRD42	ankyrin repeat domain 42 [Source:HGNC Symbol;Acc:HGNC:26752]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0051059//NF-kappaB binding	GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1900017//positive regulation of cytokine production involved in inflammatory response	--
ENSG00000137496	0.751	0.601	0.587	0.884	0.876	0.804	38.01	25.44	18.41	31.73	39.56	26.76	IL18BP	interleukin 18 binding protein [Source:HGNC Symbol;Acc:HGNC:5987]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0042007//interleukin-18 binding;GO:0048019//receptor antagonist activity	GO:0032496//response to lipopolysaccharide;GO:0042088//T-helper 1 type immune response;GO:0070301//cellular response to hydrogen peroxide;GO:0071356//cellular response to tumor necrosis factor;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000137497	83.365	93.316	89.526	88.593	110.432	85.641	9445.99	9930.56	7228.59	7073.27	8715.44	7207.24	NUMA1	nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:HGNC:8059]	-	-	-	-	GO:0000139//Golgi membrane;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0016363//nuclear matrix;GO:0019897//extrinsic component of plasma membrane;GO:0030425//dendrite;GO:0031616//spindle pole centrosome;GO:0032991//protein-containing complex;GO:0035371//microtubule plus-end;GO:0036449//microtubule minus-end;GO:0043025//neuronal cell body;GO:0055028//cortical microtubule;GO:0061673//mitotic spindle astral microtubule;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0097427//microtubule bundle;GO:0097431//mitotic spindle pole;GO:0097575//lateral cell cortex;GO:0099738//cell cortex region;GO:1905720//cytoplasmic microtubule bundle;GO:1990023//mitotic spindle midzone	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0044877//protein-containing complex binding;GO:0051010//microtubule plus-end binding;GO:0051011//microtubule minus-end binding;GO:0070840//dynein complex binding;GO:0097718//disordered domain specific binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001578//microtubule bundle formation;GO:0006997//nucleus organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0030513//positive regulation of BMP signaling pathway;GO:0030953//astral microtubule organization;GO:0031116//positive regulation of microtubule polymerization;GO:0032388//positive regulation of intracellular transport;GO:0045618//positive regulation of keratinocyte differentiation;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051798//positive regulation of hair follicle development;GO:0051984//positive regulation of chromosome segregation;GO:0055048//anastral spindle assembly;GO:0060236//regulation of mitotic spindle organization;GO:0090235//regulation of metaphase plate congression;GO:1902365//positive regulation of protein localization to spindle pole body;GO:1902846//positive regulation of mitotic spindle elongation;GO:1904778//positive regulation of protein localization to cell cortex;GO:1905820//positive regulation of chromosome separation;GO:1905832//positive regulation of spindle assembly	--
ENSG00000137500	25.652	20.821	20.826	17.739	19.035	20.433	758	698	443	371	477	445	CCDC90B	coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	-	--
ENSG00000137501	1.268	0.591	0.299	0.47	0.89	0.408	51	46	20	17	41	18	SYTL2	synaptotagmin like 2 [Source:HGNC Symbol;Acc:HGNC:15585]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0042470//melanosome;GO:0070382//exocytic vesicle	"GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019902//phosphatase binding;GO:0031267//small GTPase binding;GO:0042043//neurexin family protein binding"	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport	--
ENSG00000137502	7.702	8.77	6.489	10.252	7.503	6.42	908	752	575	480	621	533	RAB30	"RAB30, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9770]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0031985//Golgi cisterna;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0007030//Golgi organization;GO:0032482//Rab protein signal transduction	--
ENSG00000137504	13.22	11.211	12.434	11.814	11.901	14.86	1398	1194	990	834	1028	1176	CREBZF	CREB/ATF bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:24905]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009615//response to virus;GO:0036500//ATF6-mediated unfolded protein response;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000137507	13.771	14.046	6.566	10.625	13.175	9.152	1167	1185	400	673	918	557	LRRC32	leucine rich repeat containing 32 [Source:HGNC Symbol;Acc:HGNC:4161]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0050431//transforming growth factor beta binding	GO:0001818//negative regulation of cytokine production;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0046007//negative regulation of activated T cell proliferation;GO:0062009//secondary palate development;GO:1901388//regulation of transforming growth factor beta activation;GO:1901398//regulation of transforming growth factor beta3 activation	--
ENSG00000137509	65.997	77.728	70.563	67.926	68.478	71.828	3124	3585	2397	2387	2649	2457	PRCP	prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344]	Organismal Systems;Organismal Systems	Digestive system;Endocrine system	ko04974//Protein digestion and absorption;ko04614//Renin-angiotensin system	K01285;K01285	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045178//basal part of cell;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity	GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0002353//plasma kallikrein-kinin cascade;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0042593//glucose homeostasis;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0060055//angiogenesis involved in wound healing;GO:0097009//energy homeostasis;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000137513	17.318	16.951	19.131	17.689	14.748	18.487	810	797	662	626	597	637	NARS2	"asparaginyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26274]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01893	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004816//asparagine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006421//asparaginyl-tRNA aminoacylation	--
ENSG00000137522	11.357	11.53	11.962	14.376	13.346	13.087	469	541	403	434	489	415	RNF121	ring finger protein 121 [Source:HGNC Symbol;Acc:HGNC:21070]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000137547	25.188	25.311	25.351	30.071	22.257	22.329	517	539	423	461	428	414	MRPL15	mitochondrial ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:14054]	Genetic Information Processing	Translation	ko03010//Ribosome	K02876	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000137558	0.711	0.463	0.468	0.464	0.552	0.551	84	60	44	48	59	56	PI15	peptidase inhibitor 15 [Source:HGNC Symbol;Acc:HGNC:8946]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0030414//peptidase inhibitor activity	GO:0008150//biological_process;GO:0010466//negative regulation of peptidase activity	--
ENSG00000137561	0.128	0.036	0.074	0.099	0.043	0.126	7	2	3	4	2	5	TTPA	alpha tocopherol transfer protein [Source:HGNC Symbol;Acc:HGNC:12404]	-	-	-	-	GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0008431//vitamin E binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0120013//lipid transfer activity;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0001890//placenta development;GO:0001892//embryonic placenta development;GO:0006629//lipid metabolic process;GO:0009636//response to toxic substance;GO:0042360//vitamin E metabolic process;GO:0051180//vitamin transport;GO:0090212//negative regulation of establishment of blood-brain barrier;GO:0120009//intermembrane lipid transfer;GO:1900223//positive regulation of amyloid-beta clearance	--
ENSG00000137563	33.916	32.407	28.701	23.86	20.188	25.089	897	862	560	465	455	486	GGH	gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248]	Human Diseases;Metabolism	Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01523//Antifolate resistance;ko00790//Folate biosynthesis	K01307;K01307	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005773//vacuole;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0042470//melanosome;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1904724//tertiary granule lumen	GO:0005515//protein binding;GO:0008238//exopeptidase activity;GO:0008242//omega peptidase activity;GO:0016787//hydrolase activity;GO:0034722//gamma-glutamyl-peptidase activity	GO:0006508//proteolysis;GO:0046900//tetrahydrofolylpolyglutamate metabolic process	--
ENSG00000137571	0.054	0.08	0.105	0.025	0.155	0.066	10	15	7	1	9	9	SLCO5A1	solute carrier organic anion transporter family member 5A1 [Source:HGNC Symbol;Acc:HGNC:19046]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000137573	286.41	269.28	251.423	170.73	207.78	207.436	24172	22489	15244	10541	14399	12337	SULF1	sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002063//chondrocyte development;GO:0003094//glomerular filtration;GO:0006915//apoptotic process;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0014846//esophagus smooth muscle contraction;GO:0016525//negative regulation of angiogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030201//heparan sulfate proteoglycan metabolic process;GO:0030336//negative regulation of cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0032836//glomerular basement membrane development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048706//embryonic skeletal system development;GO:0051216//cartilage development;GO:0060348//bone development;GO:0060384//innervation;GO:0060686//negative regulation of prostatic bud formation	--
ENSG00000137574	3.824	3.174	3.292	2.416	3.524	3.383	334	267	211	159	241	210	TGS1	trimethylguanosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:17843]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0030532//small nuclear ribonucleoprotein complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity;GO:0071164//RNA trimethylguanosine synthase activity	GO:0000387//spliceosomal snRNP assembly;GO:0001510//RNA methylation;GO:0009452//7-methylguanosine RNA capping;GO:0022613//ribonucleoprotein complex biogenesis;GO:0032259//methylation;GO:0036261//7-methylguanosine cap hypermethylation	--
ENSG00000137575	230.67	227.512	243.173	278.551	254.578	283.335	9944	9856	7772	8932	9253	8929	SDCBP	syndecan binding protein [Source:HGNC Symbol;Acc:HGNC:10662]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005895//interleukin-5 receptor complex;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0035578//azurophil granule lumen;GO:0042470//melanosome;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1903561//extracellular vesicle	"GO:0005109//frizzled binding;GO:0005137//interleukin-5 receptor binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008022//protein C-terminus binding;GO:0008093//cytoskeletal anchor activity;GO:0008289//lipid binding;GO:0019838//growth factor binding;GO:0042043//neurexin family protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045545//syndecan binding;GO:0046875//ephrin receptor binding;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding;GO:0050839//cell adhesion molecule binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002091//negative regulation of receptor internalization;GO:0006612//protein targeting to membrane;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007265//Ras protein signal transduction;GO:0007268//chemical synaptic transmission;GO:0007346//regulation of mitotic cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035556//intracellular signal transduction;GO:0042327//positive regulation of phosphorylation;GO:0046330//positive regulation of JNK cascade;GO:0099054//presynapse assembly;GO:1903543//positive regulation of exosomal secretion;GO:1903553//positive regulation of extracellular exosome assembly"	--
ENSG00000137601	3.095	2.23	2.078	1.555	1.89	1.692	340	245	169	124	169	135	NEK1	NIMA related kinase 1 [Source:HGNC Symbol;Acc:HGNC:7744]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030030//cell projection organization;GO:0051301//cell division;GO:0060271//cilium assembly	--
ENSG00000137628	0.652	0.554	0.651	0.48	0.486	0.432	82	70	60	42	52	39	DDX60	DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0002376//immune system process;GO:0009615//response to virus;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000137634	0	0	0	0	0.026	0	0	0	0	0	1	0	NXPE4	neurexophilin and PC-esterase domain family member 4 [Source:HGNC Symbol;Acc:HGNC:23117]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000137642	5.285	5.978	5.633	4.068	4.46	4.729	1170	1263	852	679	849	718	SORL1	sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005641//nuclear envelope lumen;GO:0005768//endosome;GO:0005769//early endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031985//Golgi cisterna;GO:0032585//multivesicular body membrane;GO:0043025//neuronal cell body;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0097356//perinucleolar compartment	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005041//low-density lipoprotein particle receptor activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0031267//small GTPase binding;GO:0042923//neuropeptide binding	GO:0002024//diet induced thermogenesis;GO:0006605//protein targeting;GO:0006622//protein targeting to lysosome;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007218//neuropeptide signaling pathway;GO:0008283//cell population proliferation;GO:0010897//negative regulation of triglyceride catabolic process;GO:0014910//regulation of smooth muscle cell migration;GO:0016477//cell migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0034067//protein localization to Golgi apparatus;GO:0038020//insulin receptor recycling;GO:0043407//negative regulation of MAP kinase activity;GO:0045053//protein retention in Golgi apparatus;GO:0045732//positive regulation of protein catabolic process;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0050768//negative regulation of neurogenesis;GO:0051604//protein maturation;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:1900168//positive regulation of glial cell-derived neurotrophic factor production;GO:1901215//negative regulation of neuron death;GO:1902430//negative regulation of amyloid-beta formation;GO:1902771//positive regulation of choline O-acetyltransferase activity;GO:1902948//negative regulation of tau-protein kinase activity;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:1902955//positive regulation of early endosome to recycling endosome transport;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902966//positive regulation of protein localization to early endosome;GO:1902997//negative regulation of neurofibrillary tangle assembly;GO:1904179//positive regulation of adipose tissue development;GO:1990845//adaptive thermogenesis;GO:2001137//positive regulation of endocytic recycling	--
ENSG00000137648	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS4	transmembrane serine protease 4 [Source:HGNC Symbol;Acc:HGNC:11878]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K09635	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0009611//response to wounding;GO:0010468//regulation of gene expression;GO:0016485//protein processing;GO:0045967//negative regulation of growth rate;GO:0046598//positive regulation of viral entry into host cell	--
ENSG00000137656	6.312	7.221	6.73	5.493	5.829	7.587	287	330	226	185	222	251	BUD13	BUD13 homolog [Source:HGNC Symbol;Acc:HGNC:28199]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0070274//RES complex;GO:0071005//U2-type precatalytic spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000137672	0	0.082	0	0	0.024	0	0	6	0	0	2	0	TRPC6	transient receptor potential cation channel subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:12338]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signal transduction	ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway	K04969;K04969	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034703//cation channel complex;GO:0036057//slit diaphragm	"GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0042803//protein homodimerization activity;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007338//single fertilization;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051928//positive regulation of calcium ion transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000137673	0	0	0	0	0	0	0	0	0	0	0	0	MMP7	matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174]	Human Diseases;Environmental Information Processing	Infectious disease: viral;Signal transduction	ko05166//Human T-cell leukemia virus 1 infection;ko04310//Wnt signaling pathway	K01397;K01397	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0030574//collagen catabolic process;GO:0031293//membrane protein intracellular domain proteolysis	--
ENSG00000137674	0	0	0	0	0	0	0	0	0	0	0	0	MMP20	matrix metallopeptidase 20 [Source:HGNC Symbol;Acc:HGNC:7167]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030163//protein catabolic process;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0070173//regulation of enamel mineralization;GO:0097186//amelogenesis	--
ENSG00000137675	0	0	0	0	0	0	0	0	0	0	0	0	MMP27	matrix metallopeptidase 27 [Source:HGNC Symbol;Acc:HGNC:14250]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0042406//extrinsic component of endoplasmic reticulum membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process	--
ENSG00000137691	1.435	2.117	0.714	1.241	0.967	0.615	38	41	20	23	21	10	CFAP300	cilia and flagella associated protein 300 [Source:HGNC Symbol;Acc:HGNC:28188]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000137692	10.478	8.537	8.132	9.31	10.513	12.346	335	282	203	198	271	256	DCUN1D5	defective in cullin neddylation 1 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28409]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding	GO:0001558//regulation of cell growth;GO:0006974//cellular response to DNA damage stimulus;GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:2000434//regulation of protein neddylation;GO:2000436//positive regulation of protein neddylation	--
ENSG00000137693	104.814	96.184	96.647	80.316	78.103	93.45	8086	7514	5704	4687	5231	5272	YAP1	Yes1 associated transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:16262]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16687;K16687	GO:0001674//female germ cell nucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0140552//TEAD-YAP complex	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0070064//proline-rich region binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001570//vasculogenesis;GO:0001824//blastocyst development;GO:0001829//trophectodermal cell differentiation;GO:0001894//tissue homeostasis;GO:0003015//heart process;GO:0003143//embryonic heart tube morphogenesis;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010837//regulation of keratinocyte proliferation;GO:0030216//keratinocyte differentiation;GO:0030307//positive regulation of cell growth;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030903//notochord development;GO:0032570//response to progesterone;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0035329//hippo signaling;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046622//positive regulation of organ growth;GO:0048339//paraxial mesoderm development;GO:0048368//lateral mesoderm development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050767//regulation of neurogenesis;GO:0050847//progesterone receptor signaling pathway;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060242//contact inhibition;GO:0060449//bud elongation involved in lung branching;GO:0060487//lung epithelial cell differentiation;GO:0060576//intestinal epithelial cell development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061026//cardiac muscle tissue regeneration;GO:0065003//protein-containing complex assembly;GO:0070102//interleukin-6-mediated signaling pathway;GO:0071300//cellular response to retinoic acid;GO:0071480//cellular response to gamma radiation;GO:0072091//regulation of stem cell proliferation;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1900182//positive regulation of protein localization to nucleus;GO:1902018//negative regulation of cilium assembly;GO:1902459//positive regulation of stem cell population maintenance;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:2000737//negative regulation of stem cell differentiation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000137699	0	0.016	0	0	0.019	0.156	0	1	0	0	1	7	TRIM29	tripartite motif containing 29 [Source:HGNC Symbol;Acc:HGNC:17274]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005912//adherens junction	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0045087//innate immune response;GO:0098609//cell-cell adhesion;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000137700	14.691	16.917	16.179	17.616	18.116	19.082	646	744	529	573	671	614.99	SLC37A4	solute carrier family 37 member 4 [Source:HGNC Symbol;Acc:HGNC:4061]	Organismal Systems	Digestive system	ko04973//Carbohydrate digestion and absorption	K08171	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0015152//glucose-6-phosphate transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0001780//neutrophil homeostasis;GO:0002318//myeloid progenitor cell differentiation;GO:0005977//glycogen metabolic process;GO:0006089//lactate metabolic process;GO:0006641//triglyceride metabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0007584//response to nutrient;GO:0008202//steroid metabolic process;GO:0009749//response to glucose;GO:0014070//response to organic cyclic compound;GO:0015760//glucose-6-phosphate transport;GO:0030593//neutrophil chemotaxis;GO:0032682//negative regulation of chemokine production;GO:0035166//post-embryonic hemopoiesis;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0043085//positive regulation of catalytic activity;GO:0045730//respiratory burst;GO:0055085//transmembrane transport	--
ENSG00000137707	0	0	0.173	0	0	0	0	0	2	0	0	0	BTG4	BTG anti-proliferation factor 4 [Source:HGNC Symbol;Acc:HGNC:13862]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0008285//negative regulation of cell population proliferation;GO:0030182//neuron differentiation;GO:0045930//negative regulation of mitotic cell cycle;GO:0051726//regulation of cell cycle	--
ENSG00000137709	0	0	0	0	0	0	0	0	0	0	0	0	POU2F3	POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864]	Human Diseases;Human Diseases	Infectious disease: viral;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko05417//Lipid and atherosclerosis	K09364;K09364	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008544//epidermis development;GO:0043922//negative regulation by host of viral transcription;GO:0045944//positive regulation of transcription by RNA polymerase II"	Pou
ENSG00000137710	27.502	27.398	22.563	17.932	20.61	22.351	2273	2031	1308	973	1340	1236	RDX	radixin [Source:HGNC Symbol;Acc:HGNC:9944]	Cellular Processes;Human Diseases;Cellular Processes;Human Diseases	Cell motility;Cancer: overview;Cellular community - eukaryotes;Cancer: overview	ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04530//Tight junction;ko05206//MicroRNAs in cancer	K05762;K05762;K05762;K05762	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030315//T-tubule;GO:0030496//midbody;GO:0030864//cortical actin cytoskeleton;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0051286//cell tip;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0051018//protein kinase A binding;GO:0051117//ATPase binding	GO:0008360//regulation of cell shape;GO:0008361//regulation of cell size;GO:0010628//positive regulation of gene expression;GO:0010737//protein kinase A signaling;GO:0030335//positive regulation of cell migration;GO:0032231//regulation of actin filament bundle assembly;GO:0032487//regulation of Rap protein signal transduction;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0034260//negative regulation of GTPase activity;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0043087//regulation of GTPase activity;GO:0045176//apical protein localization;GO:0045184//establishment of protein localization;GO:0045792//negative regulation of cell size;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping;GO:0061028//establishment of endothelial barrier;GO:0072659//protein localization to plasma membrane;GO:0097067//cellular response to thyroid hormone stimulus;GO:1900027//regulation of ruffle assembly;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902115//regulation of organelle assembly;GO:1902966//positive regulation of protein localization to early endosome;GO:1903364//positive regulation of cellular protein catabolic process;GO:1903392//negative regulation of adherens junction organization;GO:2000643//positive regulation of early endosome to late endosome transport	--
ENSG00000137713	7.991	7.248	6.913	7.172	6.284	7.282	542	527	391	387	405	429	PPP2R1B	protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation;Signal transduction;Nervous system	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway;ko04350//TGF-beta signaling pathway;ko04730//Long-term depression	K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456;K03456	GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0006470//protein dephosphorylation;GO:0050790//regulation of catalytic activity;GO:0060561//apoptotic process involved in morphogenesis;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000137714	9.661	9.825	9.468	11.138	10.201	11.402	630	644	456	538	562	541	FDX1	ferredoxin 1 [Source:HGNC Symbol;Acc:HGNC:3638]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0005506//iron ion binding;GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0022900//electron transport chain;GO:0042446//hormone biosynthetic process;GO:0051353//positive regulation of oxidoreductase activity;GO:0071320//cellular response to cAMP;GO:0140647//P450-containing electron transport chain;GO:1904322//cellular response to forskolin	--
ENSG00000137720	10.566	13.125	9.61	11.461	7.29	10.427	172	203	133	134	108	124	C11orf1	chromosome 11 open reading frame 1 [Source:HGNC Symbol;Acc:HGNC:1163]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000137726	7.665	8.558	4.391	1.707	2.549	1.895	258	295	106	44	57	48	FXYD6	FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0008150//biological_process;GO:0043269//regulation of ion transport;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000137727	2.105	1.714	1.466	1.191	1.293	1.028	232	212	133	92	128	80	ARHGAP20	Rho GTPase activating protein 20 [Source:HGNC Symbol;Acc:HGNC:18357]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000137731	0	0	0	0	0	0	0	0	0	0	0	0	FXYD2	FXYD domain containing ion transport regulator 2 [Source:HGNC Symbol;Acc:HGNC:4026]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Digestive system;Digestive system;Circulatory system;Endocrine system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538;K01538	GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0030674//protein-macromolecule adaptor activity;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0030007//cellular potassium ion homeostasis;GO:0036376//sodium ion export across plasma membrane;GO:0043269//regulation of ion transport;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1903408//positive regulation of P-type sodium:potassium-exchanging transporter activity;GO:1990573//potassium ion import across plasma membrane;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000137745	0	0	0	0	0.063	0	0	0	0	0	3	0	MMP13	matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]	Organismal Systems;Organismal Systems;Organismal Systems	Endocrine system;Endocrine system;Immune system	"ko04926//Relaxin signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04657//IL-17 signaling pathway"	K07994;K07994;K07994	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001958//endochondral ossification;GO:0003417//growth plate cartilage development;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030282//bone mineralization;GO:0030574//collagen catabolic process;GO:0044267//cellular protein metabolic process;GO:0051216//cartilage development;GO:0060349//bone morphogenesis;GO:1904645//response to amyloid-beta	--
ENSG00000137747	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS13	transmembrane serine protease 13 [Source:HGNC Symbol;Acc:HGNC:29808]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006897//endocytosis	--
ENSG00000137752	0.136	0.2	0.153	0.102	0.277	0.062	3	4	3	2	4	1	CASP1	caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: bacterial;Immune system;Infectious disease: viral;Cell growth and death;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05014//Amyotrophic lateral sclerosis;ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko04625//C-type lectin receptor signaling pathway;ko05133//Pertussis;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis	K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370;K01370	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0061702//inflammasome complex;GO:0072557//IPAF inflammasome complex;GO:0072558//NLRP1 inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097169//AIM2 inflammasome complex;GO:0097179//protease inhibitor complex	GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0050700//CARD domain binding;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO:0002221//pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007231//osmosensory signaling pathway;GO:0016540//protein autoprocessing;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046456//icosanoid biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0051607//defense response to virus;GO:0070269//pyroptosis;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0071310//cellular response to organic substance;GO:0071346//cellular response to interferon-gamma;GO:0097190//apoptotic signaling pathway;GO:0140447//cytokine precursor processing;GO:0140448//signaling receptor ligand precursor processing;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway	--
ENSG00000137757	0	0	0	0	0	0	0	0	0	0	0	0	CASP5	caspase 5 [Source:HGNC Symbol;Acc:HGNC:1506]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05132//Salmonella infection;ko04621//NOD-like receptor signaling pathway	K04395;K04395	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0072558//NLRP1 inflammasome complex	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0021762//substantia nigra development;GO:0042981//regulation of apoptotic process;GO:0050727//regulation of inflammatory response;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway	--
ENSG00000137760	2.774	1.759	1.942	1.319	2.02	1.851	191	132	121	79	117	107	ALKBH8	"alkB homolog 8, tRNA methyltransferase [Source:HGNC Symbol;Acc:HGNC:25189]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0000049//tRNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016300//tRNA (uracil) methyltransferase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106335//tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	GO:0002098//tRNA wobble uridine modification;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000137764	9.075	10.321	7.993	10.158	12.12	8.946	413	470	276	346	394	307	MAP2K5	mitogen-activated protein kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6845]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Cellular Processes	Signal transduction;Endocrine system;Cardiovascular disease;Nervous system;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04921//Oxytocin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04722//Neurotrophin signaling pathway;ko04540//Gap junction	K04463;K04463;K04463;K04463;K04463	GO:0005634//nucleus;GO:0005819//spindle;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007507//heart development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051247//positive regulation of protein metabolic process;GO:0060761//negative regulation of response to cytokine stimulus;GO:0070375//ERK5 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071499//cellular response to laminar fluid shear stress;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000137766	0.051	0	0	0	0	0	1	0	0	0	0	0	UNC13C	unc-13 homolog C [Source:HGNC Symbol;Acc:HGNC:23149]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15293	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098793//presynapse;GO:0098831//presynaptic active zone cytoplasmic component	GO:0005509//calcium ion binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0017075//syntaxin-1 binding;GO:0019992//diacylglycerol binding;GO:0046872//metal ion binding	"GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0016079//synaptic vesicle exocytosis;GO:0016081//synaptic vesicle docking;GO:0016082//synaptic vesicle priming;GO:0016188//synaptic vesicle maturation;GO:0031914//negative regulation of synaptic plasticity;GO:0035249//synaptic transmission, glutamatergic;GO:0061789//dense core granule priming;GO:0099525//presynaptic dense core vesicle exocytosis"	--
ENSG00000137767	7.927	8.908	6.383	5.051	6.813	4.946	253.19	312	161.69	132	197	120.21	SQOR	sulfide quinone oxidoreductase [Source:HGNC Symbol;Acc:HGNC:20390]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K22470;K22470	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane	GO:0016491//oxidoreductase activity;GO:0048038//quinone binding;GO:0070224//sulfide:quinone oxidoreductase activity;GO:0071949//FAD binding	"GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0070813//hydrogen sulfide metabolic process"	--
ENSG00000137770	10.23	7.72	7.696	6.844	5.616	6.981	797	633	489	407	435	449	CTDSPL2	CTD small phosphatase like 2 [Source:HGNC Symbol;Acc:HGNC:26936]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:0046827//positive regulation of protein export from nucleus	--
ENSG00000137776	12.782	9.562	7.841	5.384	8.183	10.329	788	661	411	290	475	516	SLTM	SAFB like transcription modulator [Source:HGNC Symbol;Acc:HGNC:20709]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0050684//regulation of mRNA processing	--
ENSG00000137801	12.064	10.678	10.174	4.195	5.246	6.474	1949	1734	1214	502	716	761	THBS1	thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Signal transduction;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Signaling molecules and interaction;Cell growth and death;Infectious disease: parasitic;Cancer: specific types	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04350//TGF-beta signaling pathway;ko04512//ECM-receptor interaction;ko04115//p53 signaling pathway;ko05144//Malaria;ko05219//Bladder cancer	K16857;K16857;K16857;K16857;K16857;K16857;K16857;K16857;K16857;K16857;K16857;K16857	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016529//sarcoplasmic reticulum;GO:0030141//secretory granule;GO:0031012//extracellular matrix;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0001968//fibronectin binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding;GO:0030169//low-density lipoprotein particle binding;GO:0042802//identical protein binding;GO:0043236//laminin binding;GO:0043394//proteoglycan binding;GO:0050431//transforming growth factor beta binding;GO:0050840//extracellular matrix binding;GO:0070051//fibrinogen binding;GO:0070052//collagen V binding	GO:0001666//response to hypoxia;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0002040//sprouting angiogenesis;GO:0002544//chronic inflammatory response;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006986//response to unfolded protein;GO:0007155//cell adhesion;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009749//response to glucose;GO:0010595//positive regulation of endothelial cell migration;GO:0010596//negative regulation of endothelial cell migration;GO:0010748//negative regulation of long-chain fatty acid import across plasma membrane;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0010757//negative regulation of plasminogen activation;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010763//positive regulation of fibroblast migration;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0018149//peptide cross-linking;GO:0030194//positive regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032026//response to magnesium ion;GO:0032570//response to progesterone;GO:0032695//negative regulation of interleukin-12 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0033574//response to testosterone;GO:0034605//cellular response to heat;GO:0034976//response to endoplasmic reticulum stress;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0043032//positive regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0043652//engulfment of apoptotic cell;GO:0045727//positive regulation of translation;GO:0045766//positive regulation of angiogenesis;GO:0048266//behavioral response to pain;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050921//positive regulation of chemotaxis;GO:0051592//response to calcium ion;GO:0051895//negative regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051918//negative regulation of fibrinolysis;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071636//positive regulation of transforming growth factor beta production;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903671//negative regulation of sprouting angiogenesis;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000137802	6.037	5.822	6.078	6.968	6.805	6.567	826	801	620	677	844	657	MAPKBP1	mitogen-activated protein kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29536]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0097431//mitotic spindle pole	GO:0005515//protein binding	GO:0032717//negative regulation of interleukin-8 production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:1900425//negative regulation of defense response to bacterium	--
ENSG00000137804	1.558	2.087	1.541	3.111	1.757	0.96	71	78	51	48	65	31.03	NUSAP1	nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0072686//mitotic spindle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000070//mitotic sister chromatid segregation;GO:0000226//microtubule cytoskeleton organization;GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0040001//establishment of mitotic spindle localization;GO:0045840//positive regulation of mitotic nuclear division;GO:0051301//cell division	--
ENSG00000137806	7.512	6.876	7.428	7.391	7.864	7.584	221	206	163	165	188	163	NDUFAF1	NADH:ubiquinone oxidoreductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:18828]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18159	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0005515//protein binding;GO:0051082//unfolded protein binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0010257//NADH dehydrogenase complex assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0051131//chaperone-mediated protein complex assembly;GO:0065003//protein-containing complex assembly"	--
ENSG00000137807	1.367	1.16	1.065	1.001	0.724	1.011	101	85	51	52	45	50	KIF23	kinesin family member 23 [Source:HGNC Symbol;Acc:HGNC:6392]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17387	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle;GO:0090543//Flemming body;GO:0097149//centralspindlin complex	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0000022//mitotic spindle elongation;GO:0000281//mitotic cytokinesis;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0032467//positive regulation of cytokinesis;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division	--
ENSG00000137809	22.537	24.197	6.38	4.388	9.239	4.935	4764	5141	996	687	1650	759	ITGA11	integrin subunit alpha 11 [Source:HGNC Symbol;Acc:HGNC:6136]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06587;K06587;K06587;K06587;K06587;K06587;K06587;K06587	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034681//integrin alpha11-beta1 complex	GO:0005178//integrin binding;GO:0005518//collagen binding;GO:0038064//collagen receptor activity;GO:0046872//metal ion binding;GO:0098639//collagen binding involved in cell-matrix adhesion	GO:0001649//osteoblast differentiation;GO:0006929//substrate-dependent cell migration;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007517//muscle organ development;GO:0033627//cell adhesion mediated by integrin;GO:0038065//collagen-activated signaling pathway;GO:0098609//cell-cell adhesion	--
ENSG00000137812	0.088	0.097	0.024	0.058	0.134	0.06	17	16.74	3	5	15	7	KNL1	kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031617//NMS complex"	GO:0005515//protein binding	GO:0001675//acrosome assembly;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0034501//protein localization to kinetochore;GO:0051301//cell division	--
ENSG00000137814	4.862	5.782	4.507	3.395	3.97	4.437	266	287	195	166	191	172	HAUS2	HAUS augmin like complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25530]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007020//microtubule nucleation;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0031023//microtubule organizing center organization;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000137815	15.882	13.577	14.157	8.148	6.939	7.354	930	997	613	387	576	493	RTF1	"RTF1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:28996]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016593//Cdc73/Paf1 complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:1990269//RNA polymerase II C-terminal domain phosphoserine binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001711//endodermal cell fate commitment;GO:0001832//blastocyst growth;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0019827//stem cell population maintenance;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation	--
ENSG00000137817	15.524	13.91	13.378	14.363	13.894	21.811	570	510	403	416	456	574	PARP6	poly(ADP-ribose) polymerase family member 6 [Source:HGNC Symbol;Acc:HGNC:26921]	-	-	-	-	-	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0006471//protein ADP-ribosylation;GO:0050775//positive regulation of dendrite morphogenesis;GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000137818	462.493	509.864	440.191	536.439	479.306	429.49	8698	8911	6145	7940	6926	5873	RPLP1	ribosomal protein lateral stalk subunit P1 [Source:HGNC Symbol;Acc:HGNC:10372]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02942;K02942	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0043021//ribonucleoprotein complex binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006414//translational elongation;GO:0032147//activation of protein kinase activity	--
ENSG00000137819	3.33	1.949	2.456	2.409	2.744	3.34	230	169	159	154	196	187	PAQR5	progestin and adipoQ receptor family member 5 [Source:HGNC Symbol;Acc:HGNC:29645]	Human Diseases	Cancer: overview	ko05207//Chemical carcinogenesis - receptor activation	K25041	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038023//signaling receptor activity	GO:0030154//cell differentiation;GO:0048477//oogenesis	--
ENSG00000137821	4.952	5.329	5.404	2.073	2.251	2.269	228	226	164	79	106	97	LRRC49	leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding	GO:0036158//outer dynein arm assembly	--
ENSG00000137822	7.753	7.62	6.924	5.276	6.554	7.829	856.42	796.9	592.79	463.12	663.19	612.34	TUBGCP4	tubulin gamma complex associated protein 4 [Source:HGNC Symbol;Acc:HGNC:16691]	-	-	-	-	GO:0000922//spindle pole;GO:0000923//equatorial microtubule organizing center;GO:0000930//gamma-tubulin complex;GO:0000931//gamma-tubulin large complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0055037//recycling endosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0031122//cytoplasmic microtubule organization;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle;GO:0065003//protein-containing complex assembly	--
ENSG00000137824	14.005	14.708	16.302	15.372	14.924	14.135	609	668	506	507	565	464	RMDN3	regulator of microtubule dynamics 3 [Source:HGNC Symbol;Acc:HGNC:25550]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044232//organelle membrane contact site;GO:0045171//intercellular bridge;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0006874//cellular calcium ion homeostasis;GO:0006915//apoptotic process;GO:0030154//cell differentiation	--
ENSG00000137825	0.026	0.026	0.077	0	0.031	0	1	1	1	0	1	0	ITPKA	inositol-trisphosphate 3-kinase A [Source:HGNC Symbol;Acc:HGNC:6178]	Metabolism;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00911;K00911;K00911;K00911	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043197//dendritic spine	"GO:0000166//nucleotide binding;GO:0000828//inositol hexakisphosphate kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding"	GO:0006020//inositol metabolic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048167//regulation of synaptic plasticity;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0097062//dendritic spine maintenance	--
ENSG00000137831	13.286	9.725	6.765	5.81	8.296	6.334	1476	1043	562	484	749	528	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats [Source:HGNC Symbol;Acc:HGNC:15947]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097190//apoptotic signaling pathway;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000137834	9.219	9.322	11.464	11.22	11.282	14.753	732	744	658	646	707	824	SMAD6	SMAD family member 6 [Source:HGNC Symbol;Acc:HGNC:6772]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K04677	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0071144//heteromeric SMAD protein complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070410//co-SMAD binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding;GO:0070698//type I activin receptor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0001657//ureteric bud development;GO:0003148//outflow tract septum morphogenesis;GO:0003170//heart valve development;GO:0003180//aortic valve morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003281//ventricular septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006955//immune response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007352//zygotic specification of dorsal/ventral axis;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0030154//cell differentiation;GO:0030279//negative regulation of ossification;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0031589//cell-substrate adhesion;GO:0032496//response to lipopolysaccharide;GO:0034616//response to laminar fluid shear stress;GO:0035904//aorta development;GO:0043066//negative regulation of apoptotic process;GO:0043627//response to estrogen;GO:0045444//fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060976//coronary vasculature development;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	MH1
ENSG00000137841	0.021	0	0	0	0.069	0.031	2	0	0	0	3	2	PLCB2	phospholipase C beta 2 [Source:HGNC Symbol;Acc:HGNC:9055]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Immune system;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Immune system;Immune system;Infectious disease: parasitic;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Sensory system;Digestive system;Endocrine system;Carbohydrate metabolism;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system;Excretory system;Digestive system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko00562//Inositol phosphate metabolism;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption"	K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031680//G-protein beta/gamma-subunit complex	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0046488//phosphatidylinositol metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050913//sensory perception of bitter taste	--
ENSG00000137842	5.626	6.409	6.888	6.699	5.945	6.68	294	303	249	207	226	190	TMEM62	transmembrane protein 62 [Source:HGNC Symbol;Acc:HGNC:26269]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity	-	--
ENSG00000137843	4.844	3.07	3.667	3.727	4.722	4.217	201	179	160	141	188	131	PAK6	p21 (RAC1) activated kinase 6 [Source:HGNC Symbol;Acc:HGNC:16061]	Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Cell motility;Infectious disease: viral;Cellular community - eukaryotes;Development and regeneration;Immune system;Signal transduction;Cancer: specific types	ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04510//Focal adhesion;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma	K05735;K05735;K05735;K05735;K05735;K05735;K05735;K05735	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0045296//cadherin binding;GO:0106310//protein serine kinase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007612//learning;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0140058//neuron projection arborization;GO:1990138//neuron projection extension"	--
ENSG00000137845	57.727	41.971	38.472	34.696	37.761	45.483	2626	1997	1419	1161	1544	1577	ADAM10	ADAM metallopeptidase domain 10 [Source:HGNC Symbol;Acc:HGNC:188]	Human Diseases;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial	ko05010//Alzheimer disease;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K06704;K06704	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0046930//pore complex;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0097038//perinuclear endoplasmic reticulum;GO:0097060//synaptic membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0098978//glutamatergic synapse	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:1902945//metalloendopeptidase activity involved in amyloid precursor protein catabolic process	GO:0001701//in utero embryonic development;GO:0006468//protein phosphorylation;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0007162//negative regulation of cell adhesion;GO:0007219//Notch signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008593//regulation of Notch signaling pathway;GO:0010629//negative regulation of gene expression;GO:0010820//positive regulation of T cell chemotaxis;GO:0016485//protein processing;GO:0022617//extracellular matrix disassembly;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0034332//adherens junction organization;GO:0034612//response to tumor necrosis factor;GO:0042117//monocyte activation;GO:0042987//amyloid precursor protein catabolic process;GO:0046931//pore complex assembly;GO:0051089//constitutive protein ectodomain proteolysis;GO:0090102//cochlea development;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0099173//postsynapse organization;GO:1901342//regulation of vasculature development;GO:1901998//toxin transport	--
ENSG00000137857	0.143	0.089	0.039	0.297	0.323	0.23	14	8	3	20	31	19	DUOX1	dual oxidase 1 [Source:HGNC Symbol;Acc:HGNC:3062]	Organismal Systems;Environmental Information Processing;Organismal Systems	Endocrine system;Signal transduction;Immune system	ko04918//Thyroid hormone synthesis;ko04013//MAPK signaling pathway - fly;ko04624//Toll and Imd signaling pathway	K13411;K13411;K13411	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031252//cell leading edge;GO:0043020//NADPH oxidase complex	GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050661//NADP binding;GO:0106293//NADH oxidase H202-forming activity;GO:0106294//NADPH oxidase H202-forming activity	GO:0006590//thyroid hormone generation;GO:0006952//defense response;GO:0006979//response to oxidative stress;GO:0019221//cytokine-mediated signaling pathway;GO:0042335//cuticle development;GO:0042446//hormone biosynthetic process;GO:0042554//superoxide anion generation;GO:0042744//hydrogen peroxide catabolic process;GO:0050665//hydrogen peroxide biosynthetic process;GO:0051591//response to cAMP;GO:0072593//reactive oxygen species metabolic process;GO:0090303//positive regulation of wound healing;GO:0098869//cellular oxidant detoxification;GO:2000147//positive regulation of cell motility	--
ENSG00000137860	0	0	0	0	0	0	0	0	0	0	0	0	SLC28A2	solute carrier family 28 member 2 [Source:HGNC Symbol;Acc:HGNC:11002]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030135//coated vesicle;GO:0031526//brush border membrane	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005337//nucleoside transmembrane transporter activity;GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005415//nucleoside:sodium symporter activity;GO:0015211//purine nucleoside transmembrane transporter activity;GO:0015213//uridine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015389//pyrimidine- and adenine-specific:sodium symporter activity;GO:1901474//azole transmembrane transporter activity	GO:0001895//retina homeostasis;GO:0006139//nucleobase-containing compound metabolic process;GO:0006836//neurotransmitter transport;GO:0015855//pyrimidine nucleobase transport;GO:0015860//purine nucleoside transmembrane transport;GO:0015862//uridine transport;GO:0032238//adenosine transport;GO:0035340//inosine transport;GO:0045117//azole transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1901642//nucleoside transmembrane transport;GO:1904823//purine nucleobase transmembrane transport	--
ENSG00000137868	26.706	28.033	30.944	39.766	37.827	35.649	1473	1539	1210	1605	1774	1354	STRA6	signaling receptor and transporter of retinol STRA6 [Source:HGNC Symbol;Acc:HGNC:30650]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0034632//retinol transmembrane transporter activity;GO:0038023//signaling receptor activity	GO:0001568//blood vessel development;GO:0001822//kidney development;GO:0003184//pulmonary valve morphogenesis;GO:0003281//ventricular septum development;GO:0007507//heart development;GO:0007612//learning;GO:0007631//feeding behavior;GO:0030324//lung development;GO:0030325//adrenal gland development;GO:0030540//female genitalia development;GO:0032526//response to retinoic acid;GO:0034633//retinol transport;GO:0042297//vocal learning;GO:0043010//camera-type eye development;GO:0043583//ear development;GO:0043585//nose morphogenesis;GO:0048286//lung alveolus development;GO:0048520//positive regulation of behavior;GO:0048546//digestive tract morphogenesis;GO:0048566//embryonic digestive tract development;GO:0048589//developmental growth;GO:0048745//smooth muscle tissue development;GO:0048844//artery morphogenesis;GO:0050890//cognition;GO:0050905//neuromuscular process;GO:0060322//head development;GO:0060323//head morphogenesis;GO:0060325//face morphogenesis;GO:0060426//lung vasculature development;GO:0060539//diaphragm development;GO:0060900//embryonic camera-type eye formation;GO:0061029//eyelid development in camera-type eye;GO:0061038//uterus morphogenesis;GO:0061143//alveolar primary septum development;GO:0061156//pulmonary artery morphogenesis;GO:0061205//paramesonephric duct development;GO:0071939//vitamin A import;GO:0097070//ductus arteriosus closure	--
ENSG00000137869	0.938	1.213	0.148	1.232	0.85	0.716	29	35	8	36	25	16	CYP19A1	cytochrome P450 family 19 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2594]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K07434;K07434;K07434	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0002677//negative regulation of chronic inflammatory response;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0006710//androgen catabolic process;GO:0006949//syncytium formation;GO:0008209//androgen metabolic process;GO:0008585//female gonad development;GO:0010760//negative regulation of macrophage chemotaxis;GO:0016125//sterol metabolic process;GO:0022900//electron transport chain;GO:0030540//female genitalia development;GO:0030879//mammary gland development;GO:0032355//response to estradiol;GO:0060065//uterus development;GO:0060736//prostate gland growth;GO:0061370//testosterone biosynthetic process;GO:2000866//positive regulation of estradiol secretion	--
ENSG00000137871	5.382	3.59	4.263	3.078	3.773	3.934	448.43	316.44	243.08	200.32	274.11	251	ZNF280D	zinc finger protein 280D [Source:HGNC Symbol;Acc:HGNC:25953]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Others
ENSG00000137872	5.406	6.305	7.386	6.418	6.796	7.738	653	724	595	500	641	646	SEMA6D	semaphorin 6D [Source:HGNC Symbol;Acc:HGNC:16770]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06842	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0014911//positive regulation of smooth muscle cell migration;GO:0014912//negative regulation of smooth muscle cell migration;GO:0021591//ventricular system development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000137875	0.077	0.252	0.052	0.261	0.137	0.212	2	5	1	5	3	4	BCL2L10	BCL2 like 10 [Source:HGNC Symbol;Acc:HGNC:993]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0089720//caspase binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000137876	24.902	22.975	24.117	19.546	18.696	26.295	904	812	635	518	562	672	RSL24D1	ribosomal L24 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18479]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02896;K02896	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000137877	0.058	0.086	0.151	0.095	0.102	0.113	14	21	27	17	21	20	SPTBN5	"spectrin beta, non-erythrocytic 5 [Source:HGNC Symbol;Acc:HGNC:15680]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005875//microtubule associated complex;GO:0008091//spectrin;GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0032391//photoreceptor connecting cilium;GO:0045179//apical cortex;GO:0097381//photoreceptor disc membrane	GO:0002046//opsin binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019894//kinesin binding;GO:0030507//spectrin binding;GO:0032029//myosin tail binding;GO:0034452//dynactin binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0045505//dynein intermediate chain binding;GO:0051015//actin filament binding	GO:0007030//Golgi organization;GO:0007041//lysosomal transport;GO:0030036//actin cytoskeleton organization;GO:0051693//actin filament capping	--
ENSG00000137878	0.08	0.243	0.187	0.075	0.114	0.227	8.36	10.98	7.18	4.06	4.55	8.82	GCOM1	"GCOM1, MYZAP-POLR2M combined locus [Source:HGNC Symbol;Acc:HGNC:26424]"	-	-	-	-	"GO:0005634//nucleus;GO:0016591//RNA polymerase II, holoenzyme"	-	GO:0035556//intracellular signal transduction	--
ENSG00000137880	6.879	7.862	11.881	11.414	7.571	8.409	103.58	119.17	132.32	127.49	96.45	92.26	GCHFR	GTP cyclohydrolase I feedback regulator [Source:HGNC Symbol;Acc:HGNC:4194]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0042470//melanosome	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0016597//amino acid binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030742//GTP-dependent protein binding;GO:0044549//GTP cyclohydrolase binding;GO:0044877//protein-containing complex binding	GO:0006809//nitric oxide biosynthetic process;GO:0009890//negative regulation of biosynthetic process;GO:0042133//neurotransmitter metabolic process;GO:0043105//negative regulation of GTP cyclohydrolase I activity;GO:0065003//protein-containing complex assembly	--
ENSG00000137936	13.891	14.704	15.45	12.943	14.669	19.445	878	928	724	611	791	885	BCAR3	"BCAR3 adaptor protein, NSP family member [Source:HGNC Symbol;Acc:HGNC:973]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction	GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019900//kinase binding	GO:0002089//lens morphogenesis in camera-type eye;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0009410//response to xenobiotic stimulus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0043547//positive regulation of GTPase activity;GO:0045740//positive regulation of DNA replication;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0086100//endothelin receptor signaling pathway	--
ENSG00000137941	2.249	1.521	1.22	1.406	1.292	1.191	285	166	118	107	160	117	TTLL7	tubulin tyrosine ligase like 7 [Source:HGNC Symbol;Acc:HGNC:26242]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0007399//nervous system development;GO:0018095//protein polyglutamylation;GO:0030154//cell differentiation	--
ENSG00000137942	22.402	19.118	17.19	11.861	14.316	15.015	2240	1921	1320	913	1255	1072	FNBP1L	formin binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:20851]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K20121	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0045296//cadherin binding;GO:0051020//GTPase binding	GO:0006897//endocytosis;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0010324//membrane invagination;GO:0016050//vesicle organization;GO:0030050//vesicle transport along actin filament;GO:0051491//positive regulation of filopodium assembly;GO:0060271//cilium assembly;GO:0072583//clathrin-dependent endocytosis;GO:0097320//plasma membrane tubulation	--
ENSG00000137944	17.209	16.47	16.036	13.7	13.029	15.337	595.78	591.66	415.72	355	397.33	402.75	KYAT3	kynurenine aminotransferase 3 [Source:HGNC Symbol;Acc:HGNC:33238]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00380//Tryptophan metabolism;ko00450//Selenocompound metabolism	K00816;K00816;K00816;K00816	GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0036137//kynurenine aminotransferase activity;GO:0042803//protein homodimerization activity;GO:0047315//kynurenine-glyoxylate transaminase activity;GO:0047804//cysteine-S-conjugate beta-lyase activity	GO:0006103//2-oxoglutarate metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0009058//biosynthetic process;GO:0070189//kynurenine metabolic process;GO:0097053//L-kynurenine catabolic process	--
ENSG00000137947	11.089	12.606	11.137	11.884	10.793	11.313	364	400	253	287	288	273	GTF2B	general transcription factor IIB [Source:HGNC Symbol;Acc:HGNC:4648]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Neurodegenerative disease;Transcription	ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko03022//Basal transcription factors	K03124;K03124;K03124	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:0097550//transcription preinitiation complex	GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0017025//TBP-class protein binding;GO:0046872//metal ion binding;GO:0046966//thyroid hormone receptor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding	"GO:0001174//transcriptional start site selection at RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006473//protein acetylation;GO:0016573//histone acetylation;GO:0019083//viral transcription;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0070897//transcription preinitiation complex assembly;GO:1904798//positive regulation of core promoter binding;GO:1990114//RNA polymerase II core complex assembly"	--
ENSG00000137948	0	0	0	0	0	0	0	0	0	0	0	0	BRDT	bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031493//nucleosomal histone binding;GO:0042393//histone binding;GO:0070577//lysine-acetylated histone binding;GO:0140566//epigenetic reader	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0043484//regulation of RNA splicing;GO:0051039//positive regulation of transcription involved in meiotic cell cycle;GO:0051321//meiotic cell cycle"	--
ENSG00000137955	34.698	32.161	31.331	31.636	32.519	35.247	1006	919	695	681	805	731	RABGGTB	Rab geranylgeranyltransferase subunit beta [Source:HGNC Symbol;Acc:HGNC:9796]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005968//Rab-protein geranylgeranyltransferase complex	GO:0003824//catalytic activity;GO:0004659//prenyltransferase activity;GO:0004663//Rab geranylgeranyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0006464//cellular protein modification process;GO:0007601//visual perception;GO:0018342//protein prenylation;GO:0018344//protein geranylgeranylation	--
ENSG00000137959	0.306	0.591	0.313	0.416	0.412	0.281	17	32	10	10	9	7	IFI44L	interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005525//GTP binding	GO:0006955//immune response;GO:0051607//defense response to virus	--
ENSG00000137960	0.051	0.013	0	0	0	0	4	1	0	0	0	0	GIPC2	GIPC PDZ domain containing family member 2 [Source:HGNC Symbol;Acc:HGNC:18177]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008150//biological_process	--
ENSG00000137962	3.845	3.095	2.493	2.519	2.459	2.557	481	375	225	218	232	231	ARHGAP29	Rho GTPase activating protein 29 [Source:HGNC Symbol;Acc:HGNC:30207]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000137965	0.143	0.428	0.646	0.415	0.462	0.249	5	15	8	8	12	5	IFI44	interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006955//immune response;GO:0009615//response to virus;GO:0009617//response to bacterium	--
ENSG00000137968	0.93	0.781	0.885	0.562	0.585	0.707	80	67	57	37	43	44	SLC44A5	solute carrier family 44 member 5 [Source:HGNC Symbol;Acc:HGNC:28524]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K15377	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015220//choline transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0015871//choline transport;GO:0055085//transmembrane transport	--
ENSG00000137975	0	0.012	0	0	0.044	0	0	1	0	0	3	0	CLCA2	chloride channel accessory 2 [Source:HGNC Symbol;Acc:HGNC:2016]	Organismal Systems;Organismal Systems	Digestive system;Endocrine system	ko04972//Pancreatic secretion;ko04924//Renin secretion	K05028;K05028	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031965//nuclear membrane	GO:0004222//metalloendopeptidase activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0015276//ligand-gated ion channel activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007155//cell adhesion;GO:0034220//ion transmembrane transport	--
ENSG00000137976	0	0	0	0	0	0	0	0	0	0	0	0	DNASE2B	deoxyribonuclease 2 beta [Source:HGNC Symbol;Acc:HGNC:28875]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K01158	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004531//deoxyribonuclease II activity;GO:0016787//hydrolase activity	GO:0006259//DNA metabolic process;GO:0006309//apoptotic DNA fragmentation	--
ENSG00000137992	6.207	5.649	5.563	5.474	4.98	6.157	587	468	392	328	344	322	DBT	dihydrolipoamide branched chain transacylase E2 [Source:HGNC Symbol;Acc:HGNC:2698]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism"	K09699;K09699;K09699	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex;GO:0015630//microtubule cytoskeleton;GO:0042645//mitochondrial nucleoid;GO:1990204//oxidoreductase complex	GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0031405//lipoic acid binding;GO:0031625//ubiquitin protein ligase binding;GO:0043754//dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	GO:0006082//organic acid metabolic process;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000137996	10.954	8.768	8.517	6.615	9.62	8.392	441	393	275	238	350	250	RTCA	RNA 3'-terminal phosphate cyclase [Source:HGNC Symbol;Acc:HGNC:17981]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0003963//RNA-3'-phosphate cyclase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006396//RNA processing	--
ENSG00000138002	9.531	10.414	11.233	10.566	12.421	10.802	1042	1168	929	860	1013	846	IFT172	intraflagellar transport 172 [Source:HGNC Symbol;Acc:HGNC:30391]	-	-	-	-	GO:0005929//cilium;GO:0005930//axoneme;GO:0030992//intraciliary transport particle B;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043227//membrane-bounded organelle;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097542//ciliary tip;GO:0097598//sperm cytoplasmic droplet;GO:1903561//extracellular vesicle	GO:0005515//protein binding	GO:0001841//neural tube formation;GO:0001843//neural tube closure;GO:0001947//heart looping;GO:0007219//Notch signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0007507//heart development;GO:0008544//epidermis development;GO:0008589//regulation of smoothened signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0016485//protein processing;GO:0021522//spinal cord motor neuron differentiation;GO:0021915//neural tube development;GO:0031122//cytoplasmic microtubule organization;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048596//embryonic camera-type eye morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060173//limb development;GO:0060271//cilium assembly;GO:0060348//bone development;GO:0061525//hindgut development;GO:0070986//left/right axis specification;GO:1905515//non-motile cilium assembly	--
ENSG00000138018	6.957	6.624	7.008	7.262	6.197	8.461	1164	1114	866	900	876	1030	SELENOI	selenoprotein I [Source:HGNC Symbol;Acc:HGNC:29361]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K00993;K00993;K00993;K00993	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004307//ethanolaminephosphotransferase activity;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000138028	0.35	0.753	0.48	0.563	0.401	0.345	14	27	11	16	13	7	CGREF1	cell growth regulator with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:16962]	-	-	-	-	GO:0005576//extracellular region	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation	--
ENSG00000138029	75.375	78.728	83.56	90.304	78.974	89.121	3075	3226	2519	2715	2715	2641	HADHB	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Lipid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00062//Fatty acid elongation"	K07509;K07509;K07509;K07509;K07509	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0042645//mitochondrial nucleoid	"GO:0003723//RNA binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0050633//acetyl-CoA C-myristoyltransferase activity;GO:0106222//long noncoding RNA binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0010467//gene expression;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000138030	1.901	1.494	1.576	1.824	1.041	1.786	81	63	55	67	44	65	KHK	ketohexokinase [Source:HGNC Symbol;Acc:HGNC:6315]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00051//Fructose and mannose metabolism	K00846;K00846	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004454//ketohexokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006000//fructose metabolic process;GO:0009744//response to sucrose;GO:0009749//response to glucose;GO:0009750//response to fructose;GO:0010043//response to zinc ion;GO:0016310//phosphorylation;GO:0032868//response to insulin;GO:0046835//carbohydrate phosphorylation;GO:0070873//regulation of glycogen metabolic process	--
ENSG00000138031	2.008	2.536	1.947	2.419	1.832	1.861	203.57	192.77	128.29	123.56	113.2	139	ADCY3	adenylate cyclase 3 [Source:HGNC Symbol;Acc:HGNC:234]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Global and overview maps;Cancer: overview;Sensory system;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system;Infectious disease: bacterial;Excretory system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko05110//Vibrio cholerae infection;ko04962//Vasopressin-regulated water reabsorption"	K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043;K08043	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding	GO:0002682//regulation of immune system process;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0003008//system process;GO:0006171//cAMP biosynthetic process;GO:0007165//signal transduction;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007338//single fertilization;GO:0007340//acrosome reaction;GO:0007608//sensory perception of smell;GO:0008355//olfactory learning;GO:0009190//cyclic nucleotide biosynthetic process;GO:0030317//flagellated sperm motility;GO:0035556//intracellular signal transduction;GO:0050896//response to stimulus;GO:0065008//regulation of biological quality;GO:1904322//cellular response to forskolin	--
ENSG00000138032	36.657	31.633	43.285	35.888	33.865	42.825	2329.72	2057	2083	1732	1863	2052	PPM1B	"protein phosphatase, Mg2+/Mn2+ dependent 1B [Source:HGNC Symbol;Acc:HGNC:9276]"	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04461	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030145//manganese ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0006499//N-terminal protein myristoylation;GO:0016311//dephosphorylation;GO:0032688//negative regulation of interferon-beta production;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050687//negative regulation of defense response to virus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000138035	5.549	5.326	24.351	4.037	3.664	4.912	388.12	329	224	199	236	257	PNPT1	polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K00962	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0042788//polysomal ribosome;GO:0045025//mitochondrial degradosome;GO:1902494//catalytic complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004654//polyribonucleotide nucleotidyltransferase activity;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0034046//poly(G) binding;GO:0035198//miRNA binding	"GO:0000957//mitochondrial RNA catabolic process;GO:0000958//mitochondrial mRNA catabolic process;GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0000964//mitochondrial RNA 5'-end processing;GO:0000965//mitochondrial RNA 3'-end processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006401//RNA catabolic process;GO:0006402//mRNA catabolic process;GO:0034599//cellular response to oxidative stress;GO:0035458//cellular response to interferon-beta;GO:0035927//RNA import into mitochondrion;GO:0035928//rRNA import into mitochondrion;GO:0043457//regulation of cellular respiration;GO:0043631//RNA polyadenylation;GO:0045926//negative regulation of growth;GO:0051252//regulation of RNA metabolic process;GO:0051260//protein homooligomerization;GO:0051591//response to cAMP;GO:0051726//regulation of cell cycle;GO:0060416//response to growth hormone;GO:0061014//positive regulation of mRNA catabolic process;GO:0070207//protein homotrimerization;GO:0070584//mitochondrion morphogenesis;GO:0071042//nuclear polyadenylation-dependent mRNA catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0097222//mitochondrial mRNA polyadenylation;GO:0097421//liver regeneration;GO:2000627//positive regulation of miRNA catabolic process;GO:2000772//regulation of cellular senescence"	--
ENSG00000138036	15.76	16.12	13.169	11.622	12.811	12.61	426	431	271	237	282	252	DYNC2LI1	dynein cytoplasmic 2 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:24595]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Excretory system	ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10417;K10417	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0097542//ciliary tip	GO:0005515//protein binding;GO:0045504//dynein heavy chain binding	GO:0007368//determination of left/right symmetry;GO:0030030//cell projection organization;GO:0035721//intraciliary retrograde transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0060271//cilium assembly;GO:1902017//regulation of cilium assembly	--
ENSG00000138039	0.031	0.025	0.048	0.251	0.158	0.212	2	1	2	10	8	7	LHCGR	luteinizing hormone/choriogonadotropin receptor [Source:HGNC Symbol;Acc:HGNC:6585]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04917//Prolactin signaling pathway;ko04913//Ovarian steroidogenesis	K04248;K04248;K04248;K04248;K04248	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004964//luteinizing hormone receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity;GO:0035472//choriogonadotropin hormone receptor activity;GO:0038106//choriogonadotropin hormone binding	"GO:0001541//ovarian follicle development;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008584//male gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0022602//ovulation cycle process;GO:0030539//male genitalia development;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0042700//luteinizing hormone signaling pathway;GO:0050890//cognition;GO:0071371//cellular response to gonadotropin stimulus;GO:0071373//cellular response to luteinizing hormone stimulus"	--
ENSG00000138050	1.809	1.542	1.255	1.702	1.118	1.734	70	65	42	49	38	49	THUMPD2	THUMP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:14890]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016423//tRNA (guanine) methyltransferase activity;GO:0016740//transferase activity	GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000138061	19.514	16.84	16.463	19.222	17.421	16.483	2112	1832	1316	1541	1593	1298	CYP1B1	cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597]	Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Metabolism;Organismal Systems;Metabolism	Cancer: overview;Cancer: overview;Cancer: overview;Xenobiotics biodegradation and metabolism;Cancer: overview;Lipid metabolism;Endocrine system;Amino acid metabolism	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis;ko00380//Tryptophan metabolism	K07410;K07410;K07410;K07410;K07410;K07410;K07410;K07410	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016829//lyase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0001525//angiogenesis;GO:0002930//trabecular meshwork development;GO:0006304//DNA modification;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006725//cellular aromatic compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0007155//cell adhesion;GO:0007584//response to nutrient;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0009404//toxin metabolic process;GO:0009636//response to toxic substance;GO:0010033//response to organic substance;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0014070//response to organic cyclic compound;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016125//sterol metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0030199//collagen fibril organization;GO:0030325//adrenal gland development;GO:0030336//negative regulation of cell migration;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032354//response to follicle-stimulating hormone;GO:0032355//response to estradiol;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0042537//benzene-containing compound metabolic process;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043542//endothelial cell migration;GO:0044849//estrous cycle;GO:0045727//positive regulation of translation;GO:0045766//positive regulation of angiogenesis;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046466//membrane lipid catabolic process;GO:0046685//response to arsenic-containing substance;GO:0048514//blood vessel morphogenesis;GO:0048545//response to steroid hormone;GO:0061298//retina vasculature development in camera-type eye;GO:0061304//retinal blood vessel morphogenesis;GO:0061548//ganglion development;GO:0070301//cellular response to hydrogen peroxide;GO:0071320//cellular response to cAMP;GO:0071356//cellular response to tumor necrosis factor;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0071387//cellular response to cortisol stimulus;GO:0071393//cellular response to progesterone stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071548//response to dexamethasone;GO:0071603//endothelial cell-cell adhesion;GO:0071680//response to indole-3-methanol;GO:0097267//omega-hydroxylase P450 pathway;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000138068	0	0	0	0	0.069	0	0	0	0	0	1	0	SULT6B1	sulfotransferase family 6B member 1 [Source:HGNC Symbol;Acc:HGNC:33433]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000138069	94.283	83.74	89.47	88.766	85.65	102.912	4041	3687	2848	2702	3165	3229	RAB1A	"RAB1A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9758]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05130//Pathogenic Escherichia coli infection;ko04140//Autophagy - animal;ko05134//Legionellosis	K07874;K07874;K07874;K07874;K07874	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030658//transport vesicle membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0045296//cadherin binding	GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016477//cell migration;GO:0019068//virion assembly;GO:0030252//growth hormone secretion;GO:0032402//melanosome transport;GO:0032757//positive regulation of interleukin-8 production;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042742//defense response to bacterium;GO:0047496//vesicle transport along microtubule;GO:0090110//COPII-coated vesicle cargo loading;GO:1903020//positive regulation of glycoprotein metabolic process	--
ENSG00000138071	70.27	64.077	63.544	56.24	55.861	56.613	5052	4558	3374	2913	3290	3010	ACTR2	actin related protein 2 [Source:HGNC Symbol;Acc:HGNC:169]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K17260;K17260;K17260;K17260;K17260;K17260;K17260;K17260;K17260	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030478//actin cap;GO:0035578//azurophil granule lumen;GO:0035861//site of double-strand break;GO:0042995//cell projection;GO:0061825//podosome core;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0051015//actin filament binding	GO:0007163//establishment or maintenance of cell polarity;GO:0008306//associative learning;GO:0008356//asymmetric cell division;GO:0010592//positive regulation of lamellipodium assembly;GO:0016344//meiotic chromosome movement towards spindle pole;GO:0016482//cytosolic transport;GO:0030036//actin cytoskeleton organization;GO:0033206//meiotic cytokinesis;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0035902//response to immobilization stress;GO:0035984//cellular response to trichostatin A;GO:0045471//response to ethanol;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051321//meiotic cell cycle;GO:0051653//spindle localization;GO:0060271//cilium assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071346//cellular response to interferon-gamma;GO:1905168//positive regulation of double-strand break repair via homologous recombination	--
ENSG00000138073	22.312	22.337	23.947	22.251	20.918	24.549	958	971	766	714	773	784	PREB	prolactin regulatory element binding [Source:HGNC Symbol;Acc:HGNC:9356]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14003	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0070971//endoplasmic reticulum exit site	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0051020//GTPase binding	GO:0003400//regulation of COPII vesicle coating;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032527//protein exit from endoplasmic reticulum;GO:0048208//COPII vesicle coating;GO:0050790//regulation of catalytic activity	Others
ENSG00000138074	67.828	76.079	92.018	108.368	108.769	105.665	3313.71	3541.35	3164	4137.33	4215.44	4048.36	SLC5A6	solute carrier family 5 member 6 [Source:HGNC Symbol;Acc:HGNC:11041]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14386	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	GO:0005515//protein binding;GO:0008523//sodium-dependent multivitamin transmembrane transporter activity;GO:0015225//biotin transmembrane transporter activity;GO:0015233//pantothenate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0090482//vitamin transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0015878//biotin transport;GO:0015887//pantothenate transmembrane transport;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1904200//iodide transmembrane transport;GO:1905135//biotin import across plasma membrane	--
ENSG00000138075	0	0	0	0	0	0	0	0	0	0	0	0	ABCG5	ATP binding cassette subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:13886]	Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems	Digestive system;Digestive system;Membrane transport;Digestive system	ko04976//Bile secretion;ko04979//Cholesterol metabolism;ko02010//ABC transporters;ko04975//Fat digestion and absorption	K05683;K05683;K05683;K05683	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0043235//receptor complex;GO:0045177//apical part of cell	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0120020//cholesterol transfer activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0010212//response to ionizing radiation;GO:0010949//negative regulation of intestinal phytosterol absorption;GO:0014850//response to muscle activity;GO:0015918//sterol transport;GO:0030299//intestinal cholesterol absorption;GO:0031667//response to nutrient levels;GO:0033344//cholesterol efflux;GO:0038183//bile acid signaling pathway;GO:0042632//cholesterol homeostasis;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0055085//transmembrane transport;GO:0070328//triglyceride homeostasis;GO:0120009//intermembrane lipid transfer	--
ENSG00000138078	54.606	47.072	47.814	39.156	42.336	48.831	5124.31	4497.2	3330.56	2682.57	3349.13	3353.57	PREPL	prolyl endopeptidase like [Source:HGNC Symbol;Acc:HGNC:30228]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0006508//proteolysis;GO:0042147//retrograde transport, endosome to Golgi;GO:0043001//Golgi to plasma membrane protein transport;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000138079	0.301	0.205	0.342	0.383	0.324	0.435	10.02	6.8	15.44	17.43	16.87	16.43	SLC3A1	solute carrier family 3 member 1 [Source:HGNC Symbol;Acc:HGNC:11025]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14210	GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity	GO:0005975//carbohydrate metabolic process;GO:0006865//amino acid transport;GO:0010467//gene expression;GO:0015802//basic amino acid transport;GO:0015810//aspartate transmembrane transport;GO:0015811//L-cystine transport;GO:0015813//L-glutamate transmembrane transport;GO:1990822//basic amino acid transmembrane transport	--
ENSG00000138080	0.88	0.945	0.671	0.341	0.621	0.392	71	70	40	18	38	23	EMILIN1	elastin microfibril interfacer 1 [Source:HGNC Symbol;Acc:HGNC:19880]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0034668//integrin alpha4-beta1 complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1990971//EMILIN complex	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0042802//identical protein binding;GO:0098640//integrin binding involved in cell-matrix adhesion	GO:0003180//aortic valve morphogenesis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0008217//regulation of blood pressure;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010811//positive regulation of cell-substrate adhesion;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030194//positive regulation of blood coagulation;GO:0030198//extracellular matrix organization;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032966//negative regulation of collagen biosynthetic process;GO:0033627//cell adhesion mediated by integrin;GO:0042127//regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0048251//elastic fiber assembly;GO:0050866//negative regulation of cell activation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1900426//positive regulation of defense response to bacterium;GO:1901203//positive regulation of extracellular matrix assembly;GO:1901731//positive regulation of platelet aggregation;GO:1904027//negative regulation of collagen fibril organization;GO:1905522//negative regulation of macrophage migration	--
ENSG00000138081	19.485	14.083	15.203	12.726	13.405	15.311	1469.93	1185.54	929.78	766.52	913.03	922.35	FBXO11	F-box protein 11 [Source:HGNC Symbol;Acc:HGNC:13590]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016274//protein-arginine N-methyltransferase activity;GO:0046872//metal ion binding	GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007605//sensory perception of sound;GO:0016567//protein ubiquitination;GO:0035246//peptidyl-arginine N-methylation;GO:0042981//regulation of apoptotic process	--
ENSG00000138083	28.024	25.706	32.867	34.258	32.876	38.247	1577	1454	1366	1428	1563	1566	SIX3	SIX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:10889]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001654//eye development;GO:0002070//epithelial cell maturation;GO:0002088//lens development in camera-type eye;GO:0003404//optic vesicle morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007601//visual perception;GO:0009946//proximal/distal axis specification;GO:0014016//neuroblast differentiation;GO:0021537//telencephalon development;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021846//cell proliferation in forebrain;GO:0021978//telencephalon regionalization;GO:0021983//pituitary gland development;GO:0042127//regulation of cell population proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061074//regulation of neural retina development;GO:0070306//lens fiber cell differentiation;GO:0097402//neuroblast migration;GO:1901987//regulation of cell cycle phase transition;GO:1902692//regulation of neuroblast proliferation;GO:1902742//apoptotic process involved in development;GO:1990086//lens fiber cell apoptotic process;GO:2000177//regulation of neural precursor cell proliferation"	Homeobox
ENSG00000138085	89.46	94.825	97.401	99.066	90.759	97.505	2214.29	2344.65	1780	1806.67	1891.56	1743.64	ATRAID	all-trans retinoic acid induced differentiation factor [Source:HGNC Symbol;Acc:HGNC:24090]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0033689//negative regulation of osteoblast proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:1903363//negative regulation of cellular protein catabolic process	--
ENSG00000138092	2.206	2.363	2.572	2.354	2.176	2.409	191.59	204.4	165.04	153.12	160.03	151.1	CENPO	centromere protein O [Source:HGNC Symbol;Acc:HGNC:28152]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031511//Mis6-Sim4 complex"	GO:0005515//protein binding	GO:0034508//centromere complex assembly	--
ENSG00000138095	32.804	26.084	26.896	23.653	24.798	24.035	3313	2666	2050	1741	2154	1833	LRPPRC	leucine rich pentatricopeptide repeat containing [Source:HGNC Symbol;Acc:HGNC:15714]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0048471//perinuclear region of cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding;GO:0048487//beta-tubulin binding	GO:0000961//negative regulation of mitochondrial RNA catabolic process;GO:0047497//mitochondrion transport along microtubule;GO:0051028//mRNA transport;GO:0070129//regulation of mitochondrial translation	--
ENSG00000138100	0	0	0	0	0	0	0	0	0	0	0	0	TRIM54	tripartite motif containing 54 [Source:HGNC Symbol;Acc:HGNC:16008]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0030018//Z disc	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007017//microtubule-based process;GO:0007026//negative regulation of microtubule depolymerization;GO:0007165//signal transduction;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation	--
ENSG00000138101	5.25	5.77	5.799	4.762	5.877	4.2	258	283	211	174	246	150	DTNB	dystrobrevin beta [Source:HGNC Symbol;Acc:HGNC:3058]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0060077//inhibitory synapse;GO:0098794//postsynapse	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0030182//neuron differentiation;GO:0099536//synaptic signaling	--
ENSG00000138107	58.893	62.897	60.918	64.189	59.662	66.518	3457	3711	2641	2791	2958	2841	ACTR1A	actin related protein 1A [Source:HGNC Symbol;Acc:HGNC:167]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection	K16575;K16575;K16575;K16575	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0005875//microtubule associated complex;GO:0005938//cell cortex;GO:0015630//microtubule cytoskeleton;GO:0070062//extracellular exosome;GO:0099738//cell cortex region	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0016192//vesicle-mediated transport	--
ENSG00000138109	0	0	0	0	0	0	0	0	0	0	0	0	CYP2C9	cytochrome P450 family 2 subfamily C member 9 [Source:HGNC Symbol;Acc:HGNC:2623]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Nervous system;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko04726//Serotonergic synapse;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism;ko00591//Linoleic acid metabolism	K17719;K17719;K17719;K17719;K17719;K17719;K17719;K17719;K17719	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0008404//arachidonic acid 14,15-epoxygenase activity;GO:0008405//arachidonic acid 11,12-epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0018675//(S)-limonene 6-monooxygenase activity;GO:0018676//(S)-limonene 7-monooxygenase activity;GO:0020037//heme binding;GO:0034875//caffeine oxidase activity;GO:0046872//metal ion binding;GO:0052741//(R)-limonene 6-monooxygenase activity;GO:0070330//aromatase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008210//estrogen metabolic process;GO:0016098//monoterpenoid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0019627//urea metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0042178//xenobiotic catabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0043603//cellular amide metabolic process;GO:0046456//icosanoid biosynthetic process;GO:0070989//oxidative demethylation;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000138111	0.389	0.539	0.183	0.525	0.38	0.593	23	17	8	23	19	22	MFSD13A	major facilitator superfamily domain containing 13A [Source:HGNC Symbol;Acc:HGNC:26196]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000138115	0.258	0.051	0.068	0.156	0.074	0.125	10	2	2	3	2	3	CYP2C8	cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]	Metabolism;Human Diseases;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Nervous system;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko04726//Serotonergic synapse;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism;ko00591//Linoleic acid metabolism	K17718;K17718;K17718;K17718;K17718;K17718;K17718;K17718	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0034875//caffeine oxidase activity;GO:0046872//metal ion binding;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity"	GO:0002933//lipid hydroxylation;GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042178//xenobiotic catabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0046456//icosanoid biosynthetic process;GO:0070989//oxidative demethylation;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000138119	17.899	19.398	13.854	12.495	12.192	11.285	2485	2704	1431	1286	1410	1135	MYOF	myoferlin [Source:HGNC Symbol;Acc:HGNC:3656]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0001778//plasma membrane repair;GO:0006936//muscle contraction;GO:0007009//plasma membrane organization;GO:0007520//myoblast fusion;GO:0008015//blood circulation;GO:0033292//T-tubule organization;GO:0061025//membrane fusion	--
ENSG00000138131	4.624	5.014	3.702	2.153	2.364	2.192	345	376	204	119	149	119	LOXL4	lysyl oxidase like 4 [Source:HGNC Symbol;Acc:HGNC:17171]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	"GO:0004720//protein-lysine 6-oxidase activity;GO:0005044//scavenger receptor activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046872//metal ion binding"	GO:0006897//endocytosis;GO:0018057//peptidyl-lysine oxidation;GO:0030199//collagen fibril organization	--
ENSG00000138134	0.62	0.771	0.529	0.805	0.819	0.656	26	34	18	25	29	20	STAMBPL1	STAM binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:24105]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0070536//protein K63-linked deubiquitination	--
ENSG00000138135	0	0	0	0	0	0	0	0	0	0	0	0	CH25H	cholesterol 25-hydroxylase [Source:HGNC Symbol;Acc:HGNC:1907]	Metabolism	Lipid metabolism	ko00120//Primary bile acid biosynthesis	K10223	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000254//C-4 methylsterol oxidase activity;GO:0001567//cholesterol 25-hydroxylase activity;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008610//lipid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0034340//response to type I interferon;GO:0035754//B cell chemotaxis;GO:1903914//negative regulation of fusion of virus membrane with host plasma membrane	--
ENSG00000138136	0	0	0	0	0	0	0	0	0	0	0	0	LBX1	ladybird homeobox 1 [Source:HGNC Symbol;Acc:HGNC:16960]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001947//heart looping;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0021522//spinal cord motor neuron differentiation;GO:0030154//cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0048663//neuron fate commitment;GO:0048664//neuron fate determination"	Homeobox
ENSG00000138138	28.583	24.31	25.861	22.711	23.567	27.302	2000	1672	1327	1184	1395	1352	ATAD1	ATPase family AAA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25903]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0140567//transmembrane protein dislocase activity	"GO:0002092//positive regulation of receptor internalization;GO:0007612//learning;GO:0007613//memory;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0140570//extraction of mislocalized protein from mitochondrial outer membrane"	--
ENSG00000138152	0	0	0	0	0	0	0	0	0	0	0	0	BTBD16	BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:26340]	-	-	-	-	-	-	-	--
ENSG00000138160	1.547	1.033	0.972	0.571	0.785	0.987	161	108	74	44	69	74	KIF11	kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0019901//protein kinase binding	GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007052//mitotic spindle organization;GO:0007100//mitotic centrosome separation;GO:0046602//regulation of mitotic centrosome separation;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0090307//mitotic spindle assembly	--
ENSG00000138161	0	0.035	0	0	0.029	0	0	1	0	0	1	0	CUZD1	CUB and zona pellucida like domains 1 [Source:HGNC Symbol;Acc:HGNC:17937]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042589//zymogen granule membrane	-	GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0032023//trypsinogen activation;GO:0051301//cell division	--
ENSG00000138162	4.92	4.826	5.15	4.673	5.153	4.499	454	476	359	375	418	336	TACC2	transforming acidic coiled-coil containing protein 2 [Source:HGNC Symbol;Acc:HGNC:11523]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	GO:0016922//nuclear receptor binding	GO:0000226//microtubule cytoskeleton organization;GO:0007052//mitotic spindle organization;GO:0008283//cell population proliferation;GO:0021987//cerebral cortex development	--
ENSG00000138166	0.292	0.194	0.184	0.236	0.207	0.134	15	10	7	9	9	5	DUSP5	dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0001706//endoderm formation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0070371//ERK1 and ERK2 cascade	--
ENSG00000138172	1.992	1.687	1.975	2.405	2.565	2.105	77	66	56	69	83	59	CALHM2	calcium homeostasis modulator family member 2 [Source:HGNC Symbol;Acc:HGNC:23493]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005261//cation channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0043065//positive regulation of apoptotic process;GO:0098655//cation transmembrane transport	--
ENSG00000138175	10.563	9.595	10.284	9.133	8.633	9.263	840	767	604	538	580	536	ARL3	ADP ribosylation factor like GTPase 3 [Source:HGNC Symbol;Acc:HGNC:694]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0019003//GDP binding;GO:0032794//GTPase activating protein binding;GO:0046872//metal ion binding	GO:0000281//mitotic cytokinesis;GO:0001822//kidney development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006893//Golgi to plasma membrane transport;GO:0007049//cell cycle;GO:0007224//smoothened signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0042073//intraciliary transport;GO:0042461//photoreceptor cell development;GO:0051301//cell division;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1903441//protein localization to ciliary membrane	--
ENSG00000138180	0.29	0.672	0.442	0.269	0.279	0.324	16	23	18	11	13	13	CEP55	centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0045171//intercellular bridge;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0045184//establishment of protein localization;GO:0051301//cell division;GO:0061952//midbody abscission;GO:1904888//cranial skeletal system development	--
ENSG00000138182	0.474	0.32	0.186	0.188	0.345	0.828	62	36	18	13	23	24	KIF20B	kinesin family member 20B [Source:HGNC Symbol;Acc:HGNC:7212]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030424//axon;GO:0030426//growth cone;GO:0030496//midbody;GO:0042995//cell projection;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0051233//spindle midzone;GO:0070938//contractile ring;GO:0097431//mitotic spindle pole;GO:1990023//mitotic spindle midzone	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0042803//protein homodimerization activity;GO:0050699//WW domain binding	GO:0001843//neural tube closure;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0008284//positive regulation of cell population proliferation;GO:0032467//positive regulation of cytokinesis;GO:0035372//protein localization to microtubule;GO:0048812//neuron projection morphogenesis;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0070201//regulation of establishment of protein localization;GO:0090316//positive regulation of intracellular protein transport;GO:1903438//positive regulation of mitotic cytokinetic process;GO:2000114//regulation of establishment of cell polarity;GO:2001222//regulation of neuron migration;GO:2001224//positive regulation of neuron migration	--
ENSG00000138185	1.845	1.859	1.934	1.883	1.256	1.362	419	379	303	230	275	233	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3363]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Infectious disease: viral;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko05169//Epstein-Barr virus infection;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01510;K01510;K01510;K01510	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:0102485//dATP phosphohydrolase activity;GO:0102486//dCTP phosphohydrolase activity;GO:0102487//dUTP phosphohydrolase activity;GO:0102488//dTTP phosphohydrolase activity;GO:0102489//GTP phosphohydrolase activity;GO:0102490//8-oxo-dGTP phosphohydrolase activity;GO:0102491//dGTP phosphohydrolase activity	GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0009134//nucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process	--
ENSG00000138190	8.342	2.137	2.44	2.447	3.004	2.507	238	158	130	134	172	129	EXOC6	exocyst complex component 6 [Source:HGNC Symbol;Acc:HGNC:23196]	-	-	-	-	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030426//growth cone;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0090543//Flemming body	GO:0005515//protein binding	GO:0000281//mitotic cytokinesis;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000138193	39.271	30.84	32.373	25.093	28.79	32.035	5936	4677	3572	2849	3609	3440	PLCE1	phospholipase C epsilon 1 [Source:HGNC Symbol;Acc:HGNC:17175]	Metabolism;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Endocrine system;Endocrine and metabolic disease;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04919//Thyroid hormone signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K05860;K05860;K05860;K05860;K05860;K05860;K05860;K05860;K05860;K05860;K05860	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0001558//regulation of cell growth;GO:0006629//lipid metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0006940//regulation of smooth muscle contraction;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007507//heart development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010592//positive regulation of lamellipodium assembly;GO:0016042//lipid catabolic process;GO:0019722//calcium-mediated signaling;GO:0032835//glomerulus development;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0045859//regulation of protein kinase activity;GO:0046578//regulation of Ras protein signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048016//inositol phosphate-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000138207	0	0	0	0	0.302	0	0	0	0	0	5	0	RBP4	retinol binding protein 4 [Source:HGNC Symbol;Acc:HGNC:9922]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005501//retinoid binding;GO:0005515//protein binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0034632//retinol transmembrane transporter activity	GO:0001654//eye development;GO:0002639//positive regulation of immunoglobulin production;GO:0006094//gluconeogenesis;GO:0007507//heart development;GO:0007601//visual perception;GO:0030277//maintenance of gastrointestinal epithelium;GO:0030324//lung development;GO:0032024//positive regulation of insulin secretion;GO:0032526//response to retinoic acid;GO:0034633//retinol transport;GO:0042572//retinol metabolic process;GO:0042593//glucose homeostasis;GO:0048562//embryonic organ morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048738//cardiac muscle tissue development;GO:0048807//female genitalia morphogenesis;GO:0050896//response to stimulus;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0060065//uterus development;GO:0060068//vagina development;GO:0060157//urinary bladder development;GO:0060347//heart trabecula formation	--
ENSG00000138231	6.484	5.46	5.812	4.352	4.888	5.302	358	303	237	178	228	213	DBR1	debranching RNA lariats 1 [Source:HGNC Symbol;Acc:HGNC:15594]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0003723//RNA binding;GO:0008419//RNA lariat debranching enzyme activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000138246	7.14	4.761	4.533	4.172	5.074	5.188	1123	765	498	497	663	607	DNAJC13	DnaJ heat shock protein family (Hsp40) member C13 [Source:HGNC Symbol;Acc:HGNC:30343]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0031901//early endosome membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0071203//WASH complex	GO:0005515//protein binding	GO:0001649//osteoblast differentiation;GO:0006898//receptor-mediated endocytosis;GO:0007032//endosome organization;GO:0015031//protein transport;GO:1902954//regulation of early endosome to recycling endosome transport;GO:2000641//regulation of early endosome to late endosome transport	--
ENSG00000138271	0	0	0	0	0	0	0	0	0	0	0	0	GPR87	G protein-coupled receptor 87 [Source:HGNC Symbol;Acc:HGNC:4538]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008150//biological_process;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway	--
ENSG00000138279	29.252	28.796	28.065	28.006	30.244	27.496	1446	1466	1049	1041	1242	1010	ANXA7	annexin A7 [Source:HGNC Symbol;Acc:HGNC:545]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K17095	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0042584//chromaffin granule membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0048306//calcium-dependent protein binding	GO:0006914//autophagy;GO:0010629//negative regulation of gene expression;GO:0030855//epithelial cell differentiation	--
ENSG00000138286	8.499	8.071	7.506	7.042	6.649	7.97	443.31	392.56	273.52	269.11	269.13	286.52	FAM149B1	family with sequence similarity 149 member B1 [Source:HGNC Symbol;Acc:HGNC:29162]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium	--
ENSG00000138303	13.838	16.83	13.284	11.44	13.058	14.178	501	564	419.03	330	427	366	ASCC1	activating signal cointegrator 1 complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24268]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016607//nuclear speck;GO:0031594//neuromuscular junction	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus"	--
ENSG00000138308	0.031	0	0	0	0	0	1	0	0	0	0	0	PLA2G12B	phospholipase A2 group XIIB [Source:HGNC Symbol;Acc:HGNC:18555]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006644//phospholipid metabolic process;GO:0016042//lipid catabolic process;GO:0042632//cholesterol homeostasis;GO:0050482//arachidonic acid secretion;GO:0070328//triglyceride homeostasis	--
ENSG00000138311	1.067	1.057	0.913	1.038	0.94	0.968	66	74	53	53	61	45	ZNF365	zinc finger protein 365 [Source:HGNC Symbol;Acc:HGNC:18194]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0000723//telomere maintenance;GO:0007399//nervous system development;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010975//regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0021687//cerebellar molecular layer morphogenesis;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0060997//dendritic spine morphogenesis;GO:0110026//regulation of DNA strand resection involved in replication fork processing;GO:0140059//dendrite arborization	--
ENSG00000138315	0	0	0	0	0	0	0	0	0	0	0	0	OIT3	oncoprotein induced transcript 3 [Source:HGNC Symbol;Acc:HGNC:29953]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0009986//cell surface	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:1903118//urate homeostasis	--
ENSG00000138316	0.046	0	0.035	0.086	0.092	0.013	5	0	3	7	9	1	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif 14 [Source:HGNC Symbol;Acc:HGNC:14899]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process	--
ENSG00000138326	550.99	615.039	559.588	486.073	450.685	450.394	6131	6884	4600	4008	4243	3652	RPS24	ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:10411]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02974;K02974	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0031369//translation initiation factor binding	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0034101//erythrocyte homeostasis;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000138336	0.998	0.749	0.645	0.481	0.552	0.358	199	150	95	71	93	52	TET1	tet methylcytosine dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:29484]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0016580//Sin3 complex	GO:0003677//DNA binding;GO:0005506//iron ion binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0070579//methylcytosine dioxygenase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001826//inner cell mass cell differentiation;GO:0006211//5-methylcytosine catabolic process;GO:0006325//chromatin organization;GO:0006493//protein O-linked glycosylation;GO:0008284//positive regulation of cell population proliferation;GO:0019827//stem cell population maintenance;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031062//positive regulation of histone methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:0090310//negative regulation of DNA methylation-dependent heterochromatin assembly;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance	--
ENSG00000138346	0.338	0.32	0.363	0.214	0.372	0.273	28	26	21	14	24	16	DNA2	DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K10742	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005760//gamma DNA polymerase complex;GO:0042645//mitochondrial nucleoid"	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0016890//site-specific endodeoxyribonuclease activity, specific for altered base;GO:0017108//5'-flap endonuclease activity;GO:0017116//single-stranded DNA helicase activity;GO:0043139//5'-3' DNA helicase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0000076//DNA replication checkpoint signaling;GO:0000723//telomere maintenance;GO:0000729//DNA double-strand break processing;GO:0006260//DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0032201//telomere maintenance via semi-conservative replication;GO:0032508//DNA duplex unwinding;GO:0033567//DNA replication, Okazaki fragment processing;GO:0043137//DNA replication, removal of RNA primer;GO:0043504//mitochondrial DNA repair;GO:0044806//G-quadruplex DNA unwinding;GO:0045740//positive regulation of DNA replication;GO:0071932//replication fork reversal;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090656//t-circle formation;GO:1902990//mitotic telomere maintenance via semi-conservative replication"	--
ENSG00000138347	0	0.01	0	0	0.012	0	0	1	0	0	1	0	MYPN	myopalladin [Source:HGNC Symbol;Acc:HGNC:23246]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030424//axon;GO:0031674//I band	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0017124//SH3 domain binding;GO:0051371//muscle alpha-actinin binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0045214//sarcomere organization;GO:0070593//dendrite self-avoidance	--
ENSG00000138356	0.521	0.253	0.662	0.453	0.301	0.323	30	26	29	22	26	24	AOX1	aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko04630//JAK-STAT signaling pathway;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00280//Valine, leucine and isoleucine degradation;ko00380//Tryptophan metabolism;ko00350//Tyrosine metabolism;ko00760//Nicotinate and nicotinamide metabolism;ko00750//Vitamin B6 metabolism"	K00157;K00157;K00157;K00157;K00157;K00157;K00157;K00157;K00157	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004031//aldehyde oxidase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043546//molybdopterin cofactor binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051287//NAD binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0071949//FAD binding;GO:0102797//geranial:oxygen oxidoreductase activity;GO:0102798//heptaldehyde:oxygen oxidoreductase activity"	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000138363	38.883	36.026	39.039	40.146	37.635	42.45	1594	1500	1192	1244	1288	1257	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:794]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Nucleotide metabolism;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko01523//Antifolate resistance;ko00670//One carbon pool by folate	K00602;K00602;K00602;K00602	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0003937//IMP cyclohydrolase activity;GO:0004643//phosphoribosylaminoimidazolecarboxamide formyltransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0003360//brainstem development;GO:0006139//nucleobase-containing compound metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0008152//metabolic process;GO:0009116//nucleoside metabolic process;GO:0009259//ribonucleotide metabolic process;GO:0010035//response to inorganic substance;GO:0021549//cerebellum development;GO:0021987//cerebral cortex development;GO:0031100//animal organ regeneration;GO:0044208//'de novo' AMP biosynthetic process;GO:0046452//dihydrofolate metabolic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0097294//'de novo' XMP biosynthetic process;GO:0098761//cellular response to interleukin-7	--
ENSG00000138375	10.098	9.16	10.415	7.644	11.042	10.782	592	553	425	348	496	408	SMARCAL1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 [Source:HGNC Symbol;Acc:HGNC:11102]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0035861//site of double-strand break;GO:0043596//nuclear replication fork	"GO:0000166//nucleotide binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0140658//ATP-dependent chromatin remodeler activity"	GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0048478//replication fork protection;GO:0090656//t-circle formation	Others
ENSG00000138376	2.103	1.792	2.267	1.921	1.846	1.823	205	152	172	100	154	134	BARD1	BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10683	GO:0000151//ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0031436//BRCA1-BARD1 complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0070531//BRCA1-A complex;GO:0070532//BRCA1-B complex;GO:0070533//BRCA1-C complex	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0000209//protein polyubiquitination;GO:0001894//tissue homeostasis;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0031441//negative regulation of mRNA 3'-end processing;GO:0035518//histone H2A monoubiquitination;GO:0035825//homologous recombination;GO:0042325//regulation of phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0044818//mitotic G2/M transition checkpoint;GO:0045732//positive regulation of protein catabolic process;GO:0045786//negative regulation of cell cycle;GO:0046826//negative regulation of protein export from nucleus;GO:0051726//regulation of cell cycle;GO:0051865//protein autoubiquitination;GO:0070537//histone H2A K63-linked deubiquitination;GO:0071479//cellular response to ionizing radiation;GO:0085020//protein K6-linked ubiquitination;GO:0110025//DNA strand resection involved in replication fork processing;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000138378	0.075	0.019	0.276	0.127	0.045	0.104	4	1	3	5	2	4	STAT4	signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Cell growth and death;Infectious disease: viral;Immune system;Immune disease	ko05200//Pathways in cancer;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K11222;K11222;K11222;K11222;K11222;K11222	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0019221//cytokine-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0045944//positive regulation of transcription by RNA polymerase II"	STAT
ENSG00000138379	0.017	0	0	0	0	0	1	0	0	0	0	0	MSTN	myostatin [Source:HGNC Symbol;Acc:HGNC:4223]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05497	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	"GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007517//muscle organ development;GO:0009408//response to heat;GO:0009629//response to gravity;GO:0010592//positive regulation of lamellipodium assembly;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014732//skeletal muscle atrophy;GO:0014741//negative regulation of muscle hypertrophy;GO:0014839//myoblast migration involved in skeletal muscle regeneration;GO:0014850//response to muscle activity;GO:0022602//ovulation cycle process;GO:0033574//response to testosterone;GO:0033673//negative regulation of kinase activity;GO:0043403//skeletal muscle tissue regeneration;GO:0043627//response to estrogen;GO:0045471//response to ethanol;GO:0045662//negative regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046716//muscle cell cellular homeostasis;GO:0048632//negative regulation of skeletal muscle tissue growth;GO:0051384//response to glucocorticoid;GO:0051602//response to electrical stimulus;GO:0051898//negative regulation of protein kinase B signaling;GO:0060395//SMAD protein signal transduction;GO:0071549//cellular response to dexamethasone stimulus;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation;GO:1902725//negative regulation of satellite cell differentiation;GO:2000818//negative regulation of myoblast proliferation"	--
ENSG00000138380	3.701	3.666	3.457	2.569	2.71	3.337	274	195	146	115	165	176	CARF	calcium responsive transcription factor [Source:HGNC Symbol;Acc:HGNC:14435]	-	-	-	-	GO:0001652//granular component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0035865//cellular response to potassium ion;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0061400//positive regulation of transcription from RNA polymerase II promoter in response to calcium ion;GO:0071277//cellular response to calcium ion	Others
ENSG00000138381	17.622	15.729	15.563	14.438	15.574	17.234	777.7	711.77	486.34	423.4	568.33	525.91	ASNSD1	asparagine synthetase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24910]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity	GO:0006529//asparagine biosynthetic process;GO:0006541//glutamine metabolic process;GO:0008150//biological_process;GO:0008652//cellular amino acid biosynthetic process	--
ENSG00000138382	10.65	11.504	10.759	9.142	8.11	9.341	196.01	206	142	116	117	118	METTL5	"methyltransferase 5, N6-adenosine [Source:HGNC Symbol;Acc:HGNC:25006]"	-	-	-	-	GO:0005634//nucleus;GO:0030054//cell junction;GO:0042995//cell projection;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008988//rRNA (adenine-N6-)-methyltransferase activity;GO:0016740//transferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0045727//positive regulation of translation;GO:0048863//stem cell differentiation	--
ENSG00000138385	25.363	27.077	22.573	18.934	23.674	28.378	868.99	933	573	480	685	707	SSB	small RNA binding exonuclease protection factor La [Source:HGNC Symbol;Acc:HGNC:11316]	Human Diseases	Immune disease	ko05322//Systemic lupus erythematosus	K11090	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex"	GO:0000049//tRNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:1990825//sequence-specific mRNA binding	GO:0001682//tRNA 5'-leader removal;GO:0006396//RNA processing;GO:0006400//tRNA modification;GO:0006409//tRNA export from nucleus;GO:0008033//tRNA processing;GO:0008334//histone mRNA metabolic process;GO:0042780//tRNA 3'-end processing;GO:0071045//nuclear histone mRNA catabolic process;GO:0075522//IRES-dependent viral translational initiation;GO:1903608//protein localization to cytoplasmic stress granule	--
ENSG00000138386	11.303	7.595	8.597	8.068	6.909	4.762	594	447	360	279	363	287	NAB1	NGFI-A binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7626]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003712//transcription coregulator activity	"GO:0001958//endochondral ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0014037//Schwann cell differentiation;GO:0042552//myelination;GO:0045682//regulation of epidermis development;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000138395	0.987	0.891	0.579	2.226	2.254	1.71	72	58	33	125	136	96	CDK15	cyclin dependent kinase 15 [Source:HGNC Symbol;Acc:HGNC:14434]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000138398	3.93	3.332	2.89	1.701	1.993	2.903	349	280	198	113	148	161	PPIG	peptidylprolyl isomerase G [Source:HGNC Symbol;Acc:HGNC:14650]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0008380//RNA splicing	--
ENSG00000138399	5.123	5.361	6.207	4.47	4.418	5.928	324	330	286	197	221	272	FASTKD1	FAST kinase domains 1 [Source:HGNC Symbol;Acc:HGNC:26150]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000959//mitochondrial RNA metabolic process;GO:0000963//mitochondrial RNA processing;GO:0044528//regulation of mitochondrial mRNA stability	--
ENSG00000138400	2.705	2.118	3.036	1.484	1.694	1.345	114	94	93	46	63	39	MDH1B	malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]	-	-	-	-	-	"GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity;GO:0016615//malate dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030060//L-malate dehydrogenase activity"	GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006108//malate metabolic process;GO:0006734//NADH metabolic process	--
ENSG00000138411	0.114	0.145	0.075	0.059	0.195	0.049	22	24	7	10	18	7	HECW2	"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:29853]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0072686//mitotic spindle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0048814//regulation of dendrite morphogenesis;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000138413	99.693	94.083	106.613	105.37	104.024	118.461	4766	4461	3745	3698	4180	4074	IDH1	isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382]	Metabolism;Metabolism;Cellular Processes;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Transport and catabolism;Global and overview maps;Cancer: overview;Metabolism of other amino acids;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04146//Peroxisome;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00480//Glutathione metabolism;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K00031;K00031;K00031;K00031;K00031;K00031;K00031;K00031	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	"GO:0000287//magnesium ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0050661//NADP binding;GO:0051287//NAD binding"	GO:0006097//glyoxylate cycle;GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006739//NADP metabolic process;GO:0006749//glutathione metabolic process;GO:0006979//response to oxidative stress;GO:0008585//female gonad development;GO:0014070//response to organic cyclic compound;GO:0048545//response to steroid hormone;GO:0060696//regulation of phospholipid catabolic process;GO:0071071//regulation of phospholipid biosynthetic process	--
ENSG00000138430	35.739	30.898	29.303	29.107	30.32	31.251	1276	1139	796	778	921	815	OLA1	Obg like ATPase 1 [Source:HGNC Symbol;Acc:HGNC:28833]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043022//ribosome binding;GO:0043023//ribosomal large subunit binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0046034//ATP metabolic process	--
ENSG00000138433	5.8	5.174	3.437	3.461	2.885	4.111	226	202	101	102	92	119	CIR1	"corepressor interacting with RBPJ, CIR1 [Source:HGNC Symbol;Acc:HGNC:24217]"	Human Diseases;Environmental Information Processing	Infectious disease: viral;Signal transduction	ko05169//Epstein-Barr virus infection;ko04330//Notch signaling pathway	K06066;K06066	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042826//histone deacetylase binding;GO:0044877//protein-containing complex binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000138434	87.728	76.791	75.816	52.729	58.749	72.268	9289	7965	5711	3958	5053	5308	ITPRID2	ITPR interacting domain containing 2 [Source:HGNC Symbol;Acc:HGNC:11319]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0051015//actin filament binding	-	--
ENSG00000138435	0	0.066	0	0	0.029	0.136	0	2	0	0	1	3	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04803	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0003009//skeletal muscle contraction;GO:0006811//ion transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007274//neuromuscular synaptic transmission;GO:0007528//neuromuscular junction development;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0046716//muscle cell cellular homeostasis;GO:0048630//skeletal muscle tissue growth;GO:0050877//nervous system process;GO:0050881//musculoskeletal movement;GO:0050905//neuromuscular process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0070050//neuron cellular homeostasis"	--
ENSG00000138439	1.62	1.379	1.299	1.11	1.297	1.019	201	172	119	102	136	92	FAM117B	family with sequence similarity 117 member B [Source:HGNC Symbol;Acc:HGNC:14440]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000138442	2.791	2.531	2.567	2.703	2.681	2.998	499	455	339	358	405	390	WDR12	WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0070545//PeBoW complex"	GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0007219//Notch signaling pathway;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0051726//regulation of cell cycle"	--
ENSG00000138443	44.038	38.969	41.778	31.056	35.728	36.973	3754.83	3370.03	2462.15	2123.57	2530.27	2432.66	ABI2	abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05751	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0031209//SCAR complex;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0017124//SH3 domain binding;GO:0019900//kinase binding;GO:0031267//small GTPase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035591//signaling adaptor activity;GO:0042802//identical protein binding;GO:0070064//proline-rich region binding	GO:0007010//cytoskeleton organization;GO:0007399//nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0010592//positive regulation of lamellipodium assembly;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0061001//regulation of dendritic spine morphogenesis;GO:0070309//lens fiber cell morphogenesis;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000138448	279.004	226.108	212.13	129.171	169.199	161.062	39527	31922	22858	13878	19219	17110	ITGAV	integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cell motility;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease;Endocrine system;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04919//Thyroid hormone signaling pathway;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487;K06487	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031258//lamellipodium membrane;GO:0031527//filopodium membrane;GO:0031528//microvillus membrane;GO:0032587//ruffle membrane;GO:0034683//integrin alphav-beta3 complex;GO:0034684//integrin alphav-beta5 complex;GO:0034685//integrin alphav-beta6 complex;GO:0034686//integrin alphav-beta8 complex;GO:0035579//specific granule membrane;GO:0035866//alphav-beta3 integrin-PKCalpha complex;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0035868//alphav-beta3 integrin-HMGB1 complex;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0001846//opsonin binding;GO:0001968//fibronectin binding;GO:0002020//protease binding;GO:0005080//protein kinase C binding;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0017134//fibroblast growth factor binding;GO:0019960//C-X3-C chemokine binding;GO:0031994//insulin-like growth factor I binding;GO:0038132//neuregulin binding;GO:0046872//metal ion binding;GO:0050431//transforming growth factor beta binding;GO:0050840//extracellular matrix binding;GO:1990430//extracellular matrix protein binding	GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0031589//cell-substrate adhesion;GO:0032369//negative regulation of lipid transport;GO:0033627//cell adhesion mediated by integrin;GO:0033690//positive regulation of osteoblast proliferation;GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035987//endodermal cell differentiation;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0043277//apoptotic cell clearance;GO:0045785//positive regulation of cell adhesion;GO:0046718//viral entry into host cell;GO:0050748//negative regulation of lipoprotein metabolic process;GO:0050764//regulation of phagocytosis;GO:0050919//negative chemotaxis;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0070371//ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport;GO:0071604//transforming growth factor beta production;GO:0085017//entry into host cell by a symbiont-containing vacuole;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0098609//cell-cell adhesion;GO:1901388//regulation of transforming growth factor beta activation;GO:1902533//positive regulation of intracellular signal transduction;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:2000536//negative regulation of entry of bacterium into host cell;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000138449	18.039	18.293	18.995	20.601	19.724	19.46	1246	1270	969	1054	1151	978	SLC40A1	solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909]	Organismal Systems;Cellular Processes	Digestive system;Cell growth and death	ko04978//Mineral absorption;ko04216//Ferroptosis	K14685;K14685	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005381//iron ion transmembrane transporter activity;GO:0005515//protein binding;GO:0015093//ferrous iron transmembrane transporter activity;GO:0017046//peptide hormone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002260//lymphocyte homeostasis;GO:0003158//endothelium development;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0034395//regulation of transcription from RNA polymerase II promoter in response to iron;GO:0034755//iron ion transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048536//spleen development;GO:0055072//iron ion homeostasis;GO:0060345//spleen trabecula formation;GO:0060586//multicellular organismal iron ion homeostasis;GO:1903988//iron ion export across plasma membrane	--
ENSG00000138459	13.025	14.302	14.117	13.526	10.874	15.191	1027	1036	820	768	751	788	SLC35A5	solute carrier family 35 member A5 [Source:HGNC Symbol;Acc:HGNC:20792]	-	-	-	-	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport	--
ENSG00000138463	9.369	7.76	9.875	8.451	8.977	10.697	493	445	367	311	377	410	SLC49A4	solute carrier family 49 member 4 [Source:HGNC Symbol;Acc:HGNC:16628]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000138468	4.04	3.696	3.369	2.044	3.707	3.263	341	254	189	140	229	154	SENP7	SUMO specific peptidase 7 [Source:HGNC Symbol;Acc:HGNC:30402]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070139//SUMO-specific endopeptidase activity	GO:0006508//proteolysis;GO:0016926//protein desumoylation;GO:0140374//antiviral innate immune response	--
ENSG00000138472	0	0	0	0	0	0	0	0	0	0	0	0	GUCA1C	guanylate cyclase activator 1C [Source:HGNC Symbol;Acc:HGNC:4680]	Organismal Systems	Sensory system	ko04744//Phototransduction	K08328	GO:0097381//photoreceptor disc membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0031282//regulation of guanylate cyclase activity;GO:0031284//positive regulation of guanylate cyclase activity	--
ENSG00000138483	0	0	0.164	0	0	0	0	0	3	0	0	0	CCDC54	coiled-coil domain containing 54 [Source:HGNC Symbol;Acc:HGNC:30703]	-	-	-	-	-	-	-	--
ENSG00000138495	30.415	19.884	32.887	32.104	22.666	32.961	272	179	217	213	173	215	COX17	cytochrome c oxidase copper chaperone COX17 [Source:HGNC Symbol;Acc:HGNC:2264]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02260;K02260;K02260	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016531//copper chaperone activity;GO:0046872//metal ion binding;GO:1903136//cuprous ion binding	GO:0006091//generation of precursor metabolites and energy;GO:0006825//copper ion transport;GO:0008284//positive regulation of cell population proliferation;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:1904960//positive regulation of cytochrome-c oxidase activity	--
ENSG00000138496	8.469	8.891	9.331	7.983	7.592	8.275	581	607	459	404	445	420	PARP9	poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0090734//site of DNA damage	GO:0003714//transcription corepressor activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0072570//ADP-D-ribose binding;GO:0097677//STAT family protein binding;GO:1990404//protein ADP-ribosylase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006471//protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus;GO:0010608//posttranscriptional regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016477//cell migration;GO:0019082//viral protein processing;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0035563//positive regulation of chromatin binding;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051607//defense response to virus;GO:0060330//regulation of response to interferon-gamma;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0140289//protein mono-ADP-ribosylation;GO:1900182//positive regulation of protein localization to nucleus;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000138587	0.736	0.409	0.376	0.142	0.337	0.137	31	17.29	11.7	4.44	12	4.21	MNS1	meiosis specific nuclear structural 1 [Source:HGNC Symbol;Acc:HGNC:29636]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0044782//cilium organization;GO:0045724//positive regulation of cilium assembly;GO:0051321//meiotic cell cycle;GO:0070986//left/right axis specification	--
ENSG00000138592	9.32	9.912	6.978	5.059	6.26	6.421	600	558	382	202	298	259	USP8	ubiquitin specific peptidase 8 [Source:HGNC Symbol;Acc:HGNC:12631]	Cellular Processes;Human Diseases;Cellular Processes	Transport and catabolism;Endocrine and metabolic disease;Transport and catabolism	ko04144//Endocytosis;ko04934//Cushing syndrome;ko04137//Mitophagy - animal	K11839;K11839;K11839	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030496//midbody;GO:0031313//extrinsic component of endosome membrane;GO:0043197//dendritic spine;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0045296//cadherin binding	"GO:0000281//mitotic cytokinesis;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007032//endosome organization;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability;GO:0032880//regulation of protein localization;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071549//cellular response to dexamethasone stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0099576//regulation of protein catabolic process at postsynapse, modulating synaptic transmission;GO:1990090//cellular response to nerve growth factor stimulus"	--
ENSG00000138593	14.039	9.819	10.648	8.52	8.929	9.798	2031	1431	1061	915	1086	1015	SECISBP2L	SECIS binding protein 2 like [Source:HGNC Symbol;Acc:HGNC:28997]	-	-	-	-	GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035368//selenocysteine insertion sequence binding;GO:0043021//ribonucleoprotein complex binding	GO:0001514//selenocysteine incorporation	--
ENSG00000138594	5.225	3.874	3.768	3.5	3.812	5.068	870	629	437	416	471	481	TMOD3	tropomodulin 3 [Source:HGNC Symbol;Acc:HGNC:11873]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0005912//adherens junction;GO:0030016//myofibril	GO:0003779//actin binding;GO:0005523//tropomyosin binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0030239//myofibril assembly;GO:0048821//erythrocyte development;GO:0051694//pointed-end actin filament capping;GO:0098609//cell-cell adhesion;GO:1901992//positive regulation of mitotic cell cycle phase transition	--
ENSG00000138600	41.428	39.397	49.625	36.404	36.239	46.513	1808.19	1744	1510	1309	1472	1568	SPPL2A	signal peptide peptidase like 2A [Source:HGNC Symbol;Acc:HGNC:30227]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0042803//protein homodimerization activity"	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0031293//membrane protein intracellular domain proteolysis;GO:0033619//membrane protein proteolysis;GO:0050776//regulation of immune response	--
ENSG00000138604	5.977	5.361	5.239	4.387	4.435	5.72	615	554	395	340	392	430	GLCE	glucuronic acid epimerase [Source:HGNC Symbol;Acc:HGNC:17855]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K01793;K01793	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005509//calcium ion binding;GO:0016853//isomerase activity;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047464//heparosan-N-sulfate-glucuronate 5-epimerase activity"	GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030210//heparin biosynthetic process	--
ENSG00000138606	3.183	3.063	3.867	2.269	3.565	3.286	92	104	68	64	82	82	SHF	Src homology 2 domain containing F [Source:HGNC Symbol;Acc:HGNC:25116]	-	-	-	-	-	GO:0001784//phosphotyrosine residue binding	GO:0006915//apoptotic process	--
ENSG00000138613	5.206	2.612	3.108	4.795	4.295	5.313	252	217	197	210	268	291	APH1B	"aph-1 homolog B, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:24080]"	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05010//Alzheimer disease;ko04330//Notch signaling pathway	K06172;K06172	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0070765//gamma-secretase complex	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0061133//endopeptidase activator activity	GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0010950//positive regulation of endopeptidase activity;GO:0016485//protein processing;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034205//amyloid-beta formation;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity	--
ENSG00000138614	14.496	13.919	13.273	12.492	17.167	13.245	565	601	423	411	519	400	INTS14	integrator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:25372]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0034472//snRNA 3'-end processing	--
ENSG00000138615	0.042	0.093	0.034	0.069	0.121	0.047	5	11	3	6	12	4	CILP	cartilage intermediate layer protein [Source:HGNC Symbol;Acc:HGNC:1980]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent	GO:0010629//negative regulation of gene expression;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000138617	3.63	3.18	4.221	4.917	4.706	4.075	200	176	176	181	214	163	PARP16	poly(ADP-ribose) polymerase family member 16 [Source:HGNC Symbol;Acc:HGNC:26040]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019900//kinase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:1990404//protein ADP-ribosylase activity	GO:0006471//protein ADP-ribosylation;GO:0006986//response to unfolded protein;GO:0019082//viral protein processing;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:0060548//negative regulation of cell death;GO:0070213//protein auto-ADP-ribosylation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0140289//protein mono-ADP-ribosylation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000138621	4.11	3.534	2.86	3.726	2.96	3.894	58	61	42	50	52	46	PPCDC	phosphopantothenoylcysteine decarboxylase [Source:HGNC Symbol;Acc:HGNC:28107]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K01598;K01598	GO:0005829//cytosol;GO:0071513//phosphopantothenoylcysteine decarboxylase complex	GO:0003824//catalytic activity;GO:0004633//phosphopantothenoylcysteine decarboxylase activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0042802//identical protein binding	GO:0015937//coenzyme A biosynthetic process	--
ENSG00000138622	0.063	0.042	0.085	0.122	0.025	0.019	9	6	9	13	3	2	HCN4	hyperpolarization activated cyclic nucleotide gated potassium channel 4 [Source:HGNC Symbol;Acc:HGNC:16882]	Environmental Information Processing;Organismal Systems	Signal transduction;Sensory system	ko04024//cAMP signaling pathway;ko04742//Taste transduction	K04957;K04957	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0098855//HCN channel complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005272//sodium channel activity;GO:0030552//cAMP binding;GO:0042802//identical protein binding;GO:0086041//voltage-gated potassium channel activity involved in SA node cell action potential depolarization	GO:0002027//regulation of heart rate;GO:0003163//sinoatrial node development;GO:0003254//regulation of membrane depolarization;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006936//muscle contraction;GO:0008015//blood circulation;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0055117//regulation of cardiac muscle contraction;GO:0071320//cellular response to cAMP;GO:0071321//cellular response to cGMP;GO:0071805//potassium ion transmembrane transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086015//SA node cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098719//sodium ion import across plasma membrane;GO:0098907//regulation of SA node cell action potential;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:1990573//potassium ion import across plasma membrane;GO:2001257//regulation of cation channel activity	--
ENSG00000138623	1.101	1.007	0.627	1.195	1.708	1.421	76	57	27	62	86	66	SEMA7A	semaphorin 7A (John Milton Hagen blood group) [Source:HGNC Symbol;Acc:HGNC:10741]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06529	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001649//osteoblast differentiation;GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007229//integrin-mediated signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0021988//olfactory lobe development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0045773//positive regulation of axon extension;GO:0048675//axon extension;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050727//regulation of inflammatory response;GO:0050919//negative chemotaxis;GO:0060907//positive regulation of macrophage cytokine production;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000138629	24.635	27.867	29.392	31.4	30.623	27.446	696	790	617	647	718	566	UBL7	ubiquitin like 7 [Source:HGNC Symbol;Acc:HGNC:28221]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0006511//ubiquitin-dependent protein catabolic process	--
ENSG00000138639	2.753	2.989	3.018	2.864	2.786	2.937	167.64	156	118	112	128	127	ARHGAP24	Rho GTPase activating protein 24 [Source:HGNC Symbol;Acc:HGNC:25361]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0042995//cell projection	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0035021//negative regulation of Rac protein signal transduction;GO:0035313//wound healing, spreading of epidermal cells;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity;GO:1900028//negative regulation of ruffle assembly"	--
ENSG00000138640	88.351	77.214	76.65	57.133	61.202	65.934	7254	6518	4684	3456	4255	3942	FAM13A	family with sequence similarity 13 member A [Source:HGNC Symbol;Acc:HGNC:19367]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000138641	7.363	5.095	6.129	6.074	6.782	7.378	569.32	515.55	439.49	396.79	444.19	453.51	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:4876]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10614	GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity	GO:0016567//protein ubiquitination	--
ENSG00000138642	0.74	0.991	0.743	1.558	0.574	0.456	58	78	43	38	38	26	HERC6	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0009617//response to bacterium;GO:0016567//protein ubiquitination	--
ENSG00000138646	0.993	0.956	0.985	0.593	0.591	0.793	65	70	53	32	33	42	HERC5	HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0042296//ISG15 transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0002376//immune system process;GO:0016567//protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0045087//innate immune response;GO:0050688//regulation of defense response to virus;GO:0051607//defense response to virus	--
ENSG00000138650	3.072	3.152	2.253	0.685	1.136	0.825	417	438	237	73	125	88	PCDH10	protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000138653	0.031	0.046	0.063	0.032	0	0.132	2	3	3	1	0	4	NDST4	N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02579;K02579	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0008146//sulfotransferase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity	"GO:0008152//metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030210//heparin biosynthetic process"	--
ENSG00000138658	0.753	0.276	0.48	0.313	0.176	0.474	52	19	34	22	16	21	ZGRF1	zinc finger GRF-type containing 1 [Source:HGNC Symbol;Acc:HGNC:25654]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0008270//zinc ion binding;GO:0017108//5'-flap endonuclease activity;GO:0046872//metal ion binding	GO:0071932//replication fork reversal	--
ENSG00000138660	4.173	3.193	3.74	4.386	3.146	4.932	285	202	194	212	184	221	AP1AR	adaptor related protein complex 1 associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28808]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030133//transport vesicle	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0035650//AP-1 adaptor complex binding	"GO:0001920//negative regulation of receptor recycling;GO:0015031//protein transport;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0034613//cellular protein localization;GO:0048203//vesicle targeting, trans-Golgi to endosome;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:2000146//negative regulation of cell motility"	--
ENSG00000138663	19.344	20.252	19.818	18.049	16.666	17.158	655	707	503	467	491	434	COPS4	COP9 signalosome subunit 4 [Source:HGNC Symbol;Acc:HGNC:16702]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0008180//COP9 signalosome;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0045202//synapse	GO:0005515//protein binding;GO:0019784//NEDD8-specific protease activity	GO:0000338//protein deneddylation;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000138668	82.428	86.115	89.082	96.422	89.323	93.378	2132	2172	1630	1776	1853	1766	HNRNPD	heterogeneous nuclear ribonucleoprotein D [Source:HGNC Symbol;Acc:HGNC:5036]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045202//synapse;GO:0106002//mCRD-mediated mRNA stability complex;GO:0110165//cellular anatomical entity;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0042162//telomeric DNA binding;GO:0042826//histone deacetylase binding	"GO:0001889//liver development;GO:0006355//regulation of transcription, DNA-templated;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0007420//brain development;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0021549//cerebellum development;GO:0032204//regulation of telomere maintenance;GO:0032355//response to estradiol;GO:0042752//regulation of circadian rhythm;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048255//mRNA stabilization;GO:0048511//rhythmic process;GO:0051592//response to calcium ion;GO:0051602//response to electrical stimulus;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0070934//CRD-mediated mRNA stabilization;GO:0071230//cellular response to amino acid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071732//cellular response to nitric oxide;GO:0097167//circadian regulation of translation;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901355//response to rapamycin;GO:1904355//positive regulation of telomere capping;GO:1904383//response to sodium phosphate;GO:1904586//cellular response to putrescine;GO:1905663//positive regulation of telomerase RNA reverse transcriptase activity;GO:1990828//hepatocyte dedifferentiation;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000138669	0.171	0.112	0	0.068	0.033	0.039	12	9	0	4	2	2	PRKG2	protein kinase cGMP-dependent 2 [Source:HGNC Symbol;Acc:HGNC:9416]	Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems	Sensory system;Environmental adaptation;Signal transduction;Immune system;Environmental adaptation;Digestive system;Cellular community - eukaryotes;Endocrine system;Endocrine system;Nervous system	ko04740//Olfactory transduction;ko04714//Thermogenesis;ko04022//cGMP-PKG signaling pathway;ko04611//Platelet activation;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04540//Gap junction;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression	K19477;K19477;K19477;K19477;K19477;K19477;K19477;K19477;K19477;K19477	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031965//nuclear membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004692//cGMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030553//cGMP binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0032330//regulation of chondrocyte differentiation;GO:0036289//peptidyl-serine autophosphorylation;GO:0046146//tetrahydrobiopterin metabolic process;GO:0072659//protein localization to plasma membrane;GO:1902731//negative regulation of chondrocyte proliferation;GO:2001226//negative regulation of chloride transport	--
ENSG00000138670	8.074	9.038	6.488	5.047	5.748	4.737	439	473	266	188	224	196	RASGEF1B	RasGEF domain family member 1B [Source:HGNC Symbol;Acc:HGNC:24881]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0030496//midbody	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000138674	77.068	79.66	67.436	60.67	69.285	62.322	4665	4822	3113	2686	3340	2713	SEC31A	"SEC31 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:17052]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14005	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030120//vesicle coat;GO:0030127//COPII vesicle coat;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070971//endoplasmic reticulum exit site	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0051592//response to calcium ion;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000138675	0.94	0.697	0.406	0.554	1.013	0.804	103	77	33.02	45	94	64.04	FGF5	fibroblast growth factor 5 [Source:HGNC Symbol;Acc:HGNC:3683]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010001//glial cell differentiation;GO:0010628//positive regulation of gene expression;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0051781//positive regulation of cell division	--
ENSG00000138678	1.099	1.117	0.895	1.075	1.225	1.259	60	63	38	44	60	50	GPAT3	glycerol-3-phosphate acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:28157]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13506;K13506;K13506	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0102420//sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	GO:0006072//glycerol-3-phosphate metabolic process;GO:0006629//lipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0032006//regulation of TOR signaling	--
ENSG00000138684	0	0.166	0	0	0	0	0	2	0	0	0	0	IL21	interleukin 21 [Source:HGNC Symbol;Acc:HGNC:6005]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Signal transduction;Immune system;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease	K05434;K05434;K05434;K05434	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding	GO:0001819//positive regulation of cytokine production;GO:0002314//germinal center B cell differentiation;GO:0002639//positive regulation of immunoglobulin production;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0008284//positive regulation of cell population proliferation;GO:0030890//positive regulation of B cell proliferation;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0034105//positive regulation of tissue remodeling;GO:0042102//positive regulation of T cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048469//cell maturation;GO:0048856//anatomical structure development;GO:0050729//positive regulation of inflammatory response;GO:0050896//response to stimulus;GO:0051607//defense response to virus;GO:0060255//regulation of macromolecule metabolic process;GO:0061470//T follicular helper cell differentiation;GO:0098586//cellular response to virus	--
ENSG00000138685	21.459	15.328	15.774	13.406	13.711	16.435	2949.77	2154.3	1621.67	1374.87	1602.05	1647.15	FGF2	fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05218//Melanoma	K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497;K18497	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0019956//chemokine binding;GO:0030374//nuclear receptor coactivator activity;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0090722//receptor-receptor interaction	"GO:0001525//angiogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001759//organ induction;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009792//embryo development ending in birth or egg hatching;GO:0009887//animal organ morphogenesis;GO:0010001//glial cell differentiation;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010764//negative regulation of fibroblast migration;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014843//growth factor dependent regulation of skeletal muscle satellite cell proliferation;GO:0021762//substantia nigra development;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0030154//cell differentiation;GO:0030214//hyaluronan catabolic process;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0032958//inositol phosphate biosynthetic process;GO:0038001//paracrine signaling;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0042660//positive regulation of cell fate specification;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045597//positive regulation of cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045765//regulation of angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046668//regulation of retinal cell programmed cell death;GO:0048513//animal organ development;GO:0048598//embryonic morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048678//response to axon injury;GO:0048864//stem cell development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050918//positive chemotaxis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051726//regulation of cell cycle;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0060548//negative regulation of cell death;GO:0060591//chondroblast differentiation;GO:0060644//mammary gland epithelial cell differentiation;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0061045//negative regulation of wound healing;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072089//stem cell proliferation;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902748//positive regulation of lens fiber cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903587//regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905278//positive regulation of epithelial tube formation;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000544//regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:2000573//positive regulation of DNA biosynthetic process;GO:2001028//positive regulation of endothelial cell chemotaxis"	--
ENSG00000138686	4.876	3.716	4.186	3.326	3.792	3.976	306	256	195	160	207	180	BBS7	Bardet-Biedl syndrome 7 [Source:HGNC Symbol;Acc:HGNC:18758]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0034464//BBSome;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0060170//ciliary membrane	GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001654//eye development;GO:0001947//heart looping;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0007507//heart development;GO:0007601//visual perception;GO:0008104//protein localization;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0032402//melanosome transport;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045444//fat cell differentiation;GO:0046907//intracellular transport;GO:0048546//digestive tract morphogenesis;GO:0050896//response to stimulus;GO:0051877//pigment granule aggregation in cell center;GO:0060173//limb development;GO:0060271//cilium assembly;GO:1903929//primary palate development;GO:1905515//non-motile cilium assembly	--
ENSG00000138688	19.805	10.041	11.074	8.3	10.433	13.813	3448	1823	1546	1056	1631	1831	KIAA1109	KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098793//presynapse	GO:0005515//protein binding	GO:0001558//regulation of cell growth;GO:0006909//phagocytosis;GO:0016197//endosomal transport;GO:0030856//regulation of epithelial cell differentiation;GO:0032456//endocytic recycling;GO:0048488//synaptic vesicle endocytosis	--
ENSG00000138696	8.223	8.92	6.388	2.405	3.085	2.975	553	573	299	121	179	152	BMPR1B	bone morphogenetic protein receptor type 1B [Source:HGNC Symbol;Acc:HGNC:1077]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Development and regeneration;Signal transduction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04360//Axon guidance;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K13578;K13578;K13578;K13578;K13578;K13578	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:1990712//HFE-transferrin receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019211//phosphatase activator activity;GO:0036122//BMP binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0098821//BMP receptor activity"	GO:0001502//cartilage condensation;GO:0001550//ovarian cumulus expansion;GO:0001649//osteoblast differentiation;GO:0001654//eye development;GO:0002062//chondrocyte differentiation;GO:0002063//chondrocyte development;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0030166//proteoglycan biosynthetic process;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0031290//retinal ganglion cell axon guidance;GO:0032332//positive regulation of chondrocyte differentiation;GO:0042698//ovulation cycle;GO:0043010//camera-type eye development;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051216//cartilage development;GO:0060041//retina development in camera-type eye;GO:0060348//bone development;GO:0060350//endochondral bone morphogenesis;GO:0061036//positive regulation of cartilage development;GO:0071363//cellular response to growth factor stimulus;GO:0071773//cellular response to BMP stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902731//negative regulation of chondrocyte proliferation	--
ENSG00000138698	9.306	7.984	8.179	6.445	8.002	9.048	574	499	354	302	397	405	RAP1GDS1	Rap1 GTPase-GDP dissociation stimulator 1 [Source:HGNC Symbol;Acc:HGNC:9859]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0014829//vascular associated smooth muscle contraction;GO:0031034//myosin filament assembly;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0043547//positive regulation of GTPase activity;GO:0051561//positive regulation of mitochondrial calcium ion concentration	--
ENSG00000138709	3.682	3.286	2.973	3.724	3.502	3.415	221	189	136	136	184	147	LARP1B	La ribonucleoprotein 1B [Source:HGNC Symbol;Acc:HGNC:24704]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0045727//positive regulation of translation	--
ENSG00000138722	0.039	0.133	0.146	0.104	0.071	0.119	4	9	10	8	4	9	MMRN1	multimerin 1 [Source:HGNC Symbol;Acc:HGNC:7178]	-	-	-	-	GO:0005576//extracellular region;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity;GO:1990972//multimerin complex	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0033627//cell adhesion mediated by integrin;GO:0061045//negative regulation of wound healing;GO:1901731//positive regulation of platelet aggregation	--
ENSG00000138735	4.05	3.796	2.508	3.751	2.863	3.445	546	443	250	251	287	216	PDE5A	phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Nucleotide metabolism	ko01100//Metabolic pathways;ko04022//cGMP-PKG signaling pathway;ko00230//Purine metabolism	K13762;K13762;K13762	GO:0005575//cellular_component;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030553//cGMP binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010749//regulation of nitric oxide mediated signal transduction;GO:0042130//negative regulation of T cell proliferation;GO:0043406//positive regulation of MAP kinase activity;GO:0046068//cGMP metabolic process;GO:0046069//cGMP catabolic process;GO:0055118//negative regulation of cardiac muscle contraction;GO:0055119//relaxation of cardiac muscle;GO:0060282//positive regulation of oocyte development	--
ENSG00000138738	1.856	2.488	1.283	1.854	1.868	2.307	115	151	61	93	97	111	PRDM5	PR/SET domain 5 [Source:HGNC Symbol;Acc:HGNC:9349]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0010468//regulation of gene expression;GO:0016575//histone deacetylation;GO:0032259//methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051567//histone H3-K9 methylation;GO:1903053//regulation of extracellular matrix organization;GO:1990830//cellular response to leukemia inhibitory factor"	zf-C2H2
ENSG00000138741	0.04	0.128	0.09	0.116	0.093	0.098	2	9	6	8	6	4	TRPC3	transient receptor potential cation channel subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:12335]	Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Development and regeneration;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko04360//Axon guidance;ko05017//Spinocerebellar ataxia	K04966;K04966;K04966	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034703//cation channel complex	"GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0007338//single fertilization;GO:0007602//phototransduction;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0033198//response to ATP;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:1903244//positive regulation of cardiac muscle hypertrophy in response to stress	--
ENSG00000138744	2.565	3.397	2.908	2.232	3.069	2.607	78	86	68	54	69	56	NAAA	N-acylethanolamine acid amidase [Source:HGNC Symbol;Acc:HGNC:736]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0017064//fatty acid amide hydrolase activity;GO:0047412//N-(long-chain-acyl)ethanolamine deacylase activity;GO:0102121//ceramidase activity;GO:0140297//DNA-binding transcription factor binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006670//sphingosine metabolic process;GO:0016042//lipid catabolic process;GO:0070291//N-acylethanolamine metabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process	--
ENSG00000138750	7.379	6.913	5.433	5.614	5.708	5.729	345	325	186	186	214	193	NUP54	nucleoporin 54 [Source:HGNC Symbol;Acc:HGNC:17359]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14308;K14308	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0044613//nuclear pore central transport channel	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006605//protein targeting;GO:0006607//NLS-bearing protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0015031//protein transport;GO:0036228//protein localization to nuclear inner membrane;GO:0042306//regulation of protein import into nucleus;GO:0051028//mRNA transport	--
ENSG00000138755	0	0	0	0	0.062	0	0	0	0	0	3	0	CXCL9	C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05416;K05416;K05416;K05416	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0045236//CXCR chemokine receptor binding;GO:0048248//CXCR3 chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009617//response to bacterium;GO:0030593//neutrophil chemotaxis;GO:0042127//regulation of cell population proliferation;GO:0045663//positive regulation of myoblast differentiation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051607//defense response to virus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:1901741//positive regulation of myoblast fusion	--
ENSG00000138756	3.001	2.316	2	1.274	1.92	1.7	399.1	290.3	208.11	123.82	231.87	157.84	BMP2K	BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K08854	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019208//phosphatase regulator activity;GO:0035612//AP-2 adaptor complex binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030500//regulation of bone mineralization;GO:0045747//positive regulation of Notch signaling pathway;GO:0050790//regulation of catalytic activity;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000138757	70.302	61.925	60.039	54.741	56.199	62.421	4972	4398	3132	2891	3331	3175	G3BP2	G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0043229//intracellular organelle;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity	GO:0002376//immune system process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0007265//Ras protein signal transduction;GO:0034063//stress granule assembly;GO:0045087//innate immune response;GO:0051028//mRNA transport;GO:0051260//protein homooligomerization;GO:0062029//positive regulation of stress granule assembly	--
ENSG00000138758	9.973	9.377	8.065	6.287	6.798	7.444	991	932	595	466	581	523	SEPTIN11	septin 11 [Source:HGNC Symbol;Acc:HGNC:25589]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16939;K16939	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0030424//axon;GO:0031105//septin complex;GO:0032153//cell division site;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000138759	3.708	4.541	3.4	4.194	5.117	4.133	1122	1363	694	933	1367	932	FRAS1	Fraser extracellular matrix complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:19185]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K23379	GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002009//morphogenesis of an epithelium;GO:0003338//metanephros morphogenesis;GO:0007154//cell communication;GO:0015031//protein transport;GO:0030326//embryonic limb morphogenesis;GO:0043588//skin development;GO:0060021//roof of mouth development	--
ENSG00000138760	86.579	80.212	73.2	67.272	70.942	74.292	8339	7495	5247	4678	5459	5035	SCARB2	scavenger receptor class B member 2 [Source:HGNC Symbol;Acc:HGNC:1665]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12384	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031902//late endosome membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0001786//phosphatidylserine binding;GO:0004888//transmembrane signaling receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0031210//phosphatidylcholine binding;GO:0038024//cargo receptor activity;GO:0042803//protein homodimerization activity;GO:0051087//chaperone binding	GO:0006622//protein targeting to lysosome;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007605//sensory perception of sound;GO:0010467//gene expression;GO:0010976//positive regulation of neuron projection development;GO:0015917//aminophospholipid transport;GO:0043471//regulation of cellular carbohydrate catabolic process;GO:0046718//viral entry into host cell;GO:1904978//regulation of endosome organization;GO:1905123//regulation of glucosylceramidase activity;GO:1905671//regulation of lysosome organization	--
ENSG00000138764	17.811	17.967	14.306	16.569	16.262	15.965	937	840	580	607	676	573	CCNG2	cyclin G2 [Source:HGNC Symbol;Acc:HGNC:1593]	Environmental Information Processing;Cellular Processes	Signal transduction;Cell growth and death	ko04068//FoxO signaling pathway;ko04115//p53 signaling pathway	K10146;K10146	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007049//cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000138767	5.649	4.685	4.605	3.532	3.676	3.396	527	505	332	301	352	264	CNOT6L	CCR4-NOT transcription complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:18042]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12603	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030014//CCR4-NOT complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0008284//positive regulation of cell population proliferation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0031047//gene silencing by RNA;GO:0061157//mRNA destabilization;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000138768	24.028	18.67	17.083	14.507	16.816	18.257	2055	1605	1079	919	1215	1136	USO1	USO1 vesicle transport factor [Source:HGNC Symbol;Acc:HGNC:30904]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032252//secretory granule localization;GO:0045056//transcytosis;GO:0048211//Golgi vesicle docking;GO:0048280//vesicle fusion with Golgi apparatus;GO:0061025//membrane fusion;GO:1900076//regulation of cellular response to insulin stimulus	--
ENSG00000138769	1.661	1.56	2.22	1.824	1.477	2.205	170	145	137	102	118	133	CDKL2	cyclin dependent kinase like 2 [Source:HGNC Symbol;Acc:HGNC:1782]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007548//sex differentiation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000138771	17.226	17.104	17.362	15.668	16.94	17.867	3141	3174	2454	2158	2633	2356	SHROOM3	shroom family member 3 [Source:HGNC Symbol;Acc:HGNC:30422]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0043296//apical junction complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0000902//cell morphogenesis;GO:0001843//neural tube closure;GO:0002064//epithelial cell development;GO:0007015//actin filament organization;GO:0007389//pattern specification process;GO:0008360//regulation of cell shape;GO:0043482//cellular pigment accumulation;GO:0045176//apical protein localization	--
ENSG00000138772	19.79	19.321	14.387	21.914	22.161	22.77	539	576	317	479	547	477	ANXA3	annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030670//phagocytic vesicle membrane;GO:0042581//specific granule;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0004859//phospholipase inhibitor activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019834//phospholipase A2 inhibitor activity;GO:0048306//calcium-dependent protein binding	GO:0006909//phagocytosis;GO:0010595//positive regulation of endothelial cell migration;GO:0021766//hippocampus development;GO:0031100//animal organ regeneration;GO:0042742//defense response to bacterium;GO:0043086//negative regulation of catalytic activity;GO:0043312//neutrophil degranulation;GO:0045766//positive regulation of angiogenesis;GO:0051054//positive regulation of DNA metabolic process;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051384//response to glucocorticoid;GO:0070848//response to growth factor	--
ENSG00000138777	26.148	25.506	23.156	28.027	22.957	27.412	713	707	474	528	541	544	PPA2	inorganic pyrophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:28883]	Metabolism	Energy metabolism	ko00190//Oxidative phosphorylation	K01507	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0004427//inorganic diphosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:0006796//phosphate-containing compound metabolic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0071344//diphosphate metabolic process	--
ENSG00000138778	0.034	0.044	0.015	0	0.02	0	6	8	2	0	3	0	CENPE	centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0051233//spindle midzone;GO:0072686//mitotic spindle;GO:1990023//mitotic spindle midzone"	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0043515//kinetochore binding	GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0007080//mitotic metaphase plate congression;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045860//positive regulation of protein kinase activity;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051382//kinetochore assembly;GO:0099606//microtubule plus-end directed mitotic chromosome migration;GO:0099607//lateral attachment of mitotic spindle microtubules to kinetochore	--
ENSG00000138780	4.39	4.517	5.093	3.053	4.041	4.145	350	329	259	201.87	267	227	GSTCD	glutathione S-transferase C-terminal domain containing [Source:HGNC Symbol;Acc:HGNC:25806]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000138785	6.07	5.469	6.768	6.414	6.464	6.042	203	175	175	140.13	181	158	INTS12	integrator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:25067]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032039//integrator complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing	--
ENSG00000138792	0.499	0.385	0.58	0.474	0.449	0.43	71	55	61	50	54	41	ENPEP	glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K11141	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0001525//angiogenesis;GO:0002003//angiotensin maturation;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008217//regulation of blood pressure;GO:0008283//cell population proliferation;GO:0016477//cell migration;GO:0032835//glomerulus development;GO:0043171//peptide catabolic process	--
ENSG00000138794	5.892	4.892	5.231	3.545	5.252	5.749	171	142	126	89	136	137	CASP6	caspase 6 [Source:HGNC Symbol;Acc:HGNC:1507]	Human Diseases;Cellular Processes	Cardiovascular disease;Cell growth and death	ko05417//Lipid and atherosclerosis;ko04210//Apoptosis	K04396;K04396	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0002218//activation of innate immune response;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0016540//protein autoprocessing;GO:0030855//epithelial cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0060545//positive regulation of necroptotic process;GO:0070269//pyroptosis;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0072734//cellular response to staurosporine;GO:0097194//execution phase of apoptosis;GO:0097284//hepatocyte apoptotic process	--
ENSG00000138795	0.4	0.271	0.392	0.206	0.17	0.388	13	20	13	11	10	10	LEF1	lymphoid enhancer binding factor 1 [Source:HGNC Symbol;Acc:HGNC:6551]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05132//Salmonella infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04936//Alcoholic liver disease;ko04916//Melanogenesis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492;K04492	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990907//beta-catenin-TCF complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008301//DNA binding, bending;GO:0030331//estrogen receptor binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0045295//gamma-catenin binding;GO:0070016//armadillo repeat domain binding;GO:0070742//C2H2 zinc finger domain binding;GO:0140416//transcription regulator inhibitor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001649//osteoblast differentiation;GO:0001756//somitogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001944//vasculature development;GO:0002040//sprouting angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016055//Wnt signaling pathway;GO:0021542//dentate gyrus development;GO:0021766//hippocampus development;GO:0021861//forebrain radial glial cell differentiation;GO:0021873//forebrain neuroblast division;GO:0021943//formation of radial glial scaffolds;GO:0022407//regulation of cell-cell adhesion;GO:0022408//negative regulation of cell-cell adhesion;GO:0022409//positive regulation of cell-cell adhesion;GO:0030111//regulation of Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030223//neutrophil differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030335//positive regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0030854//positive regulation of granulocyte differentiation;GO:0030879//mammary gland development;GO:0032696//negative regulation of interleukin-13 production;GO:0032713//negative regulation of interleukin-4 production;GO:0032714//negative regulation of interleukin-5 production;GO:0033153//T cell receptor V(D)J recombination;GO:0042100//B cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043586//tongue development;GO:0043923//positive regulation by host of viral transcription;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045063//T-helper 1 cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045843//negative regulation of striated muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046632//alpha-beta T cell differentiation;GO:0048341//paraxial mesoderm formation;GO:0048468//cell development;GO:0050767//regulation of neurogenesis;GO:0050909//sensory perception of taste;GO:0060033//anatomical structure regression;GO:0060070//canonical Wnt signaling pathway;GO:0060325//face morphogenesis;GO:0060326//cell chemotaxis;GO:0060561//apoptotic process involved in morphogenesis;GO:0060710//chorio-allantoic fusion;GO:0061153//trachea gland development;GO:0062009//secondary palate development;GO:0071345//cellular response to cytokine stimulus;GO:0071353//cellular response to interleukin-4;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0071866//negative regulation of apoptotic process in bone marrow cell;GO:0090068//positive regulation of cell cycle process;GO:0097043//histone H3-K56 acetylation;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:1902732//positive regulation of chondrocyte proliferation"	HMG
ENSG00000138796	28.136	28.049	27.582	29.648	29.474	26.309	1008	1001	719	770	884	670	HADH	hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Lipid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00310//Lysine degradation;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00062//Fatty acid elongation;ko00650//Butanoate metabolism"	K00022;K00022;K00022;K00022;K00022;K00022;K00022;K00022	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0070403//NAD+ binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0014823//response to activity;GO:0032868//response to insulin;GO:0046676//negative regulation of insulin secretion;GO:0050796//regulation of insulin secretion;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000138798	0.793	0.855	1.15	1.08	0.981	1.182	89	87	83	80	95	88	EGF	epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04630//JAK-STAT signaling pathway;ko05160//Hepatitis C;ko05224//Breast cancer;ko05226//Gastric cancer;ko04068//FoxO signaling pathway;ko04066//HIF-1 signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05213//Endometrial cancer;ko05219//Bladder cancer	K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357;K04357	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity	"GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002092//positive regulation of receptor internalization;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0030335//positive regulation of cell migration;GO:0038029//epidermal growth factor receptor signaling pathway via MAPK cascade;GO:0042327//positive regulation of phosphorylation;GO:0043388//positive regulation of DNA binding;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045740//positive regulation of DNA replication;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051048//negative regulation of secretion;GO:0051897//positive regulation of protein kinase B signaling;GO:0060749//mammary gland alveolus development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070371//ERK1 and ERK2 cascade;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090279//regulation of calcium ion import;GO:0090370//negative regulation of cholesterol efflux;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:1902966//positive regulation of protein localization to early endosome;GO:1905278//positive regulation of epithelial tube formation;GO:2000008//regulation of protein localization to cell surface;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000138801	29.084	27.447	29.483	29.448	27.249	32.221	1516	1438	1135	1137	1200	1222	PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:8603]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of other amino acids;Energy metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00450//Selenocompound metabolism;ko00920//Sulfur metabolism	K13811;K13811;K13811;K13811	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004020//adenylylsulfate kinase activity;GO:0004781//sulfate adenylyltransferase (ATP) activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042803//protein homodimerization activity	GO:0000103//sulfate assimilation;GO:0001501//skeletal system development;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	--
ENSG00000138802	15.083	12.987	12.739	11.807	12.26	11.728	1360	1149	843	794	918	763	SEC24B	"SEC24 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10704]"	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05130//Pathogenic Escherichia coli infection;ko04141//Protein processing in endoplasmic reticulum	K14007;K14007	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0070971//endoplasmic reticulum exit site	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001843//neural tube closure;GO:0002093//auditory receptor cell morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0021747//cochlear nucleus development;GO:0035909//aorta morphogenesis;GO:0060088//auditory receptor cell stereocilium organization;GO:0060425//lung morphogenesis;GO:0060463//lung lobe morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0072359//circulatory system development;GO:0090110//COPII-coated vesicle cargo loading;GO:0090178//regulation of establishment of planar polarity involved in neural tube closure;GO:1901301//regulation of cargo loading into COPII-coated vesicle	--
ENSG00000138813	0	0	0	0	0	0	0	0	0	0	0	0	C4orf17	chromosome 4 open reading frame 17 [Source:HGNC Symbol;Acc:HGNC:25274]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000138814	8.46	7.045	7.911	6.418	7.625	6.81	734	613	460	414	533	425	PPP3CA	protein phosphatase 3 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9314]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cell growth and death;Nervous system;Development and regeneration;Nervous system;Immune system;Immune system;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Substance dependence;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04380//Osteoclast differentiation;ko04724//Glutamatergic synapse;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04370//VEGF signaling pathway	K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348;K04348	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005955//calcineurin complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0036057//slit diaphragm;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0016018//cyclosporin A binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0051117//ATPase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0001975//response to amphetamine;GO:0006470//protein dephosphorylation;GO:0006606//protein import into nucleus;GO:0006816//calcium ion transport;GO:0007420//brain development;GO:0007568//aging;GO:0008544//epidermis development;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014883//transition between fast and slow fiber;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0016311//dephosphorylation;GO:0019722//calcium-mediated signaling;GO:0023057//negative regulation of signaling;GO:0030216//keratinocyte differentiation;GO:0030335//positive regulation of cell migration;GO:0033173//calcineurin-NFAT signaling cascade;GO:0033555//multicellular organismal response to stress;GO:0035562//negative regulation of chromatin binding;GO:0042060//wound healing;GO:0042104//positive regulation of activated T cell proliferation;GO:0042110//T cell activation;GO:0043403//skeletal muscle tissue regeneration;GO:0045669//positive regulation of osteoblast differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045785//positive regulation of cell adhesion;GO:0045807//positive regulation of endocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046676//negative regulation of insulin secretion;GO:0046878//positive regulation of saliva secretion;GO:0048741//skeletal muscle fiber development;GO:0050774//negative regulation of dendrite morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051592//response to calcium ion;GO:0060079//excitatory postsynaptic potential;GO:0061006//regulation of cell proliferation involved in kidney morphogenesis;GO:0070262//peptidyl-serine dephosphorylation;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071333//cellular response to glucose stimulus;GO:0090193//positive regulation of glomerulus development;GO:0097205//renal filtration;GO:0097720//calcineurin-mediated signaling;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903244//positive regulation of cardiac muscle hypertrophy in response to stress;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1905205//positive regulation of connective tissue replacement;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane	--
ENSG00000138821	8.308	7.861	6.769	8.452	8.284	8.296	542	519	322	408	461	387	SLC39A8	solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Cell growth and death	ko05010//Alzheimer disease;ko05012//Parkinson disease;ko04216//Ferroptosis	K14714;K14714;K14714	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031090//organelle membrane	GO:0005381//iron ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0015086//cadmium ion transmembrane transporter activity;GO:0015087//cobalt ion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015296//anion:cation symporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0097079//selenite:proton symporter activity;GO:0140412//zinc:bicarbonate symporter activity	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006487//protein N-linked glycosylation;GO:0006525//arginine metabolic process;GO:0006811//ion transport;GO:0006824//cobalt ion transport;GO:0006829//zinc ion transport;GO:0006876//cellular cadmium ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0030001//metal ion transport;GO:0030026//cellular manganese ion homeostasis;GO:0030198//extracellular matrix organization;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0061757//leukocyte adhesion to arterial endothelial cell;GO:0070574//cadmium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071578//zinc ion import across plasma membrane;GO:0097080//plasma membrane selenite transport;GO:0098711//iron ion import across plasma membrane;GO:1990079//cartilage homeostasis;GO:1990540//mitochondrial manganese ion transmembrane transport"	--
ENSG00000138823	0.06	0.076	0	0	0.054	0.057	2	5	0	0	3	1	MTTP	microsomal triglyceride transfer protein [Source:HGNC Symbol;Acc:HGNC:7467]	Organismal Systems	Digestive system	ko04975//Fat digestion and absorption	K14463	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0043235//receptor complex	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0034185//apolipoprotein binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0120013//lipid transfer activity;GO:0120014//phospholipid transfer activity;GO:0120019//phosphatidylcholine transfer activity;GO:0120020//cholesterol transfer activity;GO:0140344//triglyceride transfer activity;GO:1902388//ceramide 1-phosphate transfer activity;GO:1904121//phosphatidylethanolamine transfer activity	GO:0006497//protein lipidation;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0007623//circadian rhythm;GO:0009306//protein secretion;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0034197//triglyceride transport;GO:0034374//low-density lipoprotein particle remodeling;GO:0034377//plasma lipoprotein particle assembly;GO:0034378//chylomicron assembly;GO:0034379//very-low-density lipoprotein particle assembly;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0042953//lipoprotein transport;GO:0051592//response to calcium ion;GO:0120009//intermembrane lipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000138829	38.566	39.101	34.527	29.351	35.576	34.53	8648	8694	5680	4870	6667	5574	FBN2	fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity	GO:0009653//anatomical structure morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0030501//positive regulation of bone mineralization;GO:0035108//limb morphogenesis;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0043010//camera-type eye development;GO:0045669//positive regulation of osteoblast differentiation;GO:0048048//embryonic eye morphogenesis;GO:0060346//bone trabecula formation	--
ENSG00000138834	4.06	3.644	5.343	4.631	7.069	3.946	404	392	320	363	387	316	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:6884]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04436	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:1904115//axon cytoplasm	GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0008432//JUN kinase binding;GO:0019894//kinesin binding;GO:0030159//signaling receptor complex adaptor activity	GO:0016192//vesicle-mediated transport;GO:0031103//axon regeneration;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0046328//regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0050821//protein stabilization;GO:0061564//axon development;GO:0099641//anterograde axonal protein transport	--
ENSG00000138835	24.638	26.574	29.737	29.385	29.118	34.325	926	974	802	773	893	920	RGS3	regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07524	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000138867	12.488	12.098	11.834	10.457	11.62	12.98	778	775	537	501	634	557	GUCD1	guanylyl cyclase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14237]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000138892	0	0	0	0	0	0	0	0	0	0	0	0	TTLL8	tubulin tyrosine ligase like 8 [Source:HGNC Symbol;Acc:HGNC:34000]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070735//protein-glycine ligase activity;GO:0070736//protein-glycine ligase activity, initiating"	GO:0006464//cellular protein modification process;GO:0018094//protein polyglycylation;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly	--
ENSG00000138942	22.545	24.028	23.569	24.259	23.352	28.048	1488	1590	1145	1184	1299	1342	RNF185	ring finger protein 185 [Source:HGNC Symbol;Acc:HGNC:26783]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10666	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0043130//ubiquitin binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036503//ERAD pathway;GO:0044314//protein K27-linked ubiquitination;GO:0051607//defense response to virus;GO:0051865//protein autoubiquitination;GO:0055085//transmembrane transport;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0071712//ER-associated misfolded protein catabolic process;GO:1904294//positive regulation of ERAD pathway;GO:1904380//endoplasmic reticulum mannose trimming	--
ENSG00000138944	0.936	1.337	0.533	0.484	0.866	0.609	133	191	56	51	104	63	SHISAL1	shisa like 1 [Source:HGNC Symbol;Acc:HGNC:29335]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000138964	0	0	0	0	0	0	0	0	0	0	0	0	PARVG	parvin gamma [Source:HGNC Symbol;Acc:HGNC:14654]	Cellular Processes	Cellular community - eukaryotes	ko04510//Focal adhesion	K06275	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0030031//cell projection assembly;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading	--
ENSG00000139044	0.158	0.291	0.194	0.236	0.152	0.151	18	22	9	10	9	9	B4GALNT3	"beta-1,4-N-acetyl-galactosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:24137]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00513//Various types of N-glycan biosynthesis	K09656;K09656	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	-	--
ENSG00000139053	0	0	0	0	0	0	0	0	0	0	0	0	PDE6H	phosphodiesterase 6H [Source:HGNC Symbol;Acc:HGNC:8790]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13760;K13760	GO:0042622//photoreceptor outer segment membrane	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030553//cGMP binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007601//visual perception;GO:0043086//negative regulation of catalytic activity;GO:0043410//positive regulation of MAPK cascade;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus	--
ENSG00000139055	0.187	0	0.131	0	0.057	0.133	6	0	2	0	1	2	ERP27	endoplasmic reticulum protein 27 [Source:HGNC Symbol;Acc:HGNC:26495]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress	--
ENSG00000139083	1.051	1.171	0.903	0.816	1.133	1.025	134	150	85	77	122	95	ETV6	ETS variant transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:3495]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K03211	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007296//vitellogenesis;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071425//hematopoietic stem cell proliferation;GO:0097152//mesenchymal cell apoptotic process"	ETS
ENSG00000139112	47.146	48.645	55.058	56.406	48.095	52.167	1825	1782	1555	1575	1551	1416	GABARAPL1	GABA type A receptor associated protein like 1 [Source:HGNC Symbol;Acc:HGNC:4068]	Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Cellular Processes	Immune system;Transport and catabolism;Signal transduction;Nervous system;Transport and catabolism;Transport and catabolism	ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04727//GABAergic synapse;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K08341;K08341;K08341;K08341;K08341;K08341	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0030957//Tat protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0048487//beta-tubulin binding;GO:0050811//GABA receptor binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0016236//macroautophagy	--
ENSG00000139116	15.17	11.615	12.345	9.556	9.159	9.854	1450	1159	885	614	770	719	KIF21A	kinesin family member 21A [Source:HGNC Symbol;Acc:HGNC:19349]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity;GO:0071532//ankyrin repeat binding	GO:0007018//microtubule-based movement	--
ENSG00000139117	16.097	14.298	15.967	12.941	13.498	16.708	919	795	683	519	645	789	CPNE8	copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]	-	-	-	-	GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0071277//cellular response to calcium ion	--
ENSG00000139131	4.327	4.509	3.854	3.536	3.208	3.912	190	199	125	115	119	125	YARS2	tyrosyl-tRNA synthetase 2 [Source:HGNC Symbol;Acc:HGNC:24249]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01866	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004831//tyrosine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042803//protein homodimerization activity;GO:0072545//tyrosine binding	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006437//tyrosyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0070184//mitochondrial tyrosyl-tRNA aminoacylation	--
ENSG00000139132	13.133	8.847	11.07	8.149	8.939	9.305	1670	1176	974	749	949	915	FGD4	"FYVE, RhoGEF and PH domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19125]"	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0030032//lamellipodium assembly;GO:0030035//microspike assembly;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000139133	1.837	2.104	4.013	1.896	2.178	2.815	111	117	115.42	79.48	87	87	ALG10	"ALG10 alpha-1,2-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23162]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K03850;K03850	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106073//dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process	--
ENSG00000139144	0	0	0	0	0	0	0	0	0	0	0	0	PIK3C2G	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [Source:HGNC Symbol;Acc:HGNC:8973]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Infectious disease: bacterial;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05132//Salmonella infection;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00923;K00923;K00923;K00923	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016020//membrane;GO:0019898//extrinsic component of membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016740//transferase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0035091//phosphatidylinositol binding;GO:0052742//phosphatidylinositol kinase activity	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006935//chemotaxis;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0039694//viral RNA genome replication;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000139146	15.832	20.178	16.615	14.949	15.773	17.346	827	834	589	628	640	674	SINHCAF	SIN3-HDAC complex associated factor [Source:HGNC Symbol;Acc:HGNC:30702]	-	-	-	-	GO:0005634//nucleus;GO:0016580//Sin3 complex	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045596//negative regulation of cell differentiation;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance	--
ENSG00000139151	0	0	0	0	0	0	0	0	0	0	0	0	PLCZ1	phospholipase C zeta 1 [Source:HGNC Symbol;Acc:HGNC:19218]	Metabolism;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Cell growth and death;Endocrine system;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05131//Shigellosis;ko04114//Oocyte meiosis;ko04919//Thyroid hormone signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K05861;K05861;K05861;K05861;K05861;K05861;K05861	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045120//pronucleus;GO:0048471//perinuclear region of cytoplasm;GO:0061827//sperm head	"GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005509//calcium ion binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008081//phosphoric diester hydrolase activity;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016787//hydrolase activity;GO:0032266//phosphatidylinositol-3-phosphate binding"	GO:0006629//lipid metabolic process;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007338//single fertilization;GO:0007343//egg activation;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0060470//positive regulation of cytosolic calcium ion concentration involved in egg activation	--
ENSG00000139154	15.801	14.081	14.484	10.287	11.804	17.622	630	501	423	327	388	439	AEBP2	AE binding protein 2 [Source:HGNC Symbol;Acc:HGNC:24051]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000139155	0	0.019	0	0	0.069	0.019	0	1	0	0	3	1	SLCO1C1	solute carrier organic anion transporter family member 1C1 [Source:HGNC Symbol;Acc:HGNC:13819]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K08747	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport;GO:0150104//transport across blood-brain barrier;GO:2000611//positive regulation of thyroid hormone generation	--
ENSG00000139160	0.652	0.726	1.654	0.456	1.067	0.927	43.88	43.69	51.45	22.18	39.5	41.12	ETFBKMT	electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0032991//protein-containing complex	GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation;GO:1904733//negative regulation of electron transfer activity;GO:1904736//negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	--
ENSG00000139163	14.452	13.037	12.306	11.189	12.989	14.079	1627	1135	914	772	967	1047	ETNK1	ethanolamine kinase 1 [Source:HGNC Symbol;Acc:HGNC:24649]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K00894;K00894	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004305//ethanolamine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000139168	24.858	20.798	20.982	19.194	22.918	20.545	649	508	378	346	469	369	ZCRB1	zinc finger CCHC-type and RNA binding motif containing 1 [Source:HGNC Symbol;Acc:HGNC:29620]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000139173	12.679	11.184	15.65	10.774	10.302	11.153	676	640	510	453	496	466	TMEM117	transmembrane protein 117 [Source:HGNC Symbol;Acc:HGNC:25308]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	--
ENSG00000139174	3.327	3.52	4.086	5.151	3.719	6.235	268.73	286.58	237.21	237.71	249.99	311	PRICKLE1	prickle planar cell polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:17019]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04511	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0001843//neural tube closure;GO:0006606//protein import into nucleus;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035904//aorta development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060976//coronary vasculature development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000691//negative regulation of cardiac muscle cell myoblast differentiation"	--
ENSG00000139178	32.21	29.34	30.258	24.702	30.318	31.494	1634.32	1486.41	1283.84	977.99	1238.55	1220.33	C1RL	complement C1r subcomponent like [Source:HGNC Symbol;Acc:HGNC:21265]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006958//complement activation, classical pathway;GO:0031638//zymogen activation;GO:0045087//innate immune response"	--
ENSG00000139180	2.963	3.708	2.594	2.91	2.553	3.366	414.16	472.1	332.09	348.78	373.85	347.88	NDUFA9	NADH:ubiquinone oxidoreductase subunit A9 [Source:HGNC Symbol;Acc:HGNC:7693]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0003824//catalytic activity;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0044877//protein-containing complex binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006814//sodium ion transport;GO:0007623//circadian rhythm;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:1901006//ubiquinone-6 biosynthetic process"	--
ENSG00000139182	60.109	57.628	56.581	56.45	52.862	51.274	3653	3934	2878	2872	3298	2672	CLSTN3	calsyntenin 3 [Source:HGNC Symbol;Acc:HGNC:18371]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0001540//amyloid-beta binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0042988//X11-like protein binding	"GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0035249//synaptic transmission, glutamatergic;GO:0050806//positive regulation of synaptic transmission;GO:0051932//synaptic transmission, GABAergic;GO:0051965//positive regulation of synapse assembly;GO:1902474//positive regulation of protein localization to synapse;GO:1905606//regulation of presynapse assembly"	--
ENSG00000139187	0.378	0.205	0.271	0.313	0.591	0.228	11	8	6	9	8	6	KLRG1	killer cell lectin like receptor G1 [Source:HGNC Symbol;Acc:HGNC:6380]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007166//cell surface receptor signaling pathway;GO:0045087//innate immune response	--
ENSG00000139190	1.007	0.634	1.06	1.177	1.599	1.003	50	34	39	44	53	45	VAMP1	vesicle associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:12642]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08510	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0035579//specific granule membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070821//tertiary granule membrane;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0035493//SNARE complex assembly	--
ENSG00000139192	0.866	0.35	0.44	0.731	0.545	0.521	32	13	12	20	17	14	TAPBPL	TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0023024//MHC class I protein complex binding	GO:0002376//immune system process;GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0002590//negative regulation of antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response	--
ENSG00000139193	0.194	0.039	0.052	0.052	0.046	0.16	5	1	1	1	1	3	CD27	CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05144	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0016064//immunoglobulin mediated immune response;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045579//positive regulation of B cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0046330//positive regulation of JNK cascade;GO:0070233//negative regulation of T cell apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000139194	0.403	0.401	0.205	0.272	0.358	0.485	8	8	3	4	6	7	RBP5	retinol binding protein 5 [Source:HGNC Symbol;Acc:HGNC:15847]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding	GO:0015908//fatty acid transport	--
ENSG00000139197	37.065	35.864	41.178	36.062	33.082	39.559	1987	1993	1505	1324	1378	1496	PEX5	peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13342	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0000268//peroxisome targeting sequence binding;GO:0005052//peroxisome matrix targeting signal-1 binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0031267//small GTPase binding;GO:0033328//peroxisome membrane targeting sequence binding;GO:0047485//protein N-terminus binding;GO:0140311//protein sequestering activity	"GO:0000038//very long-chain fatty acid metabolic process;GO:0001764//neuron migration;GO:0006625//protein targeting to peroxisome;GO:0006635//fatty acid beta-oxidation;GO:0007005//mitochondrion organization;GO:0007006//mitochondrial membrane organization;GO:0007029//endoplasmic reticulum organization;GO:0007031//peroxisome organization;GO:0015031//protein transport;GO:0016558//protein import into peroxisome matrix;GO:0016560//protein import into peroxisome matrix, docking;GO:0016561//protein import into peroxisome matrix, translocation;GO:0021795//cerebral cortex cell migration;GO:0021895//cerebral cortex neuron differentiation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0040018//positive regulation of multicellular organism growth;GO:0044255//cellular lipid metabolic process;GO:0045046//protein import into peroxisome membrane;GO:0048468//cell development;GO:0050905//neuromuscular process;GO:0051262//protein tetramerization"	--
ENSG00000139200	17.047	18.346	24.349	18.39	21.085	23.109	923	1001	767	737	946	937	PIANP	PILR alpha associated neural protein [Source:HGNC Symbol;Acc:HGNC:25338]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding	GO:0050776//regulation of immune response	--
ENSG00000139209	0.076	0.278	0.199	0.069	0.06	0.017	6	11	8	4	4	1	SLC38A4	solute carrier family 38 member 4 [Source:HGNC Symbol;Acc:HGNC:14679]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport	--
ENSG00000139211	3.932	3.65	1.71	1.441	1.161	1.948	265	242	84	73	69	96	AMIGO2	adhesion molecule with Ig like domain 2 [Source:HGNC Symbol;Acc:HGNC:24073]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007420//brain development;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0051965//positive regulation of synapse assembly	--
ENSG00000139218	12.248	8.847	9.277	5.586	7.713	7.613	1343	852	585	379	650	541	SCAF11	SR-related CTD associated factor 11 [Source:HGNC Symbol;Acc:HGNC:10784]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000139219	0.164	0.303	0.147	0.117	0.034	0.092	17	32	10	8	3	7	COL2A1	collagen type II alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2200]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K19719;K19719;K19719;K19719;K19719	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005585//collagen type II trimer;GO:0005592//collagen type XI trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0042289//MHC class II protein binding;GO:0042802//identical protein binding;GO:0043394//proteoglycan binding;GO:0046872//metal ion binding;GO:0048407//platelet-derived growth factor binding	GO:0001501//skeletal system development;GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0001894//tissue homeostasis;GO:0001958//endochondral ossification;GO:0002062//chondrocyte differentiation;GO:0003007//heart morphogenesis;GO:0006029//proteoglycan metabolic process;GO:0007417//central nervous system development;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0010468//regulation of gene expression;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030903//notochord development;GO:0035108//limb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048839//inner ear development;GO:0051216//cartilage development;GO:0060021//roof of mouth development;GO:0060174//limb bud formation;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060348//bone development;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0071599//otic vesicle development;GO:0071773//cellular response to BMP stimulus;GO:0097065//anterior head development;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000139220	0.017	0.165	0.269	0.109	0.199	0	1	5	3	5	2	0	PPFIA2	PTPRF interacting protein alpha 2 [Source:HGNC Symbol;Acc:HGNC:9246]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009986//cell surface;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007160//cell-matrix adhesion;GO:0050808//synapse organization;GO:0060998//regulation of dendritic spine development;GO:0061001//regulation of dendritic spine morphogenesis;GO:0099519//dense core granule cytoskeletal transport	--
ENSG00000139223	0	0	0	0	0	0	0	0	0	0	0	0	ANP32D	acidic nuclear phosphoprotein 32 family member D [Source:HGNC Symbol;Acc:HGNC:16676]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000139233	8.334	8.504	7.051	7.574	6.225	6.624	329	303	183	208.64	204	182.8	LLPH	"LLP homolog, long-term synaptic facilitation factor [Source:HGNC Symbol;Acc:HGNC:28229]"	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0001099//basal RNA polymerase II transcription machinery binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0060999//positive regulation of dendritic spine development;GO:0097484//dendrite extension	--
ENSG00000139263	4.968	5.05	5.731	5.883	5.199	4.516	412	426	342	332	363	264	LRIG3	leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031012//extracellular matrix;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0032474//otolith morphogenesis	--
ENSG00000139266	8.775	8.355	9.645	8.84	8.725	11.459	425	423	326	321	339	392	MARCHF9	membrane associated ring-CH-type finger 9 [Source:HGNC Symbol;Acc:HGNC:25139]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000139269	0.118	0.039	0	0.053	0.023	0	6	2	0	2	1	0	INHBE	inhibin subunit beta E [Source:HGNC Symbol;Acc:HGNC:24029]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K22689;K22689;K22689	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0008083//growth factor activity	GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction	--
ENSG00000139278	2.732	2.538	1.51	0.59	1.485	1.634	242.95	239.73	85.82	52.66	80.83	64.93	GLIPR1	GLI pathogenesis related 1 [Source:HGNC Symbol;Acc:HGNC:17001]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane	GO:0005515//protein binding	-	--
ENSG00000139287	0	0	0	0	0	0	0	0	0	0	0	0	TPH2	tryptophan hydroxylase 2 [Source:HGNC Symbol;Acc:HGNC:20692]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Nervous system;Amino acid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko00380//Tryptophan metabolism;ko00790//Folate biosynthesis	K00502;K00502;K00502;K00502	GO:0005829//cytosol;GO:0043005//neuron projection	"GO:0004497//monooxygenase activity;GO:0004510//tryptophan 5-monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046872//metal ion binding"	GO:0007623//circadian rhythm;GO:0009072//aromatic amino acid family metabolic process;GO:0014823//response to activity;GO:0031667//response to nutrient levels;GO:0042427//serotonin biosynthetic process;GO:0043627//response to estrogen;GO:0051384//response to glucocorticoid;GO:0051592//response to calcium ion;GO:0071285//cellular response to lithium ion	--
ENSG00000139289	7.764	6.936	6.701	5.24	4.744	5.718	934	833	595	466	482	503	PHLDA1	pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0045210//FasL biosynthetic process	--
ENSG00000139291	9.736	14.037	15.127	15.207	11.766	18.035	1043	1001	845	747	854	777	TMEM19	transmembrane protein 19 [Source:HGNC Symbol;Acc:HGNC:25605]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000139292	0.036	0.036	0	0.024	0	0.052	3	2	0	1	0	3	LGR5	leucine rich repeat containing G protein-coupled receptor 5 [Source:HGNC Symbol;Acc:HGNC:4504]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04308	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity	GO:0001942//hair follicle development;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0009755//hormone-mediated signaling pathway;GO:0009994//oocyte differentiation;GO:0042127//regulation of cell population proliferation;GO:0048839//inner ear development;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis	--
ENSG00000139304	0.083	0.023	0.064	0.056	0.055	0.081	14	4	8	7	8	10	PTPRQ	protein tyrosine phosphatase receptor type Q [Source:HGNC Symbol;Acc:HGNC:9679]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032421//stereocilium bundle;GO:0062023//collagen-containing extracellular matrix	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016791//phosphatase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042472//inner ear morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060116//vestibular receptor cell morphogenesis	--
ENSG00000139318	0.585	0.639	1.457	0.557	1.526	1.98	44	31	50	26	56	55	DUSP6	dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]	Environmental Information Processing;Human Diseases;Human Diseases	Signal transduction;Cancer: overview;Cancer: specific types	ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko05221//Acute myeloid leukemia	K21946;K21946;K21946	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010942//positive regulation of cell death;GO:0014070//response to organic cyclic compound;GO:0016311//dephosphorylation;GO:0030154//cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0051409//response to nitrosative stress;GO:0060420//regulation of heart growth;GO:0070371//ERK1 and ERK2 cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070848//response to growth factor	--
ENSG00000139323	5.225	5.81	5.574	4.765	4.077	5.459	294	269.89	215	143	181.88	202	POC1B	POC1 centriolar protein B [Source:HGNC Symbol;Acc:HGNC:30836]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001895//retina homeostasis;GO:0007099//centriole replication;GO:0008283//cell population proliferation;GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000139324	3.682	2.628	2.896	1.955	2.261	2.901	517	394	279	216	285	293	TMTC3	transmembrane O-mannosyltransferase targeting cadherins 3 [Source:HGNC Symbol;Acc:HGNC:26899]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006486//protein glycosylation;GO:0034976//response to endoplasmic reticulum stress;GO:0035269//protein O-linked mannosylation;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000139329	40.703	43.26	10.509	5.434	10.383	6.028	2255	2409	430	223	486	243	LUM	lumican [Source:HGNC Symbol;Acc:HGNC:6724]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K08122	GO:0005576//extracellular region;GO:0005583//fibrillar collagen trimer;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0007601//visual perception;GO:0030199//collagen fibril organization;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000139330	0	0	0	0	0	0	0	0	0	0	0	0	KERA	keratocan [Source:HGNC Symbol;Acc:HGNC:6309]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0061303//cornea development in camera-type eye	--
ENSG00000139343	20.984	15.148	23.107	21.023	16.27	20.191	197	143	160	146	129	138	SNRPF	small nuclear ribonucleoprotein polypeptide F [Source:HGNC Symbol;Acc:HGNC:11162]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11098	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005683//U7 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000139344	0.105	0.052	0	0.088	0.395	0	4	2	0	3	6.8	0	AMDHD1	amidohydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28577]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K01468;K01468	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003674//molecular_function;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0046872//metal ion binding;GO:0050480//imidazolonepropionase activity"	GO:0006547//histidine metabolic process;GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate	--
ENSG00000139350	6.987	6.84	4.5	5.003	4.907	5.536	394	359	202	188	231	226	NEDD1	NEDD1 gamma-tubulin ring complex targeting factor [Source:HGNC Symbol;Acc:HGNC:7723]	-	-	-	-	GO:0000242//pericentriolar material;GO:0000922//spindle pole;GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0045177//apical part of cell	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division;GO:0071539//protein localization to centrosome	--
ENSG00000139351	0	0	0	0	0	0	0	0	0	0	0	0	SYCP3	synaptonemal complex protein 3 [Source:HGNC Symbol;Acc:HGNC:18130]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K19528	"GO:0000775//chromosome, centromeric region;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005694//chromosome"	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0007049//cell cycle;GO:0007141//male meiosis I;GO:0007286//spermatid development;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0051301//cell division;GO:0051321//meiotic cell cycle"	--
ENSG00000139352	17.703	14.422	16.207	6.165	7.682	9.588	911	746	616	235	334	359	ASCL1	achaete-scute family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:738]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0003358//noradrenergic neuron development;GO:0003359//noradrenergic neuron fate commitment;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007346//regulation of mitotic cell cycle;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007400//neuroblast fate determination;GO:0007405//neuroblast proliferation;GO:0007423//sensory organ development;GO:0007507//heart development;GO:0008593//regulation of Notch signaling pathway;GO:0010001//glial cell differentiation;GO:0010226//response to lithium ion;GO:0010468//regulation of gene expression;GO:0014003//oligodendrocyte development;GO:0021527//spinal cord association neuron differentiation;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0021750//vestibular nucleus development;GO:0021779//oligodendrocyte cell fate commitment;GO:0021879//forebrain neuron differentiation;GO:0021892//cerebral cortex GABAergic interneuron differentiation;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030856//regulation of epithelial cell differentiation;GO:0032526//response to retinoic acid;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048485//sympathetic nervous system development;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048666//neuron development;GO:0048699//generation of neurons;GO:0048709//oligodendrocyte differentiation;GO:0050767//regulation of neurogenesis;GO:0050769//positive regulation of neurogenesis;GO:0050883//musculoskeletal movement, spinal reflex action;GO:0051593//response to folic acid;GO:0060163//subpallium neuron fate commitment;GO:0060165//regulation of timing of subpallium neuron differentiation;GO:0060166//olfactory pit development;GO:0060487//lung epithelial cell differentiation;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0061100//lung neuroendocrine cell differentiation;GO:0061102//stomach neuroendocrine cell differentiation;GO:0061103//carotid body glomus cell differentiation;GO:0061104//adrenal chromaffin cell differentiation;GO:0061549//sympathetic ganglion development;GO:0070849//response to epidermal growth factor;GO:0071259//cellular response to magnetism;GO:2000179//positive regulation of neural precursor cell proliferation"	bHLH
ENSG00000139354	1.275	0.578	0.561	0.778	0.891	0.977	73	53	29	38	48	64	GAS2L3	growth arrest specific 2 like 3 [Source:HGNC Symbol;Acc:HGNC:27475]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal anchor activity;GO:0051015//actin filament binding	GO:0000226//microtubule cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0051764//actin crosslink formation	--
ENSG00000139364	0.265	0.247	0.281	0.233	0.19	0.252	60	58	47	40	36	43	TMEM132B	transmembrane protein 132B [Source:HGNC Symbol;Acc:HGNC:29397]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000139370	14.248	14.226	15.473	13.294	14.625	13.281	789	791	635	555	692	540	SLC15A4	solute carrier family 15 member 4 [Source:HGNC Symbol;Acc:HGNC:23090]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031303//integral component of endosome membrane;GO:0031901//early endosome membrane;GO:0035579//specific granule membrane;GO:0036020//endolysosome membrane;GO:1905103//integral component of lysosomal membrane	GO:0005290//L-histidine transmembrane transporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015333//peptide:proton symporter activity;GO:0015647//peptidoglycan transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0071916//dipeptide transmembrane transporter activity	GO:0002376//immune system process;GO:0006811//ion transport;GO:0006857//oligopeptide transport;GO:0015031//protein transport;GO:0015817//histidine transport;GO:0015833//peptide transport;GO:0015835//peptidoglycan transport;GO:0033023//mast cell homeostasis;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0034161//positive regulation of toll-like receptor 8 signaling pathway;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0055085//transmembrane transport;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0070430//positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0089708//L-histidine transmembrane export from vacuole;GO:0140206//dipeptide import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000139372	8.856	7.525	7.306	6.116	6.083	6.748	530	442	290	253	280	282	TDG	thymine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:11700]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K20813	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016605//PML body	GO:0000287//magnesium ion binding;GO:0000700//mismatch base pair DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0004844//uracil DNA N-glycosylase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008263//pyrimidine-specific mismatch base pair DNA N-glycosylase activity;GO:0016787//hydrolase activity;GO:0019104//DNA N-glycosylase activity;GO:0019904//protein domain specific binding;GO:0030983//mismatched DNA binding;GO:0031402//sodium ion binding;GO:0031404//chloride ion binding;GO:0032183//SUMO binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0043739//G/U mismatch-specific uracil-DNA glycosylase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006285//base-excision repair, AP site formation;GO:0006298//mismatch repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0032091//negative regulation of protein binding;GO:0035511//oxidative DNA demethylation;GO:0035562//negative regulation of chromatin binding;GO:0040029//regulation of gene expression, epigenetic;GO:0045008//depyrimidination;GO:0045995//regulation of embryonic development;GO:0080111//DNA demethylation;GO:1902544//regulation of DNA N-glycosylase activity"	--
ENSG00000139405	18.18	18.602	20.099	20.699	20.666	19.97	713	727	577	599	684	564	RITA1	RBPJ interacting and tubulin associated 1 [Source:HGNC Symbol;Acc:HGNC:25925]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0015631//tubulin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0045746//negative regulation of Notch signaling pathway;GO:0051168//nuclear export	--
ENSG00000139410	1.957	2.828	2.949	4.236	3.102	2.761	53	77	59	85	71	55	SDSL	serine dehydratase like [Source:HGNC Symbol;Acc:HGNC:30404]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism;ko00290//Valine, leucine and isoleucine biosynthesis"	K17989;K17989;K17989;K17989;K17989;K17989	GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003941//L-serine ammonia-lyase activity;GO:0004794//L-threonine ammonia-lyase activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006520//cellular amino acid metabolic process;GO:0006567//threonine catabolic process;GO:0006629//lipid metabolic process;GO:0008150//biological_process;GO:0009097//isoleucine biosynthetic process	--
ENSG00000139428	19.857	21.462	19.009	23.206	24.469	25.659	615	646.09	454	540	649	546	MMAB	metabolism of cobalamin associated B [Source:HGNC Symbol;Acc:HGNC:19331]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K00798;K00798	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008817//cob(I)yrinic acid a,c-diamide adenosyltransferase activity;GO:0016740//transferase activity;GO:0031419//cobalamin binding"	GO:0009235//cobalamin metabolic process	--
ENSG00000139433	14.301	14.089	13.86	12.249	14.277	12.458	695	702	489	453	597	447	GLTP	glycolipid transfer protein [Source:HGNC Symbol;Acc:HGNC:24867]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0017089//glycolipid transfer activity;GO:0042802//identical protein binding;GO:0051861//glycolipid binding;GO:0120013//lipid transfer activity;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0006687//glycosphingolipid metabolic process;GO:0006869//lipid transport;GO:0035627//ceramide transport;GO:0046836//glycolipid transport;GO:0120009//intermembrane lipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000139436	10.79	11.263	10.793	9.057	11.415	9.683	1139	1163	785	751	986	772	GIT2	GIT ArfGAP 2 [Source:HGNC Symbol;Acc:HGNC:4273]	Cellular Processes;Human Diseases	Transport and catabolism;Infectious disease: bacterial	ko04144//Endocytosis;ko05135//Yersinia infection	K12487;K12487	GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0110165//cellular anatomical entity	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0046872//metal ion binding	GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010646//regulation of cell communication;GO:0016310//phosphorylation;GO:0023051//regulation of signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000139437	4.88	4.647	4.617	3.96	4.424	4.152	310	287	219	185	240	194	TCHP	trichoplein keratin filament binding [Source:HGNC Symbol;Acc:HGNC:28135]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0045095//keratin filament;GO:0045179//apical cortex	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0030030//cell projection organization;GO:0030308//negative regulation of cell growth;GO:1902018//negative regulation of cilium assembly	--
ENSG00000139438	9.151	8.897	10.928	10.992	11.545	12.587	652	657	560	592	704	700	FAM222A	family with sequence similarity 222 member A [Source:HGNC Symbol;Acc:HGNC:25915]	-	-	-	-	-	-	-	--
ENSG00000139445	0.746	0.533	0.447	0.152	0.184	0.067	36	28	21	8	11	3	FOXN4	forkhead box N4 [Source:HGNC Symbol;Acc:HGNC:21399]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001947//heart looping;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0008016//regulation of heart contraction;GO:0010842//retina layer formation;GO:0021514//ventral spinal cord interneuron differentiation;GO:0030154//cell differentiation;GO:0035881//amacrine cell differentiation;GO:0036302//atrioventricular canal development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048663//neuron fate commitment;GO:0060579//ventral spinal cord interneuron fate commitment"	Fork_head
ENSG00000139496	10.927	9.509	9.6	7.477	10.139	9.585	1034	916	636	535	703	681	NUP58	nucleoporin 58 [Source:HGNC Symbol;Acc:HGNC:20261]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14307;K14307	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0042306//regulation of protein import into nucleus;GO:0051028//mRNA transport	--
ENSG00000139505	6.388	4.846	4.784	4.159	3.825	4.882	678	517	375	327	343	377	MTMR6	myotubularin related protein 6 [Source:HGNC Symbol;Acc:HGNC:7453]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18083;K18083;K18083	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0052866//phosphatidylinositol phosphate phosphatase activity;GO:0106018//phosphatidylinositol-3,5-bisphosphate phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006897//endocytosis;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000139508	9.986	9.91	10.527	11.187	9.489	11.389	681	651	519	561	541	543	SLC46A3	solute carrier family 46 member 3 [Source:HGNC Symbol;Acc:HGNC:27501]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:1905103//integral component of lysosomal membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0034486//vacuolar transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000139514	18.797	20.086	19.104	18.055	18.022	26.611	2863	3075	2149	2037	2319	2949	SLC7A1	solute carrier family 7 member 1 [Source:HGNC Symbol;Acc:HGNC:11057]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K13863	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0032991//protein-containing complex	GO:0000064//L-ornithine transmembrane transporter activity;GO:0005290//L-histidine transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015189//L-lysine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006865//amino acid transport;GO:0015807//L-amino acid transport;GO:0015819//lysine transport;GO:0015822//ornithine transport;GO:0042102//positive regulation of T cell proliferation;GO:0055085//transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:0097638//L-arginine import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903352//L-ornithine transmembrane transport;GO:1903401//L-lysine transmembrane transport;GO:1903810//L-histidine import across plasma membrane;GO:1903826//arginine transmembrane transport	--
ENSG00000139515	0	0	0	0	0	0	0	0	0	0	0	0	PDX1	pancreatic and duodenal homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6107]	Organismal Systems;Human Diseases;Human Diseases	Endocrine system;Endocrine and metabolic disease;Endocrine and metabolic disease	ko04911//Insulin secretion;ko04930//Type II diabetes mellitus;ko04950//Maturity onset diabetes of the young	K07594;K07594;K07594	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001889//liver development;GO:0003309//type B pancreatic cell differentiation;GO:0006006//glucose metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0007263//nitric oxide mediated signal transduction;GO:0007417//central nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009749//response to glucose;GO:0009887//animal organ morphogenesis;GO:0010040//response to iron(II) ion;GO:0010157//response to chlorate;GO:0010260//animal organ senescence;GO:0010468//regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0014070//response to organic cyclic compound;GO:0016331//morphogenesis of embryonic epithelium;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0031016//pancreas development;GO:0031017//exocrine pancreas development;GO:0031018//endocrine pancreas development;GO:0031100//animal organ regeneration;GO:0031667//response to nutrient levels;GO:0032024//positive regulation of insulin secretion;GO:0033273//response to vitamin;GO:0033993//response to lipid;GO:0034097//response to cytokine;GO:0035094//response to nicotine;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0043201//response to leucine;GO:0043279//response to alkaloid;GO:0043388//positive regulation of DNA binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:0048863//stem cell differentiation;GO:0051384//response to glucocorticoid;GO:0051594//detection of glucose;GO:0060290//transdifferentiation;GO:0070542//response to fatty acid;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2000675//negative regulation of type B pancreatic cell apoptotic process"	Homeobox
ENSG00000139517	13.235	11.32	9.997	8.848	9.062	9.631	1304	1121	726	644	752	684	LNX2	ligand of numb-protein X 2 [Source:HGNC Symbol;Acc:HGNC:20421]	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000139531	11.995	13.819	14.626	17.301	15.774	16.165	563	647	475	602	627	515	SUOX	sulfite oxidase [Source:HGNC Symbol;Acc:HGNC:11460]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K00387;K00387	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0008482//sulfite oxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0030151//molybdenum ion binding;GO:0043546//molybdopterin cofactor binding;GO:0046872//metal ion binding	GO:0006790//sulfur compound metabolic process	--
ENSG00000139537	0.995	1.606	0.959	0.406	0.191	0.411	37	60	27	13	6	11	CCDC65	coiled-coil domain containing 65 [Source:HGNC Symbol;Acc:HGNC:29937]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0003674//molecular_function	GO:0003352//regulation of cilium movement;GO:0060271//cilium assembly;GO:0060285//cilium-dependent cell motility;GO:0070286//axonemal dynein complex assembly	--
ENSG00000139540	0.024	0	0	0.075	0.131	0.228	1	0	0	1	2	3	SLC39A5	solute carrier family 39 member 5 [Source:HGNC Symbol;Acc:HGNC:20502]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14711;K14711	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	"GO:0001654//eye development;GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0030509//BMP signaling pathway;GO:0034224//cellular response to zinc ion starvation;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0055085//transmembrane transport;GO:0061351//neural precursor cell proliferation;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0071578//zinc ion import across plasma membrane"	--
ENSG00000139546	8.201	9.081	9.37	10.872	9.726	13.055	254	288	215	251	260	283	TARBP2	TARBP2 subunit of RISC loading complex [Source:HGNC Symbol;Acc:HGNC:11569]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0016604//nuclear body;GO:0048471//perinuclear region of cytoplasm;GO:0070578//RISC-loading complex	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035197//siRNA binding;GO:0035198//miRNA binding;GO:0036002//pre-mRNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0070883//pre-miRNA binding	GO:0006417//regulation of translation;GO:0006469//negative regulation of protein kinase activity;GO:0007286//spermatid development;GO:0007338//single fertilization;GO:0030422//production of siRNA involved in RNA interference;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035087//siRNA loading onto RISC involved in RNA interference;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035264//multicellular organism growth;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0043403//skeletal muscle tissue regeneration;GO:0045070//positive regulation of viral genome replication;GO:0045727//positive regulation of translation;GO:0046782//regulation of viral transcription;GO:0050689//negative regulation of defense response to virus by host;GO:0051149//positive regulation of muscle cell differentiation;GO:0061351//neural precursor cell proliferation;GO:0090065//regulation of production of siRNA involved in RNA interference;GO:1903798//regulation of production of miRNAs involved in gene silencing by miRNA	--
ENSG00000139547	0.17	0.056	0.077	0	0	0.078	6	2	2	0	0	2	RDH16	retinol dehydrogenase 16 [Source:HGNC Symbol;Acc:HGNC:29674]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11154;K11154	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004745//NAD-retinol dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0047023//androsterone dehydrogenase activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0022900//electron transport chain;GO:0042572//retinol metabolic process	--
ENSG00000139549	0.041	0	0	0.014	0	0.057	4	0	0	1	0	4	DHH	desert hedgehog signaling molecule [Source:HGNC Symbol;Acc:HGNC:2865]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K11990	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005113//patched binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001649//osteoblast differentiation;GO:0001708//cell fate specification;GO:0006508//proteolysis;GO:0007224//smoothened signaling pathway;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007286//spermatid development;GO:0010468//regulation of gene expression;GO:0016540//protein autoprocessing;GO:0030238//male sex determination;GO:0032355//response to estradiol;GO:0033327//Leydig cell differentiation;GO:0042552//myelination;GO:0043627//response to estrogen;GO:0050810//regulation of steroid biosynthetic process	--
ENSG00000139567	0.036	0.156	0.293	0.016	0.091	0.016	1	4	3	1	3	1	ACVRL1	activin A receptor like type 1 [Source:HGNC Symbol;Acc:HGNC:175]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K13594	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0070724//BMP receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016361//activin receptor activity, type I;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0043167//ion binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding;GO:0098821//BMP receptor activity"	"GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001936//regulation of endothelial cell proliferation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001946//lymphangiogenesis;GO:0001955//blood vessel maturation;GO:0001974//blood vessel remodeling;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007507//heart development;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0009953//dorsal/ventral pattern formation;GO:0010596//negative regulation of endothelial cell migration;GO:0010604//positive regulation of macromolecule metabolic process;GO:0010629//negative regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032924//activin receptor signaling pathway;GO:0035313//wound healing, spreading of epidermal cells;GO:0035912//dorsal aorta morphogenesis;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0051173//positive regulation of nitrogen compound metabolic process;GO:0051239//regulation of multicellular organismal process;GO:0051895//negative regulation of focal adhesion assembly;GO:0060836//lymphatic endothelial cell differentiation;GO:0060840//artery development;GO:0060841//venous blood vessel development;GO:0061154//endothelial tube morphogenesis;GO:0061298//retina vasculature development in camera-type eye;GO:0071363//cellular response to growth factor stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071773//cellular response to BMP stimulus;GO:2000279//negative regulation of DNA biosynthetic process"	--
ENSG00000139572	0	0.024	0	0	0	0	0	1	0	0	0	0	GPR84	G protein-coupled receptor 84 [Source:HGNC Symbol;Acc:HGNC:4535]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043235//receptor complex;GO:0070821//tertiary granule membrane	GO:0001604//urotensin II receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008150//biological_process	--
ENSG00000139574	0	0	0	0	0	0	0	0	0	0	0	0	NPFF	neuropeptide FF-amide peptide precursor [Source:HGNC Symbol;Acc:HGNC:7901]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05247	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0098794//postsynapse	GO:0001664//G protein-coupled receptor binding;GO:0005102//signaling receptor binding;GO:0005184//neuropeptide hormone activity	GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0060079//excitatory postsynaptic potential	--
ENSG00000139579	9.53	11.323	13.205	10.824	11.848	9.725	269	340	272	232	283	220	NABP2	nucleic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:28412]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035861//site of double-strand break;GO:0070876//SOSS complex"	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0070182//DNA polymerase binding;GO:0098505//G-rich strand telomeric DNA binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint;GO:0070200//establishment of protein localization to telomere;GO:1904355//positive regulation of telomere capping	--
ENSG00000139597	12.184	10.221	9.617	8.642	9.721	9.666	389	324	248	197	250	209	N4BP2L1	NEDD4 binding protein 2 like 1 [Source:HGNC Symbol;Acc:HGNC:25037]	-	-	-	-	-	-	-	--
ENSG00000139610	0	0	0	0	0	0	0	0	0	0	0	0	CELA1	chymotrypsin like elastase 1 [Source:HGNC Symbol;Acc:HGNC:3308]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:0009791//post-embryonic development;GO:0016055//Wnt signaling pathway;GO:0031017//exocrine pancreas development;GO:0035264//multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0045595//regulation of cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048771//tissue remodeling;GO:0055123//digestive system development;GO:0060309//elastin catabolic process;GO:0061113//pancreas morphogenesis	--
ENSG00000139613	29.298	32.987	33.858	28.868	30.637	30.788	2672.42	3036	2292.82	1953	2364	2018	SMARCC2	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 [Source:HGNC Symbol;Acc:HGNC:11105]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11649;K11649	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140092//bBAF complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0042393//histone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	MYB
ENSG00000139618	0.16	0.094	0.044	0.11	0.053	0.006	39	23	8	11	11	1	BRCA2	BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Cancer: specific types;Cancer: specific types;Replication and repair;Replication and repair	ko05200//Pathways in cancer;ko05224//Breast cancer;ko05212//Pancreatic cancer;ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K08775;K08775;K08775;K08775;K08775	"GO:0000152//nuclear ubiquitin ligase complex;GO:0000781//chromosome, telomeric region;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030141//secretory granule;GO:0032991//protein-containing complex;GO:0033593//BRCA2-MAGE-D1 complex;GO:1990391//DNA repair complex"	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0010484//H3 histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0042802//identical protein binding;GO:0043015//gamma-tubulin binding	"GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0001556//oocyte maturation;GO:0001833//inner cell mass cell proliferation;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0007569//cell aging;GO:0008283//cell population proliferation;GO:0008585//female gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010165//response to X-ray;GO:0010225//response to UV-C;GO:0010332//response to gamma radiation;GO:0030097//hemopoiesis;GO:0032465//regulation of cytokinesis;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0035518//histone H2A monoubiquitination;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043009//chordate embryonic development;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle;GO:0048478//replication fork protection;GO:0051276//chromosome organization;GO:0051298//centrosome duplication;GO:0051865//protein autoubiquitination;GO:0070200//establishment of protein localization to telomere;GO:0071479//cellular response to ionizing radiation;GO:1990426//mitotic recombination-dependent replication fork processing;GO:2000001//regulation of DNA damage checkpoint"	--
ENSG00000139620	11.276	8.93	8.272	8.028	9.099	9.315	420	331	251	248	280	298	KANSL2	KAT8 regulatory NSL complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:26024]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0044545//NSL complex	GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000139624	25.462	25.473	26.891	26.283	27.317	30.184	1212	1235	989	972	1122	1000	CERS5	ceramide synthase 5 [Source:HGNC Symbol;Acc:HGNC:23749]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K23727;K23727;K23727	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000139625	10.054	9.027	10.952	10.567	9.886	13.956	691.05	627.16	563.39	530.78	614.76	690.89	MAP3K12	mitogen-activated protein kinase kinase kinase 12 [Source:HGNC Symbol;Acc:HGNC:6851]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04423	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030426//growth cone	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0035556//intracellular signal transduction;GO:0043507//positive regulation of JUN kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000672//negative regulation of motor neuron apoptotic process"	--
ENSG00000139626	0.137	0.103	0.035	0.035	0.376	0.237	7	6	1	1	6.02	10	ITGB7	integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cancer: overview;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Immune system;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05202//Transcriptional misregulation in cancer;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko04672//Intestinal immune network for IgA production;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06590;K06590;K06590;K06590;K06590;K06590;K06590;K06590;K06590;K06590;K06590	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034669//integrin alpha4-beta7 complex;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0003366//cell-matrix adhesion involved in ameboidal cell migration;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043113//receptor clustering;GO:0046718//viral entry into host cell;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0072678//T cell migration	--
ENSG00000139629	5.31	5.638	5.585	6.601	7.932	5.921	336	326	264	318	359	332	GALNT6	polypeptide N-acetylgalactosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:4128]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing	--
ENSG00000139631	1.936	1.821	1.751	3.383	4.992	2.126	55	54	33	73	84	44	CSAD	cysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Metabolism of cofactors and vitamins;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00410//beta-Alanine metabolism;ko00770//Pantothenate and CoA biosynthesis;ko00430//Taurine and hypotaurine metabolism	K18966;K18966;K18966;K18966	GO:0005737//cytoplasm	GO:0003824//catalytic activity;GO:0004068//aspartate 1-decarboxylase activity;GO:0004782//sulfinoalanine decarboxylase activity;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding	GO:0019449//L-cysteine catabolic process to hypotaurine;GO:0019452//L-cysteine catabolic process to taurine;GO:0019752//carboxylic acid metabolic process;GO:0042412//taurine biosynthetic process	--
ENSG00000139636	3.612	6.454	4.603	4.515	5.844	6.129	142	204	142	118	171	137	LMBR1L	limb development membrane protein 1 like [Source:HGNC Symbol;Acc:HGNC:18268]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0030217//T cell differentiation;GO:0042098//T cell proliferation;GO:0060218//hematopoietic stem cell differentiation;GO:0070231//T cell apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000139637	27.462	30.51	30.319	35.165	33.38	35.025	681	758	557	648	698	628	MYG1	MYG1 exonuclease [Source:HGNC Symbol;Acc:HGNC:17590]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003674//molecular_function;GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0035641//locomotory exploration behavior;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000139641	19.635	20.349	20.693	19.356	19.24	17.816	1636	1737	1287	1180	1379	1107	ESYT1	extended synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:29534]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006869//lipid transport;GO:0061817//endoplasmic reticulum-plasma membrane tethering	--
ENSG00000139644	290.912	281.835	295.916	296.023	290.319	312.976	14193	14306	11398	11374	12758	11800	TMBIM6	transmembrane BAX inhibitor motif containing 6 [Source:HGNC Symbol;Acc:HGNC:11723]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K21889	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0060698//endoribonuclease inhibitor activity	GO:0002638//negative regulation of immunoglobulin production;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006986//response to unfolded protein;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0032091//negative regulation of protein binding;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0033119//negative regulation of RNA splicing;GO:0034620//cellular response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0060702//negative regulation of endoribonuclease activity;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1902065//response to L-glutamate;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000139645	22.57	22.488	25.559	24.877	26.051	25.608	4064	4070	3399	3318	3963	3355	ANKRD52	ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000139648	0.021	0	0	0	0	0	1	0	0	0	0	0	KRT71	keratin 71 [Source:HGNC Symbol;Acc:HGNC:28927]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0031069//hair follicle morphogenesis;GO:0045109//intermediate filament organization	--
ENSG00000139651	4.552	4.17	4.867	4.556	4.301	5.327	808	744	638	599	644.98	688	ZNF740	zinc finger protein 740 [Source:HGNC Symbol;Acc:HGNC:27465]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000139656	0.04	0.118	0	0	0.094	0	1	3	0	0	2	0	SMIM2	small integral membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:28776]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000139668	2.9	2.251	2.533	2.448	2.697	2.74	561	439	362	352	442	387	WDFY2	WD repeat and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20482]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0045600//positive regulation of fat cell differentiation	--
ENSG00000139675	3.292	3.308	3.591	2.39	3.367	3.144	91.7	92.62	73.89	49.31	79.25	63.73	HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1 like 2 [Source:HGNC Symbol;Acc:HGNC:27067]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12741;K12741	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0051028//mRNA transport	--
ENSG00000139679	0.073	0.024	0.033	0.264	0.087	0.067	3	1	1	8	3	2	LPAR6	lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway	K04273;K04273;K04273;K04273	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0070915//lysophosphatidic acid receptor activity	GO:0001835//blastocyst hatching;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000139684	62.097	60.377	53.98	56.74	54.64	53.418	1542	1495	981	1019	1134	964	ESD	esterase D [Source:HGNC Symbol;Acc:HGNC:3465]	-	-	-	-	GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0018738//S-formylglutathione hydrolase activity;GO:0042802//identical protein binding;GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity"	GO:0008150//biological_process;GO:0046294//formaldehyde catabolic process	--
ENSG00000139687	22.203	16.887	16.935	12.299	14.135	16.565	2170	1678	1237	901	1181	1175	RB1	RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05226//Gastric cancer;ko04110//Cell cycle;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05219//Bladder cancer	K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618;K06618	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005819//spindle;GO:0005829//cytosol;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0016514//SWI/SNF complex;GO:0016605//PML body;GO:0035189//Rb-E2F complex;GO:0043229//intracellular organelle;GO:0061793//chromatin lock complex	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0051219//phosphoprotein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061676//importin-alpha family protein binding;GO:0097718//disordered domain specific binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001558//regulation of cell growth;GO:0001894//tissue homeostasis;GO:0002062//chondrocyte differentiation;GO:0003180//aortic valve morphogenesis;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0007283//spermatogenesis;GO:0007346//regulation of mitotic cell cycle;GO:0008150//biological_process;GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030308//negative regulation of cell growth;GO:0031134//sister chromatid biorientation;GO:0031175//neuron projection development;GO:0031507//heterochromatin assembly;GO:0032869//cellular response to insulin stimulus;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0034349//glial cell apoptotic process;GO:0035914//skeletal muscle cell differentiation;GO:0042551//neuron maturation;GO:0043353//enucleate erythrocyte differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043550//regulation of lipid kinase activity;GO:0045445//myoblast differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045786//negative regulation of cell cycle;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0051146//striated muscle cell differentiation;GO:0051301//cell division;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0071459//protein localization to chromosome, centromeric region;GO:0071466//cellular response to xenobiotic stimulus;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0071922//regulation of cohesin loading;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0090230//regulation of centromere complex assembly;GO:0097284//hepatocyte apoptotic process;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1902948//negative regulation of tau-protein kinase activity;GO:1903055//positive regulation of extracellular matrix organization;GO:1903944//negative regulation of hepatocyte apoptotic process;GO:1904028//positive regulation of collagen fibril organization;GO:1904761//negative regulation of myofibroblast differentiation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000139697	3.263	2.579	2.799	1.708	2.285	2.697	753	595	477	292	444	452	SBNO1	strawberry notch homolog 1 [Source:HGNC Symbol;Acc:HGNC:22973]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0031490//chromatin DNA binding;GO:0042393//histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008150//biological_process"	--
ENSG00000139714	1.184	1.684	0.914	1.215	0.818	1.423	44	56	24	32	24	32	MORN3	MORN repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:29807]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000139718	4.778	5.134	5.26	5.127	5.495	5.351	848	916	681	674	824	691	SETD1B	"SET domain containing 1B, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:29187]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11422;K11422	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0035097//histone methyltransferase complex;GO:0048188//Set1C/COMPASS complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific)	GO:0006325//chromatin organization;GO:0032259//methylation;GO:0044648//histone H3-K4 dimethylation;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0097692//histone H3-K4 monomethylation	--
ENSG00000139719	10.54	8.079	9.734	8.246	8.304	9.054	626	596	506	429	492	435	VPS33A	VPS33A core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:18179]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20182	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005776//autophagosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030897//HOPS complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0033263//CORVET complex;GO:0048471//perinuclear region of cytoplasm;GO:0071439//clathrin complex	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030220//platelet formation;GO:0032400//melanosome localization;GO:0032418//lysosome localization;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly;GO:0035751//regulation of lysosomal lumen pH;GO:0048070//regulation of developmental pigmentation;GO:0097352//autophagosome maturation	--
ENSG00000139722	18.81	19.03	19.371	21.571	19.242	18.463	1046	1047	803	880	888	754	VPS37B	VPS37B subunit of ESCRT-I [Source:HGNC Symbol;Acc:HGNC:25754]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12185	GO:0000813//ESCRT I complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0043657//host cell;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	GO:0006612//protein targeting to membrane;GO:0006623//protein targeting to vacuole;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0019076//viral release from host cell;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046907//intracellular transport;GO:0075733//intracellular transport of virus;GO:1903774//positive regulation of viral budding via host ESCRT complex	--
ENSG00000139725	26.697	28.293	33.643	33.061	34.162	32.169	1196.84	1111.09	1026.22	1080.53	1234.98	977.56	RHOF	"ras homolog family member F, filopodia associated [Source:HGNC Symbol;Acc:HGNC:15703]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000139726	17.253	15.63	15.149	15.2	13.936	16.035	973	886	631	635	664	658	DENR	density regulated re-initiation and release factor [Source:HGNC Symbol;Acc:HGNC:2769]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0001731//formation of translation preinitiation complex;GO:0002188//translation reinitiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0032790//ribosome disassembly;GO:0075522//IRES-dependent viral translational initiation	--
ENSG00000139734	1.433	1.245	1.389	0.818	1.132	0.868	133	117	101	54	86	59	DIAPH3	diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05745	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003779//actin binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding	GO:0007010//cytoskeleton organization;GO:0016043//cellular component organization;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization	--
ENSG00000139737	13.272	11.323	11.264	9.647	12.007	14.086	480	441	304	287	357	404	SLAIN1	SLAIN motif family member 1 [Source:HGNC Symbol;Acc:HGNC:26387]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0035371//microtubule plus-end	GO:0005515//protein binding	GO:0007020//microtubule nucleation;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization	--
ENSG00000139746	9.948	6.775	6.908	6.359	6.934	8.106	835	575	413	385	487	488	RBM26	RNA binding motif protein 26 [Source:HGNC Symbol;Acc:HGNC:20327]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing	--
ENSG00000139767	1.327	1.144	1.247	1.637	1.455	1.32	232	201	161	212	215	168	SRRM4	serine/arginine repetitive matrix 4 [Source:HGNC Symbol;Acc:HGNC:29389]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0007605//sensory perception of sound;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0042551//neuron maturation;GO:0043484//regulation of RNA splicing"	--
ENSG00000139780	0.119	0.236	0.161	0.12	0.211	0.53	4	8	4	3	6	13	METTL21C	"methyltransferase 21C, AARS1 lysine [Source:HGNC Symbol;Acc:HGNC:33717]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding	GO:0006479//protein methylation;GO:0007519//skeletal muscle tissue development;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0018022//peptidyl-lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation;GO:0071549//cellular response to dexamethasone stimulus	--
ENSG00000139793	14.899	10.141	8.025	8.003	8.988	9.601	954	700	479	429	553	511	MBNL2	muscleblind like splicing regulator 2 [Source:HGNC Symbol;Acc:HGNC:16746]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing"	--
ENSG00000139797	0	0	0	0	0	0	0	0	0	0	0	0	RNF113B	ring finger protein 113B [Source:HGNC Symbol;Acc:HGNC:17267]	-	-	-	-	GO:0005684//U2-type spliceosomal complex	GO:0046872//metal ion binding	GO:0034247//snoRNA splicing	--
ENSG00000139800	0.064	0.032	0.087	0.058	0.051	0	6	3	6	4	4	0	ZIC5	Zic family member 5 [Source:HGNC Symbol;Acc:HGNC:20322]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0030154//cell differentiation	zf-C2H2
ENSG00000139826	7.74	5.904	6.463	5.439	5.832	6.947	853	654	526	444	543	557	ABHD13	abhydrolase domain containing 13 [Source:HGNC Symbol;Acc:HGNC:20293]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032839//dendrite cytoplasm	GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity	GO:0002084//protein depalmitoylation	--
ENSG00000139832	3.423	3.883	3.422	2.894	3.446	3.737	107	122	79	67	91	85	RAB20	"RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260]"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0071346//cellular response to interferon-gamma;GO:0090383//phagosome acidification;GO:0090385//phagosome-lysosome fusion	--
ENSG00000139835	3.06	3.37	3.596	3.358	3.087	5.083	95	106	73	78	76	108	GRTP1	growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGNC:20310]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000139842	26.049	24.666	24.975	21.102	21.241	25.616	1718	1490	1176	967	1124	1112	CUL4A	cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation;Replication and repair"	ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko03420//Nucleotide excision repair	K10609;K10609;K10609	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0001701//in utero embryonic development;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0030097//hemopoiesis;GO:0030853//negative regulation of granulocyte differentiation;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0034644//cellular response to UV;GO:0035019//somatic stem cell population maintenance;GO:0042254//ribosome biogenesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0048511//rhythmic process;GO:0051246//regulation of protein metabolic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000001//regulation of DNA damage checkpoint;GO:2000819//regulation of nucleotide-excision repair	--
ENSG00000139865	0	0	0	0	0.175	0	0	0	0	0	6	0	TTC6	tetratricopeptide repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:19739]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000139874	0.033	0	0	0.03	0.013	0	3	0	0	2	1	0	SSTR1	somatostatin receptor 1 [Source:HGNC Symbol;Acc:HGNC:11330]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K04217;K04217;K04217	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004994//somatostatin receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007215//glutamate receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0021549//cerebellum development;GO:0030900//forebrain development;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0071392//cellular response to estradiol stimulus;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000139880	1.907	2.369	2.42	3.813	2.827	4.054	128	158	127	181	171	213	CDH24	cadherin 24 [Source:HGNC Symbol;Acc:HGNC:14265]	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0008013//beta-catenin binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0070097//delta-catenin binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000139890	0.052	0.119	0.07	0.14	0.117	0.143	2	4	2	4	3	4	REM2	RRAD and GEM like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:20248]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005525//GTP binding	-	--
ENSG00000139899	0.448	0.291	0.671	0.578	0.673	0.161	23	15	18.04	22	23	6	CBLN3	cerebellin 3 precursor [Source:HGNC Symbol;Acc:HGNC:20146]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	GO:0099558//maintenance of synapse structure	--
ENSG00000139908	0.262	0.218	0.382	0.073	0.235	0.243	5	5	5	1	3	3	TSSK4	testis specific serine kinase 4 [Source:HGNC Symbol;Acc:HGNC:19825]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009566//fertilization;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0032793//positive regulation of CREB transcription factor activity;GO:0035556//intracellular signal transduction;GO:1990443//peptidyl-threonine autophosphorylation	--
ENSG00000139910	2.747	1.555	3.711	3.593	2.16	3.046	121	70	82	71	80	95	NOVA1	NOVA alternative splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:7886]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:1990825//sequence-specific mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0051252//regulation of RNA metabolic process;GO:0120163//negative regulation of cold-induced thermogenesis"	--
ENSG00000139914	0.489	0.238	0.467	0.196	0.083	0.2	15	7.33	7	5.44	2	4	FITM1	fat storage inducing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:33714]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003674//molecular_function;GO:0017129//triglyceride binding;GO:0019992//diacylglycerol binding	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0010890//positive regulation of sequestering of triglyceride;GO:0019915//lipid storage;GO:0034389//lipid droplet organization;GO:0140042//lipid droplet formation	--
ENSG00000139915	0.049	0.063	0.345	0.022	0	0	3	1	4	1	0	0	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2 [Source:HGNC Symbol;Acc:HGNC:19835]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0021522//spinal cord motor neuron differentiation	--
ENSG00000139921	13.432	12.771	11.813	12.073	10.27	14.262	889	880	593	555	588	648	TMX1	thioredoxin related transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:15487]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015036//disulfide oxidoreductase activity	GO:0034976//response to endoplasmic reticulum stress	--
ENSG00000139926	1.96	2.078	1.319	1.363	1.479	1.666	170	174	78	101	117	105	FRMD6	FERM domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19839]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16822;K16822	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043296//apical junction complex	GO:0005515//protein binding	GO:0003383//apical constriction;GO:0031032//actomyosin structure organization;GO:0032970//regulation of actin filament-based process;GO:0034613//cellular protein localization	--
ENSG00000139946	4.015	2.835	3.452	2.541	2.877	3.555	403	347	261	213	296	315	PELI2	pellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbol;Acc:HGNC:8828]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0001934//positive regulation of protein phosphorylation;GO:0008592//regulation of Toll signaling pathway;GO:0016567//protein ubiquitination;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000139970	0.76	0.84	0.578	0.141	0.424	0.15	39	44	23	7	17	6	RTN1	reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0030182//neuron differentiation;GO:1902430//negative regulation of amyloid-beta formation	--
ENSG00000139971	2.175	2.526	1.357	0.912	0.993	0.816	293	317	135	91	113	80	ARMH4	armadillo like helical domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19846]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000139973	0.187	0.055	0.108	0.02	0.037	0	24	16	12	1	9	0	SYT16	synaptotagmin 16 [Source:HGNC Symbol;Acc:HGNC:23142]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding	GO:0006887//exocytosis	--
ENSG00000139974	14.18	13.692	11.255	11.676	12.672	12.162	423	398	268	278	310	286	SLC38A6	solute carrier family 38 member 6 [Source:HGNC Symbol;Acc:HGNC:19863]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0006868//glutamine transport	--
ENSG00000139977	12.561	11.002	10.631	9.478	11.323	12.578	1191	1055	795	632	850	847	NAA30	"N-alpha-acetyltransferase 30, NatC catalytic subunit [Source:HGNC Symbol;Acc:HGNC:19844]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0031417//NatC complex	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0017196//N-terminal peptidyl-methionine acetylation	--
ENSG00000139985	0.239	0.238	0.33	0.199	0.162	0.2	14	14	16	9	9	8	ADAM21	ADAM metallopeptidase domain 21 [Source:HGNC Symbol;Acc:HGNC:200]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:1990913//sperm head plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007338//single fertilization;GO:0008584//male gonad development	--
ENSG00000139988	0.026	0	0	0.036	0	0	1	0	0	1	0	0	RDH12	retinol dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:19977]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11153;K11153	GO:0001917//photoreceptor inner segment;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0060342//photoreceptor inner segment membrane	GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0052650//NADP-retinol dehydrogenase activity;GO:0102354//11-cis-retinol dehydrogenase activity	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0007601//visual perception;GO:0042572//retinol metabolic process;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0110095//cellular detoxification of aldehyde	--
ENSG00000139990	16.233	15.375	14.875	14.331	16.408	16.06	1324	1298	919	858	1097	882	DCAF5	DDB1 and CUL4 associated factor 5 [Source:HGNC Symbol;Acc:HGNC:20224]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000139998	4.827	3.973	4.141	3.695	4.849	3.783	334	269	211	181	292	190	RAB15	"RAB15, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20150]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0032593//insulin-responsive compartment;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0032482//Rab protein signal transduction;GO:0032869//cellular response to insulin stimulus;GO:0072659//protein localization to plasma membrane;GO:1903307//positive regulation of regulated secretory pathway	--
ENSG00000140006	4.544	4.134	5.031	4.399	5.449	5.422	293	249	209	197	227	218	WDR89	WD repeat domain 89 [Source:HGNC Symbol;Acc:HGNC:20489]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000140009	0.232	0.126	0.054	0.029	0.147	0.288	25	16	4	3	16	18	ESR2	estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Endocrine system;Endocrine system	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko04915//Estrogen signaling pathway;ko01522//Endocrine resistance;ko04917//Prolactin signaling pathway;ko04929//GnRH secretion	K08551;K08551;K08551;K08551;K08551;K08551;K08551	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0030284//estrogen receptor activity;GO:0034056//estrogen response element binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0048019//receptor antagonist activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0014070//response to organic cyclic compound;GO:0030308//negative regulation of cell growth;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0033993//response to lipid;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0071392//cellular response to estradiol stimulus;GO:2000272//negative regulation of signaling receptor activity"	ESR-like
ENSG00000140015	0.479	0.599	0.831	0.618	0.664	0.615	112	102	97	65	82	88	KCNH5	potassium voltage-gated channel subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:6254]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005516//calmodulin binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000140022	6.91	5.654	5.411	3.861	4.188	4.441	1417	1208	794	566	730	667	STON2	stonin 2 [Source:HGNC Symbol;Acc:HGNC:30652]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006897//endocytosis;GO:0016192//vesicle-mediated transport;GO:0030100//regulation of endocytosis;GO:0036465//synaptic vesicle recycling;GO:0048488//synaptic vesicle endocytosis	--
ENSG00000140025	3.932	3.504	2.379	2.309	3.09	1.892	166	127	98	79	144	67	EFCAB11	EF-hand calcium binding domain 11 [Source:HGNC Symbol;Acc:HGNC:20357]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000140030	0	0	0	0	0	0	0	0	0	0	0	0	GPR65	G protein-coupled receptor 65 [Source:HGNC Symbol;Acc:HGNC:4517]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007275//multicellular organism development;GO:0010447//response to acidic pH;GO:0031532//actin cytoskeleton reorganization;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0090630//activation of GTPase activity	--
ENSG00000140043	9.456	8.58	10.188	8.176	9.662	10.642	505.67	436.18	401.6	312.73	438.91	415.55	PTGR2	prostaglandin reductase 2 [Source:HGNC Symbol;Acc:HGNC:20149]	-	-	-	-	GO:0005737//cytoplasm	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0036132//13-prostaglandin reductase activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity"	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process	--
ENSG00000140044	14.455	15.473	14.953	16.368	17.08	22.508	506	469	349	394	466	567	JDP2	Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:0042803//protein homodimerization activity;GO:0043522//leucine zipper domain binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0031063//regulation of histone deacetylation;GO:0031065//positive regulation of histone deacetylation;GO:0045599//negative regulation of fat cell differentiation"	TF_bZIP
ENSG00000140057	3.739	3.735	3.367	2.104	1.905	3.623	196	203	130	79	96	126	AK7	adenylate kinase 7 [Source:HGNC Symbol;Acc:HGNC:20091]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019205//nucleobase-containing compound kinase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000140067	0	0	0	0	0	0	0	0	0	0	0	0	FAM181A	family with sequence similarity 181 member A [Source:HGNC Symbol;Acc:HGNC:20491]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000140090	0	0.005	0	0	0	0	0	1	0	0	0	0	SLC24A4	solute carrier family 24 member 4 [Source:HGNC Symbol;Acc:HGNC:10978]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K13752	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0044214//spanning component of plasma membrane;GO:0120199//cone photoreceptor outer segment	"GO:0005262//calcium channel activity;GO:0005516//calmodulin binding;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity;GO:0048306//calcium-dependent protein binding"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007602//phototransduction;GO:0007608//sensory perception of smell;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009644//response to high light intensity;GO:0010469//regulation of signaling receptor activity;GO:0010628//positive regulation of gene expression;GO:0021630//olfactory nerve maturation;GO:0035725//sodium ion transmembrane transport;GO:0036368//cone photoresponse recovery;GO:0042756//drinking behavior;GO:0050849//negative regulation of calcium-mediated signaling;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0070166//enamel mineralization;GO:0070588//calcium ion transmembrane transport;GO:0071486//cellular response to high light intensity;GO:0071805//potassium ion transmembrane transport;GO:0086009//membrane repolarization;GO:0097186//amelogenesis;GO:0098656//anion transmembrane transport;GO:0098703//calcium ion import across plasma membrane;GO:1903998//regulation of eating behavior;GO:1990034//calcium ion export across plasma membrane;GO:1990680//response to melanocyte-stimulating hormone;GO:1990834//response to odorant	--
ENSG00000140092	73.186	79.976	76.813	66.129	74.794	63.557	3929	4323	3058	2644	3397	2478	FBLN5	fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071953//elastic fiber	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0042803//protein homodimerization activity	GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0034394//protein localization to cell surface;GO:0046903//secretion;GO:0048251//elastic fiber assembly;GO:2000121//regulation of removal of superoxide radicals	--
ENSG00000140093	0.165	0.029	0.026	0.092	0.023	0	17	3	2	7	2	0	SERPINA10	serpin family A member 10 [Source:HGNC Symbol;Acc:HGNC:15996]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0097421//liver regeneration	--
ENSG00000140104	5.368	4.955	5.084	5.222	5.605	4.71	240	239	182	172	211	154	CLBA1	clathrin binding box of aftiphilin containing 1 [Source:HGNC Symbol;Acc:HGNC:20126]	-	-	-	-	GO:0030121//AP-1 adaptor complex;GO:0032588//trans-Golgi network membrane	GO:0030276//clathrin binding	GO:0046907//intracellular transport	--
ENSG00000140105	52.854	59.785	66.439	61.104	53.139	83.704	2237	2330	1844	1694	1951	2319	WARS1	tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01867	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004830//tryptophan-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0019210//kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity	GO:0001525//angiogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0006469//negative regulation of protein kinase activity;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010835//regulation of protein ADP-ribosylation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0044238//primary metabolic process;GO:0045765//regulation of angiogenesis	--
ENSG00000140107	0	0	0	0	0	0	0	0	0	0	0	0	SLC25A47	solute carrier family 25 member 47 [Source:HGNC Symbol;Acc:HGNC:20115]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015227//acyl carnitine transmembrane transporter activity	GO:0006844//acyl carnitine transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:1902616//acyl carnitine transmembrane transport	--
ENSG00000140153	9.232	8.504	9.528	9.166	7.892	9.712	425	432	311	291	324	339	WDR20	WD repeat domain 20 [Source:HGNC Symbol;Acc:HGNC:19667]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000140157	23.948	20.432	20.217	23.179	21.609	25.371	1091.45	955.18	706.6	761.63	865.61	813.36	NIPA2	NIPA magnesium transporter 2 [Source:HGNC Symbol;Acc:HGNC:17044]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015095//magnesium ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015693//magnesium ion transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000140199	5.117	5.247	4.633	4.763	4.335	3.915	668.1	700.25	439.08	359	419	347	SLC12A6	solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0045202//synapse	GO:0008519//ammonium transmembrane transporter activity;GO:0015079//potassium ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity	GO:0001525//angiogenesis;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0007268//chemical synaptic transmission;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0071476//cellular hypotonic response;GO:0071477//cellular hypotonic salinity response;GO:0071805//potassium ion transmembrane transport;GO:0140157//ammonium import across plasma membrane;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000140254	0.062	0.026	0	0.278	0.269	0.197	4	1	0	10	7	8	DUOXA1	dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031252//cell leading edge	GO:0019899//enzyme binding	GO:0008104//protein localization;GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:0015031//protein transport;GO:0034613//cellular protein localization;GO:0042743//hydrogen peroxide metabolic process;GO:0045666//positive regulation of neuron differentiation;GO:0050727//regulation of inflammatory response;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000609//regulation of thyroid hormone generation	--
ENSG00000140259	21.097	20.003	17.414	13.317	15.307	14.692	894	852	545	418	548	453	MFAP1	microfibril associated protein 1 [Source:HGNC Symbol;Acc:HGNC:7032]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005813//centrosome;GO:0071005//U2-type precatalytic spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000140262	14.774	22.104	12.688	9.24	10.592	12.429	1369	1156	817	598	781	741	TCF12	transcription factor 12 [Source:HGNC Symbol;Acc:HGNC:11623]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:0043425//bHLH transcription factor binding;GO:0046332//SMAD binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0071837//HMG box domain binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006955//immune response;GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000140263	8.344	8.695	8.602	8.52	7.614	8.872	595	569	422	474	486	396	SORD	sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00040//Pentose and glucuronate interconversions;ko00051//Fructose and mannose metabolism	K00008;K00008;K00008	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005929//cilium;GO:0016020//membrane;GO:0031514//motile cilium;GO:0031966//mitochondrial membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	"GO:0000721//(R,R)-butanediol dehydrogenase activity;GO:0003939//L-iditol 2-dehydrogenase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0046526//D-xylulose reductase activity;GO:0046872//metal ion binding;GO:0050255//ribitol 2-dehydrogenase activity;GO:0051287//NAD binding"	GO:0006006//glucose metabolic process;GO:0006060//sorbitol metabolic process;GO:0006062//sorbitol catabolic process;GO:0006970//response to osmotic stress;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0030317//flagellated sperm motility;GO:0031667//response to nutrient levels;GO:0046370//fructose biosynthetic process;GO:0046686//response to cadmium ion;GO:0046688//response to copper ion;GO:0051160//L-xylitol catabolic process;GO:0051164//L-xylitol metabolic process	--
ENSG00000140264	174.609	191.302	206.296	224.342	190.923	193.673	4300.38	4642.81	3762.13	4088.26	4068.57	3486.84	SERF2	small EDRK-rich factor 2 [Source:HGNC Symbol;Acc:HGNC:10757]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0003674//molecular_function	GO:0031648//protein destabilization	--
ENSG00000140265	3.002	2.479	2.429	2.247	2.099	2.685	332	297	214	189	200	213	ZSCAN29	zinc finger and SCAN domain containing 29 [Source:HGNC Symbol;Acc:HGNC:26673]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000140274	0	0	0	0	0	0	0	0	0	0	0	0	DUOXA2	dual oxidase maturation factor 2 [Source:HGNC Symbol;Acc:HGNC:32698]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K17232	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0045177//apical part of cell	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0008104//protein localization;GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:0015031//protein transport;GO:0034613//cellular protein localization;GO:0042743//hydrogen peroxide metabolic process;GO:0050727//regulation of inflammatory response;GO:0051604//protein maturation;GO:2000147//positive regulation of cell motility;GO:2000609//regulation of thyroid hormone generation	--
ENSG00000140279	0.03	0.038	0.01	0.01	0.072	0.094	4	5	1	1	8	9	DUOX2	dual oxidase 2 [Source:HGNC Symbol;Acc:HGNC:13273]	Organismal Systems;Environmental Information Processing;Organismal Systems	Endocrine system;Signal transduction;Immune system	ko04918//Thyroid hormone synthesis;ko04013//MAPK signaling pathway - fly;ko04624//Toll and Imd signaling pathway	K13411;K13411;K13411	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0043020//NADPH oxidase complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0106293//NADH oxidase H202-forming activity;GO:0106294//NADPH oxidase H202-forming activity	GO:0006590//thyroid hormone generation;GO:0006952//defense response;GO:0006979//response to oxidative stress;GO:0009566//fertilization;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030282//bone mineralization;GO:0030878//thyroid gland development;GO:0035264//multicellular organism growth;GO:0042335//cuticle development;GO:0042403//thyroid hormone metabolic process;GO:0042445//hormone metabolic process;GO:0042446//hormone biosynthetic process;GO:0042554//superoxide anion generation;GO:0042744//hydrogen peroxide catabolic process;GO:0048839//inner ear development;GO:0048855//adenohypophysis morphogenesis;GO:0050665//hydrogen peroxide biosynthetic process;GO:0051591//response to cAMP;GO:0072593//reactive oxygen species metabolic process;GO:0090303//positive regulation of wound healing;GO:0098869//cellular oxidant detoxification;GO:2000147//positive regulation of cell motility	--
ENSG00000140280	1.019	1.698	1.623	1.427	1.251	1.609	27	44	28	28	28	31	LYSMD2	LysM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28571]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000140284	5.541	5.774	5.761	4.942	4.165	4.669	274	287	210	181	174	168	SLC27A2	solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996]	Human Diseases;Cellular Processes;Organismal Systems	Endocrine and metabolic disease;Transport and catabolism;Endocrine system	ko04931//Insulin resistance;ko04146//Peroxisome;ko03320//PPAR signaling pathway	K08746;K08746;K08746	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005524//ATP binding;GO:0015245//fatty acid transmembrane transporter activity;GO:0016874//ligase activity;GO:0019899//enzyme binding;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0047747//cholate-CoA ligase activity;GO:0050197//phytanate-CoA ligase activity;GO:0070251//pristanate-CoA ligase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001561//fatty acid alpha-oxidation;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006699//bile acid biosynthetic process;GO:0015908//fatty acid transport;GO:0042760//very long-chain fatty acid catabolic process;GO:0044539//long-chain fatty acid import into cell;GO:0097089//methyl-branched fatty acid metabolic process	--
ENSG00000140285	2.195	2.28	1.325	2.645	1.793	2.965	187.14	144	108	77	88	108	FGF7	fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0005104//fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity	"GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008544//epidermis development;GO:0009611//response to wounding;GO:0009887//animal organ morphogenesis;GO:0010463//mesenchymal cell proliferation;GO:0010628//positive regulation of gene expression;GO:0010838//positive regulation of keratinocyte proliferation;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0031069//hair follicle morphogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0034394//protein localization to cell surface;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0051549//positive regulation of keratinocyte migration;GO:0051781//positive regulation of cell division;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0061033//secretion by lung epithelial cell involved in lung growth"	--
ENSG00000140287	0	0	0	0.03	0.026	0	0	0	0	1	1	0	HDC	histidine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4855]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K01590;K01590	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004398//histidine decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding	GO:0001694//histamine biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0006547//histidine metabolic process;GO:0006548//histidine catabolic process;GO:0019752//carboxylic acid metabolic process;GO:0042423//catecholamine biosynthetic process	--
ENSG00000140297	0.072	0	0	0.055	0	0	1	0	0	2	0	0	GCNT3	"glucosaminyl (N-acetyl) transferase 3, mucin type [Source:HGNC Symbol;Acc:HGNC:4205]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K09662;K09662	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047225//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0106325//acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0106326//acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0048729//tissue morphogenesis;GO:0050892//intestinal absorption;GO:0060993//kidney morphogenesis	--
ENSG00000140299	16.347	14.838	13.804	13.833	13.951	15.331	1067	844	620	554	692	626	BNIP2	BCL2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1083]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0050790//regulation of catalytic activity;GO:0090649//response to oxygen-glucose deprivation	--
ENSG00000140307	23.689	26.808	22.818	27.358	19.17	28.79	535	518	378	408	382	448	GTF2A2	general transcription factor IIA subunit 2 [Source:HGNC Symbol;Acc:HGNC:4647]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors	K03123;K03123	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005672//transcription factor TFIIA complex;GO:0030054//cell junction	GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000140319	275.954	278.744	259.575	204.613	197.825	200.996	5410	5803	3832	3060	3510	3240	SRP14	signal recognition particle 14 [Source:HGNC Symbol;Acc:HGNC:11299]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03104	"GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0048500//signal recognition particle;GO:1904813//ficolin-1-rich granule lumen"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008312//7S RNA binding;GO:0030942//endoplasmic reticulum signal peptide binding	GO:0006613//cotranslational protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0045047//protein targeting to ER	--
ENSG00000140320	8.11	7.65	8.427	9.413	9.469	9.941	777	739	600	671	767	695	BAHD1	bromo adjacent homology domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29153]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005694//chromosome	GO:0003682//chromatin binding;GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0031507//heterochromatin assembly;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000140323	0.034	0.008	0.026	0.098	0.131	0.063	9	2	5	19	29	12	DISP2	dispatched RND transporter family member 2 [Source:HGNC Symbol;Acc:HGNC:19712]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0007224//smoothened signaling pathway	--
ENSG00000140326	6.456	6.626	8.107	8.323	7.563	9.378	579	607	519	572	592	594	CDAN1	codanin 1 [Source:HGNC Symbol;Acc:HGNC:1713]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006325//chromatin organization;GO:0008104//protein localization;GO:0008156//negative regulation of DNA replication;GO:0031497//chromatin assembly	--
ENSG00000140332	13.965	15.982	15.58	10.051	12.819	13.555	1088	1241	852	619	819	728	TLE3	"TLE family member 3, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11839]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:1990907//beta-catenin-TCF complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0009887//animal organ morphogenesis;GO:0016055//Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis"	--
ENSG00000140350	71.692	65.376	65.007	56.923	66.405	61.577	1764	1790	1190	1137	1477	1194	ANP32A	acidic nuclear phosphoprotein 32 family member A [Source:HGNC Symbol;Acc:HGNC:13233]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006913//nucleocytoplasmic transport;GO:0035556//intracellular signal transduction;GO:0042981//regulation of apoptotic process	--
ENSG00000140365	24.552	24.375	25.357	27.846	25.938	27.325	431	444	335	371	400	346	COMMD4	COMM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26027]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000140367	11.588	9.79	10.382	8.518	9.276	9.722	683	585	466	387	459	393	UBE2Q2	ubiquitin conjugating enzyme E2 Q2 [Source:HGNC Symbol;Acc:HGNC:19248]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10582	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000140368	0.079	0.127	0.233	0	0.068	0.119	1	2	3	0	2	1	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9580]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12804	GO:0001931//uropod;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051015//actin filament binding	GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030041//actin filament polymerization;GO:0045087//innate immune response	--
ENSG00000140374	38.564	36.841	32.947	27.679	28.077	31.341	890	890	584	537	584	571	ETFA	electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045251//electron transfer flavoprotein complex	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0009063//cellular amino acid catabolic process;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase	--
ENSG00000140379	0	0	0	0	0	0	0	0	0	0	0	0	BCL2A1	BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Cell growth and death;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04064//NF-kappa B signaling pathway;ko04210//Apoptosis;ko05221//Acute myeloid leukemia	K02162;K02162;K02162;K02162	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006915//apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000140382	16.405	12.571	14.344	11.443	13.072	13.265	1043	905	646	645	850	772	HMG20A	high mobility group 20A [Source:HGNC Symbol;Acc:HGNC:5001]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0033234//negative regulation of protein sumoylation;GO:0045665//negative regulation of neuron differentiation"	HMG
ENSG00000140386	3.337	3.903	2.13	1.859	2.926	3.126	273	293	154	113	206	180	SCAPER	S-phase cyclin A associated protein in the ER [Source:HGNC Symbol;Acc:HGNC:13081]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:1990917//ooplasm	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001541//ovarian follicle development;GO:0001547//antral ovarian follicle growth;GO:0007283//spermatogenesis;GO:0060041//retina development in camera-type eye;GO:0072520//seminiferous tubule development	--
ENSG00000140391	237.999	242.719	244.06	245.956	230.562	250	8612	8907	6493	6549	7067	6539	TSPAN3	tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000140395	27.376	25.135	27.175	22.985	25.223	25.432	650	579	501	423	477	453	WDR61	WD repeat domain 61 [Source:HGNC Symbol;Acc:HGNC:30300]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12602	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016593//Cdc73/Paf1 complex;GO:0035327//transcriptionally active chromatin;GO:0055087//Ski complex	GO:0005515//protein binding	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0045638//negative regulation of myeloid cell differentiation;GO:0051568//histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:2001162//positive regulation of histone H3-K79 methylation	--
ENSG00000140396	8.338	7.342	7.367	5.536	7.61	8.134	1411	1135	876	695	903	935	NCOA2	nuclear receptor coactivator 2 [Source:HGNC Symbol;Acc:HGNC:7669]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko04915//Estrogen signaling pathway;ko04919//Thyroid hormone signaling pathway	K11255;K11255	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0019904//protein domain specific binding;GO:0030374//nuclear receptor coactivator activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007623//circadian rhythm;GO:0010468//regulation of gene expression;GO:0010906//regulation of glucose metabolic process;GO:0032570//response to progesterone;GO:0032870//cellular response to hormone stimulus;GO:0032922//circadian regulation of gene expression;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045475//locomotor rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:1900076//regulation of cellular response to insulin stimulus;GO:1904017//cellular response to Thyroglobulin triiodothyronine;GO:1904179//positive regulation of adipose tissue development"	--
ENSG00000140398	2.02	3.124	2.597	1.638	3.804	2.123	48.06	71	52.03	42.03	75.03	51	NEIL1	nei like DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:18448]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10567	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	"GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016829//lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity"	"GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006287//base-excision repair, gap-filling;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0008152//metabolic process;GO:0032074//negative regulation of nuclease activity;GO:0045008//depyrimidination"	--
ENSG00000140400	12.991	15.349	16.109	16.24	18.182	15.97	831.94	934	763.97	769.97	976.97	692	MAN2C1	mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]	Metabolism	Glycan biosynthesis and metabolism	ko00511//Other glycan degradation	K01191	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process	--
ENSG00000140403	1.993	1.414	1.966	2.616	1.611	2.26	123	83	85	111	88	101	DNAJA4	DnaJ heat shock protein family (Hsp40) member A4 [Source:HGNC Symbol;Acc:HGNC:14885]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0009408//response to heat;GO:0010596//negative regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0042026//protein refolding;GO:0090084//negative regulation of inclusion body assembly	--
ENSG00000140406	3.557	3.588	4.105	3.745	4.667	3.731	359	364	306	280	398	274	TLNRD1	talin rod domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13519]	-	-	-	-	GO:0001725//stress fiber	GO:0003779//actin binding;GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000140416	194.408	205.485	164.963	167.286	162.591	153.887	6349	6694	4004	4247	4650	3843	TPM1	tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko05206//MicroRNAs in cancer;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K10373;K10373;K10373;K10373;K10373	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005862//muscle thin filament tropomyosin;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030017//sarcomere;GO:0032059//bleb;GO:0032587//ruffle membrane	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding	GO:0003065//positive regulation of heart rate by epinephrine;GO:0006936//muscle contraction;GO:0006937//regulation of muscle contraction;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0008016//regulation of heart contraction;GO:0008360//regulation of cell shape;GO:0030049//muscle filament sliding;GO:0030336//negative regulation of cell migration;GO:0031529//ruffle organization;GO:0032781//positive regulation of ATPase activity;GO:0034614//cellular response to reactive oxygen species;GO:0042060//wound healing;GO:0045214//sarcomere organization;GO:0045785//positive regulation of cell adhesion;GO:0051496//positive regulation of stress fiber assembly;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration	--
ENSG00000140443	10.006	9.362	12.135	9.149	15.148	11.694	2526	2388	1850	1689	2365	1935	IGF1R	insulin like growth factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:5465]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Cancer: overview;Transport and catabolism;Signal transduction;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: specific types;Signal transduction;Transport and catabolism;Cancer: specific types;Cellular community - eukaryotes;Cell growth and death;Signal transduction;Signal transduction;Signal transduction;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Aging;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Aging;Nervous system;Endocrine system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05224//Breast cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko04520//Adherens junction;ko04213//Longevity regulating pathway - multiple species;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis	K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087;K05087	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005899//insulin receptor complex;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0030424//axon;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:1902911//protein kinase complex	GO:0000166//nucleotide binding;GO:0001965//G-protein alpha-subunit binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005009//insulin-activated receptor activity;GO:0005010//insulin-like growth factor-activated receptor activity;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031994//insulin-like growth factor I binding;GO:0042802//identical protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043559//insulin binding;GO:0043560//insulin receptor substrate binding;GO:0044877//protein-containing complex binding;GO:0140318//protein transporter activity	GO:0003230//cardiac atrium development;GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007409//axonogenesis;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021549//cerebellum development;GO:0021766//hippocampus development;GO:0030010//establishment of cell polarity;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0031667//response to nutrient levels;GO:0032467//positive regulation of cytokinesis;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0033197//response to vitamin E;GO:0033674//positive regulation of kinase activity;GO:0033690//positive regulation of osteoblast proliferation;GO:0035094//response to nicotine;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042593//glucose homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043243//positive regulation of protein-containing complex disassembly;GO:0043409//negative regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0044849//estrous cycle;GO:0045056//transcytosis;GO:0045471//response to ethanol;GO:0046328//regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048680//positive regulation of axon regeneration;GO:0051054//positive regulation of DNA metabolic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0071260//cellular response to mechanical stimulus;GO:0071333//cellular response to glucose stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071393//cellular response to progesterone stimulus;GO:0071394//cellular response to testosterone stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0090398//cellular senescence;GO:0097062//dendritic spine maintenance;GO:0097242//amyloid-beta clearance;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902065//response to L-glutamate;GO:1903944//negative regulation of hepatocyte apoptotic process;GO:1904045//cellular response to aldosterone;GO:1904193//negative regulation of cholangiocyte apoptotic process;GO:1904385//cellular response to angiotensin;GO:1904646//cellular response to amyloid-beta;GO:1990314//cellular response to insulin-like growth factor stimulus	--
ENSG00000140450	6.931	7.439	6.557	4.535	4.467	3.556	584	630	408	283	318	218	ARRDC4	arrestin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28087]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0140112//extracellular vesicle biogenesis	--
ENSG00000140451	0	0.042	0.029	0.171	0	0.087	0	2	1	6	0	3	PIF1	PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005739//mitochondrion"	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0010521//telomerase inhibitor activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity;GO:0033678//5'-3' DNA/RNA helicase activity;GO:0042162//telomeric DNA binding;GO:0043139//5'-3' DNA helicase activity;GO:0051880//G-quadruplex DNA binding	GO:0000002//mitochondrial genome maintenance;GO:0000723//telomere maintenance;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007004//telomere maintenance via telomerase;GO:0032204//regulation of telomere maintenance;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032508//DNA duplex unwinding;GO:0051974//negative regulation of telomerase activity	--
ENSG00000140455	8.241	6.479	6.671	6.044	7.748	6.753	463	399	269	244	357	307	USP3	ubiquitin specific peptidase 3 [Source:HGNC Symbol;Acc:HGNC:12626]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0090543//Flemming body	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability	--
ENSG00000140459	0.12	0	0	0	0.059	0	5	0	0	0	1	0	CYP11A1	cytochrome P450 family 11 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2590]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Endocrine system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K00498;K00498;K00498;K00498;K00498;K00498	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008386//cholesterol monooxygenase (side-chain-cleaving) activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0016125//sterol metabolic process;GO:0034650//cortisol metabolic process;GO:0042359//vitamin D metabolic process;GO:0071375//cellular response to peptide hormone stimulus	--
ENSG00000140463	6.988	7.74	6.842	8.545	6.043	7.971	346	338	216	196	234	214	BBS4	Bardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969]	-	-	-	-	GO:0000242//pericentriolar material;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0034451//centriolar satellite;GO:0034464//BBSome;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0034452//dynactin binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000226//microtubule cytoskeleton organization;GO:0000281//mitotic cytokinesis;GO:0001764//neuron migration;GO:0001843//neural tube closure;GO:0001895//retina homeostasis;GO:0001947//heart looping;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0007098//centrosome cycle;GO:0007286//spermatid development;GO:0007601//visual perception;GO:0007608//sensory perception of smell;GO:0008104//protein localization;GO:0010629//negative regulation of gene expression;GO:0015031//protein transport;GO:0016358//dendrite development;GO:0019216//regulation of lipid metabolic process;GO:0021591//ventricular system development;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030030//cell projection organization;GO:0030534//adult behavior;GO:0030837//negative regulation of actin filament polymerization;GO:0032402//melanosome transport;GO:0032465//regulation of cytokinesis;GO:0033210//leptin-mediated signaling pathway;GO:0033365//protein localization to organelle;GO:0034260//negative regulation of GTPase activity;GO:0034454//microtubule anchoring at centrosome;GO:0035176//social behavior;GO:0035845//photoreceptor cell outer segment organization;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0044321//response to leptin;GO:0045444//fat cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0045724//positive regulation of cilium assembly;GO:0046548//retinal rod cell development;GO:0046907//intracellular transport;GO:0048854//brain morphogenesis;GO:0050893//sensory processing;GO:0050896//response to stimulus;GO:0051457//maintenance of protein location in nucleus;GO:0051492//regulation of stress fiber assembly;GO:0060271//cilium assembly;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0060324//face development;GO:0060613//fat pad development;GO:0061512//protein localization to cilium;GO:0071539//protein localization to centrosome;GO:1902855//regulation of non-motile cilium assembly;GO:1903546//protein localization to photoreceptor outer segment;GO:1905515//non-motile cilium assembly	--
ENSG00000140464	8.56	9.33	11.485	10.405	10.149	8.674	584	659	520	557	614	440	PML	PML nuclear body scaffold [Source:HGNC Symbol;Acc:HGNC:9113]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases	"Infectious disease: viral;Cancer: overview;Cancer: overview;Transport and catabolism;Infectious disease: viral;Folding, sorting and degradation;Cancer: specific types"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04144//Endocytosis;ko05164//Influenza A;ko04120//Ubiquitin mediated proteolysis;ko05221//Acute myeloid leukemia	K10054;K10054;K10054;K10054;K10054;K10054;K10054	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:0031901//early endosome membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane"	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0032183//SUMO binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0050897//cobalt ion binding;GO:0140037//sumo-dependent protein binding	"GO:0001666//response to hypoxia;GO:0001932//regulation of protein phosphorylation;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006605//protein targeting;GO:0006606//protein import into nucleus;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007182//common-partner SMAD protein phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0009411//response to UV;GO:0010332//response to gamma radiation;GO:0010522//regulation of calcium ion transport into cytosol;GO:0010761//fibroblast migration;GO:0016525//negative regulation of angiogenesis;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0030099//myeloid cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030308//negative regulation of cell growth;GO:0030578//PML body organization;GO:0031065//positive regulation of histone deacetylation;GO:0032206//positive regulation of telomere maintenance;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032692//negative regulation of interleukin-1 production;GO:0032922//circadian regulation of gene expression;GO:0032938//negative regulation of translation in response to oxidative stress;GO:0034097//response to cytokine;GO:0042752//regulation of circadian rhythm;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045165//cell fate commitment;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048146//positive regulation of fibroblast proliferation;GO:0048384//retinoic acid receptor signaling pathway;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0051457//maintenance of protein location in nucleus;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0051974//negative regulation of telomerase activity;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0065003//protein-containing complex assembly;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071353//cellular response to interleukin-4;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0090398//cellular senescence;GO:0090402//oncogene-induced cell senescence;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1904816//positive regulation of protein localization to chromosome, telomeric region;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000758//positive regulation of peptidyl-lysine acetylation;GO:2000779//regulation of double-strand break repair;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000140465	0	0	0	0.031	0	0.063	0	0	0	1	0	2	CYP1A1	cytochrome P450 family 1 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2595]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Cancer: overview;Cardiovascular disease;Cancer: overview;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Lipid metabolism;Endocrine system;Amino acid metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis;ko00380//Tryptophan metabolism	K07408;K07408;K07408;K07408;K07408;K07408;K07408;K07408;K07408;K07408	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0003824//catalytic activity;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016679//oxidoreductase activity, acting on diphenols and related substances as donors;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016711//flavonoid 3'-monooxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016829//lyase activity;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0030544//Hsp70 protein binding;GO:0032451//demethylase activity;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:0070330//aromatase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0101021//estrogen 2-hydroxylase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity;GO:0120319//long-chain fatty acid omega-1 hydroxylase activity"	GO:0001666//response to hypoxia;GO:0001676//long-chain fatty acid metabolic process;GO:0001889//liver development;GO:0002933//lipid hydroxylation;GO:0006306//DNA methylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006778//porphyrin-containing compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007568//aging;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0008283//cell population proliferation;GO:0009308//amine metabolic process;GO:0009404//toxin metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009615//response to virus;GO:0009624//response to nematode;GO:0009635//response to herbicide;GO:0009636//response to toxic substance;GO:0009692//ethylene metabolic process;GO:0009804//coumarin metabolic process;GO:0009812//flavonoid metabolic process;GO:0010033//response to organic substance;GO:0010041//response to iron(III) ion;GO:0014070//response to organic cyclic compound;GO:0017143//insecticide metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0019341//dibenzo-p-dioxin catabolic process;GO:0019373//epoxygenase P450 pathway;GO:0032094//response to food;GO:0032496//response to lipopolysaccharide;GO:0032502//developmental process;GO:0033189//response to vitamin A;GO:0035902//response to immobilization stress;GO:0042359//vitamin D metabolic process;GO:0042572//retinol metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0043010//camera-type eye development;GO:0046483//heterocycle metabolic process;GO:0046677//response to antibiotic;GO:0046685//response to arsenic-containing substance;GO:0048565//digestive tract development;GO:0050665//hydrogen peroxide biosynthetic process;GO:0055093//response to hyperoxia;GO:0060137//maternal process involved in parturition;GO:0070365//hepatocyte differentiation;GO:0070988//demethylation;GO:0071280//cellular response to copper ion;GO:0071407//cellular response to organic cyclic compound;GO:0097267//omega-hydroxylase P450 pathway;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000140470	0.091	0.091	0.1	0.174	0.16	0.222	12	12	7	7	17	12	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif 17 [Source:HGNC Symbol;Acc:HGNC:17109]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization	--
ENSG00000140471	4.23	2.992	3.964	3.468	2.603	2.356	153	148	105	130	105	105	LINS1	lines homolog 1 [Source:HGNC Symbol;Acc:HGNC:30922]	-	-	-	-	-	-	GO:0050890//cognition	--
ENSG00000140474	6.603	6.134	9.737	7.189	6.572	8.919	301	297	291	246	260	270	ULK3	unc-51 like kinase 3 [Source:HGNC Symbol;Acc:HGNC:19703]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0007224//smoothened signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045880//positive regulation of smoothened signaling pathway;GO:0046777//protein autophosphorylation;GO:0072537//fibroblast activation;GO:0090398//cellular senescence;GO:1905037//autophagosome organization	--
ENSG00000140478	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6D	golgin A6 family member D [Source:HGNC Symbol;Acc:HGNC:32204]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	-	GO:0007030//Golgi organization	--
ENSG00000140479	4.738	5.26	3.858	2.325	3.442	2.786	413	464	251	153	206	134	PCSK6	proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0048406//nerve growth factor binding	"GO:0006508//proteolysis;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0007368//determination of left/right symmetry;GO:0009100//glycoprotein metabolic process;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0030510//regulation of BMP signaling pathway;GO:0032902//nerve growth factor production;GO:0032940//secretion by cell;GO:0051004//regulation of lipoprotein lipase activity"	--
ENSG00000140481	1.185	0.58	0.466	1.27	1.278	1.01	32	18	10	35	39	24	CCDC33	coiled-coil domain containing 33 [Source:HGNC Symbol;Acc:HGNC:26552]	-	-	-	-	GO:0005777//peroxisome	GO:0005515//protein binding	-	--
ENSG00000140488	0.465	0.471	0.531	0.429	0.629	0.286	28.2	27.82	16.82	20.28	26.19	13.49	CELF6	CUGBP Elav-like family member 6 [Source:HGNC Symbol;Acc:HGNC:14059]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing"	--
ENSG00000140497	34.439	37.056	36.115	40.947	39.6	38.328	1584	1608	1209	1436	1568	1345	SCAMP2	secretory carrier membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:10564]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport	--
ENSG00000140505	0	0	0	0	0	0	0	0	0	0	0	0	CYP1A2	cytochrome P450 family 1 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:2596]	Metabolism;Human Diseases;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Amino acid metabolism;Lipid metabolism;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00380//Tryptophan metabolism;ko00591//Linoleic acid metabolism;ko00232//Caffeine metabolism	K07409;K07409;K07409;K07409;K07409;K07409;K07409;K07409;K07409;K07409;K07409	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016829//lyase activity;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0032451//demethylase activity;GO:0034875//caffeine oxidase activity;GO:0046872//metal ion binding;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0101021//estrogen 2-hydroxylase activity;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006706//steroid catabolic process;GO:0006725//cellular aromatic compound metabolic process;GO:0006778//porphyrin-containing compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008210//estrogen metabolic process;GO:0009403//toxin biosynthetic process;GO:0009404//toxin metabolic process;GO:0009791//post-embryonic development;GO:0009820//alkaloid metabolic process;GO:0010468//regulation of gene expression;GO:0016098//monoterpenoid metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0022900//electron transport chain;GO:0030324//lung development;GO:0032259//methylation;GO:0032787//monocarboxylic acid metabolic process;GO:0042178//xenobiotic catabolic process;GO:0042572//retinol metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0045333//cellular respiration;GO:0046222//aflatoxin metabolic process;GO:0046483//heterocycle metabolic process;GO:0050665//hydrogen peroxide biosynthetic process;GO:0070989//oxidative demethylation;GO:0071276//cellular response to cadmium ion;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000140506	0	0	0	0	0	0	0	0	0	0	0	0	LMAN1L	"lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10081	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005537//mannose binding;GO:0030246//carbohydrate binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization	--
ENSG00000140511	4.115	4.317	3.546	8.059	8.283	5.963	168	162	83	238	290	177	HAPLN3	hyaluronan and proteoglycan link protein 3 [Source:HGNC Symbol;Acc:HGNC:21446]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005540//hyaluronic acid binding	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0043627//response to estrogen	--
ENSG00000140519	0.928	1.278	0.97	1.512	1.056	1.899	37	52	29	45	36	53	RHCG	Rh family C glycoprotein [Source:HGNC Symbol;Acc:HGNC:18140]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity;GO:0030506//ankyrin binding;GO:0042802//identical protein binding	GO:0006873//cellular ion homeostasis;GO:0006885//regulation of pH;GO:0015696//ammonium transport;GO:0015837//amine transport;GO:0030855//epithelial cell differentiation;GO:0042592//homeostatic process;GO:0070634//transepithelial ammonium transport;GO:0072488//ammonium transmembrane transport	--
ENSG00000140521	12.54	11.097	14.161	10.454	10.941	14.511	1064.64	1021.44	866.63	661.95	841.56	822.42	POLG	"DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]"	-	-	-	-	GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005760//gamma DNA polymerase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0042645//mitochondrial nucleoid	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003824//catalytic activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	"GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006287//base-excision repair, gap-filling;GO:0034645//cellular macromolecule biosynthetic process;GO:0043170//macromolecule metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0071897//DNA biosynthetic process;GO:0090304//nucleic acid metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000140522	290.415	285.723	366.212	425.966	376.014	431.183	9235	9063	8627	9980	10236	10045	RLBP1	retinaldehyde binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10024]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0044297//cell body	GO:0005502//11-cis retinal binding;GO:0005515//protein binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:1902936//phosphatidylinositol bisphosphate binding	GO:0006776//vitamin A metabolic process;GO:0007601//visual perception;GO:0050896//response to stimulus	--
ENSG00000140525	5.323	3.33	3.192	1.891	2.981	4.467	353.36	292.56	223.37	131.05	180.44	190.58	FANCI	FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10895	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:1990391//DNA repair complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0070182//DNA polymerase binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031398//positive regulation of protein ubiquitination;GO:0036297//interstrand cross-link repair	--
ENSG00000140526	85.615	85.248	95.583	105.701	106.166	105.964	14344	14370.24	12001	13250	15350.8	13171.54	ABHD2	"abhydrolase domain containing 2, acylglycerol lipase [Source:HGNC Symbol;Acc:HGNC:18717]"	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097524//sperm plasma membrane	GO:0003707//steroid hormone receptor activity;GO:0004806//triglyceride lipase activity;GO:0008126//acetylesterase activity;GO:0016787//hydrolase activity;GO:0033878//hormone-sensitive lipase activity;GO:0034338//short-chain carboxylesterase activity;GO:0042562//hormone binding;GO:0047372//acylglycerol lipase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0007340//acrosome reaction;GO:0009611//response to wounding;GO:0016042//lipid catabolic process;GO:0030336//negative regulation of cell migration;GO:0032570//response to progesterone;GO:0043401//steroid hormone mediated signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0046464//acylglycerol catabolic process;GO:0048240//sperm capacitation;GO:0051792//medium-chain fatty acid biosynthetic process;GO:0051793//medium-chain fatty acid catabolic process	--
ENSG00000140527	0.302	0.146	0.214	0.082	0.124	0.116	15	7	7	3	5	4	WDR93	WD repeat domain 93 [Source:HGNC Symbol;Acc:HGNC:26924]	-	-	-	-	GO:0005747//mitochondrial respiratory chain complex I	GO:0005515//protein binding	GO:0022900//electron transport chain	--
ENSG00000140534	0.174	0.299	0.202	0.322	0.41	0.179	24	27.05	16	18.07	36	14	TICRR	TOPBP1 interacting checkpoint and replication regulator [Source:HGNC Symbol;Acc:HGNC:28704]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010212//response to ionizing radiation;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0033314//mitotic DNA replication checkpoint signaling	--
ENSG00000140538	0.27	0.334	0.176	0.513	0.776	0.426	26	31	11	30	45	25	NTRK3	neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033]	Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Nervous system;Cancer: overview	ko04020//Calcium signaling pathway;ko04722//Neurotrophin signaling pathway;ko05230//Central carbon metabolism in cancer	K05101;K05101;K05101	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0043235//receptor complex;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005030//neurotrophin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043121//neurotrophin binding	GO:0001764//neuron migration;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0032148//activation of protein kinase B activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0038179//neurotrophin signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0045471//response to ethanol;GO:0048013//ephrin receptor signaling pathway;GO:0048665//neuron fate specification;GO:0048678//response to axon injury;GO:0048712//negative regulation of astrocyte differentiation;GO:0050927//positive regulation of positive chemotaxis;GO:0051412//response to corticosterone;GO:0051896//regulation of protein kinase B signaling;GO:0060548//negative regulation of cell death;GO:0071300//cellular response to retinoic acid;GO:0090102//cochlea development;GO:0090630//activation of GTPase activity;GO:0099151//regulation of postsynaptic density assembly;GO:1905606//regulation of presynapse assembly;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000140543	3.36	4.132	3.439	5.78	3.776	3.496	159.91	195.85	121.88	203	147.96	117.81	DET1	DET1 partner of COP1 E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:25477]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10571	GO:0005634//nucleus;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044877//protein-containing complex binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0065003//protein-containing complex assembly	--
ENSG00000140545	128.299	138.874	105.546	217.525	230.868	192.085	4775	5198	2958	6242	7493	5299	MFGE8	milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0001786//phosphatidylserine binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0008429//phosphatidylethanolamine binding	"GO:0001525//angiogenesis;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0043277//apoptotic cell clearance;GO:0050766//positive regulation of phagocytosis"	--
ENSG00000140548	3.629	3.724	3.699	2.7	3.563	2.848	352	363	265	194	292	201	ZNF710	zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000140553	33.28	34.751	37.776	39.877	35.35	38.624	2300	2398	1937	2052	2073	1945	UNC45A	unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:HGNC:30594]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0051879//Hsp90 protein binding	GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0061077//chaperone-mediated protein folding	--
ENSG00000140557	1.008	0.673	0.785	1.418	1.575	0.937	58	78	54	96	99	76	ST8SIA2	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033691//sialic acid binding"	GO:0001574//ganglioside biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0007399//nervous system development;GO:0009311//oligosaccharide metabolic process;GO:0030182//neuron differentiation;GO:0042220//response to cocaine;GO:0051965//positive regulation of synapse assembly;GO:0097503//sialylation;GO:1901216//positive regulation of neuron death;GO:1990138//neuron projection extension	--
ENSG00000140563	0.451	0.51	0.438	0.232	0.679	0.5	62	59	44	20	46	33	MCTP2	multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030672//synaptic vesicle membrane	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0019722//calcium-mediated signaling;GO:0046928//regulation of neurotransmitter secretion	--
ENSG00000140564	29.587	28.669	29.687	30.767	31.237	30.435	2572	2505	1906	1938	2297	1925	FURIN	"furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0048406//nerve growth factor binding;GO:1904399//heparan sulfate binding	GO:0001825//blastocyst formation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0019058//viral life cycle;GO:0019082//viral protein processing;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0031638//zymogen activation;GO:0032374//regulation of cholesterol transport;GO:0032804//negative regulation of low-density lipoprotein particle receptor catabolic process;GO:0032902//nerve growth factor production;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0032940//secretion by cell;GO:0042176//regulation of protein catabolic process;GO:0043043//peptide biosynthetic process;GO:0051004//regulation of lipoprotein lipase activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0052548//regulation of endopeptidase activity;GO:0090472//dibasic protein processing;GO:1901394//positive regulation of transforming growth factor beta1 activation;GO:1990000//amyloid fibril formation	--
ENSG00000140575	31.258	25.653	22.982	16.034	20.217	20.374	4322	3686	2480	1742	2426	2013	IQGAP1	IQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:6110]	Cellular Processes;Human Diseases;Cellular Processes	Cell motility;Cancer: overview;Cellular community - eukaryotes	ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04520//Adherens junction	K16848;K16848;K16848	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0030496//midbody;GO:0030667//secretory granule membrane;GO:0030864//cortical actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031252//cell leading edge;GO:0036057//slit diaphragm;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043005//neuron projection;GO:0070062//extracellular exosome;GO:0120025//plasma membrane bounded cell projection;GO:1990904//ribonucleoprotein complex	"GO:0005078//MAP-kinase scaffold activity;GO:0005095//GTPase inhibitor activity;GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0031267//small GTPase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0044548//S100 protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0060090//molecular adaptor activity"	GO:0001817//regulation of cytokine production;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007346//regulation of mitotic cell cycle;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010761//fibroblast migration;GO:0016477//cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0035305//negative regulation of dephosphorylation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0043086//negative regulation of catalytic activity;GO:0043087//regulation of GTPase activity;GO:0043410//positive regulation of MAPK cascade;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045860//positive regulation of protein kinase activity;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0071277//cellular response to calcium ion;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0072015//glomerular visceral epithelial cell development;GO:1990138//neuron projection extension	--
ENSG00000140577	6.205	6.384	6.774	7.031	7.126	8.439	671	687	512	563	651	664	CRTC3	CREB regulated transcription coactivator 3 [Source:HGNC Symbol;Acc:HGNC:26148]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K16334	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding	GO:0032793//positive regulation of CREB transcription factor activity;GO:0042116//macrophage activation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050995//negative regulation of lipid catabolic process;GO:0051289//protein homotetramerization;GO:0071878//negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0097009//energy homeostasis	--
ENSG00000140598	8.336	8.201	6.998	5.671	6.537	7.757	628	605	372	319	417	382	EFL1	elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14536	GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0043022//ribosome binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0042254//ribosome biogenesis;GO:0042256//mature ribosome assembly;GO:0046039//GTP metabolic process	--
ENSG00000140600	1.939	1.96	2.571	2.188	2.346	2.974	69	69	68	58	70	76	SH3GL3	"SH3 domain containing GRB2 like 3, endophilin A3 [Source:HGNC Symbol;Acc:HGNC:10832]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K11247	"GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0045202//synapse;GO:0098793//presynapse;GO:0098845//postsynaptic endosome;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008289//lipid binding;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0016191//synaptic vesicle uncoating;GO:0045666//positive regulation of neuron differentiation;GO:1900186//negative regulation of clathrin-dependent endocytosis;GO:2000369//regulation of clathrin-dependent endocytosis	--
ENSG00000140612	123.86	121.754	120.52	125.77	111.998	128.915	2798	2760	2014	2105	2145	2123	SEC11A	"SEC11 homolog A, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:17718]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K13280	GO:0005783//endoplasmic reticulum;GO:0005787//signal peptidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis	--
ENSG00000140623	0	0	0	0	0	0	0	0	0	0	0	0	SEPTIN12	septin 12 [Source:HGNC Symbol;Acc:HGNC:26348]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16938;K16938	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031105//septin complex;GO:0031514//motile cilium;GO:0032153//cell division site;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0097227//sperm annulus	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000140632	31.128	33.634	32.652	29.839	32.111	32.497	2158	2186	1586	1449	1775	1557	GLYR1	glyoxylate reductase 1 homolog [Source:HGNC Symbol;Acc:HGNC:24434]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031491//nucleosome binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0050661//NADP binding;GO:0051287//NAD binding	GO:0035066//positive regulation of histone acetylation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000140650	9.267	8.89	8.935	7.469	8.065	9.585	340.03	372	250.01	230	267.03	252	PMM2	phosphomannomutase 2 [Source:HGNC Symbol;Acc:HGNC:9115]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K17497;K17497;K17497	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043025//neuronal cell body	GO:0004615//phosphomannomutase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0006013//mannose metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0009298//GDP-mannose biosynthetic process	--
ENSG00000140675	0	0.091	0.031	0	0.054	0.037	0	4.3	1.08	0	2.15	1.04	SLC5A2	solute carrier family 5 member 2 [Source:HGNC Symbol;Acc:HGNC:11037]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005362//low-affinity glucose:sodium symporter activity;GO:0005412//glucose:sodium symporter activity;GO:0015151//alpha-glucoside transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0000017//alpha-glucoside transport;GO:0005975//carbohydrate metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0055085//transmembrane transport;GO:0098708//glucose import across plasma membrane;GO:0098719//sodium ion import across plasma membrane	--
ENSG00000140678	0	0.032	0	0	0.037	0	0	1	0	0	3	0	ITGAX	integrin subunit alpha X [Source:HGNC Symbol;Acc:HGNC:6152]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Cell motility;Immune system	ko05152//Tuberculosis;ko04810//Regulation of actin cytoskeleton;ko04610//Complement and coagulation cascades	K06462;K06462;K06462	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0034689//integrin alphaX-beta2 complex;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0031643//positive regulation of myelination;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0045766//positive regulation of angiogenesis;GO:0051607//defense response to virus;GO:0098609//cell-cell adhesion;GO:1905956//positive regulation of endothelial tube morphogenesis	--
ENSG00000140682	11.985	12.638	11.416	9.37	10.157	11.924	411	390	313	214	301	262	TGFB1I1	transforming growth factor beta 1 induced transcript 1 [Source:HGNC Symbol;Acc:HGNC:11767]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0062023//collagen-containing extracellular matrix	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0048495//Roundabout binding;GO:0050681//androgen receptor binding;GO:0070411//I-SMAD binding	"GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016055//Wnt signaling pathway;GO:0016331//morphogenesis of embryonic epithelium;GO:0030154//cell differentiation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030855//epithelial cell differentiation;GO:0045165//cell fate commitment;GO:0045599//negative regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000140688	38.111	41.414	42.634	52.212	46.751	46.467	2114	2403.7	1818.92	2164	2277.85	1944.96	RUSF1	RUS family member 1 [Source:HGNC Symbol;Acc:HGNC:25848]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000140691	3.101	3.464	3.566	3.198	3.489	3.298	215	245	183	166	206	169	ARMC5	armadillo repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:25781]	Human Diseases	Endocrine and metabolic disease	ko04934//Cushing syndrome	K22499	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane	GO:0005515//protein binding	"GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0007369//gastrulation;GO:0009653//anatomical structure morphogenesis;GO:0035801//adrenal cortex development;GO:0042098//T cell proliferation;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0050810//regulation of steroid biosynthetic process;GO:0051607//defense response to virus"	--
ENSG00000140694	14.124	13.19	12.487	11.691	11.348	12.731	743	716	490	474	527	480	PARN	poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:HGNC:8609]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K01148	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0070034//telomerase RNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000495//box H/ACA RNA 3'-end processing;GO:0006402//mRNA catabolic process;GO:0007292//female gamete generation;GO:0009451//RNA modification;GO:0010587//miRNA catabolic process;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0090669//telomerase RNA stabilization;GO:0110008//ncRNA deadenylation;GO:1904872//regulation of telomerase RNA localization to Cajal body"	--
ENSG00000140718	80.039	86.264	75.514	72.426	80.173	79.66	2984.65	3223.97	2145.14	2039.42	2515.15	2223.01	FTO	FTO alpha-ketoglutarate dependent dioxygenase [Source:HGNC Symbol;Acc:HGNC:24678]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0035515//oxidative RNA demethylase activity;GO:0035516//oxidative DNA demethylase activity;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:1990931//mRNA N6-methyladenosine dioxygenase activity;GO:1990984//tRNA demethylase activity	GO:0001659//temperature homeostasis;GO:0006307//DNA dealkylation involved in DNA repair;GO:0010883//regulation of lipid storage;GO:0035552//oxidative single-stranded DNA demethylation;GO:0035553//oxidative single-stranded RNA demethylation;GO:0040014//regulation of multicellular organism growth;GO:0042245//RNA repair;GO:0044065//regulation of respiratory system process;GO:0060612//adipose tissue development;GO:0061157//mRNA destabilization;GO:0070350//regulation of white fat cell proliferation;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:0090335//regulation of brown fat cell differentiation	--
ENSG00000140740	71.117	68.948	69.399	72.954	67.616	76.447	2359	2482	1715	1779	2109	1880	UQCRC2	ubiquinol-cytochrome c reductase core protein 2 [Source:HGNC Symbol;Acc:HGNC:12586]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415;K00415	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0070469//respirasome	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006119//oxidative phosphorylation;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0006508//proteolysis;GO:0009060//aerobic respiration;GO:0045333//cellular respiration"	--
ENSG00000140743	49.452	51.847	50.228	48.509	47.695	53.12	2426	2448	1801	1708	1979	1820	CDR2	cerebellar degeneration related protein 2 [Source:HGNC Symbol;Acc:HGNC:1799]	-	-	-	-	GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	-	--
ENSG00000140749	0.053	0	0	0.024	0.021	0	3	0	0	1	1	0	IGSF6	immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity	GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000140750	21.739	20.153	21.417	19.13	20.207	21.84	1204	1192	928	764	1005	911	ARHGAP17	Rho GTPase activating protein 17 [Source:HGNC Symbol;Acc:HGNC:18239]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K20638	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0017156//calcium-ion regulated exocytosis;GO:0032956//regulation of actin cytoskeleton organization;GO:0035020//regulation of Rac protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000140795	0.122	0.054	0.008	0.081	0.036	0.033	15	9	1	5	5	4	MYLK3	myosin light chain kinase 3 [Source:HGNC Symbol;Acc:HGNC:29826]	Environmental Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cellular community - eukaryotes;Signal transduction;Endocrine system;Signal transduction;Circulatory system;Immune system;Digestive system	ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04971//Gastric acid secretion	K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004687//myosin light chain kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0045214//sarcomere organization;GO:0048769//sarcomerogenesis;GO:0055003//cardiac myofibril assembly;GO:0060298//positive regulation of sarcomere organization;GO:0071347//cellular response to interleukin-1	--
ENSG00000140798	0	0	0	0	0	0.019	0	0	0	0	0	1	ABCC12	ATP binding cassette subfamily C member 12 [Source:HGNC Symbol;Acc:HGNC:14640]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05672	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0055085//transmembrane transport	--
ENSG00000140807	0.119	0.127	0.065	0.222	0.151	0.187	42	45	17	58	45	48	NKD1	NKD inhibitor of WNT signaling pathway 1 [Source:HGNC Symbol;Acc:HGNC:17045]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04390//Hippo signaling pathway	K03213;K03213	GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0046872//metal ion binding	"GO:0001754//eye photoreceptor cell differentiation;GO:0007525//somatic muscle development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090249//regulation of cell migration involved in somitogenic axis elongation;GO:1901231//positive regulation of non-canonical Wnt signaling pathway via JNK cascade;GO:1901233//negative regulation of convergent extension involved in axis elongation;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000140829	8.915	10.006	10.316	8.871	10.351	10.202	788	843	634.91	579.83	707	653	DHX38	DEAH-box helicase 38 [Source:HGNC Symbol;Acc:HGNC:17211]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12815	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000140830	1.893	1.161	3.025	1.73	3.417	1.84	99	61	77	67	127	70	TXNL4B	thioredoxin like 4B [Source:HGNC Symbol;Acc:HGNC:26041]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005829//cytosol;GO:0046540//U4/U6 x U5 tri-snRNP complex	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing"	--
ENSG00000140832	1.815	2.243	2.058	3.01	2.337	2.207	91.23	104.26	64.94	102.94	88.47	60.61	MARVELD3	MARVEL domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30525]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21099	GO:0005737//cytoplasm;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding	GO:0006970//response to osmotic stress;GO:0010633//negative regulation of epithelial cell migration;GO:0045216//cell-cell junction organization;GO:0046329//negative regulation of JNK cascade;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070830//bicellular tight junction assembly;GO:1902414//protein localization to cell junction	--
ENSG00000140835	0	0	0.03	0	0	0	0	0	1	0	0	0	CHST4	carbohydrate sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:1972]	Metabolism	Glycan biosynthesis and metabolism	ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K04746	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031228//intrinsic component of Golgi membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006477//protein sulfation;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0016266//O-glycan processing;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000140836	2.222	1.717	1.64	1.173	1.458	1.318	725	559	389	285	398	311	ZFHX3	zinc finger homeobox 3 [Source:HGNC Symbol;Acc:HGNC:777]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09378	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007517//muscle organ development;GO:0032922//circadian regulation of gene expression;GO:0045662//negative regulation of myoblast differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045664//regulation of neuron differentiation;GO:0045785//positive regulation of cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0071559//response to transforming growth factor beta;GO:1904059//regulation of locomotor rhythm"	Homeobox
ENSG00000140839	0.166	0.505	0.258	0	0.28	0.14	6.62	20.24	7.6	0	9.45	4.06	CLEC18B	C-type lectin domain family 18 member B [Source:HGNC Symbol;Acc:HGNC:33849]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016529//sarcoplasmic reticulum	GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding	-	--
ENSG00000140848	13.108	14.556	15.336	12.508	16.414	13.398	615	680	510	425	622	462	CPNE2	copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0071277//cellular response to calcium ion	--
ENSG00000140853	1.811	2.079	1.892	2.438	2.651	2.433	197	219	179	208	272	230	NLRC5	NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0002376//immune system process;GO:0009617//response to bacterium;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0035556//intracellular signal transduction;GO:0043549//regulation of kinase activity;GO:0045087//innate immune response;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway	--
ENSG00000140854	8.994	11.009	11.288	12.381	11.317	9.703	463	521	398	443	451	351	KATNB1	katanin regulatory subunit B1 [Source:HGNC Symbol;Acc:HGNC:6217]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0008352//katanin complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0030496//midbody;GO:0043025//neuronal cell body	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0046982//protein heterodimerization activity;GO:0060590//ATPase regulator activity;GO:0070840//dynein complex binding	GO:0006605//protein targeting;GO:0007019//microtubule depolymerization;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0010942//positive regulation of cell death;GO:0010976//positive regulation of neuron projection development;GO:0031117//positive regulation of microtubule depolymerization;GO:0051013//microtubule severing;GO:0051301//cell division	--
ENSG00000140859	3.177	5.813	3.457	4.785	6.311	6.135	195	227	122	167	243	196	KIFC3	kinesin family member C3 [Source:HGNC Symbol;Acc:HGNC:6326]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0042802//identical protein binding	GO:0007017//microtubule-based process;GO:0007018//microtubule-based movement;GO:0007030//Golgi organization;GO:0007601//visual perception;GO:0045218//zonula adherens maintenance;GO:0090136//epithelial cell-cell adhesion	--
ENSG00000140873	0.157	0.164	0	0.167	0.117	0.045	19	20	0	15	12	4	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif 18 [Source:HGNC Symbol;Acc:HGNC:17110]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001654//eye development;GO:0006508//proteolysis;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0090331//negative regulation of platelet aggregation	--
ENSG00000140876	7.182	7.376	8.193	7.672	8.807	7.749	139	144	116	111	120	112	NUDT7	nudix hydrolase 7 [Source:HGNC Symbol;Acc:HGNC:8054]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K17879	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	"GO:0000287//magnesium ion binding;GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0003986//acetyl-CoA hydrolase activity;GO:0010945//CoA pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0030145//manganese ion binding;GO:0030515//snoRNA binding;GO:0046872//metal ion binding"	GO:0008150//biological_process;GO:0009132//nucleoside diphosphate metabolic process;GO:0015938//coenzyme A catabolic process;GO:0036114//medium-chain fatty-acyl-CoA catabolic process;GO:0044580//butyryl-CoA catabolic process;GO:0046356//acetyl-CoA catabolic process;GO:0050873//brown fat cell differentiation;GO:1901289//succinyl-CoA catabolic process;GO:1902858//propionyl-CoA metabolic process;GO:1902859//propionyl-CoA catabolic process;GO:2001294//malonyl-CoA catabolic process	--
ENSG00000140905	28.68	23.772	24.277	25.586	22.463	25.98	855.35	774.93	579.78	582.36	575.45	594.74	GCSH	glycine cleavage system protein H [Source:HGNC Symbol;Acc:HGNC:4208]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K02437;K02437;K02437;K02437	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005960//glycine cleavage complex;GO:1990204//oxidoreductase complex	GO:0004047//aminomethyltransferase activity;GO:0005515//protein binding	GO:0006546//glycine catabolic process;GO:0009249//protein lipoylation;GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0044281//small molecule metabolic process	--
ENSG00000140931	15.198	17.106	16.746	11.582	13.926	10.157	566	586	364	322	367	286	CMTM3	CKLF like MARVEL transmembrane domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19174]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0001835//blastocyst hatching;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0050861//positive regulation of B cell receptor signaling pathway	--
ENSG00000140932	0	0	0	0	0	0	0	0	0	0	0	0	CMTM2	CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006935//chemotaxis;GO:0007165//signal transduction	--
ENSG00000140937	29.537	30.834	15.14	21.737	30.28	26.15	1954	1845	544	1107	1501	1121	CDH11	cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0021957//corticospinal tract morphogenesis;GO:0034332//adherens junction organization;GO:0050804//modulation of chemical synaptic transmission;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000140939	6.635	7.394	5.586	7.657	6.93	4.795	198	220	118	166	167	105	NOL3	nucleolar protein 3 [Source:HGNC Symbol;Acc:HGNC:7869]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016528//sarcoplasm;GO:0016529//sarcoplasmic reticulum	GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005123//death receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0035877//death effector domain binding;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0089720//caspase binding	GO:0001666//response to hypoxia;GO:0001974//blood vessel remodeling;GO:0002931//response to ischemia;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0010659//cardiac muscle cell apoptotic process;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0014736//negative regulation of muscle atrophy;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014876//response to injury involved in regulation of muscle adaptation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0051259//protein complex oligomerization;GO:0060547//negative regulation of necrotic cell death;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000140941	56.372	56.719	54.609	49.592	52.423	56.408	2529.96	2565.9	1803.67	1640.91	1990	1851.59	MAP1LC3B	microtubule associated protein 1 light chain 3 beta [Source:HGNC Symbol;Acc:HGNC:13352]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Transport and catabolism;Signal transduction;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04216//Ferroptosis	K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005930//axoneme;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding;GO:0097001//ceramide binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0016236//macroautophagy;GO:0097352//autophagosome maturation	--
ENSG00000140943	51.711	52.405	51.94	46.648	50.801	49.008	4579	4701	3323	3054	3836	3178	MBTPS1	"membrane bound transcription factor peptidase, site 1 [Source:HGNC Symbol;Acc:HGNC:15456]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K08653	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0007040//lysosome organization;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034976//response to endoplasmic reticulum stress;GO:0036500//ATF6-mediated unfolded protein response;GO:0045540//regulation of cholesterol biosynthetic process;GO:0060627//regulation of vesicle-mediated transport	--
ENSG00000140945	1.278	1.021	0.797	0.892	0.509	0.771	64	43	31	23	28	16	CDH13	cadherin 13 [Source:HGNC Symbol;Acc:HGNC:1753]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016342//catenin complex;GO:0031225//anchored component of membrane;GO:0043005//neuron projection;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0055100//adiponectin binding;GO:0071813//lipoprotein particle binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002040//sprouting angiogenesis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007162//negative regulation of cell adhesion;GO:0007266//Rho protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016601//Rac protein signal transduction;GO:0030032//lamellipodium assembly;GO:0030100//regulation of endocytosis;GO:0030335//positive regulation of cell migration;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043542//endothelial cell migration;GO:0043616//keratinocyte proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050927//positive regulation of positive chemotaxis;GO:0051668//localization within membrane;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000140948	8.75	8.497	8.684	7.557	8.11	7.964	1300	1262	953	826	1031	875	ZCCHC14	zinc finger CCHC-type containing 14 [Source:HGNC Symbol;Acc:HGNC:24134]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	-	--
ENSG00000140950	7.246	7.953	8.641	8.514	8.918	7.026	505	568	458	462	526	415	MEAK7	"MTOR associated protein, eak-7 homolog [Source:HGNC Symbol;Acc:HGNC:29325]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	GO:0030334//regulation of cell migration;GO:0031667//response to nutrient levels;GO:0031929//TOR signaling;GO:0032868//response to insulin;GO:0042127//regulation of cell population proliferation;GO:0043200//response to amino acid;GO:0150032//positive regulation of protein localization to lysosome;GO:1903204//negative regulation of oxidative stress-induced neuron death	--
ENSG00000140955	3.034	3.066	3.752	5.128	4.642	4.466	127	129	116	159	165	136	ADAD2	adenosine deaminase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30714]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0004000//adenosine deaminase activity;GO:0008251//tRNA-specific adenosine deaminase activity	GO:0006382//adenosine to inosine editing;GO:0006396//RNA processing;GO:0007286//spermatid development	--
ENSG00000140961	3.578	2.87	3.363	4.482	2.798	4.478	122	115	93	130	95	119	OSGIN1	oxidative stress induced growth inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:30093]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030334//regulation of cell migration;GO:0040008//regulation of growth;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process	--
ENSG00000140968	0	0	0	0	0.121	0	0	0	0	0	2	0	IRF8	interferon regulatory factor 8 [Source:HGNC Symbol;Acc:HGNC:5358]	Human Diseases	Infectious disease: bacterial	ko05133//Pertussis	K10155	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002273//plasmacytoid dendritic cell differentiation;GO:0002314//germinal center B cell differentiation;GO:0002316//follicular B cell differentiation;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006909//phagocytosis;GO:0006914//autophagy;GO:0006955//immune response;GO:0009617//response to bacterium;GO:0030099//myeloid cell differentiation;GO:0032479//regulation of type I interferon production;GO:0032729//positive regulation of interferon-gamma production;GO:0032735//positive regulation of interleukin-12 production;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0097028//dendritic cell differentiation"	IRF
ENSG00000140983	14.369	19.036	18.68	20.441	20.259	23.123	628	745	545	650	746	656	RHOT2	ras homolog family member T2 [Source:HGNC Symbol;Acc:HGNC:21169]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K07871	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0007005//mitochondrion organization;GO:0007264//small GTPase mediated signal transduction;GO:0010821//regulation of mitochondrion organization;GO:0019725//cellular homeostasis;GO:0047497//mitochondrion transport along microtubule;GO:0097345//mitochondrial outer membrane permeabilization	--
ENSG00000140986	1.191	1.029	1.735	2.488	2.501	2.193	53	46	57	82	94	71	RPL3L	ribosomal protein L3 like [Source:HGNC Symbol;Acc:HGNC:10351]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02925;K02925	GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0000027//ribosomal large subunit assembly;GO:0006412//translation	--
ENSG00000140987	6.325	6.583	5.762	4.36	5.273	6.088	337	358	252	179	232	239	ZSCAN32	zinc finger and SCAN domain containing 32 [Source:HGNC Symbol;Acc:HGNC:20812]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000140988	1292.406	1392.595	1276.643	1577.736	1440.176	1224.995	25330	27429	18482	22907	23850	17470	RPS2	ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02981;K02981	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0019899//enzyme binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0051443//positive regulation of ubiquitin-protein transferase activity	--
ENSG00000140990	53.024	56.612	69.376	74.875	59.508	67.669	676	753	655	735	656	627	NDUFB10	NADH:ubiquinone oxidoreductase subunit B10 [Source:HGNC Symbol;Acc:HGNC:7696]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966;K03966	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000140992	11.343	11.787	12.241	12.162	11.381	12.41	1568	1625	1220	1145	1381	1175	PDPK1	3-phosphoinositide dependent protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:8816]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Cancer: overview;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Development and regeneration;Signal transduction;Transport and catabolism;Endocrine system;Cell growth and death;Immune system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Cancer: overview;Cancer: specific types;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Excretory system	ko04151//PI3K-Akt signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04360//Axon guidance;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko03320//PPAR signaling pathway;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko05213//Endometrial cancer;ko04960//Aldosterone-regulated sodium reabsorption	K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276;K06276	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004676//3-phosphoinositide-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043274//phospholipase binding;GO:0106310//protein serine kinase activity	GO:0003323//type B pancreatic cell development;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006972//hyperosmotic response;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010518//positive regulation of phospholipase activity;GO:0010594//regulation of endothelial cell migration;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019722//calcium-mediated signaling;GO:0030036//actin cytoskeleton organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0032869//cellular response to insulin stimulus;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043304//regulation of mast cell degranulation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0046777//protein autophosphorylation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903672//positive regulation of sprouting angiogenesis;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000140993	2.456	3.01	2.059	2.569	1.633	2.191	174.27	214.7	107.91	135.03	97.92	113.13	TIGD7	tigger transposable element derived 7 [Source:HGNC Symbol;Acc:HGNC:18331]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000140995	25.404	27.343	24.279	29.88	30.153	28.265	1125	1216	874	1022	1187	961	DEF8	differentially expressed in FDCP 8 homolog [Source:HGNC Symbol;Acc:HGNC:25969]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0032418//lysosome localization;GO:0045780//positive regulation of bone resorption;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000141002	58.58	60.75	54.727	54.6	55.751	53.704	2401	2528.79	1791	1781	1951	1650	TCF25	transcription factor 25 [Source:HGNC Symbol;Acc:HGNC:29181]	-	-	-	-	GO:0005634//nucleus;GO:1990112//RQC complex	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007507//heart development	Others
ENSG00000141012	6.417	7.892	6.336	7.34	7.362	8.158	312	375	224	257	294	272	GALNS	galactosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4122]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01132;K01132;K01132	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0043890//N-acetylgalactosamine-6-sulfatase activity;GO:0046872//metal ion binding	-	--
ENSG00000141013	6.413	6.619	5.471	5.702	6.04	6.91	311	340	227	194	265	256	GAS8	growth arrest specific 8 [Source:HGNC Symbol;Acc:HGNC:4166]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031267//small GTPase binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0030317//flagellated sperm motility;GO:0034613//cellular protein localization;GO:0035082//axoneme assembly;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048870//cell motility;GO:0051179//localization;GO:0060294//cilium movement involved in cell motility;GO:1903566//positive regulation of protein localization to cilium;GO:1904526//regulation of microtubule binding	--
ENSG00000141026	8.712	8.62	10.568	9.929	9.131	9.269	393	397	346	337	339	309	MED9	mediator complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:25487]	-	-	-	-	GO:0005634//nucleus;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000141027	19.841	17.197	15.936	11.23	16.137	13.303	2111	1970	1337	941.08	1299	1187	NCOR1	nuclear receptor corepressor 1 [Source:HGNC Symbol;Acc:HGNC:7672]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Endocrine system;Drug resistance: antineoplastic	ko05202//Transcriptional misregulation in cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance	K04650;K04650;K04650	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017053//transcription repressor complex;GO:0072686//mitotic spindle	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0042826//histone deacetylase binding;GO:0046966//thyroid hormone receptor binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045475//locomotor rhythm;GO:0045820//negative regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045922//negative regulation of fatty acid metabolic process;GO:0046329//negative regulation of JNK cascade;GO:0048511//rhythmic process;GO:0051225//spindle assembly;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA"	MYB
ENSG00000141030	21.75	20.533	22.078	21.742	17.503	21.064	644	661	480	501	448	496	COPS3	COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	"GO:0000338//protein deneddylation;GO:0001701//in utero embryonic development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0009416//response to light stimulus;GO:0045116//protein neddylation;GO:1902162//regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:2000434//regulation of protein neddylation"	--
ENSG00000141034	8.679	8.425	8.572	6.961	8.165	8.198	742	724	538	425	554	510	GID4	GID complex subunit 4 homolog [Source:HGNC Symbol;Acc:HGNC:28453]	-	-	-	-	GO:0000151//ubiquitin ligase complex	GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000141040	2.838	2.351	2.272	1.719	1.794	1.643	249	216	163	115	144	121	ZNF287	zinc finger protein 287 [Source:HGNC Symbol;Acc:HGNC:13502]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0001817//regulation of cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000141052	0.375	0.373	0.7	0.296	0.565	0.332	61	55	63	39	35	39	MYOCD	myocardin [Source:HGNC Symbol;Acc:HGNC:16067]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding;GO:0042826//histone deacetylase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412//R-SMAD binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001560//regulation of cell growth by extracellular stimulus;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0003231//cardiac ventricle development;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010832//negative regulation of myotube differentiation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0035051//cardiocyte differentiation;GO:0035065//regulation of histone acetylation;GO:0035886//vascular associated smooth muscle cell differentiation;GO:0042692//muscle cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0043954//cellular component maintenance;GO:0045661//regulation of myoblast differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045987//positive regulation of smooth muscle contraction;GO:0048286//lung alveolus development;GO:0048565//digestive tract development;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051145//smooth muscle cell differentiation;GO:0051150//regulation of smooth muscle cell differentiation;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060065//uterus development;GO:0060157//urinary bladder development;GO:0060354//negative regulation of cell adhesion molecule production;GO:0097070//ductus arteriosus closure;GO:1900222//negative regulation of amyloid-beta clearance;GO:1900239//regulation of phenotypic switching;GO:1901228//positive regulation of transcription from RNA polymerase II promoter involved in heart development;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:2000724//positive regulation of cardiac vascular smooth muscle cell differentiation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:2001015//negative regulation of skeletal muscle cell differentiation"	--
ENSG00000141068	11.728	13.492	15.59	15.868	15.693	14.145	1065	1121	877	735	1022	734	KSR1	kinase suppressor of ras 1 [Source:HGNC Symbol;Acc:HGNC:6465]	Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Signal transduction;Immune system	ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko04625//C-type lectin receptor signaling pathway	K14958;K14958;K14958	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0016310//phosphorylation;GO:0019933//cAMP-mediated signaling;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0043405//regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000141076	10.939	11.422	12.369	13.233	11.213	11.782	488	521	364	398	421	389	UTP4	UTP4 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:1983]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14548	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030686//90S preribosome;GO:0032040//small-subunit processome;GO:0034455//t-UTP complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006355//regulation of transcription, DNA-templated;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis"	--
ENSG00000141084	6.889	6.336	6.799	7.013	6.832	6.72	629	610	474	456	526	455	RANBP10	RAN binding protein 10 [Source:HGNC Symbol;Acc:HGNC:29285]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000141086	0.249	0.371	0.056	0.056	0	0.057	3	9	1	1	0	1	CTRL	chymotrypsin like [Source:HGNC Symbol;Acc:HGNC:2524]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K09632;K09632	GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0030163//protein catabolic process	--
ENSG00000141096	0	0	0	0	0	0	0	0	0	0	0	0	DPEP3	dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity	GO:0006508//proteolysis	--
ENSG00000141098	12.157	10.313	11.107	11.754	10.978	10.08	674	643	464	455	537	463	GFOD2	glucose-fructose oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28159]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0000166//nucleotide binding;GO:0016491//oxidoreductase activity	GO:0030198//extracellular matrix organization	--
ENSG00000141101	20.485	18.468	20.885	22.42	21.518	24.299	683	656	537	587	633	598	NOB1	NIN1 (RPN12) binding protein 1 homolog [Source:HGNC Symbol;Acc:HGNC:29540]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11883	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor"	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000469//cleavage involved in rRNA processing;GO:0006364//rRNA processing;GO:0007601//visual perception;GO:0030490//maturation of SSU-rRNA;GO:0042274//ribosomal small subunit biogenesis;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000141127	14.897	14.201	12.512	14.404	13.358	12.617	484	411	317	300	341	288	PRPSAP2	phosphoribosyl pyrophosphate synthetase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:9467]	-	-	-	-	GO:0002189//ribose phosphate diphosphokinase complex;GO:0005737//cytoplasm	GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0043086//negative regulation of catalytic activity;GO:0060348//bone development	--
ENSG00000141161	0	0	0	0	0	0	0	0	0	0	0	0	UNC45B	unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0051879//Hsp90 protein binding	GO:0002088//lens development in camera-type eye;GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0061077//chaperone-mediated protein folding	--
ENSG00000141179	2.914	3.719	3.69	2.75	2.676	3.255	109	126	103	79	84	88	PCTP	phosphatidylcholine transfer protein [Source:HGNC Symbol;Acc:HGNC:8752]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008525//phosphatidylcholine transporter activity;GO:0031210//phosphatidylcholine binding	GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000141194	0	0	0	0	0	0	0	0	0	0	0	0	OR4D1	olfactory receptor family 4 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:8293]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000141198	25.492	21.963	23.027	17.913	21.277	22.159	989.36	860.93	662.84	498.43	646.89	598.26	TOM1L1	target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0030276//clathrin binding;GO:0030295//protein kinase activator activity;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0031954//positive regulation of protein autophosphorylation;GO:0032147//activation of protein kinase activity;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045839//negative regulation of mitotic nuclear division	--
ENSG00000141200	0	0	0	0	0	0	0	0	0	0	0	0	KIF2B	kinesin family member 2B [Source:HGNC Symbol;Acc:HGNC:29443]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K10393	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle"	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0007049//cell cycle;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0051983//regulation of chromosome segregation	--
ENSG00000141219	11.268	10.513	12.365	9.337	10.798	12.123	726	719	587	468	587	531	C17orf80	chromosome 17 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:29601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000141232	27.965	26.522	28.123	20.953	23.424	22.028	1247	1214	945	718	866	744	TOB1	"transducer of ERBB2, 1 [Source:HGNC Symbol;Acc:HGNC:11979]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030014//CCR4-NOT complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0046332//SMAD binding	"GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0017148//negative regulation of translation;GO:0030514//negative regulation of BMP signaling pathway;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060212//negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0060390//regulation of SMAD protein signal transduction;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	--
ENSG00000141252	10.124	10.426	8.549	9.074	7.765	7.769	979	1106.04	745	671	734	620.01	VPS53	VPS53 subunit of GARP complex [Source:HGNC Symbol;Acc:HGNC:25608]	-	-	-	-	GO:0000938//GARP complex;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:1990745//EARP complex	GO:0005515//protein binding	"GO:0007041//lysosomal transport;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000141255	0.14	0.039	0.149	0	0	0.959	4	1	3	0	0	3.81	SPATA22	spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705]	-	-	-	-	GO:0005694//chromosome	GO:0005515//protein binding	GO:0000711//meiotic DNA repair synthesis;GO:0007129//homologous chromosome pairing at meiosis;GO:0007276//gamete generation;GO:0051321//meiotic cell cycle;GO:0051445//regulation of meiotic cell cycle	--
ENSG00000141258	21.647	20.511	22.792	22.853	23.365	20.398	1890	1897	1358	1378	1643	1259	SGSM2	small G protein signaling modulator 2 [Source:HGNC Symbol;Acc:HGNC:29026]	-	-	-	-	GO:0005737//cytoplasm;GO:0042470//melanosome	GO:0005096//GTPase activator activity;GO:0031267//small GTPase binding	GO:0034499//late endosome to Golgi transport;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000141279	36.74	39.421	43.791	36.777	38.901	37.858	3135	2900	2178	1920	2318	1937	NPEPPS	aminopeptidase puromycin sensitive [Source:HGNC Symbol;Acc:HGNC:7900]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0000209//protein polyubiquitination;GO:0006508//proteolysis;GO:0043171//peptide catabolic process;GO:0071456//cellular response to hypoxia;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000141293	0	0	0.133	0	0.037	0	0	0	3	0	1	0	SKAP1	src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17699	GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0042101//T cell receptor complex;GO:0044853//plasma membrane raft	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042169//SH2 domain binding	"GO:0001954//positive regulation of cell-matrix adhesion;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002821//positive regulation of adaptive immune response;GO:0033625//positive regulation of integrin activation;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0045785//positive regulation of cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050852//T cell receptor signaling pathway;GO:0072659//protein localization to plasma membrane;GO:1903039//positive regulation of leukocyte cell-cell adhesion"	--
ENSG00000141294	1.303	1.158	2.06	0.716	1.249	1.273	46	44	48	21	29	25	LRRC46	leucine rich repeat containing 46 [Source:HGNC Symbol;Acc:HGNC:25047]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000141295	11.229	10.976	13.255	13.623	14.849	15.06	366	362	328	329	401	368	SCRN2	secernin 2 [Source:HGNC Symbol;Acc:HGNC:30381]	-	-	-	-	GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016805//dipeptidase activity;GO:0070004//cysteine-type exopeptidase activity	GO:0006508//proteolysis;GO:0008150//biological_process	--
ENSG00000141298	4.873	5.612	3.867	3.56	3.654	6.789	560	594	441	405	536	490	SSH2	slingshot protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:30580]	Cellular Processes;Organismal Systems	Cell motility;Development and regeneration	ko04810//Regulation of actin cytoskeleton;ko04360//Axon guidance	K05766;K05766	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030335//positive regulation of cell migration;GO:0030837//negative regulation of actin filament polymerization;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000141314	0.142	0.165	0.115	0.117	0.026	0.015	7	8	5	5	2	1	RHBDL3	rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000141316	0	0	0	0	0.136	0	0	0	0	0	2	0	SPACA3	sperm acrosome associated 3 [Source:HGNC Symbol;Acc:HGNC:16260]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0036126//sperm flagellum;GO:0043159//acrosomal matrix	GO:0003796//lysozyme activity;GO:0005515//protein binding	GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0009566//fertilization;GO:0035036//sperm-egg recognition;GO:0042117//monocyte activation;GO:0043032//positive regulation of macrophage activation;GO:0050766//positive regulation of phagocytosis	--
ENSG00000141337	4.19	4.139	4.184	3.754	4.801	4.264	318.1	332.72	231.43	203.11	282.39	226.13	ARSG	arylsulfatase G [Source:HGNC Symbol;Acc:HGNC:24102]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12381	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0033889//N-sulfoglucosamine-3-sulfatase activity;GO:0046872//metal ion binding	GO:0006790//sulfur compound metabolic process	--
ENSG00000141338	0	0	0.031	0	0.01	0	0	0	1	0	1	0	ABCA8	ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05650	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006686//sphingomyelin biosynthetic process;GO:0006869//lipid transport;GO:0010874//regulation of cholesterol efflux;GO:0010875//positive regulation of cholesterol efflux;GO:0030301//cholesterol transport;GO:0033344//cholesterol efflux;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport	--
ENSG00000141349	88.773	96.736	93.291	109.641	110.264	93.988	2638	2894.4	2135	2501	2811	2132	G6PC3	glucose-6-phosphatase catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:24861]	Metabolism;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism;Endocrine system;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko04920//Adipocytokine signaling pathway;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004346//glucose-6-phosphatase activity;GO:0016787//hydrolase activity	GO:0006094//gluconeogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0015760//glucose-6-phosphate transport;GO:0016311//dephosphorylation;GO:0051156//glucose 6-phosphate metabolic process	--
ENSG00000141367	95.861	81.071	79.136	66.327	76.642	72.389	10681	9350	6715	5342	7015	5981	CLTC	clathrin heavy chain [Source:HGNC Symbol;Acc:HGNC:2092]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Transport and catabolism;Infectious disease: bacterial;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04142//Lysosome;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K04646;K04646;K04646;K04646;K04646;K04646	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030118//clathrin coat;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0032991//protein-containing complex;GO:0036020//endolysosome membrane;GO:0042470//melanosome;GO:0045334//clathrin-coated endocytic vesicle;GO:0070062//extracellular exosome;GO:0071439//clathrin complex;GO:0072686//mitotic spindle;GO:1903561//extracellular vesicle;GO:1990498//mitotic spindle microtubule	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0032051//clathrin light chain binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0097718//disordered domain specific binding;GO:1990381//ubiquitin-specific protease binding	"GO:0000278//mitotic cell cycle;GO:0001649//osteoblast differentiation;GO:0006886//intracellular protein transport;GO:0006898//receptor-mediated endocytosis;GO:0006914//autophagy;GO:0007049//cell cycle;GO:0016192//vesicle-mediated transport;GO:0031623//receptor internalization;GO:0033572//transferrin transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0046907//intracellular transport;GO:0048268//clathrin coat assembly;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0072583//clathrin-dependent endocytosis;GO:0150093//amyloid-beta clearance by transcytosis;GO:1900126//negative regulation of hyaluronan biosynthetic process;GO:1903077//negative regulation of protein localization to plasma membrane"	--
ENSG00000141371	0	0	0	0	0	0	0	0	0	0	0	0	C17orf64	chromosome 17 open reading frame 64 [Source:HGNC Symbol;Acc:HGNC:26990]	-	-	-	-	-	-	-	--
ENSG00000141376	8.629	10.744	9.836	11.086	11.025	9.703	561	697	494	532	668	469	BCAS3	BCAS3 microtubule associated cell migration factor [Source:HGNC Symbol;Acc:HGNC:14347]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0031252//cell leading edge;GO:0035327//transcriptionally active chromatin;GO:0045111//intermediate filament cytoskeleton	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0010698//acetyltransferase activator activity;GO:0016922//nuclear receptor binding;GO:0035035//histone acetyltransferase binding;GO:0035091//phosphatidylinositol binding;GO:0042393//histone binding;GO:0048487//beta-tubulin binding	GO:0001525//angiogenesis;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0010595//positive regulation of endothelial cell migration;GO:0031023//microtubule organizing center organization;GO:0034260//negative regulation of GTPase activity;GO:0035148//tube formation;GO:0042594//response to starvation;GO:0043085//positive regulation of catalytic activity;GO:0043547//positive regulation of GTPase activity;GO:0043627//response to estrogen;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051491//positive regulation of filopodium assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0071391//cellular response to estrogen stimulus;GO:0090316//positive regulation of intracellular protein transport;GO:0090630//activation of GTPase activity;GO:2000114//regulation of establishment of cell polarity;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000141378	8.931	9.066	9.754	6.115	6.473	10.129	144	149	113	75	85	116	PTRH2	peptidyl-tRNA hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:24265]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004045//aminoacyl-tRNA hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006915//apoptotic process;GO:0010629//negative regulation of gene expression;GO:2000210//positive regulation of anoikis;GO:2000811//negative regulation of anoikis	--
ENSG00000141380	21.863	20.856	20.714	17.124	17.351	23.428	1279	1191	882	697	861	974	SS18	SS18 subunit of BAF chromatin remodeling complex [Source:HGNC Symbol;Acc:HGNC:11340]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15623	GO:0000785//chromatin;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0016514//SWI/SNF complex;GO:0071564//npBAF complex;GO:0140288//GBAF complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000226//microtubule cytoskeleton organization;GO:0000902//cell morphogenesis;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0035556//intracellular signal transduction;GO:0045596//negative regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048013//ephrin receptor signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000141384	0.535	0.716	0.179	0.247	0.437	0.446	51	68	13	18	36	32	TAF4B	TATA-box binding protein associated factor 4b [Source:HGNC Symbol;Acc:HGNC:11538]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03022//Basal transcription factors	K03129;K03129	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046982//protein heterodimerization activity;GO:0051059//NF-kappaB binding	"GO:0006351//transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0048477//oogenesis;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000141385	31.474	33.497	33.614	36.933	32.914	35.478	2060.56	2016.79	1500.91	1613.23	1819.14	1587.86	AFG3L2	AFG3 like matrix AAA peptidase subunit 2 [Source:HGNC Symbol;Acc:HGNC:315]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K08956	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005745//m-AAA complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004176//ATP-dependent peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0006508//proteolysis;GO:0007005//mitochondrion organization;GO:0007409//axonogenesis;GO:0007528//neuromuscular junction development;GO:0008053//mitochondrial fusion;GO:0016485//protein processing;GO:0016540//protein autoprocessing;GO:0021675//nerve development;GO:0033619//membrane protein proteolysis;GO:0034982//mitochondrial protein processing;GO:0036444//calcium import into the mitochondrion;GO:0040014//regulation of multicellular organism growth;GO:0042407//cristae formation;GO:0042552//myelination;GO:0051560//mitochondrial calcium ion homeostasis;GO:0055001//muscle cell development;GO:0060013//righting reflex;GO:0065003//protein-containing complex assembly	--
ENSG00000141391	1.018	0.77	1	1.42	1.011	1.522	28	28	26	18	22	23	PRELID3A	PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding;GO:1990050//phosphatidic acid transfer activity	GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000141401	18.065	19.177	23.771	28.648	23.835	29.238	495	466	413	542	554	526	IMPA2	inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01092;K01092;K01092	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0052834//inositol monophosphate phosphatase activity	GO:0006020//inositol metabolic process;GO:0006021//inositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation	--
ENSG00000141404	1.787	2.617	1.799	1.095	4.259	1.703	172.78	156.91	88.13	82.2	141.8	75.88	GNAL	G protein subunit alpha L [Source:HGNC Symbol;Acc:HGNC:4388]	Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Sensory system;Signal transduction;Neurodegenerative disease;Infectious disease: parasitic;Nervous system;Infectious disease: parasitic	ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05146//Amoebiasis;ko04728//Dopaminergic synapse;ko05142//Chagas disease	K04633;K04633;K04633;K04633;K04633;K04633	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007606//sensory perception of chemical stimulus	--
ENSG00000141424	148.509	131.73	132.95	98.348	108.661	136.035	10751	9561	7161	5265	6570	7162	SLC39A6	solute carrier family 39 member 6 [Source:HGNC Symbol;Acc:HGNC:18607]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14712;K14712	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031258//lamellipodium membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071578//zinc ion import across plasma membrane	--
ENSG00000141425	23.771	21.27	23.3	19.909	22.341	24.159	1896	1676	1256	1136	1293	1234	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A [Source:HGNC Symbol;Acc:HGNC:25560]	-	-	-	-	"GO:0005654//nucleoplasm;GO:0016591//RNA polymerase II, holoenzyme"	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0031124//mRNA 3'-end processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000141428	7.464	7.396	7.671	7.376	6.729	8.215	149	142	107	104	107	115	C18orf21	chromosome 18 open reading frame 21 [Source:HGNC Symbol;Acc:HGNC:28802]	-	-	-	-	-	-	-	--
ENSG00000141429	158.843	139.231	144.661	128.335	133.785	142.8	9683	8612	6601	5905	6698	6444	GALNT1	polypeptide N-acetylgalactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4123]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine;GO:0019082//viral protein processing	--
ENSG00000141431	0.431	0.262	0.209	0.117	0.118	0.191	48	38	18	21	24	23	ASXL3	ASXL transcriptional regulator 3 [Source:HGNC Symbol;Acc:HGNC:29357]	-	-	-	-	GO:0005634//nucleus;GO:0035517//PR-DUB complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0009887//animal organ morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051055//negative regulation of lipid biosynthetic process"	--
ENSG00000141433	0.784	0.662	0.821	1.098	0.928	1.403	53	45	41	55	53	69	ADCYAP1	adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Environmental adaptation;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04713//Circadian entrainment;ko04911//Insulin secretion;ko04924//Renin secretion	K05262;K05262;K05262;K05262;K05262	GO:0005576//extracellular region;GO:0043005//neuron projection;GO:0043204//perikaryon	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0016521//pituitary adenylate cyclase activating polypeptide activity;GO:0031858//pituitary adenylate cyclase-activating polypeptide receptor binding;GO:0051428//peptide hormone receptor binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007565//female pregnancy;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0019933//cAMP-mediated signaling;GO:0030073//insulin secretion;GO:0031175//neuron projection development;GO:0032880//regulation of protein localization;GO:0043547//positive regulation of GTPase activity;GO:0045786//negative regulation of cell cycle;GO:0045860//positive regulation of protein kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060124//positive regulation of growth hormone secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000141434	0	0	0	0	0	0	0	0	0	0	0	0	MEP1B	meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K08606	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017090//meprin A complex	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:1901998//toxin transport	--
ENSG00000141437	0	0	0	0	0	0	0	0	0	0	0	0	SLC25A52	solute carrier family 25 member 52 [Source:HGNC Symbol;Acc:HGNC:23324]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0051724//NAD transmembrane transporter activity	GO:1990549//mitochondrial NAD transmembrane transport	--
ENSG00000141441	0.426	0.478	0.408	0.306	0.471	0.264	63	71	44	34	58	28	GAREM1	GRB2 associated regulator of MAPK1 subtype 1 [Source:HGNC Symbol;Acc:HGNC:26136]	-	-	-	-	GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0070064//proline-rich region binding	GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0051781//positive regulation of cell division;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus	--
ENSG00000141446	2.223	1.701	1.705	0.899	1.509	1.506	208	160	118	62	120	103	ESCO1	establishment of sister chromatid cohesion N-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24645]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0008080//N-acetyltransferase activity;GO:0008270//zinc ion binding;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061733//peptide-lysine-N-acetyltransferase activity	GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007062//sister chromatid cohesion;GO:0018394//peptidyl-lysine acetylation;GO:0034421//post-translational protein acetylation	--
ENSG00000141447	93.246	88.318	86.527	88.011	85.876	89.854	6017	5812	4184	4111	4597	4421	OSBPL1A	oxysterol binding protein like 1A [Source:HGNC Symbol;Acc:HGNC:16398]	-	-	-	-	GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044232//organelle membrane contact site;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006699//bile acid biosynthetic process;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0015918//sterol transport;GO:0016192//vesicle-mediated transport	--
ENSG00000141448	1.61	1.787	1.009	2.116	2.809	2.712	121	122	56	107	167	135	GATA6	GATA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:4174]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0031965//nuclear membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051525//NFAT protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0001949//sebaceous gland cell differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0003148//outflow tract septum morphogenesis;GO:0003162//atrioventricular node development;GO:0003163//sinoatrial node development;GO:0003309//type B pancreatic cell differentiation;GO:0003310//pancreatic A cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006644//phospholipid metabolic process;GO:0007493//endodermal cell fate determination;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030513//positive regulation of BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0031016//pancreas development;GO:0032526//response to retinoic acid;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0035239//tube morphogenesis;GO:0035987//endodermal cell differentiation;GO:0036302//atrioventricular canal development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043066//negative regulation of apoptotic process;GO:0043627//response to estrogen;GO:0045165//cell fate commitment;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048645//animal organ formation;GO:0048738//cardiac muscle tissue development;GO:0051145//smooth muscle cell differentiation;GO:0051591//response to cAMP;GO:0051891//positive regulation of cardioblast differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060047//heart contraction;GO:0060430//lung saccule development;GO:0060486//club cell differentiation;GO:0060510//type II pneumocyte differentiation;GO:0060575//intestinal epithelial cell differentiation;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0070848//response to growth factor;GO:0071371//cellular response to gonadotropin stimulus;GO:0071456//cellular response to hypoxia;GO:0071773//cellular response to BMP stimulus;GO:0098773//skin epidermis development;GO:0110024//positive regulation of cardiac muscle myoblast proliferation;GO:1901390//positive regulation of transforming growth factor beta activation;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1904003//negative regulation of sebum secreting cell proliferation"	zf-GATA
ENSG00000141449	0.595	0.26	0.107	0.247	0.243	0.147	36	41	13	26	38	20	GREB1L	GREB1 like retinoic acid receptor coactivator [Source:HGNC Symbol;Acc:HGNC:31042]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0003231//cardiac ventricle development;GO:0030539//male genitalia development;GO:0060065//uterus development;GO:0060562//epithelial tube morphogenesis;GO:0061205//paramesonephric duct development;GO:0072177//mesonephric duct development	--
ENSG00000141452	6.271	6.891	6.966	6.765	6.281	7.406	284.18	300	234.19	227	241	242.48	RMC1	regulator of MON1-CCZ1 [Source:HGNC Symbol;Acc:HGNC:24326]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0035658//Mon1-Ccz1 complex	GO:0005515//protein binding	GO:0006914//autophagy;GO:0010506//regulation of autophagy	--
ENSG00000141456	14.521	16.397	17.228	15.813	15.866	14.609	1049	1151	913	850	945	783	PELP1	"proline, glutamate and leucine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:30134]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0035327//transcriptionally active chromatin;GO:0071339//MLL1 complex	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0032183//SUMO binding;GO:0047485//protein N-terminus binding;GO:0051117//ATPase binding	GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071391//cellular response to estrogen stimulus	--
ENSG00000141458	36.257	35.076	36.483	38.891	37.307	49.113	3076.82	2935	2373.81	2249	2570	2934.52	NPC1	NPC intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7897]	Cellular Processes;Organismal Systems	Transport and catabolism;Digestive system	ko04142//Lysosome;ko04979//Cholesterol metabolism	K12385;K12385	GO:0005576//extracellular region;GO:0005635//nuclear envelope;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1905103//integral component of lysosomal membrane	GO:0001618//virus receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0038023//signaling receptor activity	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0007041//lysosomal transport;GO:0007628//adult walking behavior;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008206//bile acid metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010467//gene expression;GO:0016242//negative regulation of macroautophagy;GO:0030301//cholesterol transport;GO:0031579//membrane raft organization;GO:0032367//intracellular cholesterol transport;GO:0033344//cholesterol efflux;GO:0042632//cholesterol homeostasis;GO:0046686//response to cadmium ion;GO:0046718//viral entry into host cell;GO:0060548//negative regulation of cell death;GO:0071383//cellular response to steroid hormone stimulus;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0090150//establishment of protein localization to membrane	--
ENSG00000141469	0	0.063	0	0.023	0.015	0.028	0	2	0	1	1	1	SLC14A1	solute carrier family 14 member 1 (Kidd blood group) [Source:HGNC Symbol;Acc:HGNC:10918]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005372//water transmembrane transporter activity;GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0015265//urea channel activity	GO:0006833//water transport;GO:0015840//urea transport;GO:0055085//transmembrane transport;GO:0071918//urea transmembrane transport	--
ENSG00000141480	5.402	6.658	6.894	8.1	6.625	6.952	176	220	163	192	182	165	ARRB2	arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712]	Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Sensory system;Signal transduction;Transport and catabolism;Cancer: overview;Immune system;Nervous system;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Signal transduction	"ko04740//Olfactory transduction;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction;ko04929//GnRH secretion;ko04340//Hedgehog signaling pathway"	K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439;K04439	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane	GO:0001664//G protein-coupled receptor binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0031691//alpha-1A adrenergic receptor binding;GO:0031692//alpha-1B adrenergic receptor binding;GO:0031701//angiotensin receptor binding;GO:0031702//type 1 angiotensin receptor binding;GO:0031748//D1 dopamine receptor binding;GO:0031762//follicle-stimulating hormone receptor binding;GO:0031826//type 2A serotonin receptor binding;GO:0031859//platelet activating factor receptor binding;GO:0042802//identical protein binding;GO:0043422//protein kinase B binding;GO:0044877//protein-containing complex binding;GO:0051019//mitogen-activated protein kinase binding;GO:0071889//14-3-3 protein binding;GO:1990763//arrestin family protein binding	"GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002031//G protein-coupled receptor internalization;GO:0002032//desensitization of G protein-coupled receptor signaling pathway by arrestin;GO:0002092//positive regulation of receptor internalization;GO:0006366//transcription by RNA polymerase II;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0007420//brain development;GO:0007628//adult walking behavior;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0031623//receptor internalization;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032695//negative regulation of interleukin-12 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051897//positive regulation of protein kinase B signaling;GO:0051898//negative regulation of protein kinase B signaling;GO:0051928//positive regulation of calcium ion transport;GO:0060079//excitatory postsynaptic potential;GO:0060326//cell chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:1904037//positive regulation of epithelial cell apoptotic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:2000727//positive regulation of cardiac muscle cell differentiation"	--
ENSG00000141485	0	0	0	0	0	0	0	0	0	0	0	0	SLC13A5	solute carrier family 13 member 5 [Source:HGNC Symbol;Acc:HGNC:23089]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005343//organic acid:sodium symporter activity;GO:0005515//protein binding;GO:0015137//citrate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006842//tricarboxylic acid transport;GO:0015729//oxaloacetate transport;GO:0015741//fumarate transport;GO:0015742//alpha-ketoglutarate transport;GO:0015744//succinate transport;GO:0015746//citrate transport;GO:0035674//tricarboxylic acid transmembrane transport;GO:0055085//transmembrane transport;GO:0071285//cellular response to lithium ion;GO:0071422//succinate transmembrane transport;GO:0098656//anion transmembrane transport;GO:1903825//organic acid transmembrane transport	--
ENSG00000141497	0.439	0.572	0.728	0.71	0.439	0.586	22	31	29	26	20	23	ZMYND15	zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding	"GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000141499	5.566	5.764	7.211	5.929	5.563	6.892	221	218	210	172	182	196	WRAP53	WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0035861//site of double-strand break"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0051087//chaperone binding;GO:0070034//telomerase RNA binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007004//telomere maintenance via telomerase;GO:0030576//Cajal body organization;GO:0032203//telomere formation via telomerase;GO:0034337//RNA folding;GO:0045739//positive regulation of DNA repair;GO:0051973//positive regulation of telomerase activity;GO:0090666//scaRNA localization to Cajal body;GO:0090671//telomerase RNA localization to Cajal body;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904867//protein localization to Cajal body;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000781//positive regulation of double-strand break repair;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000141503	10.953	12.188	12.615	14.736	14.279	13.003	1078	1233	920	1008	1207	945	MINK1	misshapen like kinase 1 [Source:HGNC Symbol;Acc:HGNC:17565]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001952//regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0022407//regulation of cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048812//neuron projection morphogenesis;GO:0048813//dendrite morphogenesis;GO:1900745//positive regulation of p38MAPK cascade;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000141504	30.792	38.786	35.108	35.838	32.321	35.07	552	697	476	479	495	467	SAT2	spermidine/spermine N1-acetyltransferase family member 2 [Source:HGNC Symbol;Acc:HGNC:23160]	Metabolism;Metabolism;Cellular Processes	Global and overview maps;Amino acid metabolism;Cell growth and death	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko04216//Ferroptosis	K00657;K00657;K00657	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0004145//diamine N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019809//spermidine binding;GO:0042802//identical protein binding	GO:0032918//spermidine acetylation;GO:0032919//spermine acetylation;GO:0032920//putrescine acetylation;GO:0046204//nor-spermidine metabolic process	--
ENSG00000141505	0.218	0.379	0.076	0.138	0.06	0	6	7	1	2	1	0	ASGR1	asialoglycoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:742]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K10063	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004873//asialoglycoprotein receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0031668//cellular response to extracellular stimulus	--
ENSG00000141506	0	0	0	0	0.022	0	0	0	0	0	1	0	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5 [Source:HGNC Symbol;Acc:HGNC:30035]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Immune system;Signal transduction;Endocrine system;Circulatory system;Signal transduction;Immune system;Nervous system;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko04072//Phospholipase D signaling pathway;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04611//Platelet activation;ko04725//Cholinergic synapse;ko05145//Toxoplasmosis	K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0016020//membrane;GO:0034451//centriolar satellite"	GO:0016301//kinase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000141510	13.743	20.363	17.828	12.561	15.663	15.103	717	829	595	480	689	494	TP53	tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cardiovascular disease;Cell growth and death;Endocrine system;Nervous system;Signal transduction;Cancer: specific types;Drug resistance: antineoplastic;Aging;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Transport and catabolism;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death;Cancer: specific types;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04137//Mitophagy - animal;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko04216//Ferroptosis;ko05219//Bladder cancer;ko05216//Thyroid cancer	K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451;K04451	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0016605//PML body;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex;GO:0035861//site of double-strand break	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0001094//TFIID-class transcription factor complex binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002020//protease binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003730//mRNA 3'-UTR binding;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030971//receptor tyrosine kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035033//histone deacetylase regulator activity;GO:0035035//histone acetyltransferase binding;GO:0036310//ATP-dependent DNA/DNA annealing activity;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0051721//protein phosphatase 2A binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0097718//disordered domain specific binding;GO:0140296//general transcription initiation factor binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001836//release of cytochrome c from mitochondria;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002309//T cell proliferation involved in immune response;GO:0002326//B cell lineage commitment;GO:0002360//T cell lineage commitment;GO:0002931//response to ischemia;GO:0006289//nucleotide-excision repair;GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0006979//response to oxidative stress;GO:0006983//ER overload response;GO:0007049//cell cycle;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0007369//gastrulation;GO:0007406//negative regulation of neuroblast proliferation;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0007569//cell aging;GO:0007623//circadian rhythm;GO:0008104//protein localization;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell population proliferation;GO:0008340//determination of adult lifespan;GO:0009299//mRNA transcription;GO:0009303//rRNA transcription;GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0009651//response to salt stress;GO:0009792//embryo development ending in birth or egg hatching;GO:0010165//response to X-ray;GO:0010332//response to gamma radiation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0012501//programmed cell death;GO:0016032//viral process;GO:0021549//cerebellum development;GO:0030308//negative regulation of cell growth;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031065//positive regulation of histone deacetylation;GO:0031497//chromatin assembly;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0033077//T cell differentiation in thymus;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034103//regulation of tissue remodeling;GO:0034613//cellular protein localization;GO:0034644//cellular response to UV;GO:0035264//multicellular organism growth;GO:0035794//positive regulation of mitochondrial membrane permeability;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0042127//regulation of cell population proliferation;GO:0042149//cellular response to glucose starvation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043504//mitochondrial DNA repair;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043523//regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045861//negative regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045899//positive regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0045930//negative regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046677//response to antibiotic;GO:0048147//negative regulation of fibroblast proliferation;GO:0048511//rhythmic process;GO:0048512//circadian behavior;GO:0048539//bone marrow development;GO:0048568//embryonic organ development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050821//protein stabilization;GO:0051097//negative regulation of helicase activity;GO:0051262//protein tetramerization;GO:0051276//chromosome organization;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0051974//negative regulation of telomerase activity;GO:0060218//hematopoietic stem cell differentiation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060411//cardiac septum morphogenesis;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0062100//positive regulation of programmed necrotic cell death;GO:0065003//protein-containing complex assembly;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070243//regulation of thymocyte apoptotic process;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0070266//necroptotic process;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:0071479//cellular response to ionizing radiation;GO:0071480//cellular response to gamma radiation;GO:0071494//cellular response to UV-C;GO:0072331//signal transduction by p53 class mediator;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0072717//cellular response to actinomycin D;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090343//positive regulation of cell aging;GO:0090399//replicative senescence;GO:0090403//oxidative stress-induced premature senescence;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097252//oligodendrocyte apoptotic process;GO:1900119//positive regulation of execution phase of apoptosis;GO:1901525//negative regulation of mitophagy;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902253//regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1902749//regulation of cell cycle G2/M phase transition;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903451//negative regulation of G1 to G0 transition;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:1904024//negative regulation of glucose catabolic process to lactate via pyruvate;GO:1905856//negative regulation of pentose-phosphate shunt;GO:1990144//intrinsic apoptotic signaling pathway in response to hypoxia;GO:1990248//regulation of transcription from RNA polymerase II promoter in response to DNA damage;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:2000269//regulation of fibroblast apoptotic process;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000772//regulation of cellular senescence;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	P53
ENSG00000141519	2.575	2.475	2.841	1.28	1.345	1.153	141	164	119	62	80	59	CCDC40	coiled-coil domain containing 40 [Source:HGNC Symbol;Acc:HGNC:26090]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001947//heart looping;GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0003356//regulation of cilium beat frequency;GO:0030317//flagellated sperm motility;GO:0030324//lung development;GO:0035082//axoneme assembly;GO:0035469//determination of pancreatic left/right asymmetry;GO:0036159//inner dynein arm assembly;GO:0044458//motile cilium assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0070286//axonemal dynein complex assembly;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry	--
ENSG00000141522	84.836	89.199	95.933	106.72	103.438	93.589	3092	3247	2632	2930	3235	2495	ARHGDIA	Rho GDP dissociation inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:678]	Organismal Systems;Organismal Systems	Nervous system;Excretory system	ko04722//Neurotrophin signaling pathway;ko04962//Vasopressin-regulated water reabsorption	K12462;K12462	GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007162//negative regulation of cell adhesion;GO:0007266//Rho protein signal transduction;GO:0032880//regulation of protein localization;GO:0035023//regulation of Rho protein signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0050790//regulation of catalytic activity;GO:0071526//semaphorin-plexin signaling pathway;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000141524	19.191	20.709	19.241	25.971	28.574	22.284	1244.53	1257.27	933.44	964.2	1183.22	969.5	TMC6	transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0008150//biological_process;GO:0034220//ion transmembrane transport	--
ENSG00000141526	260.824	252.853	291.29	396.837	376.64	400.79	13865.99	13672	11578	15874	17027	15631	SLC16A3	solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]	Human Diseases	Cancer: overview	ko05230//Central carbon metabolism in cancer	K08180	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0031965//nuclear membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0035873//lactate transmembrane transport;GO:0035879//plasma membrane lactate transport;GO:0055085//transmembrane transport	--
ENSG00000141527	0.116	0.066	0	0.072	0.091	0.128	10	3	0	4	6	8	CARD14	caspase recruitment domain family member 14 [Source:HGNC Symbol;Acc:HGNC:16446]	Environmental Information Processing	Signal transduction	ko04064//NF-kappa B signaling pathway	K20913	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016235//aggresome	GO:0005515//protein binding;GO:0050700//CARD domain binding	GO:0001934//positive regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000141540	12.594	12.913	9.534	13.316	14.046	12.699	900	928	503	705	837	660	TTYH2	tweety family member 2 [Source:HGNC Symbol;Acc:HGNC:13877]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0072320//volume-sensitive chloride channel activity	GO:0006811//ion transport;GO:0006821//chloride transport	--
ENSG00000141542	0.986	1.024	1.438	1.265	0.896	0.729	46	56	56	45	46	29	RAB40B	"RAB40B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18284]"	-	-	-	-	GO:0005635//nuclear envelope;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0072659//protein localization to plasma membrane;GO:1901998//toxin transport	--
ENSG00000141543	22.08	23.526	22.848	22.38	19.525	20.843	717	767	546	538	539	495	EIF4A3	eukaryotic translation initiation factor 4A3 [Source:HGNC Symbol;Acc:HGNC:18683]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K13025;K13025;K13025	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0035145//exon-exon junction complex;GO:0043025//neuronal cell body;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0098978//glutamatergic synapse;GO:0099524//postsynaptic cytosol;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008143//poly(A) binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035368//selenocysteine insertion sequence binding;GO:0035613//RNA stem-loop binding;GO:0043021//ribonucleoprotein complex binding;GO:0045182//translation regulator activity	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000398//mRNA splicing, via spliceosome;GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0008306//associative learning;GO:0008380//RNA splicing;GO:0010629//negative regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0017148//negative regulation of translation;GO:0035640//exploration behavior;GO:0045727//positive regulation of translation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0051028//mRNA transport;GO:0072715//cellular response to selenite ion;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0099578//regulation of translation at postsynapse, modulating synaptic transmission;GO:1902415//regulation of mRNA binding;GO:1904570//negative regulation of selenocysteine incorporation;GO:1904574//negative regulation of selenocysteine insertion sequence binding;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus;GO:2000622//regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000141551	39.975	42.811	41.52	43.774	42.072	41.303	2182.01	2389	1763	1793	2021	1703	CSNK1D	casein kinase 1 delta [Source:HGNC Symbol;Acc:HGNC:2452]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems	Signal transduction;Cellular community - eukaryotes;Signal transduction;Environmental adaptation	ko04390//Hippo signaling pathway;ko04540//Gap junction;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm	K08959;K08959;K08959;K08959	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0036064//ciliary basal body;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0045296//cadherin binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007020//microtubule nucleation;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032922//circadian regulation of gene expression;GO:0034067//protein localization to Golgi apparatus;GO:0042752//regulation of circadian rhythm;GO:0048208//COPII vesicle coating;GO:0048511//rhythmic process;GO:0051225//spindle assembly;GO:0061512//protein localization to cilium;GO:0071539//protein localization to centrosome;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1905426//positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation;GO:1905515//non-motile cilium assembly;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000052//positive regulation of non-canonical Wnt signaling pathway	--
ENSG00000141552	27.656	26.254	26.476	35.817	25.919	28.266	361	350	262	349	290	270	ANAPC11	anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03358;K03358;K03358;K03358;K03358	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031461//cullin-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0097602//cullin family protein binding	GO:0000278//mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000141556	29.142	25.769	26.813	29.927	28.317	25.436	2143.38	2162.94	1634.85	1764.44	2014.77	1462.85	TBCD	tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0051087//chaperone binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway;GO:0010812//negative regulation of cell-substrate adhesion;GO:0031115//negative regulation of microtubule polymerization;GO:0034333//adherens junction assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0050790//regulation of catalytic activity;GO:0070830//bicellular tight junction assembly	--
ENSG00000141560	10.875	12.162	11.393	11.461	10.022	9.746	411	462	318	298	320	268	FN3KRP	fructosamine 3 kinase related protein [Source:HGNC Symbol;Acc:HGNC:25700]	-	-	-	-	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0102193//protein-ribulosamine 3-kinase activity	GO:0016310//phosphorylation;GO:0043687//post-translational protein modification	--
ENSG00000141562	33.902	33.7	36.395	35.424	33.545	34.939	1219	1217	914	953	1034	964	NARF	nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]	-	-	-	-	GO:0005634//nucleus;GO:0005638//lamin filament;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031981//nuclear lumen	GO:0005521//lamin binding	-	--
ENSG00000141564	8.383	7.878	9.532	8.576	9.139	8.719	1158	1115	977	901	1076	894	RPTOR	regulatory associated protein of MTOR complex 1 [Source:HGNC Symbol;Acc:HGNC:30287]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes	Signal transduction;Infectious disease: bacterial;Environmental adaptation;Cancer: overview;Signal transduction;Transport and catabolism;Endocrine system;Signal transduction;Aging;Aging;Transport and catabolism	ko04151//PI3K-Akt signaling pathway;ko05131//Shigellosis;ko04714//Thermogenesis;ko05206//MicroRNAs in cancer;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04213//Longevity regulating pathway - multiple species;ko04136//Autophagy - other	K07204;K07204;K07204;K07204;K07204;K07204;K07204;K07204;K07204;K07204;K07204	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0030425//dendrite;GO:0031931//TORC1 complex;GO:0043025//neuronal cell body	GO:0001002//RNA polymerase III type 1 promoter sequence-specific DNA binding;GO:0001003//RNA polymerase III type 2 promoter sequence-specific DNA binding;GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0001156//TFIIIC-class transcription factor complex binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0030295//protein kinase activator activity;GO:0030674//protein-macromolecule adaptor activity;GO:0044877//protein-containing complex binding;GO:0071889//14-3-3 protein binding	GO:0001558//regulation of cell growth;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0008361//regulation of cell size;GO:0009267//cellular response to starvation;GO:0009410//response to xenobiotic stimulus;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0016310//phosphorylation;GO:0030307//positive regulation of cell growth;GO:0031669//cellular response to nutrient levels;GO:0031929//TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0032147//activation of protein kinase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035176//social behavior;GO:0038202//TORC1 signaling;GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0045821//positive regulation of glycolytic process;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0046889//positive regulation of lipid biosynthetic process;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:0071456//cellular response to hypoxia;GO:0071470//cellular response to osmotic stress;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1905857//positive regulation of pentose-phosphate shunt	--
ENSG00000141568	15.441	15.37	16.815	12.256	16.804	15.975	1354	1386	1163	921	1227	1061	FOXK2	forkhead box K2 [Source:HGNC Symbol;Acc:HGNC:6036]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	"GO:0000287//magnesium ion binding;GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001678//cellular glucose homeostasis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010507//negative regulation of autophagy;GO:0010906//regulation of glucose metabolic process;GO:0042594//response to starvation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061621//canonical glycolysis"	Fork_head
ENSG00000141569	5.827	6.189	8.038	6.414	7.085	8.64	295	291	271	224	295	279	TRIM65	tripartite motif containing 65 [Source:HGNC Symbol;Acc:HGNC:27316]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0010508//positive regulation of autophagy	--
ENSG00000141570	2.669	2.48	3.334	1.805	1.833	1.234	87	106	94	60	79	60	CBX8	chromobox 8 [Source:HGNC Symbol;Acc:HGNC:15962]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0097027//ubiquitin-protein transferase activator activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0016574//histone ubiquitination;GO:0050790//regulation of catalytic activity	--
ENSG00000141574	0.412	0.549	0.645	1.285	1.609	1.125	9	20	12	37	39	34	SECTM1	secreted and transmembrane 1 [Source:HGNC Symbol;Acc:HGNC:10707]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007498//mesoderm development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000141576	11.326	11.702	12.271	10.695	11.12	9.784	1095	1144	848	755	911	697	RNF157	ring finger protein 157 [Source:HGNC Symbol;Acc:HGNC:29402]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0044297//cell body	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008333//endosome to lysosome transport;GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0051865//protein autoubiquitination;GO:1903861//positive regulation of dendrite extension	--
ENSG00000141577	4.261	3.94	5.855	4.541	4.599	4.151	313	287	257	246	272	211	CEP131	centrosomal protein 131 [Source:HGNC Symbol;Acc:HGNC:29511]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0034451//centriolar satellite;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge;GO:0120212//sperm head-tail coupling apparatus	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding	GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007288//sperm axoneme assembly;GO:0008284//positive regulation of cell population proliferation;GO:0010824//regulation of centrosome duplication;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0035735//intraciliary transport involved in cilium assembly;GO:0042073//intraciliary transport;GO:0060271//cilium assembly;GO:0071539//protein localization to centrosome;GO:0090316//positive regulation of intracellular protein transport;GO:1905198//manchette assembly;GO:1905515//non-motile cilium assembly;GO:1990953//intramanchette transport	--
ENSG00000141579	0.032	0	0	0	0	0	1	0	0	0	0	0	ZNF750	zinc finger protein 750 [Source:HGNC Symbol;Acc:HGNC:25843]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008544//epidermis development;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000141580	21.669	23.189	23.627	22.198	21.48	25.555	1103	1187	895	811	923	948	WDR45B	WD repeat domain 45B [Source:HGNC Symbol;Acc:HGNC:25072]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005764//lysosome;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane;GO:0034045//phagophore assembly site membrane	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0062078//TSC1-TSC2 complex binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0034497//protein localization to phagophore assembly site;GO:0044804//autophagy of nucleus	--
ENSG00000141582	7.82	7.948	7.906	9.67	9.813	10.988	422	431	284	386	446	432	CBX4	chromobox 4 [Source:HGNC Symbol;Acc:HGNC:1554]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0000976//transcription cis-regulatory region binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0019899//enzyme binding;GO:0032183//SUMO binding;GO:0035064//methylated histone binding;GO:0051219//phosphoprotein binding;GO:0061665//SUMO ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0016925//protein sumoylation;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000141622	0.02	0.049	0.027	0.099	0	0	2	5	2	3	0	0	RNF165	ring finger protein 165 [Source:HGNC Symbol;Acc:HGNC:31696]	-	-	-	-	GO:0005634//nucleus;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0007409//axonogenesis;GO:0008045//motor neuron axon guidance;GO:0010259//multicellular organism aging;GO:0030163//protein catabolic process;GO:0030513//positive regulation of BMP signaling pathway;GO:0035136//forelimb morphogenesis;GO:0060173//limb development;GO:0060384//innervation;GO:0061061//muscle structure development	--
ENSG00000141627	25.378	19.028	19.127	20.297	24.321	22.283	1743	1483	1142	1101	1336	1306	DYM	dymeclin [Source:HGNC Symbol;Acc:HGNC:21317]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0007030//Golgi organization;GO:0060348//bone development	--
ENSG00000141639	8.7	7.776	8.932	7.092	7.739	8.11	858	769	650	519	645	583	MAPK4	mitogen-activated protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:6878]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K06855	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000141642	3.441	2.791	3.331	3.115	2.237	2.988	104	107	83	75.87	76	77	ELAC1	elaC ribonuclease Z 1 [Source:HGNC Symbol;Acc:HGNC:14197]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0016787//hydrolase activity;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0042781//3'-tRNA processing endoribonuclease activity;GO:0046872//metal ion binding"	"GO:0008033//tRNA processing;GO:0034414//tRNA 3'-trailer cleavage, endonucleolytic;GO:0042779//tRNA 3'-trailer cleavage;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000141644	18.409	18.075	20.062	19.491	21.902	18.017	1123	1082	875	815	1078	791	MBD1	methyl-CpG binding domain protein 1 [Source:HGNC Symbol;Acc:HGNC:6916]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016363//nuclear matrix;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0010385//double-stranded methylated DNA binding;GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding	"GO:0006366//transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	MBD
ENSG00000141646	17.54	17.292	15.89	12.328	13.062	14.592	1453.43	1301.61	958.52	808.37	920	994	SMAD4	SMAD family member 4 [Source:HGNC Symbol;Acc:HGNC:6770]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Infectious disease: viral;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Signal transduction;Cell growth and death;Immune system;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04659//Th17 cell differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko04520//Adherens junction	K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501;K04501	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0032444//activin responsive factor complex;GO:0032991//protein-containing complex;GO:0071141//SMAD protein complex;GO:0071144//heteromeric SMAD protein complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0031005//filamin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043199//sulfate binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001541//ovarian follicle development;GO:0001649//osteoblast differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001702//gastrulation with mouth forming second;GO:0001822//kidney development;GO:0003148//outflow tract septum morphogenesis;GO:0003161//cardiac conduction system development;GO:0003190//atrioventricular valve formation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003220//left ventricular cardiac muscle tissue morphogenesis;GO:0003251//positive regulation of cell proliferation involved in heart valve morphogenesis;GO:0003279//cardiac septum development;GO:0003360//brainstem development;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006879//cellular iron ion homeostasis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007183//SMAD protein complex assembly;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007369//gastrulation;GO:0007411//axon guidance;GO:0007492//endoderm development;GO:0007498//mesoderm development;GO:0007568//aging;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014033//neural crest cell differentiation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030325//adrenal gland development;GO:0030509//BMP signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032525//somite rostral/caudal axis specification;GO:0032909//regulation of transforming growth factor beta2 production;GO:0033686//positive regulation of luteinizing hormone secretion;GO:0035556//intracellular signal transduction;GO:0036302//atrioventricular canal development;GO:0042060//wound healing;GO:0042118//endothelial cell activation;GO:0042127//regulation of cell population proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0042733//embryonic digit morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0048382//mesendoderm development;GO:0048589//developmental growth;GO:0048663//neuron fate commitment;GO:0048729//tissue morphogenesis;GO:0048733//sebaceous gland development;GO:0048859//formation of anatomical boundary;GO:0051098//regulation of binding;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051797//regulation of hair follicle development;GO:0060065//uterus development;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0060548//negative regulation of cell death;GO:0060956//endocardial cell differentiation;GO:0061040//female gonad morphogenesis;GO:0062009//secondary palate development;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0071559//response to transforming growth factor beta;GO:0071773//cellular response to BMP stimulus;GO:0072133//metanephric mesenchyme morphogenesis;GO:0072134//nephrogenic mesenchyme morphogenesis;GO:0072520//seminiferous tubule development;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090287//regulation of cellular response to growth factor stimulus;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1905305//negative regulation of cardiac myofibril assembly;GO:2000617//positive regulation of histone H3-K9 acetylation"	MH1
ENSG00000141655	0.296	0.306	0.337	0.487	0.198	0.452	32	42	27	31	19	23	TNFRSF11A	TNF receptor superfamily member 11a [Source:HGNC Symbol;Acc:HGNC:11908]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune disease;Development and regeneration;Endocrine system	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway;ko05323//Rheumatoid arthritis;ko04380//Osteoclast differentiation;ko04917//Prolactin signaling pathway	K05147;K05147;K05147;K05147;K05147	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	GO:0001503//ossification;GO:0002250//adaptive immune response;GO:0002548//monocyte chemotaxis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0009314//response to radiation;GO:0030316//osteoclast differentiation;GO:0032496//response to lipopolysaccharide;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034097//response to cytokine;GO:0034612//response to tumor necrosis factor;GO:0043507//positive regulation of JUN kinase activity;GO:0045780//positive regulation of bone resorption;GO:0048535//lymph node development;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060086//circadian temperature homeostasis;GO:0060749//mammary gland alveolus development;GO:0070555//response to interleukin-1;GO:0071812//positive regulation of fever generation by positive regulation of prostaglandin secretion;GO:0071847//TNFSF11-mediated signaling pathway;GO:0071848//positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling;GO:0072674//multinuclear osteoclast differentiation	--
ENSG00000141664	3.711	3.804	4.74	2.547	4.218	3.354	394	409	269	212	305	270	ZCCHC2	zinc finger CCHC-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22916]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	-	--
ENSG00000141665	3.079	3.624	3.57	2.628	2.618	2.582	98	112	74	65	74	60	FBXO15	F-box protein 15 [Source:HGNC Symbol;Acc:HGNC:13617]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000141668	0.347	0.087	0.054	0.054	0.047	0.11	12	5	2	2	2	4	CBLN2	cerebellin 2 precursor [Source:HGNC Symbol;Acc:HGNC:1544]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding	GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0098814//spontaneous synaptic transmission;GO:0099558//maintenance of synapse structure;GO:1905606//regulation of presynapse assembly	--
ENSG00000141682	1.955	1.642	1.066	1.714	1.47	3.951	77	65	31	50	43	105	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1 [Source:HGNC Symbol;Acc:HGNC:9108]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Cancer: overview;Cancer: overview;Cell growth and death;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cell growth and death	ko05200//Pathways in cancer;ko05203//Viral carcinogenesis;ko04210//Apoptosis;ko05210//Colorectal cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04215//Apoptosis - multiple species	K10131;K10131;K10131;K10131;K10131;K10131;K10131	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0097136//Bcl-2 family protein complex	GO:0005515//protein binding	"GO:0001836//release of cytochrome c from mitochondria;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010498//proteasomal protein catabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0042149//cellular response to glucose starvation;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043331//response to dsRNA;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0046902//regulation of mitochondrial membrane permeability;GO:0051607//defense response to virus;GO:0071456//cellular response to hypoxia;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0072593//reactive oxygen species metabolic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097193//intrinsic apoptotic signaling pathway;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000141696	19.993	26.704	20.883	20.925	23.553	20.159	946	1215	732	700	906	701	P3H4	prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:1902494//catalytic complex	GO:0005515//protein binding;GO:0005518//collagen binding	GO:0007130//synaptonemal complex assembly;GO:0017185//peptidyl-lysine hydroxylation;GO:0030199//collagen fibril organization;GO:0032964//collagen biosynthetic process;GO:0046849//bone remodeling	--
ENSG00000141698	31.732	32.001	37.147	36.037	34.159	36.149	772	779	665	677	709	645	NT5C3B	"5'-nucleotidase, cytosolic IIIB [Source:HGNC Symbol;Acc:HGNC:28300]"	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K24242;K24242	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0043928//exonucleolytic catabolism of deadenylated mRNA	--
ENSG00000141699	12.71	13.12	14.658	10.441	12.442	12.37	733	851	689	556	637	593	RETREG3	reticulophagy regulator family member 3 [Source:HGNC Symbol;Acc:HGNC:27258]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0010976//positive regulation of neuron projection development;GO:0061709//reticulophagy	--
ENSG00000141736	32.361	30.557	32.843	33.441	33.009	32.304	2225	2524	1849	1852	2262	1764	ERBB2	erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cellular community - eukaryotes;Cancer: overview;Cancer: specific types;Cancer: specific types;Signal transduction;Cancer: specific types;Drug resistance: antineoplastic;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04530//Tight junction;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko05226//Gastric cancer;ko04066//HIF-1 signaling pathway;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko04520//Adherens junction;ko05213//Endometrial cancer;ko05219//Bladder cancer	K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083;K05083	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0038143//ERBB3:ERBB2 complex;GO:0043209//myelin sheath;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm;GO:0098590//plasma membrane region	GO:0000166//nucleotide binding;GO:0001042//RNA polymerase I core binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0043125//ErbB-3 class receptor binding;GO:0046982//protein heterodimerization activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0007507//heart development;GO:0007528//neuromuscular junction development;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030182//neuron differentiation;GO:0030307//positive regulation of cell growth;GO:0032886//regulation of microtubule-based process;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0033674//positive regulation of kinase activity;GO:0035556//intracellular signal transduction;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042552//myelination;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043547//positive regulation of GTPase activity;GO:0045727//positive regulation of translation;GO:0045765//regulation of angiogenesis;GO:0045785//positive regulation of cell adhesion;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0046777//protein autophosphorylation;GO:0048709//oligodendrocyte differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050896//response to stimulus;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000141738	7.829	7.536	7.085	5.892	6.346	6.282	225	257	158	138	185	154	GRB7	growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0030335//positive regulation of cell migration;GO:0034063//stress granule assembly	--
ENSG00000141741	21.526	20.932	24.435	22.965	22.153	25.973	584	581	479	483	516	489	MIEN1	migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0010269//response to selenium ion;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0051491//positive regulation of filopodium assembly	--
ENSG00000141744	0.176	0.058	0	0.096	0	0.196	3	1	0	1	0	2	PNMT	phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K00553;K00553	GO:0005829//cytosol	GO:0004603//phenylethanolamine N-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation;GO:0042418//epinephrine biosynthetic process;GO:0042423//catecholamine biosynthetic process	--
ENSG00000141748	0	0.051	0	0	0	0	0	1	0	0	0	0	ARL5C	ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111]	-	-	-	-	GO:0005802//trans-Golgi network	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:1903292//protein localization to Golgi membrane	--
ENSG00000141750	0.604	0.909	0.723	0.759	0.948	0.61	43	65	38	40	57	26	STAC2	SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042383//sarcolemma	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0003009//skeletal muscle contraction;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000141753	47.074	46.225	35.969	95.017	90.605	92.134	2153	2125	1215	3219	3501	3066	IGFBP4	insulin like growth factor binding protein 4 [Source:HGNC Symbol;Acc:HGNC:5473]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding	GO:0001558//regulation of cell growth;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0010906//regulation of glucose metabolic process;GO:0040008//regulation of growth;GO:0043410//positive regulation of MAPK cascade;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0044342//type B pancreatic cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000141756	82.109	99.364	76.061	72.866	74.396	61.186	4085	4639	2729	2512	3184	2138	FKBP10	FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169]	-	-	-	-	GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0001701//in utero embryonic development;GO:0017185//peptidyl-lysine hydroxylation;GO:0018208//peptidyl-proline modification;GO:0030199//collagen fibril organization;GO:0035909//aorta morphogenesis;GO:0042060//wound healing;GO:0085029//extracellular matrix assembly	--
ENSG00000141759	36.484	34.558	33.714	44.055	32.494	40.917	844	824	616	738	699	716	TXNL4A	thioredoxin like 4A [Source:HGNC Symbol;Acc:HGNC:30551]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12859	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome	GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0051301//cell division"	--
ENSG00000141837	0	0	0	0	0	0.01	0	0	0	0	0	1	CACNA1A	calcium voltage-gated channel subunit alpha1 A [Source:HGNC Symbol;Acc:HGNC:1388]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Cancer: overview;Nervous system;Neurodegenerative disease;Nervous system;Nervous system;Nervous system;Nervous system;Substance dependence;Nervous system;Sensory system;Nervous system;Nervous system;Endocrine and metabolic disease;Substance dependence	ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko04721//Synaptic vesicle cycle;ko04730//Long-term depression;ko04930//Type II diabetes mellitus;ko05033//Nicotine addiction	K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344;K04344	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0001540//amyloid-beta binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity;GO:0019905//syntaxin binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0008219//cell death;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0050804//modulation of chemical synaptic transmission;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport;GO:1904645//response to amyloid-beta;GO:1904646//cellular response to amyloid-beta	--
ENSG00000141854	0.823	0.976	1.457	1.068	0.941	1.523	26	31	34	25	23	35	MISP3	MISP family member 3 [Source:HGNC Symbol;Acc:HGNC:26963]	-	-	-	-	-	-	-	--
ENSG00000141858	11.921	13.509	12.871	13.609	15.011	11.638	407	446	314	297	393	294	SAMD1	sterile alpha motif domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17958]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000141867	15.796	14.603	14.355	10.708	13.547	12.749	1445	1391	1004	800	1051	892	BRD4	bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]	-	-	-	-	GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0019899//enzyme binding;GO:0031493//nucleosomal histone binding;GO:0070577//lysine-acetylated histone binding;GO:0099122//RNA polymerase II C-terminal domain binding;GO:0106140//P-TEFb complex binding	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043922//negative regulation by host of viral transcription;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:1901407//regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:2000002//negative regulation of DNA damage checkpoint;GO:2001255//positive regulation of histone H3-K36 trimethylation"	--
ENSG00000141873	18.425	24.159	27.562	31.457	23.467	22.691	530.95	672.25	555.46	653.11	576.23	464.27	SLC39A3	solute carrier family 39 member 3 [Source:HGNC Symbol;Acc:HGNC:17128]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14709;K14709	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0046873//metal ion transmembrane transporter activity	GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0030001//metal ion transport;GO:0043029//T cell homeostasis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0055085//transmembrane transport;GO:0060173//limb development;GO:0071577//zinc ion transmembrane transport	--
ENSG00000141905	17.828	17.362	15.16	16.339	18.533	16.78	1398	1304	885	971	1191	1027	NFIC	nuclear factor I C [Source:HGNC Symbol;Acc:HGNC:7786]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	CTF/NFI
ENSG00000141933	10.776	8.138	8.848	13.496	12.653	11.242	249	189	151	231	247	189	TPGS1	tubulin polyglutamylase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:25058]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0030424//axon;GO:0030425//dendrite;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0045202//synapse	GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0007268//chemical synaptic transmission;GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0018095//protein polyglutamylation;GO:0030154//cell differentiation;GO:0030534//adult behavior;GO:0051648//vesicle localization	--
ENSG00000141934	20.55	25.694	25.141	24.961	28.03	30.449	527	657	487	490	614	580	PLPP2	phospholipid phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:9230]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Immune system;Cancer: overview;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism;ko04975//Fat digestion and absorption	K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080	GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0106235//ceramide-1-phosphate phosphatase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0006672//ceramide metabolic process;GO:0007165//signal transduction;GO:0016311//dephosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0046839//phospholipid dephosphorylation	--
ENSG00000141946	0	0	0	0	0	0	0	0	0	0	0	0	ZIM3	zinc finger imprinted 3 [Source:HGNC Symbol;Acc:HGNC:16366]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000141956	1.664	1.081	1.09	1.137	0.891	1.237	130	147	109	114	102	122	PRDM15	PR/SET domain 15 [Source:HGNC Symbol;Acc:HGNC:13999]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032259//methylation;GO:0043409//negative regulation of MAPK cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000035//regulation of stem cell division	zf-C2H2
ENSG00000141959	166.162	170.669	189.995	228.677	224.019	203.859	10041	10385	8479	10240	11439	8970	PFKL	"phosphofructokinase, liver type [Source:HGNC Symbol;Acc:HGNC:8876]"	Metabolism;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Metabolism;Organismal Systems;Genetic Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	"Global and overview maps;Endocrine system;Signal transduction;Signal transduction;Global and overview maps;Endocrine system;Folding, sorting and degradation;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00030//Pentose phosphate pathway	K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005945//6-phosphofructokinase complex;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003872//6-phosphofructokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048029//monosaccharide binding;GO:0070061//fructose binding;GO:0070095//fructose-6-phosphate binding	"GO:0005975//carbohydrate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0009749//response to glucose;GO:0016310//phosphorylation;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0046676//negative regulation of insulin secretion;GO:0061615//glycolytic process through fructose-6-phosphate;GO:0061621//canonical glycolysis"	--
ENSG00000141965	4.225	4.138	4.935	4.4	4.444	5.015	836	823	721.3	645	743	722	FEM1A	fem-1 homolog A [Source:HGNC Symbol;Acc:HGNC:16934]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0031867//EP4 subtype prostaglandin E2 receptor binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0051438//regulation of ubiquitin-protein transferase activity;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000141968	0	0	0	0	0	0	0	0	0	0	0	0	VAV1	vav guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:12657]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system	ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway	K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction	GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140031//phosphorylation-dependent protein binding	GO:0006909//phagocytosis;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0008361//regulation of cell size;GO:0030168//platelet activation;GO:0030217//T cell differentiation;GO:0030593//neutrophil chemotaxis;GO:0031295//T cell costimulation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042110//T cell activation;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0045785//positive regulation of cell adhesion;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0072593//reactive oxygen species metabolic process	--
ENSG00000141971	20.634	22.392	23.976	26.83	26.434	21.889	528	576	446	509	559	400	MVB12A	multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12186	GO:0000813//ESCRT I complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0017124//SH3 domain binding;GO:0043130//ubiquitin binding	GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0019075//virus maturation;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0032801//receptor catabolic process;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046755//viral budding	--
ENSG00000141977	0	0	0	0	0	0	0	0	0	0	0	0	CIB3	calcium and integrin binding family member 3 [Source:HGNC Symbol;Acc:HGNC:24580]	-	-	-	-	-	GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000141979	0	0	0	0	0	0	0	0	0	0	0	0	MED26	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0016592//mediator complex	-	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000141985	34.7	34.112	34.628	40.877	34.996	39.091	1806	1787	1330	1573	1543	1482	SH3GL1	"SH3 domain containing GRB2 like 1, endophilin A2 [Source:HGNC Symbol;Acc:HGNC:10830]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K11247	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0016191//synaptic vesicle uncoating	--
ENSG00000141994	3.915	4.134	4.092	6.319	5.61	5.762	141	148	121	164	163	135	DUS3L	dihydrouridine synthase 3 like [Source:HGNC Symbol;Acc:HGNC:26920]	-	-	-	-	-	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0017150//tRNA dihydrouridine synthase activity;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding	GO:0002943//tRNA dihydrouridine synthesis;GO:0008033//tRNA processing	--
ENSG00000142002	11.762	12.56	12.439	11.547	17.245	18.723	900	922	717	715	866	739	DPP9	dipeptidyl peptidase 9 [Source:HGNC Symbol;Acc:HGNC:18648]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0031252//cell leading edge	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis	--
ENSG00000142025	0	0	0	0	0	0	0	0	0	0	0	0	DMRTC2	DMRT like family C2 [Source:HGNC Symbol;Acc:HGNC:13911]	-	-	-	-	GO:0000785//chromatin;GO:0001741//XY body;GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007141//male meiosis I;GO:0007281//germ cell development;GO:0007290//spermatid nucleus elongation;GO:0007548//sex differentiation;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:1900111//positive regulation of histone H3-K9 dimethylation;GO:1900114//positive regulation of histone H3-K9 trimethylation"	DM
ENSG00000142039	15.216	10.738	13.491	15.844	13.728	14.639	797	720	574	697	717	687	CCDC97	coiled-coil domain containing 97 [Source:HGNC Symbol;Acc:HGNC:28289]	-	-	-	-	-	-	-	--
ENSG00000142046	15.865	18.214	11.108	12.596	14.798	8.202	246.02	287.23	136.9	150.67	184.37	89.84	TMEM91	transmembrane protein 91 [Source:HGNC Symbol;Acc:HGNC:32393]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0008150//biological_process	--
ENSG00000142065	1.478	1.05	1.124	1.613	0.879	1.141	209	164	129	89	94	129	ZFP14	ZFP14 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29312]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0001835//blastocyst hatching;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000142082	10.031	9.893	11.736	11.518	14.217	10.487	407	421	332	306	419	288	SIRT3	sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05230//Central carbon metabolism in cancer;ko00760//Nicotinate and nicotinamide metabolism	K11413;K11413;K11413	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0032991//protein-containing complex	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051287//NAD binding;GO:0070403//NAD+ binding	GO:0006471//protein ADP-ribosylation;GO:0006476//protein deacetylation;GO:0009060//aerobic respiration;GO:0016575//histone deacetylation;GO:0034983//peptidyl-lysine deacetylation;GO:1901671//positive regulation of superoxide dismutase activity;GO:1902553//positive regulation of catalase activity;GO:2000304//positive regulation of ceramide biosynthetic process	--
ENSG00000142089	389.032	392.019	413.7	511.752	455.904	462.753	4890.16	4991.12	3870.3	4800.95	4879.91	4264.47	IFITM3	interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0002376//immune system process;GO:0006955//immune response;GO:0009615//response to virus;GO:0032897//negative regulation of viral transcription;GO:0034341//response to interferon-gamma;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway	--
ENSG00000142102	2.607	2.122	2.208	1.78	1.882	2.448	136	135	113	95	113	123	PGGHG	protein-glucosylgalactosylhydroxylysine glucosidase [Source:HGNC Symbol;Acc:HGNC:26210]	-	-	-	-	GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0047402//protein-glucosylgalactosylhydroxylysine glucosidase activity"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000142149	1.404	0.525	0.578	1.102	2.103	1.096	131	84	68	130	133	127	HUNK	hormonally up-regulated Neu-associated kinase [Source:HGNC Symbol;Acc:HGNC:13326]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000142156	64.729	71.234	73.508	82.351	84.699	71.967	5643	6242	4710	5299	6218	4541	COL6A1	collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K06238;K06238;K06238;K06238;K06238	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005589//collagen type VI trimer;GO:0005615//extracellular space;GO:0005765//lysosomal membrane;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005518//collagen binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0048407//platelet-derived growth factor binding	GO:0001649//osteoblast differentiation;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000142166	22.289	18.017	16.698	13.917	14.26	15.824	1765	1545	1036	844	1026	891	IFNAR1	interferon alpha and beta receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:5432]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04620//Toll-like receptor signaling pathway	K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130;K05130	GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004904//interferon receptor activity;GO:0004905//type I interferon receptor activity;GO:0005515//protein binding;GO:0019962//type I interferon binding	GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0035457//cellular response to interferon-alpha;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus;GO:1901857//positive regulation of cellular respiration	--
ENSG00000142168	198.124	188.804	218.155	213.366	182.862	211.367	3678	3523	2991	2934	2868	2855	SOD1	superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Transport and catabolism;Aging	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04146//Peroxisome;ko04213//Longevity regulating pathway - multiple species	K04565;K04565;K04565;K04565;K04565;K04565;K04565;K04565	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005764//lysosome;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0032839//dendrite cytoplasm;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome;GO:1904115//axon cytoplasm	GO:0004784//superoxide dismutase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0030346//protein phosphatase 2B binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0000302//response to reactive oxygen species;GO:0000303//response to superoxide;GO:0001541//ovarian follicle development;GO:0001819//positive regulation of cytokine production;GO:0001890//placenta development;GO:0001895//retina homeostasis;GO:0001975//response to amphetamine;GO:0002262//myeloid cell homeostasis;GO:0006749//glutathione metabolic process;GO:0006801//superoxide metabolic process;GO:0006879//cellular iron ion homeostasis;GO:0006979//response to oxidative stress;GO:0007283//spermatogenesis;GO:0007566//embryo implantation;GO:0007568//aging;GO:0007569//cell aging;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0008089//anterograde axonal transport;GO:0008090//retrograde axonal transport;GO:0008217//regulation of blood pressure;GO:0009408//response to heat;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0019226//transmission of nerve impulse;GO:0019430//removal of superoxide radicals;GO:0031667//response to nutrient levels;GO:0032287//peripheral nervous system myelin maintenance;GO:0032930//positive regulation of superoxide anion generation;GO:0033081//regulation of T cell differentiation in thymus;GO:0034465//response to carbon monoxide;GO:0034599//cellular response to oxidative stress;GO:0035865//cellular response to potassium ion;GO:0040014//regulation of multicellular organism growth;GO:0042542//response to hydrogen peroxide;GO:0042554//superoxide anion generation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043087//regulation of GTPase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0045471//response to ethanol;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0045859//regulation of protein kinase activity;GO:0046620//regulation of organ growth;GO:0046677//response to antibiotic;GO:0046688//response to copper ion;GO:0046716//muscle cell cellular homeostasis;GO:0048538//thymus development;GO:0048678//response to axon injury;GO:0050665//hydrogen peroxide biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0051881//regulation of mitochondrial membrane potential;GO:0060047//heart contraction;GO:0060052//neurofilament cytoskeleton organization;GO:0060087//relaxation of vascular associated smooth muscle;GO:0060088//auditory receptor cell stereocilium organization;GO:0071276//cellular response to cadmium ion;GO:0071318//cellular response to ATP;GO:0072593//reactive oxygen species metabolic process;GO:0097332//response to antipsychotic drug;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000142173	63.456	66.828	67.278	62.256	65.235	57.527	4480	4733	3490	3254	3901	2957	COL6A2	collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K06238;K06238;K06238;K06238;K06238	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0009749//response to glucose	--
ENSG00000142178	0.07	0	0	0	0.042	0.094	6.9	0	0	0	3.52	6.77	SIK1	salt inducible kinase 1 [Source:HGNC Symbol;Acc:HGNC:11142]	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K19008	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008140//cAMP response element binding protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	GO:0002028//regulation of sodium ion transport;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0010830//regulation of myotube differentiation;GO:0010868//negative regulation of triglyceride biosynthetic process;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0032792//negative regulation of CREB transcription factor activity;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045595//regulation of cell differentiation;GO:0045721//negative regulation of gluconeogenesis;GO:0046777//protein autophosphorylation;GO:0048511//rhythmic process;GO:0055007//cardiac muscle cell differentiation;GO:2000210//positive regulation of anoikis	--
ENSG00000142182	0	0	0	0	0	0	0	0	0	0	0	0	DNMT3L	DNA methyltransferase 3 like [Source:HGNC Symbol;Acc:HGNC:2980]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035098//ESC/E(Z) complex;GO:1902494//catalytic complex	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding	"GO:0006306//DNA methylation;GO:0006349//regulation of gene expression by genetic imprinting;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0032776//DNA methylation on cytosine;GO:0043046//DNA methylation involved in gamete generation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048863//stem cell differentiation;GO:0050790//regulation of catalytic activity;GO:0090116//C-5 methylation of cytosine;GO:1905642//negative regulation of DNA methylation;GO:1905643//positive regulation of DNA methylation"	--
ENSG00000142185	0	0.037	0.013	0.012	0.022	0.013	0	4	1	1	2	1	TRPM2	transient receptor potential cation channel subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:12339]	Organismal Systems;Organismal Systems	Immune system;Endocrine system	ko04621//NOD-like receptor signaling pathway;ko04921//Oxytocin signaling pathway	K04977;K04977	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005272//sodium channel activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0015278//calcium-release channel activity;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity;GO:0072571//mono-ADP-D-ribose binding;GO:0099604//ligand-gated calcium channel activity	GO:0001659//temperature homeostasis;GO:0002407//dendritic cell chemotaxis;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0006979//response to oxidative stress;GO:0009408//response to heat;GO:0014074//response to purine-containing compound;GO:0032024//positive regulation of insulin secretion;GO:0033194//response to hydroperoxide;GO:0034220//ion transmembrane transport;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0035725//sodium ion transmembrane transport;GO:0044849//estrous cycle;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0051489//regulation of filopodium assembly;GO:0055085//transmembrane transport;GO:0070301//cellular response to hydrogen peroxide;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071415//cellular response to purine-containing compound;GO:0071421//manganese ion transmembrane transport;GO:0071502//cellular response to temperature stimulus;GO:0071577//zinc ion transmembrane transport;GO:0097028//dendritic cell differentiation;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098703//calcium ion import across plasma membrane;GO:1903223//positive regulation of oxidative stress-induced neuron death;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000142186	41.063	47.823	48.452	49.591	48.181	42.065	2205	2558.93	1874	1983	2160.5	1650	SCYL1	SCY1 like pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:14372]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030126//COPI vesicle coat	GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0045296//cadherin binding	"GO:0006468//protein phosphorylation;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006954//inflammatory response;GO:0016192//vesicle-mediated transport;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021522//spinal cord motor neuron differentiation;GO:0034613//cellular protein localization;GO:0048666//neuron development"	--
ENSG00000142188	16.422	13.758	16.947	19.078	15.795	17.136	811	674	606	696	654	610	TMEM50B	transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway	--
ENSG00000142192	914.087	946.913	900.818	823.713	916.613	921.662	61258	63361	44888	41173	51757	45196	APP	amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620]	Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04726//Serotonergic synapse	K04520;K04520;K04520	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005790//smooth endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005798//Golgi-associated vesicle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0005911//cell-cell junction;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030424//axon;GO:0030426//growth cone;GO:0031093//platelet alpha granule lumen;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0031904//endosome lumen;GO:0032588//trans-Golgi network membrane;GO:0035253//ciliary rootlet;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0043235//receptor complex;GO:0044304//main axon;GO:0045121//membrane raft;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0048786//presynaptic active zone;GO:0051233//spindle midzone;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0097449//astrocyte projection;GO:1990761//growth cone lamellipodium;GO:1990812//growth cone filopodium	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016504//peptidase activator activity;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity;GO:0030546//signaling receptor activator activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0051425//PTB domain binding;GO:0070851//growth factor receptor binding	GO:0001774//microglial cell activation;GO:0001934//positive regulation of protein phosphorylation;GO:0001967//suckling behavior;GO:0002265//astrocyte activation involved in immune response;GO:0006378//mRNA polyadenylation;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006878//cellular copper ion homeostasis;GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0007155//cell adhesion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0007612//learning;GO:0007617//mating behavior;GO:0007626//locomotory behavior;GO:0008088//axo-dendritic transport;GO:0008203//cholesterol metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0008344//adult locomotory behavior;GO:0008542//visual learning;GO:0009314//response to radiation;GO:0010288//response to lead ion;GO:0010466//negative regulation of peptidase activity;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010951//negative regulation of endopeptidase activity;GO:0010952//positive regulation of peptidase activity;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014005//microglia development;GO:0016199//axon midline choice point recognition;GO:0016322//neuron remodeling;GO:0016358//dendrite development;GO:0030111//regulation of Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0030900//forebrain development;GO:0031175//neuron projection development;GO:0032092//positive regulation of protein binding;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0042327//positive regulation of phosphorylation;GO:0043393//regulation of protein binding;GO:0045665//negative regulation of neuron differentiation;GO:0045821//positive regulation of glycolytic process;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048143//astrocyte activation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048669//collateral sprouting in absence of injury;GO:0050729//positive regulation of inflammatory response;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050803//regulation of synapse structure or activity;GO:0050808//synapse organization;GO:0050885//neuromuscular process controlling balance;GO:0050890//cognition;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051124//synaptic assembly at neuromuscular junction;GO:0051247//positive regulation of protein metabolic process;GO:0051402//neuron apoptotic process;GO:0051563//smooth endoplasmic reticulum calcium ion homeostasis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070555//response to interleukin-1;GO:0071280//cellular response to copper ion;GO:0071287//cellular response to manganese ion;GO:0071320//cellular response to cAMP;GO:0071874//cellular response to norepinephrine stimulus;GO:0090647//modulation of age-related behavioral decline;GO:0098815//modulation of excitatory postsynaptic potential;GO:0150003//regulation of spontaneous synaptic transmission;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904646//cellular response to amyloid-beta;GO:1905606//regulation of presynapse assembly;GO:1905908//positive regulation of amyloid fibril formation;GO:1990000//amyloid fibril formation;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990535//neuron projection maintenance;GO:2000310//regulation of NMDA receptor activity;GO:2000406//positive regulation of T cell migration	--
ENSG00000142197	1.327	1.425	1.181	0.82	1.103	0.906	210	227	139	97	148	105	DOP1B	DOP1 leucine zipper like protein B [Source:HGNC Symbol;Acc:HGNC:1291]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006895//Golgi to endosome transport;GO:0007029//endoplasmic reticulum organization;GO:0009880//embryonic pattern specification;GO:0015031//protein transport;GO:0050890//cognition	--
ENSG00000142207	3.904	4.119	3.639	3.694	4.056	3.657	876	929	603	614	769	597	URB1	URB1 ribosome biogenesis homolog [Source:HGNC Symbol;Acc:HGNC:17344]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0008150//biological_process"	--
ENSG00000142208	57.986	60.026	61.662	71.771	62.667	63.716	3132	3358	2474	2747	2895	2485	AKT1	AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Circulatory system;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Cell growth and death;Signal transduction;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Endocrine system;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Digestive system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04973//Carbohydrate digestion and absorption"	K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456;K04456	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005819//spindle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0036064//ciliary basal body;GO:0098794//postsynapse	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0071889//14-3-3 protein binding;GO:0099104//potassium channel activator activity;GO:0106310//protein serine kinase activity"	"GO:0001649//osteoblast differentiation;GO:0001893//maternal placenta development;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0006006//glucose metabolic process;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006606//protein import into nucleus;GO:0006809//nitric oxide biosynthetic process;GO:0006915//apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007281//germ cell development;GO:0007399//nervous system development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0008637//apoptotic mitochondrial changes;GO:0008643//carbohydrate transport;GO:0009408//response to heat;GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010467//gene expression;GO:0010507//negative regulation of autophagy;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010748//negative regulation of long-chain fatty acid import across plasma membrane;GO:0010761//fibroblast migration;GO:0010763//positive regulation of fibroblast migration;GO:0010765//positive regulation of sodium ion transport;GO:0010907//positive regulation of glucose metabolic process;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0010951//negative regulation of endopeptidase activity;GO:0010975//regulation of neuron projection development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016567//protein ubiquitination;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030163//protein catabolic process;GO:0030307//positive regulation of cell growth;GO:0030334//regulation of cell migration;GO:0031295//T cell costimulation;GO:0031397//negative regulation of protein ubiquitination;GO:0031641//regulation of myelination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0031929//TOR signaling;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0032091//negative regulation of protein binding;GO:0032094//response to food;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032287//peripheral nervous system myelin maintenance;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0032880//regulation of protein localization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034405//response to fluid shear stress;GO:0034614//cellular response to reactive oxygen species;GO:0035556//intracellular signal transduction;GO:0035655//interleukin-18-mediated signaling pathway;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036294//cellular response to decreased oxygen levels;GO:0038061//NIK/NF-kappaB signaling;GO:0042593//glucose homeostasis;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043276//anoikis;GO:0043488//regulation of mRNA stability;GO:0043491//protein kinase B signaling;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045600//positive regulation of fat cell differentiation;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045746//negative regulation of Notch signaling pathway;GO:0045861//negative regulation of proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0046622//positive regulation of organ growth;GO:0046777//protein autophosphorylation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0048266//behavioral response to pain;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051146//striated muscle cell differentiation;GO:0060079//excitatory postsynaptic potential;GO:0060416//response to growth hormone;GO:0060644//mammary gland epithelial cell differentiation;GO:0060709//glycogen cell differentiation involved in embryonic placenta development;GO:0060716//labyrinthine layer blood vessel development;GO:0070141//response to UV-A;GO:0070848//response to growth factor;GO:0071276//cellular response to cadmium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0072655//establishment of protein localization to mitochondrion;GO:0072656//maintenance of protein location in mitochondrion;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0097194//execution phase of apoptosis;GO:0100002//negative regulation of protein kinase activity by protein phosphorylation;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1900182//positive regulation of protein localization to nucleus;GO:1901215//negative regulation of neuron death;GO:1901653//cellular response to peptide;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990418//response to insulin-like growth factor stimulus;GO:2000010//positive regulation of protein localization to cell surface;GO:2000074//regulation of type B pancreatic cell development;GO:2000402//negative regulation of lymphocyte migration;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000142224	0	0	0	0	0	0	0	0	0	0	0	0	IL19	interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5990]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05444;K05444;K05444	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity	GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0072593//reactive oxygen species metabolic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000142227	42.218	44.72	51.405	47.757	37.235	53.356	572	608	471.96	457	426	525	EMP3	epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008219//cell death;GO:0032060//bleb assembly	--
ENSG00000142230	46.797	50.363	53.467	53.245	47.017	48.744	1850	1998	1356	1603	1642	1381	SAE1	SUMO1 activating enzyme subunit 1 [Source:HGNC Symbol;Acc:HGNC:30660]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10684	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031510//SUMO activating enzyme complex	GO:0004839//ubiquitin activating enzyme activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008047//enzyme activator activity;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016874//ligase activity;GO:0019948//SUMO activating enzyme activity;GO:0043008//ATP-dependent protein binding;GO:0044388//small protein activating enzyme binding;GO:0046982//protein heterodimerization activity	GO:0006464//cellular protein modification process;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0032446//protein modification by small protein conjugation;GO:0033235//positive regulation of protein sumoylation;GO:0050790//regulation of catalytic activity;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000142233	0.104	0.13	0.212	0.31	0.155	0.287	4	5	6	4	5	8	NTN5	netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016358//dendrite development;GO:0022008//neurogenesis	--
ENSG00000142235	5.316	4.333	5.458	3.584	4.547	5.174	280	249	229	138	202	221	LMTK3	lemur tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:19295]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation	--
ENSG00000142252	9.245	10.758	11.978	10.47	9.625	10.981	154	189	148	134	135	133	GEMIN7	gem nuclear organelle associated protein 7 [Source:HGNC Symbol;Acc:HGNC:20045]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies;GO:0120114//Sm-like protein family complex	GO:0005515//protein binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000142273	0	0	0	0	0	0	0	0	0	0	0	0	CBLC	Cbl proto-oncogene C [Source:HGNC Symbol;Acc:HGNC:15961]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04144//Endocytosis;ko04120//Ubiquitin mediated proteolysis	K22518;K22518	GO:0005886//plasma membrane;GO:0045121//membrane raft	GO:0001784//phosphotyrosine residue binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005154//epidermal growth factor receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding;GO:0047690//aspartyltransferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0016567//protein ubiquitination;GO:0023051//regulation of signaling;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity	--
ENSG00000142279	7.617	9.447	9.944	12.357	13.817	12.324	405	477	360	513	513	503	WTIP	WT1 interacting protein [Source:HGNC Symbol;Acc:HGNC:20964]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16682;K16682	GO:0000932//P-body;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0030054//cell junction	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001666//response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0030030//cell projection organization;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0035331//negative regulation of hippo signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000637//positive regulation of gene silencing by miRNA"	--
ENSG00000142303	3.139	4.637	3.476	2.178	3.125	2.365	207	271	175	121	214	139	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif 10 [Source:HGNC Symbol;Acc:HGNC:13201]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0003674//molecular_function;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008150//biological_process;GO:0030198//extracellular matrix organization	--
ENSG00000142319	0	0.024	0	0.017	0	0.034	0	2	0	1	0	2	SLC6A3	solute carrier family 6 member 3 [Source:HGNC Symbol;Acc:HGNC:11049]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Substance dependence;Nervous system;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04721//Synaptic vesicle cycle;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K05036;K05036;K05036;K05036;K05036;K05036;K05036	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016600//flotillin complex;GO:0030424//axon;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045121//membrane raft;GO:0098691//dopaminergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005330//dopamine:sodium symporter activity;GO:0005334//norepinephrine:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0015293//symporter activity;GO:0035240//dopamine binding;GO:0043176//amine binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051721//protein phosphatase 2A binding	GO:0001504//neurotransmitter uptake;GO:0006836//neurotransmitter transport;GO:0007568//aging;GO:0007595//lactation;GO:0007608//sensory perception of smell;GO:0007626//locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0010039//response to iron ion;GO:0014070//response to organic cyclic compound;GO:0015844//monoamine transport;GO:0015872//dopamine transport;GO:0015874//norepinephrine transport;GO:0021984//adenohypophysis development;GO:0035094//response to nicotine;GO:0035725//sodium ion transmembrane transport;GO:0040018//positive regulation of multicellular organism growth;GO:0042053//regulation of dopamine metabolic process;GO:0042220//response to cocaine;GO:0042416//dopamine biosynthetic process;GO:0042420//dopamine catabolic process;GO:0045471//response to ethanol;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051591//response to cAMP;GO:0051620//norepinephrine uptake;GO:0060134//prepulse inhibition;GO:0090494//dopamine uptake;GO:1990384//hyaloid vascular plexus regression	--
ENSG00000142327	12.767	12.839	15.032	17.812	15.732	14.159	854	809	715	797	865	677	RNPEPL1	arginyl aminopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:10079]	-	-	-	-	-	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis	--
ENSG00000142330	4.559	6.32	7.14	7.929	6.842	8.372	246	336	286	310	278	303	CAPN10	calpain 10 [Source:HGNC Symbol;Acc:HGNC:1477]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000149//SNARE binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0031532//actin cytoskeleton reorganization;GO:0032024//positive regulation of insulin secretion;GO:0032388//positive regulation of intracellular transport;GO:0032869//cellular response to insulin stimulus;GO:0046326//positive regulation of glucose import;GO:0097050//type B pancreatic cell apoptotic process;GO:2000676//positive regulation of type B pancreatic cell apoptotic process	--
ENSG00000142347	0	0.011	0	0	0.014	0	0	1	0	0	1	0	MYO1F	myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0016461//unconventional myosin complex;GO:0031982//vesicle	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0008150//biological_process;GO:0030050//vesicle transport along actin filament	--
ENSG00000142396	16.89	17.942	20.289	18.757	16.566	23.511	454.4	455.66	402.74	390.39	373.21	472.85	ERVK3-1	endogenous retrovirus group K3 member 1 [Source:HGNC Symbol;Acc:HGNC:30466]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K03178;K03178;K03178	-	GO:0005515//protein binding	-	--
ENSG00000142405	0.015	0	0.02	0	0	0	1	0	1	0	0	0	NLRP12	NLR family pyrin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:22938]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20865	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process	GO:0001818//negative regulation of cytokine production;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0009968//negative regulation of signal transduction;GO:0031953//negative regulation of protein autophosphorylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032661//regulation of interleukin-18 production;GO:0032692//negative regulation of interleukin-1 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0036336//dendritic cell migration;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045751//negative regulation of Toll signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071345//cellular response to cytokine stimulus;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000142408	0.076	0.06	0.015	0.037	0.039	0.022	14	11	2	5	6	3	CACNG8	calcium voltage-gated channel auxiliary subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:13628]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04873;K04873;K04873;K04873;K04873;K04873;K04873	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity	"GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0019226//transmission of nerve impulse;GO:0034765//regulation of ion transmembrane transport;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099590//neurotransmitter receptor internalization;GO:2000311//regulation of AMPA receptor activity"	--
ENSG00000142409	6.983	8.406	9.287	10.44	10.482	10.007	281	340	276	311	356	293	ZNF787	zinc finger protein 787 [Source:HGNC Symbol;Acc:HGNC:26998]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000142444	4.202	5.675	4.747	4.445	5.706	5.401	115	154	95	92	133	108	TIMM29	translocase of inner mitochondrial membrane 29 [Source:HGNC Symbol;Acc:HGNC:25152]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0005515//protein binding;GO:0140318//protein transporter activity	GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000142449	0.635	0.728	0.944	1.108	0.823	0.879	120	138	112	136	131	115	FBN3	fibrillin 3 [Source:HGNC Symbol;Acc:HGNC:18794]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding	GO:0009653//anatomical structure morphogenesis	--
ENSG00000142453	20.796	21.425	23.433	24.42	29.638	22.827	1017.2	1082.45	898.69	990.75	1082.81	825.43	CARM1	coactivator associated arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23393]	Human Diseases	Drug resistance: antineoplastic	ko01522//Endocrine resistance	K05931	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000976//transcription cis-regulatory region binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0030374//nuclear receptor coactivator activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0035642//histone methyltransferase activity (H3-R17 specific);GO:0042054//histone methyltransferase activity;GO:0070577//lysine-acetylated histone binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006479//protein methylation;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0032259//methylation;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034970//histone H3-R2 methylation;GO:0034971//histone H3-R17 methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0045600//positive regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051591//response to cAMP;GO:1902415//regulation of mRNA binding;GO:2000171//negative regulation of dendrite development"	--
ENSG00000142459	10.446	12.049	12.115	12.969	13.043	12.579	838	870	719	771	884	735	EVI5L	ecotropic viral integration site 5 like [Source:HGNC Symbol;Acc:HGNC:30464]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0090630//activation of GTPase activity;GO:1902018//negative regulation of cilium assembly	--
ENSG00000142484	0	0	0	0	0	0	0	0	0	0	0	0	TM4SF5	transmembrane 4 L six family member 5 [Source:HGNC Symbol;Acc:HGNC:11857]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0034618//arginine binding	GO:0007049//cell cycle;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000142494	14.709	15.107	10.67	9.664	10.336	8.74	940	970	514	465	549	404	SLC47A1	solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031982//vesicle	GO:0005515//protein binding;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0022857//transmembrane transporter activity;GO:0042887//amide transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006812//cation transport;GO:0015695//organic cation transport;GO:0042886//amide transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:0097638//L-arginine import across plasma membrane;GO:0098655//cation transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1902600//proton transmembrane transport;GO:1903826//arginine transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000142507	49.981	56.638	59.635	59.794	52.425	60.471	855	973	753	757	757	752	PSMB6	proteasome 20S subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:9543]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02738;K02738;K02738;K02738;K02738;K02738;K02738;K02738	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0045296//cadherin binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000142511	0	0	0	0	0	0	0	0	0	0	0	0	GPR32	G protein-coupled receptor 32 [Source:HGNC Symbol;Acc:HGNC:4487]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004982//N-formyl peptide receptor activity	GO:0002430//complement receptor mediated signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration	--
ENSG00000142512	0	0	0	0	0.032	0	0	0	0	0	1	0	SIGLEC10	sialic acid binding Ig like lectin 10 [Source:HGNC Symbol;Acc:HGNC:15620]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0042169//SH2 domain binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0045087//innate immune response;GO:0106015//negative regulation of inflammatory response to wounding	--
ENSG00000142513	0	0	0	0	0	0	0	0	0	0	0	0	ACP4	acid phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:14376]	-	-	-	-	GO:0005764//lysosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane	GO:0003993//acid phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030971//receptor tyrosine kinase binding	GO:0007040//lysosome organization;GO:0010955//negative regulation of protein processing;GO:0010977//negative regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0042476//odontogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0120154//negative regulation of ERBB4 signaling pathway;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000142515	0	0	0	0	0	0	0	0	0	0	0	0	KLK3	kallikrein related peptidase 3 [Source:HGNC Symbol;Acc:HGNC:6364]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05215//Prostate cancer	K01351;K01351	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0030141//secretory granule;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	"GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"	GO:0002803//positive regulation of antibacterial peptide production;GO:0003073//regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0016525//negative regulation of angiogenesis;GO:0031638//zymogen activation;GO:0044267//cellular protein metabolic process	--
ENSG00000142528	6.509	5.9	6.144	5.205	5.127	4.204	550	531	404	340	354	271	ZNF473	zinc finger protein 473 [Source:HGNC Symbol;Acc:HGNC:23239]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015030//Cajal body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000142530	3.196	3.68	3.464	3.862	3.397	3.661	87.49	98.85	68.58	66.89	76.08	72.45	FAM71E1	family with sequence similarity 71 member E1 [Source:HGNC Symbol;Acc:HGNC:25107]	-	-	-	-	GO:0005794//Golgi apparatus	-	GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000142534	802.681	814.23	844.502	866.68	731.858	716.48	9540	9727	7413	7630	7349	6196	RPS11	ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:10384]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02949;K02949	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000142538	0	0	0	0	0	0	0	0	0	0	0	0	PTH2	parathyroid hormone 2 [Source:HGNC Symbol;Acc:HGNC:30828]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23143	GO:0005576//extracellular region	-	GO:0007218//neuropeptide signaling pathway	--
ENSG00000142539	0	0	0	0	0	0	0	0	0	0	0	0	SPIB	novel protein	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K02327;K02327;K02327;K02327;K02327	GO:0005634//nucleus	"GO:0000166//nucleotide binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0071897//DNA biosynthetic process"	ETS
ENSG00000142541	1154.272	1227.369	1151.347	1221.666	1129.001	1053.255	26989	28839	19878	21150	22297	17923	RPL13A	ribosomal protein L13a [Source:HGNC Symbol;Acc:HGNC:10304]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02872;K02872	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0097452//GAIT complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0071346//cellular response to interferon-gamma;GO:1901194//negative regulation of formation of translation preinitiation complex	--
ENSG00000142544	1.406	1.241	1.842	2.051	2.201	2.057	62	55	60	67	82	66	CTU1	cytosolic thiouridylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:29590]	Genetic Information Processing	"Folding, sorting and degradation"	ko04122//Sulfur relay system	K14168	GO:0002144//cytosolic tRNA wobble base thiouridylase complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0002098//tRNA wobble uridine modification;GO:0002143//tRNA wobble position uridine thiolation;GO:0008033//tRNA processing;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification	--
ENSG00000142546	19.899	20.587	18.486	23.406	21.508	24.725	464	508	308	414	422	413	NOSIP	nitric oxide synthase interacting protein [Source:HGNC Symbol;Acc:HGNC:17946]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043086//negative regulation of catalytic activity;GO:0051001//negative regulation of nitric-oxide synthase activity	--
ENSG00000142549	3.428	2.909	3.394	4.278	3.887	4.316	238	203	174	220	228	218	IGLON5	IgLON family member 5 [Source:HGNC Symbol;Acc:HGNC:34550]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000142552	7.68	7.394	6.221	4.981	5.267	4.059	234	223	140	109	132	82	RCN3	reticulocalbin 3 [Source:HGNC Symbol;Acc:HGNC:21145]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0009306//protein secretion;GO:0010952//positive regulation of peptidase activity;GO:0015031//protein transport;GO:0032964//collagen biosynthetic process;GO:0036503//ERAD pathway;GO:0043129//surfactant homeostasis;GO:0051896//regulation of protein kinase B signaling;GO:0055091//phospholipid homeostasis;GO:0060428//lung epithelium development	--
ENSG00000142556	3.291	2.613	2.226	2.25	2.778	2.192	301	211	134	154	198	139	ZNF614	zinc finger protein 614 [Source:HGNC Symbol;Acc:HGNC:24722]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000142583	1.739	1.294	1.304	1.833	1.149	1.826	63	42	34	34	32	58	SLC2A5	solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010]	Organismal Systems	Digestive system	ko04973//Carbohydrate digestion and absorption	K08143	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0035579//specific granule membrane;GO:0042383//sarcolemma;GO:0070062//extracellular exosome	GO:0005353//fructose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0070061//fructose binding	GO:0003044//regulation of systemic arterial blood pressure mediated by a chemical signal;GO:0005975//carbohydrate metabolic process;GO:0008643//carbohydrate transport;GO:0009750//response to fructose;GO:0015749//monosaccharide transmembrane transport;GO:0015755//fructose transmembrane transport;GO:0055085//transmembrane transport;GO:0071332//cellular response to fructose stimulus;GO:0106001//intestinal hexose absorption;GO:1904659//glucose transmembrane transport;GO:1990539//fructose import across plasma membrane	--
ENSG00000142599	23.348	21.527	17.688	16.488	19.666	19.498	2433	2758	1998	1814	2409	2131	RERE	arginine-glutamic acid dipeptide repeats [Source:HGNC Symbol;Acc:HGNC:9965]	Environmental Information Processing	Signal transduction	ko04391//Hippo signaling pathway - fly	K05628	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0043229//intracellular organelle	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0021549//cerebellum development;GO:0021691//cerebellar Purkinje cell layer maturation;GO:0021930//cerebellar granule cell precursor proliferation;GO:0021942//radial glia guided migration of Purkinje cell;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048755//branching morphogenesis of a nerve;GO:0048813//dendrite morphogenesis"	zf-GATA
ENSG00000142606	0.562	0.839	0.374	0.509	0.436	1.295	28.48	15.9	16.48	16.11	17	36.42	MMEL1	membrane metalloendopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:14668]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0016485//protein processing	--
ENSG00000142609	0.147	0.179	0.195	0.136	0.033	0.025	16	20	16	11	3	2	CFAP74	cilia and flagella associated protein 74 [Source:HGNC Symbol;Acc:HGNC:29368]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection	-	GO:0035082//axoneme assembly	--
ENSG00000142611	28.704	28.55	28.802	25.677	29.149	27.555	4291	4291	3254	2917	3734	2982	PRDM16	PR/SET domain 16 [Source:HGNC Symbol;Acc:HGNC:14000]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Amino acid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00310//Lysine degradation	K22410;K22410;K22410	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016235//aggresome;GO:0017053//transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0043457//regulation of cellular respiration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050873//brown fat cell differentiation;GO:0051567//histone H3-K9 methylation;GO:0070828//heterochromatin organization;GO:0120162//positive regulation of cold-induced thermogenesis"	zf-C2H2
ENSG00000142615	0	0	0	0	0	0	0	0	0	0	0	0	CELA2A	chymotrypsin like elastase 2A [Source:HGNC Symbol;Acc:HGNC:24609]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01346;K01346	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0036457//keratohyalin granule	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity	GO:0006508//proteolysis;GO:0032868//response to insulin;GO:0050796//regulation of insulin secretion;GO:0090330//regulation of platelet aggregation;GO:1901143//insulin catabolic process	--
ENSG00000142619	0.302	0.301	0.061	0.163	0.125	0.104	20	20	3	8	7	5	PADI3	peptidyl arginine deiminase 3 [Source:HGNC Symbol;Acc:HGNC:18337]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0018101//protein citrullination;GO:0036414//histone citrullination	--
ENSG00000142621	0.528	1.672	0.607	0.312	0.437	0.137	49	91	27	12	21	9	FHAD1	forkhead associated phosphopeptide binding domain 1 [Source:HGNC Symbol;Acc:HGNC:29408]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000142623	0.038	0.012	0	0	0	0	3	1	0	0	0	0	PADI1	peptidyl arginine deiminase 1 [Source:HGNC Symbol;Acc:HGNC:18367]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0018101//protein citrullination;GO:0036414//histone citrullination	--
ENSG00000142627	6.646	7.232	6.385	6.697	8.59	8.094	544	595	386	406	594	482	EPHA2	EPH receptor A2 [Source:HGNC Symbol;Acc:HGNC:3386]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance	K05103;K05103;K05103;K05103;K05103	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031256//leading edge membrane;GO:0031258//lamellipodium membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0070160//tight junction	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019838//growth factor binding;GO:0045296//cadherin binding	GO:0001501//skeletal system development;GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001649//osteoblast differentiation;GO:0001818//negative regulation of cytokine production;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007275//multicellular organism development;GO:0007411//axon guidance;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010591//regulation of lamellipodium assembly;GO:0014028//notochord formation;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0016525//negative regulation of angiogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021915//neural tube development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0030316//osteoclast differentiation;GO:0030335//positive regulation of cell migration;GO:0032682//negative regulation of chemokine production;GO:0033598//mammary gland epithelial cell proliferation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0033674//positive regulation of kinase activity;GO:0036342//post-anal tail morphogenesis;GO:0043491//protein kinase B signaling;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0046058//cAMP metabolic process;GO:0046718//viral entry into host cell;GO:0046849//bone remodeling;GO:0048013//ephrin receptor signaling pathway;GO:0048320//axial mesoderm formation;GO:0048514//blood vessel morphogenesis;GO:0048570//notochord morphogenesis;GO:0048870//cell motility;GO:0050830//defense response to Gram-positive bacterium;GO:0051898//negative regulation of protein kinase B signaling;GO:0060035//notochord cell development;GO:0060326//cell chemotaxis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0070309//lens fiber cell morphogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070848//response to growth factor;GO:0072659//protein localization to plasma membrane;GO:0090630//activation of GTPase activity;GO:1901491//negative regulation of lymphangiogenesis;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903348//positive regulation of bicellular tight junction assembly;GO:1904238//pericyte cell differentiation	--
ENSG00000142632	0.57	0.772	0.636	0.664	0.881	0.559	26	34	23	23	22	25	ARHGEF19	Rho guanine nucleotide exchange factor 19 [Source:HGNC Symbol;Acc:HGNC:26604]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0032956//regulation of actin cytoskeleton organization;GO:0042060//wound healing;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0090630//activation of GTPase activity"	--
ENSG00000142634	10.63	10.536	8.759	10.292	10.744	9.083	534	532	325	383	456	332	EFHD2	EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670]	-	-	-	-	GO:0016020//membrane;GO:0045121//membrane raft	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	-	--
ENSG00000142655	9.532	9.159	12.213	12.956	11.015	12.79	380	367	350	368	371	371	PEX14	peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13343	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:1990429//peroxisomal importomer complex	GO:0003714//transcription corepressor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0047485//protein N-terminus binding;GO:0048487//beta-tubulin binding	"GO:0007031//peroxisome organization;GO:0015031//protein transport;GO:0016558//protein import into peroxisome matrix;GO:0016560//protein import into peroxisome matrix, docking;GO:0016561//protein import into peroxisome matrix, translocation;GO:0032091//negative regulation of protein binding;GO:0034453//microtubule anchoring;GO:0036250//peroxisome transport along microtubule;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0044721//protein import into peroxisome matrix, substrate release;GO:0045892//negative regulation of transcription, DNA-templated;GO:0065003//protein-containing complex assembly"	--
ENSG00000142657	93.556	101.641	108.464	118.538	113.999	104.711	4326	4664	3627	3969	4448	3522	PGD	phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Metabolism of other amino acids;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00480//Glutathione metabolism;ko00030//Pentose phosphate pathway	K00033;K00033;K00033;K00033	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity;GO:0016491//oxidoreductase activity;GO:0050661//NADP binding	"GO:0006098//pentose-phosphate shunt;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0019322//pentose biosynthetic process;GO:0019521//D-gluconate metabolic process;GO:0046177//D-gluconate catabolic process"	--
ENSG00000142661	0.073	0.042	0.025	0.034	0.064	0.025	5	5	2	3	3	1	MYOM3	myomesin 3 [Source:HGNC Symbol;Acc:HGNC:26679]	-	-	-	-	GO:0005737//cytoplasm;GO:0031430//M band	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051015//actin filament binding	GO:0006936//muscle contraction	--
ENSG00000142669	123.153	129.612	108.169	108.982	104.756	83.055	1919	2030	1244.99	1258	1378.99	942	SH3BGRL3	SH3 domain binding glutamate rich protein like 3 [Source:HGNC Symbol;Acc:HGNC:15568]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000142675	0.296	0.333	0.182	0.089	0.091	0.159	9	16	7	3	4	6	CNKSR1	connector enhancer of kinase suppressor of Ras 1 [Source:HGNC Symbol;Acc:HGNC:19700]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0016020//membrane	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0030674//protein-macromolecule adaptor activity	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0016310//phosphorylation	--
ENSG00000142676	385.301	420.829	395.303	383.771	329.173	337.338	5811	6387	4398	4285	4205	3686	RPL11	ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:10301]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02868;K02868	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0032991//protein-containing complex;GO:0042788//polysomal ribosome;GO:0043232//intracellular non-membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008097//5S rRNA binding;GO:0019843//rRNA binding;GO:0031625//ubiquitin protein ligase binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0006605//protein targeting;GO:0010628//positive regulation of gene expression;GO:0032092//positive regulation of protein binding;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034504//protein localization to nucleus;GO:0042273//ribosomal large subunit biogenesis;GO:0050821//protein stabilization;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000435//negative regulation of protein neddylation	--
ENSG00000142677	0.017	0	0.023	0	0	0.024	1	0	1	0	0	1	IL22RA1	interleukin 22 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:13700]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05138;K05138;K05138	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004904//interferon receptor activity;GO:0005515//protein binding;GO:0042015//interleukin-20 binding	GO:0008150//biological_process;GO:0019221//cytokine-mediated signaling pathway;GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000142684	16.893	15.611	19.405	20.565	14.506	16.269	223.65	207.65	189.76	201.59	162.28	156.65	ZNF593	zinc finger protein 593 [Source:HGNC Symbol;Acc:HGNC:30943]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	--
ENSG00000142686	5.394	5.402	6.88	5.399	4.473	8.446	294	296	277	218	206	335	C1orf216	chromosome 1 open reading frame 216 [Source:HGNC Symbol;Acc:HGNC:26800]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000142687	36.843	37.781	40.536	39.639	41.036	41.74	2463	2665	2066	2030	2288	1992	KIAA0319L	KIAA0319 like [Source:HGNC Symbol;Acc:HGNC:30071]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	-	--
ENSG00000142694	11.491	10.835	11.306	10.213	10.123	12.015	233.58	221.38	169.74	153.78	173.85	177.71	EVA1B	eva-1 homolog B [Source:HGNC Symbol;Acc:HGNC:25558]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000142698	0	0	0	0	0	0	0	0	0	0	0	0	C1orf94	chromosome 1 open reading frame 94 [Source:HGNC Symbol;Acc:HGNC:28250]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000142700	0	0.017	0	0	0	0	0	1	0	0	0	0	DMRTA2	DMRT like family A2 [Source:HGNC Symbol;Acc:HGNC:13908]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007548//sex differentiation;GO:0021796//cerebral cortex regionalization;GO:0035914//skeletal muscle cell differentiation;GO:0048665//neuron fate specification;GO:0071542//dopaminergic neuron differentiation"	DM
ENSG00000142731	1.514	1.65	0.772	0.783	0.615	0.549	107	132	42	45	35	29	PLK4	polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397]	Environmental Information Processing	Signal transduction	ko04068//FoxO signaling pathway	K08863	GO:0000922//spindle pole;GO:0001741//XY body;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032154//cleavage furrow;GO:0098536//deuterosome;GO:0120098//procentriole;GO:0120099//procentriole replication complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007099//centriole replication;GO:0016310//phosphorylation;GO:0032465//regulation of cytokinesis;GO:0046601//positive regulation of centriole replication;GO:0060271//cilium assembly;GO:0060707//trophoblast giant cell differentiation;GO:0098535//de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	--
ENSG00000142733	5.305	3.441	3.621	4.013	3.069	3.115	357	314	243	240	235	205	MAP3K6	mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04425	-	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation	--
ENSG00000142748	0	0	0.063	0.063	0	0	0	0	1	1	0	0	FCN3	ficolin 3 [Source:HGNC Symbol;Acc:HGNC:3625]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0072562//blood microparticle;GO:1905370//serine-type endopeptidase complex	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0043654//recognition of apoptotic cell;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell;GO:0051607//defense response to virus;GO:1902679//negative regulation of RNA biosynthetic process;GO:1903028//positive regulation of opsonization"	--
ENSG00000142751	6.464	9.01	6.199	7.18	8.486	7.746	565	653	443	377	485	510	GPN2	GPN-loop GTPase 2 [Source:HGNC Symbol;Acc:HGNC:25513]	-	-	-	-	GO:0005575//cellular_component	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0008150//biological_process	--
ENSG00000142765	0.025	0	0	0.209	0.09	0.116	1	0	0	1	3	3	SYTL1	synaptotagmin like 1 [Source:HGNC Symbol;Acc:HGNC:15584]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0031528//microvillus membrane;GO:0042470//melanosome;GO:0070062//extracellular exosome;GO:0070382//exocytic vesicle	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042043//neurexin family protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis	--
ENSG00000142784	23.948	23.433	22.476	25.444	24.857	24.344	2073	1970	1434	1594	1766	1488	WDTC1	WD and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:29175]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006006//glucose metabolic process;GO:0008361//regulation of cell size;GO:0016567//protein ubiquitination;GO:0032869//cellular response to insulin stimulus;GO:0035264//multicellular organism growth;GO:0043086//negative regulation of catalytic activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0055082//cellular chemical homeostasis	--
ENSG00000142789	0	0	0	0	0	0	0	0	0	0	0	0	CELA3A	chymotrypsin like elastase 3A [Source:HGNC Symbol;Acc:HGNC:15944]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01345;K01345	GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000142794	3.135	3.39	3.029	2.928	3.046	3.091	206.04	277.1	164.13	167	203	161.03	NBPF3	NBPF member 3 [Source:HGNC Symbol;Acc:HGNC:25076]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000142798	25.763	32.737	24.854	26.832	33.19	24.626	6840	8246	5029	5113	7314.75	4910.16	HSPG2	heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273]	Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Signaling molecules and interaction	ko05205//Proteoglycans in cancer;ko05161//Hepatitis B;ko04512//ECM-receptor interaction	K06255;K06255;K06255	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0098797//plasma membrane protein complex	GO:0001540//amyloid-beta binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0046872//metal ion binding;GO:0050750//low-density lipoprotein particle receptor binding	GO:0001525//angiogenesis;GO:0006629//lipid metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006954//inflammatory response;GO:0007420//brain development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0072359//circulatory system development	--
ENSG00000142856	5.188	5.12	5.332	4.232	4.039	5.354	105	108	83	64	70	80	ITGB3BP	integrin subunit beta 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6157]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane"	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0034080//CENP-A containing nucleosome assembly;GO:0051301//cell division"	--
ENSG00000142864	112.231	104.381	99.73	96.872	94.695	89.441	7376	6907	4891	4595	5123	4335	SERBP1	SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0032183//SUMO binding;GO:0043022//ribosome binding;GO:0045296//cadherin binding	GO:0030578//PML body organization;GO:0043488//regulation of mRNA stability	--
ENSG00000142867	3.752	3.864	2.903	2.939	3.194	4.038	215	200	126	127	154	159	BCL10	BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Immune system;Immune system;Immune system	ko05131//Shigellosis;ko05152//Tuberculosis;ko04064//NF-kappa B signaling pathway;ko04662//B cell receptor signaling pathway;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway	K07368;K07368;K07368;K07368;K07368;K07368	GO:0001772//immunological synapse;GO:0002096//polkadots;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0032449//CBM complex;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm	GO:0002020//protease binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019209//kinase activator activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043422//protein kinase B binding;GO:0043621//protein self-association;GO:0044877//protein-containing complex binding;GO:0050700//CARD domain binding;GO:0051059//NF-kappaB binding;GO:0140296//general transcription initiation factor binding	"GO:0001783//B cell apoptotic process;GO:0001819//positive regulation of cytokine production;GO:0001843//neural tube closure;GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0006915//apoptotic process;GO:0006968//cellular defense response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008219//cell death;GO:0009620//response to fungus;GO:0016064//immunoglobulin mediated immune response;GO:0031398//positive regulation of protein ubiquitination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032094//response to food;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032761//positive regulation of lymphotoxin A production;GO:0032765//positive regulation of mast cell cytokine production;GO:0033674//positive regulation of kinase activity;GO:0042327//positive regulation of phosphorylation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050852//T cell receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization;GO:0061760//antifungal innate immune response;GO:0070231//T cell apoptotic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000142871	31.365	31.836	28.254	30.143	29.359	27.982	1482	1512	986	1055	1172	962	CCN1	cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0000166//nucleotide binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0019838//growth factor binding;GO:0050840//extracellular matrix binding	"GO:0001649//osteoblast differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0002041//intussusceptive angiogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0003281//ventricular septum development;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010518//positive regulation of phospholipase activity;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0030513//positive regulation of BMP signaling pathway;GO:0033690//positive regulation of osteoblast proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044319//wound healing, spreading of cells;GO:0045597//positive regulation of cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050793//regulation of developmental process;GO:0060413//atrial septum morphogenesis;GO:0060548//negative regulation of cell death;GO:0060591//chondroblast differentiation;GO:0060710//chorio-allantoic fusion;GO:0060716//labyrinthine layer blood vessel development;GO:0061036//positive regulation of cartilage development;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0072593//reactive oxygen species metabolic process;GO:0098609//cell-cell adhesion;GO:2000304//positive regulation of ceramide biosynthetic process"	--
ENSG00000142875	19.092	14.801	14.614	14.708	13.971	13.797	1626	1328	939	772	1059	931	PRKACB	protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]	Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Sensory system;Infectious disease: viral;Signal transduction;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Cancer: overview;Immune system;Substance dependence;Cellular community - eukaryotes;Infectious disease: parasitic;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Nervous system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Endocrine system;Nervous system;Nervous system;Nervous system;Endocrine system;Endocrine system;Endocrine system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Endocrine system;Substance dependence;Nervous system;Aging;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Excretory system;Infectious disease: bacterial;Substance dependence;Excretory system	"ko05200//Pathways in cancer;ko04740//Olfactory transduction;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04530//Tight junction;ko05146//Amoebiasis;ko04310//Wnt signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04340//Hedgehog signaling pathway;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0106310//protein serine kinase activity	GO:0001843//neural tube closure;GO:0003091//renal water homeostasis;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0010737//protein kinase A signaling;GO:0016310//phosphorylation;GO:0034380//high-density lipoprotein particle assembly;GO:0070613//regulation of protein processing;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	--
ENSG00000142892	41.167	37.397	34.302	28.07	28.767	32.169	2146	1918	1310	1179	1263	1273	PIGK	phosphatidylinositol glycan anchor biosynthesis class K [Source:HGNC Symbol;Acc:HGNC:8965]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05290;K05290	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042765//GPI-anchor transamidase complex;GO:0110165//cellular anatomical entity	GO:0003756//protein disulfide isomerase activity;GO:0003923//GPI-anchor transamidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0034235//GPI anchor binding	GO:0006506//GPI anchor biosynthetic process;GO:0006508//proteolysis;GO:0016255//attachment of GPI anchor to protein;GO:0034394//protein localization to cell surface	--
ENSG00000142910	9.333	10.432	4.88	5.22	8.145	7.356	427	480	165	177	315	245	TINAGL1	tubulointerstitial nephritis antigen like 1 [Source:HGNC Symbol;Acc:HGNC:19168]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity;GO:0043236//laminin binding	GO:0006508//proteolysis;GO:0016197//endosomal transport	--
ENSG00000142920	1.436	1.305	1.537	1.939	1.657	1.937	61	56	54	61	59	59	AZIN2	antizyme inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:29957]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K01583;K01583	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm;GO:1990005//granular vesicle	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008792//arginine decarboxylase activity;GO:0042978//ornithine decarboxylase activator activity	GO:0006591//ornithine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0007283//spermatogenesis;GO:0033387//putrescine biosynthetic process from ornithine;GO:0042177//negative regulation of protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0050790//regulation of catalytic activity;GO:0097055//agmatine biosynthetic process;GO:0098629//trans-Golgi network membrane organization;GO:1902269//positive regulation of polyamine transmembrane transport	--
ENSG00000142937	687.272	719.003	668.846	709.783	616.146	581.591	11078	11648	7964	8477	8388	6825	RPS8	ribosomal protein S8 [Source:HGNC Symbol;Acc:HGNC:10441]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02995;K02995	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006412//translation"	--
ENSG00000142945	0.955	1.44	0.876	1.183	0.658	1.281	51	58	34	52	33	37	KIF2C	kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K10393	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0035371//microtubule plus-end"	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity;GO:0019237//centromeric DNA binding;GO:0051010//microtubule plus-end binding	GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007080//mitotic metaphase plate congression;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051983//regulation of chromosome segregation	--
ENSG00000142949	39.168	37.666	37.368	32.751	36.754	36.648	5039	5056	3654	3237	4186	3493	PTPRF	protein tyrosine phosphatase receptor type F [Source:HGNC Symbol;Acc:HGNC:9670]	Environmental Information Processing;Organismal Systems;Human Diseases;Cellular Processes	Signaling molecules and interaction;Endocrine system;Endocrine and metabolic disease;Cellular community - eukaryotes	ko04514//Cell adhesion molecules;ko04910//Insulin signaling pathway;ko04931//Insulin resistance;ko04520//Adherens junction	K05695;K05695;K05695;K05695	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0035373//chondroitin sulfate proteoglycan binding;GO:0044877//protein-containing complex binding;GO:0050839//cell adhesion molecule binding	GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0010975//regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0016477//cell migration;GO:0031102//neuron projection regeneration;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0048679//regulation of axon regeneration;GO:0099560//synaptic membrane adhesion;GO:1900121//negative regulation of receptor binding	--
ENSG00000142959	0.134	0.172	0.052	0.052	0.091	0.132	7	9	2	2	4	5	BEST4	bestrophin 4 [Source:HGNC Symbol;Acc:HGNC:17106]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0003674//molecular_function;GO:0005254//chloride channel activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0008150//biological_process	--
ENSG00000142961	3.275	3.683	4.189	3.961	4.23	3.434	202	216	188	180	213	152	MOB3C	MOB kinase activator 3C [Source:HGNC Symbol;Acc:HGNC:29800]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity	--
ENSG00000142973	0	0	0	0	0	0	0	0	0	0	0	0	CYP4B1	cytochrome P450 family 4 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2644]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity;GO:1901363//heterocyclic compound binding"	GO:0006631//fatty acid metabolic process;GO:0018879//biphenyl metabolic process	--
ENSG00000143001	0	0	0.052	0	0	0	0	0	1	0	0	0	TMEM61	transmembrane protein 61 [Source:HGNC Symbol;Acc:HGNC:27296]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000143006	0	0	0	0	0	0	0	0	0	0	0	0	DMRTB1	DMRT like family B with proline rich C-terminal 1 [Source:HGNC Symbol;Acc:HGNC:13913]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007548//sex differentiation"	DM
ENSG00000143013	15.224	14.155	13.896	14.166	16.627	21.092	613	566	406	407	544	607	LMO4	LIM domain only 4 [Source:HGNC Symbol;Acc:HGNC:6644]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0031252//cell leading edge;GO:0090575//RNA polymerase II transcription regulator complex	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	GO:0001843//neural tube closure;GO:0003281//ventricular septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021514//ventral spinal cord interneuron differentiation;GO:0021522//spinal cord motor neuron differentiation;GO:0021527//spinal cord association neuron differentiation;GO:0030334//regulation of cell migration;GO:0031333//negative regulation of protein-containing complex assembly;GO:0033674//positive regulation of kinase activity;GO:0042659//regulation of cell fate specification;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048538//thymus development;GO:0050865//regulation of cell activation	--
ENSG00000143028	0.846	0.868	0.881	0.861	1.017	0.734	65	67	50	49	66	41	SYPL2	synaptophysin like 2 [Source:HGNC Symbol;Acc:HGNC:27638]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030672//synaptic vesicle membrane	-	GO:0006874//cellular calcium ion homeostasis;GO:0007507//heart development;GO:0021762//substantia nigra development;GO:0033292//T-tubule organization	--
ENSG00000143032	0	0	0	0	0	0	0	0	0	0	0	0	BARHL2	BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:954]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001709//cell fate determination;GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030182//neuron differentiation;GO:0030516//regulation of axon extension;GO:0045165//cell fate commitment;GO:0045727//positive regulation of translation;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000143033	5.382	5.138	5.201	3.803	4.311	4.706	454	436	317	223	297	281	MTF2	metal response element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:29535]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0035098//ESC/E(Z) complex	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007379//segment specification;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048863//stem cell differentiation;GO:0061086//negative regulation of histone H3-K27 methylation;GO:0061087//positive regulation of histone H3-K27 methylation;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000143036	20.995	19.354	18.745	18.805	19.447	20.061	902	878	623	571	672	599	SLC44A3	solute carrier family 44 member 3 [Source:HGNC Symbol;Acc:HGNC:28689]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K15282	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015220//choline transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0015871//choline transport;GO:0055085//transmembrane transport	--
ENSG00000143061	7.027	7.661	6.46	7.313	8.11	7.366	1058	1162	720	817	997	807	IGSF3	immunoglobulin superfamily member 3 [Source:HGNC Symbol;Acc:HGNC:5950]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0032808//lacrimal gland development	--
ENSG00000143067	2.558	2.364	2.96	2.578	2.353	2.779	296	275	253	221	230	234	ZNF697	zinc finger protein 697 [Source:HGNC Symbol;Acc:HGNC:32034]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000143079	7.88	6.952	6.278	5.069	5.641	5.767	817	723	461	365	429	422	CTTNBP2NL	CTTNBP2 N-terminal like [Source:HGNC Symbol;Acc:HGNC:25330]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding	GO:0006470//protein dephosphorylation;GO:0032410//negative regulation of transporter activity;GO:0034763//negative regulation of transmembrane transport	--
ENSG00000143093	11.383	11.222	13.428	12.67	11.476	11.897	769	762	670	634	655	584	STRIP1	striatin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:25916]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding	GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0030866//cortical actin cytoskeleton organization	--
ENSG00000143105	0	0	0	0	0	0	0	0	0	0	0	0	KCNA10	potassium voltage-gated channel subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:6219]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000143106	18.729	20.279	17.789	18.94	18.698	17.505	899	931	607	620	712	576	PSMA5	proteasome 20S subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:9534]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02729;K02729;K02729;K02729;K02729;K02729;K02729;K02729	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000143107	0	0	0	0	0	0	0	0	0	0	0	0	FNDC7	fibronectin type III domain containing 7 [Source:HGNC Symbol;Acc:HGNC:26668]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000143110	0.057	0.228	0	0	0	0	1	4	0	0	0	0	C1orf162	chromosome 1 open reading frame 162 [Source:HGNC Symbol;Acc:HGNC:28344]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000143119	0	0	0	0.043	0.265	0	0	0	0	1	7	0	CD53	CD53 molecule [Source:HGNC Symbol;Acc:HGNC:1686]	-	-	-	-	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:1901741//positive regulation of myoblast fusion	--
ENSG00000143125	0	0.069	0.047	0	0.041	0	0	2	1	0	1	0	PROK1	prokineticin 1 [Source:HGNC Symbol;Acc:HGNC:18454]	-	-	-	-	GO:0005576//extracellular region	GO:0008083//growth factor activity	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0045765//regulation of angiogenesis;GO:0051781//positive regulation of cell division	--
ENSG00000143126	14.549	15.511	16.7	15.871	17.894	17.541	3324	3562	2818	2686	3454	2916	CELSR2	cadherin EGF LAG seven-pass G-type receptor 2 [Source:HGNC Symbol;Acc:HGNC:3231]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding	"GO:0001764//neuron migration;GO:0003341//cilium movement;GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0021591//ventricular system development;GO:0021999//neural plate anterior/posterior regionalization;GO:0022407//regulation of cell-cell adhesion;GO:0032880//regulation of protein localization;GO:0033326//cerebrospinal fluid secretion;GO:0048813//dendrite morphogenesis;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060271//cilium assembly;GO:0098609//cell-cell adhesion"	--
ENSG00000143127	0.02	0.142	0.165	0.069	0.036	0.07	2	14	12	5	3	5	ITGA10	integrin subunit alpha 10 [Source:HGNC Symbol;Acc:HGNC:6135]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06586;K06586;K06586;K06586;K06586;K06586;K06586;K06586	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034680//integrin alpha10-beta1 complex	GO:0005178//integrin binding;GO:0005518//collagen binding;GO:0046872//metal ion binding;GO:0098639//collagen binding involved in cell-matrix adhesion	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0033627//cell adhesion mediated by integrin;GO:0098609//cell-cell adhesion	--
ENSG00000143147	2.462	2.624	2.309	2.707	2.24	2.374	372	399	248	261	281	266	GPR161	G protein-coupled receptor 161 [Source:HGNC Symbol;Acc:HGNC:23694]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K08439	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0042995//cell projection;GO:0055037//recycling endosome;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	--
ENSG00000143149	94.692	98.934	104.58	100.795	101.764	104.8	4704	4940	3837	3709	4271	3788	ALDH9A1	aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism"	K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149;K00149	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0033737//1-pyrroline dehydrogenase activity;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity;GO:0047105//4-trimethylammoniobutyraldehyde dehydrogenase activity"	GO:0006081//cellular aldehyde metabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0042445//hormone metabolic process;GO:0045329//carnitine biosynthetic process;GO:0051289//protein homotetramerization	--
ENSG00000143153	237.482	225.609	244.118	216.753	217.471	293.479	9077.45	8528.86	6727.74	6058.62	6785	7938.58	ATP1B1	ATPase Na+/K+ transporting subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:804]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540;K01540	GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005901//caveola;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030315//T-tubule;GO:0031090//organelle membrane;GO:0036126//sperm flagellum;GO:0042383//sarcolemma;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0001671//ATPase activator activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019901//protein kinase binding;GO:0023026//MHC class II protein complex binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046982//protein heterodimerization activity;GO:0051117//ATPase binding	GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006883//cellular sodium ion homeostasis;GO:0007155//cell adhesion;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0010468//regulation of gene expression;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0030001//metal ion transport;GO:0030007//cellular potassium ion homeostasis;GO:0032781//positive regulation of ATPase activity;GO:0035725//sodium ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0044861//protein transport into plasma membrane raft;GO:0046034//ATP metabolic process;GO:0050821//protein stabilization;GO:0055119//relaxation of cardiac muscle;GO:0060048//cardiac muscle contraction;GO:0072659//protein localization to plasma membrane;GO:0086009//membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0098655//cation transmembrane transport;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1902600//proton transmembrane transport;GO:1903169//regulation of calcium ion transmembrane transport;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:1903281//positive regulation of calcium:sodium antiporter activity;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:1903408//positive regulation of P-type sodium:potassium-exchanging transporter activity;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000143155	13.991	11.823	11.148	10.442	11.763	10.962	870	739	512	481	618	496	TIPRL	TOR signaling pathway regulator [Source:HGNC Symbol;Acc:HGNC:30231]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0031929//TOR signaling;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000143156	11.545	10.316	10.176	8.917	9.675	11.029	357.55	326.14	232.26	204.38	252	246.42	NME7	NME/NM23 family member 7 [Source:HGNC Symbol;Acc:HGNC:20461]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005813//centrosome;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation	--
ENSG00000143157	19.207	15.599	18.883	16.456	17.491	19.683	2012	1825	1518	1390	1574	1569	POGK	pogo transposable element derived with KRAB domain [Source:HGNC Symbol;Acc:HGNC:18800]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000143158	13.93	12.316	15.731	14.738	13.682	14.427	629	559	508	493	522	474	MPC2	mitochondrial pyruvate carrier 2 [Source:HGNC Symbol;Acc:HGNC:24515]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K22139	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0098800//inner mitochondrial membrane protein complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0050833//pyruvate transmembrane transporter activity	GO:0006850//mitochondrial pyruvate transmembrane transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate	--
ENSG00000143162	52.189	47.585	40.835	45.7	44.096	42.965	2132	1954	1232	1383	1522	1277	CREG1	cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005667//transcription regulator complex;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003714//transcription corepressor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0040008//regulation of growth;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000143164	21.824	18.861	18.395	14.803	15.611	17.298	1466	1273	912	736	887	843	DCAF6	DDB1 and CUL4 associated factor 6 [Source:HGNC Symbol;Acc:HGNC:30002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	GO:0016567//protein ubiquitination;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000143167	0.057	0.056	0.205	0.417	0.134	0.326	3	3	8	12	6	6	GPA33	glycoprotein A33 [Source:HGNC Symbol;Acc:HGNC:4445]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0038023//signaling receptor activity	-	--
ENSG00000143171	0.606	0.227	0.552	0.45	0.352	0.689	25	10	17	14	13	21	RXRG	retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Cardiovascular disease;Cancer: overview;Cancer: specific types;Endocrine system;Immune system;Endocrine system;Cancer: specific types;Endocrine system;Cancer: specific types;Endocrine system;Cancer: specific types	"ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko05226//Gastric cancer;ko04919//Thyroid hormone signaling pathway;ko04659//Th17 cell differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko05222//Small cell lung cancer;ko03320//PPAR signaling pathway;ko05223//Non-small cell lung cancer;ko04920//Adipocytokine signaling pathway;ko05216//Thyroid cancer"	K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526;K08526	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007422//peripheral nervous system development;GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0031641//regulation of myelination;GO:0032526//response to retinoic acid;GO:0032870//cellular response to hormone stimulus;GO:0043401//steroid hormone mediated signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048856//anatomical structure development"	RXR-like
ENSG00000143178	0.165	0.315	0.235	0.037	0.13	0.133	9	14	8	1	4	6	TBX19	T-box transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11596]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001707//mesoderm formation;GO:0001708//cell fate specification;GO:0003007//heart morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0021983//pituitary gland development;GO:0042127//regulation of cell population proliferation;GO:0045165//cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	T-box
ENSG00000143179	7.856	6.994	6.678	6.667	5.206	6.202	362	387	269	272	293	278	UCK2	uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00876;K00876;K00876	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004849//uridine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019206//nucleoside kinase activity;GO:0042802//identical protein binding	GO:0016310//phosphorylation;GO:0044206//UMP salvage;GO:0044211//CTP salvage;GO:0071704//organic substance metabolic process	--
ENSG00000143183	91.481	86.653	90.514	93.311	84.45	95.875	2537	2372	1722	1740	1925	1772	TMCO1	transmembrane and coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:18188]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006983//ER overload response;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport	--
ENSG00000143184	0	0.039	0	0	0.093	0	0	1	0	0	2	0	XCL1	X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05507;K05507;K05507	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0042379//chemokine receptor binding;GO:0042803//protein homodimerization activity;GO:0048020//CCR chemokine receptor binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002548//monocyte chemotaxis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002725//negative regulation of T cell cytokine production;GO:0002726//positive regulation of T cell cytokine production;GO:0002826//negative regulation of T-helper 1 type immune response;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0010820//positive regulation of T cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0032733//positive regulation of interleukin-10 production;GO:0035782//mature natural killer cell chemotaxis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043547//positive regulation of GTPase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048247//lymphocyte chemotaxis;GO:0050727//regulation of inflammatory response;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071353//cellular response to interleukin-4;GO:0071356//cellular response to tumor necrosis factor;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071636//positive regulation of transforming growth factor beta production;GO:0071663//positive regulation of granzyme B production;GO:0090023//positive regulation of neutrophil chemotaxis;GO:2000412//positive regulation of thymocyte migration;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:2000513//positive regulation of granzyme A production;GO:2000518//negative regulation of T-helper 1 cell activation;GO:2000538//positive regulation of B cell chemotaxis;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2000556//positive regulation of T-helper 1 cell cytokine production;GO:2000558//positive regulation of immunoglobulin production in mucosal tissue;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000566//positive regulation of CD8-positive, alpha-beta T cell proliferation"	--
ENSG00000143185	0	0	0	0	0	0	0	0	0	0	0	0	XCL2	X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22675;K22675;K22675	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008015//blood circulation;GO:0010820//positive regulation of T cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000143190	1.923	1.581	1.757	1.289	1.576	1.149	542	442	362	238	369	240	POU2F1	POU class 2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9212]	Human Diseases;Human Diseases	Infectious disease: viral;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko05417//Lipid and atherosclerosis	K09364;K09364	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Pou
ENSG00000143194	1.446	1.69	1.613	1.696	0.705	1.312	51	51	42	40	21	32	MAEL	maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929]	-	-	-	-	GO:0000785//chromatin;GO:0001741//XY body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030849//autosome;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0048471//perinuclear region of cytoplasm;GO:0071547//piP-body	GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0006974//cellular response to DNA damage stimulus;GO:0007129//homologous chromosome pairing at meiosis;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009566//fertilization;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046620//regulation of organ growth;GO:0051321//meiotic cell cycle;GO:0060964//regulation of gene silencing by miRNA"	HMG
ENSG00000143195	4.733	3.681	5.927	2.883	3.634	4.313	956	827	844	464	614	599	ILDR2	immunoglobulin like domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:18131]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070160//tight junction	-	GO:0009749//response to glucose;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0031016//pancreas development;GO:0043484//regulation of RNA splicing;GO:0048873//homeostasis of number of cells within a tissue;GO:0050868//negative regulation of T cell activation	--
ENSG00000143196	0	0	0	0	0.332	0	0	0	0	0	10	0	DPT	dermatopontin [Source:HGNC Symbol;Acc:HGNC:3011]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0030199//collagen fibril organization	--
ENSG00000143198	39.086	41.814	40.72	44.522	34.18	34.65	702	700	526	568	502	448	MGST3	microsomal glutathione S-transferase 3 [Source:HGNC Symbol;Acc:HGNC:7064]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004464//leukotriene-C4 synthase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000143199	0	0	0.093	0	0	0	0	0	1	0	0	0	ADCY10	adenylate cyclase 10 [Source:HGNC Symbol;Acc:HGNC:21285]	Metabolism;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Metabolism;Organismal Systems;Organismal Systems	Global and overview maps;Environmental adaptation;Signal transduction;Signal transduction;Nucleotide metabolism;Endocrine system;Environmental adaptation	"ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04024//cAMP signaling pathway;ko04371//Apelin signaling pathway;ko00230//Purine metabolism;ko04935//Growth hormone synthesis, secretion and action;ko04713//Circadian entrainment"	K11265;K11265;K11265;K11265;K11265;K11265;K11265	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045177//apical part of cell;GO:0045178//basal part of cell;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding;GO:0071890//bicarbonate binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0006171//cAMP biosynthetic process;GO:0007283//spermatogenesis;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0071241//cellular response to inorganic substance	--
ENSG00000143207	12.679	10.924	11.274	9.467	10.029	14.038	588	556	400	363	425	460	COP1	COP1 E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:17440]	Genetic Information Processing;Cellular Processes	"Folding, sorting and degradation;Cell growth and death"	ko04120//Ubiquitin mediated proteolysis;ko04115//p53 signaling pathway	K10143;K10143	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010212//response to ionizing radiation;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000143217	0	0	0	0	0.033	0	0	0	0	0	2	0	NECTIN4	nectin cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:19688]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K06593	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0046718//viral entry into host cell	--
ENSG00000143222	59.07	64.223	61.675	58.783	59.828	55.142	1088	1189	839	802	931	739	UFC1	ubiquitin-fold modifier conjugating enzyme 1 [Source:HGNC Symbol;Acc:HGNC:26941]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0061657//UFM1 conjugating enzyme activity;GO:0071568//UFM1 transferase activity	GO:0007420//brain development;GO:0034976//response to endoplasmic reticulum stress;GO:0061709//reticulophagy;GO:0071569//protein ufmylation;GO:1990592//protein K69-linked ufmylation	--
ENSG00000143224	4.823	6.512	6.999	5.35	6.382	7.697	145.02	215.03	177	139	182.16	185	PPOX	protoporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:9280]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K00231;K00231	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0004729//oxygen-dependent protoporphyrinogen oxidase activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process	--
ENSG00000143226	0.407	0.258	0.491	0.123	0.295	0.414	17	10	13	5	10	13	FCGR2A	Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: parasitic;Development and regeneration;Immune system	ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko04611//Platelet activation	K06472;K06472;K06472;K06472;K06472;K06472;K06472;K06472;K06472;K06472;K06472;K06472	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019864//IgG binding	GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response	--
ENSG00000143228	0.288	0.44	0.496	0.035	0.159	0.468	11	18	14	1	4	13	NUF2	NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031262//Ndc80 complex;GO:0031617//NMS complex"	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0045132//meiotic chromosome segregation;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051383//kinetochore organization	--
ENSG00000143248	23.132	22.646	15.232	19.571	16.489	16.71	1336	1188	615	696	725	628	RGS5	regulator of G protein signaling 5 [Source:HGNC Symbol;Acc:HGNC:10001]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000143252	60.074	54.483	60.489	70.282	62.7	67.119	1406	1350	1095	1238	1209	1177	SDHC	succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236;K00236	"GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045281//succinate dehydrogenase complex"	"GO:0000104//succinate dehydrogenase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0020037//heme binding;GO:0046872//metal ion binding"	"GO:0006099//tricarboxylic acid cycle;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000143256	12.577	10.588	12.335	11.428	10.306	15.402	156	132	113	105	108	139	PFDN2	prefoldin subunit 2 [Source:HGNC Symbol;Acc:HGNC:8867]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016272//prefoldin complex;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0050821//protein stabilization;GO:0051495//positive regulation of cytoskeleton organization;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000143257	0.15	0.033	0.106	0.09	0.139	0.388	4.02	1	2.33	2	3	5	NR1I3	nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969]	Human Diseases	Cancer: overview	ko05207//Chemical carcinogenesis - receptor activation	K08541	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	THR-like
ENSG00000143258	10.555	11.123	12.89	12.04	13.217	14.677	477	511	411	418	490	457	USP21	ubiquitin specific peptidase 21 [Source:HGNC Symbol;Acc:HGNC:12620]	Cellular Processes	Cell growth and death	ko04217//Necroptosis	K21634	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003713//transcription coactivator activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019784//NEDD8-specific protease activity;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000143278	0	0	0	0	0	0	0	0	0	0	0	0	F13B	coagulation factor XIII B chain [Source:HGNC Symbol;Acc:HGNC:3534]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05171//Coronavirus disease - COVID-19;ko04610//Complement and coagulation cascades	K03906;K03906	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:1990234//transferase complex	-	"GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0018149//peptide cross-linking;GO:0072378//blood coagulation, fibrin clot formation"	--
ENSG00000143294	32.447	31.614	34.204	32.631	33.962	35.202	1366	1342	1007	1016	1196	1091	PRCC	proline rich mitotic checkpoint control factor [Source:HGNC Symbol;Acc:HGNC:9343]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05211//Renal cell carcinoma	K13105;K13105	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051726//regulation of cell cycle	--
ENSG00000143297	0	0	0	0	0	0	0	0	0	0	0	0	FCRL5	Fc receptor like 5 [Source:HGNC Symbol;Acc:HGNC:18508]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000143303	5.33	6.164	7.666	9.366	8.197	7.858	215	246	221	260	274	213	METTL25B	methyltransferase like 25B [Source:HGNC Symbol;Acc:HGNC:24273]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0008649//rRNA methyltransferase activity"	GO:0000154//rRNA modification;GO:0031167//rRNA methylation	--
ENSG00000143314	20.739	21.594	19.949	24.914	22.089	19.562	380	386	270	338	337	257	MRPL24	mitochondrial ribosomal protein L24 [Source:HGNC Symbol;Acc:HGNC:14037]	Genetic Information Processing	Translation	ko03010//Ribosome	K02895	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0010467//gene expression;GO:0032543//mitochondrial translation	--
ENSG00000143315	4.617	4.648	4.554	4.383	4.468	4.792	674	682	491	474	551	509	PIGM	phosphatidylinositol glycan anchor biosynthesis class M [Source:HGNC Symbol;Acc:HGNC:18858]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05284;K05284	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990529//glycosylphosphatidylinositol-mannosyltransferase I complex	"GO:0000030//mannosyltransferase activity;GO:0004376//glycolipid mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0051751//alpha-1,4-mannosyltransferase activity"	GO:0006506//GPI anchor biosynthetic process;GO:0097502//mannosylation	--
ENSG00000143318	0.026	0	0.219	0.069	0	0.378	1	0	2	2	0	4	CASQ1	calsequestrin 1 [Source:HGNC Symbol;Acc:HGNC:1512]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K23468	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005790//smooth endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0014802//terminal cisterna;GO:0014804//terminal cisterna lumen;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030016//myofibril;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0042383//sarcolemma;GO:0043231//intracellular membrane-bounded organelle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007029//endoplasmic reticulum organization;GO:0007519//skeletal muscle tissue development;GO:0009408//response to heat;GO:0010033//response to organic substance;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0014870//response to muscle inactivity;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0045214//sarcomere organization;GO:0051258//protein polymerization;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051282//regulation of sequestering of calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000143319	10.509	9.802	9.823	10.919	12.476	10.237	704	660.7	481.98	544	705	500	ISG20L2	interferon stimulated exonuclease gene 20 like 2 [Source:HGNC Symbol;Acc:HGNC:25745]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0042254//ribosome biogenesis;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000143320	24.557	21.816	12.667	12.696	14.471	10.528	496	443	189	190	247	149	CRABP2	cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0001972//retinoic acid binding;GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0030332//cyclin binding	"GO:0002138//retinoic acid biosynthetic process;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0008544//epidermis development;GO:0015908//fatty acid transport;GO:0035115//embryonic forelimb morphogenesis;GO:0042573//retinoic acid metabolic process;GO:0048672//positive regulation of collateral sprouting"	--
ENSG00000143321	105.068	104.15	116.637	114.029	110.686	124.767	4801	4745	3846	3978	4366	4277	HDGF	heparin binding growth factor [Source:HGNC Symbol;Acc:HGNC:4856]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex;GO:0062023//collagen-containing extracellular matrix	"GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0015631//tubulin binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0034504//protein localization to nucleus;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051781//positive regulation of cell division;GO:0098761//cellular response to interleukin-7	--
ENSG00000143322	31.678	29.384	35.901	36.642	34.646	42.094	6388	6177	5719	5610	6254	6441	ABL2	"ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]"	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing	Signal transduction;Cancer: overview;Cardiovascular disease;Signal transduction	ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05416//Viral myocarditis;ko04012//ErbB signaling pathway	K08887;K08887;K08887;K08887	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001784//phosphotyrosine residue binding;GO:0003785//actin monomer binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010506//regulation of autophagy;GO:0010863//positive regulation of phospholipase C activity;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030100//regulation of endocytosis;GO:0030155//regulation of cell adhesion;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035640//exploration behavior;GO:0051353//positive regulation of oxidoreductase activity;GO:0071300//cellular response to retinoic acid;GO:2000145//regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000143324	20.568	19.268	20.967	20.698	20.349	23.069	2340	2112	1728	1613	1877	1821	XPR1	xenotropic and polytropic retrovirus receptor 1 [Source:HGNC Symbol;Acc:HGNC:12827]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0000822//inositol hexakisphosphate binding;GO:0001618//virus receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0015114//phosphate ion transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0038023//signaling receptor activity	GO:0006817//phosphate ion transport;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009615//response to virus;GO:0016036//cellular response to phosphate starvation;GO:0030643//cellular phosphate ion homeostasis;GO:0035435//phosphate ion transmembrane transport;GO:0046718//viral entry into host cell	--
ENSG00000143333	0.581	0.578	0.352	0.676	0.664	0.413	29	29	13	25	28	15	RGS16	regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031224//intrinsic component of membrane	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0043547//positive regulation of GTPase activity	--
ENSG00000143337	29.955	29.069	28.052	24.586	28.452	26.083	2293	2209.03	1570	1374	1648	1462	TOR1AIP1	torsin 1A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29456]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0008092//cytoskeletal protein binding;GO:0051117//ATPase binding	GO:0032781//positive regulation of ATPase activity;GO:0034504//protein localization to nucleus;GO:0061024//membrane organization;GO:0071763//nuclear membrane organization;GO:0090435//protein localization to nuclear envelope	--
ENSG00000143340	0.347	0.19	0.352	1.147	0.698	1.62	20	11	15	49	34	68	FAM163A	family with sequence similarity 163 member A [Source:HGNC Symbol;Acc:HGNC:28274]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000143341	3.333	2.053	2.026	0.624	0.963	1.304	739	632	291	176	310	215	HMCN1	hemicentin 1 [Source:HGNC Symbol;Acc:HGNC:19194]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005927//muscle tendon junction;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0032154//cleavage furrow;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007601//visual perception;GO:0009617//response to bacterium;GO:0050896//response to stimulus;GO:0051301//cell division;GO:0071711//basement membrane organization;GO:0090527//actin filament reorganization	--
ENSG00000143344	35.813	36.585	38.904	27.923	28.464	33.303	3513	3615	2821	2035	2361	2379	RGL1	ral guanine nucleotide dissociation stimulator like 1 [Source:HGNC Symbol;Acc:HGNC:30281]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17635	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity	--
ENSG00000143353	9.359	8.237	7.674	10.49	8.937	9.773	358	317	217	299	289	273	LYPLAL1	lysophospholipase like 1 [Source:HGNC Symbol;Acc:HGNC:20440]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004622//lysophospholipase activity;GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0002084//protein depalmitoylation;GO:0008150//biological_process	--
ENSG00000143355	0.043	0.013	0.133	0.035	0.039	0.009	7	2	6	4	3	1	LHX9	LIM homeobox 9 [Source:HGNC Symbol;Acc:HGNC:14222]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0030182//neuron differentiation;GO:0035262//gonad morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0097380//dorsal spinal cord interneuron anterior axon guidance"	Homeobox
ENSG00000143363	13.685	13.576	14.023	15.532	16.363	17.599	776	785	623	670	784	722	PRUNE1	prune exopolyphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:13420]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01514;K01514	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0004309//exopolyphosphatase activity;GO:0004427//inorganic diphosphatase activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation;GO:0031113//regulation of microtubule polymerization;GO:0050767//regulation of neurogenesis	--
ENSG00000143365	5.979	7.266	6.097	5.977	6.406	5.437	340	454	278	253	293	228	RORC	RAR related orphan receptor C [Source:HGNC Symbol;Acc:HGNC:10260]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Immune disease;Environmental adaptation	ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease;ko04710//Circadian rhythm	K08534;K08534;K08534	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008142//oxysterol binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0098531//ligand-activated transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006805//xenobiotic metabolic process;GO:0010468//regulation of gene expression;GO:0010906//regulation of glucose metabolic process;GO:0019218//regulation of steroid metabolic process;GO:0030522//intracellular receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0036315//cellular response to sterol;GO:0042093//T-helper cell differentiation;GO:0042753//positive regulation of circadian rhythm;GO:0045598//regulation of fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0048535//lymph node development;GO:0048541//Peyer's patch development;GO:0060612//adipose tissue development;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0072539//T-helper 17 cell differentiation"	THR-like
ENSG00000143367	4.069	4.088	3.841	3.283	4.095	3.452	258	259	179	153	218	158	TUFT1	tuftelin 1 [Source:HGNC Symbol;Acc:HGNC:12422]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030345//structural constituent of tooth enamel	GO:0030282//bone mineralization;GO:0031214//biomineral tissue development;GO:0035556//intracellular signal transduction;GO:0042476//odontogenesis	--
ENSG00000143368	30.569	28.984	30.694	34.566	32.644	35.276	979	933	726	820	880	822	SF3B4	splicing factor 3b subunit 4 [Source:HGNC Symbol;Acc:HGNC:10771]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12831	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0071005//U2-type precatalytic spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:1990935//splicing factor binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000143369	0.388	0.349	0.17	0.372	0.614	0.192	15	14	5	11	22	5	ECM1	extracellular matrix protein 1 [Source:HGNC Symbol;Acc:HGNC:3153]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005134//interleukin-2 receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0043236//laminin binding	GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002063//chondrocyte development;GO:0002828//regulation of type 2 immune response;GO:0003416//endochondral bone growth;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0010466//negative regulation of peptidase activity;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045766//positive regulation of angiogenesis;GO:2000404//regulation of T cell migration	--
ENSG00000143373	9.368	9.803	10.819	9.751	11.089	9.974	911.92	965.97	752	708.35	887.07	713.33	ZNF687	zinc finger protein 687 [Source:HGNC Symbol;Acc:HGNC:29277]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000143374	11.252	11.785	11.41	13.584	11.968	13.38	577	633	448	531	523	501	TARS2	"threonyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30740]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01868	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004829//threonine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042803//protein homodimerization activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006435//threonyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0070159//mitochondrial threonyl-tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000143375	0.586	0.809	0.87	3.225	1.063	1.078	62	86	68	93	95	83	CGN	cingulin [Source:HGNC Symbol;Acc:HGNC:17429]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06102	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016459//myosin complex;GO:0030054//cell junction	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0008150//biological_process	--
ENSG00000143376	6.57	6.053	8.222	4.745	5.719	8.294	871	845	757	465	589	745	SNX27	sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073]	-	-	-	-	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030904//retromer complex;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071203//WASH complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding	GO:0001770//establishment of natural killer cell polarity;GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0032456//endocytic recycling	--
ENSG00000143379	13.57	14.831	13.929	11.559	13.4	15.733	1017.96	1046.91	805.95	731	876.97	773	SETDB1	SET domain bifurcated histone lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10761]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Cellular community - eukaryotes;Amino acid metabolism	ko01100//Metabolic pathways;ko04550//Signaling pathways regulating pluripotency of stem cells;ko00310//Lysine degradation	K11421;K11421;K11421	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:1990841//promoter-specific chromatin binding	GO:0006325//chromatin organization;GO:0007265//Ras protein signal transduction;GO:0010629//negative regulation of gene expression;GO:0032259//methylation;GO:0033273//response to vitamin;GO:0034968//histone lysine methylation;GO:0045471//response to ethanol;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051567//histone H3-K9 methylation;GO:0070828//heterochromatin organization;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly	MBD
ENSG00000143382	9.839	10.898	13.46	12.903	13.478	11.06	832	947	864	813	980	683	ADAMTSL4	ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706]	-	-	-	-	GO:0005576//extracellular region;GO:0005614//interstitial matrix;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0002020//protease binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002064//epithelial cell development;GO:0006915//apoptotic process;GO:0030198//extracellular matrix organization;GO:0043065//positive regulation of apoptotic process	--
ENSG00000143384	55.387	53.908	60.788	55.331	52.608	58.512	4524	4421	3617	3358	3636	3474	MCL1	"MCL1 apoptosis regulator, BCL2 family member [Source:HGNC Symbol;Acc:HGNC:6943]"	Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes	Signal transduction;Cancer: overview;Signal transduction;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko04210//Apoptosis	K02539;K02539;K02539;K02539	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097136//Bcl-2 family protein complex	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051434//BH3 domain binding	GO:0001709//cell fate determination;GO:0006915//apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010507//negative regulation of autophagy;GO:0012501//programmed cell death;GO:0019725//cellular homeostasis;GO:0030154//cell differentiation;GO:0034097//response to cytokine;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0071806//protein transmembrane transport;GO:0080135//regulation of cellular response to stress;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1903378//positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:2000811//negative regulation of anoikis;GO:2001020//regulation of response to DNA damage stimulus;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000143387	19.787	24.271	18.668	14.205	15.993	11.574	748	900	524	390	510	331	CTSK	cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems	Immune disease;Cell growth and death;Transport and catabolism;Development and regeneration;Immune system	ko05323//Rheumatoid arthritis;ko04210//Apoptosis;ko04142//Lysosome;ko04380//Osteoclast differentiation;ko04620//Toll-like receptor signaling pathway	K01371;K01371;K01371;K01371;K01371	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0036021//endolysosome lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0001968//fibronectin binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043394//proteoglycan binding	GO:0000422//autophagy of mitochondrion;GO:0001957//intramembranous ossification;GO:0006508//proteolysis;GO:0006590//thyroid hormone generation;GO:0006955//immune response;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0045453//bone resorption;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0061037//negative regulation of cartilage development	--
ENSG00000143390	18.634	20.355	17.95	20.599	20.975	19.244	955	948	694	720	769	726	RFX5	regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune disease;Immune system	ko05152//Tuberculosis;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation	K08061;K08061;K08061	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	RFX
ENSG00000143393	24.608	25.375	27.966	24.182	24.728	28.093	1865.08	1776.03	1507	1342.65	1529.93	1459.67	PI4KB	phosphatidylinositol 4-kinase beta [Source:HGNC Symbol;Acc:HGNC:8984]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K19801;K19801;K19801	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0071889//14-3-3 protein binding	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006898//receptor-mediated endocytosis;GO:0007040//lysosome organization;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0044238//primary metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000143398	15.992	15.658	17.209	16.54	18.039	18.727	1246	1226	977	954	1172	997	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]	Metabolism;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Cell motility;Signal transduction;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cancer: overview;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0032587//ruffle membrane;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0000285//1-phosphatidylinositol-3-phosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0052810//1-phosphatidylinositol-5-kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0006629//lipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0008654//phospholipid biosynthetic process;GO:0010761//fibroblast migration;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030216//keratinocyte differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048041//focal adhesion assembly;GO:0060326//cell chemotaxis;GO:0072659//protein localization to plasma membrane;GO:0090630//activation of GTPase activity;GO:0097178//ruffle assembly	--
ENSG00000143401	14.617	12.004	13.783	10.552	10.742	10.933	936	774	658	527	606	527	ANP32E	acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673]	-	-	-	-	GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0019212//phosphatase inhibitor activity;GO:0042393//histone binding	GO:0006325//chromatin organization;GO:0042981//regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043486//histone exchange	--
ENSG00000143409	19.28	20.314	22.821	22.044	21.11	25.845	971	1109	882	904	986	1006	MINDY1	MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016807//cysteine-type carboxypeptidase activity;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0008150//biological_process;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000143412	1.43	1.051	1.473	0.839	0.625	0.726	46	34	35	20	17	17	ANXA9	annexin A9 [Source:HGNC Symbol;Acc:HGNC:547]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0031982//vesicle;GO:0045202//synapse	"GO:0001786//phosphatidylserine binding;GO:0002020//protease binding;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0015464//acetylcholine receptor activity;GO:0019834//phospholipase A2 inhibitor activity;GO:0046790//virion binding"	"GO:0007271//synaptic transmission, cholinergic;GO:0043086//negative regulation of catalytic activity;GO:0070588//calcium ion transmembrane transport;GO:0098609//cell-cell adhesion"	--
ENSG00000143416	38.585	40.179	47.946	46.124	45.792	56.335	1384	1439	1245	1223	1374	1469	SELENBP1	selenium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10719]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K17285;K17285	GO:0001650//fibrillar center;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity;GO:0018549//methanethiol oxidase activity	GO:0015031//protein transport	--
ENSG00000143418	137.214	127.103	141.432	154.842	135.013	147.69	6011.04	5755.09	4654.05	4795	5129.03	4757	CERS2	ceramide synthase 2 [Source:HGNC Symbol;Acc:HGNC:14076]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K24621;K24621;K24621	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0048681//negative regulation of axon regeneration;GO:1900148//negative regulation of Schwann cell migration;GO:1905045//negative regulation of Schwann cell proliferation involved in axon regeneration	--
ENSG00000143420	53.449	53.446	59.717	56.886	46.18	46.11	1714	1725	1390	1354	1299	1109	ENSA	endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008200//ion channel inhibitor activity;GO:0019212//phosphatase inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007584//response to nutrient;GO:0035308//negative regulation of protein dephosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity;GO:0050796//regulation of insulin secretion;GO:0051301//cell division	--
ENSG00000143434	0.959	1.263	0.893	0.655	0.427	0.603	77	102	56	39	29	36	SEMA6C	semaphorin 6C [Source:HGNC Symbol;Acc:HGNC:10740]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06842	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000143436	16.181	16.958	18.659	18.329	17.562	16.134	401.99	410	338	331	360	289	MRPL9	mitochondrial ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:14277]	Genetic Information Processing	Translation	ko03010//Ribosome	K02939	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000143437	16.647	14.904	15.097	13.249	14.675	13.457	1312	1234	911	775	988	800	ARNT	aryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Acc:HGNC:700]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Cancer: overview;Cancer: overview;Endocrine and metabolic disease;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko04934//Cushing syndrome;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09097;K09097;K09097;K09097;K09097;K09097	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0034751//aryl hydrocarbon receptor complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001666//response to hypoxia;GO:0001892//embryonic placenta development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0033235//positive regulation of protein sumoylation;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045821//positive regulation of glycolytic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046886//positive regulation of hormone biosynthetic process"	bHLH
ENSG00000143442	13.948	15.724	16.911	16.737	19.102	17.043	1633	1743	1338	1087	1557	1423	POGZ	pogo transposable element derived with ZNF domain [Source:HGNC Symbol;Acc:HGNC:18801]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051301//cell division;GO:0051382//kinetochore assembly;GO:1905168//positive regulation of double-strand break repair via homologous recombination	--
ENSG00000143443	4.931	5.098	4.54	4.962	4.689	5.723	213.24	221.59	145	158.96	171.33	180.08	C1orf56	chromosome 1 open reading frame 56 [Source:HGNC Symbol;Acc:HGNC:26045]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0042127//regulation of cell population proliferation	--
ENSG00000143450	0.374	0.076	0.218	0.522	0.59	0.07	12.01	6	3	9	13	4	OAZ3	ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0072562//blood microparticle	GO:0005515//protein binding;GO:0008073//ornithine decarboxylase inhibitor activity	GO:0006596//polyamine biosynthetic process;GO:0007283//spermatogenesis;GO:0043086//negative regulation of catalytic activity;GO:0045732//positive regulation of protein catabolic process;GO:0050790//regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport;GO:1902268//negative regulation of polyamine transmembrane transport	--
ENSG00000143452	0	0	0	0	0	0	0	0	0	0	0	0	HORMAD1	HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding	GO:0001824//blastocyst development;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042138//meiotic DNA double-strand break formation;GO:0048477//oogenesis;GO:0051177//meiotic sister chromatid cohesion;GO:0051321//meiotic cell cycle;GO:0051598//meiotic recombination checkpoint signaling;GO:0060629//regulation of homologous chromosome segregation	--
ENSG00000143457	13.229	13.364	12.569	9.542	11.641	10.563	832	843	559	458	625	498	GOLPH3L	golgi phosphoprotein 3 like [Source:HGNC Symbol;Acc:HGNC:24882]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0031985//Golgi cisterna;GO:0032580//Golgi cisterna membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0070273//phosphatidylinositol-4-phosphate binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0043001//Golgi to plasma membrane protein transport;GO:0048194//Golgi vesicle budding;GO:0050714//positive regulation of protein secretion"	--
ENSG00000143458	1.045	1.336	1.118	0.639	1.244	0.498	91.06	107	63	57	66	48	GABPB2	GA binding protein transcription factor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:28441]	-	-	-	-	GO:0005634//nucleus	GO:0000976//transcription cis-regulatory region binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0045944//positive regulation of transcription by RNA polymerase II	Others
ENSG00000143469	1.215	0.772	0.556	1.207	1.156	0.735	183	108	76	107	133	80	SYT14	synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000143473	0.04	0.05	0.018	0	0	0	4	7	2	0	0	0	KCNH1	potassium voltage-gated channel subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:6250]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008289//lipid binding;GO:1902936//phosphatidylinositol bisphosphate binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007520//myoblast fusion;GO:0034765//regulation of ion transmembrane transport;GO:0042127//regulation of cell population proliferation;GO:0042391//regulation of membrane potential;GO:0048015//phosphatidylinositol-mediated signaling;GO:0055085//transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071805//potassium ion transmembrane transport	--
ENSG00000143476	1.52	1.61	1.022	0.472	0.531	0.466	139	148	69	32	41	31	DTL	denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0031965//nuclear membrane;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0000209//protein polyubiquitination;GO:0006260//DNA replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0009411//response to UV;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0019985//translesion synthesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle	--
ENSG00000143479	3.489	3.955	3.164	2.411	3.627	4.071	310	341	226	159	209	226	DYRK3	dual specificity tyrosine phosphorylation regulated kinase 3 [Source:HGNC Symbol;Acc:HGNC:3094]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010494//cytoplasmic stress granule;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030218//erythrocyte differentiation;GO:0035063//nuclear speck organization;GO:0035617//stress granule disassembly;GO:0043066//negative regulation of apoptotic process;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0051301//cell division;GO:0080135//regulation of cellular response to stress;GO:1902751//positive regulation of cell cycle G2/M phase transition;GO:1903008//organelle disassembly;GO:1903432//regulation of TORC1 signaling"	--
ENSG00000143486	19.716	23.086	20.352	20.912	21.228	22.241	820	960	627	633	717	675	EIF2D	eukaryotic translation initiation factor 2D [Source:HGNC Symbol;Acc:HGNC:6583]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0038023//signaling receptor activity	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0006886//intracellular protein transport;GO:0032790//ribosome disassembly;GO:0075522//IRES-dependent viral translational initiation	--
ENSG00000143493	3.607	3.963	3.441	2.678	2.956	3.576	317	323	212	172	196	215	INTS7	integrator complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:24484]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0006974//cellular response to DNA damage stimulus;GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing;GO:0071479//cellular response to ionizing radiation	--
ENSG00000143494	0.758	0.667	0.969	0.815	0.306	0.222	66	49	57	22	21	15	VASH2	vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0000768//syncytium formation by plasma membrane fusion;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006508//proteolysis;GO:0045765//regulation of angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0060674//placenta blood vessel development;GO:0060711//labyrinthine layer development;GO:0060716//labyrinthine layer blood vessel development;GO:0061564//axon development;GO:0140253//cell-cell fusion	--
ENSG00000143498	1.497	1.231	1.683	1.227	1.432	1.63	61	49	44	36	43	40	TAF1A	"TATA-box binding protein associated factor, RNA polymerase I subunit A [Source:HGNC Symbol;Acc:HGNC:11532]"	-	-	-	-	GO:0000120//RNA polymerase I transcription regulator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006360//transcription by RNA polymerase I;GO:0006366//transcription by RNA polymerase II	--
ENSG00000143499	9.698	10.06	9.614	8.504	8.306	7.404	351	366	257	228	254	195	SMYD2	SET and MYND domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20982]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11426;K11426	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000993//RNA polymerase II complex binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010452//histone H3-K36 methylation;GO:0016571//histone methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:1901796//regulation of signal transduction by p53 class mediator"	--
ENSG00000143502	0.639	0.425	0.274	1.312	1.609	0.658	28	22	5	46	57	21	SUSD4	sushi domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25470]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045087//innate immune response;GO:0045957//negative regulation of complement activation, alternative pathway;GO:0045959//negative regulation of complement activation, classical pathway"	--
ENSG00000143507	3.639	3.746	4.846	2.873	2.676	3.663	179	190	158	100	114	134	DUSP10	dual specificity phosphatase 10 [Source:HGNC Symbol;Acc:HGNC:3065]	Environmental Information Processing;Environmental Information Processing;Cellular Processes	Signal transduction;Signal transduction;Cell growth and death	ko04010//MAPK signaling pathway;ko04013//MAPK signaling pathway - fly;ko04214//Apoptosis - fly	K20216;K20216;K20216	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0008432//JUN kinase binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0002819//regulation of adaptive immune response;GO:0006470//protein dephosphorylation;GO:0010033//response to organic substance;GO:0010633//negative regulation of epithelial cell migration;GO:0016311//dephosphorylation;GO:0030336//negative regulation of cell migration;GO:0032496//response to lipopolysaccharide;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0043508//negative regulation of JUN kinase activity;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045088//regulation of innate immune response;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0046329//negative regulation of JNK cascade;GO:0048709//oligodendrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090335//regulation of brown fat cell differentiation;GO:1903753//negative regulation of p38MAPK cascade;GO:1905042//negative regulation of epithelium regeneration;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000143512	0	0	0	0.051	0	0	0	0	0	2	0	0	HHIPL2	HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842]	-	-	-	-	GO:0005576//extracellular region	GO:0003824//catalytic activity;GO:0005515//protein binding	-	--
ENSG00000143514	20.852	19.315	20.31	16.433	19.048	19.079	1867	1774	1332	1140	1428	1242	TP53BP2	tumor protein p53 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:12000]	Environmental Information Processing	Signal transduction	ko04390//Hippo signaling pathway	K16823	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0042802//identical protein binding;GO:0051059//NF-kappaB binding	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0045786//negative regulation of cell cycle;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1900119//positive regulation of execution phase of apoptosis	--
ENSG00000143515	7.443	7.567	7.771	6.767	7.596	7.455	883	897	699	614	736	638	ATP8B2	ATPase phospholipid transporting 8B2 [Source:HGNC Symbol;Acc:HGNC:13534]	-	-	-	-	GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090554//phosphatidylcholine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140345//phosphatidylcholine flippase activity	GO:0006869//lipid transport;GO:0007030//Golgi organization;GO:0015914//phospholipid transport;GO:0034204//lipid translocation;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation	--
ENSG00000143520	0	0	0	0	0	0	0	0	0	0	0	0	FLG2	filaggrin family member 2 [Source:HGNC Symbol;Acc:HGNC:33276]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0036457//keratohyalin granule;GO:1904724//tertiary granule lumen	GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0007155//cell adhesion;GO:0048730//epidermis morphogenesis;GO:0061436//establishment of skin barrier	--
ENSG00000143536	0	0	0	0	0	0	0	0	0	0	0	0	CRNN	cornulin [Source:HGNC Symbol;Acc:HGNC:1230]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0009408//response to heat;GO:0010468//regulation of gene expression;GO:0010838//positive regulation of keratinocyte proliferation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071345//cellular response to cytokine stimulus;GO:0098609//cell-cell adhesion;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000143537	50.451	54.167	50.841	69.153	70.366	58.782	2965	3195	2202	3004	3494	2508	ADAM15	ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005929//cilium;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001953//negative regulation of cell-matrix adhesion;GO:0002418//immune response to tumor cell;GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008584//male gonad development;GO:0022617//extracellular matrix disassembly;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030574//collagen catabolic process;GO:0042246//tissue regeneration;GO:0045087//innate immune response;GO:0060317//cardiac epithelial to mesenchymal transition;GO:1900121//negative regulation of receptor binding;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:1990910//response to hypobaric hypoxia	--
ENSG00000143543	97.658	90.556	102.309	95.919	87.275	105.054	2560.92	2388.12	1991.17	1856.69	1944.06	2012.18	JTB	jumping translocation breakpoint [Source:HGNC Symbol;Acc:HGNC:6201]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody	GO:0019901//protein kinase binding	GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0045860//positive regulation of protein kinase activity;GO:0051301//cell division	--
ENSG00000143545	42.679	44.812	40.103	37.915	37.975	34.893	1030.91	1087.49	715.1	679.3	774.61	612.97	RAB13	"RAB13, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9762]"	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06109	GO:0005768//endosome;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032593//insulin-responsive compartment;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0010737//protein kinase A signaling;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0017157//regulation of exocytosis;GO:0030866//cortical actin cytoskeleton organization;GO:0031175//neuron projection development;GO:0032456//endocytic recycling;GO:0032869//cellular response to insulin stimulus;GO:0035767//endothelial cell chemotaxis;GO:0044795//trans-Golgi network to recycling endosome transport;GO:0048210//Golgi vesicle fusion to target membrane;GO:0070830//bicellular tight junction assembly;GO:0072659//protein localization to plasma membrane;GO:0097368//establishment of Sertoli cell barrier	--
ENSG00000143546	0	0	0	0	0.699	0	0	0	0	0	5	0	S100A8	S100 calcium binding protein A8 [Source:HGNC Symbol;Acc:HGNC:10498]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21127	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0045111//intermediate filament cytoskeleton;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0035662//Toll-like receptor 4 binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050544//arachidonic acid binding;GO:0050786//RAGE receptor binding	GO:0002376//immune system process;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002526//acute inflammatory response;GO:0002544//chronic inflammatory response;GO:0002793//positive regulation of peptide secretion;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0010043//response to zinc ion;GO:0014002//astrocyte development;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0030307//positive regulation of cell growth;GO:0030593//neutrophil chemotaxis;GO:0032119//sequestering of zinc ion;GO:0032496//response to lipopolysaccharide;GO:0035425//autocrine signaling;GO:0042060//wound healing;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0045471//response to ethanol;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051493//regulation of cytoskeleton organization;GO:0070488//neutrophil aggregation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000143549	70.946	70.524	65.879	68.195	68.762	64.309	2523	2523	1730	1772	1974	1618	TPM3	tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system;Cancer: specific types	ko05200//Pathways in cancer;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05216//Thyroid cancer	K09290;K09290;K09290;K09290;K09290;K09290	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005862//muscle thin filament tropomyosin;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization	--
ENSG00000143552	0	0	0	0	0	0	0	0	0	0	0	0	NUP210L	nucleoporin 210 like [Source:HGNC Symbol;Acc:HGNC:29915]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14314;K14314	GO:0005643//nuclear pore;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000143553	20.909	22.524	20.891	20.181	19.116	22.395	435	471	321	311	336	339	SNAPIN	SNAP associated protein [Source:HGNC Symbol;Acc:HGNC:17145]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030672//synaptic vesicle membrane;GO:0031083//BLOC-1 complex;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex;GO:1904115//axon cytoplasm	GO:0000149//SNARE binding;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0007040//lysosome organization;GO:0007042//lysosomal lumen acidification;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0008089//anterograde axonal transport;GO:0008090//retrograde axonal transport;GO:0008333//endosome to lysosome transport;GO:0010977//negative regulation of neuron projection development;GO:0016079//synaptic vesicle exocytosis;GO:0016188//synaptic vesicle maturation;GO:0031175//neuron projection development;GO:0031503//protein-containing complex localization;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0032418//lysosome localization;GO:0032438//melanosome organization;GO:0043393//regulation of protein binding;GO:0048489//synaptic vesicle transport;GO:0048490//anterograde synaptic vesicle transport;GO:0051036//regulation of endosome size;GO:0051604//protein maturation;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule;GO:0072553//terminal button organization;GO:0097352//autophagosome maturation;GO:1902774//late endosome to lysosome transport;GO:1902824//positive regulation of late endosome to lysosome transport;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000143554	1.325	1.662	2.19	2.465	1.696	1.904	64.02	81	61	90.11	70	60	SLC27A3	solute carrier family 27 member 3 [Source:HGNC Symbol;Acc:HGNC:10997]	Human Diseases	Endocrine and metabolic disease	ko04931//Insulin resistance	K08772	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport	--
ENSG00000143556	0	0.112	0	0	1.064	0	0	1	0	0	8	0	S100A7	S100 calcium binding protein A7 [Source:HGNC Symbol;Acc:HGNC:10497]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21126	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0035578//azurophil granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050786//RAGE receptor binding	GO:0000302//response to reactive oxygen species;GO:0001525//angiogenesis;GO:0008544//epidermis development;GO:0010820//positive regulation of T cell chemotaxis;GO:0030216//keratinocyte differentiation;GO:0032496//response to lipopolysaccharide;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0051238//sequestering of metal ion;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071624//positive regulation of granulocyte chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000143569	83.409	90.757	85.297	83.608	80.721	88.733	3763	3892	2796	2783	3336	2816	UBAP2L	ubiquitin associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:29877]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0031519//PcG protein complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007339//binding of sperm to zona pellucida;GO:0034063//stress granule assembly;GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000143570	64.414	65.516	72.027	72.251	62.552	72.849	2739	2809	2260	2283	2259	2255	SLC39A1	solute carrier family 39 member 1 [Source:HGNC Symbol;Acc:HGNC:12876]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14709;K14709	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0022890//inorganic cation transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0001701//in utero embryonic development;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0030001//metal ion transport;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0055085//transmembrane transport;GO:0060173//limb development;GO:0071577//zinc ion transmembrane transport	--
ENSG00000143575	36.071	36.984	36.748	46.801	35.695	43.167	816	853	622	795	685	719	HAX1	HCLS1 associated protein X-1 [Source:HGNC Symbol;Acc:HGNC:16915]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0030027//lamellipodium;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0019966//interleukin-1 binding;GO:0047485//protein N-terminus binding	GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030833//regulation of actin filament polymerization;GO:0030854//positive regulation of granulocyte differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0071345//cellular response to cytokine stimulus;GO:1903146//regulation of autophagy of mitochondrion;GO:1903214//regulation of protein targeting to mitochondrion;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000143578	3.732	4.269	3.359	5.101	3.145	3.498	129	133	79	128	86	73	CREB3L4	cAMP responsive element binding protein 3 like 4 [Source:HGNC Symbol;Acc:HGNC:18854]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006986//response to unfolded protein;GO:0007283//spermatogenesis;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000143590	0.849	0.581	0.864	0.86	0.628	0.62	32	22	24.05	24	20	17	EFNA3	ephrin A3 [Source:HGNC Symbol;Acc:HGNC:3223]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0007267//cell-cell signaling;GO:0007411//axon guidance;GO:0016525//negative regulation of angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	--
ENSG00000143595	0	0	0	0	0	0	0	0	0	0	0	0	AQP10	aquaporin 10 [Source:HGNC Symbol;Acc:HGNC:16029]	-	-	-	-	GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015267//channel activity	GO:0006833//water transport;GO:0009636//response to toxic substance;GO:0015793//glycerol transport;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0071468//cellular response to acidic pH;GO:0071918//urea transmembrane transport	--
ENSG00000143603	0.105	0.107	0.147	0.05	0.067	0.061	18	16	9	10	10	12	KCNN3	potassium calcium-activated channel subfamily N member 3 [Source:HGNC Symbol;Acc:HGNC:6292]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko04911//Insulin secretion;ko04929//GnRH secretion	K04944;K04944	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0005242//inward rectifier potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000143612	82.069	75.051	80.012	80.811	76.471	88.519	2643	2442	1894	1920	2104	2006	C1orf43	chromosome 1 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:29876]	-	-	-	-	GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006909//phagocytosis	--
ENSG00000143614	8.088	7.407	7.038	6.325	7.206	6.945	787	840	601	515	603	630	GATAD2B	GATA zinc finger domain containing 2B [Source:HGNC Symbol;Acc:HGNC:30778]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016581//NuRD complex;GO:0016607//nuclear speck;GO:0032991//protein-containing complex"	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031492//nucleosomal DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000736//regulation of stem cell differentiation"	zf-GATA
ENSG00000143621	62.831	65.735	66.133	56.873	57.45	57.006	2415	2539	1873	1619	1865	1594	ILF2	interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000143622	22.163	19.245	20.488	20.743	16.8	18.932	843	715	558	541	602	537	RIT1	Ras like without CAAX 1 [Source:HGNC Symbol;Acc:HGNC:10023]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction	--
ENSG00000143624	9.999	10.564	9.993	11.238	12.199	11.103	902.98	874	664	649.89	882	713	INTS3	integrator complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26153]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032039//integrator complex;GO:0035861//site of double-strand break;GO:0070876//SOSS complex	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0016180//snRNA processing;GO:0044818//mitotic G2/M transition checkpoint	--
ENSG00000143627	0	0	0	0	0	0	0	0	0	0	0	0	PKLR	pyruvate kinase L/R [Source:HGNC Symbol;Acc:HGNC:9020]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism;Human Diseases;Metabolism;Human Diseases	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Endocrine and metabolic disease;Carbohydrate metabolism;Endocrine and metabolic disease	ko01100//Metabolic pathways;ko04932//Non-alcoholic fatty liver disease;ko04910//Insulin signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis;ko04930//Type II diabetes mellitus;ko00620//Pyruvate metabolism;ko04950//Maturity onset diabetes of the young	K12406;K12406;K12406;K12406;K12406;K12406;K12406;K12406;K12406	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004743//pyruvate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030955//potassium ion binding;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0005975//carbohydrate metabolic process;GO:0006096//glycolytic process;GO:0006754//ATP biosynthetic process;GO:0007584//response to nutrient;GO:0008152//metabolic process;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0010038//response to metal ion;GO:0010226//response to lithium ion;GO:0016310//phosphorylation;GO:0032869//cellular response to insulin stimulus;GO:0033198//response to ATP;GO:0042866//pyruvate biosynthetic process;GO:0051591//response to cAMP;GO:0071872//cellular response to epinephrine stimulus	--
ENSG00000143630	0.766	0.737	0.493	0.594	0.877	1.001	61	59	29	35	59	58	HCN3	hyperpolarization activated cyclic nucleotide gated potassium channel 3 [Source:HGNC Symbol;Acc:HGNC:19183]	Organismal Systems	Endocrine system	ko04929//GnRH secretion	K04956	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0044316//cone cell pedicle;GO:0045202//synapse;GO:0098855//HCN channel complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0030552//cAMP binding	GO:0003254//regulation of membrane depolarization;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071805//potassium ion transmembrane transport;GO:0072718//response to cisplatin;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098907//regulation of SA node cell action potential;GO:1903351//cellular response to dopamine;GO:2001257//regulation of cation channel activity	--
ENSG00000143631	0.015	0.007	0	0.107	0.027	0.005	4	2	0	21	6	1	FLG	filaggrin [Source:HGNC Symbol;Acc:HGNC:3748]	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005829//cytosol;GO:0036457//keratohyalin granule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0062023//collagen-containing extracellular matrix	GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0061436//establishment of skin barrier	--
ENSG00000143632	0.136	0.303	0	0.262	0	0.044	4	9	0	6	0	1	ACTA1	"actin alpha 1, skeletal muscle [Source:HGNC Symbol;Acc:HGNC:129]"	-	-	-	-	GO:0001725//stress fiber;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0005869//dynactin complex;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0030017//sarcomere;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0044297//cell body;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0000166//nucleotide binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0017022//myosin binding;GO:0043531//ADP binding	GO:0006936//muscle contraction;GO:0009612//response to mechanical stimulus;GO:0009991//response to extracellular stimulus;GO:0010226//response to lithium ion;GO:0010628//positive regulation of gene expression;GO:0030240//skeletal muscle thin filament assembly;GO:0043503//skeletal muscle fiber adaptation;GO:0048545//response to steroid hormone;GO:0048741//skeletal muscle fiber development;GO:0071417//cellular response to organonitrogen compound;GO:0090131//mesenchyme migration	--
ENSG00000143633	5.077	4.881	4.243	3.3	4.308	5.366	150	148	93	71	108	117	C1orf131	chromosome 1 open reading frame 131 [Source:HGNC Symbol;Acc:HGNC:25332]	-	-	-	-	GO:0005694//chromosome	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000143641	32.472	35.884	32.646	27.665	30.5	26.247	2979	3309	2212	1880	2364	1752	GALNT2	polypeptide N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4124]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine;GO:0051604//protein maturation	--
ENSG00000143643	4.994	5.029	5.114	4.165	4.971	5.133	320	308	210	188	244	240	TTC13	tetratricopeptide repeat domain 13 [Source:HGNC Symbol;Acc:HGNC:26204]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000143653	32.741	32.664	33.66	31.95	30.598	34.043	1454	1458	1104	1051	1148	1100	SCCPDH	saccharopine dehydrogenase (putative) [Source:HGNC Symbol;Acc:HGNC:24275]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody;GO:0031093//platelet alpha granule lumen	GO:0016491//oxidoreductase activity	GO:0009247//glycolipid biosynthetic process	--
ENSG00000143669	3.439	1.888	1.861	2.329	2.678	1.716	583	332	213	159	239	235	LYST	lysosomal trafficking regulator [Source:HGNC Symbol;Acc:HGNC:1968]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006909//phagocytosis;GO:0007040//lysosome organization;GO:0008104//protein localization;GO:0015031//protein transport;GO:0030595//leukocyte chemotaxis;GO:0032438//melanosome organization;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0033364//mast cell secretory granule organization;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0043473//pigmentation;GO:0051607//defense response to virus	--
ENSG00000143674	2.437	2.035	1.748	1.576	2.076	2.037	262	225	155	134	183	148	MAP3K21	mitogen-activated protein kinase kinase kinase 21 [Source:HGNC Symbol;Acc:HGNC:29798]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0046777//protein autophosphorylation	--
ENSG00000143702	15.363	11.02	11.428	5.68	9.587	9.366	1632	1111	752	546	850	743	CEP170	centrosomal protein 170 [Source:HGNC Symbol;Acc:HGNC:28920]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding	-	--
ENSG00000143727	56.269	56.061	62.03	58.743	53.282	67.299	1630	1606	1247	1252	1271	1358	ACP1	acid phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:122]	Metabolism;Human Diseases;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cellular community - eukaryotes;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04520//Adherens junction;ko00730//Thiamine metabolism;ko00740//Riboflavin metabolism	K14394;K14394;K14394;K14394;K14394	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0070062//extracellular exosome	GO:0003993//acid phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000143740	15.808	17.519	17.501	15.487	19.679	20.076	809.62	924.13	684.81	633.33	771.54	702.41	SNAP47	synaptosome associated protein 47 [Source:HGNC Symbol;Acc:HGNC:30669]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031083//BLOC-1 complex;GO:0031201//SNARE complex;GO:0032279//asymmetric synapse;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0016082//synaptic vesicle priming;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0060291//long-term synaptic potentiation;GO:0098967//exocytic insertion of neurotransmitter receptor to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse	--
ENSG00000143742	145.194	142.023	147.992	135.603	118.539	155.691	4457	4362	3174	3058	3084	3233	SRP9	signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03109	"GO:0005737//cytoplasm;GO:0005785//signal recognition particle receptor complex;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0048500//signal recognition particle"	GO:0003723//RNA binding;GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0008312//7S RNA binding	GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0045900//negative regulation of translational elongation	--
ENSG00000143748	6.805	4.979	6.014	3.819	5.111	4.268	364	300	209	170	208	174	NVL	nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14571	GO:0000176//nuclear exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:1990275//preribosome binding	GO:0006364//rRNA processing;GO:0032092//positive regulation of protein binding;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0051973//positive regulation of telomerase activity;GO:1904749//regulation of protein localization to nucleolus	--
ENSG00000143751	4.559	4.8	5.337	4.375	4.752	4.304	377	399	326	268	332	259	SDE2	SDE2 telomere maintenance homolog [Source:HGNC Symbol;Acc:HGNC:26643]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0016485//protein processing;GO:0016567//protein ubiquitination;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0034644//cellular response to UV;GO:0051301//cell division	--
ENSG00000143753	43.846	41.733	44.203	37.912	36.62	42.424	1848	1768	1376	1156	1304	1301	DEGS1	"delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709]"	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04712;K04712;K04712	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0035579//specific granule membrane	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0042284//sphingolipid delta-4 desaturase activity;GO:0050251//retinol isomerase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0022900//electron transport chain;GO:0030148//sphingolipid biosynthetic process;GO:0043217//myelin maintenance;GO:0046513//ceramide biosynthetic process	--
ENSG00000143756	12.763	10.711	9.141	6.773	8.611	7.071	1261	1116	680	543	678	561	FBXO28	F-box protein 28 [Source:HGNC Symbol;Acc:HGNC:29046]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome"	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000209//protein polyubiquitination	--
ENSG00000143761	163.62	170.745	171.311	179.162	178.735	166.868	6250	6561	4834	5068	5767	4636	ARF1	ADP ribosylation factor 1 [Source:HGNC Symbol;Acc:HGNC:652]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway;ko05134//Legionellosis;ko05110//Vibrio cholerae infection	K07937;K07937;K07937;K07937;K07937;K07937;K07937	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019904//protein domain specific binding	GO:0002090//regulation of receptor internalization;GO:0006878//cellular copper ion homeostasis;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0060292//long-term synaptic depression;GO:0097061//dendritic spine organization;GO:0098586//cellular response to virus;GO:1990386//mitotic cleavage furrow ingression	--
ENSG00000143768	5.584	5.047	2.475	0.258	0.444	0.683	235	213.99	77	8	15.92	21	LEFTY2	left-right determination factor 2 [Source:HGNC Symbol;Acc:HGNC:3122]	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04668;K04668	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction	--
ENSG00000143771	14.148	16.964	16.712	16.585	12.939	19.933	962	991	717	623	720	837	CNIH4	cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	GO:0005515//protein binding;GO:0031730//CCR5 chemokine receptor binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000143772	47.785	49.85	54.908	52.142	50.414	49.691	6092	6355	5196	4865	5448	4564	ITPKB	inositol-trisphosphate 3-kinase B [Source:HGNC Symbol;Acc:HGNC:6179]	Metabolism;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00911;K00911;K00911;K00911	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0000828//inositol hexakisphosphate kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity"	GO:0000165//MAPK cascade;GO:0001932//regulation of protein phosphorylation;GO:0002262//myeloid cell homeostasis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0016310//phosphorylation;GO:0030217//T cell differentiation;GO:0032957//inositol trisphosphate metabolic process;GO:0032958//inositol phosphate biosynthetic process;GO:0033030//negative regulation of neutrophil apoptotic process;GO:0035726//common myeloid progenitor cell proliferation;GO:0045059//positive thymic T cell selection;GO:0045061//thymic T cell selection;GO:0045638//negative regulation of myeloid cell differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0071277//cellular response to calcium ion	--
ENSG00000143774	102.684	107.877	111.285	126.202	114.298	111.089	2183	2248	1742	1977	1951	1710	GUK1	guanylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:4693]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00942;K00942	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006163//purine nucleotide metabolic process;GO:0006185//dGDP biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process	--
ENSG00000143776	4.711	3.57	3.635	2.261	3.649	2.913	967	679	491	334	544	447	CDC42BPA	CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0030027//lamellipodium;GO:0031252//cell leading edge;GO:0042641//actomyosin;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018107//peptidyl-threonine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization	--
ENSG00000143786	0.627	0.453	0.154	0.41	0.674	0.418	33	24	6	16	30	16	CNIH3	cornichon family AMPA receptor auxiliary protein 3 [Source:HGNC Symbol;Acc:HGNC:26802]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032281//AMPA glutamate receptor complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	GO:0016192//vesicle-mediated transport;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000143793	6.204	6.841	6.578	6.559	6.105	5.496	166	184	130	130	138	107	C1orf35	chromosome 1 open reading frame 35 [Source:HGNC Symbol;Acc:HGNC:19032]	-	-	-	-	GO:0005576//extracellular region;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000143797	20.736	19.703	24.72	17.655	15.309	18.731	1786	1494	1243	1078	1203	1215	MBOAT2	membrane bound O-acyltransferase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25193]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13517;K13517;K13517	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0106262//1-acylglycerophosphoethanolamine O-acyltransferase activity;GO:0106263//1-acylglycerophosphoserine O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0030258//lipid modification;GO:0032330//regulation of chondrocyte differentiation;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling	--
ENSG00000143799	32.329	33.246	35.824	32.379	33.111	31.51	2667	2758	2182	1979	2305	1891	PARP1	poly(ADP-ribose) polymerase 1 [Source:HGNC Symbol;Acc:HGNC:270]	Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Genetic Information Processing	Cardiovascular disease;Signal transduction;Cell growth and death;Cell growth and death;Replication and repair	ko05415//Diabetic cardiomyopathy;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko04210//Apoptosis;ko03410//Base excision repair	K24070;K24070;K24070;K24070;K24070	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0035861//site of double-strand break;GO:0043229//intracellular organelle;GO:0090734//site of DNA damage"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030331//estrogen receptor binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051287//NAD binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412//R-SMAD binding;GO:0140294//NAD DNA ADP-ribosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006366//transcription by RNA polymerase II;GO:0006471//protein ADP-ribosylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007005//mitochondrion organization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010332//response to gamma radiation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010990//regulation of SMAD protein complex assembly;GO:0016540//protein autoprocessing;GO:0018312//peptidyl-serine ADP-ribosylation;GO:0018424//peptidyl-glutamic acid poly-ADP-ribosylation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030225//macrophage differentiation;GO:0030592//DNA ADP-ribosylation;GO:0032042//mitochondrial DNA metabolic process;GO:0032869//cellular response to insulin stimulus;GO:0032880//regulation of protein localization;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0034599//cellular response to oxidative stress;GO:0034644//cellular response to UV;GO:0036211//protein modification process;GO:0043504//mitochondrial DNA repair;GO:0044030//regulation of DNA methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0051901//positive regulation of mitochondrial depolarization;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0071294//cellular response to zinc ion;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1900182//positive regulation of protein localization to nucleus;GO:1901216//positive regulation of neuron death;GO:1903376//regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903518//positive regulation of single strand break repair;GO:1904044//response to aldosterone;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904646//cellular response to amyloid-beta;GO:1904762//positive regulation of myofibroblast differentiation;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:1990966//ATP generation from poly-ADP-D-ribose;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2001170//negative regulation of ATP biosynthetic process	--
ENSG00000143801	14.898	11.975	12.176	16.997	16.414	16.786	497.09	549.23	405.24	406.16	448.5	409.74	PSEN2	presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04722//Neurotrophin signaling pathway;ko04330//Notch signaling pathway	K04522;K04522;K04522;K04522	GO:0000139//Golgi membrane;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005743//mitochondrial inner membrane;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0030426//growth cone;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0035253//ciliary rootlet;GO:0043025//neuronal cell body;GO:0043198//dendritic shaft;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070765//gamma-secretase complex	"GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving"	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006816//calcium ion transport;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0016485//protein processing;GO:0034205//amyloid-beta formation;GO:0035556//intracellular signal transduction;GO:0042987//amyloid precursor protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0050435//amyloid-beta metabolic process;GO:0110097//regulation of calcium import into the mitochondrion;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000143811	17.208	15.715	19.506	18.142	19.555	19.524	582.74	540	489.05	456	562	481.21	PYCR2	pyrroline-5-carboxylate reductase 2 [Source:HGNC Symbol;Acc:HGNC:30262]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism	K00286;K00286;K00286	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004735//pyrroline-5-carboxylate reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006561//proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0034599//cellular response to oxidative stress;GO:0055129//L-proline biosynthetic process	--
ENSG00000143815	8.281	6.939	7.746	5.799	7.155	7.643	575	526	403	320	433	424	LBR	lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K19532;K19532	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	"GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050613//delta14-sterol reductase activity;GO:0070087//chromo shadow domain binding;GO:0070402//NADPH binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0030223//neutrophil differentiation	--
ENSG00000143816	1.637	1.665	1.646	1.43	1.453	1.704	136	139	101	88	102	103	WNT9A	Wnt family member 9A [Source:HGNC Symbol;Acc:HGNC:12778]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0007275//multicellular organism development;GO:0008285//negative regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0045165//cell fate commitment;GO:0060070//canonical Wnt signaling pathway;GO:0061072//iris morphogenesis;GO:0061303//cornea development in camera-type eye;GO:0071300//cellular response to retinoic acid;GO:0072498//embryonic skeletal joint development	--
ENSG00000143819	46.629	46.474	50.298	55.451	49.421	51.946	1552	1560	1227	1370	1394	1278	EPHX1	epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401]	Human Diseases;Human Diseases;Organismal Systems;Metabolism;Human Diseases	Cancer: overview;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts	K01253;K01253;K01253;K01253;K01253	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0004301//epoxide hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033961//cis-stilbene-oxide hydrolase activity	GO:0006629//lipid metabolic process;GO:0006725//cellular aromatic compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0014070//response to organic cyclic compound;GO:0019369//arachidonic acid metabolic process;GO:0019439//aromatic compound catabolic process;GO:0097176//epoxide metabolic process	--
ENSG00000143839	0	0.066	0	0	0	0	0	2	0	0	0	0	REN	renin [Source:HGNC Symbol;Acc:HGNC:9958]	Human Diseases;Organismal Systems;Organismal Systems	Cardiovascular disease;Endocrine system;Endocrine system	ko05415//Diabetic cardiomyopathy;ko04924//Renin secretion;ko04614//Renin-angiotensin system	K01380;K01380;K01380	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045177//apical part of cell	GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0002003//angiotensin maturation;GO:0002016//regulation of blood volume by renin-angiotensin;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0006508//proteolysis;GO:0008217//regulation of blood pressure;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009755//hormone-mediated signaling pathway;GO:0010033//response to organic substance;GO:0032496//response to lipopolysaccharide;GO:0035902//response to immobilization stress;GO:0042756//drinking behavior;GO:0043408//regulation of MAPK cascade;GO:0048469//cell maturation;GO:0050435//amyloid-beta metabolic process;GO:0051591//response to cAMP;GO:0070305//response to cGMP;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000143842	2.181	1.527	1.933	1.701	2.139	2.843	143	117	113	100	139	120	SOX13	SRY-box transcription factor 13 [Source:HGNC Symbol;Acc:HGNC:11192]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0030154//cell differentiation;GO:0042492//gamma-delta T cell differentiation;GO:0045165//cell fate commitment;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090336//positive regulation of brown fat cell differentiation"	HMG
ENSG00000143845	11.02	10.838	12.706	12.664	11.251	11.272	565	558	450	462	487	401	ETNK2	ethanolamine kinase 2 [Source:HGNC Symbol;Acc:HGNC:25575]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K00894;K00894	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004305//ethanolamine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001701//in utero embryonic development;GO:0001890//placenta development;GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008150//biological_process;GO:0008654//phospholipid biosynthetic process;GO:0009791//post-embryonic development;GO:0016310//phosphorylation;GO:0035264//multicellular organism growth	--
ENSG00000143847	0.576	0.834	0.517	1.156	0.878	0.544	77	94	49	74	86	51	PPFIA4	PTPRF interacting protein alpha 4 [Source:HGNC Symbol;Acc:HGNC:9248]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009986//cell surface;GO:0045202//synapse;GO:0048786//presynaptic active zone	GO:0005515//protein binding	GO:0050808//synapse organization	--
ENSG00000143850	14.601	14.8	13.5	12.865	12.45	11.44	1799	1904	1303	1196	1349	1075	PLEKHA6	pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000143851	0.036	0	0	0	0.021	0	2	0	0	0	1	0	PTPN7	protein tyrosine phosphatase non-receptor type 7 [Source:HGNC Symbol;Acc:HGNC:9659]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K18019	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0072686//mitotic spindle	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0000165//MAPK cascade;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000143858	0.025	0.038	0.034	0.017	0.045	0.017	4	6	4.01	2.01	6.01	2	SYT2	synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0042584//chromaffin granule membrane;GO:0045202//synapse;GO:0070382//exocytic vesicle	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0046872//metal ion binding"	GO:0007269//neurotransmitter secretion;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0030154//cell differentiation;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000143862	24.909	22.226	22.619	27.521	26.495	29.525	924	829	619	756	830	797	ARL8A	ADP ribosylation factor like GTPase 8A [Source:HGNC Symbol;Acc:HGNC:25192]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K07955	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0051233//spindle midzone;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0051301//cell division	--
ENSG00000143867	0.025	0.101	0.137	0.034	0.299	0.07	1	4	4	1	10	2	OSR1	odd-skipped related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:8111]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001655//urogenital system development;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001823//mesonephros development;GO:0002062//chondrocyte differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008406//gonad development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030857//negative regulation of epithelial cell differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0042474//middle ear morphogenesis;GO:0042476//odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048389//intermediate mesoderm development;GO:0048793//pronephros development;GO:0048863//stem cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0072075//metanephric mesenchyme development;GO:0072111//cell proliferation involved in kidney development;GO:0072133//metanephric mesenchyme morphogenesis;GO:0072143//mesangial cell development;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072166//posterior mesonephric tubule development;GO:0072168//specification of anterior mesonephric tubule identity;GO:0072169//specification of posterior mesonephric tubule identity;GO:0072180//mesonephric duct morphogenesis;GO:0072183//negative regulation of nephron tubule epithelial cell differentiation;GO:0072184//renal vesicle progenitor cell differentiation;GO:0072190//ureter urothelium development;GO:0072207//metanephric epithelium development;GO:0072208//metanephric smooth muscle tissue development;GO:0072234//metanephric nephron tubule development;GO:0072239//metanephric glomerulus vasculature development;GO:0072259//metanephric interstitial fibroblast development;GO:0072268//pattern specification involved in metanephros development;GO:0072498//embryonic skeletal joint development;GO:0090094//metanephric cap mesenchymal cell proliferation involved in metanephros development;GO:1905408//negative regulation of creatine transmembrane transporter activity;GO:2000543//positive regulation of gastrulation;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	zf-C2H2
ENSG00000143869	0.12	0.083	0.035	0.028	0	0	23	16	5	4	0	0	GDF7	growth differentiation factor 7 [Source:HGNC Symbol;Acc:HGNC:4222]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Development and regeneration;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04360//Axon guidance;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K20013;K20013;K20013;K20013	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding	"GO:0007411//axon guidance;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0021509//roof plate formation;GO:0021527//spinal cord association neuron differentiation;GO:0021915//neural tube development;GO:0022612//gland morphogenesis;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0030901//midbrain development;GO:0032924//activin receptor signaling pathway;GO:0045165//cell fate commitment;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048608//reproductive structure development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048853//forebrain morphogenesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0060571//morphogenesis of an epithelial fold;GO:2001051//positive regulation of tendon cell differentiation"	--
ENSG00000143870	132.955	138.094	125.652	140.881	137.433	135.283	6285.53	6564	4386.84	4935.53	5489.3	4652.98	PDIA6	protein disulfide isomerase family A member 6 [Source:HGNC Symbol;Acc:HGNC:30168]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09584	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034663//endoplasmic reticulum chaperone complex;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016853//isomerase activity	GO:0006457//protein folding	--
ENSG00000143878	98.643	98.767	109.816	92.061	96.145	95.458	4843	4874	3982	3348	3988	3410	RHOB	ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K07856	GO:0005634//nucleus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding	GO:0000281//mitotic cytokinesis;GO:0001525//angiogenesis;GO:0006886//intracellular protein transport;GO:0006915//apoptotic process;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0008333//endosome to lysosome transport;GO:0008360//regulation of cell shape;GO:0010595//positive regulation of endothelial cell migration;GO:0015031//protein transport;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043065//positive regulation of apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0045786//negative regulation of cell cycle;GO:0061154//endothelial tube morphogenesis;GO:0070301//cellular response to hydrogen peroxide;GO:0071479//cellular response to ionizing radiation	--
ENSG00000143882	6.053	5.677	6.977	7.998	10.059	7.468	364.47	333	331.16	324.47	474.7	352.02	ATP6V1C2	ATPase H+ transporting V1 subunit C2 [Source:HGNC Symbol;Acc:HGNC:18264]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0016241//regulation of macroautophagy;GO:0030177//positive regulation of Wnt signaling pathway;GO:1902600//proton transmembrane transport	--
ENSG00000143889	16.602	14.662	16.043	14.192	14.808	13.495	994	850	681	607	688	611	HNRNPLL	heterogeneous nuclear ribonucleoprotein L like [Source:HGNC Symbol;Acc:HGNC:25127]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0033120//positive regulation of RNA splicing;GO:0043484//regulation of RNA splicing	--
ENSG00000143891	7.919	8.551	7.76	8.73	6.967	8.197	374	389	266	267	278	273	GALM	galactose mutarotase [Source:HGNC Symbol;Acc:HGNC:24063]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00010//Glycolysis / Gluconeogenesis;ko00052//Galactose metabolism	K01785;K01785;K01785	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004034//aldose 1-epimerase activity;GO:0016853//isomerase activity;GO:0030246//carbohydrate binding	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006012//galactose metabolic process;GO:0019318//hexose metabolic process;GO:0033499//galactose catabolic process via UDP-galactose	--
ENSG00000143919	4.715	3.8	4.79	4.735	4.925	5.529	147	103	110	110	117	123	CAMKMT	calmodulin-lysine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:26276]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K18826;K18826	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018025//calmodulin-lysine N-methyltransferase activity;GO:0031072//heat shock protein binding	GO:0006479//protein methylation;GO:0007005//mitochondrion organization;GO:0018022//peptidyl-lysine methylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0032259//methylation	--
ENSG00000143921	0	0.007	0	0.009	0.016	0	0	1	0	1	2	0	ABCG8	ATP binding cassette subfamily G member 8 [Source:HGNC Symbol;Acc:HGNC:13887]	Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems	Digestive system;Digestive system;Membrane transport;Digestive system	ko04976//Bile secretion;ko04979//Cholesterol metabolism;ko02010//ABC transporters;ko04975//Fat digestion and absorption	K05684;K05684;K05684;K05684	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0120020//cholesterol transfer activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0010949//negative regulation of intestinal phytosterol absorption;GO:0014850//response to muscle activity;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0030299//intestinal cholesterol absorption;GO:0031667//response to nutrient levels;GO:0033344//cholesterol efflux;GO:0038183//bile acid signaling pathway;GO:0042632//cholesterol homeostasis;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0055085//transmembrane transport;GO:0055092//sterol homeostasis;GO:0070328//triglyceride homeostasis;GO:0120009//intermembrane lipid transfer	--
ENSG00000143924	7.405	6.521	5.803	4.583	5.514	6.375	816	682	478	387	496	512	EML4	EMAP like 4 [Source:HGNC Symbol;Acc:HGNC:1316]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05223//Non-small cell lung cancer	K15420;K15420;K15420	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0072686//mitotic spindle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051301//cell division	--
ENSG00000143933	201.068	197.24	194.598	189.241	177.51	185.792	5046	4975	3606	3516	3765	3396	CALM2	calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0005955//calcineurin complex;GO:0008076//voltage-gated potassium channel complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0034704//calcium channel complex;GO:0043209//myelin sheath;GO:1902494//catalytic complex;GO:1990722//DAPK1-calmodulin complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0010856//adenylate cyclase activator activity;GO:0016301//kinase activity;GO:0019855//calcium channel inhibitor activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030234//enzyme regulator activity;GO:0031432//titin binding;GO:0031997//N-terminal myristoylation domain binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0072542//protein phosphatase activator activity;GO:0097718//disordered domain specific binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0002027//regulation of heart rate;GO:0002834//regulation of response to tumor cell;GO:0005513//detection of calcium ion;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0021762//substantia nigra development;GO:0031279//regulation of cyclase activity;GO:0031954//positive regulation of protein autophosphorylation;GO:0032465//regulation of cytokinesis;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0046777//protein autophosphorylation;GO:0050848//regulation of calcium-mediated signaling;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051592//response to calcium ion;GO:0055117//regulation of cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071805//potassium ion transmembrane transport;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1904094//positive regulation of autophagic cell death;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905913//negative regulation of calcium ion export across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane	--
ENSG00000143942	1.657	0.66	0.698	1.293	0.567	1.012	45	18	14	26	13	20	CHAC2	ChaC glutathione specific gamma-glutamylcyclotransferase 2 [Source:HGNC Symbol;Acc:HGNC:32363]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K07232;K07232	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003839//gamma-glutamylcyclotransferase activity;GO:0016829//lyase activity;GO:0061928//glutathione specific gamma-glutamylcyclotransferase activity	GO:0006750//glutathione biosynthetic process;GO:0006751//glutathione catabolic process;GO:0008150//biological_process	--
ENSG00000143947	292.573	295.861	295.291	285.302	244.879	252.662	4770	4846	3554	3446	3373	2996	RPS27A	ribosomal protein S27a [Source:HGNC Symbol;Acc:HGNC:10417]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Cellular Processes	"Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Folding, sorting and degradation;Translation;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05171//Coronavirus disease - COVID-19;ko05012//Parkinson disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04120//Ubiquitin mediated proteolysis;ko03010//Ribosome;ko04137//Mitophagy - animal	K02977;K02977;K02977;K02977;K02977;K02977;K02977;K02977	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0030666//endocytic vesicle membrane;GO:0031982//vesicle;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process	--
ENSG00000143951	4.571	3.027	3.051	3.329	3.483	3.956	284.82	236.89	168.49	149.13	188.19	187.69	WDPCP	WD repeat containing planar cell polarity effector [Source:HGNC Symbol;Acc:HGNC:28027]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0042995//cell projection;GO:0097541//axonemal basal plate	GO:0005515//protein binding	GO:0001736//establishment of planar polarity;GO:0001822//kidney development;GO:0002093//auditory receptor cell morphogenesis;GO:0007224//smoothened signaling pathway;GO:0007399//nervous system development;GO:0010762//regulation of fibroblast migration;GO:0016476//regulation of embryonic cell shape;GO:0021915//neural tube development;GO:0030030//cell projection organization;GO:0032185//septin cytoskeleton organization;GO:0032880//regulation of protein localization;GO:0042073//intraciliary transport;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0043587//tongue morphogenesis;GO:0044782//cilium organization;GO:0045184//establishment of protein localization;GO:0048568//embryonic organ development;GO:0051893//regulation of focal adhesion assembly;GO:0055123//digestive system development;GO:0060021//roof of mouth development;GO:0060271//cilium assembly;GO:0060541//respiratory system development;GO:0072359//circulatory system development;GO:0090521//glomerular visceral epithelial cell migration;GO:1900027//regulation of ruffle assembly;GO:1902017//regulation of cilium assembly;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000143952	10.42	7.452	7.935	8.098	7.396	9.706	971	687	547	549	581	573	VPS54	VPS54 subunit of GARP complex [Source:HGNC Symbol;Acc:HGNC:18652]	-	-	-	-	GO:0000938//GARP complex;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006896//Golgi to vacuole transport;GO:0007041//lysosomal transport;GO:0015031//protein transport;GO:0040008//regulation of growth;GO:0042147//retrograde transport, endosome to Golgi;GO:0048873//homeostasis of number of cells within a tissue;GO:0050881//musculoskeletal movement;GO:0060052//neurofilament cytoskeleton organization"	--
ENSG00000143954	0	0	0	0	0.13	0	0	0	0	0	2	0	REG3G	regenerating family member 3 gamma [Source:HGNC Symbol;Acc:HGNC:29595]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0042834//peptidoglycan binding;GO:0070492//oligosaccharide binding	GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0008284//positive regulation of cell population proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0043434//response to peptide hormone;GO:0044278//cell wall disruption in other organism;GO:0045617//negative regulation of keratinocyte differentiation;GO:0050830//defense response to Gram-positive bacterium;GO:0051838//cytolysis by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090303//positive regulation of wound healing	--
ENSG00000143970	4.759	4.472	3.988	3.453	3.434	3.94	968	816	503	423	576	520	ASXL2	ASXL transcriptional regulator 2 [Source:HGNC Symbol;Acc:HGNC:23805]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035517//PR-DUB complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0009887//animal organ morphogenesis;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000143971	3.142	2.531	2.197	2.014	2.342	2.604	318	252	167	154	195	191	ETAA1	ETAA1 activator of ATR kinase [Source:HGNC Symbol;Acc:HGNC:24648]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043596//nuclear replication fork	GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000143977	17.196	13.42	19.825	20.066	20.335	24.92	214	168	181	185	212	224	SNRPG	small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11099	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005683//U7 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034719//SMN-Sm protein complex;GO:0043186//P granule;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071004//U2-type prespliceosome;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0097526//spliceosomal tri-snRNP complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000143994	0.58	0.104	0.667	0.155	0.435	0.791	11	3	9	3	9	13	ABHD1	abhydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17553]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008126//acetylesterase activity;GO:0016787//hydrolase activity;GO:0034338//short-chain carboxylesterase activity;GO:0047372//acylglycerol lipase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0008150//biological_process;GO:0044255//cellular lipid metabolic process;GO:0051792//medium-chain fatty acid biosynthetic process;GO:0051793//medium-chain fatty acid catabolic process	--
ENSG00000143995	5.157	5.699	5.132	4.761	5.084	5.539	380	424	288	257	328	284	MEIS1	Meis homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7000]	Human Diseases;Cellular Processes	Cancer: overview;Cellular community - eukaryotes	ko05202//Transcriptional misregulation in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells	K15613;K15613	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001525//angiogenesis;GO:0001654//eye development;GO:0002089//lens morphogenesis in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0030097//hemopoiesis;GO:0035855//megakaryocyte development;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0060216//definitive hemopoiesis"	Homeobox
ENSG00000144010	0.245	0.087	0.316	0.106	0.156	0.12	8.37	3	8	2.68	4.52	3	TRIM43B	tripartite motif containing 43B [Source:HGNC Symbol;Acc:HGNC:37146]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000144015	0.046	0.339	0	0.051	0.218	0.039	1.63	12	0	1.32	6.48	1	TRIM43	tripartite motif containing 43 [Source:HGNC Symbol;Acc:HGNC:19015]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000144021	23.122	23.088	24.117	22.931	24.649	26.184	1903	1910	1466	1398	1714	1568	CIAO1	cytosolic iron-sulfur assembly component 1 [Source:HGNC Symbol;Acc:HGNC:14280]	-	-	-	-	GO:0005737//cytoplasm;GO:0071817//MMXD complex;GO:0097361//CIA complex	GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007059//chromosome segregation;GO:0008284//positive regulation of cell population proliferation;GO:0016226//iron-sulfur cluster assembly;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000144026	3.09	3.169	2.615	2.725	3.679	3.147	250.98	228	176	172.43	246.94	207.61	ZNF514	zinc finger protein 514 [Source:HGNC Symbol;Acc:HGNC:25894]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000144028	56.108	58.727	60.348	52.827	55.606	54.685	8317	8685	6491	5839	6995	5841	SNRNP200	small nuclear ribonucleoprotein U5 subunit 200 [Source:HGNC Symbol;Acc:HGNC:30859]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12854	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016020//membrane;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	"GO:0000354//cis assembly of pre-catalytic spliceosome;GO:0000388//spliceosome conformational change to release U4 (or U4atac) and U1 (or U11);GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0016043//cellular component organization;GO:0090304//nucleic acid metabolic process"	--
ENSG00000144029	0.064	0	0	0.234	0.103	0.057	7.32	0	0	20.48	10.34	4.95	MRPS5	mitochondrial ribosomal protein S5 [Source:HGNC Symbol;Acc:HGNC:14498]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	-	--
ENSG00000144031	0.373	0.432	0.557	0.335	0.421	0.485	14	16	16	10	14	14	ANKRD53	ankyrin repeat domain 53 [Source:HGNC Symbol;Acc:HGNC:25691]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0031116//positive regulation of microtubule polymerization;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:1902412//regulation of mitotic cytokinesis	--
ENSG00000144034	6.817	6.316	6.635	6.258	4.874	5.965	102	92	71	68	61	62	TPRKB	TP53RK binding protein [Source:HGNC Symbol;Acc:HGNC:24259]	-	-	-	-	GO:0000408//EKC/KEOPS complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0000722//telomere maintenance via recombination;GO:0002949//tRNA threonylcarbamoyladenosine modification;GO:0008033//tRNA processing	--
ENSG00000144035	0	0	0.06	0	0	0	0	0	1	0	0	0	NAT8	N-acetyltransferase 8 (putative) [Source:HGNC Symbol;Acc:HGNC:18069]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K20838;K20838	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	"GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047198//cysteine-S-conjugate N-acetyltransferase activity"	GO:0006749//glutathione metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0018003//peptidyl-lysine N6-acetylation;GO:0043066//negative regulation of apoptotic process;GO:0050435//amyloid-beta metabolic process;GO:1990000//amyloid fibril formation	--
ENSG00000144036	6.651	6.026	5.504	4.604	4.726	4.969	803	742	480	418	489	443	EXOC6B	exocyst complex component 6B [Source:HGNC Symbol;Acc:HGNC:17085]	-	-	-	-	GO:0000145//exocyst	GO:0005515//protein binding	GO:0000281//mitotic cytokinesis;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000144040	3.229	3.204	3.143	2.626	3.901	3.369	216	220	186	136	246	181	SFXN5	sideroflexin 5 [Source:HGNC Symbol;Acc:HGNC:16073]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0015137//citrate transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0015746//citrate transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000144043	42.157	46.138	45.938	43.016	40.645	45.197	2718.88	2994	2126.93	2207	2396.78	2230	TEX261	testis expressed 261 [Source:HGNC Symbol;Acc:HGNC:30712]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0097020//COPII receptor activity	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006897//endocytosis	--
ENSG00000144045	0	0	0.039	0	0	0	0	0	1	0	0	0	DQX1	DEAQ-box RNA dependent ATPase 1 [Source:HGNC Symbol;Acc:HGNC:20410]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex	GO:0000166//nucleotide binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0032508//DNA duplex unwinding	--
ENSG00000144048	9.663	10.332	7.974	8.67	9.284	8.684	316	343	197	214	261	212	DUSP11	dual specificity phosphatase 11 [Source:HGNC Symbol;Acc:HGNC:3066]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0045171//intercellular bridge	"GO:0003723//RNA binding;GO:0004651//polynucleotide 5'-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides"	GO:0006396//RNA processing;GO:0006470//protein dephosphorylation;GO:0016070//RNA metabolic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0098507//polynucleotide 5' dephosphorylation	--
ENSG00000144057	0.298	0.219	0.141	0.44	0.504	0.292	42	31	13	46	60	30	ST6GAL2	"ST6 beta-galactoside alpha-2,6-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10861]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00514//Other types of O-glycan biosynthesis	K00779;K00779;K00779	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003824//catalytic activity;GO:0003835//beta-galactoside alpha-2,6-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation	--
ENSG00000144061	3.057	3.06	3.162	1.82	2.525	3.686	134	129	104	55	98	80	NPHP1	nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0005929//cilium;GO:0016020//membrane;GO:0030054//cell junction;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0007632//visual behavior;GO:0030030//cell projection organization;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0048515//spermatid differentiation;GO:0060041//retina development in camera-type eye;GO:0090251//protein localization involved in establishment of planar polarity;GO:0098609//cell-cell adhesion;GO:1903348//positive regulation of bicellular tight junction assembly	--
ENSG00000144063	1.269	1.072	0.884	1.264	1.405	0.972	61	45	31	45	51	34	MALL	"mal, T cell differentiation protein like [Source:HGNC Symbol;Acc:HGNC:6818]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath	GO:0042552//myelination;GO:0042632//cholesterol homeostasis	--
ENSG00000144115	13.337	14.807	14.041	16.45	16.348	15.175	485	528	379	441	509	396	THNSL2	threonine synthase like 2 [Source:HGNC Symbol;Acc:HGNC:25602]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005125//cytokine activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0070905//serine binding	GO:0007165//signal transduction;GO:0008150//biological_process;GO:0009071//serine family amino acid catabolic process;GO:0016311//dephosphorylation;GO:0046360//2-oxobutyrate biosynthetic process	--
ENSG00000144118	18.523	17.232	17.553	19.197	18.131	18.83	750	714	525	539	650	573	RALB	RAS like proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:9840]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer	K07835;K07835;K07835;K07835;K07835;K07835	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0031625//ubiquitin protein ligase binding;GO:0051117//ATPase binding	GO:0001928//regulation of exocyst assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0009267//cellular response to starvation;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0051301//cell division;GO:0060178//regulation of exocyst localization;GO:0071360//cellular response to exogenous dsRNA;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000144119	0	0	0	0	0	0	0	0	0	0	0	0	C1QL2	complement C1q like 2 [Source:HGNC Symbol;Acc:HGNC:24181]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000144120	3.261	2.85	4.024	5.384	3.427	5.232	86	81	83	112	79	106	TMEM177	transmembrane protein 177 [Source:HGNC Symbol;Acc:HGNC:28143]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding	-	--
ENSG00000144130	0	0	0	0	0	0	0	0	0	0	0	0	NT5DC4	5'-nucleotidase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:27678]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	-	GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000144134	7.061	7.072	7.702	5.847	4.824	7.372	262.31	267.34	189.45	161.2	176.56	175.82	RABL2A	"RAB, member of RAS oncogene family like 2A [Source:HGNC Symbol;Acc:HGNC:9799]"	-	-	-	-	GO:0012505//endomembrane system	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport	--
ENSG00000144136	12.722	14.363	13.494	12.158	12.153	12.461	863	928	648	517	647	565	SLC20A1	solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0005316//high-affinity inorganic phosphate:sodium symporter activity;GO:0005436//sodium:phosphate symporter activity;GO:0015293//symporter activity;GO:0038023//signaling receptor activity	GO:0006796//phosphate-containing compound metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0031214//biomineral tissue development;GO:0035435//phosphate ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0055085//transmembrane transport	--
ENSG00000144152	0.212	0.239	0.287	0.403	0.302	0.133	6	6	4	8	10	4	FBLN7	fibulin 7 [Source:HGNC Symbol;Acc:HGNC:26740]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0031012//extracellular matrix	GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0007155//cell adhesion;GO:0110151//positive regulation of biomineralization	--
ENSG00000144161	0.712	0.513	0.609	0.563	0.455	0.708	87	63	55	51	47	63	ZC3H8	zinc finger CCCH-type containing 8 [Source:HGNC Symbol;Acc:HGNC:30941]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0035327//transcriptionally active chromatin;GO:0035363//histone locus body	"GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III;GO:0043029//T cell homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0046677//response to antibiotic;GO:0070245//positive regulation of thymocyte apoptotic process"	--
ENSG00000144182	2.686	2.722	2.105	2.409	2.753	2.146	71	76	37	47	63	43	LIPT1	lipoyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:29569]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00785//Lipoic acid metabolism	K10105;K10105	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0017118//lipoyltransferase activity	GO:0006464//cellular protein modification process;GO:0006629//lipid metabolic process;GO:0009249//protein lipoylation;GO:0019752//carboxylic acid metabolic process	--
ENSG00000144191	0.077	0.057	0.026	0	0	0	4	3	1	0	0	0	CNGA3	cyclic nucleotide gated channel subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:2150]	Organismal Systems;Environmental Information Processing	Sensory system;Signal transduction	ko04740//Olfactory transduction;ko04024//cAMP signaling pathway	K04950;K04950	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043204//perikaryon;GO:0097386//glial cell projection;GO:1902495//transmembrane transporter complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0015276//ligand-gated ion channel activity;GO:0030553//cGMP binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0031960//response to corticosteroid;GO:0032026//response to magnesium ion;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0051591//response to cAMP;GO:0055085//transmembrane transport;GO:0098659//inorganic cation import across plasma membrane	--
ENSG00000144199	7.118	7.766	9.496	8.838	8.158	6.865	200.52	217.49	197.51	185.8	193.79	139.42	FAHD2B	fumarylacetoacetate hydrolase domain containing 2B [Source:HGNC Symbol;Acc:HGNC:25318]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	-	--
ENSG00000144214	0	0.19	0	0	0.113	0.131	0	4	0	0	2	2	LYG1	lysozyme g1 [Source:HGNC Symbol;Acc:HGNC:27014]	-	-	-	-	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process;GO:0009253//peptidoglycan catabolic process;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000144218	6.625	6.038	5.505	6.938	8.342	7.132	810	756	512	695	931	748	AFF3	AF4/FMR2 family member 3 [Source:HGNC Symbol;Acc:HGNC:6473]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032783//super elongation complex;GO:0043227//membrane-bounded organelle	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0034612//response to tumor necrosis factor;GO:0035116//embryonic hindlimb morphogenesis"	AF-4
ENSG00000144224	59.99	49.786	46.654	30.476	33.87	43.048	4138	3591	2430	1598	2112	2165	UBXN4	UBX domain protein 4 [Source:HGNC Symbol;Acc:HGNC:14860]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K24348	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	GO:0006986//response to unfolded protein;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000144227	0.071	0.071	0.072	0.144	0.126	0.122	4	4	3	6	6	5	NXPH2	neurexophilin 2 [Source:HGNC Symbol;Acc:HGNC:8076]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005102//signaling receptor binding	GO:0007218//neuropeptide signaling pathway	--
ENSG00000144228	5.129	3.477	4.062	3.06	3.71	3.456	596	439	317	246	332	294	SPOPL	speckle type BTB/POZ protein like [Source:HGNC Symbol;Acc:HGNC:27934]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K10523	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0016567//protein ubiquitination;GO:0030162//regulation of proteolysis;GO:0031397//negative regulation of protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000144229	0.016	0.024	0.011	0	0	0	2	3	1	0	0	0	THSD7B	thrombospondin type 1 domain containing 7B [Source:HGNC Symbol;Acc:HGNC:29348]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0031532//actin cytoskeleton reorganization	--
ENSG00000144230	0.072	0.041	0.032	0.332	0.048	0.123	3	1	1	6	1	3	GPR17	G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0033612//receptor serine/threonine kinase binding	GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0048709//oligodendrocyte differentiation;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000144231	9.203	10.94	10.17	5.516	8.247	7.591	513	566	392	285	365	305	POLR2D	RNA polymerase II subunit D [Source:HGNC Symbol;Acc:HGNC:9191]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03012;K03012	"GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030880//RNA polymerase complex;GO:0043231//intracellular membrane-bounded organelle"	GO:0000166//nucleotide binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0034402//recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex;GO:0044237//cellular metabolic process;GO:0045948//positive regulation of translational initiation"	--
ENSG00000144233	6.199	5.773	6.999	5.48	5.225	7.256	601	562	500	390	430	511	AMMECR1L	AMMECR1 like [Source:HGNC Symbol;Acc:HGNC:28658]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000144278	8.38	6.882	7.248	6.833	6.547	4.812	912	698	522	510	537	402	GALNT13	polypeptide N-acetylgalactosaminyltransferase 13 [Source:HGNC Symbol;Acc:HGNC:23242]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine	--
ENSG00000144283	58.155	57.146	56.211	51.945	51.673	54.814	5449	5385	3807	3510	3945	3721	PKP4	plakophilin 4 [Source:HGNC Symbol;Acc:HGNC:9026]	-	-	-	-	GO:0000922//spindle pole;GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0030496//midbody;GO:0044291//cell-cell contact zone;GO:0048471//perinuclear region of cytoplasm;GO:0051233//spindle midzone;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0030155//regulation of cell adhesion;GO:0032467//positive regulation of cytokinesis;GO:0043547//positive regulation of GTPase activity;GO:0098609//cell-cell adhesion	--
ENSG00000144285	0	0	0.018	0	0.005	0	0	0	1	0	1	0	SCN1A	sodium voltage-gated channel alpha subunit 1 [Source:HGNC Symbol;Acc:HGNC:10585]	Organismal Systems	Nervous system	ko04728//Dopaminergic synapse	K04833	GO:0001518//voltage-gated sodium channel complex;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0030424//axon;GO:0033268//node of Ranvier;GO:0034706//sodium channel complex;GO:0043025//neuronal cell body;GO:0043194//axon initial segment	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity	GO:0001508//action potential;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007628//adult walking behavior;GO:0019227//neuronal action potential propagation;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050884//neuromuscular process controlling posture;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0055085//transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000144290	1.33	0.767	0.762	0.315	0.343	0.454	114	79	56	27	27	33	SLC4A10	solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0097440//apical dendrite;GO:0097441//basal dendrite;GO:0097442//CA3 pyramidal cell dendrite;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0005452//inorganic anion exchanger activity;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0006885//regulation of pH;GO:0007601//visual perception;GO:0009416//response to light stimulus;GO:0009791//post-embryonic development;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0021860//pyramidal neuron development;GO:0030641//regulation of cellular pH;GO:0035264//multicellular organism growth;GO:0035641//locomotory exploration behavior;GO:0035725//sodium ion transmembrane transport;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048854//brain morphogenesis;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000144306	15.392	8.568	9.829	8.376	11.668	13.526	546	395	314	258	352	357	SCRN3	secernin 3 [Source:HGNC Symbol;Acc:HGNC:30382]	-	-	-	-	-	GO:0016805//dipeptidase activity;GO:0070004//cysteine-type exopeptidase activity	GO:0006508//proteolysis	--
ENSG00000144320	10.302	7.791	10.748	7.883	7.115	9.265	947	686	580	458	537	519	LNPK	"lunapark, ER junction formation factor [Source:HGNC Symbol;Acc:HGNC:21610]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0071782//endoplasmic reticulum tubular network;GO:0098826//endoplasmic reticulum tubular network membrane	GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007029//endoplasmic reticulum organization;GO:0007596//blood coagulation;GO:0032330//regulation of chondrocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0060173//limb development;GO:0071786//endoplasmic reticulum tubular network organization;GO:0071788//endoplasmic reticulum tubular network maintenance;GO:1903373//positive regulation of endoplasmic reticulum tubular network organization	--
ENSG00000144331	0.091	0	0	0.068	0	0.051	4	0	0	1	0	2	ZNF385B	zinc finger protein 385B [Source:HGNC Symbol;Acc:HGNC:26332]	-	-	-	-	GO:0005634//nucleus	GO:0002039//p53 binding;GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	zf-C2H2
ENSG00000144339	0.962	1.076	0.653	1.163	1.589	1.89	56	63	28	50	78	80	TMEFF2	transmembrane protein with EGF like and two follistatin like domains 2 [Source:HGNC Symbol;Acc:HGNC:11867]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0030336//negative regulation of cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0044319//wound healing, spreading of cells;GO:0045720//negative regulation of integrin biosynthetic process;GO:0051497//negative regulation of stress fiber assembly"	--
ENSG00000144354	0.209	0.498	0.168	0.516	0.289	0.38	12	19	7	16	7	10	CDCA7	cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0042127//regulation of cell population proliferation"	--
ENSG00000144355	0.023	0	0	0	0	0	1	0	0	0	0	0	DLX1	distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009954//proximal/distal pattern formation;GO:0021544//subpallium development;GO:0021766//hippocampus development;GO:0021879//forebrain neuron differentiation;GO:0021892//cerebral cortex GABAergic interneuron differentiation;GO:0021893//cerebral cortex GABAergic interneuron fate commitment;GO:0030154//cell differentiation;GO:0030514//negative regulation of BMP signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043524//negative regulation of neuron apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0048706//embryonic skeletal system development;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071773//cellular response to BMP stimulus;GO:1902871//positive regulation of amacrine cell differentiation;GO:1903845//negative regulation of cellular response to transforming growth factor beta stimulus"	Homeobox
ENSG00000144357	9.628	7.777	8.089	6.045	6.689	7.335	1519	1188	863	705	862	832	UBR3	ubiquitin protein ligase E3 component n-recognin 3 [Source:HGNC Symbol;Acc:HGNC:30467]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001967//suckling behavior;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007608//sensory perception of smell;GO:0009792//embryo development ending in birth or egg hatching;GO:0016567//protein ubiquitination;GO:0071596//ubiquitin-dependent protein catabolic process via the N-end rule pathway	--
ENSG00000144362	2.08	1.752	2.112	1.804	2.319	2.673	47	37.69	35.42	30.85	47.72	43.97	PHOSPHO2	"phosphatase, orphan 2 [Source:HGNC Symbol;Acc:HGNC:28316]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00750//Vitamin B6 metabolism	K13248;K13248	-	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033883//pyridoxal phosphatase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000144366	46.506	35.74	40.028	36.094	36.747	40.37	2744	1945	1703	1468	1591	1675	GULP1	GULP PTB domain containing engulfment adaptor 1 [Source:HGNC Symbol;Acc:HGNC:18649]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0006869//lipid transport;GO:0006909//phagocytosis;GO:0006911//phagocytosis, engulfment;GO:0006915//apoptotic process"	--
ENSG00000144369	6.57	4.871	3.747	2.794	3.356	3.804	781	582	329	246	337	329	FAM171B	family with sequence similarity 171 member B [Source:HGNC Symbol;Acc:HGNC:29412]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000144381	204.359	179.585	184.275	164.776	166.768	167.667	9448	8327	6337	5696	6600	5622	HSPD1	heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261]	Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases	"Infectious disease: bacterial;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: bacterial;Endocrine and metabolic disease"	ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko03018//RNA degradation;ko05134//Legionellosis;ko04940//Type I diabetes mellitus	K04077;K04077;K04077;K04077;K04077	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009986//cell surface;GO:0016020//membrane;GO:0030135//coated vesicle;GO:0030141//secretory granule;GO:0032991//protein-containing complex;GO:0046696//lipopolysaccharide receptor complex;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece	GO:0000166//nucleotide binding;GO:0001530//lipopolysaccharide binding;GO:0002039//p53 binding;GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008035//high-density lipoprotein particle binding;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0034185//apolipoprotein binding;GO:0034186//apolipoprotein A-I binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0002842//positive regulation of T cell mediated immune response to tumor cell;GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006986//response to unfolded protein;GO:0008637//apoptotic mitochondrial changes;GO:0009409//response to cold;GO:0032727//positive regulation of interferon-alpha production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0034514//mitochondrial unfolded protein response;GO:0042026//protein refolding;GO:0042100//B cell proliferation;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0043032//positive regulation of macrophage activation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045041//protein import into mitochondrial intermembrane space;GO:0048291//isotype switching to IgG isotypes;GO:0050821//protein stabilization;GO:0050870//positive regulation of T cell activation;GO:0051131//chaperone-mediated protein complex assembly;GO:0051604//protein maturation;GO:0051702//biological process involved in interaction with symbiont	--
ENSG00000144395	0.043	0.037	0	0	0.076	0.018	2	2	0	0	3	1	CCDC150	coiled-coil domain containing 150 [Source:HGNC Symbol;Acc:HGNC:26834]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000144401	13.828	11.498	15.967	12.611	9.321	13.416	344	285	280	236	200	257	METTL21A	"methyltransferase 21A, HSPA lysine [Source:HGNC Symbol;Acc:HGNC:30476]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0051117//ATPase binding	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0032259//methylation	--
ENSG00000144406	0.074	0.099	0.077	0.166	0.098	0.033	21	28	16	29	23	4	UNC80	"unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0034703//cation channel complex	GO:0005261//cation channel activity	GO:0034220//ion transmembrane transport;GO:0055080//cation homeostasis;GO:0098655//cation transmembrane transport	--
ENSG00000144407	0.02	0.097	0.024	0	0	0	1	5	1	0	0	0	PTH2R	parathyroid hormone 2 receptor [Source:HGNC Symbol;Acc:HGNC:9609]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04586	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004991//parathyroid hormone receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000144410	0.077	0.154	0	0.052	0	0.106	2	4	0	1	0	2	CPO	carboxypeptidase O [Source:HGNC Symbol;Acc:HGNC:21011]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000144426	6.832	3.582	4.51	3.167	4.302	4.734	1590	780	679	469	672	647	NBEAL1	neurobeachin like 1 [Source:HGNC Symbol;Acc:HGNC:20681]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0008104//protein localization	--
ENSG00000144445	2.752	2.58	2.938	2.831	1.854	2.459	204.2	174.5	125.69	119.8	119.91	142.56	KANSL1L	KAT8 regulatory NSL complex subunit 1 like [Source:HGNC Symbol;Acc:HGNC:26310]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0044545//NSL complex	GO:0035035//histone acetyltransferase binding	-	--
ENSG00000144451	13.896	11.8	11.656	10.052	10.506	9.935	355	305	224	192	229	187	SPAG16	sperm associated antigen 16 [Source:HGNC Symbol;Acc:HGNC:23225]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:1990716//axonemal central apparatus	GO:0005515//protein binding	GO:0007288//sperm axoneme assembly;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0060271//cilium assembly;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance	--
ENSG00000144452	0	0.01	0	0	0.016	0	0	2	0	0	2	0	ABCA12	ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05646	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0097209//epidermal lamellar body;GO:0097234//epidermal lamellar body membrane	GO:0000166//nucleotide binding;GO:0005102//signaling receptor binding;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0034040//ATPase-coupled lipid transmembrane transporter activity;GO:0034191//apolipoprotein A-I receptor binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140359//ABC-type transporter activity	GO:0003336//corneocyte desquamation;GO:0006672//ceramide metabolic process;GO:0006869//lipid transport;GO:0006886//intracellular protein transport;GO:0010875//positive regulation of cholesterol efflux;GO:0019725//cellular homeostasis;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization;GO:0032379//positive regulation of intracellular lipid transport;GO:0032940//secretion by cell;GO:0033700//phospholipid efflux;GO:0034204//lipid translocation;GO:0035627//ceramide transport;GO:0043129//surfactant homeostasis;GO:0045055//regulated exocytosis;GO:0045616//regulation of keratinocyte differentiation;GO:0048286//lung alveolus development;GO:0055085//transmembrane transport;GO:0055088//lipid homeostasis;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061436//establishment of skin barrier;GO:0072659//protein localization to plasma membrane;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000144455	24.295	25.482	28.175	27.568	25.089	30.31	959	1027	753	797	828	854	SUMF1	sulfatase modifying factor 1 [Source:HGNC Symbol;Acc:HGNC:20376]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K13444	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0120147//Formylglycine-generating oxidase activity;GO:1903135//cupric ion binding	GO:0006687//glycosphingolipid metabolic process;GO:0018158//protein oxidation;GO:0043687//post-translational protein modification	--
ENSG00000144460	0.325	0.277	0.102	0.023	0.034	0	56	48	13	3	5	0	NYAP2	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 [Source:HGNC Symbol;Acc:HGNC:29291]	-	-	-	-	-	GO:0005515//protein binding	GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0048812//neuron projection morphogenesis	--
ENSG00000144468	5.606	5.923	6.135	5.381	8.871	7.269	476	501	406	377	438	360	RHBDD1	rhomboid domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23081]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0044322//endoplasmic reticulum quality control compartment	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0010954//positive regulation of protein processing;GO:0030154//cell differentiation;GO:0031293//membrane protein intracellular domain proteolysis;GO:0033619//membrane protein proteolysis;GO:0034620//cellular response to unfolded protein;GO:0034644//cellular response to UV;GO:0036503//ERAD pathway;GO:0043066//negative regulation of apoptotic process;GO:0043687//post-translational protein modification;GO:0045732//positive regulation of protein catabolic process;GO:0048515//spermatid differentiation;GO:0051047//positive regulation of secretion;GO:1904211//membrane protein proteolysis involved in retrograde protein transport, ER to cytosol"	--
ENSG00000144476	3.559	4.329	3.364	4.707	5.227	4.426	130	146	79	122	108	91	ACKR3	atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04304;K04304	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0004930//G protein-coupled receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019956//chemokine binding;GO:0019957//C-C chemokine binding;GO:0019958//C-X-C chemokine binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008285//negative regulation of cell population proliferation;GO:0019722//calcium-mediated signaling;GO:0021557//oculomotor nerve development;GO:0031623//receptor internalization;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1905322//positive regulation of mesenchymal stem cell migration	--
ENSG00000144481	0	0	0	0	0	0	0	0	0	0	0	0	TRPM8	transient receptor potential cation channel subfamily M member 8 [Source:HGNC Symbol;Acc:HGNC:17961]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04983	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0099604//ligand-gated calcium channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0009266//response to temperature stimulus;GO:0009409//response to cold;GO:0016048//detection of temperature stimulus;GO:0019722//calcium-mediated signaling;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0050951//sensory perception of temperature stimulus;GO:0050955//thermoception;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000144485	2.318	2.444	3.207	2.454	2.226	1.881	70	67	48	52	51	37	HES6	hes family bHLH transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:18254]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K09087	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009952//anterior/posterior pattern specification;GO:0030154//cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000144488	1.537	1.763	0.85	1.198	1.774	1.226	51	78	47	49	57	49	ESPNL	espin like [Source:HGNC Symbol;Acc:HGNC:27937]	-	-	-	-	GO:0005737//cytoplasm;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007605//sensory perception of sound;GO:0051017//actin filament bundle assembly	--
ENSG00000144504	1.016	0.773	0.627	0.643	2.027	1.258	53.65	53	30	18.17	56.69	42.49	ANKMY1	ankyrin repeat and MYND domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20987]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000144524	12.391	13.478	14.255	10.782	12.319	14.315	460	501	363	347	401	357	COPS7B	COP9 signalosome subunit 7B [Source:HGNC Symbol;Acc:HGNC:16760]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0000338//protein deneddylation;GO:0010387//COP9 signalosome assembly;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000144535	8.976	8.33	8.513	9.337	9.106	8.714	568	580	436.01	438	526	408	DIS3L2	DIS3 like 3'-5' exoribonuclease 2 [Source:HGNC Symbol;Acc:HGNC:28648]	-	-	-	-	GO:0000178//exosome (RNase complex);GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005844//polysome	GO:0000175//3'-5'-exoribonuclease activity;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000278//mitotic cell cycle;GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0006402//mRNA catabolic process;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010587//miRNA catabolic process;GO:0019827//stem cell population maintenance;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0051301//cell division;GO:0051306//mitotic sister chromatid separation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1990074//polyuridylation-dependent mRNA catabolic process"	--
ENSG00000144550	0.587	1.05	1.282	0.695	0.804	0.539	23	24	25	16	15	10	CPNE9	copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0030154//cell differentiation;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000144554	0.948	0.947	0.842	0.73	0.504	0.634	86	95	66	49	45	48	FANCD2	FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10891	GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:1990391//DNA repair complex	GO:0005515//protein binding;GO:0070182//DNA polymerase binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007129//homologous chromosome pairing at meiosis;GO:0007276//gamete generation;GO:0010332//response to gamma radiation;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0034599//cellular response to oxidative stress;GO:0036297//interstrand cross-link repair;GO:0045589//regulation of regulatory T cell differentiation;GO:0048854//brain morphogenesis;GO:0050727//regulation of inflammatory response;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0097150//neuronal stem cell population maintenance;GO:1990918//double-strand break repair involved in meiotic recombination;GO:2000348//regulation of CD40 signaling pathway	--
ENSG00000144559	2.578	3.458	3.381	3.326	3.054	3.403	76	96	67	67	70	69	TAMM41	TAM41 mitochondrial translocator assembly and maintenance homolog [Source:HGNC Symbol;Acc:HGNC:25187]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031314//extrinsic component of mitochondrial inner membrane	GO:0004605//phosphatidate cytidylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0032049//cardiolipin biosynthetic process	--
ENSG00000144560	96.536	91.146	96.3	98.51	95.643	101.207	5910.77	6045.1	4411.16	4681.74	5023.17	4856.94	VGLL4	vestigial like family member 4 [Source:HGNC Symbol;Acc:HGNC:28966]	-	-	-	-	GO:0005634//nucleus	GO:0001223//transcription coactivator binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0035331//negative regulation of hippo signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:1903364//positive regulation of cellular protein catabolic process"	--
ENSG00000144566	22.815	22.002	22.834	20.006	17.92	23.975	1148	1119	824	770	772	840	RAB5A	"RAB5A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9783]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Infectious disease: parasitic;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05132//Salmonella infection;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko04145//Phagosome;ko05146//Amoebiasis;ko04962//Vasopressin-regulated water reabsorption	K07887;K07887;K07887;K07887;K07887;K07887;K07887;K07887;K07887	GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032009//early phagosome;GO:0036477//somatodendritic compartment;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus;GO:0045121//membrane raft;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0098559//cytoplasmic side of early endosome membrane;GO:0098842//postsynaptic early endosome;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019001//guanyl nucleotide binding;GO:0019003//GDP binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006909//phagocytosis;GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0036465//synaptic vesicle recycling;GO:0039694//viral RNA genome replication;GO:0045022//early endosome to late endosome transport;GO:0045921//positive regulation of exocytosis;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0051036//regulation of endosome size;GO:0051489//regulation of filopodium assembly;GO:0150093//amyloid-beta clearance by transcytosis;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000785//regulation of autophagosome assembly	--
ENSG00000144567	57.982	63.14	63.619	69.353	64.376	67.992	2813	2915	2182	2453	2632	2462	RETREG2	reticulophagy regulator family member 2 [Source:HGNC Symbol;Acc:HGNC:28450]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000144579	42.749	45.279	48.205	58.248	56.715	47.604	1773	1917	1494	1821	2020	1521	CTDSP1	CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0001933//negative regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0045665//negative regulation of neuron differentiation;GO:0050768//negative regulation of neurogenesis;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000144580	10.562	12.449	14.166	12.479	12.507	13.13	642	692	595	497	597	554	CNOT9	CCR4-NOT transcription complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:10445]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12606	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex;GO:0032991//protein-containing complex	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0030374//nuclear receptor coactivator activity;GO:0042803//protein homodimerization activity	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0007548//sex differentiation;GO:0017148//negative regulation of translation;GO:0019221//cytokine-mediated signaling pathway;GO:0031047//gene silencing by RNA;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000144583	0.344	0.362	0.253	0.186	0.116	0.162	35	37	19	14	10	12	MARCHF4	membrane associated ring-CH-type finger 4 [Source:HGNC Symbol;Acc:HGNC:29269]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000144589	2.667	4.937	4.156	3.528	3.887	3.934	186	280	214	176	241	184	STK11IP	serine/threonine kinase 11 interacting protein [Source:HGNC Symbol;Acc:HGNC:19184]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0008104//protein localization	--
ENSG00000144591	12.762	12.94	15.27	16.081	16.278	12.997	431	419	367	369	410	312	GMPPA	GDP-mannose pyrophosphorylase A [Source:HGNC Symbol;Acc:HGNC:22923]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K00966;K00966;K00966	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0009058//biosynthetic process	--
ENSG00000144596	0	0	0	0	0.015	0	0	0	0	0	2	0	GRIP2	glutamate receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23841]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0035254//glutamate receptor binding	"GO:0007219//Notch signaling pathway;GO:0014824//artery smooth muscle contraction;GO:0015031//protein transport;GO:0045777//positive regulation of blood pressure;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse"	--
ENSG00000144597	5.463	5.627	6.881	6.269	6.598	6.288	485	452	373	348	462	422	EAF1	ELL associated factor 1 [Source:HGNC Symbol;Acc:HGNC:20907]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0032783//super elongation complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge	GO:0003711//transcription elongation regulator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000144619	3.346	2.462	1.283	2.124	1.805	2.612	229	138	86	111	112	120	CNTN4	contactin 4 [Source:HGNC Symbol;Acc:HGNC:2174]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007158//neuron cell-cell adhesion;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007420//brain development;GO:0031175//neuron projection development;GO:0045665//negative regulation of neuron differentiation;GO:0048167//regulation of synaptic plasticity;GO:0070593//dendrite self-avoidance	--
ENSG00000144635	12.94	13.165	10.957	10.789	9.915	10.559	667	672	416	409	429	396	DYNC1LI1	dynein cytoplasmic 1 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:18745]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10416;K10416;K10416	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030286//dynein complex;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane"	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019003//GDP binding;GO:0045504//dynein heavy chain binding	GO:0000226//microtubule cytoskeleton organization;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0051301//cell division;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint	--
ENSG00000144642	2.542	1.706	1.547	1.572	1.441	1.766	323.39	226	157.96	136	175.97	155.96	RBMS3	RNA binding motif single stranded interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:13427]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	GO:0002357//defense response to tumor cell;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000144644	0	0	0	0	0	0	0	0	0	0	0	0	GADL1	glutamate decarboxylase like 1 [Source:HGNC Symbol;Acc:HGNC:27949]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Metabolism of cofactors and vitamins;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00410//beta-Alanine metabolism;ko00770//Pantothenate and CoA biosynthesis;ko00430//Taurine and hypotaurine metabolism	K18966;K18966;K18966;K18966	GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004068//aspartate 1-decarboxylase activity;GO:0004782//sulfinoalanine decarboxylase activity;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding	GO:0019752//carboxylic acid metabolic process	--
ENSG00000144645	21.241	24.06	19.102	12.537	12.991	10.111	1600	1767	1060	656	831	551	OSBPL10	oxysterol binding protein like 10 [Source:HGNC Symbol;Acc:HGNC:16395]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0015918//sterol transport;GO:0036150//phosphatidylserine acyl-chain remodeling	--
ENSG00000144647	20.32	21.293	21.682	21.769	22.307	21.306	1046	1092	846	826	984	813	POMGNT2	"protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) [Source:HGNC Symbol;Acc:HGNC:25902]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K18207;K18207	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0097363//protein O-GlcNAc transferase activity	GO:0001764//neuron migration;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0035269//protein O-linked mannosylation	--
ENSG00000144648	0.149	0.148	0.068	0.068	0.099	0.239	6	8	3	3	5	6	ACKR2	atypical chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1565]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0071345//cellular response to cytokine stimulus	--
ENSG00000144649	0.037	0.137	0.014	0	0.04	0	2	5	1	0	1	0	GASK1A	golgi associated kinase 1A [Source:HGNC Symbol;Acc:HGNC:24485]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005901//caveola;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000144655	5.409	5.912	5.509	5.904	5.302	6.136	355	390	267	287	294	293	CSRNP1	cysteine and serine rich nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:14300]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0009791//post-embryonic development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis"	CSRNP_N
ENSG00000144659	16.229	17.248	17.918	19.043	20.435	21.077	648	722	546	598	703	620	SLC25A38	solute carrier family 25 member 38 [Source:HGNC Symbol;Acc:HGNC:26054]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015187//glycine transmembrane transporter activity	GO:0006783//heme biosynthetic process;GO:0030218//erythrocyte differentiation;GO:1904983//glycine import into mitochondrion	--
ENSG00000144668	1.07	0.346	0.608	0.555	0.713	0.437	65	47	28	67	72	48	ITGA9	integrin subunit alpha 9 [Source:HGNC Symbol;Acc:HGNC:6145]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06585;K06585;K06585;K06585;K06585;K06585;K06585;K06585;K06585	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0030593//neutrophil chemotaxis;GO:0033627//cell adhesion mediated by integrin;GO:0050900//leukocyte migration;GO:0098609//cell-cell adhesion	--
ENSG00000144671	0	0	0	0	0	0	0	0	0	0	0	0	SLC22A14	solute carrier family 22 member 14 [Source:HGNC Symbol;Acc:HGNC:8495]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity;GO:0032217//riboflavin transmembrane transporter activity	GO:0030317//flagellated sperm motility;GO:0032218//riboflavin transport;GO:0048240//sperm capacitation;GO:0055085//transmembrane transport	--
ENSG00000144674	5.07	3.219	2.115	2.019	3.045	3.745	723	486	237	199	403	395	GOLGA4	golgin A4 [Source:HGNC Symbol;Acc:HGNC:4427]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0051020//GTPase binding	GO:0016192//vesicle-mediated transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0045773//positive regulation of axon extension;GO:0048193//Golgi vesicle transport	--
ENSG00000144677	13.428	13.356	14.923	16.317	14.193	15.777	1225	1152	973	971	1072	988	CTDSPL	CTD small phosphatase like [Source:HGNC Symbol;Acc:HGNC:16890]	-	-	-	-	GO:0005634//nucleus;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0008150//biological_process;GO:0016311//dephosphorylation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000144681	2.81	2.292	2.815	1.841	1.321	1.62	156	138	109	71	71	75	STAC	SH3 and cysteine rich domain [Source:HGNC Symbol;Acc:HGNC:11353]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030315//T-tubule;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042383//sarcolemma	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0034605//cellular response to heat;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2001259//positive regulation of cation channel activity	--
ENSG00000144711	32.284	32.289	34.02	33.174	34.048	34.498	4220	4271	3289	3334	3791	3333	IQSEC1	IQ motif and Sec7 domain ArfGEF 1 [Source:HGNC Symbol;Acc:HGNC:29112]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12495	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051549//positive regulation of keratinocyte migration;GO:0060996//dendritic spine development;GO:0120183//positive regulation of focal adhesion disassembly	--
ENSG00000144712	5.702	5.519	7.267	6.059	6.129	5.648	538	513.34	507.29	425.32	491.09	388.63	CAND2	cullin associated and neddylation dissociated 2 (putative) [Source:HGNC Symbol;Acc:HGNC:30689]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding;GO:0017025//TBP-class protein binding	"GO:0010265//SCF complex assembly;GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000144713	283.541	292.039	269.428	282.154	234.985	231.476	4831	4985.66	3402.71	3599.68	3491.91	2857.37	RPL32	ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:10336]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02912;K02912	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000144724	15.222	12.988	12.805	9.259	11.247	11.798	2260	1847	1388	967	1354	1258	PTPRG	protein tyrosine phosphatase receptor type G [Source:HGNC Symbol;Acc:HGNC:9671]	-	-	-	-	GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042802//identical protein binding	GO:0006470//protein dephosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007420//brain development;GO:0010633//negative regulation of epithelial cell migration;GO:0010977//negative regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000144730	27.072	25.771	24.809	15.213	18.901	18.594	4208	4169	3011	1873	2427	2179	IL17RD	interleukin 17 receptor D [Source:HGNC Symbol;Acc:HGNC:17616]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030368//interleukin-17 receptor activity	GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0019221//cytokine-mediated signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway	--
ENSG00000144736	7.505	6.685	7.312	6.243	7.058	6.669	443	356	303	273	352	274	SHQ1	"SHQ1, H/ACA ribonucleoprotein assembly factor [Source:HGNC Symbol;Acc:HGNC:25543]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0000493//box H/ACA snoRNP assembly;GO:0022618//ribonucleoprotein complex assembly;GO:0043065//positive regulation of apoptotic process;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:2000233//negative regulation of rRNA processing	--
ENSG00000144741	10.457	8.626	10.524	10.646	11.368	10.387	335.09	259.92	232.5	265.43	291.44	264.08	SLC25A26	solute carrier family 25 member 26 [Source:HGNC Symbol;Acc:HGNC:20661]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000095//S-adenosyl-L-methionine transmembrane transporter activity	GO:0006811//ion transport;GO:0015805//S-adenosyl-L-methionine transport;GO:1901962//S-adenosyl-L-methionine transmembrane transport	--
ENSG00000144744	24.295	20.496	23.202	17.234	17.194	21.248	1034	882	736	559	605	677	UBA3	ubiquitin like modifier activating enzyme 3 [Source:HGNC Symbol;Acc:HGNC:12470]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10686	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016874//ligase activity;GO:0019781//NEDD8 activating enzyme activity;GO:0019788//NEDD8 transferase activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0000278//mitotic cell cycle;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0007049//cell cycle;GO:0007113//endomitotic cell cycle;GO:0032446//protein modification by small protein conjugation;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation;GO:0051726//regulation of cell cycle	--
ENSG00000144746	82.732	76.218	74.695	60.542	59.846	67.999	3662	3391	2412	1985	2238	2190	ARL6IP5	ADP ribosylation factor like GTPase 6 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:16937]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002037//negative regulation of L-glutamate import across plasma membrane;GO:0006749//glutathione metabolic process;GO:0007611//learning or memory;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0015031//protein transport;GO:0015813//L-glutamate transmembrane transport;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0036475//neuron death in response to oxidative stress;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051051//negative regulation of transport;GO:0071407//cellular response to organic cyclic compound;GO:0072659//protein localization to plasma membrane;GO:0098712//L-glutamate import across plasma membrane	--
ENSG00000144747	6.653	4.046	4.388	2.26	3.934	3.885	689	408	311	191	332	323	TMF1	TATA element modulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:11870]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0050681//androgen receptor binding	GO:0001675//acrosome assembly;GO:0001819//positive regulation of cytokine production;GO:0007286//spermatid development;GO:0007289//spermatid nucleus differentiation;GO:0008584//male gonad development;GO:0010629//negative regulation of gene expression;GO:0030317//flagellated sperm motility;GO:0030521//androgen receptor signaling pathway;GO:0032275//luteinizing hormone secretion;GO:0033327//Leydig cell differentiation;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061136//regulation of proteasomal protein catabolic process;GO:0071407//cellular response to organic cyclic compound;GO:2000845//positive regulation of testosterone secretion	Others
ENSG00000144749	11.47	12.96	12.279	9.657	10.903	11.62	1275.91	1449.08	1008.5	795.57	1024.56	939.92	LRIG1	leucine rich repeats and immunoglobulin like domains 1 [Source:HGNC Symbol;Acc:HGNC:17360]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0007605//sensory perception of sound;GO:0022405//hair cycle process;GO:0032474//otolith morphogenesis;GO:0060384//innervation	--
ENSG00000144771	0	0	0	0	0	0	0	0	0	0	0	0	LRTM1	leucine rich repeats and transmembrane domains 1 [Source:HGNC Symbol;Acc:HGNC:25023]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0048495//Roundabout binding	GO:0007411//axon guidance;GO:0050919//negative chemotaxis	--
ENSG00000144785	52.033	48.382	35.781	44.349	35.43	49.132	624.67	592.25	301.93	376.06	356.49	431.67	CNPY2	novel protein	-	-	-	-	GO:0005783//endoplasmic reticulum	-	-	--
ENSG00000144791	20.451	22.126	24.229	20.423	24.902	23.945	3579	3671	2896	2715	3581	2968	LIMD1	LIM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:6612]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16682;K16682	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016442//RISC complex;GO:0030054//cell junction	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001666//response to hypoxia;GO:0002076//osteoblast development;GO:0006355//regulation of transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0031047//gene silencing by RNA;GO:0033962//P-body assembly;GO:0035195//gene silencing by miRNA;GO:0035331//negative regulation of hippo signaling;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000637//positive regulation of gene silencing by miRNA"	--
ENSG00000144792	0.983	1.028	1.343	0.658	1.288	0.761	110	125	120	59	109	67	ZNF660	zinc finger protein 660 [Source:HGNC Symbol;Acc:HGNC:26720]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000144802	0.735	0.688	0.801	0.581	0.922	1.006	57	56	41	35	54	58	NFKBIZ	NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K14242	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0010468//regulation of gene expression;GO:0050729//positive regulation of inflammatory response;GO:0050852//T cell receptor signaling pathway;GO:2000321//positive regulation of T-helper 17 cell differentiation	--
ENSG00000144810	575.751	581.963	567.351	445.774	554.547	553.458	43607	42364	30549	24994	33409	28951	COL8A1	collagen type VIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2215]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K23455	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005591//collagen type VIII trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0035987//endodermal cell differentiation;GO:0048593//camera-type eye morphogenesis;GO:0050673//epithelial cell proliferation	--
ENSG00000144815	5.512	5.134	5.149	4.154	4.214	4.584	615	593	398	383	406	405	NXPE3	neurexophilin and PC-esterase domain family member 3 [Source:HGNC Symbol;Acc:HGNC:28238]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000144820	0	0	0	0	0	0	0	0	0	0	0	0	ADGRG7	adhesion G protein-coupled receptor G7 [Source:HGNC Symbol;Acc:HGNC:19241]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000144821	0.027	0.039	0.053	0.042	0.028	0.021	4	5	5	4	3	2	MYH15	myosin heavy chain 15 [Source:HGNC Symbol;Acc:HGNC:31073]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0032982//myosin filament;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0002074//extraocular skeletal muscle development	--
ENSG00000144824	3.827	3.857	1.62	0.931	1.205	0.754	426	394	117	71	117	59	PHLDB2	pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0045111//intermediate filament cytoskeleton;GO:0045180//basal cortex	GO:0005515//protein binding;GO:0045296//cadherin binding	"GO:0000226//microtubule cytoskeleton organization;GO:0010470//regulation of gastrulation;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0045184//establishment of protein localization;GO:0051497//negative regulation of stress fiber assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:1903690//negative regulation of wound healing, spreading of epidermal cells;GO:1904261//positive regulation of basement membrane assembly involved in embryonic body morphogenesis"	--
ENSG00000144827	12.217	10.02	11.159	9.547	8.159	11.643	570	544	405	366	351	420	ABHD10	"abhydrolase domain containing 10, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:25656]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0102390//mycophenolic acid acyl-glucuronide esterase activity"	GO:0002084//protein depalmitoylation;GO:0019391//glucuronoside catabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000144834	0	0	0	0	0	0	0	0	0	0	0	0	TAGLN3	transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]	-	-	-	-	GO:0005634//nucleus;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development	--
ENSG00000144837	3.536	3.492	3.539	3.013	2.627	3.209	117	110	93	77	80	83	PLA1A	phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661]	Environmental Information Processing;Metabolism	Signal transduction;Lipid metabolism	ko04014//Ras signaling pathway;ko00564//Glycerophospholipid metabolism	K13618;K13618	GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0008970//phospholipase A1 activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0016042//lipid catabolic process;GO:0036150//phosphatidylserine acyl-chain remodeling	--
ENSG00000144840	11.251	12.329	9.8	9.598	9.04	8.37	493	489	331	309	366	327	RABL3	"RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072]"	-	-	-	-	GO:0012505//endomembrane system	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity	GO:0001779//natural killer cell differentiation;GO:0006886//intracellular protein transport;GO:0030183//B cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0046578//regulation of Ras protein signal transduction;GO:0050821//protein stabilization;GO:1903059//regulation of protein lipidation	--
ENSG00000144843	5.749	6.637	7.23	8.639	6.69	8.836	345	392	304	340	359	412	ADPRH	ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269]	-	-	-	-	GO:0005615//extracellular space;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0055037//recycling endosome	"GO:0000287//magnesium ion binding;GO:0003875//ADP-ribosylarginine hydrolase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0030955//potassium ion binding;GO:0046872//metal ion binding"	GO:0006464//cellular protein modification process;GO:0051725//protein de-ADP-ribosylation;GO:0090630//activation of GTPase activity;GO:2000785//regulation of autophagosome assembly	--
ENSG00000144847	0.205	0.151	0.138	0.142	0.125	0.068	5	11	7	7	7	2	IGSF11	immunoglobulin superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:16669]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06791	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0060076//excitatory synapse	GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0040008//regulation of growth;GO:0045185//maintenance of protein location;GO:0048167//regulation of synaptic plasticity;GO:0061885//positive regulation of mini excitatory postsynaptic potential;GO:1900273//positive regulation of long-term synaptic potentiation	--
ENSG00000144848	15.709	17.788	16.337	17.106	15.632	17.255	522	573	410	423	446	406	ATG3	autophagy related 3 [Source:HGNC Symbol;Acc:HGNC:20962]	Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Transport and catabolism;Transport and catabolism	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko04136//Autophagy - other	K08343;K08343;K08343	GO:0000153//cytoplasmic ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019776//Atg8 ligase activity;GO:0019777//Atg12 transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019899//enzyme binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006464//cellular protein modification process;GO:0006612//protein targeting to membrane;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0016567//protein ubiquitination;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0044804//autophagy of nucleus;GO:0050765//negative regulation of phagocytosis;GO:1902017//regulation of cilium assembly	--
ENSG00000144852	0	0	0.024	0	0.021	0	0	0	1	0	1	0	NR1I2	nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016604//nuclear body;GO:0045111//intermediate filament cytoskeleton	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016922//nuclear receptor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006805//xenobiotic metabolic process;GO:0007165//signal transduction;GO:0008202//steroid metabolic process;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0042178//xenobiotic catabolic process;GO:0042908//xenobiotic transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	THR-like
ENSG00000144857	25.807	26.469	24.404	16.706	19.723	18.552	2081.23	2069.16	1287.18	943.36	1358.96	1044.68	BOC	"BOC cell adhesion associated, oncogene regulated [Source:HGNC Symbol;Acc:HGNC:17173]"	Organismal Systems;Environmental Information Processing	Development and regeneration;Signal transduction	ko04360//Axon guidance;ko04340//Hedgehog signaling pathway	K20020;K20020	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0044295//axonal growth cone	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007224//smoothened signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0045663//positive regulation of myoblast differentiation;GO:0098609//cell-cell adhesion	--
ENSG00000144867	35.351	38.282	36.852	34.83	33.549	33.195	1879	1989.06	1452.11	1397.02	1518.1	1323	SRPRB	SRP receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:24085]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K12272	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005785//signal recognition particle receptor complex;GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005525//GTP binding	"GO:0006617//SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition;GO:0045047//protein targeting to ER"	--
ENSG00000144868	6.465	7.043	6.642	9.807	8.024	8.813	354	313	221	265	300	249	TMEM108	transmembrane protein 108 [Source:HGNC Symbol;Acc:HGNC:28451]	-	-	-	-	GO:0005575//cellular_component;GO:0005768//endosome;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0045202//synapse;GO:1904115//axon cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006898//receptor-mediated endocytosis;GO:0008090//retrograde axonal transport;GO:0008150//biological_process;GO:0021542//dentate gyrus development;GO:0031175//neuron projection development;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0097106//postsynaptic density organization;GO:0097484//dendrite extension;GO:0098815//modulation of excitatory postsynaptic potential;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus	--
ENSG00000144891	0.031	0	0	0	0	0.153	1	0	0	0	0	5	AGTR1	angiotensin II receptor type 1 [Source:HGNC Symbol;Acc:HGNC:336]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Infectious disease: viral;Signal transduction;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Circulatory system;Signal transduction;Circulatory system;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04925//Aldosterone synthesis and secretion;ko04924//Renin secretion;ko04927//Cortisol synthesis and secretion;ko04614//Renin-angiotensin system	K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166;K04166	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001596//angiotensin type I receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding;GO:0031711//bradykinin receptor binding;GO:0046982//protein heterodimerization activity	GO:0001558//regulation of cell growth;GO:0001822//kidney development;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0002034//maintenance of blood vessel diameter homeostasis by renin-angiotensin;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007266//Rho protein signal transduction;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010873//positive regulation of cholesterol esterification;GO:0019229//regulation of vasoconstriction;GO:0019722//calcium-mediated signaling;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032430//positive regulation of phospholipase A2 activity;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0034374//low-density lipoprotein particle remodeling;GO:0035813//regulation of renal sodium excretion;GO:0038166//angiotensin-activated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0046718//viral entry into host cell;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050896//response to stimulus;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060326//cell chemotaxis;GO:0086097//phospholipase C-activating angiotensin-activated signaling pathway;GO:0097746//blood vessel diameter maintenance;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000144893	0.246	0.543	0.34	0.174	0.276	0.464	51	76.14	44.01	24	47.79	51	MED12L	mediator complex subunit 12L [Source:HGNC Symbol;Acc:HGNC:16050]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15162	GO:0005634//nucleus;GO:0016592//mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000144895	29.511	33.806	26.018	21.624	25.943	24.742	1000	1083	610	553	711	596	EIF2A	eukaryotic translation initiation factor 2A [Source:HGNC Symbol;Acc:HGNC:3254]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0022627//cytosolic small ribosomal subunit;GO:0072562//blood microparticle	GO:0000049//tRNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0045296//cadherin binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0032933//SREBP signaling pathway;GO:0042255//ribosome assembly;GO:1990928//response to amino acid starvation	--
ENSG00000144908	0.261	0.235	0.8	0.31	0.205	0.06	10	15	10	14	11	2	ALDH1L1	aldehyde dehydrogenase 1 family member L1 [Source:HGNC Symbol;Acc:HGNC:3978]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K00289;K00289	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0016155//formyltetrahydrofolate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016742//hydroxymethyl-, formyl- and related transferase activity"	GO:0006730//one-carbon metabolic process;GO:0006740//NADPH regeneration;GO:0009058//biosynthetic process;GO:0009258//10-formyltetrahydrofolate catabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000144909	5.033	4.496	4.401	3.369	4.232	4.64	480	431	310	238	341	322	OSBPL11	oxysterol binding protein like 11 [Source:HGNC Symbol;Acc:HGNC:16397]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0032934//sterol binding	GO:0006869//lipid transport;GO:0010890//positive regulation of sequestering of triglyceride;GO:0015918//sterol transport;GO:0045444//fat cell differentiation	--
ENSG00000144935	1.878	3.38	1.843	1.539	2.348	1.515	171	176	126	106	130	101	TRPC1	transient receptor potential cation channel subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:12333]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Development and regeneration;Nervous system;Nervous system;Digestive system;Endocrine system	ko04360//Axon guidance;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko04972//Pancreatic secretion;ko04929//GnRH secretion	K04964;K04964;K04964;K04964;K04964	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034703//cation channel complex;GO:0043235//receptor complex	"GO:0005102//signaling receptor binding;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0044325//transmembrane transporter binding;GO:0051117//ATPase binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0042438//melanin biosynthetic process;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:1903779//regulation of cardiac conduction	--
ENSG00000144959	3.737	3.412	3.864	3.715	4.309	4.852	337	318	264	254	339	327	NCEH1	neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Digestive system;Endocrine system;Digestive system	ko04934//Cushing syndrome;ko04976//Bile secretion;ko04927//Cortisol synthesis and secretion;ko04979//Cholesterol metabolism	K14349;K14349;K14349;K14349	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004771//sterol esterase activity;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity;GO:0042301//phosphate ion binding;GO:0052689//carboxylic ester hydrolase activity	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0016042//lipid catabolic process;GO:0034383//low-density lipoprotein particle clearance;GO:0046485//ether lipid metabolic process;GO:0060395//SMAD protein signal transduction	--
ENSG00000144962	0	0	0	0	0	0	0	0	0	0	0	0	SPATA16	spermatogenesis associated 16 [Source:HGNC Symbol;Acc:HGNC:29935]	-	-	-	-	GO:0005794//Golgi apparatus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008150//biological_process;GO:0030154//cell differentiation	--
ENSG00000145002	1.187	1.499	1.06	1.396	1.129	1.791	51.84	63.05	31.77	46.17	41.25	55.53	FAM86B2	family with sequence similarity 86 member B2 [Source:HGNC Symbol;Acc:HGNC:32222]	-	-	-	-	GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0008150//biological_process;GO:0032259//methylation	--
ENSG00000145012	9.368	3.549	5.634	5.437	3.131	4.099	1612.37	1203.17	821.87	610.68	1000.85	709.16	LPP	LIM domain containing preferred translocation partner in lipoma [Source:HGNC Symbol;Acc:HGNC:6679]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0008150//biological_process;GO:0098609//cell-cell adhesion	--
ENSG00000145014	1.585	1.67	1.278	1.871	1.626	1.746	71	77	47	58	60	42	TMEM44	transmembrane protein 44 [Source:HGNC Symbol;Acc:HGNC:25120]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000145016	4.279	5.043	6.176	3.499	4.998	6.782	391	366	311	286	327	355	RUBCN	rubicon autophagy regulator [Source:HGNC Symbol;Acc:HGNC:28991]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K19330	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006909//phagocytosis;GO:0006914//autophagy;GO:0010507//negative regulation of autophagy;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity;GO:0045806//negative regulation of endocytosis;GO:0071985//multivesicular body sorting pathway;GO:1901097//negative regulation of autophagosome maturation	--
ENSG00000145020	7.701	9.396	8.935	11.61	10.771	9.671	315.58	383.97	270.87	349.82	372	284.18	AMT	aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00670//One carbon pool by folate"	K00605;K00605;K00605;K00605;K00605	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004047//aminomethyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity	GO:0006546//glycine catabolic process;GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0032259//methylation	--
ENSG00000145022	19.659	20.429	20.429	22.392	22.353	19.775	787	822	604	664	756	576	TCTA	T cell leukemia translocation altered [Source:HGNC Symbol;Acc:HGNC:11692]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0045671//negative regulation of osteoclast differentiation;GO:0072675//osteoclast fusion	--
ENSG00000145029	11.055	11.658	9.765	14.992	14.416	14.754	406.34	444.01	259.8	425.67	432	382.92	NICN1	nicolin 1 [Source:HGNC Symbol;Acc:HGNC:18317]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005874//microtubule	GO:0005515//protein binding	-	--
ENSG00000145040	0	0	0	0	0	0	0	0	0	0	0	0	UCN2	urocortin 2 [Source:HGNC Symbol;Acc:HGNC:18414]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05257	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0042562//hormone binding;GO:0051429//corticotropin-releasing hormone receptor binding;GO:0051431//corticotropin-releasing hormone receptor 2 binding	GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007586//digestion;GO:0009755//hormone-mediated signaling pathway;GO:0031669//cellular response to nutrient levels	--
ENSG00000145041	7.987	8.056	8.093	7.208	7.626	8.445	941.87	955.04	704.51	627.81	757.47	723.26	DCAF1	DDB1 and CUL4 associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30911]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K11789	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030331//estrogen receptor binding;GO:0106310//protein serine kinase activity;GO:1990244//histone kinase activity (H2A-T120 specific)	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0016310//phosphorylation;GO:0016567//protein ubiquitination;GO:0030183//B cell differentiation;GO:0033151//V(D)J recombination;GO:0035212//cell competition in a multicellular organism;GO:1990245//histone H2A-T120 phosphorylation	--
ENSG00000145050	47.098	47.701	50.205	50.722	44.462	41.424	888	904	699	708	708	568	MANF	mesencephalic astrocyte derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:15461]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0033018//sarcoplasmic reticulum lumen;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008289//lipid binding;GO:0120146//sulfatide binding	GO:0006986//response to unfolded protein;GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0071542//dopaminergic neuron differentiation;GO:1905897//regulation of response to endoplasmic reticulum stress	--
ENSG00000145087	0.01	0.032	0	0.021	0.018	0.065	2	2	0	1	3	3	STXBP5L	syntaxin binding protein 5L [Source:HGNC Symbol;Acc:HGNC:30757]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031201//SNARE complex;GO:0031594//neuromuscular junction;GO:0098992//neuronal dense core vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0045159//myosin II binding	GO:0006887//exocytosis;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0042593//glucose homeostasis;GO:0046676//negative regulation of insulin secretion;GO:0050708//regulation of protein secretion;GO:0050790//regulation of catalytic activity;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000145088	0.531	0.205	0.288	0.136	0.114	0.332	11	4	4	2	2	5	EAF2	ELL associated factor 2 [Source:HGNC Symbol;Acc:HGNC:23115]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0016607//nuclear speck;GO:0032783//super elongation complex	GO:0003711//transcription elongation regulator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0030308//negative regulation of cell growth;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development"	--
ENSG00000145103	0.194	0.149	0.172	0.326	0.3	0.274	11	7	7	11	15	11	ILDR1	immunoglobulin like domain containing receptor 1 [Source:HGNC Symbol;Acc:HGNC:28741]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0061689//tricellular tight junction;GO:0070160//tight junction	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0070506//high-density lipoprotein particle receptor activity	GO:0006897//endocytosis;GO:0010669//epithelial structure maintenance;GO:0043484//regulation of RNA splicing;GO:0061833//protein localization to tricellular tight junction;GO:0070542//response to fatty acid;GO:0090277//positive regulation of peptide hormone secretion;GO:1904274//tricellular tight junction assembly;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000145107	0	0	0	0.082	0.114	0	0	0	0	2	1	0	TM4SF19	transmembrane 4 L six family member 19 [Source:HGNC Symbol;Acc:HGNC:25167]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000145113	0.013	0	0	0	0	0	1	0	0	0	0	0	MUC4	"mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0031982//vesicle;GO:0070062//extracellular exosome	"GO:0005176//ErbB-2 class receptor binding;GO:0030197//extracellular matrix constituent, lubricant activity"	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010469//regulation of signaling receptor activity;GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000145147	5.198	5.287	4.791	3.814	4.86	4.904	744	747	493	423	565	398	SLIT2	slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06839	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005095//GTPase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043237//laminin-1 binding;GO:0043394//proteoglycan binding;GO:0048495//Roundabout binding	GO:0001657//ureteric bud development;GO:0001933//negative regulation of protein phosphorylation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0010593//negative regulation of lamellipodium assembly;GO:0010596//negative regulation of endothelial cell migration;GO:0014912//negative regulation of smooth muscle cell migration;GO:0016043//cellular component organization;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0021972//corticospinal neuron axon guidance through spinal cord;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030837//negative regulation of actin filament polymerization;GO:0031290//retinal ganglion cell axon guidance;GO:0032870//cellular response to hormone stimulus;GO:0035385//Roundabout signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043116//negative regulation of vascular permeability;GO:0048699//generation of neurons;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048846//axon extension involved in axon guidance;GO:0050772//positive regulation of axonogenesis;GO:0050919//negative chemotaxis;GO:0050929//induction of negative chemotaxis;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0051414//response to cortisol;GO:0060412//ventricular septum morphogenesis;GO:0061364//apoptotic process involved in luteolysis;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0071504//cellular response to heparin;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0071676//negative regulation of mononuclear cell migration;GO:0090024//negative regulation of neutrophil chemotaxis;GO:0090027//negative regulation of monocyte chemotaxis;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:0090288//negative regulation of cellular response to growth factor stimulus	--
ENSG00000145191	25.344	24.563	29.159	26.716	26.084	30.551	1252	1219	990	933	1058	1049	EIF2B5	eukaryotic translation initiation factor 2B subunit epsilon [Source:HGNC Symbol;Acc:HGNC:3261]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K03240	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex	GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	GO:0001541//ovarian follicle development;GO:0006412//translation;GO:0006413//translational initiation;GO:0007568//aging;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0010226//response to lithium ion;GO:0014002//astrocyte development;GO:0014003//oligodendrocyte development;GO:0021766//hippocampus development;GO:0034976//response to endoplasmic reticulum stress;GO:0042552//myelination;GO:0043065//positive regulation of apoptotic process;GO:0043434//response to peptide hormone;GO:0045727//positive regulation of translation;GO:0045948//positive regulation of translational initiation;GO:0048708//astrocyte differentiation;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway	--
ENSG00000145192	0	0.061	0	0	0	0	0	2	0	0	0	0	AHSG	alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0031012//extracellular matrix;GO:0031093//platelet alpha granule lumen;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019210//kinase inhibitor activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0006907//pinocytosis;GO:0006953//acute-phase response;GO:0010951//negative regulation of endopeptidase activity;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050727//regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis	--
ENSG00000145194	0.019	0.093	0.021	0	0.022	0	1	5	1	0	1	0	ECE2	endothelin converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13275]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0003824//catalytic activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008152//metabolic process;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0032259//methylation	--
ENSG00000145198	0.194	0.21	0.283	0.264	0.235	0.319	16	18	16	15	17	19	VWA5B2	von Willebrand factor A domain containing 5B2 [Source:HGNC Symbol;Acc:HGNC:25144]	-	-	-	-	-	-	-	--
ENSG00000145214	3.307	3.621	3.917	3.957	3.959	4.205	318	351	279	280	320	295	DGKQ	diacylglycerol kinase theta [Source:HGNC Symbol;Acc:HGNC:2856]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism;Development and regeneration	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism;ko04361//Axon regeneration	K00901;K00901;K00901;K00901;K00901;K00901;K00901	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0043274//phospholipase binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	GO:0006111//regulation of gluconeogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019933//cAMP-mediated signaling;GO:0030168//platelet activation;GO:0033198//response to ATP;GO:0035556//intracellular signal transduction;GO:0044255//cellular lipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051591//response to cAMP;GO:0070493//thrombin-activated receptor signaling pathway;GO:0070528//protein kinase C signaling;GO:0090181//regulation of cholesterol metabolic process;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1903432//regulation of TORC1 signaling;GO:2000064//regulation of cortisol biosynthetic process;GO:2000182//regulation of progesterone biosynthetic process	--
ENSG00000145216	12.269	12.314	10.839	9.566	11.271	10.703	552.02	540.33	333.96	303.21	366.03	340.66	FIP1L1	factor interacting with PAPOLA and CPSF1 [Source:HGNC Symbol;Acc:HGNC:19124]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14405	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000145217	1.174	1.013	1.37	0.877	1.189	1.126	74	67	64	46	72	58	SLC26A1	solute carrier family 26 member 1 [Source:HGNC Symbol;Acc:HGNC:10993]	Human Diseases	Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species	K14700	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000145220	2.11	1.636	2.142	1.348	1.285	1.407	68	53	51	32	35	33	LYAR	Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0042995//cell projection	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0006364//rRNA processing;GO:0045087//innate immune response;GO:0045824//negative regulation of innate immune response;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0048821//erythrocyte development;GO:0050766//positive regulation of phagocytosis	Others
ENSG00000145241	2.156	1.617	1.156	0.954	0.976	1.302	159	116	66	53	60	68	CENPC	centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0030496//midbody"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019237//centromeric DNA binding;GO:0042802//identical protein binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051382//kinetochore assembly;GO:0051455//monopolar spindle attachment to meiosis I kinetochore	--
ENSG00000145242	0.665	0.824	0.775	0.972	0.93	1.219	89	101	73	96	95	103	EPHA5	EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05106	GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019933//cAMP-mediated signaling;GO:0021766//hippocampus development;GO:0032793//positive regulation of CREB transcription factor activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0033674//positive regulation of kinase activity;GO:0043087//regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0048666//neuron development;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000145244	0.051	0.02	0.125	0.052	0.134	0.042	5	2	9	4	11	3	CORIN	"corin, serine peptidase [Source:HGNC Symbol;Acc:HGNC:19012]"	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0003050//regulation of systemic arterial blood pressure by atrial natriuretic peptide;GO:0006508//proteolysis;GO:0007565//female pregnancy;GO:0008217//regulation of blood pressure;GO:0016486//peptide hormone processing;GO:0035813//regulation of renal sodium excretion;GO:1903779//regulation of cardiac conduction	--
ENSG00000145246	8.408	8.868	9.072	8.379	8.835	9.928	1124	1143	878	815	1006	986	ATP10D	ATPase phospholipid transporting 10D (putative) [Source:HGNC Symbol;Acc:HGNC:13549]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140351//glycosylceramide flippase activity	GO:0006812//cation transport;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation	--
ENSG00000145247	16.388	18.675	19.6	15.23	14.505	11.936	292	354	265	219	232	152	OCIAD2	OCIA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28685]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005794//Golgi apparatus	-	GO:0006897//endocytosis;GO:0009617//response to bacterium;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000145248	0.341	0.475	0.216	0.276	0.458	0.188	15	21	7	9	17	6	SLC10A4	solute carrier family 10 member 4 [Source:HGNC Symbol;Acc:HGNC:22980]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008508//bile acid:sodium symporter activity;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport	--
ENSG00000145283	0	0	0	0	0	0	0	0	0	0	0	0	SLC10A6	solute carrier family 10 member 6 [Source:HGNC Symbol;Acc:HGNC:30603]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008508//bile acid:sodium symporter activity;GO:0015293//symporter activity;GO:0043250//sodium-dependent organic anion transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0015721//bile acid and bile salt transport;GO:0043251//sodium-dependent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000145284	8.722	9.353	8.997	7.237	8.128	6.234	550	592	419	338	433	286	SCD5	stearoyl-CoA desaturase 5 [Source:HGNC Symbol;Acc:HGNC:21088]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Signal transduction;Endocrine system;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids	K00507;K00507;K00507;K00507;K00507;K00507	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:1903966//monounsaturated fatty acid biosynthetic process	--
ENSG00000145287	0.855	0.547	0.801	1.425	0.278	0.731	11	10	6	14	6	7	PLAC8	placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254]	-	-	-	-	GO:0005576//extracellular region;GO:0035578//azurophil granule lumen	GO:0003682//chromatin binding	GO:0008284//positive regulation of cell population proliferation;GO:0009409//response to cold;GO:0040015//negative regulation of multicellular organism growth;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050873//brown fat cell differentiation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000145293	28.022	24.67	29.59	26.325	23.308	28.067	1196	1061	926	830	845	874	ENOPH1	enolase-phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:24599]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K09880;K09880	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0043715//2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity;GO:0043716//2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity;GO:0043874//acireductone synthase activity;GO:0046872//metal ion binding"	GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0016311//dephosphorylation;GO:0019284//L-methionine salvage from S-adenosylmethionine;GO:0019509//L-methionine salvage from methylthioadenosine	--
ENSG00000145309	0	0	0	0	0.075	0	0	0	0	0	2	0	CABS1	"calcium binding protein, spermatid associated 1 [Source:HGNC Symbol;Acc:HGNC:30710]"	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005509//calcium ion binding	GO:0007283//spermatogenesis;GO:0030317//flagellated sperm motility	--
ENSG00000145321	0	0	0	0	0	0	0	0	0	0	0	0	GC	GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003779//actin binding;GO:0005499//vitamin D binding;GO:0090482//vitamin transmembrane transporter activity;GO:1902118//calcidiol binding	GO:0035461//vitamin transmembrane transport;GO:0042359//vitamin D metabolic process;GO:0051180//vitamin transport	--
ENSG00000145331	0.964	1.174	0.538	0.614	1.126	0.43	50	60	29	23	36	23	TRMT10A	tRNA methyltransferase 10A [Source:HGNC Symbol;Acc:HGNC:28403]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0016740//transferase activity;GO:0052905//tRNA (guanine(9)-N(1))-methyltransferase activity	GO:0002939//tRNA N1-guanine methylation;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000145332	5.246	4.687	4.443	3.749	3.928	5.334	510	511	329	286	357	372	KLHL8	kelch like family member 8 [Source:HGNC Symbol;Acc:HGNC:18644]	-	-	-	-	GO:0005654//nucleoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000145335	38.67	38.546	43.295	40.999	34.934	36.596	1063	1061	862	840	898	805	SNCA	synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05012//Parkinson disease	K04528;K04528;K04528	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016234//inclusion body;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0031092//platelet alpha granule membrane;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse;GO:0099512//supramolecular fiber	GO:0000149//SNARE binding;GO:0000287//magnesium ion binding;GO:0000976//transcription cis-regulatory region binding;GO:0003779//actin binding;GO:0004860//protein kinase inhibitor activity;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008198//ferrous iron binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0019894//kinesin binding;GO:0030544//Hsp70 protein binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0051219//phosphoprotein binding;GO:0070840//dynein complex binding;GO:1903136//cuprous ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001774//microglial cell activation;GO:0001921//positive regulation of receptor recycling;GO:0001956//positive regulation of neurotransmitter secretion;GO:0001963//synaptic transmission, dopaminergic;GO:0006469//negative regulation of protein kinase activity;GO:0006631//fatty acid metabolic process;GO:0006638//neutral lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007006//mitochondrial membrane organization;GO:0007268//chemical synaptic transmission;GO:0008344//adult locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0010040//response to iron(II) ion;GO:0010517//regulation of phospholipase activity;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0014048//regulation of glutamate secretion;GO:0014059//regulation of dopamine secretion;GO:0016079//synaptic vesicle exocytosis;GO:0016082//synaptic vesicle priming;GO:0022898//regulation of transmembrane transporter activity;GO:0031115//negative regulation of microtubule polymerization;GO:0031623//receptor internalization;GO:0031648//protein destabilization;GO:0032026//response to magnesium ion;GO:0032410//negative regulation of transporter activity;GO:0032496//response to lipopolysaccharide;GO:0032769//negative regulation of monooxygenase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034341//response to interferon-gamma;GO:0034599//cellular response to oxidative stress;GO:0035067//negative regulation of histone acetylation;GO:0035493//SNARE complex assembly;GO:0035543//positive regulation of SNARE complex assembly;GO:0040012//regulation of locomotion;GO:0042416//dopamine biosynthetic process;GO:0042417//dopamine metabolic process;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0043030//regulation of macrophage activation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045807//positive regulation of endocytosis;GO:0045920//negative regulation of exocytosis;GO:0045921//positive regulation of exocytosis;GO:0046928//regulation of neurotransmitter secretion;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048488//synaptic vesicle endocytosis;GO:0048489//synaptic vesicle transport;GO:0050729//positive regulation of inflammatory response;GO:0050806//positive regulation of synaptic transmission;GO:0050808//synapse organization;GO:0050812//regulation of acyl-CoA biosynthetic process;GO:0051259//protein complex oligomerization;GO:0051262//protein tetramerization;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051585//negative regulation of dopamine uptake involved in synaptic transmission;GO:0051612//negative regulation of serotonin uptake;GO:0051621//regulation of norepinephrine uptake;GO:0051622//negative regulation of norepinephrine uptake;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0061024//membrane organization;GO:0070495//negative regulation of thrombin-activated receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0071280//cellular response to copper ion;GO:0071872//cellular response to epinephrine stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097435//supramolecular fiber organization;GO:1901214//regulation of neuron death;GO:1901215//negative regulation of neuron death;GO:1901216//positive regulation of neuron death;GO:1902957//negative regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1903284//positive regulation of glutathione peroxidase activity;GO:1903285//positive regulation of hydrogen peroxide catabolic process;GO:1903421//regulation of synaptic vesicle recycling;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1904715//negative regulation of chaperone-mediated autophagy;GO:1905606//regulation of presynapse assembly;GO:2000377//regulation of reactive oxygen species metabolic process"	--
ENSG00000145337	20.759	20.873	19.718	20.976	19.457	19.459	564.5	570.5	396	422.5	447	385	PYURF	PIGY upstream open reading frame [Source:HGNC Symbol;Acc:HGNC:44317]	-	-	-	-	GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane	-	-	--
ENSG00000145348	7.594	7.791	7.354	8.399	8.588	7.338	598.9	563.41	386	397	476.02	417	TBCK	TBC1 domain containing kinase [Source:HGNC Symbol;Acc:HGNC:28261]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0072686//mitotic spindle	GO:0004672//protein kinase activity;GO:0005096//GTPase activator activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation;GO:0008283//cell population proliferation;GO:0030036//actin cytoskeleton organization;GO:0032006//regulation of TOR signaling;GO:0090630//activation of GTPase activity	--
ENSG00000145349	15.268	13.567	16.427	13.268	16.355	16.033	1046	988	864	738	878	799	CAMK2D	calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Development and regeneration;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Circulatory system;Cell growth and death;Nervous system;Nervous system;Signal transduction;Nervous system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Endocrine system;Endocrine system;Endocrine system;Signal transduction;Cancer: specific types;Digestive system;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04217//Necroptosis;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko05214//Glioma;ko04971//Gastric acid secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030666//endocytic vesicle membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0043226//organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019871//sodium channel inhibitor activity;GO:0031432//titin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0106310//protein serine kinase activity	GO:0001558//regulation of cell growth;GO:0002026//regulation of the force of heart contraction;GO:0003254//regulation of membrane depolarization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0008016//regulation of heart contraction;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010649//regulation of cell communication by electrical coupling;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0046777//protein autophosphorylation;GO:0055119//relaxation of cardiac muscle;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060341//regulation of cellular localization;GO:0071277//cellular response to calcium ion;GO:0086003//cardiac muscle cell contraction;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098901//regulation of cardiac muscle cell action potential;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:1901725//regulation of histone deacetylase activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1901897//regulation of relaxation of cardiac muscle;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000145354	24.186	22.983	27.361	24.553	18.113	26.397	895	823	667	647	593	659	CISD2	CDGSH iron sulfur domain 2 [Source:HGNC Symbol;Acc:HGNC:24212]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097038//perinuclear endoplasmic reticulum	"GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0010259//multicellular organism aging;GO:0010506//regulation of autophagy	--
ENSG00000145358	4.129	3.923	5.59	5.199	3.616	5.903	223	213	223	208	165	232	DDIT4L	DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0009968//negative regulation of signal transduction	--
ENSG00000145362	15.372	14.629	12.896	8.523	10.966	11.024	2334	2197	1405	930	1371	1205	ANK2	ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K10380	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030315//T-tubule;GO:0031430//M band;GO:0031672//A band;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0043034//costamere;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055037//recycling endosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030507//spectrin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0044325//transmembrane transporter binding;GO:0051117//ATPase binding;GO:0140031//phosphorylation-dependent protein binding	GO:0002027//regulation of heart rate;GO:0003283//atrial septum development;GO:0006874//cellular calcium ion homeostasis;GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010628//positive regulation of gene expression;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0015031//protein transport;GO:0030913//paranodal junction assembly;GO:0031647//regulation of protein stability;GO:0033292//T-tubule organization;GO:0033365//protein localization to organelle;GO:0034394//protein localization to cell surface;GO:0034613//cellular protein localization;GO:0036309//protein localization to M-band;GO:0036371//protein localization to T-tubule;GO:0043268//positive regulation of potassium ion transport;GO:0050821//protein stabilization;GO:0051179//localization;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0051597//response to methylmercury;GO:0051924//regulation of calcium ion transport;GO:0051928//positive regulation of calcium ion transport;GO:0055117//regulation of cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0070972//protein localization to endoplasmic reticulum;GO:0072659//protein localization to plasma membrane;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086014//atrial cardiac muscle cell action potential;GO:0086015//SA node cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086066//atrial cardiac muscle cell to AV node cell communication;GO:0086070//SA node cell to atrial cardiac muscle cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098907//regulation of SA node cell action potential;GO:0098910//regulation of atrial cardiac muscle cell action potential;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:1901021//positive regulation of calcium ion transmembrane transporter activity;GO:2001259//positive regulation of cation channel activity	--
ENSG00000145365	9.118	7.454	6.564	6.008	8.3	9.981	313	311	211	215	261	280	TIFA	TRAF interacting protein with forkhead associated domain [Source:HGNC Symbol;Acc:HGNC:19075]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K23826	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002376//immune system process;GO:0002753//cytoplasmic pattern recognition receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0051260//protein homooligomerization	--
ENSG00000145375	1.778	1.806	1.309	1.291	1.227	1.25	242	214	134	117	137	129	SPATA5	spermatogenesis associated 5 [Source:HGNC Symbol;Acc:HGNC:18119]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14575	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0030154//cell differentiation	--
ENSG00000145384	0	0	0	0	0	0	0	0	0	0	0	0	FABP2	fatty acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3556]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko03320//PPAR signaling pathway;ko04975//Fat digestion and absorption	K08751;K08751	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0045179//apical cortex	GO:0005324//long-chain fatty acid transporter activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0036041//long-chain fatty acid binding	GO:0006631//fatty acid metabolic process;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0050892//intestinal absorption;GO:0098856//intestinal lipid absorption	--
ENSG00000145386	2.088	1.937	1.663	1.161	1.038	1.109	119	111	70	49	50	46	CCNA2	cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Cell growth and death;Signal transduction;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04110//Cell cycle;ko04152//AMPK signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko05221//Acute myeloid leukemia	K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627;K06627	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097124//cyclin A2-CDK2 complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0016572//histone phosphorylation;GO:0031100//animal organ regeneration;GO:0032355//response to estradiol;GO:0033762//response to glucagon;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0044320//cellular response to leptin stimulus;GO:0044772//mitotic cell cycle phase transition;GO:0044843//cell cycle G1/S phase transition;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048146//positive regulation of fibroblast proliferation;GO:0051301//cell division;GO:0071314//cellular response to cocaine;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071456//cellular response to hypoxia;GO:0071732//cellular response to nitric oxide;GO:0090102//cochlea development;GO:1990314//cellular response to insulin-like growth factor stimulus"	--
ENSG00000145388	6.537	5.449	4.177	3.993	4.518	5.231	607	589	361	313	400	393	METTL14	"methyltransferase 14, N6-adenosine-methyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:29330]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016422//mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0001510//RNA methylation;GO:0006402//mRNA catabolic process;GO:0007283//spermatogenesis;GO:0019827//stem cell population maintenance;GO:0021861//forebrain radial glial cell differentiation;GO:0030154//cell differentiation;GO:0042063//gliogenesis;GO:0045727//positive regulation of translation;GO:0061157//mRNA destabilization;GO:0080009//mRNA methylation;GO:1901533//negative regulation of hematopoietic progenitor cell differentiation"	--
ENSG00000145390	8.552	5.741	5.349	4.322	6.743	7.031	972	634	441	394	567	574	USP53	ubiquitin specific peptidase 53 [Source:HGNC Symbol;Acc:HGNC:29255]	-	-	-	-	GO:0005575//cellular_component;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding	GO:0001508//action potential;GO:0006915//apoptotic process;GO:0007605//sensory perception of sound;GO:0008150//biological_process;GO:0010996//response to auditory stimulus;GO:0016579//protein deubiquitination;GO:0051402//neuron apoptotic process	--
ENSG00000145391	29.251	25.798	25.577	20.98	22.107	19.732	3745	3340	2441	1930	2348	1848	SETD7	"SET domain containing 7, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:30412]"	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Amino acid metabolism	ko01100//Metabolic pathways;ko04068//FoxO signaling pathway;ko00310//Lysine degradation	K11431;K11431;K11431	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006479//protein methylation;GO:0006974//cellular response to DNA damage stimulus;GO:0018022//peptidyl-lysine methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0051570//regulation of histone H3-K9 methylation;GO:0070828//heterochromatin organization"	--
ENSG00000145414	5.072	4.46	4.575	3.72	5.463	3.556	192	165	126	104	175	99	NAF1	nuclear assembly factor 1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:25126]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0070034//telomerase RNA binding	GO:0000454//snoRNA guided rRNA pseudouridine synthesis;GO:0000493//box H/ACA snoRNP assembly;GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0042254//ribosome biogenesis;GO:0043489//RNA stabilization;GO:0051973//positive regulation of telomerase activity;GO:0090669//telomerase RNA stabilization;GO:1904358//positive regulation of telomere maintenance via telomere lengthening;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1905323//telomerase holoenzyme complex assembly	--
ENSG00000145416	0.916	0.712	0.405	1.193	1.518	0.635	104	77	34	91	89	52	MARCHF1	membrane associated ring-CH-type finger 1 [Source:HGNC Symbol;Acc:HGNC:26077]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042287//MHC protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II;GO:0006955//immune response;GO:0016567//protein ubiquitination	--
ENSG00000145423	4.686	5.599	8.503	1.793	2.001	1.394	194	233	260	55	70	42	SFRP2	secreted frizzled related protein 2 [Source:HGNC Symbol;Acc:HGNC:10777]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K02176	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0001968//fibronectin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0017147//Wnt-protein binding;GO:0048018//receptor ligand activity;GO:0061133//endopeptidase activator activity	"GO:0001569//branching involved in blood vessel morphogenesis;GO:0001756//somitogenesis;GO:0001843//neural tube closure;GO:0002063//chondrocyte development;GO:0003151//outflow tract morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0006915//apoptotic process;GO:0007267//cell-cell signaling;GO:0007584//response to nutrient;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009952//anterior/posterior pattern specification;GO:0010629//negative regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010950//positive regulation of endopeptidase activity;GO:0010975//regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0021915//neural tube development;GO:0030111//regulation of Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030199//collagen fibril organization;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0036342//post-anal tail morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043508//negative regulation of JUN kinase activity;GO:0045600//positive regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046546//development of primary male sexual characteristics;GO:0048546//digestive tract morphogenesis;GO:0048856//anatomical structure development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0051216//cartilage development;GO:0060028//convergent extension involved in axis elongation;GO:0060070//canonical Wnt signaling pathway;GO:0060349//bone morphogenesis;GO:0061056//sclerotome development;GO:0061185//negative regulation of dermatome development;GO:0071425//hematopoietic stem cell proliferation;GO:0071481//cellular response to X-ray;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090175//regulation of establishment of planar polarity;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1904956//regulation of midbrain dopaminergic neuron differentiation;GO:2000035//regulation of stem cell division;GO:2000041//negative regulation of planar cell polarity pathway involved in axis elongation"	--
ENSG00000145425	797.915	818.523	745.303	726.507	631.426	615.811	14323	14763	9850	9656	9586	8042	RPS3A	ribosomal protein S3A [Source:HGNC Symbol;Acc:HGNC:10421]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02984;K02984	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006413//translational initiation;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process	--
ENSG00000145428	0.15	0.106	0	0.668	0.281	0.113	4	3	0	6	5	1	RNF175	ring finger protein 175 [Source:HGNC Symbol;Acc:HGNC:27735]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000145431	36.95	31.612	39.764	33.61	32.772	43.152	2115	2062	1639	1482	1603	1737	PDGFC	platelet derived growth factor C [Source:HGNC Symbol;Acc:HGNC:8801]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05218//Melanoma	K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0070851//growth factor receptor binding	GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007417//central nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0048565//digestive tract development;GO:0048568//embryonic organ development;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0060348//bone development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071230//cellular response to amino acid stimulus;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000145439	9.746	8.985	8.468	8.04	9.311	8.852	654	624	432	387	511	452	CBR4	carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis	K11539;K11539;K11539	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:1990204//oxidoreductase complex	"GO:0003955//NAD(P)H dehydrogenase (quinone) activity;GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0005515//protein binding;GO:0008753//NADPH dehydrogenase (quinone) activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048038//quinone binding;GO:0070402//NADPH binding"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0051289//protein homotetramerization;GO:0051290//protein heterotetramerization	--
ENSG00000145451	0	0	0	0	0	0	0	0	0	0	0	0	GLRA3	glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05195	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016935//glycine-gated chloride channel complex;GO:0030054//cell junction;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0016594//glycine binding;GO:0016934//extracellularly glycine-gated chloride channel activity;GO:0022824//transmitter-gated ion channel activity;GO:0022852//glycine-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0046872//metal ion binding	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043200//response to amino acid;GO:0050877//nervous system process;GO:0051260//protein homooligomerization;GO:0060012//synaptic transmission, glycinergic;GO:0060079//excitatory postsynaptic potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000145476	24.97	23.946	26.338	25.241	28.342	26.564	2412	2325	1879	1806	2313	1867	CYP4V2	cytochrome P450 family 4 subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:23198]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0102033//long-chain fatty acid omega-hydroxylase activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0007601//visual perception;GO:0010430//fatty acid omega-oxidation;GO:0016125//sterol metabolic process;GO:0050896//response to stimulus	--
ENSG00000145491	0.554	0.769	0.308	0.227	0.484	0.114	13	17	5	4	9	2	ROPN1L	rhophilin associated tail protein 1 like [Source:HGNC Symbol;Acc:HGNC:24060]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001932//regulation of protein phosphorylation;GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation	--
ENSG00000145494	60.311	55.743	62.253	69.61	56.955	65.877	648	602	494	554	517	515	NDUFS6	NADH:ubiquinone oxidoreductase subunit S6 [Source:HGNC Symbol;Acc:HGNC:7713]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939;K03939	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000145495	33.032	31.559	36.533	32.03	35.422	38.002	3652	3412	2778	2536	3074	3042	MARCHF6	membrane associated ring-CH-type finger 6 [Source:HGNC Symbol;Acc:HGNC:30550]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10661	GO:0000835//ER ubiquitin ligase complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:1990381//ubiquitin-specific protease binding	GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036503//ERAD pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:1904380//endoplasmic reticulum mannose trimming	--
ENSG00000145506	0.398	0.308	0.179	0.274	0.706	0.577	18	14	6	9	27	19	NKD2	NKD inhibitor of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:17046]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04390//Hippo signaling pathway	K03213;K03213	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0070382//exocytic vesicle;GO:0071944//cell periphery	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0032036//myosin heavy chain binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding	GO:0006887//exocytosis;GO:0010954//positive regulation of protein processing;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048210//Golgi vesicle fusion to target membrane;GO:0072659//protein localization to plasma membrane;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000145526	0.073	0.097	0.044	0.112	0.04	0.071	7	3	1	4	3	3	CDH18	cadherin 18 [Source:HGNC Symbol;Acc:HGNC:1757]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000145536	6.37	6.9	5.29	5.048	5.32	3.812	631	690	378	378	449	272	ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif 16 [Source:HGNC Symbol;Acc:HGNC:17108]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001658//branching involved in ureteric bud morphogenesis;GO:0003073//regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0048232//male gamete generation;GO:1902017//regulation of cilium assembly	--
ENSG00000145545	2.861	2.089	1.662	1.907	1.83	2.655	238	196	139	154	172	147	SRD5A1	steroid 5 alpha-reductase 1 [Source:HGNC Symbol;Acc:HGNC:11284]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K12343;K12343	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070852//cell body fiber	"GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0033218//amide binding;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0050213//progesterone 5-alpha-reductase activity;GO:0070402//NADPH binding"	"GO:0001655//urogenital system development;GO:0001889//liver development;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0006710//androgen catabolic process;GO:0007530//sex determination;GO:0007548//sex differentiation;GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0008584//male gonad development;GO:0009267//cellular response to starvation;GO:0009410//response to xenobiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0014850//response to muscle activity;GO:0016101//diterpenoid metabolic process;GO:0021510//spinal cord development;GO:0021766//hippocampus development;GO:0021794//thalamus development;GO:0021854//hypothalamus development;GO:0021983//pituitary gland development;GO:0021987//cerebral cortex development;GO:0022900//electron transport chain;GO:0030154//cell differentiation;GO:0030539//male genitalia development;GO:0030540//female genitalia development;GO:0032354//response to follicle-stimulating hormone;GO:0032355//response to estradiol;GO:0032869//cellular response to insulin stimulus;GO:0033574//response to testosterone;GO:0042428//serotonin metabolic process;GO:0042448//progesterone metabolic process;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0043627//response to estrogen;GO:0060348//bone development;GO:0060416//response to growth hormone;GO:0060992//response to fungicide;GO:0071320//cellular response to cAMP;GO:0071363//cellular response to growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071394//cellular response to testosterone stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071549//cellular response to dexamethasone stimulus;GO:0071872//cellular response to epinephrine stimulus"	--
ENSG00000145555	57.731	57.397	58.467	35.761	43.402	47.56	7487	7394	5462	3469	4735	4484	MYO10	myosin X [Source:HGNC Symbol;Acc:HGNC:7593]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04666//Fc gamma R-mediated phagocytosis	K12559;K12559	GO:0001726//ruffle;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016459//myosin complex;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031527//filopodium membrane;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body	"GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0030507//spectrin binding;GO:0051015//actin filament binding;GO:0060002//plus-end directed microfilament motor activity"	GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0022409//positive regulation of cell-cell adhesion;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051489//regulation of filopodium assembly	--
ENSG00000145569	0.363	0.232	0.139	0.148	0.235	0.235	53	34	15	16	29	25	OTULINL	OTU deubiquitinase with linear linkage specificity like [Source:HGNC Symbol;Acc:HGNC:25629]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane	GO:0005515//protein binding	-	--
ENSG00000145592	127.159	136.511	131.434	136.397	114.717	115.573	3230	3163	2435	2602	2393	2091	RPL37	ribosomal protein L37 [Source:HGNC Symbol;Acc:HGNC:10347]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02922;K02922	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding;GO:0046872//metal ion binding;GO:0097371//MDM2/MDM4 family protein binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000145604	7.629	6.775	10.123	7.833	9.118	8.246	477.1	431.02	402.03	331	391.02	350.04	SKP2	S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases	"Cancer: overview;Infectious disease: viral;Cancer: overview;Signal transduction;Folding, sorting and degradation;Signal transduction;Cell growth and death;Cancer: specific types"	ko05200//Pathways in cancer;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko04150//mTOR signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko05222//Small cell lung cancer	K03875;K03875;K03875;K03875;K03875;K03875;K03875;K03875	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0042802//identical protein binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016310//phosphorylation;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0070936//protein K48-linked ubiquitination;GO:1902916//positive regulation of protein polyubiquitination	--
ENSG00000145623	8.312	10.63	8.652	6.94	7.675	9.386	820	929	611	482	605	595	OSMR	oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signaling molecules and interaction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05057;K05057;K05057	GO:0005886//plasma membrane;GO:0005900//oncostatin-M receptor complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0019955//cytokine binding	GO:0002675//positive regulation of acute inflammatory response;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0034097//response to cytokine;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway	--
ENSG00000145626	0	0	0	0	0	0	0	0	0	0	0	0	UGT3A1	UDP glycosyltransferase family 3 member A1 [Source:HGNC Symbol;Acc:HGNC:26625]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043541//UDP-N-acetylglucosamine transferase complex	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	-	--
ENSG00000145632	26.13	24.447	16.354	19.203	20.36	17.671	1510	1420	698	822	994	743	PLK2	polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699]	Environmental Information Processing	Signal transduction	ko04068//FoxO signaling pathway	K08861	GO:0000785//chromatin;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030425//dendrite;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043008//ATP-dependent protein binding;GO:0106310//protein serine kinase activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006468//protein phosphorylation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007052//mitotic spindle organization;GO:0007265//Ras protein signal transduction;GO:0007613//memory;GO:0010508//positive regulation of autophagy;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0032465//regulation of cytokinesis;GO:0032486//Rap protein signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045732//positive regulation of protein catabolic process;GO:0046599//regulation of centriole replication;GO:0048167//regulation of synaptic plasticity;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0071866//negative regulation of apoptotic process in bone marrow cell;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:2000773//negative regulation of cellular senescence"	--
ENSG00000145642	0	0	0	0	0	0.078	0	0	0	0	0	1	SHISAL2B	shisa like 2B [Source:HGNC Symbol;Acc:HGNC:34236]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000145649	0	0	0	0	0.127	0	0	0	0	0	2	0	GZMA	granzyme A [Source:HGNC Symbol;Acc:HGNC:4708]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K01352	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005634//nucleus	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0009617//response to bacterium;GO:0019835//cytolysis;GO:0032078//negative regulation of endodeoxyribonuclease activity;GO:0043065//positive regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0051354//negative regulation of oxidoreductase activity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0070269//pyroptosis;GO:0140507//granzyme-mediated programmed cell death signaling pathway;GO:1902483//cytotoxic T cell pyroptotic process	--
ENSG00000145675	8.868	5.68	5.257	8.375	9.508	11.424	789	664	472	454	642	495	PIK3R1	phosphoinositide-3-kinase regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8979]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:1990578//perinuclear endoplasmic reticulum membrane"	GO:0001784//phosphotyrosine residue binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0043125//ErbB-3 class receptor binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043559//insulin binding;GO:0043560//insulin receptor substrate binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0046982//protein heterodimerization activity	GO:0001678//cellular glucose homeostasis;GO:0001953//negative regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0006606//protein import into nucleus;GO:0006955//immune response;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010592//positive regulation of lamellipodium assembly;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0015031//protein transport;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030335//positive regulation of cell migration;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032869//cellular response to insulin stimulus;GO:0033120//positive regulation of RNA splicing;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034644//cellular response to UV;GO:0034976//response to endoplasmic reticulum stress;GO:0042307//positive regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045671//negative regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0050821//protein stabilization;GO:0051491//positive regulation of filopodium assembly;GO:0051492//regulation of stress fiber assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0060396//growth hormone receptor signaling pathway;GO:0120183//positive regulation of focal adhesion disassembly;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1903076//regulation of protein localization to plasma membrane;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000145681	0.05	0.03	0	0	0	0	5	3	0	0	0	0	HAPLN1	hyaluronan and proteoglycan link protein 1 [Source:HGNC Symbol;Acc:HGNC:2380]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix	GO:0005540//hyaluronic acid binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007417//central nervous system development	--
ENSG00000145685	23.82	23.033	24.682	24.346	21.266	25.052	2459	2390	1877	1845	1838	1876	LHFPL2	LHFPL tetraspan subfamily member 2 [Source:HGNC Symbol;Acc:HGNC:6588]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007338//single fertilization;GO:0008150//biological_process;GO:0046545//development of primary female sexual characteristics;GO:0046546//development of primary male sexual characteristics;GO:1905516//positive regulation of fertilization	--
ENSG00000145687	32.836	28.461	34.009	30.11	27.059	35.594	1190	1084	978	730	825	873	SSBP2	single stranded DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15831]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000145692	0	0	0	0	0.023	0.027	0	0	0	0	1	1	BHMT	betaine--homocysteine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:1047]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism"	K00544;K00544;K00544	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0008168//methyltransferase activity;GO:0008172//S-methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0047150//betaine-homocysteine S-methyltransferase activity	GO:0006479//protein methylation;GO:0006577//amino-acid betaine metabolic process;GO:0006579//amino-acid betaine catabolic process;GO:0009086//methionine biosynthetic process;GO:0032259//methylation;GO:0050666//regulation of homocysteine metabolic process;GO:0071267//L-methionine salvage	--
ENSG00000145700	0.048	0	0.022	0	0.057	0.012	6	0	2	0	6	1	ANKRD31	ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0010780//meiotic DNA double-strand break formation involved in reciprocal meiotic recombination;GO:0051321//meiotic cell cycle;GO:1903343//positive regulation of meiotic DNA double-strand break formation	--
ENSG00000145703	8.738	5.35	4.345	2.622	2.889	3.519	918	639	382	234	294	269	IQGAP2	IQ motif containing GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:6111]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05767	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030667//secretory granule membrane;GO:0070062//extracellular exosome;GO:0120025//plasma membrane bounded cell projection	"GO:0003779//actin binding;GO:0005095//GTPase inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding;GO:0071933//Arp2/3 complex binding"	GO:0007165//signal transduction;GO:0032956//regulation of actin cytoskeleton organization;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0043086//negative regulation of catalytic activity;GO:0043087//regulation of GTPase activity;GO:0070493//thrombin-activated receptor signaling pathway;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000145708	0	0.029	0	0.04	0	0	0	1	0	1	0	0	CRHBP	corticotropin releasing hormone binding protein [Source:HGNC Symbol;Acc:HGNC:2356]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005767//secondary lysosome;GO:0005771//multivesicular body;GO:0005874//microtubule;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0031045//dense core granule;GO:0043196//varicosity;GO:0043204//perikaryon;GO:0043679//axon terminus	GO:0005515//protein binding;GO:0042277//peptide binding;GO:0051424//corticotropin-releasing hormone binding	"GO:0001963//synaptic transmission, dopaminergic;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0007611//learning or memory;GO:0009755//hormone-mediated signaling pathway;GO:0035865//cellular response to potassium ion;GO:0045055//regulated exocytosis;GO:0048149//behavioral response to ethanol;GO:0051459//regulation of corticotropin secretion;GO:0051460//negative regulation of corticotropin secretion;GO:0071277//cellular response to calcium ion;GO:0071314//cellular response to cocaine;GO:0071320//cellular response to cAMP;GO:0071356//cellular response to tumor necrosis factor;GO:0071391//cellular response to estrogen stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0080135//regulation of cellular response to stress;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:1900011//negative regulation of corticotropin-releasing hormone receptor activity;GO:2000310//regulation of NMDA receptor activity"	--
ENSG00000145715	14.726	10.703	11.528	10.358	10.512	13.214	1154	869	720	626	695	748	RASA1	RAS p21 protein activator 1 [Source:HGNC Symbol;Acc:HGNC:9871]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Development and regeneration	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04360//Axon guidance	K04352;K04352;K04352	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0001784//phosphotyrosine residue binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019870//potassium channel inhibitor activity;GO:0051020//GTPase binding	GO:0000165//MAPK cascade;GO:0000281//mitotic cytokinesis;GO:0001570//vasculogenesis;GO:0001953//negative regulation of cell-matrix adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0030833//regulation of actin filament polymerization;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048013//ephrin receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0051252//regulation of RNA metabolic process	--
ENSG00000145721	0.295	0.446	0.555	0.484	0.288	0.334	23	35	32	28	19	19	LIX1	limb and CNS expressed 1 [Source:HGNC Symbol;Acc:HGNC:18581]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0097352//autophagosome maturation	--
ENSG00000145723	2.503	2.026	1.637	0.954	1.135	1.388	138	126	89	52	69	74	GIN1	gypsy retrotransposon integrase 1 [Source:HGNC Symbol;Acc:HGNC:25959]	-	-	-	-	-	GO:0003676//nucleic acid binding	GO:0015074//DNA integration	--
ENSG00000145725	14.247	8.491	9.158	5.944	5.637	9.826	785	591	394	372	384	369	PPIP5K2	diphosphoinositol pentakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:29035]	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K13024	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0000829//inositol heptakisphosphate kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0033857//diphosphoinositol-pentakisphosphate kinase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0102092//5-diphosphoinositol pentakisphosphate 3-kinase activity"	GO:0006020//inositol metabolic process;GO:0007605//sensory perception of sound;GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process	--
ENSG00000145730	104.699	107.941	93.639	78.549	87.122	77.546	7542	7767	4647	4089	5142	3834	PAM	peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004497//monooxygenase activity;GO:0004504//peptidylglycine monooxygenase activity;GO:0004598//peptidylamidoglycolate lyase activity;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0016829//lyase activity;GO:0019901//protein kinase binding;GO:0031418//L-ascorbic acid binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0001519//peptide amidation;GO:0001666//response to hypoxia;GO:0001676//long-chain fatty acid metabolic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006518//peptide metabolic process;GO:0006629//lipid metabolic process;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0007595//lactation;GO:0008152//metabolic process;GO:0009268//response to pH;GO:0009404//toxin metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010043//response to zinc ion;GO:0018032//protein amidation;GO:0019538//protein metabolic process;GO:0022602//ovulation cycle process;GO:0032355//response to estradiol;GO:0032956//regulation of actin cytoskeleton organization;GO:0042476//odontogenesis;GO:0046688//response to copper ion;GO:0050708//regulation of protein secretion;GO:0051384//response to glucocorticoid;GO:0060135//maternal process involved in female pregnancy;GO:0060173//limb development;GO:0062112//fatty acid primary amide biosynthetic process	--
ENSG00000145734	1.688	1.093	1.145	0.607	0.91	1.065	342	211	161	103	159	144	BDP1	"B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB [Source:HGNC Symbol;Acc:HGNC:13652]"	-	-	-	-	GO:0000126//transcription factor TFIIIB complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0001156//TFIIIC-class transcription factor complex binding;GO:0005515//protein binding	GO:0070898//RNA polymerase III preinitiation complex assembly	--
ENSG00000145736	2.553	3.952	3.793	3.07	2.617	3.888	131.86	145.98	120.26	111.23	110.76	114.38	GTF2H2	general transcription factor IIH subunit 2 [Source:HGNC Symbol;Acc:HGNC:4656]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Transcription;Replication and repair	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K03142;K03142;K03142	GO:0000438//core TFIIH complex portion of holo TFIIH complex;GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding	"GO:0002031//G protein-coupled receptor internalization;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:1905776//positive regulation of DNA helicase activity"	--
ENSG00000145740	24.969	23.61	23.598	25.195	18.628	25.403	1553	1603	1124	1031	1019	1071	SLC30A5	solute carrier family 30 member 5 [Source:HGNC Symbol;Acc:HGNC:19089]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0030667//secretory granule membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0008270//zinc ion binding;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006824//cobalt ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0010043//response to zinc ion;GO:0010155//regulation of proton transport;GO:0030070//insulin processing;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000145741	248.934	255.778	240.04	243.093	230.089	212.186	4685	4849	3341	3396	3671	2913	BTF3	basic transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:1125]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005854//nascent polypeptide-associated complex;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0015031//protein transport;GO:1905551//negative regulation of protein localization to endoplasmic reticulum	--
ENSG00000145743	2.207	1.778	2.11	2.104	1.936	1.938	238	192	168	168	175	152	FBXL17	F-box and leucine rich repeat protein 17 [Source:HGNC Symbol;Acc:HGNC:13615]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0007399//nervous system development;GO:0008589//regulation of smoothened signaling pathway;GO:0014033//neural crest cell differentiation;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051726//regulation of cell cycle	--
ENSG00000145757	0.067	0.183	0.125	0.12	0.198	0.353	3	5	2	4	5	6	SPATA9	spermatogenesis associated 9 [Source:HGNC Symbol;Acc:HGNC:22988]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030154//cell differentiation	--
ENSG00000145777	2.25	2.865	0.346	0.837	0.994	0.962	113	144	13	31	42	35	TSLP	thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05436;K05436	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005139//interleukin-7 receptor binding	GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0032722//positive regulation of chemokine production;GO:0032733//positive regulation of interleukin-10 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032754//positive regulation of interleukin-5 production;GO:0032755//positive regulation of interleukin-6 production;GO:0033005//positive regulation of mast cell activation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0050832//defense response to fungus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071654//positive regulation of chemokine (C-C motif) ligand 1 production;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:1904894//positive regulation of receptor signaling pathway via STAT	--
ENSG00000145779	18.137	18.32	16.868	16.737	21.208	19.216	653	624	461	438	576	494	TNFAIP8	TNF alpha induced protein 8 [Source:HGNC Symbol;Acc:HGNC:17260]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000145780	3.91	3.637	3.873	3.29	3.626	3.675	462	432	338	288	362	316	FEM1C	fem-1 homolog C [Source:HGNC Symbol;Acc:HGNC:16933]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000145781	16.526	13.317	12.436	14.294	11.11	14.796	480	392	273	301	279	315	COMMD10	COMM domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30201]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000145782	11.848	9.23	9.3	7.807	7.362	8.483	603	477	374	325	342	374	ATG12	autophagy related 12 [Source:HGNC Symbol;Acc:HGNC:588]	Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Immune system;Transport and catabolism;Signal transduction;Immune system;Transport and catabolism	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04136//Autophagy - other	K08336;K08336;K08336;K08336;K08336;K08336	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0032991//protein-containing complex;GO:0034045//phagophore assembly site membrane;GO:0034274//Atg12-Atg5-Atg16 complex;GO:0043231//intracellular membrane-bounded organelle;GO:1990234//transferase complex	GO:0005515//protein binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006501//C-terminal protein lipidation;GO:0006914//autophagy;GO:0016236//macroautophagy;GO:0032480//negative regulation of type I interferon production;GO:0044804//autophagy of nucleus;GO:0045824//negative regulation of innate immune response;GO:0050687//negative regulation of defense response to virus;GO:1901096//regulation of autophagosome maturation;GO:1904973//positive regulation of viral translation	--
ENSG00000145794	0.235	0.296	0.266	0.129	0.128	0.218	37	43	31	15	17	25	MEGF10	multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]	-	-	-	-	GO:0001891//phagocytic cup;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0001849//complement component C1q complex binding;GO:0005044//scavenger receptor activity;GO:0005112//Notch binding;GO:0005515//protein binding	GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0014719//skeletal muscle satellite cell activation;GO:0014816//skeletal muscle satellite cell differentiation;GO:0014841//skeletal muscle satellite cell proliferation;GO:0022409//positive regulation of cell-cell adhesion;GO:0033002//muscle cell proliferation;GO:0034109//homotypic cell-cell adhesion;GO:0043277//apoptotic cell clearance;GO:0043652//engulfment of apoptotic cell;GO:0043654//recognition of apoptotic cell;GO:0048627//myoblast development;GO:0048641//regulation of skeletal muscle tissue development;GO:0051147//regulation of muscle cell differentiation;GO:0051451//myoblast migration;GO:0055001//muscle cell development;GO:1902742//apoptotic process involved in development;GO:2000288//positive regulation of myoblast proliferation	--
ENSG00000145808	1.622	1.457	1.883	1.563	1.977	1.745	175	158	150	102	144	137	ADAMTS19	ADAM metallopeptidase with thrombospondin type 1 motif 19 [Source:HGNC Symbol;Acc:HGNC:17111]	-	-	-	-	GO:0005576//extracellular region	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization	--
ENSG00000145817	21.095	23.067	18.2	17.592	18.344	19.504	1301	1282	817	796	884	878	YIPF5	Yip1 domain family member 5 [Source:HGNC Symbol;Acc:HGNC:24877]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030070//insulin processing;GO:0048280//vesicle fusion with Golgi apparatus;GO:0060628//regulation of ER to Golgi vesicle-mediated transport	--
ENSG00000145819	0.912	1.063	0.622	0.885	0.724	0.941	129	140	67	52	58	62	ARHGAP26	Rho GTPase activating protein 26 [Source:HGNC Symbol;Acc:HGNC:17073]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000145824	63.837	61.538	117.729	75.615	71.757	73.871	2254	2186	3070	1985	2143	1905	CXCL14	C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K10033;K10033;K10033	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0045662//negative regulation of myoblast differentiation;GO:0048839//inner ear development;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:2000503//positive regulation of natural killer cell chemotaxis	--
ENSG00000145826	0	0	0	0	0	0	0	0	0	0	0	0	LECT2	leukocyte cell derived chemotaxin 2 [Source:HGNC Symbol;Acc:HGNC:6550]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0006935//chemotaxis	--
ENSG00000145832	0.218	0.284	0.389	0.069	0.106	0.111	17	11	20	4	7	3	SLC25A48	solute carrier family 25 member 48 [Source:HGNC Symbol;Acc:HGNC:30451]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015227//acyl carnitine transmembrane transporter activity	GO:0006844//acyl carnitine transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:1902616//acyl carnitine transmembrane transport	--
ENSG00000145833	9.376	9.392	8.304	6.852	7.339	7.413	792	776	489	378	503	434	DDX46	DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:18681]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12811	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000145839	0	0	0	0	0	0	0	0	0	0	0	0	IL9	interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signal transduction;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko05310//Asthma	K05432;K05432;K05432	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005140//interleukin-9 receptor binding;GO:0008083//growth factor activity	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0016064//immunoglobulin mediated immune response;GO:0030183//B cell differentiation;GO:0030307//positive regulation of cell growth;GO:0032754//positive regulation of interleukin-5 production;GO:0042100//B cell proliferation;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	--
ENSG00000145850	0	0	0	0	0	0	0	0	0	0	0	0	TIMD4	T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000145860	26.967	25.585	24.999	22.294	20.888	24.461	1864	1769	1305	1155	1226	1245	RNF145	ring finger protein 145 [Source:HGNC Symbol;Acc:HGNC:20853]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000145861	0.04	0	0.027	0.027	0	0	2	0	1	1	0	0	C1QTNF2	C1q and TNF related 2 [Source:HGNC Symbol;Acc:HGNC:14325]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer	GO:0005515//protein binding	GO:0019216//regulation of lipid metabolic process	--
ENSG00000145863	0	0	0	0	0	0	0	0	0	0	0	0	GABRA6	gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0099192//cerebellar Golgi cell to granule cell synapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000145864	0.398	0.182	0.532	0.534	0.441	0.801	60	23	28	38	47	61	GABRB2	gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko04726//Serotonergic synapse;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05181;K05181;K05181;K05181;K05181;K05181	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902710//GABA receptor complex;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0016917//GABA receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007605//sensory perception of sound;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0048666//neuron development;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060119//inner ear receptor cell development;GO:0060384//innervation;GO:0071420//cellular response to histamine;GO:0090102//cochlea development;GO:1901215//negative regulation of neuron death;GO:1902476//chloride transmembrane transport;GO:1904862//inhibitory synapse assembly"	--
ENSG00000145868	8.543	7.454	7.793	6.071	6.425	7.43	747	652	509	388	470	469	FBXO38	F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002842//positive regulation of T cell mediated immune response to tumor cell;GO:0010976//positive regulation of neuron projection development;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000145879	0	0	0	0	0	0	0	0	0	0	0	0	SPINK7	serine peptidase inhibitor Kazal type 7 [Source:HGNC Symbol;Acc:HGNC:24643]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000145882	6.27	5.738	6.833	5.177	5.668	4.902	317	303	267	200	255	188	PCYOX1L	prenylcysteine oxidase 1 like [Source:HGNC Symbol;Acc:HGNC:28477]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0110165//cellular anatomical entity	"GO:0001735//prenylcysteine oxidase activity;GO:0016491//oxidoreductase activity;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor"	GO:0030327//prenylated protein catabolic process;GO:0030328//prenylcysteine catabolic process	--
ENSG00000145888	0	0	0	0	0	0	0	0	0	0	0	0	GLRA1	glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05193	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse;GO:0098690//glycinergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016594//glycine binding;GO:0016934//extracellularly glycine-gated chloride channel activity;GO:0022824//transmitter-gated ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0030977//taurine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001508//action potential;GO:0001964//startle response;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007340//acrosome reaction;GO:0007601//visual perception;GO:0007628//adult walking behavior;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043200//response to amino acid;GO:0043576//regulation of respiratory gaseous exchange;GO:0050877//nervous system process;GO:0050884//neuromuscular process controlling posture;GO:0050905//neuromuscular process;GO:0051970//negative regulation of transmission of nerve impulse;GO:0060012//synaptic transmission, glycinergic;GO:0060013//righting reflex;GO:0060079//excitatory postsynaptic potential;GO:0060080//inhibitory postsynaptic potential;GO:0071230//cellular response to amino acid stimulus;GO:0071294//cellular response to zinc ion;GO:0071361//cellular response to ethanol;GO:0097305//response to alcohol;GO:1902476//chloride transmembrane transport;GO:2000344//positive regulation of acrosome reaction"	--
ENSG00000145901	42.192	44.687	40.376	39.294	42.361	31.896	2131	2341	1477	1485	1839	1215	TNIP1	TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K23829	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051019//mitogen-activated protein kinase binding	GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006412//translation;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007159//leukocyte cell-cell adhesion;GO:0009101//glycoprotein biosynthetic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:1903003//positive regulation of protein deubiquitination	--
ENSG00000145907	75.488	67.255	76.191	56.828	59.093	72.609	2662	2605	2023	1582	1853	1855	G3BP1	G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043204//perikaryon;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003729//mRNA binding;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0033677//DNA/RNA helicase activity	GO:0002376//immune system process;GO:0007265//Ras protein signal transduction;GO:0032481//positive regulation of type I interferon production;GO:0032508//DNA duplex unwinding;GO:0034063//stress granule assembly;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0062029//positive regulation of stress granule assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000145908	4.218	2.874	2.26	2.117	2.069	3.286	327	226	132	117	135	175	ZNF300	zinc finger protein 300 [Source:HGNC Symbol;Acc:HGNC:13091]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000145911	0.234	0.337	0.251	0.435	0.229	0.41	29	42	23	40	24	37	N4BP3	NEDD4 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:29852]	-	-	-	-	GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007399//nervous system development	--
ENSG00000145912	44.736	50.771	53.221	56.004	51.614	43.276	552.6	657.05	490.64	546.35	555.48	401.69	NHP2	NHP2 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14377]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11129	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0015030//Cajal body;GO:0031429//box H/ACA snoRNP complex;GO:0072589//box H/ACA scaRNP complex;GO:0090661//box H/ACA telomerase RNP complex;GO:1990904//ribonucleoprotein complex"	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0034511//U3 snoRNA binding;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding	GO:0000454//snoRNA guided rRNA pseudouridine synthesis;GO:0000469//cleavage involved in rRNA processing;GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing;GO:0007004//telomere maintenance via telomerase;GO:0031118//rRNA pseudouridine synthesis;GO:0031120//snRNA pseudouridine synthesis;GO:0042254//ribosome biogenesis;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000145916	14.372	16.328	17.587	17.944	15.945	18.688	667.4	808.95	593.36	558.65	657.52	607.31	RMND5B	required for meiotic nuclear division 5 homolog B [Source:HGNC Symbol;Acc:HGNC:26181]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034657//GID complex;GO:0110165//cellular anatomical entity	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000145919	23.2	24.779	23.74	24.164	21.485	22.947	762	839	552	593	619	532	BOD1	biorientation of chromosomes in cell division 1 [Source:HGNC Symbol;Acc:HGNC:25114]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0048188//Set1C/COMPASS complex"	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding	"GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0051301//cell division;GO:0051568//histone H3-K4 methylation;GO:0071459//protein localization to chromosome, centromeric region;GO:0071962//mitotic sister chromatid cohesion, centromeric;GO:1990758//mitotic sister chromatid biorientation"	--
ENSG00000145920	0	0.01	0	0	0	0	0	1	0	0	0	0	CPLX2	complexin 2 [Source:HGNC Symbol;Acc:HGNC:2310]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15294	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031201//SNARE complex;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex;GO:0070554//synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0048306//calcium-dependent protein binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007399//nervous system development;GO:0016079//synaptic vesicle exocytosis;GO:0017157//regulation of exocytosis;GO:0030154//cell differentiation;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0031915//positive regulation of synaptic plasticity;GO:0043303//mast cell degranulation;GO:0046928//regulation of neurotransmitter secretion	--
ENSG00000145934	1.335	1.76	1.462	1.481	1.55	0.964	275	364	223	221	265	140	TENM2	teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016605//PML body;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0048666//neuron development;GO:0051491//positive regulation of filopodium assembly;GO:0098609//cell-cell adhesion	--
ENSG00000145936	0	0.02	0.014	0	0	0	0	2	1	0	0	0	KCNMB1	potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K04937;K04937;K04937	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0015459//potassium channel regulator activity	GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0007568//aging;GO:0042311//vasodilation;GO:0051592//response to calcium ion;GO:0071361//cellular response to ethanol;GO:0071456//cellular response to hypoxia;GO:0071805//potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903413//cellular response to bile acid	--
ENSG00000145945	2.177	3.164	1.847	2.49	3.523	3.025	76	111	48	64	103	75	FAM50B	family with sequence similarity 50 member B [Source:HGNC Symbol;Acc:HGNC:18789]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030496//midbody;GO:0045171//intercellular bridge	GO:0005515//protein binding	GO:0006325//chromatin organization	--
ENSG00000145949	0.26	0.121	0.27	0.238	0.185	0.357	31	14	23	21	18	31	MYLK4	myosin light chain kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:27972]	Environmental Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Cellular community - eukaryotes;Signal transduction;Endocrine system;Signal transduction;Circulatory system;Immune system;Digestive system	ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04971//Gastric acid secretion	K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907;K00907	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004687//myosin light chain kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000145975	0	0	0	0	0	0	0	0	0	0	0	0	FAM217A	family with sequence similarity 217 member A [Source:HGNC Symbol;Acc:HGNC:21362]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000145979	5.97	7.662	6.729	6.096	5.369	5.701	132	168	110	98	104	91	TBC1D7	TBC1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:21066]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20396	GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0033596//TSC1-TSC2 complex;GO:0036064//ciliary basal body	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0031398//positive regulation of protein ubiquitination;GO:0032007//negative regulation of TOR signaling;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0070848//response to growth factor;GO:0090630//activation of GTPase activity;GO:1902018//negative regulation of cilium assembly	--
ENSG00000145982	8.106	8.024	7.657	9.566	9.432	8.488	275	270	194	244	266	200	FARS2	"phenylalanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21062]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01889	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004826//phenylalanine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0008033//tRNA processing;GO:0043039//tRNA aminoacylation	--
ENSG00000145990	1.071	0.82	0.812	0.879	1.052	1.29	169	126	88	114	152	167	GFOD1	glucose-fructose oxidoreductase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21096]	-	-	-	-	GO:0005576//extracellular region	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	-	--
ENSG00000145996	3.25	3.964	3.267	3.01	3.193	2.949	211	267	153	146	182	140	CDKAL1	CDK5 regulatory subunit associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:21050]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0035596//methylthiotransferase activity;GO:0035598//N6-threonylcarbomyladenosine methylthiotransferase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0061712//tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase"	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0008150//biological_process;GO:0035600//tRNA methylthiolation;GO:1990145//maintenance of translational fidelity	--
ENSG00000146005	0.352	0.265	0.202	0.187	0.101	0.073	33	25	14	13	8	5	PSD2	pleckstrin and Sec7 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19092]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12494	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000146006	2.997	2.374	2.718	1.74	1.521	1.62	310	257	192	121	132	127	LRRTM2	leucine rich repeat transmembrane neuronal 2 [Source:HGNC Symbol;Acc:HGNC:19409]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding;GO:0042043//neurexin family protein binding	GO:0002091//negative regulation of receptor internalization;GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0060291//long-term synaptic potentiation;GO:0099151//regulation of postsynaptic density assembly	--
ENSG00000146007	29.03	31.877	30.223	27.744	24.134	25.497	872	1019	709	627	653	573	ZMAT2	zinc finger matrin-type 2 [Source:HGNC Symbol;Acc:HGNC:26433]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12848	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000146013	0.052	0.121	0	0	0	0.1	2	5	0	0	0	3	GFRA3	GDNF family receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4245]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0043235//receptor complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0038023//signaling receptor activity	GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007422//peripheral nervous system development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0048485//sympathetic nervous system development;GO:0048666//neuron development	--
ENSG00000146021	7.629	7.009	6.859	5.601	7.279	6.97	1021	992	713	585	800	715	KLHL3	kelch like family member 3 [Source:HGNC Symbol;Acc:HGNC:6354]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0050801//ion homeostasis;GO:0061912//selective autophagy;GO:0070294//renal sodium ion absorption;GO:0070936//protein K48-linked ubiquitination;GO:0072156//distal tubule morphogenesis	--
ENSG00000146038	1.401	1.341	1.713	1.443	1.537	1.6	137	131.86	123.76	104.52	127	113.84	DCDC2	doublecortin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18141]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0034451//centriolar satellite;GO:0042995//cell projection;GO:0060091//kinocilium;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0001764//neuron migration;GO:0006968//cellular defense response;GO:0007399//nervous system development;GO:0007605//sensory perception of sound;GO:0030030//cell projection organization;GO:0030111//regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048813//dendrite morphogenesis;GO:0060271//cilium assembly;GO:1902017//regulation of cilium assembly	--
ENSG00000146039	0	0	0	0	0	0	0	0	0	0	0	0	SLC17A4	solute carrier family 17 member 4 [Source:HGNC Symbol;Acc:HGNC:10932]	-	-	-	-	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005436//sodium:phosphate symporter activity;GO:0015136//sialic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006796//phosphate-containing compound metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0015739//sialic acid transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000146047	0	0	0	0	0	0	0	0	0	0	0	0	H2BC1	H2B clustered histone 1 [Source:HGNC Symbol;Acc:HGNC:18730]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	"GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome"	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	"GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly;GO:0035093//spermatogenesis, exchange of chromosomal proteins"	--
ENSG00000146049	0	0.04	0.2	0.07	0	0.056	0	1.14	4.24	1.48	0	1.16	KAAG1	kidney associated antigen 1 [Source:HGNC Symbol;Acc:HGNC:21031]	-	-	-	-	GO:0005575//cellular_component	-	GO:0006955//immune response	--
ENSG00000146054	0	0.078	0.046	0	0	0	0	2	2	0	0	0	TRIM7	tripartite motif containing 7 [Source:HGNC Symbol;Acc:HGNC:16278]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000146063	6.93	6.228	7.104	8.413	8.115	7.798	496	460	395	453	477	391	TRIM41	tripartite motif containing 41 [Source:HGNC Symbol;Acc:HGNC:19013]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071225//cellular response to muramyl dipeptide	--
ENSG00000146066	99.885	99.743	121.372	141.912	120.498	130.491	1354.97	1359.99	1216	1425.96	1380.99	1287.96	HIGD2A	HIG1 hypoxia inducible domain family member 2A [Source:HGNC Symbol;Acc:HGNC:28311]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	-	GO:0043066//negative regulation of apoptotic process;GO:0097250//mitochondrial respirasome assembly	--
ENSG00000146067	8.397	7.016	7.279	7.288	8.1	7.325	384	374	279	276	342	260	FAM193B	family with sequence similarity 193 member B [Source:HGNC Symbol;Acc:HGNC:25524]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding	-	--
ENSG00000146070	0.138	0.531	0.112	1.699	1.057	0.727	5	21	3	50	34	21	PLA2G7	phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K01062;K01062	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0034362//low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle	"GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0047499//calcium-independent phospholipase A2 activity"	GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0016486//peptide hormone processing;GO:0034374//low-density lipoprotein particle remodeling;GO:0034440//lipid oxidation;GO:0034441//plasma lipoprotein particle oxidation;GO:0034638//phosphatidylcholine catabolic process;GO:0046469//platelet activating factor metabolic process;GO:0050729//positive regulation of inflammatory response;GO:0062234//platelet activating factor catabolic process;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000146072	7.832	9.033	7.19	7.369	7.699	5.935	584	677	396	407	485	322	TNFRSF21	TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05157	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0001783//B cell apoptotic process;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007413//axonal fasciculation;GO:0030889//negative regulation of B cell proliferation;GO:0031642//negative regulation of myelination;GO:0032693//negative regulation of interleukin-10 production;GO:0032696//negative regulation of interleukin-13 production;GO:0032714//negative regulation of interleukin-5 production;GO:0042130//negative regulation of T cell proliferation;GO:0042552//myelination;GO:0048713//regulation of oligodendrocyte differentiation;GO:0050852//T cell receptor signaling pathway;GO:0051402//neuron apoptotic process;GO:0071356//cellular response to tumor necrosis factor;GO:0097252//oligodendrocyte apoptotic process	--
ENSG00000146083	7.729	8.098	8.988	9.744	9.194	12.132	593	603	500	578	618	647	RNF44	ring finger protein 44 [Source:HGNC Symbol;Acc:HGNC:19180]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000146085	13.675	13.001	14.765	12.382	13.357	14.866	1081	1033	862	725	892	855	MMUT	methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K01847;K01847;K01847;K01847;K01847	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0003924//GTPase activity;GO:0004494//methylmalonyl-CoA mutase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0016866//intramolecular transferase activity;GO:0031419//cobalamin binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046906//tetrapyrrole binding;GO:0072341//modified amino acid binding	GO:0009791//post-embryonic development;GO:0043547//positive regulation of GTPase activity;GO:0050667//homocysteine metabolic process	--
ENSG00000146090	0.051	0.152	0.035	0.057	0.139	0	2	6	1	2	5	0	RASGEF1C	RasGEF domain family member 1C [Source:HGNC Symbol;Acc:HGNC:27400]	-	-	-	-	GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000146094	3.22	2.499	2.039	2.024	2.257	2.05	164	130	70	84	115	87	DOK3	docking protein 3 [Source:HGNC Symbol;Acc:HGNC:24583]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction	--
ENSG00000146109	5.324	5.639	6.299	5.949	4.848	6.552	325	346	284	269	250	291	ABT1	activator of basal transcription 1 [Source:HGNC Symbol;Acc:HGNC:17369]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0021522//spinal cord motor neuron differentiation;GO:0034462//small-subunit processome assembly;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000146112	14.028	11.085	9.621	12.835	10.846	9.601	887	792	493	617	649	513	PPP1R18	protein phosphatase 1 regulatory subunit 18 [Source:HGNC Symbol;Acc:HGNC:29413]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019902//phosphatase binding	-	--
ENSG00000146122	78.263	80.513	73.32	83.76	82.761	79.631	9507.35	9751.48	6559.28	7522.28	8469.01	7053.34	DAAM2	dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04512	GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007368//determination of left/right symmetry;GO:0016043//cellular component organization;GO:0016055//Wnt signaling pathway;GO:0021516//dorsal spinal cord development;GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0051489//regulation of filopodium assembly;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090521//glomerular visceral epithelial cell migration;GO:2000050//regulation of non-canonical Wnt signaling pathway	--
ENSG00000146143	3.564	3.13	2.542	2.516	3.172	2.624	159	141	87	86	110	89	PRIM2	DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02685	GO:0005654//nucleoplasm;GO:0005658//alpha DNA polymerase:primase complex	"GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0071667//DNA/RNA hybrid binding"	"GO:0006260//DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006270//DNA replication initiation;GO:1903934//positive regulation of DNA primase activity"	--
ENSG00000146147	2.173	2.574	3.04	4.245	3.582	5.194	50	53	47	55	67	75	MLIP	muscular LMNA interacting protein [Source:HGNC Symbol;Acc:HGNC:21355]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016605//PML body;GO:0031981//nuclear lumen;GO:0042383//sarcolemma	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0005521//lamin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress	--
ENSG00000146151	0.975	1.02	0.749	0.798	0.674	0.584	46	52	28	30	23	19	HMGCLL1	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 [Source:HGNC Symbol;Acc:HGNC:21359]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism"	K01640;K01640;K01640;K01640	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0003824//catalytic activity;GO:0004419//hydroxymethylglutaryl-CoA lyase activity;GO:0016829//lyase activity;GO:0016833//oxo-acid-lyase activity;GO:0046872//metal ion binding	GO:0006552//leucine catabolic process;GO:0006629//lipid metabolic process;GO:0046951//ketone body biosynthetic process	--
ENSG00000146166	0	0	0	0	0	0	0	0	0	0	0	0	LGSN	"lengsin, lens protein with glutamine synthetase domain [Source:HGNC Symbol;Acc:HGNC:21016]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003824//catalytic activity;GO:0004356//glutamate-ammonia ligase activity	GO:0006542//glutamine biosynthetic process;GO:0006807//nitrogen compound metabolic process	--
ENSG00000146192	0	0	0	0	0.026	0	0	0	0	0	1	0	FGD2	"FYVE, RhoGEF and PH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3664]"	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031901//early endosome membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0046847//filopodium assembly;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000146197	0.543	0.675	0.543	0.233	0.299	0.195	88	110	65	28	41	23	SCUBE3	"signal peptide, CUB domain and EGF like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:13655]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0036122//BMP binding;GO:0042802//identical protein binding;GO:0070700//BMP receptor binding	GO:0007165//signal transduction;GO:0030513//positive regulation of BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation	--
ENSG00000146205	0.359	0.398	0.387	0.57	0.383	0.483	34	37	27	21	29	17	ANO7	anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0017128//phospholipid scramblase activity;GO:0046983//protein dimerization activity	GO:0006821//chloride transport;GO:0006869//lipid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0061588//calcium activated phospholipid scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling;GO:0061591//calcium activated galactosylceramide scrambling;GO:1902476//chloride transmembrane transport	--
ENSG00000146215	0.097	0.145	0.275	0.081	0	0	2	3	2	1	0	0	CRIP3	cysteine rich protein 3 [Source:HGNC Symbol;Acc:HGNC:17751]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000146216	0.07	0.073	0.06	0.151	0.109	0.12	8	9	5	15	13	9	TTBK1	tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007611//learning or memory;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021762//substantia nigra development;GO:0032091//negative regulation of protein binding;GO:0032273//positive regulation of protein polymerization;GO:0061890//positive regulation of astrocyte activation;GO:1903980//positive regulation of microglial cell activation;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000146221	0.022	0.046	0.142	0	0.074	0	1.39	2.94	6.72	0	4	0	TCTE1	t-complex-associated-testis-expressed 1 [Source:HGNC Symbol;Acc:HGNC:11693]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030317//flagellated sperm motility	--
ENSG00000146223	16.325	15.843	14.054	13.923	12.802	14.38	965	984	682	555	680	602	RPL7L1	ribosomal protein L7 like 1 [Source:HGNC Symbol;Acc:HGNC:21370]	-	-	-	-	GO:0005730//nucleolus;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0001825//blastocyst formation"	--
ENSG00000146232	4.813	5.95	7.18	6.703	7.159	8.559	201	231	220	197	207	231	NFKBIE	NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Immune system;Nervous system;Immune system;Immune system;Immune system;Cancer: overview;Endocrine system	ko05169//Epstein-Barr virus infection;ko04662//B cell receptor signaling pathway;ko04722//Neurotrophin signaling pathway;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04920//Adipocytokine signaling pathway	K05872;K05872;K05872;K05872;K05872;K05872;K05872;K05872	GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0042942//D-serine transport;GO:0042994//cytoplasmic sequestering of transcription factor	--
ENSG00000146233	4.996	5.069	5.725	3.988	3.895	4.652	252	257	213	149	166	170	CYP39A1	cytochrome P450 family 39 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:17449]	Metabolism	Lipid metabolism	ko00120//Primary bile acid biosynthesis	K07439	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008387//steroid 7-alpha-hydroxylase activity;GO:0008395//steroid hydroxylase activity;GO:0008396//oxysterol 7-alpha-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0033782//24-hydroxycholesterol 7alpha-hydroxylase activity;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006707//cholesterol catabolic process;GO:0007586//digestion;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0042632//cholesterol homeostasis	--
ENSG00000146242	4.376	4.17	3.869	4.369	5.181	4.731	265	251	171	194	262	209	TPBG	trophoblast glycoprotein [Source:HGNC Symbol;Acc:HGNC:12004]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043679//axon terminus	GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0008355//olfactory learning;GO:0050921//positive regulation of chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0051932//synaptic transmission, GABAergic;GO:0051965//positive regulation of synapse assembly;GO:0060326//cell chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072659//protein localization to plasma membrane;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090497//mesenchymal cell migration;GO:0140059//dendrite arborization"	--
ENSG00000146243	2.635	1.552	1.522	1.485	1.289	2.04	294.04	171.06	130	123	126	152	IRAK1BP1	interleukin 1 receptor associated kinase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17368]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006955//immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling	--
ENSG00000146247	3.181	1.822	1.68	1.064	1.426	1.511	786.96	452.94	307	195	298	272	PHIP	pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673]	-	-	-	-	GO:0005634//nucleus	GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0070577//lysine-acetylated histone binding	"GO:0001932//regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0008360//regulation of cell shape;GO:0022604//regulation of cell morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000146250	0.612	1.001	0.321	0.293	0.28	0.596	31	51	12	11	12	22	PRSS35	serine protease 35 [Source:HGNC Symbol;Acc:HGNC:21387]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding	GO:0006508//proteolysis	--
ENSG00000146263	1.229	0.927	0.86	0.508	0.823	0.719	117	105	101	45	91	81	MMS22L	"MMS22 like, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:21475]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035101//FACT complex;GO:0042555//MCM complex;GO:0043596//nuclear replication fork	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing	--
ENSG00000146267	3.348	3.946	2.777	1.779	2.484	2.053	117	133	76	46	82	60	FAXC	"failed axon connections homolog, metaxin like GST domain containing [Source:HGNC Symbol;Acc:HGNC:20742]"	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000146276	0.106	0	0	0	0	0	4	0	0	0	0	0	GABRR1	gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05190;K05190;K05190;K05190;K05190	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0016917//GABA receptor activity;GO:0019904//protein domain specific binding;GO:0030594//neurotransmitter receptor activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0099507//ligand-gated ion channel activity involved in regulation of presynaptic membrane potential;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0099505//regulation of presynaptic membrane potential;GO:1902476//chloride transmembrane transport	--
ENSG00000146278	34.289	32.68	32.187	32.299	35.048	36.432	1365	1318	975	1033	1208	1015	PNRC1	proline rich nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:17278]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000146281	14.27	11.586	13.269	11.279	11.248	16.78	1392	1136	956	815	927	1191	PM20D2	peptidase M20 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21408]	-	-	-	-	GO:0005654//nucleoplasm	GO:0004180//carboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0032268//regulation of cellular protein metabolic process	--
ENSG00000146282	17.101	19.292	17.671	17.716	16.478	16.778	759	840	598	583	629	556	RARS2	"arginyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21406]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01887	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004814//arginine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006420//arginyl-tRNA aminoacylation;GO:0032543//mitochondrial translation	--
ENSG00000146285	0	0	0	0	0	0	0	0	0	0	0	0	SCML4	Scm polycomb group protein like 4 [Source:HGNC Symbol;Acc:HGNC:21397]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000146350	2	1.146	1.01	0.76	1.701	1.374	115	68	64	54	69	53	TBC1D32	TBC1 domain family member 32 [Source:HGNC Symbol;Acc:HGNC:21485]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001822//kidney development;GO:0002088//lens development in camera-type eye;GO:0003406//retinal pigment epithelium development;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0021532//neural tube patterning;GO:0021915//neural tube development;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0060021//roof of mouth development;GO:0060041//retina development in camera-type eye;GO:0060271//cilium assembly;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0061512//protein localization to cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000146352	0	0	0	0.006	0	0	0	0	0	1	0	0	CLVS2	clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0007040//lysosome organization	--
ENSG00000146360	0	0	0	0	0	0	0	0	0	0	0	0	GPR6	G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:4515]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0038036//sphingosine-1-phosphate receptor activity	GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019222//regulation of metabolic process	--
ENSG00000146373	4.471	3.678	3.782	3.228	3.456	4.384	727	456	319	257	354	371	RNF217	ring finger protein 217 [Source:HGNC Symbol;Acc:HGNC:21487]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000146374	0.841	0.864	0.74	0.304	0.451	0.206	84	63	45	17	29	15	RSPO3	R-spondin 3 [Source:HGNC Symbol;Acc:HGNC:20866]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K23098	GO:0005576//extracellular region	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0008201//heparin binding	"GO:0001525//angiogenesis;GO:0001974//blood vessel remodeling;GO:0002040//sprouting angiogenesis;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0050896//response to stimulus;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000146376	13.751	11.464	12.689	10.012	9.877	12.294	1259	1055	858	679	764	819	ARHGAP18	Rho GTPase activating protein 18 [Source:HGNC Symbol;Acc:HGNC:21035]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0005096//GTPase activator activity;GO:0045296//cadherin binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0030833//regulation of actin filament polymerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:2000145//regulation of cell motility	--
ENSG00000146378	0	0	0	0	0	0	0	0	0	0	0	0	TAAR2	trace amine associated receptor 2 [Source:HGNC Symbol;Acc:HGNC:4514]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000146383	0	0	0	0	0	0	0	0	0	0	0	0	TAAR6	trace amine associated receptor 6 [Source:HGNC Symbol;Acc:HGNC:20978]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000146385	0	0	0	0	0	0	0	0	0	0	0	0	TAAR8	trace amine associated receptor 8 [Source:HGNC Symbol;Acc:HGNC:14964]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000146386	20.961	18.892	21.989	24.22	23.205	28.894	340	308	262	291	318	341	ABRACL	ABRA C-terminal like [Source:HGNC Symbol;Acc:HGNC:21230]	-	-	-	-	-	-	GO:0032970//regulation of actin filament-based process	--
ENSG00000146399	0	0	0	0	0	0	0	0	0	0	0	0	TAAR1	trace amine associated receptor 1 [Source:HGNC Symbol;Acc:HGNC:17734]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008227//G protein-coupled amine receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000146409	6.72	6.115	6.817	6.611	6.679	7.646	340	311	256	249	287	281	SLC18B1	solute carrier family 18 member B1 [Source:HGNC Symbol;Acc:HGNC:21573]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000146410	0.158	0.133	0.214	0.234	0.112	0.159	5	3	5	3	3	2	MTFR2	mitochondrial fission regulator 2 [Source:HGNC Symbol;Acc:HGNC:21115]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0000266//mitochondrial fission;GO:0007005//mitochondrion organization;GO:0009060//aerobic respiration	--
ENSG00000146411	84.226	75.453	79.32	58.157	64.281	68.175	9734.36	8765.21	6770.66	4978.8	6276.66	5733.01	SLC2A12	solute carrier family 2 member 12 [Source:HGNC Symbol;Acc:HGNC:18067]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0022857//transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000146414	3.21	2.393	3.228	2.19	2.222	2.771	489	361	266	245	287	311	SHPRH	SNF2 histone linker PHD RING helicase [Source:HGNC Symbol;Acc:HGNC:19336]	-	-	-	-	GO:0000786//nucleosome;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006807//nitrogen compound metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0043170//macromolecule metabolic process	--
ENSG00000146416	19.159	21.995	25.715	22.597	21.888	19.67	723	871	595	581	691	558	AIG1	androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:21607]	-	-	-	-	GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0042758//long-chain fatty acid catabolic process	--
ENSG00000146425	41.673	45.862	41.223	33.435	32.675	40.664	631	698	461	375	418	448	DYNLT1	dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K10420	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0030286//dynein complex;GO:0034774//secretory granule lumen;GO:0043657//host cell;GO:0099503//secretory vesicle;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045505//dynein intermediate chain binding	GO:0000132//establishment of mitotic spindle orientation;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0019060//intracellular transport of viral protein in host cell;GO:0046718//viral entry into host cell;GO:0050768//negative regulation of neurogenesis;GO:0051301//cell division;GO:0075521//microtubule-dependent intracellular transport of viral material towards nucleus;GO:0075606//transport of viral material towards nucleus	--
ENSG00000146426	13.284	13.206	14.851	13.212	12.696	13.05	803.58	809.6	664.42	577.94	643.95	574.94	TIAM2	TIAM Rac1 associated GEF 2 [Source:HGNC Symbol;Acc:HGNC:11806]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0035556//intracellular signal transduction;GO:0050772//positive regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000146433	10.824	9.585	9.89	9.196	9.136	10.076	1148	1024	775	721	817	776	TMEM181	transmembrane protein 181 [Source:HGNC Symbol;Acc:HGNC:20958]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015643//toxic substance binding	-	--
ENSG00000146453	0.027	0	0	0	0	0.037	1	0	0	0	0	1	PNLDC1	PARN like ribonuclease domain containing exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:21185]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K01148	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0001825//blastocyst formation;GO:0007283//spermatogenesis;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1990511//piRNA biosynthetic process"	--
ENSG00000146457	32.268	34.439	34.294	27.641	28.042	31.786	1276	1376	972	817	947	908.98	WTAP	WT1 associated protein [Source:HGNC Symbol;Acc:HGNC:16846]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0080009//mRNA methylation"	--
ENSG00000146463	19.207	13.918	14.285	11.422	12.939	13.309	2519	2077	1439	1238	1605	1423	ZMYM4	zinc finger MYM-type containing 4 [Source:HGNC Symbol;Acc:HGNC:13055]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0007275//multicellular organism development;GO:0022604//regulation of cell morphogenesis	--
ENSG00000146469	0	0	0	0	0	0	0	0	0	0	0	0	VIP	vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway	K05264;K05264	GO:0005576//extracellular region;GO:0043005//neuron projection;GO:0043204//perikaryon	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0051428//peptide hormone receptor binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007589//body fluid secretion;GO:0007611//learning or memory;GO:0008284//positive regulation of cell population proliferation;GO:0032812//positive regulation of epinephrine secretion;GO:0032880//regulation of protein localization;GO:0043066//negative regulation of apoptotic process;GO:0043267//negative regulation of potassium ion transport;GO:0045732//positive regulation of protein catabolic process;GO:0048242//epinephrine secretion;GO:0048255//mRNA stabilization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051930//regulation of sensory perception of pain;GO:0060406//positive regulation of penile erection;GO:0070459//prolactin secretion	--
ENSG00000146476	13.355	9.945	12.064	12.436	10.665	15.854	664	497	443	458	448	574	ARMT1	acidic residue methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17872]	-	-	-	-	-	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008983//protein-glutamate O-methyltransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0051998//protein carboxyl O-methyltransferase activity;GO:0097023//fructose 6-phosphate aldolase activity;GO:0103026//fructose-1-phosphatase activity	GO:0006479//protein methylation;GO:0006974//cellular response to DNA damage stimulus;GO:0016311//dephosphorylation;GO:0032259//methylation;GO:2001020//regulation of response to DNA damage stimulus	--
ENSG00000146477	0.969	1.009	1.029	0.805	1.323	0.983	65	68	51	40	75	48	SLC22A3	solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K08200	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0098793//presynapse	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0001692//histamine metabolic process;GO:0006811//ion transport;GO:0006836//neurotransmitter transport;GO:0006837//serotonin transport;GO:0015695//organic cation transport;GO:0015697//quaternary ammonium group transport;GO:0015711//organic anion transport;GO:0015718//monocarboxylic acid transport;GO:0015844//monoamine transport;GO:0015850//organic hydroxy compound transport;GO:0015872//dopamine transport;GO:0032098//regulation of appetite;GO:0042908//xenobiotic transport;GO:0051608//histamine transport;GO:0051610//serotonin uptake;GO:0051615//histamine uptake;GO:0051620//norepinephrine uptake;GO:0051625//epinephrine uptake;GO:0055085//transmembrane transport;GO:0072530//purine-containing compound transmembrane transport;GO:0090494//dopamine uptake;GO:0150104//transport across blood-brain barrier;GO:1901998//toxin transport	--
ENSG00000146530	0.594	0.34	0.181	0.162	0.109	0.203	59	37	14	13	10	16	VWDE	von Willebrand factor D and EGF domains [Source:HGNC Symbol;Acc:HGNC:21897]	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding	GO:0048856//anatomical structure development	--
ENSG00000146535	18.365	20.193	18.596	17.387	18.159	15.963	1645	1839	1227	1164	1382	1038	GNA12	G protein subunit alpha 12 [Source:HGNC Symbol;Acc:HGNC:4380]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Circulatory system;Signal transduction;Endocrine system;Nervous system	"ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04071//Sphingolipid signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04730//Long-term depression"	K04346;K04346;K04346;K04346;K04346;K04346;K04346;K04346;K04346;K04346;K04346	GO:0005737//cytoplasm;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0031526//brush border membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0019888//protein phosphatase regulator activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0031752//D5 dopamine receptor binding;GO:0046872//metal ion binding;GO:0051721//protein phosphatase 2A binding	GO:0001701//in utero embryonic development;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007596//blood coagulation;GO:0008217//regulation of blood pressure;GO:0008360//regulation of cell shape;GO:0009410//response to xenobiotic stimulus;GO:0010259//multicellular organism aging;GO:0010762//regulation of fibroblast migration;GO:0030154//cell differentiation;GO:0032006//regulation of TOR signaling;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035556//intracellular signal transduction;GO:0042733//embryonic digit morphogenesis;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration	--
ENSG00000146540	21.033	24.598	25.201	31.468	25.082	20.432	530	641	470	587	520	387	C7orf50	chromosome 7 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:22421]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000146555	1.185	1.412	2.036	1.168	1.244	1.377	218	257	219	158	185	184	SDK1	sidekick cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:19307]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0010842//retina layer formation;GO:0048148//behavioral response to cocaine;GO:0060998//regulation of dendritic spine development	--
ENSG00000146574	29.131	24.338	27.467	23.366	19.76	21.311	1096.1	920.45	764.14	651.23	628.13	583.99	CCZ1B	"CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated [Source:HGNC Symbol;Acc:HGNC:21717]"	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0035658//Mon1-Ccz1 complex;GO:0043231//intracellular membrane-bounded organelle	-	GO:0016192//vesicle-mediated transport	--
ENSG00000146576	9.386	10.995	11.307	10.253	12.516	14.163	424	486	373	335	457	432	C7orf26	chromosome 7 open reading frame 26 [Source:HGNC Symbol;Acc:HGNC:21702]	-	-	-	-	-	-	-	--
ENSG00000146587	3.269	2.042	1.787	1.664	1.774	2.102	448.06	278	181	169	205.55	209.75	RBAK	RB associated KRAB zinc finger [Source:HGNC Symbol;Acc:HGNC:17680]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000146592	0.209	0.208	0.135	0.148	0.136	0.155	37	26	11	9	14	14	CREB5	cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047;K09047	GO:0000785//chromatin;GO:0005634//nucleus;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	TF_bZIP
ENSG00000146618	0	0	0	0	0	0	0	0	0	0	0	0	FERD3L	Fer3 like bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:16660]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032502//developmental process;GO:0033504//floor plate development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048468//cell development;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000146648	26.135	27.578	16.95	9.495	12.525	11.024	5362	5695	2572	1445	2174	1648	EGFR	epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Cancer: overview;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Endocrine system;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cellular community - eukaryotes;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05131//Shigellosis;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04915//Estrogen signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04066//HIF-1 signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05213//Endometrial cancer;ko05219//Bladder cancer"	K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361;K04361	"GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0031965//nuclear membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070435//Shc-EGFR complex;GO:0097489//multivesicular body, internal vesicle lumen;GO:0097708//intracellular vesicle;GO:0098590//plasma membrane region"	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0004672//protein kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005006//epidermal growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019903//protein phosphatase binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0048408//epidermal growth factor binding;GO:0051015//actin filament binding;GO:0051117//ATPase binding	"GO:0000165//MAPK cascade;GO:0000902//cell morphogenesis;GO:0001503//ossification;GO:0001892//embryonic placenta development;GO:0001934//positive regulation of protein phosphorylation;GO:0001942//hair follicle development;GO:0006468//protein phosphorylation;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007435//salivary gland morphogenesis;GO:0007611//learning or memory;GO:0008284//positive regulation of cell population proliferation;GO:0008544//epidermis development;GO:0010750//positive regulation of nitric oxide mediated signal transduction;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021795//cerebral cortex cell migration;GO:0030154//cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0034614//cellular response to reactive oxygen species;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0042327//positive regulation of phosphorylation;GO:0043006//activation of phospholipase A2 activity by calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045739//positive regulation of DNA repair;GO:0045740//positive regulation of DNA replication;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046328//regulation of JNK cascade;GO:0046718//viral entry into host cell;GO:0046777//protein autophosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0048546//digestive tract morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050896//response to stimulus;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051205//protein insertion into membrane;GO:0051897//positive regulation of protein kinase B signaling;GO:0060571//morphogenesis of an epithelial fold;GO:0061029//eyelid development in camera-type eye;GO:0070141//response to UV-A;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071230//cellular response to amino acid stimulus;GO:0071276//cellular response to cadmium ion;GO:0071363//cellular response to growth factor stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:1900020//positive regulation of protein kinase C activity;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:1905208//negative regulation of cardiocyte differentiation"	--
ENSG00000146670	2.739	1.708	1.82	1.552	1.173	0.858	90	64	69	59	44	30	CDCA5	cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17390	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0000278//mitotic cell cycle;GO:0006302//double-strand break repair;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0007076//mitotic chromosome condensation;GO:0007080//mitotic metaphase plate congression;GO:0031536//positive regulation of exit from mitosis;GO:0051301//cell division;GO:0071922//regulation of cohesin loading	--
ENSG00000146674	14.999	21.331	13.215	10.676	11.996	7.871	813	1148	529	401	542	309	IGFBP3	insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472]	Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes	Cancer: overview;Cell growth and death;Endocrine system;Cell growth and death	"ko05202//Transcriptional misregulation in cancer;ko04218//Cellular senescence;ko04935//Growth hormone synthesis, secretion and action;ko04115//p53 signaling pathway"	K10138;K10138;K10138;K10138	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0016942//insulin-like growth factor binding protein complex;GO:0042567//insulin-like growth factor ternary complex	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0008160//protein tyrosine phosphatase activator activity;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding;GO:0046872//metal ion binding	GO:0001558//regulation of cell growth;GO:0001649//osteoblast differentiation;GO:0001933//negative regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0009968//negative regulation of signal transduction;GO:0010906//regulation of glucose metabolic process;GO:0014912//negative regulation of smooth muscle cell migration;GO:0040008//regulation of growth;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0044342//type B pancreatic cell proliferation;GO:0045663//positive regulation of myoblast differentiation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050790//regulation of catalytic activity	--
ENSG00000146676	6.089	5.149	4.737	3.673	4.469	4.371	1166	991	670	521	723	609	PURB	purine rich element binding protein B [Source:HGNC Symbol;Acc:HGNC:9702]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0032422//purine-rich negative regulatory element binding;GO:0046332//SMAD binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation;GO:0030154//cell differentiation;GO:0045637//regulation of myeloid cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	Others
ENSG00000146678	0	0	0	0	0	0	0	0	0	0	0	0	IGFBP1	insulin like growth factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:5469]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding	GO:0007165//signal transduction;GO:0007568//aging;GO:0008286//insulin receptor signaling pathway;GO:0030307//positive regulation of cell growth;GO:0042246//tissue regeneration;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000146700	0.747	1.011	1.306	1.534	1.671	1.893	43.38	59	56	66	82	80	SSC4D	scavenger receptor cysteine rich family member with 4 domains [Source:HGNC Symbol;Acc:HGNC:14461]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane	GO:0005044//scavenger receptor activity	GO:0006897//endocytosis	--
ENSG00000146701	69.439	72.71	76.081	80.131	76.512	79.319	3103	3274	2496	2665	2890	2586	MDH2	malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:6971]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00020//Citrate cycle (TCA cycle)	K00026;K00026;K00026;K00026;K00026;K00026	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity;GO:0016615//malate dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030060//L-malate dehydrogenase activity;GO:0043621//protein self-association;GO:0046554//malate dehydrogenase (NADP+) activity"	GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006108//malate metabolic process;GO:0006734//NADH metabolic process;GO:0009060//aerobic respiration;GO:0019752//carboxylic acid metabolic process	--
ENSG00000146707	9.627	9.23	10.49	11.295	7.843	9.488	296.75	288.71	245.89	260.14	210.01	214.34	POMZP3	POM121 and ZP3 fusion [Source:HGNC Symbol;Acc:HGNC:9203]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0031012//extracellular matrix;GO:0031965//nuclear membrane;GO:0035805//egg coat	GO:0003674//molecular_function;GO:0032190//acrosin binding;GO:0035804//structural constituent of egg coat	GO:0007339//binding of sperm to zona pellucida;GO:0008150//biological_process;GO:0035803//egg coat formation;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000146729	27.792	25.52	25.918	23.15	22.053	27.345	1131	1025	773	675	761	817	NIPSNAP2	nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0006119//oxidative phosphorylation;GO:0007005//mitochondrion organization;GO:1901843//positive regulation of high voltage-gated calcium channel activity	--
ENSG00000146731	53.761	53.4	51.746	49.059	48.212	52.309	2880	2875	2046	1947	2182	2039	CCT6A	chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005874//microtubule;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0071987//WD40-repeat domain binding	GO:0006457//protein folding;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000146733	8.744	9.407	10.071	7.742	7.229	8.417	242	250	192	176	169	217	PSPH	phosphoserine phosphatase [Source:HGNC Symbol;Acc:HGNC:9577]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00260//Glycine, serine and threonine metabolism"	K01079;K01079;K01079;K01079	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043005//neuron projection	GO:0000287//magnesium ion binding;GO:0016787//hydrolase activity;GO:0036424//L-phosphoserine phosphatase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0006563//L-serine metabolic process;GO:0006564//L-serine biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0016311//dephosphorylation;GO:0031667//response to nutrient levels;GO:0033574//response to testosterone	--
ENSG00000146755	0	0	0	0	0	0	0	0	0	0	0	0	TRIM50	tripartite motif containing 50 [Source:HGNC Symbol;Acc:HGNC:19017]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000146757	13.145	11.146	9.366	9.382	9.143	8.667	852	726	451	453.18	500	414	ZNF92	zinc finger protein 92 [Source:HGNC Symbol;Acc:HGNC:13168]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000146776	1.5	1.84	1.679	1.195	1.532	1.291	95	120	90	60	84	71	ATXN7L1	ataxin 7 like 1 [Source:HGNC Symbol;Acc:HGNC:22210]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000146802	8.708	7.565	7.732	9.07	8.062	8.599	700	637	533	479	531	528	TMEM168	transmembrane protein 168 [Source:HGNC Symbol;Acc:HGNC:25826]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle	-	-	--
ENSG00000146809	0	0	0	0	0	0	0	0	0	0	0	0	ASB15	ankyrin repeat and SOCS box containing 15 [Source:HGNC Symbol;Acc:HGNC:19767]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification	--
ENSG00000146826	2.62	3.687	4.058	3.046	3.909	3.463	133	189	146	115.6	162	123	TRAPPC14	trafficking protein particle complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:25604]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0072686//mitotic spindle;GO:1990071//TRAPPII protein complex	GO:0005515//protein binding;GO:0043014//alpha-tubulin binding	GO:0030030//cell projection organization;GO:0042127//regulation of cell population proliferation;GO:0060271//cilium assembly	--
ENSG00000146828	8.323	9.253	9.297	13.369	11.079	9.315	485	569	426	541	561	421	SLC12A9	solute carrier family 12 member 9 [Source:HGNC Symbol;Acc:HGNC:17435]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006884//cell volume homeostasis;GO:0015698//inorganic anion transport;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000146830	7.275	7.356	8.822	7.278	8.327	8.204	954	974	842	708	927	778	GIGYF1	GRB10 interacting GYF protein 1 [Source:HGNC Symbol;Acc:HGNC:9126]	-	-	-	-	GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0008150//biological_process;GO:0048009//insulin-like growth factor receptor signaling pathway	--
ENSG00000146833	4.349	4.916	6.302	4.183	4.855	5.088	296	336	249	213	281	250	TRIM4	tripartite motif containing 4 [Source:HGNC Symbol;Acc:HGNC:16275]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000146834	20.27	22.612	21.659	27.521	26.853	21.62	1015	1077	781	993.67	1052	827	MEPCE	methylphosphate capping enzyme [Source:HGNC Symbol;Acc:HGNC:20247]	-	-	-	-	GO:0005634//nucleus;GO:0120259//7SK snRNP;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0017069//snRNA binding;GO:0097322//7SK snRNA binding;GO:1990276//RNA 5'-methyltransferase activity	GO:0001510//RNA methylation;GO:0016073//snRNA metabolic process;GO:0032259//methylation;GO:0040031//snRNA modification;GO:1904871//positive regulation of protein localization to Cajal body;GO:1905382//positive regulation of snRNA transcription by RNA polymerase II	--
ENSG00000146839	0	0	0	0	0	0	0	0	0	0	0	0	ZAN	zonadhesin [Source:HGNC Symbol;Acc:HGNC:12857]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007339//binding of sperm to zona pellucida;GO:0098609//cell-cell adhesion	--
ENSG00000146842	13.366	12.845	10.757	8.781	11.146	10.841	831	840.05	536	424	592	516	TMEM209	transmembrane protein 209 [Source:HGNC Symbol;Acc:HGNC:21898]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000146856	0	0	0.214	0.026	0	0.133	0	0	3	1	0	1	AGBL3	AGBL carboxypeptidase 3 [Source:HGNC Symbol;Acc:HGNC:27981]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0035610//protein side chain deglutamylation	--
ENSG00000146857	0	0	0	0	0	0	0	0	0	0	0	0	STRA8	stimulated by retinoic acid 8 [Source:HGNC Symbol;Acc:HGNC:30653]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046983//protein dimerization activity	GO:0006260//DNA replication;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048133//male germ-line stem cell asymmetric division;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0071300//cellular response to retinoic acid;GO:0090427//activation of meiosis	--
ENSG00000146858	1.447	2.146	1.515	1.511	2.036	2.852	53	79	41	41	63	76	ZC3HAV1L	"zinc finger CCCH-type containing, antiviral 1 like [Source:HGNC Symbol;Acc:HGNC:22423]"	-	-	-	-	GO:0005829//cytosol	-	-	--
ENSG00000146859	9.119	7.859	8.585	10.721	9.782	9.164	377.73	327.19	262.65	328.96	342.32	276.19	TMEM140	transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000146872	15.581	11.503	14.02	12.032	11.046	12.752	1101	910	711	606	702	671	TLK2	tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC:11842]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0001672//regulation of chromatin assembly or disassembly;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0010507//negative regulation of autophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035556//intracellular signal transduction;GO:0071480//cellular response to gamma radiation	--
ENSG00000146904	0.146	0.261	0.197	0.374	0.465	0.5	10	18	10	19	27	25	EPHA1	EPH receptor A1 [Source:HGNC Symbol;Acc:HGNC:3385]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05102	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0001968//fibronectin binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding	GO:0001525//angiogenesis;GO:0001954//positive regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0033674//positive regulation of kinase activity;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043087//regulation of GTPase activity;GO:0045766//positive regulation of angiogenesis;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0090630//activation of GTPase activity	--
ENSG00000146909	2.061	1.625	2.34	1.958	1.811	1.95	260	206	218	183	193	179	NOM1	nucleolar protein with MIF4G domain 1 [Source:HGNC Symbol;Acc:HGNC:13244]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0008150//biological_process;GO:0042274//ribosomal small subunit biogenesis;GO:0048820//hair follicle maturation	--
ENSG00000146910	0	0	0	0	0	0.008	0	0	0	0	0	0.3	CNPY1	canopy FGF signaling regulator 1 [Source:HGNC Symbol;Acc:HGNC:27786]	-	-	-	-	GO:0005783//endoplasmic reticulum	-	-	--
ENSG00000146918	2.805	2.479	2.087	1.751	1.991	1.996	236	210	131.06	108	143	121	NCAPG2	non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0030293//transmembrane receptor protein tyrosine kinase inhibitor activity;GO:0035033//histone deacetylase regulator activity;GO:0035064//methylated histone binding;GO:0043425//bHLH transcription factor binding	GO:0000070//mitotic sister chromatid segregation;GO:0001833//inner cell mass cell proliferation;GO:0006366//transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0030218//erythrocyte differentiation;GO:0030261//chromosome condensation;GO:0031063//regulation of histone deacetylation;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000146926	0	0	0	0	0	0	0	0	0	0	0	0	ASB10	ankyrin repeat and SOCS box containing 10 [Source:HGNC Symbol;Acc:HGNC:17185]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification	--
ENSG00000146938	1.715	2.167	1.602	1.696	1.591	1.891	200.78	197.32	137.65	115.47	146.32	113.34	NLGN4X	neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07378	"GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0089717//spanning component of membrane;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane;GO:0098983//symmetric, GABA-ergic, inhibitory synapse;GO:0098984//neuron to neuron synapse;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0005515//protein binding;GO:0031404//chloride ion binding;GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding;GO:0097110//scaffold protein binding	GO:0003360//brainstem development;GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007612//learning;GO:0021549//cerebellum development;GO:0030182//neuron differentiation;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0035265//organ growth;GO:0045216//cell-cell junction organization;GO:0048488//synaptic vesicle endocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0071625//vocalization behavior;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0099054//presynapse assembly	--
ENSG00000146950	12.366	13.111	13.304	12.378	12.067	11.685	1784	1898	1441	1305	1560	1305	SHROOM2	shroom family member 2 [Source:HGNC Symbol;Acc:HGNC:630]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0043296//apical junction complex;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0015280//ligand-gated sodium channel activity;GO:0051015//actin filament binding	GO:0002089//lens morphogenesis in camera-type eye;GO:0007015//actin filament organization;GO:0007420//brain development;GO:0008057//eye pigment granule organization;GO:0016477//cell migration;GO:0032401//establishment of melanosome localization;GO:0032438//melanosome organization;GO:0035725//sodium ion transmembrane transport;GO:0043010//camera-type eye development;GO:0043482//cellular pigment accumulation;GO:0043583//ear development;GO:0045176//apical protein localization;GO:0048593//camera-type eye morphogenesis	--
ENSG00000146955	0.072	0.151	0.159	0.197	0.021	0.149	4	5	2	5	1	6	RAB19	"RAB19, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:19982]"	-	-	-	-	GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport	--
ENSG00000146963	14.735	19.998	16.241	12.288	16.091	19.727	801.15	988.02	579.49	491.86	671.65	741.24	LUC7L2	"LUC7 like 2, pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:21608]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005685//U1 snRNP;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0006376//mRNA splice site selection	--
ENSG00000146966	55.072	56.904	46.339	32.226	36.609	35.917	3671	3740	2344	1644	2156	1549	DENND2A	DENN domain containing 2A [Source:HGNC Symbol;Acc:HGNC:22212]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity	"GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0050790//regulation of catalytic activity"	--
ENSG00000147003	75.05	65.63	71.266	46.687	47.55	63.872	2105.29	1849.94	1476.36	969.8	1126.58	1303.6	CLTRN	"collectrin, amino acid transport regulator [Source:HGNC Symbol;Acc:HGNC:29437]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0017156//calcium-ion regulated exocytosis;GO:0022898//regulation of transmembrane transporter activity;GO:0035493//SNARE complex assembly;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0051957//positive regulation of amino acid transport;GO:1905737//positive regulation of L-proline import across plasma membrane	--
ENSG00000147010	56.464	52.622	52.229	40.102	41.184	47.996	3855	3593	2572	2053	2415	2454	SH3KBP1	SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12470	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0017124//SH3 domain binding;GO:0031625//ubiquitin protein ligase binding	GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0050871//positive regulation of B cell activation	--
ENSG00000147027	20.382	17.453	15.204	18.736	18.588	22.322	1708	1470	941	1163	1316	1361	TMEM47	transmembrane protein 47 [Source:HGNC Symbol;Acc:HGNC:18515]	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0098609//cell-cell adhesion	--
ENSG00000147036	0.005	0.111	0.006	0.006	0.017	0.007	1	6	1	1	3	1	LANCL3	LanC like 3 [Source:HGNC Symbol;Acc:HGNC:24767]	-	-	-	-	GO:0005886//plasma membrane	-	GO:0005975//carbohydrate metabolic process	--
ENSG00000147041	0.69	0.707	0.289	0.969	0.637	0.725	68	70	21	70	53	52	SYTL5	synaptotagmin like 5 [Source:HGNC Symbol;Acc:HGNC:15589]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070382//exocytic vesicle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0031267//small GTPase binding;GO:0042043//neurexin family protein binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis	--
ENSG00000147044	12.523	11.318	10.647	8.65	10.811	10.657	1128	963	707	541	744	647	CASK	calcium/calmodulin dependent serine protein kinase [Source:HGNC Symbol;Acc:HGNC:1497]	-	-	-	-	GO:0005604//basement membrane;GO:0005634//nucleus;GO:0005652//nuclear lamina;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0031982//vesicle;GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0060170//ciliary membrane;GO:0098685//Schaffer collateral - CA1 synapse	GO:0000166//nucleotide binding;GO:0004385//guanylate kinase activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042043//neurexin family protein binding;GO:0106310//protein serine kinase activity	GO:0001953//negative regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016310//phosphorylation;GO:0034613//cellular protein localization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process;GO:0046928//regulation of neurotransmitter secretion;GO:0051179//localization;GO:0061045//negative regulation of wound healing;GO:0070509//calcium ion import;GO:0090280//positive regulation of calcium ion import;GO:0090288//negative regulation of cellular response to growth factor stimulus;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000147050	6.541	6.217	5.266	5.004	5.744	5.127	721	680	398	404	525	401	KDM6A	lysine demethylase 6A [Source:HGNC Symbol;Acc:HGNC:12637]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K11447	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0044666//MLL3/4 complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032452//histone demethylase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0071558//histone H3-tri/di-methyl-lysine-27 demethylase activity	GO:0001701//in utero embryonic development;GO:0001843//neural tube closure;GO:0003007//heart morphogenesis;GO:0003016//respiratory system process;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007507//heart development;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0021915//neural tube development;GO:0032525//somite rostral/caudal axis specification;GO:0035264//multicellular organism growth;GO:0048333//mesodermal cell differentiation;GO:0048568//embryonic organ development;GO:0048570//notochord morphogenesis;GO:0051568//histone H3-K4 methylation;GO:0060070//canonical Wnt signaling pathway;GO:0071557//histone H3-K27 demethylation;GO:0072359//circulatory system development	--
ENSG00000147059	0.517	0.761	0.679	0	0.581	0.634	12.55	21.95	11.35	0	14	11.83	SPIN2A	spindlin family member 2A [Source:HGNC Symbol;Acc:HGNC:20694]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007276//gamete generation;GO:0051726//regulation of cell cycle"	--
ENSG00000147065	111.008	114.256	108.087	111.485	111.68	98.238	9118	9433	6557	6783	7750	5858	MSN	moesin [Source:HGNC Symbol;Acc:HGNC:7373]	Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems	Cell motility;Cancer: overview;Cellular community - eukaryotes;Infectious disease: viral;Immune system	ko04810//Regulation of actin cytoskeleton;ko05205//Proteoglycans in cancer;ko04530//Tight junction;ko05162//Measles;ko04670//Leukocyte transendothelial migration	K05763;K05763;K05763;K05763;K05763	GO:0001931//uropod;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030175//filopodium;GO:0031143//pseudopodium;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0072562//blood microparticle	GO:0003725//double-stranded RNA binding;GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0050839//cell adhesion molecule binding	GO:0001771//immunological synapse formation;GO:0007010//cytoskeleton organization;GO:0007159//leukocyte cell-cell adhesion;GO:0008360//regulation of cell shape;GO:0008361//regulation of cell size;GO:0010628//positive regulation of gene expression;GO:0022612//gland morphogenesis;GO:0022614//membrane to membrane docking;GO:0042098//T cell proliferation;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0050900//leukocyte migration;GO:0061028//establishment of endothelial barrier;GO:0070489//T cell aggregation;GO:0071394//cellular response to testosterone stimulus;GO:0071803//positive regulation of podosome assembly;GO:0072678//T cell migration;GO:1902115//regulation of organelle assembly;GO:1902966//positive regulation of protein localization to early endosome;GO:1903364//positive regulation of cellular protein catabolic process;GO:2000401//regulation of lymphocyte migration;GO:2000643//positive regulation of early endosome to late endosome transport	--
ENSG00000147081	0	0	0	0	0	0	0	0	0	0	0	0	AKAP4	A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005952//cAMP-dependent protein kinase complex;GO:0030018//Z disc;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0097224//sperm connecting piece;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097229//sperm end piece;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0051018//protein kinase A binding	GO:0007165//signal transduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007338//single fertilization;GO:0008104//protein localization;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility;GO:0044458//motile cilium assembly;GO:0045184//establishment of protein localization	--
ENSG00000147082	0.128	0.128	0.056	0.159	0.175	0.088	12	12	4	11	7	6	CCNB3	cyclin B3 [Source:HGNC Symbol;Acc:HGNC:18709]	Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems	Infectious disease: viral;Cell growth and death;Signal transduction;Cell growth and death;Endocrine system	ko05170//Human immunodeficiency virus 1 infection;ko04218//Cellular senescence;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K21771;K21771;K21771;K21771;K21771	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007049//cell cycle;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051321//meiotic cell cycle	--
ENSG00000147099	14.006	12.52	9.08	11.161	11.59	11.279	465.68	412.97	240.84	317	363.33	310	HDAC8	histone deacetylase 8 [Source:HGNC Symbol;Acc:HGNC:13315]	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11405;K11405;K11405	GO:0000118//histone deacetylase complex;GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030544//Hsp70 protein binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007062//sister chromatid cohesion;GO:0016575//histone deacetylation;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032204//regulation of telomere maintenance;GO:0071922//regulation of cohesin loading	--
ENSG00000147100	16.561	17.106	18.523	15.837	15.842	14.962	1418	1426	1118	979	1146	923	SLC16A2	solute carrier family 16 member 2 [Source:HGNC Symbol;Acc:HGNC:10923]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K08231	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005215//transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015349//thyroid hormone transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006520//cellular amino acid metabolic process;GO:0006590//thyroid hormone generation;GO:0015718//monocarboxylic acid transport;GO:0042403//thyroid hormone metabolic process;GO:0055085//transmembrane transport;GO:0070327//thyroid hormone transport;GO:0070460//thyroid-stimulating hormone secretion;GO:0089718//amino acid import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000147113	0	0	0	0	0	0	0	0	0	0	0	0	DIPK2B	divergent protein kinase domain 2B [Source:HGNC Symbol;Acc:HGNC:25866]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000147117	0.211	0.343	0.234	0.129	0.318	0.105	11	18	9	5	14	4	ZNF157	zinc finger protein 157 [Source:HGNC Symbol;Acc:HGNC:12942]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000147118	1.781	1.704	1.25	0.853	1.447	1.553	130	126	67	47	89	83	ZNF182	zinc finger protein 182 [Source:HGNC Symbol;Acc:HGNC:13001]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000147119	0.382	0.52	0.545	0.896	0.524	0.608	19	26	20	33	22	22	CHST7	carbohydrate sulfotransferase 7 [Source:HGNC Symbol;Acc:HGNC:13817]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K04743	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0008459//chondroitin 6-sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0005976//polysaccharide metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000147121	4.047	3.554	3.44	4.748	3.276	2.72	129.54	107.77	83.06	110.91	93.27	69.2	KRBOX4	KRAB box domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26007]	-	-	-	-	-	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000147123	89.717	92.256	101.473	117.241	94.499	95.488	1197.33	1256.8	1006.35	1158.12	1060.85	937	NDUFB11	NADH:ubiquinone oxidoreductase subunit B11 [Source:HGNC Symbol;Acc:HGNC:20372]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351;K11351	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding	GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000147124	3.593	2.778	2.41	2.633	2.306	3.206	326	285	181	185	195	210	ZNF41	zinc finger protein 41 [Source:HGNC Symbol;Acc:HGNC:13107]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000147127	0.135	0	0	0	0	0	3	0	0	0	0	0	RAB41	"RAB41, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18293]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000147130	12.441	13.372	13.992	15.191	15.043	13.733	1415	1504.09	1149	1231	1419	1153	ZMYM3	zinc finger MYM-type containing 3 [Source:HGNC Symbol;Acc:HGNC:13054]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0007275//multicellular organism development;GO:0022604//regulation of cell morphogenesis	--
ENSG00000147133	5.38	4.578	4.251	3.8	4.44	3.581	801	697	490	425	533	413	TAF1	TATA-box binding protein associated factor 1 [Source:HGNC Symbol;Acc:HGNC:11535]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03125	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus;GO:0071339//MLL1 complex	GO:0000166//nucleotide binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0001181//RNA polymerase I general transcription initiation factor activity;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016922//nuclear receptor binding;GO:0017025//TBP-class protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0061628//H3K27me3 modified histone binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061631//ubiquitin conjugating enzyme activity;GO:0070577//lysine-acetylated histone binding;GO:0106310//protein serine kinase activity;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006352//DNA-templated transcription, initiation;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010629//negative regulation of gene expression;GO:0016310//phosphorylation;GO:0016573//histone acetylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030901//midbrain development;GO:0032092//positive regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034644//cellular response to UV;GO:0036369//transcription factor catabolic process;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0071318//cellular response to ATP;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1905524//negative regulation of protein autoubiquitination;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000825//positive regulation of androgen receptor activity"	--
ENSG00000147138	0.018	0	0	0	0	0.012	2	0	0	0	0	1	GPR174	G protein-coupled receptor 174 [Source:HGNC Symbol;Acc:HGNC:30245]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle	GO:0004930//G protein-coupled receptor activity;GO:0045125//bioactive lipid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043029//T cell homeostasis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000147140	113.729	117.128	116.698	108.162	107.397	114.281	6294	6472.91	4746	4425	4938	4544	NONO	non-POU domain containing octamer binding [Source:HGNC Symbol;Acc:HGNC:7871]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0042382//paraspeckles;GO:0090575//RNA polymerase II transcription regulator complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus;GO:0007623//circadian rhythm;GO:0008380//RNA splicing;GO:0042752//regulation of circadian rhythm;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:1903377//negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway"	--
ENSG00000147144	3.148	3.196	3.749	4.018	3.824	4.46	236	229	205	210	238	233	CCDC120	coiled-coil domain containing 120 [Source:HGNC Symbol;Acc:HGNC:28910]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding	GO:0008104//protein localization;GO:0034454//microtubule anchoring at centrosome	--
ENSG00000147145	0.789	0.695	0.454	0.508	0.512	0.908	55	47	31	24	37	50	LPAR4	lysophosphatidic acid receptor 4 [Source:HGNC Symbol;Acc:HGNC:4478]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Cell motility;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway	K04275;K04275;K04275;K04275;K04275;K04275;K04275	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	GO:0004930//G protein-coupled receptor activity;GO:0008289//lipid binding;GO:0035727//lysophosphatidic acid binding;GO:0070915//lysophosphatidic acid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000147155	14.892	14.198	18.961	16.705	16.497	18.082	347.51	333	326.77	288.74	325.23	307	EBP	EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K01824;K01824	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0110165//cellular anatomical entity	GO:0000247//C-8 sterol isomerase activity;GO:0004769//steroid delta-isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0047750//cholestenol delta-isomerase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0043931//ossification involved in bone maturation	--
ENSG00000147160	0	0	0	0	0	0	0	0	0	0	0	0	AWAT2	acyl-CoA wax alcohol acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:23251]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Metabolism of cofactors and vitamins;Digestive system	ko01100//Metabolic pathways;ko00830//Retinol metabolism;ko04977//Vitamin digestion and absorption	K11156;K11156;K11156	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047196//long-chain-alcohol O-fatty-acyltransferase activity;GO:0050252//retinol O-fatty-acyltransferase activity;GO:0102966//arachidoyl-CoA:1-dodecanol O-acyltransferase activity	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0010025//wax biosynthetic process;GO:0036155//acylglycerol acyl-chain remodeling;GO:0042572//retinol metabolic process;GO:0044255//cellular lipid metabolic process	--
ENSG00000147162	21.369	20.853	23.58	17.593	19.269	24.628	2270	2223	1895	1394	1707	1892	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase [Source:HGNC Symbol;Acc:HGNC:8127]	Human Diseases;Metabolism	Endocrine and metabolic disease;Glycan biosynthesis and metabolism	ko04931//Insulin resistance;ko00514//Other types of O-glycan biosynthesis	K09667;K09667	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016580//Sin3 complex;GO:0017122//protein N-acetylglucosaminyltransferase complex;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0044545//NSL complex	"GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016262//protein N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0097363//protein O-GlcNAc transferase activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000423//mitophagy;GO:0006110//regulation of glycolytic process;GO:0006111//regulation of gluconeogenesis;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007584//response to nutrient;GO:0016485//protein processing;GO:0030097//hemopoiesis;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0035020//regulation of Rac protein signal transduction;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045862//positive regulation of proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046626//regulation of insulin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048511//rhythmic process;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0060544//regulation of necroptotic process;GO:0061087//positive regulation of histone H3-K27 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900095//regulation of dosage compensation by inactivation of X chromosome;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000147164	37.495	34.309	36.488	39.193	43.61	36.145	1178	1085	897	926	1113	916	SNX12	sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17918	GO:0005769//early endosome;GO:0016020//membrane;GO:0030904//retromer complex;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding	GO:0010629//negative regulation of gene expression;GO:0010955//negative regulation of protein processing;GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0032456//endocytic recycling;GO:0034499//late endosome to Golgi transport;GO:0042177//negative regulation of protein catabolic process;GO:0051224//negative regulation of protein transport;GO:2000642//negative regulation of early endosome to late endosome transport	--
ENSG00000147166	0	0.075	0.045	0	0.089	0	0	2	1	0	2	0	ITGB1BP2	integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154]	-	-	-	-	GO:0030018//Z disc	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007517//muscle organ development	--
ENSG00000147168	0.456	0.259	0.97	0.308	0.501	0.41	14	8	22	7	13	7	IL2RG	interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune disease;Immune system;Signaling molecules and interaction;Immune system;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004911//interleukin-2 receptor activity;GO:0004913//interleukin-4 receptor activity;GO:0004917//interleukin-7 receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0019976//interleukin-2 binding;GO:0042010//interleukin-15 receptor activity	GO:0006955//immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0035723//interleukin-15-mediated signaling pathway;GO:0035771//interleukin-4-mediated signaling pathway;GO:0038110//interleukin-2-mediated signaling pathway;GO:0038111//interleukin-7-mediated signaling pathway;GO:0050766//positive regulation of phagocytosis	--
ENSG00000147174	0.105	0.26	0.331	0.047	0.021	0.096	6	15	14	2	1	4	GCNA	germ cell nuclear acidic peptidase [Source:HGNC Symbol;Acc:HGNC:15805]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body	GO:0005515//protein binding;GO:0032184//SUMO polymer binding	GO:0106300//protein-DNA covalent cross-linking repair	--
ENSG00000147180	5.763	4.042	4.268	3.096	3.925	4.125	483	350	257	201	278	255	ZNF711	zinc finger protein 711 [Source:HGNC Symbol;Acc:HGNC:13128]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000147183	0	0	0	0	0	0	0	0	0	0	0	0	CPXCR1	CPX chromosome region candidate 1 [Source:HGNC Symbol;Acc:HGNC:2332]	-	-	-	-	-	-	-	--
ENSG00000147202	3.937	3.018	2.895	1.801	2.475	2.986	569	365	278	194	313	306	DIAPH2	diaphanous related formin 2 [Source:HGNC Symbol;Acc:HGNC:2877]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05741	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0031267//small GTPase binding	GO:0007015//actin filament organization;GO:0007292//female gamete generation;GO:0016043//cellular component organization;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0048477//oogenesis	--
ENSG00000147206	0	0	0	0	0	0	0	0	0	0	0	0	NXF3	nuclear RNA export factor 3 [Source:HGNC Symbol;Acc:HGNC:8073]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14284;K14284;K14284;K14284;K14284;K14284	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0042272//nuclear RNA export factor complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000147223	0	0.122	0.055	0	0	0.253	0	2	1	0	0	3	RIPPLY1	ripply transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:25117]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001757//somite specification;GO:0009880//embryonic pattern specification;GO:0032525//somite rostral/caudal axis specification;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000147224	31.403	29.381	30.378	30.506	27.997	32.838	1113	1046	907	824	944	815	PRPS1	phosphoribosyl pyrophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:9462]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00948;K00948;K00948;K00948;K00948	GO:0002189//ribose phosphate diphosphokinase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0007399//nervous system development;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0034418//urate biosynthetic process;GO:0044249//cellular biosynthetic process;GO:0046101//hypoxanthine biosynthetic process	--
ENSG00000147231	1.615	1.482	1.309	1.077	1.273	1.503	126	117	74	62	84	72	RADX	"RPA1 related single stranded DNA binding protein, X-linked [Source:HGNC Symbol;Acc:HGNC:25486]"	-	-	-	-	GO:0005657//replication fork;GO:0005694//chromosome;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006282//regulation of DNA repair;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000147234	2.995	2.883	2.609	1.979	2.645	2.289	448	433	286	219	334	248	FRMPD3	FERM and PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29382]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030667//secretory granule membrane;GO:0070821//tertiary granule membrane	GO:0005515//protein binding	-	--
ENSG00000147246	0	0	0	0	0	0	0	0	0	0	0	0	HTR2C	5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system;Cellular community - eukaryotes	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04726//Serotonergic synapse;ko04750//Inflammatory mediator regulation of TRP channels;ko04540//Gap junction	K04157;K04157;K04157;K04157;K04157	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0098666//G protein-coupled serotonin receptor complex	"GO:0001587//Gq/11-coupled serotonin receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0042802//identical protein binding;GO:0051378//serotonin binding;GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding"	"GO:0001662//behavioral fear response;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007610//behavior;GO:0007626//locomotory behavior;GO:0007631//feeding behavior;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0019934//cGMP-mediated signaling;GO:0031644//regulation of nervous system process;GO:0032098//regulation of appetite;GO:0043397//regulation of corticotropin-releasing hormone secretion;GO:0045600//positive regulation of fat cell differentiation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000147251	0.594	0.278	0.488	0.137	0.272	0.335	78	39	47	14	32	32	DOCK11	dedicator of cytokinesis 11 [Source:HGNC Symbol;Acc:HGNC:23483]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0001782//B cell homeostasis;GO:0002315//marginal zone B cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051491//positive regulation of filopodium assembly	--
ENSG00000147255	3.392	3.421	4.441	2.364	2.768	3.552	221	212	187	108.04	161	172	IGSF1	immunoglobulin superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:5948]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0034711//inhibin binding;GO:0038102//activin receptor antagonist activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0032926//negative regulation of activin receptor signaling pathway"	--
ENSG00000147256	0.039	0	0.027	0	0	0	2	0	1	0	0	0	ARHGAP36	Rho GTPase activating protein 36 [Source:HGNC Symbol;Acc:HGNC:26388]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000147257	5.622	4.591	1.522	8.507	11.041	11.111	206	215	41	238	352	370	GPC3	glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K08109	GO:0005764//lysosome;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043202//lysosomal lumen;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0060422//peptidyl-dipeptidase inhibitor activity	"GO:0001523//retinoid metabolic process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0009966//regulation of signal transduction;GO:0010171//body morphogenesis;GO:0010466//negative regulation of peptidase activity;GO:0016477//cell migration;GO:0030282//bone mineralization;GO:0030316//osteoclast differentiation;GO:0030324//lung development;GO:0030513//positive regulation of BMP signaling pathway;GO:0035116//embryonic hindlimb morphogenesis;GO:0040008//regulation of growth;GO:0042074//cell migration involved in gastrulation;GO:0045732//positive regulation of protein catabolic process;GO:0045807//positive regulation of endocytosis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045926//negative regulation of growth;GO:0046326//positive regulation of glucose import;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060976//coronary vasculature development;GO:0072111//cell proliferation involved in kidney development;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0072180//mesonephric duct morphogenesis;GO:0072203//cell proliferation involved in metanephros development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1905475//regulation of protein localization to membrane;GO:2000050//regulation of non-canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000147262	0	0.011	0	0	0	0	0	1	0	0	0	0	GPR119	G protein-coupled receptor 119 [Source:HGNC Symbol;Acc:HGNC:19060]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04024//cAMP signaling pathway;ko04911//Insulin secretion	K08424;K08424	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0031210//phosphatidylcholine binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0030073//insulin secretion	--
ENSG00000147274	81.285	73.972	71.799	63.029	65.618	69.618	3661	3380.91	2374.84	2093	2470.9	2297.9	RBMX	RNA binding motif protein X-linked [Source:HGNC Symbol;Acc:HGNC:9910]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12885	GO:0000791//euchromatin;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0044530//supraspliceosomal complex;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0006366//transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0006509//membrane protein ectodomain proteolysis;GO:0008380//RNA splicing;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0051260//protein homooligomerization;GO:0071347//cellular response to interleukin-1"	--
ENSG00000147316	5.419	4.334	5.022	4.823	4.134	4.416	369	290	240	213	220	208	MCPH1	microcephalin 1 [Source:HGNC Symbol;Acc:HGNC:6954]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000132//establishment of mitotic spindle orientation;GO:0000278//mitotic cell cycle;GO:0010468//regulation of gene expression;GO:0021987//cerebral cortex development;GO:0043549//regulation of kinase activity;GO:0046605//regulation of centrosome cycle;GO:0050727//regulation of inflammatory response;GO:0060348//bone development;GO:0060623//regulation of chromosome condensation;GO:0071539//protein localization to centrosome;GO:0097150//neuronal stem cell population maintenance	--
ENSG00000147324	7.489	7.053	7.845	7.486	7.883	10.893	994	941	769	736	884	1052	MFHAS1	multifunctional ROCO family signaling regulator 1 [Source:HGNC Symbol;Acc:HGNC:16982]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031625//ubiquitin protein ligase binding;GO:0051721//protein phosphatase 2A binding	GO:0002376//immune system process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0009968//negative regulation of signal transduction;GO:0030218//erythrocyte differentiation;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0035308//negative regulation of protein dephosphorylation;GO:0043030//regulation of macrophage activation;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050728//negative regulation of inflammatory response;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900181//negative regulation of protein localization to nucleus;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000147364	6.331	6.516	6.406	7.324	6.523	8.363	759	777	560	621	657	635	FBXO25	F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596]	Environmental Information Processing	Signal transduction	ko04068//FoxO signaling pathway	K10305	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex	GO:0003779//actin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000147378	0	0	0	0	0	0	0	0	0	0	0	0	FATE1	fetal and adult testis expressed 1 [Source:HGNC Symbol;Acc:HGNC:24683]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0051562//negative regulation of mitochondrial calcium ion concentration	--
ENSG00000147381	0	0.07	0	0.095	0	0	0	1	0	1	0	0	MAGEA4	MAGE family member A4 [Source:HGNC Symbol;Acc:HGNC:6802]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0043066//negative regulation of apoptotic process;GO:0045787//positive regulation of cell cycle	--
ENSG00000147383	13.212	12.703	12.833	16.138	14.172	17.981	460	446	329	404	416	456	NSDHL	NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K07748;K07748	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000252//C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity;GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047012//sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity;GO:0102175//3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity;GO:0103066//4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity;GO:0103067//4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity"	GO:0001942//hair follicle development;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0007224//smoothened signaling pathway;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0060716//labyrinthine layer blood vessel development	--
ENSG00000147394	13.952	16.167	12.53	13.886	12.872	12.302	1189	1403	775	860	929	757	ZNF185	zinc finger protein 185 with LIM domain [Source:HGNC Symbol;Acc:HGNC:12976]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030054//cell junction	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	-	--
ENSG00000147400	40.773	39.139	38.806	32.842	30.006	31.043	1195	1153	840	713	743	662	CETN2	centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867]	Genetic Information Processing	Replication and repair	ko03420//Nucleotide excision repair	K10840	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0044615//nuclear pore nuclear basket;GO:0045177//apical part of cell;GO:0070390//transcription export complex 2;GO:0071942//XPC complex;GO:0097729//9+2 motile cilium	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0032795//heterotrimeric G-protein binding;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0007283//spermatogenesis;GO:0015031//protein transport;GO:0032465//regulation of cytokinesis;GO:0051028//mRNA transport;GO:0051301//cell division	--
ENSG00000147403	844.906	905.11	903.12	1102.334	927.961	814.235	11965.74	12951.44	9381.76	11525.48	11147.61	8353.03	RPL10	ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02866;K02866	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005790//smooth endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0032991//protein-containing complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045182//translation regulator activity	GO:0000027//ribosomal large subunit assembly;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006417//regulation of translation;GO:0043066//negative regulation of apoptotic process;GO:1990403//embryonic brain development	--
ENSG00000147408	0.091	0.212	0.071	0.07	0.17	0.033	7	16	4	4	11	1	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24290]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00746;K00746	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008955//peptidoglycan glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	"GO:0001958//endochondral ossification;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0030198//extracellular matrix organization;GO:0030204//chondroitin sulfate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030210//heparin biosynthetic process;GO:0046398//UDP-glucuronate metabolic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0050653//chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0051216//cartilage development"	--
ENSG00000147416	48.322	49.968	48.571	47.595	45.306	50.521	2858	2966	2116	2084	2242	2151	ATP6V1B2	ATPase H+ transporting V1 subunit B2 [Source:HGNC Symbol;Acc:HGNC:854]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147;K02147	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015078//proton transmembrane transporter activity;GO:0016787//hydrolase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006996//organelle organization;GO:0016241//regulation of macroautophagy;GO:0046034//ATP metabolic process;GO:1902600//proton transmembrane transport	--
ENSG00000147419	10.916	10.185	9.814	7.82	7.383	8.417	683	688	474	415	423	402	CCDC25	coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding	GO:2000147//positive regulation of cell motility	--
ENSG00000147421	7.014	5.163	5.555	4.086	5.057	5.786	256	229	169	113	169	164	HMBOX1	homeobox containing 1 [Source:HGNC Symbol;Acc:HGNC:26137]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0016605//PML body"	GO:0003677//DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0031328//positive regulation of cellular biosynthetic process;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035563//positive regulation of chromatin binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045935//positive regulation of nucleobase-containing compound metabolic process;GO:0051972//regulation of telomerase activity;GO:0051973//positive regulation of telomerase activity"	Homeobox
ENSG00000147432	0.041	0.061	0	0	0.024	0.028	2	3	0	0	1	1	CHRNB3	cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04814	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098691//dopaminergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0015267//channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:1901363//heterocyclic compound binding	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000147434	0	0	0	0	0	0	0	0	0	0	0	0	CHRNA6	cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963]	Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04725//Cholinergic synapse;ko05033//Nicotine addiction	K04808;K04808;K04808	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098691//dopaminergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0014059//regulation of dopamine secretion;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051899//membrane depolarization;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000147437	0.164	0.164	0.074	0.495	0.227	0.113	6	6	2	7	7	3	GNRH1	gonadotropin releasing hormone 1 [Source:HGNC Symbol;Acc:HGNC:4419]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04912//GnRH signaling pathway;ko04929//GnRH secretion	K05252;K05252;K05252	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005183//gonadotropin hormone-releasing hormone activity;GO:0031530//gonadotropin-releasing hormone receptor binding	GO:0000003//reproduction;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0010468//regulation of gene expression;GO:0045471//response to ethanol;GO:0048545//response to steroid hormone;GO:2000354//regulation of ovarian follicle development;GO:2001223//negative regulation of neuron migration	--
ENSG00000147439	6.381	7.493	7.029	5.348	5.719	7.05	229	268	169	147	184	188	BIN3	bridging integrator 3 [Source:HGNC Symbol;Acc:HGNC:1054]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton	GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0008289//lipid binding	GO:0000917//division septum assembly;GO:0006897//endocytosis;GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0008104//protein localization;GO:0009826//unidimensional cell growth;GO:0010591//regulation of lamellipodium assembly;GO:0014839//myoblast migration involved in skeletal muscle regeneration;GO:0043403//skeletal muscle tissue regeneration;GO:0048741//skeletal muscle fiber development;GO:0051301//cell division;GO:0051666//actin cortical patch localization;GO:0061640//cytoskeleton-dependent cytokinesis;GO:0097320//plasma membrane tubulation	--
ENSG00000147443	0	0	0	0	0.032	0	0	0	0	0	1	0	DOK2	docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K20234	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction	--
ENSG00000147454	3.27	3.757	3.253	4.666	3.422	3.715	271	288	188	258	230	214	SLC25A37	solute carrier family 25 member 37 [Source:HGNC Symbol;Acc:HGNC:29786]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005381//iron ion transmembrane transporter activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048250//iron import into the mitochondrion;GO:0055072//iron ion homeostasis	--
ENSG00000147457	17.438	17.021	17.266	15.457	16.298	17.258	944	1024	742	676	800	748	CHMP7	charged multivesicular body protein 7 [Source:HGNC Symbol;Acc:HGNC:28439]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K15053;K15053	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000815//ESCRT III complex;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0032585//multivesicular body membrane;GO:1904930//amphisome membrane	GO:0005515//protein binding	GO:0001778//plasma membrane repair;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0010458//exit from mitosis;GO:0015031//protein transport;GO:0031468//nuclear membrane reassembly;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071168//protein localization to chromatin;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904903//ESCRT III complex disassembly	--
ENSG00000147459	3.063	2.735	2.833	1.962	2.662	2.651	649	574	423	304	476	408	DOCK5	dedicator of cytokinesis 5 [Source:HGNC Symbol;Acc:HGNC:23476]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007264//small GTPase mediated signal transduction;GO:0010634//positive regulation of epithelial cell migration;GO:0016477//cell migration;GO:0050790//regulation of catalytic activity;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1904694//negative regulation of vascular associated smooth muscle contraction;GO:1904754//positive regulation of vascular associated smooth muscle cell migration	--
ENSG00000147465	0.132	0	0.025	0.076	0	0.026	7	0	1	3	0	1	STAR	steroidogenic acute regulatory protein [Source:HGNC Symbol;Acc:HGNC:11359]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Digestive system	ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion;ko04913//Ovarian steroidogenesis;ko04979//Cholesterol metabolism	K16931;K16931;K16931;K16931;K16931	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0120020//cholesterol transfer activity	GO:0006694//steroid biosynthetic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008211//glucocorticoid metabolic process;GO:0015918//sterol transport;GO:0032367//intracellular cholesterol transport;GO:0044255//cellular lipid metabolic process;GO:0050810//regulation of steroid biosynthetic process;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0120009//intermembrane lipid transfer	--
ENSG00000147471	40.554	38.183	37.435	36.202	37.239	36.967	1312	1299	1010	935	1092	859	PLPBP	pyridoxal phosphate binding protein [Source:HGNC Symbol;Acc:HGNC:9457]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0030170//pyridoxal phosphate binding	GO:0008150//biological_process	--
ENSG00000147475	29.203	26.489	26.224	24.455	24.201	25.101	2602	2606	2010	1840	2096	1593	ERLIN2	ER lipid raft associated 2 [Source:HGNC Symbol;Acc:HGNC:1356]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0031625//ubiquitin protein ligase binding	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032933//SREBP signaling pathway;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0045717//negative regulation of fatty acid biosynthetic process	--
ENSG00000147481	0	0.069	0	0	0	0	0	3	0	0	0	0	SNTG1	syntrophin gamma 1 [Source:HGNC Symbol;Acc:HGNC:13740]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016013//syntrophin complex;GO:0032587//ruffle membrane	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0007154//cell communication	--
ENSG00000147485	1.675	1.926	1.331	3.062	3.097	2.619	167	193	98	223	252	190	PXDNL	peroxidasin like [Source:HGNC Symbol;Acc:HGNC:26359]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0006979//response to oxidative stress;GO:0042744//hydrogen peroxide catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0098869//cellular oxidant detoxification	--
ENSG00000147488	0	0	0.025	0	0	0	0	0	1	0	0	0	ST18	ST18 C2H2C-type zinc finger transcription factor [Source:HGNC Symbol;Acc:HGNC:18695]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0032993//protein-DNA complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"	zf-C2HC
ENSG00000147509	0.101	0.136	0	0	0.04	0	3	6	0	0	1	0	RGS20	regulator of G protein signaling 20 [Source:HGNC Symbol;Acc:HGNC:14600]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000147526	128.755	117.489	110.145	94.381	104.207	102.034	14151	12646	8976	7682	9833	8032	TACC1	transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030496//midbody	GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0035259//glucocorticoid receptor binding;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0046965//retinoid X receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0008283//cell population proliferation;GO:0021987//cerebral cortex development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division"	--
ENSG00000147533	41.522	39.094	40.168	40.639	41.152	45.399	1272	1206	935	889	1090	1052	GOLGA7	golgin A7 [Source:HGNC Symbol;Acc:HGNC:24876]	-	-	-	-	GO:0000139//Golgi membrane;GO:0002178//palmitoyltransferase complex;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0005515//protein binding	GO:0006612//protein targeting to membrane;GO:0006893//Golgi to plasma membrane transport;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0043001//Golgi to plasma membrane protein transport;GO:0050821//protein stabilization	--
ENSG00000147535	18.917	16.66	19.679	16.426	13.506	13.929	609	508	422	337	366	297	PLPP5	phospholipid phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:25026]	Metabolism;Metabolism	Lipid metabolism;Lipid metabolism	ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K18693;K18693	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000810//diacylglycerol diphosphate phosphatase activity;GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0046839//phospholipid dephosphorylation	--
ENSG00000147536	1.855	1.886	1.493	0.95	0.863	0.738	106	124	82	55	57	42	GINS4	GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226]	-	-	-	-	GO:0000811//GINS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0071162//CMG complex	GO:0005515//protein binding	GO:0000727//double-strand break repair via break-induced replication;GO:0001833//inner cell mass cell proliferation;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:1900264//positive regulation of DNA-directed DNA polymerase activity;GO:1903934//positive regulation of DNA primase activity	--
ENSG00000147548	25.369	19.833	18.26	12.886	13.615	17.64	2397	1840	1377	954	1215	1172	NSD3	nuclear receptor binding SET domain protein 3 [Source:HGNC Symbol;Acc:HGNC:12767]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11425;K11425	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0140537//transcription regulator activator activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0010452//histone H3-K36 methylation;GO:0016571//histone methylation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:2001255//positive regulation of histone H3-K36 trimethylation"	--
ENSG00000147570	0	0	0	0	0	0	0	0	0	0	0	0	DNAJC5B	DnaJ heat shock protein family (Hsp40) member C5 beta [Source:HGNC Symbol;Acc:HGNC:24138]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09525	GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000147571	0	0	0	0	0	0	0	0	0	0	0	0	CRH	corticotropin releasing hormone [Source:HGNC Symbol;Acc:HGNC:2355]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Substance dependence;Endocrine and metabolic disease;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04934//Cushing syndrome;ko04730//Long-term depression	K05256;K05256;K05256;K05256;K05256	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0017045//corticotropin-releasing hormone activity	"GO:0001963//synaptic transmission, dopaminergic;GO:0006704//glucocorticoid biosynthetic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007565//female pregnancy;GO:0007567//parturition;GO:0007611//learning or memory;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0030324//lung development;GO:0030325//adrenal gland development;GO:0032811//negative regulation of epinephrine secretion;GO:0035641//locomotory exploration behavior;GO:0042322//negative regulation of circadian sleep/wake cycle, REM sleep;GO:0051461//positive regulation of corticotropin secretion;GO:0051464//positive regulation of cortisol secretion;GO:0070093//negative regulation of glucagon secretion;GO:2000310//regulation of NMDA receptor activity"	--
ENSG00000147573	0.037	0	0	0.055	0	0	2	0	0	1	0	0	TRIM55	tripartite motif containing 55 [Source:HGNC Symbol;Acc:HGNC:14215]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002523//leukocyte migration involved in inflammatory response;GO:0007165//signal transduction;GO:0016567//protein ubiquitination;GO:0050904//diapedesis;GO:1905517//macrophage migration	--
ENSG00000147576	1.004	0.839	1.766	2.267	2.578	1.83	43.55	31.49	51.28	70.13	73.37	51.96	ADHFE1	alcohol dehydrogenase iron containing 1 [Source:HGNC Symbol;Acc:HGNC:16354]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0047988//hydroxyacid-oxoacid transhydrogenase activity	GO:0006103//2-oxoglutarate metabolic process;GO:0006539//glutamate catabolic process via 2-oxoglutarate;GO:0006629//lipid metabolic process	--
ENSG00000147586	13.627	11.914	16.359	14.853	14.719	13.797	184.91	180.26	182	161.97	166.98	158	MRPS28	mitochondrial ribosomal protein S28 [Source:HGNC Symbol;Acc:HGNC:14513]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding	GO:0032543//mitochondrial translation	--
ENSG00000147588	0	0.027	0.074	0	0.045	0.06	0	2	4	0	1	2	PMP2	peripheral myelin protein 2 [Source:HGNC Symbol;Acc:HGNC:9117]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0070062//extracellular exosome	GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding	GO:0015908//fatty acid transport;GO:0061024//membrane organization	--
ENSG00000147592	10.077	7.931	7.096	6.869	7.134	8.327	248	189	130	117	139	142	LACTB2	lactamase beta 2 [Source:HGNC Symbol;Acc:HGNC:18512]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000147596	0	0	0	0	0	0	0	0	0	0	0	0	PRDM14	PR/SET domain 14 [Source:HGNC Symbol;Acc:HGNC:14001]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0031490//chromatin DNA binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001708//cell fate specification;GO:0001827//inner cell mass cell fate commitment;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007566//embryo implantation;GO:0009566//fertilization;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0030718//germ-line stem cell population maintenance;GO:0032259//methylation;GO:0034972//histone H3-R26 methylation;GO:0040029//regulation of gene expression, epigenetic;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0044030//regulation of DNA methylation;GO:0048873//homeostasis of number of cells within a tissue;GO:0060817//inactivation of paternal X chromosome;GO:1902093//positive regulation of flagellated sperm motility;GO:1902459//positive regulation of stem cell population maintenance"	zf-C2H2
ENSG00000147601	10.01	8.922	8.365	7.175	7.005	7.935	660	602	414	347	400	353	TERF1	telomeric repeat binding factor 1 [Source:HGNC Symbol;Acc:HGNC:11728]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0043229//intracellular organelle;GO:0070187//shelterin complex"	"GO:0003677//DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003720//telomerase activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0008301//DNA binding, bending;GO:0042162//telomeric DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0071532//ankyrin repeat binding;GO:0098505//G-rich strand telomeric DNA binding"	GO:0000723//telomere maintenance;GO:0007004//telomere maintenance via telomerase;GO:0007049//cell cycle;GO:0008156//negative regulation of DNA replication;GO:0009410//response to xenobiotic stimulus;GO:0016233//telomere capping;GO:0032206//positive regulation of telomere maintenance;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032214//negative regulation of telomere maintenance via semi-conservative replication;GO:0045141//meiotic telomere clustering;GO:0051301//cell division;GO:0051974//negative regulation of telomerase activity;GO:0061820//telomeric D-loop disassembly;GO:0090656//t-circle formation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904792//positive regulation of shelterin complex assembly;GO:1904850//negative regulation of establishment of protein localization to telomere;GO:1904911//negative regulation of establishment of RNA localization to telomere;GO:1904914//negative regulation of establishment of protein-containing complex localization to telomere;GO:1905778//negative regulation of exonuclease activity;GO:1905839//negative regulation of telomeric D-loop disassembly	MYB
ENSG00000147604	649	674.961	601.021	602.501	541.845	486.543	11905	12360	8161	8296	8394	6558	RPL7	ribosomal protein L7 [Source:HGNC Symbol;Acc:HGNC:10363]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02937;K02937	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042273//ribosomal large subunit biogenesis"	--
ENSG00000147606	7.827	5.994	5.136	2.249	3.074	3.94	836	623	407	181	275	275	SLC26A7	solute carrier family 26 member 7 [Source:HGNC Symbol;Acc:HGNC:14467]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K13962	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0055038//recycling endosome membrane	GO:0005253//anion channel activity;GO:0005254//chloride channel activity;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0001696//gastric acid secretion;GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000147613	0	0	0	0	0	0	0	0	0	0	0	0	PSKH2	protein serine kinase H2 [Source:HGNC Symbol;Acc:HGNC:18997]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000147614	0	0.02	0	0.027	0.024	0.056	0	1	0	1	1	2	ATP6V0D2	ATPase H+ transporting V0 subunit d2 [Source:HGNC Symbol;Acc:HGNC:18266]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Cancer: overview;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05203//Viral carcinogenesis;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146	"GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030670//phagocytic vesicle membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0033181//plasma membrane proton-transporting V-type ATPase complex;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0016241//regulation of macroautophagy;GO:1902600//proton transmembrane transport	--
ENSG00000147642	2.593	3.823	2.698	6.415	4.05	5.306	123	148	112	184	160	160	SYBU	syntabulin [Source:HGNC Symbol;Acc:HGNC:26011]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019894//kinesin binding	GO:0019896//axonal transport of mitochondrion;GO:0060074//synapse maturation	--
ENSG00000147647	0.023	0.045	0.031	0	0.081	0.031	1	2	1	0	3	1	DPYS	dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism;Metabolism of other amino acids;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism;ko00410//beta-Alanine metabolism;ko00770//Pantothenate and CoA biosynthesis	K01464;K01464;K01464;K01464;K01464	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004157//dihydropyrimidinase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding"	GO:0006208//pyrimidine nucleobase catabolic process;GO:0006210//thymine catabolic process;GO:0006212//uracil catabolic process;GO:0006248//CMP catabolic process;GO:0006249//dCMP catabolic process;GO:0046050//UMP catabolic process;GO:0046079//dUMP catabolic process	--
ENSG00000147649	29.565	25.301	24.562	17.407	20.316	21.111	2444	2084	1472	950	1373	1345	MTDH	metadherin [Source:HGNC Symbol;Acc:HGNC:29608]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0046581//intercellular canaliculus;GO:0048471//perinuclear region of cytoplasm	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0051059//NF-kappaB binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010508//positive regulation of autophagy;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling"	--
ENSG00000147650	7.307	6.795	7.066	5.928	4.97	5.998	604	591	405	315	365	379	LRP12	LDL receptor related protein 12 [Source:HGNC Symbol;Acc:HGNC:31708]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0040008//regulation of growth	--
ENSG00000147654	11.447	13.593	11.064	11.937	9.618	11.691	313	332	210	232	233	250	EBAG9	estrogen receptor binding site associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:3123]	Organismal Systems	Endocrine system	ko04915//Estrogen signaling pathway	K22455	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule	GO:0005515//protein binding;GO:0016505//peptidase activator activity involved in apoptotic process	GO:0001558//regulation of cell growth;GO:0006915//apoptotic process	--
ENSG00000147655	0.194	0.307	0.106	0.501	0.644	0.36	10	17	5	20	21	16	RSPO2	R-spondin 2 [Source:HGNC Symbol;Acc:HGNC:28583]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K23097	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0001649//osteoblast differentiation;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030282//bone mineralization;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0042489//negative regulation of odontogenesis of dentin-containing tooth;GO:0050896//response to stimulus;GO:0060173//limb development;GO:0060437//lung growth;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060535//trachea cartilage morphogenesis;GO:0071542//dopaminergic neuron differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000147669	22.095	24.808	23.092	19.588	18.172	22.27	434	487	335	285	299	317	POLR2K	"RNA polymerase II, I and III subunit K [Source:HGNC Symbol;Acc:HGNC:9198]"	Human Diseases;Organismal Systems;Genetic Information Processing	Neurodegenerative disease;Immune system;Transcription	ko05016//Huntington disease;ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03009;K03009;K03009	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006356//regulation of transcription by RNA polymerase I;GO:0006366//transcription by RNA polymerase II;GO:0006383//transcription by RNA polymerase III"	--
ENSG00000147676	27.312	24.899	20.72	28.743	33.005	34.162	1596	1467	897	1248	1630	1457	MAL2	"mal, T cell differentiation protein 2 [Source:HGNC Symbol;Acc:HGNC:13634]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath	GO:0042552//myelination;GO:0045056//transcytosis	--
ENSG00000147677	72.036	72.765	70.053	66.26	66.674	63.975	3482	3361	2391	2206	2620	2251	EIF3H	eukaryotic translation initiation factor 3 subunit H [Source:HGNC Symbol;Acc:HGNC:3273]	Human Diseases	Infectious disease: viral	ko05162//Measles	K03247	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008237//metallopeptidase activity;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0006508//proteolysis;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000147679	7.151	5.287	5.038	5.467	5.553	5.761	416	286	238	230	256	186	UTP23	UTP23 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:28224]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding;GO:0070181//small ribosomal subunit rRNA binding	"GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis"	--
ENSG00000147684	64.349	60.139	69.887	77.179	59.249	70.775	936	888	750.25	834	726	750	NDUFB9	NADH:ubiquinone oxidoreductase subunit B9 [Source:HGNC Symbol;Acc:HGNC:7704]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965;K03965	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007605//sensory perception of sound;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000147687	8.466	7.551	6.751	4.365	5.839	6.298	153	140	94	66	89	81	TATDN1	TatD DNase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24220]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0006259//DNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000147689	0.037	0.037	0.036	0.045	0.213	0.153	3	3	3	2	16	9	FAM83A	family with sequence similarity 83 member A [Source:HGNC Symbol;Acc:HGNC:28210]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008283//cell population proliferation	--
ENSG00000147697	0	0	0	0	0	0	0	0	0	0	0	0	GSDMC	gasdermin C [Source:HGNC Symbol;Acc:HGNC:7151]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001786//phosphatidylserine binding;GO:0003674//molecular_function;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding"	GO:0008150//biological_process;GO:0012501//programmed cell death;GO:0042742//defense response to bacterium;GO:0070269//pyroptosis	--
ENSG00000147724	0.612	0.425	0.716	0.352	0.37	0.519	94	61	63	40	43	58	FAM135B	family with sequence similarity 135 member B [Source:HGNC Symbol;Acc:HGNC:28029]	-	-	-	-	-	-	GO:0044255//cellular lipid metabolic process	--
ENSG00000147789	4.917	5.673	5.324	5.539	4.74	4.951	234.72	271	192.73	180.41	201.98	168.21	ZNF7	zinc finger protein 7 [Source:HGNC Symbol;Acc:HGNC:13139]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development"	zf-C2H2
ENSG00000147799	3.097	3.148	3.095	2.738	3.078	2.623	310	317	229	203	259	191	ARHGAP39	Rho GTPase activating protein 39 [Source:HGNC Symbol;Acc:HGNC:29351]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0098978//glutamatergic synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0099173//postsynapse organization	--
ENSG00000147804	0.068	0.023	0.031	0.184	0.108	0.094	3	1	1	6	4	3	SLC39A4	solute carrier family 39 member 4 [Source:HGNC Symbol;Acc:HGNC:17129]	Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Digestive system	ko05010//Alzheimer disease;ko05012//Parkinson disease;ko04978//Mineral absorption	K14710;K14710;K14710	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0055038//recycling endosome membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0034224//cellular response to zinc ion starvation;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071578//zinc ion import across plasma membrane	--
ENSG00000147813	12	14.074	16.126	15.067	14.814	19.347	421	497	425	392	443	495	NAPRT	nicotinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30450]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00763;K00763	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0004516//nicotinate phosphoribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006979//response to oxidative stress;GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process;GO:0034355//NAD salvage	--
ENSG00000147852	25.778	25.384	24.583	19.943	21.415	26.029	1954	1970	1378	1096	1304	1375	VLDLR	very low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:12698]	Human Diseases;Human Diseases	Cardiovascular disease;Neurodegenerative disease	ko05417//Lipid and atherosclerosis;ko05017//Spinocerebellar ataxia	K20053;K20053	GO:0005615//extracellular space;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034361//very-low-density lipoprotein particle;GO:0043235//receptor complex	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0034185//apolipoprotein binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0038024//cargo receptor activity;GO:0038025//reelin receptor activity;GO:0048306//calcium-dependent protein binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007613//memory;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0021517//ventral spinal cord development;GO:0034436//glycoprotein transport;GO:0034447//very-low-density lipoprotein particle clearance;GO:0038026//reelin-mediated signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0048813//dendrite morphogenesis;GO:1900006//positive regulation of dendrite development	--
ENSG00000147853	50.025	45.25	47.647	46.513	46.449	53.929	2789	2383	1924	1868	2029	2085	AK3	adenylate kinase 3 [Source:HGNC Symbol;Acc:HGNC:17376]	Metabolism	Nucleotide metabolism	ko00230//Purine metabolism	K00944	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0046899//nucleoside triphosphate adenylate kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006172//ADP biosynthetic process;GO:0007596//blood coagulation;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0046033//AMP metabolic process;GO:0046039//GTP metabolic process;GO:0046041//ITP metabolic process;GO:0046051//UTP metabolic process	--
ENSG00000147854	11.297	10.316	11.72	7.623	8.262	11.311	805	737	565	406	519	550	UHRF2	ubiquitin like with PHD and ring finger domains 2 [Source:HGNC Symbol;Acc:HGNC:12557]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061630//ubiquitin protein ligase activity	GO:0007049//cell cycle;GO:0010216//maintenance of DNA methylation;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0030154//cell differentiation;GO:0051726//regulation of cell cycle;GO:0051865//protein autoubiquitination	--
ENSG00000147862	7.779	5.19	4.524	2.593	3.207	4.261	873	714	482	279	384	388	NFIB	nuclear factor I B [Source:HGNC Symbol;Acc:HGNC:7785]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0044300//cerebellar mossy fiber	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002062//chondrocyte differentiation;GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0010001//glial cell differentiation;GO:0021740//principal sensory nucleus of trigeminal nerve development;GO:0021960//anterior commissure morphogenesis;GO:0030324//lung development;GO:0030900//forebrain development;GO:0030902//hindbrain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060486//club cell differentiation;GO:0060509//type I pneumocyte differentiation;GO:0060510//type II pneumocyte differentiation;GO:0060662//salivary gland cavitation;GO:0060689//cell differentiation involved in salivary gland development;GO:0061141//lung ciliated cell differentiation;GO:0071679//commissural neuron axon guidance;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:2000791//negative regulation of mesenchymal cell proliferation involved in lung development;GO:2000795//negative regulation of epithelial cell proliferation involved in lung morphogenesis"	CTF/NFI
ENSG00000147869	0	0	0	0	0	0	0	0	0	0	0	0	CER1	"cerberus 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:1862]"	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K01645	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0016015//morphogen activity;GO:0036122//BMP binding;GO:0042803//protein homodimerization activity	GO:0001657//ureteric bud development;GO:0003419//growth plate cartilage chondrocyte proliferation;GO:0007369//gastrulation;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030282//bone mineralization;GO:0030514//negative regulation of BMP signaling pathway;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0035582//sequestering of BMP in extracellular matrix;GO:0042074//cell migration involved in gastrulation;GO:0048263//determination of dorsal identity;GO:0061371//determination of heart left/right asymmetry;GO:0071276//cellular response to cadmium ion;GO:0071773//cellular response to BMP stimulus;GO:1900176//negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:2000381//negative regulation of mesoderm development	--
ENSG00000147872	49.151	46.974	50.657	53.063	50.684	50.485	1894	1832	1461	1530	1676	1427	PLIN2	perilipin 2 [Source:HGNC Symbol;Acc:HGNC:248]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K17284	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0009410//response to xenobiotic stimulus;GO:0010890//positive regulation of sequestering of triglyceride;GO:0014070//response to organic cyclic compound;GO:0015909//long-chain fatty acid transport;GO:0019915//lipid storage;GO:0042149//cellular response to glucose starvation;GO:1905691//lipid droplet disassembly	--
ENSG00000147873	0	0	0	0	0	0	0	0	0	0	0	0	IFNA5	interferon alpha 5 [Source:HGNC Symbol;Acc:HGNC:5426]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000147874	3.412	2.646	2.221	1.575	2.468	2.148	438	316	213	153	196	205	HAUS6	HAUS augmin like complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:25948]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000147883	19.304	18.16	8.706	9.151	12.352	12.002	1526	1451	492	529	834	692	CDKN2B	cyclin dependent kinase inhibitor 2B [Source:HGNC Symbol;Acc:HGNC:1788]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases	Cancer: overview;Infectious disease: viral;Cancer: overview;Cell growth and death;Endocrine and metabolic disease;Cancer: specific types;Signal transduction;Cell growth and death;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko05226//Gastric cancer;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway;ko05222//Small cell lung cancer	K04685;K04685;K04685;K04685;K04685;K04685;K04685;K04685;K04685;K04685	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001889//liver development;GO:0007049//cell cycle;GO:0007568//aging;GO:0008285//negative regulation of cell population proliferation;GO:0014070//response to organic cyclic compound;GO:0016310//phosphorylation;GO:0030219//megakaryocyte differentiation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030858//positive regulation of epithelial cell differentiation;GO:0031668//cellular response to extracellular stimulus;GO:0031670//cellular response to nutrient;GO:0034097//response to cytokine;GO:0042326//negative regulation of phosphorylation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0048536//spleen development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060253//negative regulation of glial cell proliferation;GO:0070316//regulation of G0 to G1 transition;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090398//cellular senescence;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000147885	0	0	0	0	0	0	0	0	0	0	0	0	IFNA16	interferon alpha 16 [Source:HGNC Symbol;Acc:HGNC:5421]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000147889	15.737	17.439	13.929	13.41	12.859	12.81	323	351	214	203	219	183	CDKN2A	cyclin dependent kinase inhibitor 2A [Source:HGNC Symbol;Acc:HGNC:1787]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: specific types;Cell growth and death;Endocrine and metabolic disease;Cell growth and death;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko04110//Cell cycle;ko01522//Endocrine resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05219//Bladder cancer	K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621;K06621	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032991//protein-containing complex;GO:0035985//senescence-associated heterochromatin focus	GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019789//SUMO transferase activity;GO:0019901//protein kinase binding;GO:0051059//NF-kappaB binding;GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0097718//disordered domain specific binding;GO:1990948//ubiquitin ligase inhibitor activity	"GO:0000209//protein polyubiquitination;GO:0001953//negative regulation of cell-matrix adhesion;GO:0006364//rRNA processing;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0008637//apoptotic mitochondrial changes;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0016925//protein sumoylation;GO:0030308//negative regulation of cell growth;GO:0030889//negative regulation of B cell proliferation;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0033235//positive regulation of protein sumoylation;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0042326//negative regulation of phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046825//regulation of protein export from nucleus;GO:0048103//somatic stem cell division;GO:0050821//protein stabilization;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051726//regulation of cell cycle;GO:0070534//protein K63-linked ubiquitination;GO:0090398//cellular senescence;GO:0090399//replicative senescence;GO:1900182//positive regulation of protein localization to nucleus;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:1902510//regulation of apoptotic DNA fragmentation;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:1990000//amyloid fibril formation;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2000111//positive regulation of macrophage apoptotic process;GO:2000435//negative regulation of protein neddylation"	--
ENSG00000147894	4.511	3.455	2.877	2.695	3.941	5.275	212	182	106	123	177	170	C9orf72	C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04140//Autophagy - animal	K23609;K23609;K23609	GO:0000932//P-body;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0044295//axonal growth cone;GO:0044304//main axon;GO:0090543//Flemming body;GO:0098793//presynapse;GO:0098794//postsynapse;GO:1990316//Atg1/ULK1 kinase complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0016239//positive regulation of macroautophagy;GO:0032880//regulation of protein localization;GO:0034063//stress granule assembly;GO:0043547//positive regulation of GTPase activity;GO:0045920//negative regulation of exocytosis;GO:0048675//axon extension;GO:0050777//negative regulation of immune response;GO:0050790//regulation of catalytic activity;GO:0110053//regulation of actin filament organization;GO:1902774//late endosome to lysosome transport;GO:1903432//regulation of TORC1 signaling;GO:1904425//negative regulation of GTP binding;GO:2000785//regulation of autophagosome assembly	--
ENSG00000147896	0	0	0	0	0	0	0	0	0	0	0	0	IFNK	interferon kappa [Source:HGNC Symbol;Acc:HGNC:21714]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04622//RIG-I-like receptor signaling pathway	K05441;K05441;K05441	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	"GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030101//natural killer cell activation;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus"	--
ENSG00000147905	7.328	6.846	5.969	3.762	4.779	4.77	395	367	234	150	216	186	ZCCHC7	zinc finger CCHC-type containing 7 [Source:HGNC Symbol;Acc:HGNC:26209]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12597	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000147912	12.339	11.598	12.575	13.147	15.139	14.455	1131.7	1136	905	947.61	1170	1025	FBXO10	F-box protein 10 [Source:HGNC Symbol;Acc:HGNC:13589]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000147955	49.656	54.017	53.366	64.207	62.557	58.294	1697	1830	1312	1607	1752	1452	SIGMAR1	sigma non-opioid intracellular receptor 1 [Source:HGNC Symbol;Acc:HGNC:8157]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K20719;K20719	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane	GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0006869//lipid transport;GO:0007399//nervous system development;GO:0036474//cell death in response to hydrogen peroxide;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0043523//regulation of neuron apoptotic process;GO:0070207//protein homotrimerization	--
ENSG00000147996	7.313	6.89	8.251	6.303	7.42	8.092	201.61	206.55	185.69	130.07	186.92	175.26	CBWD5	COBW domain containing 5 [Source:HGNC Symbol;Acc:HGNC:24584]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000148019	6.531	5.086	5.734	3.694	4.28	3.49	587	430	317	217	311	226	CEP78	centrosomal protein 78 [Source:HGNC Symbol;Acc:HGNC:25740]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0044782//cilium organization	--
ENSG00000148053	1.367	1.312	1.415	2.396	2.036	2.252	206	186	150	261	256	223	NTRK2	neurotrophic receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:8032]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Substance dependence;Nervous system	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05034//Alcoholism;ko04722//Neurotrophin signaling pathway	K04360;K04360;K04360;K04360;K04360;K04360	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0043679//axon terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005030//neurotrophin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0043121//neurotrophin binding;GO:0048403//brain-derived neurotrophic factor binding;GO:0060175//brain-derived neurotrophic factor-activated receptor activity	"GO:0001570//vasculogenesis;GO:0001764//neuron migration;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007612//learning;GO:0007623//circadian rhythm;GO:0007631//feeding behavior;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0014047//glutamate secretion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019222//regulation of metabolic process;GO:0019227//neuronal action potential propagation;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0022011//myelination in peripheral nervous system;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0038179//neurotrophin signaling pathway;GO:0042490//mechanoreceptor differentiation;GO:0043087//regulation of GTPase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0046548//retinal rod cell development;GO:0046777//protein autophosphorylation;GO:0048709//oligodendrocyte differentiation;GO:0048935//peripheral nervous system neuron development;GO:0050772//positive regulation of axonogenesis;GO:0051896//regulation of protein kinase B signaling;GO:0051965//positive regulation of synapse assembly;GO:0060041//retina development in camera-type eye;GO:0060291//long-term synaptic potentiation;GO:0071230//cellular response to amino acid stimulus;GO:0099183//trans-synaptic signaling by BDNF, modulating synaptic transmission;GO:0099551//trans-synaptic signaling by neuropeptide, modulating synaptic transmission;GO:1902430//negative regulation of amyloid-beta formation;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus;GO:2000811//negative regulation of anoikis"	--
ENSG00000148057	5.95	4.668	6.882	4.922	5.247	4	107	94	92	69	81	58	IDNK	IDNK gluconokinase [Source:HGNC Symbol;Acc:HGNC:31367]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00030//Pentose phosphate pathway	K00851;K00851;K00851	-	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046316//gluconokinase activity	GO:0005975//carbohydrate metabolic process;GO:0008150//biological_process;GO:0016310//phosphorylation;GO:0046177//D-gluconate catabolic process	--
ENSG00000148082	0.3	0.396	0.146	0.099	0.169	0.128	61	81	22	15	29	19	SHC3	SHC adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:18181]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune system;Substance dependence;Immune system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Drug resistance: antineoplastic;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system	"ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko01522//Endocrine resistance;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway"	K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448;K17448	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007417//central nervous system development;GO:0035556//intracellular signal transduction	--
ENSG00000148090	9.292	9.019	9.644	9.855	9.809	10.22	303	295	232	238	270	242	AUH	AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K05607;K05607	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity;GO:0004490//methylglutaconyl-CoA hydratase activity;GO:0016829//lyase activity;GO:0050011//itaconyl-CoA hydratase activity	GO:0006552//leucine catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000148110	22.674	22.417	26.076	21.523	19.424	24.93	1600	1590	1359	1125	1158	1280	MFSD14B	major facilitator superfamily domain containing 14B [Source:HGNC Symbol;Acc:HGNC:23376]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000148120	4.817	5.583	2.835	3.997	5.042	5.083	161	199	102	133	151	146	AOPEP	aminopeptidase O (putative) [Source:HGNC Symbol;Acc:HGNC:1361]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis	--
ENSG00000148123	0.564	0.538	0.253	0.263	0.484	0.319	29	26	9	10	21	6	PLPPR1	phospholipid phosphatase related 1 [Source:HGNC Symbol;Acc:HGNC:25993]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0042577//lipid phosphatase activity	GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0046839//phospholipid dephosphorylation	--
ENSG00000148136	0	0	0	0	0	0	0	0	0	0	0	0	OR13C4	olfactory receptor family 13 subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:14722]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000148143	3.68	3.302	2.845	2.178	2.877	2.629	585	573	365	296	443	300	ZNF462	zinc finger protein 462 [Source:HGNC Symbol;Acc:HGNC:21684]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006325//chromatin organization;GO:0010468//regulation of gene expression;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000148153	9.273	8.027	9.724	8.261	7.285	7.105	635	488	444	368	378	347	INIP	INTS3 and NABP interacting protein [Source:HGNC Symbol;Acc:HGNC:24994]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035861//site of double-strand break;GO:0070876//SOSS complex	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint	--
ENSG00000148154	6.198	5.428	4.897	3.863	4.411	4.971	509	448	297	235	306	297	UGCG	UDP-glucose ceramide glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:12524]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K00720;K00720	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008120//ceramide glucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0102769//dihydroceramide glucosyltransferase activity	GO:0006497//protein lipidation;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006679//glucosylceramide biosynthetic process;GO:0006687//glycosphingolipid metabolic process;GO:0008544//epidermis development;GO:0009966//regulation of signal transduction;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0033210//leptin-mediated signaling pathway;GO:0048666//neuron development;GO:0061436//establishment of skin barrier;GO:0098856//intestinal lipid absorption;GO:1903575//cornified envelope assembly	--
ENSG00000148156	0	0	0	0	0	0	0	0	0	0	0	0	ACTL7B	actin like 7B [Source:HGNC Symbol;Acc:HGNC:162]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0015629//actin cytoskeleton	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0007010//cytoskeleton organization	--
ENSG00000148158	12.835	12.147	11.258	9.044	10.064	9.982	2050	1950	1328	1070	1358	1160	SNX30	sorting nexin family member 30 [Source:HGNC Symbol;Acc:HGNC:23685]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding	GO:0015031//protein transport;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000148175	24.731	23.226	23.949	19.923	20.603	25.301	1551	1467	1110	926	1117	1144	STOM	stomatin [Source:HGNC Symbol;Acc:HGNC:3383]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0042470//melanosome;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0072562//blood microparticle	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0070063//RNA polymerase binding	GO:0034765//regulation of ion transmembrane transport;GO:0044829//positive regulation by host of viral genome replication;GO:0048524//positive regulation of viral process;GO:0090314//positive regulation of protein targeting to membrane;GO:1901585//regulation of acid-sensing ion channel activity	--
ENSG00000148180	141.288	144.049	159.386	119.253	121.346	131.132	7457	7675	6263	4653	5465	5107	GSN	gelsolin [Source:HGNC Symbol;Acc:HGNC:4620]	Cellular Processes;Human Diseases;Organismal Systems	Cell motility;Cancer: overview;Immune system	ko04810//Regulation of actin cytoskeleton;ko05203//Viral carcinogenesis;ko04666//Fc gamma R-mediated phagocytosis	K05768;K05768;K05768	GO:0001726//ruffle;GO:0002102//podosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016528//sarcoplasm;GO:0030027//lamellipodium;GO:0030478//actin cap;GO:0030864//cortical actin cytoskeleton;GO:0034774//secretory granule lumen;GO:0042470//melanosome;GO:0042995//cell projection;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904813//ficolin-1-rich granule lumen	"GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding;GO:0045159//myosin II binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding"	"GO:0006911//phagocytosis, engulfment;GO:0007417//central nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0010628//positive regulation of gene expression;GO:0014891//striated muscle atrophy;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0030042//actin filament depolymerization;GO:0031648//protein destabilization;GO:0035994//response to muscle stretch;GO:0042989//sequestering of actin monomers;GO:0045010//actin nucleation;GO:0046597//negative regulation of viral entry into host cell;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping;GO:0051127//positive regulation of actin nucleation;GO:0051693//actin filament capping;GO:0055119//relaxation of cardiac muscle;GO:0060271//cilium assembly;GO:0071346//cellular response to interferon-gamma;GO:0071801//regulation of podosome assembly;GO:0086003//cardiac muscle cell contraction;GO:0090527//actin filament reorganization;GO:0097017//renal protein absorption;GO:0097284//hepatocyte apoptotic process;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:1903903//regulation of establishment of T cell polarity;GO:1903906//regulation of plasma membrane raft polarization;GO:1903909//regulation of receptor clustering;GO:1903923//positive regulation of protein processing in phagocytic vesicle;GO:1990000//amyloid fibril formation;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"	--
ENSG00000148187	9.117	10.338	8.018	6.531	5.804	8.536	291	322	230	170	196	200	MRRF	mitochondrial ribosome recycling factor [Source:HGNC Symbol;Acc:HGNC:7234]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding	GO:0006412//translation;GO:0032790//ribosome disassembly	--
ENSG00000148200	0.456	0.21	0.834	0.404	0.992	0.291	60	31	50	33	34	31	NR6A1	nuclear receptor subfamily 6 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7985]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007276//gamete generation;GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II"	GCNF-like
ENSG00000148204	17.849	17.294	21.227	20.849	21.638	26.436	2048.93	1977.99	1812.62	1764.83	2094.63	2200.94	CRB2	crumbs cell polarity complex component 2 [Source:HGNC Symbol;Acc:HGNC:18688]	Environmental Information Processing	Signal transduction	ko04390//Hippo signaling pathway	K16681	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0035003//subapical complex;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0044877//protein-containing complex binding	GO:0001707//mesoderm formation;GO:0001756//somitogenesis;GO:0001895//retina homeostasis;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007369//gastrulation;GO:0007601//visual perception;GO:0010470//regulation of gastrulation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010951//negative regulation of endopeptidase activity;GO:0014028//notochord formation;GO:0030010//establishment of cell polarity;GO:0030513//positive regulation of BMP signaling pathway;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0045494//photoreceptor cell maintenance;GO:0046549//retinal cone cell development;GO:0050896//response to stimulus;GO:0055111//ingression involved in gastrulation with mouth forming second;GO:0072359//circulatory system development	--
ENSG00000148215	0	0	0	0	0	0	0	0	0	0	0	0	OR5C1	olfactory receptor family 5 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8331]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000148218	25.775	24.851	23.804	22.132	22.042	22.68	1658	1612	1141	1064	1191	1071	ALAD	aminolevulinate dehydratase [Source:HGNC Symbol;Acc:HGNC:395]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01698;K01698	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003824//catalytic activity;GO:0004655//porphobilinogen synthase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1904854//proteasome core complex binding	GO:0001666//response to hypoxia;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0006979//response to oxidative stress;GO:0007584//response to nutrient;GO:0008152//metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009635//response to herbicide;GO:0009636//response to toxic substance;GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010038//response to metal ion;GO:0010039//response to iron ion;GO:0010043//response to zinc ion;GO:0010044//response to aluminum ion;GO:0010212//response to ionizing radiation;GO:0010266//response to vitamin B1;GO:0010269//response to selenium ion;GO:0010288//response to lead ion;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0031667//response to nutrient levels;GO:0032025//response to cobalt ion;GO:0032496//response to lipopolysaccharide;GO:0033014//tetrapyrrole biosynthetic process;GO:0033197//response to vitamin E;GO:0033273//response to vitamin;GO:0043200//response to amino acid;GO:0045471//response to ethanol;GO:0046685//response to arsenic-containing substance;GO:0046686//response to cadmium ion;GO:0046689//response to mercury ion;GO:0051260//protein homooligomerization;GO:0051384//response to glucocorticoid;GO:0051597//response to methylmercury;GO:0070541//response to platinum ion;GO:0070542//response to fatty acid;GO:0071284//cellular response to lead ion;GO:0071353//cellular response to interleukin-4;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000148219	1.459	1.298	1.39	0.924	1.252	1.054	91.01	93	58	46	63	53	ASTN2	astrotactin 2 [Source:HGNC Symbol;Acc:HGNC:17021]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043204//perikaryon;GO:0060187//cell pole	"GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0046872//metal ion binding"	GO:0001764//neuron migration;GO:0007158//neuron cell-cell adhesion;GO:0015031//protein transport;GO:0048105//establishment of body hair planar orientation;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000148225	3.136	3.606	4.042	2.66	3.333	3.235	215	262	190	134	207	162	WDR31	WD repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:21421]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000148229	10.769	10.422	9.331	9.203	10.353	8.932	477	465	304	305	386	286	POLE3	"DNA polymerase epsilon 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:13546]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair	K02326;K02326;K02326	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0008622//epsilon DNA polymerase complex;GO:0008623//CHRAC;GO:0140672//ATAC complex	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0046982//protein heterodimerization activity	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006272//leading strand elongation;GO:0006275//regulation of DNA replication;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0031507//heterochromatin assembly;GO:0042766//nucleosome mobilization;GO:0043966//histone H3 acetylation;GO:0071897//DNA biosynthetic process	--
ENSG00000148248	112.5	122.423	116.627	123.748	122.825	114.093	6648	7231	5153	5387	6170	4913	SURF4	surfeit 4 [Source:HGNC Symbol;Acc:HGNC:11476]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031965//nuclear membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0035577//azurophil granule membrane	GO:0005515//protein binding;GO:0038024//cargo receptor activity	GO:0006897//endocytosis;GO:0007030//Golgi organization;GO:0010638//positive regulation of organelle organization;GO:0015031//protein transport;GO:0032368//regulation of lipid transport;GO:0042953//lipoprotein transport;GO:0055088//lipid homeostasis	--
ENSG00000148288	4.571	3.805	4.278	4.283	3.98	4.71	167.88	155.56	118	118.09	114	113	GBGT1	"globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) [Source:HGNC Symbol;Acc:HGNC:20460]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K00722;K00722	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0046872//metal ion binding;GO:0047277//globoside alpha-N-acetylgalactosaminyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0009247//glycolipid biosynthetic process;GO:0030259//lipid glycosylation	--
ENSG00000148290	20.883	21.841	24.527	24.199	20.38	22.148	473	496	406	406	390	365	SURF1	SURF1 cytochrome c oxidase assembly factor [Source:HGNC Symbol;Acc:HGNC:11474]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding	GO:0008535//respiratory chain complex IV assembly;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:1902600//proton transmembrane transport	--
ENSG00000148291	9.492	9.386	9.247	11.798	8.426	10.182	164	163	118	151	123	128	SURF2	surfeit 2 [Source:HGNC Symbol;Acc:HGNC:11475]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000148296	7.821	7.837	8.015	7.392	7.869	7.369	687	692	520	481	584	471	SURF6	surfeit 6 [Source:HGNC Symbol;Acc:HGNC:11478]	-	-	-	-	GO:0001652//granular component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000148297	13.721	12.772	15.617	13.963	17.074	13.939	1034	943	822	761	958	814	MED22	mediator complex subunit 22 [Source:HGNC Symbol;Acc:HGNC:11477]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000148300	14.631	15.28	17.738	17.902	16.611	17.659	697	741	631	633	671	610	REXO4	"REX4 homolog, 3'-5' exonuclease [Source:HGNC Symbol;Acc:HGNC:12820]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006364//rRNA processing"	--
ENSG00000148303	958.4	982.613	942.433	973.923	844.694	847.285	17632	18171	12808	13273	13130	11343	RPL7A	ribosomal protein L7a [Source:HGNC Symbol;Acc:HGNC:10364]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02936;K02936	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000470//maturation of LSU-rRNA;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0042254//ribosome biogenesis	--
ENSG00000148308	17.835	19.238	20.401	19.309	18.555	18.416	758	791	647	602	643	551	GTF3C5	general transcription factor IIIC subunit 5 [Source:HGNC Symbol;Acc:HGNC:4668]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0035914//skeletal muscle cell differentiation;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III	--
ENSG00000148331	7.833	8.712	10.453	10.509	8.875	9.979	655.73	702.41	617.84	614.37	620.35	627.14	ASB6	ankyrin repeat and SOCS box containing 6 [Source:HGNC Symbol;Acc:HGNC:17181]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification	--
ENSG00000148334	23.413	26.706	25.13	32.341	29.256	31.234	778	894	615	786	824	749	PTGES2	prostaglandin E synthase 2 [Source:HGNC Symbol;Acc:HGNC:17822]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K05309;K05309	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035578//azurophil granule lumen;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0036134//12-hydroxyheptadecatrienoic acid synthase activity;GO:0043295//glutathione binding;GO:0050220//prostaglandin-E synthase activity;GO:0097573//glutathione oxidoreductase activity	"GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0006749//glutathione metabolic process;GO:0019371//cyclooxygenase pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046903//secretion"	--
ENSG00000148335	16.38	15.716	17.455	19.658	18.896	20.239	394.27	400.59	331.16	344.63	364.65	337.86	NTMT1	N-terminal Xaa-Pro-Lys N-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23373]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0016740//transferase activity;GO:0042054//histone methyltransferase activity;GO:0071885//N-terminal protein N-methyltransferase activity	GO:0006480//N-terminal protein amino acid methylation;GO:0007051//spindle organization;GO:0007059//chromosome segregation;GO:0016571//histone methylation;GO:0018011//N-terminal peptidyl-alanine methylation;GO:0018012//N-terminal peptidyl-alanine trimethylation;GO:0018013//N-terminal peptidyl-glycine methylation;GO:0018016//N-terminal peptidyl-proline dimethylation;GO:0032259//methylation;GO:0035568//N-terminal peptidyl-proline methylation;GO:0035570//N-terminal peptidyl-serine methylation;GO:0035572//N-terminal peptidyl-serine dimethylation;GO:0035573//N-terminal peptidyl-serine trimethylation	--
ENSG00000148337	26.58	27.483	30.132	27.965	31.883	33.503	1604	1667	1281	1263	1481	1394	CIZ1	CDKN1A interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:16744]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030332//cyclin binding;GO:0046872//metal ion binding	GO:0032298//positive regulation of DNA-dependent DNA replication initiation;GO:0051457//maintenance of protein location in nucleus	Others
ENSG00000148339	4.242	3.519	4.384	4.21	4.514	5.922	282	257	234	224	276	293	SLC25A25	solute carrier family 25 member 25 [Source:HGNC Symbol;Acc:HGNC:20663]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005347//ATP transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0002021//response to dietary excess;GO:0014823//response to activity;GO:0015867//ATP transport;GO:0032094//response to food;GO:0035264//multicellular organism growth;GO:0043010//camera-type eye development;GO:0045333//cellular respiration;GO:0046034//ATP metabolic process;GO:0055085//transmembrane transport;GO:0060612//adipose tissue development;GO:0070588//calcium ion transmembrane transport	--
ENSG00000148341	20.511	21.555	22.066	24.165	28.048	24.122	794	796	563	648	738	548	SH3GLB2	"SH3 domain containing GRB2 like, endophilin B2 [Source:HGNC Symbol;Acc:HGNC:10834]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K21269	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	GO:0061024//membrane organization	--
ENSG00000148343	5.768	5.967	5.929	7.006	7.437	7.857	441	457	335	396	475	437	MIGA2	mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0008053//mitochondrial fusion;GO:0060348//bone development	--
ENSG00000148344	1.404	2.054	1.454	3.643	2.835	3.103	51	75	39	98	87	82	PTGES	prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K15729;K15729	GO:0005641//nuclear envelope lumen;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0004667//prostaglandin-D synthase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016853//isomerase activity;GO:0043295//glutathione binding;GO:0050220//prostaglandin-E synthase activity	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0019233//sensory perception of pain;GO:0031620//regulation of fever generation;GO:0032308//positive regulation of prostaglandin secretion;GO:0050727//regulation of inflammatory response;GO:0098869//cellular oxidant detoxification	--
ENSG00000148346	0.059	0	0	0	0.139	0	1	0	0	0	2	0	LCN2	lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21129	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0035580//specific granule lumen;GO:0060205//cytoplasmic vesicle lumen;GO:0070062//extracellular exosome	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0042802//identical protein binding;GO:1903981//enterobactin binding	GO:0002376//immune system process;GO:0006811//ion transport;GO:0006915//apoptotic process;GO:0015891//siderophore transport;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0055072//iron ion homeostasis;GO:0097577//sequestering of iron ion;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000148356	7.579	8.212	7.879	9.257	8.662	7.218	512	553	395	466	491	353	LRSAM1	leucine rich repeat and sterile alpha motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25135]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0045806//negative regulation of endocytosis;GO:0046755//viral budding;GO:0051865//protein autoubiquitination;GO:0070086//ubiquitin-dependent endocytosis;GO:1904417//positive regulation of xenophagy;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000148357	0	0	0.014	0	0	0.017	0	0	3	0	0	4	HMCN2	hemicentin 2 [Source:HGNC Symbol;Acc:HGNC:21293]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0032154//cleavage furrow;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0050896//response to stimulus	--
ENSG00000148358	23.103	23.775	24.354	22.046	23.966	23.68	3213	3336	2521	2287	2843	2411	GPR107	G protein-coupled receptor 107 [Source:HGNC Symbol;Acc:HGNC:17830]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle	GO:0032050//clathrin heavy chain binding	GO:0072583//clathrin-dependent endocytosis	--
ENSG00000148362	7.518	9.914	8.079	12.324	12.501	11.645	126	167	100	153	177	142	PAXX	PAXX non-homologous end joining factor [Source:HGNC Symbol;Acc:HGNC:27849]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0035861//site of double-strand break;GO:0043564//Ku70:Ku80 complex;GO:0070419//nonhomologous end joining complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0060090//molecular adaptor activity;GO:0070182//DNA polymerase binding	GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000148377	0	0	0	0	0.093	0	0	0	0	0	2.22	0	IDI2	isopentenyl-diphosphate delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:23487]	Metabolism;Metabolism	Global and overview maps;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko00900//Terpenoid backbone biosynthesis	K01823;K01823	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004452//isopentenyl-diphosphate delta-isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0009240//isopentenyl diphosphate biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0046490//isopentenyl diphosphate metabolic process;GO:0050992//dimethylallyl diphosphate biosynthetic process	--
ENSG00000148384	3.866	4.015	5.095	4.813	4.96	5.003	274	286	266	251	297	258	INPP5E	inositol polyphosphate-5-phosphatase E [Source:HGNC Symbol;Acc:HGNC:21474]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K20278;K20278;K20278	GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0042995//cell projection	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0106019//phosphatidylinositol-4,5-bisphosphate phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008150//biological_process;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0017148//negative regulation of translation;GO:0046488//phosphatidylinositol metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:1903565//negative regulation of protein localization to cilium	--
ENSG00000148386	0	0	0	0	0	0	0	0	0	0	0	0	LCN9	lipocalin 9 [Source:HGNC Symbol;Acc:HGNC:17442]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0036094//small molecule binding	-	--
ENSG00000148396	21.335	22.013	23.404	21.602	23.726	22.044	3475	3647	2722	2567	3150	2501	SEC16A	"SEC16 homolog A, endoplasmic reticulum export factor [Source:HGNC Symbol;Acc:HGNC:29006]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0021762//substantia nigra development;GO:0032527//protein exit from endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0043000//Golgi to plasma membrane CFTR protein transport;GO:0046907//intracellular transport;GO:0048208//COPII vesicle coating;GO:0050821//protein stabilization;GO:0070973//protein localization to endoplasmic reticulum exit site;GO:0072659//protein localization to plasma membrane	--
ENSG00000148399	5.152	4.751	4.112	4.382	4.313	5.728	246	228	145	155	174	199	DPH7	diphthamide biosynthesis 7 [Source:HGNC Symbol;Acc:HGNC:25199]	-	-	-	-	-	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0061685//diphthine methylesterase activity	GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine	--
ENSG00000148400	8.651	9.625	8.591	7.406	9.461	9.675	1718	1921	1261	1087	1588	1397	NOTCH1	notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Neurodegenerative disease;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05020//Prion disease;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K02599;K02599;K02599;K02599;K02599;K02599;K02599;K02599;K02599	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0002193//MAML1-RBP-Jkappa- ICN1 complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex;GO:0071944//cell periphery	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0004857//enzyme inhibitor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031490//chromatin DNA binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0001837//epithelial to mesenchymal transition;GO:0001889//liver development;GO:0001947//heart looping;GO:0002040//sprouting angiogenesis;GO:0002052//positive regulation of neuroblast proliferation;GO:0002437//inflammatory response to antigenic stimulus;GO:0003151//outflow tract morphogenesis;GO:0003157//endocardium development;GO:0003160//endocardium morphogenesis;GO:0003162//atrioventricular node development;GO:0003169//coronary vein morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003182//coronary sinus valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003192//mitral valve formation;GO:0003197//endocardial cushion development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003203//endocardial cushion morphogenesis;GO:0003207//cardiac chamber formation;GO:0003208//cardiac ventricle morphogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0003213//cardiac right atrium morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0003219//cardiac right ventricle formation;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003241//growth involved in heart morphogenesis;GO:0003252//negative regulation of cell proliferation involved in heart valve morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0003264//regulation of cardioblast proliferation;GO:0003270//Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation;GO:0003273//cell migration involved in endocardial cushion formation;GO:0003332//negative regulation of extracellular matrix constituent secretion;GO:0003344//pericardium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0007368//determination of left/right symmetry;GO:0007386//compartment pattern specification;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007440//foregut morphogenesis;GO:0007492//endoderm development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008544//epidermis development;GO:0008593//regulation of Notch signaling pathway;GO:0009912//auditory receptor cell fate commitment;GO:0010001//glial cell differentiation;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010812//negative regulation of cell-substrate adhesion;GO:0010832//negative regulation of myotube differentiation;GO:0014031//mesenchymal cell development;GO:0014807//regulation of somitogenesis;GO:0021515//cell differentiation in spinal cord;GO:0021915//neural tube development;GO:0030154//cell differentiation;GO:0030163//protein catabolic process;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0030279//negative regulation of ossification;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0031069//hair follicle morphogenesis;GO:0031100//animal organ regeneration;GO:0031960//response to corticosteroid;GO:0032495//response to muramyl dipeptide;GO:0032496//response to lipopolysaccharide;GO:0035116//embryonic hindlimb morphogenesis;GO:0035148//tube formation;GO:0035914//skeletal muscle cell differentiation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042127//regulation of cell population proliferation;GO:0042246//tissue regeneration;GO:0043065//positive regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0045070//positive regulation of viral genome replication;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045607//regulation of inner ear auditory receptor cell differentiation;GO:0045608//negative regulation of inner ear auditory receptor cell differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048103//somatic stem cell division;GO:0048663//neuron fate commitment;GO:0048708//astrocyte differentiation;GO:0048709//oligodendrocyte differentiation;GO:0048711//positive regulation of astrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048845//venous blood vessel morphogenesis;GO:0048873//homeostasis of number of cells within a tissue;GO:0050678//regulation of epithelial cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050767//regulation of neurogenesis;GO:0050768//negative regulation of neurogenesis;GO:0050793//regulation of developmental process;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060253//negative regulation of glial cell proliferation;GO:0060271//cilium assembly;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060354//negative regulation of cell adhesion molecule production;GO:0060411//cardiac septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0060548//negative regulation of cell death;GO:0060740//prostate gland epithelium morphogenesis;GO:0060768//regulation of epithelial cell proliferation involved in prostate gland development;GO:0060842//arterial endothelial cell differentiation;GO:0060843//venous endothelial cell differentiation;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060956//endocardial cell differentiation;GO:0060979//vasculogenesis involved in coronary vascular morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0061384//heart trabecula morphogenesis;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0062043//positive regulation of cardiac epithelial to mesenchymal transition;GO:0070168//negative regulation of biomineral tissue development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070986//left/right axis specification;GO:0071228//cellular response to tumor cell;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0072017//distal tubule development;GO:0072044//collecting duct development;GO:0072144//glomerular mesangial cell development;GO:0072538//T-helper 17 type immune response;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:0097400//interleukin-17-mediated signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901201//regulation of extracellular matrix assembly;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:1902339//positive regulation of apoptotic process involved in morphogenesis;GO:1903849//positive regulation of aorta morphogenesis;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000737//negative regulation of stem cell differentiation;GO:2000811//negative regulation of anoikis;GO:2000974//negative regulation of pro-B cell differentiation;GO:2001027//negative regulation of endothelial cell chemotaxis"	--
ENSG00000148408	0.02	0.015	0.04	0.055	0	0.028	3	3	6	6	0	3	CACNA1B	calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Cancer: overview;Nervous system;Nervous system;Nervous system;Nervous system;Substance dependence;Nervous system;Nervous system;Endocrine and metabolic disease;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05207//Chemical carcinogenesis - receptor activation;ko04723//Retrograde endocannabinoid signaling;ko04728//Dopaminergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle;ko04930//Type II diabetes mellitus;ko05033//Nicotine addiction	K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849;K04849	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0001540//amyloid-beta binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008331//high voltage-gated calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0030001//metal ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0050804//modulation of chemical synaptic transmission;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:1904645//response to amyloid-beta	--
ENSG00000148411	24.574	22.539	23.411	22.629	22.061	27.442	3489	3221	2469	2384	2660	2839	NACC2	NACC family member 2 [Source:HGNC Symbol;Acc:HGNC:23846]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0044877//protein-containing complex binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0031503//protein-containing complex localization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051260//protein homooligomerization;GO:1900477//negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage"	--
ENSG00000148426	1.628	1.606	1.449	1.646	2.49	2.097	114	113	62	83	120	98	PROSER2	proline and serine rich 2 [Source:HGNC Symbol;Acc:HGNC:23728]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000148429	8.42	7.436	7.039	6.989	6.562	7.473	757	668.03	475	435	495	485	USP6NL	USP6 N-terminal like [Source:HGNC Symbol;Acc:HGNC:16858]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane	GO:0005096//GTPase activator activity;GO:0031267//small GTPase binding	"GO:0007030//Golgi organization;GO:0019068//virion assembly;GO:0035526//retrograde transport, plasma membrane to Golgi;GO:0043547//positive regulation of GTPase activity;GO:0048227//plasma membrane to endosome transport;GO:0090630//activation of GTPase activity;GO:1903358//regulation of Golgi organization"	--
ENSG00000148444	14.806	12.276	13.817	11.77	11.129	12.164	283	237	196	167	179.12	170	COMMD3	COMM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23332]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport	--
ENSG00000148450	6.229	5.966	5.66	6.584	6.012	3.677	218	210	150	175	173	96	MSRB2	methionine sulfoxide reductase B2 [Source:HGNC Symbol;Acc:HGNC:17061]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0003779//actin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0046872//metal ion binding"	GO:0006979//response to oxidative stress;GO:0030041//actin filament polymerization;GO:0030091//protein repair	--
ENSG00000148459	4.965	4.636	3.833	2.26	2.63	3.765	162	151	93	55	73	90	PDSS1	decaprenyl diphosphate synthase subunit 1 [Source:HGNC Symbol;Acc:HGNC:17759]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K12504	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:1990234//transferase complex	GO:0000010//trans-hexaprenyltranstransferase activity;GO:0004659//prenyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0097269//all-trans-decaprenyl-diphosphate synthase activity	GO:0006629//lipid metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0008299//isoprenoid biosynthetic process	--
ENSG00000148468	16.849	16.424	16.639	13.945	14.614	15.61	1445	1432	1066	896	1071	941	FAM171A1	family with sequence similarity 171 member A1 [Source:HGNC Symbol;Acc:HGNC:23522]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008360//regulation of cell shape;GO:0043149//stress fiber assembly	--
ENSG00000148481	12.535	10.935	12.187	10.474	9.489	10.774	604	523	430	367	374	382	MINDY3	MINDY lysine 48 deubiquitinase 3 [Source:HGNC Symbol;Acc:HGNC:23578]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000148482	234.903	220.159	247.347	187.6	201.139	241.914	13240	12479	10297	7837	9581	9924	SLC39A12	solute carrier family 39 member 12 [Source:HGNC Symbol;Acc:HGNC:20860]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14718;K14718	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:1903561//extracellular vesicle	GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0007165//signal transduction;GO:0010975//regulation of neuron projection development;GO:0030001//metal ion transport;GO:0031113//regulation of microtubule polymerization;GO:0036293//response to decreased oxygen levels;GO:0055085//transmembrane transport;GO:0071578//zinc ion import across plasma membrane;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000148483	0.114	0.026	0.012	0.059	0.021	0.036	13	3	1	5	2	3	TMEM236	transmembrane protein 236 [Source:HGNC Symbol;Acc:HGNC:23473]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000148484	20.372	18.433	18.374	16.975	17.587	17.567	1581	1438	1049	974	1150	994	RSU1	Ras suppressor protein 1 [Source:HGNC Symbol;Acc:HGNC:10464]	-	-	-	-	GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0010811//positive regulation of cell-substrate adhesion;GO:0043547//positive regulation of GTPase activity	--
ENSG00000148488	0.701	0.309	0.31	0.209	0.212	0.171	48	45	31	19	26	15	ST8SIA6	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:23317]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0001835//blastocyst hatching;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006493//protein O-linked glycosylation;GO:0006629//lipid metabolic process;GO:0009100//glycoprotein metabolic process;GO:0009247//glycolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0097503//sialylation	--
ENSG00000148498	13.511	13.627	12.911	11.075	11.343	11.868	1221	1250	851	795	865	818	PARD3	par-3 family cell polarity regulator [Source:HGNC Symbol;Acc:HGNC:16051]	Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Infectious disease: viral;Transport and catabolism;Signal transduction;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Cellular community - eukaryotes	ko04080//Neuroactive ligand-receptor interaction;ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04520//Adherens junction	K04237;K04237;K04237;K04237;K04237;K04237;K04237;K04237;K04237	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0033269//internode region of axon;GO:0043296//apical junction complex;GO:0070160//tight junction;GO:0120157//PAR polarity complex	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding"	GO:0000226//microtubule cytoskeleton organization;GO:0006612//protein targeting to membrane;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007409//axonogenesis;GO:0008104//protein localization;GO:0008356//asymmetric cell division;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0022011//myelination in peripheral nervous system;GO:0030010//establishment of cell polarity;GO:0030154//cell differentiation;GO:0031643//positive regulation of myelination;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0051301//cell division;GO:0051660//establishment of centrosome localization;GO:0065003//protein-containing complex assembly;GO:0070830//bicellular tight junction assembly;GO:0090162//establishment of epithelial cell polarity	--
ENSG00000148513	0	0	0	0	0	0	0	0	0	0	0	0	ANKRD30A	ankyrin repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:17234]	-	-	-	-	-	GO:0005515//protein binding	-	Others
ENSG00000148516	3.867	3.259	2.987	1.437	2.624	2.103	395	335	217	123	175	142	ZEB1	zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05206//MicroRNAs in cancer;ko05215//Prostate cancer	K09299;K09299;K09299	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043226//organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070888//E-box binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0010464//regulation of mesenchymal cell proliferation;GO:0014823//response to activity;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030154//cell differentiation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0033081//regulation of T cell differentiation in thymus;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048598//embryonic morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0048856//anatomical structure development;GO:0051150//regulation of smooth muscle cell differentiation;GO:0051216//cartilage development;GO:0071230//cellular response to amino acid stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090103//cochlea morphogenesis"	zf-C2H2
ENSG00000148541	3.117	2.397	3.133	2.962	3.297	3.852	158.3	133.24	108.59	100.7	110.04	106.71	FAM13C	family with sequence similarity 13 member C [Source:HGNC Symbol;Acc:HGNC:19371]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000148572	12.923	11.587	12.817	10.23	10.794	12.827	486	438	356	285	343	351	NRBF2	nuclear receptor binding factor 2 [Source:HGNC Symbol;Acc:HGNC:19692]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia	K21246;K21246;K21246;K21246;K21246;K21246	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0031410//cytoplasmic vesicle;GO:0035032//phosphatidylinositol 3-kinase complex, class III"	GO:0005515//protein binding	GO:0006914//autophagy;GO:0034976//response to endoplasmic reticulum stress;GO:0043550//regulation of lipid kinase activity	--
ENSG00000148584	0	0	0.007	0	0	0	0	0	1	0	0	0	A1CF	APOBEC1 complementation factor [Source:HGNC Symbol;Acc:HGNC:24086]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0045293//mRNA editing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0006397//mRNA processing;GO:0007566//embryo implantation;GO:0010609//mRNA localization resulting in posttranscriptional regulation of gene expression;GO:0016554//cytidine to uridine editing;GO:0016556//mRNA modification;GO:0050821//protein stabilization;GO:1901537//positive regulation of DNA demethylation;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000148600	9.411	6.336	9.027	5.534	7.839	8.953	808	618	665	424	570	609	CDHR1	cadherin related family member 1 [Source:HGNC Symbol;Acc:HGNC:14550]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane	GO:0003674//molecular_function;GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008594//photoreceptor cell morphogenesis;GO:0035845//photoreceptor cell outer segment organization;GO:0045494//photoreceptor cell maintenance;GO:0098609//cell-cell adhesion	--
ENSG00000148602	0.121	0.04	0.055	0.027	0.024	0.028	6	2	2	1	1	1	LRIT1	"leucine rich repeat, Ig-like and transmembrane domains 1 [Source:HGNC Symbol;Acc:HGNC:23404]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000148604	117.685	114.89	154.455	126.203	112.072	124.239	3416	3451	3252	2707	2767	2584	RGR	retinal G protein coupled receptor [Source:HGNC Symbol;Acc:HGNC:9990]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000148606	6.856	6.342	6.755	6.873	7.238	7.358	940	874	684	698	797	734	POLR3A	RNA polymerase III subunit A [Source:HGNC Symbol;Acc:HGNC:30074]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03018;K03018	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol;GO:0016020//membrane	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006351//transcription, DNA-templated;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0051607//defense response to virus"	--
ENSG00000148634	7.088	6.093	5.832	5.047	5.727	6.549	644	543	392	333	435	429	HERC4	HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:24521]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10615	GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity	GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0045879//negative regulation of smoothened signaling pathway	--
ENSG00000148655	3.2	2.183	1.412	1.854	3.976	4.369	56	46	37	34	43	45	LRMDA	leucine rich melanocyte differentiation associated [Source:HGNC Symbol;Acc:HGNC:23405]	-	-	-	-	-	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0030318//melanocyte differentiation	--
ENSG00000148660	7.696	8.79	7.493	7.639	9.375	7.64	481	537	358	342	483	361	CAMK2G	calcium/calmodulin dependent protein kinase II gamma [Source:HGNC Symbol;Acc:HGNC:1463]	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Development and regeneration;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Circulatory system;Cell growth and death;Nervous system;Nervous system;Signal transduction;Nervous system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Endocrine system;Endocrine system;Endocrine system;Signal transduction;Cancer: specific types;Digestive system;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04217//Necroptosis;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko05214//Glioma;ko04971//Gastric acid secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515;K04515	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030666//endocytic vesicle membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0043005//neuron projection;GO:0043226//organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007399//nervous system development;GO:0010975//regulation of neuron projection development;GO:0014733//regulation of skeletal muscle adaptation;GO:0016310//phosphorylation;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0051924//regulation of calcium ion transport	--
ENSG00000148671	0	0.153	0	0.208	0.819	0	0	2	0	2	9	0	ADIRF	adipogenesis regulatory factor [Source:HGNC Symbol;Acc:HGNC:24043]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000148672	28.304	30.71	32.267	30.965	30.115	31.157	1752.8	1912.19	1462.89	1392.03	1617.31	1427.9	GLUD1	glutamate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:4335]	Metabolism;Cellular Processes;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Cell growth and death;Global and overview maps;Amino acid metabolism;Excretory system;Amino acid metabolism;Energy metabolism	"ko01100//Metabolic pathways;ko04217//Necroptosis;ko01200//Carbon metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko04964//Proximal tubule bicarbonate reclamation;ko00220//Arginine biosynthesis;ko00910//Nitrogen metabolism"	K00261;K00261;K00261;K00261;K00261;K00261;K00261	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum	"GO:0000166//nucleotide binding;GO:0004352//glutamate dehydrogenase (NAD+) activity;GO:0004353//glutamate dehydrogenase [NAD(P)+] activity;GO:0004354//glutamate dehydrogenase (NADP+) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016491//oxidoreductase activity;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0070403//NAD+ binding;GO:0070728//leucine binding"	GO:0006520//cellular amino acid metabolic process;GO:0006537//glutamate biosynthetic process;GO:0006538//glutamate catabolic process;GO:0006541//glutamine metabolic process;GO:0021762//substantia nigra development;GO:0032024//positive regulation of insulin secretion;GO:0072350//tricarboxylic acid metabolic process	--
ENSG00000148677	27.499	27.707	14.368	1.454	4.176	2.295	1021	1034	394	40	131	62	ANKRD1	ankyrin repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:15819]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030016//myofibril;GO:0031674//I band;GO:0032991//protein-containing complex	GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0031432//titin binding;GO:0042826//histone deacetylase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412//R-SMAD binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0035914//skeletal muscle cell differentiation;GO:0035994//response to muscle stretch;GO:0043065//positive regulation of apoptotic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045214//sarcomere organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050714//positive regulation of protein secretion;GO:0055008//cardiac muscle tissue morphogenesis;GO:0070528//protein kinase C signaling;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071466//cellular response to xenobiotic stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000279//negative regulation of DNA biosynthetic process"	--
ENSG00000148680	0.193	0.19	0.022	0.129	0.151	0.153	13	12	1	6	8	7	HTR7	5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04014//Ras signaling pathway;ko04726//Serotonergic synapse	K04163;K04163;K04163;K04163	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0032588//trans-Golgi network membrane;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity	"GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007623//circadian rhythm;GO:0008015//blood circulation;GO:0042310//vasoconstriction;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000148688	9.328	9.773	10.082	7.743	9.637	8.879	235	230	179	141	196	170	RPP30	ribonuclease P/MRP subunit p30 [Source:HGNC Symbol;Acc:HGNC:17688]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K03539	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000148690	2.838	2.87	3.128	2.261	3.157	3.218	183	186	149	108	172	151	FRA10AC1	FRA10A associated CGG repeat 1 [Source:HGNC Symbol;Acc:HGNC:1162]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0016791//phosphatase activity	GO:0016311//dephosphorylation	--
ENSG00000148700	85.268	71.793	72.834	57.358	60.925	71.575	7689	6525	4867	3841	4637	4715	ADD3	adducin 3 [Source:HGNC Symbol;Acc:HGNC:245]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005516//calmodulin binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0051016//barbed-end actin filament capping	--
ENSG00000148702	0	0	0	0	0.019	0	0	0	0	0	1	0	HABP2	hyaluronan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4798]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007596//blood coagulation	--
ENSG00000148704	0	0	0	0.034	0	0	0	0	0	1	0	0	VAX1	ventral anterior homeobox 1 [Source:HGNC Symbol;Acc:HGNC:12660]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007406//negative regulation of neuroblast proliferation;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0043010//camera-type eye development;GO:0060021//roof of mouth development"	Homeobox
ENSG00000148719	23.653	23.46	23.561	25.791	24.679	25.811	1432	1497	1061	1156	1245	1176	DNAJB12	DnaJ heat shock protein family (Hsp40) member B12 [Source:HGNC Symbol;Acc:HGNC:14891]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09518	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031965//nuclear membrane	GO:0030544//Hsp70 protein binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034622//cellular protein-containing complex assembly;GO:0036503//ERAD pathway;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein	--
ENSG00000148730	62.975	62.474	66.201	61.437	64.469	62.935	9785	9757	7597	7071	8463	7115	EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3289]	Organismal Systems	Aging	ko04213//Longevity regulating pathway - multiple species	K18644	GO:0005737//cytoplasm	GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0030371//translation repressor activity	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0007613//memory;GO:0008286//insulin receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0031929//TOR signaling;GO:0035176//social behavior;GO:0045947//negative regulation of translational initiation;GO:0048167//regulation of synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission	--
ENSG00000148734	25.146	24.612	32.706	47.866	44.577	48.307	4824	4746	4634	6802	7225	6743	NPFFR1	neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04240	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008150//biological_process	--
ENSG00000148735	0	0	0	0	0.041	0	0	0	0	0	3	0	PLEKHS1	pleckstrin homology domain containing S1 [Source:HGNC Symbol;Acc:HGNC:26285]	-	-	-	-	-	-	-	--
ENSG00000148737	7.243	6.51	5.741	4.366	5.395	5.602	369	364	209	218	250	229	TCF7L2	transcription factor 7 like 2 [Source:HGNC Symbol;Acc:HGNC:11641]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05132//Salmonella infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04936//Alcoholic liver disease;ko04916//Melanogenesis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491;K04491	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0032993//protein-DNA complex;GO:0070369//beta-catenin-TCF7L2 complex;GO:0071664//catenin-TCF7L2 complex;GO:1990907//beta-catenin-TCF complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016922//nuclear receptor binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0045295//gamma-catenin binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070016//armadillo repeat domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009749//response to glucose;GO:0010909//positive regulation of heparan sulfate proteoglycan biosynthetic process;GO:0016055//Wnt signaling pathway;GO:0031016//pancreas development;GO:0032024//positive regulation of insulin secretion;GO:0032092//positive regulation of protein binding;GO:0032350//regulation of hormone metabolic process;GO:0042593//glucose homeostasis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043570//maintenance of DNA repeat elements;GO:0044334//canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition;GO:0045444//fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046827//positive regulation of protein export from nucleus;GO:0048625//myoblast fate commitment;GO:0048660//regulation of smooth muscle cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0060070//canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	HMG
ENSG00000148773	0.163	0.235	0.087	0.15	0.19	0.116	43	56	17	28	38	21	MKI67	marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107]	-	-	-	-	GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding	GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0008283//cell population proliferation;GO:0051983//regulation of chromosome segregation;GO:1902275//regulation of chromatin organization	--
ENSG00000148795	0.061	0	0	0	0	0	2	0	0	0	0	0	CYP17A1	cytochrome P450 family 17 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2593]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Endocrine system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04917//Prolactin signaling pathway;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K00512;K00512;K00512;K00512;K00512;K00512	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004508//steroid 17-alpha-monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016829//lyase activity;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0047442//17-alpha-hydroxyprogesterone aldolase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0007548//sex differentiation;GO:0008202//steroid metabolic process;GO:0042446//hormone biosynthetic process;GO:0042448//progesterone metabolic process	--
ENSG00000148798	0.46	0.431	0.229	0.224	0.281	0.285	31	29.19	11.42	11.21	16	14	INA	internexin neuronal intermediate filament protein alpha [Source:HGNC Symbol;Acc:HGNC:6057]	-	-	-	-	GO:0005615//extracellular space;GO:0005882//intermediate filament;GO:0005883//neurofilament;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0098973//structural constituent of postsynaptic actin cytoskeleton;GO:0099184//structural constituent of postsynaptic intermediate filament cytoskeleton	GO:0007399//nervous system development;GO:0021762//substantia nigra development;GO:0030154//cell differentiation;GO:0045104//intermediate filament cytoskeleton organization;GO:0060052//neurofilament cytoskeleton organization;GO:0098974//postsynaptic actin cytoskeleton organization;GO:0099185//postsynaptic intermediate filament cytoskeleton organization;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000148803	10.764	10.123	12.459	9.112	11.743	8.706	155	148	134	96	144	91	FUOM	fucose mutarotase [Source:HGNC Symbol;Acc:HGNC:24733]	-	-	-	-	GO:0005829//cytosol	"GO:0016853//isomerase activity;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0036373//L-fucose mutarotase activity;GO:0042806//fucose binding;GO:0048029//monosaccharide binding"	GO:0005996//monosaccharide metabolic process;GO:0006004//fucose metabolic process;GO:0036065//fucosylation	--
ENSG00000148814	10.333	9.9	10.593	8.027	9.627	8.139	451	443	360	271	357.04	265	LRRC27	leucine rich repeat containing 27 [Source:HGNC Symbol;Acc:HGNC:29346]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000148824	17.29	17.468	17.27	18.778	18.487	19.721	540.03	546.3	382.6	442.17	467.02	421.51	MTG1	mitochondrial ribosome associated GTPase 1 [Source:HGNC Symbol;Acc:HGNC:32159]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005761//mitochondrial ribosome;GO:0016020//membrane;GO:0043232//intracellular non-membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006417//regulation of translation;GO:0044065//regulation of respiratory system process;GO:0070129//regulation of mitochondrial translation	--
ENSG00000148826	0	0	0	0	0	0	0	0	0	0	0	0	NKX6-2	NK6 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:19321]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010454//negative regulation of cell fate commitment;GO:0010455//positive regulation of cell fate commitment;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0031018//endocrine pancreas development;GO:0031641//regulation of myelination;GO:0045686//negative regulation of glial cell differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048709//oligodendrocyte differentiation;GO:0050885//neuromuscular process controlling balance"	Homeobox
ENSG00000148832	4.153	3.826	5.12	5.26	4.29	4.085	157	142.62	142.86	146.77	134	112	PAOX	polyamine oxidase [Source:HGNC Symbol;Acc:HGNC:20837]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K00308	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	"GO:0016491//oxidoreductase activity;GO:0046592//polyamine oxidase activity;GO:0052899//N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0052901//spermine:oxygen oxidoreductase (spermidine-forming) activity;GO:0052902//spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity;GO:0052903//N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0052904//N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity"	GO:0006598//polyamine catabolic process;GO:0008215//spermine metabolic process;GO:0009446//putrescine biosynthetic process;GO:0009447//putrescine catabolic process;GO:0046203//spermidine catabolic process;GO:0046208//spermine catabolic process;GO:1901307//positive regulation of spermidine biosynthetic process	--
ENSG00000148834	34.725	30.861	35.004	37.682	34.532	31.153	587	526	437	472	494	384	GSTO1	glutathione S-transferase omega 1 [Source:HGNC Symbol;Acc:HGNC:13312]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0050610//methylarsonate reductase activity	GO:0006749//glutathione metabolic process;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0014810//positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0019852//L-ascorbic acid metabolic process;GO:0042178//xenobiotic catabolic process;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0071243//cellular response to arsenic-containing substance;GO:0071704//organic substance metabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000148835	1.002	0.824	1.324	0.539	0.62	1.066	66	56	65	27	35	52	TAF5	TATA-box binding protein associated factor 5 [Source:HGNC Symbol;Acc:HGNC:11539]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03130	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0015629//actin cytoskeleton;GO:0033276//transcription factor TFTC complex	GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0042802//identical protein binding	"GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000148840	5.8	6.355	6.932	6.159	7.314	6.218	568	687	477	458	547	494	PPRC1	PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0030374//nuclear receptor coactivator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity"	--
ENSG00000148841	16.149	17.453	18.799	19.33	21.348	20.318	1498	1610	1290	1301	1641	1371	ITPRIP	"inositol 1,4,5-trisphosphate receptor interacting protein [Source:HGNC Symbol;Acc:HGNC:29370]"	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000148842	14.864	16.413	17.337	15.402	17.257	19.329	1835.15	1808.73	1613.83	1439.18	1708	1663.84	CNNM2	cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005524//ATP binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0010960//magnesium ion homeostasis;GO:0015693//magnesium ion transport;GO:0055085//transmembrane transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000148843	7.134	7.408	7.429	6.945	7.067	6.022	943	954	708	675	754	573	PDCD11	programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0032040//small-subunit processome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0051059//NF-kappaB binding	GO:0006364//rRNA processing;GO:0006396//RNA processing	--
ENSG00000148848	1.475	1.474	0.867	0.434	0.46	0.492	243	238	103	53	64	59	ADAM12	ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190]	-	-	-	-	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007520//myoblast fusion;GO:0045766//positive regulation of angiogenesis	--
ENSG00000148908	0.433	0.312	0.476	0.353	0.919	0.481	8	6	6	4	14	6	RGS10	regulator of G protein signaling 10 [Source:HGNC Symbol;Acc:HGNC:9992]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0045202//synapse	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0043547//positive regulation of GTPase activity	--
ENSG00000148925	10.177	8.815	9.255	8.972	8.136	9.287	442	396	325	287	318	291	BTBD10	BTB domain containing 10 [Source:HGNC Symbol;Acc:HGNC:21445]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0042327//positive regulation of phosphorylation;GO:0044342//type B pancreatic cell proliferation;GO:1901215//negative regulation of neuron death	--
ENSG00000148926	4.606	6.079	3.312	6.003	5.356	3.109	143	184	69	117	142	70	ADM	adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction	K12333;K12333	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0031700//adrenomedullin receptor binding	GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001843//neural tube closure;GO:0002026//regulation of the force of heart contraction;GO:0002031//G protein-coupled receptor internalization;GO:0003073//regulation of systemic arterial blood pressure;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007568//aging;GO:0008209//androgen metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009409//response to cold;GO:0009611//response to wounding;GO:0010033//response to organic substance;GO:0010460//positive regulation of heart rate;GO:0019933//cAMP-mediated signaling;GO:0031100//animal organ regeneration;GO:0031102//neuron projection regeneration;GO:0031623//receptor internalization;GO:0032496//response to lipopolysaccharide;GO:0032868//response to insulin;GO:0035809//regulation of urine volume;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042594//response to starvation;GO:0043065//positive regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0045766//positive regulation of angiogenesis;GO:0045906//negative regulation of vasoconstriction;GO:0046879//hormone secretion;GO:0048589//developmental growth;GO:0051384//response to glucocorticoid;GO:0055074//calcium ion homeostasis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060712//spongiotrophoblast layer development;GO:0097084//vascular associated smooth muscle cell development;GO:0097647//amylin receptor signaling pathway;GO:1990410//adrenomedullin receptor signaling pathway;GO:2000184//positive regulation of progesterone biosynthetic process;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000148935	0.582	0.576	0.701	0.582	0.638	1.284	27	22	24	20	25	16	GAS2	growth arrest specific 2 [Source:HGNC Symbol;Acc:HGNC:4167]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0016020//membrane	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal anchor activity;GO:0051015//actin filament binding	GO:0001544//initiation of primordial ovarian follicle growth;GO:0001547//antral ovarian follicle growth;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0008360//regulation of cell shape;GO:0008593//regulation of Notch signaling pathway;GO:0030728//ovulation;GO:0051764//actin crosslink formation;GO:0071711//basement membrane organization	--
ENSG00000148942	0.258	0.325	0.058	0.243	0.314	0.622	27	11	2	16	15	23	SLC5A12	solute carrier family 5 member 12 [Source:HGNC Symbol;Acc:HGNC:28750]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005343//organic acid:sodium symporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0035873//lactate transmembrane transport;GO:0055085//transmembrane transport;GO:1903825//organic acid transmembrane transport	--
ENSG00000148943	3.883	4.036	4.584	2.581	3.751	4.735	390	405	340	192	317	346	LIN7C	"lin-7 homolog C, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17789]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0097016//L27 domain binding	GO:0002011//morphogenesis of an epithelial sheet;GO:0006887//exocytosis;GO:0007269//neurotransmitter secretion;GO:0015031//protein transport;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000148948	0.133	0.241	0.171	0.105	0.05	0.058	9	15	6	5	2	2	LRRC4C	leucine rich repeat containing 4C [Source:HGNC Symbol;Acc:HGNC:29317]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction	ko04360//Axon guidance;ko04514//Cell adhesion molecules	K07523;K07523	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0098632//cell-cell adhesion mediator activity	GO:0050770//regulation of axonogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0099560//synaptic membrane adhesion	--
ENSG00000148950	3.164	3.738	2.925	5.443	2.936	3.224	31	37	23	34.48	23	28.75	IMMP1L	inner mitochondrial membrane peptidase subunit 1 [Source:HGNC Symbol;Acc:HGNC:26317]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K09647	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0042720//mitochondrial inner membrane peptidase complex	GO:0003674//molecular_function;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0008150//biological_process	--
ENSG00000148965	0	0	0	0	0	0	0	0	0	0	0	0	SAA4	"serum amyloid A4, constitutive [Source:HGNC Symbol;Acc:HGNC:10516]"	-	-	-	-	GO:0005576//extracellular region;GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006953//acute-phase response	--
ENSG00000148985	21.323	24.221	23.419	30.248	29.207	27.96	497	597	449	594	604	485	PGAP2	post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000149016	5.378	5.553	6.087	5.469	7.747	6.408	307.43	318.77	257.75	235.08	337.23	257.42	TUT1	"terminal uridylyl transferase 1, U6 snRNA-specific [Source:HGNC Symbol;Acc:HGNC:26184]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0017070//U6 snRNA binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0050265//RNA uridylyltransferase activity;GO:1990817//RNA adenylyltransferase activity	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0016180//snRNA processing;GO:0031123//RNA 3'-end processing;GO:0034477//U6 snRNA 3'-end processing;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000149021	0	0	0	0	0	0	0	0	0	0	0	0	SCGB1A1	secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0030141//secretory granule;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019834//phospholipase A2 inhibitor activity;GO:0097160//polychlorinated biphenyl binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007565//female pregnancy;GO:0007566//embryo implantation;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010193//response to ozone;GO:0032496//response to lipopolysaccharide;GO:0032689//negative regulation of interferon-gamma production;GO:0032696//negative regulation of interleukin-13 production;GO:0032713//negative regulation of interleukin-4 production;GO:0032714//negative regulation of interleukin-5 production;GO:0034021//response to silicon dioxide;GO:0034097//response to cytokine;GO:0042130//negative regulation of T cell proliferation;GO:0043086//negative regulation of catalytic activity;GO:0043488//regulation of mRNA stability;GO:0050727//regulation of inflammatory response;GO:0051384//response to glucocorticoid;GO:0071774//response to fibroblast growth factor	--
ENSG00000149043	0.387	0.297	0.571	0.353	0.088	0.103	7	8	8	7	2	2	SYT8	synaptotagmin 8 [Source:HGNC Symbol;Acc:HGNC:19264]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0070382//exocytic vesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0048306//calcium-dependent protein binding	GO:0006887//exocytosis;GO:0007340//acrosome reaction;GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0071277//cellular response to calcium ion	--
ENSG00000149050	1.44	1.442	0.972	0.5	1.074	1.704	120.7	95	49	31.71	72	71	ZNF214	zinc finger protein 214 [Source:HGNC Symbol;Acc:HGNC:13006]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000149054	0.248	0.089	0.216	0.19	0.202	0.346	11.3	5	10	9.29	10	17	ZNF215	zinc finger protein 215 [Source:HGNC Symbol;Acc:HGNC:13007]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000149084	91.254	79.993	80.655	75.079	74.952	81.78	4342	3946	2899	2733	3127	2924	HSD17B12	hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10251;K10251;K10251;K10251;K10251	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0009923//fatty acid elongase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0001968//fibronectin binding;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0016491//oxidoreductase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0050062//long-chain-fatty-acyl-CoA reductase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0102339//3-oxo-arachidoyl-CoA reductase activity;GO:0102340//3-oxo-behenoyl-CoA reductase activity;GO:0102341//3-oxo-lignoceroyl-CoA reductase activity;GO:0102342//3-oxo-cerotoyl-CoA reductase activity	GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process	--
ENSG00000149089	12.922	11.809	13.647	13.182	12.366	15.819	339	308	263	253	270	300	APIP	APAF1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17581]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K08964;K08964	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0046570//methylthioribulose 1-phosphate dehydratase activity;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0019284//L-methionine salvage from S-adenosylmethionine;GO:0019509//L-methionine salvage from methylthioadenosine;GO:0043066//negative regulation of apoptotic process;GO:0051289//protein homotetramerization;GO:0070269//pyroptosis;GO:0070372//regulation of ERK1 and ERK2 cascade	--
ENSG00000149090	0.319	0.1	0.24	0.027	0.209	0.028	18	5	10	1	10	1	PAMR1	peptidase domain containing associated with muscle regeneration 1 [Source:HGNC Symbol;Acc:HGNC:24554]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding	GO:0002252//immune effector process;GO:0006508//proteolysis;GO:0006955//immune response	--
ENSG00000149091	7.84	8.987	9.163	10.596	10.957	9.144	535	606	453	513	620	453	DGKZ	diacylglycerol kinase zeta [Source:HGNC Symbol;Acc:HGNC:2857]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0001727//lipid kinase activity;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	"GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030168//platelet activation;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0035556//intracellular signal transduction;GO:0045930//negative regulation of mitotic cell cycle;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0090216//positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity"	--
ENSG00000149100	73.642	70.198	63.148	73.094	64.125	76.112	1616	1635	1095	1243	1263	1226	EIF3M	eukaryotic translation initiation factor 3 subunit M [Source:HGNC Symbol;Acc:HGNC:24460]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000149115	34.01	33.754	41.89	35.641	37.721	42.955	2689	2802	2204	2133	2608	2376	TNKS1BP1	tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0030014//CCR4-NOT complex	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0071532//ankyrin repeat binding	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006302//double-strand break repair;GO:0007004//telomere maintenance via telomerase;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0031954//positive regulation of protein autophosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071479//cellular response to ionizing radiation	--
ENSG00000149124	0	0	0	0	0	0	0	0	0	0	0	0	GLYAT	glycine-N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:13734]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047961//glycine N-acyltransferase activity;GO:0047962//glycine N-benzoyltransferase activity	GO:0006544//glycine metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0032787//monocarboxylic acid metabolic process;GO:1901787//benzoyl-CoA metabolic process	--
ENSG00000149131	115.397	130.208	105.577	102.26	101.507	96.694	4248	4674	2810	2635	3136	2573	SERPING1	serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228]	Organismal Systems;Human Diseases	Immune system;Infectious disease: bacterial	ko04610//Complement and coagulation cascades;ko05133//Pertussis	K04001;K04001	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	"GO:0001869//negative regulation of complement activation, lectin pathway;GO:0002376//immune system process;GO:0006958//complement activation, classical pathway;GO:0007568//aging;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008015//blood circulation;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030193//regulation of blood coagulation;GO:0042730//fibrinolysis;GO:0045087//innate immune response;GO:0045916//negative regulation of complement activation"	--
ENSG00000149133	0	0	0	0	0	0	0	0	0	0	0	0	OR5F1	olfactory receptor family 5 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:8343]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000149136	38.752	36.983	32.531	32.095	26.87	32.165	1635	1689	1174	1029	1122	1084	SSRP1	structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0035101//FACT complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly;GO:0006974//cellular response to DNA damage stimulus;GO:1902275//regulation of chromatin organization	HMG
ENSG00000149150	0.671	0.749	0.747	1.02	0.557	1.143	32	28	27	35	23	23	SLC43A1	solute carrier family 43 member 1 [Source:HGNC Symbol;Acc:HGNC:9225]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0051956//negative regulation of amino acid transport;GO:0055085//transmembrane transport;GO:0060358//negative regulation of leucine import;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000149177	4.745	5.278	5.907	4.381	4.568	5.102	768	708	567	528	628	592	PTPRJ	protein tyrosine phosphatase receptor type J [Source:HGNC Symbol;Acc:HGNC:9673]	Human Diseases;Cellular Processes	Cancer: overview;Cellular community - eukaryotes	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04520//Adherens junction	K05698;K05698	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0051019//mitogen-activated protein kinase binding;GO:0070097//delta-catenin binding	GO:0006470//protein dephosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0016311//dephosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030155//regulation of cell adhesion;GO:0030183//B cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043116//negative regulation of vascular permeability;GO:0043407//negative regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045785//positive regulation of cell adhesion;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0051894//positive regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051898//negative regulation of protein kinase B signaling;GO:0060242//contact inhibition;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	--
ENSG00000149179	25.427	29.214	24.663	25.925	23.574	24.349	852	933	606	640	673	592	C11orf49	chromosome 11 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28720]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000149182	30.841	33.726	62.784	34.359	36.854	38.254	1534	1615	1275	1309	1440	1294	ARFGAP2	ADP ribosylation factor GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:13504]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12493	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle;GO:0050790//regulation of catalytic activity	--
ENSG00000149187	13.363	11.714	11.659	10.574	14.504	12.354	1597	1440	1118	999	1298	1076	CELF1	CUGBP Elav-like family member 1 [Source:HGNC Symbol;Acc:HGNC:2549]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0097356//perinucleolar compartment;GO:1990904//ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0031369//translation initiation factor binding;GO:0036002//pre-mRNA binding;GO:0042835//BRE binding"	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0007281//germ cell development;GO:0007286//spermatid development;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0009792//embryo development ending in birth or egg hatching;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0016246//RNA interference;GO:0016441//posttranscriptional gene silencing;GO:0021987//cerebral cortex development;GO:0040018//positive regulation of multicellular organism growth;GO:0043484//regulation of RNA splicing;GO:0050727//regulation of inflammatory response;GO:0061157//mRNA destabilization"	--
ENSG00000149196	10.713	11.349	10.296	12.321	9.037	12.164	258	275	189	213	186	214	HIKESHI	heat shock protein nuclear import factor hikeshi [Source:HGNC Symbol;Acc:HGNC:26938]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0030324//lung development;GO:0034605//cellular response to heat	--
ENSG00000149201	0.336	0.746	0.638	0.036	0.322	0.037	14	37	22	1	6	1	CCDC81	coiled-coil domain containing 81 [Source:HGNC Symbol;Acc:HGNC:26281]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000149212	98.107	72.165	76.136	61.468	68.204	75.307	19399	14370	11133	9006	11271	10851	SESN3	sestrin 3 [Source:HGNC Symbol;Acc:HGNC:23060]	Organismal Systems;Cellular Processes	Aging;Cell growth and death	ko04211//Longevity regulating pathway;ko04115//p53 signaling pathway	K10141;K10141	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031932//TORC2 complex;GO:0061700//GATOR2 complex	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016684//oxidoreductase activity, acting on peroxide as acceptor;GO:0070728//leucine binding"	GO:0016239//positive regulation of macroautophagy;GO:0032868//response to insulin;GO:0034198//cellular response to amino acid starvation;GO:0038203//TORC2 signaling;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0046626//regulation of insulin receptor signaling pathway;GO:0051896//regulation of protein kinase B signaling;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:1901031//regulation of response to reactive oxygen species;GO:1904262//negative regulation of TORC1 signaling;GO:1990253//cellular response to leucine starvation	--
ENSG00000149218	13.04	12.087	13.558	9.698	10.036	13.021	1258	1172	966	693	818	914	ENDOD1	endonuclease domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29129]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000149231	8.584	5.36	5.424	5.317	5.971	5.983	513	323	256	210	257	267	CCDC82	coiled-coil domain containing 82 [Source:HGNC Symbol;Acc:HGNC:26282]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000149243	0.257	0.288	0.261	0.738	0.922	0.398	8	9	6	17	25	9	KLHL35	kelch like family member 35 [Source:HGNC Symbol;Acc:HGNC:26597]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000149256	2.909	4.67	1.846	1.955	2.516	4.389	338	398	251	325	406	306	TENM4	teneurin transmembrane protein 4 [Source:HGNC Symbol;Acc:HGNC:29945]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0001702//gastrulation with mouth forming second;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0031641//regulation of myelination;GO:0031643//positive regulation of myelination;GO:0032289//central nervous system myelin formation;GO:0048666//neuron development;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0060038//cardiac muscle cell proliferation;GO:0060912//cardiac cell fate specification;GO:2000543//positive regulation of gastrulation	--
ENSG00000149257	182.005	193.65	189.188	203.666	199.06	168.193	7404	7996	5638	6071	6881	4988	SERPINH1	serpin family H member 1 [Source:HGNC Symbol;Acc:HGNC:1546]	-	-	-	-	GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix	GO:0003723//RNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0051082//unfolded protein binding	GO:0003433//chondrocyte development involved in endochondral bone morphogenesis;GO:0006986//response to unfolded protein;GO:0010951//negative regulation of endopeptidase activity;GO:0030199//collagen fibril organization;GO:0032964//collagen biosynthetic process;GO:0051604//protein maturation	--
ENSG00000149260	15.502	15.687	17.474	14.351	14.589	18.159	1252	1273	1087	910	1021	1061	CAPN5	calpain 5 [Source:HGNC Symbol;Acc:HGNC:1482]	-	-	-	-	GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007165//signal transduction	--
ENSG00000149262	7.249	7.795	7.324	5.648	6.52	7.105	428	485	323	253	350	298	INTS4	integrator complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:25048]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing	--
ENSG00000149269	17.843	19.56	17.612	16.029	15.027	14.353	1170	1167	861	670	857	718	PAK1	p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;Acc:HGNC:8590]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Signal transduction;Cell motility;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Development and regeneration;Immune system;Immune system;Immune system;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Signal transduction	ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04392//Hippo signaling pathway - multiple species	K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409;K04409	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0043015//gamma-tubulin binding;GO:0106310//protein serine kinase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006338//chromatin remodeling;GO:0006468//protein phosphorylation;GO:0006887//exocytosis;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0031116//positive regulation of microtubule polymerization;GO:0031532//actin cytoskeleton reorganization;GO:0032956//regulation of actin cytoskeleton organization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042060//wound healing;GO:0043408//regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0046777//protein autophosphorylation;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048812//neuron projection morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0090063//positive regulation of microtubule nucleation	--
ENSG00000149273	389.434	394.733	391.683	479.591	401.423	404.775	6955	6978	5264	6588	5941	5334	RPS3	ribosomal protein S3 [Source:HGNC Symbol;Acc:HGNC:10420]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Translation	ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko03010//Ribosome	K02985;K02985;K02985;K02985	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005819//spindle;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0032587//ruffle membrane;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0071159//NF-kappaB complex;GO:0072686//mitotic spindle;GO:1990904//ribonucleoprotein complex	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0016829//lyase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding;GO:0032357//oxidized purine DNA binding;GO:0032358//oxidized pyrimidine DNA binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0044877//protein-containing complex binding;GO:0051018//protein kinase A binding;GO:0051536//iron-sulfur cluster binding;GO:0051879//Hsp90 protein binding;GO:0070181//small ribosomal subunit rRNA binding;GO:0097100//supercoiled DNA binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0140297//DNA-binding transcription factor binding	GO:0002181//cytoplasmic translation;GO:0006281//DNA repair;GO:0006396//RNA processing;GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0010628//positive regulation of gene expression;GO:0017148//negative regulation of translation;GO:0031116//positive regulation of microtubule polymerization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031397//negative regulation of protein ubiquitination;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0032743//positive regulation of interleukin-2 production;GO:0034614//cellular response to reactive oxygen species;GO:0042104//positive regulation of activated T cell proliferation;GO:0042981//regulation of apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0045738//negative regulation of DNA repair;GO:0045739//positive regulation of DNA repair;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0061481//response to TNF agonist;GO:0070301//cellular response to hydrogen peroxide;GO:0071356//cellular response to tumor necrosis factor;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902546//positive regulation of DNA N-glycosylase activity;GO:1905053//positive regulation of base-excision repair;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001272//positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	--
ENSG00000149289	3.959	3.178	3.054	3.55	3.518	3.188	633	460	364	301	353	367	ZC3H12C	zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003674//molecular_function;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0008150//biological_process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000149292	8.468	10.708	8.618	9.291	9.886	9.089	337	380	264	242	292	238	TTC12	tetratricopeptide repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:23700]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0005515//protein binding	GO:0007288//sperm axoneme assembly;GO:0030030//cell projection organization;GO:0070286//axonemal dynein complex assembly	--
ENSG00000149294	1.341	1.124	1.494	1.343	2.124	1.442	133	116	63	87	149	92	NCAM1	neural cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:7656]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signaling molecules and interaction	ko05020//Prion disease;ko04514//Cell adhesion molecules	K06491;K06491	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0043005//neuron projection;GO:0062023//collagen-containing extracellular matrix	GO:0001618//virus receptor activity;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0046718//viral entry into host cell;GO:0071679//commissural neuron axon guidance;GO:2001260//regulation of semaphorin-plexin signaling pathway	--
ENSG00000149295	0.106	0.019	0.116	0.106	0	0.027	5	1	5	4	0	1	DRD2	dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases	Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Signal transduction;Substance dependence;Nervous system;Cellular community - eukaryotes;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko05012//Parkinson disease;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04540//Gap junction;ko05030//Cocaine addiction	K04145;K04145;K04145;K04145;K04145;K04145;K04145;K04145	GO:0000139//Golgi membrane;GO:0001669//acrosomal vesicle;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0036126//sperm flagellum;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium;GO:0098691//dopaminergic synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	"GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930//G protein-coupled receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0035240//dopamine binding;GO:0035255//ionotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0097159//organic cyclic compound binding;GO:1901363//heterocyclic compound binding"	"GO:0001659//temperature homeostasis;GO:0001666//response to hypoxia;GO:0001933//negative regulation of protein phosphorylation;GO:0001963//synaptic transmission, dopaminergic;GO:0001964//startle response;GO:0001975//response to amphetamine;GO:0001976//nervous system process involved in regulation of systemic arterial blood pressure;GO:0002027//regulation of heart rate;GO:0002028//regulation of sodium ion transport;GO:0002031//G protein-coupled receptor internalization;GO:0002052//positive regulation of neuroblast proliferation;GO:0002092//positive regulation of receptor internalization;GO:0006874//cellular calcium ion homeostasis;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0007608//sensory perception of smell;GO:0007616//long-term memory;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0007628//adult walking behavior;GO:0007631//feeding behavior;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0008306//associative learning;GO:0008542//visual learning;GO:0009410//response to xenobiotic stimulus;GO:0009416//response to light stimulus;GO:0009636//response to toxic substance;GO:0010039//response to iron ion;GO:0014059//regulation of dopamine secretion;GO:0014854//response to inactivity;GO:0016055//Wnt signaling pathway;GO:0021756//striatum development;GO:0021769//orbitofrontal cortex development;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0021984//adenohypophysis development;GO:0030336//negative regulation of cell migration;GO:0030432//peristalsis;GO:0030534//adult behavior;GO:0030900//forebrain development;GO:0031223//auditory behavior;GO:0032147//activation of protein kinase activity;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0032467//positive regulation of cytokinesis;GO:0032922//circadian regulation of gene expression;GO:0033602//negative regulation of dopamine secretion;GO:0034776//response to histamine;GO:0035094//response to nicotine;GO:0035556//intracellular signal transduction;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0040018//positive regulation of multicellular organism growth;GO:0042220//response to cocaine;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0042417//dopamine metabolic process;GO:0042756//drinking behavior;GO:0043266//regulation of potassium ion transport;GO:0043278//response to morphine;GO:0043408//regulation of MAPK cascade;GO:0043473//pigmentation;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0045471//response to ethanol;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0045776//negative regulation of blood pressure;GO:0045824//negative regulation of innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046676//negative regulation of insulin secretion;GO:0046717//acid secretion;GO:0048148//behavioral response to cocaine;GO:0048149//behavioral response to ethanol;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048678//response to axon injury;GO:0048755//branching morphogenesis of a nerve;GO:0050482//arachidonic acid secretion;GO:0050709//negative regulation of protein secretion;GO:0050769//positive regulation of neurogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050805//negative regulation of synaptic transmission;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051580//regulation of neurotransmitter uptake;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0051823//regulation of synapse structural plasticity;GO:0051898//negative regulation of protein kinase B signaling;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060124//positive regulation of growth hormone secretion;GO:0060134//prepulse inhibition;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0060548//negative regulation of cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0090325//regulation of locomotion involved in locomotory behavior;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:1900168//positive regulation of glial cell-derived neurotrophic factor production;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1903530//regulation of secretion by cell;GO:1990384//hyaloid vascular plexus regression;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000149300	0.306	0.695	0.65	1.061	0.775	1.2	7	16	11	18	15	20	C11orf52	chromosome 11 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:30531]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000149305	0	0	0.015	0	0.067	0	0	0	1	0	2	0	HTR3B	5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298]	Organismal Systems;Organismal Systems	Nervous system;Sensory system	ko04726//Serotonergic synapse;ko04742//Taste transduction	K04819;K04819	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1904602//serotonin-activated cation-selective channel complex	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0015276//ligand-gated ion channel activity;GO:0022850//serotonin-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000149308	2.421	3.006	1.674	1.752	2.044	1.984	307	299	140	114	158	148	NPAT	"nuclear protein, coactivator of histone transcription [Source:HGNC Symbol;Acc:HGNC:7896]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0097504//Gemini of coiled bodies	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0001701//in utero embryonic development;GO:0007049//cell cycle;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000149311	5.644	2.344	2.662	1.714	2.211	2.282	1149	573	439	334	483	390	ATM	ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Genetic Information Processing	Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cell growth and death;Cell growth and death;Signal transduction;Cell growth and death;Drug resistance: antineoplastic;Cell growth and death;Replication and repair	ko05165//Human papillomavirus infection;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04218//Cellular senescence;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko03440//Homologous recombination	K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728;K04728	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005782//peroxisomal matrix;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1990391//DNA repair complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004677//DNA-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding;GO:0106310//protein serine kinase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0001541//ovarian follicle development;GO:0001666//response to hypoxia;GO:0001756//somitogenesis;GO:0002331//pre-B cell allelic exclusion;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006950//response to stress;GO:0006974//cellular response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0007143//female meiotic nuclear division;GO:0007165//signal transduction;GO:0007292//female gamete generation;GO:0007420//brain development;GO:0007507//heart development;GO:0008340//determination of adult lifespan;GO:0008585//female gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009791//post-embryonic development;GO:0010212//response to ionizing radiation;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0030889//negative regulation of B cell proliferation;GO:0032210//regulation of telomere maintenance via telomerase;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0033129//positive regulation of histone phosphorylation;GO:0033151//V(D)J recombination;GO:0035264//multicellular organism growth;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0036289//peptidyl-serine autophosphorylation;GO:0042159//lipoprotein catabolic process;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043525//positive regulation of neuron apoptotic process;GO:0045141//meiotic telomere clustering;GO:0045785//positive regulation of cell adhesion;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0048538//thymus development;GO:0048599//oocyte development;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0071044//histone mRNA catabolic process;GO:0071300//cellular response to retinoic acid;GO:0071480//cellular response to gamma radiation;GO:0071481//cellular response to X-ray;GO:0071500//cellular response to nitrosative stress;GO:0080135//regulation of cellular response to stress;GO:0090398//cellular senescence;GO:0090399//replicative senescence;GO:0097694//establishment of RNA localization to telomere;GO:0097695//establishment of protein-containing complex localization to telomere;GO:1900034//regulation of cellular response to heat;GO:1901216//positive regulation of neuron death;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1903626//positive regulation of DNA catabolic process;GO:1903978//regulation of microglial cell activation;GO:1904262//negative regulation of TORC1 signaling;GO:1904354//negative regulation of telomere capping;GO:1904358//positive regulation of telomere maintenance via telomere lengthening;GO:1904884//positive regulation of telomerase catalytic core complex assembly;GO:1905843//regulation of cellular response to gamma radiation;GO:2000112//regulation of cellular macromolecule biosynthetic process;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000149313	27.363	25.143	22.035	19.768	20.739	20.826	1514	1422	889	809	970	838	AASDHPPT	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Source:HGNC Symbol;Acc:HGNC:14235]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K06133;K06133	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008897//holo-[acyl-carrier-protein] synthase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0009258//10-formyltetrahydrofolate catabolic process;GO:0015939//pantothenate metabolic process;GO:0018215//protein phosphopantetheinylation;GO:0019878//lysine biosynthetic process via aminoadipic acid;GO:0051604//protein maturation	--
ENSG00000149328	13.735	17.53	14.29	13.979	15.117	14.537	898	1152	690	677	835	692	GLB1L2	galactosidase beta 1 like 2 [Source:HGNC Symbol;Acc:HGNC:25129]	-	-	-	-	GO:0005576//extracellular region;GO:0005773//vacuole	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004565//beta-galactosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000149346	0.836	0.887	0.647	0.602	0.688	0.722	105	112	60	56	73	66	SLX4IP	SLX4 interacting protein [Source:HGNC Symbol;Acc:HGNC:16225]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000149357	57.468	59.576	66.771	70.565	65.98	61.876	1297	1351	1110	1181	1257	1014	LAMTOR1	"late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 [Source:HGNC Symbol;Acc:HGNC:26068]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20397	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0071986//Ragulator complex;GO:0101003//ficolin-1-rich granule membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0051020//GTPase binding;GO:0060090//molecular adaptor activity	GO:0001558//regulation of cell growth;GO:0001919//regulation of receptor recycling;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0010872//regulation of cholesterol esterification;GO:0010874//regulation of cholesterol efflux;GO:0016197//endosomal transport;GO:0032008//positive regulation of TOR signaling;GO:0032418//lysosome localization;GO:0034613//cellular protein localization;GO:0038202//TORC1 signaling;GO:0042632//cholesterol homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0050790//regulation of catalytic activity;GO:0060620//regulation of cholesterol import;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000149380	0.834	0.787	0.61	0.66	0.456	0.882	39	37	21	23	18	30	P4HA3	prolyl 4-hydroxylase subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:30135]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00472;K00472	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	"GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0019511//peptidyl-proline hydroxylation	--
ENSG00000149403	1.553	1.334	1.348	0.634	0.412	0.779	145	124	92	47	42	47	GRIK4	glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04724//Glutamatergic synapse	K05204;K05204	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity;GO:0038023//signaling receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0050804//modulation of chemical synaptic transmission;GO:0060078//regulation of postsynaptic membrane potential"	--
ENSG00000149418	0.029	0.044	0	0.158	0.242	0.08	2	3	0	8	14	4	ST14	ST14 transmembrane serine protease matriptase [Source:HGNC Symbol;Acc:HGNC:11344]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K08670	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0019897//extrinsic component of plasma membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001843//neural tube closure;GO:0006508//proteolysis;GO:0030216//keratinocyte differentiation;GO:0060672//epithelial cell morphogenesis involved in placental branching	--
ENSG00000149428	46.994	47.981	46.624	48.5	54.915	45.471	4311	4414	3141	3295	4244	3045	HYOU1	hypoxia up-regulated 1 [Source:HGNC Symbol;Acc:HGNC:16931]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09486	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005790//smooth endoplasmic reticulum;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0034663//endoplasmic reticulum chaperone complex;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0002931//response to ischemia;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0034976//response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0071456//cellular response to hypoxia;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:1903382//negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	--
ENSG00000149435	0	0	0	0	0	0	0	0	0	0	0	0	GGTLC1	gamma-glutamyltransferase light chain 1 [Source:HGNC Symbol;Acc:HGNC:16437]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0036374//glutathione hydrolase activity	GO:0006508//proteolysis;GO:0006751//glutathione catabolic process;GO:0008150//biological_process;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000149451	0.899	0.953	1.149	1.729	1.859	1.683	68	71	62	92	115	89	ADAM33	ADAM metallopeptidase domain 33 [Source:HGNC Symbol;Acc:HGNC:15478]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000149452	91.296	92.91	118.649	149.323	153.997	127.799	3894	3968	3682	4676	5475	3942	SLC22A8	solute carrier family 22 member 8 [Source:HGNC Symbol;Acc:HGNC:10972]	Organismal Systems	Digestive system	ko04976//Bile secretion	K08205	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0098590//plasma membrane region	GO:0005452//inorganic anion exchanger activity;GO:0015075//ion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0009636//response to toxic substance;GO:0015698//inorganic anion transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000149474	10.382	11.293	10.759	11.268	11.152	10.344	732.99	814.26	558.72	591.66	654.9	526.03	KAT14	lysine acetyltransferase 14 [Source:HGNC Symbol;Acc:HGNC:15904]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0030274//LIM domain binding	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0031063//regulation of histone deacetylation;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000149476	9.14	9.482	9.413	10.331	9.656	8.99	489.08	540.71	337.59	415.53	490.81	321.32	TKFC	triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552]	Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Immune system;Lipid metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04622//RIG-I-like receptor signaling pathway;ko00561//Glycerolipid metabolism;ko00051//Fructose and mannose metabolism	K00863;K00863;K00863;K00863;K00863	GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004371//glycerone kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0034012//FAD-AMP lyase (cyclizing) activity;GO:0046872//metal ion binding;GO:0050354//triokinase activity	GO:0005975//carbohydrate metabolic process;GO:0006071//glycerol metabolic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0019563//glycerol catabolic process;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0044262//cellular carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0045088//regulation of innate immune response;GO:0046835//carbohydrate phosphorylation	--
ENSG00000149480	18.842	20.933	21.623	20.178	19.748	22.495	1104	1243	987	898	980	986	MTA2	metastasis associated 1 family member 2 [Source:HGNC Symbol;Acc:HGNC:7411]	-	-	-	-	"GO:0000118//histone deacetylase complex;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016020//membrane;GO:0016581//NuRD complex;GO:0032991//protein-containing complex"	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006333//chromatin assembly or disassembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0010762//regulation of fibroblast migration;GO:0016575//histone deacetylation;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000736//regulation of stem cell differentiation"	zf-GATA
ENSG00000149483	14.529	12.564	12.384	14.128	12.172	13.241	465.77	395.43	277.99	340.5	327.95	314.93	TMEM138	transmembrane protein 138 [Source:HGNC Symbol;Acc:HGNC:26944]	-	-	-	-	GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	-	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000149485	85.803	83.412	82.649	84.369	85.351	98.076	7138.76	6919.08	5080	5380	6242	5952	FADS1	fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko01040//Biosynthesis of unsaturated fatty acids	K10224;K10224;K10224	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0000248//C-5 sterol desaturase activity;GO:0016213//linoleoyl-CoA desaturase activity;GO:0016491//oxidoreductase activity;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;GO:0045485//omega-6 fatty acid desaturase activity;GO:0062076//acyl-CoA delta5-desaturase activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0007267//cell-cell signaling;GO:0008654//phospholipid biosynthetic process;GO:0009267//cellular response to starvation;GO:0036109//alpha-linolenic acid metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0045595//regulation of cell differentiation;GO:0046456//icosanoid biosynthetic process"	--
ENSG00000149488	0.01	0.029	0	0.026	0.023	0.027	1	3	0	2	2	2	TMC2	transmembrane channel like 2 [Source:HGNC Symbol;Acc:HGNC:16527]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032426//stereocilium tip	GO:0003674//molecular_function;GO:0005245//voltage-gated calcium channel activity;GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060005//vestibular reflex;GO:0070588//calcium ion transmembrane transport;GO:1903169//regulation of calcium ion transmembrane transport	--
ENSG00000149489	6.824	6.251	6.442	6.038	6.707	5.912	132.73	123.43	94.33	94.87	104.42	87.55	ROM1	retinal outer segment membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:10254]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0010468//regulation of gene expression;GO:0035845//photoreceptor cell outer segment organization;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization;GO:0060041//retina development in camera-type eye;GO:0060042//retina morphogenesis in camera-type eye;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0061298//retina vasculature development in camera-type eye;GO:1903546//protein localization to photoreceptor outer segment	--
ENSG00000149499	12.839	13.926	14.588	14.832	15.139	15.144	818.27	878.57	663.67	708.13	821.58	655.45	EML3	EMAP like 3 [Source:HGNC Symbol;Acc:HGNC:26666]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0072686//mitotic spindle;GO:1990498//mitotic spindle microtubule	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0051301//cell division;GO:1901673//regulation of mitotic spindle assembly	--
ENSG00000149503	3.928	3.862	3.881	2.86	4.384	3.102	300	288	235	169	297	183	INCENP	inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0000801//central element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0010369//chromocenter;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body;GO:0030496//midbody;GO:0032133//chromosome passenger complex;GO:0032991//protein-containing complex;GO:1990385//meiotic spindle midzone"	GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0016572//histone phosphorylation;GO:0051256//mitotic spindle midzone assembly;GO:0051257//meiotic spindle midzone assembly;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1901970//positive regulation of mitotic sister chromatid separation;GO:1902412//regulation of mitotic cytokinesis;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1903490//positive regulation of mitotic cytokinesis	--
ENSG00000149506	0	0	0	0	0	0	0	0	0	0	0	0	ZP1	zona pellucida glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:13187]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035805//egg coat;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0032190//acrosin binding;GO:0035804//structural constituent of egg coat	GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0060468//prevention of polyspermy	--
ENSG00000149507	0	0	0	0	0	0	0	0	0	0	0	0	OOSP2	oocyte secreted protein 2 [Source:HGNC Symbol;Acc:HGNC:26699]	-	-	-	-	GO:0005576//extracellular region;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000149516	0	0	0	0	0	0	0	0	0	0	0	0	MS4A3	membrane spanning 4-domains A3 [Source:HGNC Symbol;Acc:HGNC:7317]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway;GO:0051726//regulation of cell cycle	--
ENSG00000149527	0.4	0.502	0.505	0.594	0.554	0.866	36	51	38	43	47	54	PLCH2	phospholipase C eta 2 [Source:HGNC Symbol;Acc:HGNC:29037]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism	K19006;K19006	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005509//calcium ion binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000149532	25.322	24.295	20.928	23.453	24.33	24.055	1351	1530	1016	1113	1231	1085	CPSF7	cleavage and polyadenylation specific factor 7 [Source:HGNC Symbol;Acc:HGNC:30098]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14398	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005849//mRNA cleavage factor complex;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0031124//mRNA 3'-end processing;GO:0051262//protein tetramerization;GO:0051290//protein heterotetramerization;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0110104//mRNA alternative polyadenylation;GO:1990120//messenger ribonucleoprotein complex assembly	--
ENSG00000149534	0	0	0	0	0	0	0	0	0	0	0	0	MS4A2	membrane spanning 4-domains A2 [Source:HGNC Symbol;Acc:HGNC:7316]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Immune system;Signal transduction;Immune disease	ko04072//Phospholipase D signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04071//Sphingolipid signaling pathway;ko05310//Asthma	K08090;K08090;K08090;K08090	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032998//Fc-epsilon receptor I complex	GO:0005515//protein binding;GO:0019863//IgE binding	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway	--
ENSG00000149541	33.736	34.464	36.419	48.285	40.772	42.875	1021	1044	811	1087	1030	941	B3GAT3	"beta-1,3-glucuronyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:923]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K10158;K10158;K10158	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0072542//protein phosphatase activator activity	GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0043085//positive regulation of catalytic activity;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0090316//positive regulation of intracellular protein transport	--
ENSG00000149547	67.016	67.098	63.267	86.252	74.298	77.17	2655	2609	1889	2489	2389	2141	EI24	EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10134	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0061676//importin-alpha family protein binding	GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0016236//macroautophagy;GO:0030308//negative regulation of cell growth	--
ENSG00000149548	0.531	0.503	0.383	0.205	0.296	0.614	42	40	23	12	20	36	CCDC15	coiled-coil domain containing 15 [Source:HGNC Symbol;Acc:HGNC:25798]	-	-	-	-	GO:0005813//centrosome	-	-	--
ENSG00000149554	2.258	1.847	2.963	2.037	1.567	1.676	138	118	112	77	72	73	CHEK1	checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes	Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cell growth and death;Cell growth and death;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko04218//Cellular senescence;ko04110//Cell cycle;ko04115//p53 signaling pathway	K02216;K02216;K02216;K02216;K02216;K02216	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0035402//histone kinase activity (H3-T11 specific);GO:0106310//protein serine kinase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000086//G2/M transition of mitotic cell cycle;GO:0001833//inner cell mass cell proliferation;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0006997//nucleus organization;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010468//regulation of gene expression;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010767//regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0035407//histone H3-T11 phosphorylation;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045787//positive regulation of cell cycle;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045839//negative regulation of mitotic nuclear division;GO:0046602//regulation of mitotic centrosome separation;GO:0070317//negative regulation of G0 to G1 transition;GO:0071260//cellular response to mechanical stimulus;GO:0071310//cellular response to organic substance;GO:0071313//cellular response to caffeine;GO:0090399//replicative senescence;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902742//apoptotic process involved in development;GO:2000279//negative regulation of DNA biosynthetic process;GO:2000615//regulation of histone H3-K9 acetylation"	--
ENSG00000149557	12.752	12.883	16.417	15.665	13.456	18.139	549	549	473	506	515	546	FEZ1	fasciculation and elongation protein zeta 1 [Source:HGNC Symbol;Acc:HGNC:3659]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:0047485//protein N-terminus binding	GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0010976//positive regulation of neuron projection development;GO:0021766//hippocampus development;GO:0030010//establishment of cell polarity;GO:0045666//positive regulation of neuron differentiation;GO:0051654//establishment of mitochondrion localization;GO:0061881//positive regulation of anterograde axonal transport of mitochondrion;GO:0070584//mitochondrion morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000149564	0	0.026	0	0	0.062	0.072	0	1	0	0	2	2	ESAM	endothelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:17474]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06787;K06787	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030833//regulation of actin filament polymerization;GO:0034613//cellular protein localization;GO:0035633//maintenance of blood-brain barrier;GO:0070830//bicellular tight junction assembly;GO:0098609//cell-cell adhesion;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000149571	0.114	0.019	0	0.026	0.03	0.098	8	1	0	1	2	5	KIRREL3	kirre like nephrin family adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:23204]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043198//dendritic shaft	GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding	GO:0001764//neuron migration;GO:0002121//inter-male aggressive behavior;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0021740//principal sensory nucleus of trigeminal nerve development;GO:0021766//hippocampus development;GO:0030097//hemopoiesis;GO:0048812//neuron projection morphogenesis;GO:0072102//glomerulus morphogenesis;GO:0098609//cell-cell adhesion	--
ENSG00000149573	16.04	13.408	13.686	9.525	11.479	16.069	760	647	460	316	450	522	MPZL2	myelin protein zero like 2 [Source:HGNC Symbol;Acc:HGNC:3496]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653//anatomical structure morphogenesis;GO:0098609//cell-cell adhesion	--
ENSG00000149575	6.113	6.898	6.585	8.029	6.572	7.555	626	710	498	609	566	544	SCN2B	sodium voltage-gated channel beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:10589]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005272//sodium channel activity;GO:0017080//sodium channel regulator activity;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0009408//response to heat;GO:0010467//gene expression;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0046684//response to pyrethroid;GO:0060048//cardiac muscle contraction;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0061337//cardiac conduction;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000149577	9.815	11.103	11.294	12.709	10.73	12.802	803	927	681	793	762	700	SIDT2	SID1 transmembrane family member 2 [Source:HGNC Symbol;Acc:HGNC:24272]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0035612//AP-2 adaptor complex binding;GO:0035650//AP-1 adaptor complex binding;GO:0051032//nucleic acid transmembrane transporter activity;GO:0051033//RNA transmembrane transporter activity	GO:0000902//cell morphogenesis;GO:0003323//type B pancreatic cell development;GO:0006401//RNA catabolic process;GO:0009749//response to glucose;GO:0042593//glucose homeostasis;GO:0044342//type B pancreatic cell proliferation;GO:0050658//RNA transport;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000149582	21.814	20.912	22.552	22.481	24.877	21.97	805	798	651	644	784	647	TMEM25	transmembrane protein 25 [Source:HGNC Symbol;Acc:HGNC:25890]	-	-	-	-	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0031647//regulation of protein stability;GO:0090394//negative regulation of excitatory postsynaptic potential	--
ENSG00000149591	155.142	161.504	115.915	69.134	76.56	68.836	5600.89	5929.25	3141.96	1773.01	2263.94	1735.95	TAGLN	transgelin [Source:HGNC Symbol;Acc:HGNC:11553]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007517//muscle organ development;GO:0030855//epithelial cell differentiation	--
ENSG00000149596	3.37	3.485	2.708	4.589	4.62	4.752	597	636	375	631	755	632	JPH2	junctophilin 2 [Source:HGNC Symbol;Acc:HGNC:14202]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030314//junctional membrane complex;GO:0033017//sarcoplasmic reticulum membrane	"GO:0001786//phosphatidylserine binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0055024//regulation of cardiac muscle tissue development;GO:0055074//calcium ion homeostasis;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0060402//calcium ion transport into cytosol	--
ENSG00000149599	5.345	6.046	5.832	7.952	6.742	6.772	136	158	112	151	145	127	DUSP15	dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042127//regulation of cell population proliferation;GO:0046330//positive regulation of JNK cascade;GO:0048713//regulation of oligodendrocyte differentiation	--
ENSG00000149600	27.295	28.198	31.266	27.963	26.872	29.51	771.89	804.91	654.86	584.88	643.36	603.09	COMMD7	COMM domain containing 7 [Source:HGNC Symbol;Acc:HGNC:16223]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0051059//NF-kappaB binding	"GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000149609	0	0	0.25	0	0	0	0	0	2	0	0	0	C20orf144	chromosome 20 open reading frame 144 [Source:HGNC Symbol;Acc:HGNC:16137]	-	-	-	-	-	-	-	--
ENSG00000149633	0.179	0.433	0.207	0.147	0.009	0.155	16	24	9	3	1	6	KIAA1755	KIAA1755 [Source:HGNC Symbol;Acc:HGNC:29372]	-	-	-	-	-	-	-	--
ENSG00000149634	0.325	0.711	0.528	1.053	0.385	0.357	5	11	6	12	5	4	SPATA25	spermatogenesis associated 25 [Source:HGNC Symbol;Acc:HGNC:16158]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000149635	0	0.09	0	0	0	0	0	4	0	0	0	0	OCSTAMP	osteoclast stimulatory transmembrane protein [Source:HGNC Symbol;Acc:HGNC:16116]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0030154//cell differentiation;GO:0034241//positive regulation of macrophage fusion;GO:0045672//positive regulation of osteoclast differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:0071391//cellular response to estrogen stimulus;GO:0072674//multinuclear osteoclast differentiation;GO:0090290//positive regulation of osteoclast proliferation	--
ENSG00000149636	5.05	4.556	4.7	3.546	3.144	2.702	204	201	156	111	118	80	DSN1	DSN1 component of MIS12 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:16165]	-	-	-	-	"GO:0000444//MIS12/MIND type complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000818//nuclear MIS12/MIND complex;GO:0001650//fibrillar center;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031617//NMS complex;GO:0035578//azurophil granule lumen"	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0051301//cell division	--
ENSG00000149639	8.325	7.462	8.686	8.51	9.942	10.425	2429	2212	1892	1859	2477	2237	SOGA1	"suppressor of glucose, autophagy associated 1 [Source:HGNC Symbol;Acc:HGNC:16111]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008286//insulin receptor signaling pathway;GO:0010506//regulation of autophagy;GO:0045721//negative regulation of gluconeogenesis	--
ENSG00000149646	0.101	0.495	0.58	1.128	0.695	0.678	3	8.33	6.81	12.81	8.98	7.74	CNBD2	cyclic nucleotide binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16145]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0030552//cAMP binding	GO:0007283//spermatogenesis	--
ENSG00000149651	0	0	0	0	0	0	0	0	0	0	0	0	SPINT4	"serine peptidase inhibitor, Kunitz type 4 [Source:HGNC Symbol;Acc:HGNC:16130]"	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000149654	0.074	0.123	0.067	0.017	0.117	0.017	6	10	4	1	8	1	CDH22	cadherin 22 [Source:HGNC Symbol;Acc:HGNC:13251]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007420//brain development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000149657	20.524	17.788	20.606	20.953	19.512	21.653	800	762	640	631	657	677	LSM14B	LSM family member 14B [Source:HGNC Symbol;Acc:HGNC:15887]	-	-	-	-	-	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006417//regulation of translation	--
ENSG00000149658	20.482	21.718	23.75	21.399	20.738	23.457	1316	1396	1103	943	1130	1078	YTHDF1	YTH N6-methyladenosine RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15867]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:1990247//N6-methyladenosine-containing RNA binding	GO:0002376//immune system process;GO:0002577//regulation of antigen processing and presentation;GO:0007612//learning;GO:0007613//memory;GO:0034063//stress granule assembly;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation;GO:0045948//positive regulation of translational initiation;GO:0061157//mRNA destabilization;GO:0070925//organelle assembly;GO:1900271//regulation of long-term synaptic potentiation;GO:1902667//regulation of axon guidance	--
ENSG00000149679	4.282	4.209	4.072	4.25	3.56	4.151	336	332	236	247	236	237	CABLES2	Cdk5 and Abl enzyme substrate 2 [Source:HGNC Symbol;Acc:HGNC:16143]	-	-	-	-	-	-	GO:0007049//cell cycle;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000149716	1.981	3.251	3.727	4.18	2.393	5.078	82	112.02	76	118	86.02	106	LTO1	LTO1 maturation factor of ABCE1 [Source:HGNC Symbol;Acc:HGNC:17589]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0005515//protein binding	GO:0000723//telomere maintenance;GO:0006413//translational initiation;GO:0042273//ribosomal large subunit biogenesis;GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000149735	0	0	0	0	0	0	0	0	0	0	0	0	GPHA2	glycoprotein hormone subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:18054]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway	K25483;K25483	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031531//thyrotropin-releasing hormone receptor binding;GO:0046982//protein heterodimerization activity;GO:0051427//hormone receptor binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000149742	0.041	0	0	0	0	0	2	0	0	0	0	0	SLC22A9	solute carrier family 22 member 9 [Source:HGNC Symbol;Acc:HGNC:16261]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0015301//anion:anion antiporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015636//short-chain fatty acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0009914//hormone transport;GO:0015711//organic anion transport;GO:0015912//short-chain fatty acid transport;GO:0015913//short-chain fatty acid import;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport	--
ENSG00000149743	9.071	11.058	10.514	11.166	10.304	9.799	159	206	145	151	158	130	TRPT1	tRNA phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:20316]	-	-	-	-	-	GO:0000215//tRNA 2'-phosphotransferase activity;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016740//transferase activity	"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0008033//tRNA processing;GO:0008150//biological_process;GO:0045859//regulation of protein kinase activity"	--
ENSG00000149761	15.948	17.32	16.51	18.804	17.154	17.199	348	377	264	303	310	274.13	NUDT22	nudix hydrolase 22 [Source:HGNC Symbol;Acc:HGNC:28189]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0008768//UDP-sugar diphosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0052751//GDP-mannose hydrolase activity	-	--
ENSG00000149781	0	0.019	0.072	0	0.127	0.053	0	1	1	0	3	2	FERMT3	FERM domain containing kindlin 3 [Source:HGNC Symbol;Acc:HGNC:23151]	Organismal Systems	Immune system	ko04611//Platelet activation	K17084	GO:0002102//podosome;GO:0005576//extracellular region;GO:0016020//membrane;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0031093//platelet alpha granule lumen;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030335//positive regulation of cell migration;GO:0033622//integrin activation;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0034446//substrate adhesion-dependent cell spreading;GO:0070527//platelet aggregation	--
ENSG00000149782	3.249	3.56	3.549	2.809	3.52	3.463	287	316	231	183	267	219	PLCB3	phospholipase C beta 3 [Source:HGNC Symbol;Acc:HGNC:9056]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Immune system;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Immune system;Immune system;Infectious disease: parasitic;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Sensory system;Digestive system;Endocrine system;Carbohydrate metabolism;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system;Excretory system;Digestive system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko00562//Inositol phosphate metabolism;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption"	K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0099524//postsynaptic cytosol	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0045296//cadherin binding	GO:0003073//regulation of systemic arterial blood pressure;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0046488//phosphatidylinositol metabolic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000149792	28.21	32.355	32.413	30.262	31.631	33.948	1185	1353	1006	942	1123	1038	MRPL49	mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000149798	2.39	2.277	2.28	4.851	4.988	4.892	97.33	93.19	68.55	146.32	171.6	144.93	CDC42EP2	CDC42 effector protein 2 [Source:HGNC Symbol;Acc:HGNC:16263]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0045335//phagocytic vesicle	GO:0001515//opioid peptide activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007015//actin filament organization;GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0031334//positive regulation of protein-containing complex assembly;GO:0050790//regulation of catalytic activity;GO:0071346//cellular response to interferon-gamma	--
ENSG00000149806	195.328	200.189	221.986	233.483	200.765	171.949	2052	2115	1724	1817	1782	1314	FAU	FAU ubiquitin like and ribosomal protein S30 fusion [Source:HGNC Symbol;Acc:HGNC:3597]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02983;K02983	GO:0005575//cellular_component;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0002227//innate immune response in mucosa;GO:0006412//translation;GO:0008150//biological_process;GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000149809	42.813	44.203	49.992	62.177	53.17	45.706	1222	1321	1084	1355	1368	1002	TM7SF2	transmembrane 7 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11863]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K00222;K00222	GO:0005637//nuclear inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050613//delta14-sterol reductase activity;GO:0050661//NADP binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process	--
ENSG00000149823	63.331	47.269	76.566	106.015	109.938	70.636	2245	2223	1790	2291	2321	2012	VPS51	VPS51 subunit of GARP complex [Source:HGNC Symbol;Acc:HGNC:1172]	-	-	-	-	GO:0000938//GARP complex;GO:0005730//nucleolus;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:1990745//EARP complex	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0006869//lipid transport;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0007041//lysosomal transport;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi;GO:0048193//Golgi vesicle transport;GO:0048854//brain morphogenesis"	--
ENSG00000149922	0.376	0.375	0.558	0.53	0.648	0.374	14	16	16	16	22	11	TBX6	T-box transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:11605]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001707//mesoderm formation;GO:0001708//cell fate specification;GO:0001947//heart looping;GO:0003205//cardiac chamber development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007498//mesoderm development;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0010977//negative regulation of neuron projection development;GO:0014043//negative regulation of neuron maturation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0032525//somite rostral/caudal axis specification;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045944//positive regulation of transcription by RNA polymerase II"	T-box
ENSG00000149923	44.265	46.736	43.445	46.76	41.246	38.901	1194	1244	834	904	905	749	PPP4C	protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319]	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K15423	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030289//protein phosphatase 4 complex	GO:0004704//NF-kappaB-inducing kinase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0016576//histone dephosphorylation;GO:0033128//negative regulation of histone phosphorylation;GO:0038061//NIK/NF-kappaB signaling;GO:2000779//regulation of double-strand break repair	--
ENSG00000149925	973.169	1047.126	1009.026	1230.857	1159.553	930.353	30152.64	32504.61	23044.9	28209.26	30200.73	20936.84	ALDOA	"aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]"	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K01623;K01623;K01623;K01623;K01623;K01623;K01623	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0031430//M band;GO:0031674//I band;GO:0034774//secretory granule lumen;GO:0061827//sperm head;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0003824//catalytic activity;GO:0004332//fructose-bisphosphate aldolase activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0015631//tubulin binding;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0070061//fructose binding	"GO:0006000//fructose metabolic process;GO:0006096//glycolytic process;GO:0006754//ATP biosynthetic process;GO:0006941//striated muscle contraction;GO:0007015//actin filament organization;GO:0007339//binding of sperm to zona pellucida;GO:0008360//regulation of cell shape;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0046716//muscle cell cellular homeostasis;GO:0051289//protein homotetramerization"	--
ENSG00000149926	0.033	0	0.088	0	0.082	0	1	0	2	0	3	0	TLCD3B	TLC domain containing 3B [Source:HGNC Symbol;Acc:HGNC:25295]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0046513//ceramide biosynthetic process;GO:0055088//lipid homeostasis	--
ENSG00000149927	0.145	0.096	0.156	0.263	0.367	0.285	6.05	3	2	6.01	9.02	7	DOC2A	double C2 domain alpha [Source:HGNC Symbol;Acc:HGNC:2985]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005764//lysosome;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098850//extrinsic component of synaptic vesicle membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0016079//synaptic vesicle exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0061669//spontaneous neurotransmitter secretion	--
ENSG00000149929	4.436	5.87	5.695	4.383	4.216	4.732	204	241	174	134	142	131	HIRIP3	HIRA interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:4917]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0006333//chromatin assembly or disassembly	--
ENSG00000149930	15.214	14.156	17.412	17.726	16.835	18.031	1501	1416	1284	1312	1412	1299	TAOK2	TAO kinase 2 [Source:HGNC Symbol;Acc:HGNC:16835]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04429	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0038191//neuropilin binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0006612//protein targeting to membrane;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007409//axonogenesis;GO:0008360//regulation of cell shape;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0031954//positive regulation of protein autophosphorylation;GO:0032147//activation of protein kinase activity;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0032956//regulation of actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048041//focal adhesion assembly;GO:0048812//neuron projection morphogenesis;GO:0051403//stress-activated MAPK cascade;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0150019//basal dendrite morphogenesis;GO:0150020//basal dendrite arborization	--
ENSG00000149932	52.504	52.278	59.723	66.23	57.764	54.844	952	974	801	899	888	723	TMEM219	transmembrane protein 219 [Source:HGNC Symbol;Acc:HGNC:25201]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process	--
ENSG00000149948	1.538	1.754	0.999	1.296	1.178	1.046	112	119	56	82	85	65	HMGA2	high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:HGNC:5009]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05202//Transcriptional misregulation in cancer;ko05206//MicroRNAs in cancer	K09283;K09283	GO:0000228//nuclear chromosome;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032993//protein-DNA complex;GO:0035985//senescence-associated heterochromatin focus;GO:0071141//SMAD protein complex	"GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0031492//nucleosomal DNA binding;GO:0035497//cAMP response element binding;GO:0035500//MH2 domain binding;GO:0035501//MH1 domain binding;GO:0046332//SMAD binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070742//C2H2 zinc finger domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001837//epithelial to mesenchymal transition;GO:0002062//chondrocyte differentiation;GO:0003131//mesodermal-endodermal cell signaling;GO:0006284//base-excision repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0009615//response to virus;GO:0010564//regulation of cell cycle process;GO:0010628//positive regulation of gene expression;GO:0030261//chromosome condensation;GO:0031052//chromosome breakage;GO:0031507//heterochromatin assembly;GO:0035978//histone H2A-S139 phosphorylation;GO:0035987//endodermal cell differentiation;GO:0035988//chondrocyte proliferation;GO:0040008//regulation of growth;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043922//negative regulation by host of viral transcription;GO:0045444//fat cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048333//mesodermal cell differentiation;GO:0048762//mesenchymal cell differentiation;GO:0048863//stem cell differentiation;GO:0051301//cell division;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090402//oncogene-induced cell senescence;GO:2000036//regulation of stem cell population maintenance;GO:2000648//positive regulation of stem cell proliferation;GO:2000685//positive regulation of cellular response to X-ray;GO:2000773//negative regulation of cellular senescence;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining"	HMGA
ENSG00000149968	0.106	0.303	0.179	0.036	0.063	0	4	2	5	1	2	0	MMP3	matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: viral;Cancer: overview;Cardiovascular disease;Immune disease;Signal transduction;Cancer: specific types;Immune system	ko05171//Coronavirus disease - COVID-19;ko05202//Transcriptional misregulation in cancer;ko05417//Lipid and atherosclerosis;ko05323//Rheumatoid arthritis;ko04668//TNF signaling pathway;ko05215//Prostate cancer;ko04657//IL-17 signaling pathway	K01394;K01394;K01394;K01394;K01394;K01394;K01394	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0031334//positive regulation of protein-containing complex assembly;GO:0071492//cellular response to UV-A;GO:0071732//cellular response to nitric oxide;GO:0150077//regulation of neuroinflammatory response;GO:1903209//positive regulation of oxidative stress-induced cell death;GO:1904645//response to amyloid-beta	--
ENSG00000149970	2.583	2.129	1.876	1.418	1.474	2.027	254	203	154	117	133	146	CNKSR2	connector enhancer of kinase suppressor of Ras 2 [Source:HGNC Symbol;Acc:HGNC:19701]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K17536	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0099147//extrinsic component of postsynaptic density membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding	GO:0009966//regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0099173//postsynapse organization	--
ENSG00000149972	0.298	0.185	0.123	0.18	0.111	0.071	35	25	10	13	9	7	CNTN5	contactin 5 [Source:HGNC Symbol;Acc:HGNC:2175]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0098982//GABA-ergic synapse;GO:0099026//anchored component of presynaptic membrane	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007605//sensory perception of sound;GO:0098609//cell-cell adhesion;GO:0099054//presynapse assembly	--
ENSG00000150045	0	0	0	0	0	0	0	0	0	0	0	0	KLRF1	killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0032393//MHC class I receptor activity	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000150048	0	0	0.232	0.024	0	0.025	0	0	2	1	0	1	CLEC1A	C-type lectin domain family 1 member A [Source:HGNC Symbol;Acc:HGNC:24355]	-	-	-	-	GO:0005622//intracellular anatomical structure;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000150051	0.631	0.298	0	0.198	0.19	0.367	18	13	0	11	12	20	MKX	mohawk homeobox [Source:HGNC Symbol;Acc:HGNC:23729]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0048468//cell development"	Homeobox
ENSG00000150054	3.246	2.933	2.581	2.091	2.971	2.566	323	277	180	161	216	197	MPP7	membrane palmitoylated protein 7 [Source:HGNC Symbol;Acc:HGNC:26542]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0097025//MPP7-DLG1-LIN7 complex	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0035591//signaling adaptor activity;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity	GO:0030010//establishment of cell polarity;GO:0031334//positive regulation of protein-containing complex assembly;GO:0070830//bicellular tight junction assembly;GO:0071896//protein localization to adherens junction	--
ENSG00000150093	139.68	131.387	103.418	80.428	92.517	92.082	10884	10275	5947	4630	6084	5215	ITGB1	integrin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6153]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Signal transduction;Transport and catabolism;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Development and regeneration;Cellular community - eukaryotes;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04360//Axon guidance;ko04530//Tight junction;ko05414//Dilated cardiomyopathy;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko04611//Platelet activation;ko04670//Leukocyte transendothelial migration;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05100//Bacterial invasion of epithelial cells;ko05133//Pertussis;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719;K05719	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0034665//integrin alpha1-beta1 complex;GO:0034666//integrin alpha2-beta1 complex;GO:0034667//integrin alpha3-beta1 complex;GO:0034668//integrin alpha4-beta1 complex;GO:0034674//integrin alpha5-beta1 complex;GO:0034677//integrin alpha7-beta1 complex;GO:0034678//integrin alpha8-beta1 complex;GO:0034680//integrin alpha10-beta1 complex;GO:0034681//integrin alpha11-beta1 complex;GO:0035748//myelin sheath abaxonal region;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0097060//synaptic membrane;GO:0097386//glial cell projection;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099699//integral component of synaptic membrane	GO:0001618//virus receptor activity;GO:0001968//fibronectin binding;GO:0002020//protease binding;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0019960//C-X3-C chemokine binding;GO:0038023//signaling receptor activity;GO:0043236//laminin binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0050839//cell adhesion molecule binding;GO:0098639//collagen binding involved in cell-matrix adhesion;GO:1990782//protein tyrosine kinase binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000132//establishment of mitotic spindle orientation;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006909//phagocytosis;GO:0006968//cellular defense response;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007161//calcium-independent cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007520//myoblast fusion;GO:0008284//positive regulation of cell population proliferation;GO:0008354//germ cell migration;GO:0008542//visual learning;GO:0010710//regulation of collagen catabolic process;GO:0010763//positive regulation of fibroblast migration;GO:0016477//cell migration;GO:0021943//formation of radial glial scaffolds;GO:0023035//CD40 signaling pathway;GO:0030030//cell projection organization;GO:0030032//lamellipodium assembly;GO:0030183//B cell differentiation;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0031175//neuron projection development;GO:0031589//cell-substrate adhesion;GO:0031623//receptor internalization;GO:0033627//cell adhesion mediated by integrin;GO:0033631//cell-cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035313//wound healing, spreading of epidermal cells;GO:0035633//maintenance of blood-brain barrier;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045214//sarcomere organization;GO:0045445//myoblast differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0046718//viral entry into host cell;GO:0048333//mesodermal cell differentiation;GO:0048675//axon extension;GO:0048813//dendrite morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050901//leukocyte tethering or rolling;GO:0051726//regulation of cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0051951//positive regulation of glutamate uptake involved in transmission of nerve impulse;GO:0055007//cardiac muscle cell differentiation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071711//basement membrane organization;GO:0090303//positive regulation of wound healing;GO:0150003//regulation of spontaneous synaptic transmission;GO:0150103//reactive gliosis;GO:1901979//regulation of inward rectifier potassium channel activity;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000273//positive regulation of signaling receptor activity;GO:2000811//negative regulation of anoikis"	--
ENSG00000150201	0	0	0	0	0	0	0	0	0	0	0	0	FXYD4	FXYD domain containing ion transport regulator 4 [Source:HGNC Symbol;Acc:HGNC:4028]	Organismal Systems	Excretory system	ko04960//Aldosterone-regulated sodium reabsorption	K13359	GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005267//potassium channel activity;GO:0017080//sodium channel regulator activity;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0043269//regulation of ion transport;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000150244	0	0	0	0	0	0	0	0	0	0	0	0	TRIM48	tripartite motif containing 48 [Source:HGNC Symbol;Acc:HGNC:19021]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000150261	0	0	0	0	0	0	0	0	0	0	0	0	OR8K1	olfactory receptor family 8 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:14831]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000150269	0	0	0	0	0	0	0	0	0	0	0	0	OR5M9	olfactory receptor family 5 subfamily M member 9 [Source:HGNC Symbol;Acc:HGNC:15294]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000150275	0.118	0.227	0.111	0.637	0.24	0.125	10	14	9	20	9	8	PCDH15	protocadherin related 15 [Source:HGNC Symbol;Acc:HGNC:14674]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032420//stereocilium;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0001964//startle response;GO:0002009//morphogenesis of an epithelium;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0007628//adult walking behavior;GO:0035264//multicellular organism growth;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045494//photoreceptor cell maintenance;GO:0048839//inner ear development;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0050973//detection of mechanical stimulus involved in equilibrioception;GO:0060013//righting reflex;GO:0060088//auditory receptor cell stereocilium organization;GO:0060122//inner ear receptor cell stereocilium organization;GO:1905515//non-motile cilium assembly	--
ENSG00000150281	3.783	3.618	3.494	5.236	3.263	3.729	129	124	88	132	94	91	CTF1	cardiotrophin 1 [Source:HGNC Symbol;Acc:HGNC:2499]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05422;K05422	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005146//leukemia inhibitory factor receptor binding;GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0008284//positive regulation of cell population proliferation;GO:0030182//neuron differentiation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0048666//neuron development;GO:0048861//leukemia inhibitory factor signaling pathway	--
ENSG00000150316	13.684	15.442	15.612	11.076	12.41	11.363	432	490	364	259	331	261	CWC15	CWC15 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:26939]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12863	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005739//mitochondrion;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000150337	0	0	0	0	0.086	0	0	0	0	0	2	0	FCGR1A	Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Transport and catabolism;Immune disease;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: parasitic;Development and regeneration;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko05221//Acute myeloid leukemia	K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019771//high-affinity IgG receptor activity;GO:0019864//IgG binding	"GO:0001788//antibody-dependent cellular cytotoxicity;GO:0002376//immune system process;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0038094//Fc-gamma receptor signaling pathway;GO:0045087//innate immune response;GO:0050776//regulation of immune response;GO:0061098//positive regulation of protein tyrosine kinase activity"	--
ENSG00000150347	11.003	10.918	8.677	6.77	8.1	9.809	1520	1483	917	700	974	980	ARID5B	AT-rich interaction domain 5B [Source:HGNC Symbol;Acc:HGNC:17362]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0001889//liver development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006807//nitrogen compound metabolic process;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009791//post-embryonic development;GO:0010761//fibroblast migration;GO:0030325//adrenal gland development;GO:0035264//multicellular organism growth;GO:0045444//fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048468//cell development;GO:0048644//muscle organ morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0060612//adipose tissue development;GO:0060613//fat pad development;GO:1990830//cellular response to leukemia inhibitory factor"	ARID
ENSG00000150361	0	0	0	0	0	0.017	0	0	0	0	0	1	KLHL1	kelch like family member 1 [Source:HGNC Symbol;Acc:HGNC:6352]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007626//locomotory behavior;GO:0007628//adult walking behavior;GO:0016358//dendrite development;GO:0021680//cerebellar Purkinje cell layer development;GO:0030036//actin cytoskeleton organization	--
ENSG00000150394	0.131	0.113	0.187	0.049	0.1	0.118	12	10	8	3	7	7	CDH8	cadherin 8 [Source:HGNC Symbol;Acc:HGNC:1767]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0043083//synaptic cleft;GO:0043679//axon terminus;GO:0097060//synaptic membrane;GO:0098978//glutamatergic synapse	GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	"GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0009409//response to cold;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0035249//synaptic transmission, glutamatergic;GO:0050807//regulation of synapse organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules"	--
ENSG00000150401	5.058	4.769	3.242	5.131	3.704	5.106	224	177	137	124	148	149	DCUN1D2	defective in cullin neddylation 1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20328]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding	GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:2000434//regulation of protein neddylation;GO:2000436//positive regulation of protein neddylation	--
ENSG00000150403	26.109	28.166	24.686	26.582	30.638	28.016	1653	1782	1150	1234	1455	1270	TMCO3	transmembrane and coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:20329]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0051179//localization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000150433	8.042	7.931	8.923	9.472	6.364	6.426	215	228	163	164	179	142	TMEM218	transmembrane protein 218 [Source:HGNC Symbol;Acc:HGNC:27344]	-	-	-	-	GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000150455	2.856	3.316	4.71	2.956	3.513	3.319	122	132	133	91	122	105	TIRAP	TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Immune system;Cancer: overview;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko05161//Hepatitis B;ko04936//Alcoholic liver disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis	K05403;K05403;K05403;K05403;K05403;K05403;K05403;K05403;K05403;K05403	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0032587//ruffle membrane	"GO:0003953//NAD+ nucleosidase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0030674//protein-macromolecule adaptor activity;GO:0035662//Toll-like receptor 4 binding;GO:0035663//Toll-like receptor 2 binding;GO:0042802//identical protein binding"	GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0030099//myeloid cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032496//response to lipopolysaccharide;GO:0032648//regulation of interferon-beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032738//positive regulation of interleukin-15 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032872//regulation of stress-activated MAPK cascade;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0035665//TIRAP-dependent toll-like receptor 4 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0045089//positive regulation of innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0071221//cellular response to bacterial lipopeptide;GO:0071223//cellular response to lipoteichoic acid;GO:0090023//positive regulation of neutrophil chemotaxis;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000150456	3.441	5.468	5.123	4.116	3.946	3.821	69	106	71	60	63	55	EEF1AKMT1	EEF1A lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27351]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0032259//methylation	--
ENSG00000150457	7.05	6.91	6.297	5.997	6.163	6.499	811	799	535	511	599	544	LATS2	large tumor suppressor kinase 2 [Source:HGNC Symbol;Acc:HGNC:6515]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K08791;K08791	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0009755//hormone-mediated signaling pathway;GO:0016310//phosphorylation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0046620//regulation of organ growth;GO:0051301//cell division;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000150459	40.32	43.725	42.609	35.782	36.032	35.783	1909	2010	1500	1236	1451	1241	SAP18	Sin3A associated protein 18 [Source:HGNC Symbol;Acc:HGNC:10530]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14324;K14324	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0061574//ASAP complex	GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000150471	5.142	3.761	2.846	2.251	2.203	2.028	645	466	262	180	225	187	ADGRL3	adhesion G protein-coupled receptor L3 [Source:HGNC Symbol;Acc:HGNC:20974]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0098978//glutamatergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007416//synapse assembly;GO:0007420//brain development;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000150477	3.543	3.64	3.09	3.157	3.594	3.673	250.35	242	148.02	122.64	163.19	153.72	KIAA1328	KIAA1328 [Source:HGNC Symbol;Acc:HGNC:29248]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000150510	35.382	32.53	36.549	27.804	29.047	35.547	2888	2725	2194	1696	2046	2059	FAM124A	family with sequence similarity 124 member A [Source:HGNC Symbol;Acc:HGNC:26413]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000150527	18.182	16.201	15.091	11.147	16.172	17.721	1068	962	600	511	720	752	MIA2	MIA SH3 domain ER export factor 2 [Source:HGNC Symbol;Acc:HGNC:18432]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0038024//cargo receptor activity	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0009306//protein secretion;GO:0032527//protein exit from endoplasmic reticulum;GO:0035459//vesicle cargo loading;GO:0042953//lipoprotein transport;GO:0050790//regulation of catalytic activity;GO:0070973//protein localization to endoplasmic reticulum exit site	--
ENSG00000150540	13.785	13.631	12.049	9.509	8.653	11.285	430	412	288	253	220	233	HNMT	histamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:5028]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K00546;K00546	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0016740//transferase activity;GO:0046539//histamine N-methyltransferase activity	GO:0001692//histamine metabolic process;GO:0001695//histamine catabolic process;GO:0006548//histidine catabolic process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0032259//methylation	--
ENSG00000150551	1.542	1.276	0.656	0.618	0.694	0.334	57.51	74	34.74	28.33	37.55	15.11	LYPD1	LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0045202//synapse	GO:0030550//acetylcholine receptor inhibitor activity;GO:0033130//acetylcholine receptor binding	"GO:0001662//behavioral fear response;GO:0007271//synaptic transmission, cholinergic;GO:0035094//response to nicotine;GO:0095500//acetylcholine receptor signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000272//negative regulation of signaling receptor activity"	--
ENSG00000150556	0.417	0.491	0.178	0.769	0.67	0.301	11	12	3	13	15	5	LYPD6B	LY6/PLAUR domain containing 6B [Source:HGNC Symbol;Acc:HGNC:27018]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25368	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0030548//acetylcholine receptor regulator activity	-	--
ENSG00000150593	49.48	46.22	46.884	28.399	34.022	32.79	2564.24	2541.37	1848.65	1225.49	1550.88	1378.2	PDCD4	programmed cell death 4 [Source:HGNC Symbol;Acc:HGNC:8763]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer	K16865;K16865	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006915//apoptotic process;GO:0007569//cell aging;GO:0030509//BMP signaling pathway;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043508//negative regulation of JUN kinase activity;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050729//positive regulation of inflammatory response;GO:0051246//regulation of protein metabolic process;GO:0060940//epithelial to mesenchymal transition involved in cardiac fibroblast development;GO:0071222//cellular response to lipopolysaccharide;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904761//negative regulation of myofibroblast differentiation;GO:1905064//negative regulation of vascular associated smooth muscle cell differentiation;GO:1905461//positive regulation of vascular associated smooth muscle cell apoptotic process;GO:2000353//positive regulation of endothelial cell apoptotic process"	--
ENSG00000150594	0.646	0.655	1.144	0.487	0.765	1.384	52	53	68	29	52	81	ADRA2A	adrenoceptor alpha 2A [Source:HGNC Symbol;Acc:HGNC:281]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04022//cGMP-PKG signaling pathway	K04138;K04138	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0043679//axon terminus;GO:0045202//synapse;GO:0098691//dopaminergic synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004938//alpha2-adrenergic receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031692//alpha-1B adrenergic receptor binding;GO:0031696//alpha-2C adrenergic receptor binding;GO:0031996//thioesterase binding;GO:0032795//heterotrimeric G-protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding	GO:0001819//positive regulation of cytokine production;GO:0002526//acute inflammatory response;GO:0006260//DNA replication;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell population proliferation;GO:0010700//negative regulation of norepinephrine secretion;GO:0019229//regulation of vasoconstriction;GO:0030036//actin cytoskeleton organization;GO:0030168//platelet activation;GO:0030335//positive regulation of cell migration;GO:0032147//activation of protein kinase activity;GO:0032148//activation of protein kinase B activity;GO:0032811//negative regulation of epinephrine secretion;GO:0032870//cellular response to hormone stimulus;GO:0035624//receptor transactivation;GO:0042311//vasodilation;GO:0042593//glucose homeostasis;GO:0042596//fear response;GO:0043268//positive regulation of potassium ion transport;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0046676//negative regulation of insulin secretion;GO:0050892//intestinal absorption;GO:0050955//thermoception;GO:0050995//negative regulation of lipid catabolic process;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051926//negative regulation of calcium ion transport;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070473//negative regulation of uterine smooth muscle contraction;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0071881//adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0071882//phospholipase C-activating adrenergic receptor signaling pathway;GO:0090303//positive regulation of wound healing;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000150625	65.764	64.613	75.901	86.982	78.001	82.106	3726	3637	3162	3549	3687	3328	GPM6A	glycoprotein M6A [Source:HGNC Symbol;Acc:HGNC:4460]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044295//axonal growth cone;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane;GO:1903561//extracellular vesicle	GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0003407//neural retina development;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0009617//response to bacterium;GO:0031175//neuron projection development;GO:0048812//neuron projection morphogenesis;GO:0048863//stem cell differentiation;GO:0050807//regulation of synapse organization;GO:0051491//positive regulation of filopodium assembly;GO:0070588//calcium ion transmembrane transport	--
ENSG00000150627	1.118	0.821	0.996	0.937	0.855	1.002	170	117	100	79	104	99	WDR17	WD repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:16661]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000150628	0.138	0.378	0.286	0.684	0.5	0.174	4	9	5	12	10	3	SPATA4	spermatogenesis associated 4 [Source:HGNC Symbol;Acc:HGNC:17333]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005930//axoneme	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0051493//regulation of cytoskeleton organization	--
ENSG00000150630	1.238	1.677	1.618	3.832	4.623	3.93	58	79	56	133	183	134	VEGFC	vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes;Endocrine system;Signal transduction;Endocrine and metabolic disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04926//Relaxin signaling pathway;ko04668//TNF signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications	K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen	GO:0005172//vascular endothelial growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity;GO:0043185//vascular endothelial growth factor receptor 3 binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0002052//positive regulation of neuroblast proliferation;GO:0006929//substrate-dependent cell migration;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009887//animal organ morphogenesis;GO:0016331//morphogenesis of embryonic epithelium;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031954//positive regulation of protein autophosphorylation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045668//negative regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045776//negative regulation of blood pressure;GO:0045860//positive regulation of protein kinase activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051781//positive regulation of cell division;GO:0060754//positive regulation of mast cell chemotaxis;GO:1901492//positive regulation of lymphangiogenesis;GO:1902462//positive regulation of mesenchymal stem cell proliferation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000150636	0.253	0.203	0.21	0.11	0.057	0.539	5	5	5	2	2	10	CCDC102B	coiled-coil domain containing 102B [Source:HGNC Symbol;Acc:HGNC:26295]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000150637	0.025	0.064	0.03	0	0.077	0.005	4	4	1	0	2	1	CD226	CD226 molecule [Source:HGNC Symbol;Acc:HGNC:16961]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06567	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0050839//cell adhesion molecule binding	GO:0002729//positive regulation of natural killer cell cytokine production;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0008037//cell recognition;GO:0032729//positive regulation of interferon-gamma production;GO:0033005//positive regulation of mast cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0060369//positive regulation of Fc receptor mediated stimulatory signaling pathway	--
ENSG00000150656	0.412	0.297	0.316	1.398	0.461	0.244	37	25	21	32	26	16	CNDP1	carnosine dipeptidase 1 [Source:HGNC Symbol;Acc:HGNC:20675]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism	K05604;K05604;K05604;K05604	GO:0005576//extracellular region;GO:0005829//cytosol	GO:0004180//carboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity	GO:0006508//proteolysis;GO:0032268//regulation of cellular protein metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000150667	0.77	0.613	0.881	0.406	0.426	0.424	45	36	38	17	21	18	FSIP1	fibrous sheath interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21674]	-	-	-	-	-	-	-	--
ENSG00000150672	2.567	1.764	1.061	1.634	1.348	0.752	128	95	50	58	43	56	DLG2	discs large MAGUK scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:2901]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko04530//Tight junction;ko04390//Hippo signaling pathway	K12075;K12075;K12075	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0008076//voltage-gated potassium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0044224//juxtaparanode region of axon;GO:0045202//synapse;GO:0098839//postsynaptic density membrane;GO:0110165//cellular anatomical entity;GO:1904115//axon cytoplasm	GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0019900//kinase binding	GO:0007268//chemical synaptic transmission;GO:0035865//cellular response to potassium ion;GO:0043113//receptor clustering;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:0099641//anterograde axonal protein transport;GO:0099642//retrograde axonal protein transport	--
ENSG00000150676	0	0	0	0	0	0	0	0	0	0	0	0	CCDC83	coiled-coil domain containing 83 [Source:HGNC Symbol;Acc:HGNC:28535]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000150681	0	0	0	0	0	0	0	0	0	0	0	0	RGS18	regulator of G protein signaling 18 [Source:HGNC Symbol;Acc:HGNC:14261]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000150687	36.73	37.943	20.663	23.215	27.716	21.892	2786.55	2899.07	1154	1281.22	1760.65	1207.05	PRSS23	serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000150712	16.536	15.365	15.577	14.531	15.263	15.184	1571	1467	1067	941	1180	1048	MTMR12	myotubularin related protein 12 [Source:HGNC Symbol;Acc:HGNC:18191]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0030017//sarcomere	GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity	GO:0046856//phosphatidylinositol dephosphorylation;GO:0050790//regulation of catalytic activity;GO:1901998//toxin transport	--
ENSG00000150722	0.617	0.212	0.062	0.248	0.264	0.184	15	6	1	4	5	3	PPP1R1C	protein phosphatase 1 regulatory inhibitor subunit 1C [Source:HGNC Symbol;Acc:HGNC:14940]	-	-	-	-	GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0051301//cell division	--
ENSG00000150750	0.046	0	0	0	0	0.189	1	0	0	0	0	3	C11orf53	chromosome 11 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:30527]	-	-	-	-	-	-	-	--
ENSG00000150753	64.257	60.565	64.922	60.136	57.115	57.331	2804	2755	2146	2008	2167	1904	CCT5	chaperonin containing TCP1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:1618]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031681//G-protein beta-subunit binding;GO:0044183//protein folding chaperone;GO:0048027//mRNA 5'-UTR binding;GO:0048487//beta-tubulin binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0009615//response to virus;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000150756	4.801	5.569	5.591	4.425	4.901	5.672	208	235	183	142	189	185	ATPSCKMT	ATP synthase c subunit lysine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:27029]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030061//mitochondrial crista;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	"GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation;GO:1904058//positive regulation of sensory perception of pain;GO:1905273//positive regulation of proton-transporting ATP synthase activity, rotational mechanism;GO:1905706//regulation of mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000150760	12.254	12.756	10.351	7.91	9.143	8.812	1732	1813	1081	828	1091	906	DOCK1	dedicator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:2987]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K13708;K13708;K13708;K13708;K13708;K13708	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0032045//guanyl-nucleotide exchange factor complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	"GO:0002244//hematopoietic progenitor cell differentiation;GO:0006909//phagocytosis;GO:0006911//phagocytosis, engulfment;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0010634//positive regulation of epithelial cell migration;GO:0016477//cell migration;GO:0050790//regulation of catalytic activity;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading"	--
ENSG00000150764	20.644	19.626	17.885	19.126	19.391	19.123	2179	2114	1433	1539	1754	1514	DIXDC1	DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0043679//axon terminus	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0043015//gamma-tubulin binding	GO:0016055//Wnt signaling pathway;GO:0021695//cerebellar cortex development;GO:0021795//cerebral cortex cell migration;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021846//cell proliferation in forebrain;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0030177//positive regulation of Wnt signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0045665//negative regulation of neuron differentiation;GO:0046330//positive regulation of JNK cascade;GO:0050772//positive regulation of axonogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000150768	13.198	12.209	13.994	12.837	12.062	13.877	916.44	849	703.2	673	704	688	DLAT	dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K00627;K00627;K00627;K00627;K00627	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045254//pyruvate dehydrogenase complex;GO:1990204//oxidoreductase complex	GO:0004742//dihydrolipoyllysine-residue acetyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030523//dihydrolipoamide S-acyltransferase activity;GO:0034604//pyruvate dehydrogenase (NAD+) activity;GO:0042802//identical protein binding	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006082//organic acid metabolic process;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0006090//pyruvate metabolic process;GO:0006099//tricarboxylic acid cycle	--
ENSG00000150773	1.745	1.884	1.061	1.201	1.087	2.131	52.56	48	23.8	15	25	42	PIH1D2	PIH1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25210]	-	-	-	-	GO:0005737//cytoplasm;GO:0097255//R2TP complex;GO:0101031//chaperone complex;GO:1990904//ribonucleoprotein complex	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000492//box C/D snoRNP assembly;GO:0006364//rRNA processing;GO:0050821//protein stabilization	--
ENSG00000150776	11.606	12.026	10.017	7.736	7.026	5.643	530.15	557.32	352.42	248.2	324.86	301.16	NKAPD1	NKAP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25569]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000150779	19.145	22.651	22	27.85	20.709	23.324	329.85	401.68	290.58	355.8	304.14	294.84	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B [Source:HGNC Symbol;Acc:HGNC:11818]	-	-	-	-	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0140318//protein transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000150782	8.903	5.988	6.513	17.507	15.561	16.512	197	139	111	288	293	261	IL18	interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: bacterial;Immune system;Infectious disease: viral;Immune disease;Infectious disease: parasitic;Signaling molecules and interaction;Immune disease;Immune system;Infectious disease: bacterial;Infectious disease: parasitic	ko04060//Cytokine-cytokine receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05323//Rheumatoid arthritis;ko05143//African trypanosomiasis;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05321//Inflammatory bowel disease;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis;ko05144//Malaria	K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482;K05482	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0045515//interleukin-18 receptor binding	GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008283//cell population proliferation;GO:0010468//regulation of gene expression;GO:0010604//positive regulation of macromolecule metabolic process;GO:0010628//positive regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030101//natural killer cell activation;GO:0030155//regulation of cell adhesion;GO:0030431//sleep;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0032722//positive regulation of chemokine production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032736//positive regulation of interleukin-13 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0034105//positive regulation of tissue remodeling;GO:0035655//interleukin-18-mediated signaling pathway;GO:0042088//T-helper 1 type immune response;GO:0042092//type 2 immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0042119//neutrophil activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042632//cholesterol homeostasis;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051142//positive regulation of NK T cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0061436//establishment of skin barrier;GO:0070328//triglyceride homeostasis;GO:0071407//cellular response to organic cyclic compound;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0150078//positive regulation of neuroinflammatory response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000556//positive regulation of T-helper 1 cell cytokine production	--
ENSG00000150783	0	0	0	0	0	0	0	0	0	0	0	0	TEX12	testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0000801//central element;GO:0005694//chromosome	GO:0005515//protein binding	GO:0000711//meiotic DNA repair synthesis;GO:0007130//synaptonemal complex assembly;GO:0051321//meiotic cell cycle	--
ENSG00000150787	9.434	10.759	9.437	10.219	8.305	8.649	160	180	124	129	125	113	PTS	6-pyruvoyltetrahydropterin synthase [Source:HGNC Symbol;Acc:HGNC:9689]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K01737;K01737	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003874//6-pyruvoyltetrahydropterin synthase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006520//cellular amino acid metabolic process;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0007417//central nervous system development	--
ENSG00000150867	10.519	11.564	14.289	15.346	11.707	9.036	588	661	466	470	505	439	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8997]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Cell motility;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04810//Regulation of actin cytoskeleton;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00920;K00920;K00920;K00920	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	"GO:0006629//lipid metabolic process;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0035855//megakaryocyte development;GO:0046488//phosphatidylinositol metabolic process;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0061909//autophagosome-lysosome fusion;GO:0090119//vesicle-mediated cholesterol transport;GO:0090217//negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:1902635//1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process;GO:2000786//positive regulation of autophagosome assembly"	--
ENSG00000150873	0.137	0.139	0.116	0.084	0.022	0.025	15	20	14	3	3	3	C2orf50	chromosome 2 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:26324]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000150893	1.184	0.857	1.142	0.787	0.857	1.106	396	288	282	195	242	269	FREM2	FRAS1 related extracellular matrix 2 [Source:HGNC Symbol;Acc:HGNC:25396]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K23380	GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001654//eye development;GO:0001822//kidney development;GO:0002009//morphogenesis of an epithelium;GO:0007154//cell communication;GO:0007155//cell adhesion;GO:0007507//heart development;GO:0042733//embryonic digit morphogenesis;GO:0048839//inner ear development	--
ENSG00000150907	5.431	5.802	4.846	5.631	6.132	6.134	651	699	429	500	621	535	FOXO1	forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Cancer: specific types;Aging;Aging	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko04211//Longevity regulating pathway;ko04213//Longevity regulating pathway - multiple species	K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201;K07201	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0043565//sequence-specific DNA binding;GO:0051721//protein phosphatase 2A binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001659//temperature homeostasis;GO:0001678//cellular glucose homeostasis;GO:0006111//regulation of gluconeogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006473//protein acetylation;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008286//insulin receptor signaling pathway;GO:0009267//cellular response to starvation;GO:0010508//positive regulation of autophagy;GO:0030154//cell differentiation;GO:0032869//cellular response to insulin stimulus;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0034599//cellular response to oxidative stress;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045444//fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045722//positive regulation of gluconeogenesis;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070417//cellular response to cold;GO:0070542//response to fatty acid;GO:0071455//cellular response to hyperoxia;GO:0071732//cellular response to nitric oxide;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097009//energy homeostasis;GO:0097150//neuronal stem cell population maintenance;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:2000177//regulation of neural precursor cell proliferation;GO:2000377//regulation of reactive oxygen species metabolic process"	Fork_head
ENSG00000150938	87.451	84.722	78.511	85.228	91.555	90.919	10498	10224	6910	7447	9106	7928	CRIM1	cysteine rich transmembrane BMP regulator 1 [Source:HGNC Symbol;Acc:HGNC:2359]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004857//enzyme inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005010//insulin-like growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0030165//PDZ domain binding	GO:0001558//regulation of cell growth;GO:0007399//nervous system development;GO:0010951//negative regulation of endopeptidase activity;GO:0030514//negative regulation of BMP signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0045668//negative regulation of osteoblast differentiation;GO:0048009//insulin-like growth factor receptor signaling pathway	--
ENSG00000150961	8.109	6.864	6.008	4.822	5.084	5.051	649	538	346	252	358	293	SEC24D	"SEC24 homolog D, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10706]"	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05130//Pathogenic Escherichia coli infection;ko04141//Protein processing in endoplasmic reticulum	K14007;K14007	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000150967	31.486	33.725	26.496	32.286	35.369	33.276	2086.52	2310.46	1334.92	1626.88	2055.59	1677.32	ABCB9	ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04142//Lysosome;ko02010//ABC transporters	K05656;K05656	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042824//MHC class I peptide loading complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015421//ABC-type oligopeptide transporter activity;GO:0015433//ABC-type peptide antigen transporter activity;GO:0015440//ABC-type peptide transporter activity;GO:0022857//transmembrane transporter activity;GO:0042288//MHC class I protein binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046978//TAP1 binding;GO:0140359//ABC-type transporter activity	GO:0006518//peptide metabolic process;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0035672//oligopeptide transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000150977	6.577	4.983	5.85	5.424	4.788	4.954	239	182	157	146	147	131	RILPL2	Rab interacting lysosomal protein like 2 [Source:HGNC Symbol;Acc:HGNC:28787]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity	GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0060271//cilium assembly;GO:1903445//protein transport from ciliary membrane to plasma membrane	--
ENSG00000150990	5.885	5.667	6.014	6.196	6.196	6.54	556	538	420	434	495	450	DHX37	DEAH-box helicase 37 [Source:HGNC Symbol;Acc:HGNC:17210]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0034511//U3 snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007420//brain development;GO:0042254//ribosome biogenesis;GO:0042255//ribosome assembly;GO:2000020//positive regulation of male gonad development"	--
ENSG00000150991	575.974	648.332	602.321	499.722	495.973	492.165	22980	25943	17556	14591	16700	14106	UBC	ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Organismal Systems;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Folding, sorting and degradation;Endocrine system;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04120//Ubiquitin mediated proteolysis;ko03320//PPAR signaling pathway;ko04137//Mitophagy - animal	K08770;K08770;K08770;K08770;K08770;K08770;K08770	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0030666//endocytic vesicle membrane;GO:0031315//extrinsic component of mitochondrial outer membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding	GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process	--
ENSG00000150995	6.004	5.865	6.452	4.938	5.355	6.453	1173	1106	900	694	872	887	ITPR1	"inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Nervous system;Neurodegenerative disease;Cell growth and death;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine system;Nervous system;Nervous system;Nervous system;Immune system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Digestive system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04114//Oocyte meiosis;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression"	K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958;K04958	GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005955//calcineurin complex;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030658//transport vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031088//platelet dense granule membrane;GO:0031094//platelet dense tubular network;GO:0031095//platelet dense tubular network membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098685//Schaffer collateral - CA1 synapse	"GO:0005216//ion channel activity;GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0015278//calcium-release channel activity;GO:0019855//calcium channel inhibitor activity;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0098695//inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels"	GO:0000902//cell morphogenesis;GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0009791//post-embryonic development;GO:0010506//regulation of autophagy;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032879//regulation of localization;GO:0034220//ion transmembrane transport;GO:0042045//epithelial fluid transport;GO:0048016//inositol phosphate-mediated signaling;GO:0050849//negative regulation of calcium-mediated signaling;GO:0050882//voluntary musculoskeletal movement;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051239//regulation of multicellular organismal process;GO:0055085//transmembrane transport;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070588//calcium ion transmembrane transport;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1903779//regulation of cardiac conduction	--
ENSG00000151005	0	0	0	0	0	0	0	0	0	0	0	0	TKTL2	transketolase like 2 [Source:HGNC Symbol;Acc:HGNC:25313]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00615;K00615;K00615;K00615	GO:0005737//cytoplasm	GO:0003824//catalytic activity;GO:0004802//transketolase activity;GO:0016740//transferase activity;GO:0030976//thiamine pyrophosphate binding;GO:0046872//metal ion binding	-	--
ENSG00000151006	0.287	0.199	0.06	0	0.314	0.334	13	9.06	2	0	12	11	PRSS53	serine protease 53 [Source:HGNC Symbol;Acc:HGNC:34407]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000151012	3.254	2.153	1.753	1.383	2	5.097	651	433	259	205	338	658	SLC7A11	solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059]	Cellular Processes	Cell growth and death	ko04216//Ferroptosis	K13869	GO:0005791//rough endoplasmic reticulum;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045177//apical part of cell;GO:0097449//astrocyte projection	GO:0005515//protein binding;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015327//cystine:glutamate antiporter activity;GO:0022857//transmembrane transporter activity	GO:0006749//glutathione metabolic process;GO:0006865//amino acid transport;GO:0006979//response to oxidative stress;GO:0007420//brain development;GO:0008542//visual learning;GO:0009636//response to toxic substance;GO:0014070//response to organic cyclic compound;GO:0021591//ventricular system development;GO:0021756//striatum development;GO:0030534//adult behavior;GO:0033029//regulation of neutrophil apoptotic process;GO:0034599//cellular response to oxidative stress;GO:0034775//glutathione transmembrane transport;GO:0035094//response to nicotine;GO:0042127//regulation of cell population proliferation;GO:0048021//regulation of melanin biosynthetic process;GO:0048286//lung alveolus development;GO:0050804//modulation of chemical synaptic transmission;GO:0050807//regulation of synapse organization;GO:0051223//regulation of protein transport;GO:0051775//response to redox state;GO:0055085//transmembrane transport;GO:0060173//limb development;GO:0070306//lens fiber cell differentiation;GO:0070527//platelet aggregation;GO:0071702//organic substance transport;GO:0090461//glutamate homeostasis;GO:0098712//L-glutamate import across plasma membrane;GO:0140206//dipeptide import across plasma membrane;GO:1900407//regulation of cellular response to oxidative stress;GO:1901494//regulation of cysteine metabolic process;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903786//regulation of glutathione biosynthetic process;GO:1904717//regulation of AMPA glutamate receptor clustering;GO:2000211//regulation of glutamate metabolic process	--
ENSG00000151014	1.892	1.785	1.464	1.128	1.396	1.722	77	73	44	34	48	51	NOCT	nocturnin [Source:HGNC Symbol;Acc:HGNC:14254]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003824//catalytic activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0016787//hydrolase activity;GO:0019178//NADP phosphatase activity;GO:0046872//metal ion binding;GO:0102757//NADPH phosphatase activity	"GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006366//transcription by RNA polymerase II;GO:0006739//NADP metabolic process;GO:0007623//circadian rhythm;GO:0009991//response to extracellular stimulus;GO:0010629//negative regulation of gene expression;GO:0016311//dephosphorylation;GO:0032496//response to lipopolysaccharide;GO:0032922//circadian regulation of gene expression;GO:0033962//P-body assembly;GO:0042752//regulation of circadian rhythm;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045995//regulation of embryonic development;GO:0048255//mRNA stabilization;GO:0048511//rhythmic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000151023	0.77	0.728	1.033	0.104	0.201	0.111	30	28	18	4	9	3	ENKUR	"enkurin, TRPC channel interacting protein [Source:HGNC Symbol;Acc:HGNC:28388]"	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097228//sperm principal piece;GO:0097728//9+0 motile cilium;GO:0097729//9+2 motile cilium	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0017124//SH3 domain binding	GO:0030317//flagellated sperm motility;GO:0061966//establishment of left/right asymmetry	--
ENSG00000151025	0.077	0.111	0.151	0.151	0.149	0.085	11	16	16	16	18	9	GPR158	G protein-coupled receptor 158 [Source:HGNC Symbol;Acc:HGNC:23689]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0072659//protein localization to plasma membrane	--
ENSG00000151033	0	0	0	0	0	0	0	0	0	0	0	0	LYZL2	lysozyme like 2 [Source:HGNC Symbol;Acc:HGNC:29613]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13915	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process	--
ENSG00000151062	2.519	3.421	3.603	3.442	4.006	3.7	217	304	234	241	299	241	CACNA2D4	calcium voltage-gated channel auxiliary subunit alpha2delta 4 [Source:HGNC Symbol;Acc:HGNC:20202]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04861;K04861;K04861;K04861;K04861;K04861;K04861	GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0050908//detection of light stimulus involved in visual perception;GO:0070588//calcium ion transmembrane transport	--
ENSG00000151065	6.107	6.811	5.858	6.087	6.04	6.25	258	290	183	191	216	192	DCP1B	decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12611	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle	GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016787//hydrolase activity	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0043085//positive regulation of catalytic activity"	--
ENSG00000151067	4.623	4.865	4.083	3.005	3.561	3.846	698	675	482	350	496	419	CACNA1C	calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Signal transduction;Cancer: overview;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Circulatory system;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Endocrine system;Endocrine system;Cardiovascular disease;Circulatory system;Nervous system;Endocrine system;Sensory system;Cardiovascular disease;Endocrine system;Substance dependence;Nervous system;Endocrine system;Endocrine system;Endocrine and metabolic disease	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04930//Type II diabetes mellitus"	K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850;K04850	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030315//T-tubule;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008331//high voltage-gated calcium channel activity;GO:0046872//metal ion binding;GO:0051393//alpha-actinin binding;GO:0086007//voltage-gated calcium channel activity involved in cardiac muscle cell action potential;GO:0086056//voltage-gated calcium channel activity involved in AV node cell action potential	GO:0002520//immune system development;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007507//heart development;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035115//embryonic forelimb morphogenesis;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0043010//camera-type eye development;GO:0045762//positive regulation of adenylate cyclase activity;GO:0055085//transmembrane transport;GO:0060402//calcium ion transport into cytosol;GO:0061337//cardiac conduction;GO:0061577//calcium ion transmembrane transport via high voltage-gated calcium channel;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086045//membrane depolarization during AV node cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:0098912//membrane depolarization during atrial cardiac muscle cell action potential	--
ENSG00000151079	0.085	0.132	0.066	0.033	0.043	0.067	7	11	4	2.03	3	4	KCNA6	potassium voltage-gated channel subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:6225]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0034705//potassium channel complex;GO:0043679//axon terminus	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000151090	0.991	1.023	1.772	0.945	1.506	1.358	129	101	112	75	86	100	THRB	thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04919//Thyroid hormone signaling pathway	K08362;K08362	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070324//thyroid hormone binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002154//thyroid hormone mediated signaling pathway;GO:0002157//positive regulation of thyroid hormone mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007605//sensory perception of sound;GO:0007621//negative regulation of female receptivity;GO:0008016//regulation of heart contraction;GO:0008050//female courtship behavior;GO:0009755//hormone-mediated signaling pathway;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046549//retinal cone cell development;GO:0060509//type I pneumocyte differentiation;GO:0097067//cellular response to thyroid hormone stimulus;GO:0097474//retinal cone cell apoptotic process"	THR-like
ENSG00000151092	12.39	13.477	11.102	8.269	10.454	12.199	604	619	393	281	379	393	NGLY1	N-glycanase 1 [Source:HGNC Symbol;Acc:HGNC:17646]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K01456	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000224//peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006457//protein folding;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006516//glycoprotein catabolic process;GO:0006517//protein deglycosylation;GO:0019538//protein metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0071712//ER-associated misfolded protein catabolic process	--
ENSG00000151093	6.361	13.797	5.345	5.542	7.305	5.942	164	206	114	114	166	111	OXSM	"3-oxoacyl-ACP synthase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26063]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis;ko00780//Biotin metabolism	K09458;K09458;K09458;K09458	GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0051790//short-chain fatty acid biosynthetic process;GO:0051792//medium-chain fatty acid biosynthetic process	--
ENSG00000151116	5.934	5.416	5.193	4.017	3.763	3.945	438	332	244	212	247	228	UEVLD	UEV and lactate/malate dehyrogenase domains [Source:HGNC Symbol;Acc:HGNC:30866]	-	-	-	-	GO:0000813//ESCRT I complex;GO:0070062//extracellular exosome	"GO:0003674//molecular_function;GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043130//ubiquitin binding"	GO:0006464//cellular protein modification process;GO:0008150//biological_process;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0019752//carboxylic acid metabolic process	--
ENSG00000151117	22.802	23.75	26.042	19.704	19.823	22.522	1705.99	1786	1439	1092	1253	1226	TMEM86A	transmembrane protein 86A [Source:HGNC Symbol;Acc:HGNC:26890]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0047408//alkenylglycerophosphocholine hydrolase activity;GO:0047409//alkenylglycerophosphoethanolamine hydrolase activity	-	--
ENSG00000151131	2.419	1.211	0.928	0.895	0.942	0.338	219	191	124	118	155	120	NOPCHAP1	NOP protein chaperone 1 [Source:HGNC Symbol;Acc:HGNC:28628]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0062064//box C/D snoRNP complex binding	GO:0000492//box C/D snoRNP assembly	--
ENSG00000151135	21.883	17.289	16.66	14.728	13.53	15.068	1283	1103	766	641	729	655	TMEM263	transmembrane protein 263 [Source:HGNC Symbol;Acc:HGNC:28281]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000151136	0.511	0.398	0.252	0.931	0.581	0.661	34	28	14	40	30	32	BTBD11	BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:23844]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0060395//SMAD protein signal transduction	--
ENSG00000151148	13.546	14.851	15.206	14.347	16.32	15.248	1460	1591	1233	1100	1493	1235	UBE3B	ubiquitin protein ligase E3B [Source:HGNC Symbol;Acc:HGNC:13478]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10588	-	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000151150	15.277	13.991	12.264	10.248	12.895	13.498	1212	1061	731	663	886	709	ANK3	ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K10380	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0014731//spectrin-associated cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030315//T-tubule;GO:0030424//axon;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043034//costamere;GO:0043194//axon initial segment;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008093//cytoskeletal anchor activity;GO:0030507//spectrin binding;GO:0030674//protein-macromolecule adaptor activity;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding	GO:0000281//mitotic cytokinesis;GO:0007009//plasma membrane organization;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0007528//neuromuscular junction development;GO:0010628//positive regulation of gene expression;GO:0010650//positive regulation of cell communication by electrical coupling;GO:0010765//positive regulation of sodium ion transport;GO:0010960//magnesium ion homeostasis;GO:0019228//neuronal action potential;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0043001//Golgi to plasma membrane protein transport;GO:0043266//regulation of potassium ion transport;GO:0045184//establishment of protein localization;GO:0045838//positive regulation of membrane potential;GO:0071286//cellular response to magnesium ion;GO:0071709//membrane assembly;GO:0072659//protein localization to plasma membrane;GO:0072660//maintenance of protein location in plasma membrane;GO:0090314//positive regulation of protein targeting to membrane;GO:0099612//protein localization to axon;GO:1900827//positive regulation of membrane depolarization during cardiac muscle cell action potential;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:2001259//positive regulation of cation channel activity	--
ENSG00000151151	2.01	1.551	1.382	1.26	1.358	1.479	254	197	129	118	145	136	IPMK	inositol polyphosphate multikinase [Source:HGNC Symbol;Acc:HGNC:20739]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00915;K00915;K00915	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000166//nucleotide binding;GO:0000823//inositol-1,4,5-trisphosphate 6-kinase activity;GO:0000824//inositol tetrakisphosphate 3-kinase activity;GO:0000825//inositol tetrakisphosphate 6-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0047326//inositol tetrakisphosphate 5-kinase activity;GO:0051765//inositol tetrakisphosphate kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0097243//flavonoid binding;GO:0102732//myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity"	GO:0006629//lipid metabolic process;GO:0016310//phosphorylation;GO:0032957//inositol trisphosphate metabolic process;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0070266//necroptotic process	--
ENSG00000151164	0.125	0.12	0.095	0.122	0.105	0.049	9.06	9	6.04	4	5	2	RAD9B	RAD9 checkpoint clamp component B [Source:HGNC Symbol;Acc:HGNC:21700]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K10995	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030896//checkpoint clamp complex	GO:0005515//protein binding	GO:0000076//DNA replication checkpoint signaling;GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0071479//cellular response to ionizing radiation	--
ENSG00000151176	19.557	20.825	19.788	19.956	20.528	18.084	1538	1645	1157	1191	1356	1056	PLBD2	phospholipase B domain containing 2 [Source:HGNC Symbol;Acc:HGNC:27283]	-	-	-	-	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0004620//phospholipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process	--
ENSG00000151208	8.56	8.68	8.366	6.854	8.96	8.157	1318	1298	922	805	1127	903	DLG5	discs large MAGUK scaffold protein 5 [Source:HGNC Symbol;Acc:HGNC:2904]	Environmental Information Processing	Signal transduction	ko04390//Hippo signaling pathway	K24050	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008092//cytoskeletal protein binding;GO:0030159//signaling receptor complex adaptor activity	GO:0001837//epithelial to mesenchymal transition;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0030011//maintenance of cell polarity;GO:0030336//negative regulation of cell migration;GO:0030859//polarized epithelial cell differentiation;GO:0030901//midbrain development;GO:0035331//negative regulation of hippo signaling;GO:0035332//positive regulation of hippo signaling;GO:0035556//intracellular signal transduction;GO:0042130//negative regulation of T cell proliferation;GO:0042981//regulation of apoptotic process;GO:0045176//apical protein localization;GO:0045186//zonula adherens assembly;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051965//positive regulation of synapse assembly;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060999//positive regulation of dendritic spine development;GO:0065003//protein-containing complex assembly;GO:0071896//protein localization to adherens junction;GO:0072205//metanephric collecting duct development;GO:0098609//cell-cell adhesion	--
ENSG00000151224	0	0	0	0.038	0	0.02	0	0	0	2	0	1	MAT1A	methionine adenosyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:6903]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism	K00789;K00789;K00789	GO:0005829//cytosol;GO:0048269//methionine adenosyltransferase complex	GO:0000166//nucleotide binding;GO:0004478//methionine adenosyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006556//S-adenosylmethionine biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0009087//methionine catabolic process;GO:0051289//protein homotetramerization	--
ENSG00000151229	3.28	2.501	2.389	1.768	2.015	2.435	480	363	257	194	253	254	SLC2A13	solute carrier family 2 member 13 [Source:HGNC Symbol;Acc:HGNC:15956]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0031090//organelle membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0071944//cell periphery;GO:0097450//astrocyte end-foot	GO:0002020//protease binding;GO:0005365//myo-inositol transmembrane transporter activity;GO:0005366//myo-inositol:proton symporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity;GO:0051117//ATPase binding	GO:0015798//myo-inositol transport;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000151233	6.155	4.597	4.848	3.901	5.065	4.359	799	535	419	330	500	376	GXYLT1	glucoside xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27482]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K13676	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035252//UDP-xylosyltransferase activity;GO:0140563//UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity"	GO:0016266//O-glycan processing	--
ENSG00000151239	43.799	33.479	33.908	27.514	30.875	34.119	2602	2059	1457	1263	1555	1447	TWF1	twinfilin actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9620]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0030175//filopodium;GO:0032587//ruffle membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding"	GO:0010591//regulation of lamellipodium assembly;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010976//positive regulation of neuron projection development;GO:0030042//actin filament depolymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0042989//sequestering of actin monomers;GO:0043538//regulation of actin phosphorylation;GO:0051016//barbed-end actin filament capping	--
ENSG00000151240	16.135	17.12	15.509	11.47	13.604	13.337	2561	2660	1754	1309	1754	1519	DIP2C	disco interacting protein 2 homolog C [Source:HGNC Symbol;Acc:HGNC:29150]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000151247	31.066	24.293	27.834	24.053	23.463	28.866	1055	899	708	575	701	715	EIF4E	eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Endocrine system;Signal transduction;Aging;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko04150//mTOR signaling pathway;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K03259;K03259;K03259;K03259;K03259;K03259	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0010494//cytoplasmic stress granule;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0016442//RISC complex;GO:0033391//chromatoid body;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031370//eukaryotic initiation factor 4G binding;GO:0045182//translation regulator activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0001662//behavioral fear response;GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0019827//stem cell population maintenance;GO:0045665//negative regulation of neuron differentiation;GO:0045931//positive regulation of mitotic cell cycle;GO:0071549//cellular response to dexamethasone stimulus;GO:0099578//regulation of translation at postsynapse, modulating synaptic transmission"	--
ENSG00000151276	6.441	5.607	4.408	3.932	4.555	4.641	795	698	413	386	533	489	MAGI1	"membrane associated guanylate kinase, WW and PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:946]"	Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes	Signal transduction;Infectious disease: viral;Signal transduction;Cellular community - eukaryotes	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04015//Rap1 signaling pathway;ko04530//Tight junction	K05631;K05631;K05631;K05631	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0051393//alpha-actinin binding;GO:0060090//molecular adaptor activity	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0022409//positive regulation of cell-cell adhesion;GO:0065003//protein-containing complex assembly	--
ENSG00000151287	4.663	4.533	5.077	4.425	3.614	5.018	113	107	93	75	72	92	TEX30	testis expressed 30 [Source:HGNC Symbol;Acc:HGNC:25188]	-	-	-	-	-	GO:0016787//hydrolase activity	-	--
ENSG00000151292	8.392	6.929	6.684	6.168	6.106	6.292	475	426	291	233	292	242	CSNK1G3	casein kinase 1 gamma 3 [Source:HGNC Symbol;Acc:HGNC:2456]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K08958	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000151304	2.567	2.201	1.692	1.231	1.679	1.555	152	131	74	54	84	67	SRFBP1	serum response factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26333]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030686//90S preribosome;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding	GO:0030490//maturation of SSU-rRNA	--
ENSG00000151320	2.473	1.996	1.364	1.186	0.954	0.885	369	313	150	102	154	125	AKAP6	A-kinase anchoring protein 6 [Source:HGNC Symbol;Acc:HGNC:376]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005901//caveola;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030315//T-tubule;GO:0031965//nuclear membrane;GO:0034704//calcium channel complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0043495//protein-membrane adaptor activity;GO:0044325//transmembrane transporter binding;GO:0051018//protein kinase A binding;GO:0060090//molecular adaptor activity	GO:0001508//action potential;GO:0006605//protein targeting;GO:0010738//regulation of protein kinase A signaling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0019933//cAMP-mediated signaling;GO:0030307//positive regulation of cell growth;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060306//regulation of membrane repolarization;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071320//cellular response to cAMP;GO:0071345//cellular response to cytokine stimulus;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1902261//positive regulation of delayed rectifier potassium channel activity	--
ENSG00000151322	0.189	0.706	0.371	0.497	0.591	0.583	17	32	23	22	44	35	NPAS3	neuronal PAS domain protein 3 [Source:HGNC Symbol;Acc:HGNC:19311]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	bHLH
ENSG00000151327	11.038	13.207	13.231	10.06	10.687	9.208	310	306	244	212	208	180	FAM177A1	family with sequence similarity 177 member A1 [Source:HGNC Symbol;Acc:HGNC:19829]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000151332	9.711	9.075	9.966	7.326	7.873	8.705	319	300	244	180	221	203	MBIP	MAP3K12 binding inhibitory protein 1 [Source:HGNC Symbol;Acc:HGNC:20427]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0031063//regulation of histone deacetylation;GO:0043086//negative regulation of catalytic activity;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045995//regulation of embryonic development;GO:0046330//positive regulation of JNK cascade;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000151338	1.858	0.775	0.762	1.388	0.57	1.829	111	50	48	31	34	53	MIPOL1	mirror-image polydactyly 1 [Source:HGNC Symbol;Acc:HGNC:21460]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000151348	29.812	35.539	32.557	31.795	33.248	31.585	2523	2888	2000	1898	2305	1911	EXT2	exostosin glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3513]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02367;K02367	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043541//UDP-N-acetylglucosamine transferase complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	"GO:0001503//ossification;GO:0001707//mesoderm formation;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0010467//gene expression;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030154//cell differentiation;GO:0030210//heparin biosynthetic process;GO:0033692//cellular polysaccharide biosynthetic process;GO:0042044//fluid transport;GO:0042311//vasodilation;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0050891//multicellular organismal water homeostasis;GO:0051923//sulfation;GO:0055078//sodium ion homeostasis;GO:0060047//heart contraction;GO:0060350//endochondral bone morphogenesis"	--
ENSG00000151353	12.409	14.076	14.625	12.466	12.174	16.836	478	466	394	379	383	407	TMEM18	transmembrane protein 18 [Source:HGNC Symbol;Acc:HGNC:25257]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0016477//cell migration	--
ENSG00000151360	0	0	0	0	0	0	0	0	0	0	0	0	ALLC	allantoicase [Source:HGNC Symbol;Acc:HGNC:17377]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01477;K01477	-	GO:0004037//allantoicase activity;GO:0016787//hydrolase activity	GO:0000256//allantoin catabolic process	--
ENSG00000151364	9.487	6.889	9.989	7.625	9.516	6.535	329.22	240.3	256	196	279	165	KCTD14	potassium channel tetramerization domain containing 14 [Source:HGNC Symbol;Acc:HGNC:23295]	-	-	-	-	-	GO:0005515//protein binding	GO:0051260//protein homooligomerization	--
ENSG00000151365	0	0	0	0	0.097	0	0	0	0	0	2	0	THRSP	thyroid hormone responsive [Source:HGNC Symbol;Acc:HGNC:11800]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006629//lipid metabolic process;GO:0009617//response to bacterium;GO:0010866//regulation of triglyceride biosynthetic process;GO:0046890//regulation of lipid biosynthetic process	--
ENSG00000151366	117.999	120.957	123.36	146.185	119.743	132.965	1616.25	1666.32	1290.97	1509.51	1403.93	1382.6	NDUFC2	NADH:ubiquinone oxidoreductase subunit C2 [Source:HGNC Symbol;Acc:HGNC:7706]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000151376	10.574	23.015	21.311	16.301	16.508	19.675	431	486	394	437	427	496	ME3	malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985]	Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Global and overview maps;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko03320//PPAR signaling pathway;ko00620//Pyruvate metabolism	K00029;K00029;K00029;K00029	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004470//malic enzyme activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0008948//oxaloacetate decarboxylase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051287//NAD binding;GO:0070401//NADP+ binding	GO:0006090//pyruvate metabolic process;GO:0006108//malate metabolic process;GO:0009060//aerobic respiration;GO:0072592//oxygen metabolic process	--
ENSG00000151379	0.396	0.143	0.195	0.049	0.043	0	11	4	4	1	1	0	MSGN1	mesogenin 1 [Source:HGNC Symbol;Acc:HGNC:14907]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001707//mesoderm formation;GO:0001756//somitogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007379//segment specification;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	bHLH
ENSG00000151388	5.034	5.638	5.216	5.718	4.327	3.859	895	899	526	557	586	432	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif 12 [Source:HGNC Symbol;Acc:HGNC:14605]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001503//ossification;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0006508//proteolysis;GO:0007160//cell-matrix adhesion;GO:0016477//cell migration;GO:0030167//proteoglycan catabolic process;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0032331//negative regulation of chondrocyte differentiation;GO:0043931//ossification involved in bone maturation;GO:0050727//regulation of inflammatory response;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071773//cellular response to BMP stimulus;GO:1901509//regulation of endothelial tube morphogenesis;GO:1902203//negative regulation of hepatocyte growth factor receptor signaling pathway;GO:1902548//negative regulation of cellular response to vascular endothelial growth factor stimulus;GO:2001113//negative regulation of cellular response to hepatocyte growth factor stimulus	--
ENSG00000151413	4.836	3.692	3.899	3.083	3.55	3.745	296	234	177	144	157	166	NUBPL	nucleotide binding protein like [Source:HGNC Symbol;Acc:HGNC:20278]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0070584//mitochondrion morphogenesis	--
ENSG00000151414	21.396	15.473	20.368	13.837	15.088	18.76	1654	1243	991	839	926	991	NEK7	NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC:13386]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20876	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0016310//phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035865//cellular response to potassium ion;GO:0051225//spindle assembly;GO:0051973//positive regulation of telomerase activity;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1904355//positive regulation of telomere capping	--
ENSG00000151418	0	0	0	0	0	0	0	0	0	0	0	0	ATP6V1G3	ATPase H+ transporting V1 subunit G3 [Source:HGNC Symbol;Acc:HGNC:18265]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0006811//ion transport;GO:1902600//proton transmembrane transport	--
ENSG00000151422	2.629	1.879	1.944	0.939	1.403	1.4	642	351	282	168	263	240	FER	FER tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3655]	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K08889	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0008157//protein phosphatase 1 binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding	GO:0000226//microtubule cytoskeleton organization;GO:0001932//regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0010591//regulation of lamellipodium assembly;GO:0010762//regulation of fibroblast migration;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030838//positive regulation of actin filament polymerization;GO:0031532//actin cytoskeleton reorganization;GO:0032496//response to lipopolysaccharide;GO:0032869//cellular response to insulin stimulus;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034614//cellular response to reactive oxygen species;GO:0035426//extracellular matrix-cell signaling;GO:0035556//intracellular signal transduction;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0036119//response to platelet-derived growth factor;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038109//Kit signaling pathway;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043304//regulation of mast cell degranulation;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0045087//innate immune response;GO:0046777//protein autophosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050904//diapedesis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070102//interleukin-6-mediated signaling pathway	--
ENSG00000151445	10.223	10.325	9.586	9.22	10.183	9.588	529	549	374	363	442	334	VIPAS39	"VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog [Source:HGNC Symbol;Acc:HGNC:20347]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:0099023//vesicle tethering complex	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0006886//intracellular protein transport;GO:0007034//vacuolar transport;GO:0007283//spermatogenesis;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0017185//peptidyl-lysine hydroxylation;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0032963//collagen metabolic process;GO:0043687//post-translational protein modification;GO:0046907//intracellular transport;GO:0090385//phagosome-lysosome fusion	--
ENSG00000151458	7.441	5.493	5.895	4.59	4.543	5.789	1297	891	725	561	697	705	ANKRD50	ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]	-	-	-	-	GO:0005768//endosome	GO:0005515//protein binding	GO:0015031//protein transport;GO:0032456//endocytic recycling	--
ENSG00000151461	3.638	2.515	2.162	1.07	1.977	2.257	390	271	172	85	179	176	UPF2	UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14327;K14327	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0035145//exon-exon junction complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001889//liver development;GO:0006406//mRNA export from nucleus;GO:0031100//animal organ regeneration"	--
ENSG00000151465	27.909	26.609	25.641	31.46	27.024	27.526	759	716	497	609	582	533	CDC123	cell division cycle 123 [Source:HGNC Symbol;Acc:HGNC:16827]	-	-	-	-	GO:0005737//cytoplasm	-	GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0045948//positive regulation of translational initiation;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:1905143//eukaryotic translation initiation factor 2 complex assembly	--
ENSG00000151466	1.921	1.904	1.217	1.461	1.258	2.108	102	100	51	49	58.08	76	SCLT1	sodium channel and clathrin linker 1 [Source:HGNC Symbol;Acc:HGNC:26406]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0071439//clathrin complex;GO:0097539//ciliary transition fiber	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0017080//sodium channel regulator activity;GO:0030276//clathrin binding	GO:0045162//clustering of voltage-gated sodium channels;GO:0060271//cilium assembly	--
ENSG00000151468	0.158	0.168	0.024	0.024	0	0.024	9	10	1	1	0	1	CCDC3	coiled-coil domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23813]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum	-	GO:0010629//negative regulation of gene expression;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0045833//negative regulation of lipid metabolic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0051055//negative regulation of lipid biosynthetic process	--
ENSG00000151470	3.482	1.917	2.787	1.348	3.613	1.775	153	95	87	59	71	68	C4orf33	chromosome 4 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:27025]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000151474	15.579	14.18	12.807	11.341	16.097	12.792	1071	1086	649	597	840	639	FRMD4A	FERM domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25491]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction	GO:0030674//protein-macromolecule adaptor activity	GO:0050709//negative regulation of protein secretion;GO:0050714//positive regulation of protein secretion;GO:0090162//establishment of epithelial cell polarity	--
ENSG00000151475	0	0	0	0	0	0	0	0	0	0	0	0	SLC25A31	solute carrier family 25 member 31 [Source:HGNC Symbol;Acc:HGNC:25319]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia	K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005757//mitochondrial permeability transition pore complex;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0046902//regulation of mitochondrial membrane permeability;GO:0055085//transmembrane transport;GO:0140021//mitochondrial ADP transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport	--
ENSG00000151490	0.972	0.749	0.455	0.635	0.395	0.826	69	37	30	29	35	19	PTPRO	protein tyrosine phosphatase receptor type O [Source:HGNC Symbol;Acc:HGNC:9678]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030027//lamellipodium;GO:0030424//axon;GO:0030426//growth cone;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0000902//cell morphogenesis;GO:0002548//monocyte chemotaxis;GO:0003093//regulation of glomerular filtration;GO:0003105//negative regulation of glomerular filtration;GO:0006470//protein dephosphorylation;GO:0007411//axon guidance;GO:0010812//negative regulation of cell-substrate adhesion;GO:0010977//negative regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0030032//lamellipodium assembly;GO:0032835//glomerulus development;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0036060//slit diaphragm assembly;GO:0050807//regulation of synapse organization;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000151491	9.13	8.506	8.73	5.535	6.368	7.784	587	532	391	301	382	332	EPS8	epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0030426//growth cone;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0032421//stereocilium bundle;GO:0032426//stereocilium tip;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035591//signaling adaptor activity	GO:0007266//Rho protein signal transduction;GO:0008344//adult locomotory behavior;GO:0008360//regulation of cell shape;GO:0010458//exit from mitosis;GO:0016601//Rac protein signal transduction;GO:0030832//regulation of actin filament length;GO:0031532//actin cytoskeleton reorganization;GO:0035023//regulation of Rho protein signal transduction;GO:0036336//dendritic cell migration;GO:0048149//behavioral response to ethanol;GO:0051016//barbed-end actin filament capping;GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0070358//actin polymerization-dependent cell motility;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:1900029//positive regulation of ruffle assembly;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000151498	10.019	10.949	12.395	12.567	10.833	10.701	418	462	375	387	391	331	ACAD8	acyl-CoA dehydrogenase family member 8 [Source:HGNC Symbol;Acc:HGNC:87]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation"	K11538;K11538	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003995//acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding"	GO:0006574//valine catabolic process;GO:0006629//lipid metabolic process;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000151500	20.112	17.924	20.714	16.949	17.259	15.531	426	376	312	268	315	244	THYN1	thymocyte nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:29560]	-	-	-	-	GO:0005634//nucleus	-	-	Others
ENSG00000151502	28.094	27.393	29.345	29.846	29.127	25.358	2015	1951.98	1492.91	1514	1761	1360	VPS26B	"VPS26, retromer complex component B [Source:HGNC Symbol;Acc:HGNC:28119]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18466	"GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030904//retromer complex;GO:0030906//retromer, cargo-selective complex;GO:0045335//phagocytic vesicle"	GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0042147//retrograde transport, endosome to Golgi;GO:0071346//cellular response to interferon-gamma"	--
ENSG00000151503	5.27	4.634	4.617	3.757	3.679	4.381	558.89	512.71	347.75	316.65	350.61	352	NCAPD3	non-SMC condensin II complex subunit D3 [Source:HGNC Symbol;Acc:HGNC:28952]	-	-	-	-	"GO:0000779//condensed chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0016020//membrane"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0042393//histone binding	GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0010032//meiotic chromosome condensation;GO:0030261//chromosome condensation;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:1905820//positive regulation of chromosome separation;GO:1905821//positive regulation of chromosome condensation	--
ENSG00000151532	5.44	5.404	6.193	4.274	4.516	5.191	459	457.95	396	271.95	325.96	327	VTI1A	vesicle transport through interaction with t-SNAREs 1A [Source:HGNC Symbol;Acc:HGNC:17792]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08493	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044306//neuron projection terminus;GO:0048471//perinuclear region of cytoplasm	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006896//Golgi to vacuole transport;GO:0006906//vesicle fusion;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016236//macroautophagy;GO:0042147//retrograde transport, endosome to Golgi;GO:0048280//vesicle fusion with Golgi apparatus;GO:0050882//voluntary musculoskeletal movement;GO:0090161//Golgi ribbon formation"	--
ENSG00000151552	23.992	24.366	27.408	25.835	27.903	24.684	720	724	610	580	707	557	QDPR	quinoid dihydropteridine reductase [Source:HGNC Symbol;Acc:HGNC:9752]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K00357;K00357	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004155//6,7-dihydropteridine reductase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0070402//NADPH binding;GO:0070404//NADH binding"	GO:0006520//cellular amino acid metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0022900//electron transport chain;GO:0051066//dihydrobiopterin metabolic process	--
ENSG00000151553	8.224	6.172	6.387	4.657	4.566	4.166	624	579	434	325	432	363	FHIP2A	FHF complex subunit HOOK interacting protein 2A [Source:HGNC Symbol;Acc:HGNC:29320]	-	-	-	-	-	-	-	--
ENSG00000151572	0.438	0.415	0.239	0.1	0.149	0.104	35	34	14	6	10	4	ANO4	anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0017128//phospholipid scramblase activity;GO:0046983//protein dimerization activity	GO:0006821//chloride transport;GO:0006869//lipid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0061588//calcium activated phospholipid scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling;GO:0061591//calcium activated galactosylceramide scrambling;GO:1902476//chloride transmembrane transport	--
ENSG00000151575	2.948	2.317	1.828	2.12	1.717	1.479	157	119.71	72.3	60.56	81	61.79	TEX9	testis expressed 9 [Source:HGNC Symbol;Acc:HGNC:29585]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000151576	7.658	7.45	8.239	7.24	9.596	9.681	556	590	455	438	594	557	QTRT2	queuine tRNA-ribosyltransferase accessory subunit 2 [Source:HGNC Symbol;Acc:HGNC:25771]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:1990234//transferase complex	GO:0005515//protein binding;GO:0008479//queuine tRNA-ribosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0101030//tRNA-guanine transglycosylation	--
ENSG00000151577	0	0.031	0	0	0	0	0	1	0	0	0	0	DRD3	dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04728//Dopaminergic synapse	K04146;K04146	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	"GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930//G protein-coupled receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0031748//D1 dopamine receptor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001963//synaptic transmission, dopaminergic;GO:0002031//G protein-coupled receptor internalization;GO:0006874//cellular calcium ion homeostasis;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007611//learning or memory;GO:0007612//learning;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell population proliferation;GO:0008542//visual learning;GO:0009410//response to xenobiotic stimulus;GO:0014059//regulation of dopamine secretion;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0032467//positive regulation of cytokinesis;GO:0032922//circadian regulation of gene expression;GO:0034776//response to histamine;GO:0035176//social behavior;GO:0035483//gastric emptying;GO:0035815//positive regulation of renal sodium excretion;GO:0040012//regulation of locomotion;GO:0042220//response to cocaine;GO:0042417//dopamine metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043266//regulation of potassium ion transport;GO:0043278//response to morphine;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0045776//negative regulation of blood pressure;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046717//acid secretion;GO:0048148//behavioral response to cocaine;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0050482//arachidonic acid secretion;GO:0050709//negative regulation of protein secretion;GO:0050883//musculoskeletal movement, spinal reflex action;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0051898//negative regulation of protein kinase B signaling;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0060134//prepulse inhibition;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0090325//regulation of locomotion involved in locomotory behavior;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1901386//negative regulation of voltage-gated calcium channel activity"	--
ENSG00000151611	3.825	2.622	2.688	1.928	2.386	2.927	250	201	161	112	124	142	MMAA	metabolism of cobalamin associated A [Source:HGNC Symbol;Acc:HGNC:18871]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016530//metallochaperone activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0009235//cobalamin metabolic process	--
ENSG00000151612	5.28	6.326	4.293	4.982	5.47	4.105	751	758	441	445	612	387	ZNF827	zinc finger protein 827 [Source:HGNC Symbol;Acc:HGNC:27193]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:1990904//ribonucleoprotein complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0120325//NuRD complex binding	"GO:0000723//telomere maintenance;GO:0006338//chromatin remodeling;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070200//establishment of protein localization to telomere;GO:1904791//negative regulation of shelterin complex assembly"	zf-C2H2
ENSG00000151615	0	0	0	0	0	0	0	0	0	0	0	0	POU4F2	POU class 4 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9219]	-	-	-	-	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031290//retinal ganglion cell axon guidance;GO:0032869//cellular response to insulin stimulus;GO:0043068//positive regulation of programmed cell death;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045773//positive regulation of axon extension;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0048675//axon extension;GO:0050885//neuromuscular process controlling balance;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0060041//retina development in camera-type eye;GO:0071345//cellular response to cytokine stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0090259//regulation of retinal ganglion cell axon guidance;GO:1902870//negative regulation of amacrine cell differentiation;GO:1904178//negative regulation of adipose tissue development;GO:1990791//dorsal root ganglion development;GO:2000679//positive regulation of transcription regulatory region DNA binding"	Pou
ENSG00000151617	0.787	0.414	0.185	0.432	0.618	0.575	47	33	8	27	43	34	EDNRA	endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Signal transduction;Signal transduction;Circulatory system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04924//Renin secretion	K04197;K04197;K04197;K04197;K04197;K04197;K04197	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071944//cell periphery	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004962//endothelin receptor activity;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001974//blood vessel remodeling;GO:0001975//response to amphetamine;GO:0002027//regulation of heart rate;GO:0003094//glomerular filtration;GO:0003207//cardiac chamber formation;GO:0003220//left ventricular cardiac muscle tissue morphogenesis;GO:0003228//atrial cardiac muscle tissue development;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0003357//noradrenergic neuron differentiation;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006939//smooth muscle contraction;GO:0007005//mitochondrion organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007411//axon guidance;GO:0007507//heart development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008217//regulation of blood pressure;GO:0008283//cell population proliferation;GO:0009611//response to wounding;GO:0010033//response to organic substance;GO:0010259//multicellular organism aging;GO:0010467//gene expression;GO:0010737//protein kinase A signaling;GO:0010827//regulation of glucose transmembrane transport;GO:0014032//neural crest cell development;GO:0014033//neural crest cell differentiation;GO:0014034//neural crest cell fate commitment;GO:0014824//artery smooth muscle contraction;GO:0016322//neuron remodeling;GO:0030202//heparin metabolic process;GO:0030878//thyroid gland development;GO:0031175//neuron projection development;GO:0032835//glomerulus development;GO:0034599//cellular response to oxidative stress;GO:0035050//embryonic heart tube development;GO:0035904//aorta development;GO:0042310//vasoconstriction;GO:0042415//norepinephrine metabolic process;GO:0042474//middle ear morphogenesis;GO:0044751//cellular response to human chorionic gonadotropin stimulus;GO:0048484//enteric nervous system development;GO:0048485//sympathetic nervous system development;GO:0048675//axon extension;GO:0048706//embryonic skeletal system development;GO:0050905//neuromuscular process;GO:0055078//sodium ion homeostasis;GO:0060070//canonical Wnt signaling pathway;GO:0060322//head development;GO:0060324//face development;GO:0060385//axonogenesis involved in innervation;GO:0061028//establishment of endothelial barrier;GO:0061626//pharyngeal arch artery morphogenesis;GO:0070294//renal sodium ion absorption;GO:0070588//calcium ion transmembrane transport;GO:0071310//cellular response to organic substance;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0071806//protein transmembrane transport;GO:0072011//glomerular endothelium development;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0086100//endothelin receptor signaling pathway;GO:0086101//endothelin receptor signaling pathway involved in heart process;GO:0097018//renal albumin absorption;GO:0097084//vascular associated smooth muscle cell development;GO:0097152//mesenchymal cell apoptotic process;GO:0097492//sympathetic neuron axon guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1903210//glomerular visceral epithelial cell apoptotic process;GO:1903537//meiotic cell cycle process involved in oocyte maturation;GO:1904888//cranial skeletal system development;GO:1905144//response to acetylcholine;GO:1905871//regulation of protein localization to cell leading edge;GO:2001259//positive regulation of cation channel activity	--
ENSG00000151623	4.625	4.341	4.135	3.713	3.371	4.668	509	524	325	298	338	359	NR3C2	nuclear receptor subfamily 3 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7979]	Organismal Systems	Excretory system	ko04960//Aldosterone-regulated sodium reabsorption	K08555	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0043235//receptor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling"	ESR-like
ENSG00000151632	0.13	0	0.139	0.262	0.616	0.089	4	0	2	3	14	1	AKR1C2	aldo-keto reductase family 1 member C2 [Source:HGNC Symbol;Acc:HGNC:385]	Human Diseases;Human Diseases;Metabolism	Cancer: overview;Cancer: overview;Lipid metabolism	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05204//Chemical carcinogenesis - DNA adducts;ko00140//Steroid hormone biosynthesis	K00089;K00089;K00089	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0031406//carboxylic acid binding;GO:0032052//bile acid binding;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047023//androsterone dehydrogenase activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047718//indanol dehydrogenase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007586//digestion;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0030855//epithelial cell differentiation;GO:0042448//progesterone metabolic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0071395//cellular response to jasmonic acid stimulus;GO:0071799//cellular response to prostaglandin D stimulus	--
ENSG00000151640	3.424	3.678	2.94	2.783	2.555	2.656	186	201	120	112	114	95	DPYSL4	dihydropyrimidinase like 4 [Source:HGNC Symbol;Acc:HGNC:3016]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0031005//filamin binding"	GO:0007399//nervous system development;GO:0070997//neuron death;GO:0097485//neuron projection guidance	--
ENSG00000151650	0	0	0	0	0	0	0	0	0	0	0	0	VENTX	VENT homeobox [Source:HGNC Symbol;Acc:HGNC:13639]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000151651	0.104	0.452	0.485	0.16	0.333	0.354	7	9	9	8	19	17	ADAM8	ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215]	-	-	-	-	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032010//phagolysosome;GO:0032127//dense core granule membrane;GO:0035579//specific granule membrane;GO:0042581//specific granule;GO:0070820//tertiary granule;GO:0070821//tertiary granule membrane;GO:0071133//alpha9-beta1 integrin-ADAM8 complex;GO:0101003//ficolin-1-rich granule membrane	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	GO:0000902//cell morphogenesis;GO:0001525//angiogenesis;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002675//positive regulation of acute inflammatory response;GO:0002693//positive regulation of cellular extravasation;GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:0010954//positive regulation of protein processing;GO:0022407//regulation of cell-cell adhesion;GO:0022617//extracellular matrix disassembly;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0043406//positive regulation of MAP kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0045089//positive regulation of innate immune response;GO:0045780//positive regulation of bone resorption;GO:0045785//positive regulation of cell adhesion;GO:0048247//lymphocyte chemotaxis;GO:0050714//positive regulation of protein secretion;GO:0050729//positive regulation of inflammatory response;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0071456//cellular response to hypoxia;GO:0098609//cell-cell adhesion;GO:2000309//positive regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:2000391//positive regulation of neutrophil extravasation;GO:2000406//positive regulation of T cell migration;GO:2000415//positive regulation of fibronectin-dependent thymocyte migration;GO:2000418//positive regulation of eosinophil migration	--
ENSG00000151655	0	0	0	0	0	0	0	0	0	0	0	0	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:6167]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process	--
ENSG00000151657	1.524	1.313	1.16	1.565	1.369	1.479	201	155	113	137	122	142	KIN	Kin17 DNA and RNA binding protein [Source:HGNC Symbol;Acc:HGNC:6327]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006397//mRNA processing;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000151665	16.456	14.776	14.861	12.946	14.075	16.643	428.24	386.77	293.08	250.86	309.36	320.9	PIGF	phosphatidylinositol glycan anchor biosynthesis class F [Source:HGNC Symbol;Acc:HGNC:8962]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05287;K05287	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004307//ethanolaminephosphotransferase activity;GO:0005515//protein binding;GO:0051377//mannose-ethanolamine phosphotransferase activity	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000151687	0.262	0.213	0.07	0.222	0.122	0.173	21	17	4	13	8	10	ANKAR	ankyrin and armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:26350]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000151689	8.092	6.14	9.785	8.455	8.371	9.318	280	236	250	233	262	254	INPP1	inositol polyphosphate-1-phosphatase [Source:HGNC Symbol;Acc:HGNC:6071]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01107;K01107;K01107	GO:0005829//cytosol	"GO:0004441//inositol-1,4-bisphosphate 1-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation	--
ENSG00000151690	3.083	2.869	2.409	1.695	2.651	2.096	275	257	159	120	148	129	MFSD6	major facilitator superfamily domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24711]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0055085//transmembrane transport	--
ENSG00000151692	3.532	3.321	3.401	3.379	3.741	4.17	419	396.03	298	297	375	360	RNF144A	ring finger protein 144A [Source:HGNC Symbol;Acc:HGNC:20457]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000151693	7.495	6.93	5.132	4.068	4.78	4.669	874.07	810.81	443.12	352.91	470.25	397.04	ASAP2	"ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:HGNC:2721]"	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04144//Endocytosis;ko04666//Fc gamma R-mediated phagocytosis	K12488;K12488	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0043547//positive regulation of GTPase activity	--
ENSG00000151694	11.549	10.357	9.865	7.911	8.099	10.771	932.75	889.19	594.4	489.35	575.16	639.86	ADAM17	ADAM metallopeptidase domain 17 [Source:HGNC Symbol;Acc:HGNC:195]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Signal transduction	ko05010//Alzheimer disease;ko05171//Coronavirus disease - COVID-19;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04330//Notch signaling pathway	K06059;K06059;K06059;K06059	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032587//ruffle membrane;GO:0045121//membrane raft	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005112//Notch binding;GO:0005138//interleukin-6 receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0030165//PDZ domain binding;GO:0046872//metal ion binding;GO:1902945//metalloendopeptidase activity involved in amyloid precursor protein catabolic process	"GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0002446//neutrophil mediated immunity;GO:0002467//germinal center formation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0007155//cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010820//positive regulation of T cell chemotaxis;GO:0016485//protein processing;GO:0030183//B cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032722//positive regulation of chemokine production;GO:0033025//regulation of mast cell apoptotic process;GO:0033077//T cell differentiation in thymus;GO:0033627//cell adhesion mediated by integrin;GO:0035313//wound healing, spreading of epidermal cells;GO:0035624//receptor transactivation;GO:0042987//amyloid precursor protein catabolic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0048536//spleen development;GO:0048870//cell motility;GO:0050830//defense response to Gram-positive bacterium;GO:0050896//response to stimulus;GO:0051272//positive regulation of cellular component movement;GO:0071403//cellular response to high density lipoprotein particle stimulus;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1905564//positive regulation of vascular endothelial cell proliferation"	--
ENSG00000151702	0.157	0.414	0	0	0.128	0.026	11	15	0	0	7	1	FLI1	"Fli-1 proto-oncogene, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3749]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09436	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007599//hemostasis;GO:0008015//blood circulation;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0035855//megakaryocyte development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000151704	0	0	0	0	0	0	0	0	0	0	0	0	KCNJ1	potassium inwardly rectifying channel subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:6255]	Organismal Systems;Organismal Systems	Digestive system;Excretory system	ko04971//Gastric acid secretion;ko04960//Aldosterone-regulated sodium reabsorption	K04995;K04995	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0015272//ATP-activated inward rectifier potassium channel activity"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000151715	0.678	0.303	0.905	0.69	0.47	0.783	31	12	26	19	16	21	TMEM45B	transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000151718	28.387	21.818	21.575	16.574	16.092	24.355	3409	2569	1921	1442	1663	1924	WWC2	WW and C2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24148]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019900//kinase binding;GO:0060090//molecular adaptor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0016477//cell migration;GO:0035330//regulation of hippo signaling;GO:0035331//negative regulation of hippo signaling;GO:0046621//negative regulation of organ growth"	--
ENSG00000151725	2.87	1.868	1.861	1.613	1.518	1.593	123.42	83.65	61.6	52.4	52.22	46.3	CENPU	centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite"	GO:0005515//protein binding	GO:0043009//chordate embryonic development	--
ENSG00000151726	68.942	64.985	72.595	71.875	68.493	79.936	4876	4742	3848	3802	4138	4142	ACSL1	acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569]	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0050197//phytanate-CoA ligase activity;GO:0070251//pristanate-CoA ligase activity;GO:0090434//oleoyl-CoA ligase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0007584//response to nutrient;GO:0008610//lipid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010747//positive regulation of long-chain fatty acid import across plasma membrane;GO:0014070//response to organic cyclic compound;GO:0015908//fatty acid transport;GO:0019432//triglyceride biosynthetic process;GO:0033211//adiponectin-activated signaling pathway;GO:0034201//response to oleic acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042178//xenobiotic catabolic process;GO:0044539//long-chain fatty acid import into cell;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000151729	31.639	28.127	29.558	32.396	30.155	33.492	1740	1621	1302	1291	1449	1439	SLC25A4	solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia	K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005757//mitochondrial permeability transition pore complex;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032592//integral component of mitochondrial membrane	GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0015207//adenine transmembrane transporter activity;GO:0015297//antiporter activity;GO:0017077//oxidative phosphorylation uncoupler activity	GO:0000002//mitochondrial genome maintenance;GO:0006091//generation of precursor metabolites and energy;GO:0008637//apoptotic mitochondrial changes;GO:0015853//adenine transport;GO:0015866//ADP transport;GO:0046902//regulation of mitochondrial membrane permeability;GO:0055085//transmembrane transport;GO:0060546//negative regulation of necroptotic process;GO:0140021//mitochondrial ADP transmembrane transport;GO:1901526//positive regulation of mitophagy;GO:1902600//proton transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport;GO:1990845//adaptive thermogenesis	--
ENSG00000151743	10.935	8.096	9.802	10.494	8.096	9.678	293.12	259.31	204.55	212.82	194.5	217.88	AMN1	antagonist of mitotic exit network 1 homolog [Source:HGNC Symbol;Acc:HGNC:27281]	-	-	-	-	GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000151746	5	4.989	4.296	4.006	5.519	4.617	480	427	239	254	339	249	BICD1	BICD cargo adaptor 1 [Source:HGNC Symbol;Acc:HGNC:1049]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0099503//secretory vesicle	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0031871//proteinase activated receptor binding;GO:0034452//dynactin binding;GO:0045505//dynein intermediate chain binding;GO:0070840//dynein complex binding	GO:0006396//RNA processing;GO:0008298//intracellular mRNA localization;GO:0009653//anatomical structure morphogenesis;GO:0016032//viral process;GO:0033365//protein localization to organelle;GO:0034063//stress granule assembly;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0072393//microtubule anchoring at microtubule organizing center;GO:1900275//negative regulation of phospholipase C activity;GO:1900276//regulation of proteinase activated receptor activity;GO:1900737//negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway;GO:1904781//positive regulation of protein localization to centrosome	--
ENSG00000151748	26.144	21.923	25.536	19.316	20.386	23.366	1675.51	1378.28	1208.49	905.73	1104.54	1089.51	SAV1	salvador family WW domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:17795]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16686;K16686	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0030425//dendrite	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0031697//beta-1 adrenergic receptor binding;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0060090//molecular adaptor activity;GO:0070699//type II activin receptor binding	GO:0001942//hair follicle development;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0030216//keratinocyte differentiation;GO:0035329//hippo signaling;GO:0042127//regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043113//receptor clustering;GO:0045600//positive regulation of fat cell differentiation;GO:0046620//regulation of organ growth;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060412//ventricular septum morphogenesis;GO:0060487//lung epithelial cell differentiation;GO:0060575//intestinal epithelial cell differentiation;GO:2000036//regulation of stem cell population maintenance	--
ENSG00000151773	0.499	0.398	0.095	0.519	0.443	0.193	12	17.09	3	13	16	6	CCDC122	coiled-coil domain containing 122 [Source:HGNC Symbol;Acc:HGNC:26478]	-	-	-	-	-	-	-	--
ENSG00000151778	4.091	3.841	4.928	4.41	5.622	4.597	80	76	70	63	90	65	SERP2	stress associated endoplasmic reticulum protein family member 2 [Source:HGNC Symbol;Acc:HGNC:20607]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006486//protein glycosylation;GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response	--
ENSG00000151779	17.322	17.546	13.716	11.117	13.546	12.849	2239	2116	1463	1229	1483	1280	NBAS	NBAS subunit of NRZ tethering complex [Source:HGNC Symbol;Acc:HGNC:15625]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070939//Dsl1/NZR complex	GO:0000149//SNARE binding;GO:0005515//protein binding	"GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000151789	2.631	1.237	1.452	0.792	1.418	1.222	359.09	189.1	135.51	89.32	100.61	116.28	ZNF385D	zinc finger protein 385D [Source:HGNC Symbol;Acc:HGNC:26191]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	-	--
ENSG00000151790	0	0	0	0.038	0.101	0	0	0	0	1	3	0	TDO2	"tryptophan 2,3-dioxygenase [Source:HGNC Symbol;Acc:HGNC:11708]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K00453;K00453	GO:0005829//cytosol	"GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016597//amino acid binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006568//tryptophan metabolic process;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0019442//tryptophan catabolic process to acetyl-CoA;GO:0051289//protein homotetramerization;GO:1904842//response to nitroglycerin	--
ENSG00000151806	6.322	4.284	4.255	4.248	4.451	4.611	481	359.24	257	243	325	263	GUF1	GTP binding elongation factor GUF1 [Source:HGNC Symbol;Acc:HGNC:25799]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0043022//ribosome binding;GO:0097177//mitochondrial ribosome binding	GO:0006412//translation;GO:0045727//positive regulation of translation	--
ENSG00000151812	0	0	0	0	0	0	0	0	0	0	0	0	SLC35F4	solute carrier family 35 member F4 [Source:HGNC Symbol;Acc:HGNC:19845]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000151834	0.132	0	0.028	0.12	0.102	0.242	8	0	1	12	10	10	GABRA2	gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001505//regulation of neurotransmitter levels;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006836//neurotransmitter transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport;GO:1904862//inhibitory synapse assembly"	--
ENSG00000151835	3.826	1.791	1.54	1.151	1.516	1.627	1205	568	312	268	395	352	SACS	sacsin molecular chaperone [Source:HGNC Symbol;Acc:HGNC:10519]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0030424//axon;GO:0030425//dendrite;GO:0070852//cell body fiber	GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0051087//chaperone binding;GO:0070628//proteasome binding	GO:0006457//protein folding;GO:0090084//negative regulation of inclusion body assembly	--
ENSG00000151838	0.039	0	0	0	0.023	0	2	0	0	0	1	0	CCDC175	coiled-coil domain containing 175 [Source:HGNC Symbol;Acc:HGNC:19847]	-	-	-	-	-	-	-	--
ENSG00000151846	0.093	0.108	0.042	0.042	0	0	6	7	2	2	0	0	PABPC3	poly(A) binding protein cytoplasmic 3 [Source:HGNC Symbol;Acc:HGNC:8556]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	GO:0016071//mRNA metabolic process	--
ENSG00000151849	0.608	0.368	0.471	0.243	0.214	0.276	55	33	31	19	18	19	CENPJ	centromere protein J [Source:HGNC Symbol;Acc:HGNC:17272]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0008275//gamma-tubulin small complex;GO:0036064//ciliary basal body;GO:0120099//procentriole replication complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0043015//gamma-tubulin binding	"GO:0007020//microtubule nucleation;GO:0007099//centriole replication;GO:0007224//smoothened signaling pathway;GO:0030954//astral microtubule nucleation;GO:0044458//motile cilium assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046599//regulation of centriole replication;GO:0046601//positive regulation of centriole replication;GO:0046785//microtubule polymerization;GO:0051298//centrosome duplication;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0060271//cilium assembly;GO:0061511//centriole elongation;GO:0098534//centriole assembly;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902857//positive regulation of non-motile cilium assembly;GO:1903724//positive regulation of centriole elongation;GO:1904951//positive regulation of establishment of protein localization;GO:1905515//non-motile cilium assembly;GO:1905832//positive regulation of spindle assembly"	--
ENSG00000151876	3.492	3.505	2.803	2.295	2.803	2.214	99	102	65	51	78	46	FBXO4	F-box protein 4 [Source:HGNC Symbol;Acc:HGNC:13583]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10291	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0000723//telomere maintenance;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007568//aging;GO:0010608//posttranscriptional regulation of gene expression;GO:0016567//protein ubiquitination;GO:0019725//cellular homeostasis;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035726//common myeloid progenitor cell proliferation;GO:0048147//negative regulation of fibroblast proliferation;GO:0071479//cellular response to ionizing radiation;GO:1900181//negative regulation of protein localization to nucleus;GO:1902916//positive regulation of protein polyubiquitination;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000151881	3.532	2.733	2.912	3.74	4.153	4.188	166	123	97	104	127	139	TMEM267	transmembrane protein 267 [Source:HGNC Symbol;Acc:HGNC:26139]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000151882	1.274	0.788	0.815	1.205	0.768	0.655	58	38	28	37	30	28	CCL28	C-C motif chemokine ligand 28 [Source:HGNC Symbol;Acc:HGNC:17700]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04672//Intestinal immune network for IgA production;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05513;K05513;K05513;K05513	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity	GO:0001954//positive regulation of cell-matrix adhesion;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007584//response to nutrient;GO:0060326//cell chemotaxis;GO:1903237//negative regulation of leukocyte tethering or rolling	--
ENSG00000151883	6.765	6.088	5.189	5.545	5.146	5.312	462	327	242	218	263	228	PARP8	poly(ADP-ribose) polymerase family member 8 [Source:HGNC Symbol;Acc:HGNC:26124]	-	-	-	-	-	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:1990404//protein ADP-ribosylase activity	GO:0006471//protein ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000151892	4.658	6.24	4.612	5.728	5.309	4.929	568	733	469	559	611	404	GFRA1	GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243]	-	-	-	-	GO:0005615//extracellular space;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0070062//extracellular exosome;GO:0098797//plasma membrane protein complex	GO:0005030//neurotrophin receptor activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0038023//signaling receptor activity	GO:0001822//kidney development;GO:0007166//cell surface receptor signaling pathway;GO:0007399//nervous system development;GO:0007568//aging;GO:0008584//male gonad development;GO:0016477//cell migration;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0038179//neurotrophin signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation	--
ENSG00000151893	9.92	8.287	10.621	9.72	8.737	9.401	1591	1269	1076	1014	1109	1137	CACUL1	CDK2 associated cullin domain 1 [Source:HGNC Symbol;Acc:HGNC:23727]	-	-	-	-	-	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0045860//positive regulation of protein kinase activity	--
ENSG00000151914	6.049	3.942	2.426	2.538	3.115	2.937	966	542	317	281	433	283	DST	dystonin [Source:HGNC Symbol;Acc:HGNC:1090]	-	-	-	-	GO:0005604//basement membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0009925//basal plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0030424//axon;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle;GO:0031673//H zone;GO:0035371//microtubule plus-end;GO:0042995//cell projection;GO:0110165//cellular anatomical entity;GO:1904115//axon cytoplasm	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0051010//microtubule plus-end binding	GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008090//retrograde axonal transport;GO:0009611//response to wounding;GO:0030011//maintenance of cell polarity;GO:0031122//cytoplasmic microtubule organization;GO:0031581//hemidesmosome assembly;GO:0042060//wound healing;GO:0045104//intermediate filament cytoskeleton organization;GO:0048870//cell motility	--
ENSG00000151917	0.33	0.243	0.196	0.271	0.287	0.449	22	14	10	11	14	15	BEND6	BEN domain containing 6 [Source:HGNC Symbol;Acc:HGNC:20871]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity	"GO:0007399//nervous system development;GO:0045666//positive regulation of neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000151923	14.424	14.057	23.428	14.567	12.782	14.936	1071	1038	817	737	753	826	TIAL1	TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11804]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0010494//cytoplasmic stress granule;GO:0044194//cytolytic granule	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:1903231//mRNA binding involved in posttranscriptional gene silencing	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006952//defense response;GO:0007281//germ cell development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0016441//posttranscriptional gene silencing;GO:0017145//stem cell division;GO:0035332//positive regulation of hippo signaling;GO:2000637//positive regulation of gene silencing by miRNA	--
ENSG00000151929	12.227	13.425	12.319	11.021	12.046	10.383	621	669	478	400	512	399	BAG3	BAG cochaperone 3 [Source:HGNC Symbol;Acc:HGNC:939]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016235//aggresome;GO:0030018//Z disc;GO:0043005//neuron projection;GO:0101031//chaperone complex	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0045505//dynein intermediate chain binding;GO:0051087//chaperone binding;GO:0140597//protein carrier activity	GO:0000045//autophagosome assembly;GO:0006457//protein folding;GO:0006915//apoptotic process;GO:0007420//brain development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0021510//spinal cord development;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0042307//positive regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0046716//muscle cell cellular homeostasis;GO:0046827//positive regulation of protein export from nucleus;GO:0050821//protein stabilization;GO:0061684//chaperone-mediated autophagy;GO:0070842//aggresome assembly;GO:0071260//cellular response to mechanical stimulus;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:0098840//protein transport along microtubule;GO:1903215//negative regulation of protein targeting to mitochondrion;GO:1905337//positive regulation of aggrephagy	--
ENSG00000151948	3.106	3.326	2.833	2.282	2.68	2.687	189	199	130	104	133	111	GLT1D1	glycosyltransferase 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26483]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	-	--
ENSG00000151952	0.079	0.156	0.181	0.371	0.474	0.648	10	20	17	35	51	60	TMEM132D	transmembrane protein 132D [Source:HGNC Symbol;Acc:HGNC:29411]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000151962	0.154	0.083	0.028	0.134	0.11	0.085	8	4	1	6	7	4	RBM46	RNA binding motif protein 46 [Source:HGNC Symbol;Acc:HGNC:28401]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0001829//trophectodermal cell differentiation;GO:0048255//mRNA stabilization	--
ENSG00000151967	14.293	14.306	14.313	10.413	12.744	12.841	482.64	492.54	349.77	263.49	363.46	319.12	SCHIP1	schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0030054//cell junction	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0035332//positive regulation of hippo signaling	--
ENSG00000152034	0.037	0.042	0.052	0	0.015	0.053	1	2	3	0	1	3	MCHR2	melanin concentrating hormone receptor 2 [Source:HGNC Symbol;Acc:HGNC:20867]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05054	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000152049	1.141	1.464	0.717	0.603	1.175	0.841	69	89	32	27	60	37	KCNE4	potassium voltage-gated channel subfamily E regulatory subunit 4 [Source:HGNC Symbol;Acc:HGNC:6244]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086011//membrane repolarization during action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1902260//negative regulation of delayed rectifier potassium channel activity	--
ENSG00000152056	1.147	1.814	0.675	2.583	4.737	2.381	85.8	97.45	35.17	77.96	108.17	78.31	AP1S3	adaptor related protein complex 1 subunit sigma 3 [Source:HGNC Symbol;Acc:HGNC:18971]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12395;K12395	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030121//AP-1 adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000152061	51.438	42.446	41.071	28.969	33.018	31.549	5268	4647	3217	2232	2979	2447	RABGAP1L	RAB GTPase activating protein 1 like [Source:HGNC Symbol;Acc:HGNC:24663]	-	-	-	-	GO:0005634//nucleus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0032880//regulation of protein localization;GO:0090630//activation of GTPase activity	--
ENSG00000152076	11.95	14.044	11.712	9.46	7.905	11.279	228.27	281.12	199.63	145.19	144.37	157.39	CCDC74B	coiled-coil domain containing 74B [Source:HGNC Symbol;Acc:HGNC:25267]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000152078	12.262	9.427	10.81	10.263	9.278	12.218	1730.71	1337.49	1126.95	1046.19	1080.72	1191.22	TLCD4	TLC domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26477]	-	-	-	-	GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0055088//lipid homeostasis	--
ENSG00000152082	68.147	74.488	74.965	96.094	82.765	78.38	836.7	925.94	680	863.42	857.23	703.69	MZT2B	mitotic spindle organizing protein 2B [Source:HGNC Symbol;Acc:HGNC:25886]	-	-	-	-	GO:0000931//gamma-tubulin large complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000152086	0	0	0.043	0	0	0	0	0	1	0	0	0	TUBA3E	tubulin alpha 3e [Source:HGNC Symbol;Acc:HGNC:20765]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0008150//biological_process	--
ENSG00000152092	3.986	4.903	3.708	4.717	5.039	5.201	507	597	334	469	511	459	ASTN1	astrotactin 1 [Source:HGNC Symbol;Acc:HGNC:773]	-	-	-	-	GO:0005575//cellular_component;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043204//perikaryon	GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007626//locomotory behavior;GO:0016477//cell migration;GO:0098609//cell-cell adhesion	--
ENSG00000152093	0	0	0	0	0	0	0	0	0	0	0	0	CFC1B	"cripto, FRL-1, cryptic family 1B [Source:HGNC Symbol;Acc:HGNC:33983]"	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0005102//signaling receptor binding;GO:0038100//nodal binding;GO:0070697//activin receptor binding	GO:0001568//blood vessel development;GO:0007368//determination of left/right symmetry;GO:0007369//gastrulation;GO:0007507//heart development;GO:0009952//anterior/posterior pattern specification;GO:0038092//nodal signaling pathway;GO:0048856//anatomical structure development	--
ENSG00000152102	22.398	21.136	19.86	19.831	20.432	22.844	2525	2395	1653	1656	1946	1872	FAM168B	family with sequence similarity 168 member B [Source:HGNC Symbol;Acc:HGNC:27016]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	-	-	--
ENSG00000152104	9.447	9.887	9.024	7.751	8.944	7.577	2561	2593	1772	1591	2094	1458	PTPN14	protein tyrosine phosphatase non-receptor type 14 [Source:HGNC Symbol;Acc:HGNC:9647]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003712//transcription coregulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030971//receptor tyrosine kinase binding	"GO:0001946//lymphangiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046825//regulation of protein export from nucleus"	--
ENSG00000152127	12.082	11.741	14.247	13.763	13.471	16.734	2068	2020	1801	1745	1948	2084	MGAT5	"alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7049]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K00744;K00744	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0004864//protein phosphatase inhibitor activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity;GO:0030145//manganese ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019082//viral protein processing;GO:0030335//positive regulation of cell migration;GO:1903614//negative regulation of protein tyrosine phosphatase activity;GO:1904894//positive regulation of receptor signaling pathway via STAT	--
ENSG00000152128	0.051	0.203	0	0.206	0.09	0.175	2	8	0	6	3	5	TMEM163	transmembrane protein 163 [Source:HGNC Symbol;Acc:HGNC:25380]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0045202//synapse	GO:0008270//zinc ion binding	GO:0099180//zinc ion import into synaptic vesicle	--
ENSG00000152133	2.983	2.486	2.313	2.272	2.185	2.106	237	199	136	134	147	122	GPATCH11	G-patch domain containing 11 [Source:HGNC Symbol;Acc:HGNC:26768]	-	-	-	-	GO:0000776//kinetochore	GO:0003676//nucleic acid binding	-	--
ENSG00000152137	126.48	133.968	144.431	149.826	134.735	152.068	4879	5196	4117	4276	4394	4271	HSPB8	heat shock protein family B (small) member 8 [Source:HGNC Symbol;Acc:HGNC:30171]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0034620//cellular response to unfolded protein;GO:1905337//positive regulation of aggrephagy	--
ENSG00000152147	3.911	4.551	5.181	4.747	3.385	5.444	162	165	128	155	124	139	GEMIN6	gem nuclear organelle associated protein 6 [Source:HGNC Symbol;Acc:HGNC:20044]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies	GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000152154	2.307	1.945	1.728	3.6	2.6	1.9	77	67	43	90	75	47	TMEM178A	transmembrane protein 178A [Source:HGNC Symbol;Acc:HGNC:28517]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0045671//negative regulation of osteoclast differentiation;GO:0051480//regulation of cytosolic calcium ion concentration	--
ENSG00000152192	0	0	0	0	0	0	0	0	0	0	0	0	POU4F1	POU class 4 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9218]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0051020//GTPase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001967//suckling behavior;GO:0003223//ventricular compact myocardium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0021535//cell migration in hindbrain;GO:0021559//trigeminal nerve development;GO:0021953//central nervous system neuron differentiation;GO:0021986//habenula development;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0043524//negative regulation of neuron apoptotic process;GO:0045672//positive regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048665//neuron fate specification;GO:0048880//sensory system development;GO:0048934//peripheral nervous system neuron differentiation;GO:0048935//peripheral nervous system neuron development;GO:0050767//regulation of neurogenesis;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051355//proprioception involved in equilibrioception;GO:0051726//regulation of cell cycle;GO:0060384//innervation;GO:0071345//cellular response to cytokine stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:2000679//positive regulation of transcription regulatory region DNA binding"	Pou
ENSG00000152193	6.2	5.361	4.542	3.675	4.995	3.552	451	392	244	198	307	188	OBI1	ORC ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:20308]	-	-	-	-	GO:0000785//chromatin;GO:0005694//chromosome	GO:0003682//chromatin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006275//regulation of DNA replication;GO:0006513//protein monoubiquitination;GO:0051865//protein autoubiquitination	--
ENSG00000152207	0.289	0.196	0.126	0.153	0.195	0.241	28	17	9	11	16	17	CYSLTR2	cysteinyl leukotriene receptor 2 [Source:HGNC Symbol;Acc:HGNC:18274]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04323;K04323	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001631//cysteinyl leukotriene receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004974//leukotriene receptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0050790//regulation of catalytic activity;GO:0061737//leukotriene signaling pathway;GO:0071377//cellular response to glucagon stimulus	--
ENSG00000152208	0.279	0.282	0.465	1.24	1.403	1.246	27	27	34	100	105	96	GRID2	glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04730//Long-term depression	K05207;K05207	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0036477//somatodendritic compartment;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:0110165//cellular anatomical entity	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0030165//PDZ domain binding;GO:0038023//signaling receptor activity;GO:0097110//scaffold protein binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007215//glutamate receptor signaling pathway;GO:0010975//regulation of neuron projection development;GO:0021707//cerebellar granule cell differentiation;GO:0034220//ion transmembrane transport;GO:0034613//cellular protein localization;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0043523//regulation of neuron apoptotic process;GO:0050804//modulation of chemical synaptic transmission;GO:0051965//positive regulation of synapse assembly;GO:0060079//excitatory postsynaptic potential;GO:0060134//prepulse inhibition;GO:0099151//regulation of postsynaptic density assembly;GO:1900454//positive regulation of long-term synaptic depression;GO:1904861//excitatory synapse assembly"	--
ENSG00000152213	0	0	0	0	0	0	0	0	0	0	0	0	ARL11	ADP ribosylation factor like GTPase 11 [Source:HGNC Symbol;Acc:HGNC:24046]	-	-	-	-	GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000152214	0	0	0	0	0	0	0	0	0	0	0	0	RIT2	Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045121//membrane raft;GO:0045202//synapse;GO:0097447//dendritic tree	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0030215//semaphorin receptor binding	GO:0001932//regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007268//chemical synaptic transmission;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0030100//regulation of endocytosis;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0032507//maintenance of protein location in cell;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050848//regulation of calcium-mediated signaling	--
ENSG00000152217	0.392	0.508	0.292	0.194	0.386	0.209	80	77	44	29	61	31	SETBP1	SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding	-	Others
ENSG00000152219	8.016	7.068	7.375	6.028	5.563	7.291	403	352	271	224	235	264	ARL14EP	ADP ribosylation factor like GTPase 14 effector protein [Source:HGNC Symbol;Acc:HGNC:26798]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000152223	5.764	5.959	5.756	4.994	5.783	6.515	1330	1401	1007	862	1156	961	EPG5	ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0006862//nucleotide transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0032456//endocytic recycling;GO:0034162//toll-like receptor 9 signaling pathway;GO:0097352//autophagosome maturation;GO:1990786//cellular response to dsDNA	--
ENSG00000152229	0.498	0.448	0.479	0.607	0.913	0.641	31	28	22	28	48	29	PSTPIP2	proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003779//actin binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0016477//cell migration;GO:0030041//actin filament polymerization	--
ENSG00000152234	248.286	245.148	256.466	285.554	261.779	277.535	9979	9904	7610	8491	8889	8119	ATP5F1A	ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02132;K02132;K02132;K02132;K02132;K02132;K02132;K02132;K02132;K02132;K02132	"GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1);GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0009986//cell surface;GO:0016020//membrane;GO:0045121//membrane raft;GO:0045259//proton-transporting ATP synthase complex;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0070062//extracellular exosome"	"GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0032559//adenyl ribonucleotide binding;GO:0042288//MHC class I protein binding;GO:0043531//ADP binding;GO:0043532//angiostatin binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0001937//negative regulation of endothelial cell proliferation;GO:0006629//lipid metabolic process;GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0007568//aging;GO:0014850//response to muscle activity;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045471//response to ethanol;GO:0046034//ATP metabolic process;GO:0071549//cellular response to dexamethasone stimulus;GO:0071732//cellular response to nitric oxide;GO:1902600//proton transmembrane transport	--
ENSG00000152240	6.521	5.07	6.753	5.976	5.322	5.192	145	111	105	91	100	84	HAUS1	HAUS augmin like complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:25174]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000152242	4.934	5.141	5.514	3.854	4.39	5.845	485	523	424	312	405	422	C18orf25	chromosome 18 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:28172]	-	-	-	-	-	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000152253	0.287	0.25	0.098	0.194	0.085	0.099	8	7	2.01	4	2	2	SPC25	SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005829//cytosol;GO:0031262//Ndc80 complex;GO:0031617//NMS complex"	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051301//cell division	--
ENSG00000152254	0	0	0	0	0	0	0	0	0	0	0	0	G6PC2	glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906]	Metabolism;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Carbohydrate metabolism;Endocrine system;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko04920//Adipocytokine signaling pathway;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084;K01084	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004346//glucose-6-phosphatase activity;GO:0016787//hydrolase activity	GO:0006094//gluconeogenesis;GO:0016311//dephosphorylation;GO:0042593//glucose homeostasis;GO:0050796//regulation of insulin secretion;GO:0051156//glucose 6-phosphate metabolic process	--
ENSG00000152256	3.463	4.174	3.524	3.215	2.794	2.161	312	299	177	157	198	142	PDK1	pyruvate dehydrogenase kinase 1 [Source:HGNC Symbol;Acc:HGNC:8809]	Environmental Information Processing;Human Diseases	Signal transduction;Cancer: overview	ko04066//HIF-1 signaling pathway;ko05230//Central carbon metabolism in cancer	K12077;K12077	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006468//protein phosphorylation;GO:0008283//cell population proliferation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0010906//regulation of glucose metabolic process;GO:0016310//phosphorylation;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway	--
ENSG00000152266	0	0.061	0	0	0.072	0	0	1	0	0	1	0	PTH	parathyroid hormone [Source:HGNC Symbol;Acc:HGNC:9606]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Immune disease;Endocrine system;Excretory system	"ko04080//Neuroactive ligand-receptor interaction;ko05323//Rheumatoid arthritis;ko04928//Parathyroid hormone synthesis, secretion and action;ko04961//Endocrine and other factor-regulated calcium reabsorption"	K05261;K05261;K05261;K05261	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031856//parathyroid hormone receptor binding;GO:0031857//type 1 parathyroid hormone receptor binding;GO:0047485//protein N-terminus binding;GO:0048018//receptor ligand activity;GO:0051428//peptide hormone receptor binding	GO:0001501//skeletal system development;GO:0006874//cellular calcium ion homeostasis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007266//Rho protein signal transduction;GO:0007267//cell-cell signaling;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0009410//response to xenobiotic stimulus;GO:0009967//positive regulation of signal transduction;GO:0010288//response to lead ion;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010960//magnesium ion homeostasis;GO:0030282//bone mineralization;GO:0030501//positive regulation of bone mineralization;GO:0031667//response to nutrient levels;GO:0032331//negative regulation of chondrocyte differentiation;GO:0033280//response to vitamin D;GO:0034645//cellular macromolecule biosynthetic process;GO:0045453//bone resorption;GO:0045471//response to ethanol;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045778//positive regulation of ossification;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046058//cAMP metabolic process;GO:0046326//positive regulation of glucose import;GO:0046686//response to cadmium ion;GO:0048873//homeostasis of number of cells within a tissue;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0071107//response to parathyroid hormone;GO:0071774//response to fibroblast growth factor;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0071866//negative regulation of apoptotic process in bone marrow cell;GO:0090290//positive regulation of osteoclast proliferation;GO:1900158//negative regulation of bone mineralization involved in bone maturation	--
ENSG00000152270	0.393	0.28	0.314	0.445	0.324	0.387	43	35	26	41	34	35	PDE3B	phosphodiesterase 3B [Source:HGNC Symbol;Acc:HGNC:8779]	Metabolism;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Metabolism;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Nucleotide metabolism;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Endocrine system	ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko00230//Purine metabolism;ko04914//Progesterone-mediated oocyte maturation;ko04922//Glucagon signaling pathway;ko05032//Morphine addiction;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K13296;K13296;K13296;K13296;K13296;K13296;K13296;K13296;K13296;K13296;K13296	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032045//guanyl-nucleotide exchange factor complex	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004119//cGMP-inhibited cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0043422//protein kinase B binding;GO:0046872//metal ion binding"	GO:0001525//angiogenesis;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0032869//cellular response to insulin stimulus;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0050995//negative regulation of lipid catabolic process	--
ENSG00000152284	9.238	9.352	9.906	10.183	11.986	10.766	572	582	453	467	627	485	TCF7L1	transcription factor 7 like 1 [Source:HGNC Symbol;Acc:HGNC:11640]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Cancer: specific types;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05132//Salmonella infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04936//Alcoholic liver disease;ko04916//Melanogenesis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05221//Acute myeloid leukemia;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490;K04490	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:1990907//beta-catenin-TCF complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008013//beta-catenin binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016055//Wnt signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway"	HMG
ENSG00000152291	25.112	24.518	22.816	20.962	23.698	22.934	3040	2936	2080	1871	2420	2027	TGOLN2	trans-golgi network protein 2 [Source:HGNC Symbol;Acc:HGNC:15450]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0005515//protein binding	-	--
ENSG00000152292	0.206	0.232	0.23	0.162	0.103	0.044	4	6	4	2	3	1	SH2D6	SH2 domain containing 6 [Source:HGNC Symbol;Acc:HGNC:30439]	-	-	-	-	GO:0005737//cytoplasm	-	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction	--
ENSG00000152315	0.084	0.084	0.143	0.057	0.075	0.029	4	4	5	2	3	1	KCNK13	potassium two pore domain channel subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:6275]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000152332	16.674	14.386	14.106	13.866	14.643	14.749	2948	2543	1842	1816	2187	1897	UHMK1	U2AF homology motif kinase 1 [Source:HGNC Symbol;Acc:HGNC:19683]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0030424//axon;GO:0032839//dendrite cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0071598//neuronal ribonucleoprotein granule	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0043021//ribonucleoprotein complex binding;GO:0106310//protein serine kinase activity;GO:1990935//splicing factor binding	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031175//neuron projection development;GO:0045948//positive regulation of translational initiation;GO:0046777//protein autophosphorylation;GO:0046825//regulation of protein export from nucleus;GO:0051726//regulation of cell cycle	--
ENSG00000152348	2.745	2.429	2.175	1.332	3.127	2.685	128	116	59	62	107	88	ATG10	autophagy related 10 [Source:HGNC Symbol;Acc:HGNC:20315]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K17888;K17888	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019777//Atg12 transferase activity;GO:0019787//ubiquitin-like protein transferase activity	GO:0006497//protein lipidation;GO:0006914//autophagy;GO:0006983//ER overload response;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0031401//positive regulation of protein modification process;GO:0032446//protein modification by small protein conjugation	--
ENSG00000152359	2.869	1.889	1.455	1.833	1.529	2.398	83	84	47	48	45	55	POC5	POC5 centriolar protein [Source:HGNC Symbol;Acc:HGNC:26658]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007049//cell cycle	--
ENSG00000152377	29.109	29.296	24.728	25.301	25.819	25.605	2884	2901	1825	1850	2061	1848	SPOCK1	"SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0016528//sarcoplasm;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity	GO:0001558//regulation of cell growth;GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0010812//negative regulation of cell-substrate adhesion;GO:0010951//negative regulation of endopeptidase activity;GO:0010977//negative regulation of neuron projection development;GO:0021953//central nervous system neuron differentiation;GO:0022008//neurogenesis	--
ENSG00000152380	0.803	0.756	0.494	0.789	0.504	0.418	22	25	12	15	14	10	FAM151B	family with sequence similarity 151 member B [Source:HGNC Symbol;Acc:HGNC:33716]	-	-	-	-	GO:0005615//extracellular space	GO:0005515//protein binding	-	--
ENSG00000152382	7.361	7.094	7.443	5.807	6.888	8.125	320	310	239	187	253	257	TADA1	transcriptional adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30631]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0070461//SAGA-type complex	GO:0003713//transcription coactivator activity	"GO:0006282//regulation of DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000152402	0.242	0.262	0.233	0.341	0.174	0.419	81	61	34	33	30	39	GUCY1A2	guanylate cyclase 1 soluble subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4684]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Global and overview maps;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Immune system;Environmental adaptation;Digestive system;Cellular community - eukaryotes;Endocrine system;Nervous system	ko01100//Metabolic pathways;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04611//Platelet activation;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04540//Gap junction;ko04924//Renin secretion;ko04730//Long-term depression	K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004383//guanylate cyclase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0020037//heme binding	GO:0006182//cGMP biosynthetic process;GO:0007165//signal transduction;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010750//positive regulation of nitric oxide mediated signal transduction;GO:0035556//intracellular signal transduction	--
ENSG00000152404	2.603	2.587	2.127	1.284	1.777	1.948	173	175	102	64	101	95	CWF19L2	CWF19 like cell cycle control factor 2 [Source:HGNC Symbol;Acc:HGNC:26508]	-	-	-	-	GO:0071014//post-mRNA release spliceosomal complex	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000152409	4.866	3.333	3.947	2.977	3.105	3.278	918	632	550	416	495	450	JMY	"junction mediating and regulatory protein, p53 cofactor [Source:HGNC Symbol;Acc:HGNC:28916]"	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle	GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0071933//Arp2/3 complex binding	"GO:0006281//DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0009267//cellular response to starvation;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0070060//'de novo' actin filament nucleation;GO:0070358//actin polymerization-dependent cell motility;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator"	--
ENSG00000152413	4.054	3.127	3.867	4.077	4.231	4.452	450	378	301	270	340	298	HOMER1	homer scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:17512]	Environmental Information Processing;Organismal Systems	Signal transduction;Nervous system	ko04068//FoxO signaling pathway;ko04724//Glutamatergic synapse	K15010;K15010	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043034//costamere;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0044309//neuron spine;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099524//postsynaptic cytosol	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0035256//G protein-coupled glutamate receptor binding;GO:0035591//signaling adaptor activity;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0060090//molecular adaptor activity;GO:0097110//scaffold protein binding;GO:0099186//structural constituent of postsynapse	"GO:0003009//skeletal muscle contraction;GO:0007206//phospholipase C-activating G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007623//circadian rhythm;GO:0009967//positive regulation of signal transduction;GO:0035094//response to nicotine;GO:0035418//protein localization to synapse;GO:0042220//response to cocaine;GO:0048148//behavioral response to cocaine;GO:0048741//skeletal muscle fiber development;GO:0048875//chemical homeostasis within a tissue;GO:0051262//protein tetramerization;GO:0051592//response to calcium ion;GO:0051928//positive regulation of calcium ion transport;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0090279//regulation of calcium ion import;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0099173//postsynapse organization;GO:1902950//regulation of dendritic spine maintenance;GO:2001256//regulation of store-operated calcium entry;GO:2001257//regulation of cation channel activity"	--
ENSG00000152422	2.817	2.567	1.56	1.259	1.541	1.122	93	85	38	31	43	27	XRCC4	X-ray repair cross complementing 4 [Source:HGNC Symbol;Acc:HGNC:12831]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K10886	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0032807//DNA ligase IV complex;GO:0035861//site of double-strand break;GO:0070419//nonhomologous end joining complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0070975//FHA domain binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010165//response to X-ray;GO:0033152//immunoglobulin V(D)J recombination;GO:0051103//DNA ligation involved in DNA repair;GO:0051351//positive regulation of ligase activity;GO:1990166//protein localization to site of double-strand break	--
ENSG00000152430	0	0.046	0	0	0	0	0	3	0	0	0	0	BOLL	"boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273]"	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation;GO:0051321//meiotic cell cycle;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000152433	1.325	1.321	0.857	0.843	0.725	1.195	55	62	36.17	29	35	43	ZNF547	zinc finger protein 547 [Source:HGNC Symbol;Acc:HGNC:26432]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000152439	2.653	2.921	2.708	2.162	2.42	4.182	116.4	127.04	83.83	65.09	88.43	77.4	ZNF773	zinc finger protein 773 [Source:HGNC Symbol;Acc:HGNC:30487]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000152443	6.634	6.601	8.464	5.313	4.863	7.713	527	458	313	291	337	347	ZNF776	zinc finger protein 776 [Source:HGNC Symbol;Acc:HGNC:26765]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000152454	1.974	1.769	1.39	1.18	1.474	1.137	89	77	47	40	56	37	ZNF256	zinc finger protein 256 [Source:HGNC Symbol;Acc:HGNC:13049]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000152455	3.728	5.029	5.173	2.929	2.723	3.424	179	162	124	118	110	124	SUV39H2	SUV39H2 histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:17287]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11419;K11419	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031981//nuclear lumen"	GO:0000976//transcription cis-regulatory region binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:1904047//S-adenosyl-L-methionine binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006338//chromatin remodeling;GO:0007049//cell cycle;GO:0030154//cell differentiation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0036123//histone H3-K9 dimethylation;GO:0036124//histone H3-K9 trimethylation;GO:0042754//negative regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0071456//cellular response to hypoxia"	--
ENSG00000152457	1.597	1.511	1.506	1.253	1.298	1.104	143	126	87	60	94	85	DCLRE1C	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642]	Human Diseases;Genetic Information Processing	Immune disease;Replication and repair	ko05340//Primary immunodeficiency;ko03450//Non-homologous end-joining	K10887;K10887	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0070419//nonhomologous end joining complex	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003684//damaged DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0035312//5'-3' exodeoxyribonuclease activity	GO:0000723//telomere maintenance;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0030183//B cell differentiation;GO:0031848//protection from non-homologous end joining at telomere;GO:0033151//V(D)J recombination;GO:0036297//interstrand cross-link repair;GO:0051276//chromosome organization;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000152463	0	0.027	0.08	0	0	0	0	1	2	0	0	0	OLAH	oleoyl-ACP hydrolase [Source:HGNC Symbol;Acc:HGNC:25625]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00061//Fatty acid biosynthesis	K01071;K01071	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0016297//acyl-[acyl-carrier-protein] hydrolase activity;GO:0016787//hydrolase activity;GO:0047381//dodecanoyl-[acyl-carrier-protein] hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0008610//lipid biosynthetic process;GO:0009058//biosynthetic process;GO:0051792//medium-chain fatty acid biosynthetic process	--
ENSG00000152464	5.316	5.473	7.381	5.001	4.79	7.579	134	135	136	103	105	140	RPP38	ribonuclease P/MRP subunit p38 [Source:HGNC Symbol;Acc:HGNC:30329]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14523	GO:0000172//ribonuclease MRP complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000152465	6.847	6.787	6.76	5.965	7.091	6.328	468	443	330	283	405	299	NMT2	N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0043657//host cell	GO:0004379//glycylpeptide N-tetradecanoyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006499//N-terminal protein myristoylation;GO:0018008//N-terminal peptidyl-glycine N-myristoylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0075733//intracellular transport of virus	--
ENSG00000152467	0.438	0.378	0.562	0.801	0.351	0.815	8	7	7	10	5	10	ZSCAN1	zinc finger and SCAN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23712]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000152475	1.651	1.316	1.956	1.852	1.528	2.072	68	55	60	58	54	63	ZNF837	zinc finger protein 837 [Source:HGNC Symbol;Acc:HGNC:25164]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000152484	6.95	7.259	5.859	5.119	5.911	5.557	636	498	396	347	457	370	USP12	ubiquitin specific peptidase 12 [Source:HGNC Symbol;Acc:HGNC:20485]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0101005//deubiquitinase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000152492	21.405	19.126	17.644	14.737	14.789	15.997	1664	1434	1020	804	998	893	CCDC50	coiled-coil domain containing 50 [Source:HGNC Symbol;Acc:HGNC:18111]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0007605//sensory perception of sound	--
ENSG00000152495	0.559	0.459	0.298	1.064	0.161	0.385	78	61	38	40	16	16	CAMK4	calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Substance dependence;Endocrine system;Signal transduction;Development and regeneration;Nervous system;Nervous system;Endocrine system;Aging;Cancer: specific types;Substance dependence;Nervous system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04725//Cholinergic synapse;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko05214//Glioma;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869;K05869	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007616//long-term memory;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0033081//regulation of T cell differentiation in thymus;GO:0035556//intracellular signal transduction;GO:0043011//myeloid dendritic cell differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation"	--
ENSG00000152503	16.769	13.584	12.75	13.879	12.839	14.976	827	668	496	474	593	643	TRIM36	tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031410//cytoplasmic vesicle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding	GO:0000281//mitotic cytokinesis;GO:0007051//spindle organization;GO:0007340//acrosome reaction;GO:0016567//protein ubiquitination;GO:0051726//regulation of cell cycle;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000152518	59.856	57.394	55.944	51.833	53.743	51.727	4585	4419	3165	2941	3478	2883	ZFP36L2	ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K18753	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0046872//metal ion binding	"GO:0000165//MAPK cascade;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006402//mRNA catabolic process;GO:0009611//response to wounding;GO:0030097//hemopoiesis;GO:0033077//T cell differentiation in thymus;GO:0035019//somatic stem cell population maintenance;GO:0043488//regulation of mRNA stability;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045577//regulation of B cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0048103//somatic stem cell division;GO:0060216//definitive hemopoiesis;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0070371//ERK1 and ERK2 cascade;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:2000737//negative regulation of stem cell differentiation"	zf-CCCH
ENSG00000152520	4.522	3.489	3.801	2.848	3.619	3.962	499	375	307	239	339	314	PAN3	poly(A) specific ribonuclease subunit PAN3 [Source:HGNC Symbol;Acc:HGNC:29991]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12572	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031251//PAN complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008143//poly(A) binding;GO:0046872//metal ion binding	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000152527	2.231	1.648	2.035	1.601	1.992	2.179	294	221	218	172	212	230	PLEKHH2	"pleckstrin homology, MyTH4 and FERM domain containing H2 [Source:HGNC Symbol;Acc:HGNC:30506]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030027//lamellipodium;GO:0030864//cortical actin cytoskeleton;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding	GO:0030835//negative regulation of actin filament depolymerization	--
ENSG00000152556	55.702	56.461	63.193	59.701	49.948	53.157	2083	2285	1796	1765	1920	1631	PFKM	"phosphofructokinase, muscle [Source:HGNC Symbol;Acc:HGNC:8877]"	Metabolism;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Metabolism;Organismal Systems;Genetic Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	"Global and overview maps;Endocrine system;Signal transduction;Signal transduction;Global and overview maps;Endocrine system;Folding, sorting and degradation;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00030//Pentose phosphate pathway	K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850;K00850	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005945//6-phosphofructokinase complex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0097228//sperm principal piece	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003872//6-phosphofructokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008443//phosphofructokinase activity;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048029//monosaccharide binding;GO:0070061//fructose binding;GO:0070095//fructose-6-phosphate binding	"GO:0005980//glycogen catabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0042593//glucose homeostasis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046716//muscle cell cellular homeostasis;GO:0046835//carbohydrate phosphorylation;GO:0061615//glycolytic process through fructose-6-phosphate;GO:0061621//canonical glycolysis;GO:0093001//glycolysis from storage polysaccharide through glucose-1-phosphate"	--
ENSG00000152558	78.869	69.875	62.666	61.655	64.442	74.637	5311	4472	3172	2922	3503	3223	TMEM123	transmembrane protein 123 [Source:HGNC Symbol;Acc:HGNC:30138]	-	-	-	-	GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0070267//oncosis	--
ENSG00000152578	1.262	1.254	1.001	1.311	1.189	1.102	59	63	59	75	64	52	GRIA4	glutamate ionotropic receptor AMPA type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4574]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko04024//cAMP signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko05033//Nicotine addiction	K05200;K05200;K05200;K05200;K05200;K05200;K05200;K05200;K05200;K05200	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0110165//cellular anatomical entity;GO:1903561//extracellular vesicle	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004971//AMPA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0038023//signaling receptor activity	GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0035235//ionotropic glutamate receptor signaling pathway	--
ENSG00000152580	2.043	1.669	0.877	0.509	0.808	0.673	286	297.86	114.99	67	121.21	87	IGSF10	immunoglobulin superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:26384]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0001503//ossification;GO:0030154//cell differentiation;GO:2001222//regulation of neuron migration	--
ENSG00000152582	2.369	1.641	1.236	1.442	1.245	1.27	198	139	83	74	96	75	SPEF2	sperm flagellar 2 [Source:HGNC Symbol;Acc:HGNC:26293]	-	-	-	-	GO:0002177//manchette;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece;GO:0110165//cellular anatomical entity	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation;GO:0048705//skeletal system morphogenesis;GO:0048854//brain morphogenesis;GO:0060541//respiratory system development	--
ENSG00000152583	1.586	0.973	0.47	0.384	0.388	0.155	61	48	20	6	18	7	SPARCL1	SPARC like 1 [Source:HGNC Symbol;Acc:HGNC:11220]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix;GO:0098978//glutamatergic synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0007165//signal transduction;GO:0048856//anatomical structure development;GO:0099560//synaptic membrane adhesion	--
ENSG00000152591	0	0	0	0	0	0	0	0	0	0	0	0	DSPP	dentin sialophosphoprotein [Source:HGNC Symbol;Acc:HGNC:3054]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K23573	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005518//collagen binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0007275//multicellular organism development;GO:0031214//biomineral tissue development;GO:0071895//odontoblast differentiation;GO:0097187//dentinogenesis;GO:1901329//regulation of odontoblast differentiation	--
ENSG00000152592	0	0	0	0	0	0	0	0	0	0	0	0	DMP1	dentin matrix acidic phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:2932]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K23328	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding	GO:0001503//ossification;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0031214//biomineral tissue development;GO:0070173//regulation of enamel mineralization	--
ENSG00000152595	0	0	0	0	0	0	0	0	0	0	0	0	MEPE	matrix extracellular phosphoglycoprotein [Source:HGNC Symbol;Acc:HGNC:13361]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:1990430//extracellular matrix protein binding	GO:0001501//skeletal system development;GO:0031214//biomineral tissue development	--
ENSG00000152601	9.316	7.457	5.841	4.93	6.059	7.111	1063	803	485	391	541	558	MBNL1	muscleblind like splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:6923]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0001069//regulatory region RNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0030326//embryonic limb morphogenesis;GO:0043484//regulation of RNA splicing;GO:0045445//myoblast differentiation"	--
ENSG00000152611	0.258	0.958	0.483	0.202	0.227	0.404	4	15	6	3	4	4	CAPSL	calcyphosine like [Source:HGNC Symbol;Acc:HGNC:28375]	-	-	-	-	GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000152620	9.466	7.415	7.26	5.512	6.11	6.508	509.9	421.98	301.97	230	298.98	275.96	NADK2	"NAD kinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26404]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00858;K00858	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	GO:0006741//NADP biosynthetic process;GO:0016310//phosphorylation;GO:0019674//NAD metabolic process	--
ENSG00000152642	7.23	6.963	7.309	6.316	6.506	7.353	574	573	427	383	450	438	GPD1L	glycerol-3-phosphate dehydrogenase 1 like [Source:HGNC Symbol;Acc:HGNC:28956]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K00006	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0017080//sodium channel regulator activity;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0051287//NAD binding"	GO:0002027//regulation of heart rate;GO:0005975//carbohydrate metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006734//NADH metabolic process;GO:0010765//positive regulation of sodium ion transport;GO:0019674//NAD metabolic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0046168//glycerol-3-phosphate catabolic process;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0090038//negative regulation of protein kinase C signaling;GO:2000010//positive regulation of protein localization to cell surface;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000152661	313.264	292.546	311.395	342.37	318.03	397.909	19984	18802	14707	16197	17182	18492	GJA1	gap junction protein alpha 1 [Source:HGNC Symbol;Acc:HGNC:4274]	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Cardiovascular disease	ko04540//Gap junction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K07372;K07372	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005916//fascia adherens;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0005925//focal adhesion;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030660//Golgi-associated vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber;GO:0044291//cell-cell contact zone;GO:0045121//membrane raft;GO:0070160//tight junction	GO:0005102//signaling receptor binding;GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0015075//ion transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0015631//tubulin binding;GO:0022857//transmembrane transporter activity;GO:0034634//glutathione transmembrane transporter activity;GO:0048487//beta-tubulin binding;GO:0055077//gap junction hemi-channel activity;GO:0086075//gap junction channel activity involved in cardiac conduction electrical coupling;GO:0097110//scaffold protein binding;GO:1903763//gap junction channel activity involved in cell communication by electrical coupling;GO:1990782//protein tyrosine kinase binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001764//neuron migration;GO:0001947//heart looping;GO:0002070//epithelial cell maturation;GO:0002088//lens development in camera-type eye;GO:0003161//cardiac conduction system development;GO:0003294//atrial ventricular junction remodeling;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0007507//heart development;GO:0007512//adult heart development;GO:0008016//regulation of heart contraction;GO:0008584//male gonad development;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010643//cell communication by chemical coupling;GO:0010644//cell communication by electrical coupling;GO:0014047//glutamate secretion;GO:0016264//gap junction assembly;GO:0030308//negative regulation of cell growth;GO:0030500//regulation of bone mineralization;GO:0032277//negative regulation of gonadotropin secretion;GO:0034220//ion transmembrane transport;GO:0034613//cellular protein localization;GO:0034775//glutathione transmembrane transport;GO:0035050//embryonic heart tube development;GO:0035633//maintenance of blood-brain barrier;GO:0042098//T cell proliferation;GO:0042110//T cell activation;GO:0042733//embryonic digit morphogenesis;GO:0042908//xenobiotic transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043403//skeletal muscle tissue regeneration;GO:0045216//cell-cell junction organization;GO:0045844//positive regulation of striated muscle tissue development;GO:0046849//bone remodeling;GO:0046850//regulation of bone remodeling;GO:0048514//blood vessel morphogenesis;GO:0060156//milk ejection reflex;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060348//bone development;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0061337//cardiac conduction;GO:0071467//cellular response to pH;GO:0086014//atrial cardiac muscle cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0140115//export across plasma membrane;GO:1901164//negative regulation of trophoblast cell migration;GO:1904646//cellular response to amyloid-beta;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905332//positive regulation of morphogenesis of an epithelium;GO:1905772//positive regulation of mesodermal cell differentiation;GO:2000648//positive regulation of stem cell proliferation	--
ENSG00000152669	53.094	55.28	39.776	25.271	29.685	30.967	1633	1723	923	589	781	710	CCNO	cyclin O [Source:HGNC Symbol;Acc:HGNC:18576]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0097124//cyclin A2-CDK2 complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0009410//response to xenobiotic stimulus;GO:0030030//cell projection organization;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0060271//cilium assembly;GO:1903251//multi-ciliated epithelial cell differentiation	--
ENSG00000152670	0	0	0.033	0.04	0	0	0	0	1	1	0	0	DDX4	DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043186//P granule;GO:0048471//perinuclear region of cytoplasm;GO:0071546//pi-body;GO:0071547//piP-body	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007276//gamete generation;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle;GO:1990511//piRNA biosynthetic process	--
ENSG00000152672	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4F	C-type lectin domain family 4 member F [Source:HGNC Symbol;Acc:HGNC:25357]	-	-	-	-	GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding	GO:0006897//endocytosis	--
ENSG00000152683	9.429	7.88	8.446	7.791	7.491	8.94	879	781	570	529	608	618	SLC30A6	solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0030070//insulin processing;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000152684	5.472	5.259	5.227	4.718	4.638	5.528	496.15	479.24	350.02	316.83	355.28	364.65	PELO	pelota mRNA surveillance and ribosome rescue factor [Source:HGNC Symbol;Acc:HGNC:8829]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K06965	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0001833//inner cell mass cell proliferation;GO:0006417//regulation of translation;GO:0007049//cell cycle;GO:0007492//endoderm development;GO:0019827//stem cell population maintenance;GO:0030513//positive regulation of BMP signaling pathway;GO:0032790//ribosome disassembly;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0060231//mesenchymal to epithelial transition;GO:0070481//nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0070651//nonfunctional rRNA decay;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0071025//RNA surveillance;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000152689	13.433	11.086	10.632	13.135	13.441	12.364	877	783	618	653	701	667	RASGRP3	RAS guanyl releasing protein 3 [Source:HGNC Symbol;Acc:HGNC:14545]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Immune system	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04662//B cell receptor signaling pathway	K12362;K12362;K12362;K12362;K12362	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019992//diacylglycerol binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0000165//MAPK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity	--
ENSG00000152700	21.454	22.172	19.695	15.425	15.499	21.177	1107.26	1058.53	800.94	644.8	727.08	741.06	SAR1B	secretion associated Ras related GTPase 1B [Source:HGNC Symbol;Acc:HGNC:10535]	Genetic Information Processing;Human Diseases	"Folding, sorting and degradation;Infectious disease: bacterial"	ko04141//Protein processing in endoplasmic reticulum;ko05134//Legionellosis	K07953;K07953	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0032580//Golgi cisterna membrane;GO:0070971//endoplasmic reticulum exit site	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0003400//regulation of COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016050//vesicle organization;GO:0016192//vesicle-mediated transport;GO:0032368//regulation of lipid transport;GO:0042953//lipoprotein transport;GO:0055088//lipid homeostasis;GO:0061024//membrane organization;GO:0070863//positive regulation of protein exit from endoplasmic reticulum	--
ENSG00000152705	0.071	0.301	0	0.096	0.168	0.098	2	8.5	0	2	4	2	CATSPER3	cation channel sperm associated 3 [Source:HGNC Symbol;Acc:HGNC:20819]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0034765//regulation of ion transmembrane transport;GO:0048240//sperm capacitation;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000152749	13.779	10.528	12.594	8.125	8.614	9.159	2539	1950	1714	1109	1341	1228	GPR180	G protein-coupled receptor 180 [Source:HGNC Symbol;Acc:HGNC:28899]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007186//G protein-coupled receptor signaling pathway;GO:0019236//response to pheromone	--
ENSG00000152760	0.277	0.18	0.148	0.086	0.05	0.088	13	7	4	3	2	3	DYNLT5	dynein light chain Tctex-type family member 5 [Source:HGNC Symbol;Acc:HGNC:26882]	-	-	-	-	GO:0005737//cytoplasm;GO:0005868//cytoplasmic dynein complex	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000152763	2.919	3.108	1.754	2.122	1.102	1.681	205	187	89	69	74	59	DNAI4	dynein axonemal intermediate chain 4 [Source:HGNC Symbol;Acc:HGNC:26252]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0070286//axonemal dynein complex assembly	--
ENSG00000152766	0	0	0	0	0	0	0	0	0	0	0	0	ANKRD22	ankyrin repeat domain 22 [Source:HGNC Symbol;Acc:HGNC:28321]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000152767	18.067	17.31	18.038	12.55	14.801	11.555	2361.15	2171.53	1689.02	1276.26	1546	1176.84	FARP1	"FERM, ARH/RhoGEF and pleckstrin domain protein 1 [Source:HGNC Symbol;Acc:HGNC:3591]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098890//extrinsic component of postsynaptic membrane;GO:0098978//glutamatergic synapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0031267//small GTPase binding	GO:0007416//synapse assembly;GO:0048813//dendrite morphogenesis;GO:0050790//regulation of catalytic activity;GO:0098942//retrograde trans-synaptic signaling by trans-synaptic protein complex;GO:0098974//postsynaptic actin cytoskeleton organization;GO:1905606//regulation of presynapse assembly	--
ENSG00000152778	5.885	4.378	4.65	4.942	5.498	5.368	375	308	244	227	293	253	IFIT5	interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008385//IkappaB kinase complex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0045177//apical part of cell	GO:0000049//tRNA binding;GO:0000339//RNA cap binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding	GO:0002376//immune system process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000152779	3.262	3.308	3.071	2.503	3.04	2.633	315	321	219	179	248	185	SLC16A12	solute carrier family 16 member 12 [Source:HGNC Symbol;Acc:HGNC:23094]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005308//creatine transmembrane transporter activity;GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0015881//creatine transmembrane transport;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000152782	10.077	11.658	12.391	11.572	11.553	12.011	630	720	575	535	622	543	PANK1	pantothenate kinase 1 [Source:HGNC Symbol;Acc:HGNC:8598]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00770//Pantothenate and CoA biosynthesis	K09680;K09680	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0004594//pantothenate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:1905502//acetyl-CoA binding	GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000152784	0	0.031	0	0	0.046	0	0	2	0	0	3	0	PRDM8	PR/SET domain 8 [Source:HGNC Symbol;Acc:HGNC:13993]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0014003//oligodendrocyte development;GO:0032259//methylation"	zf-C2H2
ENSG00000152785	0.032	0	0	0.021	0	0	4	0	0	2	0	0	BMP3	bone morphogenetic protein 3 [Source:HGNC Symbol;Acc:HGNC:1070]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05496	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070700//BMP receptor binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0007267//cell-cell signaling;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030154//cell differentiation;GO:0051216//cartilage development;GO:0060395//SMAD protein signal transduction	--
ENSG00000152795	92.283	86.063	86.741	79.363	77.574	91.896	3313	3057	2285	2038	2316	2403	HNRNPDL	heterogeneous nuclear ribonucleoprotein D like [Source:HGNC Symbol;Acc:HGNC:5037]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0034046//poly(G) binding	GO:0006396//RNA processing;GO:0010468//regulation of gene expression	--
ENSG00000152804	0.06	0.245	0.081	0.081	0.099	0.077	2	5	1	2	3	2	HHEX	hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901]	Human Diseases;Human Diseases	Cancer: overview;Endocrine and metabolic disease	ko05202//Transcriptional misregulation in cancer;ko04950//Maturity onset diabetes of the young	K08024;K08024	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032993//protein-DNA complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0008301//DNA binding, bending;GO:0017025//TBP-class protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006406//mRNA export from nucleus;GO:0009952//anterior/posterior pattern specification;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0016055//Wnt signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0030154//cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030183//B cell differentiation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0034504//protein localization to nucleus;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070663//regulation of leukocyte proliferation;GO:0071103//DNA conformation change;GO:0090263//positive regulation of canonical Wnt signaling pathway"	Homeobox
ENSG00000152818	22.448	15.185	11.767	8.863	10.807	8.989	3642	2206	1530	955	1365	1080	UTRN	utrophin [Source:HGNC Symbol;Acc:HGNC:12635]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016020//membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030864//cortical actin cytoskeleton;GO:0031527//filopodium membrane;GO:0031594//neuromuscular junction;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0070938//contractile ring	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017166//vinculin binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0001954//positive regulation of cell-matrix adhesion;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0030036//actin cytoskeleton organization;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000152822	0.328	0.365	0.271	0.125	0.126	0.098	46	36	28	13	13	10	GRM1	glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Signal transduction;Nervous system;Neurodegenerative disease;Endocrine system;Signal transduction;Nervous system;Cellular community - eukaryotes;Sensory system;Nervous system;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04072//Phospholipase D signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04915//Estrogen signaling pathway;ko04068//FoxO signaling pathway;ko04724//Glutamatergic synapse;ko04540//Gap junction;ko04742//Taste transduction;ko04720//Long-term potentiation;ko04730//Long-term depression	K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603;K04603	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0038037//G protein-coupled receptor dimeric complex;GO:0038038//G protein-coupled receptor homodimeric complex;GO:0043005//neuron projection;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0098872//G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:0099530//G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:0099583//neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007626//locomotory behavior;GO:0019233//sensory perception of pain;GO:0043410//positive regulation of MAPK cascade;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051930//regulation of sensory perception of pain;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0071257//cellular response to electrical stimulus;GO:0098712//L-glutamate import across plasma membrane;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration"	--
ENSG00000152894	33.766	29.904	27.429	27.531	30.29	34.509	3685	3343	2324	2314	2852	2696	PTPRK	protein tyrosine phosphatase receptor type K [Source:HGNC Symbol;Acc:HGNC:9674]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031256//leading edge membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0045295//gamma-catenin binding	"GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016311//dephosphorylation;GO:0016477//cell migration;GO:0030336//negative regulation of cell migration;GO:0034394//protein localization to cell surface;GO:0034614//cellular response to reactive oxygen species;GO:0034644//cellular response to UV;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048041//focal adhesion assembly"	--
ENSG00000152904	14.398	14.358	15.492	12.514	12.156	13.24	593	574.32	450	388	433	387	GGPS1	geranylgeranyl diphosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:4249]	Metabolism;Metabolism	Global and overview maps;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko00900//Terpenoid backbone biosynthesis	K00804;K00804	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004161//dimethylallyltranstransferase activity;GO:0004311//farnesyltranstransferase activity;GO:0004337//geranyltranstransferase activity;GO:0004659//prenyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006720//isoprenoid metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0033384//geranyl diphosphate biosynthetic process;GO:0033386//geranylgeranyl diphosphate biosynthetic process;GO:0045337//farnesyl diphosphate biosynthetic process	--
ENSG00000152910	0	0	0	0	0	0	0	0	0	0	0	0	CNTNAP4	contactin associated protein family member 4 [Source:HGNC Symbol;Acc:HGNC:18747]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0032228//regulation of synaptic transmission, GABAergic;GO:2000821//regulation of grooming behavior"	--
ENSG00000152926	3.187	1.439	1.478	2.203	2.931	2.028	375.7	187.04	127.26	197.16	289.72	175.07	ZNF117	zinc finger protein 117 [Source:HGNC Symbol;Acc:HGNC:12897]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000152932	0	0	0	0	0	0	0	0	0	0	0	0	RAB3C	"RAB3C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30269]"	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding;GO:0031489//myosin V binding	GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0019882//antigen processing and presentation;GO:0072659//protein localization to plasma membrane	--
ENSG00000152936	0.225	0	0	0.296	0.151	0.582	7	0	0	6	2	6	LMNTD1	lamin tail domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26683]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005882//intermediate filament	-	GO:0008283//cell population proliferation	--
ENSG00000152939	3.748	3.761	3.75	2.853	3.756	3.812	254	282	203	156	233	210	MARVELD2	MARVEL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26401]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K17291	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0033010//paranodal junction;GO:0043220//Schmidt-Lanterman incisure;GO:0061689//tricellular tight junction;GO:0070160//tight junction	GO:0005515//protein binding	GO:0007605//sensory perception of sound;GO:0045216//cell-cell junction organization;GO:0061028//establishment of endothelial barrier;GO:0070830//bicellular tight junction assembly	--
ENSG00000152942	12.16	9.806	11.864	8.782	9.474	12.934	715	594	410	391.14	426	464	RAD17	RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031389//Rad17 RFC-like complex"	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0000076//DNA replication checkpoint signaling;GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008156//negative regulation of DNA replication;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0042325//regulation of phosphorylation	--
ENSG00000152944	13.226	10.19	10.419	8.706	8.659	10.973	685	567	426	357	405	442	MED21	mediator complex subunit 21 [Source:HGNC Symbol;Acc:HGNC:11473]	-	-	-	-	GO:0005634//nucleus;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	GO:0001824//blastocyst development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000152952	73.061	57.84	44.616	27.896	36.045	37.227	5505	4370	2319	1578	2082	1989	PLOD2	"procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:9082]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K13645;K13645	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0070062//extracellular exosome	"GO:0005506//iron ion binding;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001666//response to hypoxia;GO:0006464//cellular protein modification process;GO:0017185//peptidyl-lysine hydroxylation;GO:0046947//hydroxylysine biosynthetic process	--
ENSG00000152953	1.29	1.447	2.115	1.565	1.557	1.952	86	105	114	85	92	100	STK32B	serine/threonine kinase 32B [Source:HGNC Symbol;Acc:HGNC:14217]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000152954	0	0	0	0	0	0.028	0	0	0	0	0	1	NRSN1	neurensin 1 [Source:HGNC Symbol;Acc:HGNC:17881]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0005515//protein binding	GO:0007399//nervous system development	--
ENSG00000152969	0.279	0.357	0	0.03	0	0	11	17	0	0.84	0	0	JAKMIP1	janus kinase and microtubule interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:26460]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019900//kinase binding;GO:0050811//GABA receptor binding	GO:0015031//protein transport;GO:0050890//cognition	--
ENSG00000152977	5.021	4.148	5.774	6.357	7.788	4.205	181	188	152	165	233	133	ZIC1	Zic family member 1 [Source:HGNC Symbol;Acc:HGNC:12872]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007628//adult walking behavior;GO:0008589//regulation of smoothened signaling pathway;GO:0021510//spinal cord development;GO:0030154//cell differentiation;GO:0042307//positive regulation of protein import into nucleus;GO:0042472//inner ear morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000152990	24.903	23.862	24.043	20.279	21.623	20.538	2318	2260	1680	1369	1669	1402	ADGRA3	adhesion G protein-coupled receptor A3 [Source:HGNC Symbol;Acc:HGNC:13839]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000153002	0	0	0	0	0.039	0	0	0	0	0	1	0	CPB1	carboxypeptidase B1 [Source:HGNC Symbol;Acc:HGNC:2299]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01291;K01291	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000153006	3.098	2.713	2.259	1.542	1.693	1.936	442	389	238	163	204	201	SREK1IP1	SREK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:26716]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000153012	0.022	0.03	0	0.06	0.07	0.071	3	4	0	6	8	7	LGI2	leucine rich repeat LGI family member 2 [Source:HGNC Symbol;Acc:HGNC:18710]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:1904862//inhibitory synapse assembly	--
ENSG00000153015	6.802	6.447	6.215	3.77	3.994	5.664	282	258	196	113	140	172	CWC27	CWC27 spliceosome associated cyclophilin [Source:HGNC Symbol;Acc:HGNC:10664]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding"	--
ENSG00000153029	5.991	5.331	6.69	3.38	4.239	4.94	416	395	287	160	218	209	MR1	"major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:HGNC:4975]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0042612//MHC class I protein complex	GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0032393//MHC class I receptor activity;GO:0042608//T cell receptor binding	GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002854//positive regulation of T cell mediated cytotoxicity directed against tumor cell target;GO:0006955//immune response;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0033077//T cell differentiation in thymus;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000153037	14.775	15.809	16.703	11.904	10.997	15.872	405.75	403.2	333.68	239.68	284.85	315.23	SRP19	signal recognition particle 19 [Source:HGNC Symbol;Acc:HGNC:11300]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03105	"GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0048500//signal recognition particle"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008312//7S RNA binding;GO:0043022//ribosome binding	"GO:0006613//cotranslational protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006617//SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"	--
ENSG00000153044	1.424	1.083	1.489	0.865	0.969	0.881	40	26	28	18	23	18	CENPH	centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol"	GO:0005515//protein binding;GO:0043515//kinetochore binding	GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0051382//kinetochore assembly;GO:0051383//kinetochore organization	--
ENSG00000153046	7.934	7.21	6.89	6.694	6.416	7.476	508	480	339	315	347	382	CDYL	chromodomain Y like [Source:HGNC Symbol;Acc:HGNC:1811]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0030674//protein-macromolecule adaptor activity;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:0120092//crotonyl-CoA hydratase activity	"GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060816//random inactivation of X chromosome;GO:0120094//negative regulation of peptidyl-lysine crotonylation"	--
ENSG00000153048	36.565	36.957	38.927	29.446	26.231	39.952	939.97	944	798.99	616	636.97	729	CARHSP1	calcium regulated heat stable protein 1 [Source:HGNC Symbol;Acc:HGNC:17150]	-	-	-	-	GO:0000177//cytoplasmic exosome (RNase complex);GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043186//P granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0019902//phosphatase binding	GO:0035556//intracellular signal transduction;GO:0043488//regulation of mRNA stability	CSD
ENSG00000153060	0.21	0.21	0.286	0	0.143	0.312	4	7	4	0	4	6	TEKT5	tektin 5 [Source:HGNC Symbol;Acc:HGNC:26554]	-	-	-	-	GO:0005634//nucleus;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility	--
ENSG00000153064	0.415	0.171	0.104	0.191	0.162	0.344	25	11	5	8	6	16	BANK1	B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233]	-	-	-	-	GO:0048471//perinuclear region of cytoplasm	GO:0002020//protease binding;GO:0003953//NAD+ nucleosidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0035591//signaling adaptor activity;GO:0043274//phospholipase binding;GO:1990782//protein tyrosine kinase binding	GO:0007165//signal transduction;GO:0009617//response to bacterium;GO:0032715//negative regulation of interleukin-6 production;GO:0042113//B cell activation;GO:0043410//positive regulation of MAPK cascade;GO:0045947//negative regulation of translational initiation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050853//B cell receptor signaling pathway;GO:0050869//negative regulation of B cell activation;GO:0051898//negative regulation of protein kinase B signaling	--
ENSG00000153066	38.555	38.204	35.225	27.564	29.912	26.892	2259	2356	1592	1250	1509	1149	TXNDC11	thioredoxin domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28030]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000153071	21.281	21.452	23.881	25.636	24.847	24.512	1800	1817	1470	1579	1735	1562	DAB2	DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12475	GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0035615//clathrin adaptor activity;GO:0038024//cargo receptor activity;GO:0046332//SMAD binding;GO:0050750//low-density lipoprotein particle receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001934//positive regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010977//negative regulation of neuron projection development;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035026//leading edge cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045807//positive regulation of endocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048268//clathrin coat assembly;GO:0048545//response to steroid hormone;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902074//response to salt;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:2000370//positive regulation of clathrin-dependent endocytosis;GO:2000643//positive regulation of early endosome to late endosome transport;GO:2000860//positive regulation of aldosterone secretion"	--
ENSG00000153086	0	0	0	0	0	0	0	0	0	0	0	0	ACMSD	aminocarboxymuconate semialdehyde decarboxylase [Source:HGNC Symbol;Acc:HGNC:19288]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K03392;K03392	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001760//aminocarboxymuconate-semialdehyde decarboxylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0046872//metal ion binding	GO:0006569//tryptophan catabolic process;GO:0019748//secondary metabolic process;GO:1904985//negative regulation of quinolinate biosynthetic process;GO:1905004//picolinic acid biosynthetic process;GO:1905012//regulation of 'de novo' NAD biosynthetic process from tryptophan	--
ENSG00000153093	0.553	0.491	0.388	0.68	0.713	0.475	56	50	29	51	61	35	ACOXL	acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621]	-	-	-	-	GO:0005575//cellular_component;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix	"GO:0003674//molecular_function;GO:0003997//acyl-CoA oxidase activity;GO:0005504//fatty acid binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0008150//biological_process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088//lipid homeostasis	--
ENSG00000153094	9.024	10.324	6.68	6.263	4.789	6.248	475	471	317	334	361	367	BCL2L11	BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05169//Epstein-Barr virus infection;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko04210//Apoptosis;ko04068//FoxO signaling pathway;ko05210//Colorectal cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04215//Apoptosis - multiple species	K16341;K16341;K16341;K16341;K16341;K16341;K16341;K16341;K16341;K16341	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005874//microtubule;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097136//Bcl-2 family protein complex;GO:0097140//BIM-BCL-xl complex;GO:0097141//BIM-BCL-2 complex	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding	GO:0001701//in utero embryonic development;GO:0001776//leukocyte homeostasis;GO:0001782//B cell homeostasis;GO:0001822//kidney development;GO:0002260//lymphocyte homeostasis;GO:0002262//myeloid cell homeostasis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007127//meiosis I;GO:0007160//cell-matrix adhesion;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008584//male gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009791//post-embryonic development;GO:0010942//positive regulation of cell death;GO:0030879//mammary gland development;GO:0031334//positive regulation of protein-containing complex assembly;GO:0034263//positive regulation of autophagy in response to ER overload;GO:0034976//response to endoplasmic reticulum stress;GO:0035148//tube formation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042981//regulation of apoptotic process;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043583//ear development;GO:0045787//positive regulation of cell cycle;GO:0046620//regulation of organ growth;GO:0048066//developmental pigmentation;GO:0048070//regulation of developmental pigmentation;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048563//post-embryonic animal organ morphogenesis;GO:0070242//thymocyte apoptotic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:1904646//cellular response to amyloid-beta;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000153107	10.629	10.015	10.645	7.957	9.389	10.276	1585	1578	1203	898	1258	1141	ANAPC1	anaphase promoting complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:19988]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03348;K03348;K03348;K03348;K03348	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000153113	35.341	32.286	24.646	16.809	24.503	22.026	2417.24	2135	1289	865.51	1274	1076	CAST	calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K04281	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane	GO:0003723//RNA binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0010859//calcium-dependent cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0045296//cadherin binding	GO:0010466//negative regulation of peptidase activity;GO:0097340//inhibition of cysteine-type endopeptidase activity;GO:1990709//presynaptic active zone organization;GO:2000675//negative regulation of type B pancreatic cell apoptotic process	--
ENSG00000153130	51.291	45.065	46.356	40.799	33.204	39.459	2106	1822	1311	1216	1185	1114	SCOC	short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	GO:0016239//positive regulation of macroautophagy;GO:0061635//regulation of protein complex stability	--
ENSG00000153132	61.71	61.292	37.207	14.856	18.635	17.387	3479	3456	1537	622	882	703	CLGN	calmegin [Source:HGNC Symbol;Acc:HGNC:2060]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0065003//protein-containing complex assembly	--
ENSG00000153140	8.694	6.684	10.364	8.625	8.094	8.487	181	153	176	132	138	131	CETN3	centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0032391//photoreceptor connecting cilium;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0044615//nuclear pore nuclear basket;GO:0070390//transcription export complex 2	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051301//cell division	--
ENSG00000153147	16.89	12.903	12.004	8.962	11.088	11.59	2692	2067	1413	1058	1493	1344	SMARCA5	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101]"	-	-	-	-	GO:0000793//condensed chromosome;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005730//nucleolus;GO:0008623//CHRAC;GO:0016589//NURF complex;GO:0016590//ACF complex;GO:0031010//ISWI-type complex;GO:0031213//RSF complex;GO:0043596//nuclear replication fork;GO:0090535//WICH complex;GO:0090536//NoRC complex;GO:0110016//B-WICH complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000183//rDNA heterochromatin assembly;GO:0006275//regulation of DNA replication;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016479//negative regulation of transcription by RNA polymerase I;GO:0016584//nucleosome positioning;GO:0031062//positive regulation of histone methylation;GO:0031065//positive regulation of histone deacetylation;GO:0031497//chromatin assembly;GO:0031507//heterochromatin assembly;GO:0035066//positive regulation of histone acetylation;GO:0042766//nucleosome mobilization;GO:0044030//regulation of DNA methylation;GO:0045740//positive regulation of DNA replication;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:1905213//negative regulation of mitotic chromosome condensation;GO:1990164//histone H2A phosphorylation;GO:1990830//cellular response to leukemia inhibitory factor;GO:2001020//regulation of response to DNA damage stimulus"	--
ENSG00000153157	0.22	0.148	0.08	0.134	0.211	0.459	12	9	3	6	9	11	SYCP2L	synaptonemal complex protein 2 like [Source:HGNC Symbol;Acc:HGNC:21537]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000779//condensed chromosome, centromeric region;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome"	-	GO:0060548//negative regulation of cell death;GO:0140013//meiotic nuclear division	--
ENSG00000153162	10.486	10.497	11.869	23.087	21.255	19.91	823	828.11	688	1342.25	1409.42	1137	BMP6	bone morphogenetic protein 6 [Source:HGNC Symbol;Acc:HGNC:1073]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Endocrine system	ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway;ko04913//Ovarian steroidogenesis	K16620;K16620;K16620;K16620	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031982//vesicle	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0046982//protein heterodimerization activity;GO:0070700//BMP receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001654//eye development;GO:0001822//kidney development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001958//endochondral ossification;GO:0003323//type B pancreatic cell development;GO:0006879//cellular iron ion homeostasis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0008284//positive regulation of cell population proliferation;GO:0010039//response to iron ion;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014823//response to activity;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030539//male genitalia development;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032026//response to magnesium ion;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:0032526//response to retinoic acid;GO:0043117//positive regulation of vascular permeability;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051216//cartilage development;GO:0051384//response to glucocorticoid;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0060586//multicellular organismal iron ion homeostasis;GO:0071260//cellular response to mechanical stimulus;GO:0071281//cellular response to iron ion;GO:0071773//cellular response to BMP stimulus;GO:1903392//negative regulation of adherens junction organization;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000860//positive regulation of aldosterone secretion	--
ENSG00000153165	0.087	0.111	0.144	0.063	0.096	0.052	13.06	12.72	13.12	6.29	12.17	5.65	RGPD3	RANBP2 like and GRIP domain containing 3 [Source:HGNC Symbol;Acc:HGNC:32416]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000153179	32.156	31.001	32.815	26.218	30.952	26.984	1889	1815	1487	1273	1499	1262	RASSF3	Ras association domain family member 3 [Source:HGNC Symbol;Acc:HGNC:14271]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0042981//regulation of apoptotic process	--
ENSG00000153187	130.422	124.172	129.579	108.376	114.775	112.217	8568.62	8193.45	6269.48	5235.59	6157.16	5279.07	HNRNPU	heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12888	"GO:0000228//nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0030496//midbody;GO:0032839//dendrite cytoplasm;GO:0032991//protein-containing complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070937//CRD-mediated mRNA stability complex;GO:0071013//catalytic step 2 spliceosome;GO:0072686//mitotic spindle;GO:0090575//RNA polymerase II transcription regulator complex;GO:0098577//inactive sex chromosome;GO:1990023//mitotic spindle midzone;GO:1990498//mitotic spindle microtubule;GO:1990904//ribonucleoprotein complex"	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0001097//TFIIH-class transcription factor complex binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008143//poly(A) binding;GO:0017069//snRNA binding;GO:0017130//poly(C) RNA binding;GO:0031490//chromatin DNA binding;GO:0034046//poly(G) binding;GO:0036002//pre-mRNA binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0070034//telomerase RNA binding;GO:0099122//RNA polymerase II C-terminal domain binding;GO:0106222//long noncoding RNA binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation;GO:0006325//chromatin organization;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008380//RNA splicing;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0016071//mRNA metabolic process;GO:0030154//cell differentiation;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032922//circadian regulation of gene expression;GO:0033673//negative regulation of kinase activity;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048255//mRNA stabilization;GO:0048511//rhythmic process;GO:0051301//cell division;GO:0051457//maintenance of protein location in nucleus;GO:0055013//cardiac muscle cell development;GO:0070934//CRD-mediated mRNA stabilization;GO:0071385//cellular response to glucocorticoid stimulus;GO:0090336//positive regulation of brown fat cell differentiation;GO:0098963//dendritic transport of messenger ribonucleoprotein complex;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901673//regulation of mitotic spindle assembly;GO:1902275//regulation of chromatin organization;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1902889//protein localization to spindle microtubule;GO:1990280//RNA localization to chromatin;GO:1990830//cellular response to leukemia inhibitory factor;GO:1990845//adaptive thermogenesis;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:2000648//positive regulation of stem cell proliferation;GO:2000737//negative regulation of stem cell differentiation;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000153201	11.248	6.368	6.411	4.235	5.363	5.952	2731.44	1554.39	1149.8	761.81	1100.4	1051.65	RANBP2	RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K12172;K12172	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005642//annulate lamellae;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0042405//nuclear inclusion body;GO:0043231//intracellular membrane-bounded organelle;GO:0044614//nuclear pore cytoplasmic filaments;GO:0044615//nuclear pore nuclear basket;GO:0106068//SUMO ligase complex	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0061665//SUMO ligase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006111//regulation of gluconeogenesis;GO:0006457//protein folding;GO:0006607//NLS-bearing protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0016925//protein sumoylation;GO:0033133//positive regulation of glucokinase activity;GO:0046907//intracellular transport;GO:0051028//mRNA transport;GO:0051168//nuclear export;GO:0051642//centrosome localization	--
ENSG00000153207	3.974	2.781	2.34	1.584	2.19	2.244	728	514	318	214	341	301	AHCTF1	AT-hook containing transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:24618]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K25129	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome"	GO:0003677//DNA binding	GO:0006913//nucleocytoplasmic transport;GO:0007049//cell cycle;GO:0015031//protein transport;GO:0032465//regulation of cytokinesis;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly;GO:0051301//cell division	Others
ENSG00000153208	14.332	13.478	16.74	16.324	16.63	23.065	1045	1010	915	906	1049	1248	MERTK	"MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016028//rhabdomere;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001779//natural killer cell differentiation;GO:0001818//negative regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030168//platelet activation;GO:0032940//secretion by cell;GO:0033674//positive regulation of kinase activity;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043277//apoptotic cell clearance;GO:0043491//protein kinase B signaling;GO:0050766//positive regulation of phagocytosis;GO:0051250//negative regulation of lymphocyte activation;GO:0060041//retina development in camera-type eye;GO:0060068//vagina development;GO:0097350//neutrophil clearance;GO:2000107//negative regulation of leukocyte apoptotic process	--
ENSG00000153214	2.428	2.639	3.342	2.181	2.089	2.144	260	256	197	173	189	167	TMEM87B	transmembrane protein 87B [Source:HGNC Symbol;Acc:HGNC:25913]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	-	"GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000153230	0	0	0	0	0	0	0	0	0	0	0	0	OR14K1	olfactory receptor family 14 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:15025]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000153233	0.646	0.802	0.223	0.198	0.152	0.101	34	44	9	8	7	4	PTPRR	protein tyrosine phosphatase receptor type R [Source:HGNC Symbol;Acc:HGNC:9680]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04458	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding	GO:0001701//in utero embryonic development;GO:0006470//protein dephosphorylation;GO:0010633//negative regulation of epithelial cell migration;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0038128//ERBB2 signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000153234	0.246	0.29	0.296	0.231	0.043	0.14	10	12	13	11	2	7	NR4A2	nuclear receptor subfamily 4 group A member 2 [Source:HGNC Symbol;Acc:HGNC:7981]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action;ko04925//Aldosterone synthesis and secretion"	K08558;K08558	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0035259//glucocorticoid receptor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0001764//neuron migration;GO:0001975//response to amphetamine;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008344//adult locomotory behavior;GO:0009791//post-embryonic development;GO:0010467//gene expression;GO:0010468//regulation of gene expression;GO:0021952//central nervous system projection neuron axonogenesis;GO:0021953//central nervous system neuron differentiation;GO:0021986//habenula development;GO:0030182//neuron differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0034599//cellular response to oxidative stress;GO:0042053//regulation of dopamine metabolic process;GO:0042416//dopamine biosynthetic process;GO:0042417//dopamine metabolic process;GO:0042551//neuron maturation;GO:0043085//positive regulation of catalytic activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043576//regulation of respiratory gaseous exchange;GO:0045444//fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050896//response to stimulus;GO:0051866//general adaptation syndrome;GO:0060070//canonical Wnt signaling pathway;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0071542//dopaminergic neuron differentiation;GO:1904948//midbrain dopaminergic neuron differentiation;GO:2001234//negative regulation of apoptotic signaling pathway"	NGFIB-like
ENSG00000153237	0.871	1.035	1.15	0.663	0.931	0.854	34	44	35	16	33	22	CCDC148	coiled-coil domain containing 148 [Source:HGNC Symbol;Acc:HGNC:25191]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000153246	5.858	4.566	3.806	2.56	3.621	3.55	829	638	386	292	457	355	PLA2R1	phospholipase A2 receptor 1 [Source:HGNC Symbol;Acc:HGNC:9042]	Human Diseases;Cellular Processes	Infectious disease: bacterial;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome	K06560;K06560	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0043274//phospholipase binding	"GO:0001819//positive regulation of cytokine production;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0072593//reactive oxygen species metabolic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0090399//replicative senescence;GO:0090403//oxidative stress-induced premature senescence;GO:1900138//negative regulation of phospholipase A2 activity;GO:1900139//negative regulation of arachidonic acid secretion;GO:1904635//positive regulation of glomerular visceral epithelial cell apoptotic process"	--
ENSG00000153250	23.27	19.065	18.27	15.167	18.481	19.601	1594	1256	944	757	1013	934	RBMS1	RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	GO:0006260//DNA replication;GO:0006396//RNA processing	--
ENSG00000153253	0.061	0.077	0.081	0.012	0	0.032	7	14	8	1	0	2	SCN3A	sodium voltage-gated channel alpha subunit 3 [Source:HGNC Symbol;Acc:HGNC:10590]	Organismal Systems	Sensory system	ko04742//Taste transduction	K04836	GO:0001518//voltage-gated sodium channel complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000153266	0	0	0	0	0	0	0	0	0	0	0	0	FEZF2	FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506]	-	-	-	-	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007413//axonal fasciculation;GO:0007626//locomotory behavior;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0016358//dendrite development;GO:0021537//telencephalon development;GO:0021542//dentate gyrus development;GO:0021797//forebrain anterior/posterior pattern specification;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0021895//cerebral cortex neuron differentiation;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0043697//cell dedifferentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048664//neuron fate determination;GO:0050767//regulation of neurogenesis;GO:1902667//regulation of axon guidance"	zf-C2H2
ENSG00000153283	0.075	0.023	0	0.032	0	0.348	4	2	0	1	0	3	CD96	CD96 molecule [Source:HGNC Symbol;Acc:HGNC:16892]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0002728//negative regulation of natural killer cell cytokine production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0032496//response to lipopolysaccharide;GO:0032689//negative regulation of interferon-gamma production	--
ENSG00000153291	3.89	1.956	4.069	3.863	5.355	5.957	109	52	65	52	98	87	SLC25A27	solute carrier family 25 member 27 [Source:HGNC Symbol;Acc:HGNC:21065]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0009409//response to cold	--
ENSG00000153292	0.023	0	0	0.27	0.027	0	1	0	0	3	1	0	ADGRF1	adhesion G protein-coupled receptor F1 [Source:HGNC Symbol;Acc:HGNC:18990]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007416//synapse assembly;GO:0007613//memory;GO:0031175//neuron projection development;GO:0032793//positive regulation of CREB transcription factor activity	--
ENSG00000153294	0.015	0	0.042	0	0	0.065	1	0	2	0	0	3	ADGRF4	adhesion G protein-coupled receptor F4 [Source:HGNC Symbol;Acc:HGNC:19011]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000153303	0	0	0	0	0	0	0	0	0	0	0	0	FRMD1	FERM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21240]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16821;K16821	GO:0005856//cytoskeleton;GO:0098592//cytoplasmic side of apical plasma membrane	GO:0005515//protein binding	GO:0035332//positive regulation of hippo signaling	--
ENSG00000153310	15.555	12.586	12.276	11.587	11.78	13.828	658	603	431	396	467	485	CYRIB	CYFIP related Rac1 interactor B [Source:HGNC Symbol;Acc:HGNC:25216]	-	-	-	-	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005929//cilium;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0023030//MHC class Ib protein binding, via antigen binding groove;GO:0031267//small GTPase binding"	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0030334//regulation of cell migration;GO:0030833//regulation of actin filament polymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0032729//positive regulation of interferon-gamma production;GO:0048583//regulation of response to stimulus;GO:0050870//positive regulation of T cell activation;GO:0050920//regulation of chemotaxis;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0071219//cellular response to molecule of bacterial origin;GO:0090140//regulation of mitochondrial fission;GO:2000114//regulation of establishment of cell polarity;GO:2000568//positive regulation of memory T cell activation	--
ENSG00000153317	15.709	12.981	12.019	12.197	13.535	12.005	1519	1372	811	818	1118	975	ASAP1	"ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:2720]"	Cellular Processes;Organismal Systems	Transport and catabolism;Immune system	ko04144//Endocytosis;ko04666//Fc gamma R-mediated phagocytosis	K12488;K12488	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031253//cell projection membrane;GO:0043197//dendritic spine	"GO:0001786//phosphatidylserine binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding"	GO:0030030//cell projection organization;GO:0043547//positive regulation of GTPase activity;GO:0060271//cilium assembly;GO:0061000//negative regulation of dendritic spine development;GO:0071803//positive regulation of podosome assembly;GO:1903527//positive regulation of membrane tubulation	--
ENSG00000153339	10.332	7.352	7.012	5.798	6.068	7.666	1064	751	567	445	512	568	TRAPPC8	trafficking protein particle complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:29169]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0031410//cytoplasmic vesicle;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0016192//vesicle-mediated transport;GO:0034497//protein localization to phagophore assembly site;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000153347	0.937	0.809	0.569	0.405	0.222	0.258	26	26	10	5	6	6	FAM81B	family with sequence similarity 81 member B [Source:HGNC Symbol;Acc:HGNC:26335]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000153391	19.771	22.393	23.321	23.091	23.762	22.297	361	433	333	316.94	357	292	INO80C	INO80 complex subunit C [Source:HGNC Symbol;Acc:HGNC:26994]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex;GO:0071339//MLL1 complex	GO:0005515//protein binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000153395	24.274	27.682	24.262	22.695	24.544	21.468	1987	2279	1467	1377	1699	1281	LPCAT1	lysophosphatidylcholine acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25718]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism	K13510;K13510;K13510	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005509//calcium ion binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047159//1-alkenylglycerophosphocholine O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0047191//1-alkylglycerophosphocholine O-acyltransferase activity;GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0050200//plasmalogen synthase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0043129//surfactant homeostasis;GO:0045732//positive regulation of protein catabolic process;GO:0060041//retina development in camera-type eye;GO:2001246//negative regulation of phosphatidylcholine biosynthetic process	--
ENSG00000153404	3.829	3.566	3.497	2.476	3.692	3.482	591	551	398.05	368	447	369	PLEKHG4B	pleckstrin homology and RhoGEF domain containing G4B [Source:HGNC Symbol;Acc:HGNC:29399]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000153406	19.518	23.059	22.88	21.077	26.576	20.752	473	551	396	374	523	367	NMRAL1	NmrA like redox sensor 1 [Source:HGNC Symbol;Acc:HGNC:24987]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000153443	8.48	7.783	7.764	8.556	9.938	9.955	242	213	154	177	227	201	UBALD1	UBA like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29576]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000153446	0.035	0.324	0.048	0.202	0.155	0.036	1	10	1	5	4	1	C16orf89	chromosome 16 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:28687]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0042803//protein homodimerization activity	-	--
ENSG00000153485	9.902	9.083	11.268	12.349	13.9	10.95	207	209	186	209	256.92	181	TMEM251	transmembrane protein 251 [Source:HGNC Symbol;Acc:HGNC:20218]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000153487	4.394	6.322	5.89	6.001	7.347	6.244	241	288	210	221	246	217	ING1	inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062]	-	-	-	-	GO:0005634//nucleus;GO:0016580//Sin3 complex	GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010941//regulation of cell death;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000153495	0	0	0	0	0	0	0	0	0	0	0	0	TEX29	testis expressed 29 [Source:HGNC Symbol;Acc:HGNC:20370]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000153498	0	0	0	0	0	0	0	0	0	0	0	0	SPACA7	sperm acrosome associated 7 [Source:HGNC Symbol;Acc:HGNC:29575]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0031410//cytoplasmic vesicle;GO:0043160//acrosomal lumen	-	GO:0007338//single fertilization	--
ENSG00000153531	0.392	0.475	0.487	0.626	0.365	0.41	21	18	14	22	17	13	ADPRHL1	ADP-ribosylhydrolase like 1 [Source:HGNC Symbol;Acc:HGNC:21303]	-	-	-	-	GO:0030017//sarcomere	"GO:0000287//magnesium ion binding;GO:0003875//ADP-ribosylarginine hydrolase activity;GO:0016787//hydrolase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds"	GO:0003242//cardiac chamber ballooning;GO:0006464//cellular protein modification process;GO:0051725//protein de-ADP-ribosylation;GO:0055003//cardiac myofibril assembly	--
ENSG00000153551	11.943	11.859	18.31	16.835	17.379	22.311	372	355	371.08	368	430.07	442	CMTM7	CKLF like MARVEL transmembrane domain containing 7 [Source:HGNC Symbol;Acc:HGNC:19178]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0002337//B-1a B cell differentiation;GO:0006935//chemotaxis;GO:0007165//signal transduction	--
ENSG00000153558	17.442	15.149	14.055	13.383	12.035	15.784	868	781	533	504	612	548	FBXL2	F-box and leucine rich repeat protein 2 [Source:HGNC Symbol;Acc:HGNC:13598]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019903//protein phosphatase binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0010506//regulation of autophagy;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044830//modulation by host of viral RNA genome replication	--
ENSG00000153560	23.682	22.875	26.084	22.711	24.963	23.293	1739	1621	1342	1177	1447	1195	UBP1	upstream binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12507]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001525//angiogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032897//negative regulation of viral transcription;GO:0045944//positive regulation of transcription by RNA polymerase II	CP2
ENSG00000153561	19.267	17.074	18.222	14.937	15.671	21.315	2471	2201	1726	1419	1698	1989	RMND5A	required for meiotic nuclear division 5 homolog A [Source:HGNC Symbol;Acc:HGNC:25850]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0034657//GID complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000153563	0	0.049	0.099	0.033	0.029	0.067	0	2	3	1	1	2	CD8A	CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Immune disease;Immune system;Immune system	ko05135//Yersinia infection;ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04660//T cell receptor signaling pathway;ko04612//Antigen processing and presentation	K06458;K06458;K06458;K06458;K06458;K06458	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042101//T cell receptor complex;GO:0043235//receptor complex;GO:0044853//plasma membrane raft	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0019901//protein kinase binding;GO:0023024//MHC class I protein complex binding;GO:0042288//MHC class I protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019882//antigen processing and presentation;GO:0042110//T cell activation;GO:0045065//cytotoxic T cell differentiation;GO:0050852//T cell receptor signaling pathway	--
ENSG00000153574	2.925	3.968	3.889	3.518	3.462	3.728	110	150	108	98	110	102	RPIA	ribose 5-phosphate isomerase A [Source:HGNC Symbol;Acc:HGNC:10297]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K01807;K01807;K01807;K01807	GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004751//ribose-5-phosphate isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0048029//monosaccharide binding	"GO:0006014//D-ribose metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019693//ribose phosphate metabolic process"	--
ENSG00000153684	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA8F	golgin A8 family member F [Source:HGNC Symbol;Acc:HGNC:32378]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000153707	24.741	21.148	23.586	16.083	19.653	21.504	3229	2687	2163	1493	1916	1852	PTPRD	protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0050839//cell adhesion molecule binding	GO:0006470//protein dephosphorylation;GO:0006796//phosphate-containing compound metabolic process;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0016043//cellular component organization;GO:0016311//dephosphorylation;GO:0030182//neuron differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050776//regulation of immune response;GO:0050804//modulation of chemical synaptic transmission;GO:0051965//positive regulation of synapse assembly;GO:0097105//presynaptic membrane assembly;GO:0099151//regulation of postsynaptic density assembly;GO:0099545//trans-synaptic signaling by trans-synaptic complex;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000153714	7.206	6.329	5.547	5.288	4.02	7.434	401	354	228	218	189	301	LURAP1L	leucine rich adaptor protein 1 like [Source:HGNC Symbol;Acc:HGNC:31452]	-	-	-	-	-	GO:0005515//protein binding	GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000153721	9.654	10.862	11.98	9.763	10.634	10.978	731	753.42	567.43	504.23	575.1	517	CNKSR3	CNKSR family member 3 [Source:HGNC Symbol;Acc:HGNC:23034]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane	GO:0005515//protein binding	GO:0009966//regulation of signal transduction;GO:0010765//positive regulation of sodium ion transport;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000153767	4.452	4.162	5.119	4.317	3.329	4.484	277	246	229	199	175	203	GTF2E1	general transcription factor IIE subunit 1 [Source:HGNC Symbol;Acc:HGNC:4650]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors	K03136;K03136	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005673//transcription factor TFIIE complex;GO:0005829//cytosol;GO:0097550//transcription preinitiation complex	GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046872//metal ion binding	GO:0001113//transcription open complex formation at RNA polymerase II promoter;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter	--
ENSG00000153774	47.13	47.219	47.405	41.53	40.338	39.613	1263.99	1272.89	938.99	816.98	913.99	773	CFDP1	craniofacial development protein 1 [Source:HGNC Symbol;Acc:HGNC:1873]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000812//Swr1 complex;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005694//chromosome"	GO:0003674//molecular_function	GO:0006338//chromatin remodeling;GO:0007155//cell adhesion;GO:0008150//biological_process;GO:0008360//regulation of cell shape;GO:0042127//regulation of cell population proliferation;GO:2000270//negative regulation of fibroblast apoptotic process	--
ENSG00000153779	0	0	0	0	0	0	0	0	0	0	0	0	TGIF2LX	TGFB induced factor homeobox 2 like X-linked [Source:HGNC Symbol;Acc:HGNC:18570]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000153786	21.909	21.311	23.576	26.028	24.229	26.557	1500	1441	1174	1224	1394	1335	ZDHHC7	zinc finger DHHC-type palmitoyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:18459]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009895//negative regulation of catabolic process;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0030859//polarized epithelial cell differentiation;GO:0044381//glucose import in response to insulin stimulus;GO:0150106//regulation of protein localization to cell-cell junction;GO:1902044//regulation of Fas signaling pathway;GO:1903076//regulation of protein localization to plasma membrane	--
ENSG00000153789	0.156	0.358	0.306	0.129	0.073	0	4	7	6	2	1	0	CIBAR2	CBY1 interacting BAR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24781]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000153790	4.607	4.205	4.332	2.669	2.515	4.075	248	196	142	110	130	130	C7orf31	chromosome 7 open reading frame 31 [Source:HGNC Symbol;Acc:HGNC:21722]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000153802	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS11D	transmembrane serine protease 11D [Source:HGNC Symbol;Acc:HGNC:24059]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K09641	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007585//respiratory gaseous exchange by respiratory system	--
ENSG00000153814	10.928	10.033	8.649	11.476	8.753	11.954	687	647.97	419	485.99	480	558	JAZF1	JAZF zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:28917]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0017053//transcription repressor complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process	zf-C2H2
ENSG00000153815	7.095	7.979	7.604	6.992	8.278	6.587	513	570	381	391	506	380	CMIP	c-Maf inducing protein [Source:HGNC Symbol;Acc:HGNC:24319]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0001701//in utero embryonic development	--
ENSG00000153820	0.184	0.147	0.077	0.277	0.411	0.487	26	21	8	29	49	50	SPHKAP	"SPHK1 interactor, AKAP domain containing [Source:HGNC Symbol;Acc:HGNC:30619]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0051018//protein kinase A binding	-	--
ENSG00000153822	0.013	0	0	0.053	0	0.036	1	0	0	3	0	2	KCNJ16	potassium inwardly rectifying channel subfamily J member 16 [Source:HGNC Symbol;Acc:HGNC:6262]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K05009	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000153823	2.589	1.932	1.43	1.502	1.195	2.065	138	103	56	59	54	80	PID1	phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006112//energy reserve metabolic process;GO:0010628//positive regulation of gene expression;GO:0010635//regulation of mitochondrial fusion;GO:0042127//regulation of cell population proliferation;GO:0044320//cellular response to leptin stimulus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0051881//regulation of mitochondrial membrane potential;GO:0070346//positive regulation of fat cell proliferation;GO:0070584//mitochondrion morphogenesis;GO:0071345//cellular response to cytokine stimulus;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0071398//cellular response to fatty acid;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2001170//negative regulation of ATP biosynthetic process;GO:2001171//positive regulation of ATP biosynthetic process	--
ENSG00000153827	31.991	27.666	29.73	19.77	21.667	23.19	3984	3518	2557	1942	2400	2148	TRIP12	thyroid hormone receptor interactor 12 [Source:HGNC Symbol;Acc:HGNC:12306]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10590	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046966//thyroid hormone receptor binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0045995//regulation of embryonic development;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:2000779//regulation of double-strand break repair;GO:2000780//negative regulation of double-strand break repair	--
ENSG00000153832	3.241	3.257	3.296	2.364	2.566	2.486	190	191	143	104	127	106	FBXO36	F-box protein 36 [Source:HGNC Symbol;Acc:HGNC:27020]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000153879	5.7	5.481	5.307	4.31	4.024	9.717	441	423	292	247	263	547	CEBPG	CCAAT enhancer binding protein gamma [Source:HGNC Symbol;Acc:HGNC:1837]	Human Diseases	Infectious disease: bacterial	ko05152//Tuberculosis	K10049	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001889//liver development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006955//immune response;GO:0016071//mRNA metabolic process;GO:0030183//B cell differentiation;GO:0032729//positive regulation of interferon-gamma production;GO:0042267//natural killer cell mediated cytotoxicity;GO:0043353//enucleate erythrocyte differentiation;GO:0043388//positive regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045739//positive regulation of DNA repair;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000153885	10.612	9.698	8.747	7.941	8.291	9.301	606	541	400	342	444	453	KCTD15	potassium channel tetramerization domain containing 15 [Source:HGNC Symbol;Acc:HGNC:23297]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0051260//protein homooligomerization	--
ENSG00000153896	5.306	5.363	6.471	6.451	5.614	5.707	162	171	149	148	165	134	ZNF599	zinc finger protein 599 [Source:HGNC Symbol;Acc:HGNC:26408]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000153898	1.853	1.571	1.566	1.461	1.937	3.169	117	86	71	61	93	141	MCOLN2	mucolipin TRP cation channel 2 [Source:HGNC Symbol;Acc:HGNC:13357]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K04993	GO:0005764//lysosome;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0042802//identical protein binding;GO:0072345//NAADP-sensitive calcium-release channel activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0015031//protein transport;GO:0032722//positive regulation of chemokine production;GO:0034220//ion transmembrane transport;GO:0045087//innate immune response;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0071642//positive regulation of macrophage inflammatory protein 1 alpha production;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0098655//cation transmembrane transport;GO:1905517//macrophage migration;GO:1990266//neutrophil migration;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000153902	1.006	1.049	1.517	1.307	1.662	1.841	59	59	58	55	69	59	LGI4	leucine rich repeat LGI family member 4 [Source:HGNC Symbol;Acc:HGNC:18712]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0008344//adult locomotory behavior;GO:0014009//glial cell proliferation;GO:0014044//Schwann cell development;GO:0021782//glial cell development;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0042063//gliogenesis;GO:0042551//neuron maturation;GO:0042552//myelination	--
ENSG00000153904	52.193	51.193	50.984	48.225	46.916	52.576	4250	4210	3080	2877	3209	3131	DDAH1	dimethylarginine dimethylaminohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:2715]	-	-	-	-	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0016403//dimethylargininase activity;GO:0016597//amino acid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000052//citrulline metabolic process;GO:0003073//regulation of systemic arterial blood pressure;GO:0006525//arginine metabolic process;GO:0006527//arginine catabolic process;GO:0007263//nitric oxide mediated signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0043116//negative regulation of vascular permeability;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0050999//regulation of nitric-oxide synthase activity;GO:1900038//negative regulation of cellular response to hypoxia	--
ENSG00000153914	6.744	6.233	4.909	3.891	4.402	6.735	502	430	294	216	305	347	SREK1	splicing regulatory glutamic acid and lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:17882]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000153922	5.427	3.72	3.332	3.277	4.015	3.445	533	376	253	183	239	211	CHD1	chromodomain helicase DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1915]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035064//methylated histone binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0032508//DNA duplex unwinding;GO:0043923//positive regulation by host of viral transcription	--
ENSG00000153930	0	0	0	0	0	0.014	0	0	0	0	0	2	ANKFN1	ankyrin repeat and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26766]	-	-	-	-	GO:0005819//spindle	GO:0005515//protein binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001662//behavioral fear response;GO:0045475//locomotor rhythm;GO:0050957//equilibrioception;GO:0061172//regulation of establishment of bipolar cell polarity	--
ENSG00000153933	0.961	1.01	1.415	0.951	1.729	1.169	163	116	143	106	158	136	DGKE	diacylglycerol kinase epsilon [Source:HGNC Symbol;Acc:HGNC:2852]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0044255//cellular lipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0050804//modulation of chemical synaptic transmission	--
ENSG00000153936	27.85	24.015	24.775	18.519	18.611	20.997	2875	2450.17	1906.46	1427	1611	1549	HS2ST1	heparan sulfate 2-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5193]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02513	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0004394//heparan sulfate 2-O-sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification"	--
ENSG00000153944	44.014	42.719	39.807	34.241	36.703	42.024	4388	3926	2805	2424	2833	2709	MSI2	musashi RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:18585]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14411	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding	GO:0048864//stem cell development	--
ENSG00000153956	3.995	2.972	2.099	1.564	2.393	1.472	424	288	180	118	164	114	CACNA2D1	calcium voltage-gated channel auxiliary subunit alpha2delta 1 [Source:HGNC Symbol;Acc:HGNC:1399]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04858;K04858;K04858;K04858;K04858;K04858;K04858	GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030315//T-tubule;GO:0070062//extracellular exosome;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0086007//voltage-gated calcium channel activity involved in cardiac muscle cell action potential;GO:0086057//voltage-gated calcium channel activity involved in bundle of His cell action potential	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051924//regulation of calcium ion transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060402//calcium ion transport into cytosol;GO:0061577//calcium ion transmembrane transport via high voltage-gated calcium channel;GO:0070588//calcium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086048//membrane depolarization during bundle of His cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098703//calcium ion import across plasma membrane;GO:0098903//regulation of membrane repolarization during action potential;GO:1901843//positive regulation of high voltage-gated calcium channel activity;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:1904646//cellular response to amyloid-beta	--
ENSG00000153975	3.231	3.794	2.905	2.334	2.71	3.189	132	156	88	76	91	99	ZUP1	zinc finger containing ubiquitin peptidase 1 [Source:HGNC Symbol;Acc:HGNC:21224]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0010468//regulation of gene expression	--
ENSG00000153976	1.957	1.042	1.828	1.752	0.946	1.942	106.1	74.92	43.2	52.46	56.53	60.49	HS3ST3A1	heparan sulfate-glucosamine 3-sulfotransferase 3A1 [Source:HGNC Symbol;Acc:HGNC:5196]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K07809	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity;GO:0033872//[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000153982	3.051	2.126	2.356	2.028	3.158	2.602	96	88	61	58	87	72	GDPD1	glycerophosphodiester phosphodiesterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20883]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K22387;K22387	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004622//lysophospholipase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0070291//N-acylethanolamine metabolic process	--
ENSG00000153989	17.903	16.212	16.197	13.707	14.587	16.178	1781	1621	1190	1010	1226	1171	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit [Source:HGNC Symbol;Acc:HGNC:21042]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K19177	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1904423//dehydrodolichyl diphosphate synthase complex	"GO:0004659//prenyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0045547//dehydrodolichyl diphosphate synthase activity;GO:0046872//metal ion binding"	GO:0001525//angiogenesis;GO:0006486//protein glycosylation;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0006629//lipid metabolic process;GO:0019408//dolichol biosynthetic process;GO:0030154//cell differentiation;GO:0032383//regulation of intracellular cholesterol transport;GO:0035268//protein mannosylation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0042632//cholesterol homeostasis;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0055092//sterol homeostasis	--
ENSG00000153993	3.51	2.054	2.675	1.73	1.896	2.221	493	272	255	180	225	227	SEMA3D	semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000154001	11.911	10.353	9.721	8.815	9.148	8.323	1046	856	623	536	632	557	PPP2R5E	protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313]	Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Cell growth and death;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11584;K11584;K11584;K11584;K11584;K11584;K11584;K11584	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000154007	0	0	0	0	0	0	0	0	0	0	0	0	ASB17	ankyrin repeat and SOCS box containing 17 [Source:HGNC Symbol;Acc:HGNC:19769]	-	-	-	-	GO:0005829//cytosol	-	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000154016	0	0.072	0	0	0.23	0	0	3	0	0	8	0	GRAP	GRB2 related adaptor protein [Source:HGNC Symbol;Acc:HGNC:4562]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding	GO:0007265//Ras protein signal transduction;GO:0007267//cell-cell signaling;GO:0007605//sensory perception of sound	--
ENSG00000154025	0	0	0	0.016	0.058	0.015	0	0	0	1	2.01	1	SLC5A10	solute carrier family 5 member 10 [Source:HGNC Symbol;Acc:HGNC:23155]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005412//glucose:sodium symporter activity;GO:0015370//solute:sodium symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008645//hexose transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000154027	7.937	8.525	10.69	12.697	11.761	13.913	540	583	494	641	676	608	AK5	adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006172//ADP biosynthetic process;GO:0006173//dADP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0009220//pyrimidine ribonucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0046034//ATP metabolic process;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000154040	2.938	3.359	2.606	1.679	2.374	1.558	95	117	65	41	67	42	CABYR	calcium binding tyrosine phosphorylation regulated [Source:HGNC Symbol;Acc:HGNC:15569]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0048240//sperm capacitation	--
ENSG00000154059	12.473	13.937	14.531	11.176	12.439	13.939	963	795	673	569	728	666	IMPACT	impact RWD domain protein [Source:HGNC Symbol;Acc:HGNC:20387]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005844//polysome	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001933//negative regulation of protein phosphorylation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0007399//nervous system development;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031953//negative regulation of protein autophosphorylation;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0045666//positive regulation of neuron differentiation;GO:0060548//negative regulation of cell death;GO:0070301//cellular response to hydrogen peroxide;GO:0071264//positive regulation of translational initiation in response to starvation;GO:0071468//cellular response to acidic pH;GO:0071494//cellular response to UV-C;GO:0072755//cellular response to benomyl;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:0140469//GCN2-mediated signaling;GO:1990138//neuron projection extension;GO:1990253//cellular response to leucine starvation	--
ENSG00000154065	3.217	2.956	2.892	4.405	3.137	3.827	150	139	106	154	128	122	ANKRD29	ankyrin repeat domain 29 [Source:HGNC Symbol;Acc:HGNC:27110]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000154079	3.464	3.609	3.863	3.466	4.534	3.585	85	89	70	63	94	64	SDHAF4	succinate dehydrogenase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:20957]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0034553//mitochondrial respiratory chain complex II assembly;GO:0045087//innate immune response;GO:0045333//cellular respiration;GO:1904231//positive regulation of succinate dehydrogenase activity	--
ENSG00000154080	0.34	0.313	0.064	0.032	0.166	0.163	17	20	2	1	10	5	CHST9	carbohydrate sulfotransferase 9 [Source:HGNC Symbol;Acc:HGNC:19898]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00513//Various types of N-glycan biosynthesis	K09673;K09673	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047756//chondroitin 4-sulfotransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006790//sulfur compound metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0042446//hormone biosynthetic process	--
ENSG00000154096	9.623	15.873	4.904	10.244	9.933	6.572	262	404	92	179	204	118	THY1	Thy-1 cell surface antigen [Source:HGNC Symbol;Acc:HGNC:11801]	Organismal Systems	Immune system	ko04670//Leukocyte transendothelial migration	K06514	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030673//axolemma;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome	GO:0005096//GTPase activator activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0034235//GPI anchor binding	GO:0001525//angiogenesis;GO:0001952//regulation of cell-matrix adhesion;GO:0002693//positive regulation of cellular extravasation;GO:0006469//negative regulation of protein kinase activity;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0030334//regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0043113//receptor clustering;GO:0043547//positive regulation of GTPase activity;GO:0046549//retinal cone cell development;GO:0046777//protein autophosphorylation;GO:0048041//focal adhesion assembly;GO:0050771//negative regulation of axonogenesis;GO:0050852//T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051894//positive regulation of focal adhesion assembly;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0070571//negative regulation of neuron projection regeneration;GO:0098609//cell-cell adhesion;GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity	--
ENSG00000154099	0.303	0.522	0.318	0.305	0.072	0.111	15	26	11	8	3	4	DNAAF1	dynein axonemal assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30539]	-	-	-	-	GO:0000922//spindle pole;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016607//nuclear speck;GO:0042995//cell projection	GO:0005515//protein binding;GO:0070840//dynein complex binding	GO:0001947//heart looping;GO:0003341//cilium movement;GO:0003356//regulation of cilium beat frequency;GO:0030324//lung development;GO:0035469//determination of pancreatic left/right asymmetry;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0044458//motile cilium assembly;GO:0060271//cilium assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0060972//left/right pattern formation;GO:0070286//axonemal dynein complex assembly;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry	--
ENSG00000154102	3.261	3.587	5.152	5.322	4.764	3.547	60	68	67	71	75	47	C16orf74	chromosome 16 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:23362]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000154114	6.206	5.681	5.924	5.093	5.756	6.238	628.26	512.28	404.81	346.25	444.32	431	TBCEL	tubulin folding cofactor E like [Source:HGNC Symbol;Acc:HGNC:28115]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0043014//alpha-tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway	--
ENSG00000154118	0.209	0.394	0.298	0.356	0.273	0.333	19	36	20	24	21	22	JPH3	junctophilin 3 [Source:HGNC Symbol;Acc:HGNC:14203]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030314//junctional membrane complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007612//learning;GO:0007613//memory;GO:0035640//exploration behavior;GO:0040011//locomotion;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0050885//neuromuscular process controlling balance;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060402//calcium ion transport into cytosol	--
ENSG00000154122	8.8	7.931	8.519	8.676	9.109	8.8	1498	1357	1071	1094	1310	1090	ANKH	ANKH inorganic pyrophosphate transport regulator [Source:HGNC Symbol;Acc:HGNC:15492]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019867//outer membrane	GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0015114//phosphate ion transmembrane transporter activity;GO:0030504//inorganic diphosphate transmembrane transporter activity	GO:0001501//skeletal system development;GO:0006817//phosphate ion transport;GO:0007626//locomotory behavior;GO:0010467//gene expression;GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0030505//inorganic diphosphate transport;GO:0035435//phosphate ion transmembrane transport;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0071344//diphosphate metabolic process;GO:0071529//cementum mineralization;GO:0110148//biomineralization;GO:1904383//response to sodium phosphate	--
ENSG00000154124	3.604	3.537	6.462	3.654	5.042	7.142	438	377	341	251	354	345	OTULIN	OTU deubiquitinase with linear linkage specificity [Source:HGNC Symbol;Acc:HGNC:25118]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071797//LUBAC complex	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001525//angiogenesis;GO:0002040//sprouting angiogenesis;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045087//innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:1990108//protein linear deubiquitination	--
ENSG00000154127	0.155	0.126	0.181	0.114	0.058	0.135	22	18	19	12	7	14	UBASH3B	ubiquitin associated and SH3 domain containing B [Source:HGNC Symbol;Acc:HGNC:29884]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0051219//phosphoprotein binding	GO:0006469//negative regulation of protein kinase activity;GO:0009968//negative regulation of signal transduction;GO:0030168//platelet activation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0038065//collagen-activated signaling pathway;GO:0043393//regulation of protein binding;GO:0045670//regulation of osteoclast differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0070527//platelet aggregation;GO:0090331//negative regulation of platelet aggregation	--
ENSG00000154133	0.048	0.045	0.043	0.03	0.053	0.108	4	4	2	2	4	7	ROBO4	roundabout guidance receptor 4 [Source:HGNC Symbol;Acc:HGNC:17985]	-	-	-	-	GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0098632//cell-cell adhesion mediator activity	GO:0001525//angiogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0061028//establishment of endothelial barrier;GO:0070593//dendrite self-avoidance	--
ENSG00000154134	0.228	0.458	0.413	0.493	0.292	0.457	8	25	13	14	13	30	ROBO3	roundabout guidance receptor 3 [Source:HGNC Symbol;Acc:HGNC:13433]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06755	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0006935//chemotaxis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0016199//axon midline choice point recognition;GO:0030154//cell differentiation;GO:0070593//dendrite self-avoidance	--
ENSG00000154143	0	0.028	0	0	0	0	0	1	0	0	0	0	PANX3	pannexin 3 [Source:HGNC Symbol;Acc:HGNC:20573]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0015267//channel activity;GO:0022829//wide pore channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0007267//cell-cell signaling;GO:0032732//positive regulation of interleukin-1 production;GO:0055085//transmembrane transport	--
ENSG00000154144	7.775	7.059	7.376	3.887	6.03	7.428	420.96	393.39	253.26	217.77	327.6	317.02	TBRG1	transforming growth factor beta regulator 1 [Source:HGNC Symbol;Acc:HGNC:29551]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0050821//protein stabilization;GO:0051726//regulation of cell cycle;GO:1990173//protein localization to nucleoplasm	--
ENSG00000154146	0.087	0	0.236	0.177	0	0	2	0	4	3	0	0	NRGN	neurogranin [Source:HGNC Symbol;Acc:HGNC:8000]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0014069//postsynaptic density;GO:0030424//axon;GO:0030425//dendrite;GO:0031966//mitochondrial membrane;GO:0043025//neuronal cell body;GO:0044327//dendritic spine head;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	"GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0016301//kinase activity;GO:0070300//phosphatidic acid binding"	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008306//associative learning;GO:0016310//phosphorylation;GO:0021537//telencephalon development;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:1900273//positive regulation of long-term synaptic potentiation	--
ENSG00000154153	5.369	5.465	3.324	3.772	3.4	3.688	283	295	147	148	159	134	RETREG1	reticulophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:25964]	-	-	-	-	GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding	GO:0000423//mitophagy;GO:0006914//autophagy;GO:0019233//sensory perception of pain;GO:0043524//negative regulation of neuron apoptotic process;GO:0050872//white fat cell differentiation;GO:0061709//reticulophagy	--
ENSG00000154162	0.473	0.27	0.461	0.241	0.206	0.107	37	24	30	14	15	6	CDH12	cadherin 12 [Source:HGNC Symbol;Acc:HGNC:1751]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000154165	0	0	0	0	0	0	0	0	0	0	0	0	GPR15	G protein-coupled receptor 15 [Source:HGNC Symbol;Acc:HGNC:4469]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0046718//viral entry into host cell;GO:0072678//T cell migration	--
ENSG00000154174	19.038	16.308	16.51	13.811	15.254	16.743	1619	1394	1037	870	1096	1036	TOMM70	translocase of outer mitochondrial membrane 70 [Source:HGNC Symbol;Acc:HGNC:11985]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0030943//mitochondrion targeting sequence binding	GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0006626//protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix;GO:0032728//positive regulation of interferon-beta production;GO:0042981//regulation of apoptotic process;GO:0045039//protein insertion into mitochondrial inner membrane;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0097068//response to thyroxine;GO:0098586//cellular response to virus;GO:1904591//positive regulation of protein import	--
ENSG00000154175	1.105	1.514	0.931	0.654	1.407	0.522	29	40	24	11	19	10	ABI3BP	ABI family member 3 binding protein [Source:HGNC Symbol;Acc:HGNC:17265]	-	-	-	-	GO:0005576//extracellular region;GO:0005614//interstitial matrix;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding	GO:0008285//negative regulation of cell population proliferation;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:1904597//negative regulation of connective tissue replacement involved in inflammatory response wound healing;GO:1905209//positive regulation of cardiocyte differentiation	--
ENSG00000154188	0.111	0.068	0.129	0	0.075	0.097	10	6	3	0	2	4	ANGPT1	angiopoietin 1 [Source:HGNC Symbol;Acc:HGNC:484]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Immune disease;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05323//Rheumatoid arthritis;ko04066//HIF-1 signaling pathway	K05465;K05465;K05465;K05465;K05465;K05465	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002040//sprouting angiogenesis;GO:0002092//positive regulation of receptor internalization;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0007162//negative regulation of cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030210//heparin biosynthetic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031589//cell-substrate adhesion;GO:0032680//regulation of tumor necrosis factor production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034394//protein localization to cell surface;GO:0042308//negative regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043393//regulation of protein binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045785//positive regulation of cell adhesion;GO:0048014//Tie signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0072012//glomerulus vasculature development;GO:1905605//positive regulation of blood-brain barrier permeability;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000446//regulation of macrophage migration inhibitory factor signaling pathway	--
ENSG00000154217	12.914	12.285	13.118	12.275	12.563	14.339	1602	1546	1159	1139	1265	1313	PITPNC1	phosphatidylinositol transfer protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:21045]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transfer activity;GO:0035091//phosphatidylinositol binding;GO:0070300//phosphatidic acid binding;GO:1901611//phosphatidylglycerol binding;GO:1990050//phosphatidic acid transfer activity	GO:0006869//lipid transport;GO:0007165//signal transduction;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000154222	7.98	8.335	8.507	9.924	8.896	8.973	762	782	594	634	676	599	CC2D1B	coiled-coil and C2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:29386]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0005515//protein binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000154227	0.013	0	0	0	0.031	0.036	1	0	0	0	1	2	CERS3	ceramide synthase 3 [Source:HGNC Symbol;Acc:HGNC:23752]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K24622;K24622;K24622	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0008544//epidermis development;GO:0030148//sphingolipid biosynthetic process;GO:0030216//keratinocyte differentiation;GO:0046513//ceramide biosynthetic process;GO:0070268//cornification	--
ENSG00000154229	2.081	2.033	1.995	1.539	2.069	1.523	387	380	274	212	325	206	PRKCA	protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Signal transduction;Signal transduction;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Immune system;Circulatory system;Nervous system;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Cancer: overview;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Substance dependence;Cellular community - eukaryotes;Nervous system;Endocrine system;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Digestive system;Cancer: specific types;Endocrine system;Substance dependence;Nervous system;Endocrine system;Signal transduction;Nervous system;Excretory system;Infectious disease: bacterial;Excretory system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko05231//Choline metabolism in cancer;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko04971//Gastric acid secretion;ko05223//Non-small cell lung cancer;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko04960//Aldosterone-regulated sodium reabsorption"	K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677;K02677	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0035866//alphav-beta3 integrin-PKCalpha complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0035403//histone kinase activity (H3-T6 specific);GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002159//desmosome assembly;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007077//mitotic nuclear membrane disassembly;GO:0007155//cell adhesion;GO:0010595//positive regulation of endothelial cell migration;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030168//platelet activation;GO:0030335//positive regulation of cell migration;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0034351//negative regulation of glial cell apoptotic process;GO:0035408//histone H3-T6 phosphorylation;GO:0035556//intracellular signal transduction;GO:0043488//regulation of mRNA stability;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045651//positive regulation of macrophage differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045780//positive regulation of bone resorption;GO:0045785//positive regulation of cell adhesion;GO:0045931//positive regulation of mitotic cell cycle;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070555//response to interleukin-1;GO:0080090//regulation of primary metabolic process;GO:0090330//regulation of platelet aggregation;GO:0097190//apoptotic signaling pathway;GO:0106071//positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:2000707//positive regulation of dense core granule biogenesis	--
ENSG00000154237	0.084	0.167	0.14	0.21	0.257	0.167	18	44	22	25	34	28	LRRK1	leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0036035//osteoclast development;GO:0045453//bone resorption;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902533//positive regulation of intracellular signal transduction	--
ENSG00000154240	1.621	1.506	1.698	0.876	0.984	1.47	114	106	73	43	53	61	CEP112	centrosomal protein 112 [Source:HGNC Symbol;Acc:HGNC:28514]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0060077//inhibitory synapse	-	GO:0097120//receptor localization to synapse	--
ENSG00000154252	0.332	0.165	0.045	0.717	0.314	0.274	10	5	1	16	8	6	GAL3ST2	galactose-3-O-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:24869]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0001733//galactosylceramide sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0050694//galactose 3-O-sulfotransferase activity	GO:0008150//biological_process;GO:0009101//glycoprotein biosynthetic process;GO:0009247//glycolipid biosynthetic process	--
ENSG00000154258	0	0	0	0	0	0	0	0	0	0	0	0	ABCA9	ATP binding cassette subfamily A member 9 [Source:HGNC Symbol;Acc:HGNC:39]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05651	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0055085//transmembrane transport	--
ENSG00000154262	0	0	0	0.012	0.011	0	0	0	0	1	1	0	ABCA6	ATP binding cassette subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:36]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05649	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0055085//transmembrane transport	--
ENSG00000154263	0.063	0.04	0.011	0.04	0.019	0.027	7	5	1	3	2	2	ABCA10	ATP binding cassette subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:30]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05652	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0055085//transmembrane transport	--
ENSG00000154265	7.778	5.754	5.065	5.936	4.638	3.822	522	369	237	273	291	207	ABCA5	ATP binding cassette subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:35]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05648	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010874//regulation of cholesterol efflux;GO:0030301//cholesterol transport;GO:0033344//cholesterol efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0055085//transmembrane transport;GO:1903064//positive regulation of reverse cholesterol transport	--
ENSG00000154269	0.016	0.062	0	0	0	0.021	1	2	0	0	0	1	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:3358]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00500//Starch and sucrose metabolism;ko00760//Nicotinate and nicotinamide metabolism;ko00770//Pantothenate and CoA biosynthesis;ko00740//Riboflavin metabolism	K01513;K01513;K01513;K01513;K01513;K01513;K01513	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0004528//phosphodiesterase I activity;GO:0004551//nucleotide diphosphatase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0036218//dTTP diphosphatase activity;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity	GO:0002276//basophil activation involved in immune response;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0009143//nucleoside triphosphate catabolic process;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0046034//ATP metabolic process;GO:0050728//negative regulation of inflammatory response;GO:0055062//phosphate ion homeostasis;GO:0070667//negative regulation of mast cell proliferation;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000154274	6.631	5.753	5.672	5.086	4.666	6.672	353	327.56	249.97	202	193.66	259	C4orf19	chromosome 4 open reading frame 19 [Source:HGNC Symbol;Acc:HGNC:25618]	-	-	-	-	GO:0005654//nucleoplasm;GO:0030054//cell junction	GO:0005515//protein binding	-	--
ENSG00000154277	118.877	109.449	99.576	115.332	109.709	107.879	2593	2422	1625	1872	2054	1710	UCHL1	ubiquitin C-terminal hydrolase L1 [Source:HGNC Symbol;Acc:HGNC:12513]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K05611;K05611	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0044306//neuron projection terminus;GO:1904115//axon cytoplasm	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008242//omega peptidase activity;GO:0016787//hydrolase activity;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0031694//alpha-2A adrenergic receptor binding;GO:0043130//ubiquitin binding	GO:0002931//response to ischemia;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007409//axonogenesis;GO:0007412//axon target recognition;GO:0007628//adult walking behavior;GO:0008283//cell population proliferation;GO:0016241//regulation of macroautophagy;GO:0016579//protein deubiquitination;GO:0019233//sensory perception of pain;GO:0019896//axonal transport of mitochondrion;GO:0042755//eating behavior;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0050905//neuromuscular process;GO:0055001//muscle cell development;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000154305	15.282	12.618	11.779	9.398	11.059	9.91	1631	1255	889	641	889	827	MIA3	MIA SH3 domain ER export factor 3 [Source:HGNC Symbol;Acc:HGNC:24008]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding;GO:0038024//cargo receptor activity	GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002687//positive regulation of leukocyte migration;GO:0006887//exocytosis;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0007029//endoplasmic reticulum organization;GO:0007162//negative regulation of cell adhesion;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030336//negative regulation of cell migration;GO:0035459//vesicle cargo loading;GO:0042060//wound healing;GO:0042953//lipoprotein transport;GO:0070973//protein localization to endoplasmic reticulum exit site;GO:0090110//COPII-coated vesicle cargo loading;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:2000402//negative regulation of lymphocyte migration	--
ENSG00000154309	4.185	4.496	4.622	4.163	3.847	5.71	410	443	334	301	319	346	DISP1	dispatched RND transporter family member 1 [Source:HGNC Symbol;Acc:HGNC:19711]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04340//Hedgehog signaling pathway;ko04341//Hedgehog signaling pathway - fly	K24680;K24680	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:1904680//peptide transmembrane transporter activity	GO:0007225//patched ligand maturation;GO:0007368//determination of left/right symmetry;GO:0009880//embryonic pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0015833//peptide transport;GO:0050708//regulation of protein secretion;GO:0060539//diaphragm development;GO:0070207//protein homotrimerization	--
ENSG00000154310	5.312	4.705	3.193	3.651	5.584	5.226	650	560	290	371	581	421	TNIK	TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K08840	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016324//apical plasma membrane;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007399//nervous system development;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0030033//microvillus assembly;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048812//neuron projection morphogenesis;GO:0048814//regulation of dendrite morphogenesis;GO:0072659//protein localization to plasma membrane	--
ENSG00000154319	2.063	2.441	1.774	1.136	1.389	1.394	174	207	92	71	99	67	FAM167A	family with sequence similarity 167 member A [Source:HGNC Symbol;Acc:HGNC:15549]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000154328	7.846	7.962	6.519	6.467	6.239	6.676	360	397	235	238	256	242	NEIL2	nei like DNA glycosylase 2 [Source:HGNC Symbol;Acc:HGNC:18956]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10568	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0072686//mitotic spindle	"GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016829//lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0046872//metal ion binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) endonuclease activity"	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0045008//depyrimidination	--
ENSG00000154330	43.95	45.425	47.663	47.477	47.236	50.563	3291	3434	2643	2645	2997	2767	PGM5	phosphoglucomutase 5 [Source:HGNC Symbol;Acc:HGNC:8908]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005914//spot adherens junction;GO:0005925//focal adhesion;GO:0009898//cytoplasmic side of plasma membrane;GO:0014704//intercalated disc;GO:0016010//dystrophin-associated glycoprotein complex;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0042383//sarcolemma;GO:0043034//costamere	"GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity;GO:0005198//structural molecule activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0007155//cell adhesion;GO:0014706//striated muscle tissue development;GO:0030239//myofibril assembly;GO:0071704//organic substance metabolic process	--
ENSG00000154342	0	0	0	0	0	0	0	0	0	0	0	0	WNT3A	Wnt family member 3A [Source:HGNC Symbol;Acc:HGNC:15983]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312;K00312	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:1990851//Wnt-Frizzled-LRP5/6 complex	GO:0003713//transcription coactivator activity;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0039706//co-receptor binding;GO:0048018//receptor ligand activity	"GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0001819//positive regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0001947//heart looping;GO:0002092//positive regulation of receptor internalization;GO:0003136//negative regulation of heart induction by canonical Wnt signaling pathway;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007498//mesoderm development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0010387//COP9 signalosome assembly;GO:0010628//positive regulation of gene expression;GO:0010977//negative regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0021527//spinal cord association neuron differentiation;GO:0021766//hippocampus development;GO:0021846//cell proliferation in forebrain;GO:0021874//Wnt signaling pathway involved in forebrain neuroblast division;GO:0021904//dorsal/ventral neural tube patterning;GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0030168//platelet activation;GO:0030182//neuron differentiation;GO:0030198//extracellular matrix organization;GO:0030879//mammary gland development;GO:0030890//positive regulation of B cell proliferation;GO:0030901//midbrain development;GO:0032092//positive regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033278//cell proliferation in midbrain;GO:0034613//cellular protein localization;GO:0035914//skeletal muscle cell differentiation;GO:0036342//post-anal tail morphogenesis;GO:0036465//synaptic vesicle recycling;GO:0042472//inner ear morphogenesis;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045165//cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048103//somatic stem cell division;GO:0048337//positive regulation of mesodermal cell fate specification;GO:0048343//paraxial mesodermal cell fate commitment;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048697//positive regulation of collateral sprouting in absence of injury;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050768//negative regulation of neurogenesis;GO:0050770//regulation of axonogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050807//regulation of synapse organization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060070//canonical Wnt signaling pathway;GO:0060923//cardiac muscle cell fate commitment;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0061184//positive regulation of dermatome development;GO:0061317//canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:0062009//secondary palate development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0070527//platelet aggregation;GO:0071300//cellular response to retinoic acid;GO:0090245//axis elongation involved in somitogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090676//calcium ion transmembrane transport via low voltage-gated calcium channel;GO:0099054//presynapse assembly;GO:0099527//postsynapse to nucleus signaling pathway;GO:1901215//negative regulation of neuron death;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904339//negative regulation of dopaminergic neuron differentiation;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1905606//regulation of presynapse assembly;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:2000081//positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:2001141//regulation of RNA biosynthetic process"	--
ENSG00000154358	22.678	19.573	23.562	24.734	30.001	26.373	4993	4643	3860	3853	4949	4217	OBSCN	"obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [Source:HGNC Symbol;Acc:HGNC:15719]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030016//myofibril;GO:0030018//Z disc;GO:0031430//M band;GO:0042383//sarcolemma;GO:0043229//intracellular organelle	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0008307//structural constituent of muscle;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030506//ankyrin binding;GO:0031432//titin binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0106310//protein serine kinase activity"	GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0036309//protein localization to M-band;GO:0045214//sarcomere organization;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0098609//cell-cell adhesion	--
ENSG00000154359	2.54	2.307	2.19	4.258	3.909	3.018	165	161	96	156	152	130	LONRF1	LON peptidase N-terminal domain and ring finger 1 [Source:HGNC Symbol;Acc:HGNC:26302]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000154370	7.11	7.741	7.628	8.031	6.849	7.382	415	457	334	346	336	311	TRIM11	tripartite motif containing 11 [Source:HGNC Symbol;Acc:HGNC:16281]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046597//negative regulation of viral entry into host cell;GO:0046598//positive regulation of viral entry into host cell;GO:0050768//negative regulation of neurogenesis;GO:0051607//defense response to virus"	--
ENSG00000154380	17.912	15.181	16.42	7.114	12.26	9.572	1385	1152	656	494	637	492	ENAH	ENAH actin regulator [Source:HGNC Symbol;Acc:HGNC:18271]	Cellular Processes;Environmental Information Processing;Organismal Systems	Cell motility;Signal transduction;Development and regeneration	ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04360//Axon guidance	K05746;K05746;K05746	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0042995//cell projection;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0017124//SH3 domain binding;GO:0050699//WW domain binding	GO:0007411//axon guidance;GO:0008154//actin polymerization or depolymerization;GO:0070358//actin polymerization-dependent cell motility	--
ENSG00000154415	0	0	0	0	0	0	0	0	0	0	0	0	PPP1R3A	protein phosphatase 1 regulatory subunit 3A [Source:HGNC Symbol;Acc:HGNC:9291]	Organismal Systems;Human Diseases	Endocrine system;Endocrine and metabolic disease	ko04910//Insulin signaling pathway;ko04931//Insulin resistance	K07189;K07189	GO:0000164//protein phosphatase type 1 complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:2001069//glycogen binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process	--
ENSG00000154429	11.028	9.183	10.149	8.262	8.591	10.357	1165	956	794	646	768	788	CCSAP	"centriole, cilia and spindle associated protein [Source:HGNC Symbol;Acc:HGNC:29578]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030424//axon;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0061673//mitotic spindle astral microtubule;GO:0072686//mitotic spindle	GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0045995//regulation of embryonic development;GO:0051301//cell division;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:1901673//regulation of mitotic spindle assembly;GO:1990755//mitotic spindle microtubule depolymerization	--
ENSG00000154438	0	0	0	0	0.031	0	0	0	0	0	1	0	ASZ1	"ankyrin repeat, SAM and basic leucine zipper domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1350]"	-	-	-	-	GO:0005737//cytoplasm;GO:0071546//pi-body	GO:0005515//protein binding	GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000154447	5.604	5.372	4.101	3.761	4.024	3.753	577	525	318	290	348	290	SH3RF1	SH3 domain containing ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17650]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0001764//neuron migration;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043370//regulation of CD4-positive, alpha-beta T cell differentiation;GO:0046330//positive regulation of JNK cascade;GO:0051865//protein autoubiquitination;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000154451	0.014	0	0	0.028	0.036	0	2	0	0	2	3	0	GBP5	guanylate binding protein 5 [Source:HGNC Symbol;Acc:HGNC:19895]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20898	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0009617//response to bacterium;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032741//positive regulation of interleukin-18 production;GO:0034067//protein localization to Golgi apparatus;GO:0045089//positive regulation of innate immune response;GO:0051289//protein homotetramerization;GO:0071345//cellular response to cytokine stimulus;GO:0071346//cellular response to interferon-gamma;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly	--
ENSG00000154473	19.196	19.144	23.373	19.996	18.051	22.771	599	600	510	441	484	506	BUB3	BUB3 mitotic checkpoint protein [Source:HGNC Symbol;Acc:HGNC:1151]	Human Diseases;Cellular Processes	Infectious disease: viral;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04110//Cell cycle	K02180;K02180	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0033597//mitotic checkpoint complex;GO:1990298//bub1-bub3 complex"	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0034501//protein localization to kinetochore;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051983//regulation of chromosome segregation	--
ENSG00000154478	0.005	0.005	0.006	0	0.011	0	1	1	1	0	2	0	GPR26	G protein-coupled receptor 26 [Source:HGNC Symbol;Acc:HGNC:4481]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000154479	0.045	0.045	0.03	0.06	0.027	0.092	2	2	1	2	1	3	CFAP210	cilia and flagella associated protein 210 [Source:HGNC Symbol;Acc:HGNC:25064]	-	-	-	-	-	-	-	--
ENSG00000154485	0.259	0.025	0.043	0.119	0.155	0.329	9	1	1	3	5	9	MMP21	matrix metallopeptidase 21 [Source:HGNC Symbol;Acc:HGNC:14357]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006508//proteolysis;GO:0007368//determination of left/right symmetry;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0060976//coronary vasculature development;GO:0061371//determination of heart left/right asymmetry	--
ENSG00000154493	0.964	1.394	1.002	0.719	0.953	0.894	48	76	28	30	45	33	C10orf90	chromosome 10 open reading frame 90 [Source:HGNC Symbol;Acc:HGNC:26563]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton	GO:0008017//microtubule binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0046599//regulation of centriole replication;GO:0050821//protein stabilization	--
ENSG00000154511	91.654	88.129	81.334	54.247	60.747	68.497	4672	4536	3076	2080	2613	2570	DIPK1A	divergent protein kinase domain 1A [Source:HGNC Symbol;Acc:HGNC:32213]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000154518	86.371	79.094	89.637	101.209	88.867	98	2198	2054	1603	1837	1876	1807	ATP5MC3	ATP synthase membrane subunit c locus 3 [Source:HGNC Symbol;Acc:HGNC:843]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015078//proton transmembrane transporter activity	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:1902600//proton transmembrane transport	--
ENSG00000154529	2.024	1.374	0.837	1.124	1.901	1.725	135.02	87.34	68.31	53.37	100.14	87.59	CNTNAP3B	contactin associated protein family member 3B [Source:HGNC Symbol;Acc:HGNC:32035]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007155//cell adhesion	--
ENSG00000154545	15.312	3.852	3.834	8.744	10.571	17.595	776.24	204.41	114.54	340.47	470.42	661.55	MAGED4	MAGE family member D4 [Source:HGNC Symbol;Acc:HGNC:23793]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000154548	1.088	0.829	0.673	0.994	1.049	0.92	81	62	37	49	66	44	SRSF12	serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0050733//RS domain binding;GO:0051082//unfolded protein binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000154553	31.82	32.554	26.202	14.894	17.522	16.238	1643	1661	1031	481	735	590	PDLIM3	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding	GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0061061//muscle structure development	--
ENSG00000154556	80.79	77.972	78.399	58.489	67.792	66.455	3076	2924	2108	1800	2196	1670	SORBS2	sorbin and SH3 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24098]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0008307//structural constituent of muscle;GO:0042802//identical protein binding	GO:0007015//actin filament organization;GO:0007219//Notch signaling pathway;GO:0008150//biological_process;GO:0061049//cell growth involved in cardiac muscle cell development	--
ENSG00000154582	17.377	17.672	16.764	14.934	12.936	19.113	363	349	262	251	215	301	ELOC	elongin C [Source:HGNC Symbol;Acc:HGNC:11617]	Human Diseases;Human Diseases;Genetic Information Processing;Environmental Information Processing;Human Diseases	"Cancer: overview;Infectious disease: viral;Folding, sorting and degradation;Signal transduction;Cancer: specific types"	ko05200//Pathways in cancer;ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K03872;K03872;K03872;K03872;K03872	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0070449//elongin complex	GO:0001222//transcription corepressor binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006414//translational elongation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000154589	0.676	0.257	0	0.582	0.306	0.474	7	3	0	5	3	4	LY96	lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko04936//Alcoholic liver disease;ko05145//Toxoplasmosis;ko04620//Toll-like receptor signaling pathway;ko05133//Pertussis	K05400;K05400;K05400;K05400;K05400;K05400;K05400	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043235//receptor complex;GO:0046696//lipopolysaccharide receptor complex	GO:0001530//lipopolysaccharide binding;GO:0001875//lipopolysaccharide immune receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0035662//Toll-like receptor 4 binding	GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007166//cell surface receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032497//detection of lipopolysaccharide;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000154611	0	0	0	0	0	0	0	0	0	0	0	0	PSMA8	proteasome 20S subunit alpha 8 [Source:HGNC Symbol;Acc:HGNC:22985]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02731;K02731;K02731;K02731;K02731;K02731;K02731;K02731	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular exosome;GO:1990111//spermatoproteasome complex"	-	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0007283//spermatogenesis;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0030154//cell differentiation;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051321//meiotic cell cycle;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060631//regulation of meiosis I;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000154620	0.108	0.323	0.146	0.195	0.213	0.099	3	9	3	4	5	2	TMSB4Y	thymosin beta 4 Y-linked [Source:HGNC Symbol;Acc:HGNC:11882]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05764	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0008064//regulation of actin polymerization or depolymerization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers	--
ENSG00000154639	21.612	17.468	19.004	15.229	15.366	19.245	1900	1568	1185	893	1093	1238	CXADR	CXADR Ig-like cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:2559]	Human Diseases	Cardiovascular disease	ko05416//Viral myocarditis	K06788	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030426//growth cone;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045121//membrane raft	GO:0001618//virus receptor activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0071253//connexin binding;GO:0086082//cell adhesive protein binding involved in AV node cell-bundle of His cell communication	GO:0007005//mitochondrion organization;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007507//heart development;GO:0008354//germ cell migration;GO:0010669//epithelial structure maintenance;GO:0030593//neutrophil chemotaxis;GO:0031532//actin cytoskeleton reorganization;GO:0034109//homotypic cell-cell adhesion;GO:0045216//cell-cell junction organization;GO:0046629//gamma-delta T cell activation;GO:0046718//viral entry into host cell;GO:0051607//defense response to virus;GO:0055013//cardiac muscle cell development;GO:0070633//transepithelial transport;GO:0086067//AV node cell to bundle of His cell communication;GO:0086072//AV node cell-bundle of His cell adhesion involved in cell communication;GO:0098904//regulation of AV node cell action potential	--
ENSG00000154640	18.109	15.386	17.538	11.834	10.778	14.118	513	449	376	257	259	301	BTG3	BTG anti-proliferation factor 3 [Source:HGNC Symbol;Acc:HGNC:1132]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0008285//negative regulation of cell population proliferation;GO:0045930//negative regulation of mitotic cell cycle	--
ENSG00000154642	6.142	4.507	4.658	4.802	3.91	4.93	502	396	291	259	289	316	C21orf91	chromosome 21 open reading frame 91 [Source:HGNC Symbol;Acc:HGNC:16459]	-	-	-	-	-	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0021895//cerebral cortex neuron differentiation;GO:0030154//cell differentiation;GO:0060999//positive regulation of dendritic spine development	--
ENSG00000154645	0.52	0.464	0.279	0.335	0.382	0.305	25	20	7	11	15	8	CHODL	chondrolectin [Source:HGNC Symbol;Acc:HGNC:17807]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007399//nervous system development;GO:0007517//muscle organ development;GO:0010975//regulation of neuron projection development;GO:0050772//positive regulation of axonogenesis	--
ENSG00000154646	0.024	0.035	0.016	0.016	0.056	0	2	3	1	1	4	0	TMPRSS15	transmembrane serine protease 15 [Source:HGNC Symbol;Acc:HGNC:9490]	-	-	-	-	GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006897//endocytosis	--
ENSG00000154654	3.859	3.128	3.035	2.588	3.17	2.923	422	326	241	200	275	227	NCAM2	neural cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:7657]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signaling molecules and interaction	ko05020//Prion disease;ko04514//Cell adhesion molecules	K06491;K06491	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0030424//axon;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007413//axonal fasciculation;GO:0007608//sensory perception of smell	--
ENSG00000154655	2.355	2.489	1.625	2.488	2.326	2.016	175	187	89	136	146	109	L3MBTL4	L3MBTL histone methyl-lysine binding protein 4 [Source:HGNC Symbol;Acc:HGNC:26677]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2HC
ENSG00000154678	0.597	0.513	0.258	0.429	0.389	0.199	78	55	26	27	43	21	PDE1C	phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Sensory system;Signal transduction;Nucleotide metabolism;Substance dependence;Sensory system;Endocrine system	ko01100//Metabolic pathways;ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04742//Taste transduction;ko04924//Renin secretion	K13755;K13755;K13755;K13755;K13755;K13755;K13755	GO:0005829//cytosol;GO:0043025//neuronal cell body	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0005516//calmodulin binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0048101//calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction	--
ENSG00000154710	10.024	7.881	8.479	8.64	7.962	9.667	616.73	514.91	402.99	428	417.15	421.46	RABGEF1	RAB guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:17676]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0030139//endocytic vesicle;GO:0031901//early endosome membrane;GO:0055037//recycling endosome	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0006612//protein targeting to membrane;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016567//protein ubiquitination;GO:0050790//regulation of catalytic activity	--
ENSG00000154719	5.727	6.621	5.925	6.109	6.957	5.749	129	150	98	102	132	94	MRPL39	mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:14027]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000154721	1.467	1.914	1.144	0.619	1.028	0.795	132	127	72	32	59	43	JAM2	junctional adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:14686]	Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Cellular community - eukaryotes;Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04530//Tight junction;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K06735;K06735;K06735;K06735	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0036477//somatodendritic compartment;GO:0044291//cell-cell contact zone;GO:0070160//tight junction;GO:0098636//protein complex involved in cell adhesion	GO:0005178//integrin binding;GO:0005515//protein binding	GO:0007286//spermatid development;GO:0007520//myoblast fusion;GO:0031642//negative regulation of myelination;GO:0035633//maintenance of blood-brain barrier;GO:0045123//cellular extravasation;GO:0050901//leukocyte tethering or rolling;GO:0071593//lymphocyte aggregation;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0098609//cell-cell adhesion;GO:2000403//positive regulation of lymphocyte migration	--
ENSG00000154723	83.514	81.09	77.999	99.787	75.427	97.236	996.39	974.08	677.25	869.13	750.82	836.08	ATP5PF	ATP synthase peripheral stalk subunit F6 [Source:HGNC Symbol;Acc:HGNC:847]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02131;K02131;K02131;K02131;K02131;K02131;K02131;K02131;K02131;K02131;K02131	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0021762//substantia nigra development;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000154727	7.274	5.445	5.218	3.671	4.315	5.272	785.61	589.92	417.75	293.87	395.18	414.92	GABPA	GA binding protein transcription factor subunit alpha [Source:HGNC Symbol;Acc:HGNC:4071]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001825//blastocyst formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903351//cellular response to dopamine"	ETS
ENSG00000154734	32.093	31.069	30.355	19.882	19.539	24.287	2982	2907	2066	1395	1529	1571	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0031012//extracellular matrix;GO:0031410//cytoplasmic vesicle;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001542//ovulation from ovarian follicle;GO:0001822//kidney development;GO:0006508//proteolysis;GO:0007229//integrin-mediated signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0016525//negative regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0060347//heart trabecula formation;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration	--
ENSG00000154736	3.984	3.272	2.063	2.195	2.783	2.721	691	538	279	283	445	349	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif 5 [Source:HGNC Symbol;Acc:HGNC:221]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0006508//proteolysis;GO:0007520//myoblast fusion;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0042742//defense response to bacterium;GO:0044691//tooth eruption;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000154743	4.612	4.469	4.617	5.489	5.184	5.352	214	202	155	179	194	172	TSEN2	tRNA splicing endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:28422]	-	-	-	-	GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005829//cytosol	GO:0000213//tRNA-intron endonuclease activity;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016829//lyase activity	"GO:0000379//tRNA-type intron splice site recognition and cleavage;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0008033//tRNA processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000154760	0.535	0.586	0.633	0.443	0.71	0.42	51.19	51	35.75	22	27.08	25.81	SLFN13	schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481]	-	-	-	-	GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0016075//rRNA catabolic process;GO:0016078//tRNA catabolic process;GO:0051607//defense response to virus;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000154764	0	0	0	0	0	0	0	0	0	0	0	0	WNT7A	Wnt family member 7A [Source:HGNC Symbol;Acc:HGNC:12786]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity	"GO:0000578//embryonic axis specification;GO:0001502//cartilage condensation;GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0007269//neurotransmitter secretion;GO:0007275//multicellular organism development;GO:0007409//axonogenesis;GO:0007548//sex differentiation;GO:0008284//positive regulation of cell population proliferation;GO:0009953//dorsal/ventral pattern formation;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0014719//skeletal muscle satellite cell activation;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0016055//Wnt signaling pathway;GO:0021707//cerebellar granule cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0022009//central nervous system vasculogenesis;GO:0030010//establishment of cell polarity;GO:0030182//neuron differentiation;GO:0030326//embryonic limb morphogenesis;GO:0031133//regulation of axon diameter;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032355//response to estradiol;GO:0035019//somatic stem cell population maintenance;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035313//wound healing, spreading of epidermal cells;GO:0035567//non-canonical Wnt signaling pathway;GO:0036465//synaptic vesicle recycling;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043627//response to estrogen;GO:0045165//cell fate commitment;GO:0045167//asymmetric protein localization involved in cell fate determination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048103//somatic stem cell division;GO:0048864//stem cell development;GO:0050768//negative regulation of neurogenesis;GO:0050770//regulation of axonogenesis;GO:0050808//synapse organization;GO:0051216//cartilage development;GO:0051965//positive regulation of synapse assembly;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060065//uterus development;GO:0060066//oviduct development;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060173//limb development;GO:0060997//dendritic spine morphogenesis;GO:0061038//uterus morphogenesis;GO:0062009//secondary palate development;GO:0070307//lens fiber cell development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0099054//presynapse assembly;GO:0099068//postsynapse assembly;GO:0099175//regulation of postsynapse organization;GO:1904861//excitatory synapse assembly;GO:1904891//positive regulation of excitatory synapse assembly;GO:1905386//positive regulation of protein localization to presynapse;GO:1905606//regulation of presynapse assembly;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000154767	7.252	7.858	7.833	6.767	7.786	7.967	549	598	438	365	498	438.87	XPC	"XPC complex subunit, DNA damage recognition and repair factor [Source:HGNC Symbol;Acc:HGNC:12816]"	Genetic Information Processing	Replication and repair	ko03420//Nucleotide excision repair	K10838	GO:0000109//nucleotide-excision repair complex;GO:0000111//nucleotide-excision repair factor 2 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071942//XPC complex;GO:0090734//site of DNA damage	GO:0000404//heteroduplex DNA loop binding;GO:0000405//bubble DNA binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0140612//DNA damage sensor activity	"GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0010224//response to UV-B;GO:0010996//response to auditory stimulus;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070914//UV-damage excision repair;GO:1901990//regulation of mitotic cell cycle phase transition;GO:1990731//UV-damage excision repair, DNA incision"	--
ENSG00000154781	5.575	5.172	5.173	4.228	5.318	5.793	340	317	233	191	274	257	CCDC174	coiled-coil domain containing 174 [Source:HGNC Symbol;Acc:HGNC:28033]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000154783	0	0	0	0	0.044	0	0	0	0	0	3	0	FGD5	"FYVE, RhoGEF and PH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19117]"	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000154803	10.505	11.154	11.998	11.555	10.354	11.751	757.35	806.04	612.78	564.89	609.28	596.02	FLCN	folliculin [Source:HGNC Symbol;Acc:HGNC:27310]	Environmental Information Processing;Human Diseases	Signal transduction;Cancer: specific types	ko04150//mTOR signaling pathway;ko05211//Renal cell carcinoma	K09594;K09594	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0030496//midbody;GO:0042995//cell projection;GO:0044291//cell-cell contact zone;GO:0072686//mitotic spindle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0007043//cell-cell junction assembly;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0010508//positive regulation of autophagy;GO:0010629//negative regulation of gene expression;GO:0010823//negative regulation of mitochondrion organization;GO:0030097//hemopoiesis;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031929//TOR signaling;GO:0032006//regulation of TOR signaling;GO:0032007//negative regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0032418//lysosome localization;GO:0032465//regulation of cytokinesis;GO:0034198//cellular response to amino acid starvation;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035065//regulation of histone acetylation;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045785//positive regulation of cell adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046578//regulation of Ras protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051898//negative regulation of protein kinase B signaling;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0097009//energy homeostasis;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900181//negative regulation of protein localization to nucleus;GO:1901723//negative regulation of cell proliferation involved in kidney development;GO:1901856//negative regulation of cellular respiration;GO:1901859//negative regulation of mitochondrial DNA metabolic process;GO:1901862//negative regulation of muscle tissue development;GO:1901874//negative regulation of post-translational protein modification;GO:1903444//negative regulation of brown fat cell differentiation;GO:1904263//positive regulation of TORC1 signaling;GO:2000973//regulation of pro-B cell differentiation;GO:2001170//negative regulation of ATP biosynthetic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000154813	10.828	8.338	9.293	8.467	7.454	8.959	747	577	480	421	440	443	DPH3	diphthamide biosynthesis 3 [Source:HGNC Symbol;Acc:HGNC:27717]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002098//tRNA wobble uridine modification;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0050709//negative regulation of protein secretion;GO:0051099//positive regulation of binding	--
ENSG00000154814	4.043	4.727	4.654	2.908	4.682	5.951	205	204	166	104	162	197	OXNAD1	oxidoreductase NAD binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25128]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0008150//biological_process	--
ENSG00000154822	3.789	2.778	2.696	1.508	1.797	2.102	327	241	171	95	131	132	PLCL2	phospholipase C like 2 [Source:HGNC Symbol;Acc:HGNC:9064]	-	-	-	-	GO:0005737//cytoplasm	"GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0050811//GABA receptor binding;GO:0070679//inositol 1,4,5 trisphosphate binding"	"GO:0002322//B cell proliferation involved in immune response;GO:0002337//B-1a B cell differentiation;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0016042//lipid catabolic process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900122//positive regulation of receptor binding"	--
ENSG00000154832	13.016	12.283	13.276	14.943	16.009	15.803	627	582	472	497	643	554	CXXC1	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0035097//histone methyltransferase complex;GO:0048188//Set1C/COMPASS complex	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051568//histone H3-K4 methylation"	--
ENSG00000154839	0.458	0.437	0.346	0.192	0.218	0.233	8	11	8	6	9	10	SKA1	spindle and kinetochore associated complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28109]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0034451//centriolar satellite;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle"	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division	--
ENSG00000154845	22.904	21.821	24.824	20.886	17.086	23.901	1533	1525	1209	1039	1139	1123	PPP4R1	protein phosphatase 4 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:9320]	-	-	-	-	GO:0030289//protein phosphatase 4 complex	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000154856	6.974	3.377	6.762	6.913	3.331	4.579	236	216	247	180	222	225	APCDD1	APC down-regulated 1 [Source:HGNC Symbol;Acc:HGNC:15718]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0042802//identical protein binding	GO:0001942//hair follicle development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0043615//astrocyte cell migration	--
ENSG00000154864	4.738	3.651	3.505	2.654	3.81	4.455	790	669	460	375	583	521	PIEZO2	piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005261//cation channel activity;GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0009612//response to mechanical stimulus;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050896//response to stimulus;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0050982//detection of mechanical stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0098655//cation transmembrane transport	--
ENSG00000154889	15.988	11.266	12.434	13.609	14.233	9.699	348.22	391.09	278.87	256.8	332.2	244.12	MPPE1	metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K23362;K23362	GO:0005654//nucleoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0070971//endoplasmic reticulum exit site	GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0034235//GPI anchor binding;GO:0046872//metal ion binding;GO:0062050//GPI-mannose ethanolamine phosphate phosphodiesterase activity	GO:0006506//GPI anchor biosynthetic process;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport	--
ENSG00000154914	0.66	0.721	0.81	0.949	1.145	1.128	47	59	50	61	84	68	USP43	ubiquitin specific peptidase 43 [Source:HGNC Symbol;Acc:HGNC:20072]	-	-	-	-	GO:0005654//nucleoplasm	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019785//ISG15-specific protease activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0019985//translesion synthesis	--
ENSG00000154917	23.443	22.147	25.792	30.646	26.027	29.905	1814	1903.94	1596.89	1362.98	1652.9	1727	RAB6B	"RAB6B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14902]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031489//myosin V binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000154920	0.684	0.426	1.068	0.476	0.5	0.428	33.04	18.02	32	17.03	16	15.06	EME1	essential meiotic structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:24965]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K10882;K10882	GO:0000785//chromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043596//nuclear replication fork;GO:0048476//Holliday junction resolvase complex;GO:1905347//endodeoxyribonuclease complex	GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0072429//response to intra-S DNA damage checkpoint signaling;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000154928	1.527	1.382	1.955	1.309	1.074	1.219	148	133	140	94	88	86	EPHB1	EPH receptor B1 [Source:HGNC Symbol;Acc:HGNC:3392]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05110	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031901//early endosome membrane;GO:0032433//filopodium tip;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0044877//protein-containing complex binding	GO:0001525//angiogenesis;GO:0001771//immunological synapse formation;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0014719//skeletal muscle satellite cell activation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021545//cranial nerve development;GO:0021631//optic nerve morphogenesis;GO:0021934//hindbrain tangential cell migration;GO:0021952//central nervous system projection neuron axonogenesis;GO:0022008//neurogenesis;GO:0030010//establishment of cell polarity;GO:0031290//retinal ganglion cell axon guidance;GO:0031589//cell-substrate adhesion;GO:0033674//positive regulation of kinase activity;GO:0046328//regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0048593//camera-type eye morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051965//positive regulation of synapse assembly;GO:0060326//cell chemotaxis;GO:0060996//dendritic spine development;GO:0060997//dendritic spine morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:1901214//regulation of neuron death;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation;GO:1902725//negative regulation of satellite cell differentiation	--
ENSG00000154930	12.18	12.107	16.618	17.687	16.539	18.256	902	907	910	979	1029	981	ACSS1	acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K01895;K01895;K01895;K01895;K01895;K01895	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0003987//acetate-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016874//ligase activity;GO:0050218//propionate-CoA ligase activity	GO:0006069//ethanol oxidation;GO:0006085//acetyl-CoA biosynthetic process;GO:0006629//lipid metabolic process;GO:0019413//acetate biosynthetic process;GO:0019427//acetyl-CoA biosynthetic process from acetate;GO:0019542//propionate biosynthetic process	--
ENSG00000154945	9.803	8.359	10.242	9.693	9.971	9.575	834	726	643	612	705	602	ANKRD40	ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000154957	3.088	3.921	4.179	2.729	3.095	2.641	146	188	147	97	126	91	ZNF18	zinc finger protein 18 [Source:HGNC Symbol;Acc:HGNC:12969]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000154975	0.133	0.246	0.219	0.35	0.349	0.195	8	12	6	14	14	6	CA10	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC:1369]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016836//hydro-lyase activity	GO:0006730//one-carbon metabolic process;GO:0007420//brain development	--
ENSG00000154978	45.1	50.306	43.662	47.231	46.333	44.077	2699	2904	1925	2015	2346	1909	VOPP1	VOPP1 WW domain binding protein [Source:HGNC Symbol;Acc:HGNC:34518]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031301//integral component of organelle membrane;GO:0031410//cytoplasmic vesicle	-	-	--
ENSG00000154997	0.039	0	0.052	0	0	0	3	0	3	0	0	0	SEPTIN14	septin 14 [Source:HGNC Symbol;Acc:HGNC:33280]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0030424//axon;GO:0030425//dendrite;GO:0031105//septin complex;GO:0031410//cytoplasmic vesicle;GO:0032153//cell division site;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0060090//molecular adaptor activity	GO:0001764//neuron migration;GO:0007049//cell cycle;GO:0007286//spermatid development;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000155008	4.992	4.056	3.667	3.194	3.355	3.794	670.99	548	363.98	317.99	381	371	APOOL	apolipoprotein O like [Source:HGNC Symbol;Acc:HGNC:24009]	-	-	-	-	GO:0001401//SAM complex;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031093//platelet alpha granule lumen;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation	--
ENSG00000155011	0	0.052	0.018	0	0	0	0	1	1	0	0	0	DKK2	dickkopf WNT signaling pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:2892]	Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway	K02165;K02165;K02165	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0039706//co-receptor binding;GO:0048019//receptor antagonist activity	GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000155016	12.386	13.007	12.842	12.877	12.311	12.98	1219	1293	938	908	1019	934	CYP2U1	cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00071//Fatty acid degradation	K07422;K07422;K07422	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0052869//arachidonic acid omega-hydroxylase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000155026	0.113	0.092	0.217	0	0	0	6.85	5.6	9.64	0	0	0	RSPH10B	radial spoke head 10 homolog B [Source:HGNC Symbol;Acc:HGNC:27362]	-	-	-	-	-	-	-	--
ENSG00000155034	4.15	4.463	5.052	4.234	4.672	4.767	702	764.28	632	538	655	587	FBXL18	F-box and leucine rich repeat protein 18 [Source:HGNC Symbol;Acc:HGNC:21874]	-	-	-	-	GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000155052	0.348	0.329	0.447	0.354	0.413	0.337	81	69	67	61	72	57	CNTNAP5	contactin associated protein family member 5 [Source:HGNC Symbol;Acc:HGNC:18748]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007155//cell adhesion	--
ENSG00000155066	0.038	0	0.017	0.022	0.133	0.053	3	0	1	1	11	3	PROM2	prominin 2 [Source:HGNC Symbol;Acc:HGNC:20685]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031528//microvillus membrane;GO:0042995//cell projection;GO:0044393//microspike;GO:0045121//membrane raft;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0071914//prominosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015485//cholesterol binding	GO:0001934//positive regulation of protein phosphorylation;GO:0031346//positive regulation of cell projection organization;GO:0043087//regulation of GTPase activity;GO:0048550//negative regulation of pinocytosis;GO:2001287//negative regulation of caveolin-mediated endocytosis	--
ENSG00000155085	3.495	2.903	1.913	1.853	1.345	2.376	144	133	74	72	63	88	AK9	adenylate kinase 9 [Source:HGNC Symbol;Acc:HGNC:33814]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K18533;K18533;K18533	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031965//nuclear membrane	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0050145//nucleoside monophosphate kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006174//dADP phosphorylation;GO:0006186//dGDP phosphorylation;GO:0006756//AMP phosphorylation;GO:0006757//ATP generation from ADP;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation;GO:0061508//CDP phosphorylation;GO:0061565//dAMP phosphorylation;GO:0061566//CMP phosphorylation;GO:0061567//dCMP phosphorylation;GO:0061568//GDP phosphorylation;GO:0061569//UDP phosphorylation;GO:0061570//dCDP phosphorylation;GO:0061571//TDP phosphorylation	--
ENSG00000155087	0	0	0	0	0	0	0	0	0	0	0	0	ODF1	outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113]	-	-	-	-	GO:0001520//outer dense fiber;GO:0005634//nucleus	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000155090	8.242	9.655	8.81	6.48	6.995	6.55	505	591	398	299	365	296	KLF10	Kruppel like factor 10 [Source:HGNC Symbol;Acc:HGNC:11810]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001046//core promoter sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0007623//circadian rhythm;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0030282//bone mineralization;GO:0035019//somatic stem cell population maintenance;GO:0042752//regulation of circadian rhythm;GO:0045672//positive regulation of osteoclast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	zf-C2H2
ENSG00000155093	1.623	2.093	2.017	2.089	2.007	1.856	158	205	145	138	165	133	PTPRN2	protein tyrosine phosphatase receptor type N2 [Source:HGNC Symbol;Acc:HGNC:9677]	Human Diseases	Endocrine and metabolic disease	ko04940//Type I diabetes mellitus	K07817	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043235//receptor complex;GO:0045202//synapse;GO:0101003//ficolin-1-rich granule membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0007269//neurotransmitter secretion;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035773//insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000155096	39.543	39.041	40.788	35.302	34.079	40.312	2980	2951	2252	2042	2223	2170	AZIN1	antizyme inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:16432]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004586//ornithine decarboxylase activity;GO:0005515//protein binding;GO:0042978//ornithine decarboxylase activator activity	GO:0006596//polyamine biosynthetic process;GO:0033387//putrescine biosynthetic process from ornithine;GO:0042177//negative regulation of protein catabolic process;GO:0050790//regulation of catalytic activity;GO:1902269//positive regulation of polyamine transmembrane transport	--
ENSG00000155097	28.817	25.826	24.258	19.805	20.946	29.368	1765	1508	1099	957	1080	1271	ATP6V1C1	ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148;K02148	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0031410//cytoplasmic vesicle;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0045177//apical part of cell;GO:0070062//extracellular exosome"	"GO:0005215//transporter activity;GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0016241//regulation of macroautophagy;GO:1902600//proton transmembrane transport	--
ENSG00000155099	20.001	15.758	20.108	19.159	17.658	27.245	617	520	476	500	477	630	PIP4P2	"phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:25452]"	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K13084	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity"	GO:0006629//lipid metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0050765//negative regulation of phagocytosis	--
ENSG00000155100	3.582	3.049	2.938	2.779	2.705	3.341	219	189	148	122	150	160	OTUD6B	OTU deubiquitinase 6B [Source:HGNC Symbol;Acc:HGNC:24281]	-	-	-	-	GO:0016281//eukaryotic translation initiation factor 4F complex	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0008283//cell population proliferation;GO:0016579//protein deubiquitination;GO:0017148//negative regulation of translation;GO:0043248//proteasome assembly;GO:0045727//positive regulation of translation	--
ENSG00000155111	6.162	5.478	4.948	4.132	5.681	4.669	761	583	470	384	485	437	CDK19	cyclin dependent kinase 19 [Source:HGNC Symbol;Acc:HGNC:19338]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016592//mediator complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0050729//positive regulation of inflammatory response;GO:0051726//regulation of cell cycle;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000155115	25.635	22.887	26.674	24.449	21.58	27.496	419	376	322	296	298	327	GTF3C6	general transcription factor IIIC subunit 6 [Source:HGNC Symbol;Acc:HGNC:20872]	-	-	-	-	GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006383//transcription by RNA polymerase III;GO:0042791//5S class rRNA transcription by RNA polymerase III;GO:0042797//tRNA transcription by RNA polymerase III	--
ENSG00000155158	1.078	0.803	1.396	1.036	0.457	0.795	127	80	80	67	51	82	TTC39B	tetratricopeptide repeat domain 39B [Source:HGNC Symbol;Acc:HGNC:23704]	-	-	-	-	-	GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0010874//regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0042632//cholesterol homeostasis;GO:0090181//regulation of cholesterol metabolic process	--
ENSG00000155189	11.152	10.367	9.806	6.819	8.687	8.298	935	810	573	469	569	522	AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:20886]	Metabolism;Environmental Information Processing;Metabolism;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K19007;K19007;K19007;K19007	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006629//lipid metabolic process;GO:0006639//acylglycerol metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process	--
ENSG00000155229	40.404	55.396	52.6	63.565	59.866	62.798	2652	2907	2408	2692	2808	2680	MMS19	"MMS19 homolog, cytosolic iron-sulfur assembly component [Source:HGNC Symbol;Acc:HGNC:13824]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005675//transcription factor TFIIH holo complex;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0071817//MMXD complex;GO:0097361//CIA complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030331//estrogen receptor binding;GO:0030674//protein-macromolecule adaptor activity	"GO:0000160//phosphorelay signal transduction system;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007059//chromosome segregation;GO:0009725//response to hormone;GO:0016226//iron-sulfur cluster assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:1905168//positive regulation of double-strand break repair via homologous recombination"	--
ENSG00000155249	0	0	0	0	0	0	0	0	0	0	0	0	OR4K1	olfactory receptor family 4 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:14726]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000155252	33.668	34.416	35.621	35.018	37.19	35.738	2925.36	3005.73	2285.87	2253.78	2730	2259.35	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha [Source:HGNC Symbol;Acc:HGNC:30031]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K13711;K13711;K13711	GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031083//BLOC-1 complex;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0035838//growing cell tip;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035651//AP-3 adaptor complex binding	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007030//Golgi organization;GO:0007032//endosome organization;GO:0016310//phosphorylation;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000155254	46.636	53.294	53.798	64.337	62.73	57.042	3108	3570	2648	3176	3532	2766	MARVELD1	MARVEL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28674]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0019911//structural constituent of myelin sheath	GO:0007049//cell cycle;GO:0042552//myelination	--
ENSG00000155256	14.057	13.848	17.176	18.641	17.422	21.68	860	850	762	847	889	956	ZFYVE27	zinc finger FYVE-type containing 27 [Source:HGNC Symbol;Acc:HGNC:26559]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K19368	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032584//growth cone membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0046872//metal ion binding	GO:0016192//vesicle-mediated transport;GO:0031175//neuron projection development;GO:0045773//positive regulation of axon extension;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071787//endoplasmic reticulum tubular network formation;GO:0072659//protein localization to plasma membrane	--
ENSG00000155265	1.824	1.539	2.051	2.026	1.496	1.97	246	217	208	209	171	203	GOLGA7B	golgin A7 family member B [Source:HGNC Symbol;Acc:HGNC:31668]	-	-	-	-	GO:0000139//Golgi membrane;GO:0002178//palmitoyltransferase complex;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation	--
ENSG00000155269	0.041	0.096	0.015	0.149	0.096	0.107	4.23	9.92	1	11.35	8.32	7.7	GPR78	G protein-coupled receptor 78 [Source:HGNC Symbol;Acc:HGNC:4528]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000155275	3.028	3.221	3.975	3.641	3.163	2.513	170	193	175	138	154	109	TRMT44	tRNA methyltransferase 44 homolog [Source:HGNC Symbol;Acc:HGNC:26653]	-	-	-	-	GO:0005737//cytoplasm	GO:0008168//methyltransferase activity;GO:0016300//tRNA (uracil) methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0052665//tRNA (uracil-2'-O-)-methyltransferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000155287	9.192	8.755	9.189	10.213	9.199	6.543	271	251	190	210	234	150	SLC25A28	solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005381//iron ion transmembrane transporter activity	GO:0006811//ion transport;GO:0048250//iron import into the mitochondrion;GO:0055072//iron ion homeostasis	--
ENSG00000155304	22.291	19.478	18.714	16.399	16.215	17.955	1824	1602	1131	994	1121	1069	HSPA13	heat shock protein family A (Hsp70) member 13 [Source:HGNC Symbol;Acc:HGNC:11375]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031072//heat shock protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000155307	0	0.052	0	0	0.061	0	0	2	0	0	2	0	SAMSN1	"SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528]"	-	-	-	-	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042995//cell projection;GO:0110165//cellular anatomical entity	GO:0001784//phosphotyrosine residue binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0002820//negative regulation of adaptive immune response;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050869//negative regulation of B cell activation	--
ENSG00000155313	12.49	10.857	10.328	7.925	6.554	8.498	913	760	473	424	472	529	USP25	ubiquitin specific peptidase 25 [Source:HGNC Symbol;Acc:HGNC:12624]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K11849	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0031625//ubiquitin protein ligase binding;GO:0032183//SUMO binding;GO:0043130//ubiquitin binding;GO:0051117//ATPase binding	GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1904293//negative regulation of ERAD pathway	--
ENSG00000155324	27.579	26.321	28.823	23.285	29.938	28.679	1534	1348	1110	897	1217	1060	GRAMD2B	GRAM domain containing 2B [Source:HGNC Symbol;Acc:HGNC:24911]	-	-	-	-	GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000155329	4.804	3.568	3.917	3.201	3.535	3.549	166	107	91	62	67	82	ZCCHC10	zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000155330	3.1	2.61	3.036	2.562	2.389	2.822	439	365	316	268	285	290	C16orf87	chromosome 16 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:33754]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000155363	11.557	11.585	13.986	12.886	13.765	11.187	825	823	737	678	827	588	MOV10	Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200]	-	-	-	-	GO:0000932//P-body;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043186//P granule	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0032574//5'-3' RNA helicase activity	"GO:0010526//negative regulation of transposition, RNA-mediated;GO:0031047//gene silencing by RNA;GO:0035194//post-transcriptional gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0035279//mRNA cleavage involved in gene silencing by miRNA;GO:0051607//defense response to virus;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0150011//regulation of neuron projection arborization"	--
ENSG00000155366	102.387	105.99	101.881	96.147	88.4	88.583	2247	2370	1687	1645	1690	1472	RHOC	ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Cancer: overview;Signal transduction;Signal transduction;Endocrine system;Cardiovascular disease;Circulatory system;Immune system;Nervous system;Signal transduction;Immune system;Immune system;Immune system;Endocrine system;Digestive system;Signal transduction;Cancer: specific types;Infectious disease: bacterial;Infectious disease: bacterial;Cellular community - eukaryotes;Development and regeneration	"ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05100//Bacterial invasion of epithelial cells;ko05133//Pertussis;ko04520//Adherens junction;ko04361//Axon regeneration"	K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513;K04513	GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	"GO:0000281//mitotic cytokinesis;GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0030865//cortical cytoskeleton organization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032956//regulation of actin cytoskeleton organization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043297//apical junction assembly;GO:0044319//wound healing, spreading of cells;GO:0051496//positive regulation of stress fiber assembly;GO:0060193//positive regulation of lipase activity;GO:1902766//skeletal muscle satellite cell migration"	--
ENSG00000155367	0.422	0.224	0.038	0.418	0.581	0.232	15	8	1	11	19	6	PPM1J	"protein phosphatase, Mg2+/Mn2+ dependent 1J [Source:HGNC Symbol;Acc:HGNC:20785]"	-	-	-	-	-	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000155368	167.618	159.506	195.969	184.589	140.832	220.344	1963	1877	1694	1600	1393	1876	DBI	"diazepam binding inhibitor, acyl-CoA binding protein [Source:HGNC Symbol;Acc:HGNC:2690]"	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K08762	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0032994//protein-lipid complex;GO:0070062//extracellular exosome	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030156//benzodiazepine receptor binding;GO:0036042//long-chain fatty acyl-CoA binding;GO:0042802//identical protein binding	GO:0006631//fatty acid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:1903060//negative regulation of protein lipidation;GO:1905920//positive regulation of CoA-transferase activity;GO:2001140//positive regulation of phospholipid transport	--
ENSG00000155380	139.107	138.298	116.985	91.878	112.037	104.82	10837	10830	6730	5305	7371	5939	SLC16A1	solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922]	-	-	-	-	GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015130//mevalonate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0097159//organic cyclic compound binding	GO:0006629//lipid metabolic process;GO:0007098//centrosome cycle;GO:0015718//monocarboxylic acid transport;GO:0015728//mevalonate transport;GO:0032094//response to food;GO:0035873//lactate transmembrane transport;GO:0035879//plasma membrane lactate transport;GO:0042593//glucose homeostasis;GO:0050796//regulation of insulin secretion;GO:0051780//behavioral response to nutrient;GO:0055085//transmembrane transport;GO:0071407//cellular response to organic cyclic compound;GO:0150104//transport across blood-brain barrier;GO:1905039//carboxylic acid transmembrane transport	--
ENSG00000155393	4.777	4.798	4.749	4.102	4.004	4.268	291	272	206	181	212	188	HEATR3	HEAT repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:26087]	-	-	-	-	-	GO:0051082//unfolded protein binding	GO:0006606//protein import into nucleus;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000155428	0	0.049	0.079	0.147	0.228	0.11	0	1.31	1.63	3.05	5.31	2.19	TRIM74	tripartite motif containing 74 [Source:HGNC Symbol;Acc:HGNC:17453]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000155438	13.776	12.2	14.615	14.246	10.048	9.508	390	373	297	265	275	222	NIFK	nucleolar protein interacting with the FHA domain of MKI67 [Source:HGNC Symbol;Acc:HGNC:17838]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0009303//rRNA transcription;GO:0016072//rRNA metabolic process;GO:0065003//protein-containing complex assembly"	--
ENSG00000155463	71.162	73.133	71.66	81.671	73.593	78.063	2565	2643	1904	2170	2230	2039	OXA1L	OXA1L mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03217	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane;GO:0032592//integral component of mitochondrial membrane;GO:0032991//protein-containing complex;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0032977//membrane insertase activity;GO:0042803//protein homodimerization activity;GO:0097177//mitochondrial ribosome binding	GO:0009060//aerobic respiration;GO:0032780//negative regulation of ATPase activity;GO:0032979//protein insertion into mitochondrial inner membrane from matrix;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0051205//protein insertion into membrane;GO:0051262//protein tetramerization;GO:0051354//negative regulation of oxidoreductase activity;GO:0090150//establishment of protein localization to membrane	--
ENSG00000155465	8.308	9.665	4.158	37.364	31.608	27.66	335	371	111	970	1006	806	SLC7A7	solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K13867	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0015174//basic amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0000821//regulation of arginine metabolic process;GO:0006865//amino acid transport;GO:0015807//L-amino acid transport;GO:0055085//transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1990822//basic amino acid transmembrane transport	--
ENSG00000155495	0	0	0	0	0	0	0	0	0	0	0	0	MAGEC1	MAGE family member C1 [Source:HGNC Symbol;Acc:HGNC:6812]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000155506	38.408	36.599	41.16	35.448	44.268	43.123	5049	4916	3836	3415	4377	3869	LARP1	"La ribonucleoprotein 1, translational regulator [Source:HGNC Symbol;Acc:HGNC:29531]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0031931//TORC1 complex;GO:0042788//polysomal ribosome	GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0008494//translation activator activity;GO:0031369//translation initiation factor binding;GO:0043024//ribosomal small subunit binding;GO:0045296//cadherin binding;GO:0048027//mRNA 5'-UTR binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0008283//cell population proliferation;GO:0010608//posttranscriptional regulation of gene expression;GO:0016239//positive regulation of macroautophagy;GO:0017148//negative regulation of translation;GO:0031929//TOR signaling;GO:0038202//TORC1 signaling;GO:0045070//positive regulation of viral genome replication;GO:0045727//positive regulation of translation;GO:0045947//negative regulation of translational initiation;GO:0045948//positive regulation of translational initiation;GO:0048255//mRNA stabilization;GO:0072752//cellular response to rapamycin;GO:1990928//response to amino acid starvation	--
ENSG00000155508	19.546	16.728	16.508	15.589	16.036	21.927	851	739	563	482	622	646	CNOT8	CCR4-NOT transcription complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:9207]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12581	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006351//transcription, DNA-templated;GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0008284//positive regulation of cell population proliferation;GO:0031047//gene silencing by RNA;GO:0035195//gene silencing by miRNA;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0061014//positive regulation of mRNA catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000155511	0.688	0.539	1.278	0.734	0.467	0.836	64	60	87	47	39	53	GRIA1	glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Nervous system;Neurodegenerative disease;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko04024//cAMP signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04730//Long-term depression;ko05033//Nicotine addiction	K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197;K05197	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0008328//ionotropic glutamate receptor complex;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030666//endocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031901//early endosome membrane;GO:0032281//AMPA glutamate receptor complex;GO:0032590//dendrite membrane;GO:0032591//dendritic spine membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0044308//axonal spine;GO:0044309//neuron spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0060076//excitatory synapse;GO:0097060//synaptic membrane;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:0099544//perisynaptic space	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004971//AMPA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0030165//PDZ domain binding;GO:0038023//signaling receptor activity;GO:0099583//neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007616//long-term memory;GO:0031623//receptor internalization;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0060078//regulation of postsynaptic membrane potential;GO:0060292//long-term synaptic depression;GO:0071242//cellular response to ammonium ion;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration	--
ENSG00000155530	0.214	0.168	0.172	0.057	0.067	0.1	15	12	9	3	4	5	LRGUK	leucine rich repeats and guanylate kinase domain containing [Source:HGNC Symbol;Acc:HGNC:21964]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035082//axoneme assembly;GO:0046037//GMP metabolic process;GO:0046710//GDP metabolic process	--
ENSG00000155542	2.065	2.336	2.01	2.431	2.261	1.611	50	59	35	43	52	32	SETD9	SET domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28508]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000155545	7.333	6.236	5.892	4.257	5.384	6.462	772	650	444	340	463	507	MIER3	MIER family member 3 [Source:HGNC Symbol;Acc:HGNC:26678]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032991//protein-containing complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II	MYB
ENSG00000155561	11.183	11.532	10.317	7.658	9.465	11.086	1453	1506	990	737	1039	1048	NUP205	nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14310;K14310	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0044611//nuclear pore inner ring	GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore	GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051292//nuclear pore complex assembly	--
ENSG00000155592	2.813	2.961	2.979	2.704	2.64	2.682	434	437	308	309	344	301	ZKSCAN2	zinc finger with KRAB and SCAN domains 2 [Source:HGNC Symbol;Acc:HGNC:25677]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000155621	4.36	3.313	4.238	3.177	4.312	4.878	162	114	106	92	128	140	C9orf85	chromosome 9 open reading frame 85 [Source:HGNC Symbol;Acc:HGNC:28784]	-	-	-	-	-	-	-	--
ENSG00000155622	0	0	0	0	0	0	0	0	0	0	0	0	XAGE2	X antigen family member 2 [Source:HGNC Symbol;Acc:HGNC:4112]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000155629	0.201	0.196	0.204	0.145	0.261	0.202	15	17	15	7	20	10	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:30034]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04151//PI3K-Akt signaling pathway;ko04662//B cell receptor signaling pathway	K12230;K12230	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003953//NAD+ nucleosidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0050727//regulation of inflammatory response	--
ENSG00000155636	3.846	3.064	3.984	3.477	4.478	4.881	147	117	113	98	143	133	RBM45	RNA binding motif protein 45 [Source:HGNC Symbol;Acc:HGNC:24468]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:0030154//cell differentiation	--
ENSG00000155657	0.179	0.237	0.1	0.09	0.105	0.094	309	215	124	115	155	97	TTN	titin [Source:HGNC Symbol;Acc:HGNC:12403]	Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy	K12567;K12567	GO:0000794//condensed nuclear chromosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005865//striated muscle thin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030018//Z disc;GO:0031430//M band;GO:0031674//I band;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome;GO:1990733//titin-telethonin complex	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008307//structural constituent of muscle;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031433//telethonin binding;GO:0042802//identical protein binding;GO:0042805//actinin binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0051371//muscle alpha-actinin binding;GO:0097493//structural molecule activity conferring elasticity;GO:0106310//protein serine kinase activity	GO:0003300//cardiac muscle hypertrophy;GO:0006468//protein phosphorylation;GO:0006936//muscle contraction;GO:0006941//striated muscle contraction;GO:0007076//mitotic chromosome condensation;GO:0010628//positive regulation of gene expression;GO:0010737//protein kinase A signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030240//skeletal muscle thin filament assembly;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0035995//detection of muscle stretch;GO:0045214//sarcomere organization;GO:0045859//regulation of protein kinase activity;GO:0048769//sarcomerogenesis;GO:0050714//positive regulation of protein secretion;GO:0050790//regulation of catalytic activity;GO:0051592//response to calcium ion;GO:0055003//cardiac myofibril assembly;GO:0055008//cardiac muscle tissue morphogenesis;GO:0055013//cardiac muscle cell development;GO:0060048//cardiac muscle contraction	--
ENSG00000155659	0	0	0	0	0.095	0	0	0	0	0	3	0	VSIG4	V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K19822	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0001851//complement component C3b binding;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006957//complement activation, alternative pathway;GO:0032703//negative regulation of interleukin-2 production;GO:0042130//negative regulation of T cell proliferation;GO:0043031//negative regulation of macrophage activation;GO:0045087//innate immune response;GO:0045957//negative regulation of complement activation, alternative pathway"	--
ENSG00000155660	77.997	81.742	73.147	76.899	78.477	63.755	4537	4760	3129	3293	3851	2693	PDIA4	protein disulfide isomerase family A member 4 [Source:HGNC Symbol;Acc:HGNC:30167]	Genetic Information Processing;Organismal Systems;Human Diseases	"Folding, sorting and degradation;Endocrine system;Infectious disease: bacterial"	ko04141//Protein processing in endoplasmic reticulum;ko04918//Thyroid hormone synthesis;ko05110//Vibrio cholerae infection	K09582;K09582;K09582	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0042470//melanosome	GO:0003723//RNA binding;GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016853//isomerase activity	GO:0006457//protein folding;GO:0009306//protein secretion;GO:0034976//response to endoplasmic reticulum stress;GO:0061077//chaperone-mediated protein folding	--
ENSG00000155666	1.884	2.26	2.336	3.4	2.512	2.527	95	106	87	106	107	87	KDM8	lysine demethylase 8 [Source:HGNC Symbol;Acc:HGNC:25840]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003682//chromatin binding;GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0016787//hydrolase activity;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0106157//peptidyl-arginine 3-dioxygenase activity	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006325//chromatin organization;GO:0006508//proteolysis;GO:0007049//cell cycle;GO:0031648//protein destabilization;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0070544//histone H3-K36 demethylation"	--
ENSG00000155714	0	0.045	0	0.061	0	0.31	0	1	0	1	0	5	PDZD9	PDZ domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28740]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000155719	0.054	0.018	0	0.072	0.084	0.117	3	1	0	3	4	6	OTOA	otoancorin [Source:HGNC Symbol;Acc:HGNC:16378]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0110165//cellular anatomical entity	-	GO:0007160//cell-matrix adhesion;GO:0007605//sensory perception of sound;GO:0019226//transmission of nerve impulse	--
ENSG00000155729	7.236	6.478	6.897	6.911	7.242	7.348	396	356	281	286	338	294	KCTD18	potassium channel tetramerization domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26446]	-	-	-	-	-	-	GO:0051260//protein homooligomerization	--
ENSG00000155744	2.684	1.588	2.144	1.67	3.049	2.213	494	299	276	221	285	273	FAM126B	family with sequence similarity 126 member B [Source:HGNC Symbol;Acc:HGNC:28593]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000155749	0.071	0.061	0.032	0.083	0.028	0.096	3	1	1	1	1	3	FLACC1	flagellum associated containing coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:14439]	-	-	-	-	GO:0001520//outer dense fiber;GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0003674//molecular_function;GO:0005515//protein binding	-	--
ENSG00000155754	0.025	0	0	0	0	0.012	3	0	0	0	0	1	C2CD6	C2 calcium dependent domain containing 6 [Source:HGNC Symbol;Acc:HGNC:14438]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000155755	7.439	7.003	6.057	5.129	4.995	5.042	354	326	208	187	216	169	TMEM237	transmembrane protein 237 [Source:HGNC Symbol;Acc:HGNC:14432]	-	-	-	-	GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032391//photoreceptor connecting cilium;GO:0035869//ciliary transition zone;GO:0042995//cell projection;GO:0120199//cone photoreceptor outer segment;GO:0120200//rod photoreceptor outer segment	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0030111//regulation of Wnt signaling pathway;GO:0060271//cilium assembly	--
ENSG00000155760	4.509	4.716	4.312	6.584	5.934	7.165	429	451	303	464	477	496	FZD7	frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane	"GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010812//negative regulation of cell-substrate adhesion;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0016055//Wnt signaling pathway;GO:0019827//stem cell population maintenance;GO:0030182//neuron differentiation;GO:0033077//T cell differentiation in thymus;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035567//non-canonical Wnt signaling pathway;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0042327//positive regulation of phosphorylation;GO:0042666//negative regulation of ectodermal cell fate specification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0048103//somatic stem cell division;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060231//mesenchymal to epithelial transition;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0071300//cellular response to retinoic acid;GO:2000726//negative regulation of cardiac muscle cell differentiation"	--
ENSG00000155761	0.495	0.309	0.236	0.154	0.19	0.23	74	38.23	26	17	24	25	SPAG17	sperm associated antigen 17 [Source:HGNC Symbol;Acc:HGNC:26620]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:1990716//axonemal central apparatus	-	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0030030//cell projection organization;GO:1904158//axonemal central apparatus assembly	--
ENSG00000155792	1.013	0.99	1.118	0.615	0.533	0.408	54	53	44	24	24	12	DEPTOR	DEP domain containing MTOR interacting protein [Source:HGNC Symbol;Acc:HGNC:22953]	Environmental Information Processing;Cellular Processes	Signal transduction;Transport and catabolism	ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K20402;K20402	-	GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0032007//negative regulation of TOR signaling;GO:0035556//intracellular signal transduction;GO:0045792//negative regulation of cell size;GO:1903940//negative regulation of TORC2 signaling;GO:1904262//negative regulation of TORC1 signaling;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000155816	2.636	2.594	2.333	1.87	1.549	2.083	243	231	154	159	163	138	FMN2	formin 2 [Source:HGNC Symbol;Acc:HGNC:14074]	Organismal Systems	Development and regeneration	ko04320//Dorso-ventral axis formation	K02184	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0008017//microtubule binding	GO:0006974//cellular response to DNA damage stimulus;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016344//meiotic chromosome movement towards spindle pole;GO:0035556//intracellular signal transduction;GO:0040038//polar body extrusion after meiotic divisions;GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045010//actin nucleation;GO:0046907//intracellular transport;GO:0048477//oogenesis;GO:0051017//actin filament bundle assembly;GO:0051295//establishment of meiotic spindle localization;GO:0051758//homologous chromosome movement towards spindle pole in meiosis I anaphase;GO:0070649//formin-nucleated actin cable assembly;GO:0071456//cellular response to hypoxia;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000155827	20.073	16.187	17.067	12.084	16.6	11.055	1415	1329	819	635	828	657	RNF20	ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0033503//HULC complex	GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003730//mRNA 3'-UTR binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010390//histone monoubiquitination;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0030336//negative regulation of cell migration;GO:0031062//positive regulation of histone methylation;GO:0033523//histone H2B ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071894//histone H2B conserved C-terminal lysine ubiquitination;GO:1900364//negative regulation of mRNA polyadenylation;GO:2001168//positive regulation of histone H2B ubiquitination"	--
ENSG00000155833	0	0	0	0	0	0	0	0	0	0	0	0	CYLC2	cylicin 2 [Source:HGNC Symbol;Acc:HGNC:2583]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0033150//cytoskeletal calyx	GO:0005200//structural constituent of cytoskeleton	GO:0007010//cytoskeleton organization;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000155846	1.362	1.072	1.62	1.821	1.598	1.728	260	221	227	239	277	256	PPARGC1B	PPARG coactivator 1 beta [Source:HGNC Symbol;Acc:HGNC:30022]	Human Diseases	Endocrine and metabolic disease	ko04931//Insulin resistance	K17962	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016592//mediator complex	GO:0003676//nucleic acid binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0050682//AF-2 domain binding	"GO:0001503//ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0006390//mitochondrial transcription;GO:0007015//actin filament organization;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0042327//positive regulation of phosphorylation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP;GO:0060346//bone trabecula formation;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000155849	0.346	0.358	1.263	1.774	0.374	0.543	13	26	27	33	16	27	ELMO1	engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05132//Salmonella infection;ko05131//Shigellosis;ko05135//Yersinia infection;ko04062//Chemokine signaling pathway;ko05100//Bacterial invasion of epithelial cells	K12366;K12366;K12366;K12366;K12366	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032045//guanyl-nucleotide exchange factor complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	"GO:0006909//phagocytosis;GO:0006911//phagocytosis, engulfment;GO:0006915//apoptotic process;GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0030029//actin filament-based process;GO:0030036//actin cytoskeleton organization;GO:0048870//cell motility;GO:0050790//regulation of catalytic activity"	--
ENSG00000155850	7.441	6.247	5.981	4.986	5.243	5.479	1243	1049	738	617	740	666	SLC26A2	solute carrier family 26 member 2 [Source:HGNC Symbol;Acc:HGNC:10994]	Human Diseases	Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species	K14701	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0070062//extracellular exosome	GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity	GO:0001503//ossification;GO:0006811//ion transport;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0055085//transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000155858	2.1	2.279	2.137	1.774	1.955	1.947	286	312	215	179	225	193	LSM11	"LSM11, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:HGNC:30860]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005683//U7 snRNP;GO:0005697//telomerase holoenzyme complex;GO:0016604//nuclear body;GO:0071204//histone pre-mRNA 3'end processing complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0071209//U7 snRNA binding	GO:0006397//mRNA processing;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902275//regulation of chromatin organization	--
ENSG00000155868	3.646	4.883	5.349	5.112	4.5	4.047	138	159	140	124	115	100	MED7	mediator complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:2378]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016592//mediator complex;GO:0016604//nuclear body;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0016567//protein ubiquitination;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000155875	0.056	0.028	0.015	0.008	0	0.038	2	1	2	1	0	1	SAXO1	stabilizer of axonemal microtubules 1 [Source:HGNC Symbol;Acc:HGNC:28566]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005879//axonemal microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0009631//cold acclimation;GO:0030030//cell projection organization;GO:0034453//microtubule anchoring;GO:0045724//positive regulation of cilium assembly;GO:0050821//protein stabilization;GO:0070417//cellular response to cold	--
ENSG00000155876	36.091	41.396	42.13	39.931	36.83	41.729	1197	1380	1032	981	1032	1007	RRAGA	Ras related GTP binding A [Source:HGNC Symbol;Acc:HGNC:16963]	Human Diseases;Environmental Information Processing;Cellular Processes	Infectious disease: bacterial;Signal transduction;Transport and catabolism	ko05131//Shigellosis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K16185;K16185;K16185	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:1990130//GATOR1 complex;GO:1990131//Gtr1-Gtr2 GTPase complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051219//phosphoprotein binding	GO:0006915//apoptotic process;GO:0008219//cell death;GO:0009267//cellular response to starvation;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0032008//positive regulation of TOR signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034198//cellular response to amino acid starvation;GO:0034613//cellular protein localization;GO:0045918//negative regulation of cytolysis;GO:0071230//cellular response to amino acid stimulus;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000155886	0.013	0.031	0	0	0.01	0	3	7	0	0	2	0	SLC24A2	solute carrier family 24 member 2 [Source:HGNC Symbol;Acc:HGNC:10976]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044214//spanning component of plasma membrane	"GO:0005262//calcium channel activity;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007612//learning;GO:0007613//memory;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0036368//cone photoresponse recovery;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0071486//cellular response to high light intensity;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098703//calcium ion import across plasma membrane	--
ENSG00000155890	0	0	0	0	0	0	0	0	0	0	0	0	TRIM42	tripartite motif containing 42 [Source:HGNC Symbol;Acc:HGNC:19014]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000155893	12.187	12.344	11.579	9.991	9.011	10.835	674	689	491	453	482	419	PXYLP1	2-phosphoxylose phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:26303]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006024//glycosaminoglycan biosynthetic process;GO:0010909//positive regulation of heparan sulfate proteoglycan biosynthetic process;GO:0016311//dephosphorylation;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process	--
ENSG00000155897	0.36	0.419	0.717	0.515	0.555	0.731	33	37	48	35	43	21	ADCY8	adenylate cyclase 8 [Source:HGNC Symbol;Acc:HGNC:239]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Nervous system;Aging;Endocrine system;Endocrine system;Endocrine system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis"	K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048;K08048	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005905//clathrin-coated pit;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004016//adenylate cyclase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008294//calcium- and calmodulin-responsive adenylate cyclase activity;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0051721//protein phosphatase 2A binding	GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0003008//system process;GO:0006171//cAMP biosynthetic process;GO:0007165//signal transduction;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007611//learning or memory;GO:0007613//memory;GO:0007616//long-term memory;GO:0007626//locomotory behavior;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010255//glucose mediated signaling pathway;GO:0031915//positive regulation of synaptic plasticity;GO:0032793//positive regulation of CREB transcription factor activity;GO:0034199//activation of protein kinase A activity;GO:0035556//intracellular signal transduction;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0038003//G protein-coupled opioid receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0050796//regulation of insulin secretion;GO:0050804//modulation of chemical synaptic transmission;GO:0051259//protein complex oligomerization;GO:0051260//protein homooligomerization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0065008//regulation of biological quality;GO:0071277//cellular response to calcium ion;GO:0071315//cellular response to morphine;GO:0071333//cellular response to glucose stimulus;GO:0071377//cellular response to glucagon stimulus;GO:0080135//regulation of cellular response to stress;GO:0150076//neuroinflammatory response;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1900454//positive regulation of long-term synaptic depression;GO:1904322//cellular response to forskolin	--
ENSG00000155903	1.685	0.995	1.169	0.739	0.597	0.952	197	117	101	64	59	81	RASA2	RAS p21 protein activator 2 [Source:HGNC Symbol;Acc:HGNC:9872]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Cancer: overview	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05203//Viral carcinogenesis	K08053;K08053;K08053	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction	--
ENSG00000155906	5.98	7.477	6.299	4.864	5.52	6.639	233	287	182	148	178	180	RMND1	required for meiotic nuclear division 1 homolog [Source:HGNC Symbol;Acc:HGNC:21176]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0006412//translation;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000155918	0	0	0	0	0	0	0	0	0	0	0	0	RAET1L	retinoic acid early transcript 1L [Source:HGNC Symbol;Acc:HGNC:16798]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07987	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0002376//immune system process	--
ENSG00000155926	0	0	0	0	0.019	0	0	0	0	0	1	0	SLA	Src like adaptor [Source:HGNC Symbol;Acc:HGNC:10902]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043197//dendritic spine	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009966//regulation of signal transduction;GO:0030154//cell differentiation;GO:0045087//innate immune response	--
ENSG00000155957	89.662	76.338	93.676	82.567	82.298	94.842	1749	1517	1373	1195.33	1373	1344.39	TMBIM4	transmembrane BAX inhibitor motif containing 4 [Source:HGNC Symbol;Acc:HGNC:24257]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0050848//regulation of calcium-mediated signaling	--
ENSG00000155959	17.214	15.434	15.835	14.902	14.231	14.269	577	520	392	370	403	348	VBP1	VHL binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12662]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0016272//prefoldin complex;GO:0043231//intracellular membrane-bounded organelle	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007017//microtubule-based process;GO:0007021//tubulin complex assembly;GO:0050821//protein stabilization;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000155961	3.447	3.345	2.888	2.021	2.809	2.932	244	238	151	106	168	151	RAB39B	"RAB39B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16499]"	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04140//Autophagy - animal	K07925;K07925;K07925	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043005//neuron projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0031489//myosin V binding	GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032482//Rab protein signal transduction;GO:0050808//synapse organization	--
ENSG00000155962	0.129	0.073	0.149	0.074	0.087	0.287	7	4	6	3	4	5	CLIC2	chloride intracellular channel 2 [Source:HGNC Symbol;Acc:HGNC:2063]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0004602//glutathione peroxidase activity;GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006749//glutathione metabolic process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0034765//regulation of ion transmembrane transport;GO:0051099//positive regulation of binding;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0098869//cellular oxidant detoxification;GO:1902476//chloride transmembrane transport	--
ENSG00000155966	0.427	0.601	0.45	0.492	0.307	0.393	64	65	47	43	55	43	AFF2	AF4/FMR2 family member 2 [Source:HGNC Symbol;Acc:HGNC:3776]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck	GO:0002151//G-quadruplex RNA binding;GO:0003723//RNA binding	GO:0006397//mRNA processing;GO:0007420//brain development;GO:0007611//learning or memory;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0035063//nuclear speck organization;GO:0043484//regulation of RNA splicing	AF-4
ENSG00000155970	1.474	1.373	0.982	1.24	1.073	1.129	122	76	60	76	60	68	MICU3	mitochondrial calcium uptake family member 3 [Source:HGNC Symbol;Acc:HGNC:27820]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990246//uniplex complex	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0036444//calcium import into the mitochondrion;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000155974	2.483	1.48	2.259	2.319	3.358	2.014	144	141	113	80	136	98	GRIP1	glutamate receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18708]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0030159//signaling receptor complex adaptor activity;GO:0035259//glucocorticoid receptor binding	"GO:0016358//dendrite development;GO:0035556//intracellular signal transduction;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0150012//positive regulation of neuron projection arborization"	--
ENSG00000155975	15.374	13.053	10.692	11.853	12.802	13.367	754.54	589.76	387.48	393.49	477.46	448.38	VPS37A	VPS37A subunit of ESCRT-I [Source:HGNC Symbol;Acc:HGNC:24928]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12185	GO:0000813//ESCRT I complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043657//host cell	GO:0005515//protein binding	GO:0006612//protein targeting to membrane;GO:0006623//protein targeting to vacuole;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046907//intracellular transport;GO:0075733//intracellular transport of virus	--
ENSG00000155980	0.749	0.249	0.333	0.212	0.446	2.296	33	30	25	18	22	31	KIF5A	kinesin family member 5A [Source:HGNC Symbol;Acc:HGNC:6323]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Nervous system;Cancer: specific types	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection;ko04144//Endocytosis;ko04728//Dopaminergic synapse;ko05223//Non-small cell lung cancer	K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0032839//dendrite cytoplasm;GO:0035253//ciliary rootlet;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding	GO:0007018//microtubule-based movement;GO:0007268//chemical synaptic transmission;GO:0007411//axon guidance;GO:0016192//vesicle-mediated transport;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0048489//synaptic vesicle transport;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex;GO:0099641//anterograde axonal protein transport;GO:1990049//retrograde neuronal dense core vesicle transport	--
ENSG00000156006	0.225	0.037	0	0	0.133	0	6	1	0	0	3	0	NAT2	N-acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7646]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko05204//Chemical carcinogenesis - DNA adducts;ko00232//Caffeine metabolism	K00622;K00622;K00622;K00622	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004060//arylamine N-acetyltransferase activity;GO:0005515//protein binding;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006805//xenobiotic metabolic process	--
ENSG00000156009	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA8	MAGE family member A8 [Source:HGNC Symbol;Acc:HGNC:6806]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000156011	4.902	4.122	3.543	2.481	3.495	3.289	880	799	561	404	549	521	PSD3	pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12494	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000156017	4.422	4.7	4.483	3.819	5.862	5.422	342	303	187	152	253	247	CARNMT1	carnosine N-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23435]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K19787;K19787	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0030735//carnosine N-methyltransferase activity;GO:0042803//protein homodimerization activity	GO:0006548//histidine catabolic process;GO:0032259//methylation;GO:0035498//carnosine metabolic process	--
ENSG00000156026	13.204	13.089	13.195	11.936	11.727	12.804	796	802	574	523	590	563	MCU	mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cell growth and death;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04621//NOD-like receptor signaling pathway;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia	K20858;K20858;K20858;K20858;K20858;K20858;K20858;K20858;K20858	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0034704//calcium channel complex;GO:1990246//uniplex complex	GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015292//uniporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0019722//calcium-mediated signaling;GO:0032024//positive regulation of insulin secretion;GO:0036444//calcium import into the mitochondrion;GO:0042593//glucose homeostasis;GO:0051259//protein complex oligomerization;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0070588//calcium ion transmembrane transport;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0090141//positive regulation of mitochondrial fission;GO:0090527//actin filament reorganization	--
ENSG00000156030	3.884	4.014	4.818	4.06	4.538	4.999	627	652	576	486	620	545	MIDEAS	mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated"	Others
ENSG00000156042	1.636	1.056	0.945	1.001	1.057	1.041	143	91	67	58	70	61	CFAP70	cilia and flagella associated protein 70 [Source:HGNC Symbol;Acc:HGNC:30726]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0003341//cilium movement;GO:0008150//biological_process;GO:0060271//cilium assembly	--
ENSG00000156049	1.718	1.671	1.203	0.626	0.777	1.061	89	87	46	24	34	40	GNA14	G protein subunit alpha 14 [Source:HGNC Symbol;Acc:HGNC:4382]	Environmental Information Processing;Human Diseases;Human Diseases	Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic	ko04020//Calcium signaling pathway;ko05146//Amoebiasis;ko05142//Chagas disease	K04636;K04636;K04636	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001508//action potential;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway	--
ENSG00000156050	2.207	2.386	2.271	2.056	2.485	1.678	171	187	128	117	162	93	FAM161B	FAM161 centrosomal protein B [Source:HGNC Symbol;Acc:HGNC:19854]	-	-	-	-	GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding	GO:0008150//biological_process;GO:0044782//cilium organization	--
ENSG00000156052	18.676	15.988	14.436	10.573	11.177	12.054	2666	2294	1522	1118	1348	1252	GNAQ	G protein subunit alpha q [Source:HGNC Symbol;Acc:HGNC:4390]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: parasitic;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Signal transduction;Endocrine system;Circulatory system;Nervous system;Immune system;Signal transduction;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Environmental adaptation;Endocrine system;Sensory system;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Digestive system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system;Excretory system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04062//Chemokine signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption"	K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634;K04634	GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	"GO:0001508//action potential;GO:0006469//negative regulation of protein kinase activity;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0007596//blood coagulation;GO:0007603//phototransduction, visible light;GO:0009649//entrainment of circadian clock;GO:0050821//protein stabilization;GO:0060828//regulation of canonical Wnt signaling pathway"	--
ENSG00000156076	0.073	0.049	0.066	0.132	0.029	0.067	3	2	2	4	1	2	WIF1	WNT inhibitory factor 1 [Source:HGNC Symbol;Acc:HGNC:18081]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K01691	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding	GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0048856//anatomical structure development	--
ENSG00000156096	0	0	0	0	0	0	0	0	0	0	0	0	UGT2B4	UDP glucuronosyltransferase family 2 member B4 [Source:HGNC Symbol;Acc:HGNC:12553]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0008210//estrogen metabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000156097	2.719	2.484	1.98	1.347	1.442	1.528	204	200	111	84	92	81	GPR61	G protein-coupled receptor 61 [Source:HGNC Symbol;Acc:HGNC:13300]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:1990763//arrestin family protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling	--
ENSG00000156103	1.224	0.386	0.339	0.208	0.381	0.407	153	93	60	37	74	71	MMP16	matrix metallopeptidase 16 [Source:HGNC Symbol;Acc:HGNC:7162]	Human Diseases;Organismal Systems	Cancer: overview;Endocrine system	"ko05206//MicroRNAs in cancer;ko04928//Parathyroid hormone synthesis, secretion and action"	K07996;K07996	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001958//endochondral ossification;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0035988//chondrocyte proliferation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050790//regulation of catalytic activity;GO:0060348//bone development;GO:0097094//craniofacial suture morphogenesis	--
ENSG00000156110	7.299	6.942	6.671	6.096	5.053	4.854	242	218	165	134	148	132	ADK	adenosine kinase [Source:HGNC Symbol;Acc:HGNC:257]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00856;K00856	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004001//adenosine kinase activity;GO:0004136//deoxyadenosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0046872//metal ion binding"	GO:0006166//purine ribonucleoside salvage;GO:0006167//AMP biosynthetic process;GO:0006175//dATP biosynthetic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0016310//phosphorylation;GO:0032263//GMP salvage;GO:0034654//nucleobase-containing compound biosynthetic process;GO:0044209//AMP salvage;GO:0044238//primary metabolic process;GO:0044281//small molecule metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0072522//purine-containing compound biosynthetic process;GO:0106383//dAMP salvage	--
ENSG00000156113	1.43	1.33	0.534	1.085	1.04	1.136	138	120	34	48	59	47	KCNMA1	potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284]	Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Digestive system;Digestive system;Endocrine system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04911//Insulin secretion;ko04924//Renin secretion	K04936;K04936;K04936;K04936;K04936;K04936	GO:0005886//plasma membrane;GO:0005901//caveola;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0045211//postsynaptic membrane	GO:0003779//actin binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0022839//ion gated channel activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0060072//large conductance calcium-activated potassium channel activity	GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006970//response to osmotic stress;GO:0030007//cellular potassium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0034465//response to carbon monoxide;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043065//positive regulation of apoptotic process;GO:0045794//negative regulation of cell volume;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0060073//micturition;GO:0060083//smooth muscle contraction involved in micturition;GO:0060087//relaxation of vascular associated smooth muscle;GO:0071805//potassium ion transmembrane transport	--
ENSG00000156127	0	0	0	0	0.125	0	0	0	0	0	2	0	BATF	basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958]	Human Diseases	Cancer: overview	ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K09034	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001819//positive regulation of cytokine production;GO:0002320//lymphoid progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0030154//cell differentiation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0042832//defense response to protozoan;GO:0043011//myeloid dendritic cell differentiation;GO:0045064//T-helper 2 cell differentiation;GO:0045190//isotype switching;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060218//hematopoietic stem cell differentiation;GO:0072539//T-helper 17 cell differentiation;GO:0072540//T-helper 17 cell lineage commitment;GO:0140467//integrated stress response signaling;GO:2000319//regulation of T-helper 17 cell differentiation"	TF_bZIP
ENSG00000156136	7.757	6.093	6.752	6.147	5.485	7.538	414	325	265	242	250	290	DCK	deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K00893;K00893;K00893	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004136//deoxyadenosine kinase activity;GO:0004137//deoxycytidine kinase activity;GO:0004138//deoxyguanosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019136//deoxynucleoside kinase activity;GO:0042803//protein homodimerization activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0016310//phosphorylation;GO:0044249//cellular biosynthetic process;GO:0106383//dAMP salvage;GO:1901576//organic substance biosynthetic process	--
ENSG00000156140	2.406	1.833	1.589	1.72	2.158	2.08	303	221	152	162	204	196	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif 3 [Source:HGNC Symbol;Acc:HGNC:219]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0006508//proteolysis;GO:0010573//vascular endothelial growth factor production;GO:0016485//protein processing;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process;GO:0032964//collagen biosynthetic process;GO:0097435//supramolecular fiber organization;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway	--
ENSG00000156150	0.271	0.319	0.601	0.233	0.525	0.271	11	13	18	7	18	8	ALX3	ALX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:449]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0042981//regulation of apoptotic process;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000156162	13.694	10.589	10.435	9.503	9.427	12.43	1462	1118	860	734	829	884	DPY19L4	dpy-19 like 4 [Source:HGNC Symbol;Acc:HGNC:27829]	-	-	-	-	GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	--
ENSG00000156170	3.627	3.136	3.6	2.907	4.377	4.988	104	94	74	66	85	90	NDUFAF6	NADH:ubiquinone oxidoreductase complex assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:28625]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18163	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0009058//biosynthetic process;GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000156171	11.965	12.851	12.676	11.651	11.856	13.304	527	575	413	379	442	424	DRAM2	DNA damage regulated autophagy modulator 2 [Source:HGNC Symbol;Acc:HGNC:28769]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	-	GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0007601//visual perception;GO:0010506//regulation of autophagy;GO:0045494//photoreceptor cell maintenance	--
ENSG00000156172	2.901	2.125	1.7	1.695	2.17	1.845	201	148	87	87	127	93	CFAP418	cilia and flagella associated protein 418 [Source:HGNC Symbol;Acc:HGNC:27232]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0097546//ciliary base	GO:0005515//protein binding	GO:0008594//photoreceptor cell morphogenesis	--
ENSG00000156194	0	0	0	0	0	0	0	0	0	0	0	0	PPEF2	protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]	Organismal Systems	Sensory system	ko04745//Phototransduction - fly	K13807	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0030544//Hsp70 protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0046872//metal ion binding;GO:0051879//Hsp90 protein binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007601//visual perception;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0043405//regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0043506//regulation of JUN kinase activity;GO:0050896//response to stimulus;GO:0050906//detection of stimulus involved in sensory perception	--
ENSG00000156206	0.299	0.371	0.324	0	0.538	0.278	10	7	8	0	8	3	CFAP161	cilia and flagella associated protein 161 [Source:HGNC Symbol;Acc:HGNC:26782]	-	-	-	-	GO:0031514//motile cilium	GO:0005515//protein binding	GO:0060271//cilium assembly	--
ENSG00000156218	44.233	40.955	38.78	28.292	33.572	33.081	6576	6142	4278	3125	4220	3582	ADAMTSL3	ADAMTS like 3 [Source:HGNC Symbol;Acc:HGNC:14633]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding	GO:0030198//extracellular matrix organization	--
ENSG00000156219	0	0.032	0	0	0	0	0	1	0	0	0	0	ART3	ADP-ribosyltransferase 3 (inactive) [Source:HGNC Symbol;Acc:HGNC:725]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0070062//extracellular exosome	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106274//NAD+-protein-arginine ADP-ribosyltransferase activity;GO:0106275//NADP+-protein-arginine ADP-ribosyltransferase activity	GO:0006471//protein ADP-ribosylation;GO:0018120//peptidyl-arginine ADP-ribosylation	--
ENSG00000156222	0	0	0	0	0	0	0	0	0	0	0	0	SLC28A1	solute carrier family 28 member 1 [Source:HGNC Symbol;Acc:HGNC:11001]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031526//brush border membrane	GO:0005337//nucleoside transmembrane transporter activity;GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005415//nucleoside:sodium symporter activity;GO:0015212//cytidine transmembrane transporter activity;GO:0015213//uridine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015389//pyrimidine- and adenine-specific:sodium symporter activity;GO:1901474//azole transmembrane transporter activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0015855//pyrimidine nucleobase transport;GO:0015858//nucleoside transport;GO:0015861//cytidine transport;GO:0015862//uridine transport;GO:0045117//azole transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:1901642//nucleoside transmembrane transport;GO:1904823//purine nucleobase transmembrane transport	--
ENSG00000156232	2.438	2.116	2.483	2.093	1.868	2.442	258	225	194	164	167	188	WHAMM	"WASP homolog associated with actin, golgi membranes and microtubules [Source:HGNC Symbol;Acc:HGNC:30493]"	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K20479	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0031267//small GTPase binding;GO:0071933//Arp2/3 complex binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007015//actin filament organization;GO:0030032//lamellipodium assembly;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0048041//focal adhesion assembly;GO:0051127//positive regulation of actin nucleation;GO:0090527//actin filament reorganization;GO:0097320//plasma membrane tubulation	--
ENSG00000156234	0	0	0	0	0.097	0	0	0	0	0	2	0	CXCL13	C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K10032;K10032;K10032	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding;GO:0031724//CXCR5 chemokine receptor binding;GO:0031735//CCR10 chemokine receptor binding;GO:0045236//CXCR chemokine receptor binding;GO:0048018//receptor ligand activity;GO:0048248//CXCR3 chemokine receptor binding	GO:0002467//germinal center formation;GO:0002518//lymphocyte chemotaxis across high endothelial venule;GO:0002544//chronic inflammatory response;GO:0002920//regulation of humoral immune response;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0009605//response to external stimulus;GO:0010820//positive regulation of T cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0033625//positive regulation of integrin activation;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0035754//B cell chemotaxis;GO:0035768//endothelial cell chemotaxis to fibroblast growth factor;GO:0042742//defense response to bacterium;GO:0045765//regulation of angiogenesis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0090630//activation of GTPase activity;GO:2000545//negative regulation of endothelial cell chemotaxis to fibroblast growth factor	--
ENSG00000156239	5.532	5.48	5.893	6.907	6.529	6.487	445	461	367	363	414	373	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:16021]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0035657//eRF1 methyltransferase complex	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0009007//site-specific DNA-methyltransferase (adenine-specific) activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0030792//methylarsonite methyltransferase activity;GO:0036009//protein-glutamine N-methyltransferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0006325//chromatin organization;GO:0009404//toxin metabolic process;GO:0018364//peptidyl-glutamine methylation;GO:0018872//arsonoacetate metabolic process;GO:0030307//positive regulation of cell growth;GO:0032259//methylation;GO:0032775//DNA methylation on adenine;GO:0034968//histone lysine methylation	--
ENSG00000156253	5.222	5.509	6.07	4.927	4.748	4.583	332	352	285	232	255	212	RWDD2B	RWD domain containing 2B [Source:HGNC Symbol;Acc:HGNC:1302]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000156256	6.212	5.402	4.677	4.493	4.605	4.328	379	332	210	203	237	192	USP16	ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding	"GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010468//regulation of gene expression;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045901//positive regulation of translational elongation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051289//protein homotetramerization;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0070537//histone H2A K63-linked deubiquitination;GO:0140014//mitotic nuclear division"	--
ENSG00000156261	72.678	69.35	64.745	61.502	59.085	59.851	2796	2682	1839	1752	1920	1675	CCT8	chaperonin containing TCP1 subunit 8 [Source:HGNC Symbol;Acc:HGNC:1623]	-	-	-	-	GO:0002199//zona pellucida receptor complex;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0042995//cell projection;GO:0044297//cell body;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0045296//cadherin binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0046931//pore complex assembly;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000156265	1.525	1.76	0.557	0.941	1.538	0.678	54	49	12	18	27	12	MAP3K7CL	MAP3K7 C-terminal like [Source:HGNC Symbol;Acc:HGNC:16457]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000156269	0	0	0	0	0	0	0	0	0	0	0	0	NAA11	"N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0031415//NatA complex	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:1990189//peptide-serine-N-acetyltransferase activity;GO:1990190//peptide-glutamate-N-acetyltransferase activity	GO:0006474//N-terminal protein amino acid acetylation;GO:0017198//N-terminal peptidyl-serine acetylation;GO:0018002//N-terminal peptidyl-glutamic acid acetylation	--
ENSG00000156273	10.33	7.217	7.212	6.051	5.578	6.101	874	644	486	392	480	495	BACH1	BTB domain and CNC homolog 1 [Source:HGNC Symbol;Acc:HGNC:935]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0020037//heme binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000117//regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia"	TF_bZIP
ENSG00000156282	0	0	0	0	0	0	0	0	0	0	0	0	CLDN17	claudin 17 [Source:HGNC Symbol;Acc:HGNC:2038]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex	GO:0005198//structural molecule activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000156284	0	0	0	0	0	0	0	0	0	0	0	0	CLDN8	claudin 8 [Source:HGNC Symbol;Acc:HGNC:2050]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000156298	4.428	4.943	4.834	6.939	5.72	6.162	160	179.52	129	185.71	169	162	TSPAN7	tetraspanin 7 [Source:HGNC Symbol;Acc:HGNC:11854]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K06571	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000156299	0.594	0.598	0.559	0.231	0.402	0.586	68	73	56	23	50	50	TIAM1	TIAM Rac1 associated GEF 1 [Source:HGNC Symbol;Acc:HGNC:11805]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes	Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Immune system;Cellular community - eukaryotes	ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04062//Chemokine signaling pathway;ko04530//Tight junction	K05731;K05731;K05731;K05731;K05731;K05731;K05731	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044291//cell-cell contact zone;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019900//kinase binding	"GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0016601//Rac protein signal transduction;GO:0030335//positive regulation of cell migration;GO:0032092//positive regulation of protein binding;GO:0034622//cellular protein-containing complex assembly;GO:0035556//intracellular signal transduction;GO:0048013//ephrin receptor signaling pathway;GO:0050772//positive regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0090630//activation of GTPase activity;GO:1904338//regulation of dopaminergic neuron differentiation;GO:2000050//regulation of non-canonical Wnt signaling pathway"	--
ENSG00000156304	9.504	8.607	8.951	7.515	10.564	9.981	833	760	581	488	780	638	SCAF4	SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008022//protein C-terminus binding;GO:1990269//RNA polymerase II C-terminal domain phosphoserine binding	"GO:0006397//mRNA processing;GO:2000805//negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled"	--
ENSG00000156313	0.678	0.736	0.703	0.604	0.85	0.805	40	41	27	22	42	27	RPGR	retinitis pigmentosa GTPase regulator [Source:HGNC Symbol;Acc:HGNC:10295]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0007601//visual perception;GO:0030030//cell projection organization;GO:0042073//intraciliary transport;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus;GO:0060271//cilium assembly	--
ENSG00000156345	6.543	6.947	7.192	7.111	6.23	7.143	289	305	235	234	236	231	CDK20	cyclin dependent kinase 20 [Source:HGNC Symbol;Acc:HGNC:21420]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001843//neural tube closure;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0021508//floor plate formation;GO:0031076//embryonic camera-type eye development;GO:0048706//embryonic skeletal system development;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060021//roof of mouth development;GO:0061512//protein localization to cilium;GO:1901620//regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:1903317//regulation of protein maturation;GO:1990403//embryonic brain development	--
ENSG00000156374	2.259	1.802	1.46	2.678	2.386	2.252	104	84	50	92	93	76	PCGF6	polycomb group ring finger 6 [Source:HGNC Symbol;Acc:HGNC:21156]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11470	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0036353//histone H2A-K119 monoubiquitination;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000156381	6.61	6.476	7.999	10.632	9.377	9.805	701.76	703.07	615.92	725.35	764.26	734.28	ANKRD9	ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0031466//Cul5-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006878//cellular copper ion homeostasis;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000156384	2.148	2.106	2.085	1.775	2.25	1.344	66	66	48	39	58	29	SFR1	SWI5 dependent homologous recombination repair protein 1 [Source:HGNC Symbol;Acc:HGNC:29574]	-	-	-	-	GO:0005634//nucleus;GO:0032798//Swi5-Sfr1 complex	GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071391//cellular response to estrogen stimulus"	--
ENSG00000156395	0.086	0.026	0.012	0.035	0.061	0.059	10	3	1	3	6	5	SORCS3	sortilin related VPS10 domain containing receptor 3 [Source:HGNC Symbol;Acc:HGNC:16699]	-	-	-	-	GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity	GO:0007218//neuropeptide signaling pathway;GO:0007612//learning;GO:0007613//memory;GO:1900452//regulation of long-term synaptic depression	--
ENSG00000156398	0.635	1.544	1.405	1.337	1.342	0.649	41	54	29	30	48	22	SFXN2	sideroflexin 2 [Source:HGNC Symbol;Acc:HGNC:16086]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022889//serine transmembrane transporter activity	GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0140300//serine import into mitochondrion;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000156411	37.428	34.386	38.844	42.686	29.02	40.059	483	449	370	406	319	374	ATP5MJ	ATP synthase membrane subunit j [Source:HGNC Symbol;Acc:HGNC:1188]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0015986//ATP synthesis coupled proton transport	--
ENSG00000156413	0	0	0	0	0	0	0	0	0	0	0	0	FUT6	fucosyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:4017]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07634;K07634	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0036065//fucosylation;GO:0036071//N-glycan fucosylation;GO:0042355//L-fucose catabolic process	--
ENSG00000156414	0.059	0.102	0.095	0.082	0	0	5	8	7	6	0	0	TDRD9	tudor domain containing 9 [Source:HGNC Symbol;Acc:HGNC:20122]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071547//piP-body	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000156427	0.386	0.48	0.098	1.336	1.457	1.791	16	20	3	41	51	54	FGF18	fibroblast growth factor 18 [Source:HGNC Symbol;Acc:HGNC:3674]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008083//growth factor activity	GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001957//intramembranous ossification;GO:0001958//endochondral ossification;GO:0002063//chondrocyte development;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030334//regulation of cell migration;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0043406//positive regulation of MAP kinase activity;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045766//positive regulation of angiogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor	--
ENSG00000156453	0.819	1.096	1.046	0.604	2.005	0.93	68	93	47	35	70	61	PCDH1	protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0007399//nervous system development	--
ENSG00000156463	1.363	1.103	1.367	0.743	1.145	0.906	88	79	69	40	68	47	SH3RF2	SH3 domain containing ring finger 2 [Source:HGNC Symbol;Acc:HGNC:26299]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0016740//transferase activity;GO:0019902//phosphatase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0030335//positive regulation of cell migration;GO:0031397//negative regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0046328//regulation of JNK cascade;GO:0046329//negative regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0051865//protein autoubiquitination	--
ENSG00000156466	5.065	4.561	1.723	2.437	2.444	1.607	390	353	98	139	159	90	GDF6	growth differentiation factor 6 [Source:HGNC Symbol;Acc:HGNC:4221]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K20012;K20012;K20012	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0042802//identical protein binding	"GO:0001656//metanephros development;GO:0006915//apoptotic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032924//activin receptor signaling pathway;GO:0035788//cell migration involved in metanephros development;GO:0045444//fat cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:1900745//positive regulation of p38MAPK cascade;GO:1990009//retinal cell apoptotic process"	--
ENSG00000156467	91.937	87.318	95.645	89.6	74.257	93.177	2878	2718	2224	2196	2142	2143	UQCRB	ubiquinol-cytochrome c reductase binding protein [Source:HGNC Symbol;Acc:HGNC:12582]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417;K00417	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding	"GO:0006119//oxidative phosphorylation;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0009060//aerobic respiration;GO:0045333//cellular respiration"	--
ENSG00000156469	4.976	4.656	5.409	4.093	5.079	5.754	145	142	118	92	123	109	MTERF3	mitochondrial transcription termination factor 3 [Source:HGNC Symbol;Acc:HGNC:24258]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0042254//ribosome biogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0061668//mitochondrial ribosome assembly"	--
ENSG00000156471	29.472	30.619	31.901	36.419	31.913	35.47	1841	1865	1421	1599	1705	1618	PTDSS1	phosphatidylserine synthase 1 [Source:HGNC Symbol;Acc:HGNC:9587]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K08729;K08729	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0106245//L-serine-phosphatidylethanolamine phosphatidyltransferase activity;GO:0106258//L-serine-phosphatidylcholine phosphatidyltransferase activity	GO:0006629//lipid metabolic process;GO:0006659//phosphatidylserine biosynthetic process;GO:0008654//phospholipid biosynthetic process	--
ENSG00000156475	0.234	0.385	0.298	0.261	0.223	0.316	15	18	13	9	16	10	PPP2R2B	protein phosphatase 2 regulatory subunit Bbeta [Source:HGNC Symbol;Acc:HGNC:9305]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway	K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354	GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0006915//apoptotic process;GO:0050790//regulation of catalytic activity;GO:0070262//peptidyl-serine dephosphorylation	--
ENSG00000156482	386.585	376.603	379.073	423.196	343.789	340.07	3997	3900	2888	3237	3001	2560	RPL30	ribosomal protein L30 [Source:HGNC Symbol;Acc:HGNC:10333]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02908;K02908	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0031640//killing of cells of other organism;GO:0050829//defense response to Gram-negative bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000156486	0.018	0.011	0.06	0.075	0.032	0.025	2	1	4	5	3	2	KCNS2	potassium voltage-gated channel modifier subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:6301]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1902259//regulation of delayed rectifier potassium channel activity	--
ENSG00000156500	0.638	1.916	0.997	0.608	0.645	1.005	32.97	37.08	37	21.92	28.07	26.48	PABIR3	PABIR family member 3 [Source:HGNC Symbol;Acc:HGNC:25202]	-	-	-	-	-	GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity	--
ENSG00000156502	5.722	7.145	6.035	5.728	5.806	7.41	294	369	229	218	252	277	SUPV3L1	Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:0045025//mitochondrial degradosome	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0016887//ATP hydrolysis activity;GO:0034458//3'-5' RNA helicase activity;GO:0042803//protein homodimerization activity"	GO:0000958//mitochondrial mRNA catabolic process;GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0000965//mitochondrial RNA 3'-end processing;GO:0006310//DNA recombination;GO:0006401//RNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0032508//DNA duplex unwinding;GO:0035945//mitochondrial ncRNA surveillance;GO:0035946//mitochondrial mRNA surveillance;GO:0043066//negative regulation of apoptotic process;GO:0070584//mitochondrion morphogenesis;GO:2000827//mitochondrial RNA surveillance	--
ENSG00000156504	4.023	4.006	3.42	3.878	4.387	3.843	301	265	211	206	218	225	PABIR2	PABIR family member 2 [Source:HGNC Symbol;Acc:HGNC:30490]	-	-	-	-	GO:0005581//collagen trimer	GO:0004865//protein serine/threonine phosphatase inhibitor activity	GO:0043086//negative regulation of catalytic activity	--
ENSG00000156508	7473.5	7848.955	7277.162	7801.974	7212.973	6344.231	279474	294668.05	201271	216501	227675	172856.46	EEF1A1	eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]	Human Diseases;Genetic Information Processing;Human Diseases	Infectious disease: parasitic;Translation;Infectious disease: bacterial	ko05140//Leishmaniasis;ko03013//Nucleocytoplasmic transport;ko05134//Legionellosis	K03231;K03231;K03231	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030864//cortical actin cytoskeleton;GO:0032587//ruffle membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0098574//cytoplasmic side of lysosomal membrane;GO:1904813//ficolin-1-rich granule lumen	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1900022//regulation of D-erythro-sphingosine kinase activity;GO:1904714//regulation of chaperone-mediated autophagy	--
ENSG00000156509	0.03	0.093	0.127	0.021	0.252	0.042	2	6	6	1	14	2	FBXO43	F-box protein 43 [Source:HGNC Symbol;Acc:HGNC:28521]	Cellular Processes	Cell growth and death	ko04114//Oocyte meiosis	K10318	GO:0005634//nucleus	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007088//regulation of mitotic nuclear division;GO:0016567//protein ubiquitination;GO:0045835//negative regulation of meiotic nuclear division;GO:0051321//meiotic cell cycle	--
ENSG00000156510	2.877	2.587	2.091	1.568	2.203	3.211	218	197	117	88	141	177	HKDC1	hexokinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23302]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: bacterial;Endocrine system;Signal transduction;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Biosynthesis of other secondary metabolites	"ko01100//Metabolic pathways;ko05131//Shigellosis;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00524//Neomycin, kanamycin and gentamicin biosynthesis"	K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0031966//mitochondrial membrane	"GO:0000166//nucleotide binding;GO:0004340//glucokinase activity;GO:0004396//hexokinase activity;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008865//fructokinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019158//mannokinase activity"	GO:0001678//cellular glucose homeostasis;GO:0005975//carbohydrate metabolic process;GO:0006096//glycolytic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0051156//glucose 6-phosphate metabolic process	--
ENSG00000156515	64.319	61.442	63.291	57.333	55.697	63.208	4810	4625	3472	3173	3495	3444	HK1	hexokinase 1 [Source:HGNC Symbol;Acc:HGNC:4922]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: bacterial;Endocrine system;Signal transduction;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Biosynthesis of other secondary metabolites	"ko01100//Metabolic pathways;ko05131//Shigellosis;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00524//Neomycin, kanamycin and gentamicin biosynthesis"	K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0045121//membrane raft	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004340//glucokinase activity;GO:0004396//hexokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008865//fructokinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019158//mannokinase activity;GO:0042834//peptidoglycan binding;GO:0047931//glucosamine kinase activity"	GO:0001678//cellular glucose homeostasis;GO:0002376//immune system process;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0005975//carbohydrate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006013//mannose metabolic process;GO:0006096//glycolytic process;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0045087//innate immune response;GO:0046835//carbohydrate phosphorylation;GO:0051156//glucose 6-phosphate metabolic process;GO:0061621//canonical glycolysis;GO:0072655//establishment of protein localization to mitochondrion;GO:0072656//maintenance of protein location in mitochondrion	--
ENSG00000156521	4.125	3.686	5.134	5.635	5.598	6.127	321	287	295	322	367	347	TYSND1	trypsin like peroxisomal matrix peptidase 1 [Source:HGNC Symbol;Acc:HGNC:28531]	-	-	-	-	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0002020//protease binding;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0016485//protein processing;GO:0031998//regulation of fatty acid beta-oxidation	--
ENSG00000156531	7.567	6.178	6.265	4.191	5.737	5.781	609	494	385	286	337	370	PHF6	PHD finger protein 6 [Source:HGNC Symbol;Acc:HGNC:18145]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0043021//ribonucleoprotein complex binding;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding;GO:0097110//scaffold protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001835//blastocyst hatching;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000156535	0.714	0.929	0.434	0.375	0.642	0.664	134	175	60	52	102	91	CD109	CD109 molecule [Source:HGNC Symbol;Acc:HGNC:21685]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031092//platelet alpha granule membrane;GO:0031225//anchored component of membrane	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0050431//transforming growth factor beta binding	GO:0001933//negative regulation of protein phosphorylation;GO:0001942//hair follicle development;GO:0010466//negative regulation of peptidase activity;GO:0010839//negative regulation of keratinocyte proliferation;GO:0010951//negative regulation of endopeptidase activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045616//regulation of keratinocyte differentiation;GO:0061045//negative regulation of wound healing;GO:0072675//osteoclast fusion	--
ENSG00000156564	0.046	0.091	0.021	0.144	0.09	0	3	6	1	7	5	0	LRFN2	leucine rich repeat and fibronectin type III domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21226]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0050804//modulation of chemical synaptic transmission;GO:0099175//regulation of postsynapse organization	--
ENSG00000156574	0.047	0	0.032	0	0.062	0	2	0	1	0	2	0	NODAL	nodal growth differentiation factor [Source:HGNC Symbol;Acc:HGNC:7865]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04666;K04666;K04666	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0016015//morphogen activity;GO:0048018//receptor ligand activity;GO:0070698//type I activin receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001702//gastrulation with mouth forming second;GO:0001707//mesoderm formation;GO:0001829//trophectodermal cell differentiation;GO:0001831//trophectodermal cellular morphogenesis;GO:0001842//neural fold formation;GO:0001889//liver development;GO:0001890//placenta development;GO:0001892//embryonic placenta development;GO:0001893//maternal placenta development;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0002085//inhibition of neuroepithelial cell differentiation;GO:0007165//signal transduction;GO:0007368//determination of left/right symmetry;GO:0007369//gastrulation;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007492//endoderm development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0009966//regulation of signal transduction;GO:0010085//polarity specification of proximal/distal axis;GO:0010470//regulation of gastrulation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010721//negative regulation of cell development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016477//cell migration;GO:0019827//stem cell population maintenance;GO:0022409//positive regulation of cell-cell adhesion;GO:0030324//lung development;GO:0030509//BMP signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0033505//floor plate morphogenesis;GO:0035050//embryonic heart tube development;GO:0035987//endodermal cell differentiation;GO:0038092//nodal signaling pathway;GO:0042074//cell migration involved in gastrulation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048327//axial mesodermal cell fate specification;GO:0048382//mesendoderm development;GO:0048546//digestive tract morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048729//tissue morphogenesis;GO:0048859//formation of anatomical boundary;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0055123//digestive system development;GO:0060136//embryonic process involved in female pregnancy;GO:0060137//maternal process involved in parturition;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060395//SMAD protein signal transduction;GO:0060460//left lung morphogenesis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060802//epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090009//primitive streak formation;GO:0090010//transforming growth factor beta receptor signaling pathway involved in primitive streak formation;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:1901164//negative regulation of trophoblast cell migration;GO:1901383//negative regulation of chorionic trophoblast cell proliferation;GO:2000036//regulation of stem cell population maintenance	--
ENSG00000156575	0	0	0	0	0	0	0	0	0	0	0	0	PRG3	"proteoglycan 3, pro eosinophil major basic protein 2 [Source:HGNC Symbol;Acc:HGNC:9363]"	-	-	-	-	GO:0005576//extracellular region;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:1904724//tertiary granule lumen	GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0030246//carbohydrate binding	GO:0001694//histamine biosynthetic process;GO:0006955//immune response;GO:0017148//negative regulation of translation;GO:0019370//leukotriene biosynthetic process;GO:0032757//positive regulation of interleukin-8 production;GO:0042119//neutrophil activation;GO:0042554//superoxide anion generation;GO:0045575//basophil activation	--
ENSG00000156587	34.676	38.155	37.498	35.432	36.783	38.767	889	988	711	674	801	726	UBE2L6	ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K04553;K04553;K04553	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042296//ISG15 transferase activity;GO:0043130//ubiquitin binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0032020//ISG15-protein conjugation;GO:0032446//protein modification by small protein conjugation	--
ENSG00000156599	24.969	26.739	26.403	27.178	28.937	28.624	2266	2418	1765	1815	2192	1881	ZDHHC5	zinc finger DHHC-type palmitoyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:18472]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045335//phagocytic vesicle	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0018345//protein palmitoylation;GO:0062208//positive regulation of pattern recognition receptor signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1905171//positive regulation of protein localization to phagocytic vesicle	--
ENSG00000156603	14.585	12.665	11	12.733	11.195	12.047	333	291	186	215	216	201	MED19	mediator complex subunit 19 [Source:HGNC Symbol;Acc:HGNC:29600]	-	-	-	-	GO:0005634//nucleus;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000156639	51.211	49.745	49.999	48.485	49.558	49.366	3312	3234	2360	2334	2720	2320	ZFAND3	zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000156642	77.947	81.352	75.974	73.332	80.692	92.422	2376	2456	1800	1756	2006	1972	NPTN	neuroplastin [Source:HGNC Symbol;Acc:HGNC:17867]	-	-	-	-	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0060077//inhibitory synapse;GO:0097060//synaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099059//integral component of presynaptic active zone membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0050839//cell adhesion molecule binding;GO:0098632//cell-cell adhesion mediator activity	"GO:0001818//negative regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008542//visual learning;GO:0010976//positive regulation of neuron projection development;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0060291//long-term synaptic potentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070593//dendrite self-avoidance;GO:0099557//trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1902683//regulation of receptor localization to synapse;GO:1903829//positive regulation of cellular protein localization;GO:1904861//excitatory synapse assembly"	--
ENSG00000156650	5.356	3.899	3.86	2.221	3.11	2.951	767	600	386	259	403	330	KAT6B	lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0043966//histone H3 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050793//regulation of developmental process;GO:1903706//regulation of hemopoiesis"	--
ENSG00000156671	6.634	5.029	5.641	4.355	5.046	7.29	940	718	574	459	604	734	SAMD8	sterile alpha motif domain containing 8 [Source:HGNC Symbol;Acc:HGNC:26320]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0002950//ceramide phosphoethanolamine synthase activity;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0033188//sphingomyelin synthase activity;GO:0047493//ceramide cholinephosphotransferase activity"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:1905373//ceramide phosphoethanolamine biosynthetic process;GO:2000303//regulation of ceramide biosynthetic process	--
ENSG00000156675	36.293	35.285	36.544	32.39	33.817	35.02	4885	4854	3820	3350	3930	3543	RAB11FIP1	RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12484	GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	GO:0031267//small GTPase binding	GO:0015031//protein transport;GO:0045055//regulated exocytosis;GO:0070164//negative regulation of adiponectin secretion	--
ENSG00000156687	5.214	4.449	4.804	3.194	3.456	3.499	875	745	577	382	498	424	UNC5D	unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07521	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005042//netrin receptor activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0021859//pyramidal neuron differentiation;GO:0038007//netrin-activated signaling pathway;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:2001222//regulation of neuron migration	--
ENSG00000156689	0.032	0	0.044	0	0.038	0	1	0	1	0	1	0	GLYATL2	glycine-N-acyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:24178]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum	GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047961//glycine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0042758//long-chain fatty acid catabolic process;GO:0051793//medium-chain fatty acid catabolic process;GO:1903965//monounsaturated fatty acid catabolic process	--
ENSG00000156697	7.809	8.753	7.832	6.335	6.641	7.083	405.81	456.45	299.89	244	291	268	UTP14A	UTP14A small subunit processome component [Source:HGNC Symbol;Acc:HGNC:10665]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14567	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000156709	21.794	23.858	24.144	25.878	23.608	29.139	1015	1115	837	887	929	985	AIFM1	apoptosis inducing factor mitochondria associated 1 [Source:HGNC Symbol;Acc:HGNC:8768]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04217//Necroptosis;ko04210//Apoptosis	K04727;K04727	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0003677//DNA binding;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0016174//NAD(P)H oxidase H2O2-forming activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046983//protein dimerization activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0002931//response to ischemia;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009636//response to toxic substance;GO:0010942//positive regulation of cell death;GO:0012501//programmed cell death;GO:0030182//neuron differentiation;GO:0030261//chromosome condensation;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0043065//positive regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0045041//protein import into mitochondrial intermembrane space;GO:0051402//neuron apoptotic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070301//cellular response to hydrogen peroxide;GO:0071392//cellular response to estradiol stimulus;GO:0071732//cellular response to nitric oxide;GO:0090650//cellular response to oxygen-glucose deprivation;GO:1902065//response to L-glutamate;GO:1902510//regulation of apoptotic DNA fragmentation;GO:1904045//cellular response to aldosterone	--
ENSG00000156711	0.581	0.632	0.457	0.474	0.724	0.483	76	83	44	46	66	46	MAPK13	mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Nervous system;Circulatory system;Infectious disease: parasitic;Cellular community - eukaryotes;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Nervous system;Signal transduction;Endocrine system;Immune system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Cancer: overview;Immune system;Endocrine system;Infectious disease: bacterial;Endocrine system;Immune system;Infectious disease: bacterial;Signal transduction	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04114//Oocyte meiosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway"	K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006970//response to osmotic stress;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032755//positive regulation of interleukin-6 production;GO:0034644//cellular response to UV;GO:0035556//intracellular signal transduction;GO:0050729//positive regulation of inflammatory response;GO:0051403//stress-activated MAPK cascade;GO:0070301//cellular response to hydrogen peroxide;GO:0071347//cellular response to interleukin-1;GO:0072709//cellular response to sorbitol;GO:0072740//cellular response to anisomycin;GO:1903936//cellular response to sodium arsenite	--
ENSG00000156735	7.292	6.657	7.754	4.185	5.084	6.297	529	504	413	252	320	365	BAG4	BAG cochaperone 4 [Source:HGNC Symbol;Acc:HGNC:940]	Environmental Information Processing	Signal transduction	ko04668//TNF signaling pathway	K09558	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0051087//chaperone binding	"GO:0006457//protein folding;GO:0010763//positive regulation of fibroblast migration;GO:0030838//positive regulation of actin filament polymerization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0045785//positive regulation of cell adhesion;GO:0050821//protein stabilization;GO:0051496//positive regulation of stress fiber assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072659//protein localization to plasma membrane;GO:0097178//ruffle assembly;GO:1903215//negative regulation of protein targeting to mitochondrion;GO:2001145//negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity"	--
ENSG00000156738	0	0	0	0	0.023	0	0	0	0	0	1	0	MS4A1	membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06466	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044853//plasma membrane raft;GO:0070062//extracellular exosome	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0019865//immunoglobulin binding;GO:0023026//MHC class II protein complex binding;GO:0042802//identical protein binding	GO:0002115//store-operated calcium entry;GO:0006959//humoral immune response;GO:0007166//cell surface receptor signaling pathway;GO:0009617//response to bacterium;GO:0030183//B cell differentiation;GO:0042100//B cell proliferation;GO:0042113//B cell activation;GO:0050853//B cell receptor signaling pathway;GO:0051262//protein tetramerization;GO:1902656//calcium ion import into cytosol	--
ENSG00000156787	3.041	2.305	3.203	2.772	1.756	2.922	95.07	84.98	55.55	48.97	56.54	57.65	TBC1D31	TBC1 domain family member 31 [Source:HGNC Symbol;Acc:HGNC:30888]	-	-	-	-	GO:0005813//centrosome	GO:0005515//protein binding	-	--
ENSG00000156795	6.506	6.691	5.071	8.005	6.57	5.997	173	164	102	167	145	109	NTAQ1	N-terminal glutamine amidase 1 [Source:HGNC Symbol;Acc:HGNC:25490]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0008418//protein-N-terminal asparagine amidohydrolase activity;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0070773//protein-N-terminal glutamine amidohydrolase activity"	GO:0006464//cellular protein modification process	--
ENSG00000156802	2.286	1.565	1.365	0.81	1.109	0.92	263	181	115	69	95	77	ATAD2	ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000156804	27.939	21.902	21.561	19.891	19.978	19.354	2707	2479	1756	1497	1718	1374	FBXO32	F-box protein 32 [Source:HGNC Symbol;Acc:HGNC:16731]	Environmental Information Processing	Signal transduction	ko04068//FoxO signaling pathway	K10305	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0030018//Z disc	GO:0005515//protein binding	GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination;GO:0071549//cellular response to dexamethasone stimulus	--
ENSG00000156831	14.78	12.031	13.366	13.002	12.153	12.823	328	269	212	206	225	202	NSMCE2	"NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase [Source:HGNC Symbol;Acc:HGNC:26513]"	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0016605//PML body;GO:0030915//Smc5-Smc6 complex"	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0046872//metal ion binding;GO:0061665//SUMO ligase activity	GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0016925//protein sumoylation;GO:0032204//regulation of telomere maintenance;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0090398//cellular senescence	--
ENSG00000156853	5.991	6.338	6.441	6.624	7.107	7.433	442	470	351	362	443	399	ZNF689	zinc finger protein 689 [Source:HGNC Symbol;Acc:HGNC:25173]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035914//skeletal muscle cell differentiation"	zf-C2H2
ENSG00000156858	10.591	10.57	10.248	11.968	11.434	13.347	404	391	320	330	363	361	PRR14	proline rich 14 [Source:HGNC Symbol;Acc:HGNC:28458]	-	-	-	-	GO:0005634//nucleus;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0005515//protein binding	GO:0007517//muscle organ development	--
ENSG00000156860	16.487	19.415	17.98	18.229	18.976	17.911	1409	1595	1136	1194	1386	1172	FBRS	fibrosin [Source:HGNC Symbol;Acc:HGNC:20442]	-	-	-	-	-	-	-	--
ENSG00000156869	1.192	1.42	1.346	1.218	0.861	1.342	128	138	121	92	85	88	FRRS1	ferric chelate reductase 1 [Source:HGNC Symbol;Acc:HGNC:27622]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016491//oxidoreductase activity;GO:0016722//oxidoreductase activity, acting on metal ions;GO:0046872//metal ion binding"	GO:0006879//cellular iron ion homeostasis	--
ENSG00000156873	10.243	9.86	10.834	11.279	11.299	10.877	339.99	332	266.28	280.86	316.29	260.4	PHKG2	phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04910//Insulin signaling pathway;ko04922//Glucagon signaling pathway	K00871;K00871;K00871	GO:0005829//cytosol;GO:0005964//phosphorylase kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004689//phosphorylase kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0050321//tau-protein kinase activity	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0045819//positive regulation of glycogen catabolic process	--
ENSG00000156875	27.195	26.327	27.848	28.99	26.086	30.811	1567.6	1525.34	1185.54	1237.81	1270.36	1292.21	MFSD14A	major facilitator superfamily domain containing 14A [Source:HGNC Symbol;Acc:HGNC:23363]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000156876	1.303	0.81	0.628	0.541	0.593	0.93	104	65	37	32	40	54	SASS6	SAS-6 centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:25403]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0098536//deuterosome;GO:0120099//procentriole replication complex	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0046601//positive regulation of centriole replication;GO:0051298//centrosome duplication;GO:0060236//regulation of mitotic spindle organization;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1905832//positive regulation of spindle assembly	--
ENSG00000156885	0	0	0	0	0	0	0	0	0	0	0	0	COX6A2	cytochrome c oxidase subunit 6A2 [Source:HGNC Symbol;Acc:HGNC:2279]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266;K02266	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004129//cytochrome-c oxidase activity;GO:0016491//oxidoreductase activity;GO:0030234//enzyme regulator activity	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0050790//regulation of catalytic activity;GO:1902600//proton transmembrane transport"	--
ENSG00000156886	0	0	0	0	0	0	0	0	0	0	0	0	ITGAD	integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K06594	GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0046872//metal ion binding	GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000156920	0	0.005	0	0	0	0	0	1	0	0	0	0	ADGRG4	adhesion G protein-coupled receptor G4 [Source:HGNC Symbol;Acc:HGNC:18992]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000156925	0.267	0.229	0.556	0.328	0.3	0.375	18	17	28	14	21	16	ZIC3	Zic family member 3 [Source:HGNC Symbol;Acc:HGNC:12874]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K18487	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001947//heart looping;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0009952//anterior/posterior pattern specification;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0035469//determination of pancreatic left/right asymmetry;GO:0035545//determination of left/right asymmetry in nervous system;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry"	zf-C2H2
ENSG00000156928	7.837	7.542	8.284	10.289	8.69	10.305	472.23	456.76	368.66	459.21	442.37	451.81	MALSU1	mitochondrial assembly of ribosomal large subunit 1 [Source:HGNC Symbol;Acc:HGNC:21721]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit;GO:0005829//cytosol	GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding	GO:0017148//negative regulation of translation;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0070130//negative regulation of mitochondrial translation;GO:0090071//negative regulation of ribosome biogenesis	--
ENSG00000156931	10.188	8.083	7.315	6.309	6.763	8.185	853	772	544	422	504	520	VPS8	VPS8 subunit of CORVET complex [Source:HGNC Symbol;Acc:HGNC:29122]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0033263//CORVET complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly	--
ENSG00000156958	8.335	8.024	10.276	6.953	6.867	8.78	328.78	274.97	248.29	187.21	241.28	246.3	GALK2	galactokinase 2 [Source:HGNC Symbol;Acc:HGNC:4119]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K18674;K18674	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0004335//galactokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0033858//N-acetylgalactosamine kinase activity"	GO:0005975//carbohydrate metabolic process;GO:0006012//galactose metabolic process;GO:0006793//phosphorus metabolic process;GO:0016310//phosphorylation;GO:0044238//primary metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0071704//organic substance metabolic process	--
ENSG00000156959	0.01	0.01	0	0	0	0	1	1	0	0	0	0	LHFPL4	LHFPL tetraspan subfamily member 4 [Source:HGNC Symbol;Acc:HGNC:29568]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse	GO:0005515//protein binding;GO:0050811//GABA receptor binding	GO:0007605//sensory perception of sound;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:1905702//regulation of inhibitory synapse assembly	--
ENSG00000156966	2.656	3.334	2.822	1.931	2.193	2.584	195	246	153	105	136	138	B3GNT7	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:18811]"	Metabolism	Glycan biosynthesis and metabolism	ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K09664	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity"	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0030311//poly-N-acetyllactosamine biosynthetic process	--
ENSG00000156968	1.62	2.459	1.766	1.295	2.083	1.344	197	272	111	117	215	119	MPV17L	MPV17 mitochondrial inner membrane protein like [Source:HGNC Symbol;Acc:HGNC:26827]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13349	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function	GO:0010730//negative regulation of hydrogen peroxide biosynthetic process;GO:0072593//reactive oxygen species metabolic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	--
ENSG00000156970	1.984	2.066	2.117	1.437	1.12	1.824	151	158	119	81	72	101	BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149]	Human Diseases;Cellular Processes	Infectious disease: viral;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04110//Cell cycle	K06637;K06637	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005680//anaphase-promoting complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0033597//mitotic checkpoint complex;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0016310//phosphorylation;GO:0051301//cell division;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051754//meiotic sister chromatid cohesion, centromeric"	--
ENSG00000156973	13.362	14.821	15.588	15.365	13.26	16.381	311	336	258	253	255	272	PDE6D	phosphodiesterase 6D [Source:HGNC Symbol;Acc:HGNC:8788]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13758;K13758	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007601//visual perception;GO:0043086//negative regulation of catalytic activity;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus	--
ENSG00000156976	246.664	235.311	246.343	222.075	206.642	241.731	9557	9155	7071	6418	6777	6822	EIF4A2	eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]	-	-	-	-	GO:0005829//cytosol;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003743//translation initiation factor activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:1900260//negative regulation of RNA-directed 5'-3' RNA polymerase activity	--
ENSG00000156983	5.06	5.546	5.384	5.723	6.543	6.534	479	533	369	411	532	443	BRPF1	bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0010698//acetyltransferase activator activity;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0043972//histone H3-K23 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity;GO:0050793//regulation of developmental process;GO:1903706//regulation of hemopoiesis"	--
ENSG00000156990	12.326	13.389	13.337	13.207	12.068	15.512	298	330	242	240	250	272	RPUSD3	RNA pseudouridine synthase D3 [Source:HGNC Symbol;Acc:HGNC:28437]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity	GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0006397//mRNA processing;GO:0009451//RNA modification;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000157005	2.78	4.425	4.087	0.214	1.504	0.327	35	56	38	2	16	3	SST	somatostatin [Source:HGNC Symbol;Acc:HGNC:11329]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Digestive system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04971//Gastric acid secretion"	K05237;K05237;K05237;K05237	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006972//hyperosmotic response;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007584//response to nutrient;GO:0007586//digestion;GO:0008285//negative regulation of cell population proliferation;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0009408//response to heat;GO:0009410//response to xenobiotic stimulus;GO:0010243//response to organonitrogen compound;GO:0010447//response to acidic pH;GO:0030334//regulation of cell migration;GO:0043200//response to amino acid;GO:0048545//response to steroid hormone	--
ENSG00000157014	14.798	14.175	14.803	12.881	15.366	13.741	1307.47	1326.57	1005.05	991.92	1081.82	1025.06	TATDN2	TatD DNase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28988]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0004518//nuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000157017	0	0.037	0	0	0.043	0	0	1	0	0	1	0	GHRL	ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05254;K05254;K05254	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0030424//axon;GO:0034774//secretory granule lumen;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0016608//growth hormone-releasing hormone activity;GO:0030296//protein tyrosine kinase activator activity;GO:0031768//ghrelin receptor binding	"GO:0001696//gastric acid secretion;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006006//glucose metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008154//actin polymerization or depolymerization;GO:0008343//adult feeding behavior;GO:0009725//response to hormone;GO:0009755//hormone-mediated signaling pathway;GO:0016358//dendrite development;GO:0016525//negative regulation of angiogenesis;GO:0030252//growth hormone secretion;GO:0031667//response to nutrient levels;GO:0032024//positive regulation of insulin secretion;GO:0032095//regulation of response to food;GO:0032097//positive regulation of response to food;GO:0032100//positive regulation of appetite;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035483//gastric emptying;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0040010//positive regulation of growth rate;GO:0040013//negative regulation of locomotion;GO:0040018//positive regulation of multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0042322//negative regulation of circadian sleep/wake cycle, REM sleep;GO:0043066//negative regulation of apoptotic process;GO:0043400//cortisol secretion;GO:0043410//positive regulation of MAPK cascade;GO:0043627//response to estrogen;GO:0045927//positive regulation of growth;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:0046676//negative regulation of insulin secretion;GO:0046697//decidualization;GO:0050728//negative regulation of inflammatory response;GO:0051216//cartilage development;GO:0051461//positive regulation of corticotropin secretion;GO:0051464//positive regulation of cortisol secretion;GO:0051602//response to electrical stimulus;GO:0051965//positive regulation of synapse assembly;GO:0051969//regulation of transmission of nerve impulse;GO:0060079//excitatory postsynaptic potential;GO:0060124//positive regulation of growth hormone secretion;GO:0060399//positive regulation of growth hormone receptor signaling pathway;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:0099175//regulation of postsynapse organization;GO:0120058//positive regulation of small intestinal transit;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1903012//positive regulation of bone development;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904000//positive regulation of eating behavior;GO:1904179//positive regulation of adipose tissue development;GO:1904306//positive regulation of gastro-intestinal system smooth muscle contraction;GO:1904346//positive regulation of gastric mucosal blood circulation;GO:1904349//positive regulation of small intestine smooth muscle contraction;GO:1905333//regulation of gastric motility;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000253//positive regulation of feeding behavior"	--
ENSG00000157020	65.202	70.244	63.927	64.635	59.724	65.164	1834	1972	1345	1284	1402	1321	SEC13	"SEC13 homolog, nuclear pore and COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10697]"	Human Diseases;Genetic Information Processing;Environmental Information Processing;Genetic Information Processing	"Neurodegenerative disease;Folding, sorting and degradation;Signal transduction;Translation"	ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04150//mTOR signaling pathway;ko03013//Nucleocytoplasmic transport	K14004;K14004;K14004;K14004	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031080//nuclear pore outer ring;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0061700//GATOR2 complex;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032008//positive regulation of TOR signaling;GO:0032527//protein exit from endoplasmic reticulum;GO:0051028//mRNA transport;GO:0090110//COPII-coated vesicle cargo loading;GO:0090114//COPII-coated vesicle budding;GO:1904262//negative regulation of TORC1 signaling;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000157036	3.876	3.225	3.453	4.494	4.223	5.422	204	176	150	163	195	187	EXOG	exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006309//apoptotic DNA fragmentation;GO:0008150//biological_process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000157045	12.219	12.139	13.258	10.237	8.312	10.824	296.14	295.73	224.32	171.7	166.94	183.08	NTAN1	N-terminal asparagine amidase [Source:HGNC Symbol;Acc:HGNC:29909]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008418//protein-N-terminal asparagine amidohydrolase activity;GO:0016787//hydrolase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007613//memory;GO:0008344//adult locomotory behavior	--
ENSG00000157060	0	0	0	0	0	0	0	0	0	0	0	0	SHCBP1L	SHC binding and spindle associated 1 like [Source:HGNC Symbol;Acc:HGNC:16788]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0072687//meiotic spindle	GO:0005515//protein binding	GO:0007112//male meiosis cytokinesis;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:2001252//positive regulation of chromosome organization	--
ENSG00000157064	0.186	0.115	0.168	0.179	0.136	0.11	21	13	14	15	13	9	NMNAT2	nicotinamide nucleotide adenylyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16789]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K06210;K06210	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0030424//axon;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0003824//catalytic activity;GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0009058//biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process	--
ENSG00000157077	12.852	11.498	11.602	9.988	10.345	11.557	1392	1238	921	811	952	914	ZFYVE9	zinc finger FYVE-type containing 9 [Source:HGNC Symbol;Acc:HGNC:6775]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Signal transduction	ko04144//Endocytosis;ko04350//TGF-beta signaling pathway	K04679;K04679	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016197//endosomal transport	--
ENSG00000157087	19.098	20.27	17.019	15.043	15.604	15.973	2362	2433	1518	1379	1627	1502	ATP2B2	ATPase plasma membrane Ca2+ transporting 2 [Source:HGNC Symbol;Acc:HGNC:815]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Circulatory system;Digestive system;Endocrine system;Digestive system;Digestive system;Excretory system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04972//Pancreatic secretion;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850;K05850	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032591//dendritic spine membrane;GO:0032809//neuronal cell body membrane;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0035254//glutamate receptor binding;GO:0046872//metal ion binding;GO:1905056//P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration;GO:1905059//P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GO:0003407//neural retina development;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007420//brain development;GO:0007605//sensory perception of sound;GO:0030182//neuron differentiation;GO:0034220//ion transmembrane transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0070588//calcium ion transmembrane transport;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1903779//regulation of cardiac conduction	--
ENSG00000157093	0	0	0	0	0	0	0	0	0	0	0	0	LYZL4	lysozyme like 4 [Source:HGNC Symbol;Acc:HGNC:28387]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0003796//lysozyme activity	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0009566//fertilization	--
ENSG00000157103	0	0	0	0	0	0	0	0	0	0	0	0	SLC6A1	solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04727//GABAergic synapse;ko04721//Synaptic vesicle cycle	K05034;K05034	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0098793//presynapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005515//protein binding;GO:0015185//gamma-aminobutyric acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015378//sodium:chloride symporter activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0007612//learning;GO:0007613//memory;GO:0008306//associative learning;GO:0009636//response to toxic substance;GO:0009744//response to sucrose;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010243//response to organonitrogen compound;GO:0010288//response to lead ion;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0014070//response to organic cyclic compound;GO:0014074//response to purine-containing compound;GO:0015812//gamma-aminobutyric acid transport;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0032355//response to estradiol;GO:0035725//sodium ion transmembrane transport;GO:0042220//response to cocaine;GO:0050808//synapse organization;GO:0051592//response to calcium ion;GO:0051936//gamma-aminobutyric acid reuptake;GO:0051939//gamma-aminobutyric acid import;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0098658//inorganic anion import across plasma membrane;GO:0098719//sodium ion import across plasma membrane;GO:0098810//neurotransmitter reuptake;GO:0150104//transport across blood-brain barrier;GO:1902476//chloride transmembrane transport"	--
ENSG00000157106	14.475	10.539	15.834	11.821	13.319	14.406	2512.88	1905.94	1667.65	1269.15	1713.77	1548.02	SMG1	SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K08873	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0033391//chromatoid body	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042162//telomeric DNA binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006281//DNA repair;GO:0006406//mRNA export from nucleus;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031929//TOR signaling;GO:0032204//regulation of telomere maintenance;GO:0046777//protein autophosphorylation;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0060255//regulation of macromolecule metabolic process;GO:0080135//regulation of cellular response to stress;GO:2001020//regulation of response to DNA damage stimulus"	--
ENSG00000157107	5.516	2.983	3.29	2.804	4.012	3.443	518	306	248	199	288	245	FCHO2	FCH and mu domain containing endocytic adaptor 2 [Source:HGNC Symbol;Acc:HGNC:25180]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0098835//presynaptic endocytic zone membrane	"GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding"	GO:0006897//endocytosis;GO:0010324//membrane invagination;GO:0048268//clathrin coat assembly;GO:0048488//synaptic vesicle endocytosis;GO:0072583//clathrin-dependent endocytosis;GO:0072659//protein localization to plasma membrane	--
ENSG00000157110	65.928	64.098	66.06	67.533	64.834	70.378	2174	2200	1580	1675	1852	1716	RBPMS	"RNA binding protein, mRNA processing factor [Source:HGNC Symbol;Acc:HGNC:19097]"	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0003676//nucleic acid binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0042803//protein homodimerization activity	"GO:0006396//RNA processing;GO:0006979//response to oxidative stress;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060391//positive regulation of SMAD protein signal transduction"	--
ENSG00000157111	0.271	0.27	0.21	0.104	0	0.533	7	7	4	2	0	10	TMEM171	transmembrane protein 171 [Source:HGNC Symbol;Acc:HGNC:27031]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000157119	0	0	0	0	0	0.053	0	0	0	0	0	2	KLHL40	kelch like family member 40 [Source:HGNC Symbol;Acc:HGNC:30372]	-	-	-	-	GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031672//A band;GO:0031674//I band	GO:0005515//protein binding	GO:0031397//negative regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048741//skeletal muscle fiber development;GO:0098528//skeletal muscle fiber differentiation	--
ENSG00000157131	0	0	0	0	0	0	0	0	0	0	0	0	C8A	complement C8 alpha chain [Source:HGNC Symbol;Acc:HGNC:1352]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: parasitic;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05146//Amoebiasis;ko04610//Complement and coagulation cascades	K03997;K03997;K03997;K03997;K03997	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001848//complement binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	"GO:0002376//immune system process;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response"	--
ENSG00000157150	0.04	0.402	0.055	0.164	0.191	0.277	1	10	1	3	4	5	TIMP4	TIMP metallopeptidase inhibitor 4 [Source:HGNC Symbol;Acc:HGNC:11823]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030017//sarcomere;GO:0031012//extracellular matrix	GO:0002020//protease binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0046872//metal ion binding	GO:0007219//Notch signaling pathway;GO:0007417//central nervous system development;GO:0008150//biological_process;GO:0009410//response to xenobiotic stimulus;GO:0009725//response to hormone;GO:0010033//response to organic substance;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0032496//response to lipopolysaccharide;GO:0034097//response to cytokine;GO:0042698//ovulation cycle;GO:0043434//response to peptide hormone;GO:0051045//negative regulation of membrane protein ectodomain proteolysis	--
ENSG00000157152	0.968	1.138	1.022	1.535	1.278	1.166	71	84	56	84	80	62	SYN2	synapsin II [Source:HGNC Symbol;Acc:HGNC:11495]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0005524//ATP binding;GO:0042802//identical protein binding	GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0017156//calcium-ion regulated exocytosis;GO:0097091//synaptic vesicle clustering;GO:0099504//synaptic vesicle cycle	--
ENSG00000157168	1.497	1.797	1.434	1.684	1.653	1.56	82	99	58	61	73	69	NRG1	neuregulin 1 [Source:HGNC Symbol;Acc:HGNC:7997]	Human Diseases;Environmental Information Processing;Human Diseases	Neurodegenerative disease;Signal transduction;Drug resistance: antineoplastic	ko05014//Amyotrophic lateral sclerosis;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K05455;K05455;K05455	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0003712//transcription coregulator activity;GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030296//protein tyrosine kinase activator activity;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding;GO:0043125//ErbB-3 class receptor binding;GO:0045499//chemorepellent activity;GO:0048018//receptor ligand activity	"GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007399//nervous system development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014032//neural crest cell development;GO:0030154//cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030879//mammary gland development;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032148//activation of protein kinase B activity;GO:0035556//intracellular signal transduction;GO:0038127//ERBB signaling pathway;GO:0038129//ERBB3 signaling pathway;GO:0038130//ERBB4 signaling pathway;GO:0042060//wound healing;GO:0043624//cellular protein complex disassembly;GO:0045785//positive regulation of cell adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048513//animal organ development;GO:0051048//negative regulation of secretion;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0060956//endocardial cell differentiation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:0099560//synaptic membrane adhesion;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000157181	3.799	2.672	2.751	2.195	2.489	2.449	276	195	161	117	165	136	ODR4	odr-4 GPCR localization factor homolog [Source:HGNC Symbol;Acc:HGNC:24299]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0008104//protein localization	--
ENSG00000157184	13.443	13.622	17.316	17.273	17.662	17.719	748	764	714	709	832	719	CPT2	carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330]	Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Metabolism	Environmental adaptation;Cardiovascular disease;Endocrine system;Global and overview maps;Lipid metabolism	ko04714//Thermogenesis;ko05415//Diabetic cardiomyopathy;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K08766;K08766;K08766;K08766;K08766	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0004095//carnitine O-palmitoyltransferase activity;GO:0005515//protein binding;GO:0008458//carnitine O-octanoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0001701//in utero embryonic development;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006853//carnitine shuttle;GO:0009437//carnitine metabolic process;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000157191	20.45	17.737	18.375	20.047	21.439	20.907	786	730	515	618	728	632	NECAP2	NECAP endocytosis associated 2 [Source:HGNC Symbol;Acc:HGNC:25528]	-	-	-	-	GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030125//clathrin vesicle coat;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	-	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000157193	26.6	23.366	26.423	28.4	30.311	34.636	3029	2654	2218	2365	2850	2800	LRP8	LDL receptor related protein 8 [Source:HGNC Symbol;Acc:HGNC:6700]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005041//low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008035//high-density lipoprotein particle binding;GO:0019894//kinesin binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0034185//apolipoprotein binding;GO:0038024//cargo receptor activity;GO:0038025//reelin receptor activity;GO:0047485//protein N-terminus binding;GO:0048306//calcium-dependent protein binding	GO:0001523//retinoid metabolic process;GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0009410//response to xenobiotic stimulus;GO:0019221//cytokine-mediated signaling pathway;GO:0021517//ventral spinal cord development;GO:0021541//ammon gyrus development;GO:0021766//hippocampus development;GO:0021819//layer formation in cerebral cortex;GO:0021987//cerebral cortex development;GO:0032793//positive regulation of CREB transcription factor activity;GO:0038026//reelin-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0045088//regulation of innate immune response;GO:0045860//positive regulation of protein kinase activity;GO:0048813//dendrite morphogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050804//modulation of chemical synaptic transmission;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0071363//cellular response to growth factor stimulus;GO:0071397//cellular response to cholesterol;GO:1900006//positive regulation of dendrite development	--
ENSG00000157211	0	0	0	0	0	0	0	0	0	0	0	0	CDCP2	CUB domain containing protein 2 [Source:HGNC Symbol;Acc:HGNC:27297]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	-	-	--
ENSG00000157212	3.45	3.415	3.785	2.42	3.122	3.125	266	265	197	138	203	175	PAXIP1	PAX interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8624]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016363//nuclear matrix;GO:0035097//histone methyltransferase complex;GO:0043229//intracellular organelle;GO:0044666//MLL3/4 complex	GO:0005515//protein binding	"GO:0000416//positive regulation of histone H3-K36 methylation;GO:0001570//vasculogenesis;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0031398//positive regulation of protein ubiquitination;GO:0035066//positive regulation of histone acetylation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043542//endothelial cell migration;GO:0045830//positive regulation of isotype switching;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0051568//histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060612//adipose tissue development;GO:0060717//chorion development;GO:1902749//regulation of cell cycle G2/M phase transition;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000157214	0.347	0.443	0.227	0.216	0.709	0.368	31	33	23	11	25	28	STEAP2	STEAP2 metalloreductase [Source:HGNC Symbol;Acc:HGNC:17885]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14738	GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0030173//integral component of Golgi membrane	GO:0008823//cupric reductase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0052851//ferric-chelate reductase (NADPH) activity	GO:0006811//ion transport;GO:0006893//Golgi to plasma membrane transport;GO:0006897//endocytosis;GO:0009725//response to hormone;GO:0015677//copper ion import;GO:0045055//regulated exocytosis;GO:0055072//iron ion homeostasis;GO:0098705//copper ion import across plasma membrane;GO:0098711//iron ion import across plasma membrane	--
ENSG00000157216	23.741	22.603	14.694	23.415	26.779	21.679	1069	1063	648	814	1082	837	SSBP3	single stranded DNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:15674]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0002244//hematopoietic progenitor cell differentiation;GO:0008284//positive regulation of cell population proliferation;GO:0021501//prechordal plate formation;GO:0021547//midbrain-hindbrain boundary initiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048382//mesendoderm development;GO:0060322//head development;GO:0060323//head morphogenesis;GO:0065003//protein-containing complex assembly;GO:2000744//positive regulation of anterior head development"	--
ENSG00000157219	0	0	0	0	0	0	0	0	0	0	0	0	HTR5A	5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04726//Serotonergic synapse	K04161;K04161;K04161	GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0099060//integral component of postsynaptic specialization membrane	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0021766//hippocampus development;GO:0032355//response to estradiol;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000157224	15.584	13.946	15.826	14.505	14.647	16.443	1111	1011	863	794	880	883	CLDN12	claudin 12 [Source:HGNC Symbol;Acc:HGNC:2034]	-	-	-	-	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0070160//tight junction;GO:0071944//cell periphery	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0035633//maintenance of blood-brain barrier	--
ENSG00000157227	343.085	356.527	358.13	405.152	411.774	441.449	20535	21739	16348	18492	20944	19445	MMP14	matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	"ko04668//TNF signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04912//GnRH signaling pathway"	K07763;K07763;K07763	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0044354//macropinosome;GO:0045111//intermediate filament cytoskeleton	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001666//response to hypoxia;GO:0001935//endothelial cell proliferation;GO:0001958//endochondral ossification;GO:0006508//proteolysis;GO:0006979//response to oxidative stress;GO:0008584//male gonad development;GO:0009612//response to mechanical stimulus;GO:0009725//response to hormone;GO:0010831//positive regulation of myotube differentiation;GO:0010954//positive regulation of protein processing;GO:0014070//response to organic cyclic compound;GO:0016477//cell migration;GO:0016485//protein processing;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030307//positive regulation of cell growth;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0030574//collagen catabolic process;GO:0031638//zymogen activation;GO:0035987//endodermal cell differentiation;GO:0035988//chondrocyte proliferation;GO:0043615//astrocyte cell migration;GO:0043627//response to estrogen;GO:0045579//positive regulation of B cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048771//tissue remodeling;GO:0048870//cell motility;GO:0051895//negative regulation of focal adhesion assembly;GO:0060322//head development;GO:0060348//bone development;GO:0097094//craniofacial suture morphogenesis;GO:1903076//regulation of protein localization to plasma membrane;GO:1905523//positive regulation of macrophage migration;GO:1990834//response to odorant	--
ENSG00000157240	11.007	11	12.726	13.944	13.749	15.32	1574	1581	1344	1477	1661	1594	FZD1	frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432;K02432	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990909//Wnt signalosome	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity	"GO:0001934//positive regulation of protein phosphorylation;GO:0003149//membranous septum morphogenesis;GO:0003150//muscular septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009410//response to xenobiotic stimulus;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030514//negative regulation of BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0035425//autocrine signaling;GO:0036520//astrocyte-dopaminergic neuron signaling;GO:0044338//canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0044339//canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060022//hard palate development;GO:0060070//canonical Wnt signaling pathway;GO:0060412//ventricular septum morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0099054//presynapse assembly;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1905606//regulation of presynapse assembly"	--
ENSG00000157259	5.7	5.357	4.897	5.081	5.021	6.29	503	453	319	340	402.18	426.29	GATAD1	GATA zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29941]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000157303	0.087	0.193	0.182	0	0.106	0.062	2	3	3	0	2	1	SUSD3	sushi domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28391]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000157315	0.158	0	0.071	0	0.063	0.363	3	0	1	0	1	5	TMED6	transmembrane p24 trafficking protein 6 [Source:HGNC Symbol;Acc:HGNC:28331]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	-	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization	--
ENSG00000157322	0.223	0.44	0.239	0.447	0.37	0.333	8.08	16.06	6.4	12	12.55	8.79	CLEC18A	C-type lectin domain family 18 member A [Source:HGNC Symbol;Acc:HGNC:30388]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding	-	--
ENSG00000157326	8.958	8.551	8.27	7.483	6.582	8.527	187.65	185.6	125	117.97	117.19	126.68	DHRS4	dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00830//Retinol metabolism	K11147;K11147;K11147	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol	"GO:0000253//3-keto sterol reductase activity;GO:0004090//carbonyl reductase (NADPH) activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0042802//identical protein binding;GO:0052650//NADP-retinol dehydrogenase activity"	GO:0006066//alcohol metabolic process;GO:0008202//steroid metabolic process;GO:0042180//cellular ketone metabolic process;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000157330	0.108	0.308	0.128	0	0.032	0.019	8	8	7	0	2	1	CFAP107	cilia and flagella associated protein 107 [Source:HGNC Symbol;Acc:HGNC:28567]	-	-	-	-	-	-	-	--
ENSG00000157335	0.248	0.38	0	0	0	0.094	3.3	5.7	0	0	0	3.15	CLEC18C	C-type lectin domain family 18 member C [Source:HGNC Symbol;Acc:HGNC:28538]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system	GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding	-	--
ENSG00000157343	0	0	0.056	0.056	0.146	0.17	0	0	1	1	3	3	ARMC12	armadillo repeat containing 12 [Source:HGNC Symbol;Acc:HGNC:21099]	-	-	-	-	GO:0005634//nucleus;GO:0005741//mitochondrial outer membrane;GO:0019898//extrinsic component of membrane	GO:0005515//protein binding	GO:0030307//positive regulation of cell growth;GO:0030317//flagellated sperm motility;GO:0120317//sperm mitochondrial sheath assembly	--
ENSG00000157349	16.012	16.653	16.027	13.406	16.461	15.706	606.38	656.92	470.32	407.94	467.32	398.28	DDX19B	DEAD-box helicase 19B [Source:HGNC Symbol;Acc:HGNC:2742]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K18655;K18655	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus	--
ENSG00000157350	7.032	7.037	7.368	6.221	6.168	6.032	1156	1162.02	894	757	856	721	ST3GAL2	"ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10863]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K03368;K03368;K03368;K03368;K03368	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0047288//monosialoganglioside sialyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0009247//glycolipid biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0010706//ganglioside biosynthetic process via lactosylceramide;GO:0010707//globoside biosynthetic process via lactosylceramide;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0019082//viral protein processing;GO:0030259//lipid glycosylation;GO:0097503//sialylation;GO:1990743//protein sialylation	--
ENSG00000157353	4.367	5.845	5.87	8.554	6.927	7.028	337	376	314	343	396	298	FCSK	fucose kinase [Source:HGNC Symbol;Acc:HGNC:29500]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K05305;K05305;K05305	GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0050201//fucokinase activity"	GO:0016310//phosphorylation;GO:0042352//GDP-L-fucose salvage;GO:0046835//carbohydrate phosphorylation;GO:1903350//response to dopamine	--
ENSG00000157368	5.528	6.174	5.651	4.427	5.678	4.507	204	229	154	121	177	121	IL34	interleukin 34 [Source:HGNC Symbol;Acc:HGNC:28529]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22633;K22633	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010759//positive regulation of macrophage chemotaxis;GO:0043406//positive regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0045651//positive regulation of macrophage differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0061514//interleukin-34-mediated signaling pathway;GO:0061518//microglial cell proliferation;GO:0120041//positive regulation of macrophage proliferation	--
ENSG00000157379	12.036	13.618	15.11	16.956	15.603	15.987	357	406	331	372	391	345	DHRS1	dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]	-	-	-	-	GO:0005783//endoplasmic reticulum	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	-	--
ENSG00000157388	0.647	0.754	1.183	0.974	0.966	1.004	83.28	93	63	90	104.02	93	CACNA1D	calcium voltage-gated channel subunit alpha1 D [Source:HGNC Symbol;Acc:HGNC:1391]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Signal transduction;Cardiovascular disease;Cell growth and death;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Circulatory system;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Endocrine system;Endocrine system;Cardiovascular disease;Circulatory system;Nervous system;Endocrine system;Cardiovascular disease;Endocrine system;Substance dependence;Endocrine system;Endocrine system;Endocrine and metabolic disease;Digestive system	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko04912//GnRH signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption"	K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851;K04851	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity;GO:0030506//ankyrin binding;GO:0046872//metal ion binding;GO:0051393//alpha-actinin binding;GO:0086007//voltage-gated calcium channel activity involved in cardiac muscle cell action potential;GO:0086059//voltage-gated calcium channel activity involved SA node cell action potential	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0045762//positive regulation of adenylate cyclase activity;GO:0051928//positive regulation of calcium ion transport;GO:0055085//transmembrane transport;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000157399	0.664	1.085	1.12	0.673	1.266	1.265	27	22	28	14	28	20	ARSL	arylsulfatase L [Source:HGNC Symbol;Acc:HGNC:719]	-	-	-	-	GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development	--
ENSG00000157404	1.048	0.791	1.009	1.268	1.338	1.972	113	79	80	100	122	153	KIT	"KIT proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342]"	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Immune system;Cancer: specific types;Endocrine system;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04640//Hematopoietic cell lineage;ko05224//Breast cancer;ko04916//Melanogenesis;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia	K05091;K05091;K05091;K05091;K05091;K05091;K05091;K05091;K05091;K05091;K05091	GO:0001650//fibrillar center;GO:0001669//acrosomal vesicle;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0002020//protease binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005020//stem cell factor receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019955//cytokine binding;GO:0042169//SH2 domain binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001541//ovarian follicle development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002318//myeloid progenitor cell differentiation;GO:0002320//lymphoid progenitor cell differentiation;GO:0002327//immature B cell differentiation;GO:0002551//mast cell chemotaxis;GO:0002573//myeloid leukocyte differentiation;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0006468//protein phosphorylation;GO:0006687//glycosphingolipid metabolic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008284//positive regulation of cell population proliferation;GO:0008354//germ cell migration;GO:0008360//regulation of cell shape;GO:0008542//visual learning;GO:0008584//male gonad development;GO:0009314//response to radiation;GO:0010628//positive regulation of gene expression;GO:0010863//positive regulation of phospholipase C activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0019827//stem cell population maintenance;GO:0030032//lamellipodium assembly;GO:0030097//hemopoiesis;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030318//melanocyte differentiation;GO:0030335//positive regulation of cell migration;GO:0031274//positive regulation of pseudopodium assembly;GO:0031401//positive regulation of protein modification process;GO:0031532//actin cytoskeleton reorganization;GO:0032765//positive regulation of mast cell cytokine production;GO:0033674//positive regulation of kinase activity;GO:0035019//somatic stem cell population maintenance;GO:0035162//embryonic hemopoiesis;GO:0035234//ectopic germ cell programmed cell death;GO:0035556//intracellular signal transduction;GO:0035701//hematopoietic stem cell migration;GO:0035855//megakaryocyte development;GO:0038093//Fc receptor signaling pathway;GO:0038109//Kit signaling pathway;GO:0038162//erythropoietin-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043069//negative regulation of programmed cell death;GO:0043303//mast cell degranulation;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043473//pigmentation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0043586//tongue development;GO:0045747//positive regulation of Notch signaling pathway;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046686//response to cadmium ion;GO:0046777//protein autophosphorylation;GO:0048066//developmental pigmentation;GO:0048103//somatic stem cell division;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0048565//digestive tract development;GO:0048584//positive regulation of response to stimulus;GO:0048863//stem cell differentiation;GO:0050673//epithelial cell proliferation;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060326//cell chemotaxis;GO:0060374//mast cell differentiation;GO:0070662//mast cell proliferation;GO:0097067//cellular response to thyroid hormone stimulus;GO:0097324//melanocyte migration;GO:0097326//melanocyte adhesion;GO:0120072//positive regulation of pyloric antrum smooth muscle contraction;GO:1904251//regulation of bile acid metabolic process;GO:1904343//positive regulation of colon smooth muscle contraction;GO:1904349//positive regulation of small intestine smooth muscle contraction;GO:1905065//positive regulation of vascular associated smooth muscle cell differentiation	--
ENSG00000157423	3.58	3.54	2.329	1.962	1.95	2.805	550	493	285	183	226	180	HYDIN	HYDIN axonemal central pair apparatus protein [Source:HGNC Symbol;Acc:HGNC:19368]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection;GO:1990716//axonemal central apparatus;GO:1990718//axonemal central pair projection	-	GO:0002064//epithelial cell development;GO:0003341//cilium movement;GO:0007420//brain development;GO:0021591//ventricular system development;GO:0060438//trachea development;GO:1904158//axonemal central apparatus assembly	--
ENSG00000157426	4.634	5.144	4.679	4.133	4.458	4.821	321	361	242	215	252	237	AASDH	aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016878//acid-thiol ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0019482//beta-alanine metabolic process;GO:0043041//amino acid activation for nonribosomal peptide biosynthetic process;GO:0071704//organic substance metabolic process	--
ENSG00000157429	4.077	3.58	3.947	3.321	3.145	2.973	166.89	176.95	101	93.6	115	92	ZNF19	zinc finger protein 19 [Source:HGNC Symbol;Acc:HGNC:12981]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000157445	0.274	0.158	0.444	0.036	0.24	0.203	6	10	10	2	8	11	CACNA2D3	calcium voltage-gated channel auxiliary subunit alpha2delta 3 [Source:HGNC Symbol;Acc:HGNC:15460]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04860;K04860;K04860;K04860;K04860;K04860;K04860	GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000157450	11.052	6.755	7.454	7.281	7.257	9.752	864	750	527	506	665	585	RNF111	ring finger protein 111 [Source:HGNC Symbol;Acc:HGNC:17384]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0032184//SUMO polymer binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007389//pattern specification process;GO:0016567//protein ubiquitination;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070911//global genome nucleotide-excision repair"	--
ENSG00000157456	1.276	1.805	2.032	0.962	1.112	1.007	43	56	48	22	29	23	CCNB2	cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes	Infectious disease: viral;Infectious disease: viral;Cell growth and death;Cell growth and death;Signal transduction;Cell growth and death;Endocrine system;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04218//Cellular senescence;ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko04115//p53 signaling pathway	K21770;K21770;K21770;K21770;K21770;K21770;K21770;K21770	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0045296//cadherin binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001701//in utero embryonic development;GO:0007049//cell cycle;GO:0007057//spindle assembly involved in female meiosis I;GO:0008315//G2/MI transition of meiotic cell cycle;GO:0040008//regulation of growth;GO:0043029//T cell homeostasis;GO:0044772//mitotic cell cycle phase transition;GO:0048538//thymus development;GO:0051301//cell division	--
ENSG00000157470	1.02	1.072	1.072	0.661	0.661	0.402	54	54	31	28	19	21	FAM81A	family with sequence similarity 81 member A [Source:HGNC Symbol;Acc:HGNC:28379]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000157483	31.411	38.919	34.199	27.026	21.396	27.692	4043	4224	2566	2034	2495	2210	MYO1E	myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0005912//adherens junction;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0032437//cuticular plate;GO:0032991//protein-containing complex;GO:0045334//clathrin-coated endocytic vesicle;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016887//ATP hydrolysis activity;GO:0035091//phosphatidylinositol binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding	GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0003094//glomerular filtration;GO:0006807//nitrogen compound metabolic process;GO:0006897//endocytosis;GO:0007015//actin filament organization;GO:0030050//vesicle transport along actin filament;GO:0030097//hemopoiesis;GO:0032836//glomerular basement membrane development;GO:0035166//post-embryonic hemopoiesis;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0072015//glomerular visceral epithelial cell development	--
ENSG00000157500	10.305	8.411	7.772	6.606	9.767	8.512	1250	974	699	615	873	701	APPL1	"adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 [Source:HGNC Symbol;Acc:HGNC:24035]"	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Aging;Cancer: specific types	ko05200//Pathways in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer	K08733;K08733;K08733	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032009//early phagosome;GO:0042995//cell projection;GO:0044354//macropinosome;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0097708//intracellular vesicle	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043422//protein kinase B binding;GO:0044877//protein-containing complex binding;GO:0048487//beta-tubulin binding	GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0010762//regulation of fibroblast migration;GO:0023052//signaling;GO:0033211//adiponectin-activated signaling pathway;GO:0034143//regulation of toll-like receptor 4 signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0045088//regulation of innate immune response;GO:0046324//regulation of glucose import;GO:0046326//positive regulation of glucose import;GO:0048023//positive regulation of melanin biosynthetic process;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1903076//regulation of protein localization to plasma membrane;GO:1905303//positive regulation of macropinocytosis;GO:1905450//negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000157502	1.072	1.276	0.688	0.811	0.752	0.79	91	111	44	52	54	49	PWWP3B	PWWP domain containing 3B [Source:HGNC Symbol;Acc:HGNC:26583]	-	-	-	-	GO:0070062//extracellular exosome	-	-	--
ENSG00000157510	0.491	0.449	0.701	0.538	0.581	0.438	41	39	32	31	42	31	AFAP1L1	actin filament associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:26714]	-	-	-	-	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0042995//cell projection	GO:0005515//protein binding;GO:0017124//SH3 domain binding	-	--
ENSG00000157514	23.478	22.908	22.22	19.666	21.786	25.446	955	897	642	581	701	721	TSC22D3	TSC22 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:3051]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006970//response to osmotic stress;GO:0070236//negative regulation of activation-induced cell death of T cells	TSC22
ENSG00000157538	25.583	24.871	25.561	25.382	23.287	29.609	1352	1292	973	977	1067	1062	VPS26C	VPS26 endosomal protein sorting factor C [Source:HGNC Symbol;Acc:HGNC:3044]	-	-	-	-	GO:0005634//nucleus;GO:0005768//endosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0032456//endocytic recycling	--
ENSG00000157540	12.359	11.795	13.659	10.085	10.851	12.225	1236	1135	719	627	885	904	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005883//neurofilament;GO:0005884//actin filament;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0015631//tubulin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0007623//circadian rhythm;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031115//negative regulation of microtubule polymerization;GO:0033120//positive regulation of RNA splicing;GO:0034205//amyloid-beta formation;GO:0036289//peptidyl-serine autophosphorylation;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0090312//positive regulation of protein deacetylation"	--
ENSG00000157542	0	0	0	0	0	0	0	0	0	0	0	0	KCNJ6	potassium inwardly rectifying channel subfamily J member 6 [Source:HGNC Symbol;Acc:HGNC:6267]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Endocrine system;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Endocrine system	ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04929//GnRH secretion	K05000;K05000;K05000;K05000;K05000;K05000;K05000;K05000;K05000;K05000	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000157551	0	0.019	0	0	0	0.008	0	2	0	0	0	1	KCNJ15	potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K05008	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000157554	0.206	0.51	0.056	0.059	0.188	0.083	21	38	4	3	10	6	ERG	ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05215//Prostate cancer	K09435;K09435	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000157557	19.18	20.086	15.508	15.225	15.14	14.823	1259	1281	746	717	819	716	ETS2	"ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489]"	Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral	ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection	K21932;K21932	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001712//ectodermal cell fate commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007498//mesoderm development;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090009//primitive streak formation"	ETS
ENSG00000157570	1.978	3.138	1.82	3.186	2.174	1.73	164	223	123	146	158	119	TSPAN18	tetraspanin 18 [Source:HGNC Symbol;Acc:HGNC:20660]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000157578	0.563	0.971	0.256	0.255	0.179	0.208	27	33	10	10	8	8	LCA5L	lebercilin LCA5 like [Source:HGNC Symbol;Acc:HGNC:1255]	-	-	-	-	GO:0005930//axoneme	GO:0005515//protein binding	GO:0042073//intraciliary transport	--
ENSG00000157593	35.825	35.548	41.574	43.645	40.961	37.592	1500	1498	1287	1353	1449	1147	SLC35B2	solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity;GO:0046964//3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046963//3'-phosphoadenosine 5'-phosphosulfate transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0055085//transmembrane transport;GO:1902559//3'-phospho-5'-adenylyl sulfate transmembrane transport	--
ENSG00000157600	99.085	100.466	122.409	132.042	124.881	131.531	11143	11351	10128	10940	11891	10773	TMEM164	transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000157601	2.308	3.817	3.581	3.331	3.717	2.99	128	225	153	139	186	120	MX1	MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral	ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05164//Influenza A;ko05160//Hepatitis C;ko05162//Measles	K14754;K14754;K14754;K14754;K14754	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005874//microtubule;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006952//defense response;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0034340//response to type I interferon;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0070106//interleukin-27-mediated signaling pathway;GO:0140374//antiviral innate immune response	--
ENSG00000157613	2.453	2.674	1.319	2.995	3.532	2.695	136	149	54	123	146	101	CREB3L1	cAMP responsive element binding protein 3 like 1 [Source:HGNC Symbol;Acc:HGNC:18856]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:0046332//SMAD binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006986//response to unfolded protein;GO:0010629//negative regulation of gene expression;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032967//positive regulation of collagen biosynthetic process;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070278//extracellular matrix constituent secretion;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903671//negative regulation of sprouting angiogenesis;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	TF_bZIP
ENSG00000157617	3.586	3.73	3.888	3.848	4.303	4.186	465	463	367	368	458	375	C2CD2	C2 calcium dependent domain containing 2 [Source:HGNC Symbol;Acc:HGNC:1266]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000157625	6.961	6.069	5.841	5.323	5.303	6.553	903	780	569	525	577	586	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3 [Source:HGNC Symbol;Acc:HGNC:30681]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Signal transduction;Endocrine and metabolic disease;Signal transduction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04936//Alcoholic liver disease;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway	K12793;K12793;K12793;K12793;K12793;K12793;K12793;K12793	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0010507//negative regulation of autophagy;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000157637	39.153	40.651	36.86	39.273	39.491	38.498	3012	3212	2230	2247	2688	2228	SLC38A10	solute carrier family 38 member 10 [Source:HGNC Symbol;Acc:HGNC:28237]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015171//amino acid transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0060348//bone development	--
ENSG00000157653	0.435	0.385	0.426	0.555	0.086	0.356	18	16	13	17	3	11	C9orf43	chromosome 9 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:23570]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000157654	16.333	15.409	13.445	13.559	15.536	12.075	1956	1884	1184	1187	1517	1041	PALM2AKAP2	PALM2 and AKAP2 fusion [Source:HGNC Symbol;Acc:HGNC:33529]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0008360//regulation of cell shape	--
ENSG00000157657	11.854	10.629	10.796	11.113	11.649	11.542	2009	1749	1368	1486	1697	1568	ZNF618	zinc finger protein 618 [Source:HGNC Symbol;Acc:HGNC:29416]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin	GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0035563//positive regulation of chromatin binding"	zf-C2H2
ENSG00000157680	0.623	0.442	0.463	0.468	0.309	0.759	170	113	95	93	73	149	DGKI	diacylglycerol kinase iota [Source:HGNC Symbol;Acc:HGNC:2855]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism	K00901;K00901;K00901;K00901;K00901;K00901	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	"GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007269//neurotransmitter secretion;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043087//regulation of GTPase activity;GO:0044255//cellular lipid metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046579//positive regulation of Ras protein signal transduction;GO:0046834//lipid phosphorylation;GO:0046959//habituation;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:1900452//regulation of long-term synaptic depression;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000157693	13.846	14.204	13.721	13.618	13.316	17.213	1291	1330	947	940	1048	1169	TMEM268	transmembrane protein 268 [Source:HGNC Symbol;Acc:HGNC:24513]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000157703	0.885	0.935	0.957	0.664	0.821	0.422	29	31	27	16	20	9	SVOPL	SVOP like [Source:HGNC Symbol;Acc:HGNC:27034]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000157734	0.258	0.256	0.333	0.367	0.28	0.31	19.29	19.25	18.36	20.3	17.68	16.84	SNX22	sorting nexin 22 [Source:HGNC Symbol;Acc:HGNC:16315]	-	-	-	-	GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0015031//protein transport	--
ENSG00000157741	2.175	1.352	1.493	1.212	1.574	1.547	649	414	336	244	397	313	UBN2	ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm	-	GO:0006336//DNA replication-independent nucleosome assembly	--
ENSG00000157764	3.889	3.263	4.192	3.062	3.281	4.156	535.46	440.8	358.68	287.5	379.79	413.95	BRAF	"B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: overview;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Immune system;Substance dependence;Immune system;Cancer: specific types;Infectious disease: viral;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Circulatory system;Nervous system;Nervous system;Endocrine system;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Nervous system;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04722//Neurotrophin signaling pathway;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365;K04365	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0002318//myeloid progenitor cell differentiation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008152//metabolic process;GO:0008542//visual learning;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010764//negative regulation of fibroblast migration;GO:0010828//positive regulation of glucose transmembrane transport;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030878//thyroid gland development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035019//somatic stem cell population maintenance;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0043368//positive T cell selection;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0043524//negative regulation of neuron apoptotic process;GO:0045580//regulation of T cell differentiation;GO:0046632//alpha-beta T cell differentiation;GO:0048538//thymus development;GO:0048679//regulation of axon regeneration;GO:0048680//positive regulation of axon regeneration;GO:0050772//positive regulation of axonogenesis;GO:0050852//T cell receptor signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0060291//long-term synaptic potentiation;GO:0060323//head morphogenesis;GO:0060324//face development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070413//trehalose metabolism in response to stress;GO:0071277//cellular response to calcium ion;GO:0071466//cellular response to xenobiotic stimulus;GO:0090150//establishment of protein localization to membrane;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902531//regulation of intracellular signal transduction;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:2000352//negative regulation of endothelial cell apoptotic process"	--
ENSG00000157765	0.739	0.548	0.278	1.307	0.582	1.106	33	29	16	42	42	32	SLC34A2	solute carrier family 34 member 2 [Source:HGNC Symbol;Acc:HGNC:11020]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	"ko04928//Parathyroid hormone synthesis, secretion and action;ko04978//Mineral absorption"	K14683;K14683	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031982//vesicle	GO:0005436//sodium:phosphate symporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0031402//sodium ion binding;GO:0042301//phosphate ion binding	GO:0001701//in utero embryonic development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0030643//cellular phosphate ion homeostasis;GO:0035725//sodium ion transmembrane transport;GO:0043627//response to estrogen;GO:0044267//cellular protein metabolic process;GO:0044341//sodium-dependent phosphate transport;GO:0055085//transmembrane transport	--
ENSG00000157766	0.006	0	0.017	0	0	0.016	1	0	2	0	0	1	ACAN	aggrecan [Source:HGNC Symbol;Acc:HGNC:319]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005796//Golgi lumen;GO:0012505//endomembrane system;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0098966//perisynaptic extracellular matrix;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001502//cartilage condensation;GO:0002063//chondrocyte development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0030166//proteoglycan biosynthetic process;GO:0030199//collagen fibril organization	--
ENSG00000157778	11.013	9.552	10.466	9.01	9.457	12.349	217	175	147	137	139	167	PSMG3	proteasome assembly chaperone 3 [Source:HGNC Symbol;Acc:HGNC:22420]	-	-	-	-	GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0060090//molecular adaptor activity	GO:0043248//proteasome assembly;GO:0051131//chaperone-mediated protein complex assembly	--
ENSG00000157782	0	0.026	0	0	0	0	0	1	0	0	0	0	CABP1	calcium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1384]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0004857//enzyme inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0007601//visual perception;GO:0042308//negative regulation of protein import into nucleus;GO:0043086//negative regulation of catalytic activity;GO:0050896//response to stimulus	--
ENSG00000157796	7.503	9.12	6.253	7.128	6.011	8.001	684	664	421	338	453	420	WDR19	WD repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:18340]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030991//intraciliary transport particle A;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097730//non-motile cilium	GO:0005515//protein binding	GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0007224//smoothened signaling pathway;GO:0008406//gonad development;GO:0030030//cell projection organization;GO:0030326//embryonic limb morphogenesis;GO:0031076//embryonic camera-type eye development;GO:0035721//intraciliary retrograde transport;GO:0042471//ear morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050877//nervous system process;GO:0055123//digestive system development;GO:0060271//cilium assembly;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0061055//myotome development;GO:0065003//protein-containing complex assembly;GO:1903441//protein localization to ciliary membrane	--
ENSG00000157800	5.722	6.554	4.784	6.12	5.656	6.252	284	336	178	199	267	224	SLC37A3	solute carrier family 37 member 3 [Source:HGNC Symbol;Acc:HGNC:20651]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0022857//transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport	--
ENSG00000157823	36.611	36.109	37.554	28.888	35.244	39.737	1672.86	1740.92	1345.93	1436.92	1611.54	1500.68	AP3S2	adaptor related protein complex 3 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:571]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12399	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030123//AP-3 adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1904115//axon cytoplasm	-	"GO:0006886//intracellular protein transport;GO:0006896//Golgi to vacuole transport;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016183//synaptic vesicle coating;GO:0016192//vesicle-mediated transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0036465//synaptic vesicle recycling;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly"	--
ENSG00000157827	29.07	22.778	23.799	19.477	21.82	21.948	3341	2515	1970	1596	2090	1794	FMNL2	formin like 2 [Source:HGNC Symbol;Acc:HGNC:18267]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003779//actin binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0016043//cellular component organization;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization	--
ENSG00000157833	2.279	2.608	2.116	2.244	2.799	2.938	198	228	135	144	205	185	GAREM2	GRB2 associated regulator of MAPK1 subtype 2 [Source:HGNC Symbol;Acc:HGNC:27172]	-	-	-	-	-	-	-	--
ENSG00000157837	20.243	22.284	23.274	19.307	22.091	26.853	1264	1318	995	918	1065	1017	SPPL3	signal peptide peptidase like 3 [Source:HGNC Symbol;Acc:HGNC:30424]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0042803//protein homodimerization activity"	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032092//positive regulation of protein binding;GO:0033619//membrane protein proteolysis;GO:0035307//positive regulation of protein dephosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000157851	1.161	1.253	1.021	2.883	2.378	2.677	95	135	81	153	196	166	DPYSL5	dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07529	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body	"GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030182//neuron differentiation	--
ENSG00000157856	1.105	1.659	0.604	0.497	0.184	0.272	57	86	23	19	8	10	DRC1	dynein regulatory complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24245]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection	-	GO:0003352//regulation of cilium movement;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0060285//cilium-dependent cell motility;GO:0070286//axonemal dynein complex assembly	--
ENSG00000157869	6.166	5.779	8.455	7.081	5.62	8.487	219	204	218	183	168	216	RAB28	"RAB28, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9768]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0035253//ciliary rootlet;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0006886//intracellular protein transport;GO:1901998//toxin transport	--
ENSG00000157870	16.738	16.203	17.499	21.2	18.969	23.442	915.52	859.1	705.52	862.89	889	876.58	PRXL2B	peroxiredoxin like 2B [Source:HGNC Symbol;Acc:HGNC:28390]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K15717;K15717	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047017//prostaglandin-F synthase activity"	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000157873	61.808	57.678	65.337	74.085	70.076	76.917	1807	1713	1465	1615	1737	1673	TNFRSF14	TNF receptor superfamily member 14 [Source:HGNC Symbol;Acc:HGNC:11912]	Human Diseases;Environmental Information Processing;Environmental Information Processing	Infectious disease: viral;Signaling molecules and interaction;Signaling molecules and interaction	ko05168//Herpes simplex virus 1 infection;ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05152;K05152;K05152	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0031625//ubiquitin protein ligase binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045087//innate immune response;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0046718//viral entry into host cell;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:1905675//negative regulation of adaptive immune memory response;GO:2000406//positive regulation of T cell migration	--
ENSG00000157881	8.922	8.677	9.171	9.26	9.486	10.923	461	462	342	357	418	388	PANK4	pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004594//pantothenate kinase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000157884	0	0	0	0	0	0	0	0	0	0	0	0	CIB4	calcium and integrin binding family member 4 [Source:HGNC Symbol;Acc:HGNC:33703]	-	-	-	-	-	GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000157890	0.235	0.688	0.209	0.046	0.028	0.046	19	29	8	4	3	4	MEGF11	multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding	GO:0010842//retina layer formation;GO:0034109//homotypic cell-cell adhesion	--
ENSG00000157895	7.601	7.611	9.905	9.08	8.136	6.952	366	345	306	315	312	221	C12orf43	chromosome 12 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:25719]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope	GO:0005515//protein binding	GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0060061//Spemann organizer formation	--
ENSG00000157911	10.15	11.234	11.967	11.514	12.318	11.408	597.47	663.97	510.72	501.73	611.94	482.1	PEX10	peroxisomal biogenesis factor 10 [Source:HGNC Symbol;Acc:HGNC:8851]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13346	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix	--
ENSG00000157916	54.718	60.857	55.676	60.544	54.435	62.431	2248.53	2403.03	1763.28	1898.27	1995.06	1938.9	RER1	retention in endoplasmic reticulum sorting receptor 1 [Source:HGNC Symbol;Acc:HGNC:30309]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0033130//acetylcholine receptor binding	"GO:0006621//protein retention in ER lumen;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007528//neuromuscular junction development;GO:0051179//localization;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:1903078//positive regulation of protein localization to plasma membrane"	--
ENSG00000157927	0.085	0.075	0.057	0.034	0.06	0.092	1	9	5	3	6	8	RADIL	Rap associating with DIL domain [Source:HGNC Symbol;Acc:HGNC:22226]	-	-	-	-	GO:0005874//microtubule;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0051020//GTPase binding	GO:0001755//neural crest cell migration;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0034446//substrate adhesion-dependent cell spreading	--
ENSG00000157933	18.522	17.544	18.565	18.2	20.104	19.062	2337	2225	1730	1701	2143	1750	SKI	SKI proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10896]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016604//nuclear body;GO:0016605//PML body;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0046811//histone deacetylase inhibitor activity;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001843//neural tube closure;GO:0002089//lens morphogenesis in camera-type eye;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0009948//anterior/posterior axis specification;GO:0010626//negative regulation of Schwann cell proliferation;GO:0014902//myotube differentiation;GO:0021772//olfactory bulb development;GO:0022011//myelination in peripheral nervous system;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030326//embryonic limb morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0031064//negative regulation of histone deacetylation;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0043010//camera-type eye development;GO:0043388//positive regulation of DNA binding;GO:0043585//nose morphogenesis;GO:0045668//negative regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048147//negative regulation of fibroblast proliferation;GO:0048593//camera-type eye morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0048870//cell motility;GO:0060021//roof of mouth development;GO:0060041//retina development in camera-type eye;GO:0060325//face morphogenesis;GO:0060349//bone morphogenesis;GO:0060395//SMAD protein signal transduction"	--
ENSG00000157954	37.462	37.366	36.438	38.058	38.695	37.668	1880	1926	1400	1417	1651	1439	WIPI2	"WD repeat domain, phosphoinositide interacting 2 [Source:HGNC Symbol;Acc:HGNC:32225]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04136//Autophagy - other	K17908;K17908;K17908;K17908;K17908;K17908;K17908;K17908	GO:0000407//phagophore assembly site;GO:0005654//nucleoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0032991//protein-containing complex;GO:0034045//phagophore assembly site membrane	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0034497//protein localization to phagophore assembly site;GO:0044804//autophagy of nucleus;GO:0061739//protein lipidation involved in autophagosome assembly;GO:0098792//xenophagy	--
ENSG00000157978	10.01	12.213	10.573	12.441	13.316	12.574	605	742	472	557	680	553	LDLRAP1	low density lipoprotein receptor adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:18640]	Cellular Processes;Organismal Systems	Transport and catabolism;Digestive system	ko04144//Endocytosis;ko04979//Cholesterol metabolism	K12474;K12474	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0009925//basal plasma membrane;GO:0030424//axon;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0055037//recycling endosome	"GO:0001540//amyloid-beta binding;GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030276//clathrin binding;GO:0035591//signaling adaptor activity;GO:0035612//AP-2 adaptor complex binding;GO:0035615//clathrin adaptor activity;GO:0035650//AP-1 adaptor complex binding;GO:0050750//low-density lipoprotein particle receptor binding"	GO:0006629//lipid metabolic process;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0031623//receptor internalization;GO:0034383//low-density lipoprotein particle clearance;GO:0042632//cholesterol homeostasis;GO:0042982//amyloid precursor protein metabolic process;GO:0043393//regulation of protein binding;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0071345//cellular response to cytokine stimulus;GO:0090118//receptor-mediated endocytosis involved in cholesterol transport;GO:0090205//positive regulation of cholesterol metabolic process;GO:1903076//regulation of protein localization to plasma membrane;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905581//positive regulation of low-density lipoprotein particle clearance;GO:1905602//positive regulation of receptor-mediated endocytosis involved in cholesterol transport	--
ENSG00000157985	5.167	4.11	5.375	6.673	7.244	7.018	732	650	611	756	974	774	AGAP1	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16922]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0050790//regulation of catalytic activity	--
ENSG00000157992	1.2	2.271	1.227	1.259	0.496	1.272	18	33	13	17	8	14	KRTCAP3	keratinocyte associated protein 3 [Source:HGNC Symbol;Acc:HGNC:28943]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000157999	0.305	0.135	0.138	0.137	0.04	0.419	9	4	3	3	1	9	ANKRD61	ankyrin repeat domain 61 [Source:HGNC Symbol;Acc:HGNC:22467]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000158006	6.664	6.144	7.33	7.678	8.601	7.946	408	394	344	348	435	336	PAFAH2	platelet activating factor acetylhydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8579]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K01062;K01062	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0005543//phospholipid binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0047179//platelet-activating factor acetyltransferase activity	GO:0006629//lipid metabolic process;GO:0007596//blood coagulation;GO:0016042//lipid catabolic process	--
ENSG00000158008	0.312	0.489	0.244	0.291	0.341	0.198	26	41	15	18	24	12	EXTL1	exostosin like glycosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3515]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02368;K02368	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	GO:0001501//skeletal system development;GO:0006486//protein glycosylation	--
ENSG00000158014	0.031	0.133	0.063	0.06	0.018	0.107	2	9	3	3	1	5	SLC30A2	solute carrier family 30 member 2 [Source:HGNC Symbol;Acc:HGNC:11013]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0010043//response to zinc ion;GO:0055085//transmembrane transport;GO:0061088//regulation of sequestering of zinc ion;GO:0061090//positive regulation of sequestering of zinc ion;GO:0071577//zinc ion transmembrane transport	--
ENSG00000158019	20.328	24.501	23.962	25.053	25.366	23.141	715.52	869	621	657	753	592	BABAM2	BRISC and BRCA1 A complex member 2 [Source:HGNC Symbol;Acc:HGNC:1106]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K12173	GO:0000152//nuclear ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070531//BRCA1-A complex;GO:0070552//BRISC complex	GO:0000268//peroxisome targeting sequence binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007165//signal transduction;GO:0010212//response to ionizing radiation;GO:0035518//histone H2A monoubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0044818//mitotic G2/M transition checkpoint;GO:0045739//positive regulation of DNA repair;GO:0051301//cell division;GO:0051865//protein autoubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0070537//histone H2A K63-linked deubiquitination;GO:0071479//cellular response to ionizing radiation;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000158022	7.327	7.479	7.265	6.251	6.222	6.214	269	276	197	170	193	166	TRIM63	tripartite motif containing 63 [Source:HGNC Symbol;Acc:HGNC:16007]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0030018//Z disc;GO:0031430//M band;GO:0043292//contractile fiber	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031432//titin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0014732//skeletal muscle atrophy;GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination;GO:0051384//response to glucocorticoid;GO:0070555//response to interleukin-1	--
ENSG00000158023	1.423	1.321	0.973	1.052	0.561	0.905	102	97	51	56	35	48	CFAP251	cilia and flagella associated protein 251 [Source:HGNC Symbol;Acc:HGNC:28506]	-	-	-	-	GO:0001536//radial spoke stalk;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0030317//flagellated sperm motility	--
ENSG00000158042	12.396	17.559	12.574	11.069	14.897	13.937	440	525	444	392	405	428	MRPL17	mitochondrial ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:14053]	Genetic Information Processing	Translation	ko03010//Ribosome	K02879	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000158050	1.917	2.363	1.666	2.009	1.998	2.674	67	83	43	52	59	68	DUSP2	dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031965//nuclear membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0001706//endoderm formation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade	--
ENSG00000158055	0	0	0.096	0.116	0	0	0	0	3	3	0	0	GRHL3	grainyhead like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:25839]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding"	"GO:0001736//establishment of planar polarity;GO:0001843//neural tube closure;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007398//ectoderm development;GO:0007417//central nervous system development;GO:0008544//epidermis development;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0032956//regulation of actin cytoskeleton organization;GO:0042060//wound healing;GO:0043547//positive regulation of GTPase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061029//eyelid development in camera-type eye;GO:0061436//establishment of skin barrier;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure"	CP2
ENSG00000158062	10.855	12.278	13.836	10.725	10.551	10.586	331	374	298.01	249	268.01	250	UBXN11	UBX domain protein 11 [Source:HGNC Symbol;Acc:HGNC:30600]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000158077	0.013	0.05	0.137	0.017	0.06	0	1	4	8	1	4	0	NLRP14	NLR family pyrin domain containing 14 [Source:HGNC Symbol;Acc:HGNC:22939]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000158079	1.473	1.287	1.098	0.888	1.203	1.115	138	120	76	60	95	76	PTPDC1	protein tyrosine phosphatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30184]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007224//smoothened signaling pathway;GO:0016311//dephosphorylation;GO:0030030//cell projection organization;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060271//cilium assembly	--
ENSG00000158089	4.334	5.482	4.467	5.501	4.429	4.008	218	275	164	201	184	148	GALNT14	polypeptide N-acetylgalactosaminyltransferase 14 [Source:HGNC Symbol;Acc:HGNC:22946]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing	--
ENSG00000158092	15.463	11.413	12	11.07	12.118	14.583	673	514	401	361	432	463	NCK1	NCK adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:7664]	Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing	Infectious disease: bacterial;Development and regeneration;Immune system;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway	K07365;K07365;K07365;K07365	GO:0000164//protein phosphatase type 1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0012506//vesicle membrane	GO:0003779//actin binding;GO:0004860//protein kinase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0019904//protein domain specific binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030674//protein-macromolecule adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity;GO:0045296//cadherin binding;GO:0046875//ephrin receptor binding;GO:0071074//eukaryotic initiation factor eIF2 binding	"GO:0006417//regulation of translation;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0007172//signal complex assembly;GO:0010976//positive regulation of neuron projection development;GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0030334//regulation of cell migration;GO:0030838//positive regulation of actin filament polymerization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0036493//positive regulation of translation in response to endoplasmic reticulum stress;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0043086//negative regulation of catalytic activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0051016//barbed-end actin filament capping;GO:0051017//actin filament bundle assembly;GO:0051707//response to other organism;GO:0060548//negative regulation of cell death;GO:0070262//peptidyl-serine dephosphorylation;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903676//positive regulation of cap-dependent translational initiation;GO:1903679//positive regulation of cap-independent translational initiation;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	--
ENSG00000158104	2.736	3.055	2.664	1.422	1.273	1.793	82	91	59	31	34	39	HPD	4-hydroxyphenylpyruvate dioxygenase [Source:HGNC Symbol;Acc:HGNC:5147]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism;ko00360//Phenylalanine metabolism;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K00457;K00457;K00457;K00457	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006559//L-phenylalanine catabolic process;GO:0006572//tyrosine catabolic process;GO:0009072//aromatic amino acid family metabolic process	--
ENSG00000158106	3.836	3.583	3.869	3.294	4.062	4.447	294	276	219	187	263	248	RHPN1	rhophilin Rho GTPase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19973]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0051497//negative regulation of stress fiber assembly	--
ENSG00000158109	11.747	12.386	11.673	12.659	11.86	13.191	585	620	429	467	499	478	TPRG1L	tumor protein p63 regulated 1 like [Source:HGNC Symbol;Acc:HGNC:27007]	-	-	-	-	GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0070062//extracellular exosome	GO:0003674//molecular_function	"GO:0008150//biological_process;GO:0051966//regulation of synaptic transmission, glutamatergic"	--
ENSG00000158113	1.241	1.915	1.114	1.22	1.586	1.114	42	51	30	30	39	34	LRRC43	leucine rich repeat containing 43 [Source:HGNC Symbol;Acc:HGNC:28562]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000158122	1.784	1.522	1.59	1.751	1.354	1.91	106	92	70	78	68	83	PRXL2C	peroxiredoxin like 2C [Source:HGNC Symbol;Acc:HGNC:16881]	-	-	-	-	-	GO:0016209//antioxidant activity	GO:0045821//positive regulation of glycolytic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0098869//cellular oxidant detoxification	--
ENSG00000158125	0.422	0.269	0.331	0.194	0.429	0.325	50	32	29	17	43	28	XDH	xanthine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:12805]	Metabolism;Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Transport and catabolism;Xenobiotics biodegradation and metabolism;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04146//Peroxisome;ko00983//Drug metabolism - other enzymes;ko00232//Caffeine metabolism	K00106;K00106;K00106;K00106;K00106	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum	"GO:0004854//xanthine dehydrogenase activity;GO:0004855//xanthine oxidase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042803//protein homodimerization activity;GO:0043546//molybdopterin cofactor binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0070674//hypoxanthine dehydrogenase activity;GO:0070675//hypoxanthine oxidase activity;GO:0071949//FAD binding"	GO:0000255//allantoin metabolic process;GO:0001933//negative regulation of protein phosphorylation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006147//guanine catabolic process;GO:0006148//inosine catabolic process;GO:0006149//deoxyinosine catabolic process;GO:0006154//adenosine catabolic process;GO:0006157//deoxyadenosine catabolic process;GO:0006161//deoxyguanosine catabolic process;GO:0006196//AMP catabolic process;GO:0006204//IMP catabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007595//lactation;GO:0009114//hypoxanthine catabolic process;GO:0009115//xanthine catabolic process;GO:0010629//negative regulation of gene expression;GO:0016226//iron-sulfur cluster assembly;GO:0030856//regulation of epithelial cell differentiation;GO:0045602//negative regulation of endothelial cell differentiation;GO:0046038//GMP catabolic process;GO:0046055//dGMP catabolic process;GO:0046059//dAMP catabolic process;GO:0051898//negative regulation of protein kinase B signaling;GO:1900745//positive regulation of p38MAPK cascade;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2001213//negative regulation of vasculogenesis	--
ENSG00000158156	9.242	9.54	10.008	10.45	10.232	9.755	385	423	311	318	366	313	XKR8	XK related 8 [Source:HGNC Symbol;Acc:HGNC:25508]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0017128//phospholipid scramblase activity	GO:0002513//tolerance induction to self antigen;GO:0006915//apoptotic process;GO:0043652//engulfment of apoptotic cell;GO:0045663//positive regulation of myoblast differentiation;GO:0051649//establishment of localization in cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:0097350//neutrophil clearance;GO:1902742//apoptotic process involved in development	--
ENSG00000158158	3.992	3.71	4.913	3.361	3.937	4.669	396	370	360	247	330	337	CNNM4	cyclin and CBS domain divalent metal cation transport mediator 4 [Source:HGNC Symbol;Acc:HGNC:105]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0007601//visual perception;GO:0010960//magnesium ion homeostasis;GO:0015693//magnesium ion transport;GO:0031214//biomineral tissue development;GO:0035725//sodium ion transmembrane transport;GO:0050896//response to stimulus;GO:0055065//metal ion homeostasis;GO:0055085//transmembrane transport;GO:0070166//enamel mineralization;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000158161	12.496	10.239	9.267	7.261	8.69	9.116	1234	1057	836	664	906	819	EYA3	EYA transcriptional coactivator and phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:3521]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007275//multicellular organism development;GO:0007601//visual perception;GO:0009653//anatomical structure morphogenesis;GO:0010212//response to ionizing radiation;GO:0016576//histone dephosphorylation;GO:0030154//cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045739//positive regulation of DNA repair;GO:0048856//anatomical structure development;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000158163	2.175	2.228	2.467	1.935	2.559	2.657	92	97	81	63	83	89	DZIP1L	DAZ interacting zinc finger protein 1 like [Source:HGNC Symbol;Acc:HGNC:26551]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007224//smoothened signaling pathway;GO:0021532//neural tube patterning;GO:0032880//regulation of protein localization;GO:0033365//protein localization to organelle;GO:0033504//floor plate development;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1905349//ciliary transition zone assembly	--
ENSG00000158164	0.684	0.681	0.206	0.821	0.27	0.105	9	9	2	8	3	1	TMSB15A	thymosin beta 15A [Source:HGNC Symbol;Acc:HGNC:30744]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0003785//actin monomer binding	GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers	--
ENSG00000158169	2.516	2.178	2.783	3.304	2.712	3.968	233	203	163	186	213	219	FANCC	FA complementation group C [Source:HGNC Symbol;Acc:HGNC:3584]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10890	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043240//Fanconi anaemia nuclear complex	GO:0005515//protein binding	GO:0002262//myeloid cell homeostasis;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007276//gamete generation;GO:0007281//germ cell development;GO:0019430//removal of superoxide radicals;GO:0034599//cellular response to oxidative stress;GO:0036297//interstrand cross-link repair;GO:0048854//brain morphogenesis;GO:0065003//protein-containing complex assembly;GO:0097150//neuronal stem cell population maintenance	--
ENSG00000158186	24.922	31.724	28.264	31.324	27.626	27.184	2122	2156	1731	1601	1820	1632	MRAS	muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cancer: overview;Cell growth and death;Transport and catabolism;Signal transduction;Immune system;Transport and catabolism	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04137//Mitophagy - animal	K07831;K07831;K07831;K07831;K07831;K07831;K07831;K07831;K07831;K07831;K07831	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0030742//GTP-dependent protein binding	GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000158195	26.213	27.372	23.959	28.052	27.115	22.998	2590	2822	1974	2079	2308	1877	WASF2	WASP family member 2 [Source:HGNC Symbol;Acc:HGNC:12733]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Infectious disease: bacterial;Immune system;Cancer: overview;Infectious disease: bacterial;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko05100//Bacterial invasion of epithelial cells;ko04520//Adherens junction	K05748;K05748;K05748;K05748;K05748;K05748;K05748;K05748	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0045296//cadherin binding;GO:0051018//protein kinase A binding;GO:0071933//Arp2/3 complex binding	GO:0001525//angiogenesis;GO:0001667//ameboidal-type cell migration;GO:0006897//endocytosis;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0010592//positive regulation of lamellipodium assembly;GO:0016601//Rac protein signal transduction;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0030048//actin filament-based movement;GO:0035855//megakaryocyte development;GO:0051497//negative regulation of stress fiber assembly;GO:0072673//lamellipodium morphogenesis;GO:0098974//postsynaptic actin cytoskeleton organization;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000158201	7.849	6.446	6.956	6.302	8.337	10.762	313	273	217	197	202	252	ABHD3	"abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718]"	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004623//phospholipase A2 activity;GO:0008126//acetylesterase activity;GO:0008970//phospholipase A1 activity;GO:0016787//hydrolase activity;GO:0034338//short-chain carboxylesterase activity;GO:0047372//acylglycerol lipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0051792//medium-chain fatty acid biosynthetic process;GO:0051793//medium-chain fatty acid catabolic process	--
ENSG00000158220	0.057	0.044	0.187	0.099	0.218	0.286	7	4	9	9	11	13	ESYT3	extended synaptotagmin 3 [Source:HGNC Symbol;Acc:HGNC:24295]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044232//organelle membrane contact site;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	GO:0006869//lipid transport;GO:0061817//endoplasmic reticulum-plasma membrane tethering	--
ENSG00000158234	6.042	5.8	7.663	5.694	5.84	8.136	112	109	111	86	100	103	FAIM	Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0050769//positive regulation of neurogenesis;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000158246	2.004	1.832	2.028	1.721	1.557	2.587	99	91	74	63	65	93	TENT5B	terminal nucleotidyltransferase 5B [Source:HGNC Symbol;Acc:HGNC:28273]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:1990817//RNA adenylyltransferase activity	GO:0008285//negative regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045727//positive regulation of translation;GO:0045786//negative regulation of cell cycle;GO:0048255//mRNA stabilization	--
ENSG00000158258	17.659	17.14	18.955	16.544	18.491	19.567	5202	5075	4124	3610	4602	4194	CLSTN2	calsyntenin 2 [Source:HGNC Symbol;Acc:HGNC:17448]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0001540//amyloid-beta binding;GO:0005509//calcium ion binding;GO:0019894//kinesin binding;GO:0042988//X11-like protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050806//positive regulation of synaptic transmission;GO:0051965//positive regulation of synapse assembly	--
ENSG00000158270	120.495	113.778	112.08	98.38	104.499	115.192	14306	13578	9828	8652	10482	9951	COLEC12	collectin subfamily member 12 [Source:HGNC Symbol;Acc:HGNC:16016]	Cellular Processes	Transport and catabolism	ko04145//Phagosome	K10062	GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane;GO:0031012//extracellular matrix	GO:0005044//scavenger receptor activity;GO:0005534//galactose binding;GO:0030169//low-density lipoprotein particle binding;GO:0030246//carbohydrate binding;GO:0038187//pattern recognition receptor activity;GO:0046872//metal ion binding	"GO:0006910//phagocytosis, recognition;GO:0006952//defense response;GO:0006955//immune response;GO:0009756//carbohydrate mediated signaling;GO:0034138//toll-like receptor 3 signaling pathway;GO:0042742//defense response to bacterium;GO:0044857//plasma membrane raft organization;GO:0045087//innate immune response;GO:0071360//cellular response to exogenous dsRNA"	--
ENSG00000158286	1.671	1.361	1.984	2.338	2.05	2.78	138	113	121	143	143	167	RNF207	ring finger protein 207 [Source:HGNC Symbol;Acc:HGNC:32947]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030544//Hsp70 protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0010628//positive regulation of gene expression;GO:0055117//regulation of cardiac muscle contraction;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:1901207//regulation of heart looping;GO:1902261//positive regulation of delayed rectifier potassium channel activity;GO:1903762//positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:1903954//positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	--
ENSG00000158290	15.127	12.425	10.817	10.327	11.9	12.265	1505	1196	810	782.02	983	843	CUL4B	cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555]	Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation;Replication and repair"	ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko03420//Nucleotide excision repair	K10609;K10609;K10609	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0070062//extracellular exosome;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031175//neuron projection development;GO:0034644//cellular response to UV;GO:0035518//histone H2A monoubiquitination;GO:0042254//ribosome biogenesis;GO:0045732//positive regulation of protein catabolic process;GO:0070914//UV-damage excision repair;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000158292	1.895	1.885	1.773	1.333	1.319	1.294	165	165	114	86	97	82	GPR153	G protein-coupled receptor 153 [Source:HGNC Symbol;Acc:HGNC:23618]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000158296	24.943	23.947	25.131	37.078	36.199	33.167	1840	1830	1316	2064	2287	1776	SLC13A3	solute carrier family 13 member 3 [Source:HGNC Symbol;Acc:HGNC:14430]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0005515//protein binding;GO:0015137//citrate transmembrane transporter activity;GO:0015139//alpha-ketoglutarate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015362//high-affinity sodium:dicarboxylate symporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0022857//transmembrane transporter activity;GO:0034634//glutathione transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006835//dicarboxylic acid transport;GO:0015742//alpha-ketoglutarate transport;GO:0015746//citrate transport;GO:0034775//glutathione transmembrane transport;GO:0055085//transmembrane transport;GO:0071422//succinate transmembrane transport;GO:0098656//anion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000158301	10.321	12.649	10.72	10.749	10.175	10.142	751.85	933.96	582.84	584.64	629.63	540	GPRASP2	G protein-coupled receptor associated sorting protein 2 [Source:HGNC Symbol;Acc:HGNC:25169]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0001540//amyloid-beta binding;GO:0001664//G protein-coupled receptor binding;GO:0005515//protein binding	GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000158315	1.554	1.045	1.02	1.21	1.182	1.365	55	37	29	35	39	39	RHBDL2	rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000158321	10.138	8.109	6.598	5.926	6.216	5.555	733	714	417	382	489	402	AUTS2	activator of transcription and developmental regulator AUTS2 [Source:HGNC Symbol;Acc:HGNC:14262]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030426//growth cone;GO:0042995//cell projection	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0010592//positive regulation of lamellipodium assembly;GO:0031532//actin cytoskeleton reorganization;GO:0035022//positive regulation of Rac protein signal transduction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048675//axon extension;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0097484//dendrite extension;GO:2000620//positive regulation of histone H4-K16 acetylation	--
ENSG00000158352	0.519	1.011	0.716	0.68	0.656	0.59	109	167	92	79	98	79	SHROOM4	shroom family member 4 [Source:HGNC Symbol;Acc:HGNC:29215]	-	-	-	-	GO:0001725//stress fiber;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009898//cytoplasmic side of plasma membrane;GO:0009925//basal plasma membrane;GO:0015629//actin cytoskeleton;GO:0016324//apical plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0045159//myosin II binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007420//brain development;GO:0030036//actin cytoskeleton organization;GO:0050890//cognition	--
ENSG00000158373	2.633	2.947	4.457	2.965	3.038	5.578	37	44	48	31	42	53	H2BC5	H2B clustered histone 5 [Source:HGNC Symbol;Acc:HGNC:4747]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000158402	0.078	0.195	0.362	0.21	0.311	0.203	3	8	6	5	8	3	CDC25C	cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: viral;Cancer: overview;Cell growth and death;Cell growth and death;Endocrine system	ko05170//Human immunodeficiency virus 1 infection;ko05206//MicroRNAs in cancer;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K05867;K05867;K05867;K05867;K05867	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0050699//WW domain binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0007088//regulation of mitotic nuclear division;GO:0007283//spermatogenesis;GO:0008283//cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051301//cell division;GO:0110032//positive regulation of G2/MI transition of meiotic cell cycle;GO:1902751//positive regulation of cell cycle G2/M phase transition	--
ENSG00000158406	0.346	0.444	0.508	0.691	0.663	1.128	9	11	12	14	16	19	H4C8	H4 clustered histone 8 [Source:HGNC Symbol;Acc:HGNC:4788]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000158411	5.44	5.033	4.981	5.715	6.545	5.195	106	99	70	81	105	73	MITD1	microtubule interacting and trafficking domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25207]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0032091//negative regulation of protein binding;GO:0051301//cell division;GO:0061952//midbody abscission	--
ENSG00000158417	5.173	3.986	3.055	2.08	2.663	2.735	585.32	442.29	248.5	167.95	235.88	226.43	EIF5B	eukaryotic translation initiation factor 5B [Source:HGNC Symbol;Acc:HGNC:30793]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation	--
ENSG00000158423	1.692	1.722	1.673	0.951	0.898	0.697	53	51	36	16	24	17	RIBC1	RIB43A domain with coiled-coils 1 [Source:HGNC Symbol;Acc:HGNC:26537]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000158427	4.846	2.533	4.599	3.925	2.205	3.293	66.67	35	49	39.32	27.08	39	TMSB15B	thymosin beta 15B [Source:HGNC Symbol;Acc:HGNC:28612]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0003785//actin monomer binding	GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0030335//positive regulation of cell migration;GO:0042989//sequestering of actin monomers	--
ENSG00000158428	0	0.145	0.099	0.148	0	0	0	4	2	3	0	0	CATIP	ciliogenesis associated TTC17 interacting protein [Source:HGNC Symbol;Acc:HGNC:25062]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0030041//actin filament polymerization;GO:0044782//cilium organization	--
ENSG00000158435	14.778	14.668	14.426	16.472	16.928	17.831	752	760	521	619	714	648	CNOT11	CCR4-NOT transcription complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:25217]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030014//CCR4-NOT complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0031047//gene silencing by RNA	--
ENSG00000158445	0.382	0.396	0.424	0.378	0.438	0.268	71	59	43	69	70	48	KCNB1	potassium voltage-gated channel subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:6231]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0000149//SNARE binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015271//outward rectifier potassium channel activity;GO:0044325//transmembrane transporter binding;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding	GO:0001508//action potential;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007215//glutamate receptor signaling pathway;GO:0010701//positive regulation of norepinephrine secretion;GO:0031669//cellular response to nutrient levels;GO:0033605//positive regulation of catecholamine secretion;GO:0034765//regulation of ion transmembrane transport;GO:0042593//glucose homeostasis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0046676//negative regulation of insulin secretion;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071333//cellular response to glucose stimulus;GO:0071805//potassium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0090314//positive regulation of protein targeting to membrane;GO:0097623//potassium ion export across plasma membrane;GO:0098900//regulation of action potential;GO:1900454//positive regulation of long-term synaptic depression;GO:2000671//regulation of motor neuron apoptotic process	--
ENSG00000158457	5.979	6.209	5.287	5.823	6.149	6.04	366	382	239	264	318	269	TSPAN33	tetraspanin 33 [Source:HGNC Symbol;Acc:HGNC:28743]	-	-	-	-	GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0046930//pore complex;GO:0097197//tetraspanin-enriched microdomain	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0046931//pore complex assembly;GO:0051604//protein maturation;GO:0072659//protein localization to plasma membrane	--
ENSG00000158458	2.801	2.373	2.821	3.159	3.46	4.063	148	114	108	121	154	163	NRG2	neuregulin 2 [Source:HGNC Symbol;Acc:HGNC:7998]	Human Diseases;Environmental Information Processing;Human Diseases	Neurodegenerative disease;Signal transduction;Drug resistance: antineoplastic	ko05014//Amyotrophic lateral sclerosis;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K05456;K05456;K05456	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0035556//intracellular signal transduction;GO:0048513//animal organ development	--
ENSG00000158467	140.936	153.623	139.99	112.081	119.715	122.106	10798	12228	7701	7056	8654	6471	AHCYL2	adenosylhomocysteinase like 2 [Source:HGNC Symbol;Acc:HGNC:22204]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K01251;K01251	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle	GO:0004013//adenosylhomocysteinase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006730//one-carbon metabolic process;GO:0033353//S-adenosylmethionine cycle	--
ENSG00000158470	22.227	21.717	21.787	19.779	20.387	21.54	2177	2138	1576	1435	1687	1535	B4GALT5	"beta-1,4-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:928]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K09905;K09905	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0003945//N-acetyllactosamine synthase activity;GO:0008378//galactosyltransferase activity;GO:0008489//UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0010706//ganglioside biosynthetic process via lactosylceramide;GO:0016266//O-glycan processing;GO:0021955//central nervous system neuron axonogenesis;GO:0022010//central nervous system myelination;GO:0030311//poly-N-acetyllactosamine biosynthetic process;GO:0031647//regulation of protein stability;GO:0040019//positive regulation of embryonic development;GO:0042551//neuron maturation;GO:0070085//glycosylation	--
ENSG00000158473	0.045	0.042	0.036	0	0	0.041	3	3	2	0	0	2	CD1D	CD1d molecule [Source:HGNC Symbol;Acc:HGNC:1637]	Cellular Processes;Human Diseases;Organismal Systems	Cellular community - eukaryotes;Infectious disease: parasitic;Immune system	ko04530//Tight junction;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage	K06448;K06448;K06448	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0030882//lipid antigen binding;GO:0030883//endogenous lipid antigen binding;GO:0030884//exogenous lipid antigen binding;GO:0042393//histone binding;GO:0050839//cell adhesion molecule binding;GO:0071723//lipopeptide binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002376//immune system process;GO:0016045//detection of bacterium;GO:0034113//heterotypic cell-cell adhesion;GO:0042102//positive regulation of T cell proliferation;GO:0045058//T cell selection;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib"	--
ENSG00000158477	0	0	0	0	0	0	0	0	0	0	0	0	CD1A	CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634]	Cellular Processes;Human Diseases;Organismal Systems	Cellular community - eukaryotes;Infectious disease: parasitic;Immune system	ko04530//Tight junction;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage	K06448;K06448;K06448	GO:0005615//extracellular space;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0030883//endogenous lipid antigen binding;GO:0030884//exogenous lipid antigen binding;GO:0071723//lipopeptide binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib"	--
ENSG00000158480	4.627	4.734	5.021	4.266	4.813	4.802	388	399	311	265	341	293	SPATA2	spermatogenesis associated 2 [Source:HGNC Symbol;Acc:HGNC:14681]	Cellular Processes	Cell growth and death	ko04217//Necroptosis	K17595	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0044877//protein-containing complex binding;GO:1990381//ubiquitin-specific protease binding	GO:0007283//spermatogenesis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0012501//programmed cell death;GO:0050727//regulation of inflammatory response;GO:0060544//regulation of necroptotic process;GO:0070266//necroptotic process;GO:0070536//protein K63-linked deubiquitination;GO:0072520//seminiferous tubule development;GO:1990108//protein linear deubiquitination	--
ENSG00000158481	0	0	0	0	0	0	0	0	0	0	0	0	CD1C	CD1c molecule [Source:HGNC Symbol;Acc:HGNC:1636]	Cellular Processes;Human Diseases;Organismal Systems	Cellular community - eukaryotes;Infectious disease: parasitic;Immune system	ko04530//Tight junction;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage	K06448;K06448;K06448	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030883//endogenous lipid antigen binding;GO:0030884//exogenous lipid antigen binding;GO:0051861//glycolipid binding;GO:0071723//lipopeptide binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002376//immune system process;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib"	--
ENSG00000158485	0	0	0	0	0	0	0	0	0	0	0	0	CD1B	CD1b molecule [Source:HGNC Symbol;Acc:HGNC:1635]	Cellular Processes;Human Diseases;Organismal Systems	Cellular community - eukaryotes;Infectious disease: parasitic;Immune system	ko04530//Tight junction;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage	K06448;K06448;K06448	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030883//endogenous lipid antigen binding;GO:0030884//exogenous lipid antigen binding;GO:0071723//lipopeptide binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib"	--
ENSG00000158486	0.004	0.008	0.005	0	0	0	1	2	1	0	0	0	DNAH3	dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement;GO:0060285//cilium-dependent cell motility	--
ENSG00000158488	0	0	0	0	0	0	0	0	0	0	0	0	CD1E	CD1e molecule [Source:HGNC Symbol;Acc:HGNC:1638]	Cellular Processes;Human Diseases;Organismal Systems	Cellular community - eukaryotes;Infectious disease: parasitic;Immune system	ko04530//Tight junction;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage	K06448;K06448;K06448	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen	GO:0008289//lipid binding;GO:0030883//endogenous lipid antigen binding;GO:0030884//exogenous lipid antigen binding;GO:0071723//lipopeptide binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib"	--
ENSG00000158497	0	0	0	0	0	0	0	0	0	0	0	0	HMHB1	histocompatibility minor HB-1 [Source:HGNC Symbol;Acc:HGNC:29677]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0032729//positive regulation of interferon-gamma production;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000158516	0.362	0.289	0.344	0.147	0.343	0.1	10	8	7	3	8	2	CPA2	carboxypeptidase A2 [Source:HGNC Symbol;Acc:HGNC:2297]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01298;K01298	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005773//vacuole	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007039//protein catabolic process in the vacuole	--
ENSG00000158517	0	0	0	0	0.212	0	0	0	0	0	5	0	NCF1	neutrophil cytosolic factor 1 [Source:HGNC Symbol;Acc:HGNC:7660]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Immune system;Cancer: overview;Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Immune system;Immune system;Infectious disease: parasitic;Cardiovascular disease;Development and regeneration;Immune system	ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05140//Leishmaniasis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04670//Leukocyte transendothelial migration	K08011;K08011;K08011;K08011;K08011;K08011;K08011;K08011;K08011;K08011;K08011;K08011	GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030425//dendrite;GO:0032010//phagolysosome;GO:0043020//NADPH oxidase complex;GO:0043025//neuronal cell body	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0009055//electron transfer activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0017124//SH3 domain binding;GO:0035091//phosphatidylinositol binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	"GO:0006612//protein targeting to membrane;GO:0006801//superoxide metabolic process;GO:0006915//apoptotic process;GO:0006968//cellular defense response;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0022900//electron transport chain;GO:0034614//cellular response to reactive oxygen species;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0045730//respiratory burst;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0050790//regulation of catalytic activity;GO:0060264//regulation of respiratory burst involved in inflammatory response;GO:0071276//cellular response to cadmium ion;GO:1900745//positive regulation of p38MAPK cascade;GO:1903409//reactive oxygen species biosynthetic process"	--
ENSG00000158525	0	0	0.09	0	0	0	0	0	2	0	0	0	CPA5	carboxypeptidase A5 [Source:HGNC Symbol;Acc:HGNC:15722]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000158526	12.232	11.637	13.236	12.425	12.163	12.295	1034.15	988.92	826.49	778.12	868.8	756.3	TSR2	TSR2 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25455]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing"	--
ENSG00000158528	6.073	4.958	5.018	2.47	3.637	2.962	879	768	573	323	498	406	PPP1R9A	protein phosphatase 1 regulatory subunit 9A [Source:HGNC Symbol;Acc:HGNC:14946]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030425//dendrite;GO:0030864//cortical actin cytoskeleton;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007399//nervous system development;GO:0019722//calcium-mediated signaling;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0050804//modulation of chemical synaptic transmission	--
ENSG00000158545	12.805	12.645	13.416	12.992	14.252	12.364	937	920	714	702	886	663	ZC3H18	zinc finger CCCH-type containing 18 [Source:HGNC Symbol;Acc:HGNC:25091]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding;GO:0140262//mRNA cap binding complex binding	GO:0050779//RNA destabilization	--
ENSG00000158552	9.501	8.973	8.057	11.222	10.41	13.823	218	201	151	191	204	224	ZFAND2B	zinc finger AN1-type containing 2B [Source:HGNC Symbol;Acc:HGNC:25206]	-	-	-	-	GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding	"GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0045047//protein targeting to ER"	--
ENSG00000158553	0	0	0	0	0	0	0	0	0	0	0	0	POM121L2	POM121 transmembrane nucleoporin like 2 [Source:HGNC Symbol;Acc:HGNC:13973]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14316;K14316	GO:0005635//nuclear envelope;GO:0005643//nuclear pore	GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus	--
ENSG00000158555	79.991	84.375	92.614	111.967	105.558	108.166	5417	5587	4493	5442	6079	5373	GDPD5	glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0047389//glycerophosphocholine phosphodiesterase activity	GO:0006629//lipid metabolic process;GO:0007399//nervous system development;GO:0045666//positive regulation of neuron differentiation	--
ENSG00000158560	3.573	3.725	2.887	3.01	3.763	2.869	168	199	119	109	159	114	DYNC1I1	dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10415;K10415;K10415	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0031982//vesicle;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome"	GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0030507//spectrin binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0007018//microtubule-based movement;GO:0010970//transport along microtubule;GO:0047496//vesicle transport along microtubule	--
ENSG00000158571	0.239	0.121	0.145	0.096	0.028	0.083	7	4	3	2	1	2	PFKFB1	"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:8872]"	Metabolism;Environmental Information Processing;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04152//AMPK signaling pathway;ko04922//Glucagon signaling pathway;ko00051//Fructose and mannose metabolism	K19028;K19028;K19028;K19028	"GO:0005829//cytosol;GO:0043540//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex"	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003873//6-phosphofructo-2-kinase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0070095//fructose-6-phosphate binding"	"GO:0006000//fructose metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0016311//dephosphorylation;GO:0031100//animal organ regeneration;GO:0032868//response to insulin;GO:0033133//positive regulation of glucokinase activity;GO:0033762//response to glucagon;GO:0042594//response to starvation;GO:0046835//carbohydrate phosphorylation;GO:0051384//response to glucocorticoid;GO:0051591//response to cAMP"	--
ENSG00000158578	0	0	0	0	0	0	0	0	0	0	0	0	ALAS2	5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Amino acid metabolism	"ko01100//Metabolic pathways;ko00860//Porphyrin metabolism;ko00260//Glycine, serine and threonine metabolism"	K00643;K00643;K00643	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0003870//5-aminolevulinate synthase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding	GO:0001666//response to hypoxia;GO:0006778//porphyrin-containing compound metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0006879//cellular iron ion homeostasis;GO:0009058//biosynthetic process;GO:0030218//erythrocyte differentiation;GO:0032364//oxygen homeostasis;GO:0033014//tetrapyrrole biosynthetic process;GO:0042541//hemoglobin biosynthetic process;GO:0048821//erythrocyte development	--
ENSG00000158604	47.374	47.762	49.995	47.413	52.341	47.237	1988	2016	1577	1487	1875	1474	TMED4	transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	-	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000158615	10.347	9.081	10.881	8.242	9.528	12.741	1120	985	868	657	874	1004	PPP1R15B	protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951]	-	-	-	-	GO:0000164//protein phosphatase type 1 complex;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0001933//negative regulation of protein phosphorylation;GO:0006417//regulation of translation;GO:0006979//response to oxidative stress;GO:0006983//ER overload response;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0042542//response to hydrogen peroxide;GO:0070262//peptidyl-serine dephosphorylation;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	--
ENSG00000158623	11.354	12.769	12.986	10.718	10.437	9.662	738	834	623	516	573	457	COPG2	COPI coat complex subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:2237]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030426//growth cone;GO:0030663//COPI-coated vesicle membrane;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle	GO:0005198//structural molecule activity	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0072384//organelle transport along microtubule"	--
ENSG00000158636	7.451	6.668	6.679	4.722	5.848	5.812	593	641	384	297	432	343	EMSY	"EMSY transcriptional repressor, BRCA2 interacting [Source:HGNC Symbol;Acc:HGNC:18071]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus"	--
ENSG00000158639	0	0	0	0	0	0	0	0	0	0	0	0	PAGE5	PAGE family member 5 [Source:HGNC Symbol;Acc:HGNC:29992]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000158669	25.858	17.521	26.314	21.004	26.766	23.429	1682	1752	1400	1346	1586	1526	GPAT4	glycerol-3-phosphate acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:20880]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13506;K13506;K13506	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0102420//sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	GO:0002071//glandular epithelial cell maturation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0007595//lactation;GO:0008610//lipid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0030879//mammary gland development;GO:0040014//regulation of multicellular organism growth;GO:0046339//diacylglycerol metabolic process	--
ENSG00000158683	0.065	0.141	0.082	0	0.153	0.139	4	10	2	0	5	8	PKD1L1	"polycystin 1 like 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:18053]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034704//calcium channel complex;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0003127//detection of nodal flow;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport;GO:0070986//left/right axis specification;GO:0098609//cell-cell adhesion	--
ENSG00000158691	3.351	2.807	2.475	2.176	2.028	2.965	380	314	208	176	195	224	ZSCAN12	zinc finger and SCAN domain containing 12 [Source:HGNC Symbol;Acc:HGNC:13172]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000158710	80.577	87.934	70.383	58.365	56.174	56.141	2299	2519	1483	1233	1354	1165	TAGLN2	transgelin 2 [Source:HGNC Symbol;Acc:HGNC:11554]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0030855//epithelial cell differentiation	--
ENSG00000158711	2.42	1.73	2.803	1.51	1.522	2.125	402	371	331	228	267	330	ELK4	ETS transcription factor ELK4 [Source:HGNC Symbol;Acc:HGNC:3326]	Environmental Information Processing;Human Diseases;Human Diseases	Signal transduction;Cancer: overview;Infectious disease: viral	ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection	K04376;K04376;K04376	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070932//histone H3 deacetylation"	ETS
ENSG00000158714	0.133	0.01	0.042	0	0.106	0.334	8.6	0.65	2.02	0	3.2	5.46	SLAMF8	SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002336//B-1 B cell lineage commitment;GO:0010760//negative regulation of macrophage chemotaxis;GO:0033860//regulation of NAD(P)H oxidase activity;GO:0042742//defense response to bacterium;GO:0043549//regulation of kinase activity;GO:0045577//regulation of B cell differentiation;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0090027//negative regulation of monocyte chemotaxis;GO:0090383//phagosome acidification;GO:1902623//negative regulation of neutrophil migration;GO:2000509//negative regulation of dendritic cell chemotaxis	--
ENSG00000158715	0.313	0.41	0.443	0.211	0.168	0.059	22	29	23	11	10	3	SLC45A3	solute carrier family 45 member 3 [Source:HGNC Symbol;Acc:HGNC:8642]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05202//Transcriptional misregulation in cancer;ko05206//MicroRNAs in cancer	K15379;K15379	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008506//sucrose:proton symporter activity;GO:0022857//transmembrane transporter activity;GO:0051119//sugar transmembrane transporter activity	GO:0008645//hexose transmembrane transport;GO:0010907//positive regulation of glucose metabolic process;GO:0015770//sucrose transport;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0048713//regulation of oligodendrocyte differentiation;GO:0055085//transmembrane transport	--
ENSG00000158716	14.328	16.073	15.96	20.146	19.923	15.481	216	242	177	223	250	168	DUSP23	dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000158717	5.01	6.151	6.639	4.336	7.279	5.546	193	240	190	124	240	157	RNF166	ring finger protein 166 [Source:HGNC Symbol;Acc:HGNC:28856]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000158747	11.973	16.426	12.957	20.645	19.106	12.003	489.88	648.86	401.76	642	642	350	NBL1	"NBL1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:7650]"	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K19558	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0016015//morphogen activity;GO:0036122//BMP binding;GO:0042802//identical protein binding;GO:0048018//receptor ligand activity	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0009887//animal organ morphogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0035582//sequestering of BMP in extracellular matrix;GO:0038098//sequestering of BMP from receptor via BMP binding;GO:0045666//positive regulation of neuron differentiation;GO:0048263//determination of dorsal identity;GO:0048812//neuron projection morphogenesis;GO:0090027//negative regulation of monocyte chemotaxis	--
ENSG00000158748	0	0.05	0	0	0	0	0	4	0	0	0	0	HTR6	5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse	K04162;K04162;K04162;K04162	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004969//histamine receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0021795//cerebral cortex cell migration;GO:0032008//positive regulation of TOR signaling;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000158764	0.042	0.041	0	0	0.049	0	1	1	0	0	1	0	ITLN2	intelectin 2 [Source:HGNC Symbol;Acc:HGNC:20599]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding	-	--
ENSG00000158769	7.618	7.191	8.288	9.293	8.985	7.186	733.25	689.57	560.17	519.78	650.03	503.72	F11R	F11 receptor [Source:HGNC Symbol;Acc:HGNC:14685]	Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Cellular community - eukaryotes;Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04530//Tight junction;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K06089;K06089;K06089;K06089	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0070160//tight junction	GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	GO:0001817//regulation of cytokine production;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0008360//regulation of cell shape;GO:0030855//epithelial cell differentiation;GO:0031032//actomyosin structure organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0034260//negative regulation of GTPase activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035633//maintenance of blood-brain barrier;GO:0035683//memory T cell extravasation;GO:0043547//positive regulation of GTPase activity;GO:0046718//viral entry into host cell;GO:0050892//intestinal absorption;GO:0051493//regulation of cytoskeleton organization;GO:0051497//negative regulation of stress fiber assembly;GO:0071260//cellular response to mechanical stimulus;GO:0072659//protein localization to plasma membrane;GO:0090557//establishment of endothelial intestinal barrier;GO:0090559//regulation of membrane permeability;GO:0098609//cell-cell adhesion;GO:1901731//positive regulation of platelet aggregation;GO:1902396//protein localization to bicellular tight junction;GO:1903142//positive regulation of establishment of endothelial barrier;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000158773	11.527	12.679	13.359	12.901	10.89	14.844	408	436	346	334	317	353	USF1	upstream transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12593]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0001666//response to hypoxia;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009411//response to UV;GO:0019086//late viral transcription;GO:0032869//cellular response to insulin stimulus;GO:0042593//glucose homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045990//carbon catabolite regulation of transcription;GO:0051918//negative regulation of fibrinolysis;GO:0055088//lipid homeostasis"	bHLH
ENSG00000158786	0	0	0	0	0	0	0	0	0	0	0	0	PLA2G2F	phospholipase A2 group IIF [Source:HGNC Symbol;Acc:HGNC:30040]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0002376//immune system process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0042130//negative regulation of T cell proliferation;GO:0045087//innate immune response;GO:0050482//arachidonic acid secretion	--
ENSG00000158792	3.507	3.874	5.252	4.021	3.31	4.635	164	170	142	144	130	140	SPATA2L	spermatogenesis associated 2 like [Source:HGNC Symbol;Acc:HGNC:28393]	Cellular Processes	Cell growth and death	ko04217//Necroptosis	K17595	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000158793	11.583	12.325	13.133	12.871	10.937	13.64	367.94	389.75	307.92	304.26	295.76	316.48	NIT1	nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	"GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0110050//deaminated glutathione amidase activity"	GO:0006807//nitrogen compound metabolic process;GO:0043605//cellular amide catabolic process	--
ENSG00000158796	14.158	14.663	14.456	14.561	13.895	14.679	515.06	499.25	394.08	424.74	453.24	414.52	DEDD	death effector domain containing [Source:HGNC Symbol;Acc:HGNC:2755]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0042177//negative regulation of protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0046697//decidualization;GO:1901837//negative regulation of transcription of nucleolar large rRNA by RNA polymerase I	--
ENSG00000158805	3.068	2.531	3.075	2.677	3.976	2.288	207.98	171.18	155.31	131.25	194.01	114.18	ZNF276	zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0043229//intracellular organelle"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043035//chromatin insulator sequence binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000158806	0	0	0.119	0	0.052	0	0	0	2	0	1	0	NPM2	nucleophosmin/nucleoplasmin 2 [Source:HGNC Symbol;Acc:HGNC:7930]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0001824//blastocyst development;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007096//regulation of exit from mitosis;GO:0007338//single fertilization;GO:0009994//oocyte differentiation;GO:0045740//positive regulation of DNA replication;GO:0045836//positive regulation of meiotic nuclear division	--
ENSG00000158813	1.603	1.458	1.444	2.357	1.943	1.758	167	149	116	174	169	133	EDA	ectodysplasin A [Source:HGNC Symbol;Acc:HGNC:3157]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway	K05480;K05480	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045177//apical part of cell	GO:0005102//signaling receptor binding;GO:0005123//death receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0038177//death receptor agonist activity;GO:0048018//receptor ligand activity	GO:0001942//hair follicle development;GO:0006955//immune response;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0030154//cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043473//pigmentation;GO:0043588//skin development;GO:0048513//animal organ development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060662//salivary gland cavitation;GO:0060789//hair follicle placode formation;GO:0061153//trachea gland development;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000158815	0	0	0	0	0	0.05	0	0	0	0	0	1	FGF17	fibroblast growth factor 17 [Source:HGNC Symbol;Acc:HGNC:3673]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration	--
ENSG00000158816	0.101	0.042	0.072	0.021	0.079	0.043	17	8	7	3	9	6	VWA5B1	von Willebrand factor A domain containing 5B1 [Source:HGNC Symbol;Acc:HGNC:26538]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000158825	0	0	0	0	0.071	0	0	0	0	0	1	0	CDA	cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:1712]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K01489;K01489;K01489	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0001882//nucleoside binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0007166//cell surface receptor signaling pathway;GO:0008655//pyrimidine-containing compound salvage;GO:0009972//cytidine deamination;GO:0019858//cytosine metabolic process;GO:0030308//negative regulation of cell growth;GO:0044206//UMP salvage;GO:0045980//negative regulation of nucleotide metabolic process;GO:0046898//response to cycloheximide;GO:0071217//cellular response to external biotic stimulus	--
ENSG00000158828	55.379	56.233	59.16	61.902	55.475	58.48	3052	3115	2408	2527	2583	2345	PINK1	PTEN induced kinase 1 [Source:HGNC Symbol;Acc:HGNC:14581]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05012//Parkinson disease;ko04137//Mitophagy - animal	K05688;K05688;K05688;K05688	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0031307//integral component of mitochondrial outer membrane;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:0097413//Lewy body;GO:0097449//astrocyte projection	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0002020//protease binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0010857//calcium-dependent protein kinase activity;GO:0016301//kinase activity;GO:0016504//peptidase activator activity;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0043422//protein kinase B binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0106310//protein serine kinase activity;GO:1904841//TORC2 complex binding	"GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0001934//positive regulation of protein phosphorylation;GO:0002082//regulation of oxidative phosphorylation;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0010629//negative regulation of gene expression;GO:0010821//regulation of mitochondrion organization;GO:0010952//positive regulation of peptidase activity;GO:0016239//positive regulation of macroautophagy;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016567//protein ubiquitination;GO:0018105//peptidyl-serine phosphorylation;GO:0022904//respiratory electron transport chain;GO:0030097//hemopoiesis;GO:0031396//regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032148//activation of protein kinase B activity;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033603//positive regulation of dopamine secretion;GO:0033605//positive regulation of catecholamine secretion;GO:0034599//cellular response to oxidative stress;GO:0035307//positive regulation of protein dephosphorylation;GO:0035556//intracellular signal transduction;GO:0036289//peptidyl-serine autophosphorylation;GO:0038203//TORC2 signaling;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045727//positive regulation of translation;GO:0046329//negative regulation of JNK cascade;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0051881//regulation of mitochondrial membrane potential;GO:0051897//positive regulation of protein kinase B signaling;GO:0061136//regulation of proteasomal protein catabolic process;GO:0071456//cellular response to hypoxia;GO:0072655//establishment of protein localization to mitochondrion;GO:0072656//maintenance of protein location in mitochondrion;GO:0090141//positive regulation of mitochondrial fission;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090258//negative regulation of mitochondrial fission;GO:0097237//cellular response to toxic substance;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0099074//mitochondrion to lysosome transport;GO:1900407//regulation of cellular response to oxidative stress;GO:1901215//negative regulation of neuron death;GO:1901525//negative regulation of mitophagy;GO:1901727//positive regulation of histone deacetylase activity;GO:1902803//regulation of synaptic vesicle transport;GO:1902902//negative regulation of autophagosome assembly;GO:1902958//positive regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1903146//regulation of autophagy of mitochondrion;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1903214//regulation of protein targeting to mitochondrion;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:1903384//negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway;GO:1903751//negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:1903852//positive regulation of cristae formation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:1904544//positive regulation of free ubiquitin chain polymerization;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:1904881//cellular response to hydrogen sulfide;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2001171//positive regulation of ATP biosynthetic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000158850	22.474	22.168	24.229	27.003	27.253	29.41	954.98	923.97	750	840	961.84	901	B4GALT3	"beta-1,4-galactosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:926]"	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00514//Other types of O-glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K07968;K07968;K07968;K07968;K07968;K07968;K07968	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome;GO:0098791//Golgi apparatus subcompartment	"GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0008378//galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006682//galactosylceramide biosynthetic process;GO:0070085//glycosylation	--
ENSG00000158856	1.585	0.956	1.239	1.774	1.41	1.949	37	19	24	30	23	30	DMTN	dematin actin binding protein [Source:HGNC Symbol;Acc:HGNC:3382]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0014731//spectrin-associated cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0031095//platelet dense tubular network membrane;GO:0031253//cell projection membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030507//spectrin binding;GO:0043621//protein self-association;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0010591//regulation of lamellipodium assembly;GO:0010763//positive regulation of fibroblast migration;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0030194//positive regulation of blood coagulation;GO:0032956//regulation of actin cytoskeleton organization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0048821//erythrocyte development;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0051017//actin filament bundle assembly;GO:0051489//regulation of filopodium assembly;GO:0051693//actin filament capping;GO:0051895//negative regulation of focal adhesion assembly;GO:0065003//protein-containing complex assembly;GO:0070560//protein secretion by platelet;GO:0071277//cellular response to calcium ion;GO:0071320//cellular response to cAMP;GO:0090303//positive regulation of wound healing;GO:0090315//negative regulation of protein targeting to membrane;GO:0090527//actin filament reorganization;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901731//positive regulation of platelet aggregation;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000158859	0.404	0.245	0.22	0.2	0.198	0.193	82	50	33	30	34	26.02	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif 4 [Source:HGNC Symbol;Acc:HGNC:220]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0002020//protease binding;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization	--
ENSG00000158863	9.197	10.124	9.879	10.632	10.655	8.61	807	900	608	705	769	553	FHIP2B	FHF complex subunit HOOK interacting protein 2B [Source:HGNC Symbol;Acc:HGNC:16492]	-	-	-	-	-	-	-	--
ENSG00000158864	45.024	47.523	53.326	61.266	56.56	54.323	1534	1613	1345	1533	1620	1345	NDUFS2	NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935;K03935	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070469//respirasome	"GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0019826//oxygen sensor activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0048038//quinone binding;GO:0051287//NAD binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006979//response to oxidative stress;GO:0009060//aerobic respiration;GO:0022008//neurogenesis;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042063//gliogenesis;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0061351//neural precursor cell proliferation;GO:0071453//cellular response to oxygen levels"	--
ENSG00000158865	0	0	0	0	0.188	0	0	0	0	0	3	0	SLC5A11	solute carrier family 5 member 11 [Source:HGNC Symbol;Acc:HGNC:23091]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005412//glucose:sodium symporter activity;GO:0005515//protein binding;GO:0015166//polyol transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006915//apoptotic process;GO:0008643//carbohydrate transport;GO:0015798//myo-inositol transport;GO:0032409//regulation of transporter activity;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000158869	0.082	0	0	0	0.484	0	1	0	0	0	5	0	FCER1G	Fc fragment of IgE receptor Ig [Source:HGNC Symbol;Acc:HGNC:3611]	Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Infectious disease: bacterial;Signal transduction;Immune system;Immune system;Immune system;Signal transduction;Immune system;Immune disease	ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04664//Fc epsilon RI signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05310//Asthma	K07983;K07983;K07983;K07983;K07983;K07983;K07983;K07983	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032998//Fc-epsilon receptor I complex;GO:0033001//Fc-gamma receptor III complex;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019767//IgE receptor activity;GO:0019863//IgE binding;GO:0019864//IgG binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0002283//neutrophil activation involved in immune response;GO:0002292//T cell differentiation involved in immune response;GO:0002376//immune system process;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0010543//regulation of platelet activation;GO:0016064//immunoglobulin mediated immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030593//neutrophil chemotaxis;GO:0031623//receptor internalization;GO:0032753//positive regulation of interleukin-4 production;GO:0038094//Fc-gamma receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038156//interleukin-3-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050766//positive regulation of phagocytosis;GO:0071404//cellular response to low-density lipoprotein particle stimulus	--
ENSG00000158874	0	0	0	0	0	0	0	0	0	0	0	0	APOA2	apolipoprotein A2 [Source:HGNC Symbol;Acc:HGNC:601]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism	K08758;K08758	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0042627//chylomicron;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005102//signaling receptor binding;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008035//high-density lipoprotein particle binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0031072//heat shock protein binding;GO:0031210//phosphatidylcholine binding;GO:0034190//apolipoprotein receptor binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0055102//lipase inhibitor activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0070653//high-density lipoprotein particle receptor binding;GO:0120020//cholesterol transfer activity	GO:0002526//acute inflammatory response;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0006641//triglyceride metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0009395//phospholipid catabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010873//positive regulation of cholesterol esterification;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0018158//protein oxidation;GO:0018206//peptidyl-methionine modification;GO:0030300//regulation of intestinal cholesterol absorption;GO:0030301//cholesterol transport;GO:0031100//animal organ regeneration;GO:0031647//regulation of protein stability;GO:0032375//negative regulation of cholesterol transport;GO:0032757//positive regulation of interleukin-8 production;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034380//high-density lipoprotein particle assembly;GO:0034384//high-density lipoprotein particle clearance;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0043627//response to estrogen;GO:0043691//reverse cholesterol transport;GO:0046340//diacylglycerol catabolic process;GO:0050766//positive regulation of phagocytosis;GO:0050821//protein stabilization;GO:0050995//negative regulation of lipid catabolic process;GO:0050996//positive regulation of lipid catabolic process;GO:0051384//response to glucocorticoid;GO:0060192//negative regulation of lipase activity;GO:0060621//negative regulation of cholesterol import;GO:0060695//negative regulation of cholesterol transporter activity;GO:0120009//intermembrane lipid transfer	--
ENSG00000158882	7.299	5.745	9.056	7.753	7.666	9.759	399.98	316	370.67	314	355	390	TOMM40L	translocase of outer mitochondrial membrane 40 like [Source:HGNC Symbol;Acc:HGNC:25756]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K11518;K11518	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0046930//pore complex	GO:0003674//molecular_function;GO:0008320//protein transmembrane transporter activity;GO:0015288//porin activity;GO:0030943//mitochondrion targeting sequence binding;GO:0070678//preprotein binding	GO:0006811//ion transport;GO:0008150//biological_process;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0055085//transmembrane transport	--
ENSG00000158887	0.026	0.184	0.077	0.102	0.031	0	1	7	2	2	1	0	MPZ	myelin protein zero [Source:HGNC Symbol;Acc:HGNC:7225]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06770	GO:0005764//lysosome;GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043209//myelin sheath;GO:0045202//synapse	GO:0005198//structural molecule activity	GO:0007268//chemical synaptic transmission;GO:0042552//myelination;GO:0043066//negative regulation of apoptotic process;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0098743//cell aggregation	--
ENSG00000158901	0	0	0	0	0	0	0	0	0	0	0	0	WFDC8	WAP four-disulfide core domain 8 [Source:HGNC Symbol;Acc:HGNC:16163]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0043086//negative regulation of catalytic activity;GO:0052547//regulation of peptidase activity	--
ENSG00000158941	27.299	28.833	32.433	34.819	35.308	41.523	2004	2170	1835	1658	1897	1780	CCAR2	cell cycle and apoptosis regulator 2 [Source:HGNC Symbol;Acc:HGNC:23360]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0044609//DBIRD complex	GO:0000993//RNA polymerase II complex binding;GO:0003723//RNA binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030374//nuclear receptor coactivator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0009411//response to UV;GO:0016055//Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0031647//regulation of protein stability;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0042752//regulation of circadian rhythm;GO:0043065//positive regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090311//regulation of protein deacetylation;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:2000003//positive regulation of DNA damage checkpoint"	--
ENSG00000158955	0.072	0.047	0.089	0.065	0.023	0.109	5	4	5	5	2	8	WNT9B	Wnt family member 9B [Source:HGNC Symbol;Acc:HGNC:12779]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064;K01064	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0039706//co-receptor binding;GO:0048018//receptor ligand activity	"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0001932//regulation of protein phosphorylation;GO:0003339//regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0007275//multicellular organism development;GO:0009267//cellular response to starvation;GO:0009786//regulation of asymmetric cell division;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030539//male genitalia development;GO:0032526//response to retinoic acid;GO:0035150//regulation of tube size;GO:0043085//positive regulation of catalytic activity;GO:0045165//cell fate commitment;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060021//roof of mouth development;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060993//kidney morphogenesis;GO:0061038//uterus morphogenesis;GO:0061303//cornea development in camera-type eye;GO:0071300//cellular response to retinoic acid;GO:0072003//kidney rudiment formation;GO:0072038//mesenchymal stem cell maintenance involved in nephron morphogenesis;GO:0072044//collecting duct development;GO:0072046//establishment of planar polarity involved in nephron morphogenesis;GO:0072078//nephron tubule morphogenesis;GO:0072164//mesonephric tubule development;GO:0072170//metanephric tubule development;GO:0072174//metanephric tubule formation;GO:0072181//mesonephric duct formation;GO:1902455//negative regulation of stem cell population maintenance;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1905438//non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation"	--
ENSG00000158966	12.575	12.528	10.76	7.882	8.523	10.705	1446	1475	908	686	842	896	CACHD1	cache domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29314]	-	-	-	-	GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005245//voltage-gated calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000158985	13.82	12.667	14.278	12.954	12.835	13.763	1054	974	805	728	837	773	CDC42SE2	CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547]	-	-	-	-	GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0035591//signaling adaptor activity	GO:0006909//phagocytosis;GO:0008360//regulation of cell shape;GO:0009966//regulation of signal transduction;GO:0035023//regulation of Rho protein signal transduction	--
ENSG00000158987	3.736	2.901	3.488	1.901	1.969	2.507	624	444	335.68	224	282.23	299.53	RAPGEF6	Rap guanine nucleotide exchange factor 6 [Source:HGNC Symbol;Acc:HGNC:20655]	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04015//Rap1 signaling pathway;ko04530//Tight junction	K08020;K08020	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding;GO:0070300//phosphatidic acid binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0030033//microvillus assembly;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0072659//protein localization to plasma membrane	--
ENSG00000159023	9.433	9.085	8.535	6.869	7.561	9.004	1012.57	924.94	646.98	503.66	668.11	688.13	EPB41	erythrocyte membrane protein band 4.1 [Source:HGNC Symbol;Acc:HGNC:3377]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014731//spectrin-associated cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0030863//cortical cytoskeleton;GO:0032991//protein-containing complex;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005545//1-phosphatidylinositol binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0030507//spectrin binding;GO:0047485//protein N-terminus binding;GO:0051219//phosphoprotein binding	GO:0007049//cell cycle;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0032092//positive regulation of protein binding;GO:0051301//cell division;GO:0051924//regulation of calcium ion transport;GO:1904478//regulation of intestinal absorption;GO:1904778//positive regulation of protein localization to cell cortex	--
ENSG00000159055	1.809	2.172	2.027	2.526	1.882	2.957	58	70	48	60	51	69	MIS18A	MIS18 kinetochore protein A [Source:HGNC Symbol;Acc:HGNC:1286]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0034080//CENP-A containing nucleosome assembly;GO:0044030//regulation of DNA methylation;GO:0051301//cell division	--
ENSG00000159063	32.32	31.681	33.196	39.431	35.414	39.131	1096	1081	843	992	1028	980	ALG8	"ALG8 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23161]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K03849;K03849	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0004583//dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0042283//dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0097502//mannosylation	--
ENSG00000159069	41.453	40.387	42.713	49.143	45.38	46.327	1980	1931	1502	1733	1825	1605	FBXW5	F-box and WD repeat domain containing 5 [Source:HGNC Symbol;Acc:HGNC:13613]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0000209//protein polyubiquitination;GO:0007088//regulation of mitotic nuclear division;GO:0010824//regulation of centrosome duplication;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043687//post-translational protein modification	--
ENSG00000159079	14.855	16.331	18.537	16.528	16.505	14.47	435.05	466.62	388.64	357.64	404.93	309.7	CFAP298	cilia and flagella associated protein 298 [Source:HGNC Symbol;Acc:HGNC:1301]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003352//regulation of cilium movement;GO:0060271//cilium assembly	--
ENSG00000159082	3.553	3.296	3.691	3.516	3.863	3.885	510	421	339	330	429	401	SYNJ1	synaptojanin 1 [Source:HGNC Symbol;Acc:HGNC:11503]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K20279;K20279;K20279	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0012506//vesicle membrane;GO:0030117//membrane coat;GO:0030132//clathrin coat of coated pit;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098793//presynapse	"GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0044877//protein-containing complex binding;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:1990175//EH domain binding"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006836//neurotransmitter transport;GO:0006897//endocytosis;GO:0007420//brain development;GO:0007612//learning;GO:0014015//positive regulation of gliogenesis;GO:0016082//synaptic vesicle priming;GO:0016191//synaptic vesicle uncoating;GO:0019637//organophosphate metabolic process;GO:0032526//response to retinoic acid;GO:0034097//response to cytokine;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0048489//synaptic vesicle transport;GO:0061024//membrane organization;GO:1904980//positive regulation of endosome organization	--
ENSG00000159086	6.072	4.822	4.816	4.626	5.225	6.322	441	355	262	191	319	329	PAXBP1	PAX3 and PAX7 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13579]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0003677//DNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0007517//muscle organ development;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000288//positive regulation of myoblast proliferation"	GCFC
ENSG00000159110	5.796	5.375	4.534	5.055	6.27	5.059	231.5	208.78	133	143	179.95	155.28	IFNAR2	interferon alpha and beta receptor subunit 2 [Source:HGNC Symbol;Acc:HGNC:5433]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04620//Toll-like receptor signaling pathway	K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0004905//type I interferon receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019962//type I interferon binding	GO:0007166//cell surface receptor signaling pathway;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000159111	16.612	17.426	18.27	21.953	20.956	20.904	596	627	484	586	638	544	MRPL10	mitochondrial ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:14055]	Genetic Information Processing	Translation	ko03010//Ribosome	K02864	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000159128	33.748	35.377	34.715	27.923	30.16	30.288	1153	1171	889	690	849	738	IFNGR2	interferon gamma receptor 2 [Source:HGNC Symbol;Acc:HGNC:5440]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Signaling molecules and interaction;Infectious disease: bacterial;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: parasitic;Development and regeneration;Signal transduction;Immune system;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko04066//HIF-1 signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321//Inflammatory bowel disease	K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133;K05133	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0004896//cytokine receptor activity;GO:0004906//interferon-gamma receptor activity;GO:0005515//protein binding	GO:0001774//microglial cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0051607//defense response to virus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0098586//cellular response to virus;GO:1904783//positive regulation of NMDA glutamate receptor activity	--
ENSG00000159131	17.537	17.215	16.619	14.236	18.526	16.268	1029	1038	758	646	874	765	GART	"phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]"	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Nucleotide metabolism;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko01523//Antifolate resistance;ko00670//One carbon pool by folate	K11787;K11787;K11787;K11787	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004637//phosphoribosylamine-glycine ligase activity;GO:0004641//phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0004644//phosphoribosylglycinamide formyltransferase activity;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0016874//ligase activity;GO:0046872//metal ion binding"	GO:0003360//brainstem development;GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0006544//glycine metabolic process;GO:0008152//metabolic process;GO:0009058//biosynthetic process;GO:0009113//purine nucleobase biosynthetic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0021549//cerebellum development;GO:0021987//cerebral cortex development;GO:0034641//cellular nitrogen compound metabolic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0046084//adenine biosynthetic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000159140	38.578	33.648	34.78	24.416	30.651	29.974	5291	4894	3686	2560	3653	3271	SON	SON DNA and RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000226//microtubule cytoskeleton organization;GO:0000281//mitotic cytokinesis;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0043066//negative regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0051726//regulation of cell cycle"	Others
ENSG00000159147	5.615	6.982	6.298	5.17	4.095	5.002	216	252	172	142.31	133.85	131.43	DONSON	DNA replication fork stabilization factor DONSON [Source:HGNC Symbol;Acc:HGNC:2993]	-	-	-	-	GO:0005634//nucleus;GO:0005657//replication fork;GO:0030894//replisome	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0006260//DNA replication;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0033260//nuclear DNA replication;GO:0048478//replication fork protection	--
ENSG00000159164	13.561	12.038	12.614	10.555	11.066	13.001	1227	1093	846	710	849	857	SV2A	synaptic vesicle glycoprotein 2A [Source:HGNC Symbol;Acc:HGNC:20566]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06258	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0019901//protein kinase binding;GO:0022857//transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0006874//cellular calcium ion homeostasis;GO:0007268//chemical synaptic transmission;GO:0014052//regulation of gamma-aminobutyric acid secretion;GO:0016082//synaptic vesicle priming;GO:0055085//transmembrane transport	--
ENSG00000159166	1.704	0.848	2.062	0.585	1.402	1.061	62	43	48	21	47	35	LAD1	ladinin 1 [Source:HGNC Symbol;Acc:HGNC:6472]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0045296//cadherin binding	-	--
ENSG00000159167	3.962	4.176	2.998	3.705	3.846	3.141	277	309	146	181	240	166	STC1	stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001503//ossification;GO:0001886//endothelial cell morphogenesis;GO:0003421//growth plate cartilage axis specification;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007566//embryo implantation;GO:0010596//negative regulation of endothelial cell migration;GO:0014070//response to organic cyclic compound;GO:0030336//negative regulation of cell migration;GO:0033280//response to vitamin D;GO:0035988//chondrocyte proliferation;GO:0044070//regulation of anion transport;GO:0046697//decidualization;GO:0051926//negative regulation of calcium ion transport;GO:0060348//bone development;GO:0071320//cellular response to cAMP;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071456//cellular response to hypoxia;GO:0086004//regulation of cardiac muscle cell contraction;GO:0090280//positive regulation of calcium ion import;GO:1903403//negative regulation of renal phosphate excretion	--
ENSG00000159173	0.916	0.867	0.793	1.379	0.924	1.691	43	44	30	21	23	33	TNNI1	"troponin I1, slow skeletal type [Source:HGNC Symbol;Acc:HGNC:11945]"	-	-	-	-	GO:0005829//cytosol;GO:0005861//troponin complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0003009//skeletal muscle contraction;GO:0006936//muscle contraction;GO:0006942//regulation of striated muscle contraction;GO:0014883//transition between fast and slow fiber;GO:0030049//muscle filament sliding;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000159176	17.464	19.78	14.199	15.522	16.746	13.899	665	762	400	439	548	390	CSRP1	cysteine and glycine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2469]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008307//structural constituent of muscle;GO:0042805//actinin binding;GO:0046872//metal ion binding	GO:0030036//actin cytoskeleton organization;GO:0045214//sarcomere organization;GO:0060537//muscle tissue development;GO:0070527//platelet aggregation	--
ENSG00000159182	0	0	0	0	0	0	0	0	0	0	0	0	PRAC1	PRAC1 small nuclear protein [Source:HGNC Symbol;Acc:HGNC:30591]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	-	-	--
ENSG00000159184	0	0	0	0	0	0	0	0	0	0	0	0	HOXB13	homeobox B13 [Source:HGNC Symbol;Acc:HGNC:5112]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0002009//morphogenesis of an epithelium;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008544//epidermis development;GO:0009611//response to wounding;GO:0030850//prostate gland development;GO:0033574//response to testosterone;GO:0040008//regulation of growth;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060743//epithelial cell maturation involved in prostate gland development"	Homeobox
ENSG00000159189	0	0	0	0	0.345	0	0	0	0	0	7	0	C1QC	complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03988;K03988;K03988;K03988;K03988;K03988;K03988;K03988	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005602//complement component C1 complex;GO:0005615//extracellular space;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0062167//complement component C1q complex;GO:0072562//blood microparticle;GO:0098794//postsynapse	GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0030853//negative regulation of granulocyte differentiation;GO:0045087//innate immune response;GO:0045650//negative regulation of macrophage differentiation;GO:0098883//synapse pruning"	--
ENSG00000159197	0.5	0.678	0.861	0.184	0.592	0.187	11	15	14	3	11	3	KCNE2	potassium voltage-gated channel subfamily E regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:6242]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K04896	GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007568//aging;GO:0034765//regulation of ion transmembrane transport;GO:0043586//tongue development;GO:0060306//regulation of membrane repolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071466//cellular response to xenobiotic stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086009//membrane repolarization;GO:0086011//membrane repolarization during action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1901979//regulation of inward rectifier potassium channel activity;GO:1902159//regulation of cyclic nucleotide-gated ion channel activity;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:1903817//negative regulation of voltage-gated potassium channel activity;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000159199	32.468	29.698	34.182	42.247	36.572	39.974	399	368	314	388	385	356	ATP5MC1	ATP synthase membrane subunit c locus 1 [Source:HGNC Symbol;Acc:HGNC:841]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128;K02128	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015078//proton transmembrane transporter activity	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0016043//cellular component organization;GO:1902600//proton transmembrane transport	--
ENSG00000159200	19.723	21.734	21.883	18.546	19.793	20.583	1002	1118	811	700	851	764	RCAN1	regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040]	Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Endocrine system;Endocrine system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04921//Oxytocin signaling pathway;ko04919//Thyroid hormone signaling pathway	K17901;K17901;K17901	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0042802//identical protein binding	GO:0019722//calcium-mediated signaling;GO:0033173//calcineurin-NFAT signaling cascade;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade	--
ENSG00000159202	33.272	33.258	35.536	31.954	33.327	38.791	2089	2098	1611	1470	1731	1771	UBE2Z	ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10585	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0010951//negative regulation of endopeptidase activity;GO:0016567//protein ubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process	--
ENSG00000159208	2.494	2.409	1.846	1.465	1.72	3.221	61	64	34	26	38	52	CIART	circadian associated repressor of transcription [Source:HGNC Symbol;Acc:HGNC:25200]	-	-	-	-	GO:0005634//nucleus;GO:0016605//PML body	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0070888//E-box binding	"GO:0032922//circadian regulation of gene expression;GO:0045475//locomotor rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000159210	43.641	44.67	45.139	40.616	41.502	40.063	929	971	725	670	761	652	SNF8	SNF8 subunit of ESCRT-II [Source:HGNC Symbol;Acc:HGNC:17028]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12188	GO:0000814//ESCRT II complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016247//channel regulator activity;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0032456//endocytic recycling;GO:0036258//multivesicular body assembly;GO:0042176//regulation of protein catabolic process;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045022//early endosome to late endosome transport;GO:0045732//positive regulation of protein catabolic process;GO:0061635//regulation of protein complex stability;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:1903543//positive regulation of exosomal secretion;GO:1903772//regulation of viral budding via host ESCRT complex	--
ENSG00000159212	206.896	217.951	237.178	190.256	206.654	170.144	18004	19059	15244	12265	15195	10770	CLIC6	chloride intracellular channel 6 [Source:HGNC Symbol;Acc:HGNC:2065]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0070062//extracellular exosome	GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0031749//D2 dopamine receptor binding;GO:0031750//D3 dopamine receptor binding;GO:0031751//D4 dopamine receptor binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport	--
ENSG00000159214	5.39	5.375	5.81	4.472	3.833	4.297	153.8	144	126	93	93	98	CCDC24	coiled-coil domain containing 24 [Source:HGNC Symbol;Acc:HGNC:28688]	-	-	-	-	-	GO:0005515//protein binding	GO:0001835//blastocyst hatching	--
ENSG00000159216	3.59	3.903	2.396	2.902	3.583	2.338	458	469	205	235	343	183	RUNX1	RUNX family transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10471]	Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04530//Tight junction;ko04659//Th17 cell differentiation;ko05220//Chronic myeloid leukemia;ko05221//Acute myeloid leukemia	K08367;K08367;K08367;K08367;K08367;K08367	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016513//core-binding factor complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0002062//chondrocyte differentiation;GO:0002573//myeloid leukocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010755//regulation of plasminogen activation;GO:0030097//hemopoiesis;GO:0030099//myeloid cell differentiation;GO:0030182//neuron differentiation;GO:0030854//positive regulation of granulocyte differentiation;GO:0032743//positive regulation of interleukin-2 production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0043371//negative regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048935//peripheral nervous system neuron development;GO:0051094//positive regulation of developmental process;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0061026//cardiac muscle tissue regeneration;GO:0071425//hematopoietic stem cell proliferation;GO:1903055//positive regulation of extracellular matrix organization;GO:1905203//regulation of connective tissue replacement"	Runt
ENSG00000159217	3.354	3.037	2.738	2.923	2.42	3.111	612	557	369	321	373	413	IGF2BP1	insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17391	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070937//CRD-mediated mRNA stability complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0045182//translation regulator activity;GO:0048027//mRNA 5'-UTR binding;GO:1990247//N6-methyladenosine-containing RNA binding	"GO:0001817//regulation of cytokine production;GO:0006403//RNA localization;GO:0006417//regulation of translation;GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0010610//regulation of mRNA stability involved in response to stress;GO:0017148//negative regulation of translation;GO:0022013//pallium cell proliferation in forebrain;GO:0051028//mRNA transport;GO:0051252//regulation of RNA metabolic process;GO:0070934//CRD-mediated mRNA stabilization;GO:0097150//neuronal stem cell population maintenance;GO:0140059//dendrite arborization;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000159224	0	0	0	0	0	0.093	0	0	0	0	0	1	GIP	gastric inhibitory polypeptide [Source:HGNC Symbol;Acc:HGNC:4270]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04911//Insulin secretion	K05258;K05258;K05258	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0034774//secretory granule lumen;GO:0043025//neuronal cell body	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031767//gastric inhibitory polypeptide receptor binding;GO:0031769//glucagon receptor binding	GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007565//female pregnancy;GO:0007613//memory;GO:0008344//adult locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0009743//response to carbohydrate;GO:0009749//response to glucose;GO:0010269//response to selenium ion;GO:0010447//response to acidic pH;GO:0010828//positive regulation of glucose transmembrane transport;GO:0014070//response to organic cyclic compound;GO:0019233//sensory perception of pain;GO:0031018//endocrine pancreas development;GO:0031667//response to nutrient levels;GO:0032024//positive regulation of insulin secretion;GO:0033993//response to lipid;GO:0035640//exploration behavior;GO:0038192//gastric inhibitory peptide signaling pathway;GO:0042304//regulation of fatty acid biosynthetic process;GO:0042594//response to starvation;GO:0043200//response to amino acid;GO:0043434//response to peptide hormone;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0048678//response to axon injury;GO:0050796//regulation of insulin secretion;GO:0050806//positive regulation of synaptic transmission;GO:0055123//digestive system development;GO:0060291//long-term synaptic potentiation;GO:0070094//positive regulation of glucagon secretion;GO:0070328//triglyceride homeostasis	--
ENSG00000159228	27.803	28.583	32.05	26.089	27.897	31.18	725	755	624	507	616	598	CBR1	carbonyl reductase 1 [Source:HGNC Symbol;Acc:HGNC:1548]	Metabolism;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Xenobiotics biodegradation and metabolism;Cancer: overview;Lipid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00590//Arachidonic acid metabolism;ko00790//Folate biosynthesis	K00079;K00079;K00079;K00079;K00079;K00079	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0047020//15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0047021//15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221//prostaglandin-E2 9-reductase activity"	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019371//cyclooxygenase pathway;GO:0030855//epithelial cell differentiation;GO:0042373//vitamin K metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000159231	0.193	0.336	0.131	0	0.114	0	4	7	2	0	2	0	CBR3	carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00590//Arachidonic acid metabolism	K00084;K00084;K00084	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0070402//NADPH binding"	GO:0006805//xenobiotic metabolic process;GO:0050890//cognition	--
ENSG00000159239	0.009	0.028	0.037	0	0.011	0	1.29	4.06	4	0	1.37	0	C2orf81	novel protein	-	-	-	-	-	-	-	--
ENSG00000159248	0.066	0.378	0.067	0.2	0.312	0.023	4	23	3	9	16	1	GJD2	gap junction protein delta 2 [Source:HGNC Symbol;Acc:HGNC:19154]	Cellular Processes	Cellular community - eukaryotes	ko04540//Gap junction	K07373	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005243//gap junction channel activity	GO:0001508//action potential;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007601//visual perception;GO:0055085//transmembrane transport	--
ENSG00000159251	15.908	20.13	2.74	11.02	18.21	9.301	456	580	58	234	441	194	ACTC1	actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K12314;K12314;K12314;K12314	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0005884//actin filament;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031674//I band;GO:0044297//cell body;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098978//glutamatergic synapse	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0017022//myosin binding	GO:0007015//actin filament organization;GO:0010628//positive regulation of gene expression;GO:0030048//actin filament-based movement;GO:0030240//skeletal muscle thin filament assembly;GO:0031032//actomyosin structure organization;GO:0033275//actin-myosin filament sliding;GO:0043066//negative regulation of apoptotic process;GO:0055003//cardiac myofibril assembly;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060047//heart contraction;GO:0070252//actin-mediated cell contraction;GO:0090131//mesenchyme migration	--
ENSG00000159256	5.033	3.974	3.06	2.358	2.864	3.498	441	350	198	153	212	223	MORC3	MORC family CW-type zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:23572]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016605//PML body	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016887//ATP hydrolysis activity;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	GO:0006468//protein phosphorylation;GO:0007569//cell aging;GO:0009791//post-embryonic development;GO:0018105//peptidyl-serine phosphorylation;GO:0048147//negative regulation of fibroblast proliferation;GO:0050821//protein stabilization;GO:0051457//maintenance of protein location in nucleus	--
ENSG00000159259	3.422	3.362	2.806	1.385	1.469	1.32	317	313	192	95	115	89	CHAF1B	chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0033186//CAF-1 complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0051082//unfolded protein binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031497//chromatin assembly	--
ENSG00000159261	0.039	0	0	0	0.046	0	1	0	0	0	1	0	CLDN14	claudin 14 [Source:HGNC Symbol;Acc:HGNC:2035]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0065003//protein-containing complex assembly;GO:0070830//bicellular tight junction assembly	--
ENSG00000159263	0	0	0	0	0	0	0	0	0	0	0	0	SIM2	SIM bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10883]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009880//embryonic pattern specification;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048731//system development"	bHLH
ENSG00000159267	10.738	9.875	9.671	7.422	7.602	7.926	1265	1169	826	680	804	674	HLCS	holocarboxylase synthetase [Source:HGNC Symbol;Acc:HGNC:4976]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00780//Biotin metabolism	K01942;K01942	GO:0000785//chromatin;GO:0005652//nuclear lamina;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016363//nuclear matrix	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004077//biotin-[acetyl-CoA-carboxylase] ligase activity;GO:0004078//biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity;GO:0004079//biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity;GO:0004080//biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0016874//ligase activity;GO:0018271//biotin-protein ligase activity;GO:0019899//enzyme binding	GO:0006464//cellular protein modification process;GO:0006768//biotin metabolic process;GO:0008152//metabolic process;GO:0009305//protein biotinylation;GO:0016570//histone modification;GO:0070781//response to biotin;GO:0071110//histone biotinylation	--
ENSG00000159289	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6A	golgin A6 family member A [Source:HGNC Symbol;Acc:HGNC:13567]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000159307	0.103	0.145	0.047	0.223	0.076	0.156	21	26	7	27	13	23	SCUBE1	"signal peptide, CUB domain and EGF like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13441]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007512//adult heart development;GO:0007596//blood coagulation;GO:0009791//post-embryonic development;GO:0045446//endothelial cell differentiation;GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000159314	0.518	0.377	0.6	0.443	0.512	0.502	25	29	31	24	33	28	ARHGAP27	Rho GTPase activating protein 27 [Source:HGNC Symbol;Acc:HGNC:31813]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000159322	28.824	29.843	29.319	29.662	28.034	29.306	1514	1579	1153	1166	1263	1144	ADPGK	ADP dependent glucokinase [Source:HGNC Symbol;Acc:HGNC:25250]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00010//Glycolysis / Gluconeogenesis	K08074;K08074;K08074	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0043843//ADP-specific glucokinase activity;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0016310//phosphorylation;GO:0061620//glycolytic process through glucose-6-phosphate	--
ENSG00000159335	62.494	66.559	72	69.702	67.76	75.166	1494	1601	1276	1240	1374	1314	PTMS	parathymosin [Source:HGNC Symbol;Acc:HGNC:9629]	-	-	-	-	GO:0005634//nucleus	GO:0042393//histone binding	GO:0002376//immune system process;GO:0006260//DNA replication;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000159337	0.011	0	0	0.031	0.013	0.016	1	0	0	2	1	1	PLA2G4D	phospholipase A2 group IVD [Source:HGNC Symbol;Acc:HGNC:30038]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008970//phospholipase A1 activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046475//glycerophospholipid catabolic process	--
ENSG00000159339	0	0	0	0	0	0	0	0	0	0	0	0	PADI4	peptidyl arginine deiminase 4 [Source:HGNC Symbol;Acc:HGNC:18368]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K24669	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0034618//arginine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006464//cellular protein modification process;GO:0018101//protein citrullination;GO:0019827//stem cell population maintenance;GO:0036413//histone H3-R26 citrullination;GO:0036414//histone citrullination;GO:0045087//innate immune response	--
ENSG00000159346	52.54	55.145	56.388	55.281	55.373	61.824	2260	2404	1794	1776	2029	1951	ADIPOR1	adiponectin receptor 1 [Source:HGNC Symbol;Acc:HGNC:24040]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine and metabolic disease;Signal transduction;Aging;Endocrine system	ko04932//Non-alcoholic fatty liver disease;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway	K07297;K07297;K07297;K07297;K07297	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0055100//adiponectin binding;GO:0097003//adipokinetic hormone receptor activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0010633//negative regulation of epithelial cell migration;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010906//regulation of glucose metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0019395//fatty acid oxidation;GO:0030308//negative regulation of cell growth;GO:0033210//leptin-mediated signaling pathway;GO:0033211//adiponectin-activated signaling pathway;GO:0042593//glucose homeostasis;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000159348	58.3	57.2	61.259	72.737	65.768	62.221	1952	1929	1512	1810	1864	1525	CYB5R1	cytochrome b5 reductase 1 [Source:HGNC Symbol;Acc:HGNC:13397]	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane;GO:0070062//extracellular exosome	"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0071949//FAD binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008202//steroid metabolic process;GO:0015701//bicarbonate transport;GO:0016126//sterol biosynthetic process	--
ENSG00000159352	49.666	52.294	52.08	52.812	47.22	44.147	1354	1439	1049	1071	1092	879	PSMD4	"proteasome 26S subunit ubiquitin receptor, non-ATPase 4 [Source:HGNC Symbol;Acc:HGNC:9561]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03029;K03029;K03029;K03029;K03029;K03029;K03029;K03029;K03029	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0022624//proteasome accessory complex"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000159363	37.61	39.159	38.86	39.993	39.354	36.653	2440	2688	1909	1976.2	2306	1699	ATP13A2	ATPase cation transporting 13A2 [Source:HGNC Symbol;Acc:HGNC:30213]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005776//autophagosome;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0032585//multivesicular body membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043202//lysosomal lumen;GO:1905103//integral component of lysosomal membrane	"GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0015417//ABC-type polyamine transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1903135//cupric ion binding"	GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis;GO:0006879//cellular iron ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0006914//autophagy;GO:0007041//lysosomal transport;GO:0010628//positive regulation of gene expression;GO:0010821//regulation of mitochondrion organization;GO:0016241//regulation of macroautophagy;GO:0016243//regulation of autophagosome size;GO:0030003//cellular cation homeostasis;GO:0033157//regulation of intracellular protein transport;GO:0034220//ion transmembrane transport;GO:0034599//cellular response to oxidative stress;GO:0046777//protein autophosphorylation;GO:0050714//positive regulation of protein secretion;GO:0052548//regulation of endopeptidase activity;GO:0055069//zinc ion homeostasis;GO:0055088//lipid homeostasis;GO:0061462//protein localization to lysosome;GO:0061909//autophagosome-lysosome fusion;GO:0071287//cellular response to manganese ion;GO:0071294//cellular response to zinc ion;GO:0097734//extracellular exosome biogenesis;GO:0098655//cation transmembrane transport;GO:1900180//regulation of protein localization to nucleus;GO:1901215//negative regulation of neuron death;GO:1902047//polyamine transmembrane transport;GO:1903146//regulation of autophagy of mitochondrion;GO:1903543//positive regulation of exosomal secretion;GO:1903710//spermine transmembrane transport;GO:1904714//regulation of chaperone-mediated autophagy;GO:1905037//autophagosome organization;GO:1905123//regulation of glucosylceramidase activity;GO:1905165//regulation of lysosomal protein catabolic process;GO:1905166//negative regulation of lysosomal protein catabolic process;GO:1990938//peptidyl-aspartic acid autophosphorylation;GO:2000152//regulation of ubiquitin-specific protease activity	--
ENSG00000159374	0.982	0.736	0.965	1.637	0.877	1.1	51	38	25	24	39	30	M1AP	meiosis 1 associated protein [Source:HGNC Symbol;Acc:HGNC:25183]	-	-	-	-	GO:0005737//cytoplasm;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006396//RNA processing;GO:0007127//meiosis I;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0030154//cell differentiation;GO:0031497//chromatin assembly;GO:0051308//male meiosis chromosome separation	--
ENSG00000159377	122.262	137.363	139.514	140.666	132.467	138.368	2328	2629	1962	1984	2131	1917	PSMB4	proteasome 20S subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:9541]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02736;K02736;K02736;K02736;K02736;K02736;K02736;K02736	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0036064//ciliary basal body;GO:0070062//extracellular exosome"	GO:0001530//lipopolysaccharide binding;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000159387	0	0	0	0	0	0	0	0	0	0	0	0	IRX6	iroquois homeobox 6 [Source:HGNC Symbol;Acc:HGNC:14675]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030182//neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development"	Homeobox
ENSG00000159388	14.38	14.196	13.563	14.477	13.259	12.601	814	804	567	607	626	519	BTG2	BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006479//protein methylation;GO:0006974//cellular response to DNA damage stimulus;GO:0008285//negative regulation of cell population proliferation;GO:0008306//associative learning;GO:0009612//response to mechanical stimulus;GO:0009952//anterior/posterior pattern specification;GO:0010033//response to organic substance;GO:0010243//response to organonitrogen compound;GO:0014070//response to organic cyclic compound;GO:0017148//negative regulation of translation;GO:0021542//dentate gyrus development;GO:0021954//central nervous system neuron development;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0035914//skeletal muscle cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043434//response to peptide hormone;GO:0043524//negative regulation of neuron apoptotic process;GO:0045930//negative regulation of mitotic cell cycle;GO:0051602//response to electrical stimulus;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000159398	0	0	0	0	0	0	0	0	0	0	0	0	CES5A	carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459]	-	-	-	-	GO:0005576//extracellular region	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0080030//methyl indole-3-acetate esterase activity	-	--
ENSG00000159399	4.962	5.286	3.248	4.315	5.853	3.604	579	618	279	373	577	304	HK2	hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: bacterial;Endocrine system;Signal transduction;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Biosynthesis of other secondary metabolites	"ko01100//Metabolic pathways;ko05131//Shigellosis;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00524//Neomycin, kanamycin and gentamicin biosynthesis"	K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004340//glucokinase activity;GO:0004396//hexokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008865//fructokinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019158//mannokinase activity"	GO:0001666//response to hypoxia;GO:0001678//cellular glucose homeostasis;GO:0002931//response to ischemia;GO:0005975//carbohydrate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0007595//lactation;GO:0008152//metabolic process;GO:0008637//apoptotic mitochondrial changes;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0035795//negative regulation of mitochondrial membrane permeability;GO:0045766//positive regulation of angiogenesis;GO:0046324//regulation of glucose import;GO:0046835//carbohydrate phosphorylation;GO:0051156//glucose 6-phosphate metabolic process;GO:0061621//canonical glycolysis;GO:0072655//establishment of protein localization to mitochondrion;GO:0072656//maintenance of protein location in mitochondrion;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000378//negative regulation of reactive oxygen species metabolic process	--
ENSG00000159403	920.426	988.541	954.377	817.817	838.209	876.756	36322.68	39155.59	27923.16	23513.01	28065.45	25503.67	C1R	complement C1r [Source:HGNC Symbol;Acc:HGNC:1246]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K01330;K01330;K01330;K01330;K01330;K01330	-	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response"	--
ENSG00000159409	0.009	0	0	0	0.031	0.012	1	0	0	0	3	1	CELF3	CUGBP Elav-like family member 3 [Source:HGNC Symbol;Acc:HGNC:11967]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0036002//pre-mRNA binding;GO:0097322//7SK snRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0030317//flagellated sperm motility;GO:0030575//nuclear body organization;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0098781//ncRNA transcription"	--
ENSG00000159423	19.349	23.097	23.636	34.632	32.264	29.017	1190	1390	1068	1556	1692	1289	ALDH4A1	aldehyde dehydrogenase 4 family member A1 [Source:HGNC Symbol;Acc:HGNC:406]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K00294;K00294;K00294	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0003842//1-pyrroline-5-carboxylate dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding"	GO:0006560//proline metabolic process;GO:0006562//proline catabolic process;GO:0010133//proline catabolic process to glutamate;GO:0019470//4-hydroxyproline catabolic process;GO:0022900//electron transport chain	--
ENSG00000159433	2.113	1.976	2.168	1.778	1.963	2.239	631	600	466	360	475	461	STARD9	StAR related lipid transfer domain containing 9 [Source:HGNC Symbol;Acc:HGNC:19162]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008289//lipid binding	GO:0007018//microtubule-based movement;GO:0051225//spindle assembly	--
ENSG00000159445	4.639	6.137	5.234	5.71	7.201	5.091	249	264	215	208	262	172	THEM4	thioesterase superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:17947]	Environmental Information Processing;Metabolism	Signal transduction;Lipid metabolism	ko04151//PI3K-Akt signaling pathway;ko00062//Fatty acid elongation	K16339;K16339	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006915//apoptotic process;GO:0043491//protein kinase B signaling;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process	--
ENSG00000159450	0	0	0	0	0	0	0	0	0	0	0	0	TCHH	trichohyalin [Source:HGNC Symbol;Acc:HGNC:11791]	-	-	-	-	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0008150//biological_process;GO:0031424//keratinization;GO:0045109//intermediate filament organization	--
ENSG00000159455	0	0	0	0	0	0	0	0	0	0	0	0	LCE2B	late cornified envelope 2B [Source:HGNC Symbol;Acc:HGNC:16610]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000159459	8.54	6.429	6.554	5.47	5.432	5.832	1233	1013	683	516	688	650	UBR1	ubiquitin protein ligase E3 component n-recognin 1 [Source:HGNC Symbol;Acc:HGNC:16808]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0070728//leucine binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0032007//negative regulation of TOR signaling;GO:0071233//cellular response to leucine;GO:0071596//ubiquitin-dependent protein catabolic process via the N-end rule pathway	--
ENSG00000159461	44.336	42.631	46.356	39.009	42.95	46.253	3254	3175	2538	2144	2698	2468	AMFR	autocrine motility factor receptor [Source:HGNC Symbol;Acc:HGNC:463]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10636	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030425//dendrite;GO:0030426//growth cone;GO:0032991//protein-containing complex;GO:0036513//Derlin-1 retrotranslocation complex;GO:0043025//neuronal cell body;GO:0044322//endoplasmic reticulum quality control compartment;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030674//protein-macromolecule adaptor activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0061630//ubiquitin protein ligase activity;GO:1904288//BAT3 complex binding;GO:1990381//ubiquitin-specific protease binding	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0007568//aging;GO:0007611//learning or memory;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032092//positive regulation of protein binding;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904380//endoplasmic reticulum mannose trimming;GO:2000638//regulation of SREBP signaling pathway	--
ENSG00000159479	11.953	14.883	13.443	15.077	14.352	18.422	443	588	368	433	445	495	MED8	mediator complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:19971]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000159495	0	0	0	0	0	0	0	0	0	0	0	0	TGM7	transglutaminase 7 [Source:HGNC Symbol;Acc:HGNC:30790]	-	-	-	-	-	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	GO:0018149//peptide cross-linking	--
ENSG00000159496	0.953	1.058	1.412	1.343	0.768	1.409	66	66	67	60	38	59	RGL4	ral guanine nucleotide dissociation stimulator like 4 [Source:HGNC Symbol;Acc:HGNC:31911]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko05210//Colorectal cancer;ko05212//Pancreatic cancer	K08732;K08732;K08732;K08732;K08732;K08732;K08732	GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000159516	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2G	small proline rich protein 2G [Source:HGNC Symbol;Acc:HGNC:11267]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000159527	0	0	0	0	0	0	0	0	0	0	0	0	PGLYRP3	peptidoglycan recognition protein 3 [Source:HGNC Symbol;Acc:HGNC:30014]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0016019//peptidoglycan immune receptor activity;GO:0042834//peptidoglycan binding;GO:0046982//protein heterodimerization activity	GO:0002376//immune system process;GO:0009253//peptidoglycan catabolic process;GO:0016045//detection of bacterium;GO:0031640//killing of cells of other organism;GO:0032689//negative regulation of interferon-gamma production;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0051701//biological process involved in interaction with host;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000159556	0	0	0	0.036	0	0.036	0	0	0	1	0	1	ISL2	ISL LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:18524]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007409//axonogenesis;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021524//visceral motor neuron differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:0045665//negative regulation of neuron differentiation;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048666//neuron development;GO:0048935//peripheral nervous system neuron development"	Homeobox
ENSG00000159579	18.151	16.177	16.338	14.853	13.608	16.023	1119	1085	712	670	752	717	RSPRY1	ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000159588	0	0	0.07	0	0	0.033	0	0	2	0	0	1	CCDC17	coiled-coil domain containing 17 [Source:HGNC Symbol;Acc:HGNC:26574]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000159592	14.049	14.364	14.662	11.667	12.635	14.757	1056	1087	813	650	802	807	GPBP1L1	GC-rich promoter binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28843]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	Others
ENSG00000159593	13.331	14.155	10.915	13.852	11.437	13.566	482	513	297	371	359	350	NAE1	NEDD8 activating enzyme E1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:621]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K04532	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0019781//NEDD8 activating enzyme activity;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0042981//regulation of apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0045116//protein neddylation;GO:0051402//neuron apoptotic process	--
ENSG00000159596	13.361	12.147	11.139	12.351	13.633	15.694	406	371	250	278	350	347	TMEM69	transmembrane protein 69 [Source:HGNC Symbol;Acc:HGNC:28035]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000159618	0.014	0	0	0	0	0	1	0	0	0	0	0	ADGRG5	adhesion G protein-coupled receptor G5 [Source:HGNC Symbol;Acc:HGNC:19010]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000159625	0.116	0.363	0.33	0.134	0.079	0.049	7	21	7	6	4	2	DRC7	dynein regulatory complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:25289]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030317//flagellated sperm motility;GO:0048870//cell motility	--
ENSG00000159640	0.071	0.196	0.301	0.245	0.217	0.14	7	18	15	10	8	5	ACE	angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cardiovascular disease;Infectious disease: parasitic;Cardiovascular disease;Endocrine system;Endocrine system	ko05171//Coronavirus disease - COVID-19;ko05415//Diabetic cardiomyopathy;ko05142//Chagas disease;ko05410//Hypertrophic cardiomyopathy;ko04924//Renin secretion;ko04614//Renin-angiotensin system	K01283;K01283;K01283;K01283;K01283;K01283	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece	GO:0003779//actin binding;GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0008241//peptidyl-dipeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0031404//chloride ion binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031711//bradykinin receptor binding;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:0070573//metallodipeptidase activity;GO:1901363//heterocyclic compound binding	GO:0001666//response to hypoxia;GO:0001822//kidney development;GO:0001974//blood vessel remodeling;GO:0002003//angiotensin maturation;GO:0002019//regulation of renal output by angiotensin;GO:0002446//neutrophil mediated immunity;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0007565//female pregnancy;GO:0007568//aging;GO:0008217//regulation of blood pressure;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009792//embryo development ending in birth or egg hatching;GO:0010608//posttranscriptional regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010815//bradykinin catabolic process;GO:0014910//regulation of smooth muscle cell migration;GO:0019229//regulation of vasoconstriction;GO:0019233//sensory perception of pain;GO:0030324//lung development;GO:0031100//animal organ regeneration;GO:0031667//response to nutrient levels;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032496//response to lipopolysaccharide;GO:0032943//mononuclear cell proliferation;GO:0034616//response to laminar fluid shear stress;GO:0035814//negative regulation of renal sodium excretion;GO:0042310//vasoconstriction;GO:0042447//hormone catabolic process;GO:0042755//eating behavior;GO:0043065//positive regulation of apoptotic process;GO:0043171//peptide catabolic process;GO:0045777//positive regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0046325//negative regulation of glucose import;GO:0048286//lung alveolus development;GO:0050435//amyloid-beta metabolic process;GO:0050482//arachidonic acid secretion;GO:0050729//positive regulation of inflammatory response;GO:0050769//positive regulation of neurogenesis;GO:0060047//heart contraction;GO:0060177//regulation of angiotensin metabolic process;GO:0060218//hematopoietic stem cell differentiation;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0071333//cellular response to glucose stimulus;GO:0071548//response to dexamethasone;GO:0071838//cell proliferation in bone marrow;GO:0090281//negative regulation of calcium ion import;GO:0097066//response to thyroid hormone;GO:0097746//blood vessel diameter maintenance;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:1903597//negative regulation of gap junction assembly;GO:1904045//cellular response to aldosterone;GO:2000170//positive regulation of peptidyl-cysteine S-nitrosylation	--
ENSG00000159648	0	0	0	0	0	0.046	0	0	0	0	0	1	TEPP	"testis, prostate and placenta expressed [Source:HGNC Symbol;Acc:HGNC:33745]"	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000159650	0.103	0.059	0.06	0	0.052	0	7	4	3	0	3	0	UROC1	urocanate hydratase 1 [Source:HGNC Symbol;Acc:HGNC:26444]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00340//Histidine metabolism	K01712;K01712	GO:0005829//cytosol	GO:0005515//protein binding;GO:0016153//urocanate hydratase activity;GO:0016829//lyase activity	GO:0006547//histidine metabolic process;GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate	--
ENSG00000159658	23.118	22.773	21.262	17.85	19.771	20.319	2744	2701	1854	1571	1986	1761	EFCAB14	EF-hand calcium binding domain 14 [Source:HGNC Symbol;Acc:HGNC:29051]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000159674	310.884	312.391	314.903	379.594	354.624	394.203	9588	9983	7539	8807	9472	8997	SPON2	spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0003823//antigen binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0002448//mast cell mediated immunity;GO:0007155//cell adhesion;GO:0008228//opsonization;GO:0032496//response to lipopolysaccharide;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042742//defense response to bacterium;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0050832//defense response to fungus;GO:0051607//defense response to virus;GO:0060907//positive regulation of macrophage cytokine production;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000159685	18.862	21.02	18.604	15.738	16.209	13.17	395	443	288	241	285	200	CHCHD6	coiled-coil-helix-coiled-coil-helix domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28184]	-	-	-	-	GO:0001401//SAM complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation	--
ENSG00000159692	58.857	61.113	71.667	76.609	63.259	81.285	2260	2217	1917	2080	2091	2152	CTBP1	C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04310//Wnt signaling pathway;ko05220//Chronic myeloid leukemia;ko04330//Notch signaling pathway	K04496;K04496;K04496;K04496	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	"GO:0001222//transcription corepressor binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0051287//NAD binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0019079//viral genome replication;GO:0030154//cell differentiation;GO:0031065//positive regulation of histone deacetylation;GO:0031507//heterochromatin assembly;GO:0035067//negative regulation of histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050872//white fat cell differentiation;GO:0051726//regulation of cell cycle;GO:0090241//negative regulation of histone H4 acetylation"	--
ENSG00000159708	0.071	0	0	0	0.041	0.031	3	0	0	0	1	1	LRRC36	leucine rich repeat containing 36 [Source:HGNC Symbol;Acc:HGNC:25615]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000159713	9.262	10.723	9.811	4.144	5.701	4.348	197	230	154	65	102	67	TPPP3	tubulin polymerization promoting protein family member 3 [Source:HGNC Symbol;Acc:HGNC:24162]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0097427//microtubule bundle	GO:0015631//tubulin binding	GO:0001578//microtubule bundle formation;GO:0007566//embryo implantation;GO:0032273//positive regulation of protein polymerization;GO:0046697//decidualization;GO:0046785//microtubule polymerization	--
ENSG00000159714	10.739	9.477	8.63	10.058	11.141	9.712	488	431	295	332	423	320	ZDHHC1	zinc finger DHHC-type containing 1 [Source:HGNC Symbol;Acc:HGNC:17916]	-	-	-	-	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0002230//positive regulation of defense response to virus by host;GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0032461//positive regulation of protein oligomerization;GO:0140374//antiviral innate immune response;GO:1905668//positive regulation of protein localization to endosome	--
ENSG00000159720	82.458	89.611	91.076	105.607	91.527	97.089	2668	2935	2203	2530	2496	2288	ATP6V0D1	ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Cancer: overview;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05203//Viral carcinogenesis;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146;K02146	"GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005813//centrosome;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030670//phagocytic vesicle membrane;GO:0032991//protein-containing complex;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0033181//plasma membrane proton-transporting V-type ATPase complex;GO:0043005//neuron projection;GO:0043679//axon terminus;GO:0070062//extracellular exosome"	"GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0007420//brain development;GO:0016241//regulation of macroautophagy;GO:0030030//cell projection organization;GO:0036295//cellular response to increased oxygen levels;GO:0060271//cilium assembly;GO:1902600//proton transmembrane transport	--
ENSG00000159723	0	0	0	0	0.115	0	0	0	0	0	1	0	AGRP	agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330]	Organismal Systems	Endocrine system	ko04920//Adipocytokine signaling pathway	K05231	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0043025//neuronal cell body	GO:0005102//signaling receptor binding;GO:0005184//neuropeptide hormone activity;GO:0031779//melanocortin receptor binding;GO:0070996//type 1 melanocortin receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0007623//circadian rhythm;GO:0007631//feeding behavior;GO:0008343//adult feeding behavior;GO:0009755//hormone-mediated signaling pathway;GO:0032868//response to insulin;GO:0042755//eating behavior;GO:0048571//long-day photoperiodism;GO:0060135//maternal process involved in female pregnancy;GO:0060259//regulation of feeding behavior;GO:2000253//positive regulation of feeding behavior	--
ENSG00000159733	0.41	0.317	0.84	0.759	0.608	0.995	35	27	50	48	43	55	ZFYVE28	zinc finger FYVE-type containing 28 [Source:HGNC Symbol;Acc:HGNC:29334]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0046872//metal ion binding	GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway	--
ENSG00000159753	0.195	0.099	0.302	0.115	0.286	0.178	14	8	20	7	11	12	CARMIL2	capping protein regulator and myosin 1 linker 2 [Source:HGNC Symbol;Acc:HGNC:27089]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0044354//macropinosome;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0044877//protein-containing complex binding	"GO:0007163//establishment or maintenance of cell polarity;GO:0010592//positive regulation of lamellipodium assembly;GO:0016477//cell migration;GO:0030011//maintenance of cell polarity;GO:0030335//positive regulation of cell migration;GO:0044319//wound healing, spreading of cells;GO:0051639//actin filament network formation;GO:0061339//establishment or maintenance of monopolar cell polarity;GO:0090091//positive regulation of extracellular matrix disassembly;GO:1900029//positive regulation of ruffle assembly;GO:1902745//positive regulation of lamellipodium organization;GO:2000813//negative regulation of barbed-end actin filament capping"	--
ENSG00000159761	1.14	2.343	2.208	3.164	2.823	1.546	30	59	36	52	55	22	C16orf86	chromosome 16 open reading frame 86 [Source:HGNC Symbol;Acc:HGNC:33755]	-	-	-	-	-	-	-	--
ENSG00000159763	0	0	0	0	0.395	0	0	0	0	0	4	0	PIP	prolactin induced protein [Source:HGNC Symbol;Acc:HGNC:8993]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0019864//IgG binding;GO:0042802//identical protein binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001895//retina homeostasis;GO:0002682//regulation of immune system process;GO:0006508//proteolysis;GO:0010628//positive regulation of gene expression;GO:0070233//negative regulation of T cell apoptotic process	--
ENSG00000159784	2.244	2.096	2.096	4.055	3.802	4.259	189	179	131	242	262	221	FAM131B	family with sequence similarity 131 member B [Source:HGNC Symbol;Acc:HGNC:22202]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000159788	4.8	4.974	4.98	5.583	5.445	4.496	507	520	368	418	465	348	RGS12	regulator of G protein signaling 12 [Source:HGNC Symbol;Acc:HGNC:9994]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000159792	33.636	34.466	37.744	43.91	40.153	42.862	2426	2508	2022	2350	2443	2257	PSKH1	protein serine kinase H1 [Source:HGNC Symbol;Acc:HGNC:9529]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0016310//phosphorylation	--
ENSG00000159840	40.147	43.274	43.891	49.297	48.676	43.301	1800	1977	1482	1671	1896	1456	ZYX	zyxin [Source:HGNC Symbol;Acc:HGNC:13200]	Cellular Processes	Cellular community - eukaryotes	ko04510//Focal adhesion	K06273	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0045335//phagocytic vesicle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0043149//stress fiber assembly;GO:0050727//regulation of inflammatory response;GO:0071346//cellular response to interferon-gamma	--
ENSG00000159842	295.293	311.61	345.41	346.189	333.958	361.415	23275.94	24212.97	19021	18478	21226	19338.97	ABR	ABR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:81]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0004674//protein serine/threonine kinase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050804//modulation of chemical synaptic transmission;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000159871	0	0	0	0.086	0	0	0	0	0	2	0	0	LYPD5	LY6/PLAUR domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26397]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	-	--
ENSG00000159873	12.383	12.283	12.786	10.037	11.819	11.773	1010	995	747	610	807	698	CCDC117	coiled-coil domain containing 117 [Source:HGNC Symbol;Acc:HGNC:26599]	-	-	-	-	GO:0072686//mitotic spindle	GO:0005515//protein binding	GO:0008284//positive regulation of cell population proliferation;GO:0045739//positive regulation of DNA repair	--
ENSG00000159882	1.48	1.53	1.276	1.031	2.827	1.228	126	118	73	65	114	76	ZNF230	zinc finger protein 230 [Source:HGNC Symbol;Acc:HGNC:13024]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000159884	11.438	11.848	14.038	15.142	14.945	13.656	267.39	288.17	252.29	264.7	275.91	237.65	CCDC107	coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000159885	2.489	2.693	2.259	1.628	2.132	2.346	76.37	81.46	55.86	40.37	54.71	57.14	ZNF222	zinc finger protein 222 [Source:HGNC Symbol;Acc:HGNC:13015]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000159899	6.061	5.068	6.776	5.423	5.043	7.014	447.97	398.95	353	324	351	366.98	NPR2	natriuretic peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:7944]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism	ko01100//Metabolic pathways;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism	K12324;K12324;K12324;K12324;K12324	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0001653//peptide receptor activity;GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0016941//natriuretic peptide receptor activity;GO:0017046//peptide hormone binding;GO:0042562//hormone binding;GO:0042802//identical protein binding	GO:0001503//ossification;GO:0006182//cGMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0008217//regulation of blood pressure;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0022414//reproductive process;GO:0035556//intracellular signal transduction;GO:0051447//negative regulation of meiotic cell cycle;GO:0060348//bone development;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:1900194//negative regulation of oocyte maturation	--
ENSG00000159905	0.278	0.16	0.062	0.186	0.308	0.25	13	7	2	6	9	9	ZNF221	zinc finger protein 221 [Source:HGNC Symbol;Acc:HGNC:13014]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000159915	1.102	1.217	0.704	0.912	0.523	0.678	64	50	28	21	19	25	ZNF233	zinc finger protein 233 [Source:HGNC Symbol;Acc:HGNC:30946]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000159917	1.795	1.868	1.568	1.134	1.36	0.771	79.44	81.56	61.67	32.05	47.4	37	ZNF235	zinc finger protein 235 [Source:HGNC Symbol;Acc:HGNC:12866]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000159921	5.9	5.121	6.955	5.175	6.231	5.937	577	549	464	389	508	419	GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [Source:HGNC Symbol;Acc:HGNC:23657]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K12409;K12409	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008761//UDP-N-acetylglucosamine 2-epimerase activity;GO:0009384//N-acylmannosamine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006045//N-acetylglucosamine biosynthetic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0007155//cell adhesion;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0046835//carbohydrate phosphorylation;GO:0071704//organic substance metabolic process	--
ENSG00000159958	0.123	0.11	0.116	0.133	0.102	0.118	10	9	7	8	7	7	TNFRSF13C	TNF receptor superfamily member 13C [Source:HGNC Symbol;Acc:HGNC:17755]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Immune disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04064//NF-kappa B signaling pathway;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production	K05151;K05151;K05151;K05151;K05151	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0038023//signaling receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0030890//positive regulation of B cell proliferation;GO:0031295//T cell costimulation;GO:0031296//B cell costimulation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation	--
ENSG00000159961	0	0	0	0	0	0	0	0	0	0	0	0	OR3A3	olfactory receptor family 3 subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:8284]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000160007	24.692	22.057	23.817	21.36	21.516	23.559	4492	4010	3218	2914	3311	3102	ARHGAP35	Rho GTPase activating protein 35 [Source:HGNC Symbol;Acc:HGNC:4591]	Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems	Cell motility;Cellular community - eukaryotes;Immune system;Immune system	ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04611//Platelet activation;ko04670//Leukocyte transendothelial migration	K05732;K05732;K05732;K05732	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005525//GTP binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0032794//GTPase activating protein binding;GO:0044877//protein-containing complex binding	"GO:0001843//neural tube closure;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008360//regulation of cell shape;GO:0010976//positive regulation of neuron projection development;GO:0016477//cell migration;GO:0021955//central nervous system neuron axonogenesis;GO:0030879//mammary gland development;GO:0030900//forebrain development;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0031668//cellular response to extracellular stimulus;GO:0032956//regulation of actin cytoskeleton organization;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043010//camera-type eye development;GO:0043116//negative regulation of vascular permeability;GO:0043547//positive regulation of GTPase activity;GO:0044319//wound healing, spreading of cells;GO:0045724//positive regulation of cilium assembly;GO:0050770//regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0097485//neuron projection guidance"	--
ENSG00000160013	0	0	0	0	0.027	0	0	0	0	0	1	0	PTGIR	prostaglandin I2 receptor [Source:HGNC Symbol;Acc:HGNC:9602]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Circulatory system;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation	K04263;K04263;K04263	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0016501//prostacyclin receptor activity	"GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus"	--
ENSG00000160014	96.952	93.681	98.096	103.155	103.587	87.393	3498	3405	2588	2745	3149	2342	CALM3	calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0031966//mitochondrial membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0034704//calcium channel complex;GO:0043005//neuron projection;GO:0043209//myelin sheath;GO:1902494//catalytic complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0010856//adenylate cyclase activator activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030234//enzyme regulator activity;GO:0030235//nitric-oxide synthase regulator activity;GO:0031432//titin binding;GO:0031800//type 3 metabotropic glutamate receptor binding;GO:0031997//N-terminal myristoylation domain binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0048306//calcium-dependent protein binding;GO:0050998//nitric-oxide synthase binding;GO:0072542//protein phosphatase activator activity;GO:0097718//disordered domain specific binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0001975//response to amphetamine;GO:0002027//regulation of heart rate;GO:0005513//detection of calcium ion;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0021762//substantia nigra development;GO:0031279//regulation of cyclase activity;GO:0031954//positive regulation of protein autophosphorylation;GO:0032465//regulation of cytokinesis;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0043388//positive regulation of DNA binding;GO:0050848//regulation of calcium-mediated signaling;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051412//response to corticosterone;GO:0051592//response to calcium ion;GO:0055117//regulation of cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090150//establishment of protein localization to membrane;GO:0090151//establishment of protein localization to mitochondrial membrane;GO:0098901//regulation of cardiac muscle cell action potential;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1901842//negative regulation of high voltage-gated calcium channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1905913//negative regulation of calcium ion export across plasma membrane;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000160049	15.154	15.818	16.512	15.578	15.351	16.272	1238	1236.36	883	896	1044	928	DFFA	DNA fragmentation factor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2772]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K02310	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0044183//protein folding chaperone;GO:0060703//deoxyribonuclease inhibitor activity	GO:0006309//apoptotic DNA fragmentation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0032076//negative regulation of deoxyribonuclease activity;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0061077//chaperone-mediated protein folding;GO:0070242//thymocyte apoptotic process;GO:1900118//negative regulation of execution phase of apoptosis;GO:1902511//negative regulation of apoptotic DNA fragmentation	--
ENSG00000160050	27.001	31.889	27.537	28.072	24.819	26.387	500	576	370	369	383	363	CCDC28B	coiled-coil domain containing 28B [Source:HGNC Symbol;Acc:HGNC:28163]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000160051	2.348	2.67	2.076	2.782	2.202	1.761	98	112	64	86	78	54	IQCC	IQ motif containing C [Source:HGNC Symbol;Acc:HGNC:25545]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000160055	5.595	5.372	4.55	6.055	4.658	5.681	135	132	84	109	105	94	TMEM234	transmembrane protein 234 [Source:HGNC Symbol;Acc:HGNC:28837]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000160058	18.035	16.674	20.817	17.71	16.68	22.235	1099	1071	875	841	939	938	BSDC1	BSD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25501]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000160062	2.356	1.767	1.739	1.193	1.162	1.546	177.23	138.12	111	69.68	99	102	ZBTB8A	zinc finger and BTB domain containing 8A [Source:HGNC Symbol;Acc:HGNC:24172]	-	-	-	-	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000160072	1.42	1.604	1.825	1.505	1.463	1.695	80.59	78.73	68.79	58.78	69.35	78.89	ATAD3B	ATPase family AAA domain containing 3B [Source:HGNC Symbol;Acc:HGNC:24007]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007005//mitochondrion organization	--
ENSG00000160075	62.335	60.968	61.713	65.908	62.03	62.657	1796	1810	1341	1442	1554	1327	SSU72	"SSU72 homolog, RNA polymerase II CTD phosphatase [Source:HGNC Symbol;Acc:HGNC:25016]"	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000160087	26.8	27.43	27.428	27.667	26.105	28.561	853	887	662	684	743	679	UBE2J2	ubiquitin conjugating enzyme E2 J2 [Source:HGNC Symbol;Acc:HGNC:19268]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K04554;K04554;K04554;K04554	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000160094	20.32	17.937	18.67	20.778	20.787	19.204	1011	950	738	713	888	745	ZNF362	zinc finger protein 362 [Source:HGNC Symbol;Acc:HGNC:18079]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K23480	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000160097	0.147	0.183	0.069	0.099	0.18	0.076	8	10	3	4	7	3	FNDC5	fibronectin type III domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20240]	-	-	-	-	GO:0005576//extracellular region;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008150//biological_process;GO:0014850//response to muscle activity;GO:0090336//positive regulation of brown fat cell differentiation	--
ENSG00000160111	45.58	53.259	52.137	54.895	57.983	39.915	6029	7202	5051	5383	6432	3954	CPAMD8	C3 and PZP like alpha-2-macroglobulin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23228]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001654//eye development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000160113	17.763	21.014	21.723	20.648	21.073	25.442	878	1044	793	756	880	915	NR2F6	nuclear receptor subfamily 2 group F member 6 [Source:HGNC Symbol;Acc:HGNC:7977]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0043153//entrainment of circadian clock by photoperiod;GO:0048666//neuron development;GO:0048856//anatomical structure development;GO:0050965//detection of temperature stimulus involved in sensory perception of pain"	RXR-like
ENSG00000160117	0.095	0.121	0.088	0.036	0.165	0.045	5	6	4	1	7	2	ANKLE1	ankyrin repeat and LEM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26812]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006281//DNA repair;GO:0006611//protein export from nucleus;GO:0006974//cellular response to DNA damage stimulus;GO:0045950//negative regulation of mitotic recombination;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1905453//regulation of myeloid progenitor cell differentiation;GO:1905456//regulation of lymphoid progenitor cell differentiation;GO:2001022//positive regulation of response to DNA damage stimulus	--
ENSG00000160124	3.989	6.104	4.826	4.532	5.618	4.44	40	70	40	37	57	35	MIX23	mitochondrial matrix import factor 23 [Source:HGNC Symbol;Acc:HGNC:31136]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	-	-	--
ENSG00000160131	8.1	6.383	7.498	5.702	6.139	8.379	760	606	507	391	495	575	VMA21	vacuolar ATPase assembly factor VMA21 [Source:HGNC Symbol;Acc:HGNC:22082]	-	-	-	-	GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding	GO:0043462//regulation of ATPase activity;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly	--
ENSG00000160145	2.816	4.072	2.049	3.42	3.021	1.95	346	335	169	202	233	189	KALRN	kalirin RhoGEF kinase [Source:HGNC Symbol;Acc:HGNC:4814]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0019898//extrinsic component of membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007528//neuromuscular junction development;GO:0007595//lactation;GO:0007613//memory;GO:0008344//adult locomotory behavior;GO:0016192//vesicle-mediated transport;GO:0016310//phosphorylation;GO:0035176//social behavior;GO:0035556//intracellular signal transduction;GO:0042711//maternal behavior;GO:0043547//positive regulation of GTPase activity;GO:0046959//habituation;GO:0048013//ephrin receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060125//negative regulation of growth hormone secretion;GO:0060137//maternal process involved in parturition;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000160161	4.064	4.886	4.166	5.113	5.219	4.844	354	428	268	330	384	307	CILP2	cartilage intermediate layer protein 2 [Source:HGNC Symbol;Acc:HGNC:24213]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	-	-	--
ENSG00000160179	25.339	26.726	29.342	33.764	34.782	32.077	1528	1670	1317	1535	1763	1431	ABCG1	ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]	Human Diseases;Environmental Information Processing	Cardiovascular disease;Membrane transport	ko05417//Lipid and atherosclerosis;ko02010//ABC transporters	K05679;K05679	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0015485//cholesterol binding;GO:0019534//toxin transmembrane transporter activity;GO:0034041//ABC-type sterol transporter activity;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0090554//phosphatidylcholine floppase activity;GO:0120020//cholesterol transfer activity;GO:0140328//floppase activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0010033//response to organic substance;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010872//regulation of cholesterol esterification;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0010888//negative regulation of lipid storage;GO:0030301//cholesterol transport;GO:0032367//intracellular cholesterol transport;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0033993//response to lipid;GO:0034204//lipid translocation;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034436//glycoprotein transport;GO:0042632//cholesterol homeostasis;GO:0042987//amyloid precursor protein catabolic process;GO:0043691//reverse cholesterol transport;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0050714//positive regulation of protein secretion;GO:0055085//transmembrane transport;GO:0055091//phospholipid homeostasis;GO:0071403//cellular response to high density lipoprotein particle stimulus;GO:0071702//organic substance transport;GO:0120009//intermembrane lipid transfer;GO:1901998//toxin transport;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000160180	0	0	0	0	0.505	0	0	0	0	0	4	0	TFF3	trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030141//secretory granule	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0010906//regulation of glucose metabolic process;GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000160181	0	0	0	0	0	0	0	0	0	0	0	0	TFF2	trefoil factor 2 [Source:HGNC Symbol;Acc:HGNC:11756]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0031723//CXCR4 chemokine receptor binding	GO:0030277//maintenance of gastrointestinal epithelium;GO:0060455//negative regulation of gastric acid secretion;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000160182	0	0	0	0	0.348	0	0	0	0	0	3	0	TFF1	trefoil factor 1 [Source:HGNC Symbol;Acc:HGNC:11755]	Organismal Systems	Endocrine system	ko04915//Estrogen signaling pathway	K22456	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0005975//carbohydrate metabolic process;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0010039//response to iron ion;GO:0030154//cell differentiation;GO:0030277//maintenance of gastrointestinal epithelium;GO:0035902//response to immobilization stress;GO:0043434//response to peptide hormone	--
ENSG00000160183	0.241	0.12	0.218	0.105	0.143	0.218	12	6	8	3	6	7	TMPRSS3	transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0017080//sodium channel regulator activity	GO:0006508//proteolysis;GO:0006883//cellular sodium ion homeostasis;GO:0006897//endocytosis;GO:0007605//sensory perception of sound	--
ENSG00000160185	0	0	0	0	0	0	0	0	0	0	0	0	UBASH3A	ubiquitin associated and SH3 domain containing A [Source:HGNC Symbol;Acc:HGNC:12462]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0050860//negative regulation of T cell receptor signaling pathway	--
ENSG00000160188	4.858	5.369	4.462	3.084	3.387	2.711	110	124	74	55	63	42	RSPH1	radial spoke head component 1 [Source:HGNC Symbol;Acc:HGNC:12371]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0001520//outer dense fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0072687//meiotic spindle	GO:0005515//protein binding	GO:0007286//spermatid development;GO:0035082//axoneme assembly;GO:0051321//meiotic cell cycle	--
ENSG00000160190	0.564	0.799	0.969	0.633	0.817	0.493	38	56	22	31	45	23	SLC37A1	solute carrier family 37 member 1 [Source:HGNC Symbol;Acc:HGNC:11024]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0015297//antiporter activity;GO:0022857//transmembrane transporter activity;GO:0061513//glucose 6-phosphate:inorganic phosphate antiporter activity	GO:0008643//carbohydrate transport;GO:0015760//glucose-6-phosphate transport;GO:0035435//phosphate ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000160191	4.067	2.272	3.314	2.893	2.963	3.614	162	91	100	83	98	100	PDE9A	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13761;K13761	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007165//signal transduction;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0019934//cGMP-mediated signaling;GO:0046068//cGMP metabolic process;GO:0046069//cGMP catabolic process	--
ENSG00000160193	2.335	3.087	3.379	3.792	3.569	3.178	102	134	109	118	126	101	WDR4	WD repeat domain 4 [Source:HGNC Symbol;Acc:HGNC:12756]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0043527//tRNA methyltransferase complex	GO:0005515//protein binding;GO:0008176//tRNA (guanine-N7-)-methyltransferase activity	GO:0006400//tRNA modification;GO:0006974//cellular response to DNA damage stimulus;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0036265//RNA (guanine-N7)-methylation;GO:0106004//tRNA (guanine-N7)-methylation	--
ENSG00000160194	2.163	2.753	2.931	2.529	2.488	2.253	241	307	240	206	238	177	NDUFV3	NADH:ubiquinone oxidoreductase subunit V3 [Source:HGNC Symbol;Acc:HGNC:7719]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944;K03944	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000160199	2.24	2.679	2.057	3.028	3.247	2.603	232	247	167	212	240	191	PKNOX1	PBX/knotted 1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9022]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0030097//hemopoiesis;GO:0030217//T cell differentiation;GO:0030218//erythrocyte differentiation;GO:0043010//camera-type eye development;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000160200	9.91	8.769	11.377	9.1	11.251	17.923	515.12	452.94	433.53	350.11	494.91	670.8	CBS	cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism"	K01697;K01697;K01697;K01697	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004122//cystathionine beta-synthase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0030170//pyridoxal phosphate binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050421//nitrite reductase (NO-forming) activity;GO:0070025//carbon monoxide binding;GO:0070026//nitric oxide binding;GO:0072341//modified amino acid binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0006535//cysteine biosynthetic process from serine;GO:0006563//L-serine metabolic process;GO:0006565//L-serine catabolic process;GO:0008152//metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0019344//cysteine biosynthetic process;GO:0019448//L-cysteine catabolic process;GO:0042262//DNA protection;GO:0043418//homocysteine catabolic process;GO:0050667//homocysteine metabolic process;GO:0070814//hydrogen sulfide biosynthetic process	--
ENSG00000160201	29.567	32.603	33.07	34.434	34.989	43.693	583.43	644.96	480.98	500.29	579.18	622.43	U2AF1	U2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNC:12453]	Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Transcription	ko05131//Shigellosis;ko03040//Spliceosome	K12836;K12836	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000160202	5.501	6.348	2.796	3.623	2.679	1.908	129.97	140.22	48.78	63.4	51.56	32.79	CRYAA	crystallin alpha A [Source:HGNC Symbol;Acc:HGNC:2388]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09541	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005198//structural molecule activity;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0007601//visual perception;GO:0032387//negative regulation of intracellular transport;GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization;GO:0050896//response to stimulus	--
ENSG00000160207	1.269	0.656	1.031	0.864	0.42	1.081	40	26	30	23	14	31	HSF2BP	heat shock transcription factor 2 binding protein [Source:HGNC Symbol;Acc:HGNC:5226]	-	-	-	-	GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006366//transcription by RNA polymerase II;GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0007283//spermatogenesis;GO:1990918//double-strand break repair involved in meiotic recombination	--
ENSG00000160208	9.769	9.011	9.924	7.396	8.889	8.116	1029	954	772	577	791	622	RRP1B	ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818]	-	-	-	-	"GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0001652//granular component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030687//preribosome, large subunit precursor;GO:0030688//preribosome, small subunit precursor"	GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0034260//negative regulation of GTPase activity;GO:0043065//positive regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0043923//positive regulation by host of viral transcription;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0098586//cellular response to virus	--
ENSG00000160209	16.069	17.476	17.777	19.386	20.486	18.981	2440	2635	1973	2147	2593	2052	PDXK	pyridoxal kinase [Source:HGNC Symbol;Acc:HGNC:8819]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00750//Vitamin B6 metabolism	K00868;K00868	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0008478//pyridoxal kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0030955//potassium ion binding;GO:0031402//sodium ion binding;GO:0031403//lithium ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006796//phosphate-containing compound metabolic process;GO:0009443//pyridoxal 5'-phosphate salvage;GO:0016310//phosphorylation;GO:0042816//vitamin B6 metabolic process	--
ENSG00000160211	18.45	19.742	17.504	19.685	19.82	19.508	679	728	469	539	603	477	G6PD	glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057]	Metabolism;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Global and overview maps;Cancer: overview;Metabolism of other amino acids;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko01200//Carbon metabolism;ko05230//Central carbon metabolism in cancer;ko00480//Glutathione metabolism;ko00030//Pentose phosphate pathway	K00036;K00036;K00036;K00036;K00036;K00036	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004345//glucose-6-phosphate dehydrogenase activity;GO:0005515//protein binding;GO:0005536//glucose binding;GO:0016491//oxidoreductase activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0050661//NADP binding"	"GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006098//pentose-phosphate shunt;GO:0006629//lipid metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006739//NADP metabolic process;GO:0006740//NADPH regeneration;GO:0006749//glutathione metabolic process;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0010041//response to iron(III) ion;GO:0010734//negative regulation of protein glutathionylation;GO:0014070//response to organic cyclic compound;GO:0019322//pentose biosynthetic process;GO:0019637//organophosphate metabolic process;GO:0021762//substantia nigra development;GO:0032094//response to food;GO:0034599//cellular response to oxidative stress;GO:0043249//erythrocyte maturation;GO:0043523//regulation of neuron apoptotic process;GO:0045471//response to ethanol;GO:0046390//ribose phosphate biosynthetic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:1904879//positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:2000378//negative regulation of reactive oxygen species metabolic process"	--
ENSG00000160213	163.804	180.201	207.541	242.572	192.776	221.387	2068	2274	1944	2258	2046	2034	CSTB	cystatin B [Source:HGNC Symbol;Acc:HGNC:2482]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0002020//protease binding;GO:0003723//RNA binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0008344//adult locomotory behavior;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0045861//negative regulation of proteolysis	--
ENSG00000160214	12.396	9.635	12.816	15.475	11.143	10.192	537	576	463	543	502	403	RRP1	ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785]	-	-	-	-	"GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0030688//preribosome, small subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing	--
ENSG00000160216	37.019	39.799	35.875	36.366	38.299	35.467	3767	4067	2626	2770	3289	2658	AGPAT3	1-acylglycerol-3-phosphate O-acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:326]	Metabolism;Environmental Information Processing;Metabolism;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13523;K13523;K13523;K13523	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042171//lysophosphatidic acid acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process	--
ENSG00000160218	9.975	9.11	9.527	10.026	9.228	9.948	1172.2	1084.39	839.84	831.42	933.11	863.73	TRAPPC10	trafficking protein particle complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:11868]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:1990071//TRAPPII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0034498//early endosome to Golgi transport;GO:0048193//Golgi vesicle transport;GO:0099022//vesicle tethering	--
ENSG00000160219	0.171	0.172	0.125	0.11	0.157	0.179	15	17	8	8	13	10	GAB3	GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515]	-	-	-	-	-	-	GO:0030225//macrophage differentiation	--
ENSG00000160221	2.98	2.897	2.825	1.663	1.752	2.37	61.31	59.42	44.17	24.5	29.82	39.89	GATD3	glutamine amidotransferase class 1 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1273]	-	-	-	-	GO:0005739//mitochondrion	-	-	--
ENSG00000160223	0.711	0.712	0.838	0.986	1.096	1.139	95.25	81.8	89.11	105.23	131.85	108.19	ICOSLG	inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04672//Intestinal immune network for IgA production	K06710;K06710	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001817//regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006952//defense response;GO:0006972//hyperosmotic response;GO:0007165//signal transduction;GO:0042104//positive regulation of activated T cell proliferation;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0050852//T cell receptor signaling pathway	--
ENSG00000160224	0	0	0	0	0	0	0	0	0	0	0	0	AIRE	autoimmune regulator [Source:HGNC Symbol;Acc:HGNC:360]	Genetic Information Processing;Human Diseases	"Folding, sorting and degradation;Immune disease"	ko04120//Ubiquitin mediated proteolysis;ko05340//Primary immunodeficiency	K10603;K10603	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0045182//translation regulator activity;GO:0046872//metal ion binding	"GO:0002458//peripheral T cell tolerance induction;GO:0002509//central tolerance induction to self antigen;GO:0006355//regulation of transcription, DNA-templated;GO:0006417//regulation of translation;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0032722//positive regulation of chemokine production;GO:0045060//negative thymic T cell selection;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0097536//thymus epithelium morphogenesis;GO:2000410//regulation of thymocyte migration"	SAND
ENSG00000160226	14.236	14.079	16.675	20.866	18.714	20.237	587	602	520	652	670	637	CFAP410	cilia and flagella associated protein 410 [Source:HGNC Symbol;Acc:HGNC:1260]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097733//photoreceptor cell cilium	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0007010//cytoskeleton organization;GO:0007224//smoothened signaling pathway;GO:0008360//regulation of cell shape;GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000160229	0.381	0.221	0.273	0.474	0.397	0.772	20.53	13.02	18.98	18	31.59	18.28	ZNF66	zinc finger protein 66 [Source:HGNC Symbol;Acc:HGNC:13135]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000160233	2.326	1.871	1.698	2.327	2.255	1.78	282	228	152	209	231	157	LRRC3	leucine rich repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:14965]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000160255	0.019	0.05	0.091	0.067	0.21	0.051	1	1	3	1	7	2	ITGB2	integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Transport and catabolism;Immune system;Infectious disease: parasitic;Infectious disease: bacterial;Immune disease;Signal transduction;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune system;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: parasitic	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko04650//Natural killer cell mediated cytotoxicity;ko05146//Amoebiasis;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04390//Hippo signaling pathway;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko04670//Leukocyte transendothelial migration;ko04610//Complement and coagulation cascades;ko05133//Pertussis;ko05134//Legionellosis;ko05144//Malaria	K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464;K06464	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034687//integrin alphaL-beta2 complex;GO:0034688//integrin alphaM-beta2 complex;GO:0034689//integrin alphaX-beta2 complex;GO:0035579//specific granule membrane;GO:0043235//receptor complex;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane;GO:1903561//extracellular vesicle	GO:0001540//amyloid-beta binding;GO:0001851//complement component C3b binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030369//ICAM-3 receptor activity;GO:0031072//heat shock protein binding;GO:0038023//signaling receptor activity;GO:0038024//cargo receptor activity;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	"GO:0001774//microglial cell activation;GO:0006898//receptor-mediated endocytosis;GO:0006909//phagocytosis;GO:0006911//phagocytosis, engulfment;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0030593//neutrophil chemotaxis;GO:0031623//receptor internalization;GO:0032930//positive regulation of superoxide anion generation;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0035987//endodermal cell differentiation;GO:0043113//receptor clustering;GO:0043315//positive regulation of neutrophil degranulation;GO:0045963//negative regulation of dopamine metabolic process;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0090314//positive regulation of protein targeting to membrane;GO:0097242//amyloid-beta clearance;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1901216//positive regulation of neuron death;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:1990266//neutrophil migration;GO:2000363//positive regulation of prostaglandin-E synthase activity"	--
ENSG00000160256	6.376	6.675	7.953	8.75	6.512	8.823	117	121	108	119	101	118	SLX9	SLX9 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:15811]	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030686//90S preribosome;GO:0030688//preribosome, small subunit precursor"	GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000160271	16.676	17.21	20.591	18.646	19.771	22.236	1244.44	1279.99	1096	1053.58	1206	1133	RALGDS	ral guanine nucleotide dissociation stimulator [Source:HGNC Symbol;Acc:HGNC:9842]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko05210//Colorectal cancer;ko05212//Pancreatic cancer	K08732;K08732;K08732;K08732;K08732;K08732;K08732	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005903//brush border	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000160282	0	0.038	0.052	0.035	0.031	0	0	1	1	1	1	0	FTCD	formimidoyltransferase cyclodeaminase [Source:HGNC Symbol;Acc:HGNC:3974]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00340//Histidine metabolism;ko00670//One carbon pool by folate	K13990;K13990;K13990	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0008017//microtubule binding;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0030409//glutamate formimidoyltransferase activity;GO:0030412//formimidoyltetrahydrofolate cyclodeaminase activity	GO:0006547//histidine metabolic process;GO:0006760//folic acid-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0008152//metabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate;GO:0035999//tetrahydrofolate interconversion;GO:0044237//cellular metabolic process	--
ENSG00000160284	6.3	6.681	7.579	10.253	7.966	6.813	156	167	139	188	165	125	SPATC1L	spermatogenesis and centriole associated 1 like [Source:HGNC Symbol;Acc:HGNC:1298]	-	-	-	-	GO:0005575//cellular_component;GO:0005813//centrosome;GO:0097224//sperm connecting piece	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0042802//identical protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0008154//actin polymerization or depolymerization;GO:0010739//positive regulation of protein kinase A signaling;GO:2000481//positive regulation of cAMP-dependent protein kinase activity	--
ENSG00000160285	53.327	49.987	57.547	59.236	58.328	62.071	4093	4045	3321	3437	3869	3578	LSS	lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K01852;K01852	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane	GO:0000250//lanosterol synthase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0016866//intramolecular transferase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0016104//triterpenoid biosynthetic process;GO:0031647//regulation of protein stability	--
ENSG00000160293	4.946	4.918	5.431	5.684	5.955	6.277	491	486	393	416	497	452	VAV2	vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system;Immune system	ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway	K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730;K05730	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0008361//regulation of cell size;GO:0016477//cell migration;GO:0030031//cell projection assembly;GO:0030032//lamellipodium assembly;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043087//regulation of GTPase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000160294	22.669	22.992	23.764	24.185	23.727	24.481	1944	1910	1564	1468	1702	1486	MCM3AP	minichromosome maintenance complex component 3 associated protein [Source:HGNC Symbol;Acc:HGNC:6946]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0044615//nuclear pore nuclear basket;GO:0070390//transcription export complex 2	GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0010484//H3 histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding	GO:0002376//immune system process;GO:0006406//mRNA export from nucleus;GO:0015031//protein transport;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016573//histone acetylation;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0034728//nucleosome organization;GO:0043966//histone H3 acetylation;GO:0051028//mRNA transport	--
ENSG00000160298	0.541	0.71	0.897	0.812	1.191	0.537	30	36	34	29	52	24	C21orf58	chromosome 21 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:1300]	-	-	-	-	-	-	-	--
ENSG00000160299	3.979	3.455	3.436	3.029	3.336	4.031	750	641	488	350	533	508	PCNT	pericentrin [Source:HGNC Symbol;Acc:HGNC:16068]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0034451//centriolar satellite	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0060090//molecular adaptor activity	GO:0000226//microtubule cytoskeleton organization;GO:0007052//mitotic spindle organization;GO:0007165//signal transduction;GO:0060271//cilium assembly;GO:0090316//positive regulation of intracellular protein transport	--
ENSG00000160305	4.316	4.343	4.946	3.877	4.791	4.334	568	507	479	372	515	439	DIP2A	disco interacting protein 2 homolog A [Source:HGNC Symbol;Acc:HGNC:17217]	-	-	-	-	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0003987//acetate-CoA ligase activity;GO:0005515//protein binding;GO:0016874//ligase activity	GO:0006085//acetyl-CoA biosynthetic process;GO:0007399//nervous system development;GO:0010629//negative regulation of gene expression;GO:0060997//dendritic spine morphogenesis;GO:2000758//positive regulation of peptidyl-lysine acetylation	--
ENSG00000160307	54.291	60.137	54.819	58.855	49.514	52.323	1222	1359	907	980	942	852	S100B	S100 calcium binding protein B [Source:HGNC Symbol;Acc:HGNC:10500]	-	-	-	-	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0048306//calcium-dependent protein binding;GO:0050786//RAGE receptor binding	GO:0007409//axonogenesis;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0007613//memory;GO:0008284//positive regulation of cell population proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048168//regulation of neuronal synaptic plasticity	--
ENSG00000160310	53.503	47.333	54.644	54.349	50.8	57.835	2074	2038	1606	1584	1687	1632	PRMT2	protein arginine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:5186]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0030331//estrogen receptor binding;GO:0033142//progesterone receptor binding;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042803//protein homodimerization activity;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0044877//protein-containing complex binding;GO:0046966//thyroid hormone receptor binding;GO:0050681//androgen receptor binding	"GO:0006479//protein methylation;GO:0007165//signal transduction;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032259//methylation;GO:0034969//histone arginine methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048588//developmental cell growth;GO:0060765//regulation of androgen receptor signaling pathway;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000160318	0.116	0.049	0.313	0.113	0	0	1	1	2	1	0	0	CLDND2	claudin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28511]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000160321	0	0	0	0	0	0	0	0	0	0	0	0	ZNF208	zinc finger protein 208 [Source:HGNC Symbol;Acc:HGNC:12999]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000160323	0.939	0.937	1.079	0.402	0.533	0.755	50	78	40	27	42	51	ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0031012//extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009100//glycoprotein metabolic process;GO:0009636//response to toxic substance;GO:0014075//response to amine;GO:0016485//protein processing;GO:0030168//platelet activation;GO:0030198//extracellular matrix organization;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:0035864//response to potassium ion;GO:0043171//peptide catabolic process;GO:0070670//response to interleukin-4;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071353//cellular response to interleukin-4;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000160325	14.571	16.262	22.335	14.831	14.568	16.316	796	890	626	635	712	685	CACFD1	calcium channel flower domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1365]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0016192//vesicle-mediated transport	--
ENSG00000160326	4.157	4.858	4.911	6.269	4.975	7.269	164	194	144	175	191	211	SLC2A6	solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005353//fructose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0006110//regulation of glycolytic process;GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0015755//fructose transmembrane transport;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:1904659//glucose transmembrane transport	--
ENSG00000160336	4.013	3.58	3.405	2.748	3.113	3.337	269	209	138.12	131	163	150	ZNF761	zinc finger protein 761 [Source:HGNC Symbol;Acc:HGNC:23179]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000160339	0	0	0	0	0	0	0	0	0	0	0	0	FCN2	ficolin 2 [Source:HGNC Symbol;Acc:HGNC:3624]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1905370//serine-type endopeptidase complex	GO:0003823//antigen binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043394//proteoglycan binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0097367//carbohydrate derivative binding;GO:2001065//mannan binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0008228//opsonization;GO:0043654//recognition of apoptotic cell;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:1903028//positive regulation of opsonization"	--
ENSG00000160345	9.522	8.023	8.089	7.916	4.903	4.857	158	129	99	101	67	63	C9orf116	chromosome 9 open reading frame 116 [Source:HGNC Symbol;Acc:HGNC:28435]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0007368//determination of left/right symmetry;GO:0010468//regulation of gene expression;GO:0071494//cellular response to UV-C	--
ENSG00000160349	0.124	0	0	0	0	0	2	0	0	0	0	0	LCN1	lipocalin 1 [Source:HGNC Symbol;Acc:HGNC:6525]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031404//chloride ion binding;GO:0036094//small molecule binding	GO:0001895//retina homeostasis;GO:0006508//proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000160352	3.514	2.284	2.868	1.895	2.062	2.391	273	179	132	116	135	124	ZNF714	zinc finger protein 714 [Source:HGNC Symbol;Acc:HGNC:27124]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000160360	34.525	34.284	35.753	41.539	41.814	38.544	2387	2421	1871	2176	2488	2022	GPSM1	G protein signaling modulator 1 [Source:HGNC Symbol;Acc:HGNC:17858]	Human Diseases	Substance dependence	ko05030//Cocaine addiction	K15839	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0007399//nervous system development;GO:0016239//positive regulation of macroautophagy;GO:0030154//cell differentiation;GO:0034260//negative regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:1905098//negative regulation of guanyl-nucleotide exchange factor activity	--
ENSG00000160392	5.941	6.794	5.229	6.991	5.952	5.421	236	244	164	188	232	177	C19orf47	chromosome 19 open reading frame 47 [Source:HGNC Symbol;Acc:HGNC:26723]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000160396	0	0.039	0.053	0.16	0.047	0.054	0	2	2	6	2	2	HIPK4	homeodomain interacting protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:19007]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K08826	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0046777//protein autophosphorylation;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000160401	0.094	0.205	0.054	0	0.197	0.061	7.24	13.56	3.07	0	9.01	3.41	CFAP157	cilia and flagella associated protein 157 [Source:HGNC Symbol;Acc:HGNC:27843]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0008017//microtubule binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation	--
ENSG00000160404	3.136	2.941	2.803	4.238	3.1	3.226	98	89	64	87	86	80	TOR2A	torsin family 2 member A [Source:HGNC Symbol;Acc:HGNC:11996]	-	-	-	-	GO:0005576//extracellular region;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0000166//nucleotide binding;GO:0005179//hormone activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000160408	12.358	12.866	15.202	13.193	16.273	15.121	613.65	641.79	559.74	488.56	686.45	548.9	ST6GALNAC6	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:23364]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03376;K03376	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006677//glycosylceramide metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0009100//glycoprotein metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0009988//cell-cell recognition;GO:0097503//sialylation	--
ENSG00000160410	16.123	17.192	18.057	18.403	20.842	20.898	722	783	603	596	742	664	SHKBP1	SH3KBP1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19214]	-	-	-	-	GO:0005764//lysosome	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000160439	6.103	6.939	7.881	6.861	7.196	7.419	224	256	214	183	217	199	RDH13	retinol dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:19978]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11161;K11161	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0016491//oxidoreductase activity;GO:0052650//NADP-retinol dehydrogenase activity	GO:0006629//lipid metabolic process;GO:0009644//response to high light intensity;GO:0010842//retina layer formation;GO:0042462//eye photoreceptor cell development;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process	--
ENSG00000160445	28.21	26.644	29.477	27.765	28.781	26.131	2022	2059	1588	1664	1796	1470	ZER1	zyg-11 related cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:30960]	-	-	-	-	GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0030162//regulation of proteolysis;GO:0031331//positive regulation of cellular catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000160446	13.883	15.737	13.842	19.537	17.627	15.38	330	376	243	344	354	266	ZDHHC12	zinc finger DHHC-type palmitoyltransferase 12 [Source:HGNC Symbol;Acc:HGNC:19159]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	"GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0097116//gephyrin clustering involved in postsynaptic density assembly"	--
ENSG00000160447	4.902	4.255	4.887	2.992	4.171	4.648	345	301	254	156	248	238	PKN3	protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K23692	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0010631//epithelial cell migration;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000160460	1.044	1.094	0.769	1.292	1.441	1.258	170	168	89	161	170	128	SPTBN4	"spectrin beta, non-erythrocytic 4 [Source:HGNC Symbol;Acc:HGNC:14896]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:0030054//cell junction;GO:0030424//axon;GO:0030864//cortical actin cytoskeleton;GO:0033268//node of Ranvier;GO:0033270//paranode region of axon;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043203//axon hillock;GO:0070062//extracellular exosome;GO:0070852//cell body fiber;GO:0071944//cell periphery	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019902//phosphatase binding;GO:0030506//ankyrin binding;GO:0030507//spectrin binding;GO:0051015//actin filament binding;GO:0106006//cytoskeletal protein-membrane anchor activity	GO:0002028//regulation of sodium ion transport;GO:0007010//cytoskeleton organization;GO:0007409//axonogenesis;GO:0007605//sensory perception of sound;GO:0007628//adult walking behavior;GO:0008104//protein localization;GO:0009566//fertilization;GO:0010459//negative regulation of heart rate;GO:0016192//vesicle-mediated transport;GO:0019226//transmission of nerve impulse;GO:0021952//central nervous system projection neuron axonogenesis;GO:0022414//reproductive process;GO:0030036//actin cytoskeleton organization;GO:0030534//adult behavior;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0034613//cellular protein localization;GO:0040018//positive regulation of multicellular organism growth;GO:0045162//clustering of voltage-gated sodium channels;GO:0051693//actin filament capping;GO:0061337//cardiac conduction;GO:0072659//protein localization to plasma membrane	--
ENSG00000160469	2.78	2.908	3.065	2.653	3.718	2.82	150	159	130	97	130	110	BRSK1	BR serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18994]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0150034//distal axon	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0043015//gamma-tubulin binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007269//neurotransmitter secretion;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0008306//associative learning;GO:0009411//response to UV;GO:0010975//regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030010//establishment of cell polarity;GO:0030182//neuron differentiation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0048167//regulation of synaptic plasticity;GO:0048812//neuron projection morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051298//centrosome duplication;GO:0090176//microtubule cytoskeleton organization involved in establishment of planar polarity;GO:0099504//synaptic vesicle cycle;GO:2000807//regulation of synaptic vesicle clustering	--
ENSG00000160471	0.406	0.519	0.476	0.208	0.506	0.855	17	19	14	5	13	19	COX6B2	cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267;K02267	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0030061//mitochondrial crista;GO:0045277//respiratory chain complex IV	GO:0005515//protein binding	GO:0006119//oxidative phosphorylation	--
ENSG00000160472	0	0	0	0.215	0	0	0	0	0	2	0	0	TMEM190	transmembrane protein 190 [Source:HGNC Symbol;Acc:HGNC:29632]	-	-	-	-	GO:0002079//inner acrosomal membrane;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0043621//protein self-association	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000160505	0	0	0	0	0	0	0	0	0	0	0	0	NLRP4	NLR family pyrin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:22943]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K22265	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0006954//inflammatory response	--
ENSG00000160539	0	0.061	0	0.095	0.083	0.257	0	2	0	3	3	8	PLPP7	phospholipid phosphatase 7 (inactive) [Source:HGNC Symbol;Acc:HGNC:28174]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0042392//sphingosine-1-phosphate phosphatase activity	GO:0010832//negative regulation of myotube differentiation;GO:0016311//dephosphorylation	--
ENSG00000160551	9.709	7.292	6.697	4.664	5.439	5.534	2546	1922	1297	906	1205	1056	TAOK1	TAO kinase 1 [Source:HGNC Symbol;Acc:HGNC:29259]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04429	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043014//alpha-tubulin binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0048156//tau protein binding;GO:0048487//beta-tubulin binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0000226//microtubule cytoskeleton organization;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007026//negative regulation of microtubule depolymerization;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0016310//phosphorylation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0032956//regulation of actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0043408//regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation;GO:0048812//neuron projection morphogenesis;GO:0051493//regulation of cytoskeleton organization;GO:0070050//neuron cellular homeostasis;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097194//execution phase of apoptosis;GO:1901985//positive regulation of protein acetylation	--
ENSG00000160563	5.117	7.29	6.014	8.036	8.076	6.889	147	210	127	171	196	144	MED27	mediator complex subunit 27 [Source:HGNC Symbol;Acc:HGNC:2377]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15170	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0016567//protein ubiquitination;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000160570	13.482	15.876	13.96	15.717	19.792	17.679	523	623	397	455	630	481	DEDD2	death effector domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24450]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity	"GO:0006396//RNA processing;GO:0006915//apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0016075//rRNA catabolic process;GO:0019725//cellular homeostasis;GO:0030262//apoptotic nuclear changes;GO:0035556//intracellular signal transduction;GO:0042981//regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000160584	6.298	7.18	7.028	5.945	6.202	6.271	755	814	600	504	609	526	SIK3	SIK family kinase 3 [Source:HGNC Symbol;Acc:HGNC:29165]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:1904263//positive regulation of TORC1 signaling;GO:1904515//positive regulation of TORC2 signaling	--
ENSG00000160588	1.016	1.058	0.967	0.879	0.817	1.514	63	60	59	46	57	52	MPZL3	myelin protein zero like 3 [Source:HGNC Symbol;Acc:HGNC:27279]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0042633//hair cycle	--
ENSG00000160593	1.013	1.283	0.551	0.936	0.826	1.274	32	44	13	23	21	31	JAML	junction adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:19084]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030593//neutrophil chemotaxis;GO:0035696//monocyte extravasation;GO:0046629//gamma-delta T cell activation;GO:0050900//leukocyte migration;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0072672//neutrophil extravasation	--
ENSG00000160602	0.486	0.83	2.5	0.638	1.056	0.946	36	59	46	35	41	51	NEK8	NIMA related kinase 8 [Source:HGNC Symbol;Acc:HGNC:13387]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection;GO:0097543//ciliary inversin compartment;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007059//chromosome segregation;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0009887//animal organ morphogenesis;GO:0016310//phosphorylation;GO:0035330//regulation of hippo signaling	--
ENSG00000160606	1.851	2.177	2.223	2.503	1.361	2.434	40	42	32	34	24	34	TLCD1	TLC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25177]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007009//plasma membrane organization;GO:0055088//lipid homeostasis;GO:0055091//phospholipid homeostasis;GO:0071709//membrane assembly;GO:0097035//regulation of membrane lipid distribution	--
ENSG00000160613	5.315	5.658	6.151	5.178	5.896	5.974	421.11	449.75	356.04	299.99	375.06	290.05	PCSK7	proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016485//protein processing;GO:0016486//peptide hormone processing	--
ENSG00000160633	31.813	31.689	34.338	30.123	31.662	31.632	2002.52	2003.42	1590.87	1402.26	1678.26	1446.03	SAFB	scaffold attachment factor B [Source:HGNC Symbol;Acc:HGNC:10520]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030496//midbody	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0050684//regulation of mRNA processing"	--
ENSG00000160654	0	0	0	0	0	0	0	0	0	0	0	0	CD3G	CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Immune system;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview	ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04640//Hematopoietic cell lineage;ko05162//Measles;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06452;K06452;K06452;K06452;K06452;K06452;K06452;K06452;K06452;K06452	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042105//alpha-beta T cell receptor complex;GO:0042106//gamma-delta T cell receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0042608//T cell receptor binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007163//establishment or maintenance of cell polarity;GO:0007166//cell surface receptor signaling pathway;GO:0015031//protein transport;GO:0042110//T cell activation;GO:0045059//positive thymic T cell selection;GO:0046629//gamma-delta T cell activation;GO:0046631//alpha-beta T cell activation;GO:0050852//T cell receptor signaling pathway;GO:0065003//protein-containing complex assembly;GO:0070228//regulation of lymphocyte apoptotic process	--
ENSG00000160678	29.619	28.863	24.168	15.044	14.716	16.22	352	341	219	134	153	141	S100A1	S100 calcium binding protein A1 [Source:HGNC Symbol;Acc:HGNC:10486]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0032991//protein-containing complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0051117//ATPase binding	GO:0008016//regulation of heart contraction;GO:0021762//substantia nigra development;GO:0035556//intracellular signal transduction;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000160679	19.815	21.035	18.906	18.911	18.794	19.662	853	892	588	593	665	613	CHTOP	chromatin target of PRMT1 [Source:HGNC Symbol;Acc:HGNC:24511]	-	-	-	-	GO:0000346//transcription export complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding	GO:0001701//in utero embryonic development;GO:0006406//mRNA export from nucleus;GO:0008284//positive regulation of cell population proliferation;GO:0031062//positive regulation of histone methylation;GO:0032781//positive regulation of ATPase activity;GO:0051028//mRNA transport;GO:0051096//positive regulation of helicase activity	--
ENSG00000160683	0	0	0	0	0	0	0	0	0	0	0	0	CXCR5	C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04190;K04190;K04190	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0030595//leukocyte chemotaxis;GO:0032467//positive regulation of cytokinesis;GO:0042113//B cell activation;GO:0048535//lymph node development;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000160685	10.763	10.555	12.624	12.479	13.962	13.759	798	763	667	694	864	710	ZBTB7B	zinc finger and BTB domain containing 7B [Source:HGNC Symbol;Acc:HGNC:18668]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001865//NK T cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007398//ectoderm development;GO:0007595//lactation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0031065//positive regulation of histone deacetylation;GO:0032740//positive regulation of interleukin-17 production;GO:0032868//response to insulin;GO:0043370//regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043376//regulation of CD8-positive, alpha-beta T cell differentiation;GO:0043377//negative regulation of CD8-positive, alpha-beta T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0051141//negative regulation of NK T cell proliferation;GO:0090336//positive regulation of brown fat cell differentiation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1990845//adaptive thermogenesis;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000640//positive regulation of SREBP signaling pathway"	ZBTB
ENSG00000160688	10.025	12.392	11.649	10.967	12.462	13.412	364	452	311	292	381	354	FLAD1	flavin adenine dinucleotide synthetase 1 [Source:HGNC Symbol;Acc:HGNC:24671]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00740//Riboflavin metabolism	K00953;K00953	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003919//FMN adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042802//identical protein binding	GO:0006747//FAD biosynthetic process;GO:0006771//riboflavin metabolic process	--
ENSG00000160691	36.751	33.568	32.106	49.142	40.886	40.081	1935	2027	1471	1797	1985	1625	SHC1	SHC adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:10840]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune system;Substance dependence;Immune system;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Drug resistance: antineoplastic;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system	"ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko01522//Endocrine resistance;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway"	K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279;K06279	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070435//Shc-EGFR complex	GO:0001784//phosphotyrosine residue binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0046875//ephrin receptor binding;GO:0048408//epidermal growth factor binding	"GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042127//regulation of cell population proliferation;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0090322//regulation of superoxide metabolic process;GO:0098609//cell-cell adhesion"	--
ENSG00000160695	17.152	19.624	19.456	22.981	20.437	21.545	1120	1304	952	1127	1141	1041	VPS11	VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20179	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005776//autophagosome;GO:0005884//actin filament;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030897//HOPS complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0033263//CORVET complex;GO:0048786//presynaptic active zone;GO:0099023//vesicle tethering complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0046907//intracellular transport;GO:1901998//toxin transport	--
ENSG00000160703	8.293	8.772	9.385	9.789	9.819	9.892	632	681	509	572	649	550	NLRX1	NLR family member X1 [Source:HGNC Symbol;Acc:HGNC:29890]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Infectious disease: viral;Immune system	ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04622//RIG-I-like receptor signaling pathway	K12653;K12653;K12653	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0002376//immune system process;GO:0032688//negative regulation of interferon-beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0035556//intracellular signal transduction;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045824//negative regulation of innate immune response;GO:0050728//negative regulation of inflammatory response	--
ENSG00000160710	51.725	56.556	56.355	51.338	56.158	53.643	5806	6195	4598	4223	5220	4398	ADAR	adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system	ko05171//Coronavirus disease - COVID-19;ko05164//Influenza A;ko05162//Measles;ko04623//Cytosolic DNA-sensing pathway	K12968;K12968;K12968;K12968	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0044530//supraspliceosomal complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0004000//adenosine deaminase activity;GO:0005515//protein binding;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001649//osteoblast differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002376//immune system process;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0006382//adenosine to inosine editing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0009615//response to virus;GO:0016553//base conversion or substitution editing;GO:0030218//erythrocyte differentiation;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0035455//response to interferon-alpha;GO:0043066//negative regulation of apoptotic process;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045070//positive regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060216//definitive hemopoiesis;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061484//hematopoietic stem cell homeostasis;GO:0098586//cellular response to virus;GO:1900369//negative regulation of RNA interference	--
ENSG00000160712	0.135	0.075	0.098	0.308	0.124	0.218	5	5	4	20	11	19	IL6R	interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Immune system;Signal transduction;Endocrine and metabolic disease;Signal transduction;Immune system;Signaling molecules and interaction;Drug resistance: antineoplastic	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04066//HIF-1 signaling pathway;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko01521//EGFR tyrosine kinase inhibitor resistance	K05055;K05055;K05055;K05055;K05055;K05055;K05055;K05055;K05055;K05055;K05055;K05055	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005896//interleukin-6 receptor complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043235//receptor complex;GO:0070110//ciliary neurotrophic factor receptor complex	GO:0004896//cytokine receptor activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0004915//interleukin-6 receptor activity;GO:0004921//interleukin-11 receptor activity;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019955//cytokine binding;GO:0019970//interleukin-11 binding;GO:0019981//interleukin-6 binding;GO:0042803//protein homodimerization activity;GO:0070119//ciliary neurotrophic factor binding	GO:0002384//hepatic immune response;GO:0002446//neutrophil mediated immunity;GO:0002548//monocyte chemotaxis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006953//acute-phase response;GO:0008284//positive regulation of cell population proliferation;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0010573//vascular endothelial growth factor production;GO:0019221//cytokine-mediated signaling pathway;GO:0031018//endocrine pancreas development;GO:0032717//negative regulation of interleukin-8 production;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0032966//negative regulation of collagen biosynthetic process;GO:0034097//response to cytokine;GO:0038154//interleukin-11-mediated signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043410//positive regulation of MAPK cascade;GO:0045669//positive regulation of osteoblast differentiation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050896//response to stimulus;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0072540//T-helper 17 cell lineage commitment;GO:0097191//extrinsic apoptotic signaling pathway	--
ENSG00000160714	18.144	18.007	17.231	17.1	17.283	21.132	1219	1216	855	851	981	1033	UBE2Q1	ubiquitin conjugating enzyme E2 Q1 [Source:HGNC Symbol;Acc:HGNC:15698]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10582	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030175//filopodium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0001967//suckling behavior;GO:0007566//embryo implantation;GO:0007617//mating behavior;GO:0009566//fertilization;GO:0016567//protein ubiquitination;GO:0061458//reproductive system development;GO:0070459//prolactin secretion	--
ENSG00000160716	0	0.041	0.029	0.027	0.01	0	0	5	2	1	1	0	CHRNB2	cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Cancer: overview;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse;ko05033//Nicotine addiction	K04813;K04813;K04813;K04813	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0044853//plasma membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098981//cholinergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:0044877//protein-containing complex binding;GO:0050997//quaternary ammonium group binding;GO:1901363//heterocyclic compound binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001666//response to hypoxia;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0007612//learning;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0008542//visual learning;GO:0014059//regulation of dopamine secretion;GO:0019233//sensory perception of pain;GO:0021562//vestibulocochlear nerve development;GO:0021631//optic nerve morphogenesis;GO:0021771//lateral geniculate nucleus development;GO:0021952//central nervous system projection neuron axonogenesis;GO:0030890//positive regulation of B cell proliferation;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0033603//positive regulation of dopamine secretion;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0035095//behavioral response to nicotine;GO:0035176//social behavior;GO:0042053//regulation of dopamine metabolic process;GO:0042113//B cell activation;GO:0042220//response to cocaine;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0042391//regulation of membrane potential;GO:0045471//response to ethanol;GO:0045759//negative regulation of action potential;GO:0048814//regulation of dendrite morphogenesis;GO:0050877//nervous system process;GO:0050890//cognition;GO:0051899//membrane depolarization;GO:0051963//regulation of synapse assembly;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0060084//synaptic transmission involved in micturition;GO:0095500//acetylcholine receptor signaling pathway;GO:1905144//response to acetylcholine"	--
ENSG00000160741	7.64	8.472	9.411	9.91	10.897	12.045	415	461	374	398	495	472	CRTC2	CREB regulated transcription coactivator 2 [Source:HGNC Symbol;Acc:HGNC:27301]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Signal transduction;Endocrine and metabolic disease;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway	K16333;K16333;K16333;K16333;K16333	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding	GO:0006094//gluconeogenesis;GO:0032793//positive regulation of CREB transcription factor activity;GO:0042593//glucose homeostasis;GO:0043970//histone H3-K9 acetylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051289//protein homotetramerization;GO:1901998//toxin transport	--
ENSG00000160746	21.292	25.633	27.663	27.049	24.493	24.228	1005	1004	767	939	968	845	ANO10	anoctamin 10 [Source:HGNC Symbol;Acc:HGNC:25519]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005227//calcium activated cation channel activity;GO:0005229//intracellular calcium activated chloride channel activity	GO:0006812//cation transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000160752	54.657	52.717	58.269	67.056	58.039	66.672	1376	1336	1074	1252	1239	1238	FDPS	farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631]	Metabolism;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Infectious disease: viral;Infectious disease: viral;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko05166//Human T-cell leukemia virus 1 infection;ko05164//Influenza A;ko00900//Terpenoid backbone biosynthesis	K00787;K00787;K00787;K00787	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0004161//dimethylallyltranstransferase activity;GO:0004337//geranyltranstransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0033384//geranyl diphosphate biosynthetic process;GO:0045337//farnesyl diphosphate biosynthetic process	--
ENSG00000160753	7.093	7.867	8.903	6.539	10.255	9.229	296	334	285	207	368	278	RUSC1	RUN and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17153]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0014069//postsynaptic density;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding	GO:0000209//protein polyubiquitination	--
ENSG00000160767	10.387	11.524	14.172	14.666	14.792	15.535	617	657	578	612	739	636	FAM189B	family with sequence similarity 189 member B [Source:HGNC Symbol;Acc:HGNC:1233]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0008150//biological_process	--
ENSG00000160781	0.655	0.703	0.569	0.586	0.856	0.639	28	27	11	13	19	19	PAQR6	progestin and adipoQ receptor family member 6 [Source:HGNC Symbol;Acc:HGNC:30132]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038023//signaling receptor activity	-	--
ENSG00000160783	34.283	34.744	38.793	39.405	36.906	45.643	755.89	765.86	627.86	639.68	685.15	728.37	PMF1	polyamine modulated factor 1 [Source:HGNC Symbol;Acc:HGNC:9112]	-	-	-	-	"GO:0000444//MIS12/MIND type complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000818//nuclear MIS12/MIND complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031617//NMS complex;GO:0043231//intracellular membrane-bounded organelle"	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043522//leucine zipper domain binding	"GO:0006366//transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division"	--
ENSG00000160785	13.793	13.031	14.078	13.963	15.288	15.919	1002	950	754	748	938	838	SLC25A44	solute carrier family 25 member 44 [Source:HGNC Symbol;Acc:HGNC:29036]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0015658//branched-chain amino acid transmembrane transporter activity	GO:0006865//amino acid transport;GO:0009083//branched-chain amino acid catabolic process;GO:0015803//branched-chain amino acid transport;GO:0055085//transmembrane transport;GO:0120161//regulation of cold-induced thermogenesis	--
ENSG00000160789	98.983	99.904	115.662	125.591	111.021	130.483	4630	4719	3963	4309	4386	4427	LMNA	lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Cardiovascular disease;Cell growth and death;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko04210//Apoptosis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12641;K12641;K12641;K12641	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005638//lamin filament;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0035861//site of double-strand break;GO:0048471//perinuclear region of cytoplasm	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006606//protein import into nucleus;GO:0006997//nucleus organization;GO:0006998//nuclear envelope organization;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0030334//regulation of cell migration;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0031647//regulation of protein stability;GO:0032204//regulation of telomere maintenance;GO:0034504//protein localization to nucleus;GO:0034613//cellular protein localization;GO:0055015//ventricular cardiac muscle cell development;GO:0071456//cellular response to hypoxia;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0090343//positive regulation of cell aging;GO:1900114//positive regulation of histone H3-K9 trimethylation;GO:1900180//regulation of protein localization to nucleus;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:1990683//DNA double-strand break attachment to nuclear envelope;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000160791	0	0	0	0	0	0	0	0	0	0	0	0	CCR5	C-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1606]	Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: parasitic;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05145//Toxoplasmosis;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04180;K04180;K04180;K04180;K04180;K04180;K04180;K04180;K04180	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0003779//actin binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0042802//identical protein binding;GO:0071791//chemokine (C-C motif) ligand 5 binding	GO:0000165//MAPK cascade;GO:0002407//dendritic cell chemotaxis;GO:0006816//calcium ion transport;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0019722//calcium-mediated signaling;GO:0023052//signaling;GO:0046718//viral entry into host cell;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070723//response to cholesterol;GO:0071222//cellular response to lipopolysaccharide;GO:2000110//negative regulation of macrophage apoptotic process	--
ENSG00000160796	1.425	1.136	1.895	2.028	3.121	1.38	206	204	194	145	257	163	NBEAL2	neurobeachin like 2 [Source:HGNC Symbol;Acc:HGNC:31928]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043226//organelle;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0008104//protein localization;GO:0030220//platelet formation	--
ENSG00000160799	10.638	12.01	11.71	12.039	9.895	11.543	193	212	139	160	146	149	CCDC12	coiled-coil domain containing 12 [Source:HGNC Symbol;Acc:HGNC:28332]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12871	GO:0005684//U2-type spliceosomal complex;GO:0071014//post-mRNA release spliceosomal complex	GO:0005515//protein binding	-	--
ENSG00000160801	0.149	0.271	0.171	0.234	0.579	0.204	6	9	5	7	18	6	PTH1R	parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Endocrine system;Excretory system	"ko04080//Neuroactive ligand-receptor interaction;ko04928//Parathyroid hormone synthesis, secretion and action;ko04961//Endocrine and other factor-regulated calcium reabsorption"	K04585;K04585;K04585	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004991//parathyroid hormone receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association	"GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001701//in utero embryonic development;GO:0002062//chondrocyte differentiation;GO:0002076//osteoblast development;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0030282//bone mineralization;GO:0045453//bone resorption;GO:0048469//cell maturation;GO:0060732//positive regulation of inositol phosphate biosynthetic process"	--
ENSG00000160803	14.765	15.761	15.235	18.443	18.337	17.425	1097	1177	836	1015	1151	942	UBQLN4	ubiquilin 4 [Source:HGNC Symbol;Acc:HGNC:1237]	Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Folding, sorting and degradation"	ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum	K04523;K04523	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0031595//nuclear proteasome complex;GO:0031597//cytosolic proteasome complex;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0090734//site of DNA damage	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding	GO:0006281//DNA repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0006974//cellular response to DNA damage stimulus;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:1901097//negative regulation of autophagosome maturation;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000160808	0.136	0.108	0.18	0.677	0	0.729	5	2	4	5	0	9	MYL3	myosin light chain 3 [Source:HGNC Symbol;Acc:HGNC:7584]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Cardiovascular disease;Circulatory system;Signal transduction;Cardiovascular disease;Circulatory system	ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K12749;K12749;K12749;K12749;K12749	GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030017//sarcomere;GO:0031672//A band;GO:0031674//I band	GO:0003785//actin monomer binding;GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle;GO:0032038//myosin II heavy chain binding	GO:0002026//regulation of the force of heart contraction;GO:0006942//regulation of striated muscle contraction;GO:0032781//positive regulation of ATPase activity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060048//cardiac muscle contraction	--
ENSG00000160813	5.056	5.529	5.965	5.677	5.392	6.881	101	111	88	84	91	100	PPP1R35	protein phosphatase 1 regulatory subunit 35 [Source:HGNC Symbol;Acc:HGNC:28320]	-	-	-	-	GO:0005813//centrosome;GO:0005814//centriole	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019902//phosphatase binding	GO:0010923//negative regulation of phosphatase activity;GO:0045724//positive regulation of cilium assembly;GO:0048570//notochord morphogenesis;GO:1903724//positive regulation of centriole elongation	--
ENSG00000160818	5.824	4.852	5.736	3.495	4.29	2.984	203	191	154	88	132	97	GPATCH4	G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]	-	-	-	-	-	GO:0003676//nucleic acid binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000160838	0.122	0	0.099	0	0.029	0	5	0	3	0	1	0	LRRC71	leucine rich repeat containing 71 [Source:HGNC Symbol;Acc:HGNC:26556]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000160856	0	0	0	0	0	0.014	0	0	0	0	0	1	FCRL3	Fc receptor like 3 [Source:HGNC Symbol;Acc:HGNC:18506]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019902//phosphatase binding;GO:0019903//protein phosphatase binding;GO:1990782//protein tyrosine kinase binding	GO:0002638//negative regulation of immunoglobulin production;GO:0007166//cell surface receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0034163//regulation of toll-like receptor 9 signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0045577//regulation of B cell differentiation;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0050864//regulation of B cell activation;GO:0090279//regulation of calcium ion import;GO:1905184//positive regulation of protein serine/threonine phosphatase activity	--
ENSG00000160862	0.612	0.69	0.608	0.793	1.276	0.729	15	17	11	15	27	13	AZGP1	"alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:910]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001895//retina homeostasis;GO:0002476//antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0071806//protein transmembrane transport;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000160867	0.387	0.255	0.453	0.408	0.34	0.789	23	15	17	8	13	17	FGFR4	fibroblast growth factor receptor 4 [Source:HGNC Symbol;Acc:HGNC:3691]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Cellular Processes	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Transport and catabolism;Signal transduction;Cell motility;Signal transduction;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells	K05095;K05095;K05095;K05095;K05095;K05095;K05095;K05095;K05095	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017134//fibroblast growth factor binding	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010715//regulation of extracellular matrix disassembly;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019216//regulation of lipid metabolic process;GO:0033674//positive regulation of kinase activity;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0043085//positive regulation of catalytic activity;GO:0045862//positive regulation of proteolysis;GO:0046777//protein autophosphorylation;GO:0055062//phosphate ion homeostasis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070857//regulation of bile acid biosynthetic process;GO:0071495//cellular response to endogenous stimulus;GO:2000573//positive regulation of DNA biosynthetic process	--
ENSG00000160868	0	0	0	0	0	0	0	0	0	0	0	0	CYP3A4	cytochrome P450 family 3 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:2637]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00591//Linoleic acid metabolism	K17689;K17689;K17689;K17689;K17689;K17689;K17689;K17689;K17689;K17689	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005496//steroid binding;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0034875//caffeine oxidase activity;GO:0046872//metal ion binding;GO:0050591//quinine 3-monooxygenase activity;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0062181//1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity;GO:0062187//anandamide 8,9 epoxidase activity;GO:0062188//anandamide 11,12 epoxidase activity;GO:0062189//anandamide 14,15 epoxidase activity;GO:0070330//aromatase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0101021//estrogen 2-hydroxylase activity;GO:0102320//1,8-cineole 2-exo-monooxygenase activity"	GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006706//steroid catabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0009822//alkaloid catabolic process;GO:0016098//monoterpenoid metabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0042178//xenobiotic catabolic process;GO:0042359//vitamin D metabolic process;GO:0042369//vitamin D catabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0046222//aflatoxin metabolic process;GO:0046483//heterocycle metabolic process;GO:0070989//oxidative demethylation	--
ENSG00000160870	0	0	0	0	0	0	0	0	0	0	0	0	CYP3A7	cytochrome P450 family 3 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:2640]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Metabolism of cofactors and vitamins;Lipid metabolism	ko01100//Metabolic pathways;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00140//Steroid hormone biosynthesis	K17691;K17691;K17691;K17691	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0062183//all-trans retinoic acid 18-hydroxylase activity;GO:0070330//aromatase activity;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0101021//estrogen 2-hydroxylase activity"	GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0070989//oxidative demethylation	--
ENSG00000160877	28.141	29.787	24.673	33.318	35.144	34.815	1521	1513	1136	1343	1489	1120	NACC1	nucleus accumbens associated 1 [Source:HGNC Symbol;Acc:HGNC:20967]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000160882	0	0	0	0	0	0	0	0	0	0	0	0	CYP11B1	cytochrome P450 family 11 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2591]	Metabolism;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis	K00497;K00497;K00497;K00497	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	"GO:0004497//monooxygenase activity;GO:0004507//steroid 11-beta-monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0047783//corticosterone 18-monooxygenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006955//immune response;GO:0008203//cholesterol metabolic process;GO:0008217//regulation of blood pressure;GO:0016125//sterol metabolic process;GO:0032342//aldosterone biosynthetic process;GO:0032870//cellular response to hormone stimulus;GO:0034650//cortisol metabolic process;GO:0034651//cortisol biosynthetic process;GO:0035865//cellular response to potassium ion;GO:0042593//glucose homeostasis;GO:0071375//cellular response to peptide hormone stimulus	--
ENSG00000160883	0	0	0	0	0.037	0	0	0	0	0	2	0	HK3	hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Infectious disease: bacterial;Endocrine system;Signal transduction;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Endocrine and metabolic disease;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Biosynthesis of other secondary metabolites	"ko01100//Metabolic pathways;ko05131//Shigellosis;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00524//Neomycin, kanamycin and gentamicin biosynthesis"	K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844;K00844	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004340//glucokinase activity;GO:0004396//hexokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0008865//fructokinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019158//mannokinase activity"	GO:0001678//cellular glucose homeostasis;GO:0005975//carbohydrate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006096//glycolytic process;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0051156//glucose 6-phosphate metabolic process;GO:0061621//canonical glycolysis	--
ENSG00000160886	0.018	0.071	0.073	0.073	0	0.074	1	4	3	3	0	3	LY6K	lymphocyte antigen 6 family member K [Source:HGNC Symbol;Acc:HGNC:24225]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft	-	GO:0007339//binding of sperm to zona pellucida	--
ENSG00000160888	12.143	13.258	12.236	10.664	10.742	11.303	510	566	389	351	417	355	IER2	immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048870//cell motility;GO:0071774//response to fibroblast growth factor	--
ENSG00000160908	5.234	4.878	5.838	5.269	4.644	4.092	233	221	193	173	173	133	ZNF394	zinc finger protein 394 [Source:HGNC Symbol;Acc:HGNC:18832]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000160917	7.623	5.926	6.534	7.044	7.989	7.193	263	218	179	192	226	189	CPSF4	cleavage and polyadenylation specific factor 4 [Source:HGNC Symbol;Acc:HGNC:2327]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05164//Influenza A;ko03015//mRNA surveillance pathway	K14404;K14404	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006397//mRNA processing;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000160932	19.885	20.036	19.165	21.051	23.086	21.538	454	470	323	361	447	371	LY6E	lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0030550//acetylcholine receptor inhibitor activity;GO:0033130//acetylcholine receptor binding	GO:0001701//in utero embryonic development;GO:0007166//cell surface receptor signaling pathway;GO:0030325//adrenal gland development;GO:0035265//organ growth;GO:0042415//norepinephrine metabolic process;GO:0046597//negative regulation of viral entry into host cell;GO:0048242//epinephrine secretion;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0095500//acetylcholine receptor signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000160948	55.124	57.002	66.265	78.156	64.475	60.238	875	994	814	941	895	723	VPS28	VPS28 subunit of ESCRT-I [Source:HGNC Symbol;Acc:HGNC:18178]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12184	GO:0000813//ESCRT I complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043657//host cell;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding	GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0031397//negative regulation of protein ubiquitination;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045732//positive regulation of protein catabolic process;GO:0046907//intracellular transport;GO:0075733//intracellular transport of virus;GO:2000397//positive regulation of ubiquitin-dependent endocytosis	--
ENSG00000160949	1.266	1.641	1.801	1.465	1.864	1.565	119	155	125	102	148	107	TONSL	"tonsoku like, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:7801]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0035101//FACT complex;GO:0042555//MCM complex;GO:0043596//nuclear replication fork	GO:0005515//protein binding;GO:0042393//histone binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing	--
ENSG00000160951	0.648	0.611	0.832	0.599	0.767	0.75	19	18	18	13	19	16	PTGER1	prostaglandin E receptor 1 [Source:HGNC Symbol;Acc:HGNC:9593]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Infectious disease: viral	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05163//Human cytomegalovirus infection	K04258;K04258;K04258;K04258	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004955//prostaglandin receptor activity;GO:0004957//prostaglandin E receptor activity;GO:0031748//D1 dopamine receptor binding	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032496//response to lipopolysaccharide	--
ENSG00000160953	16.143	18.167	18.053	17.285	19.383	13.784	1234	1334	967	869	1137	777	PWWP3A	"PWWP domain containing 3A, DNA repair factor [Source:HGNC Symbol;Acc:HGNC:29641]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031491//nucleosome binding	GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000160957	1.516	1.818	1.735	1.744	0.508	1.411	71	89	61	67	34	53	RECQL4	RecQ like helicase 4 [Source:HGNC Symbol;Acc:HGNC:9949]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016020//membrane"	GO:0000166//nucleotide binding;GO:0000405//bubble DNA binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0032357//oxidized purine DNA binding;GO:0043138//3'-5' DNA helicase activity;GO:0061821//telomeric D-loop binding;GO:1990814//DNA/DNA annealing activity	GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0032508//DNA duplex unwinding;GO:0061820//telomeric D-loop disassembly	--
ENSG00000160959	5.176	4.829	6.716	7.607	6.595	6.335	433.77	411.82	380.04	477.64	467.53	430.8	LRRC14	leucine rich repeat containing 14 [Source:HGNC Symbol;Acc:HGNC:20419]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0019900//kinase binding	GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034122//negative regulation of toll-like receptor signaling pathway	--
ENSG00000160961	2.408	2.45	2.364	2.462	2.13	2.036	224	223	167	160	173	142	ZNF333	zinc finger protein 333 [Source:HGNC Symbol;Acc:HGNC:15624]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000160963	4.699	4.804	4.807	4.658	5.354	4.832	290	298	219	213	279	217	COL26A1	collagen type XXVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:18038]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24358	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	GO:0010811//positive regulation of cell-substrate adhesion	--
ENSG00000160972	13.299	13.878	14.701	14.65	14.415	15.339	790	828	645	636	721	663	PPP1R16A	protein phosphatase 1 regulatory subunit 16A [Source:HGNC Symbol;Acc:HGNC:14941]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0017020//myosin phosphatase regulator activity;GO:0019888//protein phosphatase regulator activity	GO:0035304//regulation of protein dephosphorylation;GO:0050790//regulation of catalytic activity	--
ENSG00000160973	0	0	0	0	0.073	0	0	0	0	0	2.59	0	FOXH1	forkhead box H1 [Source:HGNC Symbol;Acc:HGNC:3814]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0032444//activin responsive factor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0050681//androgen receptor binding;GO:0070410//co-SMAD binding;GO:0070412//R-SMAD binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001947//heart looping;GO:0003139//secondary heart field specification;GO:0003151//outflow tract morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007368//determination of left/right symmetry;GO:0009952//anterior/posterior pattern specification;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0035909//aorta morphogenesis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048318//axial mesoderm development;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0071345//cellular response to cytokine stimulus;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry"	Fork_head
ENSG00000160991	6.21	5.898	5.724	4.77	4.965	4.814	1383.31	1320.17	942	786.37	934.4	781.03	ORAI2	ORAI calcium release-activated calcium modulator 2 [Source:HGNC Symbol;Acc:HGNC:21667]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K16057	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone	GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity	GO:0002115//store-operated calcium entry;GO:0070588//calcium ion transmembrane transport	--
ENSG00000160993	5.935	6.528	5.258	6.7	6.997	7.147	235.69	271.83	162	190.63	238.6	209.97	ALKBH4	"alkB homolog 4, lysine demethylase [Source:HGNC Symbol;Acc:HGNC:21900]"	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0070938//contractile ring	GO:0003779//actin binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0032451//demethylase activity;GO:0035516//oxidative DNA demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0006325//chromatin organization;GO:0006482//protein demethylation;GO:0031032//actomyosin structure organization;GO:0035511//oxidative DNA demethylation;GO:0036090//cleavage furrow ingression;GO:0070988//demethylation;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:1902275//regulation of chromatin organization	--
ENSG00000160994	0	0	0	0	0	0	0	0	0	0	0	0	CCDC105	coiled-coil domain containing 105 [Source:HGNC Symbol;Acc:HGNC:26866]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000160999	1.186	1.502	1.285	1.514	1.276	1.689	55	70	44	52	50	57	SH2B2	SH2B adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:17381]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04910//Insulin signaling pathway;ko04722//Neurotrophin signaling pathway	K07193;K07193	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding	GO:0001922//B-1 B cell homeostasis;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008286//insulin receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0019222//regulation of metabolic process;GO:0030036//actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0046578//regulation of Ras protein signal transduction;GO:0050776//regulation of immune response;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050873//brown fat cell differentiation	--
ENSG00000161010	5.807	8.612	7.078	7.368	7.623	8.91	276.7	337.75	221.3	239.19	272.42	262.8	MRNIP	MRN complex interacting protein [Source:HGNC Symbol;Acc:HGNC:30817]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030870//Mre11 complex	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010212//response to ionizing radiation;GO:0045860//positive regulation of protein kinase activity;GO:0071168//protein localization to chromatin;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2001032//regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000161011	190.491	199.353	249.077	224.706	213.104	211.489	9274.07	10011.25	7458.55	8251.82	8712.76	7947.77	SQSTM1	sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Cell growth and death;Cell growth and death;Transport and catabolism;Cardiovascular disease;Development and regeneration;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05131//Shigellosis;ko04217//Necroptosis;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04137//Mitophagy - animal	K14381;K14381;K14381;K14381;K14381;K14381;K14381;K14381;K14381	GO:0000407//phagophore assembly site;GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016234//inclusion body;GO:0016235//aggresome;GO:0016605//PML body;GO:0030017//sarcomere;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044753//amphisome;GO:0044754//autolysosome;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece;GO:0097413//Lewy body	GO:0004674//protein serine/threonine kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035255//ionotropic glutamate receptor binding;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0001659//temperature homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006606//protein import into nucleus;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0007032//endosome organization;GO:0008104//protein localization;GO:0010821//regulation of mitochondrion organization;GO:0016197//endosomal transport;GO:0016236//macroautophagy;GO:0030154//cell differentiation;GO:0031397//negative regulation of protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0035973//aggrephagy;GO:0043065//positive regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046578//regulation of Ras protein signal transduction;GO:0061635//regulation of protein complex stability;GO:0061912//selective autophagy;GO:0070342//brown fat cell proliferation;GO:0097009//energy homeostasis;GO:0098780//response to mitochondrial depolarisation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000161013	92.325	87.883	88.587	94.922	89.911	92.166	4239	4206	3125	3301	3605	3187	MGAT4B	"alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B [Source:HGNC Symbol;Acc:HGNC:7048]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K00738;K00738;K00738	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006491//N-glycan processing;GO:0019082//viral protein processing;GO:0090284//positive regulation of protein glycosylation in Golgi	--
ENSG00000161016	809.034	861.352	832.444	1001.418	881.536	811.762	17201	18454	13058	15851	15919	12556	RPL8	ribosomal protein L8 [Source:HGNC Symbol;Acc:HGNC:10368]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02938;K02938	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0045202//synapse;GO:0098794//postsynapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000161021	10.25	10.639	10.743	10.032	11.615	11.239	1222	1275	946	886	1170	975	MAML1	mastermind like transcriptional coactivator 1 [Source:HGNC Symbol;Acc:HGNC:13632]	Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Immune system;Signal transduction	ko05165//Human papillomavirus infection;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06061;K06061;K06061	GO:0002193//MAML1-RBP-Jkappa- ICN1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042605//peptide antigen binding	GO:0003162//atrioventricular node development;GO:0006468//protein phosphorylation;GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0010831//positive regulation of myotube differentiation;GO:0045445//myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051149//positive regulation of muscle cell differentiation;GO:0060928//atrioventricular node cell development	--
ENSG00000161031	0	0	0	0	0	0	0	0	0	0	0	0	PGLYRP2	peptidoglycan recognition protein 2 [Source:HGNC Symbol;Acc:HGNC:30013]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0016019//peptidoglycan immune receptor activity;GO:0016787//hydrolase activity;GO:0042834//peptidoglycan binding;GO:0046872//metal ion binding	GO:0001519//peptide amidation;GO:0002376//immune system process;GO:0009253//peptidoglycan catabolic process;GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0051701//biological process involved in interaction with host	--
ENSG00000161036	10.154	11.425	10.334	10.748	12.504	10.91	421	440	306	331	390	322	LRWD1	leucine rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0035064//methylated histone binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0006325//chromatin organization;GO:0071169//establishment of protein localization to chromatin	--
ENSG00000161040	0.297	0.52	0.285	0.157	0.462	0.213	14	23	8	6	16	7	FBXL13	F-box and leucine rich repeat protein 13 [Source:HGNC Symbol;Acc:HGNC:21658]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0019005//SCF ubiquitin ligase complex;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000161048	6.059	3.963	4.856	5.086	5.063	4.925	528	361	370	312	385	315	NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D [Source:HGNC Symbol;Acc:HGNC:21683]	Organismal Systems	Nervous system	ko04723//Retrograde endocannabinoid signaling	K13985	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0042622//photoreceptor outer segment membrane;GO:0043227//membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0032052//bile acid binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0102200//N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity	GO:0001523//retinoid metabolic process;GO:0001659//temperature homeostasis;GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0048874//host-mediated regulation of intestinal microbiota composition;GO:0050729//positive regulation of inflammatory response;GO:0070291//N-acylethanolamine metabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process;GO:0090336//positive regulation of brown fat cell differentiation	--
ENSG00000161055	0.504	0.401	0.137	0.136	0.239	0	5	4	1	1	2	0	SCGB3A1	secretoglobin family 3A member 1 [Source:HGNC Symbol;Acc:HGNC:18384]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0030308//negative regulation of cell growth;GO:0042127//regulation of cell population proliferation;GO:1901741//positive regulation of myoblast fusion	--
ENSG00000161057	37.545	40.597	37.28	34.426	30.55	39.973	1598	1601	1040	1041	1122	1181	PSMC2	"proteasome 26S subunit, ATPase 2 [Source:HGNC Symbol;Acc:HGNC:9548]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03061;K03061;K03061;K03061;K03061;K03061;K03061;K03061;K03061	"GO:0000502//proteasome complex;GO:0000932//P-body;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034774//secretory granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043229//intracellular organelle;GO:1904813//ficolin-1-rich granule lumen"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0036402//proteasome-activating activity	GO:0001649//osteoblast differentiation;GO:0006261//DNA-dependent DNA replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030163//protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000161082	0.799	0.678	0.713	0.437	0.545	0.621	63	54	42	27	38	27	CELF5	CUGBP Elav-like family member 5 [Source:HGNC Symbol;Acc:HGNC:14058]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0036002//pre-mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing"	--
ENSG00000161091	11.458	12.723	12.474	15.125	14.412	16.002	440	520	379	437	477	419	MFSD12	major facilitator superfamily domain containing 12 [Source:HGNC Symbol;Acc:HGNC:28299]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0033229//cysteine transmembrane transporter activity	GO:0006865//amino acid transport;GO:0008643//carbohydrate transport;GO:0042438//melanin biosynthetic process;GO:0043474//pigment metabolic process involved in pigmentation;GO:0048021//regulation of melanin biosynthetic process;GO:0048022//negative regulation of melanin biosynthetic process;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:1903712//cysteine transmembrane transport	--
ENSG00000161179	5.991	5.84	6.002	7.674	6.004	7.111	167	165	124	159	144	144	YDJC	YdjC chitooligosaccharide deacetylase homolog [Source:HGNC Symbol;Acc:HGNC:27158]	-	-	-	-	-	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process	--
ENSG00000161180	0	0	0	0	0.051	0	0	0	0	0	2	0	CCDC116	coiled-coil domain containing 116 [Source:HGNC Symbol;Acc:HGNC:26688]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000161202	115.274	111.857	116.062	129.392	131.934	141.294	12152	12091	9096	10313	11812	11081	DVL3	dishevelled segment polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:3087]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma;ko04330//Notch signaling pathway	K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353;K02353	GO:0000785//chromatin;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0031267//small GTPase binding	"GO:0001934//positive regulation of protein phosphorylation;GO:0016055//Wnt signaling pathway;GO:0032880//regulation of protein localization;GO:0035556//intracellular signal transduction;GO:0035567//non-canonical Wnt signaling pathway;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0150012//positive regulation of neuron projection arborization"	--
ENSG00000161203	371.526	374.873	375.875	422.753	406.211	403.578	14996	15187	11166	12603	13818	11835	AP2M1	adaptor related protein complex 2 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:564]	Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K11826;K11826;K11826;K11826	GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030122//AP-2 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0036020//endolysosome membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035615//clathrin adaptor activity;GO:0044325//transmembrane transporter binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0097718//disordered domain specific binding	GO:0002092//positive regulation of receptor internalization;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006900//vesicle budding from membrane;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0031623//receptor internalization;GO:0034622//cellular protein-containing complex assembly;GO:0048488//synaptic vesicle endocytosis;GO:0065003//protein-containing complex assembly;GO:0072583//clathrin-dependent endocytosis;GO:0097494//regulation of vesicle size;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000161204	20.599	22.327	23.36	24.288	22.822	23.877	966	1061	830	834	943	854	ABCF3	ATP binding cassette subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:72]	-	-	-	-	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0045296//cadherin binding	GO:0051607//defense response to virus	--
ENSG00000161217	18.619	20.924	17.758	17.829	16.814	22.689	1656	1833.84	1379	1340	1433	1450.74	PCYT1A	"phosphate cytidylyltransferase 1A, choline [Source:HGNC Symbol;Acc:HGNC:8754]"	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K00968;K00968;K00968;K00968	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042587//glycogen granule	GO:0003824//catalytic activity;GO:0004105//choline-phosphate cytidylyltransferase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008289//lipid binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0031210//phosphatidylcholine binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0008654//phospholipid biosynthetic process;GO:0009058//biosynthetic process	--
ENSG00000161243	6.838	5.981	6.587	7.814	5.571	4.9	247	243	177	200	226	164	FBXO27	F-box protein 27 [Source:HGNC Symbol;Acc:HGNC:18753]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006516//glycoprotein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000161249	39.051	36.513	35.394	32.301	35.513	35.896	580	561	395	366	446	401	DMKN	dermokine [Source:HGNC Symbol;Acc:HGNC:25063]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:1903575//cornified envelope assembly	--
ENSG00000161265	3.699	4.32	1.781	3.018	3.61	3.736	38.78	64.67	20	33.13	44.26	40.49	U2AF1L4	U2 small nuclear RNA auxiliary factor 1 like 4 [Source:HGNC Symbol;Acc:HGNC:23020]	Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Transcription	ko05131//Shigellosis;ko03040//Spliceosome	K12836;K12836	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000161267	3.18	3.104	3.743	6.629	6.391	6.79	135	146	100	182	194	187	BDH1	3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:1027]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K00019;K00019	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0099617//matrix side of mitochondrial inner membrane	GO:0003824//catalytic activity;GO:0003858//3-hydroxybutyrate dehydrogenase activity;GO:0016491//oxidoreductase activity	GO:0006629//lipid metabolic process;GO:0008152//metabolic process	--
ENSG00000161270	0	0.038	0.035	0.012	0.078	0	0	3	2	1	6	0	NPHS1	"NPHS1 adhesion molecule, nephrin [Source:HGNC Symbol;Acc:HGNC:7908]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036057//slit diaphragm;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017022//myosin binding;GO:0050839//cell adhesion molecule binding	GO:0000165//MAPK cascade;GO:0007155//cell adhesion;GO:0007254//JNK cascade;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0007520//myoblast fusion;GO:0030838//positive regulation of actin filament polymerization;GO:0032836//glomerular basement membrane development;GO:0035418//protein localization to synapse;GO:0036060//slit diaphragm assembly;GO:0072015//glomerular visceral epithelial cell development;GO:0098609//cell-cell adhesion	--
ENSG00000161277	7.577	6.995	7.63	8.155	8.783	6.923	194	174	147	157	200	130	THAP8	THAP domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23191]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	THAP
ENSG00000161281	0	0	0	0.191	0	0	0	0	0	1	0	0	COX7A1	cytochrome c oxidase subunit 7A1 [Source:HGNC Symbol;Acc:HGNC:2287]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270;K02270	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity	"GO:0002082//regulation of oxidative phosphorylation;GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0097250//mitochondrial respirasome assembly;GO:1902600//proton transmembrane transport"	--
ENSG00000161298	3.308	2.442	2.307	2.232	1.629	2.511	150	107	82	84	80	93	ZNF382	zinc finger protein 382 [Source:HGNC Symbol;Acc:HGNC:17409]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000161328	1.203	1.11	1.369	1.036	1.507	1.078	69	64	58	44	73	45	LRRC56	leucine rich repeat containing 56 [Source:HGNC Symbol;Acc:HGNC:25430]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization	--
ENSG00000161381	0.747	0.168	0.063	0.156	0.082	0.032	13	9	2	5	3	1	PLXDC1	plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0021510//spinal cord development	--
ENSG00000161395	7.46	8.026	9.497	10.388	10.302	8.392	394	442	389	417	468	339	PGAP3	post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane	"GO:0005515//protein binding;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006505//GPI anchor metabolic process;GO:0006506//GPI anchor biosynthetic process	--
ENSG00000161405	0.005	0	0	0.007	0	0	1	0	0	1	0	0	IKZF3	IKAROS family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:13178]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007498//mesoderm development;GO:0009617//response to bacterium;GO:0030888//regulation of B cell proliferation;GO:0042113//B cell activation;GO:0042981//regulation of apoptotic process;GO:0045577//regulation of B cell differentiation;GO:0045619//regulation of lymphocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000161509	0.267	0.079	0.138	0.157	0.2	0.162	18	7	9	8	15	9	GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Neurodegenerative disease;Signal transduction;Substance dependence;Neurodegenerative disease;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211;K05211	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0022849//glutamate-gated calcium ion channel activity;GO:0038023//signaling receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0007420//brain development;GO:0009611//response to wounding;GO:0019722//calcium-mediated signaling;GO:0033058//directional locomotion;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0042177//negative regulation of protein catabolic process;GO:0042391//regulation of membrane potential;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0050885//neuromuscular process controlling balance;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098976//excitatory chemical synaptic transmission;GO:1903539//protein localization to postsynaptic membrane;GO:1904062//regulation of cation transmembrane transport;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000161513	1.139	2.318	2.867	2.064	1.384	2.211	39	59	67	39	42	40	FDXR	ferredoxin reductase [Source:HGNC Symbol;Acc:HGNC:3642]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	GO:0004324//ferredoxin-NADP+ reductase activity;GO:0015039//NADPH-adrenodoxin reductase activity;GO:0016491//oxidoreductase activity	GO:0006091//generation of precursor metabolites and energy;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006744//ubiquinone biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process	--
ENSG00000161526	56.08	49.565	49.087	46.72	40.343	36.062	1931	1859	1356	1238	1267	1078	SAP30BP	SAP30 binding protein [Source:HGNC Symbol;Acc:HGNC:30785]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0009615//response to virus;GO:0031065//positive regulation of histone deacetylation;GO:0052472//modulation by host of symbiont transcription"	--
ENSG00000161533	18.071	20.337	16.339	11.601	13.431	10.59	1473	1409	1015	695	827	652	ACOX1	acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine and metabolic disease;Global and overview maps;Transport and catabolism;Endocrine system;Global and overview maps;Lipid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko04936//Alcoholic liver disease;ko01200//Carbon metabolism;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko01040//Biosynthesis of unsaturated fatty acids;ko00592//alpha-Linolenic acid metabolism	K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232;K00232	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane	"GO:0003997//acyl-CoA oxidase activity;GO:0005504//fatty acid binding;GO:0016401//palmitoyl-CoA oxidase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0000038//very long-chain fatty acid metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006693//prostaglandin metabolic process;GO:0007283//spermatogenesis;GO:0009062//fatty acid catabolic process;GO:0016559//peroxisome fission;GO:0019395//fatty acid oxidation;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0042632//cholesterol homeostasis;GO:0050665//hydrogen peroxide biosynthetic process;GO:0055088//lipid homeostasis;GO:0140493//very long-chain fatty acid beta-oxidation	--
ENSG00000161542	12.365	12.841	11.628	13.486	11.743	11.128	532	512	373	406	431	335	PRPSAP1	phosphoribosyl pyrophosphate synthetase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:9466]	-	-	-	-	GO:0002189//ribose phosphate diphosphokinase complex;GO:0005737//cytoplasm	GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0043086//negative regulation of catalytic activity	--
ENSG00000161544	2.605	2.591	3.294	7.037	5.774	4.441	106	106	99	208	193	131	CYGB	cytoglobin [Source:HGNC Symbol;Acc:HGNC:16505]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0004096//catalase activity;GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0047888//fatty acid peroxidase activity	GO:0001666//response to hypoxia;GO:0006979//response to oxidative stress;GO:0010764//negative regulation of fibroblast migration;GO:0015671//oxygen transport;GO:0019395//fatty acid oxidation;GO:0032966//negative regulation of collagen biosynthetic process;GO:0098869//cellular oxidant detoxification;GO:2000490//negative regulation of hepatic stellate cell activation	--
ENSG00000161547	60.581	63.567	64.502	66.017	63.297	72.176	2451.56	2553.42	1949.53	1969.29	2169.38	2125.59	SRSF2	serine and arginine rich splicing factor 2 [Source:HGNC Symbol;Acc:HGNC:10783]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K12891;K12891	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000161551	6.477	3.533	3.551	2.529	5.721	3.738	120	91	85	71	101	75	ZNF577	zinc finger protein 577 [Source:HGNC Symbol;Acc:HGNC:28673]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000161558	1.383	2.101	1.912	5.006	2.12	1.959	65	91	56	85	77	67	TMEM143	transmembrane protein 143 [Source:HGNC Symbol;Acc:HGNC:25603]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000161594	0.024	0.075	0	0	0.137	0	1	1	0	0	3	0	KLHL10	kelch like family member 10 [Source:HGNC Symbol;Acc:HGNC:18829]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0000902//cell morphogenesis;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008584//male gonad development;GO:0009566//fertilization;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0048808//male genitalia morphogenesis;GO:0048873//homeostasis of number of cells within a tissue	--
ENSG00000161609	0	0	0	0	0	0	0	0	0	0	0	0	KASH5	KASH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26520]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005694//chromosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0090619//meiotic spindle pole"	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0070840//dynein complex binding	GO:0000724//double-strand break repair via homologous recombination;GO:0007015//actin filament organization;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0034397//telomere localization;GO:0048477//oogenesis;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle;GO:0051653//spindle localization;GO:0090172//microtubule cytoskeleton organization involved in homologous chromosome segregation;GO:0090220//chromosome localization to nuclear envelope involved in homologous chromosome segregation	--
ENSG00000161610	0	0	0	0	0	0	0	0	0	0	0	0	HCRT	hypocretin neuropeptide precursor [Source:HGNC Symbol;Acc:HGNC:4847]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05246	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse	GO:0005184//neuropeptide hormone activity;GO:0031771//type 1 hypocretin receptor binding;GO:0031772//type 2 hypocretin receptor binding	GO:0001659//temperature homeostasis;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007631//feeding behavior;GO:0008156//negative regulation of DNA replication;GO:0030431//sleep;GO:0042594//response to starvation;GO:0042755//eating behavior;GO:0043267//negative regulation of potassium ion transport;GO:0046928//regulation of neurotransmitter secretion;GO:0051928//positive regulation of calcium ion transport;GO:0051970//negative regulation of transmission of nerve impulse;GO:0051971//positive regulation of transmission of nerve impulse;GO:0060079//excitatory postsynaptic potential;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000161618	8.73	8.794	8.862	9.005	9.79	8.451	507	515	398	395	482	356	ALDH16A1	aldehyde dehydrogenase 16 family member A1 [Source:HGNC Symbol;Acc:HGNC:28114]	-	-	-	-	GO:0016020//membrane	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"	-	--
ENSG00000161634	0	0	0	0	0.33	0	0	0	0	0	3	0	DCD	dermcidin [Source:HGNC Symbol;Acc:HGNC:14669]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050832//defense response to fungus;GO:0051873//killing by host of symbiont cells	--
ENSG00000161638	10.073	10.101	8.54	8.622	9.01	9.152	888	895	556	563	671	587	ITGA5	integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cell motility;Transport and catabolism;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04145//Phagosome;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05100//Bacterial invasion of epithelial cells;ko05133//Pertussis;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484;K06484	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0032587//ruffle membrane;GO:0034674//integrin alpha5-beta1 complex;GO:0045202//synapse;GO:0071062//alphav-beta3 integrin-vitronectin complex	GO:0001618//virus receptor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	"GO:0001525//angiogenesis;GO:0007044//cell-substrate junction assembly;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007565//female pregnancy;GO:0007613//memory;GO:0010811//positive regulation of cell-substrate adhesion;GO:0023035//CD40 signaling pathway;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0033631//cell-cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0035313//wound healing, spreading of epidermal cells;GO:0035987//endodermal cell differentiation;GO:0045765//regulation of angiogenesis;GO:0046718//viral entry into host cell;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0098609//cell-cell adhesion;GO:1903672//positive regulation of sprouting angiogenesis;GO:2000811//negative regulation of anoikis"	--
ENSG00000161640	0	0	0	0	0	0	0	0	0	0	0	0	SIGLEC11	sialic acid binding Ig like lectin 11 [Source:HGNC Symbol;Acc:HGNC:15622]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0019902//phosphatase binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000161642	12.652	12.598	15.151	14.895	15.547	13.265	533	599	491	528	614	439	ZNF385A	zinc finger protein 385A [Source:HGNC Symbol;Acc:HGNC:17521]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body	GO:0002039//p53 binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007599//hemostasis;GO:0007611//learning or memory;GO:0007626//locomotory behavior;GO:0008298//intracellular mRNA localization;GO:0010609//mRNA localization resulting in posttranscriptional regulation of gene expression;GO:0030220//platelet formation;GO:0035855//megakaryocyte development;GO:0045600//positive regulation of fat cell differentiation;GO:0070889//platelet alpha granule organization;GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000765//regulation of cytoplasmic translation"	zf-C2H2
ENSG00000161643	0.05	0	0.034	0.05	0.015	0.017	4	0	2	3	1	1	-	-	-	-	-	-	-	-	-	-
ENSG00000161647	0.25	0.263	0.328	0.442	0.261	0.271	13	12	11	5	10	10	MPP3	membrane palmitoylated protein 3 [Source:HGNC Symbol;Acc:HGNC:7221]	-	-	-	-	GO:0005886//plasma membrane;GO:0005911//cell-cell junction	GO:0005515//protein binding;GO:0030165//PDZ domain binding	-	--
ENSG00000161649	0.017	0	0	0	0.062	0	1	0	0	0	3	0	CD300LG	CD300 molecule like family member g [Source:HGNC Symbol;Acc:HGNC:30455]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0032585//multivesicular body membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0002376//immune system process	--
ENSG00000161652	0	0	0	0	0	0	0	0	0	0	0	0	IZUMO2	IZUMO family member 2 [Source:HGNC Symbol;Acc:HGNC:28518]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000161653	0.616	0.545	0.463	0.493	0.864	0.752	27	24	15	16	32	24	NAGS	N-acetylglutamate synthase [Source:HGNC Symbol;Acc:HGNC:17996]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism	K11067;K11067;K11067;K11067	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004042//acetyl-CoA:L-glutamate N-acetyltransferase activity;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0034618//arginine binding;GO:0103045//methione N-acyltransferase activity	GO:0000050//urea cycle;GO:0006526//arginine biosynthetic process;GO:0006536//glutamate metabolic process	--
ENSG00000161654	12.957	14.453	13.598	10.213	11.924	12.489	671	747	527	388	509	481	LSM12	LSM12 homolog [Source:HGNC Symbol;Acc:HGNC:26407]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000161664	0.225	0.202	0.213	0.213	0.186	0.124	10	9	7	7	7	4	ASB16	ankyrin repeat and SOCS box containing 16 [Source:HGNC Symbol;Acc:HGNC:19768]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000161671	101.836	109.066	106.684	123.814	117.808	115.226	4329.51	4729.15	3368.42	3972.11	4255.92	3577.55	EMC10	ER membrane protein complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:27609]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0072546//EMC complex	GO:0032977//membrane insertase activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0045766//positive regulation of angiogenesis;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000161677	13.716	13.917	16.302	16.592	13.144	13.106	227	216	200	197	188	161	JOSD2	Josephin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28853]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination	--
ENSG00000161681	0.173	0.045	0.129	0.131	0.205	0.093	25	6	14	13	25	11	SHANK1	SH3 and multiple ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15474]	Organismal Systems	Nervous system	ko04724//Glutamatergic synapse	K15009	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0017124//SH3 domain binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030160//synaptic receptor adaptor activity;GO:0031877//somatostatin receptor binding;GO:0035255//ionotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0071532//ankyrin repeat binding;GO:0097110//scaffold protein binding	GO:0007399//nervous system development;GO:0007616//long-term memory;GO:0008306//associative learning;GO:0030154//cell differentiation;GO:0030534//adult behavior;GO:0032232//negative regulation of actin filament bundle assembly;GO:0035176//social behavior;GO:0035418//protein localization to synapse;GO:0042048//olfactory behavior;GO:0046959//habituation;GO:0050885//neuromuscular process controlling balance;GO:0050894//determination of affect;GO:0060013//righting reflex;GO:0060074//synapse maturation;GO:0060997//dendritic spine morphogenesis;GO:0060999//positive regulation of dendritic spine development;GO:0065003//protein-containing complex assembly;GO:0071625//vocalization behavior;GO:0099173//postsynapse organization;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000161682	27.049	25.989	32.429	32.702	32.016	36.555	1698	1633	1481	1538	1666	1686	FAM171A2	family with sequence similarity 171 member A2 [Source:HGNC Symbol;Acc:HGNC:30480]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000161692	1.016	1.384	1.377	1.469	1.123	1.066	62	75	54	58	59	47	DBF4B	DBF4 zinc finger B [Source:HGNC Symbol;Acc:HGNC:17883]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031431//Dbf4-dependent protein kinase complex;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0032147//activation of protein kinase activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1901987//regulation of cell cycle phase transition	--
ENSG00000161714	24.251	27.881	22.936	26.774	24.886	22.947	2985	3436	2107	2295	2419	2036	PLCD3	phospholipase C delta 3 [Source:HGNC Symbol;Acc:HGNC:9061]	Metabolism;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05131//Shigellosis;ko04919//Thyroid hormone signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K05857;K05857;K05857;K05857;K05857;K05857;K05857	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032154//cleavage furrow	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0042127//regulation of cell population proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0060716//labyrinthine layer blood vessel development	--
ENSG00000161791	0.707	0.981	0.783	0.562	0.583	0.702	99.95	139.02	74.81	56.78	74.89	69.84	FMNL3	formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0032794//GTPase activating protein binding;GO:0051015//actin filament binding	GO:0001525//angiogenesis;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0016043//cellular component organization;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization	--
ENSG00000161798	0.599	0.828	0.631	1.168	0.827	1.463	18	25	14	26	21	32	AQP5	aquaporin 5 [Source:HGNC Symbol;Acc:HGNC:638]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K09867	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015250//water channel activity;GO:0015267//channel activity;GO:0042802//identical protein binding	GO:0006833//water transport;GO:0015670//carbon dioxide transport;GO:0030157//pancreatic juice secretion;GO:0042476//odontogenesis;GO:0046541//saliva secretion;GO:0048593//camera-type eye morphogenesis;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0071476//cellular hypotonic response	--
ENSG00000161800	3.485	2.934	4.438	2.079	2.943	2.964	185	184	116	85	110	120	RACGAP1	Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow;GO:0051233//spindle midzone;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0090543//Flemming body;GO:0097149//centralspindlin complex	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0043014//alpha-tubulin binding;GO:0043015//gamma-tubulin binding;GO:0046872//metal ion binding;GO:0048487//beta-tubulin binding"	GO:0000281//mitotic cytokinesis;GO:0000915//actomyosin contractile ring assembly;GO:0006811//ion transport;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0007405//neuroblast proliferation;GO:0008272//sulfate transport;GO:0030154//cell differentiation;GO:0032467//positive regulation of cytokinesis;GO:0045995//regulation of embryonic development;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division;GO:0051988//regulation of attachment of spindle microtubules to kinetochore	--
ENSG00000161807	0	0	0	0	0	0	0	0	0	0	0	0	OR7G1	olfactory receptor family 7 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:8465]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000161813	18.831	14.736	12.186	11.618	14.75	15.178	1529	1304	922	837	922	972	LARP4	La ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:24320]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding	GO:0006412//translation;GO:0007010//cytoskeleton organization;GO:0010608//posttranscriptional regulation of gene expression;GO:0022604//regulation of cell morphogenesis;GO:0045727//positive regulation of translation	--
ENSG00000161835	2.188	3.267	3.061	4.309	4.363	3.603	73	94	57	95	111	73	TAMALIN	trafficking regulator and scaffold protein tamalin [Source:HGNC Symbol;Acc:HGNC:18707]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	"GO:0007165//signal transduction;GO:0008104//protein localization;GO:0099152//regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane"	--
ENSG00000161847	16.33	17.899	17.562	18.282	19.327	18.079	1177	1285.31	890.85	941	1180	916	RAVER1	"ribonucleoprotein, PTB binding 1 [Source:HGNC Symbol;Acc:HGNC:30296]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome"	--
ENSG00000161849	0	0	0	0	0	0	0	0	0	0	0	0	KRT84	keratin 84 [Source:HGNC Symbol;Acc:HGNC:6461]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005200//structural constituent of cytoskeleton;GO:0030280//structural constituent of skin epidermis	GO:0001942//hair follicle development;GO:0007010//cytoskeleton organization;GO:0035878//nail development;GO:0045616//regulation of keratinocyte differentiation	--
ENSG00000161850	0	0	0	0	0	0	0	0	0	0	0	0	KRT82	keratin 82 [Source:HGNC Symbol;Acc:HGNC:6459]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0008150//biological_process	--
ENSG00000161860	0.077	0.192	0	0.469	0	0.053	2	5	0	9	0	1	SYCE2	synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411]	-	-	-	-	GO:0000801//central element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007130//synaptonemal complex assembly;GO:0051301//cell division;GO:0051321//meiotic cell cycle	--
ENSG00000161888	0.45	0.33	0.283	0.18	0.267	1.087	8	8	5	3	4	15	SPC24	SPC24 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:26913]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0031262//Ndc80 complex;GO:0031617//NMS complex"	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051301//cell division	--
ENSG00000161896	2.973	2.667	2.95	2.521	2.371	2.812	150	134	100	94	106	102	IP6K3	inositol hexakisphosphate kinase 3 [Source:HGNC Symbol;Acc:HGNC:17269]	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K07756	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0000829//inositol heptakisphosphate kinase activity;GO:0000831//inositol hexakisphosphate 6-kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0052836//inositol 5-diphosphate pentakisphosphate 5-kinase activity;GO:0052839//inositol diphosphate tetrakisphosphate kinase activity"	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0040011//locomotion;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000161904	17.021	15.943	17.784	18.575	15.457	20.699	891	851	725	713	710	772	LEMD2	LEM domain nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:21244]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0031490//chromatin DNA binding	GO:0006998//nuclear envelope organization;GO:0022008//neurogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0035914//skeletal muscle cell differentiation;GO:0043409//negative regulation of MAPK cascade;GO:0051898//negative regulation of protein kinase B signaling;GO:0060914//heart formation;GO:0071168//protein localization to chromatin;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000161905	0	0.089	0	0.207	0.127	0	0	5	0	7	6	0	ALOX15	arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433]	Metabolism;Cellular Processes;Organismal Systems;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Cell growth and death;Nervous system;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04217//Necroptosis;ko04726//Serotonergic synapse;ko00590//Arachidonic acid metabolism;ko04216//Ferroptosis;ko00591//Linoleic acid metabolism	K00460;K00460;K00460;K00460;K00460;K00460	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	"GO:0004052//arachidonate 12(S)-lipoxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0016165//linoleate 13S-lipoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0050473//arachidonate 15-lipoxygenase activity;GO:0051213//dioxygenase activity"	GO:0001503//ossification;GO:0002820//negative regulation of adaptive immune response;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006954//inflammatory response;GO:0010811//positive regulation of cell-substrate adhesion;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0019395//fatty acid oxidation;GO:0030282//bone mineralization;GO:0030838//positive regulation of actin filament polymerization;GO:0034440//lipid oxidation;GO:0034976//response to endoplasmic reticulum stress;GO:0035358//regulation of peroxisome proliferator activated receptor signaling pathway;GO:0035963//cellular response to interleukin-13;GO:0042060//wound healing;GO:0042759//long-chain fatty acid biosynthetic process;GO:0043277//apoptotic cell clearance;GO:0043651//linoleic acid metabolic process;GO:0050727//regulation of inflammatory response;GO:0051122//hepoxilin biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071277//cellular response to calcium ion;GO:1901074//regulation of engulfment of apoptotic cell;GO:2001303//lipoxin A4 biosynthetic process	--
ENSG00000161911	0	0	0	0	0	0	0	0	0	0	0	0	TREML1	triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031091//platelet alpha granule	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0019722//calcium-mediated signaling;GO:0030168//platelet activation;GO:0045087//innate immune response	--
ENSG00000161914	4.391	4.318	4.79	4.311	4.457	3.737	119	130	112	114	110	93	ZNF653	zinc finger protein 653 [Source:HGNC Symbol;Acc:HGNC:25196]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0050682//AF-2 domain binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:1900116//extracellular negative regulation of signal transduction;GO:1903507//negative regulation of nucleic acid-templated transcription"	zf-C2H2
ENSG00000161920	10.174	12.086	12.586	8.83	10.415	9.394	176	210	161	113	152	118	MED11	mediator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:32687]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000161921	23.474	27.728	22.009	25.417	28.067	22.904	1113	1305	750	887	1121	778	CXCL16	C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway	K10035;K10035	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005044//scavenger receptor activity;GO:0005125//cytokine activity;GO:0008009//chemokine activity	GO:0006898//receptor-mediated endocytosis;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0010818//T cell chemotaxis;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0034097//response to cytokine;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:0048247//lymphocyte chemotaxis	--
ENSG00000161929	0	0	0	0	0	0	0	0	0	0	0	0	SCIMP	SLP adaptor and CSK interacting membrane protein [Source:HGNC Symbol;Acc:HGNC:33504]	-	-	-	-	GO:0001726//ruffle;GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030175//filopodium;GO:0031256//leading edge membrane;GO:0031259//uropod membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045335//phagocytic vesicle;GO:0097197//tetraspanin-enriched microdomain	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034154//toll-like receptor 7 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071226//cellular response to molecule of fungal origin	--
ENSG00000161939	0	0.444	0.849	0	0	0	0	8.34	11.71	0	0	0	RNASEK-C17orf49	RNASEK-C17orf49 readthrough [Source:HGNC Symbol;Acc:HGNC:44419]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016589//NURF complex;GO:0071339//MLL1 complex	-	-	--
ENSG00000161940	0	0	0	0	0.016	0	0	0	0	0	1	0	BCL6B	BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001817//regulation of cytokine production;GO:0002682//regulation of immune system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0042092//type 2 immune response;GO:0042127//regulation of cell population proliferation;GO:0045595//regulation of cell differentiation;GO:0050727//regulation of inflammatory response	ZBTB
ENSG00000161944	0	0	0	0	0	0	0	0	0	0	0	0	ASGR2	asialoglycoprotein receptor 2 [Source:HGNC Symbol;Acc:HGNC:743]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K10064	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0048471//perinuclear region of cytoplasm	GO:0004873//asialoglycoprotein receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006897//endocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0009100//glycoprotein metabolic process;GO:0030282//bone mineralization;GO:0031647//regulation of protein stability;GO:0055088//lipid homeostasis	--
ENSG00000161955	8.099	10.84	12.847	12.504	12.926	8.755	283	350	322	282	357	232	TNFSF13	TNF superfamily member 13 [Source:HGNC Symbol;Acc:HGNC:11928]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Immune disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05323//Rheumatoid arthritis;ko04672//Intestinal immune network for IgA production	K05475;K05475;K05475	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0002376//immune system process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0048298//positive regulation of isotype switching to IgA isotypes	--
ENSG00000161956	23.301	25.811	26.921	27.099	25.975	27.697	1191.52	1306	1019.61	1041.28	1074	989.53	SENP3	SUMO specific peptidase 3 [Source:HGNC Symbol;Acc:HGNC:17862]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0071339//MLL1 complex	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070140//SUMO-specific isopeptidase activity	GO:0006508//proteolysis;GO:0016926//protein desumoylation	--
ENSG00000161958	16.208	17.684	14.891	15.326	17.765	14.686	788	865	546	573	744	532	FGF11	fibroblast growth factor 11 [Source:HGNC Symbol;Acc:HGNC:3667]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0017080//sodium channel regulator activity	GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:1905150//regulation of voltage-gated sodium channel activity	--
ENSG00000161960	198.343	203.491	199.236	188.188	186.186	176.324	5810.37	6055	4252.9	4284.16	4703	3843.07	EIF4A1	eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0000339//RNA cap binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008135//translation factor activity, RNA binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity"	GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000161970	556.936	615.739	553.93	498.658	433.616	441.345	6120	6798	4494	4056	4026	3527	RPL26	ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02898;K02898	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding	"GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0010467//gene expression;GO:0034644//cellular response to UV;GO:0042273//ribosomal large subunit biogenesis;GO:0045727//positive regulation of translation;GO:0071480//cellular response to gamma radiation;GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:1902167//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1904803//regulation of translation involved in cellular response to UV"	--
ENSG00000161973	0.105	0	0.095	0.095	0.083	0.145	3	0	2	2	2	3	CCDC42	coiled-coil domain containing 42 [Source:HGNC Symbol;Acc:HGNC:26528]	-	-	-	-	-	GO:0005515//protein binding	GO:0007286//spermatid development	--
ENSG00000161980	3.057	2.902	3.473	3.51	3.161	4.395	87	83	73	74	76	91	POLR3K	RNA polymerase III subunit K [Source:HGNC Symbol;Acc:HGNC:14121]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03019;K03019	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006351//transcription, DNA-templated;GO:0006383//transcription by RNA polymerase III;GO:0006386//termination of RNA polymerase III transcription;GO:0042779//tRNA 3'-trailer cleavage;GO:0045087//innate immune response;GO:0051607//defense response to virus"	--
ENSG00000161981	14.086	14.677	13.657	16.437	14.3	12.214	317	332	227	274	255	200	SNRNP25	small nuclear ribonucleoprotein U11/U12 subunit 25 [Source:HGNC Symbol;Acc:HGNC:14161]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000161992	0	0.021	0	0	0	0	0	1	0	0	0	0	PRR35	proline rich 35 [Source:HGNC Symbol;Acc:HGNC:14139]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000161996	2.781	3.085	2.806	2.146	3.107	2.203	273	305	203	176	225	168	WDR90	WD repeat domain 90 [Source:HGNC Symbol;Acc:HGNC:26960]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000161999	44.556	48.223	42.918	47.117	44.701	45.053	1433.03	1496.24	1073.57	1167.69	1228.88	1144.65	JMJD8	jumonji domain containing 8 [Source:HGNC Symbol;Acc:HGNC:14148]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding	GO:0006110//regulation of glycolytic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1903302//regulation of pyruvate kinase activity;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000162004	0.628	0.927	0.494	0.205	0.216	0.209	15	22	12	5	6	5	CCDC78	coiled-coil domain containing 78 [Source:HGNC Symbol;Acc:HGNC:14153]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0042383//sarcolemma;GO:0048471//perinuclear region of cytoplasm;GO:0098536//deuterosome	-	GO:0003009//skeletal muscle contraction;GO:0030030//cell projection organization;GO:0098535//de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	--
ENSG00000162006	0	0	0	0	0	0	0	0	0	0	0	0	MSLNL	mesothelin like [Source:HGNC Symbol;Acc:HGNC:14170]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	-	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion	--
ENSG00000162009	0.055	0	0.025	0.099	0.022	0.101	3	0	1	4	1	4	SSTR5	somatostatin receptor 5 [Source:HGNC Symbol;Acc:HGNC:11334]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K04221;K04221;K04221	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004994//somatostatin receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0032467//positive regulation of cytokinesis;GO:0038170//somatostatin signaling pathway;GO:0042593//glucose homeostasis;GO:0050796//regulation of insulin secretion;GO:0071385//cellular response to glucocorticoid stimulus"	--
ENSG00000162032	14.278	15.01	14.612	12.827	13.797	14.389	449.96	480.36	343.6	291.79	371.14	333.33	SPSB3	splA/ryanodine receptor domain and SOCS box containing 3 [Source:HGNC Symbol;Acc:HGNC:30629]	-	-	-	-	GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000162039	0.082	0.207	0.187	0.109	0.127	0.464	3.17	8	5	3	4	13	MEIOB	meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0016787//hydrolase activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0000724//double-strand break repair via homologous recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0007140//male meiotic nuclear division;GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0009566//fertilization;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000162040	0	0	0	0	0	0	0	0	0	0	0	0	HS3ST6	heparan sulfate-glucosamine 3-sulfotransferase 6 [Source:HGNC Symbol;Acc:HGNC:14178]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity	GO:0001835//blastocyst hatching;GO:0006024//glycosaminoglycan biosynthetic process	--
ENSG00000162062	1.537	1.6	1.83	1.163	0.712	1.349	43	42	33	30	22	25	TEDC2	tubulin epsilon and delta complex 2 [Source:HGNC Symbol;Acc:HGNC:25849]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000162063	0.729	0.896	0.91	0.569	0.85	0.627	64	79	59	37	63	40	CCNF	cyclin F [Source:HGNC Symbol;Acc:HGNC:1591]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0019005//SCF ubiquitin ligase complex;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0010997//anaphase-promoting complex binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000320//re-entry into mitotic cell cycle;GO:0001890//placenta development;GO:0007049//cell cycle;GO:0010826//negative regulation of centrosome duplication;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000162065	2.234	2.235	1.783	2.105	1.972	1.755	212	218	128	139	168	155	TBC1D24	TBC1 domain family member 24 [Source:HGNC Symbol;Acc:HGNC:29203]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0098793//presynapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0031175//neuron projection development;GO:0036475//neuron death in response to oxidative stress;GO:0050790//regulation of catalytic activity	--
ENSG00000162066	9.205	9.896	9.419	10.998	9.567	9.749	475	557	376	451.99	460	409	AMDHD2	amidohydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24262]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01443;K01443	GO:0005634//nucleus;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0008448//N-acetylglucosamine-6-phosphate deacetylase activity;GO:0016787//hydrolase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0046872//metal ion binding;GO:0047419//N-acetylgalactosamine-6-phosphate deacetylase activity"	GO:0005975//carbohydrate metabolic process;GO:0006040//amino sugar metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0019262//N-acetylneuraminate catabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000162068	0.331	0.614	0.597	0.476	0.809	0.333	15	28	20	16	31	11	NTN3	netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06844	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005794//Golgi apparatus	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016358//dendrite development	--
ENSG00000162069	0	0	0	0	0	0	0	0	0	0	0	0	BICDL2	BICD family like cargo adaptor 2 [Source:HGNC Symbol;Acc:HGNC:33584]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0047496//vesicle transport along microtubule;GO:0055107//Golgi to secretory granule transport	--
ENSG00000162073	116.567	124.726	118.497	114.635	112.074	128.269	6334.95	6906	4834.97	4682.98	5245.91	5045.98	PAQR4	progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0038023//signaling receptor activity	-	--
ENSG00000162076	15.2	18.659	21.565	21.116	22.078	21.779	296	374	306	298	376	321	FLYWCH2	FLYWCH family member 2 [Source:HGNC Symbol;Acc:HGNC:25178]	-	-	-	-	GO:0005575//cellular_component	GO:0003723//RNA binding	GO:0008150//biological_process	--
ENSG00000162078	0.07	0	0.246	0.089	0.155	0	1	0	3	2	4	0	ZG16B	zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0001895//retina homeostasis	--
ENSG00000162086	5.321	5.128	5.256	4.68	5.233	4.991	230	222	145	135	172	152	ZNF75A	zinc finger protein 75a [Source:HGNC Symbol;Acc:HGNC:13146]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000162104	6.23	7.281	9.374	7.553	9.606	8.203	1006	1015	926	807	1056	832	ADCY9	adenylate cyclase 9 [Source:HGNC Symbol;Acc:HGNC:240]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system;Excretory system;Infectious disease: bacterial;Excretory system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko04962//Vasopressin-regulated water reabsorption"	K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049;K08049	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0006171//cAMP biosynthetic process;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway	--
ENSG00000162105	15.646	13.483	13.223	8.888	11.412	12.132	2935	2657	1970	1326	1891	1796	SHANK2	SH3 and multiple ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:14295]	Organismal Systems	Nervous system	ko04724//Glutamatergic synapse	K15009	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030426//growth cone;GO:0031526//brush border membrane;GO:0032279//asymmetric synapse;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048786//presynaptic active zone;GO:0060170//ciliary membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0017124//SH3 domain binding;GO:0030160//synaptic receptor adaptor activity;GO:0035255//ionotropic glutamate receptor binding;GO:0098919//structural constituent of postsynaptic density	GO:0007416//synapse assembly;GO:0007420//brain development;GO:0007584//response to nutrient;GO:0007612//learning;GO:0008284//positive regulation of cell population proliferation;GO:0008306//associative learning;GO:0008344//adult locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0035331//negative regulation of hippo signaling;GO:0050807//regulation of synapse organization;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0071625//vocalization behavior;GO:0099562//maintenance of postsynaptic density structure	--
ENSG00000162129	6.594	6.992	8.705	7.583	9.16	7.499	492	538	423	387	455	367	CLPB	caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664]	Organismal Systems	Aging	ko04213//Longevity regulating pathway - multiple species	K03695	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0034605//cellular response to heat;GO:0039529//RIG-I signaling pathway;GO:0140374//antiviral innate immune response	--
ENSG00000162139	2.851	2.818	2.989	2.869	2.301	3.286	305	307	238	241	234	218	NEU3	neuraminidase 3 [Source:HGNC Symbol;Acc:HGNC:7760]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K12357;K12357;K12357	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane	"GO:0004308//exo-alpha-sialidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016997//alpha-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052796//exo-alpha-(2->8)-sialidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0016042//lipid catabolic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:1900186//negative regulation of clathrin-dependent endocytosis	--
ENSG00000162144	18.97	17.892	18.077	19.687	21.424	18.836	775.15	771.79	603.42	644.97	740.24	625.74	CYB561A3	cytochrome b561 family member A3 [Source:HGNC Symbol;Acc:HGNC:23014]	-	-	-	-	GO:0005730//nucleolus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0140571//transmembrane ascorbate ferrireductase activity	GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport	--
ENSG00000162148	0.241	0.443	0.528	0.346	0.699	0.31	7	8	9	5	12	6.89	PPP1R32	protein phosphatase 1 regulatory subunit 32 [Source:HGNC Symbol;Acc:HGNC:28869]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0019902//phosphatase binding	-	--
ENSG00000162174	11.092	10.162	11.456	8.56	9.026	7.147	378	380	273	233	298	233	ASRGL1	asparaginase and isoaspartyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:16448]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism"	K13051;K13051	GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004067//asparaginase activity;GO:0008233//peptidase activity;GO:0008798//beta-aspartyl-peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0033345//asparagine catabolic process via L-aspartate	--
ENSG00000162188	0.223	0	0.378	0.075	0.264	0.077	4	0	5	1	4	1	GNG3	G protein subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:4405]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540;K04540	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030425//dendrite;GO:0044297//cell body	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration	--
ENSG00000162191	62.886	64.565	68.103	69.66	59.32	68.958	1460	1482	1162	1202	1177	1162	UBXN1	UBX domain protein 1 [Source:HGNC Symbol;Acc:HGNC:18402]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K24348	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0051117//ATPase binding;GO:0071796//K6-linked polyubiquitin modification-dependent protein binding;GO:1904855//proteasome regulatory particle binding	GO:0031397//negative regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1903094//negative regulation of protein K48-linked deubiquitination;GO:1904293//negative regulation of ERAD pathway;GO:2000157//negative regulation of ubiquitin-specific protease activity	--
ENSG00000162194	2.089	1.692	1.045	1.498	1.49	2.079	54.57	54.67	32.43	53.63	54.38	54.45	LBHD1	LBH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28351]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000162222	10.753	10.437	12.148	11.353	10.94	12.556	251	238	189	191	221	211	TTC9C	tetratricopeptide repeat domain 9C [Source:HGNC Symbol;Acc:HGNC:28432]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162227	10.437	9.143	10.335	10.649	11.789	12.094	341	347	271	331	341	328	TAF6L	TATA-box binding protein associated factor 6 like [Source:HGNC Symbol;Acc:HGNC:17305]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03131	GO:0000118//histone deacetylase complex;GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0046695//SLIK (SAGA-like) complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046982//protein heterodimerization activity	"GO:0006282//regulation of DNA repair;GO:0006338//chromatin remodeling;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:1904672//regulation of somatic stem cell population maintenance"	--
ENSG00000162231	18.534	17.635	21.965	21.451	22.78	22.858	1030	980	933	872	1041	871	NXF1	nuclear RNA export factor 1 [Source:HGNC Symbol;Acc:HGNC:8071]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14284;K14284;K14284;K14284;K14284;K14284	GO:0000346//transcription export complex;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016607//nuclear speck;GO:0042272//nuclear RNA export factor complex;GO:0042405//nuclear inclusion body;GO:0110165//cellular anatomical entity	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000162236	23.04	23.247	22.859	21.932	22.473	23.262	844	825	612	589	684	602	STX5	syntaxin 5 [Source:HGNC Symbol;Acc:HGNC:11440]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08490	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0031982//vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0047485//protein N-terminus binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0034498//early endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0045732//positive regulation of protein catabolic process;GO:0048278//vesicle docking;GO:0048280//vesicle fusion with Golgi apparatus;GO:0090166//Golgi disassembly;GO:1903358//regulation of Golgi organization"	--
ENSG00000162241	0.913	0.397	0.681	0.614	0.766	0.438	35	19	22	17	20	15	SLC25A45	solute carrier family 25 member 45 [Source:HGNC Symbol;Acc:HGNC:27442]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015227//acyl carnitine transmembrane transporter activity	GO:0006844//acyl carnitine transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:1902616//acyl carnitine transmembrane transport	--
ENSG00000162244	282.453	300.802	289.815	316.684	258.336	255.619	4418	4727	3347	3666	3412	2909	RPL29	ribosomal protein L29 [Source:HGNC Symbol;Acc:HGNC:10331]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02905;K02905	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0008201//heparin binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0007566//embryo implantation	--
ENSG00000162267	0.765	1.046	0.887	1.373	0.914	0.984	45	61	38	59	45	42	ITIH3	inter-alpha-trypsin inhibitor heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:6168]	-	-	-	-	GO:0005576//extracellular region;GO:0031089//platelet dense granule lumen;GO:0070062//extracellular exosome	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process	--
ENSG00000162298	13.629	16.818	16.521	14.952	19.866	16.379	827	986	743	700	978	752	SYVN1	synoviolin 1 [Source:HGNC Symbol;Acc:HGNC:20738]	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K10601;K10601	GO:0000836//Hrd1p ubiquitin ligase complex;GO:0000839//Hrd1p ubiquitin ligase ERAD-L complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0051117//ATPase binding;GO:0061630//ubiquitin protein ligase activity;GO:0140297//DNA-binding transcription factor binding;GO:1990381//ubiquitin-specific protease binding	"GO:0002327//immature B cell differentiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0036503//ERAD pathway;GO:0050821//protein stabilization;GO:0070936//protein K48-linked ubiquitination;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1904380//endoplasmic reticulum mannose trimming"	--
ENSG00000162300	18.742	20.75	18.954	23.728	21.32	19.224	504	554	385	469	486	376	ZFPL1	zinc finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:12868]	-	-	-	-	GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0016192//vesicle-mediated transport"	--
ENSG00000162302	10.484	11.548	13.704	16.47	16.308	14.981	653	733	618	767	818	686	RPS6KA4	ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04668//TNF signaling pathway	K16510;K16510	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0001818//negative regulation of cytokine production;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033129//positive regulation of histone phosphorylation;GO:0035066//positive regulation of histone acetylation;GO:0035556//intracellular signal transduction;GO:0043987//histone H3-S10 phosphorylation;GO:0043988//histone H3-S28 phosphorylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070498//interleukin-1-mediated signaling pathway"	--
ENSG00000162337	22.546	23.867	26.688	25.987	29.442	27.185	2421	2576	2091	2067	2671	2124	LRP5	LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: specific types;Signal transduction;Cancer: specific types;Cancer: specific types;Endocrine system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04928//Parathyroid hormone synthesis, secretion and action"	K03068;K03068;K03068;K03068;K03068;K03068;K03068;K03068;K03068	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:1990851//Wnt-Frizzled-LRP5/6 complex;GO:1990909//Wnt signalosome	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0017147//Wnt-protein binding;GO:0042813//Wnt-activated receptor activity;GO:0071936//coreceptor activity involved in Wnt signaling pathway;GO:1904928//coreceptor activity involved in canonical Wnt signaling pathway	"GO:0001702//gastrulation with mouth forming second;GO:0001944//vasculature development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002076//osteoblast development;GO:0006007//glucose catabolic process;GO:0006897//endocytosis;GO:0008203//cholesterol metabolic process;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0016055//Wnt signaling pathway;GO:0033690//positive regulation of osteoblast proliferation;GO:0035019//somatic stem cell population maintenance;GO:0035108//limb morphogenesis;GO:0035426//extracellular matrix-cell signaling;GO:0042074//cell migration involved in gastrulation;GO:0042632//cholesterol homeostasis;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046849//bone remodeling;GO:0048539//bone marrow development;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060033//anatomical structure regression;GO:0060042//retina morphogenesis in camera-type eye;GO:0060070//canonical Wnt signaling pathway;GO:0060348//bone development;GO:0060349//bone morphogenesis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060603//mammary gland duct morphogenesis;GO:0060612//adipose tissue development;GO:0060764//cell-cell signaling involved in mammary gland development;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0061304//retinal blood vessel morphogenesis;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0110135//Norrin signaling pathway;GO:1902262//apoptotic process involved in blood vessel morphogenesis"	--
ENSG00000162341	0.951	1.344	1.895	1.146	1.216	1.72	85.35	113.19	116	79	87.46	106	TPCN2	two pore segment channel 2 [Source:HGNC Symbol;Acc:HGNC:20820]	Environmental Information Processing;Organismal Systems	Signal transduction;Digestive system	ko04020//Calcium signaling pathway;ko04972//Pancreatic secretion	K14077;K14077	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0036020//endolysosome membrane	"GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0019901//protein kinase binding;GO:0022832//voltage-gated channel activity;GO:0042802//identical protein binding;GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0097682//intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006939//smooth muscle contraction;GO:0007040//lysosome organization;GO:0010506//regulation of autophagy;GO:0017157//regulation of exocytosis;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0019722//calcium-mediated signaling;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0075509//endocytosis involved in viral entry into host cell;GO:0090117//endosome to lysosome transport of low-density lipoprotein particle	--
ENSG00000162344	0.026	0.132	0.179	0	0	0	1	5	5	0	0	0	FGF19	fibroblast growth factor 19 [Source:HGNC Symbol;Acc:HGNC:3675]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K22603;K22603;K22603;K22603;K22603;K22603;K22603;K22603;K22603;K22603	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0007399//nervous system development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009617//response to bacterium;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0045471//response to ethanol;GO:0046326//positive regulation of glucose import;GO:0046330//positive regulation of JNK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070858//negative regulation of bile acid biosynthetic process	--
ENSG00000162365	0	0	0	0	0	0	0	0	0	0	0	0	CYP4A22	cytochrome P450 family 4 subfamily A member 22 [Source:HGNC Symbol;Acc:HGNC:20575]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0018685//alkane 1-monooxygenase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0102033//long-chain fatty acid omega-hydroxylase activity;GO:0102116//laurate hydroxylase activity;GO:0103002//16-hydroxypalmitate dehydrogenase activity"	GO:0001822//kidney development;GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0043651//linoleic acid metabolic process;GO:0046456//icosanoid biosynthetic process;GO:0048252//lauric acid metabolic process	--
ENSG00000162366	0.345	0.801	0.701	0	0.477	0.086	6	14	9	0	7	1	PDZK1IP1	PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000162367	0	0.01	0	0	0	0	0	1	0	0	0	0	TAL1	"TAL bHLH transcription factor 1, erythroid differentiation factor [Source:HGNC Symbol;Acc:HGNC:11556]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0042826//histone deacetylase binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007626//locomotory behavior;GO:0021527//spinal cord association neuron differentiation;GO:0030097//hemopoiesis;GO:0030099//myeloid cell differentiation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0030220//platelet formation;GO:0030221//basophil differentiation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0035162//embryonic hemopoiesis;GO:0035855//megakaryocyte development;GO:0042127//regulation of cell population proliferation;GO:0043249//erythrocyte maturation;GO:0045165//cell fate commitment;GO:0045637//regulation of myeloid cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045799//positive regulation of chromatin assembly or disassembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048699//generation of neurons;GO:0051781//positive regulation of cell division;GO:0060018//astrocyte fate commitment;GO:0060216//definitive hemopoiesis;GO:0060217//hemangioblast cell differentiation;GO:0060218//hematopoietic stem cell differentiation;GO:0060375//regulation of mast cell differentiation;GO:2000036//regulation of stem cell population maintenance"	bHLH
ENSG00000162368	45.529	38.468	40.634	32.635	34.909	36.5	2716	2319	1782	1462	1688	1583	CMPK1	cytidine/uridine monophosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18170]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K13800;K13800;K13800	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004849//uridine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009041//uridylate kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0033862//UMP kinase activity;GO:0036430//CMP kinase activity;GO:0036431//dCMP kinase activity;GO:0050145//nucleoside monophosphate kinase activity"	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006222//UMP biosynthetic process;GO:0006225//UDP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0009220//pyrimidine ribonucleotide biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046705//CDP biosynthetic process;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000162373	2.563	2.323	2.391	2.806	2.326	2.27	90	82	62	73	69	58	BEND5	BEN domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25668]	-	-	-	-	GO:0005794//Golgi apparatus	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000162374	0	0	0	0	0	0	0	0	0	0	0	0	ELAVL4	ELAV like RNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:3315]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042788//polysomal ribosome;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0098978//glutamatergic synapse;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0045182//translation regulator activity;GO:0097158//pre-mRNA intronic pyrimidine-rich binding	"GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0007568//aging;GO:0007612//learning;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0008380//RNA splicing;GO:0021895//cerebral cortex neuron differentiation;GO:0030182//neuron differentiation;GO:0031099//regeneration;GO:0034976//response to endoplasmic reticulum stress;GO:0042220//response to cocaine;GO:0043488//regulation of mRNA stability;GO:0048813//dendrite morphogenesis;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0099547//regulation of translation at synapse, modulating synaptic transmission;GO:1900006//positive regulation of dendrite development;GO:1905870//positive regulation of 3'-UTR-mediated mRNA stabilization;GO:1990090//cellular response to nerve growth factor stimulus"	--
ENSG00000162377	4.207	4.558	4.747	4.766	4.379	5.832	348	379	290	292	306	351	COA7	cytochrome c oxidase assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:25716]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18180	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding	-	--
ENSG00000162378	11.527	9.448	10.47	8.281	9.1	10.481	1947	1604	1247	1036	1266	1288	ZYG11B	"zyg-11 family member B, cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:25820]"	-	-	-	-	GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0030162//regulation of proteolysis;GO:0031331//positive regulation of cellular catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000162383	0.814	0.649	0.533	0.531	0.465	0.392	44	38	23	22	22	16	SLC1A7	solute carrier family 1 member 7 [Source:HGNC Symbol;Acc:HGNC:10945]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle	K05618;K05618	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098793//presynapse	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015501//glutamate:sodium symporter activity	GO:0001504//neurotransmitter uptake;GO:0006811//ion transport;GO:0006835//dicarboxylic acid transport;GO:0006836//neurotransmitter transport;GO:0015711//organic anion transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0015813//L-glutamate transmembrane transport;GO:0055085//transmembrane transport;GO:0098810//neurotransmitter reuptake;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000162384	16.581	16.322	17.06	19.136	17.606	16.415	379	375	288	324	340	273	CZIB	CXXC motif containing zinc binding protein [Source:HGNC Symbol;Acc:HGNC:26059]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008150//biological_process	--
ENSG00000162385	8.005	9.519	9.427	8.019	4.164	6.555	104	127	92	79	45	64	MAGOH	"mago homolog, exon junction complex subunit [Source:HGNC Symbol;Acc:HGNC:6815]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12877;K12877;K12877	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0071013//catalytic step 2 spliceosome;GO:1990501//exon-exon junction subcomplex mago-y14	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0008380//RNA splicing;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:2000622//regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000162390	16.258	18.137	21.2	27.519	29.173	23.502	1067.13	1184.34	1017.92	1339.34	1607.5	1110.33	ACOT11	acyl-CoA thioesterase 11 [Source:HGNC Symbol;Acc:HGNC:18156]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0036042//long-chain fatty acyl-CoA binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0052816//long-chain acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0009266//response to temperature stimulus;GO:0009409//response to cold;GO:0035556//intracellular signal transduction;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000162391	0.037	0.162	0.049	0.187	0.041	0.09	1.11	6.66	1.08	5.66	1.04	2.67	FAM151A	family with sequence similarity 151 member A [Source:HGNC Symbol;Acc:HGNC:25032]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000162396	2.681	3.176	2.771	3.149	3.536	3.459	131	156	100	114	146	123	PARS2	"prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563]"	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01881	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004827//proline-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006433//prolyl-tRNA aminoacylation	--
ENSG00000162398	0	0	0	0	0	0	0	0	0	0	0	0	LEXM	lymphocyte expansion molecule [Source:HGNC Symbol;Acc:HGNC:26854]	-	-	-	-	-	-	-	--
ENSG00000162399	0	0	0	0	0	0	0	0	0	0	0	0	BSND	barttin CLCNK type accessory subunit beta [Source:HGNC Symbol;Acc:HGNC:16512]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0017081//chloride channel regulator activity	GO:0006821//chloride transport	--
ENSG00000162402	7.026	5.17	6.032	4.568	5.3	6.448	1574	1164	998	758	1003	1051	USP24	ubiquitin specific peptidase 24 [Source:HGNC Symbol;Acc:HGNC:12623]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000162407	12.255	12.735	16.015	11.852	12.815	17.714	832	869	803	596	735	875	PLPP3	phospholipid phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:9229]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Immune system;Cancer: overview;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism;ko04975//Fat digestion and absorption	K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0045121//membrane raft;GO:0070971//endoplasmic reticulum exit site	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0106235//ceramide-1-phosphate phosphatase activity	"GO:0001933//negative regulation of protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0006672//ceramide metabolic process;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030148//sphingolipid biosynthetic process;GO:0033631//cell-cell adhesion mediated by integrin;GO:0034109//homotypic cell-cell adhesion;GO:0044328//canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration;GO:0044329//canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion;GO:0044330//canonical Wnt signaling pathway involved in positive regulation of wound healing;GO:0046839//phospholipid dephosphorylation;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060070//canonical Wnt signaling pathway"	--
ENSG00000162408	1.528	1.817	1.507	1.404	1.352	1.65	210	251	153	143	157	165	NOL9	nucleolar protein 9 [Source:HGNC Symbol;Acc:HGNC:26265]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0045111//intermediate filament cytoskeleton	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051731//polynucleotide 5'-hydroxyl-kinase activity	"GO:0000448//cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0016310//phosphorylation"	--
ENSG00000162409	3.443	2.374	2.547	2.609	2.916	3.393	668	463	365	375	478	479	PRKAA2	protein kinase AMP-activated catalytic subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:9377]	Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Signal transduction;Endocrine system;Transport and catabolism;Endocrine and metabolic disease;Endocrine system;Signal transduction;Cardiovascular disease;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04151//PI3K-Akt signaling pathway;ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198;K07198	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:0031588//nucleotide-activated protein kinase complex;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035174//histone serine kinase activity;GO:0046872//metal ion binding;GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0106310//protein serine kinase activity	GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008610//lipid biosynthetic process;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0010629//negative regulation of gene expression;GO:0014850//response to muscle activity;GO:0016055//Wnt signaling pathway;GO:0016126//sterol biosynthetic process;GO:0016239//positive regulation of macroautophagy;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0031669//cellular response to nutrient levels;GO:0032007//negative regulation of TOR signaling;GO:0034599//cellular response to oxidative stress;GO:0035404//histone-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0045821//positive regulation of glycolytic process;GO:0048511//rhythmic process;GO:0055089//fatty acid homeostasis;GO:0062028//regulation of stress granule assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071277//cellular response to calcium ion;GO:0071333//cellular response to glucose stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0097009//energy homeostasis;GO:1903829//positive regulation of cellular protein localization;GO:1904428//negative regulation of tubulin deacetylation;GO:1905691//lipid droplet disassembly;GO:1990044//protein localization to lipid droplet;GO:2000758//positive regulation of peptidyl-lysine acetylation	--
ENSG00000162413	28.405	28.348	29.362	29.143	29.214	30.534	2721	2824	2083	2120	2362	2076	KLHL21	kelch like family member 21 [Source:HGNC Symbol;Acc:HGNC:29041]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005827//polar microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0032465//regulation of cytokinesis;GO:0035853//chromosome passenger complex localization to spindle midzone;GO:0051301//cell division	--
ENSG00000162415	2.588	2.902	2.703	2.595	2.723	2.699	315	355	243	234	280	239	ZSWIM5	zinc finger SWIM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:29299]	-	-	-	-	GO:0005615//extracellular space;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000162419	3.292	3.248	3.778	3.066	2.848	3.11	208	226	168	142	152	149	GMEB1	glucocorticoid modulatory element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4370]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051008//Hsp27 protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	SAND
ENSG00000162426	1.932	1.749	2.536	2.637	2.289	1.916	100	91	95	99	98	72	SLC45A1	solute carrier family 45 member 1 [Source:HGNC Symbol;Acc:HGNC:17939]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008506//sucrose:proton symporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0015770//sucrose transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000162430	50.477	57.297	53.354	46.531	52.462	42.757	4316	4862	3356	2988	3769	2707	-	-	-	-	-	-	-	-	-	-
ENSG00000162433	19.044	19.996	15.596	14.842	17.927	14.232	1688.72	1585.63	941.57	929.18	1271.52	812.6	AK4	adenylate kinase 4 [Source:HGNC Symbol;Acc:HGNC:363]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0046899//nucleoside triphosphate adenylate kinase activity;GO:0050145//nucleoside monophosphate kinase activity"	GO:0002082//regulation of oxidative phosphorylation;GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006172//ADP biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0016310//phosphorylation;GO:0046033//AMP metabolic process;GO:0046034//ATP metabolic process;GO:0046039//GTP metabolic process;GO:0046940//nucleoside monophosphate phosphorylation;GO:0071456//cellular response to hypoxia;GO:2001169//regulation of ATP biosynthetic process	--
ENSG00000162434	46.92	42.201	43.351	36.186	38.455	45.655	4772	4359	3288	2766	3370	3389	JAK1	Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Cellular community - eukaryotes;Development and regeneration;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer	K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217;K11217	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005131//growth hormone receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031730//CCR5 chemokine receptor binding;GO:0046872//metal ion binding	GO:0006468//protein phosphorylation;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0035556//intracellular signal transduction;GO:0038110//interleukin-2-mediated signaling pathway;GO:0038196//type III interferon signaling pathway;GO:0046677//response to antibiotic;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0070102//interleukin-6-mediated signaling pathway;GO:0098586//cellular response to virus;GO:0150105//protein localization to cell-cell junction;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000162437	5.116	5.003	5.117	3.904	4.699	5.35	464	456	343	262	359	351	RAVER2	"ribonucleoprotein, PTB binding 2 [Source:HGNC Symbol;Acc:HGNC:25577]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome"	--
ENSG00000162438	0	0	0	0	0	0	0	0	0	0	0	0	CTRC	chymotrypsin C [Source:HGNC Symbol;Acc:HGNC:2523]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006874//cellular calcium ion homeostasis;GO:0009235//cobalamin metabolic process	--
ENSG00000162441	15.244	15.974	16.439	13.94	12.528	14.185	764	785	609	510	640	548	LZIC	leucine zipper and CTNNBIP1 domain containing [Source:HGNC Symbol;Acc:HGNC:17497]	-	-	-	-	-	GO:0005515//protein binding;GO:0008013//beta-catenin binding	-	--
ENSG00000162444	2.854	2.993	2.402	7.186	3.835	4.029	37	39	23	69	42	38	RBP7	retinol binding protein 7 [Source:HGNC Symbol;Acc:HGNC:30316]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding	GO:0015908//fatty acid transport	--
ENSG00000162456	0	0	0	0	0	0	0	0	0	0	0	0	KNCN	kinocilin [Source:HGNC Symbol;Acc:HGNC:26488]	-	-	-	-	GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032437//cuticular plate;GO:0036064//ciliary basal body;GO:0043025//neuronal cell body;GO:0045177//apical part of cell;GO:0060091//kinocilium	-	-	--
ENSG00000162458	16.64	20.117	15.099	14.279	16.543	15.608	935	991	588	544	731	586	FBLIM1	filamin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:24686]	-	-	-	-	GO:0001650//fibrillar center;GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0071944//cell periphery	GO:0005515//protein binding;GO:0031005//filamin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0008360//regulation of cell shape;GO:0033623//regulation of integrin activation;GO:0098609//cell-cell adhesion	--
ENSG00000162460	0	0	0	0	0	0	0	0	0	0	0	0	TMEM82	transmembrane protein 82 [Source:HGNC Symbol;Acc:HGNC:32350]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000162461	0.277	0.261	0.292	0.333	0.529	0.551	18	17	14	16	29	26	SLC25A34	solute carrier family 25 member 34 [Source:HGNC Symbol;Acc:HGNC:27653]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0001835//blastocyst hatching	--
ENSG00000162482	0.357	1.145	0.054	0.375	0.329	0.164	9	29	1	7	7	3	AKR7A3	aldo-keto reductase family 7 member A3 [Source:HGNC Symbol;Acc:HGNC:390]	Metabolism	Xenobiotics biodegradation and metabolism	ko00980//Metabolism of xenobiotics by cytochrome P450	K15303	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004033//aldo-keto reductase (NADP) activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding	GO:0006081//cellular aldehyde metabolic process;GO:0022900//electron transport chain;GO:0046222//aflatoxin metabolic process;GO:0046223//aflatoxin catabolic process	--
ENSG00000162490	0.033	0	0	0.018	0.008	0.018	5	0	0	2	1	2	DRAXIN	dorsal inhibitory axon guidance protein [Source:HGNC Symbol;Acc:HGNC:25054]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0007411//axon guidance;GO:0010977//negative regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0021516//dorsal spinal cord development;GO:0021528//commissural neuron differentiation in spinal cord;GO:0021960//anterior commissure morphogenesis;GO:0030517//negative regulation of axon extension;GO:0030900//forebrain development;GO:0043524//negative regulation of neuron apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000162493	237.197	247.529	260.587	268.75	274.653	267.494	10921	11343	8913	9096	10387	8784	PDPN	podoplanin [Source:HGNC Symbol;Acc:HGNC:29602]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0031258//lamellipodium membrane;GO:0031410//cytoplasmic vesicle;GO:0031527//filopodium membrane;GO:0031528//microvillus membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0061851//leading edge of lamellipodium;GO:0097197//tetraspanin-enriched microdomain	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019956//chemokine binding;GO:0051087//chaperone binding	"GO:0000902//cell morphogenesis;GO:0001946//lymphangiogenesis;GO:0007266//Rho protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0030168//platelet activation;GO:0030324//lung development;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0044319//wound healing, spreading of cells;GO:0048535//lymph node development;GO:0051272//positive regulation of cellular component movement;GO:0055093//response to hyperoxia;GO:0060838//lymphatic endothelial cell fate commitment;GO:0070252//actin-mediated cell contraction;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0098609//cell-cell adhesion;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:1901731//positive regulation of platelet aggregation;GO:1904328//regulation of myofibroblast contraction;GO:2000392//regulation of lamellipodium morphogenesis"	--
ENSG00000162494	0	0	0	0	0	0	0	0	0	0	0	0	LRRC38	leucine rich repeat containing 38 [Source:HGNC Symbol;Acc:HGNC:27005]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0099104//potassium channel activator activity	GO:0006811//ion transport;GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000162496	124.024	134.422	129.744	131.438	130.513	127.484	5485	6095	4218	4349	4924	4154	DHRS3	dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11146;K11146	GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane	"GO:0000166//nucleotide binding;GO:0004745//NAD-retinol dehydrogenase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650//NADP-retinol dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0003151//outflow tract morphogenesis;GO:0006629//lipid metabolic process;GO:0007601//visual perception;GO:0022900//electron transport chain;GO:0030278//regulation of ossification;GO:0042572//retinol metabolic process;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0060021//roof of mouth development;GO:0060349//bone morphogenesis;GO:0060411//cardiac septum morphogenesis	--
ENSG00000162510	0.025	0.05	0.017	0	0.03	0	2	4	1	0	2	0	MATN1	matrilin 1 [Source:HGNC Symbol;Acc:HGNC:6907]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0120216//matrilin complex	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0002062//chondrocyte differentiation;GO:0003429//growth plate cartilage chondrocyte morphogenesis;GO:0030198//extracellular matrix organization;GO:0030500//regulation of bone mineralization;GO:0065003//protein-containing complex assembly	--
ENSG00000162511	0	0	0	0.03	0.393	0	0	0	0	1	15	0	LAPTM5	lysosomal protein transmembrane 5 [Source:HGNC Symbol;Acc:HGNC:29612]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12387	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0140036//ubiquitin-dependent protein binding;GO:0140311//protein sequestering activity	GO:0002357//defense response to tumor cell;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0006622//protein targeting to lysosome;GO:0006886//intracellular protein transport;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0012502//induction of programmed cell death;GO:0031398//positive regulation of protein ubiquitination;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0032735//positive regulation of interleukin-12 production;GO:0043410//positive regulation of MAPK cascade;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0050869//negative regulation of B cell activation;GO:0060907//positive regulation of macrophage cytokine production;GO:0090160//Golgi to lysosome transport;GO:0097214//positive regulation of lysosomal membrane permeability;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1904093//negative regulation of autophagic cell death;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000646//positive regulation of receptor catabolic process	--
ENSG00000162512	15.501	15.712	16.768	19.536	19.01	17.273	1689	1726	1349	1579	1755	1372	SDC3	syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K16337	GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0044393//microspike;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0016477//cell migration	--
ENSG00000162517	34.949	38.425	41.819	45.609	41.048	47.992	1170	1293	1034	1131	1161	1169	PEF1	penta-EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30009]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0048306//calcium-dependent protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0014029//neural crest formation;GO:0014032//neural crest cell development;GO:0016567//protein ubiquitination;GO:0048208//COPII vesicle coating;GO:0051592//response to calcium ion;GO:1902527//positive regulation of protein monoubiquitination	--
ENSG00000162520	3.429	3.219	2.666	1.654	2.166	3.028	249.13	230.66	91.63	89	132.95	160.06	SYNC	"syncoilin, intermediate filament protein [Source:HGNC Symbol;Acc:HGNC:28897]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0030018//Z disc;GO:0031594//neuromuscular junction;GO:0042383//sarcolemma;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0045103//intermediate filament-based process	--
ENSG00000162521	70.837	69.661	74.637	60.503	62.878	65.718	3213.87	3139.34	2528.37	2031	2350.05	2255.94	RBBP4	"RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887]"	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K10752	"GO:0000118//histone deacetylase complex;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0016581//NuRD complex;GO:0016589//NURF complex;GO:0032991//protein-containing complex;GO:0033186//CAF-1 complex;GO:0035098//ESC/E(Z) complex;GO:1904949//ATPase complex"	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0031492//nucleosomal DNA binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006325//chromatin organization;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0016575//histone deacetylation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031497//chromatin assembly;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000162522	18.373	17.858	19.729	21.613	20.482	23.767	2048	2005	1629	1780	1943	1933	KIAA1522	KIAA1522 [Source:HGNC Symbol;Acc:HGNC:29301]	-	-	-	-	-	-	GO:0030154//cell differentiation	--
ENSG00000162526	0.376	0.187	0.509	0.381	0.556	0.452	8	4	8	6	10	7	TSSK3	testis specific serine kinase 3 [Source:HGNC Symbol;Acc:HGNC:15473]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction	--
ENSG00000162542	3.977	4.049	4.07	3.978	4.788	4.438	240	247	179	177	244	192	TMCO4	transmembrane and coiled-coil domains 4 [Source:HGNC Symbol;Acc:HGNC:27393]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000162543	1.508	1.449	1.35	0.854	1.17	1.06	174	168	115	73	114	89	UBXN10	UBX domain protein 10 [Source:HGNC Symbol;Acc:HGNC:26354]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0030030//cell projection organization;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0060271//cilium assembly	--
ENSG00000162545	0.56	0.474	0.589	1.147	0.932	1.139	27	23	21	41	38	40	CAMK2N1	calcium/calmodulin dependent protein kinase II inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:24190]	-	-	-	-	GO:0005575//cellular_component;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004860//protein kinase inhibitor activity;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding	GO:0006469//negative regulation of protein kinase activity;GO:0007616//long-term memory;GO:0050729//positive regulation of inflammatory response	--
ENSG00000162551	0.215	0.045	0.184	0.077	0.08	0.105	10	2	6	3	3	4	ALPL	"alkaline phosphatase, biomineralization associated [Source:HGNC Symbol;Acc:HGNC:438]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis;ko00730//Thiamine metabolism	K01077;K01077;K01077	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0031966//mitochondrial membrane;GO:0065010//extracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004035//alkaline phosphatase activity;GO:0004427//inorganic diphosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0016887//ATP hydrolysis activity;GO:0033883//pyridoxal phosphatase activity;GO:0043262//adenosine-diphosphatase activity;GO:0046872//metal ion binding;GO:0050187//phosphoamidase activity;GO:0052732//phosphoethanolamine phosphatase activity	GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0003006//developmental process involved in reproduction;GO:0010259//multicellular organism aging;GO:0016311//dephosphorylation;GO:0019725//cellular homeostasis;GO:0030282//bone mineralization;GO:0031214//biomineral tissue development;GO:0032496//response to lipopolysaccharide;GO:0033280//response to vitamin D;GO:0034516//response to vitamin B6;GO:0042822//pyridoxal phosphate metabolic process;GO:0046677//response to antibiotic;GO:0051384//response to glucocorticoid;GO:0055062//phosphate ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0071407//cellular response to organic cyclic compound;GO:0071529//cementum mineralization;GO:0110148//biomineralization;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1904383//response to sodium phosphate	--
ENSG00000162552	0.146	0.218	0.181	0.213	0.276	0.217	12	18	11	13	11	13	WNT4	Wnt family member 4 [Source:HGNC Symbol;Acc:HGNC:12783]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Development and regeneration;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04919//Thyroid hormone signaling pathway;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408;K00408	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0003714//transcription corepressor activity;GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity	"GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0001837//epithelial to mesenchymal transition;GO:0001838//embryonic epithelial tube formation;GO:0001889//liver development;GO:0007275//multicellular organism development;GO:0007276//gamete generation;GO:0007548//sex differentiation;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009267//cellular response to starvation;GO:0010629//negative regulation of gene expression;GO:0010894//negative regulation of steroid biosynthetic process;GO:0016055//Wnt signaling pathway;GO:0022407//regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030237//female sex determination;GO:0030325//adrenal gland development;GO:0030336//negative regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033077//T cell differentiation in thymus;GO:0033080//immature T cell proliferation in thymus;GO:0035239//tube morphogenesis;GO:0035567//non-canonical Wnt signaling pathway;GO:0038030//non-canonical Wnt signaling pathway via MAPK cascade;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042445//hormone metabolic process;GO:0043547//positive regulation of GTPase activity;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045836//positive regulation of meiotic nuclear division;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048599//oocyte development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048856//anatomical structure development;GO:0051145//smooth muscle cell differentiation;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0060070//canonical Wnt signaling pathway;GO:0060126//somatotropin secreting cell differentiation;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0060231//mesenchymal to epithelial transition;GO:0060748//tertiary branching involved in mammary gland duct morphogenesis;GO:0060993//kidney morphogenesis;GO:0061045//negative regulation of wound healing;GO:0061180//mammary gland epithelium development;GO:0061184//positive regulation of dermatome development;GO:0061205//paramesonephric duct development;GO:0061369//negative regulation of testicular blood vessel morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072006//nephron development;GO:0072033//renal vesicle formation;GO:0072034//renal vesicle induction;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072164//mesonephric tubule development;GO:0072174//metanephric tubule formation;GO:0072210//metanephric nephron development;GO:0072273//metanephric nephron morphogenesis;GO:2000019//negative regulation of male gonad development;GO:2000066//positive regulation of cortisol biosynthetic process;GO:2000180//negative regulation of androgen biosynthetic process;GO:2000225//negative regulation of testosterone biosynthetic process;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000162571	0.046	0.162	0	0	0.027	0	2	3	0	0	1	0	TTLL10	tubulin tyrosine ligase like 10 [Source:HGNC Symbol;Acc:HGNC:26693]	-	-	-	-	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0070735//protein-glycine ligase activity	GO:0006464//cellular protein modification process;GO:0018094//protein polyglycylation	--
ENSG00000162572	0.632	0.57	0.497	0.627	0.552	0.562	22	36	19	26	30	23	SCNN1D	sodium channel epithelial 1 subunit delta [Source:HGNC Symbol;Acc:HGNC:10601]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034706//sodium channel complex	GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0008217//regulation of blood pressure;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0036254//cellular response to amiloride;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050914//sensory perception of salty taste;GO:0050915//sensory perception of sour taste;GO:0071468//cellular response to acidic pH;GO:0098719//sodium ion import across plasma membrane;GO:1904045//cellular response to aldosterone;GO:1904117//cellular response to vasopressin	--
ENSG00000162576	11.555	15.409	9.053	8.941	9.532	5.837	549	736	318	315	383	202	MXRA8	matrix remodeling associated 8 [Source:HGNC Symbol;Acc:HGNC:7542]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0060857//establishment of glial blood-brain barrier	--
ENSG00000162585	38.755	38.75	45.15	46.3	42.968	40.793	665.22	669.86	570.99	577.21	624.37	506.97	FAAP20	FA core complex associated protein 20 [Source:HGNC Symbol;Acc:HGNC:26428]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0043240//Fanconi anaemia nuclear complex	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0140036//ubiquitin-dependent protein binding	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0019985//translesion synthesis;GO:0036297//interstrand cross-link repair	--
ENSG00000162591	8.931	8.753	5.043	8.65	8.854	10.283	1099	1030	464	776	955	753	MEGF6	multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000162592	0	0	0	0	0	0	0	0	0	0	0	0	CCDC27	coiled-coil domain containing 27 [Source:HGNC Symbol;Acc:HGNC:26546]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162594	0	0	0	0	0	0	0	0	0	0	0	0	IL23R	interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Immune system;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04659//Th17 cell differentiation;ko05321//Inflammatory bowel disease	K05065;K05065;K05065;K05065;K05065	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0072536//interleukin-23 receptor complex	GO:0004896//cytokine receptor activity;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0042019//interleukin-23 binding;GO:0042020//interleukin-23 receptor activity	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006954//inflammatory response;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032693//negative regulation of interleukin-10 production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032735//positive regulation of interleukin-12 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0034341//response to interferon-gamma;GO:0038155//interleukin-23-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043382//positive regulation of memory T cell differentiation;GO:0045087//innate immune response;GO:0045672//positive regulation of osteoclast differentiation;GO:0050829//defense response to Gram-negative bacterium;GO:0051135//positive regulation of NK T cell activation;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000330//positive regulation of T-helper 17 cell lineage commitment	--
ENSG00000162595	0.604	1.051	0.501	0.264	0.586	0.345	24	36	13	6	16	9	DIRAS3	DIRAS family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:687]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006349//regulation of gene expression by genetic imprinting;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction	--
ENSG00000162598	0.309	0.213	0.032	0	0.028	0.033	10	9	1	0	1	1	C1orf87	chromosome 1 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:28547]	-	-	-	-	-	-	-	--
ENSG00000162599	3.271	2.937	2.918	2.388	2.379	1.823	329	286	209	130	186	156	NFIA	nuclear factor I A [Source:HGNC Symbol;Acc:HGNC:7784]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019079//viral genome replication;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060074//synapse maturation;GO:0072189//ureter development"	CTF/NFI
ENSG00000162600	8.736	6.801	7.135	8.23	7.12	7.598	237	226	183	188	198	189	OMA1	OMA1 zinc metallopeptidase [Source:HGNC Symbol;Acc:HGNC:29661]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K23010	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0002024//diet induced thermogenesis;GO:0006006//glucose metabolic process;GO:0006508//proteolysis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0006629//lipid metabolic process;GO:0007005//mitochondrion organization;GO:0010637//negative regulation of mitochondrial fusion;GO:0016540//protein autoprocessing;GO:0031638//zymogen activation;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0034982//mitochondrial protein processing;GO:0042407//cristae formation;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0097009//energy homeostasis;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0140467//integrated stress response signaling;GO:0140468//HRI-mediated signaling;GO:1903850//regulation of cristae formation	--
ENSG00000162601	2.009	1.757	1.801	1.496	1.713	2.15	286	246	191	168	206	216	MYSM1	"Myb like, SWIRM and MPN domains 1 [Source:HGNC Symbol;Acc:HGNC:29401]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0002376//immune system process;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006508//proteolysis;GO:0030334//regulation of cell migration;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043473//pigmentation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051797//regulation of hair follicle development;GO:1903706//regulation of hemopoiesis	MYB
ENSG00000162604	17.808	17.989	18.904	18.529	17.338	22.626	362	364	280	273	294	328	TM2D1	TM2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24142]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001540//amyloid-beta binding;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0097190//apoptotic signaling pathway	--
ENSG00000162607	8.74	6.458	6.372	4.61	4.832	4.879	653	485	351	254	305	264	USP1	ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K11832	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001501//skeletal system development;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0016579//protein deubiquitination;GO:0035520//monoubiquitinated protein deubiquitination	--
ENSG00000162613	46.935	45.782	44.605	39.151	40.711	54.843	2833	2630	1906	1708	1987	2286	FUBP1	far upstream element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4004]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0110165//cellular anatomical entity	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression"	--
ENSG00000162614	2.506	2.779	1.396	1.06	1.568	1.231	144	130	52	38	68	56	NEXN	nexilin F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:29557]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0030424//axon	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0051015//actin filament binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0030334//regulation of cell migration;GO:0051493//regulation of cytoskeleton organization;GO:0070593//dendrite self-avoidance	--
ENSG00000162616	8.902	7.567	8.162	7.399	7.253	7.441	536	458	363	330	369	326	DNAJB4	DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0009408//response to heat;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000162618	0.168	0.042	0	0.096	0.166	0	2	2	0	4	4	0	ADGRL4	adhesion G protein-coupled receptor L4 [Source:HGNC Symbol;Acc:HGNC:20822]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0065003//protein-containing complex assembly	--
ENSG00000162620	0.091	0.151	0	0	0.036	0.042	3	5	0	0	1	1	LRRIQ3	leucine rich repeats and IQ motif containing 3 [Source:HGNC Symbol;Acc:HGNC:28318]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162621	0	0	0	0	0	0	0	0	0	0	0	0	LRRC53	leucine rich repeat containing 53 [Source:HGNC Symbol;Acc:HGNC:25255]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000162623	7.677	7.171	8.098	5.534	6.004	6.66	404.95	348.93	296.56	219	301.87	261.7	TYW3	tRNA-yW synthesizing protein 3 homolog [Source:HGNC Symbol;Acc:HGNC:24757]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016740//transferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000162624	0	0	0	0	0	0	0	0	0	0	0	0	LHX8	LIM homeobox 8 [Source:HGNC Symbol;Acc:HGNC:28838]	-	-	-	-	GO:0000785//chromatin;GO:0001674//female germ cell nucleus;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007611//learning or memory;GO:0008585//female gonad development;GO:0021879//forebrain neuron differentiation;GO:0021884//forebrain neuron development;GO:0030182//neuron differentiation;GO:0042475//odontogenesis of dentin-containing tooth"	Homeobox
ENSG00000162627	9.338	7.036	7.038	7.19	6.574	7.819	334	252	186	190	199	202	SNX7	sorting nexin 7 [Source:HGNC Symbol;Acc:HGNC:14971]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding	GO:0015031//protein transport;GO:0016197//endosomal transport;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000162630	0.611	0.527	0.184	0.294	0.386	0.43	45	39	10	16	24	23	B3GALT2	"beta-1,3-galactosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:917]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07820;K07820	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047275//glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006682//galactosylceramide biosynthetic process;GO:0009312//oligosaccharide biosynthetic process	--
ENSG00000162631	3.29	2.738	2.115	2.292	2.843	2	199	176	101	108	128	82	NTNG1	netrin G1 [Source:HGNC Symbol;Acc:HGNC:23319]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction	ko04360//Axon guidance;ko04514//Cell adhesion molecules	K07522;K07522	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043256//laminin complex;GO:0046658//anchored component of plasma membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099029//anchored component of presynaptic active zone membrane	GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0010975//regulation of neuron projection development;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050804//modulation of chemical synaptic transmission;GO:0070831//basement membrane assembly;GO:0099560//synaptic membrane adhesion;GO:0150011//regulation of neuron projection arborization;GO:2001222//regulation of neuron migration	--
ENSG00000162636	2.236	1.881	2.175	2.273	2.044	2.16	259	219	174	195	200	182	FAM102B	family with sequence similarity 102 member B [Source:HGNC Symbol;Acc:HGNC:27637]	-	-	-	-	-	-	-	--
ENSG00000162639	2.131	2.869	2.36	2.762	2.619	2.243	77	104	63	77	86	63	HENMT1	HEN methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26400]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043186//P granule	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0090486//small RNA 2'-O-methyltransferase	GO:0001510//RNA methylation;GO:0030422//production of siRNA involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0032259//methylation;GO:0034587//piRNA metabolic process	--
ENSG00000162641	0	0	0	0	0	0	0	0	0	0	0	0	AKNAD1	AKNA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28398]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162642	8.133	4.761	6.78	10.023	5.395	8.48	233	187	187	201	175	176	C1orf52	chromosome 1 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:24871]	-	-	-	-	GO:0005654//nucleoplasm	GO:0003723//RNA binding	-	--
ENSG00000162643	1.011	1.072	0.415	0.318	0.575	0.579	62	53	18	9	13	26	DNAI3	dynein axonemal intermediate chain 3 [Source:HGNC Symbol;Acc:HGNC:30711]	-	-	-	-	GO:0005737//cytoplasm;GO:0005858//axonemal dynein complex;GO:0036156//inner dynein arm	GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding;GO:0071933//Arp2/3 complex binding	GO:0007018//microtubule-based movement;GO:0030336//negative regulation of cell migration;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0036159//inner dynein arm assembly;GO:0045669//positive regulation of osteoblast differentiation;GO:0060294//cilium movement involved in cell motility	--
ENSG00000162645	0.276	0.364	0.414	0.459	0.586	0.361	22	31	24	26	42	21	GBP2	guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20897	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006955//immune response;GO:0034504//protein localization to nucleus;GO:0042832//defense response to protozoan;GO:0050830//defense response to Gram-positive bacterium;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000162650	1.941	1.828	2.522	2.061	1.92	1.95	101	94	95	78	84	74	ATXN7L2	ataxin 7 like 2 [Source:HGNC Symbol;Acc:HGNC:28713]	-	-	-	-	-	-	-	--
ENSG00000162654	0.29	0.273	0.276	0.413	0.335	0.334	37	35	26	39	36	31	GBP4	guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20899	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0042832//defense response to protozoan;GO:0050830//defense response to Gram-positive bacterium;GO:0071346//cellular response to interferon-gamma	--
ENSG00000162664	14.827	12.432	11.266	9.388	12.415	13.819	1011	817	556	495	696	695	ZNF326	zinc finger protein 326 [Source:HGNC Symbol;Acc:HGNC:14104]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0044609//DBIRD complex	GO:0000993//RNA polymerase II complex binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0043484//regulation of RNA splicing"	Others
ENSG00000162669	0.069	0.198	0.08	0.195	0.318	0.081	7	5	6	5	9	6	HFM1	helicase for meiosis 1 [Source:HGNC Symbol;Acc:HGNC:20193]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0032508//DNA duplex unwinding;GO:0051321//meiotic cell cycle	--
ENSG00000162670	0	0	0	0	0	0	0	0	0	0	0	0	BRINP3	BMP/retinoic acid inducible neural specific 3 [Source:HGNC Symbol;Acc:HGNC:22393]	-	-	-	-	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0030425//dendrite;GO:0043025//neuronal cell body	-	GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0045666//positive regulation of neuron differentiation;GO:0045786//negative regulation of cell cycle;GO:0045930//negative regulation of mitotic cell cycle;GO:0071300//cellular response to retinoic acid	--
ENSG00000162676	0	0	0.014	0	0	0.024	0	0	1	0	0	1	GFI1	growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237]	-	-	-	-	GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0017053//transcription repressor complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0010977//negative regulation of neuron projection development;GO:0016032//viral process;GO:0030097//hemopoiesis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051569//regulation of histone H3-K4 methylation;GO:0070105//positive regulation of interleukin-6-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide"	zf-C2H2
ENSG00000162687	1.763	0.905	0.824	0.454	0.663	1.059	184	102	67	41	69	79	KCNT2	potassium sodium-activated channel subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:18866]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005228//intracellular sodium activated potassium channel activity;GO:0005267//potassium channel activity;GO:0005524//ATP binding;GO:0015271//outward rectifier potassium channel activity;GO:0022839//ion gated channel activity;GO:0070089//chloride-activated potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0097623//potassium ion export across plasma membrane	--
ENSG00000162688	5.648	3.707	3.857	2.855	3.404	3.971	831	548	419	311	423	425	AGL	"amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase [Source:HGNC Symbol;Acc:HGNC:321]"	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K01196;K01196	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016234//inclusion body;GO:0016529//sarcoplasmic reticulum;GO:0034774//secretory granule lumen;GO:0043033//isoamylase complex;GO:1904813//ficolin-1-rich granule lumen	"GO:0003824//catalytic activity;GO:0004133//glycogen debranching enzyme activity;GO:0004134//4-alpha-glucanotransferase activity;GO:0004135//amylo-alpha-1,6-glucosidase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0102500//beta-maltose 4-alpha-glucanotransferase activity"	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0005980//glycogen catabolic process;GO:0007584//response to nutrient;GO:0008152//metabolic process;GO:0009725//response to hormone;GO:0051384//response to glucocorticoid	--
ENSG00000162692	0.609	0.294	0.267	0.327	0.287	0.071	33	19	11	15	15	3	VCAM1	vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Signal transduction;Signaling molecules and interaction;Cardiovascular disease;Immune system;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic	ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04670//Leukocyte transendothelial migration;ko04668//TNF signaling pathway;ko05143//African trypanosomiasis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05144//Malaria	K06527;K06527;K06527;K06527;K06527;K06527;K06527;K06527;K06527	GO:0002102//podosome;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030175//filopodium;GO:0042383//sarcolemma;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0071065//alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	GO:0005178//integrin binding;GO:0008131//primary amine oxidase activity;GO:0050839//cell adhesion molecule binding	GO:0001666//response to hypoxia;GO:0002526//acute inflammatory response;GO:0002544//chronic inflammatory response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007568//aging;GO:0007584//response to nutrient;GO:0009308//amine metabolic process;GO:0010043//response to zinc ion;GO:0010212//response to ionizing radiation;GO:0022614//membrane to membrane docking;GO:0030183//B cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0034113//heterotypic cell-cell adhesion;GO:0035094//response to nicotine;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042102//positive regulation of T cell proliferation;GO:0045471//response to ethanol;GO:0050901//leukocyte tethering or rolling;GO:0060326//cell chemotaxis;GO:0060384//innervation;GO:0060945//cardiac neuron differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:0098609//cell-cell adhesion;GO:0140039//cell-cell adhesion in response to extracellular stimulus;GO:1904646//cellular response to amyloid-beta	--
ENSG00000162694	8.749	7.915	7.892	6.805	7.187	7.31	515	469	343	297	360	304	EXTL2	exostosin like glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3516]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02369;K02369	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0035248//alpha-1,4-N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity"	GO:0006044//N-acetylglucosamine metabolic process;GO:0006486//protein glycosylation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process	--
ENSG00000162695	4.933	4.757	4.685	3.113	3.765	4.384	818	789	572	381	530	531	SLC30A7	solute carrier family 30 member 7 [Source:HGNC Symbol;Acc:HGNC:19306]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0005385//zinc ion transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0032119//sequestering of zinc ion;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000162702	6.128	5.037	4.317	4.02	5.317	5.103	557	445	298	275	386	335	ZNF281	zinc finger protein 281 [Source:HGNC Symbol;Acc:HGNC:13075]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0010172//embryonic body morphogenesis;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048863//stem cell differentiation"	zf-C2H2
ENSG00000162704	83.435	74.886	81.213	89.247	71.214	77.307	3466	3275	2589	2708	2709	2529	ARPC5	actin related protein 2/3 complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:708]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05754;K05754;K05754;K05754;K05754;K05754;K05754;K05754;K05754	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0034774//secretory granule lumen;GO:0035861//site of double-strand break;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0014909//smooth muscle cell migration;GO:0016477//cell migration;GO:0021769//orbitofrontal cortex development;GO:0030011//maintenance of cell polarity;GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0051639//actin filament network formation;GO:0061842//microtubule organizing center localization;GO:0097581//lamellipodium organization	--
ENSG00000162706	2.3	1.797	0.908	2.401	2.387	1.678	143	131	52	114	128	87	CADM3	cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17601]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06780	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000162711	0.053	0	0.026	0.018	0	0	4	0	1	1	0	0	NLRP3	NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: bacterial;Immune system;Infectious disease: viral;Cell growth and death;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko04625//C-type lectin receptor signaling pathway;ko05133//Pertussis	K12800;K12800;K12800;K12800;K12800;K12800;K12800;K12800;K12800;K12800;K12800	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0061702//inflammasome complex;GO:0072559//NLRP3 inflammasome complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042834//peptidoglycan binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0002526//acute inflammatory response;GO:0002674//negative regulation of acute inflammatory response;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002830//positive regulation of type 2 immune response;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007231//osmosensory signaling pathway;GO:0009595//detection of biotic stimulus;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044546//NLRP3 inflammasome complex assembly;GO:0045087//innate immune response;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0070269//pyroptosis;GO:0071222//cellular response to lipopolysaccharide;GO:0071224//cellular response to peptidoglycan;GO:0098586//cellular response to virus;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:2000321//positive regulation of T-helper 17 cell differentiation;GO:2000553//positive regulation of T-helper 2 cell cytokine production	--
ENSG00000162714	9.953	9.527	9.561	10.277	10.014	10.002	1048	990	722	763	845	758	ZNF496	zinc finger protein 496 [Source:HGNC Symbol;Acc:HGNC:23713]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000162722	1.753	1.651	1.49	2.631	2.097	2.794	188	178	118	209	190	218	TRIM58	tripartite motif containing 58 [Source:HGNC Symbol;Acc:HGNC:24150]	-	-	-	-	GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0045504//dynein heavy chain binding;GO:0045505//dynein intermediate chain binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008150//biological_process;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response;GO:0051865//protein autoubiquitination;GO:0061931//positive regulation of erythrocyte enucleation;GO:1902838//regulation of nuclear migration along microtubule	--
ENSG00000162723	0	0	0	0	0	0	0	0	0	0	0	0	SLAMF9	SLAM family member 9 [Source:HGNC Symbol;Acc:HGNC:18430]	-	-	-	-	GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0042110//T cell activation	--
ENSG00000162727	0	0	0	0	0	0	0	0	0	0	0	0	OR2M5	olfactory receptor family 2 subfamily M member 5 [Source:HGNC Symbol;Acc:HGNC:19576]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000162728	0	0	0	0	0	0	0	0	0	0	0	0	KCNJ9	potassium inwardly rectifying channel subfamily J member 9 [Source:HGNC Symbol;Acc:HGNC:6270]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Endocrine system;Nervous system;Endocrine system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Endocrine system	ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04929//GnRH secretion	K05002;K05002;K05002;K05002;K05002;K05002;K05002;K05002	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0099056//integral component of presynaptic membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000162729	10.554	9.899	11.501	11.595	13.253	13.35	500	462	402	386	519	460	IGSF8	immunoglobulin superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:17813]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007338//single fertilization;GO:0007399//nervous system development;GO:0007519//skeletal muscle tissue development;GO:0048870//cell motility	--
ENSG00000162733	34.423	28.367	29.095	22.382	24.686	24.857	5908	4905	3651	2705	3337	2885	DDR2	discoidin domain receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:2731]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038062//protein tyrosine kinase collagen receptor activity	GO:0001503//ossification;GO:0003416//endochondral bone growth;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010715//regulation of extracellular matrix disassembly;GO:0010763//positive regulation of fibroblast migration;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030199//collagen fibril organization;GO:0030500//regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033673//negative regulation of kinase activity;GO:0033674//positive regulation of kinase activity;GO:0034103//regulation of tissue remodeling;GO:0035988//chondrocyte proliferation;GO:0035994//response to muscle stretch;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060547//negative regulation of necrotic cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071456//cellular response to hypoxia;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0090303//positive regulation of wound healing;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1901216//positive regulation of neuron death;GO:1901299//negative regulation of hydrogen peroxide-mediated programmed cell death;GO:1904385//cellular response to angiotensin;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1904899//positive regulation of hepatic stellate cell proliferation;GO:2000491//positive regulation of hepatic stellate cell activation	--
ENSG00000162734	83.168	85.87	74.87	82.459	82.373	79.078	4149	4280	2760	3008	3444	2843	PEA15	proliferation and apoptosis adaptor protein 15 [Source:HGNC Symbol;Acc:HGNC:8822]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005875//microtubule associated complex	GO:0005515//protein binding	GO:0000165//MAPK cascade;GO:0006915//apoptotic process;GO:0008643//carbohydrate transport;GO:0042981//regulation of apoptotic process;GO:0043278//response to morphine;GO:0046325//negative regulation of glucose import;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000162735	29.344	33.203	31.046	24.031	24.257	25.482	1739.88	1800.78	1367	1101.66	1346.2	1217	PEX19	peroxisomal biogenesis factor 19 [Source:HGNC Symbol;Acc:HGNC:9713]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13337	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0033328//peroxisome membrane targeting sequence binding;GO:0036105//peroxisome membrane class-1 targeting sequence binding;GO:0047485//protein N-terminus binding;GO:0051117//ATPase binding;GO:0140597//protein carrier activity	GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0016559//peroxisome fission;GO:0045046//protein import into peroxisome membrane;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:0072663//establishment of protein localization to peroxisome;GO:1900131//negative regulation of lipid binding	--
ENSG00000162736	69.754	73.206	70.983	71.012	75.801	74.643	3810	3944	2889	2801	3456	2909	NCSTN	nicastrin [Source:HGNC Symbol;Acc:HGNC:17091]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05010//Alzheimer disease;ko04330//Notch signaling pathway	K06171;K06171	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0035577//azurophil granule membrane;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0070765//gamma-secretase complex;GO:0097060//synaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0110165//cellular anatomical entity	"GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0030674//protein-macromolecule adaptor activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0051117//ATPase binding;GO:0070851//growth factor receptor binding"	GO:0002262//myeloid cell homeostasis;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0007212//dopamine receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0007611//learning or memory;GO:0010950//positive regulation of endopeptidase activity;GO:0016485//protein processing;GO:0021549//cerebellum development;GO:0022010//central nervous system myelination;GO:0030534//adult behavior;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034205//amyloid-beta formation;GO:0042098//T cell proliferation;GO:0042982//amyloid precursor protein metabolic process;GO:0042983//amyloid precursor protein biosynthetic process;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0050435//amyloid-beta metabolic process;GO:0050673//epithelial cell proliferation;GO:0051402//neuron apoptotic process;GO:0070997//neuron death;GO:0071277//cellular response to calcium ion;GO:1900271//regulation of long-term synaptic potentiation;GO:1990926//short-term synaptic potentiation	--
ENSG00000162738	11.904	11.252	11.68	11.135	11.255	13.18	1322	1256	958	916	1056	1065	VANGL2	VANGL planar cell polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:15511]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04510	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane	GO:0005515//protein binding	"GO:0001736//establishment of planar polarity;GO:0001843//neural tube closure;GO:0001947//heart looping;GO:0007275//multicellular organism development;GO:0035787//cell migration involved in kidney development;GO:0045176//apical protein localization;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:1905515//non-motile cilium assembly"	--
ENSG00000162739	0	0	0	0	0.042	0	0	0	0	0	2	0	SLAMF6	SLAM family member 6 [Source:HGNC Symbol;Acc:HGNC:21392]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0042110//T cell activation;GO:0045087//innate immune response;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0072540//T-helper 17 cell lineage commitment	--
ENSG00000162745	2.028	2.308	0.679	0.082	0.83	0.23	113	148	31	4	28	11	OLFML2B	olfactomedin like 2B [Source:HGNC Symbol;Acc:HGNC:24558]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0042802//identical protein binding;GO:0050840//extracellular matrix binding	GO:0007165//signal transduction;GO:0030198//extracellular matrix organization	--
ENSG00000162746	0.268	0.461	0.269	0.263	0.548	0.335	11	19	8	8	19	10	FCRLB	Fc receptor like B [Source:HGNC Symbol;Acc:HGNC:26431]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane	GO:0004888//transmembrane signaling receptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0050777//negative regulation of immune response	--
ENSG00000162747	0	0	0	0	0	0	0	0	0	0	0	0	FCGR3B	Fc fragment of IgG receptor IIIb [Source:HGNC Symbol;Acc:HGNC:3620]	Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Transport and catabolism;Immune disease;Immune system;Immune system;Infectious disease: bacterial;Infectious disease: parasitic;Development and regeneration	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko04650//Natural killer cell mediated cytotoxicity;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation	K06463;K06463;K06463;K06463;K06463;K06463;K06463;K06463;K06463	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0019864//IgG binding;GO:0034235//GPI anchor binding	GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response	--
ENSG00000162753	0	0.011	0	0	0	0	0	1	0	0	0	0	SLC9C2	solute carrier family 9 member C2 (putative) [Source:HGNC Symbol;Acc:HGNC:28664]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000162755	3.006	2.215	3.542	3.189	2.59	3.255	84	62	73	66	61	66	KLHDC9	kelch domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28489]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0030332//cyclin binding	GO:0008150//biological_process	--
ENSG00000162757	0.869	0.734	0.777	0.844	0.606	0.749	84.46	71.65	55.76	60.77	49.74	52.95	C1orf74	chromosome 1 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:26319]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162761	0.029	0.084	0.147	0.058	0.18	0.113	2	5	8	3	11	4	LMX1A	LIM homeobox transcription factor 1 alpha [Source:HGNC Symbol;Acc:HGNC:6653]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001558//regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0010468//regulation of gene expression;GO:0021542//dentate gyrus development;GO:0021549//cerebellum development;GO:0021766//hippocampus development;GO:0021953//central nervous system neuron differentiation;GO:0030182//neuron differentiation;GO:0030901//midbrain development;GO:0042048//olfactory behavior;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050808//synapse organization;GO:0071542//dopaminergic neuron differentiation;GO:1904948//midbrain dopaminergic neuron differentiation"	Homeobox
ENSG00000162763	0	0	0	0	0	0	0	0	0	0	0	0	LRRC52	leucine rich repeat containing 52 [Source:HGNC Symbol;Acc:HGNC:32156]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0099104//potassium channel activator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0022414//reproductive process;GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000162769	2.427	2.083	2.029	2.334	2.573	3.144	298	257	184	178	203	204	FLVCR1	FLVCR heme transporter 1 [Source:HGNC Symbol;Acc:HGNC:24682]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0015232//heme transmembrane transporter activity;GO:0020037//heme binding;GO:0022857//transmembrane transporter activity	GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0006783//heme biosynthetic process;GO:0006839//mitochondrial transport;GO:0006879//cellular iron ion homeostasis;GO:0015886//heme transport;GO:0030218//erythrocyte differentiation;GO:0035108//limb morphogenesis;GO:0035264//multicellular organism growth;GO:0042733//embryonic digit morphogenesis;GO:0043249//erythrocyte maturation;GO:0046620//regulation of organ growth;GO:0048536//spleen development;GO:0048704//embryonic skeletal system morphogenesis;GO:0055085//transmembrane transport;GO:0060323//head morphogenesis;GO:0097037//heme export	--
ENSG00000162771	0	0	0	0	0	0	0	0	0	0	0	0	FAM71A	family with sequence similarity 71 member A [Source:HGNC Symbol;Acc:HGNC:26541]	-	-	-	-	GO:0005634//nucleus;GO:0005794//Golgi apparatus	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000162772	0.257	0.558	0.236	0.636	0.029	0.557	6	8	7	6	1	11	ATF3	activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990622//CHOP-ATF3 complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006094//gluconeogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034198//cellular response to amino acid starvation;GO:0035914//skeletal muscle cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061394//regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	TF_bZIP
ENSG00000162775	2.148	2.606	2.945	2.375	2.21	2.872	147	177	149	120	128	141	RBM15	RNA binding motif protein 15 [Source:HGNC Symbol;Acc:HGNC:14959]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001510//RNA methylation;GO:0001569//branching involved in blood vessel morphogenesis;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045652//regulation of megakaryocyte differentiation;GO:0048536//spleen development;GO:0060412//ventricular septum morphogenesis;GO:0060674//placenta blood vessel development"	--
ENSG00000162777	2.219	2.323	2.132	2.326	2.301	2.359	105	99	65	71	81	76	DENND2D	DENN domain containing 2D [Source:HGNC Symbol;Acc:HGNC:26192]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000162779	0	0.014	0.092	0.023	0	0.07	0	1	4	1	0	3	AXDND1	axonemal dynein light chain domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26564]	-	-	-	-	-	-	-	--
ENSG00000162782	0.083	0.027	0	0.113	0	0	4	1	0	5	0	0	TDRD5	tudor domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20614]	-	-	-	-	GO:0005737//cytoplasm;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0071546//pi-body	-	GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation	--
ENSG00000162783	1.171	0.993	0.963	1.379	1.195	1.467	102	87	62	89	88	93	IER5	immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393]	-	-	-	-	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0034605//cellular response to heat;GO:0042127//regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1900036//positive regulation of cellular response to heat	--
ENSG00000162804	3.324	3.727	3.635	2.615	4.065	5.03	356.37	390.43	323.5	318.49	340.24	354.28	SNED1	"sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696]"	-	-	-	-	GO:0005576//extracellular region	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007160//cell-matrix adhesion	--
ENSG00000162813	13.3	12.547	14.654	12.728	10.324	11.762	384	434	331	266	231	270	BPNT1	"3'(2'), 5'-bisphosphate nucleotidase 1 [Source:HGNC Symbol;Acc:HGNC:1096]"	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K01082;K01082	GO:0005829//cytosol	"GO:0008441//3'(2'),5'-bisphosphate nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006139//nucleobase-containing compound metabolic process;GO:0007399//nervous system development;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0046855//inositol phosphate dephosphorylation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process	--
ENSG00000162814	0.333	0.219	0.124	0.135	0.128	0.218	40	19	11	12	13	17	SPATA17	spermatogenesis associated 17 [Source:HGNC Symbol;Acc:HGNC:25184]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000162817	0.183	0.348	0.226	0.518	0.651	0.206	11	21	10	23	33	9	C1orf115	chromosome 1 open reading frame 115 [Source:HGNC Symbol;Acc:HGNC:25873]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097731//9+0 non-motile cilium	-	-	--
ENSG00000162819	9.795	6.051	10.127	6.659	6.528	8.332	638	508	400	237	364	374	BROX	BRO1 domain and CAAX motif containing [Source:HGNC Symbol;Acc:HGNC:26512]	-	-	-	-	GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000162825	0.554	0.457	0.443	0.29	0.42	0.365	215.74	178.75	127.21	83.51	138	103.36	NBPF20	NBPF member 20 [Source:HGNC Symbol;Acc:HGNC:32000]	-	-	-	-	-	-	-	--
ENSG00000162836	17.145	23.342	26.171	16.481	11.104	24.882	840	862	684	677	670	681	ACP6	"acid phosphatase 6, lysophosphatidic [Source:HGNC Symbol;Acc:HGNC:29609]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003993//acid phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0052642//lysophosphatidic acid phosphatase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016311//dephosphorylation;GO:2001311//lysobisphosphatidic acid metabolic process	--
ENSG00000162843	0	0.021	0	0	0	0	0	1	0	0	0	0	WDR64	WD repeat domain 64 [Source:HGNC Symbol;Acc:HGNC:26570]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162849	7.538	8.705	7.583	7.018	7.808	5.612	2092	2467	1575	1431	1860	1142	KIF26B	kinesin family member 26B [Source:HGNC Symbol;Acc:HGNC:25484]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding	GO:0007018//microtubule-based movement;GO:0022409//positive regulation of cell-cell adhesion;GO:0030010//establishment of cell polarity;GO:0072092//ureteric bud invasion	--
ENSG00000162851	5.027	4.651	4.793	4.779	5.342	5.46	186	173	131	131	167	147	TFB2M	"transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid	"GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0016740//transferase activity;GO:0034246//mitochondrial transcription factor activity"	"GO:0000154//rRNA modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006364//rRNA processing;GO:0006390//mitochondrial transcription;GO:0006391//transcription initiation from mitochondrial promoter;GO:0031167//rRNA methylation;GO:0032259//methylation"	--
ENSG00000162852	8.025	7.753	6.506	5.065	6.547	7.246	771	753	511	399	541	554	CNST	"consortin, connexin sorting protein [Source:HGNC Symbol;Acc:HGNC:26486]"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0071253//connexin binding	GO:0042998//positive regulation of Golgi to plasma membrane protein transport	--
ENSG00000162869	9.508	9.105	8.13	7.282	6.417	6.297	602	579	395	338	357	295	PPP1R21	protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000162873	0.44	0.445	0.67	0.84	1.382	1.664	29	29	31	41	46	48	KLHDC8A	kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162877	0	0	0	0	0	0.031	0	0	0	0	0	1	PM20D1	peptidase M20 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26518]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	"GO:0004046//aminoacylase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016829//lyase activity;GO:0046872//metal ion binding"	GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0043604//amide biosynthetic process;GO:0043605//cellular amide catabolic process;GO:0044255//cellular lipid metabolic process;GO:0097009//energy homeostasis;GO:1901215//negative regulation of neuron death;GO:1990845//adaptive thermogenesis;GO:2000275//regulation of oxidative phosphorylation uncoupler activity	--
ENSG00000162878	1.317	2.235	2.097	2.326	2.177	2.475	68	116	80	89	95	93	PKDCC	"protein kinase domain containing, cytoplasmic [Source:HGNC Symbol;Acc:HGNC:25123]"	-	-	-	-	GO:0005576//extracellular region;GO:0005794//Golgi apparatus	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0006468//protein phosphorylation;GO:0015031//protein transport;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030282//bone mineralization;GO:0030501//positive regulation of bone mineralization;GO:0032332//positive regulation of chondrocyte differentiation;GO:0035108//limb morphogenesis;GO:0035264//multicellular organism growth;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0048286//lung alveolus development;GO:0048566//embryonic digestive tract development;GO:0060021//roof of mouth development	--
ENSG00000162881	0.442	0.234	0.319	0.278	0.488	0.486	15	8	8	7	14	12	OXER1	oxoeicosanoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:24884]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0050646//5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding;GO:0050647//5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding;GO:0050648//5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding"	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	--
ENSG00000162882	3.915	5.652	3.95	3.213	4.543	3.218	102	148	76	62	100	61	HAAO	"3-hydroxyanthranilate 3,4-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4796]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K00452;K00452	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000334//3-hydroxyanthranilate 3,4-dioxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0006569//tryptophan catabolic process;GO:0009435//NAD biosynthetic process;GO:0010043//response to zinc ion;GO:0019363//pyridine nucleotide biosynthetic process;GO:0019805//quinolinate biosynthetic process;GO:0022900//electron transport chain;GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0043420//anthranilate metabolic process;GO:0046686//response to cadmium ion;GO:0046874//quinolinate metabolic process;GO:0070050//neuron cellular homeostasis	--
ENSG00000162885	8.44	7.603	8.878	6.533	8.658	8.454	809.84	716.17	550.7	455.25	655.09	562.56	B3GALNT2	"beta-1,3-N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:28596]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K09654;K09654	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation	--
ENSG00000162889	24.93	26.659	25.767	28.307	27.646	27.639	1579	1691	1208	1327	1483	1263	MAPKAPK2	MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing	Signal transduction;Cancer: overview;Infectious disease: viral;Cell growth and death;Nervous system;Immune system;Signal transduction	ko04010//MAPK signaling pathway;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04370//VEGF signaling pathway	K04443;K04443;K04443;K04443;K04443;K04443;K04443	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002224//toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0006691//leukotriene metabolic process;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032496//response to lipopolysaccharide;GO:0032675//regulation of interleukin-6 production;GO:0032680//regulation of tumor necrosis factor production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034097//response to cytokine;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038066//p38MAPK cascade;GO:0043488//regulation of mRNA stability;GO:0044351//macropinocytosis;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048255//mRNA stabilization;GO:0048839//inner ear development;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:1900034//regulation of cellular response to heat	--
ENSG00000162891	0	0	0	0	0	0	0	0	0	0	0	0	IL20	interleukin 20 [Source:HGNC Symbol;Acc:HGNC:6002]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22667;K22667;K22667	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0045517//interleukin-20 receptor binding;GO:0045518//interleukin-22 receptor binding	GO:0007165//signal transduction;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045606//positive regulation of epidermal cell differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0050727//regulation of inflammatory response	--
ENSG00000162892	0	0	0	0	0.086	0	0	0	0	0	2	0	IL24	interleukin 24 [Source:HGNC Symbol;Acc:HGNC:11346]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22668;K22668;K22668	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0030336//negative regulation of cell migration;GO:0042060//wound healing;GO:0042501//serine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071222//cellular response to lipopolysaccharide;GO:0071353//cellular response to interleukin-4	--
ENSG00000162894	0.201	0	0.104	0.045	0.079	0.266	6	0	4	1	2	5	FCMR	Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity	GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0043066//negative regulation of apoptotic process	--
ENSG00000162896	0.011	0	0	0.015	0	0	1	0	0	1	0	0	PIGR	polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968]	Organismal Systems	Immune system	ko04672//Intestinal immune network for IgA production	K13073	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome;GO:0071751//secretory IgA immunoglobulin complex	GO:0001792//polymeric immunoglobulin receptor activity;GO:0004888//transmembrane signaling receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001895//retina homeostasis;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0038093//Fc receptor signaling pathway;GO:0043113//receptor clustering	--
ENSG00000162897	0	0	0	0	0	0	0	0	0	0	0	0	FCAMR	Fc fragment of IgA and IgM receptor [Source:HGNC Symbol;Acc:HGNC:24692]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000162909	56.21	54.786	48.868	45.149	45.929	48.894	3918	3839	2516	2332	2685	2481	CAPN2	calpain 2 [Source:HGNC Symbol;Acc:HGNC:1479]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Genetic Information Processing;Cellular Processes;Cellular Processes;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Cellular community - eukaryotes;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Cell growth and death"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05131//Shigellosis;ko04510//Focal adhesion;ko04141//Protein processing in endoplasmic reticulum;ko04217//Necroptosis;ko04218//Cellular senescence;ko04210//Apoptosis	K03853;K03853;K03853;K03853;K03853;K03853;K03853;K03853	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0030864//cortical actin cytoskeleton;GO:0031143//pseudopodium;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0097038//perinuclear endoplasmic reticulum;GO:0110158//calpain complex	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0001824//blastocyst development;GO:0006508//proteolysis;GO:0007520//myoblast fusion;GO:0007565//female pregnancy;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0016540//protein autoprocessing;GO:0032675//regulation of interleukin-6 production;GO:0035458//cellular response to interferon-beta;GO:0042542//response to hydrogen peroxide;GO:0048266//behavioral response to pain;GO:0051493//regulation of cytoskeleton organization;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:1901216//positive regulation of neuron death;GO:1901741//positive regulation of myoblast fusion;GO:2001247//positive regulation of phosphatidylcholine biosynthetic process	--
ENSG00000162910	18.729	22.105	20.148	22.765	23.068	25.851	275	323	232	243	286	218	MRPL55	mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:HGNC:16686]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000162923	21.005	18.932	17.549	15.848	19.176	19.323	2331	1987	1409	1241	1638	1494	WDR26	WD repeat domain 26 [Source:HGNC Symbol;Acc:HGNC:21208]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0034657//GID complex	GO:0005515//protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000162924	1.174	0.777	0.714	0.784	0.78	0.704	270.6	179.94	121.51	133.75	151.79	118.06	REL	"REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954]"	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: overview	ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko05203//Viral carcinogenesis	K09254;K09254;K09254	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071159//NF-kappaB complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010629//negative regulation of gene expression;GO:0032688//negative regulation of interferon-beta production;GO:0034097//response to cytokine;GO:0038061//NIK/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	RHD
ENSG00000162927	1.287	2.536	1.548	2.033	2.036	1.985	72	101	51	56	71	61	PUS10	pseudouridine synthase 10 [Source:HGNC Symbol;Acc:HGNC:26505]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0070878//primary miRNA binding;GO:0106029//tRNA pseudouridine synthase activity	GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0031053//primary miRNA processing;GO:0031119//tRNA pseudouridine synthesis	--
ENSG00000162928	7.279	6.361	6.97	5.61	6.16	7.087	636	577	426	354	453	446	PEX13	peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13344	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990429//peroxisomal importomer complex	GO:0005515//protein binding	"GO:0001561//fatty acid alpha-oxidation;GO:0001764//neuron migration;GO:0001967//suckling behavior;GO:0007626//locomotory behavior;GO:0015031//protein transport;GO:0016560//protein import into peroxisome matrix, docking;GO:0021795//cerebral cortex cell migration;GO:0060152//microtubule-based peroxisome localization"	--
ENSG00000162929	1.105	0.777	0.356	0.294	0.603	0.764	96	66	25	19	48	47	SANBR	SANT and BTB domain regulator of CSR [Source:HGNC Symbol;Acc:HGNC:29387]	-	-	-	-	-	-	-	--
ENSG00000162931	0.872	1.014	1.127	1.365	1.346	0.714	34	40	34	38	40	21	TRIM17	tripartite motif containing 17 [Source:HGNC Symbol;Acc:HGNC:13430]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005764//lysosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006914//autophagy;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0045087//innate immune response;GO:0051865//protein autoubiquitination	--
ENSG00000162944	0.827	0.879	0.858	0.444	1.09	0.355	93	56	61	37	41	29	RFTN2	raftlin family member 2 [Source:HGNC Symbol;Acc:HGNC:26402]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0033227//dsRNA transport;GO:0043330//response to exogenous dsRNA	--
ENSG00000162946	0.413	0.56	0.246	0.329	0.33	0.509	60.25	61.34	25.82	32	41	36	DISC1	DISC1 scaffold protein [Source:HGNC Symbol;Acc:HGNC:2888]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030286//dynein complex;GO:0030424//axon;GO:0036064//ciliary basal body;GO:0044297//cell body;GO:0045111//intermediate filament cytoskeleton;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0090724//central region of growth cone;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0060090//molecular adaptor activity	"GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002052//positive regulation of neuroblast proliferation;GO:0007399//nervous system development;GO:0010975//regulation of neuron projection development;GO:0010976//positive regulation of neuron projection development;GO:0016055//Wnt signaling pathway;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021846//cell proliferation in forebrain;GO:0021852//pyramidal neuron migration to cerebral cortex;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031929//TOR signaling;GO:0032091//negative regulation of protein binding;GO:0034613//cellular protein localization;GO:0045773//positive regulation of axon extension;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051602//response to electrical stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060070//canonical Wnt signaling pathway;GO:0060271//cilium assembly;GO:0060998//regulation of dendritic spine development;GO:0071539//protein localization to centrosome;GO:0090128//regulation of synapse maturation;GO:1905515//non-motile cilium assembly;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000162949	0	0	0.024	0	0.025	0	0	0	1	0	1	0	CAPN13	calpain 13 [Source:HGNC Symbol;Acc:HGNC:16663]	-	-	-	-	GO:0005737//cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0043066//negative regulation of apoptotic process	--
ENSG00000162951	0.317	0.334	0.031	0.7	1.006	1.319	14	16	1	28	37	44	LRRTM1	leucine rich repeat transmembrane neuronal 1 [Source:HGNC Symbol;Acc:HGNC:19408]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030426//growth cone;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002091//negative regulation of receptor internalization;GO:0007626//locomotory behavior;GO:0008150//biological_process;GO:0035418//protein localization to synapse;GO:0035640//exploration behavior;GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0060291//long-term synaptic potentiation	--
ENSG00000162959	12.259	9.156	12.062	11.45	10.572	14.095	417.02	308.15	308	279	311	334.43	MEMO1	mediator of cell motility 1 [Source:HGNC Symbol;Acc:HGNC:14014]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0032886//regulation of microtubule-based process	--
ENSG00000162961	23.203	23.648	25.323	22.985	20.4	26.014	330	338	266	242	245	268	DPY30	dpy-30 histone methyltransferase complex regulatory subunit [Source:HGNC Symbol;Acc:HGNC:24590]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006325//chromatin organization;GO:0016197//endosomal transport;GO:0051568//histone H3-K4 methylation	--
ENSG00000162971	2.68	1.896	1.873	1.357	2.241	1.757	201	152	105	87	153	88	TYW5	tRNA-yW synthesizing protein 5 [Source:HGNC Symbol;Acc:HGNC:26754]	-	-	-	-	GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0102524//tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity	GO:0008033//tRNA processing;GO:0031591//wybutosine biosynthetic process	--
ENSG00000162972	7.262	5.536	4.666	6.136	5.285	6.002	171	150	100	126	129	109	MAIP1	matrix AAA peptidase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:26198]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0007007//inner mitochondrial membrane organization;GO:0032979//protein insertion into mitochondrial inner membrane from matrix;GO:0036444//calcium import into the mitochondrion;GO:0051204//protein insertion into mitochondrial membrane;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000162975	0.021	0.126	0.285	0.17	0.174	0.26	1	6	10	6	7	9	KCNF1	potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000162976	3.896	4.027	4.77	4.443	4.846	4.701	140	144	115	119	149	112	SLC66A3	solute carrier family 66 member 3 [Source:HGNC Symbol;Acc:HGNC:28503]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000162980	19.338	12.613	9.517	15.674	18.084	18.562	1125.4	946.4	603.89	595.38	637.65	656.39	ARL5A	ADP ribosylation factor like GTPase 5A [Source:HGNC Symbol;Acc:HGNC:696]	-	-	-	-	GO:0005802//trans-Golgi network	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:1903292//protein localization to Golgi membrane	--
ENSG00000162981	6.647	6.407	8.273	6.883	6.874	8.444	701	628	605	528	565	617	LRATD1	LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0000902//cell morphogenesis;GO:0048870//cell motility	--
ENSG00000162989	0.656	0.952	0.88	1.399	1.317	1.798	63	89	60	98	101	120	KCNJ3	potassium inwardly rectifying channel subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:6264]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Endocrine system;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Endocrine system	ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04929//GnRH secretion	K04997;K04997;K04997;K04997;K04997;K04997;K04997;K04997;K04997;K04997	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0099056//integral component of presynaptic membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051602//response to electrical stimulus;GO:0071805//potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0099625//ventricular cardiac muscle cell membrane repolarization;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000162992	0	0.031	0	0	0	0.027	0	1	0	0	0	1	NEUROD1	neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08033	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0003326//pancreatic A cell fate commitment;GO:0003329//pancreatic PP cell fate commitment;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006913//nucleocytoplasmic transport;GO:0007263//nitric oxide mediated signal transduction;GO:0007399//nervous system development;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0009952//anterior/posterior pattern specification;GO:0021542//dentate gyrus development;GO:0021549//cerebellum development;GO:0022008//neurogenesis;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030902//hindbrain development;GO:0031018//endocrine pancreas development;GO:0035881//amacrine cell differentiation;GO:0035883//enteroendocrine cell differentiation;GO:0042593//glucose homeostasis;GO:0043010//camera-type eye development;GO:0043065//positive regulation of apoptotic process;GO:0045165//cell fate commitment;GO:0045597//positive regulation of cell differentiation;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0048562//embryonic organ morphogenesis;GO:0048666//neuron development;GO:0048839//inner ear development;GO:0050796//regulation of insulin secretion;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060730//regulation of intestinal epithelial structure maintenance;GO:0071333//cellular response to glucose stimulus;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:2000679//positive regulation of transcription regulatory region DNA binding"	bHLH
ENSG00000162994	1.051	0.847	1.486	0.845	0.58	1.653	79	53	58	35	45	51	CLHC1	clathrin heavy chain linker domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26453]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000162998	483.777	508.86	498.676	316.323	362.362	324.192	26461	27976	20145	12816	16745	12902	FRZB	frizzled related protein [Source:HGNC Symbol;Acc:HGNC:3959]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K25481	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0017147//Wnt-protein binding	GO:0001501//skeletal system development;GO:0008285//negative regulation of cell population proliferation;GO:0010721//negative regulation of cell development;GO:0014033//neural crest cell differentiation;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0042472//inner ear morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0045600//positive regulation of fat cell differentiation;GO:0048856//anatomical structure development;GO:0060029//convergent extension involved in organogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0061037//negative regulation of cartilage development;GO:0061053//somite development;GO:0070367//negative regulation of hepatocyte differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090103//cochlea morphogenesis	--
ENSG00000162999	0.641	0.977	0.839	0.351	0.644	0.498	69	70	38	28	46	39	DUSP19	dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894]	-	-	-	-	GO:0005737//cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004860//protein kinase inhibitor activity;GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008579//JUN kinase phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030295//protein kinase activator activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006469//negative regulation of protein kinase activity;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0032147//activation of protein kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043405//regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0043508//negative regulation of JUN kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0046329//negative regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade	--
ENSG00000163001	30.091	30.469	28.665	19.395	19.984	22.077	768	769	536	369	426	410	CFAP36	cilia and flagella associated protein 36 [Source:HGNC Symbol;Acc:HGNC:30540]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0035869//ciliary transition zone;GO:0042995//cell projection;GO:0043227//membrane-bounded organelle;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0047485//protein N-terminus binding	GO:0008150//biological_process	--
ENSG00000163002	6.887	6.236	5.385	5.832	5.59	5.73	200	187	114	122	135	116	NUP35	nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14313;K14313	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0044613//nuclear pore central transport channel;GO:0044615//nuclear pore nuclear basket	GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0017056//structural constituent of nuclear pore;GO:0042802//identical protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006607//NLS-bearing protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0006999//nuclear pore organization;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000163006	1.21	2.017	1.24	1.047	1.081	1.13	52	56	36	37	45	39	CCDC138	coiled-coil domain containing 138 [Source:HGNC Symbol;Acc:HGNC:26531]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163012	0	0.039	0	0	0	0	0	2	0	0	0	0	ZSWIM2	zinc finger SWIM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:30990]	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000163013	1.818	1.921	1.791	2.143	2.368	1.771	266	287	192	230	296	189	FBXO41	F-box protein 41 [Source:HGNC Symbol;Acc:HGNC:29409]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000163017	2.807	3.654	3.727	0	0	0.141	62	62	54	0	0	3	ACTG2	"actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145]"	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K12315	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0032982//myosin filament;GO:0044297//cell body;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0072562//blood microparticle	GO:0000166//nucleotide binding;GO:0005524//ATP binding	GO:0010628//positive regulation of gene expression;GO:0090131//mesenchyme migration	--
ENSG00000163026	4.368	3.291	4.126	3.772	3.485	4.277	327	264	242	223	235	195	WDCP	WD repeat and coiled coil containing [Source:HGNC Symbol;Acc:HGNC:26157]	-	-	-	-	-	GO:0005515//protein binding;GO:0019900//kinase binding	GO:0051259//protein complex oligomerization	--
ENSG00000163029	29.606	19.903	19.919	15.268	22.566	21.361	2411	1815	1256	947	1461	1294	SMC6	structural maintenance of chromosomes 6 [Source:HGNC Symbol;Acc:HGNC:20466]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000781//chromosome, telomeric region;GO:0000803//sex chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0030915//Smc5-Smc6 complex;GO:0035061//interchromatin granule;GO:0035861//site of double-strand break;GO:0097431//mitotic spindle pole"	GO:0000166//nucleotide binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding	GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0032204//regulation of telomere maintenance;GO:0051984//positive regulation of chromosome segregation;GO:0090398//cellular senescence	--
ENSG00000163032	0.234	0.27	0.361	0.268	0.466	0.321	10	8	7	10	8	8	VSNL1	visinin like 1 [Source:HGNC Symbol;Acc:HGNC:12722]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045921//positive regulation of exocytosis;GO:0046676//negative regulation of insulin secretion	--
ENSG00000163040	17.313	16.737	19.314	20.468	17.543	21.527	471.73	461.88	386.37	417.81	402.63	423.61	CCDC74A	coiled-coil domain containing 74A [Source:HGNC Symbol;Acc:HGNC:25197]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163041	199.839	192.788	192.354	177.57	164.467	187.654	4341	4275	3124	2908	3068	2910	H3-3A	H3.3 histone A [Source:HGNC Symbol;Acc:HGNC:4764]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0001740//Barr body;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome"	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity	GO:0001649//osteoblast differentiation;GO:0006334//nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006997//nucleus organization;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007338//single fertilization;GO:0007566//embryo implantation;GO:0008283//cell population proliferation;GO:0008584//male gonad development;GO:0030307//positive regulation of cell growth;GO:0031508//pericentric heterochromatin assembly;GO:0031509//subtelomeric heterochromatin assembly;GO:0032200//telomere organization;GO:0035264//multicellular organism growth;GO:0042692//muscle cell differentiation;GO:0048477//oogenesis;GO:0090230//regulation of centromere complex assembly;GO:1902340//negative regulation of chromosome condensation	--
ENSG00000163046	0.343	0.46	0.297	0.624	0.438	0.508	11	15	7	15	12	12	ANKRD30BL	ankyrin repeat domain 30B like [Source:HGNC Symbol;Acc:HGNC:35167]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163050	5.82	6.21	7.28	6.842	7.3	6.108	345.99	367.16	319.63	299.59	366.64	262.43	COQ8A	coenzyme Q8A [Source:HGNC Symbol;Acc:HGNC:16812]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031314//extrinsic component of mitochondrial inner membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043531//ADP binding	GO:0006744//ubiquinone biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000163053	56.109	50.886	62.412	58.191	59.341	72.14	4462	4155	3585	3391	3915	3752	SLC16A14	solute carrier family 16 member 14 [Source:HGNC Symbol;Acc:HGNC:26417]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport	--
ENSG00000163060	0.064	0	0	0	0	0	2	0	0	0	0	0	TEKT4	tektin 4 [Source:HGNC Symbol;Acc:HGNC:31012]	-	-	-	-	GO:0005634//nucleus;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility	--
ENSG00000163064	0.02	0	0	0	0.024	0.027	1	0	0	0	1	1	EN1	engrailed homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3342]	Environmental Information Processing	Signal transduction	ko04341//Hedgehog signaling pathway - fly	K09319	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0008344//adult locomotory behavior;GO:0009653//anatomical structure morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0021549//cerebellum development;GO:0030182//neuron differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0030917//midbrain-hindbrain boundary development;GO:0035115//embryonic forelimb morphogenesis;GO:0035176//social behavior;GO:0035264//multicellular organism growth;GO:0042220//response to cocaine;GO:0042756//drinking behavior;GO:0043473//pigmentation;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048666//neuron development;GO:0060173//limb development;GO:0061743//motor learning;GO:0071542//dopaminergic neuron differentiation;GO:1901215//negative regulation of neuron death;GO:1990403//embryonic brain development"	Homeobox
ENSG00000163069	20.349	17.456	18.778	15.076	16.776	16.019	1793	1546	1222	984	1231	1027	SGCB	sarcoglycan beta [Source:HGNC Symbol;Acc:HGNC:10806]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12566;K12566;K12566;K12566	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016011//dystroglycan complex;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0007517//muscle organ development;GO:0055001//muscle cell development;GO:0055013//cardiac muscle cell development;GO:0097084//vascular associated smooth muscle cell development	--
ENSG00000163071	0.287	0.798	0.113	0.731	0.173	0.259	24	40	6	10	7	11	SPATA18	spermatogenesis associated 18 [Source:HGNC Symbol;Acc:HGNC:29579]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0035694//mitochondrial protein catabolic process;GO:0035695//mitophagy by induced vacuole formation	--
ENSG00000163072	0	0.033	0.082	0	0.072	0	0	1	1	0	1	0	NOSTRIN	nitric oxide synthase trafficking [Source:HGNC Symbol;Acc:HGNC:20203]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030666//endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016191//synaptic vesicle uncoating;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000163075	3.491	2.426	2.363	1.215	1.617	1.373	107	82	42	36	66	36	CFAP221	cilia and flagella associated protein 221 [Source:HGNC Symbol;Acc:HGNC:33720]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0005516//calmodulin binding	GO:0003341//cilium movement;GO:0030030//cell projection organization;GO:0044458//motile cilium assembly;GO:0060271//cilium assembly;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance	--
ENSG00000163082	0	0.048	0.052	0.157	0.103	0.066	0	5	4	12	9	5	SGPP2	sphingosine-1-phosphate phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:19953]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04717;K04717;K04717	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0070780//dihydrosphingosine-1-phosphate phosphatase activity	GO:0006629//lipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046839//phospholipid dephosphorylation;GO:0061469//regulation of type B pancreatic cell proliferation	--
ENSG00000163083	0.511	0.524	0.102	0.305	0.285	0.062	34	35	5	15	16	3	INHBB	inhibin subunit beta B [Source:HGNC Symbol;Acc:HGNC:6067]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K22687;K22687;K22687	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043513//inhibin B complex;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery	GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0034711//inhibin binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046789//host cell surface receptor binding	GO:0001541//ovarian follicle development;GO:0006952//defense response;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009267//cellular response to starvation;GO:0009611//response to wounding;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014070//response to organic cyclic compound;GO:0017085//response to insecticide;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0032686//negative regulation of hepatocyte growth factor production;GO:0032869//cellular response to insulin stimulus;GO:0032924//activin receptor signaling pathway;GO:0034698//response to gonadotropin;GO:0044320//cellular response to leptin stimulus;GO:0044650//adhesion of symbiont to host cell;GO:0045444//fat cell differentiation;GO:0046676//negative regulation of insulin secretion;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0048599//oocyte development;GO:0060279//positive regulation of ovulation;GO:0060395//SMAD protein signal transduction;GO:0071277//cellular response to calcium ion;GO:0071320//cellular response to cAMP;GO:0071347//cellular response to interleukin-1;GO:0071397//cellular response to cholesterol;GO:0071407//cellular response to organic cyclic compound;GO:0072520//seminiferous tubule development;GO:0097067//cellular response to thyroid hormone stimulus;GO:1904017//cellular response to Thyroglobulin triiodothyronine;GO:1990636//reproductive senescence;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000163092	0.017	0	0	0	0.079	0	1	0	0	0	4	0	XIRP2	xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303]	-	-	-	-	GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0030054//cell junction	GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0051393//alpha-actinin binding	GO:0003281//ventricular septum development;GO:0007015//actin filament organization;GO:0007507//heart development;GO:0008150//biological_process;GO:0030036//actin cytoskeleton organization;GO:0045216//cell-cell junction organization;GO:0055008//cardiac muscle tissue morphogenesis	--
ENSG00000163093	6.02	5.733	6.731	7.982	6.965	6.945	391.84	376.72	323.72	349.94	383.99	329.31	BBS5	Bardet-Biedl syndrome 5 [Source:HGNC Symbol;Acc:HGNC:970]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0034451//centriolar satellite;GO:0034464//BBSome;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001947//heart looping;GO:0007601//visual perception;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0032402//melanosome transport;GO:0044458//motile cilium assembly;GO:0046907//intracellular transport;GO:0050896//response to stimulus;GO:0060271//cilium assembly	--
ENSG00000163104	10.531	7.252	7.793	6.313	7.42	8.158	1026	747	574	453	633	611	SMARCAD1	"SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 [Source:HGNC Symbol;Acc:HGNC:18398]"	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K14439	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0035861//site of double-strand break;GO:0043596//nuclear replication fork	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043130//ubiquitin binding;GO:0140658//ATP-dependent chromatin remodeler activity"	GO:0000018//regulation of DNA recombination;GO:0000729//DNA double-strand break processing;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:0051304//chromosome separation;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation	--
ENSG00000163106	0	0	0	0	0	0	0	0	0	0	0	0	HPGDS	hematopoietic prostaglandin D synthase [Source:HGNC Symbol;Acc:HGNC:17890]	Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K04097;K04097;K04097;K04097;K04097;K04097	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000287//magnesium ion binding;GO:0004364//glutathione transferase activity;GO:0004667//prostaglandin-D synthase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016853//isomerase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0006749//glutathione metabolic process;GO:0007165//signal transduction;GO:0007626//locomotory behavior;GO:2000255//negative regulation of male germ cell proliferation	--
ENSG00000163110	91.031	83.176	85.192	68.276	79.866	82.133	9270	8347	6403	5206	6665	5710	PDLIM5	PDZ and LIM domain 5 [Source:HGNC Symbol;Acc:HGNC:17468]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse	GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0042805//actinin binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0051963//regulation of synapse assembly;GO:0061001//regulation of dendritic spine morphogenesis;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0061061//muscle structure development;GO:0098609//cell-cell adhesion	--
ENSG00000163114	0	0	0	0	0	0	0	0	0	0	0	0	PDHA2	pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Signal transduction;Global and overview maps;Endocrine system;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K00161;K00161;K00161;K00161;K00161;K00161;K00161;K00161;K00161	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0034604//pyruvate dehydrogenase (NAD+) activity"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0006090//pyruvate metabolic process;GO:0006099//tricarboxylic acid cycle	--
ENSG00000163116	0.051	0.025	0	0	0	0	2	1	0	0	0	0	STPG2	sperm tail PG-rich repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:28712]	-	-	-	-	-	-	-	--
ENSG00000163121	0.165	0	0.134	0.078	0	0.04	5	0	3	2	0	1	NEURL3	neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162]	-	-	-	-	-	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000163125	10.854	10.831	10.519	8.912	9.675	10.004	1791	1791	1278	1086	1355	1205	RPRD2	regulation of nuclear pre-mRNA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29039]	-	-	-	-	"GO:0005654//nucleoplasm;GO:0016591//RNA polymerase II, holoenzyme"	GO:0000993//RNA polymerase II complex binding	GO:0031124//mRNA 3'-end processing	--
ENSG00000163126	0.241	0.257	0.403	0.408	0.325	0.485	12.48	13.26	13.38	13.5	14.73	17.5	ANKRD23	ankyrin repeat domain 23 [Source:HGNC Symbol;Acc:HGNC:24470]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0005515//protein binding;GO:0031432//titin binding	-	--
ENSG00000163131	0.098	0.149	0.178	0	0.372	0	4	6	4	0	10	0	CTSS	cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545]	Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Cell growth and death;Transport and catabolism;Immune system	ko05152//Tuberculosis;ko04145//Phagosome;ko04210//Apoptosis;ko04142//Lysosome;ko04612//Antigen processing and presentation	K01368;K01368;K01368;K01368;K01368	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005770//late endosome;GO:0031410//cytoplasmic vesicle;GO:0036021//endolysosome lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0062023//collagen-containing extracellular matrix;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0001968//fibronectin binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043236//laminin binding;GO:0043394//proteoglycan binding	GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0006508//proteolysis;GO:0006955//immune response;GO:0010447//response to acidic pH;GO:0016485//protein processing;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0034769//basement membrane disassembly;GO:0048002//antigen processing and presentation of peptide antigen;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0097067//cellular response to thyroid hormone stimulus;GO:2001259//positive regulation of cation channel activity	--
ENSG00000163132	0.422	0.593	0.505	0.604	0.677	0.615	17	24	15	18	23	18	MSX1	msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K09341	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000902//cell morphogenesis;GO:0001701//in utero embryonic development;GO:0001837//epithelial to mesenchymal transition;GO:0003007//heart morphogenesis;GO:0003161//cardiac conduction system development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0010463//mesenchymal cell proliferation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030308//negative regulation of cell growth;GO:0030326//embryonic limb morphogenesis;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0034504//protein localization to nucleus;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035880//embryonic nail plate morphogenesis;GO:0042474//middle ear morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042476//odontogenesis;GO:0042481//regulation of odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048598//embryonic morphogenesis;GO:0048863//stem cell differentiation;GO:0050821//protein stabilization;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0060349//bone morphogenesis;GO:0060536//cartilage morphogenesis;GO:0061180//mammary gland epithelium development;GO:0061312//BMP signaling pathway involved in heart development;GO:0090427//activation of meiosis;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2001055//positive regulation of mesenchymal cell apoptotic process"	Homeobox
ENSG00000163138	4.773	4.775	6.572	4.82	3.431	2.941	151.78	139	131	98.82	115.67	91	PACRGL	parkin coregulated like [Source:HGNC Symbol;Acc:HGNC:28442]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163141	0.275	0.081	0.11	0.039	0.205	0	9	2	2	2	5	0	BNIPL	BCL2 interacting protein like [Source:HGNC Symbol;Acc:HGNC:16976]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0040009//regulation of growth rate	--
ENSG00000163145	1.239	0.988	0.948	0.256	0.317	0.445	111	89	43	17	24	29	C1QTNF7	C1q and TNF related 7 [Source:HGNC Symbol;Acc:HGNC:14342]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer	GO:0005515//protein binding	-	--
ENSG00000163154	0	0	0	0	0.049	0	0	0	0	0	1	0	TNFAIP8L2	TNF alpha induced protein 8 like 2 [Source:HGNC Symbol;Acc:HGNC:26277]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0002376//immune system process;GO:0042981//regulation of apoptotic process;GO:0045087//innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0050868//negative regulation of T cell activation	--
ENSG00000163155	4.155	4.78	4.517	3.992	4.149	5.321	197	218	144	151	179	181	LYSMD1	LysM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:32070]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000163156	8.957	8.785	7.676	9.06	9.488	10.128	186	179	112	114	143	144	SCNM1	sodium channel modifier 1 [Source:HGNC Symbol;Acc:HGNC:23136]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000163157	0	0	0	0	0	0	0	0	0	0	0	0	TMOD4	tropomodulin 4 [Source:HGNC Symbol;Acc:HGNC:11874]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0030016//myofibril	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0030239//myofibril assembly;GO:0051694//pointed-end actin filament capping	--
ENSG00000163159	19.176	20.809	21.934	23.907	22.197	18.841	601	653	507	553	585	429	VPS72	vacuolar protein sorting 72 homolog [Source:HGNC Symbol;Acc:HGNC:11644]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0032991//protein-containing complex;GO:0035267//NuA4 histone acetyltransferase complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0035019//somatic stem cell population maintenance;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000163161	17.078	15.526	20.013	16.64	16.207	19.388	886	872	738	626	729	721	ERCC3	"ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435]"	Genetic Information Processing;Genetic Information Processing	Transcription;Replication and repair	ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K10843;K10843	GO:0000112//nucleotide-excision repair factor 3 complex;GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0097550//transcription preinitiation complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003684//damaged DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043138//3'-5' DNA helicase activity;GO:0047485//protein N-terminus binding;GO:1990841//promoter-specific chromatin binding	"GO:0000717//nucleotide-excision repair, DNA duplex unwinding;GO:0001666//response to hypoxia;GO:0006265//DNA topological change;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0008104//protein localization;GO:0009411//response to UV;GO:0009650//UV protection;GO:0032508//DNA duplex unwinding;GO:0033683//nucleotide-excision repair, DNA incision;GO:0035315//hair cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0048568//embryonic organ development;GO:1901990//regulation of mitotic cell cycle phase transition"	--
ENSG00000163162	14.213	14.693	15.602	16.564	15.621	20.615	848.3	869	683	736	796	901	RNF149	ring finger protein 149 [Source:HGNC Symbol;Acc:HGNC:23137]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031647//regulation of protein stability;GO:0043409//negative regulation of MAPK cascade;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000163166	14.499	14.853	12.813	8.407	10.146	10.063	890	915	577	384	504	442	IWS1	"interacts with SUPT6H, CTD assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:25467]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010793//regulation of mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:0090239//regulation of histone H4 acetylation;GO:2001253//regulation of histone H3-K36 trimethylation	--
ENSG00000163170	10.768	9.161	12.977	9.917	9.615	14.53	116	99	103	77	87	112	BOLA3	bolA family member 3 [Source:HGNC Symbol;Acc:HGNC:24415]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016604//nuclear body;GO:1990229//iron-sulfur cluster assembly complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0016226//iron-sulfur cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000163171	13.418	12.233	9.272	9.118	7.915	9.539	730	689	413	351	383	420	CDC42EP3	CDC42 effector protein 3 [Source:HGNC Symbol;Acc:HGNC:16943]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0005519//cytoskeletal regulatory protein binding	GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly	--
ENSG00000163191	66.879	71.905	57.393	53.41	57.876	54.021	781	844	495	462	571	459	S100A11	S100 calcium binding protein A11 [Source:HGNC Symbol;Acc:HGNC:10488]	-	-	-	-	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0007165//signal transduction;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell population proliferation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0042127//regulation of cell population proliferation;GO:0098609//cell-cell adhesion	--
ENSG00000163202	0	0	0	0	0	0	0	0	0	0	0	0	LCE3D	late cornified envelope 3D [Source:HGNC Symbol;Acc:HGNC:16615]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000163206	0	0	0	0	0	0	0	0	0	0	0	0	SMCP	sperm mitochondria associated cysteine rich protein [Source:HGNC Symbol;Acc:HGNC:6962]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007338//single fertilization;GO:0007341//penetration of zona pellucida;GO:0030317//flagellated sperm motility	--
ENSG00000163207	0.022	0	0.061	0	0	0	1	0	2	0	0	0	IVL	involucrin [Source:HGNC Symbol;Acc:HGNC:6187]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0010224//response to UV-B;GO:0018149//peptide cross-linking;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000163209	0	0	0	0	0.063	0	0	0	0	0	1	0	SPRR3	small proline rich protein 3 [Source:HGNC Symbol;Acc:HGNC:11268]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization;GO:0042060//wound healing	--
ENSG00000163214	5.675	4.253	4.524	3.744	4.158	4.137	575	427	328	281	352	305	DHX57	DExH-box helicase 57 [Source:HGNC Symbol;Acc:HGNC:20086]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	-	--
ENSG00000163216	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2D	small proline rich protein 2D [Source:HGNC Symbol;Acc:HGNC:11264]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000163217	0	0.016	0	0	0	0	0	2	0	0	0	0	BMP10	bone morphogenetic protein 10 [Source:HGNC Symbol;Acc:HGNC:20869]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22670	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0030018//Z disc	GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0031433//telethonin binding;GO:0033612//receptor serine/threonine kinase binding	"GO:0001822//kidney development;GO:0007155//cell adhesion;GO:0007507//heart development;GO:0007512//adult heart development;GO:0010596//negative regulation of endothelial cell migration;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0045214//sarcomere organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055015//ventricular cardiac muscle cell development;GO:0055117//regulation of cardiac muscle contraction;GO:0060038//cardiac muscle cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060298//positive regulation of sarcomere organization;GO:0060347//heart trabecula formation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0061036//positive regulation of cartilage development;GO:1903242//regulation of cardiac muscle hypertrophy in response to stress;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis"	--
ENSG00000163218	0	0	0	0	0	0	0	0	0	0	0	0	PGLYRP4	peptidoglycan recognition protein 4 [Source:HGNC Symbol;Acc:HGNC:30015]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0008270//zinc ion binding;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0016019//peptidoglycan immune receptor activity;GO:0042834//peptidoglycan binding;GO:0046982//protein heterodimerization activity	GO:0002376//immune system process;GO:0009253//peptidoglycan catabolic process;GO:0016045//detection of bacterium;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000163219	0.416	0.481	0.279	0.32	0.275	0.247	17	21	7	10	7	5	ARHGAP25	Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]	-	-	-	-	GO:0001891//phagocytic cup	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity"	--
ENSG00000163220	0	0	0	0	2.091	0	0	0	0	0	21	0	S100A9	S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21128	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0034774//secretory granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0016209//antioxidant activity;GO:0035662//Toll-like receptor 4 binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050544//arachidonic acid binding;GO:0050786//RAGE receptor binding	GO:0002376//immune system process;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002544//chronic inflammatory response;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0010976//positive regulation of neuron projection development;GO:0014002//astrocyte development;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0030307//positive regulation of cell growth;GO:0030593//neutrophil chemotaxis;GO:0032119//sequestering of zinc ion;GO:0032496//response to lipopolysaccharide;GO:0035425//autocrine signaling;GO:0035606//peptidyl-cysteine S-trans-nitrosylation;GO:0035821//modulation of process of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0045113//regulation of integrin biosynthetic process;GO:0050729//positive regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051493//regulation of cytoskeleton organization;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070488//neutrophil aggregation;GO:0098869//cellular oxidant detoxification;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000163221	0	0	0	0	0	0	0	0	0	0	0	0	S100A12	S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034774//secretory granule lumen	GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050786//RAGE receptor binding	GO:0002376//immune system process;GO:0002548//monocyte chemotaxis;GO:0006805//xenobiotic metabolic process;GO:0006954//inflammatory response;GO:0030593//neutrophil chemotaxis;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0045576//mast cell activation;GO:0050729//positive regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000163235	0.386	0.699	0.988	0.775	0.762	1.215	33	52	37	49	55	50	TGFA	transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05225//Hepatocellular carcinoma;ko04915//Estrogen signaling pathway;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05211//Renal cell carcinoma;ko05223//Non-small cell lung cancer	K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774;K08774	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0035556//intracellular signal transduction;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:0060749//mammary gland alveolus development;GO:0072574//hepatocyte proliferation	--
ENSG00000163239	0	0	0	0	0	0	0	0	0	0	0	0	TDRD10	tudor domain containing 10 [Source:HGNC Symbol;Acc:HGNC:25316]	-	-	-	-	GO:0043186//P granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	GO:0030719//P granule organization;GO:0034587//piRNA metabolic process	--
ENSG00000163249	6.468	6.725	6.395	6.463	5.261	5.577	444	401	283	287	316	280	CCNYL1	cyclin Y like 1 [Source:HGNC Symbol;Acc:HGNC:26868]	-	-	-	-	GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045859//regulation of protein kinase activity;GO:0060828//regulation of canonical Wnt signaling pathway	--
ENSG00000163251	10.281	9.41	8.643	5.492	6.899	6.533	1501	1381	932	594	851	694	FZD5	frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375	GO:0000139//Golgi membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0017147//Wnt-protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042813//Wnt-activated receptor activity;GO:0044877//protein-containing complex binding	"GO:0000578//embryonic axis specification;GO:0001525//angiogenesis;GO:0001944//vasculature development;GO:0002726//positive regulation of T cell cytokine production;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007416//synapse assembly;GO:0008285//negative regulation of cell population proliferation;GO:0008595//anterior/posterior axis specification, embryo;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0031076//embryonic camera-type eye development;GO:0031077//post-embryonic camera-type eye development;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033077//T cell differentiation in thymus;GO:0043507//positive regulation of JUN kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048596//embryonic camera-type eye morphogenesis;GO:0060061//Spemann organizer formation;GO:0060070//canonical Wnt signaling pathway;GO:0060561//apoptotic process involved in morphogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060715//syncytiotrophoblast cell differentiation involved in labyrinthine layer development;GO:0060716//labyrinthine layer blood vessel development;GO:0060718//chorionic trophoblast cell differentiation;GO:0071219//cellular response to molecule of bacterial origin;GO:1901382//regulation of chorionic trophoblast cell proliferation;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:2000810//regulation of bicellular tight junction assembly"	--
ENSG00000163254	0	0	0	0	0	0	0	0	0	0	0	0	CRYGC	crystallin gamma C [Source:HGNC Symbol;Acc:HGNC:2410]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000163257	3.032	2.764	2.986	2.247	2.598	3.658	286	262	208	157	207	251	DCAF16	DDB1 and CUL4 associated factor 16 [Source:HGNC Symbol;Acc:HGNC:25987]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000163263	0	0.142	0.097	0	0	0.197	0	2	1	0	0	2	CFAP141	cilia and flagella associated protein 141 [Source:HGNC Symbol;Acc:HGNC:32305]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163273	0	0	0	0	0	0	0	0	0	0	0	0	NPPC	natriuretic peptide C [Source:HGNC Symbol;Acc:HGNC:7941]	Environmental Information Processing;Human Diseases;Organismal Systems	Signal transduction;Cardiovascular disease;Circulatory system	ko04022//cGMP-PKG signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04270//Vascular smooth muscle contraction	K12336;K12336;K12336	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0032991//protein-containing complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0051427//hormone receptor binding	GO:0001503//ossification;GO:0001666//response to hypoxia;GO:0003418//growth plate cartilage chondrocyte differentiation;GO:0003419//growth plate cartilage chondrocyte proliferation;GO:0006182//cGMP biosynthetic process;GO:0006457//protein folding;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009791//post-embryonic development;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0022414//reproductive process;GO:0032966//negative regulation of collagen biosynthetic process;GO:0040014//regulation of multicellular organism growth;GO:0045471//response to ethanol;GO:0045669//positive regulation of osteoblast differentiation;GO:0048513//animal organ development;GO:0048660//regulation of smooth muscle cell proliferation;GO:0051447//negative regulation of meiotic cell cycle;GO:1900194//negative regulation of oocyte maturation;GO:2000279//negative regulation of DNA biosynthetic process	--
ENSG00000163281	7.953	8.026	6.134	5.938	7.782	8.672	358	318	179	189	271	252	GNPDA2	glucosamine-6-phosphate deaminase 2 [Source:HGNC Symbol;Acc:HGNC:21526]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K02564;K02564	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004342//glucosamine-6-phosphate deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0005975//carbohydrate metabolic process;GO:0006043//glucosamine catabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0019262//N-acetylneuraminate catabolic process	--
ENSG00000163283	0	0.104	0	0.047	0.166	0.12	0	6	0	2	8	5	ALPP	"alkaline phosphatase, placental [Source:HGNC Symbol;Acc:HGNC:439]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis;ko00730//Thiamine metabolism	K01077;K01077;K01077	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004035//alkaline phosphatase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000163285	0.007	0	0	0	0	0	1	0	0	0	0	0	GABRG1	gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05186;K05186;K05186;K05186;K05186	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0050811//GABA receptor binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000163286	0	0	0	0	0	0	0	0	0	0	0	0	ALPG	"alkaline phosphatase, germ cell [Source:HGNC Symbol;Acc:HGNC:441]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis;ko00730//Thiamine metabolism	K01077;K01077;K01077	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0003824//catalytic activity;GO:0004035//alkaline phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000163288	0.34	0.297	0.15	0.134	0.147	0.176	6	12	2	4	4	5	GABRB1	gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko04726//Serotonergic synapse;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05181;K05181;K05181;K05181;K05181;K05181	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005253//anion channel activity;GO:0005254//chloride channel activity;GO:0015276//ligand-gated ion channel activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0050811//GABA receptor binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0009636//response to toxic substance;GO:0021954//central nervous system neuron development;GO:0032570//response to progesterone;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0042698//ovulation cycle;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0071420//cellular response to histamine;GO:1902476//chloride transmembrane transport	--
ENSG00000163291	5.477	5.004	4.715	4.545	4.445	4.996	432.9	427.7	259.89	248.18	287.13	257.16	PAQR3	progestin and adipoQ receptor family member 3 [Source:HGNC Symbol;Acc:HGNC:30130]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001933//negative regulation of protein phosphorylation;GO:0010977//negative regulation of neuron projection development;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034067//protein localization to Golgi apparatus;GO:0043407//negative regulation of MAP kinase activity	--
ENSG00000163293	0.751	0.545	0.751	0.454	0.301	0.669	68	57	61	37	23	49	NIPAL1	NIPA like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27194]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015095//magnesium ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015693//magnesium ion transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000163295	0	0	0	0	0	0	0	0	0	0	0	0	ALPI	"alkaline phosphatase, intestinal [Source:HGNC Symbol;Acc:HGNC:437]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis;ko00730//Thiamine metabolism	K01077;K01077;K01077	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0000287//magnesium ion binding;GO:0002020//protease binding;GO:0003824//catalytic activity;GO:0004035//alkaline phosphatase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000163297	3.997	4.69	2.866	3.35	2.901	2.63	315	354	157	175	194	150	ANTXR2	ANTXR cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:21732]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20909	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	GO:1901998//toxin transport	--
ENSG00000163312	1.974	1.92	1.986	1.609	2.187	1.71	144	140	104	86	132	91	HELQ	"helicase, POLQ like [Source:HGNC Symbol;Acc:HGNC:18536]"	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:1990518//single-stranded 3'-5' DNA helicase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006364//rRNA processing;GO:0006807//nitrogen compound metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:0043170//macromolecule metabolic process	--
ENSG00000163319	11.97	8.653	7.698	8.468	9.783	11.508	286.78	229.51	154.27	181.59	197.06	193.01	MRPS18C	mitochondrial ribosomal protein S18C [Source:HGNC Symbol;Acc:HGNC:16633]	Genetic Information Processing	Translation	ko03010//Ribosome	K02963	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0070181//small ribosomal subunit rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000163320	34.688	27.276	30.238	22.007	28.594	29.928	2777	2253	1813	1442	1833	1827	CGGBP1	CGG triplet repeat binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1888]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000163322	7.123	4.562	7.209	5.376	5.854	5.011	317.22	185.49	210.73	182.41	206.94	153.99	ABRAXAS1	"abraxas 1, BRCA1 A complex subunit [Source:HGNC Symbol;Acc:HGNC:25829]"	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K20774	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0070531//BRCA1-A complex	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint;GO:0045739//positive regulation of DNA repair;GO:0070536//protein K63-linked deubiquitination;GO:0070537//histone H2A K63-linked deubiquitination;GO:0090307//mitotic spindle assembly	--
ENSG00000163328	3.079	2.243	2.034	1.415	1.868	2.074	330	250	165	121	191	170	GPR155	G protein-coupled receptor 155 [Source:HGNC Symbol;Acc:HGNC:22951]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0035556//intracellular signal transduction;GO:0050890//cognition;GO:0055085//transmembrane transport	--
ENSG00000163331	41.384	37.789	39.002	33.945	29.908	34.886	473	434	329	288	290	290	DAPL1	death associated protein like 1 [Source:HGNC Symbol;Acc:HGNC:21490]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0070513//death domain binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010507//negative regulation of autophagy;GO:0030154//cell differentiation;GO:0034198//cellular response to amino acid starvation;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0097190//apoptotic signaling pathway	--
ENSG00000163344	14.338	14.983	17.85	21.371	19.819	19.706	298	313	274	329	348	298	PMVK	phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00900//Terpenoid backbone biosynthesis	K13273;K13273;K13273	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004631//phosphomevalonate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	"GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0016310//phosphorylation;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0070723//response to cholesterol"	--
ENSG00000163346	93.187	96.191	109.773	103.514	106.535	108.696	4983	5101	4308	4077	4866	4139	PBXIP1	PBX homeobox interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21199]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane	GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0002532//production of molecular mediator involved in inflammatory response;GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0016477//cell migration;GO:0022617//extracellular matrix disassembly;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061975//articular cartilage development;GO:0097043//histone H3-K56 acetylation;GO:1901148//gene expression involved in extracellular matrix organization;GO:1902732//positive regulation of chondrocyte proliferation;GO:2001106//regulation of Rho guanyl-nucleotide exchange factor activity"	--
ENSG00000163347	8.142	8.045	6.744	12.881	12.387	11.672	582	578	356	682	748	607	CLDN1	claudin 1 [Source:HGNC Symbol;Acc:HGNC:2032]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0070160//tight junction	GO:0001618//virus receptor activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007568//aging;GO:0008065//establishment of blood-nerve barrier;GO:0009636//response to toxic substance;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0030335//positive regulation of cell migration;GO:0032496//response to lipopolysaccharide;GO:0034331//cell junction maintenance;GO:0035633//maintenance of blood-brain barrier;GO:0042538//hyperosmotic salinity response;GO:0045216//cell-cell junction organization;GO:0045471//response to ethanol;GO:0046718//viral entry into host cell;GO:0051259//protein complex oligomerization;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0061436//establishment of skin barrier;GO:0061772//xenobiotic transport across blood-nerve barrier;GO:0070673//response to interleukin-18;GO:0070830//bicellular tight junction assembly;GO:0071284//cellular response to lead ion;GO:0071346//cellular response to interferon-gamma;GO:0071356//cellular response to tumor necrosis factor;GO:0071548//response to dexamethasone;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090303//positive regulation of wound healing;GO:0090557//establishment of endothelial intestinal barrier;GO:0097421//liver regeneration;GO:1903348//positive regulation of bicellular tight junction assembly;GO:1903545//cellular response to butyrate	--
ENSG00000163348	19.323	19.478	21.739	23.854	20.86	23.629	1237	1262	1059	1110	1161	1134	PYGO2	pygopus family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:30257]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990907//beta-catenin-TCF complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035034//histone acetyltransferase regulator activity;GO:0042393//histone binding;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0002088//lens development in camera-type eye;GO:0007286//spermatid development;GO:0007289//spermatid nucleus differentiation;GO:0007420//brain development;GO:0016055//Wnt signaling pathway;GO:0030879//mammary gland development;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0035065//regulation of histone acetylation;GO:0035563//positive regulation of chromatin binding;GO:0048589//developmental growth;GO:0048856//anatomical structure development;GO:0051569//regulation of histone H3-K4 methylation;GO:0060021//roof of mouth development;GO:0060070//canonical Wnt signaling pathway	--
ENSG00000163349	15.605	14.987	15.372	11.998	14.246	13.591	2528	2445	1853	1501	1807	1634	HIPK1	homeodomain interacting protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:19006]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K08826	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016605//PML body;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001654//eye development;GO:0006468//protein phosphorylation;GO:0007224//smoothened signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0010842//retina layer formation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030182//neuron differentiation;GO:0034333//adherens junction assembly;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045766//positive regulation of angiogenesis;GO:0048596//embryonic camera-type eye morphogenesis;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0060216//definitive hemopoiesis;GO:0060235//lens induction in camera-type eye;GO:0061072//iris morphogenesis;GO:0072577//endothelial cell apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway	--
ENSG00000163352	0.074	0	0	0	0	0	1	0	0	0	0	0	LENEP	lens epithelial protein [Source:HGNC Symbol;Acc:HGNC:14429]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0007275//multicellular organism development	--
ENSG00000163354	0.167	0.04	0.054	0	0	0	5	2	2	0	0	0	DCST2	DC-STAMP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26562]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000163357	0	0	0.089	0	0.03	0	0	0	3	0	1	0	DCST1	DC-STAMP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26539]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002376//immune system process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0045087//innate immune response;GO:0060339//negative regulation of type I interferon-mediated signaling pathway	--
ENSG00000163359	0.042	0.006	0.069	0.028	0.722	0	1	1	4	2	32	0	COL6A3	collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K06238;K06238;K06238;K06238;K06238	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005589//collagen type VI trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0042383//sarcolemma;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030414//peptidase inhibitor activity	GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000163362	1.254	1.41	1.805	2.062	1.935	1.278	111	98	58	74	79	55	INAVA	innate immunity activator [Source:HGNC Symbol;Acc:HGNC:25599]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0005515//protein binding	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0031398//positive regulation of protein ubiquitination;GO:0032494//response to peptidoglycan;GO:0032495//response to muramyl dipeptide;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0034334//adherens junction maintenance;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0060729//intestinal epithelial structure maintenance;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:1903409//reactive oxygen species biosynthetic process	--
ENSG00000163374	19.275	20.477	19.855	19.329	18.825	22.752	1022.3	1062.58	781.78	724.6	853.93	861.47	YY1AP1	YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031011//Ino80 complex	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell population proliferation;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle"	--
ENSG00000163376	1.631	0.793	0.572	0.618	0.907	1.388	62	57	41	21	47	40	KBTBD8	kelch repeat and BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:30691]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0006513//protein monoubiquitination;GO:0014029//neural crest formation;GO:0014032//neural crest cell development	--
ENSG00000163377	0.125	0.065	0	0.058	0.205	0.089	3	3	0	2	8	3	TAFA4	TAFA chemokine like family member 4 [Source:HGNC Symbol;Acc:HGNC:21591]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0010469//regulation of signaling receptor activity;GO:0042391//regulation of membrane potential;GO:0042554//superoxide anion generation;GO:0048246//macrophage chemotaxis;GO:0051930//regulation of sensory perception of pain	--
ENSG00000163378	4.212	3.68	3.785	2.87	2.646	2.388	227	179	129	123	164	108	EOGT	EGF domain specific O-linked N-acetylglucosamine transferase [Source:HGNC Symbol;Acc:HGNC:28526]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K18134	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016262//protein N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0097363//protein O-GlcNAc transferase activity	GO:0006493//protein O-linked glycosylation;GO:0097370//protein O-GlcNAcylation via threonine	--
ENSG00000163380	0.059	0.029	0.013	0	0	0	6	3	1	0	0	0	LMOD3	leiomodin 3 [Source:HGNC Symbol;Acc:HGNC:6649]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0030016//myofibril;GO:0031430//M band;GO:0031672//A band	GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding	GO:0006936//muscle contraction;GO:0006941//striated muscle contraction;GO:0007015//actin filament organization;GO:0030239//myofibril assembly;GO:0030240//skeletal muscle thin filament assembly;GO:0045010//actin nucleation;GO:0048741//skeletal muscle fiber development;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0051694//pointed-end actin filament capping	--
ENSG00000163382	64.632	66.839	75.195	81.126	73.791	78.414	1499	1551	1295	1372	1432	1314	NAXE	NAD(P)HX epimerase [Source:HGNC Symbol;Acc:HGNC:18453]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005929//cilium;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0052856//NADHX epimerase activity;GO:0052857//NADPHX epimerase activity	GO:0002040//sprouting angiogenesis;GO:0006869//lipid transport;GO:0010874//regulation of cholesterol efflux;GO:0016525//negative regulation of angiogenesis;GO:0031580//membrane raft distribution;GO:0046496//nicotinamide nucleotide metabolic process	--
ENSG00000163389	7.174	8.026	7.106	7.367	5.847	6.307	522	587	367	348	350	330	POGLUT1	protein O-glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:22954]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K13667	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0012505//endomembrane system	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity;GO:0035252//UDP-xylosyltransferase activity;GO:0046527//glucosyltransferase activity;GO:0140561//EGF-domain serine glucosyltransferase activity;GO:0140562//EGF-domain serine xylosyltransferase activity	GO:0001756//somitogenesis;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007369//gastrulation;GO:0008593//regulation of Notch signaling pathway;GO:0010470//regulation of gastrulation;GO:0018242//protein O-linked glycosylation via serine;GO:0045747//positive regulation of Notch signaling pathway;GO:0048318//axial mesoderm development;GO:0048339//paraxial mesoderm development;GO:0060537//muscle tissue development;GO:0072359//circulatory system development	--
ENSG00000163393	1.506	1.466	1.512	1.494	2.292	1.817	147	134	109	108	189	129	SLC22A15	solute carrier family 22 member 15 [Source:HGNC Symbol;Acc:HGNC:20301]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0008150//biological_process;GO:0055085//transmembrane transport	--
ENSG00000163394	0	0	0	0	0	0	0	0	0	0	0	0	CCKAR	cholecystokinin A receptor [Source:HGNC Symbol;Acc:HGNC:1570]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Digestive system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04972//Pancreatic secretion;ko04911//Insulin secretion	K04194;K04194;K04194;K04194	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004951//cholecystokinin receptor activity;GO:0017046//peptide hormone binding	GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007409//axonogenesis;GO:0030900//forebrain development;GO:0038188//cholecystokinin signaling pathway;GO:0046883//regulation of hormone secretion	--
ENSG00000163395	0.25	0.319	0.169	0.812	0.51	0.313	53	65	27	116	83	54	IGFN1	immunoglobulin like and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24607]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0045202//synapse	GO:0005515//protein binding	GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly;GO:0008150//biological_process;GO:0010842//retina layer formation	--
ENSG00000163399	350.641	341.351	348.455	344.809	357.675	396.845	26265	25789	19358	19181	22743	21728	ATP1A1	ATPase Na+/K+ transporting subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:799]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030315//T-tubule;GO:0030424//axon;GO:0031090//organelle membrane;GO:0032991//protein-containing complex;GO:0036126//sperm flagellum;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0060342//photoreceptor inner segment membrane;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005391//P-type sodium:potassium-exchanging transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0016791//phosphatase activity;GO:0016887//ATP hydrolysis activity;GO:0030955//potassium ion binding;GO:0031402//sodium ion binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:1990239//steroid hormone binding	GO:0002026//regulation of the force of heart contraction;GO:0002028//regulation of sodium ion transport;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0008217//regulation of blood pressure;GO:0009410//response to xenobiotic stimulus;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0016311//dephosphorylation;GO:0030007//cellular potassium ion homeostasis;GO:0031947//negative regulation of glucocorticoid biosynthetic process;GO:0036376//sodium ion export across plasma membrane;GO:0045822//negative regulation of heart contraction;GO:0045823//positive regulation of heart contraction;GO:0045989//positive regulation of striated muscle contraction;GO:0055119//relaxation of cardiac muscle;GO:0071383//cellular response to steroid hormone stimulus;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086009//membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:1902600//proton transmembrane transport;GO:1903416//response to glycoside;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000163406	2.817	2.966	3.878	2.195	1.99	2.541	245	276	219	147	175	149	SLC15A2	solute carrier family 15 member 2 [Source:HGNC Symbol;Acc:HGNC:10921]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0044214//spanning component of plasma membrane;GO:0070062//extracellular exosome;GO:0089717//spanning component of membrane	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015333//peptide:proton symporter activity;GO:0022857//transmembrane transporter activity;GO:0035673//oligopeptide transmembrane transporter activity;GO:0071916//dipeptide transmembrane transporter activity	GO:0002376//immune system process;GO:0006811//ion transport;GO:0006857//oligopeptide transport;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0015835//peptidoglycan transport;GO:0042908//xenobiotic transport;GO:0042938//dipeptide transport;GO:0045087//innate immune response;GO:0055085//transmembrane transport;GO:0070293//renal absorption;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0140206//dipeptide import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902600//proton transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000163412	4.174	3.726	4.791	6.475	4.594	4.964	381.17	312	336.76	374.24	334	322.4	EIF4E3	eukaryotic translation initiation factor 4E family member 3 [Source:HGNC Symbol;Acc:HGNC:31837]	-	-	-	-	GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0016281//eukaryotic translation initiation factor 4F complex	GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation	--
ENSG00000163421	0.218	0.124	0.084	0.168	0.147	0.299	7	4	2	4	4	7	PROK2	prokineticin 2 [Source:HGNC Symbol;Acc:HGNC:18455]	-	-	-	-	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001935//endothelial cell proliferation;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0019233//sensory perception of pain;GO:0043066//negative regulation of apoptotic process;GO:0045987//positive regulation of smooth muscle contraction;GO:0048511//rhythmic process	--
ENSG00000163424	0	0	0	0	0	0	0	0	0	0	0	0	TEX55	testis expressed 55 [Source:HGNC Symbol;Acc:HGNC:26553]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000163428	11.611	7.374	8.805	8.105	8.266	9.28	1907	1217.29	1068	986	1147	1109	LRRC58	leucine rich repeat containing 58 [Source:HGNC Symbol;Acc:HGNC:26968]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163430	208.092	208.06	152.827	136.441	145.487	126.906	13675	14618	8343	7245	8701	6369	FSTL1	follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0030154//cell differentiation;GO:0030510//regulation of BMP signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043542//endothelial cell migration;GO:0045446//endothelial cell differentiation;GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000163431	6.21	5.851	5.186	3.63	4.975	5.725	505	475	312	219	338	336	LMOD1	leiomodin 1 [Source:HGNC Symbol;Acc:HGNC:6647]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0016020//membrane;GO:0030016//myofibril;GO:0030017//sarcomere	GO:0003779//actin binding;GO:0005523//tropomyosin binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0030239//myofibril assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0045010//actin nucleation;GO:0051694//pointed-end actin filament capping	--
ENSG00000163435	3.063	3.542	2.798	2.498	2.24	2.577	154	174	93	87	92	84	ELF3	E74 like ETS transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3318]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001824//blastocyst development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030855//epithelial cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060056//mammary gland involution"	ETS
ENSG00000163440	0	0	0	0	0	0	0	0	0	0	0	0	PDCL2	phosducin like 2 [Source:HGNC Symbol;Acc:HGNC:29524]	-	-	-	-	-	-	-	--
ENSG00000163444	26.054	25.288	25.219	27.207	23.628	26.255	1638	1598	1171	1267	1255	1201	TMEM183A	transmembrane protein 183A [Source:HGNC Symbol;Acc:HGNC:20173]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031647//regulation of protein stability	--
ENSG00000163449	2.072	2.863	1.647	1.199	1.555	1.805	112	78	55	61	90	71	TMEM169	transmembrane protein 169 [Source:HGNC Symbol;Acc:HGNC:25130]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000163453	407.519	431.654	422.155	473.621	473.544	471.216	12056.85	12836.72	9219	10379.75	11837.85	10141.94	IGFBP7	insulin like growth factor binding protein 7 [Source:HGNC Symbol;Acc:HGNC:5476]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding	GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007566//embryo implantation;GO:0008285//negative regulation of cell population proliferation;GO:0009408//response to heat;GO:0009966//regulation of signal transduction;GO:0014070//response to organic cyclic compound;GO:0032526//response to retinoic acid;GO:0032870//cellular response to hormone stimulus;GO:0050810//regulation of steroid biosynthetic process;GO:0051414//response to cortisol	--
ENSG00000163462	1.366	1.754	1.599	1.413	1.407	1.583	74	86	63	60	68	67	TRIM46	tripartite motif containing 46 [Source:HGNC Symbol;Acc:HGNC:19019]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030424//axon;GO:0042995//cell projection;GO:0043194//axon initial segment;GO:0044304//main axon;GO:0110165//cellular anatomical entity;GO:1904115//axon cytoplasm;GO:1990769//proximal neuron projection	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0001764//neuron migration;GO:0007409//axonogenesis;GO:0030517//negative regulation of axon extension;GO:0032880//regulation of protein localization;GO:0048490//anterograde synaptic vesicle transport;GO:0099612//protein localization to axon;GO:1901953//positive regulation of anterograde dense core granule transport	--
ENSG00000163463	51.407	49.29	56.665	66.17	54.312	64.45	557.67	536.55	454	531.91	497.95	508.71	KRTCAP2	keratinocyte associated protein 2 [Source:HGNC Symbol;Acc:HGNC:28942]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008047//enzyme activator activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0042543//protein N-linked glycosylation via arginine;GO:0050790//regulation of catalytic activity	--
ENSG00000163464	0	0	0	0	0	0	0	0	0	0	0	0	CXCR1	C-X-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:6026]	Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Transport and catabolism;Signal transduction;Immune system;Signaling molecules and interaction;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K04175;K04175;K04175;K04175;K04175;K04175	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0004918//interleukin-8 receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0019959//interleukin-8 binding	GO:0002407//dendritic cell chemotaxis;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0030593//neutrophil chemotaxis;GO:0031623//receptor internalization;GO:0038112//interleukin-8-mediated signaling pathway;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000163466	109.638	114.572	106.798	104.914	99.301	109.558	3164	3343	2288	2242	2419	2297	ARPC2	actin related protein 2/3 complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:705]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05758;K05758;K05758;K05758;K05758;K05758;K05758;K05758;K05758	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0035861//site of double-strand break;GO:0036195//muscle cell projection membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0010592//positive regulation of lamellipodium assembly;GO:0030041//actin filament polymerization;GO:0030833//regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0070358//actin polymerization-dependent cell motility;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000163467	0.241	0.11	0	0.508	0	0.139	3	1	0	4	0	1	TSACC	TSSK6 activating cochaperone [Source:HGNC Symbol;Acc:HGNC:30636]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0051087//chaperone binding	-	--
ENSG00000163468	117.715	119.254	124.824	118.798	112.239	116.303	4793	4896	3717	3573	3865	3451	CCT3	chaperonin containing TCP1 subunit 3 [Source:HGNC Symbol;Acc:HGNC:1616]	-	-	-	-	GO:0002199//zona pellucida receptor complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0046931//pore complex assembly;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000163472	2.791	2.453	2.801	2.537	3.125	3.115	114	102	94	70	120	103	TMEM79	transmembrane protein 79 [Source:HGNC Symbol;Acc:HGNC:28196]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002070//epithelial cell maturation;GO:0031069//hair follicle morphogenesis;GO:0042335//cuticle development;GO:0045055//regulated exocytosis;GO:0045684//positive regulation of epidermis development;GO:0061436//establishment of skin barrier;GO:0070268//cornification	--
ENSG00000163479	196.894	210.9	205.067	226.34	210.171	182.303	4513	4827	3437	3844	4065	3029	SSR2	signal sequence receptor subunit 2 [Source:HGNC Symbol;Acc:HGNC:11324]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13250	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006613//cotranslational protein targeting to membrane	--
ENSG00000163481	8.846	10.264	10.43	11.281	10.857	11.574	271	306	236	256	281	258	RNF25	ring finger protein 25 [Source:HGNC Symbol;Acc:HGNC:14662]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000163482	9.304	9.428	13.095	10.536	12.302	13.051	853	863	750	704	821	811	STK36	serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209]	Environmental Information Processing	Signal transduction	ko04341//Hedgehog signaling pathway - fly	K06228	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0001222//transcription corepressor binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0006468//protein phosphorylation;GO:0007224//smoothened signaling pathway;GO:0007228//positive regulation of hh target transcription factor activity;GO:0007420//brain development;GO:0009791//post-embryonic development;GO:0016310//phosphorylation;GO:0030030//cell projection organization;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0060271//cilium assembly	--
ENSG00000163485	2.262	2.173	1.101	1.796	1.323	1.55	74	72	48	51	48	52	ADORA1	adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Signal transduction;Substance dependence;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04071//Sphingolipid signaling pathway;ko05032//Morphine addiction;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K04265;K04265;K04265;K04265;K04265;K04265;K04265	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030425//dendrite;GO:0030673//axolemma;GO:0032279//asymmetric synapse;GO:0042734//presynaptic membrane;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048786//presynaptic active zone;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0110165//cellular anatomical entity	GO:0001609//G protein-coupled adenosine receptor activity;GO:0001664//G protein-coupled receptor binding;GO:0001883//purine nucleoside binding;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0032795//heterotrimeric G-protein binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0099582//neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration	"GO:0001659//temperature homeostasis;GO:0001666//response to hypoxia;GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0002674//negative regulation of acute inflammatory response;GO:0002686//negative regulation of leukocyte migration;GO:0002793//positive regulation of peptide secretion;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0003093//regulation of glomerular filtration;GO:0006612//protein targeting to membrane;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0010035//response to inorganic substance;GO:0014050//negative regulation of glutamate secretion;GO:0014074//response to purine-containing compound;GO:0016042//lipid catabolic process;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0032244//positive regulation of nucleoside transport;GO:0032900//negative regulation of neurotrophin production;GO:0035307//positive regulation of protein dephosphorylation;GO:0035814//negative regulation of renal sodium excretion;GO:0042311//vasodilation;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0042323//negative regulation of circadian sleep/wake cycle, non-REM sleep;GO:0043066//negative regulation of apoptotic process;GO:0043268//positive regulation of potassium ion transport;GO:0043410//positive regulation of MAPK cascade;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045776//negative regulation of blood pressure;GO:0045777//positive regulation of blood pressure;GO:0045822//negative regulation of heart contraction;GO:0046888//negative regulation of hormone secretion;GO:0050728//negative regulation of inflammatory response;GO:0050890//cognition;GO:0050896//response to stimulus;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050995//negative regulation of lipid catabolic process;GO:0050996//positive regulation of lipid catabolic process;GO:0051930//regulation of sensory perception of pain;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0055089//fatty acid homeostasis;GO:0055117//regulation of cardiac muscle contraction;GO:0060079//excitatory postsynaptic potential;GO:0060087//relaxation of vascular associated smooth muscle;GO:0070256//negative regulation of mucus secretion;GO:0070328//triglyceride homeostasis;GO:0086004//regulation of cardiac muscle cell contraction;GO:0097190//apoptotic signaling pathway;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:0110148//biomineralization;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1900453//negative regulation of long-term synaptic depression;GO:1901216//positive regulation of neuron death"	--
ENSG00000163491	0.763	0.527	0.194	0.148	0.726	0.294	36	24	13	6	20	6	NEK10	NIMA related kinase 10 [Source:HGNC Symbol;Acc:HGNC:18592]	-	-	-	-	GO:0005576//extracellular region;GO:1902911//protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0031954//positive regulation of protein autophosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0120197//mucociliary clearance;GO:1902749//regulation of cell cycle G2/M phase transition	--
ENSG00000163492	0.681	1.008	1.126	0.68	0.801	0.761	130	124	82	62	74	62	CCDC141	coiled-coil domain containing 141 [Source:HGNC Symbol;Acc:HGNC:26821]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0043005//neuron projection	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0021799//cerebral cortex radially oriented cell migration;GO:0051642//centrosome localization	--
ENSG00000163497	0	0	0	0	0	0	0	0	0	0	0	0	FEV	"FEV transcription factor, ETS family member [Source:HGNC Symbol;Acc:HGNC:18562]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09437	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0042551//neuron maturation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048665//neuron fate specification"	ETS
ENSG00000163499	0.068	0	0	0.072	0	0.094	1	0	0	1	0	1	CRYBA2	crystallin beta A2 [Source:HGNC Symbol;Acc:HGNC:2395]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0008150//biological_process	--
ENSG00000163501	0.019	0	0	0	0	0	1	0	0	0	0	0	IHH	Indian hedgehog signaling molecule [Source:HGNC Symbol;Acc:HGNC:5956]	Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction	ko05205//Proteoglycans in cancer;ko04340//Hedgehog signaling pathway	K11989;K11989	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031012//extracellular matrix	GO:0005113//patched binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0001763//morphogenesis of a branching structure;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003382//epithelial cell morphogenesis;GO:0003406//retinal pigment epithelium development;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0006029//proteoglycan metabolic process;GO:0006508//proteolysis;GO:0007224//smoothened signaling pathway;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0008284//positive regulation of cell population proliferation;GO:0009612//response to mechanical stimulus;GO:0009880//embryonic pattern specification;GO:0010468//regulation of gene expression;GO:0016539//intein-mediated protein splicing;GO:0016540//protein autoprocessing;GO:0030154//cell differentiation;GO:0030704//vitelline membrane formation;GO:0031016//pancreas development;GO:0032355//response to estradiol;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0035264//multicellular organism growth;GO:0035988//chondrocyte proliferation;GO:0040008//regulation of growth;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0045453//bone resorption;GO:0045596//negative regulation of cell differentiation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046639//negative regulation of alpha-beta T cell differentiation;GO:0048074//negative regulation of eye pigmentation;GO:0048469//cell maturation;GO:0048557//embryonic digestive tract morphogenesis;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048666//neuron development;GO:0048745//smooth muscle tissue development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0060135//maternal process involved in female pregnancy;GO:0060220//camera-type eye photoreceptor cell fate commitment;GO:0060323//head morphogenesis;GO:0061053//somite development;GO:0072498//embryonic skeletal joint development;GO:0090136//epithelial cell-cell adhesion;GO:0097421//liver regeneration	--
ENSG00000163507	0.795	0.893	0.764	0.506	0.872	0.652	51	54	35	26	44	29	CIP2A	cellular inhibitor of PP2A [Source:HGNC Symbol;Acc:HGNC:29302]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding	-	--
ENSG00000163508	0	0	0	0.02	0.027	0	0	0	0	1	1	0	EOMES	eomesodermin [Source:HGNC Symbol;Acc:HGNC:3372]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001706//endoderm formation;GO:0001707//mesoderm formation;GO:0001708//cell fate specification;GO:0001714//endodermal cell fate specification;GO:0001824//blastocyst development;GO:0001829//trophectodermal cell differentiation;GO:0002250//adaptive immune response;GO:0002302//CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007369//gastrulation;GO:0007420//brain development;GO:0007492//endoderm development;GO:0009653//anatomical structure morphogenesis;GO:0010002//cardioblast differentiation;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0021772//olfactory bulb development;GO:0021796//cerebral cortex regionalization;GO:0021895//cerebral cortex neuron differentiation;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048382//mesendoderm development;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060809//mesodermal to mesenchymal transition involved in gastrulation"	T-box
ENSG00000163510	3.701	2.511	2.27	1.074	2.032	2.651	232	171	101	52	112	129	CWC22	CWC22 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:29322]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome"	--
ENSG00000163512	18.405	17.28	15.876	11.747	12.597	16.978	920.1	918.66	595.35	451.8	554.46	609.35	AZI2	5-azacytidine induced 2 [Source:HGNC Symbol;Acc:HGNC:24002]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12651	GO:0005737//cytoplasm;GO:1902554//serine/threonine protein kinase complex	GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042110//T cell activation;GO:0044565//dendritic cell proliferation;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0097028//dendritic cell differentiation	--
ENSG00000163513	14.253	14.428	11.608	8.498	9.917	9.367	1342	1365	808	593	789	643	TGFBR2	transforming growth factor beta receptor 2 [Source:HGNC Symbol;Acc:HGNC:11773]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Signaling molecules and interaction;Cancer: overview;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Signal transduction;Cancer: specific types;Signal transduction;Endocrine system;Development and regeneration;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04659//Th17 cell differentiation;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko04520//Adherens junction	K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388;K04388	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0070021//transforming growth factor beta ligand-receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005026//transforming growth factor beta receptor activity, type II;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005539//glycosaminoglycan binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017002//activin-activated receptor activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0034714//type III transforming growth factor beta receptor binding;GO:0038023//signaling receptor activity;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0050431//transforming growth factor beta binding"	"GO:0001568//blood vessel development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001947//heart looping;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002088//lens development in camera-type eye;GO:0002651//positive regulation of tolerance induction to self antigen;GO:0002663//positive regulation of B cell tolerance induction;GO:0002666//positive regulation of T cell tolerance induction;GO:0003148//outflow tract septum morphogenesis;GO:0003149//membranous septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0003274//endocardial cushion fusion;GO:0003417//growth plate cartilage development;GO:0003430//growth plate cartilage chondrocyte growth;GO:0006468//protein phosphorylation;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007182//common-partner SMAD protein phosphorylation;GO:0007219//Notch signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007369//gastrulation;GO:0007420//brain development;GO:0007507//heart development;GO:0007566//embryo implantation;GO:0007568//aging;GO:0007584//response to nutrient;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009749//response to glucose;GO:0009887//animal organ morphogenesis;GO:0010033//response to organic substance;GO:0010468//regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014070//response to organic cyclic compound;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0031100//animal organ regeneration;GO:0032147//activation of protein kinase activity;GO:0032924//activin receptor signaling pathway;GO:0035162//embryonic hemopoiesis;GO:0040008//regulation of growth;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0043011//myeloid dendritic cell differentiation;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0043627//response to estrogen;GO:0045766//positive regulation of angiogenesis;GO:0048545//response to steroid hormone;GO:0048565//digestive tract development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0051138//positive regulation of NK T cell differentiation;GO:0051216//cartilage development;GO:0051239//regulation of multicellular organismal process;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060412//ventricular septum morphogenesis;GO:0060425//lung morphogenesis;GO:0060433//bronchus development;GO:0060434//bronchus morphogenesis;GO:0060439//trachea morphogenesis;GO:0060440//trachea formation;GO:0060443//mammary gland morphogenesis;GO:0060463//lung lobe morphogenesis;GO:0062009//secondary palate development;GO:0070723//response to cholesterol;GO:0071363//cellular response to growth factor stimulus;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1905317//inferior endocardial cushion morphogenesis;GO:1990086//lens fiber cell apoptotic process;GO:1990428//miRNA transport;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000163515	0	0	0	0	0	0	0	0	0	0	0	0	RETNLB	resistin like beta [Source:HGNC Symbol;Acc:HGNC:20388]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0050673//epithelial cell proliferation	--
ENSG00000163516	7.972	7.665	8.327	8.191	7.889	8.713	377	405	324	308	340	334	ANKZF1	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0070301//cellular response to hydrogen peroxide	--
ENSG00000163517	24.166	28.759	26.73	31.833	29.484	27.271	1032	1078	811	904	988	846	HDAC11	histone deacetylase 11 [Source:HGNC Symbol;Acc:HGNC:19086]	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11418;K11418;K11418	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005886//plasma membrane	GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0140297//DNA-binding transcription factor binding	GO:0006325//chromatin organization;GO:0014003//oligodendrocyte development;GO:0016575//histone deacetylation	--
ENSG00000163518	0	0	0	0	0	0	0	0	0	0	0	0	FCRL4	Fc receptor like 4 [Source:HGNC Symbol;Acc:HGNC:18507]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000163519	0	0	0	0	0	0	0	0	0	0	0	0	TRAT1	T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0042101//T cell receptor complex;GO:0072686//mitotic spindle	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding	GO:0001920//negative regulation of receptor recycling;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051051//negative regulation of transport	--
ENSG00000163520	65.098	68.803	50.648	24.696	33.682	34.941	5606	5951	3224	1577	2454	2189	FBLN2	fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:1903561//extracellular vesicle	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0050840//extracellular matrix binding	GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization	--
ENSG00000163521	10.896	14.304	12.77	8.76	9.09	9.033	526	599	389	283	343	302	GLB1L	galactosidase beta 1 like [Source:HGNC Symbol;Acc:HGNC:28129]	-	-	-	-	GO:0005576//extracellular region;GO:0005773//vacuole	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004565//beta-galactosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000163527	89.567	82.406	73.129	67.606	68.486	67.39	7630	7056	4601	4266	4929	4177	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B [Source:HGNC Symbol;Acc:HGNC:30611]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K07151;K07151;K07151;K07151	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0034998//oligosaccharyltransferase I complex	GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006516//glycoprotein catabolic process;GO:0006986//response to unfolded protein;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043686//co-translational protein modification;GO:0043687//post-translational protein modification	--
ENSG00000163528	9.546	7.372	9.67	9.292	7.05	10.218	287	223	213	209	179	224	CHCHD4	coiled-coil-helix-coiled-coil-helix domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26467]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity	GO:0015031//protein transport;GO:0018171//peptidyl-cysteine oxidation;GO:0022417//protein maturation by protein folding;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0045041//protein import into mitochondrial intermembrane space;GO:0051084//'de novo' posttranslational protein folding	--
ENSG00000163530	0	0	0	0	0	0	0	0	0	0	0	0	DPPA2	developmental pluripotency associated 2 [Source:HGNC Symbol;Acc:HGNC:19197]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0048731//system development	--
ENSG00000163531	6.487	7.745	3.067	2.782	3.411	2.163	548	721	231	176	255	133	NFASC	neurofascin [Source:HGNC Symbol;Acc:HGNC:29866]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06757	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0033010//paranodal junction;GO:0033268//node of Ranvier;GO:0043194//axon initial segment;GO:0097454//Schwann cell microvillus;GO:0101003//ficolin-1-rich granule membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007422//peripheral nervous system development;GO:0019226//transmission of nerve impulse;GO:0042552//myelination;GO:0050808//synapse organization;GO:0072659//protein localization to plasma membrane;GO:0098609//cell-cell adhesion	--
ENSG00000163534	0	0	0	0	0	0	0	0	0	0	0	0	FCRL1	Fc receptor like 1 [Source:HGNC Symbol;Acc:HGNC:18509]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0015026//coreceptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0042113//B cell activation	--
ENSG00000163535	1.067	0.804	0.672	0.16	0.357	0.281	58	62	25	11	28	19	SGO2	shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0030892//mitotic cohesin complex"	GO:0005515//protein binding	"GO:0000070//mitotic sister chromatid segregation;GO:0006996//organelle organization;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0045143//homologous chromosome segregation;GO:0051177//meiotic sister chromatid cohesion;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051754//meiotic sister chromatid cohesion, centromeric"	--
ENSG00000163536	7.774	5.51	8.097	7.836	6.808	8.435	226	179	199	195	187	175	SERPINI1	serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0060205//cytoplasmic vesicle lumen;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0010976//positive regulation of neuron projection development;GO:0030155//regulation of cell adhesion	--
ENSG00000163539	17.658	13.975	13.571	10.924	11.52	12.771	1631	1411	1023	759	1035	860	CLASP2	cytoplasmic linker associated protein 2 [Source:HGNC Symbol;Acc:HGNC:17078]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043232//intracellular non-membrane-bounded organelle;GO:0044295//axonal growth cone;GO:0045180//basal cortex;GO:0072686//mitotic spindle;GO:1903754//cortical microtubule plus-end"	GO:0002162//dystroglycan binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0051010//microtubule plus-end binding;GO:0051015//actin filament binding;GO:1990782//protein tyrosine kinase binding	"GO:0000226//microtubule cytoskeleton organization;GO:0006903//vesicle targeting;GO:0007020//microtubule nucleation;GO:0007026//negative regulation of microtubule depolymerization;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007163//establishment or maintenance of cell polarity;GO:0010458//exit from mitosis;GO:0010470//regulation of gastrulation;GO:0010634//positive regulation of epithelial cell migration;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0030516//regulation of axon extension;GO:0031023//microtubule organizing center organization;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031113//regulation of microtubule polymerization;GO:0032886//regulation of microtubule-based process;GO:0032956//regulation of actin cytoskeleton organization;GO:0034453//microtubule anchoring;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0040001//establishment of mitotic spindle localization;GO:0045921//positive regulation of exocytosis;GO:0051128//regulation of cellular component organization;GO:0051301//cell division;GO:0051497//negative regulation of stress fiber assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0072659//protein localization to plasma membrane;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0090307//mitotic spindle assembly;GO:1903690//negative regulation of wound healing, spreading of epidermal cells;GO:1904261//positive regulation of basement membrane assembly involved in embryonic body morphogenesis"	--
ENSG00000163541	45.735	46.669	47.39	51.351	44.336	43.304	1205	1236	922	1002	987	830	SUCLG1	succinate-CoA ligase GDP/ADP-forming subunit alpha [Source:HGNC Symbol;Acc:HGNC:11449]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00640//Propanoate metabolism;ko00020//Citrate cycle (TCA cycle)	K01899;K01899;K01899;K01899	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0009361//succinate-CoA ligase complex (ADP-forming);GO:0045244//succinate-CoA ligase complex (GDP-forming)	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0004776//succinate-CoA ligase (GDP-forming) activity;GO:0005515//protein binding;GO:0016874//ligase activity	GO:0006099//tricarboxylic acid cycle;GO:1901289//succinyl-CoA catabolic process	--
ENSG00000163545	3.739	3.465	4.562	5.24	5.621	5.608	263	245	237	273	334	287	NUAK2	NUAK family kinase 2 [Source:HGNC Symbol;Acc:HGNC:29558]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0016310//phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0043066//negative regulation of apoptotic process	--
ENSG00000163554	0	0	0	0.016	0	0	0	0	0	2	0	0	SPTA1	"spectrin alpha, erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11272]"	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K06114	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0009898//cytoplasmic side of plasma membrane;GO:0014731//spectrin-associated cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030863//cortical cytoskeleton;GO:0030864//cortical actin cytoskeleton;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0032437//cuticular plate;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0002260//lymphocyte homeostasis;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007009//plasma membrane organization;GO:0007015//actin filament organization;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0030097//hemopoiesis;GO:0032092//positive regulation of protein binding;GO:0042102//positive regulation of T cell proliferation;GO:0051693//actin filament capping	--
ENSG00000163558	11.187	10.217	9.858	7.631	8.162	10.996	1134	1041	738	573	699	811	PRKCI	protein kinase C iota [Source:HGNC Symbol;Acc:HGNC:9404]	Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems	Infectious disease: viral;Transport and catabolism;Signal transduction;Cellular community - eukaryotes;Signal transduction;Endocrine system;Immune system	ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04910//Insulin signaling pathway;ko04611//Platelet activation	K06069;K06069;K06069;K06069;K06069;K06069;K06069	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031252//cell leading edge;GO:0043220//Schmidt-Lanterman incisure;GO:0045171//intercellular bridge;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0070160//tight junction;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0120157//PAR polarity complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006612//protein targeting to membrane;GO:0007010//cytoskeleton organization;GO:0007015//actin filament organization;GO:0010976//positive regulation of neuron projection development;GO:0016192//vesicle-mediated transport;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0032869//cellular response to insulin stimulus;GO:0034351//negative regulation of glial cell apoptotic process;GO:0034613//cellular protein localization;GO:0035089//establishment of apical/basal cell polarity;GO:0035556//intracellular signal transduction;GO:0042462//eye photoreceptor cell development;GO:0043066//negative regulation of apoptotic process;GO:0043434//response to peptide hormone;GO:0043524//negative regulation of neuron apoptotic process;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045216//cell-cell junction organization;GO:0045747//positive regulation of Notch signaling pathway;GO:0046326//positive regulation of glucose import;GO:0046903//secretion;GO:0048194//Golgi vesicle budding;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060252//positive regulation of glial cell proliferation;GO:0061024//membrane organization;GO:0070555//response to interleukin-1;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000163563	6.602	5.926	4.603	1.517	0.665	1.39	235	212	121	40	20	36	MNDA	myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding	GO:0002218//activation of innate immune response;GO:0006968//cellular defense response;GO:0006974//cellular response to DNA damage stimulus;GO:0030889//negative regulation of B cell proliferation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0035458//cellular response to interferon-beta;GO:0043065//positive regulation of apoptotic process;GO:0050853//B cell receptor signaling pathway	--
ENSG00000163564	0	0	0	0	0	0	0	0	0	0	0	0	PYHIN1	pyrin and HIN domain family member 1 [Source:HGNC Symbol;Acc:HGNC:28894]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0003690//double-stranded DNA binding;GO:0031625//ubiquitin protein ligase binding	"GO:0002218//activation of innate immune response;GO:0007049//cell cycle;GO:0031648//protein destabilization;GO:0032731//positive regulation of interleukin-1 beta production;GO:0035457//cellular response to interferon-alpha;GO:0035458//cellular response to interferon-beta;GO:0043388//positive regulation of DNA binding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:1900182//positive regulation of protein localization to nucleus;GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000163565	3.308	3.074	2.072	3.161	2.561	2.412	150	148	82	108	98	92	IFI16	interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20914	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001819//positive regulation of cytokine production;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0010506//regulation of autophagy;GO:0030099//myeloid cell differentiation;GO:0030224//monocyte differentiation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0035458//cellular response to interferon-beta;GO:0040029//regulation of gene expression, epigenetic;GO:0042149//cellular response to glucose starvation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043392//negative regulation of DNA binding;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045824//negative regulation of innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0071479//cellular response to ionizing radiation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0097202//activation of cysteine-type endopeptidase activity;GO:2000117//negative regulation of cysteine-type endopeptidase activity"	--
ENSG00000163568	0	0.199	0	0	0.041	0.071	0	3	0	0	1	2	AIM2	absent in melanoma 2 [Source:HGNC Symbol;Acc:HGNC:357]	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04621//NOD-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12966;K12966	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0097169//AIM2 inflammasome complex	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002218//activation of innate immune response;GO:0002221//pattern recognition receptor signaling pathway;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032731//positive regulation of interleukin-1 beta production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035458//cellular response to interferon-beta;GO:0044546//NLRP3 inflammasome complex assembly;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0070269//pyroptosis;GO:0071466//cellular response to xenobiotic stimulus;GO:1904270//pyroptosome complex assembly;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000163576	0.256	0.271	0.227	1.132	0.481	0.478	10	11	7	17	11	7	EFHB	EF-hand domain family member B [Source:HGNC Symbol;Acc:HGNC:26330]	-	-	-	-	GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061891//calcium ion sensor activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0032091//negative regulation of protein binding;GO:0070884//regulation of calcineurin-NFAT signaling cascade;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000163577	4.994	4.547	2.916	2.351	1.813	5.71	266	229	109	121	142	168	EIF5A2	eukaryotic translation initiation factor 5A2 [Source:HGNC Symbol;Acc:HGNC:3301]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0007283//spermatogenesis;GO:0010509//polyamine homeostasis;GO:0015031//protein transport;GO:0045901//positive regulation of translational elongation;GO:0045905//positive regulation of translational termination;GO:0051028//mRNA transport	--
ENSG00000163581	0	0	0	0	0.018	0	0	0	0	0	1	0	SLC2A2	solute carrier family 2 member 2 [Source:HGNC Symbol;Acc:HGNC:11006]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: overview;Endocrine and metabolic disease;Digestive system;Endocrine and metabolic disease	ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04911//Insulin secretion;ko04917//Prolactin signaling pathway;ko05230//Central carbon metabolism in cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04950//Maturity onset diabetes of the young	K07593;K07593;K07593;K07593;K07593;K07593;K07593;K07593	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005353//fructose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0005975//carbohydrate metabolic process;GO:0008643//carbohydrate transport;GO:0015749//monosaccharide transmembrane transport;GO:0015755//fructose transmembrane transport;GO:0046323//glucose import;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:1904659//glucose transmembrane transport	--
ENSG00000163584	6.004	7.203	10.164	7.638	6.627	11.604	90	110	103	82	78	113	RPL22L1	ribosomal protein L22 like 1 [Source:HGNC Symbol;Acc:HGNC:27610]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02891;K02891	GO:0005737//cytoplasm;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000163586	0	0	0	0	0	0	0	0	0	0	0	0	FABP1	fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555]	Human Diseases;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine system;Digestive system	ko04936//Alcoholic liver disease;ko03320//PPAR signaling pathway;ko04975//Fat digestion and absorption	K08750;K08750;K08750	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0045179//apical cortex;GO:0070062//extracellular exosome	GO:0003682//chromatin binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016209//antioxidant activity;GO:0032052//bile acid binding;GO:0070538//oleic acid binding;GO:1901363//heterocyclic compound binding	GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050892//intestinal absorption;GO:0051345//positive regulation of hydrolase activity;GO:0070301//cellular response to hydrogen peroxide;GO:0071456//cellular response to hypoxia;GO:0098869//cellular oxidant detoxification	--
ENSG00000163590	3.406	3.338	3.717	2.741	3.651	2.496	602	502	380	328	384	304	PPM1L	"protein phosphatase, Mg2+/Mn2+ dependent 1L [Source:HGNC Symbol;Acc:HGNC:16381]"	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0006470//protein dephosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030148//sphingolipid biosynthetic process	--
ENSG00000163596	3.331	2.255	1.642	1.341	2.615	2.228	219	138	99	66	118	113	ICA1L	islet cell autoantigen 1 like [Source:HGNC Symbol;Acc:HGNC:14442]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0051049//regulation of transport	--
ENSG00000163599	0	0	0	0	0	0	0	0	0	0	0	0	CTLA4	cytotoxic T-lymphocyte associated protein 4 [Source:HGNC Symbol;Acc:HGNC:2505]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems	Immune disease;Signaling molecules and interaction;Immune disease;Immune system	ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05320//Autoimmune thyroid disease;ko04660//T cell receptor signaling pathway	K06538;K06538;K06538;K06538	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0098636//protein complex involved in cell adhesion	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0030889//negative regulation of B cell proliferation;GO:0042129//regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0050777//negative regulation of immune response;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway	--
ENSG00000163600	0	0	0	0	0	0	0	0	0	0	0	0	ICOS	inducible T cell costimulator [Source:HGNC Symbol;Acc:HGNC:5351]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Immune disease;Immune system;Immune system	ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko04660//T cell receptor signaling pathway	K06713;K06713;K06713;K06713	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002517//T cell tolerance induction;GO:0006955//immune response;GO:0031295//T cell costimulation;GO:0098609//cell-cell adhesion	--
ENSG00000163602	8.74	7.346	8.586	6.053	6.944	7.687	1308	1105	949	671	878	837	RYBP	RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031519//PcG protein complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007275//multicellular organism development;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035518//histone H2A monoubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000163605	17.576	13.393	13.094	10.452	11.814	16.087	1598	1261	970	796	901	1061	PPP4R2	protein phosphatase 4 regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:18296]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030289//protein phosphatase 4 complex	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0030674//protein-macromolecule adaptor activity	GO:0006397//mRNA processing;GO:0006464//cellular protein modification process;GO:0006470//protein dephosphorylation;GO:0008380//RNA splicing;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0016576//histone dephosphorylation;GO:0033128//negative regulation of histone phosphorylation;GO:0050790//regulation of catalytic activity;GO:2000779//regulation of double-strand break repair	--
ENSG00000163606	0	0	0	0	0	0	0	0	0	0	0	0	CD200R1	CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235]	Human Diseases	Infectious disease: viral	ko05167//Kaposi sarcoma-associated herpesvirus infection	K21668	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005515//protein binding;GO:0019763//immunoglobulin receptor activity;GO:0038023//signaling receptor activity;GO:0140081//glycosylated region protein binding	GO:0007165//signal transduction;GO:0032715//negative regulation of interleukin-6 production;GO:0034113//heterotypic cell-cell adhesion;GO:0035556//intracellular signal transduction;GO:0038093//Fc receptor signaling pathway;GO:0150077//regulation of neuroinflammatory response;GO:0150079//negative regulation of neuroinflammatory response;GO:1901215//negative regulation of neuron death;GO:1905522//negative regulation of macrophage migration;GO:2000405//negative regulation of T cell migration	--
ENSG00000163607	4.645	3.427	3.024	4.532	4.073	4.07	157	127	85	96	129	105	GTPBP8	GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007]	-	-	-	-	GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0046872//metal ion binding	-	--
ENSG00000163608	8.745	7.742	7.058	6.55	7.88	8.422	601	536	346	332	405	373	NEPRO	nucleolus and neural progenitor protein [Source:HGNC Symbol;Acc:HGNC:24496]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	-	GO:0045665//negative regulation of neuron differentiation;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000163611	2.233	1.997	2.417	2.256	1.786	2.43	230.71	175.69	104.48	110.17	102.34	107.11	SPICE1	spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0046599//regulation of centriole replication;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0090307//mitotic spindle assembly	--
ENSG00000163617	2.343	1.534	1.408	1.118	1.339	1.1	144	113	82	59	79	52	CCDC191	coiled-coil domain containing 191 [Source:HGNC Symbol;Acc:HGNC:29272]	-	-	-	-	-	-	-	--
ENSG00000163618	0.439	0.678	0.37	0.906	1.7	1.288	49	67	24	70	106	63	CADPS	calcium dependent secretion activator [Source:HGNC Symbol;Acc:HGNC:1426]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099012//neuronal dense core vesicle membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding	GO:0006887//exocytosis;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0045921//positive regulation of exocytosis;GO:1990504//dense core granule exocytosis	--
ENSG00000163623	0	0.014	0	0	0	0	0	1	0	0	0	0	NKX6-1	NK6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7839]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08030	GO:0000785//chromatin;GO:0005634//nucleus;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0003309//type B pancreatic cell differentiation;GO:0003323//type B pancreatic cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007224//smoothened signaling pathway;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009887//animal organ morphogenesis;GO:0021953//central nervous system neuron differentiation;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030516//regulation of axon extension;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0032024//positive regulation of insulin secretion;GO:0035094//response to nicotine;GO:0044342//type B pancreatic cell proliferation;GO:0045666//positive regulation of neuron differentiation;GO:0045686//negative regulation of glial cell differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048709//oligodendrocyte differentiation;GO:0050796//regulation of insulin secretion;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051594//detection of glucose;GO:0071345//cellular response to cytokine stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0072560//type B pancreatic cell maturation;GO:2000078//positive regulation of type B pancreatic cell development;GO:2001222//regulation of neuron migration"	Homeobox
ENSG00000163624	4.778	3.985	4.014	3.837	4.026	4.521	427	358	265	254	304	294	CDS1	CDP-diacylglycerol synthase 1 [Source:HGNC Symbol;Acc:HGNC:1800]	Metabolism;Metabolism;Environmental Information Processing	Global and overview maps;Lipid metabolism;Signal transduction	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system	K00981;K00981;K00981	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0004605//phosphatidate cytidylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016779//nucleotidyltransferase activity"	GO:0006629//lipid metabolic process;GO:0006657//CDP-choline pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0007602//phototransduction;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0045600//positive regulation of fat cell differentiation;GO:0140042//lipid droplet formation	--
ENSG00000163625	13.728	12.209	11.395	7.946	11.267	11.382	3307	2883	2121	1542	2132	1825	WDFY3	WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016234//inclusion body;GO:0016605//PML body;GO:0019898//extrinsic component of membrane;GO:0030424//axon;GO:0031965//nuclear membrane;GO:0034274//Atg12-Atg5-Atg16 complex;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043226//organelle;GO:0097635//extrinsic component of autophagosome membrane	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0008289//lipid binding;GO:0046872//metal ion binding	GO:0006914//autophagy;GO:0035973//aggrephagy	--
ENSG00000163626	6.571	5.003	5.849	5.209	4.437	5.851	361	322	292	214	231	289	COX18	cytochrome c oxidase assembly factor COX18 [Source:HGNC Symbol;Acc:HGNC:26801]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K17797	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0032977//membrane insertase activity	GO:0008535//respiratory chain complex IV assembly;GO:0032979//protein insertion into mitochondrial inner membrane from matrix;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0051204//protein insertion into mitochondrial membrane;GO:0051205//protein insertion into membrane;GO:0090150//establishment of protein localization to membrane	--
ENSG00000163629	21.199	15.423	15.227	10.273	11.445	14.092	3627	2683.99	1951	1305	1652	1774	PTPN13	protein tyrosine phosphatase non-receptor type 13 [Source:HGNC Symbol;Acc:HGNC:9646]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K02374	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0031047//gene silencing by RNA;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000163630	0.162	0.22	0.207	0.438	0.263	0.498	6	7	8	17	11	19	SYNPR	synaptoporin [Source:HGNC Symbol;Acc:HGNC:16507]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005515//protein binding	-	--
ENSG00000163631	0	0	0	0	0.04	0	0	0	0	0	1	0	ALB	albumin [Source:HGNC Symbol;Acc:HGNC:399]	Organismal Systems	Endocrine system	ko04918//Thyroid hormone synthesis	K16141	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0031093//platelet alpha granule lumen;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003677//DNA binding;GO:0005504//fatty acid binding;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0015643//toxic substance binding;GO:0016209//antioxidant activity;GO:0019825//oxygen binding;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0140272//exogenous protein binding;GO:1903981//enterobactin binding	GO:0001895//retina homeostasis;GO:0009267//cellular response to starvation;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0051659//maintenance of mitochondrion location;GO:0098869//cellular oxidant detoxification	--
ENSG00000163632	0.131	0	0	0	0	0	2	0	0	0	0	0	C3orf49	chromosome 3 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:25190]	-	-	-	-	-	-	-	--
ENSG00000163633	0.126	0.17	0.236	0.209	0.332	0	2	2	3.34	3.79	4	0	C4orf36	chromosome 4 open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:28386]	-	-	-	-	-	-	-	--
ENSG00000163634	17.421	16.812	16.596	17.54	15.046	15.751	321	312	226	232	235	210	THOC7	THO complex 7 [Source:HGNC Symbol;Acc:HGNC:29874]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K13176	"GO:0000346//transcription export complex;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0046784//viral mRNA export from host cell nucleus;GO:0051028//mRNA transport	--
ENSG00000163635	4.87	4.743	4.626	4.162	4.613	5.404	565	524	410	363	472	457	ATXN7	ataxin 7 [Source:HGNC Symbol;Acc:HGNC:10560]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016363//nuclear matrix;GO:0033276//transcription factor TFTC complex	GO:0005515//protein binding	"GO:0000226//microtubule cytoskeleton organization;GO:0006282//regulation of DNA repair;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006997//nucleus organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0007601//visual perception;GO:0016578//histone deubiquitination;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000163636	29.83	30.033	25.695	27.048	25.844	32.016	853	850	539	569	615	663	PSMD6	"proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03037;K03037;K03037;K03037;K03037;K03037;K03037;K03037;K03037	GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0022624//proteasome accessory complex;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000163637	2.767	2.797	3.378	2.73	3.496	3.124	459	465	317	337	493	382	PRICKLE2	prickle planar cell polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:20340]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04511	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0060071//Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000163638	1.768	1.42	1.738	0.723	0.809	1.369	230	217	157	80	104	124	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:HGNC Symbol;Acc:HGNC:13202]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0003179//heart valve morphogenesis;GO:0003229//ventricular cardiac muscle tissue development;GO:0006508//proteolysis;GO:0006516//glycoprotein catabolic process;GO:0007275//multicellular organism development;GO:0009617//response to bacterium;GO:0010596//negative regulation of endothelial cell migration;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030198//extracellular matrix organization;GO:0035909//aorta morphogenesis;GO:0045636//positive regulation of melanocyte differentiation;GO:0048070//regulation of developmental pigmentation;GO:0090673//endothelial cell-matrix adhesion;GO:1903671//negative regulation of sprouting angiogenesis	--
ENSG00000163644	3.297	3.929	2.394	1.861	2.238	2.169	253	288	159	139	195	170	PPM1K	"protein phosphatase, Mg2+/Mn2+ dependent 1K [Source:HGNC Symbol;Acc:HGNC:25415]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation	--
ENSG00000163645	0.055	0.047	0	0	0	0	2	2	0	0	0	0	ERICH6	glutamate rich 6 [Source:HGNC Symbol;Acc:HGNC:28602]	-	-	-	-	-	-	-	--
ENSG00000163646	0.023	0.085	0	0	0	0	1	3	0	0	0	0	CLRN1	clarin 1 [Source:HGNC Symbol;Acc:HGNC:12605]	-	-	-	-	GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030140//trans-Golgi network transport vesicle;GO:0032420//stereocilium;GO:0045178//basal part of cell	GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0010592//positive regulation of lamellipodium assembly;GO:0045494//photoreceptor cell maintenance;GO:0048870//cell motility;GO:0050885//neuromuscular process controlling balance;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0060088//auditory receptor cell stereocilium organization;GO:0060117//auditory receptor cell development	--
ENSG00000163655	53.223	47.422	52.921	49.468	50.94	49.415	3775	3341	2786	2478	3011	2539	GMPS	guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes	K01951;K01951;K01951	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003921//GMP synthase activity;GO:0003922//GMP synthase (glutamine-hydrolyzing) activity;GO:0005524//ATP binding;GO:0016462//pyrophosphatase activity;GO:0016874//ligase activity	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0046037//GMP metabolic process	--
ENSG00000163659	17.669	16.908	15.442	13.291	13.315	13.925	1262	1160	779	679	779	695	TIPARP	TCDD inducible poly(ADP-ribose) polymerase [Source:HGNC Symbol;Acc:HGNC:23696]	-	-	-	-	GO:0005634//nucleus	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding;GO:1990404//protein ADP-ribosylase activity	GO:0001570//vasculogenesis;GO:0001822//kidney development;GO:0006471//protein ADP-ribosylation;GO:0006807//nitrogen compound metabolic process;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0008585//female gonad development;GO:0009791//post-embryonic development;GO:0010629//negative regulation of gene expression;GO:0030097//hemopoiesis;GO:0045732//positive regulation of protein catabolic process;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0048745//smooth muscle tissue development;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0070213//protein auto-ADP-ribosylation;GO:0071407//cellular response to organic cyclic compound;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000163660	14.105	9.838	13.62	9.092	10.955	14.347	646	461	407	309	430	495	CCNL1	cyclin L1 [Source:HGNC Symbol;Acc:HGNC:20569]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006396//RNA processing;GO:0042981//regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0046605//regulation of centrosome cycle;GO:0051726//regulation of cell cycle"	--
ENSG00000163661	17.427	18.05	6.271	17.101	21.929	23.212	681	709	181	495	724	660	PTX3	pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	GO:0001849//complement component C1q complex binding;GO:0001872//(1->3)-beta-D-glucan binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046790//virion binding	GO:0001550//ovarian cumulus expansion;GO:0001878//response to yeast;GO:0006954//inflammatory response;GO:0008228//opsonization;GO:0030198//extracellular matrix organization;GO:0044793//negative regulation by host of viral process;GO:0044869//negative regulation by host of viral exo-alpha-sialidase activity;GO:0044871//negative regulation by host of viral glycoprotein metabolic process;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0046597//negative regulation of viral entry into host cell;GO:0050766//positive regulation of phagocytosis;GO:1903016//negative regulation of exo-alpha-sialidase activity;GO:1903019//negative regulation of glycoprotein metabolic process	--
ENSG00000163666	0.429	0.501	0.717	0.15	0.398	0.346	7	9	10	3	6	5	HESX1	HESX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4877]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09354	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0008406//gonad development;GO:0010467//gene expression;GO:0016055//Wnt signaling pathway;GO:0019827//stem cell population maintenance;GO:0021983//pituitary gland development;GO:0030878//thyroid gland development;GO:0030900//forebrain development;GO:0030916//otic vesicle formation;GO:0035264//multicellular organism growth;GO:0043010//camera-type eye development;GO:0043584//nose development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0048853//forebrain morphogenesis;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0048863//stem cell differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:0071276//cellular response to cadmium ion"	Homeobox
ENSG00000163673	0.009	0.027	0	0.049	0.011	0	1	3	0	4	1	0	DCLK3	doublecortin like kinase 3 [Source:HGNC Symbol;Acc:HGNC:19005]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000163681	11.155	10.992	7.491	6.029	9.495	8.667	961	826	525	419	640	572	SLMAP	sarcolemma associated protein [Source:HGNC Symbol;Acc:HGNC:16643]	-	-	-	-	GO:0005737//cytoplasm;GO:0005790//smooth endoplasmic reticulum;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0006936//muscle contraction;GO:0072659//protein localization to plasma membrane;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:1902305//regulation of sodium ion transmembrane transport;GO:1905150//regulation of voltage-gated sodium channel activity	--
ENSG00000163682	523.847	544.381	518.253	543.576	446.247	441.719	8036	8365	5888	6160	5766	4949	RPL9	ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:10369]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02940;K02940	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000163683	14.669	15.292	12.64	14.391	11.729	14.774	1308	1285	904	860	815	855	SMIM14	small integral membrane protein 14 [Source:HGNC Symbol;Acc:HGNC:27321]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001835//blastocyst hatching	--
ENSG00000163684	2.589	1.478	0.929	1.995	2.477	2.804	274.34	176.22	113.62	150.76	219.49	199.07	RPP14	ribonuclease P/MRP subunit p14 [Source:HGNC Symbol;Acc:HGNC:30327]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030677//ribonuclease P complex;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000163686	8.371	8.256	8.727	9.149	8.07	11.229	394	383	308	323	325	386	ABHD6	"abhydrolase domain containing 6, acylglycerol lipase [Source:HGNC Symbol;Acc:HGNC:21398]"	Organismal Systems	Nervous system	ko04723//Retrograde endocannabinoid signaling	K13700	GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0031966//mitochondrial membrane;GO:0032281//AMPA glutamate receptor complex;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0003824//catalytic activity;GO:0004620//phospholipase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity	GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0030336//negative regulation of cell migration;GO:0046464//acylglycerol catabolic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0052651//monoacylglycerol catabolic process;GO:0060292//long-term synaptic depression;GO:0120163//negative regulation of cold-induced thermogenesis;GO:2000124//regulation of endocannabinoid signaling pathway;GO:2001311//lysobisphosphatidic acid metabolic process	--
ENSG00000163687	0	0	0	0	0	0	0	0	0	0	0	0	DNASE1L3	deoxyribonuclease 1 like 3 [Source:HGNC Symbol;Acc:HGNC:2959]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004530//deoxyribonuclease I activity;GO:0004536//deoxyribonuclease activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0002283//neutrophil activation involved in immune response;GO:0002673//regulation of acute inflammatory response;GO:0006259//DNA metabolic process;GO:0006308//DNA catabolic process;GO:0006309//apoptotic DNA fragmentation;GO:0006915//apoptotic process;GO:0010623//programmed cell death involved in cell development;GO:0012501//programmed cell death;GO:0070948//regulation of neutrophil mediated cytotoxicity;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000163689	0.836	0.248	0.262	0.65	0.373	0.293	40	15	12	17	18	14	CFAP20DC	CFAP20 domain containing [Source:HGNC Symbol;Acc:HGNC:24763]	-	-	-	-	-	-	-	--
ENSG00000163694	42.493	40.302	41.925	36.327	43.548	42.875	3447	3107	2566	2127	2498	2583	RBM47	RNA binding motif protein 47 [Source:HGNC Symbol;Acc:HGNC:30358]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0016554//cytidine to uridine editing	--
ENSG00000163697	11.077	11.249	9.669	12.559	12.812	13.92	1023.49	1010.66	545.75	553.46	716.59	606.07	APBB2	amyloid beta precursor protein binding family B member 2 [Source:HGNC Symbol;Acc:HGNC:582]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0045202//synapse	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006939//smooth muscle contraction;GO:0035556//intracellular signal transduction;GO:0036438//maintenance of lens transparency;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050808//synapse organization;GO:1901988//negative regulation of cell cycle phase transition"	--
ENSG00000163701	3.615	3.37	4.007	4.14	4.438	3.397	176	176	136	169	184	110	IL17RE	interleukin 17 receptor E [Source:HGNC Symbol;Acc:HGNC:18439]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04657//IL-17 signaling pathway	K05168;K05168	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030368//interleukin-17 receptor activity	GO:0006954//inflammatory response;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000163702	13.727	14.394	17.321	17.853	16.565	16.838	589.22	655	564	604.13	636.74	527	IL17RC	interleukin 17 receptor C [Source:HGNC Symbol;Acc:HGNC:18358]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Endocrine and metabolic disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04936//Alcoholic liver disease;ko04657//IL-17 signaling pathway	K05166;K05166;K05166	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030368//interleukin-17 receptor activity	GO:0006954//inflammatory response;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000163703	18.218	18.422	18.093	20.399	20.768	20.976	850.51	880.92	627.15	723.73	815.95	712.93	CRELD1	cysteine rich with EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:14630]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0003756//protein disulfide isomerase activity;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0003197//endocardial cushion development;GO:0003279//cardiac septum development	--
ENSG00000163704	7.38	8.408	7.867	7.698	7.885	6.851	397	469	345	302	360	284	PRRT3	proline rich transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:26591]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000163705	0	0	0	0	0	0	0	0	0	0	0	0	FANCD2OS	FANCD2 opposite strand [Source:HGNC Symbol;Acc:HGNC:28623]	-	-	-	-	-	-	-	--
ENSG00000163710	16.494	17.574	17.407	16.122	18.755	13.988	652	697	507	471	625	401	PCOLCE2	procollagen C-endopeptidase enhancer 2 [Source:HGNC Symbol;Acc:HGNC:8739]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0016504//peptidase activator activity	GO:0010952//positive regulation of peptidase activity;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000163714	14.751	12.768	9.603	7.05	8.979	11.581	1036	881	617	425	647	569	U2SURP	U2 snRNP associated SURP domain containing [Source:HGNC Symbol;Acc:HGNC:30855]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12842	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006396//RNA processing	--
ENSG00000163719	16.888	19.989	23.279	24.16	21.522	21.723	804	985	810	849	862	755	MTMR14	myotubularin related protein 14 [Source:HGNC Symbol;Acc:HGNC:26190]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04140//Autophagy - animal;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K18086;K18086;K18086;K18086	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016236//macroautophagy;GO:0016311//dephosphorylation	--
ENSG00000163728	8.312	4.377	6.033	9.158	7.766	6.136	483	344	297	270	375	356	TTC14	tetratricopeptide repeat domain 14 [Source:HGNC Symbol;Acc:HGNC:24697]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding	-	--
ENSG00000163734	0.045	0	0.061	0	0	0.308	1	0	1	0	0	5	CXCL3	C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: parasitic;Immune disease;Endocrine and metabolic disease;Signal transduction;Signaling molecules and interaction;Immune system;Infectious disease: bacterial;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko05323//Rheumatoid arthritis;ko04936//Alcoholic liver disease;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05134//Legionellosis	K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0045236//CXCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030593//neutrophil chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000163735	0.059	0.118	0	0	0.07	0	3	6	0	0	3	0	CXCL5	C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642]	Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Immune disease;Signal transduction;Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko05323//Rheumatoid arthritis;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05133//Pertussis	K05506;K05506;K05506;K05506;K05506;K05506;K05506	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0042802//identical protein binding;GO:0045236//CXCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0009605//response to external stimulus;GO:0030593//neutrophil chemotaxis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000163736	0	0	0	0	0	0	0	0	0	0	0	0	PPBP	pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K10029;K10029;K10029	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:1904724//tertiary granule lumen	GO:0005125//cytokine activity;GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008083//growth factor activity;GO:0045236//CXCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030593//neutrophil chemotaxis;GO:0042742//defense response to bacterium;GO:0051781//positive regulation of cell division;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:1904659//glucose transmembrane transport	--
ENSG00000163737	0	0	0	0	0	0	0	0	0	0	0	0	PF4	platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05407;K05407;K05407	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0045236//CXCR chemokine receptor binding;GO:0048248//CXCR3 chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016525//negative regulation of angiogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042127//regulation of cell population proliferation;GO:0042832//defense response to protozoan;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0045651//positive regulation of macrophage differentiation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051873//killing by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000163738	0.55	0.777	0.555	0.518	0.579	0.428	24	33	17	18	24	13	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K13403;K13403	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane	GO:0003824//catalytic activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016787//hydrolase activity	GO:0000105//histidine biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0008152//metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0009256//10-formyltetrahydrofolate metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0046655//folic acid metabolic process	--
ENSG00000163739	0.041	0.123	0.111	0.166	0.194	0.79	1	3	2	3	4	14	CXCL1	C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases	Signaling molecules and interaction;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: parasitic;Immune disease;Endocrine and metabolic disease;Signal transduction;Signaling molecules and interaction;Immune system;Infectious disease: bacterial;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko05323//Rheumatoid arthritis;ko04936//Alcoholic liver disease;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05134//Legionellosis	K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505;K05505	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:1904724//tertiary granule lumen	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008047//enzyme activator activity;GO:0008083//growth factor activity;GO:0045236//CXCR chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0030036//actin cytoskeleton organization;GO:0030593//neutrophil chemotaxis;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000163743	14.544	11.393	11.545	11.067	12.58	14.902	501	398	282	284	381	367	RCHY1	ring finger and CHY zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17479]	Genetic Information Processing;Human Diseases;Cellular Processes	"Folding, sorting and degradation;Infectious disease: viral;Cell growth and death"	ko04120//Ubiquitin mediated proteolysis;ko05162//Measles;ko04115//p53 signaling pathway	K10144;K10144;K10144	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0002039//p53 binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0070987//error-free translesion synthesis	--
ENSG00000163746	0	0	0.207	0	0	0.108	0	0	4	0	0	2	PLSCR2	phospholipid scramblase 2 [Source:HGNC Symbol;Acc:HGNC:16494]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity;GO:0046872//metal ion binding	GO:0017121//plasma membrane phospholipid scrambling	--
ENSG00000163749	0	0	0	0	0	0	0	0	0	0	0	0	CCDC158	coiled-coil domain containing 158 [Source:HGNC Symbol;Acc:HGNC:26374]	-	-	-	-	-	-	-	--
ENSG00000163751	0	0	0	0	0.065	0	0	0	0	0	2	0	CPA3	carboxypeptidase A3 [Source:HGNC Symbol;Acc:HGNC:2298]	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Endocrine system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04614//Renin-angiotensin system	K08780;K08780;K08780	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0062023//collagen-containing extracellular matrix	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0002002//regulation of angiotensin levels in blood;GO:0002003//angiotensin maturation;GO:0006508//proteolysis	--
ENSG00000163754	24.187	24.753	23.518	22.296	20.057	19.743	973.61	971.73	677.14	649.52	676.11	567.27	GYG1	glycogenin 1 [Source:HGNC Symbol;Acc:HGNC:4699]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K00750;K00750	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0043202//lysosomal lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0008466//glycogenin glucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0102751//UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity	GO:0005978//glycogen biosynthetic process	--
ENSG00000163755	17.363	15.49	16.679	14.981	15.708	18.148	1592.71	1435.36	1106.32	1028.92	1202.02	1207.52	HPS3	HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 [Source:HGNC Symbol;Acc:HGNC:15597]	-	-	-	-	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0031084//BLOC-2 complex	GO:0005515//protein binding	GO:0006996//organelle organization;GO:0043473//pigmentation;GO:0046907//intracellular transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000163762	4.117	6.293	7.353	6.632	5.549	5.422	195	172	172	147	157	145	TM4SF18	transmembrane 4 L six family member 18 [Source:HGNC Symbol;Acc:HGNC:25181]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000163781	5.264	4.283	4.064	2.831	3.169	3.146	638	526	360	256	325	277	TOPBP1	DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10728	GO:0000794//condensed nuclear chromosome;GO:0000922//spindle pole;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016604//nuclear body;GO:0016605//PML body;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0070532//BRCA1-B complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding	GO:0006259//DNA metabolic process;GO:0006270//DNA replication initiation;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010212//response to ionizing radiation;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0035825//homologous recombination	--
ENSG00000163785	27.119	28.14	28.12	23.404	24.188	24.029	1560	1564	1081	1006	1197	1014	RYK	receptor like tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10481]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signal transduction	ko04360//Axon guidance;ko04310//Wnt signaling pathway	K05128;K05128	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017147//Wnt-protein binding;GO:0042813//Wnt-activated receptor activity;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0022008//neurogenesis;GO:0022038//corpus callosum development;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0033278//cell proliferation in midbrain;GO:0033674//positive regulation of kinase activity;GO:0035567//non-canonical Wnt signaling pathway;GO:0036518//chemorepulsion of dopaminergic neuron axon;GO:0043410//positive regulation of MAPK cascade;GO:0048705//skeletal system morphogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0060070//canonical Wnt signaling pathway;GO:0071679//commissural neuron axon guidance;GO:1904938//planar cell polarity pathway involved in axon guidance;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904953//Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	--
ENSG00000163788	6.094	5.136	5.855	4.521	4.669	6.462	620	539	444	360	412	484	SNRK	SNF related kinase [Source:HGNC Symbol;Acc:HGNC:30598]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030099//myeloid cell differentiation;GO:0035556//intracellular signal transduction	--
ENSG00000163792	0	0	0	0	0	0	0	0	0	0	0	0	TCF23	transcription factor 23 [Source:HGNC Symbol;Acc:HGNC:18602]	-	-	-	-	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0032502//developmental process;GO:0046697//decidualization;GO:0051148//negative regulation of muscle cell differentiation	bHLH
ENSG00000163793	0	0	0	0	0	0	0	0	0	0	0	0	DNAJC5G	DnaJ heat shock protein family (Hsp40) member C5 gamma [Source:HGNC Symbol;Acc:HGNC:24844]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09525	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000163794	0.364	0.362	0.082	0.082	0.646	0.583	6	6	1	1	9	7	UCN	urocortin [Source:HGNC Symbol;Acc:HGNC:12516]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23142	GO:0005576//extracellular region;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043196//varicosity;GO:0043204//perikaryon;GO:0043679//axon terminus	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0046811//histone deacetylase inhibitor activity;GO:0051430//corticotropin-releasing hormone receptor 1 binding;GO:0051431//corticotropin-releasing hormone receptor 2 binding	"GO:0001934//positive regulation of protein phosphorylation;GO:0001964//startle response;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007565//female pregnancy;GO:0007605//sensory perception of sound;GO:0007611//learning or memory;GO:0007631//feeding behavior;GO:0008306//associative learning;GO:0009060//aerobic respiration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010996//response to auditory stimulus;GO:0030157//pancreatic juice secretion;GO:0030307//positive regulation of cell growth;GO:0031064//negative regulation of histone deacetylation;GO:0031175//neuron projection development;GO:0032099//negative regulation of appetite;GO:0032355//response to estradiol;GO:0032755//positive regulation of interleukin-6 production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034199//activation of protein kinase A activity;GO:0035176//social behavior;GO:0035483//gastric emptying;GO:0042311//vasodilation;GO:0042756//drinking behavior;GO:0043066//negative regulation of apoptotic process;GO:0043117//positive regulation of vascular permeability;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045727//positive regulation of translation;GO:0045740//positive regulation of DNA replication;GO:0045776//negative regulation of blood pressure;GO:0045792//negative regulation of cell size;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046888//negative regulation of hormone secretion;GO:0048265//response to pain;GO:0051384//response to glucocorticoid;GO:0051461//positive regulation of corticotropin secretion;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060452//positive regulation of cardiac muscle contraction;GO:0060455//negative regulation of gastric acid secretion;GO:0060547//negative regulation of necrotic cell death;GO:0060548//negative regulation of cell death;GO:0090280//positive regulation of calcium ion import;GO:1901215//negative regulation of neuron death;GO:2000252//negative regulation of feeding behavior;GO:2000987//positive regulation of behavioral fear response"	--
ENSG00000163795	5.357	5.696	6.362	5.399	5.058	6.257	238.22	254.11	208.25	177.09	189.18	202.11	ZNF513	zinc finger protein 513 [Source:HGNC Symbol;Acc:HGNC:26498]	-	-	-	-	GO:0005634//nucleus	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007601//visual perception;GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye	zf-C2H2
ENSG00000163798	6.564	5.8	6.328	4.527	4.755	5.256	360.31	318	255.04	183.86	219.64	214	SLC4A1AP	solute carrier family 4 member 1 adaptor protein [Source:HGNC Symbol;Acc:HGNC:13813]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003729//mRNA binding;GO:0005515//protein binding	-	--
ENSG00000163803	0.104	0.036	0.018	0.055	0.093	0.037	9	4	1	3	6	2	PLB1	phospholipase B1 [Source:HGNC Symbol;Acc:HGNC:30041]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism;ko04977//Vitamin digestion and absorption	K14621;K14621;K14621;K14621;K14621;K14621;K14621	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	"GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0004806//triglyceride lipase activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0047499//calcium-independent phospholipase A2 activity;GO:0050253//retinyl-palmitate esterase activity;GO:0102545//phosphatidyl phospholipase B activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0019433//triglyceride catabolic process;GO:0034478//phosphatidylglycerol catabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042572//retinol metabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0046340//diacylglycerol catabolic process;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000163806	0.09	0	0.109	0	0.067	0.104	2.12	0	1.26	0	2.07	1.19	SPDYA	speedy/RINGO cell cycle regulator family member A [Source:HGNC Symbol;Acc:HGNC:30613]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007140//male meiotic nuclear division;GO:0008284//positive regulation of cell population proliferation;GO:0032147//activation of protein kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045860//positive regulation of protein kinase activity	--
ENSG00000163807	12.644	10.681	8.894	8.317	9.337	9.237	1332	1131	692	649	831	708	KIAA1143	KIAA1143 [Source:HGNC Symbol;Acc:HGNC:29198]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000163808	0.188	0.146	0.085	0.091	0.156	0.099	14	9	3	4	13	7	KIF15	kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005873//plus-end kinesin complex;GO:0005874//microtubule;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:1901673//regulation of mitotic spindle assembly	--
ENSG00000163810	0	0	0	0	0	0	0	0	0	0	0	0	TGM4	transglutaminase 4 [Source:HGNC Symbol;Acc:HGNC:11780]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	GO:0018149//peptide cross-linking	--
ENSG00000163811	6.477	7.351	8.351	6.309	4.948	4.895	471	390	322	247	304	259	WDR43	WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14546	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0000993//RNA polymerase II complex binding;GO:0003711//transcription elongation regulator activity;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0042254//ribosome biogenesis;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:2000036//regulation of stem cell population maintenance;GO:2000234//positive regulation of rRNA processing	--
ENSG00000163812	23.911	30.691	27.883	27.974	25.548	30.405	1491	1597	1202	1283	1361	1183	ZDHHC3	zinc finger DHHC-type palmitoyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:18470]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0042803//protein homodimerization activity;GO:0140439//protein-cysteine S-stearoyltransferase activity	"GO:0006612//protein targeting to membrane;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0044873//lipoprotein localization to membrane;GO:0072659//protein localization to plasma membrane;GO:1902685//positive regulation of receptor localization to synapse;GO:1903546//protein localization to photoreceptor outer segment"	--
ENSG00000163814	2.383	2.371	1.226	0.186	0.688	0.444	283	271	112	17	61	40	CDCP1	CUB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:24357]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000163815	0	0	0	0	0.076	0	0	0	0	0	1	0	CLEC3B	C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891]	-	-	-	-	GO:0001652//granular component;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031089//platelet dense granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0030246//carbohydrate binding;GO:0036143//kringle domain binding	GO:0001503//ossification;GO:0010756//positive regulation of plasminogen activation;GO:0030282//bone mineralization;GO:0071310//cellular response to organic substance;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000163817	51.648	54.345	73.604	91.02	86.373	83.391	5463	5873	5565	7213	7483	6376	SLC6A20	solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005298//proline:sodium symporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015188//L-isoleucine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015199//amino-acid betaine transmembrane transporter activity;GO:0015293//symporter activity	GO:0006865//amino acid transport;GO:0015816//glycine transport;GO:0015824//proline transport;GO:0015838//amino-acid betaine transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0089718//amino acid import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1903806//L-isoleucine import across plasma membrane;GO:1904271//L-proline import across plasma membrane;GO:1905647//proline import across plasma membrane	--
ENSG00000163818	13.308	11.4	10.186	9.257	9.051	8.514	736	610	437	344	440	312	LZTFL1	leucine zipper transcription factor like 1 [Source:HGNC Symbol;Acc:HGNC:6741]	-	-	-	-	GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0007283//spermatogenesis;GO:0030317//flagellated sperm motility;GO:1903565//negative regulation of protein localization to cilium;GO:1903568//negative regulation of protein localization to ciliary membrane	--
ENSG00000163820	14.16	13.045	13.566	10.87	13.616	13.607	2211	2151	1624	1251	1764	1560	FYCO1	FYVE and coiled-coil domain autophagy adaptor 1 [Source:HGNC Symbol;Acc:HGNC:14673]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K21954	GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0072383//plus-end-directed vesicle transport along microtubule;GO:1901098//positive regulation of autophagosome maturation	--
ENSG00000163823	0	0	0	0	0.065	0	0	0	0	0	3	0	CCR1	C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04176;K04176;K04176;K04176;K04176	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0035717//chemokine (C-C motif) ligand 7 binding;GO:0071791//chemokine (C-C motif) ligand 5 binding	"GO:0002407//dendritic cell chemotaxis;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0009611//response to wounding;GO:0010629//negative regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0019722//calcium-mediated signaling;GO:0030335//positive regulation of cell migration;GO:0030502//negative regulation of bone mineralization;GO:0045672//positive regulation of osteoclast differentiation;GO:0051928//positive regulation of calcium ion transport;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090026//positive regulation of monocyte chemotaxis"	--
ENSG00000163825	0	0	0	0	0	0	0	0	0	0	0	0	RTP3	receptor transporter protein 3 [Source:HGNC Symbol;Acc:HGNC:15572]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031849//olfactory receptor binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006612//protein targeting to membrane;GO:0051205//protein insertion into membrane	--
ENSG00000163827	1.666	1.465	1.056	1.325	0.91	0.713	169	137	75	59	78	45	LRRC2	leucine rich repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14676]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000163832	11.543	12.174	12.334	11.475	10.742	11.16	292	320	225	196	234	211	ELP6	elongator acetyltransferase complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:25976]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033588//elongator holoenzyme complex	GO:0003674//molecular_function	GO:0002098//tRNA wobble uridine modification;GO:0006417//regulation of translation;GO:0008033//tRNA processing;GO:0008150//biological_process;GO:0030335//positive regulation of cell migration	--
ENSG00000163833	0	0	0	0	0	0	0	0	0	0	0	0	FBXO40	F-box protein 40 [Source:HGNC Symbol;Acc:HGNC:29816]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0042692//muscle cell differentiation	--
ENSG00000163840	5.876	5.48	5.025	3.949	4.422	5.537	703	659	444	350	447	482	DTX3L	deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06058	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex	GO:0004842//ubiquitin-protein transferase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0097677//STAT family protein binding	"GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007219//Notch signaling pathway;GO:0008333//endosome to lysosome transport;GO:0010390//histone monoubiquitination;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0032092//positive regulation of protein binding;GO:0033522//histone H2A ubiquitination;GO:0033523//histone H2B ubiquitination;GO:0035563//positive regulation of chromatin binding;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051607//defense response to virus;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:1900182//positive regulation of protein localization to nucleus;GO:1901666//positive regulation of NAD+ ADP-ribosyltransferase activity;GO:1902966//positive regulation of protein localization to early endosome;GO:2000646//positive regulation of receptor catabolic process;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000163848	9.126	6.702	6.495	4.487	6.094	6.271	1189	762	559	437	582	577	ZNF148	zinc finger protein 148 [Source:HGNC Symbol;Acc:HGNC:12933]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006968//cellular defense response;GO:0007276//gamete generation;GO:0010629//negative regulation of gene expression;GO:0021762//substantia nigra development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0065003//protein-containing complex assembly"	zf-C2H2
ENSG00000163864	9.504	8.325	9.641	12.105	12.628	12.327	357.29	294.4	254.15	308.74	348.38	316.93	NMNAT3	nicotinamide nucleotide adenylyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:20989]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K06210;K06210	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030424//axon;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0003824//catalytic activity;GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016432//tRNA-uridine aminocarboxypropyltransferase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0008033//tRNA processing;GO:0009058//biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0009435//NAD biosynthetic process;GO:0009611//response to wounding;GO:0019363//pyridine nucleotide biosynthetic process;GO:0034612//response to tumor necrosis factor	--
ENSG00000163866	12.644	15.103	14.732	16.514	14.274	17.388	351	419	288	368	345	366	SMIM12	small integral membrane protein 12 [Source:HGNC Symbol;Acc:HGNC:25154]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000163867	3.055	2.77	2.823	2.208	2.42	2.818	269.13	212.92	164.43	110.29	166.39	160.5	ZMYM6	zinc finger MYM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:13050]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis	--
ENSG00000163870	16.394	18.499	17.121	20.775	21.169	18.733	641	695	489	590	692	527	TPRA1	transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007568//aging;GO:0040016//embryonic cleavage;GO:1901991//negative regulation of mitotic cell cycle phase transition	--
ENSG00000163872	21.282	20.568	18.714	14.771	16.929	17.382	2760	2659	1835	1481	1936	1712	YEATS2	YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489]	-	-	-	-	GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0005515//protein binding;GO:0017025//TBP-class protein binding;GO:0042393//histone binding;GO:0140030//modification-dependent protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0031063//regulation of histone deacetylation;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000163873	0.025	0.045	0.034	0	0	0	5	9	5	0	0	0	GRIK3	glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04724//Glutamatergic synapse	K05203;K05203	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0032839//dendrite cytoplasm;GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity;GO:0038023//signaling receptor activity;GO:0099507//ligand-gated ion channel activity involved in regulation of presynaptic membrane potential;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0042391//regulation of membrane potential;GO:0050804//modulation of chemical synaptic transmission;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0099505//regulation of presynaptic membrane potential"	--
ENSG00000163874	1.468	1.914	1.968	1.251	1.976	1.748	81	106	80	51	92	70	ZC3H12A	zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0032991//protein-containing complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042406//extrinsic component of endoplasmic reticulum membrane	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004532//exoribonuclease activity;GO:0004540//ribonuclease activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035198//miRNA binding;GO:0035613//RNA stem-loop binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0043022//ribosome binding;GO:0046872//metal ion binding	"GO:0000294//nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay;GO:0001525//angiogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002757//immune response-activating signal transduction;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0010587//miRNA catabolic process;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0010884//positive regulation of lipid storage;GO:0010942//positive regulation of cell death;GO:0016579//protein deubiquitination;GO:0030154//cell differentiation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032689//negative regulation of interferon-gamma production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034599//cellular response to oxidative stress;GO:0042149//cellular response to glucose starvation;GO:0042307//positive regulation of protein import into nucleus;GO:0043031//negative regulation of macrophage activation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044828//negative regulation by host of viral genome replication;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045600//positive regulation of fat cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050852//T cell receptor signaling pathway;GO:0051259//protein complex oligomerization;GO:0051607//defense response to virus;GO:0055118//negative regulation of cardiac muscle contraction;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0098586//cellular response to virus;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900119//positive regulation of execution phase of apoptosis;GO:1900745//positive regulation of p38MAPK cascade;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1903003//positive regulation of protein deubiquitination;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1903936//cellular response to sodium arsenite;GO:1904637//cellular response to ionomycin;GO:1990869//cellular response to chemokine;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000627//positive regulation of miRNA catabolic process"	--
ENSG00000163875	27.178	28.493	27.815	24.972	26.156	22.563	787	729.02	549	495	539	471	MEAF6	MYST/Esa1 associated factor 6 [Source:HGNC Symbol;Acc:HGNC:25674]	-	-	-	-	"GO:0000123//histone acetyltransferase complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0070776//MOZ/MORF histone acetyltransferase complex"	GO:0005515//protein binding	"GO:0001558//regulation of cell growth;GO:0006275//regulation of DNA replication;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016570//histone modification;GO:0016573//histone acetylation;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050793//regulation of developmental process;GO:0051726//regulation of cell cycle;GO:1903706//regulation of hemopoiesis;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000278//regulation of DNA biosynthetic process;GO:2000779//regulation of double-strand break repair"	--
ENSG00000163877	4.891	4.982	4.888	5.56	4.273	4.831	462	473	341	389	341	332	SNIP1	Smad nuclear interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30587]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0071005//U2-type precatalytic spliceosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008380//RNA splicing;GO:0031047//gene silencing by RNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA"	--
ENSG00000163879	11.319	13.892	10.532	8.718	8.792	9.66	617	762	424	352	408	384	DNALI1	dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10410;K10410;K10410	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0030175//filopodium;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097546//ciliary base;GO:0097729//9+2 motile cilium;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0045504//dynein heavy chain binding	-	--
ENSG00000163882	18.96	17.898	20.103	17.291	17.579	21.509	390	354	314	266	303	312	POLR2H	"RNA polymerase II, I and III subunit H [Source:HGNC Symbol;Acc:HGNC:9195]"	Human Diseases;Organismal Systems;Genetic Information Processing	Neurodegenerative disease;Immune system;Transcription	ko05016//Huntington disease;ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03016;K03016;K03016	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005666//RNA polymerase III complex;GO:0005730//nucleolus;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol;GO:0032993//protein-DNA complex"	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000163884	3.151	2.833	2.21	2.562	4.269	6.183	166	150	86	100	190	237	KLF15	Kruppel like factor 15 [Source:HGNC Symbol;Acc:HGNC:14536]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001678//cellular glucose homeostasis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010001//glial cell differentiation;GO:0010468//regulation of gene expression;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030111//regulation of Wnt signaling pathway;GO:0032868//response to insulin;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046326//positive regulation of glucose import;GO:0072112//glomerular visceral epithelial cell differentiation;GO:1901653//cellular response to peptide;GO:2000757//negative regulation of peptidyl-lysine acetylation"	zf-C2H2
ENSG00000163885	0.402	0.024	0.033	0	0	0	5	1	1	0	0	0	CFAP100	cilia and flagella associated protein 100 [Source:HGNC Symbol;Acc:HGNC:26842]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097545//axonemal outer doublet	GO:0005515//protein binding;GO:0070840//dynein complex binding	GO:0003341//cilium movement;GO:0036159//inner dynein arm assembly	--
ENSG00000163888	0.531	0.066	0.09	0.09	0.157	0.046	16	2	2	2	4	1	CAMK2N2	calcium/calmodulin dependent protein kinase II inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:24197]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0045202//synapse	GO:0004860//protein kinase inhibitor activity;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding	GO:0006469//negative regulation of protein kinase activity	--
ENSG00000163898	0.134	0.026	0.125	0.032	0.029	0.034	2	2	1	1	2	2	LIPH	lipase H [Source:HGNC Symbol;Acc:HGNC:18483]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity;GO:0008201//heparin binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process	--
ENSG00000163900	4.795	5.215	5.329	5.917	4.455	5.646	266	305	229	240	219	239	TMEM41A	transmembrane protein 41A [Source:HGNC Symbol;Acc:HGNC:30544]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000163902	199.026	191.444	196.458	213.161	204.575	217.343	9077	9062	6643	7364	7982	7377	RPN1	ribophorin I [Source:HGNC Symbol;Acc:HGNC:10381]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K12666;K12666;K12666;K12666	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome	GO:0003723//RNA binding;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine	--
ENSG00000163904	20.07	15.968	19.567	17.41	17.043	17.805	1268	1032	859	736	887	849	SENP2	SUMO specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:23116]	Environmental Information Processing;Genetic Information Processing	Signal transduction;Translation	ko04310//Wnt signaling pathway;ko03013//Nucleocytoplasmic transport	K03345;K03345	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016605//PML body;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070139//SUMO-specific endopeptidase activity;GO:0070140//SUMO-specific isopeptidase activity	GO:0006508//proteolysis;GO:0007507//heart development;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0016926//protein desumoylation;GO:0030111//regulation of Wnt signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0031648//protein destabilization;GO:0032875//regulation of DNA endoreduplication;GO:0035562//negative regulation of chromatin binding;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:0060707//trophoblast giant cell differentiation;GO:0060711//labyrinthine layer development;GO:0060712//spongiotrophoblast layer development;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000163909	0.083	0.094	0.096	0.064	0.07	0.081	7	8	6	4	5	5	HEYL	hes related family bHLH transcription factor with YRPW motif like [Source:HGNC Symbol;Acc:HGNC:4882]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05224//Breast cancer;ko04330//Notch signaling pathway	K09091;K09091;K09091;K09091	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0050683//AF-1 domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003151//outflow tract morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003203//endocardial cushion morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0010629//negative regulation of gene expression;GO:0014031//mesenchymal cell development;GO:0032835//glomerulus development;GO:0035914//skeletal muscle cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045666//positive regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060412//ventricular septum morphogenesis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0061314//Notch signaling involved in heart development;GO:0071773//cellular response to BMP stimulus;GO:0072014//proximal tubule development"	bHLH
ENSG00000163913	18.344	18.759	18.933	18.246	19.847	16.613	1469	1483	1107	1065	1309	960	IFT122	intraflagellar transport 122 [Source:HGNC Symbol;Acc:HGNC:13556]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0030991//intraciliary transport particle A;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097730//non-motile cilium	GO:0005515//protein binding	GO:0001843//neural tube closure;GO:0010172//embryonic body morphogenesis;GO:0030030//cell projection organization;GO:0035050//embryonic heart tube development;GO:0035721//intraciliary retrograde transport;GO:0042073//intraciliary transport;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048593//camera-type eye morphogenesis;GO:0060173//limb development;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000163914	0	0	0	0	0.021	0.024	0	0	0	0	1	1	RHO	rhodopsin [Source:HGNC Symbol;Acc:HGNC:10012]	Organismal Systems	Sensory system	ko04744//Phototransduction	K04250	GO:0000139//Golgi membrane;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0060342//photoreceptor inner segment membrane;GO:0097225//sperm midpiece;GO:0097381//photoreceptor disc membrane;GO:1990913//sperm head plasma membrane	GO:0004930//G protein-coupled receptor activity;GO:0005502//11-cis retinal binding;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity;GO:0046872//metal ion binding	"GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0007603//phototransduction, visible light;GO:0009416//response to light stimulus;GO:0009583//detection of light stimulus;GO:0016038//absorption of visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0018298//protein-chromophore linkage;GO:0043052//thermotaxis;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0050953//sensory perception of light stimulus;GO:0050960//detection of temperature stimulus involved in thermoception;GO:0060041//retina development in camera-type eye;GO:0071482//cellular response to light stimulus"	--
ENSG00000163918	5.756	5.45	4.322	1.764	3.479	5.875	129	117	71	37	70	100	RFC4	replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03430//Mismatch repair	K10755;K10755;K10755	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex;GO:0031390//Ctf18 RFC-like complex;GO:0031391//Elg1 RFC-like complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006281//DNA repair;GO:0032508//DNA duplex unwinding;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000163923	4.972	4.949	5.194	5.625	3.679	3.996	75	75	58	63	47	44	RPL39L	ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02924;K02924	GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0007283//spermatogenesis	--
ENSG00000163930	28.858	32.329	30.45	35.639	31.17	31.816	2048	2245	1588	1859	1855	1634	BAP1	BRCA1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:950]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035517//PR-DUB complex	GO:0003682//chromatin binding;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0001558//regulation of cell growth;GO:0006325//chromatin organization;GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0010035//response to inorganic substance;GO:0016579//protein deubiquitination;GO:0035520//monoubiquitinated protein deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050727//regulation of inflammatory response;GO:0051726//regulation of cell cycle;GO:0061519//macrophage homeostasis;GO:0071108//protein K48-linked deubiquitination;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1903955//positive regulation of protein targeting to mitochondrion"	--
ENSG00000163931	208.622	202.086	209.981	259.681	237.355	245.919	9076	8727	6687	8211	8786	7731	TKT	transketolase [Source:HGNC Symbol;Acc:HGNC:11834]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00615;K00615;K00615;K00615	GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004802//transketolase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030976//thiamine pyrophosphate binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0040008//regulation of growth;GO:0046166//glyceraldehyde-3-phosphate biosynthetic process;GO:0046390//ribose phosphate biosynthetic process"	--
ENSG00000163932	15.134	16.658	13.094	9.519	11.89	9.157	776	823	513	376	518	348	PRKCD	protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial;Cancer: overview;Cardiovascular disease;Immune system;Immune system;Immune system;Transport and catabolism;Endocrine system;Circulatory system;Nervous system;Endocrine and metabolic disease;Immune system;Endocrine and metabolic disease;Sensory system;Endocrine system;Endocrine and metabolic disease	ko05020//Prion disease;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04140//Autophagy - animal;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04722//Neurotrophin signaling pathway;ko04931//Insulin resistance;ko04625//C-type lectin receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04750//Inflammatory mediator regulation of TRP channels;ko04912//GnRH signaling pathway;ko04930//Type II diabetes mellitus	K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068;K06068	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0035578//azurophil granule lumen;GO:0036019//endolysosome;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004699//calcium-independent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008047//enzyme activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0043560//insulin receptor substrate binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010469//regulation of signaling receptor activity;GO:0016064//immunoglobulin mediated immune response;GO:0016310//phosphorylation;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0023021//termination of signal transduction;GO:0030837//negative regulation of actin filament polymerization;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0032091//negative regulation of protein binding;GO:0032147//activation of protein kinase activity;GO:0032930//positive regulation of superoxide anion generation;GO:0032956//regulation of actin cytoskeleton organization;GO:0034351//negative regulation of glial cell apoptotic process;GO:0034644//cellular response to UV;GO:0035307//positive regulation of protein dephosphorylation;GO:0035556//intracellular signal transduction;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042100//B cell proliferation;GO:0042119//neutrophil activation;GO:0042307//positive regulation of protein import into nucleus;GO:0042742//defense response to bacterium;GO:0043407//negative regulation of MAP kinase activity;GO:0043488//regulation of mRNA stability;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050821//protein stabilization;GO:0051490//negative regulation of filopodium assembly;GO:0060326//cell chemotaxis;GO:0070301//cellular response to hydrogen peroxide;GO:0071447//cellular response to hydroperoxide;GO:0080090//regulation of primary metabolic process;GO:0090331//negative regulation of platelet aggregation;GO:0090398//cellular senescence;GO:1900163//positive regulation of phospholipid scramblase activity;GO:1904385//cellular response to angiotensin;GO:2000303//regulation of ceramide biosynthetic process;GO:2000304//positive regulation of ceramide biosynthetic process;GO:2000753//positive regulation of glucosylceramide catabolic process;GO:2000755//positive regulation of sphingomyelin catabolic process;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000163933	9.501	11.776	10.487	11.74	10.751	9.767	489.74	511	381	406	444	376	RFT1	RFT1 homolog [Source:HGNC Symbol;Acc:HGNC:30220]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0034202//glycolipid floppase activity	GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0008643//carbohydrate transport;GO:0034203//glycolipid translocation	--
ENSG00000163935	2.467	3.473	2.72	2.181	2.582	2.505	233	256	158	144	182	157	SFMBT1	Scm like with four mbt domains 1 [Source:HGNC Symbol;Acc:HGNC:20255]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048635//negative regulation of muscle organ development"	--
ENSG00000163938	16.04	15.699	13.573	10.973	9.091	13.149	630	618	383	303	309	372	GNL3	G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14538	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030496//midbody	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0048027//mRNA 5'-UTR binding	"GO:0008283//cell population proliferation;GO:0017145//stem cell division;GO:0019827//stem cell population maintenance;GO:0032206//positive regulation of telomere maintenance;GO:0033235//positive regulation of protein sumoylation;GO:0042127//regulation of cell population proliferation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904816//positive regulation of protein localization to chromosome, telomeric region"	--
ENSG00000163939	24.495	19.705	19.176	15.131	15.288	16.793	2623	1982	1529	1165	1389	1352	PBRM1	polybromo 1 [Source:HGNC Symbol;Acc:HGNC:30064]	Human Diseases	Cancer: specific types	ko05225//Hepatocellular carcinoma	K11757	GO:0000228//nuclear chromosome;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair	HMG
ENSG00000163945	1.279	1.144	1.807	1.382	2.13	1.151	261	238	199	205	282	188	UVSSA	UV stimulated scaffold protein A [Source:HGNC Symbol;Acc:HGNC:29304]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0016567//protein ubiquitination	--
ENSG00000163946	9.898	6.765	6.077	5.03	6.393	6.359	1339.35	912.93	633	510.79	735.6	646.58	TASOR	transcription activation suppressor [Source:HGNC Symbol;Acc:HGNC:30314]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0001701//in utero embryonic development;GO:0008595//anterior/posterior axis specification, embryo;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0060809//mesodermal to mesenchymal transition involved in gastrulation;GO:0090307//mitotic spindle assembly;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly;GO:0097355//protein localization to heterochromatin"	--
ENSG00000163947	53.719	49.367	43.436	39.492	43.821	49.465	3344	3227	2129	1959	2327	2296	ARHGEF3	Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007266//Rho protein signal transduction;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000163950	32.606	30.442	31.359	27.939	25.841	33.497	1204	1127	842	760	794	906	SLBP	stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0062073//histone mRNA stem-loop binding complex;GO:0071204//histone pre-mRNA 3'end processing complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0071207//histone pre-mRNA stem-loop binding;GO:0071208//histone pre-mRNA DCP binding	GO:0002191//cap-dependent translational initiation;GO:0006397//mRNA processing;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:0051028//mRNA transport	--
ENSG00000163956	73.43	68.702	64.853	71.617	67.805	68.534	3263	3319	2477	2392	2750	2439	LRPAP1	LDL receptor related protein associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6701]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22290	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005801//cis-Golgi network;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0031904//endosome lumen;GO:0031982//vesicle;GO:0048237//rough endoplasmic reticulum lumen	GO:0001540//amyloid-beta binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0035473//lipase binding;GO:0048018//receptor ligand activity;GO:0048019//receptor antagonist activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0070326//very-low-density lipoprotein particle receptor binding	GO:0002091//negative regulation of receptor internalization;GO:0007165//signal transduction;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0032091//negative regulation of protein binding;GO:0048259//regulation of receptor-mediated endocytosis;GO:0060548//negative regulation of cell death;GO:0150093//amyloid-beta clearance by transcytosis;GO:1900116//extracellular negative regulation of signal transduction;GO:1900222//negative regulation of amyloid-beta clearance;GO:1900223//positive regulation of amyloid-beta clearance;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000163958	0	0	0	0.05	0	0	0	0	0	1	0	0	ZDHHC19	zinc finger DHHC-type palmitoyltransferase 19 [Source:HGNC Symbol;Acc:HGNC:20713]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0097356//perinucleolar compartment	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation	--
ENSG00000163959	0.17	0	0.091	0	0	0	3	0	2	0	0	0	SLC51A	solute carrier family 51 subunit alpha [Source:HGNC Symbol;Acc:HGNC:29955]	Organismal Systems	Digestive system	ko04976//Bile secretion	K14360	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0015125//bile acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0015721//bile acid and bile salt transport;GO:0032782//bile acid secretion;GO:0055085//transmembrane transport;GO:0071702//organic substance transport	--
ENSG00000163960	7.771	6.824	7.535	6.685	5.855	7.694	1276	1146	888	687	825	785	UBXN7	UBX domain protein 7 [Source:HGNC Symbol;Acc:HGNC:29119]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000163961	2.919	3.099	2.521	2.057	2.157	2.199	300	292	177	162	181	148	RNF168	ring finger protein 168 [Source:HGNC Symbol;Acc:HGNC:26661]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0035861//site of double-strand break	GO:0003682//chromatin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0016567//protein ubiquitination;GO:0033522//histone H2A ubiquitination;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0035518//histone H2A monoubiquitination;GO:0036297//interstrand cross-link repair;GO:0036351//histone H2A-K13 ubiquitination;GO:0036352//histone H2A-K15 ubiquitination;GO:0045190//isotype switching;GO:0045739//positive regulation of DNA repair;GO:0070534//protein K63-linked ubiquitination;GO:0070535//histone H2A K63-linked ubiquitination	--
ENSG00000163964	12.262	12.078	9.85	10.996	8.982	10.109	609	550	401	412	408	400	PIGX	phosphatidylinositol glycan anchor biosynthesis class X [Source:HGNC Symbol;Acc:HGNC:26046]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K07541;K07541	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000163975	3.873	4.548	3.417	3.514	3.311	3.31	228	252	163	178	205	154	MELTF	melanotransferrin [Source:HGNC Symbol;Acc:HGNC:7037]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0010756//positive regulation of plasminogen activation;GO:0055072//iron ion homeostasis;GO:0090091//positive regulation of extracellular matrix disassembly;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading	--
ENSG00000163982	0	0	0	0	0	0	0	0	0	0	0	0	OTOP1	otopetrin 1 [Source:HGNC Symbol;Acc:HGNC:19656]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015252//proton channel activity	GO:0006811//ion transport;GO:0009590//detection of gravity;GO:0031214//biomineral tissue development;GO:0032869//cellular response to insulin stimulus;GO:0042472//inner ear morphogenesis;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:1902600//proton transmembrane transport	--
ENSG00000163993	0	0	0	0	0.363	0.141	0	0	0	0	3	1	S100P	S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031528//microvillus membrane;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0010033//response to organic substance;GO:0043542//endothelial cell migration	--
ENSG00000163995	0.374	0.399	0.43	0.558	0.305	0.221	23	20	19	20	14	7	ABLIM2	actin binding LIM protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19195]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07520	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	"GO:0006351//transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization"	--
ENSG00000164002	2.647	2.562	2.848	2.186	2.712	2.011	106	104	84	65	88	60	EXO5	exonuclease 5 [Source:HGNC Symbol;Acc:HGNC:26115]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0036297//interstrand cross-link repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000164007	90.588	95.45	95.717	100.429	100.449	102.266	4623	4902	3651	3770	4333	3884	CLDN19	claudin 19 [Source:HGNC Symbol;Acc:HGNC:2040]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0043296//apical junction complex;GO:0048471//perinuclear region of cytoplasm	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0019227//neuronal action potential propagation;GO:0030336//negative regulation of cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0043297//apical junction assembly;GO:0050896//response to stimulus;GO:0061045//negative regulation of wound healing;GO:0070830//bicellular tight junction assembly;GO:0120193//tight junction organization;GO:0150111//regulation of transepithelial transport;GO:1901890//positive regulation of cell junction assembly	--
ENSG00000164008	5.272	5.587	4.127	6.008	5.697	5.135	244.77	249.58	140.82	191	177.61	145.12	C1orf50	chromosome 1 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:28795]	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008150//biological_process	--
ENSG00000164010	5.537	7.041	6.503	6.883	5.984	6.982	336	424	292	306	319	294	ERMAP	erythroblast membrane associated protein (Scianna blood group) [Source:HGNC Symbol;Acc:HGNC:15743]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0050852//T cell receptor signaling pathway	--
ENSG00000164011	5.362	4.584	4.759	5.301	4.42	5.572	172	145	116	127	118	125	ZNF691	zinc finger protein 691 [Source:HGNC Symbol;Acc:HGNC:28028]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000164022	11.343	11.786	13.032	10.967	8.089	10.957	535.1	452.8	358	303	322	357	AIMP1	aminoacyl tRNA synthetase complex interacting multifunctional protein 1 [Source:HGNC Symbol;Acc:HGNC:10648]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0051020//GTPase binding	GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006412//translation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0050900//leukocyte migration;GO:0070094//positive regulation of glucagon secretion	--
ENSG00000164023	15.719	11.965	12.123	8.729	9.601	12.89	1766	1401	941	753	888	924	SGMS2	sphingomyelin synthase 2 [Source:HGNC Symbol;Acc:HGNC:28395]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04714;K04714;K04714	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0002950//ceramide phosphoethanolamine synthase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0033188//sphingomyelin synthase activity;GO:0047493//ceramide cholinephosphotransferase activity"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0016310//phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0030500//regulation of bone mineralization;GO:0046513//ceramide biosynthetic process;GO:1905373//ceramide phosphoethanolamine biosynthetic process	--
ENSG00000164024	10.788	10.212	11.69	11.339	11.961	12.807	591	565	481	451	563	510	METAP1	methionyl aminopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:15789]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006417//regulation of translation;GO:0006508//proteolysis;GO:0018206//peptidyl-methionine modification;GO:0031365//N-terminal protein amino acid modification;GO:0070084//protein initiator methionine removal;GO:0070527//platelet aggregation	--
ENSG00000164031	19.288	6.494	9.565	11.252	4.402	11.257	964	601	466	345	457	481	DNAJB14	DnaJ heat shock protein family (Hsp40) member B14 [Source:HGNC Symbol;Acc:HGNC:25881]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0030544//Hsp70 protein binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034622//cellular protein-containing complex assembly;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein	--
ENSG00000164032	88.349	74.938	89.699	78.463	68.991	90.973	1587	1353	1190	1044	1047	1189	H2AZ1	H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071392//cellular response to estradiol stimulus	--
ENSG00000164035	0	0	0	0	0.014	0	0	0	0	0	1	0	EMCN	endomucin [Source:HGNC Symbol;Acc:HGNC:16041]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0001525//angiogenesis;GO:0030155//regulation of cell adhesion;GO:0061484//hematopoietic stem cell homeostasis;GO:0098609//cell-cell adhesion	--
ENSG00000164037	0.313	0.507	0.228	0.268	0.126	0.386	8	14	3	4	2	5	SLC9B1	solute carrier family 9 member B1 [Source:HGNC Symbol;Acc:HGNC:24244]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0007338//single fertilization;GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051179//localization;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000164038	18.229	15.74	15.063	13.299	12.838	14.463	1357.14	1300	863	721	851.11	826	SLC9B2	solute carrier family 9 member B2 [Source:HGNC Symbol;Acc:HGNC:25143]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0031966//mitochondrial membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0097228//sperm principal piece	GO:0005451//monovalent cation:proton antiporter activity;GO:0005515//protein binding;GO:0010348//lithium:proton antiporter activity;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051179//localization;GO:0055085//transmembrane transport;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0072583//clathrin-dependent endocytosis;GO:1902600//proton transmembrane transport;GO:2001206//positive regulation of osteoclast development	--
ENSG00000164039	32.066	31.936	30.779	25.596	25.933	31.208	1298.86	1396	997	858	1068.89	918	BDH2	3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K00019;K00019	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003858//3-hydroxybutyrate dehydrogenase activity;GO:0005515//protein binding;GO:0008667//2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0051287//NAD binding"	GO:0006629//lipid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0019290//siderophore biosynthetic process;GO:0030855//epithelial cell differentiation;GO:0042168//heme metabolic process;GO:0055072//iron ion homeostasis	--
ENSG00000164040	55.4	51.968	44.401	40.456	47.558	46.608	2237	2162	1483	1332	1568	1441	PGRMC2	progesterone receptor membrane component 2 [Source:HGNC Symbol;Acc:HGNC:16089]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015232//heme transmembrane transporter activity;GO:0020037//heme binding	GO:0015886//heme transport;GO:0043401//steroid hormone mediated signaling pathway;GO:0060612//adipose tissue development	--
ENSG00000164045	1.19	0.784	1.152	1.684	0.623	1.191	58	50	41	52	42	60	CDC25A	cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Cancer: overview;Cancer: overview;Cell growth and death;Cell growth and death;Endocrine system	ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko04218//Cellular senescence;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K06645;K06645;K06645;K06645;K06645	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0051087//chaperone binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0008283//cell population proliferation;GO:0009314//response to radiation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0034644//cellular response to UV;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051301//cell division;GO:0110032//positive regulation of G2/MI transition of meiotic cell cycle;GO:1902751//positive regulation of cell cycle G2/M phase transition	--
ENSG00000164047	0	0	0	0	0	0	0	0	0	0	0	0	CAMP	cathelicidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:1472]	Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Digestive system	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection;ko04970//Salivary secretion	K13916;K13916;K13916;K13916;K13916	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0035580//specific granule lumen;GO:0042581//specific granule;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0001530//lipopolysaccharide binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002227//innate immune response in mucosa;GO:0006952//defense response;GO:0006955//immune response;GO:0008284//positive regulation of cell population proliferation;GO:0019731//antibacterial humoral response;GO:0042119//neutrophil activation;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0045766//positive regulation of angiogenesis;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051707//response to other organism;GO:0051873//killing by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide;GO:0071224//cellular response to peptidoglycan;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000164048	5.243	4.874	5.175	5.03	4.284	4.91	303	306	262	250	225	221	ZNF589	zinc finger protein 589 [Source:HGNC Symbol;Acc:HGNC:16747]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000164049	0	0	0	0	0	0	0	0	0	0	0	0	FBXW12	F-box and WD repeat domain containing 12 [Source:HGNC Symbol;Acc:HGNC:20729]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000164050	40.969	40.358	50.308	51.897	52.8	56.726	6095	6026	5520	5711	6648	6157	PLXNB1	plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06821	GO:0002116//semaphorin receptor complex;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017154//semaphorin receptor activity;GO:0030215//semaphorin receptor binding;GO:0032794//GTPase activating protein binding	GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016477//cell migration;GO:0030334//regulation of cell migration;GO:0033689//negative regulation of osteoblast proliferation;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0043931//ossification involved in bone maturation;GO:0048812//neuron projection morphogenesis;GO:0050772//positive regulation of axonogenesis;GO:0051493//regulation of cytoskeleton organization;GO:0071526//semaphorin-plexin signaling pathway;GO:1900220//semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1904862//inhibitory synapse assembly	--
ENSG00000164051	15.156	16.222	20.064	24.753	22.146	24.626	482	528	472	570	591	580	CCDC51	coiled-coil domain containing 51 [Source:HGNC Symbol;Acc:HGNC:25714]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0034705//potassium channel complex;GO:0062157//mitochondrial ATP-gated potassium channel complex	GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0062156//mitochondrial ATP-gated potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0071805//potassium ion transmembrane transport;GO:0140141//mitochondrial potassium ion transmembrane transport	--
ENSG00000164053	3.424	3.668	3.724	3.538	3.33	3.417	194.9	252.22	194.5	174.43	196.62	154.06	ATRIP	ATR interacting protein [Source:HGNC Symbol;Acc:HGNC:33499]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10905	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070310//ATR-ATRIP complex	GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0006139//nucleobase-containing compound metabolic process;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:2000779//regulation of double-strand break repair	--
ENSG00000164054	299.502	320.854	312.81	346.231	329.09	286.401	12480	13382	9725	10705	11594	8668	SHISA5	shisa family member 5 [Source:HGNC Symbol;Acc:HGNC:30376]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10135	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0006915//apoptotic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000164056	11.075	10.169	12.395	8.703	12.373	10.664	394	396	318	224	390	297	SPRY1	sprouty RTK signaling antagonist 1 [Source:HGNC Symbol;Acc:HGNC:11269]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0000132//establishment of mitotic spindle orientation;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001759//organ induction;GO:0007275//multicellular organism development;GO:0008285//negative regulation of cell population proliferation;GO:0009966//regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048513//animal organ development;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0060449//bud elongation involved in lung branching;GO:0060940//epithelial to mesenchymal transition involved in cardiac fibroblast development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1902747//negative regulation of lens fiber cell differentiation	--
ENSG00000164061	0.133	0.198	0.143	0.159	0.193	0.079	44	66	35	39	54	19	BSN	bassoon presynaptic cytomatrix protein [Source:HGNC Symbol;Acc:HGNC:1117]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone;GO:0060076//excitatory synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0046872//metal ion binding;GO:0098882//structural constituent of presynaptic active zone	GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0035418//protein localization to synapse;GO:0048790//maintenance of presynaptic active zone structure;GO:0098693//regulation of synaptic vesicle cycle;GO:0099526//presynapse to nucleus signaling pathway;GO:1904071//presynaptic active zone assembly	--
ENSG00000164062	49.907	48.026	55.849	63.285	57.744	59.056	2228	2313	1868	2163	2289	2074	APEH	acylaminoacyl-peptide hydrolase [Source:HGNC Symbol;Acc:HGNC:586]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity;GO:0008242//omega peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006415//translational termination;GO:0006508//proteolysis;GO:0050435//amyloid-beta metabolic process	--
ENSG00000164066	2.196	2.279	1.812	1.573	1.608	2.599	359	332	239	188	214	180	INTU	inturned planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:29239]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0009986//cell surface;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001736//establishment of planar polarity;GO:0007399//nervous system development;GO:0008589//regulation of smoothened signaling pathway;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016192//vesicle-mediated transport;GO:0021513//spinal cord dorsal/ventral patterning;GO:0021915//neural tube development;GO:0030030//cell projection organization;GO:0030216//keratinocyte differentiation;GO:0030278//regulation of ossification;GO:0031069//hair follicle morphogenesis;GO:0042073//intraciliary transport;GO:0042733//embryonic digit morphogenesis;GO:0043587//tongue morphogenesis;GO:0044458//motile cilium assembly;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051782//negative regulation of cell division;GO:0060021//roof of mouth development;GO:0060173//limb development;GO:0060271//cilium assembly;GO:1902017//regulation of cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000164068	10.436	11.817	12.51	14.726	12.238	13.583	887.82	981.16	750.73	914.49	878.44	824.36	RNF123	ring finger protein 123 [Source:HGNC Symbol;Acc:HGNC:21148]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000164070	3.639	2.688	2.842	1.948	2.989	3.179	339	263	159	155	221	205	HSPA4L	heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09485	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0006457//protein folding;GO:0006986//response to unfolded protein	--
ENSG00000164073	5.491	4.439	4.036	3.897	4.099	5.24	270	236	159	137	162	200	MFSD8	major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12307	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0007040//lysosome organization;GO:0010506//regulation of autophagy;GO:0038202//TORC1 signaling;GO:0048666//neuron development;GO:0055085//transmembrane transport;GO:0097352//autophagosome maturation;GO:1905165//regulation of lysosomal protein catabolic process	--
ENSG00000164074	1.682	1.559	1.962	2.238	2.371	2.772	127	113	89	107	106	106	ABHD18	abhydrolase domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26111]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000164076	1.913	1.312	1.382	0.912	1.247	1.399	107	79	62	35	47	62	CAMKV	CaM kinase like vesicle associated [Source:HGNC Symbol;Acc:HGNC:28788]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0098978//glutamatergic synapse	GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0099159//regulation of modification of postsynaptic structure	--
ENSG00000164077	9.447	8.71	12.41	10.137	11.158	10.654	387	371	374	304	388	317	MON1A	"MON1 homolog A, secretory trafficking associated [Source:HGNC Symbol;Acc:HGNC:28207]"	-	-	-	-	GO:0005829//cytosol;GO:0035658//Mon1-Ccz1 complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006623//protein targeting to vacuole;GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000164078	7.485	7.32	7.399	6.286	6.798	7.584	715	705	530	452	563	542	MST1R	macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K05100	GO:0001725//stress fiber;GO:0005773//vacuole;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005011//macrophage colony-stimulating factor receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding	GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007338//single fertilization;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0009615//response to virus;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000164080	2.305	2.018	2.593	2.213	2.276	2.125	389	366	305	249	325	279	RAD54L2	RAD54 like 2 [Source:HGNC Symbol;Acc:HGNC:29123]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006338//chromatin remodeling;GO:0032508//DNA duplex unwinding	--
ENSG00000164081	47.97	49.422	54.954	66.217	60.056	62.199	1260	1239	1038	1271	1319	1177	TEX264	"testis expressed 264, ER-phagy receptor [Source:HGNC Symbol;Acc:HGNC:30247]"	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031093//platelet alpha granule lumen;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006281//DNA repair;GO:0006914//autophagy;GO:0006974//cellular response to DNA damage stimulus;GO:0061709//reticulophagy;GO:0106300//protein-DNA covalent cross-linking repair	--
ENSG00000164082	0	0	0	0	0	0	0	0	0	0	0	0	GRM2	glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Signal transduction;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse;ko05030//Cocaine addiction	K04605;K04605;K04605;K04605	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0097449//astrocyte projection;GO:0099055//integral component of postsynaptic membrane	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0001641//group II metabotropic glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0097110//scaffold protein binding	"GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0010467//gene expression;GO:0014047//glutamate secretion;GO:0014048//regulation of glutamate secretion;GO:0014059//regulation of dopamine secretion;GO:0023052//signaling;GO:0035095//behavioral response to nicotine;GO:0042220//response to cocaine;GO:0051896//regulation of protein kinase B signaling;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0090461//glutamate homeostasis;GO:2001023//regulation of response to drug"	--
ENSG00000164086	14.881	15.898	14.98	15.929	15.458	17.843	1035	1111	770	821	908	904	DUSP7	dual specificity phosphatase 7 [Source:HGNC Symbol;Acc:HGNC:3073]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0070371//ERK1 and ERK2 cascade	--
ENSG00000164087	2.056	2.569	2.399	2.177	2.026	1.361	80	100	72	63	68	40	POC1A	POC1 centriolar protein A [Source:HGNC Symbol;Acc:HGNC:24488]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000164088	7.455	6.443	7.283	7.678	7.76	8.879	332	291	240	240	286	296	PPM1M	"protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506]"	-	-	-	-	GO:0005634//nucleus	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000164089	0	0.031	0	0	0	0	0	1	0	0	0	0	ETNPPL	ethanolamine-phosphate phospho-lyase [Source:HGNC Symbol;Acc:HGNC:14404]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K14286;K14286	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0008483//transaminase activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0050459//ethanolamine-phosphate phospho-lyase activity	-	--
ENSG00000164091	45.211	44.294	48.356	46.59	46.981	47.094	3954	3958	3175	3068	3496	3031	WDR82	WD repeat domain 82 [Source:HGNC Symbol;Acc:HGNC:28826]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14962	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0035097//histone methyltransferase complex;GO:0048188//Set1C/COMPASS complex;GO:0072357//PTW/PP1 phosphatase complex"	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042800//histone methyltransferase activity (H3-K4 specific)	GO:0006807//nitrogen compound metabolic process;GO:0043170//macromolecule metabolic process;GO:0044238//primary metabolic process;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation	--
ENSG00000164093	0	0.028	0	0	0	0.039	0	1	0	0	0	1	PITX2	paired like homeodomain 2 [Source:HGNC Symbol;Acc:HGNC:9005]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K04686	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043021//ribonucleoprotein complex binding;GO:0051219//phosphoprotein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0009653//anatomical structure morphogenesis;GO:0035315//hair cell differentiation;GO:0035993//deltoid tuberosity development;GO:0042476//odontogenesis;GO:0043010//camera-type eye development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048536//spleen development;GO:0060126//somatotropin secreting cell differentiation;GO:0060127//prolactin secreting cell differentiation;GO:0060971//embryonic heart tube left/right pattern formation;GO:0061072//iris morphogenesis;GO:0061325//cell proliferation involved in outflow tract morphogenesis;GO:0070986//left/right axis specification"	Homeobox
ENSG00000164096	19.067	19.534	18.597	18.058	17.996	18.67	1074	1101	768	757	859	757	C4orf3	chromosome 4 open reading frame 3 [Source:HGNC Symbol;Acc:HGNC:19225]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:1901877//negative regulation of calcium ion binding;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity	--
ENSG00000164099	10.015	9.425	9.285	3.573	3.785	3.1	999	945	684	264	319	225	PRSS12	serine protease 12 [Source:HGNC Symbol;Acc:HGNC:9477]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0043083//synaptic cleft;GO:0043195//terminal bouton;GO:0045202//synapse	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006887//exocytosis;GO:0006897//endocytosis;GO:0031638//zymogen activation	--
ENSG00000164100	0.374	0.372	0.371	0.213	0.236	0.24	45	45	33	19	24	21	NDST3	N-deacetylase and N-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:7682]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02578;K02578	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0008146//sulfotransferase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0102140//heparan sulfate N-deacetylase activity	"GO:0008152//metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030210//heparin biosynthetic process"	--
ENSG00000164104	15.549	14.558	15.873	16.691	12.509	15.949	386	375	306	306	287	303	HMGB2	high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000]	-	-	-	-	GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	"GO:0000400//four-way junction DNA binding;GO:0000976//transcription cis-regulatory region binding;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008301//DNA binding, bending;GO:0019904//protein domain specific binding;GO:0042056//chemoattractant activity;GO:0044378//non-sequence-specific DNA binding, bending;GO:0050786//RAGE receptor binding;GO:0097100//supercoiled DNA binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0006265//DNA topological change;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007283//spermatogenesis;GO:0007289//spermatid nucleus differentiation;GO:0008584//male gonad development;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032075//positive regulation of nuclease activity;GO:0032392//DNA geometric change;GO:0032496//response to lipopolysaccharide;GO:0032728//positive regulation of interferon-beta production;GO:0033151//V(D)J recombination;GO:0043388//positive regulation of DNA binding;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048545//response to steroid hormone;GO:0050767//regulation of neurogenesis;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0071222//cellular response to lipopolysaccharide;GO:0072091//regulation of stem cell proliferation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors"	HMG
ENSG00000164105	11.119	11.718	12.258	11.985	10.352	12.322	253	268	206	202	199	204	SAP30	Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532]	Human Diseases	Infectious disease: viral	ko05169//Epstein-Barr virus infection	K19202	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0035914//skeletal muscle cell differentiation;GO:0052472//modulation by host of symbiont transcription;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000164106	0.072	0.103	0.098	0	0.043	0.05	6	7	6	0	3	3	SCRG1	stimulator of chondrogenesis 1 [Source:HGNC Symbol;Acc:HGNC:17036]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0044306//neuron projection terminus	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0097168//mesenchymal stem cell proliferation	--
ENSG00000164107	24.921	23.542	30.925	21.563	19.993	28.68	1437	1348	1258	921	974	1186	HAND2	heart and neural crest derivatives expressed 2 [Source:HGNC Symbol;Acc:HGNC:4808]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001525//angiogenesis;GO:0001701//in utero embryonic development;GO:0001947//heart looping;GO:0001967//suckling behavior;GO:0003007//heart morphogenesis;GO:0003219//cardiac right ventricle formation;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0003357//noradrenergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0007512//adult heart development;GO:0010463//mesenchymal cell proliferation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014032//neural crest cell development;GO:0030154//cell differentiation;GO:0032502//developmental process;GO:0034103//regulation of tissue remodeling;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043586//tongue development;GO:0045668//negative regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048485//sympathetic nervous system development;GO:0048538//thymus development;GO:0048706//embryonic skeletal system development;GO:0048935//peripheral nervous system neuron development;GO:0060021//roof of mouth development;GO:0060485//mesenchyme development;GO:0060536//cartilage morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0061032//visceral serous pericardium development;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0061325//cell proliferation involved in outflow tract morphogenesis;GO:0061371//determination of heart left/right asymmetry;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071300//cellular response to retinoic acid;GO:0071407//cellular response to organic cyclic compound;GO:1900745//positive regulation of p38MAPK cascade;GO:1903929//primary palate development;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:2000763//positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process;GO:2000764//positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis"	bHLH
ENSG00000164109	2.223	2.475	2.433	2.965	0.765	2.97	115	129	80	92	53	83	MAD2L1	mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763]	Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: viral;Cell growth and death;Cell growth and death;Endocrine system	ko05166//Human T-cell leukemia virus 1 infection;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K02537;K02537;K02537;K02537	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0033597//mitotic checkpoint complex;GO:0044615//nuclear pore nuclear basket;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle;GO:1990728//mitotic spindle assembly checkpoint MAD1-MAD2 complex"	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0000070//mitotic sister chromatid segregation;GO:0000132//establishment of mitotic spindle orientation;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045930//negative regulation of mitotic cell cycle;GO:0051301//cell division;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0051660//establishment of centrosome localization;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1904667//negative regulation of ubiquitin protein ligase activity	--
ENSG00000164111	374.357	381.461	376.644	337.119	333.786	336.163	12717	13023	9451	8484	9581	8310	ANXA5	annexin A5 [Source:HGNC Symbol;Acc:HGNC:543]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072563//endothelial microparticle	GO:0004859//phospholipase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding	GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010033//response to organic substance;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0050819//negative regulation of coagulation	--
ENSG00000164112	12.573	14.191	12.316	11.571	10.732	11.815	602	679	433	408	432	410	SMIM43	small integral membrane protein 43 [Source:HGNC Symbol;Acc:HGNC:55077]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164113	0	0	0	0	0	0	0	0	0	0	0	0	ADAD1	adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0004000//adenosine deaminase activity;GO:0008251//tRNA-specific adenosine deaminase activity	GO:0006382//adenosine to inosine editing;GO:0006396//RNA processing;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation	--
ENSG00000164114	7.381	6.499	5.041	2.348	3.68	4.551	709	506	324	166	272	288	MAP9	microtubule associated protein 9 [Source:HGNC Symbol;Acc:HGNC:26118]	-	-	-	-	GO:0000235//astral microtubule;GO:0005737//cytoplasm;GO:0005818//aster;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030424//axon;GO:0051233//spindle midzone;GO:0072686//mitotic spindle;GO:1990023//mitotic spindle midzone	GO:0008017//microtubule binding	GO:0000281//mitotic cytokinesis;GO:0007049//cell cycle;GO:0046602//regulation of mitotic centrosome separation;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0090307//mitotic spindle assembly;GO:1902412//regulation of mitotic cytokinesis	--
ENSG00000164116	1.019	0.795	0.805	0.557	0.816	0.658	120	85	57	44	63	55	GUCY1A1	guanylate cyclase 1 soluble subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:4685]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Global and overview maps;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Immune system;Environmental adaptation;Digestive system;Cellular community - eukaryotes;Endocrine system;Nervous system	ko01100//Metabolic pathways;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04611//Platelet activation;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04540//Gap junction;ko04924//Renin secretion;ko04730//Long-term depression	K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318;K12318	"GO:0005737//cytoplasm;GO:0008074//guanylate cyclase complex, soluble;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse"	GO:0000166//nucleotide binding;GO:0004383//guanylate cyclase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0020037//heme binding;GO:0038023//signaling receptor activity	"GO:0006182//cGMP biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010750//positive regulation of nitric oxide mediated signal transduction;GO:0035556//intracellular signal transduction;GO:0060087//relaxation of vascular associated smooth muscle;GO:0098925//retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission"	--
ENSG00000164117	7.548	7.485	6.594	7.73	7.119	6.8	310	309	200	234	247	200	FBXO8	F-box protein 8 [Source:HGNC Symbol;Acc:HGNC:13587]	-	-	-	-	GO:0000151//ubiquitin ligase complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000164118	1.277	1.184	1.236	1.788	1.081	1.34	108	90	57	74	77	72	CEP44	centrosomal protein 44 [Source:HGNC Symbol;Acc:HGNC:29356]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007098//centrosome cycle;GO:0007099//centriole replication;GO:0010457//centriole-centriole cohesion	--
ENSG00000164120	1.177	0.922	1.222	1.261	1.14	1.402	54	50	37	41	39	44	HPGD	15-hydroxyprostaglandin dehydrogenase [Source:HGNC Symbol;Acc:HGNC:5154]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K00069	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	"GO:0004957//prostaglandin E receptor activity;GO:0016404//15-hydroxyprostaglandin dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0051287//NAD binding;GO:0070403//NAD+ binding"	GO:0001822//kidney development;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007565//female pregnancy;GO:0007567//parturition;GO:0019372//lipoxygenase pathway;GO:0030728//ovulation;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0045471//response to ethanol;GO:0045786//negative regulation of cell cycle;GO:0070493//thrombin-activated receptor signaling pathway;GO:0097070//ductus arteriosus closure;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905828//regulation of prostaglandin catabolic process	--
ENSG00000164122	0.102	0.061	0	0	0	0.075	6	3	0	0	0	2	ASB5	ankyrin repeat and SOCS box containing 5 [Source:HGNC Symbol;Acc:HGNC:17180]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification;GO:0045732//positive regulation of protein catabolic process	--
ENSG00000164123	0	0	0	0	0	0.052	0	0	0	0	0	1	C4orf45	chromosome 4 open reading frame 45 [Source:HGNC Symbol;Acc:HGNC:26342]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164124	3.837	4.523	3.805	3.602	4.839	3.866	244	269	155	158	213	167	TMEM144	transmembrane protein 144 [Source:HGNC Symbol;Acc:HGNC:25633]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015144//carbohydrate transmembrane transporter activity	GO:0034219//carbohydrate transmembrane transport	--
ENSG00000164125	5.733	4.175	2.825	3.128	3.566	3.012	584	431	214	237	308	215	GASK1B	golgi associated kinase 1B [Source:HGNC Symbol;Acc:HGNC:25312]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164128	0.262	0.244	0.366	0.519	0.413	0.192	15	14	11	22	20	8	NPY1R	neuropeptide Y receptor Y1 [Source:HGNC Symbol;Acc:HGNC:7956]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K04204;K04204;K04204	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001601//peptide YY receptor activity;GO:0001602//pancreatic polypeptide receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding	"GO:0003151//outflow tract morphogenesis;GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007626//locomotory behavior;GO:0007631//feeding behavior;GO:0008217//regulation of blood pressure;GO:0019233//sensory perception of pain;GO:0040014//regulation of multicellular organism growth"	--
ENSG00000164129	0	0.068	0.046	0	0	0.047	0	2	1	0	0	1	NPY5R	neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04207	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse	GO:0001601//peptide YY receptor activity;GO:0001602//pancreatic polypeptide receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity	"GO:0002675//positive regulation of acute inflammatory response;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0003151//outflow tract morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0014050//negative regulation of glutamate secretion;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0042755//eating behavior;GO:0043066//negative regulation of apoptotic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0060112//generation of ovulation cycle rhythm;GO:0070374//positive regulation of ERK1 and ERK2 cascade"	--
ENSG00000164134	5.622	3.875	4.025	2.711	2.985	3.661	719.71	498.56	379.99	257.15	323	340.63	NAA15	"N-alpha-acetyltransferase 15, NatA auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:30782]"	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031415//NatA complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0016407//acetyltransferase activity;GO:0043022//ribosome binding	"GO:0001525//angiogenesis;GO:0006474//N-terminal protein amino acid acetylation;GO:0017196//N-terminal peptidyl-methionine acetylation;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization"	--
ENSG00000164136	0.542	0.097	0.37	0.492	0.394	0.451	21	5	15	19	19	12	IL15	interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Immune disease;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04630//JAK-STAT signaling pathway;ko05323//Rheumatoid arthritis;ko04672//Intestinal immune network for IgA production;ko04668//TNF signaling pathway	K05433;K05433;K05433;K05433;K05433;K05433;K05433	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016607//nuclear speck	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005515//protein binding	GO:0001819//positive regulation of cytokine production;GO:0001866//NK T cell proliferation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0007267//cell-cell signaling;GO:0007568//aging;GO:0008284//positive regulation of cell population proliferation;GO:0014732//skeletal muscle atrophy;GO:0030212//hyaluronan metabolic process;GO:0030225//macrophage differentiation;GO:0031667//response to nutrient levels;GO:0032740//positive regulation of interleukin-17 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0034105//positive regulation of tissue remodeling;GO:0035723//interleukin-15-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042119//neutrophil activation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045062//extrathymic T cell selection;GO:0045580//regulation of T cell differentiation;GO:0048469//cell maturation;GO:0048535//lymph node development;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050691//regulation of defense response to virus by host;GO:0050729//positive regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766//positive regulation of phagocytosis;GO:0050778//positive regulation of immune response;GO:0071305//cellular response to vitamin D;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1904100//positive regulation of protein O-linked glycosylation	--
ENSG00000164142	7.834	7.007	7.927	7.324	5.743	7.556	1562	1341	1172	951	1159	1170	FHIP1A	FHF complex subunit HOOK interacting protein 1A [Source:HGNC Symbol;Acc:HGNC:34237]	-	-	-	-	-	-	GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000164144	10.816	7.698	9.584	8.677	8.624	9.563	601	476	394	385	428	403	ARFIP1	ADP ribosylation factor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21496]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0019904//protein domain specific binding;GO:0070273//phosphatidylinositol-4-phosphate binding	"GO:0006886//intracellular protein transport;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0050708//regulation of protein secretion;GO:1905280//negative regulation of retrograde transport, endosome to Golgi"	--
ENSG00000164151	8.349	5.286	5.186	3.702	3.893	5.047	1342	874	630	451	541	604	ICE1	interactor of little elongation complex ELL subunit 1 [Source:HGNC Symbol;Acc:HGNC:29154]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0035327//transcriptionally active chromatin;GO:0035363//histone locus body	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0031334//positive regulation of protein-containing complex assembly;GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0090316//positive regulation of intracellular protein transport	--
ENSG00000164161	0.029	0.029	0	0.078	0.006	0	2	5	0	3	1	0	HHIP	hedgehog interacting protein [Source:HGNC Symbol;Acc:HGNC:14866]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04024//cAMP signaling pathway;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K06231;K06231;K06231;K06231	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0060170//ciliary membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0097108//hedgehog family protein binding	GO:0007165//signal transduction;GO:0007405//neuroblast proliferation;GO:0009887//animal organ morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0009968//negative regulation of signal transduction;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis	--
ENSG00000164162	4.362	4.532	5.5	6.14	5.963	4.416	98	97.88	87.94	99.84	115	72.84	ANAPC10	anaphase promoting complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:24077]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03357;K03357;K03357;K03357;K03357	GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	-	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000164163	20.519	16.729	15.548	12.409	16.778	17.658	1310	1155	793	724	880	835	ABCE1	ATP binding cassette subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:69]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0043024//ribosomal small subunit binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0060698//endoribonuclease inhibitor activity"	GO:0000054//ribosomal subunit export from nucleus;GO:0006413//translational initiation;GO:0006415//translational termination;GO:0006417//regulation of translation;GO:0060702//negative regulation of endoribonuclease activity	--
ENSG00000164164	18.668	14.263	16.183	12.522	14.148	15.47	2635	1966	1666	1296	1611	1632	OTUD4	OTU deubiquitinase 4 [Source:HGNC Symbol;Acc:HGNC:24949]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0060090//molecular adaptor activity;GO:0061578//Lys63-specific deubiquitinase activity	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1901537//positive regulation of DNA demethylation;GO:1903093//regulation of protein K48-linked deubiquitination;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway	--
ENSG00000164167	7.152	6.111	7.987	8.19	5.437	8.931	93	78	74	80	62	80	LSM6	"LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17017]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12625;K12625	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0120115//Lsm2-8 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0008033//tRNA processing;GO:0008380//RNA splicing;GO:0030490//maturation of SSU-rRNA"	--
ENSG00000164168	16.63	12.114	16.841	15.535	15.611	15.057	1083	918	703	607	690	810	TMEM184C	transmembrane protein 184C [Source:HGNC Symbol;Acc:HGNC:25587]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164169	5.215	4.128	4.467	4.525	4.577	4.092	361	281	217	235	263	203	PRMT9	protein arginine methyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:25099]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity	"GO:0006397//mRNA processing;GO:0018216//peptidyl-arginine methylation;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0032259//methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0035247//peptidyl-arginine omega-N-methylation"	--
ENSG00000164171	0.843	0.483	0.127	0.155	0.211	0.257	105	79	14	14	29	21	ITGA2	integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cell motility;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Immune system;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko04611//Platelet activation;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481;K06481	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0034666//integrin alpha2-beta1 complex;GO:0042995//cell projection;GO:0043679//axon terminus;GO:0045178//basal part of cell;GO:0048471//perinuclear region of cytoplasm	GO:0001540//amyloid-beta binding;GO:0001618//virus receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0038064//collagen receptor activity;GO:0043236//laminin binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0098639//collagen binding involved in cell-matrix adhesion	"GO:0001666//response to hypoxia;GO:0002687//positive regulation of leukocyte migration;GO:0006929//substrate-dependent cell migration;GO:0006971//hypotonic response;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007565//female pregnancy;GO:0007596//blood coagulation;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009887//animal organ morphogenesis;GO:0010634//positive regulation of epithelial cell migration;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0014070//response to organic cyclic compound;GO:0014075//response to amine;GO:0014850//response to muscle activity;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030198//extracellular matrix organization;GO:0030879//mammary gland development;GO:0031346//positive regulation of cell projection organization;GO:0031589//cell-substrate adhesion;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033343//positive regulation of collagen binding;GO:0033591//response to L-ascorbic acid;GO:0033627//cell adhesion mediated by integrin;GO:0038065//collagen-activated signaling pathway;GO:0042060//wound healing;GO:0043388//positive regulation of DNA binding;GO:0043589//skin morphogenesis;GO:0045184//establishment of protein localization;GO:0045727//positive regulation of translation;GO:0045785//positive regulation of cell adhesion;GO:0045987//positive regulation of smooth muscle contraction;GO:0046718//viral entry into host cell;GO:0048041//focal adhesion assembly;GO:0048333//mesodermal cell differentiation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0050927//positive regulation of positive chemotaxis;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051971//positive regulation of transmission of nerve impulse;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0070365//hepatocyte differentiation;GO:0071107//response to parathyroid hormone;GO:0071260//cellular response to mechanical stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0098609//cell-cell adhesion"	--
ENSG00000164172	15.2	11.549	14.766	13.837	10.491	15.117	609	500	397	384	367	418	MOCS2	molybdenum cofactor synthesis 2 [Source:HGNC Symbol;Acc:HGNC:7193]	Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Metabolism of cofactors and vitamins;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00790//Folate biosynthesis;ko04122//Sulfur relay system	K03635;K03635;K03635	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0019008//molybdopterin synthase complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030366//molybdopterin synthase activity	GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0032324//molybdopterin cofactor biosynthetic process	--
ENSG00000164175	81	80.079	93.056	110.79	100.501	107.079	3077	3207	2684	3184	3202	3045	SLC45A2	solute carrier family 45 member 2 [Source:HGNC Symbol;Acc:HGNC:16472]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033162//melanosome membrane	GO:0008506//sucrose:proton symporter activity	GO:0007601//visual perception;GO:0015770//sucrose transport;GO:0042438//melanin biosynthetic process;GO:0048066//developmental pigmentation;GO:0050896//response to stimulus	--
ENSG00000164176	30.697	24.431	18.842	10.873	12.753	10.697	2918	2360	1333	776	1042	753	EDIL3	EGF like repeats and discoidin domains 3 [Source:HGNC Symbol;Acc:HGNC:3173]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0010811//positive regulation of cell-substrate adhesion	--
ENSG00000164180	5.016	4.288	3.699	4.088	3.943	5.775	331	277	189	209	237	250	TMEM161B	transmembrane protein 161B [Source:HGNC Symbol;Acc:HGNC:28483]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003676//nucleic acid binding	GO:0002027//regulation of heart rate;GO:0015074//DNA integration;GO:0098901//regulation of cardiac muscle cell action potential	--
ENSG00000164181	23.837	21.68	20.531	28.272	25.423	33.82	1650	1521	1142	1531	1506	1688	ELOVL7	ELOVL fatty acid elongase 7 [Source:HGNC Symbol;Acc:HGNC:26292]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10250;K10250;K10250;K10250	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process"	--
ENSG00000164182	6.545	7.912	6.003	6.409	6.044	8.524	96	120	67	72	77	96	NDUFAF2	NADH:ubiquinone oxidoreductase complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:28086]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18160	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000164185	0	0.174	0.068	0.067	0	0.034	0	7	2	2	0	1	ZNF474	zinc finger protein 474 [Source:HGNC Symbol;Acc:HGNC:23245]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000164187	4.972	3.676	3.66	2.518	3.509	3.633	837	622	455	314	499	445	LMBRD2	LMBR1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25287]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0071875//adrenergic receptor signaling pathway	--
ENSG00000164188	0.456	0.383	0.28	0.084	0.091	0.205	35	33	11	6	5	8	RANBP3L	RAN binding protein 3 like [Source:HGNC Symbol;Acc:HGNC:26353]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046332//SMAD binding	GO:0006611//protein export from nucleus;GO:0045663//positive regulation of myoblast differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity;GO:1901706//mesenchymal cell differentiation involved in bone development	--
ENSG00000164190	4.363	2.181	2.034	1.157	2.025	1.89	832	416	289	171	320	279	NIPBL	NIPBL cohesin loading factor [Source:HGNC Symbol;Acc:HGNC:28862]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0032039//integrator complex;GO:0032116//SMC loading complex;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0090694//Scc2-Scc4 cohesin loading complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0036033//mediator complex binding;GO:0042826//histone deacetylase binding;GO:0047485//protein N-terminus binding;GO:0070087//chromo shadow domain binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0003007//heart morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0007420//brain development;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0009790//embryo development;GO:0010468//regulation of gene expression;GO:0019827//stem cell population maintenance;GO:0031065//positive regulation of histone deacetylation;GO:0034087//establishment of mitotic sister chromatid cohesion;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0034613//cellular protein localization;GO:0035115//embryonic forelimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0035261//external genitalia morphogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0042471//ear morphogenesis;GO:0042634//regulation of hair cycle;GO:0045444//fat cell differentiation;GO:0045778//positive regulation of ossification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0048557//embryonic digestive tract morphogenesis;GO:0048565//digestive tract development;GO:0048589//developmental growth;GO:0048592//eye morphogenesis;GO:0048638//regulation of developmental growth;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0050890//cognition;GO:0060325//face morphogenesis;GO:0061010//gall bladder development;GO:0061038//uterus morphogenesis;GO:0061780//mitotic cohesin loading;GO:0071169//establishment of protein localization to chromatin;GO:0071481//cellular response to X-ray;GO:0071921//cohesin loading;GO:1990414//replication-born double-strand break repair via sister chromatid exchange;GO:2001224//positive regulation of neuron migration"	--
ENSG00000164197	3.686	4.074	2.719	2.449	2.547	3.78	340	287	177	154	217	217	RNF180	ring finger protein 180 [Source:HGNC Symbol;Acc:HGNC:27752]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane	GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0030534//adult behavior;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042415//norepinephrine metabolic process;GO:0042428//serotonin metabolic process;GO:0050790//regulation of catalytic activity;GO:1901360//organic cyclic compound metabolic process	--
ENSG00000164199	3.272	3.412	3.984	2.728	2.692	3.709	336	240	204	157	237	245	ADGRV1	adhesion G protein-coupled receptor V1 [Source:HGNC Symbol;Acc:HGNC:17416]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0002141//stereocilia ankle link;GO:0002142//stereocilia ankle link complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0060171//stereocilium membrane;GO:0070062//extracellular exosome;GO:1990075//periciliary membrane compartment;GO:1990696//USH2 complex	GO:0001965//G-protein alpha-subunit binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0010855//adenylate cyclase inhibitor activity;GO:0016787//hydrolase activity	GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0010739//positive regulation of protein kinase A signaling;GO:0030501//positive regulation of bone mineralization;GO:0031647//regulation of protein stability;GO:0045184//establishment of protein localization;GO:0045494//photoreceptor cell maintenance;GO:0048496//maintenance of animal organ identity;GO:0048839//inner ear development;GO:0050877//nervous system process;GO:0050896//response to stimulus;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0060122//inner ear receptor cell stereocilium organization;GO:0071277//cellular response to calcium ion;GO:0090037//positive regulation of protein kinase C signaling;GO:0097264//self proteolysis;GO:0098609//cell-cell adhesion	--
ENSG00000164209	19.082	12.549	12.812	10.119	12.206	13.631	1398	1014	707	646	776	770	SLC25A46	solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0000266//mitochondrial fission;GO:0000422//autophagy of mitochondrion;GO:0006839//mitochondrial transport;GO:0007005//mitochondrion organization;GO:0007416//synapse assembly;GO:0008535//respiratory chain complex IV assembly;GO:0016358//dendrite development;GO:0021554//optic nerve development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0022011//myelination in peripheral nervous system;GO:0031987//locomotion involved in locomotory behavior;GO:0042407//cristae formation;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0055091//phospholipid homeostasis;GO:0061564//axon development;GO:0065003//protein-containing complex assembly;GO:0090149//mitochondrial membrane fission	--
ENSG00000164211	8.659	6.671	7.39	9.613	8.216	10.682	601	427	420	451	482	516	STARD4	StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0120020//cholesterol transfer activity	GO:0006869//lipid transport;GO:0010873//positive regulation of cholesterol esterification;GO:0010879//cholesterol transport involved in cholesterol storage;GO:0032367//intracellular cholesterol transport;GO:0070508//cholesterol import;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0120009//intermembrane lipid transfer	--
ENSG00000164219	4.17	2.396	2.657	2.916	2.393	2.97	352	262	188	186	201	203	PGGT1B	protein geranylgeranyltransferase type I subunit beta [Source:HGNC Symbol;Acc:HGNC:8895]	-	-	-	-	GO:0005953//CAAX-protein geranylgeranyltransferase complex	GO:0003824//catalytic activity;GO:0004659//prenyltransferase activity;GO:0004661//protein geranylgeranyltransferase activity;GO:0004662//CAAX-protein geranylgeranyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0018342//protein prenylation;GO:0018344//protein geranylgeranylation	--
ENSG00000164220	17.828	16.191	15.11	7.144	8.377	8.417	1231	1147	738	357	476	397	F2RL2	coagulation factor II thrombin receptor like 2 [Source:HGNC Symbol;Acc:HGNC:3539]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko04610//Complement and coagulation cascades	K04235;K04235	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032991//protein-containing complex	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0015057//thrombin-activated receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009611//response to wounding;GO:0030168//platelet activation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0070493//thrombin-activated receptor signaling pathway	--
ENSG00000164221	1.596	0.897	1.161	0.818	0.817	1.29	78	43	42	30	33	42	CCDC112	coiled-coil domain containing 112 [Source:HGNC Symbol;Acc:HGNC:28599]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164236	0.181	0.09	0.068	0.081	0.107	0.076	36	18	10	12	18	11	ANKRD33B	ankyrin repeat domain 33B [Source:HGNC Symbol;Acc:HGNC:35240]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164237	3.059	3.068	3.203	3.628	3.166	2.434	247	249	191	217	216	143	CMBL	carboxymethylenebutenolidase homolog [Source:HGNC Symbol;Acc:HGNC:25090]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0016787//hydrolase activity	GO:0006805//xenobiotic metabolic process	--
ENSG00000164241	1.001	1.131	2.283	1.52	1.184	1.48	28	25	23	22	21	23	C5orf63	chromosome 5 open reading frame 63 [Source:HGNC Symbol;Acc:HGNC:40051]	-	-	-	-	-	-	-	--
ENSG00000164244	19.021	17.385	19.324	16.016	17.851	18.185	1831	1696	1384	1150	1464	1284	PRRC1	proline rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28164]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding	GO:0034199//activation of protein kinase A activity	--
ENSG00000164251	2.208	1.945	1.825	2.025	1.99	1.863	131	116	80	89	90	54	F2RL1	F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: parasitic;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko05143//African trypanosomiasis;ko04750//Inflammatory mediator regulation of TRP channels	K04234;K04234;K04234	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031143//pseudopodium	GO:0001965//G-protein alpha-subunit binding;GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015057//thrombin-activated receptor activity;GO:0031681//G-protein beta-subunit binding;GO:0038023//signaling receptor activity	"GO:0002286//T cell activation involved in immune response;GO:0002376//immune system process;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0003104//positive regulation of glomerular filtration;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007596//blood coagulation;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030193//regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0030836//positive regulation of actin filament depolymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0032682//negative regulation of chemokine production;GO:0032722//positive regulation of chemokine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032930//positive regulation of superoxide anion generation;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0034140//negative regulation of toll-like receptor 3 signaling pathway;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0042119//neutrophil activation;GO:0042311//vasodilation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043311//positive regulation of eosinophil degranulation;GO:0043547//positive regulation of GTPase activity;GO:0045087//innate immune response;GO:0045217//cell-cell junction maintenance;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046328//regulation of JNK cascade;GO:0046329//negative regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0050900//leukocyte migration;GO:0050921//positive regulation of chemotaxis;GO:0050927//positive regulation of positive chemotaxis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051607//defense response to virus;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0061028//establishment of endothelial barrier;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070493//thrombin-activated receptor signaling pathway;GO:0070661//leukocyte proliferation;GO:0070963//positive regulation of neutrophil mediated killing of gram-negative bacterium;GO:0097029//mature conventional dendritic cell differentiation;GO:1900135//positive regulation of renin secretion into blood stream;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production"	--
ENSG00000164252	8.299	7.903	6.364	5.181	6.678	5.316	772.88	723.8	424.35	357.41	525.45	360.25	AGGF1	angiogenic factor with G-patch and FHA domains 1 [Source:HGNC Symbol;Acc:HGNC:24684]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003676//nucleic acid binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007155//cell adhesion;GO:0030154//cell differentiation;GO:0045766//positive regulation of angiogenesis	--
ENSG00000164253	9.387	9.185	7.952	8.919	8.534	8.603	463	423	257	243	335	277	WDR41	WD repeat domain 41 [Source:HGNC Symbol;Acc:HGNC:25601]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04140//Autophagy - animal	K23610;K23610;K23610	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0032045//guanyl-nucleotide exchange factor complex;GO:1990316//Atg1/ULK1 kinase complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0043547//positive regulation of GTPase activity;GO:0045920//negative regulation of exocytosis;GO:0050777//negative regulation of immune response	--
ENSG00000164256	0	0	0	0	0	0	0	0	0	0	0	0	PRDM9	PR/SET domain 9 [Source:HGNC Symbol;Acc:HGNC:13994]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K20796;K20796	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0010844//recombination hotspot binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0006311//meiotic gene conversion;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007129//homologous chromosome pairing at meiosis;GO:0007292//female gamete generation;GO:0010468//regulation of gene expression;GO:0010845//positive regulation of reciprocal meiotic recombination;GO:0016571//histone methylation;GO:0016584//nucleosome positioning;GO:0032259//methylation;GO:0043066//negative regulation of apoptotic process;GO:0044648//histone H3-K4 dimethylation;GO:0048232//male gamete generation;GO:0051321//meiotic cell cycle;GO:0051567//histone H3-K9 methylation;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0097198//histone H3-K36 trimethylation;GO:0097676//histone H3-K36 dimethylation;GO:0097692//histone H3-K4 monomethylation;GO:1905437//positive regulation of histone H3-K4 trimethylation;GO:1905516//positive regulation of fertilization;GO:1990918//double-strand break repair involved in meiotic recombination;GO:2001255//positive regulation of histone H3-K36 trimethylation"	zf-C2H2
ENSG00000164258	19.849	18.086	18.578	20.174	21.158	19.504	276	252	191	208	249	197	NDUFS4	NADH:ubiquinone oxidoreductase subunit S4 [Source:HGNC Symbol;Acc:HGNC:7711]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937;K03937	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0001932//regulation of protein phosphorylation;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007420//brain development;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0045333//cellular respiration;GO:0048146//positive regulation of fibroblast proliferation;GO:0051591//response to cAMP;GO:0072593//reactive oxygen species metabolic process"	--
ENSG00000164265	0	0.186	0	0	0	0	0	2	0	0	0	0	SCGB3A2	secretoglobin family 3A member 2 [Source:HGNC Symbol;Acc:HGNC:18391]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0071682//endocytic vesicle lumen	-	-	--
ENSG00000164266	0	0	0	0	0	0	0	0	0	0	0	0	SPINK1	serine peptidase inhibitor Kazal type 1 [Source:HGNC Symbol;Acc:HGNC:11244]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010466//negative regulation of peptidase activity;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:0031667//response to nutrient levels;GO:0045471//response to ethanol;GO:0048240//sperm capacitation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0060046//regulation of acrosome reaction;GO:0071375//cellular response to peptide hormone stimulus;GO:0090187//positive regulation of pancreatic juice secretion;GO:0090277//positive regulation of peptide hormone secretion;GO:0090281//negative regulation of calcium ion import;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000164270	0	0	0	0	0	0	0	0	0	0	0	0	HTR4	5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse	K04160;K04160;K04160;K04160	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0032098//regulation of appetite;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000164283	0	0	0	0	0	0	0	0	0	0	0	0	ESM1	endothelial cell specific molecule 1 [Source:HGNC Symbol;Acc:HGNC:3466]	-	-	-	-	GO:0005576//extracellular region	GO:0005171//hepatocyte growth factor receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0002040//sprouting angiogenesis;GO:0008284//positive regulation of cell population proliferation;GO:1902204//positive regulation of hepatocyte growth factor receptor signaling pathway	--
ENSG00000164284	1.733	2.21	1.608	1.15	1.306	2.538	129	139	99	71	92	154	GRPEL2	"GrpE like 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21060]"	-	-	-	-	"GO:0001405//PAM complex, Tim23 associated import motor;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005759//mitochondrial matrix"	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0006886//intracellular protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000164287	5.287	6.79	4.508	1.286	1.233	0.666	315	417	197	54	64	30	CDC20B	cell division cycle 20B [Source:HGNC Symbol;Acc:HGNC:24222]	-	-	-	-	GO:0005680//anaphase-promoting complex	GO:0005515//protein binding;GO:0010997//anaphase-promoting complex binding;GO:0097027//ubiquitin-protein transferase activator activity;GO:1990757//ubiquitin ligase activator activity	GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:1905786//positive regulation of anaphase-promoting complex-dependent catabolic process	--
ENSG00000164291	7.365	5.895	5.872	5.364	6.281	7.333	450	386.02	300	250	336	367	ARSK	arylsulfatase family member K [Source:HGNC Symbol;Acc:HGNC:25239]	-	-	-	-	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005788//endoplasmic reticulum lumen	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0015024//glucuronate-2-sulfatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000164292	81.352	64.763	66.289	45.397	55.442	52.624	8352	6721	5051	3458	4677	3904	RHOBTB3	Rho related BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18757]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding	"GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0008584//male gonad development;GO:0016192//vesicle-mediated transport;GO:0016477//cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000164294	31.111	28.573	26.537	24.212	21.703	25.388	1923	1682	1127	940	1077	1106	GPX8	glutathione peroxidase 8 (putative) [Source:HGNC Symbol;Acc:HGNC:33100]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006979//response to oxidative stress;GO:0034599//cellular response to oxidative stress;GO:0098869//cellular oxidant detoxification	--
ENSG00000164296	3.532	2.841	2.7	3.373	2.559	2.981	223	176	131	157	132	137	TIGD6	tigger transposable element derived 6 [Source:HGNC Symbol;Acc:HGNC:18332]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding	-	--
ENSG00000164299	0	0	0	0	0	0	0	0	0	0	0	0	SPZ1	spermatogenic leucine zipper 1 [Source:HGNC Symbol;Acc:HGNC:30721]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000164300	5.757	6.508	7.435	6.42	6.495	7.45	770	858	718	636	721	725	SERINC5	serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0015194//L-serine transmembrane transporter activity	GO:0002376//immune system process;GO:0006564//L-serine biosynthetic process;GO:0006629//lipid metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0006665//sphingolipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0009597//detection of virus;GO:0015825//L-serine transport;GO:0042552//myelination;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:1904219//positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;GO:1904222//positive regulation of serine C-palmitoyltransferase activity	--
ENSG00000164303	0	0.037	0.017	0	0.015	0	0	3	1	0	1	0	ENPP6	ectonucleotide pyrophosphatase/phosphodiesterase 6 [Source:HGNC Symbol;Acc:HGNC:23409]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K08743;K08743	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047390//glycerophosphocholine cholinephosphodiesterase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019695//choline metabolic process;GO:0046475//glycerophospholipid catabolic process	--
ENSG00000164304	0.017	0.108	0	0.023	0	0	1	4	0	1	0	0	CAGE1	cancer antigen 1 [Source:HGNC Symbol;Acc:HGNC:21622]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164305	13.159	13.667	11.715	11.3	9.824	11.955	677	658	458	426	443	457	CASP3	caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Endocrine and metabolic disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Nervous system;Signal transduction;Infectious disease: parasitic;Endocrine and metabolic disease;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: bacterial;Drug resistance: antineoplastic;Cell growth and death;Infectious disease: bacterial;Infectious disease: bacterial;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05416//Viral myocarditis;ko04726//Serotonergic synapse;ko04668//TNF signaling pathway;ko05145//Toxoplasmosis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04657//IL-17 signaling pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko05133//Pertussis;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187;K02187	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031264//death-inducing signaling complex;GO:0043025//neuronal cell body;GO:0045121//membrane raft	GO:0002020//protease binding;GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016005//phospholipase A2 activator activity;GO:0016787//hydrolase activity;GO:0044877//protein-containing complex binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0001554//luteolysis;GO:0001666//response to hypoxia;GO:0001782//B cell homeostasis;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007413//axonal fasciculation;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0007611//learning or memory;GO:0008627//intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0009611//response to wounding;GO:0009749//response to glucose;GO:0010033//response to organic substance;GO:0010038//response to metal ion;GO:0010165//response to X-ray;GO:0014070//response to organic cyclic compound;GO:0016241//regulation of macroautophagy;GO:0016485//protein processing;GO:0021766//hippocampus development;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0030220//platelet formation;GO:0030889//negative regulation of B cell proliferation;GO:0031647//regulation of protein stability;GO:0032025//response to cobalt ion;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0034349//glial cell apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0035094//response to nicotine;GO:0035556//intracellular signal transduction;GO:0042060//wound healing;GO:0042542//response to hydrogen peroxide;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043200//response to amino acid;GO:0043525//positive regulation of neuron apoptotic process;GO:0045165//cell fate commitment;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045786//negative regulation of cell cycle;GO:0046007//negative regulation of activated T cell proliferation;GO:0046677//response to antibiotic;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0051384//response to glucocorticoid;GO:0051402//neuron apoptotic process;GO:0061713//anterior neural tube closure;GO:0071310//cellular response to organic substance;GO:0071407//cellular response to organic cyclic compound;GO:0071887//leukocyte apoptotic process;GO:0072734//cellular response to staurosporine;GO:0097190//apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000164306	3.052	2.827	2.837	2.83	2.126	2.286	131.58	118.35	93.4	93.6	80.78	68.7	PRIMPOL	primase and DNA directed polymerase [Source:HGNC Symbol;Acc:HGNC:26575]	-	-	-	-	GO:0005634//nucleus;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003682//chromatin binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003896//DNA primase activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	"GO:0006264//mitochondrial DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0019985//translesion synthesis;GO:0031297//replication fork processing;GO:0042276//error-prone translesion synthesis;GO:0043504//mitochondrial DNA repair;GO:0062176//R-loop disassembly"	--
ENSG00000164307	10.65	13.721	10.588	10.634	11.636	9.956	935.76	991	677	630.49	709	584	ERAP1	endoplasmic reticulum aminopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:18173]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0005151//interleukin-1, type II receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity"	GO:0001525//angiogenesis;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0009617//response to bacterium;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0043171//peptide catabolic process;GO:0045088//regulation of innate immune response;GO:0045444//fat cell differentiation;GO:0045766//positive regulation of angiogenesis	--
ENSG00000164308	1.814	2.468	1.385	0.82	1.317	1.379	172	139	98	62	79	67	ERAP2	endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0043171//peptide catabolic process	--
ENSG00000164309	0.157	0.127	0.071	0.051	0.106	0.087	42	34	14	10	24	17	CMYA5	cardiomyopathy associated 5 [Source:HGNC Symbol;Acc:HGNC:14305]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0016607//nuclear speck;GO:0031430//M band;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000164318	0	0.181	0	0.1	0	0.081	0	4	0	2	0	1	EGFLAM	"EGF like, fibronectin type III and laminin G domains [Source:HGNC Symbol;Acc:HGNC:26810]"	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005614//interstitial matrix;GO:0009986//cell surface;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0042995//cell projection;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0048786//presynaptic active zone	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding	GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0030198//extracellular matrix organization	--
ENSG00000164323	14.777	12.327	11.723	10.963	12.092	14.26	1382	1101	861	720	882	854	CFAP97	cilia and flagella associated protein 97 [Source:HGNC Symbol;Acc:HGNC:29276]	-	-	-	-	-	-	GO:0007283//spermatogenesis	--
ENSG00000164325	0	0	0	0	0	0	0	0	0	0	0	0	TMEM174	transmembrane protein 174 [Source:HGNC Symbol;Acc:HGNC:28187]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000164326	0	0	0	0	0.071	0	0	0	0	0	1	0	CARTPT	CART prepropeptide [Source:HGNC Symbol;Acc:HGNC:24323]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0045202//synapse	GO:0003674//molecular_function;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding	GO:0001678//cellular glucose homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0008343//adult feeding behavior;GO:0009267//cellular response to starvation;GO:0032099//negative regulation of appetite;GO:0032812//positive regulation of epinephrine secretion;GO:0032922//circadian regulation of gene expression;GO:0043410//positive regulation of MAPK cascade;GO:0045671//negative regulation of osteoclast differentiation;GO:0045777//positive regulation of blood pressure;GO:0045779//negative regulation of bone resorption;GO:0045860//positive regulation of protein kinase activity;GO:0046850//regulation of bone remodeling;GO:0050796//regulation of insulin secretion;GO:0051971//positive regulation of transmission of nerve impulse;GO:0070093//negative regulation of glucagon secretion;GO:0070253//somatostatin secretion	--
ENSG00000164327	4.978	3.448	4.065	2.084	2.754	3.385	969	674	475	300	455	485	RICTOR	RPTOR independent companion of MTOR complex 2 [Source:HGNC Symbol;Acc:HGNC:28611]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K08267	GO:0005829//cytosol;GO:0031932//TORC2 complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043022//ribosome binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0001932//regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0009792//embryo development ending in birth or egg hatching;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0030838//positive regulation of actin filament polymerization;GO:0031532//actin cytoskeleton reorganization;GO:0031669//cellular response to nutrient levels;GO:0031929//TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0032956//regulation of actin cytoskeleton organization;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0038203//TORC2 signaling;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0050727//regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051896//regulation of protein kinase B signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000164329	9.165	7.517	9.466	7.68	8.415	8.981	571	480	437	353	422	399	TENT2	terminal nucleotidyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:26776]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031380//nuclear RNA-directed RNA polymerase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0034062//5'-3' RNA polymerase activity;GO:0046872//metal ion binding;GO:0070566//adenylyltransferase activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0021766//hippocampus development;GO:0030182//neuron differentiation;GO:0031123//RNA 3'-end processing;GO:0043489//RNA stabilization;GO:0043631//RNA polyadenylation;GO:0060041//retina development in camera-type eye;GO:0071044//histone mRNA catabolic process;GO:1990603//dark adaptation;GO:2000626//negative regulation of miRNA catabolic process	--
ENSG00000164330	0.021	0	0.029	0.015	0.013	0	1	0	1	1	1	0	EBF1	EBF transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3126]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070742//C2H2 zinc finger domain binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	COE
ENSG00000164331	7.675	7.391	9.626	7.048	8.741	7.757	344	333	303	234	331	253	ANKRA2	ankyrin repeat family A member 2 [Source:HGNC Symbol;Acc:HGNC:13208]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:1990393//3M complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0050750//low-density lipoprotein particle receptor binding	GO:0010468//regulation of gene expression;GO:0043254//regulation of protein-containing complex assembly	--
ENSG00000164332	8.231	7.682	7.31	5.944	6.652	6.842	372	349	244	199	254	225	UBLCP1	ubiquitin like domain containing CTD phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28110]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000164334	0	0	0	0	0	0	0	0	0	0	0	0	FAM170A	family with sequence similarity 170 member A [Source:HGNC Symbol;Acc:HGNC:27963]	-	-	-	-	GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0046872//metal ion binding	"GO:0006366//transcription by RNA polymerase II;GO:0009566//fertilization;GO:0045893//positive regulation of transcription, DNA-templated"	Others
ENSG00000164338	4.567	4.703	3.573	2.029	3.114	3.34	275	231	161	105	161	145	UTP15	UTP15 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:25758]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14549	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:2000234//positive regulation of rRNA processing	--
ENSG00000164342	1.816	1.687	2.156	2.319	2.159	1.589	83	86	67	73	74	63	TLR3	toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Immune system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04620//Toll-like receptor signaling pathway	K05401;K05401;K05401;K05401;K05401;K05401;K05401;K05401;K05401	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0036020//endolysosome membrane	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0000165//MAPK cascade;GO:0001774//microglial cell activation;GO:0001819//positive regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002730//regulation of dendritic cell cytokine production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006972//hyperosmotic response;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007252//I-kappaB phosphorylation;GO:0007254//JNK cascade;GO:0008584//male gonad development;GO:0009597//detection of virus;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0032481//positive regulation of type I interferon production;GO:0032722//positive regulation of chemokine production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034346//positive regulation of type III interferon production;GO:0035458//cellular response to interferon-beta;GO:0042742//defense response to bacterium;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0043331//response to dsRNA;GO:0045087//innate immune response;GO:0045671//negative regulation of osteoclast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0050729//positive regulation of inflammatory response;GO:0050896//response to stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0071260//cellular response to mechanical stimulus;GO:0071346//cellular response to interferon-gamma;GO:0071360//cellular response to exogenous dsRNA;GO:0071466//cellular response to xenobiotic stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097527//necroptotic signaling pathway;GO:0098586//cellular response to virus;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000164344	0.215	0.34	0.781	0.407	0.48	0.763	9	16	27	14	19	26	KLKB1	kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K01324	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	"GO:0004252//serine-type endopeptidase activity;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016787//hydrolase activity;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0002542//Factor XII activation;GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0031638//zymogen activation;GO:0031639//plasminogen activation;GO:0042730//fibrinolysis;GO:0051919//positive regulation of fibrinolysis	--
ENSG00000164346	32.454	31.31	32.208	29.961	26.167	28.257	1509.47	1453.45	995.48	988.87	1024.66	973.51	NSA2	NSA2 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:30728]	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding	GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000164347	15.668	14.012	14.139	12.007	11.563	11.28	823	747	559	470.96	518	457	GFM2	GTP dependent ribosome recycling factor mitochondrial 2 [Source:HGNC Symbol;Acc:HGNC:29682]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0032543//mitochondrial translation;GO:0032790//ribosome disassembly;GO:0070126//mitochondrial translational termination	--
ENSG00000164362	0	0	0	0	0	0	0	0	0	0	0	0	TERT	telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05225//Hepatocellular carcinoma;ko05226//Gastric cancer	K11126;K11126;K11126;K11126;K11126	"GO:0000333//telomerase catalytic core complex;GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0031379//RNA-directed RNA polymerase complex;GO:0042645//mitochondrial nucleoid;GO:1990572//TERT-RMRP complex"	GO:0000049//tRNA binding;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003720//telomerase activity;GO:0003721//telomerase RNA reverse transcriptase activity;GO:0003723//RNA binding;GO:0003964//RNA-directed DNA polymerase activity;GO:0003968//RNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042162//telomeric DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0070034//telomerase RNA binding;GO:0098680//template-free RNA nucleotidyltransferase	"GO:0000723//telomere maintenance;GO:0001172//transcription, RNA-templated;GO:0006278//RNA-dependent DNA biosynthetic process;GO:0007004//telomere maintenance via telomerase;GO:0007005//mitochondrion organization;GO:0010629//negative regulation of gene expression;GO:0022616//DNA strand elongation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030422//production of siRNA involved in RNA interference;GO:0031647//regulation of protein stability;GO:0032092//positive regulation of protein binding;GO:0042635//positive regulation of hair cycle;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0046326//positive regulation of glucose import;GO:0046686//response to cadmium ion;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0062103//double-stranded RNA biosynthetic process;GO:0070200//establishment of protein localization to telomere;GO:0071456//cellular response to hypoxia;GO:0071897//DNA biosynthetic process;GO:0090399//replicative senescence;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903620//positive regulation of transdifferentiation;GO:1903704//negative regulation of production of siRNA involved in RNA interference;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904751//positive regulation of protein localization to nucleolus;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000648//positive regulation of stem cell proliferation;GO:2000773//negative regulation of cellular senescence;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000164363	0	0	0	0	0	0	0	0	0	0	0	0	SLC6A18	solute carrier family 6 member 18 [Source:HGNC Symbol;Acc:HGNC:26441]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0035725//sodium ion transmembrane transport	--
ENSG00000164366	5.96	5.102	5.267	4.885	5.2	5.032	1009	917	749	663	737	705	CCDC127	coiled-coil domain containing 127 [Source:HGNC Symbol;Acc:HGNC:30520]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164379	0.163	0.198	0	0.073	0.086	0.149	9	11	0	3	4	6	FOXQ1	forkhead box Q1 [Source:HGNC Symbol;Acc:HGNC:20951]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0043524//negative regulation of neuron apoptotic process"	Fork_head
ENSG00000164398	0.891	1.046	1.466	1.402	1.863	1.026	74	65	71	72	88.04	63	ACSL6	acyl-CoA synthetase long chain family member 6 [Source:HGNC Symbol;Acc:HGNC:16496]	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0047676//arachidonate-CoA ligase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0008610//lipid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process	--
ENSG00000164399	0	0	0	0	0	0	0	0	0	0	0	0	IL3	interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Immune system;Immune disease;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04210//Apoptosis;ko04664//Fc epsilon RI signaling pathway;ko05310//Asthma;ko05221//Acute myeloid leukemia	K04736;K04736;K04736;K04736;K04736;K04736;K04736;K04736;K04736;K04736	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005135//interleukin-3 receptor binding;GO:0008083//growth factor activity	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0035162//embryonic hemopoiesis;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation	--
ENSG00000164400	0.122	0	0	0	0	0	2	0	0	0	0	0	CSF2	colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Signaling molecules and interaction;Cancer: overview;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: parasitic;Immune system;Signal transduction;Immune disease;Immune system;Signal transduction;Immune system;Immune system;Cancer: specific types	ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko05166//Human T-cell leukemia virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko05323//Rheumatoid arthritis;ko04664//Fc epsilon RI signaling pathway;ko04668//TNF signaling pathway;ko04660//T cell receptor signaling pathway;ko04657//IL-17 signaling pathway;ko05221//Acute myeloid leukemia	K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427;K05427	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0030526//granulocyte macrophage colony-stimulating factor receptor complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005125//cytokine activity;GO:0005129//granulocyte macrophage colony-stimulating factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0001821//histamine secretion;GO:0001892//embryonic placenta development;GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0030099//myeloid cell differentiation;GO:0030223//neutrophil differentiation;GO:0030224//monocyte differentiation;GO:0030225//macrophage differentiation;GO:0032747//positive regulation of interleukin-23 production;GO:0034021//response to silicon dioxide;GO:0034405//response to fluid shear stress;GO:0038157//granulocyte-macrophage colony-stimulating factor signaling pathway;GO:0042045//epithelial fluid transport;GO:0042116//macrophage activation;GO:0042127//regulation of cell population proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043011//myeloid dendritic cell differentiation;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070665//positive regulation of leukocyte proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0071803//positive regulation of podosome assembly;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0097028//dendritic cell differentiation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000164402	44.745	47.926	48.996	45.431	46.938	39.342	3634	3953	2845	2670	3216	2400.6	SEPTIN8	septin 8 [Source:HGNC Symbol;Acc:HGNC:16511]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16939;K16939	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031105//septin complex;GO:0031410//cytoplasmic vesicle;GO:0032153//cell division site;GO:0042995//cell projection;GO:0045202//synapse;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0060090//molecular adaptor activity	GO:0031647//regulation of protein stability;GO:0033157//regulation of intracellular protein transport;GO:0034613//cellular protein localization;GO:0035542//regulation of SNARE complex assembly;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000164403	1.964	2.37	2.502	2.423	2.802	3.06	120	154.15	127	122	158	144	SHROOM1	shroom family member 1 [Source:HGNC Symbol;Acc:HGNC:24084]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005912//adherens junction;GO:0016324//apical plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0043296//apical junction complex	GO:0003779//actin binding;GO:0045159//myosin II binding;GO:0051015//actin filament binding	GO:0000902//cell morphogenesis;GO:0007015//actin filament organization;GO:0051017//actin filament bundle assembly	--
ENSG00000164404	0.12	0.221	0.343	0.495	0.29	0.094	8	10	11	18	11	4	GDF9	growth differentiation factor 9 [Source:HGNC Symbol;Acc:HGNC:4224]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22673	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070698//type I activin receptor binding	GO:0001555//oocyte growth;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007292//female gamete generation;GO:0008284//positive regulation of cell population proliferation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction;GO:2000870//regulation of progesterone secretion	--
ENSG00000164405	26.65	29.984	34.018	33.893	27.284	33.125	437	446	373	425	371	379	UQCRQ	ubiquinol-cytochrome c reductase complex III subunit VII [Source:HGNC Symbol;Acc:HGNC:29594]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418;K00418	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	-	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0021539//subthalamus development;GO:0021548//pons development;GO:0021680//cerebellar Purkinje cell layer development;GO:0021766//hippocampus development;GO:0021794//thalamus development;GO:0021854//hypothalamus development;GO:0021860//pyramidal neuron development;GO:0030901//midbrain development;GO:0045333//cellular respiration"	--
ENSG00000164406	0	0	0.076	0	0.066	0.154	0	0	1	0	1	2	LEAP2	liver enriched antimicrobial peptide 2 [Source:HGNC Symbol;Acc:HGNC:29571]	-	-	-	-	GO:0005576//extracellular region	-	GO:0042742//defense response to bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000164411	0.169	0.063	0	0.114	0.025	0.029	2	3	0	1	1	1	GJB7	gap junction protein beta 7 [Source:HGNC Symbol;Acc:HGNC:16690]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0055085//transmembrane transport	--
ENSG00000164414	11.91	12.011	13.133	11.569	12.233	12.841	458	463.98	373	329	396	359	SLC35A1	solute carrier family 35 member A1 [Source:HGNC Symbol;Acc:HGNC:11021]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005456//CMP-N-acetylneuraminate transmembrane transporter activity;GO:0005459//UDP-galactose transmembrane transporter activity;GO:0005515//protein binding;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0015297//antiporter activity	GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0008643//carbohydrate transport;GO:0015782//CMP-N-acetylneuraminate transmembrane transport;GO:0072334//UDP-galactose transmembrane transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport	--
ENSG00000164418	0.119	0.318	0.087	0.191	0.157	0.074	12	28	5	11	9	4	GRIK2	glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04724//Glutamatergic synapse	K05202;K05202	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0005234//extracellularly glutamate-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity;GO:0038023//signaling receptor activity;GO:0099507//ligand-gated ion channel activity involved in regulation of presynaptic membrane potential;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001662//behavioral fear response;GO:0006811//ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0042391//regulation of membrane potential;GO:0043524//negative regulation of neuron apoptotic process;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission;GO:0050806//positive regulation of synaptic transmission;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060080//inhibitory postsynaptic potential;GO:0099505//regulation of presynaptic membrane potential;GO:0120169//detection of cold stimulus involved in thermoception"	--
ENSG00000164430	0.06	0.204	0.143	0.041	0.118	0.109	4	12	7	1	6	4	CGAS	cyclic GMP-AMP synthase [Source:HGNC Symbol;Acc:HGNC:21367]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko04623//Cytosolic DNA-sensing pathway	K17834;K17834;K17834;K17834;K17834;K17834	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035861//site of double-strand break	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0031491//nucleosome binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061501//2',3'-cyclic GMP-AMP synthase activity"	GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0002637//regulation of immunoglobulin production;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008340//determination of adult lifespan;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0019933//cAMP-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0032479//regulation of type I interferon production;GO:0032481//positive regulation of type I interferon production;GO:0038001//paracrine signaling;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045087//innate immune response;GO:0050776//regulation of immune response;GO:0050863//regulation of T cell activation;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2000774//positive regulation of cellular senescence	--
ENSG00000164434	0.614	0.367	0.249	0	0.109	0.422	10	6	3	0	2	5	FABP7	fatty acid binding protein 7 [Source:HGNC Symbol;Acc:HGNC:3562]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K08756	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0015908//fatty acid transport;GO:0050673//epithelial cell proliferation	--
ENSG00000164438	0	0	0	0	0	0	0	0	0	0	0	0	TLX3	T cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:HGNC:13532]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15607	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001708//cell fate specification;GO:0001764//neuron migration;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0030182//neuron differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0048513//animal organ development;GO:0048665//neuron fate specification"	Homeobox
ENSG00000164440	0	0.01	0	0	0.012	0.029	0	1	0	0	1	2	TXLNB	taxilin beta [Source:HGNC Symbol;Acc:HGNC:21617]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0019905//syntaxin binding	-	--
ENSG00000164442	22.834	23.8	22.745	28.729	29.149	26.732	913	920	621	787	946	771	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K21361	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0035035//histone acetyltransferase binding;GO:0046332//SMAD binding;GO:0050693//LBD domain binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001829//trophectodermal cell differentiation;GO:0001841//neural tube formation;GO:0001843//neural tube closure;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0002089//lens morphogenesis in camera-type eye;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002521//leukocyte differentiation;GO:0003151//outflow tract morphogenesis;GO:0003156//regulation of animal organ formation;GO:0003197//endocardial cushion development;GO:0003281//ventricular septum development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0007507//heart development;GO:0007530//sex determination;GO:0007569//cell aging;GO:0008283//cell population proliferation;GO:0008584//male gonad development;GO:0009612//response to mechanical stimulus;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0021602//cranial nerve morphogenesis;GO:0022409//positive regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030325//adrenal gland development;GO:0030336//negative regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030851//granulocyte differentiation;GO:0034405//response to fluid shear stress;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0035802//adrenal cortex formation;GO:0035914//skeletal muscle cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043627//response to estrogen;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046697//decidualization;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048821//erythrocyte development;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060136//embryonic process involved in female pregnancy;GO:0060349//bone morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0060971//embryonic heart tube left/right pattern formation;GO:0060972//left/right pattern formation;GO:0061156//pulmonary artery morphogenesis;GO:0061308//cardiac neural crest cell development involved in heart development;GO:0061371//determination of heart left/right asymmetry;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070986//left/right axis specification;GO:0071363//cellular response to growth factor stimulus;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:2000020//positive regulation of male gonad development"	--
ENSG00000164451	0.259	0.225	0.017	0.099	0.051	0.163	6	6	1	2	1	2	CALHM4	calcium homeostasis modulator family member 4 [Source:HGNC Symbol;Acc:HGNC:21094]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005261//cation channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000164458	0	0	0	0	0	0	0	0	0	0	0	0	TBXT	T-box transcription factor T [Source:HGNC Symbol;Acc:HGNC:11515]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001570//vasculogenesis;GO:0001707//mesoderm formation;GO:0001708//cell fate specification;GO:0001756//somitogenesis;GO:0001839//neural plate morphogenesis;GO:0001843//neural tube closure;GO:0003007//heart morphogenesis;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007341//penetration of zona pellucida;GO:0007498//mesoderm development;GO:0007509//mesoderm migration involved in gastrulation;GO:0008284//positive regulation of cell population proliferation;GO:0008595//anterior/posterior axis specification, embryo;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0014028//notochord formation;GO:0022414//reproductive process;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030903//notochord development;GO:0036342//post-anal tail morphogenesis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048706//embryonic skeletal system development;GO:0060349//bone morphogenesis;GO:0060395//SMAD protein signal transduction;GO:0061371//determination of heart left/right asymmetry;GO:0071300//cellular response to retinoic acid;GO:0090009//primitive streak formation"	T-box
ENSG00000164463	10.052	5.993	7.048	4.178	5.476	4.442	1004	627	493	356	409	412	CREBRF	CREB3 regulatory factor [Source:HGNC Symbol;Acc:HGNC:24050]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006986//response to unfolded protein;GO:0032388//positive regulation of intracellular transport;GO:0034976//response to endoplasmic reticulum stress;GO:0045732//positive regulation of protein catabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051222//positive regulation of protein transport;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response"	Others
ENSG00000164465	5.502	5.446	4.649	3.769	3.787	3.453	395	399	244	207	233	182	DCBLD1	"discoidin, CUB and LCCL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21479]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164466	15.61	17.509	16.892	19.937	14.72	20.087	1018	1010	750	706	745	742	SFXN1	sideroflexin 1 [Source:HGNC Symbol;Acc:HGNC:16085]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0022889//serine transmembrane transporter activity;GO:0042945//D-serine transmembrane transporter activity	GO:0006730//one-carbon metabolic process;GO:0006811//ion transport;GO:0006826//iron ion transport;GO:0006865//amino acid transport;GO:0015825//L-serine transport;GO:0030218//erythrocyte differentiation;GO:0034220//ion transmembrane transport;GO:0042942//D-serine transport;GO:0055085//transmembrane transport;GO:0140300//serine import into mitochondrion;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000164483	0	0.026	0	0.277	0	0.071	0	1	0	8	0	2	SAMD3	sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21574]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164484	3.419	3.161	2.897	2.765	3.094	2.786	216	203	136	136	171	127	TMEM200A	transmembrane protein 200A [Source:HGNC Symbol;Acc:HGNC:21075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000164485	0	0	0	0	0	0	0	0	0	0	0	0	IL22RA2	interleukin 22 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:14901]	Environmental Information Processing	Signal transduction	ko04630//JAK-STAT signaling pathway	K05139	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0042017//interleukin-22 binding;GO:0042018//interleukin-22 receptor activity	GO:0019221//cytokine-mediated signaling pathway;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0050728//negative regulation of inflammatory response	--
ENSG00000164488	0.094	0.16	0.224	0.261	0.235	0.354	4	10	8	12	12	16	DACT2	dishevelled binding antagonist of beta catenin 2 [Source:HGNC Symbol;Acc:HGNC:21231]	-	-	-	-	GO:0005737//cytoplasm	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008134//transcription factor binding;GO:0051018//protein kinase A binding;GO:0070097//delta-catenin binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0003382//epithelial cell morphogenesis;GO:0007162//negative regulation of cell adhesion;GO:0043588//skin development;GO:0072061//inner medullary collecting duct development;GO:1900108//negative regulation of nodal signaling pathway	--
ENSG00000164494	7.243	5.72	6.688	5.813	7	5.981	410	355	280	258	316	296	PDSS2	decaprenyl diphosphate synthase subunit 2 [Source:HGNC Symbol;Acc:HGNC:23041]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K12505	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1990234//transferase complex	GO:0000010//trans-hexaprenyltranstransferase activity;GO:0004659//prenyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046982//protein heterodimerization activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0097269//all-trans-decaprenyl-diphosphate synthase activity	GO:0006629//lipid metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0008299//isoprenoid biosynthetic process;GO:0021549//cerebellum development;GO:0050878//regulation of body fluid levels	--
ENSG00000164500	0	0	0	0	0	0	0	0	0	0	0	0	SPATA48	spermatogenesis associated 48 [Source:HGNC Symbol;Acc:HGNC:22564]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0007283//spermatogenesis;GO:0008150//biological_process	--
ENSG00000164506	2.75	3.641	1.653	1.899	3.169	2.525	323	287	139	144	208	199	STXBP5	syntaxin binding protein 5 [Source:HGNC Symbol;Acc:HGNC:19665]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0098674//extrinsic component of neuronal dense core vesicle membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098793//presynapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0045159//myosin II binding	GO:0006887//exocytosis;GO:0010807//regulation of synaptic vesicle priming;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0045921//positive regulation of exocytosis;GO:0050708//regulation of protein secretion;GO:0050790//regulation of catalytic activity;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000164508	0	0	0	0	0	0	0	0	0	0	0	0	H2AC1	H2A clustered histone 1 [Source:HGNC Symbol;Acc:HGNC:18729]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	"GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006325//chromatin organization	--
ENSG00000164509	0.043	0.017	0.049	0.087	0.062	0.19	4	3	4	11	9	5	IL31RA	interleukin 31 receptor A [Source:HGNC Symbol;Acc:HGNC:18969]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22630	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse	GO:0003713//transcription coactivator activity;GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019955//cytokine binding;GO:0051916//granulocyte colony-stimulating factor binding	"GO:0000165//MAPK cascade;GO:0002067//glandular epithelial cell differentiation;GO:0002376//immune system process;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0006952//defense response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0030224//monocyte differentiation;GO:0030225//macrophage differentiation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042592//homeostatic process;GO:0043031//negative regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0098542//defense response to other organism"	--
ENSG00000164512	0	0	0.026	0	0	0	0	0	1	0	0	0	ANKRD55	ankyrin repeat domain 55 [Source:HGNC Symbol;Acc:HGNC:25681]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164520	0.015	0.135	0.264	0.189	0.2	0.184	2	3	3	5	5	4	RAET1E	retinoic acid early transcript 1E [Source:HGNC Symbol;Acc:HGNC:16793]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07987	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0002376//immune system process;GO:0042267//natural killer cell mediated cytotoxicity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000164530	0	0	0.069	0	0.091	0	0	0	2	0	3	0	PI16	peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGNC:21245]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development	--
ENSG00000164532	0.291	0.579	0.322	0.428	0.501	0.182	11	22	9	12	16	5	TBX20	T-box transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11598]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001706//endoderm formation;GO:0001708//cell fate specification;GO:0001764//neuron migration;GO:0001947//heart looping;GO:0003143//embryonic heart tube morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003171//atrioventricular valve development;GO:0003175//tricuspid valve development;GO:0003176//aortic valve development;GO:0003180//aortic valve morphogenesis;GO:0003193//pulmonary valve formation;GO:0003203//endocardial cushion morphogenesis;GO:0003207//cardiac chamber formation;GO:0003215//cardiac right ventricle morphogenesis;GO:0003272//endocardial cushion formation;GO:0003279//cardiac septum development;GO:0003344//pericardium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006936//muscle contraction;GO:0008015//blood circulation;GO:0008283//cell population proliferation;GO:0009953//dorsal/ventral pattern formation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0014031//mesenchymal cell development;GO:0021524//visceral motor neuron differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0035050//embryonic heart tube development;GO:0035922//foramen ovale closure;GO:0036302//atrioventricular canal development;GO:0036306//embryonic heart tube elongation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048370//lateral mesoderm formation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060413//atrial septum morphogenesis;GO:0060577//pulmonary vein morphogenesis"	T-box
ENSG00000164535	7.456	8.857	8.861	8.723	9.803	9.961	437	493.08	368.01	371	434.02	384	DAGLB	diacylglycerol lipase beta [Source:HGNC Symbol;Acc:HGNC:28923]	Organismal Systems;Organismal Systems	Nervous system;Endocrine system	ko04723//Retrograde endocannabinoid signaling;ko04925//Aldosterone synthesis and secretion	K13806;K13806	GO:0005654//nucleoplasm;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane	GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047372//acylglycerol lipase activity	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0006690//icosanoid metabolic process;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007405//neuroblast proliferation;GO:0010898//positive regulation of triglyceride catabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0022008//neurogenesis;GO:0042136//neurotransmitter biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0071926//endocannabinoid signaling pathway;GO:0098921//retrograde trans-synaptic signaling by endocannabinoid	--
ENSG00000164542	11.53	8.169	7.923	9.666	8.006	9.697	726	612	453	398	452	406	KIAA0895	KIAA0895 [Source:HGNC Symbol;Acc:HGNC:22206]	-	-	-	-	-	-	-	--
ENSG00000164543	6.112	4.855	4.09	3.922	4.043	5.214	326	256	163	150	186	207	STK17A	serine/threonine kinase 17a [Source:HGNC Symbol;Acc:HGNC:11395]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000164548	17.061	15.927	14.519	12.076	15.113	16.748	639	601	405	339	460	461	TRA2A	transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645]	Human Diseases;Genetic Information Processing	Endocrine and metabolic disease;Transcription	ko04936//Alcoholic liver disease;ko03040//Spliceosome	K12897;K12897	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000164574	77.108	83.36	83.456	74.94	76.382	64.271	9461	10312	7591	6831	7926	5759	GALNT10	polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19873]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing	--
ENSG00000164576	8.949	8.422	8.654	7.85	7.75	9.77	1148	1086	820	746	840	912	SAP30L	SAP30 like [Source:HGNC Symbol;Acc:HGNC:25663]	Human Diseases	Infectious disease: viral	ko05169//Epstein-Barr virus infection	K19202	GO:0000118//histone deacetylase complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016580//Sin3 complex	"GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0031491//nucleosome binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0042393//histone binding;GO:0044378//non-sequence-specific DNA binding, bending;GO:0046872//metal ion binding;GO:0070273//phosphatidylinositol-4-phosphate binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance"	--
ENSG00000164587	451.696	478.144	443.836	584.075	439.058	415.672	8096	8520	5901	7465	6528	5434	RPS14	ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:10387]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02955;K02955	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045182//translation regulator activity;GO:0048027//mRNA 5'-UTR binding;GO:0070181//small ribosomal subunit rRNA binding	"GO:0000028//ribosomal small subunit assembly;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006417//regulation of translation;GO:0030218//erythrocyte differentiation;GO:0030490//maturation of SSU-rRNA"	--
ENSG00000164588	0.228	0.13	0.079	0.321	0.385	0.34	47	27	12	49	67	51	HCN1	hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845]	Organismal Systems	Endocrine system	ko04929//GnRH secretion	K04954	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0098855//HCN channel complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0022843//voltage-gated cation channel activity;GO:0030552//cAMP binding;GO:0042802//identical protein binding	"GO:0003254//regulation of membrane depolarization;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0045176//apical protein localization;GO:0046549//retinal cone cell development;GO:0051289//protein homotetramerization;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0055085//transmembrane transport;GO:0071320//cellular response to cAMP;GO:0071805//potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098907//regulation of SA node cell action potential;GO:2001257//regulation of cation channel activity"	--
ENSG00000164591	0.366	0.322	0.133	0.542	0.4	1.317	26	23	7	20	24	23	MYOZ3	myozenin 3 [Source:HGNC Symbol;Acc:HGNC:18565]	-	-	-	-	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030018//Z disc	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031433//telethonin binding;GO:0051373//FATZ binding	-	--
ENSG00000164597	12.067	12.5	13.576	11.158	11.672	8.239	787.44	621.46	463.24	416.55	506.86	460.59	COG5	component of oligomeric golgi complex 5 [Source:HGNC Symbol;Acc:HGNC:14857]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0048219//inter-Golgi cisterna vesicle-mediated transport;GO:0070085//glycosylation"	--
ENSG00000164600	0	0	0	0	0	0	0	0	0	0	0	0	NEUROD6	neuronal differentiation 6 [Source:HGNC Symbol;Acc:HGNC:13804]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0021542//dentate gyrus development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000164603	9.31	6.878	6.594	7.068	6.866	6.645	700	565	398	396	424	393	BMT2	base methyltransferase of 25S rRNA 2 homolog [Source:HGNC Symbol;Acc:HGNC:26475]	-	-	-	-	GO:0005829//cytosol;GO:0140007//KICSTOR complex;GO:1990130//GATOR1 complex	GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0032259//methylation;GO:0034198//cellular response to amino acid starvation;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000164604	2.405	3.521	2.698	1.025	1.648	1.895	169	199	91	50	92	91	GPR85	G protein-coupled receptor 85 [Source:HGNC Symbol;Acc:HGNC:4536]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000164609	9.852	7.376	7.098	8.888	7.282	8.003	639	507	348	338	406	396	SLU7	"SLU7 homolog, splicing factor [Source:HGNC Symbol;Acc:HGNC:16939]"	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12819	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030532//small nuclear ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0071013//catalytic step 2 spliceosome	GO:0000386//second spliceosomal transesterification activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0046872//metal ion binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006886//intracellular protein transport;GO:0008380//RNA splicing;GO:0034605//cellular response to heat"	--
ENSG00000164610	4.715	4.733	4.774	4.092	4.861	4.963	111	112	83	72	97	86	RP9	RP9 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:10288]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K19604	GO:0005634//nucleus;GO:0005785//signal recognition particle receptor complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008380//RNA splicing;GO:0050890//cognition	--
ENSG00000164611	3.822	2.87	4.716	4.983	2.896	2.78	57	45	52	56	38	30	PTTG1	"PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690]"	Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Cell growth and death;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04114//Oocyte meiosis;ko04110//Cell cycle	K06635;K06635;K06635	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007283//spermatogenesis;GO:0010951//negative regulation of endopeptidase activity;GO:0045143//homologous chromosome segregation;GO:0051276//chromosome organization;GO:0051301//cell division;GO:2000816//negative regulation of mitotic sister chromatid separation	--
ENSG00000164615	29.38	29.127	27.147	29.324	27.156	26.79	991	995	705	755	798	685	CAMLG	calcium modulating ligand [Source:HGNC Symbol;Acc:HGNC:1471]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043529//GET complex	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0001782//B cell homeostasis;GO:0001881//receptor recycling;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0031397//negative regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045048//protein insertion into ER membrane;GO:0050821//protein stabilization;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000164619	0	0.145	0.067	0.024	0.064	0.095	0	7	3	1	3	4	BMPER	BMP binding endothelial regulator [Source:HGNC Symbol;Acc:HGNC:24154]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0001568//blood vessel development;GO:0001657//ureteric bud development;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007182//common-partner SMAD protein phosphorylation;GO:0010594//regulation of endothelial cell migration;GO:0030509//BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0032880//regulation of protein localization;GO:0042118//endothelial cell activation;GO:0045765//regulation of angiogenesis;GO:0048839//inner ear development;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000164620	1.74	1.628	1.634	1.688	1.448	3.255	72.87	75.83	56.53	57.81	56.5	103.31	RELL2	RELT like 2 [Source:HGNC Symbol;Acc:HGNC:26902]	-	-	-	-	GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0005518//collagen binding	GO:0010811//positive regulation of cell-substrate adhesion;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000164626	4.766	4.666	6.678	6.228	6.019	11.122	374	368	387	362	399	635	KCNK5	potassium two pore domain channel subfamily K member 5 [Source:HGNC Symbol;Acc:HGNC:6280]	Organismal Systems;Organismal Systems	Digestive system;Sensory system	ko04974//Protein digestion and absorption;ko04742//Taste transduction	K04916;K04916	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0060075//regulation of resting membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0097623//potassium ion export across plasma membrane;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000164627	3.902	3.428	1.827	2.025	2.915	2.928	160	137	56	62	94	88	KIF6	kinesin family member 6 [Source:HGNC Symbol;Acc:HGNC:21202]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement	--
ENSG00000164631	6.422	5.969	5.222	4.349	5.013	5.327	676	579	406	333	445	408	ZNF12	zinc finger protein 12 [Source:HGNC Symbol;Acc:HGNC:12902]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000164638	53.228	59.875	44.333	40.961	49.062	29.517	3279	3593	1951	1815	2421	1222	SLC29A4	solute carrier family 29 member 4 [Source:HGNC Symbol;Acc:HGNC:23097]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0098793//presynapse	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005337//nucleoside transmembrane transporter activity;GO:0005342//organic acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008504//monoamine transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0001692//histamine metabolic process;GO:0006836//neurotransmitter transport;GO:0015695//organic cation transport;GO:0015844//monoamine transport;GO:0042908//xenobiotic transport;GO:0051610//serotonin uptake;GO:0051615//histamine uptake;GO:0051620//norepinephrine uptake;GO:0051625//epinephrine uptake;GO:0055085//transmembrane transport;GO:0090494//dopamine uptake;GO:0098655//cation transmembrane transport;GO:0140115//export across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1901642//nucleoside transmembrane transport;GO:1901998//toxin transport;GO:1903825//organic acid transmembrane transport	--
ENSG00000164645	0	0	0	0	0	0	0	0	0	0	0	0	TEX47	testis expressed 47 [Source:HGNC Symbol;Acc:HGNC:22402]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164647	0.395	0.63	0.803	0.801	0.702	0.924	10	16	15	15	15	17	STEAP1	STEAP family member 1 [Source:HGNC Symbol;Acc:HGNC:11378]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14737	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005215//transporter activity;GO:0015267//channel activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0055072//iron ion homeostasis;GO:0055085//transmembrane transport	--
ENSG00000164649	18.099	18.73	16.696	14.572	12.45	11.676	872.35	916.75	567.81	506.89	506.7	424.94	CDCA7L	cell division cycle associated 7 like [Source:HGNC Symbol;Acc:HGNC:30777]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0051301//cell division"	--
ENSG00000164651	0.027	0	0	0.042	0.033	0.018	2	0	0	2	1	1	SP8	Sp8 transcription factor [Source:HGNC Symbol;Acc:HGNC:19196]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0030326//embryonic limb morphogenesis	zf-C2H2
ENSG00000164654	10.572	9.12	8.526	7.95	7.839	7.452	696	515	378	305	334	304	MIOS	meiosis regulator for oocyte development [Source:HGNC Symbol;Acc:HGNC:21905]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20407	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0061700//GATOR2 complex	GO:0005515//protein binding	GO:0031503//protein-containing complex localization;GO:0032008//positive regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:1904262//negative regulation of TORC1 signaling;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000164659	4.783	3.769	3.926	3.604	3.786	4.559	414	326	265	217	281	266	ELAPOR2	endosome-lysosome associated apoptosis and autophagy regulator family member 2 [Source:HGNC Symbol;Acc:HGNC:21945]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0070700//BMP receptor binding	GO:0030513//positive regulation of BMP signaling pathway;GO:0045684//positive regulation of epidermis development;GO:0051961//negative regulation of nervous system development	--
ENSG00000164663	1.323	1.132	0.853	0.594	0.69	1.419	150.43	163.79	110	64	96.35	109.68	USP49	ubiquitin specific peptidase 49 [Source:HGNC Symbol;Acc:HGNC:20078]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006325//chromatin organization;GO:0006397//mRNA processing;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008380//RNA splicing;GO:0016579//protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination"	--
ENSG00000164674	4.504	3.88	4.078	2.672	3.256	3.398	239	205	161	106	147	131	SYTL3	synaptotagmin like 3 [Source:HGNC Symbol;Acc:HGNC:15587]	-	-	-	-	GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0070382//exocytic vesicle	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0031267//small GTPase binding;GO:0042043//neurexin family protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis	--
ENSG00000164675	0.906	0.601	0.688	0.366	0.47	0.381	57	38	32	17	25	16	IQUB	IQ motif and ubiquitin domain containing [Source:HGNC Symbol;Acc:HGNC:21995]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0031514//motile cilium	GO:0005515//protein binding	GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000164683	0.237	0.272	0.518	0.34	0.408	0.24	10	13	17	7	9	6	HEY1	hes related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05224//Breast cancer;ko04330//Notch signaling pathway	K09091;K09091;K09091;K09091	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0003161//cardiac conduction system development;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003190//atrioventricular valve formation;GO:0003203//endocardial cushion morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0035912//dorsal aorta morphogenesis;GO:0036304//umbilical cord morphogenesis;GO:0045665//negative regulation of neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0060347//heart trabecula formation;GO:0060411//cardiac septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0060716//labyrinthine layer blood vessel development;GO:0060842//arterial endothelial cell differentiation;GO:0061314//Notch signaling involved in heart development;GO:0070168//negative regulation of biomineral tissue development;GO:0072359//circulatory system development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:2001212//regulation of vasculogenesis"	bHLH
ENSG00000164684	3.3	3.54	2.793	1.383	1.916	0.871	687	560	334	213	284	189	ZNF704	zinc finger protein 704 [Source:HGNC Symbol;Acc:HGNC:32291]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	Others
ENSG00000164687	7.845	8.94	4.539	11.939	7.682	9.606	110	126	47	124	91	98	FABP5	fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K08754	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030667//secretory granule membrane;GO:0035578//azurophil granule lumen;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0001972//retinoic acid binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding	GO:0006006//glucose metabolic process;GO:0006629//lipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006869//lipid transport;GO:0008544//epidermis development;GO:0010829//negative regulation of glucose transmembrane transport;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0031392//regulation of prostaglandin biosynthetic process;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0051930//regulation of sensory perception of pain;GO:0099178//regulation of retrograde trans-synaptic signaling by endocanabinoid;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1990379//lipid transport across blood-brain barrier	--
ENSG00000164690	0	0	0	0	0.012	0	0	0	0	0	1	0	SHH	sonic hedgehog signaling molecule [Source:HGNC Symbol;Acc:HGNC:10848]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: overview;Development and regeneration;Cancer: specific types;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko05226//Gastric cancer;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K11988;K11988;K11988;K11988;K11988;K11988	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0005113//patched binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008233//peptidase activity;GO:0008270//zinc ion binding;GO:0016015//morphogen activity;GO:0016787//hydrolase activity;GO:0043237//laminin-1 binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001656//metanephros development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001708//cell fate specification;GO:0001755//neural crest cell migration;GO:0001822//kidney development;GO:0001942//hair follicle development;GO:0001944//vasculature development;GO:0001947//heart looping;GO:0002052//positive regulation of neuroblast proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002076//osteoblast development;GO:0002320//lymphoid progenitor cell differentiation;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0007224//smoothened signaling pathway;GO:0007228//positive regulation of hh target transcription factor activity;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0007389//pattern specification process;GO:0007398//ectoderm development;GO:0007405//neuroblast proliferation;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007418//ventral midline development;GO:0007442//hindgut morphogenesis;GO:0007507//heart development;GO:0007596//blood coagulation;GO:0008209//androgen metabolic process;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0009949//polarity specification of anterior/posterior axis;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0010463//mesenchymal cell proliferation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014003//oligodendrocyte development;GO:0014706//striated muscle tissue development;GO:0014858//positive regulation of skeletal muscle cell proliferation;GO:0014902//myotube differentiation;GO:0016539//intein-mediated protein splicing;GO:0016540//protein autoprocessing;GO:0021513//spinal cord dorsal/ventral patterning;GO:0021522//spinal cord motor neuron differentiation;GO:0021794//thalamus development;GO:0021871//forebrain regionalization;GO:0021904//dorsal/ventral neural tube patterning;GO:0021924//cell proliferation in external granule layer;GO:0021930//cerebellar granule cell precursor proliferation;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0021978//telencephalon regionalization;GO:0030010//establishment of cell polarity;GO:0030162//regulation of proteolysis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030323//respiratory tube development;GO:0030324//lung development;GO:0030326//embryonic limb morphogenesis;GO:0030336//negative regulation of cell migration;GO:0030539//male genitalia development;GO:0030850//prostate gland development;GO:0030878//thyroid gland development;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0031016//pancreas development;GO:0031069//hair follicle morphogenesis;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033077//T cell differentiation in thymus;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0034504//protein localization to nucleus;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0042307//positive regulation of protein import into nucleus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042476//odontogenesis;GO:0042481//regulation of odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0043588//skin development;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0045109//intermediate filament organization;GO:0045165//cell fate commitment;GO:0045445//myoblast differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046639//negative regulation of alpha-beta T cell differentiation;GO:0048468//cell development;GO:0048538//thymus development;GO:0048546//digestive tract morphogenesis;GO:0048557//embryonic digestive tract morphogenesis;GO:0048568//embryonic organ development;GO:0048589//developmental growth;GO:0048598//embryonic morphogenesis;GO:0048617//embryonic foregut morphogenesis;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048645//animal organ formation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048663//neuron fate commitment;GO:0048706//embryonic skeletal system development;GO:0048709//oligodendrocyte differentiation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0048745//smooth muscle tissue development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048839//inner ear development;GO:0048856//anatomical structure development;GO:0048859//formation of anatomical boundary;GO:0048864//stem cell development;GO:0051146//striated muscle cell differentiation;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0051781//positive regulation of cell division;GO:0060020//Bergmann glial cell differentiation;GO:0060021//roof of mouth development;GO:0060070//canonical Wnt signaling pathway;GO:0060173//limb development;GO:0060174//limb bud formation;GO:0060425//lung morphogenesis;GO:0060428//lung epithelium development;GO:0060438//trachea development;GO:0060439//trachea morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060447//bud outgrowth involved in lung branching;GO:0060458//right lung development;GO:0060459//left lung development;GO:0060463//lung lobe morphogenesis;GO:0060484//lung-associated mesenchyme development;GO:0060516//primary prostatic bud elongation;GO:0060523//prostate epithelial cord elongation;GO:0060662//salivary gland cavitation;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060684//epithelial-mesenchymal cell signaling;GO:0060685//regulation of prostatic bud formation;GO:0060738//epithelial-mesenchymal signaling involved in prostate gland development;GO:0060768//regulation of epithelial cell proliferation involved in prostate gland development;GO:0060769//positive regulation of epithelial cell proliferation involved in prostate gland development;GO:0060782//regulation of mesenchymal cell proliferation involved in prostate gland development;GO:0060783//mesenchymal smoothened signaling pathway involved in prostate gland development;GO:0060840//artery development;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0061053//somite development;GO:0061189//positive regulation of sclerotome development;GO:0071285//cellular response to lithium ion;GO:0071542//dopaminergic neuron differentiation;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0072205//metanephric collecting duct development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090370//negative regulation of cholesterol efflux;GO:0097190//apoptotic signaling pathway;GO:1900175//regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:1900180//regulation of protein localization to nucleus;GO:1904339//negative regulation of dopaminergic neuron differentiation;GO:1905327//tracheoesophageal septum formation;GO:2000062//negative regulation of ureter smooth muscle cell differentiation;GO:2000063//positive regulation of ureter smooth muscle cell differentiation;GO:2000357//negative regulation of kidney smooth muscle cell differentiation;GO:2000358//positive regulation of kidney smooth muscle cell differentiation;GO:2000729//positive regulation of mesenchymal cell proliferation involved in ureter development;GO:2001054//negative regulation of mesenchymal cell apoptotic process"	--
ENSG00000164691	0	0	0	0	0	0	0	0	0	0	0	0	TAGAP	T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000164692	122.971	145.294	61.004	54.281	66.437	43.451	12937	15364	4740	4230	5905	3326	COL1A2	collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Immune system;Digestive system;Endocrine and metabolic disease;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04512//ECM-receptor interaction	K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005584//collagen type I trimer;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048407//platelet-derived growth factor binding	GO:0001501//skeletal system development;GO:0001568//blood vessel development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0008217//regulation of blood pressure;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030282//bone mineralization;GO:0032963//collagen metabolic process;GO:0042476//odontogenesis;GO:0043589//skin morphogenesis;GO:0070208//protein heterotrimerization;GO:0071230//cellular response to amino acid stimulus;GO:0085029//extracellular matrix assembly	--
ENSG00000164694	9.034	11.024	10.364	6.093	7.364	6.183	1227	1505	1038	613	845	611	FNDC1	fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21184]	-	-	-	-	GO:0005576//extracellular region;GO:0016607//nuclear speck	GO:0005515//protein binding	-	--
ENSG00000164695	3.514	2.952	3.137	3.233	3.02	3.113	135	114	89	92	98	87	CHMP4C	charged multivesicular body protein 4C [Source:HGNC Symbol;Acc:HGNC:30599]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K24782;K24782	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0090543//Flemming body;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0001778//plasma membrane repair;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0009838//abscission;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0031468//nuclear membrane reassembly;GO:0032466//negative regulation of cytokinesis;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0044878//mitotic cytokinesis checkpoint signaling;GO:0046761//viral budding from plasma membrane;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0090611//ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport	--
ENSG00000164707	6.612	8.74	5.06	4.393	5.189	3.376	398	529	225	196	264	148	SLC13A4	solute carrier family 13 member 4 [Source:HGNC Symbol;Acc:HGNC:15827]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015382//sodium:sulfate symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008272//sulfate transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000164708	5.1	4.83	3.384	3.473	3.952	2.858	88.54	84.28	43.39	44.66	57.96	36.1	PGAM2	phosphoglycerate mutase 2 [Source:HGNC Symbol;Acc:HGNC:8889]	Metabolism;Metabolism;Organismal Systems;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Endocrine system;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00260//Glycine, serine and threonine metabolism"	K01834;K01834;K01834;K01834;K01834;K01834;K01834	GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0042802//identical protein binding;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"	GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0006941//striated muscle contraction;GO:0007219//Notch signaling pathway;GO:0007283//spermatogenesis;GO:0010035//response to inorganic substance;GO:0046689//response to mercury ion	--
ENSG00000164713	59.592	56.063	65.849	73.246	57.719	62.7	973.02	919.26	791.78	883.96	797	742.47	BRI3	brain protein I3 [Source:HGNC Symbol;Acc:HGNC:1109]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000164715	6.178	6.644	6.736	5.679	6.397	7.421	1150	1243	926	783	1006	1005	LMTK2	lemur tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:17880]	-	-	-	-	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0070853//myosin VI binding;GO:0106310//protein serine kinase activity	GO:0001881//receptor recycling;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007409//axonogenesis;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032456//endocytic recycling;GO:0033572//transferrin transport;GO:0033674//positive regulation of kinase activity;GO:0043086//negative regulation of catalytic activity;GO:0045022//early endosome to late endosome transport;GO:0046777//protein autophosphorylation	--
ENSG00000164729	0	0	0	0	0	0	0	0	0	0	0	0	SLC35G3	solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000164733	411.857	433.489	424.763	410.901	413.623	401.555	18419	19451.38	14226	13840	15622	13122	CTSB	cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527]	Organismal Systems;Cellular Processes;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems	Immune system;Transport and catabolism;Cell growth and death;Transport and catabolism;Immune system;Endocrine system	ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04210//Apoptosis;ko04142//Lysosome;ko04612//Antigen processing and presentation;ko04924//Renin secretion	K01363;K01363;K01363;K01363;K01363;K01363	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0036021//endolysosome lumen;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904090//peptidase inhibitor complex;GO:1904813//ficolin-1-rich granule lumen	GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043394//proteoglycan binding	GO:0006508//proteolysis;GO:0006590//thyroid hormone generation;GO:0010466//negative regulation of peptidase activity;GO:0030574//collagen catabolic process;GO:0030855//epithelial cell differentiation;GO:0042981//regulation of apoptotic process;GO:0046697//decidualization;GO:0046718//viral entry into host cell;GO:0050790//regulation of catalytic activity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0097067//cellular response to thyroid hormone stimulus	--
ENSG00000164736	0	0	0	0	0	0	0	0	0	0	0	0	SOX17	SRY-box transcription factor 17 [Source:HGNC Symbol;Acc:HGNC:18122]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04495	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001656//metanephros development;GO:0001706//endoderm formation;GO:0001714//endodermal cell fate specification;GO:0001828//inner cell mass cellular morphogenesis;GO:0001947//heart looping;GO:0003142//cardiogenic plate morphogenesis;GO:0003143//embryonic heart tube morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0007493//endodermal cell fate determination;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0021903//rostrocaudal neural tube patterning;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0031648//protein destabilization;GO:0035050//embryonic heart tube development;GO:0042074//cell migration involved in gastrulation;GO:0045595//regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0048568//embryonic organ development;GO:0048617//embryonic foregut morphogenesis;GO:0048863//stem cell differentiation;GO:0048866//stem cell fate specification;GO:0050821//protein stabilization;GO:0060214//endocardium formation;GO:0060913//cardiac cell fate determination;GO:0060914//heart formation;GO:0060956//endocardial cell differentiation;GO:0061009//common bile duct development;GO:0061010//gall bladder development;GO:0061031//endodermal digestive tract morphogenesis;GO:0072091//regulation of stem cell proliferation;GO:0072189//ureter development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1990830//cellular response to leukemia inhibitory factor;GO:2000035//regulation of stem cell division;GO:2000043//regulation of cardiac cell fate specification"	HMG
ENSG00000164741	4.257	3.846	3.171	2.682	2.869	3.247	486	453	260	248	279	276	DLC1	DLC1 Rho GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:2897]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0032587//ruffle membrane;GO:0045121//membrane raft	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042169//SH2 domain binding	GO:0001843//neural tube closure;GO:0003007//heart morphogenesis;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0021575//hindbrain morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0030900//forebrain development;GO:0032956//regulation of actin cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035307//positive regulation of protein dephosphorylation;GO:0048041//focal adhesion assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:1900119//positive regulation of execution phase of apoptosis	--
ENSG00000164742	1.367	1.433	1.918	2.501	1.625	2.149	253	241	175	268	279	250	ADCY1	adenylate cyclase 1 [Source:HGNC Symbol;Acc:HGNC:232]	Metabolism;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Infectious disease: parasitic;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Infectious disease: parasitic;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Nervous system;Aging;Endocrine system;Endocrine system;Endocrine system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis"	K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041;K08041	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008294//calcium- and calmodulin-responsive adenylate cyclase activity;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding	GO:0002682//regulation of immune system process;GO:0006171//cAMP biosynthetic process;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007409//axonogenesis;GO:0007420//brain development;GO:0007616//long-term memory;GO:0007623//circadian rhythm;GO:0009190//cyclic nucleotide biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0010226//response to lithium ion;GO:0019933//cAMP-mediated signaling;GO:0032793//positive regulation of CREB transcription factor activity;GO:0035556//intracellular signal transduction;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0050804//modulation of chemical synaptic transmission;GO:0065008//regulation of biological quality;GO:0071277//cellular response to calcium ion;GO:0150076//neuroinflammatory response;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1904322//cellular response to forskolin;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000164743	2.614	2.364	1.333	1.742	1.085	1.4	77	70	29	38	27	30	C8orf48	chromosome 8 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:26345]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000164744	0	0	0	0	0	0	0	0	0	0	0	0	SUN3	Sad1 and UNC84 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22429]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex	GO:0043495//protein-membrane adaptor activity	GO:0006998//nuclear envelope organization	--
ENSG00000164746	0.125	0.174	0.195	0.124	0.03	0	5	7	6	4	1	0	C7orf57	chromosome 7 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:22247]	-	-	-	-	-	-	-	--
ENSG00000164749	0.459	0.363	0.299	0.127	0.755	0.324	31	31	15	8	37	20	HNF4G	hepatocyte nuclear factor 4 gamma [Source:HGNC Symbol;Acc:HGNC:5026]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08037	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	RXR-like
ENSG00000164751	31.715	27.263	27.532	25.395	22.631	22.755	896	890	618	566	619	562	PEX2	peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K06664	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016593//Cdc73/Paf1 complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000038//very long-chain fatty acid metabolic process;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006635//fatty acid beta-oxidation;GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix;GO:0031648//protein destabilization;GO:0048147//negative regulation of fibroblast proliferation;GO:0050680//negative regulation of epithelial cell proliferation	--
ENSG00000164754	45.018	36.196	36.567	27.976	31.308	34.61	3417	2762	2050	1573	2008	1911	RAD21	RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06670	"GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008278//cohesin complex;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030496//midbody;GO:0034990//nuclear mitotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex"	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0034089//establishment of meiotic sister chromatid cohesion;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0045876//positive regulation of sister chromatid cohesion;GO:0051301//cell division;GO:0071168//protein localization to chromatin;GO:1990414//replication-born double-strand break repair via sister chromatid exchange	--
ENSG00000164756	0.998	0.699	0.473	0.277	0.32	0.108	71	75	38	21	12	4	SLC30A8	solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008324//cation transmembrane transporter activity;GO:0042803//protein homodimerization activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0009749//response to glucose;GO:0010043//response to zinc ion;GO:0030070//insulin processing;GO:0030073//insulin secretion;GO:0032024//positive regulation of insulin secretion;GO:0032119//sequestering of zinc ion;GO:0034341//response to interferon-gamma;GO:0055085//transmembrane transport;GO:0060627//regulation of vesicle-mediated transport;GO:0061088//regulation of sequestering of zinc ion;GO:0070555//response to interleukin-1;GO:0071577//zinc ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000164758	4.307	3.214	3.247	3.7	2.781	4.843	88	66	49	56	48	72	MED30	mediator complex subunit 30 [Source:HGNC Symbol;Acc:HGNC:23032]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15143	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0016567//protein ubiquitination;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000164761	0.809	0.988	0.438	0.374	0.328	0.54	35	43	14	12	12	17	TNFRSF11B	TNF receptor superfamily member 11b [Source:HGNC Symbol;Acc:HGNC:11909]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Development and regeneration	ko04060//Cytokine-cytokine receptor interaction;ko04380//Osteoclast differentiation	K05148;K05148	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0043235//receptor complex	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001501//skeletal system development;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0010035//response to inorganic substance;GO:0030198//extracellular matrix organization;GO:0032026//response to magnesium ion;GO:0042489//negative regulation of odontogenesis of dentin-containing tooth;GO:0043627//response to estrogen;GO:0045671//negative regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:0046685//response to arsenic-containing substance	--
ENSG00000164764	9.96	8.405	6.796	14.573	13.549	12.596	764	648	385	828	878	703	SBSPON	somatomedin B and thrombospondin type 1 domain containing [Source:HGNC Symbol;Acc:HGNC:30362]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent	-	--
ENSG00000164776	0.405	0.516	0.72	0.16	0.105	0.033	17.43	13.25	11.22	5.11	4.11	1.02	PHKG1	phosphorylase kinase catalytic subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:8930]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04910//Insulin signaling pathway;ko04922//Glucagon signaling pathway	K00871;K00871;K00871	GO:0005829//cytosol;GO:0005964//phosphorylase kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004689//phosphorylase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0050321//tau-protein kinase activity;GO:0106310//protein serine kinase activity	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000164778	0.028	0.028	0.038	0.058	0.034	0.02	2	2	2	3	2	1	EN2	engrailed homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3343]	Environmental Information Processing	Signal transduction	ko04341//Hedgehog signaling pathway - fly	K09319	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0030182//neuron differentiation;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0043524//negative regulation of neuron apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048666//neuron development;GO:1990403//embryonic brain development"	Homeobox
ENSG00000164794	0.017	0.035	0.045	0.044	0.061	0.12	2	5	2	2	5	10	KCNV1	potassium voltage-gated channel modifier subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:18861]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045171//intercellular bridge	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0008200//ion channel inhibitor activity;GO:0015459//potassium channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000164796	0	0	0.006	0.01	0.005	0	0	0	1	2	1	0	CSMD3	CUB and Sushi multiple domains 3 [Source:HGNC Symbol;Acc:HGNC:19291]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0050773//regulation of dendrite development	--
ENSG00000164808	14.135	10.336	12.388	12.771	15.149	12.524	613	580	502	430	487	484	SPIDR	scaffold protein involved in DNA repair [Source:HGNC Symbol;Acc:HGNC:28971]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0031334//positive regulation of protein-containing complex assembly;GO:0070202//regulation of establishment of protein localization to chromosome;GO:0071479//cellular response to ionizing radiation;GO:0072711//cellular response to hydroxyurea;GO:0072757//cellular response to camptothecin;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000164815	6.319	5.897	6.412	6.35	4.766	7.606	249	234	189	187	158	220	ORC5	origin recognition complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:8491]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K02607	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003688//DNA replication origin binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0006275//regulation of DNA replication	--
ENSG00000164816	0	0	0	0	0	0	0	0	0	0	0	0	DEFA5	defensin alpha 5 [Source:HGNC Symbol;Acc:HGNC:2764]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0030133//transport vesicle;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006952//defense response;GO:0019731//antibacterial humoral response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051673//membrane disruption in other organism;GO:0051873//killing by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide;GO:1905710//positive regulation of membrane permeability	--
ENSG00000164818	12.497	12.79	14.268	11.571	11.927	11.966	825	839	678	594	653	563	DNAAF5	dynein axonemal assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:26013]	-	-	-	-	GO:0005737//cytoplasm;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding	GO:0003341//cilium movement;GO:0030030//cell projection organization;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly	--
ENSG00000164821	0	0	0	0	0	0	0	0	0	0	0	0	DEFA4	defensin alpha 4 [Source:HGNC Symbol;Acc:HGNC:2763]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0035580//specific granule lumen;GO:0042582//azurophil granule	GO:0042803//protein homodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006952//defense response;GO:0019730//antimicrobial humoral response;GO:0019731//antibacterial humoral response;GO:0019732//antifungal humoral response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051673//membrane disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000164822	0	0	0	0	0	0	0	0	0	0	0	0	DEFA6	defensin alpha 6 [Source:HGNC Symbol;Acc:HGNC:2765]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006952//defense response;GO:0019731//antibacterial humoral response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051673//membrane disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000164823	11.121	8.629	8.829	10.427	8.542	9.579	914	761	572	607	633	611	OSGIN2	oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0030308//negative regulation of cell growth;GO:0051321//meiotic cell cycle	--
ENSG00000164825	0	0	0	0	0	0	0	0	0	0	0	0	DEFB1	defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766]	Human Diseases;Environmental Information Processing	Infectious disease: bacterial;Membrane transport	ko05150//Staphylococcus aureus infection;ko02010//ABC transporters	K23125;K23125	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece;GO:1990742//microvesicle	GO:0005515//protein binding;GO:0031731//CCR6 chemokine receptor binding;GO:0042802//identical protein binding	GO:0002227//innate immune response in mucosa;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009617//response to bacterium;GO:0019731//antibacterial humoral response;GO:0019933//cAMP-mediated signaling;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0060474//positive regulation of flagellated sperm motility involved in capacitation;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000164828	31.854	31.352	28.591	25.693	28.72	38.535	1693	1695.5	1234	1057	1395	1302	SUN1	Sad1 and UNC84 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18587]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005521//lamin binding;GO:0043495//protein-membrane adaptor activity;GO:0140444//cytoskeleton-nuclear membrane anchor activity	GO:0006998//nuclear envelope organization;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0021817//nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration;GO:0030154//cell differentiation;GO:0051321//meiotic cell cycle;GO:0051642//centrosome localization;GO:0070197//meiotic attachment of telomere to nuclear envelope;GO:0090292//nuclear matrix anchoring at nuclear membrane	--
ENSG00000164830	14.081	10.818	9.21	6.831	8.466	8.165	758	546	409	280	379	351	OXR1	oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0006979//response to oxidative stress;GO:0007628//adult walking behavior;GO:0043524//negative regulation of neuron apoptotic process;GO:0051402//neuron apoptotic process;GO:0071447//cellular response to hydroperoxide;GO:1900408//negative regulation of cellular response to oxidative stress;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1903204//negative regulation of oxidative stress-induced neuron death	--
ENSG00000164841	0.138	0.076	0.135	0.104	0.018	0.084	18	10	13	10	2	8	TMEM74	transmembrane protein 74 [Source:HGNC Symbol;Acc:HGNC:26409]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0006914//autophagy;GO:0016236//macroautophagy	--
ENSG00000164849	7.229	6.537	8.432	9.065	8.156	10.666	285	257	195	264	270	306	GPR146	G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000164850	2.791	2.321	2.935	3.492	2.951	6.228	123	114	128	124	122	227	GPER1	G protein-coupled estrogen receptor 1 [Source:HGNC Symbol;Acc:HGNC:4485]	Organismal Systems;Human Diseases;Organismal Systems	Endocrine system;Drug resistance: antineoplastic;Endocrine system	ko04915//Estrogen signaling pathway;ko01522//Endocrine resistance;ko04929//GnRH secretion	K04246;K04246;K04246	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0032591//dendritic spine membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043198//dendritic shaft;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus;GO:0044327//dendritic spine head;GO:0045095//keratin filament;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0048786//presynaptic active zone;GO:0055037//recycling endosome;GO:0098686//hippocampal mossy fiber to CA3 synapse	GO:0003682//chromatin binding;GO:0003707//steroid hormone receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0030284//estrogen receptor activity;GO:1990239//steroid hormone binding	GO:0001934//positive regulation of protein phosphorylation;GO:0001956//positive regulation of neurotransmitter secretion;GO:0002376//immune system process;GO:0002695//negative regulation of leukocyte activation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010948//negative regulation of cell cycle process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019228//neuronal action potential;GO:0030154//cell differentiation;GO:0030263//apoptotic chromosome condensation;GO:0030264//nuclear fragmentation involved in apoptotic nuclear change;GO:0030335//positive regulation of cell migration;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0042311//vasodilation;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0045599//negative regulation of fat cell differentiation;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050728//negative regulation of inflammatory response;GO:0050769//positive regulation of neurogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0051055//negative regulation of lipid biosynthetic process;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051726//regulation of cell cycle;GO:0051898//negative regulation of protein kinase B signaling;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0071333//cellular response to glucose stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0071375//cellular response to peptide hormone stimulus;GO:0071389//cellular response to mineralocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000724//positive regulation of cardiac vascular smooth muscle cell differentiation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000164853	0	0	0	0	0	0	0	0	0	0	0	0	UNCX	UNC homeobox [Source:HGNC Symbol;Acc:HGNC:33194]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001502//cartilage condensation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0021516//dorsal spinal cord development;GO:0021889//olfactory bulb interneuron differentiation;GO:0030154//cell differentiation;GO:0035726//common myeloid progenitor cell proliferation;GO:0045595//regulation of cell differentiation"	Homeobox
ENSG00000164855	0.515	0.163	0.186	0.327	0.589	0.199	19.21	10.83	17.21	11	22.56	6.57	TMEM184A	transmembrane protein 184A [Source:HGNC Symbol;Acc:HGNC:28797]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0048471//perinuclear region of cytoplasm	GO:0008201//heparin binding	-	--
ENSG00000164867	0.234	0.242	0.215	0.307	0.378	0.228	19.49	22	12	19	26	15	NOS3	nitric oxide synthase 3 [Source:HGNC Symbol;Acc:HGNC:7876]	Metabolism;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Signal transduction;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine and metabolic disease;Signal transduction;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04071//Sphingolipid signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04370//VEGF signaling pathway;ko00330//Arginine and proline metabolism;ko00220//Arginine biosynthesis	K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242;K13242	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0030666//endocytic vesicle membrane	GO:0003785//actin monomer binding;GO:0004517//nitric-oxide synthase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0034617//tetrahydrobiopterin binding;GO:0034618//arginine binding;GO:0046870//cadmium ion binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0097110//scaffold protein binding	GO:0001525//angiogenesis;GO:0001542//ovulation from ovarian follicle;GO:0001701//in utero embryonic development;GO:0001974//blood vessel remodeling;GO:0002028//regulation of sodium ion transport;GO:0003057//regulation of the force of heart contraction by chemical signal;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0006527//arginine catabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0007005//mitochondrion organization;GO:0007263//nitric oxide mediated signal transduction;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0009408//response to heat;GO:0009725//response to hormone;GO:0010544//negative regulation of platelet activation;GO:0010628//positive regulation of gene expression;GO:0014740//negative regulation of muscle hyperplasia;GO:0014806//smooth muscle hyperplasia;GO:0019430//removal of superoxide radicals;GO:0030324//lung development;GO:0031284//positive regulation of guanylate cyclase activity;GO:0031644//regulation of nervous system process;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0034405//response to fluid shear stress;GO:0042311//vasodilation;GO:0043267//negative regulation of potassium ion transport;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043542//endothelial cell migration;GO:0044249//cellular biosynthetic process;GO:0045454//cell redox homeostasis;GO:0045747//positive regulation of Notch signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0045776//negative regulation of blood pressure;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048873//homeostasis of number of cells within a tissue;GO:0051346//negative regulation of hydrolase activity;GO:0051926//negative regulation of calcium ion transport;GO:0060412//ventricular septum morphogenesis;GO:0070168//negative regulation of biomineral tissue development;GO:0097746//blood vessel diameter maintenance;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000164871	0	0	0	0	0	0	0	0	0	0	0	0	SPAG11B	sperm associated antigen 11B [Source:HGNC Symbol;Acc:HGNC:14534]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006952//defense response;GO:0007283//spermatogenesis;GO:0042742//defense response to bacterium;GO:0051838//cytolysis by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000164877	2.024	2.373	3.123	2.081	2.654	1.718	130	153	148	99	144	80	MICALL2	MICAL like 2 [Source:HGNC Symbol;Acc:HGNC:29672]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21068	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0031005//filamin binding;GO:0031267//small GTPase binding;GO:0042805//actinin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0030041//actin filament polymerization;GO:0031175//neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0032456//endocytic recycling;GO:0034446//substrate adhesion-dependent cell spreading;GO:0070830//bicellular tight junction assembly;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000164879	0.14	0.251	0.152	0.113	0.099	0.116	5	9	4	3	3	3	CA3	carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016151//nickel cation binding;GO:0016791//phosphatase activity;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process;GO:0006979//response to oxidative stress;GO:0009617//response to bacterium;GO:0016311//dephosphorylation;GO:0045471//response to ethanol	--
ENSG00000164880	18.108	17.898	19.758	21.64	19.373	16.696	2507	2605	2113	2201	2370	1759	INTS1	integrator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24555]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0032039//integrator complex	-	GO:0016180//snRNA processing;GO:0034474//U2 snRNA 3'-end processing	--
ENSG00000164885	18.561	16.33	21.228	20.38	18.459	22.602	419	381	354	337	347	376	CDK5	cyclin dependent kinase 5 [Source:HGNC Symbol;Acc:HGNC:1774]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Development and regeneration;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04360//Axon guidance;ko05030//Cocaine addiction	K02090;K02090;K02090;K02090	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016533//protein kinase 5 complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005176//ErbB-2 class receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030549//acetylcholine receptor activator activity;GO:0043125//ErbB-3 class receptor binding;GO:0046875//ephrin receptor binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0051879//Hsp90 protein binding;GO:0099635//voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels;GO:0106310//protein serine kinase activity	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0001934//positive regulation of protein phosphorylation;GO:0001963//synaptic transmission, dopaminergic;GO:0006468//protein phosphorylation;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006913//nucleocytoplasmic transport;GO:0006915//apoptotic process;GO:0007005//mitochondrion organization;GO:0007049//cell cycle;GO:0007160//cell-matrix adhesion;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0007519//skeletal muscle tissue development;GO:0008045//motor neuron axon guidance;GO:0008306//associative learning;GO:0008542//visual learning;GO:0009611//response to wounding;GO:0014044//Schwann cell development;GO:0016079//synaptic vesicle exocytosis;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0016572//histone phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019233//sensory perception of pain;GO:0021537//telencephalon development;GO:0021549//cerebellum development;GO:0021695//cerebellar cortex development;GO:0021697//cerebellar cortex formation;GO:0021766//hippocampus development;GO:0021819//layer formation in cerebral cortex;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0022038//corpus callosum development;GO:0030182//neuron differentiation;GO:0030334//regulation of cell migration;GO:0030517//negative regulation of axon extension;GO:0030866//cortical actin cytoskeleton organization;GO:0030900//forebrain development;GO:0031175//neuron projection development;GO:0031397//negative regulation of protein ubiquitination;GO:0031914//negative regulation of synaptic plasticity;GO:0032092//positive regulation of protein binding;GO:0032801//receptor catabolic process;GO:0034352//positive regulation of glial cell apoptotic process;GO:0035249//synaptic transmission, glutamatergic;GO:0035418//protein localization to synapse;GO:0042220//response to cocaine;GO:0042501//serine phosphorylation of STAT protein;GO:0042981//regulation of apoptotic process;GO:0043113//receptor clustering;GO:0043525//positive regulation of neuron apoptotic process;GO:0045055//regulated exocytosis;GO:0045786//negative regulation of cell cycle;GO:0045860//positive regulation of protein kinase activity;GO:0045861//negative regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0046777//protein autophosphorylation;GO:0046826//negative regulation of protein export from nucleus;GO:0048148//behavioral response to cocaine;GO:0048167//regulation of synaptic plasticity;GO:0048488//synaptic vesicle endocytosis;GO:0048489//synaptic vesicle transport;GO:0048511//rhythmic process;GO:0048675//axon extension;GO:0048709//oligodendrocyte differentiation;GO:0048812//neuron projection morphogenesis;GO:0048813//dendrite morphogenesis;GO:0051301//cell division;GO:0051402//neuron apoptotic process;GO:0051726//regulation of cell cycle;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0061001//regulation of dendritic spine morphogenesis;GO:0070509//calcium ion import;GO:0090314//positive regulation of protein targeting to membrane;GO:0098883//synapse pruning;GO:0099533//positive regulation of presynaptic cytosolic calcium concentration;GO:0099703//induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration;GO:1901215//negative regulation of neuron death;GO:1901216//positive regulation of neuron death;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903076//regulation of protein localization to plasma membrane;GO:1903421//regulation of synaptic vesicle recycling;GO:1904646//cellular response to amyloid-beta;GO:2000251//positive regulation of actin cytoskeleton reorganization"	--
ENSG00000164889	536.453	582.13	601.773	692.441	671.651	644.874	30205	32100	25137	29212	31887	26259	SLC4A2	solute carrier family 4 member 2 [Source:HGNC Symbol;Acc:HGNC:11028]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Digestive system;Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04971//Gastric acid secretion	K13855;K13855;K13855;K13855	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0005452//inorganic anion exchanger activity;GO:0008509//anion transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0019899//enzyme binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006820//anion transport;GO:0007283//spermatogenesis;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0048565//digestive tract development;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0070175//positive regulation of enamel mineralization;GO:0097186//amelogenesis;GO:0098656//anion transmembrane transport	--
ENSG00000164893	0	0	0	0	0	0	0	0	0	0	0	0	SLC7A13	solute carrier family 7 member 13 [Source:HGNC Symbol;Acc:HGNC:23092]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0015179//L-amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0046982//protein heterodimerization activity	GO:0006865//amino acid transport;GO:0015810//aspartate transmembrane transport;GO:0015811//L-cystine transport;GO:0015813//L-glutamate transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000164896	15.21	15.842	17.064	18.066	19.632	20.073	540	584	457	494	602	535	FASTK	Fas activated serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:24676]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0033867//Fas-activated serine/threonine kinase activity	GO:0000963//mitochondrial RNA processing;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0016310//phosphorylation;GO:0043484//regulation of RNA splicing;GO:0044528//regulation of mitochondrial mRNA stability;GO:0097190//apoptotic signaling pathway	--
ENSG00000164897	26.419	25.729	30.626	37.024	36.237	35.376	687	680	586	727	765	663	TMUB1	transmembrane and ubiquitin like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21709]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000164898	1.601	2.236	1.389	2.709	0.861	2.498	33.67	47.26	21.58	42.21	15.3	38.23	FMC1	formation of mitochondrial complex V assembly factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:26946]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0050995//negative regulation of lipid catabolic process;GO:0061469//regulation of type B pancreatic cell proliferation	--
ENSG00000164900	0	0.079	0	0	0	0.036	0	3	0	0	0	1	GBX1	gastrulation brain homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4185]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007628//adult walking behavior;GO:0019230//proprioception;GO:0021522//spinal cord motor neuron differentiation;GO:0048663//neuron fate commitment;GO:0051960//regulation of nervous system development;GO:0097374//sensory neuron axon guidance"	Homeobox
ENSG00000164902	8.389	7.044	7.615	6.258	6.72	7.987	628	530	421	347	425	435	PHAX	phosphorylated adaptor for RNA export [Source:HGNC Symbol;Acc:HGNC:10241]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14291	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0043025//neuronal cell body;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015643//toxic substance binding;GO:0140262//mRNA cap binding complex binding	GO:0006408//snRNA export from nucleus;GO:0015031//protein transport;GO:0043489//RNA stabilization	--
ENSG00000164904	40.475	41.963	44.658	42.151	36.229	40.147	1792	1836	1425	1328	1339	1281	ALDH7A1	aldehyde dehydrogenase 7 family member A1 [Source:HGNC Symbol;Acc:HGNC:877]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00260//Glycine, serine and threonine metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism"	K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085;K14085	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004043//L-aminoadipate-semialdehyde dehydrogenase activity;GO:0005515//protein binding;GO:0008802//betaine-aldehyde dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"	GO:0006081//cellular aldehyde metabolic process;GO:0007605//sensory perception of sound;GO:0019285//glycine betaine biosynthetic process from choline;GO:0042426//choline catabolic process	--
ENSG00000164916	5.365	5.721	5.266	4.091	4.449	5.62	1173	1309	903	597	848	902	FOXK1	forkhead box K1 [Source:HGNC Symbol;Acc:HGNC:23480]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0071889//14-3-3 protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001678//cellular glucose homeostasis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0010507//negative regulation of autophagy;GO:0010906//regulation of glucose metabolic process;GO:0030154//cell differentiation;GO:0042594//response to starvation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061621//canonical glycolysis"	Fork_head
ENSG00000164919	81.324	78.615	90.028	108.903	76.057	83.83	935	912	764	934	749	706	COX6C	cytochrome c oxidase subunit 6C [Source:HGNC Symbol;Acc:HGNC:2285]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268;K02268	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration"	--
ENSG00000164920	0	0	0	0	0	0	0	0	0	0	0	0	OSR2	odd-skipped related transciption factor 2 [Source:HGNC Symbol;Acc:HGNC:15830]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001655//urogenital system development;GO:0001656//metanephros development;GO:0001823//mesonephros development;GO:0002062//chondrocyte differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0009792//embryo development ending in birth or egg hatching;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0033687//osteoblast proliferation;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0042474//middle ear morphogenesis;GO:0042476//odontogenesis;GO:0042733//embryonic digit morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//roof of mouth development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060322//head development;GO:0060349//bone morphogenesis;GO:0061029//eyelid development in camera-type eye;GO:0072498//embryonic skeletal joint development"	zf-C2H2
ENSG00000164924	194.244	178.191	182.001	184.626	183.784	205.707	8392	7810	5835	5859	6747	6416	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta [Source:HGNC Symbol;Acc:HGNC:12855]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle	K16197;K16197;K16197;K16197;K16197;K16197;K16197	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0031982//vesicle;GO:0042470//melanosome;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	GO:0003723//RNA binding;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0003016//respiratory system process;GO:0006468//protein phosphorylation;GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0008039//synaptic target recognition;GO:0010941//regulation of cell death;GO:0016310//phosphorylation;GO:0030324//lung development;GO:0034613//cellular protein localization;GO:0035148//tube formation;GO:0043066//negative regulation of apoptotic process;GO:0051683//establishment of Golgi localization;GO:0070371//ERK1 and ERK2 cascade;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0090128//regulation of synapse maturation;GO:0090168//Golgi reassembly;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	--
ENSG00000164929	1.065	1.209	0.691	0.843	0.971	1.231	62	71	24	36	43	52	BAALC	BAALC binder of MAP3K1 and KLF4 [Source:HGNC Symbol;Acc:HGNC:14333]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0045202//synapse	GO:0005515//protein binding	-	--
ENSG00000164930	42.81	37.243	34.983	26.473	28.574	31.113	3102	2675	1913	1393	1720	1691	FZD6	frizzled class receptor 6 [Source:HGNC Symbol;Acc:HGNC:4044]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376;K02376	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042813//Wnt-activated receptor activity	"GO:0001736//establishment of planar polarity;GO:0001843//neural tube closure;GO:0001942//hair follicle development;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030168//platelet activation;GO:0030901//midbrain development;GO:0033278//cell proliferation in midbrain;GO:0035567//non-canonical Wnt signaling pathway;GO:0035880//embryonic nail plate morphogenesis;GO:0042472//inner ear morphogenesis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0048105//establishment of body hair planar orientation;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904693//midbrain morphogenesis"	--
ENSG00000164932	8.904	12.264	7.909	2.069	3.466	3.133	171	232	129	38	64	40	CTHRC1	collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005109//frizzled binding;GO:0005201//extracellular matrix structural constituent;GO:0017147//Wnt-protein binding	"GO:0016477//cell migration;GO:0032092//positive regulation of protein binding;GO:0033690//positive regulation of osteoblast proliferation;GO:0043932//ossification involved in bone remodeling;GO:0045669//positive regulation of osteoblast differentiation;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060122//inner ear receptor cell stereocilium organization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090103//cochlea morphogenesis;GO:0090177//establishment of planar polarity involved in neural tube closure"	--
ENSG00000164933	4.618	5.009	4.654	4.58	5.473	4.316	268.25	299.13	196.62	182.42	248.35	186.69	SLC25A32	solute carrier family 25 member 32 [Source:HGNC Symbol;Acc:HGNC:29683]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0008517//folic acid transmembrane transporter activity;GO:0015230//FAD transmembrane transporter activity	GO:0006839//mitochondrial transport;GO:0006862//nucleotide transport;GO:0015884//folic acid transport;GO:0046655//folic acid metabolic process;GO:0055085//transmembrane transport;GO:1904947//folate import into mitochondrion;GO:1990548//mitochondrial FAD transmembrane transport	--
ENSG00000164934	11.235	12.914	9.384	8.566	8.898	10.551	451.75	485.87	290.38	266.58	291.65	288.31	DCAF13	DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:HGNC:24535]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0030054//cell junction;GO:0032040//small-subunit processome;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030331//estrogen receptor binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0016567//protein ubiquitination;GO:0042254//ribosome biogenesis"	--
ENSG00000164935	0	0	0	0	0	0	0	0	0	0	0	0	DCSTAMP	dendrocyte expressed seven transmembrane protein [Source:HGNC Symbol;Acc:HGNC:18549]	-	-	-	-	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding	GO:0002376//immune system process;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030316//osteoclast differentiation;GO:0034241//positive regulation of macrophage fusion;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0043011//myeloid dendritic cell differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0045780//positive regulation of bone resorption;GO:0061025//membrane fusion;GO:0071353//cellular response to interleukin-4;GO:0071356//cellular response to tumor necrosis factor;GO:0072675//osteoclast fusion	--
ENSG00000164938	4.47	4.365	4.965	3.64	3.474	4.365	521	511	427	314	342	370	TP53INP1	tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0016605//PML body;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0016209//antioxidant activity	"GO:0000045//autophagosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0009408//response to heat;GO:0010506//regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030336//negative regulation of cell migration;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048102//autophagic cell death;GO:0048147//negative regulation of fibroblast proliferation;GO:0051726//regulation of cell cycle;GO:0071361//cellular response to ethanol;GO:0071447//cellular response to hydroperoxide;GO:0072703//cellular response to methyl methanesulfonate;GO:0098869//cellular oxidant detoxification;GO:1904761//negative regulation of myofibroblast differentiation"	--
ENSG00000164941	14.531	10.451	10.961	8.517	8.128	9.919	567	494.01	297	283.91	357	344.77	INTS8	integrator complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:26048]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing	--
ENSG00000164944	13.504	8.325	8.52	7.122	7.764	7.729	1301	1054	801	668	810	663	VIRMA	vir like m6A methyltransferase associated [Source:HGNC Symbol;Acc:HGNC:24500]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0080009//mRNA methylation;GO:0110104//mRNA alternative polyadenylation	--
ENSG00000164946	0.249	0.222	0.216	0.146	0.211	0.292	36	35	25	17	28	25	FREM1	FRAS1 related extracellular matrix 1 [Source:HGNC Symbol;Acc:HGNC:23399]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K23380	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0007154//cell communication;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0097094//craniofacial suture morphogenesis	--
ENSG00000164949	85.104	80.346	84.586	68.835	71.444	74.275	3780	3591	2775	2262	2685	2409	GEM	GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0051233//spindle midzone;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0000278//mitotic cell cycle;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0051276//chromosome organization;GO:0051310//metaphase plate congression;GO:1901842//negative regulation of high voltage-gated calcium channel activity	--
ENSG00000164951	3.597	2.995	2.635	2.89	3.834	3.297	268	224	151	174	231	190	PDP1	pyruvate dehydrogenase phosphatase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:9279]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045253//pyruvate dehydrogenase (lipoamide) phosphatase complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:1904184//positive regulation of pyruvate dehydrogenase activity	--
ENSG00000164953	4.815	3.571	4.309	2.956	3.253	4.265	326	267	213	157	199	191	TMEM67	transmembrane protein 67 [Source:HGNC Symbol;Acc:HGNC:28396]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding;GO:0031005//filamin binding;GO:0051082//unfolded protein binding	GO:0010826//negative regulation of centrosome duplication;GO:0030030//cell projection organization;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0060271//cilium assembly	--
ENSG00000164961	19.697	20.911	18.8	15.137	16.185	15.881	1672	1497	1078	899	1160	992	WASHC5	WASH complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:28984]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18464	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0071203//WASH complex	GO:0005515//protein binding	GO:0001556//oocyte maturation;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0030041//actin filament polymerization;GO:0031503//protein-containing complex localization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0040038//polar body extrusion after meiotic divisions;GO:0043933//protein-containing complex subunit organization;GO:0051125//regulation of actin nucleation;GO:0090306//meiotic spindle assembly;GO:0097494//regulation of vesicle size;GO:0140285//endosome fission	--
ENSG00000164967	3.759	4.39	4.409	6.405	5.578	4.408	75	85	62	90	90	63	RPP25L	ribonuclease P/MRP subunit p25 like [Source:HGNC Symbol;Acc:HGNC:19909]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14525	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0001682//tRNA 5'-leader removal	--
ENSG00000164970	5.912	5.275	5.758	5.149	6.423	4.333	327	315	249	223	293	181	FAM219A	family with sequence similarity 219 member A [Source:HGNC Symbol;Acc:HGNC:19920]	-	-	-	-	-	-	-	--
ENSG00000164972	0.135	0.681	0.367	0	0.264	0.465	2	10	4	0	3	5	C9orf24	chromosome 9 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:19919]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0043014//alpha-tubulin binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0034622//cellular protein-containing complex assembly	--
ENSG00000164975	11.949	9.771	9.455	7.928	8.49	9.099	639	530	390	322	399	358	SNAPC3	small nuclear RNA activating complex polypeptide 3 [Source:HGNC Symbol;Acc:HGNC:11136]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body;GO:0019185//snRNA-activating protein complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003681//bent DNA binding;GO:0005515//protein binding	GO:0006366//transcription by RNA polymerase II;GO:0006383//transcription by RNA polymerase III;GO:0009301//snRNA transcription;GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III	--
ENSG00000164976	2.333	2.515	1.954	1.686	1.815	1.86	312	338	193	167	205	181	MYORG	myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048741//skeletal muscle fiber development;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000164978	9.375	11.543	11.359	10.203	7.783	9.388	186	230	167	152	132	134	NUDT2	nudix hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8049]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01518;K01518;K01518	GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004081//bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008796//bis(5'-nucleosyl)-tetraphosphatase activity;GO:0008803//bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity;GO:0016787//hydrolase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006167//AMP biosynthetic process;GO:0006754//ATP biosynthetic process;GO:0006915//apoptotic process;GO:0034599//cellular response to oxidative stress	--
ENSG00000164983	1.51	1.157	1.618	1.253	1.351	1.569	283	218	224	174	214	214	TMEM65	transmembrane protein 65 [Source:HGNC Symbol;Acc:HGNC:25203]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0003231//cardiac ventricle development;GO:1903779//regulation of cardiac conduction	--
ENSG00000164985	20.923	19.753	14.623	10.885	14.446	13.291	1265	1172	675	409	606	585	PSIP1	PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0034399//nuclear periphery;GO:0035327//transcriptionally active chromatin	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0097100//supercoiled DNA binding;GO:0140297//DNA-binding transcription factor binding	GO:0000395//mRNA 5'-splice site recognition;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006979//response to oxidative stress;GO:0009408//response to heat;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000164989	0.788	0.428	0.507	0.322	0.505	0.37	101	51	47	27	49	27	CCDC171	coiled-coil domain containing 171 [Source:HGNC Symbol;Acc:HGNC:29828]	-	-	-	-	-	-	-	--
ENSG00000165006	32.447	32.286	33.741	30.39	29.019	31.956	1677	1634	1280	1173	1264	1237	UBAP1	ubiquitin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:12461]	-	-	-	-	GO:0000813//ESCRT I complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0015031//protein transport;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	--
ENSG00000165023	0.094	0.187	0.08	0.427	0.549	0.016	8	16	5	14	12	1	DIRAS2	DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0007165//signal transduction	--
ENSG00000165025	0	0.01	0	0	0.034	0	0	1	0	0	3	0	SYK	spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Immune system;Immune system;Immune system;Development and regeneration;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04625//C-type lectin receptor signaling pathway	K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855;K05855	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019815//B cell receptor complex;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032009//early phagosome;GO:0032991//protein-containing complex;GO:0042101//T cell receptor complex	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016170//interleukin-15 receptor binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0035325//Toll-like receptor binding;GO:0042169//SH2 domain binding;GO:0043274//phospholipase binding;GO:0097110//scaffold protein binding	GO:0001525//angiogenesis;GO:0001775//cell activation;GO:0001819//positive regulation of cytokine production;GO:0001820//serotonin secretion;GO:0001945//lymph vessel development;GO:0002092//positive regulation of receptor internalization;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002281//macrophage activation involved in immune response;GO:0002283//neutrophil activation involved in immune response;GO:0002366//leukocyte activation involved in immune response;GO:0002376//immune system process;GO:0002554//serotonin secretion by platelet;GO:0002696//positive regulation of leukocyte activation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006468//protein phosphorylation;GO:0006606//protein import into nucleus;GO:0007159//leukocyte cell-cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0009887//animal organ morphogenesis;GO:0010543//regulation of platelet activation;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019370//leukotriene biosynthetic process;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031623//receptor internalization;GO:0032481//positive regulation of type I interferon production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032752//positive regulation of interleukin-3 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032928//regulation of superoxide anion generation;GO:0032930//positive regulation of superoxide anion generation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035556//intracellular signal transduction;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0038156//interleukin-3-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043306//positive regulation of mast cell degranulation;GO:0043313//regulation of neutrophil degranulation;GO:0043366//beta selection;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0045087//innate immune response;GO:0045579//positive regulation of B cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045780//positive regulation of bone resorption;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0046777//protein autophosphorylation;GO:0048514//blood vessel morphogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050764//regulation of phagocytosis;GO:0050778//positive regulation of immune response;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050853//B cell receptor signaling pathway;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051712//positive regulation of killing of cells of other organism;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0071226//cellular response to molecule of fungal origin;GO:0071396//cellular response to lipid;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0090237//regulation of arachidonic acid secretion;GO:0090330//regulation of platelet aggregation;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1990858//cellular response to lectin	--
ENSG00000165028	0.385	0.288	0.377	0.438	0.514	0.402	30	28	32	25	19	12	NIPSNAP3B	nipsnap homolog 3B [Source:HGNC Symbol;Acc:HGNC:23641]	-	-	-	-	GO:0005739//mitochondrion	-	-	--
ENSG00000165029	2.653	2	2.107	0.919	1.091	1.574	534	434	336	147	199	232	ABCA1	ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29]	Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Cardiovascular disease;Digestive system;Membrane transport;Digestive system	ko05417//Lipid and atherosclerosis;ko04979//Cholesterol metabolism;ko02010//ABC transporters;ko04975//Fat digestion and absorption	K05641;K05641;K05641;K05641	GO:0005768//endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0097708//intracellular vesicle	GO:0000166//nucleotide binding;GO:0005102//signaling receptor binding;GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005548//phospholipid transporter activity;GO:0008320//protein transmembrane transporter activity;GO:0015485//cholesterol binding;GO:0019905//syntaxin binding;GO:0031210//phosphatidylcholine binding;GO:0031267//small GTPase binding;GO:0034185//apolipoprotein binding;GO:0034186//apolipoprotein A-I binding;GO:0034188//apolipoprotein A-I receptor activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046623//sphingolipid floppase activity;GO:0051117//ATPase binding;GO:0090554//phosphatidylcholine floppase activity;GO:0090556//phosphatidylserine floppase activity;GO:0120020//cholesterol transfer activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140328//floppase activity;GO:0140359//ABC-type transporter activity	"GO:0002790//peptide secretion;GO:0006497//protein lipidation;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006911//phagocytosis, engulfment;GO:0007040//lysosome organization;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009306//protein secretion;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0016197//endosomal transport;GO:0023061//signal release;GO:0032367//intracellular cholesterol transport;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034380//high-density lipoprotein particle assembly;GO:0034616//response to laminar fluid shear stress;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0045332//phospholipid translocation;GO:0055085//transmembrane transport;GO:0055091//phospholipid homeostasis;GO:0060155//platelet dense granule organization;GO:0071222//cellular response to lipopolysaccharide;GO:0071300//cellular response to retinoic acid;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071806//protein transmembrane transport;GO:0090107//regulation of high-density lipoprotein particle assembly;GO:0090108//positive regulation of high-density lipoprotein particle assembly;GO:0099039//sphingolipid translocation;GO:0120009//intermembrane lipid transfer;GO:0140115//export across plasma membrane"	--
ENSG00000165030	7.906	8.076	7.052	7.126	7.192	8.996	337	346	222	225	259	279	NFIL3	"nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001779//natural killer cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006955//immune response;GO:0007623//circadian rhythm;GO:0010628//positive regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0071353//cellular response to interleukin-4"	TF_bZIP
ENSG00000165046	5.941	6.01	4.514	2.687	3.61	3.718	176	190	106	76	89	88	LETM2	leucine zipper and EF-hand containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:14648]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0043022//ribosome binding	GO:0006875//cellular metal ion homeostasis	--
ENSG00000165055	9.526	11.644	11.587	11.24	10.818	9.185	508.07	635.09	488.96	418.61	456.71	408.58	METTL2B	"methyltransferase 2B, methylcytidine [Source:HGNC Symbol;Acc:HGNC:18272]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016427//tRNA (cytosine) methyltransferase activity;GO:0016740//transferase activity;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000165059	0	0	0	0	0	0	0	0	0	0	0	0	PRKACG	protein kinase cAMP-activated catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:9382]	Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Sensory system;Infectious disease: viral;Signal transduction;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Cancer: overview;Immune system;Substance dependence;Cellular community - eukaryotes;Infectious disease: parasitic;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Nervous system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Endocrine system;Nervous system;Nervous system;Nervous system;Endocrine system;Endocrine system;Endocrine system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Endocrine system;Substance dependence;Nervous system;Aging;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Excretory system;Infectious disease: bacterial;Substance dependence;Excretory system	"ko05200//Pathways in cancer;ko04740//Olfactory transduction;ko05165//Human papillomavirus infection;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04530//Tight junction;ko05146//Amoebiasis;ko04310//Wnt signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04340//Hedgehog signaling pathway;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko05110//Vibrio cholerae infection;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345;K04345	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0097546//ciliary base	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0106310//protein serine kinase activity	GO:0003091//renal water homeostasis;GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0010737//protein kinase A signaling;GO:0016310//phosphorylation;GO:0034380//high-density lipoprotein particle assembly	--
ENSG00000165060	4.412	7.53	4.723	6.153	6.864	6.012	136.88	180.73	101.07	117.84	144.85	111.57	FXN	frataxin [Source:HGNC Symbol;Acc:HGNC:3951]	Metabolism	Metabolism of cofactors and vitamins	ko00860//Porphyrin metabolism	K19054	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1990221//L-cysteine desulfurase complex;GO:1990229//iron-sulfur cluster assembly complex	"GO:0004322//ferroxidase activity;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0034986//iron chaperone activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006119//oxidative phosphorylation;GO:0006783//heme biosynthetic process;GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0007005//mitochondrion organization;GO:0007628//adult walking behavior;GO:0008284//positive regulation of cell population proliferation;GO:0009060//aerobic respiration;GO:0009792//embryo development ending in birth or egg hatching;GO:0010039//response to iron ion;GO:0010722//regulation of ferrochelatase activity;GO:0016226//iron-sulfur cluster assembly;GO:0016540//protein autoprocessing;GO:0018283//iron incorporation into metallo-sulfur cluster;GO:0019230//proprioception;GO:0030307//positive regulation of cell growth;GO:0040015//negative regulation of multicellular organism growth;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0046621//negative regulation of organ growth;GO:0051349//positive regulation of lyase activity;GO:0055072//iron ion homeostasis;GO:0070301//cellular response to hydrogen peroxide;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:1904231//positive regulation of succinate dehydrogenase activity;GO:1904234//positive regulation of aconitate hydratase activity	--
ENSG00000165061	0.059	0.177	0	0	0.051	0	3	5	0	0	2	0	ZMAT4	zinc finger matrin-type 4 [Source:HGNC Symbol;Acc:HGNC:25844]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	-	--
ENSG00000165066	0	0	0	0	0	0	0	0	0	0	0	0	NKX6-3	NK6 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:26328]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001709//cell fate determination;GO:0002067//glandular epithelial cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000165071	0	0	0	0	0	0	0	0	0	0	0	0	TMEM71	transmembrane protein 71 [Source:HGNC Symbol;Acc:HGNC:26572]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000165072	7.654	6.928	4.169	7.478	7.748	7.613	532	484	214	385	455	385	MAMDC2	MAM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23673]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000165076	0	0	0	0	0	0	0	0	0	0	0	0	PRSS37	serine protease 37 [Source:HGNC Symbol;Acc:HGNC:29211]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0004252//serine-type endopeptidase activity	GO:0006508//proteolysis;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0016477//cell migration;GO:0051604//protein maturation;GO:0070613//regulation of protein processing;GO:1905516//positive regulation of fertilization;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000165078	0	0.077	0.032	0	0	0.099	0	3	1	0	0	3	CPA6	carboxypeptidase A6 [Source:HGNC Symbol;Acc:HGNC:17245]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000165084	0.788	0.525	0.556	0.364	0.527	0.559	41	27	22	14	24	21	C8orf34	chromosome 8 open reading frame 34 [Source:HGNC Symbol;Acc:HGNC:30905]	-	-	-	-	-	-	-	--
ENSG00000165091	0.022	0	0.059	0.028	0.056	0.012	1	0	4	2	3	1	TMC1	transmembrane channel like 1 [Source:HGNC Symbol;Acc:HGNC:16513]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032426//stereocilium tip	GO:0005245//voltage-gated calcium channel activity;GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0007605//sensory perception of sound;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060005//vestibular reflex;GO:0060117//auditory receptor cell development;GO:0070588//calcium ion transmembrane transport;GO:1903169//regulation of calcium ion transmembrane transport	--
ENSG00000165092	75.776	77.685	65.869	75.955	76.96	80.108	3096	3229	2115	2446	2742	2454	ALDH1A1	aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K07249;K07249	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon;GO:0042995//cell projection;GO:0045202//synapse;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0001758//retinal dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0005096//GTPase activator activity;GO:0005497//androgen binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0018479//benzaldehyde dehydrogenase (NAD+) activity;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0043878//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity;GO:0051287//NAD binding;GO:0106373//3-deoxyglucosone dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0030392//fructosamine catabolic process;GO:0036438//maintenance of lens transparency;GO:0042572//retinol metabolic process;GO:0050790//regulation of catalytic activity;GO:0110095//cellular detoxification of aldehyde;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000165097	7.944	6.783	7.798	6.061	6.509	5.737	711	641	527	372	481	383	KDM1B	lysine demethylase 1B [Source:HGNC Symbol;Acc:HGNC:21577]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding;GO:0140682//histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006349//regulation of gene expression by genetic imprinting;GO:0034720//histone H3-K4 demethylation;GO:0043046//DNA methylation involved in gamete generation;GO:0044030//regulation of DNA methylation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000165102	12.08	11.671	11.21	11.973	12	10.753	1171	1132	750	844	974	743.9	HGSNAT	heparan-alpha-glucosaminide N-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:26527]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K10532;K10532;K10532	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0015019//heparan-alpha-glucosaminide N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0007041//lysosomal transport;GO:0051259//protein complex oligomerization	--
ENSG00000165105	1.315	0.918	0.701	0.935	1.162	1.13	72.67	48.31	33.93	40	49.44	48.78	RASEF	RAS and EF-hand domain containing [Source:HGNC Symbol;Acc:HGNC:26464]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	-	--
ENSG00000165113	3.504	2.275	2.609	3.027	2.338	3.355	120	80	67	76	69	88	GKAP1	G kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:17496]	-	-	-	-	GO:0005794//Golgi apparatus	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0046628//positive regulation of insulin receptor signaling pathway	--
ENSG00000165115	2.996	2.578	1.863	1.31	2.376	1.976	239	172	103	47	124	64	KIF27	kinesin family member 27 [Source:HGNC Symbol;Acc:HGNC:18632]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007018//microtubule-based movement;GO:0021591//ventricular system development;GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000165118	0.293	0.369	0.529	0.225	0.393	0.16	15	19	20	8	17	5	C9orf64	chromosome 9 open reading frame 64 [Source:HGNC Symbol;Acc:HGNC:28144]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006400//tRNA modification;GO:0008150//biological_process;GO:0101030//tRNA-guanine transglycosylation	--
ENSG00000165119	360.12	348.751	353.282	305.75	310.596	352.948	15101	14665	10811	9496	11021	10659	HNRNPK	heterogeneous nuclear ribonucleoprotein K [Source:HGNC Symbol;Acc:HGNC:5044]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko03040//Spliceosome	K12886;K12886;K12886	GO:0000785//chromatin;GO:0002102//podosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007165//signal transduction;GO:0008380//RNA splicing;GO:0010468//regulation of gene expression;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:1902165//regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1905599//positive regulation of low-density lipoprotein receptor activity"	--
ENSG00000165120	0	0	0	0	0	0	0	0	0	0	0	0	SSMEM1	serine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29580]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000165124	0.549	0.575	0.423	0.459	0.766	0.753	139	133	73	86	126	134	SVEP1	"sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15985]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003682//chromatin binding;GO:0005509//calcium ion binding	GO:0001945//lymph vessel development;GO:0003017//lymph circulation;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0010467//gene expression;GO:0036303//lymph vessel morphogenesis;GO:0048014//Tie signaling pathway;GO:0120193//tight junction organization	--
ENSG00000165125	0	0	0	0	0	0	0	0	0	0	0	0	TRPV6	transient receptor potential cation channel subfamily V member 6 [Source:HGNC Symbol;Acc:HGNC:14006]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04970//Salivary secretion;ko04978//Mineral absorption	K04975;K04975	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0034704//calcium channel complex	GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0034220//ion transmembrane transport;GO:0035898//parathyroid hormone secretion;GO:0051592//response to calcium ion;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098703//calcium ion import across plasma membrane	--
ENSG00000165131	0	0.067	0	0	0	0	0	1	0	0	0	0	LLCFC1	LLLL and CFNLAS motif containing 1 [Source:HGNC Symbol;Acc:HGNC:21750]	-	-	-	-	GO:0005576//extracellular region	-	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization	--
ENSG00000165138	7.791	6.659	7.854	8.044	7.657	6.632	948	871	709	760	868	667	ANKS6	ankyrin repeat and sterile alpha motif domain containing 6 [Source:HGNC Symbol;Acc:HGNC:26724]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection;GO:0097543//ciliary inversin compartment	GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001822//kidney development;GO:0007368//determination of left/right symmetry;GO:0007507//heart development	--
ENSG00000165140	0.663	0.972	0.399	0.728	1.053	0.339	15	22	9	15	27	7	FBP1	fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine system;Signal transduction;Global and overview maps;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K03841;K03841;K03841;K03841;K03841;K03841;K03841;K03841	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016208//AMP binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0048029//monosaccharide binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0005975//carbohydrate metabolic process;GO:0005986//sucrose biosynthetic process;GO:0006000//fructose metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006094//gluconeogenesis;GO:0006111//regulation of gluconeogenesis;GO:0008152//metabolic process;GO:0016311//dephosphorylation;GO:0030308//negative regulation of cell growth;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0032869//cellular response to insulin stimulus;GO:0045820//negative regulation of glycolytic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:0071286//cellular response to magnesium ion;GO:0071466//cellular response to xenobiotic stimulus"	--
ENSG00000165152	22.206	22.255	24.983	25.896	26.148	26.739	1946	1961	1617	1681	1936	1705	PGAP4	post-GPI attachment to proteins GalNAc transferase 4 [Source:HGNC Symbol;Acc:HGNC:28180]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000165156	18.596	11.878	12.002	10.521	11.684	13.514	1477.95	1033	775	607	826	835	ZHX1	zinc fingers and homeoboxes 1 [Source:HGNC Symbol;Acc:HGNC:12871]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	Homeobox
ENSG00000165164	0.475	0.14	0.206	0.202	0.057	0.02	51	29	18	14	10	2	CFAP47	cilia and flagella associated protein 47 [Source:HGNC Symbol;Acc:HGNC:26708]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097224//sperm connecting piece	GO:0005515//protein binding	GO:0007288//sperm axoneme assembly	--
ENSG00000165168	0.092	0.161	0.365	0.161	0.249	0.143	7	14	11	9	17	9	CYBB	cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Immune system;Transport and catabolism;Cardiovascular disease;Cardiovascular disease;Immune system;Cell growth and death;Infectious disease: parasitic;Signal transduction;Immune system;Endocrine and metabolic disease;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko04613//Neutrophil extracellular trap formation;ko04145//Phagosome;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis;ko05140//Leishmaniasis;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04216//Ferroptosis	K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421;K21421	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030670//phagocytic vesicle membrane;GO:0035579//specific granule membrane;GO:0043020//NADPH oxidase complex;GO:0043025//neuronal cell body;GO:0045335//phagocytic vesicle;GO:0070821//tertiary granule membrane;GO:0097038//perinuclear endoplasmic reticulum	GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0050660//flavin adenine dinucleotide binding	GO:0006801//superoxide metabolic process;GO:0006811//ion transport;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0022900//electron transport chain;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0045730//respiratory burst;GO:0045766//positive regulation of angiogenesis;GO:0050665//hydrogen peroxide biosynthetic process;GO:0071276//cellular response to cadmium ion;GO:0071361//cellular response to ethanol;GO:0071456//cellular response to hypoxia;GO:0072593//reactive oxygen species metabolic process;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:1904044//response to aldosterone;GO:1904845//cellular response to L-glutamine;GO:1990776//response to angiotensin	--
ENSG00000165169	17.902	15.86	14.301	13.381	11.98	15.988	785	696	464	433	433	519	DYNLT3	dynein light chain Tctex-type 3 [Source:HGNC Symbol;Acc:HGNC:11694]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K10420	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0061673//mitotic spindle astral microtubule"	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0045931//positive regulation of mitotic cell cycle;GO:0051301//cell division	--
ENSG00000165171	1.203	1.977	2.478	2.188	2.599	1.896	23	38	35	31	42	24	METTL27	methyltransferase like 27 [Source:HGNC Symbol;Acc:HGNC:19068]	-	-	-	-	-	GO:0005515//protein binding;GO:0008168//methyltransferase activity	-	--
ENSG00000165175	9.059	9.01	8.192	9.689	9.765	12.08	565	555	402	435	513	542	MID1IP1	MID1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20715]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0007026//negative regulation of microtubule depolymerization;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0046890//regulation of lipid biosynthetic process;GO:0051258//protein polymerization;GO:0051351//positive regulation of ligase activity	--
ENSG00000165181	0	0.01	0	0	0	0	0	1	0	0	0	0	SHOC1	shortage in chiasmata 1 [Source:HGNC Symbol;Acc:HGNC:26535]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0007131//reciprocal meiotic recombination;GO:0051321//meiotic cell cycle	--
ENSG00000165182	0	0.062	0	0	0.074	0	0	2	0	0	2	0	CXorf58	chromosome X open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:26356]	-	-	-	-	-	-	-	--
ENSG00000165185	8.254	6.396	6.182	3.578	4.594	4.522	1387	1050	740	477	635	560	KIAA1958	KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000165186	0.019	0.026	0.015	0.03	0.031	0.041	5	7	3	6	7	8	PTCHD1	patched domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26392]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0003674//molecular_function	GO:0007224//smoothened signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007614//short-term memory;GO:0007616//long-term memory;GO:0021794//thalamus development;GO:0035176//social behavior;GO:0050890//cognition;GO:0098976//excitatory chemical synaptic transmission;GO:0098977//inhibitory chemical synaptic transmission	--
ENSG00000165188	0	0	0	0	0	0	0	0	0	0	0	0	RNF183	ring finger protein 183 [Source:HGNC Symbol;Acc:HGNC:28721]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033106//cis-Golgi network membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0034976//response to endoplasmic reticulum stress;GO:0051865//protein autoubiquitination;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000165192	0	0	0.024	0	0	0	0	0	1	0	0	0	ASB11	ankyrin repeat and SOCS box containing 11 [Source:HGNC Symbol;Acc:HGNC:17186]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0045732//positive regulation of protein catabolic process	--
ENSG00000165194	0.505	0.499	0.517	0.484	0.494	0.398	91	88	74	64	77	49	PCDH19	protocadherin 19 [Source:HGNC Symbol;Acc:HGNC:14270]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007420//brain development	--
ENSG00000165195	2.811	2.159	2.074	3.065	2.224	2.494	152	159	96	128	118	116	PIGA	phosphatidylinositol glycan anchor biosynthesis class A [Source:HGNC Symbol;Acc:HGNC:8957]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03857;K03857	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity	GO:0006506//GPI anchor biosynthetic process;GO:0006629//lipid metabolic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000165197	0	0.093	0.063	0.094	0.028	0.096	0	4	2	3	1	3	VEGFD	vascular endothelial growth factor D [Source:HGNC Symbol;Acc:HGNC:3708]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes;Endocrine system;Signal transduction;Endocrine and metabolic disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04926//Relaxin signaling pathway;ko04668//TNF signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications	K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449;K05449	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen	GO:0005161//platelet-derived growth factor receptor binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0043185//vascular endothelial growth factor receptor 3 binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0030154//cell differentiation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051781//positive regulation of cell division;GO:0060754//positive regulation of mast cell chemotaxis;GO:0071542//dopaminergic neuron differentiation	--
ENSG00000165202	0	0	0	0	0	0	0	0	0	0	0	0	OR1Q1	olfactory receptor family 1 subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:8223]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000165204	0	0	0	0	0	0	0	0	0	0	0	0	OR1K1	olfactory receptor family 1 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:8212]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000165209	15.557	13.377	14.899	12.872	12.689	17.032	1058	924	745	624	773	823	STRBP	spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007638//mechanosensory behavior;GO:0030154//cell differentiation	--
ENSG00000165215	12.753	13.516	14.808	13.538	13.303	12.378	337	359	289	265	297	238	CLDN3	claudin 3 [Source:HGNC Symbol;Acc:HGNC:2045]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0043296//apical junction complex;GO:0070160//tight junction	GO:0004888//transmembrane signaling receptor activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0003382//epithelial cell morphogenesis;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014045//establishment of endothelial blood-brain barrier;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0022604//regulation of cell morphogenesis;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0034331//cell junction maintenance;GO:0035633//maintenance of blood-brain barrier;GO:0045471//response to ethanol;GO:0061045//negative regulation of wound healing;GO:0070830//bicellular tight junction assembly;GO:0090303//positive regulation of wound healing;GO:0090559//regulation of membrane permeability;GO:0150111//regulation of transepithelial transport;GO:1901890//positive regulation of cell junction assembly;GO:1903348//positive regulation of bicellular tight junction assembly;GO:1905050//positive regulation of metallopeptidase activity	--
ENSG00000165219	10.471	9.386	10.064	6.817	8.623	8.927	1185	1047	822	621	805	787	GAPVD1	GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0031267//small GTPase binding;GO:0032794//GTPase activating protein binding;GO:0045296//cadherin binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016192//vesicle-mediated transport;GO:0043087//regulation of GTPase activity;GO:0051223//regulation of protein transport	--
ENSG00000165233	5.568	4.096	5.809	6.677	7.5	5.796	109	83	90	100	123	87	CARD19	caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0050700//CARD domain binding	GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000165238	17.042	17.968	19.753	21.592	22.513	21.565	1827	2000	1538	1689	2057	1672	WNK2	WNK lysine deficient protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14542]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019869//chloride channel inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0010766//negative regulation of sodium ion transport;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:0050801//ion homeostasis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000165240	3.868	3.741	3.921	2.444	3.042	3.149	575	531	410	254	355	347	ATP7A	ATPase copper transporting alpha [Source:HGNC Symbol;Acc:HGNC:869]	Human Diseases;Organismal Systems	Drug resistance: antineoplastic;Digestive system	ko01524//Platinum drug resistance;ko04978//Mineral absorption	K17686;K17686	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030140//trans-Golgi network transport vesicle;GO:0030141//secretory granule;GO:0030424//axon;GO:0030425//dendrite;GO:0030670//phagocytic vesicle membrane;GO:0031252//cell leading edge;GO:0031526//brush border membrane;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0033162//melanosome membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005375//copper ion transmembrane transporter activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016532//superoxide dismutase copper chaperone activity;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0031267//small GTPase binding;GO:0032767//copper-dependent protein binding;GO:0043682//P-type divalent copper transporter activity;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0140581//P-type monovalent copper transporter activity;GO:1903136//cuprous ion binding	GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0001974//blood vessel remodeling;GO:0002082//regulation of oxidative phosphorylation;GO:0006568//tryptophan metabolic process;GO:0006584//catecholamine metabolic process;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006825//copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0007005//mitochondrion organization;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0007626//locomotory behavior;GO:0010041//response to iron(III) ion;GO:0010042//response to manganese ion;GO:0010043//response to zinc ion;GO:0010273//detoxification of copper ion;GO:0010288//response to lead ion;GO:0010468//regulation of gene expression;GO:0010592//positive regulation of lamellipodium assembly;GO:0015677//copper ion import;GO:0018205//peptidyl-lysine modification;GO:0019430//removal of superoxide radicals;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021860//pyramidal neuron development;GO:0021954//central nervous system neuron development;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0031069//hair follicle morphogenesis;GO:0032773//positive regulation of tyrosinase activity;GO:0034760//negative regulation of iron ion transmembrane transport;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042093//T-helper cell differentiation;GO:0042414//epinephrine metabolic process;GO:0042415//norepinephrine metabolic process;GO:0042417//dopamine metabolic process;GO:0042428//serotonin metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0043473//pigmentation;GO:0043588//skin development;GO:0045793//positive regulation of cell size;GO:0046688//response to copper ion;GO:0048023//positive regulation of melanin biosynthetic process;GO:0048251//elastic fiber assembly;GO:0048286//lung alveolus development;GO:0048812//neuron projection morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0051542//elastin biosynthetic process;GO:0055070//copper ion homeostasis;GO:0060003//copper ion export;GO:0071230//cellular response to amino acid stimulus;GO:0071236//cellular response to antibiotic;GO:0071276//cellular response to cadmium ion;GO:0071279//cellular response to cobalt ion;GO:0071280//cellular response to copper ion;GO:0071281//cellular response to iron ion;GO:0071284//cellular response to lead ion;GO:0071456//cellular response to hypoxia;GO:1903036//positive regulation of response to wounding;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1904959//regulation of cytochrome-c oxidase activity	--
ENSG00000165244	0.418	0.364	0.39	0.318	0.418	0.611	32	28	22	18	27	34	ZNF367	zinc finger protein 367 [Source:HGNC Symbol;Acc:HGNC:18320]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000165246	7.535	7.108	7.02	5.877	9.421	6.735	840.22	768.68	599.35	428.53	580.68	549.66	NLGN4Y	neuroligin 4 Y-linked [Source:HGNC Symbol;Acc:HGNC:15529]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07378	"GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0089717//spanning component of membrane;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane;GO:0098983//symmetric, GABA-ergic, inhibitory synapse;GO:0098984//neuron to neuron synapse;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0050839//cell adhesion molecule binding;GO:0097110//scaffold protein binding	GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007612//learning;GO:0035176//social behavior;GO:0048488//synaptic vesicle endocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0071625//vocalization behavior;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0099054//presynapse assembly	--
ENSG00000165259	0.893	1.009	0.811	0.454	0.919	0.533	87	106	77	44	58	34	HDX	highly divergent homeobox [Source:HGNC Symbol;Acc:HGNC:26411]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	GO:0006357//regulation of transcription by RNA polymerase II	Homeobox
ENSG00000165264	13.029	11.546	12.604	15.812	13.455	16.301	313	287	225	278	278	288	NDUFB6	NADH:ubiquinone oxidoreductase subunit B6 [Source:HGNC Symbol;Acc:HGNC:7701]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962;K03962	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000165269	0.076	0.209	0	0.023	0.19	0.087	2	8	0	1	8	3	AQP7	aquaporin 7 [Source:HGNC Symbol;Acc:HGNC:640]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko03320//PPAR signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K08771;K08771	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015267//channel activity	GO:0006833//water transport;GO:0015793//glycerol transport;GO:0055085//transmembrane transport;GO:0071918//urea transmembrane transport	--
ENSG00000165271	8.418	8.041	9.642	8.684	8.986	9.033	844	805	714	645	760	659	NOL6	nucleolar protein 6 [Source:HGNC Symbol;Acc:HGNC:19910]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14544	GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0032040//small-subunit processome;GO:0032545//CURI complex;GO:0034456//UTP-C complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0006409//tRNA export from nucleus	--
ENSG00000165272	1.506	1.34	0.644	0.25	1.126	0.782	57	51	18	7	36	15	AQP3	aquaporin 3 (Gill blood group) [Source:HGNC Symbol;Acc:HGNC:636]	Organismal Systems	Excretory system	ko04962//Vasopressin-regulated water reabsorption	K09876	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015267//channel activity;GO:0042802//identical protein binding	GO:0002684//positive regulation of immune system process;GO:0003091//renal water homeostasis;GO:0006833//water transport;GO:0015793//glycerol transport;GO:0015840//urea transport;GO:0032526//response to retinoic acid;GO:0033280//response to vitamin D;GO:0042476//odontogenesis;GO:0045616//regulation of keratinocyte differentiation;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0070295//renal water absorption;GO:0071456//cellular response to hypoxia;GO:0071918//urea transmembrane transport;GO:0090650//cellular response to oxygen-glucose deprivation	--
ENSG00000165275	2.066	1.954	1.358	2.08	1.621	1.976	86	73	40	47	58.96	63	TRMT10B	tRNA methyltransferase 10B [Source:HGNC Symbol;Acc:HGNC:26454]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0000049//tRNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0016740//transferase activity;GO:0052905//tRNA (guanine(9)-N(1))-methyltransferase activity	GO:0002939//tRNA N1-guanine methylation;GO:0032259//methylation;GO:0045039//protein insertion into mitochondrial inner membrane	--
ENSG00000165280	124.677	131.294	136.93	134.501	134.869	123.527	9304	9796	7591	7526	8544	6728	VCP	valosin containing protein [Source:HGNC Symbol;Acc:HGNC:12666]	Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Infectious disease: bacterial"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05134//Legionellosis	K13525;K13525;K13525;K13525	GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0032991//protein-containing complex;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0035861//site of double-strand break;GO:0036513//Derlin-1 retrotranslocation complex;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:1904813//ficolin-1-rich granule lumen;GO:1904949//ATPase complex;GO:1990730//VCP-NSFL1C complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035800//deubiquitinase activator activity;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0042288//MHC class I protein binding;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044877//protein-containing complex binding;GO:1904288//BAT3 complex binding;GO:1990381//ubiquitin-specific protease binding	"GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006734//NADH metabolic process;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010498//proteasomal protein catabolic process;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0016236//macroautophagy;GO:0016567//protein ubiquitination;GO:0019079//viral genome replication;GO:0019985//translesion synthesis;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0034605//cellular response to heat;GO:0035617//stress granule disassembly;GO:0036297//interstrand cross-link repair;GO:0036503//ERAD pathway;GO:0042981//regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045184//establishment of protein localization;GO:0045732//positive regulation of protein catabolic process;GO:0045879//negative regulation of smoothened signaling pathway;GO:0046034//ATP metabolic process;GO:0050807//regulation of synapse organization;GO:0051228//mitotic spindle disassembly;GO:0061857//endoplasmic reticulum stress-induced pre-emptive quality control;GO:0070842//aggresome assembly;GO:0071712//ER-associated misfolded protein catabolic process;GO:0072389//flavin adenine dinucleotide catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097352//autophagosome maturation;GO:0106300//protein-DNA covalent cross-linking repair;GO:1903006//positive regulation of protein K63-linked deubiquitination;GO:1903007//positive regulation of Lys63-specific deubiquitinase activity;GO:1903715//regulation of aerobic respiration;GO:1903843//cellular response to arsenite ion;GO:1903862//positive regulation of oxidative phosphorylation;GO:1905634//regulation of protein localization to chromatin;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000158//positive regulation of ubiquitin-specific protease activity;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000165282	15.492	15.927	17.451	17.556	17.371	17.198	1063	1080	867	892	1014	890	PIGO	phosphatidylinositol glycan anchor biosynthesis class O [Source:HGNC Symbol;Acc:HGNC:23215]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05288;K05288	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051377//mannose-ethanolamine phosphotransferase activity"	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000165283	39.813	46.687	41.824	48.911	44.226	50.576	1122	1323	867	1020	1053	1033	STOML2	stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559]	-	-	-	-	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane;GO:0042101//T cell receptor complex;GO:0045121//membrane raft	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0051020//GTPase binding;GO:1901612//cardiolipin binding	"GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0007005//mitochondrion organization;GO:0010876//lipid localization;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0032743//positive regulation of interleukin-2 production;GO:0034982//mitochondrial protein processing;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0050852//T cell receptor signaling pathway;GO:0051259//protein complex oligomerization;GO:0090297//positive regulation of mitochondrial DNA replication;GO:1900210//positive regulation of cardiolipin metabolic process;GO:1990046//stress-induced mitochondrial fusion"	--
ENSG00000165288	2.653	1.659	1.713	1.279	1.457	1.856	711	447	339	254	330	362	BRWD3	bromodomain and WD repeat domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17342]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape	--
ENSG00000165300	5.945	4.853	6.779	7.223	6.948	7.335	689	553	559	594	660	606	SLITRK5	SLIT and NTRK like family member 5 [Source:HGNC Symbol;Acc:HGNC:20295]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005515//protein binding	GO:0007268//chemical synaptic transmission;GO:0007409//axonogenesis;GO:0007625//grooming behavior;GO:0009410//response to xenobiotic stimulus;GO:0021756//striatum development;GO:0030534//adult behavior;GO:0043588//skin development;GO:0048813//dendrite morphogenesis;GO:0051965//positive regulation of synapse assembly;GO:0072359//circulatory system development;GO:1905606//regulation of presynapse assembly	--
ENSG00000165304	1.756	2.147	1.636	1.35	0.747	1.437	82	109	56	49	31	51	MELK	maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0008283//cell population proliferation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030097//hemopoiesis;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0061351//neural precursor cell proliferation	--
ENSG00000165309	1.668	1.737	1.927	0.482	1.123	0.617	90	97	65	21	47	24	ARMC3	armadillo repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:30964]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000165312	4.248	4.356	4.822	4.079	4.112	4.895	291	300	244	207	238	244	OTUD1	OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346]	-	-	-	-	-	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0070536//protein K63-linked deubiquitination	--
ENSG00000165322	8.804	5.66	5.027	4.868	5.577	6.557	778	583	384	373	485	493	ARHGAP12	Rho GTPase activating protein 12 [Source:HGNC Symbol;Acc:HGNC:16348]	-	-	-	-	GO:0001891//phagocytic cup;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0002011//morphogenesis of an epithelial sheet;GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051058//negative regulation of small GTPase mediated signal transduction"	--
ENSG00000165323	0.477	0.465	0.343	0.39	0.609	0.578	193	189	102	117	208	170	FAT3	FAT atypical cadherin 3 [Source:HGNC Symbol;Acc:HGNC:23112]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite	GO:0005509//calcium ion binding	GO:0000904//cell morphogenesis involved in differentiation;GO:0001764//neuron migration;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0010842//retina layer formation;GO:0098609//cell-cell adhesion;GO:2000171//negative regulation of dendrite development	--
ENSG00000165325	0.077	0.097	0.139	0.236	0.034	0.129	3	4	3	6	1	2	DEUP1	deuterosome assembly protein 1 [Source:HGNC Symbol;Acc:HGNC:26344]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098536//deuterosome	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007099//centriole replication;GO:0030030//cell projection organization;GO:0098535//de novo centriole assembly involved in multi-ciliated epithelial cell differentiation;GO:1903251//multi-ciliated epithelial cell differentiation	--
ENSG00000165338	3.969	1.867	1.447	1.732	1.805	2.546	246	165	93	115	127	115	HECTD2	HECT domain E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:26736]	-	-	-	-	GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity	GO:0016567//protein ubiquitination	--
ENSG00000165349	0.151	0.021	0.117	0.204	0.026	0.089	7	1	4	7	1	3	SLC7A3	solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000064//L-ornithine transmembrane transporter activity;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015189//L-lysine transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0061459//L-arginine transmembrane transporter activity	GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:0097638//L-arginine import across plasma membrane;GO:0097639//L-lysine import across plasma membrane;GO:0097640//L-ornithine import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903352//L-ornithine transmembrane transport;GO:1903826//arginine transmembrane transport	--
ENSG00000165355	7.238	6.732	7.689	6.61	6.159	7.998	550	512	429	383	407	424	FBXO33	F-box protein 33 [Source:HGNC Symbol;Acc:HGNC:19833]	-	-	-	-	GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination	--
ENSG00000165359	1.791	1.263	1.287	1.434	2.201	1.467	145	102	77	86	150	84	INTS6L	integrator complex subunit 6 like [Source:HGNC Symbol;Acc:HGNC:27334]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000165370	0	0	0	0	0	0.008	0	0	0	0	0	1	GPR101	G protein-coupled receptor 101 [Source:HGNC Symbol;Acc:HGNC:14963]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway	--
ENSG00000165376	1.971	1.96	2.668	4.572	4.433	6.054	121	121	121	208	230	270	CLDN2	claudin 2 [Source:HGNC Symbol;Acc:HGNC:2041]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly;GO:0098609//cell-cell adhesion	--
ENSG00000165379	0.643	0.662	0.591	0.501	0.626	0.465	54	61	40	34	48	31	LRFN5	leucine rich repeat and fibronectin type III domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20360]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0043031//negative regulation of macrophage activation;GO:0050728//negative regulation of inflammatory response;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000165383	0	0	0	0	0	0	0	0	0	0	0	0	LRRC18	leucine rich repeat containing 18 [Source:HGNC Symbol;Acc:HGNC:23199]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000165389	12.931	10.721	13.634	11.418	9.539	14.138	714	595	556	467	445	568	SPTSSA	serine palmitoyltransferase small subunit A [Source:HGNC Symbol;Acc:HGNC:20361]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex	GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0008104//protein localization;GO:0030148//sphingolipid biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000165392	2.272	2.855	2.882	1.256	1.734	1.223	280	217	138	125	161	116	WRN	WRN RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:12791]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016607//nuclear speck;GO:0043005//neuron projection"	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000400//four-way junction DNA binding;GO:0000403//Y-form DNA binding;GO:0000405//bubble DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0003824//catalytic activity;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008408//3'-5' exonuclease activity;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030145//manganese ion binding;GO:0032405//MutLalpha complex binding;GO:0042803//protein homodimerization activity;GO:0043138//3'-5' DNA helicase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051880//G-quadruplex DNA binding;GO:0061749//forked DNA-dependent helicase activity;GO:0061821//telomeric D-loop binding;GO:0061849//telomeric G-quadruplex DNA binding;GO:0070337//3'-flap-structured DNA binding;GO:1905773//8-hydroxy-2'-deoxyguanosine DNA binding	GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0000731//DNA synthesis involved in DNA repair;GO:0006139//nucleobase-containing compound metabolic process;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007420//brain development;GO:0007568//aging;GO:0007569//cell aging;GO:0008152//metabolic process;GO:0009267//cellular response to starvation;GO:0010225//response to UV-C;GO:0010259//multicellular organism aging;GO:0031297//replication fork processing;GO:0032201//telomere maintenance via semi-conservative replication;GO:0032508//DNA duplex unwinding;GO:0040009//regulation of growth rate;GO:0042981//regulation of apoptotic process;GO:0044237//cellular metabolic process;GO:0044806//G-quadruplex DNA unwinding;GO:0051345//positive regulation of hydrolase activity;GO:0061820//telomeric D-loop disassembly;GO:0071480//cellular response to gamma radiation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090399//replicative senescence;GO:0090656//t-circle formation;GO:0098530//positive regulation of strand invasion;GO:1902570//protein localization to nucleolus	--
ENSG00000165406	27.457	25.806	23.191	21.597	24.055	19.253	2051	2078	1482	1349	1695	1249	MARCHF8	membrane associated ring-CH-type finger 8 [Source:HGNC Symbol;Acc:HGNC:23356]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042287//MHC protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II;GO:0006955//immune response;GO:0016567//protein ubiquitination	--
ENSG00000165409	0	0	0	0	0	0	0	0	0	0	0	0	TSHR	thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune disease;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko05320//Autoimmune thyroid disease;ko04918//Thyroid hormone synthesis;ko04923//Regulation of lipolysis in adipocytes	K04249;K04249;K04249;K04249;K04249	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0004996//thyroid-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity;GO:0038023//signaling receptor activity;GO:0044877//protein-containing complex binding	"GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008344//adult locomotory behavior;GO:0009755//hormone-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0038194//thyroid-stimulating hormone signaling pathway;GO:0040012//regulation of locomotion;GO:0040018//positive regulation of multicellular organism growth;GO:0060119//inner ear receptor cell development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0071542//dopaminergic neuron differentiation;GO:0090103//cochlea morphogenesis;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1904588//cellular response to glycoprotein;GO:1905229//cellular response to thyrotropin-releasing hormone"	--
ENSG00000165410	47.218	37.93	40.296	42.814	40.375	40.406	1551	1416	1100	1026	1165	1036	CFL2	cofilin 2 [Source:HGNC Symbol;Acc:HGNC:1875]	Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cell motility;Infectious disease: viral;Development and regeneration;Immune system;Infectious disease: bacterial	ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis;ko05133//Pertussis	K05765;K05765;K05765;K05765;K05765	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016363//nuclear matrix;GO:0030018//Z disc;GO:0031674//I band;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007519//skeletal muscle tissue development;GO:0030042//actin filament depolymerization;GO:0030043//actin filament fragmentation;GO:0030836//positive regulation of actin filament depolymerization;GO:0045214//sarcomere organization;GO:0046716//muscle cell cellular homeostasis;GO:0048870//cell motility;GO:0051014//actin filament severing	--
ENSG00000165416	13.755	13.018	11.404	9.004	12.041	12.848	692	567	432	339	511	428	SUGT1	"SGT1 homolog, MIS12 kinetochore complex assembly cochaperone [Source:HGNC Symbol;Acc:HGNC:16987]"	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12795	GO:0000151//ubiquitin ligase complex;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0051087//chaperone binding	GO:0000278//mitotic cell cycle;GO:0031647//regulation of protein stability;GO:0050821//protein stabilization	--
ENSG00000165417	10.261	6.82	6.58	6.538	6.177	9.597	1003	706	630	550	591	556	GTF2A1	general transcription factor IIA subunit 1 [Source:HGNC Symbol;Acc:HGNC:4646]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors	K03122;K03122	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097550//transcription preinitiation complex	GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000165424	5.418	5.711	6.62	6.297	6.262	5.631	554	587	500	477	541	419	ZCCHC24	zinc finger CCHC-type containing 24 [Source:HGNC Symbol;Acc:HGNC:26911]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000165434	1.655	1.069	1.194	0.53	0.727	0.696	291	189	155	69	108	89	PGM2L1	phosphoglucomutase 2 like 1 [Source:HGNC Symbol;Acc:HGNC:20898]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism	K11809;K11809	GO:0005829//cytosol	"GO:0016740//transferase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding;GO:0047933//glucose-1,6-bisphosphate synthase activity"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0016310//phosphorylation;GO:0071704//organic substance metabolic process	--
ENSG00000165443	14.145	12.669	17.423	20.88	19.257	27.771	869.7	750.76	778.41	925.3	895.96	1141.29	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein like [Source:HGNC Symbol;Acc:HGNC:29378]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000165449	1.928	2.382	2.018	1.699	1.807	0.789	154	192	122	103	120	47	SLC16A9	solute carrier family 16 member 9 [Source:HGNC Symbol;Acc:HGNC:23520]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport	--
ENSG00000165457	0	0	0	0	0.163	0	0	0	0	0	2	0	FOLR2	folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793]	Cellular Processes;Human Diseases	Transport and catabolism;Drug resistance: antineoplastic	ko04144//Endocytosis;ko01523//Antifolate resistance	K13649;K13649	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane	GO:0005542//folic acid binding;GO:0038023//signaling receptor activity;GO:0061714//folic acid receptor activity	GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0008284//positive regulation of cell population proliferation;GO:0015884//folic acid transport;GO:0035036//sperm-egg recognition;GO:0071231//cellular response to folic acid;GO:1904447//folate import across plasma membrane	--
ENSG00000165458	35.147	36.03	40.835	40.533	48.371	42.778	3371	3355	2849	2772	3353	2913	INPPL1	inositol polyphosphate phosphatase like 1 [Source:HGNC Symbol;Acc:HGNC:6080]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Metabolism	Global and overview maps;Immune system;Immune system;Endocrine system;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04910//Insulin signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K15909;K15909;K15909;K15909;K15909;K15909	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0042995//cell projection	"GO:0003779//actin binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0042169//SH2 domain binding"	GO:0001958//endochondral ossification;GO:0002376//immune system process;GO:0006006//glucose metabolic process;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006897//endocytosis;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0009791//post-embryonic development;GO:0010629//negative regulation of gene expression;GO:0032868//response to insulin;GO:0044255//cellular lipid metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0097178//ruffle assembly	--
ENSG00000165462	0	0	0	0	0	0	0	0	0	0	0	0	PHOX2A	paired like homeobox 2A [Source:HGNC Symbol;Acc:HGNC:691]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0003357//noradrenergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021523//somatic motor neuron differentiation;GO:0021623//oculomotor nerve formation;GO:0021642//trochlear nerve formation;GO:0021703//locus ceruleus development;GO:0030901//midbrain development;GO:0043576//regulation of respiratory gaseous exchange;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048484//enteric nervous system development;GO:0048485//sympathetic nervous system development;GO:0048486//parasympathetic nervous system development;GO:0071542//dopaminergic neuron differentiation"	Homeobox
ENSG00000165471	0	0	0	0	0	0	0	0	0	0	0	0	MBL2	mannose binding lectin 2 [Source:HGNC Symbol;Acc:HGNC:6922]	Human Diseases;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: viral;Transport and catabolism;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko04145//Phagosome;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K03991;K03991;K03991;K03991	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0062023//collagen-containing extracellular matrix;GO:1905370//serine-type endopeptidase complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding	"GO:0001867//complement activation, lectin pathway;GO:0002376//immune system process;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0006953//acute-phase response;GO:0006958//complement activation, classical pathway;GO:0006979//response to oxidative stress;GO:0008228//opsonization;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0048525//negative regulation of viral process;GO:0050766//positive regulation of phagocytosis;GO:0050830//defense response to Gram-positive bacterium;GO:0051873//killing by host of symbiont cells;GO:1903028//positive regulation of opsonization"	--
ENSG00000165474	0.126	0.042	0.029	0.369	0.05	0.289	6	2	1	13	2	10	GJB2	gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284]	-	-	-	-	GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:0097449//astrocyte projection	GO:0005243//gap junction channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1903763//gap junction channel activity involved in cell communication by electrical coupling	GO:0002931//response to ischemia;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0007568//aging;GO:0007605//sensory perception of sound;GO:0010644//cell communication by electrical coupling;GO:0016264//gap junction assembly;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0032526//response to retinoic acid;GO:0032570//response to progesterone;GO:0034599//cellular response to oxidative stress;GO:0044752//response to human chorionic gonadotropin;GO:0046677//response to antibiotic;GO:0046697//decidualization;GO:0048839//inner ear development;GO:0055085//transmembrane transport;GO:0071377//cellular response to glucagon stimulus;GO:0071549//cellular response to dexamethasone stimulus;GO:1905867//epididymis development;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000165475	42.412	40.78	49.137	57.437	51.06	63.738	1290	1240	1100	1289	1311	1414	CRYL1	crystallin lambda 1 [Source:HGNC Symbol;Acc:HGNC:18246]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00040//Pentose and glucuronate interconversions	K13247;K13247	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042803//protein homodimerization activity;GO:0050104//L-gulonate 3-dehydrogenase activity;GO:0070403//NAD+ binding"	GO:0006631//fatty acid metabolic process	--
ENSG00000165476	27.844	21.2	24.182	15.504	17.984	20.895	2987	2286	1916	1232	1630	1631	REEP3	receptor accessory protein 3 [Source:HGNC Symbol;Acc:HGNC:23711]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0006998//nuclear envelope organization;GO:0007049//cell cycle;GO:0007084//mitotic nuclear membrane reassembly;GO:0051301//cell division;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000165478	0.073	0.165	0.033	0.081	0.229	0	4.9	11.1	1.62	4	12.95	0	HEPACAM	hepatic and glial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:26361]	-	-	-	-	GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	-	GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0034613//cellular protein localization;GO:0040008//regulation of growth	--
ENSG00000165480	0.456	0.274	0.443	0.219	0.322	0.652	18	16	12	4	16	14	SKA3	spindle and kinetochore associated complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20262]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0072686//mitotic spindle"	GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division	--
ENSG00000165487	21.206	18.929	17.795	16.599	13.956	19.906	729	669	497	442	461	526	MICU2	mitochondrial calcium uptake 2 [Source:HGNC Symbol;Acc:HGNC:31830]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0034704//calcium channel complex;GO:1990246//uniplex complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0036444//calcium import into the mitochondrion;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0051562//negative regulation of mitochondrial calcium ion concentration	--
ENSG00000165490	0.485	0.554	0.239	0.189	0.345	0.539	33	34	12	6	10	12	DDIAS	DNA damage induced apoptosis suppressor [Source:HGNC Symbol;Acc:HGNC:26351]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0097752//regulation of DNA stability;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	--
ENSG00000165494	5.571	6.399	4.709	3.811	5.565	5.359	542	492	313	233	373	314	PCF11	PCF11 cleavage and polyadenylation factor subunit [Source:HGNC Symbol;Acc:HGNC:30097]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14400	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005849//mRNA cleavage factor complex	GO:0000993//RNA polymerase II complex binding;GO:0003729//mRNA binding	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006379//mRNA cleavage;GO:0006397//mRNA processing	--
ENSG00000165495	31.97	32.405	31.814	20.62	24.751	22.455	2266	2366	1654	1124	1421	1148	PKNOX2	PBX/knotted 1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:16714]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0051015//actin filament binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000165496	0	0	0	0	0	0	0	0	0	0	0	0	RPL10L	ribosomal protein L10 like [Source:HGNC Symbol;Acc:HGNC:17976]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02866;K02866	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit	GO:0003735//structural constituent of ribosome	GO:0000027//ribosomal large subunit assembly;GO:0006412//translation;GO:0007283//spermatogenesis	--
ENSG00000165501	2.375	1.927	1.9	1.735	1.907	2.578	70	63	44	40	47	56	LRR1	leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0016567//protein ubiquitination	--
ENSG00000165502	45.929	51.583	47.799	48.911	48.37	39.207	644	727	495	508	573	400	RPL36AL	ribosomal protein L36a like [Source:HGNC Symbol;Acc:HGNC:10346]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02929;K02929	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0022625//cytosolic large ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation	--
ENSG00000165506	4.596	3.762	4.034	3.584	3.614	4.579	280	231	181	161	187	202	DNAAF2	dynein axonemal assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:20188]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101031//chaperone complex;GO:0120293//dynein axonemal particle	GO:0005515//protein binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0050821//protein stabilization;GO:0060285//cilium-dependent cell motility;GO:0070286//axonemal dynein complex assembly	--
ENSG00000165507	4.002	4.299	5.265	4.206	4.309	4.622	176	190	171	137	144	134	DEPP1	DEPP1 autophagy regulator [Source:HGNC Symbol;Acc:HGNC:23355]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0043231//intracellular membrane-bounded organelle	-	GO:0006914//autophagy;GO:0010506//regulation of autophagy	--
ENSG00000165509	0	0	0	0	0	0	0	0	0	0	0	0	MAGEC3	MAGE family member C3 [Source:HGNC Symbol;Acc:HGNC:23798]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000165512	13.755	12.681	14.62	11.235	11.261	15.754	600	556	471	363	415	500	ZNF22	zinc finger protein 22 [Source:HGNC Symbol;Acc:HGNC:13012]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0042476//odontogenesis"	zf-C2H2
ENSG00000165516	28.786	26.382	23.753	22.292	20.133	24.372	1055.77	987.18	633.51	602.7	651.03	639.8	KLHDC2	kelch domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20231]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000165521	1.373	0.718	1.027	0.689	0.985	0.77	107.49	114.21	76.94	68.14	88.58	70.62	EML5	EMAP like 5 [Source:HGNC Symbol;Acc:HGNC:18197]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0008150//biological_process	--
ENSG00000165525	5.716	3.945	2.715	2.214	4.898	5.859	450.23	304.82	214.49	159.3	268.97	216.2	NEMF	nuclear export mediator factor [Source:HGNC Symbol;Acc:HGNC:10663]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:1990112//RQC complex	GO:0000049//tRNA binding;GO:0043023//ribosomal large subunit binding	GO:0034622//cellular protein-containing complex assembly;GO:0051168//nuclear export;GO:0072344//rescue of stalled ribosome;GO:1990116//ribosome-associated ubiquitin-dependent protein catabolic process	--
ENSG00000165526	8.217	7.405	10.079	9.197	7.954	9.792	392	381	291	306	344	297	RPUSD4	RNA pseudouridine synthase D4 [Source:HGNC Symbol;Acc:HGNC:25898]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:1990400//mitochondrial ribosomal large subunit rRNA binding	GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0070131//positive regulation of mitochondrial translation;GO:0070902//mitochondrial tRNA pseudouridine synthesis	--
ENSG00000165527	15.111	13.254	13.891	11.608	11.874	12.281	1219	1073	825	694	808	719	ARF6	ADP ribosylation factor 6 [Source:HGNC Symbol;Acc:HGNC:659]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Signal transduction;Infectious disease: bacterial;Immune system	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko05135//Yersinia infection;ko04666//Fc gamma R-mediated phagocytosis	K07941;K07941;K07941;K07941;K07941;K07941;K07941;K07941	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0031527//filopodium membrane;GO:0031901//early endosome membrane;GO:0032154//cleavage furrow;GO:0042995//cell projection;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0090543//Flemming body;GO:0098793//presynapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0031996//thioesterase binding;GO:0047485//protein N-terminus binding	GO:0001889//liver development;GO:0006886//intracellular protein transport;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0010975//regulation of neuron projection development;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0030838//positive regulation of actin filament polymerization;GO:0030866//cortical actin cytoskeleton organization;GO:0032456//endocytic recycling;GO:0033028//myeloid cell apoptotic process;GO:0034394//protein localization to cell surface;GO:0035020//regulation of Rac protein signal transduction;GO:0036010//protein localization to endosome;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0050714//positive regulation of protein secretion;GO:0051301//cell division;GO:0051489//regulation of filopodium assembly;GO:0051549//positive regulation of keratinocyte migration;GO:0060998//regulation of dendritic spine development;GO:0090162//establishment of epithelial cell polarity;GO:0097178//ruffle assembly;GO:0097284//hepatocyte apoptotic process;GO:0099562//maintenance of postsynaptic density structure;GO:0120183//positive regulation of focal adhesion disassembly;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1905606//regulation of presynapse assembly;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000009//negative regulation of protein localization to cell surface;GO:2000171//negative regulation of dendrite development	--
ENSG00000165533	17.967	15.46	15.689	12.736	15.408	16.167	538	475	364	306	397	362	TTC8	tetratricopeptide repeat domain 8 [Source:HGNC Symbol;Acc:HGNC:20087]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0032391//photoreceptor connecting cilium;GO:0034464//BBSome;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001736//establishment of planar polarity;GO:0007411//axon guidance;GO:0007608//sensory perception of smell;GO:0015031//protein transport;GO:0021772//olfactory bulb development;GO:0030030//cell projection organization;GO:0032880//regulation of protein localization;GO:0034260//negative regulation of GTPase activity;GO:0035264//multicellular organism growth;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045444//fat cell differentiation;GO:0048560//establishment of anatomical structure orientation;GO:0050893//sensory processing;GO:0051492//regulation of stress fiber assembly;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0060271//cilium assembly;GO:0061326//renal tubule development;GO:0072659//protein localization to plasma membrane;GO:1903251//multi-ciliated epithelial cell differentiation;GO:1905515//non-motile cilium assembly	--
ENSG00000165548	5.947	7.104	6.808	6.547	5.708	6.026	579	652	532	474	503	462	TMEM63C	transmembrane protein 63C [Source:HGNC Symbol;Acc:HGNC:23787]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005227//calcium activated cation channel activity;GO:1990760//osmolarity-sensing cation channel activity	GO:0003094//glomerular filtration;GO:0006811//ion transport;GO:0006812//cation transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000165553	0	0	0	0	0	0	0	0	0	0	0	0	NGB	neuroglobin [Source:HGNC Symbol;Acc:HGNC:14077]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043204//perikaryon	GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0015671//oxygen transport	--
ENSG00000165555	0.188	0.206	0.253	0.084	0.097	0.114	9	10	9	3	3	4	NOXRED1	NADP dependent oxidoreductase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20487]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0004735//pyrroline-5-carboxylate reductase activity;GO:0016491//oxidoreductase activity	GO:0006561//proline biosynthetic process;GO:0008150//biological_process;GO:0055129//L-proline biosynthetic process	--
ENSG00000165556	0	0	0	0	0	0	0	0	0	0	0	0	CDX2	caudal type homeobox 2 [Source:HGNC Symbol;Acc:HGNC:1806]	Human Diseases	Cancer: specific types	ko05226//Gastric cancer	K22234	GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0001824//blastocyst development;GO:0001829//trophectodermal cell differentiation;GO:0001890//placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007389//pattern specification process;GO:0008284//positive regulation of cell population proliferation;GO:0008333//endosome to lysosome transport;GO:0009887//animal organ morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0014807//regulation of somitogenesis;GO:0030154//cell differentiation;GO:0035019//somatic stem cell population maintenance;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045597//positive regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060575//intestinal epithelial cell differentiation;GO:0060711//labyrinthine layer development"	Homeobox
ENSG00000165566	0.367	0.285	0.249	0.181	0.1	0.129	79	62	40	28	18	20	AMER2	APC membrane recruitment protein 2 [Source:HGNC Symbol;Acc:HGNC:26360]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008013//beta-catenin binding;GO:0008289//lipid binding"	GO:0007398//ectoderm development;GO:0016055//Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000165568	0.087	0.094	0.252	0.323	0.035	0	2	3	4	5	1	0	AKR1E2	aldo-keto reductase family 1 member E2 [Source:HGNC Symbol;Acc:HGNC:23437]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0016491//oxidoreductase activity;GO:0050571//1,5-anhydro-D-fructose reductase activity"	-	--
ENSG00000165572	6.075	5.639	5.574	5.477	5.244	5.449	659.49	615.32	446.91	440.46	481	430.44	KBTBD6	kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006986//response to unfolded protein;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0035020//regulation of Rac protein signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000165583	0	0	0	0	0.044	0	0	0	0	0	1	0	SSX5	SSX family member 5 [Source:HGNC Symbol;Acc:HGNC:11339]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000165584	0	0	0	0	0	0	0	0	0	0	0	0	SSX3	SSX family member 3 [Source:HGNC Symbol;Acc:HGNC:11337]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000165588	255.112	240.567	242.793	209.617	221.041	258.573	10342	9821	7531	6321	7483	7735	OTX2	orthodenticle homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8522]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0030426//growth cone;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007411//axon guidance;GO:0008589//regulation of smoothened signaling pathway;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0040019//positive regulation of embryonic development;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0065003//protein-containing complex assembly;GO:0071542//dopaminergic neuron differentiation;GO:0090009//primitive streak formation;GO:2000543//positive regulation of gastrulation"	TF_Otx
ENSG00000165591	1.364	1.332	1.484	1.183	1.21	1.372	56	55	45	36	42	41	FAAH2	fatty acid amide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:26440]	-	-	-	-	GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0017064//fatty acid amide hydrolase activity;GO:0102077//oleamide hydrolase activity;GO:0103073//anandamide amidohydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process	--
ENSG00000165606	0.047	0.016	0	0	0.019	0.022	3	1	0	0	1	1	DRGX	dorsal root ganglia homeobox [Source:HGNC Symbol;Acc:HGNC:21536]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0009593//detection of chemical stimulus;GO:0016048//detection of temperature stimulus;GO:0021516//dorsal spinal cord development;GO:0021559//trigeminal nerve development;GO:0030182//neuron differentiation;GO:0050954//sensory perception of mechanical stimulus"	Homeobox
ENSG00000165609	25.233	27.491	24.443	23.092	26.796	30.287	1006	970	718	684	863	933	NUDT5	nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13987;K13987	GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0030515//snoRNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044715//8-oxo-dGDP phosphatase activity;GO:0044716//8-oxo-GDP phosphatase activity;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006338//chromatin remodeling;GO:0006753//nucleoside phosphate metabolic process;GO:0009117//nucleotide metabolic process;GO:0009191//ribonucleoside diphosphate catabolic process;GO:0019303//D-ribose catabolic process;GO:0019693//ribose phosphate metabolic process;GO:0055086//nucleobase-containing small molecule metabolic process;GO:1990966//ATP generation from poly-ADP-D-ribose	--
ENSG00000165617	3.842	4.876	3.307	1.632	2.135	2.433	242	306	116	74	127	80	DACT1	dishevelled binding antagonist of beta catenin 1 [Source:HGNC Symbol;Acc:HGNC:17748]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0030877//beta-catenin destruction complex;GO:0045202//synapse	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0042826//histone deacetylase binding;GO:0051018//protein kinase A binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070097//delta-catenin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009968//negative regulation of signal transduction;GO:0016055//Wnt signaling pathway;GO:0021915//neural tube development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0045732//positive regulation of protein catabolic process;GO:0046329//negative regulation of JNK cascade;GO:0048619//embryonic hindgut morphogenesis;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1903364//positive regulation of cellular protein catabolic process;GO:1904864//negative regulation of beta-catenin-TCF complex assembly;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000165621	0	0.021	0	0	0.023	0.029	0	1	0	0	1	1	OXGR1	oxoglutarate receptor 1 [Source:HGNC Symbol;Acc:HGNC:4531]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000165623	0	0	0	0	0	0	0	0	0	0	0	0	UCMA	upper zone of growth plate and cartilage matrix associated [Source:HGNC Symbol;Acc:HGNC:25205]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031012//extracellular matrix	GO:0036122//BMP binding	GO:0045667//regulation of osteoblast differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0048706//embryonic skeletal system development;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0110150//negative regulation of biomineralization	--
ENSG00000165626	7.612	5.826	7.338	5.372	6.879	6.074	549	407.09	351	263	385	309	BEND7	BEN domain containing 7 [Source:HGNC Symbol;Acc:HGNC:23514]	-	-	-	-	GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000165629	83.543	84.211	80.845	86.782	73.51	72.378	1906	1929	1363	1465	1417	1202	ATP5F1C	ATP synthase F1 subunit gamma [Source:HGNC Symbol;Acc:HGNC:833]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02136;K02136;K02136;K02136;K02136;K02136;K02136;K02136;K02136;K02136;K02136	"GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)"	"GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006119//oxidative phosphorylation;GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000165630	6.707	6.048	4.976	5.357	4.884	5.765	224.85	209.14	127.29	137.45	141.6	145.29	PRPF18	pre-mRNA processing factor 18 [Source:HGNC Symbol;Acc:HGNC:17351]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12817	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071021//U2-type post-spliceosomal complex;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0071028//nuclear mRNA surveillance	--
ENSG00000165632	2.354	1.882	1.567	1.243	1.393	1.658	238	191	117	93	119	122	TAF3	TATA-box binding protein associated factor 3 [Source:HGNC Symbol;Acc:HGNC:17303]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K14650	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0031965//nuclear membrane	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0140416//transcription regulator inhibitor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0051457//maintenance of protein location in nucleus;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter	--
ENSG00000165633	1.638	1.892	1.537	1.904	1.379	1.56	213	253	151	182	155	151	VSTM4	V-set and transmembrane domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26470]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001935//endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0042311//vasodilation;GO:0043542//endothelial cell migration;GO:0061298//retina vasculature development in camera-type eye;GO:0097601//retina blood vessel maintenance	--
ENSG00000165637	81.098	78.512	80.497	84.367	78.554	84.59	2230	2270	1741	1728	2002	1818	VDAC2	voltage dependent anion channel 2 [Source:HGNC Symbol;Acc:HGNC:12672]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Immune system;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease;Digestive system;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko04621//NOD-like receptor signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia;ko04979//Cholesterol metabolism;ko04216//Ferroptosis	K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040;K15040	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0042645//mitochondrial nucleoid;GO:0046930//pore complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008308//voltage-gated anion channel activity;GO:0015288//porin activity;GO:0015485//cholesterol binding;GO:0031210//phosphatidylcholine binding;GO:0097001//ceramide binding	GO:0006811//ion transport;GO:0006820//anion transport;GO:0007339//binding of sperm to zona pellucida;GO:0015698//inorganic anion transport;GO:0032272//negative regulation of protein polymerization;GO:0055085//transmembrane transport;GO:0097345//mitochondrial outer membrane permeabilization;GO:0098656//anion transmembrane transport;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000165643	0	0	0	0	0	0	0	0	0	0	0	0	SOHLH1	spermatogenesis and oogenesis specific basic helix-loop-helix 1 [Source:HGNC Symbol;Acc:HGNC:27845]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0009994//oocyte differentiation;GO:0030154//cell differentiation;GO:0048477//oogenesis"	bHLH
ENSG00000165644	5.972	7.367	8.408	8.279	10.042	11.179	151	192	161	159	209	203	COMTD1	catechol-O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26309]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000165646	0	0	0	0	0.038	0	0	0	0	0	2.54	0	SLC18A2	solute carrier family 18 member A2 [Source:HGNC Symbol;Acc:HGNC:10935]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Substance dependence;Nervous system;Nervous system;Nervous system;Substance dependence;Substance dependence	ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko04721//Synaptic vesicle cycle;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K08155;K08155;K08155;K08155;K08155;K08155;K08155	GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043195//terminal bouton;GO:0043231//intracellular membrane-bounded organelle;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0098691//dopaminergic synapse	GO:0005335//serotonin:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0001975//response to amphetamine;GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0007626//locomotory behavior;GO:0009636//response to toxic substance;GO:0009791//post-embryonic development;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0015844//monoamine transport;GO:0015872//dopamine transport;GO:0042137//sequestering of neurotransmitter;GO:0051610//serotonin uptake;GO:0055085//transmembrane transport;GO:0098700//neurotransmitter loading into synaptic vesicle;GO:1903427//negative regulation of reactive oxygen species biosynthetic process	--
ENSG00000165650	7.931	5.782	5.345	3.647	4.251	4.98	1591	1166	792	542	720.46	727	PDZD8	PDZ domain containing 8 [Source:HGNC Symbol;Acc:HGNC:26974]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0046872//metal ion binding	GO:0006869//lipid transport;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0051560//mitochondrial calcium ion homeostasis;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000165655	23.496	21.805	22.934	23.049	25.158	26.422	1562	1457	1126	1135	1413	1278	ZNF503	zinc finger protein 503 [Source:HGNC Symbol;Acc:HGNC:23589]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0061351//neural precursor cell proliferation;GO:0070315//G1 to G0 transition involved in cell differentiation"	Others
ENSG00000165660	5.678	5.681	4.065	4.119	4.21	5.225	348	350	184	187	218	233	ABRAXAS2	"abraxas 2, BRISC complex subunit [Source:HGNC Symbol;Acc:HGNC:28975]"	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030496//midbody;GO:0031616//spindle pole centrosome;GO:0036449//microtubule minus-end;GO:0070552//BRISC complex	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0000278//mitotic cell cycle;GO:0002931//response to ischemia;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051301//cell division;GO:0070536//protein K63-linked deubiquitination;GO:0090307//mitotic spindle assembly	--
ENSG00000165661	4.002	3.718	3.8	3.445	3.727	4.21	313	282	262	232	294	286	QSOX2	quiescin sulfhydryl oxidase 2 [Source:HGNC Symbol;Acc:HGNC:30249]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031965//nuclear membrane	GO:0003756//protein disulfide isomerase activity;GO:0016491//oxidoreductase activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0016972//thiol oxidase activity	GO:0006457//protein folding	--
ENSG00000165669	14.819	13.648	12.782	10.567	10.716	11.894	472	428	355	223	260	270	FAM204A	family with sequence similarity 204 member A [Source:HGNC Symbol;Acc:HGNC:25794]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000165671	16.101	12.016	13.301	10.626	13.927	12.924	3035	2601	1916	1596	2209	1805	NSD1	nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K15588;K15588	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0030331//estrogen receptor binding;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0042974//retinoic acid receptor binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0050681//androgen receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000414//regulation of histone H3-K36 methylation;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0010452//histone H3-K36 methylation;GO:0016571//histone methylation;GO:0032259//methylation;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0034770//histone H4-K20 methylation;GO:0034968//histone lysine methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1903025//regulation of RNA polymerase II regulatory region sequence-specific DNA binding"	--
ENSG00000165672	94.902	92.285	98.315	99.704	86.681	103.508	3057	2988	2339	2379	2359	2426	PRDX3	peroxiredoxin 3 [Source:HGNC Symbol;Acc:HGNC:9354]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008379//thioredoxin peroxidase activity;GO:0008785//alkyl hydroperoxide reductase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0051920//peroxiredoxin activity	GO:0001893//maternal placenta development;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0008284//positive regulation of cell population proliferation;GO:0018171//peptidyl-cysteine oxidation;GO:0030099//myeloid cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0033673//negative regulation of kinase activity;GO:0034599//cellular response to oxidative stress;GO:0034614//cellular response to reactive oxygen species;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045454//cell redox homeostasis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051881//regulation of mitochondrial membrane potential;GO:0098869//cellular oxidant detoxification	--
ENSG00000165675	5.439	4.006	3.914	3.726	3.655	4.755	320	241	174	195	186	201	ENOX2	ecto-NOX disulfide-thiol exchanger 2 [Source:HGNC Symbol;Acc:HGNC:2259]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016491//oxidoreductase activity	GO:0007624//ultradian rhythm;GO:0022900//electron transport chain;GO:0040008//regulation of growth;GO:0048511//rhythmic process	--
ENSG00000165678	58.161	58.72	60.874	61.593	58.992	65.293	2909	2940	2244	2280	2482	2368	GHITM	growth hormone inducible transmembrane protein [Source:HGNC Symbol;Acc:HGNC:17281]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007007//inner mitochondrial membrane organization;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:1905448//positive regulation of mitochondrial ATP synthesis coupled electron transport	--
ENSG00000165682	0	0	0	0	0	0	0	0	0	0	0	0	CLEC1B	C-type lectin domain family 1 member B [Source:HGNC Symbol;Acc:HGNC:24356]	Organismal Systems	Immune system	ko04625//C-type lectin receptor signaling pathway	K10070	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0006952//defense response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030220//platelet formation	--
ENSG00000165684	2.269	2.757	2.418	2.814	3.16	2.514	221	270	174	203	260	178	SNAPC4	small nuclear RNA activating complex polypeptide 4 [Source:HGNC Symbol;Acc:HGNC:11137]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0019185//snRNA-activating protein complex	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0003677//DNA binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III	MYB
ENSG00000165685	0	0	0.025	0	0	0	0	0	1	0	0	0	TMEM52B	transmembrane protein 52B [Source:HGNC Symbol;Acc:HGNC:26438]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000165688	20.304	19.346	20.977	22.534	23.226	21.251	879	842	671	723	850	670	PMPCA	"peptidase, mitochondrial processing subunit alpha [Source:HGNC Symbol;Acc:HGNC:18667]"	-	-	-	-	GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0017087//mitochondrial processing peptidase complex	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006627//protein processing involved in protein targeting to mitochondrion	--
ENSG00000165689	13.072	13.902	17.822	15.088	15.963	18.659	571	571	468	439	509	537	ENTR1	endosome associated trafficking regulator 1 [Source:HGNC Symbol;Acc:HGNC:10667]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0030904//retromer complex;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0032456//endocytic recycling;GO:0032465//regulation of cytokinesis;GO:0045724//positive regulation of cilium assembly;GO:0051301//cell division;GO:1903566//positive regulation of protein localization to cilium	--
ENSG00000165694	0	0	0.041	0	0.054	0.032	0	0	2	0	2	1	FRMD7	FERM domain containing 7 [Source:HGNC Symbol;Acc:HGNC:8079]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0003674//molecular_function;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0010592//positive regulation of lamellipodium assembly;GO:0010975//regulation of neuron projection development;GO:0032091//negative regulation of protein binding;GO:0050790//regulation of catalytic activity;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0051497//negative regulation of stress fiber assembly	--
ENSG00000165695	1.71	2.673	2.067	1.525	1.662	1.217	56	88	50	37	46	29	AK8	adenylate kinase 8 [Source:HGNC Symbol;Acc:HGNC:26526]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005930//axoneme;GO:0036126//sperm flagellum;GO:0097729//9+2 motile cilium	GO:0000166//nucleotide binding;GO:0004017//adenylate kinase activity;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019205//nucleobase-containing compound kinase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0021591//ventricular system development;GO:0046940//nucleoside monophosphate phosphorylation	--
ENSG00000165698	4.53	5.79	6.794	3.939	4.782	3.11	210	252	200	134	190	111	SPACA9	sperm acrosome associated 9 [Source:HGNC Symbol;Acc:HGNC:1367]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000165699	8.338	8.009	9.185	6.225	7.794	7.327	1117	1066	854	653	846	775	TSC1	TSC complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:12362]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Environmental adaptation;Infectious disease: viral;Signal transduction;Signal transduction;Cell growth and death;Transport and catabolism;Endocrine system;Signal transduction;Cancer: overview;Aging	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko05231//Choline metabolism in cancer;ko04211//Longevity regulating pathway	K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206;K07206	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0032991//protein-containing complex;GO:0033596//TSC1-TSC2 complex;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0032794//GTPase activating protein binding;GO:0042030//ATPase inhibitor activity;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding	GO:0001822//kidney development;GO:0001843//neural tube closure;GO:0001952//regulation of cell-matrix adhesion;GO:0002250//adaptive immune response;GO:0006407//rRNA export from nucleus;GO:0006417//regulation of translation;GO:0006813//potassium ion transport;GO:0007160//cell-matrix adhesion;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0008306//associative learning;GO:0008344//adult locomotory behavior;GO:0010977//negative regulation of neuron projection development;GO:0016239//positive regulation of macroautophagy;GO:0016242//negative regulation of macroautophagy;GO:0017148//negative regulation of translation;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030030//cell projection organization;GO:0031667//response to nutrient levels;GO:0032007//negative regulation of TOR signaling;GO:0032780//negative regulation of ATPase activity;GO:0032868//response to insulin;GO:0034260//negative regulation of GTPase activity;GO:0042552//myelination;GO:0043379//memory T cell differentiation;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0045792//negative regulation of cell size;GO:0045859//regulation of protein kinase activity;GO:0046323//glucose import;GO:0050808//synapse organization;GO:0050821//protein stabilization;GO:0051492//regulation of stress fiber assembly;GO:0051496//positive regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0051893//regulation of focal adhesion assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0055007//cardiac muscle cell differentiation;GO:0090630//activation of GTPase activity;GO:0090650//cellular response to oxygen-glucose deprivation;GO:1901214//regulation of neuron death;GO:1901652//response to peptide;GO:1903204//negative regulation of oxidative stress-induced neuron death	--
ENSG00000165702	0	0	0	0	0	0	0	0	0	0	0	0	GFI1B	growth factor independent 1B transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4238]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005886//plasma membrane;GO:0016363//nuclear matrix	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903706//regulation of hemopoiesis;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	zf-C2H2
ENSG00000165704	7.43	9.284	10.014	11.198	8.059	9.025	215	270	214	240	197	190	HPRT1	hypoxanthine phosphoribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5157]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes	K00760;K00760;K00760	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004422//hypoxanthine phosphoribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0052657//guanine phosphoribosyltransferase activity	GO:0001913//T cell mediated cytotoxicity;GO:0001975//response to amphetamine;GO:0006164//purine nucleotide biosynthetic process;GO:0006166//purine ribonucleoside salvage;GO:0006178//guanine salvage;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0021756//striatum development;GO:0021895//cerebral cortex neuron differentiation;GO:0021954//central nervous system neuron development;GO:0032263//GMP salvage;GO:0032264//IMP salvage;GO:0042417//dopamine metabolic process;GO:0043103//hypoxanthine salvage;GO:0044209//AMP salvage;GO:0045964//positive regulation of dopamine metabolic process;GO:0046038//GMP catabolic process;GO:0046040//IMP metabolic process;GO:0046083//adenine metabolic process;GO:0046100//hypoxanthine metabolic process;GO:0046651//lymphocyte proliferation;GO:0048813//dendrite morphogenesis;GO:0051289//protein homotetramerization	--
ENSG00000165714	9.281	8.053	6.751	7.031	7.045	8.538	393	405	312	236	308	245	BORCS5	BLOC-1 related complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:17950]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005873//plus-end kinesin complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex	GO:0005515//protein binding	GO:0032418//lysosome localization;GO:0051036//regulation of endosome size;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule;GO:1903744//positive regulation of anterograde synaptic vesicle transport	--
ENSG00000165716	13.318	12.526	11.816	13.533	12.159	13.379	653	617	428	491	503	477	DIPK1B	divergent protein kinase domain 1B [Source:HGNC Symbol;Acc:HGNC:28290]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000165724	8.744	8.837	8.984	10.684	8.795	9.31	253	257	192	229	215	196	ZMYND19	zinc finger MYND-type containing 19 [Source:HGNC Symbol;Acc:HGNC:21146]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000165730	5.638	4.901	5.379	3.959	4.448	5.617	354	289	234	188	228	239	STOX1	storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005938//cell cortex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010821//regulation of mitochondrion organization;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045787//positive regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:0051301//cell division;GO:0051881//regulation of mitochondrial membrane potential;GO:0051897//positive regulation of protein kinase B signaling;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071500//cellular response to nitrosative stress;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1901858//regulation of mitochondrial DNA metabolic process;GO:1902882//regulation of response to oxidative stress;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:1904120//positive regulation of otic vesicle morphogenesis	--
ENSG00000165731	0.307	0.16	0.207	0.726	0.272	0.183	19	12	13	19	15	12	RET	ret proto-oncogene [Source:HGNC Symbol;Acc:HGNC:9967]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05216//Thyroid cancer	K05126;K05126;K05126;K05126;K05126	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0098797//plasma membrane protein complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038023//signaling receptor activity	"GO:0000165//MAPK cascade;GO:0001657//ureteric bud development;GO:0001755//neural crest cell migration;GO:0001838//embryonic epithelial tube formation;GO:0006468//protein phosphorylation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007158//neuron cell-cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007497//posterior midgut development;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0014042//positive regulation of neuron maturation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030155//regulation of cell adhesion;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0033619//membrane protein proteolysis;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0033674//positive regulation of kinase activity;GO:0035799//ureter maturation;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0042551//neuron maturation;GO:0043410//positive regulation of MAPK cascade;GO:0045793//positive regulation of cell size;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048265//response to pain;GO:0048484//enteric nervous system development;GO:0050770//regulation of axonogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0060041//retina development in camera-type eye;GO:0060384//innervation;GO:0061146//Peyer's patch morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0072300//positive regulation of metanephric glomerulus development;GO:0097021//lymphocyte migration into lymphoid organs;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000165732	11.468	11.003	9.419	5.833	7.794	9.889	1107	1057	673	418	637	684	DDX21	DExD-box helicase 21 [Source:HGNC Symbol;Acc:HGNC:2744]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0110016//B-WICH complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019843//rRNA binding;GO:0030515//snoRNA binding;GO:0035198//miRNA binding;GO:0042802//identical protein binding;GO:0097322//7SK snRNA binding	GO:0001649//osteoblast differentiation;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0006338//chromatin remodeling;GO:0006364//rRNA processing;GO:0006366//transcription by RNA polymerase II;GO:0009615//response to virus;GO:0035066//positive regulation of histone acetylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0045087//innate immune response;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0051607//defense response to virus;GO:0062176//R-loop disassembly	--
ENSG00000165733	5.543	4.89	4.56	3.255	3.479	4.108	892	791	542	388	473	481	BMS1	BMS1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:23505]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14569	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030686//90S preribosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0034511//U3 snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000479//endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042254//ribosome biogenesis"	--
ENSG00000165752	2.02	2.351	2.723	3.293	1.952	3.08	77	82	76	78	66	67	STK32C	serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000165757	15.926	14.81	14.842	10.708	12.283	12.138	3080	2879	2120	1534	2007	1708	JCAD	junctional cadherin 5 associated [Source:HGNC Symbol;Acc:HGNC:29283]	-	-	-	-	GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0048471//perinuclear region of cytoplasm	-	GO:0007155//cell adhesion;GO:0043410//positive regulation of MAPK cascade;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1903672//positive regulation of sprouting angiogenesis	--
ENSG00000165762	0	0	0	0	0	0	0	0	0	0	0	0	OR4K2	olfactory receptor family 4 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:14728]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000165775	29.389	28.181	29.483	27.393	26.824	24.573	984	959	665	663	744	613	FUNDC2	FUN14 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24925]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	"GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding"	GO:0000422//autophagy of mitochondrion;GO:0010543//regulation of platelet activation;GO:0035356//cellular triglyceride homeostasis	--
ENSG00000165782	11.343	15.348	11.552	14.692	11.956	13.221	411	461	303	396	369	347	PIP4P1	"phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:19299]"	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K13084	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity"	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006991//response to sterol depletion;GO:0008203//cholesterol metabolic process;GO:0032418//lysosome localization;GO:0046856//phosphatidylinositol dephosphorylation;GO:0070070//proton-transporting V-type ATPase complex assembly;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000165792	9.835	10.45	9.885	9.24	10.893	13.502	322	351	250	232	318	338	METTL17	methyltransferase like 17 [Source:HGNC Symbol;Acc:HGNC:19280]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:1904047//S-adenosyl-L-methionine binding	GO:0006412//translation;GO:0032259//methylation;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000165794	0	0	0	0	0	0	0	0	0	0	0	0	SLC39A2	solute carrier family 39 member 2 [Source:HGNC Symbol;Acc:HGNC:17127]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14709;K14709	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport	--
ENSG00000165795	28.931	31.745	33.27	31.127	29.54	33.5	796	902	690	637	734	680	NDRG2	NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:14460]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001818//negative regulation of cytokine production;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010574//regulation of vascular endothelial growth factor production;GO:0016055//Wnt signaling pathway;GO:0021762//substantia nigra development;GO:0030154//cell differentiation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090361//regulation of platelet-derived growth factor production	--
ENSG00000165799	0	0	0	0	0	0	0	0	0	0	0	0	RNASE7	ribonuclease A family member 7 [Source:HGNC Symbol;Acc:HGNC:19278]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0001530//lipopolysaccharide binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity;GO:0042834//peptidoglycan binding	GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051673//membrane disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000165801	15.078	18.438	17.568	15.851	16.065	16.926	1456.59	1712	1272	1174	1328	1137	ARHGEF40	Rho guanine nucleotide exchange factor 40 [Source:HGNC Symbol;Acc:HGNC:25516]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000165802	37.26	37.357	36.844	44.298	41.643	45.446	2142	2124	1587	1914	2163	1950	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor [Source:HGNC Symbol;Acc:HGNC:29843]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030863//cortical cytoskeleton;GO:0031965//nuclear membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0097440//apical dendrite	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	GO:0035307//positive regulation of protein dephosphorylation;GO:0043523//regulation of neuron apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048814//regulation of dendrite morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0071257//cellular response to electrical stimulus;GO:0071371//cellular response to gonadotropin stimulus;GO:2001222//regulation of neuron migration;GO:2001224//positive regulation of neuron migration	--
ENSG00000165804	15.781	15.538	17.863	19.25	18.589	17.555	890.41	927.51	779.95	814	946	753.84	ZNF219	zinc finger protein 219 [Source:HGNC Symbol;Acc:HGNC:13011]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004969//histamine receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001505//regulation of neurotransmitter levels;GO:0006355//regulation of transcription, DNA-templated;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060174//limb bud formation"	zf-C2H2
ENSG00000165805	0	0	0	0	0	0	0	0	0	0	0	0	C12orf50	chromosome 12 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:26665]	-	-	-	-	-	GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0016973//poly(A)+ mRNA export from nucleus	--
ENSG00000165806	6.687	7.118	7.027	6.888	6.579	9.293	338	360	242	256	245	270	CASP7	caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cardiovascular disease;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Cell growth and death	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko04932//Non-alcoholic fatty liver disease;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05133//Pertussis;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K04397;K04397;K04397;K04397;K04397;K04397;K04397;K04397;K04397;K04397;K04397;K04397	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004190//aspartic-type endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis	GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007507//heart development;GO:0009411//response to UV;GO:0016485//protein processing;GO:0051402//neuron apoptotic process;GO:0072734//cellular response to staurosporine;GO:0097194//execution phase of apoptosis	--
ENSG00000165807	0.107	0.249	0.145	0.096	0.212	0.147	3	7	3	2	5	3	PPP1R36	protein phosphatase 1 regulatory subunit 36 [Source:HGNC Symbol;Acc:HGNC:20097]	-	-	-	-	-	GO:0004864//protein phosphatase inhibitor activity;GO:0019902//phosphatase binding	GO:0010923//negative regulation of phosphatase activity	--
ENSG00000165810	0	0.042	0	0	0.033	0	0	3	0	0	2	0	BTNL9	butyrophilin like 9 [Source:HGNC Symbol;Acc:HGNC:24176]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0050852//T cell receptor signaling pathway	--
ENSG00000165813	3.262	2.021	1.842	1.454	1.818	1.994	422	242	182	104	221	190	CCDC186	coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network	GO:0031267//small GTPase binding	GO:0009617//response to bacterium;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0042593//glucose homeostasis;GO:0099518//vesicle cytoskeletal trafficking	--
ENSG00000165816	0.019	0	0.011	0.025	0.023	0	1	0	1	1	2	0	VWA2	von Willebrand factor A domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24709]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007161//calcium-independent cell-matrix adhesion;GO:0046626//regulation of insulin receptor signaling pathway	--
ENSG00000165819	10.646	12.593	12.831	10.266	11.171	12.5	436.56	520.63	390	315	389	374.76	METTL3	"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit [Source:HGNC Symbol;Acc:HGNC:17563]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0001734//mRNA (N6-adenosine)-methyltransferase activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016422//mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity;GO:0016740//transferase activity;GO:0046982//protein heterodimerization activity;GO:1904047//S-adenosyl-L-methionine binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0001510//RNA methylation;GO:0002376//immune system process;GO:0006382//adenosine to inosine editing;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0019827//stem cell population maintenance;GO:0021861//forebrain radial glial cell differentiation;GO:0030154//cell differentiation;GO:0031053//primary miRNA processing;GO:0032259//methylation;GO:0034644//cellular response to UV;GO:0042063//gliogenesis;GO:0045087//innate immune response;GO:0045580//regulation of T cell differentiation;GO:0045727//positive regulation of translation;GO:0045746//negative regulation of Notch signaling pathway;GO:0048477//oogenesis;GO:0048511//rhythmic process;GO:0051445//regulation of meiotic cell cycle;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061157//mRNA destabilization;GO:0080009//mRNA methylation;GO:0098508//endothelial to hematopoietic transition;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1903679//positive regulation of cap-independent translational initiation;GO:1990744//primary miRNA methylation"	--
ENSG00000165821	15.482	16.587	17.533	17.457	17.201	16.1	1538	1668	1289	1288	1434	1169	SALL2	spalt like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10526]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001654//eye development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0021915//neural tube development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000165828	22.648	20.009	19.976	17.587	16.513	17.821	338	302	222	192	203	194	PRAP1	proline rich acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:23304]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21250	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0017129//triglyceride binding	"GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0043066//negative regulation of apoptotic process;GO:0071481//cellular response to X-ray;GO:1902426//deactivation of mitotic spindle assembly checkpoint;GO:1904731//positive regulation of intestinal lipid absorption;GO:1905885//positive regulation of triglyceride transport;GO:2001140//positive regulation of phospholipid transport"	--
ENSG00000165832	10.517	8.9	8.548	8.561	8.997	9.805	743	632	446	448	537	504	TRUB1	TruB pseudouridine synthase family member 1 [Source:HGNC Symbol;Acc:HGNC:16060]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity	GO:0001522//pseudouridine synthesis;GO:0006396//RNA processing;GO:0006400//tRNA modification;GO:0009451//RNA modification;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000165837	0.04	0	0.081	0.027	0	0	2	0	3	1	0	0	ERICH6B	glutamate rich 6B [Source:HGNC Symbol;Acc:HGNC:26523]	-	-	-	-	-	-	-	--
ENSG00000165841	0	0	0	0	0	0	0	0	0	0	0	0	CYP2C19	cytochrome P450 family 2 subfamily C member 19 [Source:HGNC Symbol;Acc:HGNC:2621]	Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Nervous system;Cancer: overview;Xenobiotics biodegradation and metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism;ko00591//Linoleic acid metabolism	K17721;K17721;K17721;K17721;K17721;K17721	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0018675//(S)-limonene 6-monooxygenase activity;GO:0018676//(S)-limonene 7-monooxygenase activity;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0052741//(R)-limonene 6-monooxygenase activity;GO:0070330//aromatase activity;GO:0120319//long-chain fatty acid omega-1 hydroxylase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0016098//monoterpenoid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042178//xenobiotic catabolic process;GO:0046483//heterocycle metabolic process;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000165861	12.769	10.982	12.04	11.845	12.548	12.657	1159	1001	806	796	939	824	ZFYVE1	zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180]	Human Diseases;Cellular Processes	Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko04140//Autophagy - animal	K17603;K17603	GO:0000407//phagophore assembly site;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0097629//extrinsic component of omegasome membrane;GO:1990462//omegasome	"GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270//zinc ion binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding"	GO:0009267//cellular response to starvation;GO:0016236//macroautophagy;GO:0140042//lipid droplet formation	--
ENSG00000165863	0	0	0	0	0	0.206	0	0	0	0	0	3	C10orf82	chromosome 10 open reading frame 82 [Source:HGNC Symbol;Acc:HGNC:28500]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000165868	3.702	4.146	3.366	2.01	2.61	1.707	161	162	136	109	131	78.38	HSPA12A	heat shock protein family A (Hsp70) member 12A [Source:HGNC Symbol;Acc:HGNC:19022]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0008150//biological_process	--
ENSG00000165879	1.185	1.142	1.308	1.23	0.841	1.177	65	63	53	50	39	47	FRAT1	FRAT regulator of WNT signaling pathway 1 [Source:HGNC Symbol;Acc:HGNC:3944]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer	K03069;K03069;K03069;K03069;K03069;K03069;K03069	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0016055//Wnt signaling pathway;GO:0046825//regulation of protein export from nucleus;GO:0060070//canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904886//beta-catenin destruction complex disassembly	--
ENSG00000165886	25.32	22.424	25.921	35.764	27.891	37.696	865	770	654	905	805	937	UBTD1	ubiquitin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25683]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000165887	0	0.041	0.145	0.048	0.097	0.113	0	1	3	1	2	2	ANKRD2	ankyrin repeat domain 2 [Source:HGNC Symbol;Acc:HGNC:495]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0043422//protein kinase B binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045662//negative regulation of myoblast differentiation	--
ENSG00000165891	0.839	0.806	0.478	0.388	0.401	0.081	76	77	27	20	16	7	E2F7	E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0016607//nuclear speck;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001217//DNA-binding transcription repressor activity;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001890//placenta development;GO:0002040//sprouting angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032466//negative regulation of cytokinesis;GO:0032877//positive regulation of DNA endoreduplication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060707//trophoblast giant cell differentiation;GO:0060718//chorionic trophoblast cell differentiation;GO:0070365//hepatocyte differentiation;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	E2F
ENSG00000165895	7.254	6.844	4.461	5.1	6.476	5.098	840	723	506	382	529	487	ARHGAP42	Rho GTPase activating protein 42 [Source:HGNC Symbol;Acc:HGNC:26545]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0003085//negative regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0035024//negative regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity;GO:1904694//negative regulation of vascular associated smooth muscle contraction	--
ENSG00000165898	16.97	15.624	16.584	21.391	14.505	20.42	559	540	483	520	458	477	ISCA2	iron-sulfur cluster assembly 2 [Source:HGNC Symbol;Acc:HGNC:19857]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000165899	0.01	0	0.013	0.007	0.027	0	2	0	2	1	1	0	OTOGL	otogelin like [Source:HGNC Symbol;Acc:HGNC:26901]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0046556//alpha-L-arabinofuranosidase activity	GO:0007605//sensory perception of sound;GO:0046373//L-arabinose metabolic process	--
ENSG00000165905	28.216	27.47	32.081	29.874	32.532	28.481	1254	1401	1116	1040	1359	990	LARGE2	LARGE xylosyl- and glucuronyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16522]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K09668;K09668	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0035252//UDP-xylosyltransferase activity;GO:0042285//xylosyltransferase activity;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0008152//metabolic process;GO:0035269//protein O-linked mannosylation;GO:0046716//muscle cell cellular homeostasis	--
ENSG00000165912	22.565	23.799	23.914	26.313	26.136	27.88	812	864	633	692	770	740	PACSIN3	protein kinase C and casein kinase substrate in neurons 3 [Source:HGNC Symbol;Acc:HGNC:8572]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0019855//calcium channel inhibitor activity;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0030100//regulation of endocytosis;GO:0045806//negative regulation of endocytosis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051926//negative regulation of calcium ion transport;GO:0097320//plasma membrane tubulation	--
ENSG00000165914	14.939	15.899	18.158	16.008	13.123	16.508	717	817	587	592	535	562	TTC7B	tetratricopeptide repeat domain 7B [Source:HGNC Symbol;Acc:HGNC:19858]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000165915	25.395	27.881	28.256	32.637	31.11	31.238	1107	1219	934	1006	1101	1023	SLC39A13	solute carrier family 39 member 13 [Source:HGNC Symbol;Acc:HGNC:20859]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14719;K14719	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046873//metal ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0061448//connective tissue development;GO:0071577//zinc ion transmembrane transport	--
ENSG00000165916	75.615	76.897	79.122	80.728	69.244	69.609	2117	2133	1587	1610	1664	1324	PSMC3	"proteasome 26S subunit, ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9549]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03065;K03065;K03065;K03065;K03065;K03065;K03065;K03065;K03065	"GO:0000502//proteasome complex;GO:0000932//P-body;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034774//secretory granule lumen;GO:0043229//intracellular organelle;GO:1904813//ficolin-1-rich granule lumen"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0036402//proteasome-activating activity;GO:0042802//identical protein binding	GO:0006261//DNA-dependent DNA replication;GO:0030163//protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043921//modulation by host of viral transcription;GO:0044085//cellular component biogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1901800//positive regulation of proteasomal protein catabolic process	--
ENSG00000165917	0.167	0.325	0.093	0.312	0.117	0.356	5	11	2	7	3	8	RAPSN	receptor associated protein of the synapse [Source:HGNC Symbol;Acc:HGNC:9863]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0099634//postsynaptic specialization membrane	GO:0005515//protein binding;GO:0033130//acetylcholine receptor binding;GO:0035255//ionotropic glutamate receptor binding;GO:0043495//protein-membrane adaptor activity;GO:0046872//metal ion binding	"GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0043525//positive regulation of neuron apoptotic process;GO:1900075//positive regulation of neuromuscular synaptic transmission;GO:1901626//regulation of postsynaptic membrane organization;GO:1903540//establishment of protein localization to postsynaptic membrane"	--
ENSG00000165923	0.474	0.688	0.637	0.315	0.524	0.475	18	19	12	11	15	13	AGBL2	AGBL carboxypeptidase 2 [Source:HGNC Symbol;Acc:HGNC:26296]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0035610//protein side chain deglutamylation	--
ENSG00000165929	11.399	8.242	12.033	10.918	10.924	10.934	714	592	561	522	587	616	TC2N	"tandem C2 domains, nuclear [Source:HGNC Symbol;Acc:HGNC:19859]"	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function	-	--
ENSG00000165934	17.413	11.026	11.872	7.457	11.151	9.782	1225	1013	710	601	746	640	CPSF2	cleavage and polyadenylation specific factor 2 [Source:HGNC Symbol;Acc:HGNC:2325]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14402	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0016020//membrane	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006378//mRNA polyadenylation;GO:0006379//mRNA cleavage;GO:0006397//mRNA processing;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000165935	0	0	0	0	0	0	0	0	0	0	0	0	SMCO2	single-pass membrane protein with coiled-coil domains 2 [Source:HGNC Symbol;Acc:HGNC:34448]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000165943	24.214	22.292	23.968	24.613	23.632	27.552	1212	1121	885	914	999	1006	MOAP1	modulator of apoptosis 1 [Source:HGNC Symbol;Acc:HGNC:16658]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000165948	13.397	13.666	13.046	13.75	10.931	12.039	177	177	126	133	123	111	IFI27L1	interferon alpha inducible protein 27 like 1 [Source:HGNC Symbol;Acc:HGNC:19754]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway	--
ENSG00000165949	0.902	0.147	0.329	0	2.88	0.525	10	2	2	0	23	4	IFI27	interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0042802//identical protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044827//modulation by host of viral genome replication;GO:0045087//innate immune response;GO:0046825//regulation of protein export from nucleus;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway	--
ENSG00000165953	0	0	0	0	0	0	0	0	0	0	0	0	SERPINA12	serpin family A member 12 [Source:HGNC Symbol;Acc:HGNC:18359]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045721//negative regulation of gluconeogenesis;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0051055//negative regulation of lipid biosynthetic process;GO:0090181//regulation of cholesterol metabolic process;GO:0090207//regulation of triglyceride metabolic process	--
ENSG00000165959	1.549	1.36	0.976	0.597	0.783	1.091	295	265	153	117	175	210	CLMN	calmin [Source:HGNC Symbol;Acc:HGNC:19972]	-	-	-	-	GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007097//nuclear migration;GO:0008285//negative regulation of cell population proliferation;GO:0031175//neuron projection development	--
ENSG00000165966	0.094	0.189	0.021	0.154	0.154	0.215	8	12	1	9	10	12	PDZRN4	PDZ domain containing ring finger 4 [Source:HGNC Symbol;Acc:HGNC:30552]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000165970	0.02	0	0	0	0	0	1	0	0	0	0	0	SLC6A5	solute carrier family 6 member 5 [Source:HGNC Symbol;Acc:HGNC:11051]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K05038	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031045//dense core granule;GO:0098690//glycinergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0015187//glycine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015375//glycine:sodium symporter activity;GO:0046872//metal ion binding	"GO:0001504//neurotransmitter uptake;GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0015816//glycine transport;GO:0035725//sodium ion transmembrane transport;GO:0060012//synaptic transmission, glycinergic;GO:1903804//glycine import across plasma membrane"	--
ENSG00000165972	0.074	0	0	0	0	0	4	0	0	0	0	0	CCDC38	coiled-coil domain containing 38 [Source:HGNC Symbol;Acc:HGNC:26843]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	-	-	--
ENSG00000165973	0.816	0.617	0.588	1.149	1.481	0.825	46	37	26	56	78	33	NELL1	neural EGFL like 1 [Source:HGNC Symbol;Acc:HGNC:7750]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0005080//protein kinase C binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0033689//negative regulation of osteoblast proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:1903363//negative regulation of cellular protein catabolic process	--
ENSG00000165983	4.004	3.436	3.249	2.675	2.908	3.52	308	263	181	149	192	198	PTER	phosphotriesterase related [Source:HGNC Symbol;Acc:HGNC:9590]	-	-	-	-	GO:0070062//extracellular exosome	"GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0009056//catabolic process;GO:0030855//epithelial cell differentiation	--
ENSG00000165985	0.122	0.202	0.082	0.055	0.192	0.139	6	10	3	2	8	5	C1QL3	complement C1q like 3 [Source:HGNC Symbol;Acc:HGNC:19359]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0050807//regulation of synapse organization	--
ENSG00000165995	5.452	4.632	5.089	3.118	4.028	3.971	335	284	249	129	209	190	CACNB2	calcium voltage-gated channel auxiliary subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:1402]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04863;K04863;K04863;K04863;K04863;K04863;K04863	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0042383//sarcolemma;GO:0098684//photoreceptor ribbon synapse;GO:0098793//presynapse;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity;GO:0051015//actin filament binding;GO:0086007//voltage-gated calcium channel activity involved in cardiac muscle cell action potential;GO:0086056//voltage-gated calcium channel activity involved in AV node cell action potential;GO:0099635//voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0007601//visual perception;GO:0034765//regulation of ion transmembrane transport;GO:0051928//positive regulation of calcium ion transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0086045//membrane depolarization during AV node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098912//membrane depolarization during atrial cardiac muscle cell action potential;GO:0099533//positive regulation of presynaptic cytosolic calcium concentration;GO:0099703//induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1901843//positive regulation of high voltage-gated calcium channel activity;GO:1904879//positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	--
ENSG00000165996	67.061	64.401	60.825	69.051	61.666	79.528	2048	1964	1406	1513	1493	1767	HACD1	3-hydroxyacyl-CoA dehydratase 1 [Source:HGNC Symbol;Acc:HGNC:9639]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10703;K10703;K10703;K10703	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0016829//lyase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0080023//3R-hydroxyacyl-CoA dehydratase activity;GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process	--
ENSG00000165997	7.531	4.556	4.37	4.512	4.529	4.408	1120	681	480	497	569	477	ARL5B	ADP ribosylation factor like GTPase 5B [Source:HGNC Symbol;Acc:HGNC:23052]	-	-	-	-	GO:0005802//trans-Golgi network	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:1903292//protein localization to Golgi membrane	--
ENSG00000166002	8.803	14.405	9.359	6.419	10.17	8.224	176	228	122	86	107	98	SMCO4	single-pass membrane protein with coiled-coil domains 4 [Source:HGNC Symbol;Acc:HGNC:24810]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000166004	2.387	0.776	0.961	1.139	0.704	1.048	223	107	57	60	73	83	CEP295	centrosomal protein 295 [Source:HGNC Symbol;Acc:HGNC:29366]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:1990498//mitotic spindle microtubule	GO:0008017//microtubule binding	GO:0007099//centriole replication;GO:0010825//positive regulation of centrosome duplication;GO:0046599//regulation of centriole replication;GO:1901985//positive regulation of protein acetylation;GO:1903724//positive regulation of centriole elongation;GO:1904951//positive regulation of establishment of protein localization	--
ENSG00000166006	0	0	0	0	0	0	0	0	0	0	0	0	KCNC2	potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030673//axolemma;GO:0031982//vesicle;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0099508//voltage-gated ion channel activity involved in regulation of presynaptic membrane potential	GO:0001508//action potential;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0009636//response to toxic substance;GO:0009642//response to light intensity;GO:0014070//response to organic cyclic compound;GO:0014075//response to amine;GO:0021759//globus pallidus development;GO:0032026//response to magnesium ion;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0038060//nitric oxide-cGMP-mediated signaling pathway;GO:0045471//response to ethanol;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization;GO:0055085//transmembrane transport;GO:0071242//cellular response to ammonium ion;GO:0071732//cellular response to nitric oxide;GO:0071805//potassium ion transmembrane transport;GO:0097237//cellular response to toxic substance;GO:0099505//regulation of presynaptic membrane potential;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity;GO:1990089//response to nerve growth factor	--
ENSG00000166012	6.401	6.98	5.082	5.74	6.783	6.203	209	214	119	106	145	145	TAF1D	"TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005668//RNA polymerase transcription factor SL1 complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0034451//centriolar satellite;GO:0072686//mitotic spindle	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000166016	0.826	0.528	0.346	0.61	0.838	0.729	84	54	26	46	72	54	ABTB2	ankyrin repeat and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23842]	-	-	-	-	-	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0097237//cellular response to toxic substance	--
ENSG00000166024	4.181	3.859	3.568	1.754	2.523	3.312	235	252	157	88	137	154	R3HCC1L	R3H domain and coiled-coil containing 1 like [Source:HGNC Symbol;Acc:HGNC:23512]	-	-	-	-	GO:0035145//exon-exon junction complex	GO:0005515//protein binding	-	--
ENSG00000166025	37.158	36.457	38.017	28.422	30.333	30.543	6896	6774	5210	3905	4754	4122	AMOTL1	angiomotin like 1 [Source:HGNC Symbol;Acc:HGNC:17811]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06104	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0008180//COP9 signalosome;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0003365//establishment of cell polarity involved in ameboidal cell migration;GO:0016055//Wnt signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030334//regulation of cell migration;GO:0035329//hippo signaling	--
ENSG00000166033	194.002	202.428	119.707	173.121	194.196	170.55	7010	7456	3202	4585	5990	4468	HTRA1	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019838//growth factor binding;GO:0042802//identical protein binding	GO:0001890//placenta development;GO:0006508//proteolysis;GO:0012501//programmed cell death;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050687//negative regulation of defense response to virus;GO:0060718//chorionic trophoblast cell differentiation;GO:0097187//dentinogenesis	--
ENSG00000166035	0.077	0.032	0.03	0.09	0.211	0.045	4	1	1	3	8	1	LIPC	"lipase C, hepatic type [Source:HGNC Symbol;Acc:HGNC:6619]"	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04979//Cholesterol metabolism	K22283;K22283;K22283	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0034364//high-density lipoprotein particle	GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008970//phospholipase A1 activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0030169//low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034373//intermediate-density lipoprotein particle remodeling;GO:0034374//low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034382//chylomicron remnant clearance;GO:0034638//phosphatidylcholine catabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0070328//triglyceride homeostasis	--
ENSG00000166037	10.691	8.769	8.711	6.155	8.441	8.324	637.09	496.71	362.87	262.33	374.03	346.5	CEP57	centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043015//gamma-tubulin binding	GO:0007286//spermatid development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034453//microtubule anchoring;GO:0051260//protein homooligomerization	--
ENSG00000166046	7.863	6.198	6.524	3.732	5.858	6.105	302	219	171	104	197	195	TCP11L2	t-complex 11 like 2 [Source:HGNC Symbol;Acc:HGNC:28627]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000166049	0	0	0	0	0	0	0	0	0	0	0	0	PASD1	PAS domain containing repressor 1 [Source:HGNC Symbol;Acc:HGNC:20686]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:1990512//Cry-Per complex;GO:1990513//CLOCK-BMAL transcription complex	GO:0140297//DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0032922//circadian regulation of gene expression;GO:0042754//negative regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000166068	4.012	3.906	3.556	3.787	3.776	3.719	605	592	396	423	481	408	SPRED1	sprouty related EVH1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20249]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005173//stem cell factor receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0030291//protein serine/threonine kinase inhibitor activity	"GO:0006469//negative regulation of protein kinase activity;GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0043409//negative regulation of MAPK cascade;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0060979//vasculogenesis involved in coronary vascular morphogenesis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0090311//regulation of protein deacetylation;GO:1902747//negative regulation of lens fiber cell differentiation"	--
ENSG00000166069	0	0	0	0	0	0	0	0	0	0	0	0	TMCO5A	transmembrane and coiled-coil domains 5A [Source:HGNC Symbol;Acc:HGNC:28558]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000166073	7.9	9.527	9.95	9.766	9.964	9.875	641	761	578	587	652	583	GPR176	G protein-coupled receptor 176 [Source:HGNC Symbol;Acc:HGNC:32370]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0048511//rhythmic process;GO:0048512//circadian behavior	--
ENSG00000166086	27.584	29.534	28.752	24.796	26.091	27.191	2154.11	2318.31	1658.34	1434.35	1721.39	1545	JAM3	junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532]	Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases	Cellular community - eukaryotes;Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04530//Tight junction;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K06785;K06785;K06785;K06785	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0031941//filamentous actin;GO:0033010//paranodal junction;GO:0043220//Schmidt-Lanterman incisure;GO:0044291//cell-cell contact zone;GO:0070160//tight junction;GO:0098636//protein complex involved in cell adhesion	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0098632//cell-cell adhesion mediator activity	GO:0001525//angiogenesis;GO:0001780//neutrophil homeostasis;GO:0002250//adaptive immune response;GO:0002318//myeloid progenitor cell differentiation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002693//positive regulation of cellular extravasation;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0016477//cell migration;GO:0019226//transmission of nerve impulse;GO:0030010//establishment of cell polarity;GO:0030154//cell differentiation;GO:0033624//negative regulation of integrin activation;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0034333//adherens junction assembly;GO:0034394//protein localization to cell surface;GO:0035633//maintenance of blood-brain barrier;GO:0042552//myelination;GO:0045176//apical protein localization;GO:0090022//regulation of neutrophil chemotaxis;GO:0090138//regulation of actin cytoskeleton organization by cell-cell adhesion;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0097530//granulocyte migration;GO:0098609//cell-cell adhesion;GO:1902414//protein localization to cell junction;GO:1905710//positive regulation of membrane permeability	--
ENSG00000166090	0	0	0	0	0	0	0	0	0	0	0	0	IL25	interleukin 25 [Source:HGNC Symbol;Acc:HGNC:13765]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04657//IL-17 signaling pathway	K05493;K05493	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0030380//interleukin-17E receptor binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0008150//biological_process;GO:0009620//response to fungus;GO:0009624//response to nematode;GO:0030222//eosinophil differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000166091	0.321	0.249	0	0.18	0.147	0.111	8	4	0	2	3	2	CMTM5	CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0045662//negative regulation of myoblast differentiation	--
ENSG00000166105	0	0.033	0	0	0	0	0	2	0	0	0	0	GLB1L3	galactosidase beta 1 like 3 [Source:HGNC Symbol;Acc:HGNC:25147]	-	-	-	-	GO:0005773//vacuole	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004565//beta-galactosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000166106	8.934	9.024	3.663	8.572	10.014	9.322	1113	1130	337	791	1054	845	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif 15 [Source:HGNC Symbol;Acc:HGNC:16305]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0006508//proteolysis;GO:0007520//myoblast fusion;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization	--
ENSG00000166111	0.029	0.101	0.029	0.059	0.086	0	4	14	3	6	10	0	SVOP	SV2 related protein [Source:HGNC Symbol;Acc:HGNC:25417]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000166118	0	0	0	0	0	0	0	0	0	0	0	0	SPATA19	spermatogenesis associated 19 [Source:HGNC Symbol;Acc:HGNC:30614]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0036126//sperm flagellum;GO:0097225//sperm midpiece	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030382//sperm mitochondrion organization	--
ENSG00000166123	7.983	10.387	7.536	8.593	9.158	9.039	613	587	372	427	456	494	GPT2	glutamic--pyruvic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:18062]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Global and overview maps	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism"	K00814;K00814;K00814;K00814;K00814;K00814	GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0004021//L-alanine:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006103//2-oxoglutarate metabolic process;GO:0009058//biosynthetic process;GO:0042851//L-alanine metabolic process;GO:0042853//L-alanine catabolic process	--
ENSG00000166126	0	0.062	0.084	0	0.074	0	0	2	2	0	2	0	AMN	amnion associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:14604]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030139//endocytic vesicle;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0038024//cargo receptor activity	GO:0006898//receptor-mediated endocytosis;GO:0008104//protein localization;GO:0009235//cobalamin metabolic process;GO:0015031//protein transport;GO:0015889//cobalamin transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0097017//renal protein absorption	--
ENSG00000166128	9.83	7.894	9.069	7.696	9.854	7.457	650	481	460	331	426	402	RAB8B	"RAB8B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30273]"	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K07902	GO:0005768//endosome;GO:0005778//peroxisomal membrane;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0051286//cell tip;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0030911//TPR domain binding	GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0019882//antigen processing and presentation;GO:0031346//positive regulation of cell projection organization;GO:0032869//cellular response to insulin stimulus;GO:0045046//protein import into peroxisome membrane;GO:0048210//Golgi vesicle fusion to target membrane;GO:0051461//positive regulation of corticotropin secretion;GO:0072659//protein localization to plasma membrane;GO:0150115//cell-substrate junction organization	--
ENSG00000166130	6.804	6.223	5.458	4.379	5.442	6.138	308	250	168	141	196	178	IKBIP	IKBKB interacting protein [Source:HGNC Symbol;Acc:HGNC:26430]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0010165//response to X-ray	--
ENSG00000166133	4.1	3.517	3.505	4.238	4.131	4.903	168	162	127	142	145	147	RPUSD2	RNA pseudouridine synthase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24180]	-	-	-	-	GO:0005575//cellular_component	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity	GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0009451//RNA modification;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000166135	10.583	10.782	12.555	13.655	10.589	12.106	1455.39	1473	1207	1177	1345	1142	HIF1AN	hypoxia inducible factor 1 subunit alpha inhibitor [Source:HGNC Symbol;Acc:HGNC:17113]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005112//Notch binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0019826//oxygen sensor activity;GO:0031406//carboxylic acid binding;GO:0036139//peptidyl-histidine dioxygenase activity;GO:0036140//peptidyl-asparagine 3-dioxygenase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0051213//dioxygenase activity;GO:0071532//ankyrin repeat binding;GO:0102113//hypoxia-inducible factor-asparagine oxygenase activity	GO:0036138//peptidyl-histidine hydroxylation;GO:0042264//peptidyl-aspartic acid hydroxylation;GO:0042265//peptidyl-asparagine hydroxylation;GO:0045663//positive regulation of myoblast differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000166136	80.445	85.553	88.863	95.455	91.157	95.374	1131.95	1210.09	923.18	994.86	1083.34	976.79	NDUFB8	NADH:ubiquinone oxidoreductase subunit B8 [Source:HGNC Symbol;Acc:HGNC:7703]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000166140	10.151	11.606	11.168	12.671	10.141	14.37	279	304	222	240	245	260	ZFYVE19	zinc finger FYVE-type containing 19 [Source:HGNC Symbol;Acc:HGNC:20758]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0046872//metal ion binding	GO:0007049//cell cycle;GO:0009838//abscission;GO:0032466//negative regulation of cytokinesis;GO:0044878//mitotic cytokinesis checkpoint signaling;GO:0051301//cell division	--
ENSG00000166143	0	0	0	0	0	0	0	0	0	0	0	0	PPP1R14D	protein phosphatase 1 regulatory inhibitor subunit 14D [Source:HGNC Symbol;Acc:HGNC:14953]	-	-	-	-	GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity	GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:1905183//negative regulation of protein serine/threonine phosphatase activity;GO:1905184//positive regulation of protein serine/threonine phosphatase activity	--
ENSG00000166145	5.847	6.915	4.235	8.762	12.778	7.561	322	365	150	345	454	258	SPINT1	"serine peptidase inhibitor, Kunitz type 1 [Source:HGNC Symbol;Acc:HGNC:11246]"	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05215//Prostate cancer	K15619;K15619	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001843//neural tube closure;GO:0001892//embryonic placenta development;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030198//extracellular matrix organization;GO:0045687//positive regulation of glial cell differentiation;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060674//placenta blood vessel development;GO:0071773//cellular response to BMP stimulus;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000166147	100.914	101.149	76.847	56.503	68.766	60.447	19083	19373	10591	7728	11113	8171	FBN1	fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K06825	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005178//integrin binding;GO:0005179//hormone activity;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0001501//skeletal system development;GO:0001656//metanephros development;GO:0001822//kidney development;GO:0007165//signal transduction;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0033627//cell adhesion mediated by integrin;GO:0035582//sequestering of BMP in extracellular matrix;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0043010//camera-type eye development;GO:0045671//negative regulation of osteoclast differentiation;GO:0048048//embryonic eye morphogenesis;GO:0048050//post-embryonic eye morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:2001205//negative regulation of osteoclast development	--
ENSG00000166148	0	0.015	0	0	0	0	0	2	0	0	0	0	AVPR1A	arginine vasopressin receptor 1A [Source:HGNC Symbol;Acc:HGNC:895]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04072//Phospholipase D signaling pathway;ko04270//Vascular smooth muscle contraction	K04226;K04226;K04226;K04226	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle	GO:0004930//G protein-coupled receptor activity;GO:0005000//vasopressin receptor activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0031894//V1A vasopressin receptor binding;GO:0042277//peptide binding	GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0002125//maternal aggressive behavior;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007621//negative regulation of female receptivity;GO:0007625//grooming behavior;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010259//multicellular organism aging;GO:0010460//positive regulation of heart rate;GO:0014049//positive regulation of glutamate secretion;GO:0014902//myotube differentiation;GO:0019722//calcium-mediated signaling;GO:0021537//telencephalon development;GO:0030307//positive regulation of cell growth;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0032849//positive regulation of cellular pH reduction;GO:0035176//social behavior;GO:0035815//positive regulation of renal sodium excretion;GO:0042631//cellular response to water deprivation;GO:0042711//maternal behavior;GO:0042713//sperm ejaculation;GO:0043084//penile erection;GO:0045777//positive regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0051412//response to corticosterone;GO:0051970//negative regulation of transmission of nerve impulse;GO:0150104//transport across blood-brain barrier	--
ENSG00000166152	0	0	0	0	0	0	0	0	0	0	0	0	C16orf78	chromosome 16 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:28479]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000166153	0.438	0.306	0.85	0.251	0.233	0.204	7	11	19	9	7	6	DEPDC4	DEP domain containing 4 [Source:HGNC Symbol;Acc:HGNC:22952]	-	-	-	-	-	-	GO:0035556//intracellular signal transduction	--
ENSG00000166159	0.03	0.053	0.04	0.101	0.115	0.061	2	4	2	5	8	3	LRTM2	leucine rich repeats and transmembrane domains 2 [Source:HGNC Symbol;Acc:HGNC:32443]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0048495//Roundabout binding	GO:0007411//axon guidance;GO:0050919//negative chemotaxis;GO:0051965//positive regulation of synapse assembly	--
ENSG00000166160	0	0	0	0	0	0	0	0	0	0	0	0	OPN1MW2	"opsin 1, medium wave sensitive 2 [Source:HGNC Symbol;Acc:HGNC:26952]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000166164	29.087	28.792	25.428	19.508	22.054	23.888	1716.75	1695.85	1148.3	850.45	1082.05	1047.11	BRD7	bromodomain containing 7 [Source:HGNC Symbol;Acc:HGNC:14310]	Human Diseases	Cancer: specific types	ko05225//Hepatocellular carcinoma	K11723	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016586//RSC-type complex	GO:0000976//transcription cis-regulatory region binding;GO:0002039//p53 binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0070577//lysine-acetylated histone binding	"GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0035066//positive regulation of histone acetylation;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000166165	25.297	25.476	23.307	21.059	23.125	25.5	715	733	507	456	553	533	CKB	creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00933;K00933	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004111//creatine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0031625//ubiquitin protein ligase binding"	GO:0007420//brain development;GO:0016310//phosphorylation;GO:0019752//carboxylic acid metabolic process;GO:0021549//cerebellum development;GO:0021762//substantia nigra development;GO:0030644//cellular chloride ion homeostasis;GO:0046314//phosphocreatine biosynthetic process	--
ENSG00000166166	3.597	4.16	4.241	4.228	4.985	5.602	240	279	209	209	281	272	TRMT61A	tRNA methyltransferase 61A [Source:HGNC Symbol;Acc:HGNC:23790]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016429//tRNA (adenine-N1-)-methyltransferase activity;GO:0016740//transferase activity;GO:0061953//mRNA (adenine-N1-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0080009//mRNA methylation	--
ENSG00000166167	10.251	9.221	8.954	7.663	10.452	10.073	1152	1114	825	709	973	858	BTRC	beta-transducin repeat containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:1144]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Genetic Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems	"Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cell growth and death;Signal transduction;Folding, sorting and degradation;Cell growth and death;Signal transduction;Environmental adaptation"	ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm	K03362;K03362;K03362;K03362;K03362;K03362;K03362;K03362;K03362	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016874//ligase activity;GO:0045309//protein phosphorylated amino acid binding;GO:0046983//protein dimerization activity;GO:0061630//ubiquitin protein ligase activity;GO:1990756//ubiquitin ligase-substrate adaptor activity;GO:1990757//ubiquitin ligase activator activity	"GO:0000209//protein polyubiquitination;GO:0006470//protein dephosphorylation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031648//protein destabilization;GO:0033598//mammary gland epithelial cell proliferation;GO:0042752//regulation of circadian rhythm;GO:0042753//positive regulation of circadian rhythm;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043687//post-translational protein modification;GO:0045862//positive regulation of proteolysis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0051726//regulation of cell cycle;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0071407//cellular response to organic cyclic compound;GO:1904668//positive regulation of ubiquitin protein ligase activity"	--
ENSG00000166169	10.783	11.42	12.544	13.878	12.838	11.17	478	551	440	446	475	379	POLL	DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03410//Base excision repair;ko03450//Non-homologous end-joining	K03512;K03512	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0035861//site of double-strand break;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016829//lyase activity;GO:0034061//DNA polymerase activity;GO:0046872//metal ion binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity	"GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006289//nucleotide-excision repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0071897//DNA biosynthetic process"	--
ENSG00000166170	11.892	9.39	9.629	8.73	8.211	8.94	1077	917	648	630	674	633	BAG5	BAG cochaperone 5 [Source:HGNC Symbol;Acc:HGNC:941]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016020//membrane;GO:0016234//inclusion body;GO:0048471//perinuclear region of cytoplasm	GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0007030//Golgi organization;GO:0010977//negative regulation of neuron projection development;GO:0031397//negative regulation of protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0050821//protein stabilization;GO:0051438//regulation of ubiquitin-protein transferase activity;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0061084//negative regulation of protein refolding;GO:0070997//neuron death;GO:0090083//regulation of inclusion body assembly;GO:1900034//regulation of cellular response to heat;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000166171	17.115	16.877	19.256	14.844	17.763	12.835	272	275	231	175	230	152	DPCD	deleted in primary ciliary dyskinesia homolog (mouse) [Source:HGNC Symbol;Acc:HGNC:24542]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus	GO:0005515//protein binding	GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007283//spermatogenesis;GO:0007368//determination of left/right symmetry;GO:0021591//ventricular system development;GO:0021670//lateral ventricle development;GO:0021678//third ventricle development;GO:0030317//flagellated sperm motility;GO:0060972//left/right pattern formation	--
ENSG00000166173	9.66	7.964	9.426	8.022	8.401	6.882	547	452	399	360	381	403	LARP6	"La ribonucleoprotein 6, translational regulator [Source:HGNC Symbol;Acc:HGNC:24012]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005844//polysome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0035613//RNA stem-loop binding;GO:0048027//mRNA 5'-UTR binding;GO:1990825//sequence-specific mRNA binding	GO:0006396//RNA processing;GO:0006417//regulation of translation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0045727//positive regulation of translation;GO:1902416//positive regulation of mRNA binding	--
ENSG00000166181	22.847	20.171	23.512	20.37	20.834	24.411	1675	1510	1187	1121	1215	1317	API5	apoptosis inhibitor 5 [Source:HGNC Symbol;Acc:HGNC:594]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding	GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:2000270//negative regulation of fibroblast apoptotic process	--
ENSG00000166183	2.935	2.314	2.205	2.829	3.431	2.174	103	85	63	83	115	67	ASPG	asparaginase [Source:HGNC Symbol;Acc:HGNC:20123]	-	-	-	-	GO:0005829//cytosol	"GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0004067//asparaginase activity;GO:0004622//lysophospholipase activity;GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0016787//hydrolase activity;GO:0102545//phosphatidyl phospholipase B activity"	GO:0006520//cellular amino acid metabolic process;GO:0006629//lipid metabolic process;GO:0006813//potassium ion transport;GO:0009066//aspartate family amino acid metabolic process;GO:0016042//lipid catabolic process;GO:0071805//potassium ion transmembrane transport	--
ENSG00000166188	6.407	3.926	7.65	7.893	7.891	5.695	382	324	280	310	398	369	ZNF319	zinc finger protein 319 [Source:HGNC Symbol;Acc:HGNC:13644]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000166189	6.116	6.495	6.921	8.039	7.77	7.099	341	364	285	332	366	288	HPS6	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 [Source:HGNC Symbol;Acc:HGNC:18817]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0031084//BLOC-2 complex;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding	GO:0006996//organelle organization;GO:0007596//blood coagulation;GO:0030318//melanocyte differentiation;GO:0032418//lysosome localization;GO:0043473//pigmentation;GO:0046907//intracellular transport;GO:0060155//platelet dense granule organization;GO:0072657//protein localization to membrane;GO:1903232//melanosome assembly	--
ENSG00000166192	2.439	2.272	1.893	1.275	1.661	1.849	118	103	82	52	85	70	SENP8	"SUMO peptidase family member, NEDD8 specific [Source:HGNC Symbol;Acc:HGNC:22992]"	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019784//NEDD8-specific protease activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0043687//post-translational protein modification	--
ENSG00000166197	18.261	18.094	15.097	11.421	13.999	13.17	1225	1200	788	589	792	673	NOLC1	nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0031428//box C/D RNP complex;GO:0031429//box H/ACA snoRNP complex	GO:0000166//nucleotide binding;GO:0001093//TFIIB-class transcription factor binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008139//nuclear localization sequence binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0034512//box C/D RNA binding;GO:0034513//box H/ACA snoRNA binding;GO:0046982//protein heterodimerization activity;GO:0062064//box C/D snoRNP complex binding;GO:0062065//box H/ACA snoRNP complex binding	"GO:0000278//mitotic cell cycle;GO:0006364//rRNA processing;GO:0006417//regulation of translation;GO:0006970//response to osmotic stress;GO:0007000//nucleolus organization;GO:0008284//positive regulation of cell population proliferation;GO:0014029//neural crest formation;GO:0014032//neural crest cell development;GO:0033979//box H/ACA RNA metabolic process;GO:0042306//regulation of protein import into nucleus;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000166199	6.451	6.055	6.733	6.024	5.793	7.031	186	185	138	116	141	143	ALKBH3	"alkB homolog 3, alpha-ketoglutarate dependent dioxygenase [Source:HGNC Symbol;Acc:HGNC:30141]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0031418//L-ascorbic acid binding;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:1990930//mRNA N1-methyladenosine dioxygenase activity	GO:0006281//DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0035552//oxidative single-stranded DNA demethylation;GO:0035553//oxidative single-stranded RNA demethylation	--
ENSG00000166200	33.345	29.33	30.674	26.333	25.614	31.993	1401	1155	838	811	881	954	COPS2	COP9 signalosome subunit 2 [Source:HGNC Symbol;Acc:HGNC:30747]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000338//protein deneddylation;GO:0001833//inner cell mass cell proliferation;GO:0006366//transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008283//cell population proliferation;GO:0030182//neuron differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0045116//protein neddylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription;GO:2000434//regulation of protein neddylation"	--
ENSG00000166206	3.682	4.425	3.127	2.822	3.43	3.654	355	353	210	214	245	224	GABRB3	gamma-aminobutyric acid type A receptor subunit beta3 [Source:HGNC Symbol;Acc:HGNC:4083]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko04726//Serotonergic synapse;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05181;K05181;K05181;K05181;K05181;K05181	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042802//identical protein binding	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060021//roof of mouth development;GO:0071420//cellular response to histamine;GO:1902476//chloride transmembrane transport;GO:1904862//inhibitory synapse assembly"	--
ENSG00000166211	0	0	0	0	0	0	0	0	0	0	0	0	SPIC	Spi-C transcription factor [Source:HGNC Symbol;Acc:HGNC:29549]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001824//blastocyst development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000166220	0	0	0	0	0	0	0	0	0	0	0	0	TBATA	"thymus, brain and testes associated [Source:HGNC Symbol;Acc:HGNC:23511]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0036064//ciliary basal body	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000166224	8.419	6.027	5.649	4.941	5.323	6.112	680	726	500	422	539	533	SGPL1	sphingosine-1-phosphate lyase 1 [Source:HGNC Symbol;Acc:HGNC:10817]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K01634;K01634;K01634	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008117//sphinganine-1-phosphate aldolase activity;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0030170//pyridoxal phosphate binding	GO:0001553//luteinization;GO:0001570//vasculogenesis;GO:0001822//kidney development;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0008585//female gonad development;GO:0009791//post-embryonic development;GO:0010761//fibroblast migration;GO:0019752//carboxylic acid metabolic process;GO:0030097//hemopoiesis;GO:0030148//sphingolipid biosynthetic process;GO:0030149//sphingolipid catabolic process;GO:0033327//Leydig cell differentiation;GO:0040014//regulation of multicellular organism growth;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0097190//apoptotic signaling pathway	--
ENSG00000166225	16.361	20.299	14.709	15.301	20.073	13.17	2065	1838	1295	1042	1296	1288	FRS2	fibroblast growth factor receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:16971]	Organismal Systems;Human Diseases;Organismal Systems	Environmental adaptation;Cancer: overview;Nervous system	ko04714//Thermogenesis;ko05205//Proteoglycans in cancer;ko04722//Neurotrophin signaling pathway	K12461;K12461;K12461	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0019211//phosphatase activator activity	"GO:0001702//gastrulation with mouth forming second;GO:0001759//organ induction;GO:0002088//lens development in camera-type eye;GO:0003281//ventricular septum development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007405//neuroblast proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008595//anterior/posterior axis specification, embryo;GO:0030900//forebrain development;GO:0042981//regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0046619//lens placode formation involved in camera-type eye formation;GO:0050678//regulation of epithelial cell proliferation;GO:0050790//regulation of catalytic activity;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0070307//lens fiber cell development;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:2000726//negative regulation of cardiac muscle cell differentiation"	--
ENSG00000166226	69.301	73.338	68.038	60.296	55.447	57.11	2758	2933	2003	1775	1864	1652	CCT2	chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615]	-	-	-	-	GO:0002199//zona pellucida receptor complex;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex;GO:0005874//microtubule;GO:0035578//azurophil granule lumen;GO:0044297//cell body;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0050821//protein stabilization;GO:0051086//chaperone mediated protein folding independent of cofactor;GO:0051131//chaperone-mediated protein complex assembly;GO:0051973//positive regulation of telomerase activity;GO:0061077//chaperone-mediated protein folding;GO:0090666//scaRNA localization to Cajal body;GO:1901998//toxin transport;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000166228	55.379	60.093	59.305	64.921	63.736	68.45	904	986	715	785	879	813	PCBD1	pterin-4 alpha-carbinolamine dehydratase 1 [Source:HGNC Symbol;Acc:HGNC:8646]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00790//Folate biosynthesis	K01724;K01724	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003713//transcription coactivator activity;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005515//protein binding;GO:0008124//4-alpha-hydroxytetrahydrobiopterin dehydratase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding	"GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0019293//tyrosine biosynthetic process, by oxidation of phenylalanine;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000166233	11.796	11.769	13.177	12.841	11.712	14.633	1852.88	1751	1242	1017	1237	1050	ARIH1	ariadne RBR E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:689]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0019005//SCF ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0097413//Lewy body	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000166246	1.351	1.504	1.236	0.502	0.57	0.431	44.45	38.42	29.45	15	11	7	DNAAF8	dynein axonemal assembly factor 8 [Source:HGNC Symbol;Acc:HGNC:25081]	-	-	-	-	GO:0005737//cytoplasm;GO:0120293//dynein axonemal particle	GO:0070840//dynein complex binding	GO:0036158//outer dynein arm assembly	--
ENSG00000166250	0.115	0.076	0.065	0.078	0.204	0.119	12	8	5	6	18	9	CLMP	CXADR like membrane protein [Source:HGNC Symbol;Acc:HGNC:24039]	-	-	-	-	GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding	GO:0048565//digestive tract development	--
ENSG00000166257	10.888	10.966	7.753	4.824	5.374	5.729	1243	1269	671	422	527	493	SCN3B	sodium voltage-gated channel beta subunit 3 [Source:HGNC Symbol;Acc:HGNC:20665]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc	GO:0005244//voltage-gated ion channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0019871//sodium channel inhibitor activity;GO:0044325//transmembrane transporter binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007399//nervous system development;GO:0010460//positive regulation of heart rate;GO:0010765//positive regulation of sodium ion transport;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051899//membrane depolarization;GO:0060048//cardiac muscle contraction;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0061337//cardiac conduction;GO:0072659//protein localization to plasma membrane;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086010//membrane depolarization during action potential;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086014//atrial cardiac muscle cell action potential;GO:0086015//SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000166260	18.62	15.251	18.766	16.221	18.497	17.613	857.64	735.07	630.16	602.57	656.11	621.74	COX11	cytochrome c oxidase copper chaperone COX11 [Source:HGNC Symbol;Acc:HGNC:2261]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02258;K02258;K02258	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0032991//protein-containing complex	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0009055//electron transfer activity	GO:0022900//electron transport chain;GO:0033132//negative regulation of glucokinase activity;GO:0055065//metal ion homeostasis	--
ENSG00000166261	2.842	3.128	3.938	2.449	2.579	2.761	214	203	177	132	152	151	ZNF202	zinc finger protein 202 [Source:HGNC Symbol;Acc:HGNC:12994]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process"	zf-C2H2
ENSG00000166262	3.254	2.022	3.049	3.282	2.57	2.108	76.22	51.03	56.71	49.79	47.72	39.7	FAM227B	family with sequence similarity 227 member B [Source:HGNC Symbol;Acc:HGNC:26543]	-	-	-	-	-	-	-	--
ENSG00000166263	3.544	2.023	2.299	1.7	1.865	1.783	537	339.18	223	175	209	202	STXBP4	syntaxin binding protein 4 [Source:HGNC Symbol;Acc:HGNC:19694]	-	-	-	-	GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006605//protein targeting;GO:0006974//cellular response to DNA damage stimulus;GO:0008286//insulin receptor signaling pathway;GO:0010827//regulation of glucose transmembrane transport;GO:0010838//positive regulation of keratinocyte proliferation;GO:0050821//protein stabilization;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0071346//cellular response to interferon-gamma;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000166265	12.273	11.79	11.006	11.983	9.177	10.34	769	739	510	505	477	474	CYYR1	cysteine and tyrosine rich 1 [Source:HGNC Symbol;Acc:HGNC:16274]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000166266	5.5	4.376	3.798	3.291	3.994	4.413	704	467	318	256	381	377	CUL5	cullin 5 [Source:HGNC Symbol;Acc:HGNC:2556]	Human Diseases;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation"	ko05170//Human immunodeficiency virus 1 infection;ko04120//Ubiquitin mediated proteolysis	K10612;K10612	GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0090734//site of DNA damage	GO:0004842//ubiquitin-protein transferase activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0038023//signaling receptor activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0038128//ERBB2 signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000166268	0.305	0.362	0.529	0.395	0.529	0.18	18	13	13	10	13	8	MYRFL	myelin regulatory factor like [Source:HGNC Symbol;Acc:HGNC:26316]	-	-	-	-	GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0016540//protein autoprocessing;GO:0045893//positive regulation of transcription, DNA-templated"	NDT80/PhoG
ENSG00000166272	42.251	46.847	39.568	29.489	30.483	27.923	3610	4025	2498	1868	2202	1739	WBP1L	WW domain binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:23510]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0030097//hemopoiesis;GO:0031398//positive regulation of protein ubiquitination;GO:0038160//CXCL12-activated CXCR4 signaling pathway	--
ENSG00000166275	10.589	8.48	9.719	7.725	7.718	10.462	406	387	300	259	287	270	BORCS7	BLOC-1 related complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:23516]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex	GO:0005515//protein binding	GO:0032418//lysosome localization;GO:0051036//regulation of endosome size;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule	--
ENSG00000166278	7.487	8.098	5.656	6.654	6.208	4.771	306.96	324	186.97	218.11	248.87	173	C2	complement C2 [Source:HGNC Symbol;Acc:HGNC:1248]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K01332;K01332;K01332;K01332;K01332;K01332	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0032496//response to lipopolysaccharide;GO:0045087//innate immune response;GO:0097066//response to thyroid hormone;GO:2000427//positive regulation of apoptotic cell clearance"	--
ENSG00000166289	1.305	1.338	0.945	0.843	0.931	1.33	46	43	24	22	27	32	PLEKHF1	pleckstrin homology and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20764]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding;GO:0070273//phosphatidylinositol-4-phosphate binding	GO:0006915//apoptotic process;GO:0007032//endosome organization;GO:0010508//positive regulation of autophagy;GO:0016050//vesicle organization;GO:0072659//protein localization to plasma membrane;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000166292	0.247	0.137	0.122	0.445	0.39	0.68	9	5	2	12	12	18	TMEM100	transmembrane protein 100 [Source:HGNC Symbol;Acc:HGNC:25607]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0003197//endocardial cushion development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0007219//Notch signaling pathway;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0043491//protein kinase B signaling;GO:0045603//positive regulation of endothelial cell differentiation;GO:0050848//regulation of calcium-mediated signaling;GO:0051930//regulation of sensory perception of pain;GO:0060842//arterial endothelial cell differentiation;GO:0071773//cellular response to BMP stimulus;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000166295	10.128	10.77	9.866	11.915	10.125	12.034	696	743	497.97	604	593	602	ANAPC16	anaphase promoting complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:26976]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K25229;K25229;K25229;K25229;K25229	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol"	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle	--
ENSG00000166311	42.929	48.077	45.926	46.547	46.122	41.426	2093	2307	1629	1666	1898	1444	SMPD1	sphingomyelin phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:11120]	Metabolism;Cellular Processes;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Cell growth and death;Transport and catabolism;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04217//Necroptosis;ko04142//Lysosome;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K12350;K12350;K12350;K12350;K12350	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005768//endosome;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036019//endolysosome;GO:0042599//lamellar body;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding;GO:0061750//acid sphingomyelin phosphodiesterase activity"	GO:0001778//plasma membrane repair;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0008203//cholesterol metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009615//response to virus;GO:0010212//response to ionizing radiation;GO:0023021//termination of signal transduction;GO:0034340//response to type I interferon;GO:0034612//response to tumor necrosis factor;GO:0034644//cellular response to UV;GO:0035307//positive regulation of protein dephosphorylation;GO:0042060//wound healing;GO:0042220//response to cocaine;GO:0043065//positive regulation of apoptotic process;GO:0043407//negative regulation of MAP kinase activity;GO:0045807//positive regulation of endocytosis;GO:0046513//ceramide biosynthetic process;GO:0046718//viral entry into host cell;GO:0070555//response to interleukin-1;GO:0071277//cellular response to calcium ion	--
ENSG00000166313	25.711	28.11	31.283	33.668	30.753	32.671	1407	1422	1263	1285	1393	1186	APBB1	amyloid beta precursor protein binding family B member 1 [Source:HGNC Symbol;Acc:HGNC:581]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K04529	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0042995//cell projection;GO:0045202//synapse	GO:0001540//amyloid-beta binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042393//histone binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0070064//proline-rich region binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006939//smooth muscle contraction;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050714//positive regulation of protein secretion;GO:1902807//negative regulation of cell cycle G1/S phase transition"	--
ENSG00000166317	0.491	0.928	0.127	0.569	0.626	0.305	42	65	8	36	47	19	SYNPO2L	synaptopodin 2 like [Source:HGNC Symbol;Acc:HGNC:23532]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016607//nuclear speck;GO:0030018//Z disc;GO:0030054//cell junction	GO:0003779//actin binding;GO:0005515//protein binding	GO:0003007//heart morphogenesis;GO:0032233//positive regulation of actin filament bundle assembly;GO:0035025//positive regulation of Rho protein signal transduction;GO:0045214//sarcomere organization;GO:0051496//positive regulation of stress fiber assembly	--
ENSG00000166321	0.176	0.262	0.643	0.341	0.354	0.38	7	11	13	9	12	11	NUDT13	nudix hydrolase 13 [Source:HGNC Symbol;Acc:HGNC:18827]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000210//NAD+ diphosphatase activity;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0046872//metal ion binding	GO:0006734//NADH metabolic process;GO:0006742//NADP catabolic process;GO:0015949//nucleobase-containing small molecule interconversion	--
ENSG00000166323	0.173	0.661	0.426	0.204	0.059	0	5	16	7	4	1	0	C11orf65	chromosome 11 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:28519]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding	GO:0090258//negative regulation of mitochondrial fission;GO:1903215//negative regulation of protein targeting to mitochondrion	--
ENSG00000166326	8.634	7.667	8.058	6.421	6.873	6.333	2327	2077	1604	1282	1565	1242	TRIM44	tripartite motif containing 44 [Source:HGNC Symbol;Acc:HGNC:19016]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0002230//positive regulation of defense response to virus by host;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0061944//negative regulation of protein K48-linked ubiquitination;GO:1901224//positive regulation of NIK/NF-kappaB signaling"	--
ENSG00000166329	0	0	0	0	0	0	0	0	0	0	0	0	CCDC182	coiled-coil domain containing 182 [Source:HGNC Symbol;Acc:HGNC:49392]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008585//female gonad development	--
ENSG00000166333	56.142	58.044	62.393	57.535	57.312	55.552	2010.44	2067.24	1643.18	1516.62	1735.34	1441.15	ILK	integrin linked kinase [Source:HGNC Symbol;Acc:HGNC:6040]	Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Cellular community - eukaryotes;Development and regeneration;Infectious disease: bacterial;Endocrine system;Cancer: specific types	ko05131//Shigellosis;ko04510//Focal adhesion;ko04360//Axon guidance;ko05100//Bacterial invasion of epithelial cells;ko03320//PPAR signaling pathway;ko05213//Endometrial cancer	K06272;K06272;K06272;K06272;K06272;K06272	GO:0001725//stress fiber;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0106310//protein serine kinase activity	"GO:0000902//cell morphogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0003151//outflow tract morphogenesis;GO:0006468//protein phosphorylation;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009967//positive regulation of signal transduction;GO:0010761//fibroblast migration;GO:0014044//Schwann cell development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0021675//nerve development;GO:0022011//myelination in peripheral nervous system;GO:0030030//cell projection organization;GO:0030513//positive regulation of BMP signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042327//positive regulation of phosphorylation;GO:0043491//protein kinase B signaling;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045669//positive regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070527//platelet aggregation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000178//negative regulation of neural precursor cell proliferation"	--
ENSG00000166337	20.161	23.747	21.284	27.43	22.697	26.932	957.56	1011.76	748.82	742.38	835.66	754.85	TAF10	TATA-box binding protein associated factor 10 [Source:HGNC Symbol;Acc:HGNC:11543]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03134	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0033276//transcription factor TFTC complex;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0019899//enzyme binding;GO:0030331//estrogen receptor binding;GO:0042802//identical protein binding;GO:0070063//RNA polymerase binding;GO:1990841//promoter-specific chromatin binding	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0001889//liver development;GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0010468//regulation of gene expression;GO:0016573//histone acetylation;GO:0016578//histone deubiquitination;GO:0034622//cellular protein-containing complex assembly;GO:0035264//multicellular organism growth;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051101//regulation of DNA binding;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0070365//hepatocyte differentiation"	--
ENSG00000166340	180.239	184.678	191.335	243.235	238.39	243.148	12997	13418	10203	13012	14422	12633	TPP1	tripeptidyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:2073]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K01279	GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0042470//melanosome;GO:0043202//lysosomal lumen;GO:0045121//membrane raft;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0035727//lysophosphatidic acid binding;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0120146//sulfatide binding	"GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0007040//lysosome organization;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0030163//protein catabolic process;GO:0030855//epithelial cell differentiation;GO:0043171//peptide catabolic process;GO:0045453//bone resorption;GO:0050885//neuromuscular process controlling balance;GO:0070198//protein localization to chromosome, telomeric region;GO:1905146//lysosomal protein catabolic process"	--
ENSG00000166341	16.57	17.927	18.524	15.377	17.749	15.976	3682	4004	3040	2531	3332	2583	DCHS1	dachsous cadherin-related 1 [Source:HGNC Symbol;Acc:HGNC:13681]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04392//Hippo signaling pathway - multiple species;ko04391//Hippo signaling pathway - fly	K16507;K16507	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0045177//apical part of cell	GO:0005509//calcium ion binding;GO:0045296//cadherin binding	GO:0000902//cell morphogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0003007//heart morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0003192//mitral valve formation;GO:0003273//cell migration involved in endocardial cushion formation;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007389//pattern specification process;GO:0009653//anatomical structure morphogenesis;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016477//cell migration;GO:0021915//neural tube development;GO:0022008//neurogenesis;GO:0034332//adherens junction organization;GO:0035329//hippo signaling;GO:0036342//post-anal tail morphogenesis;GO:0043931//ossification involved in bone maturation;GO:0048565//digestive tract development;GO:0072006//nephron development;GO:0072137//condensed mesenchymal cell proliferation;GO:0072659//protein localization to plasma membrane;GO:0090102//cochlea development;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000166342	1.718	1.586	1.303	0.361	1.07	0.355	197	170	115	30	63	36	NETO1	neuropilin and tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:13823]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding	GO:0007613//memory;GO:0008542//visual learning;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0097120//receptor localization to synapse;GO:2000312//regulation of kainate selective glutamate receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000166343	0.378	0.1	0.404	0.294	0.071	0.137	19	5	15	9	3	5	MSS51	MSS51 mitochondrial translational activator [Source:HGNC Symbol;Acc:HGNC:21000]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000166347	25.584	23.191	26.221	27.729	21.038	28.712	457	433	341	374	329	361	CYB5A	cytochrome b5 type A [Source:HGNC Symbol;Acc:HGNC:2570]	-	-	-	-	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0022900//electron transport chain;GO:1902600//proton transmembrane transport	--
ENSG00000166348	9.629	10.509	8.28	9.281	9.618	11.484	1050	1086	697	794	968	861	USP54	ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513]	-	-	-	-	-	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding	GO:0016579//protein deubiquitination	--
ENSG00000166349	0.373	0.663	0.644	0.731	0.442	0.533	51	91	65	74	51	53	RAG1	recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831]	Environmental Information Processing;Human Diseases	Signal transduction;Immune disease	ko04068//FoxO signaling pathway;ko05340//Primary immunodeficiency	K10628;K10628	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0097519//DNA recombinase complex;GO:1905347//endodeoxyribonuclease complex	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:1990238//double-stranded DNA endodeoxyribonuclease activity	GO:0002250//adaptive immune response;GO:0002331//pre-B cell allelic exclusion;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006955//immune response;GO:0008152//metabolic process;GO:0008542//visual learning;GO:0010390//histone monoubiquitination;GO:0030183//B cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0033151//V(D)J recombination;GO:0043029//T cell homeostasis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045580//regulation of T cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0048538//thymus development;GO:0051865//protein autoubiquitination;GO:0070233//negative regulation of T cell apoptotic process;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:2000822//regulation of behavioral fear response	Others
ENSG00000166351	0	0	0	0	0	0	0	0	0	0	0	0	POTED	POTE ankyrin domain family member D [Source:HGNC Symbol;Acc:HGNC:23822]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000166352	46.377	41.19	43.663	38.947	37.476	38.378	904	807	640	558	610	530	IFTAP	intraflagellar transport associated protein [Source:HGNC Symbol;Acc:HGNC:25142]	-	-	-	-	GO:0005829//cytosol;GO:0097731//9+0 non-motile cilium	GO:0005515//protein binding;GO:0120160//intraciliary transport particle A binding	GO:0007283//spermatogenesis;GO:0007340//acrosome reaction;GO:0009566//fertilization	--
ENSG00000166359	0	0	0	0	0	0	0	0	0	0	0	0	WDR88	WD repeat domain 88 [Source:HGNC Symbol;Acc:HGNC:26999]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000166363	0	0	0	0	0	0	0	0	0	0	0	0	OR10A5	olfactory receptor family 10 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:15131]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000166368	0	0	0	0	0	0	0	0	0	0	0	0	OR2D2	olfactory receptor family 2 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8244]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000166377	9.112	8.386	8.535	8.273	8.892	8.249	645.44	637.32	453.96	473.33	583.68	460.14	ATP9B	ATPase phospholipid transporting 9B (putative) [Source:HGNC Symbol;Acc:HGNC:13541]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140326//ATPase-coupled intramembrane lipid transporter activity	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006897//endocytosis;GO:0015914//phospholipid transport;GO:0045332//phospholipid translocation"	--
ENSG00000166387	72.631	78.25	73.133	58.932	64.65	65.922	4431	4680	3259	2709	3298	2937	PPFIBP2	PPFIA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9250]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0048786//presynaptic active zone	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007528//neuromuscular junction development;GO:0050808//synapse organization	--
ENSG00000166391	0	0	0	0.048	0	0	0	0	0	2	0	0	MOGAT2	monoacylglycerol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:23248]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K14457;K14457;K14457	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990578//perinuclear endoplasmic reticulum membrane	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0006651//diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0050892//intestinal absorption	--
ENSG00000166394	43.929	51.246	43.433	41.806	39.832	35.112	1030	1190	756	709	773	600	CYB5R2	cytochrome b5 reductase 2 [Source:HGNC Symbol;Acc:HGNC:24376]	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0071949//FAD binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008202//steroid metabolic process;GO:0015701//bicarbonate transport;GO:0016126//sterol biosynthetic process	--
ENSG00000166396	0.11	0.118	0.033	0	0	0.034	5	2	1	0	0	1	SERPINB7	serpin family B member 7 [Source:HGNC Symbol;Acc:HGNC:13902]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0090362//positive regulation of platelet-derived growth factor production	--
ENSG00000166398	10.939	11.566	10.915	11.907	11.695	11.496	1491	1562	1117	1198	1369	1159	GARRE1	granule associated Rac and RHOG effector 1 [Source:HGNC Symbol;Acc:HGNC:29016]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:1905762//CCR4-NOT complex binding	GO:0016601//Rac protein signal transduction	--
ENSG00000166401	0.974	1.24	1.421	1.208	1.272	0.73	51	75	55	44	54	33	SERPINB8	serpin family B member 8 [Source:HGNC Symbol;Acc:HGNC:8952]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0090136//epithelial cell-cell adhesion	--
ENSG00000166402	9.18	9.14	10.434	8.336	7.4	10.858	1048	1081	848	704	759	794	TUB	TUB bipartite transcription factor [Source:HGNC Symbol;Acc:HGNC:12406]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane	GO:0001664//G protein-coupled receptor binding;GO:0044877//protein-containing complex binding;GO:0120160//intraciliary transport particle A binding	"GO:0006909//phagocytosis;GO:0006910//phagocytosis, recognition;GO:0007605//sensory perception of sound;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0042073//intraciliary transport;GO:0045494//photoreceptor cell maintenance;GO:0050766//positive regulation of phagocytosis;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:0061512//protein localization to cilium;GO:0097500//receptor localization to non-motile cilium;GO:1903546//protein localization to photoreceptor outer segment"	Tub
ENSG00000166405	1.922	2.076	2.121	1.818	1.613	1.816	119	115	97	84	91	80	RIC3	RIC3 acetylcholine receptor chaperone [Source:HGNC Symbol;Acc:HGNC:30338]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0005515//protein binding;GO:0033130//acetylcholine receptor binding;GO:0044183//protein folding chaperone	"GO:0006457//protein folding;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007271//synaptic transmission, cholinergic;GO:0034394//protein localization to cell surface;GO:0034622//cellular protein-containing complex assembly;GO:2000010//positive regulation of protein localization to cell surface"	--
ENSG00000166407	8.293	11.083	8.766	6.431	6.958	8.572	185	253	146	106	133	143	LMO1	LIM domain only 1 [Source:HGNC Symbol;Acc:HGNC:6641]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046013//regulation of T cell homeostatic proliferation	--
ENSG00000166411	14.28	12.115	17.148	13.968	17.889	19.012	876.68	762.76	638.43	596	714.45	785.73	IDH3A	isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:5384]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K00030;K00030;K00030;K00030;K00030	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005962//mitochondrial isocitrate dehydrogenase complex (NAD+)	"GO:0000287//magnesium ion binding;GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046872//metal ion binding;GO:0051287//NAD binding"	GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process	--
ENSG00000166415	0.074	0.023	0.079	0.062	0	0.031	9	2	7	4	0	2	WDR72	WD repeat domain 72 [Source:HGNC Symbol;Acc:HGNC:26790]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0022617//extracellular matrix disassembly;GO:0031214//biomineral tissue development;GO:0070166//enamel mineralization;GO:0072659//protein localization to plasma membrane	--
ENSG00000166426	5.422	5.199	8.491	7.32	4.717	3.95	83	80	96	83	61	44	CRABP1	cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0001972//retinoic acid binding;GO:0005501//retinoid binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0019841//retinol binding	GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0015908//fatty acid transport;GO:0034653//retinoic acid catabolic process	--
ENSG00000166428	0	0	0	0	0	0	0	0	0	0	0	0	PLD4	phospholipase D family member 4 [Source:HGNC Symbol;Acc:HGNC:23792]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism	K16860;K16860;K16860	GO:0005634//nucleus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0045335//phagocytic vesicle	GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0016787//hydrolase activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0002376//immune system process;GO:0006259//DNA metabolic process;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0016042//lipid catabolic process;GO:0045087//innate immune response;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1900015//regulation of cytokine production involved in inflammatory response	--
ENSG00000166432	0.906	0.688	0.79	0.541	0.878	0.361	59	45	38	27	51	18	ZMAT1	zinc finger matrin-type 1 [Source:HGNC Symbol;Acc:HGNC:29377]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000166435	10.143	8.846	9.275	8.709	9.244	7.786	758.9	633.81	519.57	442.67	545.35	467.74	XRRA1	X-ray radiation resistance associated 1 [Source:HGNC Symbol;Acc:HGNC:18868]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0010165//response to X-ray	--
ENSG00000166436	0.488	0.674	0.5	0.663	0.858	1.246	108	110	82	102	104	97	TRIM66	tripartite motif containing 66 [Source:HGNC Symbol;Acc:HGNC:29005]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016235//aggresome	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000166439	3.831	3.677	3.6	2.949	2.872	3.272	623.1	601.19	432.43	355.33	394.65	387.26	RNF169	ring finger protein 169 [Source:HGNC Symbol;Acc:HGNC:26961]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0035861//site of double-strand break	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031491//nucleosome binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:2000780//negative regulation of double-strand break repair	--
ENSG00000166441	451.992	475.681	437.418	516.653	409.362	410.049	9329	9892	6781	7946	7210	6321	RPL27A	ribosomal protein L27a [Source:HGNC Symbol;Acc:HGNC:10329]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02900;K02900	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000166444	50.602	47.321	48.956	37.981	41.803	42.368	2238	2297	1684	1427	1788	1358	DENND2B	DENN domain containing 2B [Source:HGNC Symbol;Acc:HGNC:11350]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0055037//recycling endosome	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000166446	2.323	2.334	2.417	1.691	2.045	2.154	406	410	312	219	302	274	CDYL2	chromodomain Y like 2 [Source:HGNC Symbol;Acc:HGNC:23030]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000166448	13.602	14.749	7.413	12.118	17.464	11.483	838	915	337	552	912	516	TMEM130	transmembrane protein 130 [Source:HGNC Symbol;Acc:HGNC:25429]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000166450	3.212	3.773	2.226	2.091	3.458	3.34	543	502	297	254	380	300	PRTG	protogenin [Source:HGNC Symbol;Acc:HGNC:26373]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0007411//axon guidance;GO:0050768//negative regulation of neurogenesis	--
ENSG00000166451	3.809	5.518	5.567	3.889	2.781	4.119	190	239	143	122	117	147	CENPN	centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0005515//protein binding	GO:0007059//chromosome segregation;GO:0051382//kinetochore assembly	--
ENSG00000166452	14.074	16.007	14.263	16.093	15.254	16.98	281	295	209	258	279	212	AKIP1	A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0034446//substrate adhesion-dependent cell spreading;GO:1901222//regulation of NIK/NF-kappaB signaling	--
ENSG00000166454	21.845	20.607	18.855	17.55	18.556	19.76	2214	2098	1418	1318	1593	1459	ATMIN	ATM interactor [Source:HGNC Symbol;Acc:HGNC:29034]	-	-	-	-	GO:0005634//nucleus;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070840//dynein complex binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0010628//positive regulation of gene expression;GO:0044458//motile cilium assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902857//positive regulation of non-motile cilium assembly"	zf-C2H2
ENSG00000166455	0.25	0.691	0.733	0.484	0.01	0.429	9.46	24.68	20.27	12.84	0.29	12.02	C16orf46	chromosome 16 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:26525]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	-	-	--
ENSG00000166471	8.473	6.849	9.448	6.124	6.974	9.268	618	523	431	329	412	511	TMEM41B	transmembrane protein 41B [Source:HGNC Symbol;Acc:HGNC:28948]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity	GO:0000045//autophagosome assembly;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0007399//nervous system development;GO:0017121//plasma membrane phospholipid scrambling;GO:0032365//intracellular lipid transport;GO:0044830//modulation by host of viral RNA genome replication	--
ENSG00000166473	4.215	3.648	4.927	4.78	4.362	4.942	292	224	186	249	246	224	PKD1L2	polycystin 1 like 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:21715]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding	GO:0006811//ion transport;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport	--
ENSG00000166477	6.369	6.824	6.491	4.299	4.929	5.57	286	308	214	143	187	182	LEO1	"LEO1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:30401]"	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0016593//Cdc73/Paf1 complex	GO:0005515//protein binding;GO:1990269//RNA polymerase II C-terminal domain phosphoserine binding	GO:0001711//endodermal cell fate commitment;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006378//mRNA polyadenylation;GO:0010390//histone monoubiquitination;GO:0016055//Wnt signaling pathway;GO:0016570//histone modification;GO:0019827//stem cell population maintenance;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033523//histone H2B ubiquitination;GO:0045638//negative regulation of myeloid cell differentiation	--
ENSG00000166478	5.801	6.055	5.466	5.329	4.368	5.542	309	292	189	163	163	215	ZNF143	zinc finger protein 143 [Source:HGNC Symbol;Acc:HGNC:12928]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006359//regulation of transcription by RNA polymerase III;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:1905382//positive regulation of snRNA transcription by RNA polymerase II"	zf-C2H2
ENSG00000166479	10.302	7.373	8.637	6.288	6.914	8.158	948	695	581	448	535	538	TMX3	thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane	GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016853//isomerase activity	GO:0018171//peptidyl-cysteine oxidation	--
ENSG00000166482	89.116	108.696	51.814	17.858	23.199	20.816	3374	4137	1448	500	742	574	MFAP4	microfibril associated protein 4 [Source:HGNC Symbol;Acc:HGNC:7035]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0071953//elastic fiber	GO:0003823//antigen binding;GO:0005102//signaling receptor binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0097367//carbohydrate derivative binding	"GO:0001867//complement activation, lectin pathway;GO:0007155//cell adhesion;GO:0009650//UV protection;GO:0010712//regulation of collagen metabolic process;GO:0048251//elastic fiber assembly;GO:0071493//cellular response to UV-B;GO:0097435//supramolecular fiber organization"	--
ENSG00000166483	11.026	11.372	10.975	10.874	9.344	13.237	674	658	507	370	435	451	WEE1	WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761]	Human Diseases;Cellular Processes	Infectious disease: viral;Cell growth and death	ko05170//Human immunodeficiency virus 1 infection;ko04110//Cell cycle	K06632;K06632	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030010//establishment of cell polarity;GO:0048812//neuron projection morphogenesis;GO:0051301//cell division;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000166484	8.438	12.115	9.54	7.293	8.987	10.905	528.84	663	442.89	338	441	446.84	MAPK7	mitogen-activated protein kinase 7 [Source:HGNC Symbol;Acc:HGNC:6880]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes	Signal transduction;Cancer: overview;Endocrine system;Cardiovascular disease;Nervous system;Immune system;Endocrine system;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko05206//MicroRNAs in cancer;ko04921//Oxytocin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04722//Neurotrophin signaling pathway;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko04540//Gap junction	K04464;K04464;K04464;K04464;K04464;K04464;K04464;K04464	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019933//cAMP-mediated signaling;GO:0030154//cell differentiation;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0035556//intracellular signal transduction;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0043066//negative regulation of apoptotic process;GO:0045765//regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050728//negative regulation of inflammatory response;GO:0051247//positive regulation of protein metabolic process;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0060761//negative regulation of response to cytokine stimulus;GO:0070301//cellular response to hydrogen peroxide;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071363//cellular response to growth factor stimulus;GO:0071499//cellular response to laminar fluid shear stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000166501	5.354	5.101	5.752	5.814	5.832	5.322	683	666	497	511	584	485	PRKCB	protein kinase C beta [Source:HGNC Symbol;Acc:HGNC:9395]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Signal transduction;Infectious disease: viral;Signal transduction;Immune system;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Endocrine system;Immune system;Nervous system;Neurodegenerative disease;Infectious disease: parasitic;Circulatory system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Nervous system;Nervous system;Endocrine and metabolic disease;Endocrine system;Infectious disease: parasitic;Cancer: overview;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Substance dependence;Cellular community - eukaryotes;Nervous system;Endocrine system;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Digestive system;Cancer: specific types;Endocrine system;Substance dependence;Nervous system;Endocrine system;Signal transduction;Nervous system;Excretory system;Digestive system;Excretory system	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko05017//Spinocerebellar ataxia;ko05140//Leishmaniasis;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04931//Insulin resistance;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko05231//Choline metabolism in cancer;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko04971//Gastric acid secretion;ko05223//Non-small cell lung cancer;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662;K19662	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008091//spectrin;GO:0016020//membrane;GO:0044305//calyx of Held;GO:0070062//extracellular exosome;GO:0099523//presynaptic cytosol	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005080//protein kinase C binding;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030374//nuclear receptor coactivator activity;GO:0035403//histone kinase activity (H3-T6 specific);GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0106310//protein serine kinase activity	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006915//apoptotic process;GO:0007077//mitotic nuclear membrane disassembly;GO:0007165//signal transduction;GO:0010827//regulation of glucose transmembrane transport;GO:0010829//negative regulation of glucose transmembrane transport;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0035408//histone H3-T6 phosphorylation;GO:0035556//intracellular signal transduction;GO:0042113//B cell activation;GO:0042953//lipoprotein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071322//cellular response to carbohydrate stimulus;GO:0099171//presynaptic modulation of chemical synaptic transmission;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000166503	32.153	28.69	25.667	16.284	20.661	20.819	1585	1474	945	650	776	715.13	HDGFL3	HDGF like 3 [Source:HGNC Symbol;Acc:HGNC:24937]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0008017//microtubule binding;GO:0008083//growth factor activity;GO:0015631//tubulin binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007026//negative regulation of microtubule depolymerization;GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0046785//microtubule polymerization	--
ENSG00000166507	5.959	6.041	6.637	6.166	6.158	5.609	448.15	473.33	382.1	351.81	405.55	318.12	NDST2	N-deacetylase and N-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:7681]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02577;K02577	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0008146//sulfotransferase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0050119//N-acetylglucosamine deacetylase activity	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0008152//metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030210//heparin biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process"	--
ENSG00000166508	15.196	16.61	15.449	12.583	12.787	16.481	736	798	547	460	522	590	MCM7	minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950]	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03030//DNA replication	K02210;K02210	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0042555//MCM complex;GO:0071162//CMG complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017116//single-stranded DNA helicase activity	GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:0042325//regulation of phosphorylation;GO:0071310//cellular response to organic substance;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000166509	0	0	0	0	0.236	0	0	0	0	0	8	0	CLEC3A	C-type lectin domain family 3 member A [Source:HGNC Symbol;Acc:HGNC:2052]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0030246//carbohydrate binding	GO:0001501//skeletal system development;GO:0001503//ossification	--
ENSG00000166510	1.052	0.338	0.163	0.415	0.27	0.573	29	19	10	10	19	17	CCDC68	coiled-coil domain containing 68 [Source:HGNC Symbol;Acc:HGNC:24350]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding	GO:0008104//protein localization;GO:0034454//microtubule anchoring at centrosome;GO:0035556//intracellular signal transduction	--
ENSG00000166523	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4E	C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05152//Tuberculosis;ko04625//C-type lectin receptor signaling pathway	K10059;K10059	GO:0001891//phagocytic cup;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0038187//pattern recognition receptor activity;GO:0046872//metal ion binding;GO:0051861//glycolipid binding	GO:0001819//positive regulation of cytokine production;GO:0002221//pattern recognition receptor signaling pathway;GO:0002292//T cell differentiation involved in immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0038094//Fc-gamma receptor signaling pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0061760//antifungal innate immune response	--
ENSG00000166526	11.265	11.231	12.653	9.951	11.695	11.345	565.53	618.44	478.63	395.89	477.17	422.86	ZNF3	zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045321//leukocyte activation"	zf-C2H2
ENSG00000166527	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4D	C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554]	Organismal Systems	Immune system	ko04625//C-type lectin receptor signaling pathway	K10058	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0034987//immunoglobulin receptor binding;GO:0038187//pattern recognition receptor activity;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0002292//T cell differentiation involved in immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0030887//positive regulation of myeloid dendritic cell activation;GO:0038094//Fc-gamma receptor signaling pathway;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0061760//antifungal innate immune response	--
ENSG00000166529	5.856	7.123	6.139	5.027	6.517	6	193.47	224.56	161.37	128.11	192.83	157.14	ZSCAN21	zinc finger and SCAN domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13104]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051321//meiotic cell cycle"	zf-C2H2
ENSG00000166532	7.227	7.072	8.457	4.425	7.797	5.688	652	658	504	337	602	408	RIMKLB	ribosomal modification protein rimK like family member B [Source:HGNC Symbol;Acc:HGNC:29228]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism"	K18310;K18310	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046872//metal ion binding;GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity;GO:0072591//citrate-L-glutamate ligase activity"	GO:0006464//cellular protein modification process;GO:0009064//glutamine family amino acid metabolic process	--
ENSG00000166535	0.029	0.085	0.051	0.097	0.051	0.446	2	6	4	5	3	6	A2ML1	alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0052548//regulation of endopeptidase activity	--
ENSG00000166546	0.115	0.097	0	0.067	0.132	0.054	6	5	0	3	5	2	BEAN1	brain expressed associated with NEDD4 1 [Source:HGNC Symbol;Acc:HGNC:24160]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K19324	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000166548	7.894	8.605	7.019	9.54	8.724	7.084	363	427	257	304	345	265	TK2	thymidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11831]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00857;K00857;K00857	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004137//deoxycytidine kinase activity;GO:0004797//thymidine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019136//deoxynucleoside kinase activity;GO:0019206//nucleoside kinase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0009117//nucleotide metabolic process;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0043097//pyrimidine nucleoside salvage;GO:0044249//cellular biosynthetic process;GO:0046092//deoxycytidine metabolic process;GO:0046104//thymidine metabolic process;GO:0071897//DNA biosynthetic process;GO:1901576//organic substance biosynthetic process	--
ENSG00000166557	76.733	82.9	76.918	75.999	75.407	73.859	2363	2545	1725	1702	1925	1627	TMED3	transmembrane p24 trafficking protein 3 [Source:HGNC Symbol;Acc:HGNC:28889]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	-	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport	--
ENSG00000166558	0	0.121	0.078	0	0.066	0	0	3	2	0	1	0	SLC38A8	solute carrier family 38 member 8 [Source:HGNC Symbol;Acc:HGNC:32434]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015171//amino acid transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport	--
ENSG00000166562	35.716	31.43	33.366	41.383	35.97	35.935	598	534	419	511	523	442	SEC11C	"SEC11 homolog C, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:23400]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K13280	GO:0005783//endoplasmic reticulum;GO:0005787//signal peptidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis	--
ENSG00000166569	0.025	0	0	0	0	0	1	0	0	0	0	0	CPLX4	complexin 4 [Source:HGNC Symbol;Acc:HGNC:24330]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15295	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031201//SNARE complex;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0007601//visual perception;GO:0016079//synaptic vesicle exocytosis;GO:0046928//regulation of neurotransmitter secretion;GO:0050896//response to stimulus	--
ENSG00000166573	0	0	0	0	0	0.006	0	0	0	0	0	1	GALR1	galanin receptor 1 [Source:HGNC Symbol;Acc:HGNC:4132]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04230	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004966//galanin receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051464//positive regulation of cortisol secretion	--
ENSG00000166575	15.162	13.076	13.686	13.1	14.308	14.203	1161	1072	798	833	888	834	TMEM135	transmembrane protein 135 [Source:HGNC Symbol;Acc:HGNC:26167]	-	-	-	-	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0007031//peroxisome organization;GO:0009409//response to cold;GO:0032094//response to food;GO:0090140//regulation of mitochondrial fission	--
ENSG00000166578	1.063	1.113	0.916	0.93	0.701	1.451	35	40	22	23	19	35	IQCD	IQ motif containing D [Source:HGNC Symbol;Acc:HGNC:25168]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000166579	8.784	8.319	9.989	6.982	7.99	7.137	381	342	290	236	299	240	NDEL1	nudE neurodevelopment protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:17620]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005635//nuclear envelope;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0008021//synaptic vesicle;GO:0030424//axon;GO:0031252//cell leading edge;GO:0043203//axon hillock;GO:0044297//cell body;GO:0060053//neurofilament cytoskeleton;GO:0090724//central region of growth cone;GO:1904115//axon cytoplasm"	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0043014//alpha-tubulin binding;GO:0044877//protein-containing complex binding;GO:0048487//beta-tubulin binding;GO:0070012//oligopeptidase activity	GO:0000132//establishment of mitotic spindle orientation;GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0001833//inner cell mass cell proliferation;GO:0006508//proteolysis;GO:0007020//microtubule nucleation;GO:0007059//chromosome segregation;GO:0007100//mitotic centrosome separation;GO:0007399//nervous system development;GO:0008090//retrograde axonal transport;GO:0008286//insulin receptor signaling pathway;GO:0010975//regulation of neuron projection development;GO:0016477//cell migration;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021955//central nervous system neuron axonogenesis;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0032418//lysosome localization;GO:0033157//regulation of intracellular protein transport;GO:0043547//positive regulation of GTPase activity;GO:0045773//positive regulation of axon extension;GO:0047496//vesicle transport along microtubule;GO:0048680//positive regulation of axon regeneration;GO:0051081//nuclear membrane disassembly;GO:0051303//establishment of chromosome localization;GO:0051642//centrosome localization;GO:0060052//neurofilament cytoskeleton organization;GO:0090630//activation of GTPase activity;GO:1900029//positive regulation of ruffle assembly;GO:1990138//neuron projection extension	--
ENSG00000166582	6.565	7.147	6.459	9.136	7.266	6.609	179	186	129	167	158	132	CENPV	centromere protein V [Source:HGNC Symbol;Acc:HGNC:29920]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031965//nuclear membrane;GO:0051233//spindle midzone"	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016846//carbon-sulfur lyase activity;GO:0046872//metal ion binding	GO:0001667//ameboidal-type cell migration;GO:0007049//cell cycle;GO:0031508//pericentric heterochromatin assembly;GO:0032467//positive regulation of cytokinesis;GO:0033044//regulation of chromosome organization;GO:0034508//centromere complex assembly;GO:0051301//cell division	--
ENSG00000166589	0.083	0	0	0	0.028	0	1	0	0	0	1	0	CDH16	cadherin 16 [Source:HGNC Symbol;Acc:HGNC:1755]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000166592	3.829	3.969	4.382	3.076	3.596	3.719	116	121	98	69	92	82	RRAD	"RRAD, Ras related glycolysis inhibitor and calcium channel regulator [Source:HGNC Symbol;Acc:HGNC:10446]"	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005525//GTP binding	GO:0007264//small GTPase mediated signal transduction;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1901842//negative regulation of high voltage-gated calcium channel activity	--
ENSG00000166595	15.51	15.869	19.389	21.055	21.387	19.188	215	221	199	217	251	194	CIAO2B	cytosolic iron-sulfur assembly component 2B [Source:HGNC Symbol;Acc:HGNC:24261]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0071817//MMXD complex;GO:0097361//CIA complex	GO:0005515//protein binding	GO:0007059//chromosome segregation;GO:0016226//iron-sulfur cluster assembly;GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000166596	1.633	1.47	1.018	0.697	0.342	0.357	34	30	18	15	13	7	CFAP52	cilia and flagella associated protein 52 [Source:HGNC Symbol;Acc:HGNC:16053]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0005515//protein binding	GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0061966//establishment of left/right asymmetry	--
ENSG00000166598	240.712	208.588	166.679	159.229	175.126	179.206	13747	12046	7047	6745	8469	7488	HSP90B1	heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	"Cancer: overview;Signal transduction;Infectious disease: bacterial;Cardiovascular disease;Cancer: overview;Folding, sorting and degradation;Cardiovascular disease;Endocrine system;Cancer: specific types;Immune system;Endocrine system"	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05132//Salmonella infection;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko04141//Protein processing in endoplasmic reticulum;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko05215//Prostate cancer;ko04657//IL-17 signaling pathway;ko04918//Thyroid hormone synthesis	K09487;K09487;K09487;K09487;K09487;K09487;K09487;K09487;K09487;K09487;K09487	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0033018//sarcoplasmic reticulum lumen;GO:0034663//endoplasmic reticulum chaperone complex;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0051082//unfolded protein binding	"GO:0001666//response to hypoxia;GO:0006457//protein folding;GO:0015031//protein transport;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031247//actin rod assembly;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0051208//sequestering of calcium ion;GO:0071318//cellular response to ATP"	--
ENSG00000166603	0.028	0.028	0	0.076	0	0	1	1	0	2	0	0	MC4R	melanocortin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6932]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04202	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding;GO:0031625//ubiquitin protein ligase binding;GO:0042562//hormone binding;GO:0042923//neuropeptide binding	GO:0002024//diet induced thermogenesis;GO:0006112//energy reserve metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007631//feeding behavior;GO:0019222//regulation of metabolic process;GO:0030073//insulin secretion;GO:0032868//response to insulin;GO:0045780//positive regulation of bone resorption;GO:0060259//regulation of feeding behavior;GO:1903998//regulation of eating behavior;GO:1990680//response to melanocyte-stimulating hormone;GO:2000252//negative regulation of feeding behavior;GO:2000821//regulation of grooming behavior	--
ENSG00000166619	24.077	26.555	25.328	33.093	29.746	29.087	998	1112	783	1021	1052	886	BLCAP	BLCAP apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:1055]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0030262//apoptotic nuclear changes	--
ENSG00000166634	0	0	0	0	0	0	0	0	0	0	0	0	SERPINB12	serpin family B member 12 [Source:HGNC Symbol;Acc:HGNC:14220]	-	-	-	-	GO:0001533//cornified envelope;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0101003//ficolin-1-rich granule membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity	GO:0002244//hematopoietic progenitor cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0042177//negative regulation of protein catabolic process	--
ENSG00000166664	0.432	0.563	0.329	0.243	0.226	0.133	28.81	26.68	16.11	4.52	12.75	5.6	CHRFAM7A	CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Cancer: overview;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse;ko05033//Nicotine addiction	K04809;K04809;K04809;K04809;K04809;K04809;K04809	GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015464//acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0034766//negative regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:1903049//negative regulation of acetylcholine-gated cation channel activity"	--
ENSG00000166669	2.752	2.619	1.549	2.111	2.801	1.62	100	114	60	77	94	48	ATF7IP2	activating transcription factor 7 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:20397]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly"	--
ENSG00000166670	0.166	0.027	0	0	0	0	2	1	0	0	0	0	MMP10	matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process	--
ENSG00000166676	1.264	1.505	1.586	1.228	1.461	1.408	80.08	105.06	82.18	63.19	71	63.04	TVP23A	trans-golgi network vesicle protein 23 homolog A [Source:HGNC Symbol;Acc:HGNC:20398]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding	GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport	--
ENSG00000166681	136.117	137.008	131.327	141.426	129.636	142.858	2372	2405	1687	1825	1916	1813	BEX3	brain expressed X-linked 3 [Source:HGNC Symbol;Acc:HGNC:13388]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12465	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005102//signaling receptor binding;GO:0005123//death receptor binding;GO:0005163//nerve growth factor receptor binding;GO:0005515//protein binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000166682	0.784	1.015	1.111	0.996	0.958	1.032	34	45	33	31	34	33	TMPRSS5	transmembrane serine protease 5 [Source:HGNC Symbol;Acc:HGNC:14908]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006897//endocytosis	--
ENSG00000166685	11.014	13.397	11.442	11.575	12.316	12.43	657.76	729.53	495.04	522.86	644.15	465.65	COG1	component of oligomeric golgi complex 1 [Source:HGNC Symbol;Acc:HGNC:6545]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0070085//glycosylation"	--
ENSG00000166689	17.809	16.639	19.748	17.186	17.489	21.577	1462	1543	1314	1043	1378	1259	PLEKHA7	pleckstrin homology domain containing A7 [Source:HGNC Symbol;Acc:HGNC:27049]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0030054//cell junction;GO:0046930//pore complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0070097//delta-catenin binding	GO:0044331//cell-cell adhesion mediated by cadherin;GO:0045218//zonula adherens maintenance;GO:0046931//pore complex assembly;GO:0090136//epithelial cell-cell adhesion	--
ENSG00000166704	5.05	4.654	4.434	3.638	4.483	4.45	414	384	268	217	305	250	ZNF606	zinc finger protein 606 [Source:HGNC Symbol;Acc:HGNC:25879]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000166707	0.216	0.163	0.067	0.288	0.194	0.248	13	10	3	13	10	11	ZCCHC18	zinc finger CCHC-type containing 18 [Source:HGNC Symbol;Acc:HGNC:32459]	-	-	-	-	GO:0005634//nucleus	GO:0046872//metal ion binding	-	--
ENSG00000166710	838.191	843.673	954.945	1076.924	962.038	1016.668	16086	16339	13433	15419	15598	14325	B2M	beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04612//Antigen processing and presentation	K08055;K08055;K08055;K08055;K08055;K08055	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0031905//early endosome lumen;GO:0035580//specific granule lumen;GO:0042612//MHC class I protein complex;GO:0042613//MHC class II protein complex;GO:0042824//MHC class I peptide loading complex;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1990712//HFE-transferrin receptor complex	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	"GO:0001895//retina homeostasis;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002726//positive regulation of T cell cytokine production;GO:0006826//iron ion transport;GO:0006955//immune response;GO:0007608//sensory perception of smell;GO:0007611//learning or memory;GO:0010977//negative regulation of neuron projection development;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0032092//positive regulation of protein binding;GO:0033077//T cell differentiation in thymus;GO:0034756//regulation of iron ion transport;GO:0042026//protein refolding;GO:0045646//regulation of erythrocyte differentiation;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050768//negative regulation of neurogenesis;GO:0050870//positive regulation of T cell activation;GO:0051289//protein homotetramerization;GO:0055072//iron ion homeostasis;GO:0071281//cellular response to iron ion;GO:0071283//cellular response to iron(III) ion;GO:0071316//cellular response to nicotine;GO:0090647//modulation of age-related behavioral decline;GO:1900121//negative regulation of receptor binding;GO:1900122//positive regulation of receptor binding;GO:1904434//positive regulation of ferrous iron binding;GO:1904437//positive regulation of transferrin receptor binding;GO:1990000//amyloid fibril formation;GO:2000774//positive regulation of cellular senescence;GO:2000978//negative regulation of forebrain neuron differentiation"	--
ENSG00000166716	10.868	9.689	11.438	11.563	10.209	12.955	1345	1269	1075	1069	1171	1171	ZNF592	zinc finger protein 592 [Source:HGNC Symbol;Acc:HGNC:28986]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000166734	71.031	58.225	55.15	37.786	51.434	50.441	5710	4726	3262	2254	3212	2934	GOLM2	golgi membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:24892]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000166736	0	0	0	0	0	0	0	0	0	0	0	0	HTR3A	5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297]	Organismal Systems;Organismal Systems	Nervous system;Sensory system	ko04726//Serotonergic synapse;ko04742//Taste transduction	K04819;K04819	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032154//cleavage furrow;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1904602//serotonin-activated cation-selective channel complex	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0022850//serotonin-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000166741	5.058	6.725	2.044	3.753	3.934	3.199	205	281	63	116	132	96	NNMT	nicotinamide N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:7861]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K00541;K00541	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008112//nicotinamide N-methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0016740//transferase activity;GO:0030760//pyridine N-methyltransferase activity	GO:0006769//nicotinamide metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010243//response to organonitrogen compound;GO:0010967//regulation of polyamine biosynthetic process;GO:0031060//regulation of histone methylation;GO:0031100//animal organ regeneration;GO:0032259//methylation;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0045722//positive regulation of gluconeogenesis;GO:0051569//regulation of histone H3-K4 methylation;GO:0090312//positive regulation of protein deacetylation	--
ENSG00000166743	0	0.059	0	0	0	0	0	1	0	0	0	0	ACSM1	acyl-CoA synthetase medium chain family member 1 [Source:HGNC Symbol;Acc:HGNC:18049]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00650//Butanoate metabolism;ko00785//Lipoic acid metabolism	K23756;K23756;K23756	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0015645//fatty acid ligase activity;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0018858//benzoate-CoA ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0102391//decanoate-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0006805//xenobiotic metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0018874//benzoate metabolic process;GO:0019395//fatty acid oxidation;GO:0019605//butyrate metabolic process;GO:0042632//cholesterol homeostasis	--
ENSG00000166747	34.172	32.056	30.574	23.433	27.956	29.149	3375.39	3274.92	2344.88	1920	2429.96	2276.95	AP1G1	adaptor related protein complex 1 subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:555]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12391;K12391	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030121//AP-1 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0097708//intracellular vesicle;GO:0098588//bounding membrane of organelle	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding;GO:0035615//clathrin adaptor activity;GO:0140312//cargo adaptor activity	GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006896//Golgi to vacuole transport;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032438//melanosome organization;GO:0035646//endosome to melanosome transport;GO:0043323//positive regulation of natural killer cell degranulation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0060155//platelet dense granule organization;GO:0090160//Golgi to lysosome transport;GO:0110010//basolateral protein secretion;GO:1903232//melanosome assembly	--
ENSG00000166750	7.229	5.343	4.379	4.268	5.364	3.941	1134	850	477	487	617	453	SLFN5	schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0005524//ATP binding	GO:0030154//cell differentiation	--
ENSG00000166762	0.11	0.19	0.033	0.044	0.043	0	7	1	2	1	3	0	CATSPER2	cation channel sperm associated 2 [Source:HGNC Symbol;Acc:HGNC:18810]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0048240//sperm capacitation;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000166780	13.555	12.772	11.053	10.405	10.846	7.394	537	534	325	311	373	208	BMERB1	bMERB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19213]	-	-	-	-	GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding	GO:0007026//negative regulation of microtubule depolymerization;GO:0021822//negative regulation of cell motility involved in cerebral cortex radial glia guided migration	--
ENSG00000166783	19.807	15.212	16.319	11.635	12.535	16.048	2547	2251	1657	1348	1651	1446	MARF1	meiosis regulator and mRNA stability factor 1 [Source:HGNC Symbol;Acc:HGNC:29562]	-	-	-	-	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:1903231//mRNA binding involved in posttranscriptional gene silencing;GO:1905762//CCR4-NOT complex binding	GO:0006302//double-strand break repair;GO:0007143//female meiotic nuclear division;GO:0010468//regulation of gene expression;GO:0016441//posttranscriptional gene silencing;GO:0030154//cell differentiation;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000166788	4.315	5.211	6.218	5.052	4.53	3.809	139	168	142	119	124	89	SAAL1	serum amyloid A like 1 [Source:HGNC Symbol;Acc:HGNC:25158]	-	-	-	-	GO:0005581//collagen trimer;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003674//molecular_function	GO:1901647//positive regulation of synoviocyte proliferation	--
ENSG00000166793	0.927	0.702	0.462	0.437	1.032	0.429	33	26	13	11	24	13	YPEL4	yippee like 4 [Source:HGNC Symbol;Acc:HGNC:18328]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0046872//metal ion binding	-	--
ENSG00000166794	387.553	402.908	379.822	447.071	400.829	383.353	7190.71	7508.75	5202.64	6139.7	6280.32	5172.16	PPIB	peptidylprolyl isomerase B [Source:HGNC Symbol;Acc:HGNC:9255]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005790//smooth endoplasmic reticulum;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0034663//endoplasmic reticulum chaperone complex;GO:0042470//melanosome;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0051082//unfolded protein binding;GO:0070063//RNA polymerase binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0030593//neutrophil chemotaxis;GO:0040018//positive regulation of multicellular organism growth;GO:0044794//positive regulation by host of viral process;GO:0044829//positive regulation by host of viral genome replication;GO:0050821//protein stabilization;GO:0060348//bone development;GO:0061077//chaperone-mediated protein folding	--
ENSG00000166796	0	0.11	0	0	0	0	0	2	0	0	0	0	LDHC	lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0070062//extracellular exosome;GO:1990204//oxidoreductase complex	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0006089//lactate metabolic process;GO:0006090//pyruvate metabolic process;GO:0006754//ATP biosynthetic process;GO:0019244//lactate biosynthetic process from pyruvate;GO:0019516//lactate oxidation;GO:0019752//carboxylic acid metabolic process;GO:0030317//flagellated sperm motility;GO:0032787//monocarboxylic acid metabolic process	--
ENSG00000166797	31.626	31.944	37.707	33.239	27.584	32.685	520	522	455	384	379	388	CIAO2A	cytosolic iron-sulfur assembly component 2A [Source:HGNC Symbol;Acc:HGNC:26235]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097361//CIA complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007059//chromosome segregation;GO:0016226//iron-sulfur cluster assembly;GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000166800	0	0	0	0	0	0	0	0	0	0	0	0	LDHAL6A	lactate dehydrogenase A like 6A [Source:HGNC Symbol;Acc:HGNC:28335]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0019752//carboxylic acid metabolic process	--
ENSG00000166801	3.852	4.404	4.102	2.813	4.017	3.192	315	349	239	196	273	207	FAM111A	FAM111 trypsin like peptidase A [Source:HGNC Symbol;Acc:HGNC:24725]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0016540//protein autoprocessing;GO:0031297//replication fork processing;GO:0045071//negative regulation of viral genome replication;GO:0106300//protein-DNA covalent cross-linking repair	--
ENSG00000166803	0.861	0.302	0.37	1.031	0.77	0.168	14.63	7	8	18.65	17.73	5.41	PCLAF	PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007098//centrosome cycle;GO:0009411//response to UV;GO:0019985//translesion synthesis;GO:0051726//regulation of cell cycle	--
ENSG00000166813	2.927	3.511	3.702	3.2	3.828	3.293	266	321.95	259	219.93	267	227	KIF7	kinesin family member 7 [Source:HGNC Symbol;Acc:HGNC:30497]	Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K18806;K18806;K18806	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000166816	1.129	1.453	1.847	2.543	3.037	1.981	47	61	57	79	108	60	LDHD	lactate dehydrogenase D [Source:HGNC Symbol;Acc:HGNC:19708]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K00102;K00102	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane	GO:0003824//catalytic activity;GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0005515//protein binding;GO:0008720//D-lactate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding	GO:1903457//lactate catabolic process	--
ENSG00000166819	0.235	0.017	0.068	0.045	0.313	0.069	4	1	3	2	16	3	PLIN1	perilipin 1 [Source:HGNC Symbol;Acc:HGNC:9076]	Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems	Environmental adaptation;Signal transduction;Endocrine system;Endocrine system	ko04714//Thermogenesis;ko04371//Apelin signaling pathway;ko03320//PPAR signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K08768;K08768;K08768;K08768	GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0070417//cellular response to cold	--
ENSG00000166821	5.209	5.548	7.397	6.925	6.232	7.149	232	231	220	203	256	231	PEX11A	peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13351	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0007031//peroxisome organization;GO:0007165//signal transduction;GO:0016557//peroxisome membrane biogenesis;GO:0016559//peroxisome fission;GO:0044375//regulation of peroxisome size;GO:0050873//brown fat cell differentiation	--
ENSG00000166822	4.883	4.621	5.161	4.845	4.138	5.25	452.79	421.66	346.84	294.68	301.71	347	TMEM170A	transmembrane protein 170A [Source:HGNC Symbol;Acc:HGNC:29577]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006998//nuclear envelope organization;GO:0051292//nuclear pore complex assembly;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000166823	0.264	0.789	1.372	1.011	1.043	0.545	6	18	23	17	20	9	MESP1	mesoderm posterior bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:29658]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0001707//mesoderm formation;GO:0001947//heart looping;GO:0003007//heart morphogenesis;GO:0003139//secondary heart field specification;GO:0003143//embryonic heart tube morphogenesis;GO:0003210//cardiac atrium formation;GO:0003211//cardiac ventricle formation;GO:0003236//sinus venosus morphogenesis;GO:0003241//growth involved in heart morphogenesis;GO:0003259//cardioblast anterior-lateral migration;GO:0003260//cardioblast migration;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007369//gastrulation;GO:0008078//mesodermal cell migration;GO:0010467//gene expression;GO:0022008//neurogenesis;GO:0023019//signal transduction involved in regulation of gene expression;GO:0032525//somite rostral/caudal axis specification;GO:0035481//positive regulation of Notch signaling pathway involved in heart induction;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0042664//negative regulation of endodermal cell fate specification;GO:0045446//endothelial cell differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048368//lateral mesoderm development;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0060913//cardiac cell fate determination;GO:0060921//sinoatrial node cell differentiation;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0060975//cardioblast migration to the midline involved in heart field formation;GO:0070368//positive regulation of hepatocyte differentiation;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway"	bHLH
ENSG00000166825	0.064	0.039	0.018	0	0.031	0.07	2	3	1	0	2	4	ANPEP	"alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]"	Metabolism;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Immune system;Metabolism of other amino acids;Endocrine system	ko01100//Metabolic pathways;ko04640//Hematopoietic cell lineage;ko00480//Glutathione metabolism;ko04614//Renin-angiotensin system	K11140;K11140;K11140;K11140	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0038023//signaling receptor activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0001525//angiogenesis;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0030154//cell differentiation;GO:0043171//peptide catabolic process;GO:0046718//viral entry into host cell	--
ENSG00000166828	0.028	0.014	0	0.019	0	0	2	1	0	1	0	0	SCNN1G	sodium channel epithelial 1 subunit gamma [Source:HGNC Symbol;Acc:HGNC:10602]	Organismal Systems;Organismal Systems	Sensory system;Excretory system	ko04742//Taste transduction;ko04960//Aldosterone-regulated sodium reabsorption	K04827;K04827	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0034706//sodium channel complex;GO:0070062//extracellular exosome	GO:0005216//ion channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0050699//WW domain binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0008217//regulation of blood pressure;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0036254//cellular response to amiloride;GO:0050891//multicellular organismal water homeostasis;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050914//sensory perception of salty taste;GO:0050915//sensory perception of sour taste;GO:0055078//sodium ion homeostasis;GO:0071468//cellular response to acidic pH;GO:0098719//sodium ion import across plasma membrane;GO:1904045//cellular response to aldosterone;GO:1904117//cellular response to vasopressin	--
ENSG00000166831	4.092	2.806	3.495	3.911	4.164	5.757	159	118	108	120	143	171	RBPMS2	"RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098]"	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0030514//negative regulation of BMP signaling pathway;GO:0048557//embryonic digestive tract morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051151//negative regulation of smooth muscle cell differentiation	--
ENSG00000166833	8.432	8.365	7.667	6.023	7.657	6.947	1447	1431	932	750	1051	851	NAV2	neuron navigator 2 [Source:HGNC Symbol;Acc:HGNC:15997]	-	-	-	-	GO:0005614//interstitial matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031012//extracellular matrix	GO:0000166//nucleotide binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043138//3'-5' DNA helicase activity	GO:0003025//regulation of systemic arterial blood pressure by baroreceptor feedback;GO:0007399//nervous system development;GO:0007605//sensory perception of sound;GO:0007608//sensory perception of smell;GO:0007626//locomotory behavior;GO:0021554//optic nerve development;GO:0021563//glossopharyngeal nerve development;GO:0021564//vagus nerve development;GO:0022008//neurogenesis;GO:0032508//DNA duplex unwinding	--
ENSG00000166839	2.778	3.689	3.475	2.45	3.406	3.294	127	154	111	102	130	104	ANKDD1A	ankyrin repeat and death domain containing 1A [Source:HGNC Symbol;Acc:HGNC:28002]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000166840	0.614	0.436	0.23	0.55	0.277	0.554	14	11	6	7	6	8	GLYATL1	glycine-N-acyltransferase like 1 [Source:HGNC Symbol;Acc:HGNC:30519]	-	-	-	-	GO:0005739//mitochondrion	GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047946//glutamine N-acyltransferase activity;GO:0047961//glycine N-acyltransferase activity	GO:0006541//glutamine metabolic process	--
ENSG00000166845	1.471	0.995	0.787	0.562	0.736	0.806	108	69	56	29	41	43	C18orf54	chromosome 18 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:13796]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0008285//negative regulation of cell population proliferation	--
ENSG00000166847	20.711	21.657	22.598	21.854	21.089	18.571	2804	2742	2122	2076	2290	1890	DCTN5	dynactin subunit 5 [Source:HGNC Symbol;Acc:HGNC:24594]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10427;K10427;K10427;K10427;K10427	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031965//nuclear membrane"	GO:0005515//protein binding	GO:0003281//ventricular septum development;GO:0035904//aorta development;GO:0060976//coronary vasculature development	--
ENSG00000166848	37.382	37.764	38.168	37.041	37.886	37.81	1650	1677	1246	1212	1414	1216	TERF2IP	TERF2 interacting protein [Source:HGNC Symbol;Acc:HGNC:19246]	-	-	-	-	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0070187//shelterin complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0042162//telomeric DNA binding;GO:0098505//G-rich strand telomeric DNA binding	"GO:0000723//telomere maintenance;GO:0001933//negative regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0007004//telomere maintenance via telomerase;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010833//telomere maintenance via telomere lengthening;GO:0016233//telomere capping;GO:0031848//protection from non-homologous end joining at telomere;GO:0032204//regulation of telomere maintenance;GO:0032205//negative regulation of telomere maintenance;GO:0032206//positive regulation of telomere maintenance;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048239//negative regulation of DNA recombination at telomere;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060249//anatomical structure homeostasis;GO:0070198//protein localization to chromosome, telomeric region;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901985//positive regulation of protein acetylation"	--
ENSG00000166851	0.766	0.644	1.087	1.365	1.027	0.92	32	29	34	28	36	30	PLK1	polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077]	Cellular Processes;Environmental Information Processing;Cellular Processes;Organismal Systems	Cell growth and death;Signal transduction;Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K06631;K06631;K06631;K06631	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0000785//chromatin;GO:0000795//synaptonemal complex;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0034451//centriolar satellite;GO:0051233//spindle midzone;GO:0097431//mitotic spindle pole"	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0010997//anaphase-promoting complex binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0000070//mitotic sister chromatid segregation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000132//establishment of mitotic spindle orientation;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001578//microtubule bundle formation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007062//sister chromatid cohesion;GO:0007076//mitotic chromosome condensation;GO:0007077//mitotic nuclear membrane disassembly;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007098//centrosome cycle;GO:0007346//regulation of mitotic cell cycle;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0016310//phosphorylation;GO:0016321//female meiosis chromosome segregation;GO:0016567//protein ubiquitination;GO:0018105//peptidyl-serine phosphorylation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0031648//protein destabilization;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032465//regulation of cytokinesis;GO:0033365//protein localization to organelle;GO:0043066//negative regulation of apoptotic process;GO:0043393//regulation of protein binding;GO:0045143//homologous chromosome segregation;GO:0045184//establishment of protein localization;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045862//positive regulation of proteolysis;GO:0051081//nuclear membrane disassembly;GO:0051301//cell division;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0051726//regulation of cell cycle;GO:0070194//synaptonemal complex disassembly;GO:0071168//protein localization to chromatin;GO:0090435//protein localization to nuclear envelope;GO:1900182//positive regulation of protein localization to nucleus;GO:1901673//regulation of mitotic spindle assembly;GO:1901990//regulation of mitotic cell cycle phase transition;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:1904776//regulation of protein localization to cell cortex;GO:1905784//regulation of anaphase-promoting complex-dependent catabolic process	--
ENSG00000166855	8.999	9.341	7.865	6.524	7.677	7.531	762	778	531	398	522	465	CLPX	caseinolytic mitochondrial matrix peptidase chaperone subunit X [Source:HGNC Symbol;Acc:HGNC:2088]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0009368//endopeptidase Clp complex;GO:0009841//mitochondrial endopeptidase Clp complex;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0004176//ATP-dependent peptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016504//peptidase activator activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0006508//proteolysis;GO:0010952//positive regulation of peptidase activity;GO:0030163//protein catabolic process;GO:0046034//ATP metabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000166856	0.028	0.014	0	0	0	0	2	1	0	0	0	0	GPR182	G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000166860	2.7	2.479	3.208	3.074	2.831	3.33	351	324	308	296	311	315	ZBTB39	zinc finger and BTB domain containing 39 [Source:HGNC Symbol;Acc:HGNC:29014]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000166862	0	0	0	0	0	0	0	0	0	0	0	0	CACNG2	calcium voltage-gated channel auxiliary subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:1406]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04867;K04867;K04867;K04867;K04867;K04867;K04867	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0032281//AMPA glutamate receptor complex;GO:0036477//somatodendritic compartment;GO:0043005//neuron projection;GO:0044300//cerebellar mossy fiber;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0016247//channel regulator activity;GO:0035255//ionotropic glutamate receptor binding	"GO:0006612//protein targeting to membrane;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007528//neuromuscular junction development;GO:0019226//transmission of nerve impulse;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051592//response to calcium ion;GO:0051899//membrane depolarization;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060081//membrane hyperpolarization;GO:0060082//eye blink reflex;GO:0070588//calcium ion transmembrane transport;GO:0098943//neurotransmitter receptor transport, postsynaptic endosome to lysosome;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:0099590//neurotransmitter receptor internalization;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1904510//positive regulation of protein localization to basolateral plasma membrane;GO:2000311//regulation of AMPA receptor activity;GO:2000969//positive regulation of AMPA receptor activity"	--
ENSG00000166863	0	0	0	0	0	0	0	0	0	0	0	0	TAC3	tachykinin precursor 3 [Source:HGNC Symbol;Acc:HGNC:11521]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05240	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007217//tachykinin receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007565//female pregnancy;GO:0045777//positive regulation of blood pressure	--
ENSG00000166866	0	0	0	0	0	0	0	0	0	0	0	0	MYO1A	myosin IA [Source:HGNC Symbol;Acc:HGNC:7595]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0015629//actin cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0016459//myosin complex;GO:0030864//cortical actin cytoskeleton;GO:0031941//filamentous actin;GO:0031982//vesicle;GO:0044853//plasma membrane raft	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007605//sensory perception of sound;GO:0030030//cell projection organization;GO:0030033//microvillus assembly;GO:0030050//vesicle transport along actin filament;GO:0051648//vesicle localization	--
ENSG00000166869	0	0.024	0.066	0	0	0	0	1	2	0	0	0	CHP2	calcineurin like EF-hand protein 2 [Source:HGNC Symbol;Acc:HGNC:24927]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008284//positive regulation of cell population proliferation;GO:0010922//positive regulation of phosphatase activity;GO:0015031//protein transport;GO:0042307//positive regulation of protein import into nucleus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071277//cellular response to calcium ion	--
ENSG00000166881	3.335	3.189	3.924	3.295	3.28	3.673	385	372	305	269	322	310	NEMP1	nuclear envelope integral membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29001]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0071763//nuclear membrane organization	--
ENSG00000166884	0	0	0	0	0	0	0	0	0	0	0	0	OR4D6	olfactory receptor family 4 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:15175]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000166886	7.1	6.901	8.035	8.293	8.039	8.103	366	358	306	316	348	303	NAB2	NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0001958//endochondral ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0014037//Schwann cell differentiation;GO:0016480//negative regulation of transcription by RNA polymerase III;GO:0042552//myelination;GO:0045682//regulation of epidermis development;GO:0045892//negative regulation of transcription, DNA-templated;GO:1902949//positive regulation of tau-protein kinase activity"	--
ENSG00000166887	23.689	24.956	23.142	22.656	24.231	23.775	2322	2466	1713	1655	1960	1701	VPS39	VPS39 subunit of HOPS complex [Source:HGNC Symbol;Acc:HGNC:20593]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20183	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030897//HOPS complex;GO:0031902//late endosome membrane;GO:1902501//lysosomal HOPS complex	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032456//endocytic recycling;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly;GO:0046907//intracellular transport;GO:0061909//autophagosome-lysosome fusion;GO:1902774//late endosome to lysosome transport	--
ENSG00000166888	8.783	10.494	10.914	10.367	9.574	12.122	684	694	582	609	645	641	STAT6	signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Cell growth and death;Infectious disease: viral;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko04659//Th17 cell differentiation;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K11225;K11225;K11225;K11225;K11225;K11225;K11225	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002296//T-helper 1 cell lineage commitment;GO:0002829//negative regulation of type 2 immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0010467//gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:0034097//response to cytokine;GO:0035771//interleukin-4-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0060443//mammary gland morphogenesis;GO:0070301//cellular response to hydrogen peroxide;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902170//cellular response to reactive nitrogen species"	STAT
ENSG00000166889	18.005	17.727	18.133	20.003	18.658	22.322	1542	1526	1147	1269	1350	1391	PATL1	"PAT1 homolog 1, processing body mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:26721]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12617	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0030014//CCR4-NOT complex;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0034046//poly(G) binding	GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0033962//P-body assembly	--
ENSG00000166896	0.396	0.891	1.378	1.559	0.564	0.553	13	28	26	20	31	23	ATP23	ATP23 metallopeptidase and ATP synthase assembly factor homolog [Source:HGNC Symbol;Acc:HGNC:29452]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0030054//cell junction;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004222//metalloendopeptidase activity;GO:0004677//DNA-dependent protein kinase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006468//protein phosphorylation;GO:0006508//proteolysis;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0034982//mitochondrial protein processing	--
ENSG00000166897	0.04	0.052	0.047	0.132	0.082	0.135	7	9	6	17	12	17	ELFN2	extracellular leucine rich repeat and fibronectin type III domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29396]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity	--
ENSG00000166900	13.153	13.29	14.196	13.373	13.445	15.368	804	810	624	626	680	715	STX3	syntaxin 3 [Source:HGNC Symbol;Acc:HGNC:11438]	Organismal Systems;Genetic Information Processing	"Nervous system;Folding, sorting and degradation"	ko04721//Synaptic vesicle cycle;ko04130//SNARE interactions in vesicular transport	K08486;K08486	GO:0005773//vacuole;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031201//SNARE complex;GO:0042470//melanosome;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0042589//zymogen granule membrane;GO:0043005//neuron projection;GO:0048787//presynaptic active zone membrane;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0050544//arachidonic acid binding	GO:0006836//neurotransmitter transport;GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0008284//positive regulation of cell population proliferation;GO:0016192//vesicle-mediated transport;GO:0031175//neuron projection development;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0045785//positive regulation of cell adhesion;GO:0048278//vesicle docking;GO:0050921//positive regulation of chemotaxis;GO:0060291//long-term synaptic potentiation;GO:0061025//membrane fusion;GO:0098967//exocytic insertion of neurotransmitter receptor to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000166902	23.905	27.769	29.879	34.136	28.769	30.102	537	627	488	568	546	492	MRPL16	mitochondrial ribosomal protein L16 [Source:HGNC Symbol;Acc:HGNC:14476]	Genetic Information Processing	Translation	ko03010//Ribosome	K02878	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000166908	23.308	20.795	25.787	19.912	22.382	23.813	1331	1321	1023	962	1180	1060	PIP4K2C	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma [Source:HGNC Symbol;Acc:HGNC:23786]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Cell motility;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04810//Regulation of actin cytoskeleton;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00920;K00920;K00920;K00920	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding	"GO:0006629//lipid metabolic process;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0090217//negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:1902635//1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process;GO:2000786//positive regulation of autophagosome assembly"	--
ENSG00000166912	7.985	7.085	7.977	6.701	7.4	9.72	758.99	689.48	589.63	463.52	594.08	597.89	MTMR10	myotubularin related protein 10 [Source:HGNC Symbol;Acc:HGNC:25999]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004438//phosphatidylinositol-3-phosphatase activity	GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000166913	60.526	62.646	57.776	52.65	55.145	55.75	3761	3898	2673	2423	2873	2538	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [Source:HGNC Symbol;Acc:HGNC:12849]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle	K16197;K16197;K16197;K16197;K16197;K16197;K16197	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0045296//cadherin binding;GO:0050815//phosphoserine residue binding;GO:0051219//phosphoprotein binding	GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0034613//cellular protein localization;GO:0035308//negative regulation of protein dephosphorylation;GO:0043085//positive regulation of catalytic activity;GO:0043086//negative regulation of catalytic activity;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0051220//cytoplasmic sequestering of protein;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	--
ENSG00000166920	0	0	0	0	0.088	0.204	0	0	0	0	1	2	C15orf48	chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898]	-	-	-	-	GO:0005634//nucleus;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0009617//response to bacterium	--
ENSG00000166922	513.635	549.18	520.135	351.966	379.029	461.107	12817.51	13734.3	9564.66	6529.36	8009.42	8419.91	SCG5	secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0030141//secretory granule	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0030234//enzyme regulator activity;GO:0051082//unfolded protein binding	GO:0006886//intracellular protein transport;GO:0007218//neuropeptide signaling pathway;GO:0016486//peptide hormone processing;GO:0043086//negative regulation of catalytic activity;GO:0046883//regulation of hormone secretion;GO:0050790//regulation of catalytic activity	--
ENSG00000166923	26.515	26.08	12.082	37.847	35.451	29.122	2233	2216	778	2342	2574	1821	GREM1	"gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001]"	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K23318	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0016015//morphogen activity;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0036122//BMP binding;GO:0042803//protein homodimerization activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0048018//receptor ligand activity	"GO:0000902//cell morphogenesis;GO:0001525//angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0002092//positive regulation of receptor internalization;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0009954//proximal/distal pattern formation;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0030199//collagen fibril organization;GO:0030308//negative regulation of cell growth;GO:0030326//embryonic limb morphogenesis;GO:0030502//negative regulation of bone mineralization;GO:0030514//negative regulation of BMP signaling pathway;GO:0032331//negative regulation of chondrocyte differentiation;GO:0033689//negative regulation of osteoblast proliferation;GO:0038098//sequestering of BMP from receptor via BMP binding;GO:0043066//negative regulation of apoptotic process;GO:0043542//endothelial cell migration;GO:0045668//negative regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046851//negative regulation of bone remodeling;GO:0048263//determination of dorsal identity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051893//regulation of focal adhesion assembly;GO:0051973//positive regulation of telomerase activity;GO:0060173//limb development;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060676//ureteric bud formation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090027//negative regulation of monocyte chemotaxis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090291//negative regulation of osteoclast proliferation;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:1900155//negative regulation of bone trabecula formation;GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000273//positive regulation of signaling receptor activity;GO:2000727//positive regulation of cardiac muscle cell differentiation"	--
ENSG00000166924	1.77	1.42	2.109	1.199	1.452	2.23	129	101	107	66	86	109	NYAP1	neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 [Source:HGNC Symbol;Acc:HGNC:22009]	-	-	-	-	-	-	GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0048812//neuron projection morphogenesis	--
ENSG00000166925	143.144	151.249	143.18	141.12	153.665	127.657	2737	2890	2052	2261	2614	1948	TSC22D4	TSC22 domain family member 4 [Source:HGNC Symbol;Acc:HGNC:21696]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006970//response to osmotic stress;GO:0045892//negative regulation of transcription, DNA-templated"	TSC22
ENSG00000166926	0	0	0	0	0	0	0	0	0	0	0	0	MS4A6E	membrane spanning 4-domains A6E [Source:HGNC Symbol;Acc:HGNC:14285]	-	-	-	-	GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000166927	0	0	0	0	0.102	0	0	0	0	0	4	0	MS4A7	membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378]	-	-	-	-	GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000166928	0	0	0	0	0	0	0	0	0	0	0	0	MS4A14	membrane spanning 4-domains A14 [Source:HGNC Symbol;Acc:HGNC:30706]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000166930	0	0	0	0	0	0	0	0	0	0	0	0	MS4A5	membrane spanning 4-domains A5 [Source:HGNC Symbol;Acc:HGNC:13374]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000166938	12.393	12.838	12.704	11.695	11.551	12.607	914	925	670	604	699	692	DIS3L	DIS3 like exosome 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:28698]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K18681	GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding	"GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000166946	23.964	23.938	24.916	21.529	22.682	24.31	799	809	607	548	649	604	CCNDBP1	cyclin D1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1587]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051726//regulation of cell cycle	--
ENSG00000166947	0	0	0	0	0	0	0	0	0	0	0	0	EPB42	erythrocyte membrane protein band 4.2 [Source:HGNC Symbol;Acc:HGNC:3381]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030863//cortical cytoskeleton	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0000902//cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0018149//peptide cross-linking;GO:0020027//hemoglobin metabolic process;GO:0043249//erythrocyte maturation;GO:0048536//spleen development;GO:0050801//ion homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000166948	0	0	0	0	0	0	0	0	0	0	0	0	TGM6	transglutaminase 6 [Source:HGNC Symbol;Acc:HGNC:16255]	-	-	-	-	GO:0005737//cytoplasm	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding	GO:0018149//peptide cross-linking	--
ENSG00000166949	22.865	23.619	26.181	28.94	30.986	33.007	2304	2316	2003	2201	2224	2196	SMAD3	SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Signal transduction;Cancer: specific types;Infectious disease: viral;Cell growth and death;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Signal transduction;Cell growth and death;Immune system;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Immune disease	ko05200//Pathways in cancer;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04659//Th17 cell differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko04520//Adherens junction;ko05321//Inflammatory bowel disease	K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605;K23605	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0071141//SMAD protein complex;GO:0071144//heteromeric SMAD protein complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001217//DNA-binding transcription repressor activity;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0016922//nuclear receptor binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0031962//mineralocorticoid receptor binding;GO:0032810//sterol response element binding;GO:0035259//glucocorticoid receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043130//ubiquitin binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070410//co-SMAD binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding;GO:0140297//DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001657//ureteric bud development;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0001756//somitogenesis;GO:0001889//liver development;GO:0001947//heart looping;GO:0002076//osteoblast development;GO:0002520//immune system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006955//immune response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007183//SMAD protein complex assembly;GO:0007254//JNK cascade;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0009880//embryonic pattern specification;GO:0010628//positive regulation of gene expression;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0016202//regulation of striated muscle tissue development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030878//thyroid gland development;GO:0031053//primary miRNA processing;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032909//regulation of transforming growth factor beta2 production;GO:0032916//positive regulation of transforming growth factor beta3 production;GO:0032924//activin receptor signaling pathway;GO:0033689//negative regulation of osteoblast proliferation;GO:0038092//nodal signaling pathway;GO:0042060//wound healing;GO:0042110//T cell activation;GO:0042177//negative regulation of protein catabolic process;GO:0042307//positive regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0045216//cell-cell junction organization;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045599//negative regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048340//paraxial mesoderm morphogenesis;GO:0048589//developmental growth;GO:0048617//embryonic foregut morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050678//regulation of epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0050776//regulation of immune response;GO:0050821//protein stabilization;GO:0050927//positive regulation of positive chemotaxis;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051098//regulation of binding;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0060039//pericardium development;GO:0060290//transdifferentiation;GO:0060395//SMAD protein signal transduction;GO:0061045//negative regulation of wound healing;GO:0061767//negative regulation of lung blood pressure;GO:0070306//lens fiber cell differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090287//regulation of cellular response to growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:1901203//positive regulation of extracellular matrix assembly;GO:1902893//regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress"	MH1
ENSG00000166959	0	0	0	0	0	0	0	0	0	0	0	0	MS4A8	membrane spanning 4-domains A8 [Source:HGNC Symbol;Acc:HGNC:13380]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000166960	0.095	0	0.064	0	0	0	2	0	1	0	0	0	CCDC178	coiled-coil domain containing 178 [Source:HGNC Symbol;Acc:HGNC:29588]	-	-	-	-	GO:0036064//ciliary basal body	-	-	--
ENSG00000166961	0	0	0	0	0	0	0	0	0	0	0	0	MS4A15	membrane spanning 4-domains A15 [Source:HGNC Symbol;Acc:HGNC:28573]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000166963	6.447	6.608	5.751	5.119	5.243	4.808	1375	1420	909	812	944	747	MAP1A	microtubule associated protein 1A [Source:HGNC Symbol;Acc:HGNC:6835]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0030424//axon;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043198//dendritic shaft;GO:0044307//dendritic branch;GO:0045202//synapse;GO:0150001//primary dendrite;GO:1901588//dendritic microtubule;GO:1904115//axon cytoplasm	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal anchor activity;GO:0015631//tubulin binding;GO:0048156//tau protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0007409//axonogenesis;GO:0007613//memory;GO:0008306//associative learning;GO:0016358//dendrite development;GO:0031114//regulation of microtubule depolymerization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048167//regulation of synaptic plasticity;GO:0050882//voluntary musculoskeletal movement;GO:0070050//neuron cellular homeostasis;GO:0099641//anterograde axonal protein transport;GO:0099642//retrograde axonal protein transport;GO:1902817//negative regulation of protein localization to microtubule;GO:1903829//positive regulation of cellular protein localization;GO:1990535//neuron projection maintenance;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000166965	9.984	11.32	9.255	11.569	11.075	11.178	543	512	366	472	472	430	RCCD1	RCC1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30457]	-	-	-	-	GO:0005694//chromosome;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0006325//chromatin organization	--
ENSG00000166971	18.032	19.126	17.492	15.46	15.521	18.203	712.62	678.4	516.18	422.95	477.55	531.03	AKTIP	AKT interacting protein [Source:HGNC Symbol;Acc:HGNC:16710]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030897//HOPS complex;GO:0070695//FHF complex	GO:0005515//protein binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0001934//positive regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0032092//positive regulation of protein binding;GO:0045022//early endosome to late endosome transport;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000166974	10	9.525	7.573	7.941	8.854	9.941	667	671	449	434	601	561	MAPRE2	microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end;GO:0051233//spindle midzone	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0051010//microtubule plus-end binding	GO:0007049//cell cycle;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0032014//positive regulation of ARF protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0051549//positive regulation of keratinocyte migration;GO:0120183//positive regulation of focal adhesion disassembly;GO:1904825//protein localization to microtubule plus-end	--
ENSG00000166979	0.476	0.26	0.201	0.273	0.29	0.128	13	9	5	7	8	3	EVA1C	eva-1 homolog C [Source:HGNC Symbol;Acc:HGNC:13239]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008201//heparin binding;GO:0030246//carbohydrate binding	GO:0008150//biological_process	--
ENSG00000166984	0	0	0	0	0	0	0	0	0	0	0	0	TCP10L2	"t-complex 10 like 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:21254]"	-	-	-	-	-	-	-	--
ENSG00000166986	39.567	31.814	71.739	37.004	68.658	63.594	1783	1860	1383	1444.5	1450	1737	MARS1	methionyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6898]	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00450//Selenocompound metabolism	K01874;K01874;K01874	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004825//methionine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006431//methionyl-tRNA aminoacylation;GO:0009267//cellular response to starvation;GO:0009303//rRNA transcription;GO:0032869//cellular response to insulin stimulus;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0044238//primary metabolic process;GO:0071364//cellular response to epidermal growth factor stimulus;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	--
ENSG00000166987	5.627	6.491	6.123	7.847	6.111	6.679	375	397	359	374	380	399	MBD6	methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:HGNC:20445]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0010369//chromocenter	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	-	--
ENSG00000166997	21.109	21.652	24.703	18.692	15.923	17.998	640.97	659.96	553	413	406	400	CNPY4	canopy FGF signaling regulator 4 [Source:HGNC Symbol;Acc:HGNC:28631]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000167004	295.984	313.943	269.803	274.043	281.17	264.586	11936.58	12705.62	8040.58	8148.34	9244.17	7553.47	PDIA3	protein disulfide isomerase family A member 3 [Source:HGNC Symbol;Acc:HGNC:4606]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Organismal Systems	"Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Folding, sorting and degradation;Immune system"	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko04141//Protein processing in endoplasmic reticulum;ko04612//Antigen processing and presentation	K08056;K08056;K08056;K08056;K08056;K08056	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0042470//melanosome;GO:0042824//MHC class I peptide loading complex;GO:0045335//phagocytic vesicle;GO:0055038//recycling endosome membrane;GO:0061779//Tapasin-ERp57 complex;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003756//protein disulfide isomerase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0015036//disulfide oxidoreductase activity;GO:0016853//isomerase activity;GO:0042802//identical protein binding	GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0006457//protein folding;GO:0006508//proteolysis;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0098761//cellular response to interleukin-7;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000167005	18.986	16.804	17.98	18.179	20.495	19.965	1730	1539	1210	1227	1396	1270	NUDT21	nudix hydrolase 21 [Source:HGNC Symbol;Acc:HGNC:13870]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14397	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005849//mRNA cleavage factor complex;GO:0016604//nuclear body;GO:0034451//centriolar satellite;GO:0042382//paraspeckles	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0010608//posttranscriptional regulation of gene expression;GO:0030154//cell differentiation;GO:0031124//mRNA 3'-end processing;GO:0031439//positive regulation of mRNA cleavage;GO:0051262//protein tetramerization;GO:0051290//protein heterotetramerization;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0110104//mRNA alternative polyadenylation;GO:1900365//positive regulation of mRNA polyadenylation;GO:1990120//messenger ribonucleoprotein complex assembly;GO:2000738//positive regulation of stem cell differentiation;GO:2000975//positive regulation of pro-B cell differentiation	--
ENSG00000167011	0	0	0	0	0	0	0	0	0	0	0	0	NAT16	N-acetyltransferase 16 (putative) [Source:HGNC Symbol;Acc:HGNC:22030]	-	-	-	-	-	"GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups"	-	--
ENSG00000167014	0	0	0	0	0	0	0	0	0	0	0	0	TERB2	telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005694//chromosome;GO:0016020//membrane"	GO:0005515//protein binding	GO:0007129//homologous chromosome pairing at meiosis;GO:0045141//meiotic telomere clustering;GO:0070197//meiotic attachment of telomere to nuclear envelope	--
ENSG00000167034	0.529	1.045	0.709	0.737	0.453	0.689	36	34	27	20	26	19	NKX3-1	NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05215//Prostate cancer	K09348;K09348	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0090734//site of DNA damage	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0030331//estrogen receptor binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0043621//protein self-association;GO:0097162//MADS box domain binding;GO:0140297//DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001655//urogenital system development;GO:0001656//metanephros development;GO:0001756//somitogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007431//salivary gland development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030154//cell differentiation;GO:0030521//androgen receptor signaling pathway;GO:0030850//prostate gland development;GO:0032880//regulation of protein localization;GO:0033574//response to testosterone;GO:0035907//dorsal aorta development;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043491//protein kinase B signaling;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051781//positive regulation of cell division;GO:0060037//pharyngeal system development;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071383//cellular response to steroid hormone stimulus;GO:0071456//cellular response to hypoxia;GO:0071466//cellular response to xenobiotic stimulus;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:2000836//positive regulation of androgen secretion;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2001235//positive regulation of apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	Homeobox
ENSG00000167037	0.011	0.107	0.045	0.075	0.053	0.107	1	15	3	5	4	7	SGSM1	small G protein signaling modulator 1 [Source:HGNC Symbol;Acc:HGNC:29410]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000167065	3.431	3.333	2.487	2.436	2.604	2.777	139	145	94.39	90	108	100	DUSP18	dual specificity phosphatase 18 [Source:HGNC Symbol;Acc:HGNC:18484]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation	--
ENSG00000167074	10.591	9.673	14.847	15.826	13.33	14.842	963	884	997	1066	1024	982	TEF	"TEF transcription factor, PAR bZIP family member [Source:HGNC Symbol;Acc:HGNC:11722]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process"	TF_bZIP
ENSG00000167077	0	0	0	0	0.014	0	0	0	0	0	1	0	MEI1	meiotic double-stranded break formation protein 1 [Source:HGNC Symbol;Acc:HGNC:28613]	-	-	-	-	-	-	GO:0007127//meiosis I;GO:0051321//meiotic cell cycle	--
ENSG00000167080	0	0.011	0	0	0.02	0	0	2	0	0	3	0	B4GALNT2	"beta-1,4-N-acetyl-galactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:24136]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006486//protein glycosylation;GO:0009312//oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019276//UDP-N-acetylgalactosamine metabolic process;GO:0022408//negative regulation of cell-cell adhesion;GO:0030259//lipid glycosylation	--
ENSG00000167081	54.762	52.032	45.502	39.672	45.49	50.058	2901	2599	1735	1608	1928	1755	PBX3	PBX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:8634]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15610	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001654//eye development;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007387//anterior compartment pattern formation;GO:0007388//posterior compartment specification;GO:0007420//brain development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008344//adult locomotory behavior;GO:0009887//animal organ morphogenesis;GO:0021516//dorsal spinal cord development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048666//neuron development"	Homeobox
ENSG00000167083	0	0	0	0	0	0	0	0	0	0	0	0	GNGT2	G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549;K04549	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007602//phototransduction	--
ENSG00000167085	62.553	67.973	70.417	78.58	74.524	77.372	2371	2593	1980	2209	2391	2144	PHB	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0035632//mitochondrial prohibitin complex;GO:0070062//extracellular exosome	GO:0001850//complement component C3a binding;GO:0001851//complement component C3b binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0031871//proteinase activated receptor binding;GO:0042826//histone deacetylase binding;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0002639//positive regulation of immunoglobulin production;GO:0006355//regulation of transcription, DNA-templated;GO:0007005//mitochondrion organization;GO:0007165//signal transduction;GO:0007202//activation of phospholipase C activity;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0016575//histone deacetylation;GO:0023035//CD40 signaling pathway;GO:0030308//negative regulation of cell growth;GO:0032740//positive regulation of interleukin-17 production;GO:0039529//RIG-I signaling pathway;GO:0042113//B cell activation;GO:0042177//negative regulation of protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0044830//modulation by host of viral RNA genome replication;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045917//positive regulation of complement activation;GO:0046718//viral entry into host cell;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050821//protein stabilization;GO:0050847//progesterone receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071354//cellular response to interleukin-6;GO:0071897//DNA biosynthetic process;GO:0072538//T-helper 17 type immune response;GO:0140374//antiviral innate immune response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1990051//activation of protein kinase C activity;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway"	Others
ENSG00000167088	6.349	10.499	7.255	6.85	5.234	8.108	378	372	324	306	299	299	SNRPD1	small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158]	Human Diseases;Genetic Information Processing	Immune disease;Transcription	ko05322//Systemic lupus erythematosus;ko03040//Spliceosome	K11087;K11087	GO:0000243//commitment complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0097526//spliceosomal tri-snRNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:1990446//U1 snRNP binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000167094	0.017	0	0	0	0.04	0.023	1	0	0	0	2	1	TTC16	tetratricopeptide repeat domain 16 [Source:HGNC Symbol;Acc:HGNC:26536]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000167098	0	0	0	0	0	0	0	0	0	0	0	0	SUN5	Sad1 and UNC84 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:16252]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex;GO:0097224//sperm connecting piece	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0043495//protein-membrane adaptor activity	GO:0006998//nuclear envelope organization;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation	--
ENSG00000167100	0.834	0.962	1.318	0.591	1.133	0.595	55.63	78.91	57.44	32.41	50.73	27.3	SAMD14	sterile alpha motif domain containing 14 [Source:HGNC Symbol;Acc:HGNC:27312]	-	-	-	-	GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030425//dendrite	GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0019722//calcium-mediated signaling;GO:0031175//neuron projection development	--
ENSG00000167103	0.894	0.554	0.518	0.299	0.55	0.632	24	15	11	10	14	12	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase like 1 [Source:HGNC Symbol;Acc:HGNC:28711]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04144//Endocytosis;ko00562//Inositol phosphate metabolism	K13712;K13712;K13712	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016740//transferase activity	GO:0001933//negative regulation of protein phosphorylation;GO:0006629//lipid metabolic process;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0016310//phosphorylation;GO:0030336//negative regulation of cell migration;GO:0043065//positive regulation of apoptotic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000167104	0	0	0	0	0	0	0	0	0	0	0	0	BPIFB6	BPI fold containing family B member 6 [Source:HGNC Symbol;Acc:HGNC:16504]	-	-	-	-	GO:0005576//extracellular region	GO:0008289//lipid binding	-	--
ENSG00000167105	0.179	0.107	0.048	0.073	0.191	0.123	10	6	2	3	9	5	TMEM92	transmembrane protein 92 [Source:HGNC Symbol;Acc:HGNC:26579]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000167106	32.879	31.503	35.348	54.14	49.402	51.404	2710	2626	2139	3247	3441	3125	FAM102A	family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000167107	9.486	10.707	10.225	10.881	13.476	11.22	417	452	341	316	410	346	ACSF2	acyl-CoA synthetase family member 2 [Source:HGNC Symbol;Acc:HGNC:26101]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0047760//butyrate-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000167110	25.396	27.566	32.925	24.931	23.351	31.249	1812	1830	1436	1364	1489	1520	GOLGA2	golgin A2 [Source:HGNC Symbol;Acc:HGNC:4425]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0019905//syntaxin binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0061676//importin-alpha family protein binding	GO:0006486//protein glycosylation;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007020//microtubule nucleation;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0008356//asymmetric cell division;GO:0010507//negative regulation of autophagy;GO:0015031//protein transport;GO:0032091//negative regulation of protein binding;GO:0051225//spindle assembly;GO:0051289//protein homotetramerization;GO:0051301//cell division;GO:0060050//positive regulation of protein glycosylation;GO:0090161//Golgi ribbon formation;GO:0090166//Golgi disassembly;GO:0090306//meiotic spindle assembly;GO:0090307//mitotic spindle assembly	--
ENSG00000167112	6.602	6.842	7.315	6.645	7.141	6.777	743	774	608	554	679	555	TRUB2	TruB pseudouridine synthase family member 2 [Source:HGNC Symbol;Acc:HGNC:17170]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity	GO:0001522//pseudouridine synthesis;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0009451//RNA modification;GO:0070131//positive regulation of mitochondrial translation;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000167113	22.851	24.068	25.127	28.778	24.568	22.207	544	588	440	511	501	378	COQ4	coenzyme Q4 [Source:HGNC Symbol;Acc:HGNC:19693]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0032991//protein-containing complex;GO:0110142//ubiquinone biosynthesis complex	GO:0005515//protein binding	GO:0006744//ubiquinone biosynthetic process	--
ENSG00000167114	11.96	13.711	15.162	16.468	15.375	14.775	801	923	750	817	870	720	SLC27A4	solute carrier family 27 member 4 [Source:HGNC Symbol;Acc:HGNC:10998]	Human Diseases;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine system;Digestive system	ko04931//Insulin resistance;ko03320//PPAR signaling pathway;ko04975//Fat digestion and absorption	K08745;K08745;K08745	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0015245//fatty acid transmembrane transporter activity;GO:0016874//ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0090433//palmitoyl-CoA ligase activity;GO:0090434//oleoyl-CoA ligase activity;GO:1901480//oleate transmembrane transporter activity	"GO:0000038//very long-chain fatty acid metabolic process;GO:0001579//medium-chain fatty acid transport;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006869//lipid transport;GO:0007584//response to nutrient;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0042760//very long-chain fatty acid catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043588//skin development;GO:0044381//glucose import in response to insulin stimulus;GO:0044539//long-chain fatty acid import into cell;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0062003//negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity;GO:0090630//activation of GTPase activity;GO:0150104//transport across blood-brain barrier;GO:1990379//lipid transport across blood-brain barrier"	--
ENSG00000167117	0	0	0	0	0	0	0	0	0	0	0	0	ANKRD40CL	ANKRD40 C-terminal like [Source:HGNC Symbol;Acc:HGNC:26080]	-	-	-	-	-	-	-	--
ENSG00000167118	23.602	27.468	30.63	35.582	32.632	32.91	742	873	632	760	828	693	URM1	ubiquitin related modifier 1 [Source:HGNC Symbol;Acc:HGNC:28378]	Genetic Information Processing	"Folding, sorting and degradation"	ko04122//Sulfur relay system	K12161	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031386//protein tag;GO:0097163//sulfur carrier activity	GO:0002098//tRNA wobble uridine modification;GO:0008033//tRNA processing;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification	--
ENSG00000167123	43.548	47.248	40.113	40.423	42.321	37.218	2053	2257	1389	1404	1669	1261	CERCAM	cerebral endothelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:23723]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion	--
ENSG00000167130	6.498	7.501	7.828	8.321	7.745	9.398	287	337	259	274	292	305	DOLPP1	dolichyldiphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:29565]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K07252;K07252	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0016787//hydrolase activity;GO:0047874//dolichyldiphosphatase activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0008610//lipid biosynthetic process;GO:0044238//primary metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000167131	1.996	2.65	2.581	0.53	0.833	4.202	85.35	148.82	83.43	6.68	12.85	136.01	CCDC103	coiled-coil domain containing 103 [Source:HGNC Symbol;Acc:HGNC:32700]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036157//outer dynein arm;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0001947//heart looping;GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007368//determination of left/right symmetry;GO:0030030//cell projection organization;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0070286//axonemal dynein complex assembly;GO:0071907//determination of digestive tract left/right asymmetry	--
ENSG00000167136	11.638	10.496	13.71	15.788	12.996	14.442	276.4	250.56	240.49	277.74	260.76	249.57	ENDOG	endonuclease G [Source:HGNC Symbol;Acc:HGNC:3346]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K01173	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0043204//perikaryon	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004521//endoribonuclease activity;GO:0004536//deoxyribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0001701//in utero embryonic development;GO:0006309//apoptotic DNA fragmentation;GO:0006310//DNA recombination;GO:0007568//aging;GO:0009612//response to mechanical stimulus;GO:0010508//positive regulation of autophagy;GO:0032007//negative regulation of TOR signaling;GO:0032043//mitochondrial DNA catabolic process;GO:0032355//response to estradiol;GO:0034599//cellular response to oxidative stress;GO:0034612//response to tumor necrosis factor;GO:0036475//neuron death in response to oxidative stress;GO:0043065//positive regulation of apoptotic process;GO:0046677//response to antibiotic;GO:0071277//cellular response to calcium ion;GO:0071333//cellular response to glucose stimulus;GO:0071456//cellular response to hypoxia;GO:0090297//positive regulation of mitochondrial DNA replication;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:1902512//positive regulation of apoptotic DNA fragmentation;GO:2001022//positive regulation of response to DNA damage stimulus"	--
ENSG00000167139	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D21	TBC1 domain family member 21 [Source:HGNC Symbol;Acc:HGNC:28536]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece	GO:0003779//actin binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0090630//activation of GTPase activity;GO:0120317//sperm mitochondrial sheath assembly	--
ENSG00000167157	0	0.037	0	0	0.087	0	0	1	0	0	2	0	PRRX2	paired related homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21338]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000167165	0	0.143	0	0	0	0.057	0	3.36	0	0	0	0.67	UGT1A6	UDP glucuronosyltransferase family 1 member A6 [Source:HGNC Symbol;Acc:HGNC:12538]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation	--
ENSG00000167173	1.874	1.753	2.939	2.242	2.182	1.683	168	150	145	141	164	110	C15orf39	chromosome 15 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:24497]	-	-	-	-	GO:0005829//cytosol	-	-	--
ENSG00000167178	0.339	1.244	0.241	0.594	0.266	0.099	14	31	5	10	5	6	ISLR2	immunoglobulin superfamily containing leucine rich repeat 2 [Source:HGNC Symbol;Acc:HGNC:29286]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0045773//positive regulation of axon extension	--
ENSG00000167182	7.893	9.714	9.297	8.222	8.932	9.256	408	384	347	309	350	283	SP2	Sp2 transcription factor [Source:HGNC Symbol;Acc:HGNC:11207]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006955//immune response;GO:0035264//multicellular organism growth	zf-C2H2
ENSG00000167183	0.032	0	0	0	0.037	0	1	0	0	0	1	0	PRR15L	proline rich 15 like [Source:HGNC Symbol;Acc:HGNC:28149]	-	-	-	-	-	-	-	--
ENSG00000167186	13.283	9.49	13.524	9.074	11.053	13.365	535	443	410	340	416	440	COQ7	"coenzyme Q7, hydroxylase [Source:HGNC Symbol;Acc:HGNC:2244]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K06134;K06134	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0110142//ubiquinone biosynthesis complex	"GO:0003682//chromatin binding;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0008682//2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006744//ubiquinone biosynthetic process;GO:0008340//determination of adult lifespan;GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000167191	12.422	11.287	11.152	13.889	12.798	14.218	942.93	913.74	597.44	777.58	802.58	804.84	GPRC5B	G protein-coupled receptor class C group 5 member B [Source:HGNC Symbol;Acc:HGNC:13308]	-	-	-	-	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0001664//G protein-coupled receptor binding;GO:0004930//G protein-coupled receptor activity;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032147//activation of protein kinase activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045666//positive regulation of neuron differentiation;GO:0050729//positive regulation of inflammatory response;GO:0060907//positive regulation of macrophage cytokine production;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000167193	21.842	19.334	21.38	17.993	20.543	22.915	1708	1515	1234	1043	1347	1301	CRK	"CRK proto-oncogene, adaptor protein [Source:HGNC Symbol;Acc:HGNC:2362]"	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cancer: overview;Immune system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04910//Insulin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04012//ErbB signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma"	K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438;K04438	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0001784//phosphotyrosine residue binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030674//protein-macromolecule adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding;GO:0043621//protein self-association;GO:0045309//protein phosphorylated amino acid binding;GO:0046875//ephrin receptor binding;GO:0097110//scaffold protein binding;GO:1990782//protein tyrosine kinase binding	GO:0001764//neuron migration;GO:0001878//response to yeast;GO:0002685//regulation of leukocyte migration;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0009966//regulation of signal transduction;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0030010//establishment of cell polarity;GO:0030036//actin cytoskeleton organization;GO:0030307//positive regulation of cell growth;GO:0032956//regulation of actin cytoskeleton organization;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0035020//regulation of Rac protein signal transduction;GO:0035685//helper T cell diapedesis;GO:0035728//response to hepatocyte growth factor;GO:0038026//reelin-mediated signaling pathway;GO:0042542//response to hydrogen peroxide;GO:0043087//regulation of GTPase activity;GO:0043393//regulation of protein binding;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0048013//ephrin receptor signaling pathway;GO:0050773//regulation of dendrite development;GO:0060326//cell chemotaxis;GO:0061045//negative regulation of wound healing;GO:0061847//response to cholecystokinin;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071732//cellular response to nitric oxide;GO:0090630//activation of GTPase activity;GO:0098749//cerebellar neuron development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901652//response to peptide;GO:1902531//regulation of intracellular signal transduction;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:1990859//cellular response to endothelin;GO:2000146//negative regulation of cell motility;GO:2000404//regulation of T cell migration	--
ENSG00000167194	0	0	0	0	0	0	0	0	0	0	0	0	C16orf92	chromosome 16 open reading frame 92 [Source:HGNC Symbol;Acc:HGNC:26346]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0009566//fertilization	--
ENSG00000167195	0.026	0	0	0.023	0	0	3	0	0	2	0	0	GOLGA6C	golgin A6 family member C [Source:HGNC Symbol;Acc:HGNC:32206]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	-	GO:0007030//Golgi organization	--
ENSG00000167196	10.197	8.071	8.073	6.996	6.823	8.239	407.91	334	222	216	235.91	270	FBXO22	F-box protein 22 [Source:HGNC Symbol;Acc:HGNC:13593]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K10302	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030018//Z disc	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006913//nucleocytoplasmic transport;GO:0009267//cellular response to starvation;GO:0010830//regulation of myotube differentiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048742//regulation of skeletal muscle fiber development;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000167202	33.007	33.551	33.684	31.598	33.469	35.185	4194	4285	3161	2974	3593	3218	TBC1D2B	TBC1 domain family member 2B [Source:HGNC Symbol;Acc:HGNC:29183]	-	-	-	-	GO:0005769//early endosome;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0090630//activation of GTPase activity	--
ENSG00000167207	0	0	0	0	0.024	0.036	0	0	0	0	2	3	NOD2	nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases	Infectious disease: bacterial;Immune system;Signal transduction;Immune disease	ko05152//Tuberculosis;ko04621//NOD-like receptor signaling pathway;ko04668//TNF signaling pathway;ko05321//Inflammatory bowel disease	K10165;K10165;K10165;K10165	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0045335//phagocytic vesicle;GO:0046658//anchored component of plasma membrane	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding;GO:0032500//muramyl dipeptide binding;GO:0038187//pattern recognition receptor activity;GO:0042834//peptidoglycan binding;GO:0044877//protein-containing complex binding;GO:0050700//CARD domain binding;GO:0051879//Hsp90 protein binding	GO:0002221//pattern recognition receptor signaling pathway;GO:0002227//innate immune response in mucosa;GO:0002253//activation of immune response;GO:0002376//immune system process;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0002710//negative regulation of T cell mediated immunity;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0002830//positive regulation of type 2 immune response;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006952//defense response;GO:0006963//positive regulation of antibacterial peptide biosynthetic process;GO:0006965//positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria;GO:0007584//response to nutrient;GO:0008284//positive regulation of cell population proliferation;GO:0009595//detection of biotic stimulus;GO:0016045//detection of bacterium;GO:0030277//maintenance of gastrointestinal epithelium;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032494//response to peptidoglycan;GO:0032495//response to muramyl dipeptide;GO:0032496//response to lipopolysaccharide;GO:0032498//detection of muramyl dipeptide;GO:0032689//negative regulation of interferon-gamma production;GO:0032695//negative regulation of interleukin-12 production;GO:0032701//negative regulation of interleukin-18 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032740//positive regulation of interleukin-17 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0045747//positive regulation of Notch signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046645//positive regulation of gamma-delta T cell activation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050727//regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766//positive regulation of phagocytosis;GO:0050830//defense response to Gram-positive bacterium;GO:0050871//positive regulation of B cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051353//positive regulation of oxidoreductase activity;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071224//cellular response to peptidoglycan;GO:0071225//cellular response to muramyl dipeptide;GO:0071407//cellular response to organic cyclic compound;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0090022//regulation of neutrophil chemotaxis;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1904417//positive regulation of xenophagy;GO:2000110//negative regulation of macrophage apoptotic process;GO:2000363//positive regulation of prostaglandin-E synthase activity	--
ENSG00000167208	0	0	0	0	0.049	0	0	0	0	0	2	0	SNX20	sorting nexin 20 [Source:HGNC Symbol;Acc:HGNC:30390]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:1901981//phosphatidylinositol phosphate binding"	GO:0015031//protein transport	--
ENSG00000167210	0	0	0	0	0	0	0	0	0	0	0	0	LOXHD1	lipoxygenase homology PLAT domains 1 [Source:HGNC Symbol;Acc:HGNC:26521]	-	-	-	-	GO:0032420//stereocilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007605//sensory perception of sound	--
ENSG00000167216	5.46	4.199	5.269	2.956	3.348	4.593	233	210	163	132	153	171	KATNAL2	katanin catalytic subunit A1 like 2 [Source:HGNC Symbol;Acc:HGNC:25387]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008568//microtubule-severing ATPase activity;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity	GO:0051013//microtubule severing	--
ENSG00000167220	16.16	15.429	16.695	14.606	15.422	15.837	690	607.05	548	476	557	510	HDHD2	haloacid dehalogenase like hydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25364]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0016311//dephosphorylation	--
ENSG00000167232	5.342	2.592	2.779	2.069	2.625	3.279	459.38	267	168	139	226	199.34	ZNF91	zinc finger protein 91 [Source:HGNC Symbol;Acc:HGNC:13166]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070895//negative regulation of transposon integration"	zf-C2H2
ENSG00000167244	8.628	10.302	7.93	13.784	13.401	8.17	815	986	562	957	1065	558	IGF2	insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05205//Proteoglycans in cancer;ko05225//Hepatocellular carcinoma	K13769;K13769;K13769;K13769;K13769;K13769	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen	GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005178//integrin binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0048018//receptor ligand activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001892//embryonic placenta development;GO:0001934//positive regulation of protein phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0031017//exocrine pancreas development;GO:0031056//regulation of histone modification;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0040018//positive regulation of multicellular organism growth;GO:0042104//positive regulation of activated T cell proliferation;GO:0043085//positive regulation of catalytic activity;GO:0043410//positive regulation of MAPK cascade;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046622//positive regulation of organ growth;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051146//striated muscle cell differentiation;GO:0051147//regulation of muscle cell differentiation;GO:0051148//negative regulation of muscle cell differentiation;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:0060669//embryonic placenta morphogenesis;GO:0060720//spongiotrophoblast cell proliferation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000467//positive regulation of glycogen (starch) synthase activity"	--
ENSG00000167257	6.573	6.156	6.2	5.662	8.785	7.244	370.4	359.11	274.41	239.08	321.67	258.05	RNF214	ring finger protein 214 [Source:HGNC Symbol;Acc:HGNC:25335]	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000167258	9.654	8.641	8.658	6.445	9.481	8.227	1285	1143	830	628	949	775	CDK12	cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0002944//cyclin K-CDK12 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008024//cyclin/CDK positive transcription elongation factor complex;GO:0016607//nuclear speck;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030332//cyclin binding;GO:0106310//protein serine kinase activity	GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0016310//phosphorylation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0043405//regulation of MAP kinase activity;GO:0043484//regulation of RNA splicing;GO:0046777//protein autophosphorylation;GO:0051726//regulation of cell cycle;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:2000737//negative regulation of stem cell differentiation	--
ENSG00000167261	0	0	0	0	0	0	0	0	0	0	0	0	DPEP2	dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]	-	-	-	-	GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process	--
ENSG00000167264	6.645	5.161	5.844	6.304	6.153	5.267	191	211	172	170	200	157	DUS2	dihydrouridine synthase 2 [Source:HGNC Symbol;Acc:HGNC:26014]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003824//catalytic activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070402//NADPH binding;GO:0102264//tRNA-dihydrouridine20 synthase activity	GO:0002943//tRNA dihydrouridine synthesis;GO:0008033//tRNA processing;GO:0043086//negative regulation of catalytic activity;GO:0060548//negative regulation of cell death	--
ENSG00000167272	8.107	7.853	9.736	7.95	8.187	6.496	180	174	159	130	155	106	POP5	"POP5 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:17689]"	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K03537	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030677//ribonuclease P complex;GO:0030681//multimeric ribonuclease P complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000167280	3.443	2.904	3.915	4.811	4.535	4.236	323	279	263	268	307	269	ENGASE	endo-beta-N-acetylglucosaminidase [Source:HGNC Symbol;Acc:HGNC:24622]	Metabolism	Glycan biosynthesis and metabolism	ko00511//Other glycan degradation	K01227	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0033925//mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"	GO:0006457//protein folding;GO:0006517//protein deglycosylation;GO:0008152//metabolic process	--
ENSG00000167281	0	0.046	0	0	0.054	0.027	0	2	0	0	3	1	RBFOX3	RNA binding fox-1 homolog 3 [Source:HGNC Symbol;Acc:HGNC:27097]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing"	--
ENSG00000167283	106.158	99.767	108.18	125.514	100.53	111.686	2445	2321.88	1850.73	2125	1989	1899	ATP5MG	ATP synthase membrane subunit g [Source:HGNC Symbol;Acc:HGNC:14247]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02140;K02140;K02140	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000167286	0	0	0	0	0	0	0	0	0	0	0	0	CD3D	CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview	ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04640//Hematopoietic cell lineage;ko05162//Measles;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06450;K06450;K06450;K06450;K06450;K06450;K06450;K06450;K06450;K06450;K06450	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0045059//positive thymic T cell selection;GO:0046631//alpha-beta T cell activation;GO:0050852//T cell receptor signaling pathway	--
ENSG00000167291	9.531	9.952	10.024	9.88	11.41	11.812	1608	1552	1160	1190	1359	1157	TBC1D16	TBC1 domain family member 16 [Source:HGNC Symbol;Acc:HGNC:28356]	-	-	-	-	GO:0005769//early endosome;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0001919//regulation of receptor recycling;GO:0090630//activation of GTPase activity	--
ENSG00000167302	3.96	3.235	4.596	3.255	3.92	5.679	134	138	133	100	133	154	TEPSIN	TEPSIN adaptor related protein complex 4 accessory protein [Source:HGNC Symbol;Acc:HGNC:26458]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030124//AP-4 adaptor complex;GO:0030662//coated vesicle membrane;GO:0031312//extrinsic component of organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	-	--
ENSG00000167306	10.61	11.418	9.351	10.471	11.145	10.532	1375	1350	868	919	1063	969	MYO5B	myosin VB [Source:HGNC Symbol;Acc:HGNC:7603]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10357	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0045179//apical cortex;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding	GO:0003091//renal water homeostasis;GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0030050//vesicle transport along actin filament	--
ENSG00000167311	1.687	1.328	1.721	1.24	0.979	1.457	43	34	32	23	21	27	ART5	ADP-ribosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:24049]	-	-	-	-	GO:0005576//extracellular region	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106274//NAD+-protein-arginine ADP-ribosyltransferase activity;GO:0106275//NADP+-protein-arginine ADP-ribosyltransferase activity	GO:0006471//protein ADP-ribosylation;GO:0018120//peptidyl-arginine ADP-ribosylation	--
ENSG00000167315	34.981	37.532	40.396	39.082	35.62	40.013	1226	1307	1081	1028	1092	1062	ACAA2	acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Lipid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation;ko00062//Fatty acid elongation"	K07508;K07508;K07508;K07508;K07508	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003723//RNA binding;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003986//acetyl-CoA hydrolase activity;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0016787//hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006695//cholesterol biosynthetic process;GO:0071456//cellular response to hypoxia;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process	--
ENSG00000167323	43.018	42.281	46.568	40.961	42.405	45.963	3378	3447	2854	2558	2874	2427	STIM1	stromal interaction molecule 1 [Source:HGNC Symbol;Acc:HGNC:11386]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04020//Calcium signaling pathway;ko04611//Platelet activation	K16059;K16059	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032541//cortical endoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0043229//intracellular organelle;GO:0044853//plasma membrane raft	GO:0002020//protease binding;GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051010//microtubule plus-end binding	GO:0002115//store-operated calcium entry;GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0032237//activation of store-operated calcium channel activity;GO:0045762//positive regulation of adenylate cyclase activity;GO:0045766//positive regulation of angiogenesis;GO:0051924//regulation of calcium ion transport;GO:0070166//enamel mineralization;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000167325	17.22	17.556	15.4	11.725	11.999	11.894	1101	1150	724	566	660	564	RRM1	ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00480//Glutathione metabolism;ko00240//Pyrimidine metabolism	K10807;K10807;K10807;K10807;K10807	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005971//ribonucleoside-diphosphate reductase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016491//oxidoreductase activity;GO:0017076//purine nucleotide binding;GO:0042802//identical protein binding;GO:0061731//ribonucleoside-diphosphate reductase activity;GO:0097718//disordered domain specific binding"	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006281//DNA repair;GO:0008152//metabolic process;GO:0009185//ribonucleoside diphosphate metabolic process;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0009265//2'-deoxyribonucleotide biosynthetic process;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0051290//protein heterotetramerization;GO:0070318//positive regulation of G0 to G1 transition;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000167332	11.057	10.721	13.58	17.42	16.565	19.946	590	607	547	696	749	781	OR51E2	olfactory receptor family 51 subfamily E member 2 [Source:HGNC Symbol;Acc:HGNC:15195]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0043229//intracellular organelle	GO:0003707//steroid hormone receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0038023//signaling receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0016477//cell migration;GO:0030318//melanocyte differentiation;GO:0043401//steroid hormone mediated signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045777//positive regulation of blood pressure;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0071398//cellular response to fatty acid;GO:0097325//melanocyte proliferation;GO:1900135//positive regulation of renin secretion into blood stream	--
ENSG00000167333	7.507	7.465	9.474	9.726	9.216	9.664	504	470	385	424	495	390	TRIM68	tripartite motif containing 68 [Source:HGNC Symbol;Acc:HGNC:21161]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0035035//histone acetyltransferase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046596//regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:0060765//regulation of androgen receptor signaling pathway	--
ENSG00000167346	0	0	0	0	0	0	0	0	0	0	0	0	MMP26	matrix metallopeptidase 26 [Source:HGNC Symbol;Acc:HGNC:14249]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0050728//negative regulation of inflammatory response	--
ENSG00000167355	0	0	0	0	0	0	0	0	0	0	0	0	OR51B5	olfactory receptor family 51 subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:19599]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000167359	0	0	0	0	0	0	0	0	0	0	0	0	OR51I1	olfactory receptor family 51 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:15200]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000167360	0	0	0	0	0	0	0	0	0	0	0	0	OR51Q1	olfactory receptor family 51 subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:14851]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000167363	17.063	16.459	20.384	26.913	24.784	17.647	493	478	435	576	605	371	FN3K	fructosamine 3 kinase [Source:HGNC Symbol;Acc:HGNC:24822]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0102193//protein-ribulosamine 3-kinase activity;GO:0102194//protein-fructosamine 3-kinase activity	GO:0016310//phosphorylation;GO:0030389//fructosamine metabolic process;GO:0030393//fructoselysine metabolic process;GO:0030855//epithelial cell differentiation;GO:0036525//protein deglycation;GO:0043687//post-translational protein modification	--
ENSG00000167371	1.133	0.92	1.487	0.932	1.23	1.763	45.76	49.21	61.01	23.84	47.22	51.49	PRRT2	proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043679//axon terminus;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098793//presynapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0005515//protein binding;GO:0017075//syntaxin-1 binding	GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0035544//negative regulation of SNARE complex assembly;GO:0050884//neuromuscular process controlling posture;GO:0099502//calcium-dependent activation of synaptic vesicle fusion;GO:1905513//negative regulation of short-term synaptic potentiation	--
ENSG00000167377	2.516	2.497	2.707	1.818	1.848	2.098	134.61	131.91	98.66	63.42	85.15	84.5	ZNF23	zinc finger protein 23 [Source:HGNC Symbol;Acc:HGNC:13023]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167378	3.24	3.107	3.346	2.362	3.138	3.144	560	546	433	313	473	402	IRGQ	immunity related GTPase Q [Source:HGNC Symbol;Acc:HGNC:24868]	-	-	-	-	-	GO:0005515//protein binding;GO:0005525//GTP binding	-	--
ENSG00000167380	13.071	17.24	15.59	16.172	14.29	12.301	272	297	220	220	230	205	ZNF226	zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167384	3.139	2.478	3.119	2.123	2.511	2.732	224	172	154	116	147	123	ZNF180	zinc finger protein 180 [Source:HGNC Symbol;Acc:HGNC:12970]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167393	5.061	5.359	6.55	8.544	8.459	7.687	223	227	212	217	287	221	PPP2R3B	protein phosphatase 2 regulatory subunit B''beta [Source:HGNC Symbol;Acc:HGNC:13417]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Genetic Information Processing	Signal transduction;Infectious disease: viral;Circulatory system;Nervous system;Signal transduction;Signal transduction;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko03015//mRNA surveillance pathway	K11583;K11583;K11583;K11583;K11583;K11583;K11583	GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:0050790//regulation of catalytic activity;GO:0051726//regulation of cell cycle	--
ENSG00000167394	4.502	3.113	4.779	4.77	4.858	6.606	199	175	175	172	189	203	ZNF668	zinc finger protein 668 [Source:HGNC Symbol;Acc:HGNC:25821]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000167395	5.249	5.615	6.757	6.866	5.658	4.505	507	530.94	438	437	452	444	ZNF646	zinc finger protein 646 [Source:HGNC Symbol;Acc:HGNC:29004]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167397	86.975	85.802	91.346	86.926	79.11	82.373	1532.1	1518.15	1189.64	1133.93	1174	1055.63	VKORC1	vitamin K epoxide reductase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23663]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K05357;K05357	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016900//oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor;GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0047058//vitamin-K-epoxide reductase (warfarin-insensitive) activity;GO:0048038//quinone binding"	GO:0006805//xenobiotic metabolic process;GO:0007596//blood coagulation;GO:0010243//response to organonitrogen compound;GO:0014070//response to organic cyclic compound;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0030193//regulation of blood coagulation;GO:0042373//vitamin K metabolic process;GO:0046677//response to antibiotic;GO:0060348//bone development	--
ENSG00000167414	0.111	0	0	0	0	0	1	0	0	0	0	0	GNG8	G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544;K04544	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035176//social behavior;GO:0043584//nose development;GO:0071444//cellular response to pheromone	--
ENSG00000167419	0	0	0	0.055	0	0.028	0	0	0	2	0	1	LPO	lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678]	Human Diseases;Organismal Systems	Cancer: overview;Digestive system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04970//Salivary secretion	K12550;K12550	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0036393//thiocyanate peroxidase activity;GO:0046872//metal ion binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006979//response to oxidative stress;GO:0018969//thiocyanate metabolic process;GO:0042742//defense response to bacterium;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000167434	0.043	0.137	0.058	0.29	0	0	1	2	1	5	0	0	CA4	carbonic anhydrase 4 [Source:HGNC Symbol;Acc:HGNC:1375]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Excretory system;Energy metabolism	ko01100//Metabolic pathways;ko04964//Proximal tubule bicarbonate reclamation;ko00910//Nitrogen metabolism	K18246;K18246;K18246	GO:0005791//rough endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031526//brush border membrane;GO:0046658//anchored component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process;GO:0015701//bicarbonate transport	--
ENSG00000167447	7.985	7.674	8.84	8.368	8.442	9.172	538	518	438	415	467	438	SMG8	SMG8 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:25551]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045859//regulation of protein kinase activity"	--
ENSG00000167460	109.019	103.942	93.037	101.865	101.045	103.582	5652	5410	3556	3911	4444	3867	TPM4	tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K10375;K10375;K10375;K10375	GO:0001725//stress fiber;GO:0002102//podosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005862//muscle thin filament tropomyosin;GO:0005884//actin filament;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding	GO:0001649//osteoblast differentiation;GO:0006936//muscle contraction;GO:0007015//actin filament organization	--
ENSG00000167461	20.304	20.56	23.111	20.983	19.274	19.592	1046	1063	808	796	867	759	RAB8A	"RAB8A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:7007]"	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Cellular community - eukaryotes;Transport and catabolism;Signal transduction;Digestive system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04144//Endocytosis;ko04530//Tight junction;ko04140//Autophagy - animal;ko04152//AMPK signaling pathway;ko04972//Pancreatic secretion	K07901;K07901;K07901;K07901;K07901;K07901;K07901	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0030425//dendrite;GO:0030496//midbody;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0097546//ciliary base;GO:0097730//non-motile cilium;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0031489//myosin V binding	"GO:0006904//vesicle docking involved in exocytosis;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0007409//axonogenesis;GO:0009306//protein secretion;GO:0010506//regulation of autophagy;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0030030//cell projection organization;GO:0032869//cellular response to insulin stimulus;GO:0032880//regulation of protein localization;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048210//Golgi vesicle fusion to target membrane;GO:0051223//regulation of protein transport;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:0072659//protein localization to plasma membrane;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0098969//neurotransmitter receptor transport to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse"	--
ENSG00000167468	507.113	524.792	550.136	628.465	564.477	555.702	8394	8714	6758	7697	7876	6675	GPX4	glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556]	Metabolism;Metabolism;Cellular Processes	Global and overview maps;Metabolism of other amino acids;Cell growth and death	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko04216//Ferroptosis	K05361;K05361;K05361	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0047066//phospholipid-hydroperoxide glutathione peroxidase activity	GO:0006325//chromatin organization;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006749//glutathione metabolic process;GO:0006979//response to oxidative stress;GO:0007283//spermatogenesis;GO:0007568//aging;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0032355//response to estradiol;GO:0042759//long-chain fatty acid biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0051258//protein polymerization;GO:0098869//cellular oxidant detoxification;GO:0110076//negative regulation of ferroptosis	--
ENSG00000167470	6.907	7.03	6.684	6.509	7.178	5.207	483	504	367	354	441	275	MIDN	midnolin [Source:HGNC Symbol;Acc:HGNC:16298]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0019900//kinase binding	GO:0008150//biological_process;GO:0033132//negative regulation of glucokinase activity;GO:0046676//negative regulation of insulin secretion	--
ENSG00000167476	4.787	6.238	4.589	6.177	4.914	5.24	113	148	80	108	98	90	JSRP1	junctional sarcoplasmic reticulum protein 1 [Source:HGNC Symbol;Acc:HGNC:24963]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane	GO:0005515//protein binding	GO:0003009//skeletal muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity	--
ENSG00000167483	0.1	0.084	0.064	0.064	0.075	0.155	8	9	5	5	5	12	NIBAN3	niban apoptosis regulator 3 [Source:HGNC Symbol;Acc:HGNC:24130]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000167487	3.469	1.907	2.269	1.975	2.243	2.711	167	173	137	132	171	137	KLHL26	kelch like family member 26 [Source:HGNC Symbol;Acc:HGNC:25623]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000167491	19.37	22.6	22.829	13.965	16.479	24.79	1443	1438	1102	964	1107	1157	GATAD2A	GATA zinc finger domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29989]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016581//NuRD complex;GO:0016607//nuclear speck;GO:0043229//intracellular organelle	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000736//regulation of stem cell differentiation"	zf-GATA
ENSG00000167508	15.865	18.509	20.3	20.622	19.056	18.967	505	511	448	512	528	453	MVD	mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529]	Metabolism;Metabolism	Global and overview maps;Metabolism of terpenoids and polyketides	ko01100//Metabolic pathways;ko00900//Terpenoid backbone biosynthesis	K01597;K01597	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004163//diphosphomevalonate decarboxylase activity;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0030544//Hsp70 protein binding;GO:0042803//protein homodimerization activity	"GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008299//isoprenoid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway"	--
ENSG00000167513	9.031	9.467	6.224	3.563	3.449	3.955	499	501	254	126	161	159	CDT1	chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body"	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0070182//DNA polymerase binding	GO:0000076//DNA replication checkpoint signaling;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0033044//regulation of chromosome organization;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0035563//positive regulation of chromatin binding;GO:0045740//positive regulation of DNA replication;GO:0045786//negative regulation of cell cycle;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051383//kinetochore organization;GO:0071163//DNA replication preinitiation complex assembly;GO:0072708//response to sorbitol;GO:1902426//deactivation of mitotic spindle assembly checkpoint;GO:1902595//regulation of DNA replication origin binding;GO:1905341//negative regulation of protein localization to kinetochore;GO:1905342//positive regulation of protein localization to kinetochore;GO:2000104//negative regulation of DNA-dependent DNA replication;GO:2000105//positive regulation of DNA-dependent DNA replication	--
ENSG00000167515	25.007	26.447	21.704	29.22	28.665	26.471	704	789	559	670	654	626	TRAPPC2L	trafficking protein particle complex subunit 2L [Source:HGNC Symbol;Acc:HGNC:30887]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000167522	29.525	29.574	28.166	28.356	27.363	28.447	2696	2530	1766	1631	1954	1744	ANKRD11	ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0009653//anatomical structure morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048705//skeletal system morphogenesis;GO:0060325//face morphogenesis	--
ENSG00000167523	4.5	4.019	5.159	2.624	3.243	3.387	136	137	109	54	92	83	SPATA33	spermatogenesis associated 33 [Source:HGNC Symbol;Acc:HGNC:26463]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000167524	0.621	0.516	0.792	0.697	0.503	0.365	29.27	31.6	36.8	28.05	21.57	13.31	RSKR	ribosomal protein S6 kinase related [Source:HGNC Symbol;Acc:HGNC:26314]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000167525	0.347	0.844	1.022	1.018	1.104	0.596	8	16	14	17	20	10	PROCA1	protein interacting with cyclin A1 [Source:HGNC Symbol;Acc:HGNC:28600]	-	-	-	-	-	GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0030332//cyclin binding	GO:0006644//phospholipid metabolic process;GO:0050482//arachidonic acid secretion	--
ENSG00000167526	828.512	870.19	839.274	989.298	860.495	788.26	16572	17510	12323	14483	14743	11618	RPL13	ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:10303]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02873;K02873	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0001824//blastocyst development;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0060348//bone development	--
ENSG00000167528	8.008	7.9	8.269	7.472	8.132	8.505	736	821	580	564	648	638	ZNF641	zinc finger protein 641 [Source:HGNC Symbol;Acc:HGNC:31834]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167531	0	0	0	0	0	0	0	0	0	0	0	0	LALBA	lactalbumin alpha [Source:HGNC Symbol;Acc:HGNC:6480]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00052//Galactose metabolism	K00704;K00704	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0004461//lactose synthase activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0005989//lactose biosynthetic process;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0042742//defense response to bacterium	--
ENSG00000167535	7.966	8.4	7.604	5.95	7.457	7.942	403	430	281	256	331	297	CACNB3	calcium voltage-gated channel auxiliary subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1403]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04864;K04864;K04864;K04864;K04864;K04864;K04864	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0045202//synapse;GO:1990454//L-type voltage-gated calcium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005246//calcium channel regulator activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0034765//regulation of ion transmembrane transport;GO:0050852//T cell receptor signaling pathway;GO:0060402//calcium ion transport into cytosol;GO:0061577//calcium ion transmembrane transport via high voltage-gated calcium channel;GO:0070588//calcium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:0098903//regulation of membrane repolarization during action potential;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1901843//positive regulation of high voltage-gated calcium channel activity	--
ENSG00000167536	10.476	10.401	11.792	14.069	12.009	12.554	421	420	351	420	408	368	DHRS13	dehydrogenase/reductase 13 [Source:HGNC Symbol;Acc:HGNC:28326]	-	-	-	-	GO:0005576//extracellular region;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0016491//oxidoreductase activity;GO:0052650//NADP-retinol dehydrogenase activity	GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process	--
ENSG00000167543	11.199	14.44	16.573	20.435	15.151	15.509	329	423	365	450	379	327	TP53I13	tumor protein p53 inducible protein 13 [Source:HGNC Symbol;Acc:HGNC:25102]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0009410//response to xenobiotic stimulus;GO:0009411//response to UV;GO:0014070//response to organic cyclic compound;GO:0045786//negative regulation of cell cycle	--
ENSG00000167548	7.438	8.411	9.735	8.277	8.715	9.859	1878	1938.01	1619.31	1508.24	2077.13	1715	KMT2D	lysine methyltransferase 2D [Source:HGNC Symbol;Acc:HGNC:7133]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Endocrine and metabolic disease;Amino acid metabolism	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00310//Lysine degradation	K09187;K09187;K09187	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0044666//MLL3/4 complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042393//histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046872//metal ion binding	"GO:0001555//oocyte growth;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0031507//heterochromatin assembly;GO:0032259//methylation;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0043627//response to estrogen;GO:0044648//histone H3-K4 dimethylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048477//oogenesis;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0097692//histone H3-K4 monomethylation;GO:1904837//beta-catenin-TCF complex assembly"	--
ENSG00000167549	0.126	0.181	0.289	0.315	0.433	0.244	7	7	7	11	12	7	CORO6	coronin 6 [Source:HGNC Symbol;Acc:HGNC:21356]	-	-	-	-	-	GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0016477//cell migration	--
ENSG00000167550	0.164	0.123	0.246	0	0	0	4	3	4	0	0	0	RHEBL1	RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0031929//TOR signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000167552	458.794	494.357	455.387	432.02	401.295	402.941	15915.26	17242.74	11680.2	11109.86	11771.32	10175.12	TUBA1A	tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0031594//neuromuscular junction;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0050807//regulation of synapse organization;GO:0051301//cell division	--
ENSG00000167553	242.618	247.643	263.784	309.535	271.922	312.279	6156.11	6522.39	4979.58	5862.39	6015.24	5766.38	TUBA1C	tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0015630//microtubule cytoskeleton;GO:0031982//vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division	--
ENSG00000167554	1.787	2.583	2.416	1.672	2.242	2.394	84	122	56	55	78	65	ZNF610	zinc finger protein 610 [Source:HGNC Symbol;Acc:HGNC:26687]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167555	0.386	0.096	0.049	0.033	0.029	0.254	7	8	3	2	2	3	ZNF528	zinc finger protein 528 [Source:HGNC Symbol;Acc:HGNC:29384]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167562	2.33	1.702	1.554	0.939	1.732	1.013	153.43	118.69	72	57	98	48	ZNF701	zinc finger protein 701 [Source:HGNC Symbol;Acc:HGNC:25597]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167565	10.207	9.686	9.788	11.354	11.811	12.048	281	273	200	235	283	239	SERTAD3	SERTA domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17931]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000167566	12.356	12.731	14.517	16.607	15.16	15.504	1235	1279	1063	1223	1269	1128	NCKAP5L	NCK associated protein 5 like [Source:HGNC Symbol;Acc:HGNC:29321]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0035371//microtubule plus-end	GO:0005515//protein binding	GO:0001578//microtubule bundle formation;GO:0007019//microtubule depolymerization	--
ENSG00000167578	4.854	6.145	4.476	5.68	7.862	6.538	107.61	144.92	75	99.41	142	110.87	RAB4B	"RAB4B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9782]"	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0032593//insulin-responsive compartment;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0032482//Rab protein signal transduction;GO:0046323//glucose import	--
ENSG00000167580	0	0	0	0	0	0	0	0	0	0	0	0	AQP2	aquaporin 2 [Source:HGNC Symbol;Acc:HGNC:634]	Organismal Systems	Excretory system	ko04962//Vasopressin-regulated water reabsorption	K09865	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030658//transport vesicle membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0098576//lumenal side of membrane	GO:0005372//water transmembrane transporter activity;GO:0005515//protein binding;GO:0015168//glycerol transmembrane transporter activity;GO:0015250//water channel activity;GO:0015267//channel activity	GO:0003091//renal water homeostasis;GO:0003097//renal water transport;GO:0006833//water transport;GO:0015793//glycerol transport;GO:0042631//cellular response to water deprivation;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0071280//cellular response to copper ion;GO:0071288//cellular response to mercury ion;GO:0072205//metanephric collecting duct development	--
ENSG00000167588	1.987	2.276	1.47	2.66	3.538	2.215	119	137	65	118	179	89	GPD1	glycerol-3-phosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:4455]	Metabolism	Lipid metabolism	ko00564//Glycerophospholipid metabolism	K00006	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0070062//extracellular exosome	"GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity;GO:0004368//glycerol-3-phosphate dehydrogenase (quinone) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042803//protein homodimerization activity;GO:0051287//NAD binding"	GO:0005975//carbohydrate metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006094//gluconeogenesis;GO:0006116//NADH oxidation;GO:0006127//glycerophosphate shuttle;GO:0006734//NADH metabolic process;GO:0045821//positive regulation of glycolytic process;GO:0046168//glycerol-3-phosphate catabolic process;GO:0046486//glycerolipid metabolic process;GO:0071320//cellular response to cAMP;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000167595	3.051	3.598	3.51	3.204	3.392	3.165	169	186	125	105	143	123	PROSER3	proline and serine rich 3 [Source:HGNC Symbol;Acc:HGNC:25204]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000167600	7.047	6.685	7.267	7.924	8.659	6.849	333	319	265	318	379	270	CYP2S1	cytochrome P450 family 2 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:15654]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00830//Retinol metabolism	K07420;K07420;K07420	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004796//thromboxane-A synthase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0036134//12-hydroxyheptadecatrienoic acid synthase activity;GO:0046872//metal ion binding;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042573//retinoic acid metabolic process	--
ENSG00000167601	17.063	17.419	15.214	15.223	17.203	14.001	1394	1353	938	928	1182	816	AXL	AXL receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:905]	Human Diseases	Drug resistance: antineoplastic	ko01521//EGFR tyrosine kinase inhibitor resistance	K05115	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0044228//host cell surface;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0001786//phosphatidylserine binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0032036//myosin heavy chain binding;GO:0043548//phosphatidylinositol 3-kinase binding	GO:0001764//neuron migration;GO:0001779//natural killer cell differentiation;GO:0001818//negative regulation of cytokine production;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0001974//blood vessel remodeling;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021885//forebrain cell migration;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0031100//animal organ regeneration;GO:0031668//cellular response to extracellular stimulus;GO:0032689//negative regulation of interferon-gamma production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032825//positive regulation of natural killer cell differentiation;GO:0032940//secretion by cell;GO:0033674//positive regulation of kinase activity;GO:0034101//erythrocyte homeostasis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035457//cellular response to interferon-alpha;GO:0042698//ovulation cycle;GO:0043066//negative regulation of apoptotic process;GO:0043277//apoptotic cell clearance;GO:0043491//protein kinase B signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0045087//innate immune response;GO:0046718//viral entry into host cell;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048469//cell maturation;GO:0048549//positive regulation of pinocytosis;GO:0051250//negative regulation of lymphocyte activation;GO:0051897//positive regulation of protein kinase B signaling;GO:0060068//vagina development;GO:0070301//cellular response to hydrogen peroxide;GO:0071222//cellular response to lipopolysaccharide;GO:0097028//dendritic cell differentiation;GO:0097350//neutrophil clearance;GO:1903902//positive regulation of viral life cycle;GO:2000669//negative regulation of dendritic cell apoptotic process	--
ENSG00000167604	0.626	0.501	0.74	0.616	0.923	0.828	20	17	18	15	26	20	NFKBID	NFKB inhibitor delta [Source:HGNC Symbol;Acc:HGNC:15671]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0010468//regulation of gene expression;GO:0050852//T cell receptor signaling pathway;GO:2000321//positive regulation of T-helper 17 cell differentiation	--
ENSG00000167608	0.239	0.474	0.055	0.544	0.145	0.578	3	15	2	11	6	7	TMC4	transmembrane channel like 4 [Source:HGNC Symbol;Acc:HGNC:22998]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000167612	0	0.026	0	0.035	0	0	0	1	0	1	0	0	ANKRD33	ankyrin repeat domain 33 [Source:HGNC Symbol;Acc:HGNC:13788]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0035914//skeletal muscle cell differentiation;GO:2000678//negative regulation of transcription regulatory region DNA binding	--
ENSG00000167613	0	0	0	0	0.078	0	0	0	0	0	2	0	LAIR1	leukocyte associated immunoglobulin like receptor 1 [Source:HGNC Symbol;Acc:HGNC:6477]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000167614	11.121	11.621	13.51	16.625	16.436	15.623	467	490	419	519	582	472	TTYH1	tweety family member 1 [Source:HGNC Symbol;Acc:HGNC:13476]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0031527//filopodium membrane;GO:0032433//filopodium tip;GO:0034707//chloride channel complex;GO:0045202//synapse	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0005381//iron ion transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0072320//volume-sensitive chloride channel activity	GO:0000278//mitotic cell cycle;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006826//iron ion transport;GO:0007155//cell adhesion;GO:0031589//cell-substrate adhesion;GO:0034220//ion transmembrane transport;GO:0034755//iron ion transmembrane transport;GO:0046847//filopodium assembly;GO:0098609//cell-cell adhesion	--
ENSG00000167615	14.264	18.366	16.675	17.157	19.172	17.019	952	954	795.92	835.91	1074.91	782	LENG8	leukocyte receptor cluster member 8 [Source:HGNC Symbol;Acc:HGNC:15500]	-	-	-	-	GO:0005634//nucleus;GO:0032991//protein-containing complex	GO:0005515//protein binding	-	--
ENSG00000167617	1.399	0.91	1.093	1.816	2.293	0.813	26	17	15	25	36	11	CDC42EP5	CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0031267//small GTPase binding	GO:0007254//JNK cascade;GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly	--
ENSG00000167618	0	0	0	0	0	0	0	0	0	0	0	0	LAIR2	leukocyte associated immunoglobulin like receptor 2 [Source:HGNC Symbol;Acc:HGNC:6478]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	GO:0005515//protein binding	-	--
ENSG00000167619	0.051	0.048	0.33	0.268	0.163	0.301	2	2	10	10	6	9	TMEM145	transmembrane protein 145 [Source:HGNC Symbol;Acc:HGNC:26912]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007186//G protein-coupled receptor signaling pathway;GO:0019236//response to pheromone	--
ENSG00000167625	2.942	2.833	2.975	3.007	2.923	3.045	243	235.2	167.02	184	204	183	ZNF526	zinc finger protein 526 [Source:HGNC Symbol;Acc:HGNC:29415]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000167632	13.863	13.853	15.768	16.62	17.152	14.84	1321	1355	1152	1169	1364	1082	TRAPPC9	trafficking protein particle complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:30832]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0110165//cellular anatomical entity;GO:1990071//TRAPPII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0099022//vesicle tethering	--
ENSG00000167633	0	0	0	0	0	0	0	0	0	0	0	0	KIR3DL1	"killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 [Source:HGNC Symbol;Acc:HGNC:6338]"	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K07980;K07980;K07980	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030109//HLA-B specific inhibitory MHC class I receptor activity	GO:0006955//immune response;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000167634	0	0	0	0	0	0	0	0	0	0	0	0	NLRP7	NLR family pyrin domain containing 7 [Source:HGNC Symbol;Acc:HGNC:22947]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20864	GO:0005575//cellular_component	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0019966//interleukin-1 binding;GO:0042802//identical protein binding;GO:0089720//caspase binding	GO:0010951//negative regulation of endopeptidase activity;GO:0010955//negative regulation of protein processing;GO:0032691//negative regulation of interleukin-1 beta production;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1905246//negative regulation of aspartic-type peptidase activity	--
ENSG00000167635	16.437	13.818	13.554	9.391	11.343	10.742	1152	976	700	487	666	547	ZNF146	zinc finger protein 146 [Source:HGNC Symbol;Acc:HGNC:12931]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167637	1.659	1.596	2.114	3.359	1.649	1.655	118	89	55.03	63	82	71	ZNF283	zinc finger protein 283 [Source:HGNC Symbol;Acc:HGNC:13077]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167641	2.611	4.064	1.715	0.232	1.041	0.572	34	52	18	2	11	5	PPP1R14A	protein phosphatase 1 regulatory inhibitor subunit 14A [Source:HGNC Symbol;Acc:HGNC:14871]	Organismal Systems	Circulatory system	ko04270//Vascular smooth muscle contraction	K12328	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity	GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity	--
ENSG00000167642	82.65	88.03	71.415	78.92	80.247	83.371	2829.98	3033	1815	2012.99	2357.97	1950	SPINT2	"serine peptidase inhibitor, Kunitz type 2 [Source:HGNC Symbol;Acc:HGNC:11247]"	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0001843//neural tube closure;GO:0007163//establishment or maintenance of cell polarity;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0022408//negative regulation of cell-cell adhesion;GO:0060672//epithelial cell morphogenesis involved in placental branching;GO:0071711//basement membrane organization;GO:0071773//cellular response to BMP stimulus;GO:2000146//negative regulation of cell motility;GO:2000178//negative regulation of neural precursor cell proliferation	--
ENSG00000167644	7.179	8.306	6.103	6.995	7.031	5.004	60	70.95	38	44	49.97	31	C19orf33	chromosome 19 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:16668]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	-	GO:0008150//biological_process	--
ENSG00000167645	25.394	25.473	27.576	35.324	26.917	31.155	534	532.05	455.06	535	512	467	YIF1B	"Yip1 interacting factor homolog B, membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:30511]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding	GO:0006612//protein targeting to membrane;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport	--
ENSG00000167646	2.743	2.486	4.175	2.561	2.551	3.73	99	101	122	61	84	97	DNAAF3	dynein axonemal assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:30492]	-	-	-	-	GO:0005737//cytoplasm;GO:0120293//dynein axonemal particle	-	GO:0030030//cell projection organization;GO:0044458//motile cilium assembly;GO:0070286//axonemal dynein complex assembly	--
ENSG00000167653	0	0	0	0.199	0	0.067	0	0	0	3	0	1	PSCA	prostate stem cell antigen [Source:HGNC Symbol;Acc:HGNC:9500]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome	GO:0033130//acetylcholine receptor binding	GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0099601//regulation of neurotransmitter receptor activity	--
ENSG00000167654	0.019	0.128	0	0.033	0.059	0.037	2	11	0	1	3	2	ATCAY	ATCAY kinesin light chain interacting caytaxin [Source:HGNC Symbol;Acc:HGNC:779]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031966//mitochondrial membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0031175//neuron projection development;GO:0032880//regulation of protein localization;GO:0048311//mitochondrion distribution;GO:2000212//negative regulation of glutamate metabolic process	--
ENSG00000167656	0	0	0	0	0	0	0	0	0	0	0	0	LY6D	lymphocyte antigen 6 family member D [Source:HGNC Symbol;Acc:HGNC:13348]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0030098//lymphocyte differentiation;GO:0035634//response to stilbenoid	--
ENSG00000167657	29.863	27.953	30.892	31.783	31.624	28.982	842	828	695	662	750	629	DAPK3	death associated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:2676]	Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Transport and catabolism;Cancer: specific types	ko05200//Pathways in cancer;ko04140//Autophagy - animal;ko05219//Bladder cancer	K08803;K08803;K08803	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008140//cAMP response element binding protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043522//leucine zipper domain binding;GO:0106310//protein serine kinase activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006940//regulation of smooth muscle contraction;GO:0007088//regulation of mitotic nuclear division;GO:0007346//regulation of mitotic cell cycle;GO:0008360//regulation of cell shape;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0017148//negative regulation of translation;GO:0030335//positive regulation of cell migration;GO:0035556//intracellular signal transduction;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043519//regulation of myosin II filament organization;GO:0046777//protein autophosphorylation;GO:0051893//regulation of focal adhesion assembly;GO:0071346//cellular response to interferon-gamma;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097190//apoptotic signaling pathway;GO:2000145//regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization"	--
ENSG00000167658	1372.513	1401.535	1384.815	1658.688	1549.621	1335.554	89904	92277	66995	80480	85757	63653	EEF2	eukaryotic translation elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:3214]	Organismal Systems;Environmental Information Processing	Endocrine system;Signal transduction	ko04921//Oxytocin signaling pathway;ko04152//AMPK signaling pathway	K03234;K03234	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016235//aggresome;GO:0034774//secretory granule lumen;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0043022//ribosome binding;GO:0045296//cadherin binding	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006412//translation;GO:0006414//translational elongation;GO:0045727//positive regulation of translation	--
ENSG00000167664	0	0	0	0	0	0	0	0	0	0	0	0	TMIGD2	transmembrane and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28324]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015026//coreceptor activity	GO:0001819//positive regulation of cytokine production;GO:0006955//immune response;GO:0031295//T cell costimulation;GO:0042104//positive regulation of activated T cell proliferation;GO:0045766//positive regulation of angiogenesis	--
ENSG00000167670	4.768	4.289	3.355	3.395	2.79	2.224	283	301	173	157	153	113	CHAF1A	chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0032991//protein-containing complex;GO:0033186//CAF-1 complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding;GO:0070087//chromo shadow domain binding	GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031497//chromatin assembly	--
ENSG00000167671	80.982	77.086	94.018	105.846	98.495	98.642	2570	2644	2007	2506	2542	2243	UBXN6	UBX domain protein 6 [Source:HGNC Symbol;Acc:HGNC:14928]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14011	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0016236//macroautophagy;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0036503//ERAD pathway	--
ENSG00000167674	30.264	30.046	31.371	30.336	32.479	28.348	1376	1387	1068	1022	1229	942	HDGFL2	HDGF like 2 [Source:HGNC Symbol;Acc:HGNC:14680]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0061628//H3K27me3 modified histone binding;GO:0062072//H3K9me3 modified histone binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0030307//positive regulation of cell growth;GO:0042692//muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:1905168//positive regulation of double-strand break repair via homologous recombination	--
ENSG00000167676	8.97	11.146	10.481	7.417	9.119	6.547	1209	1510	1043	740	1038	642	PLIN4	perilipin 4 [Source:HGNC Symbol;Acc:HGNC:29393]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K20254	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	-	-	--
ENSG00000167680	1.46	1.5	1.913	1.393	1.651	1.421	107	119	91	80	102	68	SEMA6B	semaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06842	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0021766//hippocampus development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000167685	12.843	12.619	13.97	12.897	15.704	15.667	470	396	361	339	482	430	ZNF444	zinc finger protein 444 [Source:HGNC Symbol;Acc:HGNC:16052]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000167693	59.104	60.494	67.647	78.201	77.072	75.835	3623	3706.81	3060	3473	3988	3404	NXN	nucleoredoxin [Source:HGNC Symbol;Acc:HGNC:18008]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004791//thioredoxin-disulfide reductase activity;GO:0016491//oxidoreductase activity;GO:0047134//protein-disulfide reductase (NAD(P)) activity	GO:0001701//in utero embryonic development;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0072359//circulatory system development;GO:0098869//cellular oxidant detoxification	--
ENSG00000167695	20.67	20.629	19.853	20.832	22.769	18.529	771	790	561	559	633	490	TLCD3A	TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008150//biological_process;GO:0055088//lipid homeostasis	--
ENSG00000167699	24.164	23.157	25.153	25.736	24.653	24.012	877	828	656	683	724	629	GLOD4	glyoxalase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:14111]	-	-	-	-	GO:0005739//mitochondrion;GO:0070062//extracellular exosome	GO:0045296//cadherin binding	-	--
ENSG00000167700	15.812	17.245	19.936	23.694	21.767	21.688	509	558	474	565	592	508	MFSD3	major facilitator superfamily domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25157]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015295//solute:proton symporter activity;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000167701	0.291	0.789	0.609	0.749	0.876	0.544	11	30	17	21	28	15	GPT	glutamic--pyruvic transaminase [Source:HGNC Symbol;Acc:HGNC:4552]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Global and overview maps	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism"	K00814;K00814;K00814;K00814;K00814;K00814	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004021//L-alanine:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding	GO:0009058//biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0042594//response to starvation;GO:0042853//L-alanine catabolic process;GO:0045722//positive regulation of gluconeogenesis	--
ENSG00000167702	2.124	2.76	3.017	2.928	2.96	3.151	144	183	145	137	169.41	155	KIFC2	kinesin family member C2 [Source:HGNC Symbol;Acc:HGNC:29530]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement;GO:0090307//mitotic spindle assembly	--
ENSG00000167703	4.7	6.365	4.586	3.628	3.971	2.841	290.02	310	167	176.06	230	142	SLC43A2	solute carrier family 43 member 2 [Source:HGNC Symbol;Acc:HGNC:23087]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0051956//negative regulation of amino acid transport;GO:0055085//transmembrane transport;GO:0060358//negative regulation of leucine import;GO:1902475//L-alpha-amino acid transmembrane transport	--
ENSG00000167705	7.064	6.034	7.939	7.245	6.112	6.074	218	190	184	167	159	143	RILP	Rab interacting lysosomal protein [Source:HGNC Symbol;Acc:HGNC:30266]	Human Diseases;Cellular Processes	Infectious disease: bacterial;Transport and catabolism	ko05132//Salmonella infection;ko04145//Phagosome	K13883;K13883	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046983//protein dimerization activity;GO:0051959//dynein light intermediate chain binding	GO:0008333//endosome to lysosome transport;GO:0010796//regulation of multivesicular body size;GO:0015031//protein transport;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0042177//negative regulation of protein catabolic process;GO:0045022//early endosome to late endosome transport;GO:0045732//positive regulation of protein catabolic process;GO:0060271//cilium assembly;GO:0070676//intralumenal vesicle formation	--
ENSG00000167711	33.128	30.995	38.637	36.089	35.134	43.418	1532	1457	1331	1236	1397	1454	SERPINF2	serpin family F member 2 [Source:HGNC Symbol;Acc:HGNC:9075]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03983	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0042803//protein homodimerization activity	GO:0002034//maintenance of blood vessel diameter homeostasis by renin-angiotensin;GO:0006953//acute-phase response;GO:0010466//negative regulation of peptidase activity;GO:0010757//negative regulation of plasminogen activation;GO:0010951//negative regulation of endopeptidase activity;GO:0030199//collagen fibril organization;GO:0032967//positive regulation of collagen biosynthetic process;GO:0042730//fibrinolysis;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048514//blood vessel morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051496//positive regulation of stress fiber assembly;GO:0051918//negative regulation of fibrinolysis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071636//positive regulation of transforming growth factor beta production;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin	--
ENSG00000167716	18.238	15.299	19.506	19.754	17.294	22.766	2263	2227	1977	1952	2116	2238	WDR81	WD repeat domain 81 [Source:HGNC Symbol;Acc:HGNC:26600]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031313//extrinsic component of endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane	GO:0005515//protein binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007005//mitochondrion organization;GO:0035973//aggrephagy;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045022//early endosome to late endosome transport;GO:0050821//protein stabilization	--
ENSG00000167720	9.732	9.669	8.753	7.413	7.611	8.241	474.02	493.62	326.12	275.78	317.33	288.87	SRR	serine racemase [Source:HGNC Symbol;Acc:HGNC:14398]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko00260//Glycine, serine and threonine metabolism;ko00470//D-Amino acid metabolism"	K12235;K12235;K12235	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0045177//apical part of cell	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0003941//L-serine ammonia-lyase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008721//D-serine ammonia-lyase activity;GO:0016594//glycine binding;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0018114//threonine racemase activity;GO:0030165//PDZ domain binding;GO:0030170//pyridoxal phosphate binding;GO:0030378//serine racemase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006520//cellular amino acid metabolic process;GO:0006563//L-serine metabolic process;GO:0007420//brain development;GO:0007568//aging;GO:0008152//metabolic process;GO:0009069//serine family amino acid metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0032496//response to lipopolysaccharide;GO:0042866//pyruvate biosynthetic process;GO:0043278//response to morphine;GO:0070178//D-serine metabolic process;GO:0070179//D-serine biosynthetic process	--
ENSG00000167721	9.604	10.943	10.086	8.442	8.959	7.92	826.98	909.38	644.88	499.22	640.67	482.13	TSR1	TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor"	GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0034511//U3 snoRNA binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000479//endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042254//ribosome biogenesis"	--
ENSG00000167723	0.599	0.598	0.584	0.83	0.661	1.009	65	63	46	53	58	80.19	TRPV3	transient receptor potential cation channel subfamily V member 3 [Source:HGNC Symbol;Acc:HGNC:18084]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04972	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0009266//response to temperature stimulus;GO:0009408//response to heat;GO:0034220//ion transmembrane transport;GO:0042636//negative regulation of hair cycle;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0090280//positive regulation of calcium ion import;GO:0098703//calcium ion import across plasma membrane	--
ENSG00000167733	15.12	13.642	15.632	13.343	15.961	16.562	397	352	311	263	321	326.19	HSD11B1L	hydroxysteroid 11-beta dehydrogenase 1 like [Source:HGNC Symbol;Acc:HGNC:30419]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00140//Steroid hormone biosynthesis	K15680;K15680;K15680;K15680	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0016491//oxidoreductase activity	-	--
ENSG00000167740	14.994	15.336	16.337	15.609	15.483	15.271	551	596.13	429	431	514	450	CYB5D2	cytochrome b5 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28471]	-	-	-	-	GO:0005576//extracellular region;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005515//protein binding;GO:0020037//heme binding	GO:0007399//nervous system development;GO:0045666//positive regulation of neuron differentiation	--
ENSG00000167741	0	0	0	0	0	0	0	0	0	0	0	0	GGT6	gamma-glutamyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:26891]	Metabolism;Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K00681;K00681;K00681	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0036374//glutathione hydrolase activity;GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0103068//leukotriene C4 gamma-glutamyl transferase activity	GO:0006508//proteolysis;GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0008150//biological_process;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000167748	0	0	0	0	0	0	0	0	0	0	0	0	KLK1	kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357]	Organismal Systems;Organismal Systems	Excretory system;Endocrine system	ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04614//Renin-angiotensin system	K01325;K01325	GO:0005634//nucleus;GO:0030141//secretory granule;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0003073//regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0031638//zymogen activation	--
ENSG00000167749	0.034	0.158	0.107	0.046	0.04	0.374	1	4	2	1	1	8	KLK4	kallikrein related peptidase 4 [Source:HGNC Symbol;Acc:HGNC:6365]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030163//protein catabolic process;GO:0031214//biomineral tissue development;GO:0097186//amelogenesis	--
ENSG00000167751	0	0	0	0	0	0	0	0	0	0	0	0	KLK2	kallikrein related peptidase 2 [Source:HGNC Symbol;Acc:HGNC:6363]	Organismal Systems;Organismal Systems	Excretory system;Endocrine system	ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04614//Renin-angiotensin system	K01325;K01325	GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0003073//regulation of systemic arterial blood pressure;GO:0006508//proteolysis;GO:0031638//zymogen activation	--
ENSG00000167754	0.071	0.166	0.191	0.286	0.167	0.049	2	3	4	6	4	1	KLK5	kallikrein related peptidase 5 [Source:HGNC Symbol;Acc:HGNC:6366]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0097209//epidermal lamellar body	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0002803//positive regulation of antibacterial peptide production;GO:0006508//proteolysis;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0070268//cornification;GO:0097186//amelogenesis	--
ENSG00000167755	0.036	0.168	0	0.048	0.084	0	1	5	0	1	2	0	KLK6	kallikrein related peptidase 6 [Source:HGNC Symbol;Acc:HGNC:6367]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0030141//secretory granule;GO:0043231//intracellular membrane-bounded organelle	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007417//central nervous system development;GO:0009611//response to wounding;GO:0010975//regulation of neuron projection development;GO:0016540//protein autoprocessing;GO:0030574//collagen catabolic process;GO:0042246//tissue regeneration;GO:0042445//hormone metabolic process;GO:0042552//myelination;GO:0042982//amyloid precursor protein metabolic process;GO:0045595//regulation of cell differentiation;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway	--
ENSG00000167757	70.356	80.921	83.229	84.461	87.363	76.146	1679	1957	1487	1479	1738	1326	KLK11	kallikrein related peptidase 11 [Source:HGNC Symbol;Acc:HGNC:6359]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0030141//secretory granule;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000167759	0.93	1.013	1.005	0.543	0.728	0.696	28	20	17	12	15	13	KLK13	kallikrein related peptidase 13 [Source:HGNC Symbol;Acc:HGNC:6361]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030141//secretory granule	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016485//protein processing	--
ENSG00000167766	4.519	3.609	3.293	3.366	3.983	2.94	246.19	199	140	123	170	121	ZNF83	zinc finger protein 83 [Source:HGNC Symbol;Acc:HGNC:13158]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167767	3.586	3.621	1.916	6.182	8.013	7.082	289	293	114	369	545	415	KRT80	keratin 80 [Source:HGNC Symbol;Acc:HGNC:27056]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000167768	0	0	0	0	0	0	0	0	0	0	0	0	KRT1	keratin 1 [Source:HGNC Symbol;Acc:HGNC:6412]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045095//keratin filament;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0030280//structural constituent of skin epidermis;GO:0038023//signaling receptor activity;GO:0046982//protein heterodimerization activity	"GO:0001867//complement activation, lectin pathway;GO:0001895//retina homeostasis;GO:0006979//response to oxidative stress;GO:0018149//peptide cross-linking;GO:0042730//fibrinolysis;GO:0045765//regulation of angiogenesis;GO:0050728//negative regulation of inflammatory response;GO:0051290//protein heterotetramerization;GO:0061436//establishment of skin barrier"	--
ENSG00000167769	0.068	0.101	0	0.228	0.04	0.278	2	3	0	5	1	6	ACER1	alkaline ceramidase 1 [Source:HGNC Symbol;Acc:HGNC:18356]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K01441;K01441;K01441	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0046872//metal ion binding;GO:0071633//dihydroceramidase activity;GO:0102121//ceramidase activity"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0008544//epidermis development;GO:0010446//response to alkaline pH;GO:0019216//regulation of lipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0033561//regulation of water loss via skin;GO:0046512//sphingosine biosynthetic process;GO:0046514//ceramide catabolic process;GO:0048733//sebaceous gland development;GO:0071277//cellular response to calcium ion	--
ENSG00000167770	42.467	46.122	47.184	53.864	46.598	45.288	1458	1555.87	1165	1328	1299	1120	OTUB1	"OTU deubiquitinase, ubiquitin aldehyde binding 1 [Source:HGNC Symbol;Acc:HGNC:23077]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019784//NEDD8-specific protease activity;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0016579//protein deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:2000780//negative regulation of double-strand break repair	--
ENSG00000167771	0.628	0.609	0.717	1.072	0.548	0.409	38	37	32	48	28	18	RCOR2	REST corepressor 2 [Source:HGNC Symbol;Acc:HGNC:27455]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019899//enzyme binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated"	MYB
ENSG00000167772	1.165	1.605	1.69	1.085	1.934	0.855	44	61	48	25	62	23	ANGPTL4	angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	ko03320//PPAR signaling pathway;ko04979//Cholesterol metabolism	K08767;K08767	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0072562//blood microparticle	GO:0004857//enzyme inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0006629//lipid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043335//protein unfolding;GO:0045766//positive regulation of angiogenesis;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0070328//triglyceride homeostasis;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000167774	10.231	20.655	9.497	14.389	15.198	8.441	123.08	249.77	84.38	128.22	154.47	73.89	NDUFA7	novel transcript	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951	-	-	-	--
ENSG00000167775	36.864	40.752	39.379	38.619	37.325	36.389	956	1056	750	738	813	683	CD320	CD320 molecule [Source:HGNC Symbol;Acc:HGNC:16692]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0031419//cobalamin binding;GO:0038024//cargo receptor activity;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0009235//cobalamin metabolic process;GO:0015889//cobalamin transport;GO:0030656//regulation of vitamin metabolic process;GO:0030890//positive regulation of B cell proliferation;GO:0031296//B cell costimulation	--
ENSG00000167778	21.3	21.186	24.94	28.655	23.95	23.688	1219	1211	1027	1216	1183	973	SPRYD3	SPRY domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25920]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000167779	8.868	8.047	10.785	7.596	6.809	4.973	175	148	136	111	113	68	IGFBP6	insulin like growth factor binding protein 6 [Source:HGNC Symbol;Acc:HGNC:5475]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0042568//insulin-like growth factor binary complex	GO:0001968//fibronectin binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0019838//growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0016477//cell migration;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000167780	0	0	0	0.036	0	0	0	0	0	1	0	0	SOAT2	sterol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:11178]	Organismal Systems;Metabolism	Digestive system;Lipid metabolism	ko04979//Cholesterol metabolism;ko00100//Steroid biosynthesis	K00637;K00637	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000062//fatty-acyl-CoA binding;GO:0004772//sterol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0015485//cholesterol binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0034736//cholesterol O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010742//macrophage derived foam cell differentiation;GO:0030299//intestinal cholesterol absorption;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034383//low-density lipoprotein particle clearance;GO:0034435//cholesterol esterification;GO:0042632//cholesterol homeostasis	--
ENSG00000167785	3.278	3.527	2.809	2.353	2.945	2.748	244	264	157	143	179	145	ZNF558	zinc finger protein 558 [Source:HGNC Symbol;Acc:HGNC:26422]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000167791	0	0	0	0	0	0	0	0	0	0	0	0	CABP2	calcium binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1385]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0050896//response to stimulus	--
ENSG00000167792	65.783	65.875	70.06	89.005	77.739	83.315	2060	2116	1635	2123	2140	1953	NDUFV1	NADH:ubiquinone oxidoreductase core subunit V1 [Source:HGNC Symbol;Acc:HGNC:7716]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942;K03942	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005829//cytosol;GO:0016020//membrane;GO:0045271//respiratory chain complex I;GO:0070469//respirasome	"GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051287//NAD binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000167797	21.88	22.247	21.205	20.798	28.463	18.784	413	422	295	290	452	258	CDK2AP2	cyclin dependent kinase 2 associated protein 2 [Source:HGNC Symbol;Acc:HGNC:30833]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule	GO:0005515//protein binding;GO:0016301//kinase activity	GO:0016310//phosphorylation;GO:0070507//regulation of microtubule cytoskeleton organization;GO:2000035//regulation of stem cell division;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000167799	2.635	1.996	3.855	2.578	2.145	2.224	41	31	44	30	28	25	NUDT8	nudix hydrolase 8 [Source:HGNC Symbol;Acc:HGNC:8055]	-	-	-	-	GO:0005739//mitochondrion	GO:0000287//magnesium ion binding;GO:0010945//CoA pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding	GO:0015938//coenzyme A catabolic process;GO:0036114//medium-chain fatty-acyl-CoA catabolic process;GO:0044580//butyryl-CoA catabolic process;GO:0046356//acetyl-CoA catabolic process;GO:1901289//succinyl-CoA catabolic process;GO:1902859//propionyl-CoA catabolic process;GO:2001294//malonyl-CoA catabolic process	--
ENSG00000167800	0.028	0.027	0	0	0	0	1	1	0	0	0	0	TBX10	T-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11593]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0001708//cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis"	T-box
ENSG00000167807	0.646	0.399	0.258	0.534	0.648	0.44	26.19	16.29	7.73	16.06	22.21	13	FDX2	novel transcript	-	-	-	-	-	"GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0140647//P450-containing electron transport chain	--
ENSG00000167815	152.248	167.612	185.742	184.3	178.609	164.839	2920	3231	2631	2616	2894	2298	PRDX2	peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353]	Cellular Processes	Cell growth and death	ko04214//Apoptosis - fly	K03386	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0051920//peroxiredoxin activity	GO:0002357//defense response to tumor cell;GO:0002536//respiratory burst involved in inflammatory response;GO:0006979//response to oxidative stress;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0019430//removal of superoxide radicals;GO:0030194//positive regulation of blood coagulation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032496//response to lipopolysaccharide;GO:0034599//cellular response to oxidative stress;GO:0042098//T cell proliferation;GO:0042743//hydrogen peroxide metabolic process;GO:0042744//hydrogen peroxide catabolic process;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045321//leukocyte activation;GO:0045454//cell redox homeostasis;GO:0045581//negative regulation of T cell differentiation;GO:0048538//thymus development;GO:0048872//homeostasis of number of cells;GO:0098869//cellular oxidant detoxification;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000167822	0	0	0	0	0	0	0	0	0	0	0	0	OR8J3	olfactory receptor family 8 subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:15312]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000167825	0	0	0	0	0	0	0	0	0	0	0	0	OR5I1	olfactory receptor family 5 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:8347]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000167840	6.021	6.674	7.141	5.459	4.965	8.045	197	215	166	139	129	184	ZNF232	zinc finger protein 232 [Source:HGNC Symbol;Acc:HGNC:13026]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000167842	7.496	7.746	7.508	6.832	7.798	7.046	351	365	260	235	296	246	MIS12	MIS12 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:24967]	-	-	-	-	"GO:0000444//MIS12/MIND type complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000818//nuclear MIS12/MIND complex;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005829//cytosol;GO:0031617//NMS complex"	GO:0005515//protein binding	GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0034501//protein localization to kinetochore;GO:0051301//cell division;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0051382//kinetochore assembly	--
ENSG00000167850	0	0	0	0	0.037	0	0	0	0	0	1	0	CD300C	CD300c molecule [Source:HGNC Symbol;Acc:HGNC:19320]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0006968//cellular defense response	--
ENSG00000167851	0.37	0.311	0.112	0.121	0.354	0.412	9	11	2	3	5	8	CD300A	CD300a molecule [Source:HGNC Symbol;Acc:HGNC:19319]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0001786//phosphatidylserine binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0008429//phosphatidylethanolamine binding;GO:0038023//signaling receptor activity	"GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0030889//negative regulation of B cell proliferation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0034125//negative regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0043305//negative regulation of mast cell degranulation;GO:0043407//negative regulation of MAP kinase activity;GO:0048147//negative regulation of fibroblast proliferation;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0051134//negative regulation of NK T cell activation;GO:0060101//negative regulation of phagocytosis, engulfment;GO:1902564//negative regulation of neutrophil activation;GO:1902567//negative regulation of eosinophil activation;GO:1902569//negative regulation of activation of Janus kinase activity;GO:2000417//negative regulation of eosinophil migration"	--
ENSG00000167858	0.555	0.461	0.369	0.019	0.067	0.135	39	22	18	1	4	5	TEKT1	tektin 1 [Source:HGNC Symbol;Acc:HGNC:15534]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility	--
ENSG00000167861	11.051	13.155	11.223	10.815	12.767	10.785	756	861	567	548	717	490	HID1	HID1 domain containing [Source:HGNC Symbol;Acc:HGNC:15736]	-	-	-	-	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0090498//extrinsic component of Golgi membrane	GO:0005515//protein binding	-	--
ENSG00000167862	8.419	8.853	8.251	8.372	8.107	7.634	154	165	113	115	127	103	MRPL58	mitochondrial ribosomal protein L58 [Source:HGNC Symbol;Acc:HGNC:5359]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0005886//plasma membrane	"GO:0003747//translation release factor activity;GO:0004045//aminoacyl-tRNA hydrolase activity;GO:0016150//translation release factor activity, codon nonspecific;GO:0016787//hydrolase activity"	GO:0006412//translation;GO:0006415//translational termination;GO:0032543//mitochondrial translation;GO:0070126//mitochondrial translational termination	--
ENSG00000167863	78.848	85.729	87.694	86.917	82.659	79.891	996	1088	818	813	882	734	ATP5PD	ATP synthase peripheral stalk subunit d [Source:HGNC Symbol;Acc:HGNC:845]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02138;K02138;K02138;K02138;K02138;K02138;K02138;K02138;K02138;K02138;K02138	"GO:0000274//mitochondrial proton-transporting ATP synthase, stator stalk;GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000167874	17.221	16.776	21.98	35.98	27.556	31.393	303	293	279	451	403	396	TMEM88	transmembrane protein 88 [Source:HGNC Symbol;Acc:HGNC:32371]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030165//PDZ domain binding	GO:0016055//Wnt signaling pathway;GO:0050821//protein stabilization;GO:0072659//protein localization to plasma membrane;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000167880	0.015	0.008	0	0	0.073	0.011	2	1	0	0	8	1	EVPL	envoplakin [Source:HGNC Symbol;Acc:HGNC:3503]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0030054//cell junction;GO:0030057//desmosome;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019215//intermediate filament binding;GO:0045296//cadherin binding	GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization;GO:0042060//wound healing;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000167881	25.843	27.483	27.513	21.82	24.373	23.237	1359	1457	1054	909	1066	928	SRP68	signal recognition particle 68 [Source:HGNC Symbol;Acc:HGNC:11302]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03107	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0048500//signal recognition particle"	GO:0003723//RNA binding;GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0008312//7S RNA binding;GO:0019904//protein domain specific binding;GO:0030942//endoplasmic reticulum signal peptide binding;GO:0043022//ribosome binding	GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0009410//response to xenobiotic stimulus	--
ENSG00000167889	0.016	0.053	0.089	0.067	0.078	0	1	5	4	3	4	0	MGAT5B	"alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B [Source:HGNC Symbol;Acc:HGNC:24140]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00515//Mannose type O-glycan biosynthesis	K09661;K09661;K09661	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018242//protein O-linked glycosylation via serine	--
ENSG00000167895	0.025	0.037	0.017	0.116	0.087	0.067	2	3	1	7	6	4	TMC8	transmembrane channel like 8 [Source:HGNC Symbol;Acc:HGNC:20474]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008381//mechanosensitive ion channel activity;GO:0043120//tumor necrosis factor binding;GO:0140311//protein sequestering activity	GO:0001558//regulation of cell growth;GO:0006811//ion transport;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0034220//ion transmembrane transport;GO:0055069//zinc ion homeostasis;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000167900	3.032	3.478	2.473	2.377	1.969	2.269	86	100	54	48	51	46	TK1	thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00857;K00857;K00857	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004797//thymidine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006139//nucleobase-containing compound metabolic process;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0016310//phosphorylation;GO:0046104//thymidine metabolic process;GO:0051289//protein homotetramerization;GO:0071897//DNA biosynthetic process	--
ENSG00000167904	11.252	10.275	13.824	10.699	10.117	10.6	447	381	352	336	313	327	TMEM68	transmembrane protein 68 [Source:HGNC Symbol;Acc:HGNC:26510]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016746//acyltransferase activity	GO:0006650//glycerophospholipid metabolic process	--
ENSG00000167910	0	0.033	0	0.023	0	0	0	2	0	1	0	0	CYP7A1	cytochrome P450 family 7 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2651]	Metabolism;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Endocrine system;Lipid metabolism;Digestive system;Lipid metabolism	ko01100//Metabolic pathways;ko04976//Bile secretion;ko03320//PPAR signaling pathway;ko00140//Steroid hormone biosynthesis;ko04979//Cholesterol metabolism;ko00120//Primary bile acid biosynthesis	K00489;K00489;K00489;K00489;K00489;K00489	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008123//cholesterol 7-alpha-monooxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0033782//24-hydroxycholesterol 7alpha-hydroxylase activity;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006707//cholesterol catabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010468//regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0015721//bile acid and bile salt transport;GO:0016125//sterol metabolic process;GO:0032966//negative regulation of collagen biosynthetic process;GO:0038183//bile acid signaling pathway;GO:0042632//cholesterol homeostasis;GO:0045471//response to ethanol;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0070857//regulation of bile acid biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0071397//cellular response to cholesterol	--
ENSG00000167914	0	0	0	0	0	0	0	0	0	0	0	0	GSDMA	gasdermin A [Source:HGNC Symbol;Acc:HGNC:13311]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	"GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding"	GO:0006915//apoptotic process;GO:0012501//programmed cell death;GO:0042742//defense response to bacterium;GO:0070269//pyroptosis	--
ENSG00000167916	0	0	0	0	0	0	0	0	0	0	0	0	KRT24	keratin 24 [Source:HGNC Symbol;Acc:HGNC:18527]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000167925	6.256	6.062	8.354	9.061	7.908	7.636	313	304	264	310	334	272	GHDC	GH3 domain containing [Source:HGNC Symbol;Acc:HGNC:24438]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0035580//specific granule lumen	GO:0003674//molecular_function;GO:0016881//acid-amino acid ligase activity	GO:0008150//biological_process	--
ENSG00000167930	79.367	74.058	74.785	83.006	81.953	74.71	3731.16	3823	2779.61	3174.35	3460.88	2710	FAM234A	family with sequence similarity 234 member A [Source:HGNC Symbol;Acc:HGNC:14163]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000167941	0	0	0.028	0	0	0	0	0	1	0	0	0	SOST	sclerostin [Source:HGNC Symbol;Acc:HGNC:13771]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	"ko04310//Wnt signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action"	K16834;K16834	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0032991//protein-containing complex;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0036122//BMP binding;GO:0140297//DNA-binding transcription factor binding	"GO:0001503//ossification;GO:0009612//response to mechanical stimulus;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030279//negative regulation of ossification;GO:0030514//negative regulation of BMP signaling pathway;GO:0031333//negative regulation of protein-containing complex assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000167962	6.454	4.489	6.647	6.591	6.549	7.535	432	315	300	331	342	368	ZNF598	"zinc finger protein 598, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:28079]"	-	-	-	-	-	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0072344//rescue of stalled ribosome	--
ENSG00000167964	5.575	5.208	6.59	9.475	6.425	7.719	186	170	169	230	180	195	RAB26	"RAB26, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14259]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031226//intrinsic component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019002//GMP binding	"GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0035272//exocrine system development;GO:0043001//Golgi to plasma membrane protein transport;GO:0045055//regulated exocytosis;GO:0099575//regulation of protein catabolic process at presynapse, modulating synaptic transmission"	--
ENSG00000167965	31.992	36.402	37.159	40.845	39.238	44.14	1008	1141	863	987	999	992	MLST8	"MTOR associated protein, LST8 homolog [Source:HGNC Symbol;Acc:HGNC:24825]"	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Environmental adaptation;Signal transduction;Transport and catabolism;Transport and catabolism	ko04151//PI3K-Akt signaling pathway;ko04714//Thermogenesis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04136//Autophagy - other	K08266;K08266;K08266;K08266;K08266	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex	GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0006974//cellular response to DNA damage stimulus;GO:0007010//cytoskeleton organization;GO:0010507//negative regulation of autophagy;GO:0016310//phosphorylation;GO:0030307//positive regulation of cell growth;GO:0030838//positive regulation of actin filament polymerization;GO:0031669//cellular response to nutrient levels;GO:0031929//TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0032956//regulation of actin cytoskeleton organization;GO:0038202//TORC1 signaling;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0045821//positive regulation of glycolytic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071456//cellular response to hypoxia;GO:0071470//cellular response to osmotic stress;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1905857//positive regulation of pentose-phosphate shunt	--
ENSG00000167967	6.013	5.905	5.622	5.581	6.688	7.055	299	308	211	214	277	241	E4F1	E4F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3121]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0035497//cAMP response element binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006260//DNA replication;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0010564//regulation of cell cycle process;GO:0016567//protein ubiquitination;GO:0040008//regulation of growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051301//cell division;GO:0051726//regulation of cell cycle"	zf-C2H2
ENSG00000167968	0.118	0.251	0.089	0.03	0.156	0.03	3	8	3	1	6	1	DNASE1L2	deoxyribonuclease 1 like 2 [Source:HGNC Symbol;Acc:HGNC:2958]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004530//deoxyribonuclease I activity;GO:0004536//deoxyribonuclease activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0001942//hair follicle development;GO:0003335//corneocyte development;GO:0006259//DNA metabolic process;GO:0006308//DNA catabolic process"	--
ENSG00000167969	32.995	32.851	36.815	42.736	39.497	41.612	871	876	727	819	881	760	ECI1	enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703]	Metabolism	Lipid metabolism	ko00071//Fatty acid degradation	K13238	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003824//catalytic activity;GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0016853//isomerase activity;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000167971	1.739	1.7	1.676	2.137	2.13	2.051	210.62	207.01	149.93	191.68	217.99	180.7	CASKIN1	CASK interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20879]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction	--
ENSG00000167972	13.317	13.745	13.739	12.072	16.041	12.033	1822	1888	1386	1220	1749	1197	ABCA3	ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05643	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0042599//lamellar body;GO:0043231//intracellular membrane-bounded organelle;GO:0097208//alveolar lamellar body;GO:0097232//lamellar body membrane;GO:0097233//alveolar lamellar body membrane	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0008559//ABC-type xenobiotic transporter activity;GO:0016887//ATP hydrolysis activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0120019//phosphatidylcholine transfer activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140345//phosphatidylcholine flippase activity;GO:0140359//ABC-type transporter activity	GO:0006855//xenobiotic transmembrane transport;GO:0006869//lipid transport;GO:0009410//response to xenobiotic stimulus;GO:0010875//positive regulation of cholesterol efflux;GO:0015914//phospholipid transport;GO:0030324//lung development;GO:0032368//regulation of lipid transport;GO:0032464//positive regulation of protein homooligomerization;GO:0034204//lipid translocation;GO:0042908//xenobiotic transport;GO:0043129//surfactant homeostasis;GO:0044267//cellular protein metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0046618//xenobiotic export;GO:0046890//regulation of lipid biosynthetic process;GO:0051384//response to glucocorticoid;GO:0055085//transmembrane transport;GO:0055091//phospholipid homeostasis;GO:0070925//organelle assembly;GO:0120009//intermembrane lipid transfer;GO:0150172//regulation of phosphatidylcholine metabolic process;GO:1902995//positive regulation of phospholipid efflux;GO:2001140//positive regulation of phospholipid transport	--
ENSG00000167977	12.162	11.114	12.364	11.632	10.949	11.869	614	564	461	435	467	436	KCTD5	potassium channel tetramerization domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21423]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0097602//cullin family protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051260//protein homooligomerization	--
ENSG00000167978	58.569	59.931	62.457	58.362	68.5	64.304	10140	10690	8246	7577	9819	8220	SRRM2	serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:HGNC:16639]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0070742//C2H2 zinc finger domain binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000167981	0.853	0.805	0.738	0.736	0.687	0.798	97	92	62	62	66	66	ZNF597	zinc finger protein 597 [Source:HGNC Symbol;Acc:HGNC:26573]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000167984	0.188	0.18	0.153	0.152	0.249	0.176	25	24	15	15	28	17	NLRC3	NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding	GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032687//negative regulation of interferon-alpha production;GO:0032688//negative regulation of interferon-beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045824//negative regulation of innate immune response;GO:0048147//negative regulation of fibroblast proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000167985	17.408	19.522	16.308	16.748	16.315	19.516	404.49	453.11	282.66	294.2	327.23	321.6	SDHAF2	succinate dehydrogenase complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:26034]	-	-	-	-	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0006099//tricarboxylic acid cycle;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0006470//protein dephosphorylation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0018293//protein-FAD linkage;GO:0034553//mitochondrial respiratory chain complex II assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000167986	96.236	102.462	104.847	101.638	101.034	95.234	8409	9039	6803	6594	7497	6085	DDB1	damage specific DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2717]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Infectious disease: viral;Cancer: overview;Infectious disease: viral;Folding, sorting and degradation;Replication and repair"	ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04120//Ubiquitin mediated proteolysis;ko03420//Nucleotide excision repair	K10610;K10610;K10610;K10610;K10610	"GO:0000781//chromosome, telomeric region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0032991//protein-containing complex;GO:0035861//site of double-strand break;GO:0070062//extracellular exosome;GO:0080008//Cul4-RING E3 ubiquitin ligase complex"	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0044877//protein-containing complex binding;GO:0071987//WD40-repeat domain binding;GO:0097602//cullin family protein binding	GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010498//proteasomal protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0019076//viral release from host cell;GO:0034644//cellular response to UV;GO:0035518//histone H2A monoubiquitination;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045070//positive regulation of viral genome replication;GO:0045722//positive regulation of gluconeogenesis;GO:0045732//positive regulation of protein catabolic process;GO:0046726//positive regulation by virus of viral protein levels in host cell;GO:0048511//rhythmic process;GO:0051702//biological process involved in interaction with symbiont;GO:0070914//UV-damage excision repair;GO:1901990//regulation of mitotic cell cycle phase transition	--
ENSG00000167987	9.093	7.842	8.425	8.872	8.347	7.908	468	392	345	332	391	319	VPS37C	VPS37C subunit of ESCRT-I [Source:HGNC Symbol;Acc:HGNC:26097]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12185	GO:0000813//ESCRT I complex;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043657//host cell;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	GO:0006612//protein targeting to membrane;GO:0006623//protein targeting to vacuole;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046907//intracellular transport;GO:0075733//intracellular transport of virus	--
ENSG00000167992	0.072	0.081	0.055	0.193	0.119	0.131	3	6	3	10	7	7	VWCE	von Willebrand factor C and EGF domains [Source:HGNC Symbol;Acc:HGNC:26487]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0098586//cellular response to virus	--
ENSG00000167994	14.687	13.561	13.99	18.087	15.993	19.449	704	652	495	641	644	680	RAB3IL1	RAB3A interacting protein like 1 [Source:HGNC Symbol;Acc:HGNC:9780]	-	-	-	-	GO:0005829//cytosol;GO:0070319//Golgi to plasma membrane transport vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006887//exocytosis;GO:0015031//protein transport;GO:0050790//regulation of catalytic activity	--
ENSG00000167995	761.533	796.714	864.242	981.199	981.797	965.704	44713.43	46769.08	37442.7	41725.96	47641.88	41392.32	BEST1	bestrophin 1 [Source:HGNC Symbol;Acc:HGNC:12703]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0034707//chloride channel complex	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007601//visual perception;GO:0015701//bicarbonate transport;GO:0030321//transepithelial chloride transport;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0051924//regulation of calcium ion transport;GO:1902476//chloride transmembrane transport	--
ENSG00000167996	1805.94	1810.867	1945.173	1970.153	1645.28	1663.147	34366.57	35164.92	26463.3	25641.04	26415.12	22357.68	FTH1	ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976]	Cellular Processes;Organismal Systems;Cellular Processes	Cell growth and death;Digestive system;Cell growth and death	ko04217//Necroptosis;ko04978//Mineral absorption;ko04216//Ferroptosis	K00522;K00522;K00522	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008043//intracellular ferritin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044754//autolysosome;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004322//ferroxidase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006880//intracellular sequestering of iron ion;GO:0006955//immune response;GO:0008285//negative regulation of cell population proliferation;GO:0048147//negative regulation of fibroblast proliferation	--
ENSG00000168000	38.161	39.154	43.437	48.93	45.592	49.683	1218.83	1204.63	1000.64	1161.7	1191.41	1093.81	BSCL2	"BSCL2 lipid droplet biogenesis associated, seipin [Source:HGNC Symbol;Acc:HGNC:15832]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019915//lipid storage;GO:0034389//lipid droplet organization;GO:0045444//fat cell differentiation;GO:0050995//negative regulation of lipid catabolic process;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0140042//lipid droplet formation	--
ENSG00000168002	50.363	54.07	55.564	55.579	51.78	48.199	832	902	683	672	726	574	POLR2G	RNA polymerase II subunit G [Source:HGNC Symbol;Acc:HGNC:9194]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03015;K03015	"GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex"	GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	"GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0006351//transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045948//positive regulation of translational initiation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"	--
ENSG00000168003	276.143	292.137	315.27	457.796	407.098	465.029	10577	11636	9212	13338	13566	13379	SLC3A2	solute carrier family 3 member 2 [Source:HGNC Symbol;Acc:HGNC:11026]	Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Digestive system;Cell growth and death	ko04150//mTOR signaling pathway;ko04974//Protein digestion and absorption;ko04216//Ferroptosis	K06519;K06519;K06519	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0044225//apical pole of neuron;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:1990184//amino acid transport complex	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003824//catalytic activity;GO:0005432//calcium:sodium antiporter activity;GO:0005515//protein binding;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0045296//cadherin binding	GO:0005975//carbohydrate metabolic process;GO:0006816//calcium ion transport;GO:0006865//amino acid transport;GO:0015820//leucine transport;GO:0015823//phenylalanine transport;GO:0015827//tryptophan transport;GO:0035725//sodium ion transmembrane transport;GO:0043330//response to exogenous dsRNA;GO:0046718//viral entry into host cell;GO:0098713//leucine import across plasma membrane;GO:1903801//L-leucine import across plasma membrane;GO:1904273//L-alanine import across plasma membrane	--
ENSG00000168004	0.625	0.69	0.628	0.996	0.535	0.943	31	40	25	38	27	37	PLAAT5	phospholipase A and acyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:24978]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008970//phospholipase A1 activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process	--
ENSG00000168005	8.846	9.06	8.837	9.11	9.776	8.459	356	351	262	271	327	237	SPINDOC	spindlin interactor and repressor of chromatin binding [Source:HGNC Symbol;Acc:HGNC:25115]	-	-	-	-	-	GO:0005515//protein binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000168010	1.823	1.706	2.403	1.003	2.093	1.9	69.71	59.13	64	38.01	75	49	ATG16L2	autophagy related 16 like 2 [Source:HGNC Symbol;Acc:HGNC:25464]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K20868	GO:0000421//autophagosome membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034045//phagophore assembly site membrane;GO:0034274//Atg12-Atg5-Atg16 complex	GO:0005515//protein binding	GO:0000045//autophagosome assembly;GO:0006497//protein lipidation;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0039689//negative stranded viral RNA replication	--
ENSG00000168014	5.796	5.79	5.254	4.729	4.571	5.864	721.83	678.5	494.89	386.61	476.32	465.02	C2CD3	C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001947//heart looping;GO:0007389//pattern specification process;GO:0007420//brain development;GO:0008589//regulation of smoothened signaling pathway;GO:0016485//protein processing;GO:0021915//neural tube development;GO:0021997//neural plate axis specification;GO:0030030//cell projection organization;GO:0030162//regulation of proteolysis;GO:0030326//embryonic limb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0060271//cilium assembly;GO:0061511//centriole elongation;GO:0071539//protein localization to centrosome;GO:1905515//non-motile cilium assembly	--
ENSG00000168016	1.66	1.646	4.066	1.53	1.882	2.476	357	358	218	248	345	238	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:29011]	-	-	-	-	-	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030544//Hsp70 protein binding;GO:0051879//Hsp90 protein binding	GO:0006457//protein folding	--
ENSG00000168026	0.488	0.456	0.713	0.325	0.539	0.535	42	40	46	21	38	34	TTC21A	tetratricopeptide repeat domain 21A [Source:HGNC Symbol;Acc:HGNC:30761]	-	-	-	-	GO:0005929//cilium;GO:0030991//intraciliary transport particle A	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0035721//intraciliary retrograde transport;GO:0061512//protein localization to cilium	--
ENSG00000168028	421.117	454.661	437.928	465.677	406.9	406.91	9061.31	9895.66	6949.86	7530.54	7452.57	6424.11	RPSA	ribosomal protein SA [Source:HGNC Symbol;Acc:HGNC:6502]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02998;K02998	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001618//virus receptor activity;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005055//laminin receptor activity;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0043236//laminin binding	GO:0000028//ribosomal small subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0007155//cell adhesion;GO:0046718//viral entry into host cell	--
ENSG00000168032	3.191	3.945	2.597	2.21	3.004	2.454	193	216	116	99	143	108	ENTPD3	ectonucleoside triphosphate diphosphohydrolase 3 [Source:HGNC Symbol;Acc:HGNC:3365]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Infectious disease: viral;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko05169//Epstein-Barr virus infection;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01510;K01510;K01510;K01510	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:0102485//dATP phosphohydrolase activity;GO:0102486//dCTP phosphohydrolase activity;GO:0102487//dUTP phosphohydrolase activity;GO:0102488//dTTP phosphohydrolase activity;GO:0102489//GTP phosphohydrolase activity;GO:0102490//8-oxo-dGTP phosphohydrolase activity;GO:0102491//dGTP phosphohydrolase activity	GO:0009134//nucleoside diphosphate catabolic process;GO:0009143//nucleoside triphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process	--
ENSG00000168036	81.852	86.099	87.05	62.353	66.667	71.788	5266	5475	4108	2908	3593	3334	CTNNB1	catenin beta 1 [Source:HGNC Symbol;Acc:HGNC:2514]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cancer: overview;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Cancer: specific types;Infectious disease: viral;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine and metabolic disease;Cardiovascular disease;Endocrine system;Immune system;Endocrine system;Cancer: specific types;Cancer: specific types;Infectious disease: bacterial;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05132//Salmonella infection;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko05418//Fluid shear stress and atherosclerosis;ko04919//Thyroid hormone signaling pathway;ko04670//Leukocyte transendothelial migration;ko04916//Melanogenesis;ko05215//Prostate cancer;ko05210//Colorectal cancer;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer;ko05216//Thyroid cancer	K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105;K02105	"GO:0000791//euchromatin;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005916//fascia adherens;GO:0005923//bicellular tight junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0016342//catenin complex;GO:0016600//flotillin complex;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030877//beta-catenin destruction complex;GO:0031253//cell projection membrane;GO:0031528//microvillus membrane;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0034750//Scrib-APC-beta-catenin complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043296//apical junction complex;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0070369//beta-catenin-TCF7L2 complex;GO:0071944//cell periphery;GO:0090575//RNA polymerase II transcription regulator complex;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098831//presynaptic active zone cytoplasmic component;GO:0099092//postsynaptic density, intracellular component;GO:1990711//beta-catenin-ICAT complex;GO:1990907//beta-catenin-TCF complex;GO:1990909//Wnt signalosome"	GO:0001221//transcription coregulator binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0030331//estrogen receptor binding;GO:0044325//transmembrane transporter binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0046332//SMAD binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070411//I-SMAD binding;GO:0097718//disordered domain specific binding;GO:0140297//DNA-binding transcription factor binding;GO:1990226//histone methyltransferase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0000578//embryonic axis specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0001501//skeletal system development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001701//in utero embryonic development;GO:0001702//gastrulation with mouth forming second;GO:0001706//endoderm formation;GO:0001708//cell fate specification;GO:0001709//cell fate determination;GO:0001711//endodermal cell fate commitment;GO:0001764//neuron migration;GO:0001822//kidney development;GO:0001837//epithelial to mesenchymal transition;GO:0001840//neural plate development;GO:0001894//tissue homeostasis;GO:0001944//vasculature development;GO:0002052//positive regulation of neuroblast proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002089//lens morphogenesis in camera-type eye;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0003338//metanephros morphogenesis;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007268//chemical synaptic transmission;GO:0007398//ectoderm development;GO:0007399//nervous system development;GO:0007403//glial cell fate determination;GO:0007507//heart development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009948//anterior/posterior axis specification;GO:0009950//dorsal/ventral axis specification;GO:0009953//dorsal/ventral pattern formation;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010909//positive regulation of heparan sulfate proteoglycan biosynthetic process;GO:0016055//Wnt signaling pathway;GO:0016331//morphogenesis of embryonic epithelium;GO:0016525//negative regulation of angiogenesis;GO:0019827//stem cell population maintenance;GO:0021819//layer formation in cerebral cortex;GO:0022009//central nervous system vasculogenesis;GO:0022405//hair cycle process;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0030316//osteoclast differentiation;GO:0030324//lung development;GO:0030539//male genitalia development;GO:0030856//regulation of epithelial cell differentiation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0030900//forebrain development;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0030997//regulation of centriole-centriole cohesion;GO:0031016//pancreas development;GO:0031069//hair follicle morphogenesis;GO:0031641//regulation of myelination;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032355//response to estradiol;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033077//T cell differentiation in thymus;GO:0033234//negative regulation of protein sumoylation;GO:0034332//adherens junction organization;GO:0034333//adherens junction assembly;GO:0034394//protein localization to cell surface;GO:0034613//cellular protein localization;GO:0035050//embryonic heart tube development;GO:0035112//genitalia morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0035315//hair cell differentiation;GO:0035995//detection of muscle stretch;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0036520//astrocyte-dopaminergic neuron signaling;GO:0042127//regulation of cell population proliferation;GO:0042129//regulation of T cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042733//embryonic digit morphogenesis;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0043525//positive regulation of neuron apoptotic process;GO:0043588//skin development;GO:0044093//positive regulation of molecular function;GO:0044334//canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0044338//canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0044339//canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0045453//bone resorption;GO:0045595//regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045667//regulation of osteoblast differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0045765//regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045976//negative regulation of mitotic cell cycle, embryonic;GO:0048145//regulation of fibroblast proliferation;GO:0048469//cell maturation;GO:0048489//synaptic vesicle transport;GO:0048513//animal organ development;GO:0048538//thymus development;GO:0048568//embryonic organ development;GO:0048599//oocyte development;GO:0048617//embryonic foregut morphogenesis;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048660//regulation of smooth muscle cell proliferation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0050767//regulation of neurogenesis;GO:0050768//negative regulation of neurogenesis;GO:0050808//synapse organization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051145//smooth muscle cell differentiation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051884//regulation of timing of anagen;GO:0051973//positive regulation of telomerase activity;GO:0060066//oviduct development;GO:0060070//canonical Wnt signaling pathway;GO:0060173//limb development;GO:0060439//trachea morphogenesis;GO:0060440//trachea formation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060479//lung cell differentiation;GO:0060484//lung-associated mesenchyme development;GO:0060492//lung induction;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0060769//positive regulation of epithelial cell proliferation involved in prostate gland development;GO:0060789//hair follicle placode formation;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0061047//positive regulation of branching involved in lung morphogenesis;GO:0061154//endothelial tube morphogenesis;GO:0061198//fungiform papilla formation;GO:0061324//canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation;GO:0061549//sympathetic ganglion development;GO:0061550//cranial ganglion development;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0071363//cellular response to growth factor stimulus;GO:0071681//cellular response to indole-3-methanol;GO:0072033//renal vesicle formation;GO:0072053//renal inner medulla development;GO:0072054//renal outer medulla development;GO:0072079//nephron tubule formation;GO:0072182//regulation of nephron tubule epithelial cell differentiation;GO:0072497//mesenchymal stem cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090279//regulation of calcium ion import;GO:0097091//synaptic vesicle clustering;GO:0098609//cell-cell adhesion;GO:1901215//negative regulation of neuron death;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:1904796//regulation of core promoter binding;GO:1904798//positive regulation of core promoter binding;GO:1904888//cranial skeletal system development;GO:1904948//midbrain dopaminergic neuron differentiation;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:1990138//neuron projection extension;GO:1990403//embryonic brain development;GO:1990791//dorsal root ganglion development;GO:2000008//regulation of protein localization to cell surface;GO:2000017//positive regulation of determination of dorsal identity;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000168038	2.481	3.31	1.752	1.628	1.262	1.929	206	216	107	100	95	125	ULK4	unc-51 like kinase 4 [Source:HGNC Symbol;Acc:HGNC:15784]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0010975//regulation of neuron projection development;GO:0016310//phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0046328//regulation of JNK cascade;GO:0090036//regulation of protein kinase C signaling;GO:1900744//regulation of p38MAPK cascade;GO:2001222//regulation of neuron migration	--
ENSG00000168040	11.319	11.682	13.071	11.927	11.861	11.677	401	416	342	313	355	301	FADD	Fas associated via death domain [Source:HGNC Symbol;Acc:HGNC:3573]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Signal transduction;Infectious disease: parasitic;Immune system;Immune system;Drug resistance: antineoplastic;Immune system;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko04668//TNF signaling pathway;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko01524//Platinum drug resistance;ko04622//RIG-I-like receptor signaling pathway;ko04215//Apoptosis - multiple species	K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373;K02373	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031264//death-inducing signaling complex;GO:0031265//CD95 death-inducing signaling complex;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045121//membrane raft;GO:0097342//ripoptosome	GO:0002020//protease binding;GO:0005123//death receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0033612//receptor serine/threonine kinase binding;GO:0035877//death effector domain binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0089720//caspase binding	"GO:0001822//kidney development;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002376//immune system process;GO:0002821//positive regulation of adaptive immune response;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0032729//positive regulation of interferon-gamma production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033077//T cell differentiation in thymus;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0042220//response to cocaine;GO:0042981//regulation of apoptotic process;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043278//response to morphine;GO:0045087//innate immune response;GO:0045651//positive regulation of macrophage differentiation;GO:0045862//positive regulation of proteolysis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048148//behavioral response to cocaine;GO:0048535//lymph node development;GO:0048536//spleen development;GO:0048538//thymus development;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060544//regulation of necroptotic process;GO:0060546//negative regulation of necroptotic process;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0071260//cellular response to mechanical stimulus;GO:0071550//death-inducing signaling complex assembly;GO:0097049//motor neuron apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0097527//necroptotic signaling pathway;GO:2000454//positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000168056	106.965	122.25	104.034	91.059	108.97	83.147	9703	11088.07	6927	6100	8259.5	5440	LTBP3	latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0050431//transforming growth factor beta binding	GO:0001501//skeletal system development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030502//negative regulation of bone mineralization;GO:0032331//negative regulation of chondrocyte differentiation;GO:0036363//transforming growth factor beta activation;GO:0045780//positive regulation of bone resorption;GO:0046849//bone remodeling;GO:0048251//elastic fiber assembly;GO:0060349//bone morphogenesis;GO:0060430//lung saccule development;GO:1902462//positive regulation of mesenchymal stem cell proliferation;GO:2000741//positive regulation of mesenchymal stem cell differentiation	--
ENSG00000168060	0.41	0.738	0.467	0.573	0.514	1.009	7	13	6	7	8	13	NAALADL1	N-acetylated alpha-linked acidic dipeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23536]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0004177//aminopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0043171//peptide catabolic process	--
ENSG00000168061	2.981	3.163	3.87	3.4	2.756	3.647	83	88	77	70	63	71	SAC3D1	SAC3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30179]	-	-	-	-	GO:0032991//protein-containing complex	-	-	--
ENSG00000168062	0.534	0.542	0.992	1.071	1.241	1.257	22	17	30	33	41	38	BATF2	basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163]	Human Diseases	Cancer: overview	ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K09034	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0042832//defense response to protozoan;GO:0043011//myeloid dendritic cell differentiation;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000168065	0	0	0	0	0	0	0	0	0	0	0	0	SLC22A11	solute carrier family 22 member 11 [Source:HGNC Symbol;Acc:HGNC:18120]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015698//inorganic anion transport;GO:0015711//organic anion transport;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport	--
ENSG00000168066	62.79	59.943	64.96	69.674	64.789	69.805	3484	3518	2771	2906	3207	2869	SF1	splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005840//ribosome;GO:0016604//nuclear body;GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0045131//pre-mRNA branch point binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0030238//male sex determination;GO:0030575//nuclear body organization;GO:0033327//Leydig cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050810//regulation of steroid biosynthetic process"	--
ENSG00000168067	4.858	4.925	5.201	5.732	7.116	5.686	392	355	309	312	435	284	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6864]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04414	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006903//vesicle targeting;GO:0006955//immune response;GO:0007254//JNK cascade;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043507//positive regulation of JUN kinase activity;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade	--
ENSG00000168070	0	0	0	0	0	0	0	0	0	0	0	0	MAJIN	membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005694//chromosome;GO:0016020//membrane;GO:0016021//integral component of membrane"	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0007129//homologous chromosome pairing at meiosis;GO:0045141//meiotic telomere clustering;GO:0051321//meiotic cell cycle;GO:0070197//meiotic attachment of telomere to nuclear envelope	--
ENSG00000168071	1.707	1.195	1.697	1.736	1.824	1.755	94	89	74	93	77	82	CCDC88B	coiled-coil domain containing 88B [Source:HGNC Symbol;Acc:HGNC:26757]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0051959//dynein light intermediate chain binding	GO:0001819//positive regulation of cytokine production;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization;GO:0042102//positive regulation of T cell proliferation;GO:0042832//defense response to protozoan;GO:0050870//positive regulation of T cell activation	--
ENSG00000168077	9.141	8.753	11.33	9.492	8.311	8.643	650	628	589	480	512	414	SCARA3	scavenger receptor class A member 3 [Source:HGNC Symbol;Acc:HGNC:19000]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005044//scavenger receptor activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0006979//response to oxidative stress;GO:0009650//UV protection	--
ENSG00000168078	0.191	0.323	0.533	0.252	0.51	0.539	7	12	15	5	13	11	PBK	PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0000278//mitotic cell cycle;GO:0001933//negative regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0034644//cellular response to UV;GO:0050728//negative regulation of inflammatory response	--
ENSG00000168079	0	0	0	0	0	0	0	0	0	0	0	0	SCARA5	scavenger receptor class A member 5 [Source:HGNC Symbol;Acc:HGNC:28701]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0070287//ferritin receptor activity	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006897//endocytosis;GO:0034605//cellular response to heat;GO:0034755//iron ion transmembrane transport;GO:0055072//iron ion homeostasis;GO:0070207//protein homotrimerization	--
ENSG00000168081	0.096	0	0	0	0	0	2	0	0	0	0	0	PNOC	prepronociceptin [Source:HGNC Symbol;Acc:HGNC:9163]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse	GO:0001515//opioid peptide activity;GO:0005184//neuropeptide hormone activity;GO:0031628//opioid receptor binding	GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007565//female pregnancy;GO:0007600//sensory perception	--
ENSG00000168090	48.106	52.049	48.519	49.383	49.459	58.798	1338	1426	1007	996	1192	1163	COPS6	COP9 signalosome subunit 6 [Source:HGNC Symbol;Acc:HGNC:21749]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0000338//protein deneddylation;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000168092	24.791	22.258	27.054	18.785	22.228	25.834	2000	1861	1420	1205	1449	1413	PAFAH1B2	platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:8575]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K16795;K16795	GO:0001650//fibrillar center;GO:0005576//extracellular region;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008247//1-alkyl-2-acetylglycerophosphocholine esterase complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0047179//platelet-activating factor acetyltransferase activity	GO:0006629//lipid metabolic process;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0016042//lipid catabolic process;GO:0016239//positive regulation of macroautophagy	--
ENSG00000168096	3.359	3.842	3.836	4.532	3.153	5.925	138	159	127	120	97	113	ANKS3	ankyrin repeat and sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29422]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000168101	23.515	26.545	26.757	29.19	26.376	28.178	664	751	553	609	625	577	NUDT16L1	nudix hydrolase 16 like 1 [Source:HGNC Symbol;Acc:HGNC:28154]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K16867	GO:0005634//nucleus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding	GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000168116	3.057	2.941	3.248	2.926	2.868	2.875	178	172	140	126	141	121	KIAA1586	KIAA1586 [Source:HGNC Symbol;Acc:HGNC:21360]	-	-	-	-	-	GO:0016740//transferase activity;GO:0061665//SUMO ligase activity	GO:0016925//protein sumoylation	--
ENSG00000168118	19.349	18.445	20.127	21.249	16.885	19.987	1198	1148	921	974	883	900	RAB4A	"RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9781]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07879	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031901//early endosome membrane;GO:0031982//vesicle;GO:0032593//insulin-responsive compartment;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0098837//postsynaptic recycling endosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0019882//antigen processing and presentation;GO:0030100//regulation of endocytosis;GO:0032482//Rab protein signal transduction	--
ENSG00000168124	0	0	0.069	0	0	0	0	0	1	0	0	0	OR1F1	olfactory receptor family 1 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:8194]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000168131	0	0	0	0	0	0	0	0	0	0	0	0	OR2B2	olfactory receptor family 2 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:13966]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000168135	2.125	2.555	2.782	3.751	3.62	4.556	91	110	88	119	131	142	KCNJ4	potassium inwardly rectifying channel subfamily J member 4 [Source:HGNC Symbol;Acc:HGNC:6265]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04921//Oxytocin signaling pathway;ko04725//Cholinergic synapse	K04998;K04998	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000168137	18.922	16.441	18.887	12.345	17.235	19.553	1828	1739	1360	1025	1359.01	1340	SETD5	SET domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25566]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016593//Cdc73/Paf1 complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0006325//chromatin organization;GO:0032259//methylation;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0035065//regulation of histone acetylation;GO:0050890//cognition;GO:0051567//histone H3-K9 methylation;GO:0051963//regulation of synapse assembly;GO:0097198//histone H3-K36 trimethylation;GO:1902275//regulation of chromatin organization"	--
ENSG00000168140	60.418	68.285	63.4	62.682	71.696	59.131	3529	4009	2735	2712	3538	2513	VASN	vasorin [Source:HGNC Symbol;Acc:HGNC:18517]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0050431//transforming growth factor beta binding	GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0071461//cellular response to redox state	--
ENSG00000168143	2.193	1.675	2.018	1.449	1.38	1.921	284	218	193	139	151	181	FAM83B	family with sequence similarity 83 member B [Source:HGNC Symbol;Acc:HGNC:21357]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding	GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008283//cell population proliferation	--
ENSG00000168148	0	0	0	0	0	0	0	0	0	0	0	0	H3-4	H3.4 histone [Source:HGNC Symbol;Acc:HGNC:4778]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	"GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly	--
ENSG00000168152	2.15	1.4	0.99	0.562	1.39	0.693	102	85	58	33	64	40	THAP9	THAP domain containing 9 [Source:HGNC Symbol;Acc:HGNC:23192]	-	-	-	-	-	GO:0003677//DNA binding;GO:0004803//transposase activity;GO:0016740//transferase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0006310//DNA recombination;GO:0006313//transposition, DNA-mediated;GO:0015074//DNA integration"	THAP
ENSG00000168158	0.136	0.271	0	0	0.04	0.187	4	8	0	0	1	4	OR2C1	olfactory receptor family 2 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8242]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000168159	33.955	36.166	38.522	42.834	39.422	32.301	2196	2351	1840	2052	2154	1520	RNF187	ring finger protein 187 [Source:HGNC Symbol;Acc:HGNC:27146]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051865//protein autoubiquitination;GO:0070936//protein K48-linked ubiquitination"	--
ENSG00000168172	3.11	1.857	1.012	0.68	1.098	2.025	407	312	211	150	276	210	HOOK3	hook microtubule tethering protein 3 [Source:HGNC Symbol;Acc:HGNC:23576]	-	-	-	-	GO:0000242//pericentriolar material;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030897//HOPS complex;GO:0034451//centriolar satellite;GO:0070695//FHF complex	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0034452//dynactin binding;GO:0042802//identical protein binding;GO:0045503//dynein light chain binding;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0022027//interkinetic nuclear migration;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization;GO:0034454//microtubule anchoring at centrosome;GO:0045022//early endosome to late endosome transport;GO:0050768//negative regulation of neurogenesis;GO:0051645//Golgi localization;GO:0071539//protein localization to centrosome;GO:0097150//neuronal stem cell population maintenance;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000168175	24.718	24.059	24.76	23.335	24.749	24.883	1629	1596	1204	1120	1370	1198	MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1 like [Source:HGNC Symbol;Acc:HGNC:19840]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000168209	37.444	34.878	36.867	48.175	43.213	49.839	1195	1134	885	1129	1169	1170	DDIT4	DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes	Signal transduction;Cancer: overview;Signal transduction;Transport and catabolism	ko04151//PI3K-Akt signaling pathway;ko05206//MicroRNAs in cancer;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal	K08270;K08270;K08270;K08270	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0071889//14-3-3 protein binding	GO:0001666//response to hypoxia;GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0007420//brain development;GO:0009968//negative regulation of signal transduction;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0030182//neuron differentiation;GO:0032006//regulation of TOR signaling;GO:0032007//negative regulation of TOR signaling;GO:0032984//protein-containing complex disassembly;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045820//negative regulation of glycolytic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051607//defense response to virus;GO:0071549//cellular response to dexamethasone stimulus;GO:0072593//reactive oxygen species metabolic process;GO:1901216//positive regulation of neuron death;GO:1902532//negative regulation of intracellular signal transduction	--
ENSG00000168214	18.111	16.276	16.263	20.422	13.383	14.309	1724	1473	948	928	1059	963	RBPJ	recombination signal binding protein for immunoglobulin kappa J region [Source:HGNC Symbol;Acc:HGNC:5724]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Immune system;Signal transduction	ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06053;K06053;K06053;K06053;K06053;K06053	GO:0000785//chromatin;GO:0002193//MAML1-RBP-Jkappa- ICN1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001756//somitogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001974//blood vessel remodeling;GO:0002437//inflammatory response to antigenic stimulus;GO:0003139//secondary heart field specification;GO:0003151//outflow tract morphogenesis;GO:0003157//endocardium development;GO:0003160//endocardium morphogenesis;GO:0003176//aortic valve development;GO:0003177//pulmonary valve development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0003214//cardiac left ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006959//humoral immune response;GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009912//auditory receptor cell fate commitment;GO:0009957//epidermal cell fate specification;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0021983//pituitary gland development;GO:0030097//hemopoiesis;GO:0030182//neuron differentiation;GO:0030183//B cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030279//negative regulation of ossification;GO:0030513//positive regulation of BMP signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0035912//dorsal aorta morphogenesis;GO:0036302//atrioventricular canal development;GO:0042127//regulation of cell population proliferation;GO:0042742//defense response to bacterium;GO:0043011//myeloid dendritic cell differentiation;GO:0045165//cell fate commitment;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048505//regulation of timing of cell differentiation;GO:0048733//sebaceous gland development;GO:0048820//hair follicle maturation;GO:0048844//artery morphogenesis;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060412//ventricular septum morphogenesis;GO:0060486//club cell differentiation;GO:0060716//labyrinthine layer blood vessel development;GO:0060844//arterial endothelial cell fate commitment;GO:0061314//Notch signaling involved in heart development;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0072554//blood vessel lumenization;GO:0097101//blood vessel endothelial cell fate specification;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1901186//positive regulation of ERBB signaling pathway;GO:1901189//positive regulation of ephrin receptor signaling pathway;GO:1901297//positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis"	CSL
ENSG00000168216	57.08	49.632	58.73	54.852	53.11	62.272	2405	2127	1824	1731	1909	1927	LMBRD1	LMBR1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23038]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14617	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005774//vacuolar membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045334//clathrin-coated endocytic vesicle	GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0031419//cobalamin binding;GO:0032050//clathrin heavy chain binding;GO:0035612//AP-2 adaptor complex binding;GO:0043495//protein-membrane adaptor activity	GO:0006897//endocytosis;GO:0007369//gastrulation;GO:0009235//cobalamin metabolic process;GO:0038016//insulin receptor internalization;GO:0061462//protein localization to lysosome;GO:0072583//clathrin-dependent endocytosis;GO:0072665//protein localization to vacuole	--
ENSG00000168228	3.053	2.637	2.673	2.428	2.911	2.29	171	142	111	100	130	94	ZCCHC4	zinc finger CCHC-type containing 4 [Source:HGNC Symbol;Acc:HGNC:22917]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0008988//rRNA (adenine-N6-)-methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:1904047//S-adenosyl-L-methionine binding	GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0045727//positive regulation of translation	--
ENSG00000168229	0	0	0	0	0	0	0	0	0	0	0	0	PTGDR	prostaglandin D2 receptor [Source:HGNC Symbol;Acc:HGNC:9591]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04332	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001785//prostaglandin J receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004956//prostaglandin D receptor activity;GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030238//male sex determination;GO:0030431//sleep;GO:0043303//mast cell degranulation;GO:0046085//adenosine metabolic process;GO:0071799//cellular response to prostaglandin D stimulus	--
ENSG00000168234	18.343	15.714	17.977	11.665	12.996	15.739	1269	1076	866	567	723	741	TTC39C	tetratricopeptide repeat domain 39C [Source:HGNC Symbol;Acc:HGNC:26595]	-	-	-	-	-	GO:0005515//protein binding	GO:0032474//otolith morphogenesis;GO:0060271//cilium assembly	--
ENSG00000168237	2.087	1.846	1.826	2.424	1.858	1.561	60	58	36	63	62	34	GLYCTK	glycerate kinase [Source:HGNC Symbol;Acc:HGNC:24247]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00561//Glycerolipid metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00030//Pentose phosphate pathway"	K11529;K11529;K11529;K11529;K11529;K11529	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008887//glycerate kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0061624//fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	--
ENSG00000168243	0.151	0.139	0.027	0.291	0.276	0	5	10	2	8	9	0	GNG4	G protein subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:4407]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541;K04541	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0030308//negative regulation of cell growth	--
ENSG00000168246	13.295	12.617	14.025	11.305	11.459	11.11	824	786	642	519	600	501	UBTD2	ubiquitin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24463]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000168255	11.405	11.492	12.185	14.357	12.292	14.235	338.2	349.05	263.47	318.5	302.3	315.68	POLR2J3	RNA polymerase II subunit J3 [Source:HGNC Symbol;Acc:HGNC:33853]	-	-	-	-	"GO:0005634//nucleus;GO:0005665//RNA polymerase II, core complex"	GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000168256	30.514	32.872	29.903	38.11	35.579	34.778	1323	1506	1037	1262	1356	1109	NKIRAS2	NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0032794//GTPase activating protein binding	GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0032484//Ral protein signal transduction;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043129//surfactant homeostasis;GO:0048286//lung alveolus development	--
ENSG00000168259	26.646	29.274	27.744	26.917	24.314	25.929	961.66	1028.33	720.66	710.19	741.07	662	DNAJC7	DnaJ heat shock protein family (Hsp40) member C7 [Source:HGNC Symbol;Acc:HGNC:12392]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding	GO:0006457//protein folding;GO:0051085//chaperone cofactor-dependent protein refolding;GO:1900034//regulation of cellular response to heat	--
ENSG00000168263	0	0.066	0.03	0	0.026	0.03	0	3	1	0	1	1	KCNV2	potassium voltage-gated channel modifier subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:19698]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000168264	15.765	15.854	15.786	15.085	15.024	15.768	1574	1605	1166	1116	1274	1150	IRF2BP2	interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21729]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003714//transcription corepressor activity;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002327//immature B cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000168267	0	0	0	0	0	0	0	0	0	0	0	0	PTF1A	pancreas associated transcription factor 1a [Source:HGNC Symbol;Acc:HGNC:23734]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009888//tissue development;GO:0010842//retina layer formation;GO:0021549//cerebellum development;GO:0030154//cell differentiation;GO:0030902//hindbrain development;GO:0031016//pancreas development;GO:0031017//exocrine pancreas development;GO:0032502//developmental process;GO:0035881//amacrine cell differentiation;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048663//neuron fate commitment;GO:0048699//generation of neurons;GO:0060042//retina morphogenesis in camera-type eye;GO:0061074//regulation of neural retina development"	bHLH
ENSG00000168268	124.152	125.828	128.274	115.624	111.535	103.926	4590	4721	3564	3130	3456	2831	NT5DC2	5'-nucleotidase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25717]	-	-	-	-	-	GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000168269	0	0	0	0	0	0	0	0	0	0	0	0	FOXI1	forkhead box I1 [Source:HGNC Symbol;Acc:HGNC:3815]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009792//embryo development ending in birth or egg hatching;GO:0030154//cell differentiation;GO:0042472//inner ear morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Fork_head
ENSG00000168273	5.024	6.307	6.579	4.586	5.483	4.585	54	42	40	30	37	32	SMIM4	small integral membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:37257]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000168275	8.247	8.985	10.135	10.875	7.153	8.347	132	137	114	122	90	97	COA6	cytochrome c oxidase assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:18025]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18179	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane;GO:0045277//respiratory chain complex IV	GO:0003723//RNA binding;GO:0005507//copper ion binding;GO:0005515//protein binding	GO:0008535//respiratory chain complex IV assembly;GO:0042774//plasma membrane ATP synthesis coupled electron transport;GO:0042775//mitochondrial ATP synthesis coupled electron transport	--
ENSG00000168280	5.031	4.422	3.783	4.499	5.14	3.978	579	510	313	455	595	363	KIF5C	kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Nervous system;Cancer: specific types	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection;ko04144//Endocytosis;ko04728//Dopaminergic synapse;ko05223//Non-small cell lung cancer	K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0030425//dendrite;GO:0032839//dendrite cytoplasm;GO:0035253//ciliary rootlet;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044295//axonal growth cone;GO:0150034//distal axon;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity	GO:0006996//organelle organization;GO:0007018//microtubule-based movement;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0048489//synaptic vesicle transport;GO:0051028//mRNA transport;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex;GO:0099641//anterograde axonal protein transport	--
ENSG00000168282	15.094	15.696	15.814	14.677	13.187	15.09	840	878	650	605	620	611	MGAT2	"alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7045]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K00736;K00736;K00736	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0008455//alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0009312//oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019082//viral protein processing	--
ENSG00000168283	20.955	18.274	19.628	17.668	18.253	19.871	1418.13	1269.43	927.7	960.94	959.37	1061.6	BMI1	"BMI1 proto-oncogene, polycomb ring finger [Source:HGNC Symbol;Acc:HGNC:1066]"	Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Cancer: overview;Cellular community - eukaryotes	ko05202//Transcriptional misregulation in cancer;ko05206//MicroRNAs in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells	K11459;K11459;K11459	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0071535//RING-like zinc finger domain binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0007379//segment specification;GO:0010468//regulation of gene expression;GO:0030097//hemopoiesis;GO:0036353//histone H2A-K119 monoubiquitination;GO:0045814//negative regulation of gene expression, epigenetic;GO:0048146//positive regulation of fibroblast proliferation;GO:0051443//positive regulation of ubiquitin-protein transferase activity"	--
ENSG00000168286	14.597	15.75	17.12	19.88	18.555	21.051	568	616	492	573	610	596	THAP11	THAP domain containing 11 [Source:HGNC Symbol;Acc:HGNC:23194]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	THAP
ENSG00000168288	33.938	32.882	33.871	36.726	29.079	36.551	984	956	725	786	711	769	MMADHC	metabolism of cobalamin associated D [Source:HGNC Symbol;Acc:HGNC:25221]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding	GO:0009235//cobalamin metabolic process	--
ENSG00000168291	38.94	37.043	41.699	39.417	37.975	44.149	1217	1164	962	912	1003	1004	PDHB	pyruvate dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:8808]	Metabolism;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Signal transduction;Global and overview maps;Endocrine system;Cancer: overview;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K00162;K00162;K00162;K00162;K00162;K00162;K00162;K00162;K00162	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0045254//pyruvate dehydrogenase complex	GO:0003824//catalytic activity;GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0034604//pyruvate dehydrogenase (NAD+) activity	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0006099//tricarboxylic acid cycle;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate	--
ENSG00000168297	9.946	9.78	7.412	8.142	8.937	9.066	507	501	303	321	416	345	PXK	PX domain containing serine/threonine kinase like [Source:HGNC Symbol;Acc:HGNC:23326]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite	GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0035091//phosphatidylinositol binding	GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0032780//negative regulation of ATPase activity;GO:0043271//negative regulation of ion transport;GO:0050804//modulation of chemical synaptic transmission	--
ENSG00000168298	0	0	0	0	0.073	0	0	0	0	0	1	0	H1-4	"H1.4 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4718]"	-	-	-	-	GO:0000786//nucleosome;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006334//nucleosome assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination;GO:0080182//histone H3-K4 trimethylation;GO:0098532//histone H3-K27 trimethylation	--
ENSG00000168300	14.294	12.851	13.978	10.834	10.641	13.737	1146	1020	793	617	695	770	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30483]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;GO:0005515//protein binding	GO:0006464//cellular protein modification process;GO:0006479//protein methylation;GO:0044267//cellular protein metabolic process	--
ENSG00000168301	7.29	6.435	5.401	5.881	7.056	8.604	241	212	132	137	180	197	KCTD6	potassium channel tetramerization domain containing 6 [Source:HGNC Symbol;Acc:HGNC:22235]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031430//M band	GO:0005515//protein binding;GO:0030506//ankyrin binding;GO:0042802//identical protein binding;GO:0097602//cullin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0040008//regulation of growth;GO:0045879//negative regulation of smoothened signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000168303	2.44	2.151	2.277	2.449	1.96	2.624	386	342	266	287	262	302	MPLKIP	M-phase specific PLK1 interacting protein [Source:HGNC Symbol;Acc:HGNC:16002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000168306	11.276	11.996	12.013	8.731	10.516	10.53	512	560	399	293	413	341	ACOX2	acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120]	Metabolism;Cellular Processes;Organismal Systems;Metabolism	Global and overview maps;Transport and catabolism;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko00120//Primary bile acid biosynthesis	K10214;K10214;K10214;K10214	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0003997//acyl-CoA oxidase activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0016401//palmitoyl-CoA oxidase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0033791//3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity;GO:0042803//protein homodimerization activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding"	GO:0000038//very long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0010942//positive regulation of cell death;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088//lipid homeostasis;GO:1902884//positive regulation of response to oxidative stress	--
ENSG00000168309	25.662	26.804	28.026	23.022	23.15	23.859	1473	1521	1200	986	1122	1001	FAM107A	family with sequence similarity 107 member A [Source:HGNC Symbol;Acc:HGNC:30827]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding	GO:0001558//regulation of cell growth;GO:0007049//cell cycle;GO:0030041//actin filament polymerization;GO:0030335//positive regulation of cell migration;GO:0031398//positive regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0031669//cellular response to nutrient levels;GO:0032956//regulation of actin cytoskeleton organization;GO:0040008//regulation of growth;GO:0050890//cognition;GO:0051017//actin filament bundle assembly;GO:0051895//negative regulation of focal adhesion assembly;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071385//cellular response to glucocorticoid stimulus;GO:1900272//negative regulation of long-term synaptic potentiation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000168310	8.707	8.206	11.563	8.84	8.786	9.533	415	384	343	290	347	326	IRF2	interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway"	IRF
ENSG00000168314	0	0	0	0	0	0	0	0	0	0	0	0	MOBP	myelin associated oligodendrocyte basic protein [Source:HGNC Symbol;Acc:HGNC:7189]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0030864//cortical actin cytoskeleton;GO:0043209//myelin sheath;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0019911//structural constituent of myelin sheath	GO:0007399//nervous system development;GO:0032289//central nervous system myelin formation	--
ENSG00000168329	0.016	0.077	0.042	0.313	0.092	0.134	1	5	2	4	5	3	CX3CR1	C-X3-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:2558]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04192;K04192;K04192	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0097447//dendritic tree	GO:0004896//cytokine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0016495//C-X3-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0019960//C-X3-C chemokine binding;GO:0031737//CX3C chemokine receptor binding	"GO:0002052//positive regulation of neuroblast proliferation;GO:0002250//adaptive immune response;GO:0002282//microglial cell activation involved in immune response;GO:0002376//immune system process;GO:0002931//response to ischemia;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007420//brain development;GO:0007613//memory;GO:0009611//response to wounding;GO:0019722//calcium-mediated signaling;GO:0021626//central nervous system maturation;GO:0030336//negative regulation of cell migration;GO:0030595//leukocyte chemotaxis;GO:0032680//regulation of tumor necrosis factor production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0035176//social behavior;GO:0035425//autocrine signaling;GO:0045087//innate immune response;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0048167//regulation of synaptic plasticity;GO:0048874//host-mediated regulation of intestinal microbiota composition;GO:0050767//regulation of neurogenesis;GO:0050769//positive regulation of neurogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050901//leukocyte tethering or rolling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0060074//synapse maturation;GO:0060326//cell chemotaxis;GO:0061760//antifungal innate immune response;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0090026//positive regulation of monocyte chemotaxis;GO:0098883//synapse pruning;GO:0110091//negative regulation of hippocampal neuron apoptotic process;GO:0150090//multiple spine synapse organization, single dendrite;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1904139//regulation of microglial cell migration;GO:1904141//positive regulation of microglial cell migration;GO:1904150//negative regulation of microglial cell mediated cytotoxicity;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000168333	0.038	0.038	0	0	0	0	1	1	0	0	0	0	PPDPFL	pancreatic progenitor cell differentiation and proliferation factor like [Source:HGNC Symbol;Acc:HGNC:31745]	-	-	-	-	-	-	GO:0007275//multicellular organism development;GO:0030154//cell differentiation	--
ENSG00000168334	0.015	0.076	0.025	0	0.022	0.021	2	5	1	0	1	2	XIRP1	xin actin binding repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:14301]	-	-	-	-	GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0032091//negative regulation of protein binding	--
ENSG00000168348	0	0	0	0	0	0	0	0	0	0	0	0	INSM2	INSM transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:17539]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010564//regulation of cell cycle process;GO:0030182//neuron differentiation	zf-C2H2
ENSG00000168350	0.253	0.252	0.222	0.154	0.254	0.139	20.09	20.11	13.05	9.06	17.06	8.02	DEGS2	"delta 4-desaturase, sphingolipid 2 [Source:HGNC Symbol;Acc:HGNC:20113]"	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04712;K04712;K04712	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000170//sphingosine hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0042284//sphingolipid delta-4 desaturase activity	GO:0006629//lipid metabolic process;GO:0006667//sphinganine metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000168356	0.029	0.019	0.096	0.013	0.05	0.013	3	2	10	1	6	1	SCN11A	sodium voltage-gated channel alpha subunit 11 [Source:HGNC Symbol;Acc:HGNC:10583]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0044299//C-fiber;GO:0070062//extracellular exosome	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0009410//response to xenobiotic stimulus;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051930//regulation of sensory perception of pain;GO:0055085//transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000168374	127.074	129.788	123.834	126.49	115.004	129.127	4199	4315	3029	3098	3211	3111	ARF4	ADP ribosylation factor 4 [Source:HGNC Symbol;Acc:HGNC:655]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07939	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032587//ruffle membrane;GO:0043197//dendritic spine;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0006471//protein ADP-ribosylation;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007612//learning;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016477//cell migration;GO:0031584//activation of phospholipase D activity;GO:0043066//negative regulation of apoptotic process;GO:0045176//apical protein localization;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050807//regulation of synapse organization;GO:0060271//cilium assembly;GO:0060996//dendritic spine development;GO:0061512//protein localization to cilium;GO:0099175//regulation of postsynapse organization;GO:2000377//regulation of reactive oxygen species metabolic process"	--
ENSG00000168385	152.538	136.572	133.741	123.506	128.8	124.739	9423	8584	6227	5680	6466	5731	SEPTIN2	septin 2 [Source:HGNC Symbol;Acc:HGNC:7729]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16942;K16942	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0005938//cell cortex;GO:0005940//septin ring;GO:0008021//synaptic vesicle;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030496//midbody;GO:0031105//septin complex;GO:0031514//motile cilium;GO:0032153//cell division site;GO:0032154//cleavage furrow;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection;GO:0045171//intercellular bridge;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome;GO:0097227//sperm annulus;GO:0097730//non-motile cilium"	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0017157//regulation of exocytosis;GO:0030154//cell differentiation;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0060271//cilium assembly;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000168386	11.786	9.971	6.277	4.654	6.711	8.191	773	675	317	232	368	410	FILIP1L	filamin A interacting protein 1 like [Source:HGNC Symbol;Acc:HGNC:24589]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000168389	6.275	6.335	5.795	5.823	5.039	6.007	260	264	189	171	188	193	MFSD2A	major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0015245//fatty acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0051978//lysophospholipid:sodium symporter activity;GO:0140348//lysophosphatidylcholine flippase activity;GO:1901480//oleate transmembrane transporter activity	GO:0003406//retinal pigment epithelium development;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006869//lipid transport;GO:0007420//brain development;GO:0008594//photoreceptor cell morphogenesis;GO:0008643//carbohydrate transport;GO:0009267//cellular response to starvation;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0015711//organic anion transport;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0021766//hippocampus development;GO:0030307//positive regulation of cell growth;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0034379//very-low-density lipoprotein particle assembly;GO:0035633//maintenance of blood-brain barrier;GO:0035845//photoreceptor cell outer segment organization;GO:0040014//regulation of multicellular organism growth;GO:0045056//transcytosis;GO:0050773//regulation of dendrite development;GO:0050890//cognition;GO:0051977//lysophospholipid transport;GO:0055085//transmembrane transport;GO:0060042//retina morphogenesis in camera-type eye;GO:0060856//establishment of blood-brain barrier;GO:0061744//motor behavior;GO:0071702//organic substance transport;GO:0097009//energy homeostasis;GO:0140329//lysophospholipid translocation;GO:0150011//regulation of neuron projection arborization;GO:0150104//transport across blood-brain barrier;GO:0150172//regulation of phosphatidylcholine metabolic process;GO:0150175//regulation of phosphatidylethanolamine metabolic process;GO:0150178//regulation of phosphatidylserine metabolic process;GO:1990379//lipid transport across blood-brain barrier	--
ENSG00000168393	10.277	10.642	12.737	11.669	10.889	10.247	225	234	206	189	201	163	DTYMK	deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K00943;K00943	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0004798//thymidylate kinase activity;GO:0005524//ATP binding;GO:0009041//uridylate kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006227//dUDP biosynthetic process;GO:0006233//dTDP biosynthetic process;GO:0006235//dTTP biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0046105//thymidine biosynthetic process;GO:0046940//nucleoside monophosphate phosphorylation;GO:0071363//cellular response to growth factor stimulus	--
ENSG00000168394	13.494	14.783	17.163	23.693	21.354	23.221	734	807	700	942	984	931	TAP1	"transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Immune disease;Immune system;Membrane transport	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation;ko02010//ABC transporters	K05653;K05653;K05653;K05653;K05653;K05653;K05653;K05653	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030670//phagocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0034451//centriolar satellite;GO:0042824//MHC class I peptide loading complex;GO:0042825//TAP complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015433//ABC-type peptide antigen transporter activity;GO:0015440//ABC-type peptide transporter activity;GO:0023029//MHC class Ib protein binding;GO:0042287//MHC protein binding;GO:0042288//MHC class I protein binding;GO:0042605//peptide antigen binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0046978//TAP1 binding;GO:0046979//TAP2 binding;GO:0140359//ABC-type transporter activity;GO:1904680//peptide transmembrane transporter activity	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006952//defense response;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0046967//cytosol to endoplasmic reticulum transport;GO:0055085//transmembrane transport"	--
ENSG00000168395	5.687	4.609	5.845	6.753	5.702	5.226	410	379	358	386	369	321	ING5	inhibitor of growth family member 5 [Source:HGNC Symbol;Acc:HGNC:19421]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070776//MOZ/MORF histone acetyltransferase complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0006260//DNA replication;GO:0006275//regulation of DNA replication;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006473//protein acetylation;GO:0008285//negative regulation of cell population proliferation;GO:0016570//histone modification;GO:0016573//histone acetylation;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045926//negative regulation of growth;GO:0050793//regulation of developmental process;GO:0051726//regulation of cell cycle;GO:1903706//regulation of hemopoiesis;GO:2000278//regulation of DNA biosynthetic process;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000168397	13.06	15.101	16.94	14.699	16.762	15.455	592	641	515	479	605	534	ATG4B	autophagy related 4B cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:20790]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K08342;K08342	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019786//Atg8-specific protease activity;GO:0097110//scaffold protein binding	GO:0000423//mitophagy;GO:0006508//proteolysis;GO:0006914//autophagy;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0016237//lysosomal microautophagy;GO:0031173//otolith mineralization completed early in development;GO:0034497//protein localization to phagophore assembly site;GO:0051697//protein delipidation	--
ENSG00000168398	0.369	0.247	0.153	0.244	0.402	0.332	33	24	16	15	30	20	BDKRB2	bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: parasitic;Sensory system;Immune system;Excretory system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04022//cGMP-PKG signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko04750//Inflammatory mediator regulation of TRP channels;ko04610//Complement and coagulation cascades;ko04961//Endocrine and other factor-regulated calcium reabsorption	K03916;K03916;K03916;K03916;K03916;K03916;K03916;K03916;K03916;K03916	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0002020//protease binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004947//bradykinin receptor activity;GO:0005515//protein binding;GO:0031702//type 1 angiotensin receptor binding;GO:0046982//protein heterodimerization activity	GO:0006939//smooth muscle contraction;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008015//blood circulation;GO:0009651//response to salt stress;GO:0019229//regulation of vasoconstriction;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0042310//vasoconstriction;GO:0042311//vasodilation;GO:0043114//regulation of vascular permeability;GO:0050482//arachidonic acid secretion;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:1902239//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	--
ENSG00000168404	0.136	0.183	0.053	0.037	0.128	0.458	7	6	2	1	4	8	MLKL	mixed lineage kinase domain like pseudokinase [Source:HGNC Symbol;Acc:HGNC:26617]	Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Cell growth and death;Signal transduction	ko05132//Salmonella infection;ko04217//Necroptosis;ko04668//TNF signaling pathway	K08849;K08849;K08849	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death;GO:0051607//defense response to virus;GO:0070207//protein homotrimerization;GO:0070266//necroptotic process;GO:0097527//necroptotic signaling pathway;GO:0097528//execution phase of necroptosis	--
ENSG00000168411	4.562	4.329	4.517	4.23	3.639	3.595	434	408	324	309	309	256	RFWD3	ring finger and WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:25539]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0035861//site of double-strand break;GO:0090734//site of DNA damage	GO:0002039//p53 binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0097371//MDM2/MDM4 family protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0016567//protein ubiquitination;GO:0031052//chromosome breakage;GO:0031297//replication fork processing;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0036297//interstrand cross-link repair;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000168412	0	0	0	0	0	0	0	0	0	0	0	0	MTNR1A	melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Environmental adaptation	ko04080//Neuroactive ligand-receptor interaction;ko04713//Circadian entrainment	K04285;K04285	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008502//melatonin receptor activity;GO:0042562//hormone binding;GO:0097159//organic cyclic compound binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007617//mating behavior;GO:0007623//circadian rhythm"	--
ENSG00000168418	0	0	0	0	0	0	0	0	0	0	0	0	KCNG4	potassium voltage-gated channel modifier subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:19697]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0044325//transmembrane transporter binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000168421	0	0	0	0	0	0	0	0	0	0	0	0	RHOH	ras homolog family member H [Source:HGNC Symbol;Acc:HGNC:686]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05132//Salmonella infection;ko04670//Leukocyte transendothelial migration	K07873;K07873	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019210//kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008045//motor neuron axon guidance;GO:0008360//regulation of cell shape;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030217//T cell differentiation;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043086//negative regulation of catalytic activity;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043652//engulfment of apoptotic cell;GO:0045576//mast cell activation;GO:0045582//positive regulation of T cell differentiation;GO:1902622//regulation of neutrophil migration"	--
ENSG00000168427	2.334	3.502	2.711	2.135	2.174	1.841	183	276	157	124	144	105	KLHL30	kelch like family member 30 [Source:HGNC Symbol;Acc:HGNC:24770]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000168434	9.096	8.923	10.046	7.576	9.138	9.595	549	546	433	334	470	425	COG7	component of oligomeric golgi complex 7 [Source:HGNC Symbol;Acc:HGNC:18622]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006486//protein glycosylation;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0033365//protein localization to organelle;GO:0034067//protein localization to Golgi apparatus;GO:0050821//protein stabilization;GO:0070085//glycosylation"	--
ENSG00000168438	5.762	5.934	5.463	4.422	4.978	5.373	463	477	314	264	315	305	CDC40	cell division cycle 40 [Source:HGNC Symbol;Acc:HGNC:17350]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12816	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:1990403//embryonic brain development"	--
ENSG00000168439	79.529	80.287	84.103	79.526	74.535	78.862	3459	3545	2720	2594	2745	2515	STIP1	stress induced phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11387]	Human Diseases	Neurodegenerative disease	ko05020//Prion disease	K09553	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0101031//chaperone complex;GO:0120293//dynein axonemal particle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0051879//Hsp90 protein binding	GO:0006457//protein folding;GO:0098761//cellular response to interleukin-7	--
ENSG00000168447	0.978	0.597	0.102	0.107	0.13	0.233	40	29	4	3	5	9	SCNN1B	sodium channel epithelial 1 subunit beta [Source:HGNC Symbol;Acc:HGNC:10600]	Organismal Systems;Organismal Systems	Sensory system;Excretory system	ko04742//Taste transduction;ko04960//Aldosterone-regulated sodium reabsorption	K04825;K04825	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034706//sodium channel complex;GO:0070062//extracellular exosome	GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0050699//WW domain binding	GO:0002269//leukocyte activation involved in inflammatory response;GO:0002283//neutrophil activation involved in immune response;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0008217//regulation of blood pressure;GO:0009410//response to xenobiotic stimulus;GO:0010467//gene expression;GO:0014824//artery smooth muscle contraction;GO:0032094//response to food;GO:0032341//aldosterone metabolic process;GO:0034101//erythrocyte homeostasis;GO:0034220//ion transmembrane transport;GO:0035264//multicellular organism growth;GO:0035725//sodium ion transmembrane transport;GO:0036254//cellular response to amiloride;GO:0042045//epithelial fluid transport;GO:0050891//multicellular organismal water homeostasis;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050914//sensory perception of salty taste;GO:0050915//sensory perception of sour taste;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0070254//mucus secretion;GO:0070944//neutrophil-mediated killing of bacterium;GO:0071468//cellular response to acidic pH;GO:0097274//urea homeostasis;GO:0098719//sodium ion import across plasma membrane;GO:1904045//cellular response to aldosterone;GO:1904117//cellular response to vasopressin	--
ENSG00000168453	1.053	1.164	1.197	1.752	0.867	1.07	93	74	68	112	82	87	HR	HR lysine demethylase and nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:5172]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0140683//histone H3-di/monomethyl-lysine-9 demethylase activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0033169//histone H3-K9 demethylation	--
ENSG00000168454	0	0	0	0	0	0	0	0	0	0	0	0	TXNDC2	thioredoxin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16470]	-	-	-	-	GO:0005737//cytoplasm	GO:0004791//thioredoxin-disulfide reductase activity;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045454//cell redox homeostasis;GO:0098869//cellular oxidant detoxification	--
ENSG00000168461	10.758	11.057	9.207	9.747	9.101	8.876	845	856	526	566	625	503	RAB31	"RAB31, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9771]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07891	GO:0001891//phagocytic cup;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0036186//early phagosome membrane;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	"GO:0006886//intracellular protein transport;GO:0031623//receptor internalization;GO:0032869//cellular response to insulin stimulus;GO:0043001//Golgi to plasma membrane protein transport;GO:0045055//regulated exocytosis;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0090382//phagosome maturation"	--
ENSG00000168476	6.114	9.118	10.341	7.461	9.366	7.93	167	213	160	153	208	150	REEP4	receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0006998//nuclear envelope organization;GO:0007049//cell cycle;GO:0007084//mitotic nuclear membrane reassembly;GO:0051301//cell division;GO:0071786//endoplasmic reticulum tubular network organization	--
ENSG00000168477	0.483	0.586	0.526	0.529	0.5	0.325	83	81	84	71	93	58	TNXB	tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Cancer: overview;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04512//ECM-receptor interaction	K06252;K06252;K06252;K06252;K06252	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0090733//tenascin complex	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0098633//collagen fibril binding	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006641//triglyceride metabolic process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0008284//positive regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030155//regulation of cell adhesion;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030334//regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032963//collagen metabolic process;GO:0043506//regulation of JUN kinase activity;GO:0045595//regulation of cell differentiation;GO:0048251//elastic fiber assembly;GO:0098609//cell-cell adhesion;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:1901390//positive regulation of transforming growth factor beta activation;GO:1904028//positive regulation of collagen fibril organization;GO:1905935//positive regulation of cell fate determination	--
ENSG00000168481	0.015	0.061	0.063	0.063	0.106	0.1	1	1	3	3	6	1	LGI3	leucine rich repeat LGI family member 3 [Source:HGNC Symbol;Acc:HGNC:18711]	-	-	-	-	GO:0005576//extracellular region;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0003824//catalytic activity;GO:0005515//protein binding	GO:0006887//exocytosis;GO:0017157//regulation of exocytosis	--
ENSG00000168484	0	0	0	0	0	0	0	0	0	0	0	0	SFTPC	surfactant protein C [Source:HGNC Symbol;Acc:HGNC:10802]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042599//lamellar body;GO:0045334//clathrin-coated endocytic vesicle;GO:0097208//alveolar lamellar body;GO:0097486//multivesicular body lumen	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007585//respiratory gaseous exchange by respiratory system	--
ENSG00000168487	19.764	23.071	17.452	16.038	16.977	15.034	824	927	549	517	585	442	BMP1	bone morphogenetic protein 1 [Source:HGNC Symbol;Acc:HGNC:1067]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0031982//vesicle	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005125//cytokine activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001502//cartilage condensation;GO:0001503//ossification;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0051216//cartilage development;GO:0061036//positive regulation of cartilage development	--
ENSG00000168488	23.467	24.526	27.345	29.058	27.975	35.315	1667	1841	1464	1486	1725	1819	ATXN2L	ataxin 2 like [Source:HGNC Symbol;Acc:HGNC:31326]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05017//Spinocerebellar ataxia	K23625;K23625;K23625	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0016071//mRNA metabolic process;GO:0034063//stress granule assembly	--
ENSG00000168490	0.356	0.396	0.307	0.23	1.368	0.356	22	20	14	9	40	16	PHYHIP	phytanoyl-CoA 2-hydroxylase interacting protein [Source:HGNC Symbol;Acc:HGNC:16865]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:1990782//protein tyrosine kinase binding	GO:0008104//protein localization	--
ENSG00000168491	1.343	1.551	0.575	0.239	1.127	1.085	39	52	20	10	32	13	CCDC110	coiled-coil domain containing 110 [Source:HGNC Symbol;Acc:HGNC:28504]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000168495	7.706	9.109	10.853	11.226	8.964	12.003	655	659	492	480	536	453	POLR3D	RNA polymerase III subunit D [Source:HGNC Symbol;Acc:HGNC:1080]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03026;K03026	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity	GO:0002376//immune system process;GO:0006383//transcription by RNA polymerase III;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus	--
ENSG00000168496	8.661	6.828	9.196	7.232	6.51	6.21	355	287	284	224	230	186	FEN1	flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03030//DNA replication;ko03410//Base excision repair;ko03450//Non-homologous end-joining	K04799;K04799;K04799	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0032991//protein-containing complex"	"GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008309//double-stranded DNA exodeoxyribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0017108//5'-flap endonuclease activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0048256//flap endonuclease activity"	"GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006287//base-excision repair, gap-filling;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007613//memory;GO:0009650//UV protection;GO:0032201//telomere maintenance via semi-conservative replication;GO:0043137//DNA replication, removal of RNA primer;GO:0045876//positive regulation of sister chromatid cohesion;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000168497	0.458	0.377	0.128	0.511	0.897	0.412	29	24	6	24	48	19	CAVIN2	caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0045121//membrane raft	GO:0001786//phosphatidylserine binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding	GO:0097320//plasma membrane tubulation	--
ENSG00000168502	5.973	5.549	3.526	2.23	3.744	2.458	852	796	371	232	441	258	MTCL1	microtubule crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:29121]	-	-	-	-	GO:0000922//spindle pole;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030496//midbody;GO:0097427//microtubule bundle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity	GO:0001578//microtubule bundle formation;GO:0010506//regulation of autophagy;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000168505	0.037	0.073	0	0	0.087	0.051	1	2	0	0	2	1	GBX2	gastrulation brain homeobox 2 [Source:HGNC Symbol;Acc:HGNC:4186]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001569//branching involved in blood vessel morphogenesis;GO:0001755//neural crest cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0021549//cerebellum development;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0021568//rhombomere 2 development;GO:0021794//thalamus development;GO:0021884//forebrain neuron development;GO:0021930//cerebellar granule cell precursor proliferation;GO:0030902//hindbrain development;GO:0030917//midbrain-hindbrain boundary development;GO:0035239//tube morphogenesis;GO:0042472//inner ear morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048483//autonomic nervous system development;GO:0051960//regulation of nervous system development"	Homeobox
ENSG00000168509	0.038	0	0	0	0	0	1	0	0	0	0	0	HJV	hemojuvelin BMP co-receptor [Source:HGNC Symbol;Acc:HGNC:4887]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K23100	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0070724//BMP receptor complex;GO:0098797//plasma membrane protein complex;GO:0110165//cellular anatomical entity;GO:1990712//HFE-transferrin receptor complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0036122//BMP binding;GO:0098821//BMP receptor activity;GO:1990459//transferrin receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006879//cellular iron ion homeostasis;GO:0016540//protein autoprocessing;GO:0030509//BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055072//iron ion homeostasis;GO:0071773//cellular response to BMP stimulus	--
ENSG00000168515	0	0	0	0	0	0	0	0	0	0	0	0	SCGB1D1	secretoglobin family 1D member 1 [Source:HGNC Symbol;Acc:HGNC:18395]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	-	--
ENSG00000168517	7.454	6.451	7.674	7.964	8.665	8.821	200	179	154	158	203	173	HEXIM2	HEXIM P-TEFb complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28591]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0042802//identical protein binding;GO:0097322//7SK snRNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000168522	19.707	18.263	16.846	14.404	14.974	14.478	807	725	502	433	530	421.71	FNTA	"farnesyltransferase, CAAX box, alpha [Source:HGNC Symbol;Acc:HGNC:3782]"	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K05955	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005953//CAAX-protein geranylgeranyltransferase complex;GO:0005965//protein farnesyltransferase complex	GO:0004659//prenyltransferase activity;GO:0004660//protein farnesyltransferase activity;GO:0004661//protein geranylgeranyltransferase activity;GO:0004662//CAAX-protein geranylgeranyltransferase activity;GO:0004663//Rab geranylgeranyltransferase activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0030548//acetylcholine receptor regulator activity;GO:0030971//receptor tyrosine kinase binding;GO:0043014//alpha-tubulin binding	GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007528//neuromuscular junction development;GO:0018342//protein prenylation;GO:0018343//protein farnesylation;GO:0018344//protein geranylgeranylation;GO:0045213//neurotransmitter receptor metabolic process;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0090044//positive regulation of tubulin deacetylation;GO:0090045//positive regulation of deacetylase activity	--
ENSG00000168528	11.368	11.941	11.131	15.86	14.567	10.113	448	473	324	463	485	290	SERINC2	serine incorporator 2 [Source:HGNC Symbol;Acc:HGNC:23231]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	-	GO:0006658//phosphatidylserine metabolic process;GO:0006665//sphingolipid metabolic process	--
ENSG00000168530	0.111	0.055	0.15	0.224	0.656	0.305	2	1	2	3	10	4	MYL1	myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582]	-	-	-	-	GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0043292//contractile fiber	GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle	GO:0006936//muscle contraction;GO:0030049//muscle filament sliding	--
ENSG00000168538	8.975	7.668	5.932	6.288	7.186	7.009	842	689	411	414	517	440	TRAPPC11	trafficking protein particle complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:25751]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0016192//vesicle-mediated transport;GO:0045054//constitutive secretory pathway;GO:0048208//COPII vesicle coating;GO:0061635//regulation of protein complex stability;GO:0099022//vesicle tethering	--
ENSG00000168539	1.439	1.391	1.011	1.894	2.093	2.041	79	76	41	77	96	56	CHRM1	cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems	Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Signal transduction;Cell motility;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04725//Cholinergic synapse	K04129;K04129;K04129;K04129;K04129;K04129;K04129;K04129	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032279//asymmetric synapse;GO:0043679//axon terminus;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0098981//cholinergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0099529//neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007207//phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0007399//nervous system development;GO:0040012//regulation of locomotion;GO:0043270//positive regulation of ion transport;GO:0046541//saliva secretion;GO:0050890//cognition;GO:0060078//regulation of postsynaptic membrane potential;GO:0060251//regulation of glial cell proliferation;GO:0090316//positive regulation of intracellular protein transport;GO:0095500//acetylcholine receptor signaling pathway;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000168542	182.726	195.716	79.236	60.332	78.248	76.536	20357	22401	6664	5089	7528	6215	COL3A1	collagen type III alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2201]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Cardiovascular disease;Infectious disease: parasitic;Endocrine system;Immune system;Digestive system;Endocrine and metabolic disease	ko05415//Diabetic cardiomyopathy;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications	K19720;K19720;K19720;K19720;K19720;K19720	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005586//collagen type III trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0002020//protease binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048407//platelet-derived growth factor binding	GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001894//tissue homeostasis;GO:0002062//chondrocyte differentiation;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007507//heart development;GO:0009314//response to radiation;GO:0010467//gene expression;GO:0018149//peptide cross-linking;GO:0021987//cerebral cortex development;GO:0030168//platelet activation;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030324//lung development;GO:0032905//transforming growth factor beta1 production;GO:0034097//response to cytokine;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035264//multicellular organism growth;GO:0035904//aorta development;GO:0036022//limb joint morphogenesis;GO:0042060//wound healing;GO:0043588//skin development;GO:0048144//fibroblast proliferation;GO:0048251//elastic fiber assembly;GO:0048565//digestive tract development;GO:0050777//negative regulation of immune response;GO:0051216//cartilage development;GO:0060350//endochondral bone morphogenesis;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0097435//supramolecular fiber organization;GO:1990776//response to angiotensin;GO:2001223//negative regulation of neuron migration	--
ENSG00000168546	12.683	14.207	9.04	4.432	6.577	3	459	514	294	145	246	115	GFRA2	GDNF family receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4244]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0043235//receptor complex	GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0038023//signaling receptor activity	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway	--
ENSG00000168556	5.621	5.654	3.737	3.434	5.61	4.43	166	188	92	100	153	110	ING2	inhibitor of growth family member 2 [Source:HGNC Symbol;Acc:HGNC:6063]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016580//Sin3 complex;GO:0016602//CCAAT-binding factor complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0035091//phosphatidylinositol binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007141//male meiosis I;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008285//negative regulation of cell population proliferation;GO:0030317//flagellated sperm motility;GO:0030336//negative regulation of cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031065//positive regulation of histone deacetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048133//male germ-line stem cell asymmetric division;GO:0072520//seminiferous tubule development;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:2000772//regulation of cellular senescence;GO:2001020//regulation of response to DNA damage stimulus;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000168564	5.273	5.489	5.525	4.021	2.983	4.377	291	321	240	183	150	199	CDKN2AIP	CDKN2A interacting protein [Source:HGNC Symbol;Acc:HGNC:24325]	-	-	-	-	GO:0001652//granular component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0002039//p53 binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0009967//positive regulation of signal transduction;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0031647//regulation of protein stability	--
ENSG00000168566	2.269	1.344	1.533	1.874	1.695	1.984	167	117	98	102	124	125	SNRNP48	small nuclear ribonucleoprotein U11/U12 subunit 48 [Source:HGNC Symbol;Acc:HGNC:21368]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000168569	8.076	9.571	8.474	8.411	8.347	10.794	201.83	246.71	152.36	156.44	175.55	194.8	TMEM223	transmembrane protein 223 [Source:HGNC Symbol;Acc:HGNC:28464]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007399//nervous system development	--
ENSG00000168575	30.115	27.585	31.444	37.405	38.682	44.188	2109	1992	1701	2038	2355	2174	SLC20A2	solute carrier family 20 member 2 [Source:HGNC Symbol;Acc:HGNC:10947]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001618//virus receptor activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0005436//sodium:phosphate symporter activity;GO:0015293//symporter activity;GO:0038023//signaling receptor activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0035435//phosphate ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0046718//viral entry into host cell;GO:0055085//transmembrane transport	--
ENSG00000168582	0	0	0	0	0	0	0	0	0	0	0	0	CRYGA	crystallin gamma A [Source:HGNC Symbol;Acc:HGNC:2408]	-	-	-	-	GO:0005575//cellular_component	GO:0005212//structural constituent of eye lens	GO:0001654//eye development;GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000168589	0.744	1.039	1.704	0.622	0.548	0.317	11	13	15	6	7	3	DYNLRB2	dynein light chain roadblock-type 2 [Source:HGNC Symbol;Acc:HGNC:15467]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K10419	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0097542//ciliary tip;GO:0110165//cellular anatomical entity	GO:0003777//microtubule motor activity;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000168591	17.185	16.354	18.233	21.385	19.955	20.436	737	713	592	692	716	643	TMUB2	transmembrane and ubiquitin like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28459]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000168594	0	0	0	0	0	0	0	0	0	0	0	0	ADAM29	ADAM metallopeptidase domain 29 [Source:HGNC Symbol;Acc:HGNC:207]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990913//sperm head plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0008584//male gonad development	--
ENSG00000168610	69.052	70.397	72.296	50.71	56.662	61.904	5584	5694	4315	3012	3811	3613	STAT3	signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Cancer: overview;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cellular community - eukaryotes;Signal transduction;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Endocrine system;Immune disease	"ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04068//FoxO signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko04917//Prolactin signaling pathway;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko04920//Adipocytokine signaling pathway;ko05321//Inflammatory bowel disease"	K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692;K04692	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0031490//chromatin DNA binding;GO:0035591//signaling adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070878//primary miRNA binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001659//temperature homeostasis;GO:0001754//eye photoreceptor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007399//nervous system development;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010507//negative regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0019827//stem cell population maintenance;GO:0019953//sexual reproduction;GO:0030335//positive regulation of cell migration;GO:0030522//intracellular receptor signaling pathway;GO:0032355//response to estradiol;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032870//cellular response to hormone stimulus;GO:0033210//leptin-mediated signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0042755//eating behavior;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043434//response to peptide hormone;GO:0044320//cellular response to leptin stimulus;GO:0044321//response to leptin;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0045820//negative regulation of glycolytic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048708//astrocyte differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051726//regulation of cell cycle;GO:0060019//radial glial cell differentiation;GO:0060259//regulation of feeding behavior;GO:0060396//growth hormone receptor signaling pathway;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0070102//interleukin-6-mediated signaling pathway;GO:0071310//cellular response to organic substance;GO:0072538//T-helper 17 type immune response;GO:0072540//T-helper 17 cell lineage commitment;GO:0097009//energy homeostasis;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904685//positive regulation of metalloendopeptidase activity;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:1905618//positive regulation of miRNA mediated inhibition of translation;GO:2000635//negative regulation of primary miRNA processing;GO:2000637//positive regulation of gene silencing by miRNA;GO:2000737//negative regulation of stem cell differentiation;GO:2001223//negative regulation of neuron migration"	STAT
ENSG00000168612	3.569	3.863	3.772	4.772	3.668	3.877	205	223	160	203	178	162	ZSWIM1	zinc finger SWIM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:16155]	-	-	-	-	GO:0005634//nucleus	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000168615	86.094	72.355	74.431	66.977	66.943	81.591	7344	6209	4726	4240	4851	5092	ADAM9	ADAM metallopeptidase domain 9 [Source:HGNC Symbol;Acc:HGNC:216]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031233//intrinsic component of external side of plasma membrane;GO:0070062//extracellular exosome	GO:0004222//metalloendopeptidase activity;GO:0005080//protein kinase C binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0043236//laminin binding;GO:0046872//metal ion binding;GO:1902945//metalloendopeptidase activity involved in amyloid precursor protein catabolic process	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0010042//response to manganese ion;GO:0016477//cell migration;GO:0016485//protein processing;GO:0030216//keratinocyte differentiation;GO:0030335//positive regulation of cell migration;GO:0031293//membrane protein intracellular domain proteolysis;GO:0033627//cell adhesion mediated by integrin;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0033631//cell-cell adhesion mediated by integrin;GO:0034241//positive regulation of macrophage fusion;GO:0034612//response to tumor necrosis factor;GO:0042117//monocyte activation;GO:0042542//response to hydrogen peroxide;GO:0042987//amyloid precursor protein catabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0050714//positive regulation of protein secretion;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051384//response to glucocorticoid;GO:0051549//positive regulation of keratinocyte migration;GO:0051592//response to calcium ion;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000168619	0	0	0	0	0	0	0	0	0	0	0	0	ADAM18	ADAM metallopeptidase domain 18 [Source:HGNC Symbol;Acc:HGNC:196]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007283//spermatogenesis;GO:0007339//binding of sperm to zona pellucida;GO:0030154//cell differentiation	--
ENSG00000168621	0	0.106	0	0	0	0	0	3	0	0	0	0	GDNF	glial cell derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:4232]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K05452	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030116//glial cell-derived neurotrophic factor receptor binding;GO:0030971//receptor tyrosine kinase binding;GO:0042803//protein homodimerization activity;GO:1902379//chemoattractant activity involved in axon guidance	GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001755//neural crest cell migration;GO:0001759//organ induction;GO:0001941//postsynaptic membrane organization;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008344//adult locomotory behavior;GO:0010468//regulation of gene expression;GO:0021516//dorsal spinal cord development;GO:0021784//postganglionic parasympathetic fiber development;GO:0030432//peristalsis;GO:0031175//neuron projection development;GO:0032770//positive regulation of monooxygenase activity;GO:0033603//positive regulation of dopamine secretion;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048255//mRNA stabilization;GO:0048484//enteric nervous system development;GO:0048485//sympathetic nervous system development;GO:0048568//embryonic organ development;GO:0048731//system development;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0060676//ureteric bud formation;GO:0060688//regulation of morphogenesis of a branching structure;GO:0061642//chemoattraction of axon;GO:0071679//commissural neuron axon guidance;GO:0072107//positive regulation of ureteric bud formation;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:2000736//regulation of stem cell differentiation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001260//regulation of semaphorin-plexin signaling pathway	--
ENSG00000168631	0	0	0	0	0	0	0	0	0	0	0	0	MUCL3	mucin like 3 [Source:HGNC Symbol;Acc:HGNC:21666]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000168634	0	0	0	0	0	0	0	0	0	0	0	0	WFDC13	WAP four-disulfide core domain 13 [Source:HGNC Symbol;Acc:HGNC:16131]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000168646	11.921	13.316	12.878	15.39	14.536	14.4	786	809	639	756	750	710	AXIN2	axin 2 [Source:HGNC Symbol;Acc:HGNC:904]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05210//Colorectal cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer	K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385;K04385	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0070411//I-SMAD binding	GO:0001756//somitogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001957//intramembranous ossification;GO:0003139//secondary heart field specification;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0008219//cell death;GO:0008283//cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010942//positive regulation of cell death;GO:0016055//Wnt signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0030282//bone mineralization;GO:0032423//regulation of mismatch repair;GO:0034613//cellular protein localization;GO:0042476//odontogenesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043570//maintenance of DNA repeat elements;GO:0045668//negative regulation of osteoblast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0048255//mRNA stabilization;GO:0061181//regulation of chondrocyte development;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0071407//cellular response to organic cyclic compound;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000054//negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	--
ENSG00000168653	91.048	91.305	100.096	111.095	79.984	85.692	1027	1035	834	928	762	703	NDUFS5	NADH:ubiquinone oxidoreductase subunit S5 [Source:HGNC Symbol;Acc:HGNC:7712]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938;K03938	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000168658	0.105	0.114	0.139	0.042	0	0	5	11	7	1	0	0	VWA3B	von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	-	-	--
ENSG00000168661	1.899	1.499	1.669	1.17	2.31	1.914	102	82	67	44	76	58	ZNF30	zinc finger protein 30 [Source:HGNC Symbol;Acc:HGNC:13090]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000168671	3.836	5.748	4.724	4.093	4.435	1.924	151	208	142	124	141	68	UGT3A2	UDP glycosyltransferase family 3 member A2 [Source:HGNC Symbol;Acc:HGNC:27266]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0071412//cellular response to genistein	--
ENSG00000168672	103.261	99.93	107.131	104.222	109.204	112.955	11588	11163	8863	8707	10313	9240	LRATD2	LRAT domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24166]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding	-	--
ENSG00000168675	2.691	4.276	1.765	1.543	2.425	1.242	357	427	194	135	193	127	LDLRAD4	low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0070412//R-SMAD binding	GO:0009968//negative regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation	--
ENSG00000168676	0.137	0.016	0.022	0.066	0	0	2	1	1	3	0	0	KCTD19	potassium channel tetramerization domain containing 19 [Source:HGNC Symbol;Acc:HGNC:24753]	-	-	-	-	-	GO:0005515//protein binding	GO:0051260//protein homooligomerization	--
ENSG00000168679	41.289	41.804	44.696	39.134	41.041	39.369	1897	1863	1462	1275	1538	1265	SLC16A4	solute carrier family 16 member 4 [Source:HGNC Symbol;Acc:HGNC:10925]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport	--
ENSG00000168685	0.032	0.031	0	0	0	0	3	3	0	0	0	0	IL7R	interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction;Signal transduction;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04068//FoxO signaling pathway;ko05340//Primary immunodeficiency	K05072;K05072;K05072;K05072;K05072;K05072;K05072	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0003823//antigen binding;GO:0004896//cytokine receptor activity;GO:0004917//interleukin-7 receptor activity;GO:0005515//protein binding	GO:0000018//regulation of DNA recombination;GO:0000902//cell morphogenesis;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008361//regulation of cell size;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0030097//hemopoiesis;GO:0030217//T cell differentiation;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0038111//interleukin-7-mediated signaling pathway;GO:0042100//B cell proliferation;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048535//lymph node development;GO:0048872//homeostasis of number of cells;GO:0050830//defense response to Gram-positive bacterium;GO:0070233//negative regulation of T cell apoptotic process;GO:1904894//positive regulation of receptor signaling pathway via STAT	--
ENSG00000168701	35.708	40.546	41.889	45.145	43.783	43.039	576	657	500	540	597	505	TMEM208	transmembrane protein 208 [Source:HGNC Symbol;Acc:HGNC:25015]	-	-	-	-	GO:0005773//vacuole;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006624//vacuolar protein processing;GO:0006914//autophagy	--
ENSG00000168702	0.732	0.553	0.465	0.328	0.438	0.495	225	162	113	69	71	74	LRP1B	LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport	--
ENSG00000168703	0	0	0	0	0	0	0	0	0	0	0	0	WFDC12	WAP four-disulfide core domain 12 [Source:HGNC Symbol;Acc:HGNC:16115]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000168710	40.453	41.845	43.474	35.82	36.919	43.715	3309	3377	2626	2170	2551	2566	AHCYL1	adenosylhomocysteinase like 1 [Source:HGNC Symbol;Acc:HGNC:344]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K01251;K01251	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0004013//adenosylhomocysteinase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006378//mRNA polyadenylation;GO:0006611//protein export from nucleus;GO:0006730//one-carbon metabolic process;GO:0006915//apoptotic process;GO:0010765//positive regulation of sodium ion transport;GO:0031440//regulation of mRNA 3'-end processing;GO:0032412//regulation of ion transmembrane transporter activity;GO:0033353//S-adenosylmethionine cycle;GO:0038166//angiotensin-activated signaling pathway;GO:0042045//epithelial fluid transport;GO:0044070//regulation of anion transport;GO:0051592//response to calcium ion;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000168724	8.543	8.193	5.657	5.178	5.758	6.04	664.63	551.13	316.11	264.29	377.15	319.15	DNAJC21	DnaJ heat shock protein family (Hsp40) member C21 [Source:HGNC Symbol;Acc:HGNC:27030]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006457//protein folding	--
ENSG00000168734	33.025	31.839	32.49	34.016	29.791	34.773	816	789	593	627.86	623.83	625.7	PKIG	cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006469//negative regulation of protein kinase activity;GO:0016310//phosphorylation;GO:0042308//negative regulation of protein import into nucleus;GO:0051338//regulation of transferase activity;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000168743	1.694	1.088	1.224	2.302	2.8	1.641	112	103	73	123	158	109	NPNT	nephronectin [Source:HGNC Symbol;Acc:HGNC:27405]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06824	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016020//membrane;GO:0030485//smooth muscle contractile fiber;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding	GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033631//cell-cell adhesion mediated by integrin;GO:0045184//establishment of protein localization;GO:0045669//positive regulation of osteoblast differentiation;GO:0045987//positive regulation of smooth muscle contraction;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071356//cellular response to tumor necrosis factor;GO:0097195//pilomotor reflex;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	--
ENSG00000168748	0	0	0	0	0.038	0	0	0	0	0	1	0	CA7	carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:1381]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	"GO:0006730//one-carbon metabolic process;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032849//positive regulation of cellular pH reduction;GO:0051453//regulation of intracellular pH;GO:2001225//regulation of chloride transport"	--
ENSG00000168754	2.475	1.831	1.425	1.87	2.16	1.015	73	71	42	62	73	39	FAM178B	family with sequence similarity 178 member B [Source:HGNC Symbol;Acc:HGNC:28036]	-	-	-	-	-	-	-	--
ENSG00000168757	0	0	0	0	0	0	0	0	0	0	0	0	TSPY2	testis specific protein Y-linked 2 [Source:HGNC Symbol;Acc:HGNC:23924]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation	--
ENSG00000168758	14.781	14.507	11.087	15.695	16.015	15.292	886	918	576	757	846	753	SEMA4C	semaphorin 4C [Source:HGNC Symbol;Acc:HGNC:10731]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0001843//neural tube closure;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0021535//cell migration in hindbrain;GO:0021549//cerebellum development;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0042692//muscle cell differentiation;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000168763	11.242	11.499	12.372	12.856	12.846	15.391	1022	1070	856	882	1029	1028	CNNM3	cyclin and CBS domain divalent metal cation transport mediator 3 [Source:HGNC Symbol;Acc:HGNC:104]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0010960//magnesium ion homeostasis;GO:0055085//transmembrane transport	--
ENSG00000168765	12.489	12.786	15.765	19.309	17.118	18.015	370.2	377.87	337.38	422.13	420.12	381	GSTM4	glutathione S-transferase mu 4 [Source:HGNC Symbol;Acc:HGNC:4636]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0004364//glutathione transferase activity;GO:0004464//leukotriene-C4 synthase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding	GO:0006629//lipid metabolic process;GO:0006749//glutathione metabolic process;GO:0018916//nitrobenzene metabolic process;GO:0042178//xenobiotic catabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000168769	3.344	2.525	2.604	2.122	2.368	2.752	672	505	380	319	399	402	TET2	tet methylcytosine dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:25941]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0070579//methylcytosine dioxygenase activity	GO:0002521//leukocyte differentiation;GO:0006211//5-methylcytosine catabolic process;GO:0006325//chromatin organization;GO:0006493//protein O-linked glycosylation;GO:0006807//nitrogen compound metabolic process;GO:0007049//cell cycle;GO:0014070//response to organic cyclic compound;GO:0030099//myeloid cell differentiation;GO:0035511//oxidative DNA demethylation;GO:0043412//macromolecule modification;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:0080182//histone H3-K4 trimethylation	Others
ENSG00000168772	0.104	0.103	0.152	0.105	0.205	0.143	12	12	13	9	20	12	CXXC4	CXXC finger protein 4 [Source:HGNC Symbol;Acc:HGNC:24593]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K03344	GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000168778	12.12	13.426	11.293	8.584	8.531	8.641	653	693	442	341	375	339	TCTN2	tectonic family member 2 [Source:HGNC Symbol;Acc:HGNC:25774]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection;GO:0060170//ciliary membrane	-	GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1904491//protein localization to ciliary transition zone	--
ENSG00000168779	0	0.032	0	0	0	0	0	2	0	0	0	0	SHOX2	short stature homeobox 2 [Source:HGNC Symbol;Acc:HGNC:10854]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0002027//regulation of heart rate;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002062//chondrocyte differentiation;GO:0002063//chondrocyte development;GO:0003163//sinoatrial node development;GO:0003170//heart valve development;GO:0003172//sinoatrial valve development;GO:0003209//cardiac atrium morphogenesis;GO:0003213//cardiac right atrium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030326//embryonic limb morphogenesis;GO:0032330//regulation of chondrocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048557//embryonic digestive tract morphogenesis;GO:0048598//embryonic morphogenesis;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0050772//positive regulation of axonogenesis;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0060415//muscle tissue morphogenesis;GO:0060920//cardiac pacemaker cell differentiation;GO:0060931//sinoatrial node cell development;GO:2000172//regulation of branching morphogenesis of a nerve"	Homeobox
ENSG00000168781	7.101	5.899	7.442	10.03	5.866	5.395	550	563	450	515	546	433	PPIP5K1	diphosphoinositol pentakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:29023]	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K13024	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0000829//inositol heptakisphosphate kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0033857//diphosphoinositol-pentakisphosphate kinase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0102092//5-diphosphoinositol pentakisphosphate 3-kinase activity"	GO:0006020//inositol metabolic process;GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process	--
ENSG00000168785	57.155	59.784	65.091	65.786	58.93	67.754	3867	4111	3242	3287	3379	3390	TSPAN5	tetraspanin 5 [Source:HGNC Symbol;Acc:HGNC:17753]	-	-	-	-	GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0045747//positive regulation of Notch signaling pathway;GO:0051604//protein maturation;GO:0072659//protein localization to plasma membrane	--
ENSG00000168792	2.596	2.775	2.86	3.467	3.285	3.415	188	202	153	186	201	180	ABHD15	abhydrolase domain containing 15 [Source:HGNC Symbol;Acc:HGNC:26971]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane	GO:0005515//protein binding;GO:0034338//short-chain carboxylesterase activity;GO:0047372//acylglycerol lipase activity	GO:0044255//cellular lipid metabolic process	--
ENSG00000168795	10.948	10.861	10.982	10.02	10.841	12.306	1065	1062	789	722	891	871	ZBTB5	zinc finger and BTB domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23836]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000168802	27.455	29.27	29.791	29.379	32.049	27.425	1451.36	1616.11	1128.59	1179.12	1393.29	1131.16	CHTF8	chromosome transmission fidelity factor 8 [Source:HGNC Symbol;Acc:HGNC:24353]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031390//Ctf18 RFC-like complex	GO:0003677//DNA binding;GO:0003689//DNA clamp loader activity;GO:0017116//single-stranded DNA helicase activity	GO:0006260//DNA replication;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0032508//DNA duplex unwinding;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000168803	5.054	4.696	4.645	3.005	3.086	2.606	236	208	153	132	156	102	ADAL	adenosine deaminase like [Source:HGNC Symbol;Acc:HGNC:31853]	-	-	-	-	GO:0005829//cytosol	GO:0004000//adenosine deaminase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019239//deaminase activity;GO:0046872//metal ion binding;GO:0062154//N6-mAMP deaminase activity	GO:0006154//adenosine catabolic process;GO:0009117//nucleotide metabolic process;GO:0046103//inosine biosynthetic process;GO:0072521//purine-containing compound metabolic process	--
ENSG00000168806	4.222	4.883	5.45	3.886	4.162	5.374	272	294	260	179	249	246	LCMT2	leucine carboxyl methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:17558]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016740//transferase activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0031591//wybutosine biosynthetic process;GO:0032259//methylation	--
ENSG00000168807	5.431	4.785	5.464	4.678	4.183	5.895	1035	915	785	634	715	841	SNTB2	syntrophin beta 2 [Source:HGNC Symbol;Acc:HGNC:11169]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016020//membrane;GO:0030054//cell junction;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000168811	0.038	0.037	0.051	0	0	0	1	1	1	0	0	0	IL12A	interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: bacterial;Cardiovascular disease;Infectious disease: viral;Infectious disease: parasitic;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic;Immune disease;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic;Endocrine and metabolic disease	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05417//Lipid and atherosclerosis;ko05164//Influenza A;ko05146//Amoebiasis;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko04658//Th1 and Th2 cell differentiation;ko05133//Pertussis;ko04622//RIG-I-like receptor signaling pathway;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko05144//Malaria;ko04940//Type I diabetes mellitus	K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406;K05406	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031906//late endosome lumen;GO:0043514//interleukin-12 complex	GO:0005125//cytokine activity;GO:0005143//interleukin-12 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042163//interleukin-12 beta subunit binding;GO:0045513//interleukin-27 binding;GO:0046982//protein heterodimerization activity	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0006955//immune response;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0010224//response to UV-B;GO:0016477//cell migration;GO:0032496//response to lipopolysaccharide;GO:0032700//negative regulation of interleukin-17 production;GO:0032729//positive regulation of interferon-gamma production;GO:0032816//positive regulation of natural killer cell activation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045785//positive regulation of cell adhesion;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050709//negative regulation of protein secretion;GO:0050830//defense response to Gram-positive bacterium;GO:0051135//positive regulation of NK T cell activation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:2000510//positive regulation of dendritic cell chemotaxis	--
ENSG00000168813	5.392	4	3.992	3.415	3.748	4.493	818	580	411	382	432	471	ZNF507	zinc finger protein 507 [Source:HGNC Symbol;Acc:HGNC:23783]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046872//metal ion binding	GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000168818	10.366	9.18	7.169	8.759	6.664	8.301	455	413	237	275	252	263	STX18	syntaxin 18 [Source:HGNC Symbol;Acc:HGNC:15942]	Cellular Processes;Genetic Information Processing	"Transport and catabolism;Folding, sorting and degradation"	ko04145//Phagosome;ko04130//SNARE interactions in vesicular transport	K08492;K08492	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex	GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion;GO:0090158//endoplasmic reticulum membrane organization;GO:1902117//positive regulation of organelle assembly;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:1903358//regulation of Golgi organization"	--
ENSG00000168824	0.344	0.685	0.515	0.673	0.677	0.973	10	22	10	22	16	19	NSG1	neuronal vesicle trafficking associated 1 [Source:HGNC Symbol;Acc:HGNC:18790]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032580//Golgi cisterna membrane;GO:0032585//multivesicular body membrane;GO:0032588//trans-Golgi network membrane;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0043202//lysosomal lumen;GO:0045211//postsynaptic membrane;GO:0055038//recycling endosome membrane;GO:0098845//postsynaptic endosome;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0032051//clathrin light chain binding	"GO:0001881//receptor recycling;GO:0001921//positive regulation of receptor recycling;GO:0006915//apoptotic process;GO:0007212//dopamine receptor signaling pathway;GO:0016197//endosomal transport;GO:0042982//amyloid precursor protein metabolic process;GO:0048268//clathrin coat assembly;GO:0098814//spontaneous synaptic transmission;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse;GO:0099627//neurotransmitter receptor cycle;GO:0099630//postsynaptic neurotransmitter receptor cycle;GO:1900271//regulation of long-term synaptic potentiation"	--
ENSG00000168826	1.642	1.955	1.779	1.978	1.446	1.668	65	67	67	52	45	45	ZBTB49	zinc finger and BTB domain containing 49 [Source:HGNC Symbol;Acc:HGNC:19883]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle	ZBTB
ENSG00000168827	29.359	30.567	32.88	26.445	27.126	27.219	1562	1579	1183	1064	1131	1095	GFM1	G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0070125//mitochondrial translational elongation	--
ENSG00000168828	0	0	0	0	0	0	0	0	0	0	0	0	OR13J1	olfactory receptor family 13 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:15108]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000168830	0	0	0	0	0	0	0	0	0	0	0	0	HTR1E	5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse;ko04742//Taste transduction	K04153;K04153;K04153;K04153	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission"	--
ENSG00000168843	0.071	0.01	0.089	0.041	0.071	0.116	7	1	4	3	5	6	FSTL5	follistatin like 5 [Source:HGNC Symbol;Acc:HGNC:21386]	-	-	-	-	GO:0005576//extracellular region	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0030154//cell differentiation	--
ENSG00000168872	22.172	25.111	23.658	22.706	22.694	21.998	1241.58	1436.36	972.15	913.92	1088.99	933.46	DDX19A	DEAD-box helicase 19A [Source:HGNC Symbol;Acc:HGNC:25628]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K18655;K18655	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0008150//biological_process;GO:0016973//poly(A)+ mRNA export from nucleus	--
ENSG00000168874	0.528	0.653	0.404	0.725	0.666	0.785	62	77	35	63	66	67	ATOH8	atonal bHLH transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24126]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0001704//formation of primary germ layer;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0010595//positive regulation of endothelial cell migration;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0035148//tube formation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051450//myoblast proliferation;GO:0060395//SMAD protein signal transduction;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	bHLH
ENSG00000168875	0	0	0	0	0	0	0	0	0	0	0	0	SOX14	SRY-box transcription factor 14 [Source:HGNC Symbol;Acc:HGNC:11193]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0007601//visual perception;GO:0009649//entrainment of circadian clock;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:2001222//regulation of neuron migration"	HMG
ENSG00000168876	5.874	5.633	4.055	4.179	2.962	4.834	229	185	104	101	101	142	ANKRD49	ankyrin repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:25970]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000168878	0	0	0	0	0	0	0	0	0	0	0	0	SFTPB	surfactant protein B [Source:HGNC Symbol;Acc:HGNC:10801]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005771//multivesicular body;GO:0005789//endoplasmic reticulum membrane;GO:0042599//lamellar body;GO:0045334//clathrin-coated endocytic vesicle;GO:0097208//alveolar lamellar body;GO:0097486//multivesicular body lumen	GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009887//animal organ morphogenesis	--
ENSG00000168883	25.873	24.653	24.176	25.747	22.277	24.588	1102	989	730	794	815	773	USP39	ubiquitin specific peptidase 39 [Source:HGNC Symbol;Acc:HGNC:20071]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12847	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0046540//U4/U6 x U5 tri-snRNP complex	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0016579//protein deubiquitination;GO:0051301//cell division"	--
ENSG00000168884	9.016	9.202	7.697	10.031	8.997	9.606	361	370	227	294	304	280	TNIP2	TNFAIP3 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:19118]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0023035//CD40 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0050871//positive regulation of B cell activation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000168887	6.828	9.465	7.041	6.416	8.637	6.273	331	392	264	237	316.03	224	C2orf68	chromosome 2 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:34353]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000168890	10.082	11.369	11.88	11.28	11.049	13.021	325	373	288	277	304	298	TMEM150A	transmembrane protein 150A [Source:HGNC Symbol;Acc:HGNC:24677]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0009056//catabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0072659//protein localization to plasma membrane	--
ENSG00000168894	25.374	31.725	28.382	25.932	23.489	24.572	356	448	298	272	280	252	RNF181	ring finger protein 181 [Source:HGNC Symbol;Acc:HGNC:28037]	-	-	-	-	GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination	--
ENSG00000168899	1.68	3.779	3.066	4.043	2.68	4.317	23	52	31	41	31	43	VAMP5	vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08514	GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031301//integral component of organelle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0043001//Golgi to plasma membrane protein transport	--
ENSG00000168903	0	0	0	0	0	0	0	0	0	0	0	0	BTNL3	butyrophilin like 3 [Source:HGNC Symbol;Acc:HGNC:1143]	-	-	-	-	GO:0005575//cellular_component;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0008150//biological_process;GO:0050852//T cell receptor signaling pathway	--
ENSG00000168904	7.385	6.667	7.106	6.748	6.83	9.06	307	298	220	219	273.06	255	LRRC28	leucine rich repeat containing 28 [Source:HGNC Symbol;Acc:HGNC:28355]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000168906	62.542	57.869	76.604	63.884	66.181	97.992	3568	3323.41	3249.21	2707.63	3187.54	4075.2	MAT2A	methionine adenosyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:6904]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism	K00789;K00789;K00789	GO:0005829//cytosol;GO:0048269//methionine adenosyltransferase complex	GO:0000166//nucleotide binding;GO:0004478//methionine adenosyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006556//S-adenosylmethionine biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0034214//protein hexamerization;GO:0051291//protein heterooligomerization;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000168907	0.14	0.014	0.093	0	0	0	4	1	2	0	0	0	PLA2G4F	phospholipase A2 group IVF [Source:HGNC Symbol;Acc:HGNC:27396]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031982//vesicle;GO:0032587//ruffle membrane	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008970//phospholipase A1 activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0001516//prostaglandin biosynthetic process;GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0015908//fatty acid transport;GO:0016042//lipid catabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046475//glycerophospholipid catabolic process;GO:0050482//arachidonic acid secretion;GO:0071236//cellular response to antibiotic;GO:0071407//cellular response to organic cyclic compound	--
ENSG00000168913	3.33	3.266	2.984	3.735	2.831	2.256	71	70	47	59	51	35	ENHO	energy homeostasis associated [Source:HGNC Symbol;Acc:HGNC:24838]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000168916	14.437	13.011	14.433	9.406	12.581	14.072	1585	1445	1081	782	1126	1043	ZNF608	zinc finger protein 608 [Source:HGNC Symbol;Acc:HGNC:29238]	-	-	-	-	GO:0005634//nucleus	GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	Others
ENSG00000168917	2.206	2.58	2.46	2.08	2.427	2.626	81	91	61	52	72	68	SLC35G2	solute carrier family 35 member G2 [Source:HGNC Symbol;Acc:HGNC:28480]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000168918	0	0	0	0	0.016	0	0	0	0	0	1	0	INPP5D	inositol polyphosphate-5-phosphatase D [Source:HGNC Symbol;Acc:HGNC:6079]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Metabolism	Global and overview maps;Immune system;Immune system;Immune system;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K03084;K03084;K03084;K03084;K03084;K03084	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045121//membrane raft	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"	GO:0002376//immune system process;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008340//determination of adult lifespan;GO:0009968//negative regulation of signal transduction;GO:0016064//immunoglobulin mediated immune response;GO:0019637//organophosphate metabolic process;GO:0030853//negative regulation of granulocyte differentiation;GO:0030889//negative regulation of B cell proliferation;GO:0032715//negative regulation of interleukin-6 production;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0045579//positive regulation of B cell differentiation;GO:0045621//positive regulation of lymphocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045656//negative regulation of monocyte differentiation;GO:0045659//negative regulation of neutrophil differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:0046856//phosphatidylinositol dephosphorylation;GO:0050777//negative regulation of immune response;GO:0050852//T cell receptor signaling pathway;GO:0050869//negative regulation of B cell activation	--
ENSG00000168924	9.56	10.207	11.303	9.464	10.699	9.869	1065	1143	930	781	1007	800	LETM1	leucine zipper and EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6556]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015369//calcium:proton antiporter activity;GO:0043022//ribosome binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006875//cellular metal ion homeostasis;GO:0034214//protein hexamerization;GO:0042407//cristae formation;GO:0051260//protein homooligomerization;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051562//negative regulation of mitochondrial calcium ion concentration;GO:0099093//calcium export from the mitochondrion;GO:1900069//regulation of cellular hyperosmotic salinity response	--
ENSG00000168925	0	0	0	0	0.089	0	0	0	0	0	2	0	CTRB1	chymotrypsinogen B1 [Source:HGNC Symbol;Acc:HGNC:2521]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01310;K01310	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000168928	0	0	0	0.115	0	0	0	0	0	1	0	0	CTRB2	chymotrypsinogen B2 [Source:HGNC Symbol;Acc:HGNC:2522]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01310;K01310	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000168930	0	0	0	0	0	0	0	0	0	0	0	0	TRIM49	tripartite motif containing 49 [Source:HGNC Symbol;Acc:HGNC:13431]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000168936	23.981	25.073	25.509	27.285	28.62	31.397	1103	1119	914	905	1117	974	TMEM129	"transmembrane protein 129, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:25137]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol"	--
ENSG00000168938	27.428	25.037	26.896	25.672	24.767	26.572	776	712	562	538	592	547	PPIC	peptidylprolyl isomerase C [Source:HGNC Symbol;Acc:HGNC:9256]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000168939	0.586	0.35	0.28	0.47	0.384	0.403	66	39	28	35	43	35	SPRY3	sprouty RTK signaling antagonist 3 [Source:HGNC Symbol;Acc:HGNC:11271]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007275//multicellular organism development;GO:0007399//nervous system development;GO:0009966//regulation of signal transduction;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048513//animal organ development;GO:0061564//axon development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0150013//negative regulation of neuron projection arborization	--
ENSG00000168944	2.678	2.124	2.062	1.213	1.53	1.749	267	210	153	87	130	126	CEP120	centrosomal protein 120 [Source:HGNC Symbol;Acc:HGNC:26690]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0000226//microtubule cytoskeleton organization;GO:0007098//centrosome cycle;GO:0008283//cell population proliferation;GO:0010825//positive regulation of centrosome duplication;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0022027//interkinetic nuclear migration;GO:0030953//astral microtubule organization;GO:0032880//regulation of protein localization;GO:0032886//regulation of microtubule-based process;GO:0045724//positive regulation of cilium assembly;GO:1903724//positive regulation of centriole elongation;GO:1904951//positive regulation of establishment of protein localization	--
ENSG00000168952	2.074	1.98	1.747	3.088	1.608	2.921	127	84	66	126	92	133	STXBP6	syntaxin binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19666]	-	-	-	-	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane	"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0098641//cadherin binding involved in cell-cell adhesion"	GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport;GO:0035493//SNARE complex assembly;GO:0035542//regulation of SNARE complex assembly;GO:0045920//negative regulation of exocytosis;GO:0098609//cell-cell adhesion	--
ENSG00000168955	0.1	0	0.081	0	0.047	0	5	0	3	0	2	0	TM4SF20	transmembrane 4 L six family member 20 [Source:HGNC Symbol;Acc:HGNC:26230]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0045861//negative regulation of proteolysis	--
ENSG00000168958	43.44	38.866	42.842	46.013	43.7	48.696	1437	1345	1018	1028	1136	1171	MFF	mitochondrial fission factor [Source:HGNC Symbol;Acc:HGNC:24858]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031307//integral component of mitochondrial outer membrane;GO:0031410//cytoplasmic vesicle;GO:0032592//integral component of mitochondrial membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0000266//mitochondrial fission;GO:0001836//release of cytochrome c from mitochondria;GO:0006626//protein targeting to mitochondrion;GO:0008053//mitochondrial fusion;GO:0010821//regulation of mitochondrion organization;GO:0016559//peroxisome fission;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0070584//mitochondrion morphogenesis;GO:0090141//positive regulation of mitochondrial fission;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090314//positive regulation of protein targeting to membrane;GO:1900063//regulation of peroxisome organization	--
ENSG00000168959	0.049	0.006	0.015	0	0.007	0.015	5	1	1	0	1	1	GRM5	glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Signal transduction;Nervous system;Nervous system;Cellular community - eukaryotes;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04072//Phospholipase D signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04724//Glutamatergic synapse;ko04540//Gap junction;ko04720//Long-term potentiation	K04604;K04604;K04604;K04604;K04604;K04604;K04604;K04604;K04604;K04604	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0097449//astrocyte projection;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008066//glutamate receptor activity;GO:0030296//protein tyrosine kinase activator activity;GO:0031687//A2A adenosine receptor binding;GO:0042802//identical protein binding;GO:0099530//G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:0099583//neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:1990782//protein tyrosine kinase binding	"GO:0001932//regulation of protein phosphorylation;GO:0002029//desensitization of G protein-coupled receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006417//regulation of translation;GO:0006448//regulation of translational elongation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007206//phospholipase C-activating G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007611//learning or memory;GO:0007612//learning;GO:0007626//locomotory behavior;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0040013//negative regulation of locomotion;GO:0043410//positive regulation of MAPK cascade;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0050808//synapse organization;GO:0050890//cognition;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090647//modulation of age-related behavioral decline;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:0099553//trans-synaptic signaling by endocannabinoid, modulating synaptic transmission;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1902938//regulation of intracellular calcium activated chloride channel activity;GO:1904646//cellular response to amyloid-beta"	--
ENSG00000168961	5.777	7.262	7.232	3.037	4.927	2.378	171	232	129	72	117	57	LGALS9	galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0005534//galactose binding;GO:0016936//galactoside binding;GO:0019899//enzyme binding;GO:0030246//carbohydrate binding;GO:0048030//disaccharide binding	"GO:0002376//immune system process;GO:0002519//natural killer cell tolerance induction;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007565//female pregnancy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032496//response to lipopolysaccharide;GO:0032682//negative regulation of chemokine production;GO:0032689//negative regulation of interferon-gamma production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032834//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response;GO:0038066//p38MAPK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043305//negative regulation of mast cell degranulation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0046007//negative regulation of activated T cell proliferation;GO:0046598//positive regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060135//maternal process involved in female pregnancy;GO:0070241//positive regulation of activated T cell autonomous cell death;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070555//response to interleukin-1;GO:0071346//cellular response to interferon-gamma;GO:0071636//positive regulation of transforming growth factor beta production;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0098586//cellular response to virus;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:2001190//positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:2001200//positive regulation of dendritic cell differentiation;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"	--
ENSG00000168970	0.573	0.679	0.475	1.039	1.174	1.241	39.38	46.94	23.13	53.15	67.3	62.37	JMJD7-PLA2G4B	JMJD7-PLA2G4B readthrough [Source:HGNC Symbol;Acc:HGNC:34449]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	-	GO:0004620//phospholipase activity;GO:0005509//calcium ion binding;GO:0016706//2-oxoglutarate-dependent dioxygenase activity	GO:0009395//phospholipid catabolic process	--
ENSG00000168993	0.228	0.119	0.325	0.291	0.312	0.188	10	5	10	9	11	6	CPLX1	complexin 1 [Source:HGNC Symbol;Acc:HGNC:2309]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15294	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0031201//SNARE complex;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0070554//synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0016079//synaptic vesicle exocytosis;GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0046928//regulation of neurotransmitter secretion;GO:0098967//exocytic insertion of neurotransmitter receptor to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse	--
ENSG00000168994	18.389	20.458	19.152	15.215	14.859	18.1	706	801	551	439	489	513	PXDC1	PX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21361]	-	-	-	-	-	GO:0035091//phosphatidylinositol binding	-	--
ENSG00000168995	0	0	0.044	0.044	0	0.135	0	0	1	1	0	3	SIGLEC7	sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0038023//signaling receptor activity	GO:0007155//cell adhesion	--
ENSG00000169006	0	0	0	0	0	0	0	0	0	0	0	0	NTSR2	neurotensin receptor 2 [Source:HGNC Symbol;Acc:HGNC:8040]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04212	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0016492//G protein-coupled neurotensin receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007600//sensory perception;GO:0042391//regulation of membrane potential	--
ENSG00000169016	8.387	6.893	6.472	6.893	5.694	7.864	421	345	243	248	260	300	E2F6	E2F transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:3120]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0071339//MLL1 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0010468//regulation of gene expression"	E2F
ENSG00000169018	16.216	13.333	14.061	12.025	10.774	13.581	2414	1995	1546	1326	1355	1471	FEM1B	fem-1 homolog B [Source:HGNC Symbol;Acc:HGNC:3649]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005123//death receptor binding;GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0002070//epithelial cell maturation;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051438//regulation of ubiquitin-protein transferase activity;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000169019	6.006	5.515	6.479	6.014	4.453	6.939	182	168	145	135	114	153	COMMD8	COMM domain containing 8 [Source:HGNC Symbol;Acc:HGNC:26036]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000169020	33.414	30.394	27.791	35.443	28.627	29.303	210	192	129	165	152	134	ATP5ME	ATP synthase membrane subunit e [Source:HGNC Symbol;Acc:HGNC:846]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02129;K02129;K02129	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000169021	23.153	26.143	28.218	28.599	25.999	28.492	1482	1682	1334	1356	1406	1327	UQCRFS1	"ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:12587]"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411;K00411	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	"GO:0005515//protein binding;GO:0008121//ubiquinol-cytochrome-c reductase activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0022904//respiratory electron transport chain;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:1902600//proton transmembrane transport"	--
ENSG00000169026	0.413	0.77	0.737	0.794	0.538	0.619	14	22	18	20	16	16	SLC49A3	solute carrier family 49 member 3 [Source:HGNC Symbol;Acc:HGNC:26177]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000169031	1.547	1.361	1.919	1.312	1.832	1.978	245	228	207	162	258	240	COL4A3	collagen type IV alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2204]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0008015//blood circulation;GO:0008285//negative regulation of cell population proliferation;GO:0009749//response to glucose;GO:0010951//negative regulation of endopeptidase activity;GO:0016525//negative regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0032836//glomerular basement membrane development;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0072577//endothelial cell apoptotic process;GO:1905563//negative regulation of vascular endothelial cell proliferation	--
ENSG00000169032	18.516	19.477	19.811	20.247	22.018	22.595	926	984.94	747	743	946.9	833.91	MAP2K1	mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Infectious disease: viral;Signal transduction;Cancer: overview;Immune system;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cell growth and death;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Development and regeneration;Endocrine system;Nervous system;Signal transduction;Endocrine system;Signal transduction;Nervous system;Nervous system;Endocrine system;Signal transduction;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04660//T cell receptor signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368;K04368	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005078//MAP-kinase scaffold activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030295//protein kinase activator activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0047485//protein N-terminus binding;GO:0097110//scaffold protein binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021697//cerebellar cortex formation;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0030878//thyroid gland development;GO:0032147//activation of protein kinase activity;GO:0032872//regulation of stress-activated MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0045597//positive regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0048679//regulation of axon regeneration;GO:0048870//cell motility;GO:0050772//positive regulation of axonogenesis;GO:0060020//Bergmann glial cell differentiation;GO:0060324//face development;GO:0060425//lung morphogenesis;GO:0060440//trachea formation;GO:0060502//epithelial cell proliferation involved in lung morphogenesis;GO:0060674//placenta blood vessel development;GO:0060711//labyrinthine layer development;GO:0070371//ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090170//regulation of Golgi inheritance;GO:0090398//cellular senescence;GO:1903800//positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:2000641//regulation of early endosome to late endosome transport"	--
ENSG00000169035	0.091	0.091	0	0.209	0	0	2	2	0	2	0	0	KLK7	kallikrein related peptidase 7 [Source:HGNC Symbol;Acc:HGNC:6368]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0097209//epidermal lamellar body	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0002803//positive regulation of antibacterial peptide production;GO:0006508//proteolysis;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly	--
ENSG00000169045	79.671	73.752	85.157	68.057	75.305	92.281	3192	2997	2422	1912	2481	2528	HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing"	--
ENSG00000169047	4.855	4.104	5.358	5.702	6.144	7.066	984	836	802	856	1052	1042	IRS1	insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Neurodegenerative disease;Cardiovascular disease;Signal transduction;Cancer: overview;Endocrine and metabolic disease;Signal transduction;Transport and catabolism;Endocrine system;Signal transduction;Nervous system;Signal transduction;Endocrine system;Endocrine and metabolic disease;Aging;Endocrine system;Aging;Endocrine system;Endocrine and metabolic disease;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04931//Insulin resistance;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04930//Type II diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption"	K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172;K16172	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005899//insulin receptor complex;GO:0005901//caveola;GO:0043231//intracellular membrane-bounded organelle	GO:0001784//phosphotyrosine residue binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005080//protein kinase C binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0042169//SH2 domain binding;GO:0043548//phosphatidylinositol 3-kinase binding	GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0010907//positive regulation of glucose metabolic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0042593//glucose homeostasis;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0071398//cellular response to fatty acid	--
ENSG00000169057	16.245	15.965	16.034	15.93	15.749	14.505	2517	2305	1784	1879	2184	1826	MECP2	methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990]	-	-	-	-	GO:0000792//heterochromatin;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0045202//synapse;GO:0098794//postsynapse	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0010385//double-stranded methylated DNA binding;GO:0019904//protein domain specific binding;GO:0035197//siRNA binding;GO:0047485//protein N-terminus binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001662//behavioral fear response;GO:0001666//response to hypoxia;GO:0001964//startle response;GO:0001976//nervous system process involved in regulation of systemic arterial blood pressure;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006020//inositol metabolic process;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006541//glutamine metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0007052//mitotic spindle organization;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0007420//brain development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0007612//learning;GO:0007613//memory;GO:0007616//long-term memory;GO:0008104//protein localization;GO:0008211//glucocorticoid metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008306//associative learning;GO:0008344//adult locomotory behavior;GO:0008542//visual learning;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016358//dendrite development;GO:0016525//negative regulation of angiogenesis;GO:0016571//histone methylation;GO:0016573//histone acetylation;GO:0019230//proprioception;GO:0019233//sensory perception of pain;GO:0021549//cerebellum development;GO:0021591//ventricular system development;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0031507//heterochromatin assembly;GO:0032048//cardiolipin metabolic process;GO:0033555//multicellular organismal response to stress;GO:0035176//social behavior;GO:0040029//regulation of gene expression, epigenetic;GO:0042551//neuron maturation;GO:0043524//negative regulation of neuron apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046470//phosphatidylcholine metabolic process;GO:0048167//regulation of synaptic plasticity;GO:0050884//neuromuscular process controlling posture;GO:0050905//neuromuscular process;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0051570//regulation of histone H3-K9 methylation;GO:0051707//response to other organism;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0090063//positive regulation of microtubule nucleation;GO:1900114//positive regulation of histone H3-K9 trimethylation;GO:1905643//positive regulation of DNA methylation;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation"	MBD
ENSG00000169059	0	0	0	0	0	0	0	0	0	0	0	0	VCX3A	variable charge X-linked 3A [Source:HGNC Symbol;Acc:HGNC:18159]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	-	GO:0007420//brain development	--
ENSG00000169062	8.523	8.76	9.251	7.071	7.839	8.405	407	420	307	249	289	283	UPF3A	UPF3A regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:20332]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14328;K14328	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore;GO:0042162//telomeric DNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006913//nucleocytoplasmic transport;GO:0045727//positive regulation of translation;GO:0051028//mRNA transport"	--
ENSG00000169064	0.502	0.403	0.254	0.021	0.341	0	15	14	9	1	8	0	ZBBX	zinc finger B-box domain containing [Source:HGNC Symbol;Acc:HGNC:26245]	-	-	-	-	GO:0031514//motile cilium	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0003341//cilium movement	--
ENSG00000169067	0.069	0.069	0.07	0.07	0.061	0	4	4	3	3	3	0	ACTBL2	actin beta like 2 [Source:HGNC Symbol;Acc:HGNC:17780]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0016020//membrane;GO:0030424//axon;GO:0035267//NuA4 histone acetyltransferase complex;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0098973//structural constituent of postsynaptic actin cytoskeleton	GO:0007409//axonogenesis;GO:0008150//biological_process;GO:0048870//cell motility;GO:0098974//postsynaptic actin cytoskeleton organization	--
ENSG00000169071	14.697	13.949	18.842	17.313	18.958	18.74	1265	1208	1199	1099	1379	1170	ROR2	receptor tyrosine kinase like orphan receptor 2 [Source:HGNC Symbol;Acc:HGNC:10257]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K05123	GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0043025//neuronal cell body;GO:0043235//receptor complex	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017147//Wnt-protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0046872//metal ion binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	"GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007275//multicellular organism development;GO:0008285//negative regulation of cell population proliferation;GO:0010976//positive regulation of neuron projection development;GO:0014002//astrocyte development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030282//bone mineralization;GO:0030335//positive regulation of cell migration;GO:0030539//male genitalia development;GO:0033674//positive regulation of kinase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0045651//positive regulation of macrophage differentiation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:1900020//positive regulation of protein kinase C activity;GO:1905517//macrophage migration"	--
ENSG00000169083	0.672	0.54	0.655	0.256	0.535	0.317	94	115	74	42	50	51	AR	androgen receptor [Source:HGNC Symbol;Acc:HGNC:644]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Cancer: overview;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04114//Oocyte meiosis;ko05215//Prostate cancer	K08557;K08557;K08557;K08557	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005102//signaling receptor binding;GO:0005496//steroid binding;GO:0005497//androgen binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070974//POU domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0003073//regulation of systemic arterial blood pressure;GO:0003382//epithelial cell morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009566//fertilization;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0019102//male somatic sex determination;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0030522//intracellular receptor signaling pathway;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0033327//Leydig cell differentiation;GO:0035264//multicellular organism growth;GO:0042327//positive regulation of phosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0045720//negative regulation of integrin biosynthetic process;GO:0045726//positive regulation of integrin biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0048608//reproductive structure development;GO:0048638//regulation of developmental growth;GO:0048645//animal organ formation;GO:0048808//male genitalia morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060520//activation of prostate induction by androgen receptor signaling pathway;GO:0060571//morphogenesis of an epithelial fold;GO:0060599//lateral sprouting involved in mammary gland duct morphogenesis;GO:0060685//regulation of prostatic bud formation;GO:0060736//prostate gland growth;GO:0060740//prostate gland epithelium morphogenesis;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0060748//tertiary branching involved in mammary gland duct morphogenesis;GO:0060749//mammary gland alveolus development;GO:0060769//positive regulation of epithelial cell proliferation involved in prostate gland development;GO:0061458//reproductive system development;GO:0071383//cellular response to steroid hormone stimulus;GO:0071391//cellular response to estrogen stimulus;GO:0071394//cellular response to testosterone stimulus;GO:0072520//seminiferous tubule development;GO:1903076//regulation of protein localization to plasma membrane;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	ESR-like
ENSG00000169084	15.995	16.047	18.334	17.134	15.093	20.879	565.66	591.92	446	479	502	504	DHRSX	dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0010508//positive regulation of autophagy	--
ENSG00000169085	0.175	0.301	0	0.156	0.339	0.05	11.48	19.4	0	4.96	13.36	2.37	VXN	vexin [Source:HGNC Symbol;Acc:HGNC:28498]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0030182//neuron differentiation	--
ENSG00000169087	1.89	2.271	2.127	1.657	1.83	2.564	77	93	64	50	63	76	HSPBAP1	HSPB1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16389]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0016706//2-oxoglutarate-dependent dioxygenase activity	-	--
ENSG00000169093	17.523	17.106	17.312	19.638	17.108	15.378	749	736	547	622	618	479	ASMTL	acetylserotonin O-methyltransferase like [Source:HGNC Symbol;Acc:HGNC:751]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K25435;K25435	GO:0005829//cytosol	GO:0003674//molecular_function;GO:0004551//nucleotide diphosphatase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0036218//dTTP diphosphatase activity;GO:0036221//UTP diphosphatase activity;GO:0047429//nucleoside-triphosphate diphosphatase activity	GO:0008150//biological_process;GO:0009117//nucleotide metabolic process;GO:0032259//methylation	--
ENSG00000169100	294.319	307.92	313.07	412.407	363.586	332.581	8858	9315	6959	9194	9245	7283	SLC25A6	solute carrier family 25 member 6 [Source:HGNC Symbol;Acc:HGNC:10992]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia	K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863;K05863	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0006915//apoptotic process;GO:0055085//transmembrane transport;GO:0140021//mitochondrial ADP transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport	--
ENSG00000169105	12.502	13.651	14.556	13.795	15.637	15.903	564	619	485	461	596	522	CHST14	carbohydrate sulfotransferase 14 [Source:HGNC Symbol;Acc:HGNC:24464]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K08105	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0098791//Golgi apparatus subcompartment	GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0042301//phosphate ion binding	GO:0005975//carbohydrate metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0050655//dermatan sulfate proteoglycan metabolic process	--
ENSG00000169116	105.814	104.954	110.492	83.991	94.263	104.957	10985	10945	8470	6448	8257	7928	PARM1	prostate androgen-regulated mucin-like protein 1 [Source:HGNC Symbol;Acc:HGNC:24536]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0051973//positive regulation of telomerase activity	--
ENSG00000169118	7.838	5.892	5.846	4.55	5.225	6.093	816.59	771	572	475.91	639.96	583.7	CSNK1G1	casein kinase 1 gamma 1 [Source:HGNC Symbol;Acc:HGNC:2454]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K08958	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000169122	5.931	6.803	5.331	6.059	6.662	7.067	412	475	274	313	391	358	FAM110B	family with sequence similarity 110 member B [Source:HGNC Symbol;Acc:HGNC:28587]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000169126	0.4	0.274	0.236	0.374	0.18	0.33	13	14	7	10	11	7	ODAD2	outer dynein arm docking complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25583]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0003356//regulation of cilium beat frequency;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0021591//ventricular system development;GO:0030030//cell projection organization;GO:0036158//outer dynein arm assembly	--
ENSG00000169129	0.039	0.129	0	0.148	0.086	0.171	3	10	0	9	6	8	AFAP1L2	actin filament associated protein 1 like 2 [Source:HGNC Symbol;Acc:HGNC:25901]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0017124//SH3 domain binding;GO:0030296//protein tyrosine kinase activator activity;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding	"GO:0006954//inflammatory response;GO:0007346//regulation of mitotic cell cycle;GO:0009966//regulation of signal transduction;GO:0032675//regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061098//positive regulation of protein tyrosine kinase activity"	--
ENSG00000169131	4.215	3.68	3.692	2.838	3.681	3.405	220.41	189.64	142.6	109.92	139.21	114	ZNF354A	zinc finger protein 354A [Source:HGNC Symbol;Acc:HGNC:11628]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007605//sensory perception of sound"	zf-C2H2
ENSG00000169136	7.258	8.63	9.019	10.006	8.086	8.585	277.77	346	266.97	280.91	282.85	250	ATF5	activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0008285//negative regulation of cell population proliferation;GO:0009791//post-embryonic development;GO:0010468//regulation of gene expression;GO:0021889//olfactory bulb interneuron differentiation;GO:0021891//olfactory bulb interneuron development;GO:0021930//cerebellar granule cell precursor proliferation;GO:0021988//olfactory lobe development;GO:0035264//multicellular organism growth;GO:0043066//negative regulation of apoptotic process;GO:0045444//fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046605//regulation of centrosome cycle;GO:1902750//negative regulation of cell cycle G2/M phase transition"	TF_bZIP
ENSG00000169139	21.002	18.949	18.121	16.48	14.29	18.715	818	735	549	482	499	538	UBE2V2	ubiquitin conjugating enzyme E2 V2 [Source:HGNC Symbol;Acc:HGNC:12495]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K10704	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031372//UBC13-MMS2 complex;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0000729//DNA double-strand break processing;GO:0006282//regulation of DNA repair;GO:0006301//postreplication repair;GO:0016567//protein ubiquitination;GO:0042275//error-free postreplication DNA repair;GO:0070534//protein K63-linked ubiquitination;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000169154	0	0	0	0	0	0	0	0	0	0	0	0	GOT1L1	glutamic-oxaloacetic transaminase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28487]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00330//Arginine and proline metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko00350//Tyrosine metabolism;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism;ko00360//Phenylalanine metabolism;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454;K14454	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006520//cellular amino acid metabolic process;GO:0006532//aspartate biosynthetic process;GO:0009058//biosynthetic process	--
ENSG00000169155	4.121	3.456	4.022	3.295	3.481	4.491	407	428	366	299	362	316	ZBTB43	zinc finger and BTB domain containing 43 [Source:HGNC Symbol;Acc:HGNC:17908]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001025//RNA polymerase III general transcription initiation factor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000169169	31.844	34.294	39.796	32.576	34.864	41.972	1789	1828	1583	1367	1560	1696	CPT1C	carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540]	Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Environmental adaptation;Endocrine and metabolic disease;Signal transduction;Endocrine system;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism	ko04714//Thermogenesis;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K19524;K19524;K19524;K19524;K19524;K19524;K19524;K19524	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032281//AMPA glutamate receptor complex;GO:0042995//cell projection;GO:0045202//synapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0004095//carnitine O-palmitoyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0009437//carnitine metabolic process;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels	--
ENSG00000169174	2.994	1.907	2.118	1.942	2.168	2.327	165	133	118	104	124	123	PCSK9	proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K13050	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0036020//endolysosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990666//PCSK9-LDLR complex;GO:1990667//PCSK9-AnxA2 complex	GO:0003723//RNA binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019871//sodium channel inhibitor activity;GO:0030169//low-density lipoprotein particle binding;GO:0030547//signaling receptor inhibitor activity;GO:0034185//apolipoprotein binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0034190//apolipoprotein receptor binding;GO:0043621//protein self-association;GO:0050750//low-density lipoprotein particle receptor binding;GO:0070326//very-low-density lipoprotein particle receptor binding	GO:0001822//kidney development;GO:0001889//liver development;GO:0001920//negative regulation of receptor recycling;GO:0002091//negative regulation of receptor internalization;GO:0002092//positive regulation of receptor internalization;GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006644//phospholipid metabolic process;GO:0006915//apoptotic process;GO:0007041//lysosomal transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009267//cellular response to starvation;GO:0010469//regulation of signaling receptor activity;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0016485//protein processing;GO:0016540//protein autoprocessing;GO:0022008//neurogenesis;GO:0030182//neuron differentiation;GO:0032799//low-density lipoprotein receptor particle metabolic process;GO:0032802//low-density lipoprotein particle receptor catabolic process;GO:0032803//regulation of low-density lipoprotein particle receptor catabolic process;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0043523//regulation of neuron apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:1905596//negative regulation of low-density lipoprotein particle receptor binding;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:1905601//negative regulation of receptor-mediated endocytosis involved in cholesterol transport;GO:2000272//negative regulation of signaling receptor activity;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000169180	27.828	28.033	31.605	40.917	29.479	30.357	2329	2378	1785	1659	2061	1742	XPO6	exportin 6 [Source:HGNC Symbol;Acc:HGNC:19733]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K25204	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0033036//macromolecule localization;GO:0071702//organic substance transport	--
ENSG00000169181	0	0.245	0.053	0.075	0	0	0	6	2	4	0	0	GSG1L	GSG1 like [Source:HGNC Symbol;Acc:HGNC:28283]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032279//asymmetric synapse;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000169184	4.105	4.512	3.776	3.207	4.28	3.96	601	735	452	385	582	467	MN1	"MN1 proto-oncogene, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:7180]"	-	-	-	-	GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0001957//intramembranous ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0033689//negative regulation of osteoblast proliferation;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:1902806//regulation of cell cycle G1/S phase transition"	--
ENSG00000169188	4.599	5.612	4.716	6.169	6.36	5.851	309	379	234	307	361	286	APEX2	apurinic/apyrimidinic endodeoxyribonuclease 2 [Source:HGNC Symbol;Acc:HGNC:17889]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10772	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0008311//double-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000169189	26.163	26.482	26.541	32.354	24.141	20.84	556	569	426	439	435	319	NSMCE1	"NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897]"	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0030915//Smc5-Smc6 complex;GO:0043231//intracellular membrane-bounded organelle"	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0061630//ubiquitin protein ligase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0032204//regulation of telomere maintenance;GO:2001022//positive regulation of response to DNA damage stimulus	--
ENSG00000169193	5.557	5.196	5.75	5.031	4.66	6.274	241	219	188	180	175	192	CCDC126	coiled-coil domain containing 126 [Source:HGNC Symbol;Acc:HGNC:22398]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane	-	-	--
ENSG00000169194	0	0	0	0	0	0	0	0	0	0	0	0	IL13	interleukin 13 [Source:HGNC Symbol;Acc:HGNC:5973]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signaling molecules and interaction;Signal transduction;Immune system;Immune disease;Immune system;Immune system;Immune disease	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04657//IL-17 signaling pathway;ko05321//Inflammatory bowel disease	K05435;K05435;K05435;K05435;K05435;K05435;K05435;K05435	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005144//interleukin-13 receptor binding;GO:0005515//protein binding	GO:0001774//microglial cell activation;GO:0002639//positive regulation of immunoglobulin production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0009612//response to mechanical stimulus;GO:0010155//regulation of proton transport;GO:0010628//positive regulation of gene expression;GO:0030890//positive regulation of B cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0032723//positive regulation of connective tissue growth factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0035094//response to nicotine;GO:0042116//macrophage activation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043032//positive regulation of macrophage activation;GO:0043270//positive regulation of ion transport;GO:0043306//positive regulation of mast cell degranulation;GO:0045471//response to ethanol;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050728//negative regulation of inflammatory response;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0071260//cellular response to mechanical stimulus;GO:0071345//cellular response to cytokine stimulus;GO:0071635//negative regulation of transforming growth factor beta production;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901215//negative regulation of neuron death;GO:1901247//negative regulation of lung ciliated cell differentiation;GO:1901251//positive regulation of lung goblet cell differentiation;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:2000231//positive regulation of pancreatic stellate cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000169203	7.47	3.118	6.933	7.016	5.595	4.692	194.93	120.98	138.75	151.5	171.4	111.45	NPIPB12	nuclear pore complex interacting protein family member B12 [Source:HGNC Symbol;Acc:HGNC:37491]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000169208	0	0	0	0	0	0	0	0	0	0	0	0	OR10G3	olfactory receptor family 10 subfamily G member 3 [Source:HGNC Symbol;Acc:HGNC:8171]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000169213	0.702	0.66	0.461	0.349	0.319	0.436	186.21	175.86	90.29	68.47	71.37	84.17	RAB3B	"RAB3B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9778]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098691//dopaminergic synapse;GO:0098993//anchored component of synaptic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0031489//myosin V binding	GO:0006904//vesicle docking involved in exocytosis;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0019882//antigen processing and presentation;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0072659//protein localization to plasma membrane;GO:0097494//regulation of vesicle size;GO:0098693//regulation of synaptic vesicle cycle	--
ENSG00000169214	0	0	0	0	0	0	0	0	0	0	0	0	OR6F1	olfactory receptor family 6 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:15027]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000169217	26.517	26.236	29.461	31.264	27.643	28.473	1458	1557	1216	1253	1288	1235	CD2BP2	CD2 cytoplasmic tail binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1656]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005682//U5 snRNP;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000169218	0.02	0.021	0	0.028	0	0	1	1	0	1	0	0	RSPO1	R-spondin 1 [Source:HGNC Symbol;Acc:HGNC:21679]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K19471	GO:0005576//extracellular region;GO:0005634//nucleus	GO:0001664//G protein-coupled receptor binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002090//regulation of receptor internalization;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0050896//response to stimulus;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000169220	5.576	6.655	7.306	6.5	6.344	7.494	230	271	219	196	222	213	RGS14	regulator of G protein signaling 14 [Source:HGNC Symbol;Acc:HGNC:9996]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17706	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016605//PML body;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030695//GTPase regulator activity;GO:0032794//GTPase activating protein binding	GO:0000278//mitotic cell cycle;GO:0006913//nucleocytoplasmic transport;GO:0006979//response to oxidative stress;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007059//chromosome segregation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007612//learning;GO:0007616//long-term memory;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0008542//visual learning;GO:0009968//negative regulation of signal transduction;GO:0010070//zygote asymmetric cell division;GO:0031914//negative regulation of synaptic plasticity;GO:0035556//intracellular signal transduction;GO:0043407//negative regulation of MAP kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050769//positive regulation of neurogenesis;GO:0050790//regulation of catalytic activity;GO:0050804//modulation of chemical synaptic transmission;GO:0051301//cell division;GO:0060291//long-term synaptic potentiation;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000169221	19.114	19.856	20.768	21.287	23.234	21.592	1404	1433	1139	1158	1426	1142	TBC1D10B	TBC1 domain family member 10B [Source:HGNC Symbol;Acc:HGNC:24510]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0042147//retrograde transport, endosome to Golgi;GO:0043087//regulation of GTPase activity;GO:0090630//activation of GTPase activity"	--
ENSG00000169223	115.092	125.38	114.896	136.935	132.415	119.875	3222	3678	2500	3026	3171	2470	LMAN2	"lectin, mannose binding 2 [Source:HGNC Symbol;Acc:HGNC:16986]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10082	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0031072//heat shock protein binding;GO:0046872//metal ion binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0050766//positive regulation of phagocytosis"	--
ENSG00000169224	0	0	0	0	0	0	0	0	0	0	0	0	GCSAML	germinal center associated signaling and motility like [Source:HGNC Symbol;Acc:HGNC:29583]	-	-	-	-	-	GO:0005515//protein binding	GO:0050855//regulation of B cell receptor signaling pathway;GO:2000401//regulation of lymphocyte migration	--
ENSG00000169228	16.329	16.173	18.648	17.494	16.777	22.618	467	459	395	366	408	471	RAB24	"RAB24, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9765]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0030667//secretory granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0015031//protein transport	--
ENSG00000169230	59.235	66.297	61.653	69.907	59.723	65.082	1503.84	1693.81	1155.95	1302.83	1280.91	1195	PRELID1	PRELI domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30255]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:1990050//phosphatidic acid transfer activity	GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007275//multicellular organism development;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0010950//positive regulation of endopeptidase activity;GO:0015914//phospholipid transport;GO:0043066//negative regulation of apoptotic process;GO:0045580//regulation of T cell differentiation;GO:0051881//regulation of mitochondrial membrane potential;GO:0070234//positive regulation of T cell apoptotic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097035//regulation of membrane lipid distribution;GO:0120009//intermembrane lipid transfer;GO:1901857//positive regulation of cellular respiration;GO:2001140//positive regulation of phospholipid transport	--
ENSG00000169231	8.427	10.635	6.675	6.559	8.495	7.764	548	698	321	315	466	367	THBS3	thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Transport and catabolism;Cellular community - eukaryotes;Signaling molecules and interaction;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko04510//Focal adhesion;ko04512//ECM-receptor interaction;ko05144//Malaria	K04659;K04659;K04659;K04659;K04659;K04659	GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0003417//growth plate cartilage development;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0043931//ossification involved in bone maturation;GO:0060346//bone trabecula formation	--
ENSG00000169239	11.017	10.081	9.859	5.058	10.03	9.75	707	655	481	291	408	365	CA5B	carbonic anhydrase 5B [Source:HGNC Symbol;Acc:HGNC:1378]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process;GO:0009617//response to bacterium	--
ENSG00000169241	24.729	26.235	25.975	23.742	25.742	26.733	627	678	489	448	543	490	SLC50A1	solute carrier family 50 member 1 [Source:HGNC Symbol;Acc:HGNC:30657]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042947//glucoside transmembrane transporter activity;GO:0051119//sugar transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0042946//glucoside transport	--
ENSG00000169242	5.188	6.768	4.206	4.068	4.204	3.245	167	219	100	97	114	76	EFNA1	ephrin A1 [Source:HGNC Symbol;Acc:HGNC:3221]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0003180//aortic valve morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0007267//cell-cell signaling;GO:0007411//axon guidance;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0014028//notochord formation;GO:0016477//cell migration;GO:0030182//neuron differentiation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043409//negative regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050770//regulation of axonogenesis;GO:0050821//protein stabilization;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070244//negative regulation of thymocyte apoptotic process;GO:1902004//positive regulation of amyloid-beta formation;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1903051//negative regulation of proteolysis involved in cellular protein catabolic process	--
ENSG00000169245	0	0.041	0	0	0.194	0	0	1	0	0	4	0	CXCL10	C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Signal transduction;Immune system;Signaling molecules and interaction;Immune system;Immune system;Immune system	ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko04062//Chemokine signaling pathway;ko05164//Influenza A;ko05160//Hepatitis C;ko04668//TNF signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12671;K12671;K12671;K12671;K12671;K12671;K12671;K12671;K12671;K12671;K12671;K12671	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0042056//chemoattractant activity;GO:0045236//CXCR chemokine receptor binding;GO:0048248//CXCR3 chemokine receptor binding	GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007517//muscle organ development;GO:0008015//blood circulation;GO:0008284//positive regulation of cell population proliferation;GO:0009409//response to cold;GO:0009615//response to virus;GO:0009617//response to bacterium;GO:0010332//response to gamma radiation;GO:0010818//T cell chemotaxis;GO:0010819//regulation of T cell chemotaxis;GO:0010996//response to auditory stimulus;GO:0016525//negative regulation of angiogenesis;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0032496//response to lipopolysaccharide;GO:0033280//response to vitamin D;GO:0034605//cellular response to heat;GO:0042118//endothelial cell activation;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0045662//negative regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0050918//positive chemotaxis;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051607//defense response to virus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0098586//cellular response to virus;GO:0140374//antiviral innate immune response;GO:1901509//regulation of endothelial tube morphogenesis;GO:1901740//negative regulation of myoblast fusion;GO:2000406//positive regulation of T cell migration	--
ENSG00000169246	13.143	9.94	11.082	14.701	15.369	15.285	365.85	274.93	227.18	292.14	350.9	278.55	NPIPB3	nuclear pore complex interacting protein family member B3 [Source:HGNC Symbol;Acc:HGNC:28989]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000169247	1.865	1.77	2.037	3.213	3.139	3.723	236	207	249	325	395	387	SH3TC2	SH3 domain and tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:29427]	-	-	-	-	GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0022011//myelination in peripheral nervous system;GO:0032287//peripheral nervous system myelin maintenance;GO:0033157//regulation of intracellular protein transport;GO:1901184//regulation of ERBB signaling pathway	--
ENSG00000169248	0	0	0	0	0.193	0.09	0	0	0	0	5	2	CXCL11	C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K12672;K12672;K12672;K12672	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0045236//CXCR chemokine receptor binding;GO:0048248//CXCR3 chemokine receptor binding	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010818//T cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0042127//regulation of cell population proliferation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000169249	3.609	3.941	3.391	2.342	2.86	2.784	357.48	201.11	192.18	170.95	197.64	212.3	ZRSR2	"zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 [Source:HGNC Symbol;Acc:HGNC:23019]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000169251	20.864	18.831	17.994	12.145	12.815	14.584	1128	955	673	455	531	515	NMD3	NMD3 ribosome export adaptor [Source:HGNC Symbol;Acc:HGNC:24250]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03008//Ribosome biogenesis in eukaryotes	K07562;K07562	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003723//RNA binding;GO:0030674//protein-macromolecule adaptor activity;GO:0043023//ribosomal large subunit binding	GO:0000055//ribosomal large subunit export from nucleus;GO:0015031//protein transport;GO:0032092//positive regulation of protein binding;GO:1902680//positive regulation of RNA biosynthetic process;GO:1904751//positive regulation of protein localization to nucleolus	--
ENSG00000169252	0.91	0.882	0.876	1.196	0.822	1.646	38	37	27	37	29	50	ADRB2	adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:286]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Circulatory system;Digestive system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04970//Salivary secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K04142;K04142;K04142;K04142;K04142;K04142;K04142;K04142;K04142	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0043235//receptor complex	GO:0001540//amyloid-beta binding;GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004941//beta2-adrenergic receptor activity;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0015459//potassium channel regulator activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0051380//norepinephrine binding	GO:0001993//regulation of systemic arterial blood pressure by norepinephrine-epinephrine;GO:0002024//diet induced thermogenesis;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0002028//regulation of sodium ion transport;GO:0002032//desensitization of G protein-coupled receptor signaling pathway by arrestin;GO:0006898//receptor-mediated endocytosis;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0008333//endosome to lysosome transport;GO:0009409//response to cold;GO:0010739//positive regulation of protein kinase A signaling;GO:0030501//positive regulation of bone mineralization;GO:0031649//heat generation;GO:0040015//negative regulation of multicellular organism growth;GO:0043410//positive regulation of MAPK cascade;GO:0045453//bone resorption;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045986//negative regulation of smooth muscle contraction;GO:0050873//brown fat cell differentiation;GO:0061885//positive regulation of mini excitatory postsynaptic potential;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0097746//blood vessel diameter maintenance;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901098//positive regulation of autophagosome maturation;GO:1904504//positive regulation of lipophagy;GO:1904646//cellular response to amyloid-beta;GO:1990911//response to psychosocial stress;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:2000969//positive regulation of AMPA receptor activity	--
ENSG00000169255	14.31	14.09	12.087	12.417	11.917	12.806	727	763	484	507	535	473	B3GALNT1	"beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) [Source:HGNC Symbol;Acc:HGNC:918]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K00719;K00719;K00719	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047273//galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0009312//oligosaccharide biosynthetic process	--
ENSG00000169258	0.444	0.646	0.355	0.523	0.445	0.438	39	57	23	34	33	28	GPRIN1	G protein regulated inducer of neurite outgrowth 1 [Source:HGNC Symbol;Acc:HGNC:24835]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030426//growth cone;GO:0042995//cell projection	GO:0005515//protein binding;GO:0051219//phosphoprotein binding	GO:0031175//neuron projection development	--
ENSG00000169271	14.698	17.166	11.248	12.078	10.001	13.076	207	243	117	126	119	134	HSPB3	heat shock protein family B (small) member 3 [Source:HGNC Symbol;Acc:HGNC:5248]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	-	GO:0006986//response to unfolded protein	--
ENSG00000169282	2.972	2.843	3.313	3.37	2.692	2.484	228	216	189	190	193	129	KCNAB1	potassium voltage-gated channel subfamily A regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0034705//potassium channel complex;GO:0044224//juxtaparanode region of axon	GO:0004033//aldo-keto reductase (NADP) activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0015459//potassium channel regulator activity;GO:0016491//oxidoreductase activity;GO:0019904//protein domain specific binding;GO:0044325//transmembrane transporter binding;GO:0070402//NADPH binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1901379//regulation of potassium ion transmembrane transport;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:1903817//negative regulation of voltage-gated potassium channel activity	--
ENSG00000169288	5.457	4.531	6.056	5.318	5.148	3.553	133	111	109	96	106	63	MRPL1	mitochondrial ribosomal protein L1 [Source:HGNC Symbol;Acc:HGNC:14275]	Genetic Information Processing	Translation	ko03010//Ribosome	K02863	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0022625//cytosolic large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0000470//maturation of LSU-rRNA;GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000169291	0	0.007	0	0.188	0.035	0.01	0	1	0	2	4	1	SHE	Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004]	-	-	-	-	-	GO:0001784//phosphotyrosine residue binding;GO:0005515//protein binding	-	--
ENSG00000169297	0	0	0	0	0	0	0	0	0	0	0	0	NR0B1	nuclear receptor subfamily 0 group B member 1 [Source:HGNC Symbol;Acc:HGNC:7960]	Organismal Systems	Endocrine system	ko04927//Cortisol synthesis and secretion	K08562	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0034451//centriolar satellite;GO:0042788//polysomal ribosome;GO:0043231//intracellular membrane-bounded organelle	GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019904//protein domain specific binding;GO:0032448//DNA hairpin binding;GO:0042803//protein homodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007530//sex determination;GO:0008104//protein localization;GO:0008406//gonad development;GO:0008584//male gonad development;GO:0010894//negative regulation of steroid biosynthetic process;GO:0021854//hypothalamus development;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030238//male sex determination;GO:0030325//adrenal gland development;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0033327//Leydig cell differentiation;GO:0035902//response to immobilization stress;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060008//Sertoli cell differentiation"	Miscellaneous
ENSG00000169299	10.249	10.493	9.878	8.552	9.091	12.009	558	511	404	313	380	376	PGM2	phosphoglucomutase 2 [Source:HGNC Symbol;Acc:HGNC:8906]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00010//Glycolysis / Gluconeogenesis;ko00520//Amino sugar and nucleotide sugar metabolism;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism;ko00030//Pentose phosphate pathway	K15779;K15779;K15779;K15779;K15779;K15779;K15779	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity;GO:0005515//protein binding;GO:0008973//phosphopentomutase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0046386//deoxyribose phosphate catabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000169302	0.132	0.255	0.162	0.302	0.246	0.298	9	20	10	6	21	14	STK32A	serine/threonine kinase 32A [Source:HGNC Symbol;Acc:HGNC:28317]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000169306	0.315	0.209	0.09	0.224	0.101	0.115	23	11	5	9	5	5	IL1RAPL1	interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse	"GO:0003953//NAD+ nucleosidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0010975//regulation of neuron projection development;GO:0030182//neuron differentiation;GO:0045920//negative regulation of exocytosis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0051965//positive regulation of synapse assembly;GO:0071345//cellular response to cytokine stimulus;GO:0097105//presynaptic membrane assembly;GO:0099175//regulation of postsynapse organization;GO:0099545//trans-synaptic signaling by trans-synaptic complex;GO:1905606//regulation of presynapse assembly	--
ENSG00000169313	0	0	0	0	0	0	0	0	0	0	0	0	P2RY12	purinergic receptor P2Y12 [Source:HGNC Symbol;Acc:HGNC:18124]	Organismal Systems	Immune system	ko04611//Platelet activation	K04298	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0031253//cell projection membrane;GO:0044298//cell body membrane	GO:0001609//G protein-coupled adenosine receptor activity;GO:0001621//G protein-coupled ADP receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	"GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0006930//substrate-dependent cell migration, cell extension;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0019722//calcium-mediated signaling;GO:0021808//cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration;GO:0030030//cell projection organization;GO:0030032//lamellipodium assembly;GO:0030168//platelet activation;GO:0033626//positive regulation of integrin activation by cell surface receptor linked signal transduction;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0043270//positive regulation of ion transport;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048678//response to axon injury;GO:0050920//regulation of chemotaxis;GO:0050921//positive regulation of chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0070527//platelet aggregation;GO:0071318//cellular response to ATP;GO:0071407//cellular response to organic cyclic compound;GO:0150063//visual system development;GO:1900029//positive regulation of ruffle assembly;GO:1904139//regulation of microglial cell migration;GO:1904141//positive regulation of microglial cell migration"	--
ENSG00000169314	0.071	0	0	0.145	0.128	0	1	0	0	2	2	0	C22orf15	chromosome 22 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:15558]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000169327	0	0	0	0	0	0	0	0	0	0	0	0	OR5AU1	olfactory receptor family 5 subfamily AU member 1 [Source:HGNC Symbol;Acc:HGNC:15362]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000169330	1.783	1.678	1.947	1.66	1.719	2.232	246	224	197	168	200	225	MINAR1	membrane integral NOTCH2 associated receptor 1 [Source:HGNC Symbol;Acc:HGNC:29172]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0010977//negative regulation of neuron projection development;GO:0016525//negative regulation of angiogenesis;GO:0030308//negative regulation of cell growth;GO:0031397//negative regulation of protein ubiquitination;GO:0032007//negative regulation of TOR signaling	--
ENSG00000169340	0	0	0	0	0	0	0	0	0	0	0	0	PDILT	"protein disulfide isomerase like, testis expressed [Source:HGNC Symbol;Acc:HGNC:27338]"	-	-	-	-	GO:0005783//endoplasmic reticulum	GO:0003756//protein disulfide isomerase activity;GO:0016853//isomerase activity	GO:0006457//protein folding;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0016477//cell migration;GO:0030154//cell differentiation	--
ENSG00000169344	0	0	0	0	0	0	0	0	0	0	0	0	UMOD	uromodulin [Source:HGNC Symbol;Acc:HGNC:12559]	-	-	-	-	GO:0000922//spindle pole;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019864//IgG binding	GO:0001822//kidney development;GO:0002251//organ or tissue specific immune response;GO:0003091//renal water homeostasis;GO:0003094//glomerular filtration;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0006883//cellular sodium ion homeostasis;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0006986//response to unfolded protein;GO:0007029//endoplasmic reticulum organization;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0008217//regulation of blood pressure;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0009410//response to xenobiotic stimulus;GO:0009414//response to water deprivation;GO:0010467//gene expression;GO:0015747//urate transport;GO:0018107//peptidyl-threonine phosphorylation;GO:0030104//water homeostasis;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030643//cellular phosphate ion homeostasis;GO:0030644//cellular chloride ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0033555//multicellular organismal response to stress;GO:0034620//cellular response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0035809//regulation of urine volume;GO:0044861//protein transport into plasma membrane raft;GO:0046720//citric acid secretion;GO:0048871//multicellular organismal homeostasis;GO:0048878//chemical homeostasis;GO:0050801//ion homeostasis;GO:0050829//defense response to Gram-negative bacterium;GO:0051223//regulation of protein transport;GO:0055062//phosphate ion homeostasis;GO:0055064//chloride ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0060073//micturition;GO:0061077//chaperone-mediated protein folding;GO:0070294//renal sodium ion absorption;GO:0071918//urea transmembrane transport;GO:0072044//collecting duct development;GO:0072051//juxtaglomerular apparatus development;GO:0072070//loop of Henle development;GO:0072218//metanephric ascending thin limb development;GO:0072221//metanephric distal convoluted tubule development;GO:0072233//metanephric thick ascending limb development;GO:0072665//protein localization to vacuole;GO:0097190//apoptotic signaling pathway;GO:0097273//creatinine homeostasis;GO:0097709//connective tissue replacement;GO:0097744//urate salt excretion;GO:1990266//neutrophil migration	--
ENSG00000169347	0	0	0	0	0.017	0	0	0	0	0	1	0	GP2	glycoprotein 2 [Source:HGNC Symbol;Acc:HGNC:4441]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0042589//zymogen granule membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0003823//antigen binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0002376//immune system process;GO:0002412//antigen transcytosis by M cells in mucosal-associated lymphoid tissue;GO:0045087//innate immune response;GO:1990266//neutrophil migration	--
ENSG00000169359	20.313	18.822	21.487	17.149	19.952	21.806	1430	1330	1118.18	866	1102	1141	SLC33A1	solute carrier family 33 member 1 [Source:HGNC Symbol;Acc:HGNC:95]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03372;K03372	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008521//acetyl-CoA transmembrane transporter activity;GO:0015295//solute:proton symporter activity	GO:0015876//acetyl-CoA transport;GO:0030509//BMP signaling pathway;GO:0055085//transmembrane transport;GO:0060395//SMAD protein signal transduction;GO:1902600//proton transmembrane transport	--
ENSG00000169371	12.24	14.386	15.621	13.329	14.605	14.366	343	411	318	261	313	288	SNUPN	snurportin 1 [Source:HGNC Symbol;Acc:HGNC:14245]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K13151	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042564//NLS-dependent protein nuclear import complex	GO:0000339//RNA cap binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0061608//nuclear import signal receptor activity	GO:0006404//RNA import into nucleus;GO:0006606//protein import into nucleus;GO:0061015//snRNA import into nucleus	--
ENSG00000169372	5.627	5.481	5.341	6.016	5.511	7.008	138	134	97	110	115	121	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain [Source:HGNC Symbol;Acc:HGNC:2340]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1905369//endopeptidase complex	GO:0002020//protease binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0070513//death domain binding	"GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007165//signal transduction;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000169375	12.957	12.295	14.068	9.429	12.023	12.047	1264	1304	927	779	965	836	SIN3A	SIN3 transcription regulator family member A [Source:HGNC Symbol;Acc:HGNC:19353]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Endocrine system	ko05016//Huntington disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04919//Thyroid hormone signaling pathway	K11644;K11644;K11644;K11644	GO:0000118//histone deacetylase complex;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0016580//Sin3 complex;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006476//protein deacetylation;GO:0007568//aging;GO:0010243//response to organonitrogen compound;GO:0010817//regulation of hormone levels;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016575//histone deacetylation;GO:0021895//cerebral cortex neuron differentiation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030516//regulation of axon extension;GO:0031453//positive regulation of heterochromatin assembly;GO:0034613//cellular protein localization;GO:0042754//negative regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045666//positive regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051595//response to methylglyoxal;GO:0071333//cellular response to glucose stimulus;GO:1900181//negative regulation of protein localization to nucleus;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:1903351//cellular response to dopamine;GO:2000678//negative regulation of transcription regulatory region DNA binding"	--
ENSG00000169379	4.38	3.853	3.278	2.706	3.405	2.938	291	243	176	144	183	149	ARL13B	ADP ribosylation factor like GTPase 13B [Source:HGNC Symbol;Acc:HGNC:25419]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0001947//heart looping;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0009953//dorsal/ventral pattern formation;GO:0010226//response to lithium ion;GO:0021532//neural tube patterning;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0021943//formation of radial glial scaffolds;GO:0060271//cilium assembly;GO:0070986//left/right axis specification;GO:0097500//receptor localization to non-motile cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000169385	0	0	0	0	0	0	0	0	0	0	0	0	RNASE2	ribonuclease A family member 2 [Source:HGNC Symbol;Acc:HGNC:10045]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004522//ribonuclease A activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016829//lyase activity	"GO:0002227//innate immune response in mucosa;GO:0006401//RNA catabolic process;GO:0006935//chemotaxis;GO:0016070//RNA metabolic process;GO:0051607//defense response to virus;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000169393	0	0	0	0	0	0	0	0	0	0	0	0	ELSPBP1	epididymal sperm binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14417]	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0008201//heparin binding	GO:0007338//single fertilization;GO:0048240//sperm capacitation	--
ENSG00000169397	0	0	0	0	0	0	0	0	0	0	0	0	RNASE3	ribonuclease A family member 3 [Source:HGNC Symbol;Acc:HGNC:10046]	Human Diseases	Immune disease	ko05310//Asthma	K10787	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen	GO:0001530//lipopolysaccharide binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity	GO:0002227//innate immune response in mucosa;GO:0006401//RNA catabolic process;GO:0006935//chemotaxis;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000169398	36.045	33.444	34.891	29.06	28.041	31.707	2740	2478	1915	1491	1749	1647	PTK2	protein tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:9611]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Cell motility;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Immune system;Development and regeneration;Infectious disease: parasitic;Cardiovascular disease;Endocrine system;Immune system;Drug resistance: antineoplastic;Cancer: specific types;Signal transduction;Infectious disease: bacterial;Signal transduction	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko05146//Amoebiasis;ko05418//Fluid shear stress and atherosclerosis;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko01522//Endocrine resistance;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko04370//VEGF signaling pathway"	K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725;K05725	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008432//JUN kinase binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042169//SH2 domain binding	GO:0001525//angiogenesis;GO:0001890//placenta development;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0003007//heart morphogenesis;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007172//signal complex assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007411//axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010594//regulation of endothelial cell migration;GO:0010632//regulation of epithelial cell migration;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010763//positive regulation of fibroblast migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0022408//negative regulation of cell-cell adhesion;GO:0030010//establishment of cell polarity;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0035995//detection of muscle stretch;GO:0038007//netrin-activated signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045667//regulation of osteoblast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048870//cell motility;GO:0050896//response to stimulus;GO:0051128//regulation of cellular component organization;GO:0051239//regulation of multicellular organismal process;GO:0051493//regulation of cytoskeleton organization;GO:0051893//regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0060396//growth hormone receptor signaling pathway;GO:0065008//regulation of biological quality;GO:0090303//positive regulation of wound healing;GO:0120041//positive regulation of macrophage proliferation;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:1902531//regulation of intracellular signal transduction;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000811//negative regulation of anoikis	--
ENSG00000169402	0.019	0.023	0.054	0	0.098	0	1.15	1.4	2.44	0	5	0	RSPH10B2	radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385]	-	-	-	-	-	-	-	--
ENSG00000169403	0.048	0.024	0.131	0.082	0.087	0.066	4	2	8	5	5	4	PTAFR	platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signal transduction;Infectious disease: bacterial	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05150//Staphylococcus aureus infection	K04279;K04279;K04279	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070821//tertiary granule membrane	GO:0001530//lipopolysaccharide binding;GO:0001875//lipopolysaccharide immune receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004992//platelet activating factor receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0045028//G protein-coupled purinergic nucleotide receptor activity;GO:0051019//mitogen-activated protein kinase binding	GO:0002693//positive regulation of cellular extravasation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007567//parturition;GO:0009609//response to symbiotic bacterium;GO:0010863//positive regulation of phospholipase C activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032959//inositol trisphosphate biosynthetic process;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0043315//positive regulation of neutrophil degranulation;GO:0045056//transcytosis;GO:0045727//positive regulation of translation;GO:0045776//negative regulation of blood pressure;GO:0045987//positive regulation of smooth muscle contraction;GO:0046683//response to organophosphorus;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0071258//cellular response to gravity;GO:0071320//cellular response to cAMP;GO:0071398//cellular response to fatty acid;GO:0071548//response to dexamethasone;GO:1902943//positive regulation of voltage-gated chloride channel activity;GO:1903039//positive regulation of leukocyte cell-cell adhesion;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:1904058//positive regulation of sensory perception of pain;GO:1904300//positive regulation of transcytosis;GO:1904303//positive regulation of maternal process involved in parturition;GO:1904306//positive regulation of gastro-intestinal system smooth muscle contraction;GO:1904316//response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine;GO:1904317//cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	--
ENSG00000169410	5.677	6.226	6.345	6.451	6.566	6.331	923	981	762	777	902	749	PTPN9	protein tyrosine phosphatase non-receptor type 9 [Source:HGNC Symbol;Acc:HGNC:9661]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0044306//neuron projection terminus	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0010977//negative regulation of neuron projection development;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000169413	0.571	0.17	0.232	0.154	0.135	0.236	10	3	3	2	2	3	RNASE6	ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity	GO:0006401//RNA catabolic process;GO:0006952//defense response;GO:0016070//RNA metabolic process;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051607//defense response to virus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis	--
ENSG00000169418	0	0.023	0	0.016	0	0.016	0	2	0	1	0	1	NPR1	natriuretic peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:7943]	Metabolism;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Environmental adaptation;Signal transduction;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Endocrine system;Endocrine system	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04925//Aldosterone synthesis and secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K12323;K12323;K12323;K12323;K12323;K12323;K12323;K12323;K12323;K12323	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:1990620//ANPR-A receptor complex	GO:0000166//nucleotide binding;GO:0001653//peptide receptor activity;GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0016941//natriuretic peptide receptor activity;GO:0017046//peptide hormone binding;GO:0042562//hormone binding	GO:0006182//cGMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007589//body fluid secretion;GO:0008217//regulation of blood pressure;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0016525//negative regulation of angiogenesis;GO:0019934//cGMP-mediated signaling;GO:0030308//negative regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0035810//positive regulation of urine volume;GO:0035815//positive regulation of renal sodium excretion;GO:0042417//dopamine metabolic process;GO:0043114//regulation of vascular permeability;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0097746//blood vessel diameter maintenance	--
ENSG00000169427	0	0	0.052	0	0	0.032	0	0	1	0	0	1	KCNK9	potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283]	Organismal Systems	Endocrine system	ko04925//Aldosterone synthesis and secretion	K04919	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000169429	0.147	0.175	0	0	0	0	5	6	0	0	0	0	CXCL8	C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Signaling molecules and interaction;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: viral;Immune disease;Cell growth and death;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Endocrine and metabolic disease;Signaling molecules and interaction;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: parasitic;Cancer: specific types	ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko05133//Pertussis;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05134//Legionellosis;ko05144//Malaria;ko05219//Bladder cancer	K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030;K10030	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005153//interleukin-8 receptor binding;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0045236//CXCR chemokine receptor binding	GO:0001525//angiogenesis;GO:0002237//response to molecule of bacterial origin;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0009605//response to external stimulus;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0019722//calcium-mediated signaling;GO:0030155//regulation of cell adhesion;GO:0030593//neutrophil chemotaxis;GO:0031328//positive regulation of cellular biosynthetic process;GO:0031623//receptor internalization;GO:0034976//response to endoplasmic reticulum stress;GO:0035556//intracellular signal transduction;GO:0042119//neutrophil activation;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045091//regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0048566//embryonic digestive tract development;GO:0050930//induction of positive chemotaxis;GO:0060354//negative regulation of cell adhesion molecule production;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090023//positive regulation of neutrophil chemotaxis;GO:2000535//regulation of entry of bacterium into host cell	--
ENSG00000169432	0.572	0.297	0.391	0.304	0.197	0.164	52	35	22	13	18	16	SCN9A	sodium voltage-gated channel alpha subunit 9 [Source:HGNC Symbol;Acc:HGNC:10597]	Organismal Systems	Sensory system	ko04742//Taste transduction	K04841	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0031402//sodium ion binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006954//inflammatory response;GO:0009408//response to heat;GO:0009409//response to cold;GO:0009636//response to toxic substance;GO:0009791//post-embryonic development;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0045759//negative regulation of action potential;GO:0048266//behavioral response to pain;GO:0055085//transmembrane transport;GO:0061368//behavioral response to formalin induced pain;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000169435	0.751	0.316	0.226	0.184	0.223	0.245	54	30	16	16	23	18	RASSF6	Ras association domain family member 6 [Source:HGNC Symbol;Acc:HGNC:20796]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K09854;K09854	-	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0042981//regulation of apoptotic process	--
ENSG00000169436	0.655	0.97	0.533	0.42	0.348	0.669	60	59	29	19	39	21	COL22A1	collagen type XXII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22989]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K16630	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent	GO:0001525//angiogenesis;GO:0001886//endothelial cell morphogenesis;GO:0030198//extracellular matrix organization	--
ENSG00000169439	121.593	120.064	132.186	98.585	99.713	114.625	5832	5713	4320	3713	4139	3898	SDC2	syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases	Cancer: overview;Signaling molecules and interaction;Cardiovascular disease;Infectious disease: parasitic	ko05205//Proteoglycans in cancer;ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko05144//Malaria	K16336;K16336;K16336;K16336	GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:0008150//biological_process;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0048813//dendrite morphogenesis;GO:0048814//regulation of dendrite morphogenesis	--
ENSG00000169442	0	0	0	0	0.122	0	0	0	0	0	1	0	CD52	CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0097225//sperm midpiece	-	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045730//respiratory burst	--
ENSG00000169446	11.511	10.62	8.775	6.666	10.268	9.696	676	596	401	371	465	386	MMGT1	membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031901//early endosome membrane;GO:0072546//EMC complex	GO:0005515//protein binding;GO:0015087//cobalt ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0032977//membrane insertase activity	GO:0006812//cation transport;GO:0006824//cobalt ion transport;GO:0006825//copper ion transport;GO:0006826//iron ion transport;GO:0015693//magnesium ion transport;GO:0034755//iron ion transmembrane transport;GO:0045050//protein insertion into ER membrane by stop-transfer membrane-anchor sequence;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000169469	0	0	0	0	0	0	0	0	0	0	0	0	SPRR1B	small proline rich protein 1B [Source:HGNC Symbol;Acc:HGNC:11260]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005198//structural molecule activity	GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000169474	0	0	0	0	0	0	0	0	0	0	0	0	SPRR1A	small proline rich protein 1A [Source:HGNC Symbol;Acc:HGNC:11259]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000169484	0	0	0	0	0	0	0	0	0	0	0	0	OR4K14	olfactory receptor family 4 subfamily K member 14 [Source:HGNC Symbol;Acc:HGNC:15352]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000169488	0	0	0	0	0	0	0	0	0	0	0	0	OR4K15	olfactory receptor family 4 subfamily K member 15 [Source:HGNC Symbol;Acc:HGNC:15353]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000169490	32.452	30.898	29.822	31.368	29.536	33.937	1704	1643	1130	1294	1392	1319	TM2D2	TM2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24127]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000169495	3.25	4.225	2.698	3.684	5.982	4.761	137	179	84	115	213	146	HTRA4	HtrA serine peptidase 4 [Source:HGNC Symbol;Acc:HGNC:26909]	-	-	-	-	GO:0005576//extracellular region	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0012501//programmed cell death;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043065//positive regulation of apoptotic process	--
ENSG00000169499	33.467	36.034	37.651	34.667	35.421	37.157	2988	3084	2110	2177	2583	2133	PLEKHA2	pleckstrin homology domain containing A2 [Source:HGNC Symbol;Acc:HGNC:14336]	-	-	-	-	-	"GO:0030165//PDZ domain binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding"	-	--
ENSG00000169504	91.572	74.814	86.253	81.281	80.288	107.098	7839	6467	5424	5234	5719	6735	CLIC4	chloride intracellular channel 4 [Source:HGNC Symbol;Acc:HGNC:13518]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016363//nuclear matrix;GO:0030054//cell junction;GO:0030496//midbody;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034707//chloride channel complex;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001886//endothelial cell morphogenesis;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007035//vacuolar acidification;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0030216//keratinocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0035264//multicellular organism growth;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051493//regulation of cytoskeleton organization;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0071277//cellular response to calcium ion	--
ENSG00000169507	0.811	0.724	0.805	1.444	0.66	1.391	58	40	33	56	42	55	SLC38A11	solute carrier family 38 member 11 [Source:HGNC Symbol;Acc:HGNC:26836]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport	--
ENSG00000169508	0	0	0	0	0	0	0	0	0	0	0	0	GPR183	G protein-coupled receptor 183 [Source:HGNC Symbol;Acc:HGNC:3128]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008142//oxysterol binding	GO:0002250//adaptive immune response;GO:0002312//B cell activation involved in immune response;GO:0002313//mature B cell differentiation involved in immune response;GO:0002376//immune system process;GO:0002407//dendritic cell chemotaxis;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010818//T cell chemotaxis;GO:0030316//osteoclast differentiation;GO:0030595//leukocyte chemotaxis;GO:0030890//positive regulation of B cell proliferation;GO:0036145//dendritic cell homeostasis;GO:0060326//cell chemotaxis;GO:0061470//T follicular helper cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000458//regulation of astrocyte chemotaxis	--
ENSG00000169509	0	0	0	0	0	0	0	0	0	0	0	0	CRCT1	cysteine rich C-terminal 1 [Source:HGNC Symbol;Acc:HGNC:29875]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000169515	10.399	9.916	9.804	10.036	9.805	9.132	698	669	486	499	556	446	CCDC8	coiled-coil domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25367]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:1990393//3M complex	GO:0005515//protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0007088//regulation of mitotic nuclear division	--
ENSG00000169519	3.251	2.295	2.076	2.116	2.299	3.135	255	201	134	129	149	184	METTL15	methyltransferase like 15 [Source:HGNC Symbol;Acc:HGNC:26606]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0071424//rRNA (cytosine-N4-)-methyltransferase activity	GO:0032259//methylation;GO:0070475//rRNA base methylation	--
ENSG00000169548	0	0	0	0	0	0	0	0	0	0	0	0	ZNF280A	zinc finger protein 280A [Source:HGNC Symbol;Acc:HGNC:18597]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Others
ENSG00000169550	0.016	0.15	0.044	0.083	0.091	0.039	1	9	2	4	3	2	MUC15	"mucin 15, cell surface associated [Source:HGNC Symbol;Acc:HGNC:14956]"	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000169551	0	0	0	0	0	0.046	0	0	0	0	0	1	CT55	cancer/testis antigen 55 [Source:HGNC Symbol;Acc:HGNC:26047]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000169554	17.259	16.168	15.093	13.403	15.372	17.678	1768	1416	985	894	1109	1025	ZEB2	zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881]	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K23560	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043226//organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0045636//positive regulation of melanocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048023//positive regulation of melanin biosynthetic process;GO:0048066//developmental pigmentation;GO:0048856//anatomical structure development;GO:0050790//regulation of catalytic activity;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097324//melanocyte migration;GO:1903056//regulation of melanosome organization"	zf-C2H2
ENSG00000169562	2.387	2.626	1.711	4.821	3.474	4.091	85	94	45	128	104	106	GJB1	gap junction protein beta 1 [Source:HGNC Symbol;Acc:HGNC:4283]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex	GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0015868//purine ribonucleotide transport;GO:0016264//gap junction assembly;GO:0055085//transmembrane transport;GO:1905867//epididymis development	--
ENSG00000169564	159.346	165.808	177.575	157.043	161.843	166.706	5708	5970	4698	4167	4898	4345	PCBP1	poly(rC) binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8647]	Genetic Information Processing;Cellular Processes	Transcription;Cell growth and death	ko03040//Spliceosome;ko04216//Ferroptosis	K12889;K12889	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0098847//sequence-specific single stranded DNA binding"	GO:0010468//regulation of gene expression;GO:0039694//viral RNA genome replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051252//regulation of RNA metabolic process	--
ENSG00000169567	93.528	92.269	88.158	108.423	85.927	101.773	1742	1712	1206	1484	1357	1372	HINT1	histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0043530//adenosine 5'-monophosphoramidase activity;GO:0070140//SUMO-specific isopeptidase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0016926//protein desumoylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator"	--
ENSG00000169570	4.166	3.104	2.215	2.254	3.392	4.657	415	320	196	200	240	261	DTWD2	DTW domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19334]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0016432//tRNA-uridine aminocarboxypropyltransferase activity;GO:0016740//transferase activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing	--
ENSG00000169575	0	0	0	0	0	0	0	0	0	0	0	0	VPREB1	V-set pre-B cell surrogate light chain 1 [Source:HGNC Symbol;Acc:HGNC:12709]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	-	GO:0006955//immune response	--
ENSG00000169583	4.052	2.846	3.066	1.126	1.552	1.72	68	48	38	14	22	21	CLIC3	chloride intracellular channel 3 [Source:HGNC Symbol;Acc:HGNC:2064]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0034707//chloride channel complex;GO:0070062//extracellular exosome	GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding	GO:0006749//glutathione metabolic process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport	--
ENSG00000169592	18.755	17.211	19.716	19.27	19.24	18.915	292.95	305	220	239.99	264.98	257	INO80E	INO80 complex subunit E [Source:HGNC Symbol;Acc:HGNC:26905]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031011//Ino80 complex	GO:0005515//protein binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	--
ENSG00000169594	24.18	19.874	23.387	23.944	22.373	30.238	2303	1902	1643	1685	1797	2092	BNC1	basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0000182//rDNA binding;GO:0001216//DNA-binding transcription activator activity;GO:0003677//DNA binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006356//regulation of transcription by RNA polymerase I;GO:0007283//spermatogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0008544//epidermis development;GO:0030154//cell differentiation;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:1900195//positive regulation of oocyte maturation"	zf-C2H2
ENSG00000169598	0.993	1.887	2.068	1.383	1.577	1.218	57	94	82	62	79	49	DFFB	DNA fragmentation factor subunit beta [Source:HGNC Symbol;Acc:HGNC:2773]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K02311	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004536//deoxyribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0097718//disordered domain specific binding	GO:0006308//DNA catabolic process;GO:0006309//apoptotic DNA fragmentation;GO:0006915//apoptotic process;GO:0030263//apoptotic chromosome condensation	--
ENSG00000169599	19.587	17.481	17.69	20.119	15.59	20.374	364	323	237	274	237	270	NFU1	NFU1 iron-sulfur cluster scaffold [Source:HGNC Symbol;Acc:HGNC:16287]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000169604	60.029	65.431	44.975	50.467	56.467	44.238	6298	6693	3597	3691	4796	3376	ANTXR1	ANTXR cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:21014]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20909	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031258//lamellipodium membrane;GO:0031527//filopodium membrane;GO:0042995//cell projection	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0001568//blood vessel development;GO:0022414//reproductive process;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:1901202//negative regulation of extracellular matrix assembly;GO:1901998//toxin transport;GO:1905050//positive regulation of metallopeptidase activity	--
ENSG00000169605	0	0	0	0	0.076	0	0	0	0	0	1	0	GKN1	gastrokine 1 [Source:HGNC Symbol;Acc:HGNC:23217]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007586//digestion;GO:0042127//regulation of cell population proliferation;GO:0051781//positive regulation of cell division	--
ENSG00000169607	0.146	0.122	0.263	0.141	0.109	0.14	12	12	19	10	9	10	CKAP2L	cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0072686//mitotic spindle	-	-	--
ENSG00000169609	2.488	4.213	4.264	9.61	3.972	6.759	251.43	208.22	172.5	188.5	214.24	139.5	C15orf40	chromosome 15 open reading frame 40 [Source:HGNC Symbol;Acc:HGNC:28443]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000169612	15.187	13.516	13.806	13.599	12.653	15.581	493	441	331	327	347	368	RAMAC	RNA guanine-7 methyltransferase activating subunit [Source:HGNC Symbol;Acc:HGNC:31022]	-	-	-	-	GO:0005634//nucleus;GO:0005845//mRNA cap binding complex;GO:0031533//mRNA cap methyltransferase complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0032259//methylation;GO:0036031//recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex;GO:0050790//regulation of catalytic activity;GO:0106005//RNA 5'-cap (guanine-N7)-methylation	--
ENSG00000169618	0	0	0	0	0	0	0	0	0	0	0	0	PROKR1	prokineticin receptor 1 [Source:HGNC Symbol;Acc:HGNC:4524]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000169621	0.391	0.301	0.546	0.221	0.254	0.118	27	24	32	13	17	6	APLF	aprataxin and PNKP like factor [Source:HGNC Symbol;Acc:HGNC:28724]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0035861//site of double-strand break	GO:0000166//nucleotide binding;GO:0003906//DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000012//single strand break repair;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0007186//G protein-coupled receptor signaling pathway;GO:0045191//regulation of isotype switching;GO:0051106//positive regulation of DNA ligation;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000169627	3.441	1.43	1.918	4.987	3.544	1.386	39.85	28.21	28.11	48.5	28.55	20.75	BOLA2B	bolA family member 2B [Source:HGNC Symbol;Acc:HGNC:32479]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990229//iron-sulfur cluster assembly complex	"GO:0005515//protein binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006879//cellular iron ion homeostasis;GO:0016226//iron-sulfur cluster assembly;GO:0044571//[2Fe-2S] cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000169629	1.686	1.735	1.859	1.229	1.284	1.792	251.54	264.08	200.64	137.78	164.28	197.37	RGPD8	RANBP2 like and GRIP domain containing 8 [Source:HGNC Symbol;Acc:HGNC:9849]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0008150//biological_process;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000169635	1.042	0.646	0.802	1.153	1.044	0.941	147	92	81	121	125	97	HIC2	HIC ZBTB transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:18595]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	ZBTB
ENSG00000169641	6.661	7.396	5.748	4.978	6.152	5.272	1014	967	641	529	681	582	LUZP1	leucine zipper protein 1 [Source:HGNC Symbol;Acc:HGNC:14985]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0070062//extracellular exosome	-	GO:0003281//ventricular septum development;GO:0021503//neural fold bending;GO:0060840//artery development	--
ENSG00000169660	4.62	5.163	6.736	7.569	5.734	7.208	192	195	207	197.53	198	211.26	HEXD	hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00513//Various types of N-glycan biosynthesis;ko00511//Other glycan degradation	K14459;K14459;K14459	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1903561//extracellular vesicle	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0015929//hexosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0102148//N-acetyl-beta-D-galactosaminidase activity"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000169676	0	0	0	0	0	0	0	0	0	0	0	0	DRD5	dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04728//Dopaminergic synapse	K05840;K05840;K05840;K05840	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0045202//synapse;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	"GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs;GO:0004930//G protein-coupled receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0005515//protein binding;GO:0035240//dopamine binding"	"GO:0001963//synaptic transmission, dopaminergic;GO:0001975//response to amphetamine;GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0001994//norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007617//mating behavior;GO:0008306//associative learning;GO:0019226//transmission of nerve impulse;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0042060//wound healing;GO:0042220//response to cocaine;GO:0045762//positive regulation of adenylate cyclase activity;GO:0045776//negative regulation of blood pressure;GO:0045924//regulation of female receptivity;GO:0046960//sensitization;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0060292//long-term synaptic depression;GO:0071870//cellular response to catecholamine stimulus;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0072593//reactive oxygen species metabolic process"	--
ENSG00000169679	1.015	1.561	0.867	0.623	0.664	0.634	78	90	46	36	42	21	BUB1	BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148]	Cellular Processes;Cellular Processes;Organismal Systems	Cell growth and death;Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K02178;K02178;K02178	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007063//regulation of sister chromatid cohesion;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0051301//cell division;GO:0051754//meiotic sister chromatid cohesion, centromeric;GO:0051983//regulation of chromosome segregation"	--
ENSG00000169682	42.936	45.475	47.78	55.143	52.415	51.686	1894	2013	1564	1821	1937	1677	SPNS1	sphingolipid transporter 1 (putative) [Source:HGNC Symbol;Acc:HGNC:30621]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006869//lipid transport;GO:0055085//transmembrane transport	--
ENSG00000169683	3.866	3.911	4.5	4.67	4.336	4.666	206	220	186	168	205	190	LRRC45	leucine rich repeat containing 45 [Source:HGNC Symbol;Acc:HGNC:28302]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	GO:0005515//protein binding	-	--
ENSG00000169684	13.839	12.098	14.432	9.532	9.403	11.915	1040	840	635	470	597	604	CHRNA5	cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04807	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098691//dopaminergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	"GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0035095//behavioral response to nicotine;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000169688	0	0	0	0	0	0	0	0	0	0	0	0	MT1B	metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000169689	8.054	8.095	9.295	8.132	8.787	9.112	125	128	107	94	116	103	CENPX	centromere protein X [Source:HGNC Symbol;Acc:HGNC:11422]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15360	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex"	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding	GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031297//replication fork processing;GO:0031398//positive regulation of protein ubiquitination;GO:0036297//interstrand cross-link repair;GO:0051301//cell division;GO:0051382//kinetochore assembly	Others
ENSG00000169692	26.374	26.496	22.924	25.67	23.879	25.72	841	852	541	601	644	597	AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:325]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K13509;K13509;K13509;K13509;K13509	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0001819//positive regulation of cytokine production;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008544//epidermis development;GO:0008654//phospholipid biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0016024//CDP-diacylglycerol biosynthetic process	--
ENSG00000169696	13.232	12.529	11.553	15.386	13.259	11.872	458	452	307	409	411	284	ASPSCR1	"ASPSCR1 tether for SLC2A4, UBX domain containing [Source:HGNC Symbol;Acc:HGNC:13825]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15627	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0012505//endomembrane system;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0031401//positive regulation of protein modification process;GO:0042593//glucose homeostasis;GO:0046324//regulation of glucose import	--
ENSG00000169704	0	0	0	0	0	0	0	0	0	0	0	0	GP9	glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444]	Organismal Systems;Organismal Systems;Environmental Information Processing	Immune system;Immune system;Signaling molecules and interaction	ko04640//Hematopoietic cell lineage;ko04611//Platelet activation;ko04512//ECM-receptor interaction	K06263;K06263;K06263	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990779//glycoprotein Ib-IX-V complex	GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis;GO:0010572//positive regulation of platelet activation;GO:0035855//megakaryocyte development;GO:0051209//release of sequestered calcium ion into cytosol"	--
ENSG00000169710	56.675	54.375	65.715	70.117	68.389	77.267	9040	9027	7713	7837	9314	8415	FASN	fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Signal transduction;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis	K00665;K00665;K00665;K00665;K00665;K00665	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042470//melanosome;GO:0042587//glycogen granule;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004312//fatty acid synthase activity;GO:0004313//[acyl-carrier-protein] S-acetyltransferase activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0004317//3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0005515//protein binding;GO:0008659//(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity;GO:0008693//3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity;GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0016297//acyl-[acyl-carrier-protein] hydrolase activity;GO:0016418//S-acetyltransferase activity;GO:0016419//S-malonyltransferase activity;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0019171//3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity;GO:0031177//phosphopantetheine binding;GO:0045296//cadherin binding;GO:0047117//enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity;GO:0047451//3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"	GO:0001649//osteoblast differentiation;GO:0002068//glandular epithelial cell development;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0008611//ether lipid biosynthetic process;GO:0009058//biosynthetic process;GO:0009888//tissue development;GO:0030223//neutrophil differentiation;GO:0030224//monocyte differentiation;GO:0030879//mammary gland development;GO:0071353//cellular response to interleukin-4;GO:0090557//establishment of endothelial intestinal barrier	--
ENSG00000169714	122.319	118.456	123.456	113.092	109.193	133.334	4233	4102	3155	2888	3208	3333	CNBP	CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0045182//translation regulator activity;GO:0046872//metal ion binding;GO:0051880//G-quadruplex DNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0042632//cholesterol homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071919//G-quadruplex DNA formation;GO:2000767//positive regulation of cytoplasmic translation"	Others
ENSG00000169715	5.402	5.042	5.002	10.067	9.569	9.873	79	74	54	109	110	105	MT1E	metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000169717	0	0	0	0	0	0	0	0	0	0	0	0	ACTRT2	actin related protein T2 [Source:HGNC Symbol;Acc:HGNC:24026]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	-	-	--
ENSG00000169718	14.385	14.391	14.906	18.793	17.408	18.434	525	571	395	493	547	497	DUS1L	dihydrouridine synthase 1 like [Source:HGNC Symbol;Acc:HGNC:30086]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0002943//tRNA dihydrouridine synthesis;GO:0008033//tRNA processing	--
ENSG00000169727	50.509	55.393	58.791	65.723	59.421	58.213	1856	1901	1549	1706.89	1792	1468	GPS1	G protein pathway suppressor 1 [Source:HGNC Symbol;Acc:HGNC:4549]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex	GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding	GO:0000338//protein deneddylation;GO:0007254//JNK cascade;GO:0043086//negative regulation of catalytic activity;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000169733	11.427	16.477	12.598	15.3	15.015	14.77	400	556	332	429.11	442	374	RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:9974]	Human Diseases;Environmental Information Processing;Metabolism	Infectious disease: viral;Signal transduction;Glycan biosynthesis and metabolism	ko05165//Human papillomavirus infection;ko04330//Notch signaling pathway;ko00514//Other types of O-glycan biosynthesis	K05948;K05948;K05948	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0003674//molecular_function;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding	GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0008593//regulation of Notch signaling pathway;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0032092//positive regulation of protein binding;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000169738	15.192	15.76	16.209	22.273	17.414	20.538	265	270	210	283	260	256	DCXR	dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00040//Pentose and glucuronate interconversions	K03331;K03331	GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0004090//carbonyl reductase (NADPH) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0042802//identical protein binding;GO:0050038//L-xylulose reductase (NADP+) activity"	GO:0005975//carbohydrate metabolic process;GO:0005997//xylulose metabolic process;GO:0006006//glucose metabolic process;GO:0006739//NADP metabolic process;GO:0042732//D-xylose metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000169740	21.322	20.312	22.022	19.773	18.88	19.952	513	493	391	353	384	349	ZNF32	zinc finger protein 32 [Source:HGNC Symbol;Acc:HGNC:13095]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000169744	0.136	0.297	0.309	0.778	1.634	0.953	7	10	12	27	57	33	LDB2	LIM domain binding 2 [Source:HGNC Symbol;Acc:HGNC:6533]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0031252//cell leading edge	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030274//LIM domain binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001942//hair follicle development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0010669//epithelial structure maintenance;GO:0030334//regulation of cell migration;GO:0035019//somatic stem cell population maintenance;GO:0043549//regulation of kinase activity;GO:0044089//positive regulation of cellular component biogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000169750	9.708	11.343	14.238	14.776	13.491	16.72	203	238	220	232	241	261	RAC3	Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Immune system;Development and regeneration;Signal transduction;Immune system;Cardiovascular disease;Immune system;Cardiovascular disease;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Signal transduction	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04310//Wnt signaling pathway;ko04662//B cell receptor signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko04071//Sphingolipid signaling pathway;ko05231//Choline metabolism in cancer;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko04520//Adherens junction;ko04370//VEGF signaling pathway	K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861;K07861	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0031941//filamentous actin;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043020//NADPH oxidase complex;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0048306//calcium-dependent protein binding	"GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0014041//regulation of neuron maturation;GO:0016055//Wnt signaling pathway;GO:0021894//cerebral cortex GABAergic interneuron development;GO:0022604//regulation of cell morphogenesis;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030865//cortical cytoskeleton organization;GO:0031175//neuron projection development;GO:0032956//regulation of actin cytoskeleton organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035556//intracellular signal transduction;GO:0045730//respiratory burst;GO:0048873//homeostasis of number of cells within a tissue;GO:0050885//neuromuscular process controlling balance;GO:0050905//neuromuscular process;GO:0051932//synaptic transmission, GABAergic;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading"	--
ENSG00000169752	0.615	0.177	0	0.16	0.037	0	10.09	4	0	2	2.09	0	NRG4	neuregulin 4 [Source:HGNC Symbol;Acc:HGNC:29862]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko04012//ErbB signaling pathway	K05458;K05458	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007399//nervous system development	--
ENSG00000169756	13.606	12.095	10.988	9.761	10.755	9.343	989.29	841.51	590.87	476.79	587.72	510.8	LIMS1	LIM zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:6616]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding	"GO:0007569//cell aging;GO:0010628//positive regulation of gene expression;GO:0010811//positive regulation of cell-substrate adhesion;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0045184//establishment of protein localization;GO:0045216//cell-cell junction organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051894//positive regulation of focal adhesion assembly;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0098609//cell-cell adhesion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2001046//positive regulation of integrin-mediated signaling pathway"	--
ENSG00000169758	0.122	0.126	0.234	0.148	0.144	0.087	6	6	8	4	6	3	TMEM266	transmembrane protein 266 [Source:HGNC Symbol;Acc:HGNC:26763]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005515//protein binding;GO:0022832//voltage-gated channel activity;GO:0042803//protein homodimerization activity	GO:0055085//transmembrane transport	--
ENSG00000169760	0.796	0.936	0.377	1.928	1.382	1.058	131	69	37	116	103	83	NLGN1	neuroligin 1 [Source:HGNC Symbol;Acc:HGNC:14291]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07378	"GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0032433//filopodium tip;GO:0043083//synaptic cleft;GO:0043197//dendritic spine;GO:0043235//receptor complex;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0060077//inhibitory synapse;GO:0089717//spanning component of membrane;GO:0097060//synaptic membrane;GO:0098635//protein complex involved in cell-cell adhesion;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0098984//neuron to neuron synapse;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0001540//amyloid-beta binding;GO:0030165//PDZ domain binding;GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0097110//scaffold protein binding	"GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006605//protein targeting;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0010976//positive regulation of neuron projection development;GO:0016080//synaptic vesicle targeting;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0023041//neuronal signal transduction;GO:0031175//neuron projection development;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0035418//protein localization to synapse;GO:0045184//establishment of protein localization;GO:0045664//regulation of neuron differentiation;GO:0048488//synaptic vesicle endocytosis;GO:0048511//rhythmic process;GO:0048789//cytoskeletal matrix organization at active zone;GO:0048812//neuron projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0051491//positive regulation of filopodium assembly;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060074//synapse maturation;GO:0060999//positive regulation of dendritic spine development;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0071277//cellular response to calcium ion;GO:0072553//terminal button organization;GO:0090125//cell-cell adhesion involved in synapse maturation;GO:0097091//synaptic vesicle clustering;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0097113//AMPA glutamate receptor clustering;GO:0097114//NMDA glutamate receptor clustering;GO:0097115//neurexin clustering involved in presynaptic membrane assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0097120//receptor localization to synapse;GO:0098698//postsynaptic specialization assembly;GO:0099054//presynapse assembly;GO:0099558//maintenance of synapse structure;GO:0099560//synaptic membrane adhesion;GO:0140058//neuron projection arborization;GO:1900029//positive regulation of ruffle assembly;GO:1900075//positive regulation of neuromuscular synaptic transmission;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:1902533//positive regulation of intracellular signal transduction;GO:1904861//excitatory synapse assembly;GO:2000302//positive regulation of synaptic vesicle exocytosis;GO:2000310//regulation of NMDA receptor activity;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000809//positive regulation of synaptic vesicle clustering"	--
ENSG00000169762	7.866	7.175	7.152	6.719	7.721	7.214	530	464	372	315	368	366	TAPT1	transmembrane anterior posterior transformation 1 [Source:HGNC Symbol;Acc:HGNC:26887]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0016520//growth hormone-releasing hormone receptor activity	GO:0001503//ossification;GO:0007186//G protein-coupled receptor signaling pathway;GO:0014032//neural crest cell development;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0045724//positive regulation of cilium assembly;GO:0048706//embryonic skeletal system development;GO:0048856//anatomical structure development;GO:0051216//cartilage development;GO:0061036//positive regulation of cartilage development;GO:1903012//positive regulation of bone development	--
ENSG00000169763	0	0	0	0	0	0	0	0	0	0	0	0	PRYP3	PTPN13 like Y-linked pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:34020]	-	-	-	-	-	-	-	--
ENSG00000169764	47.124	43.944	41.005	37.978	36.662	41.588	2032	1892	1294	1228	1314	1310	UGP2	UDP-glucose pyrophosphorylase 2 [Source:HGNC Symbol;Acc:HGNC:12527]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00500//Starch and sucrose metabolism;ko00040//Pentose and glucuronate interconversions;ko00052//Galactose metabolism	K00963;K00963;K00963;K00963;K00963	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003983//UTP:glucose-1-phosphate uridylyltransferase activity;GO:0005515//protein binding;GO:0005536//glucose binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0032557//pyrimidine ribonucleotide binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070569//uridylyltransferase activity	GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006011//UDP-glucose metabolic process;GO:0007420//brain development;GO:0019255//glucose 1-phosphate metabolic process	--
ENSG00000169777	0	0.016	0	0	0	0.088	0	1	0	0	0	4	TAS2R1	taste 2 receptor member 1 [Source:HGNC Symbol;Acc:HGNC:14909]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000169783	0.387	0.346	0.92	0.291	0.408	0.474	26	16	24	8	16	14	LINGO1	leucine rich repeat and Ig domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21205]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding	-	--
ENSG00000169789	0	0	0	0	0	0	0	0	0	0	0	0	PRY	PTPN13 like Y-linked [Source:HGNC Symbol;Acc:HGNC:14024]	-	-	-	-	-	-	-	--
ENSG00000169800	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1F	RNA binding motif protein Y-linked family 1 member F [Source:HGNC Symbol;Acc:HGNC:23974]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing"	--
ENSG00000169807	0	0	0	0	0	0	0	0	0	0	0	0	PRY2	PTPN13 like Y-linked 2 [Source:HGNC Symbol;Acc:HGNC:21504]	-	-	-	-	-	-	-	--
ENSG00000169813	83.969	81.162	91.398	91.578	88.103	101.918	3633	3617	2949	2896	3238	3213	HNRNPF	heterogeneous nuclear ribonucleoprotein F [Source:HGNC Symbol;Acc:HGNC:5039]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0017025//TBP-class protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing"	--
ENSG00000169814	36.503	33.806	33.118	28.958	27.596	30.753	2346	2302	1679	1302	1559	1485	BTD	biotinidase [Source:HGNC Symbol;Acc:HGNC:1122]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04977//Vitamin digestion and absorption;ko00780//Biotin metabolism	K01435;K01435;K01435	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	"GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0047708//biotinidase activity"	GO:0006768//biotin metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0007417//central nervous system development	--
ENSG00000169826	35.137	28.753	28.417	13.622	16.551	19.676	2744	2257	1639	788	1092	1118	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:24292]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00746;K00746	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	"GO:0030166//proteoglycan biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0050652//dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0050653//chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process"	--
ENSG00000169836	0	0	0	0	0	0	0	0	0	0	0	0	TACR3	tachykinin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11528]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04224;K04224	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0097225//sperm midpiece	GO:0004930//G protein-coupled receptor activity;GO:0004995//tachykinin receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007217//tachykinin receptor signaling pathway;GO:0007568//aging;GO:0010460//positive regulation of heart rate;GO:0032355//response to estradiol;GO:0042053//regulation of dopamine metabolic process;GO:0042220//response to cocaine;GO:0042538//hyperosmotic salinity response;GO:0043278//response to morphine;GO:0045777//positive regulation of blood pressure;GO:0060259//regulation of feeding behavior;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:1902093//positive regulation of flagellated sperm motility	--
ENSG00000169840	0	0	0	0	0	0	0	0	0	0	0	0	GSX1	GS homeobox 1 [Source:HGNC Symbol;Acc:HGNC:20374]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0021527//spinal cord association neuron differentiation;GO:0021854//hypothalamus development;GO:0021984//adenohypophysis development;GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048663//neuron fate commitment"	Homeobox
ENSG00000169851	32.157	29.423	24.507	17.767	19.549	19.556	5229	4608	2670	1956	2583	2215	PCDH7	protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000169855	5.301	6.053	4.498	3.755	4.262	5.214	693	648	435	344	479	476	ROBO1	roundabout guidance receptor 1 [Source:HGNC Symbol;Acc:HGNC:10249]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06753	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0030275//LRR domain binding;GO:0042802//identical protein binding	GO:0002042//cell migration involved in sprouting angiogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003272//endocardial cushion formation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016199//axon midline choice point recognition;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035385//Roundabout signaling pathway;GO:0035481//positive regulation of Notch signaling pathway involved in heart induction;GO:0035904//aorta development;GO:0043406//positive regulation of MAP kinase activity;GO:0050772//positive regulation of axonogenesis;GO:0050925//negative regulation of negative chemotaxis;GO:0060412//ventricular septum morphogenesis;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway	--
ENSG00000169856	0	0	0	0.015	0	0	0	0	0	1	0	0	ONECUT1	one cut homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8138]	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Endocrine and metabolic disease	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04950//Maturity onset diabetes of the young	K08026;K08026	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001889//liver development;GO:0001952//regulation of cell-matrix adhesion;GO:0002064//epithelial cell development;GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007492//endoderm development;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048536//spleen development;GO:0060271//cilium assembly"	CUT
ENSG00000169857	6.908	5.786	5.356	6.218	6.08	4.423	234	197	134	156	174	109	AVEN	apoptosis and caspase activation inhibitor [Source:HGNC Symbol;Acc:HGNC:13509]	-	-	-	-	GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0043066//negative regulation of apoptotic process	--
ENSG00000169860	0.267	0.243	0.259	0.268	0.262	0.273	35	32	25	26	29	26	P2RY1	purinergic receptor P2Y1 [Source:HGNC Symbol;Acc:HGNC:8539]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04015//Rap1 signaling pathway;ko04611//Platelet activation;ko04742//Taste transduction	K04270;K04270;K04270;K04270	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane	GO:0000166//nucleotide binding;GO:0001621//G protein-coupled ADP receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031686//A1 adenosine receptor binding;GO:0038023//signaling receptor activity;GO:0043531//ADP binding;GO:0045028//G protein-coupled purinergic nucleotide receptor activity;GO:0045031//G protein-coupled ATP receptor activity;GO:0046982//protein heterodimerization activity;GO:0097110//scaffold protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007568//aging;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008347//glial cell migration;GO:0008360//regulation of cell shape;GO:0009612//response to mechanical stimulus;GO:0010469//regulation of signaling receptor activity;GO:0010700//negative regulation of norepinephrine secretion;GO:0019233//sensory perception of pain;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030168//platelet activation;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0042060//wound healing;GO:0042755//eating behavior;GO:0043270//positive regulation of ion transport;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046887//positive regulation of hormone secretion;GO:0051100//negative regulation of binding;GO:0060406//positive regulation of penile erection;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070848//response to growth factor;GO:0071318//cellular response to ATP;GO:0071407//cellular response to organic cyclic compound;GO:0071415//cellular response to purine-containing compound;GO:0072659//protein localization to plasma membrane;GO:0090075//relaxation of muscle;GO:0097746//blood vessel diameter maintenance;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000169862	15.978	17.03	18.797	15.81	15.997	15.271	1614	1651	1353	1053	1301	1065	CTNND2	catenin delta 2 [Source:HGNC Symbol;Acc:HGNC:2516]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K23491	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0045296//cadherin binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0050808//synapse organization;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060997//dendritic spine morphogenesis;GO:0098609//cell-cell adhesion	--
ENSG00000169871	5.686	4.956	5.001	4.852	5.029	5.07	1286.73	1127.27	835.78	813.26	961.48	834.87	TRIM56	tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028]	-	-	-	-	GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0002376//immune system process;GO:0006513//protein monoubiquitination;GO:0032479//regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0034340//response to type I interferon;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0070534//protein K63-linked ubiquitination"	--
ENSG00000169876	0	0	0	0	0	0	0	0	0	0	0	0	MUC17	"mucin 17, cell surface associated [Source:HGNC Symbol;Acc:HGNC:16800]"	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0071944//cell periphery	"GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0030197//extracellular matrix constituent, lubricant activity"	GO:0019725//cellular homeostasis	--
ENSG00000169877	0	0	0	0	0	0	0	0	0	0	0	0	AHSP	alpha hemoglobin stabilizing protein [Source:HGNC Symbol;Acc:HGNC:18075]	-	-	-	-	GO:0005737//cytoplasm;GO:0005833//hemoglobin complex	GO:0005515//protein binding;GO:0030492//hemoglobin binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0020027//hemoglobin metabolic process;GO:0030097//hemopoiesis;GO:0030218//erythrocyte differentiation;GO:0050821//protein stabilization	--
ENSG00000169884	0	0	0	0	0	0	0	0	0	0	0	0	WNT10B	Wnt family member 10B [Source:HGNC Symbol;Acc:HGNC:12775]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357;K01357	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002062//chondrocyte differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0007224//smoothened signaling pathway;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014835//myoblast differentiation involved in skeletal muscle regeneration;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030858//positive regulation of epithelial cell differentiation;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043403//skeletal muscle tissue regeneration;GO:0045165//cell fate commitment;GO:0045598//regulation of fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045899//positive regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048641//regulation of skeletal muscle tissue development;GO:0048741//skeletal muscle fiber development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050821//protein stabilization;GO:0050909//sensory perception of taste;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051246//regulation of protein metabolic process;GO:0051726//regulation of cell cycle;GO:0051885//positive regulation of timing of anagen;GO:0060070//canonical Wnt signaling pathway;GO:0060346//bone trabecula formation;GO:0061196//fungiform papilla development;GO:0071300//cellular response to retinoic acid;GO:0071310//cellular response to organic substance;GO:0071320//cellular response to cAMP;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071425//hematopoietic stem cell proliferation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000169885	0	0	0	0	0	0	0	0	0	0	0	0	CALML6	calmodulin like 6 [Source:HGNC Symbol;Acc:HGNC:24193]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000169891	0.786	0.692	0.535	0.522	0.651	0.274	127	113	64	64	91	33	REPS2	RALBP1 associated Eps domain containing 2 [Source:HGNC Symbol;Acc:HGNC:9963]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016197//endosomal transport;GO:0065003//protein-containing complex assembly	--
ENSG00000169894	0	0	0	0	0	0	0	0	0	0	0	0	MUC3A	"mucin 3A, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7513]"	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005201//extracellular matrix structural constituent;GO:0030197//extracellular matrix constituent, lubricant activity"	-	--
ENSG00000169895	7.099	6.696	6.546	4.601	5.017	5.955	906	859	617	435	541	553	SYAP1	synapse associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16273]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0032869//cellular response to insulin stimulus;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038203//TORC2 signaling;GO:0045600//positive regulation of fat cell differentiation;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:1990314//cellular response to insulin-like growth factor stimulus	--
ENSG00000169896	0	0	0	0	0	0	0	0	0	0	0	0	ITGAM	integrin subunit alpha M [Source:HGNC Symbol;Acc:HGNC:6149]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Cell motility;Signal transduction;Transport and catabolism;Infectious disease: parasitic;Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: bacterial;Cancer: specific types;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05146//Amoebiasis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko04670//Leukocyte transendothelial migration;ko04610//Complement and coagulation cascades;ko05133//Pertussis;ko05221//Acute myeloid leukemia;ko05134//Legionellosis	K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461;K06461	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034688//integrin alphaM-beta2 complex;GO:0035579//specific granule membrane;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0001540//amyloid-beta binding;GO:0001851//complement component C3b binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0038024//cargo receptor activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	"GO:0001774//microglial cell activation;GO:0002376//immune system process;GO:0006898//receptor-mediated endocytosis;GO:0006911//phagocytosis, engulfment;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0010668//ectodermal cell differentiation;GO:0030900//forebrain development;GO:0032930//positive regulation of superoxide anion generation;GO:0033627//cell adhesion mediated by integrin;GO:0043315//positive regulation of neutrophil degranulation;GO:0045087//innate immune response;GO:0045963//negative regulation of dopamine metabolic process;GO:0090314//positive regulation of protein targeting to membrane;GO:0097190//apoptotic signaling pathway;GO:0097242//amyloid-beta clearance;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0110090//positive regulation of hippocampal neuron apoptotic process;GO:0150062//complement-mediated synapse pruning;GO:0150064//vertebrate eye-specific patterning;GO:1901216//positive regulation of neuron death;GO:1904151//positive regulation of microglial cell mediated cytotoxicity;GO:1905114//cell surface receptor signaling pathway involved in cell-cell signaling;GO:2000363//positive regulation of prostaglandin-E synthase activity"	--
ENSG00000169900	0	0	0	0	0	0	0	0	0	0	0	0	PYDC1	pyrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30261]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12802	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008385//IkappaB kinase complex	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0006508//proteolysis;GO:0009968//negative regulation of signal transduction;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032731//positive regulation of interleukin-1 beta production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045087//innate immune response	--
ENSG00000169902	8.406	8.729	7.019	5.98	5.272	7.177	333	316	213	182	183	202	TPST1	tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0008146//sulfotransferase activity;GO:0008476//protein-tyrosine sulfotransferase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	GO:0006478//peptidyl-tyrosine sulfation;GO:0006954//inflammatory response;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process	--
ENSG00000169903	0.129	0.032	0.088	0.24	0.038	0.044	4	1	2	2	1	1	TM4SF4	transmembrane 4 L six family member 4 [Source:HGNC Symbol;Acc:HGNC:11856]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0042246//tissue regeneration	--
ENSG00000169905	8.375	7.48	7.44	3.379	5.437	6.449	829	656	565	349	474	497	TOR1AIP2	torsin 1A interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:24055]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0051117//ATPase binding	GO:0007029//endoplasmic reticulum organization;GO:0032781//positive regulation of ATPase activity;GO:0061024//membrane organization;GO:0090435//protein localization to nuclear envelope	--
ENSG00000169906	0	0	0	0	0	0	0	0	0	0	0	0	S100G	S100 calcium binding protein G [Source:HGNC Symbol;Acc:HGNC:1436]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14734	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0005499//vitamin D binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000169908	8.294	9.105	7.869	3.641	3.913	5.003	264	290	181	87	105	112	TM4SF1	transmembrane 4 L six family member 1 [Source:HGNC Symbol;Acc:HGNC:11853]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001825//blastocyst formation;GO:0008150//biological_process	--
ENSG00000169914	1.894	1.693	2.044	1.598	1.647	1.536	256	230	204	160	188	151	OTUD3	OTU deubiquitinase 3 [Source:HGNC Symbol;Acc:HGNC:29038]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0044313//protein K6-linked deubiquitination;GO:0050821//protein stabilization;GO:0051898//negative regulation of protein kinase B signaling;GO:0071108//protein K48-linked deubiquitination;GO:1990167//protein K27-linked deubiquitination	--
ENSG00000169918	0.33	0.288	0.533	0.383	0.563	0.347	45	43	64	37	56	33	OTUD7A	OTU deubiquitinase 7A [Source:HGNC Symbol;Acc:HGNC:20718]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process	--
ENSG00000169919	26.568	28.045	29.863	28.529	27.953	26.025	1207	1270	1006	955	1071	863	GUSB	glucuronidase beta [Source:HGNC Symbol;Acc:HGNC:4696]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Xenobiotics biodegradation and metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00983//Drug metabolism - other enzymes;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism;ko00531//Glycosaminoglycan degradation	K01195;K01195;K01195;K01195;K01195;K01195;K01195	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004566//beta-glucuronidase activity;GO:0005102//signaling receptor binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019904//protein domain specific binding;GO:0030246//carbohydrate binding"	GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008152//metabolic process;GO:0019391//glucuronoside catabolic process	--
ENSG00000169925	18.534	17.325	17.592	15.117	15.7	19.727	1987.91	1879.88	1485.09	1197.95	1462.19	1483.14	BRD3	bromodomain containing 3 [Source:HGNC Symbol;Acc:HGNC:1104]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031493//nucleosomal histone binding;GO:0070577//lysine-acetylated histone binding	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	--
ENSG00000169926	10.178	10.7	10.442	9.375	9.904	10.348	1445	1527	1095	986	1188	1069	KLF13	Kruppel like factor 13 [Source:HGNC Symbol;Acc:HGNC:13672]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000169933	0.024	0.034	0.076	0.113	0	0.065	4	3	7	5	0	8	FRMPD4	FERM and PDZ domain containing 4 [Source:HGNC Symbol;Acc:HGNC:29007]	-	-	-	-	GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098978//glutamatergic synapse	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding"	GO:0051835//positive regulation of synapse structural plasticity;GO:0098974//postsynaptic actin cytoskeleton organization	--
ENSG00000169946	1.822	1.317	1.089	0.48	1.017	0.516	158	122	67	32	67	34	ZFPM2	"zinc finger protein, FOG family member 2 [Source:HGNC Symbol;Acc:HGNC:16700]"	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K17442	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0003148//outflow tract septum morphogenesis;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007506//gonadal mesoderm development;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0010604//positive regulation of macromolecule metabolic process;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0045595//regulation of cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development;GO:0048568//embryonic organ development;GO:0048738//cardiac muscle tissue development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060412//ventricular septum morphogenesis;GO:0060548//negative regulation of cell death;GO:2000020//positive regulation of male gonad development;GO:2000195//negative regulation of female gonad development"	zf-C2H2
ENSG00000169951	2.575	3.084	2.477	3.039	3.222	3.108	152	183	108	132	159	131	ZNF764	zinc finger protein 764 [Source:HGNC Symbol;Acc:HGNC:28200]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000169953	0	0	0	0	0	0	0	0	0	0	0	0	HSFY2	heat shock transcription factor Y-linked 2 [Source:HGNC Symbol;Acc:HGNC:23950]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000169955	6.709	7.193	7.459	6.809	7.167	7.399	391	417	339	320.99	378	342	ZNF747	zinc finger protein 747 [Source:HGNC Symbol;Acc:HGNC:28350]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000169957	18.863	19.015	21.819	22.924	24.084	25.01	868	904	737	779	914	827	ZNF768	zinc finger protein 768 [Source:HGNC Symbol;Acc:HGNC:26273]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II	zf-C2H2
ENSG00000169962	0.624	0.538	0.827	0.805	0.739	0.648	45	39	44	43	45	34	TAS1R3	taste 1 receptor member 3 [Source:HGNC Symbol;Acc:HGNC:15661]	Organismal Systems;Organismal Systems	Sensory system;Digestive system	ko04742//Taste transduction;ko04973//Carbohydrate digestion and absorption	K04626;K04626	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1903767//sweet taste receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033041//sweet taste receptor activity	GO:0001582//detection of chemical stimulus involved in sensory perception of sweet taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050916//sensory perception of sweet taste;GO:0050917//sensory perception of umami taste	--
ENSG00000169964	6.464	7.953	7.015	5.729	7.184	5.697	131	162	105	86	123	84	TMEM42	transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000169967	8.605	5.683	6.077	3.967	4.028	5.905	1576	944	725	495	613	618	MAP3K2	mitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6854]	Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Endocrine system;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko04912//GnRH signaling pathway;ko04540//Gap junction	K04420;K04420;K04420	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071260//cellular response to mechanical stimulus"	--
ENSG00000169972	8.396	9.906	10.103	9.807	8.919	11.89	213	256	190	182	195	210	PUSL1	pseudouridine synthase like 1 [Source:HGNC Symbol;Acc:HGNC:26914]	-	-	-	-	GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0106029//tRNA pseudouridine synthase activity	GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0031119//tRNA pseudouridine synthesis	--
ENSG00000169976	58.343	62.215	71.9	76.594	68.147	61.555	835	895	760	812	824	641	SF3B5	splicing factor 3b subunit 5 [Source:HGNC Symbol;Acc:HGNC:21083]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12832	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:1990935//splicing factor binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006282//regulation of DNA repair;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000169981	3.273	2.456	3.123	3.043	2.803	2.263	151	118	93	62	113	89	ZNF35	zinc finger protein 35 [Source:HGNC Symbol;Acc:HGNC:13099]	-	-	-	-	GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0071300//cellular response to retinoic acid"	zf-C2H2
ENSG00000169989	0.633	0.334	0.509	0.32	0.211	0.516	32	17	19	12	9	19	TIGD4	tigger transposable element derived 4 [Source:HGNC Symbol;Acc:HGNC:18335]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000169991	4.999	3.73	4.803	4.74	5.818	5.277	409	351	275	249	369	307	IFFO2	intermediate filament family orphan 2 [Source:HGNC Symbol;Acc:HGNC:27006]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000169992	11.972	12.42	14.552	12.183	14.518	15.274	1112	1064	878	828	1096	932	NLGN2	neuroligin 2 [Source:HGNC Symbol;Acc:HGNC:14290]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07378	"GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0060077//inhibitory synapse;GO:0089717//spanning component of membrane;GO:0097470//ribbon synapse;GO:0098690//glycinergic synapse;GO:0098691//dopaminergic synapse;GO:0098982//GABA-ergic synapse;GO:0098983//symmetric, GABA-ergic, inhibitory synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding	"GO:0001966//thigmotaxis;GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0007420//brain development;GO:0007630//jump response;GO:0008284//positive regulation of cell population proliferation;GO:0019233//sensory perception of pain;GO:0032024//positive regulation of insulin secretion;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0034394//protein localization to cell surface;GO:0035176//social behavior;GO:0035418//protein localization to synapse;GO:0035641//locomotory exploration behavior;GO:0045217//cell-cell junction maintenance;GO:0048488//synaptic vesicle endocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0050885//neuromuscular process controlling balance;GO:0051932//synaptic transmission, GABAergic;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060999//positive regulation of dendritic spine development;GO:0072553//terminal button organization;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:0098609//cell-cell adhesion;GO:0098698//postsynaptic specialization assembly;GO:0099054//presynapse assembly;GO:1901142//insulin metabolic process;GO:1902474//positive regulation of protein localization to synapse;GO:1904034//positive regulation of t-SNARE clustering;GO:1904862//inhibitory synapse assembly;GO:1905606//regulation of presynapse assembly;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000809//positive regulation of synaptic vesicle clustering"	--
ENSG00000169994	0.014	0.021	0	0	0	0.186	1	3	0	0	0	3	MYO7B	myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0005903//brush border;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0031982//vesicle;GO:0042995//cell projection;GO:0090651//apical cytoplasm;GO:0120025//plasma membrane bounded cell projection	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007423//sensory organ development;GO:0007605//sensory perception of sound;GO:0030050//vesicle transport along actin filament;GO:0030154//cell differentiation;GO:1904970//brush border assembly	--
ENSG00000170004	56.756	63.053	54.693	55.635	53.5	48.533	6876	6941	5153	4721	5517	4250	CHD3	chromodomain helicase DNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:1918]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016581//NuRD complex;GO:0016605//PML body;GO:0034451//centriolar satellite;GO:0043233//organelle lumen	GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140658//ATP-dependent chromatin remodeler activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006333//chromatin assembly or disassembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007051//spindle organization;GO:0007098//centrosome cycle;GO:0016575//histone deacetylation;GO:0032508//DNA duplex unwinding;GO:0042659//regulation of cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000736//regulation of stem cell differentiation"	--
ENSG00000170006	0.009	0.018	0	0.006	0.005	0	2	4	0	1	1	0	TMEM154	transmembrane protein 154 [Source:HGNC Symbol;Acc:HGNC:26489]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000170011	73.323	70.939	66.469	54.263	62.297	65.225	7298	6883	4781	4018	5114	4797	MYRIP	myosin VIIA and Rab interacting protein [Source:HGNC Symbol;Acc:HGNC:19156]	-	-	-	-	GO:0000145//exocyst;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030133//transport vesicle;GO:0030864//cortical actin cytoskeleton;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0042470//melanosome;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017022//myosin binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0051018//protein kinase A binding	GO:0006886//intracellular protein transport;GO:0032024//positive regulation of insulin secretion	--
ENSG00000170017	9.331	8.069	4.388	4.413	5.801	4.994	752	659	292	259	353	311	ALCAM	activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06547	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031226//intrinsic component of plasma membrane;GO:0042101//T cell receptor complex;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0031290//retinal ganglion cell axon guidance;GO:0048846//axon extension involved in axon guidance;GO:1990138//neuron projection extension	--
ENSG00000170027	48.55	45.013	49.861	45.112	46.391	55.459	3731	3477	2830	2568	3012	3101	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma [Source:HGNC Symbol;Acc:HGNC:12852]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cancer: overview;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death	ko04151//PI3K-Akt signaling pathway;ko05203//Viral carcinogenesis;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04114//Oocyte meiosis;ko04110//Cell cycle	K16198;K16198;K16198;K16198;K16198;K16198	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031982//vesicle;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0008426//protein kinase C inhibitor activity;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding;GO:0042802//identical protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0009966//regulation of signal transduction;GO:0032869//cellular response to insulin stimulus;GO:0034613//cellular protein localization;GO:0045664//regulation of neuron differentiation;GO:0048167//regulation of synaptic plasticity	--
ENSG00000170035	55.404	55.617	52.255	47.035	46.035	55.399	1436	1401	1019	933	993	992	UBE2E3	ubiquitin conjugating enzyme E2 E3 [Source:HGNC Symbol;Acc:HGNC:12479]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K20217	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0040008//regulation of growth;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000170037	9.348	8.869	6.848	8.372	9.83	8.109	434	448	282	317	391	277	CNTROB	"centrobin, centriole duplication and spindle assembly protein [Source:HGNC Symbol;Acc:HGNC:29616]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0051299//centrosome separation;GO:0051301//cell division;GO:1902017//regulation of cilium assembly;GO:1902410//mitotic cytokinetic process	--
ENSG00000170043	41.119	40.579	46.847	50.056	50.462	39.706	683	674	573	596	613	470	TRAPPC1	trafficking protein particle complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:19894]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0035578//azurophil granule lumen;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000170044	3.025	3.25	2.177	1.759	1.677	2.661	213	224	112	85	96	127	ZPLD1	zona pellucida like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27022]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005201//extracellular matrix structural constituent	GO:0060005//vestibular reflex	--
ENSG00000170049	0.301	0.083	0.476	0.393	0.277	0.322	18	5	21	16	14	14	KCNAB3	potassium voltage-gated channel subfamily A regulatory beta subunit 3 [Source:HGNC Symbol;Acc:HGNC:6230]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016021//integral component of membrane	GO:0004033//aldo-keto reductase (NADP) activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000170054	0.068	0.083	0.086	0.113	0.04	0	2	2	2	2	1	0	SERPINA9	serpin family A member 9 [Source:HGNC Symbol;Acc:HGNC:15995]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000170074	0.044	0.011	0	0	0	0	1.5	1	0	0	0	0	FAM153A	family with sequence similarity 153 member A [Source:HGNC Symbol;Acc:HGNC:29940]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000170075	0.483	0.749	0.634	0.438	0.764	0.661	21	45	23	14	36	22	GPR37L1	G protein-coupled receptor 37 like 1 [Source:HGNC Symbol;Acc:HGNC:14923]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0036505//prosaposin receptor activity;GO:0042277//peptide binding	GO:0003085//negative regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0045665//negative regulation of neuron differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048712//negative regulation of astrocyte differentiation;GO:1903206//negative regulation of hydrogen peroxide-induced cell death	--
ENSG00000170085	3.18	3.062	2.96	2.619	2.883	2.406	218	211	141	133	167	120	SIMC1	SUMO interacting motifs containing 1 [Source:HGNC Symbol;Acc:HGNC:24779]	-	-	-	-	GO:0005737//cytoplasm;GO:0030017//sarcomere	GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0032184//SUMO polymer binding	GO:0010466//negative regulation of peptidase activity	--
ENSG00000170088	19.554	16.814	17.013	15.186	16.522	16.753	1279	1090	825	718	869	786	TMEM192	transmembrane protein 192 [Source:HGNC Symbol;Acc:HGNC:26775]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0042803//protein homodimerization activity	-	--
ENSG00000170091	0.328	0.225	0.167	0.083	0.024	0	16	11	6	3	1	0	NSG2	neuronal vesicle trafficking associated 2 [Source:HGNC Symbol;Acc:HGNC:24955]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032580//Golgi cisterna membrane;GO:0032585//multivesicular body membrane;GO:0032588//trans-Golgi network membrane;GO:0042995//cell projection;GO:0043202//lysosomal lumen;GO:1990674//Golgi cis cisterna membrane	GO:0005515//protein binding;GO:0032051//clathrin light chain binding	GO:0007212//dopamine receptor signaling pathway;GO:0016197//endosomal transport;GO:0048268//clathrin coat assembly	--
ENSG00000170092	0.044	0.015	0	0.021	0.052	0	3	1	0	1.07	3	0	SPDYE5	speedy/RINGO cell cycle regulator family member E5 [Source:HGNC Symbol;Acc:HGNC:35464]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000170099	0	0.065	0	0	0	0	0	2	0	0	0	0	SERPINA6	serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005496//steroid binding;GO:0008289//lipid binding	GO:0008211//glucocorticoid metabolic process;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000170100	3.832	3.332	2.965	2.145	4.572	3.338	363	332	255	196	272	212	ZNF778	zinc finger protein 778 [Source:HGNC Symbol;Acc:HGNC:26479]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000170113	7.699	6.43	6.13	5.748	6.243	7.1	820	830	596	547	630	634	NIPA1	NIPA magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:17043]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015693//magnesium ion transport;GO:0055085//transmembrane transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000170122	0.066	0.11	0.298	0.149	0.13	0.091	3	5	10	5	5	3	FOXD4	forkhead box D4 [Source:HGNC Symbol;Acc:HGNC:3805]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000170128	0	0	0	0	0	0	0	0	0	0	0	0	GPR25	G protein-coupled receptor 25 [Source:HGNC Symbol;Acc:HGNC:4480]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000170142	43.861	39.282	37.875	37.311	27.319	42.274	1178.98	1144.48	854.28	720.05	729.52	832.68	UBE2E1	ubiquitin conjugating enzyme E2 E1 [Source:HGNC Symbol;Acc:HGNC:12477]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K20217	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0042296//ISG15 transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010390//histone monoubiquitination;GO:0016567//protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0032446//protein modification by small protein conjugation;GO:0033523//histone H2B ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000170144	67.198	60.794	62.559	61.982	63.48	66.545	4066	3565	2679	2583	3130	2795	HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12741;K12741	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000170145	13.278	12.273	13.487	10.491	10.93	12.134	2650	2462	1988	1551	1843	1762	SIK2	salt inducible kinase 2 [Source:HGNC Symbol;Acc:HGNC:21680]	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K16311	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046777//protein autophosphorylation	--
ENSG00000170153	19.748	18.265	17.373	12.191	15.432	15.093	4097	3763	2575	1836	2560	2276	RNF150	ring finger protein 150 [Source:HGNC Symbol;Acc:HGNC:23138]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000170160	0.142	0.075	0.043	0.067	0.289	0.103	24.78	13.52	5.74	9	13.83	12.87	CCDC144A	coiled-coil domain containing 144A [Source:HGNC Symbol;Acc:HGNC:29072]	-	-	-	-	-	GO:0046904//calcium oxalate binding	-	--
ENSG00000170162	0.043	0.087	0.029	0.204	0.205	0.244	2	4	1	7	8	8	VGLL2	vestigial like family member 2 [Source:HGNC Symbol;Acc:HGNC:20232]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000170166	0	0	0	0	0	0	0	0	0	0	0	0	HOXD4	homeobox D4 [Source:HGNC Symbol;Acc:HGNC:5138]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000170175	25.558	25.454	26.4	18.805	19.495	21.494	1109	1099	787	541	636	608	CHRNB1	cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04812	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015267//channel activity;GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001941//postsynaptic membrane organization;GO:0003009//skeletal muscle contraction;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007274//neuromuscular synaptic transmission;GO:0034220//ion transmembrane transport;GO:0035095//behavioral response to nicotine;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0055001//muscle cell development;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential"	--
ENSG00000170178	0	0	0	0	0	0	0	0	0	0	0	0	HOXD12	homeobox D12 [Source:HGNC Symbol;Acc:HGNC:5135]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0042733//embryonic digit morphogenesis"	Homeobox
ENSG00000170180	0	0.128	0	0	0.193	0.088	0	2	0	0	4	1	GYPA	glycophorin A (MNS blood group) [Source:HGNC Symbol;Acc:HGNC:4702]	Organismal Systems;Human Diseases	Immune system;Infectious disease: parasitic	ko04640//Hematopoietic cell lineage;ko05144//Malaria	K06575;K06575	GO:0005575//cellular_component;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008150//biological_process;GO:0046718//viral entry into host cell	--
ENSG00000170185	14.27	11.857	11.537	11.167	11.111	12.555	1384	1172	801	804	937	864	USP38	ubiquitin specific peptidase 38 [Source:HGNC Symbol;Acc:HGNC:20067]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000170190	2.783	3.028	2.161	4.498	3.624	2.911	113	123	64	131	120	85	SLC16A5	solute carrier family 16 member 5 [Source:HGNC Symbol;Acc:HGNC:10926]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport	--
ENSG00000170191	2.726	2.787	2.952	2.276	2.446	2.84	215	221	172	133	163	163	NANP	N-acetylneuraminic acid phosphatase [Source:HGNC Symbol;Acc:HGNC:16140]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01097;K01097	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0016787//hydrolase activity;GO:0050124//N-acylneuraminate-9-phosphatase activity	GO:0005975//carbohydrate metabolic process;GO:0006045//N-acetylglucosamine biosynthetic process;GO:0016311//dephosphorylation;GO:0046380//N-acetylneuraminate biosynthetic process	--
ENSG00000170209	0.094	0.301	0.358	0.153	0.201	0.156	5	16	14	6	9	6	ANKK1	ankyrin repeat and kinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21027]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0010564//regulation of cell cycle process;GO:0016310//phosphorylation	--
ENSG00000170214	0.019	0.057	0	0.052	0.091	0.106	1	3	0	2	4	4	ADRA1B	adrenoceptor alpha 1B [Source:HGNC Symbol;Acc:HGNC:278]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Circulatory system;Circulatory system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04970//Salivary secretion	K04136;K04136;K04136;K04136;K04136;K04136	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004937//alpha1-adrenergic receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0006937//regulation of muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0019229//regulation of vasoconstriction;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0045907//positive regulation of vasoconstriction;GO:0055117//regulation of cardiac muscle contraction;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0150099//neuron-glial cell signaling	--
ENSG00000170222	3.028	3.056	3.094	3.047	2.799	3.197	89	89	62	63	70	68	ADPRM	"ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [Source:HGNC Symbol;Acc:HGNC:30925]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00564//Glycerophospholipid metabolism	K01517;K01517;K01517	GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0008663//2',3'-cyclic-nucleotide 2'-phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity;GO:0047734//CDP-glycerol diphosphatase activity"	-	--
ENSG00000170231	0	0	0	0	0	0.134	0	0	0	0	0	1	FABP6	fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K08755	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005504//fatty acid binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008285//negative regulation of cell population proliferation;GO:0015908//fatty acid transport	--
ENSG00000170234	6.371	5.315	4.198	3.889	3.562	4.061	316	255	170	199	201	189	PWWP2A	PWWP domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29406]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031493//nucleosomal histone binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0120325//NuRD complex binding	"GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0035067//negative regulation of histone acetylation;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:2000142//regulation of DNA-templated transcription, initiation;GO:2000616//negative regulation of histone H3-K9 acetylation"	--
ENSG00000170236	0	0	0	0	0	0	0	0	0	0	0	0	USP50	ubiquitin specific peptidase 50 [Source:HGNC Symbol;Acc:HGNC:20079]	-	-	-	-	GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0019897//extrinsic component of plasma membrane;GO:0030496//midbody;GO:0031313//extrinsic component of endosome membrane;GO:0043197//dendritic spine	GO:0004843//thiol-dependent deubiquitinase;GO:0019783//ubiquitin-like protein-specific protease activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007032//endosome organization;GO:0007265//Ras protein signal transduction;GO:0016579//protein deubiquitination;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032741//positive regulation of interleukin-18 production;GO:0035063//nuclear speck organization;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000170242	9.301	6.32	6.044	5.079	5.152	5.582	1548.06	1058.07	728.62	610.48	731.46	661.41	USP47	ubiquitin specific peptidase 47 [Source:HGNC Symbol;Acc:HGNC:20076]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0071987//WD40-repeat domain binding;GO:0101005//deubiquitinase activity	"GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0030307//positive regulation of cell growth;GO:0031647//regulation of protein stability;GO:0034644//cellular response to UV;GO:0035520//monoubiquitinated protein deubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage"	--
ENSG00000170248	20.729	18.563	18.672	16.291	18.83	17.842	2529	2058	1635	1376	1811	1589	PDCD6IP	programmed cell death 6 interacting protein [Source:HGNC Symbol;Acc:HGNC:8766]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12200	GO:0001772//immunological synapse;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005923//bicellular tight junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0042470//melanosome;GO:0042641//actomyosin;GO:0070062//extracellular exosome;GO:0070971//endoplasmic reticulum exit site;GO:0090543//Flemming body;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0031871//proteinase activated receptor binding;GO:0042803//protein homodimerization activity;GO:0048306//calcium-dependent protein binding	GO:0000281//mitotic cytokinesis;GO:0000915//actomyosin contractile ring assembly;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0046755//viral budding;GO:0051260//protein homooligomerization;GO:0051301//cell division;GO:0061952//midbody abscission;GO:0070830//bicellular tight junction assembly;GO:0071985//multivesicular body sorting pathway;GO:0090559//regulation of membrane permeability;GO:0090611//ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway;GO:1903543//positive regulation of exosomal secretion;GO:1903551//regulation of extracellular exosome assembly;GO:1903553//positive regulation of extracellular exosome assembly	--
ENSG00000170255	0	0	0	0	0	0	0	0	0	0	0	0	MRGPRX1	MAS related GPR family member X1 [Source:HGNC Symbol;Acc:HGNC:17962]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0006953//acute-phase response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:1902349//response to chloroquine	--
ENSG00000170260	6.489	6.722	4.605	5.889	4.879	6.232	363	387	198	249	240	246	ZNF212	zinc finger protein 212 [Source:HGNC Symbol;Acc:HGNC:13004]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000170262	0	0	0	0	0	0	0	0	0	0	0	0	MRAP	melanocortin 2 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:1304]	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Endocrine system	ko04934//Cushing syndrome;ko04927//Cortisol synthesis and secretion	K22398;K22398	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0030545//signaling receptor regulator activity;GO:0031780//corticotropin hormone receptor binding;GO:0031781//type 3 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0031783//type 5 melanocortin receptor binding;GO:0042802//identical protein binding;GO:0070996//type 1 melanocortin receptor binding	GO:0072659//protein localization to plasma membrane;GO:0106070//regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0106071//positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0106072//negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000170264	13.596	11.253	10.265	6.747	9.321	7.832	1019	843	556	371	575	411	FAM161A	FAM161 centrosomal protein A [Source:HGNC Symbol;Acc:HGNC:25808]	-	-	-	-	GO:0000235//astral microtubule;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005929//cilium;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding	GO:0007601//visual perception;GO:0030030//cell projection organization;GO:0044782//cilium organization;GO:0050896//response to stimulus;GO:0060271//cilium assembly;GO:1901985//positive regulation of protein acetylation	--
ENSG00000170265	11.599	12.196	13.793	14.352	14.133	12.123	830	877	743	730	839	668	ZNF282	zinc finger protein 282 [Source:HGNC Symbol;Acc:HGNC:13076]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000170266	75.166	81.486	81.28	69.703	75.388	79.132	3746	4155	3012	2623	3252	2872	GLB1	galactosidase beta 1 [Source:HGNC Symbol;Acc:HGNC:4298]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00600//Sphingolipid metabolism;ko00052//Galactose metabolism;ko00531//Glycosaminoglycan degradation;ko00511//Other glycan degradation;ko00604//Glycosphingolipid biosynthesis - ganglio series	K12309;K12309;K12309;K12309;K12309;K12309;K12309	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005773//vacuole;GO:0005794//Golgi apparatus;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004565//beta-galactosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016936//galactoside binding;GO:0042803//protein homodimerization activity"	GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0008152//metabolic process;GO:0019388//galactose catabolic process;GO:0042340//keratan sulfate catabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0051413//response to cortisone;GO:1904016//response to Thyroglobulin triiodothyronine	--
ENSG00000170270	10.799	11.043	11.721	10.125	8.522	11.367	252	259	202	175	168	193	GON7	GON7 subunit of KEOPS complex [Source:HGNC Symbol;Acc:HGNC:20356]	-	-	-	-	GO:0000408//EKC/KEOPS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002949//tRNA threonylcarbamoyladenosine modification	--
ENSG00000170271	14.191	14.66	20.52	19.228	16.856	20.828	846	870	867	844	851	899	FAXDC2	fatty acid hydroxylase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:1334]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000254//C-4 methylsterol oxidase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0008610//lipid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0045654//positive regulation of megakaryocyte differentiation	--
ENSG00000170275	120.337	118.628	116.814	122.807	122.105	117.572	9610	9537	7004	7242	7771	6866	CRTAP	cartilage associated protein [Source:HGNC Symbol;Acc:HGNC:2379]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0005518//collagen binding	GO:0007283//spermatogenesis;GO:0018400//peptidyl-proline hydroxylation to 3-hydroxy-L-proline;GO:0030199//collagen fibril organization;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:1901874//negative regulation of post-translational protein modification	--
ENSG00000170276	0.515	0.683	0.697	1.776	0.745	0.786	9	12	9	23	11	10	HSPB2	heat shock protein family B (small) member 2 [Source:HGNC Symbol;Acc:HGNC:5247]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K09543	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0006986//response to unfolded protein;GO:0050790//regulation of catalytic activity	--
ENSG00000170279	0	0	0.113	0.056	0	0	0	0	2	1	0	0	C7orf33	chromosome 7 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:21724]	-	-	-	-	-	-	-	--
ENSG00000170289	20.004	18.913	16.817	6.93	9.189	8.764	1727	1642	1077	449	680	552	CNGB3	cyclic nucleotide gated channel subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:2153]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K04953	GO:0001750//photoreceptor outer segment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1902495//transmembrane transporter complex	GO:0000166//nucleotide binding;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0030553//cGMP binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0098655//cation transmembrane transport	--
ENSG00000170290	0.2	0.066	0.181	0.09	0	0	3	1	2	1	0	0	SLN	sarcolipin [Source:HGNC Symbol;Acc:HGNC:11089]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0051117//ATPase binding	GO:0006816//calcium ion transport;GO:0043086//negative regulation of catalytic activity;GO:0043242//negative regulation of protein-containing complex disassembly;GO:0050790//regulation of catalytic activity;GO:0051924//regulation of calcium ion transport;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0090281//negative regulation of calcium ion import;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1901077//regulation of relaxation of muscle;GO:1901877//negative regulation of calcium ion binding;GO:1901881//positive regulation of protein depolymerization;GO:1901894//regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity	--
ENSG00000170291	15.068	14.733	16.395	18.878	16.478	17.149	507	486	387	423	463	424	ELP5	elongator acetyltransferase complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:30617]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0033588//elongator holoenzyme complex	GO:0000049//tRNA binding;GO:0005515//protein binding	GO:0002098//tRNA wobble uridine modification;GO:0006400//tRNA modification;GO:0006417//regulation of translation;GO:0008033//tRNA processing;GO:0030335//positive regulation of cell migration	--
ENSG00000170293	3.506	4.513	4.148	5.264	3.563	4.648	85	110	74	93	73	82	CMTM8	CKLF like MARVEL transmembrane domain containing 8 [Source:HGNC Symbol;Acc:HGNC:19179]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath	GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0042552//myelination	--
ENSG00000170296	456.723	458.062	477.181	547.646	462.104	505.136	7783.2	8139.62	5783	6783	6942	6093.98	GABARAP	GABA type A receptor-associated protein [Source:HGNC Symbol;Acc:HGNC:4067]	Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Cellular Processes	Immune system;Transport and catabolism;Signal transduction;Nervous system;Transport and catabolism;Transport and catabolism	ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04727//GABAergic synapse;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K08341;K08341;K08341;K08341;K08341;K08341	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005776//autophagosome;GO:0005790//smooth endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005930//axoneme;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0097225//sperm midpiece	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding;GO:0048487//beta-tubulin binding;GO:0050811//GABA receptor binding	GO:0000045//autophagosome assembly;GO:0000226//microtubule cytoskeleton organization;GO:0000422//autophagy of mitochondrion;GO:0006605//protein targeting;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0006995//cellular response to nitrogen starvation;GO:0007268//chemical synaptic transmission;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035020//regulation of Rac protein signal transduction;GO:1902524//positive regulation of protein K48-linked ubiquitination	--
ENSG00000170298	0	0	0	0.058	0.066	0	0	0	0	1	2	0	LGALS9B	galectin 9B [Source:HGNC Symbol;Acc:HGNC:24842]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	"GO:0010628//positive regulation of gene expression;GO:0032689//negative regulation of interferon-gamma production;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000170310	11.645	17.57	17.179	18.954	13.448	13.399	194	296	210	226	190	155	STX8	syntaxin 8 [Source:HGNC Symbol;Acc:HGNC:11443]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08501	GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0019869//chloride channel inhibitor activity;GO:0019905//syntaxin binding;GO:0031625//ubiquitin protein ligase binding	GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0008333//endosome to lysosome transport;GO:0016192//vesicle-mediated transport;GO:0045022//early endosome to late endosome transport;GO:0048278//vesicle docking;GO:0071346//cellular response to interferon-gamma;GO:1903076//regulation of protein localization to plasma membrane	--
ENSG00000170312	8.238	7.677	5.975	2.102	2.506	3.38	322	302	172	61	83	91	CDK1	cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Organismal Systems;Cellular Processes;Cellular Processes	Infectious disease: viral;Cancer: overview;Cell growth and death;Cell growth and death;Cell growth and death;Endocrine system;Cellular community - eukaryotes;Cell growth and death	ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko04218//Cellular senescence;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation;ko04540//Gap junction;ko04115//p53 signaling pathway	K02087;K02087;K02087;K02087;K02087;K02087;K02087;K02087	"GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0016020//membrane;GO:0030496//midbody;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0097125//cyclin B1-CDK1 complex"	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008353//RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030332//cyclin binding;GO:0030544//Hsp70 protein binding;GO:0035173//histone kinase activity;GO:0097472//cyclin-dependent protein kinase activity;GO:0106310//protein serine kinase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007098//centrosome cycle;GO:0007344//pronuclear fusion;GO:0007569//cell aging;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0010243//response to organonitrogen compound;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014038//regulation of Schwann cell differentiation;GO:0014070//response to organic cyclic compound;GO:0014075//response to amine;GO:0014823//response to activity;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0016572//histone phosphorylation;GO:0016579//protein deubiquitination;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030261//chromosome condensation;GO:0030855//epithelial cell differentiation;GO:0031100//animal organ regeneration;GO:0034501//protein localization to kinetochore;GO:0042307//positive regulation of protein import into nucleus;GO:0042542//response to hydrogen peroxide;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0044772//mitotic cell cycle phase transition;GO:0045471//response to ethanol;GO:0045740//positive regulation of DNA replication;GO:0045931//positive regulation of mitotic cell cycle;GO:0045995//regulation of embryonic development;GO:0046686//response to cadmium ion;GO:0046688//response to copper ion;GO:0046718//viral entry into host cell;GO:0048511//rhythmic process;GO:0048678//response to axon injury;GO:0051301//cell division;GO:0055015//ventricular cardiac muscle cell development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0065003//protein-containing complex assembly;GO:0070301//cellular response to hydrogen peroxide;GO:0070371//ERK1 and ERK2 cascade;GO:0090166//Golgi disassembly;GO:1900182//positive regulation of protein localization to nucleus;GO:1905448//positive regulation of mitochondrial ATP synthesis coupled electron transport	--
ENSG00000170315	689.678	729.153	740.177	762.323	741.808	727.022	12942	13768	10262	10560	11795	9907	UBB	ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Folding, sorting and degradation;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04120//Ubiquitin mediated proteolysis;ko04137//Mitophagy - animal	K04551;K04551;K04551;K04551;K04551;K04551	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0030666//endocytic vesicle membrane;GO:0031315//extrinsic component of mitochondrial outer membrane;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding	GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0021888//hypothalamus gonadotrophin-releasing hormone neuron development;GO:0031398//positive regulation of protein ubiquitination;GO:0047497//mitochondrion transport along microtubule;GO:0048812//neuron projection morphogenesis;GO:0051881//regulation of mitochondrial membrane potential;GO:0060612//adipose tissue development;GO:0060613//fat pad development;GO:0061136//regulation of proteasomal protein catabolic process;GO:0072520//seminiferous tubule development;GO:0097009//energy homeostasis;GO:1901214//regulation of neuron death;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1902527//positive regulation of protein monoubiquitination	--
ENSG00000170322	6.391	7.026	7.426	8.042	8.206	7.278	631	693	472	551	679	497	NFRKB	nuclear factor related to kappaB binding protein [Source:HGNC Symbol;Acc:HGNC:7802]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:1904507//positive regulation of telomere maintenance in response to DNA damage"	Others
ENSG00000170323	0.106	0.316	0	0.236	2.819	0.436	2	6	0	3	45	6	FABP4	fatty acid binding protein 4 [Source:HGNC Symbol;Acc:HGNC:3559]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko03320//PPAR signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K08753;K08753	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005324//long-chain fatty acid transporter activity;GO:0005504//fatty acid binding;GO:0008289//lipid binding;GO:0036041//long-chain fatty acid binding;GO:0051427//hormone receptor binding	"GO:0006469//negative regulation of protein kinase activity;GO:0009617//response to bacterium;GO:0015908//fatty acid transport;GO:0015909//long-chain fatty acid transport;GO:0042632//cholesterol homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050872//white fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0071285//cellular response to lithium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000170324	0.023	0.011	0	0.047	0.037	0.016	2	1	0	3	3	1	FRMPD2	FERM and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28572]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding	GO:0070830//bicellular tight junction assembly	--
ENSG00000170325	2.522	2.739	2.753	2.312	2.226	2.799	317	347	265	224	246	264	PRDM10	PR/SET domain 10 [Source:HGNC Symbol;Acc:HGNC:13995]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0010468//regulation of gene expression;GO:0032259//methylation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000170340	19.497	16.269	17.834	15.758	14.331	17.867	1080	919	735	657	688	737	B3GNT2	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:15629]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K00741;K00741;K00741	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0008457//beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity"	GO:0006486//protein glycosylation;GO:0007411//axon guidance;GO:0007608//sensory perception of smell;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0030311//poly-N-acetyllactosamine biosynthetic process;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000170345	1.951	1.733	1.877	1.423	1.77	1.606	84	76	58	46	61	51	FOS	"Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Endocrine and metabolic disease;Infectious disease: viral;Immune disease;Endocrine system;Immune system;Cancer: specific types;Infectious disease: viral;Infectious disease: parasitic;Cell growth and death;Cardiovascular disease;Endocrine system;Nervous system;Endocrine system;Development and regeneration;Endocrine system;Nervous system;Signal transduction;Immune system;Immune system;Infectious disease: parasitic;Endocrine system;Immune system;Cancer: overview;Environmental adaptation;Drug resistance: antineoplastic;Immune system;Cancer: overview;Immune system;Cancer: specific types;Infectious disease: bacterial;Endocrine system;Substance dependence	"ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05162//Measles;ko05140//Leishmaniasis;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04928//Parathyroid hormone synthesis, secretion and action;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04713//Circadian entrainment;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05210//Colorectal cancer;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko05031//Amphetamine addiction"	K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379;K04379	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0032993//protein-DNA complex;GO:0035976//transcription factor AP-1 complex;GO:0043005//neuron projection;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412//R-SMAD binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001661//conditioned taste aversion;GO:0006306//DNA methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006954//inflammatory response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007399//nervous system development;GO:0007565//female pregnancy;GO:0007568//aging;GO:0009409//response to cold;GO:0009410//response to xenobiotic stimulus;GO:0009416//response to light stimulus;GO:0009612//response to mechanical stimulus;GO:0009629//response to gravity;GO:0009636//response to toxic substance;GO:0010468//regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0030431//sleep;GO:0031668//cellular response to extracellular stimulus;GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone;GO:0032870//cellular response to hormone stimulus;GO:0034097//response to cytokine;GO:0034614//cellular response to reactive oxygen species;GO:0035902//response to immobilization stress;GO:0035914//skeletal muscle cell differentiation;GO:0035994//response to muscle stretch;GO:0045672//positive regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051412//response to corticosterone;GO:0051591//response to cAMP;GO:0060395//SMAD protein signal transduction;GO:0071276//cellular response to cadmium ion;GO:0071277//cellular response to calcium ion;GO:0140467//integrated stress response signaling;GO:1901216//positive regulation of neuron death;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	TF_bZIP
ENSG00000170348	143.91	143.439	140.526	142.049	131.774	132.71	11158	11172	7879	7797	8861	7644	TMED10	transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K20352	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030137//COPI-coated vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030658//transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042470//melanosome;GO:0042589//zymogen granule membrane;GO:0070765//gamma-secretase complex	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0019905//syntaxin binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032732//positive regulation of interleukin-1 production;GO:0035459//vesicle cargo loading;GO:0035964//COPI-coated vesicle budding;GO:0045055//regulated exocytosis;GO:0048199//vesicle targeting, to, from or within Golgi;GO:0048205//COPI coating of Golgi vesicle;GO:0048208//COPII vesicle coating;GO:0050714//positive regulation of protein secretion;GO:0071806//protein transmembrane transport;GO:0106272//protein localization to ERGIC;GO:0106273//cytosol to ERGIC protein transport;GO:1902003//regulation of amyloid-beta formation;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process"	--
ENSG00000170364	16.27	14.307	15.322	12.653	14.487	11.747	571	467	394	332	414	316	SETMAR	SET domain and mariner transposase fusion gene [Source:HGNC Symbol;Acc:HGNC:10762]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11433;K11433	GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0035861//site of double-strand break	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0002039//p53 binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0042803//protein homodimerization activity;GO:0044547//DNA topoisomerase binding;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0000729//DNA double-strand break processing;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0008283//cell population proliferation;GO:0010452//histone H3-K36 methylation;GO:0015074//DNA integration;GO:0031297//replication fork processing;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0044774//mitotic DNA integrity checkpoint signaling;GO:0051568//histone H3-K4 methylation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0097676//histone H3-K36 dimethylation;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:2001251//negative regulation of chromosome organization"	--
ENSG00000170365	5.656	5.879	5.284	6.452	5.309	5.601	288	320	197	254	256	238	SMAD1	SMAD family member 1 [Source:HGNC Symbol;Acc:HGNC:6767]	Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Cellular community - eukaryotes;Signal transduction	ko05202//Transcriptional misregulation in cancer;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04676;K04676;K04676;K04676	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0071141//SMAD protein complex;GO:0071142//homomeric SMAD protein complex;GO:0071144//heteromeric SMAD protein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0070410//co-SMAD binding;GO:0070411//I-SMAD binding;GO:0070878//primary miRNA binding"	"GO:0000165//MAPK cascade;GO:0001649//osteoblast differentiation;GO:0001657//ureteric bud development;GO:0001710//mesodermal cell fate commitment;GO:0002051//osteoblast fate commitment;GO:0003161//cardiac conduction system development;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007183//SMAD protein complex assembly;GO:0007276//gamete generation;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0009880//embryonic pattern specification;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0031053//primary miRNA processing;GO:0042592//homeostatic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051148//negative regulation of muscle cell differentiation;GO:0051216//cartilage development;GO:0060038//cardiac muscle cell proliferation;GO:0060348//bone development;GO:0060395//SMAD protein signal transduction;GO:0061036//positive regulation of cartilage development;GO:0071407//cellular response to organic cyclic compound;GO:0071773//cellular response to BMP stimulus;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903672//positive regulation of sprouting angiogenesis"	MH1
ENSG00000170367	0	0	0	0	0	0	0	0	0	0	0	0	CST5	cystatin D [Source:HGNC Symbol;Acc:HGNC:2477]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13901	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000170369	0	0	0	0	0	0	0	0	0	0	0	0	CST2	cystatin SA [Source:HGNC Symbol;Acc:HGNC:2474]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13898	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000170370	0.037	0	0	0	0	0.042	2	0	0	0	0	1	EMX2	empty spiracles homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3341]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0009410//response to xenobiotic stimulus;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0021542//dentate gyrus development;GO:0021796//cerebral cortex regionalization;GO:0021846//cell proliferation in forebrain;GO:0021885//forebrain cell migration;GO:0021987//cerebral cortex development;GO:0030182//neuron differentiation;GO:0030900//forebrain development;GO:0072197//ureter morphogenesis"	Homeobox
ENSG00000170373	0	0	0	0	0.305	0	0	0	0	0	4	0	CST1	cystatin SN [Source:HGNC Symbol;Acc:HGNC:2473]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13897	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000170374	0	0	0	0.088	0	0	0	0	0	2	0	0	SP7	Sp7 transcription factor [Source:HGNC Symbol;Acc:HGNC:17321]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0046872//metal ion binding"	GO:0001649//osteoblast differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010467//gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051336//regulation of hydrolase activity;GO:0060218//hematopoietic stem cell differentiation;GO:0071344//diphosphate metabolic process;GO:0071529//cementum mineralization;GO:2000738//positive regulation of stem cell differentiation	zf-C2H2
ENSG00000170379	0.175	0.168	0.166	0.181	0.327	0.074	20	12.36	14	15.33	26.47	5.03	TCAF2	TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0044325//transmembrane transporter binding	GO:0010359//regulation of anion channel activity;GO:0010360//negative regulation of anion channel activity;GO:0030335//positive regulation of cell migration;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000170381	0.968	0.656	0.642	0.945	1.041	0.71	103	77.34	25	71	89	56	SEMA3E	semaphorin 3E [Source:HGNC Symbol;Acc:HGNC:10727]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06840	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001755//neural crest cell migration;GO:0001953//negative regulation of cell-matrix adhesion;GO:0002040//sprouting angiogenesis;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050808//synapse organization;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000170382	41.574	44.674	46.095	39.591	43.954	37.901	2923	3162	2411	2091	2649	1957	LRRN2	leucine rich repeat neuronal 2 [Source:HGNC Symbol;Acc:HGNC:16914]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007155//cell adhesion;GO:0007165//signal transduction	--
ENSG00000170385	17.115	13.869	16.793	13.452	14.961	21.139	2092	1704	1516	1218	1545	1880	SLC30A1	solute carrier family 30 member 1 [Source:HGNC Symbol;Acc:HGNC:11012]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14688	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0031965//nuclear membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0019855//calcium channel inhibitor activity	GO:0001701//in utero embryonic development;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006829//zinc ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0010312//detoxification of zinc ion;GO:0046929//negative regulation of neurotransmitter secretion;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070574//cadmium ion transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071584//negative regulation of zinc ion transmembrane import;GO:0071585//detoxification of cadmium ion;GO:0090281//negative regulation of calcium ion import	--
ENSG00000170390	8.006	8.668	8.611	7.83	7.018	7.549	566	612	412	385	410	368	DCLK2	doublecortin like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19002]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0021766//hippocampus development;GO:0021860//pyramidal neuron development;GO:0035556//intracellular signal transduction;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000170396	5.517	3.994	4.225	3.407	3.668	5.167	518	377	293	237	291	353	ZNF804A	zinc finger protein 804A [Source:HGNC Symbol;Acc:HGNC:21711]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030424//axon;GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0098793//presynapse;GO:0098794//postsynapse;GO:1901588//dendritic microtubule	GO:0003674//molecular_function;GO:0046872//metal ion binding	GO:0010628//positive regulation of gene expression;GO:0010975//regulation of neuron projection development;GO:0010976//positive regulation of neuron projection development;GO:1902952//positive regulation of dendritic spine maintenance	--
ENSG00000170412	90.181	94.575	103.137	107.673	104.382	117.366	3329	3496	2751	2942	3266	3006	GPRC5C	G protein-coupled receptor class C group 5 member C [Source:HGNC Symbol;Acc:HGNC:13309]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032147//activation of protein kinase activity	--
ENSG00000170417	1.859	2.648	1.85	2.275	1.507	1.826	122	150	85	75	78	76	TMEM182	transmembrane protein 182 [Source:HGNC Symbol;Acc:HGNC:26391]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0014906//myotube cell development involved in skeletal muscle regeneration;GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0045662//negative regulation of myoblast differentiation;GO:1901740//negative regulation of myoblast fusion	--
ENSG00000170419	0	0	0	0	0	0	0	0	0	0	0	0	VSTM2A	V-set and transmembrane domain containing 2A [Source:HGNC Symbol;Acc:HGNC:28499]	-	-	-	-	GO:0005576//extracellular region;GO:0016021//integral component of membrane	GO:0042802//identical protein binding	GO:0010628//positive regulation of gene expression;GO:0010884//positive regulation of lipid storage;GO:0030154//cell differentiation;GO:0070352//positive regulation of white fat cell proliferation;GO:0071773//cellular response to BMP stimulus;GO:0090336//positive regulation of brown fat cell differentiation	--
ENSG00000170421	220.855	230.641	169.925	227.84	229.037	196.461	8180	8576.01	4668	6265	7146	5299	KRT8	keratin 8 [Source:HGNC Symbol;Acc:HGNC:6446]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0016363//nuclear matrix;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0097110//scaffold protein binding	GO:0070268//cornification	--
ENSG00000170423	0	0	0	0	0	0	0	0	0	0	0	0	KRT78	keratin 78 [Source:HGNC Symbol;Acc:HGNC:28926]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000170425	7.159	6.208	8.235	6.586	6.186	7.009	226	197	192	154	165	161	ADORA2B	adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Substance dependence;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04015//Rap1 signaling pathway;ko05034//Alcoholism;ko04270//Vascular smooth muscle contraction	K04267;K04267;K04267;K04267;K04267	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0001609//G protein-coupled adenosine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0002882//positive regulation of chronic inflammatory response to non-antigenic stimulus;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010753//positive regulation of cGMP-mediated signaling;GO:0031284//positive regulation of guanylate cyclase activity;GO:0031668//cellular response to extracellular stimulus;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0043306//positive regulation of mast cell degranulation;GO:0060087//relaxation of vascular associated smooth muscle;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000170426	0	0	0	0	0	0	0	0	0	0	0	0	SDR9C7	short chain dehydrogenase/reductase family 9C member 7 [Source:HGNC Symbol;Acc:HGNC:29958]	-	-	-	-	GO:0005737//cytoplasm	GO:0004745//NAD-retinol dehydrogenase activity;GO:0016491//oxidoreductase activity	-	--
ENSG00000170430	7.836	8.787	10.106	11.897	9.22	9.94	207	236	200	234	210	194	MGMT	O-6-methylguanine-DNA methyltransferase [Source:HGNC Symbol;Acc:HGNC:7059]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane	GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0003908//methylated-DNA-[protein]-cysteine S-methyltransferase activity;GO:0005509//calcium ion binding;GO:0008168//methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006266//DNA ligation;GO:0006281//DNA repair;GO:0006306//DNA methylation;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0014070//response to organic cyclic compound;GO:0032259//methylation;GO:0034599//cellular response to oxidative stress;GO:0043066//negative regulation of apoptotic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045471//response to ethanol;GO:0045739//positive regulation of DNA repair;GO:0051593//response to folic acid;GO:0060548//negative regulation of cell death;GO:0060644//mammary gland epithelial cell differentiation;GO:0071407//cellular response to organic cyclic compound;GO:0071479//cellular response to ionizing radiation;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000170439	1.062	1.093	1.587	1.385	1.214	1.309	29	30	32	28	28	26	METTL7B	methyltransferase like 7B [Source:HGNC Symbol;Acc:HGNC:28276]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane	GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0018708//thiol S-methyltransferase activity	GO:0032259//methylation	--
ENSG00000170442	0.133	0.226	0.062	0	0.082	0.095	5.78	9.85	2	0	3	3	KRT86	keratin 86 [Source:HGNC Symbol;Acc:HGNC:6463]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000170445	29.519	31.969	31.419	30.418	28.511	31.482	1196.42	1312.9	948.9	914.8	987.73	933.27	HARS1	histidyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:4816]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01892	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004821//histidine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006427//histidyl-tRNA aminoacylation;GO:0032543//mitochondrial translation;GO:0034645//cellular macromolecule biosynthetic process;GO:0044238//primary metabolic process	--
ENSG00000170448	2.444	1.799	2.1	1.17	1.504	2.34	189	141	121	67	99	132	NFXL1	"nuclear transcription factor, X-box binding like 1 [Source:HGNC Symbol;Acc:HGNC:18726]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-NF-X1
ENSG00000170454	0	0	0	0	0	0	0	0	0	0	0	0	KRT75	keratin 75 [Source:HGNC Symbol;Acc:HGNC:24431]	-	-	-	-	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000170456	10.391	9.426	8.783	6.848	8.092	9.377	1877	1595	1119	889	1167	1145	DENND5B	DENN domain containing 5B [Source:HGNC Symbol;Acc:HGNC:28338]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0050790//regulation of catalytic activity;GO:1905885//positive regulation of triglyceride transport	--
ENSG00000170458	0.036	0	0.048	0	0.219	0.098	1	0	1	0	6	2	CD14	CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cardiovascular disease;Signal transduction;Infectious disease: parasitic;Immune system;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial;Cancer: specific types;Infectious disease: bacterial	ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko04936//Alcoholic liver disease;ko04620//Toll-like receptor signaling pathway;ko05133//Pertussis;ko05221//Acute myeloid leukemia;ko05134//Legionellosis	K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391;K04391	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0045121//membrane raft;GO:0046696//lipopolysaccharide receptor complex;GO:0070062//extracellular exosome	GO:0001530//lipopolysaccharide binding;GO:0001847//opsonin receptor activity;GO:0005515//protein binding;GO:0016019//peptidoglycan immune receptor activity;GO:0070891//lipoteichoic acid binding;GO:0071723//lipopeptide binding	GO:0001819//positive regulation of cytokine production;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0006898//receptor-mediated endocytosis;GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0009408//response to heat;GO:0009617//response to bacterium;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032026//response to magnesium ion;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0032729//positive regulation of interferon-gamma production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034612//response to tumor necrosis factor;GO:0045087//innate immune response;GO:0045471//response to ethanol;GO:0045807//positive regulation of endocytosis;GO:0051602//response to electrical stimulus;GO:0071219//cellular response to molecule of bacterial origin;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000170464	12.995	8.872	10.041	10.116	8.609	9.364	823	856	600	607	656	654	DNAJC18	DnaJ heat shock protein family (Hsp40) member C18 [Source:HGNC Symbol;Acc:HGNC:28429]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030544//Hsp70 protein binding	GO:0030433//ubiquitin-dependent ERAD pathway;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein	--
ENSG00000170465	0	0	0	0	0	0	0	0	0	0	0	0	KRT6C	keratin 6C [Source:HGNC Symbol;Acc:HGNC:20406]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000170468	3.877	5.104	5.276	4.97	4.473	5.786	198	262	199	188	193	215	RIOX1	ribosomal oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:20968]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0034647//histone H3-tri/di/monomethyl-lysine-4 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140680//histone H3-di/monomethyl-lysine-36 demethylase activity	"GO:0006325//chromatin organization;GO:0034720//histone H3-K4 demethylation;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation"	--
ENSG00000170469	1.389	1.74	1.045	0.897	0.91	1.503	19	24	11	9	11	15	SPATA24	spermatogenesis associated 24 [Source:HGNC Symbol;Acc:HGNC:27322]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000170471	13.664	13.276	13.129	10.682	11.979	12.546	2183	2140	1672	1320	1651	1547	RALGAPB	Ral GTPase activating protein non-catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:29221]	-	-	-	-	-	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000170473	6.563	5.83	8.716	7.612	7.548	7.021	154	129	150	128	149	117	PYM1	"PYM homolog 1, exon junction complex associated factor [Source:HGNC Symbol;Acc:HGNC:30258]"	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14294;K14294	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0035145//exon-exon junction complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043022//ribosome binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006417//regulation of translation;GO:0045727//positive regulation of translation;GO:1903259//exon-exon junction complex disassembly"	--
ENSG00000170476	0	0	0	0	0.123	0	0	0	0	0	2	0	MZB1	marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0034663//endoplasmic reticulum chaperone complex	GO:0005515//protein binding	GO:0002639//positive regulation of immunoglobulin production;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell population proliferation;GO:0030888//regulation of B cell proliferation;GO:0033622//integrin activation;GO:0042127//regulation of cell population proliferation;GO:0046626//regulation of insulin receptor signaling pathway	--
ENSG00000170477	0.026	0.09	0.035	0.035	0.062	0	1	4	1	1	2	0	KRT4	keratin 4 [Source:HGNC Symbol;Acc:HGNC:6441]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0009986//cell surface;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton	GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0030855//epithelial cell differentiation;GO:0050680//negative regulation of epithelial cell proliferation	--
ENSG00000170482	0.126	0.042	0	0	0.075	0.029	6	2	0	0	3	1	SLC23A1	solute carrier family 23 member 1 [Source:HGNC Symbol;Acc:HGNC:10974]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14611	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043229//intracellular organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008520//L-ascorbate:sodium symporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015205//nucleobase transmembrane transporter activity;GO:0015229//L-ascorbic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007420//brain development;GO:0009636//response to toxic substance;GO:0015851//nucleobase transport;GO:0015882//L-ascorbic acid transmembrane transport;GO:0019852//L-ascorbic acid metabolic process;GO:0030324//lung development;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:0070904//transepithelial L-ascorbic acid transport	--
ENSG00000170484	0	0	0	0	0	0	0	0	0	0	0	0	KRT74	keratin 74 [Source:HGNC Symbol;Acc:HGNC:28929]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:1990254//keratin filament binding	GO:0045104//intermediate filament cytoskeleton organization;GO:0070268//cornification	--
ENSG00000170485	10.714	9.336	10.712	11.899	11.576	12.63	655	643	476	502	646	554	NPAS2	neuronal PAS domain protein 2 [Source:HGNC Symbol;Acc:HGNC:7895]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K09026	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990513//CLOCK-BMAL transcription complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007417//central nervous system development;GO:0009410//response to xenobiotic stimulus;GO:0032922//circadian regulation of gene expression;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0051775//response to redox state;GO:0060548//negative regulation of cell death;GO:2000987//positive regulation of behavioral fear response;GO:2001020//regulation of response to DNA damage stimulus"	bHLH
ENSG00000170486	0	0	0	0	0	0	0	0	0	0	0	0	KRT72	keratin 72 [Source:HGNC Symbol;Acc:HGNC:28932]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000170498	0	0	0.091	0	0	0	0	0	1	0	0	0	KISS1	KiSS-1 metastasis suppressor [Source:HGNC Symbol;Acc:HGNC:6341]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04929//GnRH secretion	K23140;K23140	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0005515//protein binding;GO:0031773//kisspeptin receptor binding	GO:0007010//cytoskeleton organization;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008285//negative regulation of cell population proliferation;GO:0033686//positive regulation of luteinizing hormone secretion;GO:0043410//positive regulation of MAPK cascade;GO:0050806//positive regulation of synaptic transmission;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060112//generation of ovulation cycle rhythm;GO:0060124//positive regulation of growth hormone secretion	--
ENSG00000170500	0.811	0.98	1.395	1.415	1.509	1.386	254	268	219	238	280	243	LONRF2	LON peptidase N-terminal domain and ring finger 2 [Source:HGNC Symbol;Acc:HGNC:24788]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000170502	26.103	26.064	32.453	26.679	31.786	47.873	1393	1232	1115	981	1216	1464	NUDT9	nudix hydrolase 9 [Source:HGNC Symbol;Acc:HGNC:8056]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13988;K13988	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0047631//ADP-ribose diphosphatase activity	GO:0046032//ADP catabolic process;GO:0046709//IDP catabolic process;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000170509	0	0	0	0	0.075	0	0	0	0	0	3	0	HSD17B13	hydroxysteroid 17-beta dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:18685]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol	"GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0046889//positive regulation of lipid biosynthetic process	--
ENSG00000170515	45.899	48.686	53.759	52.253	50.22	45.057	1736	1761	1419	1429	1508	1276.75	PA2G4	proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	"GO:0006364//rRNA processing;GO:0006417//regulation of translation;GO:0043066//negative regulation of apoptotic process;GO:0045597//positive regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000170516	0	0	0	0	0	0	0	0	0	0	0	0	COX7B2	cytochrome c oxidase subunit 7B2 [Source:HGNC Symbol;Acc:HGNC:24381]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271;K02271	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045277//respiratory chain complex IV	GO:0004129//cytochrome-c oxidase activity	GO:0006119//oxidative phosphorylation;GO:0022900//electron transport chain;GO:1902600//proton transmembrane transport	--
ENSG00000170522	3.128	3.114	2.206	2.665	2.106	2.22	334	275	222	174	242	219	ELOVL6	ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10203;K10203;K10203;K10203	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0009923//fatty acid elongase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity"	"GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000170523	0	0	0	0	0	0	0	0	0	0	0	0	KRT83	keratin 83 [Source:HGNC Symbol;Acc:HGNC:6460]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	GO:0007568//aging;GO:0008544//epidermis development;GO:0042633//hair cycle	--
ENSG00000170525	6.66	6.302	4.6	5.565	6.32	6.052	484	473	294	323	445	333	PFKFB3	"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC Symbol;Acc:HGNC:8874]"	Metabolism;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko00051//Fructose and mannose metabolism	K01103;K01103;K01103;K01103	GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003873//6-phosphofructo-2-kinase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity"	"GO:0006000//fructose metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0007420//brain development;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0016311//dephosphorylation;GO:0046835//carbohydrate phosphorylation"	--
ENSG00000170537	0.521	0.456	0.445	0.192	0.363	0.331	35	38	30	13	28	22	TMC7	transmembrane channel like 7 [Source:HGNC Symbol;Acc:HGNC:23000]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport	--
ENSG00000170540	183.052	171.243	179.871	169.113	163.507	173.955	8649.27	8128.09	6277.01	5916.71	6527.14	5968	ARL6IP1	ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005784//Sec61 translocon complex;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002038//positive regulation of L-glutamate import across plasma membrane;GO:0006613//cotranslational protein targeting to membrane;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071787//endoplasmic reticulum tubular network formation;GO:1903371//regulation of endoplasmic reticulum tubular network organization;GO:1990809//endoplasmic reticulum tubular network membrane organization	--
ENSG00000170542	4.946	5.264	3.718	6.647	6.363	5.502	425	454.65	236	423.12	462	344	SERPINB9	serpin family B member 9 [Source:HGNC Symbol;Acc:HGNC:8955]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0002448//mast cell mediated immunity;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071391//cellular response to estrogen stimulus	--
ENSG00000170545	0.589	0.692	0.474	0.208	0.591	1.096	10	10	5	6	12	15	SMAGP	small cell adhesion glycoprotein [Source:HGNC Symbol;Acc:HGNC:26918]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	-	--
ENSG00000170549	0	0.046	0.094	0	0	0.032	0	2	3	0	0	1	IRX1	iroquois homeobox 1 [Source:HGNC Symbol;Acc:HGNC:14358]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030182//neuron differentiation;GO:0048468//cell development;GO:0072086//specification of loop of Henle identity;GO:0072272//proximal/distal pattern formation involved in metanephric nephron development"	Homeobox
ENSG00000170558	47.161	45.963	30.449	31.944	38.137	34.572	3404	3380	1630	1713	2348	1835	CDH2	cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759]	Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Cardiovascular disease	ko04514//Cell adhesion molecules;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06736;K06736	GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005916//fascia adherens;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0016342//catenin complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0042383//sarcolemma;GO:0043005//neuron projection;GO:0044853//plasma membrane raft;GO:0045177//apical part of cell;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0099059//integral component of presynaptic active zone membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0045294//alpha-catenin binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	"GO:0003323//type B pancreatic cell development;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007416//synapse assembly;GO:0007420//brain development;GO:0009966//regulation of signal transduction;GO:0010001//glial cell differentiation;GO:0014032//neural crest cell development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021987//cerebral cortex development;GO:0034332//adherens junction organization;GO:0035995//detection of muscle stretch;GO:0043410//positive regulation of MAPK cascade;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0048514//blood vessel morphogenesis;GO:0048854//brain morphogenesis;GO:0048872//homeostasis of number of cells;GO:0050770//regulation of axonogenesis;GO:0051146//striated muscle cell differentiation;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060019//radial glial cell differentiation;GO:0060563//neuroepithelial cell differentiation;GO:0070445//regulation of oligodendrocyte progenitor proliferation;GO:0072659//protein localization to plasma membrane;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090497//mesenchymal cell migration;GO:0097118//neuroligin clustering involved in postsynaptic membrane assembly;GO:0097150//neuronal stem cell population maintenance;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1902897//regulation of postsynaptic density protein 95 clustering;GO:2000809//positive regulation of synaptic vesicle clustering"	--
ENSG00000170561	0.908	0.941	1	1.01	1.351	1.396	58	55	44	47	68	62	IRX2	iroquois homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14359]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030182//neuron differentiation;GO:0048468//cell development;GO:0072086//specification of loop of Henle identity;GO:0072272//proximal/distal pattern formation involved in metanephric nephron development"	Homeobox
ENSG00000170571	4.295	2.762	2.022	2.605	3.407	2.711	323	242	115	138	163	145	EMB	embigin [Source:HGNC Symbol;Acc:HGNC:30465]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0045202//synapse	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411//axon guidance;GO:0035879//plasma membrane lactate transport;GO:0070593//dendrite self-avoidance	--
ENSG00000170577	0.022	0	0.059	0	0.026	0	1	0	2	0	1	0	SIX2	SIX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:10888]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001656//metanephros development;GO:0001822//kidney development;GO:0002062//chondrocyte differentiation;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0007501//mesodermal cell fate specification;GO:0008283//cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0016477//cell migration;GO:0030278//regulation of ossification;GO:0032330//regulation of chondrocyte differentiation;GO:0042474//middle ear morphogenesis;GO:0045596//negative regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048557//embryonic digestive tract morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0072006//nephron development;GO:0072028//nephron morphogenesis;GO:0072038//mesenchymal stem cell maintenance involved in nephron morphogenesis;GO:0072137//condensed mesenchymal cell proliferation;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0090189//regulation of branching involved in ureteric bud morphogenesis;GO:0097168//mesenchymal stem cell proliferation;GO:1902732//positive regulation of chondrocyte proliferation"	Homeobox
ENSG00000170579	0.755	1.23	1.433	0.673	0.591	0.801	91	119	70	58	48	43	DLGAP1	DLG associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2905]	Organismal Systems	Nervous system	ko04724//Glutamatergic synapse	K15008	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0099572//postsynaptic specialization	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0060090//molecular adaptor activity	GO:0007268//chemical synaptic transmission;GO:0023052//signaling;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000170581	19.893	20.587	22.21	19.455	20.912	20.06	1579	1688	1332	1173	1399	1171	STAT2	signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04625//C-type lectin receptor signaling pathway	K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221;K11221	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070721//ISGF3 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding"	"GO:0001932//regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0019221//cytokine-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0090140//regulation of mitochondrial fission"	STAT
ENSG00000170584	1.894	4.547	2.319	2.394	1.662	4.002	313	310	283	293	232	218	NUDCD2	NudC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30535]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle"	GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding	--
ENSG00000170604	13.737	14.291	14.941	17.748	16.124	16.761	722	755	580	691	716	641	IRF2BP1	interferon regulatory factor 2 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21728]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000170605	0	0	0	0	0	0	0	0	0	0	0	0	OR9K2	olfactory receptor family 9 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:15339]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170606	34.679	30.814	30.177	22.618	23.106	27.245	3434	3067	2207	1659	1933	1963	HSPA4	heat shock protein family A (Hsp70) member 4 [Source:HGNC Symbol;Acc:HGNC:5237]	Human Diseases;Cellular Processes;Organismal Systems	Cardiovascular disease;Cellular community - eukaryotes;Immune system	ko05417//Lipid and atherosclerosis;ko04530//Tight junction;ko04612//Antigen processing and presentation	K09489;K09489;K09489	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0006986//response to unfolded protein;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0051131//chaperone-mediated protein complex assembly	--
ENSG00000170608	0.297	0	0	0	0.148	0.103	7	0	0	0	5	3	FOXA3	forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08038	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001678//cellular glucose homeostasis;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0009267//cellular response to starvation;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0061484//hematopoietic stem cell homeostasis"	Fork_head
ENSG00000170613	0	0	0	0	0	0	0	0	0	0	0	0	FAM71B	family with sequence similarity 71 member B [Source:HGNC Symbol;Acc:HGNC:28397]	-	-	-	-	GO:0005634//nucleus;GO:0005794//Golgi apparatus	-	-	--
ENSG00000170615	0	0	0	0	0	0	0	0	0	0	0	0	SLC26A5	solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0120249//lateral wall of outer hair cell	GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0030507//spectrin binding;GO:0042802//identical protein binding	GO:0002931//response to ischemia;GO:0007605//sensory perception of sound;GO:0008272//sulfate transport;GO:0008360//regulation of cell shape;GO:0009410//response to xenobiotic stimulus;GO:0009751//response to salicylic acid;GO:0010996//response to auditory stimulus;GO:0015701//bicarbonate transport;GO:0015755//fructose transmembrane transport;GO:0019532//oxalate transport;GO:0034220//ion transmembrane transport;GO:0034766//negative regulation of ion transmembrane transport;GO:0035864//response to potassium ion;GO:0042391//regulation of membrane potential;GO:0045793//positive regulation of cell size;GO:0055085//transmembrane transport;GO:0090102//cochlea development;GO:0097066//response to thyroid hormone;GO:0098656//anion transmembrane transport;GO:1902074//response to salt;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport;GO:2000147//positive regulation of cell motility	--
ENSG00000170619	10.468	12.358	13.847	15.591	13.343	14.23	299.28	358	289.27	317.59	331.02	290.79	COMMD5	COMM domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17902]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000170624	1.538	1.341	0.982	1.833	1.491	2.635	166	174	114	162	204	225	SGCD	sarcoglycan delta [Source:HGNC Symbol;Acc:HGNC:10807]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K12563;K12563;K12563;K12563	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016011//dystroglycan complex;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0042383//sarcolemma	-	GO:0003015//heart process;GO:0007517//muscle organ development;GO:0019722//calcium-mediated signaling;GO:0031503//protein-containing complex localization;GO:0048738//cardiac muscle tissue development;GO:0055013//cardiac muscle cell development;GO:0055074//calcium ion homeostasis;GO:0060047//heart contraction;GO:0060048//cardiac muscle contraction;GO:0060977//coronary vasculature morphogenesis;GO:0086003//cardiac muscle cell contraction	--
ENSG00000170627	0	0	0	0	0	0	0	0	0	0	0	0	GTSF1	gametocyte specific factor 1 [Source:HGNC Symbol;Acc:HGNC:26565]	-	-	-	-	GO:0005737//cytoplasm	GO:0046872//metal ion binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000170631	4.626	4.951	4.079	4.908	3.869	4.198	242	239	141	156	171	145	ZNF16	zinc finger protein 16 [Source:HGNC Symbol;Acc:HGNC:12947]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0033674//positive regulation of kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0051301//cell division;GO:0051781//positive regulation of cell division;GO:0072707//cellular response to sodium dodecyl sulfate;GO:1901989//positive regulation of cell cycle phase transition	zf-C2H2
ENSG00000170632	23.236	24.657	20.783	23.618	22.033	19.042	1120	1130	755	824	834	665	ARMC10	armadillo repeat containing 10 [Source:HGNC Symbol;Acc:HGNC:21706]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0050692//DNA binding domain binding	GO:0040008//regulation of growth;GO:0040010//positive regulation of growth rate;GO:0043066//negative regulation of apoptotic process;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000170633	8.449	10.013	12.215	11.473	10.476	14.587	348.05	414.19	335	349.07	365	372	RNF34	ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016607//nuclear speck	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:1901981//phosphatidylinositol phosphate binding	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070417//cellular response to cold;GO:0070936//protein K48-linked ubiquitination;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000374//regulation of oxygen metabolic process;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis"	--
ENSG00000170634	8.512	7.687	8.673	9.815	9.189	10.844	182	168	143	149	169	170	ACYP2	acylphosphatase 2 [Source:HGNC Symbol;Acc:HGNC:180]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K01512;K01512	-	GO:0003998//acylphosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006796//phosphate-containing compound metabolic process	--
ENSG00000170638	5.789	6.034	6.276	6.266	6.388	7.136	272	278	220	219	253	245	TRABD	TraB domain containing [Source:HGNC Symbol;Acc:HGNC:28805]	-	-	-	-	-	-	-	--
ENSG00000170653	13.035	10.861	12.951	12.978	14.23	13.362	1455	1463	1191	1124	1378	1133	ATF7	activating transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:792]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex"	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0035497//cAMP response element binding;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000170667	1.156	0.977	0.761	0.821	1.092	0.705	108	91.54	46.75	56.13	94.59	49.59	RASA4B	RAS p21 protein activator 4B [Source:HGNC Symbol;Acc:HGNC:35202]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17630	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding	GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0071277//cellular response to calcium ion	--
ENSG00000170677	7.044	6.294	5.088	4.316	6.38	6.658	654	576	376	330	387	407	SOCS6	suppressor of cytokine signaling 6 [Source:HGNC Symbol;Acc:HGNC:16833]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K04699;K04699	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex	GO:0005515//protein binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0006952//defense response;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009968//negative regulation of signal transduction;GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0050868//negative regulation of T cell activation	--
ENSG00000170681	1.618	1.393	0.969	1.45	1.289	1.433	104	90	46	69	70	67	CAVIN4	caveolae associated protein 4 [Source:HGNC Symbol;Acc:HGNC:33742]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0007517//muscle organ development;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0035023//regulation of Rho protein signal transduction;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000170683	0	0	0	0	0	0	0	0	0	0	0	0	OR10A3	olfactory receptor family 10 subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:8162]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170684	0.325	0.499	0.36	0.717	0.454	0.487	11	17	9	18	13	12	ZNF296	zinc finger protein 296 [Source:HGNC Symbol;Acc:HGNC:15981]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000170689	0.037	0.13	0	0	0.154	0.051	2	7	0	0	7	2	HOXB9	homeobox B9 [Source:HGNC Symbol;Acc:HGNC:5120]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0030879//mammary gland development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0060326//cell chemotaxis"	Homeobox
ENSG00000170703	0.154	0.26	1.102	0.321	0.237	0.675	9	15	18	17	12	18	TTLL6	tubulin tyrosine ligase like 6 [Source:HGNC Symbol;Acc:HGNC:26664]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097731//9+0 non-motile cilium	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070739//protein-glutamic acid ligase activity;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0003353//positive regulation of cilium movement;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation;GO:0051013//microtubule severing;GO:0060296//regulation of cilium beat frequency involved in ciliary motility	--
ENSG00000170734	3.928	5.397	4.732	3.555	4.471	3.446	438	539	350	278	383	296	POLH	DNA polymerase eta [Source:HGNC Symbol;Acc:HGNC:9181]	Human Diseases;Genetic Information Processing	Drug resistance: antineoplastic;Replication and repair	ko01524//Platinum drug resistance;ko03460//Fanconi anemia pathway	K03509;K03509	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005829//cytosol;GO:0035861//site of double-strand break	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006290//pyrimidine dimer repair;GO:0006301//postreplication repair;GO:0006974//cellular response to DNA damage stimulus;GO:0009314//response to radiation;GO:0010225//response to UV-C;GO:0042276//error-prone translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0071494//cellular response to UV-C;GO:0071897//DNA biosynthetic process	--
ENSG00000170743	3.783	4.087	3.458	3.22	3.596	2.748	314	341	212	198	250	166	SYT9	synaptotagmin 9 [Source:HGNC Symbol;Acc:HGNC:19265]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0030285//integral component of synaptic vesicle membrane;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0070382//exocytic vesicle;GO:0098686//hippocampal mossy fiber to CA3 synapse	"GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0050796//regulation of insulin secretion;GO:0071277//cellular response to calcium ion;GO:0099502//calcium-dependent activation of synaptic vesicle fusion	--
ENSG00000170745	7.229	6.488	9.76	8.786	9.068	11.788	351	317	350	316	372	417	KCNS3	potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000170748	0	0.111	0	0	0	0.031	0	5	0	0	0	1	RBMXL2	RBMX like 2 [Source:HGNC Symbol;Acc:HGNC:17886]	-	-	-	-	GO:0005634//nucleus;GO:0005689//U12-type spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0017069//snRNA binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000170759	18.566	13.402	11.484	8.799	10.234	11.601	2259	1639	1032	793	1052	1027	KIF5B	kinesin family member 5B [Source:HGNC Symbol;Acc:HGNC:6324]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Nervous system;Cancer: specific types	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection;ko04144//Endocytosis;ko04728//Dopaminergic synapse;ko05223//Non-small cell lung cancer	K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396;K10396	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0031982//vesicle;GO:0032839//dendrite cytoplasm;GO:0034451//centriolar satellite;GO:0035253//ciliary rootlet;GO:0043005//neuron projection;GO:0043227//membrane-bounded organelle;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding	"GO:0007018//microtubule-based movement;GO:0007028//cytoplasm organization;GO:0007411//axon guidance;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032418//lysosome localization;GO:0035617//stress granule disassembly;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042391//regulation of membrane potential;GO:0043268//positive regulation of potassium ion transport;GO:0047496//vesicle transport along microtubule;GO:0048489//synaptic vesicle transport;GO:0051642//centrosome localization;GO:0071346//cellular response to interferon-gamma;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex;GO:0099641//anterograde axonal protein transport;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1990048//anterograde neuronal dense core vesicle transport;GO:1990049//retrograde neuronal dense core vesicle transport"	--
ENSG00000170775	0.728	0.706	0.271	0.885	0.539	0.725	80	78	22	72	50	58	GPR37	G protein-coupled receptor 37 [Source:HGNC Symbol;Acc:HGNC:4494]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K04243;K04243	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0030165//PDZ domain binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0036505//prosaposin receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0016358//dendrite development;GO:0031987//locomotion involved in locomotory behavior;GO:0042416//dopamine biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0045964//positive regulation of dopamine metabolic process;GO:1903206//negative regulation of hydrogen peroxide-induced cell death	--
ENSG00000170776	7.683	7.365	6.13	5.868	7.708	6.611	1827	1728	1023	1065	1357	1042	AKAP13	A-kinase anchoring protein 13 [Source:HGNC Symbol;Acc:HGNC:371]	Human Diseases;Organismal Systems	Infectious disease: viral;Endocrine system	"ko05163//Human cytomegalovirus infection;ko04928//Parathyroid hormone synthesis, secretion and action"	K16529;K16529	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030864//cortical actin cytoskeleton;GO:0110165//cellular anatomical entity	GO:0004691//cAMP-dependent protein kinase activity;GO:0005078//MAP-kinase scaffold activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0051018//protein kinase A binding;GO:0060090//molecular adaptor activity	GO:0006468//protein phosphorylation;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007507//heart development;GO:0035023//regulation of Rho protein signal transduction;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0055007//cardiac muscle cell differentiation;GO:0060297//regulation of sarcomere organization;GO:0060348//bone development;GO:0071875//adrenergic receptor signaling pathway;GO:0086023//adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	--
ENSG00000170777	0	0	0	0	0	0	0	0	0	0	0	0	TPD52L3	TPD52 like 3 [Source:HGNC Symbol;Acc:HGNC:23382]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000170779	3.19	3.623	2.507	2.712	2.867	3.302	162	183	94	102	123	122	CDCA4	cell division cycle associated 4 [Source:HGNC Symbol;Acc:HGNC:14625]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0051301//cell division	--
ENSG00000170782	0	0	0	0	0	0	0	0	0	0	0	0	OR10A4	olfactory receptor family 10 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:15130]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007411//axon guidance;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170786	0	0.04	0	0	0.024	0	0	2	0	0	1	0	SDR16C5	short chain dehydrogenase/reductase family 16C member 5 [Source:HGNC Symbol;Acc:HGNC:30311]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K15734;K15734	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017053//transcription repressor complex	"GO:0003714//transcription corepressor activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0031065//positive regulation of histone deacetylation;GO:0035067//negative regulation of histone acetylation;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0043616//keratinocyte proliferation	--
ENSG00000170788	0	0.064	0	0	0	0	0	1	0	0	0	0	DYDC1	DPY30 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23460]	-	-	-	-	GO:0005634//nucleus;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex	GO:0005515//protein binding	GO:0051568//histone H3-K4 methylation	--
ENSG00000170790	0	0	0	0	0	0	0	0	0	0	0	0	OR10A2	olfactory receptor family 10 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8161]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170791	12.406	13.215	14.424	11.775	12.364	16.181	382	395	284	268	294	298	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000170801	0.271	0.233	0.283	0.385	0.401	0.13	14	11	11	15	17	5	HTRA3	HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406]	-	-	-	-	GO:0005576//extracellular region	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway	--
ENSG00000170802	2.75	2.022	1.835	1.674	1.823	2.286	267	186	144	106	133	155	FOXN2	forkhead box N2 [Source:HGNC Symbol;Acc:HGNC:5281]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035914//skeletal muscle cell differentiation"	Fork_head
ENSG00000170807	0	0	0	0	0	0	0	0	0	0	0	0	LMOD2	leiomodin 2 [Source:HGNC Symbol;Acc:HGNC:6648]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0031430//M band	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005523//tropomyosin binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0030041//actin filament polymerization;GO:0030239//myofibril assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0045010//actin nucleation;GO:0045214//sarcomere organization;GO:0051694//pointed-end actin filament capping	--
ENSG00000170819	0.415	0.761	0.518	1.421	1.17	1.315	13	24	12	33	31	30	BFSP2	beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0007601//visual perception;GO:0045104//intermediate filament cytoskeleton organization;GO:0045109//intermediate filament organization;GO:0048469//cell maturation;GO:0050896//response to stimulus;GO:0070307//lens fiber cell development	--
ENSG00000170820	0.108	0.069	0.255	0.09	0.153	0	2	4	7	3	3	0	FSHR	follicle stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:3969]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04913//Ovarian steroidogenesis	K04247;K04247;K04247	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0110165//cellular anatomical entity	GO:0004930//G protein-coupled receptor activity;GO:0004963//follicle-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity;GO:0017046//peptide hormone binding	"GO:0001541//ovarian follicle development;GO:0001545//primary ovarian follicle growth;GO:0001932//regulation of protein phosphorylation;GO:0003073//regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0007292//female gamete generation;GO:0007626//locomotory behavior;GO:0008406//gonad development;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0009992//cellular water homeostasis;GO:0010640//regulation of platelet-derived growth factor receptor signaling pathway;GO:0010738//regulation of protein kinase A signaling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0022602//ovulation cycle process;GO:0031175//neuron projection development;GO:0032350//regulation of hormone metabolic process;GO:0033044//regulation of chromosome organization;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0035092//sperm chromatin condensation;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0045056//transcytosis;GO:0045670//regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:0050896//response to stimulus;GO:0060009//Sertoli cell development;GO:0060011//Sertoli cell proliferation;GO:0060065//uterus development;GO:0060408//regulation of acetylcholine metabolic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071711//basement membrane organization"	--
ENSG00000170832	32.587	29.353	33.344	26.766	26.594	30.052	3257	2700	2269	1644.99	2168	1978	USP32	ubiquitin specific peptidase 32 [Source:HGNC Symbol;Acc:HGNC:19143]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000170835	0.162	0.282	0.274	0.328	0.407	0.334	8	14	10	12	17	12	CEL	carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848]	Metabolism;Organismal Systems;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Lipid metabolism;Digestive system;Lipid metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption;ko00100//Steroid biosynthesis	K12298;K12298;K12298;K12298;K12298	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0099060//integral component of postsynaptic specialization membrane	"GO:0003824//catalytic activity;GO:0004771//sterol esterase activity;GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0008126//acetylesterase activity;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0052689//carboxylic ester hydrolase activity"	GO:0006629//lipid metabolic process;GO:0006707//cholesterol catabolic process;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0009062//fatty acid catabolic process;GO:0016042//lipid catabolic process;GO:0018350//protein esterification;GO:0030157//pancreatic juice secretion;GO:0030299//intestinal cholesterol absorption;GO:0044258//intestinal lipid catabolic process;GO:0046514//ceramide catabolic process;GO:0048488//synaptic vesicle endocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly	--
ENSG00000170836	6.437	6.113	6.22	5.903	5.059	8.23	454	452	292	321	330	390	PPM1D	"protein phosphatase, Mg2+/Mn2+ dependent 1D [Source:HGNC Symbol;Acc:HGNC:9277]"	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10147	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004674//protein serine/threonine kinase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006306//DNA methylation;GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0009314//response to radiation;GO:0009617//response to bacterium;GO:0016311//dephosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0031507//heterochromatin assembly;GO:0035970//peptidyl-threonine dephosphorylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0060260//regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000170837	1.588	1.507	2.199	3.745	2.441	1.856	87	83	89	152	113	74	GPR27	G protein-coupled receptor 27 [Source:HGNC Symbol;Acc:HGNC:4482]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1900738//positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	--
ENSG00000170846	5.975	5.964	6.435	6.874	5.89	6.349	244	234	185	194	201	187	--	"novel protein, similar to Morf4 family associated protein 1"	-	-	-	-	-	GO:0005515//protein binding	GO:0051726//regulation of cell cycle	--
ENSG00000170848	0	0	0	0	0	0	0	0	0	0	0	0	PSG6	pregnancy specific beta-1-glycoprotein 6 [Source:HGNC Symbol;Acc:HGNC:9523]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function	GO:0007565//female pregnancy	--
ENSG00000170852	10.08	9.552	8.793	7.793	8.367	9.384	700	711	486	432	529	511	KBTBD2	kelch repeat and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21751]	-	-	-	-	-	GO:0005515//protein binding	GO:0006006//glucose metabolic process;GO:0006629//lipid metabolic process;GO:0010467//gene expression;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0032868//response to insulin	--
ENSG00000170854	8.634	6.656	6.639	7.162	6.26	8.806	449.98	401.6	327.19	325.83	321.23	396.64	RIOX2	ribosomal oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:19441]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0003714//transcription corepressor activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0032452//histone demethylase activity;GO:0032453//histone H3-methyl-lysine-4 demethylase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity	"GO:0034720//histone H3-K4 demethylation;GO:0042254//ribosome biogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation"	--
ENSG00000170855	5.697	6.834	6.919	6.107	6.346	7.081	136	164	122	108	128	123	TRIAP1	TP53 regulated inhibitor of apoptosis 1 [Source:HGNC Symbol;Acc:HGNC:26937]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0032991//protein-containing complex	GO:0002039//p53 binding;GO:0005515//protein binding;GO:1990050//phosphatidic acid transfer activity	"GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0015914//phospholipid transport;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0034644//cellular response to UV;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097035//regulation of membrane lipid distribution;GO:0120009//intermembrane lipid transfer;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2001140//positive regulation of phospholipid transport"	--
ENSG00000170860	4.823	4.998	4.353	4.592	4.145	4.991	336	350	224	237	244	253	LSM3	"LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17874]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12622;K12622	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005829//cytosol;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0120115//Lsm2-8 complex;GO:1990726//Lsm1-7-Pat1 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030629//U6 snRNA 3'-end binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0033962//P-body assembly"	--
ENSG00000170871	10.137	8.935	9.063	5.913	6.301	10.128	1600	1298	968	706	858	936	KIAA0232	KIAA0232 [Source:HGNC Symbol;Acc:HGNC:28992]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000170873	48.875	48.862	57.818	49.259	51.808	55.745	3751	3564	3049.75	2680	3101	2879	MTSS1	MTSS I-BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20443]	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030139//endocytic vesicle;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding	GO:0007009//plasma membrane organization;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030035//microspike assembly;GO:0030036//actin cytoskeleton organization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0034334//adherens junction maintenance;GO:0050680//negative regulation of epithelial cell proliferation;GO:0061333//renal tubule morphogenesis;GO:0071498//cellular response to fluid shear stress;GO:0072102//glomerulus morphogenesis;GO:0072160//nephron tubule epithelial cell differentiation;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis	--
ENSG00000170876	19.057	20.984	19.498	17.161	19.865	21.012	1253	1391	933	846	1083	995.99	TMEM43	transmembrane protein 43 [Source:HGNC Symbol;Acc:HGNC:28472]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043621//protein self-association	GO:0071763//nuclear membrane organization	--
ENSG00000170881	12.916	12.07	12.815	10.173	11.327	11.744	857	805	628	478	635	567	RNF139	ring finger protein 139 [Source:HGNC Symbol;Acc:HGNC:17023]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0044322//endoplasmic reticulum quality control compartment	GO:0002020//protease binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008285//negative regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0017148//negative regulation of translation;GO:0031648//protein destabilization;GO:0036503//ERAD pathway;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0070613//regulation of protein processing;GO:1904380//endoplasmic reticulum mannose trimming;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000170889	514.56	517.643	532.361	632.978	504.596	509.213	7111	7248	5347	6187	5916	5028	RPS9	ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02997;K02997	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0045182//translation regulator activity	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0008284//positive regulation of cell population proliferation;GO:0045903//positive regulation of translational fidelity	--
ENSG00000170890	0	0	0.118	0	0	0	0	0	1	0	0	0	PLA2G1B	phospholipase A2 group IB [Source:HGNC Symbol;Acc:HGNC:9030]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0030141//secretory granule	GO:0004623//phospholipase A2 activity;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0032052//bile acid binding;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0002227//innate immune response in mucosa;GO:0002446//neutrophil mediated immunity;GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0016042//lipid catabolic process;GO:0019370//leukotriene biosynthetic process;GO:0019731//antibacterial humoral response;GO:0030593//neutrophil chemotaxis;GO:0032431//activation of phospholipase A2 activity;GO:0032757//positive regulation of interleukin-8 production;GO:0032869//cellular response to insulin stimulus;GO:0035556//intracellular signal transduction;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0043406//positive regulation of MAP kinase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046324//regulation of glucose import;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0050482//arachidonic acid secretion;GO:0050714//positive regulation of protein secretion;GO:0050778//positive regulation of immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1904635//positive regulation of glomerular visceral epithelial cell apoptotic process	--
ENSG00000170891	6.31	4.801	4.62	7.7	6.174	8.978	127	99	70	117	107	134	CYTL1	cytokine like 1 [Source:HGNC Symbol;Acc:HGNC:24435]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding	GO:0002062//chondrocyte differentiation;GO:0007165//signal transduction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:1990079//cartilage homeostasis	--
ENSG00000170892	29.975	31.513	35.246	42.896	36.766	40.242	1020	1107	896	1032	1029	970	TSEN34	tRNA splicing endonuclease subunit 34 [Source:HGNC Symbol;Acc:HGNC:15506]	-	-	-	-	GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0000213//tRNA-intron endonuclease activity;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0016829//lyase activity	"GO:0000379//tRNA-type intron splice site recognition and cleavage;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0008033//tRNA processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000170893	0.464	0.523	0.293	0.167	0.183	0.085	15	17	7	4	5	2	TRH	thyrotropin releasing hormone [Source:HGNC Symbol;Acc:HGNC:12298]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05253	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0030141//secretory granule	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008437//thyrotropin-releasing hormone activity	GO:0001692//histamine metabolic process;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007628//adult walking behavior;GO:0009755//hormone-mediated signaling pathway;GO:0014050//negative regulation of glutamate secretion;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0032024//positive regulation of insulin secretion;GO:0042755//eating behavior	--
ENSG00000170899	31.674	27.561	28.743	31.073	29.257	28.428	787	703	546	592	633	532	GSTA4	glutathione S-transferase alpha 4 [Source:HGNC Symbol;Acc:HGNC:4629]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000170903	30.031	24.756	21.587	17.406	20.13	20.451	1662	1439	938	762	960	846	MSANTD4	Myb/SANT DNA binding domain containing 4 with coiled-coils [Source:HGNC Symbol;Acc:HGNC:29383]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000170906	23.858	26.039	33.038	32.608	26.569	28.792	225	224	204	265	189	191	NDUFA3	NADH:ubiquinone oxidoreductase subunit A3 [Source:HGNC Symbol;Acc:HGNC:7686]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947;K03947	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000170909	0	0	0	0	0	0	0	0	0	0	0	0	OSCAR	osteoclast associated Ig-like receptor [Source:HGNC Symbol;Acc:HGNC:29960]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K14377	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen	GO:0038064//collagen receptor activity	GO:0030316//osteoclast differentiation;GO:0038065//collagen-activated signaling pathway;GO:0038094//Fc-gamma receptor signaling pathway;GO:0045780//positive regulation of bone resorption;GO:0072674//multinuclear osteoclast differentiation	--
ENSG00000170915	2.669	2.726	2.75	2.747	2.251	2.656	261	268	198	199	186	189	PAQR8	progestin and adipoQ receptor family member 8 [Source:HGNC Symbol;Acc:HGNC:15708]	Human Diseases	Cancer: overview	ko05207//Chemical carcinogenesis - receptor activation	K25040	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038023//signaling receptor activity	GO:0030154//cell differentiation;GO:0043401//steroid hormone mediated signaling pathway;GO:0048477//oogenesis;GO:0048545//response to steroid hormone	--
ENSG00000170917	5.787	3.964	5.331	6.024	6.097	7.507	140.23	97.7	78.33	89.13	102.95	105.85	NUDT6	nudix hydrolase 6 [Source:HGNC Symbol;Acc:HGNC:8053]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0047631//ADP-ribose diphosphatase activity;GO:0051287//NAD binding	GO:0008285//negative regulation of cell population proliferation;GO:0045786//negative regulation of cell cycle	--
ENSG00000170920	0	0	0	0	0	0	0	0	0	0	0	0	OR7G3	olfactory receptor family 7 subfamily G member 3 [Source:HGNC Symbol;Acc:HGNC:8467]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170921	7.356	6.352	5.112	4.54	5.322	4.867	1503	1503	939	831	1106	866	TANC2	"tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Source:HGNC Symbol;Acc:HGNC:30212]"	-	-	-	-	"GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0060998//regulation of dendritic spine development;GO:0061001//regulation of dendritic spine morphogenesis;GO:0099519//dense core granule cytoskeletal transport	--
ENSG00000170923	0	0	0	0	0	0	0	0	0	0	0	0	OR7G2	olfactory receptor family 7 subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:8466]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170925	0	0	0	0	0	0	0	0	0	0	0	0	TEX13B	testis expressed 13B [Source:HGNC Symbol;Acc:HGNC:11736]	-	-	-	-	GO:0005737//cytoplasm	GO:0003729//mRNA binding;GO:0005515//protein binding	-	--
ENSG00000170927	0.021	0.021	0	0.008	0.005	0	5	5	0	2	1	0	PKHD1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0097731//9+0 non-motile cilium"	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0000132//establishment of mitotic spindle orientation;GO:0001822//kidney development;GO:0001952//regulation of cell-matrix adhesion;GO:0003382//epithelial cell morphogenesis;GO:0006874//cellular calcium ion homeostasis;GO:0008284//positive regulation of cell population proliferation;GO:0010824//regulation of centrosome duplication;GO:0022407//regulation of cell-cell adhesion;GO:0030155//regulation of cell adhesion;GO:0032006//regulation of TOR signaling;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0042592//homeostatic process;GO:0043066//negative regulation of apoptotic process;GO:0045216//cell-cell junction organization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051271//negative regulation of cellular component movement;GO:0051660//establishment of centrosome localization;GO:0051898//negative regulation of protein kinase B signaling;GO:0060271//cilium assembly;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0090175//regulation of establishment of planar polarity;GO:0098609//cell-cell adhesion;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:1904054//regulation of cholangiocyte proliferation	--
ENSG00000170929	0	0	0	0	0	0	0	0	0	0	0	0	OR1M1	olfactory receptor family 1 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:8220]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170935	0	0	0	0	0	0	0	0	0	0	0	0	NCBP2L	nuclear cap binding protein subunit 2 like [Source:HGNC Symbol;Acc:HGNC:31795]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12883;K12883;K12883	GO:0005846//nuclear cap binding complex	GO:0000339//RNA cap binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0045292//mRNA cis splicing, via spliceosome"	--
ENSG00000170946	4.842	4.141	4.806	3.685	3.122	5.615	274	256	194	143.52	160	163.25	DNAJC24	DnaJ heat shock protein family (Hsp40) member C24 [Source:HGNC Symbol;Acc:HGNC:26979]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001671//ATPase activator activity;GO:0008198//ferrous iron binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0032781//positive regulation of ATPase activity;GO:0061077//chaperone-mediated protein folding	--
ENSG00000170948	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L1	methyl-CpG binding domain protein 3 like 1 [Source:HGNC Symbol;Acc:HGNC:15774]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	-	--
ENSG00000170949	8.05	6.074	3.99	3.639	5.564	4.994	565	434	252	231	287	243	ZNF160	zinc finger protein 160 [Source:HGNC Symbol;Acc:HGNC:12948]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030097//hemopoiesis"	zf-C2H2
ENSG00000170950	0	0	0	0	0	0	0	0	0	0	0	0	PGK2	phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K00927;K00927;K00927;K00927;K00927	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0035686//sperm fibrous sheath;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004618//phosphoglycerate kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043531//ADP binding	GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0016310//phosphorylation;GO:0030317//flagellated sperm motility	--
ENSG00000170953	0	0	0	0	0	0	0	0	0	0	0	0	OR8B12	olfactory receptor family 8 subfamily B member 12 [Source:HGNC Symbol;Acc:HGNC:15307]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000170954	3.694	4.591	4.561	2.533	3.02	2.873	178	168	139	88	104	93	ZNF415	zinc finger protein 415 [Source:HGNC Symbol;Acc:HGNC:20636]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000170955	5.311	6.876	6.124	5.351	6.971	5.252	113	147	96	84	125	81	CAVIN3	caveolae associated protein 3 [Source:HGNC Symbol;Acc:HGNC:9400]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005901//caveola;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005080//protein kinase C binding;GO:0005515//protein binding	GO:0030866//cortical actin cytoskeleton organization;GO:0032922//circadian regulation of gene expression;GO:0048511//rhythmic process;GO:0051898//negative regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1901003//negative regulation of fermentation	--
ENSG00000170956	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM3	CEA cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:1815]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane	GO:0005515//protein binding	-	--
ENSG00000170959	1.193	0.962	0.882	0.699	1.194	1.029	153	116	71	61	107	95	DCDC1	doublecortin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20625]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0030496//midbody;GO:0072686//mitotic spindle;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0030246//carbohydrate binding	GO:0007049//cell cycle;GO:0035556//intracellular signal transduction;GO:0051301//cell division;GO:1902412//regulation of mitotic cytokinesis	--
ENSG00000170961	0.136	0.17	0.092	0.077	0	0	12	15	6	5	0	0	HAS2	hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819]	-	-	-	-	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0044853//plasma membrane raft	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0050501//hyaluronan synthase activity	GO:0001570//vasculogenesis;GO:0001822//kidney development;GO:0008284//positive regulation of cell population proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030212//hyaluronan metabolic process;GO:0030213//hyaluronan biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0035810//positive regulation of urine volume;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0036302//atrioventricular canal development;GO:0044849//estrous cycle;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0051549//positive regulation of keratinocyte migration;GO:0060349//bone morphogenesis;GO:0070295//renal water absorption;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071498//cellular response to fluid shear stress;GO:0085029//extracellular matrix assembly;GO:0090500//endocardial cushion to mesenchymal transition;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:1900625//positive regulation of monocyte aggregation;GO:1901201//regulation of extracellular matrix assembly	--
ENSG00000170962	10.093	8.42	8.707	8.495	8.883	8.97	816	686	523	510	608	529	PDGFD	platelet derived growth factor D [Source:HGNC Symbol;Acc:HGNC:30620]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05218//Melanoma	K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450;K05450	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane	GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0070851//growth factor receptor binding	GO:0008284//positive regulation of cell population proliferation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0043406//positive regulation of MAP kinase activity;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0070301//cellular response to hydrogen peroxide;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071230//cellular response to amino acid stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071673//positive regulation of smooth muscle cell chemotaxis;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:2000439//positive regulation of monocyte extravasation	--
ENSG00000170965	0	0	0	0	0	0	0	0	0	0	0	0	PLAC1	placenta enriched 1 [Source:HGNC Symbol;Acc:HGNC:9044]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function	GO:0001890//placenta development	--
ENSG00000170967	0	0	0	0	0	0	0	0	0	0	0	0	DDI1	DNA damage inducible 1 homolog 1 [Source:HGNC Symbol;Acc:HGNC:18961]	-	-	-	-	-	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0010498//proteasomal protein catabolic process;GO:0031647//regulation of protein stability;GO:0072711//cellular response to hydroxyurea;GO:0097752//regulation of DNA stability	--
ENSG00000170989	3.793	5.705	2.94	5.761	4.347	3.742	202	291	100	221	184	118	S1PR1	sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04068//FoxO signaling pathway;ko04071//Sphingolipid signaling pathway	K04288;K04288;K04288	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	GO:0001664//G protein-coupled receptor binding;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0038036//sphingosine-1-phosphate receptor activity;GO:0046625//sphingolipid binding	GO:0001525//angiogenesis;GO:0001955//blood vessel maturation;GO:0003245//cardiac muscle tissue growth involved in heart morphogenesis;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0016477//cell migration;GO:0019222//regulation of metabolic process;GO:0019226//transmission of nerve impulse;GO:0030032//lamellipodium assembly;GO:0030155//regulation of cell adhesion;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0030500//regulation of bone mineralization;GO:0030595//leukocyte chemotaxis;GO:0031532//actin cytoskeleton reorganization;GO:0043547//positive regulation of GTPase activity;GO:0045124//regulation of bone resorption;GO:0045446//endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050927//positive regulation of positive chemotaxis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051497//negative regulation of stress fiber assembly;GO:0061384//heart trabecula morphogenesis;GO:0072678//T cell migration	--
ENSG00000171004	0.786	0.815	0.752	0.954	0.769	0.742	69	69	48	59	55	45	HS6ST2	heparan sulfate 6-O-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:19133]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K08102	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0017095//heparan sulfate 6-O-sulfotransferase activity	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:1901137//carbohydrate derivative biosynthetic process"	--
ENSG00000171014	0	0	0	0	0	0	0	0	0	0	0	0	OR4D5	olfactory receptor family 4 subfamily D member 5 [Source:HGNC Symbol;Acc:HGNC:14852]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171016	5.588	4.56	3.997	2.128	3.116	4.2	826	593	455	257	330	340	PYGO1	pygopus family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30256]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007286//spermatid development;GO:0007289//spermatid nucleus differentiation;GO:0016055//Wnt signaling pathway;GO:0034504//protein localization to nucleus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development;GO:0060070//canonical Wnt signaling pathway	--
ENSG00000171017	1.356	1.952	2.659	1.82	1.335	2.416	101	117	87	67	84	86	LRRC8E	leucine rich repeat containing 8 VRAC subunit E [Source:HGNC Symbol;Acc:HGNC:26272]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0034702//ion channel complex;GO:1905103//integral component of lysosomal membrane	GO:0005225//volume-sensitive anion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006884//cell volume homeostasis;GO:0015698//inorganic anion transport;GO:0015810//aspartate transmembrane transport;GO:0071470//cellular response to osmotic stress;GO:0098656//anion transmembrane transport;GO:0140361//cyclic-GMP-AMP transmembrane import across plasma membrane	--
ENSG00000171033	5.942	5.278	5.294	5.216	4.264	4.663	315	270	219	210	200	180	PKIA	cAMP-dependent protein kinase inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:9017]	Human Diseases	Substance dependence	ko05034//Alcoholism	K15985	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0034236//protein kinase A catalytic subunit binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006469//negative regulation of protein kinase activity;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0016310//phosphorylation;GO:0042308//negative regulation of protein import into nucleus;GO:0043086//negative regulation of catalytic activity;GO:0051338//regulation of transferase activity;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000171044	1.547	0.385	0.787	0.735	0.795	1.302	43	23	29	20	23	37	XKR6	XK related 6 [Source:HGNC Symbol;Acc:HGNC:27806]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902742//apoptotic process involved in development	--
ENSG00000171045	4.143	4.056	4.005	3.819	4.805	5.024	156	168	122	117	157	146	TSNARE1	t-SNARE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26437]	-	-	-	-	GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0048278//vesicle docking	--
ENSG00000171049	0	0	0	0	0	0	0	0	0	0	0	0	FPR2	formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827]	Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04080//Neuroactive ligand-receptor interaction;ko04613//Neutrophil extracellular trap formation;ko05150//Staphylococcus aureus infection	K04173;K04173;K04173	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0001540//amyloid-beta binding;GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004982//N-formyl peptide receptor activity;GO:0005124//scavenger receptor binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0038024//cargo receptor activity	GO:0001774//microglial cell activation;GO:0001934//positive regulation of protein phosphorylation;GO:0002430//complement receptor mediated signaling pathway;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0032930//positive regulation of superoxide anion generation;GO:0042742//defense response to bacterium;GO:0045089//positive regulation of innate immune response;GO:0048143//astrocyte activation;GO:0050728//negative regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050918//positive chemotaxis;GO:0061903//positive regulation of 1-phosphatidylinositol-3-kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090026//positive regulation of monocyte chemotaxis;GO:1904646//cellular response to amyloid-beta	--
ENSG00000171051	0.074	0.111	0.066	0.05	0.132	0.36	2	3	2	1	3	7	FPR1	formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Immune system;Signal transduction;Infectious disease: bacterial	ko04080//Neuroactive ligand-receptor interaction;ko04613//Neutrophil extracellular trap formation;ko04015//Rap1 signaling pathway;ko05150//Staphylococcus aureus infection	K04172;K04172;K04172;K04172	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0035577//azurophil granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0001664//G protein-coupled receptor binding;GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004982//N-formyl peptide receptor activity;GO:0005124//scavenger receptor binding;GO:0005515//protein binding;GO:0050786//RAGE receptor binding	GO:0002430//complement receptor mediated signaling pathway;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007263//nitric oxide mediated signal transduction	--
ENSG00000171053	0	0	0	0	0	0	0	0	0	0	0	0	PATE1	prostate and testis expressed 1 [Source:HGNC Symbol;Acc:HGNC:24664]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25370	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0030548//acetylcholine receptor regulator activity	GO:0099601//regulation of neurotransmitter receptor activity	--
ENSG00000171054	0	0	0	0.14	0	0	0	0	0	2	0	0	OR13H1	olfactory receptor family 13 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:14755]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171055	45.267	44.488	49.562	39.47	37.643	42.66	1877	1855	1485	1137	1263	1290	FEZ2	fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660]	-	-	-	-	GO:0005737//cytoplasm;GO:0030424//axon	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000171056	0.015	0.06	0.069	0	0.053	0.041	1	4	3.41	0	3	2	SOX7	SRY-box transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:18196]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001706//endoderm formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060828//regulation of canonical Wnt signaling pathway"	HMG
ENSG00000171060	0	0	0	0	0	0	0	0	0	0	0	0	C8orf74	chromosome 8 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:32296]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000171067	13.737	16.74	14.37	14.02	14.157	12.458	581	695	444	435	507	387	C11orf24	chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000171094	0.326	0.209	0.17	0.09	0.106	0.19	17	12	8	4	6	9	ALK	ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05223//Non-small cell lung cancer	K05119;K05119;K05119	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021766//hippocampus development;GO:0030534//adult behavior;GO:0033674//positive regulation of kinase activity;GO:0036269//swimming behavior;GO:0038061//NIK/NF-kappaB signaling;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045664//regulation of neuron differentiation;GO:0046777//protein autophosphorylation;GO:0048666//neuron development;GO:0050995//negative regulation of lipid catabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0090648//response to environmental enrichment;GO:0097009//energy homeostasis;GO:1900006//positive regulation of dendrite development	--
ENSG00000171097	5.436	6.309	5.411	6.189	5.91	6.587	220.67	220.86	160.8	155.37	175.87	189.41	KYAT1	kynurenine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:1564]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00380//Tryptophan metabolism;ko00450//Selenocompound metabolism	K00816;K00816;K00816;K00816	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0047316//glutamine-phenylpyruvate transaminase activity;GO:0047804//cysteine-S-conjugate beta-lyase activity;GO:0070548//L-glutamine aminotransferase activity	GO:0006575//cellular modified amino acid metabolic process;GO:0009058//biosynthetic process;GO:0070189//kynurenine metabolic process;GO:0097052//L-kynurenine metabolic process;GO:0097053//L-kynurenine catabolic process	--
ENSG00000171100	4.067	3.453	3.593	2.968	3.598	3.248	284	246	180	152	213	165	MTM1	myotubularin 1 [Source:HGNC Symbol;Acc:HGNC:7448]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01108;K01108;K01108	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030175//filopodium;GO:0031674//I band;GO:0042995//cell projection	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019215//intermediate filament binding;GO:0035091//phosphatidylinositol binding;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016311//dephosphorylation;GO:0032007//negative regulation of TOR signaling;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0044088//regulation of vacuole organization;GO:0045109//intermediate filament organization;GO:0046716//muscle cell cellular homeostasis;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048311//mitochondrion distribution;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0051898//negative regulation of protein kinase B signaling;GO:0070584//mitochondrion morphogenesis;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000171102	0	0	0	0	0.082	0	0	0	0	0	1	0	OBP2B	odorant binding protein 2B [Source:HGNC Symbol;Acc:HGNC:23381]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005549//odorant binding;GO:0036094//small molecule binding	GO:0007608//sensory perception of smell;GO:0007635//chemosensory behavior;GO:0050896//response to stimulus	--
ENSG00000171103	8.108	7.287	8.068	8.112	6.528	10.722	291.88	276	221.74	226	203.93	287.81	TRMT61B	tRNA methyltransferase 61B [Source:HGNC Symbol;Acc:HGNC:26070]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031515//tRNA (m1A) methyltransferase complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016429//tRNA (adenine-N1-)-methyltransferase activity;GO:0016433//rRNA (adenine) methyltransferase activity;GO:0016740//transferase activity;GO:0061953//mRNA (adenine-N1-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0051260//protein homooligomerization;GO:0070901//mitochondrial tRNA methylation;GO:0080009//mRNA methylation	--
ENSG00000171105	12.863	10.832	12.778	9.149	11.579	13.726	2321	1970	1704	1204	1821	1836	INSR	insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Signal transduction;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Aging;Cellular community - eukaryotes;Aging;Endocrine system;Endocrine system;Endocrine and metabolic disease;Excretory system	ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko04211//Longevity regulating pathway;ko04520//Adherens junction;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04930//Type II diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption	K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527;K04527	GO:0005635//nuclear envelope;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005899//insulin receptor complex;GO:0005901//caveola;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0031981//nuclear lumen;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001540//amyloid-beta binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005009//insulin-activated receptor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding;GO:0038024//cargo receptor activity;GO:0042802//identical protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043559//insulin binding;GO:0043560//insulin receptor substrate binding;GO:0044877//protein-containing complex binding;GO:0051425//PTB domain binding	"GO:0001934//positive regulation of protein phosphorylation;GO:0002092//positive regulation of receptor internalization;GO:0003007//heart morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006898//receptor-mediated endocytosis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007612//learning;GO:0007613//memory;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0008544//epidermis development;GO:0008584//male gonad development;GO:0009887//animal organ morphogenesis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030238//male sex determination;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0031017//exocrine pancreas development;GO:0032147//activation of protein kinase activity;GO:0032148//activation of protein kinase B activity;GO:0032869//cellular response to insulin stimulus;GO:0033674//positive regulation of kinase activity;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042593//glucose homeostasis;GO:0043243//positive regulation of protein-containing complex disassembly;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045821//positive regulation of glycolytic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0046326//positive regulation of glucose import;GO:0046718//viral entry into host cell;GO:0046777//protein autophosphorylation;GO:0048639//positive regulation of developmental growth;GO:0051446//positive regulation of meiotic cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0060267//positive regulation of respiratory burst;GO:0071363//cellular response to growth factor stimulus;GO:0097062//dendritic spine maintenance;GO:0097242//amyloid-beta clearance;GO:0150104//transport across blood-brain barrier;GO:1990535//neuron projection maintenance;GO:2000194//regulation of female gonad development"	--
ENSG00000171109	11.038	8.641	8.546	7.073	7.055	7.86	796	644.43	461	384.04	457	407	MFN1	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	Human Diseases;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Immune system;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04621//NOD-like receptor signaling pathway;ko04137//Mitophagy - animal	K21356;K21356;K21356;K21356	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0098799//outer mitochondrial membrane protein complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0007005//mitochondrion organization;GO:0008053//mitochondrial fusion;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0046039//GTP metabolic process;GO:0051646//mitochondrion localization;GO:1990613//mitochondrial membrane fusion	--
ENSG00000171115	0	0	0	0	0.014	0	0	0	0	0	1	0	GIMAP8	"GTPase, IMAP family member 8 [Source:HGNC Symbol;Acc:HGNC:21792]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005525//GTP binding	GO:0070232//regulation of T cell apoptotic process	--
ENSG00000171116	0.737	0.562	0.532	0.265	0.407	0.304	30	23	16	8	14	9	HSFX1	"heat shock transcription factor family, X-linked 1 [Source:HGNC Symbol;Acc:HGNC:29603]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000171119	0.915	1.004	0.726	1.746	0.859	1.127	29	32	17	41	23	26	NRTN	neurturin [Source:HGNC Symbol;Acc:HGNC:8007]	-	-	-	-	GO:0005576//extracellular region;GO:0030424//axon	GO:0005102//signaling receptor binding;GO:0008083//growth factor activity;GO:0030116//glial cell-derived neurotrophic factor receptor binding;GO:0030971//receptor tyrosine kinase binding	GO:0000165//MAPK cascade;GO:0001755//neural crest cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0021675//nerve development;GO:0031175//neuron projection development	--
ENSG00000171121	0.591	0.213	0.358	0.455	0.311	0.343	35	13.05	19.54	14.77	10.49	17.47	KCNMB3	potassium calcium-activated channel subfamily M regulatory beta subunit 3 [Source:HGNC Symbol;Acc:HGNC:6287]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K04939;K04939;K04939	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015269//calcium-activated potassium channel activity;GO:0015459//potassium channel regulator activity	GO:0001508//action potential;GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0019228//neuronal action potential;GO:0071805//potassium ion transmembrane transport	--
ENSG00000171124	0	0.047	0	0	0	0	0	2	0	0	0	0	FUT3	fucosyltransferase 3 (Lewis blood group) [Source:HGNC Symbol;Acc:HGNC:4014]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K00716;K00716	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0009988//cell-cell recognition;GO:0022409//positive regulation of cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0036065//fucosylation;GO:0042127//regulation of cell population proliferation;GO:0043413//macromolecule glycosylation	--
ENSG00000171126	0	0	0.018	0.018	0	0.036	0	0	1	1	0	2	KCNG3	potassium voltage-gated channel modifier subfamily G member 3 [Source:HGNC Symbol;Acc:HGNC:18306]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000171130	62.027	65.767	65.432	78.887	72.509	67.056	2196	2365	1711	2018	2146	1742	ATP6V0E2	ATPase H+ transporting V0 subunit e2 [Source:HGNC Symbol;Acc:HGNC:21723]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02153;K02153;K02153;K02153;K02153;K02153;K02153;K02153;K02153	"GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain"	"GO:0016787//hydrolase activity;GO:0042625//ATPase-coupled ion transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0016241//regulation of macroautophagy;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000171132	0.503	0.517	0.182	0.883	0.476	0.952	60	62	16	78	48	63	PRKCE	protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401]	Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: bacterial;Cellular community - eukaryotes;Signal transduction;Cancer: overview;Immune system;Signal transduction;Circulatory system;Signal transduction;Endocrine and metabolic disease;Endocrine and metabolic disease;Sensory system;Endocrine system;Endocrine and metabolic disease	ko05131//Shigellosis;ko04530//Tight junction;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04371//Apelin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04071//Sphingolipid signaling pathway;ko04931//Insulin resistance;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04930//Type II diabetes mellitus	K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050;K18050	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0003785//actin monomer binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004699//calcium-independent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008047//enzyme activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0030546//signaling receptor activator activity;GO:0035276//ethanol binding;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding;GO:0106310//protein serine kinase activity	"GO:0002281//macrophage activation involved in immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0010634//positive regulation of epithelial cell migration;GO:0010763//positive regulation of fibroblast migration;GO:0010811//positive regulation of cell-substrate adhesion;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0019216//regulation of lipid metabolic process;GO:0030168//platelet activation;GO:0030838//positive regulation of actin filament polymerization;GO:0031397//negative regulation of protein ubiquitination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032467//positive regulation of cytokinesis;GO:0035556//intracellular signal transduction;GO:0035641//locomotory exploration behavior;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043278//response to morphine;GO:0043410//positive regulation of MAPK cascade;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050790//regulation of catalytic activity;GO:0050996//positive regulation of lipid catabolic process;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0051301//cell division;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070257//positive regulation of mucus secretion;GO:0071361//cellular response to ethanol;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071456//cellular response to hypoxia;GO:0080090//regulation of primary metabolic process;GO:0090303//positive regulation of wound healing;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:2001031//positive regulation of cellular glucuronidation"	--
ENSG00000171133	0	0	0	0	0	0	0	0	0	0	0	0	OR2K2	olfactory receptor family 2 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:8264]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171135	20.192	19.716	23.503	19.651	20.481	23.208	678	663	583	490	572	563	JAGN1	jagunal homolog 1 [Source:HGNC Symbol;Acc:HGNC:26926]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002376//immune system process;GO:0002446//neutrophil mediated immunity;GO:0006887//exocytosis;GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030223//neutrophil differentiation;GO:0038158//granulocyte colony-stimulating factor signaling pathway;GO:0050832//defense response to fungus;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1904577//cellular response to tunicamycin;GO:1990266//neutrophil migration	--
ENSG00000171136	0	0	0	0	0	0	0	0	0	0	0	0	RLN3	relaxin 3 [Source:HGNC Symbol;Acc:HGNC:17135]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K22000;K22000	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000171148	43.811	47.724	43.806	51.471	48.841	42.828	1720	1914.08	1293	1472	1611	1237	TADA3	transcriptional adaptor 3 [Source:HGNC Symbol;Acc:HGNC:19422]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K11315	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0033276//transcription factor TFTC complex;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0019904//protein domain specific binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000278//mitotic cell cycle;GO:0001932//regulation of protein phosphorylation;GO:0006282//regulation of DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0016573//histone acetylation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031063//regulation of histone deacetylation;GO:0031647//regulation of protein stability;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000171150	9.559	8.534	9.285	8.849	9.322	10.093	945	848	678	648	764	726	SOCS5	suppressor of cytokine signaling 5 [Source:HGNC Symbol;Acc:HGNC:16852]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K04698;K04698	GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032715//negative regulation of interleukin-6 production;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0097699//vascular endothelial cell response to fluid shear stress	--
ENSG00000171155	19.744	16.711	20.748	15.357	14.999	17.78	670	570	520	386	430	439	C1GALT1C1	C1GALT1 specific chaperone 1 [Source:HGNC Symbol;Acc:HGNC:24338]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K09653;K09653;K09653	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016263//glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	"GO:0006493//protein O-linked glycosylation;GO:0016267//O-glycan processing, core 1;GO:0030168//platelet activation;GO:0036344//platelet morphogenesis"	--
ENSG00000171159	82.795	90.343	81.782	119.448	98.647	85.367	1209	1326	882	1292	1217	907	BBLN	bublin coiled coil protein [Source:HGNC Symbol;Acc:HGNC:17823]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000171160	11.447	10.236	11.638	10.788	10.605	12.75	414	441	358	339	367	374	MORN4	MORN repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:24001]	-	-	-	-	GO:0005737//cytoplasm;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0032433//filopodium tip;GO:0042995//cell projection	GO:0005515//protein binding	GO:0048678//response to axon injury	--
ENSG00000171161	15.753	14.586	16.887	19.232	20.746	18.932	957	926	748	851	997	870	ZNF672	zinc finger protein 672 [Source:HGNC Symbol;Acc:HGNC:26179]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000171163	3.296	4.38	4.329	4.01	5.302	4.759	126	160	127	107	163	112	ZNF692	zinc finger protein 692 [Source:HGNC Symbol;Acc:HGNC:26049]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006111//regulation of gluconeogenesis;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000171169	1.774	2.033	3.016	2.088	2.368	2.223	125	144	157	109	141	114	NAIF1	nuclear apoptosis inducing factor 1 [Source:HGNC Symbol;Acc:HGNC:25446]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0030308//negative regulation of cell growth;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process	--
ENSG00000171174	2.395	2.914	2.825	3.307	1.813	1.323	63	76	56	64	40	26	RBKS	ribokinase [Source:HGNC Symbol;Acc:HGNC:30325]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00030//Pentose phosphate pathway	K00852;K00852	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0004747//ribokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006014//D-ribose metabolic process;GO:0006098//pentose-phosphate shunt;GO:0016310//phosphorylation;GO:0019303//D-ribose catabolic process;GO:0046835//carbohydrate phosphorylation	--
ENSG00000171180	0	0	0	0	0	0	0	0	0	0	0	0	OR2M4	olfactory receptor family 2 subfamily M member 4 [Source:HGNC Symbol;Acc:HGNC:8270]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171189	1.356	1.332	0.914	0.64	0.879	0.607	97	96	46	33	52	31	GRIK1	glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04724//Glutamatergic synapse	K05201;K05201	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0110165//cellular anatomical entity	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity;GO:0038023//signaling receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0050804//modulation of chemical synaptic transmission;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential"	--
ENSG00000171195	0	0	0	0	0	0	0	0	0	0	0	0	MUC7	"mucin 7, secreted [Source:HGNC Symbol;Acc:HGNC:7518]"	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13909	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0031640//killing of cells of other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000171199	0	0	0	0	0	0	0	0	0	0	0	0	OPRPN	opiorphin prepropeptide [Source:HGNC Symbol;Acc:HGNC:17279]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004866//endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0001895//retina homeostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0051930//regulation of sensory perception of pain	--
ENSG00000171201	0	0	0	0	0	0	0	0	0	0	0	0	SMR3B	submaxillary gland androgen regulated protein 3B [Source:HGNC Symbol;Acc:HGNC:17326]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding	GO:0008150//biological_process;GO:0010951//negative regulation of endopeptidase activity;GO:0051930//regulation of sensory perception of pain	--
ENSG00000171202	7.485	8.503	9.553	10.205	7.819	8.468	117	134	111	119	104	97	TMEM126A	transmembrane protein 126A [Source:HGNC Symbol;Acc:HGNC:25382]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0021554//optic nerve development;GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000171204	34.527	29.872	30.955	31.921	29.882	27.582	615	581	418	453	455	401	TMEM126B	transmembrane protein 126B [Source:HGNC Symbol;Acc:HGNC:30883]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000171206	29.075	28.68	26.564	24.985	27.219	28.789	1612	1620	1105	1043	1318	1174	TRIM8	tripartite motif containing 8 [Source:HGNC Symbol;Acc:HGNC:15579]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0019827//stem cell population maintenance;GO:0032897//negative regulation of viral transcription;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1900182//positive regulation of protein localization to nucleus"	--
ENSG00000171208	24.095	22.543	23.865	28.168	24.88	27.857	1248	1196	942	1006	1119	979	NETO2	neuropilin and tolloid like 2 [Source:HGNC Symbol;Acc:HGNC:14644]	-	-	-	-	GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding	GO:2000312//regulation of kainate selective glutamate receptor activity	--
ENSG00000171209	0	0	0	0	0	0	0	0	0	0	0	0	CSN3	casein kappa [Source:HGNC Symbol;Acc:HGNC:2446]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007595//lactation;GO:0050821//protein stabilization	--
ENSG00000171217	0	0	0	0	0	0.055	0	0	0	0	0	1	CLDN20	claudin 20 [Source:HGNC Symbol;Acc:HGNC:2042]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0070160//tight junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000171219	0.806	0.864	0.879	0.771	1.037	0.742	103	111	83	73	112	69	CDC42BPG	CDC42 binding protein kinase gamma [Source:HGNC Symbol;Acc:HGNC:29829]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0034451//centriolar satellite	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization	--
ENSG00000171222	42.16	44.597	49.635	58.465	53.109	62.047	759	802.67	651.19	775.19	802.02	792.26	SCAND1	SCAN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:10566]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000171223	34.538	34.624	30.712	18.139	23.512	20.856	1311	1321	861	510	754	576	JUNB	"JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205]"	Organismal Systems;Organismal Systems;Environmental Information Processing	Development and regeneration;Endocrine system;Signal transduction	"ko04380//Osteoclast differentiation;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway"	K09028;K09028;K09028	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0035976//transcription factor AP-1 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001570//vasculogenesis;GO:0001649//osteoblast differentiation;GO:0001701//in utero embryonic development;GO:0001829//trophectodermal cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030316//osteoclast differentiation;GO:0033687//osteoblast proliferation;GO:0042127//regulation of cell population proliferation;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046697//decidualization;GO:0051726//regulation of cell cycle;GO:0060136//embryonic process involved in female pregnancy;GO:0060716//labyrinthine layer blood vessel development;GO:0071277//cellular response to calcium ion;GO:0140467//integrated stress response signaling;GO:2000319//regulation of T-helper 17 cell differentiation"	TF_bZIP
ENSG00000171224	4.583	4.917	6.144	5.823	5.478	6.052	102	110	101	96	103	98	FAM241B	family with sequence similarity 241 member B [Source:HGNC Symbol;Acc:HGNC:23519]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000171227	22.222	18.907	25.427	39.156	34.674	45.511	728	665	641	997	1020	1154	TMEM37	transmembrane protein 37 [Source:HGNC Symbol;Acc:HGNC:18216]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005262//calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport	--
ENSG00000171234	0.208	0.364	0.104	0	0	0.369	6	8	3	0	0	9	UGT2B7	UDP glucuronosyltransferase family 2 member B7 [Source:HGNC Symbol;Acc:HGNC:12554]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000171236	0.019	0.037	0	0.025	0	0	1	2	0	1	0	0	LRG1	leucine rich alpha-2-glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:29480]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0003674//molecular_function;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0034713//type I transforming growth factor beta receptor binding	"GO:0001938//positive regulation of endothelial cell proliferation;GO:0008150//biological_process;GO:0009617//response to bacterium;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010838//positive regulation of keratinocyte proliferation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0035313//wound healing, spreading of epidermal cells;GO:0045766//positive regulation of angiogenesis;GO:0050873//brown fat cell differentiation;GO:0051546//keratinocyte migration;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0061756//leukocyte adhesion to vascular endothelial cell"	--
ENSG00000171241	0.205	0.259	0.164	0.126	0.165	0.154	22	28	13	10	15	12	SHCBP1	SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding;GO:0042169//SH2 domain binding	GO:0008543//fibroblast growth factor receptor signaling pathway;GO:2000177//regulation of neural precursor cell proliferation	--
ENSG00000171243	133.572	136.38	197.401	210.963	181.344	183.667	4933	5057	5378	5752	5646	4929	SOSTDC1	sclerostin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21748]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0036122//BMP binding;GO:0098821//BMP receptor activity	GO:0007389//pattern specification process;GO:0010454//negative regulation of cell fate commitment;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030509//BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045662//negative regulation of myoblast differentiation;GO:0060648//mammary gland bud morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000016//negative regulation of determination of dorsal identity	--
ENSG00000171246	1.587	1.754	1.985	0.826	0.829	0.451	179	187	155	66	79	36	NPTX1	neuronal pentraxin 1 [Source:HGNC Symbol;Acc:HGNC:7952]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043083//synaptic cleft;GO:0098978//glutamatergic synapse	GO:0046872//metal ion binding	GO:0006839//mitochondrial transport;GO:0007268//chemical synaptic transmission;GO:0007417//central nervous system development;GO:0035865//cellular response to potassium ion;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0060385//axonogenesis involved in innervation;GO:0071333//cellular response to glucose stimulus;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0099151//regulation of postsynaptic density assembly;GO:0099645//neurotransmitter receptor localization to postsynaptic specialization membrane	--
ENSG00000171262	8.341	5.546	10.566	6.319	5.397	5.421	643	505	402	426	415	359	FAM98B	family with sequence similarity 98 member B [Source:HGNC Symbol;Acc:HGNC:26773]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0072669//tRNA-splicing ligase complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008276//protein methyltransferase activity;GO:0042802//identical protein binding	GO:0006479//protein methylation;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression	--
ENSG00000171291	1.184	0.857	1.815	0.625	0.884	1.195	62	46	54	24	40	38	ZNF439	zinc finger protein 439 [Source:HGNC Symbol;Acc:HGNC:20873]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171295	2.084	1.472	1.326	0.973	1.394	1.415	145	112	78	63	103	90	ZNF440	zinc finger protein 440 [Source:HGNC Symbol;Acc:HGNC:20874]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171298	27.651	32.682	32.555	30.639	34.671	30.433	1766	1980	1454	1450	1804	1317	GAA	alpha glucosidase [Source:HGNC Symbol;Acc:HGNC:4065]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K12316;K12316;K12316;K12316	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0032450//maltose alpha-glucosidase activity;GO:0090599//alpha-glucosidase activity"	GO:0000023//maltose metabolic process;GO:0002026//regulation of the force of heart contraction;GO:0002086//diaphragm contraction;GO:0003007//heart morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0005985//sucrose metabolic process;GO:0006006//glucose metabolic process;GO:0006941//striated muscle contraction;GO:0007040//lysosome organization;GO:0007626//locomotory behavior;GO:0008152//metabolic process;GO:0009888//tissue development;GO:0043181//vacuolar sequestering;GO:0046716//muscle cell cellular homeostasis;GO:0050884//neuromuscular process controlling posture;GO:0050885//neuromuscular process controlling balance;GO:0060048//cardiac muscle contraction	--
ENSG00000171302	22.226	26.612	24.95	24.664	23.247	23.475	1430	1529	1094	1093	1212	1065	CANT1	calcium activated nucleotidase 1 [Source:HGNC Symbol;Acc:HGNC:19721]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K12304;K12304;K12304	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004382//guanosine-diphosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0043262//adenosine-diphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:0046872//metal ion binding	GO:0030166//proteoglycan biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000171303	0.109	0.147	0.158	0.147	0.194	0.31	14	19	15	14	21	29	KCNK3	potassium two pore domain channel subfamily K member 3 [Source:HGNC Symbol;Acc:HGNC:6278]	Human Diseases;Organismal Systems;Organismal Systems	Endocrine and metabolic disease;Endocrine system;Endocrine system	ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion	K04914;K04914;K04914	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005252//open rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0008022//protein C-terminus binding;GO:0022841//potassium ion leak channel activity;GO:0044548//S100 protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0009410//response to xenobiotic stimulus;GO:0030322//stabilization of membrane potential;GO:0034220//ion transmembrane transport;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0071294//cellular response to zinc ion;GO:0071456//cellular response to hypoxia;GO:0071805//potassium ion transmembrane transport;GO:0090102//cochlea development	--
ENSG00000171307	24.351	26.92	26.537	25.91	23.96	28.094	807	899	638	653	679	690	ZDHHC16	zinc finger DHHC-type palmitoyltransferase 16 [Source:HGNC Symbol;Acc:HGNC:20714]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0001654//eye development;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007507//heart development;GO:0018345//protein palmitoylation;GO:0021537//telencephalon development	--
ENSG00000171310	20.926	16.6	18.34	18.288	17.029	19.414	2018	1922	1523	1339	1705	1675	CHST11	carbohydrate sulfotransferase 11 [Source:HGNC Symbol;Acc:HGNC:17422]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K01017	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047756//chondroitin 4-sulfotransferase activity;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	GO:0001701//in utero embryonic development;GO:0002063//chondrocyte development;GO:0005975//carbohydrate metabolic process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009791//post-embryonic development;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030326//embryonic limb morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0033037//polysaccharide localization;GO:0036342//post-anal tail morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0048589//developmental growth;GO:0048703//embryonic viscerocranium morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0051216//cartilage development	--
ENSG00000171311	8.533	10.172	10.551	9.563	9.802	9.136	196	220	157	158	157	135	EXOSC1	exosome component 1 [Source:HGNC Symbol;Acc:HGNC:17286]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K07573	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101019//nucleolar exosome (RNase complex)	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process	--
ENSG00000171314	240.736	253.745	256.762	291.913	275.475	250.812	8998	9533	7088	8082	8699	6821	PGAM1	phosphoglycerate mutase 1 [Source:HGNC Symbol;Acc:HGNC:8888]	Metabolism;Metabolism;Organismal Systems;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Endocrine system;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00260//Glycine, serine and threonine metabolism"	K01834;K01834;K01834;K01834;K01834;K01834;K01834	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	"GO:0003824//catalytic activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0019901//protein kinase binding"	GO:0006096//glycolytic process;GO:0006110//regulation of glycolytic process;GO:0043456//regulation of pentose-phosphate shunt;GO:0045730//respiratory burst	--
ENSG00000171316	3.145	1.779	1.444	2.692	1.064	1.308	484	415	248	160	209	223	CHD7	chromodomain helicase DNA binding protein 7 [Source:HGNC Symbol;Acc:HGNC:20626]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity;GO:1990841//promoter-specific chromatin binding	"GO:0001501//skeletal system development;GO:0001568//blood vessel development;GO:0001701//in utero embryonic development;GO:0001974//blood vessel remodeling;GO:0003007//heart morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003226//right ventricular compact myocardium morphogenesis;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006364//rRNA processing;GO:0007417//central nervous system development;GO:0007512//adult heart development;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0007628//adult walking behavior;GO:0008015//blood circulation;GO:0009617//response to bacterium;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0021545//cranial nerve development;GO:0021553//olfactory nerve development;GO:0021772//olfactory bulb development;GO:0030217//T cell differentiation;GO:0030540//female genitalia development;GO:0032508//DNA duplex unwinding;GO:0035116//embryonic hindlimb morphogenesis;GO:0035904//aorta development;GO:0035909//aorta morphogenesis;GO:0036302//atrioventricular canal development;GO:0040018//positive regulation of multicellular organism growth;GO:0042048//olfactory behavior;GO:0042471//ear morphogenesis;GO:0042472//inner ear morphogenesis;GO:0043010//camera-type eye development;GO:0043584//nose development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048752//semicircular canal morphogenesis;GO:0048771//tissue remodeling;GO:0048806//genitalia development;GO:0048844//artery morphogenesis;GO:0050767//regulation of neurogenesis;GO:0050890//cognition;GO:0060021//roof of mouth development;GO:0060041//retina development in camera-type eye;GO:0060123//regulation of growth hormone secretion;GO:0060173//limb development;GO:0060324//face development;GO:0060384//innervation;GO:0060411//cardiac septum morphogenesis;GO:0060429//epithelium development;GO:0062009//secondary palate development"	--
ENSG00000171320	0.327	0.19	0.094	0.037	0.212	0.326	10	12.2	1	2.12	12.16	6.03	ESCO2	establishment of sister chromatid cohesion N-acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:27230]	-	-	-	-	GO:0000785//chromatin;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005721//pericentric heterochromatin;GO:0005794//Golgi apparatus;GO:0010369//chromocenter;GO:0030054//cell junction;GO:0035861//site of double-strand break	"GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0046872//metal ion binding"	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006275//regulation of DNA replication;GO:0006302//double-strand break repair;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0034421//post-translational protein acetylation;GO:0071168//protein localization to chromatin	--
ENSG00000171345	80.624	79.022	61.007	147.544	150.879	117.934	2321	2287	1293	3151	3657	2474	KRT19	keratin 19 [Source:HGNC Symbol;Acc:HGNC:6436]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030018//Z disc;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:1990357//terminal web	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0007219//Notch signaling pathway;GO:0030855//epithelial cell differentiation;GO:0043627//response to estrogen;GO:0045109//intermediate filament organization;GO:0045214//sarcomere organization;GO:0060706//cell differentiation involved in embryonic placenta development	--
ENSG00000171346	0.154	0	0.072	0.038	0.278	0.143	3	0	1	1	9	2	KRT15	keratin 15 [Source:HGNC Symbol;Acc:HGNC:6421]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0097110//scaffold protein binding	GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000171357	3.546	4.099	3.106	4.451	3.561	4.049	136	158	87.97	126.44	115.39	113	LURAP1	leucine rich adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:32327]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0001819//positive regulation of cytokine production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000171360	0	0	0	0	0	0	0	0	0	0	0	0	KRT38	keratin 38 [Source:HGNC Symbol;Acc:HGNC:6456]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000171365	5.744	5.766	5.306	4.584	5.203	6.712	1151	1172	789	682	873	872	CLCN5	chloride voltage-gated channel 5 [Source:HGNC Symbol;Acc:HGNC:2023]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K05012	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell	GO:0000166//nucleotide binding;GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0042802//identical protein binding	GO:0003014//renal system process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006897//endocytosis;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000171368	3.564	3.634	3.93	4.376	4.992	4.433	442	453	360	402	523	400	TPPP	tubulin polymerization promoting protein [Source:HGNC Symbol;Acc:HGNC:24164]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle;GO:0097427//microtubule bundle;GO:0150051//postsynaptic Golgi apparatus	GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0001578//microtubule bundle formation;GO:0007049//cell cycle;GO:0014003//oligodendrocyte development;GO:0030953//astral microtubule organization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031643//positive regulation of myelination;GO:0032273//positive regulation of protein polymerization;GO:0032288//myelin assembly;GO:0046785//microtubule polymerization;GO:0048709//oligodendrocyte differentiation;GO:0051301//cell division;GO:0051418//microtubule nucleation by microtubule organizing center;GO:0070507//regulation of microtubule cytoskeleton organization;GO:1904428//negative regulation of tubulin deacetylation	--
ENSG00000171385	2.541	1.784	2.202	1.597	1.697	2.035	401.55	283.46	257.01	187	226.56	234	KCND3	potassium voltage-gated channel subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:6239]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K04893	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:0099060//integral component of postsynaptic specialization membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0086009//membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0099625//ventricular cardiac muscle cell membrane repolarization	--
ENSG00000171388	0.793	0.803	0.405	0.343	0.531	0.123	53	54	20	17	30	6	APLN	apelin [Source:HGNC Symbol;Acc:HGNC:16665]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04371//Apelin signaling pathway	K05225;K05225	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0031704//apelin receptor binding	GO:0001525//angiogenesis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007369//gastrulation;GO:0007595//lactation;GO:0010629//negative regulation of gene expression;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0042756//drinking behavior;GO:0045776//negative regulation of blood pressure;GO:0045823//positive regulation of heart contraction;GO:0060183//apelin receptor signaling pathway;GO:0060976//coronary vasculature development;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904022//positive regulation of G protein-coupled receptor internalization;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1905564//positive regulation of vascular endothelial cell proliferation	--
ENSG00000171396	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-4	keratin associated protein 4-4 [Source:HGNC Symbol;Acc:HGNC:16928]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000171401	0.084	0	0.09	0	0	0	3	0	2	0	0	0	KRT13	keratin 13 [Source:HGNC Symbol;Acc:HGNC:6415]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000171402	0	0	0	0	0	0	0	0	0	0	0	0	XAGE3	X antigen family member 3 [Source:HGNC Symbol;Acc:HGNC:14618]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000171403	0	0	0	0	0	0	0	0	0	0	0	0	KRT9	keratin 9 [Source:HGNC Symbol;Acc:HGNC:6447]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton	GO:0007283//spermatogenesis;GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0043588//skin development;GO:0045109//intermediate filament organization	--
ENSG00000171405	0	0	0	0	0	0	0	0	0	0	0	0	XAGE5	X antigen family member 5 [Source:HGNC Symbol;Acc:HGNC:30930]	-	-	-	-	-	-	-	--
ENSG00000171408	0.188	0.128	0.087	0.149	0.218	0.19	21	14	7	12	20	15	PDE7B	phosphodiesterase 7B [Source:HGNC Symbol;Acc:HGNC:8792]	Metabolism;Metabolism;Human Diseases	Global and overview maps;Nucleotide metabolism;Substance dependence	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko05032//Morphine addiction	K18436;K18436;K18436	GO:0005829//cytosol;GO:0045202//synapse	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0019933//cAMP-mediated signaling	--
ENSG00000171421	13.967	13.951	11.401	13.44	11.837	19.044	180	180	110	128	128	177	MRPL36	mitochondrial ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:14490]	Genetic Information Processing	Translation	ko03010//Ribosome	K02919	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0016604//nuclear body	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation;GO:0042254//ribosome biogenesis	--
ENSG00000171425	11.413	11.845	11.215	15.497	11.489	12.706	284.06	293	203	285	241	227	ZNF581	zinc finger protein 581 [Source:HGNC Symbol;Acc:HGNC:25017]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000171428	1.353	1.604	1.052	1.26	1.066	0.9	47	61	29	32	27	22	NAT1	N-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:7645]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Cancer: overview;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko05204//Chemical carcinogenesis - DNA adducts;ko00232//Caffeine metabolism	K00622;K00622;K00622;K00622	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004060//arylamine N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006805//xenobiotic metabolic process	--
ENSG00000171431	0	0	0	0	0.032	0	0	0	0	0	1	0	KRT20	keratin 20 [Source:HGNC Symbol;Acc:HGNC:20412]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0009267//cellular response to starvation;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization;GO:0050708//regulation of protein secretion	--
ENSG00000171433	0	0	0	0.548	0	0	0	0	0	5	0	0	GLOD5	glyoxalase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:33358]	-	-	-	-	-	-	-	--
ENSG00000171435	0.006	0.011	0.012	0.015	0.013	0.019	2	4	3	4	4	5	KSR2	kinase suppressor of ras 2 [Source:HGNC Symbol;Acc:HGNC:18610]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K18529	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000171443	4.063	5.338	5.454	5.815	6.23	6.693	102	116	99	107	130	105	ZNF524	zinc finger protein 524 [Source:HGNC Symbol;Acc:HGNC:28322]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000171444	10.633	11.342	9.02	5.517	6.579	6.96	1812	1928	1141	700	892	792	MCC	MCC regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:6935]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007165//signal transduction;GO:0010633//negative regulation of epithelial cell migration;GO:0016055//Wnt signaling pathway;GO:0045184//establishment of protein localization;GO:0050680//negative regulation of epithelial cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000171446	0	0	0	0	0	0	0	0	0	0	0	0	KRT27	keratin 27 [Source:HGNC Symbol;Acc:HGNC:30841]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008150//biological_process;GO:0031069//hair follicle morphogenesis;GO:0045109//intermediate filament organization	--
ENSG00000171448	3.289	2.712	3.513	2.824	2.551	2.779	278	237	220	171	185	163	ZBTB26	zinc finger and BTB domain containing 26 [Source:HGNC Symbol;Acc:HGNC:23383]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	ZBTB
ENSG00000171450	0.174	0.039	0.157	0.105	0.069	0.133	9	2	6	4	3	5	CDK5R2	cyclin dependent kinase 5 regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:1776]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016533//protein kinase 5 complex;GO:0030426//growth cone;GO:0043005//neuron projection	GO:0003779//actin binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001764//neuron migration;GO:0007411//axon guidance;GO:0007420//brain development;GO:0021549//cerebellum development;GO:0021722//superior olivary nucleus maturation;GO:0021766//hippocampus development;GO:0021819//layer formation in cerebral cortex;GO:0032147//activation of protein kinase activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0045956//positive regulation of calcium ion-dependent exocytosis	--
ENSG00000171451	3.408	2.671	2.846	2.536	2.568	2.86	655	516	404	361	417	400	DSEL	dermatan sulfate epimerase like [Source:HGNC Symbol;Acc:HGNC:18144]	-	-	-	-	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0016853//isomerase activity;GO:0047757//chondroitin-glucuronate 5-epimerase activity	GO:0030204//chondroitin sulfate metabolic process;GO:0030205//dermatan sulfate metabolic process;GO:0030208//dermatan sulfate biosynthetic process	--
ENSG00000171453	7.822	7.689	8.137	7.973	8.63	9.362	209	208	158	156	172	179	POLR1C	RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03027;K03027	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol	GO:0001054//RNA polymerase I activity;GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006360//transcription by RNA polymerase I;GO:0006383//transcription by RNA polymerase III"	--
ENSG00000171456	12.727	13.497	14.86	13.169	12.947	12.835	1691	1721	1351	1270	1439	1292	ASXL1	ASXL transcriptional regulator 1 [Source:HGNC Symbol;Acc:HGNC:18318]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035517//PR-DUB complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042974//retinoic acid receptor binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0046872//metal ion binding	"GO:0000902//cell morphogenesis;GO:0003007//heart morphogenesis;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0009887//animal organ morphogenesis;GO:0030097//hemopoiesis;GO:0032526//response to retinoic acid;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0035564//regulation of kidney size;GO:0045599//negative regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0048534//hematopoietic or lymphoid organ development;GO:0048538//thymus development;GO:0048539//bone marrow development;GO:0048872//homeostasis of number of cells;GO:0060348//bone development;GO:0060430//lung saccule development;GO:0072015//glomerular visceral epithelial cell development"	--
ENSG00000171459	0	0	0	0	0	0	0	0	0	0	0	0	OR1L6	olfactory receptor family 1 subfamily L member 6 [Source:HGNC Symbol;Acc:HGNC:8218]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171462	1.567	2.458	2.682	2.018	2.87	2.743	51	80	67	48	78	65	DLK2	delta like non-canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:21113]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0042802//identical protein binding	GO:0045598//regulation of fat cell differentiation;GO:0045746//negative regulation of Notch signaling pathway	--
ENSG00000171466	4.855	3.219	3.517	4.501	4.099	4.575	440	368	292	262	298	284	ZNF562	zinc finger protein 562 [Source:HGNC Symbol;Acc:HGNC:25950]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171467	5.358	5.163	5.309	3.98	4.568	5.814	881	855	661	502	651	621	ZNF318	zinc finger protein 318 [Source:HGNC Symbol;Acc:HGNC:13578]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051321//meiotic cell cycle"	Others
ENSG00000171469	11.567	12.005	14.046	10.518	11.747	9.786	700	650	514	478	583	491	ZNF561	zinc finger protein 561 [Source:HGNC Symbol;Acc:HGNC:28684]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171475	10.227	11.596	10.595	11.489	11.764	11.451	1257	1307	966	1012	1176	1013	WIPF2	WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923]	Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko04144//Endocytosis;ko05135//Yersinia infection	K19475;K19475;K19475	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament	GO:0003779//actin binding;GO:0005515//protein binding	GO:0030048//actin filament-based movement	--
ENSG00000171476	2.008	2.568	0.405	0.072	0.101	0.066	48	62	7	1	2	1	HOPX	HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001829//trophectodermal cell differentiation;GO:0003166//bundle of His development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008016//regulation of heart contraction;GO:0016575//histone deacetylation;GO:0030154//cell differentiation;GO:0043393//regulation of protein binding;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0045596//negative regulation of cell differentiation;GO:0048286//lung alveolus development;GO:0051131//chaperone-mediated protein complex assembly;GO:0051155//positive regulation of striated muscle cell differentiation	Homeobox
ENSG00000171478	0	0	0	0	0	0	0	0	0	0	0	0	SPACA5B	sperm acrosome associated 5B [Source:HGNC Symbol;Acc:HGNC:19142]	-	-	-	-	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process	--
ENSG00000171481	0	0	0	0	0	0	0	0	0	0	0	0	OR1L3	olfactory receptor family 1 subfamily L member 3 [Source:HGNC Symbol;Acc:HGNC:8215]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171487	0	0	0	0	0	0	0	0	0	0	0	0	NLRP5	NLR family pyrin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21269]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005938//cell cortex;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0060473//cortical granule;GO:0106333//subcortical maternal complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015631//tubulin binding	GO:0006887//exocytosis;GO:0007015//actin filament organization;GO:0032879//regulation of localization;GO:0040019//positive regulation of embryonic development;GO:0051293//establishment of spindle localization;GO:0051302//regulation of cell division;GO:0051656//establishment of organelle localization;GO:0060471//cortical granule exocytosis	--
ENSG00000171488	6.388	5.613	6.355	5.546	6.343	7.217	950	839	698	611	797	781	LRRC8C	leucine rich repeat containing 8 VRAC subunit C [Source:HGNC Symbol;Acc:HGNC:25075]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034702//ion channel complex	GO:0005225//volume-sensitive anion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0015698//inorganic anion transport;GO:0015734//taurine transport;GO:0015810//aspartate transmembrane transport;GO:0034214//protein hexamerization;GO:0045444//fat cell differentiation;GO:0071470//cellular response to osmotic stress;GO:0098656//anion transmembrane transport;GO:0140361//cyclic-GMP-AMP transmembrane import across plasma membrane	--
ENSG00000171489	0	0	0	0	0	0	0	0	0	0	0	0	SPACA5	sperm acrosome associated 5 [Source:HGNC Symbol;Acc:HGNC:31353]	-	-	-	-	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process	--
ENSG00000171490	48.443	49.291	42.69	31.445	33.522	33.283	1954	1975	1242	948	1188	985	RSL1D1	ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24534]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0030686//90S preribosome	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0045296//cadherin binding;GO:0048027//mRNA 5'-UTR binding	GO:0000470//maturation of LSU-rRNA;GO:0001649//osteoblast differentiation;GO:0032880//regulation of protein localization;GO:0042981//regulation of apoptotic process;GO:2000772//regulation of cellular senescence	--
ENSG00000171492	12.896	14.711	11.408	10.121	11.084	15.784	888	811	562	538	635	746	LRRC8D	leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034702//ion channel complex	GO:0005225//volume-sensitive anion channel activity;GO:0005515//protein binding	GO:0001678//cellular glucose homeostasis;GO:0006811//ion transport;GO:0015698//inorganic anion transport;GO:0015734//taurine transport;GO:0015810//aspartate transmembrane transport;GO:0034214//protein hexamerization;GO:0071470//cellular response to osmotic stress;GO:0098656//anion transmembrane transport	--
ENSG00000171495	0	0	0	0	0	0	0	0	0	0	0	0	MROH2B	maestro heat like repeat family member 2B [Source:HGNC Symbol;Acc:HGNC:26857]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece	-	GO:0007283//spermatogenesis;GO:0010737//protein kinase A signaling;GO:0030154//cell differentiation	--
ENSG00000171496	0	0	0	0	0	0	0	0	0	0	0	0	OR1L8	olfactory receptor family 1 subfamily L member 8 [Source:HGNC Symbol;Acc:HGNC:15110]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171497	18.691	17.351	13.386	17.093	17.693	17.876	445.32	457.79	275.94	288.42	358.13	341.73	PPID	peptidylprolyl isomerase D [Source:HGNC Symbol;Acc:HGNC:9257]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Cell growth and death;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05131//Shigellosis;ko04217//Necroptosis;ko04218//Cellular senescence	K05864;K05864;K05864;K05864;K05864	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0030331//estrogen receptor binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0051879//Hsp90 protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0006915//apoptotic process;GO:0015031//protein transport;GO:0019076//viral release from host cell;GO:0034389//lipid droplet organization;GO:0043065//positive regulation of apoptotic process;GO:0045070//positive regulation of viral genome replication;GO:0050714//positive regulation of protein secretion;GO:0061077//chaperone-mediated protein folding;GO:0065003//protein-containing complex assembly;GO:0071492//cellular response to UV-A	--
ENSG00000171501	0	0	0	0	0	0	0	0	0	0	0	0	OR1N2	olfactory receptor family 1 subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:15111]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171502	0.08	0.147	0.306	0.086	0.192	0.291	10	21	32	9	23	30	COL24A1	collagen type XXIV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:20821]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization	--
ENSG00000171503	9.777	9.219	11.218	8.857	9.4	12.043	543.68	466.21	424.06	351.58	411.87	458.27	ETFDH	electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0031966//mitochondrial membrane	"GO:0004174//electron-transferring-flavoprotein dehydrogenase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0048038//quinone binding;GO:0048039//ubiquinone binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006979//response to oxidative stress;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase	--
ENSG00000171505	0	0	0	0	0	0	0	0	0	0	0	0	OR1N1	olfactory receptor family 1 subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:8221]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171509	0	0.045	0.074	0	0	0	0	2	2	0	0	0	RXFP1	relaxin family peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:19718]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K04306;K04306	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0042562//hormone binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007567//parturition;GO:0009755//hormone-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0060427//lung connective tissue development;GO:0060658//nipple morphogenesis	--
ENSG00000171517	0	0.014	0	0	0.017	0.02	0	1	0	0	1	1	LPAR3	lysophosphatidic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:14298]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway	K04294;K04294;K04294;K04294;K04294	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0070915//lysophosphatidic acid receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0010467//gene expression;GO:0019222//regulation of metabolic process;GO:0032060//bleb assembly;GO:0043410//positive regulation of MAPK cascade;GO:0048672//positive regulation of collateral sprouting"	--
ENSG00000171522	0.436	0.503	0.666	1.575	1.264	1.526	31	36	35	83	76	79	PTGER4	prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Sensory system;Endocrine system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko05165//Human papillomavirus infection;ko05163//Human cytomegalovirus infection;ko04750//Inflammatory mediator regulation of TRP channels;ko04924//Renin secretion	K04261;K04261;K04261;K04261;K04261;K04261	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004955//prostaglandin receptor activity;GO:0004957//prostaglandin E receptor activity;GO:0005515//protein binding	GO:0001818//negative regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007254//JNK cascade;GO:0009612//response to mechanical stimulus;GO:0030278//regulation of ossification;GO:0032496//response to lipopolysaccharide;GO:0033624//negative regulation of integrin activation;GO:0042093//T-helper cell differentiation;GO:0050728//negative regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0051492//regulation of stress fiber assembly;GO:0060348//bone development;GO:0070371//ERK1 and ERK2 cascade;GO:0071260//cellular response to mechanical stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:2000420//negative regulation of eosinophil extravasation	--
ENSG00000171530	60.238	65.288	74.361	65.66	59.276	79.682	828	899	756	668	690	795	TBCA	tubulin folding cofactor A [Source:HGNC Symbol;Acc:HGNC:11579]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0048487//beta-tubulin binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway	--
ENSG00000171532	0.016	0	0.086	0.064	0.038	0.066	1	0	4	3	2	3	NEUROD2	neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001662//behavioral fear response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008306//associative learning;GO:0016567//protein ubiquitination;GO:0021695//cerebellar cortex development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0031915//positive regulation of synaptic plasticity;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048666//neuron development;GO:0050850//positive regulation of calcium-mediated signaling;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0071257//cellular response to electrical stimulus;GO:0071277//cellular response to calcium ion;GO:0090128//regulation of synapse maturation;GO:0090129//positive regulation of synapse maturation;GO:2000297//negative regulation of synapse maturation"	bHLH
ENSG00000171533	4.955	6.285	5.805	6.576	5.77	4.428	315	346	201	245	257	179	MAP6	microtubule associated protein 6 [Source:HGNC Symbol;Acc:HGNC:6868]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005801//cis-Golgi network;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0032418//lysosome localization;GO:0048813//dendrite morphogenesis;GO:0050772//positive regulation of axonogenesis;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000171540	0	0	0	0	0	0	0	0	0	0	0	0	OTP	orthopedia homeobox [Source:HGNC Symbol;Acc:HGNC:8518]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0021879//forebrain neuron differentiation;GO:0021979//hypothalamus cell differentiation;GO:0021985//neurohypophysis development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation"	Homeobox
ENSG00000171551	0.072	0.117	0.084	0.068	0.06	0.029	2	7	3	3	3	1	ECEL1	endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0003016//respiratory system process;GO:0006508//proteolysis;GO:0007218//neuropeptide signaling pathway;GO:0016485//protein processing	--
ENSG00000171552	80.318	82.271	86.247	90.121	89.634	91.4	4322	4454	3424	3582	4030	3537	BCL2L1	BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Immune system;Signal transduction;Signal transduction;Cancer: specific types;Transport and catabolism;Infectious disease: viral;Cell growth and death;Infectious disease: parasitic;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Transport and catabolism;Drug resistance: antineoplastic;Cell growth and death;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05014//Amyotrophic lateral sclerosis;ko05012//Parkinson disease;ko05202//Transcriptional misregulation in cancer;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko04140//Autophagy - animal;ko05162//Measles;ko04210//Apoptosis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko04137//Mitophagy - animal;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04215//Apoptosis - multiple species	K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570;K04570	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0031966//mitochondrial membrane;GO:0045202//synapse;GO:0097136//Bcl-2 family protein complex;GO:0097143//PUMA-BCL-xl complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051434//BH3 domain binding	GO:0001541//ovarian follicle development;GO:0001701//in utero embryonic development;GO:0001836//release of cytochrome c from mitochondria;GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008637//apoptotic mitochondrial changes;GO:0009314//response to radiation;GO:0009566//fertilization;GO:0009605//response to external stimulus;GO:0009615//response to virus;GO:0010507//negative regulation of autophagy;GO:0012501//programmed cell death;GO:0019050//suppression by virus of host apoptotic process;GO:0032465//regulation of cytokinesis;GO:0034097//response to cytokine;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0046898//response to cycloheximide;GO:0046902//regulation of mitochondrial membrane permeability;GO:0051402//neuron apoptotic process;GO:0051607//defense response to virus;GO:0051881//regulation of mitochondrial membrane potential;GO:0070584//mitochondrion morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0071312//cellular response to alkaloid;GO:0071480//cellular response to gamma radiation;GO:0071839//apoptotic process in bone marrow cell;GO:0080135//regulation of cellular response to stress;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0097284//hepatocyte apoptotic process;GO:1900118//negative regulation of execution phase of apoptosis;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000811//negative regulation of anoikis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000171557	0.094	0	0	0	0.389	0.086	3	0	0	0	12	2	FGG	fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Infectious disease: bacterial;Immune system;Immune system	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko05150//Staphylococcus aureus infection;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K03905;K03905;K03905;K03905;K03905	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	"GO:0007160//cell-matrix adhesion;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0009306//protein secretion;GO:0030168//platelet activation;GO:0031639//plasminogen activation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034622//cellular protein-containing complex assembly;GO:0036345//platelet maturation;GO:0042730//fibrinolysis;GO:0045907//positive regulation of vasoconstriction;GO:0045921//positive regulation of exocytosis;GO:0050714//positive regulation of protein secretion;GO:0051258//protein polymerization;GO:0051592//response to calcium ion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:0090331//negative regulation of platelet aggregation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process"	--
ENSG00000171560	0	0	0	0	0	0	0	0	0	0	0	0	FGA	fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Immune system;Immune system	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K03903;K03903;K03903;K03903	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1903561//extracellular vesicle	GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007160//cell-matrix adhesion;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030168//platelet activation;GO:0031639//plasminogen activation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034622//cellular protein-containing complex assembly;GO:0042730//fibrinolysis;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0045907//positive regulation of vasoconstriction;GO:0045921//positive regulation of exocytosis;GO:0050714//positive regulation of protein secretion;GO:0051258//protein polymerization;GO:0051592//response to calcium ion;GO:0065003//protein-containing complex assembly;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0072377//blood coagulation, common pathway;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process"	--
ENSG00000171561	0	0	0	0	0	0	0	0	0	0	0	0	OR2AT4	olfactory receptor family 2 subfamily AT member 4 [Source:HGNC Symbol;Acc:HGNC:19620]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000171564	0	0	0	0	0.115	0	0	0	0	0	5	0	FGB	fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Immune system;Immune system;Immune system	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K03904;K03904;K03904;K03904	GO:0005576//extracellular region;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1903561//extracellular vesicle	GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0051087//chaperone binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0030168//platelet activation;GO:0031639//plasminogen activation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034622//cellular protein-containing complex assembly;GO:0042730//fibrinolysis;GO:0043152//induction of bacterial agglutination;GO:0044320//cellular response to leptin stimulus;GO:0045087//innate immune response;GO:0045907//positive regulation of vasoconstriction;GO:0045921//positive regulation of exocytosis;GO:0050714//positive regulation of protein secretion;GO:0051258//protein polymerization;GO:0051592//response to calcium ion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0071347//cellular response to interleukin-1;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process"	--
ENSG00000171566	17.293	19.436	17.012	14.545	15.094	18.894	718	761	562	429	536	535	PLRG1	pleiotropic regulator 1 [Source:HGNC Symbol;Acc:HGNC:9089]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12862	GO:0000974//Prp19 complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0034504//protein localization to nucleus;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000171570	0.142	0.114	0	0.269	0	0.165	8.15	6.62	0	11.47	0	6.92	RAB4B-EGLN2	RAB4B-EGLN2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44465]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005525//GTP binding	GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0032482//Rab protein signal transduction	--
ENSG00000171574	6.518	8.779	6.644	6.457	7.786	7.701	244	306	177	166	202	218	ZNF584	zinc finger protein 584 [Source:HGNC Symbol;Acc:HGNC:27318]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171587	0	0	0.061	0	0.032	0	0	0	5	0	3	0	DSCAM	DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005515//protein binding;GO:0098632//cell-cell adhesion mediator activity;GO:1990782//protein tyrosine kinase binding;GO:1990890//netrin receptor binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007162//negative regulation of cell adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007626//locomotory behavior;GO:0010842//retina layer formation;GO:0038007//netrin-activated signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0048699//generation of neurons;GO:0048813//dendrite morphogenesis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0060060//post-embryonic retina morphogenesis in camera-type eye;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0070593//dendrite self-avoidance	--
ENSG00000171595	0	0	0.066	0	0	0	0	0	2	0	0	0	DNAI2	dynein axonemal intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:18744]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K11143;K11143;K11143	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0009897//external side of plasma membrane;GO:0030286//dynein complex;GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0042995//cell projection;GO:0097729//9+2 motile cilium;GO:0120293//dynein axonemal particle	GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding	GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0007368//determination of left/right symmetry;GO:0030030//cell projection organization;GO:0036158//outer dynein arm assembly;GO:0060271//cilium assembly	--
ENSG00000171596	0.03	0.223	0.162	0.182	0.177	0.144	2	15	8	9	10	7	NMUR1	neuromedin U receptor 1 [Source:HGNC Symbol;Acc:HGNC:4518]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05052	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001607//neuromedin U receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008188//neuropeptide receptor activity;GO:0042924//neuromedin U binding	GO:0006816//calcium ion transport;GO:0006821//chloride transport;GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007218//neuropeptide signaling pathway;GO:0019722//calcium-mediated signaling;GO:0048016//inositol phosphate-mediated signaling	--
ENSG00000171603	206.67	224.375	221.199	192.651	202.969	192.778	18399	20103	14510	12705	15235	12513	CLSTN1	calsyntenin 1 [Source:HGNC Symbol;Acc:HGNC:17447]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098845//postsynaptic endosome;GO:0098978//glutamatergic synapse	GO:0001540//amyloid-beta binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0042988//X11-like protein binding	GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050806//positive regulation of synaptic transmission;GO:0051965//positive regulation of synapse assembly;GO:0090128//regulation of synapse maturation;GO:0098969//neurotransmitter receptor transport to postsynaptic membrane;GO:0099003//vesicle-mediated transport in synapse	--
ENSG00000171604	94.87	92.44	90.26	75.728	90.238	81.816	4188	4116	2944	2552	3278	2630	CXXC5	CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000171606	8.211	9.516	8.211	10.244	6.507	10.219	419	474	323	345	303	360	ZNF274	zinc finger protein 274 [Source:HGNC Symbol;Acc:HGNC:13068]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12458	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:1900112//regulation of histone H3-K9 trimethylation"	zf-C2H2
ENSG00000171608	1.995	2.047	2.11	2.288	2.351	2.249	224	231	174	186	223	184	PIK3CD	"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [Source:HGNC Symbol;Acc:HGNC:8977]"	Metabolism;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Global and overview maps;Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Carbohydrate metabolism;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko01100//Metabolic pathways;ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko00562//Inositol phosphate metabolism;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922;K00922	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0016020//membrane"	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016740//transferase activity;GO:0035004//phosphatidylinositol 3-kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0052742//phosphatidylinositol kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0001779//natural killer cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002551//mast cell chemotaxis;GO:0002679//respiratory burst involved in defense response;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010818//T cell chemotaxis;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0030101//natural killer cell activation;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0035747//natural killer cell chemotaxis;GO:0035754//B cell chemotaxis;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0043303//mast cell degranulation;GO:0045087//innate immune response;GO:0045766//positive regulation of angiogenesis;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0060374//mast cell differentiation;GO:0072672//neutrophil extravasation;GO:1905278//positive regulation of epithelial tube formation	--
ENSG00000171611	0	0	0	0	0	0	0	0	0	0	0	0	PTCRA	pre T cell antigen receptor alpha [Source:HGNC Symbol;Acc:HGNC:21290]	Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction	ko05202//Transcriptional misregulation in cancer;ko04330//Notch signaling pathway	K06056;K06056	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0070244//negative regulation of thymocyte apoptotic process	--
ENSG00000171612	4.74	4.145	5.016	4.85	5.241	5.623	380	334	297	288	355	328	SLC25A33	solute carrier family 25 member 33 [Source:HGNC Symbol;Acc:HGNC:29681]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0015218//pyrimidine nucleotide transmembrane transporter activity	GO:0000002//mitochondrial genome maintenance;GO:0002082//regulation of oxidative phosphorylation;GO:0006390//mitochondrial transcription;GO:0006864//pyrimidine nucleotide transport;GO:0007005//mitochondrion organization;GO:0008284//positive regulation of cell population proliferation;GO:0030307//positive regulation of cell growth;GO:0031930//mitochondria-nucleus signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0051881//regulation of mitochondrial membrane potential;GO:1903426//regulation of reactive oxygen species biosynthetic process;GO:1990314//cellular response to insulin-like growth factor stimulus;GO:1990519//pyrimidine nucleotide import into mitochondrion	--
ENSG00000171617	5.912	5.645	3.802	7.975	7.672	5.641	558	578	283	577	610	427	ENC1	ectodermal-neural cortex 1 [Source:HGNC Symbol;Acc:HGNC:3345]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016363//nuclear matrix;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0043025//neuronal cell body	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:0010976//positive regulation of neuron projection development;GO:0016567//protein ubiquitination;GO:0017148//negative regulation of translation	--
ENSG00000171621	16.246	16.293	14.496	14.811	16.187	14.916	856	814	581	564	692	585	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:30628]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000171631	0.403	0.753	0.279	0.469	0.62	0.478	18	31	12	18	21	17	P2RY6	pyrimidinergic receptor P2Y6 [Source:HGNC Symbol;Acc:HGNC:8543]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04272	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0001621//G protein-coupled ADP receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0045028//G protein-coupled purinergic nucleotide receptor activity;GO:0045029//G protein-coupled UDP receptor activity;GO:0045030//G protein-coupled UTP receptor activity	"GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030321//transepithelial chloride transport;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071415//cellular response to purine-containing compound;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1905835//cellular response to pyrimidine ribonucleotide"	--
ENSG00000171634	8.215	6.132	5.702	4.125	5.325	5.002	1202	839	503	408	605	450	BPTF	bromodomain PHD finger transcription factor [Source:HGNC Symbol;Acc:HGNC:3581]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016589//NURF complex;GO:0070062//extracellular exosome;GO:1904949//ATPase complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0035064//methylated histone binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001892//embryonic placenta development;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0007492//endoderm development;GO:0009952//anterior/posterior pattern specification;GO:0042766//nucleosome mobilization;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000171643	0	0	0	0	0	0	0	0	0	0	0	0	S100Z	S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0008150//biological_process	--
ENSG00000171649	4.063	4.012	3.016	2.406	3.584	4.497	257	265	166	117	198	182	ZIK1	zinc finger protein interacting with K protein 1 [Source:HGNC Symbol;Acc:HGNC:33104]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171657	0	0	0	0	0	0	0	0	0	0	0	0	GPR82	G protein-coupled receptor 82 [Source:HGNC Symbol;Acc:HGNC:4533]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000171659	0.029	0	0	0	0	0	1	0	0	0	0	0	GPR34	G protein-coupled receptor 34 [Source:HGNC Symbol;Acc:HGNC:4490]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway	--
ENSG00000171680	5.383	4.432	3.682	4.451	4.63	5.266	304	270	215	186	258	222	PLEKHG5	pleckstrin homology and RhoGEF domain containing G5 [Source:HGNC Symbol;Acc:HGNC:29105]	Human Diseases	Cancer: overview	ko05200//Pathways in cancer	K19464	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007266//Rho protein signal transduction;GO:0035767//endothelial cell chemotaxis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043542//endothelial cell migration;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000171681	18.227	16.354	14.341	10.259	13.373	12.756	2654	2281	1528	1123	1632	1382	ATF7IP	activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003712//transcription coregulator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0031647//regulation of protein stability;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045898//regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0050821//protein stabilization;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly"	--
ENSG00000171695	0.059	0.117	0	0.225	0.131	0	1	2	0	3	2	0	LKAAEAR1	LKAAEAR motif containing 1 [Source:HGNC Symbol;Acc:HGNC:33718]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000171700	1.903	1.715	1.427	2.414	1.89	2.476	62	54	33	56	50	58	RGS19	regulator of G protein signaling 19 [Source:HGNC Symbol;Acc:HGNC:13735]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0045121//membrane raft	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005515//protein binding	GO:0006914//autophagy;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0009968//negative regulation of signal transduction;GO:0045471//response to ethanol	--
ENSG00000171703	19.354	19.814	20.371	25.544	21.601	19.801	457	476	364	446	431	339	TCEA2	transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0008023//transcription elongation factor complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006354//DNA-templated transcription, elongation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006414//translational elongation;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000171711	0	0	0	0	0	0	0	0	0	0	0	0	DEFB4A	defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Immune system	ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection;ko04657//IL-17 signaling pathway	K21100;K21100;K21100	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0005515//protein binding;GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000171714	7.524	5.214	5.439	4.568	5.384	6.371	1058	733	567	477	640	649	ANO5	anoctamin 5 [Source:HGNC Symbol;Acc:HGNC:27337]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0046983//protein dimerization activity	GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000171720	23.234	25.052	25.888	25.513	22.932	23.403	895	883	761	702	720	643	HDAC3	histone deacetylase 3 [Source:HGNC Symbol;Acc:HGNC:4854]	Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Immune system;Cancer: overview;Substance dependence;Endocrine system	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism;ko04919//Thyroid hormone signaling pathway	K11404;K11404;K11404;K11404	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0017053//transcription repressor complex;GO:0072686//mitotic spindle	GO:0001222//transcription corepressor binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030332//cyclin binding;GO:0033558//protein deacetylase activity;GO:0042826//histone deacetylase binding;GO:0051059//NF-kappaB binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001934//positive regulation of protein phosphorylation;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006476//protein deacetylation;GO:0016575//histone deacetylation;GO:0031398//positive regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032008//positive regulation of TOR signaling;GO:0032922//circadian regulation of gene expression;GO:0042307//positive regulation of protein import into nucleus;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0048511//rhythmic process;GO:0051225//spindle assembly;GO:0071498//cellular response to fluid shear stress;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000171722	0.114	0	0.039	0.192	0.135	0.039	4	0	1	5	4	1	SPATA46	spermatogenesis associated 46 [Source:HGNC Symbol;Acc:HGNC:27648]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0009566//fertilization;GO:0030154//cell differentiation	--
ENSG00000171723	3.767	4.232	4.313	5.554	4.662	4.678	276	311	235	261	284	240	GPHN	gephyrin [Source:HGNC Symbol;Acc:HGNC:15465]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Nervous system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04727//GABAergic synapse;ko00790//Folate biosynthesis	K15376;K15376;K15376	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097060//synaptic membrane;GO:0099144//anchored component of synaptic membrane;GO:0099572//postsynaptic specialization;GO:0099634//postsynaptic specialization membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008940//nitrate reductase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043546//molybdopterin cofactor binding;GO:0046872//metal ion binding;GO:0061598//molybdopterin adenylyltransferase activity;GO:0061599//molybdopterin molybdotransferase activity	GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0007529//establishment of synaptic specificity at neuromuscular junction;GO:0008152//metabolic process;GO:0010038//response to metal ion;GO:0018315//molybdenum incorporation into molybdenum-molybdopterin complex;GO:0032324//molybdopterin cofactor biosynthetic process;GO:0072579//glycine receptor clustering;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping	--
ENSG00000171724	144.774	147.779	173.43	175.137	179.052	176.899	11384	11680	10072	10201	11895	10121	VAT1L	vesicle amine transport 1 like [Source:HGNC Symbol;Acc:HGNC:29315]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity	-	--
ENSG00000171729	59.709	64.783	47.536	36.107	38.387	35.021	2285	2525	1362	1039	1264	984	TMEM51	transmembrane protein 51 [Source:HGNC Symbol;Acc:HGNC:25488]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000171735	14.206	15.46	16.898	16.123	17.363	15.725	173	187	148	136	166	131	CAMTA1	calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0035307//positive regulation of protein dephosphorylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050885//neuromuscular process controlling balance;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	CG-1
ENSG00000171747	0	0	0.058	0	0	0.059	0	0	1	0	0	1	LGALS4	galectin 4 [Source:HGNC Symbol;Acc:HGNC:6565]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	GO:0007155//cell adhesion	--
ENSG00000171757	1.091	0.667	0.732	0.656	0.803	0.426	36	29	22	24	26	14	LRRC34	leucine rich repeat containing 34 [Source:HGNC Symbol;Acc:HGNC:28408]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0030154//cell differentiation	--
ENSG00000171759	0.288	0.243	0.695	0.285	0.147	0.728	11	18	7	9	9	17	PAH	phenylalanine hydroxylase [Source:HGNC Symbol;Acc:HGNC:8582]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Metabolism of cofactors and vitamins;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00790//Folate biosynthesis;ko00360//Phenylalanine metabolism;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K00500;K00500;K00500;K00500;K00500	GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004497//monooxygenase activity;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046872//metal ion binding"	"GO:0006559//L-phenylalanine catabolic process;GO:0006571//tyrosine biosynthetic process;GO:0008152//metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009072//aromatic amino acid family metabolic process;GO:0019293//tyrosine biosynthetic process, by oxidation of phenylalanine;GO:0042136//neurotransmitter biosynthetic process;GO:0042423//catecholamine biosynthetic process"	--
ENSG00000171763	1.854	2.316	2.736	1.965	1.878	2.305	98	123	98	66	84	78	SPATA5L1	spermatogenesis associated 5 like 1 [Source:HGNC Symbol;Acc:HGNC:28762]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000171766	1.815	1.436	1.68	2.057	2.701	2.017	81	70	56	65	97	61	GATM	glycine amidinotransferase [Source:HGNC Symbol;Acc:HGNC:4175]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00260//Glycine, serine and threonine metabolism"	K00613;K00613;K00613	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015067//amidinotransferase activity;GO:0015068//glycine amidinotransferase activity;GO:0016740//transferase activity	GO:0006600//creatine metabolic process;GO:0006601//creatine biosynthetic process;GO:0007611//learning or memory;GO:0014889//muscle atrophy;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000171772	0.115	0	0	0	0	0	3	0	0	0	0	0	SYCE1	synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0000801//central element;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007130//synaptonemal complex assembly;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0070193//synaptonemal complex organization	--
ENSG00000171773	0	0	0	0	0	0	0	0	0	0	0	0	NXNL1	nucleoredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:25179]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0042995//cell projection	GO:0005515//protein binding	GO:0045494//photoreceptor cell maintenance	--
ENSG00000171777	0	0	0	0	0	0	0	0	0	0	0	0	RASGRP4	RAS guanyl releasing protein 4 [Source:HGNC Symbol;Acc:HGNC:18958]	Human Diseases;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway	K12363;K12363;K12363	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019992//diacylglycerol binding;GO:0030742//GTP-dependent protein binding;GO:0046872//metal ion binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0008283//cell population proliferation;GO:0009991//response to extracellular stimulus;GO:0030099//myeloid cell differentiation;GO:0030154//cell differentiation;GO:0043547//positive regulation of GTPase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus	--
ENSG00000171786	0.019	0.019	0.026	0.025	0.045	0.026	1	1	1	1	2	1	NHLH1	nescient helix-loop-helix 1 [Source:HGNC Symbol;Acc:HGNC:7817]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	bHLH
ENSG00000171790	0.363	0.268	0.045	0.191	0.314	0.077	9	13	3	9	4	5	SLFNL1	schlafen like 1 [Source:HGNC Symbol;Acc:HGNC:26313]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000171791	2.747	2.24	2.643	3.05	3.149	3.66	393	319	275	328	373	371	BCL2	BCL2 apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:990]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Genetic Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes	"Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Cellular community - eukaryotes;Cancer: overview;Immune system;Signal transduction;Cancer: overview;Folding, sorting and degradation;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Circulatory system;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cardiovascular disease;Endocrine system;Nervous system;Signal transduction;Signal transduction;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Drug resistance: antineoplastic;Cell growth and death;Signal transduction;Cell growth and death"	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05014//Amyotrophic lateral sclerosis;ko05169//Epstein-Barr virus infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04141//Protein processing in endoplasmic reticulum;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko04140//Autophagy - animal;ko04261//Adrenergic signaling in cardiomyocytes;ko05226//Gastric cancer;ko05162//Measles;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04066//HIF-1 signaling pathway;ko04725//Cholinergic synapse;ko05145//Toxoplasmosis;ko04928//Parathyroid hormone synthesis, secretion and action;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko04340//Hedgehog signaling pathway;ko04215//Apoptosis - multiple species"	K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161;K02161	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0043209//myelin sheath;GO:0046930//pore complex	GO:0002020//protease binding;GO:0005515//protein binding;GO:0015267//channel activity;GO:0016248//channel inhibitor activity;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0051434//BH3 domain binding;GO:0051721//protein phosphatase 2A binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000209//protein polyubiquitination;GO:0000902//cell morphogenesis;GO:0001503//ossification;GO:0001541//ovarian follicle development;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001662//behavioral fear response;GO:0001776//leukocyte homeostasis;GO:0001782//B cell homeostasis;GO:0001822//kidney development;GO:0001836//release of cytochrome c from mitochondria;GO:0001952//regulation of cell-matrix adhesion;GO:0002260//lymphocyte homeostasis;GO:0002320//lymphoid progenitor cell differentiation;GO:0002326//B cell lineage commitment;GO:0002360//T cell lineage commitment;GO:0002520//immune system development;GO:0002931//response to ischemia;GO:0003014//renal system process;GO:0006470//protein dephosphorylation;GO:0006582//melanin metabolic process;GO:0006808//regulation of nitrogen utilization;GO:0006874//cellular calcium ion homeostasis;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007015//actin filament organization;GO:0007409//axonogenesis;GO:0007565//female pregnancy;GO:0007569//cell aging;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0008637//apoptotic mitochondrial changes;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009605//response to external stimulus;GO:0009636//response to toxic substance;GO:0009791//post-embryonic development;GO:0009887//animal organ morphogenesis;GO:0010039//response to iron ion;GO:0010224//response to UV-B;GO:0010332//response to gamma radiation;GO:0010468//regulation of gene expression;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0010559//regulation of glycoprotein biosynthetic process;GO:0012501//programmed cell death;GO:0014031//mesenchymal cell development;GO:0014042//positive regulation of neuron maturation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0021747//cochlear nucleus development;GO:0022612//gland morphogenesis;GO:0022898//regulation of transmembrane transporter activity;GO:0030097//hemopoiesis;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030279//negative regulation of ossification;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0030318//melanocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0031069//hair follicle morphogenesis;GO:0031103//axon regeneration;GO:0031647//regulation of protein stability;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032835//glomerulus development;GO:0032848//negative regulation of cellular pH reduction;GO:0032880//regulation of protein localization;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0033077//T cell differentiation in thymus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033689//negative regulation of osteoblast proliferation;GO:0034097//response to cytokine;GO:0035094//response to nicotine;GO:0035265//organ growth;GO:0040008//regulation of growth;GO:0040018//positive regulation of multicellular organism growth;GO:0042100//B cell proliferation;GO:0042149//cellular response to glucose starvation;GO:0042542//response to hydrogen peroxide;GO:0042981//regulation of apoptotic process;GO:0043029//T cell homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043067//regulation of programmed cell death;GO:0043085//positive regulation of catalytic activity;GO:0043375//CD8-positive, alpha-beta T cell lineage commitment;GO:0043473//pigmentation;GO:0043524//negative regulation of neuron apoptotic process;GO:0043583//ear development;GO:0045069//regulation of viral genome replication;GO:0045636//positive regulation of melanocyte differentiation;GO:0045930//negative regulation of mitotic cell cycle;GO:0046671//negative regulation of retinal cell programmed cell death;GO:0046902//regulation of mitochondrial membrane permeability;GO:0048041//focal adhesion assembly;GO:0048066//developmental pigmentation;GO:0048070//regulation of developmental pigmentation;GO:0048087//positive regulation of developmental pigmentation;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048545//response to steroid hormone;GO:0048546//digestive tract morphogenesis;GO:0048589//developmental growth;GO:0048599//oocyte development;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0048753//pigment granule organization;GO:0048873//homeostasis of number of cells within a tissue;GO:0050790//regulation of catalytic activity;GO:0050853//B cell receptor signaling pathway;GO:0051384//response to glucocorticoid;GO:0051402//neuron apoptotic process;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0051881//regulation of mitochondrial membrane potential;GO:0051902//negative regulation of mitochondrial depolarization;GO:0051924//regulation of calcium ion transport;GO:0055085//transmembrane transport;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071310//cellular response to organic substance;GO:0071456//cellular response to hypoxia;GO:0072593//reactive oxygen species metabolic process;GO:0080135//regulation of cellular response to stress;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0098609//cell-cell adhesion;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2000811//negative regulation of anoikis;GO:2001234//negative regulation of apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000171792	10.814	10.535	9.371	9.028	9.202	10.481	376	375	274	243	308	301	RHNO1	RAD9-HUS1-RAD1 interacting nuclear orphan 1 [Source:HGNC Symbol;Acc:HGNC:28206]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0000725//recombinational repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0034644//cellular response to UV;GO:0070318//positive regulation of G0 to G1 transition;GO:0071479//cellular response to ionizing radiation	--
ENSG00000171793	7.309	6.919	7.615	5.931	5.892	7.265	423	419	338	243	296	292	CTPS1	CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K01937;K01937	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0097268//cytoophidium	GO:0000166//nucleotide binding;GO:0003883//CTP synthase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0042098//T cell proliferation;GO:0042100//B cell proliferation;GO:0044210//'de novo' CTP biosynthetic process	--
ENSG00000171794	0	0	0	0	0	0	0	0	0	0	0	0	UTF1	undifferentiated embryonic cell transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12634]	-	-	-	-	GO:0005634//nucleus	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008584//male gonad development;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000171798	3.042	2.886	3.239	3.943	4.088	3.102	388	346	263	328	365	278	KNDC1	kinase non-catalytic C-lobe domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29374]	-	-	-	-	GO:0005575//cellular_component;GO:0030425//dendrite;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0003674//molecular_function;GO:0005085//guanyl-nucleotide exchange factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0008150//biological_process;GO:0021707//cerebellar granule cell differentiation;GO:0048814//regulation of dendrite morphogenesis;GO:0050773//regulation of dendrite development;GO:0050790//regulation of catalytic activity	--
ENSG00000171804	0	0	0	0	0	0	0	0	0	0	0	0	WDR87	WD repeat domain 87 [Source:HGNC Symbol;Acc:HGNC:29934]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000171806	3.335	3.297	2.762	2.582	2.246	3.386	95	92	52	42	50	65	METTL18	methyltransferase like 18 [Source:HGNC Symbol;Acc:HGNC:28793]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018064//protein-L-histidine N-tele-methyltransferase activity;GO:0031072//heat shock protein binding	"GO:0006417//regulation of translation;GO:0018026//peptidyl-lysine monomethylation;GO:0032259//methylation;GO:0042038//peptidyl-histidine methylation, to form tele-methylhistidine;GO:0090069//regulation of ribosome biogenesis;GO:2000232//regulation of rRNA processing"	--
ENSG00000171811	1.032	1.162	1.089	0.684	0.43	0.542	87	89	56	45	41	35	CFAP46	cilia and flagella associated protein 46 [Source:HGNC Symbol;Acc:HGNC:25247]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection	-	GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0060294//cilium movement involved in cell motility	--
ENSG00000171812	100.532	95.806	123.466	137.722	130.092	160.649	9736	9313	8831	9863	10638	11320	COL8A2	collagen type VIII alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2216]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K23455	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0048593//camera-type eye morphogenesis;GO:0050673//epithelial cell proliferation;GO:0098609//cell-cell adhesion	--
ENSG00000171813	4.884	5.038	5.243	5.227	5.167	6.193	259	256	207	203	229	235	PWWP2B	PWWP domain containing 2B [Source:HGNC Symbol;Acc:HGNC:25150]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0120325//NuRD complex binding	GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0035067//negative regulation of histone acetylation;GO:0120161//regulation of cold-induced thermogenesis;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:2000616//negative regulation of histone H3-K9 acetylation	--
ENSG00000171815	0.018	0.042	0.106	0.016	0.029	0.058	3	7	13	2	4	7	PCDHB1	protocadherin beta 1 [Source:HGNC Symbol;Acc:HGNC:8680]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000171817	1.66	1.69	1.067	1.099	1.339	1.334	109	95	45	51	58	50	ZNF540	zinc finger protein 540 [Source:HGNC Symbol;Acc:HGNC:25331]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0017148//negative regulation of translation;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000171819	29.33	33.019	15.938	34.182	36.256	26.814	1353	1531	543	1168	1413	900	ANGPTL7	angiopoietin like 7 [Source:HGNC Symbol;Acc:HGNC:24078]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006979//response to oxidative stress;GO:1901346//negative regulation of vasculature development involved in avascular cornea development in camera-type eye;GO:1903053//regulation of extracellular matrix organization	--
ENSG00000171823	3.148	2.79	3.358	3.065	3.071	5.139	165	147	130	119	136	196	FBXL14	F-box and leucine rich repeat protein 14 [Source:HGNC Symbol;Acc:HGNC:28624]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000171824	15.243	16.846	13.868	10.429	13.634	14.29	884	982	594	448	668	603	EXOSC10	exosome component 10 [Source:HGNC Symbol;Acc:HGNC:9138]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12591	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0035327//transcriptionally active chromatin;GO:0101019//nucleolar exosome (RNase complex)	GO:0000166//nucleotide binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004532//exoribonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0070034//telomerase RNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000460//maturation of 5.8S rRNA;GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0044237//cellular metabolic process;GO:0071028//nuclear mRNA surveillance;GO:0071034//CUT catabolic process;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0071036//nuclear polyadenylation-dependent snoRNA catabolic process;GO:0071037//nuclear polyadenylation-dependent snRNA catabolic process;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process;GO:0071039//nuclear polyadenylation-dependent CUT catabolic process;GO:0071040//nuclear polyadenylation-dependent antisense transcript catabolic process;GO:0071044//histone mRNA catabolic process;GO:0071048//nuclear retention of unspliced pre-mRNA at the site of transcription;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:1904872//regulation of telomerase RNA localization to Cajal body"	--
ENSG00000171827	2.554	1.552	2.279	1.726	2.221	2.223	199	117	105	92	111	93	ZNF570	zinc finger protein 570 [Source:HGNC Symbol;Acc:HGNC:26416]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171840	0.061	0.133	0	0	0	0	1	2	0	0	0	0	NINJ2	ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007399//nervous system development;GO:0042246//tissue regeneration	--
ENSG00000171843	2.538	2.037	1.158	1.605	1.817	2.046	144	106	48	62	77	83	MLLT3	MLLT3 super elongation complex subunit [Source:HGNC Symbol;Acc:HGNC:7136]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15187	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0008023//transcription elongation factor complex;GO:0032783//super elongation complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0070577//lysine-acetylated histone binding;GO:0140030//modification-dependent protein binding	"GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007379//segment specification;GO:0009952//anterior/posterior pattern specification;GO:0010467//gene expression;GO:0016573//histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060218//hematopoietic stem cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1902275//regulation of chromatin organization;GO:2000035//regulation of stem cell division;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000171847	0	0.081	0.028	0	0	0	0	1	1	0	0	0	FAM90A1	family with sequence similarity 90 member A1 [Source:HGNC Symbol;Acc:HGNC:25526]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000171848	0.37	0.568	0.461	0.699	0.806	0.874	25	37	23	35	46	43	RRM2	ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]	Metabolism;Metabolism;Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Cell growth and death;Metabolism of other amino acids;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko04115//p53 signaling pathway;ko00480//Glutathione metabolism;ko00240//Pyrimidine metabolism	K10808;K10808;K10808;K10808;K10808;K10808	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005971//ribonucleoside-diphosphate reductase complex	"GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0005515//protein binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	GO:0001824//blastocyst development;GO:0006260//DNA replication;GO:0009185//ribonucleoside diphosphate metabolic process;GO:0009262//deoxyribonucleotide metabolic process;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0009265//2'-deoxyribonucleotide biosynthetic process;GO:0051290//protein heterotetramerization;GO:0055086//nucleobase-containing small molecule metabolic process;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000171853	16.172	16.253	20.438	16.804	17.381	17.508	785	788	702	631	693	639	TRAPPC12	trafficking protein particle complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:24284]	-	-	-	-	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0048471//perinuclear region of cytoplasm;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0016192//vesicle-mediated transport;GO:0048208//COPII vesicle coating;GO:0051310//metaphase plate congression;GO:0090234//regulation of kinetochore assembly;GO:0099022//vesicle tethering;GO:1905342//positive regulation of protein localization to kinetochore	--
ENSG00000171855	0	0	0	0	0	0	0	0	0	0	0	0	IFNB1	interferon beta 1 [Source:HGNC Symbol;Acc:HGNC:5434]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Development and regeneration;Signal transduction;Infectious disease: parasitic;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415;K05415	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding;GO:0008811//chloramphenicol O-acetyltransferase activity	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002312//B cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030101//natural killer cell activation;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0035458//cellular response to interferon-beta;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0045071//negative regulation of viral genome replication;GO:0045089//positive regulation of innate immune response;GO:0045343//regulation of MHC class I biosynthetic process;GO:0045581//negative regulation of T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0071360//cellular response to exogenous dsRNA;GO:0098586//cellular response to virus;GO:2000552//negative regulation of T-helper 2 cell cytokine production;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000171858	63.371	55.538	58.168	62.142	46.629	55.726	474	418	321	344	295	304	RPS21	ribosomal protein S21 [Source:HGNC Symbol;Acc:HGNC:10409]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02971;K02971	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0042788//polysomal ribosome;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0047485//protein N-terminus binding	"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181//cytoplasmic translation;GO:0006412//translation"	--
ENSG00000171860	0.014	0	0.019	0.019	0.066	0	1	0	1	1	4	0	C3AR1	complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades	K04009;K04009;K04009;K04009;K04009	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane	GO:0004875//complement receptor activity;GO:0004876//complement component C3a receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0002430//complement receptor mediated signaling pathway;GO:0002684//positive regulation of immune system process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008015//blood circulation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010759//positive regulation of macrophage chemotaxis;GO:0045766//positive regulation of angiogenesis;GO:0048584//positive regulation of response to stimulus;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis	--
ENSG00000171861	5.73	6.107	7.074	6.081	6.073	6.465	192	204	174	151	184	160	MRM3	mitochondrial rRNA methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:18485]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0070039//rRNA (guanosine-2'-O-)-methyltransferase activity	GO:0000451//rRNA 2'-O-methylation;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0032259//methylation	--
ENSG00000171862	27.425	24.596	19.708	17.562	19.143	17.588	2767	2377	1506	1329	1529	1322	PTEN	phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588]	Metabolism;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Cellular Processes;Human Diseases	Global and overview maps;Cancer: overview;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Cellular community - eukaryotes;Cancer: overview;Cancer: specific types;Signal transduction;Cell growth and death;Transport and catabolism;Cancer: specific types;Signal transduction;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Signal transduction;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview;Carbohydrate metabolism;Cell growth and death;Cancer: specific types	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko05224//Breast cancer;ko04068//FoxO signaling pathway;ko04071//Sphingolipid signaling pathway;ko04931//Insulin resistance;ko05215//Prostate cancer;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05222//Small cell lung cancer;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko05230//Central carbon metabolism in cancer;ko00562//Inositol phosphate metabolism;ko04115//p53 signaling pathway;ko05213//Endometrial cancer	K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110;K01110	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016324//apical plasma membrane;GO:0016605//PML body;GO:0035749//myelin sheath adaxonal region;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043220//Schmidt-Lanterman incisure;GO:0045202//synapse	"GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0010997//anaphase-promoting complex binding;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0051717//inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity;GO:0051800//phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity;GO:1990381//ubiquitin-specific protease binding"	"GO:0001525//angiogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0002902//regulation of B cell apoptotic process;GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006915//apoptotic process;GO:0007270//neuron-neuron synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0007417//central nervous system development;GO:0007507//heart development;GO:0007611//learning or memory;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010975//regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0016477//cell migration;GO:0021542//dentate gyrus development;GO:0021955//central nervous system neuron axonogenesis;GO:0030336//negative regulation of cell migration;GO:0030534//adult behavior;GO:0031642//negative regulation of myelination;GO:0031647//regulation of protein stability;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0032286//central nervous system myelin maintenance;GO:0032535//regulation of cellular component size;GO:0033032//regulation of myeloid cell apoptotic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0033555//multicellular organismal response to stress;GO:0035176//social behavior;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0036294//cellular response to decreased oxygen levels;GO:0042711//maternal behavior;GO:0043066//negative regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0043542//endothelial cell migration;GO:0045475//locomotor rhythm;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045792//negative regulation of cell size;GO:0046621//negative regulation of organ growth;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048679//regulation of axon regeneration;GO:0048681//negative regulation of axon regeneration;GO:0048738//cardiac muscle tissue development;GO:0048853//forebrain morphogenesis;GO:0048854//brain morphogenesis;GO:0048870//cell motility;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050771//negative regulation of axonogenesis;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051548//negative regulation of keratinocyte migration;GO:0051726//regulation of cell cycle;GO:0051895//negative regulation of focal adhesion assembly;GO:0051896//regulation of protein kinase B signaling;GO:0051898//negative regulation of protein kinase B signaling;GO:0060024//rhythmic synaptic transmission;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0060074//synapse maturation;GO:0060134//prepulse inhibition;GO:0060179//male mating behavior;GO:0060291//long-term synaptic potentiation;GO:0060341//regulation of cellular localization;GO:0060736//prostate gland growth;GO:0060997//dendritic spine morphogenesis;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071257//cellular response to electrical stimulus;GO:0071456//cellular response to hypoxia;GO:0090071//negative regulation of ribosome biogenesis;GO:0090344//negative regulation of cell aging;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0097105//presynaptic membrane assembly;GO:0097107//postsynaptic density assembly;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:1903690//negative regulation of wound healing, spreading of epidermal cells;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000808//negative regulation of synaptic vesicle clustering;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000171863	333.779	345.457	336.355	316.047	286.807	277.118	5062	5271	3774	3555	3675	3063	RPS7	ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02993;K02993	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0032040//small-subunit processome;GO:0032991//protein-containing complex;GO:0045202//synapse;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0048027//mRNA 5'-UTR binding;GO:1990948//ubiquitin ligase inhibitor activity	GO:0001843//neural tube closure;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0042274//ribosomal small subunit biogenesis;GO:0050821//protein stabilization;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1904667//negative regulation of ubiquitin protein ligase activity;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000171864	0.036	0.012	0.033	0	0.014	0	3	1	2	0	1	0	PRND	prion like protein doppel [Source:HGNC Symbol;Acc:HGNC:15748]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006878//cellular copper ion homeostasis;GO:0007338//single fertilization;GO:0007340//acrosome reaction;GO:0051260//protein homooligomerization	--
ENSG00000171865	6.367	5.817	6.088	5.879	6.563	6.575	698.52	641.45	493.26	477.76	572.96	513.88	RNASEH1	ribonuclease H1 [Source:HGNC Symbol;Acc:HGNC:18466]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K03469	GO:0005737//cytoplasm	GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0004540//ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006401//RNA catabolic process;GO:0043137//DNA replication, removal of RNA primer;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000171867	200.891	194.979	202.105	183.179	180.284	208.584	10172	9941	7573	6871	7726	7691	PRNP	prion protein [Source:HGNC Symbol;Acc:HGNC:9449]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05020//Prion disease;ko04216//Ferroptosis	K05634;K05634;K05634	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016234//inclusion body;GO:0019898//extrinsic component of membrane;GO:0030425//dendrite;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0031965//nuclear membrane;GO:0043195//terminal bouton;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0098794//postsynapse	GO:0001540//amyloid-beta binding;GO:0002020//protease binding;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0005539//glycosaminoglycan binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0043008//ATP-dependent protein binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:1903135//cupric ion binding;GO:1903136//cuprous ion binding	GO:0001933//negative regulation of protein phosphorylation;GO:0006878//cellular copper ion homeostasis;GO:0006979//response to oxidative stress;GO:0007049//cell cycle;GO:0007611//learning or memory;GO:0007616//long-term memory;GO:0010942//positive regulation of cell death;GO:0010951//negative regulation of endopeptidase activity;GO:0010955//negative regulation of protein processing;GO:0031648//protein destabilization;GO:0032147//activation of protein kinase activity;GO:0032689//negative regulation of interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032880//regulation of protein localization;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0046007//negative regulation of activated T cell proliferation;GO:0046686//response to cadmium ion;GO:0046688//response to copper ion;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051260//protein homooligomerization;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071280//cellular response to copper ion;GO:0071466//cellular response to xenobiotic stimulus;GO:0090314//positive regulation of protein targeting to membrane;GO:0090647//modulation of age-related behavioral decline;GO:0097062//dendritic spine maintenance;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1900449//regulation of glutamate receptor signaling pathway;GO:1901216//positive regulation of neuron death;GO:1901379//regulation of potassium ion transmembrane transport;GO:1902430//negative regulation of amyloid-beta formation;GO:1902938//regulation of intracellular calcium activated chloride channel activity;GO:1902951//negative regulation of dendritic spine maintenance;GO:1902992//negative regulation of amyloid precursor protein catabolic process;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1904645//response to amyloid-beta;GO:1904646//cellular response to amyloid-beta;GO:1905664//regulation of calcium ion import across plasma membrane;GO:1990535//neuron projection maintenance	--
ENSG00000171872	0	0	0	0	0	0	0	0	0	0	0	0	KLF17	Kruppel like factor 17 [Source:HGNC Symbol;Acc:HGNC:18830]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000171873	0.229	0.114	0.288	0.133	0.097	0.383	14	7	13	6	5	17	ADRA1D	adrenoceptor alpha 1D [Source:HGNC Symbol;Acc:HGNC:280]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Circulatory system;Circulatory system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04270//Vascular smooth muscle contraction;ko04970//Salivary secretion	K04137;K04137;K04137;K04137;K04137;K04137	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004937//alpha1-adrenergic receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0045907//positive regulation of vasoconstriction;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0150099//neuron-glial cell signaling	--
ENSG00000171877	28.858	26.641	22.247	13.093	16.374	17.283	2793	2486	1572	899	1261	1199	FRMD5	FERM domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28214]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding	GO:0030334//regulation of cell migration;GO:0031032//actomyosin structure organization;GO:0045785//positive regulation of cell adhesion;GO:2000146//negative regulation of cell motility	--
ENSG00000171885	0.065	0	0	0	0	0.125	7	0	0	0	0	3	AQP4	aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637]	Organismal Systems;Organismal Systems	Digestive system;Excretory system	ko04976//Bile secretion;ko04962//Vasopressin-regulated water reabsorption	K09866;K09866	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009925//basal plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030315//T-tubule;GO:0031253//cell projection membrane;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0097450//astrocyte end-foot	GO:0005515//protein binding;GO:0015250//water channel activity;GO:0015267//channel activity;GO:0042802//identical protein binding	GO:0003091//renal water homeostasis;GO:0006833//water transport;GO:0007565//female pregnancy;GO:0009314//response to radiation;GO:0009992//cellular water homeostasis;GO:0010574//regulation of vascular endothelial growth factor production;GO:0015670//carbon dioxide transport;GO:0030104//water homeostasis;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0042538//hyperosmotic salinity response;GO:0050891//multicellular organismal water homeostasis;GO:0051289//protein homotetramerization;GO:0051384//response to glucocorticoid;GO:0055085//transmembrane transport;GO:0060354//negative regulation of cell adhesion molecule production;GO:0071333//cellular response to glucose stimulus;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0071392//cellular response to estradiol stimulus;GO:0090660//cerebrospinal fluid circulation;GO:0098609//cell-cell adhesion	--
ENSG00000171903	0.081	0.258	0.153	0.077	0.098	0.046	5	16	7	3	5	2	CYP4F11	cytochrome P450 family 4 subfamily F member 11 [Source:HGNC Symbol;Acc:HGNC:13265]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005504//fatty acid binding;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0070330//aromatase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0007596//blood coagulation;GO:0019369//arachidonic acid metabolic process;GO:0031408//oxylipin biosynthetic process;GO:0036101//leukotriene B4 catabolic process;GO:0042361//menaquinone catabolic process;GO:0042376//phylloquinone catabolic process;GO:0042377//vitamin K catabolic process;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000171914	12.603	12.429	12.565	11.249	12.391	8.948	2164	2131	1615	1465	1835	1143	TLN2	talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]	Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Cellular community - eukaryotes;Immune system	ko05131//Shigellosis;ko05166//Human T-cell leukemia virus 1 infection;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04611//Platelet activation	K06271;K06271;K06271;K06271;K06271	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0098609//cell-cell adhesion	--
ENSG00000171916	0	0	0.059	0.059	0.155	0	0	0	1	1	3	0	LGALS9C	galectin 9C [Source:HGNC Symbol;Acc:HGNC:33874]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	"GO:0010628//positive regulation of gene expression;GO:0032689//negative regulation of interferon-gamma production;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000171928	26.865	25.717	24.938	25.131	24.963	27.995	969.82	945.72	667.23	678.09	743.56	710.51	TVP23B	trans-golgi network vesicle protein 23 homolog B [Source:HGNC Symbol;Acc:HGNC:20399]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding	GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport	--
ENSG00000171931	0.018	0.014	0.081	0	0	0	1.24	1	4	0	0	0	FBXW10	F-box and WD repeat domain containing 10 [Source:HGNC Symbol;Acc:HGNC:1211]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000171936	0	0	0	0	0	0	0	0	0	0	0	0	OR10H3	olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000171940	12.133	11.404	12.957	10.214	10.379	14.386	1337	1336	1059	815	1005	1080	ZNF217	zinc finger protein 217 [Source:HGNC Symbol;Acc:HGNC:13009]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0016607//nuclear speck	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000171942	0	0	0	0	0	0	0	0	0	0	0	0	OR10H2	olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000171943	2.15	2.506	2.309	1.376	1.902	2.228	184.65	210.97	120.05	84.26	121.82	125.81	SRGAP2C	SLIT-ROBO Rho GTPase activating protein 2C [Source:HGNC Symbol;Acc:HGNC:30584]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07526	GO:0005737//cytoplasm	GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0007399//nervous system development;GO:0021816//extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration;GO:0021987//cerebral cortex development;GO:0030336//negative regulation of cell migration;GO:0051490//negative regulation of filopodium assembly;GO:0061000//negative regulation of dendritic spine development;GO:1904861//excitatory synapse assembly;GO:1904862//inhibitory synapse assembly;GO:2001224//positive regulation of neuron migration	--
ENSG00000171944	0	0	0	0	0	0	0	0	0	0	0	0	OR52A5	olfactory receptor family 52 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:19580]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000171951	0.713	0.65	0.59	0.792	0.445	0.218	36	33	22	17	19	8	SCG2	secretogranin II [Source:HGNC Symbol;Acc:HGNC:10575]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0030141//secretory granule;GO:0031045//dense core granule;GO:0098992//neuronal dense core vesicle	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042056//chemoattractant activity	GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006954//inflammatory response;GO:0009306//protein secretion;GO:0035556//intracellular signal transduction;GO:0043542//endothelial cell migration;GO:0048245//eosinophil chemotaxis;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000171953	15.64	17.625	17.185	18.616	16.264	16.487	382	461	336	346	397	323	ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:18802]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0005515//protein binding	GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0043461//proton-transporting ATP synthase complex assembly	--
ENSG00000171954	0	0	0	0	0.023	0	0	0	0	0	1	0	CYP4F22	cytochrome P450 family 4 subfamily F member 22 [Source:HGNC Symbol;Acc:HGNC:26820]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006690//icosanoid metabolic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000171956	0	0	0	0	0	0	0	0	0	0	0	0	FOXB1	forkhead box B1 [Source:HGNC Symbol;Acc:HGNC:3799]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001655//urogenital system development;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007412//axon target recognition;GO:0007595//lactation;GO:0008542//visual learning;GO:0009653//anatomical structure morphogenesis;GO:0021510//spinal cord development;GO:0021767//mammillary body development;GO:0021794//thalamus development;GO:0021855//hypothalamus cell migration;GO:0022029//telencephalon cell migration;GO:0030154//cell differentiation;GO:0030901//midbrain development;GO:0033504//floor plate development;GO:0043524//negative regulation of neuron apoptotic process;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0061374//mammillothalamic axonal tract development;GO:0061377//mammary gland lobule development;GO:0061379//inferior colliculus development;GO:0061381//cell migration in diencephalon"	Fork_head
ENSG00000171960	9.719	10.559	10.008	7.989	8.218	9.099	188	200	138	120	135	122	PPIH	peptidylprolyl isomerase H [Source:HGNC Symbol;Acc:HGNC:14651]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K09567	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071001//U4/U6 snRNP	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0043021//ribonucleoprotein complex binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006397//mRNA processing;GO:0006457//protein folding;GO:0008380//RNA splicing;GO:0045070//positive regulation of viral genome replication;GO:0065003//protein-containing complex assembly"	--
ENSG00000171962	3.536	3.722	3.258	3.57	2.547	2.698	142	135	100	78	74	52	DRC3	dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000171970	1.408	1.875	1.194	1.748	1.304	1.319	56	77	35	47	45	37	ZNF57	zinc finger protein 57 [Source:HGNC Symbol;Acc:HGNC:13125]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000171984	2.332	1.924	3.823	3.308	3.619	4.053	79	61	85	83	88	82	SHLD1	shieldin complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:26318]	-	-	-	-	GO:0000785//chromatin;GO:0005694//chromosome;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0002208//somatic diversification of immunoglobulins involved in immune response;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0043247//telomere maintenance in response to DNA damage;GO:0045830//positive regulation of isotype switching;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2001032//regulation of double-strand break repair via nonhomologous end joining;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000171988	5.382	3.189	3.009	1.681	2.751	2.835	917	553	335	200	387	325	JMJD1C	jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K11449	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0046966//thyroid hormone receptor binding;GO:0051213//dioxygenase activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007596//blood coagulation;GO:0033169//histone H3-K9 demethylation"	--
ENSG00000171989	0.028	0.027	0	0	0	0	1	1	0	0	0	0	LDHAL6B	lactate dehydrogenase A like 6B [Source:HGNC Symbol;Acc:HGNC:21481]	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:1990204//oxidoreductase complex	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0006089//lactate metabolic process;GO:0006090//pyruvate metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process	--
ENSG00000171992	27.238	30.921	20.546	14.371	15.917	11.714	3040	3517	1680	1172	1498	948	SYNPO	synaptopodin [Source:HGNC Symbol;Acc:HGNC:30672]	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K21112	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0045202//synapse;GO:0097444//spine apparatus	GO:0003779//actin binding;GO:0005515//protein binding	GO:0032233//positive regulation of actin filament bundle assembly;GO:0051492//regulation of stress fiber assembly;GO:0098886//modification of dendritic spine;GO:1905355//spine apparatus assembly	--
ENSG00000172000	0.117	0.058	0	0	0	0	2	2	0	0	0	0	ZNF556	zinc finger protein 556 [Source:HGNC Symbol;Acc:HGNC:25669]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000172005	2.446	3.54	3.131	3.122	3.843	2.628	55	80	52	52	73	43	MAL	"mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0120003//hinge region between urothelial plaques of apical plasma membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0019911//structural constituent of myelin sheath	GO:0001766//membrane raft polarization;GO:0002175//protein localization to paranode region of axon;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0042552//myelination;GO:0045176//apical protein localization;GO:0098737//protein insertion into plasma membrane;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000172006	3.766	3.507	3.031	3.335	3.064	4.162	230	214	135	145	166	181	ZNF554	zinc finger protein 554 [Source:HGNC Symbol;Acc:HGNC:26629]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000172007	2.478	2.018	1.671	1.124	1.46	1.643	199	166	100	69	100	97	RAB33B	"RAB33B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16075]"	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K07920	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0016020//membrane;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000045//autophagosome assembly;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0015031//protein transport;GO:0032482//Rab protein signal transduction;GO:0034067//protein localization to Golgi apparatus;GO:0048705//skeletal system morphogenesis;GO:1903358//regulation of Golgi organization;GO:1903434//negative regulation of constitutive secretory pathway;GO:2000156//regulation of retrograde vesicle-mediated transport, Golgi to ER"	--
ENSG00000172009	51.431	54.664	53.382	78.27	54.67	74.331	2105	2179	1703	2122	1980	2193	THOP1	thimet oligopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:11793]	Human Diseases;Organismal Systems	Infectious disease: parasitic;Endocrine system	ko05143//African trypanosomiasis;ko04614//Renin-angiotensin system	K01392;K01392	GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000209//protein polyubiquitination;GO:0006508//proteolysis;GO:0006518//peptide metabolic process	--
ENSG00000172014	0.117	0.012	0.065	0.031	0	0.016	10.07	1	4.1	2	0	1	ANKRD20A4P	"ankyrin repeat domain 20 family member A4, pseudogene [Source:HGNC Symbol;Acc:HGNC:31982]"	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000172016	0	0	0	0	0	0	0	0	0	0	0	0	REG3A	regenerating family member 3 alpha [Source:HGNC Symbol;Acc:HGNC:8601]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0042834//peptidoglycan binding;GO:0070492//oligosaccharide binding	GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0008284//positive regulation of cell population proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0043434//response to peptide hormone;GO:0044278//cell wall disruption in other organism;GO:0045617//negative regulation of keratinocyte differentiation;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090303//positive regulation of wound healing	--
ENSG00000172020	48.276	46.555	39.306	40.625	48.483	32.667	1503	1457	902	935	1275	740	GAP43	growth associated protein 43 [Source:HGNC Symbol;Acc:HGNC:4140]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031527//filopodium membrane;GO:0032584//growth cone membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0071944//cell periphery;GO:0098982//GABA-ergic synapse	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0035727//lysophosphatidic acid binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0009611//response to wounding;GO:0010001//glial cell differentiation;GO:0016198//axon choice point recognition;GO:0030154//cell differentiation;GO:0031103//axon regeneration;GO:0040008//regulation of growth;GO:0042246//tissue regeneration;GO:0045165//cell fate commitment;GO:0051489//regulation of filopodium assembly;GO:0099150//regulation of postsynaptic specialization assembly	--
ENSG00000172023	0	0	0	0	0	0	0	0	0	0	0	0	REG1B	regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0042834//peptidoglycan binding;GO:0070492//oligosaccharide binding	GO:0008284//positive regulation of cell population proliferation;GO:0043434//response to peptide hormone;GO:0044278//cell wall disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000172031	5.909	6.012	5.5	5.484	3.934	4.153	176	180	121	121	99	90	EPHX4	epoxide hydrolase 4 [Source:HGNC Symbol;Acc:HGNC:23758]	Human Diseases;Human Diseases	Cancer: overview;Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation	K22369;K22369	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	-	--
ENSG00000172037	118.137	114.985	136.229	152.671	159.664	187.912	13944	13643	11876	13349	15923	16139	LAMB2	laminin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6487]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06243;K06243;K06243;K06243;K06243;K06243;K06243;K06243	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005608//laminin-3 complex;GO:0005788//endoplasmic reticulum lumen;GO:0031594//neuromuscular junction;GO:0043083//synaptic cleft;GO:0043256//laminin complex;GO:0043260//laminin-11 complex;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005178//integrin binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0000904//cell morphogenesis involved in differentiation;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007528//neuromuscular junction development;GO:0007601//visual perception;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0014002//astrocyte development;GO:0014044//Schwann cell development;GO:0016477//cell migration;GO:0031175//neuron projection development;GO:0034446//substrate adhesion-dependent cell spreading;GO:0045785//positive regulation of cell adhesion;GO:0048677//axon extension involved in regeneration;GO:0050808//synapse organization;GO:0051149//positive regulation of muscle cell differentiation;GO:0060041//retina development in camera-type eye;GO:0070831//basement membrane assembly;GO:0072249//metanephric glomerular visceral epithelial cell development;GO:0072274//metanephric glomerular basement membrane development;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway	--
ENSG00000172046	18.125	20.416	21.268	20.442	21.833	22.024	1746	1993	1516	1462	1785	1540	USP19	ubiquitin specific peptidase 19 [Source:HGNC Symbol;Acc:HGNC:12617]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031647//regulation of protein stability;GO:0034976//response to endoplasmic reticulum stress;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0050821//protein stabilization;GO:0071108//protein K48-linked deubiquitination;GO:0090068//positive regulation of cell cycle process;GO:1900037//regulation of cellular response to hypoxia;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:1904292//regulation of ERAD pathway	--
ENSG00000172053	129.079	131.808	139.68	153.19	137.906	129.098	4549	4539	3396	3854	4174	3415	QARS1	glutaminyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:9751]	Metabolism;Genetic Information Processing	Global and overview maps;Translation	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis	K01886;K01886	GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0032991//protein-containing complex;GO:0110165//cellular anatomical entity	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004819//glutamine-tRNA ligase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0019901//protein kinase binding	"GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006425//glutaminyl-tRNA aminoacylation;GO:0006469//negative regulation of protein kinase activity;GO:0007420//brain development;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0043039//tRNA aminoacylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000172057	24.809	22.956	24.891	23.433	26.523	22.45	1041	1009	804	759	917	708	ORMDL3	ORMDL sphingolipid biosynthesis regulator 3 [Source:HGNC Symbol;Acc:HGNC:16038]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0035339//SPOTS complex;GO:0035579//specific granule membrane	GO:0005515//protein binding	GO:0002903//negative regulation of B cell apoptotic process;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0006940//regulation of smooth muscle contraction;GO:0010508//positive regulation of autophagy;GO:0042552//myelination;GO:0061744//motor behavior;GO:0090153//regulation of sphingolipid biosynthetic process;GO:0090156//cellular sphingolipid homeostasis;GO:1900060//negative regulation of ceramide biosynthetic process;GO:1900182//positive regulation of protein localization to nucleus;GO:1904221//negative regulation of serine C-palmitoyltransferase activity;GO:2000303//regulation of ceramide biosynthetic process	--
ENSG00000172058	21.939	20.665	21.551	20.88	19.773	5.83	344.1	326.14	246.96	232.48	266.16	79.85	SERF1A	small EDRK-rich factor 1A [Source:HGNC Symbol;Acc:HGNC:10755]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0031648//protein destabilization;GO:1990000//amyloid fibril formation	--
ENSG00000172059	6.671	6.846	6.414	5.347	5.057	5.061	555	571	390	310	347	293	KLF11	Kruppel like factor 11 [Source:HGNC Symbol;Acc:HGNC:11811]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:1901653//cellular response to peptide"	zf-C2H2
ENSG00000172061	0.197	0.407	0.252	0.122	0.116	0.083	24	34	20	11	12	5	LRRC15	leucine rich repeat containing 15 [Source:HGNC Symbol;Acc:HGNC:20818]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0043236//laminin binding	GO:0030335//positive regulation of cell migration;GO:0046813//receptor-mediated virion attachment to host cell;GO:1903077//negative regulation of protein localization to plasma membrane	--
ENSG00000172062	7.768	6.832	7.949	7.59	7.358	8.772	229.18	203.3	157.74	167.31	181.85	188.46	SMN1	"survival of motor neuron 1, telomeric [Source:HGNC Symbol;Acc:HGNC:11117]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0030018//Z disc;GO:0030424//axon;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0097504//Gemini of coiled bodies	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0006353//DNA-templated transcription, termination;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing"	--
ENSG00000172071	5.013	5.313	5.925	3.959	4.252	4.618	414	448	357	248	327	264	EIF2AK3	eukaryotic translation initiation factor 2 alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:3255]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes	"Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Folding, sorting and degradation;Endocrine and metabolic disease;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cell growth and death;Transport and catabolism"	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05020//Prion disease;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko05162//Measles;ko04210//Apoptosis;ko04137//Mitophagy - animal	K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860;K08860	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0051879//Hsp90 protein binding;GO:0106310//protein serine kinase activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001525//angiogenesis;GO:0002063//chondrocyte development;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006983//ER overload response;GO:0006986//response to unfolded protein;GO:0007029//endoplasmic reticulum organization;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0016310//phosphorylation;GO:0017148//negative regulation of translation;GO:0018105//peptidyl-serine phosphorylation;GO:0019722//calcium-mediated signaling;GO:0030282//bone mineralization;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031018//endocrine pancreas development;GO:0031642//negative regulation of myelination;GO:0032055//negative regulation of translation in response to stress;GO:0032057//negative regulation of translational initiation in response to stress;GO:0034198//cellular response to amino acid starvation;GO:0034976//response to endoplasmic reticulum stress;GO:0036492//eiF2alpha phosphorylation in response to endoplasmic reticulum stress;GO:0036499//PERK-mediated unfolded protein response;GO:0042149//cellular response to glucose starvation;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0046777//protein autophosphorylation;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0060734//regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:0070417//cellular response to cold;GO:1900182//positive regulation of protein localization to nucleus;GO:1902235//regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1990737//response to manganese-induced endoplasmic reticulum stress	--
ENSG00000172073	0	0	0	0	0	0	0	0	0	0	0	0	TEX37	testis expressed 37 [Source:HGNC Symbol;Acc:HGNC:26341]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000172081	12.561	12.493	13.568	14.922	13.093	11.442	840	875	704	661	762	524	MOB3A	MOB kinase activator 3A [Source:HGNC Symbol;Acc:HGNC:29802]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity	--
ENSG00000172086	14.061	14.228	12.752	10.373	10.39	10.817	527	536	353	288	329	295	KRCC1	lysine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28039]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000172113	9.016	9.004	9.444	8.653	10.798	9.968	504	531.35	408	337	431	443	NME6	NME/NM23 nucleoside diphosphate kinase 6 [Source:HGNC Symbol;Acc:HGNC:20567]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006915//apoptotic process;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation;GO:0030308//negative regulation of cell growth;GO:0045839//negative regulation of mitotic nuclear division;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000172115	58.753	55.314	65.008	70.262	60.773	72.051	2335	2313	1911	1946	2064	2048	CYCS	"cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC:19986]"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Global and overview maps;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Energy metabolism;Cell growth and death;Cardiovascular disease;Infectious disease: parasitic;Cancer: specific types;Cancer: specific types;Drug resistance: antineoplastic;Cell growth and death;Infectious disease: bacterial;Cell growth and death	ko01100//Metabolic pathways;ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05164//Influenza A;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko00190//Oxidative phosphorylation;ko04210//Apoptosis;ko05416//Viral myocarditis;ko05145//Toxoplasmosis;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko01524//Platinum drug resistance;ko04115//p53 signaling pathway;ko05134//Legionellosis;ko04215//Apoptosis - multiple species	K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738;K08738	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0043293//apoptosome;GO:0070469//respirasome	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0020037//heme binding;GO:0046872//metal ion binding	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0006915//apoptotic process;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0022900//electron transport chain;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045333//cellular respiration;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097202//activation of cysteine-type endopeptidase activity"	--
ENSG00000172116	0	0	0	0	0.082	0	0	0	0	0	1	0	CD8B	CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Immune disease;Immune system;Immune system	ko05135//Yersinia infection;ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04660//T cell receptor signaling pathway;ko04612//Antigen processing and presentation	K06459;K06459;K06459;K06459;K06459;K06459	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0042101//T cell receptor complex;GO:0043235//receptor complex	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0042288//MHC class I protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042110//T cell activation;GO:0050776//regulation of immune response;GO:0050852//T cell receptor signaling pathway	--
ENSG00000172123	3.622	4.1	3.35	2.869	3.109	2.72	161	189	107	93	116	97	SLFN12	schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000172137	0	0	0	0.092	0.042	0	0	0	0	1	1	0	CALB2	calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005921//gap junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098793//presynapse	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0099534//calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration	GO:0051480//regulation of cytosolic calcium ion concentration;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1900271//regulation of long-term synaptic potentiation	--
ENSG00000172139	0	0	0.016	0	0.014	0	0	0	1	0	1	0	SLC9C1	solute carrier family 9 member C1 [Source:HGNC Symbol;Acc:HGNC:31401]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005216//ion channel activity;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000172146	0	0	0	0	0	0	0	0	0	0	0	0	OR1A1	olfactory receptor family 1 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8179]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172150	0	0	0	0	0	0	0	0	0	0	0	0	OR1A2	olfactory receptor family 1 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8180]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0032467//positive regulation of cytokinesis;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172154	0	0	0	0	0	0	0	0	0	0	0	0	OR8I2	olfactory receptor family 8 subfamily I member 2 [Source:HGNC Symbol;Acc:HGNC:15310]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172155	0	0	0	0	0	0	0	0	0	0	0	0	LCE1D	late cornified envelope 1D [Source:HGNC Symbol;Acc:HGNC:29465]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization;GO:0050890//cognition;GO:0071277//cellular response to calcium ion	--
ENSG00000172156	0	0	0	0	0	0	0	0	0	0	0	0	CCL11	C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610]	Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system;Immune disease;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko05310//Asthma;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway	K16597;K16597;K16597;K16597;K16597	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031728//CCR3 chemokine receptor binding;GO:0046983//protein dimerization activity;GO:0048018//receptor ligand activity;GO:0048020//CCR chemokine receptor binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007611//learning or memory;GO:0008360//regulation of cell shape;GO:0009314//response to radiation;GO:0009615//response to virus;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0043547//positive regulation of GTPase activity;GO:0045766//positive regulation of angiogenesis;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050768//negative regulation of neurogenesis;GO:0060326//cell chemotaxis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060763//mammary duct terminal end bud growth;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0090647//modulation of age-related behavioral decline	--
ENSG00000172159	0.603	0.493	0.425	0.398	0.376	0.355	58	52	33	31	18	19	FRMD3	FERM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24125]	-	-	-	-	GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding	GO:0031032//actomyosin structure organization	--
ENSG00000172164	28.856	24.571	25.645	19.391	20.271	22.757	2962	2533	1943	1473	1757	1697	SNTB1	syntrophin beta 1 [Source:HGNC Symbol;Acc:HGNC:11168]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016020//membrane;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0045202//synapse	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0030165//PDZ domain binding	GO:0006936//muscle contraction	--
ENSG00000172167	0.927	0.594	0.511	0.806	0.465	0.744	59	38	24	38	25	34	MTBP	MDM2 binding protein [Source:HGNC Symbol;Acc:HGNC:7417]	-	-	-	-	GO:0000776//kinetochore;GO:0000785//chromatin	-	GO:0007049//cell cycle;GO:0007089//traversing start control point of mitotic cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0031396//regulation of protein ubiquitination;GO:0034501//protein localization to kinetochore;GO:0045839//negative regulation of mitotic nuclear division	--
ENSG00000172171	4.318	4.287	4.189	2.32	2.492	3.59	126	121	86	52	61	79	TEFM	"transcription elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26223]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030337//DNA polymerase processivity factor activity	GO:0006119//oxidative phosphorylation;GO:0006390//mitochondrial transcription;GO:0006392//transcription elongation from mitochondrial promoter;GO:0050790//regulation of catalytic activity	--
ENSG00000172172	10.613	9.624	10.198	8.819	8.855	12.167	278	254	198	171	196	219	MRPL13	mitochondrial ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:14278]	Genetic Information Processing	Translation	ko03010//Ribosome	K02871	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0017148//negative regulation of translation;GO:0032543//mitochondrial translation	--
ENSG00000172175	2.68	2.744	1.687	2.582	2.581	3.344	318	274	126	204	249	254	MALT1	MALT1 paracaspase [Source:HGNC Symbol;Acc:HGNC:6819]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Immune system;Immune system;Immune system	ko05131//Shigellosis;ko05152//Tuberculosis;ko04064//NF-kappa B signaling pathway;ko04662//B cell receptor signaling pathway;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway	K07369;K07369;K07369;K07369;K07369;K07369	GO:0001650//fibrillar center;GO:0002096//polkadots;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0002020//protease binding;GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0019209//kinase activator activity;GO:0042802//identical protein binding;GO:0043621//protein self-association	GO:0001923//B-1 B cell differentiation;GO:0002376//immune system process;GO:0002726//positive regulation of T cell cytokine production;GO:0006508//proteolysis;GO:0006952//defense response;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0009620//response to fungus;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032743//positive regulation of interleukin-2 production;GO:0042098//T cell proliferation;GO:0042113//B cell activation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0050852//T cell receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051168//nuclear export;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:2000321//positive regulation of T-helper 17 cell differentiation	--
ENSG00000172179	0	0	0	0	0	0	0	0	0	0	0	0	PRL	prolactin [Source:HGNC Symbol;Acc:HGNC:9445]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K05439;K05439;K05439;K05439;K05439	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031904//endosome lumen;GO:0031982//vesicle	GO:0005148//prolactin receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0001937//negative regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0016525//negative regulation of angiogenesis;GO:0030879//mammary gland development;GO:0031667//response to nutrient levels;GO:0040014//regulation of multicellular organism growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903489//positive regulation of lactation	--
ENSG00000172183	0.262	0.214	0.082	0.547	0.214	0.166	5	8	1	8	3	2	ISG20	interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016605//PML body	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008859//exoribonuclease II activity;GO:0016787//hydrolase activity;GO:0030619//U1 snRNA binding;GO:0030620//U2 snRNA binding;GO:0034511//U3 snoRNA binding;GO:0046872//metal ion binding	"GO:0000738//DNA catabolic process, exonucleolytic;GO:0002376//immune system process;GO:0006364//rRNA processing;GO:0006401//RNA catabolic process;GO:0009615//response to virus;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000172188	0	0	0	0	0	0	0	0	0	0	0	0	OR4C11	olfactory receptor family 4 subfamily C member 11 [Source:HGNC Symbol;Acc:HGNC:15167]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172197	0.146	0.078	0.106	0.075	0.146	0.077	13.09	7.02	7.01	5.01	11.08	5.05	MBOAT1	membrane bound O-acyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21579]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13517;K13517;K13517	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0106262//1-acylglycerophosphoethanolamine O-acyltransferase activity;GO:0106263//1-acylglycerophosphoserine O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0010975//regulation of neuron projection development;GO:0030258//lipid modification;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling	--
ENSG00000172199	0	0	0	0	0	0	0	0	0	0	0	0	OR8U1	olfactory receptor family 8 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:19611]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172201	8.589	6.997	6.877	9.663	9.813	11.189	690	565	408	575	666	654	ID4	"inhibitor of DNA binding 4, HLH protein [Source:HGNC Symbol;Acc:HGNC:5363]"	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K17695;K17695	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0007405//neuroblast proliferation;GO:0007420//brain development;GO:0007623//circadian rhythm;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0021766//hippocampus development;GO:0021895//cerebral cortex neuron differentiation;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0032922//circadian regulation of gene expression;GO:0034613//cellular protein localization;GO:0045444//fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048712//negative regulation of astrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0060512//prostate gland morphogenesis;GO:0060740//prostate gland epithelium morphogenesis;GO:0060741//prostate gland stromal morphogenesis;GO:0061682//seminal vesicle morphogenesis"	bHLH
ENSG00000172208	0	0	0	0	0	0	0	0	0	0	0	0	OR4X2	olfactory receptor family 4 subfamily X member 2 [Source:HGNC Symbol;Acc:HGNC:15184]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172209	0	0	0	0	0	0	0	0	0	0	0	0	GPR22	G protein-coupled receptor 22 [Source:HGNC Symbol;Acc:HGNC:4477]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0030030//cell projection organization	--
ENSG00000172215	0.081	0.017	0.023	0.023	0.112	0.073	2	1	1	1	5	3	CXCR6	C-X-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:16647]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway	K04191;K04191	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019079//viral genome replication;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000172216	46.324	40.427	47.281	48.487	49.835	56.604	1767	1550	1332	1370	1606	1571	CEBPB	CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834]	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Signal transduction;Immune system	ko05202//Transcriptional misregulation in cancer;ko05152//Tuberculosis;ko04668//TNF signaling pathway;ko04657//IL-17 signaling pathway	K10048;K10048;K10048;K10048	"GO:0000779//condensed chromosome, centromeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0036488//CHOP-C/EBP complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990647//C/EBP complex"	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031490//chromatin DNA binding;GO:0035035//histone acetyltransferase binding;GO:0035259//glucocorticoid receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001541//ovarian follicle development;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007613//memory;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0032496//response to lipopolysaccharide;GO:0032675//regulation of interleukin-6 production;GO:0032753//positive regulation of interleukin-4 production;GO:0033598//mammary gland epithelial cell proliferation;GO:0034976//response to endoplasmic reticulum stress;GO:0042130//negative regulation of T cell proliferation;GO:0042742//defense response to bacterium;GO:0043524//negative regulation of neuron apoptotic process;GO:0045444//fat cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050729//positive regulation of inflammatory response;GO:0050873//brown fat cell differentiation;GO:0060644//mammary gland epithelial cell differentiation;GO:0061515//myeloid cell development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070169//positive regulation of biomineral tissue development;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071347//cellular response to interleukin-1;GO:0071407//cellular response to organic cyclic compound;GO:0072574//hepatocyte proliferation;GO:0097421//liver regeneration;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0140467//integrated stress response signaling;GO:1901329//regulation of odontoblast differentiation;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:2000120//positive regulation of sodium-dependent phosphate transport;GO:2001198//regulation of dendritic cell differentiation"	TF_bZIP
ENSG00000172232	0	0	0	0.228	0.1	0.146	0	0	0	6	3	2	AZU1	azurocidin 1 [Source:HGNC Symbol;Acc:HGNC:913]	Organismal Systems	Immune system	ko04613//Neutrophil extracellular trap formation	K24665	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0035577//azurophil granule membrane;GO:0035578//azurophil granule lumen;GO:0042582//azurophil granule;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0015643//toxic substance binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0001774//microglial cell activation;GO:0006508//proteolysis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0008347//glial cell migration;GO:0010628//positive regulation of gene expression;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0019730//antimicrobial humoral response;GO:0032724//positive regulation of fractalkine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0042117//monocyte activation;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:0043114//regulation of vascular permeability;GO:0045123//cellular extravasation;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045785//positive regulation of cell adhesion;GO:0045860//positive regulation of protein kinase activity;GO:0048246//macrophage chemotaxis;GO:0050766//positive regulation of phagocytosis;GO:0050829//defense response to Gram-negative bacterium;GO:0050930//induction of positive chemotaxis;GO:0051607//defense response to virus;GO:0060326//cell chemotaxis;GO:0070528//protein kinase C signaling;GO:0070944//neutrophil-mediated killing of bacterium	--
ENSG00000172236	0	0	0	0	0	0	0	0	0	0	0	0	TPSAB1	tryptase alpha/beta 1 [Source:HGNC Symbol;Acc:HGNC:12019]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K01340	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0006952//defense response;GO:0022617//extracellular matrix disassembly	--
ENSG00000172238	0	0	0	0	0	0	0	0	0	0	0	0	ATOH1	atonal bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:797]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001764//neuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0014014//negative regulation of gliogenesis;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0042472//inner ear morphogenesis;GO:0042491//inner ear auditory receptor cell differentiation;GO:0042667//auditory receptor cell fate specification;GO:0042668//auditory receptor cell fate determination;GO:0043066//negative regulation of apoptotic process;GO:0045609//positive regulation of inner ear auditory receptor cell differentiation;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:2000982//positive regulation of inner ear receptor cell differentiation"	bHLH
ENSG00000172239	54.38	47.245	51.735	42.536	42.369	45.819	1982	1644	1318	1075	1236	1205	PAIP1	poly(A) binding protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16945]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0106002//mCRD-mediated mRNA stability complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008494//translation activator activity	"GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0048255//mRNA stabilization;GO:0070934//CRD-mediated mRNA stabilization;GO:1900152//negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000172243	0.079	0.042	0	0.13	0.049	0.244	4	1	0	2	1	5	CLEC7A	C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558]	Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems	Immune system;Infectious disease: bacterial;Transport and catabolism;Immune system	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko04625//C-type lectin receptor signaling pathway	K10074;K10074;K10074;K10074	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001872//(1->3)-beta-D-glucan binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038187//pattern recognition receptor activity;GO:0042287//MHC protein binding;GO:0046872//metal ion binding	"GO:0001775//cell activation;GO:0001878//response to yeast;GO:0001879//detection of yeast;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002366//leukocyte activation involved in immune response;GO:0002376//immune system process;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0006910//phagocytosis, recognition;GO:0006954//inflammatory response;GO:0008037//cell recognition;GO:0008284//positive regulation of cell population proliferation;GO:0009756//carbohydrate mediated signaling;GO:0010628//positive regulation of gene expression;GO:0016046//detection of fungus;GO:0030335//positive regulation of cell migration;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032491//detection of molecule of fungal origin;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0032930//positive regulation of superoxide anion generation;GO:0042110//T cell activation;GO:0042832//defense response to protozoan;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766//positive regulation of phagocytosis;GO:0050850//positive regulation of calcium-mediated signaling;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051251//positive regulation of lymphocyte activation;GO:0051712//positive regulation of killing of cells of other organism;GO:0060267//positive regulation of respiratory burst;GO:0061760//antifungal innate immune response;GO:0070884//regulation of calcineurin-NFAT signaling cascade;GO:0071226//cellular response to molecule of fungal origin;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0090303//positive regulation of wound healing;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1903431//positive regulation of cell maturation;GO:2000318//positive regulation of T-helper 17 type immune response"	--
ENSG00000172244	0.578	0.422	0.365	0.234	0.359	0.318	30	22	14	9	15	12	C5orf34	chromosome 5 open reading frame 34 [Source:HGNC Symbol;Acc:HGNC:24738]	-	-	-	-	-	-	-	--
ENSG00000172247	0.478	0.679	0.231	0.138	0.121	0.047	14	20	5	3	3	1	C1QTNF4	C1q and TNF related 4 [Source:HGNC Symbol;Acc:HGNC:14346]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0070105//positive regulation of interleukin-6-mediated signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000172260	0.556	0.423	0.493	0.365	0.317	0.464	70	53	44	37	31	40	NEGR1	neuronal growth regulator 1 [Source:HGNC Symbol;Acc:HGNC:17302]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06775	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0031225//anchored component of membrane;GO:0043025//neuronal cell body	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007420//brain development;GO:0007626//locomotory behavior;GO:0007631//feeding behavior;GO:0010976//positive regulation of neuron projection development;GO:0051963//regulation of synapse assembly;GO:0098609//cell-cell adhesion	--
ENSG00000172262	9.663	6.569	5.111	7.335	5.748	7.101	412	323	199	215	234	209	ZNF131	zinc finger protein 131 [Source:HGNC Symbol;Acc:HGNC:12915]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	ZBTB
ENSG00000172264	0.628	0.678	0.592	0.574	0.705	0.458	64	69	43	43	36	34	MACROD2	mono-ADP ribosylhydrolase 2 [Source:HGNC Symbol;Acc:HGNC:16126]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019213//deacetylase activity;GO:0140293//ADP-ribosylglutamate hydrolase activity"	GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0009617//response to bacterium;GO:0042278//purine nucleoside metabolic process;GO:0051725//protein de-ADP-ribosylation;GO:0140291//peptidyl-glutamate ADP-deribosylation	--
ENSG00000172269	25.26	24.602	25.217	28.791	29.085	31.507	999.59	987.36	735.48	848.92	968	901	DPAGT1	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:2995]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K01001;K01001	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003975//UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity;GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity;GO:0005515//protein binding;GO:0008963//phospho-N-acetylmuramoyl-pentapeptide-transferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0019348//dolichol metabolic process	--
ENSG00000172270	1197.21	1271.73	1430.356	1759.239	1615.392	1501.737	39773	42503	35132	43350	45416	36334	BSG	basigin (Ok blood group) [Source:HGNC Symbol;Acc:HGNC:1116]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0002080//acrosomal membrane;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030424//axon;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0045296//cadherin binding;GO:0098632//cell-cell adhesion mediator activity	GO:0001525//angiogenesis;GO:0003407//neural retina development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007166//cell surface receptor signaling pathway;GO:0007411//axon guidance;GO:0007566//embryo implantation;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010595//positive regulation of endothelial cell migration;GO:0030593//neutrophil chemotaxis;GO:0032755//positive regulation of interleukin-6 production;GO:0042475//odontogenesis of dentin-containing tooth;GO:0043434//response to peptide hormone;GO:0045494//photoreceptor cell maintenance;GO:0046598//positive regulation of viral entry into host cell;GO:0046689//response to mercury ion;GO:0046697//decidualization;GO:0046718//viral entry into host cell;GO:0051591//response to cAMP;GO:0061154//endothelial tube morphogenesis;GO:0070593//dendrite self-avoidance;GO:0072659//protein localization to plasma membrane;GO:1904466//positive regulation of matrix metallopeptidase secretion	--
ENSG00000172273	3.981	5.102	4.501	5.631	5.448	6.151	263	299	200	251	246	243	HINFP	histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015030//Cajal body	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0046872//metal ion binding"	"GO:0000077//DNA damage checkpoint signaling;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0045184//establishment of protein localization;GO:0045445//myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	zf-C2H2
ENSG00000172288	0	0	0	0	0	0	0	0	0	0	0	0	CDY1	chromodomain Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:1809]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004402//histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0035064//methylated histone binding	"GO:0007283//spermatogenesis;GO:0016573//histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000172289	0	0	0	0	0	0	0	0	0	0	0	0	OR10V1	olfactory receptor family 10 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:15136]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172292	21.693	18.544	17.002	14.428	16.444	16.795	3063	2632	1773	1509	1961	1725	CERS6	ceramide synthase 6 [Source:HGNC Symbol;Acc:HGNC:23826]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K23727;K23727;K23727	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006954//inflammatory response;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process	--
ENSG00000172296	0.921	1.034	0.691	1.039	0.629	1.131	55	54	38	47	39	34	SPTLC3	serine palmitoyltransferase long chain base subunit 3 [Source:HGNC Symbol;Acc:HGNC:16253]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K00654;K00654;K00654	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex	GO:0003824//catalytic activity;GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0030170//pyridoxal phosphate binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0009058//biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0046520//sphingoid biosynthetic process	--
ENSG00000172301	42.475	43.814	43.409	48.83	38.357	41.268	768	798	580	656	587	546	COPRS	coordinator of PRMT5 and differentiation stimulator [Source:HGNC Symbol;Acc:HGNC:28848]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0042393//histone binding	GO:0006325//chromatin organization;GO:0007517//muscle organ development;GO:0043985//histone H4-R3 methylation	--
ENSG00000172315	9.887	10.233	13.452	11.165	10.445	11.293	627	654	608	537	565	532	TP53RK	TP53 regulating kinase [Source:HGNC Symbol;Acc:HGNC:16197]	-	-	-	-	GO:0000408//EKC/KEOPS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0008033//tRNA processing;GO:0016310//phosphorylation;GO:0070525//tRNA threonylcarbamoyladenosine metabolic process;GO:1901796//regulation of signal transduction by p53 class mediator	--
ENSG00000172318	0.288	0.394	0.212	0.378	0.39	0.328	35	48	19	34	40	29	B3GALT1	"beta-1,3-galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:916]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07819;K07819	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047275//glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006682//galactosylceramide biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0030259//lipid glycosylation	--
ENSG00000172320	0	0	0	0	0	0	0	0	0	0	0	0	OR5A1	olfactory receptor family 5 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8319]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172322	0	0	0	0	0	0	0	0	0	0	0	0	CLEC12A	C-type lectin domain family 12 member A [Source:HGNC Symbol;Acc:HGNC:31713]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0030545//signaling receptor regulator activity	-	--
ENSG00000172324	0	0	0	0	0	0	0	0	0	0	0	0	OR5A2	olfactory receptor family 5 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:15249]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172331	8.488	8.41	8.279	6.124	6.68	8.365	302	300	217	161	201	216	BPGM	bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00010//Glycolysis / Gluconeogenesis;ko00260//Glycine, serine and threonine metabolism"	K01837;K01837;K01837	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases"	GO:0005975//carbohydrate metabolic process;GO:0006096//glycolytic process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0048821//erythrocyte development;GO:1901136//carbohydrate derivative catabolic process	--
ENSG00000172336	14.123	12.979	15.129	15.391	13.696	13.876	249	230	197	201	204	178	POP7	"POP7 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:19949]"	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14527	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0030681//multimeric ribonuclease P complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000172339	0.71	0.767	0.78	0.625	0.67	0.558	138	150	112	90	110	79	ALG14	ALG14 UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:28287]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K07441;K07441;K07441	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043541//UDP-N-acetylglucosamine transferase complex	-	GO:0006488//dolichol-linked oligosaccharide biosynthetic process	--
ENSG00000172340	15.038	15.407	13.861	15.772	12.963	12.886	733	752	499	558	527	457	SUCLG2	succinate-CoA ligase GDP-forming subunit beta [Source:HGNC Symbol;Acc:HGNC:11450]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00640//Propanoate metabolism;ko00020//Citrate cycle (TCA cycle)	K01900;K01900;K01900;K01900	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0042709//succinate-CoA ligase complex;GO:0045244//succinate-CoA ligase complex (GDP-forming)	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0004776//succinate-CoA ligase (GDP-forming) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006099//tricarboxylic acid cycle;GO:0006104//succinyl-CoA metabolic process;GO:1901289//succinyl-CoA catabolic process	--
ENSG00000172345	0.361	0.94	0.238	0.571	0.54	0.356	15.66	33.15	8.41	30	37.75	10.77	STARD5	StAR related lipid transfer domain containing 5 [Source:HGNC Symbol;Acc:HGNC:18065]	-	-	-	-	GO:0005829//cytosol	GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0032052//bile acid binding;GO:0120020//cholesterol transfer activity	GO:0006869//lipid transport;GO:0070508//cholesterol import;GO:0120009//intermembrane lipid transfer	--
ENSG00000172346	6.422	6.711	3.999	6.586	7.759	8.145	337	354	155	256	344	311	CSDC2	cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0043488//regulation of mRNA stability	CSD
ENSG00000172348	6.933	6.022	4.884	5.081	6.208	4.722	488	425	254	262	365	241	RCAN2	regulator of calcineurin 2 [Source:HGNC Symbol;Acc:HGNC:3041]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K17903	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity	GO:0019722//calcium-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000172349	0.407	0.53	0.69	0.312	0.628	0.697	32.34	52.85	37.59	14	42.25	28.23	IL16	interleukin 16 [Source:HGNC Symbol;Acc:HGNC:5980]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22628	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016607//nuclear speck;GO:0090543//Flemming body	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042609//CD4 receptor binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0030595//leukocyte chemotaxis;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0050729//positive regulation of inflammatory response;GO:0050930//induction of positive chemotaxis;GO:0051924//regulation of calcium ion transport	--
ENSG00000172350	0.124	0.255	0.529	0.154	0.269	0.4	9	17	11	9	18	23	ABCG4	ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05680	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0034041//ABC-type sterol transporter activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0140359//ABC-type transporter activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006869//lipid transport;GO:0010875//positive regulation of cholesterol efflux;GO:0015918//sterol transport;GO:0033344//cholesterol efflux;GO:0042632//cholesterol homeostasis;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0055085//transmembrane transport;GO:0071403//cellular response to high density lipoprotein particle stimulus;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000172352	0	0	0	0	0	0	0	0	0	0	0	0	CDY1B	chromodomain Y-linked 1B [Source:HGNC Symbol;Acc:HGNC:23920]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004402//histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0035064//methylated histone binding	"GO:0007283//spermatogenesis;GO:0016573//histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000172354	95.348	95.956	99.666	97.505	105.765	100.534	2617	2860	2083	2161	2591	2173	GNB2	G protein subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:4398]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537;K04537	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005834//heterotrimeric G-protein complex;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0030159//signaling receptor complex adaptor activity;GO:0044877//protein-containing complex binding;GO:0051020//GTPase binding	GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000172361	1.85	2.84	2.04	1.534	1.439	1.38	70	108	57	43	46	38	CFAP53	cilia and flagella associated protein 53 [Source:HGNC Symbol;Acc:HGNC:26530]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0007368//determination of left/right symmetry;GO:0060271//cilium assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry	--
ENSG00000172362	0.046	0	0	0	0	0	1	0	0	0	0	0	OR5B12	olfactory receptor family 5 subfamily B member 12 [Source:HGNC Symbol;Acc:HGNC:15432]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172365	0	0	0	0	0	0	0	0	0	0	0	0	OR5B2	olfactory receptor family 5 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:8323]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172366	11.853	12.755	16.215	22.538	17.052	20.64	238	254	239	329	286	298	MCRIP2	MAPK regulated corepressor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:14142]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0005515//protein binding	-	--
ENSG00000172367	0	0	0	0	0	0	0	0	0	0	0	0	PDZD3	PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19891]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0043296//apical junction complex;GO:0045177//apical part of cell	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008200//ion channel inhibitor activity;GO:0030251//guanylate cyclase inhibitor activity;GO:0043495//protein-membrane adaptor activity;GO:1990381//ubiquitin-specific protease binding	GO:0006811//ion transport;GO:0006833//water transport;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0009636//response to toxic substance;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0031283//negative regulation of guanylate cyclase activity;GO:0072659//protein localization to plasma membrane	--
ENSG00000172375	3.068	3.985	3.611	3.903	4.373	4.648	248.41	300.64	195.52	226.08	281	245	C2CD2L	C2CD2 like [Source:HGNC Symbol;Acc:HGNC:29000]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032541//cortical endoplasmic reticulum;GO:0098592//cytoplasmic side of apical plasma membrane;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transfer activity;GO:0035091//phosphatidylinositol binding;GO:0043559//insulin binding	GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0120009//intermembrane lipid transfer	--
ENSG00000172377	0	0	0	0	0	0	0	0	0	0	0	0	OR9I1	olfactory receptor family 9 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:14718]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172379	33.426	34.446	35.411	36.72	37.397	40.226	4523	4688	3539	3645	4198	3960	ARNT2	aryl hydrocarbon receptor nuclear translocator 2 [Source:HGNC Symbol;Acc:HGNC:16876]	Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05211//Renal cell carcinoma	K15589;K15589;K15589	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0034751//aryl hydrocarbon receptor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0017162//aryl hydrocarbon receptor binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000172380	49.901	47.277	48.316	45.405	46.6	50.807	4549	4332	3253	3066	3589	3370	GNG12	G protein subunit gamma 12 [Source:HGNC Symbol;Acc:HGNC:19663]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Infectious disease: viral;Cell motility;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347;K04347	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000172382	0.51	0.451	0.805	1.135	0.327	1.436	12	11	14	22	7	26	PRSS27	serine protease 27 [Source:HGNC Symbol;Acc:HGNC:15475]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000172399	0.492	0.64	0.256	0.102	0.09	0.026	26	34	10	4	4	1	MYOZ2	myozenin 2 [Source:HGNC Symbol;Acc:HGNC:1330]	-	-	-	-	GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030017//sarcomere;GO:0030018//Z disc	GO:0003779//actin binding;GO:0005515//protein binding;GO:0030346//protein phosphatase 2B binding;GO:0031433//telethonin binding;GO:0051373//FATZ binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0008150//biological_process;GO:0043503//skeletal muscle fiber adaptation;GO:0045214//sarcomere organization;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade	--
ENSG00000172403	0.648	0.558	0.354	0.152	0.387	0.143	105	90	38	19	51	19	SYNPO2	synaptopodin 2 [Source:HGNC Symbol;Acc:HGNC:17732]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0099023//vesicle tethering complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0031005//filamin binding;GO:0051371//muscle alpha-actinin binding;GO:0051393//alpha-actinin binding;GO:0071889//14-3-3 protein binding	GO:0000045//autophagosome assembly;GO:0030335//positive regulation of cell migration;GO:0032233//positive regulation of actin filament bundle assembly;GO:0061684//chaperone-mediated autophagy;GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity	--
ENSG00000172404	0.056	0	0	0	0.067	0.052	3	0	0	0	3	2	DNAJB7	DnaJ heat shock protein family (Hsp40) member B7 [Source:HGNC Symbol;Acc:HGNC:24986]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0061077//chaperone-mediated protein folding	--
ENSG00000172409	4.747	4.823	5.018	4.731	3.874	5.831	180	162	126	133	124	148	CLP1	cleavage factor polyribonucleotide kinase subunit 1 [Source:HGNC Symbol;Acc:HGNC:16999]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14399	GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005849//mRNA cleavage factor complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046404//polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0051731//polynucleotide 5'-hydroxyl-kinase activity;GO:0051733//polydeoxyribonucleotide kinase activity;GO:0051734//polynucleotide kinase activity;GO:0051736//polyribonucleotide 5'-hydroxyl-kinase activity	"GO:0006378//mRNA polyadenylation;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008033//tRNA processing;GO:0016310//phosphorylation;GO:0021695//cerebellar cortex development;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0031124//mRNA 3'-end processing;GO:0035087//siRNA loading onto RISC involved in RNA interference"	--
ENSG00000172410	0	0	0	0	0	0	0	0	0	0	0	0	INSL5	insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K22001;K22001	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008150//biological_process;GO:2000253//positive regulation of feeding behavior	--
ENSG00000172421	0.249	0.062	0.127	0.084	0.185	0.086	8	2	3	2	5	2	EFCAB3	EF-hand calcium binding domain 3 [Source:HGNC Symbol;Acc:HGNC:26379]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000172425	0.782	0.681	0.53	0.594	0.695	0.941	16	14	8	9	12	14	TTC36	tetratricopeptide repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:33708]	-	-	-	-	-	GO:0005515//protein binding	GO:0006570//tyrosine metabolic process;GO:0007613//memory;GO:0008542//visual learning;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0021954//central nervous system neuron development;GO:0032091//negative regulation of protein binding;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0060271//cilium assembly;GO:1902915//negative regulation of protein polyubiquitination	--
ENSG00000172426	1.639	1.135	1.525	0.654	0.977	1.556	86.77	60.34	59.56	25.65	43.64	59.75	RSPH9	radial spoke head component 9 [Source:HGNC Symbol;Acc:HGNC:21057]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0060091//kinocilium;GO:0097729//9+2 motile cilium	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0044458//motile cilium assembly;GO:0060294//cilium movement involved in cell motility;GO:0062177//radial spoke assembly;GO:1904158//axonemal central apparatus assembly	--
ENSG00000172428	24.336	22.261	25.143	30.207	24.846	24.253	211	194	161	194	182	153	COPS9	COP9 signalosome subunit 9 [Source:HGNC Symbol;Acc:HGNC:21314]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome	GO:0005515//protein binding	GO:0008284//positive regulation of cell population proliferation;GO:0034644//cellular response to UV;GO:0051220//cytoplasmic sequestering of protein;GO:2000435//negative regulation of protein neddylation	--
ENSG00000172432	12.065	10.339	12.287	11.779	10.696	13.117	646	595	496	534	547	573	GTPBP2	GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4670]	-	-	-	-	GO:0005576//extracellular region;GO:0031093//platelet alpha granule lumen	GO:0000166//nucleotide binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding	GO:0006414//translational elongation;GO:0008150//biological_process	--
ENSG00000172456	4.041	3.655	4.698	3.746	3.11	2.844	108	100	97	91	96	56	FGGY	FGGY carbohydrate kinase domain containing [Source:HGNC Symbol;Acc:HGNC:25610]	-	-	-	-	GO:0005575//cellular_component	"GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019150//D-ribulokinase activity"	GO:0005975//carbohydrate metabolic process;GO:0016310//phosphorylation;GO:0019321//pentose metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0070050//neuron cellular homeostasis	--
ENSG00000172457	0	0	0	0	0	0	0	0	0	0	0	0	OR9G4	olfactory receptor family 9 subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:15322]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172458	12.101	11.421	14.796	27.247	22.18	22.769	372	365	344	628	593	516	IL17D	interleukin 17D [Source:HGNC Symbol;Acc:HGNC:5984]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04657//IL-17 signaling pathway	K05492;K05492;K05492;K05492	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity;GO:0048018//receptor ligand activity	GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1903707//negative regulation of hemopoiesis	--
ENSG00000172459	0	0	0	0	0	0	0	0	0	0	0	0	OR5AR1	olfactory receptor family 5 subfamily AR member 1 [Source:HGNC Symbol;Acc:HGNC:15260]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005507//copper ion binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172461	0.015	0.004	0	0.005	0.013	0	4	1	0	1	3	0	FUT9	fucosyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:4020]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K03663;K03663;K03663;K03663	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0007399//nervous system development;GO:0009312//oligosaccharide biosynthetic process;GO:0010976//positive regulation of neuron projection development;GO:0030182//neuron differentiation;GO:0033692//cellular polysaccharide biosynthetic process;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:1903037//regulation of leukocyte cell-cell adhesion;GO:1903236//regulation of leukocyte tethering or rolling	--
ENSG00000172464	0	0	0	0	0	0	0	0	0	0	0	0	OR5AP2	olfactory receptor family 5 subfamily AP member 2 [Source:HGNC Symbol;Acc:HGNC:15258]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172465	17.395	16.319	16.593	15.576	13.956	15.476	389	370	273	263	241	264	TCEAL1	transcription elongation factor A like 1 [Source:HGNC Symbol;Acc:HGNC:11616]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0050699//WW domain binding	-	--
ENSG00000172466	24.707	20.287	21.98	18.024	18.632	24.069	3201	2670	2122	1743	2053	2288	ZNF24	zinc finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13032]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0042552//myelination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000172468	0	0	0	0	0	0	0	0	0	0	0	0	HSFY1	heat shock transcription factor Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:18568]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000172469	7.582	5.126	5.701	5.525	5.135	6.607	710	448	389	381	386	454	MANEA	mannosidase endo-alpha [Source:HGNC Symbol;Acc:HGNC:21072]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004559//alpha-mannosidase activity;GO:0004569//glycoprotein endo-alpha-1,2-mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	-	--
ENSG00000172476	0.231	0.125	0.23	0.173	0.321	0.127	15	6	11	7	15	6	RAB40A	"RAB40A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18283]"	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0072659//protein localization to plasma membrane	--
ENSG00000172478	0	0.024	0	0	0	0	0	1	0	0	0	0	MAB21L4	mab-21 like 4 [Source:HGNC Symbol;Acc:HGNC:26216]	-	-	-	-	-	-	-	--
ENSG00000172482	0.017	0	0.045	0.067	0	0	1	0	2	3	0	0	AGXT	alanine--glyoxylate and serine--pyruvate aminotransferase [Source:HGNC Symbol;Acc:HGNC:341]	Metabolism;Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Transport and catabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04146//Peroxisome;ko00260//Glycine, serine and threonine metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K00830;K00830;K00830;K00830;K00830;K00830	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0004760//serine-pyruvate transaminase activity;GO:0005515//protein binding;GO:0008453//alanine-glyoxylate transaminase activity;GO:0008483//transaminase activity;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association	"GO:0006563//L-serine metabolic process;GO:0007219//Notch signaling pathway;GO:0009436//glyoxylate catabolic process;GO:0019265//glycine biosynthetic process, by transamination of glyoxylate;GO:0019448//L-cysteine catabolic process;GO:0042853//L-alanine catabolic process;GO:0046487//glyoxylate metabolic process;GO:0046724//oxalic acid secretion"	--
ENSG00000172487	0	0	0	0	0	0	0	0	0	0	0	0	OR8J1	olfactory receptor family 8 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:14855]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172489	0	0	0	0	0	0	0	0	0	0	0	0	OR5T3	olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172493	22.616	24.033	18.412	16.666	19.94	17.515	3567	3526	2173	1875	2680	1974	AFF1	AF4/FMR2 family member 1 [Source:HGNC Symbol;Acc:HGNC:7135]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15184	GO:0005634//nucleus;GO:0008023//transcription elongation factor complex;GO:0032783//super elongation complex;GO:0043227//membrane-bounded organelle	GO:0005515//protein binding	GO:0010468//regulation of gene expression	AF-4
ENSG00000172497	0	0	0	0	0	0	0	0	0	0	0	0	ACOT12	acyl-CoA thioesterase 12 [Source:HGNC Symbol;Acc:HGNC:24436]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00620//Pyruvate metabolism	K01067;K01067	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	GO:0003986//acetyl-CoA hydrolase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0036042//long-chain fatty acyl-CoA binding;GO:0042802//identical protein binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006084//acetyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000172500	31.072	34.807	32.954	36.145	34.327	33.218	848	938	640	719	795	656	FIBP	FGF1 intracellular binding protein [Source:HGNC Symbol;Acc:HGNC:3705]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0017134//fibroblast growth factor binding	GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0070527//platelet aggregation	--
ENSG00000172508	7.779	8.646	8.888	11.1	12.545	11.344	638	715	540	676	871	679	CARNS1	carnosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:29268]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00410//beta-Alanine metabolism;ko00340//Histidine metabolism	K14755;K14755;K14755;K14755	GO:0005575//cellular_component;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0047730//carnosine synthase activity;GO:0102102//homocarnosine synthase activity	GO:0006548//histidine catabolic process;GO:0035499//carnosine biosynthetic process	--
ENSG00000172519	0	0	0	0	0	0	0	0	0	0	0	0	OR10H5	olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000172530	8.403	5.441	6.542	6.556	5.557	6.706	285	197	183	170	173	160	BANP	BTG3 associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:13450]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0034504//protein localization to nucleus;GO:0042177//negative regulation of protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000172531	50.078	52.198	52.11	68.825	59.379	59.405	1477.91	1541.86	1130.92	1495	1480.59	1279.85	PPP1CA	protein phosphatase 1 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9281]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Genetic Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Cell motility;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Substance dependence;Signal transduction;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine and metabolic disease;Translation;Sensory system;Substance dependence;Nervous system	ko05168//Herpes simplex virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04931//Insulin resistance;ko03015//mRNA surveillance pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269	"GO:0000164//protein phosphatase type 1 complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0042587//glycogen granule;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0070062//extracellular exosome;GO:0072357//PTW/PP1 phosphatase complex;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse"	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043021//ribonucleoprotein complex binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0005981//regulation of glycogen catabolic process;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0010288//response to lead ion;GO:0016311//dephosphorylation;GO:0030324//lung development;GO:0032091//negative regulation of protein binding;GO:0032922//circadian regulation of gene expression;GO:0035970//peptidyl-threonine dephosphorylation;GO:0036496//regulation of translational initiation by eIF2 alpha dephosphorylation;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051301//cell division;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0070262//peptidyl-serine dephosphorylation;GO:0098609//cell-cell adhesion;GO:1904886//beta-catenin destruction complex disassembly;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000172534	10.757	11.792	12.173	11.293	12.711	13.028	1966	2171	1646	1535	1962	1729	HCFC1	host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K14966	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0035097//histone methyltransferase complex;GO:0043025//neuronal cell body;GO:0044545//NSL complex;GO:0044665//MLL1/2 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0010628//positive regulation of gene expression;GO:0019046//release from viral latency;GO:0043254//regulation of protein-containing complex assembly;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045787//positive regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0051568//histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000172538	0	0	0	0	0	0	0	0	0	0	0	0	FAM170B	family with sequence similarity 170 member B [Source:HGNC Symbol;Acc:HGNC:19736]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002081//outer acrosomal membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0009566//fertilization;GO:0080154//regulation of fertilization;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000172543	0	0	0	0	0	0	0	0	0	0	0	0	CTSW	cathepsin W [Source:HGNC Symbol;Acc:HGNC:2546]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K08569;K08569	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0031089//platelet dense granule lumen	GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006955//immune response;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000172548	0.438	0.584	0.233	0.253	0.278	0.236	28	32	11	12	13	11	NIPAL4	NIPA like domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28018]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015693//magnesium ion transport;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000172551	0	0	0	0	3.294	0	0	0	0	0	28	0	MUCL1	mucin like 1 [Source:HGNC Symbol;Acc:HGNC:30588]	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000172554	0	0	0	0	0	0	0	0	0	0	0	0	SNTG2	syntrophin gamma 2 [Source:HGNC Symbol;Acc:HGNC:13741]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016013//syntrophin complex;GO:0016020//membrane;GO:0042383//sarcolemma	GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0097109//neuroligin family protein binding	GO:0007417//central nervous system development	--
ENSG00000172568	0	0	0	0.037	0	0	0	0	0	1.19	0	0	FNDC9	fibronectin type III domain containing 9 [Source:HGNC Symbol;Acc:HGNC:33547]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000172572	0.487	0.484	0.533	0.318	0.407	0.35	126	126	102	61	89	66	PDE3A	phosphodiesterase 3A [Source:HGNC Symbol;Acc:HGNC:8778]	Metabolism;Environmental Information Processing;Environmental Information Processing;Metabolism;Human Diseases;Organismal Systems	Global and overview maps;Signal transduction;Signal transduction;Nucleotide metabolism;Substance dependence;Endocrine system	ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04924//Renin secretion	K19021;K19021;K19021;K19021;K19021;K19021	GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004119//cGMP-inhibited cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0001556//oocyte maturation;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009410//response to xenobiotic stimulus;GO:0019933//cAMP-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0040020//regulation of meiotic nuclear division;GO:0043066//negative regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0043117//positive regulation of vascular permeability;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0060282//positive regulation of oocyte development;GO:0071321//cellular response to cGMP;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000172575	0.261	0.209	0.21	0.225	0.346	0.236	25	19	13	8	24	16	RASGRP1	RAS guanyl releasing protein 1 [Source:HGNC Symbol;Acc:HGNC:9878]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Immune system;Immune system;Cancer: overview	ko05200//Pathways in cancer;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04611//Platelet activation;ko04660//T cell receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K04350;K04350;K04350;K04350;K04350;K04350	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019992//diacylglycerol binding;GO:0031210//phosphatidylcholine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0002437//inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0030101//natural killer cell activation;GO:0030154//cell differentiation;GO:0032252//secretory granule localization;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0042098//T cell proliferation;GO:0042100//B cell proliferation;GO:0042110//T cell activation;GO:0042113//B cell activation;GO:0043303//mast cell degranulation;GO:0043406//positive regulation of MAP kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046330//positive regulation of JNK cascade;GO:0046579//positive regulation of Ras protein signal transduction;GO:0047496//vesicle transport along microtubule;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090630//activation of GTPase activity	--
ENSG00000172578	0	0	0	0	0.01	0	0	0	0	0	1	0	KLHL6	kelch like family member 6 [Source:HGNC Symbol;Acc:HGNC:18653]	-	-	-	-	-	GO:0005515//protein binding	GO:0002467//germinal center formation;GO:0009617//response to bacterium;GO:0050853//B cell receptor signaling pathway	--
ENSG00000172586	15.435	15.743	20.584	16.011	15.79	16.83	274	285	271	211	237	220	CHCHD1	coiled-coil-helix-coiled-coil-helix domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23518]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0032543//mitochondrial translation	--
ENSG00000172590	15.462	15.096	20.704	19.618	15.925	13.802	231	267	231	222	192	168	MRPL52	mitochondrial ribosomal protein L52 [Source:HGNC Symbol;Acc:HGNC:16655]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000172594	6.896	6.316	5.816	4.507	5.149	5.194	252	232	157	122	159	138	SMPDL3A	sphingomyelin phosphodiesterase acid like 3A [Source:HGNC Symbol;Acc:HGNC:17389]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006685//sphingomyelin catabolic process;GO:0009143//nucleoside triphosphate catabolic process	--
ENSG00000172602	0.146	0.464	0.197	0.079	0.276	0.12	5	16	5	2	8	3	RND1	Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07531	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007162//negative regulation of cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016322//neuron remodeling;GO:0016477//cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization	--
ENSG00000172613	3.563	2.644	3.806	6.534	4.701	4.527	116.09	94.14	80.08	127	131.41	108.15	RAD9A	RAD9 checkpoint clamp component A [Source:HGNC Symbol;Acc:HGNC:9827]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K10994	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030896//checkpoint clamp complex	GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0008853//exodeoxyribonuclease III activity;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0042826//histone deacetylase binding	GO:0000076//DNA replication checkpoint signaling;GO:0000077//DNA damage checkpoint signaling;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0071479//cellular response to ionizing radiation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	--
ENSG00000172638	90.429	95.657	93.187	96.939	87.858	77.229	3341	3504	2534	2592	2780	2044	EFEMP2	EGF containing fibulin extracellular matrix protein 2 [Source:HGNC Symbol;Acc:HGNC:3219]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071953//elastic fiber;GO:1903561//extracellular vesicle	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042803//protein homodimerization activity	GO:0035904//aorta development;GO:0048251//elastic fiber assembly;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0097084//vascular associated smooth muscle cell development;GO:1904026//regulation of collagen fibril organization;GO:1904028//positive regulation of collagen fibril organization;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904831//positive regulation of aortic smooth muscle cell differentiation;GO:1905609//positive regulation of smooth muscle cell-matrix adhesion	--
ENSG00000172640	0	0	0	0	0	0	0	0	0	0	0	0	OR10AD1	olfactory receptor family 10 subfamily AD member 1 [Source:HGNC Symbol;Acc:HGNC:14819]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172650	0.993	0.907	1.559	1.181	0.572	0.747	53.53	46.82	43.69	49.32	27	30.66	AGAP5	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 [Source:HGNC Symbol;Acc:HGNC:23467]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000172661	16.343	16.719	13.919	12.71	13.031	13.365	1524.69	1597.9	977.59	896.78	1041.81	923.33	WASHC2C	WASH complex subunit 2C [Source:HGNC Symbol;Acc:HGNC:23414]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18462	GO:0005730//nucleolus;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071203//WASH complex	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1901981//phosphatidylinositol phosphate binding;GO:1905394//retromer complex binding"	"GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0032456//endocytic recycling;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0036010//protein localization to endosome;GO:0042147//retrograde transport, endosome to Golgi;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:2000813//negative regulation of barbed-end actin filament capping"	--
ENSG00000172663	7.895	5.798	7.784	8.022	7.802	10.385	194	177	153	155	182	156	TMEM134	transmembrane protein 134 [Source:HGNC Symbol;Acc:HGNC:26142]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000172667	4.712	4.087	5.124	3.623	3.989	4.844	787	690	572	448	539	544	ZMAT3	zinc finger matrin-type 3 [Source:HGNC Symbol;Acc:HGNC:29983]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10137	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0015031//protein transport;GO:0040008//regulation of growth	--
ENSG00000172671	2.853	3.266	2.914	2.545	1.563	2.767	205	228	168	147	103	136	ZFAND4	zinc finger AN1-type containing 4 [Source:HGNC Symbol;Acc:HGNC:23504]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000172673	0	0	0	0	0	0	0	0	0	0	0	0	THEMIS	thymocyte selection associated [Source:HGNC Symbol;Acc:HGNC:21569]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0008180//COP9 signalosome	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0043368//positive T cell selection;GO:0043383//negative T cell selection;GO:0050852//T cell receptor signaling pathway	--
ENSG00000172680	0	0	0	0	0	0	0	0	0	0	0	0	MOS	"MOS proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:7199]"	Cellular Processes;Cellular Processes;Organismal Systems	Cell motility;Cell growth and death;Endocrine system	ko04810//Regulation of actin cytoskeleton;ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K04367;K04367;K04367	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0000212//meiotic spindle organization;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0040020//regulation of meiotic nuclear division;GO:0043410//positive regulation of MAPK cascade;GO:0046777//protein autophosphorylation;GO:0051296//establishment of meiotic spindle orientation;GO:1902103//negative regulation of metaphase/anaphase transition of meiotic cell cycle	--
ENSG00000172687	4.707	3.224	2.941	5.07	3.08	3.461	213	171	94	136	144	130	ZNF738	zinc finger protein 738 [Source:HGNC Symbol;Acc:HGNC:32469]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity	"GO:0000209//protein polyubiquitination;GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000172689	0	0	0	0	0	0	0	0	0	0	0	0	MS4A10	membrane spanning 4-domains A10 [Source:HGNC Symbol;Acc:HGNC:13368]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000172716	0.678	0.529	0.549	0.116	0.266	0.097	44.81	56	16.25	7	22.92	7.19	SLFN11	schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0090734//site of DNA damage	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0002376//immune system process;GO:0006974//cellular response to DNA damage stimulus;GO:0008156//negative regulation of DNA replication;GO:0010942//positive regulation of cell death;GO:0043111//replication fork arrest;GO:0051607//defense response to virus;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000172717	0	0	0	0	0	0	0	0	0	0	0	0	FAM71D	family with sequence similarity 71 member D [Source:HGNC Symbol;Acc:HGNC:20101]	-	-	-	-	GO:0097225//sperm midpiece	-	GO:0030317//flagellated sperm motility	--
ENSG00000172724	0	0	0	0	0.167	0	0	0	0	0	2	0	CCL19	C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05512;K05512;K05512;K05512	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031732//CCR7 chemokine receptor binding;GO:0031735//CCR10 chemokine receptor binding;GO:0042379//chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0001768//establishment of T cell polarity;GO:0001771//immunological synapse formation;GO:0002407//dendritic cell chemotaxis;GO:0002408//myeloid dendritic cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009615//response to virus;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0016477//cell migration;GO:0030593//neutrophil chemotaxis;GO:0031295//T cell costimulation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034695//response to prostaglandin E;GO:0042102//positive regulation of T cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0045807//positive regulation of endocytosis;GO:0045860//positive regulation of protein kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0048247//lymphocyte chemotaxis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048469//cell maturation;GO:0050921//positive regulation of chemotaxis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051897//positive regulation of protein kinase B signaling;GO:0060326//cell chemotaxis;GO:0060491//regulation of cell projection assembly;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071731//response to nitric oxide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0097029//mature conventional dendritic cell differentiation;GO:0098586//cellular response to virus;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000147//positive regulation of cell motility;GO:2000549//positive regulation of dendritic cell dendrite assembly;GO:2000669//negative regulation of dendritic cell apoptotic process	--
ENSG00000172725	53.059	56.851	60.408	72.715	68.686	60.675	1570.87	1640.7	1221.46	1552.49	1607.34	1213.37	CORO1B	coronin 1B [Source:HGNC Symbol;Acc:HGNC:2253]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0031252//cell leading edge;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0003779//actin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0071933//Arp2/3 complex binding	GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0031529//ruffle organization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0035767//endothelial cell chemotaxis;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0042060//wound healing;GO:0051017//actin filament bundle assembly;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0090135//actin filament branching;GO:1902463//protein localization to cell leading edge;GO:2000394//positive regulation of lamellipodium morphogenesis	--
ENSG00000172728	4.784	4.203	4.458	3.791	3.721	3.781	335	311	230	201	222	195	FUT10	fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0006457//protein folding;GO:0006486//protein glycosylation;GO:0006605//protein targeting;GO:0007399//nervous system development;GO:0009566//fertilization;GO:0021799//cerebral cortex radially oriented cell migration;GO:0030097//hemopoiesis;GO:0036065//fucosylation;GO:0036071//N-glycan fucosylation;GO:0036445//neuronal stem cell division;GO:0042060//wound healing;GO:0042355//L-fucose catabolic process;GO:0097150//neuronal stem cell population maintenance	--
ENSG00000172731	40.294	41.322	39.44	71.454	62.561	68.321	2473	2551	1779	3231	3237	3033	LRRC20	leucine rich repeat containing 20 [Source:HGNC Symbol;Acc:HGNC:23421]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000172732	11.618	10.326	11.433	15.475	13.709	17.285	519	461	383	496	520	544	MUS81	MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K08991;K08991	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043596//nuclear replication fork;GO:0048476//Holliday junction resolvase complex;GO:1905347//endodeoxyribonuclease complex	GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0048257//3'-flap endonuclease activity	"GO:0000712//resolution of meiotic recombination intermediates;GO:0000727//double-strand break repair via break-induced replication;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0033687//osteoblast proliferation;GO:0072429//response to intra-S DNA damage checkpoint signaling"	--
ENSG00000172733	2.234	2.005	2.69	2.47	1.52	2.121	110	100	102	93	63	76	PURG	purine rich element binding protein G [Source:HGNC Symbol;Acc:HGNC:17930]	-	-	-	-	GO:0005634//nucleus;GO:0110165//cellular anatomical entity	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0032422//purine-rich negative regulatory element binding"	GO:0006357//regulation of transcription by RNA polymerase II	Others
ENSG00000172738	0.506	0.428	0.2	0.308	0.419	0.512	21	19.07	6	8	15.42	16	TMEM217	transmembrane protein 217 [Source:HGNC Symbol;Acc:HGNC:21238]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000172742	0	0	0	0	0	0	0	0	0	0	0	0	OR4D9	olfactory receptor family 4 subfamily D member 9 [Source:HGNC Symbol;Acc:HGNC:15178]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172748	1.297	0.981	1.08	1.131	0.694	0.667	64	55	33	29	32	28	ZNF596	zinc finger protein 596 [Source:HGNC Symbol;Acc:HGNC:27268]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000172752	0	0.016	0	0	0.097	0	0	3	0	0	3	0	COL6A5	collagen type VI alpha 5 chain [Source:HGNC Symbol;Acc:HGNC:26674]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K06238;K06238;K06238;K06238;K06238	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization	--
ENSG00000172757	329.493	340.001	342.564	383.369	355.039	329.816	7614	7916	5820	6425	6921	5536	CFL1	cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874]	Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Cell motility;Infectious disease: viral;Development and regeneration;Immune system;Infectious disease: bacterial	ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis;ko05133//Pertussis	K05765;K05765;K05765;K05765;K05765	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030027//lamellipodium;GO:0031258//lamellipodium membrane;GO:0031982//vesicle;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0007266//Rho protein signal transduction;GO:0009615//response to virus;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0030042//actin filament depolymerization;GO:0030043//actin filament fragmentation;GO:0040019//positive regulation of embryonic development;GO:0043066//negative regulation of apoptotic process;GO:0044794//positive regulation by host of viral process;GO:0048870//cell motility;GO:0051014//actin filament severing;GO:0051293//establishment of spindle localization;GO:0061001//regulation of dendritic spine morphogenesis	--
ENSG00000172765	4.197	4.27	3.131	2.788	16.414	3.655	538	526	302	270	354	328	TMCC1	transmembrane and coiled-coil domain family 1 [Source:HGNC Symbol;Acc:HGNC:29116]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0140284//endoplasmic reticulum-endosome membrane contact site	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007029//endoplasmic reticulum organization;GO:0016197//endosomal transport;GO:0090148//membrane fission;GO:0097750//endosome membrane tubulation;GO:0140285//endosome fission	--
ENSG00000172766	2.182	1.416	1.574	1.468	2.294	1.706	174	122	94	93	160	104	NAA16	"N-alpha-acetyltransferase 16, NatA auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:26164]"	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031415//NatA complex;GO:0070062//extracellular exosome	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0016407//acetyltransferase activity;GO:0043022//ribosome binding	"GO:0006474//N-terminal protein amino acid acetylation;GO:0017196//N-terminal peptidyl-methionine acetylation;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050821//protein stabilization"	--
ENSG00000172769	0	0	0	0	0	0	0	0	0	0	0	0	OR5B3	olfactory receptor family 5 subfamily B member 3 [Source:HGNC Symbol;Acc:HGNC:8324]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172771	0.563	0.583	0.671	0.487	0.239	0.093	25	26	22	16	9	3	EFCAB12	EF-hand calcium binding domain 12 [Source:HGNC Symbol;Acc:HGNC:28061]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000172772	0	0	0	0	0	0	0	0	0	0	0	0	OR10W1	olfactory receptor family 10 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:15139]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000172775	38.904	35.074	40.679	36.882	37.063	32.472	1175	1119	931	797	944	705	PSME3IP1	proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0032091//negative regulation of protein binding;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000172780	2.871	4.449	6.433	3.133	6.436	3.89	126.65	255.41	227.01	148.15	295.41	262.91	RAB43	"RAB43, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:19983]"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0019068//virion assembly;GO:0035526//retrograde transport, plasma membrane to Golgi;GO:0071346//cellular response to interferon-gamma;GO:0090382//phagosome maturation;GO:1901998//toxin transport"	--
ENSG00000172782	0	0	0	0	0	0	0	0	0	0	0	0	FADS6	fatty acid desaturase 6 [Source:HGNC Symbol;Acc:HGNC:30459]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016491//oxidoreductase activity	GO:0006629//lipid metabolic process	--
ENSG00000172785	12.054	12.396	11.941	12.707	10.853	12.888	416.95	396.71	284.23	303.14	303.03	294.21	CBWD1	COBW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17134]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000172789	0	0	0	0	0	0	0	0	0	0	0	0	HOXC5	homeobox C5 [Source:HGNC Symbol;Acc:HGNC:5127]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000172794	0.305	0.189	0.628	0.673	0.722	0.629	16	9	21	27	32	24	RAB37	"RAB37, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30268]"	-	-	-	-	GO:0005768//endosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0015031//protein transport	--
ENSG00000172795	6.124	5.141	5.159	3.362	4.786	4.76	1031	849	613	490	620	609	DCP2	decapping mRNA 2 [Source:HGNC Symbol;Acc:HGNC:24452]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12613	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0030054//cell junction;GO:0036464//cytoplasmic ribonucleoprotein granule	"GO:0003723//RNA binding;GO:0004534//5'-3' exoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016896//exoribonuclease activity, producing 5'-phosphomonoesters;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0070034//telomerase RNA binding"	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006402//mRNA catabolic process;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0043488//regulation of mRNA stability;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0071044//histone mRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1904872//regulation of telomerase RNA localization to Cajal body"	--
ENSG00000172803	1.262	1.313	1.281	0.813	1.358	1.419	44	46	33	21	40	36	SNX32	sorting nexin 32 [Source:HGNC Symbol;Acc:HGNC:26423]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17920	GO:0005768//endosome;GO:0005829//cytosol	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding	"GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000172809	156.149	158.199	138.951	180.926	123.381	135.903	1474	1472	986	1265	969	950	RPL38	ribosomal protein L38 [Source:HGNC Symbol;Acc:HGNC:10349]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02923;K02923	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0033291//eukaryotic 80S initiation complex;GO:0042788//polysomal ribosome;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006417//regulation of translation;GO:0007605//sensory perception of sound;GO:0022618//ribonucleoprotein complex assembly;GO:0034463//90S preribosome assembly;GO:0042474//middle ear morphogenesis;GO:0048318//axial mesoderm development	--
ENSG00000172817	3.793	2.449	1.837	1.954	2.126	1.856	587	381	210	224	278	209	CYP7B1	cytochrome P450 family 7 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2652]	Metabolism;Metabolism	Lipid metabolism;Lipid metabolism	ko00140//Steroid hormone biosynthesis;ko00120//Primary bile acid biosynthesis	K07430;K07430	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0008396//oxysterol 7-alpha-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0033782//24-hydroxycholesterol 7alpha-hydroxylase activity;GO:0033783//25-hydroxycholesterol 7alpha-hydroxylase activity;GO:0046872//metal ion binding;GO:0047092//27-hydroxycholesterol 7-alpha-monooxygenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035754//B cell chemotaxis;GO:0042632//cholesterol homeostasis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060740//prostate gland epithelium morphogenesis	--
ENSG00000172818	0	0	0.022	0.044	0.038	0	0	0	1	2	2	0	OVOL1	ovo like transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:8525]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007498//mesoderm development;GO:0008544//epidermis development;GO:0009913//epidermal cell differentiation;GO:0043588//skin development;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:1901994//negative regulation of meiotic cell cycle phase transition;GO:2000647//negative regulation of stem cell proliferation"	zf-C2H2
ENSG00000172819	11.339	12.927	11.419	11.299	10.859	14.443	617	678	487	432	525	575	RARG	retinoic acid receptor gamma [Source:HGNC Symbol;Acc:HGNC:9866]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046965//retinoid X receptor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001843//neural tube closure;GO:0002063//chondrocyte development;GO:0002068//glandular epithelial cell development;GO:0003417//growth plate cartilage development;GO:0003430//growth plate cartilage chondrocyte growth;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008361//regulation of cell size;GO:0009755//hormone-mediated signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0031076//embryonic camera-type eye development;GO:0031641//regulation of myelination;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032526//response to retinoic acid;GO:0035116//embryonic hindlimb morphogenesis;GO:0035264//multicellular organism growth;GO:0043065//positive regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0045596//negative regulation of cell differentiation;GO:0045637//regulation of myeloid cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048048//embryonic eye morphogenesis;GO:0048384//retinoic acid receptor signaling pathway;GO:0048608//reproductive structure development;GO:0048732//gland development;GO:0060070//canonical Wnt signaling pathway;GO:0060173//limb development;GO:0060324//face development;GO:0060348//bone development;GO:0060349//bone morphogenesis;GO:0060429//epithelium development;GO:0060534//trachea cartilage development;GO:0060740//prostate gland epithelium morphogenesis;GO:0061037//negative regulation of cartilage development;GO:0070384//Harderian gland development;GO:0071300//cellular response to retinoic acid;GO:1990830//cellular response to leukemia inhibitory factor"	THR-like
ENSG00000172824	1.014	0.886	1.011	1.674	1.421	1.379	41	37	32	51	53	44	CES4A	carboxylesterase 4A [Source:HGNC Symbol;Acc:HGNC:26741]	-	-	-	-	GO:0005576//extracellular region	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	-	--
ENSG00000172828	0.225	0.113	0.297	0.051	0.193	0.134	18	9	13	3	13	6	CES3	carboxylesterase 3 [Source:HGNC Symbol;Acc:HGNC:1865]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0080030//methyl indole-3-acetate esterase activity	GO:0006805//xenobiotic metabolic process;GO:0034383//low-density lipoprotein particle clearance	--
ENSG00000172830	12.317	12.934	13.489	16.816	17.139	15.57	682	691	559	676	801	621	SSH3	slingshot protein phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:30581]	Cellular Processes;Organismal Systems	Cell motility;Development and regeneration	ko04810//Regulation of actin cytoskeleton;ko04360//Axon guidance	K05766;K05766	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030837//negative regulation of actin filament polymerization;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000172831	18.339	18.905	18.342	20.397	19.339	16.819	1282	1350	957	1044	1184	867	CES2	carboxylesterase 2 [Source:HGNC Symbol;Acc:HGNC:1864]	Metabolism	Xenobiotics biodegradation and metabolism	ko00983//Drug metabolism - other enzymes	K03927	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0016787//hydrolase activity;GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0080030//methyl indole-3-acetate esterase activity	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0009056//catabolic process	--
ENSG00000172840	6.137	8.276	8.61	6.76	8.778	7.271	663	612	493.79	544	607	587	PDP2	pyruvate dehyrogenase phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:30263]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:1904184//positive regulation of pyruvate dehydrogenase activity	--
ENSG00000172845	21.798	16.885	17.926	12.923	12.972	18.434	1795	1423	1124	805	955	1112	SP3	Sp3 transcription factor [Source:HGNC Symbol;Acc:HGNC:11208]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0017053//transcription repressor complex;GO:0032993//protein-DNA complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001701//in utero embryonic development;GO:0001779//natural killer cell differentiation;GO:0001829//trophectodermal cell differentiation;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0030224//monocyte differentiation;GO:0030324//lung development;GO:0030851//granulocyte differentiation;GO:0043353//enucleate erythrocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048596//embryonic camera-type eye morphogenesis;GO:0048706//embryonic skeletal system development;GO:0060136//embryonic process involved in female pregnancy;GO:0060216//definitive hemopoiesis"	zf-C2H2
ENSG00000172867	0	0	0	0	0	0	0	0	0	0	0	0	KRT2	keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439]	-	-	-	-	GO:0001533//cornified envelope;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0030280//structural constituent of skin epidermis	GO:0003334//keratinocyte development;GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0031424//keratinization;GO:0032980//keratinocyte activation;GO:0043616//keratinocyte proliferation;GO:0045109//intermediate filament organization;GO:0045684//positive regulation of epidermis development;GO:0051546//keratinocyte migration	--
ENSG00000172869	7.918	4.817	5.036	3.352	4.082	5.356	1756	1123	859	575	790	863	DMXL1	Dmx like 1 [Source:HGNC Symbol;Acc:HGNC:2937]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K24155	GO:0043291//RAVE complex	GO:0005515//protein binding	GO:0007035//vacuolar acidification	--
ENSG00000172878	1.044	1.196	1.006	1.729	1.553	1.195	66	76	47	81	83	55	METAP1D	"methionyl aminopeptidase type 1D, mitochondrial [Source:HGNC Symbol;Acc:HGNC:32583]"	-	-	-	-	GO:0005739//mitochondrion	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0018206//peptidyl-methionine modification;GO:0031365//N-terminal protein amino acid modification;GO:0070084//protein initiator methionine removal	--
ENSG00000172888	5.726	4.24	4.581	4.195	4.753	4.453	623	541	391	308	441	348	ZNF621	zinc finger protein 621 [Source:HGNC Symbol;Acc:HGNC:24787]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000172889	3.084	3.592	3.768	4.975	3.917	3.411	82	96	74	98	88	66	EGFL7	EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007155//cell adhesion;GO:0030154//cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0048856//anatomical structure development	--
ENSG00000172890	12.492	15.157	14.167	18.163	16.815	15.79	684	841	528	753	774	555	NADSYN1	NAD synthetase 1 [Source:HGNC Symbol;Acc:HGNC:29832]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K01950;K01950	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003952//NAD+ synthase (glutamine-hydrolyzing) activity;GO:0004359//glutaminase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006807//nitrogen compound metabolic process;GO:0009435//NAD biosynthetic process;GO:0034627//'de novo' NAD biosynthetic process	--
ENSG00000172893	67.124	66.032	74.961	104.6	97.203	94.763	3633	3567	2962	4182	4412	3664	DHCR7	7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K00213;K00213	GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0009918//sterol delta7 reductase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0047598//7-dehydrocholesterol reductase activity;GO:0050661//NADP binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016126//sterol biosynthetic process;GO:0016132//brassinosteroid biosynthetic process;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0045540//regulation of cholesterol biosynthetic process	--
ENSG00000172901	0	0.013	0	0	0	0	0	1	0	0	0	0	LVRN	laeverin [Source:HGNC Symbol;Acc:HGNC:26904]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0043171//peptide catabolic process	--
ENSG00000172915	20.004	15.889	15.968	10.508	12.378	12.784	2700	2020	1346	919	1291	1110	NBEA	neurobeachin [Source:HGNC Symbol;Acc:HGNC:7648]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043226//organelle	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0008104//protein localization;GO:0061484//hematopoietic stem cell homeostasis	--
ENSG00000172922	27.472	25.438	22.945	29.564	29.028	34.195	919.09	923.9	728.07	835.44	874.56	936.91	RNASEH2C	ribonuclease H2 subunit C [Source:HGNC Symbol;Acc:HGNC:24116]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K10745	GO:0005634//nucleus;GO:0032299//ribonuclease H2 complex	GO:0005515//protein binding	GO:0006298//mismatch repair;GO:0006401//RNA catabolic process	--
ENSG00000172927	0	0	0	0	0	0.029	0	0	0	0	0	1	MYEOV	myeloma overexpressed [Source:HGNC Symbol;Acc:HGNC:7563]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000172932	7.329	8.519	7.625	9.286	8.512	10.048	324	380	241	295	299	324	ANKRD13D	ankyrin repeat domain 13D [Source:HGNC Symbol;Acc:HGNC:27880]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0140036//ubiquitin-dependent protein binding	GO:0002091//negative regulation of receptor internalization	--
ENSG00000172935	1.334	0.95	1.001	1.016	1.713	1.958	59	43	33	35	64	63	MRGPRF	MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000172936	9.957	10.486	10.318	10.036	10.626	11.095	570	584	426	416	507	457	MYD88	MYD88 innate immune signal transduction adaptor [Source:HGNC Symbol;Acc:HGNC:7562]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: parasitic	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis;ko05134//Legionellosis;ko05144//Malaria	K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729;K04729	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0032991//protein-containing complex	GO:0003953//NAD+ nucleosidase activity;GO:0005102//signaling receptor binding;GO:0005121//Toll binding;GO:0005123//death receptor binding;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding;GO:0035325//Toll-like receptor binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0070976//TIR domain binding	GO:0002238//response to molecule of fungal origin;GO:0002269//leukocyte activation involved in inflammatory response;GO:0002283//neutrophil activation involved in immune response;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007254//JNK cascade;GO:0008063//Toll signaling pathway;GO:0009615//response to virus;GO:0009682//induced systemic resistance;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0016064//immunoglobulin mediated immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0032494//response to peptidoglycan;GO:0032496//response to lipopolysaccharide;GO:0032675//regulation of interleukin-6 production;GO:0032680//regulation of tumor necrosis factor production;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032740//positive regulation of interleukin-17 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034158//toll-like receptor 8 signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050727//regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0070944//neutrophil-mediated killing of bacterium;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus;GO:0090557//establishment of endothelial intestinal barrier;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1902622//regulation of neutrophil migration;GO:2000338//regulation of chemokine (C-X-C motif) ligand 1 production;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000172938	0	0	0	0	0	0	0	0	0	0	0	0	MRGPRD	MAS related GPR family member D [Source:HGNC Symbol;Acc:HGNC:29626]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K08392	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000172939	12.027	11.508	12.385	12.046	11.332	12.154	1105	1073	857	836	897	825	OXSR1	oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007231//osmosensory signaling pathway;GO:0010820//positive regulation of T cell chemotaxis;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032879//regulation of localization;GO:0035556//intracellular signal transduction;GO:0038116//chemokine (C-C motif) ligand 21 signaling pathway;GO:0038146//chemokine (C-X-C motif) ligand 12 signaling pathway;GO:0046777//protein autophosphorylation;GO:0048583//regulation of response to stimulus;GO:0071476//cellular hypotonic response;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1990869//cellular response to chemokine	--
ENSG00000172940	0	0	0	0.039	0	0	0	0	0	1	0	0	SLC22A13	solute carrier family 22 member 13 [Source:HGNC Symbol;Acc:HGNC:8494]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0022857//transmembrane transporter activity;GO:0090416//nicotinate transmembrane transporter activity	GO:0002854//positive regulation of T cell mediated cytotoxicity directed against tumor cell target;GO:0015747//urate transport;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0045922//negative regulation of fatty acid metabolic process;GO:0055085//transmembrane transport;GO:2001142//nicotinate transport	--
ENSG00000172943	5.961	6.302	8.145	7.285	6.199	6.823	701	675	517	522	612	550	PHF8	PHD finger protein 8 [Source:HGNC Symbol;Acc:HGNC:20672]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031965//nuclear membrane	GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0035064//methylated histone binding;GO:0035575//histone H4-methyl-lysine-20 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0071558//histone H3-tri/di-methyl-lysine-27 demethylase activity;GO:0140680//histone H3-di/monomethyl-lysine-36 demethylase activity;GO:0140683//histone H3-di/monomethyl-lysine-9 demethylase activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0007049//cell cycle;GO:0007420//brain development;GO:0033169//histone H3-K9 demethylation;GO:0035574//histone H4-K20 demethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0061188//negative regulation of ribosomal DNA heterochromatin assembly;GO:0070544//histone H3-K36 demethylation;GO:0071557//histone H3-K27 demethylation"	--
ENSG00000172954	2.87	3.497	4.425	1.923	3.243	3.771	256	250	201	129	183	186	LCLAT1	lysocardiolipin acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26756]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K13513;K13513;K13513	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0035965//cardiolipin acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling	--
ENSG00000172955	0	0	0	0	0	0	0	0	0	0	0	0	ADH6	alcohol dehydrogenase 6 (class V) [Source:HGNC Symbol;Acc:HGNC:255]	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13952;K13952;K13952;K13952;K13952;K13952;K13952;K13952;K13952	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004745//NAD-retinol dehydrogenase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0046872//metal ion binding"	GO:0006069//ethanol oxidation;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0045471//response to ethanol	--
ENSG00000172967	0	0	0	0	0	0	0	0	0	0	0	0	XKR3	XK related 3 [Source:HGNC Symbol;Acc:HGNC:28778]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000172969	0	0	0	0	0	0	0	0	0	0	0	0	FRG2C	FSHD region gene 2 family member C [Source:HGNC Symbol;Acc:HGNC:33626]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000172977	19.292	18.862	20.047	22.685	20.881	18.047	687.91	752.1	603.93	630.56	677.44	499.09	KAT5	lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]	Human Diseases;Human Diseases	Infectious disease: viral;Neurodegenerative disease	ko05166//Human T-cell leukemia virus 1 infection;ko05017//Spinocerebellar ataxia	K11304;K11304	GO:0000123//histone acetyltransferase complex;GO:0000776//kinetochore;GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032777//Piccolo NuA4 histone acetyltransferase complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0097431//mitotic spindle pole	GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042393//histone binding;GO:0043998//H2A histone acetyltransferase activity;GO:0043999//histone acetyltransferase activity (H2A-K5 specific);GO:0046872//metal ion binding;GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0061733//peptide-lysine-N-acetyltransferase activity;GO:0140064//peptide crotonyltransferase activity;GO:0140065//peptide butyryltransferase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000132//establishment of mitotic spindle orientation;GO:0000724//double-strand break repair via homologous recombination;GO:0006289//nucleotide-excision repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007286//spermatid development;GO:0010212//response to ionizing radiation;GO:0010508//positive regulation of autophagy;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0016573//histone acetylation;GO:0018394//peptidyl-lysine acetylation;GO:0032703//negative regulation of interleukin-2 production;GO:0040008//regulation of growth;GO:0042149//cellular response to glucose starvation;GO:0042753//positive regulation of circadian rhythm;GO:0042981//regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0043977//histone H2A-K5 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051726//regulation of cell cycle;GO:0062033//positive regulation of mitotic sister chromatid segregation;GO:0071392//cellular response to estradiol stimulus;GO:0090398//cellular senescence;GO:1900051//positive regulation of histone exchange;GO:1901985//positive regulation of protein acetylation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:1905691//lipid droplet disassembly;GO:2000779//regulation of double-strand break repair"	--
ENSG00000172985	0.567	0.629	0.187	0.536	0.681	0.624	70	78	17	49	71	56	SH3RF3	SH3 domain containing ring finger 3 [Source:HGNC Symbol;Acc:HGNC:24699]	-	-	-	-	-	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0046328//regulation of JNK cascade;GO:0046330//positive regulation of JNK cascade;GO:0051865//protein autoubiquitination	--
ENSG00000172986	6.199	4.744	4.383	2.901	4.285	4.344	356	324	198	146	246	165	GXYLT2	glucoside xylosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:33383]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K13676	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035252//UDP-xylosyltransferase activity;GO:0140563//UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity"	GO:0016266//O-glycan processing	--
ENSG00000172987	0	0	0	0	0	0	0	0	0	0	0	0	HPSE2	heparanase 2 (inactive) [Source:HGNC Symbol;Acc:HGNC:18374]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko05205//Proteoglycans in cancer;ko00531//Glycosaminoglycan degradation	K07965;K07965;K07965	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031012//extracellular matrix	"GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030305//heparanase activity;GO:0043395//heparan sulfate proteoglycan binding"	GO:0006027//glycosaminoglycan catabolic process;GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0030198//extracellular matrix organization	--
ENSG00000172992	30.48	31.686	27.022	37.871	28.948	27.785	1067	1142	736	911	1025	813	DCAKD	dephospho-CoA kinase domain containing [Source:HGNC Symbol;Acc:HGNC:26238]	-	-	-	-	GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004140//dephospho-CoA kinase activity;GO:0005524//ATP binding	GO:0006796//phosphate-containing compound metabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation	--
ENSG00000172995	0	0.023	0	0.032	0	0	0	2	0	1	0	0	ARPP21	cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0008150//biological_process;GO:0034605//cellular response to heat	--
ENSG00000173011	26.433	22.268	25.296	23.832	27.045	23.127	1436	1383	1174	1197	1397	1046	TADA2B	transcriptional adaptor 2B [Source:HGNC Symbol;Acc:HGNC:30781]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070461//SAGA-type complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006282//regulation of DNA repair;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035065//regulation of histone acetylation;GO:0035066//positive regulation of histone acetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	MYB
ENSG00000173013	3.762	4.077	5.306	5.321	4.241	5.386	168	183	175	176	160	175	CCDC96	coiled-coil domain containing 96 [Source:HGNC Symbol;Acc:HGNC:26900]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0036064//ciliary basal body	GO:0005515//protein binding	GO:0060271//cilium assembly	--
ENSG00000173020	10.994	9.768	10.8	14.115	11.889	12.793	776	693	563	738	709	657	GRK2	G protein-coupled receptor kinase 2 [Source:HGNC Symbol;Acc:HGNC:289]	Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Sensory system;Transport and catabolism;Immune system;Nervous system;Substance dependence;Signal transduction	ko04740//Olfactory transduction;ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko04724//Glutamatergic synapse;ko05032//Morphine addiction;ko04340//Hedgehog signaling pathway	K00910;K00910;K00910;K00910;K00910;K00910	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0031755//Edg-2 lysophosphatidic acid receptor binding;GO:0047696//beta-adrenergic receptor kinase activity	GO:0002026//regulation of the force of heart contraction;GO:0002029//desensitization of G protein-coupled receptor signaling pathway;GO:0003108//negative regulation of the force of heart contraction by chemical signal;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007217//tachykinin receptor signaling pathway;GO:0007507//heart development;GO:0009966//regulation of signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019079//viral genome replication;GO:0031623//receptor internalization;GO:0033605//positive regulation of catecholamine secretion;GO:0043170//macromolecule metabolic process;GO:0045988//negative regulation of striated muscle contraction;GO:0046718//viral entry into host cell;GO:0060048//cardiac muscle contraction;GO:1901081//negative regulation of relaxation of smooth muscle	--
ENSG00000173039	31.704	27.979	38.611	33.133	36.505	39.634	1525	1383	1116	1170	1376	1212	RELA	"RELA proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9955]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Cancer: specific types;Immune system;Cancer: overview;Immune system;Aging;Cancer: specific types;Cancer: specific types;Infectious disease: bacterial;Cancer: specific types;Endocrine system;Transport and catabolism;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune disease;Immune system;Infectious disease: bacterial;Substance dependence;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04066//HIF-1 signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04211//Longevity regulating pathway;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05133//Pertussis;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05221//Acute myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko05321//Inflammatory bowel disease;ko04623//Cytosolic DNA-sensing pathway;ko05134//Legionellosis;ko05030//Cocaine addiction;ko01523//Antifolate resistance	K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735;K04735	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035525//NF-kappaB p50/p65 complex;GO:0071159//NF-kappaB complex;GO:0098978//glutamatergic synapse	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0042277//peptide binding;GO:0042301//phosphate ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042805//actinin binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0051059//NF-kappaB binding;GO:0071532//ankyrin repeat binding;GO:0140296//general transcription initiation factor binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001889//liver development;GO:0001942//hair follicle development;GO:0002357//defense response to tumor cell;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006968//cellular defense response;GO:0007218//neuropeptide signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008284//positive regulation of cell population proliferation;GO:0009617//response to bacterium;GO:0009887//animal organ morphogenesis;GO:0010033//response to organic substance;GO:0010224//response to UV-B;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0032479//regulation of type I interferon production;GO:0032495//response to muramyl dipeptide;GO:0032735//positive regulation of interleukin-12 production;GO:0032757//positive regulation of interleukin-8 production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0033234//negative regulation of protein sumoylation;GO:0034097//response to cytokine;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0035994//response to muscle stretch;GO:0038061//NIK/NF-kappaB signaling;GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0070301//cellular response to hydrogen peroxide;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0071222//cellular response to lipopolysaccharide;GO:0071223//cellular response to lipoteichoic acid;GO:0071224//cellular response to peptidoglycan;GO:0071316//cellular response to nicotine;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0099527//postsynapse to nucleus signaling pathway;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902004//positive regulation of amyloid-beta formation;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904385//cellular response to angiotensin;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:2000630//positive regulation of miRNA metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	RHD
ENSG00000173040	1.726	1.973	1.966	1.931	1.639	1.819	157	180	132	130	126	120	EVC2	EvC ciliary complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19747]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K19608	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0098797//plasma membrane protein complex	-	GO:0007224//smoothened signaling pathway	--
ENSG00000173041	5.738	5.078	4.935	4.015	4.435	5.378	355	314.37	221	183	230	236	ZNF680	zinc finger protein 680 [Source:HGNC Symbol;Acc:HGNC:26897]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000173064	7.531	8.022	7.986	6.422	7.443	7.371	2383	2478	1885	1523	1964	1721	HECTD4	HECT domain E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:26611]	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity	GO:0016567//protein ubiquitination	--
ENSG00000173065	10.824	11.883	11.707	10.261	12.337	10.223	941	1034	729	663	869	646	FAM222B	family with sequence similarity 222 member B [Source:HGNC Symbol;Acc:HGNC:25563]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000173068	1.238	1.17	1.39	1.614	1.629	1.314	209	189	141	150	173	141	BNC2	basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000182//rDNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0003416//endochondral bone growth;GO:0006355//regulation of transcription, DNA-templated;GO:0043586//tongue development;GO:0060021//roof of mouth development;GO:0060485//mesenchyme development"	zf-C2H2
ENSG00000173080	0	0	0	0	0	0	0	0	0	0	0	0	RXFP4	relaxin family peptide/INSL5 receptor 4 [Source:HGNC Symbol;Acc:HGNC:14666]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K08398;K08398	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:2000253//positive regulation of feeding behavior	--
ENSG00000173083	0.129	0.136	0.077	0.101	0.157	0.105	5	9	3	6	4	4	HPSE	heparanase [Source:HGNC Symbol;Acc:HGNC:5164]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko05205//Proteoglycans in cancer;ko00531//Glycosaminoglycan degradation	K07964;K07964;K07964	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0035580//specific granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	"GO:0004566//beta-glucuronidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030305//heparanase activity;GO:0045545//syndecan binding"	GO:0006029//proteoglycan metabolic process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010033//response to organic substance;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0030194//positive regulation of blood coagulation;GO:0030200//heparan sulfate proteoglycan catabolic process;GO:0030202//heparin metabolic process;GO:0033690//positive regulation of osteoblast proliferation;GO:0042060//wound healing;GO:0051797//regulation of hair follicle development;GO:0051798//positive regulation of hair follicle development;GO:0051897//positive regulation of protein kinase B signaling;GO:0060055//angiogenesis involved in wound healing;GO:0061028//establishment of endothelial barrier;GO:0061042//vascular wound healing;GO:0071806//protein transmembrane transport	--
ENSG00000173085	4.723	4.571	7.088	6.077	4.292	5.322	149	143	164	142	115	121	COQ2	"coenzyme Q2, polyprenyltransferase [Source:HGNC Symbol;Acc:HGNC:25223]"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K06125;K06125	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	"GO:0002083//4-hydroxybenzoate decaprenyltransferase activity;GO:0004659//prenyltransferase activity;GO:0008412//4-hydroxybenzoate octaprenyltransferase activity;GO:0016740//transferase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0047293//4-hydroxybenzoate nonaprenyltransferase activity"	GO:0006071//glycerol metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0008299//isoprenoid biosynthetic process	--
ENSG00000173093	0	0	0	0	0	0	0	0	0	0	0	0	CCDC63	coiled-coil domain containing 63 [Source:HGNC Symbol;Acc:HGNC:26669]	-	-	-	-	GO:0005930//axoneme	-	GO:0003341//cilium movement;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0036158//outer dynein arm assembly	--
ENSG00000173110	0.328	0.244	0.277	0.304	0.291	0.084	16	12	10	11	12	3	HSPA6	heat shock protein family A (Hsp70) member 6 [Source:HGNC Symbol;Acc:HGNC:5239]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0006986//response to unfolded protein;GO:0016192//vesicle-mediated transport;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000173113	77.979	81.031	84.834	105.585	81.701	93.512	1263	1295	1043.94	1284.65	1077.7	1116.41	TRMT112	tRNA methyltransferase activator subunit 11-2 [Source:HGNC Symbol;Acc:HGNC:26940]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008276//protein methyltransferase activity;GO:0046982//protein heterodimerization activity	GO:0006364//rRNA processing;GO:0018364//peptidyl-glutamine methylation;GO:0030488//tRNA methylation;GO:0031167//rRNA methylation;GO:0034968//histone lysine methylation;GO:0070476//rRNA (guanine-N7)-methylation;GO:2000234//positive regulation of rRNA processing	--
ENSG00000173114	0.385	0.206	0.224	0.259	0.195	0.295	25	15	12	14	12	9	LRRN3	leucine rich repeat neuronal 3 [Source:HGNC Symbol;Acc:HGNC:17200]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly	--
ENSG00000173120	14.989	14.476	15.754	14.594	14.849	14.356	2071	1947	1503	1383	1627	1403	KDM2A	lysine demethylase 2A [Source:HGNC Symbol;Acc:HGNC:13606]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051864//histone H3-methyl-lysine-36 demethylase activity;GO:0140680//histone H3-di/monomethyl-lysine-36 demethylase activity	GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0032259//methylation;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0070076//histone lysine demethylation;GO:0070544//histone H3-K36 demethylation	--
ENSG00000173124	0	0	0	0	0.108	0	0	0	0	0	3	0	ACSM6	acyl-CoA synthetase medium chain family member 6 [Source:HGNC Symbol;Acc:HGNC:31665]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0015645//fatty acid ligase activity;GO:0016874//ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000173137	2.08	1.468	3.067	3.063	2.12	3.114	85	60	87	69	73	85	ADCK5	aarF domain containing kinase 5 [Source:HGNC Symbol;Acc:HGNC:21738]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000173141	12.436	13.855	14.675	14.515	12.829	16.706	576	645	502	498	502	563	MRPL57	mitochondrial ribosomal protein L57 [Source:HGNC Symbol;Acc:HGNC:14514]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000173145	2.916	2.582	2.588	1.658	2.296	1.975	209	186	137	88	139	103	NOC3L	NOC3 like DNA replication regulator [Source:HGNC Symbol;Acc:HGNC:24034]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016607//nuclear speck	GO:0003682//chromatin binding;GO:0003723//RNA binding	GO:0006270//DNA replication initiation;GO:0045444//fat cell differentiation	--
ENSG00000173153	5.441	5.778	6.312	10.473	8.491	9.915	257	274	220.06	325.35	331.3	340.59	ESRRA	estrogen related receptor alpha [Source:HGNC Symbol;Acc:HGNC:3471]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030278//regulation of ossification;GO:0030522//intracellular receptor signaling pathway;GO:0032355//response to estradiol;GO:0042127//regulation of cell population proliferation;GO:0043401//steroid hormone mediated signaling pathway;GO:0045667//regulation of osteoblast differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051216//cartilage development;GO:1900078//positive regulation of cellular response to insulin stimulus"	ESR-like
ENSG00000173156	18.909	18.715	18.544	19.219	19.64	19.954	433	428	311	326	373	330	RHOD	ras homolog family member D [Source:HGNC Symbol;Acc:HGNC:670]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07530	GO:0000139//Golgi membrane;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005525//GTP binding;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0030335//positive regulation of cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0045785//positive regulation of cell adhesion;GO:0048041//focal adhesion assembly;GO:0050790//regulation of catalytic activity;GO:0051017//actin filament bundle assembly;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000173157	0	0	0	0	0	0	0	0	0	0	0	0	ADAMTS20	ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0009967//positive regulation of signal transduction;GO:0030198//extracellular matrix organization;GO:0043066//negative regulation of apoptotic process;GO:0045636//positive regulation of melanocyte differentiation;GO:0048070//regulation of developmental pigmentation	--
ENSG00000173163	16.781	16.605	16.001	17.175	17.127	13.412	242	239	170.01	184.06	209	141.04	COMMD1	copper metabolism domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23024]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0055037//recycling endosome	"GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008289//lipid binding;GO:0019871//sodium channel inhibitor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0006289//nucleotide-excision repair;GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048227//plasma membrane to endosome transport;GO:0055070//copper ion homeostasis;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000173166	4.331	4.369	4.661	5.553	3.966	4.212	579.17	518.97	456.85	315.43	383.73	391.34	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:HGNC Symbol;Acc:HGNC:14436]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K23488	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0031252//cell leading edge;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0048675//axon extension	--
ENSG00000173171	16.208	19.745	20.151	23.015	18.193	17.735	379	466	351	396	350	303	MTX1	metaxin 1 [Source:HGNC Symbol;Acc:HGNC:7504]	-	-	-	-	GO:0001401//SAM complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0140275//MIB complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization;GO:0007595//lactation;GO:0015031//protein transport;GO:0045040//protein insertion into mitochondrial outer membrane	--
ENSG00000173175	0.553	0.426	0.339	0.931	0.675	0.453	51	59	27	43	41	37	ADCY5	adenylate cyclase 5 [Source:HGNC Symbol;Acc:HGNC:236]	Metabolism;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Global and overview maps;Cancer: overview;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Substance dependence;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nervous system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Digestive system;Endocrine system;Endocrine system;Substance dependence;Aging;Endocrine system;Endocrine system;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko05030//Cocaine addiction"	K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045;K08045	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0045111//intermediate filament cytoskeleton	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding;GO:0008179//adenylate cyclase binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding	GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0003008//system process;GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007626//locomotory behavior;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0050885//neuromuscular process controlling balance;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0065008//regulation of biological quality;GO:1904322//cellular response to forskolin	--
ENSG00000173193	4.386	3.161	2.893	2.47	3.104	2.859	700	507	341	292	419	332	PARP14	poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003714//transcription corepressor activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:1990404//protein ADP-ribosylase activity	"GO:0002376//immune system process;GO:0006471//protein ADP-ribosylation;GO:0010629//negative regulation of gene expression;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0070212//protein poly-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation;GO:1902216//positive regulation of interleukin-4-mediated signaling pathway"	--
ENSG00000173198	0.054	0.036	0.146	0	0.043	0.049	3	2	6	0	2	2	CYSLTR1	cysteinyl leukotriene receptor 1 [Source:HGNC Symbol;Acc:HGNC:17451]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04322;K04322	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001631//cysteinyl leukotriene receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004974//leukotriene receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0002437//inflammatory response to antigenic stimulus;GO:0006816//calcium ion transport;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0045766//positive regulation of angiogenesis;GO:0045907//positive regulation of vasoconstriction;GO:0061737//leukotriene signaling pathway	--
ENSG00000173200	0.298	0.127	0.245	0.215	0.277	0.209	27.44	11.78	16.69	14.65	21.56	14.01	PARP15	poly(ADP-ribose) polymerase family member 15 [Source:HGNC Symbol;Acc:HGNC:26876]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003714//transcription corepressor activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0070403//NAD+ binding;GO:1990404//protein ADP-ribosylase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010629//negative regulation of gene expression;GO:0070212//protein poly-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation	--
ENSG00000173207	19.899	20.676	22.069	17.906	15.027	17.783	322	336	265	215	206	210	CKS1B	CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05222//Small cell lung cancer	K02219;K02219	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005654//nucleoplasm;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding;GO:0042393//histone binding;GO:0043130//ubiquitin binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0044772//mitotic cell cycle phase transition;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0050790//regulation of catalytic activity;GO:0051301//cell division"	--
ENSG00000173208	0.33	0.275	0.125	0.238	0.2	0.211	43	36	12	23	22	20	ABCD2	ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66]	Cellular Processes;Environmental Information Processing	Transport and catabolism;Membrane transport	ko04146//Peroxisome;ko02010//ABC transporters	K05676;K05676	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0047617//acyl-CoA hydrolase activity;GO:0140359//ABC-type transporter activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0007031//peroxisome organization;GO:0015910//long-chain fatty acid import into peroxisome;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0042760//very long-chain fatty acid catabolic process;GO:0043217//myelin maintenance;GO:0055085//transmembrane transport;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1990535//neuron projection maintenance;GO:2001280//positive regulation of unsaturated fatty acid biosynthetic process	--
ENSG00000173210	0.375	0.433	0.282	0.509	0.548	0.28	28	38	18	27	40	13	ABLIM3	actin binding LIM protein family member 3 [Source:HGNC Symbol;Acc:HGNC:29132]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07520	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	"GO:0006351//transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0030032//lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060271//cilium assembly;GO:1903955//positive regulation of protein targeting to mitochondrion"	--
ENSG00000173212	1.787	1.205	1.505	1.103	1.796	1.196	229.65	155.58	142.77	104.98	194.94	111.8	MAB21L3	mab-21 like 3 [Source:HGNC Symbol;Acc:HGNC:26787]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000173213	0.062	0.184	0.251	0.167	0.146	0.042	2	6	6	4	4	1	TUBB8B	tubulin beta 8B [Source:HGNC Symbol;Acc:HGNC:24983]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process	--
ENSG00000173214	2.342	2.457	1.986	2.602	1.839	2.377	291	297.48	189	222	176	240	MFSD4B	major facilitator superfamily domain containing 4B [Source:HGNC Symbol;Acc:HGNC:21053]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000173218	7.77	8.437	8.655	7.555	8.544	7.383	841	946	633	649	758	639	VANGL1	VANGL planar cell polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:15512]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04510	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane	GO:0005515//protein binding	"GO:0007275//multicellular organism development;GO:0043473//pigmentation;GO:0060071//Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000173221	4.23	3.501	3.421	1.048	2.041	3.034	85	69	46	15	34	43	GLRX	glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004362//glutathione-disulfide reductase (NADPH) activity;GO:0005515//protein binding;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0016740//transferase activity;GO:0047485//protein N-terminus binding;GO:0097573//glutathione oxidoreductase activity	GO:0015949//nucleobase-containing small molecule interconversion;GO:0045838//positive regulation of membrane potential;GO:0080058//protein deglutathionylation;GO:0098869//cellular oxidant detoxification;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000173226	4.52	4.61	3.449	4.123	3.308	3.279	226	231	121	136	140	120	IQCB1	IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0015630//microtubule cytoskeleton;GO:0032391//photoreceptor connecting cilium;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019899//enzyme binding	GO:0030030//cell projection organization;GO:0045494//photoreceptor cell maintenance;GO:0048496//maintenance of animal organ identity;GO:0060271//cilium assembly	--
ENSG00000173227	0.168	0.129	0	0	0.031	0	13	10	0	0	2	0	SYT12	synaptotagmin 12 [Source:HGNC Symbol;Acc:HGNC:18381]	-	-	-	-	GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0070382//exocytic vesicle;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098793//presynapse	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding	GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0046928//regulation of neurotransmitter secretion;GO:0048792//spontaneous exocytosis of neurotransmitter;GO:0060291//long-term synaptic potentiation;GO:0071277//cellular response to calcium ion	--
ENSG00000173230	4.656	2.788	2.766	2.765	2.753	2.275	923	564	316	276	504	361	GOLGB1	golgin B1 [Source:HGNC Symbol;Acc:HGNC:4429]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007030//Golgi organization;GO:0035988//chondrocyte proliferation;GO:1905793//protein localization to pericentriolar material"	--
ENSG00000173237	0	0	0	0	0	0	0	0	0	0	0	0	C11orf86	chromosome 11 open reading frame 86 [Source:HGNC Symbol;Acc:HGNC:34442]	-	-	-	-	-	-	-	--
ENSG00000173239	0	0	0	0	0	0	0	0	0	0	0	0	LIPM	lipase family member M [Source:HGNC Symbol;Acc:HGNC:23455]	-	-	-	-	GO:0005576//extracellular region	"GO:0004465//lipoprotein lipase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0070268//cornification	--
ENSG00000173250	0	0.031	0	0	0	0	0	2	0	0	0	0	GPR151	G protein-coupled receptor 151 [Source:HGNC Symbol;Acc:HGNC:23624]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002931//response to ischemia;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010447//response to acidic pH;GO:0050778//positive regulation of immune response	--
ENSG00000173253	0	0	0	0	0.117	0	0	0	0	0	4	0	DMRT2	doublesex and mab-3 related transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:2935]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007548//sex differentiation;GO:0008150//biological_process;GO:0014807//regulation of somitogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048706//embryonic skeletal system development;GO:2000287//positive regulation of myotome development"	DM
ENSG00000173258	1.222	1.177	0.793	0.796	2.546	0.935	297	258	170	129	246	183	ZNF483	zinc finger protein 483 [Source:HGNC Symbol;Acc:HGNC:23384]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000173261	0.075	0	0	0	0	0.035	3	0	0	0	0	1	PLAC8L1	PLAC8 like 1 [Source:HGNC Symbol;Acc:HGNC:31746]	-	-	-	-	-	-	-	--
ENSG00000173262	0	0	0.038	0	0	0	0	0	1	0	0	0	SLC2A14	solute carrier family 2 member 14 [Source:HGNC Symbol;Acc:HGNC:18301]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005355//glucose transmembrane transporter activity;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0007283//spermatogenesis;GO:0008643//carbohydrate transport;GO:0015749//monosaccharide transmembrane transport;GO:0030154//cell differentiation;GO:0046323//glucose import;GO:0055085//transmembrane transport;GO:0070837//dehydroascorbic acid transport;GO:1904659//glucose transmembrane transport	--
ENSG00000173264	26.78	31.534	27.78	36.254	32.03	34.774	847.16	911.01	629.02	770.13	861.04	763.1	GPR137	G protein-coupled receptor 137 [Source:HGNC Symbol;Acc:HGNC:24300]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0045671//negative regulation of osteoclast differentiation;GO:0045779//negative regulation of bone resorption;GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000173267	0	0.07	0	0	0.528	0.175	0	1	0	0	7	2	SNCG	synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:1903136//cuprous ion binding	GO:0007268//chemical synaptic transmission;GO:0008344//adult locomotory behavior;GO:0009306//protein secretion;GO:0014059//regulation of dopamine secretion;GO:0046928//regulation of neurotransmitter secretion;GO:0048488//synaptic vesicle endocytosis;GO:0050808//synapse organization;GO:1901214//regulation of neuron death	--
ENSG00000173269	0.035	0.035	0.016	0.146	0.111	0.161	3	3	1	2	8	10	MMRN2	multimerin 2 [Source:HGNC Symbol;Acc:HGNC:19888]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1990972//multimerin complex	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell population proliferation;GO:0030336//negative regulation of cell migration;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:1900426//positive regulation of defense response to bacterium;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1905278//positive regulation of epithelial tube formation;GO:1905332//positive regulation of morphogenesis of an epithelium	--
ENSG00000173272	41.345	42.127	40.787	49.792	42.772	41.499	515.17	526.93	375	459.41	449.69	377.07	MZT2A	mitotic spindle organizing protein 2A [Source:HGNC Symbol;Acc:HGNC:33187]	-	-	-	-	GO:0000931//gamma-tubulin large complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000173273	9.602	8.644	8.487	7.202	8.208	8.379	1802	1734	1251	992	1384	1095	TNKS	tankyrase [Source:HGNC Symbol;Acc:HGNC:11941]	-	-	-	-	"GO:0000139//Golgi membrane;GO:0000242//pericentriolar material;GO:0000781//chromosome, telomeric region;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031965//nuclear membrane;GO:0097431//mitotic spindle pole"	GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:1990404//protein ADP-ribosylase activity	"GO:0000209//protein polyubiquitination;GO:0006471//protein ADP-ribosylation;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032210//regulation of telomere maintenance via telomerase;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0051973//positive regulation of telomerase activity;GO:0070198//protein localization to chromosome, telomeric region;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904355//positive regulation of telomere capping;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904743//negative regulation of telomeric DNA binding;GO:1904908//negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric"	--
ENSG00000173275	2.551	2.121	2.198	1.703	1.973	1.942	201	176	130	101	133	113	ZNF449	zinc finger protein 449 [Source:HGNC Symbol;Acc:HGNC:21039]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007284//spermatogonial cell division	zf-C2H2
ENSG00000173276	2.744	1.864	2.158	1.805	2.153	1.916	340	248	202	174	233	183	ZBTB21	zinc finger and BTB domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13083]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0031208//POZ domain binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	ZBTB
ENSG00000173281	5.578	5.673	4.188	4.594	4.826	4.854	592	620	347	371	439	379	PPP1R3B	protein phosphatase 1 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:14942]	Organismal Systems;Human Diseases	Endocrine system;Endocrine and metabolic disease	ko04910//Insulin signaling pathway;ko04931//Insulin resistance	K07189;K07189	GO:0000164//protein phosphatase type 1 complex;GO:0042587//glycogen granule;GO:0043231//intracellular membrane-bounded organelle	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity;GO:0019899//enzyme binding;GO:0050196//[phosphorylase] phosphatase activity;GO:2001069//glycogen binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0005981//regulation of glycogen catabolic process;GO:0006470//protein dephosphorylation;GO:0050790//regulation of catalytic activity	--
ENSG00000173285	0	0	0	0	0	0	0	0	0	0	0	0	OR10K1	olfactory receptor family 10 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:14693]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000173302	0	0	0	0	0	0	0	0	0	0	0	0	GPR148	G protein-coupled receptor 148 [Source:HGNC Symbol;Acc:HGNC:23623]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000173320	4.3	3.421	3.738	3.338	3.747	2.681	572	465	346	299	384	311	STOX2	storkhead box 2 [Source:HGNC Symbol;Acc:HGNC:25450]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003674//molecular_function"	GO:0001893//maternal placenta development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009792//embryo development ending in birth or egg hatching;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000173327	31.97	36.352	37.818	39.242	42.327	36.39	2327	2607	1960	2091	2588	1907	MAP3K11	mitogen-activated protein kinase kinase kinase 11 [Source:HGNC Symbol;Acc:HGNC:6850]	Environmental Information Processing;Human Diseases	Signal transduction;Endocrine and metabolic disease	ko04010//MAPK signaling pathway;ko04932//Non-alcoholic fatty liver disease	K04419;K04419	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007017//microtubule-based process;GO:0007254//JNK cascade;GO:0008219//cell death;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0044843//cell cycle G1/S phase transition;GO:0046330//positive regulation of JNK cascade;GO:0046777//protein autophosphorylation	--
ENSG00000173334	10.349	10.085	11.659	18.524	16.346	15.908	682	728	591	866	890	746	TRIB1	tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004672//protein kinase activity;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0007254//JNK cascade;GO:0014912//negative regulation of smooth muscle cell migration;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032496//response to lipopolysaccharide;GO:0043405//regulation of MAP kinase activity;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045645//positive regulation of eosinophil differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045659//negative regulation of neutrophil differentiation;GO:0048662//negative regulation of smooth muscle cell proliferation	--
ENSG00000173335	0	0	0	0	0	0	0	0	0	0	0	0	CST9	cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019730//antimicrobial humoral response	--
ENSG00000173338	0.129	0.117	0.058	0.232	0.083	0	3	3	1	4	2	0	KCNK7	potassium two pore domain channel subfamily K member 7 [Source:HGNC Symbol;Acc:HGNC:6282]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000173349	0	0	0	0	0	0.407	0	0	0	0	0	22.99	SFT2D3	SFT2 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28767]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000173366	0	0	0	0	0	0	0	0	0	0	0	0	TLR9	"novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Cancer: overview;Infectious disease: parasitic	ko05168//Herpes simplex virus 1 infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05162//Measles;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05144//Malaria	K10161;K10161;K10161;K10161;K10161;K10161;K10161;K10161;K10161	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030016//myofibril;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0038187//pattern recognition receptor activity;GO:0051015//actin filament binding	GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010591//regulation of lamellipodium assembly;GO:0010976//positive regulation of neuron projection development;GO:0030042//actin filament depolymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0032755//positive regulation of interleukin-6 production;GO:0034162//toll-like receptor 9 signaling pathway;GO:0042989//sequestering of actin monomers;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0051016//barbed-end actin filament capping;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051171//regulation of nitrogen compound metabolic process;GO:0051607//defense response to virus;GO:0080090//regulation of primary metabolic process	--
ENSG00000173369	0	0	0	0	0.589	0	0	0	0	0	11	0	C1QB	complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03987;K03987;K03987;K03987;K03987;K03987;K03987;K03987	GO:0005576//extracellular region;GO:0045202//synapse;GO:0098794//postsynapse	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006958//complement activation, classical pathway;GO:0048839//inner ear development;GO:0098883//synapse pruning"	--
ENSG00000173372	0	0	0	0	0.161	0	0	0	0	0	3.08	0	C1QA	complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03986;K03986;K03986;K03986;K03986;K03986;K03986;K03986	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005602//complement component C1 complex;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0062167//complement component C1q complex;GO:0098794//postsynapse	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	"GO:0001774//microglial cell activation;GO:0002376//immune system process;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0007267//cell-cell signaling;GO:0007568//aging;GO:0016322//neuron remodeling;GO:0045087//innate immune response;GO:0048143//astrocyte activation;GO:0050808//synapse organization;GO:0098883//synapse pruning;GO:0150062//complement-mediated synapse pruning;GO:0150064//vertebrate eye-specific patterning;GO:1901216//positive regulation of neuron death"	--
ENSG00000173376	0.292	0.099	0.067	0.045	0.177	0.228	13	6	3	2	9	10	NDNF	neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding	GO:0001525//angiogenesis;GO:0001764//neuron migration;GO:0002931//response to ischemia;GO:0007263//nitric oxide mediated signal transduction;GO:0007399//nervous system development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010976//positive regulation of neuron projection development;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0021828//gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0030198//extracellular matrix organization;GO:0043524//negative regulation of neuron apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0061042//vascular wound healing;GO:0071456//cellular response to hypoxia;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000173389	0	0	0	0	0	0	0	0	0	0	0	0	IQCF1	IQ motif containing F1 [Source:HGNC Symbol;Acc:HGNC:28607]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0060474//positive regulation of flagellated sperm motility involved in capacitation;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000173391	0.103	0.22	0	0.106	0.186	0.153	1	6	0	4	8	2	OLR1	oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133]	Cellular Processes;Human Diseases;Organismal Systems	Transport and catabolism;Cardiovascular disease;Endocrine system	ko04145//Phagosome;ko05417//Lipid and atherosclerosis;ko03320//PPAR signaling pathway	K08763;K08763;K08763	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0070821//tertiary granule membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0008015//blood circulation;GO:0008219//cell death;GO:0042157//lipoprotein metabolic process	--
ENSG00000173401	0	0	0	0	0	0	0	0	0	0	0	0	GLIPR1L1	GLIPR1 like 1 [Source:HGNC Symbol;Acc:HGNC:28392]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft	-	GO:0007338//single fertilization	--
ENSG00000173402	61.409	65.964	68.412	62.981	65.785	68.537	6580	7294	5379	5136	6012	5353	DAG1	dystroglycan 1 [Source:HGNC Symbol;Acc:HGNC:2666]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06265;K06265;K06265;K06265;K06265	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016011//dystroglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0033268//node of Ranvier;GO:0034399//nuclear periphery;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0043231//intracellular membrane-bounded organelle;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0070938//contractile ring;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099524//postsynaptic cytosol	GO:0001618//virus receptor activity;GO:0002162//dystroglycan binding;GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0015631//tubulin binding;GO:0017166//vinculin binding;GO:0042169//SH2 domain binding;GO:0043236//laminin binding;GO:0043237//laminin-1 binding;GO:0051393//alpha-actinin binding	GO:0001954//positive regulation of cell-matrix adhesion;GO:0002009//morphogenesis of an epithelium;GO:0002011//morphogenesis of an epithelial sheet;GO:0006509//membrane protein ectodomain proteolysis;GO:0007411//axon guidance;GO:0007568//aging;GO:0010470//regulation of gastrulation;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0014037//Schwann cell differentiation;GO:0014044//Schwann cell development;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0016203//muscle attachment;GO:0016340//calcium-dependent cell-matrix adhesion;GO:0016476//regulation of embryonic cell shape;GO:0021675//nerve development;GO:0021682//nerve maturation;GO:0022011//myelination in peripheral nervous system;GO:0030336//negative regulation of cell migration;GO:0031103//axon regeneration;GO:0031643//positive regulation of myelination;GO:0034453//microtubule anchoring;GO:0043403//skeletal muscle tissue regeneration;GO:0043409//negative regulation of MAPK cascade;GO:0043434//response to peptide hormone;GO:0045860//positive regulation of protein kinase activity;GO:0046718//viral entry into host cell;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0050807//regulation of synapse organization;GO:0051898//negative regulation of protein kinase B signaling;GO:0060055//angiogenesis involved in wound healing;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0071260//cellular response to mechanical stimulus;GO:0071397//cellular response to cholesterol;GO:0071679//commissural neuron axon guidance;GO:0071711//basement membrane organization;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0098942//retrograde trans-synaptic signaling by trans-synaptic protein complex;GO:1904261//positive regulation of basement membrane assembly involved in embryonic body morphogenesis	--
ENSG00000173404	0	0.034	0	0	0.04	0	0	2	0	0	2	0	INSM1	INSM transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:6090]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0030332//cyclin binding;GO:0031490//chromatin DNA binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001933//negative regulation of protein phosphorylation;GO:0003309//type B pancreatic cell differentiation;GO:0003310//pancreatic A cell differentiation;GO:0003323//type B pancreatic cell development;GO:0003358//noradrenergic neuron development;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010564//regulation of cell cycle process;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0031018//endocrine pancreas development;GO:0035270//endocrine system development;GO:0042421//norepinephrine biosynthetic process;GO:0043254//regulation of protein-containing complex assembly;GO:0045597//positive regulation of cell differentiation;GO:0051726//regulation of cell cycle;GO:0060290//transdifferentiation;GO:0061104//adrenal chromaffin cell differentiation;GO:0061549//sympathetic ganglion development;GO:2000179//positive regulation of neural precursor cell proliferation	zf-C2H2
ENSG00000173406	1.297	1.314	0.739	0.963	0.596	1.006	68	97	37	47	54	56	DAB1	DAB adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:2661]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K20054	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0001764//neuron migration;GO:0007162//negative regulation of cell adhesion;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0007628//adult walking behavior;GO:0016358//dendrite development;GO:0021517//ventral spinal cord development;GO:0021589//cerebellum structural organization;GO:0021766//hippocampus development;GO:0021795//cerebral cortex cell migration;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021813//cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration;GO:0021942//radial glia guided migration of Purkinje cell;GO:0030154//cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0048712//negative regulation of astrocyte differentiation;GO:0050771//negative regulation of axonogenesis;GO:0051645//Golgi localization;GO:0097477//lateral motor column neuron migration	--
ENSG00000173409	12.627	11.242	13.023	13.367	12.289	16.235	367	327	280	286	300	330	ARV1	"ARV1 homolog, fatty acid homeostasis modulator [Source:HGNC Symbol;Acc:HGNC:29561]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032541//cortical endoplasmic reticulum	GO:0005515//protein binding;GO:0015248//sterol transporter activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008206//bile acid metabolic process;GO:0016125//sterol metabolic process;GO:0030301//cholesterol transport;GO:0032366//intracellular sterol transport;GO:0032383//regulation of intracellular cholesterol transport;GO:0090181//regulation of cholesterol metabolic process;GO:0097036//regulation of plasma membrane sterol distribution	--
ENSG00000173418	34.563	37.581	42.915	38.41	32.849	36.499	733	799	676	604	589	566	NAA20	"N-alpha-acetyltransferase 20, NatB catalytic subunit [Source:HGNC Symbol;Acc:HGNC:15908]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031416//NatB complex	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0017196//N-terminal peptidyl-methionine acetylation	--
ENSG00000173421	0	0	0.025	0	0	0	0	0	1	0	0	0	IHO1	interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0005694//chromosome	GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042138//meiotic DNA double-strand break formation;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0060629//regulation of homologous chromosome segregation	--
ENSG00000173431	0	0	0	0	0	0	0	0	0	0	0	0	RNASE8	ribonuclease A family member 8 [Source:HGNC Symbol;Acc:HGNC:19277]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004522//ribonuclease A activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity	"GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0061760//antifungal innate immune response;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000173432	0.244	0.185	0	1.256	0.859	0.384	3	2	0	10	8	3	SAA1	serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513]	-	-	-	-	GO:0005576//extracellular region;GO:0005881//cytoplasmic microtubule;GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen	GO:0001664//G protein-coupled receptor binding;GO:0008201//heparin binding	GO:0001819//positive regulation of cytokine production;GO:0006953//acute-phase response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0032732//positive regulation of interleukin-1 production;GO:0045785//positive regulation of cell adhesion;GO:0048246//macrophage chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050708//regulation of protein secretion;GO:0050728//negative regulation of inflammatory response	--
ENSG00000173436	7.633	7.539	8.657	8.714	6.119	7.887	352.83	340.9	350.8	326	282	291	MICOS10	mitochondrial contact site and cristae organizing system subunit 10 [Source:HGNC Symbol;Acc:HGNC:32068]	-	-	-	-	GO:0001401//SAM complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0008150//biological_process;GO:0042407//cristae formation	--
ENSG00000173442	19.232	18.601	21.996	24.313	22.152	25.347	1319	1345	1088	1257	1362	1233	EHBP1L1	EH domain binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:30682]	-	-	-	-	GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0016020//membrane;GO:0031941//filamentous actin	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0030036//actin cytoskeleton organization	--
ENSG00000173451	4.75	2.819	3.135	2.126	2.148	4.021	337	230	153	126	155	171	THAP2	THAP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20854]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0046872//metal ion binding	-	THAP
ENSG00000173452	0	0	0	0	0	0	0	0	0	0	0	0	TMEM196	transmembrane protein 196 [Source:HGNC Symbol;Acc:HGNC:22431]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000173456	16.163	18.114	19.093	20.885	21.202	20.381	933	1051	814	893	1034	856	RNF26	ring finger protein 26 [Source:HGNC Symbol;Acc:HGNC:14646]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007032//endosome organization;GO:0016567//protein ubiquitination;GO:0032479//regulation of type I interferon production;GO:0050687//negative regulation of defense response to virus;GO:0070979//protein K11-linked ubiquitination;GO:1905719//protein localization to perinuclear region of cytoplasm	--
ENSG00000173457	33.685	37.683	36.896	43.303	39.928	36.045	691	777	559	658	692	538	PPP1R14B	protein phosphatase 1 regulatory inhibitor subunit 14B [Source:HGNC Symbol;Acc:HGNC:9057]	-	-	-	-	GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity	GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response	--
ENSG00000173464	0	0	0	0	0	0	0	0	0	0	0	0	RNASE11	ribonuclease A family member 11 (inactive) [Source:HGNC Symbol;Acc:HGNC:19269]	-	-	-	-	GO:0005576//extracellular region	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000173465	9.609	9.574	11.114	8.488	9.559	8.712	154.43	155	132	102	131	102	ZNRD2	zinc ribbon domain containing 2 [Source:HGNC Symbol;Acc:HGNC:11328]	-	-	-	-	-	GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000173467	0	0	0	0	0.364	0	0	0	0	0	3	0	AGR3	"anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle	GO:0002162//dystroglycan binding;GO:0005515//protein binding	GO:0008150//biological_process;GO:0060548//negative regulation of cell death	--
ENSG00000173473	39	35.63	33.193	27.247	29.395	28.271	5140	4720	3231	2660	3273	2711	SMARCC1	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104]"	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K11649;K11649	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex;GO:0032991//protein-containing complex;GO:0035060//brahma complex;GO:0071564//npBAF complex;GO:0071565//nBAF complex;GO:0140288//GBAF complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0042393//histone binding;GO:0047485//protein N-terminus binding	"GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045582//positive regulation of T cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:1902459//positive regulation of stem cell population maintenance;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	MYB
ENSG00000173480	5.152	5.244	3.446	3.36	3.605	3.953	347.33	366.75	203.09	186.23	225.33	196.68	ZNF417	zinc finger protein 417 [Source:HGNC Symbol;Acc:HGNC:20646]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000173482	14.108	13.923	16.708	12.739	14.67	15.579	1532	1524	1273	1031	1408	1278	PTPRM	protein tyrosine phosphatase receptor type M [Source:HGNC Symbol;Acc:HGNC:9675]	Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Cellular community - eukaryotes	ko04514//Cell adhesion molecules;ko04520//Adherens junction	K05693;K05693	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding	GO:0001937//negative regulation of endothelial cell proliferation;GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0009410//response to xenobiotic stimulus;GO:0010596//negative regulation of endothelial cell migration;GO:0010842//retina layer formation;GO:0016311//dephosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0031175//neuron projection development;GO:0031290//retinal ganglion cell axon guidance;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000173486	46.916	50.912	57.468	60.141	55.932	66.444	562.32	614.34	508.32	532.88	567.75	579.66	FKBP2	FKBP prolyl isomerase 2 [Source:HGNC Symbol;Acc:HGNC:3718]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005528//FK506 binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding	--
ENSG00000173511	67.132	69.734	71.311	93.443	80.794	72.368	2496	2599	1956	2570	2535	1956	VEGFB	vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cellular community - eukaryotes;Endocrine system;Endocrine and metabolic disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04510//Focal adhesion;ko04926//Relaxin signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications	K16858;K16858;K16858;K16858;K16858;K16858;K16858;K16858;K16858	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen	GO:0005172//vascular endothelial growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0043183//vascular endothelial growth factor receptor 1 binding;GO:0048018//receptor ligand activity	GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0006493//protein O-linked glycosylation;GO:0007165//signal transduction;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0035470//positive regulation of vascular wound healing;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:0060048//cardiac muscle contraction;GO:0060754//positive regulation of mast cell chemotaxis;GO:0060976//coronary vasculature development;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000173517	12.502	9.665	7.96	7.619	7.377	7.092	2593	2164	1333	1247	1485	1197	PEAK1	pseudopodium enriched atypical kinase 1 [Source:HGNC Symbol;Acc:HGNC:29431]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030054//cell junction	GO:0004672//protein kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0046777//protein autophosphorylation;GO:0048041//focal adhesion assembly;GO:0051893//regulation of focal adhesion assembly	--
ENSG00000173530	2.032	2.008	2.087	1.823	1.986	2.943	149	148	113	99	123	157	TNFRSF10D	TNF receptor superfamily member 10d [Source:HGNC Symbol;Acc:HGNC:11907]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22702;K22702	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0045569//TRAIL binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process	--
ENSG00000173531	1.521	2.271	3.337	3.188	4.218	3.508	96	131	115	149	160	159	MST1	macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K23441	GO:0005737//cytoplasm;GO:0005773//vacuole	GO:0004252//serine-type endopeptidase activity;GO:0019899//enzyme binding;GO:0030971//receptor tyrosine kinase binding	GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0007566//embryo implantation;GO:0010628//positive regulation of gene expression;GO:0010758//regulation of macrophage chemotaxis;GO:0030317//flagellated sperm motility;GO:0030879//mammary gland development;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0060763//mammary duct terminal end bud growth;GO:0071456//cellular response to hypoxia;GO:1904036//negative regulation of epithelial cell apoptotic process	--
ENSG00000173535	0	0	0	0.047	0	0	0	0	0	1	0	0	TNFRSF10C	TNF receptor superfamily member 10c [Source:HGNC Symbol;Acc:HGNC:11906]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04061//Viral protein interaction with cytokine and cytokine receptor	K22701;K22701	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0045569//TRAIL binding	GO:0006915//apoptotic process;GO:0036462//TRAIL-activated apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process	--
ENSG00000173540	8.664	10.518	11.853	9.334	8.266	9.365	570.49	685.45	507.2	426.42	424.45	429.38	GMPPB	GDP-mannose pyrophosphorylase B [Source:HGNC Symbol;Acc:HGNC:22932]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K00966;K00966;K00966	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004475//mannose-1-phosphate guanylyltransferase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006486//protein glycosylation;GO:0009058//biosynthetic process;GO:0009298//GDP-mannose biosynthetic process	--
ENSG00000173542	4.012	2.533	2.328	2.161	1.836	2.976	493	323	221	202	208	209	MOB1B	MOB kinase activator 1B [Source:HGNC Symbol;Acc:HGNC:29801]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K06685;K06685	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019209//kinase activator activity;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0031952//regulation of protein autophosphorylation;GO:0032147//activation of protein kinase activity;GO:0033674//positive regulation of kinase activity;GO:0035329//hippo signaling	--
ENSG00000173545	12.794	15.314	11.969	14.87	13.773	14.518	453	545	313	390	412	374	ZNF622	zinc finger protein 622 [Source:HGNC Symbol;Acc:HGNC:30958]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030687//preribosome, large subunit precursor"	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0033674//positive regulation of kinase activity;GO:0042273//ribosomal large subunit biogenesis;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0046330//positive regulation of JNK cascade	zf-C2H2
ENSG00000173546	1.623	1.504	1.008	0.557	0.578	0.504	279	260	128	71	84	63	CSPG4	chondroitin sulfate proteoglycan 4 [Source:HGNC Symbol;Acc:HGNC:2466]	-	-	-	-	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031258//lamellipodium membrane;GO:0042995//cell projection;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0015026//coreceptor activity;GO:0019901//protein kinase binding	GO:0001525//angiogenesis;GO:0006929//substrate-dependent cell migration;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell population proliferation;GO:0008347//glial cell migration;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048771//tissue remodeling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0097178//ruffle assembly	--
ENSG00000173548	13.669	14.053	14.822	13.306	15.333	15.508	1581.81	1784.49	1205.33	1254.66	1485.39	1299.68	SNX33	sorting nexin 33 [Source:HGNC Symbol;Acc:HGNC:28468]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K17923	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding	GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0007049//cell cycle;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0017038//protein import;GO:0036089//cleavage furrow formation;GO:0044351//macropinocytosis;GO:0045806//negative regulation of endocytosis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051301//cell division;GO:0097320//plasma membrane tubulation;GO:2000009//negative regulation of protein localization to cell surface;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000173557	0	0	0.182	0.272	0.477	0	0	0	2	3	6	0	FAM166C	family with sequence similarity 166 member C [Source:HGNC Symbol;Acc:HGNC:27938]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000173559	1.386	2.053	2.052	2.251	2.284	3.85	77.05	101	77	92.01	106.04	138.06	NABP1	nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035861//site of double-strand break;GO:0070876//SOSS complex"	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0044818//mitotic G2/M transition checkpoint	--
ENSG00000173567	0.083	0.055	0.075	0.1	0.049	0.03	6	4	4	5	3	2	ADGRF3	adhesion G protein-coupled receptor F3 [Source:HGNC Symbol;Acc:HGNC:18989]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000173572	0	0	0	0	0	0	0	0	0	0	0	0	NLRP13	NLR family pyrin domain containing 13 [Source:HGNC Symbol;Acc:HGNC:22937]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000173575	17.305	17.617	10.911	9.31	11.106	11.399	1780.03	1510.18	1065.2	767.68	1089.72	904	CHD2	chromodomain helicase DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1917]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0007517//muscle organ development;GO:0032508//DNA duplex unwinding	--
ENSG00000173578	0	0.01	0	0	0	0	0	1	0	0	0	0	XCR1	X-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1625]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04193;K04193;K04193	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	"GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0034097//response to cytokine;GO:0051209//release of sequestered calcium ion into cytosol;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway"	--
ENSG00000173581	15.272	16.852	16.33	18.746	19.327	19.138	560	586	442	494	567	456	CCDC106	coiled-coil domain containing 106 [Source:HGNC Symbol;Acc:HGNC:30181]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000173585	0.267	0.337	0.157	0.285	0.162	0.176	14	16	4	11	7	6	CCR9	C-C motif chemokine receptor 9 [Source:HGNC Symbol;Acc:HGNC:1610]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04672//Intestinal immune network for IgA production;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04184;K04184;K04184;K04184	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	"GO:0002305//CD8-positive, gamma-delta intraepithelial T cell differentiation;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway"	--
ENSG00000173588	1.731	1.244	1.219	0.982	1.384	1.101	100	59	33	43	52	51	CEP83	centrosomal protein 83 [Source:HGNC Symbol;Acc:HGNC:17966]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0097539//ciliary transition fiber	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0048278//vesicle docking;GO:0051660//establishment of centrosome localization;GO:0060271//cilium assembly;GO:0071539//protein localization to centrosome	--
ENSG00000173597	0.253	0.308	0.158	0.288	0.574	0.142	36.79	45.08	17.02	8.8	30	15.01	SULT1B1	sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0006068//ethanol catabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0009812//flavonoid metabolic process;GO:0018958//phenol-containing compound metabolic process;GO:0030855//epithelial cell differentiation;GO:0042403//thyroid hormone metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000173598	22.335	21.048	17.518	17.551	18.272	16.306	1816.72	1698.61	1035.28	986.59	1194.41	949.74	NUDT4	nudix hydrolase 4 [Source:HGNC Symbol;Acc:HGNC:8051]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000298//endopolyphosphatase activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0030515//snoRNA binding;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity	GO:0019722//calcium-mediated signaling;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0035556//intracellular signal transduction;GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	--
ENSG00000173599	6.717	7.271	7.592	8.389	8.103	8.472	549	600	461	508	571	497	PC	pyruvate carboxylase [Source:HGNC Symbol;Acc:HGNC:8636]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00620//Pyruvate metabolism;ko00020//Citrate cycle (TCA cycle)	K01958;K01958;K01958;K01958;K01958	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004736//pyruvate carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006090//pyruvate metabolic process;GO:0006094//gluconeogenesis;GO:0006629//lipid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0008152//metabolic process;GO:0010629//negative regulation of gene expression;GO:0019074//viral RNA genome packaging;GO:0019076//viral release from host cell;GO:0034641//cellular nitrogen compound metabolic process;GO:0043603//cellular amide metabolic process;GO:0044281//small molecule metabolic process;GO:0044794//positive regulation by host of viral process	--
ENSG00000173610	0	0.019	0	0	0.045	0.028	0	1	0	0	2	1	UGT2A1	UDP glucuronosyltransferase family 2 member A1 complex locus [Source:HGNC Symbol;Acc:HGNC:12542]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell;GO:0008206//bile acid metabolic process;GO:0050896//response to stimulus;GO:0052695//cellular glucuronidation	--
ENSG00000173611	6.151	6.018	5.55	3.233	4.424	3.243	1186	988	655	412	641	528	SCAI	suppressor of cancer cell invasion [Source:HGNC Symbol;Acc:HGNC:26709]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated;GO:0009968//negative regulation of signal transduction;GO:0030336//negative regulation of cell migration;GO:0035024//negative regulation of Rho protein signal transduction;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000173612	0	0	0	0.056	0	0.068	0	0	0	2	0	3	GPRC6A	G protein-coupled receptor class C group 6 member A [Source:HGNC Symbol;Acc:HGNC:18510]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K04622	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0043200//response to amino acid	--
ENSG00000173614	5.397	5.818	6.424	5.46	5.492	7.293	276	326	253	232	246	260	NMNAT1	nicotinamide nucleotide adenylyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17877]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K06210;K06210	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0003824//catalytic activity;GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042802//identical protein binding	GO:0009058//biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0009435//NAD biosynthetic process;GO:0009611//response to wounding;GO:0019363//pyridine nucleotide biosynthetic process;GO:1901215//negative regulation of neuron death;GO:1990966//ATP generation from poly-ADP-D-ribose	--
ENSG00000173621	4.061	4.4	3.862	4.386	4.435	3.699	223	241	158	179	223	147	LRFN4	leucine rich repeat and fibronectin type III domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28456]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0099151//regulation of postsynaptic density assembly;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000173626	0.049	0	0	0	0	0	1	0	0	0	0	0	TRAPPC3L	trafficking protein particle complex subunit 3L [Source:HGNC Symbol;Acc:HGNC:21090]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0033106//cis-Golgi network membrane	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0008150//biological_process;GO:0016192//vesicle-mediated transport;GO:0048193//Golgi vesicle transport	--
ENSG00000173627	0	0.121	0.117	0	0	0.024	0	7	5	0	0	1	APOBEC4	apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 [Source:HGNC Symbol;Acc:HGNC:32152]	-	-	-	-	-	"GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046872//metal ion binding"	GO:0006397//mRNA processing	--
ENSG00000173638	43.088	43.912	51.81	60.934	56.764	58.059	2120.27	2104.14	1887.56	2189.09	2347.54	2163.64	SLC19A1	solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937]	Human Diseases;Organismal Systems	Drug resistance: antineoplastic;Digestive system	ko01523//Antifolate resistance;ko04977//Vitamin digestion and absorption	K14609;K14609	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane	"GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0008514//organic anion transmembrane transporter activity;GO:0008517//folic acid transmembrane transporter activity;GO:0008518//folate:anion antiporter activity;GO:0015297//antiporter activity;GO:0015350//methotrexate transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity;GO:0061507//2',3'-cyclic GMP-AMP binding;GO:0090482//vitamin transmembrane transporter activity;GO:0140360//cyclic-GMP-AMP transmembrane transporter activity"	GO:0006855//xenobiotic transmembrane transport;GO:0007565//female pregnancy;GO:0015711//organic anion transport;GO:0015884//folic acid transport;GO:0035461//vitamin transmembrane transport;GO:0046655//folic acid metabolic process;GO:0051180//vitamin transport;GO:0051958//methotrexate transport;GO:0055085//transmembrane transport;GO:0098838//folate transmembrane transport;GO:0140361//cyclic-GMP-AMP transmembrane import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1904447//folate import across plasma membrane	--
ENSG00000173641	28.705	27.297	22.89	33.433	34.976	33.745	1078	1064	606	978	1134	900	HSPB7	heat shock protein family B (small) member 7 [Source:HGNC Symbol;Acc:HGNC:5249]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0015629//actin cytoskeleton;GO:0016235//aggresome	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0031005//filamin binding	GO:0006986//response to unfolded protein;GO:0007507//heart development;GO:0008016//regulation of heart contraction	--
ENSG00000173653	3.155	3.168	3.687	4.407	3.728	4.165	94	95	80	99	94	91	RCE1	Ras converting CAAX endopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:13721]	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K08658	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0110165//cellular anatomical entity	GO:0004175//endopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008238//exopeptidase activity;GO:0016787//hydrolase activity	GO:0000165//MAPK cascade;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0018342//protein prenylation;GO:0071586//CAAX-box protein processing;GO:0080120//CAAX-box protein maturation	--
ENSG00000173660	90.28	87.134	94.139	109.241	90.216	107.986	1042.99	1005.99	803	924.99	876	905.99	UQCRH	ubiquinol-cytochrome c reductase hinge protein [Source:HGNC Symbol;Acc:HGNC:12590]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008121//ubiquinol-cytochrome-c reductase activity	"GO:0006119//oxidative phosphorylation;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0009060//aerobic respiration;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000173662	0	0	0	0	0	0	0	0	0	0	0	0	TAS1R1	taste 1 receptor member 1 [Source:HGNC Symbol;Acc:HGNC:14448]	Organismal Systems	Sensory system	ko04742//Taste transduction	K04624	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0050917//sensory perception of umami taste	--
ENSG00000173673	0	0	0	0	0	0	0	0	0	0	0	0	HES3	hes family bHLH transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:26226]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K09088	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0071820//N-box binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0045665//negative regulation of neuron differentiation;GO:0050767//regulation of neurogenesis	bHLH
ENSG00000173674	23.281	22.872	17.813	15.489	16.906	17.63	1880	1579	1105	1009	1175	1088	EIF1AX	eukaryotic translation initiation factor 1A X-linked [Source:HGNC Symbol;Acc:HGNC:3250]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding"	GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000173678	0.109	0.02	0.165	0.055	0	0.142	5.51	1.02	5	2.06	0	5.23	SPDYE2B	speedy/RINGO cell cycle regulator family member E2B [Source:HGNC Symbol;Acc:HGNC:48334]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000173679	0	0	0	0	0	0	0	0	0	0	0	0	OR1L1	olfactory receptor family 1 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:8213]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000173681	1.612	1.375	1.1	1.108	1.03	1.134	217	193	95	114	121	112	BCLAF3	BCLAF1 and THRAP3 family member 3 [Source:HGNC Symbol;Acc:HGNC:27413]	-	-	-	-	GO:0005739//mitochondrion;GO:0016592//mediator complex	GO:0003677//DNA binding;GO:0003712//transcription coregulator activity	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000173692	33.781	30.24	31.484	26.391	27.421	28.993	2324	2096	1551	1350	1592	1456	PSMD1	"proteasome 26S subunit, non-ATPase 1 [Source:HGNC Symbol;Acc:HGNC:9554]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03032;K03032;K03032;K03032;K03032;K03032;K03032;K03032;K03032	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034515//proteasome storage granule;GO:0035578//azurophil granule lumen"	GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0031625//ubiquitin protein ligase binding	GO:0042176//regulation of protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000173698	1.286	1.082	0.854	1.049	1.395	1.062	126	106	62	72	115	75	ADGRG2	adhesion G protein-coupled receptor G2 [Source:HGNC Symbol;Acc:HGNC:4516]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis	--
ENSG00000173699	0	0	0	0	0	0	0	0	0	0	0	0	SPATA3	spermatogenesis associated 3 [Source:HGNC Symbol;Acc:HGNC:17884]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	-	--
ENSG00000173702	0	0	0	0.111	0	0	0	0	0	1	0	0	MUC13	"mucin 13, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7511]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0071944//cell periphery	GO:0042803//protein homodimerization activity	GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000173705	3.887	3.221	3.887	2.474	2.494	2.246	371	309	274	164	191	156	SUSD5	sushi domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29061]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005540//hyaluronic acid binding	GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway	--
ENSG00000173706	27.263	31.651	31.22	28.118	30.178	23.113	3317	3726	2431	2423	2893	2236	HEG1	heart development protein with EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:29227]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001885//endothelial cell development;GO:0001886//endothelial cell morphogenesis;GO:0001944//vasculature development;GO:0001945//lymph vessel development;GO:0003017//lymph circulation;GO:0003209//cardiac atrium morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003281//ventricular septum development;GO:0007043//cell-cell junction assembly;GO:0007507//heart development;GO:0009791//post-embryonic development;GO:0030324//lung development;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035264//multicellular organism growth;GO:0045216//cell-cell junction organization;GO:0048845//venous blood vessel morphogenesis;GO:0050878//regulation of body fluid levels;GO:0055017//cardiac muscle tissue growth;GO:0060039//pericardium development;GO:0090271//positive regulation of fibroblast growth factor production;GO:1902414//protein localization to cell junction;GO:1905709//negative regulation of membrane permeability;GO:2000299//negative regulation of Rho-dependent protein serine/threonine kinase activity	--
ENSG00000173714	76.684	86.188	61.151	35.753	47.83	26.023	5435	6140	3201	1877	2864	1342	WFIKKN2	"WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004857//enzyme inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0048019//receptor antagonist activity;GO:0050431//transforming growth factor beta binding	GO:0001501//skeletal system development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0043392//negative regulation of DNA binding;GO:0055001//muscle cell development;GO:0060021//roof of mouth development;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000173715	8.13	7.891	8.654	10.581	7.965	6.777	265	277	245	272	228	199	C11orf80	chromosome 11 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:26197]	-	-	-	-	GO:0005694//chromosome	-	GO:0007131//reciprocal meiotic recombination;GO:0042138//meiotic DNA double-strand break formation;GO:0051321//meiotic cell cycle	--
ENSG00000173726	72.956	66.14	67.285	70.617	66.92	69.389	4968	4527	3384	3562	3850	3438	TOMM20	translocase of outer mitochondrial membrane 20 [Source:HGNC Symbol;Acc:HGNC:20947]	-	-	-	-	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0097225//sperm midpiece	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0015450//protein-transporting ATPase activity;GO:0030943//mitochondrion targeting sequence binding;GO:0051082//unfolded protein binding	"GO:0006605//protein targeting;GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0014850//response to muscle activity;GO:0015031//protein transport;GO:0016031//tRNA import into mitochondrion;GO:0030150//protein import into mitochondrial matrix;GO:0045040//protein insertion into mitochondrial outer membrane;GO:1905242//response to 3,3',5-triiodo-L-thyronine"	--
ENSG00000173728	0	0	0	0	0	0	0	0	0	0	0	0	C1orf100	chromosome 1 open reading frame 100 [Source:HGNC Symbol;Acc:HGNC:30435]	-	-	-	-	-	-	-	--
ENSG00000173744	18.903	19.735	20.082	19.147	18.958	23.446	1305	1204	866	816	903	976	AGFG1	ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006406//mRNA export from nucleus;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0050790//regulation of catalytic activity;GO:0051028//mRNA transport	--
ENSG00000173757	5.79	5.632	5.739	5.828	6.282	6.542	609.94	589.75	446.57	454.76	559.11	501.43	STAT5B	signal transducer and activator of transcription 5B [Source:HGNC Symbol;Acc:HGNC:11367]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: overview;Immune system;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Endocrine system;Immune system;Endocrine and metabolic disease;Immune system;Signal transduction;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05162//Measles;ko04935//Growth hormone synthesis, secretion and action;ko04659//Th17 cell differentiation;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04658//Th1 and Th2 cell differentiation;ko04012//ErbB signaling pathway;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia"	K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224;K11224	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035259//glucocorticoid receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity"	"GO:0001553//luteinization;GO:0001779//natural killer cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006952//defense response;GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0007548//sex differentiation;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0019218//regulation of steroid metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0019530//taurine metabolic process;GO:0019915//lipid storage;GO:0030155//regulation of cell adhesion;GO:0030856//regulation of epithelial cell differentiation;GO:0032355//response to estradiol;GO:0032743//positive regulation of interleukin-2 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0032870//cellular response to hormone stimulus;GO:0033077//T cell differentiation in thymus;GO:0040014//regulation of multicellular organism growth;GO:0040018//positive regulation of multicellular organism growth;GO:0042104//positive regulation of activated T cell proliferation;GO:0042127//regulation of cell population proliferation;GO:0042448//progesterone metabolic process;GO:0043029//T cell homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0043434//response to peptide hormone;GO:0045579//positive regulation of B cell differentiation;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045621//positive regulation of lymphocyte differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046543//development of secondary female sexual characteristics;GO:0046544//development of secondary male sexual characteristics;GO:0048541//Peyer's patch development;GO:0050729//positive regulation of inflammatory response;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0070669//response to interleukin-2;GO:0070670//response to interleukin-4;GO:0070672//response to interleukin-15;GO:0071363//cellular response to growth factor stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0097531//mast cell migration"	STAT
ENSG00000173762	0.113	0	0	0	0.089	0.072	3	0	0	0	2	1	CD7	CD7 molecule [Source:HGNC Symbol;Acc:HGNC:1695]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06457	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042110//T cell activation	--
ENSG00000173769	0	0	0	0	0	0	0	0	0	0	0	0	TOPAZ1	testis and ovary specific TOPAZ 1 [Source:HGNC Symbol;Acc:HGNC:24746]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0030154//cell differentiation;GO:0048137//spermatocyte division;GO:0098781//ncRNA transcription;GO:1901995//positive regulation of meiotic cell cycle phase transition	--
ENSG00000173786	50.483	52.017	54.782	61.899	55.392	53.355	2813.34	3017.67	2281.34	2602.81	2687.93	2187	CNP	"2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158]"	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0031143//pseudopodium;GO:0035748//myelin sheath abaxonal region;GO:0035749//myelin sheath adaxonal region;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043209//myelin sheath;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0004113//2',3'-cyclic-nucleotide 3'-phosphodiesterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030551//cyclic nucleotide binding"	GO:0000226//microtubule cytoskeleton organization;GO:0007268//chemical synaptic transmission;GO:0007409//axonogenesis;GO:0007568//aging;GO:0008344//adult locomotory behavior;GO:0009214//cyclic nucleotide catabolic process;GO:0009636//response to toxic substance;GO:0021762//substantia nigra development;GO:0030900//forebrain development;GO:0032496//response to lipopolysaccharide;GO:0046902//regulation of mitochondrial membrane permeability;GO:0048709//oligodendrocyte differentiation	--
ENSG00000173801	33.447	31.393	33.226	41.284	44.778	38.016	2078	2031	1532	1898	2368	1730	JUP	junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05226//Gastric cancer;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko05221//Acute myeloid leukemia	K10056;K10056;K10056;K10056;K10056	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0005916//fascia adherens;GO:0005925//focal adhesion;GO:0009898//cytoplasmic side of plasma membrane;GO:0014704//intercalated disc;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0016342//catenin complex;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030057//desmosome;GO:0032993//protein-DNA complex;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:0071665//gamma-catenin-TCF7L2 complex;GO:1904813//ficolin-1-rich granule lumen	GO:0003713//transcription coactivator activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication;GO:0106006//cytoskeletal protein-membrane anchor activity	GO:0001954//positive regulation of cell-matrix adhesion;GO:0002159//desmosome assembly;GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0042127//regulation of cell population proliferation;GO:0042307//positive regulation of protein import into nucleus;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0043588//skin development;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050982//detection of mechanical stimulus;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0071603//endothelial cell-cell adhesion;GO:0071681//cellular response to indole-3-methanol;GO:0072659//protein localization to plasma membrane;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential	--
ENSG00000173805	0	0.025	0	0	0.058	0.172	0	2	0	0	4	4	HAP1	huntingtin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:4812]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04727//GABAergic synapse	K04647;K04647;K04647;K04647	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0015629//actin cytoskeleton;GO:0016234//inclusion body;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0098793//presynapse;GO:1904115//axon cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0044325//transmembrane transporter binding;GO:0048403//brain-derived neurotrophic factor binding	"GO:0006605//protein targeting;GO:0006887//exocytosis;GO:0006914//autophagy;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0008089//anterograde axonal transport;GO:0008090//retrograde axonal transport;GO:0008104//protein localization;GO:0015031//protein transport;GO:0017157//regulation of exocytosis;GO:0021549//cerebellum development;GO:0021979//hypothalamus cell differentiation;GO:0022008//neurogenesis;GO:0030030//cell projection organization;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032901//positive regulation of neurotrophin production;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0047496//vesicle transport along microtubule;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048311//mitochondrion distribution;GO:0050769//positive regulation of neurogenesis;GO:0098957//anterograde axonal transport of mitochondrion;GO:1902430//negative regulation of amyloid-beta formation;GO:1902513//regulation of organelle transport along microtubule;GO:1902857//positive regulation of non-motile cilium assembly"	--
ENSG00000173809	0.015	0.037	0.062	0.022	0	0.042	1	4	3	2	0	2	TDRD12	tudor domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25044]	-	-	-	-	GO:0005575//cellular_component;GO:1990923//PET complex	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle	--
ENSG00000173812	133.418	133.321	134.79	156.913	134.57	160.209	3824	3839	2955	3467	3341	3548	EIF1	eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016282//eukaryotic 43S preinitiation complex	"GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0043024//ribosomal small subunit binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation	--
ENSG00000173818	3.566	5.311	5.056	4.563	3.044	6.662	139	169	117	101	91	116	ENDOV	endonuclease V [Source:HGNC Symbol;Acc:HGNC:26640]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	"GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046872//metal ion binding"	"GO:0006281//DNA repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000173821	9.066	8.922	9.51	6.994	9	8.19	2843	2837	2242.21	1697	2374	1805	RNF213	ring finger protein 213 [Source:HGNC Symbol;Acc:HGNC:14539]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0016020//membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001525//angiogenesis;GO:0002040//sprouting angiogenesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0019216//regulation of lipid metabolic process;GO:0042742//defense response to bacterium;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0098792//xenophagy;GO:0120323//lipid ubiquitination;GO:0140042//lipid droplet formation;GO:2000051//negative regulation of non-canonical Wnt signaling pathway	--
ENSG00000173825	0.024	0.071	0.161	0.289	0.113	0.229	1	3	5	9	4	7	TIGD3	tigger transposable element derived 3 [Source:HGNC Symbol;Acc:HGNC:18334]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000173826	0	0	0	0.022	0	0	0	0	0	1	0	0	KCNH6	potassium voltage-gated channel subfamily H member 6 [Source:HGNC Symbol;Acc:HGNC:18862]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086011//membrane repolarization during action potential;GO:0086091//regulation of heart rate by cardiac conduction	--
ENSG00000173838	0.061	0.081	0.155	0.055	0.019	0.112	3	4	3	2	1	4	MARCHF10	membrane associated ring-CH-type finger 10 [Source:HGNC Symbol;Acc:HGNC:26655]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000173846	1.669	1.353	1.2	1.53	1.536	0.623	81	66	43	55	63	22	PLK3	polo like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2154]	Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Signal transduction;Immune system	ko05152//Tuberculosis;ko04068//FoxO signaling pathway;ko04625//C-type lectin receptor signaling pathway	K08862;K08862;K08862	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0000166//nucleotide binding;GO:0002039//p53 binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0000302//response to reactive oxygen species;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006970//response to osmotic stress;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007049//cell cycle;GO:0007113//endomitotic cell cycle;GO:0009314//response to radiation;GO:0016310//phosphorylation;GO:0031122//cytoplasmic microtubule organization;GO:0032465//regulation of cytokinesis;GO:0043066//negative regulation of apoptotic process;GO:0043491//protein kinase B signaling;GO:0044819//mitotic G1/S transition checkpoint signaling;GO:0051302//regulation of cell division;GO:0090166//Golgi disassembly;GO:0090316//positive regulation of intracellular protein transport;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904716//positive regulation of chaperone-mediated autophagy;GO:2000777//positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia"	--
ENSG00000173848	13.91	12.589	13.201	10.8	10.37	10.581	961	882	671	546	609	529	NET1	neuroepithelial cell transforming 1 [Source:HGNC Symbol;Acc:HGNC:14592]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0001558//regulation of cell growth;GO:0007165//signal transduction;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051451//myoblast migration;GO:0070301//cellular response to hydrogen peroxide;GO:0071479//cellular response to ionizing radiation	--
ENSG00000173852	14.262	14.605	14.709	9.038	10.142	11.853	1498	1541	1088	701	897	896	DPY19L1	dpy-19 like C-mannosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:22205]	-	-	-	-	GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	--
ENSG00000173867	0.065	0.351	0.173	0	0.296	0.411	4.39	23.92	8.67	0	16.96	20.27	DET1	novel transcript	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10571	-	-	-	--
ENSG00000173868	0	0	0.032	0.164	0	0.153	0	0	1	4	0	2	PHOSPHO1	phosphoethanolamine/phosphocholine phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:16815]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K06124;K06124	GO:0005829//cytosol;GO:0031012//extracellular matrix;GO:0065010//extracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0052731//phosphocholine phosphatase activity;GO:0052732//phosphoethanolamine phosphatase activity	GO:0001958//endochondral ossification;GO:0016311//dephosphorylation;GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0035630//bone mineralization involved in bone maturation	--
ENSG00000173875	7.165	4.668	3.302	2.874	4.11	3.531	553	459	327	268	341	274	ZNF791	zinc finger protein 791 [Source:HGNC Symbol;Acc:HGNC:26895]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000173889	6.783	4.292	5.059	4.013	5.895	5.003	1143	845	603	484	728	636	PHC3	polyhomeotic homolog 3 [Source:HGNC Symbol;Acc:HGNC:15682]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000173890	0.375	0.091	0.133	0	0.261	0.091	7	3	4	0	4	1	GPR160	G protein-coupled receptor 160 [Source:HGNC Symbol;Acc:HGNC:23693]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000173894	1.375	1.689	1.693	1.341	1.381	1.217	132	163	120	90	112	85	CBX2	chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552]	-	-	-	-	GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0007548//sex differentiation;GO:0030154//cell differentiation;GO:0045137//development of primary sexual characteristics	--
ENSG00000173898	47.346	52.279	59.628	53.047	53.724	48.146	8495.75	9425	7848	6993	8138	6347	SPTBN2	"spectrin beta, non-erythrocytic 2 [Source:HGNC Symbol;Acc:HGNC:11276]"	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05017//Spinocerebellar ataxia	K23932;K23932	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0033010//paranodal junction;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099189//postsynaptic spectrin-associated cytoskeleton	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0098918//structural constituent of synapse	GO:0007154//cell communication;GO:0007416//synapse assembly;GO:0016192//vesicle-mediated transport;GO:0021692//cerebellar Purkinje cell layer morphogenesis;GO:0023052//signaling;GO:0030036//actin cytoskeleton organization;GO:0030534//adult behavior;GO:0035264//multicellular organism growth;GO:0050896//response to stimulus;GO:0051641//cellular localization;GO:0051693//actin filament capping;GO:0099173//postsynapse organization	--
ENSG00000173905	9.608	9.654	8.056	3.613	5.754	5.965	742	727	453	233	385	350	GOLIM4	golgi integral membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:15448]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0005801//cis-Golgi network;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030139//endocytic vesicle;GO:0032580//Golgi cisterna membrane	-	-	--
ENSG00000173908	0	0	0	0	0	0	0	0	0	0	0	0	KRT28	keratin 28 [Source:HGNC Symbol;Acc:HGNC:30842]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000173914	12.376	12.335	13.05	13.682	12.22	12.447	457.92	461.57	321.69	342.55	385.5	339.94	RBM4B	RNA binding motif protein 4B [Source:HGNC Symbol;Acc:HGNC:28842]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0007623//circadian rhythm;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0032922//circadian regulation of gene expression;GO:0043153//entrainment of circadian clock by photoperiod"	--
ENSG00000173915	32.092	40.877	32.27	38.736	35.503	49.51	252	324	186	223	235	289	ATP5MK	ATP synthase membrane subunit k [Source:HGNC Symbol;Acc:HGNC:30889]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0015986//ATP synthesis coupled proton transport	--
ENSG00000173917	0	0	0	0.039	0.068	0	0	0	0	1	2	0	HOXB2	homeobox B2 [Source:HGNC Symbol;Acc:HGNC:5113]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002011//morphogenesis of an epithelial sheet;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0008015//blood circulation;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0021569//rhombomere 3 development;GO:0021570//rhombomere 4 development;GO:0021612//facial nerve structural organization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0048857//neural nucleus development"	Homeobox
ENSG00000173918	39.538	42.631	47.251	41.882	43.951	47.167	2041	2238	1831	1631	1941	1772	C1QTNF1	C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0042802//identical protein binding	GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010544//negative regulation of platelet activation;GO:0010628//positive regulation of gene expression;GO:0010906//regulation of glucose metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0051897//positive regulation of protein kinase B signaling;GO:0090331//negative regulation of platelet aggregation;GO:2000860//positive regulation of aldosterone secretion	--
ENSG00000173926	0.611	0.498	0.571	0.978	0.723	0.933	50	41	31	38	50	43	MARCHF3	membrane associated ring-CH-type finger 3 [Source:HGNC Symbol;Acc:HGNC:28728]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0016567//protein ubiquitination	--
ENSG00000173928	1.49	1.13	1.304	1.604	1.27	2.041	31	23	20	28	23	29	SWSAP1	SWIM-type zinc finger 7 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:26638]	-	-	-	-	GO:0005634//nucleus;GO:0097196//Shu complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0016887//ATP hydrolysis activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0050821//protein stabilization	--
ENSG00000173930	0.209	0.132	0.052	0.077	0.113	0.157	22	14	4	6	10	12	SLCO4C1	solute carrier organic anion transporter family member 4C1 [Source:HGNC Symbol;Acc:HGNC:23612]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000173933	58.368	59.638	72.633	77.675	60.831	68.083	1762.75	1767.94	1474.74	1526.77	1543.03	1449.7	RBM4	RNA binding motif protein 4 [Source:HGNC Symbol;Acc:HGNC:9901]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030332//cyclin binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0097157//pre-mRNA intronic binding;GO:0097158//pre-mRNA intronic pyrimidine-rich binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0002190//cap-independent translational initiation;GO:0002192//IRES-dependent translational initiation of linear mRNA;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0032055//negative regulation of translation in response to stress;GO:0035278//miRNA mediated inhibition of translation;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045947//negative regulation of translational initiation;GO:0046685//response to arsenic-containing substance;GO:0046822//regulation of nucleocytoplasmic transport;GO:0051149//positive regulation of muscle cell differentiation;GO:0097167//circadian regulation of translation"	--
ENSG00000173947	8.673	9.85	8.528	8.402	6.995	8.652	360	406	245	180	203	255	PIFO	primary cilia formation [Source:HGNC Symbol;Acc:HGNC:27009]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0031267//small GTPase binding;GO:0043015//gamma-tubulin binding;GO:0048487//beta-tubulin binding	GO:0030030//cell projection organization;GO:0031344//regulation of cell projection organization;GO:0033674//positive regulation of kinase activity;GO:0044782//cilium organization;GO:0060971//embryonic heart tube left/right pattern formation	--
ENSG00000173950	13.405	14.053	15.491	14.193	14.056	11.974	744	789	636	578	659	489	XXYLT1	xyloside xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26639]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K23800	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0000287//magnesium ion binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0035252//UDP-xylosyltransferase activity;GO:0046872//metal ion binding;GO:0140560//xylosyl alpha-1,3-xylosyltransferase activity"	GO:0016266//O-glycan processing	--
ENSG00000173960	6.27	6.103	5.577	6.162	4.98	5.73	576	519	375	367	406	348	UBXN2A	UBX domain protein 2A [Source:HGNC Symbol;Acc:HGNC:27265]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K24349	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005801//cis-Golgi network;GO:0005829//cytosol	GO:0005515//protein binding;GO:0033130//acetylcholine receptor binding;GO:0043130//ubiquitin binding	GO:0000045//autophagosome assembly;GO:0007030//Golgi organization;GO:0031396//regulation of protein ubiquitination;GO:0031468//nuclear membrane reassembly;GO:0042176//regulation of protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0061025//membrane fusion;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000173976	0	0	0	0	0	0	0	0	0	0	0	0	RAX2	retina and anterior neural fold homeobox 2 [Source:HGNC Symbol;Acc:HGNC:18286]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050896//response to stimulus"	Homeobox
ENSG00000173988	0.065	0.056	0	0	0	0.16	2	2	0	0	0	2	LRRC63	leucine rich repeat containing 63 [Source:HGNC Symbol;Acc:HGNC:34296]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000173991	0.402	0.082	0.204	0	0.217	0.276	8	1	3	0	3	4	TCAP	titin-cap [Source:HGNC Symbol;Acc:HGNC:11610]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0031674//I band;GO:1990733//titin-telethonin complex	GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0030674//protein-macromolecule adaptor activity;GO:0031432//titin binding;GO:0036122//BMP binding;GO:0044325//transmembrane transporter binding;GO:0051373//FATZ binding;GO:0070080//titin Z domain binding	GO:0001756//somitogenesis;GO:0003009//skeletal muscle contraction;GO:0003300//cardiac muscle hypertrophy;GO:0007512//adult heart development;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030240//skeletal muscle thin filament assembly;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0030916//otic vesicle formation;GO:0035994//response to muscle stretch;GO:0035995//detection of muscle stretch;GO:0045214//sarcomere organization;GO:0048769//sarcomerogenesis;GO:0050982//detection of mechanical stimulus;GO:0055003//cardiac myofibril assembly;GO:0055008//cardiac muscle tissue morphogenesis;GO:0055013//cardiac muscle cell development;GO:0060048//cardiac muscle contraction;GO:0065003//protein-containing complex assembly	--
ENSG00000173992	8.62	11.554	10.731	11.125	10.942	10.364	187	254	171	182	202	163	CCS	copper chaperone for superoxide dismutase [Source:HGNC Symbol;Acc:HGNC:1613]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K04569;K04569	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0006801//superoxide metabolic process;GO:0015680//protein maturation by copper ion transfer;GO:0019430//removal of superoxide radicals;GO:0034599//cellular response to oxidative stress;GO:0051353//positive regulation of oxidoreductase activity	--
ENSG00000174004	0.34	0.413	0.485	0.306	0.536	0.467	18	22	19	12	24	18	NRROS	negative regulator of reactive oxygen species [Source:HGNC Symbol;Acc:HGNC:24613]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0050431//transforming growth factor beta binding	GO:0006801//superoxide metabolic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0014005//microglia development;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0036364//transforming growth factor beta1 activation	--
ENSG00000174007	3.269	3.19	3.521	1.655	1.719	3.193	132	140	108	50	65	104	CEP19	centrosomal protein 19 [Source:HGNC Symbol;Acc:HGNC:28209]	-	-	-	-	GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	"GO:0030030//cell projection organization;GO:0034454//microtubule anchoring at centrosome;GO:0060271//cilium assembly;GO:0097712//vesicle targeting, trans-Golgi to periciliary membrane compartment"	--
ENSG00000174010	4.21	3.759	3.791	3.362	3.818	3.528	522	470	367	280	413	320	KLHL15	kelch like family member 15 [Source:HGNC Symbol;Acc:HGNC:29347]	-	-	-	-	GO:0005634//nucleus;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0071630//nuclear protein quality control by the ubiquitin-proteasome system;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000174013	3.229	2.8	3.282	2.769	2.889	3.189	284	243	224	197	221	210	FBXO45	F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0019005//SCF ubiquitin ligase complex;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol	GO:0005515//protein binding	GO:0001764//neuron migration;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007399//nervous system development;GO:0016567//protein ubiquitination;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021800//cerebral cortex tangential migration;GO:0021957//corticospinal tract morphogenesis;GO:0021960//anterior commissure morphogenesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0060384//innervation;GO:0060386//synapse assembly involved in innervation	--
ENSG00000174015	0.064	0	0	0.13	0.261	0.176	2	0	0	3	3	4	CBY2	chibby family member 2 [Source:HGNC Symbol;Acc:HGNC:30720]	-	-	-	-	GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000174016	0.016	0	0	0	0	0	1	0	0	0	0	0	TENT5D	terminal nucleotidyltransferase 5D [Source:HGNC Symbol;Acc:HGNC:28399]	-	-	-	-	-	GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:1990817//RNA adenylyltransferase activity	GO:0048255//mRNA stabilization	--
ENSG00000174021	113.504	105.521	103.308	98.631	91.402	102.533	1928	1802	1294	1230	1307	1267	GNG5	G protein subunit gamma 5 [Source:HGNC Symbol;Acc:HGNC:4408]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542;K04542	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000174032	17.101	16.964	16.058	14.221	14.529	15.976	1117	1050	801	722	719	807	SLC25A30	solute carrier family 25 member 30 [Source:HGNC Symbol;Acc:HGNC:27371]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0015116//sulfate transmembrane transporter activity;GO:0015117//thiosulfate transmembrane transporter activity;GO:0015131//oxaloacetate transmembrane transporter activity;GO:0015140//malate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015297//antiporter activity	GO:0006839//mitochondrial transport;GO:0008150//biological_process;GO:0008272//sulfate transport;GO:0015709//thiosulfate transport;GO:0015729//oxaloacetate transport;GO:0035435//phosphate ion transmembrane transport;GO:0071422//succinate transmembrane transport;GO:0071423//malate transmembrane transport;GO:1902356//oxaloacetate(2-) transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000174038	0	0	0	0.02	0.089	0	0	0	0	1	2	0	C9orf131	chromosome 9 open reading frame 131 [Source:HGNC Symbol;Acc:HGNC:31418]	-	-	-	-	-	-	-	--
ENSG00000174059	0	0.019	0.026	0.008	0.04	0	0	1	1	1	2	0	CD34	CD34 molecule [Source:HGNC Symbol;Acc:HGNC:1662]	Organismal Systems;Environmental Information Processing	Immune system;Signaling molecules and interaction	ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules	K06474;K06474	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0036053//glomerular endothelium fenestra;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043199//sulfate binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001894//tissue homeostasis;GO:0001935//endothelial cell proliferation;GO:0003094//glomerular filtration;GO:0003158//endothelium development;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030097//hemopoiesis;GO:0030195//negative regulation of blood coagulation;GO:0032703//negative regulation of interleukin-2 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0035759//mesangial cell-matrix adhesion;GO:0038001//paracrine signaling;GO:0042482//positive regulation of odontogenesis;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0048870//cell motility;GO:0050900//leukocyte migration;GO:0060290//transdifferentiation;GO:0061042//vascular wound healing;GO:0071425//hematopoietic stem cell proliferation;GO:0071636//positive regulation of transforming growth factor beta production;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0071971//extracellular exosome assembly;GO:0072011//glomerular endothelium development;GO:0072089//stem cell proliferation;GO:0072254//metanephric glomerular mesangial cell differentiation;GO:0098609//cell-cell adhesion;GO:1900035//negative regulation of cellular response to heat;GO:1900038//negative regulation of cellular response to hypoxia;GO:1900168//positive regulation of glial cell-derived neurotrophic factor production;GO:1901215//negative regulation of neuron death;GO:2001214//positive regulation of vasculogenesis	--
ENSG00000174080	0	0	0	0	0.167	0	0	0	0	0	5	0	CTSF	cathepsin F [Source:HGNC Symbol;Acc:HGNC:2531]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K01373;K01373	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000174099	12.904	12.394	12.69	11.709	10.958	12.085	1153	1114	841	780	835	764	MSRB3	methionine sulfoxide reductase B3 [Source:HGNC Symbol;Acc:HGNC:27375]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0046872//metal ion binding"	GO:0006979//response to oxidative stress;GO:0030091//protein repair	--
ENSG00000174106	8.714	8.67	8.044	7.843	7.163	8.262	864	864	589	576	600	596	LEMD3	LEM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28887]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding	GO:0006997//nucleus organization;GO:0006998//nuclear envelope organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0032926//negative regulation of activin receptor signaling pathway;GO:1902531//regulation of intracellular signal transduction	--
ENSG00000174109	4.364	5.231	4.769	6.033	5.663	7.804	83	100	67	85	91	108	C16orf91	chromosome 16 open reading frame 91 [Source:HGNC Symbol;Acc:HGNC:27558]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000174123	0	0	0	0	0	0	0	0	0	0	0	0	TLR10	toll like receptor 10 [Source:HGNC Symbol;Acc:HGNC:15634]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	"GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0034166//toll-like receptor 10 signaling pathway;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response	--
ENSG00000174125	1.821	1.666	0.939	0.937	1.7	0.98	104.98	86	41	40	62	42	TLR1	toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05152//Tuberculosis;ko04620//Toll-like receptor signaling pathway	K05398;K05398	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0035354//Toll-like receptor 1-Toll-like receptor 2 protein complex;GO:0043235//receptor complex;GO:0045121//membrane raft	"GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035663//Toll-like receptor 2 binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating;GO:0071723//lipopeptide binding"	GO:0001775//cell activation;GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034130//toll-like receptor 1 signaling pathway;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0042116//macrophage activation;GO:0042495//detection of triacyl bacterial lipopeptide;GO:0045087//innate immune response;GO:0071221//cellular response to bacterial lipopeptide;GO:0071727//cellular response to triacyl bacterial lipopeptide	--
ENSG00000174130	0.047	0.03	0.022	0.01	0.043	0.063	4.02	2	2	1	5	3	TLR6	toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711]	Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cardiovascular disease;Infectious disease: parasitic;Immune system	ko05132//Salmonella infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05417//Lipid and atherosclerosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway	K10169;K10169;K10169;K10169;K10169;K10169	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0035355//Toll-like receptor 2-Toll-like receptor 6 protein complex;GO:0043235//receptor complex;GO:0045121//membrane raft	"GO:0001540//amyloid-beta binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0035663//Toll-like receptor 2 binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating;GO:0071723//lipopeptide binding"	GO:0001774//microglial cell activation;GO:0001775//cell activation;GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0010628//positive regulation of gene expression;GO:0032493//response to bacterial lipoprotein;GO:0032717//negative regulation of interleukin-8 production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034150//toll-like receptor 6 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0042496//detection of diacyl bacterial lipopeptide;GO:0042742//defense response to bacterium;GO:0043032//positive regulation of macrophage activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0046209//nitric oxide metabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071221//cellular response to bacterial lipopeptide;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1903223//positive regulation of oxidative stress-induced neuron death;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904646//cellular response to amyloid-beta	--
ENSG00000174132	8.354	7.938	7.862	6.069	5.941	8.289	223	213	155	120	134	161	FAM174A	family with sequence similarity 174 member A [Source:HGNC Symbol;Acc:HGNC:24943]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000174136	7.967	7.025	7.641	7.536	7.295	9.666	740	656	524	520	572	656	RGMB	repulsive guidance molecule BMP co-receptor b [Source:HGNC Symbol;Acc:HGNC:26896]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K06847	GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0042802//identical protein binding	"GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030509//BMP signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000174137	1.127	1.389	0.787	0.787	1.191	1.537	40	51	26	34	35	47	FAM53A	family with sequence similarity 53 member A [Source:HGNC Symbol;Acc:HGNC:31860]	-	-	-	-	GO:0005634//nucleus	-	GO:0006606//protein import into nucleus	--
ENSG00000174145	0	0	0	0	0	0	0	0	0	0	0	0	NWD2	NACHT and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29229]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000174151	2.716	3.172	3.016	3.236	4.232	4.69	254	248	222	199	243	217	CYB561D1	cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0140571//transmembrane ascorbate ferrireductase activity;GO:0140575//transmembrane monodehydroascorbate reductase activity	GO:0055085//transmembrane transport	--
ENSG00000174156	0.053	0	0	0	0	0	1	0	0	0	0	0	GSTA3	glutathione S-transferase alpha 3 [Source:HGNC Symbol;Acc:HGNC:4628]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006629//lipid metabolic process;GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000174165	5.469	5.358	4.655	6.635	6.826	6.274	378	381	270	365	396	303	ZDHHC24	zinc finger DHHC-type containing 24 [Source:HGNC Symbol;Acc:HGNC:27387]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation	--
ENSG00000174173	8.561	7.852	8.364	7.498	6.77	8.856	283	293	202	200	205	219	TRMT10C	"tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:HGNC Symbol;Acc:HGNC:26022]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030678//mitochondrial ribonuclease P complex;GO:0042645//mitochondrial nucleoid;GO:0043527//tRNA methyltransferase complex	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0009019//tRNA (guanine-N1-)-methyltransferase activity;GO:0016429//tRNA (adenine-N1-)-methyltransferase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0052905//tRNA (guanine(9)-N(1))-methyltransferase activity;GO:0061953//mRNA (adenine-N1-)-methyltransferase activity	GO:0000964//mitochondrial RNA 5'-end processing;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0070131//positive regulation of mitochondrial translation;GO:0070901//mitochondrial tRNA methylation;GO:0080009//mRNA methylation;GO:0090646//mitochondrial tRNA processing;GO:0097745//mitochondrial tRNA 5'-end processing;GO:1990180//mitochondrial tRNA 3'-end processing	--
ENSG00000174175	0.199	0.355	0.058	0.687	0.679	0.7	13	23	2	21	32	28	SELP	selectin P [Source:HGNC Symbol;Acc:HGNC:10721]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Infectious disease: viral;Immune system;Cardiovascular disease;Infectious disease: bacterial;Signaling molecules and interaction;Infectious disease: parasitic	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko05417//Lipid and atherosclerosis;ko05150//Staphylococcus aureus infection;ko04514//Cell adhesion molecules;ko05144//Malaria	K06496;K06496;K06496;K06496;K06496;K06496	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031088//platelet dense granule membrane;GO:0031092//platelet alpha granule membrane	GO:0001530//lipopolysaccharide binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding;GO:0042806//fucose binding;GO:0043208//glycosphingolipid binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0070492//oligosaccharide binding	GO:0002687//positive regulation of leukocyte migration;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0010572//positive regulation of platelet activation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0032496//response to lipopolysaccharide;GO:0033623//regulation of integrin activation;GO:0034097//response to cytokine;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0050829//defense response to Gram-negative bacterium;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000174177	4.937	5.863	6.583	5.144	5.728	7.069	173	208	170	132	173	183	CTU2	cytosolic thiouridylase subunit 2 [Source:HGNC Symbol;Acc:HGNC:28005]	Genetic Information Processing	"Folding, sorting and degradation"	ko04122//Sulfur relay system	K14169	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000049//tRNA binding;GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity;GO:0016783//sulfurtransferase activity	GO:0002098//tRNA wobble uridine modification;GO:0002143//tRNA wobble position uridine thiolation;GO:0008033//tRNA processing;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification	--
ENSG00000174197	4.842	4.159	3.165	2.34	2.808	2.967	1031	880	556	383	534	476	MGA	MAX dimerization protein MGA [Source:HGNC Symbol;Acc:HGNC:14010]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0001708//cell fate specification;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	T-box
ENSG00000174206	1.657	1.582	1.159	1.793	2.619	1.411	127	109	54	97	137	82	KICS2	KICSTOR subunit 2 [Source:HGNC Symbol;Acc:HGNC:26517]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0140007//KICSTOR complex	GO:0005515//protein binding	GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0061462//protein localization to lysosome;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000174225	0	0	0.043	0.042	0	0	0	0	1	1	0	0	ARL13A	ADP ribosylation factor like GTPase 13A [Source:HGNC Symbol;Acc:HGNC:31709]	-	-	-	-	GO:0031514//motile cilium;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0097500//receptor localization to non-motile cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000174226	0	0	0	0	0	0	0	0	0	0	0	0	SNX31	sorting nexin 31 [Source:HGNC Symbol;Acc:HGNC:28605]	-	-	-	-	GO:0005769//early endosome;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000174227	16.831	16.357	16.088	16.021	16.624	20.434	1104	1104	784	794	938	968	PIGG	phosphatidylinositol glycan anchor biosynthesis class G [Source:HGNC Symbol;Acc:HGNC:25985]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05310;K05310	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0051267//CP2 mannose-ethanolamine phosphotransferase activity;GO:0051377//mannose-ethanolamine phosphotransferase activity"	GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane	--
ENSG00000174231	70.78	78.515	80.195	73.919	78.147	71.332	10693	11896	8955	8254	9981	7847	PRPF8	pre-mRNA processing factor 8 [Source:HGNC Symbol;Acc:HGNC:17340]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12856	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030532//small nuclear ribonucleoprotein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0030619//U1 snRNA binding;GO:0030620//U2 snRNA binding;GO:0030623//U5 snRNA binding;GO:0070122//isopeptidase activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0097157//pre-mRNA intronic binding;GO:0140492//metal-dependent deubiquitinase activity	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor"	--
ENSG00000174233	6.461	5.512	5.989	5.977	7.068	6.4	748	704	562	564	669	593	ADCY6	adenylate cyclase 6 [Source:HGNC Symbol;Acc:HGNC:237]	Metabolism;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Immune system;Signal transduction;Cardiovascular disease;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Nucleotide metabolism;Endocrine system;Immune system;Endocrine system;Nervous system;Nervous system;Endocrine system;Endocrine system;Digestive system;Environmental adaptation;Endocrine system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Digestive system;Endocrine system;Aging;Substance dependence;Cellular community - eukaryotes;Digestive system;Nervous system;Endocrine system;Sensory system;Digestive system;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine system;Excretory system;Excretory system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko00230//Purine metabolism;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04928//Parathyroid hormone synthesis, secretion and action;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05032//Morphine addiction;ko04540//Gap junction;ko04976//Bile secretion;ko04727//GABAergic synapse;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04924//Renin secretion;ko04213//Longevity regulating pathway - multiple species;ko04927//Cortisol synthesis and secretion;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04962//Vasopressin-regulated water reabsorption"	K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046;K08046	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane;GO:0032420//stereocilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding	GO:0003091//renal water homeostasis;GO:0006171//cAMP biosynthetic process;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0009190//cyclic nucleotide biosynthetic process;GO:0010977//negative regulation of neuron projection development;GO:0035556//intracellular signal transduction;GO:0035811//negative regulation of urine volume;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071870//cellular response to catecholamine stimulus;GO:0097746//blood vessel diameter maintenance;GO:1904117//cellular response to vasopressin;GO:1904322//cellular response to forskolin	--
ENSG00000174236	0.042	0.042	0.057	0	0.198	0.288	1	1	1	0	4	5	REP15	RAB15 effector protein [Source:HGNC Symbol;Acc:HGNC:33748]	-	-	-	-	GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome	GO:0005515//protein binding	GO:0001881//receptor recycling;GO:0033572//transferrin transport	--
ENSG00000174238	178.838	179.254	170.467	161.839	167.626	127.211	10696	10650	7262	6934	8509	5453	PITPNA	phosphatidylinositol transfer protein alpha [Source:HGNC Symbol;Acc:HGNC:9001]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transfer activity;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0070540//stearic acid binding;GO:0120019//phosphatidylcholine transfer activity;GO:1901611//phosphatidylglycerol binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0007601//visual perception;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000174243	31.175	30.488	32.704	27.595	27.98	27.717	2091	2011	1629	1378	1583	1362	DDX23	DEAD-box helicase 23 [Source:HGNC Symbol;Acc:HGNC:17347]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12858	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0070062//extracellular exosome;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000354//cis assembly of pre-catalytic spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0062176//R-loop disassembly"	--
ENSG00000174255	0	0	0	0	0	0	0	0	0	0	0	0	ZNF80	zinc finger protein 80 [Source:HGNC Symbol;Acc:HGNC:13155]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000174276	7.72	6.277	7.99	8.017	10.06	9.641	208	170	159	160	229	189	ZNHIT2	zinc finger HIT-type containing 2 [Source:HGNC Symbol;Acc:HGNC:1177]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000174279	0	0	0	0	0	0	0	0	0	0	0	0	EVX2	even-skipped homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3507]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0035108//limb morphogenesis"	Homeobox
ENSG00000174282	30.562	32.735	33.204	32.673	31.759	31.787	3721	4007	2993	2950	3270	2817	ZBTB4	zinc finger and BTB domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23847]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0010428//methyl-CpNpG binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0045892//negative regulation of transcription, DNA-templated"	ZBTB
ENSG00000174292	2.306	4.211	2.695	2.9	2.673	2.328	103	177	114	123	126	97	TNK1	tyrosine kinase non receptor 1 [Source:HGNC Symbol;Acc:HGNC:11940]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0045087//innate immune response;GO:0046777//protein autophosphorylation	--
ENSG00000174306	14.154	9.443	10.708	12.77	12.169	15.376	1806	1625	1376	1518	1683	1726	ZHX3	zinc fingers and homeoboxes 3 [Source:HGNC Symbol;Acc:HGNC:15935]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	Homeobox
ENSG00000174307	8.545	9.97	13.18	12.004	14.313	9.765	305	341	333	338	386	221	PHLDA3	pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1901981//phosphatidylinositol phosphate binding"	GO:0006915//apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0051898//negative regulation of protein kinase B signaling	--
ENSG00000174326	0.932	0.734	1.929	1.203	1.302	1.102	34	27	51	33	40	30	SLC16A11	solute carrier family 16 member 11 [Source:HGNC Symbol;Acc:HGNC:23093]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000174327	2.378	1.781	1.773	2.201	2.973	3.269	89	67	49	61	94	89	SLC16A13	solute carrier family 16 member 13 [Source:HGNC Symbol;Acc:HGNC:31037]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport	--
ENSG00000174332	0.446	0.358	0.296	0.556	0.446	0.577	26	21	13	24	22	25	GLIS1	GLIS family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:29525]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010454//negative regulation of cell fate commitment;GO:0030154//cell differentiation;GO:0045444//fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000174339	0	0	0	0	0	0	0	0	0	0	0	0	OR2Y1	olfactory receptor family 2 subfamily Y member 1 [Source:HGNC Symbol;Acc:HGNC:14837]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174343	0	0	0	0	0	0	0	0	0	0	0	0	CHRNA9	cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079]	Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Cancer: overview	ko04080//Neuroactive ligand-receptor interaction;ko05207//Chemical carcinogenesis - receptor activation	K04810;K04810	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098981//cholinergic synapse;GO:0099060//integral component of postsynaptic specialization membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0007605//sensory perception of sound;GO:0010996//response to auditory stimulus;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0042472//inner ear morphogenesis;GO:0050877//nervous system process;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0051899//membrane depolarization;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport	--
ENSG00000174348	6.074	6.903	4.634	4.613	5.063	4.389	397	449	214	221	271	202	PODN	podocan [Source:HGNC Symbol;Acc:HGNC:23174]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0008285//negative regulation of cell population proliferation;GO:0030336//negative regulation of cell migration	--
ENSG00000174358	0	0	0	0	0	0	0	0	0	0	0	0	SLC6A19	solute carrier family 6 member 19 [Source:HGNC Symbol;Acc:HGNC:27960]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04974//Protein digestion and absorption;ko04978//Mineral absorption	K05334;K05334	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0007584//response to nutrient;GO:0015804//neutral amino acid transport;GO:0019058//viral life cycle;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport	--
ENSG00000174370	0.401	0.571	0.362	0.307	0.6	0.238	30	43	20	17	38	13	C11orf45	chromosome 11 open reading frame 45 [Source:HGNC Symbol;Acc:HGNC:28584]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000174371	0.148	0.486	0.461	0.869	0.159	0.613	8	12	8	13	8	25	EXO1	exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3511]	Genetic Information Processing	Replication and repair	ko03430//Mismatch repair	K10746	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016604//nuclear body	"GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0017108//5'-flap endonuclease activity;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0046872//metal ion binding;GO:0048256//flap endonuclease activity;GO:0051908//double-stranded DNA 5'-3' exodeoxyribonuclease activity"	"GO:0002376//immune system process;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006310//DNA recombination;GO:0006807//nitrogen compound metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0043170//macromolecule metabolic process;GO:0044238//primary metabolic process;GO:0045190//isotype switching;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090656//t-circle formation"	--
ENSG00000174373	6.824	4.353	4.209	3.892	4.475	4.699	1119	718	537	442	608	609	RALGAPA1	Ral GTPase activating protein catalytic subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:17770]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0046982//protein heterodimerization activity	GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000174405	4.967	2.596	3.542	3.084	2.939	3.634	363	224	219	183	207	202	LIG4	DNA ligase 4 [Source:HGNC Symbol;Acc:HGNC:6601]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K10777	"GO:0000781//chromosome, telomeric region;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0032807//DNA ligase IV complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043229//intracellular organelle;GO:0070419//nonhomologous end joining complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003909//DNA ligase activity;GO:0003910//DNA ligase (ATP) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	"GO:0000012//single strand break repair;GO:0001701//in utero embryonic development;GO:0002328//pro-B cell differentiation;GO:0006260//DNA replication;GO:0006266//DNA ligation;GO:0006281//DNA repair;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007417//central nervous system development;GO:0008283//cell population proliferation;GO:0010165//response to X-ray;GO:0010212//response to ionizing radiation;GO:0010332//response to gamma radiation;GO:0033077//T cell differentiation in thymus;GO:0033151//V(D)J recombination;GO:0033152//immunoglobulin V(D)J recombination;GO:0033153//T cell receptor V(D)J recombination;GO:0035019//somatic stem cell population maintenance;GO:0043524//negative regulation of neuron apoptotic process;GO:0045190//isotype switching;GO:0048146//positive regulation of fibroblast proliferation;GO:0050769//positive regulation of neurogenesis;GO:0051102//DNA ligation involved in DNA recombination;GO:0051103//DNA ligation involved in DNA repair;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051402//neuron apoptotic process;GO:0071285//cellular response to lithium ion;GO:0071479//cellular response to ionizing radiation;GO:0071897//DNA biosynthetic process;GO:0075713//establishment of integrated proviral latency;GO:0097680//double-strand break repair via classical nonhomologous end joining;GO:2001252//positive regulation of chromosome organization"	--
ENSG00000174417	0	0	0	0	0	0	0	0	0	0	0	0	TRHR	thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04282;K04282	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004997//thyrotropin-releasing hormone receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway	--
ENSG00000174428	13.279	10.268	7.831	13.746	13.244	11.164	592.94	482.62	369.32	420.23	452.42	362.92	GTF2IRD2B	GTF2I repeat domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33125]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	GO:0006357//regulation of transcription by RNA polymerase II	GTF2I
ENSG00000174429	0	0.017	0	0.024	0	0	0	1	0	1	0	0	ABRA	actin binding Rho activating protein [Source:HGNC Symbol;Acc:HGNC:30655]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0030017//sarcomere	GO:0003779//actin binding;GO:0005515//protein binding	"GO:0006606//protein import into nucleus;GO:0015031//protein transport;GO:0035025//positive regulation of Rho protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity"	--
ENSG00000174437	49.61	50.804	50.34	55.048	58.366	55.736	5470	5640	4060	4594	5378	4390	ATP2A2	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 [Source:HGNC Symbol;Acc:HGNC:812]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Cardiovascular disease;Circulatory system;Neurodegenerative disease;Endocrine system;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0014801//longitudinal sarcoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031095//platelet dense tubular network membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0090534//calcium ion-transporting ATPase complex;GO:0097470//ribbon synapse	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0015662//P-type ion transporter activity;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0044325//transmembrane transporter binding;GO:0044548//S100 protein binding;GO:0046872//metal ion binding;GO:0086039//P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential	GO:0000045//autophagosome assembly;GO:0002026//regulation of the force of heart contraction;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006984//ER-nucleus signaling pathway;GO:0006996//organelle organization;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0010460//positive regulation of heart rate;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014883//transition between fast and slow fiber;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0016240//autophagosome membrane docking;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0032470//positive regulation of endoplasmic reticulum calcium ion concentration;GO:0033292//T-tubule organization;GO:0034220//ion transmembrane transport;GO:0034599//cellular response to oxidative stress;GO:0034976//response to endoplasmic reticulum stress;GO:0045822//negative regulation of heart contraction;GO:0055119//relaxation of cardiac muscle;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:0140056//organelle localization by membrane tethering;GO:1900121//negative regulation of receptor binding;GO:1903233//regulation of calcium ion-dependent exocytosis of neurotransmitter;GO:1903515//calcium ion transport from cytosol to endoplasmic reticulum;GO:1903779//regulation of cardiac conduction;GO:1990036//calcium ion import into sarcoplasmic reticulum;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000174442	4.825	3.431	3.339	1.9	2.324	4.338	231.48	238.94	132.16	87.94	135.48	121	ZWILCH	zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:1990423//RZZ complex"	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007093//mitotic cell cycle checkpoint signaling;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0034501//protein localization to kinetochore;GO:0051301//cell division	--
ENSG00000174444	1026.461	1096.726	1006.133	965.879	905.233	844.082	24447	26239	17402	16871	17734	14228	RPL4	ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:10353]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02930;K02930	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000174446	12.198	13.189	12.502	10.255	8.578	12.165	187	222.06	144	129	114.1	144.09	SNAPC5	small nuclear RNA activating complex polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:15484]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0006366//transcription by RNA polymerase II;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0042795//snRNA transcription by RNA polymerase II;GO:0042796//snRNA transcription by RNA polymerase III	--
ENSG00000174448	0	0	0.166	0	0	0.102	0	0	2	0	0	2	STARD6	StAR related lipid transfer domain containing 6 [Source:HGNC Symbol;Acc:HGNC:18066]	-	-	-	-	-	GO:0008289//lipid binding	GO:0006869//lipid transport	--
ENSG00000174450	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L2	golgin A6 family like 2 [Source:HGNC Symbol;Acc:HGNC:26695]	-	-	-	-	-	-	-	--
ENSG00000174453	0	0	0	0	0	0	0	0	0	0	0	0	VWC2L	von Willebrand factor C domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:37203]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse	GO:0005515//protein binding	GO:0030514//negative regulation of BMP signaling pathway;GO:0045666//positive regulation of neuron differentiation	--
ENSG00000174456	4.845	5.651	4.478	4.962	4.469	5.312	145	170	99	110	113	113	C12orf76	chromosome 12 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:33790]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000174460	0.154	0.044	0.119	0.148	0.078	0.06	7	2	4	5	3	2	ZCCHC12	zinc finger CCHC-type containing 12 [Source:HGNC Symbol;Acc:HGNC:27273]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000174469	0.048	0.056	0.011	0.09	0.161	0.014	6	8	1	6	10	2	CNTNAP2	contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07380	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030673//axolemma;GO:0033010//paranodal junction;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0044224//juxtaparanode region of axon	GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0007155//cell adhesion;GO:0007420//brain development;GO:0007612//learning;GO:0008038//neuron recognition;GO:0008283//cell population proliferation;GO:0019226//transmission of nerve impulse;GO:0021756//striatum development;GO:0021761//limbic system development;GO:0021794//thalamus development;GO:0021987//cerebral cortex development;GO:0030534//adult behavior;GO:0031175//neuron projection development;GO:0035176//social behavior;GO:0042297//vocal learning;GO:0045163//clustering of voltage-gated potassium channels;GO:0048812//neuron projection morphogenesis;GO:0071109//superior temporal gyrus development;GO:0071205//protein localization to juxtaparanode region of axon;GO:0071625//vocalization behavior;GO:1903598//positive regulation of gap junction assembly	--
ENSG00000174473	0.099	0	0.039	0.08	0.073	0.023	7	0	2	4	3	1	GALNTL6	polypeptide N-acetylgalactosaminyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:33844]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0018243//protein O-linked glycosylation via threonine	--
ENSG00000174482	0.792	0.983	0.772	0.985	1.275	1.067	50	62	36	46	68	48	LINGO2	leucine rich repeat and Ig domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21207]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly	--
ENSG00000174483	24.008	24.364	26.084	24.186	24.276	24.151	1502	1557	1223	1153	1327.11	1027	BBS1	Bardet-Biedl syndrome 1 [Source:HGNC Symbol;Acc:HGNC:966]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0034464//BBSome;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005113//patched binding;GO:0005119//smoothened binding;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0007601//visual perception;GO:0007608//sensory perception of smell;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0043001//Golgi to plasma membrane protein transport;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000174485	13.092	9.257	8.378	5.98	8.007	8.26	1881	1290	863	657	950	837	DENND4A	DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0032483//regulation of Rab protein signal transduction;GO:0050790//regulation of catalytic activity"	--
ENSG00000174498	0.085	0.136	0.11	0.029	0.136	0.201	4	4	3	2	6	7	IGDCC3	immunoglobulin superfamily DCC subclass member 3 [Source:HGNC Symbol;Acc:HGNC:9700]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0050885//neuromuscular process controlling balance;GO:0098609//cell-cell adhesion	--
ENSG00000174500	0.126	0.073	0.076	0.072	0.035	0.02	6	5	2	2	2	1	GCSAM	germinal center associated signaling and motility [Source:HGNC Symbol;Acc:HGNC:20253]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003779//actin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0045159//myosin II binding	GO:0050855//regulation of B cell receptor signaling pathway;GO:2000401//regulation of lymphocyte migration;GO:2000402//negative regulation of lymphocyte migration	--
ENSG00000174501	0.348	0.267	0.86	0.119	0.353	0.189	20	15.11	23	10	26	16	ANKRD36C	ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946]	-	-	-	-	-	GO:0005515//protein binding;GO:0008200//ion channel inhibitor activity	-	--
ENSG00000174502	0.021	0.021	0	0.014	0.013	0	2	2	0	1	1	0	SLC26A9	solute carrier family 26 member 9 [Source:HGNC Symbol;Acc:HGNC:14469]	Human Diseases;Organismal Systems	Cancer: overview;Digestive system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04978//Mineral absorption	K14706;K14706	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0051117//ATPase binding	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0008272//sulfate transport;GO:0010628//positive regulation of gene expression;GO:0015701//bicarbonate transport;GO:0019532//oxalate transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000174514	1.354	1.477	1.351	2.165	2.137	2.869	114	125	84	135	152	165	MFSD4A	major facilitator superfamily domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25433]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005355//glucose transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport;GO:1904659//glucose transmembrane transport	--
ENSG00000174516	3.532	3.869	5.575	4.613	4.892	5.177	194	205	221	187	215	213	PELI3	pellino E3 ubiquitin protein ligase family member 3 [Source:HGNC Symbol;Acc:HGNC:30010]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0008063//Toll signaling pathway;GO:0008592//regulation of Toll signaling pathway;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway	--
ENSG00000174521	0	0	0	0	0	0	0	0	0	0	0	0	TTC9B	tetratricopeptide repeat domain 9B [Source:HGNC Symbol;Acc:HGNC:26395]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000174527	0.166	0.022	0.379	0	0.013	0.061	15	2	5	0	1	4	MYO1H	myosin IH [Source:HGNC Symbol;Acc:HGNC:13879]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0016459//myosin complex	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000174529	0.796	1.044	1.127	1.026	1.071	1.244	22	29	23	21	25	25	TMEM81	transmembrane protein 81 [Source:HGNC Symbol;Acc:HGNC:32349]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000174547	13.801	14.215	12.95	14.847	14.756	12.863	353	330	254	301	316	252	MRPL11	mitochondrial ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:14042]	Genetic Information Processing	Translation	ko03010//Ribosome	K02867	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0070180//large ribosomal subunit rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000174562	0	0	0	0	0.247	0.036	0	0	0	0	3	1	KLK15	kallikrein related peptidase 15 [Source:HGNC Symbol;Acc:HGNC:20453]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000174564	0.027	0.134	0.068	0.036	0	0	1	5	1	1	0	0	IL20RB	interleukin 20 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6004]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05137;K05137;K05137	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0042015//interleukin-20 binding	GO:0001808//negative regulation of type IV hypersensitivity;GO:0002437//inflammatory response to antigenic stimulus;GO:0002765//immune response-inhibiting signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0032733//positive regulation of interleukin-10 production;GO:0032753//positive regulation of interleukin-4 production;GO:0042130//negative regulation of T cell proliferation;GO:0048873//homeostasis of number of cells within a tissue;GO:0050863//regulation of T cell activation	--
ENSG00000174567	0.186	0.371	0.168	0.923	0.515	0.512	3	6	2	11	7	6	GOLT1A	golgi transport 1A [Source:HGNC Symbol;Acc:HGNC:24766]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0008150//biological_process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000174574	65.758	58.834	59.336	55.739	53.34	68.552	3098	2959	2165	2036	2239	2493	AKIRIN1	akirin 1 [Source:HGNC Symbol;Acc:HGNC:25744]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	GO:0003712//transcription coregulator activity;GO:0005515//protein binding	GO:0010592//positive regulation of lamellipodium assembly;GO:0010759//positive regulation of macrophage chemotaxis;GO:0014839//myoblast migration involved in skeletal muscle regeneration;GO:0045663//positive regulation of myoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation;GO:1902725//negative regulation of satellite cell differentiation	--
ENSG00000174576	0	0	0	0	0	0	0	0	0	0	0	0	NPAS4	neuronal PAS domain protein 4 [Source:HGNC Symbol;Acc:HGNC:18983]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0098794//postsynapse	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007612//learning;GO:0007614//short-term memory;GO:0007616//long-term memory;GO:0030154//cell differentiation;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035176//social behavior;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0060079//excitatory postsynaptic potential;GO:0060080//inhibitory postsynaptic potential;GO:0071386//cellular response to corticosterone stimulus;GO:1904862//inhibitory synapse assembly"	bHLH
ENSG00000174579	6.877	6.013	7.978	5.335	8.376	6.558	610	521	360	342	461	410	MSL2	MSL complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25544]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0072487//MSL complex	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0016567//protein ubiquitination;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000174586	2.115	2.114	2.939	2.78	2.45	2.626	152	132	156	118	133	122	ZNF497	zinc finger protein 497 [Source:HGNC Symbol;Acc:HGNC:23714]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000174599	1.644	1.707	1.258	1.126	1.89	1.638	69	72	39	35	67	50	TRAM1L1	translocation associated membrane protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28371]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14010	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding	"GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0015031//protein transport;GO:0045048//protein insertion into ER membrane"	--
ENSG00000174600	1.388	0.464	0.913	0.418	0.739	0.563	65	47	26	21	18	38	CMKLR1	chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0097003//adipokinetic hormone receptor activity;GO:0097004//adipokinetic hormone binding	GO:0001501//skeletal system development;GO:0002430//complement receptor mediated signaling pathway;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010759//positive regulation of macrophage chemotaxis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032695//negative regulation of interleukin-12 production;GO:0045600//positive regulation of fat cell differentiation;GO:0050848//regulation of calcium-mediated signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000174606	5.136	4.113	4.474	4.69	4.248	5.307	449	379	291	333	337	372	ANGEL2	angel homolog 2 [Source:HGNC Symbol;Acc:HGNC:30534]	-	-	-	-	GO:0005737//cytoplasm;GO:0015030//Cajal body	GO:0000175//3'-5'-exoribonuclease activity;GO:0003730//mRNA 3'-UTR binding;GO:0003824//catalytic activity	"GO:0045930//negative regulation of mitotic cell cycle;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000174607	4.178	3.346	5.062	5.313	4.986	6.499	224	226	198	261	290	319	UGT8	UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism	K04628;K04628;K04628	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0003851//2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity;GO:0008194//UDP-glycosyltransferase activity;GO:0008489//UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047263//N-acylsphingosine galactosyltransferase activity"	GO:0002175//protein localization to paranode region of axon;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006682//galactosylceramide biosynthetic process;GO:0006687//glycosphingolipid metabolic process;GO:0007010//cytoskeleton organization;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0030913//paranodal junction assembly;GO:0048812//neuron projection morphogenesis	--
ENSG00000174611	5.836	5.967	6.592	7.238	6.777	6.047	544	558	508	532	598	455	KY	kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030018//Z disc	GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000174628	12.906	10.307	9.208	8.826	9.59	7.551	480.07	395.07	252.56	227.42	312.42	211.16	IQCK	IQ motif containing K [Source:HGNC Symbol;Acc:HGNC:28556]	-	-	-	-	-	-	-	--
ENSG00000174640	0.05	0.079	0.034	0.034	0.152	0.098	2	4	1	1	6	6	SLCO2A1	solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0015132//prostaglandin transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006869//lipid transport;GO:0015732//prostaglandin transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000174652	6.414	6.331	6.629	4.995	5.396	5.627	444	448	338	261	317	290	ZNF266	zinc finger protein 266 [Source:HGNC Symbol;Acc:HGNC:13059]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000174667	0	0	0	0	0	0	0	0	0	0	0	0	OR7D4	olfactory receptor family 7 subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:8380]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174669	7.237	6.64	9.347	10.498	9.349	11.89	366	338	352	394	402	438	SLC29A2	solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004]	Human Diseases	Substance dependence	ko05034//Alcoholism	K15014	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0031965//nuclear membrane;GO:0098793//presynapse	GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005337//nucleoside transmembrane transporter activity;GO:0015211//purine nucleoside transmembrane transporter activity;GO:0015213//uridine transmembrane transporter activity	GO:0001504//neurotransmitter uptake;GO:0006836//neurotransmitter transport;GO:0007595//lactation;GO:0015853//adenine transport;GO:0015854//guanine transport;GO:0015858//nucleoside transport;GO:0015860//purine nucleoside transmembrane transport;GO:0015862//uridine transport;GO:0032238//adenosine transport;GO:0032869//cellular response to insulin stimulus;GO:0035344//hypoxanthine transport;GO:0035364//thymine transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0098810//neurotransmitter reuptake;GO:0150104//transport across blood-brain barrier;GO:1901642//nucleoside transmembrane transport	--
ENSG00000174672	1.719	1.584	2.427	1.515	1.864	2.306	107	90	108	73	124	117	BRSK2	BR serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11405]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0150034//distal axon	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0051117//ATPase binding;GO:0060590//ATPase regulator activity;GO:0106310//protein serine kinase activity	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006887//exocytosis;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030010//establishment of cell polarity;GO:0030182//neuron differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0035556//intracellular signal transduction;GO:0036503//ERAD pathway;GO:0042149//cellular response to glucose starvation;GO:0043462//regulation of ATPase activity;GO:0048812//neuron projection morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051301//cell division;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0090176//microtubule cytoskeleton organization involved in establishment of planar polarity;GO:1904152//regulation of retrograde protein transport, ER to cytosol;GO:2000807//regulation of synaptic vesicle clustering"	--
ENSG00000174684	46.578	47.941	46.771	45.628	44.412	47.541	1939	2006	1438	1407	1562	1440	B4GAT1	"beta-1,4-glucuronyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15685]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K21032;K21032	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0018146//keratan sulfate biosynthetic process;GO:0035269//protein O-linked mannosylation	--
ENSG00000174695	41.504	35.497	36.113	29.079	29.73	33.233	3898	3351	2505	2023	2359	2271	TMEM167A	transmembrane protein 167A [Source:HGNC Symbol;Acc:HGNC:28330]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0009306//protein secretion;GO:0045054//constitutive secretory pathway;GO:0046907//intracellular transport	--
ENSG00000174697	0	0	0	0	0.083	0	0	0	0	0	5	0	LEP	leptin [Source:HGNC Symbol;Acc:HGNC:6553]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04152//AMPK signaling pathway;ko04920//Adipocytokine signaling pathway	K05424;K05424;K05424;K05424;K05424;K05424	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0051428//peptide hormone receptor binding;GO:1990460//leptin receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001542//ovulation from ovarian follicle;GO:0001666//response to hypoxia;GO:0001819//positive regulation of cytokine production;GO:0001890//placenta development;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0001936//regulation of endothelial cell proliferation;GO:0002021//response to dietary excess;GO:0003300//cardiac muscle hypertrophy;GO:0006006//glucose metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006112//energy reserve metabolic process;GO:0006114//glycerol biosynthetic process;GO:0006629//lipid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0007565//female pregnancy;GO:0007584//response to nutrient;GO:0007623//circadian rhythm;GO:0008203//cholesterol metabolic process;GO:0008206//bile acid metabolic process;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0008340//determination of adult lifespan;GO:0008343//adult feeding behavior;GO:0009062//fatty acid catabolic process;GO:0009892//negative regulation of metabolic process;GO:0010507//negative regulation of autophagy;GO:0010888//negative regulation of lipid storage;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014823//response to activity;GO:0019222//regulation of metabolic process;GO:0019953//sexual reproduction;GO:0021954//central nervous system neuron development;GO:0030073//insulin secretion;GO:0030217//T cell differentiation;GO:0030300//regulation of intestinal cholesterol absorption;GO:0031667//response to nutrient levels;GO:0032008//positive regulation of TOR signaling;GO:0032099//negative regulation of appetite;GO:0032310//prostaglandin secretion;GO:0032355//response to estradiol;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032814//regulation of natural killer cell activation;GO:0032817//regulation of natural killer cell proliferation;GO:0032868//response to insulin;GO:0032869//cellular response to insulin stimulus;GO:0033197//response to vitamin E;GO:0033210//leptin-mediated signaling pathway;GO:0033686//positive regulation of luteinizing hormone secretion;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0035630//bone mineralization involved in bone maturation;GO:0035904//aorta development;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0042269//regulation of natural killer cell mediated cytotoxicity;GO:0042307//positive regulation of protein import into nucleus;GO:0042445//hormone metabolic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042593//glucose homeostasis;GO:0042755//eating behavior;GO:0043066//negative regulation of apoptotic process;GO:0043270//positive regulation of ion transport;GO:0043410//positive regulation of MAPK cascade;GO:0044320//cellular response to leptin stimulus;GO:0045471//response to ethanol;GO:0045598//regulation of fat cell differentiation;GO:0045765//regulation of angiogenesis;GO:0045906//negative regulation of vasoconstriction;GO:0046325//negative regulation of glucose import;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046850//regulation of bone remodeling;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0046890//regulation of lipid biosynthetic process;GO:0048639//positive regulation of developmental growth;GO:0050790//regulation of catalytic activity;GO:0050796//regulation of insulin secretion;GO:0050810//regulation of steroid biosynthetic process;GO:0050892//intestinal absorption;GO:0050901//leukocyte tethering or rolling;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051541//elastin metabolic process;GO:0051726//regulation of cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0060587//regulation of lipoprotein lipid oxidation;GO:0060612//adipose tissue development;GO:0061037//negative regulation of cartilage development;GO:0070093//negative regulation of glucagon secretion;GO:0071298//cellular response to L-ascorbic acid;GO:0071300//cellular response to retinoic acid;GO:0090335//regulation of brown fat cell differentiation;GO:0098868//bone growth;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1900180//regulation of protein localization to nucleus;GO:1900745//positive regulation of p38MAPK cascade;GO:1904651//positive regulation of fat cell apoptotic process;GO:1990051//activation of protein kinase C activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:2000486//negative regulation of glutamine transport;GO:2000491//positive regulation of hepatic stellate cell activation	--
ENSG00000174705	7.282	8.213	6.47	6.749	6.624	6.687	1175	1332	771	787	903	785	SH3PXD2B	SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242]	-	-	-	-	GO:0002102//podosome;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0042995//cell projection	"GO:0005515//protein binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding;GO:0042169//SH2 domain binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0001501//skeletal system development;GO:0001654//eye development;GO:0006801//superoxide metabolic process;GO:0007507//heart development;GO:0022617//extracellular matrix disassembly;GO:0030154//cell differentiation;GO:0042554//superoxide anion generation;GO:0050790//regulation of catalytic activity;GO:0060348//bone development;GO:0060612//adipose tissue development;GO:0071800//podosome assembly;GO:0072657//protein localization to membrane	--
ENSG00000174718	2.049	0.769	0.708	0.48	3.01	0.842	194	100	64	46	113	73	RESF1	retroelement silencing factor 1 [Source:HGNC Symbol;Acc:HGNC:25559]	-	-	-	-	GO:0000930//gamma-tubulin complex;GO:0005634//nucleus	GO:0005515//protein binding;GO:0042393//histone binding;GO:1990226//histone methyltransferase binding	GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly	--
ENSG00000174720	6.933	6.549	6.216	3.408	4.232	4.068	304	286	194	109	156	130	LARP7	"La ribonucleoprotein 7, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:24912]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0120259//7SK snRNP;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0097322//7SK snRNA binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000494//box C/D RNA 3'-end processing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0032897//negative regulation of viral transcription;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:1904871//positive regulation of protein localization to Cajal body;GO:1905382//positive regulation of snRNA transcription by RNA polymerase II;GO:1990438//U6 2'-O-snRNA methylation"	--
ENSG00000174721	0.245	0.244	0.332	0.331	0.291	0.337	13	13	13	13	13	13	FGFBP3	fibroblast growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:23428]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix	GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding;GO:0019838//growth factor binding	GO:0007267//cell-cell signaling;GO:0043117//positive regulation of vascular permeability;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway	--
ENSG00000174738	13.807	10.386	11.518	9.021	10.2	11.945	1484	1115	923	725	935	943	NR1D2	nuclear receptor subfamily 1 group D member 2 [Source:HGNC Symbol;Acc:HGNC:7963]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048512//circadian behavior;GO:0050727//regulation of inflammatory response;GO:0050728//negative regulation of inflammatory response;GO:0055088//lipid homeostasis;GO:0097009//energy homeostasis;GO:2001014//regulation of skeletal muscle cell differentiation"	THR-like
ENSG00000174740	1.434	1.411	1.375	1.081	1.003	0.889	83	74	47	52	44	43	PABPC5	poly(A) binding protein cytoplasmic 5 [Source:HGNC Symbol;Acc:HGNC:13629]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	-	--
ENSG00000174744	15.755	16.396	17.347	18.735	16.762	17.341	463	483	377	408	415	370	BRMS1	BRMS1 transcriptional repressor and anoikis regulator [Source:HGNC Symbol;Acc:HGNC:17262]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016580//Sin3 complex;GO:0070822//Sin3-type complex	GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0051059//NF-kappaB binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0016575//histone deacetylation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0042981//regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090312//positive regulation of protein deacetylation;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:2000210//positive regulation of anoikis"	--
ENSG00000174748	1110.239	1164.66	1125.458	1260.414	1148.006	1037.414	23044	24064	17325	19387	19742	16428	RPL15	ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:10306]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02877;K02877	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000174749	1.322	0.958	0.987	1.218	1.144	0.98	242.5	176.69	133.71	165.49	177.24	130.86	FAM241A	family with sequence similarity 241 member A [Source:HGNC Symbol;Acc:HGNC:26813]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000174775	13.907	17.595	14.005	18.067	16.979	16.415	310	397	232	303	321	270	HRAS	"HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Development and regeneration;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Nervous system;Nervous system;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Aging;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Transport and catabolism;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Aging;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05132//Salmonella infection;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833;K02833	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0098978//glutamatergic synapse;GO:1905360//GTPase complex	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0007569//cell aging;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010863//positive regulation of phospholipase C activity;GO:0030335//positive regulation of cell migration;GO:0032729//positive regulation of interferon-gamma production;GO:0034260//negative regulation of GTPase activity;GO:0042088//T-helper 1 type immune response;GO:0042127//regulation of cell population proliferation;GO:0042832//defense response to protozoan;GO:0043405//regulation of MAP kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0051726//regulation of cell cycle;GO:0060612//adipose tissue development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071480//cellular response to gamma radiation;GO:0090303//positive regulation of wound healing;GO:0090314//positive regulation of protein targeting to membrane;GO:0090398//cellular senescence;GO:0097193//intrinsic apoptotic signaling pathway;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:1900029//positive regulation of ruffle assembly;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:2000630//positive regulation of miRNA metabolic process	--
ENSG00000174776	0.037	0.368	0.068	0	0.049	0	2	6	2	0	3	0	WDR49	WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000174780	30.169	29.95	28.034	19.012	21.846	21.976	2072	2009	1321	999	1216	1028	SRP72	signal recognition particle 72 [Source:HGNC Symbol;Acc:HGNC:11303]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K03108	"GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0048500//signal recognition particle"	GO:0003723//RNA binding;GO:0005047//signal recognition particle binding;GO:0005515//protein binding;GO:0008312//7S RNA binding;GO:0030911//TPR domain binding;GO:0043022//ribosome binding	GO:0006614//SRP-dependent cotranslational protein targeting to membrane	--
ENSG00000174788	0.129	0	0.512	0	0	0.208	2	0	4	0	0	2	PCP2	Purkinje cell protein 2 [Source:HGNC Symbol;Acc:HGNC:30209]	-	-	-	-	-	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0050790//regulation of catalytic activity	--
ENSG00000174791	0.448	0.489	0.585	1.095	0.401	0.968	24	26	23	38	26	40	RIN1	Ras and Rab interactor 1 [Source:HGNC Symbol;Acc:HGNC:18749]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17638	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030139//endocytic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000174792	0	0	0	0	0	0	0	0	0	0	0	0	ODAPH	odontogenesis associated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:26300]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0070169//positive regulation of biomineral tissue development;GO:0070175//positive regulation of enamel mineralization	--
ENSG00000174796	3.987	3.787	3.57	3.301	3.656	3.649	254	243	149	161	179	177	THAP6	THAP domain containing 6 [Source:HGNC Symbol;Acc:HGNC:23189]	-	-	-	-	GO:0015630//microtubule cytoskeleton	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	THAP
ENSG00000174799	0.692	0.39	0.541	0.209	0.796	0.403	77	42	42	18	50.01	34	CEP135	centrosomal protein 135 [Source:HGNC Symbol;Acc:HGNC:29086]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0007099//centriole replication;GO:0010457//centriole-centriole cohesion;GO:1902857//positive regulation of non-motile cilium assembly;GO:1904951//positive regulation of establishment of protein localization	--
ENSG00000174804	15.321	15.284	16.887	15.999	16.318	19.644	2347.45	2353.93	1911	1815.78	2112.35	2189.95	FZD4	frizzled class receptor 4 [Source:HGNC Symbol;Acc:HGNC:4042]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354;K02354	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0019955//cytokine binding;GO:0030165//PDZ domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0038023//signaling receptor activity;GO:0042803//protein homodimerization activity;GO:0042813//Wnt-activated receptor activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity	"GO:0001553//luteinization;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0007605//sensory perception of sound;GO:0010812//negative regulation of cell-substrate adhesion;GO:0016055//Wnt signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0030182//neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031987//locomotion involved in locomotory behavior;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035426//extracellular matrix-cell signaling;GO:0035567//non-canonical Wnt signaling pathway;GO:0042701//progesterone secretion;GO:0043507//positive regulation of JUN kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060070//canonical Wnt signaling pathway;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0061301//cerebellum vasculature morphogenesis;GO:0061304//retinal blood vessel morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0110135//Norrin signaling pathway;GO:0150012//positive regulation of neuron projection arborization;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000174807	0.378	0.639	0.179	0.51	0.716	0.416	20	34	7	20	32	16	CD248	CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219]	-	-	-	-	GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0050840//extracellular matrix binding;GO:1990430//extracellular matrix protein binding	GO:0008150//biological_process;GO:0008284//positive regulation of cell population proliferation;GO:0016477//cell migration;GO:0048535//lymph node development;GO:0060033//anatomical structure regression;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000174808	16.868	16.671	18.621	11.457	14.312	16.561	805	798	606	426	572	622	BTC	betacellulin [Source:HGNC Symbol;Acc:HGNC:1121]	Environmental Information Processing	Signal transduction	ko04012//ErbB signaling pathway	K09783	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000174827	0.392	0.529	0.19	0.172	0.295	0.508	10	22	6	5	10	10	PDZK1	PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:8821]	-	-	-	-	GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031528//microvillus membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005124//scavenger receptor binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0043495//protein-membrane adaptor activity;GO:0044877//protein-containing complex binding	GO:0015879//carnitine transport;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0044070//regulation of anion transport;GO:0072659//protein localization to plasma membrane;GO:0090314//positive regulation of protein targeting to membrane;GO:1904064//positive regulation of cation transmembrane transport;GO:1905477//positive regulation of protein localization to membrane;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000174837	0	0	0	0	0	0	0	0	0	0	0	0	ADGRE1	adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071944//cell periphery	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000174839	6.956	7.603	7.375	7.645	5.748	6.589	636	708	473	500	468	422	DENND6A	DENN domain containing 6A [Source:HGNC Symbol;Acc:HGNC:26635]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin	--
ENSG00000174840	5.39	5.041	4.414	4.723	5.308	5.724	681	630.01	399	414	517	483	PDE12	phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0000175//3'-5'-exoribonuclease activity;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0016787//hydrolase activity;GO:0034611//oligoribonucleotidase activity;GO:0046872//metal ion binding	"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000958//mitochondrial mRNA catabolic process;GO:0006397//mRNA processing;GO:0035457//cellular response to interferon-alpha;GO:0044528//regulation of mitochondrial mRNA stability;GO:0045070//positive regulation of viral genome replication;GO:0051607//defense response to virus;GO:0060548//negative regulation of cell death;GO:0071346//cellular response to interferon-gamma;GO:0071359//cellular response to dsRNA;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090324//negative regulation of oxidative phosphorylation;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000174842	3.128	2.463	3.018	2.999	2.19	2.201	112	103	78	87	77	64	GLMN	"glomulin, FKBP associated protein [Source:HGNC Symbol;Acc:HGNC:14373]"	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K23345	GO:0005737//cytoplasm;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex	GO:0005102//signaling receptor binding;GO:0005171//hepatocyte growth factor receptor binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0055105//ubiquitin-protein transferase inhibitor activity	"GO:0001570//vasculogenesis;GO:0001819//positive regulation of cytokine production;GO:0001843//neural tube closure;GO:0007166//cell surface receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0031397//negative regulation of protein ubiquitination;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032743//positive regulation of interleukin-2 production;GO:0040029//regulation of gene expression, epigenetic;GO:0042130//negative regulation of T cell proliferation;GO:0042327//positive regulation of phosphorylation;GO:0042692//muscle cell differentiation;GO:0072359//circulatory system development"	--
ENSG00000174844	0.035	0.036	0.121	0.186	0.037	0.032	2	7	10	11	1	2	DNAH12	dynein axonemal heavy chain 12 [Source:HGNC Symbol;Acc:HGNC:2943]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000174851	47.142	50.439	48.364	56.596	54.755	54.073	1049	1074	804	946	1043	875	YIF1A	"Yip1 interacting factor homolog A, membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:16688]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000174871	1.357	2.339	1.473	0.984	1.038	0.868	39	66	31	21	25	18	CNIH2	cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032281//AMPA glutamate receptor complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	"GO:0016192//vesicle-mediated transport;GO:0035249//synaptic transmission, glutamatergic;GO:0042391//regulation of membrane potential;GO:0051668//localization within membrane;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:1902684//negative regulation of receptor localization to synapse;GO:1903743//negative regulation of anterograde synaptic vesicle transport;GO:2000310//regulation of NMDA receptor activity;GO:2000311//regulation of AMPA receptor activity"	--
ENSG00000174876	0	0	0	0	0	0	0	0	0	0	0	0	AMY1B	amylase alpha 1B [Source:HGNC Symbol;Acc:HGNC:475]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism	K01176;K01176;K01176;K01176;K01176	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004556//alpha-amylase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0031404//chloride ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0103025//alpha-amylase activity (releasing maltohexaose)"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process	--
ENSG00000174885	0	0	0	0	0	0	0	0	0	0	0	0	NLRP6	NLR family pyrin domain containing 6 [Source:HGNC Symbol;Acc:HGNC:22944]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20863	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0043228//non-membrane-bounded organelle;GO:0061702//inflammasome complex	GO:0000166//nucleotide binding;GO:0001530//lipopolysaccharide binding;GO:0003725//double-stranded RNA binding;GO:0005000//vasopressin receptor activity;GO:0005524//ATP binding;GO:0038187//pattern recognition receptor activity;GO:0042277//peptide binding;GO:0070891//lipoteichoic acid binding;GO:0140693//molecular condensate scaffold activity	GO:0002376//immune system process;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0002526//acute inflammatory response;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006954//inflammatory response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0009617//response to bacterium;GO:0010506//regulation of autophagy;GO:0032689//negative regulation of interferon-gamma production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0042060//wound healing;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043409//negative regulation of MAPK cascade;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050777//negative regulation of immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0051260//protein homooligomerization;GO:0051607//defense response to virus;GO:0070255//regulation of mucus secretion;GO:0070266//necroptotic process;GO:0070269//pyroptosis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070946//neutrophil-mediated killing of gram-positive bacterium;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0140374//antiviral innate immune response;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway	--
ENSG00000174886	97.143	104.961	106.699	124.181	108.767	116.889	1167.96	1266.96	947.99	1109.59	1105.99	1022.96	NDUFA11	NADH:ubiquinone oxidoreductase subunit A11 [Source:HGNC Symbol;Acc:HGNC:20371]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding	GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000174891	7.539	5.883	6.976	3.021	4.693	4.88	288	266	180	97	148	151	RSRC1	arginine and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24152]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0005515//protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006468//protein phosphorylation;GO:0006913//nucleocytoplasmic transport;GO:0008380//RNA splicing;GO:0046677//response to antibiotic"	--
ENSG00000174898	0	0	0.077	0	0	0	0	0	3	0	0	0	CATSPERD	cation channel sperm associated auxiliary subunit delta [Source:HGNC Symbol;Acc:HGNC:28598]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation	--
ENSG00000174903	62.461	63.869	69.573	80.316	73.274	75.132	2418	2476	1984	2286	2360	2120	RAB1B	"RAB1B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18370]"	Human Diseases	Infectious disease: bacterial	ko05134//Legionellosis	K07875	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0034045//phagophore assembly site membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0000045//autophagosome assembly;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0019068//virion assembly;GO:1903020//positive regulation of glycoprotein metabolic process;GO:2000785//regulation of autophagosome assembly	--
ENSG00000174914	0	0	0	0	0	0	0	0	0	0	0	0	OR9G1	olfactory receptor family 9 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:15319]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174915	26.714	29.657	31.497	37.857	35.209	34.316	1362	1495	1186	1412	1512	1273	PTDSS2	phosphatidylserine synthase 2 [Source:HGNC Symbol;Acc:HGNC:15463]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K08730;K08730	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003882//CDP-diacylglycerol-serine O-phosphatidyltransferase activity;GO:0016740//transferase activity;GO:0106245//L-serine-phosphatidylethanolamine phosphatidyltransferase activity	GO:0006629//lipid metabolic process;GO:0006659//phosphatidylserine biosynthetic process;GO:0008654//phospholipid biosynthetic process	--
ENSG00000174917	20.556	18.784	19.829	27.414	24.048	24.875	224	204	158	219	220	195	MICOS13	mitochondrial contact site and cristae organizing system subunit 13 [Source:HGNC Symbol;Acc:HGNC:33702]	-	-	-	-	GO:0001401//SAM complex;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation	--
ENSG00000174928	6.754	5.528	6.549	5.917	7.641	7.646	253	206	181	164	238	208	C3orf33	chromosome 3 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:26434]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0051090//regulation of DNA-binding transcription factor activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000174937	0	0	0	0	0	0	0	0	0	0	0	0	OR5M3	olfactory receptor family 5 subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:14806]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174938	55.918	67.546	56.648	61.713	70.4	54.503	3951	4669	3027	3270	4233	2840	SEZ6L2	seizure related 6 homolog like 2 [Source:HGNC Symbol;Acc:HGNC:30844]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body	-	GO:0008344//adult locomotory behavior;GO:0021680//cerebellar Purkinje cell layer development;GO:0060074//synapse maturation;GO:0090036//regulation of protein kinase C signaling	--
ENSG00000174939	13.083	15.668	15.048	23.058	22.415	22.757	352	383	285	453.71	472	407	ASPHD1	aspartate beta-hydroxylase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27380]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016491//oxidoreductase activity;GO:0051213//dioxygenase activity	GO:0018193//peptidyl-amino acid modification	--
ENSG00000174943	3.851	4.188	3.341	5.602	4.501	5.256	154	173	101	160.29	162	152	KCTD13	potassium channel tetramerization domain containing 13 [Source:HGNC Symbol;Acc:HGNC:22234]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0016477//cell migration;GO:0016567//protein ubiquitination;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043149//stress fiber assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045740//positive regulation of DNA replication;GO:0050806//positive regulation of synaptic transmission;GO:0051260//protein homooligomerization	--
ENSG00000174944	0	0	0	0	0	0	0	0	0	0	0	0	P2RY14	purinergic receptor P2Y14 [Source:HGNC Symbol;Acc:HGNC:16442]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04299	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity;GO:0045029//G protein-coupled UDP receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway	--
ENSG00000174945	0.026	0.028	0.036	0.023	0.068	0.024	3	5	4	3	5	2	AMZ1	archaelysin family metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:22231]	-	-	-	-	GO:0005575//cellular_component	GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000174946	0	0	0	0	0	0	0	0	0	0	0	0	GPR171	G protein-coupled receptor 171 [Source:HGNC Symbol;Acc:HGNC:30057]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008188//neuropeptide receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0045638//negative regulation of myeloid cell differentiation;GO:0051930//regulation of sensory perception of pain;GO:0060259//regulation of feeding behavior	--
ENSG00000174948	0	0.009	0	0	0.021	0	0	1	0	0	2	0	GPR149	G protein-coupled receptor 149 [Source:HGNC Symbol;Acc:HGNC:23627]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0001546//preantral ovarian follicle growth;GO:0001547//antral ovarian follicle growth;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0060280//negative regulation of ovulation	--
ENSG00000174950	0.132	0.296	0.897	0.718	0.853	0.911	4	9	17	13	19	18	CD164L2	CD164 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:32043]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	-	--
ENSG00000174951	0	0.014	0	0.019	0	0.058	0	1	0	1	0	3	FUT1	fucosyltransferase 1 (H blood group) [Source:HGNC Symbol;Acc:HGNC:4012]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K00718;K00718;K00718	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0008107//galactoside 2-alpha-L-fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0031127//alpha-(1,2)-fucosyltransferase activity"	GO:0001936//regulation of endothelial cell proliferation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0010595//positive regulation of endothelial cell migration;GO:0021772//olfactory bulb development;GO:0030155//regulation of cell adhesion;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:1903672//positive regulation of sprouting angiogenesis;GO:1904906//positive regulation of endothelial cell-matrix adhesion via fibronectin	--
ENSG00000174953	15.673	11.029	12.352	8.382	10.394	12.79	1200	843	729	495	688	626	DHX36	DEAH-box helicase 36 [Source:HGNC Symbol;Acc:HGNC:14410]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14442	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0070062//extracellular exosome"	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0002151//G-quadruplex RNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0048027//mRNA 5'-UTR binding;GO:0051880//G-quadruplex DNA binding;GO:0070034//telomerase RNA binding;GO:0070883//pre-miRNA binding"	"GO:0001503//ossification;GO:0002376//immune system process;GO:0002735//positive regulation of myeloid dendritic cell cytokine production;GO:0006359//regulation of transcription by RNA polymerase III;GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0009615//response to virus;GO:0010501//RNA secondary structure unwinding;GO:0010628//positive regulation of gene expression;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0032727//positive regulation of interferon-alpha production;GO:0034605//cellular response to heat;GO:0034644//cellular response to UV;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043330//response to exogenous dsRNA;GO:0043488//regulation of mRNA stability;GO:0044806//G-quadruplex DNA unwinding;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0051607//defense response to virus;GO:0051891//positive regulation of cardioblast differentiation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0090669//telomerase RNA stabilization;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901534//positive regulation of hematopoietic progenitor cell differentiation;GO:1902064//regulation of transcription from RNA polymerase II promoter involved in spermatogenesis;GO:1903843//cellular response to arsenite ion;GO:1904358//positive regulation of telomere maintenance via telomere lengthening;GO:1904582//positive regulation of intracellular mRNA localization;GO:2000767//positive regulation of cytoplasmic translation"	--
ENSG00000174957	0	0	0	0	0	0	0	0	0	0	0	0	OR5J2	olfactory receptor family 5 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:19612]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174963	0.267	0.277	0.274	0.227	0.414	0.133	22	23	10	14	23	8	ZIC4	Zic family member 4 [Source:HGNC Symbol;Acc:HGNC:20393]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development	zf-C2H2
ENSG00000174970	0	0	0	0	0	0	0	0	0	0	0	0	OR10AG1	olfactory receptor family 10 subfamily AG member 1 [Source:HGNC Symbol;Acc:HGNC:19607]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174982	0	0	0	0	0	0	0	0	0	0	0	0	OR4S2	olfactory receptor family 4 subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:15183]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000174989	8.027	7.923	7.379	6.024	8.323	7.28	780	749	542	406	617	488	FBXW8	F-box and WD repeat domain containing 8 [Source:HGNC Symbol;Acc:HGNC:13597]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10264	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0048471//perinuclear region of cytoplasm;GO:1990393//3M complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000209//protein polyubiquitination;GO:0007030//Golgi organization;GO:0008283//cell population proliferation;GO:0016567//protein ubiquitination;GO:0043687//post-translational protein modification;GO:0050775//positive regulation of dendrite morphogenesis;GO:0060712//spongiotrophoblast layer development;GO:0060716//labyrinthine layer blood vessel development;GO:1901485//positive regulation of transcription factor catabolic process	--
ENSG00000174990	0	0	0	0	0	0	0	0	0	0	0	0	CA5A	carbonic anhydrase 5A [Source:HGNC Symbol;Acc:HGNC:1377]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process	--
ENSG00000174992	0	0	0	0	0	0	0	0	0	0	0	0	ZG16	zymogen granule protein 16 [Source:HGNC Symbol;Acc:HGNC:30961]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0031410//cytoplasmic vesicle;GO:0042589//zymogen granule membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070701//mucus layer	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042834//peptidoglycan binding	GO:0015031//protein transport;GO:0050830//defense response to Gram-positive bacterium;GO:0052373//suppression of symbiont entry into host by host	--
ENSG00000174996	10.768	11.912	15.137	15.099	13.922	16.694	652	697	658	679	690	726	KLC2	kinesin light chain 2 [Source:HGNC Symbol;Acc:HGNC:20716]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection	K10407;K10407;K10407;K10407;K10407;K10407;K10407	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016938//kinesin I complex;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0045296//cadherin binding	GO:0032418//lysosome localization	--
ENSG00000175003	0.05	0	0.09	0	0.118	0.046	2	0	2	0	3	1	SLC22A1	solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]	Human Diseases;Organismal Systems	Cancer: overview;Digestive system	ko05231//Choline metabolism in cancer;ko04976//Bile secretion	K08198;K08198	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0098793//presynapse	GO:0005277//acetylcholine transmembrane transporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005330//dopamine:sodium symporter activity;GO:0005334//norepinephrine:sodium symporter activity;GO:0005515//protein binding;GO:0008504//monoamine transmembrane transporter activity;GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015214//pyrimidine nucleoside transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0042802//identical protein binding;GO:0042910//xenobiotic transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006836//neurotransmitter transport;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0015695//organic cation transport;GO:0015697//quaternary ammonium group transport;GO:0015844//monoamine transport;GO:0015872//dopamine transport;GO:0015874//norepinephrine transport;GO:0042908//xenobiotic transport;GO:0048241//epinephrine transport;GO:0051610//serotonin uptake;GO:0051620//norepinephrine uptake;GO:0055085//transmembrane transport;GO:0072530//purine-containing compound transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0090494//dopamine uptake;GO:0098655//cation transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1901374//acetate ester transport;GO:1901998//toxin transport;GO:1990962//xenobiotic transport across blood-brain barrier	--
ENSG00000175018	0	0	0	0	0	0	0	0	0	0	0	0	TEX36	testis expressed 36 [Source:HGNC Symbol;Acc:HGNC:31653]	-	-	-	-	-	-	-	--
ENSG00000175029	22.521	19.742	26.045	19.132	22.431	23.512	1408.8	1336.97	1121.39	908.2	1077.95	1099.95	CTBP2	C-terminal binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2495]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04310//Wnt signaling pathway;ko05220//Chronic myeloid leukemia;ko04330//Notch signaling pathway	K04496;K04496;K04496;K04496	GO:0005634//nucleus;GO:0017053//transcription repressor complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0097470//ribbon synapse;GO:0098684//photoreceptor ribbon synapse;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099523//presynaptic cytosol	"GO:0001221//transcription coregulator binding;GO:0001222//transcription corepressor binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042974//retinoic acid receptor binding;GO:0044877//protein-containing complex binding;GO:0051287//NAD binding;GO:0098882//structural constituent of presynaptic active zone"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0016081//synaptic vesicle docking;GO:0019079//viral genome replication;GO:0030154//cell differentiation;GO:0035563//positive regulation of chromatin binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0048790//maintenance of presynaptic active zone structure;GO:0050872//white fat cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000175040	9.195	9.195	4.46	12.87	13.433	13.806	790	794	283	819	975	863	CHST2	carbohydrate sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:1970]	Metabolism	Glycan biosynthesis and metabolism	ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K04745	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031228//intrinsic component of Golgi membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0007275//multicellular organism development;GO:0018146//keratan sulfate biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000175048	1.596	2.246	2.958	2.103	2.347	2.871	131	150	93	126	142	146	ZDHHC14	zinc finger DHHC-type palmitoyltransferase 14 [Source:HGNC Symbol;Acc:HGNC:20341]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation	--
ENSG00000175054	3.17	2.716	2.248	1.601	2.127	1.982	534	439	272	197	297	237	ATR	ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Genetic Information Processing	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cell growth and death;Cell growth and death;Cell growth and death;Replication and repair	ko05165//Human papillomavirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04218//Cellular senescence;ko04110//Cell cycle;ko04115//p53 signaling pathway;ko03460//Fanconi anemia pathway	K06640;K06640;K06640;K06640;K06640;K06640;K06640	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0016605//PML body;GO:0070310//ATR-ATRIP complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0032405//MutLalpha complex binding;GO:0032407//MutSalpha complex binding;GO:0106310//protein serine kinase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000723//telomere maintenance;GO:0006139//nucleobase-containing compound metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0006974//cellular response to DNA damage stimulus;GO:0007275//multicellular organism development;GO:0008156//negative regulation of DNA replication;GO:0009410//response to xenobiotic stimulus;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031297//replication fork processing;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0034644//cellular response to UV;GO:0036297//interstrand cross-link repair;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0046685//response to arsenic-containing substance;GO:0046777//protein autophosphorylation;GO:0070198//protein localization to chromosome, telomeric region;GO:0071480//cellular response to gamma radiation;GO:0090399//replicative senescence;GO:0097694//establishment of RNA localization to telomere;GO:0097695//establishment of protein-containing complex localization to telomere;GO:1900034//regulation of cellular response to heat;GO:1904884//positive regulation of telomerase catalytic core complex assembly;GO:2000112//regulation of cellular macromolecule biosynthetic process;GO:2000779//regulation of double-strand break repair"	--
ENSG00000175063	0.62	1.747	2.289	2.16	1.702	1.301	10	28	27	26	23	15	UBE2C	ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K06688	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0061630//ubiquitin protein ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0010458//exit from mitosis;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031536//positive regulation of exit from mitosis;GO:0032446//protein modification by small protein conjugation;GO:0051301//cell division;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:1904668//positive regulation of ubiquitin protein ligase activity	--
ENSG00000175065	0	0	0	0	0	0	0	0	0	0	0	0	DSG4	desmoglein 4 [Source:HGNC Symbol;Acc:HGNC:21307]	-	-	-	-	GO:0001533//cornified envelope;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030057//desmosome	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0001942//hair follicle development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030216//keratinocyte differentiation;GO:0030509//BMP signaling pathway;GO:0098609//cell-cell adhesion	--
ENSG00000175066	1.667	1.611	1.171	1.184	1.56	1.735	290	214	151	145	205	198	GK5	glycerol kinase 5 [Source:HGNC Symbol;Acc:HGNC:28635]	-	-	-	-	GO:0005739//mitochondrion	"GO:0000166//nucleotide binding;GO:0004370//glycerol kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0006071//glycerol metabolic process;GO:0006641//triglyceride metabolic process;GO:0016310//phosphorylation;GO:0019563//glycerol catabolic process;GO:0046167//glycerol-3-phosphate biosynthetic process	--
ENSG00000175073	2.663	2.274	2.052	1.582	1.909	2.063	550	472	313	242	333	310	VCPIP1	valosin containing protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30897]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0007030//Golgi organization;GO:0016320//endoplasmic reticulum membrane fusion;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0090168//Golgi reassembly;GO:0106300//protein-DNA covalent cross-linking repair;GO:1905634//regulation of protein localization to chromatin	--
ENSG00000175077	0	0	0	0	0	0	0	0	0	0	0	0	RTP1	receptor transporter protein 1 [Source:HGNC Symbol;Acc:HGNC:28580]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0031849//olfactory receptor binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006612//protein targeting to membrane;GO:0051205//protein insertion into membrane	--
ENSG00000175084	12.424	11.997	5.559	9.373	8.472	6.499	578	561	191	323	333	220	DES	desmin [Source:HGNC Symbol;Acc:HGNC:2770]	Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K07610;K07610;K07610	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005916//fascia adherens;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0030018//Z disc;GO:0031594//neuromuscular junction;GO:0042383//sarcolemma;GO:0043292//contractile fiber;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular exosome;GO:0097512//cardiac myofibril	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding	GO:0006936//muscle contraction;GO:0007010//cytoskeleton organization;GO:0008016//regulation of heart contraction;GO:0045109//intermediate filament organization	--
ENSG00000175087	3.322	2.612	2.984	1.931	2.289	3.365	287	224	188	122	165	184	PDIK1L	PDLIM1 interacting kinase 1 like [Source:HGNC Symbol;Acc:HGNC:18981]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051321//meiotic cell cycle	--
ENSG00000175093	0	0	0.037	0	0	0	0	0	1	0	0	0	SPSB4	splA/ryanodine receptor domain and SOCS box containing 4 [Source:HGNC Symbol;Acc:HGNC:30630]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0042752//regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0048511//rhythmic process;GO:1902916//positive regulation of protein polyubiquitination	--
ENSG00000175097	0	0.121	0	0	0	0.055	0	6	0	0	0	2	RAG2	recombination activating 2 [Source:HGNC Symbol;Acc:HGNC:9832]	Environmental Information Processing;Human Diseases	Signal transduction;Immune disease	ko04068//FoxO signaling pathway;ko05340//Primary immunodeficiency	K10988;K10988	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0097519//DNA recombinase complex	"GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0035091//phosphatidylinositol binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0002313//mature B cell differentiation involved in immune response;GO:0002326//B cell lineage commitment;GO:0002331//pre-B cell allelic exclusion;GO:0002358//B cell homeostatic proliferation;GO:0002360//T cell lineage commitment;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0016567//protein ubiquitination;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0033151//V(D)J recombination;GO:0042742//defense response to bacterium;GO:0046622//positive regulation of organ growth	--
ENSG00000175104	5.316	4.833	5.555	4.706	4.4	4.741	558	503	437	367	393	373	TRAF6	TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	"Infectious disease: viral;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Folding, sorting and degradation;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Development and regeneration;Nervous system;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Immune system;Cancer: specific types;Infectious disease: bacterial;Immune system"	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko05152//Tuberculosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04120//Ubiquitin mediated proteolysis;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05133//Pertussis;ko04622//RIG-I-like receptor signaling pathway	K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175;K03175	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0009898//cytoplasmic side of plasma membrane;GO:0010008//endosome membrane;GO:0032991//protein-containing complex;GO:0035631//CD40 receptor complex;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043422//protein kinase B binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0001503//ossification;GO:0001701//in utero embryonic development;GO:0001843//neural tube closure;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002637//regulation of immunoglobulin production;GO:0002726//positive regulation of T cell cytokine production;GO:0002753//cytoplasmic pattern recognition receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0009887//animal organ morphogenesis;GO:0016567//protein ubiquitination;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030316//osteoclast differentiation;GO:0031398//positive regulation of protein ubiquitination;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0032735//positive regulation of interleukin-12 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032755//positive regulation of interleukin-6 production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042088//T-helper 1 type immune response;GO:0042102//positive regulation of T cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042981//regulation of apoptotic process;GO:0043011//myeloid dendritic cell differentiation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0045453//bone resorption;GO:0045672//positive regulation of osteoclast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0046849//bone remodeling;GO:0048468//cell development;GO:0050852//T cell receptor signaling pathway;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0070555//response to interleukin-1;GO:0071222//cellular response to lipopolysaccharide;GO:0071345//cellular response to cytokine stimulus;GO:0097400//interleukin-17-mediated signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:2000679//positive regulation of transcription regulatory region DNA binding"	--
ENSG00000175105	2.911	1.737	1.586	1.39	1.678	1.364	390	234	157	138	190	133	ZNF654	zinc finger protein 654 [Source:HGNC Symbol;Acc:HGNC:25612]	-	-	-	-	-	-	-	zf-C2H2
ENSG00000175106	1.241	1.949	0.896	1.434	1.322	1.343	44.29	67.85	32.63	37.19	49.7	37.54	TVP23C	trans-golgi network vesicle protein 23 homolog C [Source:HGNC Symbol;Acc:HGNC:30453]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	-	GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport	--
ENSG00000175110	11.912	13.903	15.211	11.253	10.834	11.751	326.48	367.68	301.1	224.08	244.21	227.48	MRPS22	mitochondrial ribosomal protein S22 [Source:HGNC Symbol;Acc:HGNC:14508]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0008150//biological_process;GO:0032543//mitochondrial translation	--
ENSG00000175115	26.703	27.671	22.966	28.937	28.065	24.042	2395	2582	1585	2014	2229	1624	PACS1	phosphofurin acidic cluster sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:30032]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030137//COPI-coated vesicle	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0034067//protein localization to Golgi apparatus;GO:0072659//protein localization to plasma membrane	--
ENSG00000175121	0	0	0	0	0	0	0	0	0	0	0	0	WFDC5	WAP four-disulfide core domain 5 [Source:HGNC Symbol;Acc:HGNC:20477]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000175130	121.09	119.571	113.834	97.798	92.906	90.047	3883	3854	2696	2323	2517	2101	MARCKSL1	MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142]	Organismal Systems;Human Diseases	Immune system;Infectious disease: parasitic	ko04666//Fc gamma R-mediated phagocytosis;ko05140//Leishmaniasis	K13536;K13536	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007417//central nervous system development;GO:0008284//positive regulation of cell population proliferation	--
ENSG00000175137	14.381	15.358	16.402	16.85	15.988	18.354	939	1008	791	815	882	872	SH3BP5L	SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360]	-	-	-	-	GO:0005737//cytoplasm	GO:0004860//protein kinase inhibitor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0035556//intracellular signal transduction;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000175143	0	0	0	0	0	0	0	0	0	0	0	0	OR2T1	olfactory receptor family 2 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:8277]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000175155	5.501	5.421	4.377	3.984	4.744	4.641	500	477	353	288	367	354	YPEL2	yippee like 2 [Source:HGNC Symbol;Acc:HGNC:18326]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000175161	1.63	1.584	1.121	0.947	1.45	1.308	135	98	62	63	95	95	CADM2	cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:29849]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0045202//synapse	-	GO:0007155//cell adhesion	--
ENSG00000175164	0	0	0	0	0	0	0	0	0	0	0	0	ABO	"ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase [Source:HGNC Symbol;Acc:HGNC:79]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K00709;K00709	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016758//hexosyltransferase activity	GO:0005975//carbohydrate metabolic process	--
ENSG00000175166	97.688	99.303	98.208	100.627	100.952	98.458	5772	5780	4205	4418	4963	4159	PSMD2	"proteasome 26S subunit ubiquitin receptor, non-ATPase 2 [Source:HGNC Symbol;Acc:HGNC:9559]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03028;K03028;K03028;K03028;K03028;K03028;K03028;K03028;K03028	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034515//proteasome storage granule;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0042176//regulation of protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000175175	0.272	0.234	0.229	0.159	0.113	0.182	37	32	23	16	13	18	PPM1E	"protein phosphatase, Mg2+/Mn2+ dependent 1E [Source:HGNC Symbol;Acc:HGNC:19322]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0032991//protein-containing complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006469//negative regulation of protein kinase activity;GO:0006470//protein dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0051496//positive regulation of stress fiber assembly;GO:0071466//cellular response to xenobiotic stimulus	--
ENSG00000175182	10.576	7.836	8.834	8.736	8.36	9.836	379.89	319.93	248.44	227.79	270.45	268	FAM131A	family with sequence similarity 131 member A [Source:HGNC Symbol;Acc:HGNC:28308]	-	-	-	-	-	-	-	--
ENSG00000175183	29.346	27.394	24.347	17.182	19.887	20.82	540	510	325	233	305	283	CSRP2	cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0030018//Z disc	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0042805//actinin binding;GO:0046872//metal ion binding	GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0045214//sarcomere organization;GO:0060537//muscle tissue development	--
ENSG00000175189	0.015	0	0	0	0	0	1	0	0	0	0	0	INHBC	inhibin subunit beta C [Source:HGNC Symbol;Acc:HGNC:6068]	Environmental Information Processing;Cellular Processes;Environmental Information Processing	Signaling molecules and interaction;Cellular community - eukaryotes;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K22688;K22688;K22688	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity;GO:0008083//growth factor activity	GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction	--
ENSG00000175193	13.279	12.122	10.9	16.453	13.931	15.4	389	366	240.57	344	339.17	331	PARL	presenilin associated rhomboid like [Source:HGNC Symbol;Acc:HGNC:18253]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0010821//regulation of mitochondrion organization;GO:0030162//regulation of proteolysis;GO:0033619//membrane protein proteolysis;GO:1903214//regulation of protein targeting to mitochondrion;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000175197	9.916	10.707	8.334	8.582	8.999	13.546	185	202	116	118.5	142	185	DDIT3	DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Cancer: overview;Cardiovascular disease;Folding, sorting and degradation;Endocrine and metabolic disease;Cell growth and death"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko05202//Transcriptional misregulation in cancer;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04210//Apoptosis	K04452;K04452;K04452;K04452;K04452;K04452;K04452;K04452;K04452;K04452;K04452	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005829//cytosol;GO:0032993//protein-DNA complex;GO:0036488//CHOP-C/EBP complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990617//CHOP-ATF4 complex;GO:1990622//CHOP-ATF3 complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043522//leucine zipper domain binding;GO:0046982//protein heterodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001955//blood vessel maturation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006983//ER overload response;GO:0006986//response to unfolded protein;GO:0007049//cell cycle;GO:0007605//sensory perception of sound;GO:0009611//response to wounding;GO:0009948//anterior/posterior axis specification;GO:0010467//gene expression;GO:0010506//regulation of autophagy;GO:0016055//Wnt signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032689//negative regulation of interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0032713//negative regulation of interleukin-4 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032792//negative regulation of CREB transcription factor activity;GO:0034976//response to endoplasmic reticulum stress;GO:0036119//response to platelet-derived growth factor;GO:0036499//PERK-mediated unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response;GO:0042594//response to starvation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0045454//cell redox homeostasis;GO:0045599//negative regulation of fat cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051898//negative regulation of protein kinase B signaling;GO:0060840//artery development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0072655//establishment of protein localization to mitochondrion;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis;GO:0140467//integrated stress response signaling;GO:1901216//positive regulation of neuron death;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1904738//vascular associated smooth muscle cell migration;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:1990442//intrinsic apoptotic signaling pathway in response to nitrosative stress;GO:1990874//vascular associated smooth muscle cell proliferation;GO:2000016//negative regulation of determination of dorsal identity;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	TF_bZIP
ENSG00000175198	6.445	5.56	6.639	6.032	5.96	5.352	330.72	282.88	247.9	230	250	194	PCCA	propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K01965;K01965;K01965;K01965;K01965	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1902494//catalytic complex	GO:0000166//nucleotide binding;GO:0004658//propionyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0016874//ligase activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0009081//branched-chain amino acid metabolic process;GO:0016042//lipid catabolic process;GO:0019626//short-chain fatty acid catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0043603//cellular amide metabolic process;GO:0044281//small molecule metabolic process	--
ENSG00000175202	0	0	0	0	0	0	0	0	0	0	0	0	HIGD2B	HIG1 hypoxia inducible domain family member 2B [Source:HGNC Symbol;Acc:HGNC:26984]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0097250//mitochondrial respirasome assembly	--
ENSG00000175203	76.374	77.884	75.961	80.056	73.191	73.089	1989	1957	1467	1471	1551	1292	DCTN2	dynactin subunit 2 [Source:HGNC Symbol;Acc:HGNC:2712]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10424;K10424;K10424;K10424;K10424	GO:0000776//kinetochore;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030286//dynein complex;GO:0030426//growth cone;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030507//spectrin binding;GO:0042802//identical protein binding	GO:0007017//microtubule-based process;GO:0007052//mitotic spindle organization;GO:0007080//mitotic metaphase plate congression;GO:0032402//melanosome transport;GO:0071539//protein localization to centrosome	--
ENSG00000175206	0	0	0	0.358	0	0	0	0	0	4	0	0	NPPA	natriuretic peptide A [Source:HGNC Symbol;Acc:HGNC:7939]	Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Signal transduction;Signal transduction;Endocrine system;Circulatory system;Signal transduction;Infectious disease: parasitic;Endocrine system;Endocrine system;Endocrine system	ko04714//Thermogenesis;ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04066//HIF-1 signaling pathway;ko05143//African trypanosomiasis;ko04925//Aldosterone synthesis and secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K12334;K12334;K12334;K12334;K12334;K12334;K12334;K12334;K12334;K12334	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0051427//hormone receptor binding;GO:0071855//neuropeptide receptor binding	GO:0003085//negative regulation of systemic arterial blood pressure;GO:0003161//cardiac conduction system development;GO:0003180//aortic valve morphogenesis;GO:0006182//cGMP biosynthetic process;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007565//female pregnancy;GO:0008217//regulation of blood pressure;GO:0010460//positive regulation of heart rate;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0019934//cGMP-mediated signaling;GO:0035994//response to muscle stretch;GO:0036376//sodium ion export across plasma membrane;GO:0042311//vasodilation;GO:0043508//negative regulation of JUN kinase activity;GO:0045776//negative regulation of blood pressure;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0060452//positive regulation of cardiac muscle contraction;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1902261//positive regulation of delayed rectifier potassium channel activity;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:1903766//positive regulation of potassium ion export across plasma membrane	--
ENSG00000175213	5.451	5.229	5.74	5.314	5.735	6.956	252	243	196	182	224	234	ZNF408	zinc finger protein 408 [Source:HGNC Symbol;Acc:HGNC:20041]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000175215	48.068	48.254	53.975	59.364	55.101	57.763	3899	3974	3284	3550	3971	3465	CTDSP2	CTD small phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:17077]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000175216	16.328	13.564	11.931	8.308	10.047	12.542	2403	2011	1296	891	1225	1193	CKAP5	cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0035371//microtubule plus-end"	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043021//ribonucleoprotein complex binding;GO:0045296//cadherin binding;GO:0051010//microtubule plus-end binding;GO:0061863//microtubule plus end polymerase	GO:0007019//microtubule depolymerization;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007052//mitotic spindle organization;GO:0007098//centrosome cycle;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0046785//microtubule polymerization;GO:0050658//RNA transport;GO:0051298//centrosome duplication;GO:0051301//cell division;GO:0090063//positive regulation of microtubule nucleation	--
ENSG00000175220	56.712	65.176	56.586	62.146	66.784	53.448	3894	4509.21	2862	3155.97	3816	2631	ARHGAP1	Rho GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:673]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097443//sorting endosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0031267//small GTPase binding;GO:0045296//cadherin binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0016197//endosomal transport;GO:0033572//transferrin transport;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:2001136//negative regulation of endocytic recycling	--
ENSG00000175221	21.728	23.496	27.825	25.161	27.65	24.642	1480	1577	1305	1258	1498	1213	MED16	mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15159	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003713//transcription coactivator activity;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000175224	51.736	54.979	49.139	45.052	51.573	49.174	3016.3	3266.9	2252.73	2211	2544	2226	ATG13	autophagy related 13 [Source:HGNC Symbol;Acc:HGNC:29091]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Aging;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04211//Longevity regulating pathway;ko04136//Autophagy - other	K08331;K08331;K08331;K08331;K08331;K08331;K08331;K08331	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane;GO:1990316//Atg1/ULK1 kinase complex	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0000045//autophagosome assembly;GO:0000423//mitophagy;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0008285//negative regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0034497//protein localization to phagophore assembly site;GO:0034727//piecemeal microautophagy of the nucleus;GO:0046777//protein autophosphorylation;GO:0098780//response to mitochondrial depolarisation;GO:1903059//regulation of protein lipidation;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000175229	5.451	6.225	4.881	6.187	8.308	6.924	321	347	205	279	381	300	GAL3ST3	galactose-3-O-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:24144]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0001733//galactosylceramide sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0050694//galactose 3-O-sulfotransferase activity;GO:0050698//proteoglycan sulfotransferase activity	GO:0005996//monosaccharide metabolic process;GO:0006790//sulfur compound metabolic process;GO:0009247//glycolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0030309//poly-N-acetyllactosamine metabolic process	--
ENSG00000175262	0	0	0	0	0	0.029	0	0	0	0	0	1	C1orf127	chromosome 1 open reading frame 127 [Source:HGNC Symbol;Acc:HGNC:26730]	-	-	-	-	-	-	-	--
ENSG00000175264	0.049	0.111	0.167	0.1	0.029	0.119	4	9	10	6	2	7	CHST1	carbohydrate sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:1969]	Metabolism	Glycan biosynthesis and metabolism	ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K01022	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0045130//keratan sulfotransferase activity	GO:0005975//carbohydrate metabolic process;GO:0005976//polysaccharide metabolic process;GO:0006012//galactose metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0018146//keratan sulfate biosynthetic process;GO:0042339//keratan sulfate metabolic process	--
ENSG00000175265	3.503	2.853	3.159	4.852	4.917	4.591	385.01	314.12	256.19	392.64	451.71	362.87	GOLGA8A	golgin A8 family member A [Source:HGNC Symbol;Acc:HGNC:31972]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000175267	0.343	0.12	0.114	0.229	0.027	0.145	6	10	8	3	2	3	VWA3A	von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000175274	9.681	9.75	9.33	9.102	9.036	9.27	578	518	350	420	476	383	TP53I11	tumor protein p53 inducible protein 11 [Source:HGNC Symbol;Acc:HGNC:16842]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0008285//negative regulation of cell population proliferation	--
ENSG00000175279	9.743	11.022	9.028	8.924	6.896	9.126	179.68	205.99	124.19	123.78	107	124.08	CENPS	centromere protein S [Source:HGNC Symbol;Acc:HGNC:23163]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K11511	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex"	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031297//replication fork processing;GO:0031398//positive regulation of protein ubiquitination;GO:0036297//interstrand cross-link repair;GO:0051301//cell division;GO:0051382//kinetochore assembly	Others
ENSG00000175283	14.226	13.945	16.965	15.377	14.61	16.102	612	603	539	490	531	504	DOLK	dolichol kinase [Source:HGNC Symbol;Acc:HGNC:23406]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K00902;K00902	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0004168//dolichol kinase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006489//dolichyl diphosphate biosynthetic process;GO:0006629//lipid metabolic process;GO:0016310//phosphorylation;GO:0043048//dolichyl monophosphate biosynthetic process	--
ENSG00000175287	25.446	31.168	29.712	34.388	30.684	25.867	652	796	578	620	667	488	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23396]	-	-	-	-	-	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	-	--
ENSG00000175294	0	0.019	0	0	0	0	0	1	0	0	0	0	CATSPER1	cation channel sperm associated 1 [Source:HGNC Symbol;Acc:HGNC:17116]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0070588//calcium ion transmembrane transport	--
ENSG00000175305	0	0.134	0.048	0.027	0	0.124	0	5.99	1	1.09	0	6.23	CCNE2	cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Infectious disease: viral;Cell growth and death;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Cell growth and death;Cell growth and death;Cancer: specific types;Cancer: specific types;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05206//MicroRNAs in cancer;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04934//Cushing syndrome;ko05226//Gastric cancer;ko05162//Measles;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko05215//Prostate cancer;ko05222//Small cell lung cancer;ko04115//p53 signaling pathway	K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626;K06626	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0097134//cyclin E1-CDK2 complex;GO:0097135//cyclin E2-CDK2 complex	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019901//protein kinase binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000723//telomere maintenance;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:0007129//homologous chromosome pairing at meiosis;GO:0032880//regulation of protein localization;GO:0044772//mitotic cell cycle phase transition;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle	--
ENSG00000175309	6.792	8.741	7.927	8.344	10.035	10.559	269	340	248	222	298	280	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase [Source:HGNC Symbol;Acc:HGNC:28249]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K18202;K18202	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	-	--
ENSG00000175311	0	0	0	0	0	0	0	0	0	0	0	0	ANKS4B	ankyrin repeat and sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:HGNC:26795]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0034622//cellular protein-containing complex assembly;GO:0034976//response to endoplasmic reticulum stress;GO:1904106//protein localization to microvillus;GO:1904970//brush border assembly	--
ENSG00000175315	2.606	2.512	0.882	1.979	0.868	1.343	32	31	8	18	9	12	CST6	cystatin E/M [Source:HGNC Symbol;Acc:HGNC:2478]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0008544//epidermis development;GO:0009653//anatomical structure morphogenesis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000175318	0.969	0.628	0.576	0.803	0.509	0.403	54	43	29	28	26	17	GRAMD2A	GRAM domain containing 2A [Source:HGNC Symbol;Acc:HGNC:27287]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044232//organelle membrane contact site	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding"	GO:0061817//endoplasmic reticulum-plasma membrane tethering;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000175322	0.461	0.751	0.392	0.642	0.29	0.379	43	60	27	33	20	22	ZNF519	zinc finger protein 519 [Source:HGNC Symbol;Acc:HGNC:30574]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000175324	18.637	18.23	20.539	17.168	13.708	19.132	353	347	286	240	219	264	LSM1	"LSM1 homolog, mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20472]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12620	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990726//Lsm1-7-Pat1 complex	GO:0000339//RNA cap binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0000375//RNA splicing, via transesterification reactions;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0016070//RNA metabolic process;GO:0019827//stem cell population maintenance;GO:0045665//negative regulation of neuron differentiation;GO:0071044//histone mRNA catabolic process"	--
ENSG00000175325	0	0	0	0	0	0	0	0	0	0	0	0	PROP1	PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0009887//animal organ morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0016477//cell migration;GO:0021979//hypothalamus cell differentiation;GO:0021983//pituitary gland development;GO:0021984//adenohypophysis development;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048732//gland development;GO:0048850//hypophysis morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060126//somatotropin secreting cell differentiation"	Homeobox
ENSG00000175329	0	0	0	0	0	0	0	0	0	0	0	0	ISX	intestine specific homeobox [Source:HGNC Symbol;Acc:HGNC:28084]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0048484//enteric nervous system development"	Homeobox
ENSG00000175334	74.73	79.257	89.415	86.562	82.695	82.565	1165	1256	1038	1006	1094	947	BANF1	BAF nuclear assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:17397]	-	-	-	-	GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0097726//LEM domain binding	GO:0006325//chromatin organization;GO:0007059//chromosome segregation;GO:0007084//mitotic nuclear membrane reassembly;GO:0009615//response to virus;GO:0015074//DNA integration;GO:0030261//chromosome condensation;GO:0032480//negative regulation of type I interferon production;GO:0045071//negative regulation of viral genome replication;GO:0045824//negative regulation of innate immune response	--
ENSG00000175336	0	0	0	0	0	0	0	0	0	0	0	0	APOF	apolipoprotein F [Source:HGNC Symbol;Acc:HGNC:615]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0034362//low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle	GO:0005102//signaling receptor binding;GO:0005319//lipid transporter activity;GO:0015485//cholesterol binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process	--
ENSG00000175344	1.095	1.137	1.781	1.552	1.864	1.15	93.19	58.32	72.89	83.48	72.25	73.4	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Cancer: overview;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko04725//Cholinergic synapse;ko05033//Nicotine addiction	K04809;K04809;K04809;K04809;K04809;K04809;K04809	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0044853//plasma membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015464//acetylcholine receptor activity;GO:0015643//toxic substance binding;GO:0017081//chloride channel regulator activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity;GO:0042166//acetylcholine binding;GO:0042803//protein homodimerization activity	"GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0007611//learning or memory;GO:0007613//memory;GO:0007614//short-term memory;GO:0008284//positive regulation of cell population proliferation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034220//ion transmembrane transport;GO:0035094//response to nicotine;GO:0042391//regulation of membrane potential;GO:0043410//positive regulation of MAPK cascade;GO:0045766//positive regulation of angiogenesis;GO:0050808//synapse organization;GO:0050877//nervous system process;GO:0050890//cognition;GO:0050893//sensory processing;GO:0051247//positive regulation of protein metabolic process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport;GO:0095500//acetylcholine receptor signaling pathway;GO:0097061//dendritic spine organization;GO:0098815//modulation of excitatory postsynaptic potential;GO:0140059//dendrite arborization;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1901214//regulation of neuron death;GO:1902004//positive regulation of amyloid-beta formation;GO:1902430//negative regulation of amyloid-beta formation;GO:1902991//regulation of amyloid precursor protein catabolic process;GO:1904645//response to amyloid-beta;GO:1905144//response to acetylcholine;GO:1905906//regulation of amyloid fibril formation;GO:1905920//positive regulation of CoA-transferase activity;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000175348	30.399	30.189	32.135	33.135	33.147	33.719	1123	1112	874	914	1040	922	TMEM9B	TMEM9 domain family member B [Source:HGNC Symbol;Acc:HGNC:1168]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane	GO:0005515//protein binding	GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000175352	1.33	0.72	0.575	0.329	0.288	0.335	39	37	11	19	19	19	NRIP3	nuclear receptor interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:1167]	-	-	-	-	-	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding	GO:0006508//proteolysis	--
ENSG00000175354	7.942	5.937	5.127	5.108	4.984	6.803	316	240	157	135	162	191	PTPN2	protein tyrosine phosphatase non-receptor type 2 [Source:HGNC Symbol;Acc:HGNC:9650]	Environmental Information Processing	Signal transduction	ko04630//JAK-STAT signaling pathway	K18026	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0019905//syntaxin binding;GO:0030971//receptor tyrosine kinase binding;GO:0097677//STAT family protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006470//protein dephosphorylation;GO:0008285//negative regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010888//negative regulation of lipid storage;GO:0016311//dephosphorylation;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0030218//erythrocyte differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042593//glucose homeostasis;GO:0045650//negative regulation of macrophage differentiation;GO:0045722//positive regulation of gluconeogenesis;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050922//negative regulation of chemotaxis;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0070104//negative regulation of interleukin-6-mediated signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1902202//regulation of hepatocyte growth factor receptor signaling pathway;GO:1902206//negative regulation of interleukin-2-mediated signaling pathway;GO:1902215//negative regulation of interleukin-4-mediated signaling pathway;GO:1902227//negative regulation of macrophage colony-stimulating factor signaling pathway;GO:1902233//negative regulation of positive thymic T cell selection;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway	--
ENSG00000175356	0.163	0.155	0.123	0.422	0.256	0.098	12	13	7	6	15	5	SCUBE2	"signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]"	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K24706	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0097108//hedgehog family protein binding	GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0007165//signal transduction;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045880//positive regulation of smoothened signaling pathway;GO:1902732//positive regulation of chondrocyte proliferation	--
ENSG00000175376	9.596	8.679	12.481	11.447	11.139	12.724	338	292	286	261	372	278	EIF1AD	eukaryotic translation initiation factor 1A domain containing [Source:HGNC Symbol;Acc:HGNC:28147]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000175387	34.269	38.626	28.969	30.679	29.615	37.214	1649.14	1604.38	1052.22	1016	1164	1165.13	SMAD2	SMAD family member 2 [Source:HGNC Symbol;Acc:HGNC:6768]	Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: specific types;Cell growth and death;Signal transduction;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Endocrine system;Cell growth and death;Immune system;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Immune disease	ko05200//Pathways in cancer;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko05225//Hepatocellular carcinoma;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04371//Apelin signaling pathway;ko04926//Relaxin signaling pathway;ko04110//Cell cycle;ko04659//Th17 cell differentiation;ko05142//Chagas disease;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04350//TGF-beta signaling pathway;ko05210//Colorectal cancer;ko05212//Pancreatic cancer;ko05321//Inflammatory bowel disease	K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500;K04500	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032444//activin responsive factor complex;GO:0032991//protein-containing complex;GO:0071141//SMAD protein complex;GO:0071142//homomeric SMAD protein complex;GO:0071144//heteromeric SMAD protein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0042802//identical protein binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0048156//tau protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070410//co-SMAD binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding;GO:0097718//disordered domain specific binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0001657//ureteric bud development;GO:0001701//in utero embryonic development;GO:0001706//endoderm formation;GO:0001707//mesoderm formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007182//common-partner SMAD protein phosphorylation;GO:0007183//SMAD protein complex assembly;GO:0007352//zygotic specification of dorsal/ventral axis;GO:0007369//gastrulation;GO:0007389//pattern specification process;GO:0007492//endoderm development;GO:0007507//heart development;GO:0008285//negative regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0009749//response to glucose;GO:0009791//post-embryonic development;GO:0009880//embryonic pattern specification;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030325//adrenal gland development;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0031016//pancreas development;GO:0031053//primary miRNA processing;GO:0032924//activin receptor signaling pathway;GO:0035265//organ growth;GO:0035556//intracellular signal transduction;GO:0038092//nodal signaling pathway;GO:0042060//wound healing;GO:0045165//cell fate commitment;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048340//paraxial mesoderm morphogenesis;GO:0048589//developmental growth;GO:0048617//embryonic foregut morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0051098//regulation of binding;GO:0060039//pericardium development;GO:0060395//SMAD protein signal transduction;GO:0062009//secondary palate development;GO:0070723//response to cholesterol;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0090287//regulation of cellular response to growth factor stimulus;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry"	MH1
ENSG00000175390	137.337	132.763	132.764	142.743	133.135	116.109	3984	3726	2738	2854	3108	2461	EIF3F	eukaryotic translation initiation factor 3 subunit F [Source:HGNC Symbol;Acc:HGNC:3275]	-	-	-	-	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m"	GO:0003743//translation initiation factor activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031369//translation initiation factor binding;GO:0042802//identical protein binding;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0075522//IRES-dependent viral translational initiation	--
ENSG00000175395	2.044	1.282	1.494	0.972	1.374	0.973	176	111	95	62	100	61	ZNF25	zinc finger protein 25 [Source:HGNC Symbol;Acc:HGNC:13043]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000175398	0	0	0	0	0	0	0	0	0	0	0	0	OR10P1	olfactory receptor family 10 subfamily P member 1 [Source:HGNC Symbol;Acc:HGNC:15378]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000175414	6.625	5.729	8.405	7.292	5.656	6.212	1334.03	1293	1092	932	1073	1015	ARL10	ADP ribosylation factor like GTPase 10 [Source:HGNC Symbol;Acc:HGNC:22042]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	-	--
ENSG00000175416	35.347	41.201	39.134	45.861	45.834	40.533	798	933	652	766	875	664	CLTB	clathrin light chain B [Source:HGNC Symbol;Acc:HGNC:2091]	Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Transport and catabolism;Infectious disease: bacterial;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04142//Lysosome;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K04645;K04645;K04645;K04645;K04645;K04645	GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030118//clathrin coat;GO:0030125//clathrin vesicle coat;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit;GO:0030659//cytoplasmic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0045334//clathrin-coated endocytic vesicle;GO:0060170//ciliary membrane;GO:0098835//presynaptic endocytic zone membrane;GO:0099631//postsynaptic endocytic zone cytoplasmic component	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0032050//clathrin heavy chain binding;GO:0042277//peptide binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0048268//clathrin coat assembly;GO:0072583//clathrin-dependent endocytosis	--
ENSG00000175426	0	0	0	0.032	0	0.03	0	0	0	2	0	1	PCSK1	proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743]	-	-	-	-	GO:0005615//extracellular space;GO:0005791//rough endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0034774//secretory granule lumen;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0048471//perinuclear region of cytoplasm	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0007267//cell-cell signaling;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010035//response to inorganic substance;GO:0010157//response to chlorate;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0016486//peptide hormone processing;GO:0016540//protein autoprocessing;GO:0021983//pituitary gland development;GO:0022008//neurogenesis;GO:0031016//pancreas development;GO:0031667//response to nutrient levels;GO:0032496//response to lipopolysaccharide;GO:0043043//peptide biosynthetic process;GO:0043278//response to morphine;GO:0043434//response to peptide hormone;GO:0048678//response to axon injury;GO:0050714//positive regulation of protein secretion;GO:0051384//response to glucocorticoid;GO:0051592//response to calcium ion;GO:0070542//response to fatty acid;GO:0070555//response to interleukin-1	--
ENSG00000175445	3.888	3.707	4.849	7.635	6.619	4.361	189	202	129	209	212	123	LPL	lipoprotein lipase [Source:HGNC Symbol;Acc:HGNC:6677]	Human Diseases;Organismal Systems;Metabolism;Organismal Systems	Neurodegenerative disease;Endocrine system;Lipid metabolism;Digestive system	ko05010//Alzheimer disease;ko03320//PPAR signaling pathway;ko00561//Glycerolipid metabolism;ko04979//Cholesterol metabolism	K01059;K01059;K01059;K01059	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0034361//very-low-density lipoprotein particle;GO:0042627//chylomicron;GO:1902494//catalytic complex	GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity;GO:0004806//triglyceride lipase activity;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008970//phospholipase A1 activity;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0017129//triglyceride binding;GO:0034185//apolipoprotein binding;GO:0042803//protein homodimerization activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0043495//protein-membrane adaptor activity;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity;GO:0071813//lipoprotein particle binding	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006641//triglyceride metabolic process;GO:0006644//phospholipid metabolic process;GO:0009409//response to cold;GO:0009410//response to xenobiotic stimulus;GO:0009617//response to bacterium;GO:0009749//response to glucose;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010884//positive regulation of lipid storage;GO:0010886//positive regulation of cholesterol storage;GO:0010890//positive regulation of sequestering of triglyceride;GO:0016042//lipid catabolic process;GO:0019432//triglyceride biosynthetic process;GO:0019433//triglyceride catabolic process;GO:0031670//cellular response to nutrient;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034371//chylomicron remodeling;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0042632//cholesterol homeostasis;GO:0045600//positive regulation of fat cell differentiation;GO:0050729//positive regulation of inflammatory response;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0070328//triglyceride homeostasis;GO:0071398//cellular response to fatty acid;GO:1900077//negative regulation of cellular response to insulin stimulus;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000175449	1.112	1.147	1.231	1.062	1.212	0.651	34	32	27	15	25	11	RFESD	Rieske Fe-S domain containing [Source:HGNC Symbol;Acc:HGNC:29587]	-	-	-	-	-	"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	-	--
ENSG00000175455	8.483	5.694	5.725	5.169	7.059	7.309	733	458	374	294	450	437	CCDC14	coiled-coil domain containing 14 [Source:HGNC Symbol;Acc:HGNC:25766]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0021762//substantia nigra development;GO:0071539//protein localization to centrosome	--
ENSG00000175463	0.064	0	0.044	0.261	0.229	0.044	2	0	1	6	6	1	TBC1D10C	TBC1 domain family member 10C [Source:HGNC Symbol;Acc:HGNC:24702]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031527//filopodium membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding	"GO:0042147//retrograde transport, endosome to Golgi;GO:0050869//negative regulation of B cell activation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0090630//activation of GTPase activity"	--
ENSG00000175467	13.947	15.673	15.562	17.127	16.962	15.07	1029	1135	848	936	1022	809	SART1	"spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP [Source:HGNC Symbol;Acc:HGNC:10538]"	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11984	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0000481//maturation of 5S rRNA;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045292//mRNA cis splicing, via spliceosome;GO:0045585//positive regulation of cytotoxic T cell differentiation"	--
ENSG00000175470	12.322	13.097	13.655	13.197	13.474	14.381	691	695	535	521	603	533	PPP2R2D	protein phosphatase 2 regulatory subunit Bdelta [Source:HGNC Symbol;Acc:HGNC:23732]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway	K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354	GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0010458//exit from mitosis;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0070262//peptidyl-serine dephosphorylation	--
ENSG00000175471	4.574	4.357	4.285	5.36	3.402	4.71	281	249	198	139	168	177	MCTP1	multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183]	-	-	-	-	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0055037//recycling endosome	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0019722//calcium-mediated signaling;GO:0030336//negative regulation of cell migration;GO:0045806//negative regulation of endocytosis;GO:0046928//regulation of neurotransmitter secretion;GO:0048168//regulation of neuronal synaptic plasticity;GO:1902883//negative regulation of response to oxidative stress	--
ENSG00000175482	6.142	9.669	9.141	9.672	11.255	8.177	134.51	178.38	142.39	149.33	177.72	121.42	POLD4	"DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K03505;K03505;K03505;K03505;K03505	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043625//delta DNA polymerase complex	GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000175485	0	0	0	0	0	0	0	0	0	0	0	0	OR52W1	olfactory receptor family 52 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:15239]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000175489	0.05	0.175	0.068	0.027	0	0.034	2	7	2	1	0	1	LRRC25	leucine rich repeat containing 25 [Source:HGNC Symbol;Acc:HGNC:29806]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000175497	5.378	5.556	3.235	5.249	5.445	5.895	368	365	163	274	288	290	DPP10	dipeptidyl peptidase like 10 [Source:HGNC Symbol;Acc:HGNC:20823]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008236//serine-type peptidase activity;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding	GO:0006508//proteolysis;GO:0072659//protein localization to plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000175505	0.629	0.45	0.345	0.897	0.803	0.427	18	16	9	20	24	11	CLCF1	cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05421	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0097058//CRLF-CLCF1 complex;GO:0097059//CNTFR-CLCF1 complex	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0002639//positive regulation of immunoglobulin production;GO:0007166//cell surface receptor signaling pathway;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043524//negative regulation of neuron apoptotic process;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0048711//positive regulation of astrocyte differentiation	--
ENSG00000175513	0	0	0	0	0	0	0	0	0	0	0	0	TSGA10IP	testis specific 10 interacting protein [Source:HGNC Symbol;Acc:HGNC:26555]	-	-	-	-	GO:0005929//cilium;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body	GO:0005515//protein binding	GO:0044782//cilium organization	--
ENSG00000175514	0	0	0	0	0	0	0	0	0	0	0	0	GPR152	G protein-coupled receptor 152 [Source:HGNC Symbol;Acc:HGNC:23622]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000175518	0.104	0.042	0.091	0.113	0.027	0.093	5	2	3	4	1	3	UBQLNL	ubiquilin like [Source:HGNC Symbol;Acc:HGNC:28294]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0006511//ubiquitin-dependent protein catabolic process	--
ENSG00000175520	0	0	0	0	0	0	0	0	0	0	0	0	UBQLN3	ubiquilin 3 [Source:HGNC Symbol;Acc:HGNC:12510]	Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Folding, sorting and degradation"	ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum	K04523;K04523	GO:0005829//cytosol	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033554//cellular response to stress	--
ENSG00000175535	0	0.032	0	0	0	0	0	1	0	0	0	0	PNLIP	pancreatic lipase [Source:HGNC Symbol;Acc:HGNC:9155]	Metabolism;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems	Global and overview maps;Digestive system;Lipid metabolism;Digestive system;Digestive system	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption;ko04977//Vitamin digestion and absorption	K14073;K14073;K14073;K14073;K14073	GO:0005576//extracellular region;GO:0005615//extracellular space	"GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047376//all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0052689//carboxylic ester hydrolase activity"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0030299//intestinal cholesterol absorption;GO:0042572//retinol metabolic process;GO:0061365//positive regulation of triglyceride lipase activity	--
ENSG00000175536	1.129	0.946	2.257	1.369	0.832	1.948	42	46	44	46	34	47	LIPT2	lipoyl(octanoyl) transferase 2 [Source:HGNC Symbol;Acc:HGNC:37216]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00785//Lipoic acid metabolism	K23735;K23735	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0016415//octanoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016874//ligase activity;GO:0033819//lipoyl(octanoyl) transferase activity;GO:0102555//octanoyl transferase activity (acting on glycine-cleavage complex H protein)	GO:0006464//cellular protein modification process;GO:0009249//protein lipoylation;GO:0019752//carboxylic acid metabolic process;GO:2000376//positive regulation of oxygen metabolic process	--
ENSG00000175538	2.869	2.365	3.585	2.962	2.368	4.454	142	142	117	116	118	118	KCNE3	potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K04897	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031982//vesicle;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:1990794//basolateral part of cell	GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0030644//cellular chloride ion homeostasis;GO:0034765//regulation of ion transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086011//membrane repolarization during action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:1903765//negative regulation of potassium ion export across plasma membrane;GO:1903817//negative regulation of voltage-gated potassium channel activity;GO:1905025//negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential	--
ENSG00000175544	0	0	0	0	0	0	0	0	0	0	0	0	CABP4	calcium binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1386]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0098793//presynapse	GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0008594//photoreceptor cell morphogenesis;GO:0046549//retinal cone cell development;GO:0060040//retinal bipolar neuron differentiation	--
ENSG00000175548	3.173	2.342	1.863	2.266	3.106	3.311	434	300	244.58	219.52	224	253	ALG10B	"ALG10 alpha-1,2-glucosyltransferase B [Source:HGNC Symbol;Acc:HGNC:31088]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K03850;K03850	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0106073//dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0060050//positive regulation of protein glycosylation;GO:1901980//positive regulation of inward rectifier potassium channel activity	--
ENSG00000175550	33.052	32.07	34.24	34.729	29.887	30.048	562	548	429	437	430	371	DRAP1	DR1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:3019]	-	-	-	-	GO:0005634//nucleus;GO:0017054//negative cofactor 2 complex;GO:0090575//RNA polymerase II transcription regulator complex	GO:0001046//core promoter sequence-specific DNA binding;GO:0001091//RNA polymerase II general transcription initiation factor binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000175556	0.162	0.206	0.424	0.022	0.134	0.138	8	9	13	1	7	5	LONRF3	LON peptidase N-terminal domain and ring finger 3 [Source:HGNC Symbol;Acc:HGNC:21152]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000175564	0.042	0.373	0.172	0.143	0.176	0.152	2	16	6	5	4	5	UCP3	uncoupling protein 3 [Source:HGNC Symbol;Acc:HGNC:12519]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005215//transporter activity;GO:0005515//protein binding;GO:0017077//oxidative phosphorylation uncoupler activity	GO:0000303//response to superoxide;GO:0001666//response to hypoxia;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006839//mitochondrial transport;GO:0007568//aging;GO:0007584//response to nutrient;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009409//response to cold;GO:0014823//response to activity;GO:0032868//response to insulin;GO:0032870//cellular response to hormone stimulus;GO:0048545//response to steroid hormone;GO:0051384//response to glucocorticoid;GO:1902600//proton transmembrane transport;GO:1990542//mitochondrial transmembrane transport;GO:1990845//adaptive thermogenesis	--
ENSG00000175567	41.613	45.502	40.302	30.308	35.555	27.891	1419	1559	1015	763	1000	692	UCP2	uncoupling protein 2 [Source:HGNC Symbol;Acc:HGNC:12518]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0017077//oxidative phosphorylation uncoupler activity	GO:0000303//response to superoxide;GO:0001666//response to hypoxia;GO:0006839//mitochondrial transport;GO:0007565//female pregnancy;GO:0007568//aging;GO:0009409//response to cold;GO:0009749//response to glucose;GO:0010942//positive regulation of cell death;GO:0032869//cellular response to insulin stimulus;GO:0032870//cellular response to hormone stimulus;GO:0034198//cellular response to amino acid starvation;GO:0043066//negative regulation of apoptotic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070542//response to fatty acid;GO:0071333//cellular response to glucose stimulus;GO:0097421//liver regeneration;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1902600//proton transmembrane transport;GO:1990542//mitochondrial transmembrane transport;GO:1990845//adaptive thermogenesis	--
ENSG00000175573	16.386	18.412	18.784	20.74	18.705	18.426	530	599	449	496	511	433	C11orf68	chromosome 11 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:28801]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000175575	13.779	15.062	14.912	12.58	12.183	12.347	380	401	300	268	282	254	PAAF1	proteasomal ATPase associated factor 1 [Source:HGNC Symbol;Acc:HGNC:25687]	-	-	-	-	GO:0000502//proteasome complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000175581	9.862	9.235	9.031	10.43	10.207	9.695	265	225	164	199	208	170	MRPL48	mitochondrial ribosomal protein L48 [Source:HGNC Symbol;Acc:HGNC:16653]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0005515//protein binding	GO:0032543//mitochondrial translation	--
ENSG00000175582	66.164	58.062	60.198	56.255	56.334	57.288	4033	3654.99	2769.99	2528.99	2776.99	2506	RAB6A	"RAB6A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9786]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0070062//extracellular exosome;GO:0070381//endosome to plasma membrane transport vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0031489//myosin V binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0018125//peptidyl-cysteine methylation;GO:0019882//antigen processing and presentation;GO:0034067//protein localization to Golgi apparatus;GO:0034498//early endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0072385//minus-end-directed organelle transport along microtubule"	--
ENSG00000175591	1.264	1.681	0.926	0.857	0.83	0.826	184	210	100	84	125	95	P2RY2	purinergic receptor P2Y2 [Source:HGNC Symbol;Acc:HGNC:8541]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04750//Inflammatory mediator regulation of TRP channels	K04269;K04269	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0006873//cellular ion homeostasis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0070257//positive regulation of mucus secretion;GO:0071318//cellular response to ATP;GO:0097746//blood vessel diameter maintenance	--
ENSG00000175592	0.503	0.197	0.211	0.284	0.04	0.078	14	7	4	7	1	2	FOSL1	"FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718]"	Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Infectious disease: viral;Signal transduction;Development and regeneration;Immune system	ko05166//Human T-cell leukemia virus 1 infection;ko04310//Wnt signaling pathway;ko04380//Osteoclast differentiation;ko04657//IL-17 signaling pathway	K04502;K04502;K04502;K04502	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006935//chemotaxis;GO:0006968//cellular defense response;GO:0007296//vitellogenesis;GO:0007565//female pregnancy;GO:0007612//learning;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009615//response to virus;GO:0009629//response to gravity;GO:0014070//response to organic cyclic compound;GO:0031668//cellular response to extracellular stimulus;GO:0032570//response to progesterone;GO:0034097//response to cytokine;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0045787//positive regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051412//response to corticosterone;GO:0051591//response to cAMP;GO:0060674//placenta blood vessel development;GO:0140467//integrated stress response signaling;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:2000144//positive regulation of DNA-templated transcription, initiation"	TF_bZIP
ENSG00000175595	3.538	3.282	3.324	2.781	2.887	3.513	485	454	339	288	329	342	ERCC4	"ERCC excision repair 4, endonuclease catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3436]"	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair	K10848;K10848	"GO:0000109//nucleotide-excision repair complex;GO:0000110//nucleotide-excision repair factor 1 complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070522//ERCC4-ERCC1 complex"	GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0001094//TFIID-class transcription factor complex binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0047485//protein N-terminus binding;GO:1990599//3' overhang single-stranded DNA endodeoxyribonuclease activity;GO:1990841//promoter-specific chromatin binding	"GO:0000712//resolution of meiotic recombination intermediates;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0009411//response to UV;GO:0009650//UV protection;GO:0010506//regulation of autophagy;GO:0032205//negative regulation of telomere maintenance;GO:0033554//cellular response to stress;GO:0033683//nucleotide-excision repair, DNA incision;GO:0034644//cellular response to UV;GO:0061819//telomeric DNA-containing double minutes formation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1901255//nucleotide-excision repair involved in interstrand cross-link repair;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1905765//negative regulation of protection from non-homologous end joining at telomere;GO:1905768//negative regulation of double-stranded telomeric DNA binding"	--
ENSG00000175600	2.076	2.803	3.341	3.089	3.095	3.568	68	93	80	74	85	83	SUGCT	succinyl-CoA:glutarate-CoA transferase [Source:HGNC Symbol;Acc:HGNC:16001]	-	-	-	-	GO:0005739//mitochondrion	GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0047369//succinate-hydroxymethylglutarate CoA-transferase activity	-	--
ENSG00000175602	19.174	15.59	17.963	20.614	18.073	19.679	383	313	265	305	305	286	CCDC85B	coiled-coil domain containing 85B [Source:HGNC Symbol;Acc:HGNC:24926]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0030054//cell junction	GO:0005515//protein binding;GO:0070097//delta-catenin binding	"GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0040008//regulation of growth;GO:0045599//negative regulation of fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000175606	11.052	10.143	12.107	10.971	10.103	14.71	310	294	250	258	228	309	TMEM70	transmembrane protein 70 [Source:HGNC Symbol;Acc:HGNC:26050]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030061//mitochondrial crista;GO:0032592//integral component of mitochondrial membrane	GO:0005515//protein binding;GO:0140260//mitochondrial proton-transporting ATP synthase complex binding	GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0051259//protein complex oligomerization;GO:0051260//protein homooligomerization	--
ENSG00000175619	0	0	0	0	0	0	0	0	0	0	0	0	OR4B1	olfactory receptor family 4 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:8290]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000175634	26.145	31.025	29.735	32.385	30.703	29.68	886	1044	756	803	892	726	RPS6KB2	ribosomal protein S6 kinase B2 [Source:HGNC Symbol;Acc:HGNC:10437]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Immune system;Cancer: specific types;Signal transduction;Transport and catabolism;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Cancer: overview;Drug resistance: antineoplastic;Cancer: overview;Signal transduction;Aging;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Aging	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05131//Shigellosis;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko05231//Choline metabolism in cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04350//TGF-beta signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species	K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042277//peptide binding;GO:0106310//protein serine kinase activity	GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031929//TOR signaling;GO:0043491//protein kinase B signaling;GO:0045948//positive regulation of translational initiation	--
ENSG00000175643	0.797	1.633	0.915	1.081	0.72	0.836	24	49	20	21	18	18	RMI2	RecQ mediated genome instability 2 [Source:HGNC Symbol;Acc:HGNC:28349]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15365	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0031422//RecQ family helicase-topoisomerase III complex	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0033045//regulation of sister chromatid segregation;GO:0043007//maintenance of rDNA;GO:0071139//resolution of recombination intermediates;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000175646	0	0	0	0	0	0	0	0	0	0	0	0	PRM1	protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006323//DNA packaging;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030261//chromosome condensation	--
ENSG00000175662	10.618	11.186	11.504	12.436	12.173	11.314	1196	1284	913	963	1171	887	TOM1L2	target of myb1 like 2 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11984]	-	-	-	-	GO:0005768//endosome;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030276//clathrin binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding	GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0045839//negative regulation of mitotic nuclear division	--
ENSG00000175664	0	0.119	0	0	0	0	0	2	0	0	0	0	TEX26	testis expressed 26 [Source:HGNC Symbol;Acc:HGNC:28622]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000175691	1.583	1.411	0.864	1.308	1.231	1.039	67	60	27	41	44	32	ZNF77	zinc finger protein 77 [Source:HGNC Symbol;Acc:HGNC:13150]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000175697	2.567	2.716	3.023	1.334	1.92	2.198	232	254	184	92	141	130	GPR156	G protein-coupled receptor 156 [Source:HGNC Symbol;Acc:HGNC:20844]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04617	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0038039//G protein-coupled receptor heterodimeric complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004965//G protein-coupled GABA receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway	--
ENSG00000175699	0	0	0	0	0	0	0	0	0	0	0	0	CCDC197	coiled-coil domain containing 197 [Source:HGNC Symbol;Acc:HGNC:19860]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000175701	8.016	7.724	11.16	11.889	7.723	11.557	71	69	73	78	58	75	MTLN	mitoregulin [Source:HGNC Symbol;Acc:HGNC:27339]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding	GO:0006635//fatty acid beta-oxidation;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0044255//cellular lipid metabolic process;GO:0045333//cellular respiration;GO:0051146//striated muscle cell differentiation;GO:0051284//positive regulation of sequestering of calcium ion;GO:0070328//triglyceride homeostasis	--
ENSG00000175707	0	0.103	0	0	0.062	0	0	4	0	0	2	0	KDF1	keratinocyte differentiation factor 1 [Source:HGNC Symbol;Acc:HGNC:26624]	-	-	-	-	GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0031252//cell leading edge	GO:0005515//protein binding	GO:0003334//keratinocyte development;GO:0010482//regulation of epidermal cell division;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016331//morphogenesis of embryonic epithelium;GO:0030154//cell differentiation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0048589//developmental growth;GO:0060887//limb epidermis development;GO:0061436//establishment of skin barrier;GO:2000647//negative regulation of stem cell proliferation	--
ENSG00000175711	0.568	0.788	0.914	0.666	0.865	0.994	31.62	37.06	40.15	30.56	45.23	37.15	B3GNTL1	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 [Source:HGNC Symbol;Acc:HGNC:21727]"	-	-	-	-	-	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	-	--
ENSG00000175718	0	0	0	0	0	0	0	0	0	0	0	0	RBMXL3	RBMX like 3 [Source:HGNC Symbol;Acc:HGNC:26859]	-	-	-	-	GO:0005689//U12-type spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0017069//snRNA binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000175727	3.436	3.892	3.463	3.248	3.504	3.748	598	553	430	380	474	426	MLXIP	MLX interacting protein [Source:HGNC Symbol;Acc:HGNC:17055]	Human Diseases;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease	ko04932//Non-alcoholic fatty liver disease;ko04931//Insulin resistance	K09113;K09113	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	bHLH
ENSG00000175745	12.792	12.326	13.917	19.118	19.393	19.132	772	710	577	841	893	830	NR2F1	nuclear receptor subfamily 2 group F member 1 [Source:HGNC Symbol;Acc:HGNC:7975]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0010977//negative regulation of neuron projection development;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	RXR-like
ENSG00000175756	52.545	53.21	58.887	70.58	60.362	54.046	850	871	712	854	827	642	AURKAIP1	aurora kinase A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24114]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0032543//mitochondrial translation;GO:0045839//negative regulation of mitotic nuclear division;GO:0045862//positive regulation of proteolysis	--
ENSG00000175764	1.582	2.148	3.342	2.385	2.345	1.835	154	162	156	129	147	104	TTLL11	tubulin tyrosine ligase like 11 [Source:HGNC Symbol;Acc:HGNC:18113]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation;GO:0051013//microtubule severing	--
ENSG00000175766	0	0	0	0	0	0	0	0	0	0	0	0	EIF4E1B	eukaryotic translation initiation factor 4E family member 1B [Source:HGNC Symbol;Acc:HGNC:33179]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Endocrine system;Signal transduction;Aging;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko04150//mTOR signaling pathway;ko04910//Insulin signaling pathway;ko04066//HIF-1 signaling pathway;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K03259;K03259;K03259;K03259;K03259;K03259	GO:0005737//cytoplasm;GO:0005845//mRNA cap binding complex;GO:0016281//eukaryotic translation initiation factor 4F complex	GO:0000340//RNA 7-methylguanosine cap binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006413//translational initiation;GO:0006417//regulation of translation	--
ENSG00000175768	37.398	39.921	39.037	38.495	37.079	36.608	554	591	428	420.5	463	394	TOMM5	translocase of outer mitochondrial membrane 5 [Source:HGNC Symbol;Acc:HGNC:31369]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006626//protein targeting to mitochondrion;GO:0015031//protein transport;GO:0045040//protein insertion into mitochondrial outer membrane	--
ENSG00000175782	4.112	3.731	4.604	4.399	4.229	3.637	348	345	276	268	301	212	SLC35E3	solute carrier family 35 member E3 [Source:HGNC Symbol;Acc:HGNC:20864]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005338//nucleotide-sugar transmembrane transporter activity;GO:0005515//protein binding;GO:0015297//antiporter activity	GO:0015931//nucleobase-containing compound transport;GO:0055085//transmembrane transport;GO:1901264//carbohydrate derivative transport	--
ENSG00000175785	0	0	0	0	0	0	0	0	0	0	0	0	PRIMA1	proline rich membrane anchor 1 [Source:HGNC Symbol;Acc:HGNC:18319]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	-	GO:0042135//neurotransmitter catabolic process	--
ENSG00000175787	0.885	0.814	0.674	1.003	1.098	0.921	45	39	25	37	46	33	ZNF169	zinc finger protein 169 [Source:HGNC Symbol;Acc:HGNC:12957]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000175792	21.041	22.869	20.817	21.67	18.876	21.835	826.53	907.64	606.84	631.63	630.19	628.72	RUVBL1	RuvB like AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:10474]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04499	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031011//Ino80 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0070062//extracellular exosome;GO:0071339//MLL1 complex;GO:0097255//R2TP complex;GO:0101031//chaperone complex;GO:0120293//dynein axonemal particle;GO:1990062//RPAP3/R2TP/prefoldin-like complex;GO:1990904//ribonucleoprotein complex	"GO:0000166//nucleotide binding;GO:0001094//TFIID-class transcription factor complex binding;GO:0003678//DNA helicase activity;GO:0003713//transcription coactivator activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017025//TBP-class protein binding;GO:0043531//ADP binding;GO:0045296//cadherin binding;GO:0051117//ATPase binding"	"GO:0000492//box C/D snoRNP assembly;GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0016573//histone acetylation;GO:0032508//DNA duplex unwinding;GO:0033044//regulation of chromosome organization;GO:0040008//regulation of growth;GO:0042766//nucleosome mobilization;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1904507//positive regulation of telomere maintenance in response to DNA damage;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000175793	0	0.037	0	0	0.044	0	0	1	0	0	1	0	SFN	stratifin [Source:HGNC Symbol;Acc:HGNC:10773]	Cellular Processes;Cellular Processes;Organismal Systems	Cell growth and death;Cell growth and death;Excretory system	ko04110//Cell cycle;ko04115//p53 signaling pathway;ko04960//Aldosterone-regulated sodium reabsorption	K06644;K06644;K06644	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008426//protein kinase C inhibitor activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051219//phosphoprotein binding	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001836//release of cytochrome c from mitochondria;GO:0003334//keratinocyte development;GO:0006469//negative regulation of protein kinase activity;GO:0007165//signal transduction;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010482//regulation of epidermal cell division;GO:0010839//negative regulation of keratinocyte proliferation;GO:0030216//keratinocyte differentiation;GO:0030307//positive regulation of cell growth;GO:0031424//keratinization;GO:0034613//cellular protein localization;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043588//skin development;GO:0045606//positive regulation of epidermal cell differentiation;GO:0046827//positive regulation of protein export from nucleus;GO:0051726//regulation of cell cycle;GO:0061436//establishment of skin barrier	--
ENSG00000175806	9.538	9.434	10.779	10.848	9.743	12.282	298	285	243	252	257	278	MSRA	methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008113//peptide-methionine (S)-S-oxide reductase activity;GO:0016491//oxidoreductase activity;GO:0033744//L-methionine:thioredoxin-disulfide S-oxidoreductase activity;GO:0036456//L-methionine-(S)-S-oxide reductase activity	GO:0006464//cellular protein modification process;GO:0006555//methionine metabolic process;GO:0006979//response to oxidative stress;GO:0030091//protein repair;GO:0034599//cellular response to oxidative stress	--
ENSG00000175809	0	0	0	0	0	0	0	0	0	0	0	0	CBLL2	Cbl proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:26371]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0030155//regulation of cell adhesion	--
ENSG00000175820	0	0	0	0	0	0	0	0	0	0	0	0	CCDC168	coiled-coil domain containing 168 [Source:HGNC Symbol;Acc:HGNC:26851]	-	-	-	-	-	-	-	--
ENSG00000175826	63.705	64.972	66.253	74.068	73.101	75.114	2068	2048	1537	1759	2033	1644	CTDNEP1	CTD nuclear envelope phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:19085]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0071595//Nem1-Spo7 phosphatase complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0006998//nuclear envelope organization;GO:0007077//mitotic nuclear membrane disassembly;GO:0007276//gamete generation;GO:0007498//mesoderm development;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0016311//dephosphorylation;GO:0034504//protein localization to nucleus;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000175832	0.18	0.028	0.151	0.339	0.187	0.072	7	1	4	9	3	1	ETV4	ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15592	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000175854	12.227	11.769	13.178	11.162	11.222	10.165	192	191	164	132	153	118	SWI5	SWI5 homologous recombination repair protein [Source:HGNC Symbol;Acc:HGNC:31412]	-	-	-	-	-	-	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000175857	0	0	0	0	0	0	0	0	0	0	0	0	GAPT	"GRB2 binding adaptor protein, transmembrane [Source:HGNC Symbol;Acc:HGNC:26588]"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	GO:0001782//B cell homeostasis;GO:0002322//B cell proliferation involved in immune response;GO:0042113//B cell activation	--
ENSG00000175866	49.357	56.311	58.035	72.363	63.027	71.441	1555.83	1727.41	1363.5	1633.94	1657.73	1520.94	BAIAP2	BAR/IMD domain containing adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:947]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Infectious disease: bacterial;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes	ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04520//Adherens junction	K05627;K05627;K05627;K05627	"GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030141//secretory granule;GO:0030175//filopodium;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0044306//neuron projection terminus;GO:0060076//excitatory synapse;GO:0061845//neuron projection branch point;GO:0061846//dendritic spine cytoplasm;GO:0070062//extracellular exosome;GO:0097060//synaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol"	GO:0001221//transcription coregulator binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008093//cytoskeletal anchor activity;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0070064//proline-rich region binding;GO:0097110//scaffold protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion	"GO:0007009//plasma membrane organization;GO:0007409//axonogenesis;GO:0007420//brain development;GO:0008286//insulin receptor signaling pathway;GO:0008360//regulation of cell shape;GO:0009617//response to bacterium;GO:0010976//positive regulation of neuron projection development;GO:0016358//dendrite development;GO:0030182//neuron differentiation;GO:0030838//positive regulation of actin filament polymerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0035418//protein localization to synapse;GO:0048167//regulation of synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission;GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0098609//cell-cell adhesion;GO:0099564//modification of synaptic structure, modulating synaptic transmission;GO:1905232//cellular response to L-glutamate;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000175868	0.508	0.071	0	0	0	0.063	11	2	0	0	0	1	CALCB	calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04270//Vascular smooth muscle contraction	K12332;K12332	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0031716//calcitonin receptor binding	GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration	--
ENSG00000175874	0.015	0	0	0.01	0	0	2	0	0	1	0	0	CREG2	cellular repressor of E1A stimulated genes 2 [Source:HGNC Symbol;Acc:HGNC:14272]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus	-	-	--
ENSG00000175877	0	0	0	0	0	0	0	0	0	0	0	0	TMEM270	transmembrane protein 270 [Source:HGNC Symbol;Acc:HGNC:23018]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000175879	0	0	0	0	0	0	0	0	0	0	0	0	HOXD8	homeobox D8 [Source:HGNC Symbol;Acc:HGNC:5139]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008595//anterior/posterior axis specification, embryo;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048705//skeletal system morphogenesis"	Homeobox
ENSG00000175893	2.823	2.314	2.433	2.369	2.209	2.557	534	440	340	332	353	352	ZDHHC21	zinc finger DHHC-type palmitoyltransferase 21 [Source:HGNC Symbol;Acc:HGNC:20750]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0001942//hair follicle development;GO:0003056//regulation of vascular associated smooth muscle contraction;GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0048733//sebaceous gland development;GO:0050999//regulation of nitric-oxide synthase activity;GO:0071875//adrenergic receptor signaling pathway;GO:1903140//regulation of establishment of endothelial barrier;GO:1904997//regulation of leukocyte adhesion to arterial endothelial cell	--
ENSG00000175894	0	0.012	0	0	0	0	0	1	0	0	0	0	TSPEAR	thrombospondin type laminin G domain and EAR repeats [Source:HGNC Symbol;Acc:HGNC:1268]	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0003674//molecular_function	GO:0007165//signal transduction;GO:0007219//Notch signaling pathway;GO:0007605//sensory perception of sound;GO:0008593//regulation of Notch signaling pathway;GO:0022405//hair cycle process;GO:0034505//tooth mineralization	--
ENSG00000175895	3.759	3.581	3.533	4.51	3.639	4.108	202	205	157	201	185	159	PLEKHF2	pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757]	-	-	-	-	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0031901//early endosome membrane	GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0046872//metal ion binding	GO:0015031//protein transport	--
ENSG00000175899	3.441	3.683	4.092	1.68	1.597	2.415	329	354	289	119	129	168	A2M	alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03910	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0019899//enzyme binding;GO:0019959//interleukin-8 binding;GO:0019966//interleukin-1 binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding;GO:0043120//tumor necrosis factor binding;GO:0048306//calcium-dependent protein binding;GO:0048403//brain-derived neurotrophic factor binding;GO:0048406//nerve growth factor binding	"GO:0001553//luteinization;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0006953//acute-phase response;GO:0007584//response to nutrient;GO:0010037//response to carbon dioxide;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0034695//response to prostaglandin E;GO:0048863//stem cell differentiation;GO:0051384//response to glucocorticoid;GO:1990402//embryonic liver development"	--
ENSG00000175906	4.491	5.654	4.302	7.919	7.196	5.669	147	186	104	192	199	135	ARL4D	ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport	--
ENSG00000175920	7.812	8.429	8.27	7.743	8.004	8.836	413	447	323	304	358	340	DOK7	docking protein 7 [Source:HGNC Symbol;Acc:HGNC:26594]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding	GO:0007528//neuromuscular junction development;GO:0061098//positive regulation of protein tyrosine kinase activity	--
ENSG00000175928	51.487	46.822	46.253	35.382	37.647	50.551	6365	5818	4223	3240	3932	4547	LRRN1	leucine rich repeat neuronal 1 [Source:HGNC Symbol;Acc:HGNC:20980]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly	--
ENSG00000175931	10.107	11.377	11.62	11.838	10.236	10.659	916	1045	844	782	843	725	UBE2O	ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10581	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity;GO:0061631//ubiquitin conjugating enzyme activity	"GO:0006513//protein monoubiquitination;GO:0010951//negative regulation of endopeptidase activity;GO:0016567//protein ubiquitination;GO:0030513//positive regulation of BMP signaling pathway;GO:0042147//retrograde transport, endosome to Golgi;GO:0043066//negative regulation of apoptotic process;GO:0070534//protein K63-linked ubiquitination"	--
ENSG00000175938	21.236	20.837	21.564	22.858	22.605	23.403	836	863	673	670	770	684	ORAI3	ORAI calcium release-activated calcium modulator 3 [Source:HGNC Symbol;Acc:HGNC:28185]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K16058	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity	GO:0002115//store-operated calcium entry;GO:0070588//calcium ion transmembrane transport	--
ENSG00000175946	0.089	0.132	0.12	0.14	0.263	0.172	6	9	6	7	15	6	KLHL38	kelch like family member 38 [Source:HGNC Symbol;Acc:HGNC:34435]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000175970	16.287	16.072	17.969	13.579	14.797	19.889	1480	1468	1206	914	1136	1315	UNC119B	unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488]	-	-	-	-	GO:0005829//cytosol;GO:0005929//cilium;GO:0035869//ciliary transition zone;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0007399//nervous system development;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0042953//lipoprotein transport;GO:0060271//cilium assembly	--
ENSG00000175984	0.993	0.807	0.692	0.734	0.884	0.472	104	88	52	58	79	36	DENND2C	DENN domain containing 2C [Source:HGNC Symbol;Acc:HGNC:24748]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000175985	0.039	0.029	0	0.146	0.012	0	4	3	0	11	1	0	PLEKHD1	pleckstrin homology and coiled-coil domain containing D1 [Source:HGNC Symbol;Acc:HGNC:20148]	-	-	-	-	-	-	-	--
ENSG00000176009	0	0	0	0	0	0	0	0	0	0	0	0	ASCL3	achaete-scute family bHLH transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:740]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	bHLH
ENSG00000176014	108.716	107.075	123.784	132.327	125.85	127.479	3707.44	3679.21	3185.09	3488.77	3766.86	3249.14	TUBB6	tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process	--
ENSG00000176018	10.905	7.232	7.046	7.015	7.982	7.701	877	608	451	428	529	476	LYSMD3	LysM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26969]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007030//Golgi organization	--
ENSG00000176020	1.007	1.149	1.693	1.096	1.521	0.377	59.68	68.4	74.06	48.09	76.11	16.26	AMIGO3	adhesion molecule with Ig like domain 3 [Source:HGNC Symbol;Acc:HGNC:24075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007399//nervous system development;GO:0007420//brain development;GO:0010977//negative regulation of neuron projection development;GO:0051965//positive regulation of synapse assembly	--
ENSG00000176022	15.864	15.133	17.431	16.011	17.943	18.662	923	885	749	690	882	790	B3GALT6	"beta-1,3-galactosyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:17978]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K00734;K00734;K00734	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	"GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0035250//UDP-galactosyltransferase activity;GO:0047220//galactosylxylosylprotein 3-beta-galactosyltransferase activity"	GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000176024	1.753	1.976	2.291	1.744	2.564	2.694	107	111	80	54	67	56	ZNF613	zinc finger protein 613 [Source:HGNC Symbol;Acc:HGNC:25827]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000176029	0	0	0.035	0	0.061	0	0	0	1	0	2	0	C11orf16	chromosome 11 open reading frame 16 [Source:HGNC Symbol;Acc:HGNC:1169]	-	-	-	-	-	-	-	--
ENSG00000176040	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS7	transmembrane serine protease 7 [Source:HGNC Symbol;Acc:HGNC:30846]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000176046	67.991	83.213	72.537	37.101	43.929	81.513	1685.4	1863	1243	707.22	876.57	1399.42	NUPR1	"nuclear protein 1, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29990]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15626	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032993//protein-DNA complex;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0010698//acetyltransferase activator activity	"GO:0002526//acute inflammatory response;GO:0006473//protein acetylation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009636//response to toxic substance;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0031401//positive regulation of protein modification process;GO:0035914//skeletal muscle cell differentiation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0045786//negative regulation of cell cycle;GO:0045787//positive regulation of cell cycle;GO:0045820//negative regulation of glycolytic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048147//negative regulation of fibroblast proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0050790//regulation of catalytic activity;GO:0062099//negative regulation of programmed necrotic cell death;GO:0065003//protein-containing complex assembly;GO:0150078//positive regulation of neuroinflammatory response;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902902//negative regulation of autophagosome assembly;GO:1903862//positive regulation of oxidative phosphorylation;GO:1904036//negative regulation of epithelial cell apoptotic process;GO:1904691//negative regulation of type B pancreatic cell proliferation;GO:1905897//regulation of response to endoplasmic reticulum stress;GO:2000194//regulation of female gonad development;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000176049	0.563	0.5	0.359	0.146	0.24	0.116	46	36	21	9	20	6	JAKMIP2	janus kinase and microtubule interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:29067]	-	-	-	-	GO:0005794//Golgi apparatus	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019900//kinase binding	-	--
ENSG00000176055	3.199	2.355	2.794	2.915	2.715	2.404	277	210	180	186	202	151	MBLAC2	metallo-beta-lactamase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33711]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008800//beta-lactamase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008150//biological_process	--
ENSG00000176058	113.392	111.606	114.802	134.783	137.094	129.168	6242	6174	4661	5501	6373	5176	TPRN	taperin [Source:HGNC Symbol;Acc:HGNC:26894]	-	-	-	-	GO:0032420//stereocilium;GO:0042995//cell projection;GO:0120044//stereocilium base	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0019902//phosphatase binding	GO:0007605//sensory perception of sound;GO:0060088//auditory receptor cell stereocilium organization;GO:0120045//stereocilium maintenance	--
ENSG00000176076	0.327	0	0.133	0.044	0.116	0.135	10	0	3	1	3	3	KCNE5	potassium voltage-gated channel subfamily E regulatory subunit 5 [Source:HGNC Symbol;Acc:HGNC:6241]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0008016//regulation of heart contraction;GO:0060048//cardiac muscle contraction;GO:0060306//regulation of membrane repolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086011//membrane repolarization during action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086014//atrial cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:1903765//negative regulation of potassium ion export across plasma membrane;GO:2001257//regulation of cation channel activity	--
ENSG00000176083	0	0	0	0	0	0	0	0	0	0	0	0	ZNF683	zinc finger protein 683 [Source:HGNC Symbol;Acc:HGNC:28495]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0032689//negative regulation of interferon-gamma production;GO:0032823//regulation of natural killer cell differentiation;GO:0032826//regulation of natural killer cell differentiation involved in immune response;GO:0033082//regulation of extrathymic T cell differentiation;GO:0045087//innate immune response;GO:0050852//T cell receptor signaling pathway;GO:0051136//regulation of NK T cell differentiation;GO:1904637//cellular response to ionomycin	zf-C2H2
ENSG00000176087	34.986	35.51	37.222	48.338	41.36	40.645	1573.95	1613.75	1273	1612.84	1615.89	1358	SLC35A4	solute carrier family 35 member A4 [Source:HGNC Symbol;Acc:HGNC:20753]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	GO:0005515//protein binding;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0032056//positive regulation of translation in response to stress;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport	--
ENSG00000176092	0.023	0	0	0	0	0.075	3	0	0	0	0	1	CRYBG2	crystallin beta-gamma domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17295]	-	-	-	-	-	GO:0030246//carbohydrate binding	-	--
ENSG00000176095	22.775	23.529	24.715	24.776	27.389	27.625	2030	2090	1674	1689	1936	1725	IP6K1	inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360]	Environmental Information Processing	Signal transduction	ko04070//Phosphatidylinositol signaling system	K07756	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0000829//inositol heptakisphosphate kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0052836//inositol 5-diphosphate pentakisphosphate 5-kinase activity;GO:0052839//inositol diphosphate tetrakisphosphate kinase activity"	GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000176101	48.302	52.216	59.717	59.447	61.282	71.182	861	936	786	783	918	922	SSNA1	SS nuclear autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:11321]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0042073//intraciliary transport;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway	--
ENSG00000176102	8.181	7.894	8.389	7.268	9.543	7.57	358	382	276	247	330.99	233	CSTF3	cleavage stimulation factor subunit 3 [Source:HGNC Symbol;Acc:HGNC:2485]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14408	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006378//mRNA polyadenylation;GO:0006379//mRNA cleavage;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0031123//RNA 3'-end processing;GO:0031124//mRNA 3'-end processing	--
ENSG00000176105	13.489	9.951	10.476	7.166	7.624	9.8	1290	956	740	508	616	681	YES1	"YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841]"	Cellular Processes	Cellular community - eukaryotes	ko04520//Adherens junction	K05705	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0044325//transmembrane transporter binding	GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010827//regulation of glucose transmembrane transport;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0031295//T cell costimulation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043114//regulation of vascular permeability;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048013//ephrin receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050900//leukocyte migration;GO:0071300//cellular response to retinoic acid;GO:0071560//cellular response to transforming growth factor beta stimulus	--
ENSG00000176108	13.762	13.028	15.597	15.333	13.992	15.393	475	449	390	392	408	380	CHMP6	charged multivesicular body protein 6 [Source:HGNC Symbol;Acc:HGNC:25675]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12195;K12195	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005643//nuclear pore;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding	GO:0001778//plasma membrane repair;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0015031//protein transport;GO:0016032//viral process;GO:0016236//macroautophagy;GO:0031468//nuclear membrane reassembly;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0042176//regulation of protein catabolic process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046761//viral budding from plasma membrane;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:0140014//mitotic nuclear division;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904902//ESCRT III complex assembly	--
ENSG00000176125	1.211	1.012	0.394	1.243	0.975	1.199	25	21	6	19	17	18	UFSP1	UFM1 specific peptidase 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:33821]	-	-	-	-	-	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000176136	0.168	0.251	0	0.049	0	0.1	6	9	0	1	0	2	MC5R	melanocortin 5 receptor [Source:HGNC Symbol;Acc:HGNC:6933]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04203	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004977//melanocortin receptor activity;GO:0005515//protein binding;GO:0042562//hormone binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process"	--
ENSG00000176142	7.64	6.558	8.075	6.877	10.021	7.933	392	454	355	295	388	340	TMEM39A	transmembrane protein 39A [Source:HGNC Symbol;Acc:HGNC:25600]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006914//autophagy;GO:0045070//positive regulation of viral genome replication;GO:1901097//negative regulation of autophagosome maturation;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000176148	3.826	3.859	4.922	4.155	4.869	3.729	207	209	190	152	208.01	135	TCP11L1	t-complex 11 like 1 [Source:HGNC Symbol;Acc:HGNC:25655]	-	-	-	-	GO:0005874//microtubule	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000176153	0	0	0	0	0	0	0	0	0	0	0	0	GPX2	glutathione peroxidase 2 [Source:HGNC Symbol;Acc:HGNC:4554]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity	GO:0006979//response to oxidative stress;GO:0022900//electron transport chain;GO:0098869//cellular oxidant detoxification	--
ENSG00000176155	5.319	4.775	3.239	6.386	4.364	3.228	247	235	161	232	243	160	CCDC57	coiled-coil domain containing 57 [Source:HGNC Symbol;Acc:HGNC:27564]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0007099//centriole replication;GO:0045931//positive regulation of mitotic cell cycle;GO:0060271//cilium assembly	--
ENSG00000176160	0	0	0	0	0	0	0	0	0	0	0	0	HSF5	heat shock transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:26862]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000176165	0	0.027	0	0	0	0	0	2	0	0	0	0	FOXG1	forkhead box G1 [Source:HGNC Symbol;Acc:HGNC:3811]	Environmental Information Processing	Signal transduction	ko04068//FoxO signaling pathway	K09385	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007346//regulation of mitotic cell cycle;GO:0007420//brain development;GO:0007568//aging;GO:0009953//dorsal/ventral pattern formation;GO:0010468//regulation of gene expression;GO:0016199//axon midline choice point recognition;GO:0021852//pyramidal neuron migration to cerebral cortex;GO:0021954//central nervous system neuron development;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0030900//forebrain development;GO:0042472//inner ear morphogenesis;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048664//neuron fate determination;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0051726//regulation of cell cycle;GO:2000177//regulation of neural precursor cell proliferation"	Fork_head
ENSG00000176170	1.747	1.819	2.235	1.631	1.874	1.669	69	70	67	46	62	36	SPHK1	sphingosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11240]	Metabolism;Environmental Information Processing;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Signal transduction;Immune system;Signal transduction;Signal transduction;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04371//Apelin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04370//VEGF signaling pathway;ko00600//Sphingolipid metabolism	K04718;K04718;K04718;K04718;K04718;K04718;K04718;K04718;K04718	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0001727//lipid kinase activity;GO:0003677//DNA binding;GO:0003951//NAD+ kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0008481//sphinganine kinase activity;GO:0016301//kinase activity;GO:0016407//acetyltransferase activity;GO:0016740//transferase activity;GO:0017050//D-erythro-sphingosine kinase activity;GO:0038036//sphingosine-1-phosphate receptor activity;GO:0051721//protein phosphatase 2A binding	GO:0001568//blood vessel development;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006473//protein acetylation;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0006954//inflammatory response;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0030100//regulation of endocytosis;GO:0030148//sphingolipid biosynthetic process;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0031398//positive regulation of protein ubiquitination;GO:0032651//regulation of interleukin-1 beta production;GO:0032740//positive regulation of interleukin-17 production;GO:0034612//response to tumor necrosis factor;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0045931//positive regulation of mitotic cell cycle;GO:0045987//positive regulation of smooth muscle contraction;GO:0046512//sphingosine biosynthetic process;GO:0046521//sphingoid catabolic process;GO:0046834//lipid phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0050764//regulation of phagocytosis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070301//cellular response to hydrogen peroxide;GO:0071363//cellular response to growth factor stimulus;GO:0071897//DNA biosynthetic process;GO:0090520//sphingolipid mediated signaling pathway;GO:0150077//regulation of neuroinflammatory response;GO:1900060//negative regulation of ceramide biosynthetic process;GO:1900745//positive regulation of p38MAPK cascade;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1903978//regulation of microglial cell activation;GO:1905364//regulation of endosomal vesicle fusion	--
ENSG00000176171	36.993	35.493	33.85	36.461	31.835	38.07	1144	1096	756	821	823	820	BNIP3	BCL2 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:1084]	Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases	Infectious disease: bacterial;Transport and catabolism;Signal transduction;Transport and catabolism;Infectious disease: bacterial	ko05131//Shigellosis;ko04140//Autophagy - animal;ko04068//FoxO signaling pathway;ko04137//Mitophagy - animal;ko05134//Legionellosis	K15464;K15464;K15464;K15464;K15464	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031307//integral component of mitochondrial outer membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051020//GTPase binding	GO:0000422//autophagy of mitochondrion;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0008219//cell death;GO:0009617//response to bacterium;GO:0010508//positive regulation of autophagy;GO:0010637//negative regulation of mitochondrial fusion;GO:0010659//cardiac muscle cell apoptotic process;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010821//regulation of mitochondrion organization;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0010940//positive regulation of necrotic cell death;GO:0016239//positive regulation of macroautophagy;GO:0021987//cerebral cortex development;GO:0035694//mitochondrial protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043067//regulation of programmed cell death;GO:0043068//positive regulation of programmed cell death;GO:0043243//positive regulation of protein-containing complex disassembly;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0045837//negative regulation of membrane potential;GO:0046902//regulation of mitochondrial membrane permeability;GO:0048102//autophagic cell death;GO:0048678//response to axon injury;GO:0048709//oligodendrocyte differentiation;GO:0050873//brown fat cell differentiation;GO:0051402//neuron apoptotic process;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0051607//defense response to virus;GO:0055093//response to hyperoxia;GO:0060548//negative regulation of cell death;GO:0070301//cellular response to hydrogen peroxide;GO:0071260//cellular response to mechanical stimulus;GO:0071279//cellular response to cobalt ion;GO:0071456//cellular response to hypoxia;GO:0072593//reactive oxygen species metabolic process;GO:0090141//positive regulation of mitochondrial fission;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090649//response to oxygen-glucose deprivation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0097345//mitochondrial outer membrane permeabilization;GO:0140507//granzyme-mediated programmed cell death signaling pathway;GO:1901998//toxin transport;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1903599//positive regulation of autophagy of mitochondrion;GO:1903715//regulation of aerobic respiration;GO:1990144//intrinsic apoptotic signaling pathway in response to hypoxia;GO:2000378//negative regulation of reactive oxygen species metabolic process	--
ENSG00000176177	0	0	0	0	0	0	0	0	0	0	0	0	ENTHD1	ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0030125//clathrin vesicle coat	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0030276//clathrin binding	GO:0006897//endocytosis	--
ENSG00000176182	2.085	1.847	2.066	3.09	2.919	2.376	82	73	60	90	97	68	MYPOP	"Myb related transcription factor, partner of profilin [Source:HGNC Symbol;Acc:HGNC:20178]"	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000176194	0.143	0	0.13	0.194	0.17	0	3	0	2	3	3	0	CIDEA	cell death inducing DFFA like effector a [Source:HGNC Symbol;Acc:HGNC:1976]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0042803//protein homodimerization activity	GO:0001659//temperature homeostasis;GO:0001818//negative regulation of cytokine production;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0008219//cell death;GO:0010890//positive regulation of sequestering of triglyceride;GO:0019915//lipid storage;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035634//response to stilbenoid;GO:0042981//regulation of apoptotic process;GO:0050995//negative regulation of lipid catabolic process;GO:0070417//cellular response to cold;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900118//negative regulation of execution phase of apoptosis;GO:1902510//regulation of apoptotic DNA fragmentation	--
ENSG00000176198	0	0	0	0	0	0	0	0	0	0	0	0	OR11H4	olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176200	0	0	0	0	0	0	0	0	0	0	0	0	OR4D11	olfactory receptor family 4 subfamily D member 11 [Source:HGNC Symbol;Acc:HGNC:15174]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176204	2.412	2.573	2.848	2.779	2.202	4.407	152	146.85	137	136	130	179	LRRTM4	leucine rich repeat transmembrane neuronal 4 [Source:HGNC Symbol;Acc:HGNC:19411]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	-	--
ENSG00000176208	0.317	0.126	0.123	0.133	0.125	0.118	37	18	13	14	15	11	ATAD5	ATPase family AAA domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25752]	-	-	-	-	GO:0005634//nucleus;GO:0031391//Elg1 RFC-like complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0061860//DNA clamp unloader activity	GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030890//positive regulation of B cell proliferation;GO:0033260//nuclear DNA replication;GO:0042770//signal transduction in response to DNA damage;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045190//isotype switching;GO:0045740//positive regulation of DNA replication;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090618//DNA clamp unloading;GO:1901990//regulation of mitotic cell cycle phase transition;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902751//positive regulation of cell cycle G2/M phase transition	--
ENSG00000176209	23.026	21.702	22.547	20.375	18.429	26.547	444	419	325	292	304	326	SMIM19	small integral membrane protein 19 [Source:HGNC Symbol;Acc:HGNC:25166]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000176219	0	0	0	0	0	0	0	0	0	0	0	0	OR11H6	olfactory receptor family 11 subfamily H member 6 [Source:HGNC Symbol;Acc:HGNC:15349]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176222	0.549	1.012	0.637	1.271	0.741	0.43	21	39	18	36	24	12	ZNF404	zinc finger protein 404 [Source:HGNC Symbol;Acc:HGNC:19417]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000176225	2.416	1.501	2.329	0.697	0.808	1.054	261	191	153	68	95	74	RTTN	rotatin [Source:HGNC Symbol;Acc:HGNC:18654]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0007099//centriole replication;GO:0007368//determination of left/right symmetry;GO:0010457//centriole-centriole cohesion;GO:0032053//ciliary basal body organization;GO:0044782//cilium organization	--
ENSG00000176230	0	0	0	0	0	0	0	0	0	0	0	0	OR4K17	olfactory receptor family 4 subfamily K member 17 [Source:HGNC Symbol;Acc:HGNC:15355]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176231	0	0	0	0	0	0	0	0	0	0	0	0	OR10H4	olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000176239	0	0	0	0	0	0	0	0	0	0	0	0	OR51B6	olfactory receptor family 51 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:19600]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176244	0.386	0.256	0.213	0.135	0.186	0.138	27	18	11	7	11	7	ACBD7	acyl-CoA binding domain containing 7 [Source:HGNC Symbol;Acc:HGNC:17715]	-	-	-	-	-	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006631//fatty acid metabolic process	--
ENSG00000176246	0	0	0	0	0	0	0	0	0	0	0	0	OR4L1	olfactory receptor family 4 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:15356]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176248	11.912	12.917	14.334	14.929	13.132	14.65	656	715	583	609	611	587	ANAPC2	anaphase promoting complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19989]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03349;K03349;K03349;K03349;K03349	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0007399//nervous system development;GO:0010629//negative regulation of gene expression;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031915//positive regulation of synaptic plasticity;GO:0045773//positive regulation of axon extension;GO:0050775//positive regulation of dendrite morphogenesis;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0090129//positive regulation of synapse maturation	--
ENSG00000176253	0	0	0	0	0	0	0	0	0	0	0	0	OR4K13	olfactory receptor family 4 subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:15351]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176256	0	0	0	0	0	0	0	0	0	0	0	0	HMGB4	high mobility group box 4 [Source:HGNC Symbol;Acc:HGNC:24954]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome	"GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008301//DNA binding, bending"	GO:0006357//regulation of transcription by RNA polymerase II	HMG
ENSG00000176261	4.1	5.073	4.353	5.679	3.126	4.862	79	75	50	63	56	51	ZBTB8OS	zinc finger and BTB domain containing 8 opposite strand [Source:HGNC Symbol;Acc:HGNC:24094]	-	-	-	-	GO:0005654//nucleoplasm;GO:0072669//tRNA-splicing ligase complex	GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0008033//tRNA processing"	--
ENSG00000176269	0	0	0	0	0	0	0	0	0	0	0	0	OR4F21	olfactory receptor family 4 subfamily F member 21 [Source:HGNC Symbol;Acc:HGNC:19583]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176273	5.812	5.084	6.557	6.257	6.226	9.227	379	324	276	262	323	360	SLC35G1	solute carrier family 35 member G1 [Source:HGNC Symbol;Acc:HGNC:26607]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0051480//regulation of cytosolic calcium ion concentration;GO:1990034//calcium ion export across plasma membrane	--
ENSG00000176281	0	0	0	0	0	0	0	0	0	0	0	0	OR4K5	olfactory receptor family 4 subfamily K member 5 [Source:HGNC Symbol;Acc:HGNC:14745]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176290	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000176293	2.16	2.314	1.774	1.834	2.117	2.094	144.95	151.05	80.9	91.54	108.67	90.76	ZNF135	zinc finger protein 135 [Source:HGNC Symbol;Acc:HGNC:12919]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis"	zf-C2H2
ENSG00000176294	0	0	0	0	0	0	0	0	0	0	0	0	OR4N2	olfactory receptor family 4 subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:14742]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176299	0	0	0	0	0	0	0	0	0	0	0	0	OR4M1	olfactory receptor family 4 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:14735]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176302	0	0	0	0	0	0	0	0	0	0	0	0	FOXR1	forkhead box R1 [Source:HGNC Symbol;Acc:HGNC:29980]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Fork_head
ENSG00000176340	209.436	200.986	245.648	324.245	239.926	281.138	2146	2070	1859	2461	2077	2096	COX8A	cytochrome c oxidase subunit 8A [Source:HGNC Symbol;Acc:HGNC:2294]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding	"GO:0006091//generation of precursor metabolites and energy;GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000176358	0	0	0	0	0	0	0	0	0	0	0	0	TAC4	tachykinin precursor 4 [Source:HGNC Symbol;Acc:HGNC:16641]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05241	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0031835//substance P receptor binding;GO:0031837//substance K receptor binding;GO:0048018//receptor ligand activity	GO:0003085//negative regulation of systemic arterial blood pressure;GO:0006954//inflammatory response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007217//tachykinin receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0051930//regulation of sensory perception of pain;GO:1902093//positive regulation of flagellated sperm motility;GO:1904057//negative regulation of sensory perception of pain	--
ENSG00000176371	5.337	6.455	4.665	5.611	5.774	5.239	358	400	262	253	286	270	ZSCAN2	zinc finger and SCAN domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20994]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	zf-C2H2
ENSG00000176381	1.445	1.286	1.921	1.747	2.394	3.404	84	74	91	83	109	125	PRR18	proline rich 18 [Source:HGNC Symbol;Acc:HGNC:28574]	-	-	-	-	-	-	-	--
ENSG00000176383	0.064	0.192	0	0.059	0.078	0	3.66	11.02	0	2.49	3.77	0	B3GNT4	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:15683]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07971;K07971	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0008194//UDP-glycosyltransferase activity;GO:0008457//beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity"	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0030311//poly-N-acetyllactosamine biosynthetic process	--
ENSG00000176386	17.547	15.86	13.49	15.02	13.627	15.976	317	288	180	201	208	210	CDC26	cell division cycle 26 [Source:HGNC Symbol;Acc:HGNC:17839]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03359;K03359;K03359;K03359;K03359	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000176387	0.051	0.025	0	0	0	0	2	1	0	0	0	0	HSD11B2	hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Excretory system	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko04960//Aldosterone-regulated sodium reabsorption	K00071;K00071;K00071	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005496//steroid binding;GO:0016491//oxidoreductase activity;GO:0051287//NAD binding;GO:0070523//11-beta-hydroxysteroid dehydrogenase (NAD+) activity	GO:0001666//response to hypoxia;GO:0002017//regulation of blood volume by renal aldosterone;GO:0006629//lipid metabolic process;GO:0007565//female pregnancy;GO:0008211//glucocorticoid metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0032094//response to food;GO:0032868//response to insulin;GO:0034650//cortisol metabolic process;GO:0048545//response to steroid hormone;GO:0051384//response to glucocorticoid	--
ENSG00000176390	1.326	1.414	1.219	0.725	1.114	1.807	79	63	46	32	43	75	CRLF3	cytokine receptor like factor 3 [Source:HGNC Symbol;Acc:HGNC:17177]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0030308//negative regulation of cell growth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000176393	14.423	14.557	17.324	17.175	16.346	16.581	696	709	573	602	677	570	RNPEP	arginyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:10078]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0004301//epoxide hydrolase activity;GO:0008233//peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis	--
ENSG00000176396	10.371	11.043	11.081	10.602	10.001	12.478	313	335	247	237	255	274	EID2	EP300 interacting inhibitor of differentiation 2 [Source:HGNC Symbol;Acc:HGNC:28292]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046332//SMAD binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0007183//SMAD protein complex assembly;GO:0007517//muscle organ development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000176399	3.728	3.546	3.564	2.412	2.656	3.369	432	413	305	207	260	284	DMRTA1	DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001541//ovarian follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007548//sex differentiation;GO:0060179//male mating behavior"	DM
ENSG00000176401	0.723	0.566	0.805	0.419	1.07	0.746	28	22	23	12	35	21	EID2B	EP300 interacting inhibitor of differentiation 2B [Source:HGNC Symbol;Acc:HGNC:26796]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000176402	0	0	0	0	0	0	0	0	0	0	0	0	GJC3	gap junction protein gamma 3 [Source:HGNC Symbol;Acc:HGNC:17495]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043209//myelin sheath	GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007605//sensory perception of sound;GO:0042552//myelination;GO:0055085//transmembrane transport	--
ENSG00000176406	0.409	0.322	0.281	0.345	0.268	0.195	41	37	27	25	22	14	RIMS2	regulating synaptic membrane exocytosis 2 [Source:HGNC Symbol;Acc:HGNC:17283]	Organismal Systems	Endocrine system	ko04911//Insulin secretion	K15297	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0030154//cell differentiation;GO:0042391//regulation of membrane potential;GO:0048167//regulation of synaptic plasticity;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0050806//positive regulation of synaptic transmission;GO:0061669//spontaneous neurotransmitter secretion;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:1903861//positive regulation of dendrite extension;GO:2000463//positive regulation of excitatory postsynaptic potential	--
ENSG00000176407	20.199	19.745	20.266	19.033	17.446	28.762	1029	980	708	661	781	760	KCMF1	potassium channel modulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:20589]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043226//organelle;GO:0045202//synapse;GO:1904813//ficolin-1-rich granule lumen	GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0099536//synaptic signaling	--
ENSG00000176410	4.696	5.409	5.174	5.903	5.648	6.245	247	286	201	230	251	239	DNAJC30	DnaJ heat shock protein family (Hsp40) member C30 [Source:HGNC Symbol;Acc:HGNC:16410]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006754//ATP biosynthetic process;GO:0007420//brain development;GO:1905706//regulation of mitochondrial ATP synthesis coupled proton transport	--
ENSG00000176422	0.906	0.778	1.105	1.151	0.88	1.063	202.39	174.78	182.28	190.36	166.01	172.73	SPRYD4	SPRY domain containing 4 [Source:HGNC Symbol;Acc:HGNC:27468]	-	-	-	-	GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000176428	2.384	2.727	2.058	3.218	3.245	2.99	80	92	51	80	92	73	VPS37D	VPS37D subunit of ESCRT-I [Source:HGNC Symbol;Acc:HGNC:18287]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12185	GO:0000813//ESCRT I complex;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006612//protein targeting to membrane;GO:0006623//protein targeting to vacuole;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046907//intracellular transport	--
ENSG00000176435	0	0.023	0.062	0	0.027	0	0	1	2	0	1	0	CLEC14A	C-type lectin domain containing 14A [Source:HGNC Symbol;Acc:HGNC:19832]	-	-	-	-	GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0050840//extracellular matrix binding;GO:1990430//extracellular matrix protein binding	GO:0001946//lymphangiogenesis;GO:0002040//sprouting angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0016477//cell migration;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0036325//vascular endothelial growth factor receptor-3 signaling pathway	--
ENSG00000176438	0.142	0.169	0.302	0.208	0.173	0.295	37	38	40	19	39	20	SYNE3	spectrin repeat containing nuclear envelope family member 3 [Source:HGNC Symbol;Acc:HGNC:19861]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0051015//actin filament binding;GO:0140444//cytoskeleton-nuclear membrane anchor activity	GO:0007010//cytoskeleton organization;GO:0007097//nuclear migration;GO:0008360//regulation of cell shape;GO:0090150//establishment of protein localization to membrane	--
ENSG00000176444	11.244	11.434	11.369	10.657	11.926	10.877	488	498	369	339	437	338	CLK2	CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0010212//response to ionizing radiation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043484//regulation of RNA splicing;GO:0045721//negative regulation of gluconeogenesis;GO:0046777//protein autophosphorylation	--
ENSG00000176454	3.429	4.165	4.432	3.577	4.484	4.927	154	188	147	119	153	161	LPCAT4	lysophosphatidylcholine acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:30059]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00565//Ether lipid metabolism	K13512;K13512;K13512	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047166//1-alkenylglycerophosphoethanolamine O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0071617//lysophospholipid acyltransferase activity;GO:0106262//1-acylglycerophosphoethanolamine O-acyltransferase activity;GO:0106263//1-acylglycerophosphoserine O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling	--
ENSG00000176463	8.499	9.334	11.567	9.596	10.703	10.515	691	786	686	579	710	630	SLCO3A1	solute carrier organic anion transporter family member 3A1 [Source:HGNC Symbol;Acc:HGNC:10952]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006811//ion transport;GO:0015732//prostaglandin transport;GO:0043252//sodium-independent organic anion transport;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000176472	0.402	0.949	0.588	0.898	0.7	0.203	13	26	15	22	16	5	ZNF575	zinc finger protein 575 [Source:HGNC Symbol;Acc:HGNC:27606]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000176473	7.719	7.574	7.849	7.773	7.556	9.722	293	287	225	218	255	277	WDR25	WD repeat domain 25 [Source:HGNC Symbol;Acc:HGNC:21064]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000176476	10.399	11.505	11.095	9.266	11.669	12.883	250	278	197	165	237	223	SGF29	SAGA complex associated factor 29 [Source:HGNC Symbol;Acc:HGNC:25156]	-	-	-	-	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0070461//SAGA-type complex;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0031063//regulation of histone deacetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0071169//establishment of protein localization to chromatin;GO:0090043//regulation of tubulin deacetylation"	--
ENSG00000176485	92.904	92.512	85.336	90.998	85.611	84.761	2743	2676	1871	1876	2038	1864	PLAAT3	phospholipase A and acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17825]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko04923//Regulation of lipolysis in adipocytes;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16817;K16817;K16817;K16817;K16817;K16817;K16817;K16817	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008970//phospholipase A1 activity;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006644//phospholipid metabolic process;GO:0007031//peroxisome organization;GO:0008654//phospholipid biosynthetic process;GO:0009617//response to bacterium;GO:0016042//lipid catabolic process;GO:0030397//membrane disassembly;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0046485//ether lipid metabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process;GO:0070306//lens fiber cell differentiation;GO:1903008//organelle disassembly;GO:1904177//regulation of adipose tissue development	--
ENSG00000176490	13.273	13.319	15.227	15.453	14.021	15.849	930	938	788	802	830	808	DIRAS1	DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:19127]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0007165//signal transduction	--
ENSG00000176495	0	0	0	0	0	0	0	0	0	0	0	0	OR5AN1	olfactory receptor family 5 subfamily AN member 1 [Source:HGNC Symbol;Acc:HGNC:15255]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176510	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000176531	4.657	6.194	3.8	4.156	5.229	3.901	135	144	92	84	108	85	PHLDB3	pleckstrin homology like domain family B member 3 [Source:HGNC Symbol;Acc:HGNC:30499]	-	-	-	-	-	GO:0005515//protein binding;GO:0019899//enzyme binding	-	--
ENSG00000176532	0.146	0.145	0.158	0.197	0.518	0.401	5	5	4	5	15	10	PRR15	proline rich 15 [Source:HGNC Symbol;Acc:HGNC:22310]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000176533	10.578	10.043	11.629	13.705	12.344	14.918	920	845	747	875	907	944	GNG7	G protein subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:4410]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Sensory system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04740//Olfactory transduction;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543;K04543	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway	--
ENSG00000176540	0	0	0	0	0	0	0	0	0	0	0	0	OR4C5	olfactory receptor family 4 subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:14702]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176542	1.495	1.159	1.43	1.387	1.172	1.128	425	331	269	175	239	196	USF3	upstream transcription factor family member 3 [Source:HGNC Symbol;Acc:HGNC:30494]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046983//protein dimerization activity"	GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0045944//positive regulation of transcription by RNA polymerase II	bHLH
ENSG00000176547	0	0	0	0	0	0	0	0	0	0	0	0	OR4C3	olfactory receptor family 4 subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:14697]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176555	0	0	0	0	0	0	0	0	0	0	0	0	OR4S1	olfactory receptor family 4 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:14705]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176563	0.151	0.1	0.218	0.135	0.078	0.392	10.21	6.81	8.93	6.77	4.44	7.8	CNTD1	cyclin N-terminal domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26847]	-	-	-	-	GO:0005694//chromosome;GO:0035861//site of double-strand break	-	GO:0007131//reciprocal meiotic recombination;GO:0007283//spermatogenesis;GO:0051445//regulation of meiotic cell cycle	--
ENSG00000176566	0	0	0	0	0	0	0	0	0	0	0	0	DCAF4L2	DDB1 and CUL4 associated factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:26657]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000176567	0	0	0	0	0	0	0	0	0	0	0	0	OR4X1	olfactory receptor family 4 subfamily X member 1 [Source:HGNC Symbol;Acc:HGNC:14854]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176571	0.055	0	0.075	0.099	0	0	1	0	1	1	0	0	CNBD1	cyclic nucleotide binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26663]	-	-	-	-	-	-	-	--
ENSG00000176595	8.232	8.03	8.17	8.646	9.223	8.763	1180	1157	865	918	1117	914	KBTBD11	kelch repeat and BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29104]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000176597	1.496	1.109	1.124	1.028	1.337	1.399	120	95	65	58.61	82	81	B3GNT5	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K03766;K03766	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0005515//protein binding;GO:0008457//beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047256//lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0009247//glycolipid biosynthetic process;GO:0016266//O-glycan processing	--
ENSG00000176601	0.153	0.177	0.097	0.097	0.168	0	16	9	5	3	3	0	MAP3K19	mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000176619	13.993	13.684	16.918	15.941	16.895	15.371	1345	1322	1201	1135	1372	1075	LMNB2	lamin B2 [Source:HGNC Symbol;Acc:HGNC:6638]	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K07611	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0031965//nuclear membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008150//biological_process	--
ENSG00000176623	13.725	11.056	9.789	11.688	8.61	9.749	520	451	292	322	316	254	RMDN1	regulator of microtubule dynamics 1 [Source:HGNC Symbol;Acc:HGNC:24285]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0097431//mitotic spindle pole	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0007052//mitotic spindle organization;GO:0051315//attachment of mitotic spindle microtubules to kinetochore	--
ENSG00000176624	16.674	16.052	17.2	16.807	15.008	18.877	1332	1288	1010	916	919	1028	MEX3C	mex-3 RNA binding family member C [Source:HGNC Symbol;Acc:HGNC:28040]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0003415//chondrocyte hypertrophy;GO:0016567//protein ubiquitination;GO:0045598//regulation of fat cell differentiation;GO:0097009//energy homeostasis	--
ENSG00000176635	1.987	1.374	1.244	0.892	1.931	1.013	79	56	37	26	65	29	HORMAD2	HORMA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28383]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005813//centrosome;GO:0005829//cytosol	GO:0005515//protein binding	GO:0051177//meiotic sister chromatid cohesion;GO:0051321//meiotic cell cycle	--
ENSG00000176641	5.633	4.623	7.205	4.797	4.033	6.601	921	712	670	522	618	738	RNF152	ring finger protein 152 [Source:HGNC Symbol;Acc:HGNC:26811]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K15705	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031301//integral component of organelle membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0034198//cellular response to amino acid starvation;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000176658	25.687	22.206	24.67	26.565	25.501	29.405	2776	2458	1988	2106	2389	2354	MYO1D	myosin ID [Source:HGNC Symbol;Acc:HGNC:7598]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005790//smooth endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0016459//myosin complex;GO:0030424//axon;GO:0030425//dendrite;GO:0030673//axolemma;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043209//myelin sheath;GO:0070062//extracellular exosome;GO:0097440//apical dendrite	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0030050//vesicle transport along actin filament;GO:0051641//cellular localization;GO:0061502//early endosome to recycling endosome transport	--
ENSG00000176678	0.029	0.117	0.026	0.092	0.035	0	3	12	2	7	3	0	FOXL1	forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008301//DNA binding, bending;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007495//visceral mesoderm-endoderm interaction involved in midgut development;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0030111//regulation of Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030166//proteoglycan biosynthetic process;GO:0061146//Peyer's patch morphogenesis"	Fork_head
ENSG00000176679	0	0	0.074	0	0	0	0	0	1	0	0	0	TGIF2LY	TGFB induced factor homeobox 2 like Y-linked [Source:HGNC Symbol;Acc:HGNC:18569]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000176681	0.989	0.839	0.341	0.768	1.006	0.752	83.5	75.43	20.94	48.72	71.61	45.39	LRRC37A	leucine rich repeat containing 37A [Source:HGNC Symbol;Acc:HGNC:29069]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000176692	0.914	0.744	0.675	0.045	0.079	0.023	55	45	30	2	4	1	FOXC2	forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001568//blood vessel development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001756//somitogenesis;GO:0001822//kidney development;GO:0001945//lymph vessel development;GO:0001946//lymphangiogenesis;GO:0001974//blood vessel remodeling;GO:0003007//heart morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0008283//cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0009725//response to hormone;GO:0010595//positive regulation of endothelial cell migration;GO:0014032//neural crest cell development;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0035050//embryonic heart tube development;GO:0035470//positive regulation of vascular wound healing;GO:0043010//camera-type eye development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046620//regulation of organ growth;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048341//paraxial mesoderm formation;GO:0048343//paraxial mesodermal cell fate commitment;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048844//artery morphogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0072011//glomerular endothelium development;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072144//glomerular mesangial cell development;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0097746//blood vessel diameter maintenance;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1902257//negative regulation of apoptotic process involved in outflow tract morphogenesis"	Fork_head
ENSG00000176695	0	0	0	0	0	0	0	0	0	0	0	0	OR4F17	olfactory receptor family 4 subfamily F member 17 [Source:HGNC Symbol;Acc:HGNC:15381]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176697	1.25	0.9	0.573	0.391	0.418	0.524	103	76	35	24	29	32	BDNF	brain derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:1033]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Substance dependence;Nervous system;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04722//Neurotrophin signaling pathway;ko05030//Cocaine addiction	K04355;K04355;K04355;K04355;K04355;K04355;K04355;K04355;K04355	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0008021//synaptic vesicle;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005163//nerve growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007422//peripheral nervous system development;GO:0007613//memory;GO:0010832//negative regulation of myotube differentiation;GO:0010976//positive regulation of neuron projection development;GO:0021675//nerve development;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0031550//positive regulation of brain-derived neurotrophic factor receptor signaling pathway;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038180//nerve growth factor signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0048668//collateral sprouting;GO:0048672//positive regulation of collateral sprouting;GO:0048812//neuron projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0051965//positive regulation of synapse assembly;GO:1900122//positive regulation of receptor binding;GO:2000008//regulation of protein localization to cell surface;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000176714	3.691	3.928	3.227	2.923	2.909	3.097	157	163	103	99	113	102	CCDC121	coiled-coil domain containing 121 [Source:HGNC Symbol;Acc:HGNC:25833]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000176715	10.015	9.57	10.001	9.614	10.417	10.911	383	453	328	320	389	362	ACSF3	acyl-CoA synthetase family member 3 [Source:HGNC Symbol;Acc:HGNC:27288]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00061//Fatty acid biosynthesis"	K18660;K18660;K18660;K18660	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016405//CoA-ligase activity;GO:0016874//ligase activity;GO:0016878//acid-thiol ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0090409//malonyl-CoA synthetase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0090410//malonate catabolic process	--
ENSG00000176720	8.17	9.681	9.695	8.427	7.975	7.595	445	530	390	340	367	301	BOK	BCL2 family apoptosis regulator BOK [Source:HGNC Symbol;Acc:HGNC:1087]	Cellular Processes	Cell growth and death	ko04215//Apoptosis - multiple species	K02561	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031966//mitochondrial membrane;GO:0032588//trans-Golgi network membrane;GO:0033106//cis-Golgi network membrane;GO:0055038//recycling endosome membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0051400//BH domain binding	GO:0001836//release of cytochrome c from mitochondria;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007420//brain development;GO:0008584//male gonad development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0010506//regulation of autophagy;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0048709//oligodendrocyte differentiation;GO:0051259//protein complex oligomerization;GO:0051402//neuron apoptotic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051902//negative regulation of mitochondrial depolarization;GO:0060546//negative regulation of necroptotic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1900119//positive regulation of execution phase of apoptosis;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1901382//regulation of chorionic trophoblast cell proliferation;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:1904708//regulation of granulosa cell apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000176723	1.297	1.086	1.516	0.991	2.129	1.165	74	63	62	46	90	47	ZNF843	zinc finger protein 843 [Source:HGNC Symbol;Acc:HGNC:28710]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000176731	11.411	8.903	10.143	9.406	7.323	10.322	158.95	131.82	98.69	90.63	84.93	108.31	RBIS	ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0042254//ribosome biogenesis	--
ENSG00000176732	0.311	0.275	0.187	0.187	0.164	0.296	9	8	4	4	4	3	PFN4	profilin family member 4 [Source:HGNC Symbol;Acc:HGNC:31103]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway	K05759;K05759;K05759;K05759;K05759	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005938//cell cortex	GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0008289//lipid binding	GO:0042989//sequestering of actin monomers	--
ENSG00000176742	0	0	0	0	0	0	0	0	0	0	0	0	OR51V1	olfactory receptor family 51 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:19597]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176746	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB6	MAGE family member B6 [Source:HGNC Symbol;Acc:HGNC:23796]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000176749	1.15	1.106	1.5	0.824	0.983	0.89	79	91	78	50	68	53	CDK5R1	cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05030//Cocaine addiction	K11716;K11716;K11716	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016533//protein kinase 5 complex;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber;GO:0048471//perinuclear region of cytoplasm;GO:0098793//presynapse	GO:0002020//protease binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0035255//ionotropic glutamate receptor binding;GO:0043014//alpha-tubulin binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0045296//cadherin binding;GO:0046875//ephrin receptor binding;GO:0048487//beta-tubulin binding;GO:0051015//actin filament binding;GO:0061575//cyclin-dependent protein serine/threonine kinase activator activity	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0007158//neuron cell-cell adhesion;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007420//brain development;GO:0009792//embryo development ending in birth or egg hatching;GO:0016241//regulation of macroautophagy;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0021549//cerebellum development;GO:0021722//superior olivary nucleus maturation;GO:0021766//hippocampus development;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021819//layer formation in cerebral cortex;GO:0030182//neuron differentiation;GO:0030517//negative regulation of axon extension;GO:0031116//positive regulation of microtubule polymerization;GO:0031175//neuron projection development;GO:0032147//activation of protein kinase activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0042501//serine phosphorylation of STAT protein;GO:0043525//positive regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048013//ephrin receptor signaling pathway;GO:0048511//rhythmic process;GO:0061001//regulation of dendritic spine morphogenesis;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0090314//positive regulation of protein targeting to membrane;GO:0098693//regulation of synaptic vesicle cycle"	--
ENSG00000176769	0	0.018	0	0	0.022	0.025	0	1	0	0	1	1	TCERG1L	transcription elongation regulator 1 like [Source:HGNC Symbol;Acc:HGNC:23533]	-	-	-	-	GO:0005634//nucleus	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0070063//RNA polymerase binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000176771	8.612	8.308	5.721	4.776	4.154	2.948	1244	1182	624	405	518	330	NCKAP5	NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847]	-	-	-	-	GO:0005575//cellular_component;GO:0035371//microtubule plus-end	-	GO:0001578//microtubule bundle formation;GO:0007019//microtubule depolymerization;GO:0008150//biological_process	--
ENSG00000176774	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB18	MAGE family member B18 [Source:HGNC Symbol;Acc:HGNC:28515]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000176782	0	0	0	0	0	0	0	0	0	0	0	0	DEFB104A	defensin beta 104A [Source:HGNC Symbol;Acc:HGNC:18115]	-	-	-	-	GO:0005576//extracellular region	GO:0042056//chemoattractant activity	GO:0002548//monocyte chemotaxis;GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:1904628//cellular response to phorbol 13-acetate 12-myristate	--
ENSG00000176783	23.719	18.778	22.18	18.01	21.913	23.144	1098	981	775	713	865	856	RUFY1	RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12482	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0017124//SH3 domain binding;GO:0042169//SH2 domain binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0030100//regulation of endocytosis	--
ENSG00000176787	0	0	0	0	0	0	0	0	0	0	0	0	OR52E2	olfactory receptor family 52 subfamily E member 2 [Source:HGNC Symbol;Acc:HGNC:14769]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176788	91.839	87.663	101.892	90.388	87.213	106.309	3413	3287	2820	2509	2761	2898	BASP1	brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030426//growth cone;GO:0031982//vesicle;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000976//transcription cis-regulatory region binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0007356//thorax and anterior abdomen determination;GO:0008406//gonad development;GO:0021762//substantia nigra development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060231//mesenchymal to epithelial transition;GO:0060421//positive regulation of heart growth;GO:0060539//diaphragm development;GO:0072075//metanephric mesenchyme development;GO:0072112//glomerular visceral epithelial cell differentiation;GO:2001076//positive regulation of metanephric ureteric bud development"	--
ENSG00000176797	0	0	0	0	0	0	0	0	0	0	0	0	DEFB103A	defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967]	Organismal Systems;Human Diseases	Immune system;Infectious disease: bacterial	ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K23126;K23126	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0005515//protein binding;GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006952//defense response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:0051873//killing by host of symbiont cells;GO:0060326//cell chemotaxis	--
ENSG00000176798	0	0	0	0	0	0	0	0	0	0	0	0	OR51L1	olfactory receptor family 51 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:14759]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176809	3.753	3.268	3.799	2.36	3.082	2.937	307.1	279.76	224.61	151.04	207.5	165.44	LRRC37A3	leucine rich repeat containing 37 member A3 [Source:HGNC Symbol;Acc:HGNC:32427]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000176834	1.363	1.967	1.486	0.884	1.447	1.27	125	161	114	68	127	96	VSIG10	V-set and immunoglobulin domain containing 10 [Source:HGNC Symbol;Acc:HGNC:26078]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0050839//cell adhesion molecule binding	GO:0098609//cell-cell adhesion	--
ENSG00000176842	0	0	0	0	0.147	0	0	0	0	0	6	0	IRX5	iroquois homeobox 5 [Source:HGNC Symbol;Acc:HGNC:14361]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005499//vitamin D binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007601//visual perception;GO:0008406//gonad development;GO:0030182//neuron differentiation;GO:0048468//cell development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050896//response to stimulus"	Homeobox
ENSG00000176845	42.319	42.106	40.979	49.761	48.01	53.063	1017	1001	752	877	991	926	METRNL	"meteorin like, glial cell differentiation regulator [Source:HGNC Symbol;Acc:HGNC:27584]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0009409//response to cold;GO:0014850//response to muscle activity;GO:0045444//fat cell differentiation;GO:0050728//negative regulation of inflammatory response;GO:0050873//brown fat cell differentiation;GO:0090336//positive regulation of brown fat cell differentiation;GO:0097009//energy homeostasis	--
ENSG00000176853	12.882	10.731	11.562	9.81	9.152	10.735	1391	1106	912	754	771	873	FAM91A1	family with sequence similarity 91 member A1 [Source:HGNC Symbol;Acc:HGNC:26306]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0099041//vesicle tethering to Golgi	--
ENSG00000176871	57.526	57.425	54.09	54.984	51.998	58.714	2807	2722	1964	1946	2045	2113	WSB2	WD repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:19222]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000176884	0.089	0.071	0.036	0.044	0.045	0.019	8	6	2	3	3	1	GRIN1	glutamate ionotropic receptor NMDA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4584]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Substance dependence;Neurodegenerative disease;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208;K05208	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0043083//synaptic cleft;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0097060//synaptic membrane;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015276//ligand-gated ion channel activity;GO:0016594//glycine binding;GO:0016595//glutamate binding;GO:0022849//glutamate-gated calcium ion channel activity;GO:0038023//signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0044877//protein-containing complex binding	"GO:0006811//ion transport;GO:0006812//cation transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0008542//visual learning;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0018964//propylene metabolic process;GO:0019722//calcium-mediated signaling;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0042221//response to chemical;GO:0042391//regulation of membrane potential;GO:0045471//response to ethanol;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051290//protein heterotetramerization;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0055074//calcium ion homeostasis;GO:0060079//excitatory postsynaptic potential;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098976//excitatory chemical synaptic transmission;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904062//regulation of cation transmembrane transport;GO:1905429//response to glycine;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2001056//positive regulation of cysteine-type endopeptidase activity"	--
ENSG00000176887	2.844	2.339	2.32	2.256	2.662	2.709	531	439	320	312	420	368	SOX11	SRY-box transcription factor 11 [Source:HGNC Symbol;Acc:HGNC:11191]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001822//kidney development;GO:0001841//neural tube formation;GO:0002089//lens morphogenesis in camera-type eye;GO:0003151//outflow tract morphogenesis;GO:0003211//cardiac ventricle formation;GO:0003357//noradrenergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014003//oligodendrocyte development;GO:0014009//glial cell proliferation;GO:0014032//neural crest cell development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0021510//spinal cord development;GO:0021782//glial cell development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0035332//positive regulation of hippo signaling;GO:0035914//skeletal muscle cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046887//positive regulation of hormone secretion;GO:0048485//sympathetic nervous system development;GO:0048557//embryonic digestive tract morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0050672//negative regulation of lymphocyte proliferation;GO:0050769//positive regulation of neurogenesis;GO:0060022//hard palate development;GO:0060023//soft palate development;GO:0060174//limb bud formation;GO:0060253//negative regulation of glial cell proliferation;GO:0060412//ventricular septum morphogenesis;GO:0060425//lung morphogenesis;GO:0060548//negative regulation of cell death;GO:0060563//neuroepithelial cell differentiation;GO:0061029//eyelid development in camera-type eye;GO:0061053//somite development;GO:0061303//cornea development in camera-type eye;GO:0061386//closure of optic fissure;GO:2000648//positive regulation of stem cell proliferation;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:2001111//positive regulation of lens epithelial cell proliferation"	HMG
ENSG00000176890	10.317	9.908	7.874	5.035	4.916	4.427	345.18	333.2	194.56	124.77	138.95	107.76	TYMS	thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]	Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Nucleotide metabolism;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism;ko01523//Antifolate resistance;ko00670//One carbon pool by folate	K00560;K00560;K00560;K00560	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003729//mRNA binding;GO:0003824//catalytic activity;GO:0004799//thymidylate synthase activity;GO:0005542//folic acid binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0016741//transferase activity, transferring one-carbon groups;GO:0042803//protein homodimerization activity;GO:1901363//heterocyclic compound binding;GO:1990825//sequence-specific mRNA binding"	GO:0006206//pyrimidine nucleobase metabolic process;GO:0006231//dTMP biosynthetic process;GO:0006235//dTTP biosynthetic process;GO:0006417//regulation of translation;GO:0007568//aging;GO:0007623//circadian rhythm;GO:0009165//nucleotide biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0014070//response to organic cyclic compound;GO:0017148//negative regulation of translation;GO:0019860//uracil metabolic process;GO:0032259//methylation;GO:0032570//response to progesterone;GO:0033189//response to vitamin A;GO:0034097//response to cytokine;GO:0035999//tetrahydrofolate interconversion;GO:0045471//response to ethanol;GO:0046653//tetrahydrofolate metabolic process;GO:0046683//response to organophosphorus;GO:0048589//developmental growth;GO:0051216//cartilage development;GO:0051384//response to glucocorticoid;GO:0051593//response to folic acid;GO:0060574//intestinal epithelial cell maturation;GO:0071897//DNA biosynthetic process;GO:0097421//liver regeneration	--
ENSG00000176893	0	0	0	0	0	0	0	0	0	0	0	0	OR51G2	olfactory receptor family 51 subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:15198]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176894	17.886	16.443	18.324	17.619	16.654	15.66	349	330	265	258	279	223	PXMP2	peroxisomal membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:9716]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13347	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000176895	0	0	0	0	0	0	0	0	0	0	0	0	OR51A7	olfactory receptor family 51 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:15188]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176896	0.896	0.686	1.285	0.734	0.703	0.745	46	41	46	36	36	32	TCEANC	transcription elongation factor A N-terminal and central domain containing [Source:HGNC Symbol;Acc:HGNC:28277]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006351//transcription, DNA-templated"	--
ENSG00000176900	0	0	0	0	0	0	0	0	0	0	0	0	OR51T1	olfactory receptor family 51 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:15205]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176903	57.364	60.887	58.203	62.61	57.481	60.149	3096	3303	2320	2503	2621	2362	PNMA1	PNMA family member 1 [Source:HGNC Symbol;Acc:HGNC:9158]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002437//inflammatory response to antigenic stimulus;GO:0043065//positive regulation of apoptotic process	--
ENSG00000176907	0.237	0.184	0.107	0.178	0.218	0.362	9	7	3	5	7	10	TCIM	transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016607//nuclear speck	GO:0005112//Notch binding;GO:0005515//protein binding	GO:0002264//endothelial cell activation involved in immune response;GO:0006915//apoptotic process;GO:0010739//positive regulation of protein kinase A signaling;GO:0034605//cellular response to heat;GO:0043066//negative regulation of apoptotic process;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045746//negative regulation of Notch signaling pathway;GO:1900020//positive regulation of protein kinase C activity;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902806//regulation of cell cycle G1/S phase transition;GO:1903706//regulation of hemopoiesis	--
ENSG00000176909	0.368	0.793	1.081	1.239	0.559	0.437	14	28	30	24	17	12	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:26689]	-	-	-	-	GO:0005634//nucleus	GO:0003712//transcription coregulator activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010831//positive regulation of myotube differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000176915	15.068	13.788	15.648	12.209	12.209	14.092	1296	1228	1000	771	898	892	ANKLE2	ankyrin repeat and LEM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29101]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding	GO:0007049//cell cycle;GO:0007084//mitotic nuclear membrane reassembly;GO:0007417//central nervous system development;GO:0035307//positive regulation of protein dephosphorylation;GO:0042326//negative regulation of phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0050790//regulation of catalytic activity;GO:0051301//cell division	--
ENSG00000176919	0	0	0	0	0.065	0	0	0	0	0	1	0	C8G	complement C8 gamma chain [Source:HGNC Symbol;Acc:HGNC:1354]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: parasitic;Immune system	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05146//Amoebiasis;ko04610//Complement and coagulation cascades	K03999;K03999;K03999;K03999;K03999	GO:0005576//extracellular region;GO:0005579//membrane attack complex;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001848//complement binding;GO:0005515//protein binding;GO:0019841//retinol binding	"GO:0002376//immune system process;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response"	--
ENSG00000176920	0.161	0.35	0.18	0.382	0.176	0.558	10	13	4	11	7	13	FUT2	fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4013]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K00718;K00718;K00718	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008107//galactoside 2-alpha-L-fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0031127//alpha-(1,2)-fucosyltransferase activity"	GO:0001936//regulation of endothelial cell proliferation;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006664//glycolipid metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0030155//regulation of cell adhesion;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process	--
ENSG00000176922	0	0	0	0	0	0	0	0	0	0	0	0	OR51S1	olfactory receptor family 51 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:15204]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176925	0	0	0	0	0	0	0	0	0	0	0	0	OR51F2	olfactory receptor family 51 subfamily F member 2 [Source:HGNC Symbol;Acc:HGNC:15197]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000176927	0.131	0.036	0.053	0	0	0.033	4	3	2	0	0	2	EFCAB5	EF-hand calcium binding domain 5 [Source:HGNC Symbol;Acc:HGNC:24801]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000176928	0.125	0.086	0.143	0.117	0.068	0.146	13	9	11	9	6	12	GCNT4	glucosaminyl (N-acetyl) transferase 4 [Source:HGNC Symbol;Acc:HGNC:17973]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K09663;K09663	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0002121//inter-male aggressive behavior;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0042403//thyroid hormone metabolic process;GO:0048729//tissue morphogenesis;GO:0048872//homeostasis of number of cells;GO:0060993//kidney morphogenesis	--
ENSG00000176945	0.293	0.127	0.305	0.293	0.414	0.243	19	10	20	13	21	13	MUC20	"mucin 20, cell surface associated [Source:HGNC Symbol;Acc:HGNC:23282]"	-	-	-	-	GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection	GO:0042802//identical protein binding	GO:0048012//hepatocyte growth factor receptor signaling pathway	--
ENSG00000176946	18.95	18.461	20.548	22.294	23.67	20.922	729	701	599	655	740	598	THAP4	THAP domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23187]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0020037//heme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0062213//peroxynitrite isomerase activity;GO:0070026//nitric oxide binding	GO:0006570//tyrosine metabolic process;GO:0042126//nitrate metabolic process	THAP
ENSG00000176953	4.835	4.549	5.352	5.861	5.209	5.141	391	370	298	313	352	308	NFATC2IP	nuclear factor of activated T cells 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:25906]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0016925//protein sumoylation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000176956	0.156	0.102	0.346	0.633	0.121	0.211	3	2	5	9	2	3	LY6H	lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0030550//acetylcholine receptor inhibitor activity;GO:0033130//acetylcholine receptor binding	GO:0007399//nervous system development;GO:0009887//animal organ morphogenesis;GO:0095500//acetylcholine receptor signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000176971	1.588	1.66	1.141	2.012	2.684	1.87	98	103	52	92	140	84	FIBIN	fin bud initiation factor homolog [Source:HGNC Symbol;Acc:HGNC:33747]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus	GO:0003674//molecular_function;GO:0042803//protein homodimerization activity	GO:0008150//biological_process;GO:0010042//response to manganese ion;GO:0070528//protein kinase C signaling;GO:0071548//response to dexamethasone	--
ENSG00000176973	30.897	35.132	33.369	37.537	30.462	34.648	820.57	935	654	742	683	672	FAM89B	family with sequence similarity 89 member B [Source:HGNC Symbol;Acc:HGNC:16708]	-	-	-	-	GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0001222//transcription corepressor binding	GO:0030010//establishment of cell polarity;GO:0030335//positive regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060392//negative regulation of SMAD protein signal transduction	--
ENSG00000176974	23.162	20.915	25.343	22.367	24.443	33.854	992	987	726	790.67	910	904	SHMT1	serine hydroxymethyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10850]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko01523//Antifolate resistance;ko00670//One carbon pool by folate"	K00600;K00600;K00600;K00600;K00600;K00600;K00600	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003824//catalytic activity;GO:0004372//glycine hydroxymethyltransferase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0030170//pyridoxal phosphate binding;GO:0036094//small molecule binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0048027//mRNA 5'-UTR binding;GO:0070905//serine binding"	GO:0006231//dTMP biosynthetic process;GO:0006508//proteolysis;GO:0006544//glycine metabolic process;GO:0006563//L-serine metabolic process;GO:0006565//L-serine catabolic process;GO:0006730//one-carbon metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0016579//protein deubiquitination;GO:0017148//negative regulation of translation;GO:0019264//glycine biosynthetic process from serine;GO:0035999//tetrahydrofolate interconversion;GO:0046653//tetrahydrofolate metabolic process;GO:0046655//folic acid metabolic process;GO:0051289//protein homotetramerization;GO:1904482//cellular response to tetrahydrofolate;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000176978	126.212	135.277	143.318	166.567	155.914	141.824	4164	4485	3471	4044	4333	3402	DPP7	dipeptidyl peptidase 7 [Source:HGNC Symbol;Acc:HGNC:14892]	-	-	-	-	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:1905146//lysosomal protein catabolic process	--
ENSG00000176979	0	0	0	0	0	0	0	0	0	0	0	0	TRIM60	tripartite motif containing 60 [Source:HGNC Symbol;Acc:HGNC:21162]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000176986	33.265	34.688	37.623	34.616	37.353	35.396	2977	3054	2401	2217	2697	2291	SEC24C	"SEC24 homolog C, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10705]"	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05130//Pathogenic Escherichia coli infection;ko04141//Protein processing in endoplasmic reticulum	K14007;K14007	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0070971//endoplasmic reticulum exit site	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001701//in utero embryonic development;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0090110//COPII-coated vesicle cargo loading	--
ENSG00000176988	0	0	0	0	0	0	0	0	0	0	0	0	FMR1NB	FMR1 neighbor [Source:HGNC Symbol;Acc:HGNC:26372]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000176994	9.163	8.591	8.568	8.663	8.914	9.304	1577	1486	1089	1104.33	1296	1165	SMCR8	SMCR8-C9orf72 complex subunit [Source:HGNC Symbol;Acc:HGNC:17921]	Human Diseases;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04140//Autophagy - animal	K23611;K23611;K23611	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0098793//presynapse;GO:0098794//postsynapse;GO:1990316//Atg1/ULK1 kinase complex	GO:0004860//protein kinase inhibitor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0006469//negative regulation of protein kinase activity;GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0010629//negative regulation of gene expression;GO:0016242//negative regulation of macroautophagy;GO:0032008//positive regulation of TOR signaling;GO:0043547//positive regulation of GTPase activity;GO:0045920//negative regulation of exocytosis;GO:0050777//negative regulation of immune response;GO:1901098//positive regulation of autophagosome maturation;GO:1902902//negative regulation of autophagosome assembly;GO:1903432//regulation of TORC1 signaling	--
ENSG00000177000	12.123	14.806	14.295	17.651	15.84	15.472	1358	1461	1136	1323	1388.99	1203	MTHFR	methylenetetrahydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:7436]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko01523//Antifolate resistance;ko00670//One carbon pool by folate	K25004;K25004;K25004	GO:0005829//cytosol;GO:0045202//synapse	GO:0003824//catalytic activity;GO:0004489//methylenetetrahydrofolate reductase (NAD(P)H) activity;GO:0016491//oxidoreductase activity;GO:0044877//protein-containing complex binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0071949//FAD binding;GO:0072341//modified amino acid binding;GO:0106312//methylenetetrahydrofolate reductase NADH activity;GO:0106313//methylenetetrahydrofolate reductase NADPH activity	GO:0001666//response to hypoxia;GO:0001843//neural tube closure;GO:0006555//methionine metabolic process;GO:0008152//metabolic process;GO:0009086//methionine biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0031060//regulation of histone methylation;GO:0033274//response to vitamin B2;GO:0035999//tetrahydrofolate interconversion;GO:0043200//response to amino acid;GO:0046500//S-adenosylmethionine metabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0050667//homocysteine metabolic process;GO:0051593//response to folic acid;GO:0070555//response to interleukin-1;GO:0070828//heterochromatin organization	--
ENSG00000177023	0	0	0	0	0	0	0	0	0	0	0	0	DEFB104B	defensin beta 104B [Source:HGNC Symbol;Acc:HGNC:26165]	-	-	-	-	GO:0005576//extracellular region	GO:0042056//chemoattractant activity	GO:0002548//monocyte chemotaxis;GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:1904628//cellular response to phorbol 13-acetate 12-myristate	--
ENSG00000177025	0.053	0	0.071	0	0.312	0.072	1	0	1	0	5	1	C19orf18	chromosome 19 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:28642]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000177030	36.777	35.082	42.766	41.387	42.425	41.453	1491	1467	1291	1285	1510	1230	DEAF1	DEAF1 transcription factor [Source:HGNC Symbol;Acc:HGNC:14677]	-	-	-	-	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001843//neural tube closure;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007399//nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048706//embryonic skeletal system development"	SAND
ENSG00000177034	2.522	2.338	2.153	2.074	1.734	2.432	378	306	217	215	226	235	MTX3	metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]	-	-	-	-	GO:0001401//SAM complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0140275//MIB complex	GO:0003674//molecular_function	GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization;GO:0015031//protein transport	--
ENSG00000177042	7.087	6.315	5.883	6.652	6.132	6.843	196	181	125	138	152	141	TMEM80	transmembrane protein 80 [Source:HGNC Symbol;Acc:HGNC:27453]	-	-	-	-	GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0042995//cell projection	GO:0005515//protein binding	GO:1905515//non-motile cilium assembly	--
ENSG00000177045	10.344	9.635	9.867	8.567	11.745	10.862	567	592	438	387	578	446	SIX5	SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0002088//lens development in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007286//spermatid development;GO:0008285//negative regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation"	Homeobox
ENSG00000177047	0	0	0	0	0	0	0	0	0	0	0	0	IFNW1	interferon omega 1 [Source:HGNC Symbol;Acc:HGNC:5448]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04622//RIG-I-like receptor signaling pathway	K05440;K05440;K05440	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000177051	3.921	4.703	5.077	4.515	6.044	5.655	216	199	152	176	240	189	FBXO46	F-box protein 46 [Source:HGNC Symbol;Acc:HGNC:25069]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000177054	7.045	6.509	7.244	6.276	6.125	6.775	351	325	267	232	255	246	ZDHHC13	zinc finger DHHC-type palmitoyltransferase 13 [Source:HGNC Symbol;Acc:HGNC:18413]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0018345//protein palmitoylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000177058	13.718	10.629	12.784	8.031	11.019	12.27	416	354	315	262	335	321	SLC38A9	solute carrier family 38 member 9 [Source:HGNC Symbol;Acc:HGNC:26907]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K14995	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0071986//Ragulator complex;GO:1905103//integral component of lysosomal membrane	GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0046872//metal ion binding;GO:0061459//L-arginine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015711//organic anion transport;GO:0015803//branched-chain amino acid transport;GO:0015804//neutral amino acid transport;GO:0015807//L-amino acid transport;GO:0032008//positive regulation of TOR signaling;GO:0071230//cellular response to amino acid stimulus;GO:0098655//cation transmembrane transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:1903826//arginine transmembrane transport	--
ENSG00000177076	0.452	0.156	0.306	0.305	0.226	0.406	26	9	13	13	11	17	ACER2	alkaline ceramidase 2 [Source:HGNC Symbol;Acc:HGNC:23675]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K01441;K01441;K01441	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	"GO:0016787//hydrolase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0046872//metal ion binding;GO:0071633//dihydroceramidase activity;GO:0102121//ceramidase activity"	"GO:0001953//negative regulation of cell-matrix adhesion;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell population proliferation;GO:0010506//regulation of autophagy;GO:0010942//positive regulation of cell death;GO:0030148//sphingolipid biosynthetic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032526//response to retinoic acid;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0042981//regulation of apoptotic process;GO:0046512//sphingosine biosynthetic process;GO:0046514//ceramide catabolic process;GO:0071466//cellular response to xenobiotic stimulus;GO:0090285//negative regulation of protein glycosylation in Golgi"	--
ENSG00000177082	4.922	4.793	5.492	4.353	5.5	5.552	363	404	257.75	294	328	252	WDR73	WD repeat domain 73 [Source:HGNC Symbol;Acc:HGNC:25928]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032154//cleavage furrow	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006997//nucleus organization;GO:0031122//cytoplasmic microtubule organization;GO:0043066//negative regulation of apoptotic process	--
ENSG00000177084	3.918	4.135	5.189	3.524	3.096	3.608	619	649	482	379	427	413	POLE	"DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177]"	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03030//DNA replication;ko03410//Base excision repair	K02324;K02324;K02324	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0008622//epsilon DNA polymerase complex	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006272//leading strand elongation;GO:0006281//DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006974//cellular response to DNA damage stimulus;GO:0044260//cellular macromolecule metabolic process;GO:0045004//DNA replication proofreading;GO:0048568//embryonic organ development;GO:0071897//DNA biosynthetic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000177096	3.283	3.777	3.998	3.642	3.764	3.547	159	175	143	118	154	125	PHETA2	PH domain containing endocytic trafficking adaptor 2 [Source:HGNC Symbol;Acc:HGNC:27161]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	"GO:0001881//receptor recycling;GO:0007032//endosome organization;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000177098	0.322	0.192	0.407	0.45	0.432	0.458	30	18	28	31	34	31	SCN4B	sodium voltage-gated channel beta subunit 4 [Source:HGNC Symbol;Acc:HGNC:10592]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04848	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0010765//positive regulation of sodium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0060048//cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086016//AV node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000177103	0.119	0.197	0.268	0.364	0.25	0.272	16	28	25	36	30	25	DSCAML1	DS cell adhesion molecule like 1 [Source:HGNC Symbol;Acc:HGNC:14656]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0045202//synapse	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0098632//cell-cell adhesion mediator activity	GO:0001709//cell fate determination;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0009953//dorsal/ventral pattern formation;GO:0048704//embryonic skeletal system morphogenesis;GO:0070593//dendrite self-avoidance	--
ENSG00000177105	9.307	8.998	10.062	11.308	12.338	12.945	250	241	199	225	280	253	RHOG	ras homolog family member G [Source:HGNC Symbol;Acc:HGNC:672]	Human Diseases;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial	ko05132//Salmonella infection;ko05135//Yersinia infection;ko05100//Bacterial invasion of epithelial cells	K07863;K07863;K07863	GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding	"GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0008045//motor neuron axon guidance;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043652//engulfment of apoptotic cell;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060326//cell chemotaxis;GO:0090630//activation of GTPase activity;GO:1900027//regulation of ruffle assembly;GO:1902622//regulation of neutrophil migration;GO:1903078//positive regulation of protein localization to plasma membrane"	--
ENSG00000177106	23.237	27.077	21.23	14.444	15.18	15.928	953	1069	654	456	591	515	EPS8L2	EPS8 like 2 [Source:HGNC Symbol;Acc:HGNC:21296]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0032421//stereocilium bundle;GO:0032426//stereocilium tip;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007266//Rho protein signal transduction;GO:0007605//sensory perception of sound;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000177108	0	0	0.019	0	0	0	0	0	1	0	0	0	ZDHHC22	zinc finger DHHC-type palmitoyltransferase 22 [Source:HGNC Symbol;Acc:HGNC:20106]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0072659//protein localization to plasma membrane	--
ENSG00000177119	18.334	15.229	15.612	13.755	16.208	16.516	2158	1811	1380	1193	1533	1443	ANO6	anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005227//calcium activated cation channel activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity	"GO:0002407//dendritic cell chemotaxis;GO:0002543//activation of blood coagulation via clotting cascade;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006821//chloride transport;GO:0006869//lipid transport;GO:0007596//blood coagulation;GO:0017121//plasma membrane phospholipid scrambling;GO:0030501//positive regulation of bone mineralization;GO:0032060//bleb assembly;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0034767//positive regulation of ion transmembrane transport;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0035725//sodium ion transmembrane transport;GO:0043065//positive regulation of apoptotic process;GO:0045794//negative regulation of cell volume;GO:0046931//pore complex assembly;GO:0055085//transmembrane transport;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0061588//calcium activated phospholipid scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling;GO:0070588//calcium ion transmembrane transport;GO:0090026//positive regulation of monocyte chemotaxis;GO:0097045//phosphatidylserine exposure on blood platelet;GO:1902476//chloride transmembrane transport;GO:1903766//positive regulation of potassium ion export across plasma membrane;GO:2000353//positive regulation of endothelial cell apoptotic process"	--
ENSG00000177125	3.163	2.923	2.722	2.428	2.707	3.274	433	402	275	246	313	326	ZBTB34	zinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGNC:31446]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	ZBTB
ENSG00000177138	0	0	0	0	0	0	0	0	0	0	0	0	FAM9B	family with sequence similarity 9 member B [Source:HGNC Symbol;Acc:HGNC:18404]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	GO:0007286//spermatid development;GO:0051321//meiotic cell cycle	--
ENSG00000177143	0.056	0.028	0	0	0	0	2	1	0	0	0	0	CETN1	centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0032795//heterotrimeric G-protein binding;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0006289//nucleotide-excision repair;GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0034605//cellular response to heat;GO:0051301//cell division	--
ENSG00000177144	2.754	2.001	2.211	1.605	1.931	1.692	208.05	151.95	123.36	89.82	123.25	93	NUDT4B	nudix hydrolase 4B [Source:HGNC Symbol;Acc:HGNC:18012]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000298//endopolyphosphatase activity;GO:0003723//RNA binding;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity	GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	--
ENSG00000177150	3.652	2.807	2.158	5.034	3.138	3.862	177	171.25	133	147	154	169	FAM210A	family with sequence similarity 210 member A [Source:HGNC Symbol;Acc:HGNC:28346]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000177151	0	0	0	0	0	0	0	0	0	0	0	0	OR2T35	olfactory receptor family 2 subfamily T member 35 [Source:HGNC Symbol;Acc:HGNC:31257]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177156	69.905	68.193	69.766	80.799	74.871	77.703	1755	1718	1294	1503	1589	1421	TALDO1	transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00616;K00616;K00616;K00616	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004801//transaldolase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030246//carbohydrate binding;GO:0048029//monosaccharide binding	"GO:0005975//carbohydrate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019682//glyceraldehyde-3-phosphate metabolic process"	--
ENSG00000177169	17.375	19.206	15.847	15.128	18.25	16.397	1918	2131	1292	1237	1702	1317	ULK1	unc-51 like autophagy activating kinase 1 [Source:HGNC Symbol;Acc:HGNC:12558]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Transport and catabolism;Neurodegenerative disease;Signal transduction;Aging;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04137//Mitophagy - animal	K21357;K21357;K21357;K21357;K21357;K21357;K21357;K21357;K21357;K21357	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005776//autophagosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0030424//axon;GO:0034045//phagophore assembly site membrane;GO:0055037//recycling endosome;GO:0097629//extrinsic component of omegasome membrane;GO:0097632//extrinsic component of phagophore assembly site membrane;GO:0097635//extrinsic component of autophagosome membrane;GO:1990316//Atg1/ULK1 kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0051020//GTPase binding;GO:0106310//protein serine kinase activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006468//protein phosphorylation;GO:0006914//autophagy;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0008104//protein localization;GO:0008285//negative regulation of cell population proliferation;GO:0010508//positive regulation of autophagy;GO:0016236//macroautophagy;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0031102//neuron projection regeneration;GO:0031175//neuron projection development;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031669//cellular response to nutrient levels;GO:0034727//piecemeal microautophagy of the nucleus;GO:0042594//response to starvation;GO:0044805//late nucleophagy;GO:0046777//protein autophosphorylation;GO:0048671//negative regulation of collateral sprouting;GO:0048675//axon extension;GO:0061709//reticulophagy;GO:1903059//regulation of protein lipidation;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000177174	0	0	0	0	0	0	0	0	0	0	0	0	OR14C36	olfactory receptor family 14 subfamily C member 36 [Source:HGNC Symbol;Acc:HGNC:15026]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177181	0.893	0.83	0.617	1.155	0.7	1.055	196	183	100	130	118	140	RIMKLA	ribosomal modification protein rimK like family member A [Source:HGNC Symbol;Acc:HGNC:28725]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism"	K18311;K18311	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046872//metal ion binding;GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity"	GO:0006464//cellular protein modification process;GO:0009064//glutamine family amino acid metabolic process	--
ENSG00000177182	0.134	0.038	0	0.106	0.07	0.139	2.11	2.3	0	5.67	4.24	4.54	CLVS1	clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139]	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0007040//lysosome organization	--
ENSG00000177186	0	0	0	0	0	0	0	0	0	0	0	0	OR2M7	olfactory receptor family 2 subfamily M member 7 [Source:HGNC Symbol;Acc:HGNC:19594]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177189	8.065	6.285	6.987	4.976	4.675	6.042	913	679	511	423	473	487	RPS6KA3	ribosomal protein S6 kinase A3 [Source:HGNC Symbol;Acc:HGNC:10432]	Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Environmental adaptation;Infectious disease: bacterial;Cancer: overview;Signal transduction;Cell growth and death;Nervous system;Endocrine system;Endocrine and metabolic disease;Nervous system	ko04010//MAPK signaling pathway;ko04714//Thermogenesis;ko05135//Yersinia infection;ko05207//Chemical carcinogenesis - receptor activation;ko04150//mTOR signaling pathway;ko04114//Oocyte meiosis;ko04722//Neurotrophin signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko04720//Long-term potentiation	K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373;K04373	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0045202//synapse	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001501//skeletal system development;GO:0002224//toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007417//central nervous system development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0032496//response to lipopolysaccharide;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043555//regulation of translation in response to stress;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000177191	0.719	0.901	0.381	0.515	0.534	0.352	23	29	9	13	16	9	B3GNT8	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:24139]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016262//protein N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity"	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing;GO:0030311//poly-N-acetyllactosamine biosynthetic process	--
ENSG00000177192	2.415	4.292	3.665	3.744	3.454	3	71	109	67	81	84	61	PUS1	pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000049//tRNA binding;GO:0002153//steroid receptor RNA activator RNA binding;GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity;GO:0016853//isomerase activity;GO:0106029//tRNA pseudouridine synthase activity	GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing;GO:0009451//RNA modification;GO:0031119//tRNA pseudouridine synthesis;GO:0070902//mitochondrial tRNA pseudouridine synthesis;GO:1990481//mRNA pseudouridine synthesis	--
ENSG00000177200	5.496	3.037	4.065	2.556	2.315	4.174	1130	638	394	331	441	478	CHD9	chromodomain helicase DNA binding protein 9 [Source:HGNC Symbol;Acc:HGNC:25701]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0032508//DNA duplex unwinding	--
ENSG00000177201	0	0	0	0	0	0	0	0	0	0	0	0	OR2T12	olfactory receptor family 2 subfamily T member 12 [Source:HGNC Symbol;Acc:HGNC:19592]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177202	0	0	0	0	0	0	0	0	0	0	0	0	SPACA4	sperm acrosome associated 4 [Source:HGNC Symbol;Acc:HGNC:16441]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0007155//cell adhesion	--
ENSG00000177212	0	0	0	0.061	0	0	0	0	0	1	0	0	OR2T33	olfactory receptor family 2 subfamily T member 33 [Source:HGNC Symbol;Acc:HGNC:31255]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177225	19.261	20.137	26.727	22.004	23.132	21.403	996	1181	996	947	967	930	GATD1	glutamine amidotransferase class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000177238	0.006	0	0	0.046	0.007	0.042	1	0	0	2	1	1	TRIM72	tripartite motif containing 72 [Source:HGNC Symbol;Acc:HGNC:32671]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042383//sarcolemma	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0001778//plasma membrane repair;GO:0003012//muscle system process;GO:0006887//exocytosis;GO:0007517//muscle organ development;GO:0010832//negative regulation of myotube differentiation;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000177239	27.946	31.759	30.699	31.948	31.108	28.734	1607	1820	1291	1356	1512	1198	MAN1B1	mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K23741;K23741;K23741;K23741	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0044322//endoplasmic reticulum quality control compartment;GO:1903561//extracellular vesicle	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0019082//viral protein processing;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036508//protein alpha-1,2-demannosylation;GO:0036509//trimming of terminal mannose on B branch;GO:0036510//trimming of terminal mannose on C branch;GO:0036511//trimming of first mannose on A branch;GO:0036512//trimming of second mannose on A branch;GO:1904380//endoplasmic reticulum mannose trimming;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway"	--
ENSG00000177243	0	0	0	0	0	0	0	0	0	0	0	0	DEFB103B	defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702]	Organismal Systems;Human Diseases	Immune system;Infectious disease: bacterial	ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K23126;K23126	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0005515//protein binding;GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006952//defense response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:0051873//killing by host of symbiont cells;GO:0060326//cell chemotaxis	--
ENSG00000177257	0	0	0	0	0	0	0	0	0	0	0	0	DEFB4B	defensin beta 4B [Source:HGNC Symbol;Acc:HGNC:30193]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Immune system	ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection;ko04657//IL-17 signaling pathway	K21100;K21100;K21100	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen	GO:0005515//protein binding;GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000177272	0	0	0	0	0	0	0	0	0	0	0	0	KCNA3	potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0044305//calyx of Held;GO:0045121//membrane raft;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015271//outward rectifier potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000177275	0	0	0	0	0.03	0	0	0	0	0	1	0	OR2AJ1	olfactory receptor family 2 subfamily AJ member 1 [Source:HGNC Symbol;Acc:HGNC:15001]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177283	35.2	40.752	39.553	27.417	30.294	24.345	2957	3441	2454	1706	2150	1488	FZD8	frizzled class receptor 8 [Source:HGNC Symbol;Acc:HGNC:4046]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375;K02375	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990851//Wnt-Frizzled-LRP5/6 complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0042813//Wnt-activated receptor activity	GO:0001525//angiogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0033077//T cell differentiation in thymus;GO:0043507//positive regulation of JUN kinase activity;GO:0060070//canonical Wnt signaling pathway	--
ENSG00000177291	0.029	0.029	0	0.079	0	0	1	1	0	2	0	0	GJD4	gap junction protein delta 4 [Source:HGNC Symbol;Acc:HGNC:23296]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0014717//regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0055085//transmembrane transport	--
ENSG00000177294	0	0	0	0	0	0	0	0	0	0	0	0	FBXO39	F-box protein 39 [Source:HGNC Symbol;Acc:HGNC:28565]	-	-	-	-	GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000177300	0	0	0	0	0	0	0	0	0	0	0	0	CLDN22	claudin 22 [Source:HGNC Symbol;Acc:HGNC:2044]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000177301	0.165	0.17	0.113	0.188	0.222	0.063	18	16	7	17	15	9	KCNA2	potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0031258//lamellipodium membrane;GO:0032809//neuronal cell body membrane;GO:0033010//paranodal junction;GO:0034705//potassium channel complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043194//axon initial segment;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0044224//juxtaparanode region of axon;GO:0044305//calyx of Held;GO:0045202//synapse;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015271//outward rectifier potassium channel activity;GO:0019894//kinesin binding	"GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0014059//regulation of dopamine secretion;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0021633//optic nerve structural organization;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0045188//regulation of circadian sleep/wake cycle, non-REM sleep;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0097623//potassium ion export across plasma membrane"	--
ENSG00000177302	11.282	8.94	10.24	12.185	10.816	9.996	900	880	685	670	729	653	TOP3A	DNA topoisomerase III alpha [Source:HGNC Symbol;Acc:HGNC:11992]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K03165;K03165	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016605//PML body;GO:0031422//RecQ family helicase-topoisomerase III complex	"GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003916//DNA topoisomerase activity;GO:0003917//DNA topoisomerase type I (single strand cut, ATP-independent) activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding"	GO:0000724//double-strand break repair via homologous recombination;GO:0006265//DNA topological change;GO:0032042//mitochondrial DNA metabolic process;GO:0051304//chromosome separation;GO:0051321//meiotic cell cycle;GO:0071139//resolution of recombination intermediates	--
ENSG00000177303	6.295	6.485	8.23	6.366	7.166	11.566	553	581	508	486	624	549.33	CASKIN2	CASK interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18200]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000177311	42.111	24.304	33.068	19.125	21.547	29.477	3124	2412	1771	1155	1568	1772	ZBTB38	zinc finger and BTB domain containing 38 [Source:HGNC Symbol;Acc:HGNC:26636]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0072562//blood microparticle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	"GO:0006275//regulation of DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	ZBTB
ENSG00000177324	0	0	0	0	0	0	0	0	0	0	0	0	BEND2	BEN domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28509]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000177352	11.521	11.596	12.429	14.645	12.649	12.209	428	433	341	403	397	330	CCDC71	coiled-coil domain containing 71 [Source:HGNC Symbol;Acc:HGNC:25760]	-	-	-	-	-	-	-	--
ENSG00000177354	0	0	0	0	0.011	0	0	0	0	0	1	0	C10orf71	chromosome 10 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:26973]	-	-	-	-	GO:0005737//cytoplasm;GO:0030018//Z disc	GO:0005515//protein binding	GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000177363	0.479	0.672	0.502	0.559	0.49	0.389	22	31	17	19	19	13	LRRN4CL	LRRN4 C-terminal like [Source:HGNC Symbol;Acc:HGNC:33724]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000177370	6.092	5.638	6.38	6.852	6.205	6.06	402.06	374.03	311	335	346	291.03	TIMM22	translocase of inner mitochondrial membrane 22 [Source:HGNC Symbol;Acc:HGNC:17317]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042721//TIM22 mitochondrial import inner membrane insertion complex	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0030943//mitochondrion targeting sequence binding;GO:0140318//protein transporter activity	GO:0015031//protein transport;GO:0045039//protein insertion into mitochondrial inner membrane;GO:0071806//protein transmembrane transport	--
ENSG00000177374	0.078	0.238	0.155	0.117	0.124	0.272	10.8	19.32	10.41	12.03	10.7	14.04	HIC1	HIC ZBTB transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:4909]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator"	ZBTB
ENSG00000177380	0.707	0.603	1.628	1.351	0.841	0.827	46	33	59	46	33	45	PPFIA3	PTPRF interacting protein alpha 3 [Source:HGNC Symbol;Acc:HGNC:9247]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098875//epididymosome;GO:0098978//glutamatergic synapse	GO:0005515//protein binding	GO:0007269//neurotransmitter secretion;GO:0016079//synaptic vesicle exocytosis;GO:0016081//synaptic vesicle docking;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0050808//synapse organization	--
ENSG00000177383	26.019	23.63	22.834	23.991	25.06	25.242	918	838	595	627	747	648	MAGEF1	MAGE family member F1 [Source:HGNC Symbol;Acc:HGNC:29639]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000177398	1.288	2.124	1.3	1.017	1.148	0.638	136	217	99	80	100	47	UMODL1	uromodulin like 1 [Source:HGNC Symbol;Acc:HGNC:12560]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0007338//single fertilization;GO:0010468//regulation of gene expression;GO:0042981//regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0048609//multicellular organismal reproductive process;GO:0052547//regulation of peptidase activity;GO:0060612//adipose tissue development;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:1990266//neutrophil migration;GO:2000354//regulation of ovarian follicle development	--
ENSG00000177409	0.225	0.017	0.186	0.079	0.04	0	6	2	5	7	5	0	SAMD9L	sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome	GO:0005515//protein binding	-	--
ENSG00000177414	0	0	0.172	0	0	0.117	0	0	3	0	0	2	UBE2U	ubiquitin conjugating enzyme E2 U [Source:HGNC Symbol;Acc:HGNC:28559]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10584	GO:0033503//HULC complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000177425	8.37	9.484	7.765	9.105	6.824	9.282	1455	1188	872	802	935	1071	PAWR	pro-apoptotic WT1 regulator [Source:HGNC Symbol;Acc:HGNC:8614]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton	GO:0003714//transcription corepressor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0043522//leucine zipper domain binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030889//negative regulation of B cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051017//actin filament bundle assembly;GO:0097190//apoptotic signaling pathway;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:2000774//positive regulation of cellular senescence	--
ENSG00000177426	18.166	17.43	20.472	21.329	16.554	21.525	387	410	360	344	331	348	TGIF1	TGFB induced factor homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11776]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K19383	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000177427	9.847	11.473	14.106	14.289	11.25	10.747	371	376	338	342	368	284	MIEF2	mitochondrial elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:17920]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0007005//mitochondrion organization;GO:0010821//regulation of mitochondrion organization;GO:0090141//positive regulation of mitochondrial fission;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000177432	11.141	10.083	10.42	10.186	8.841	9.471	443	403	306	300	297	274	NAP1L5	nucleosome assembly protein 1 like 5 [Source:HGNC Symbol;Acc:HGNC:19968]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly	--
ENSG00000177453	0.73	0.581	0.621	0.563	0.797	0.63	35	28	22	20	33	22	NIM1K	NIM1 serine/threonine protein kinase [Source:HGNC Symbol;Acc:HGNC:28646]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation	--
ENSG00000177455	0	0	0	0	0	0	0	0	0	0	0	0	CD19	CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Infectious disease: viral;Immune system;Immune system;Immune disease	ko04151//PI3K-Akt signaling pathway;ko05169//Epstein-Barr virus infection;ko04640//Hematopoietic cell lineage;ko04662//B cell receptor signaling pathway;ko05340//Primary immunodeficiency	K06465;K06465;K06465;K06465;K06465	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	-	GO:0001923//B-1 B cell differentiation;GO:0002250//adaptive immune response;GO:0002322//B cell proliferation involved in immune response;GO:0002376//immune system process;GO:0016064//immunoglobulin mediated immune response;GO:0019724//B cell mediated immunity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050855//regulation of B cell receptor signaling pathway;GO:0050864//regulation of B cell activation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol	--
ENSG00000177459	23.665	23.857	21.542	27.654	30.692	31.417	710	710	493	611	775	692	ERICH5	glutamate rich 5 [Source:HGNC Symbol;Acc:HGNC:26823]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000177462	0	0	0	0	0	0	0	0	0	0	0	0	OR2T8	olfactory receptor family 2 subfamily T member 8 [Source:HGNC Symbol;Acc:HGNC:15020]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177463	11.586	9.557	8.735	5.209	8.859	9.107	1315.05	1166.96	782.95	550.46	885.58	791.72	NR2C2	nuclear receptor subfamily 2 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7972]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0040019//positive regulation of embryonic development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development"	RXR-like
ENSG00000177464	0	0	0	0	0	0	0	0	0	0	0	0	GPR4	G protein-coupled receptor 4 [Source:HGNC Symbol;Acc:HGNC:4497]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0010447//response to acidic pH;GO:0016525//negative regulation of angiogenesis;GO:0030155//regulation of cell adhesion;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043114//regulation of vascular permeability;GO:0050729//positive regulation of inflammatory response;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060055//angiogenesis involved in wound healing;GO:0072144//glomerular mesangial cell development	--
ENSG00000177465	0.296	0.753	0.49	0.355	0.312	0.407	9	23	11	8	8	9	ACOT4	acyl-CoA thioesterase 4 [Source:HGNC Symbol;Acc:HGNC:19748]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04913//Ovarian steroidogenesis;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K01068;K01068;K01068;K01068	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0004778//succinyl-CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0044466//glutaryl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006104//succinyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0032788//saturated monocarboxylic acid metabolic process;GO:0032789//unsaturated monocarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0043649//dicarboxylic acid catabolic process;GO:0046459//short-chain fatty acid metabolic process	--
ENSG00000177468	0	0	0	0	0	0	0	0	0	0	0	0	OLIG3	oligodendrocyte transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:18003]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021522//spinal cord motor neuron differentiation;GO:0030182//neuron differentiation;GO:0097476//spinal cord motor neuron migration"	bHLH
ENSG00000177469	60.622	61.911	62.498	60.145	60.629	62.437	4489	4608	3418	3299	3793	3364	CAVIN1	caveolae associated protein 1 [Source:HGNC Symbol;Acc:HGNC:9688]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0042134//rRNA primary transcript binding;GO:0042802//identical protein binding	"GO:0006353//DNA-templated transcription, termination;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0009303//rRNA transcription;GO:0009306//protein secretion;GO:2000147//positive regulation of cell motility"	--
ENSG00000177476	0	0	0	0	0	0	0	0	0	0	0	0	OR2G3	olfactory receptor family 2 subfamily G member 3 [Source:HGNC Symbol;Acc:HGNC:15008]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177479	20.905	20.616	22.62	20.499	22.038	27.876	1423	1388	1066	1057	1284	1228	ARIH2	ariadne RBR E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:690]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031466//Cul5-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048588//developmental cell growth;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0071425//hematopoietic stem cell proliferation;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000177483	0.042	0.014	0	0	0.017	0.019	3	1	0	0	1	1	RBM44	RNA binding motif protein 44 [Source:HGNC Symbol;Acc:HGNC:24756]	-	-	-	-	GO:0005737//cytoplasm;GO:0045171//intercellular bridge	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0042803//protein homodimerization activity	-	--
ENSG00000177485	9.852	8.376	8.694	7.582	7.136	8.157	1065	910	694	607	652	642	ZBTB33	zinc finger and BTB domain containing 33 [Source:HGNC Symbol;Acc:HGNC:16682]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008327//methyl-CpG binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016055//Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0045892//negative regulation of transcription, DNA-templated"	ZBTB
ENSG00000177489	0	0	0	0	0	0	0	0	0	0	0	0	OR2G2	olfactory receptor family 2 subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:15007]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177494	0	0.022	0	0.029	0	0.06	0	1	0	1	0	2	ZBED2	zinc finger BED-type containing 2 [Source:HGNC Symbol;Acc:HGNC:20710]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045618//positive regulation of keratinocyte differentiation	zf-BED
ENSG00000177504	0	0	0	0	0	0	0	0	0	0	0	0	VCX2	variable charge X-linked 2 [Source:HGNC Symbol;Acc:HGNC:18158]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0007420//brain development;GO:0008150//biological_process	--
ENSG00000177508	0.147	0.28	0.025	0.223	0.065	0.025	8	7	1	9	3	1	IRX3	iroquois homeobox 3 [Source:HGNC Symbol;Acc:HGNC:14360]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001656//metanephros development;GO:0003165//Purkinje myocyte development;GO:0003167//atrioventricular bundle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007498//mesoderm development;GO:0030182//neuron differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0060932//His-Purkinje system cell differentiation;GO:0072047//proximal/distal pattern formation involved in nephron development;GO:0072086//specification of loop of Henle identity;GO:0097009//energy homeostasis;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1903598//positive regulation of gap junction assembly"	Homeobox
ENSG00000177511	0	0	0	0	0	0	0	0	0	0	0	0	ST8SIA3	"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:14269]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0033691//sialic acid binding;GO:0042802//identical protein binding"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006688//glycosphingolipid biosynthetic process;GO:0009100//glycoprotein metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation;GO:1990743//protein sialylation	--
ENSG00000177519	24.292	25.951	26.661	32.292	29.514	33.944	718	771	582	707	737	730	RPRM	"reprimo, TP53 dependent G2 arrest mediator homolog [Source:HGNC Symbol;Acc:HGNC:24201]"	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K10128	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007346//regulation of mitotic cell cycle;GO:0051726//regulation of cell cycle	--
ENSG00000177535	0	0	0	0.043	0	0	0	0	0	3	0	0	OR2B11	olfactory receptor family 2 subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:31249]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177542	4.768	6.012	5.529	7.701	5.913	5.112	266	258	193.68	227	261	203	SLC25A22	solute carrier family 25 member 22 [Source:HGNC Symbol;Acc:HGNC:19954]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005280//amino acid:proton symporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015810//aspartate transmembrane transport;GO:0015813//L-glutamate transmembrane transport;GO:0043490//malate-aspartate shuttle;GO:0055085//transmembrane transport;GO:0070778//L-aspartate transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000177548	5.301	4.825	5.477	6.491	6.166	6.167	249	203	192	218	221	205	RABEP2	"rabaptin, RAB GTPase binding effector protein 2 [Source:HGNC Symbol;Acc:HGNC:24817]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0050790//regulation of catalytic activity;GO:1902017//regulation of cilium assembly	--
ENSG00000177551	0	0	0	0	0	0	0	0	0	0	0	0	NHLH2	nescient helix-loop-helix 2 [Source:HGNC Symbol;Acc:HGNC:7818]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007417//central nervous system development;GO:0007422//peripheral nervous system development;GO:0007617//mating behavior;GO:0008584//male gonad development;GO:0021535//cell migration in hindbrain;GO:0021888//hypothalamus gonadotrophin-releasing hormone neuron development;GO:0030154//cell differentiation;GO:0042698//ovulation cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060179//male mating behavior	bHLH
ENSG00000177556	47.267	43.251	51.555	47.492	43.183	49.117	476	432	378	354	366	358	ATOX1	antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K07213	GO:0005829//cytosol	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016530//metallochaperone activity;GO:0016531//copper chaperone activity;GO:0032767//copper-dependent protein binding;GO:0046872//metal ion binding;GO:1903136//cuprous ion binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0006979//response to oxidative stress	--
ENSG00000177558	0	0	0	0	0	0	0	0	0	0	0	0	FAM187B	family with sequence similarity 187 member B [Source:HGNC Symbol;Acc:HGNC:26366]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000177565	14.939	12.841	12.474	8.118	10.509	14.056	1665	1425	931	746	949	939	TBL1XR1	TBL1X receptor 1 [Source:HGNC Symbol;Acc:HGNC:29529]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04508	GO:0000118//histone deacetylase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0072686//mitotic spindle	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0042393//histone binding;GO:0047485//protein N-terminus binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001835//blastocyst hatching;GO:0002021//response to dietary excess;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0016042//lipid catabolic process;GO:0016575//histone deacetylation;GO:0035264//multicellular organism growth;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050872//white fat cell differentiation;GO:0060612//adipose tissue development;GO:0060613//fat pad development;GO:0090207//regulation of triglyceride metabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway"	--
ENSG00000177570	6.397	6.039	5.666	5.439	6.633	6.128	525.34	489.67	319.85	324.7	411.9	347.65	SAMD12	sterile alpha motif domain containing 12 [Source:HGNC Symbol;Acc:HGNC:31750]	-	-	-	-	GO:0005575//cellular_component;GO:0009898//cytoplasmic side of plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008150//biological_process	--
ENSG00000177575	0	0	0	0	0.112	0	0	0	0	0	8	0	CD163	CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030666//endocytic vesicle membrane	GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0097110//scaffold protein binding	GO:0006897//endocytosis;GO:0006953//acute-phase response;GO:0006954//inflammatory response	--
ENSG00000177576	5.041	6.544	6.582	5.431	6.465	6.995	478.9	530.33	465.14	460.18	505.93	417.87	C18orf32	chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet	GO:0005515//protein binding	GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000177595	1.284	1.153	1.161	1.554	1.525	1.571	85	81	63	78	76	78	PIDD1	p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491]	Environmental Information Processing;Cellular Processes;Cellular Processes	Signal transduction;Cell growth and death;Cell growth and death	ko04064//NF-kappa B signaling pathway;ko04210//Apoptosis;ko04115//p53 signaling pathway	K10130;K10130;K10130	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:1905369//endopeptidase complex	GO:0004175//endopeptidase activity;GO:0005123//death receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007165//signal transduction;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0016540//protein autoprocessing;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway"	--
ENSG00000177599	1.873	1.432	0.927	0.901	1.126	0.711	80	64	41	40	57	31	ZNF491	zinc finger protein 491 [Source:HGNC Symbol;Acc:HGNC:23706]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000177600	306.968	289.18	294.512	376.354	277.476	288.507	2942	2786	2085	2668	2247	2012	RPLP2	ribosomal protein lateral stalk subunit P2 [Source:HGNC Symbol;Acc:HGNC:10377]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02943;K02943	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular exosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0002182//cytoplasmic translational elongation;GO:0006412//translation;GO:0006414//translational elongation	--
ENSG00000177602	0.431	0.583	0.28	0.14	0.224	0.308	25	34	12	6	11	13	HASPIN	histone H3 associated protein kinase [Source:HGNC Symbol;Acc:HGNC:19682]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0072354//histone kinase activity (H3-T3 specific);GO:0106310//protein serine kinase activity	"GO:0000278//mitotic cell cycle;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0071459//protein localization to chromosome, centromeric region;GO:2000751//histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore"	--
ENSG00000177606	4.266	3.717	4.176	4.587	4.298	4.368	264	227	191	210	221	194	JUN	"Jun proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6204]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Cellular community - eukaryotes;Signal transduction;Endocrine and metabolic disease;Infectious disease: viral;Immune disease;Endocrine system;Immune system;Cancer: specific types;Infectious disease: viral;Infectious disease: parasitic;Cell growth and death;Cardiovascular disease;Endocrine system;Endocrine system;Development and regeneration;Nervous system;Signal transduction;Immune system;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Drug resistance: antineoplastic;Immune system;Cancer: overview;Immune system;Endocrine system;Cancer: specific types;Signal transduction;Infectious disease: bacterial;Transport and catabolism;Cancer: specific types;Infectious disease: bacterial;Substance dependence;Immune disease;Substance dependence	ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04530//Tight junction;ko04310//Wnt signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05162//Measles;ko05140//Leishmaniasis;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko05133//Pertussis;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05031//Amphetamine addiction;ko05321//Inflammatory bowel disease;ko05030//Cocaine addiction	K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448;K04448	GO:0000228//nuclear chromosome;GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005886//plasma membrane;GO:0017053//transcription repressor complex;GO:0035976//transcription factor AP-1 complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0035497//cAMP response element binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412//R-SMAD binding;GO:0140296//general transcription initiation factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001774//microglial cell activation;GO:0001889//liver development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0003151//outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010634//positive regulation of epithelial cell migration;GO:0030224//monocyte differentiation;GO:0031103//axon regeneration;GO:0031953//negative regulation of protein autophosphorylation;GO:0034614//cellular response to reactive oxygen species;GO:0035026//leading edge cell differentiation;GO:0035994//response to muscle stretch;GO:0042127//regulation of cell population proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0043922//negative regulation by host of viral transcription;GO:0043923//positive regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048146//positive regulation of fibroblast proliferation;GO:0050790//regulation of catalytic activity;GO:0051726//regulation of cell cycle;GO:0060395//SMAD protein signal transduction;GO:0061029//eyelid development in camera-type eye;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071276//cellular response to cadmium ion;GO:0071277//cellular response to calcium ion;GO:0072740//cellular response to anisomycin;GO:0140467//integrated stress response signaling;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:2000144//positive regulation of DNA-templated transcription, initiation"	TF_bZIP
ENSG00000177613	9.29	9.885	11.562	9.644	10.469	9.109	792	847	728	609	754	565	CSTF2T	cleavage stimulation factor subunit 2 tau variant [Source:HGNC Symbol;Acc:HGNC:17086]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14407	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0031124//mRNA 3'-end processing;GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000177614	1.745	2.478	2.152	2.512	1.703	2.968	170	188	117	156	167	145	PGBD5	piggyBac transposable element derived 5 [Source:HGNC Symbol;Acc:HGNC:19405]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004803//transposase activity;GO:0016787//hydrolase activity	"GO:0032196//transposition;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0098038//non-replicative transposition, DNA-mediated"	--
ENSG00000177627	0	0	0	0	0	0	0	0	0	0	0	0	C12orf54	chromosome 12 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:28553]	-	-	-	-	-	-	-	--
ENSG00000177628	48.557	56.762	51.299	56.263	55.198	56.342	2297	2697	1789	1976	2199	1937	GBA	glucosylceramidase beta [Source:HGNC Symbol;Acc:HGNC:4177]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K01201;K01201;K01201;K01201	GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	"GO:0004348//glucosylceramidase activity;GO:0005102//signaling receptor binding;GO:0005124//scavenger receptor binding;GO:0005515//protein binding;GO:0008422//beta-glucosidase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046527//glucosyltransferase activity;GO:0050295//steryl-beta-glucosidase activity"	GO:0000423//mitophagy;GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006678//glucosylceramide metabolic process;GO:0006680//glucosylceramide catabolic process;GO:0006914//autophagy;GO:0007005//mitochondrion organization;GO:0007040//lysosome organization;GO:0007417//central nervous system development;GO:0008152//metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008340//determination of adult lifespan;GO:0009267//cellular response to starvation;GO:0009268//response to pH;GO:0014004//microglia differentiation;GO:0016241//regulation of macroautophagy;GO:0019882//antigen processing and presentation;GO:0019915//lipid storage;GO:0021694//cerebellar Purkinje cell layer formation;GO:0021859//pyramidal neuron differentiation;GO:0022904//respiratory electron transport chain;GO:0023021//termination of signal transduction;GO:0030259//lipid glycosylation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032006//regulation of TOR signaling;GO:0032268//regulation of cellular protein metabolic process;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032715//negative regulation of interleukin-6 production;GO:0033077//T cell differentiation in thymus;GO:0033561//regulation of water loss via skin;GO:0033574//response to testosterone;GO:0035307//positive regulation of protein dephosphorylation;GO:0042391//regulation of membrane potential;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043243//positive regulation of protein-containing complex disassembly;GO:0043407//negative regulation of MAP kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043589//skin morphogenesis;GO:0043627//response to estrogen;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0048469//cell maturation;GO:0048854//brain morphogenesis;GO:0048872//homeostasis of number of cells;GO:0050728//negative regulation of inflammatory response;GO:0050877//nervous system process;GO:0050905//neuromuscular process;GO:0051246//regulation of protein metabolic process;GO:0051247//positive regulation of protein metabolic process;GO:0051402//neuron apoptotic process;GO:0061518//microglial cell proliferation;GO:0061744//motor behavior;GO:0071356//cellular response to tumor necrosis factor;GO:0071425//hematopoietic stem cell proliferation;GO:0071548//response to dexamethasone;GO:0072676//lymphocyte migration;GO:0097066//response to thyroid hormone;GO:1901215//negative regulation of neuron death;GO:1901805//beta-glucoside catabolic process;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process;GO:1903061//positive regulation of protein lipidation;GO:1904457//positive regulation of neuronal action potential;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization;GO:1905037//autophagosome organization;GO:1905165//regulation of lysosomal protein catabolic process	--
ENSG00000177646	18.359	21.407	17.789	16.796	19.695	19.84	863	942	680	634	765	608	ACAD9	acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0031966//mitochondrial membrane	"GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0051791//medium-chain fatty acid metabolic process	--
ENSG00000177663	5.376	6.24	5.786	4.361	6.277	6.027	472	524	405	387	504	440	IL17RA	interleukin 17 receptor A [Source:HGNC Symbol;Acc:HGNC:5985]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Endocrine and metabolic disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04936//Alcoholic liver disease;ko04657//IL-17 signaling pathway	K05164;K05164;K05164	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030368//interleukin-17 receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0009615//response to virus;GO:0030163//protein catabolic process;GO:0032736//positive regulation of interleukin-13 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032754//positive regulation of interleukin-5 production;GO:0032755//positive regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0050832//defense response to fungus;GO:0071621//granulocyte chemotaxis;GO:0072537//fibroblast activation;GO:0072538//T-helper 17 type immune response;GO:0097400//interleukin-17-mediated signaling pathway;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production	--
ENSG00000177666	10.536	11.932	12.321	11.476	14.313	11.985	528	601	456	426	606	437	PNPLA2	patatin like phospholipase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30802]	Metabolism;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Environmental adaptation;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00561//Glycerolipid metabolism;ko04923//Regulation of lipolysis in adipocytes	K16816;K16816;K16816;K16816	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004465//lipoprotein lipase activity;GO:0004806//triglyceride lipase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016787//hydrolase activity;GO:0050253//retinyl-palmitate esterase activity	GO:0006629//lipid metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0010891//negative regulation of sequestering of triglyceride;GO:0010898//positive regulation of triglyceride catabolic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0019915//lipid storage;GO:0034389//lipid droplet organization;GO:0036155//acylglycerol acyl-chain remodeling;GO:0042572//retinol metabolic process;GO:0044242//cellular lipid catabolic process;GO:0055088//lipid homeostasis	--
ENSG00000177669	0.059	0	0.04	0.079	0.104	0.04	2	0	1	2	3	1	MBOAT4	membrane bound O-acyltransferase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:32311]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0008374//O-acyltransferase activity;GO:0016412//serine O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups"	GO:0016486//peptide hormone processing;GO:0018190//protein octanoylation;GO:0018191//peptidyl-serine octanoylation;GO:0030258//lipid modification;GO:0043543//protein acylation;GO:0051366//protein decanoylation	--
ENSG00000177673	0	0	0	0	0	0	0	0	0	0	0	0	TEX44	testis expressed 44 [Source:HGNC Symbol;Acc:HGNC:28563]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000177674	29.383	30.615	30.815	34.636	31.8	32.509	676	702	521	583	618	545	AGTRAP	angiotensin II receptor associated protein [Source:HGNC Symbol;Acc:HGNC:13539]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0001666//response to hypoxia;GO:0008217//regulation of blood pressure;GO:0038166//angiotensin-activated signaling pathway	--
ENSG00000177675	0	0	0	0	0.025	0	0	0	0	0	2	0	CD163L1	CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005044//scavenger receptor activity	GO:0006897//endocytosis	--
ENSG00000177679	0.084	0.027	0.054	0.054	0.047	0.055	6	2	3	3	3	3	SRRM3	serine/arginine repetitive matrix 3 [Source:HGNC Symbol;Acc:HGNC:26729]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000177683	7.367	6.694	5.899	5.64	7.171	7.163	473	398	256	227	301	287	THAP5	THAP domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23188]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0002020//protease binding;GO:0003677//DNA binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0045786//negative regulation of cell cycle	THAP
ENSG00000177684	0	0	0	0	0	0	0	0	0	0	0	0	DEFB114	defensin beta 114 [Source:HGNC Symbol;Acc:HGNC:18095]	-	-	-	-	GO:0005576//extracellular region	GO:0001530//lipopolysaccharide binding	GO:0006952//defense response;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0042742//defense response to bacterium;GO:0043407//negative regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061760//antifungal innate immune response	--
ENSG00000177685	0.704	0.866	1.057	0.421	1.115	1.051	27	39	24	14	36	24	CRACR2B	calcium release activated channel regulator 2B [Source:HGNC Symbol;Acc:HGNC:28703]	-	-	-	-	GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0002115//store-operated calcium entry;GO:0034613//cellular protein localization;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000177688	0	0	0	0	0	0	0	0	0	0	0	0	SUMO4	small ubiquitin like modifier 4 [Source:HGNC Symbol;Acc:HGNC:21181]	Human Diseases;Genetic Information Processing	Cardiovascular disease;Translation	ko05418//Fluid shear stress and atherosclerosis;ko03013//Nucleocytoplasmic transport	K12160;K12160	GO:0005634//nucleus;GO:0106068//SUMO ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0031386//protein tag;GO:0044389//ubiquitin-like protein ligase binding	"GO:0016925//protein sumoylation;GO:0034599//cellular response to oxidative stress;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043388//positive regulation of DNA binding;GO:0043392//negative regulation of DNA binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:1900180//regulation of protein localization to nucleus"	--
ENSG00000177689	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB10	MAGE family member B10 [Source:HGNC Symbol;Acc:HGNC:25377]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000177692	0.782	1.015	0.817	0.996	0.661	0.757	28	36	21	26	19	18	DNAJC28	DnaJ heat shock protein family (Hsp40) member C28 [Source:HGNC Symbol;Acc:HGNC:1297]	-	-	-	-	GO:0017119//Golgi transport complex	GO:0005515//protein binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030//Golgi organization;GO:0048213//Golgi vesicle prefusion complex stabilization"	--
ENSG00000177693	0	0	0	0	0	0	0	0	0	0	0	0	OR4F4	olfactory receptor family 4 subfamily F member 4 [Source:HGNC Symbol;Acc:HGNC:8301]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000177694	1.53	0.533	0.9	0.64	1.128	1.318	180	109	66	62	85	63	NAALADL2	N-acetylated alpha-linked acidic dipeptidase like 2 [Source:HGNC Symbol;Acc:HGNC:23219]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0009617//response to bacterium	--
ENSG00000177697	107.834	108.048	111.376	110.237	98.145	100.077	3362	3380	2566	2543	2585	2255	CD151	CD151 molecule (Raph blood group) [Source:HGNC Symbol;Acc:HGNC:1630]	-	-	-	-	GO:0005604//basement membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005178//integrin binding;GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0042098//T cell proliferation;GO:0044319//wound healing, spreading of cells;GO:0045807//positive regulation of endocytosis"	--
ENSG00000177700	27.353	25.296	30.999	35.536	29.314	33.206	497	462	416	470	450	439	POLR2L	"RNA polymerase II, I and III subunit L [Source:HGNC Symbol;Acc:HGNC:9199]"	Human Diseases;Organismal Systems;Genetic Information Processing	Neurodegenerative disease;Immune system;Transcription	ko05016//Huntington disease;ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03007;K03007;K03007	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//RNA polymerase II, core complex;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006356//regulation of transcription by RNA polymerase I;GO:0006360//transcription by RNA polymerase I;GO:0006366//transcription by RNA polymerase II;GO:0042797//tRNA transcription by RNA polymerase III"	--
ENSG00000177706	11.628	12.293	11.489	11.353	11.607	11.078	766	814	559	554	646	531	FAM20C	FAM20C golgi associated secretory pathway kinase [Source:HGNC Symbol;Acc:HGNC:22140]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity"	GO:0001501//skeletal system development;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0036179//osteoclast maturation;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0051174//regulation of phosphorus metabolic process;GO:0070166//enamel mineralization;GO:0071895//odontoblast differentiation;GO:0097187//dentinogenesis	--
ENSG00000177707	24.368	21.946	22.429	18.441	17.309	18.123	1154	909	773	537	684	659	NECTIN3	nectin cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17664]	Environmental Information Processing;Cellular Processes	Signaling molecules and interaction;Cellular community - eukaryotes	ko04514//Cell adhesion molecules;ko04520//Adherens junction	K06592;K06592	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043296//apical junction complex;GO:0044291//cell-cell contact zone;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0002089//lens morphogenesis in camera-type eye;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007286//spermatid development;GO:0009566//fertilization;GO:0060042//retina morphogenesis in camera-type eye;GO:0061951//establishment of protein localization to plasma membrane;GO:0098609//cell-cell adhesion;GO:1902414//protein localization to cell junction	--
ENSG00000177710	0	0	0	0.048	0	0	0	0	0	1	0	0	SLC35G5	solute carrier family 35 member G5 [Source:HGNC Symbol;Acc:HGNC:15546]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000177721	0	0.051	0.275	0.058	0.135	0	0	1	4	2	3	0	ANXA2R	annexin A2 receptor [Source:HGNC Symbol;Acc:HGNC:33463]	-	-	-	-	-	GO:0005515//protein binding;GO:0038023//signaling receptor activity	-	--
ENSG00000177728	28.888	29.989	33.75	37.231	42.529	32.453	1803	2024	1514	1746	2146	1584.67	TMEM94	transmembrane protein 94 [Source:HGNC Symbol;Acc:HGNC:28983]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000177731	37.597	40.361	41.099	42.672	43.733	40.901	3193	3272	2421	2489	3059	2295	FLII	FLII actin remodeling protein [Source:HGNC Symbol;Acc:HGNC:3750]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0034451//centriolar satellite	"GO:0003779//actin binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0051015//actin filament binding"	GO:0008154//actin polymerization or depolymerization;GO:0030036//actin cytoskeleton organization;GO:0030239//myofibril assembly;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping	--
ENSG00000177732	14.712	14.442	17.587	19.43	17.023	16.491	1426	1407	1259	1395	1394	1163	SOX12	SRY-box transcription factor 12 [Source:HGNC Symbol;Acc:HGNC:11198]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032993//protein-DNA complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0021510//spinal cord development;GO:0030154//cell differentiation;GO:0045165//cell fate commitment;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	HMG
ENSG00000177733	16.19	15.469	16.422	16.8	16.537	16.723	2926	2810	2192	2249	2525	2199	HNRNPA0	heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0019901//protein kinase binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	GO:0006397//mRNA processing;GO:0006954//inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000177752	0.4	0.849	0.704	0.388	0.26	0.377	3	8	7	6	5	6	YIPF7	Yip1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:26825]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048280//vesicle fusion with Golgi apparatus	--
ENSG00000177791	1.113	1.439	1.456	0.801	0.702	0.968	30	39	29	16	16	19	MYOZ1	myozenin 1 [Source:HGNC Symbol;Acc:HGNC:13752]	-	-	-	-	GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0031143//pseudopodium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding;GO:0031433//telethonin binding;GO:0051373//FATZ binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0030239//myofibril assembly;GO:0042060//wound healing;GO:0043086//negative regulation of catalytic activity;GO:0043417//negative regulation of skeletal muscle tissue regeneration;GO:0043503//skeletal muscle fiber adaptation;GO:0045214//sarcomere organization;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade	--
ENSG00000177807	0.012	0	0	0	0.029	0	1	0	0	0	2	0	KCNJ10	potassium inwardly rectifying channel subfamily J member 10 [Source:HGNC Symbol;Acc:HGNC:6256]	Human Diseases;Organismal Systems	Neurodegenerative disease;Digestive system	ko05016//Huntington disease;ko04971//Gastric acid secretion	K05003;K05003	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0044297//cell body;GO:0097449//astrocyte projection;GO:0097546//ciliary base;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015272//ATP-activated inward rectifier potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007601//visual perception;GO:0007628//adult walking behavior;GO:0014003//oligodendrocyte development;GO:0022010//central nervous system myelination;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0051935//glutamate reuptake;GO:0055075//potassium ion homeostasis;GO:0060075//regulation of resting membrane potential;GO:0071805//potassium ion transmembrane transport;GO:1905515//non-motile cilium assembly;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000177830	76.778	87.383	79.206	91.891	87.528	75.959	2337	2612	1796	2066	2267	1696	CHID1	chitinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28474]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008061//chitin binding;GO:0070492//oligosaccharide binding	GO:0002376//immune system process;GO:0005975//carbohydrate metabolic process;GO:0045087//innate immune response;GO:1900016//negative regulation of cytokine production involved in inflammatory response	--
ENSG00000177839	1.194	0.454	0.284	0.519	0.415	0.424	44.18	41.51	19.06	34.95	30.44	28.05	PCDHB9	protocadherin beta 9 [Source:HGNC Symbol;Acc:HGNC:8694]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000177842	2.838	1.871	2.299	1.433	1.304	1.117	111	97	73	66	65	41	ZNF620	zinc finger protein 620 [Source:HGNC Symbol;Acc:HGNC:28742]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000177853	2.201	1.35	1.356	1.172	1.404	1.634	374	230	170	145	203	204	ZNF518A	zinc finger protein 518A [Source:HGNC Symbol;Acc:HGNC:29009]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000177854	6.568	4.559	5.894	5.2	7.182	6.101	164	138	108	116	132	127	TMEM187	transmembrane protein 187 [Source:HGNC Symbol;Acc:HGNC:13705]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000177868	8.907	6.675	8.345	6.463	4.918	8.457	146	111	102	79	69	103	SVBP	small vasohibin binding protein [Source:HGNC Symbol;Acc:HGNC:29204]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0045177//apical part of cell	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0006508//proteolysis;GO:0009306//protein secretion;GO:0010596//negative regulation of endothelial cell migration;GO:0031397//negative regulation of protein ubiquitination;GO:0061564//axon development;GO:1905048//regulation of metallopeptidase activity	--
ENSG00000177873	2.901	2.889	2.898	3.122	3.151	3.228	255	267	176	185	211	208	ZNF619	zinc finger protein 619 [Source:HGNC Symbol;Acc:HGNC:26910]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000177875	0.296	0.462	0.372	0.314	0.35	0.522	14	22	13	11	14	18	CCDC184	coiled-coil domain containing 184 [Source:HGNC Symbol;Acc:HGNC:33749]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000177879	21.99	23.907	22.919	22.75	20.438	27.055	582	636	448	446	457	521	AP3S1	adaptor related protein complex 3 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:2013]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12399	GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030119//AP-type membrane coat adaptor complex;GO:0030123//AP-3 adaptor complex;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:1904115//axon cytoplasm	GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006896//Golgi to vacuole transport;GO:0008089//anterograde axonal transport;GO:0008286//insulin receptor signaling pathway;GO:0015031//protein transport;GO:0016183//synaptic vesicle coating;GO:0016192//vesicle-mediated transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0036465//synaptic vesicle recycling;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly"	--
ENSG00000177885	30.485	27.83	29.54	31.328	30.588	32.849	1800	1688	1274	1402	1492	1434	GRB2	growth factor receptor bound protein 2 [Source:HGNC Symbol;Acc:HGNC:4566]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Substance dependence;Immune system;Cancer: overview;Signal transduction;Cancer: specific types;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Nervous system;Endocrine system;Immune system;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04660//T cell receptor signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05223//Non-small cell lung cancer;ko05221//Acute myeloid leukemia;ko05213//Endometrial cancer"	K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364;K04364	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0008180//COP9 signalosome;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0070436//Grb2-EGFR complex	GO:0001784//phosphotyrosine residue binding;GO:0003723//RNA binding;GO:0005154//epidermal growth factor receptor binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0043560//insulin receptor substrate binding;GO:0044877//protein-containing complex binding;GO:0046875//ephrin receptor binding;GO:0051219//phosphoprotein binding	GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007568//aging;GO:0008286//insulin receptor signaling pathway;GO:0030154//cell differentiation;GO:0030838//positive regulation of actin filament polymerization;GO:0031532//actin cytoskeleton reorganization;GO:0031623//receptor internalization;GO:0042770//signal transduction in response to DNA damage;GO:0043408//regulation of MAPK cascade;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0071479//cellular response to ionizing radiation;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000177888	4.915	2.601	2.683	2.613	2.182	3.084	852	466	328	324	297	400	ZBTB41	zinc finger and BTB domain containing 41 [Source:HGNC Symbol;Acc:HGNC:24819]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000177889	35.023	33.623	32.273	33.849	30.293	29.694	1330.23	1303.43	1019.35	919.59	944.34	918.26	UBE2N	ubiquitin conjugating enzyme E2 N [Source:HGNC Symbol;Acc:HGNC:12492]	Human Diseases;Genetic Information Processing	"Infectious disease: bacterial;Folding, sorting and degradation"	ko05131//Shigellosis;ko04120//Ubiquitin mediated proteolysis	K10580;K10580	GO:0000151//ubiquitin ligase complex;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031372//UBC13-MMS2 complex;GO:0032991//protein-containing complex;GO:0035370//UBC13-UEV1A complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0000724//double-strand break repair via homologous recombination;GO:0000729//DNA double-strand break processing;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006301//postreplication repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0031058//positive regulation of histone modification;GO:0032446//protein modification by small protein conjugation;GO:0033182//regulation of histone ubiquitination;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045739//positive regulation of DNA repair;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0070534//protein K63-linked ubiquitination;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1902533//positive regulation of intracellular signal transduction;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000177910	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31C2	SPATA31 subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:24508]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000177917	8.216	6.601	7.23	6.03	6.449	8.015	259.1	214.22	159	140	165.22	176.15	ARL6IP6	ADP ribosylation factor like GTPase 6 interacting protein 6 [Source:HGNC Symbol;Acc:HGNC:24048]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000177932	1.685	0.903	1.218	0.928	1.026	1.158	206	111	110	84	106	103	ZNF354C	zinc finger protein 354C [Source:HGNC Symbol;Acc:HGNC:16736]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000177938	0	0	0	0	0	0	0	0	0	0	0	0	CAPZA3	capping actin protein of muscle Z-line subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:24205]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K10364	GO:0005634//nucleus;GO:0005829//cytosol;GO:0008290//F-actin capping protein complex;GO:0016020//membrane;GO:0030863//cortical cytoskeleton	GO:0003779//actin binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping	--
ENSG00000177943	0.606	0.848	0.987	0.785	1.121	0.986	46	67	57	47	73	54	MAMDC4	MAM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24083]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0015031//protein transport	--
ENSG00000177947	0	0	0	0	0	0	0	0	0	0	0	0	ODF3	outer dense fiber of sperm tails 3 [Source:HGNC Symbol;Acc:HGNC:19905]	-	-	-	-	GO:0001520//outer dense fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000177951	21.273	24.67	23.544	25.125	25.199	23.54	1215	1407	973	1023	1186	960	BET1L	Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08504	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031201//SNARE complex;GO:0098791//Golgi apparatus subcompartment	GO:0005484//SNAP receptor activity	"GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0061025//membrane fusion;GO:2000156//regulation of retrograde vesicle-mediated transport, Golgi to ER"	--
ENSG00000177954	377.525	373.87	367.391	389.269	270.297	321.631	2761	2747	1985	2108	1671	1711	RPS27	ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:10416]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02978;K02978	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0014069//postsynaptic density;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000028//ribosomal small subunit assembly;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation	--
ENSG00000177963	32.144	37.669	35.943	38.016	34.609	32.072	1920	2178	1393	1366	1545	1357	RIC8A	RIC8 guanine nucleotide exchange factor A [Source:HGNC Symbol;Acc:HGNC:29550]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0001965//G-protein alpha-subunit binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001944//vasculature development;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007369//gastrulation;GO:0008542//visual learning;GO:0009416//response to light stimulus;GO:0042074//cell migration involved in gastrulation;GO:0050790//regulation of catalytic activity;GO:0070586//cell-cell adhesion involved in gastrulation;GO:0071711//basement membrane organization	--
ENSG00000177971	24.029	19.518	21.747	26.4	24.904	23.108	594.19	477.51	398.67	490.34	503.61	421.32	IMP3	IMP U3 small nucleolar ribonucleoprotein 3 [Source:HGNC Symbol;Acc:HGNC:14497]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14560	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030684//preribosome;GO:0032040//small-subunit processome;GO:0034457//Mpp10 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0030515//snoRNA binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000177981	11.13	12.164	10.509	11.402	11.318	11.934	545	565	391	407	475	426	ASB8	ankyrin repeat and SOCS box containing 8 [Source:HGNC Symbol;Acc:HGNC:17183]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000177984	0	0	0	0	0	0	0	0	0	0	0	0	LCN15	lipocalin 15 [Source:HGNC Symbol;Acc:HGNC:33777]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0036094//small molecule binding	-	--
ENSG00000177989	0.184	0.183	0.15	0.083	0.429	0.076	3	3	2	1	4	1	ODF3B	outer dense fiber of sperm tails 3B [Source:HGNC Symbol;Acc:HGNC:34388]	-	-	-	-	GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000177990	0.17	0.236	0.099	0.261	0.373	0.477	14	11	6	13	26	13	DPY19L2	dpy-19 like 2 [Source:HGNC Symbol;Acc:HGNC:19414]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan;GO:0030154//cell differentiation	--
ENSG00000177992	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31E1	SPATA31 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:26672]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000177994	0.14	0.314	0.095	0	0.138	0.048	4	9	2	0	2	1	C2orf73	chromosome 2 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:26861]	-	-	-	-	-	-	-	--
ENSG00000178015	0	0	0	0	0	0	0	0	0	0	0	0	GPR150	G protein-coupled receptor 150 [Source:HGNC Symbol;Acc:HGNC:23628]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000178021	0	0	0	0	0	0	0	0	0	0	0	0	TSPYL6	TSPY like 6 [Source:HGNC Symbol;Acc:HGNC:14521]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly	--
ENSG00000178026	6.634	7.702	7.48	4.332	6.363	4.594	196	217	164	92	156	97	LRRC75B	leucine rich repeat containing 75B [Source:HGNC Symbol;Acc:HGNC:33155]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000178028	20.229	20.282	20.945	22.693	22.003	19.131	639	631	479	500	555	390	DMAP1	DNA methyltransferase 1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18291]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043229//intracellular organelle	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0040008//regulation of growth;GO:0042307//positive regulation of protein import into nucleus;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045471//response to ethanol;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000178031	0.864	1.005	0.652	0.996	0.594	0.593	104	126	64	69	66	51	ADAMTSL1	ADAMTS like 1 [Source:HGNC Symbol;Acc:HGNC:14632]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane	GO:0004222//metalloendopeptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0030198//extracellular matrix organization	--
ENSG00000178033	0.153	0.191	0.093	0.013	0.006	0.014	31	39	14	2	1	2	CALHM5	calcium homeostasis modulator family member 5 [Source:HGNC Symbol;Acc:HGNC:21568]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005261//cation channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000178035	63.91	68.119	62.773	61.144	55.59	53.718	2198	2352	1592	1556	1616	1344	IMPDH2	inosine monophosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:6053]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes	K00088;K00088;K00088	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0003938//IMP dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006183//GTP biosynthetic process;GO:0007623//circadian rhythm;GO:0046651//lymphocyte proliferation;GO:0060041//retina development in camera-type eye;GO:0071353//cellular response to interleukin-4;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000178038	0.219	0.168	0.171	0.156	0.194	0.236	22	14	10	11	16	17	ALS2CL	ALS2 C-terminal like [Source:HGNC Symbol;Acc:HGNC:20605]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007032//endosome organization;GO:0050790//regulation of catalytic activity	--
ENSG00000178053	10.917	12.058	8.278	5.289	7.259	8.457	321	327	176	100	166	156	MLF1	myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15622	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding	"GO:0002318//myeloid progenitor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0030154//cell differentiation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902806//regulation of cell cycle G1/S phase transition"	--
ENSG00000178057	43.384	46.019	44.001	51.73	50.813	52.432	809	865	608	715	802	713	NDUFAF3	NADH:ubiquinone oxidoreductase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:29918]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K09008	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	GO:0005515//protein binding	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000178074	7.289	5.25	5.889	5.308	5.318	6.894	558	404	333	301	344	384	C2orf69	chromosome 2 open reading frame 69 [Source:HGNC Symbol;Acc:HGNC:26799]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0070469//respirasome	-	GO:0006119//oxidative phosphorylation	--
ENSG00000178075	0.776	0.62	0.557	0.307	0.63	0.366	49	42	23	17	42	21	GRAMD1C	GRAM domain containing 1C [Source:HGNC Symbol;Acc:HGNC:25252]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding;GO:0032934//sterol binding;GO:0120015//sterol transfer activity;GO:0120020//cholesterol transfer activity	GO:0006869//lipid transport;GO:0032366//intracellular sterol transport;GO:0071397//cellular response to cholesterol;GO:0120009//intermembrane lipid transfer	--
ENSG00000178078	13.261	15.115	13.866	14.914	12.372	14.503	391	447	300	323	314	304	STAP2	signal transducing adaptor family member 2 [Source:HGNC Symbol;Acc:HGNC:30430]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0035591//signaling adaptor activity	-	--
ENSG00000178084	0	0	0	0	0	0	0	0	0	0	0	0	HTR3C	5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003]	Organismal Systems;Organismal Systems	Nervous system;Sensory system	ko04726//Serotonergic synapse;ko04742//Taste transduction	K04819;K04819	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:1904602//serotonin-activated cation-selective channel complex	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0022850//serotonin-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000178093	0.616	1.127	1.374	1.628	0.822	1.574	17	27	28	26	16	29	TSSK6	testis specific serine kinase 6 [Source:HGNC Symbol;Acc:HGNC:30410]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0035092//sperm chromatin condensation;GO:0035556//intracellular signal transduction	--
ENSG00000178096	6.956	5.714	5.348	3.904	5.613	5.387	128	106	73	53	87	72	BOLA1	bolA family member 1 [Source:HGNC Symbol;Acc:HGNC:24263]	-	-	-	-	GO:0005739//mitochondrion;GO:1990229//iron-sulfur cluster assembly complex	GO:0005515//protein binding	GO:0016226//iron-sulfur cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000178104	30.385	29.01	26.671	26.076	22.34	25.932	3226	2873	2064	1729	1953	1950	PDE4DIP	phosphodiesterase 4D interacting protein [Source:HGNC Symbol;Acc:HGNC:15580]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0030016//myofibril;GO:1903754//cortical microtubule plus-end	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0060090//molecular adaptor activity	GO:0030953//astral microtubule organization;GO:0034622//cellular protein-containing complex assembly;GO:0090063//positive regulation of microtubule nucleation;GO:1903358//regulation of Golgi organization	--
ENSG00000178105	5.29	4.935	4.851	2.731	3.667	4.132	353	331	240	135	209	201	DDX10	DEAD-box helicase 10 [Source:HGNC Symbol;Acc:HGNC:2735]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006364//rRNA processing;GO:0097065//anterior head development	--
ENSG00000178115	0	0.053	0.055	0.13	0	0.092	0	5.66	4.33	10.23	0	7.09	GOLGA8Q	golgin A8 family member Q [Source:HGNC Symbol;Acc:HGNC:44408]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000178125	0.267	0.044	0	0.12	0.053	0.061	6	1	0	2	1	1	PPP1R42	protein phosphatase 1 regulatory subunit 42 [Source:HGNC Symbol;Acc:HGNC:33732]	-	-	-	-	GO:0002177//manchette;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0070840//dynein complex binding	GO:0010921//regulation of phosphatase activity	--
ENSG00000178127	43.879	45.893	44.634	45.567	40.751	44.071	780	820	586	600	612	570	NDUFV2	NADH:ubiquinone oxidoreductase core subunit V2 [Source:HGNC Symbol;Acc:HGNC:7717]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943;K03943	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0070469//respirasome	"GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007399//nervous system development;GO:0009060//aerobic respiration;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0048738//cardiac muscle tissue development"	--
ENSG00000178149	14.396	14.258	15.155	14.265	10.877	14.002	457.71	450.47	367.84	345.45	326.2	358	DALRD3	DALR anticodon binding domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25536]	-	-	-	-	-	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004814//arginine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0006418//tRNA aminoacylation for protein translation;GO:0006420//arginyl-tRNA aminoacylation;GO:0106217//tRNA C3-cytosine methylation	--
ENSG00000178150	0.111	0.189	0.15	0.037	0.033	0.038	4	4	4	1	1	1	ZNF114	zinc finger protein 114 [Source:HGNC Symbol;Acc:HGNC:12894]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000178163	6.106	4.861	5.787	3.21	3.898	5.357	817	662	448	343	475	423	ZNF518B	zinc finger protein 518B [Source:HGNC Symbol;Acc:HGNC:29365]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000178171	0	0	0	0	0	0	0	0	0	0	0	0	AMER3	APC membrane recruitment protein 3 [Source:HGNC Symbol;Acc:HGNC:26771]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008013//beta-catenin binding;GO:0008289//lipid binding"	GO:0016055//Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway	--
ENSG00000178172	0	0	0	0	0	0	0	0	0	0	0	0	SPINK6	serine peptidase inhibitor Kazal type 6 [Source:HGNC Symbol;Acc:HGNC:29486]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0007417//central nervous system development;GO:0010466//negative regulation of peptidase activity;GO:0030154//cell differentiation;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:1902572//negative regulation of serine-type peptidase activity	--
ENSG00000178175	0	0	0.021	0	0	0	0	0	2	0	0	0	ZNF366	zinc finger protein 366 [Source:HGNC Symbol;Acc:HGNC:18316]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0043627//response to estrogen	zf-C2H2
ENSG00000178177	2.626	1.728	2.918	2.213	1.838	2.432	275.93	181.34	171.96	136.91	150.98	190.2	LCORL	ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990226//histone methyltransferase binding	GO:0006357//regulation of transcription by RNA polymerase II	HTH
ENSG00000178184	2.279	1.851	2.573	2.317	1.745	1.33	157	148	106	101	105	77	PARD6G	par-6 family cell polarity regulator gamma [Source:HGNC Symbol;Acc:HGNC:16076]	Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Infectious disease: viral;Transport and catabolism;Signal transduction;Development and regeneration;Cellular community - eukaryotes;Signal transduction;Signal transduction	ko05165//Human papillomavirus infection;ko04144//Endocytosis;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04391//Hippo signaling pathway - fly	K06093;K06093;K06093;K06093;K06093;K06093;K06093	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0070160//tight junction;GO:0120157//PAR polarity complex	GO:0005080//protein kinase C binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0051301//cell division;GO:0060341//regulation of cellular localization	--
ENSG00000178187	0.083	0.101	0.11	0.14	0.049	0.114	4	5	4	5	2	4	ZNF454	zinc finger protein 454 [Source:HGNC Symbol;Acc:HGNC:21200]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178188	18.248	19.148	17.368	17.714	18.702	19.235	772	767	628	641	773	674	SH2B1	SH2B adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:30417]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12459	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding;GO:0035591//signaling adaptor activity	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030032//lamellipodium assembly;GO:0035556//intracellular signal transduction;GO:0045840//positive regulation of mitotic nuclear division;GO:0060391//positive regulation of SMAD protein signal transduction;GO:2000278//regulation of DNA biosynthetic process	--
ENSG00000178199	0.059	0.008	0.011	0.034	0.07	0.012	7	1	1	3	7	1	ZC3H12D	zinc finger CCCH-type containing 12D [Source:HGNC Symbol;Acc:HGNC:21175]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006402//mRNA catabolic process;GO:0030308//negative regulation of cell growth;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000178201	0.144	0.122	0.167	0.083	0.097	0.141	7	6	6	3	4	5	VN1R1	vomeronasal 1 receptor 1 [Source:HGNC Symbol;Acc:HGNC:13548]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0016503//pheromone receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008150//biological_process;GO:0019236//response to pheromone	--
ENSG00000178202	14.983	13.446	11.655	7.416	7.616	8.849	1316	1171	758	468	552	568	POGLUT3	protein O-glucosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:28496]	-	-	-	-	GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0012505//endomembrane system	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity;GO:0035252//UDP-xylosyltransferase activity;GO:0046527//glucosyltransferase activity;GO:0140561//EGF-domain serine glucosyltransferase activity;GO:0140562//EGF-domain serine xylosyltransferase activity	GO:0006486//protein glycosylation;GO:0018242//protein O-linked glycosylation via serine	--
ENSG00000178209	48.069	50.11	50.754	53.445	55.649	44.024	12885	13490.95	10058	10659	12636	8701	PLEC	plectin [Source:HGNC Symbol;Acc:HGNC:9069]	-	-	-	-	GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016528//sarcoplasm;GO:0030016//myofibril;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0030424//axon;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0043209//myelin sheath;GO:0043292//contractile fiber;GO:0045111//intermediate filament cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0002162//dystroglycan binding;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle;GO:0030506//ankyrin binding;GO:0043621//protein self-association;GO:0045296//cadherin binding	GO:0000902//cell morphogenesis;GO:0002522//leukocyte migration involved in immune response;GO:0003334//keratinocyte development;GO:0006469//negative regulation of protein kinase activity;GO:0006997//nucleus organization;GO:0007005//mitochondrion organization;GO:0007015//actin filament organization;GO:0007519//skeletal muscle tissue development;GO:0010467//gene expression;GO:0010761//fibroblast migration;GO:0010818//T cell chemotaxis;GO:0014866//skeletal myofibril assembly;GO:0019226//transmission of nerve impulse;GO:0022011//myelination in peripheral nervous system;GO:0022904//respiratory electron transport chain;GO:0030036//actin cytoskeleton organization;GO:0030216//keratinocyte differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0031581//hemidesmosome assembly;GO:0031668//cellular response to extracellular stimulus;GO:0032094//response to food;GO:0032287//peripheral nervous system myelin maintenance;GO:0034332//adherens junction organization;GO:0034613//cellular protein localization;GO:0035264//multicellular organism growth;GO:0042060//wound healing;GO:0043114//regulation of vascular permeability;GO:0043588//skin development;GO:0043933//protein-containing complex subunit organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0045109//intermediate filament organization;GO:0045214//sarcomere organization;GO:0045445//myoblast differentiation;GO:0048741//skeletal muscle fiber development;GO:0048870//cell motility;GO:0055013//cardiac muscle cell development;GO:0061436//establishment of skin barrier;GO:0070584//mitochondrion morphogenesis;GO:0071260//cellular response to mechanical stimulus;GO:0071464//cellular response to hydrostatic pressure;GO:0071498//cellular response to fluid shear stress;GO:0120193//tight junction organization;GO:2000689//actomyosin contractile ring assembly actin filament organization;GO:2000983//regulation of ATP citrate synthase activity	--
ENSG00000178217	0	0	0	0	0.02	0	0	0	0	0	1	0	SH2D4B	SH2 domain containing 4B [Source:HGNC Symbol;Acc:HGNC:31440]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000178222	1.189	1.082	1.036	1.374	1.757	1.674	43	31	20	30	36	32	RNF212	ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005694//chromosome	GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0046872//metal ion binding	GO:0006311//meiotic gene conversion;GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0016925//protein sumoylation;GO:0051026//chiasma assembly;GO:0051321//meiotic cell cycle	--
ENSG00000178226	0	0.091	0.027	0.027	0	0	0	1	1	1	0	0	PRSS36	serine protease 36 [Source:HGNC Symbol;Acc:HGNC:26906]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000178229	1.058	1.196	1.451	0.547	0.944	0.79	81	92	82	31	61.03	44	ZNF543	zinc finger protein 543 [Source:HGNC Symbol;Acc:HGNC:25281]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178233	0.035	0.104	0.11	0.013	0.081	0.067	3.61	10.67	8.28	1	7	5	TMEM151B	transmembrane protein 151B [Source:HGNC Symbol;Acc:HGNC:21315]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000178234	17.307	21.882	20.873	24.102	24.398	19.538	955	1166	825	964	1073	761	GALNT11	polypeptide N-acetylgalactosaminyltransferase 11 [Source:HGNC Symbol;Acc:HGNC:19875]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0007368//determination of left/right symmetry;GO:0008593//regulation of Notch signaling pathway;GO:0016266//O-glycan processing;GO:0018243//protein O-linked glycosylation via threonine;GO:0060271//cilium assembly;GO:0061314//Notch signaling involved in heart development	--
ENSG00000178235	0.01	0.03	0.025	0	0.012	0.013	1	3	2	0	1	1	SLITRK1	SLIT and NTRK like family member 1 [Source:HGNC Symbol;Acc:HGNC:20297]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0030534//adult behavior;GO:0035264//multicellular organism growth;GO:0042592//homeostatic process;GO:0050772//positive regulation of axonogenesis;GO:0051965//positive regulation of synapse assembly;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000178252	54.802	53.45	89.025	58.507	62.252	61.796	4090.29	4214.53	3709.16	3522.55	4078.8	3692	WDR6	WD repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:12758]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0010507//negative regulation of autophagy;GO:0030488//tRNA methylation;GO:0070314//G1 to G0 transition	--
ENSG00000178257	0	0	0	0	0	0	0	0	0	0	0	0	PRM3	protamine 3 [Source:HGNC Symbol;Acc:HGNC:13732]	-	-	-	-	GO:0000786//nucleosome;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0003677//DNA binding	GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:0030261//chromosome condensation;GO:0030317//flagellated sperm motility	--
ENSG00000178279	0	0	0	0	0	0	0	0	0	0	0	0	TNP2	transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0007283//spermatogenesis;GO:0007340//acrosome reaction;GO:0007341//penetration of zona pellucida;GO:0010954//positive regulation of protein processing;GO:0030154//cell differentiation;GO:0035093//spermatogenesis, exchange of chromosomal proteins"	--
ENSG00000178287	0	0	0	0	0	0	0	0	0	0	0	0	SPAG11A	sperm associated antigen 11A [Source:HGNC Symbol;Acc:HGNC:33342]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000178295	2.981	2.375	2.649	1.989	2.236	1.744	611	381	305	202	297	260	GEN1	GEN1 Holliday junction 5' flap endonuclease [Source:HGNC Symbol;Acc:HGNC:26881]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome	GO:0000287//magnesium ion binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0017108//5'-flap endonuclease activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010824//regulation of centrosome duplication;GO:0031297//replication fork processing;GO:0071139//resolution of recombination intermediates;GO:0071140//resolution of mitotic recombination intermediates;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000178297	0	0	0	0	0.017	0	0	0	0	0	1	0	TMPRSS9	transmembrane serine protease 9 [Source:HGNC Symbol;Acc:HGNC:30079]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000178301	3.389	3.869	4.589	3.582	3.638	3.683	129	148	129	101	117	102	AQP11	aquaporin 11 [Source:HGNC Symbol;Acc:HGNC:19940]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015267//channel activity	GO:0001822//kidney development;GO:0006612//protein targeting to membrane;GO:0006833//water transport;GO:0008284//positive regulation of cell population proliferation;GO:0009992//cellular water homeostasis;GO:0015793//glycerol transport;GO:0030104//water homeostasis;GO:0032364//oxygen homeostasis;GO:0033577//protein glycosylation in endoplasmic reticulum;GO:0048388//endosomal lumen acidification;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0072014//proximal tubule development;GO:0080170//hydrogen peroxide transmembrane transport;GO:1903573//negative regulation of response to endoplasmic reticulum stress;GO:1904293//negative regulation of ERAD pathway	--
ENSG00000178307	14.745	12.867	13.151	13.384	13.939	16.254	293	257	193	197	234	235	TMEM11	transmembrane protein 11 [Source:HGNC Symbol;Acc:HGNC:16823]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization	--
ENSG00000178338	1.75	1.139	1.434	1.236	1.179	2.419	95.59	66.36	61.36	53.08	57.75	76	ZNF354B	zinc finger protein 354B [Source:HGNC Symbol;Acc:HGNC:17197]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178342	0	0.026	0.278	0	0	0	0	1	8	0	0	0	KCNG2	potassium voltage-gated channel modifier subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:6249]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0008016//regulation of heart contraction;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000178343	0	0.062	0	0	0	0	0	3	0	0	0	0	SHISA3	shisa family member 3 [Source:HGNC Symbol;Acc:HGNC:25159]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000178358	0	0	0	0	0	0	0	0	0	0	0	0	OR2D3	olfactory receptor family 2 subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:15146]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000178363	0	0	0	0	0.032	0	0	0	0	0	1	0	CALML3	calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000178372	0	0	0	0	0.718	0	0	0	0	0	11	0	CALML5	calmodulin like 5 [Source:HGNC Symbol;Acc:HGNC:18180]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen	GO:0005509//calcium ion binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0008544//epidermis development;GO:0050790//regulation of catalytic activity	--
ENSG00000178381	7.426	8.69	8.264	7.26	6.352	11.031	136	159	112	98	98	146	ZFAND2A	zinc finger AN1-type containing 2A [Source:HGNC Symbol;Acc:HGNC:28073]	-	-	-	-	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045047//protein targeting to ER;GO:0071243//cellular response to arsenic-containing substance	--
ENSG00000178385	3.433	3.356	3.119	2.694	2.855	2.461	696	676	467	401	489	363	PLEKHM3	pleckstrin homology domain containing M3 [Source:HGNC Symbol;Acc:HGNC:34006]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0046872//metal ion binding	GO:0045445//myoblast differentiation	--
ENSG00000178386	2.216	2.029	3.727	1.564	2.384	2.062	103.94	96.29	103.86	54.01	83.8	74.66	ZNF223	zinc finger protein 223 [Source:HGNC Symbol;Acc:HGNC:13016]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000178394	0	0	0	0	0	0	0	0	0	0	0	0	HTR1A	5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse;ko04742//Taste transduction	K04153;K04153;K04153;K04153	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding;GO:0090722//receptor-receptor interaction	"GO:0001662//behavioral fear response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007210//serotonin receptor signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007610//behavior;GO:0008284//positive regulation of cell population proliferation;GO:0014062//regulation of serotonin secretion;GO:0019229//regulation of vasoconstriction;GO:0035640//exploration behavior;GO:0042053//regulation of dopamine metabolic process;GO:0042428//serotonin metabolic process;GO:0046883//regulation of hormone secretion;GO:0050795//regulation of behavior;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000178395	0	0	0	0.032	0	0	0	0	0	1	0	0	CCDC185	coiled-coil domain containing 185 [Source:HGNC Symbol;Acc:HGNC:26654]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000178397	9.773	10.371	9.252	9.466	10.359	8.715	450	480	314.66	322.88	403	292	FAM220A	family with sequence similarity 220 member A [Source:HGNC Symbol;Acc:HGNC:22422]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0097677//STAT family protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006470//protein dephosphorylation	--
ENSG00000178401	3.955	4.257	3.497	3.268	3.039	3.354	295	318	199	179	186	185	DNAJC22	DnaJ heat shock protein family (Hsp40) member C22 [Source:HGNC Symbol;Acc:HGNC:25802]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000178403	0	0	0	0	0	0	0	0	0	0	0	0	NEUROG2	neurogenin 2 [Source:HGNC Symbol;Acc:HGNC:13805]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0051091//positive regulation of DNA-binding transcription factor activity"	bHLH
ENSG00000178404	0.052	0	0.07	0.356	0.092	0	2	0	2	6.01	3	0	CEP295NL	CEP295 N-terminal like [Source:HGNC Symbol;Acc:HGNC:44659]	-	-	-	-	GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005929//cilium;GO:0042995//cell projection	GO:0008017//microtubule binding	GO:0046599//regulation of centriole replication	--
ENSG00000178409	1.002	0.856	1.235	0.959	0.956	0.843	134	115	122	95	108	82	BEND3	BEN domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23040]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0000182//rDNA binding;GO:0003677//DNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000183//rDNA heterochromatin assembly;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0034773//histone H4-K20 trimethylation;GO:0036124//histone H3-K9 trimethylation;GO:0043967//histone H4 acetylation;GO:0051260//protein homooligomerization;GO:0080182//histone H3-K4 trimethylation;GO:0098532//histone H3-K27 trimethylation;GO:1903580//positive regulation of ATP metabolic process	--
ENSG00000178425	17.026	15.718	19.152	15.802	16.583	12.588	948	862	608	605	733	578	NT5DC1	5'-nucleotidase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21556]	-	-	-	-	-	GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000178440	0.474	0.152	0.262	0.732	0.694	0.266	32.51	11.35	11.99	38.48	35.42	14.13	TIMM23B-AGAP6	TIMM23B-AGAP6 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:45009]	Organismal Systems	Aging	ko04212//Longevity regulating pathway - worm	K17794	-	-	-	--
ENSG00000178445	6.599	6.765	6.886	6.639	7.675	6.646	502	517	379	392	491	369	GLDC	glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K00281;K00281;K00281;K00281	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0005960//glycine cleavage complex	GO:0003824//catalytic activity;GO:0004375//glycine dehydrogenase (decarboxylating) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016594//glycine binding;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0070280//pyridoxal binding	GO:0006520//cellular amino acid metabolic process;GO:0006544//glycine metabolic process;GO:0006546//glycine catabolic process;GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0022900//electron transport chain;GO:0036255//response to methylamine;GO:1903442//response to lipoic acid;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000178449	28.717	25.866	31.553	30.506	23.728	35.702	292	265	238	229	203	264	COX14	cytochrome c oxidase assembly factor COX14 [Source:HGNC Symbol;Acc:HGNC:28216]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18181	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000178460	0.32	0.329	0.57	0.383	0.435	0.522	30	25	37	20	34	34	MCMDC2	minichromosome maintenance domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26368]	-	-	-	-	-	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0000727//double-strand break repair via break-induced replication;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:0051321//meiotic cell cycle	--
ENSG00000178462	0	0	0	0	0	0	0	0	0	0	0	0	TUBAL3	tubulin alpha like 3 [Source:HGNC Symbol;Acc:HGNC:23534]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process	--
ENSG00000178467	46.719	47.312	45.591	48.798	48.747	44.741	1608	1618	1186	1280	1467	1106	P4HTM	"prolyl 4-hydroxylase, transmembrane [Source:HGNC Symbol;Acc:HGNC:28858]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0045646//regulation of erythrocyte differentiation	--
ENSG00000178473	0	0	0	0	0	0	0	0	0	0	0	0	UCN3	urocortin 3 [Source:HGNC Symbol;Acc:HGNC:17781]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05257	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030424//axon;GO:0043005//neuron projection;GO:0043196//varicosity;GO:0043679//axon terminus	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0051429//corticotropin-releasing hormone receptor binding;GO:0051431//corticotropin-releasing hormone receptor 2 binding	GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007586//digestion;GO:0009749//response to glucose;GO:0009755//hormone-mediated signaling pathway;GO:0031669//cellular response to nutrient levels;GO:0032024//positive regulation of insulin secretion;GO:0035902//response to immobilization stress;GO:0042594//response to starvation;GO:0045838//positive regulation of membrane potential;GO:0051412//response to corticosterone;GO:0071456//cellular response to hypoxia	--
ENSG00000178498	20.301	24.321	24.573	23.558	23.226	24.991	783	931	685	644	783	663	DTX3	deltex E3 ubiquitin ligase 3 [Source:HGNC Symbol;Acc:HGNC:24457]	Environmental Information Processing	Signal transduction	ko04330//Notch signaling pathway	K06058	GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination	--
ENSG00000178502	2.091	1.581	2.196	1.592	1.457	1.531	321	244	249	181	189	171	KLHL11	kelch like family member 11 [Source:HGNC Symbol;Acc:HGNC:19008]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000178522	0	0	0	0	0	0	0	0	0	0	0	0	AMBN	ameloblastin [Source:HGNC Symbol;Acc:HGNC:452]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0030345//structural constituent of tooth enamel	GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0031214//biomineral tissue development;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth	--
ENSG00000178531	12.745	13.843	11.768	10.576	9.595	7.928	327	357	223	201	208	148	CTXN1	cortexin 1 [Source:HGNC Symbol;Acc:HGNC:31108]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000178537	5.833	6.68	6.405	6.223	5.609	7.386	214	244	172	170	174	196	SLC25A20	solute carrier family 25 member 20 [Source:HGNC Symbol;Acc:HGNC:1421]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K15109	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015227//acyl carnitine transmembrane transporter activity	GO:0001701//in utero embryonic development;GO:0006853//carnitine shuttle;GO:0006869//lipid transport;GO:1902603//carnitine transmembrane transport;GO:1902616//acyl carnitine transmembrane transport	--
ENSG00000178538	0.454	0.468	0.501	0.193	0.348	0.37	54	56	44	17	35	32	CA8	carbonic anhydrase 8 [Source:HGNC Symbol;Acc:HGNC:1382]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000178562	0	0	0	0	0	0	0	0	0	0	0	0	CD28	CD28 molecule [Source:HGNC Symbol;Acc:HGNC:1653]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Immune disease;Immune disease;Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune disease;Immune system;Immune system;Immune disease;Cancer: overview;Endocrine and metabolic disease;Immune disease	ko05322//Systemic lupus erythematosus;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05162//Measles;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06470;K06470;K06470;K06470;K06470;K06470;K06470;K06470;K06470;K06470;K06470;K06470	GO:0001772//immunological synapse;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098636//protein complex involved in cell adhesion	GO:0002020//protease binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding	GO:0001819//positive regulation of cytokine production;GO:0002863//positive regulation of inflammatory response to antigenic stimulus;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007166//cell surface receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0031295//T cell costimulation;GO:0032733//positive regulation of interleukin-10 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0042129//regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045060//negative thymic T cell selection;GO:0045066//regulatory T cell differentiation;GO:0045070//positive regulation of viral genome replication;GO:0045589//regulation of regulatory T cell differentiation;GO:0045727//positive regulation of translation;GO:0045840//positive regulation of mitotic nuclear division;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0050852//T cell receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0097190//apoptotic signaling pathway	--
ENSG00000178567	5.996	5.016	4.834	5.175	4.938	4.358	1006	846	599	508	700	532	EPM2AIP1	EPM2A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19735]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0098554//cytoplasmic side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032868//response to insulin;GO:0045725//positive regulation of glycogen biosynthetic process;GO:2000467//positive regulation of glycogen (starch) synthase activity	--
ENSG00000178568	5.078	4.454	3.381	2.694	3.111	3.321	1196	951	626	428	659	563	ERBB4	erb-b2 receptor tyrosine kinase 4 [Source:HGNC Symbol;Acc:HGNC:3432]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Cancer: overview;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05205//Proteoglycans in cancer;ko04012//ErbB signaling pathway	K05085;K05085;K05085;K05085;K05085;K05085	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane;GO:0098590//plasma membrane region;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099056//integral component of presynaptic membrane;GO:0099061//integral component of postsynaptic density membrane	GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038131//neuregulin receptor activity;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity	"GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0007507//heart development;GO:0007595//lactation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021551//central nervous system morphogenesis;GO:0021889//olfactory bulb interneuron differentiation;GO:0030334//regulation of cell migration;GO:0033674//positive regulation of kinase activity;GO:0038130//ERBB4 signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060644//mammary gland epithelial cell differentiation;GO:0060749//mammary gland alveolus development;GO:0061026//cardiac muscle tissue regeneration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072046//establishment of planar polarity involved in nephron morphogenesis;GO:2000010//positive regulation of protein localization to cell surface"	--
ENSG00000178573	10.795	10.569	10.014	11.246	10.263	11.649	1220	1193	803	932	959	952	MAF	MAF bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:6776]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Immune disease	ko05202//Transcriptional misregulation in cancer;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K09035;K09035;K09035	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002088//lens development in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0032330//regulation of chondrocyte differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048468//cell development;GO:0048839//inner ear development;GO:0070306//lens fiber cell differentiation;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000178585	13.91	13.196	14.59	15.207	13.716	12.826	680	704	520	555	569	433	CTNNBIP1	catenin beta interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16913]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04493	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex;GO:1990711//beta-catenin-ICAT complex	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0070016//armadillo repeat domain binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0009952//anterior/posterior pattern specification;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045657//positive regulation of monocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000178586	0	0	0	0	0	0	0	0	0	0	0	0	OR6B3	olfactory receptor family 6 subfamily B member 3 [Source:HGNC Symbol;Acc:HGNC:15042]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000178591	0	0	0	0	0	0	0	0	0	0	0	0	DEFB125	defensin beta 125 [Source:HGNC Symbol;Acc:HGNC:18105]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000178597	0	0	0	0	0.012	0	0	0	0	0	1	0	PSAPL1	prosaposin like 1 [Source:HGNC Symbol;Acc:HGNC:33131]	Cellular Processes;Metabolism	Transport and catabolism;Lipid metabolism	ko04142//Lysosome;ko00600//Sphingolipid metabolism	K12382;K12382	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005829//cytosol	-	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0060736//prostate gland growth;GO:0060742//epithelial cell differentiation involved in prostate gland development	--
ENSG00000178602	0	0	0.405	0	0	0	0	0	4	0	0	0	OTOS	otospiralin [Source:HGNC Symbol;Acc:HGNC:22644]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0007605//sensory perception of sound	--
ENSG00000178605	12.11	12.375	14.651	15.256	15.65	16.887	479	492	428	447	523	486	GTPBP6	GTP binding protein 6 (putative) [Source:HGNC Symbol;Acc:HGNC:30189]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005525//GTP binding;GO:0043022//ribosome binding;GO:0046872//metal ion binding	-	--
ENSG00000178607	1.418	1.505	1.495	1.3	1.993	1.433	222	238	176	155	264	166	ERN1	endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Cardiovascular disease;Folding, sorting and degradation;Endocrine and metabolic disease;Transport and catabolism;Neurodegenerative disease;Cell growth and death"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05012//Parkinson disease;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04210//Apoptosis	K08852;K08852;K08852;K08852;K08852;K08852;K08852;K08852;K08852;K08852;K08852	GO:0005637//nuclear inner membrane;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:1990332//Ire1 complex;GO:1990597//AIP1-IRE1 complex;GO:1990604//IRE1-TRAF2-ASK1 complex;GO:1990630//IRE1-RACK1-PP2A complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004540//ribonuclease activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0030544//Hsp70 protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0051879//Hsp90 protein binding;GO:0106310//protein serine kinase activity	"GO:0001935//endothelial cell proliferation;GO:0006379//mRNA cleavage;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006986//response to unfolded protein;GO:0008152//metabolic process;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0033120//positive regulation of RNA splicing;GO:0034620//cellular response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036289//peptidyl-serine autophosphorylation;GO:0036498//IRE1-mediated unfolded protein response;GO:0043507//positive regulation of JUN kinase activity;GO:0046777//protein autophosphorylation;GO:0070054//mRNA splicing, via endonucleolytic cleavage and ligation;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070301//cellular response to hydrogen peroxide;GO:0071333//cellular response to glucose stimulus;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0098787//mRNA cleavage involved in mRNA processing;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1901142//insulin metabolic process;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1990579//peptidyl-serine trans-autophosphorylation"	--
ENSG00000178623	0.481	0.189	0.059	0.16	0.115	0.058	22	9	3	8	7	3	GPR35	G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04276	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1904456//negative regulation of neuronal action potential	--
ENSG00000178645	0.061	0.088	0.04	0.027	0.018	0	3	6	2	1	1	0	C10orf53	chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421]	-	-	-	-	-	-	-	--
ENSG00000178662	2.511	1.835	1.734	1.331	1.62	1.406	601	436	280	240	268	249	CSRNP3	cysteine and serine rich nuclear protein 3 [Source:HGNC Symbol;Acc:HGNC:30729]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II	CSRNP_N
ENSG00000178665	2.7	2.835	2.788	1.873	2.036	1.931	180.63	171.02	120.3	81.95	101.73	89.95	ZNF713	zinc finger protein 713 [Source:HGNC Symbol;Acc:HGNC:22043]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178685	3.809	5.319	4.657	6.02	4.877	3.43	218	271	182	200	227	163	PARP10	poly(ADP-ribose) polymerase family member 10 [Source:HGNC Symbol;Acc:HGNC:25895]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0140297//DNA-binding transcription factor binding;GO:1990404//protein ADP-ribosylase activity	"GO:0006281//DNA repair;GO:0006471//protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus;GO:0010629//negative regulation of gene expression;GO:0010847//regulation of chromatin assembly;GO:0019082//viral protein processing;GO:0019985//translesion synthesis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0045071//negative regulation of viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048147//negative regulation of fibroblast proliferation;GO:0070212//protein poly-ADP-ribosylation;GO:0070213//protein auto-ADP-ribosylation;GO:0140289//protein mono-ADP-ribosylation;GO:1900045//negative regulation of protein K63-linked ubiquitination"	--
ENSG00000178690	0	0	0	0	0	0	0	0	0	0	0	0	DYNAP	dynactin associated protein [Source:HGNC Symbol;Acc:HGNC:26808]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0008284//positive regulation of cell population proliferation;GO:0032148//activation of protein kinase B activity;GO:0042981//regulation of apoptotic process;GO:1901625//cellular response to ergosterol	--
ENSG00000178691	11.001	7.291	6.913	4.936	6.275	7.312	995	665	476	334	489	485	SUZ12	SUZ12 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:17101]	-	-	-	-	GO:0001739//sex chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005677//chromatin silencing complex;GO:0005730//nucleolus;GO:0016604//nuclear body;GO:0032993//protein-DNA complex;GO:0035098//ESC/E(Z) complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0031490//chromatin DNA binding;GO:0035064//methylated histone binding;GO:0042054//histone methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006807//nitrogen compound metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0016571//histone methylation;GO:0016574//histone ubiquitination;GO:0044238//primary metabolic process;GO:0045596//negative regulation of cell differentiation;GO:0048709//oligodendrocyte differentiation;GO:0050790//regulation of catalytic activity;GO:0071704//organic substance metabolic process	--
ENSG00000178694	1.924	1.199	1.117	0.931	0.967	1.278	175	133	110	92	109	124	NSUN3	NOP2/Sun RNA methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:26208]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0016740//transferase activity	GO:0001510//RNA methylation;GO:0002127//tRNA wobble base cytosine methylation;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:0070129//regulation of mitochondrial translation	--
ENSG00000178695	6.569	5.997	4.662	5.912	6.237	4.955	849	779	445	566	681	466	KCTD12	potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0051260//protein homooligomerization	--
ENSG00000178700	2.513	2.633	2.37	2.327	2.442	2.114	201	196	140	137	165	105	DHFR2	dihydrofolate reductase 2 [Source:HGNC Symbol;Acc:HGNC:27309]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko01523//Antifolate resistance;ko00790//Folate biosynthesis;ko00670//One carbon pool by folate	K00287;K00287;K00287;K00287	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane	GO:0003729//mRNA binding;GO:0004146//dihydrofolate reductase activity;GO:0016491//oxidoreductase activity;GO:0033560//folate reductase activity;GO:0050661//NADP binding	GO:0006545//glycine biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0046105//thymidine biosynthetic process;GO:0046452//dihydrofolate metabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0046655//folic acid metabolic process	--
ENSG00000178718	3.501	3.32	3.52	6.522	5.428	5.599	171	163	127	236	224	199	RPP25	ribonuclease P and MRP subunit p25 [Source:HGNC Symbol;Acc:HGNC:30361]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14525	GO:0000172//ribonuclease MRP complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030677//ribonuclease P complex;GO:0030681//multimeric ribonuclease P complex;GO:0034451//centriolar satellite	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding	"GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000178719	122.412	122.099	126.597	141.356	135.06	131.374	4500	4694	3555	4043	4417	3556	GRINA	glutamate ionotropic receptor NMDA type subunit associated protein 1 [Source:HGNC Symbol;Acc:HGNC:4589]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000178726	1.874	1.448	0.792	2.014	1.61	2.116	157	122	49	125	114	129	THBD	thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784]	Human Diseases;Human Diseases;Organismal Systems	Cardiovascular disease;Endocrine and metabolic disease;Immune system	ko05418//Fluid shear stress and atherosclerosis;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04610//Complement and coagulation cascades	K03907;K03907;K03907	GO:0005615//extracellular space;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016327//apicolateral plasma membrane;GO:1905370//serine-type endopeptidase complex	GO:0004888//transmembrane signaling receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	"GO:0006508//proteolysis;GO:0007565//female pregnancy;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010165//response to X-ray;GO:0010544//negative regulation of platelet activation;GO:0030195//negative regulation of blood coagulation;GO:0031638//zymogen activation;GO:0032496//response to lipopolysaccharide;GO:0051591//response to cAMP;GO:0051918//negative regulation of fibrinolysis;GO:0072377//blood coagulation, common pathway"	--
ENSG00000178732	0	0	0	0	0.016	0	0	0	0	0	1	0	GP5	glycoprotein V platelet [Source:HGNC Symbol;Acc:HGNC:4443]	Organismal Systems;Organismal Systems;Environmental Information Processing	Immune system;Immune system;Signaling molecules and interaction	ko04640//Hematopoietic cell lineage;ko04611//Platelet activation;ko04512//ECM-receptor interaction	K06260;K06260;K06260	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:1990779//glycoprotein Ib-IX-V complex	GO:0005515//protein binding	"GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis;GO:0010572//positive regulation of platelet activation;GO:0035855//megakaryocyte development;GO:0051209//release of sequestered calcium ion into cytosol"	--
ENSG00000178741	66.766	62.183	70.95	86.039	68.537	81.129	816	772	643	800	717	725	COX5A	cytochrome c oxidase subunit 5A [Source:HGNC Symbol;Acc:HGNC:2267]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264;K02264	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0046872//metal ion binding	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000178750	0	0.083	0	0.17	0	0	0	2	0	3	0	0	STX19	syntaxin 19 [Source:HGNC Symbol;Acc:HGNC:19300]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08487	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0048787//presynaptic active zone membrane	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0048278//vesicle docking	--
ENSG00000178752	0.542	0.409	0.267	0.31	0.093	0.132	12	18	12	6	1	4	ERFE	erythroferrone [Source:HGNC Symbol;Acc:HGNC:26727]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006879//cellular iron ion homeostasis;GO:0007165//signal transduction;GO:0019217//regulation of fatty acid metabolic process;GO:0045721//negative regulation of gluconeogenesis;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:2000193//positive regulation of fatty acid transport	--
ENSG00000178761	21.204	20.827	24.648	23.725	20.665	25.48	1198.51	1123.61	1015.33	938.21	974.44	1109.67	FAM219B	family with sequence similarity 219 member B [Source:HGNC Symbol;Acc:HGNC:24695]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000178764	11.928	12.23	10.523	9.286	11.644	11.664	1079	1060	703	610	877	668	ZHX2	zinc fingers and homeoboxes 2 [Source:HGNC Symbol;Acc:HGNC:18513]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006402//mRNA catabolic process;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0035019//somatic stem cell population maintenance;GO:0045665//negative regulation of neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060040//retinal bipolar neuron differentiation"	Homeobox
ENSG00000178772	0	0	0	0	0	0	0	0	0	0	0	0	CPN2	carboxypeptidase N subunit 2 [Source:HGNC Symbol;Acc:HGNC:2313]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005515//protein binding;GO:0030234//enzyme regulator activity	GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization	--
ENSG00000178773	0.534	0.213	0.548	0.56	0.842	0.76	13	9	6	21	30	28	CPNE7	copine 7 [Source:HGNC Symbol;Acc:HGNC:2320]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0071277//cellular response to calcium ion	--
ENSG00000178776	2.919	3.67	1.047	0.454	1.195	0.578	34	43	9	4	12	5	C5orf46	chromosome 5 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:33768]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000178789	0	0	0	0	0	0	0	0	0	0	0	0	CD300LB	CD300 molecule like family member b [Source:HGNC Symbol;Acc:HGNC:30811]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002376//immune system process	--
ENSG00000178795	0.092	0.058	0.078	0.078	0.046	0.132	5	3	3	3	2	5	GDPD4	glycerophosphodiester phosphodiesterase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24849]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process	--
ENSG00000178796	0	0	0	0	0	0	0	0	0	0	0	0	RIIAD1	regulatory subunit of type II PKA R-subunit domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26686]	-	-	-	-	-	-	-	--
ENSG00000178802	30.2	32.027	31.538	30.353	32.557	32.377	905.49	1023.39	774.67	715.79	874.56	774.33	MPI	mannose phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:7216]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K01809;K01809;K01809	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004476//mannose-6-phosphate isomerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016853//isomerase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0009298//GDP-mannose biosynthetic process;GO:0061611//mannose to fructose-6-phosphate metabolic process	--
ENSG00000178804	0	0	0	0	0	0	0	0	0	0	0	0	H1-8	H1.8 linker histone [Source:HGNC Symbol;Acc:HGNC:18463]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0031492//nucleosomal DNA binding	GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0044030//regulation of DNA methylation;GO:0045910//negative regulation of DNA recombination;GO:0051321//meiotic cell cycle;GO:2000737//negative regulation of stem cell differentiation	--
ENSG00000178809	0.823	0.632	0.874	1.097	0.8	0.472	24	17.69	18.37	22.95	18.69	9.81	TRIM73	tripartite motif containing 73 [Source:HGNC Symbol;Acc:HGNC:18162]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000178814	7.268	7.219	8.817	9.293	8.872	8.258	606	605	543	574	625	501	OPLAH	"5-oxoprolinase, ATP-hydrolysing [Source:HGNC Symbol;Acc:HGNC:8149]"	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K01469;K01469	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017168//5-oxoprolinase (ATP-hydrolyzing) activity;GO:0042802//identical protein binding	GO:0006749//glutathione metabolic process	--
ENSG00000178821	0.516	0.3	0.14	0.278	0.613	0.709	10	7	2	4	12	10	TMEM52	transmembrane protein 52 [Source:HGNC Symbol;Acc:HGNC:27916]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000178826	8.966	10.284	10.842	10.623	9.34	9.172	277	326	257	246	249	221	TMEM139	transmembrane protein 139 [Source:HGNC Symbol;Acc:HGNC:22058]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000178828	0	0	0	0	0	0	0	0	0	0	0	0	RNF186	ring finger protein 186 [Source:HGNC Symbol;Acc:HGNC:25978]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0035519//protein K29-linked ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070534//protein K63-linked ubiquitination;GO:0070585//protein localization to mitochondrion	--
ENSG00000178852	0.087	0	0.075	0.038	0	0	6.81	0	4	2	0	0	EFCAB13	EF-hand calcium binding domain 13 [Source:HGNC Symbol;Acc:HGNC:26864]	-	-	-	-	-	-	-	--
ENSG00000178860	0.887	0.858	0.234	0.333	0.292	0.068	36	35	7	10	10	2	MSC	musculin [Source:HGNC Symbol;Acc:HGNC:7321]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003161//cardiac conduction system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0014707//branchiomeric skeletal muscle development;GO:0032502//developmental process;GO:0060021//roof of mouth development;GO:0060539//diaphragm development;GO:1990830//cellular response to leukemia inhibitory factor"	bHLH
ENSG00000178878	11.528	10.57	12.212	5.441	6.742	7.913	1019.11	975.29	804.04	383.08	530.78	510.13	APOLD1	apolipoprotein L domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25268]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008289//lipid binding	GO:0001525//angiogenesis;GO:0006869//lipid transport;GO:0030154//cell differentiation;GO:0042157//lipoprotein metabolic process;GO:0045601//regulation of endothelial cell differentiation	--
ENSG00000178882	0.563	0.498	0.394	0.212	1.152	0.123	28.09	24	15	7	21	4	RFLNA	refilin A [Source:HGNC Symbol;Acc:HGNC:27051]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0032432//actin filament bundle	GO:0005515//protein binding;GO:0031005//filamin binding	GO:0048705//skeletal system morphogenesis;GO:0061181//regulation of chondrocyte development;GO:0061182//negative regulation of chondrocyte development;GO:0061572//actin filament bundle organization;GO:1900158//negative regulation of bone mineralization involved in bone maturation	--
ENSG00000178896	14.023	13.633	18.633	23.561	18.436	17.458	244	240	239	303	272	224	EXOSC4	exosome component 4 [Source:HGNC Symbol;Acc:HGNC:18189]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K11600	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0101019//nucleolar exosome (RNase complex);GO:1902494//catalytic complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	"GO:0000460//maturation of 5.8S rRNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034475//U4 snRNA 3'-end processing;GO:0045006//DNA deamination;GO:0051252//regulation of RNA metabolic process;GO:0051607//defense response to virus;GO:0071028//nuclear mRNA surveillance;GO:0071044//histone mRNA catabolic process;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic"	--
ENSG00000178904	10.525	8.691	11.714	9.564	9.467	9.259	1289	1075	1051	780	972	825	DPY19L3	dpy-19 like C-mannosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:27120]	-	-	-	-	GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	--
ENSG00000178913	39.283	38.53	37.693	32.057	31.668	36.313	1870	1807	1251	1048	1165	1198	TAF7	TATA-box binding protein associated factor 7 [Source:HGNC Symbol;Acc:HGNC:11541]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03132	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0033276//transcription factor TFTC complex;GO:0071339//MLL1 complex	GO:0000976//transcription cis-regulatory region binding;GO:0001097//TFIIH-class transcription factor complex binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0035035//histone acetyltransferase binding;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0046982//protein heterodimerization activity;GO:0061628//H3K27me3 modified histone binding;GO:0106140//P-TEFb complex binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000296//spermine transport;GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0035067//negative regulation of histone acetylation;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043966//histone H3 acetylation;GO:0045344//negative regulation of MHC class I biosynthetic process;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0090241//negative regulation of histone H4 acetylation"	--
ENSG00000178917	0.711	1.797	1.741	1.26	1.816	1.685	29	63	43	35	56	50	ZNF852	zinc finger protein 852 [Source:HGNC Symbol;Acc:HGNC:27713]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178919	0.028	0.041	0	0	0	0	2	3	0	0	0	0	FOXE1	forkhead box E1 [Source:HGNC Symbol;Acc:HGNC:3806]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006590//thyroid hormone generation;GO:0009653//anatomical structure morphogenesis;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0030878//thyroid gland development;GO:0031069//hair follicle morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0048562//embryonic organ morphogenesis;GO:0060021//roof of mouth development;GO:0060022//hard palate development;GO:0060023//soft palate development;GO:0060465//pharynx development;GO:1904888//cranial skeletal system development"	Fork_head
ENSG00000178921	9.194	10.18	11.506	9.698	11.67	9.777	998	1054	850	800	998	759	PFAS	phosphoribosylformylglycinamidine synthase [Source:HGNC Symbol;Acc:HGNC:8863]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K01952;K01952	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004642//phosphoribosylformylglycinamidine synthase activity;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding	GO:0006164//purine nucleotide biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0044208//'de novo' AMP biosynthetic process;GO:0097065//anterior head development;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000178922	19.825	17.172	18.902	24.466	20.69	23.496	408.49	363.11	293.3	390.45	355.11	367.55	HYI	hydroxypyruvate isomerase (putative) [Source:HGNC Symbol;Acc:HGNC:26948]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00630//Glyoxylate and dicarboxylate metabolism	K01816;K01816	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008903//hydroxypyruvate isomerase activity;GO:0016853//isomerase activity	GO:0008150//biological_process;GO:0046487//glyoxylate metabolic process	--
ENSG00000178927	19.136	19.929	20.175	18.633	22.389	21.42	732	752	569	532	629	493	CYBC1	cytochrome b-245 chaperone 1 [Source:HGNC Symbol;Acc:HGNC:28672]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002376//immune system process;GO:0045087//innate immune response;GO:0045728//respiratory burst after phagocytosis	--
ENSG00000178928	0	0	0	0	0	0	0	0	0	0	0	0	TPRX1	tetrapeptide repeat homeobox 1 [Source:HGNC Symbol;Acc:HGNC:32174]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000178934	0	0	0	0	0	0	0	0	0	0	0	0	LGALS7B	galectin 7B [Source:HGNC Symbol;Acc:HGNC:34447]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	"GO:0006915//apoptotic process;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0010628//positive regulation of gene expression;GO:0032689//negative regulation of interferon-gamma production;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000178935	1.416	1.695	2.42	1.405	1.542	1.976	69.09	80.94	72.1	50.78	59.3	67.47	ZNF552	zinc finger protein 552 [Source:HGNC Symbol;Acc:HGNC:26135]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000178947	2.858	3.256	2.621	4.418	4.081	2.939	310	355	210	355	374	232	SMIM10L2A	small integral membrane protein 10 like 2A [Source:HGNC Symbol;Acc:HGNC:34499]	-	-	-	-	-	-	-	--
ENSG00000178950	18.607	20.265	24.083	23.139	22.319	26.543	1401	1604	1290	1342	1436	1285	GAK	cyclin G associated kinase [Source:HGNC Symbol;Acc:HGNC:4113]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0098793//presynapse	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030276//clathrin binding;GO:0030332//cyclin binding;GO:0051087//chaperone binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006898//receptor-mediated endocytosis;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0007049//cell cycle;GO:0010977//negative regulation of neuron projection development;GO:0016191//synaptic vesicle uncoating;GO:0016310//phosphorylation;GO:0034067//protein localization to Golgi apparatus;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0072318//clathrin coat disassembly;GO:0072583//clathrin-dependent endocytosis;GO:0072659//protein localization to plasma membrane;GO:0090160//Golgi to lysosome transport;GO:1905224//clathrin-coated pit assembly	--
ENSG00000178951	6.725	6.094	6.136	6.316	6.448	6.357	561	464	409	363	448	347	ZBTB7A	zinc finger and BTB domain containing 7A [Source:HGNC Symbol;Acc:HGNC:18078]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0035861//site of double-strand break;GO:0070418//DNA-dependent protein kinase complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001222//transcription corepressor binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006110//regulation of glycolytic process;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034504//protein localization to nucleus;GO:0042981//regulation of apoptotic process;GO:0043249//erythrocyte maturation;GO:0045444//fat cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0097680//double-strand break repair via classical nonhomologous end joining;GO:2000677//regulation of transcription regulatory region DNA binding"	ZBTB
ENSG00000178952	93.714	97.337	106.308	123.103	107.688	106.491	3909	4081	3270	3799	3795	3232	TUFM	"Tu translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12420]"	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0045471//response to ethanol;GO:0070125//mitochondrial translational elongation	--
ENSG00000178965	0.025	0.033	0	0	0.008	0.009	2	5	0	0	1	1	ERICH3	glutamate rich 3 [Source:HGNC Symbol;Acc:HGNC:25346]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000178966	12.084	9.928	9.009	6.024	7.208	7.485	835	690	457	306	418	374	RMI1	RecQ mediated genome instability 1 [Source:HGNC Symbol;Acc:HGNC:25764]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10990	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0031422//RecQ family helicase-topoisomerase III complex	GO:0000166//nucleotide binding;GO:0005515//protein binding	GO:0000712//resolution of meiotic recombination intermediates;GO:0000724//double-strand break repair via homologous recombination;GO:0002021//response to dietary excess;GO:0002023//reduction of food intake in response to dietary excess;GO:0006260//DNA replication;GO:0009749//response to glucose;GO:0035264//multicellular organism growth;GO:0042593//glucose homeostasis;GO:0071139//resolution of recombination intermediates	--
ENSG00000178971	3.84	5.29	3.716	5.998	5.437	3.835	350	433	332	275	333	282	CTC1	CST telomere replication complex component 1 [Source:HGNC Symbol;Acc:HGNC:26169]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:1990879//CST complex"	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0098505//G-rich strand telomeric DNA binding	GO:0000723//telomere maintenance;GO:0006974//cellular response to DNA damage stimulus;GO:0007568//aging;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0010833//telomere maintenance via telomere lengthening;GO:0016233//telomere capping;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0035264//multicellular organism growth;GO:0045740//positive regulation of DNA replication;GO:0048146//positive regulation of fibroblast proliferation;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048539//bone marrow development;GO:0051276//chromosome organization;GO:0071425//hematopoietic stem cell proliferation;GO:0090399//replicative senescence	--
ENSG00000178974	10.902	11.25	11.855	10.845	9.442	12.648	755	781	600	556	551	633	FBXO34	F-box protein 34 [Source:HGNC Symbol;Acc:HGNC:20201]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000178980	296.169	307.571	333.352	340.702	307.104	304.427	4635	4821	3826	3931	4044	3444	-	-	-	-	-	-	-	-	-	-
ENSG00000178982	180.969	199.165	204.038	245.391	224.407	209.921	2674	2966	2170	2707	2740	2230	EIF3K	eukaryotic translation initiation factor 3 subunit K [Source:HGNC Symbol;Acc:HGNC:24656]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0043022//ribosome binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation	--
ENSG00000178988	44.117	43.132	43.601	39.596	38.152	47.575	1444	1419	1054	960	1055	1133	MRFAP1L1	Morf4 family associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28796]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000178996	7.578	7.08	6.794	5.994	5.944	7.525	821	771	515	481	544	557	SNX18	sorting nexin 18 [Source:HGNC Symbol;Acc:HGNC:19245]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K17923	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding"	GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0006897//endocytosis;GO:0007049//cell cycle;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0036089//cleavage furrow formation;GO:0043547//positive regulation of GTPase activity;GO:0051301//cell division;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000178997	0	0	0	0	0	0.023	0	0	0	0	0	1	EXD1	exonuclease 3'-5' domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28507]	-	-	-	-	GO:0005737//cytoplasm;GO:0043186//P granule;GO:1990923//PET complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0042803//protein homodimerization activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0051321//meiotic cell cycle	--
ENSG00000178999	0.165	0.411	0.28	0.804	0.321	0.596	4	10	5	11	7	8	AURKB	aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0010369//chromocenter;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031616//spindle pole centrosome;GO:0032133//chromosome passenger complex;GO:0051233//spindle midzone;GO:0097431//mitotic spindle pole;GO:1990023//mitotic spindle midzone"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0035174//histone serine kinase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000278//mitotic cell cycle;GO:0000281//mitotic cytokinesis;GO:0001934//positive regulation of protein phosphorylation;GO:0002903//negative regulation of B cell apoptotic process;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007051//spindle organization;GO:0007052//mitotic spindle organization;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007568//aging;GO:0008283//cell population proliferation;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0009838//abscission;GO:0016310//phosphorylation;GO:0016570//histone modification;GO:0032091//negative regulation of protein binding;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0032465//regulation of cytokinesis;GO:0032466//negative regulation of cytokinesis;GO:0032467//positive regulation of cytokinesis;GO:0034501//protein localization to kinetochore;GO:0034644//cellular response to UV;GO:0036089//cleavage furrow formation;GO:0043988//histone H3-S28 phosphorylation;GO:0044878//mitotic cytokinesis checkpoint signaling;GO:0046777//protein autophosphorylation;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division;GO:0051973//positive regulation of telomerase activity;GO:0051983//regulation of chromosome segregation;GO:0062033//positive regulation of mitotic sister chromatid segregation;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1901970//positive regulation of mitotic sister chromatid separation;GO:1902425//positive regulation of attachment of mitotic spindle microtubules to kinetochore;GO:1903490//positive regulation of mitotic cytokinesis;GO:1904355//positive regulation of telomere capping;GO:1905116//positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	--
ENSG00000179002	0	0	0	0	0	0	0	0	0	0	0	0	TAS1R2	taste 1 receptor member 2 [Source:HGNC Symbol;Acc:HGNC:14905]	Organismal Systems;Organismal Systems	Sensory system;Digestive system	ko04742//Taste transduction;ko04973//Carbohydrate digestion and absorption	K04625;K04625	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:1903767//sweet taste receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033041//sweet taste receptor activity	GO:0001582//detection of chemical stimulus involved in sensory perception of sweet taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050916//sensory perception of sweet taste	--
ENSG00000179008	0.177	0.367	0.303	0.196	0.355	0.024	8	9	5	2	3	1	C14orf39	chromosome 14 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:19849]	-	-	-	-	GO:0000801//central element;GO:0005575//cellular_component;GO:0005694//chromosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0010705//meiotic DNA double-strand break processing involved in reciprocal meiotic recombination;GO:0048477//oogenesis;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0051321//meiotic cell cycle	--
ENSG00000179010	234.606	239.577	242.203	249.986	236.463	269.35	7716	7892	5892	6102	6545	6403	MRFAP1	Morf4 family associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24549]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000179021	11.287	10.609	10.217	9.575	8.17	10.079	491	466	328	317	305	313	C3orf38	chromosome 3 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28384]	-	-	-	-	GO:0005634//nucleus	GO:0003674//molecular_function	GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process	--
ENSG00000179023	2.599	2.881	3.118	3.174	3.348	3.546	272	303	241	246	296	270	KLHDC7A	kelch domain containing 7A [Source:HGNC Symbol;Acc:HGNC:26791]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000179029	5.49	8.441	8.806	7.94	4.984	6.492	189	251	182	193	158	143	TMEM107	transmembrane protein 107 [Source:HGNC Symbol;Acc:HGNC:28128]	-	-	-	-	GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0003127//detection of nodal flow;GO:0007368//determination of left/right symmetry;GO:0010468//regulation of gene expression;GO:0021532//neural tube patterning;GO:0030030//cell projection organization;GO:0042733//embryonic digit morphogenesis;GO:0044782//cilium organization;GO:0060021//roof of mouth development;GO:0060271//cilium assembly;GO:0097094//craniofacial suture morphogenesis;GO:1904491//protein localization to ciliary transition zone;GO:1905515//non-motile cilium assembly	--
ENSG00000179041	6.195	5.745	4.782	6.13	6.204	7.011	221	206	126	162	187	182	RRS1	ribosome biogenesis regulator 1 homolog [Source:HGNC Symbol;Acc:HGNC:17083]	-	-	-	-	"GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0030687//preribosome, large subunit precursor"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008097//5S rRNA binding	"GO:0000027//ribosomal large subunit assembly;GO:0000055//ribosomal large subunit export from nucleus;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002244//hematopoietic progenitor cell differentiation;GO:0007080//mitotic metaphase plate congression;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902570//protein localization to nucleolus"	--
ENSG00000179044	0.065	0	0.029	0.059	0	0	3	0	1	2	0	0	EXOC3L1	exocyst complex component 3 like 1 [Source:HGNC Symbol;Acc:HGNC:27540]	-	-	-	-	GO:0000145//exocyst;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle	GO:0000149//SNARE binding;GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006887//exocytosis;GO:0030072//peptide hormone secretion;GO:0051601//exocyst localization	--
ENSG00000179046	0	0	0	0	0	0.04	0	0	0	0	0	1	TRIML2	tripartite motif family like 2 [Source:HGNC Symbol;Acc:HGNC:26378]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0010033//response to organic substance;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032526//response to retinoic acid;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046596//regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000179051	29.527	33.796	33.597	28.945	29.661	31.398	2398	2621	1907	1721	1987	1844	RCC2	regulator of chromosome condensation 2 [Source:HGNC Symbol;Acc:HGNC:30297]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0031901//early endosome membrane;GO:0034506//chromosome, centromeric core domain;GO:1990023//mitotic spindle midzone"	GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031267//small GTPase binding	GO:0007049//cell cycle;GO:0007229//integrin-mediated signaling pathway;GO:0010762//regulation of fibroblast migration;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0030334//regulation of cell migration;GO:0034260//negative regulation of GTPase activity;GO:0045184//establishment of protein localization;GO:0048041//focal adhesion assembly;GO:0051301//cell division;GO:0051895//negative regulation of focal adhesion assembly;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore;GO:0072356//chromosome passenger complex localization to kinetochore;GO:0090630//activation of GTPase activity;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900027//regulation of ruffle assembly	--
ENSG00000179055	0	0	0	0	0	0	0	0	0	0	0	0	OR13D1	olfactory receptor family 13 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:14695]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179057	0.098	0.022	0.046	0.066	0	0	8.01	2	3	4	0	0	IGSF22	immunoglobulin superfamily member 22 [Source:HGNC Symbol;Acc:HGNC:26750]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000179058	0.06	0.118	0	0.201	0.072	0.123	2	4	0	5	1	3	C9orf50	chromosome 9 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:23677]	-	-	-	-	-	-	-	--
ENSG00000179059	0.078	0.103	0.028	0.084	0.195	0.267	4	5	1	3	8	10	ZFP42	ZFP42 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:30949]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0031519//PcG protein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0051321//meiotic cell cycle	zf-C2H2
ENSG00000179071	0.021	0	0	0	0	0.085	1	0	0	0	0	3	CCDC89	coiled-coil domain containing 89 [Source:HGNC Symbol;Acc:HGNC:26762]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000179083	0.137	0.061	0.083	0	0.072	0.104	9	4	4	0	4	5	FAM133A	family with sequence similarity 133 member A [Source:HGNC Symbol;Acc:HGNC:26748]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000179085	13.763	13.21	10.715	15.307	12.324	14.691	116	111	65	94	88	89	DPM3	"dolichyl-phosphate mannosyltransferase subunit 3, regulatory [Source:HGNC Symbol;Acc:HGNC:3007]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis	K09659;K09659	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031501//mannosyltransferase complex;GO:0033185//dolichol-phosphate-mannose synthase complex	GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006506//GPI anchor biosynthetic process;GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan;GO:0031647//regulation of protein stability;GO:0035268//protein mannosylation;GO:0035269//protein O-linked mannosylation;GO:0050790//regulation of catalytic activity	--
ENSG00000179088	0	0.231	0	0	0	0	0	4	0	0	0	0	C12orf42	chromosome 12 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:24729]	-	-	-	-	-	-	-	--
ENSG00000179091	46.673	47.119	59.577	64.54	63.198	67.318	1153	1170	1087	1181	1319	1210	CYC1	cytochrome c1 [Source:HGNC Symbol;Acc:HGNC:2579]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413;K00413	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008121//ubiquinol-cytochrome-c reductase activity;GO:0009055//electron transfer activity;GO:0020037//heme binding;GO:0046872//metal ion binding	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0033762//response to glucagon;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000179094	2.542	2.839	2.624	4.618	3.678	5.651	240	199	188	197	210	184	PER1	period circadian regulator 1 [Source:HGNC Symbol;Acc:HGNC:8845]	Organismal Systems;Organismal Systems	Environmental adaptation;Environmental adaptation	ko04713//Circadian entrainment;ko04710//Circadian rhythm	K21944;K21944	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0070888//E-box binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002028//regulation of sodium ion transport;GO:0007623//circadian rhythm;GO:0009416//response to light stimulus;GO:0009649//entrainment of circadian clock;GO:0010608//posttranscriptional regulation of gene expression;GO:0032922//circadian regulation of gene expression;GO:0042634//regulation of hair cycle;GO:0042752//regulation of circadian rhythm;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0048511//rhythmic process;GO:0051591//response to cAMP;GO:0070932//histone H3 deacetylation;GO:0097167//circadian regulation of translation;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1900744//regulation of p38MAPK cascade;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway"	--
ENSG00000179097	0	0	0	0	0	0	0	0	0	0	0	0	HTR1F	5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse;ko04742//Taste transduction	K04153;K04153;K04153;K04153	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission"	--
ENSG00000179104	2.988	2.466	2.177	2.808	3.081	3.387	302	254	175	190	234	243	TMTC2	transmembrane O-mannosyltransferase targeting cadherins 2 [Source:HGNC Symbol;Acc:HGNC:25440]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000030//mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006486//protein glycosylation;GO:0035269//protein O-linked mannosylation;GO:0055074//calcium ion homeostasis	--
ENSG00000179111	0	0	0	0	0	0	0	0	0	0	0	0	HES7	hes family bHLH transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:15977]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K09087	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007498//mesoderm development;GO:0009952//anterior/posterior pattern specification;GO:0036342//post-anal tail morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000179115	34.118	34.665	36.805	43.882	39.356	37.719	1281	1307	1020	1221	1249	1030	FARSA	phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01889	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009328//phenylalanine-tRNA ligase complex;GO:0016020//membrane	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004826//phenylalanine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0043039//tRNA aminoacylation;GO:0051290//protein heterotetramerization	--
ENSG00000179119	8.737	7.176	6.818	5.299	6.215	6.199	1015	838	585	456	610	524	SPTY2D1	SPT2 chromatin protein domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26818]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0001042//RNA polymerase I core binding;GO:0003677//DNA binding;GO:0042393//histone binding	"GO:0006334//nucleosome assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0010847//regulation of chromatin assembly;GO:0043486//histone exchange"	--
ENSG00000179133	0.231	0.208	0.093	0.11	0.129	0.22	11	9	4	5	2	10	C10orf67	chromosome 10 open reading frame 67 [Source:HGNC Symbol;Acc:HGNC:28716]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000179134	28.421	28.492	27.3	31.122	32.061	37.841	2179	2148	1537	1787	2115	1831	SAMD4B	sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:HGNC:25492]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0030371//translation repressor activity	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0017148//negative regulation of translation;GO:0043488//regulation of mRNA stability	--
ENSG00000179142	0	0	0	0	0	0	0	0	0	0	0	0	CYP11B2	cytochrome P450 family 11 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:2592]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko04925//Aldosterone synthesis and secretion;ko00140//Steroid hormone biosynthesis	K07433;K07433;K07433	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0004497//monooxygenase activity;GO:0004507//steroid 11-beta-monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0047783//corticosterone 18-monooxygenase activity"	GO:0002017//regulation of blood volume by renal aldosterone;GO:0003091//renal water homeostasis;GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0016125//sterol metabolic process;GO:0032342//aldosterone biosynthetic process;GO:0032870//cellular response to hormone stimulus;GO:0034650//cortisol metabolic process;GO:0034651//cortisol biosynthetic process;GO:0035865//cellular response to potassium ion;GO:0055075//potassium ion homeostasis;GO:0055078//sodium ion homeostasis;GO:0071375//cellular response to peptide hormone stimulus	--
ENSG00000179144	0	0	0	0	0	0	0	0	0	0	0	0	GIMAP7	"GTPase, IMAP family member 7 [Source:HGNC Symbol;Acc:HGNC:22404]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0046039//GTP metabolic process	--
ENSG00000179148	0	0	0	0	0	0	0	0	0	0	0	0	ALOXE3	arachidonate lipoxygenase 3 [Source:HGNC Symbol;Acc:HGNC:13743]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0050486//intramolecular transferase activity, transferring hydroxy groups;GO:0051120//hepoxilin A3 synthase activity;GO:0051213//dioxygenase activity;GO:0106255//hydroperoxy icosatetraenoate isomerase activity;GO:0106256//hydroperoxy icosatetraenoate dehydratase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006690//icosanoid metabolic process;GO:0019233//sensory perception of pain;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0043651//linoleic acid metabolic process;GO:0045444//fat cell differentiation;GO:0046513//ceramide biosynthetic process;GO:0051122//hepoxilin biosynthetic process;GO:0061436//establishment of skin barrier	--
ENSG00000179151	11.656	13.106	14.884	14.131	15.546	13.153	795.87	857	668.89	646.92	845	650	EDC3	enhancer of mRNA decapping 3 [Source:HGNC Symbol;Acc:HGNC:26114]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12615	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0033962//P-body assembly;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000179152	10.52	8.677	9.405	8.716	8.415	11.045	579	501	359	344	395	464	TCAIM	"T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241]"	-	-	-	-	GO:0005739//mitochondrion	-	-	--
ENSG00000179163	29.451	33.737	34.38	30.775	30.921	28.736	1248	1437	1076	966	1107	886	FUCA1	alpha-L-fucosidase 1 [Source:HGNC Symbol;Acc:HGNC:4006]	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K01206;K01206	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004560//alpha-L-fucosidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0005975//carbohydrate metabolic process;GO:0006004//fucose metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0006629//lipid metabolic process;GO:0008152//metabolic process;GO:0016139//glycoside catabolic process;GO:0019377//glycolipid catabolic process	--
ENSG00000179165	0	0	0.031	0	0	0	0	0	1	0	0	0	PXT1	peroxisomal testis enriched protein 1 [Source:HGNC Symbol;Acc:HGNC:18312]	-	-	-	-	GO:0005634//nucleus;GO:0005777//peroxisome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0043065//positive regulation of apoptotic process	--
ENSG00000179168	1.19	0.833	1.347	1.738	1.66	1.596	35	39	39	43	50	33	GGN	gametogenetin [Source:HGNC Symbol;Acc:HGNC:18869]	-	-	-	-	-	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0006302//double-strand break repair;GO:0007276//gamete generation;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000179172	0	0	0	0	0	0	0	0	0	0	0	0	HNRNPCL1	heterogeneous nuclear ribonucleoprotein C like 1 [Source:HGNC Symbol;Acc:HGNC:29295]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000179178	1.746	2.333	1.8	2.779	3.134	2.042	67	90	51	79	82	57	TMEM125	transmembrane protein 125 [Source:HGNC Symbol;Acc:HGNC:28275]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000179195	74.496	66.615	62.368	46.365	50.592	57.033	6682.91	5995	4132	3070	3831	3710	ZNF664	zinc finger protein 664 [Source:HGNC Symbol;Acc:HGNC:25406]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000179213	0	0	0	0	0	0	0	0	0	0	0	0	SIGLECL1	SIGLEC family like 1 [Source:HGNC Symbol;Acc:HGNC:26856]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000179218	668.242	727.898	660.581	746.183	717.002	642.557	25143	27483	18526	21056	22840	17702	CALR	calreticulin [Source:HGNC Symbol;Acc:HGNC:1455]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems	"Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Folding, sorting and degradation;Infectious disease: parasitic;Immune system"	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko04141//Protein processing in endoplasmic reticulum;ko05142//Chagas disease;ko04612//Antigen processing and presentation	K08057;K08057;K08057;K08057;K08057;K08057;K08057;K08057;K08057	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005844//polysome;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0033018//sarcoplasmic reticulum lumen;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042824//MHC class I peptide loading complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044194//cytolytic granule;GO:0044322//endoplasmic reticulum quality control compartment;GO:0048471//perinuclear region of cytoplasm;GO:0060473//cortical granule;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0071682//endocytic vesicle lumen	GO:0001849//complement component C1q complex binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005178//integrin binding;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030246//carbohydrate binding;GO:0031625//ubiquitin protein ligase binding;GO:0042277//peptide binding;GO:0042562//hormone binding;GO:0044183//protein folding chaperone;GO:0046872//metal ion binding;GO:0050681//androgen receptor binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0006355//regulation of transcription, DNA-templated;GO:0006457//protein folding;GO:0006611//protein export from nucleus;GO:0006874//cellular calcium ion homeostasis;GO:0007283//spermatogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0017148//negative regulation of translation;GO:0022417//protein maturation by protein folding;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0032355//response to estradiol;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0033574//response to testosterone;GO:0034504//protein localization to nucleus;GO:0034975//protein folding in endoplasmic reticulum;GO:0040020//regulation of meiotic nuclear division;GO:0042921//glucocorticoid receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0045665//negative regulation of neuron differentiation;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0050766//positive regulation of phagocytosis;GO:0050821//protein stabilization;GO:0051208//sequestering of calcium ion;GO:0055007//cardiac muscle cell differentiation;GO:0071285//cellular response to lithium ion;GO:0071310//cellular response to organic substance;GO:0090398//cellular senescence;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901164//negative regulation of trophoblast cell migration;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2000510//positive regulation of dendritic cell chemotaxis"	--
ENSG00000179222	286.17	299.491	301.387	318.106	319.779	287.909	16138	16984	12560	13286	15240	11815	MAGED1	MAGE family member D1 [Source:HGNC Symbol;Acc:HGNC:6813]	Organismal Systems	Nervous system	ko04722//Neurotrophin signaling pathway	K12464	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0042981//regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:1900181//negative regulation of protein localization to nucleus;GO:2001235//positive regulation of apoptotic signaling pathway"	--
ENSG00000179240	1.041	1.118	1.269	0.909	1.031	1.223	131	130.01	81	94	118	86	GVQW3	GVQW motif containing 3 [Source:HGNC Symbol;Acc:HGNC:51239]	-	-	-	-	-	-	-	--
ENSG00000179241	3.215	2.377	2.242	2.935	2.409	2.832	227	186	131	172	161	163	LDLRAD3	low density lipoprotein receptor class A domain containing 3 [Source:HGNC Symbol;Acc:HGNC:27046]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	GO:0006898//receptor-mediated endocytosis;GO:0070613//regulation of protein processing	--
ENSG00000179242	0.101	0.19	0.029	0.285	0.221	0.3	14	16	3	25	13	15	CDH4	cadherin 4 [Source:HGNC Symbol;Acc:HGNC:1763]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06797	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex	GO:0005509//calcium ion binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007411//axon guidance;GO:0045773//positive regulation of axon extension;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000179256	0.046	0.16	0.124	0.371	0.271	0.189	2	7	4	12	10	6	SMCO3	single-pass membrane protein with coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:34401]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000179262	48.079	47.004	50.725	59.717	53.798	55.866	1749.3	1716.25	1361.79	1607.74	1652.03	1479.6	RAD23A	"RAD23 homolog A, nucleotide excision repair protein [Source:HGNC Symbol;Acc:HGNC:9812]"	Genetic Information Processing;Genetic Information Processing	"Folding, sorting and degradation;Replication and repair"	ko04141//Protein processing in endoplasmic reticulum;ko03420//Nucleotide excision repair	K10839;K10839	GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0070628//proteasome binding;GO:1990381//ubiquitin-specific protease binding	GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031648//protein destabilization;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045070//positive regulation of viral genome replication;GO:0045787//positive regulation of cell cycle	--
ENSG00000179270	2.377	2.266	2.109	2.014	2.032	2.486	360	345	236	226	260	274	PCARE	photoreceptor cilium actin regulator [Source:HGNC Symbol;Acc:HGNC:34383]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005929//cilium;GO:0042995//cell projection	-	GO:0007601//visual perception;GO:0035845//photoreceptor cell outer segment organization;GO:0050896//response to stimulus;GO:1903546//protein localization to photoreceptor outer segment	--
ENSG00000179271	18.17	17.265	17.167	22.711	18.031	19.417	666.7	636.75	465.21	617.26	558.97	518.4	GADD45GIP1	GADD45G interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29996]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0032543//mitochondrial translation	--
ENSG00000179284	1.384	1.241	1.283	1.465	0.769	1.265	51	46	35	40	24	34	DAND5	DAN domain BMP antagonist family member 5 [Source:HGNC Symbol;Acc:HGNC:26780]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0016015//morphogen activity	GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0007368//determination of left/right symmetry;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0035582//sequestering of BMP in extracellular matrix;GO:0038101//sequestering of nodal from receptor via nodal binding;GO:0061371//determination of heart left/right asymmetry;GO:1900108//negative regulation of nodal signaling pathway;GO:1900176//negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	--
ENSG00000179292	39.207	34.018	37.603	71.267	65.227	64.015	2064	1800	1462	2779	2901	2452	TMEM151A	transmembrane protein 151A [Source:HGNC Symbol;Acc:HGNC:28497]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000179295	31.465	27.476	27.845	22.863	24.274	25.75	3626	3190	2395	1890	2275	2083	PTPN11	protein tyrosine phosphatase non-receptor type 11 [Source:HGNC Symbol;Acc:HGNC:9644]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Signal transduction;Cancer: overview;Signal transduction;Cancer: overview;Immune system;Development and regeneration;Signal transduction;Nervous system;Immune system;Endocrine and metabolic disease;Immune system;Cancer: overview;Cancer: specific types;Cancer: specific types;Infectious disease: bacterial;Endocrine system	ko05168//Herpes simplex virus 1 infection;ko05130//Pathogenic Escherichia coli infection;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04072//Phospholipase D signaling pathway;ko05205//Proteoglycans in cancer;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04630//JAK-STAT signaling pathway;ko04722//Neurotrophin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04931//Insulin resistance;ko04625//C-type lectin receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05220//Chronic myeloid leukemia;ko05211//Renal cell carcinoma;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway	K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293;K07293	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0001784//phosphotyrosine residue binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0051428//peptide hormone receptor binding;GO:1990782//protein tyrosine kinase binding	GO:0000077//DNA damage checkpoint signaling;GO:0006470//protein dephosphorylation;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0007409//axonogenesis;GO:0007420//brain development;GO:0007507//heart development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0016311//dephosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0021697//cerebellar cortex formation;GO:0030220//platelet formation;GO:0031295//T cell costimulation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0032528//microvillus organization;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033277//abortive mitotic cell cycle;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035855//megakaryocyte development;GO:0036302//atrioventricular canal development;GO:0038127//ERBB signaling pathway;GO:0042445//hormone metabolic process;GO:0042593//glucose homeostasis;GO:0043254//regulation of protein-containing complex assembly;GO:0043408//regulation of MAPK cascade;GO:0045778//positive regulation of ossification;GO:0045931//positive regulation of mitotic cell cycle;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0046825//regulation of protein export from nucleus;GO:0046887//positive regulation of hormone secretion;GO:0046888//negative regulation of hormone secretion;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048609//multicellular organismal reproductive process;GO:0048806//genitalia development;GO:0048839//inner ear development;GO:0048873//homeostasis of number of cells within a tissue;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051463//negative regulation of cortisol secretion;GO:0060020//Bergmann glial cell differentiation;GO:0060125//negative regulation of growth hormone secretion;GO:0060325//face morphogenesis;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0061582//intestinal epithelial cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071364//cellular response to epidermal growth factor stimulus	--
ENSG00000179299	3.088	1.736	2.129	1.395	2.281	2.908	242.51	147.34	133.25	83.54	146.41	173.93	NSUN7	NOP2/Sun RNA methyltransferase family member 7 [Source:HGNC Symbol;Acc:HGNC:25857]	-	-	-	-	-	GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000179300	0	0	0	0	0	0	0	0	0	0	0	0	RTL3	retrotransposon Gag like 3 [Source:HGNC Symbol;Acc:HGNC:22997]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000179304	3.373	2.628	5.253	3.964	2.187	4.231	205.28	166.43	187.41	141.14	50.55	131.26	FAM156B	family with sequence similarity 156 member B [Source:HGNC Symbol;Acc:HGNC:31962]	-	-	-	-	GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0035064//methylated histone binding	-	--
ENSG00000179314	14.196	14.898	14.487	12.591	12.394	13.403	1490.86	1523.72	1098	1045	1128	1055	WSCD1	WSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29060]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity	GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000179331	0	0	0	0.104	0	0.035	0	0	0	3	0	1	RAB39A	"RAB39A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16521]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006914//autophagy;GO:0015031//protein transport;GO:0032482//Rab protein signal transduction;GO:0090383//phagosome acidification;GO:0090385//phagosome-lysosome fusion	--
ENSG00000179335	14.563	15.446	16.878	14.601	15.533	18.126	575.13	584	488.11	444.08	499	454	CLK3	CDC like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2071]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031410//cytoplasmic vesicle;GO:0045111//intermediate filament cytoskeleton	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043484//regulation of RNA splicing;GO:0046777//protein autophosphorylation	--
ENSG00000179344	3.328	2.626	2.691	2.644	1.744	3.41	118	92	71	70	53	81	HLA-DQB1	"major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042613//MHC class II protein complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation	--
ENSG00000179348	0.272	0.156	0.241	0.103	0.35	0.214	11	10	3	5	9	7	GATA2	GATA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4171]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001223//transcription coactivator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070742//C2H2 zinc finger domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001655//urogenital system development;GO:0001709//cell fate determination;GO:0001764//neuron migration;GO:0001892//embryonic placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006909//phagocytosis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010725//regulation of primitive erythrocyte differentiation;GO:0021514//ventral spinal cord interneuron differentiation;GO:0021533//cell differentiation in hindbrain;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0021954//central nervous system neuron development;GO:0021983//pituitary gland development;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0033993//response to lipid;GO:0035019//somatic stem cell population maintenance;GO:0035065//regulation of histone acetylation;GO:0035854//eosinophil fate commitment;GO:0042472//inner ear morphogenesis;GO:0043306//positive regulation of mast cell degranulation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0045165//cell fate commitment;GO:0045599//negative regulation of fat cell differentiation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048663//neuron fate commitment;GO:0048873//homeostasis of number of cells within a tissue;GO:0050766//positive regulation of phagocytosis;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0060216//definitive hemopoiesis;GO:0060872//semicircular canal development;GO:0061042//vascular wound healing;GO:0070345//negative regulation of fat cell proliferation;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090102//cochlea development;GO:0097154//GABAergic neuron differentiation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:2000178//negative regulation of neural precursor cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000977//regulation of forebrain neuron differentiation"	zf-GATA
ENSG00000179361	1.448	1.441	1.436	1.031	1.2	1.003	127	127	93	67	89	64	ARID3B	AT-rich interaction domain 3B [Source:HGNC Symbol;Acc:HGNC:14350]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0045944//positive regulation of transcription by RNA polymerase II	ARID
ENSG00000179363	0	0.262	0.178	0	0.078	0	0	4	2	0	1	0	TMEM31	transmembrane protein 31 [Source:HGNC Symbol;Acc:HGNC:28601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000179364	18.783	18.902	18.389	21.149	20.389	19.263	1571.04	1570.67	1103.11	1289.42	1435.56	1142.29	PACS2	phosphofurin acidic cluster sorting protein 2 [Source:HGNC Symbol;Acc:HGNC:23794]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0000045//autophagosome assembly;GO:0006915//apoptotic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0034497//protein localization to phagophore assembly site;GO:0072659//protein localization to plasma membrane;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000179387	22.931	20.119	17.205	12.441	12.977	12.29	1756	1393	994	705	825	733	ELMOD2	ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111]	-	-	-	-	GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0043547//positive regulation of GTPase activity;GO:0050688//regulation of defense response to virus;GO:0051607//defense response to virus	--
ENSG00000179388	0.011	0.043	0	0	0.126	0	1	4	0	0	5	0	EGR3	early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240]	Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Infectious disease: viral;Immune system	ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04625//C-type lectin receptor signaling pathway	K12497;K12497;K12497	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045202//synapse	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007274//neuromuscular synaptic transmission;GO:0007422//peripheral nervous system development;GO:0007517//muscle organ development;GO:0007623//circadian rhythm;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0035767//endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000179397	0.152	0.099	0.172	0.095	0.177	0.185	10	6	8	5	9	9	CATSPERE	catsper channel auxiliary subunit epsilon [Source:HGNC Symbol;Acc:HGNC:28491]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	-	-	--
ENSG00000179399	0.1	0.016	0.068	0	0.078	0	2	1	1	0	4	0	GPC5	glypican 5 [Source:HGNC Symbol;Acc:HGNC:4453]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	GO:0001523//retinoid metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006027//glycosaminoglycan catabolic process;GO:0009966//regulation of signal transduction;GO:0016477//cell migration;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1905475//regulation of protein localization to membrane	--
ENSG00000179403	1.725	1.513	1.523	1.37	1.805	0.808	93	90	66	65	83	27	VWA1	von Willebrand factor A domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30910]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005614//interstitial matrix;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0030198//extracellular matrix organization;GO:0048266//behavioral response to pain	--
ENSG00000179407	0	0	0	0	0	0	0	0	0	0	0	0	DNAJB8	DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0061077//chaperone-mediated protein folding;GO:0090084//negative regulation of inclusion body assembly	--
ENSG00000179409	10.586	9.494	10.597	10.787	11.238	12.51	707	628	453	523	588	481	GEMIN4	gem nuclear organelle associated protein 4 [Source:HGNC Symbol;Acc:HGNC:15717]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0070062//extracellular exosome;GO:0097504//Gemini of coiled bodies	GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	GO:0000387//spliceosomal snRNP assembly;GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000179412	0	0	0	0	0	0	0	0	0	0	0	0	HNRNPCL4	heterogeneous nuclear ribonucleoprotein C like 4 [Source:HGNC Symbol;Acc:HGNC:51333]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12884	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000179431	0.721	0.658	0.434	0.92	0.949	0.523	36	33	16	34	40	19	FJX1	four-jointed box kinase 1 [Source:HGNC Symbol;Acc:HGNC:17166]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	GO:0007267//cell-cell signaling;GO:0010842//retina layer formation	--
ENSG00000179454	5.412	4.135	5.282	3.298	4.25	3.855	638	483	384	284	356	361	KLHL28	kelch like family member 28 [Source:HGNC Symbol;Acc:HGNC:19741]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000179455	0.3	0.256	0.171	0.134	0.254	0.293	12	8	5	4	10	7	MKRN3	makorin ring finger protein 3 [Source:HGNC Symbol;Acc:HGNC:7114]	-	-	-	-	GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination	--
ENSG00000179456	19.686	17.928	18.396	13.537	15.287	17.975	1266	1124	807	599	849	802	ZBTB18	zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:13030]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	ZBTB
ENSG00000179468	0	0	0	0	0	0	0	0	0	0	0	0	OR9A2	olfactory receptor family 9 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:15093]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179476	1.18	1.258	1.023	1.015	1.502	1.242	64	77	46	39	73	55	C14orf28	chromosome 14 open reading frame 28 [Source:HGNC Symbol;Acc:HGNC:19834]	-	-	-	-	-	-	-	--
ENSG00000179477	0.039	0	0	0	0	0	1	0	0	0	0	0	ALOX12B	"arachidonate 12-lipoxygenase, 12R type [Source:HGNC Symbol;Acc:HGNC:430]"	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Nervous system;Lipid metabolism	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko00590//Arachidonic acid metabolism	K08021;K08021;K08021	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	"GO:0003824//catalytic activity;GO:0004052//arachidonate 12(S)-lipoxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016829//lyase activity;GO:0016853//isomerase activity;GO:0046872//metal ion binding;GO:0047677//arachidonate 8(R)-lipoxygenase activity;GO:0051213//dioxygenase activity;GO:0106237//arachidonate 12(R)-lipoxygenase activity;GO:1990136//linoleate 9S-lipoxygenase activity"	GO:0006497//protein lipidation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006690//icosanoid metabolic process;GO:0010628//positive regulation of gene expression;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0032787//monocarboxylic acid metabolic process;GO:0034440//lipid oxidation;GO:0043410//positive regulation of MAPK cascade;GO:0043651//linoleic acid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0051122//hepoxilin biosynthetic process;GO:0061436//establishment of skin barrier;GO:0070257//positive regulation of mucus secretion	--
ENSG00000179520	0.097	0.241	0.082	0.065	0.158	0.183	8	20	5	4	11	11	SLC17A8	solute carrier family 17 member 8 [Source:HGNC Symbol;Acc:HGNC:20151]	Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Nervous system;Nervous system;Nervous system;Substance dependence	ko04723//Retrograde endocannabinoid signaling;ko04724//Glutamatergic synapse;ko04721//Synaptic vesicle cycle;ko05033//Nicotine addiction	K12302;K12302;K12302;K12302	GO:0005737//cytoplasm;GO:0005771//multivesicular body;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030425//dendrite;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0097440//apical dendrite;GO:0097441//basal dendrite;GO:0097451//glial limiting end-foot;GO:1990030//pericellular basket	GO:0005313//L-glutamate transmembrane transporter activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005515//protein binding;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	"GO:0003407//neural retina development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0006836//neurotransmitter transport;GO:0007420//brain development;GO:0007605//sensory perception of sound;GO:0015813//L-glutamate transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0050803//regulation of synapse structure or activity;GO:0055085//transmembrane transport;GO:0090102//cochlea development;GO:0098700//neurotransmitter loading into synaptic vesicle"	--
ENSG00000179526	22.175	23.349	29.344	29.972	26.449	25.04	652	681	618	643	650	537	SHARPIN	SHANK associated RH domain interactor [Source:HGNC Symbol;Acc:HGNC:25321]	Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Immune system;Cell growth and death	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis	K20894;K20894;K20894	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0071797//LUBAC complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0007005//mitochondrion organization;GO:0007420//brain development;GO:0008544//epidermis development;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0030262//apoptotic nuclear changes;GO:0031424//keratinization;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050728//negative regulation of inflammatory response;GO:0097039//protein linear polyubiquitination;GO:2000348//regulation of CD40 signaling pathway	--
ENSG00000179528	0.879	0.766	0.642	0.971	1.117	0.865	20	18	10	17	21	14	LBX2	ladybird homeobox 2 [Source:HGNC Symbol;Acc:HGNC:15525]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0042692//muscle cell differentiation;GO:1904105//positive regulation of convergent extension involved in gastrulation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway	Homeobox
ENSG00000179532	0.464	0.46	0.624	0.524	1.318	0.931	87	68	46	88	89	71	DNHD1	dynein heavy chain domain 1 [Source:HGNC Symbol;Acc:HGNC:26532]	-	-	-	-	GO:0030286//dynein complex;GO:0036156//inner dynein arm;GO:0070062//extracellular exosome	GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0007018//microtubule-based movement	--
ENSG00000179542	0.507	0.295	0.1	0.171	0.266	0.306	53	41	7	17	24	22	SLITRK4	SLIT and NTRK like family member 4 [Source:HGNC Symbol;Acc:HGNC:23502]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	GO:0005515//protein binding	GO:0007409//axonogenesis;GO:0050807//regulation of synapse organization;GO:0051965//positive regulation of synapse assembly;GO:1905606//regulation of presynapse assembly	--
ENSG00000179546	0.073	0.058	0.177	0	0	0	5	4	9	0	0	0	HTR1D	5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04726//Serotonergic synapse;ko04742//Taste transduction	K04153;K04153;K04153;K04153	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0051378//serotonin binding	"GO:0006939//smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0014827//intestine smooth muscle contraction;GO:0040012//regulation of locomotion;GO:0042310//vasoconstriction;GO:0050795//regulation of behavior"	--
ENSG00000179562	7.463	7.134	7.559	6.89	6.373	8.315	639	614	478	437	461	518	GCC1	GRIP and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19095]	-	-	-	-	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding	-	--
ENSG00000179564	0	0	0	0	0	0	0	0	0	0	0	0	LSMEM2	leucine rich single-pass membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:26781]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000179580	0	0	0	0	0	0	0	0	0	0	0	0	RNF151	ring finger protein 151 [Source:HGNC Symbol;Acc:HGNC:23235]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation	--
ENSG00000179583	0.668	0.372	0.93	0.478	0.23	0.418	136.5	97.99	101.42	79.09	60.85	50.64	CIITA	class II major histocompatibility complex transactivator [Source:HGNC Symbol;Acc:HGNC:7067]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Infectious disease: viral;Immune disease;Infectious disease: parasitic;Immune system	ko05152//Tuberculosis;ko05164//Influenza A;ko05340//Primary immunodeficiency;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation	K08060;K08060;K08060;K08060;K08060	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016605//PML body	GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003713//transcription coactivator activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008022//protein C-terminus binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0044877//protein-containing complex binding;GO:0106310//protein serine kinase activity;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007568//aging;GO:0016310//phosphorylation;GO:0032966//negative regulation of collagen biosynthetic process;GO:0034341//response to interferon-gamma;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046597//negative regulation of viral entry into host cell;GO:0046677//response to antibiotic;GO:0071257//cellular response to electrical stimulus;GO:0071346//cellular response to interferon-gamma;GO:0071360//cellular response to exogenous dsRNA"	--
ENSG00000179588	3.08	3.02	3.641	4.505	4.825	4.696	347	342	285	376	450	385	ZFPM1	"zinc finger protein, FOG family member 1 [Source:HGNC Symbol;Acc:HGNC:19762]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002295//T-helper cell lineage commitment;GO:0003151//outflow tract morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0003192//mitral valve formation;GO:0003195//tricuspid valve formation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0030220//platelet formation;GO:0030851//granulocyte differentiation;GO:0032091//negative regulation of protein binding;GO:0032642//regulation of chemokine production;GO:0032713//negative regulation of interleukin-4 production;GO:0032729//positive regulation of interferon-gamma production;GO:0035162//embryonic hemopoiesis;GO:0035855//megakaryocyte development;GO:0045599//negative regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048872//homeostasis of number of cells;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060318//definitive erythrocyte differentiation;GO:0060319//primitive erythrocyte differentiation;GO:0060377//negative regulation of mast cell differentiation;GO:0060412//ventricular septum morphogenesis;GO:0060413//atrial septum morphogenesis	zf-C2H2
ENSG00000179593	0	0	0	0	0	0	0	0	0	0	0	0	ALOX15B	arachidonate 15-lipoxygenase type B [Source:HGNC Symbol;Acc:HGNC:434]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Nervous system;Lipid metabolism	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko00590//Arachidonic acid metabolism	K08022;K08022;K08022	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0070062//extracellular exosome	"GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016165//linoleate 13S-lipoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0036403//arachidonate 8(S)-lipoxygenase activity;GO:0046872//metal ion binding;GO:0050473//arachidonate 15-lipoxygenase activity;GO:0051213//dioxygenase activity;GO:1990136//linoleate 9S-lipoxygenase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0030336//negative regulation of cell migration;GO:0030850//prostate gland development;GO:0030856//regulation of epithelial cell differentiation;GO:0032722//positive regulation of chemokine production;GO:0034440//lipid oxidation;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0043651//linoleic acid metabolic process;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045786//negative regulation of cell cycle;GO:0045926//negative regulation of growth;GO:0051122//hepoxilin biosynthetic process;GO:0071926//endocannabinoid signaling pathway;GO:1901696//cannabinoid biosynthetic process;GO:2001303//lipoxin A4 biosynthetic process	--
ENSG00000179598	1.753	1.512	1.691	1.313	1.339	1.562	93.73	81.27	66.78	52	60.47	60.76	PLD6	phospholipase D family member 6 [Source:HGNC Symbol;Acc:HGNC:30447]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0035755//cardiolipin hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	"GO:0006629//lipid metabolic process;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008053//mitochondrial fusion;GO:0010636//positive regulation of mitochondrial fusion;GO:0016042//lipid catabolic process;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0051321//meiotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000179600	0	0	0	0	0	0	0	0	0	0	0	0	GPHB5	glycoprotein hormone subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:18055]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway	K25484;K25484	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0031531//thyrotropin-releasing hormone receptor binding;GO:0046982//protein heterodimerization activity	GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000179603	1.945	2.302	1.966	1.658	2.173	1.505	130	180	106	95	131	85	GRM8	glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse	K04610;K04610;K04610	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0001642//group III metabotropic glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008066//glutamate receptor activity	"GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007601//visual perception;GO:0023052//signaling;GO:0050896//response to stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic"	--
ENSG00000179604	46.626	45.043	41.943	37.695	39.023	36.023	2749	2748	1917	1616	1918	1540	CDC42EP4	CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0045335//phagocytic vesicle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly;GO:0071346//cellular response to interferon-gamma	--
ENSG00000179615	0	0	0	0	0	0	0	0	0	0	0	0	OR2AP1	olfactory receptor family 2 subfamily AP member 1 [Source:HGNC Symbol;Acc:HGNC:15335]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179626	0	0	0	0	0	0	0	0	0	0	0	0	OR6C4	olfactory receptor family 6 subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:19632]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179627	1.659	2.233	2.933	1.46	1.8	1.65	106	157	121	81	100	86	ZBTB42	zinc finger and BTB domain containing 42 [Source:HGNC Symbol;Acc:HGNC:32550]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development	ZBTB
ENSG00000179630	0.447	0.345	0.47	0.61	0.615	1.056	29	29	25	30	44	42	LACC1	laccase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26789]	Metabolism;Metabolism	Nucleotide metabolism;Amino acid metabolism	ko00230//Purine metabolism;ko00270//Cysteine and methionine metabolism	K05810;K05810	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005783//endoplasmic reticulum	GO:0004000//adenosine deaminase activity;GO:0004731//purine-nucleoside phosphorylase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0017061//S-methyl-5-thioadenosine phosphorylase activity;GO:0046872//metal ion binding;GO:0047975//guanosine phosphorylase activity	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0006954//inflammatory response;GO:0030641//regulation of cellular pH;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:1900542//regulation of purine nucleotide metabolic process	--
ENSG00000179632	45.39	45.883	48.712	58.549	52.523	51.306	1546	1600	1253	1481	1540	1284	MAF1	"MAF1 homolog, negative regulator of RNA polymerase III [Source:HGNC Symbol;Acc:HGNC:24966]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000994//RNA polymerase III core binding;GO:0001002//RNA polymerase III type 1 promoter sequence-specific DNA binding;GO:0001003//RNA polymerase III type 2 promoter sequence-specific DNA binding;GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0005515//protein binding	GO:0016479//negative regulation of transcription by RNA polymerase I;GO:0016480//negative regulation of transcription by RNA polymerase III	Others
ENSG00000179636	0	0	0	0	0	0	0	0	0	0	0	0	TPPP2	tubulin polymerization promoting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19293]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0015631//tubulin binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0032273//positive regulation of protein polymerization;GO:1901317//regulation of flagellated sperm motility	--
ENSG00000179639	0	0	0	0	0	0	0	0	0	0	0	0	FCER1A	Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Immune system;Signal transduction;Immune disease	ko04072//Phospholipase D signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04071//Sphingolipid signaling pathway;ko05310//Asthma	K08089;K08089;K08089;K08089	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019863//IgE binding	GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response	--
ENSG00000179673	0.176	0.218	0.238	0.415	0.416	0.181	4	5	4	7	8	3	RPRML	reprimo like [Source:HGNC Symbol;Acc:HGNC:32422]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000179674	0.037	0.037	0	0.202	0.044	0	1	1	0	4	1	0	ARL14	ADP ribosylation factor like GTPase 14 [Source:HGNC Symbol;Acc:HGNC:22974]	-	-	-	-	GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000179695	0	0	0	0	0	0	0	0	0	0	0	0	OR6C2	olfactory receptor family 6 subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:15436]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179698	0.042	0.027	0.076	0.009	0.008	0.074	6	4	8	1	1	8	WDR97	WD repeat domain 97 [Source:HGNC Symbol;Acc:HGNC:26959]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000179709	0	0	0	0	0	0	0	0	0	0	0	0	NLRP8	NLR family pyrin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:22940]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000179715	0.052	0.052	0.089	0	0.102	0.071	2	2	1	0	2	2	PCED1B	PC-esterase domain containing 1B [Source:HGNC Symbol;Acc:HGNC:28255]	-	-	-	-	-	GO:0005515//protein binding;GO:0016740//transferase activity	-	--
ENSG00000179750	0.334	0.444	0.082	0.051	0.323	0.458	11	15	2	1	9	11	APOBEC3B	apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016554//cytidine to uridine editing;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000179751	0	0	0	0	0	0	0	0	0	0	0	0	SYCN	syncollin [Source:HGNC Symbol;Acc:HGNC:18442]	-	-	-	-	GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle	-	GO:0006887//exocytosis	--
ENSG00000179761	0.022	0.347	0.091	0.3	0.302	0.122	1	12	1	10	11	4	PIPOX	pipecolic acid and sarcosine oxidase [Source:HGNC Symbol;Acc:HGNC:17804]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko00310//Lysine degradation;ko00260//Glycine, serine and threonine metabolism"	K00306;K00306;K00306;K00306	GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008115//sarcosine oxidase activity;GO:0016491//oxidoreductase activity;GO:0050031//L-pipecolate oxidase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0006554//lysine catabolic process;GO:0033514//L-lysine catabolic process to acetyl-CoA via L-pipecolate	--
ENSG00000179772	1.666	1.253	0.902	1.1	1.183	1.985	45	34	18	22	27	39	FOXS1	forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001568//blood vessel development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050885//neuromuscular process controlling balance"	Fork_head
ENSG00000179774	0.032	0	0.043	0.086	0	0	1	0	1	2	0	0	ATOH7	atonal bHLH transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:13907]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0030424//axon;GO:0043204//perikaryon	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0003407//neural retina development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007623//circadian rhythm;GO:0009649//entrainment of circadian clock;GO:0010996//response to auditory stimulus;GO:0021554//optic nerve development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0043153//entrainment of circadian clock by photoperiod;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902336//positive regulation of retinal ganglion cell axon guidance"	bHLH
ENSG00000179776	0	0	0.061	0	0.027	0	0	0	2	0	1	0	CDH5	cadherin 5 [Source:HGNC Symbol;Acc:HGNC:1764]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Cardiovascular disease;Immune system	ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04670//Leukocyte transendothelial migration	K06533;K06533;K06533	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016342//catenin complex;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0071944//cell periphery	GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019903//protein phosphatase binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0070051//fibrinogen binding;GO:0070700//BMP receptor binding;GO:1990782//protein tyrosine kinase binding	GO:0000902//cell morphogenesis;GO:0001932//regulation of protein phosphorylation;GO:0001944//vasculature development;GO:0001955//blood vessel maturation;GO:0006874//cellular calcium ion homeostasis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030335//positive regulation of cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0031115//negative regulation of microtubule polymerization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0034332//adherens junction organization;GO:0035307//positive regulation of protein dephosphorylation;GO:0035633//maintenance of blood-brain barrier;GO:0043114//regulation of vascular permeability;GO:0043534//blood vessel endothelial cell migration;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0045766//positive regulation of angiogenesis;GO:0050728//negative regulation of inflammatory response;GO:0070830//bicellular tight junction assembly;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1902396//protein localization to bicellular tight junction;GO:1903142//positive regulation of establishment of endothelial barrier;GO:2000114//regulation of establishment of cell polarity;GO:2000352//negative regulation of endothelial cell apoptotic process	--
ENSG00000179796	0.031	0	0.019	0	0	0	1	0	2	0	0	0	LRRC3B	leucine rich repeat containing 3B [Source:HGNC Symbol;Acc:HGNC:28105]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000179813	0.527	0.732	0.358	0.414	0.227	0.02	36	50	18	21	13	1	FAM216B	family with sequence similarity 216 member B [Source:HGNC Symbol;Acc:HGNC:26883]	-	-	-	-	-	-	-	--
ENSG00000179817	0	0	0	0	0	0	0	0	0	0	0	0	MRGPRX4	MAS related GPR family member X4 [Source:HGNC Symbol;Acc:HGNC:17617]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000179820	45.517	46.233	44.933	40.683	41.59	41.833	1913	1954	1381	1231	1453	1275	MYADM	myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544]	-	-	-	-	GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030864//cortical actin cytoskeleton;GO:0045121//membrane raft	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001933//negative regulation of protein phosphorylation;GO:0010629//negative regulation of gene expression;GO:0030335//positive regulation of cell migration;GO:0030837//negative regulation of actin filament polymerization;GO:0031579//membrane raft organization;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0061028//establishment of endothelial barrier;GO:0072659//protein localization to plasma membrane;GO:0090038//negative regulation of protein kinase C signaling;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading	--
ENSG00000179826	0	0	0	0	0.035	0	0	0	0	0	1	0	MRGPRX3	MAS related GPR family member X3 [Source:HGNC Symbol;Acc:HGNC:17980]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000179832	8.706	9.014	8.62	10.717	10.249	9.873	899	941	642	799	882	746	MROH1	maestro heat like repeat family member 1 [Source:HGNC Symbol;Acc:HGNC:26958]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000179833	7.672	6.492	7.176	6.697	7.641	7.666	883	751	610	571	743	642	SERTAD2	SERTA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30784]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0030308//negative regulation of cell growth;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000179841	0.758	0.706	0.483	0.592	0.737	0.858	102	75	48	59	63	84	AKAP5	A-kinase anchoring protein 5 [Source:HGNC Symbol;Acc:HGNC:375]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0043197//dendritic spine;GO:0045121//membrane raft;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0098837//postsynaptic recycling endosome	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008179//adenylate cyclase binding;GO:0017124//SH3 domain binding;GO:0030346//protein phosphatase 2B binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0035254//glutamate receptor binding;GO:0050811//GABA receptor binding;GO:0051018//protein kinase A binding;GO:0060090//molecular adaptor activity;GO:0097110//scaffold protein binding	GO:0007165//signal transduction;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007268//chemical synaptic transmission;GO:0010738//regulation of protein kinase A signaling;GO:0045762//positive regulation of adenylate cyclase activity;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905751//positive regulation of endosome to plasma membrane protein transport	--
ENSG00000179846	0.052	0.02	0.1	0.036	0.029	0	3	2	3	2	1	0	NKPD1	NTPase KAP family P-loop domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24739]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000179855	0	0.012	0	0	0	0	0	1	0	0	0	0	GIPC3	GIPC PDZ domain containing family member 3 [Source:HGNC Symbol;Acc:HGNC:18183]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000179859	2.163	1.229	3.068	1.058	1.281	1.429	80	73	60	40	64	60	RNF227	ring finger protein 227 [Source:HGNC Symbol;Acc:HGNC:27571]	-	-	-	-	-	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000179862	3.202	1.904	1.644	2.733	2.831	2.731	87	52	33	55	65	54	CITED4	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 [Source:HGNC Symbol;Acc:HGNC:18696]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0043627//response to estrogen;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000179869	0.287	0.232	0.131	0.34	0.182	0.047	39	30	14	18	18	12	ABCA13	ATP binding cassette subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:14638]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05647	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097708//intracellular vesicle	GO:0000166//nucleotide binding;GO:0005319//lipid transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006869//lipid transport;GO:0032376//positive regulation of cholesterol transport;GO:0035627//ceramide transport;GO:0055085//transmembrane transport;GO:1900244//positive regulation of synaptic vesicle endocytosis	--
ENSG00000179873	0	0	0	0	0	0	0	0	0	0	0	0	NLRP11	NLR family pyrin domain containing 11 [Source:HGNC Symbol;Acc:HGNC:22945]	-	-	-	-	-	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"	-	--
ENSG00000179886	2.288	2.019	2.578	2.618	2.941	3.624	256	227	213	217	278	295	TIGD5	tigger transposable element derived 5 [Source:HGNC Symbol;Acc:HGNC:18336]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0003677//DNA binding	GO:0008150//biological_process	--
ENSG00000179889	37.544	37.847	41.97	36.126	40.126	41.483	2922.86	2953.27	2331.68	2043.3	2342.06	2190.92	PDXDC1	pyridoxal dependent decarboxylase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28995]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0016829//lyase activity;GO:0016830//carbon-carbon lyase activity;GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0045296//cadherin binding	GO:0019752//carboxylic acid metabolic process	--
ENSG00000179902	0.257	1.444	0.594	0.311	0.546	0	3	14	4	2	4	0	CFAP276	cilia and flagella associated protein 276 [Source:HGNC Symbol;Acc:HGNC:32331]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0015232//heme transmembrane transporter activity;GO:0020037//heme binding	GO:0097037//heme export	--
ENSG00000179909	3.812	3.458	3.387	2.901	3.489	3.898	452	376.01	300	279	344	301	ZNF154	zinc finger protein 154 [Source:HGNC Symbol;Acc:HGNC:12939]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000179912	10.328	8.632	7.624	7.813	7.191	9.867	828.36	667.47	507	443.27	537.01	605.28	R3HDM2	R3H domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29167]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000179913	0	0	0	0	0	0	0	0	0	0	0	0	B3GNT3	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:13528]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07970;K07970;K07970	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0008194//UDP-glycosyltransferase activity;GO:0008457//beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0030311//poly-N-acetyllactosamine biosynthetic process	--
ENSG00000179914	0.04	0.201	0	0.055	0.096	0.278	1	5	0	1	2	5	ITLN1	intelectin 1 [Source:HGNC Symbol;Acc:HGNC:18259]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031526//brush border membrane;GO:0043235//receptor complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding	GO:0001934//positive regulation of protein phosphorylation;GO:0009624//response to nematode;GO:0046326//positive regulation of glucose import;GO:0070207//protein homotrimerization	--
ENSG00000179915	0.067	0	0	0	0.154	0.019	5	0	0	0	3	1	NRXN1	neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07377	GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0031594//neuromuscular junction;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044295//axonal growth cone;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0060077//inhibitory synapse;GO:0098635//protein complex involved in cell-cell adhesion;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0098984//neuron to neuron synapse;GO:0099056//integral component of presynaptic membrane;GO:0099059//integral component of presynaptic active zone membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0033130//acetylcholine receptor binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050839//cell adhesion molecule binding;GO:0097109//neuroligin family protein binding	"GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007158//neuron cell-cell adhesion;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007612//learning;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010739//positive regulation of protein kinase A signaling;GO:0010976//positive regulation of neuron projection development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0021707//cerebellar granule cell differentiation;GO:0023041//neuronal signal transduction;GO:0030534//adult behavior;GO:0031175//neuron projection development;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035176//social behavior;GO:0035418//protein localization to synapse;GO:0042297//vocal learning;GO:0045184//establishment of protein localization;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0048812//neuron projection morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0051490//negative regulation of filopodium assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060074//synapse maturation;GO:0060134//prepulse inhibition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071277//cellular response to calcium ion;GO:0071625//vocalization behavior;GO:0090125//cell-cell adhesion involved in synapse maturation;GO:0090126//protein-containing complex assembly involved in synapse maturation;GO:0090129//positive regulation of synapse maturation;GO:0097091//synaptic vesicle clustering;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:0097114//NMDA glutamate receptor clustering;GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0097117//guanylate kinase-associated protein clustering;GO:0097118//neuroligin clustering involved in postsynaptic membrane assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0097120//receptor localization to synapse;GO:0098693//regulation of synaptic vesicle cycle;GO:0099150//regulation of postsynaptic specialization assembly;GO:0099151//regulation of postsynaptic density assembly;GO:0099542//trans-synaptic signaling by endocannabinoid;GO:0099558//maintenance of synapse structure;GO:0099560//synaptic membrane adhesion;GO:1900020//positive regulation of protein kinase C activity;GO:1900075//positive regulation of neuromuscular synaptic transmission;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1905520//positive regulation of presynaptic active zone assembly;GO:1905606//regulation of presynapse assembly;GO:2000310//regulation of NMDA receptor activity;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000821//regulation of grooming behavior"	--
ENSG00000179918	22.279	21.396	23.097	21.695	22.862	25.985	1037	1001	794	748	899	880	-	-	-	-	-	-	-	-	-	-
ENSG00000179919	0	0	0	0	0	0	0	0	0	0	0	0	OR10A7	olfactory receptor family 10 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:15329]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000179921	0	0.069	0.134	0	0.085	0.048	0	2	3	0	3	1	GPBAR1	G protein-coupled bile acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:19680]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0038181//bile acid receptor activity;GO:0038182//G protein-coupled bile acid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0038184//cell surface bile acid receptor signaling pathway;GO:1903413//cellular response to bile acid;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000179922	2.354	2.848	2.614	3.058	3.892	2.534	97	118	79	92	135	76	ZNF784	zinc finger protein 784 [Source:HGNC Symbol;Acc:HGNC:33111]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000179930	0.219	0.092	0.179	0	0.235	0.109	12	7	10	0	15	6	ZNF648	zinc finger protein 648 [Source:HGNC Symbol;Acc:HGNC:18190]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000179933	18.081	22.181	20.984	22.004	17.184	21.455	790	870	686	590	615	639	C14orf119	chromosome 14 open reading frame 119 [Source:HGNC Symbol;Acc:HGNC:20270]	-	-	-	-	GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000179934	0	0	0	0	0	0	0	0	0	0	0	0	CCR8	C-C motif chemokine receptor 8 [Source:HGNC Symbol;Acc:HGNC:1609]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Cancer: overview;Infectious disease: viral;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04183;K04183;K04183;K04183;K04183	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000179938	0.012	0	0	0	0.037	0	1.34	0	0	0	3.39	0	GOLGA8J	golgin A8 family member J [Source:HGNC Symbol;Acc:HGNC:38650]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000179941	8.269	6.049	6.824	5.582	5.582	7.614	612	450	373	306	349	410	BBS10	Bardet-Biedl syndrome 10 [Source:HGNC Symbol;Acc:HGNC:26291]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0007601//visual perception;GO:0043254//regulation of protein-containing complex assembly;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0051131//chaperone-mediated protein complex assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000179943	10.386	8.096	11.011	11.402	9.818	10.612	461	440	404	452	428	396	FIZ1	FLT3 interacting zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:25917]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity;GO:0030971//receptor tyrosine kinase binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0001934//positive regulation of protein phosphorylation;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000179950	93.951	100.916	113.039	117.678	110.236	108.713	3150	3492	2879	2907	3141	2690	PUF60	poly(U) binding splicing factor 60 [Source:HGNC Symbol;Acc:HGNC:17042]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12838	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing"	--
ENSG00000179954	3.863	5.008	2.173	3.23	5.903	8.067	365	456	160	247	372	263	SSC5D	scavenger receptor cysteine rich family member with 5 domains [Source:HGNC Symbol;Acc:HGNC:26641]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0001968//fibronectin binding;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0043236//laminin binding;GO:0050840//extracellular matrix binding	GO:0002376//immune system process;GO:0006897//endocytosis;GO:0006952//defense response;GO:0032677//regulation of interleukin-8 production;GO:0032717//negative regulation of interleukin-8 production;GO:0042494//detection of bacterial lipoprotein;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000179958	7.321	8.285	8.401	11.904	11.065	9.706	168	204	152	216	229	173	DCTPP1	dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00240//Pyrimidine metabolism	K16904;K16904	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0032556//pyrimidine deoxyribonucleotide binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0047840//dCTP diphosphatase activity	GO:0006253//dCTP catabolic process;GO:0009143//nucleoside triphosphate catabolic process;GO:0042262//DNA protection	--
ENSG00000179965	4.909	5.227	4.758	6.46	5.651	6.682	153	180	124	165	161	169	ZNF771	zinc finger protein 771 [Source:HGNC Symbol;Acc:HGNC:29653]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000179981	5.006	4.588	4	3.865	4.673	4.134	539	503	323	321	434	334	TSHZ1	teashirt zinc finger homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10669]	Environmental Information Processing	Signal transduction	ko04391//Hippo signaling pathway - fly	K09236	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0010468//regulation of gene expression;GO:0042474//middle ear morphogenesis;GO:0060023//soft palate development	zf-C2H2
ENSG00000179988	1.308	1.281	1.321	1.474	2.254	1.22	31	31	22	27	46	21	PSTK	phosphoseryl-tRNA kinase [Source:HGNC Symbol;Acc:HGNC:28578]	Genetic Information Processing;Metabolism	Translation;Metabolism of other amino acids	ko00970//Aminoacyl-tRNA biosynthesis;ko00450//Selenocompound metabolism	K10837;K10837	-	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0043915//L-seryl-tRNA(Sec) kinase activity	GO:0001514//selenocysteine incorporation;GO:0006412//translation;GO:0016310//phosphorylation;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process	--
ENSG00000180008	3.482	2.167	2.518	2.097	2.573	2.847	492	308	264	219	309	293	SOCS4	suppressor of cytokine signaling 4 [Source:HGNC Symbol;Acc:HGNC:19392]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Endocrine system;Endocrine system;Endocrine and metabolic disease	ko04630//JAK-STAT signaling pathway;ko04910//Insulin signaling pathway;ko04917//Prolactin signaling pathway;ko04930//Type II diabetes mellitus	K04697;K04697;K04697;K04697	GO:0005942//phosphatidylinositol 3-kinase complex	GO:0005515//protein binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000180011	8.462	7.732	9.114	7.465	9.183	8.948	605	630	449	439	578	467	ZADH2	zinc binding alcohol dehydrogenase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28697]	-	-	-	-	GO:0005777//peroxisome	GO:0003674//molecular_function;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0036132//13-prostaglandin reductase activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0008150//biological_process;GO:0045599//negative regulation of fat cell differentiation	--
ENSG00000180016	0	0	0	0	0	0	0	0	0	0	0	0	OR1E1	olfactory receptor family 1 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:8189]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180035	6.021	5.63	5.889	6.548	5.745	8.028	382	359	277	310	297	370	ZNF48	zinc finger protein 48 [Source:HGNC Symbol;Acc:HGNC:13114]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000180042	0	0	0	0	0	0	0	0	0	0	0	0	OR1R1P	olfactory receptor family 1 subfamily R member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:8226]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180043	0	0	0	0	0	0	0	0	0	0	0	0	FAM71E2	family with sequence similarity 71 member E2 [Source:HGNC Symbol;Acc:HGNC:25278]	-	-	-	-	-	-	-	--
ENSG00000180044	0	0.017	0	0	0	0	0	1	0	0	0	0	C3orf80	chromosome 3 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:40048]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000180053	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-6	NK2 homeobox 6 [Source:HGNC Symbol;Acc:HGNC:32940]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0021854//hypothalamus development;GO:0030154//cell differentiation;GO:0035050//embryonic heart tube development;GO:0043066//negative regulation of apoptotic process;GO:0043586//tongue development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:0055014//atrial cardiac muscle cell development;GO:0055015//ventricular cardiac muscle cell development;GO:0060037//pharyngeal system development;GO:0060039//pericardium development"	Homeobox
ENSG00000180061	0	0	0	0	0	0	0	0	0	0	0	0	TMEM150B	transmembrane protein 150B [Source:HGNC Symbol;Acc:HGNC:34415]	-	-	-	-	GO:0000421//autophagosome membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0110165//cellular anatomical entity	-	GO:0006914//autophagy	--
ENSG00000180071	0.568	0.522	0.403	0.588	0.354	0.768	45	41.6	24.5	34	24.64	46	ANKRD18A	ankyrin repeat domain 18A [Source:HGNC Symbol;Acc:HGNC:23643]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000180083	0	0	0	0	0	0	0	0	0	0	0	0	WFDC11	WAP four-disulfide core domain 11 [Source:HGNC Symbol;Acc:HGNC:20478]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity	GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000180089	0.348	0.192	0.838	0.47	0.412	0.532	9	5	16	9	9	10	TMEM86B	transmembrane protein 86B [Source:HGNC Symbol;Acc:HGNC:28448]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K18575;K18575	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016803//ether hydrolase activity;GO:0042802//identical protein binding;GO:0047408//alkenylglycerophosphocholine hydrolase activity;GO:0047409//alkenylglycerophosphoethanolamine hydrolase activity	GO:0006629//lipid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0046485//ether lipid metabolic process	--
ENSG00000180090	0	0	0	0	0	0	0	0	0	0	0	0	OR3A1	olfactory receptor family 3 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8282]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180096	0.302	0.307	0.663	0.458	0.134	0.374	8	9	13	9	3	8	SEPTIN1	septin 1 [Source:HGNC Symbol;Acc:HGNC:2879]	Human Diseases	Infectious disease: bacterial	ko05100//Bacterial invasion of epithelial cells	K13737	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0008021//synaptic vesicle;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0031105//septin complex;GO:0032153//cell division site;GO:0072687//meiotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0007056//spindle assembly involved in female meiosis;GO:0017157//regulation of exocytosis;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0051311//meiotic metaphase plate congression;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000180098	5.762	4.852	4.572	5.499	4.06	4.899	215	182	126	152	128	133	TRNAU1AP	tRNA selenocysteine 1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30813]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0001514//selenocysteine incorporation;GO:0006412//translation	--
ENSG00000180104	25.821	27.417	25.948	25.667	26.608	21.912	1515.64	1632.4	1124.02	1131.66	1330.34	952.22	EXOC3	exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378]	-	-	-	-	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030426//growth cone;GO:0030496//midbody;GO:0030667//secretory granule membrane;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0051601//exocyst localization;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis	--
ENSG00000180113	0.081	0.011	0.015	0.125	0.09	0.067	15	2	2	17	14	9	TDRD6	tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339]	-	-	-	-	GO:0005737//cytoplasm;GO:0033391//chromatoid body;GO:0043186//P granule	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0034587//piRNA metabolic process	--
ENSG00000180116	0	0	0	0	0	0	0	0	0	0	0	0	C12orf40	chromosome 12 open reading frame 40 [Source:HGNC Symbol;Acc:HGNC:26846]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000180138	0	0	0	0	0	0	0	0	0	0	0	0	CSNK1A1L	casein kinase 1 alpha 1 like [Source:HGNC Symbol;Acc:HGNC:20289]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04340//Hedgehog signaling pathway	K08957;K08957;K08957;K08957;K08957;K08957;K08957;K08957	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000180155	23.021	26.961	25.719	27.695	27.68	28.493	1684.94	1739.78	1360.85	1512.87	1558.45	1453.04	LYNX1	Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25369	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0031225//anchored component of membrane;GO:0042995//cell projection	GO:0030548//acetylcholine receptor regulator activity;GO:0030550//acetylcholine receptor inhibitor activity;GO:0033130//acetylcholine receptor binding	GO:0099601//regulation of neurotransmitter receptor activity;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000180176	0	0	0	0	0.118	0	0	0	0	0	1	0	TH	tyrosine hydroxylase [Source:HGNC Symbol;Acc:HGNC:11782]	Metabolism;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Substance dependence;Nervous system;Endocrine system;Substance dependence;Substance dependence;Amino acid metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04917//Prolactin signaling pathway;ko05031//Amphetamine addiction;ko05030//Cocaine addiction;ko00350//Tyrosine metabolism;ko00790//Folate biosynthesis	K00501;K00501;K00501;K00501;K00501;K00501;K00501;K00501;K00501	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005790//smooth endoplasmic reticulum;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0009898//cytoplasmic side of plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	"GO:0004497//monooxygenase activity;GO:0004511//tyrosine 3-monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0016597//amino acid binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0034617//tetrahydrobiopterin binding;GO:0035240//dopamine binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0001666//response to hypoxia;GO:0001963//synaptic transmission, dopaminergic;GO:0001975//response to amphetamine;GO:0003007//heart morphogenesis;GO:0006585//dopamine biosynthetic process from tyrosine;GO:0006631//fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0007507//heart development;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0007612//learning;GO:0007613//memory;GO:0007617//mating behavior;GO:0007626//locomotory behavior;GO:0008016//regulation of heart contraction;GO:0009072//aromatic amino acid family metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0009414//response to water deprivation;GO:0009416//response to light stimulus;GO:0009635//response to herbicide;GO:0009651//response to salt stress;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010038//response to metal ion;GO:0010043//response to zinc ion;GO:0010259//multicellular organism aging;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0016137//glycoside metabolic process;GO:0017085//response to insecticide;GO:0018963//phthalate metabolic process;GO:0021987//cerebral cortex development;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0033076//isoquinoline alkaloid metabolic process;GO:0035094//response to nicotine;GO:0035176//social behavior;GO:0035900//response to isolation stress;GO:0035902//response to immobilization stress;GO:0042136//neurotransmitter biosynthetic process;GO:0042214//terpene metabolic process;GO:0042416//dopamine biosynthetic process;GO:0042418//epinephrine biosynthetic process;GO:0042421//norepinephrine biosynthetic process;GO:0042423//catecholamine biosynthetic process;GO:0042462//eye photoreceptor cell development;GO:0042745//circadian sleep/wake cycle;GO:0042755//eating behavior;GO:0043434//response to peptide hormone;GO:0043473//pigmentation;GO:0045471//response to ethanol;GO:0045472//response to ether;GO:0046684//response to pyrethroid;GO:0048545//response to steroid hormone;GO:0048596//embryonic camera-type eye morphogenesis;GO:0050890//cognition;GO:0051412//response to corticosterone;GO:0051602//response to electrical stimulus;GO:0052314//phytoalexin metabolic process;GO:0070848//response to growth factor;GO:0071287//cellular response to manganese ion;GO:0071312//cellular response to alkaloid;GO:0071316//cellular response to nicotine;GO:0071333//cellular response to glucose stimulus;GO:0071363//cellular response to growth factor stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:1990384//hyaloid vascular plexus regression"	--
ENSG00000180182	8.051	7.7	6.76	5.287	5.77	6.566	1113	976	691	605	697	669	MED14	mediator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:2370]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15156	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex;GO:0070847//core mediator complex	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0019827//stem cell population maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000180185	10.724	8.251	8.534	9.107	8.704	8.571	437.83	338	258	276	301	254	FAHD1	fumarylacetoacetate hydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14169]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism	K01557;K01557	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008948//oxaloacetate decarboxylase activity;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0018773//acetylpyruvate hydrolase activity;GO:0034545//fumarylpyruvate hydrolase activity;GO:0046872//metal ion binding;GO:0047621//acylpyruvate hydrolase activity	-	--
ENSG00000180190	17.038	14.37	16.747	13.896	14.438	17.242	1081	918	783	651	769	798	TDRP	testis development related protein [Source:HGNC Symbol;Acc:HGNC:26951]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function	GO:0007283//spermatogenesis	--
ENSG00000180198	11.995	11.403	12.986	12.361	10.761	13.891	568	507	475	403	415	462	RCC1	regulator of chromosome condensation 1 [Source:HGNC Symbol;Acc:HGNC:1913]	-	-	-	-	GO:0000785//chromatin;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0031491//nucleosome binding;GO:0031492//nucleosomal DNA binding;GO:0042393//histone binding;GO:0043199//sulfate binding;GO:0046982//protein heterodimerization activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation;GO:0007084//mitotic nuclear membrane reassembly;GO:0007088//regulation of mitotic nuclear division;GO:0016032//viral process;GO:0050790//regulation of catalytic activity;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000180205	0	0	0	0	0	0	0	0	0	0	0	0	WFDC9	WAP four-disulfide core domain 9 [Source:HGNC Symbol;Acc:HGNC:20380]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding	GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000180209	0.08	0	0.105	0.099	0.19	0	1	0	1	1	2	0	MYLPF	"myosin light chain, phosphorylatable, fast skeletal muscle [Source:HGNC Symbol;Acc:HGNC:29824]"	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04670//Leukocyte transendothelial migration	K12758;K12758;K12758;K12758;K12758	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0046872//metal ion binding	GO:0006936//muscle contraction;GO:0006955//immune response;GO:0007519//skeletal muscle tissue development;GO:0033275//actin-myosin filament sliding;GO:0060415//muscle tissue morphogenesis	--
ENSG00000180210	0	0	0	0	0	0	0	0	0	0	0	0	F2	"coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535]"	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Cell motility;Signal transduction;Immune system;Immune system	ko05200//Pathways in cancer;ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K01313;K01313;K01313;K01313;K01313;K01313;K01313;K01313	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001530//lipopolysaccharide binding;GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0070053//thrombospondin receptor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0006953//acute-phase response;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008284//positive regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0009611//response to wounding;GO:0010468//regulation of gene expression;GO:0010544//negative regulation of platelet activation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0030194//positive regulation of blood coagulation;GO:0030307//positive regulation of cell growth;GO:0032967//positive regulation of collagen biosynthetic process;GO:0042730//fibrinolysis;GO:0045861//negative regulation of proteolysis;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048712//negative regulation of astrocyte differentiation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051838//cytolysis by host of symbiont cells;GO:0051918//negative regulation of fibrinolysis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070945//neutrophil-mediated killing of gram-negative bacterium;GO:0090218//positive regulation of lipid kinase activity;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900182//positive regulation of protein localization to nucleus;GO:1900738//positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000180219	0	0	0	0	0	0	0	0	0	0	0	0	FAM71C	family with sequence similarity 71 member C [Source:HGNC Symbol;Acc:HGNC:28594]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000180228	12.394	11.943	11.828	11.046	9.905	11.321	454	425	316	293	303	292	PRKRA	protein activator of interferon induced protein kinase EIF2AK2 [Source:HGNC Symbol;Acc:HGNC:9438]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070578//RISC-loading complex	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016301//kinase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0070883//pre-miRNA binding	GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0016310//phosphorylation;GO:0030422//production of siRNA involved in RNA interference;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0034599//cellular response to oxidative stress;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0042473//outer ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0043583//ear development;GO:0048705//skeletal system morphogenesis;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000180233	3.532	2.999	3.525	3.494	3.351	3.159	232	198	171	170	186	151	ZNRF2	zinc and ring finger 2 [Source:HGNC Symbol;Acc:HGNC:22316]	-	-	-	-	GO:0001650//fibrillar center;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0032991//protein-containing complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000180245	1.019	1.348	1.666	1.486	2.334	0.978	39	51	49	44	76.13	28	RRH	retinal pigment epithelium-derived rhodopsin homolog [Source:HGNC Symbol;Acc:HGNC:10450]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000180251	0.092	0.125	0.016	0.633	0.49	0.456	8.07	11.01	1.01	41.01	36.16	29	SLC9A4	solute carrier family 9 member A4 [Source:HGNC Symbol;Acc:HGNC:11077]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K13961	GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0001696//gastric acid secretion;GO:0002064//epithelial cell development;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0009651//response to salt stress;GO:0051453//regulation of intracellular pH;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000180257	1.431	1.393	2.866	2.565	2.252	1.745	76	77	58	49.55	74	59	ZNF816	zinc finger protein 816 [Source:HGNC Symbol;Acc:HGNC:26995]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000180263	1.655	1.33	0.783	0.554	0.571	0.837	284	195	87	61	93	72	FGD6	"FYVE, RhoGEF and PH domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21740]"	-	-	-	-	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0030027//lamellipodium	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0046847//filopodium assembly	--
ENSG00000180264	0	0.044	0	0	0	0	0	3	0	0	0	0	ADGRD2	adhesion G protein-coupled receptor D2 [Source:HGNC Symbol;Acc:HGNC:18651]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway	--
ENSG00000180269	0	0	0	0	0	0	0	0	0	0	0	0	GPR139	G protein-coupled receptor 139 [Source:HGNC Symbol;Acc:HGNC:19995]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008188//neuropeptide receptor activity;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000180287	84.456	71.347	80.031	67.326	66.39	67.935	6227	5469	4026	3716	4259	3792	PLD5	phospholipase D family member 5 [Source:HGNC Symbol;Acc:HGNC:26879]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity	-	--
ENSG00000180304	43.923	40.153	43.934	42.858	37.386	41.833	1731	1619	1301	1244	1259	1221	OAZ2	ornithine decarboxylase antizyme 2 [Source:HGNC Symbol;Acc:HGNC:8096]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008073//ornithine decarboxylase inhibitor activity	GO:0006595//polyamine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0043086//negative regulation of catalytic activity;GO:0045732//positive regulation of protein catabolic process;GO:0050790//regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport;GO:1902268//negative regulation of polyamine transmembrane transport	--
ENSG00000180305	0	0	0	0	0	0	0	0	0	0	0	0	WFDC10A	WAP four-disulfide core domain 10A [Source:HGNC Symbol;Acc:HGNC:16139]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response	--
ENSG00000180316	0	0	0	0	0	0	0	0	0	0	0	0	PNPLA1	patatin like phospholipase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21246]	-	-	-	-	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0016020//membrane	"GO:0004806//triglyceride lipase activity;GO:0016740//transferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0016787//hydrolase activity;GO:0030280//structural constituent of skin epidermis;GO:0106341//omega-hydroxyceramide transacylase activity"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0030216//keratinocyte differentiation;GO:0046513//ceramide biosynthetic process;GO:0055088//lipid homeostasis;GO:0061436//establishment of skin barrier;GO:0106342//omega-hydroxyceramide biosynthetic process	--
ENSG00000180318	0.072	0.108	0.098	0.147	0.214	0.099	2	3	2	3	5	2	ALX1	ALX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:1494]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001755//neural crest cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000180329	7.876	8.256	7.216	5.925	6.414	6.064	339	363	233	188	237	193	CCDC43	coiled-coil domain containing 43 [Source:HGNC Symbol;Acc:HGNC:26472]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000180332	0.113	0.203	0.092	0.123	0.484	0.281	5	9	3	4	18	9	KCTD4	potassium channel tetramerization domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23227]	-	-	-	-	-	GO:0005515//protein binding	GO:0051260//protein homooligomerization	--
ENSG00000180336	0.267	0.17	0.32	0.13	0.113	0.201	22	15	10	6	8	14	MEIOC	meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	"GO:0006302//double-strand break repair;GO:0007130//synaptonemal complex assembly;GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0048255//mRNA stabilization;GO:0048599//oocyte development;GO:0051310//metaphase plate congression;GO:0051321//meiotic cell cycle;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:0070192//chromosome organization involved in meiotic cell cycle"	--
ENSG00000180340	19.634	19.369	19.156	17.705	18.649	18.305	1539	1526	1109	1028	1235	1044	FZD2	frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235;K02235	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity	"GO:0003149//membranous septum morphogenesis;GO:0003150//muscular septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007608//sensory perception of smell;GO:0016055//Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0030855//epithelial cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060022//hard palate development;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060119//inner ear receptor cell development;GO:0060412//ventricular septum morphogenesis;GO:0090103//cochlea morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure"	--
ENSG00000180346	8.171	7.904	8.196	6.782	6.323	6.759	540	525	400	332	353	325	TIGD2	tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding	-	--
ENSG00000180347	0.032	0.028	0	0	0	0	3	4	0	0	0	0	ITPRID1	ITPR interacting domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27363]	-	-	-	-	-	GO:0005102//signaling receptor binding	-	--
ENSG00000180353	0.04	0.072	0.033	0	0.557	0	1	3	1	0	8	0	HCLS1	hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05131//Shigellosis;ko05205//Proteoglycans in cancer;ko04530//Tight junction;ko05100//Bacterial invasion of epithelial cells	K06106;K06106;K06106;K06106;K06106	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030427//site of polarized growth;GO:0030864//cortical actin cytoskeleton;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0044877//protein-containing complex binding;GO:0051015//actin filament binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0009725//response to hormone;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030041//actin filament polymerization;GO:0030218//erythrocyte differentiation;GO:0030833//regulation of actin filament polymerization;GO:0030854//positive regulation of granulocyte differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0042307//positive regulation of protein import into nucleus;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045651//positive regulation of macrophage differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0071345//cellular response to cytokine stimulus;GO:2000107//negative regulation of leukocyte apoptotic process;GO:2000251//positive regulation of actin cytoskeleton reorganization"	--
ENSG00000180354	15.978	17.321	16.469	14.701	12.883	12.09	1752	1843	1351	1143	1260	976	MTURN	"maturin, neural progenitor differentiation regulator homolog [Source:HGNC Symbol;Acc:HGNC:25457]"	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0046330//positive regulation of JNK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000180357	9.159	10.018	9.662	8.441	8.472	8.983	1711	1881	1333	1168	1337	1221	ZNF609	zinc finger protein 609 [Source:HGNC Symbol;Acc:HGNC:29003]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000291//regulation of myoblast proliferation;GO:2001224//positive regulation of neuron migration	Others
ENSG00000180370	15.039	14.454	13.983	12.341	13.2	13.762	1915	1850	1315	1164	1420	1275	PAK2	p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;Acc:HGNC:8591]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: bacterial;Signal transduction;Cell motility;Infectious disease: viral;Cellular community - eukaryotes;Development and regeneration;Immune system;Signal transduction;Cancer: specific types	ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04510//Focal adhesion;ko04360//Axon guidance;ko04660//T cell receptor signaling pathway;ko04012//ErbB signaling pathway;ko05211//Renal cell carcinoma	K04410;K04410;K04410;K04410;K04410;K04410;K04410;K04410;K04410;K04410	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030141//secretory granule;GO:0048471//perinuclear region of cytoplasm;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0030296//protein tyrosine kinase activator activity;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0106310//protein serine kinase activity	GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0003300//cardiac muscle hypertrophy;GO:0006468//protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034333//adherens junction assembly;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050770//regulation of axonogenesis;GO:0051493//regulation of cytoskeleton organization;GO:0051497//negative regulation of stress fiber assembly;GO:0060996//dendritic spine development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070830//bicellular tight junction assembly;GO:0071407//cellular response to organic cyclic compound;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0150105//protein localization to cell-cell junction;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	--
ENSG00000180376	1.67	1.134	1.091	0.574	1.037	1.238	104.65	71.07	52	27.21	54.4	57.42	CCDC66	coiled-coil domain containing 66 [Source:HGNC Symbol;Acc:HGNC:27709]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0030054//cell junction;GO:0034451//centriolar satellite;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity	GO:0001578//microtubule bundle formation;GO:0001895//retina homeostasis;GO:0030030//cell projection organization;GO:0050908//detection of light stimulus involved in visual perception;GO:0060271//cilium assembly;GO:1903564//regulation of protein localization to cilium	--
ENSG00000180383	0	0	0	0	0	0	0	0	0	0	0	0	DEFB124	defensin beta 124 [Source:HGNC Symbol;Acc:HGNC:18104]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0071224//cellular response to peptidoglycan;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000180386	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-7	keratin associated protein 9-7 [Source:HGNC Symbol;Acc:HGNC:18915]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000180398	71.229	67.206	66.926	55.388	56.644	63.163	5834	5365	3972	3221	3933	3758	MCFD2	"multiple coagulation factor deficiency 2, ER cargo receptor complex subunit [Source:HGNC Symbol;Acc:HGNC:18451]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000180423	3.906	3.317	2.447	2.323	2.375	1.952	113.7	92.1	65.27	61	73	51	HARBI1	harbinger transposase derived 1 [Source:HGNC Symbol;Acc:HGNC:26522]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0034451//centriolar satellite	GO:0004518//nuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000180424	0	0	0	0	0	0	0	0	0	0	0	0	DEFB123	defensin beta 123 [Source:HGNC Symbol;Acc:HGNC:18103]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000180425	3.608	4.396	3.44	3.246	3.689	4.967	148.16	181.46	104.35	98.76	128.01	148.42	C11orf71	chromosome 11 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:25937]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	-	-	--
ENSG00000180432	0	0.013	0	0.069	0	0	0	1	0	2	0	0	CYP8B1	cytochrome P450 family 8 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2653]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00120//Primary bile acid biosynthesis	K07431;K07431;K07431	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008397//sterol 12-alpha-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0033778//7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity;GO:0033779//5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006699//bile acid biosynthetic process;GO:0016125//sterol metabolic process;GO:0031667//response to nutrient levels;GO:0038183//bile acid signaling pathway;GO:0045797//positive regulation of intestinal cholesterol absorption;GO:0070723//response to cholesterol	--
ENSG00000180433	0	0	0	0	0	0	0	0	0	0	0	0	OR6K6	olfactory receptor family 6 subfamily K member 6 [Source:HGNC Symbol;Acc:HGNC:15033]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180440	0.031	0.108	0.063	0.105	0.129	0.043	2	7	3	5	7	2	SERTM1	serine rich and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33792]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000180447	17.062	17.341	19.199	24.979	24.314	27.515	1113	1137	925	1207	1340	1306	GAS1	growth arrest specific 1 [Source:HGNC Symbol;Acc:HGNC:4165]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K06232	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0008589//regulation of smoothened signaling pathway;GO:0010955//negative regulation of protein processing;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042981//regulation of apoptotic process;GO:0045165//cell fate commitment;GO:0045930//negative regulation of mitotic cell cycle;GO:0048589//developmental growth;GO:0051726//regulation of cell cycle;GO:0060628//regulation of ER to Golgi vesicle-mediated transport	--
ENSG00000180448	2.719	3.099	3.254	3.328	3.464	3.948	77	86	64	71	84	78	ARHGAP45	Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0042995//cell projection	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000180475	0	0	0	0	0	0	0	0	0	0	0	0	OR10Q1	olfactory receptor family 10 subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:15134]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180479	2.635	1.996	2.194	1.659	1.584	3.637	124	96	76	66	66	54	ZNF571	zinc finger protein 571 [Source:HGNC Symbol;Acc:HGNC:25000]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000180481	0.411	0.407	0.511	0.557	0.374	0.077	11	15	16	15	12	2	GLIPR1L2	GLIPR1 like 2 [Source:HGNC Symbol;Acc:HGNC:28592]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007339//binding of sperm to zona pellucida	--
ENSG00000180483	0	0	0	0	0	0	0	0	0	0	0	0	DEFB119	defensin beta 119 [Source:HGNC Symbol;Acc:HGNC:18099]	-	-	-	-	GO:0005576//extracellular region	GO:0001530//lipopolysaccharide binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061760//antifungal innate immune response	--
ENSG00000180488	6.908	5.318	5.455	4.455	5.334	5.16	769	565	454	379	475	427	MIGA1	mitoguardin 1 [Source:HGNC Symbol;Acc:HGNC:24741]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0008053//mitochondrial fusion	--
ENSG00000180509	0.341	0.059	0.273	0.285	0.213	0.146	22.79	3.85	13.15	13.78	10.56	7.28	KCNE1	potassium voltage-gated channel subfamily E regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:6240]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04894	GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030018//Z disc;GO:0045121//membrane raft	GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0031433//telethonin binding;GO:0044325//transmembrane transporter binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007605//sensory perception of sound;GO:0034765//regulation of ion transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071320//cellular response to cAMP;GO:0071805//potassium ion transmembrane transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086009//membrane repolarization;GO:0086011//membrane repolarization during action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090315//negative regulation of protein targeting to membrane;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:1902260//negative regulation of delayed rectifier potassium channel activity	--
ENSG00000180530	31.765	22.135	18.492	11.911	16.379	16.498	5075	3366	2178	1413	2210	1920	NRIP1	nuclear receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8001]	-	-	-	-	GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0030331//estrogen receptor binding;GO:0035259//glucocorticoid receptor binding;GO:0042826//histone deacetylase binding;GO:0042974//retinoic acid receptor binding;GO:0046965//retinoid X receptor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001543//ovarian follicle rupture;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007623//circadian rhythm;GO:0019915//lipid storage;GO:0030728//ovulation;GO:0032922//circadian regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0071392//cellular response to estradiol stimulus	--
ENSG00000180532	0	0	0	0	0	0	0	0	0	0	0	0	ZSCAN4	zinc finger and SCAN domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23709]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome"	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010833//telomere maintenance via telomere lengthening;GO:0045950//negative regulation of mitotic recombination	zf-C2H2
ENSG00000180535	2.032	2.859	1.686	1.485	2.141	1.661	137.5	152.66	84.25	74.41	122.41	70.28	BHLHA15	basic helix-loop-helix family member a15 [Source:HGNC Symbol;Acc:HGNC:22265]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08040	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0007030//Golgi organization;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010832//negative regulation of myotube differentiation;GO:0019722//calcium-mediated signaling;GO:0030182//neuron differentiation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048312//intracellular distribution of mitochondria;GO:0048469//cell maturation	bHLH
ENSG00000180537	1.671	1.635	1.296	2.127	0.953	1.099	118	118	65	69	52	57	RNF182	ring finger protein 182 [Source:HGNC Symbol;Acc:HGNC:28522]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000180543	4.494	4.288	4.557	4.895	5.23	4.939	414	397	310	334	407	331	TSPYL5	TSPY like 5 [Source:HGNC Symbol;Acc:HGNC:29367]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0008284//positive regulation of cell population proliferation;GO:0031398//positive regulation of protein ubiquitination;GO:0040008//regulation of growth;GO:0051897//positive regulation of protein kinase B signaling;GO:0071480//cellular response to gamma radiation	--
ENSG00000180549	0	0	0	0	0	0	0	0	0	0	0	0	FUT7	fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K07635;K07635	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	"GO:0001807//regulation of type IV hypersensitivity;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0002522//leukocyte migration involved in immune response;GO:0002523//leukocyte migration involved in inflammatory response;GO:0006486//protein glycosylation;GO:0006672//ceramide metabolic process;GO:0006954//inflammatory response;GO:0007566//embryo implantation;GO:0009312//oligosaccharide biosynthetic process;GO:0022407//regulation of cell-cell adhesion;GO:0022409//positive regulation of cell-cell adhesion;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:0045785//positive regulation of cell adhesion;GO:0046626//regulation of insulin receptor signaling pathway;GO:0060353//regulation of cell adhesion molecule production;GO:0097021//lymphocyte migration into lymphoid organs;GO:0097022//lymphocyte migration into lymph node;GO:1902624//positive regulation of neutrophil migration;GO:1903037//regulation of leukocyte cell-cell adhesion;GO:1903236//regulation of leukocyte tethering or rolling;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:1904994//regulation of leukocyte adhesion to vascular endothelial cell;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:2000389//regulation of neutrophil extravasation"	--
ENSG00000180573	9.289	10.108	15.768	15.927	11.048	23.759	157	167	222	218	171	283	H2AC6	H2A clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4733]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0008285//negative regulation of cell population proliferation	--
ENSG00000180574	0	0.037	0	0	0	0	0	2.01	0	0	0	0	EIF2S3B	eukaryotic translation initiation factor 2 subunit gamma B [Source:HGNC Symbol;Acc:HGNC:43863]	-	-	-	-	GO:0005850//eukaryotic translation initiation factor 2 complex	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0003743//translation initiation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0045903//positive regulation of translational fidelity	--
ENSG00000180592	0.407	0.325	0.089	0.128	0.372	0.455	27	33	9	8	21	21	SKIDA1	SKI/DACH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:32697]	-	-	-	-	-	-	-	--
ENSG00000180596	0.658	0.641	0.594	0.57	0.433	0.603	9	7	6	5	5	6	H2BC4	H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000180611	2.723	2.318	2.77	2.72	2.795	2.574	173	148	130	128	150	119	MB21D2	Mab-21 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30438]	-	-	-	-	-	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding	-	--
ENSG00000180613	19.538	18.377	18.042	18.479	17.89	20.001	678	641	460	475	521	505	GSX2	GS homeobox 2 [Source:HGNC Symbol;Acc:HGNC:24959]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007389//pattern specification process;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0021527//spinal cord association neuron differentiation;GO:0021544//subpallium development;GO:0021575//hindbrain morphogenesis;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021889//olfactory bulb interneuron differentiation;GO:0021978//telencephalon regionalization;GO:0030334//regulation of cell migration;GO:0045747//positive regulation of Notch signaling pathway;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0048853//forebrain morphogenesis;GO:0060163//subpallium neuron fate commitment"	Homeobox
ENSG00000180616	0.019	0.019	0.008	0	0	0.009	3	3	1	0	0	1	SSTR2	somatostatin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11331]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Digestive system	"ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04971//Gastric acid secretion"	K04218;K04218;K04218;K04218	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0004930//G protein-coupled receptor activity;GO:0004994//somatostatin receptor activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0006937//regulation of muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0021549//cerebellum development;GO:0030432//peristalsis;GO:0030900//forebrain development;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus"	--
ENSG00000180626	1.771	1.602	1.639	0.87	1.233	1.529	161	153	96	65	96	78	ZNF594	zinc finger protein 594 [Source:HGNC Symbol;Acc:HGNC:29392]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000180628	7.034	4.114	4.406	3.972	4.523	5.783	1035	611	480	434	562	620	PCGF5	polycomb group ring finger 5 [Source:HGNC Symbol;Acc:HGNC:28264]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11489	GO:0000805//X chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0036353//histone H2A-K119 monoubiquitination;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060819//inactivation of X chromosome by genetic imprinting	--
ENSG00000180638	0.689	0.548	0.498	0.31	0.206	0.221	30	24	16	10	8	7	SLC47A2	solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0022857//transmembrane transporter activity;GO:0042910//xenobiotic transmembrane transporter activity	GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000180644	0	0	0	0	0.069	0	0	0	0	0	3	0	PRF1	perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360]	Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Immune system;Cell growth and death;Cardiovascular disease;Immune disease;Immune disease;Endocrine and metabolic disease;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04210//Apoptosis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K07818;K07818;K07818;K07818;K07818;K07818;K07818	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031904//endosome lumen;GO:0044194//cytolytic granule	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0022829//wide pore channel activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001771//immunological synapse formation;GO:0001913//T cell mediated cytotoxicity;GO:0002357//defense response to tumor cell;GO:0002418//immune response to tumor cell;GO:0006915//apoptotic process;GO:0006968//cellular defense response;GO:0019835//cytolysis;GO:0051260//protein homooligomerization;GO:0051607//defense response to virus;GO:0051712//positive regulation of killing of cells of other organism;GO:0055085//transmembrane transport	--
ENSG00000180658	0	0	0	0	0	0	0	0	0	0	0	0	OR2A4	olfactory receptor family 2 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:14729]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032154//cleavage furrow;GO:0055037//recycling endosome;GO:0090543//Flemming body;GO:0097431//mitotic spindle pole;GO:1990023//mitotic spindle midzone	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0032467//positive regulation of cytokinesis;GO:0032956//regulation of actin cytoskeleton organization;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180660	51.735	47.684	50.044	42.606	46.384	50.295	3113	2884	2224	1899	2358	2202	MAB21L1	mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0001654//eye development;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0043010//camera-type eye development	--
ENSG00000180667	6.045	5.519	5.919	4.152	3.845	5.501	802	736	580	408	431	531	YOD1	YOD1 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:25035]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13719	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0101005//deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	"GO:0006508//proteolysis;GO:0006986//response to unfolded protein;GO:0016236//macroautophagy;GO:0016579//protein deubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0035523//protein K29-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol;GO:1990167//protein K27-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination"	--
ENSG00000180694	18.28	16.521	16.649	15.425	14.349	19.187	1546	1459	1077	1060	1064	1151	TMEM64	transmembrane protein 64 [Source:HGNC Symbol;Acc:HGNC:25441]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0043462//regulation of ATPase activity;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000180697	0	0	0	0	0	0	0	0	0	0	0	0	C3orf22	chromosome 3 open reading frame 22 [Source:HGNC Symbol;Acc:HGNC:28534]	-	-	-	-	-	-	-	--
ENSG00000180708	0	0	0	0	0	0	0	0	0	0	0	0	OR10K2	olfactory receptor family 10 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:14826]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180720	0.238	0.665	0.216	0.791	0.733	0.681	15	35	5	37	35	25	CHRM4	cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953]	Environmental Information Processing;Cellular Processes;Organismal Systems	Signaling molecules and interaction;Cell motility;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04810//Regulation of actin cytoskeleton;ko04725//Cholinergic synapse	K04132;K04132;K04132	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0040012//regulation of locomotion;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000180730	1.354	2.033	1.239	1.27	1.232	1.137	108	163	73	75	83	66	SHISA2	shisa family member 2 [Source:HGNC Symbol;Acc:HGNC:20366]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030178//negative regulation of Wnt signaling pathway;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway	--
ENSG00000180739	11.155	12.073	12.054	12.362	13.387	16.382	529	549	410	437	532	564	S1PR5	sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04071//Sphingolipid signaling pathway	K04295;K04295	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0038036//sphingosine-1-phosphate receptor activity	GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0045664//regulation of neuron differentiation	--
ENSG00000180745	0	0.042	0	0	0	0	0	1	0	0	0	0	CLRN3	clarin 3 [Source:HGNC Symbol;Acc:HGNC:20795]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000180758	1.382	1.689	1.52	1.365	1.46	1.033	149	183	121	109	133	81	GPR157	G protein-coupled receptor 157 [Source:HGNC Symbol;Acc:HGNC:23687]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030154//cell differentiation;GO:0048512//circadian behavior;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0060019//radial glial cell differentiation	--
ENSG00000180767	0.025	0.1	0.306	0.238	0.387	0	1	4	9	7	13	0	CHST13	carbohydrate sulfotransferase 13 [Source:HGNC Symbol;Acc:HGNC:21755]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K07779	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047756//chondroitin 4-sulfotransferase activity	GO:0005975//carbohydrate metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000180772	0	0	0	0	0	0	0	0	0	0	0	0	AGTR2	angiotensin II receptor type 2 [Source:HGNC Symbol;Acc:HGNC:338]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Circulatory system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04261//Adrenergic signaling in cardiomyocytes;ko04614//Renin-angiotensin system	K04167;K04167;K04167	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding;GO:0048019//receptor antagonist activity	"GO:0001974//blood vessel remodeling;GO:0001991//regulation of systemic arterial blood pressure by circulatory renin-angiotensin;GO:0002033//angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0002035//brain renin-angiotensin system;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007199//G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0007263//nitric oxide mediated signal transduction;GO:0007420//brain development;GO:0008217//regulation of blood pressure;GO:0010459//negative regulation of heart rate;GO:0030308//negative regulation of cell growth;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035556//intracellular signal transduction;GO:0035566//regulation of metanephros size;GO:0035640//exploration behavior;GO:0038166//angiotensin-activated signaling pathway;GO:0042311//vasodilation;GO:0042981//regulation of apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0072300//positive regulation of metanephric glomerulus development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0097746//blood vessel diameter maintenance;GO:2000272//negative regulation of signaling receptor activity;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000180773	5.778	3.995	3.451	4.404	5.171	7.598	323	208	179	171	197	244	SLC36A4	solute carrier family 36 member 4 [Source:HGNC Symbol;Acc:HGNC:19660]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14209	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015171//amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015196//L-tryptophan transmembrane transporter activity;GO:0015293//symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015808//L-alanine transport;GO:0015824//proline transport;GO:0015827//tryptophan transport;GO:1904271//L-proline import across plasma membrane;GO:1904556//L-tryptophan transmembrane transport	--
ENSG00000180776	13.948	12.794	11.063	12.058	10.886	11.897	1283	1057	757	724	839	746	ZDHHC20	zinc finger DHHC-type palmitoyltransferase 20 [Source:HGNC Symbol;Acc:HGNC:20749]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0046872//metal ion binding;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation	--
ENSG00000180777	0.089	0.042	0	0	0.05	0.059	8	4	0	0	4	4	ANKRD30B	ankyrin repeat domain 30B [Source:HGNC Symbol;Acc:HGNC:24165]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000180785	0.095	0	0.067	0	0	0.023	6	0	3	0	0	1	OR51E1	olfactory receptor family 51 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:15194]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180787	0.077	0.038	0.052	0.039	0.034	0.053	8	4	4	3	3	4	ZFP3	ZFP3 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:12861]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000180801	1.069	1.082	0.711	0.689	0.652	0.888	78	83	46	44	43	59	ARSJ	arylsulfatase family member J [Source:HGNC Symbol;Acc:HGNC:26286]	-	-	-	-	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000180806	0	0	0	0	0	0	0	0	0	0	0	0	HOXC9	homeobox C9 [Source:HGNC Symbol;Acc:HGNC:5130]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016235//aggresome;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0045786//negative regulation of cell cycle;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000180815	6.285	5.451	3.888	2.658	3.75	3.221	636.09	547.47	290.57	192.71	320.63	237.17	MAP3K15	mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000180817	60.6	61.515	62.645	56.875	53.879	63.706	1624	1657	1208	1129	1186	1206	PPA1	inorganic pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:9226]	Metabolism	Energy metabolism	ko00190//Oxidative phosphorylation	K01507	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0000287//magnesium ion binding;GO:0004427//inorganic diphosphatase activity;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006796//phosphate-containing compound metabolic process	--
ENSG00000180818	0	0	0	0	0.108	0	0	0	0	0	1	0	HOXC10	homeobox C10 [Source:HGNC Symbol;Acc:HGNC:5122]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0021520//spinal cord motor neuron cell fate specification;GO:0030326//embryonic limb morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050905//neuromuscular process;GO:0120163//negative regulation of cold-induced thermogenesis"	Homeobox
ENSG00000180822	4.608	3.923	4.439	4.773	5.742	4.683	92	70	51	63	85.78	56	PSMG4	proteasome assembly chaperone 4 [Source:HGNC Symbol;Acc:HGNC:21108]	-	-	-	-	GO:0032991//protein-containing complex	GO:0044877//protein-containing complex binding	GO:0043248//proteasome assembly	--
ENSG00000180828	0.03	0.073	0.08	0.06	0.052	0.02	2	5	4	3	3	1	BHLHE22	basic helix-loop-helix family member e22 [Source:HGNC Symbol;Acc:HGNC:11963]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0022008//neurogenesis;GO:0030182//neuron differentiation"	bHLH
ENSG00000180834	2.361	2.221	2.221	3.467	3.67	4.932	93	93	70.24	103	129.82	138	MAP6D1	MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005801//cis-Golgi network;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005516//calmodulin binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0018009//N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000180855	0.764	1.186	0.957	0.531	0.843	1.004	40.76	63.61	37.74	21	38	39	ZNF443	zinc finger protein 443 [Source:HGNC Symbol;Acc:HGNC:20878]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process"	zf-C2H2
ENSG00000180871	0	0	0	0	0	0	0	0	0	0	0	0	CXCR2	C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027]	Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Signal transduction;Immune system;Signaling molecules and interaction;Infectious disease: bacterial	ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K05050;K05050;K05050;K05050;K05050;K05050;K05050	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0042629//mast cell granule;GO:0072686//mitotic spindle	GO:0004918//interleukin-8 receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0019959//interleukin-8 binding	GO:0002407//dendritic cell chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell population proliferation;GO:0019722//calcium-mediated signaling;GO:0030593//neutrophil chemotaxis;GO:0031623//receptor internalization;GO:0038112//interleukin-8-mediated signaling pathway;GO:0042119//neutrophil activation;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000180872	0	0	0	0	0	0	0	0	0	0	0	0	DEFB112	defensin beta 112 [Source:HGNC Symbol;Acc:HGNC:18093]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000180875	0	0.023	0.078	0.062	0.014	0.048	0	2	5	4	1	3	GREM2	"gremlin 2, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:17655]"	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K23318	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008201//heparin binding;GO:0036122//BMP binding;GO:0042802//identical protein binding;GO:0048018//receptor ligand activity	GO:0009887//animal organ morphogenesis;GO:0010172//embryonic body morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0038098//sequestering of BMP from receptor via BMP binding;GO:0048263//determination of dorsal identity;GO:0060300//regulation of cytokine activity	--
ENSG00000180878	0.125	0	0	0.113	0.049	0	3	0	0	2	1	0	C11orf42	chromosome 11 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:28541]	-	-	-	-	-	-	-	--
ENSG00000180879	112.695	120.386	121.806	131.252	109.433	111.978	1447	1542	1150	1243	1188	1046	SSR4	signal sequence receptor subunit 4 [Source:HGNC Symbol;Acc:HGNC:11326]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K04571	GO:0005783//endoplasmic reticulum;GO:0005784//Sec61 translocon complex;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	-	-	--
ENSG00000180881	0.306	0.811	0.318	0.15	0.165	0.786	17	19	10	8	7	17	CAPS2	calcyphosine 2 [Source:HGNC Symbol;Acc:HGNC:16471]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000180884	1.799	1.332	1.599	1.932	1.487	1.33	133	113	92	110	106	79	ZNF792	zinc finger protein 792 [Source:HGNC Symbol;Acc:HGNC:24751]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000180891	21.044	20.699	22.023	27.877	24.237	24.252	1338	1241	1075	1113	1301	1112	CUEDC1	CUE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:31350]	-	-	-	-	-	GO:0005515//protein binding;GO:0043130//ubiquitin binding	-	--
ENSG00000180900	21.392	22.331	27.357	27.563	27.105	28.018	2174	2339	2004	1897	2146	1995	SCRIB	scribble planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:30377]	Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Signal transduction	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis;ko04530//Tight junction;ko04390//Hippo signaling pathway	K16175;K16175;K16175;K16175	GO:0001772//immunological synapse;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0034750//Scrib-APC-beta-catenin complex;GO:0035748//myelin sheath abaxonal region;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0044291//cell-cell contact zone;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099147//extrinsic component of postsynaptic density membrane	GO:0005515//protein binding;GO:0045296//cadherin binding	"GO:0001768//establishment of T cell polarity;GO:0001843//neural tube closure;GO:0001921//positive regulation of receptor recycling;GO:0002093//auditory receptor cell morphogenesis;GO:0008104//protein localization;GO:0008283//cell population proliferation;GO:0016080//synaptic vesicle targeting;GO:0016331//morphogenesis of embryonic epithelium;GO:0016477//cell migration;GO:0021747//cochlear nucleus development;GO:0030154//cell differentiation;GO:0030859//polarized epithelial cell differentiation;GO:0032729//positive regulation of interferon-gamma production;GO:0035089//establishment of apical/basal cell polarity;GO:0036342//post-anal tail morphogenesis;GO:0042060//wound healing;GO:0043065//positive regulation of apoptotic process;GO:0043113//receptor clustering;GO:0043615//astrocyte cell migration;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0045930//negative regulation of mitotic cell cycle;GO:0046007//negative regulation of activated T cell proliferation;GO:0048488//synaptic vesicle endocytosis;GO:0050918//positive chemotaxis;GO:0060088//auditory receptor cell stereocilium organization;GO:0060122//inner ear receptor cell stereocilium organization;GO:0060561//apoptotic process involved in morphogenesis;GO:0060603//mammary gland duct morphogenesis;GO:0071896//protein localization to adherens junction;GO:0090630//activation of GTPase activity;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0098968//neurotransmitter receptor transport postsynaptic membrane to endosome;GO:0099003//vesicle-mediated transport in synapse;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization"	--
ENSG00000180901	17.797	18.074	18.939	19.621	19.24	21.018	1350	1378	1061	1102	1233	1160	KCTD2	potassium channel tetramerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21294]	-	-	-	-	GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:0097602//cullin family protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051260//protein homooligomerization	--
ENSG00000180902	2.495	4.128	3.19	4.919	3.701	4.019	153	175	123	144	171	122	D2HGDH	D-2-hydroxyglutarate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:28358]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003824//catalytic activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051990//(R)-2-hydroxyglutarate dehydrogenase activity;GO:0071949//FAD binding	GO:0006103//2-oxoglutarate metabolic process;GO:0006108//malate metabolic process;GO:0010042//response to manganese ion;GO:0010043//response to zinc ion;GO:0032025//response to cobalt ion;GO:0044267//cellular protein metabolic process	--
ENSG00000180914	4.93	4.089	3.51	5.271	5.658	5.334	437	374	204	320	435	322	OXTR	oxytocin receptor [Source:HGNC Symbol;Acc:HGNC:8529]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04921//Oxytocin signaling pathway	K04229;K04229;K04229;K04229	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0004930//G protein-coupled receptor activity;GO:0004990//oxytocin receptor activity;GO:0005000//vasopressin receptor activity;GO:0017046//peptide hormone binding;GO:0042277//peptide binding	"GO:0001967//suckling behavior;GO:0001975//response to amphetamine;GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007507//heart development;GO:0007565//female pregnancy;GO:0007595//lactation;GO:0007613//memory;GO:0009410//response to xenobiotic stimulus;GO:0010701//positive regulation of norepinephrine secretion;GO:0014070//response to organic cyclic compound;GO:0021537//telencephalon development;GO:0030431//sleep;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0034059//response to anoxia;GO:0034097//response to cytokine;GO:0035176//social behavior;GO:0042220//response to cocaine;GO:0042711//maternal behavior;GO:0042713//sperm ejaculation;GO:0042755//eating behavior;GO:0043434//response to peptide hormone;GO:0044058//regulation of digestive system process;GO:0044849//estrous cycle;GO:0045777//positive regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0048545//response to steroid hormone;GO:0048565//digestive tract development;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060137//maternal process involved in parturition;GO:0060406//positive regulation of penile erection;GO:0060455//negative regulation of gastric acid secretion;GO:0070371//ERK1 and ERK2 cascade;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000180917	6.866	8.166	7.846	10.086	8.009	7.742	676	617	486	465	578	538	CMTR2	cap methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:25635]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0006370//7-methylguanosine mRNA capping;GO:0006397//mRNA processing;GO:0032259//methylation;GO:0097309//cap1 mRNA methylation;GO:0097310//cap2 mRNA methylation	--
ENSG00000180919	0	0	0	0	0	0.058	0	0	0	0	0	1	OR56B4	olfactory receptor family 56 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:15248]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180921	6.354	6.293	7.476	7.911	7.903	7.158	746	742	645	687	780	611	FAM83H	family with sequence similarity 83 member H [Source:HGNC Symbol;Acc:HGNC:24797]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:1990254//keratin filament binding	GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0031214//biomineral tissue development;GO:0044380//protein localization to cytoskeleton;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000180929	0.25	0.181	0.277	0.307	0.727	0.782	11	8	9	10	27	25	GPR62	G protein-coupled receptor 62 [Source:HGNC Symbol;Acc:HGNC:13301]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:1990763//arrestin family protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0048016//inositol phosphate-mediated signaling	--
ENSG00000180934	0	0	0	0	0	0	0	0	0	0	0	0	OR56A1	olfactory receptor family 56 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:14781]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180938	0.368	0.395	0.339	0.218	0.122	0.445	25	27	17	11	7	22	ZNF572	zinc finger protein 572 [Source:HGNC Symbol;Acc:HGNC:26758]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000180953	1.072	1.477	0.896	0.947	1.115	1.866	12.75	16.58	7.57	7.92	10.78	15.7	ST20	suppressor of tumorigenicity 20 [Source:HGNC Symbol;Acc:HGNC:33520]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Cell growth and death;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04064//NF-kappa B signaling pathway;ko04210//Apoptosis;ko05221//Acute myeloid leukemia	K02162;K02162;K02162;K02162	-	GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process	GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030308//negative regulation of cell growth;GO:0071494//cellular response to UV-C;GO:0097190//apoptotic signaling pathway;GO:1902512//positive regulation of apoptotic DNA fragmentation	--
ENSG00000180957	18.402	19.797	17.257	15.848	14.183	16.919	1046	913	700	576	674	649	PITPNB	phosphatidylinositol transfer protein beta [Source:HGNC Symbol;Acc:HGNC:9002]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0008289//lipid binding;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transfer activity;GO:0031210//phosphatidylcholine binding;GO:0035091//phosphatidylinositol binding;GO:0120019//phosphatidylcholine transfer activity;GO:0140338//sphingomyelin transfer activity	"GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006997//nucleus organization;GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer"	--
ENSG00000180964	67.107	64.334	63.966	58.826	49.59	56.217	1536	1501	1076	975	943	917	TCEAL8	transcription elongation factor A like 8 [Source:HGNC Symbol;Acc:HGNC:28683]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0050699//WW domain binding	-	--
ENSG00000180974	0	0	0	0	0	0	0	0	0	0	0	0	OR52E4	olfactory receptor family 52 subfamily E member 4 [Source:HGNC Symbol;Acc:HGNC:15213]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180979	4.276	4.44	4.383	3.739	3.776	5.226	318	329	275	188.85	239	246	LRRC57	leucine rich repeat containing 57 [Source:HGNC Symbol;Acc:HGNC:26719]	-	-	-	-	GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000180988	0	0	0	0	0	0	0	0	0	0	0	0	OR52N2	olfactory receptor family 52 subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:15228]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000180992	13.199	15.738	14.256	16.051	12.701	15.648	262	314	209	236	213	226	MRPL14	mitochondrial ribosomal protein L14 [Source:HGNC Symbol;Acc:HGNC:14279]	Genetic Information Processing	Translation	ko03010//Ribosome	K02874	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000180998	1.608	0.765	1.057	1.225	0.476	0.713	111	67	68	68	35	44	GPR137C	G protein-coupled receptor 137C [Source:HGNC Symbol;Acc:HGNC:25445]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:1904263//positive regulation of TORC1 signaling	--
ENSG00000180999	0.109	0	0	0	0	0	2	0	0	0	0	0	C1orf105	chromosome 1 open reading frame 105 [Source:HGNC Symbol;Acc:HGNC:29591]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000181001	0	0.019	0.026	0	0	0	0	1	1	0	0	0	OR52N1	olfactory receptor family 52 subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:14853]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181004	3.454	3.704	3.609	2.472	2.961	3.049	232	238	179	123	168	149	BBS12	Bardet-Biedl syndrome 12 [Source:HGNC Symbol;Acc:HGNC:26648]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0042073//intraciliary transport;GO:0042755//eating behavior;GO:0045494//photoreceptor cell maintenance;GO:0045599//negative regulation of fat cell differentiation;GO:0051131//chaperone-mediated protein complex assembly	--
ENSG00000181007	1.789	1.335	1.746	1.297	1.277	1.604	208	157	130	106	133	111	ZFP82	ZFP82 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:28682]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181009	0	0	0	0	0	0	0	0	0	0	0	0	OR52N5	olfactory receptor family 52 subfamily N member 5 [Source:HGNC Symbol;Acc:HGNC:15231]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181016	0.16	0	0.044	0	0	0.051	3.28	0	1.25	0	0	1.43	LSMEM1	leucine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:22036]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000181017	0	0	0	0	0	0	0	0	0	0	0	0	OR56B2P	olfactory receptor family 56 subfamily B member 2 pseudogene [Source:HGNC Symbol;Acc:HGNC:15246]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181019	17.765	19.362	14.787	24.656	21.274	23.262	575	596	369	591	575	544	NQO1	NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K00355;K00355;K00355;K00355;K00355;K00355	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0045202//synapse	"GO:0003723//RNA binding;GO:0003955//NAD(P)H dehydrogenase (quinone) activity;GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0004784//superoxide dismutase activity;GO:0005515//protein binding;GO:0008753//NADPH dehydrogenase (quinone) activity;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding;GO:0050136//NADH dehydrogenase (quinone) activity"	"GO:0002931//response to ischemia;GO:0006116//NADH oxidation;GO:0006743//ubiquinone metabolic process;GO:0006801//superoxide metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0006979//response to oxidative stress;GO:0007271//synaptic transmission, cholinergic;GO:0007568//aging;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0009725//response to hormone;GO:0009743//response to carbohydrate;GO:0010033//response to organic substance;GO:0014070//response to organic cyclic compound;GO:0014075//response to amine;GO:0019430//removal of superoxide radicals;GO:0032355//response to estradiol;GO:0033574//response to testosterone;GO:0034599//cellular response to oxidative stress;GO:0042360//vitamin E metabolic process;GO:0042373//vitamin K metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043279//response to alkaloid;GO:0043525//positive regulation of neuron apoptotic process;GO:0045454//cell redox homeostasis;GO:0045471//response to ethanol;GO:0051602//response to electrical stimulus;GO:0070301//cellular response to hydrogen peroxide;GO:0070995//NADPH oxidation;GO:0071248//cellular response to metal ion;GO:1901698//response to nitrogen compound;GO:1903363//negative regulation of cellular protein catabolic process;GO:1904772//response to tetrachloromethane;GO:1904844//response to L-glutamine;GO:1904880//response to hydrogen sulfide;GO:1905395//response to flavonoid"	--
ENSG00000181023	0	0	0	0	0	0	0	0	0	0	0	0	OR56B1	olfactory receptor family 56 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:15245]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181026	0.659	1.249	1.211	0.975	1.56	1.79	42	80	57	46	84	83	AEN	apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0031965//nuclear membrane	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000181027	9.298	7.081	11.197	7.86	9.317	9.687	398	361	335	286	333	320	FKRP	fukutin related protein [Source:HGNC Symbol;Acc:HGNC:17997]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K19873;K19873	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	"GO:0002162//dystroglycan binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0042802//identical protein binding"	GO:0006486//protein glycosylation;GO:0009101//glycoprotein biosynthetic process;GO:0016485//protein processing;GO:0035269//protein O-linked mannosylation;GO:0051262//protein tetramerization	--
ENSG00000181029	27.411	31.394	29.412	40.485	34.342	38.001	524	609.01	403	557	568	504	TRAPPC5	trafficking protein particle complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:23067]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:1990070//TRAPPI protein complex;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0048193//Golgi vesicle transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000181031	0.281	0.906	0.673	1.501	0.896	1.693	15	40	21	37	31	24	RPH3AL	rabphilin 3A like (without C2 domains) [Source:HGNC Symbol;Acc:HGNC:10296]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0006887//exocytosis;GO:0017157//regulation of exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0032024//positive regulation of insulin secretion;GO:0042593//glucose homeostasis;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway	--
ENSG00000181035	5.165	5.741	6.594	5.379	6.41	6.592	350	391	330	270	367	325	SLC25A42	solute carrier family 25 member 42 [Source:HGNC Symbol;Acc:HGNC:28380]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005347//ATP transmembrane transporter activity;GO:0005515//protein binding;GO:0015217//ADP transmembrane transporter activity;GO:0015228//coenzyme A transmembrane transporter activity;GO:0043262//adenosine-diphosphatase activity;GO:0080122//AMP transmembrane transporter activity	GO:0015866//ADP transport;GO:0015867//ATP transport;GO:0035349//coenzyme A transmembrane transport;GO:0055085//transmembrane transport;GO:0080121//AMP transport	--
ENSG00000181036	0	0	0	0	0	0	0	0	0	0	0	0	FCRL6	Fc receptor like 6 [Source:HGNC Symbol;Acc:HGNC:31910]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0019903//protein phosphatase binding;GO:0042289//MHC class II protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000181038	12.527	11.18	14.35	14.42	12.259	13.543	242	219	219	212	207	196	METTL23	methyltransferase like 23 [Source:HGNC Symbol;Acc:HGNC:26988]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0031072//heat shock protein binding;GO:0140297//DNA-binding transcription factor binding	GO:0032259//methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050890//cognition	--
ENSG00000181045	12.953	14.009	15.953	14.7	17.658	15.506	670	716	601	554	710	658	SLC26A11	solute carrier family 26 member 11 [Source:HGNC Symbol;Acc:HGNC:14471]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity	GO:0006811//ion transport;GO:0008272//sulfate transport;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport	--
ENSG00000181061	70.816	63.115	59.04	63.264	57.575	66.161	2090.53	1937.17	1364.77	1404.57	1445.4	1409.38	HIGD1A	HIG1 hypoxia inducible domain family member 1A [Source:HGNC Symbol;Acc:HGNC:29527]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0070469//respirasome	-	GO:0043066//negative regulation of apoptotic process;GO:0097250//mitochondrial respirasome assembly	--
ENSG00000181072	0.073	0.075	0.043	0.033	0.057	0.056	9	4	2	3	2	5	CHRM2	cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signal transduction;Signal transduction;Cell motility;Nervous system	ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04725//Cholinergic synapse	K04130;K04130;K04130;K04130;K04130;K04130	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032279//asymmetric synapse;GO:0032280//symmetric synapse;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0098981//cholinergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity;GO:1990763//arrestin family protein binding	"GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007207//phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0008016//regulation of heart contraction;GO:0009615//response to virus;GO:0095500//acetylcholine receptor signaling pathway;GO:0098664//G protein-coupled serotonin receptor signaling pathway;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000181074	0	0	0	0	0	0	0	0	0	0	0	0	OR52N4	olfactory receptor family 52 subfamily N member 4 [Source:HGNC Symbol;Acc:HGNC:15230]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181085	1.943	3.267	3.077	1.728	1.372	1.929	66	120	71	45	45	41	MAPK15	mitogen-activated protein kinase 15 [Source:HGNC Symbol;Acc:HGNC:24667]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K19603	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0072687//meiotic spindle	GO:0000166//nucleotide binding;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0003400//regulation of COPII vesicle coating;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007029//endoplasmic reticulum organization;GO:0008284//positive regulation of cell population proliferation;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0030336//negative regulation of cell migration;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:0051973//positive regulation of telomerase activity;GO:0090494//dopamine uptake;GO:1902017//regulation of cilium assembly;GO:1904355//positive regulation of telomere capping;GO:1904491//protein localization to ciliary transition zone;GO:1905188//positive regulation of metaphase/anaphase transition of meiosis I;GO:1905832//positive regulation of spindle assembly	--
ENSG00000181090	26.701	27.774	30.255	26.042	28.108	26.702	1841	1958	1454	1326	1598	1427	EHMT1	euchromatic histone lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24650]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Aging;Amino acid metabolism	ko01100//Metabolic pathways;ko04211//Longevity regulating pathway;ko00310//Lysine degradation	K11420;K11420;K11420	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body	GO:0001222//transcription corepressor binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0046976//histone methyltransferase activity (H3-K27 specific);GO:0070742//C2H2 zinc finger domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0016571//histone methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation;GO:0034968//histone lysine methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051567//histone H3-K9 methylation;GO:0070734//histone H3-K27 methylation;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000181092	0	0	0	0	0.251	0	0	0	0	0	20	0	ADIPOQ	"adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633]"	Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease;Signal transduction;Aging;Endocrine system;Endocrine system;Endocrine and metabolic disease	ko04932//Non-alcoholic fatty liver disease;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus	K07296;K07296;K07296;K07296;K07296;K07296;K07296	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0032991//protein-containing complex;GO:0062023//collagen-containing extracellular matrix	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005179//hormone activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0033691//sialic acid binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	"GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0006006//glucose metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006635//fatty acid beta-oxidation;GO:0007165//signal transduction;GO:0007584//response to nutrient;GO:0007623//circadian rhythm;GO:0009410//response to xenobiotic stimulus;GO:0009617//response to bacterium;GO:0009744//response to sucrose;GO:0009749//response to glucose;GO:0009967//positive regulation of signal transduction;GO:0010467//gene expression;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0010739//positive regulation of protein kinase A signaling;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010875//positive regulation of cholesterol efflux;GO:0010906//regulation of glucose metabolic process;GO:0014823//response to activity;GO:0019395//fatty acid oxidation;GO:0030336//negative regulation of cell migration;GO:0030853//negative regulation of granulocyte differentiation;GO:0031667//response to nutrient levels;GO:0031953//negative regulation of protein autophosphorylation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032757//positive regulation of interleukin-8 production;GO:0032869//cellular response to insulin stimulus;GO:0033034//positive regulation of myeloid cell apoptotic process;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034383//low-density lipoprotein particle clearance;GO:0034612//response to tumor necrosis factor;GO:0042593//glucose homeostasis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043407//negative regulation of MAP kinase activity;GO:0045471//response to ethanol;GO:0045599//negative regulation of fat cell differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0045721//negative regulation of gluconeogenesis;GO:0045776//negative regulation of blood pressure;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045923//positive regulation of fatty acid metabolic process;GO:0046326//positive regulation of glucose import;GO:0046888//negative regulation of hormone secretion;GO:0050728//negative regulation of inflammatory response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050765//negative regulation of phagocytosis;GO:0050805//negative regulation of synaptic transmission;GO:0050873//brown fat cell differentiation;GO:0051384//response to glucocorticoid;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070543//response to linoleic acid;GO:0070994//detection of oxidative stress;GO:0071320//cellular response to cAMP;GO:0071466//cellular response to xenobiotic stimulus;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0071872//cellular response to epinephrine stimulus;GO:0072659//protein localization to plasma membrane;GO:0090317//negative regulation of intracellular protein transport;GO:0110113//positive regulation of lipid transporter activity;GO:0120162//positive regulation of cold-induced thermogenesis;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900121//negative regulation of receptor binding;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:2000279//negative regulation of DNA biosynthetic process;GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:2000478//positive regulation of metanephric glomerular visceral epithelial cell development;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:2000534//positive regulation of renal albumin absorption;GO:2000584//negative regulation of platelet-derived growth factor receptor-alpha signaling pathway;GO:2000590//negative regulation of metanephric mesenchymal cell migration"	--
ENSG00000181104	77.682	66.24	54.103	21.759	24.523	23.272	5881	5147	3089	1246	1574	1309	F2R	coagulation factor II thrombin receptor [Source:HGNC Symbol;Acc:HGNC:3537]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Signaling molecules and interaction;Signal transduction;Infectious disease: bacterial;Signal transduction;Cell motility;Signal transduction;Signal transduction;Immune system;Immune system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04611//Platelet activation;ko04610//Complement and coagulation cascades	K03914;K03914;K03914;K03914;K03914;K03914;K03914;K03914;K03914;K03914;K03914	GO:0005576//extracellular region;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031094//platelet dense tubular network;GO:0031594//neuromuscular junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0001965//G-protein alpha-subunit binding;GO:0004930//G protein-coupled receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015057//thrombin-activated receptor activity;GO:0031681//G-protein beta-subunit binding	"GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0003105//negative regulation of glomerular filtration;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0007529//establishment of synaptic specificity at neuromuscular junction;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009611//response to wounding;GO:0009653//anatomical structure morphogenesis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0030194//positive regulation of blood coagulation;GO:0030335//positive regulation of cell migration;GO:0032496//response to lipopolysaccharide;GO:0032651//regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0045217//cell-cell junction maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045907//positive regulation of vasoconstriction;GO:0045987//positive regulation of smooth muscle contraction;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048873//homeostasis of number of cells within a tissue;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051928//positive regulation of calcium ion transport;GO:0051930//regulation of sensory perception of pain;GO:0060155//platelet dense granule organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070493//thrombin-activated receptor signaling pathway;GO:0099553//trans-synaptic signaling by endocannabinoid, modulating synaptic transmission;GO:1900134//negative regulation of renin secretion into blood stream"	--
ENSG00000181109	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000181135	5.783	4.679	5.871	4.964	5.135	4.52	172	146	156	124	115	125	ZNF707	zinc finger protein 707 [Source:HGNC Symbol;Acc:HGNC:27815]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181143	0	0	0	0	0	0	0	0	0	0	0	0	MUC16	"mucin 16, cell surface associated [Source:HGNC Symbol;Acc:HGNC:15582]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019898//extrinsic component of membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007155//cell adhesion	--
ENSG00000181163	301.17	284.987	275.471	264.229	241.849	244.434	8329	7919	5610	5412	5642	4921	NPM1	nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031616//spindle pole centrosome;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:1990904//ribonucleoprotein complex	GO:0001046//core promoter sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030957//Tat protein binding;GO:0042393//histone binding;GO:0042803//protein homodimerization activity;GO:0043023//ribosomal large subunit binding;GO:0043024//ribosomal small subunit binding;GO:0051059//NF-kappaB binding;GO:0051082//unfolded protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000055//ribosomal large subunit export from nucleus;GO:0000056//ribosomal small subunit export from nucleus;GO:0006281//DNA repair;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006407//rRNA export from nucleus;GO:0006886//intracellular protein transport;GO:0006913//nucleocytoplasmic transport;GO:0007098//centrosome cycle;GO:0007165//signal transduction;GO:0007569//cell aging;GO:0008104//protein localization;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010824//regulation of centrosome duplication;GO:0010826//negative regulation of centrosome duplication;GO:0032071//regulation of endodeoxyribonuclease activity;GO:0034644//cellular response to UV;GO:0042255//ribosome assembly;GO:0042273//ribosomal large subunit biogenesis;GO:0042274//ribosomal small subunit biogenesis;GO:0043066//negative regulation of apoptotic process;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045727//positive regulation of translation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046599//regulation of centriole replication;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060699//regulation of endoribonuclease activity;GO:0060735//regulation of eIF2 alpha phosphorylation by dsRNA;GO:1902629//regulation of mRNA stability involved in cellular response to UV;GO:1902751//positive regulation of cell cycle G2/M phase transition"	--
ENSG00000181191	15.171	16.737	18.133	15.74	15.839	15.86	761	803	677	585	663	571	PJA1	praja ring finger ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:16648]	-	-	-	-	GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010738//regulation of protein kinase A signaling;GO:0016567//protein ubiquitination;GO:0030163//protein catabolic process;GO:0035329//hippo signaling	--
ENSG00000181192	6.487	6.968	6.89	8.185	7.567	8.539	686	659	546	593	686	640	DHTKD1	dehydrogenase E1 and transketolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23537]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00380//Tryptophan metabolism	K15791;K15791;K15791	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0030976//thiamine pyrophosphate binding"	GO:0002244//hematopoietic progenitor cell differentiation;GO:0006091//generation of precursor metabolites and energy;GO:0006096//glycolytic process;GO:0006099//tricarboxylic acid cycle	--
ENSG00000181195	0.266	0.28	0.569	0.054	0.143	0.424	5	7	5	1	3	8	PENK	proenkephalin [Source:HGNC Symbol;Acc:HGNC:8831]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K18832	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0032280//symmetric synapse;GO:0034466//chromaffin granule lumen;GO:0034592//synaptic vesicle lumen;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043679//axon terminus;GO:0070852//cell body fiber;GO:0099013//neuronal dense core vesicle lumen	GO:0001515//opioid peptide activity;GO:0005184//neuropeptide hormone activity;GO:0031628//opioid receptor binding	"GO:0001649//osteoblast differentiation;GO:0001662//behavioral fear response;GO:0001666//response to hypoxia;GO:0001964//startle response;GO:0002118//aggressive behavior;GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007568//aging;GO:0007600//sensory perception;GO:0007626//locomotory behavior;GO:0009314//response to radiation;GO:0009617//response to bacterium;GO:0009636//response to toxic substance;GO:0014009//glial cell proliferation;GO:0019233//sensory perception of pain;GO:0032355//response to estradiol;GO:0032496//response to lipopolysaccharide;GO:0034599//cellular response to oxidative stress;GO:0035094//response to nicotine;GO:0035641//locomotory exploration behavior;GO:0043278//response to morphine;GO:0045471//response to ethanol;GO:0051592//response to calcium ion;GO:0051867//general adaptation syndrome, behavioral process;GO:0071305//cellular response to vitamin D;GO:0071320//cellular response to cAMP;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071871//response to epinephrine;GO:0098586//cellular response to virus;GO:0099538//synaptic signaling via neuropeptide;GO:2000987//positive regulation of behavioral fear response"	--
ENSG00000181214	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000181215	0	0	0.011	0.006	0	0	0	0	2	1.16	0	0	C4orf50	chromosome 4 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:33766]	-	-	-	-	-	-	-	--
ENSG00000181218	33.142	26.828	37.791	41.295	41.42	45.15	502	419	416	495	537	477	H2AW	H2A.W histone [Source:HGNC Symbol;Acc:HGNC:20507]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006337//nucleosome disassembly;GO:0070914//UV-damage excision repair	--
ENSG00000181220	6.326	6.61	5.496	5.36	5.995	6.073	505	531	324	319	408	354	ZNF746	zinc finger protein 746 [Source:HGNC Symbol;Acc:HGNC:21948]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization;GO:1901216//positive regulation of neuron death"	zf-C2H2
ENSG00000181222	21.157	24.666	25.575	27.46	29.491	26.622	2770	3246	2473	2663	3262	2536	POLR2A	RNA polymerase II subunit A [Source:HGNC Symbol;Acc:HGNC:9187]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03006;K03006	GO:0000791//euchromatin;GO:0005634//nucleus;GO:0031981//nuclear lumen	GO:0001046//core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0014070//response to organic cyclic compound;GO:0071453//cellular response to oxygen levels"	--
ENSG00000181234	0.102	0.213	0.202	0.201	0.187	0.115	11	23	16	16	17	9	TMEM132C	transmembrane protein 132C [Source:HGNC Symbol;Acc:HGNC:25436]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000181240	0.489	0.418	0.325	0.51	0.528	0.302	15	13	7	11	13	7	SLC25A41	solute carrier family 25 member 41 [Source:HGNC Symbol;Acc:HGNC:28533]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity	GO:0015866//ADP transport;GO:0015867//ATP transport;GO:0055085//transmembrane transport;GO:0140021//mitochondrial ADP transmembrane transport;GO:1990544//mitochondrial ATP transmembrane transport	--
ENSG00000181264	8.194	8.659	9.149	8.348	8.86	10.741	534	501	414	398	442	460	TLCD5	TLC domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28280]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000181273	0	0	0	0	0	0	0	0	0	0	0	0	OR5AK2	olfactory receptor family 5 subfamily AK member 2 [Source:HGNC Symbol;Acc:HGNC:15251]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181274	4.62	5.005	6.139	5.072	5.724	6.736	214	233	210	174	224	227	FRAT2	FRAT regulator of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:16048]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer	K03096;K03096;K03096;K03096;K03096;K03096;K03096	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function	GO:0016055//Wnt signaling pathway;GO:0046825//regulation of protein export from nucleus;GO:1904886//beta-catenin destruction complex disassembly	--
ENSG00000181282	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000181284	4.294	4.293	6.241	6.493	5.458	5.997	175	176	188	196	188	178	TMEM102	transmembrane protein 102 [Source:HGNC Symbol;Acc:HGNC:26722]	-	-	-	-	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0010820//positive regulation of T cell chemotaxis;GO:0034097//response to cytokine;GO:0042981//regulation of apoptotic process;GO:0045785//positive regulation of cell adhesion;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:1901028//regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2000406//positive regulation of T cell migration	--
ENSG00000181291	0.075	0.085	0.093	0.101	0.122	0.212	9	10	8	9	12	18	TMEM132E	transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044297//cell body	GO:0003674//molecular_function	GO:0035677//posterior lateral line neuromast hair cell development	--
ENSG00000181315	11.95	9.808	9.188	9.013	8.92	9.035	1068	950	646	600	677	623	ZNF322	zinc finger protein 322 [Source:HGNC Symbol;Acc:HGNC:23640]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:1902459//positive regulation of stem cell population maintenance"	zf-C2H2
ENSG00000181322	0.393	0.625	0.182	0.206	0.335	0.192	16	28	6	6	8	4	NME9	NME/NM23 family member 9 [Source:HGNC Symbol;Acc:HGNC:21343]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0120293//dynein axonemal particle	GO:0004550//nucleoside diphosphate kinase activity	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process	--
ENSG00000181323	0	0	0	0	0	0	0	0	0	0	0	0	SPEM1	spermatid maturation 1 [Source:HGNC Symbol;Acc:HGNC:32429]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0007291//sperm individualization;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility	--
ENSG00000181333	0.017	0	0	0.022	0	0	2	0	0	2	0	0	HEPHL1	hephaestin like 1 [Source:HGNC Symbol;Acc:HGNC:30477]	Organismal Systems;Metabolism	Digestive system;Metabolism of cofactors and vitamins	ko04978//Mineral absorption;ko00860//Porphyrin metabolism	K14735;K14735	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006825//copper ion transport;GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0055072//iron ion homeostasis	--
ENSG00000181350	4.897	5.151	5.626	6.951	5.058	4.935	330	348	280	347	288	242	LRRC75A	leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000181371	0	0	0	0	0	0	0	0	0	0	0	0	OR5M8	olfactory receptor family 5 subfamily M member 8 [Source:HGNC Symbol;Acc:HGNC:14846]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181374	0	0	0	0	0	0	0	0	0	0	0	0	CCL13	C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K16595;K16595;K16595;K16595	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0030593//neutrophil chemotaxis;GO:0031640//killing of cells of other organism;GO:0043547//positive regulation of GTPase activity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0060326//cell chemotaxis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000181378	0.159	0.037	0.134	0.069	0.226	0.059	10	4	9	5	5	1	CFAP65	cilia and flagella associated protein 65 [Source:HGNC Symbol;Acc:HGNC:25325]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007288//sperm axoneme assembly;GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility	--
ENSG00000181381	0.592	1.202	0.292	0.224	0.925	0.885	61	63	27	21	46	32	DDX60L	DExD/H-box 60 like [Source:HGNC Symbol;Acc:HGNC:26429]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000181392	0.048	0.166	0.056	0	0.34	0	1	3	1	0	7	0	SYNE4	spectrin repeat containing nuclear envelope family member 4 [Source:HGNC Symbol;Acc:HGNC:26703]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031309//integral component of nuclear outer membrane;GO:0034993//meiotic nuclear membrane microtubule tethering complex	GO:0005515//protein binding	GO:0045198//establishment of epithelial cell apical/basal polarity	--
ENSG00000181396	13.662	13.459	17.688	15.561	15.828	16.073	696	742	612	632.47	730	618.74	OGFOD3	2-oxoglutarate and iron dependent oxygenase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26174]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	-	--
ENSG00000181404	13.194	13.397	16.111	15.872	14.324	17.126	495.06	499.99	437.23	440.86	444.49	462.55	WASHC1	WASH complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24361]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18461	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0071203//WASH complex	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043014//alpha-tubulin binding;GO:0043015//gamma-tubulin binding	"GO:0006887//exocytosis;GO:0010507//negative regulation of autophagy;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0022617//extracellular matrix disassembly;GO:0030335//positive regulation of cell migration;GO:0031274//positive regulation of pseudopodium assembly;GO:0031396//regulation of protein ubiquitination;GO:0032456//endocytic recycling;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0042147//retrograde transport, endosome to Golgi;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity"	--
ENSG00000181408	2.027	2.027	2.224	3.09	3.495	3.005	154.9	155.72	125.53	174.97	225.66	167.1	UTS2R	urotensin 2 receptor [Source:HGNC Symbol;Acc:HGNC:4468]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04241	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001604//urotensin II receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0097746//blood vessel diameter maintenance	--
ENSG00000181409	3.055	2.568	2.666	2.809	3.292	2.978	424.17	371.59	283.5	305.06	348.27	275.06	AATK	apoptosis associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:21]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007420//brain development;GO:0008150//biological_process;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038083//peptidyl-tyrosine autophosphorylation	--
ENSG00000181418	0.013	0.101	0	0.017	0	0	1	8	0	1	0	0	DDN	dendrin [Source:HGNC Symbol;Acc:HGNC:24458]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032591//dendritic spine membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045202//synapse;GO:0045211//postsynaptic membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005515//protein binding"	GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000181433	0	0	0	0	0	0	0	0	0	0	0	0	SAGE1	sarcoma antigen 1 [Source:HGNC Symbol;Acc:HGNC:30369]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000181444	2.915	2.599	4.223	3.865	3.761	4.816	155	150	160	164	179	198	ZNF467	zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181449	0.288	0.21	0.364	0.104	0.273	0.211	15	11	14	4	12	8	SOX2	SRY-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11195]	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells	K16796;K16796	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0001654//eye development;GO:0001714//endodermal cell fate specification;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0009611//response to wounding;GO:0009653//anatomical structure morphogenesis;GO:0010468//regulation of gene expression;GO:0021781//glial cell fate commitment;GO:0021983//pituitary gland development;GO:0021984//adenohypophysis development;GO:0022409//positive regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0035019//somatic stem cell population maintenance;GO:0042246//tissue regeneration;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0045165//cell fate commitment;GO:0045597//positive regulation of cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048731//system development;GO:0048839//inner ear development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070848//response to growth factor;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:1902807//negative regulation of cell cycle G1/S phase transition"	HMG
ENSG00000181450	2.246	1.759	1.381	2.053	1.533	1.051	164	133	92	79	101	78	ZNF678	zinc finger protein 678 [Source:HGNC Symbol;Acc:HGNC:28652]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181458	8.089	8.652	7.102	8.504	9.253	7.976	246	263	178	198	243	169	TMEM45A	transmembrane protein 45A [Source:HGNC Symbol;Acc:HGNC:25480]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000181467	2.462	2.563	2.276	2.564	3.083	3.178	429	449	293	331	454	403	RAP2B	"RAP2B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9862]"	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0035579//specific granule membrane;GO:0044291//cell-cell contact zone;GO:0045121//membrane raft;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0019904//protein domain specific binding	GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0030336//negative regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032486//Rap protein signal transduction;GO:0061097//regulation of protein tyrosine kinase activity;GO:0070527//platelet aggregation	--
ENSG00000181472	4.63	3.756	3.618	3.943	3.402	5.082	298	243	172	188	185	238	ZBTB2	zinc finger and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20868]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000181481	6.91	8.505	7.776	9.866	9.386	7.982	279	333	243	300	324	233	RNF135	ring finger protein 135 [Source:HGNC Symbol;Acc:HGNC:21158]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:1990904//ribonucleoprotein complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0039552//RIG-I binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0002376//immune system process;GO:0010994//free ubiquitin chain polymerization;GO:0016567//protein ubiquitination;GO:0032728//positive regulation of interferon-beta production;GO:0039529//RIG-I signaling pathway;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0051260//protein homooligomerization;GO:0070534//protein K63-linked ubiquitination;GO:0140374//antiviral innate immune response	--
ENSG00000181499	0	0	0	0	0	0	0	0	0	0	0	0	OR6T1	olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000181513	4.881	3.935	5.789	5.311	5.75	5.512	170	142	154	145	175	147	ACBD4	acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006631//fatty acid metabolic process	--
ENSG00000181518	0	0	0	0	0	0	0	0	0	0	0	0	OR8D4	olfactory receptor family 8 subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:14840]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181523	16.611	17.44	18.185	17.399	17.357	17.33	904	947	722	698	803	680	SGSH	N-sulfoglucosamine sulfohydrolase [Source:HGNC Symbol;Acc:HGNC:10818]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01565;K01565;K01565	GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016250//N-sulfoglucosamine sulfohydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006027//glycosaminoglycan catabolic process;GO:0030200//heparan sulfate proteoglycan catabolic process	--
ENSG00000181541	98.375	95.119	105.912	78.498	86.618	86.246	5189	5043	4126	3067	3860	3310	MAB21L2	mab-21 like 2 [Source:HGNC Symbol;Acc:HGNC:6758]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0001654//eye development;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0010172//embryonic body morphogenesis;GO:0043010//camera-type eye development	--
ENSG00000181544	0.293	0.158	0.295	0.115	0.146	0.362	35	13	21	6	14	31	FANCB	FA complementation group B [Source:HGNC Symbol;Acc:HGNC:3583]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10889	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0036297//interstrand cross-link repair;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:1990414//replication-born double-strand break repair via sister chromatid exchange;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000181552	0	0.052	0	0	0	0	0	1	0	0	0	0	EDDM3B	epididymal protein 3B [Source:HGNC Symbol;Acc:HGNC:19223]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	-	--
ENSG00000181555	10.488	7.888	6.805	4.042	5.323	6.022	1547	1100	740	448	677	646	SETD2	"SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11423;K11423	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031981//nuclear lumen	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043014//alpha-tubulin binding;GO:0046872//metal ion binding;GO:0046975//histone methyltransferase activity (H3-K36 specific)	"GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0001763//morphogenesis of a branching structure;GO:0001843//neural tube closure;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0010452//histone H3-K36 methylation;GO:0010468//regulation of gene expression;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010793//regulation of mRNA export from nucleus;GO:0018023//peptidyl-lysine trimethylation;GO:0018026//peptidyl-lysine monomethylation;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0032259//methylation;GO:0032465//regulation of cytokinesis;GO:0032727//positive regulation of interferon-alpha production;GO:0034340//response to type I interferon;GO:0034728//nucleosome organization;GO:0034968//histone lysine methylation;GO:0035441//cell migration involved in vasculogenesis;GO:0035987//endodermal cell differentiation;GO:0045087//innate immune response;GO:0048332//mesoderm morphogenesis;GO:0048568//embryonic organ development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048863//stem cell differentiation;GO:0048864//stem cell development;GO:0051607//defense response to virus;GO:0060039//pericardium development;GO:0060669//embryonic placenta morphogenesis;GO:0060977//coronary vasculature morphogenesis;GO:0097198//histone H3-K36 trimethylation;GO:0097676//histone H3-K36 dimethylation;GO:1902850//microtubule cytoskeleton organization involved in mitosis;GO:1905634//regulation of protein localization to chromatin"	--
ENSG00000181562	0.103	0.051	0.14	0	0	0.071	2	1	2	0	0	1	EDDM3A	epididymal protein 3A [Source:HGNC Symbol;Acc:HGNC:16978]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0007321//sperm displacement	--
ENSG00000181585	0	0	0.24	0	0	0	0	0	6	0	0	0	TMIE	transmembrane inner ear [Source:HGNC Symbol;Acc:HGNC:30800]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis	--
ENSG00000181588	7.84	7.41	7.201	5.959	6.097	7.592	430	419	301	240	291	331	MEX3D	mex-3 RNA binding family member D [Source:HGNC Symbol;Acc:HGNC:16734]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0046872//metal ion binding	GO:0010609//mRNA localization resulting in posttranscriptional regulation of gene expression;GO:0061157//mRNA destabilization	--
ENSG00000181609	0	0	0	0	0	0	0	0	0	0	0	0	OR52D1	olfactory receptor family 52 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:15212]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181610	18.497	17.586	20.417	20.801	15.799	22.052	425	486	318	345	338	360	MRPS23	mitochondrial ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:14509]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0031965//nuclear membrane	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000181616	0	0	0	0	0	0	0	0	0	0	0	0	OR52H1	olfactory receptor family 52 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:15218]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181617	0.094	0.187	0	0	0.111	0	1	2	0	0	1	0	FDCSP	follicular dendritic cell secreted protein [Source:HGNC Symbol;Acc:HGNC:19215]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000181619	1.875	1.052	0.89	1.068	0.9	0.991	170	99	63	71	70	67	GPR135	G protein-coupled receptor 135 [Source:HGNC Symbol;Acc:HGNC:19991]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:1990763//arrestin family protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000181625	0.104	0	0	1.572	1.126	0	1.65	0	0	28.14	22.98	0	SLX1B	"SLX1 homolog B, structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:28748]"	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15078	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0033557//Slx1-Slx4 complex	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0016787//hydrolase activity;GO:0017108//5'-flap endonuclease activity;GO:0046872//metal ion binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0010833//telomere maintenance via telomere lengthening;GO:0061820//telomeric D-loop disassembly;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090656//t-circle formation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904431//positive regulation of t-circle formation	--
ENSG00000181626	0	0	0	0	0	0	0	0	0	0	0	0	ANKRD62	ankyrin repeat domain 62 [Source:HGNC Symbol;Acc:HGNC:35241]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000181631	0	0	0	0	0	0	0	0	0	0	0	0	P2RY13	purinergic receptor P2Y13 [Source:HGNC Symbol;Acc:HGNC:4537]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K08388	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008150//biological_process;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0071407//cellular response to organic cyclic compound	--
ENSG00000181634	0	0	0	0	0.017	0	0	0	0	0	2	0	TNFSF15	TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05478	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity	--
ENSG00000181638	4.915	5.049	5.217	4.314	5.089	6.4	427.39	448.77	337.18	275.69	366.15	391	ZFP41	ZFP41 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:26786]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	zf-C2H2
ENSG00000181649	0.943	1.512	0.639	0.071	0.372	0.072	18	29	9	1	6	1	PHLDA2	pleckstrin homology like domain family A member 2 [Source:HGNC Symbol;Acc:HGNC:12385]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0001890//placenta development;GO:0006915//apoptotic process;GO:0009887//animal organ morphogenesis;GO:0010468//regulation of gene expression;GO:0030334//regulation of cell migration;GO:0043065//positive regulation of apoptotic process;GO:0045995//regulation of embryonic development;GO:0060721//regulation of spongiotrophoblast cell proliferation;GO:0070873//regulation of glycogen metabolic process;GO:1903547//regulation of growth hormone activity	--
ENSG00000181652	0.147	0.042	0.071	0.056	0	0	11.51	4	5	3	0	0	ATG9B	autophagy related 9B [Source:HGNC Symbol;Acc:HGNC:21899]	Cellular Processes;Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K17907;K17907;K17907	GO:0000139//Golgi membrane;GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034045//phagophore assembly site membrane;GO:0055038//recycling endosome membrane	GO:0017128//phospholipid scramblase activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0010940//positive regulation of necrotic cell death;GO:0017121//plasma membrane phospholipid scrambling;GO:0034497//protein localization to phagophore assembly site;GO:0044805//late nucleophagy;GO:0060349//bone morphogenesis	--
ENSG00000181656	0.097	0.22	0.056	0	0.033	0.095	7	16	3	0	2	5	GPR88	G protein-coupled receptor 88 [Source:HGNC Symbol;Acc:HGNC:4539]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003774//cytoskeletal motor activity;GO:0004930//G protein-coupled receptor activity;GO:0008020//G protein-coupled photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0007626//locomotory behavior;GO:0009584//detection of visible light;GO:0019228//neuronal action potential;GO:0050885//neuromuscular process controlling balance;GO:0061743//motor learning;GO:0071482//cellular response to light stimulus	--
ENSG00000181666	21.458	20.103	22.701	21.9	22.085	25.408	935	967	723	759	862	836	ZNF875	zinc finger protein 875 [Source:HGNC Symbol;Acc:HGNC:4928]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181690	5.112	3.426	3.134	2.462	3.406	3.616	465	330	253	208	261	262	PLAG1	PLAG1 zinc finger [Source:HGNC Symbol;Acc:HGNC:9045]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0022612//gland morphogenesis;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060252//positive regulation of glial cell proliferation;GO:0060736//prostate gland growth"	zf-C2H2
ENSG00000181693	0	0	0	0	0	0	0	0	0	0	0	0	OR8H1	olfactory receptor family 8 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:14824]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181698	0	0	0	0	0	0	0	0	0	0	0	0	OR5T1	olfactory receptor family 5 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14821]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181704	8.629	7.006	8.192	7.728	6.817	8.242	1011	869	716	681	677	748	YIPF6	Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]	-	-	-	-	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0060576//intestinal epithelial cell development	--
ENSG00000181718	0	0	0	0	0	0	0	0	0	0	0	0	OR5T2	olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181722	1.502	0.671	0.585	0.559	0.707	0.583	848	380	244	233	336	230	ZBTB20	zinc finger and BTB domain containing 20 [Source:HGNC Symbol;Acc:HGNC:13503]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010629//negative regulation of gene expression;GO:0032728//positive regulation of interferon-beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0045821//positive regulation of glycolytic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046889//positive regulation of lipid biosynthetic process;GO:0055088//lipid homeostasis;GO:0071333//cellular response to glucose stimulus"	ZBTB
ENSG00000181733	0	0	0	0	0	0	0	0	0	0	0	0	OR2Z1	olfactory receptor family 2 subfamily Z member 1 [Source:HGNC Symbol;Acc:HGNC:15391]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181744	19.931	14.375	16.103	10.222	11.446	14.867	1560	1201	922	633	792	883	DIPK2A	divergent protein kinase domain 2A [Source:HGNC Symbol;Acc:HGNC:28490]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0030126//COPI vesicle coat;GO:0030137//COPI-coated vesicle;GO:0031410//cytoplasmic vesicle	-	GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0060038//cardiac muscle cell proliferation;GO:1900020//positive regulation of protein kinase C activity	--
ENSG00000181751	2.255	1.803	1.918	2.201	2.389	3.001	118	110	79	89	112	112	MACIR	macrophage immunometabolism regulator [Source:HGNC Symbol;Acc:HGNC:25052]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0035869//ciliary transition zone;GO:0042995//cell projection	GO:0005515//protein binding	GO:0006954//inflammatory response;GO:0010764//negative regulation of fibroblast migration;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0050728//negative regulation of inflammatory response;GO:0060271//cilium assembly;GO:1900016//negative regulation of cytokine production involved in inflammatory response	--
ENSG00000181752	0	0	0	0	0	0	0	0	0	0	0	0	OR8K5	olfactory receptor family 8 subfamily K member 5 [Source:HGNC Symbol;Acc:HGNC:15315]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181754	5.272	6.066	5.79	5.354	5.786	6.352	561	600	455	422	499	437	AMIGO1	adhesion molecule with Ig like domain 1 [Source:HGNC Symbol;Acc:HGNC:20824]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:1990030//pericellular basket	GO:0005515//protein binding;GO:0015459//potassium channel regulator activity	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007413//axonal fasciculation;GO:0007420//brain development;GO:0010976//positive regulation of neuron projection development;GO:0030154//cell differentiation;GO:0042552//myelination;GO:0050772//positive regulation of axonogenesis;GO:0051965//positive regulation of synapse assembly;GO:0106030//neuron projection fasciculation;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity;GO:1905232//cellular response to L-glutamate	--
ENSG00000181761	0	0	0	0	0	0	0	0	0	0	0	0	OR8H3	olfactory receptor family 8 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:15309]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181767	0	0	0	0	0	0	0	0	0	0	0	0	OR8H2	olfactory receptor family 8 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:15308]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181773	0.09	0.202	0	0	0.053	0.124	4	9	0	0	2	4	GPR3	G protein-coupled receptor 3 [Source:HGNC Symbol;Acc:HGNC:4484]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0040020//regulation of meiotic nuclear division;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000181778	0.688	0.951	0.673	0.826	0.634	0.158	18	25	13	16	14	3	TMEM252	transmembrane protein 252 [Source:HGNC Symbol;Acc:HGNC:28537]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000181781	0.121	0.034	0.047	0	0	0.048	4	1	1	0	0	1	ODF3L2	outer dense fiber of sperm tails 3 like 2 [Source:HGNC Symbol;Acc:HGNC:26841]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule	GO:0005515//protein binding	-	--
ENSG00000181785	0	0	0	0	0	0	0	0	0	0	0	0	OR5AS1	olfactory receptor family 5 subfamily AS member 1 [Source:HGNC Symbol;Acc:HGNC:15261]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181786	0	0	0	0	0	0	0	0	0	0	0	0	ACTL9	actin like 9 [Source:HGNC Symbol;Acc:HGNC:28494]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0033011//perinuclear theca;GO:0061827//sperm head	GO:0005515//protein binding	GO:0001675//acrosome assembly;GO:0009566//fertilization	--
ENSG00000181788	11.808	13.532	12.005	13.181	14.939	17.203	566	652	425	468	605	600	SIAH2	siah E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:10858]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle	GO:0003714//transcription corepressor activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0007275//multicellular organism development;GO:0016567//protein ubiquitination;GO:0031396//regulation of protein ubiquitination;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044257//cellular protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0060070//canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1990000//amyloid fibril formation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000181789	57.061	62.114	57.791	49.761	52.708	55.841	3643	3986	2725	2345	2843	2594	COPG1	COPI coat complex subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:2236]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0051683//establishment of Golgi localization;GO:0072384//organelle transport along microtubule	--
ENSG00000181790	0.079	0.113	0.071	0.024	0.052	0.085	9	13	6	2	5	8	ADGRB1	adhesion G protein-coupled receptor B1 [Source:HGNC Symbol;Acc:HGNC:943]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K04596	GO:0001891//phagocytic cup;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0001530//lipopolysaccharide binding;GO:0001786//phosphatidylserine binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding	"GO:0002376//immune system process;GO:0006909//phagocytosis;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007422//peripheral nervous system development;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell population proliferation;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0031397//negative regulation of protein ubiquitination;GO:0042177//negative regulation of protein catabolic process;GO:0043277//apoptotic cell clearance;GO:0043652//engulfment of apoptotic cell;GO:0045087//innate immune response;GO:0048167//regulation of synaptic plasticity;GO:0050829//defense response to Gram-negative bacterium;GO:0051965//positive regulation of synapse assembly;GO:1901741//positive regulation of myoblast fusion;GO:1903428//positive regulation of reactive oxygen species biosynthetic process"	--
ENSG00000181803	0	0	0	0	0	0	0	0	0	0	0	0	OR6S1	olfactory receptor family 6 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:15363]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181804	1.759	1.669	1.744	1.205	1.861	1.208	107	124	73	66	67	65	SLC9A9	solute carrier family 9 member A9 [Source:HGNC Symbol;Acc:HGNC:20653]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000181817	25.171	22.421	23.682	23.915	24.551	25.117	449	402	312	316	370	326	LSM10	"LSM10, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:HGNC:17562]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005683//U7 snRNP;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0071254//cytoplasmic U snRNP body	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0071208//histone pre-mRNA DCP binding;GO:0071209//U7 snRNA binding	GO:0006397//mRNA processing;GO:0006398//mRNA 3'-end processing by stem-loop binding and cleavage;GO:0008380//RNA splicing;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000181826	4.308	4.041	3.426	1.999	3.701	2.839	323	294.44	188.03	106	195.34	155	RELL1	RELT like 1 [Source:HGNC Symbol;Acc:HGNC:27379]	-	-	-	-	GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000181827	4.088	3.255	2.58	1.758	2.368	2.777	568	498	273	225	282	322	RFX7	regulatory factor X7 [Source:HGNC Symbol;Acc:HGNC:25777]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	RFX
ENSG00000181830	9.628	10.64	10.094	12.195	11.949	12.296	634	674	488	599	647	564	SLC35C1	solute carrier family 35 member C1 [Source:HGNC Symbol;Acc:HGNC:20197]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005457//GDP-fucose transmembrane transporter activity;GO:0015297//antiporter activity	GO:0008643//carbohydrate transport;GO:0030259//lipid glycosylation;GO:0036066//protein O-linked fucosylation;GO:0036085//GDP-fucose import into Golgi lumen;GO:0045746//negative regulation of Notch signaling pathway	--
ENSG00000181847	0	0	0	0	0.078	0	0	0	0	0	4	0	TIGIT	T cell immunoreceptor with Ig and ITIM domains [Source:HGNC Symbol;Acc:HGNC:26838]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K16350	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032695//negative regulation of interleukin-12 production;GO:0032733//positive regulation of interleukin-10 production;GO:0050868//negative regulation of T cell activation	--
ENSG00000181852	25.809	26.933	30.162	29.87	26.337	35.887	1266	1279	1166	1031	1122	1242	RNF41	ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K11981	GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0071782//endoplasmic reticulum tubular network	GO:0004842//ubiquitin-protein transferase activity;GO:0005128//erythropoietin receptor binding;GO:0005135//interleukin-3 receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0010498//proteasomal protein catabolic process;GO:0016567//protein ubiquitination;GO:0030336//negative regulation of cell migration;GO:0043408//regulation of MAPK cascade;GO:0045619//regulation of lymphocyte differentiation;GO:0045637//regulation of myeloid cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0051865//protein autoubiquitination;GO:0051896//regulation of protein kinase B signaling;GO:0097191//extrinsic apoptotic signaling pathway;GO:1901525//negative regulation of mitophagy;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000181856	2.389	2.545	2.495	3.796	4.238	3.806	152	166	129	171	218	174	SLC2A4	solute carrier family 2 member 4 [Source:HGNC Symbol;Acc:HGNC:11009]	Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Cardiovascular disease;Endocrine system;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease	ko05415//Diabetic cardiomyopathy;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus	K07191;K07191;K07191;K07191;K07191;K07191;K07191	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005905//clathrin-coated pit;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012505//endomembrane system;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030136//clathrin-coated vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030315//T-tubule;GO:0030659//cytoplasmic vesicle membrane;GO:0031982//vesicle;GO:0032593//insulin-responsive compartment;GO:0042383//sarcolemma;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0005355//glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0005975//carbohydrate metabolic process;GO:0007611//learning or memory;GO:0007614//short-term memory;GO:0007616//long-term memory;GO:0008643//carbohydrate transport;GO:0010021//amylopectin biosynthetic process;GO:0015749//monosaccharide transmembrane transport;GO:0031550//positive regulation of brain-derived neurotrophic factor receptor signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0042593//glucose homeostasis;GO:0044381//glucose import in response to insulin stimulus;GO:0045471//response to ethanol;GO:0046323//glucose import;GO:0050873//brown fat cell differentiation;GO:0055085//transmembrane transport;GO:0071356//cellular response to tumor necrosis factor;GO:0071456//cellular response to hypoxia;GO:0071470//cellular response to osmotic stress;GO:0098694//regulation of synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0150104//transport across blood-brain barrier;GO:1904659//glucose transmembrane transport	--
ENSG00000181867	0	0	0	0	0	0	0	0	0	0	0	0	FTMT	ferritin mitochondrial [Source:HGNC Symbol;Acc:HGNC:17345]	Cellular Processes	Cell growth and death	ko04216//Ferroptosis	K18495	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004322//ferroxidase activity;GO:0008198//ferrous iron binding;GO:0008199//ferric iron binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006880//intracellular sequestering of iron ion;GO:0008284//positive regulation of cell population proliferation;GO:0051349//positive regulation of lyase activity;GO:1904231//positive regulation of succinate dehydrogenase activity;GO:1904234//positive regulation of aconitate hydratase activity	--
ENSG00000181873	0.961	0.833	0.7	0.89	0.816	0.923	156	136	84	107	112	109	IBA57	iron-sulfur cluster assembly factor IBA57 [Source:HGNC Symbol;Acc:HGNC:27302]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006783//heme biosynthetic process;GO:0016226//iron-sulfur cluster assembly	--
ENSG00000181885	0.239	0.149	0.288	0	0.312	0	3	2	3	0	6	0	CLDN7	claudin 7 [Source:HGNC Symbol;Acc:HGNC:2049]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000181894	5.506	4.68	6.297	4.632	4.87	5.624	364	307	256	228	277	271	ZNF329	zinc finger protein 329 [Source:HGNC Symbol;Acc:HGNC:14209]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000181896	2.418	1.607	2.001	1.819	1.398	1.661	87	66	55	47	61	52	ZNF101	zinc finger protein 101 [Source:HGNC Symbol;Acc:HGNC:12881]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000181903	0	0	0	0	0	0	0	0	0	0	0	0	OR4C6	olfactory receptor family 4 subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:14743]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181904	28.129	23.177	23.634	21.27	20.448	27.736	2689	2306	1690	1583	1743	1810	C5orf24	chromosome 5 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:26746]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000181915	13.399	12.463	14.01	13.969	14.039	16.618	1045	977	807	807	925	943	ADO	2-aminoethanethiol dioxygenase [Source:HGNC Symbol;Acc:HGNC:23506]	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00430//Taurine and hypotaurine metabolism	K10712;K10712	GO:0005829//cytosol	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0047800//cysteamine dioxygenase activity;GO:0051213//dioxygenase activity"	-	--
ENSG00000181924	38.019	39.966	38.9	41.938	37.435	42.757	637	677	485	527	533	527	COA4	cytochrome c oxidase assembly factor 4 homolog [Source:HGNC Symbol;Acc:HGNC:24604]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18177	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	-	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000181927	0	0	0	0	0	0	0	0	0	0	0	0	OR4P4	olfactory receptor family 4 subfamily P member 4 [Source:HGNC Symbol;Acc:HGNC:15180]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181929	26.246	29.303	28.145	28.514	25.692	29.957	887	957	687.7	698	710.43	723	PRKAG1	protein kinase AMP-activated non-catalytic subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:9385]	Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Environmental adaptation;Cellular community - eukaryotes;Endocrine and metabolic disease;Endocrine system;Endocrine and metabolic disease;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Aging;Cardiovascular disease;Endocrine system;Aging;Environmental adaptation	ko04714//Thermogenesis;ko04530//Tight junction;ko04932//Non-alcoholic fatty liver disease;ko04921//Oxytocin signaling pathway;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04211//Longevity regulating pathway;ko05410//Hypertrophic cardiomyopathy;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04710//Circadian rhythm	K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200;K07200	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0031588//nucleotide-activated protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0016208//AMP binding;GO:0016301//kinase activity;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0032559//adenyl ribonucleotide binding;GO:0043531//ADP binding	GO:0006110//regulation of glycolytic process;GO:0006468//protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0031669//cellular response to nutrient levels;GO:0042149//cellular response to glucose starvation;GO:0045860//positive regulation of protein kinase activity;GO:0050790//regulation of catalytic activity;GO:0051170//import into nucleus;GO:0071900//regulation of protein serine/threonine kinase activity	--
ENSG00000181938	1.171	1.32	0.799	0.968	0.695	0.787	50	58	25	31	25	25	GINS3	GINS complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25851]	-	-	-	-	GO:0000811//GINS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0071162//CMG complex	GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:1900264//positive regulation of DNA-directed DNA polymerase activity;GO:1902975//mitotic DNA replication initiation;GO:1903934//positive regulation of DNA primase activity	--
ENSG00000181939	0	0	0	0	0	0	0	0	0	0	0	0	OR4C15	olfactory receptor family 4 subfamily C member 15 [Source:HGNC Symbol;Acc:HGNC:15171]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181958	0	0	0	0	0	0	0	0	0	0	0	0	OR4A15	olfactory receptor family 4 subfamily A member 15 [Source:HGNC Symbol;Acc:HGNC:15152]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181961	0	0	0	0	0	0	0	0	0	0	0	0	OR4A16	olfactory receptor family 4 subfamily A member 16 [Source:HGNC Symbol;Acc:HGNC:15153]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181963	0	0	0	0	0	0	0	0	0	0	0	0	OR52K2	olfactory receptor family 52 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:15223]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000181965	0.115	0.142	0.078	0.077	0.136	0.157	4	5	2	2	4	4	NEUROG1	neurogenin 1 [Source:HGNC Symbol;Acc:HGNC:7764]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09081	GO:0000785//chromatin;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0043204//perikaryon	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007356//thorax and anterior abdomen determination;GO:0007399//nervous system development;GO:0021559//trigeminal nerve development;GO:0021650//vestibulocochlear nerve formation;GO:0022008//neurogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030432//peristalsis;GO:0031223//auditory behavior;GO:0031536//positive regulation of exit from mitosis;GO:0035112//genitalia morphogenesis;GO:0042472//inner ear morphogenesis;GO:0045165//cell fate commitment;GO:0045664//regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048634//regulation of muscle organ development;GO:0048806//genitalia development;GO:0048839//inner ear development;GO:0050885//neuromuscular process controlling balance;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0071626//mastication;GO:0090102//cochlea development;GO:0090103//cochlea morphogenesis;GO:0097094//craniofacial suture morphogenesis;GO:0098583//learned vocalization behavior;GO:1901078//negative regulation of relaxation of muscle;GO:1905747//negative regulation of saliva secretion;GO:1905748//hard palate morphogenesis"	bHLH
ENSG00000181982	5.951	6.425	6.638	7.308	5.563	6.777	505	524	361	395	339	380	CCDC149	coiled-coil domain containing 149 [Source:HGNC Symbol;Acc:HGNC:25405]	-	-	-	-	-	-	-	--
ENSG00000181991	11.69	12.577	14.081	14.012	11.429	9.316	545	517	435	421	389	352	MRPS11	mitochondrial ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:14050]	Genetic Information Processing	Translation	ko03010//Ribosome	K02948	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding;GO:0070181//small ribosomal subunit rRNA binding	"GO:0000028//ribosomal small subunit assembly;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0032543//mitochondrial translation"	--
ENSG00000182004	18.861	14.695	13.653	11.515	19.22	17.913	314	311	241	276	231	202	SNRPE	small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K11097	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0005683//U7 snRNP;GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0034709//methylosome;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071007//U2-type catalytic step 2 spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0036261//7-methylguanosine cap hypermethylation"	--
ENSG00000182010	0.709	0.502	0.587	0.613	0.392	1.027	76	51	39	42	43	76	RTKN2	rhotekin 2 [Source:HGNC Symbol;Acc:HGNC:19364]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane	-	GO:0007165//signal transduction;GO:0008284//positive regulation of cell population proliferation;GO:0030097//hemopoiesis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000182013	33.795	30.755	31.662	28.744	31.092	24.424	2431	2356	1779	1574	1934	1355	PNMA8A	PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578]	-	-	-	-	-	-	-	--
ENSG00000182022	4.233	4.571	5.008	5.497	4.679	4.02	310	330	312	312	373	286	CHST15	carbohydrate sulfotransferase 15 [Source:HGNC Symbol;Acc:HGNC:18137]	Metabolism	Glycan biosynthesis and metabolism	ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K08106	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	GO:0019319//hexose biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000182035	0	0	0	0	0	0	0	0	0	0	0	0	ADIG	adipogenin [Source:HGNC Symbol;Acc:HGNC:28606]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0045444//fat cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0050872//white fat cell differentiation;GO:0050873//brown fat cell differentiation	--
ENSG00000182040	0.081	0.04	0.084	0.042	0.079	0.085	6	3	4	2	4	3	USH1G	USH1 protein network component sans [Source:HGNC Symbol;Acc:HGNC:16356]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body	GO:0005515//protein binding;GO:0030507//spectrin binding;GO:0042802//identical protein binding	GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis;GO:0045494//photoreceptor cell maintenance;GO:0050953//sensory perception of light stimulus;GO:0050957//equilibrioception;GO:0060113//inner ear receptor cell differentiation;GO:0060122//inner ear receptor cell stereocilium organization	--
ENSG00000182050	0.002	0.041	0.092	0	0	0.003	1.01	4	2	0	0	1	MGAT4C	MGAT4 family member C [Source:HGNC Symbol;Acc:HGNC:30871]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K13748;K13748;K13748	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0008375//acetylglucosaminyltransferase activity;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046872//metal ion binding"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0019082//viral protein processing	--
ENSG00000182053	0	0	0	0	0	0	0	0	0	0	0	0	TRIM49B	tripartite motif containing 49B [Source:HGNC Symbol;Acc:HGNC:42955]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000182054	77.394	85.487	67.113	54.629	53.251	51.459	2931	3179	1883	1521	1726	1401	IDH2	isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383]	Metabolism;Metabolism;Cellular Processes;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Transport and catabolism;Global and overview maps;Cancer: overview;Metabolism of other amino acids;Carbohydrate metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04146//Peroxisome;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00480//Glutathione metabolism;ko00020//Citrate cycle (TCA cycle);ko01210//2-Oxocarboxylic acid metabolism	K00031;K00031;K00031;K00031;K00031;K00031;K00031;K00031	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000287//magnesium ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046872//metal ion binding;GO:0051287//NAD binding"	GO:0005975//carbohydrate metabolic process;GO:0006097//glyoxylate cycle;GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006739//NADP metabolic process	--
ENSG00000182070	0	0	0	0	0	0	0	0	0	0	0	0	OR52A1	olfactory receptor family 52 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8318]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182077	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000182083	0	0	0	0	0	0	0	0	0	0	0	0	OR6B2	olfactory receptor family 6 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:15041]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182087	50.876	55.028	58.966	62.927	65.877	66.181	2537	2689	2018	2232	2641	2356	TMEM259	transmembrane protein 259 [Source:HGNC Symbol;Acc:HGNC:17039]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0034976//response to endoplasmic reticulum stress;GO:1901215//negative regulation of neuron death;GO:1904294//positive regulation of ERAD pathway	--
ENSG00000182093	32.738	31.302	34.367	29.525	27.171	32.697	1032.86	999.89	805.94	695	723.71	755.51	GET1	guided entry of tail-anchored proteins factor 1 [Source:HGNC Symbol;Acc:HGNC:12790]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043529//GET complex	GO:0005515//protein binding	GO:0045048//protein insertion into ER membrane;GO:0050821//protein stabilization;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000182095	41.873	44.577	51.631	36.897	51.141	40.153	3321	3593	2717	2364	3139	2598	TNRC18	trinucleotide repeat containing 18 [Source:HGNC Symbol;Acc:HGNC:11962]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031965//nuclear membrane	GO:0003682//chromatin binding	-	--
ENSG00000182103	0.811	0.794	0.915	0.945	1.308	0.861	66	65	55	57	90	51	FAM181B	family with sequence similarity 181 member B [Source:HGNC Symbol;Acc:HGNC:28512]	-	-	-	-	-	-	-	--
ENSG00000182107	0.279	0.218	0.049	0.197	0.216	0.117	23	18	3	12	15	7	TMEM30B	transmembrane protein 30B [Source:HGNC Symbol;Acc:HGNC:27254]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0005515//protein binding;GO:0015247//aminophospholipid flippase activity	GO:0006869//lipid transport;GO:0015917//aminophospholipid transport;GO:0045332//phospholipid translocation;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0140331//aminophospholipid translocation	--
ENSG00000182108	35.615	36.8	34.428	25.394	27.562	30.8	1270.5	1316.01	914.58	658.91	808.15	774.36	DEXI	Dexi homolog [Source:HGNC Symbol;Acc:HGNC:13267]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182111	0	0	0	0	0	0	0	0	0	0	0	0	ZNF716	zinc finger protein 716 [Source:HGNC Symbol;Acc:HGNC:32458]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000182117	32.807	29.706	31.93	36.073	28.364	36.463	345	314	248	281	252	279	NOP10	NOP10 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14378]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K11130	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005732//sno(s)RNA-containing ribonucleoprotein complex;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0031429//box H/ACA snoRNP complex;GO:0072589//box H/ACA scaRNP complex;GO:0090661//box H/ACA telomerase RNP complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding	GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing;GO:0007004//telomere maintenance via telomerase;GO:0031118//rRNA pseudouridine synthesis;GO:0031120//snRNA pseudouridine synthesis;GO:0042254//ribosome biogenesis;GO:1904874//positive regulation of telomerase RNA localization to Cajal body	--
ENSG00000182118	6.48	6.255	8.686	9.18	9.758	11.991	202	196	200	212	257	272	FAM89A	family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057]	-	-	-	-	-	-	-	--
ENSG00000182132	0.288	0.248	0.65	1.262	1.103	1.256	11	9	16	33	37	29	KCNIP1	potassium voltage-gated channel interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15521]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000182134	4.257	4.52	3.684	3.536	4.714	4.735	236	244	148	144	215	192	TDRKH	tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043186//P granule;GO:0043229//intracellular organelle;GO:0071546//pi-body;GO:0071547//piP-body	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation	--
ENSG00000182141	3.447	5.607	3.565	2.481	4.038	3.059	252	263	184	137.49	199.56	148	ZNF708	zinc finger protein 708 [Source:HGNC Symbol;Acc:HGNC:12945]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000182149	70.796	65.368	73.823	82.337	76.119	83.665	2139	2109	1725	1740	1942	1731	IST1	IST1 factor associated with ESCRT-III [Source:HGNC Symbol;Acc:HGNC:28977]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K19476	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0090543//Flemming body	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0090541//MIT domain binding	GO:0007049//cell cycle;GO:0008104//protein localization;GO:0009838//abscission;GO:0015031//protein transport;GO:0019076//viral release from host cell;GO:0036258//multivesicular body assembly;GO:0045184//establishment of protein localization;GO:0045862//positive regulation of proteolysis;GO:0046745//viral capsid secondary envelopment;GO:0048672//positive regulation of collateral sprouting;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis;GO:1904903//ESCRT III complex disassembly	--
ENSG00000182150	3.299	2.292	2.388	2.203	2.136	1.822	408	281	231	174	219.01	159	ERCC6L2	ERCC excision repair 6 like 2 [Source:HGNC Symbol;Acc:HGNC:26922]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006281//DNA repair;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0034614//cellular response to reactive oxygen species;GO:0036297//interstrand cross-link repair	--
ENSG00000182154	39.348	43.514	43.406	55.692	52.162	55.445	475	528	387	498	532	487	MRPL41	mitochondrial ribosomal protein L41 [Source:HGNC Symbol;Acc:HGNC:14492]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0032543//mitochondrial translation	--
ENSG00000182156	0	0	0	0	0	0	0	0	0	0	0	0	ENPP7	ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:HGNC Symbol;Acc:HGNC:23764]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism	K12354;K12354	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0006685//sphingomyelin catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell population proliferation;GO:0044241//lipid digestion;GO:0045797//positive regulation of intestinal cholesterol absorption;GO:0055089//fatty acid homeostasis;GO:1904729//regulation of intestinal lipid absorption;GO:2000304//positive regulation of ceramide biosynthetic process;GO:2000755//positive regulation of sphingomyelin catabolic process	--
ENSG00000182158	10.349	10.145	9.215	7.531	9.018	7.409	1581	1518	1042	861	1160	832	CREB3L2	cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Cancer: specific types;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence;Excretory system	"ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05020//Prion disease;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04916//Melanogenesis;ko05215//Prostate cancer;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction;ko04962//Vasopressin-regulated water reabsorption"	K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048;K09048	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097038//perinuclear endoplasmic reticulum	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0035497//cAMP response element binding"	"GO:0002062//chondrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006986//response to unfolded protein;GO:0009611//response to wounding;GO:0010628//positive regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034976//response to endoplasmic reticulum stress;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051216//cartilage development"	TF_bZIP
ENSG00000182162	0	0	0	0	0.013	0	0	0	0	0	1	0	P2RY8	P2Y receptor family member 8 [Source:HGNC Symbol;Acc:HGNC:15524]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K08386	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0045028//G protein-coupled purinergic nucleotide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000182168	0.512	0.644	0.508	0.408	0.527	0.38	84	79	68	59	66	44	UNC5C	unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07521	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0005042//netrin receptor activity;GO:0005043//netrin receptor activity involved in chemorepulsion;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019901//protein kinase binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0007420//brain development;GO:0030334//regulation of cell migration;GO:0033564//anterior/posterior axon guidance;GO:0038007//netrin-activated signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0061643//chemorepulsion of axon;GO:1990791//dorsal root ganglion development	--
ENSG00000182170	0	0	0	0	0	0	0	0	0	0	0	0	MRGPRG	MAS related GPR family member G [Source:HGNC Symbol;Acc:HGNC:24829]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000182173	4.127	4.501	4.211	4.872	5.011	5.143	175	186	136.13	148	170	158.1	TSEN54	tRNA splicing endonuclease subunit 54 [Source:HGNC Symbol;Acc:HGNC:27561]	-	-	-	-	GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	"GO:0000379//tRNA-type intron splice site recognition and cleavage;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0008033//tRNA processing"	--
ENSG00000182175	20.597	20.814	19.784	19.792	19.719	19.425	1308	1394	927	925	1057	890	RGMA	repulsive guidance molecule BMP co-receptor a [Source:HGNC Symbol;Acc:HGNC:30308]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signal transduction	ko04360//Axon guidance;ko04350//TGF-beta signaling pathway	K23096;K23096	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:1990459//transferrin receptor binding	GO:0001843//neural tube closure;GO:0010975//regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0030509//BMP signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0031175//neuron projection development;GO:0043547//positive regulation of GTPase activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048681//negative regulation of axon regeneration;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:1900121//negative regulation of receptor binding	--
ENSG00000182177	0	0	0	0	0	0	0	0	0	0	0	0	ASB18	ankyrin repeat and SOCS box containing 18 [Source:HGNC Symbol;Acc:HGNC:19770]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000182179	4.319	4.689	5.157	2.108	3.282	2.808	296	323	261	107	190	140	UBA7	ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K10698;K10698;K10698	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0016874//ligase activity;GO:0019782//ISG15 activating enzyme activity	GO:0006464//cellular protein modification process;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0032020//ISG15-protein conjugation;GO:0032446//protein modification by small protein conjugation	--
ENSG00000182180	26.63	27.946	24.874	27.867	27.601	30.543	1175	1172	827	910	1036	952	MRPS16	mitochondrial ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:14048]	Genetic Information Processing	Translation	ko03010//Ribosome	K02959	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000182183	0	0.156	0	0	0	0	0	3	0	0	0	0	SHISAL2A	shisa like 2A [Source:HGNC Symbol;Acc:HGNC:28757]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000182185	1.174	1.502	1.391	1.203	1.363	0.932	44	53	37	28	35	26	RAD51B	RAD51 paralog B [Source:HGNC Symbol;Acc:HGNC:9822]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10869	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex	"GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA"	GO:0000724//double-strand break repair via homologous recombination;GO:0001701//in utero embryonic development;GO:0001832//blastocyst growth;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007131//reciprocal meiotic recombination;GO:0008284//positive regulation of cell population proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0061053//somite development	--
ENSG00000182187	0	0	0	0	0	0	0	0	0	0	0	0	CRYGB	crystallin gamma B [Source:HGNC Symbol;Acc:HGNC:2409]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005212//structural constituent of eye lens	GO:0001654//eye development;GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0070307//lens fiber cell development;GO:0070309//lens fiber cell morphogenesis	--
ENSG00000182195	10.707	10.64	10.257	11.814	12.014	10.156	865	864	612	707	820	597	LDOC1	LDOC1 regulator of NFKB signaling [Source:HGNC Symbol;Acc:HGNC:6548]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0001893//maternal placenta development;GO:0008285//negative regulation of cell population proliferation;GO:0060137//maternal process involved in parturition;GO:0071222//cellular response to lipopolysaccharide;GO:0071225//cellular response to muramyl dipeptide;GO:1903547//regulation of growth hormone activity	--
ENSG00000182196	52.983	55.805	58.12	68.814	61.136	61.27	1036.26	1130.91	841.5	995.82	1009.21	877.59	ARL6IP4	ADP ribosylation factor like GTPase 6 interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:18076]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000182197	21.503	25.273	17.007	24.239	26.537	23.911	1902	1959	1179	1502	1856	1472	EXT1	exostosin glycosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3512]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02366;K02366	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0045202//synapse	GO:0008375//acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	"GO:0000902//cell morphogenesis;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001958//endochondral ossification;GO:0001974//blood vessel remodeling;GO:0002062//chondrocyte differentiation;GO:0002067//glandular epithelial cell differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002524//hypersensitivity;GO:0003128//heart field specification;GO:0003415//chondrocyte hypertrophy;GO:0003416//endochondral bone growth;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0007033//vacuole organization;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007369//gastrulation;GO:0007411//axon guidance;GO:0007420//brain development;GO:0007492//endoderm development;GO:0007498//mesoderm development;GO:0008217//regulation of blood pressure;GO:0008283//cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009615//response to virus;GO:0009642//response to light intensity;GO:0010467//gene expression;GO:0014033//neural crest cell differentiation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0016043//cellular component organization;GO:0017145//stem cell division;GO:0019882//antigen processing and presentation;GO:0021554//optic nerve development;GO:0021772//olfactory bulb development;GO:0022405//hair cycle process;GO:0030163//protein catabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0030199//collagen fibril organization;GO:0030202//heparin metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030210//heparin biosynthetic process;GO:0030509//BMP signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0031175//neuron projection development;GO:0032836//glomerular basement membrane development;GO:0033627//cell adhesion mediated by integrin;GO:0033692//cellular polysaccharide biosynthetic process;GO:0035176//social behavior;GO:0035249//synaptic transmission, glutamatergic;GO:0035264//multicellular organism growth;GO:0035988//chondrocyte proliferation;GO:0036022//limb joint morphogenesis;GO:0036336//dendritic cell migration;GO:0036339//lymphocyte adhesion to endothelial cell of high endothelial venule;GO:0042044//fluid transport;GO:0042060//wound healing;GO:0042311//vasodilation;GO:0042596//fear response;GO:0043931//ossification involved in bone maturation;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045165//cell fate commitment;GO:0045453//bone resorption;GO:0048598//embryonic morphogenesis;GO:0048733//sebaceous gland development;GO:0050891//multicellular organismal water homeostasis;GO:0050901//leukocyte tethering or rolling;GO:0051923//sulfation;GO:0055078//sodium ion homeostasis;GO:0060047//heart contraction;GO:0060070//canonical Wnt signaling pathway;GO:0060218//hematopoietic stem cell differentiation;GO:0060349//bone morphogenesis;GO:0060350//endochondral bone morphogenesis;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0060429//epithelium development;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060485//mesenchyme development;GO:0060506//smoothened signaling pathway involved in lung development;GO:0060560//developmental growth involved in morphogenesis;GO:0060792//sweat gland development;GO:0061484//hematopoietic stem cell homeostasis;GO:0061744//motor behavior;GO:0061974//perichondral bone morphogenesis;GO:0062094//stomach development;GO:0065003//protein-containing complex assembly;GO:0070593//dendrite self-avoidance;GO:0070848//response to growth factor;GO:0071503//response to heparin;GO:0071625//vocalization behavior;GO:0071711//basement membrane organization;GO:0071773//cellular response to BMP stimulus;GO:0071847//TNFSF11-mediated signaling pathway;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072498//embryonic skeletal joint development;GO:0097021//lymphocyte migration into lymphoid organs;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0098586//cellular response to virus;GO:0098868//bone growth;GO:0120193//tight junction organization;GO:1901706//mesenchymal cell differentiation involved in bone development;GO:1904888//cranial skeletal system development;GO:1990823//response to leukemia inhibitory factor"	--
ENSG00000182199	33.807	31.261	33.547	36.22	34.716	51.384	1456	1350	1007	1176	1238	1568	SHMT2	serine hydroxymethyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10852]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Human Diseases;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko01523//Antifolate resistance;ko00670//One carbon pool by folate"	K00600;K00600;K00600;K00600;K00600;K00600;K00600	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular exosome;GO:0070552//BRISC complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003682//chromatin binding;GO:0003824//catalytic activity;GO:0004372//glycine hydroxymethyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0048027//mRNA 5'-UTR binding;GO:0070905//serine binding"	GO:0002082//regulation of oxidative phosphorylation;GO:0006544//glycine metabolic process;GO:0006563//L-serine metabolic process;GO:0006565//L-serine catabolic process;GO:0006730//one-carbon metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0017148//negative regulation of translation;GO:0019264//glycine biosynthetic process from serine;GO:0032259//methylation;GO:0034340//response to type I interferon;GO:0035999//tetrahydrofolate interconversion;GO:0046653//tetrahydrofolate metabolic process;GO:0046655//folic acid metabolic process;GO:0051262//protein tetramerization;GO:0051289//protein homotetramerization;GO:0070129//regulation of mitochondrial translation;GO:0070536//protein K63-linked deubiquitination;GO:1903715//regulation of aerobic respiration	--
ENSG00000182208	4.586	4.068	5.237	6.005	5.527	5.81	166	148	140	161	169	153	MOB2	MOB kinase activator 2 [Source:HGNC Symbol;Acc:HGNC:24904]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0046872//metal ion binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity	--
ENSG00000182218	4.265	4.562	4.18	4.035	4.378	3.668	635	701	472	457	544	408	HHIPL1	HHIP like 1 [Source:HGNC Symbol;Acc:HGNC:19710]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0016020//membrane	GO:0003674//molecular_function;GO:0003824//catalytic activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0008150//biological_process	--
ENSG00000182220	74.525	74.783	80.622	69.393	73.046	68.568	3063	3086	2162	2025	2285	2119	ATP6AP2	ATPase H+ transporting accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:18305]	Organismal Systems	Endocrine system	ko04614//Renin-angiotensin system	K19514	"GO:0000139//Golgi membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0000421//autophagosome membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030054//cell junction;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0032591//dendritic spine membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane"	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002003//angiotensin maturation;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0021626//central nervous system maturation;GO:0021903//rostrocaudal neural tube patterning;GO:0030177//positive regulation of Wnt signaling pathway;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0043408//regulation of MAPK cascade;GO:0048069//eye pigmentation;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0060323//head morphogenesis;GO:0061795//Golgi lumen acidification;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902600//proton transmembrane transport	--
ENSG00000182223	0	0	0	0	0	0	0	0	0	0	0	0	ZAR1	zygote arrest 1 [Source:HGNC Symbol;Acc:HGNC:20436]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:1903231//mRNA binding involved in posttranscriptional gene silencing	GO:0006412//translation;GO:0016441//posttranscriptional gene silencing	--
ENSG00000182224	6.566	7.422	6.447	6.276	5.898	7.166	428	494	310	311	342	334	CYB5D1	cytochrome b5 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26516]	-	-	-	-	-	GO:0046872//metal ion binding	-	--
ENSG00000182230	0.044	0	0	0	0	0	1.5	0	0	0	0	0	FAM153B	family with sequence similarity 153 member B [Source:HGNC Symbol;Acc:HGNC:27323]	-	-	-	-	-	-	-	--
ENSG00000182240	57.739	61.724	56.288	56.479	52.557	48.845	5368	5679	3789	3671	4139	3233	BACE2	beta-secretase 2 [Source:HGNC Symbol;Acc:HGNC:934]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K07747	GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0016486//peptide hormone processing;GO:0042593//glucose homeostasis;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0050435//amyloid-beta metabolic process	--
ENSG00000182247	27.627	26.84	28.321	22.949	22.313	27.018	762	732	559	462	504	536	UBE2E2	ubiquitin conjugating enzyme E2 E2 [Source:HGNC Symbol;Acc:HGNC:12478]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K20217	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0042296//ISG15 transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0032446//protein modification by small protein conjugation;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle	--
ENSG00000182253	21.244	19.827	25.877	20.856	21.616	25.584	3127	2923	2777	2270	2670	2769	SYNM	synemin [Source:HGNC Symbol;Acc:HGNC:24466]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0042383//sarcolemma;GO:0043034//costamere;GO:0045111//intermediate filament cytoskeleton;GO:0060053//neurofilament cytoskeleton	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0017166//vinculin binding;GO:0019215//intermediate filament binding	GO:0031443//fast-twitch skeletal muscle fiber contraction;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000182255	0.081	0.069	0.078	0.217	0.191	0.19	7	6	5	14	14	12	KCNA4	potassium voltage-gated channel subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:6222]	Human Diseases;Organismal Systems	Endocrine and metabolic disease;Endocrine system	ko04934//Cushing syndrome;ko04927//Cortisol synthesis and secretion	K04877;K04877	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043194//axon initial segment;GO:0043197//dendritic spine	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0030955//potassium ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000182256	0.326	0.414	0.107	0.375	0.552	0.212	13	19	5	12	25	13	GABRG3	gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05186;K05186;K05186;K05186;K05186	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032590//dendrite membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:0099699//integral component of synaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0009410//response to xenobiotic stimulus;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport"	--
ENSG00000182261	0.011	0.011	0.031	0.123	0	0	1	1	2	8	0	0	NLRP10	NLR family pyrin domain containing 10 [Source:HGNC Symbol;Acc:HGNC:21464]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019897//extrinsic component of plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006954//inflammatory response;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0050832//defense response to fungus;GO:1900426//positive regulation of defense response to bacterium;GO:2000318//positive regulation of T-helper 17 type immune response	--
ENSG00000182263	1.254	0.895	0.945	0.669	0.616	0.987	248	178	138	98	103	142	FIGN	"fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016363//nuclear matrix	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008568//microtubule-severing ATPase activity;GO:0016887//ATP hydrolysis activity	GO:0007049//cell cycle;GO:0051013//microtubule severing;GO:0051301//cell division	--
ENSG00000182264	0	0	0	0	0	0	0	0	0	0	0	0	IZUMO1	izumo sperm-egg fusion 1 [Source:HGNC Symbol;Acc:HGNC:28539]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0086080//protein binding involved in heterotypic cell-cell adhesion	GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0034113//heterotypic cell-cell adhesion;GO:0035036//sperm-egg recognition	--
ENSG00000182271	0	0	0	0	0	0	0	0	0	0	0	0	TMIGD1	transmembrane and immunoglobulin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:32431]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	-	GO:0030334//regulation of cell migration;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0090559//regulation of membrane permeability	--
ENSG00000182272	6.66	6.888	6.858	5.814	5.904	5.813	518	530	394	335	388	329	B4GALNT4	"beta-1,4-N-acetyl-galactosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:26315]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00513//Various types of N-glycan biosynthesis	K09657;K09657	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	-	--
ENSG00000182287	163.184	135.222	155.362	145.281	128.107	166.713	7777.52	6266.63	5409.82	5122.05	5100.36	5564.7	AP1S2	adaptor related protein complex 1 subunit sigma 2 [Source:HGNC Symbol;Acc:HGNC:560]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12394;K12394	GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030119//AP-type membrane coat adaptor complex;GO:0030121//AP-1 adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly	--
ENSG00000182307	23.286	24.709	25.122	23.665	23.703	24.22	1250	1331	996	941	1075	946	C8orf33	chromosome 8 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:26104]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182308	0.02	0	0	0	0	0.014	2	0	0	0	0	1	DCAF4L1	DDB1 and CUL4 associated factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:27723]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182310	0.506	0.194	0.369	0.42	0.461	0.749	13	5	7	8	10	14	SPACA6	sperm acrosome associated 6 [Source:HGNC Symbol;Acc:HGNC:27113]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization	--
ENSG00000182315	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L3	methyl-CpG binding domain protein 3 like 3 [Source:HGNC Symbol;Acc:HGNC:37205]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182318	1.026	0.804	0.884	0.881	0.785	1.182	99	78.03	63	63	64	83	ZSCAN22	zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000182324	0.085	0.137	0.102	0.068	0.104	0.12	7	11	6	4	7	7	KCNJ14	potassium inwardly rectifying channel subfamily J member 14 [Source:HGNC Symbol;Acc:HGNC:6260]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04921//Oxytocin signaling pathway;ko04725//Cholinergic synapse	K05007;K05007	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000182325	1.881	1.677	2.282	2.835	2.191	2.586	68	61	61	76	67	68	FBXL6	F-box and leucine rich repeat protein 6 [Source:HGNC Symbol;Acc:HGNC:13603]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006508//proteolysis;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0051726//regulation of cell cycle	--
ENSG00000182326	338.66	368.185	367.635	355.239	367.58	394.602	20063	22046	16109	15600	18439	17076	C1S	complement C1s [Source:HGNC Symbol;Acc:HGNC:1247]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K01331;K01331;K01331;K01331;K01331	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response"	--
ENSG00000182327	0.079	0.039	0.161	0.481	0.516	0.163	2	1	3	9	11	3	GLTPD2	glycolipid transfer protein domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33756]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0120013//lipid transfer activity;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0035627//ceramide transport;GO:0120009//intermembrane lipid transfer;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000182329	0	0	0	0	0	0	0	0	0	0	0	0	KIAA2012	KIAA2012 [Source:HGNC Symbol;Acc:HGNC:51250]	-	-	-	-	-	-	-	--
ENSG00000182330	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF8	PRAME family member 8 [Source:HGNC Symbol;Acc:HGNC:24074]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000182333	0	0	0.051	0	0	0	0	0	1	0	0	0	LIPF	"lipase F, gastric type [Source:HGNC Symbol;Acc:HGNC:6622]"	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K14452;K14452;K14452	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	"GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0016615//malate dehydrogenase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006108//malate metabolic process;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0016042//lipid catabolic process	--
ENSG00000182334	0	0	0	0	0	0	0	0	0	0	0	0	OR5P3	olfactory receptor family 5 subfamily P member 3 [Source:HGNC Symbol;Acc:HGNC:14784]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182346	0	0	0	0	0	0	0	0	0	0	0	0	DAOA	D-amino acid oxidase activator [Source:HGNC Symbol;Acc:HGNC:21191]	-	-	-	-	GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm	GO:0008047//enzyme activator activity;GO:0019899//enzyme binding	GO:0043085//positive regulation of catalytic activity;GO:1900758//negative regulation of D-amino-acid oxidase activity	--
ENSG00000182348	0	0	0	0	0	0	0	0	0	0	0	0	ZNF804B	zinc finger protein 804B [Source:HGNC Symbol;Acc:HGNC:21958]	-	-	-	-	GO:0005634//nucleus	GO:0046872//metal ion binding	-	--
ENSG00000182359	1.689	1.324	1.64	1.092	1.206	1.42	134	106	96	64	81	82	KBTBD3	kelch repeat and BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22934]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182362	5.401	5.935	5.535	6.716	4.155	5.987	87	98	69	79	56	71	YBEY	ybeY metalloendoribonuclease [Source:HGNC Symbol;Acc:HGNC:1299]	-	-	-	-	GO:0005634//nucleus	GO:0004222//metalloendopeptidase activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0006364//rRNA processing;GO:0006508//proteolysis;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000182372	5.686	5.582	6.451	5.777	7.299	7.134	619.22	599.91	489	522.9	635.89	533.96	CLN8	CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0098793//presynapse	GO:0005515//protein binding;GO:0097001//ceramide binding	GO:0006644//phospholipid metabolic process;GO:0006672//ceramide metabolic process;GO:0006869//lipid transport;GO:0007399//nervous system development;GO:0008203//cholesterol metabolic process;GO:0008610//lipid biosynthetic process;GO:0030163//protein catabolic process;GO:0045861//negative regulation of proteolysis;GO:0046513//ceramide biosynthetic process;GO:0055088//lipid homeostasis	--
ENSG00000182378	3.99	5.108	5.168	8	5.634	6.665	239	212	197	249	223	208	PLCXD1	phosphatidylinositol specific phospholipase C X domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23148]	-	-	-	-	GO:0005737//cytoplasm	GO:0008081//phosphoric diester hydrolase activity	GO:0006629//lipid metabolic process	--
ENSG00000182379	0.401	0.478	0.253	0.18	0.221	0.073	15	18	7	5	7	2	NXPH4	neurexophilin 4 [Source:HGNC Symbol;Acc:HGNC:8078]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005102//signaling receptor binding	GO:0007218//neuropeptide signaling pathway	--
ENSG00000182389	0.752	0.536	0.493	0.859	0.429	0.518	64	56	39	37	38	22	CACNB4	calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04865;K04865;K04865;K04865;K04865;K04865;K04865	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0045202//synapse	GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008331//high voltage-gated calcium channel activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:1901385//regulation of voltage-gated calcium channel activity	--
ENSG00000182393	0	0	0	0	0	0	0	0	0	0	0	0	IFNL1	interferon lambda 1 [Source:HGNC Symbol;Acc:HGNC:18363]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05447;K05447	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0032002//interleukin-28 receptor complex	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0032003//interleukin-28 receptor binding	"GO:0002829//negative regulation of type 2 immune response;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0008285//negative regulation of cell population proliferation;GO:0032696//negative regulation of interleukin-13 production;GO:0032714//negative regulation of interleukin-5 production;GO:0032729//positive regulation of interferon-gamma production;GO:0038196//type III interferon signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043381//negative regulation of memory T cell differentiation;GO:0045087//innate immune response;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045581//negative regulation of T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus;GO:0098586//cellular response to virus"	--
ENSG00000182400	7.46	6.208	8.494	7.597	8.067	6.937	394	333	269	252	292	300	TRAPPC6B	trafficking protein particle complex subunit 6B [Source:HGNC Symbol;Acc:HGNC:23066]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:1990071//TRAPPII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0007399//nervous system development;GO:0043087//regulation of GTPase activity;GO:0048193//Golgi vesicle transport;GO:0099022//vesicle tethering	--
ENSG00000182405	0.511	0.421	0.494	0.404	0.665	0.472	70	58	50	41	77	47	PGBD4	piggyBac transposable element derived 4 [Source:HGNC Symbol;Acc:HGNC:19401]	-	-	-	-	-	-	-	--
ENSG00000182415	0	0	0.033	0	0	0	0	0	1	0	0	0	CDY2A	chromodomain Y-linked 2A [Source:HGNC Symbol;Acc:HGNC:1810]	-	-	-	-	GO:0005634//nucleus	GO:0003714//transcription corepressor activity;GO:0003824//catalytic activity;GO:0004402//histone acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	"GO:0007283//spermatogenesis;GO:0016573//histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000182446	48.597	48.371	52.351	48.416	48.012	50.298	4417	4343	3329	3200	3607	3217	NPLOC4	"NPL4 homolog, ubiquitin recognition factor [Source:HGNC Symbol;Acc:HGNC:18261]"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14015	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0036501//UFD1-NPL4 complex;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051117//ATPase binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007030//Golgi organization;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0030970//retrograde protein transport, ER to cytosol;GO:0032480//negative regulation of type I interferon production;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process"	--
ENSG00000182447	0	0	0	0	0	0	0	0	0	0	0	0	OTOL1	otolin 1 [Source:HGNC Symbol;Acc:HGNC:34071]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0030198//extracellular matrix organization;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0045299//otolith mineralization;GO:0051260//protein homooligomerization	--
ENSG00000182450	0	0.035	0	0	0	0	0	1	0	0	0	0	KCNK4	potassium two pore domain channel subfamily K member 4 [Source:HGNC Symbol;Acc:HGNC:6279]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034705//potassium channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity;GO:0097604//temperature-gated cation channel activity;GO:0098782//mechanosensitived potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007613//memory;GO:0019233//sensory perception of pain;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0050951//sensory perception of temperature stimulus;GO:0050976//detection of mechanical stimulus involved in sensory perception of touch;GO:0071260//cellular response to mechanical stimulus;GO:0071398//cellular response to fatty acid;GO:0071469//cellular response to alkaline pH;GO:0071502//cellular response to temperature stimulus;GO:0071805//potassium ion transmembrane transport	--
ENSG00000182459	0	0	0.034	0	0	0	0	0	1	0	0	0	TEX19	testis expressed 19 [Source:HGNC Symbol;Acc:HGNC:33802]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0034584//piRNA binding	GO:0001890//placenta development;GO:0007131//reciprocal meiotic recombination;GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0051321//meiotic cell cycle	--
ENSG00000182463	4.154	5.899	4.856	5.224	5.388	7.793	571	550	404	379	525	390	TSHZ2	teashirt zinc finger homeobox 2 [Source:HGNC Symbol;Acc:HGNC:13010]	Environmental Information Processing	Signal transduction	ko04391//Hippo signaling pathway - fly	K09236	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression	zf-C2H2
ENSG00000182472	0.04	0	0	0.245	0.072	0.075	2	0	0	4.05	3	1.01	CAPN12	calpain 12 [Source:HGNC Symbol;Acc:HGNC:13249]	-	-	-	-	GO:0005737//cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000182473	44.322	46.824	44.873	43.574	46.255	41.227	3609	3758	2742	2665	3212	2552	EXOC7	exocyst complex component 7 [Source:HGNC Symbol;Acc:HGNC:23214]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05132//Salmonella infection;ko04910//Insulin signaling pathway	K07195;K07195	GO:0000145//exocyst;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032584//growth cone membrane;GO:0034451//centriolar satellite;GO:0090543//Flemming body	GO:0005515//protein binding	GO:0000281//mitotic cytokinesis;GO:0006887//exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0016241//regulation of macroautophagy;GO:0090148//membrane fission;GO:0090522//vesicle tethering involved in exocytosis;GO:2000535//regulation of entry of bacterium into host cell	--
ENSG00000182477	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000182481	26.043	25.453	26.306	26.313	24.207	26.091	1055	1050	795	800	838	779	KPNA2	karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Infectious disease: viral;Translation	ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K15043;K15043;K15043	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0042564//NLS-dependent protein nuclear import complex;GO:0043657//host cell;GO:0098892//extrinsic component of postsynaptic specialization membrane;GO:0098978//glutamatergic synapse	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0042826//histone deacetylase binding;GO:0061608//nuclear import signal receptor activity	GO:0000018//regulation of DNA recombination;GO:0006259//DNA metabolic process;GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0015031//protein transport;GO:0016032//viral process;GO:0075506//entry of viral genome into host nucleus through nuclear pore complex via importin;GO:0099527//postsynapse to nucleus signaling pathway;GO:1903902//positive regulation of viral life cycle	--
ENSG00000182484	15.8	12.718	16.07	17.807	14.237	18.28	470.94	381.01	353.77	393.14	358.51	396.45	WASH6P	"WASP family homolog 6, pseudogene [Source:HGNC Symbol;Acc:HGNC:31685]"	Cellular Processes;Organismal Systems	Transport and catabolism;Aging	ko04144//Endocytosis;ko04212//Longevity regulating pathway - worm	K18461;K18461	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0031901//early endosome membrane;GO:0055038//recycling endosome membrane;GO:0071203//WASH complex	GO:0003779//actin binding;GO:0043014//alpha-tubulin binding	GO:0034314//Arp2/3 complex-mediated actin nucleation	--
ENSG00000182489	0	0	0	0	0	0	0	0	0	0	0	0	XKRX	XK related X-linked [Source:HGNC Symbol;Acc:HGNC:29845]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000182492	112.122	125.753	62.994	10.926	17.51	16.667	5389	6017	2214	395	722	579	BGN	biglycan [Source:HGNC Symbol;Acc:HGNC:1044]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0031012//extracellular matrix;GO:0042383//sarcolemma;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0050840//extracellular matrix binding	GO:0008150//biological_process;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0060348//bone development;GO:0061975//articular cartilage development	--
ENSG00000182504	2.62	2.106	2.028	1.548	1.765	2.179	380	271	203	151	188	217.23	CEP97	centrosomal protein 97 [Source:HGNC Symbol;Acc:HGNC:26244]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0030030//cell projection organization;GO:1901673//regulation of mitotic spindle assembly;GO:1902018//negative regulation of cilium assembly	--
ENSG00000182508	0.062	0	0.084	0.125	0.073	0.128	2	0	2	3	2	3	LHFPL1	LHFPL tetraspan subfamily member 1 [Source:HGNC Symbol;Acc:HGNC:6587]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000182511	0.583	0.607	0.319	1.786	1.278	1.148	31	24	13	31	37	24	FES	"FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657]"	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07527	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0034987//immunoglobulin receptor binding;GO:0035091//phosphatidylinositol binding	GO:0001578//microtubule bundle formation;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0007098//centrosome cycle;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008360//regulation of cell shape;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0031116//positive regulation of microtubule polymerization;GO:0042127//regulation of cell population proliferation;GO:0043304//regulation of mast cell degranulation;GO:0045087//innate immune response;GO:0045595//regulation of cell differentiation;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0046777//protein autophosphorylation;GO:0060627//regulation of vesicle-mediated transport;GO:0071305//cellular response to vitamin D;GO:2000145//regulation of cell motility;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000182512	36.978	35.595	40.158	46.735	42.244	36.104	846	820	680	792	817	601	GLRX5	glutaredoxin 5 [Source:HGNC Symbol;Acc:HGNC:20134]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:1990229//iron-sulfur cluster assembly complex	"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0097573//glutathione oxidoreductase activity"	GO:0016226//iron-sulfur cluster assembly;GO:0030097//hemopoiesis;GO:0044571//[2Fe-2S] cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis;GO:0106034//protein maturation by [2Fe-2S] cluster transfer;GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000182518	7.724	6.959	6.055	8.272	6.116	6.607	235	244	155	199	185	160	FAM104B	family with sequence similarity 104 member B [Source:HGNC Symbol;Acc:HGNC:25085]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182521	0	0	0	0	0	0	0	0	0	0	0	0	TBPL2	TATA-box binding protein like 2 [Source:HGNC Symbol;Acc:HGNC:19841]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Transcription	ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05017//Spinocerebellar ataxia;ko03022//Basal transcription factors	K03120;K03120;K03120;K03120;K03120;K03120	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0140223//general transcription initiation factor activity	"GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000182533	0	0	0	0	0	0	0	0	0	0	0	0	CAV3	caveolin 3 [Source:HGNC Symbol;Acc:HGNC:1529]	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Neurodegenerative disease;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cardiovascular disease;Infectious disease: bacterial	ko05020//Prion disease;ko04144//Endocytosis;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05418//Fluid shear stress and atherosclerosis;ko05100//Bacterial invasion of epithelial cells	K12959;K12959;K12959;K12959;K12959;K12959	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016020//membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031594//neuromuscular junction;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0017080//sodium channel regulator activity;GO:0019870//potassium channel inhibitor activity;GO:0019899//enzyme binding;GO:0043014//alpha-tubulin binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0050998//nitric-oxide synthase binding;GO:0060090//molecular adaptor activity;GO:0071253//connexin binding	GO:0001666//response to hypoxia;GO:0001778//plasma membrane repair;GO:0002027//regulation of heart rate;GO:0002931//response to ischemia;GO:0006469//negative regulation of protein kinase activity;GO:0006641//triglyceride metabolic process;GO:0006897//endocytosis;GO:0007009//plasma membrane organization;GO:0007015//actin filament organization;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007517//muscle organ development;GO:0007520//myoblast fusion;GO:0008016//regulation of heart contraction;GO:0008104//protein localization;GO:0008284//positive regulation of cell population proliferation;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0010831//positive regulation of myotube differentiation;GO:0014819//regulation of skeletal muscle contraction;GO:0014902//myotube differentiation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0023051//regulation of signaling;GO:0030154//cell differentiation;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031579//membrane raft organization;GO:0033292//T-tubule organization;GO:0035995//detection of muscle stretch;GO:0038009//regulation of signal transduction by receptor internalization;GO:0042391//regulation of membrane potential;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0043407//negative regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0045792//negative regulation of cell size;GO:0046716//muscle cell cellular homeostasis;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051394//regulation of nerve growth factor receptor activity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051647//nucleus localization;GO:0051896//regulation of protein kinase B signaling;GO:0051924//regulation of calcium ion transport;GO:0051926//negative regulation of calcium ion transport;GO:0055013//cardiac muscle cell development;GO:0055117//regulation of cardiac muscle contraction;GO:0060299//negative regulation of sarcomere organization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060347//heart trabecula formation;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0070836//caveola assembly;GO:0071417//cellular response to organonitrogen compound;GO:0072659//protein localization to plasma membrane;GO:0086005//ventricular cardiac muscle cell action potential;GO:0090279//regulation of calcium ion import;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:1900744//regulation of p38MAPK cascade;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:1900826//negative regulation of membrane depolarization during cardiac muscle cell action potential;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:2000009//negative regulation of protein localization to cell surface;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:2001288//positive regulation of caveolin-mediated endocytosis	--
ENSG00000182534	208.843	228.475	230.724	236.017	236.575	229.035	8847	9725	7303	7394	8465	7160	MXRA7	matrix remodeling associated 7 [Source:HGNC Symbol;Acc:HGNC:7541]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	-	-	--
ENSG00000182541	60.518	66.154	48.764	51.455	52.052	49.636	3287	3484	2016	1966	2396	2017	LIMK2	LIM domain kinase 2 [Source:HGNC Symbol;Acc:HGNC:6614]	Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems	Cell motility;Infectious disease: viral;Development and regeneration;Immune system	ko04810//Regulation of actin cytoskeleton;ko05170//Human immunodeficiency virus 1 infection;ko04360//Axon guidance;ko04666//Fc gamma R-mediated phagocytosis	K05744;K05744;K05744;K05744	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005801//cis-Golgi network;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0043229//intracellular organelle;GO:0048471//perinuclear region of cytoplasm;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030953//astral microtubule organization;GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0051650//establishment of vesicle localization;GO:0060322//head development;GO:0061303//cornea development in camera-type eye;GO:1900182//positive regulation of protein localization to nucleus;GO:1902018//negative regulation of cilium assembly	--
ENSG00000182544	22.943	25.018	24.831	29.023	27.608	34.138	833	942	676	797	828	890	MFSD5	major facilitator superfamily domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28156]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015098//molybdate ion transmembrane transporter activity	GO:0006811//ion transport;GO:0015689//molybdate ion transport	--
ENSG00000182545	0.099	0.112	0.033	0.1	0.088	0.07	8	9.08	2	6	6.01	4.1	RNASE10	ribonuclease A family member 10 (inactive) [Source:HGNC Symbol;Acc:HGNC:19275]	-	-	-	-	GO:0005576//extracellular region	GO:0003676//nucleic acid binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0022409//positive regulation of cell-cell adhesion;GO:0034113//heterotypic cell-cell adhesion;GO:0080154//regulation of fertilization;GO:1902093//positive regulation of flagellated sperm motility	--
ENSG00000182551	32.313	32.722	32.609	40.575	33.891	42.191	1469	1495	1098	1334	1311	1390	ADI1	acireductone dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:30576]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K08967;K08967	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0010309//acireductone dioxygenase [iron(II)-requiring] activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	GO:0006555//methionine metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0019509//L-methionine salvage from methylthioadenosine	--
ENSG00000182552	11.185	12.147	11.078	10.941	9.81	9.748	554	579	369	347	374	344	RWDD4	RWD domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23750]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000182557	1.233	0.814	2.01	1.74	1.492	1.425	44	30	53	46	45	37	SPNS3	sphingolipid transporter 3 (putative) [Source:HGNC Symbol;Acc:HGNC:28433]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0006869//lipid transport;GO:0055085//transmembrane transport	--
ENSG00000182566	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4G	C-type lectin domain family 4 member G [Source:HGNC Symbol;Acc:HGNC:24591]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0030247//polysaccharide binding;GO:0070061//fructose binding;GO:0097367//carbohydrate derivative binding;GO:0120274//virus coreceptor activity;GO:0140081//glycosylated region protein binding	GO:0002710//negative regulation of T cell mediated immunity;GO:0042130//negative regulation of T cell proliferation;GO:0046718//viral entry into host cell;GO:1903902//positive regulation of viral life cycle	--
ENSG00000182568	30.534	35.34	30.073	28.178	23.688	30.506	2589	2350	1780	1415	1755	1711	SATB1	SATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0016605//PML body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II	CUT
ENSG00000182575	1.091	1.356	0.851	0.862	0.709	0.663	127	110	50	46	55	36	NXPH3	neurexophilin 3 [Source:HGNC Symbol;Acc:HGNC:8077]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005102//signaling receptor binding	GO:0007218//neuropeptide signaling pathway	--
ENSG00000182578	60.573	69.064	52.758	36.78	40.831	40.168	4070	4382	2777	1910	2401	2018	CSF1R	colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signaling molecules and interaction;Cancer: overview;Signal transduction;Signal transduction;Immune system;Development and regeneration;Signaling molecules and interaction;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04640//Hematopoietic cell lineage;ko04380//Osteoclast differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05221//Acute myeloid leukemia	K05090;K05090;K05090;K05090;K05090;K05090;K05090;K05090;K05090;K05090;K05090	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex;GO:1990682//CSF1-CSF1R complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005011//macrophage colony-stimulating factor receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0019955//cytokine binding;GO:0042803//protein homodimerization activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002376//immune system process;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008360//regulation of cell shape;GO:0010759//positive regulation of macrophage chemotaxis;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0021772//olfactory bulb development;GO:0021879//forebrain neuron differentiation;GO:0030097//hemopoiesis;GO:0030224//monocyte differentiation;GO:0030225//macrophage differentiation;GO:0030316//osteoclast differentiation;GO:0030335//positive regulation of cell migration;GO:0031401//positive regulation of protein modification process;GO:0031529//ruffle organization;GO:0032722//positive regulation of chemokine production;GO:0033674//positive regulation of kinase activity;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0044794//positive regulation by host of viral process;GO:0045087//innate immune response;GO:0045124//regulation of bone resorption;GO:0045217//cell-cell junction maintenance;GO:0046488//phosphatidylinositol metabolic process;GO:0046777//protein autophosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048584//positive regulation of response to stimulus;GO:0060603//mammary gland duct morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0061518//microglial cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071345//cellular response to cytokine stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0120041//positive regulation of macrophage proliferation;GO:2000147//positive regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization	--
ENSG00000182580	5.181	5.63	3.731	2.183	3.262	1.972	455	497	242	142	242	126	EPHB3	EPH receptor B3 [Source:HGNC Symbol;Acc:HGNC:3394]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05112	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001525//angiogenesis;GO:0001655//urogenital system development;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021952//central nervous system projection neuron axonogenesis;GO:0022038//corpus callosum development;GO:0022407//regulation of cell-cell adhesion;GO:0031290//retinal ganglion cell axon guidance;GO:0033674//positive regulation of kinase activity;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043087//regulation of GTPase activity;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0048538//thymus development;GO:0048546//digestive tract morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051965//positive regulation of synapse assembly;GO:0060021//roof of mouth development;GO:0060996//dendritic spine development;GO:0060997//dendritic spine morphogenesis	--
ENSG00000182583	0	0	0.107	0	0	0.108	0	0	1	0	0	1	VCX	variable charge X-linked [Source:HGNC Symbol;Acc:HGNC:12667]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003682//chromatin binding	GO:0006325//chromatin organization;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0042255//ribosome assembly	--
ENSG00000182585	0.144	0.143	0.088	0.024	0.213	0.074	8	8	1	1	10	3	EPGN	epithelial mitogen [Source:HGNC Symbol;Acc:HGNC:17470]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane	GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitotic nuclear division;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000182591	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP11-1	keratin associated protein 11-1 [Source:HGNC Symbol;Acc:HGNC:18922]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000182600	0.121	0.138	0.094	0.343	0.082	0.071	7	8	4	4	4	3	SNORC	secondary ossification center associated regulator of chondrocyte maturation [Source:HGNC Symbol;Acc:HGNC:33763]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix;GO:0071944//cell periphery	GO:0005515//protein binding	GO:0051216//cartilage development	--
ENSG00000182601	0	0	0	0	0	0	0	0	0	0	0	0	HS3ST4	heparan sulfate-glucosamine 3-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:5200]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity	GO:0030201//heparan sulfate proteoglycan metabolic process	--
ENSG00000182606	21.68	20.302	21.385	20.921	19.288	22.924	1975	2024	1539	1512	1630	1522	TRAK1	trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:1904115//axon cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0017022//myosin binding;GO:0050811//GABA receptor binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006493//protein O-linked glycosylation;GO:0006605//protein targeting;GO:0008333//endosome to lysosome transport;GO:0022008//neurogenesis;GO:0047496//vesicle transport along microtubule;GO:0048311//mitochondrion distribution;GO:0051179//localization;GO:0098957//anterograde axonal transport of mitochondrion	--
ENSG00000182612	580.277	585.676	630.877	781.826	696.876	757.603	22274	22600	17888	22247	22597	21187	TSPAN10	tetraspanin 10 [Source:HGNC Symbol;Acc:HGNC:29942]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000182613	0	0	0	0	0	0	0	0	0	0	0	0	OR2V2	olfactory receptor family 2 subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:15341]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182621	2.426	2.169	1.392	1.187	1.526	2.159	239	201	96	103	129	117	PLCB1	phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Global and overview maps;Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Immune system;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Signal transduction;Cardiovascular disease;Cardiovascular disease;Immune system;Immune system;Infectious disease: parasitic;Signal transduction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Nervous system;Circulatory system;Neurodegenerative disease;Signal transduction;Endocrine system;Circulatory system;Nervous system;Endocrine system;Immune system;Endocrine system;Signal transduction;Endocrine system;Nervous system;Nervous system;Nervous system;Infectious disease: parasitic;Endocrine system;Endocrine system;Infectious disease: parasitic;Digestive system;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Cellular community - eukaryotes;Endocrine system;Sensory system;Digestive system;Endocrine system;Carbohydrate metabolism;Endocrine system;Nervous system;Endocrine system;Endocrine system;Nervous system;Excretory system;Digestive system	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05146//Amoebiasis;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko05142//Chagas disease;ko04922//Glucagon signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05143//African trypanosomiasis;ko04972//Pancreatic secretion;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04911//Insulin secretion;ko04742//Taste transduction;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko00562//Inositol phosphate metabolism;ko04924//Renin secretion;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion;ko04730//Long-term depression;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption"	K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858;K05858	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0110165//cellular anatomical entity	"GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005521//lamin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding"	"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0007420//brain development;GO:0007612//learning;GO:0007613//memory;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0010243//response to organonitrogen compound;GO:0016042//lipid catabolic process;GO:0021987//cerebral cortex development;GO:0031161//phosphatidylinositol catabolic process;GO:0032735//positive regulation of interleukin-12 production;GO:0032957//inositol trisphosphate metabolic process;GO:0034284//response to monosaccharide;GO:0035556//intracellular signal transduction;GO:0035722//interleukin-12-mediated signaling pathway;GO:0035723//interleukin-15-mediated signaling pathway;GO:0040019//positive regulation of embryonic development;GO:0043434//response to peptide hormone;GO:0045444//fat cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0046488//phosphatidylinositol metabolic process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048639//positive regulation of developmental growth;GO:0050790//regulation of catalytic activity;GO:0051726//regulation of cell cycle;GO:0060466//activation of meiosis involved in egg activation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0080154//regulation of fertilization;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:0099178//regulation of retrograde trans-synaptic signaling by endocanabinoid;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902618//cellular response to fluoride;GO:1903140//regulation of establishment of endothelial barrier;GO:1904117//cellular response to vasopressin;GO:1904637//cellular response to ionomycin;GO:1905631//cellular response to glyceraldehyde;GO:2000344//positive regulation of acrosome reaction;GO:2000438//negative regulation of monocyte extravasation;GO:2000560//positive regulation of CD24 production"	--
ENSG00000182628	24.18	21.293	23.279	20.554	19.89	22.278	696	661	497	410	478	488	SKA2	spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000940//outer kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule"	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division	--
ENSG00000182631	0	0	0	0.026	0	0	0	0	0	1	0	0	RXFP3	relaxin family peptide receptor 3 [Source:HGNC Symbol;Acc:HGNC:24883]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K08397;K08397	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0032467//positive regulation of cytokinesis	--
ENSG00000182634	0	0	0	0	0	0	0	0	0	0	0	0	OR10G7	olfactory receptor family 10 subfamily G member 7 [Source:HGNC Symbol;Acc:HGNC:14842]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182636	44.164	43.586	46.235	49.856	47.514	49.574	1746	1732	1350	1460	1587	1426	NDN	"necdin, MAGE family member [Source:HGNC Symbol;Acc:HGNC:7675]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043204//perikaryon	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043015//gamma-tubulin binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0003016//respiratory system process;GO:0006355//regulation of transcription, DNA-templated;GO:0007409//axonogenesis;GO:0007413//axonal fasciculation;GO:0007417//central nervous system development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008285//negative regulation of cell population proliferation;GO:0008347//glial cell migration;GO:0009791//post-embryonic development;GO:0019233//sensory perception of pain;GO:0030182//neuron differentiation;GO:0040008//regulation of growth;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048666//neuron development;GO:0048675//axon extension;GO:0048871//multicellular organismal homeostasis;GO:0071514//genetic imprinting;GO:0090312//positive regulation of protein deacetylation"	--
ENSG00000182645	0	0	0	0	0	0	0	0	0	0	0	0	CCDC172	coiled-coil domain containing 172 [Source:HGNC Symbol;Acc:HGNC:30524]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection;GO:0097225//sperm midpiece	GO:0005515//protein binding	-	--
ENSG00000182652	0	0	0	0	0	0	0	0	0	0	0	0	OR4Q3	olfactory receptor family 4 subfamily Q member 3 [Source:HGNC Symbol;Acc:HGNC:15426]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182667	5.21	5.644	1.723	3.417	3.154	0.636	216	259	44	105	110.04	27	NTM	neurotrimin [Source:HGNC Symbol;Acc:HGNC:17941]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0008038//neuron recognition	--
ENSG00000182670	57.093	42.116	35.176	25.714	34.192	31.316	8142	5968.03	3761	2786	3930	3280	TTC3	tetratricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12393]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000182674	0.167	0.192	0.279	0.243	0.122	0.265	13	15	16	14	8	15	KCNB2	potassium voltage-gated channel subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:6232]	-	-	-	-	GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006940//regulation of smooth muscle contraction;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0072659//protein localization to plasma membrane	--
ENSG00000182676	0	0	0	0	0	0	0	0	0	0	0	0	PPP1R27	protein phosphatase 1 regulatory subunit 27 [Source:HGNC Symbol;Acc:HGNC:16813]	-	-	-	-	-	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0019902//phosphatase binding	GO:0043086//negative regulation of catalytic activity	--
ENSG00000182685	0.467	0.91	1.259	0.315	1.546	1.369	8	12	14	4	18	14	BRICD5	BRICHOS domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28309]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0042127//regulation of cell population proliferation	--
ENSG00000182687	0.035	0	0.048	0.19	0	0	1	0	1	4	0	0	GALR2	galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4133]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04231	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004966//galanin receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0042923//neuropeptide binding	GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007275//multicellular organism development;GO:0007611//learning or memory;GO:0007631//feeding behavior;GO:0031175//neuron projection development;GO:0043647//inositol phosphate metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046488//phosphatidylinositol metabolic process;GO:0090663//galanin-activated signaling pathway;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity	--
ENSG00000182698	0	0	0	0	0	0	0	0	0	0	0	0	RESP18	regulated endocrine specific protein 18 [Source:HGNC Symbol;Acc:HGNC:33762]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle	-	-	--
ENSG00000182700	3.209	1.832	2.21	1.431	1.651	1.841	230	132	117	76	100	96	IGIP	IgA inducing protein [Source:HGNC Symbol;Acc:HGNC:33847]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000182704	79.745	80.394	83.724	100.809	106.845	96.43	4296	4328	3284	4004	4795	3779	TSKU	"tsukushi, small leucine rich proteoglycan [Source:HGNC Symbol;Acc:HGNC:28850]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0050431//transforming growth factor beta binding	GO:0003431//growth plate cartilage chondrocyte development;GO:0007399//nervous system development;GO:0008203//cholesterol metabolic process;GO:0010468//regulation of gene expression;GO:0010977//negative regulation of neuron projection development;GO:0021540//corpus callosum morphogenesis;GO:0021670//lateral ventricle development;GO:0021766//hippocampus development;GO:0021960//anterior commissure morphogenesis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0033344//cholesterol efflux;GO:0042060//wound healing;GO:0042632//cholesterol homeostasis;GO:0042635//positive regulation of hair cycle;GO:0043010//camera-type eye development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0061073//ciliary body morphogenesis;GO:0097009//energy homeostasis;GO:0098868//bone growth;GO:1904761//negative regulation of myofibroblast differentiation	--
ENSG00000182712	7.987	9.237	6.657	8.379	6.442	8.304	145.96	169.66	89.84	113.35	99.41	110.41	CMC4	C-X9-C motif containing 4 [Source:HGNC Symbol;Acc:HGNC:35428]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space	-	-	--
ENSG00000182718	534.367	569.176	492.616	489.267	425.308	419.728	15985	17103	11173	10753	10947	9139	ANXA2	annexin A2 [Source:HGNC Symbol;Acc:HGNC:537]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K17092	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016363//nuclear matrix;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0035578//azurophil granule lumen;GO:0042470//melanosome;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0090575//RNA polymerase II transcription regulator complex;GO:0098797//plasma membrane protein complex;GO:1990665//AnxA2-p11 complex;GO:1990667//PCSK9-AnxA2 complex	"GO:0001786//phosphatidylserine binding;GO:0002020//protease binding;GO:0003723//RNA binding;GO:0004859//phospholipase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008092//cytoskeletal protein binding;GO:0019834//phospholipase A2 inhibitor activity;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0046790//virion binding;GO:0048306//calcium-dependent protein binding;GO:0098641//cadherin binding involved in cell-cell adhesion"	GO:0001525//angiogenesis;GO:0001765//membrane raft assembly;GO:0001921//positive regulation of receptor recycling;GO:0002091//negative regulation of receptor internalization;GO:0006900//vesicle budding from membrane;GO:0010756//positive regulation of plasminogen activation;GO:0010951//negative regulation of endopeptidase activity;GO:0031340//positive regulation of vesicle fusion;GO:0032804//negative regulation of low-density lipoprotein particle receptor catabolic process;GO:0036035//osteoclast development;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043086//negative regulation of catalytic activity;GO:0044090//positive regulation of vacuole organization;GO:0045921//positive regulation of exocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0070588//calcium ion transmembrane transport;GO:0098609//cell-cell adhesion;GO:1905581//positive regulation of low-density lipoprotein particle clearance;GO:1905597//positive regulation of low-density lipoprotein particle receptor binding;GO:1905599//positive regulation of low-density lipoprotein receptor activity;GO:1905602//positive regulation of receptor-mediated endocytosis involved in cholesterol transport;GO:1905686//positive regulation of plasma membrane repair	--
ENSG00000182732	0.277	0.271	0.347	0.521	0.338	0.156	15	10	11	29	22	11	RGS6	regulator of G protein signaling 6 [Source:HGNC Symbol;Acc:HGNC:10002]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000182742	0	0	0	0	0	0	0	0	0	0	0	0	HOXB4	homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002011//morphogenesis of an epithelial sheet;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008283//cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0030097//hemopoiesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048103//somatic stem cell division;GO:0048536//spleen development;GO:0048539//bone marrow development;GO:0048704//embryonic skeletal system morphogenesis;GO:0048705//skeletal system morphogenesis;GO:0060216//definitive hemopoiesis;GO:0060218//hematopoietic stem cell differentiation;GO:2000738//positive regulation of stem cell differentiation"	Homeobox
ENSG00000182747	1.44	1.494	2.117	3.417	3.069	2.63	70	73	76	123	126	93	SLC35D3	solute carrier family 35 member D3 [Source:HGNC Symbol;Acc:HGNC:15621]	-	-	-	-	GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005461//UDP-glucuronic acid transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463//UDP-N-acetylgalactosamine transmembrane transporter activity;GO:0015297//antiporter activity	GO:0008643//carbohydrate transport;GO:0015787//UDP-glucuronic acid transmembrane transport;GO:0015789//UDP-N-acetylgalactosamine transmembrane transport;GO:0055085//transmembrane transport;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0097009//energy homeostasis;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000182749	3.537	4.037	4.522	4.397	4.919	3.637	198	226	186	182	232	149	PAQR7	progestin and adipoQ receptor family member 7 [Source:HGNC Symbol;Acc:HGNC:23146]	Human Diseases	Cancer: overview	ko05207//Chemical carcinogenesis - receptor activation	K25039	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038023//signaling receptor activity	GO:0030154//cell differentiation;GO:0043401//steroid hormone mediated signaling pathway;GO:0048477//oogenesis;GO:0048545//response to steroid hormone	--
ENSG00000182752	1.103	0.87	0.708	0.67	0.921	0.701	251	199	119	113	177	116	PAPPA	pappalysin 1 [Source:HGNC Symbol;Acc:HGNC:8602]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007565//female pregnancy;GO:0032354//response to follicle-stimulating hormone;GO:0044267//cellular protein metabolic process;GO:0051384//response to glucocorticoid	--
ENSG00000182759	0.199	0.234	0.245	0.512	0.492	0.447	11	13	10	21	23	18	MAFA	MAF bZIP transcription factor A [Source:HGNC Symbol;Acc:HGNC:23145]	Human Diseases;Human Diseases	Endocrine and metabolic disease;Endocrine and metabolic disease	ko04930//Type II diabetes mellitus;ko04950//Maturity onset diabetes of the young	K07595;K07595	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007263//nitric oxide mediated signal transduction;GO:0009749//response to glucose;GO:0030073//insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000182768	75.089	79.511	75.007	75.404	70.415	80.339	2057.89	2149.71	1500.45	1533.88	1609.35	1615.13	NGRN	"neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077]"	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031966//mitochondrial membrane;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0061668//mitochondrial ribosome assembly;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000182771	0	0.008	0.02	0	0.018	0.041	0	1	1	0	1	2	GRID1	glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05206	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:0110165//cellular anatomical entity	GO:0004970//ionotropic glutamate receptor activity;GO:0005216//ion channel activity;GO:0008066//glutamate receptor activity;GO:0015276//ligand-gated ion channel activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0035176//social behavior;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0050804//modulation of chemical synaptic transmission;GO:0060078//regulation of postsynaptic membrane potential"	--
ENSG00000182774	333.934	369.285	330.521	366.305	290.311	299.25	3387.59	3763	2473.9	2749.9	2489.67	2208	RPS17	ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:10397]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02962;K02962	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0006413//translational initiation;GO:0034101//erythrocyte homeostasis;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000182782	0	0	0	0	0.055	0	0	0	0	0	2	0	HCAR2	hydroxycarboxylic acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:24827]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K08402	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0004930//G protein-coupled receptor activity;GO:0070553//nicotinic acid receptor activity	GO:0001781//neutrophil apoptotic process;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0050995//negative regulation of lipid catabolic process;GO:0070165//positive regulation of adiponectin secretion	--
ENSG00000182783	0	0	0	0	0	0	0	0	0	0	0	0	OR2T29	olfactory receptor family 2 subfamily T member 29 [Source:HGNC Symbol;Acc:HGNC:31253]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182791	0.234	0.465	0.181	0.293	0.336	0.344	14	28	8	13	17	15	CCDC87	coiled-coil domain containing 87 [Source:HGNC Symbol;Acc:HGNC:25579]	-	-	-	-	-	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0030154//cell differentiation;GO:1905516//positive regulation of fertilization;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000182793	0	0	0	0	0	0	0	0	0	0	0	0	GSTA5	glutathione S-transferase alpha 5 [Source:HGNC Symbol;Acc:HGNC:19662]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process	--
ENSG00000182795	0.427	0.423	0.329	0.527	0.43	0.93	38	32	27	30	31	59	C1orf116	chromosome 1 open reading frame 116 [Source:HGNC Symbol;Acc:HGNC:28667]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000182798	0.245	0.301	0.182	0.136	0.159	0.185	7	9	4	3	4	4	MAGEB17	MAGE family member B17 [Source:HGNC Symbol;Acc:HGNC:17418]	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000182809	31.063	29.153	22.221	17.183	19.474	19.518	759	716	401	311	402	347	CRIP2	cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361]	-	-	-	-	GO:0005938//cell cortex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0008284//positive regulation of cell population proliferation;GO:0030097//hemopoiesis	--
ENSG00000182810	3.808	3.768	3.916	5.309	4.753	4.804	183	182	139	189	193	168	DDX28	DEAD-box helicase 28 [Source:HGNC Symbol;Acc:HGNC:17330]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0035770//ribonucleoprotein granule;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0019843//rRNA binding	GO:0042254//ribosome biogenesis;GO:1902775//mitochondrial large ribosomal subunit assembly	--
ENSG00000182816	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP13-2	keratin associated protein 13-2 [Source:HGNC Symbol;Acc:HGNC:18923]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000182827	15.214	16.903	14.717	12.022	12.674	12.22	1131	1263	808	662	796	661	ACBD3	acyl-CoA binding domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15453]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23935	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0016020//membrane	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process	--
ENSG00000182831	10.453	9.153	10.152	9.442	9.3	9.131	1538	1379	1111	1014	1177	990	C16orf72	chromosome 16 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:30103]	-	-	-	-	-	GO:0005515//protein binding	GO:1901797//negative regulation of signal transduction by p53 class mediator	--
ENSG00000182836	1.722	1.024	1.169	0.804	0.969	1.249	270	161	135	95	128	143	PLCXD3	phosphatidylinositol specific phospholipase C X domain containing 3 [Source:HGNC Symbol;Acc:HGNC:31822]	-	-	-	-	GO:0005737//cytoplasm;GO:0045202//synapse	GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process	--
ENSG00000182853	0	0	0	0	0	0	0	0	0	0	0	0	VMO1	vitelline membrane outer layer 1 homolog [Source:HGNC Symbol;Acc:HGNC:30387]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000182854	0	0	0	0	0	0	0	0	0	0	0	0	OR4F15	olfactory receptor family 4 subfamily F member 15 [Source:HGNC Symbol;Acc:HGNC:15078]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182858	16.655	18.356	18.442	14.848	20.644	18.379	1281	1226	1030	907	1164	965	ALG12	"ALG12 alpha-1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:19358]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03847;K03847;K03847	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0052917//dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase"	GO:0006457//protein folding;GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0097502//mannosylation	--
ENSG00000182866	0	0	0	0	0.027	0	0	0	0	0	1	0	LCK	"LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524]"	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: bacterial;Immune system;Signal transduction;Development and regeneration;Immune disease;Immune system;Immune system;Immune system;Cancer: overview	ko05166//Human T-cell leukemia virus 1 infection;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko04380//Osteoclast differentiation;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K05856;K05856;K05856;K05856;K05856;K05856;K05856;K05856;K05856;K05856	GO:0000242//pericentriolar material;GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0042169//SH2 domain binding;GO:0042608//T cell receptor binding;GO:0042609//CD4 receptor binding;GO:0042610//CD8 receptor binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0051117//ATPase binding	GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0006882//cellular zinc ion homeostasis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009410//response to xenobiotic stimulus;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0030217//T cell differentiation;GO:0031295//T cell costimulation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0035556//intracellular signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0038094//Fc-gamma receptor signaling pathway;GO:0045087//innate immune response;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0050900//leukocyte migration;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051249//regulation of lymphocyte activation;GO:1903039//positive regulation of leukocyte cell-cell adhesion;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000182870	1.89	1.668	1.868	2.241	1.887	2.597	115	102	80	101	97	112	GALNT9	polypeptide N-acetylgalactosaminyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:4131]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation;GO:0016266//O-glycan processing;GO:0034645//cellular macromolecule biosynthetic process	--
ENSG00000182871	257.23	279.406	256.895	233.654	262.151	229.796	28654.73	31345.86	21129.44	19309.91	24706.46	18578.36	COL18A1	collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K06823	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001886//endothelial cell morphogenesis;GO:0007155//cell adhesion;GO:0007601//visual perception;GO:0008285//negative regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0030198//extracellular matrix organization	--
ENSG00000182872	20.456	22.873	21.045	21.072	23.265	20.343	1397.67	1567.2	1062.65	1073.88	1335.15	1010	RBM10	RNA binding motif protein 10 [Source:HGNC Symbol;Acc:HGNC:9896]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0035198//miRNA binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008150//biological_process;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0034391//regulation of smooth muscle cell apoptotic process;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0042981//regulation of apoptotic process;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0070935//3'-UTR-mediated mRNA stabilization"	--
ENSG00000182885	0.021	0	0	0	0	0	1	0	0	0	0	0	ADGRG3	adhesion G protein-coupled receptor G3 [Source:HGNC Symbol;Acc:HGNC:13728]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030183//B cell differentiation;GO:0030334//regulation of cell migration;GO:0032792//negative regulation of CREB transcription factor activity;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000182890	4.3	4.505	4.459	6.128	5.863	6.562	221.64	233.38	169.73	233.95	255.33	246.1	GLUD2	glutamate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4336]	Metabolism;Cellular Processes;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Cell growth and death;Global and overview maps;Amino acid metabolism;Excretory system;Amino acid metabolism;Energy metabolism	"ko01100//Metabolic pathways;ko04217//Necroptosis;ko01200//Carbon metabolism;ko00250//Alanine, aspartate and glutamate metabolism;ko04964//Proximal tubule bicarbonate reclamation;ko00220//Arginine biosynthesis;ko00910//Nitrogen metabolism"	K00261;K00261;K00261;K00261;K00261;K00261;K00261	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0004352//glutamate dehydrogenase (NAD+) activity;GO:0004353//glutamate dehydrogenase [NAD(P)+] activity;GO:0004354//glutamate dehydrogenase (NADP+) activity;GO:0005525//GTP binding;GO:0016491//oxidoreductase activity;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;GO:0043531//ADP binding;GO:0070728//leucine binding"	GO:0006520//cellular amino acid metabolic process;GO:0006536//glutamate metabolic process;GO:0006537//glutamate biosynthetic process;GO:0006538//glutamate catabolic process	--
ENSG00000182896	0	0	0	0	0	0	0	0	0	0	0	0	TMEM95	transmembrane protein 95 [Source:HGNC Symbol;Acc:HGNC:27898]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0097524//sperm plasma membrane	GO:0005515//protein binding	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization	--
ENSG00000182898	0	0	0	0	0	0	0	0	0	0	0	0	TCHHL1	trichohyalin like 1 [Source:HGNC Symbol;Acc:HGNC:31796]	-	-	-	-	-	GO:0046914//transition metal ion binding	-	--
ENSG00000182899	231.479	261.665	246.139	253.081	206.86	203.22	3142	3418	2450	2581	2250	2047	RPL35A	ribosomal protein L35a [Source:HGNC Symbol;Acc:HGNC:10345]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02917;K02917	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000182901	0.673	0.363	0.351	0.2	0.341	0.231	34	17	12	7	15	8	RGS7	regulator of G protein signaling 7 [Source:HGNC Symbol;Acc:HGNC:10003]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft	GO:0001965//G-protein alpha-subunit binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0031681//G-protein beta-subunit binding	GO:0001975//response to amphetamine;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007420//brain development;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009409//response to cold;GO:0009968//negative regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0045471//response to ethanol;GO:1901381//positive regulation of potassium ion transmembrane transport	--
ENSG00000182902	0.245	0.401	0.374	0.298	0.522	0.394	11	18	12	10	20	13	SLC25A18	solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005280//amino acid:proton symporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0005515//protein binding;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0015810//aspartate transmembrane transport;GO:0015813//L-glutamate transmembrane transport;GO:0043490//malate-aspartate shuttle;GO:0055085//transmembrane transport;GO:0070778//L-aspartate transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000182903	8.451	6.542	6.496	4.206	5.668	6.834	411	283	206	167	223	241	ZNF721	zinc finger protein 721 [Source:HGNC Symbol;Acc:HGNC:29425]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000182916	4.108	5.758	4.709	4.219	3.086	4.108	88	123	72	63	54	62	TCEAL7	transcription elongation factor A like 7 [Source:HGNC Symbol;Acc:HGNC:28336]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0050699//WW domain binding	"GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000182919	34.433	26.986	30.935	33.606	31.048	33.735	1442.85	1186.12	954.88	926.97	991	1063.75	C11orf54	chromosome 11 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:30204]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0070062//extracellular exosome	"GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	-	--
ENSG00000182923	7.495	7.374	6.739	5.852	6.635	5.737	468.03	420.57	280.07	256	292.04	238	CEP63	centrosomal protein 63 [Source:HGNC Symbol;Acc:HGNC:25815]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007099//centriole replication;GO:0042770//signal transduction in response to DNA damage;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0098535//de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	--
ENSG00000182931	0	0	0	0	0	0	0	0	0	0	0	0	WFDC10B	WAP four-disulfide core domain 10B [Source:HGNC Symbol;Acc:HGNC:20479]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010951//negative regulation of endopeptidase activity;GO:0019731//antibacterial humoral response;GO:0043086//negative regulation of catalytic activity;GO:0045087//innate immune response;GO:0052547//regulation of peptidase activity	--
ENSG00000182934	59.737	61.74	59.844	61.026	61.762	59.026	3693	3839	2736	2794	3225	2660	SRPRA	SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K13431	GO:0005783//endoplasmic reticulum;GO:0005785//signal recognition particle receptor complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003924//GTPase activity;GO:0005047//signal recognition particle binding;GO:0005525//GTP binding	"GO:0006605//protein targeting;GO:0006613//cotranslational protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006617//SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition;GO:0006886//intracellular protein transport;GO:0045047//protein targeting to ER"	--
ENSG00000182938	0	0	0	0	0	0	0	0	0	0	0	0	OTOP3	otopetrin 3 [Source:HGNC Symbol;Acc:HGNC:19658]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015252//proton channel activity	GO:0006811//ion transport;GO:1902600//proton transmembrane transport	--
ENSG00000182944	68.248	69.485	74.615	76.679	72.847	72.198	2866	2958	2376	2403	2539	2259	EWSR1	EWS RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3508]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K13209	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0015030//Cajal body;GO:0016020//membrane	GO:0003676//nucleic acid binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000182950	0.128	0.169	0	0.057	0	0	3	4	0	1	0	0	ODF3L1	outer dense fiber of sperm tails 3 like 1 [Source:HGNC Symbol;Acc:HGNC:28735]	-	-	-	-	GO:0005856//cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000182952	23.944	19.23	21.065	18.491	18.767	18.415	965	779	627	552	639	540	HMGN4	high mobility group nucleosomal binding domain 4 [Source:HGNC Symbol;Acc:HGNC:4989]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding	GO:0006325//chromatin organization	--
ENSG00000182957	12.92	10.632	11.474	8.753	9.493	9.773	2135	1752.03	1322.62	996	1220	1157	SPATA13	spermatogenesis associated 13 [Source:HGNC Symbol;Acc:HGNC:23222]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05769	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0016477//cell migration;GO:0030032//lamellipodium assembly;GO:0030334//regulation of cell migration;GO:0046847//filopodium assembly;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000182963	5.068	3.57	6.907	2.454	3.297	2.671	503	452	280	161	215	202	GJC1	gap junction protein gamma 1 [Source:HGNC Symbol;Acc:HGNC:4280]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0086020//gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	GO:0001570//vasculogenesis;GO:0006936//muscle contraction;GO:0007043//cell-cell junction assembly;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007268//chemical synaptic transmission;GO:0007507//heart development;GO:0007601//visual perception;GO:0016264//gap junction assembly;GO:0034220//ion transmembrane transport;GO:0048468//cell development;GO:0048738//cardiac muscle tissue development;GO:0055085//transmembrane transport;GO:0086014//atrial cardiac muscle cell action potential;GO:0086021//SA node cell to atrial cardiac muscle cell communication by electrical coupling;GO:0086053//AV node cell to bundle of His cell communication by electrical coupling	--
ENSG00000182968	0	0	0	0	0	0	0	0	0	0	0	0	SOX1	SRY-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11189]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001764//neuron migration;GO:0002089//lens morphogenesis in camera-type eye;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0021521//ventral spinal cord interneuron specification;GO:0021879//forebrain neuron differentiation;GO:0021884//forebrain neuron development;GO:0030154//cell differentiation;GO:0030900//forebrain development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048713//regulation of oligodendrocyte differentiation;GO:1904936//interneuron migration;GO:1990830//cellular response to leukemia inhibitory factor"	HMG
ENSG00000182973	7.805	7.271	6.535	5.716	6.672	5.616	441	414	277	232	321	234	CNOT10	CCR4-NOT transcription complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:23817]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12607	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0030014//CCR4-NOT complex	GO:0005515//protein binding	GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0031047//gene silencing by RNA	--
ENSG00000182974	0	0	0	0	0	0	0	0	0	0	0	0	OR4M2B	olfactory receptor family 4 subfamily M member 2B [Source:HGNC Symbol;Acc:HGNC:55109]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000182979	17.693	17.838	17.953	18.145	20.75	20.694	1022	1029	749	776	1002	862	MTA1	metastasis associated 1 [Source:HGNC Symbol;Acc:HGNC:7410]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016581//NuRD complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006302//double-strand break repair;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0010212//response to ionizing radiation;GO:0016575//histone deacetylation;GO:0032922//circadian regulation of gene expression;GO:0040029//regulation of gene expression, epigenetic;GO:0042659//regulation of cell fate specification;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045475//locomotor rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:1902499//positive regulation of protein autoubiquitination;GO:2000736//regulation of stem cell differentiation"	zf-GATA
ENSG00000182983	0.17	0.301	0.125	0.133	0.109	0.113	14	20	7	11	7	6	ZNF662	zinc finger protein 662 [Source:HGNC Symbol;Acc:HGNC:31930]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000182985	25.111	24.656	21.557	21.99	23.189	20.71	1607	1408	944	940	1125	1055	CADM1	cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06781	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0001819//positive regulation of cytokine production;GO:0001889//liver development;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008037//cell recognition;GO:0030154//cell differentiation;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0051606//detection of stimulus	--
ENSG00000182986	4.942	3.515	4.867	3.746	4.275	3.633	393	371	307	264	301	247	ZNF320	zinc finger protein 320 [Source:HGNC Symbol;Acc:HGNC:13842]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000182993	0.76	0.907	0.453	0.616	1.151	0.794	25	30	11	15	32	19	C12orf60	chromosome 12 open reading frame 60 [Source:HGNC Symbol;Acc:HGNC:28726]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183010	21.15	20.887	20.71	19.753	16.252	13.461	530	558	416	355	427	348	PYCR1	pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism	K00286;K00286;K00286	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004735//pyrroline-5-carboxylate reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding	GO:0006561//proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0034599//cellular response to oxidative stress;GO:0051881//regulation of mitochondrial membrane potential;GO:0055129//L-proline biosynthetic process;GO:1903206//negative regulation of hydrogen peroxide-induced cell death	--
ENSG00000183011	27.177	27.482	36.082	38.771	29.993	33.386	310	308	297	317	283	271	NAA38	"N-alpha-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005844//polysome;GO:0031417//NatC complex	GO:0005515//protein binding	GO:0043066//negative regulation of apoptotic process	--
ENSG00000183018	129.825	131.559	141.827	150.423	143.11	167.679	8973	9208.91	7206	7661	8364	8359	SPNS2	sphingolipid transporter 2 [Source:HGNC Symbol;Acc:HGNC:26992]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity;GO:0046624//sphingolipid transporter activity	GO:0001782//B cell homeostasis;GO:0002260//lymphocyte homeostasis;GO:0002920//regulation of humoral immune response;GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006665//sphingolipid metabolic process;GO:0006869//lipid transport;GO:0030148//sphingolipid biosynthetic process;GO:0043029//T cell homeostasis;GO:0048073//regulation of eye pigmentation;GO:0048535//lymph node development;GO:0055085//transmembrane transport;GO:0060348//bone development;GO:0072676//lymphocyte migration	--
ENSG00000183019	0	0	0	0	0	0	0	0	0	0	0	0	MCEMP1	mast cell expressed membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:27291]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000183020	22.204	24.075	20.642	22.586	24.247	26.997	1640	1640	1262	1194	1288	1203	AP2A2	adaptor related protein complex 2 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:562]	Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K11824;K11824;K11824;K11824	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030122//AP-2 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0036020//endolysosome membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0097708//intracellular vesicle;GO:0101003//ficolin-1-rich granule membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0035615//clathrin adaptor activity;GO:0097718//disordered domain specific binding;GO:0140312//cargo adaptor activity	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0072583//clathrin-dependent endocytosis;GO:0098884//postsynaptic neurotransmitter receptor internalization	--
ENSG00000183023	1.874	1.877	1.472	0.726	0.768	0.691	207	251	101	54	82	47	SLC8A1	solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068]	Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Sensory system;Signal transduction;Signal transduction;Cardiovascular disease;Circulatory system;Signal transduction;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease;Digestive system;Excretory system	ko04740//Olfactory transduction;ko04020//Calcium signaling pathway;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04974//Protein digestion and absorption;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption	K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849;K05849	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030315//T-tubule;GO:0030424//axon;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043679//axon terminus;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0071944//cell periphery;GO:0098794//postsynapse;GO:0099055//integral component of postsynaptic membrane	GO:0005432//calcium:sodium antiporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008092//cytoskeletal protein binding;GO:0015297//antiporter activity;GO:0015491//cation:cation antiporter activity;GO:0030506//ankyrin binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0099580//ion antiporter activity involved in regulation of postsynaptic membrane potential;GO:1905060//calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GO:0001666//response to hypoxia;GO:0002026//regulation of the force of heart contraction;GO:0002027//regulation of heart rate;GO:0002028//regulation of sodium ion transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006883//cellular sodium ion homeostasis;GO:0006936//muscle contraction;GO:0007154//cell communication;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0009749//response to glucose;GO:0010468//regulation of gene expression;GO:0010649//regulation of cell communication by electrical coupling;GO:0010763//positive regulation of fibroblast migration;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014829//vascular associated smooth muscle contraction;GO:0021537//telencephalon development;GO:0030001//metal ion transport;GO:0030501//positive regulation of bone mineralization;GO:0033198//response to ATP;GO:0034614//cellular response to reactive oxygen species;GO:0035725//sodium ion transmembrane transport;GO:0035902//response to immobilization stress;GO:0035994//response to muscle stretch;GO:0036376//sodium ion export across plasma membrane;GO:0042542//response to hydrogen peroxide;GO:0044557//relaxation of smooth muscle;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0051924//regulation of calcium ion transport;GO:0055013//cardiac muscle cell development;GO:0055074//calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0055119//relaxation of cardiac muscle;GO:0060048//cardiac muscle contraction;GO:0060401//cytosolic calcium ion transport;GO:0060402//calcium ion transport into cytosol;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0071313//cellular response to caffeine;GO:0071320//cellular response to cAMP;GO:0071456//cellular response to hypoxia;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0098703//calcium ion import across plasma membrane;GO:0098719//sodium ion import across plasma membrane;GO:0098735//positive regulation of the force of heart contraction;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1901660//calcium ion export;GO:1903779//regulation of cardiac conduction	--
ENSG00000183024	0	0	0	0	0	0	0	0	0	0	0	0	OR1G1	olfactory receptor family 1 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:8204]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183032	0.111	0.209	0.098	0.23	0.392	0.384	9	17	5.85	7	11	10	SLC25A21	solute carrier family 25 member 21 [Source:HGNC Symbol;Acc:HGNC:14411]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015139//alpha-ketoglutarate transmembrane transporter activity	GO:0006554//lysine catabolic process;GO:0055085//transmembrane transport;GO:1990550//mitochondrial alpha-ketoglutarate transmembrane transport	--
ENSG00000183034	0	0	0	0	0	0.031	0	0	0	0	0	1	OTOP2	otopetrin 2 [Source:HGNC Symbol;Acc:HGNC:19657]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015252//proton channel activity	GO:0006811//ion transport;GO:1902600//proton transmembrane transport	--
ENSG00000183035	0	0	0	0	0	0	0	0	0	0	0	0	CYLC1	cylicin 1 [Source:HGNC Symbol;Acc:HGNC:2582]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0033150//cytoskeletal calyx;GO:0043159//acrosomal matrix	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton	GO:0007010//cytoskeleton organization;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000183036	62.805	60.445	84.558	85.18	66.481	84.806	698	674	693	700	623	684	PCP4	Purkinje cell protein 4 [Source:HGNC Symbol;Acc:HGNC:8742]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0045666//positive regulation of neuron differentiation;GO:0099004//calmodulin dependent kinase signaling pathway	--
ENSG00000183044	2.221	2.449	2.469	1.798	2.59	2.496	216	244	175	132	198	173	ABAT	4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23]	Metabolism;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nervous system;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko04727//GABAergic synapse;ko00280//Valine, leucine and isoleucine degradation;ko00250//Alanine, aspartate and glutamate metabolism;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism;ko00650//Butanoate metabolism"	K13524;K13524;K13524;K13524;K13524;K13524;K13524	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0032144//4-aminobutyrate transaminase complex;GO:0043005//neuron projection	GO:0003824//catalytic activity;GO:0003867//4-aminobutyrate transaminase activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0032145//succinate-semialdehyde dehydrogenase binding;GO:0034386//4-aminobutyrate:2-oxoglutarate transaminase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047298//(S)-3-amino-2-methylpropionate transaminase activity;GO:0051536//iron-sulfur cluster binding	GO:0001666//response to hypoxia;GO:0007568//aging;GO:0007620//copulation;GO:0007626//locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0009450//gamma-aminobutyric acid catabolic process;GO:0010039//response to iron ion;GO:0014053//negative regulation of gamma-aminobutyric acid secretion;GO:0021549//cerebellum development;GO:0031652//positive regulation of heat generation;GO:0032024//positive regulation of insulin secretion;GO:0033602//negative regulation of dopamine secretion;GO:0035094//response to nicotine;GO:0035640//exploration behavior;GO:0042135//neurotransmitter catabolic process;GO:0042220//response to cocaine;GO:0045471//response to ethanol;GO:0045776//negative regulation of blood pressure;GO:0045964//positive regulation of dopamine metabolic process;GO:0048148//behavioral response to cocaine;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0090331//negative regulation of platelet aggregation;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:1902722//positive regulation of prolactin secretion;GO:1904450//positive regulation of aspartate secretion	--
ENSG00000183048	16.701	18.948	17.424	20.973	20.45	18.233	631	704	486	589	651	497	SLC25A10	solute carrier family 25 member 10 [Source:HGNC Symbol;Acc:HGNC:10980]	Organismal Systems	Excretory system	ko04964//Proximal tubule bicarbonate reclamation	K13577	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0005515//protein binding;GO:0015116//sulfate transmembrane transporter activity;GO:0015117//thiosulfate transmembrane transporter activity;GO:0015131//oxaloacetate transmembrane transporter activity;GO:0015140//malate transmembrane transporter activity;GO:0015141//succinate transmembrane transporter activity;GO:0015297//antiporter activity	"GO:0006094//gluconeogenesis;GO:0006811//ion transport;GO:0006835//dicarboxylic acid transport;GO:0006839//mitochondrial transport;GO:0008272//sulfate transport;GO:0015709//thiosulfate transport;GO:0015729//oxaloacetate transport;GO:0035435//phosphate ion transmembrane transport;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0071422//succinate transmembrane transport;GO:0071423//malate transmembrane transport;GO:1902356//oxaloacetate(2-) transmembrane transport;GO:1902358//sulfate transmembrane transport"	--
ENSG00000183049	0.638	0.557	0.295	0.338	0.756	0.593	87	94	30	42	75	49	CAMK1D	calcium/calmodulin dependent protein kinase ID [Source:HGNC Symbol;Acc:HGNC:19341]	Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Endocrine system;Endocrine system;Cancer: specific types	ko04020//Calcium signaling pathway;ko04921//Oxytocin signaling pathway;ko04925//Aldosterone synthesis and secretion;ko05214//Glioma	K08794;K08794;K08794;K08794	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032793//positive regulation of CREB transcription factor activity;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0050766//positive regulation of phagocytosis;GO:0050773//regulation of dendrite development;GO:0060267//positive regulation of respiratory burst;GO:0071622//regulation of granulocyte chemotaxis;GO:0090023//positive regulation of neutrophil chemotaxis	--
ENSG00000183054	3.152	7.118	4.375	2.834	1.516	2.509	383.77	867.73	466.64	303.4	183.85	258.32	RGPD6	RANBP2 like and GRIP domain containing 6 [Source:HGNC Symbol;Acc:HGNC:32419]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000183060	2.437	2.327	2.856	2.319	2.942	2.756	123.67	128.47	114.84	91.34	126.64	108.21	LYSMD4	LysM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26571]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000183066	0	0	0	0	0	0	0	0	0	0	0	0	WBP2NL	WBP2 N-terminal like [Source:HGNC Symbol;Acc:HGNC:28389]	-	-	-	-	GO:0005634//nucleus;GO:0033011//perinuclear theca;GO:0036126//sperm flagellum;GO:0061827//sperm head	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0050699//WW domain binding	"GO:0007343//egg activation;GO:0035038//female pronucleus assembly;GO:0035039//male pronucleus assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051321//meiotic cell cycle"	--
ENSG00000183067	0.381	0.527	0.717	0.458	0.426	0.35	18	25	25	16	17	12	IGSF5	immunoglobulin superfamily member 5 [Source:HGNC Symbol;Acc:HGNC:5952]	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Infectious disease: bacterial	ko04530//Tight junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection	K06786;K06786	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction	-	GO:0098609//cell-cell adhesion	--
ENSG00000183072	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-5	NK2 homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2488]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001570//vasculogenesis;GO:0001947//heart looping;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003161//cardiac conduction system development;GO:0003162//atrioventricular node development;GO:0003166//bundle of His development;GO:0003168//Purkinje myocyte differentiation;GO:0003180//aortic valve morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003211//cardiac ventricle formation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003228//atrial cardiac muscle tissue development;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0003285//septum secundum development;GO:0003342//proepicardium development;GO:0003350//pulmonary myocardium development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0007512//adult heart development;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010735//positive regulation of transcription via serum response element binding;GO:0010765//positive regulation of sodium ion transport;GO:0010832//negative regulation of myotube differentiation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030878//thyroid gland development;GO:0035050//embryonic heart tube development;GO:0043066//negative regulation of apoptotic process;GO:0045214//sarcomere organization;GO:0045666//positive regulation of neuron differentiation;GO:0045823//positive regulation of heart contraction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048536//spleen development;GO:0048738//cardiac muscle tissue development;GO:0051891//positive regulation of cardioblast differentiation;GO:0055005//ventricular cardiac myofibril assembly;GO:0055007//cardiac muscle cell differentiation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0055013//cardiac muscle cell development;GO:0055014//atrial cardiac muscle cell development;GO:0055015//ventricular cardiac muscle cell development;GO:0055117//regulation of cardiac muscle contraction;GO:0060037//pharyngeal system development;GO:0060038//cardiac muscle cell proliferation;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060047//heart contraction;GO:0060048//cardiac muscle contraction;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060347//heart trabecula formation;GO:0060412//ventricular septum morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0060928//atrioventricular node cell development;GO:0060929//atrioventricular node cell fate commitment;GO:0060971//embryonic heart tube left/right pattern formation;GO:0072359//circulatory system development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1903779//regulation of cardiac conduction"	Homeobox
ENSG00000183077	14.789	16.521	13.777	15.453	16.42	17.611	258	321	175	193	256	219	AFMID	arylformamidase [Source:HGNC Symbol;Acc:HGNC:20910]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K01432;K01432;K01432	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004061//arylformamidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0034354//'de novo' NAD biosynthetic process from tryptophan	--
ENSG00000183087	16.859	17.25	9.812	12.223	13.424	9.432	877	902	377	471	590	357	GAS6	growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168]	Human Diseases	Drug resistance: antineoplastic	ko01521//EGFR tyrosine kinase inhibitor resistance	K05464	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030296//protein tyrosine kinase activator activity;GO:0030674//protein-macromolecule adaptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0048018//receptor ligand activity	"GO:0001764//neuron migration;GO:0001934//positive regulation of protein phosphorylation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0003104//positive regulation of glomerular filtration;GO:0006468//protein phosphorylation;GO:0006909//phagocytosis;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007596//blood coagulation;GO:0009267//cellular response to starvation;GO:0010628//positive regulation of gene expression;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0019079//viral genome replication;GO:0031100//animal organ regeneration;GO:0031589//cell-substrate adhesion;GO:0032008//positive regulation of TOR signaling;GO:0032148//activation of protein kinase B activity;GO:0032689//negative regulation of interferon-gamma production;GO:0032692//negative regulation of interleukin-1 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032825//positive regulation of natural killer cell differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035457//cellular response to interferon-alpha;GO:0035754//B cell chemotaxis;GO:0040008//regulation of growth;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043277//apoptotic cell clearance;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043491//protein kinase B signaling;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0046827//positive regulation of protein export from nucleus;GO:0048146//positive regulation of fibroblast proliferation;GO:0050766//positive regulation of phagocytosis;GO:0051897//positive regulation of protein kinase B signaling;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070168//negative regulation of biomineral tissue development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070588//calcium ion transmembrane transport;GO:0071307//cellular response to vitamin K;GO:0071333//cellular response to glucose stimulus;GO:0071363//cellular response to growth factor stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:0072659//protein localization to plasma membrane;GO:0085029//extracellular matrix assembly;GO:0097028//dendritic cell differentiation;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:1900142//negative regulation of oligodendrocyte apoptotic process;GO:2000270//negative regulation of fibroblast apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:2000533//negative regulation of renal albumin absorption;GO:2000669//negative regulation of dendritic cell apoptotic process"	--
ENSG00000183090	0.007	0.021	0	0	0.008	0	1	3	0	0	1	0	FREM3	FRAS1 related extracellular matrix 3 [Source:HGNC Symbol;Acc:HGNC:25172]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0046872//metal ion binding	GO:0007154//cell communication;GO:0007155//cell adhesion	--
ENSG00000183091	0.099	0.089	0.262	0.171	0.161	0.183	24	17	19	20	32	26	NEB	nebulin [Source:HGNC Symbol;Acc:HGNC:7720]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0043292//contractile fiber;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0051015//actin filament binding	GO:0007517//muscle organ development;GO:0007525//somatic muscle development;GO:0030832//regulation of actin filament length;GO:0071691//cardiac muscle thin filament assembly	--
ENSG00000183092	0.109	0.109	0.073	0.321	0.137	0.025	6	6	3	13	7	1	BEGAIN	brain enriched guanylate kinase associated [Source:HGNC Symbol;Acc:HGNC:24163]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0016301//kinase activity	GO:0016310//phosphorylation;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000183098	8.883	8.741	5.353	10.465	9.857	8.081	1312	1221	584	1017	1180	797	GPC6	glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0045202//synapse;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix	"GO:0005515//protein binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0009966//regulation of signal transduction;GO:0016477//cell migration;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0098696//regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;GO:0099560//synaptic membrane adhesion;GO:1905475//regulation of protein localization to membrane;GO:1905606//regulation of presynapse assembly"	--
ENSG00000183111	21.526	21.212	23.744	19.791	21.75	23.311	2207	2186	1798	1503	1884	1739	ARHGEF37	Rho guanine nucleotide exchange factor 37 [Source:HGNC Symbol;Acc:HGNC:34430]	-	-	-	-	GO:0005737//cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000183114	0.158	0.02	0.027	0.053	0.093	0.054	8	1	1	2	4	2	FAM43B	family with sequence similarity 43 member B [Source:HGNC Symbol;Acc:HGNC:31791]	-	-	-	-	-	-	-	--
ENSG00000183117	0.031	0.047	0	0	0	0.016	7	12	0	0	0	3	CSMD1	CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0001964//startle response;GO:0007613//memory;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0035846//oviduct epithelium development;GO:0042593//glucose homeostasis;GO:0060745//mammary gland branching involved in pregnancy;GO:1990708//conditioned place preference	--
ENSG00000183128	0	0	0	0	0	0	0	0	0	0	0	0	CALHM3	calcium homeostasis modulator 3 [Source:HGNC Symbol;Acc:HGNC:23458]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005244//voltage-gated ion channel activity;GO:0005261//cation channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0015867//ATP transport;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0051291//protein heterooligomerization;GO:0098655//cation transmembrane transport	--
ENSG00000183134	0	0.033	0.023	0.045	0.059	0	0	2	1	2	3	0	PTGDR2	prostaglandin D2 receptor 2 [Source:HGNC Symbol;Acc:HGNC:4502]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0001785//prostaglandin J receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004956//prostaglandin D receptor activity;GO:0004958//prostaglandin F receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0019722//calcium-mediated signaling;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:2000255//negative regulation of male germ cell proliferation	--
ENSG00000183137	3.561	2.627	2.357	1.804	2.348	3.392	186	122	87.03	80	114	111	CEP57L1	centrosomal protein 57 like 1 [Source:HGNC Symbol;Acc:HGNC:21561]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0043015//gamma-tubulin binding	GO:0008150//biological_process	--
ENSG00000183145	0.023	0.069	0	0	0.054	0.063	1	3	0	0	2	2	RIPPLY3	ripply transcriptional repressor 3 [Source:HGNC Symbol;Acc:HGNC:3047]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007507//heart development;GO:0008150//biological_process;GO:0008285//negative regulation of cell population proliferation;GO:0009880//embryonic pattern specification;GO:0060037//pharyngeal system development	--
ENSG00000183148	0.061	0	0.044	0	0	0	4.94	0	2.63	0	0	0	ANKRD20A2P	"ankyrin repeat domain 20 family member A2, pseudogene [Source:HGNC Symbol;Acc:HGNC:31979]"	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183150	0.083	0.165	0.075	0	0.164	0.076	3	6	2	0	5	2	GPR19	G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000183153	0.283	0.505	0.399	0.637	0.67	0.6	24	43	25	40	48	37	GJD3	gap junction protein delta 3 [Source:HGNC Symbol;Acc:HGNC:19147]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005216//ion channel activity;GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0009749//response to glucose;GO:0010459//negative regulation of heart rate;GO:0016264//gap junction assembly;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0086053//AV node cell to bundle of His cell communication by electrical coupling;GO:1901845//negative regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1903780//negative regulation of cardiac conduction	--
ENSG00000183155	4.452	4.044	3.39	3.965	3.33	5.035	288	263	162	190	182	237	RABIF	RAB interacting factor [Source:HGNC Symbol;Acc:HGNC:9797]	-	-	-	-	GO:0005829//cytosol;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006892//post-Golgi vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0050790//regulation of catalytic activity;GO:0061025//membrane fusion	--
ENSG00000183160	0	0.018	0	0	0.021	0	0	1	0	0	1	0	TMEM119	transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0001958//endochondral ossification;GO:0007283//spermatogenesis;GO:0010628//positive regulation of gene expression;GO:0010832//negative regulation of myotube differentiation;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0033690//positive regulation of osteoblast proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045779//negative regulation of bone resorption;GO:0048515//spermatid differentiation;GO:1903012//positive regulation of bone development	--
ENSG00000183161	6.592	7.273	6.922	6.507	6.433	7.872	450	499	349	329	371	391	FANCF	FA complementation group F [Source:HGNC Symbol;Acc:HGNC:3587]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10893	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0008150//biological_process;GO:0036297//interstrand cross-link repair	--
ENSG00000183166	0.006	0.006	0	0	0.007	0	1	1	0	0	1	0	CALN1	calneuron 1 [Source:HGNC Symbol;Acc:HGNC:13248]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000183172	12.683	14.934	14.529	19.751	15.641	13.995	363	427	310	378	382	273	SMDT1	single-pass membrane protein with aspartate rich tail 1 [Source:HGNC Symbol;Acc:HGNC:25055]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:1990246//uniplex complex	GO:0005515//protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0036444//calcium import into the mitochondrion;GO:0051560//mitochondrial calcium ion homeostasis	--
ENSG00000183185	0	0	0	0	0	0.043	0	0	0	0	0	2	GABRR3	gamma-aminobutyric acid type A receptor subunit rho3 [Source:HGNC Symbol;Acc:HGNC:17969]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05190;K05190;K05190;K05190;K05190	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:1902476//chloride transmembrane transport	--
ENSG00000183186	0.467	0.325	0.695	0.672	0.902	0.641	30	21	33	32	49	30	C2CD4C	C2 calcium dependent domain containing 4C [Source:HGNC Symbol;Acc:HGNC:29417]	-	-	-	-	GO:0005829//cytosol	-	-	--
ENSG00000183196	1.209	1.166	1.291	0.745	0.928	1.091	164	138	123	84	97	123	CHST6	carbohydrate sulfotransferase 6 [Source:HGNC Symbol;Acc:HGNC:6938]	Metabolism	Glycan biosynthesis and metabolism	ko00533//Glycosaminoglycan biosynthesis - keratan sulfate	K09671	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0045130//keratan sulfotransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0018146//keratan sulfate biosynthetic process	--
ENSG00000183206	0	0	0	0	0	0	0	0	0	0	0	0	POTEC	POTE ankyrin domain family member C [Source:HGNC Symbol;Acc:HGNC:33894]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183207	43.346	47.246	44.87	49.963	48.131	43.145	1382	1521	1054	1179	1291	1006	RUVBL2	RuvB like AAA ATPase 2 [Source:HGNC Symbol;Acc:HGNC:10475]	-	-	-	-	GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0031011//Ino80 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0070062//extracellular exosome;GO:0071339//MLL1 complex;GO:0097255//R2TP complex;GO:0101031//chaperone complex;GO:0120293//dynein axonemal particle;GO:1990062//RPAP3/R2TP/prefoldin-like complex;GO:1990904//ribonucleoprotein complex	"GO:0000166//nucleotide binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001094//TFIID-class transcription factor complex binding;GO:0003678//DNA helicase activity;GO:0003714//transcription corepressor activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008013//beta-catenin binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017025//TBP-class protein binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0051082//unfolded protein binding;GO:0051117//ATPase binding;GO:0140585//promoter-enhancer loop anchoring activity"	"GO:0000492//box C/D snoRNP assembly;GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006457//protein folding;GO:0006974//cellular response to DNA damage stimulus;GO:0016573//histone acetylation;GO:0032508//DNA duplex unwinding;GO:0033044//regulation of chromosome organization;GO:0034644//cellular response to UV;GO:0035066//positive regulation of histone acetylation;GO:0040008//regulation of growth;GO:0042766//nucleosome mobilization;GO:0042981//regulation of apoptotic process;GO:0043486//histone exchange;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045739//positive regulation of DNA repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0050821//protein stabilization;GO:0051726//regulation of cell cycle;GO:0060382//regulation of DNA strand elongation;GO:0071169//establishment of protein localization to chromatin;GO:0071392//cellular response to estradiol stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904507//positive regulation of telomere maintenance in response to DNA damage;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000183208	0.593	0.657	0.624	0.569	0.704	0.501	63.33	71	50.28	45	64.32	39	GDPGP1	GDP-D-glucose phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:34360]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0080048//GDP-D-glucose phosphorylase activity	GO:0006006//glucose metabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000183230	0.461	0.316	0.261	0.463	0.664	0.372	90	51	31	68	82	54	CTNNA3	catenin alpha 3 [Source:HGNC Symbol;Acc:HGNC:2511]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types;Immune system;Infectious disease: bacterial;Cardiovascular disease;Cellular community - eukaryotes;Cancer: specific types	ko05200//Pathways in cancer;ko04390//Hippo signaling pathway;ko05226//Gastric cancer;ko04670//Leukocyte transendothelial migration;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04520//Adherens junction;ko05213//Endometrial cancer	K05691;K05691;K05691;K05691;K05691;K05691;K05691;K05691	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005916//fascia adherens;GO:0030027//lamellipodium;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0016477//cell migration;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0090136//epithelial cell-cell adhesion;GO:0098609//cell-cell adhesion;GO:0098911//regulation of ventricular cardiac muscle cell action potential	--
ENSG00000183246	0	0.017	0	0	0	0	0	2.06	0	0	0	0	RIMBP3C	RIMS binding protein 3C [Source:HGNC Symbol;Acc:HGNC:33892]	-	-	-	-	GO:0002177//manchette;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0030156//benzodiazepine receptor binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008150//biological_process;GO:0009566//fertilization;GO:0030154//cell differentiation	--
ENSG00000183248	2.436	2.953	2.703	3.133	3.628	3.456	218	275	185	215	284	233	PRR36	proline rich 36 [Source:HGNC Symbol;Acc:HGNC:26172]	-	-	-	-	-	-	-	--
ENSG00000183251	0	0	0	0	0	0	0	0	0	0	0	0	OR51B4	olfactory receptor family 51 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:14708]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183255	218.643	221.702	204.859	208.612	203.089	212.076	11731	11975	8132	8291	9217	8292	PTTG1IP	PTTG1 interacting protein [Source:HGNC Symbol;Acc:HGNC:13524]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0002039//p53 binding;GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0006606//protein import into nucleus;GO:0031398//positive regulation of protein ubiquitination;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1903364//positive regulation of cellular protein catabolic process"	--
ENSG00000183258	43.792	46.054	48.456	50.974	53.478	48.153	1400	1557	1253	1286	1366	1196	DDX41	DEAD-box helicase 41 [Source:HGNC Symbol;Acc:HGNC:18674]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008283//cell population proliferation;GO:0008380//RNA splicing;GO:0030154//cell differentiation"	--
ENSG00000183260	0.711	0.547	0.788	0.567	0.995	1.2	22	17	18	13	26	27	ABHD16B	abhydrolase domain containing 16B [Source:HGNC Symbol;Acc:HGNC:16128]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane	GO:0004620//phospholipase activity;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity	GO:0006660//phosphatidylserine catabolic process;GO:0052651//monoacylglycerol catabolic process;GO:0098734//macromolecule depalmitoylation	--
ENSG00000183269	0	0	0	0	0	0	0	0	0	0	0	0	OR52E8	olfactory receptor family 52 subfamily E member 8 [Source:HGNC Symbol;Acc:HGNC:15217]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183273	2.152	1.604	1.922	0.566	0.82	0.833	55	40	33	12	15	13	CCDC60	coiled-coil domain containing 60 [Source:HGNC Symbol;Acc:HGNC:28610]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183281	0.651	0.855	0.887	0.469	0.442	0.581	31.49	30.18	28.88	8.1	21.92	13.53	PLGLB1	plasminogen like B1 [Source:HGNC Symbol;Acc:HGNC:9072]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01315;K01315;K01315;K01315	GO:0005576//extracellular region	GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding	GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity	--
ENSG00000183283	91.696	95.359	98.183	103.076	104.984	105.254	3815	4003	3029	3218	3612	3081	DAZAP2	DAZ associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2684]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0050699//WW domain binding	GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000183287	0.502	0.777	0.53	0.957	0.508	1.152	52	72	39	76	57	78	CCBE1	collagen and calcium binding EGF domains 1 [Source:HGNC Symbol;Acc:HGNC:29426]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0002020//protease binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005518//collagen binding	GO:0001525//angiogenesis;GO:0001945//lymph vessel development;GO:0001946//lymphangiogenesis;GO:0002040//sprouting angiogenesis;GO:0003016//respiratory system process;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010595//positive regulation of endothelial cell migration;GO:0010954//positive regulation of protein processing;GO:0030324//lung development;GO:0045766//positive regulation of angiogenesis;GO:0048845//venous blood vessel morphogenesis;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:1901492//positive regulation of lymphangiogenesis	--
ENSG00000183291	100.113	97.576	94.287	82.931	81.455	93.921	3060	2985	2140	1890	2111	2103	SELENOF	selenoprotein F [Source:HGNC Symbol;Acc:HGNC:17705]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity	GO:0035092//sperm chromatin condensation;GO:0051084//'de novo' posttranslational protein folding;GO:0098869//cellular oxidant detoxification	--
ENSG00000183303	0	0	0	0	0	0	0	0	0	0	0	0	OR5P2	olfactory receptor family 5 subfamily P member 2 [Source:HGNC Symbol;Acc:HGNC:14783]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183304	0	0	0	0	0	0	0	0	0	0	0	0	FAM9A	family with sequence similarity 9 member A [Source:HGNC Symbol;Acc:HGNC:18403]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0007286//spermatid development;GO:0051321//meiotic cell cycle	--
ENSG00000183305	0.132	0.12	0.134	0.241	0.039	0.929	3.23	3.82	1.34	6.74	0.45	12	MAGEA2B	MAGE family member A2B [Source:HGNC Symbol;Acc:HGNC:19340]	-	-	-	-	GO:0005634//nucleus;GO:0016605//PML body	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0033234//negative regulation of protein sumoylation;GO:0044257//cellular protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0072331//signal transduction by p53 class mediator;GO:0090398//cellular senescence;GO:1901984//negative regulation of protein acetylation	--
ENSG00000183307	0.049	0.009	0.016	0	0.014	0	4	1	1	0	1	0	TMEM121B	transmembrane protein 121B [Source:HGNC Symbol;Acc:HGNC:1844]	-	-	-	-	-	-	-	--
ENSG00000183309	7.43	7.352	6.954	5.53	6.717	8.146	760	747	575	472	586	577	ZNF623	zinc finger protein 623 [Source:HGNC Symbol;Acc:HGNC:29084]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000183310	0	0	0	0	0	0	0	0	0	0	0	0	OR2T34	olfactory receptor family 2 subfamily T member 34 [Source:HGNC Symbol;Acc:HGNC:31256]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183313	0	0	0	0	0	0	0	0	0	0	0	0	OR52L1	olfactory receptor family 52 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:14785]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183317	0.207	0.139	0.095	0.244	0.135	0.296	8	7	8	6	13	3	EPHA10	EPH receptor A10 [Source:HGNC Symbol;Acc:HGNC:19987]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043235//receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0008150//biological_process;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000183318	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE4	speedy/RINGO cell cycle regulator family member E4 [Source:HGNC Symbol;Acc:HGNC:35463]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000183323	2.479	1.66	1.736	1.379	1.933	1.544	137	102	97	64	89	58	CCDC125	coiled-coil domain containing 125 [Source:HGNC Symbol;Acc:HGNC:28924]	-	-	-	-	GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0035024//negative regulation of Rho protein signal transduction;GO:0090630//activation of GTPase activity;GO:2000145//regulation of cell motility;GO:2000146//negative regulation of cell motility	--
ENSG00000183324	0	0.104	0	0	0.124	0	0	2	0	0	2	0	REC114	REC114 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:25065]	-	-	-	-	-	GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0051321//meiotic cell cycle	--
ENSG00000183336	13.474	10.188	13.612	7.549	11.234	11.253	111.51	84.54	82.58	46.28	78.55	67.76	BOLA2	bolA family member 2 [Source:HGNC Symbol;Acc:HGNC:29488]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990229//iron-sulfur cluster assembly complex	"GO:0005515//protein binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006879//cellular iron ion homeostasis;GO:0016226//iron-sulfur cluster assembly;GO:0044571//[2Fe-2S] cluster assembly;GO:0045454//cell redox homeostasis;GO:0055072//iron ion homeostasis;GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000183337	10.697	10.42	9.718	8.49	10.492	9.58	1315	1328	937	783	1108	899	BCOR	BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0140261//BCOR complex	GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000415//negative regulation of histone H3-K36 methylation;GO:0001835//blastocyst hatching;GO:0006325//chromatin organization;GO:0007507//heart development;GO:0030502//negative regulation of bone mineralization;GO:0035518//histone H2A monoubiquitination;GO:0042476//odontogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0060021//roof of mouth development;GO:0065001//specification of axis polarity;GO:0070171//negative regulation of tooth mineralization"	--
ENSG00000183340	2.426	2.719	2.287	2.094	1.981	1.498	158	178	110	101	109	71	JRKL	JRK like [Source:HGNC Symbol;Acc:HGNC:6200]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding	GO:0007417//central nervous system development	--
ENSG00000183346	0.772	0.966	0.891	0.925	0.845	0.51	27	34	23	24	25	13	CABCOCO1	ciliary associated calcium binding coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28678]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000183347	0	0	0.042	0.014	0.024	0.028	0	0	3	1	2	2	GBP6	guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395]	-	-	-	-	GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006955//immune response;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0050830//defense response to Gram-positive bacterium;GO:0071346//cellular response to interferon-gamma	--
ENSG00000183354	4.338	2.522	3.076	1.823	2.525	2.59	496	303	256	174	242	220	KIAA2026	KIAA2026 [Source:HGNC Symbol;Acc:HGNC:23378]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183378	0	0.033	0	0	0	0.046	0	1	0	0	0	1	OVCH2	ovochymase 2 [Source:HGNC Symbol;Acc:HGNC:29970]	-	-	-	-	-	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0009566//fertilization	--
ENSG00000183379	0.04	0	0.027	0	0	0.027	2	0	1	0	0	1	SYNDIG1L	synapse differentiation inducing 1 like [Source:HGNC Symbol;Acc:HGNC:32388]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000183386	4.425	5.706	3.272	5.66	5.031	4.882	152	197	83	144	146	122	FHL3	four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704]	-	-	-	-	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0030018//Z disc	GO:0003712//transcription coregulator activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007517//muscle organ development;GO:0030036//actin cytoskeleton organization"	--
ENSG00000183389	0	0	0	0	0	0	0	0	0	0	0	0	OR56A4	olfactory receptor family 56 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:14791]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183395	0	0	0	0	0	0	0	0	0	0	0	0	PMCH	pro-melanin concentrating hormone [Source:HGNC Symbol;Acc:HGNC:9109]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05229	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0045202//synapse	GO:0005179//hormone activity;GO:0030354//melanin-concentrating hormone activity;GO:0031777//type 1 melanin-concentrating hormone receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007283//spermatogenesis;GO:0007631//feeding behavior;GO:0030154//cell differentiation	--
ENSG00000183396	0	0	0	0	0	0	0	0	0	0	0	0	TMEM89	transmembrane protein 89 [Source:HGNC Symbol;Acc:HGNC:32372]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000183397	0	0.147	0	0	0	0	0	2	0	0	0	0	C19orf71	chromosome 19 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:34496]	-	-	-	-	-	-	-	--
ENSG00000183401	9.398	11.238	11.366	8.563	11.662	8.415	146	176	129	99	140	108	CCDC159	coiled-coil domain containing 159 [Source:HGNC Symbol;Acc:HGNC:26996]	-	-	-	-	-	-	-	--
ENSG00000183421	3.709	4.456	4.023	4.558	4.835	4.738	296	357	237	269	328	276	RIPK4	receptor interacting serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:496]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0002009//morphogenesis of an epithelium;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000183423	0.092	0.182	0.125	0.267	0.337	0.199	7	14	7	15	21.87	11	LRIT3	"leucine rich repeat, Ig-like and transmembrane domains 3 [Source:HGNC Symbol;Acc:HGNC:24783]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005515//protein binding	GO:0007601//visual perception;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0050896//response to stimulus	--
ENSG00000183426	4.353	4.039	6.582	3.612	4.459	4.649	76.72	67.87	89.57	52.09	63.11	61.84	NPIPA1	nuclear pore complex interacting protein family member A1 [Source:HGNC Symbol;Acc:HGNC:7909]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	-	GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000183431	17.38	16.582	16.449	15.65	14.606	15.048	1000	959	699	667	710	630	SF3A3	splicing factor 3a subunit 3 [Source:HGNC Symbol;Acc:HGNC:10767]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12827	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:1903241//U2-type prespliceosome assembly"	--
ENSG00000183434	0	0	0	0	0	0	0	0	0	0	0	0	TFDP3	transcription factor Dp family member 3 [Source:HGNC Symbol;Acc:HGNC:24603]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity	"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0051726//regulation of cell cycle;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	E2F
ENSG00000183439	2.216	1.784	1.355	1.585	1.547	2.133	94	76	44	53	60	72	TRIM61	tripartite motif containing 61 [Source:HGNC Symbol;Acc:HGNC:24339]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000183454	0.009	0.021	0.04	0.041	0.026	0.009	1	4	4	6	2	2	GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Immune disease;Substance dependence;Neurodegenerative disease;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209;K05209	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097060//synaptic membrane;GO:0098794//postsynapse;GO:0098839//postsynaptic density membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015276//ligand-gated ion channel activity;GO:0022849//glutamate-gated calcium ion channel activity;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0099094//ligand-gated cation channel activity	"GO:0001964//startle response;GO:0001975//response to amphetamine;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0007611//learning or memory;GO:0007612//learning;GO:0007613//memory;GO:0008542//visual learning;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0019233//sensory perception of pain;GO:0019722//calcium-mediated signaling;GO:0022008//neurogenesis;GO:0030431//sleep;GO:0033058//directional locomotion;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0040011//locomotion;GO:0042177//negative regulation of protein catabolic process;GO:0042391//regulation of membrane potential;GO:0042417//dopamine metabolic process;GO:0042428//serotonin metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0045471//response to ethanol;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0070588//calcium ion transmembrane transport;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098976//excitatory chemical synaptic transmission;GO:1903539//protein localization to postsynaptic membrane;GO:1904062//regulation of cation transmembrane transport;GO:2000463//positive regulation of excitatory postsynaptic potential"	--
ENSG00000183463	0	0	0	0	0	0	0	0	0	0	0	0	URAD	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase [Source:HGNC Symbol;Acc:HGNC:17785]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K13485;K13485	GO:0005575//cellular_component;GO:0005777//peroxisome	GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity;GO:0051997//2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity	GO:0000255//allantoin metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0008150//biological_process;GO:0019628//urate catabolic process	--
ENSG00000183474	7.651	5.004	5.572	5.637	5.294	6.31	297.14	223.02	166.74	154.77	209.24	183.62	GTF2H2C	GTF2H2 family member C [Source:HGNC Symbol;Acc:HGNC:31394]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Transcription;Replication and repair	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K03142;K03142;K03142	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005675//transcription factor TFIIH holo complex;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus"	--
ENSG00000183475	4.432	4.968	4.642	4.947	5.445	4.845	448	463	312	305	374	340	ASB7	ankyrin repeat and SOCS box containing 7 [Source:HGNC Symbol;Acc:HGNC:17182]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0043687//post-translational protein modification	--
ENSG00000183476	0.045	0.089	0.03	0.06	0	0.184	2	4	1	2	0	6	SH2D7	SH2 domain containing 7 [Source:HGNC Symbol;Acc:HGNC:34549]	-	-	-	-	-	-	-	--
ENSG00000183479	0.182	0.224	0.124	0.248	0.036	0	9.47	11.44	4.75	9.55	1.35	0	TREX2	three prime repair exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:12270]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008853//exodeoxyribonuclease III activity;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	"GO:0000738//DNA catabolic process, exonucleolytic;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus"	--
ENSG00000183484	0.054	0	0.023	0.047	0	0	4	0	1	2	0	0	GPR132	G protein-coupled receptor 132 [Source:HGNC Symbol;Acc:HGNC:17482]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle	--
ENSG00000183486	0.135	0.314	0	0.038	0.143	0	5	7	0	2	2	0	MX2	MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral	ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05164//Influenza A;ko05160//Hepatitis C;ko05162//Measles	K14754;K14754;K14754;K14754;K14754	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding	GO:0002376//immune system process;GO:0006952//defense response;GO:0009615//response to virus;GO:0015031//protein transport;GO:0035455//response to interferon-alpha;GO:0045087//innate immune response;GO:0046822//regulation of nucleocytoplasmic transport;GO:0051028//mRNA transport;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle	--
ENSG00000183495	6.788	6.283	6.678	6.488	6.597	6.66	1315	1340	962	882	1079	919	EP400	E1A binding protein p400 [Source:HGNC Symbol;Acc:HGNC:11958]	-	-	-	-	GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0035267//NuA4 histone acetyltransferase complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0140658//ATP-dependent chromatin remodeler activity;GO:1990405//protein antigen binding	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0016573//histone acetylation;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000183496	3.154	3.472	2.052	1.554	2.314	2.478	224	252	109	82	143	128	MEX3B	mex-3 RNA binding family member B [Source:HGNC Symbol;Acc:HGNC:25297]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006468//protein phosphorylation;GO:0046777//protein autophosphorylation	--
ENSG00000183508	7.896	8.373	8.832	6.872	7.782	7.711	926	987	765	597	771	658	TENT5C	terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:1990817//RNA adenylyltransferase activity	GO:0001701//in utero embryonic development;GO:0045596//negative regulation of cell differentiation;GO:0048255//mRNA stabilization	--
ENSG00000183513	10.214	12.276	12.17	9.965	11.528	11.53	375	453	330	271	352	308	COA5	cytochrome c oxidase assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:33848]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18178	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000183520	6.649	7.208	7.26	5.534	6.262	5.47	279	304	225	172	222	167	UTP11	UTP11 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0007399//nervous system development;GO:0043065//positive regulation of apoptotic process	--
ENSG00000183527	16.003	16.292	14.635	17.353	15.717	18.615	336	353	220	255	267	275	PSMG1	proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0060090//molecular adaptor activity;GO:0070628//proteasome binding	GO:0021930//cerebellar granule cell precursor proliferation;GO:0043248//proteasome assembly;GO:0051131//chaperone-mediated protein complex assembly;GO:0080129//proteasome core complex assembly	--
ENSG00000183530	4.993	3.504	3.527	2.549	3.268	3.709	1094	791	585	424	620	606	PRR14L	proline rich 14 like [Source:HGNC Symbol;Acc:HGNC:28738]	-	-	-	-	-	-	-	--
ENSG00000183542	0	0	0	0	0	0	0	0	0	0	0	0	KLRC4	killer cell lectin like receptor C4 [Source:HGNC Symbol;Acc:HGNC:6377]	Organismal Systems	Immune system	ko04612//Antigen processing and presentation	K24234	GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity	GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000183549	0.101	0.098	0.173	0.129	0.112	0.117	3	4	3	3	3	2	ACSM5	acyl-CoA synthetase medium chain family member 5 [Source:HGNC Symbol;Acc:HGNC:26060]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0015645//fatty acid ligase activity;GO:0016874//ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000183559	0	0	0	0	0	0	0	0	0	0	0	0	C10orf120	chromosome 10 open reading frame 120 [Source:HGNC Symbol;Acc:HGNC:25707]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183560	0	0	0	0	0	0	0	0	0	0	0	0	IZUMO1R	"IZUMO1 receptor, JUNO [Source:HGNC Symbol;Acc:HGNC:32565]"	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0035036//sperm-egg recognition	--
ENSG00000183569	0.668	0.951	1.122	0.596	0.869	0.495	21	21.08	20	10	18	10.05	SERHL2	serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0016787//hydrolase activity	GO:0008150//biological_process	--
ENSG00000183570	2.475	2.106	3.422	3.098	2.711	3.073	102	91	110	102	96	96	PCBP3	poly(rC) binding protein 3 [Source:HGNC Symbol;Acc:HGNC:8651]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0010468//regulation of gene expression;GO:0016071//mRNA metabolic process;GO:0051252//regulation of RNA metabolic process	--
ENSG00000183571	0	0	0	0.213	0	0	0	0	0	2	0	0	PGPEP1L	pyroglutamyl-peptidase I like [Source:HGNC Symbol;Acc:HGNC:27080]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016920//pyroglutamyl-peptidase activity	GO:0006508//proteolysis	--
ENSG00000183576	43.687	43.714	41.529	32.466	35.286	36.435	2542	2531	1783	1384	1688	1521	SETD3	"SET domain containing 3, actin histidine methyltransferase [Source:HGNC Symbol;Acc:HGNC:20493]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018064//protein-L-histidine N-tele-methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0006479//protein methylation;GO:0006996//organelle organization;GO:0010452//histone H3-K36 methylation;GO:0018021//peptidyl-histidine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0030047//actin modification;GO:0032259//methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051149//positive regulation of muscle cell differentiation;GO:0051568//histone H3-K4 methylation;GO:0070472//regulation of uterine smooth muscle contraction"	--
ENSG00000183578	0.346	0.155	0.211	0.28	0.181	0.327	15	6	6	8	7	10	TNFAIP8L3	TNF alpha induced protein 8 like 3 [Source:HGNC Symbol;Acc:HGNC:20620]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0008526//phosphatidylinositol transfer activity;GO:0035091//phosphatidylinositol binding	GO:0006644//phospholipid metabolic process;GO:0006869//lipid transport;GO:0015914//phospholipid transport;GO:0019216//regulation of lipid metabolic process;GO:0042981//regulation of apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048017//inositol lipid-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0120009//intermembrane lipid transfer	--
ENSG00000183579	4.616	4.915	4.408	4.802	4.235	4.686	658	603.03	464	507	510	486	ZNRF3	zinc and ring finger 3 [Source:HGNC Symbol;Acc:HGNC:18126]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K16273	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004842//ubiquitin-protein transferase activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0030178//negative regulation of Wnt signaling pathway;GO:0038018//Wnt receptor catabolic process;GO:0060173//limb development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0072089//stem cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000183580	6.219	6.111	6.627	6.556	6.324	6.932	570	573	439	449	472	442	FBXL7	F-box and leucine rich repeat protein 7 [Source:HGNC Symbol;Acc:HGNC:13604]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0000278//mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051301//cell division	--
ENSG00000183597	25.478	31.22	31.023	28.611	26.331	26.031	1089	1149	852	763	852	799	TANGO2	transport and golgi organization 2 homolog [Source:HGNC Symbol;Acc:HGNC:25439]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol	-	GO:0007030//Golgi organization;GO:0009306//protein secretion	--
ENSG00000183598	0	0	0	0	0	0	0	0	0	0	0	0	H3C13	H3 clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:25311]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly	--
ENSG00000183605	9.987	9.38	7.499	10.487	9.694	10.551	284	271	158	234	232	219	SFXN4	sideroflexin 4 [Source:HGNC Symbol;Acc:HGNC:16088]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0015075//ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:1990542//mitochondrial transmembrane transport	--
ENSG00000183607	0	0	0	0	0	0	0	0	0	0	0	0	GKN2	gastrokine 2 [Source:HGNC Symbol;Acc:HGNC:24588]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0045178//basal part of cell	GO:0005515//protein binding	GO:0009617//response to bacterium;GO:0042127//regulation of cell population proliferation	--
ENSG00000183615	0.051	0.253	0.483	0.481	0.362	0.14	1	5	7	7	6	2	FAM167B	family with sequence similarity 167 member B [Source:HGNC Symbol;Acc:HGNC:28133]	-	-	-	-	-	-	-	--
ENSG00000183617	14.087	15.62	13.348	17.128	18.677	16.783	177	198	124	160	199	154	MRPL54	mitochondrial ribosomal protein L54 [Source:HGNC Symbol;Acc:HGNC:16685]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0032543//mitochondrial translation	--
ENSG00000183621	1.749	1.947	1.341	1.465	1.465	1.946	109	123	64	68	78	85	ZNF438	zinc finger protein 438 [Source:HGNC Symbol;Acc:HGNC:21029]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000183624	13.247	14.032	13.148	15.778	14.858	14.456	530	536	376	471	491	388	HMCES	"5-hydroxymethylcytosine binding, ES cell specific [Source:HGNC Symbol;Acc:HGNC:24446]"	-	-	-	-	GO:0005657//replication fork;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0018142//protein-DNA covalent cross-linking;GO:0045830//positive regulation of isotype switching;GO:0097681//double-strand break repair via alternative nonhomologous end joining	--
ENSG00000183625	0	0	0	0	0	0	0	0	0	0	0	0	CCR3	C-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:1604]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04178;K04178;K04178;K04178;K04178;K04178	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0001938//positive regulation of endothelial cell proliferation;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0045766//positive regulation of angiogenesis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000183628	9.236	9.725	9.818	11.261	11.098	9.099	253.62	264.4	189.38	221.9	246.66	190.65	DGCR6	DiGeorge syndrome critical region gene 6 [Source:HGNC Symbol;Acc:HGNC:2846]	-	-	-	-	GO:0005634//nucleus;GO:0031012//extracellular matrix	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis	--
ENSG00000183629	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA8G	golgin A8 family member G [Source:HGNC Symbol;Acc:HGNC:25328]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network	GO:0005515//protein binding	-	--
ENSG00000183631	0	0	0	0	0	0	0	0	0	0	0	0	PRR32	proline rich 32 [Source:HGNC Symbol;Acc:HGNC:34498]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183632	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3	TP53 target 3 [Source:HGNC Symbol;Acc:HGNC:30759]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000183638	0.006	0	0	0.024	0.007	0.008	1	0	0	3	1	1	RP1L1	RP1 like 1 [Source:HGNC Symbol;Acc:HGNC:15946]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0032391//photoreceptor connecting cilium;GO:0042995//cell projection	-	GO:0007601//visual perception;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:0035556//intracellular signal transduction;GO:0042461//photoreceptor cell development;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye	--
ENSG00000183640	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP8-1	keratin associated protein 8-1 [Source:HGNC Symbol;Acc:HGNC:18935]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000183644	1.839	1.427	0.154	0.25	0.272	0.181	29	22	3	4	4	2	HOATZ	HOATZ cilia and flagella associated protein [Source:HGNC Symbol;Acc:HGNC:25061]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0042995//cell projection	-	GO:0007283//spermatogenesis;GO:0030317//flagellated sperm motility;GO:0035082//axoneme assembly;GO:0060271//cilium assembly	--
ENSG00000183647	1.119	0.927	0.689	0.563	0.997	0.646	61	42	39	28	43	27	ZNF530	zinc finger protein 530 [Source:HGNC Symbol;Acc:HGNC:29297]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000183648	27.989	27.563	28.311	39.145	21.165	30.861	185	184	140	192	119	149	NDUFB1	NADH:ubiquinone oxidoreductase subunit B1 [Source:HGNC Symbol;Acc:HGNC:7695]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957;K03957	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000183654	0.082	0.055	0.037	0.496	0.195	0.038	3	2	1	7	2	1	MARCHF11	membrane associated ring-CH-type finger 11 [Source:HGNC Symbol;Acc:HGNC:33609]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000183655	2.179	2.51	2.271	2.389	1.923	2.523	165	191	127	134	123	139	KLHL25	kelch like family member 25 [Source:HGNC Symbol;Acc:HGNC:25732]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0006446//regulation of translational initiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000183662	0.025	0.1	0.034	0.136	0.149	0.035	1	4	1	4	5	1	TAFA1	TAFA chemokine like family member 1 [Source:HGNC Symbol;Acc:HGNC:21587]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0007165//signal transduction;GO:0010469//regulation of signaling receptor activity;GO:0014016//neuroblast differentiation;GO:1902692//regulation of neuroblast proliferation	--
ENSG00000183665	3.845	4.325	3.904	3.539	3.62	4.143	176	194	132	120	140	138	TRMT12	tRNA methyltransferase 12 homolog [Source:HGNC Symbol;Acc:HGNC:26091]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008175//tRNA methyltransferase activity;GO:0016740//transferase activity;GO:0102522//tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	GO:0008033//tRNA processing;GO:0030488//tRNA methylation	--
ENSG00000183668	0	0	0	0	0	0	0	0	0	0	0	0	PSG9	pregnancy specific beta-1-glycoprotein 9 [Source:HGNC Symbol;Acc:HGNC:9526]	-	-	-	-	GO:0005576//extracellular region;GO:0070021//transforming growth factor beta ligand-receptor complex	GO:0044877//protein-containing complex binding	GO:0002461//tolerance induction dependent upon immune response;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007565//female pregnancy;GO:0010628//positive regulation of gene expression;GO:0036364//transforming growth factor beta1 activation;GO:0045589//regulation of regulatory T cell differentiation;GO:1900016//negative regulation of cytokine production involved in inflammatory response	--
ENSG00000183671	0.808	0.604	0.475	0.289	0.937	0.393	20	18	13	9	21	12	CMKLR2	chemerin chemokine-like receptor 2 [Source:HGNC Symbol;Acc:HGNC:4463]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding;GO:0097003//adipokinetic hormone receptor activity;GO:0097004//adipokinetic hormone binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0042593//glucose homeostasis	--
ENSG00000183682	0.375	0.121	0.128	0.358	0.182	0.165	43.82	14.16	11.07	31.04	18	14	BMP8A	bone morphogenetic protein 8a [Source:HGNC Symbol;Acc:HGNC:21650]	Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Environmental adaptation;Signal transduction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04714//Thermogenesis;ko04390//Hippo signaling pathway;ko04350//TGF-beta signaling pathway	K16622;K16622;K16622;K16622	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070700//BMP receptor binding	GO:0001503//ossification;GO:0002024//diet induced thermogenesis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0051216//cartilage development;GO:0060395//SMAD protein signal transduction;GO:0097009//energy homeostasis	--
ENSG00000183684	27.292	27.764	27.67	31.386	28.714	27.664	621	635	465	529	552	458	ALYREF	Aly/REF export factor [Source:HGNC Symbol;Acc:HGNC:19071]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Transcription;Translation;Translation	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12881;K12881;K12881;K12881;K12881	GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000183688	39.65	40.681	41.769	44.811	40.328	43.515	2978	3071.13	2317	2493	2559	2378	RFLNB	refilin B [Source:HGNC Symbol;Acc:HGNC:28705]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0032432//actin filament bundle	GO:0031005//filamin binding	GO:0001837//epithelial to mesenchymal transition;GO:0030036//actin cytoskeleton organization;GO:0048705//skeletal system morphogenesis;GO:0061181//regulation of chondrocyte development;GO:0061182//negative regulation of chondrocyte development;GO:0061572//actin filament bundle organization;GO:1900158//negative regulation of bone mineralization involved in bone maturation	--
ENSG00000183690	2.679	2.121	2.165	1.139	1.717	1.811	181	144	108	57	98	89	EFHC2	EF-hand domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26233]	-	-	-	-	GO:0005874//microtubule;GO:0005930//axoneme;GO:0036064//ciliary basal body;GO:0072686//mitotic spindle	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0043014//alpha-tubulin binding	GO:0000281//mitotic cytokinesis;GO:0007052//mitotic spindle organization;GO:0010975//regulation of neuron projection development;GO:0060285//cilium-dependent cell motility;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000183691	22.455	20.384	18.802	25.007	29.144	27.917	891	813	551	735	977	806	NOG	noggin [Source:HGNC Symbol;Acc:HGNC:7866]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K04658	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0098793//presynapse	GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0042803//protein homodimerization activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001655//urogenital system development;GO:0001657//ureteric bud development;GO:0001701//in utero embryonic development;GO:0001706//endoderm formation;GO:0001707//mesoderm formation;GO:0001837//epithelial to mesenchymal transition;GO:0001839//neural plate morphogenesis;GO:0001843//neural tube closure;GO:0003149//membranous septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0007224//smoothened signaling pathway;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007492//endoderm development;GO:0008045//motor neuron axon guidance;GO:0008283//cell population proliferation;GO:0008542//visual learning;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0021510//spinal cord development;GO:0021533//cell differentiation in hindbrain;GO:0021915//neural tube development;GO:0021983//pituitary gland development;GO:0030154//cell differentiation;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0035019//somatic stem cell population maintenance;GO:0035640//exploration behavior;GO:0042060//wound healing;GO:0042474//middle ear morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0045596//negative regulation of cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048318//axial mesoderm development;GO:0048570//notochord morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048706//embryonic skeletal system development;GO:0048712//negative regulation of astrocyte differentiation;GO:0048762//mesenchymal cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051216//cartilage development;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060173//limb development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060291//long-term synaptic potentiation;GO:0060302//negative regulation of cytokine activity;GO:0060325//face morphogenesis;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060412//ventricular septum morphogenesis;GO:0060425//lung morphogenesis;GO:0060513//prostatic bud formation;GO:0060676//ureteric bud formation;GO:0060825//fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061037//negative regulation of cartilage development;GO:0061053//somite development;GO:0061312//BMP signaling pathway involved in heart development;GO:0061384//heart trabecula morphogenesis;GO:0061626//pharyngeal arch artery morphogenesis;GO:0071773//cellular response to BMP stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090193//positive regulation of glomerulus development;GO:0099171//presynaptic modulation of chemical synaptic transmission;GO:1904888//cranial skeletal system development;GO:1905006//negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:1990926//short-term synaptic potentiation;GO:2000313//regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000183695	0	0	0	0	0	0	0	0	0	0	0	0	MRGPRX2	MAS related GPR family member X2 [Source:HGNC Symbol;Acc:HGNC:17983]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0042923//neuropeptide binding;GO:1990595//mast cell secretagogue receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0019233//sensory perception of pain;GO:0030431//sleep;GO:0032467//positive regulation of cytokinesis;GO:0043303//mast cell degranulation;GO:0045576//mast cell activation	--
ENSG00000183696	2.688	4.017	4.264	3.3	3.977	2.228	72	91	65	57	73	38	UPP1	uridine phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12576]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00757;K00757;K00757	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004850//uridine phosphorylase activity;GO:0009032//thymidine phosphorylase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042802//identical protein binding;GO:0047847//deoxyuridine phosphorylase activity	GO:0006139//nucleobase-containing compound metabolic process;GO:0006218//uridine catabolic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006248//CMP catabolic process;GO:0006249//dCMP catabolic process;GO:0009116//nucleoside metabolic process;GO:0009164//nucleoside catabolic process;GO:0009166//nucleotide catabolic process;GO:0042149//cellular response to glucose starvation;GO:0044206//UMP salvage;GO:0046050//UMP catabolic process;GO:0046074//dTMP catabolic process;GO:0046079//dUMP catabolic process;GO:0046108//uridine metabolic process	--
ENSG00000183706	0	0	0	0	0	0	0	0	0	0	0	0	OR4N4	olfactory receptor family 4 subfamily N member 4 [Source:HGNC Symbol;Acc:HGNC:15375]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000183709	0	0	0	0	0	0	0	0	0	0	0	0	IFNL2	interferon lambda 2 [Source:HGNC Symbol;Acc:HGNC:18364]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K22669;K22669	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity	GO:0002385//mucosal immune response;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0038196//type III interferon signaling pathway;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus;GO:0098586//cellular response to virus	--
ENSG00000183715	56.721	56.994	50.911	46.15	54.99	53.563	6873	6796	4464	4203	5444.96	4549	OPCML	opioid binding protein/cell adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:8143]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0008038//neuron recognition	--
ENSG00000183718	2.373	1.761	1.81	1.96	2.064	2.333	150	113	87	92	112	108	TRIM52	tripartite motif containing 52 [Source:HGNC Symbol;Acc:HGNC:19024]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0016567//protein ubiquitination;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0051865//protein autoubiquitination"	--
ENSG00000183722	114.207	108.298	111.977	88.789	91.664	110.058	5066	4822	3665	2920	3431	3547	LHFPL6	LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000183723	13.973	13.955	15.023	13.356	14.922	15.287	2349	2315	1774	1673	2067	1881	CMTM4	CKLF like MARVEL transmembrane domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19175]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000183726	37.531	35.116	36.787	38.23	33.922	43.569	1764	1659	1277	1331	1347	1490	TMEM50A	transmembrane protein 50A [Source:HGNC Symbol;Acc:HGNC:30590]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0097386//glial cell projection	GO:0005515//protein binding	GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway	--
ENSG00000183733	0	0	0	0	0	0	0	0	0	0	0	0	FIGLA	folliculogenesis specific bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:24669]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043425//bHLH transcription factor binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0032502//developmental process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048477//oogenesis;GO:0048599//oocyte development	bHLH
ENSG00000183734	0.13	0	0	0	0	0	4	0	0	0	0	0	ASCL2	achaete-scute family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:739]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001890//placenta development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007423//sensory organ development;GO:0010626//negative regulation of Schwann cell proliferation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0035019//somatic stem cell population maintenance;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0060708//spongiotrophoblast differentiation;GO:0060712//spongiotrophoblast layer development	bHLH
ENSG00000183735	9.25	8.28	6.881	6.499	5.812	6.753	563	489	318	301	292	308	TBK1	TANK binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:11584]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Endocrine and metabolic disease;Immune system;Immune system;Transport and catabolism;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko05162//Measles;ko04936//Alcoholic liver disease;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko04137//Mitophagy - animal;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410;K05410	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:1902554//serine/threonine protein kinase complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0051219//phosphoprotein binding;GO:0106310//protein serine kinase activity	GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009615//response to virus;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016239//positive regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032479//regulation of type I interferon production;GO:0032481//positive regulation of type I interferon production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044565//dendritic cell proliferation;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050830//defense response to Gram-positive bacterium;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:1901214//regulation of neuron death;GO:1904417//positive regulation of xenophagy	--
ENSG00000183741	29.924	32.109	36.912	33.815	34.893	37.107	3442	3654	3082	2885	3347	3212	CBX6	chromobox 6 [Source:HGNC Symbol;Acc:HGNC:1556]	-	-	-	-	GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0031519//PcG protein complex	GO:0003727//single-stranded RNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization	--
ENSG00000183742	0.011	0	0	0.075	0.006	0	2	0	0	4	1	0	MACC1	MET transcriptional regulator MACC1 [Source:HGNC Symbol;Acc:HGNC:30215]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051781//positive regulation of cell division	--
ENSG00000183747	0	0	0	0	0	0	0	0	0	0	0	0	ACSM2A	acyl-CoA synthetase medium chain family member 2A [Source:HGNC Symbol;Acc:HGNC:32017]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005524//ATP binding;GO:0015645//fatty acid ligase activity;GO:0016874//ligase activity;GO:0018858//benzoate-CoA ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0102391//decanoate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0036112//medium-chain fatty-acyl-CoA metabolic process;GO:0042593//glucose homeostasis;GO:0070328//triglyceride homeostasis	--
ENSG00000183751	12.639	16.907	14.348	16.808	16.19	15.409	780	998.23	778.94	828.97	904	750	TBL3	transducin beta like 3 [Source:HGNC Symbol;Acc:HGNC:11587]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14555	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030686//90S preribosome;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0034511//U3 snoRNA binding	"GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing"	--
ENSG00000183753	0	0	0	0	0	0	0	0	0	0	0	0	BPY2	basic charge Y-linked 2 [Source:HGNC Symbol;Acc:HGNC:13508]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0032399//HECT domain binding	GO:0007283//spermatogenesis;GO:0007338//single fertilization	--
ENSG00000183760	0	0	0	0	0	0	0	0	0	0	0	0	ACP7	"acid phosphatase 7, tartrate resistant (putative) [Source:HGNC Symbol;Acc:HGNC:33781]"	-	-	-	-	GO:0005576//extracellular region	GO:0003993//acid phosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0016311//dephosphorylation	--
ENSG00000183762	94.507	97.984	100.761	81.305	88.453	94.283	10276	10378	8275	6669.84	8226	7333	KREMEN1	kringle containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:17550]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0016055//Wnt signaling pathway;GO:0030279//negative regulation of ossification;GO:0048681//negative regulation of axon regeneration;GO:0060173//limb development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000183763	1.072	1.361	1.756	0.869	1.015	0.913	45	56	44	22	36	22	TRAIP	TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0090734//site of DNA damage	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0031297//replication fork processing;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032688//negative regulation of interferon-beta production;GO:0106300//protein-DNA covalent cross-linking repair	--
ENSG00000183765	3.704	4.153	3.604	3.225	2.58	2.999	113	136.05	76.03	79.14	71.14	68	CHEK2	checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627]	Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes	Infectious disease: viral;Cell growth and death;Cell growth and death;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04218//Cellular senescence;ko04110//Cell cycle;ko04115//p53 signaling pathway	K06641;K06641;K06641;K06641	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016605//PML body"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000077//DNA damage checkpoint signaling;GO:0000086//G2/M transition of mitotic cell cycle;GO:0001934//positive regulation of protein phosphorylation;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007049//cell cycle;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010332//response to gamma radiation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0042176//regulation of protein catabolic process;GO:0042770//signal transduction in response to DNA damage;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0044257//cellular protein catabolic process;GO:0044773//mitotic DNA damage checkpoint signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0050821//protein stabilization;GO:0051301//cell division;GO:0071466//cellular response to xenobiotic stimulus;GO:0071480//cellular response to gamma radiation;GO:0090307//mitotic spindle assembly;GO:0090399//replicative senescence;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1903416//response to glycoside;GO:1903926//cellular response to bisphenol A;GO:2000002//negative regulation of DNA damage checkpoint;GO:2000210//positive regulation of anoikis"	--
ENSG00000183770	0.017	0	0.022	0	0	0	1	0	1	0	0	0	FOXL2	forkhead box L2 [Source:HGNC Symbol;Acc:HGNC:1092]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090543//Flemming body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0043028//cysteine-type endopeptidase regulator activity involved in apoptotic process;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001541//ovarian follicle development;GO:0001555//oocyte growth;GO:0002074//extraocular skeletal muscle development;GO:0006309//apoptotic DNA fragmentation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007338//single fertilization;GO:0008585//female gonad development;GO:0009653//anatomical structure morphogenesis;GO:0019101//female somatic sex determination;GO:0030154//cell differentiation;GO:0033686//positive regulation of luteinizing hormone secretion;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0048048//embryonic eye morphogenesis;GO:0060014//granulosa cell differentiation;GO:0060065//uterus development"	Fork_head
ENSG00000183773	4.511	5.776	5.633	7.845	9.261	7.536	153	192	172	215	222	155	AIFM3	apoptosis inducing factor mitochondria associated 3 [Source:HGNC Symbol;Acc:HGNC:26398]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	"GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006915//apoptotic process;GO:0097194//execution phase of apoptosis	--
ENSG00000183775	0.308	0.182	0.234	0.212	0.221	0.329	89	53	50	44	54	69	KCTD16	potassium channel tetramerization domain containing 16 [Source:HGNC Symbol;Acc:HGNC:29244]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000183778	1.059	1.277	1.233	0.786	1.053	0.929	286	350	230	159	243	165	B3GALT5	"beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K03877;K03877;K03877	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0009617//response to bacterium	--
ENSG00000183779	3.039	2.994	2.697	4.318	3.476	4.416	209	207	137	220	202	221	ZNF703	zinc finger protein 703 [Source:HGNC Symbol;Acc:HGNC:25883]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0034333//adherens junction assembly;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0060644//mammary gland epithelial cell differentiation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0071392//cellular response to estradiol stimulus"	--
ENSG00000183780	0.681	0.695	0.165	1.084	0.661	0.408	39	40	7	46	32	17	SLC35F3	solute carrier family 35 member F3 [Source:HGNC Symbol;Acc:HGNC:23616]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0015888//thiamine transport	--
ENSG00000183783	0.595	0.665	0.906	0.735	0.924	1.277	32	36	36	29	42	50	KCTD8	potassium channel tetramerization domain containing 8 [Source:HGNC Symbol;Acc:HGNC:22394]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000183785	5.075	3.415	5.919	6.091	4.697	4.342	164.91	128.46	149.61	160.03	141.7	114.2	TUBA8	tubulin alpha 8 [Source:HGNC Symbol;Acc:HGNC:12410]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process	--
ENSG00000183793	3.401	2.454	4.396	3.475	3.546	5.103	69.8	54.94	62.2	46.85	65.53	77.39	NPIPA5	nuclear pore complex interacting protein family member A5 [Source:HGNC Symbol;Acc:HGNC:41980]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000183795	0	0	0	0	0	0	0	0	0	0	0	0	BPY2B	basic charge Y-linked 2B [Source:HGNC Symbol;Acc:HGNC:25449]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0032399//HECT domain binding	GO:0007283//spermatogenesis;GO:0007338//single fertilization	--
ENSG00000183798	5.464	4.787	4.931	6.177	6.028	7.232	429.66	378.32	286.35	359.76	400.43	413.77	EMILIN3	elastin microfibril interfacer 3 [Source:HGNC Symbol;Acc:HGNC:16123]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0042802//identical protein binding	-	--
ENSG00000183801	4.36	2.993	4.388	3.263	4.366	4.629	227	166	160	124	185	174	OLFML1	olfactomedin like 1 [Source:HGNC Symbol;Acc:HGNC:24473]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	GO:0007165//signal transduction	--
ENSG00000183807	0	0	0.063	0	0.055	0	0	0	1	0	1	0	FAM162B	family with sequence similarity 162 member B [Source:HGNC Symbol;Acc:HGNC:21549]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000183808	3.707	3.424	3.108	2.784	3.4	3.593	654.56	607.73	404.11	363.22	507.52	461.05	RBM12B	RNA binding motif protein 12B [Source:HGNC Symbol;Acc:HGNC:32310]	-	-	-	-	GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0043484//regulation of RNA splicing	--
ENSG00000183813	0	0	0	0	0	0	0	0	0	0	0	0	CCR4	C-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:1605]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Cancer: overview;Infectious disease: viral;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04179;K04179;K04179;K04179;K04179	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0001764//neuron migration;GO:0002507//tolerance induction;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0009314//response to radiation;GO:0009617//response to bacterium;GO:0019722//calcium-mediated signaling;GO:0046677//response to antibiotic;GO:0048872//homeostasis of number of cells;GO:0050927//positive regulation of positive chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000183814	2.482	1.634	1.774	1	0.993	1.177	150	103	81	45	49	53	LIN9	lin-9 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:30830]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K21773	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0000003//reproduction;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0051726//regulation of cell cycle;GO:0071897//DNA biosynthetic process"	--
ENSG00000183826	3.704	4.251	3.996	4.037	3.835	5.642	508	555	405	401	430	379	BTBD9	BTB domain containing 9 [Source:HGNC Symbol;Acc:HGNC:21228]	-	-	-	-	-	GO:0005515//protein binding	"GO:0007616//long-term memory;GO:0008344//adult locomotory behavior;GO:0042428//serotonin metabolic process;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0048512//circadian behavior;GO:0050804//modulation of chemical synaptic transmission;GO:0050951//sensory perception of temperature stimulus;GO:0060586//multicellular organismal iron ion homeostasis;GO:1900242//regulation of synaptic vesicle endocytosis"	--
ENSG00000183828	21.678	24.039	27.747	30.257	29.134	24.596	384	428	363	397	436	317	NUDT14	nudix hydrolase 14 [Source:HGNC Symbol;Acc:HGNC:20141]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0008768//UDP-sugar diphosphatase activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity"	GO:0006753//nucleoside phosphate metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019693//ribose phosphate metabolic process	--
ENSG00000183831	0.979	0.806	0.329	0.518	0.558	0.473	54	44.69	13.4	21.17	26	19	ANKRD45	ankyrin repeat domain 45 [Source:HGNC Symbol;Acc:HGNC:24786]	-	-	-	-	GO:0005737//cytoplasm;GO:0030496//midbody;GO:0032154//cleavage furrow	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008283//cell population proliferation	--
ENSG00000183833	2.009	1.817	1.075	1.607	2.207	1.25	103	101	73	53	77	46	CFAP91	cilia and flagella associated protein 91 [Source:HGNC Symbol;Acc:HGNC:24010]	-	-	-	-	GO:0001536//radial spoke stalk;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0007283//spermatogenesis;GO:1904158//axonemal central apparatus assembly	--
ENSG00000183837	1.665	1.862	1.839	2.929	2.371	2.634	119	134	103	157	146	143	PNMA3	PNMA family member 3 [Source:HGNC Symbol;Acc:HGNC:18742]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0043065//positive regulation of apoptotic process	--
ENSG00000183840	0.159	0	0.311	0.522	0.298	0.615	8.49	0	12.26	20.67	13.45	23.89	GPR39	G protein-coupled receptor 39 [Source:HGNC Symbol;Acc:HGNC:4496]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000183844	0.146	0.125	0.099	0.226	0	0	4	3	2	3	0	0	FAM3B	FAM3 metabolism regulating signaling molecule B [Source:HGNC Symbol;Acc:HGNC:1253]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis	--
ENSG00000183850	0.435	0.206	0.281	0.112	0.27	0.114	21	10	10	4	11	4	ZNF730	zinc finger protein 730 [Source:HGNC Symbol;Acc:HGNC:32470]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000183853	23.552	25.533	26.64	27.522	27.22	31.685	3568	3871	2983	3099	3480	3482	KIRREL1	kirre like nephrin family adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:15734]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043198//dendritic shaft;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0017022//myosin binding;GO:0050839//cell adhesion molecule binding	GO:0001933//negative regulation of protein phosphorylation;GO:0003094//glomerular filtration;GO:0030838//positive regulation of actin filament polymerization;GO:0045217//cell-cell junction maintenance;GO:0097017//renal protein absorption;GO:0098609//cell-cell adhesion	--
ENSG00000183856	0.072	0.168	0.173	0.173	0.18	0.238	9	21	15	16	19	19	IQGAP3	IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05767	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding;GO:0070856//myosin VI light chain binding	GO:0000082//G1/S transition of mitotic cell cycle;GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0008361//regulation of cell size;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0032956//regulation of actin cytoskeleton organization;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0043087//regulation of GTPase activity;GO:0043410//positive regulation of MAPK cascade;GO:0070371//ERK1 and ERK2 cascade;GO:0071310//cellular response to organic substance	--
ENSG00000183862	0	0	0	0	0	0	0	0	0	0	0	0	CNGA2	cyclic nucleotide gated channel subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:2149]	Organismal Systems;Environmental Information Processing	Sensory system;Signal transduction	ko04740//Olfactory transduction;ko04024//cAMP signaling pathway	K04949;K04949	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0060170//ciliary membrane	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0005516//calmodulin binding;GO:0030552//cAMP binding;GO:0030553//cGMP binding	GO:0006811//ion transport;GO:0007608//sensory perception of smell;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000183864	17.87	18.281	20.908	23.252	23.106	22.658	1592	1587	1290	1467	1692	1443	TOB2	"transducer of ERBB2, 2 [Source:HGNC Symbol;Acc:HGNC:11980]"	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K14443	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042809//vitamin D receptor binding	"GO:0007292//female gamete generation;GO:0008285//negative regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0045671//negative regulation of osteoclast differentiation;GO:0045778//positive regulation of ossification;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000183873	23.608	22.757	33.22	44.884	45.932	46.56	3876	3727	4014	5485	6348	5558	SCN5A	sodium voltage-gated channel alpha subunit 5 [Source:HGNC Symbol;Acc:HGNC:10593]	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04838	GO:0001518//voltage-gated sodium channel complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0042383//sarcolemma;GO:0048471//perinuclear region of cytoplasm	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0017134//fibroblast growth factor binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030506//ankyrin binding;GO:0031625//ubiquitin protein ligase binding;GO:0044325//transmembrane transporter binding;GO:0050998//nitric-oxide synthase binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0086060//voltage-gated sodium channel activity involved in AV node cell action potential;GO:0086061//voltage-gated sodium channel activity involved in bundle of His cell action potential;GO:0086062//voltage-gated sodium channel activity involved in Purkinje myocyte action potential;GO:0086063//voltage-gated sodium channel activity involved in SA node cell action potential;GO:0097110//scaffold protein binding	GO:0002027//regulation of heart rate;GO:0003161//cardiac conduction system development;GO:0003231//cardiac ventricle development;GO:0003360//brainstem development;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0010765//positive regulation of sodium ion transport;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0019228//neuronal action potential;GO:0021537//telencephalon development;GO:0021549//cerebellum development;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045760//positive regulation of action potential;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051899//membrane depolarization;GO:0055085//transmembrane transport;GO:0060048//cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0071277//cellular response to calcium ion;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086010//membrane depolarization during action potential;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086014//atrial cardiac muscle cell action potential;GO:0086015//SA node cell action potential;GO:0086016//AV node cell action potential;GO:0086043//bundle of His cell action potential;GO:0086045//membrane depolarization during AV node cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086047//membrane depolarization during Purkinje myocyte cell action potential;GO:0086048//membrane depolarization during bundle of His cell action potential;GO:0086067//AV node cell to bundle of His cell communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098655//cation transmembrane transport;GO:0098912//membrane depolarization during atrial cardiac muscle cell action potential;GO:1902305//regulation of sodium ion transmembrane transport	--
ENSG00000183876	8.517	9.591	11.106	15.659	13.746	13.757	484	462	449	661	619	544	ARSI	arylsulfatase family member I [Source:HGNC Symbol;Acc:HGNC:32521]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0005515//protein binding;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000183878	4.415	3.584	3.378	3.723	3.414	3.644	442	361	252	210	262	253	UTY	"ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0044666//MLL3/4 complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032452//histone demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0071558//histone H3-tri/di-methyl-lysine-27 demethylase activity	GO:0006325//chromatin organization;GO:0007507//heart development;GO:0010468//regulation of gene expression;GO:0071557//histone H3-K27 demethylation	--
ENSG00000183888	0	0	0	0	0	0	0	0	0	0	0	0	SRARP	steroid receptor associated and regulated protein [Source:HGNC Symbol;Acc:HGNC:28339]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0030331//estrogen receptor binding	GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway	--
ENSG00000183889	11.075	3.061	9.499	5.034	8.74	8.054	209.68	72.22	96.08	64.9	96.97	68.41	NPIPA7	novel member of the nuclear pore complex interacting protein NPIP gene family	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000183891	1.395	1.355	0.755	1.038	0.877	1.104	27	25	10	15	14	15	TTC32	tetratricopeptide repeat domain 32 [Source:HGNC Symbol;Acc:HGNC:32954]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000183908	0	0	0	0	0	0	0	0	0	0	0	0	LRRC55	leucine rich repeat containing 55 [Source:HGNC Symbol;Acc:HGNC:32324]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0044325//transmembrane transporter binding;GO:0099104//potassium channel activator activity	GO:0006811//ion transport;GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000183914	0.117	0.083	0.036	0.02	0.079	0.014	19	19	8	3	5	3	DNAH2	dynein axonemal heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:2948]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0036156//inner dynein arm;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement;GO:0036159//inner dynein arm assembly;GO:0060285//cilium-dependent cell motility	--
ENSG00000183918	0	0	0	0	0.026	0	0	0	0	0	1	0	SH2D1A	SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07990	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006959//humoral immune response;GO:0006968//cellular defense response;GO:0007267//cell-cell signaling;GO:0045087//innate immune response;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050776//regulation of immune response;GO:0050860//negative regulation of T cell receptor signaling pathway	--
ENSG00000183921	0	0.053	0	0	0	0	0	3	0	0	0	0	SDR42E2	"short chain dehydrogenase/reductase family 42E, member 2 [Source:HGNC Symbol;Acc:HGNC:35414]"	-	-	-	-	-	"GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0006694//steroid biosynthetic process	--
ENSG00000183943	7.901	7.295	6.782	8.394	7.762	7.547	1000	928	634	787	830	695	PRKX	protein kinase X-linked [Source:HGNC Symbol;Acc:HGNC:9441]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005952//cAMP-dependent protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001525//angiogenesis;GO:0001935//endothelial cell proliferation;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030099//myeloid cell differentiation;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0031589//cell-substrate adhesion;GO:0043542//endothelial cell migration;GO:0046777//protein autophosphorylation;GO:0060562//epithelial tube morphogenesis;GO:0060993//kidney morphogenesis;GO:2000696//regulation of epithelial cell differentiation involved in kidney development	--
ENSG00000183955	9.108	6.831	6.761	8.015	8.823	9.114	409	356	234	269	348	309	KMT5A	lysine methyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:29489]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11428;K11428	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0002039//p53 binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042799//histone methyltransferase activity (H4-K20 specific)	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0007049//cell cycle;GO:0007076//mitotic chromosome condensation;GO:0018026//peptidyl-lysine monomethylation;GO:0032259//methylation;GO:0034770//histone H4-K20 methylation;GO:0034968//histone lysine methylation;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051301//cell division;GO:1901796//regulation of signal transduction by p53 class mediator"	--
ENSG00000183960	0.19	0.227	0.129	0.09	0.135	0.117	20	24	10	7	12	9	KCNH8	potassium voltage-gated channel subfamily H member 8 [Source:HGNC Symbol;Acc:HGNC:18864]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000183963	8.628	10.456	9.584	7.07	8.035	9.148	549	620	461	338	459	443	SMTN	smoothelin [Source:HGNC Symbol;Acc:HGNC:11126]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0031941//filamentous actin	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0006939//smooth muscle contraction;GO:0007517//muscle organ development;GO:0030036//actin cytoskeleton organization	--
ENSG00000183971	5.521	6.131	7.91	12.48	14.513	10.499	86	96	91	144	191	119	NPW	neuropeptide W [Source:HGNC Symbol;Acc:HGNC:30509]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23141	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior	--
ENSG00000183977	0.114	0.045	0.031	0	0.054	0.063	5	2	1	0	2	2	PP2D1	protein phosphatase 2C like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28406]	-	-	-	-	-	GO:0004722//protein serine/threonine phosphatase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000183978	42.154	42.226	47.844	50.4	41.922	49.186	682	687	572.52	604	574	579	COA3	cytochrome c oxidase assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:24990]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18175	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000183979	2.52	1.79	0.926	1.646	1.694	0.597	30.06	22.81	8.16	18.87	17.07	7.3	NPB	neuropeptide B [Source:HGNC Symbol;Acc:HGNC:30099]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05267	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior	--
ENSG00000184005	9.645	7.37	4.429	3.326	6.142	9.006	583	439	293	285	297	312	ST6GALNAC3	"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:19343]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03373;K03373;K03373	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0005515//protein binding;GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0047290//(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0006677//glycosylceramide metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0009100//glycoprotein metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0019082//viral protein processing;GO:0097503//sialylation	--
ENSG00000184007	85.717	83.272	79.135	72.369	71.399	79.545	5396	5005	3688	3038	3740	3549	PTP4A2	protein tyrosine phosphatase 4A2 [Source:HGNC Symbol;Acc:HGNC:9635]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000184009	1855.13	1932.529	1898.432	2137.304	2010.431	1631.106	73310	76706	55462	62678	67143	46946	ACTG1	actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases	Neurodegenerative disease;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cell motility;Signal transduction;Transport and catabolism;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes;Infectious disease: viral;Cellular community - eukaryotes;Cancer: specific types;Cardiovascular disease;Signal transduction;Endocrine system;Cell growth and death;Cardiovascular disease;Cardiovascular disease;Immune system;Endocrine system;Immune system;Cardiovascular disease;Infectious disease: bacterial;Cardiovascular disease;Digestive system;Cellular community - eukaryotes;Infectious disease: bacterial	ko05014//Amyotrophic lateral sclerosis;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04714//Thermogenesis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05164//Influenza A;ko04530//Tight junction;ko05225//Hepatocellular carcinoma;ko05414//Dilated cardiomyopathy;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko05416//Viral myocarditis;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04670//Leukocyte transendothelial migration;ko05410//Hypertrophic cardiomyopathy;ko05100//Bacterial invasion of epithelial cells;ko05412//Arrhythmogenic right ventricular cardiomyopathy;ko04971//Gastric acid secretion;ko04520//Adherens junction;ko05110//Vibrio cholerae infection	K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692;K05692	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030016//myofibril;GO:0031941//filamentous actin;GO:0043296//apical junction complex;GO:0044305//calyx of Held;GO:0045177//apical part of cell;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0097433//dense body;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098871//postsynaptic actin cytoskeleton;GO:0099143//presynaptic actin cytoskeleton;GO:0120220//basal body patch	GO:0000166//nucleotide binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0098973//structural constituent of postsynaptic actin cytoskeleton	GO:0001525//angiogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0001895//retina homeostasis;GO:0009612//response to mechanical stimulus;GO:0010628//positive regulation of gene expression;GO:0030335//positive regulation of cell migration;GO:0035633//maintenance of blood-brain barrier;GO:0045214//sarcomere organization;GO:0048488//synaptic vesicle endocytosis;GO:0051492//regulation of stress fiber assembly;GO:0051592//response to calcium ion;GO:0051893//regulation of focal adhesion assembly;GO:0070527//platelet aggregation;GO:0071346//cellular response to interferon-gamma;GO:0090303//positive regulation of wound healing;GO:0098974//postsynaptic actin cytoskeleton organization;GO:0120192//tight junction assembly;GO:0150111//regulation of transepithelial transport;GO:1902396//protein localization to bicellular tight junction	--
ENSG00000184012	0.203	0.015	0	0	0.04	0	6	1	0	0	1	0	TMPRSS2	transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: specific types	ko05171//Coronavirus disease - COVID-19;ko05202//Transcriptional misregulation in cancer;ko05164//Influenza A;ko05215//Prostate cancer	K09633;K09633;K09633;K09633	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0016540//protein autoprocessing;GO:0046598//positive regulation of viral entry into host cell	--
ENSG00000184014	18.987	17.091	19.019	16.085	14.146	18.716	1631	1559	1277	860	1202	1106	DENND5A	DENN domain containing 5A [Source:HGNC Symbol;Acc:HGNC:19344]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0030904//retromer complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0031267//small GTPase binding	"GO:0010977//negative regulation of neuron projection development;GO:0042147//retrograde transport, endosome to Golgi;GO:0050790//regulation of catalytic activity"	--
ENSG00000184022	0	0	0	0	0	0	0	0	0	0	0	0	OR2T10	olfactory receptor family 2 subfamily T member 10 [Source:HGNC Symbol;Acc:HGNC:19573]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184032	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP20-2	keratin associated protein 20-2 [Source:HGNC Symbol;Acc:HGNC:18944]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000184033	0	0	0	0	0	0	0	0	0	0	0	0	CTAG1B	cancer/testis antigen 1B [Source:HGNC Symbol;Acc:HGNC:2491]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0070525//tRNA threonylcarbamoyladenosine metabolic process	--
ENSG00000184047	31.133	30.32	29.233	30.673	27.916	28.14	926.34	897.98	641	681.51	705.23	613	DIABLO	diablo IAP-binding mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:21528]	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04210//Apoptosis;ko04215//Apoptosis - multiple species	K10522;K10522	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035631//CD40 receptor complex	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0043065//positive regulation of apoptotic process;GO:0051402//neuron apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000184056	6.891	7.408	6.882	7.794	7.385	7.752	357.03	385.52	263.68	298.52	323.68	292.6	VPS33B	VPS33B late endosome and lysosome associated [Source:HGNC Symbol;Acc:HGNC:12712]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030897//HOPS complex;GO:0031091//platelet alpha granule;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0033263//CORVET complex;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0099023//vesicle tethering complex	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0006886//intracellular protein transport;GO:0007032//endosome organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0017185//peptidyl-lysine hydroxylation;GO:0032400//melanosome localization;GO:0032418//lysosome localization;GO:0032963//collagen metabolic process;GO:0046907//intracellular transport;GO:0061025//membrane fusion;GO:0070889//platelet alpha granule organization;GO:0090385//phagosome-lysosome fusion	--
ENSG00000184058	0	0	0	0	0	0	0	0	0	0	0	0	TBX1	T-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11592]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001708//cell fate specification;GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0001945//lymph vessel development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003007//heart morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0007389//pattern specification process;GO:0007498//mesoderm development;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007605//sensory perception of sound;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0021644//vagus nerve morphogenesis;GO:0030855//epithelial cell differentiation;GO:0030878//thyroid gland development;GO:0035176//social behavior;GO:0035909//aorta morphogenesis;GO:0042471//ear morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042473//outer ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042693//muscle cell fate commitment;GO:0043410//positive regulation of MAPK cascade;GO:0043587//tongue morphogenesis;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045596//negative regulation of cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0048538//thymus development;GO:0048644//muscle organ morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0048844//artery morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060017//parathyroid gland development;GO:0060023//soft palate development;GO:0060037//pharyngeal system development;GO:0060325//face morphogenesis;GO:0060415//muscle tissue morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0070166//enamel mineralization;GO:0071300//cellular response to retinoic acid;GO:0090103//cochlea morphogenesis;GO:0097152//mesenchymal cell apoptotic process;GO:2000027//regulation of animal organ morphogenesis;GO:2001037//positive regulation of tongue muscle cell differentiation;GO:2001054//negative regulation of mesenchymal cell apoptotic process"	T-box
ENSG00000184060	0.09	0.272	0.189	0.084	0.117	0.08	5	10	6	2	5	3	ADAP2	ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487]	-	-	-	-	GO:0005737//cytoplasm;GO:0005740//mitochondrial envelope;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0030674//protein-macromolecule adaptor activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0046872//metal ion binding;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0007507//heart development;GO:0043547//positive regulation of GTPase activity;GO:0048017//inositol lipid-mediated signaling;GO:0050790//regulation of catalytic activity	--
ENSG00000184076	46.739	45.678	58.657	60.277	49.224	60.71	783	736	704	715	679	741	UQCR10	"ubiquinol-cytochrome c reductase, complex III subunit X [Source:HGNC Symbol;Acc:HGNC:30863]"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419;K00419	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008121//ubiquinol-cytochrome-c reductase activity	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000184083	2.627	2.525	2.901	2.45	2.934	2.262	396	373	306	242	365	275	FAM120C	family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]	-	-	-	-	GO:0005634//nucleus	GO:0003723//RNA binding	-	--
ENSG00000184108	0	0	0	0	0	0	0	0	0	0	0	0	TRIML1	tripartite motif family like 1 [Source:HGNC Symbol;Acc:HGNC:26698]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046596//regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000184110	149.093	157.101	147.314	147.147	141.791	127.882	8959.59	9545.72	6466.09	6573	7238.18	5544.7	EIF3C	eukaryotic translation initiation factor 3 subunit C [Source:HGNC Symbol;Acc:HGNC:3279]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0032991//protein-containing complex;GO:0033290//eukaryotic 48S preinitiation complex	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding;GO:0043022//ribosome binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0045727//positive regulation of translation;GO:1902416//positive regulation of mRNA binding	--
ENSG00000184113	0	0	0	0	0.041	0	0	0	0	0	1	0	CLDN5	claudin 5 [Source:HGNC Symbol;Acc:HGNC:2047]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0033270//paranode region of axon;GO:0043220//Schmidt-Lanterman incisure;GO:0070160//tight junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0003151//outflow tract morphogenesis;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007612//learning;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0016525//negative regulation of angiogenesis;GO:0030336//negative regulation of cell migration;GO:0032092//positive regulation of protein binding;GO:0035633//maintenance of blood-brain barrier;GO:0042552//myelination;GO:0043116//negative regulation of vascular permeability;GO:0045471//response to ethanol;GO:0060021//roof of mouth development;GO:0060325//face morphogenesis;GO:0070830//bicellular tight junction assembly;GO:0120192//tight junction assembly;GO:1903142//positive regulation of establishment of endothelial barrier;GO:1903348//positive regulation of bicellular tight junction assembly;GO:1990963//establishment of blood-retinal barrier	--
ENSG00000184117	53.065	53.683	54.273	56.992	56.838	48.288	2200	2253	1666	1754	2005	1467	NIPSNAP1	nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:7827]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0097060//synaptic membrane	GO:0005515//protein binding;GO:0042165//neurotransmitter binding	GO:0019233//sensory perception of pain	--
ENSG00000184140	0	0	0	0	0	0	0	0	0	0	0	0	OR4F6	olfactory receptor family 4 subfamily F member 6 [Source:HGNC Symbol;Acc:HGNC:15372]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184144	34.15	41.259	23.297	9.935	12.291	11.409	4355	5182	2172	944	1283	1021	CNTN2	contactin 2 [Source:HGNC Symbol;Acc:HGNC:2172]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06760	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0033268//node of Ranvier;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043194//axon initial segment;GO:0043209//myelin sheath;GO:0044224//juxtaparanode region of axon;GO:0045202//synapse;GO:0099025//anchored component of postsynaptic membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0098632//cell-cell adhesion mediator activity	GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration;GO:0002021//response to dietary excess;GO:0002023//reduction of food intake in response to dietary excess;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0007612//learning;GO:0007628//adult walking behavior;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0010954//positive regulation of protein processing;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0022010//central nervous system myelination;GO:0031133//regulation of axon diameter;GO:0031175//neuron projection development;GO:0031623//receptor internalization;GO:0045163//clustering of voltage-gated potassium channels;GO:0045444//fat cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0048710//regulation of astrocyte differentiation;GO:0060168//positive regulation of adenosine receptor signaling pathway;GO:0070593//dendrite self-avoidance;GO:0071205//protein localization to juxtaparanode region of axon;GO:0071206//establishment of protein localization to juxtaparanode region of axon;GO:0097090//presynaptic membrane organization	--
ENSG00000184148	0	0	0	0	0	0	0	0	0	0	0	0	SPRR4	small proline rich protein 4 [Source:HGNC Symbol;Acc:HGNC:23173]	-	-	-	-	GO:0005737//cytoplasm;GO:0005938//cell cortex	-	GO:0031424//keratinization	--
ENSG00000184154	4.447	6.504	3.197	2.958	3.432	2.88	141.53	187.27	73.11	69.84	107.45	62.78	LRRC51	leucine rich repeat containing 51 [Source:HGNC Symbol;Acc:HGNC:55526]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000184155	0	0	0	0	0	0	0	0	0	0	0	0	OR10J5	olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0045765//regulation of angiogenesis;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0051147//regulation of muscle cell differentiation;GO:0055088//lipid homeostasis;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000184156	0.534	0.302	0.285	0.589	0.251	0.14	120	68	30	35	44	13	KCNQ3	potassium voltage-gated channel subfamily Q member 3 [Source:HGNC Symbol;Acc:HGNC:6297]	Organismal Systems	Nervous system	ko04725//Cholinergic synapse	K04928	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033268//node of Ranvier;GO:0043194//axon initial segment;GO:0045202//synapse	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0060081//membrane hyperpolarization;GO:0071805//potassium ion transmembrane transport	--
ENSG00000184160	24.871	21.965	27.276	44.342	41.434	52.913	1068	961	861	1430	1506	1673	ADRA2C	adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:HGNC:283]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04022//cGMP-PKG signaling pathway	K04140;K04140	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004938//alpha2-adrenergic receptor activity;GO:0005515//protein binding;GO:0031694//alpha-2A adrenergic receptor binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051379//epinephrine binding	GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010700//negative regulation of norepinephrine secretion;GO:0019229//regulation of vasoconstriction;GO:0030168//platelet activation;GO:0032148//activation of protein kinase B activity;GO:0032811//negative regulation of epinephrine secretion;GO:0035624//receptor transactivation;GO:0043410//positive regulation of MAPK cascade;GO:0045666//positive regulation of neuron differentiation;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway	--
ENSG00000184162	4.133	3.045	3.161	2.544	2.351	2.26	106.27	69	60.98	49	51.14	44	NR2C2AP	nuclear receptor 2C2 associated protein [Source:HGNC Symbol;Acc:HGNC:30763]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000184163	0.233	0.093	0.567	0.314	0.661	0.959	5	2	9	5	12	15	C1QTNF12	C1q and TNF related 12 [Source:HGNC Symbol;Acc:HGNC:32308]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0010906//regulation of glucose metabolic process;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045721//negative regulation of gluconeogenesis;GO:0046324//regulation of glucose import;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0051897//positive regulation of protein kinase B signaling	--
ENSG00000184164	16.947	17.02	16.986	20	19.149	16.995	498	504	371	440	480	360	CRELD2	cysteine rich with EGF like domains 2 [Source:HGNC Symbol;Acc:HGNC:28150]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus	GO:0003756//protein disulfide isomerase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016853//isomerase activity	-	--
ENSG00000184166	0	0	0	0	0	0	0	0	0	0	0	0	OR1D2	olfactory receptor family 1 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8183]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0042802//identical protein binding	GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007338//single fertilization;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184178	6.219	6.959	6.938	6.376	6.264	6.083	389	440	313	291	313	271	SCFD2	sec1 family domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30676]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0030141//secretory granule	GO:0003674//molecular_function;GO:0019905//syntaxin binding	GO:0006886//intracellular protein transport;GO:0006904//vesicle docking involved in exocytosis;GO:0008150//biological_process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000184182	21.426	19.338	16.792	18.541	17.341	22.761	484	429	323.66	312	352	414.89	UBE2F	ubiquitin conjugating enzyme E2 F (putative) [Source:HGNC Symbol;Acc:HGNC:12480]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10687	GO:0005634//nucleus;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019788//NEDD8 transferase activity;GO:0061654//NEDD8 conjugating enzyme activity	GO:0032446//protein modification by small protein conjugation;GO:0043687//post-translational protein modification;GO:0045116//protein neddylation	--
ENSG00000184185	0.916	0.866	0.986	1.09	1.089	1.725	100	95	57	86	97	137	KCNJ12	potassium inwardly rectifying channel subfamily J member 12 [Source:HGNC Symbol;Acc:HGNC:6258]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04921//Oxytocin signaling pathway;ko04725//Cholinergic synapse	K05005;K05005	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006936//muscle contraction;GO:0008016//regulation of heart contraction;GO:0034765//regulation of ion transmembrane transport;GO:0051289//protein homotetramerization;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000184194	2.856	2.446	3.002	3.624	2.303	3.035	223	182	160	179	161	189	GPR173	G protein-coupled receptor 173 [Source:HGNC Symbol;Acc:HGNC:18186]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004968//gonadotropin-releasing hormone receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:2001223//negative regulation of neuron migration	--
ENSG00000184203	15.934	18.385	18.315	13.609	14.509	16.52	867	824	614	541	598	599	PPP1R2	protein phosphatase 1 regulatory inhibitor subunit 2 [Source:HGNC Symbol;Acc:HGNC:9288]	-	-	-	-	-	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0009966//regulation of signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000184205	4.736	5.182	6.685	3.967	6.028	5.201	258	264	217	154	255	187	TSPYL2	TSPY like 2 [Source:HGNC Symbol;Acc:HGNC:24358]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0000182//rDNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0007049//cell cycle;GO:0008156//negative regulation of DNA replication;GO:0009966//regulation of signal transduction;GO:0030308//negative regulation of cell growth;GO:0045786//negative regulation of cell cycle;GO:0045859//regulation of protein kinase activity	--
ENSG00000184206	0.418	0.696	0.272	0.315	0.43	0.344	39.49	32.8	18.96	22.06	34.29	23.62	GOLGA6L4	golgin A6 family like 4 [Source:HGNC Symbol;Acc:HGNC:27256]	-	-	-	-	-	-	-	--
ENSG00000184207	5.952	6.471	6.953	7.101	6.203	8.452	372	382	337	337	331	350	PGP	phosphoglycolate phosphatase [Source:HGNC Symbol;Acc:HGNC:8909]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K19269;K19269;K19269	GO:0005737//cytoplasm	"GO:0000121//glycerol-1-phosphatase activity;GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008967//phosphoglycolate phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0043136//glycerol-3-phosphatase activity;GO:0046872//metal ion binding;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides"	GO:0005975//carbohydrate metabolic process;GO:0006114//glycerol biosynthetic process;GO:0006650//glycerophospholipid metabolic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0045721//negative regulation of gluconeogenesis	--
ENSG00000184209	7.718	9.966	9.53	11.002	8.016	9.998	188	222	169	188	167	172	SNRNP35	small nuclear ribonucleoprotein U11/U12 subunit 35 [Source:HGNC Symbol;Acc:HGNC:30852]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0017069//snRNA binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000184210	0.084	0	0	0	0	0	3	0	0	0	0	0	DGAT2L6	diacylglycerol O-acyltransferase 2 like 6 [Source:HGNC Symbol;Acc:HGNC:23250]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004144//diacylglycerol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0036155//acylglycerol acyl-chain remodeling	--
ENSG00000184216	29.836	28.16	31.496	36.707	33.444	37.657	2087	1981	1649	1870	1938	1943	IRAK1	interleukin 1 receptor associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:6112]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Nervous system;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04064//NF-kappa B signaling pathway;ko05161//Hepatitis B;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04722//Neurotrophin signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05133//Pertussis	K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730;K04730	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0106310//protein serine kinase activity	GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007254//JNK cascade;GO:0007568//aging;GO:0016310//phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034605//cellular response to heat;GO:0035556//intracellular signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0045087//innate immune response;GO:0046777//protein autophosphorylation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060337//type I interferon signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0071222//cellular response to lipopolysaccharide;GO:0071310//cellular response to organic substance;GO:0071456//cellular response to hypoxia;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell	--
ENSG00000184220	7.149	8.746	8.222	5.571	5.803	5.37	190	240	133	118	128	111	CMSS1	cms1 ribosomal small subunit homolog [Source:HGNC Symbol;Acc:HGNC:28666]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000184221	0	0	0	0	0	0	0	0	0	0	0	0	OLIG1	oligodendrocyte transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:16983]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0014003//oligodendrocyte development;GO:0030182//neuron differentiation;GO:0048663//neuron fate commitment;GO:0048709//oligodendrocyte differentiation"	bHLH
ENSG00000184226	1.259	1.029	0.818	0.898	0.871	1.198	215	158	85	98	123	107	PCDH9	protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0044291//cell-cell contact zone	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000184227	2.159	2.547	1.881	3.113	2.705	3.558	75.51	89.52	48.58	80.65	79.91	89.01	ACOT1	acyl-CoA thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:33128]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04913//Ovarian steroidogenesis;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K01068;K01068;K01068;K01068	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000184232	2.366	2.337	2.478	4.719	3.835	2.197	111	89	77	146	152	75	OAF	out at first homolog [Source:HGNC Symbol;Acc:HGNC:28752]	-	-	-	-	-	-	-	--
ENSG00000184254	333.779	310.935	406.883	306.666	311.673	377.805	23591	22224	21158	16176	18476	19448	ALDH1A3	aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K07249;K07249	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0001758//retinal dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042803//protein homodimerization activity;GO:0070324//thyroid hormone binding;GO:0070403//NAD+ binding"	GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0002138//retinoic acid biosynthetic process;GO:0006629//lipid metabolic process;GO:0007626//locomotory behavior;GO:0021768//nucleus accumbens development;GO:0031076//embryonic camera-type eye development;GO:0042472//inner ear morphogenesis;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043584//nose development;GO:0048048//embryonic eye morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0051289//protein homotetramerization;GO:0060013//righting reflex;GO:0060166//olfactory pit development;GO:0060324//face development;GO:0070384//Harderian gland development	--
ENSG00000184260	0.195	0.583	0.396	0.264	0.231	0.423	2	6	3	2	2	3.15	H2AC20	H2A clustered histone 20 [Source:HGNC Symbol;Acc:HGNC:4738]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000184261	0.044	0.074	0.067	0.075	0.067	0.073	12.49	21	13.86	15.61	16	15	KCNK12	potassium two pore domain channel subfamily K member 12 [Source:HGNC Symbol;Acc:HGNC:6274]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000184270	0	0	0	0	0	0	0	0	0	0	0	0	H2AC21	H2A clustered histone 21 [Source:HGNC Symbol;Acc:HGNC:20508]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000184271	2.252	1.896	2.196	1.687	1.793	2.631	197	208	163	131	170	164	POU6F1	POU class 6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9224]	-	-	-	-	GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0016604//nuclear body	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity	"GO:0006355//regulation of transcription, DNA-templated"	Pou
ENSG00000184276	0	0	0	0	0	0	0	0	0	0	0	0	DEFB108B	defensin beta 108B [Source:HGNC Symbol;Acc:HGNC:29966]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000184277	14.149	13.19	13.233	12.307	12.047	15.702	402	374	282	256	290	327	TM2D3	TM2 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24128]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044214//spanning component of plasma membrane	-	GO:0045747//positive regulation of Notch signaling pathway;GO:0046331//lateral inhibition	--
ENSG00000184281	14.328	13.349	16.098	15.325	16.472	15.157	426	378	356	339	402	321	TSSC4	tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000184292	0.079	0.079	0.072	0.107	0.564	0.073	3	3	2	3	18	2	TACSTD2	tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007601//visual perception;GO:0010633//negative regulation of epithelial cell migration;GO:0050678//regulation of epithelial cell proliferation;GO:0050896//response to stimulus;GO:0051497//negative regulation of stress fiber assembly;GO:0060675//ureteric bud morphogenesis;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900028//negative regulation of ruffle assembly;GO:2000146//negative regulation of cell motility;GO:2000738//positive regulation of stem cell differentiation	--
ENSG00000184302	0.074	0.315	0.201	0	0.154	0.051	4	17	8	0	7	2	SIX6	SIX homeobox 6 [Source:HGNC Symbol;Acc:HGNC:10892]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007601//visual perception;GO:0009887//animal organ morphogenesis"	Homeobox
ENSG00000184304	2.027	1.672	1.434	1.234	1.321	1.192	146	118	78	64	82	58	PRKD1	protein kinase D1 [Source:HGNC Symbol;Acc:HGNC:9407]	Human Diseases;Environmental Information Processing;Organismal Systems	Cancer: overview;Signal transduction;Endocrine system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04015//Rap1 signaling pathway;ko04925//Aldosterone synthesis and secretion	K06070;K06070;K06070	GO:0000421//autophagosome membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004697//protein kinase C activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002376//immune system process;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007399//nervous system development;GO:0010508//positive regulation of autophagy;GO:0010595//positive regulation of endothelial cell migration;GO:0010837//regulation of keratinocyte proliferation;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0030154//cell differentiation;GO:0031647//regulation of protein stability;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034198//cellular response to amino acid starvation;GO:0034599//cellular response to oxidative stress;GO:0035556//intracellular signal transduction;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0042307//positive regulation of protein import into nucleus;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045669//positive regulation of osteoblast differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045806//negative regulation of endocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0050829//defense response to Gram-negative bacterium;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0060548//negative regulation of cell death;GO:0071447//cellular response to hydroperoxide;GO:0089700//protein kinase D signaling;GO:1901727//positive regulation of histone deacetylase activity;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:2001044//regulation of integrin-mediated signaling pathway	--
ENSG00000184305	0.859	0.497	0.485	1.216	0.363	0.831	56	21	11	25	30	24	CCSER1	coiled-coil serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:29349]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000184307	0.843	0.763	0.802	0.747	0.758	0.768	91	88	78	68	72	68	ZDHHC23	zinc finger DHHC-type palmitoyltransferase 23 [Source:HGNC Symbol;Acc:HGNC:28654]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0072659//protein localization to plasma membrane	--
ENSG00000184313	0.538	0.479	0.695	1.195	0.983	0.788	45.98	41.21	44.17	79.96	70.51	46.5	MROH7	maestro heat like repeat family member 7 [Source:HGNC Symbol;Acc:HGNC:24802]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000184330	0	0	0	0	0	0	0	0	0	0	0	0	S100A7A	S100 calcium binding protein A7A [Source:HGNC Symbol;Acc:HGNC:21657]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21126	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000184343	0.068	0.249	0.017	0.038	0	0	4.58	2	1.15	1	0	0	SRPK3	SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000245//spliceosomal complex assembly;GO:0006468//protein phosphorylation;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0050684//regulation of mRNA processing;GO:0060537//muscle tissue development	--
ENSG00000184344	0	0	0	0	0	0	0	0	0	0	0	0	GDF3	growth differentiation factor 3 [Source:HGNC Symbol;Acc:HGNC:4218]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22672	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0019901//protein kinase binding	GO:0001501//skeletal system development;GO:0001654//eye development;GO:0001701//in utero embryonic development;GO:0002021//response to dietary excess;GO:0007165//signal transduction;GO:0007492//endoderm development;GO:0007498//mesoderm development;GO:0010453//regulation of cell fate commitment;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030903//notochord development;GO:0032525//somite rostral/caudal axis specification;GO:0045600//positive regulation of fat cell differentiation;GO:0045605//negative regulation of epidermal cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0048859//formation of anatomical boundary;GO:0060395//SMAD protein signal transduction;GO:0090009//primitive streak formation	--
ENSG00000184345	0	0	0	0	0	0	0	0	0	0	0	0	IQCF2	IQ motif containing F2 [Source:HGNC Symbol;Acc:HGNC:31815]	-	-	-	-	-	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000184347	19.683	21.749	12.155	16.005	21.247	17.258	2465	2809	1152	1526	2257	1601	SLIT3	slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06850	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0048495//Roundabout binding	GO:0003180//aortic valve morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008285//negative regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0010629//negative regulation of gene expression;GO:0016043//cellular component organization;GO:0030154//cell differentiation;GO:0030308//negative regulation of cell growth;GO:0032870//cellular response to hormone stimulus;GO:0035385//Roundabout signaling pathway;GO:0048699//generation of neurons;GO:0048846//axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0051414//response to cortisol;GO:0060412//ventricular septum morphogenesis;GO:0061364//apoptotic process involved in luteolysis;GO:0070100//negative regulation of chemokine-mediated signaling pathway	--
ENSG00000184349	10.535	10.029	9.758	7.138	7.748	7.732	780	731	613	459	549	532	EFNA5	ephrin A5 [Source:HGNC Symbol;Acc:HGNC:3225]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005912//adherens junction;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0071944//cell periphery;GO:0098982//GABA-ergic synapse	GO:0005168//neurotrophin TRKA receptor binding;GO:0005169//neurotrophin TRKB receptor binding;GO:0005170//neurotrophin TRKC receptor binding;GO:0005515//protein binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0045499//chemorepellent activity;GO:0046875//ephrin receptor binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0022407//regulation of cell-cell adhesion;GO:0022604//regulation of cell morphogenesis;GO:0030154//cell differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:0032956//regulation of actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0048668//collateral sprouting;GO:0048672//positive regulation of collateral sprouting;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050919//negative chemotaxis;GO:0051893//regulation of focal adhesion assembly;GO:0051965//positive regulation of synapse assembly;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0099560//synaptic membrane adhesion;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1904322//cellular response to forskolin	--
ENSG00000184350	0.27	0.198	0.254	0.285	0.222	0.323	23	17	16	18	16	20	MRGPRE	MAS related GPR family member E [Source:HGNC Symbol;Acc:HGNC:30694]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000184351	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-1	keratin associated protein 19-1 [Source:HGNC Symbol;Acc:HGNC:18936]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000184357	0	0	0	0	0	0	0	0	0	0	0	0	H1-5	"H1.5 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4719]"	-	-	-	-	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0007517//muscle organ development;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0030307//positive regulation of cell growth;GO:0045910//negative regulation of DNA recombination;GO:0050821//protein stabilization;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0071169//establishment of protein localization to chromatin	--
ENSG00000184361	0.038	0.05	0	0.068	0	0	1	2	0	2	0	0	SPATA32	spermatogenesis associated 32 [Source:HGNC Symbol;Acc:HGNC:26349]	-	-	-	-	GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007283//spermatogenesis	--
ENSG00000184363	0.31	0.068	0.185	0.046	0.192	0	5	4	8	2	9	0	PKP3	plakophilin 3 [Source:HGNC Symbol;Acc:HGNC:9025]	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0030054//cell junction;GO:0030057//desmosome;GO:1990124//messenger ribonucleoprotein complex	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0045294//alpha-catenin binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding;GO:0098641//cadherin binding involved in cell-cell adhesion	GO:0002159//desmosome assembly;GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0010628//positive regulation of gene expression;GO:0072659//protein localization to plasma membrane;GO:0098609//cell-cell adhesion;GO:1902373//negative regulation of mRNA catabolic process	--
ENSG00000184368	0.783	1.024	0.386	0.656	0.34	0.359	66	85	21	26	23	22	MAP7D2	MAP7 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25899]	-	-	-	-	GO:0015630//microtubule cytoskeleton	-	GO:0000226//microtubule cytoskeleton organization	--
ENSG00000184371	9.895	12.109	9.694	16.25	21.862	21.816	503	523	433	676	859	745	CSF1	colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing	Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signal transduction;Signaling molecules and interaction;Signal transduction;Signal transduction;Immune system;Immune disease;Development and regeneration;Signal transduction;Signaling molecules and interaction	ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05453;K05453;K05453;K05453;K05453;K05453;K05453;K05453;K05453;K05453;K05453;K05453	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016604//nuclear body;GO:0048471//perinuclear region of cytoplasm;GO:1990682//CSF1-CSF1R complex	GO:0005125//cytokine activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0001503//ossification;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002158//osteoclast proliferation;GO:0002376//immune system process;GO:0002931//response to ischemia;GO:0003006//developmental process involved in reproduction;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell population proliferation;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010743//regulation of macrophage derived foam cell differentiation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010759//positive regulation of macrophage chemotaxis;GO:0030225//macrophage differentiation;GO:0030278//regulation of ossification;GO:0030316//osteoclast differentiation;GO:0030335//positive regulation of cell migration;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0042117//monocyte activation;GO:0042476//odontogenesis;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0045087//innate immune response;GO:0045651//positive regulation of macrophage differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048873//homeostasis of number of cells within a tissue;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060611//mammary gland fat development;GO:0060763//mammary duct terminal end bud growth;GO:0061518//microglial cell proliferation;GO:1901215//negative regulation of neuron death;GO:1902228//positive regulation of macrophage colony-stimulating factor signaling pathway;GO:1904141//positive regulation of microglial cell migration;GO:1905523//positive regulation of macrophage migration	--
ENSG00000184374	0.015	0	0.021	0	0.036	0	1	0	1	0	2	0	COLEC10	collectin subfamily member 10 [Source:HGNC Symbol;Acc:HGNC:2220]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0009897//external side of plasma membrane;GO:1905370//serine-type endopeptidase complex	GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0042056//chemoattractant activity	"GO:0001867//complement activation, lectin pathway;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0050918//positive chemotaxis;GO:1903028//positive regulation of opsonization;GO:1904888//cranial skeletal system development"	--
ENSG00000184378	1.673	1.119	1.758	1.909	1.332	1.507	58	39	45	49	39	38	ACTRT3	actin related protein T3 [Source:HGNC Symbol;Acc:HGNC:24022]	-	-	-	-	GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	-	-	--
ENSG00000184381	2.524	3.695	4.919	4.184	3.974	5.117	152	233	180	195	212	205	PLA2G6	phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Immune system;Circulatory system;Sensory system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04270//Vascular smooth muscle contraction;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16343;K16343;K16343;K16343;K16343;K16343;K16343;K16343;K16343;K16343	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031143//pseudopodium;GO:0034451//centriolar satellite;GO:0042995//cell projection	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043008//ATP-dependent protein binding;GO:0047499//calcium-independent phospholipase A2 activity;GO:0102545//phosphatidyl phospholipase B activity;GO:0102991//myristoyl-CoA hydrolase activity	"GO:0001934//positive regulation of protein phosphorylation;GO:0006629//lipid metabolic process;GO:0006935//chemotaxis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007613//memory;GO:0014832//urinary bladder smooth muscle contraction;GO:0019731//antibacterial humoral response;GO:0032049//cardiolipin biosynthetic process;GO:0034638//phosphatidylcholine catabolic process;GO:0034976//response to endoplasmic reticulum stress;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0035965//cardiolipin acyl-chain remodeling;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042311//vasodilation;GO:0045921//positive regulation of exocytosis;GO:0046338//phosphatidylethanolamine catabolic process;GO:0046469//platelet activating factor metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0060135//maternal process involved in female pregnancy;GO:0090037//positive regulation of protein kinase C signaling;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0090238//positive regulation of arachidonic acid secretion;GO:1901339//regulation of store-operated calcium channel activity;GO:2000304//positive regulation of ceramide biosynthetic process"	--
ENSG00000184384	5.249	4.536	3.426	3.044	3.934	3.877	680	633	364	305	421	390	MAML2	mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259]	Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Immune system;Signal transduction	ko05165//Human papillomavirus infection;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06061;K06061;K06061	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000184388	0	0.03	0	0	0	0	0	2	0	0	0	0	PABPC1L2B	poly(A) binding protein cytoplasmic 1 like 2B [Source:HGNC Symbol;Acc:HGNC:31852]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000184389	0	0	0	0	0	0	0	0	0	0	0	0	A3GALT2	"alpha 1,3-galactosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:30005]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K20736;K20736	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0032580//Golgi cisterna membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0046872//metal ion binding;GO:0047276//N-acetyllactosaminide 3-alpha-galactosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0030259//lipid glycosylation;GO:0071287//cellular response to manganese ion	--
ENSG00000184394	0	0	0	0	0	0	0	0	0	0	0	0	OR4N5	olfactory receptor family 4 subfamily N member 5 [Source:HGNC Symbol;Acc:HGNC:15358]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184402	10.381	8.671	10.138	10.456	8.976	13.817	841	722	609	663	645	809	SS18L1	SS18L1 subunit of BAF chromatin remodeling complex [Source:HGNC Symbol;Acc:HGNC:15592]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15623	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0071565//nBAF complex"	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0016358//dendrite development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050775//positive regulation of dendrite morphogenesis"	--
ENSG00000184408	3.225	2.773	3.281	2.958	2.976	2.83	390	337	293	265	304	249	KCND2	potassium voltage-gated channel subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:6238]	Organismal Systems	Nervous system	ko04726//Serotonergic synapse	K04892	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031226//intrinsic component of plasma membrane;GO:0032809//neuronal cell body membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0044853//plasma membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1905030//voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0001508//action potential;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007268//chemical synaptic transmission;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0045475//locomotor rhythm;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0060078//regulation of postsynaptic membrane potential;GO:0071456//cellular response to hypoxia;GO:0071805//potassium ion transmembrane transport	--
ENSG00000184428	6.06	6.262	6.197	6.799	7.087	5.792	235	236	164	191	235	161	TOP1MT	DNA topoisomerase I mitochondrial [Source:HGNC Symbol;Acc:HGNC:29787]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid	"GO:0003677//DNA binding;GO:0003916//DNA topoisomerase activity;GO:0003917//DNA topoisomerase type I (single strand cut, ATP-independent) activity;GO:0016853//isomerase activity"	GO:0006260//DNA replication;GO:0006265//DNA topological change	--
ENSG00000184432	71.848	73.615	69	55.137	56.396	58.267	5821.52	5745.32	4062.9	3185.92	3709.79	3445.52	COPB2	COPI coat complex subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:2232]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005198//structural molecule activity;GO:0005515//protein binding	"GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:1901998//toxin transport"	--
ENSG00000184434	0.269	0.027	0.164	0	0.016	0.092	20	2	9	0	1	5	LRRC19	leucine rich repeat containing 19 [Source:HGNC Symbol;Acc:HGNC:23379]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0038008//TRAF-mediated signal transduction;GO:0048874//host-mediated regulation of intestinal microbiota composition;GO:0050727//regulation of inflammatory response;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000184436	12.263	15.515	16.313	13.879	15.946	15.514	295	379	297	251	339	273	THAP7	THAP domain containing 7 [Source:HGNC Symbol;Acc:HGNC:23190]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031493//nucleosomal histone binding;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0070577//lysine-acetylated histone binding;GO:0070742//C2H2 zinc finger domain binding;GO:0106153//phosphorylated histone binding;GO:0140296//general transcription initiation factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0035067//negative regulation of histone acetylation;GO:0045892//negative regulation of transcription, DNA-templated"	THAP
ENSG00000184445	1.472	0.92	0.819	0.648	0.881	0.711	170	120	78	55	92	61	KNTC1	kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:1990423//RZZ complex"	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0000070//mitotic sister chromatid segregation;GO:0007049//cell cycle;GO:0007094//mitotic spindle assembly checkpoint signaling;GO:0007096//regulation of exit from mitosis;GO:0051301//cell division;GO:0065003//protein-containing complex assembly;GO:1903394//protein localization to kinetochore involved in kinetochore assembly	--
ENSG00000184451	0.486	0.56	1.124	0.624	0.621	0.686	13	13	25	11	13	16.06	CCR10	C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474]	Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04672//Intestinal immune network for IgA production;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04185;K04185;K04185;K04185	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000184454	0.036	0.024	0.115	0.082	0.029	0	3	2	7	5	2	0	NCMAP	non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033270//paranode region of axon;GO:0043220//Schmidt-Lanterman incisure	GO:0019911//structural constituent of myelin sheath	GO:0031641//regulation of myelination;GO:0031643//positive regulation of myelination;GO:0032290//peripheral nervous system myelin formation	--
ENSG00000184459	2.775	3.447	4.709	1.458	2.211	1.023	88	92	86	48	80	32	BPIFC	BPI fold containing family C [Source:HGNC Symbol;Acc:HGNC:16503]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001530//lipopolysaccharide binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding	-	--
ENSG00000184465	1.853	1.747	2.603	2.539	1.923	2.468	124	122	123	127	117	122	WDR27	WD repeat domain 27 [Source:HGNC Symbol;Acc:HGNC:21248]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000184470	9.455	8.709	12.143	14.537	12.462	13.086	382	351	356	414	415	384	TXNRD2	thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155]	Human Diseases;Human Diseases;Metabolism	Cancer: overview;Cancer: specific types;Metabolism of other amino acids	ko05200//Pathways in cancer;ko05225//Hepatocellular carcinoma;ko00450//Selenocompound metabolism	K22182;K22182;K22182	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0030424//axon;GO:0030425//dendrite;GO:0043025//neuronal cell body	"GO:0000166//nucleotide binding;GO:0004791//thioredoxin-disulfide reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor;GO:0042803//protein homodimerization activity;GO:0044877//protein-containing complex binding;GO:0050660//flavin adenine dinucleotide binding"	GO:0000305//response to oxygen radical;GO:0009410//response to xenobiotic stimulus;GO:0010269//response to selenium ion;GO:0045454//cell redox homeostasis;GO:0055093//response to hyperoxia;GO:0098869//cellular oxidant detoxification	--
ENSG00000184471	0	0	0	0.038	0.017	0.019	0	0	0	2	1	1	C1QTNF8	C1q and TNF related 8 [Source:HGNC Symbol;Acc:HGNC:31374]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space	GO:0005515//protein binding	GO:2000147//positive regulation of cell motility	--
ENSG00000184478	0	0	0	0	0	0	0	0	0	0	0	0	OR56A3	olfactory receptor family 56 subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:14786]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184481	9.486	6.617	10.33	11.494	8.238	11.021	528	416	488	482	460	404	FOXO4	forkhead box O4 [Source:HGNC Symbol;Acc:HGNC:7139]	Human Diseases;Environmental Information Processing;Environmental Information Processing	Infectious disease: bacterial;Signal transduction;Signal transduction	ko05131//Shigellosis;ko04014//Ras signaling pathway;ko04068//FoxO signaling pathway	K12358;K12358;K12358	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0007517//muscle organ development;GO:0007568//aging;GO:0008285//negative regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0031667//response to nutrient levels;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048863//stem cell differentiation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0070317//negative regulation of G0 to G1 transition;GO:1990785//response to water-immersion restraint stress"	Fork_head
ENSG00000184486	0.01	0	0	0.08	0	0	1	0	0	6	0	0	POU3F2	POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9215]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0008544//epidermis development;GO:0010629//negative regulation of gene expression;GO:0014002//astrocyte development;GO:0014044//Schwann cell development;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0021979//hypothalamus cell differentiation;GO:0021985//neurohypophysis development;GO:0022011//myelination in peripheral nervous system;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0045595//regulation of cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048666//neuron development;GO:0050770//regulation of axonogenesis;GO:0071310//cellular response to organic substance"	Pou
ENSG00000184489	169.535	153.173	180.398	228.423	206.914	255.936	8561	7937	6823	8595	9039	9459	PTP4A3	protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0007219//Notch signaling pathway;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043117//positive regulation of vascular permeability;GO:0043542//endothelial cell migration;GO:1900746//regulation of vascular endothelial growth factor signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1904951//positive regulation of establishment of protein localization;GO:1990830//cellular response to leukemia inhibitory factor"	--
ENSG00000184492	0.019	0.077	0.105	0.105	0.023	0.08	1	4	4	4	1	3	FOXD4L1	forkhead box D4 like 1 [Source:HGNC Symbol;Acc:HGNC:18521]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000184497	0.607	0.489	0.075	0.426	0.427	1.065	16	18	7	8	12	15	TMEM255B	transmembrane protein 255B [Source:HGNC Symbol;Acc:HGNC:28297]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000184500	35.1	31.117	26.273	24.504	26.551	26.769	2446	2188	1359	1272	1572	1367	PROS1	protein S [Source:HGNC Symbol;Acc:HGNC:9456]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03908	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004866//endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010951//negative regulation of endopeptidase activity;GO:0030195//negative regulation of blood coagulation;GO:0042730//fibrinolysis;GO:0050896//response to stimulus	--
ENSG00000184502	0	0	0	0	0	0	0	0	0	0	0	0	GAST	gastrin [Source:HGNC Symbol;Acc:HGNC:4164]	Organismal Systems	Digestive system	ko04971//Gastric acid secretion	K13768	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032094//response to food	--
ENSG00000184507	0	0	0	0.034	0	0	0	0	0	2	0	0	NUTM1	NUT midline carcinoma family member 1 [Source:HGNC Symbol;Acc:HGNC:29919]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000184508	6.497	7.896	5.886	9.768	7.396	7.968	173	217	121	203	176	168	HDDC3	HD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30522]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K21138;K21138	-	"GO:0005515//protein binding;GO:0008893//guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	-	--
ENSG00000184515	1.923	2.284	2.1	2.345	1.91	1.194	31	37	25	28	26	14	BEX5	brain expressed X-linked 5 [Source:HGNC Symbol;Acc:HGNC:27990]	-	-	-	-	GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000184517	4.779	5.373	6.145	2.416	3.171	4.289	295	304	194	122	144	177	ZFP1	ZFP1 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23328]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000184524	0.06	0.508	0.813	0.243	0.284	0.537	2	17	20	6	8	13	CEND1	cell cycle exit and neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:24153]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007628//adult walking behavior;GO:0008150//biological_process;GO:0021549//cerebellum development;GO:0021686//cerebellar granular layer maturation;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021933//radial glia guided migration of cerebellar granule cell;GO:0021941//negative regulation of cerebellar granule cell precursor proliferation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation	--
ENSG00000184530	0.04	0	0.054	0	0.047	0	1	0	1	0	1	0	C6orf58	chromosome 6 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:20960]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000184544	0	0	0	0	0	0.066	0	0	0	0	0	1	DHRS7C	dehydrogenase/reductase 7C [Source:HGNC Symbol;Acc:HGNC:32423]	-	-	-	-	GO:0005576//extracellular region;GO:0014801//longitudinal sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane	GO:0004745//NAD-retinol dehydrogenase activity;GO:0016491//oxidoreductase activity	GO:0006874//cellular calcium ion homeostasis;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0046323//glucose import	--
ENSG00000184545	0.62	0.595	0.778	0.499	0.643	0.745	61	58	54	36	53	51	DUSP8	dual specificity phosphatase 8 [Source:HGNC Symbol;Acc:HGNC:3074]	Environmental Information Processing	Signal transduction	ko04010//MAPK signaling pathway	K04459	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043409//negative regulation of MAPK cascade	--
ENSG00000184557	24.599	26.017	24.998	24.282	25.902	28.283	1395	1483	1047	1020	1241	1167	SOCS3	suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Infectious disease: viral;Infectious disease: viral;Signal transduction;Endocrine and metabolic disease;Infectious disease: viral;Folding, sorting and degradation;Endocrine system;Development and regeneration;Endocrine system;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine and metabolic disease"	"ko05168//Herpes simplex virus 1 infection;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko04120//Ubiquitin mediated proteolysis;ko04910//Insulin signaling pathway;ko04380//Osteoclast differentiation;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04917//Prolactin signaling pathway;ko04920//Adipocytokine signaling pathway;ko04930//Type II diabetes mellitus"	K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696;K04696	GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex	GO:0001784//phosphotyrosine residue binding;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0001932//regulation of protein phosphorylation;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045595//regulation of cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060674//placenta blood vessel development;GO:0060707//trophoblast giant cell differentiation;GO:0060708//spongiotrophoblast differentiation;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000184560	0	0	0	0	0	0	0	0	0	0	0	0	SPEM2	SPEM family member 2 [Source:HGNC Symbol;Acc:HGNC:27315]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000184564	0.017	0.051	0.023	0	0	0	1	4	1	0	0	0	SLITRK6	SLIT and NTRK like family member 6 [Source:HGNC Symbol;Acc:HGNC:23503]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071944//cell periphery	GO:0005515//protein binding	GO:0001964//startle response;GO:0002088//lens development in camera-type eye;GO:0002093//auditory receptor cell morphogenesis;GO:0007409//axonogenesis;GO:0007416//synapse assembly;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0008344//adult locomotory behavior;GO:0021562//vestibulocochlear nerve development;GO:0031223//auditory behavior;GO:0035264//multicellular organism growth;GO:0042472//inner ear morphogenesis;GO:0043010//camera-type eye development;GO:0048812//neuron projection morphogenesis;GO:0050896//response to stimulus;GO:0051965//positive regulation of synapse assembly;GO:0060005//vestibular reflex;GO:0060007//linear vestibuloocular reflex;GO:0060384//innervation;GO:0090102//cochlea development;GO:1905606//regulation of presynapse assembly	--
ENSG00000184571	0	0	0	0	0	0	0	0	0	0	0	0	PIWIL3	piwi like RNA-mediated gene silencing 3 [Source:HGNC Symbol;Acc:HGNC:18443]	Organismal Systems	Development and regeneration	ko04320//Dorso-ventral axis formation	K02156	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043186//P granule	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0034584//piRNA binding	GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0051321//meiotic cell cycle	--
ENSG00000184574	0.054	0	0.049	0.194	0.064	0.074	3	0	2	8	3	3	LPAR5	lysophosphatidic acid receptor 5 [Source:HGNC Symbol;Acc:HGNC:13307]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: bacterial;Cell motility;Signal transduction;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway	K08390;K08390;K08390;K08390;K08390;K08390	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008150//biological_process;GO:0032793//positive regulation of CREB transcription factor activity;GO:0048266//behavioral response to pain	--
ENSG00000184575	22.309	19.966	20.68	17.002	18.445	25.318	2897	2580	2018	1664	2059	2434	XPOT	exportin for tRNA [Source:HGNC Symbol;Acc:HGNC:12826]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K14288	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006409//tRNA export from nucleus;GO:0006886//intracellular protein transport;GO:0006913//nucleocytoplasmic transport;GO:0033036//macromolecule localization;GO:0071528//tRNA re-export from nucleus;GO:0071702//organic substance transport	--
ENSG00000184584	16.895	16.472	20.223	23.176	25.81	20.503	718	694	638	734	924	632	STING1	stimulator of interferon response cGAMP interactor 1 [Source:HGNC Symbol;Acc:HGNC:27962]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko04621//NOD-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12654;K12654;K12654;K12654;K12654;K12654;K12654;K12654	GO:0000421//autophagosome membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005776//autophagosome;GO:0005777//peroxisome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:1902554//serine/threonine protein kinase complex;GO:1990231//STING complex;GO:1990701//integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0035438//cyclic-di-GMP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0061507//2',3'-cyclic GMP-AMP binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	GO:0000045//autophagosome assembly;GO:0002218//activation of innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006914//autophagy;GO:0010468//regulation of gene expression;GO:0016239//positive regulation of macroautophagy;GO:0032092//positive regulation of protein binding;GO:0032481//positive regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0035458//cellular response to interferon-beta;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050727//regulation of inflammatory response;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051259//protein complex oligomerization;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0061709//reticulophagy;GO:0071360//cellular response to exogenous dsRNA;GO:0071407//cellular response to organic cyclic compound	--
ENSG00000184588	7.857	5.761	5.498	4.346	5.026	6.894	613	536	379	297	393	460	PDE4B	phosphodiesterase 4B [Source:HGNC Symbol;Acc:HGNC:8781]	Metabolism;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction"	K13293;K13293;K13293;K13293;K13293	GO:0000930//gamma-tubulin complex;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005891//voltage-gated calcium channel complex;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030018//Z disc;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm;GO:0060076//excitatory synapse;GO:0071944//cell periphery	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0030552//cAMP binding;GO:0043015//gamma-tubulin binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding"	GO:0001780//neutrophil homeostasis;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway;GO:0050900//leukocyte migration;GO:0071222//cellular response to lipopolysaccharide;GO:0071466//cellular response to xenobiotic stimulus;GO:0071872//cellular response to epinephrine stimulus;GO:0086004//regulation of cardiac muscle cell contraction;GO:0140199//negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1901898//negative regulation of relaxation of cardiac muscle	--
ENSG00000184599	0.199	0.198	0.102	0.42	0.286	0.274	6	6	2	9	7	6	TAFA3	TAFA chemokine like family member 3 [Source:HGNC Symbol;Acc:HGNC:21590]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0048018//receptor ligand activity	GO:0007165//signal transduction;GO:0014016//neuroblast differentiation;GO:1902692//regulation of neuroblast proliferation;GO:1903979//negative regulation of microglial cell activation;GO:1903980//positive regulation of microglial cell activation	--
ENSG00000184601	5.653	6.844	7.043	7.457	6.196	7.948	240	263	234	225	218	232	C14orf180	chromosome 14 open reading frame 180 [Source:HGNC Symbol;Acc:HGNC:33795]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000184602	19.704	20.323	23.319	22.613	21.452	24.604	1334	1383	1166	1134	1227	1212	SNN	stannin [Source:HGNC Symbol;Acc:HGNC:11149]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding	GO:0009636//response to toxic substance	--
ENSG00000184611	0.059	0.097	0.034	0	0.03	0	3	5	1	0	1	0	KCNH7	potassium voltage-gated channel subfamily H member 7 [Source:HGNC Symbol;Acc:HGNC:18863]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0044877//protein-containing complex binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0007623//circadian rhythm;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0086011//membrane repolarization during action potential	--
ENSG00000184613	112.457	116.461	120.695	132.827	127.554	135.764	7347	7419	5773	6470	6929	6170	NELL2	neural EGFL like 2 [Source:HGNC Symbol;Acc:HGNC:7751]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0110165//cellular anatomical entity	GO:0005080//protein kinase C binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0009566//fertilization;GO:0070050//neuron cellular homeostasis	--
ENSG00000184616	0	0.034	0	0	0	0	0	2.03	0	0	0	0	SPDYE12	speedy/RINGO cell cycle regulator family member E12 [Source:HGNC Symbol;Acc:HGNC:51508]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000184619	1.642	1.942	1.377	1.412	1.173	1.339	194	201	131	133	108	125	KRBA2	KRAB-A domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26989]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0015074//DNA integration"	--
ENSG00000184634	10.053	11.464	12.498	9.936	11.104	11.975	1341	1475	1156	943	1161	1111	MED12	mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15162	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016592//mediator complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0030374//nuclear receptor coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0001756//somitogenesis;GO:0001843//neural tube closure;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007492//endoderm development;GO:0007507//heart development;GO:0014003//oligodendrocyte development;GO:0014044//Schwann cell development;GO:0016567//protein ubiquitination;GO:0019827//stem cell population maintenance;GO:0021510//spinal cord development;GO:0021915//neural tube development;GO:0036342//post-anal tail morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048702//embryonic neurocranium morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0090245//axis elongation involved in somitogenesis;GO:1990403//embryonic brain development"	--
ENSG00000184635	1.97	0.74	0.924	0.577	0.702	0.719	99	42.05	26	24	34	30	ZNF93	zinc finger protein 93 [Source:HGNC Symbol;Acc:HGNC:13169]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070895//negative regulation of transposon integration"	zf-C2H2
ENSG00000184640	108.437	109.622	118.544	123.989	113.302	98.095	6523	6720	5311	5508	5775	4460	SEPTIN9	septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05131//Shigellosis;ko05100//Bacterial invasion of epithelial cells	K16938;K16938	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005930//axoneme;GO:0005940//septin ring;GO:0015629//actin cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0031105//septin complex;GO:0032153//cell division site;GO:0048471//perinuclear region of cytoplasm;GO:0097730//non-motile cilium	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis;GO:1902857//positive regulation of non-motile cilium assembly	--
ENSG00000184647	0	0	0	0	0	0	0	0	0	0	0	0	PRSS55	serine protease 55 [Source:HGNC Symbol;Acc:HGNC:30824]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007339//binding of sperm to zona pellucida;GO:0030317//flagellated sperm motility	--
ENSG00000184650	0	0	0	0	0	0	0	0	0	0	0	0	ODF4	outer dense fiber of sperm tails 4 [Source:HGNC Symbol;Acc:HGNC:19056]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000184659	0	0	0	0	0	0	0	0	0	0	0	0	FOXD4L4	forkhead box D4 like 4 [Source:HGNC Symbol;Acc:HGNC:23762]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000184661	0.318	0.327	0.446	0.112	0.278	0.152	23	24	24	6	17	8	CDCA2	cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	-	GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0007088//regulation of mitotic nuclear division;GO:0035307//positive regulation of protein dephosphorylation;GO:0051301//cell division;GO:0051983//regulation of chromosome segregation	--
ENSG00000184672	0.619	0.508	0.194	0.553	0.41	0.543	29	28	5	22	18	17	RALYL	RALY RNA binding protein like [Source:HGNC Symbol;Acc:HGNC:27036]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000184675	2.265	2.071	2.516	2.145	2.444	2.514	395	363	324	277	360	319	AMER1	APC membrane recruitment protein 1 [Source:HGNC Symbol;Acc:HGNC:26837]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008013//beta-catenin binding;GO:0008289//lipid binding;GO:1904713//beta-catenin destruction complex binding"	GO:0001822//kidney development;GO:0016055//Wnt signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0060348//bone development;GO:0060612//adipose tissue development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1903364//positive regulation of cellular protein catabolic process	--
ENSG00000184677	5.107	5.501	5.191	4.975	5.03	5.406	918	949	683	613	767	675	ZBTB40	zinc finger and BTB domain containing 40 [Source:HGNC Symbol;Acc:HGNC:29045]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0030282//bone mineralization	ZBTB
ENSG00000184678	2.254	1.984	3.962	3.248	3.13	3.396	104	92	135	111	122	114	H2BC21	H2B clustered histone 21 [Source:HGNC Symbol;Acc:HGNC:4760]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000184697	0	0	0.048	0.095	0.042	0.049	0	0	1	2	1	1	CLDN6	claudin 6 [Source:HGNC Symbol;Acc:HGNC:2048]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction	GO:0001618//virus receptor activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045216//cell-cell junction organization;GO:0046718//viral entry into host cell;GO:0070830//bicellular tight junction assembly	--
ENSG00000184698	0	0	0	0	0	0	0	0	0	0	0	0	OR51M1	olfactory receptor family 51 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:14847]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184702	28.841	30.914	32.45	32.369	27.786	27.432	1108.83	1205.89	925.62	953.67	913.83	812.13	SEPTIN5	septin 5 [Source:HGNC Symbol;Acc:HGNC:9164]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K04557;K04557	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005940//septin ring;GO:0008021//synaptic vesicle;GO:0015630//microtubule cytoskeleton;GO:0031105//septin complex;GO:0032153//cell division site	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0016080//synaptic vesicle targeting;GO:0017157//regulation of exocytosis;GO:0030534//adult behavior;GO:0034613//cellular protein localization;GO:0035176//social behavior;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000184708	11.262	10.789	11.323	10.051	10.697	10.592	836	809	621	550	645	569	EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1 [Source:HGNC Symbol;Acc:HGNC:16687]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003743//translation initiation factor activity;GO:0005049//nuclear export signal receptor activity;GO:0005515//protein binding;GO:0019900//kinase binding	GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006606//protein import into nucleus;GO:0015031//protein transport;GO:0017148//negative regulation of translation;GO:0019827//stem cell population maintenance;GO:0031047//gene silencing by RNA;GO:0033962//P-body assembly;GO:0045665//negative regulation of neuron differentiation;GO:0048255//mRNA stabilization;GO:0051168//nuclear export;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0106289//negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:1905618//positive regulation of miRNA mediated inhibition of translation	--
ENSG00000184709	1.595	2.063	1.404	0.861	0.991	0.603	40	52	26	16	21	11	LRRC26	leucine rich repeat containing 26 [Source:HGNC Symbol;Acc:HGNC:31409]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:0099104//potassium channel activator activity	GO:0006811//ion transport;GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity	--
ENSG00000184716	0.229	0.078	0.18	0.203	0.03	0.189	11.47	3.78	7.23	7.27	1.23	4.35	SERINC4	serine incorporator 4 [Source:HGNC Symbol;Acc:HGNC:32237]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006629//lipid metabolic process;GO:0008654//phospholipid biosynthetic process	--
ENSG00000184719	4.725	5.943	6.161	4.64	6.164	4.68	221	277	164	182	201	178	RNLS	"renalase, FAD dependent amine oxidase [Source:HGNC Symbol;Acc:HGNC:25641]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0051379//epinephrine binding;GO:0070404//NADH binding;GO:0097621//monoamine oxidase activity"	GO:0002931//response to ischemia;GO:0010459//negative regulation of heart rate;GO:0045776//negative regulation of blood pressure;GO:0071869//response to catecholamine;GO:0071871//response to epinephrine;GO:1902074//response to salt	--
ENSG00000184724	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP6-1	keratin associated protein 6-1 [Source:HGNC Symbol;Acc:HGNC:18931]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	GO:0031424//keratinization	--
ENSG00000184730	0.013	0.013	0.052	0	0	0	1	1	3	0	0	0	APOBR	apolipoprotein B receptor [Source:HGNC Symbol;Acc:HGNC:24087]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0042627//chylomicron	GO:0030228//lipoprotein particle receptor activity;GO:0030229//very-low-density lipoprotein particle receptor activity	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process	--
ENSG00000184731	12.749	11.472	12.315	12.833	12.913	17.231	1026	928	732	765	878	1009	FAM110C	family with sequence similarity 110 member C [Source:HGNC Symbol;Acc:HGNC:33340]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005938//cell cortex	GO:0005515//protein binding;GO:0043014//alpha-tubulin binding	GO:0030335//positive regulation of cell migration;GO:0051897//positive regulation of protein kinase B signaling;GO:0060491//regulation of cell projection assembly	--
ENSG00000184735	0	0	0	0	0	0	0	0	0	0	0	0	DDX53	DEAD-box helicase 53 [Source:HGNC Symbol;Acc:HGNC:20083]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000184743	5.552	5.327	5.577	3.898	5.719	5.605	741	714	519	352	569	495	ATL3	atlastin GTPase 3 [Source:HGNC Symbol;Acc:HGNC:24526]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071782//endoplasmic reticulum tubular network;GO:0098826//endoplasmic reticulum tubular network membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0051260//protein homooligomerization;GO:1903373//positive regulation of endoplasmic reticulum tubular network organization	--
ENSG00000184752	27.41	25.276	30.84	28.868	28.243	28.351	319	296	265	249	281	240	NDUFA12	NADH:ubiquinone oxidoreductase subunit A12 [Source:HGNC Symbol;Acc:HGNC:23987]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352;K11352	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005829//cytosol;GO:0016020//membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	GO:0006979//response to oxidative stress;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000184785	0.748	1.035	1.276	1.141	1.077	1.162	23	32	29	26	28	26	SMIM10	small integral membrane protein 10 [Source:HGNC Symbol;Acc:HGNC:41913]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000184786	0.061	0	0	0	0	0	1	0	0	0	0	0	DYNLT2	dynein light chain Tctex-type 2 [Source:HGNC Symbol;Acc:HGNC:11695]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0030286//dynein complex	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000184787	13.308	13.118	15.424	15.542	16.033	16.622	881	911	744	804	946	820	UBE2G2	ubiquitin conjugating enzyme E2 G2 [Source:HGNC Symbol;Acc:HGNC:12483]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K04555;K04555;K04555;K04555	GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0061631//ubiquitin conjugating enzyme activity	"GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0035458//cellular response to interferon-beta;GO:0044257//cellular protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000184788	0.014	0	0.03	0.039	0.017	0	1.01	0	1.02	2.01	1	0	SATL1	spermidine/spermine N1-acetyl transferase like 1 [Source:HGNC Symbol;Acc:HGNC:27992]	-	-	-	-	-	GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	-	--
ENSG00000184792	28.57	29.928	32.379	41.647	36.777	35.877	2082	2102	1624	2093	2146	1809	OSBP2	oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097038//perinuclear endoplasmic reticulum;GO:0097440//apical dendrite	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0032934//sterol binding	GO:0006869//lipid transport;GO:0007286//spermatid development;GO:0015918//sterol transport	--
ENSG00000184811	0	0	0	0	0.08	0	0	0	0	0	5	0	TRARG1	trafficking regulator of GLUT4 (SLC2A4) 1 [Source:HGNC Symbol;Acc:HGNC:29592]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0048471//perinuclear region of cytoplasm	-	GO:0032869//cellular response to insulin stimulus;GO:0044381//glucose import in response to insulin stimulus;GO:0072659//protein localization to plasma membrane;GO:0099500//vesicle fusion to plasma membrane;GO:0099638//endosome to plasma membrane protein transport	--
ENSG00000184814	0	0	0	0	0	0	0	0	0	0	0	0	PRR23B	proline rich 23B [Source:HGNC Symbol;Acc:HGNC:33764]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000184828	0.571	0.748	0.444	0.548	0.564	0.847	58	60	33	41	48	62	ZBTB7C	zinc finger and BTB domain containing 7C [Source:HGNC Symbol;Acc:HGNC:31700]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0045600//positive regulation of fat cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903025//regulation of RNA polymerase II regulatory region sequence-specific DNA binding	ZBTB
ENSG00000184831	11.498	10.554	10.585	10.36	11.478	10.212	217	193	145	152	197	149	APOO	apolipoprotein O [Source:HGNC Symbol;Acc:HGNC:28727]	-	-	-	-	GO:0000139//Golgi membrane;GO:0001401//SAM complex;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0044284//mitochondrial crista junction;GO:0061617//MICOS complex;GO:0140275//MIB complex	GO:0005515//protein binding	GO:0006869//lipid transport;GO:0007007//inner mitochondrial membrane organization;GO:0042407//cristae formation	--
ENSG00000184838	1.576	1.584	1.509	0.974	0.388	0.505	52	53	37	22	12	13	PRR16	proline rich 16 [Source:HGNC Symbol;Acc:HGNC:29654]	-	-	-	-	-	GO:0005515//protein binding	GO:0045727//positive regulation of translation;GO:0045793//positive regulation of cell size	--
ENSG00000184840	54.157	61.265	60.739	57.136	52.896	59.13	2860	3252	2369	2235	2360	2272	TMED9	transmembrane p24 trafficking protein 9 [Source:HGNC Symbol;Acc:HGNC:24878]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019905//syntaxin binding	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0010638//positive regulation of organelle organization;GO:0015031//protein transport;GO:0048205//COPI coating of Golgi vesicle	--
ENSG00000184845	0.526	0.571	0.372	0.662	0.552	0.51	44	48	23	41	39	31	DRD1	dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases	Signaling molecules and interaction;Signal transduction;Neurodegenerative disease;Signal transduction;Substance dependence;Nervous system;Substance dependence;Cellular community - eukaryotes;Substance dependence;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko05032//Morphine addiction;ko04540//Gap junction;ko05031//Amphetamine addiction;ko05030//Cocaine addiction	K04144;K04144;K04144;K04144;K04144;K04144;K04144;K04144;K04144;K04144	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	"GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs;GO:0004930//G protein-coupled receptor activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0005515//protein binding;GO:0035240//dopamine binding"	"GO:0001659//temperature homeostasis;GO:0001661//conditioned taste aversion;GO:0001662//behavioral fear response;GO:0001932//regulation of protein phosphorylation;GO:0001963//synaptic transmission, dopaminergic;GO:0001975//response to amphetamine;GO:0006606//protein import into nucleus;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007212//dopamine receptor signaling pathway;GO:0007416//synapse assembly;GO:0007612//learning;GO:0007613//memory;GO:0007617//mating behavior;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0007628//adult walking behavior;GO:0007631//feeding behavior;GO:0008306//associative learning;GO:0008542//visual learning;GO:0009410//response to xenobiotic stimulus;GO:0010628//positive regulation of gene expression;GO:0014002//astrocyte development;GO:0015872//dopamine transport;GO:0019226//transmission of nerve impulse;GO:0019228//neuronal action potential;GO:0021542//dentate gyrus development;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0030335//positive regulation of cell migration;GO:0030432//peristalsis;GO:0035106//operant conditioning;GO:0042053//regulation of dopamine metabolic process;GO:0042220//response to cocaine;GO:0042311//vasodilation;GO:0042417//dopamine metabolic process;GO:0042711//maternal behavior;GO:0043268//positive regulation of potassium ion transport;GO:0043987//histone H3-S10 phosphorylation;GO:0046323//glucose import;GO:0046959//habituation;GO:0046960//sensitization;GO:0048148//behavioral response to cocaine;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060134//prepulse inhibition;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0071870//cellular response to catecholamine stimulus;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:1903351//cellular response to dopamine;GO:2000300//regulation of synaptic vesicle exocytosis"	--
ENSG00000184857	3.819	3.967	4.808	5.382	4.56	4.006	114	119	106	119	115	87	TMEM186	transmembrane protein 186 [Source:HGNC Symbol;Acc:HGNC:24530]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000184860	0.008	0.021	0.011	0.006	0.01	0.017	2	5	2	1	2	3	SDR42E1	"short chain dehydrogenase/reductase family 42E, member 1 [Source:HGNC Symbol;Acc:HGNC:29834]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0006694//steroid biosynthetic process	--
ENSG00000184863	6.505	6.763	5.357	5.368	7.629	7.168	795	636	455	426	562	468	RBM33	RNA binding motif protein 33 [Source:HGNC Symbol;Acc:HGNC:27223]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000184867	20.957	24.132	24.579	15.969	18.488	17.39	1113	1199	813	582	773	657	ARMCX2	armadillo repeat containing X-linked 2 [Source:HGNC Symbol;Acc:HGNC:16869]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000184887	19.123	17.853	21.015	21.419	19.486	19.154	806.82	755	646	663	692	581	BTBD6	BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19897]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0022008//neurogenesis	--
ENSG00000184895	0.408	0.174	0.237	0.236	0.345	0.24	7	3	3	3	5	3	SRY	sex determining region Y [Source:HGNC Symbol;Acc:HGNC:11311]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007548//sex differentiation;GO:0009653//anatomical structure morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030238//male sex determination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000020//positive regulation of male gonad development"	HMG
ENSG00000184897	41.247	39.834	45.642	48.385	45.057	45.805	1297	1259	1060	1127	1197	1048	H1-10	H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722]	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0031492//nucleosomal DNA binding;GO:0045296//cadherin binding	GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination	--
ENSG00000184898	4.145	3.584	3.236	3.58	3.895	4.173	346	312	207	217	285	263	RBM43	RNA binding motif protein 43 [Source:HGNC Symbol;Acc:HGNC:24790]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000184900	88.605	86.793	88.267	95.727	92.37	96.571	3199	3153	2357	2563	2822	2540	SUMO3	small ubiquitin like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124]	Human Diseases;Genetic Information Processing	Cardiovascular disease;Translation	ko05418//Fluid shear stress and atherosclerosis;ko03013//Nucleocytoplasmic transport	K12160;K12160	GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body	GO:0005515//protein binding;GO:0031386//protein tag;GO:0044389//ubiquitin-like protein ligase binding	GO:0016925//protein sumoylation;GO:0043392//negative regulation of DNA binding;GO:1900180//regulation of protein localization to nucleus	--
ENSG00000184903	17.509	14.438	15.887	15.615	14.525	18.945	367	313	247	257	266	301	IMMP2L	inner mitochondrial membrane peptidase subunit 2 [Source:HGNC Symbol;Acc:HGNC:14598]	Genetic Information Processing	"Folding, sorting and degradation"	ko03060//Protein export	K09648	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042720//mitochondrial inner membrane peptidase complex	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001541//ovarian follicle development;GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006801//superoxide metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0008015//blood circulation;GO:0022904//respiratory electron transport chain;GO:0030728//ovulation;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0061300//cerebellum vasculature development	--
ENSG00000184905	16.722	20.223	16.76	12.9	12.544	9.432	385	468	285	220	244	158	TCEAL2	transcription elongation factor A like 2 [Source:HGNC Symbol;Acc:HGNC:29818]	-	-	-	-	GO:0005634//nucleus	GO:0050699//WW domain binding	-	--
ENSG00000184908	0.43	0.675	0.931	0.428	0.765	0.233	19	32	23	14	29	9	CLCNKB	chloride voltage-gated channel Kb [Source:HGNC Symbol;Acc:HGNC:2027]	Organismal Systems	Excretory system	ko04966//Collecting duct acid secretion	K05018	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0030321//transepithelial chloride transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070293//renal absorption;GO:0070294//renal sodium ion absorption	--
ENSG00000184911	2.999	5.481	3.695	1.871	4.264	4.836	52.96	99.01	40.48	18.72	60.7	59.05	DMRTC1B	DMRT like family C1B [Source:HGNC Symbol;Acc:HGNC:31686]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	-	"GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000184916	1.939	2.37	2.071	2.111	2.365	2.399	232	285	183	187	239	209	JAG2	jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05224//Breast cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K21635;K21635;K21635;K21635;K21635	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001501//skeletal system development;GO:0001701//in utero embryonic development;GO:0003016//respiratory system process;GO:0007154//cell communication;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0009912//auditory receptor cell fate commitment;GO:0016331//morphogenesis of embryonic epithelium;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030217//T cell differentiation;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042492//gamma-delta T cell differentiation;GO:0045061//thymic T cell selection;GO:0045747//positive regulation of Notch signaling pathway;GO:1990134//epithelial cell apoptotic process involved in palatal shelf morphogenesis	--
ENSG00000184922	0.828	0.789	1.061	0.279	0.811	1.107	40	38	35	10	32	33	FMNL1	formin like 1 [Source:HGNC Symbol;Acc:HGNC:1212]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032059//bleb;GO:0042995//cell projection;GO:0045335//phagocytic vesicle;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0032794//GTPase activating protein binding;GO:0051015//actin filament binding	GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0016043//cellular component organization;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0051014//actin filament severing	--
ENSG00000184923	1.006	1.035	1.764	1.452	1.228	1.051	69.59	74.22	90.41	73.53	70.79	52.23	NUTM2A	NUT family member 2A [Source:HGNC Symbol;Acc:HGNC:23438]	-	-	-	-	-	-	-	--
ENSG00000184924	12.175	12.284	13.794	15.302	14.051	12.181	282.84	286.83	236.67	263.32	275.77	205.9	PTRHD1	peptidyl-tRNA hydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33782]	-	-	-	-	-	GO:0004045//aminoacyl-tRNA hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	-	--
ENSG00000184925	0.099	0.197	0.133	0.652	0.234	0.136	1	3	1	6	3	1	LCN12	lipocalin 12 [Source:HGNC Symbol;Acc:HGNC:28733]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001972//retinoic acid binding;GO:0036094//small molecule binding	-	--
ENSG00000184933	0	0	0	0	0	0	0	0	0	0	0	0	OR6A2	olfactory receptor family 6 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:15301]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184937	0.133	0	0.135	0.078	0.226	0.493	3	0	3	2	6	12	WT1	WT1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12796]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09234	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0010385//double-stranded methylated DNA binding;GO:0043565//sequence-specific DNA binding;GO:0044729//hemi-methylated DNA-binding;GO:0046872//metal ion binding;GO:0070742//C2H2 zinc finger domain binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001570//vasculogenesis;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0003156//regulation of animal organ formation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007281//germ cell development;GO:0007356//thorax and anterior abdomen determination;GO:0007507//heart development;GO:0007530//sex determination;GO:0008285//negative regulation of cell population proliferation;GO:0008380//RNA splicing;GO:0008406//gonad development;GO:0008584//male gonad development;GO:0009888//tissue development;GO:0010628//positive regulation of gene expression;GO:0030308//negative regulation of cell growth;GO:0030325//adrenal gland development;GO:0030539//male genitalia development;GO:0030855//epithelial cell differentiation;GO:0032835//glomerulus development;GO:0032836//glomerular basement membrane development;GO:0035802//adrenal cortex formation;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060231//mesenchymal to epithelial transition;GO:0060421//positive regulation of heart growth;GO:0060539//diaphragm development;GO:0060923//cardiac muscle cell fate commitment;GO:0061032//visceral serous pericardium development;GO:0071320//cellular response to cAMP;GO:0071371//cellular response to gonadotropin stimulus;GO:0072075//metanephric mesenchyme development;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072166//posterior mesonephric tubule development;GO:0072207//metanephric epithelium development;GO:0072284//metanephric S-shaped body morphogenesis;GO:0072302//negative regulation of metanephric glomerular mesangial cell proliferation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1905643//positive regulation of DNA methylation;GO:2000020//positive regulation of male gonad development;GO:2000195//negative regulation of female gonad development;GO:2001076//positive regulation of metanephric ureteric bud development"	zf-C2H2
ENSG00000184939	12.876	11.37	14.274	10.271	10.786	11.659	1004	872	653	526	643	639	ZFP90	ZFP90 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23329]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0043392//negative regulation of DNA binding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000184945	0	0	0	0	0	0	0	0	0	0	0	0	AQP12A	aquaporin 12A [Source:HGNC Symbol;Acc:HGNC:19941]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015267//channel activity	GO:0055085//transmembrane transport	--
ENSG00000184949	0.783	0.509	0.595	0.354	0.456	0.391	120	107	78	56	82	53	FAM227A	family with sequence similarity 227 member A [Source:HGNC Symbol;Acc:HGNC:44197]	-	-	-	-	-	-	-	--
ENSG00000184954	0	0	0	0	0	0	0	0	0	0	0	0	OR6C70	olfactory receptor family 6 subfamily C member 70 [Source:HGNC Symbol;Acc:HGNC:31299]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000184956	0	0	0.008	0	0	0	0	0	1	0	0	0	MUC6	"mucin 6, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7517]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000184967	8.006	7.151	7.675	9.546	7.297	7.791	274	246	194	242	211	194	NOC4L	nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030692//Noc4p-Nop14p complex;GO:0031965//nuclear membrane;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000184979	1.972	1.626	1.757	2.032	1.321	2.068	76	63	50	58	43	58	USP18	ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019785//ISG15-specific protease activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0050727//regulation of inflammatory response;GO:0060339//negative regulation of type I interferon-mediated signaling pathway	--
ENSG00000184983	30.775	35.771	37.407	38.228	30.768	38.589	673	797	615	628	578	621	NDUFA6	NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950;K03950	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006979//response to oxidative stress;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000184984	0	0.008	0	0	0	0	0	1	0	0	0	0	CHRM5	cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Signal transduction;Cell motility;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04725//Cholinergic synapse	K04133;K04133;K04133;K04133;K04133;K04133	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004930//G protein-coupled receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0005515//protein binding;GO:0016907//G protein-coupled acetylcholine receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0001696//gastric acid secretion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007197//adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0015872//dopamine transport;GO:0019226//transmission of nerve impulse;GO:0060304//regulation of phosphatidylinositol dephosphorylation;GO:0095500//acetylcholine receptor signaling pathway;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000184985	5.06	5.123	5.293	4.294	5.298	3.868	509	494	347	291	387	304	SORCS2	sortilin related VPS10 domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:16698]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0055038//recycling endosome membrane;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity	GO:0006886//intracellular protein transport;GO:0007218//neuropeptide signaling pathway;GO:0060292//long-term synaptic depression	--
ENSG00000184986	3.582	2.674	3.331	5.718	4.181	4.721	115	86	79	136	113	110	TMEM121	transmembrane protein 121 [Source:HGNC Symbol;Acc:HGNC:20511]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000184988	0.721	0.47	0.395	0.301	0.537	0.304	37	32	14	14	21	15	TMEM106A	transmembrane protein 106A [Source:HGNC Symbol;Acc:HGNC:28288]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002376//immune system process;GO:0008150//biological_process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035780//CD80 biosynthetic process;GO:0035781//CD86 biosynthetic process;GO:0042116//macrophage activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:1904407//positive regulation of nitric oxide metabolic process	--
ENSG00000184990	13.112	18.921	14.937	21.937	19.599	16.49	206	298	173	245	259	187	SIVA1	SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712]	Cellular Processes	Cell growth and death	ko04115//p53 signaling pathway	K22744	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion	"GO:0001618//virus receptor activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005175//CD27 receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0006915//apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0046718//viral entry into host cell;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	--
ENSG00000184992	4.403	4.97	4.55	3.842	5.036	3.898	531	570	376	360	470	362	BRI3BP	BRI3 binding protein [Source:HGNC Symbol;Acc:HGNC:14251]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000184995	0	0	0	0.088	0	0	0	0	0	2	0	0	IFNE	interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04622//RIG-I-like receptor signaling pathway	K05442;K05442;K05442	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0042742//defense response to bacterium;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000184999	0.022	0	0	0	0	0	1	0	0	0	0	0	SLC22A10	solute carrier family 22 member 10 [Source:HGNC Symbol;Acc:HGNC:18057]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0015711//organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000185000	13.175	12.101	16.179	18.456	16.947	17.156	706	742	613	742	755	707	DGAT1	diacylglycerol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2843]	Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Metabolism of cofactors and vitamins;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko00830//Retinol metabolism;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K11155;K11155;K11155;K11155	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0042802//identical protein binding;GO:0050252//retinol O-fatty-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006640//monoacylglycerol biosynthetic process;GO:0006641//triglyceride metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0019915//lipid storage;GO:0034379//very-low-density lipoprotein particle assembly;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0042572//retinol metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0055089//fatty acid homeostasis	--
ENSG00000185002	0	0	0	0	0	0	0	0	0	0	0	0	RFX6	regulatory factor X6 [Source:HGNC Symbol;Acc:HGNC:21478]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K19521	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0003309//type B pancreatic cell differentiation;GO:0003310//pancreatic A cell differentiation;GO:0003311//pancreatic D cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0031018//endocrine pancreas development;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042593//glucose homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050796//regulation of insulin secretion;GO:0090104//pancreatic epsilon cell differentiation"	RFX
ENSG00000185008	10.61	9.018	8.641	5.62	5.367	4.977	1162	1002	710	428	493	473	ROBO2	roundabout guidance receptor 2 [Source:HGNC Symbol;Acc:HGNC:10250]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06754	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030673//axolemma;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0042802//identical protein binding;GO:0098632//cell-cell adhesion mediator activity	GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0003148//outflow tract septum morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003272//endocardial cushion formation;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0016199//axon midline choice point recognition;GO:0021891//olfactory bulb interneuron development;GO:0030154//cell differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:0032870//cellular response to hormone stimulus;GO:0035481//positive regulation of Notch signaling pathway involved in heart induction;GO:0035904//aorta development;GO:0050772//positive regulation of axonogenesis;GO:0050925//negative regulation of negative chemotaxis;GO:0051964//negative regulation of synapse assembly;GO:0060412//ventricular septum morphogenesis;GO:0061364//apoptotic process involved in luteolysis;GO:0098609//cell-cell adhesion	--
ENSG00000185009	20.733	21.013	19.48	15.082	18.919	18.553	1481.94	1421.54	963.43	786.42	1061.13	941.05	AP3M1	adaptor related protein complex 3 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:569]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12398	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030123//AP-3 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0031267//small GTPase binding	"GO:0006622//protein targeting to lysosome;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0008089//anterograde axonal transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0035654//clathrin-coated vesicle cargo loading, AP-3-mediated;GO:0046907//intracellular transport;GO:0048490//anterograde synaptic vesicle transport;GO:0060155//platelet dense granule organization;GO:1903232//melanosome assembly"	--
ENSG00000185010	2.245	1.605	0.97	1.186	1.11	1.325	125	87	53	61	74	39	F8	coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03899	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031093//platelet alpha granule lumen;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	"GO:0006953//acute-phase response;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis"	--
ENSG00000185013	0	0	0	0	0	0	0	0	0	0	0	0	NT5C1B	"5'-nucleotidase, cytosolic IB [Source:HGNC Symbol;Acc:HGNC:17818]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity	GO:0006195//purine nucleotide catabolic process;GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0046085//adenosine metabolic process	--
ENSG00000185015	0.497	0.247	0.437	0.218	0.353	0.444	40	20	26	13	24	26	CA13	carbonic anhydrase 13 [Source:HGNC Symbol;Acc:HGNC:14914]	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00910//Nitrogen metabolism	K01672;K01672	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0043231//intracellular membrane-bounded organelle	GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016829//lyase activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding	GO:0006730//one-carbon metabolic process	--
ENSG00000185019	2.869	3.273	3.082	3.367	2.946	3.263	257	294	203	224	222	212	UBOX5	U-box domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17777]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10600	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0016604//nuclear body	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination	--
ENSG00000185022	2.156	2.771	2.337	1.274	1.803	1.9	106	137	85	46	75	68	MAFF	MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007567//parturition;GO:0035914//skeletal muscle cell differentiation;GO:0045604//regulation of epidermal cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000185024	17.251	14.643	18.037	18.637	17.805	16.098	953.14	958.33	796.89	796.58	914.44	687.71	BRF1	BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551]	-	-	-	-	GO:0000126//transcription factor TFIIIB complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0097550//transcription preinitiation complex	GO:0000995//RNA polymerase III general transcription initiation factor activity;GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0017025//TBP-class protein binding;GO:0046872//metal ion binding	"GO:0006352//DNA-templated transcription, initiation;GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0006413//translational initiation;GO:0009303//rRNA transcription;GO:0009304//tRNA transcription;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0070897//transcription preinitiation complex assembly"	--
ENSG00000185028	0.975	0.821	0.381	0.177	0.311	0.18	52	44	15	7	14	7	LRRC14B	leucine rich repeat containing 14B [Source:HGNC Symbol;Acc:HGNC:37268]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000185033	8.519	9.579	10.735	11.679	9.842	10.598	668	755	613	635	652	595	SEMA4B	semaphorin 4B [Source:HGNC Symbol;Acc:HGNC:10730]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway	--
ENSG00000185038	0.027	0.027	0.037	0.024	0.011	0.012	3	3	3	2	1	1	MROH2A	maestro heat like repeat family member 2A [Source:HGNC Symbol;Acc:HGNC:27936]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000185040	0.227	0.204	0.254	0.507	0.34	0.351	13.29	12	11	22	17	15.08	SPDYE16	speedy/RINGO cell cycle regulator family member E16 [Source:HGNC Symbol;Acc:HGNC:51512]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000185043	30.866	36.88	36.488	34.78	31.616	33.927	726	872	635	605	629	582	CIB1	calcium and integrin binding 1 [Source:HGNC Symbol;Acc:HGNC:16920]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0031982//vesicle;GO:0032433//filopodium tip;GO:0032587//ruffle membrane;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0031267//small GTPase binding;GO:0043495//protein-membrane adaptor activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0001525//angiogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0002931//response to ischemia;GO:0006302//double-strand break repair;GO:0006915//apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0007113//endomitotic cell cycle;GO:0007155//cell adhesion;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010977//negative regulation of neuron projection development;GO:0030154//cell differentiation;GO:0030220//platelet formation;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0031122//cytoplasmic microtubule organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0043086//negative regulation of catalytic activity;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051301//cell division;GO:0051302//regulation of cell division;GO:0051898//negative regulation of protein kinase B signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0090314//positive regulation of protein targeting to membrane;GO:0097191//extrinsic apoptotic signaling pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000256//positive regulation of male germ cell proliferation	--
ENSG00000185046	0.436	0.694	0.483	0.424	0.183	0.254	27.2	18	10	13	7	9	ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24600]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0015030//Cajal body;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0048013//ephrin receptor signaling pathway;GO:1900383//regulation of synaptic plasticity by receptor localization to synapse	--
ENSG00000185049	13.243	12.776	13.628	14.56	13.943	12.752	572	569	464	479	528	412	NELFA	negative elongation factor complex member A [Source:HGNC Symbol;Acc:HGNC:12768]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0032021//NELF complex	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007275//multicellular organism development;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051571//positive regulation of histone H3-K4 methylation	--
ENSG00000185052	0.848	1.48	0.749	0.216	0.451	0.237	69	121	45	13	31	14	SLC24A3	solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044214//spanning component of plasma membrane;GO:0071944//cell periphery	"GO:0005262//calcium channel activity;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030282//bone mineralization;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000185053	0	0.02	0.009	0.018	0	0	0	3	1	2	0	0	SGCZ	sarcoglycan zeta [Source:HGNC Symbol;Acc:HGNC:14075]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016012//sarcoglycan complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0046716//muscle cell cellular homeostasis;GO:0048738//cardiac muscle tissue development;GO:0055001//muscle cell development;GO:0060047//heart contraction;GO:0061024//membrane organization	--
ENSG00000185055	0.157	0.398	0.231	0	0.074	0	3	8.08	3.04	0	2	0	EFCAB10	EF-hand calcium binding domain 10 [Source:HGNC Symbol;Acc:HGNC:34531]	-	-	-	-	-	GO:0005509//calcium ion binding	-	--
ENSG00000185056	0.019	0.019	0.052	0.026	0	0.026	1	1	2	1	0	1	C5orf47	chromosome 5 open reading frame 47 [Source:HGNC Symbol;Acc:HGNC:27026]	-	-	-	-	-	-	-	--
ENSG00000185069	0	0	0	0	0	0	0	0	0	0	0	0	KRT76	keratin 76 [Source:HGNC Symbol;Acc:HGNC:24430]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0008544//epidermis development;GO:0043473//pigmentation;GO:0048733//sebaceous gland development	--
ENSG00000185070	39.752	36.236	40.952	38.6	41.233	44.328	5690	5223	4336	4120	4983	4639	FLRT2	fibronectin leucine rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:3761]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0070062//extracellular exosome	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0045499//chemorepellent activity	GO:0003007//heart morphogenesis;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0008150//biological_process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050919//negative chemotaxis;GO:0051965//positive regulation of synapse assembly;GO:0061343//cell adhesion involved in heart morphogenesis;GO:0071711//basement membrane organization;GO:2001222//regulation of neuron migration	--
ENSG00000185085	8.336	9.62	9.757	10.916	9.971	10.304	568	658.86	491	550.95	574	510.82	INTS5	integrator complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:29352]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0032039//integrator complex	GO:0005515//protein binding	GO:0016180//snRNA processing;GO:0034472//snRNA 3'-end processing	--
ENSG00000185088	7.541	8.204	6.059	9.011	6.575	8.235	153	146.01	87	119	126	113	RPS27L	ribosomal protein S27 like [Source:HGNC Symbol;Acc:HGNC:18476]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02978;K02978	GO:0005634//nucleus;GO:0005840//ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008494//translation activator activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0046872//metal ion binding	"GO:0000028//ribosomal small subunit assembly;GO:0006412//translation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045727//positive regulation of translation"	--
ENSG00000185090	3.202	3.887	4.814	4.509	4.7	3.259	161	192	140	139	204	117	MANEAL	mannosidase endo-alpha like [Source:HGNC Symbol;Acc:HGNC:26452]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004559//alpha-mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	-	--
ENSG00000185100	24.553	27.727	22.837	23.266	24.187	16.145	878	991	593	616	731	420	ADSS1	adenylosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:20093]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K01939;K01939;K01939	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004019//adenylosuccinate synthase activity;GO:0005525//GTP binding;GO:0016874//ligase activity;GO:0042301//phosphate ion binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006164//purine nucleotide biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0046040//IMP metabolic process	--
ENSG00000185101	0.336	0.586	0.888	0.84	0.637	0.624	20	35	39	37	32	27	ANO9	anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005229//intracellular calcium activated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity	GO:0006629//lipid metabolic process;GO:0006821//chloride transport;GO:0006869//lipid transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0061588//calcium activated phospholipid scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling;GO:0061591//calcium activated galactosylceramide scrambling;GO:1902476//chloride transmembrane transport;GO:1902939//negative regulation of intracellular calcium activated chloride channel activity	--
ENSG00000185104	8.633	7.181	8.218	7.133	7.23	6.541	793	715.02	565	444	560	445	FAF1	Fas associated factor 1 [Source:HGNC Symbol;Acc:HGNC:3578]	Cellular Processes	Cell growth and death	ko04217//Necroptosis	K20703	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031265//CD95 death-inducing signaling complex;GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019887//protein kinase regulator activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0051059//NF-kappaB binding	GO:0006915//apoptotic process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0008219//cell death;GO:0010942//positive regulation of cell death;GO:0030155//regulation of cell adhesion;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031334//positive regulation of protein-containing complex assembly;GO:0042176//regulation of protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045740//positive regulation of DNA replication;GO:0050790//regulation of catalytic activity;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1903364//positive regulation of cellular protein catabolic process	--
ENSG00000185105	0	0.059	0.053	0.106	0	0.054	0	3	2	4	0	2	MYADML2	myeloid associated differentiation marker like 2 [Source:HGNC Symbol;Acc:HGNC:34548]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000185112	0.733	1.019	0.497	0.681	0.832	0.777	48	67	24	33	46	37	FAM43A	family with sequence similarity 43 member A [Source:HGNC Symbol;Acc:HGNC:26888]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185115	6.533	6.995	7.279	7.432	6.823	7.772	655	705	539	552	578	567	NSMCE3	"NSE3 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:7677]"	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0030915//Smc5-Smc6 complex"	GO:0005515//protein binding;GO:0046983//protein dimerization activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0031398//positive regulation of protein ubiquitination;GO:0032204//regulation of telomere maintenance;GO:0034644//cellular response to UV;GO:0040008//regulation of growth;GO:0071478//cellular response to radiation;GO:0072711//cellular response to hydroxyurea	--
ENSG00000185122	27.802	25.12	25.803	27.386	29.756	26.418	1162	1092	809	882	1088	823	HSF1	heat shock transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5224]	Human Diseases	Infectious disease: bacterial	ko05134//Legionellosis	K09414	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000785//chromatin;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016605//PML body;GO:0048471//perinuclear region of cytoplasm;GO:0097165//nuclear stress granule;GO:0097431//mitotic spindle pole;GO:0101031//chaperone complex;GO:1990904//ribonucleoprotein complex"	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031072//heat shock protein binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0043621//protein self-association;GO:0046982//protein heterodimerization activity;GO:0051879//Hsp90 protein binding;GO:0061770//translation elongation factor binding;GO:0097677//STAT family protein binding;GO:0098847//sequence-specific single stranded DNA binding;GO:0140296//general transcription initiation factor binding;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006397//mRNA processing;GO:0006952//defense response;GO:0006974//cellular response to DNA damage stimulus;GO:0007584//response to nutrient;GO:0008284//positive regulation of cell population proliferation;GO:0009299//mRNA transcription;GO:0009408//response to heat;GO:0010243//response to organonitrogen compound;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032355//response to estradiol;GO:0033574//response to testosterone;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0034622//cellular protein-containing complex assembly;GO:0035865//cellular response to potassium ion;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043200//response to amino acid;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045651//positive regulation of macrophage differentiation;GO:0045931//positive regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051028//mRNA transport;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0061408//positive regulation of transcription from RNA polymerase II promoter in response to heat stress;GO:0070301//cellular response to hydrogen peroxide;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071392//cellular response to estradiol stimulus;GO:0071407//cellular response to organic cyclic compound;GO:0071466//cellular response to xenobiotic stimulus;GO:0071478//cellular response to radiation;GO:0071480//cellular response to gamma radiation;GO:0072738//cellular response to diamide;GO:0090084//negative regulation of inclusion body assembly;GO:0090261//positive regulation of inclusion body assembly;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1900034//regulation of cellular response to heat;GO:1900365//positive regulation of mRNA polyadenylation;GO:1901215//negative regulation of neuron death;GO:1901652//response to peptide;GO:1902512//positive regulation of apoptotic DNA fragmentation;GO:1903936//cellular response to sodium arsenite;GO:1904385//cellular response to angiotensin;GO:1904528//positive regulation of microtubule binding;GO:1904843//cellular response to nitroglycerin;GO:1904845//cellular response to L-glutamine;GO:1990910//response to hypobaric hypoxia;GO:1990911//response to psychosocial stress;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining"	HSF
ENSG00000185127	17.539	15.536	15.297	16.863	18.308	16.248	970.26	863.85	625	691	855.67	654	C6orf120	chromosome 6 open reading frame 120 [Source:HGNC Symbol;Acc:HGNC:21247]	-	-	-	-	GO:0005576//extracellular region;GO:0035578//azurophil granule lumen	-	GO:0006915//apoptotic process	--
ENSG00000185129	5.587	3.844	4.311	4.068	5.323	4.131	1122	785	575	526	685	541	PURA	purine rich element binding protein A [Source:HGNC Symbol;Acc:HGNC:9701]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0032839//dendrite cytoplasm;GO:0043025//neuronal cell body;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity"	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003697//single-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0032422//purine-rich negative regulatory element binding;GO:0046332//SMAD binding;GO:0140297//DNA-binding transcription factor binding;GO:0140416//transcription regulator inhibitor activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0042127//regulation of cell population proliferation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046651//lymphocyte proliferation;GO:0050673//epithelial cell proliferation;GO:0098963//dendritic transport of messenger ribonucleoprotein complex"	Others
ENSG00000185130	0	0.106	0	0	0	0	0	1	0	0	0	0	H2BC13	H2B clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4748]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000185133	1.373	0.791	1.525	1.419	0.665	1.466	84	48	61	73	39	70	INPP5J	inositol polyphosphate-5-phosphatase J [Source:HGNC Symbol;Acc:HGNC:8956]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00562//Inositol phosphate metabolism	K24222;K24222	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0019898//extrinsic component of membrane;GO:0030426//growth cone;GO:0043198//dendritic shaft;GO:0110165//cellular anatomical entity	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017124//SH3 domain binding;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"	GO:0006661//phosphatidylinositol biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0019637//organophosphate metabolic process;GO:0031115//negative regulation of microtubule polymerization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000185149	0.096	0.225	0.056	0.093	0.081	0.17	7	17	3	5	5	9	NPY2R	neuropeptide Y receptor Y2 [Source:HGNC Symbol;Acc:HGNC:7957]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04205	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097730//non-motile cilium	GO:0001601//peptide YY receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0003151//outflow tract morphogenesis;GO:0003214//cardiac left ventricle morphogenesis;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007626//locomotory behavior	--
ENSG00000185155	0.025	0.024	0.066	0.095	0.029	0.067	1	1	2	2	1	2	MIXL1	Mix paired-like homeobox [Source:HGNC Symbol;Acc:HGNC:13363]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001706//endoderm formation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0007507//heart development;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0035987//endodermal cell differentiation;GO:0042074//cell migration involved in gastrulation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048565//digestive tract development;GO:1901533//negative regulation of hematopoietic progenitor cell differentiation;GO:2000382//positive regulation of mesoderm development"	Homeobox
ENSG00000185156	0	0	0	0.058	0	0.059	0	0	0	2	0	2	MFSD6L	major facilitator superfamily domain containing 6 like [Source:HGNC Symbol;Acc:HGNC:26656]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000185158	5.696	4.674	6.964	4.208	4.16	4.952	136	124	126	79	108	90	LRRC37B	leucine rich repeat containing 37B [Source:HGNC Symbol;Acc:HGNC:29070]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000185163	2.328	2.479	2.166	2.367	2.876	2.212	227	243	156	171	237	157	DDX51	DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis	--
ENSG00000185164	77.039	77.289	75.846	70.064	72.982	79.092	5077.81	4941.82	3710.59	3409.99	4030.34	3686.28	NOMO2	NODAL modulator 2 [Source:HGNC Symbol;Acc:HGNC:22652]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0043022//ribosome binding	-	--
ENSG00000185176	0.016	0	0	0	0	0	1	0	0	0	0	0	AQP12B	aquaporin 12B [Source:HGNC Symbol;Acc:HGNC:6096]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015267//channel activity	GO:0055085//transmembrane transport	--
ENSG00000185177	0	0	0	0	0	0	0	0	0	0	0	0	ZNF479	zinc finger protein 479 [Source:HGNC Symbol;Acc:HGNC:23258]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000185187	4.877	4.664	5.55	7.649	4.723	5.647	86	83	84	101	80	85	SIGIRR	single Ig and TIR domain containing [Source:HGNC Symbol;Acc:HGNC:30575]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003953//NAD+ nucleosidase activity;GO:0005515//protein binding	GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0006953//acute-phase response;GO:0007165//signal transduction;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032682//negative regulation of chemokine production;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0071345//cellular response to cytokine stimulus	--
ENSG00000185189	40.686	39.364	37.213	33.709	38.199	37.157	3031	2976	2074	1899	2393	2002	NRBP2	nuclear receptor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19339]	-	-	-	-	GO:0005737//cytoplasm;GO:0012505//endomembrane system	GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007399//nervous system development;GO:0016242//negative regulation of macroautophagy;GO:0030182//neuron differentiation;GO:0035556//intracellular signal transduction;GO:0043524//negative regulation of neuron apoptotic process	--
ENSG00000185198	0	0	0	0	0	0	0	0	0	0	0	0	PRSS57	serine protease 57 [Source:HGNC Symbol;Acc:HGNC:31397]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen	GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000185201	72.822	77.956	91.905	101.562	100.72	94.676	1289.34	1332.49	1130.43	1281	1476.88	1179.23	IFITM2	interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex	-	GO:0002376//immune system process;GO:0006955//immune response;GO:0009615//response to virus;GO:0034341//response to interferon-gamma;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0035458//cellular response to interferon-beta;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway	--
ENSG00000185215	1.402	1.514	0.675	1.157	1.866	1.081	82	103	36	45	55	68	TNFAIP2	TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895]	-	-	-	-	GO:0000145//exocyst;GO:0005615//extracellular space	GO:0000149//SNARE binding;GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006887//exocytosis;GO:0030154//cell differentiation;GO:0051601//exocyst localization	--
ENSG00000185219	2.969	2.75	3.092	2.142	2.618	2.407	684	618.37	513	357	496	402	ZNF445	zinc finger protein 445 [Source:HGNC Symbol;Acc:HGNC:21018]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0010385//double-stranded methylated DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010216//maintenance of DNA methylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000653//regulation of genetic imprinting"	zf-C2H2
ENSG00000185220	2.442	2.724	2.748	2.998	3.246	2.593	141	157	116	128	157	108	PGBD2	piggyBac transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:19399]	-	-	-	-	-	GO:0043565//sequence-specific DNA binding	-	--
ENSG00000185222	48.411	50.604	45.539	38.235	34.141	40.724	957	997	663	554	567	579	TCEAL9	transcription elongation factor A like 9 [Source:HGNC Symbol;Acc:HGNC:30084]	-	-	-	-	GO:0005634//nucleus	GO:0050699//WW domain binding	-	--
ENSG00000185231	0	0	0	0	0	0	0	0	0	0	0	0	MC2R	melanocortin 2 receptor [Source:HGNC Symbol;Acc:HGNC:6930]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion	K04200;K04200;K04200;K04200;K04200	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004977//melanocortin receptor activity;GO:0004978//corticotropin receptor activity;GO:0005515//protein binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0019222//regulation of metabolic process"	--
ENSG00000185236	68.097	76.079	80.618	92.133	81.845	71.935	2233	2506	1949	2227	2257	1711	RAB11B	"RAB11B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9761]"	Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Transport and catabolism;Infectious disease: viral;Signal transduction;Excretory system	ko04144//Endocytosis;ko05164//Influenza A;ko04152//AMPK signaling pathway;ko04962//Vasopressin-regulated water reabsorption	K07905;K07905;K07905;K07905	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0030670//phagocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0045335//phagocytic vesicle;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0031489//myosin V binding;GO:0045296//cadherin binding	GO:0001881//receptor recycling;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0032402//melanosome transport;GO:0032456//endocytic recycling;GO:0033572//transferrin transport;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0044070//regulation of anion transport;GO:0045054//constitutive secretory pathway;GO:0045055//regulated exocytosis;GO:0071468//cellular response to acidic pH;GO:0090150//establishment of protein localization to membrane;GO:0150093//amyloid-beta clearance by transcytosis;GO:2000008//regulation of protein localization to cell surface;GO:2001135//regulation of endocytic recycling	--
ENSG00000185238	3.342	3.241	4.144	4.322	4.039	5.664	169	138	162	139	170	191	PRMT3	protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0043022//ribosome binding;GO:0046872//metal ion binding;GO:0072341//modified amino acid binding	"GO:0006479//protein methylation;GO:0018216//peptidyl-arginine methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0031397//negative regulation of protein ubiquitination;GO:0032259//methylation;GO:0060997//dendritic spine morphogenesis;GO:1900053//negative regulation of retinoic acid biosynthetic process"	--
ENSG00000185245	0.192	0.248	0.493	0.518	0.545	0.264	10	13	19	20	24	10	GP1BA	glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439]	Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing	Immune system;Immune system;Immune system;Signaling molecules and interaction	ko04613//Neutrophil extracellular trap formation;ko04640//Hematopoietic cell lineage;ko04611//Platelet activation;ko04512//ECM-receptor interaction	K06261;K06261;K06261;K06261	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0031362//anchored component of external side of plasma membrane;GO:0070062//extracellular exosome;GO:1990779//glycoprotein Ib-IX-V complex	GO:0005515//protein binding;GO:0015057//thrombin-activated receptor activity	"GO:0000902//cell morphogenesis;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis;GO:0010572//positive regulation of platelet activation;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0035855//megakaryocyte development;GO:0042730//fibrinolysis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070493//thrombin-activated receptor signaling pathway;GO:0070527//platelet aggregation"	--
ENSG00000185246	5.53	3.49	4.461	3.023	3.675	4.409	382.89	243.5	188.09	152.67	216.04	219.87	PRPF39	pre-mRNA processing factor 39 [Source:HGNC Symbol;Acc:HGNC:20314]	-	-	-	-	GO:0000243//commitment complex;GO:0005634//nucleus;GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome	GO:0005515//protein binding	GO:0000395//mRNA 5'-splice site recognition;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000185247	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA11	MAGE family member A11 [Source:HGNC Symbol;Acc:HGNC:6798]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000185250	2.912	1.5	1.669	1.329	0.794	0.979	70.04	56.49	44.93	24.22	30.89	24.6	PPIL6	peptidylprolyl isomerase like 6 [Source:HGNC Symbol;Acc:HGNC:21557]	-	-	-	-	GO:0005737//cytoplasm	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000185252	6.376	6.233	6.311	6.482	6.64	6.807	448	467	341	344	411	366	ZNF74	zinc finger protein 74 [Source:HGNC Symbol;Acc:HGNC:13144]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development"	zf-C2H2
ENSG00000185261	1.445	1.033	0.935	0.848	0.445	0.891	86	72.03	39	31	26	39	KIAA0825	KIAA0825 [Source:HGNC Symbol;Acc:HGNC:28532]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185262	6.968	5.976	6.739	6.257	5.988	6.507	209	170	147	139	148	142	UBALD2	UBA like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28438]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185264	0	0	0	0	0	0	0	0	0	0	0	0	TEX33	testis expressed 33 [Source:HGNC Symbol;Acc:HGNC:28568]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185267	1.152	0.828	1.033	0.421	0.78	0.238	34	24	22	9	19	5	CDNF	cerebral dopamine neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:24913]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0071542//dopaminergic neuron differentiation	--
ENSG00000185269	0.737	0.838	0.675	0.498	0.627	0.619	34	28	23	17	14	19	NOTUM	"notum, palmitoleoyl-protein carboxylesterase [Source:HGNC Symbol;Acc:HGNC:27106]"	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K19882	GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen	GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:1990699//palmitoleyl hydrolase activity	GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030500//regulation of bone mineralization;GO:0060348//bone development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1990697//protein depalmitoleylation	--
ENSG00000185271	0.018	0	0	0	0	0	2	0	0	0	0	0	KLHL33	kelch like family member 33 [Source:HGNC Symbol;Acc:HGNC:31952]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185272	1.702	1.349	1.202	0.699	0.934	0.78	69	55	36	21	32	23	RBM11	RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0042803//protein homodimerization activity	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0030154//cell differentiation;GO:0034599//cellular response to oxidative stress"	--
ENSG00000185274	2.557	3.339	1.77	1.584	1.938	1.207	187	255	106	86	114	63	GALNT17	polypeptide N-acetylgalactosaminyltransferase 17 [Source:HGNC Symbol;Acc:HGNC:16347]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation	--
ENSG00000185278	1.141	0.833	1.239	0.74	0.996	1.264	424	333	289	218	293	242	ZBTB37	zinc finger and BTB domain containing 37 [Source:HGNC Symbol;Acc:HGNC:28365]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000185290	0	0	0	0	0	0	0	0	0	0	0	0	NUPR2	"nuclear protein 2, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:44164]"	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0045786//negative regulation of cell cycle;GO:0051726//regulation of cell cycle	--
ENSG00000185291	0	0.031	0.212	0.044	0.222	0	0	1	5	1	6	0	IL3RA	interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Cellular Processes	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction;Cell growth and death	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway;ko04210//Apoptosis	K04737;K04737;K04737;K04737;K04737;K04737	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004912//interleukin-3 receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0019221//cytokine-mediated signaling pathway;GO:0036016//cellular response to interleukin-3;GO:0038156//interleukin-3-mediated signaling pathway	--
ENSG00000185294	0	0	0	0	0	0	0	0	0	0	0	0	SPPL2C	signal peptide peptidase like 2C [Source:HGNC Symbol;Acc:HGNC:28902]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	"GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0042803//protein homodimerization activity"	GO:0006508//proteolysis;GO:0033619//membrane protein proteolysis	--
ENSG00000185298	7.781	7.013	7.843	7.643	6.331	6.523	300	303	205	246	232	194	CCDC137	coiled-coil domain containing 137 [Source:HGNC Symbol;Acc:HGNC:33451]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000185303	0	0	0	0	0	0	0	0	0	0	0	0	SFTPA2	surfactant protein A2 [Source:HGNC Symbol;Acc:HGNC:10799]	Cellular Processes;Human Diseases	Transport and catabolism;Infectious disease: bacterial	ko04145//Phagosome;ko05133//Pertussis	K10067;K10067	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005771//multivesicular body;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0042599//lamellar body;GO:0045334//clathrin-coated endocytic vesicle	GO:0005515//protein binding;GO:0030246//carbohydrate binding	GO:0007585//respiratory gaseous exchange by respiratory system	--
ENSG00000185304	0.067	0.055	0.11	0	0.014	0.092	9.46	7.83	11.41	0	1.7	9.35	RGPD2	RANBP2 like and GRIP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:32415]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000185305	9.813	8.908	6.767	7.099	5.144	6.929	545	448	345	295	300	348	ARL15	ADP ribosylation factor like GTPase 15 [Source:HGNC Symbol;Acc:HGNC:25945]	-	-	-	-	GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0008150//biological_process	--
ENSG00000185306	0.024	0	0	0	0.014	0	2	0	0	0	1	0	C12orf56	chromosome 12 open reading frame 56 [Source:HGNC Symbol;Acc:HGNC:26967]	-	-	-	-	-	-	-	--
ENSG00000185313	0	0.016	0	0	0	0	0	2	0	0	0	0	SCN10A	sodium voltage-gated channel alpha subunit 10 [Source:HGNC Symbol;Acc:HGNC:10582]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0071439//clathrin complex;GO:0098978//glutamatergic synapse;GO:0099056//integral component of presynaptic membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0044325//transmembrane transporter binding	GO:0002027//regulation of heart rate;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007600//sensory perception;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042475//odontogenesis of dentin-containing tooth;GO:0055085//transmembrane transport;GO:0055117//regulation of cardiac muscle contraction;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0086010//membrane depolarization during action potential;GO:0086016//AV node cell action potential;GO:0086043//bundle of His cell action potential;GO:0098655//cation transmembrane transport	--
ENSG00000185324	11.513	12.727	13.436	12.834	12.357	11.863	360	405	283	291	306	254	CDK10	cyclin dependent kinase 10 [Source:HGNC Symbol;Acc:HGNC:1770]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0097472//cyclin-dependent protein kinase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007089//traversing start control point of mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008285//negative regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030030//cell projection organization;GO:0032956//regulation of actin cytoskeleton organization;GO:0043410//positive regulation of MAPK cascade;GO:1902018//negative regulation of cilium assembly;GO:1902749//regulation of cell cycle G2/M phase transition	--
ENSG00000185338	0.545	0.426	0.211	0.473	0.369	0.696	14	11	4	9	8	13	SOCS1	suppressor of cytokine signaling 1 [Source:HGNC Symbol;Acc:HGNC:19383]	Human Diseases;Environmental Information Processing;Genetic Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	"Cancer: overview;Signal transduction;Folding, sorting and degradation;Endocrine system;Development and regeneration;Endocrine system;Infectious disease: parasitic;Endocrine system;Endocrine and metabolic disease"	"ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04910//Insulin signaling pathway;ko04380//Osteoclast differentiation;ko04935//Growth hormone synthesis, secretion and action;ko05145//Toxoplasmosis;ko04917//Prolactin signaling pathway;ko04930//Type II diabetes mellitus"	K04694;K04694;K04694;K04694;K04694;K04694;K04694;K04694;K04694	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0031410//cytoplasmic vesicle;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0004860//protein kinase inhibitor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0019210//kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	"GO:0001817//regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0009968//negative regulation of signal transduction;GO:0010533//regulation of activation of Janus kinase activity;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0043086//negative regulation of catalytic activity;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043377//negative regulation of CD8-positive, alpha-beta T cell differentiation;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045444//fat cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0046425//regulation of receptor signaling pathway via JAK-STAT;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0071230//cellular response to amino acid stimulus"	--
ENSG00000185339	7.804	9.192	8.037	9.022	8.93	6.838	347	416	266	301	340	219	TCN2	transcobalamin 2 [Source:HGNC Symbol;Acc:HGNC:11653]	Organismal Systems	Digestive system	ko04977//Vitamin digestion and absorption	K14619	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0043202//lysosomal lumen	GO:0005515//protein binding;GO:0031419//cobalamin binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006824//cobalt ion transport;GO:0015889//cobalamin transport	--
ENSG00000185340	6.475	7.032	8.007	8.524	7.113	8.587	343	324	280	287	294	284	GAS2L1	growth arrest specific 2 like 1 [Source:HGNC Symbol;Acc:HGNC:16955]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005884//actin filament;GO:0035371//microtubule plus-end	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal anchor activity;GO:0046966//thyroid hormone receptor binding;GO:0051015//actin filament binding	GO:0001578//microtubule bundle formation;GO:0009267//cellular response to starvation;GO:0010629//negative regulation of gene expression;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051764//actin crosslink formation;GO:0097067//cellular response to thyroid hormone stimulus;GO:1904825//protein localization to microtubule plus-end	--
ENSG00000185344	5.806	6.481	5.501	4.141	4.196	5.306	598	613	403	330	394	379	ATP6V0A2	ATPase H+ transporting V0 subunit a2 [Source:HGNC Symbol;Acc:HGNC:18481]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154;K02154	"GO:0000139//Golgi membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0001669//acrosomal vesicle;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030670//phagocytic vesicle membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0043229//intracellular organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0051117//ATPase binding"	GO:0006811//ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006955//immune response;GO:0007035//vacuolar acidification;GO:0016241//regulation of macroautophagy;GO:0036295//cellular response to increased oxygen levels;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000185345	1.84	1.517	2.048	1.402	1.888	2.046	119	130	106	90	127	119	PRKN	parkin RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:8607]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Folding, sorting and degradation;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05012//Parkinson disease;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis;ko04137//Mitophagy - animal	K04556;K04556;K04556;K04556;K04556;K04556	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016235//aggresome;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0097413//Lewy body;GO:0098793//presynapse;GO:0099073//mitochondrion-derived vesicle;GO:1990452//Parkin-FBXW7-Cul1 ubiquitin ligase complex	GO:0001664//G protein-coupled receptor binding;GO:0003714//transcription corepressor activity;GO:0003779//actin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0043130//ubiquitin binding;GO:0043274//phospholipase binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding;GO:0061630//ubiquitin protein ligase activity;GO:0097602//cullin family protein binding;GO:1990381//ubiquitin-specific protease binding;GO:1990444//F-box domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0000266//mitochondrial fission;GO:0000422//autophagy of mitochondrion;GO:0000423//mitophagy;GO:0001933//negative regulation of protein phosphorylation;GO:0001963//synaptic transmission, dopaminergic;GO:0001964//startle response;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006914//autophagy;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0007417//central nervous system development;GO:0007612//learning;GO:0007626//locomotory behavior;GO:0008344//adult locomotory behavior;GO:0009966//regulation of signal transduction;GO:0010498//proteasomal protein catabolic process;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010636//positive regulation of mitochondrial fusion;GO:0010637//negative regulation of mitochondrial fusion;GO:0010821//regulation of mitochondrion organization;GO:0010906//regulation of glucose metabolic process;GO:0010994//free ubiquitin chain polymerization;GO:0014059//regulation of dopamine secretion;GO:0016236//macroautophagy;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0019538//protein metabolic process;GO:0031396//regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0031648//protein destabilization;GO:0032092//positive regulation of protein binding;GO:0032232//negative regulation of actin filament bundle assembly;GO:0032368//regulation of lipid transport;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033132//negative regulation of glucokinase activity;GO:0034620//cellular response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0035249//synaptic transmission, glutamatergic;GO:0035519//protein K29-linked ubiquitination;GO:0036503//ERAD pathway;GO:0042053//regulation of dopamine metabolic process;GO:0042415//norepinephrine metabolic process;GO:0042417//dopamine metabolic process;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043388//positive regulation of DNA binding;GO:0043524//negative regulation of neuron apoptotic process;GO:0044248//cellular catabolic process;GO:0044257//cellular protein catabolic process;GO:0044314//protein K27-linked ubiquitination;GO:0044828//negative regulation by host of viral genome replication;GO:0045732//positive regulation of protein catabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046329//negative regulation of JNK cascade;GO:0046676//negative regulation of insulin secretion;GO:0046928//regulation of neurotransmitter secretion;GO:0050804//modulation of chemical synaptic transmission;GO:0050821//protein stabilization;GO:0050896//response to stimulus;GO:0051582//positive regulation of neurotransmitter uptake;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051865//protein autoubiquitination;GO:0051881//regulation of mitochondrial membrane potential;GO:0055069//zinc ion homeostasis;GO:0060548//negative regulation of cell death;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0070050//neuron cellular homeostasis;GO:0070534//protein K63-linked ubiquitination;GO:0070585//protein localization to mitochondrion;GO:0070842//aggresome assembly;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0071287//cellular response to manganese ion;GO:0085020//protein K6-linked ubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090141//positive regulation of mitochondrial fission;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0097237//cellular response to toxic substance;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0099074//mitochondrion to lysosome transport;GO:1900407//regulation of cellular response to oxidative stress;GO:1901215//negative regulation of neuron death;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:1902283//negative regulation of primary amine oxidase activity;GO:1902530//positive regulation of protein linear polyubiquitination;GO:1902803//regulation of synaptic vesicle transport;GO:1903202//negative regulation of oxidative stress-induced cell death;GO:1903214//regulation of protein targeting to mitochondrion;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1903351//cellular response to dopamine;GO:1903377//negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903382//negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway;GO:1903542//negative regulation of exosomal secretion;GO:1903599//positive regulation of autophagy of mitochondrion;GO:1903861//positive regulation of dendrite extension;GO:1904049//negative regulation of spontaneous neurotransmitter secretion;GO:1905281//positive regulation of retrograde transport, endosome to Golgi;GO:1905366//negative regulation of intralumenal vesicle formation;GO:1905477//positive regulation of protein localization to membrane;GO:1990000//amyloid fibril formation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000378//negative regulation of reactive oxygen species metabolic process"	--
ENSG00000185347	1.723	1.688	2.34	3.086	2.422	3.089	60	45	52	62	56	72	TEDC1	tubulin epsilon and delta complex 1 [Source:HGNC Symbol;Acc:HGNC:20127]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0042995//cell projection	-	GO:0045880//positive regulation of smoothened signaling pathway	--
ENSG00000185352	0.109	0.137	0.083	0.352	0.211	0.124	17	24	10	44	29	16	HS6ST3	heparan sulfate 6-O-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:19134]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K08103	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0017095//heparan sulfate 6-O-sulfotransferase activity	"GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:1901137//carbohydrate derivative biosynthetic process"	--
ENSG00000185359	28.79	33.022	28.449	36.497	33.328	39.649	1651	1743	1260	1583	1639	1459	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate [Source:HGNC Symbol;Acc:HGNC:4897]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04144//Endocytosis;ko04145//Phagosome	K12182;K12182	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0032585//multivesicular body membrane;GO:0033565//ESCRT-0 complex;GO:0070062//extracellular exosome;GO:0097013//phagocytic vesicle lumen	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0043130//ubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046872//metal ion binding	GO:0006622//protein targeting to lysosome;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0010324//membrane invagination;GO:0010628//positive regulation of gene expression;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0016236//macroautophagy;GO:0016310//phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0036258//multivesicular body assembly;GO:0042176//regulation of protein catabolic process;GO:0043405//regulation of MAP kinase activity;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0072657//protein localization to membrane;GO:1903543//positive regulation of exosomal secretion	--
ENSG00000185361	0.682	0.641	0.65	0.29	0.479	0.677	54	51	38	17	32	39	TNFAIP8L1	TNF alpha induced protein 8 like 1 [Source:HGNC Symbol;Acc:HGNC:28279]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032007//negative regulation of TOR signaling;GO:0042981//regulation of apoptotic process	--
ENSG00000185372	0	0	0	0	0	0	0	0	0	0	0	0	OR2V1	olfactory receptor family 2 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:8280]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000185379	4.537	4.647	5.102	3.773	5.032	4.225	292	312	230	171	234	182	RAD51D	RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10871	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex"	"GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0043015//gamma-tubulin binding"	GO:0000722//telomere maintenance via recombination;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007131//reciprocal meiotic recombination;GO:0036297//interstrand cross-link repair;GO:0042148//strand invasion;GO:0051276//chromosome organization;GO:0051726//regulation of cell cycle	--
ENSG00000185385	0	0	0	0	0	0	0	0	0	0	0	0	OR7A17	olfactory receptor family 7 subfamily A member 17 [Source:HGNC Symbol;Acc:HGNC:8363]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000185386	0.76	1.21	0.887	1.573	1.6	1.472	38	61	27	51	60	41	MAPK11	mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Nervous system;Circulatory system;Infectious disease: parasitic;Cellular community - eukaryotes;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Nervous system;Signal transduction;Endocrine system;Immune system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Cancer: overview;Immune system;Endocrine system;Infectious disease: bacterial;Endocrine system;Immune system;Infectious disease: bacterial;Signal transduction	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04114//Oocyte meiosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway"	K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001649//osteoblast differentiation;GO:0006468//protein phosphorylation;GO:0010628//positive regulation of gene expression;GO:0016310//phosphorylation;GO:0032735//positive regulation of interleukin-12 production;GO:0035556//intracellular signal transduction;GO:0038066//p38MAPK cascade;GO:0051149//positive regulation of muscle cell differentiation;GO:0051403//stress-activated MAPK cascade;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060348//bone development;GO:0071347//cellular response to interleukin-1;GO:0090398//cellular senescence;GO:0098586//cellular response to virus	--
ENSG00000185404	1.536	1.399	1.445	0.9	1.146	1.193	72	73	54	34	49	44	SP140L	SP140 nuclear body protein like [Source:HGNC Symbol;Acc:HGNC:25105]	-	-	-	-	GO:0005634//nucleus;GO:0016604//nuclear body	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	SAND
ENSG00000185414	8.397	7.422	7.575	7.65	7.469	7.822	559.25	567.56	429.62	435	433.62	415.17	MRPL30	mitochondrial ribosomal protein L30 [Source:HGNC Symbol;Acc:HGNC:14036]	Genetic Information Processing	Translation	ko03010//Ribosome	K02907	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000185418	3.975	3.512	3.35	3.132	3.174	3.091	266	241	153	142	178	152	TARS3	threonyl-tRNA synthetase 3 [Source:HGNC Symbol;Acc:HGNC:24728]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01868	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004829//threonine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0140101//catalytic activity, acting on a tRNA"	GO:0006399//tRNA metabolic process;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006435//threonyl-tRNA aminoacylation;GO:0008150//biological_process;GO:0043039//tRNA aminoacylation	--
ENSG00000185420	7.416	8.827	7.903	6.945	6.575	6.324	238	280	187	167	177	148	SMYD3	SET and MYND domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15513]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K11426;K11426	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000993//RNA polymerase II complex binding;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding	GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006469//negative regulation of protein kinase activity;GO:0014904//myotube cell development;GO:0032259//methylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0034968//histone lysine methylation;GO:0045184//establishment of protein localization;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071549//cellular response to dexamethasone stimulus	--
ENSG00000185432	1.608	2.619	1.326	3.729	1.754	2.378	94	100	52	70	76	83	METTL7A	methyltransferase like 7A [Source:HGNC Symbol;Acc:HGNC:24550]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1904724//tertiary granule lumen	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000185436	1.965	1.651	1.817	2.286	2.048	2.691	158	122	116	103	142	163.08	IFNLR1	interferon lambda receptor 1 [Source:HGNC Symbol;Acc:HGNC:18584]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05140;K05140	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032002//interleukin-28 receptor complex	GO:0004896//cytokine receptor activity;GO:0005515//protein binding	GO:0002385//mucosal immune response;GO:0008285//negative regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0034342//response to type III interferon;GO:0038196//type III interferon signaling pathway;GO:0050691//regulation of defense response to virus by host;GO:0051607//defense response to virus;GO:0098586//cellular response to virus;GO:1901857//positive regulation of cellular respiration	--
ENSG00000185437	2.976	2.459	3.946	3.139	2.338	2.815	49.27	48.31	48.45	39	34.58	33.29	SH3BGR	SH3 domain binding glutamate rich protein [Source:HGNC Symbol;Acc:HGNC:10822]	-	-	-	-	GO:0005829//cytosol	GO:0017124//SH3 domain binding	GO:0065003//protein-containing complex assembly	--
ENSG00000185442	31.994	27.469	31.555	35.337	33.882	37.324	1376	1393	1251	1220	1503	1429	FAM174B	family with sequence similarity 174 member B [Source:HGNC Symbol;Acc:HGNC:34339]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007030//Golgi organization	--
ENSG00000185448	0	0	0	0	0	0	0	0	0	0	0	0	FAM47A	family with sequence similarity 47 member A [Source:HGNC Symbol;Acc:HGNC:29962]	-	-	-	-	-	-	-	--
ENSG00000185453	2.25	2.265	2.412	1.79	2.14	1.454	168	170	133	99	135	79	ZSWIM9	zinc finger SWIM-type containing 9 [Source:HGNC Symbol;Acc:HGNC:34495]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding	-	--
ENSG00000185467	0	0	0	0	0	0	0	0	0	0	0	0	KPNA7	karyopherin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:21839]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Infectious disease: viral;Translation	ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K15043;K15043;K15043	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0042564//NLS-dependent protein nuclear import complex	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0001824//blastocyst development;GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0015031//protein transport;GO:1902466//positive regulation of histone H3-K27 trimethylation	--
ENSG00000185475	41.665	42.431	39.765	48.433	45.458	45.64	887.17	883.29	630.64	763.56	826.45	691.2	TMEM179B	transmembrane protein 179B [Source:HGNC Symbol;Acc:HGNC:33744]	-	-	-	-	GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0030667//secretory granule membrane;GO:0035577//azurophil granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding	-	--
ENSG00000185477	0.841	0.652	0.507	0.25	0.432	0.456	245	149	109	54	96	87	GPRIN3	GPRIN family member 3 [Source:HGNC Symbol;Acc:HGNC:27733]	-	-	-	-	GO:0005886//plasma membrane	-	GO:0031175//neuron projection development	--
ENSG00000185479	0	0	0	0	0	0	0	0	0	0	0	0	KRT6B	keratin 6B [Source:HGNC Symbol;Acc:HGNC:6444]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0007398//ectoderm development	--
ENSG00000185480	1.042	0.712	0.509	0.506	0.279	0.651	45	39	20	16	12	24	PARPBP	PARP1 binding protein [Source:HGNC Symbol;Acc:HGNC:26074]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:2000042//negative regulation of double-strand break repair via homologous recombination	--
ENSG00000185482	0.117	0.263	0.164	0.064	0.072	0.131	4	5	2	1	2	2	STAC3	SH3 and cysteine rich domain 3 [Source:HGNC Symbol;Acc:HGNC:28423]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0030315//T-tubule;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042383//sarcolemma;GO:0045202//synapse	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0003009//skeletal muscle contraction;GO:0007274//neuromuscular synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1903078//positive regulation of protein localization to plasma membrane	--
ENSG00000185483	3.45	3.177	2.548	2.631	2.988	3.859	355	320	218	223	283	312	ROR1	receptor tyrosine kinase like orphan receptor 1 [Source:HGNC Symbol;Acc:HGNC:10256]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K05122	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0043679//axon terminus	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017147//Wnt-protein binding;GO:0042813//Wnt-activated receptor activity;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway"	"GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007605//sensory perception of sound;GO:0010976//positive regulation of neuron projection development;GO:0014002//astrocyte development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048839//inner ear development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060071//Wnt signaling pathway, planar cell polarity pathway"	--
ENSG00000185499	1.643	2.411	1.773	1.211	1.509	2.778	54	76	35	31	44	48	MUC1	"mucin 1, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7508]"	-	-	-	-	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0002039//p53 binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding	"GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0090240//positive regulation of histone H4 acetylation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator"	--
ENSG00000185504	12.28	13.308	13.634	14.69	15.659	12.691	901	976	754	790	925	687	FAAP100	FA core complex associated protein 100 [Source:HGNC Symbol;Acc:HGNC:26171]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10993	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043240//Fanconi anaemia nuclear complex	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0036297//interstrand cross-link repair	--
ENSG00000185507	4.477	4.645	5.806	6.462	5.389	6.887	161	157	142	151	152	160	IRF7	interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447;K09447	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010008//endosome membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002376//immune system process;GO:0002819//regulation of adaptive immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0009615//response to virus;GO:0010468//regulation of gene expression;GO:0016064//immunoglobulin mediated immune response;GO:0019043//establishment of viral latency;GO:0032479//regulation of type I interferon production;GO:0032481//positive regulation of type I interferon production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0034127//regulation of MyD88-independent toll-like receptor signaling pathway;GO:0039530//MDA-5 signaling pathway;GO:0045087//innate immune response;GO:0045655//regulation of monocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050776//regulation of immune response;GO:0051607//defense response to virus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:2000110//negative regulation of macrophage apoptotic process"	IRF
ENSG00000185513	1.804	1.083	0.857	0.996	1.98	1.464	101	76	58	60	105	76	L3MBTL1	L3MBTL histone methyl-lysine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15905]	-	-	-	-	GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0061793//chromatin lock complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031491//nucleosome binding;GO:0032093//SAM domain binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007088//regulation of mitotic nuclear division;GO:0030097//hemopoiesis;GO:0031507//heterochromatin assembly;GO:0045652//regulation of megakaryocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle"	zf-C2HC
ENSG00000185515	7.339	5.825	5.785	3.905	5.025	5.675	405	307	231	158	222	209	BRCC3	BRCA1/BRCA2-containing complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:24185]	Organismal Systems;Genetic Information Processing	Immune system;Replication and repair	ko04621//NOD-like receptor signaling pathway;ko03440//Homologous recombination	K11864;K11864	GO:0000151//ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0070531//BRCA1-A complex;GO:0070552//BRISC complex	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0030234//enzyme regulator activity;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0070122//isopeptidase activity;GO:0140492//metal-dependent deubiquitinase activity	GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006302//double-strand break repair;GO:0006325//chromatin organization;GO:0006508//proteolysis;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010165//response to X-ray;GO:0010212//response to ionizing radiation;GO:0016579//protein deubiquitination;GO:0035518//histone H2A monoubiquitination;GO:0044818//mitotic G2/M transition checkpoint;GO:0045739//positive regulation of DNA repair;GO:0050790//regulation of catalytic activity;GO:0051301//cell division;GO:0051865//protein autoubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0070537//histone H2A K63-linked deubiquitination;GO:0071479//cellular response to ionizing radiation;GO:2000001//regulation of DNA damage checkpoint	--
ENSG00000185518	14.476	14.062	15.935	12.097	14.02	12.469	1717	1731	1375	1131	1429	1131	SV2B	synaptic vesicle glycoprotein 2B [Source:HGNC Symbol;Acc:HGNC:16874]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06258	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0055085//transmembrane transport	--
ENSG00000185519	0.392	0.363	0.228	0.265	0.166	0.347	14	13	6	7	5	9	FAM131C	family with sequence similarity 131 member C [Source:HGNC Symbol;Acc:HGNC:26717]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185522	0.657	0.91	0.878	1.513	0.805	0.972	23	27	20	39	29	26	LMNTD2	lamin tail domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28561]	-	-	-	-	GO:0005638//lamin filament	GO:0005515//protein binding;GO:0030527//structural constituent of chromatin	GO:0010847//regulation of chromatin assembly	--
ENSG00000185523	0	0	0	0	0	0	0	0	0	0	0	0	SPATA45	spermatogenesis associated 45 [Source:HGNC Symbol;Acc:HGNC:33709]	-	-	-	-	-	-	-	--
ENSG00000185527	0.976	1.496	2.18	1.449	1.444	0.805	20	26	33	22	25	12	PDE6G	phosphodiesterase 6G [Source:HGNC Symbol;Acc:HGNC:8789]	Metabolism;Metabolism;Organismal Systems	Global and overview maps;Nucleotide metabolism;Sensory system	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko04744//Phototransduction	K13759;K13759;K13759	GO:0005886//plasma membrane;GO:0042622//photoreceptor outer segment membrane;GO:0097381//photoreceptor disc membrane	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0030507//spectrin binding;GO:0030553//cGMP binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	GO:0007601//visual perception;GO:0043086//negative regulation of catalytic activity;GO:0043410//positive regulation of MAPK cascade;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus	--
ENSG00000185532	8.986	7.348	6.754	4.171	5.969	5.825	969	676	538	386	497	434	PRKG1	protein kinase cGMP-dependent 1 [Source:HGNC Symbol;Acc:HGNC:9414]	Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems	Sensory system;Environmental adaptation;Signal transduction;Circulatory system;Immune system;Environmental adaptation;Digestive system;Cellular community - eukaryotes;Endocrine system;Nervous system	ko04740//Olfactory transduction;ko04714//Thermogenesis;ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04713//Circadian entrainment;ko04970//Salivary secretion;ko04540//Gap junction;ko04923//Regulation of lipolysis in adipocytes;ko04730//Long-term depression	K07376;K07376;K07376;K07376;K07376;K07376;K07376;K07376;K07376;K07376	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004692//cGMP-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030553//cGMP binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0016358//dendrite development;GO:0019934//cGMP-mediated signaling;GO:0030036//actin cytoskeleton organization;GO:0030900//forebrain development;GO:0043087//regulation of GTPase activity;GO:0045986//negative regulation of smooth muscle contraction;GO:0060087//relaxation of vascular associated smooth muscle;GO:0090331//negative regulation of platelet aggregation;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration	--
ENSG00000185551	18.361	15.975	14.961	17.048	15.504	17.27	995	870	701	814	851	800	NR2F2	nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001972//retinoic acid binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0001764//neuron migration;GO:0001893//maternal placenta development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001945//lymph vessel development;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007519//skeletal muscle tissue development;GO:0008585//female gonad development;GO:0009566//fertilization;GO:0009952//anterior/posterior pattern specification;GO:0009956//radial pattern formation;GO:0010596//negative regulation of endothelial cell migration;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0030900//forebrain development;GO:0032355//response to estradiol;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0048856//anatomical structure development;GO:0060173//limb development;GO:0060674//placenta blood vessel development;GO:0060707//trophoblast giant cell differentiation;GO:0060838//lymphatic endothelial cell fate commitment"	RXR-like
ENSG00000185559	0.01	0.083	0.099	0.014	0	0	1	4	2	1	0	0	DLK1	delta like non-canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2907]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0045746//negative regulation of Notch signaling pathway	--
ENSG00000185561	1.712	1.451	1.409	0.819	1.047	0.923	209	178	127	74	108	82	TLCD2	TLC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33522]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007009//plasma membrane organization;GO:0055088//lipid homeostasis;GO:0055091//phospholipid homeostasis;GO:0071709//membrane assembly;GO:0097035//regulation of membrane lipid distribution	--
ENSG00000185565	16.588	14.248	18.064	14.721	18.507	17.179	1827	1596	1439	1148	1584	1356	LSAMP	limbic system associated membrane protein [Source:HGNC Symbol;Acc:HGNC:6705]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007399//nervous system development	--
ENSG00000185567	18.431	17.872	14.348	10.898	12.673	8.922	4902	5194	2699	2081	2861	1872	AHNAK2	AHNAK nucleoprotein 2 [Source:HGNC Symbol;Acc:HGNC:20125]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23934	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030315//T-tubule;GO:0042383//sarcolemma	GO:0005515//protein binding	GO:0043484//regulation of RNA splicing	--
ENSG00000185585	0.753	0.768	0.605	0.853	0.681	0.525	91	103	60	54	74	51	OLFML2A	olfactomedin like 2A [Source:HGNC Symbol;Acc:HGNC:27270]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0042802//identical protein binding;GO:0050840//extracellular matrix binding	GO:0007165//signal transduction;GO:0030198//extracellular matrix organization	--
ENSG00000185591	12.196	12.206	12.792	11.202	13.091	13.751	1666	1731	1335	1130	1476	1404	SP1	Sp1 transcription factor [Source:HGNC Symbol;Acc:HGNC:11205]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems	Cancer: overview;Neurodegenerative disease;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Endocrine and metabolic disease;Cancer: specific types;Neurodegenerative disease;Endocrine system;Endocrine system;Cancer: overview;Drug resistance: antineoplastic;Signal transduction;Transport and catabolism;Endocrine system	"ko05200//Pathways in cancer;ko05016//Huntington disease;ko05202//Transcriptional misregulation in cancer;ko05163//Human cytomegalovirus infection;ko05415//Diabetic cardiomyopathy;ko04934//Cushing syndrome;ko05224//Breast cancer;ko05017//Spinocerebellar ataxia;ko04915//Estrogen signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko05231//Choline metabolism in cancer;ko01522//Endocrine resistance;ko04350//TGF-beta signaling pathway;ko04137//Mitophagy - animal;ko04927//Cortisol synthesis and secretion"	K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684;K04684	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex;GO:0032993//protein-DNA complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0035035//histone acetyltransferase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0071837//HMG box domain binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0032869//cellular response to insulin stimulus;GO:0033194//response to hydroperoxide;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043923//positive regulation by host of viral transcription;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:1902004//positive regulation of amyloid-beta formation;GO:1904828//positive regulation of hydrogen sulfide biosynthetic process;GO:1905564//positive regulation of vascular endothelial cell proliferation"	zf-C2H2
ENSG00000185608	29.355	30.171	32.288	27.469	25.618	25.916	453	468	368	314	334	291	MRPL40	mitochondrial ribosomal protein L40 [Source:HGNC Symbol;Acc:HGNC:14491]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0009653//anatomical structure morphogenesis;GO:0032543//mitochondrial translation	--
ENSG00000185610	0.464	0.564	0.558	0.278	0.224	0.283	27	33	24	12	11	12	DBX2	developing brain homeobox 2 [Source:HGNC Symbol;Acc:HGNC:33186]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000185614	0.047	0.139	0.253	0.315	0.11	0	1	3	4	5	2	0	INKA1	inka box actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:32480]	-	-	-	-	GO:0005634//nucleus	GO:0030291//protein serine/threonine kinase inhibitor activity	GO:0021915//neural tube development;GO:0043086//negative regulation of catalytic activity	--
ENSG00000185615	1.508	2.713	1.587	3.614	3.494	3.964	47	60	41	68	87	70	PDIA2	protein disulfide isomerase family A member 2 [Source:HGNC Symbol;Acc:HGNC:14180]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0003756//protein disulfide isomerase activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015035//protein-disulfide reductase activity;GO:0015036//disulfide oxidoreductase activity;GO:0016853//isomerase activity	GO:0006457//protein folding;GO:0006621//protein retention in ER lumen;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress	--
ENSG00000185619	11.437	12.198	9.26	10.992	10.88	11.554	895	874	567	542	675	556	PCGF3	polycomb group ring finger 3 [Source:HGNC Symbol;Acc:HGNC:10066]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11488	GO:0000805//X chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0036353//histone H2A-K119 monoubiquitination;GO:0060819//inactivation of X chromosome by genetic imprinting	--
ENSG00000185621	2.205	1.876	2.087	1.602	1.756	1.557	325	264	198	170	218	167	LMLN	leishmanolysin like peptidase [Source:HGNC Symbol;Acc:HGNC:15991]	-	-	-	-	GO:0005737//cytoplasm;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0051301//cell division	--
ENSG00000185624	270.103	291.115	268.007	287.717	273.878	242.939	13520	14613	9906	10621	11579	8857	P4HB	prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09580	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0030027//lamellipodium;GO:0032991//protein-containing complex;GO:0034663//endoplasmic reticulum chaperone complex;GO:0042470//melanosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003756//protein disulfide isomerase activity;GO:0003779//actin binding;GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016853//isomerase activity;GO:0016972//thiol oxidase activity;GO:0019899//enzyme binding;GO:0044877//protein-containing complex binding;GO:0046982//protein heterodimerization activity;GO:0051213//dioxygenase activity	GO:0006457//protein folding;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0035722//interleukin-12-mediated signaling pathway;GO:0038155//interleukin-23-mediated signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0046598//positive regulation of viral entry into host cell;GO:0071456//cellular response to hypoxia;GO:0098761//cellular response to interleukin-7;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000185627	32.006	34.585	37.724	33.299	35.321	38.427	1042	1130	904	797	978	876	PSMD13	"proteasome 26S subunit, non-ATPase 13 [Source:HGNC Symbol;Acc:HGNC:9558]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03039;K03039;K03039;K03039;K03039;K03039;K03039;K03039;K03039	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen"	GO:0005198//structural molecule activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007127//meiosis I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000185630	16.826	15.002	16.442	15.045	13.074	13.771	1583	1479	1161	995	1191	978	PBX1	PBX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8632]	Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Endocrine and metabolic disease;Endocrine system	ko05202//Transcriptional misregulation in cancer;ko04934//Cushing syndrome;ko04927//Cortisol synthesis and secretion	K09355;K09355;K09355	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001222//transcription corepressor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0140297//DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001654//eye development;GO:0001655//urogenital system development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001779//natural killer cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006694//steroid biosynthetic process;GO:0007420//brain development;GO:0007548//sex differentiation;GO:0008284//positive regulation of cell population proliferation;GO:0009887//animal organ morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0030154//cell differentiation;GO:0030278//regulation of ossification;GO:0030325//adrenal gland development;GO:0030326//embryonic limb morphogenesis;GO:0035162//embryonic hemopoiesis;GO:0042127//regulation of cell population proliferation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048536//spleen development;GO:0048538//thymus development;GO:0048568//embryonic organ development;GO:0048666//neuron development;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000185633	4.075	2.806	3.623	5.177	2.805	2.507	81	59	53	75	47	37	NDUFA4L2	NDUFA4 mitochondrial complex associated like 2 [Source:HGNC Symbol;Acc:HGNC:29836]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948	GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000185634	0.217	0.243	0.122	0.191	0.011	0.04	9	8	4	4	1	3	SHC4	SHC adaptor protein 4 [Source:HGNC Symbol;Acc:HGNC:16743]	Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Signal transduction;Signal transduction;Cellular community - eukaryotes;Immune system;Substance dependence;Immune system;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Endocrine system;Endocrine system;Nervous system;Endocrine system;Drug resistance: antineoplastic;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Endocrine system	"ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko01522//Endocrine resistance;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway"	K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449;K17449	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding	GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0035556//intracellular signal transduction;GO:0048863//stem cell differentiation	--
ENSG00000185640	0	0	0	0	0	0	0	0	0	0	0	0	KRT79	keratin 79 [Source:HGNC Symbol;Acc:HGNC:28930]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0019899//enzyme binding	-	--
ENSG00000185650	50.731	46.641	47.41	39.797	48.702	47.422	2763	2621	1928	1720	2303	2084	ZFP36L1	ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K18753	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990904//ribonucleoprotein complex	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0046872//metal ion binding;GO:0071889//14-3-3 protein binding	"GO:0000165//MAPK cascade;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0001570//vasculogenesis;GO:0003342//proepicardium development;GO:0006397//mRNA processing;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0007507//heart development;GO:0008283//cell population proliferation;GO:0009611//response to wounding;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010837//regulation of keratinocyte proliferation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0021915//neural tube development;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0031440//regulation of mRNA 3'-end processing;GO:0032869//cellular response to insulin stimulus;GO:0033077//T cell differentiation in thymus;GO:0035264//multicellular organism growth;GO:0038066//p38MAPK cascade;GO:0043488//regulation of mRNA stability;GO:0043491//protein kinase B signaling;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045577//regulation of B cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045616//regulation of keratinocyte differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0045661//regulation of myoblast differentiation;GO:0048382//mesendoderm development;GO:0048568//embryonic organ development;GO:0051028//mRNA transport;GO:0060710//chorio-allantoic fusion;GO:0060712//spongiotrophoblast layer development;GO:0061014//positive regulation of mRNA catabolic process;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0070371//ERK1 and ERK2 cascade;GO:0071320//cellular response to cAMP;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071456//cellular response to hypoxia;GO:0071472//cellular response to salt stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072091//regulation of stem cell proliferation;GO:0097403//cellular response to raffinose;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:1902172//regulation of keratinocyte apoptotic process;GO:1904582//positive regulation of intracellular mRNA localization"	zf-CCCH
ENSG00000185651	37.17	37.296	39.737	39.045	39.095	39.977	2189	2205	1661	1685	1946	1718	UBE2L3	ubiquitin conjugating enzyme E2 L3 [Source:HGNC Symbol;Acc:HGNC:12488]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K04552;K04552;K04552	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity;GO:0097027//ubiquitin-protein transferase activator activity	"GO:0000209//protein polyubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008283//cell population proliferation;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0044770//cell cycle phase transition;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0070979//protein K11-linked ubiquitination;GO:0071383//cellular response to steroid hormone stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:1903955//positive regulation of protein targeting to mitochondrion"	--
ENSG00000185652	0.431	0.407	0.584	0.995	1.319	1.186	12	11	12	20	31	24	NTF3	neurotrophin 3 [Source:HGNC Symbol;Acc:HGNC:8023]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Nervous system	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04722//Neurotrophin signaling pathway	K04356;K04356;K04356;K04356	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0008021//synaptic vesicle;GO:0030424//axon;GO:0030425//dendrite	GO:0005102//signaling receptor binding;GO:0005163//nerve growth factor receptor binding;GO:0005165//neurotrophin receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity	GO:0002092//positive regulation of receptor internalization;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0007613//memory;GO:0008284//positive regulation of cell population proliferation;GO:0021675//nerve development;GO:0030335//positive regulation of cell migration;GO:0032148//activation of protein kinase B activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038180//nerve growth factor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0048812//neuron projection morphogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050804//modulation of chemical synaptic transmission;GO:0050918//positive chemotaxis;GO:0050930//induction of positive chemotaxis;GO:0090630//activation of GTPase activity;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000185658	8.443	7.604	8.312	6.875	6.797	5.699	1112	734	569	439	582	458	BRWD1	bromodomain and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:12760]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape	--
ENSG00000185662	0	0	0	0	0	0	0	0	0	0	0	0	SMIM23	small integral membrane protein 23 [Source:HGNC Symbol;Acc:HGNC:34440]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000185664	6952.387	7324.298	7764.374	8762.501	8172.189	8358.997	216386	236240	173388	198881	215488	184579	PMEL	premelanosome protein [Source:HGNC Symbol;Acc:HGNC:10880]	-	-	-	-	GO:0005576//extracellular region;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032585//multivesicular body membrane;GO:0042470//melanosome	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032438//melanosome organization;GO:0042438//melanin biosynthetic process	--
ENSG00000185666	0.172	0.213	0.29	0.273	0.167	0.362	28	35	35	33	23	43	SYN3	synapsin III [Source:HGNC Symbol;Acc:HGNC:11496]	-	-	-	-	GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0098793//presynapse;GO:0098850//extrinsic component of synaptic vesicle membrane;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0005524//ATP binding	"GO:0007269//neurotransmitter secretion;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0097091//synaptic vesicle clustering;GO:0099504//synaptic vesicle cycle"	--
ENSG00000185668	0.033	0.032	0.022	0.022	0	0	2	2	1	1	0	0	POU3F1	POU class 3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9214]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0008366//axon ensheathment;GO:0008544//epidermis development;GO:0010628//positive regulation of gene expression;GO:0014044//Schwann cell development;GO:0022011//myelination in peripheral nervous system;GO:0030216//keratinocyte differentiation;GO:0030900//forebrain development;GO:0042552//myelination;GO:0045893//positive regulation of transcription, DNA-templated"	Pou
ENSG00000185669	0.139	0.276	0.038	0.299	0.098	0	5	10	1	8	3	0	SNAI3	snail family transcriptional repressor 3 [Source:HGNC Symbol;Acc:HGNC:18411]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005507//copper ion binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000185670	1.258	1.398	1.456	1.147	1.219	2.225	77	86	53	52	63	52	ZBTB3	zinc finger and BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22918]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000185674	0	0	0	0	0	0	0	0	0	0	0	0	LYG2	lysozyme g2 [Source:HGNC Symbol;Acc:HGNC:29615]	-	-	-	-	GO:0005576//extracellular region	"GO:0003796//lysozyme activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0008152//metabolic process;GO:0009253//peptidoglycan catabolic process;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000185681	1.912	2.166	2.054	0.912	0.926	1.511	24	29	20	8	10	13	MORN5	MORN repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:17841]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185686	0	0.085	0	0	0	0	0	1	0	0	0	0	PRAME	PRAME nuclear receptor transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:9336]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:0042974//retinoic acid receptor binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	"GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0040008//regulation of growth;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048387//negative regulation of retinoic acid receptor signaling pathway"	--
ENSG00000185697	0.816	0.529	0.329	0.246	0.309	0.265	60	53	26	12	19	14	MYBL1	MYB proto-oncogene like 1 [Source:HGNC Symbol;Acc:HGNC:7547]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1990511//piRNA biosynthetic process"	MYB
ENSG00000185716	5.972	4.058	5.537	4.269	5.675	5.15	409	314	249	254	280	275	MOSMO	modulator of smoothened [Source:HGNC Symbol;Acc:HGNC:27087]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K23663	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	-	GO:0030154//cell differentiation;GO:0031647//regulation of protein stability;GO:0045664//regulation of neuron differentiation;GO:0045879//negative regulation of smoothened signaling pathway	--
ENSG00000185721	23.215	25.918	21.924	25.13	19.844	20.623	791	889	550	623.46	579	518	DRG1	developmentally regulated GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3029]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005844//polysome;GO:0016020//membrane;GO:0016604//nuclear body	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0008134//transcription factor binding;GO:0016787//hydrolase activity;GO:0030955//potassium ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0002181//cytoplasmic translation;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0031116//positive regulation of microtubule polymerization;GO:1901673//regulation of mitotic spindle assembly"	--
ENSG00000185722	18.441	19.599	19.831	16.226	18.089	18.064	2741	2787	2158	1746	2203	1965	ANKFY1	ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763]	-	-	-	-	GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030904//retromer complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044354//macropinosome;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:1901981//phosphatidylinositol phosphate binding	"GO:0006897//endocytosis;GO:0016197//endosomal transport;GO:0034058//endosomal vesicle fusion;GO:0042147//retrograde transport, endosome to Golgi;GO:0048549//positive regulation of pinocytosis;GO:0090160//Golgi to lysosome transport"	--
ENSG00000185728	27.839	23.234	21.712	18.956	21.096	24.202	2577	2130	1612	1408	1686	1626	YTHDF3	YTH N6-methyladenosine RNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:26465]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:1990247//N6-methyladenosine-containing RNA binding	GO:0034063//stress granule assembly;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation;GO:0045948//positive regulation of translational initiation;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061157//mRNA destabilization;GO:0070925//organelle assembly;GO:1901163//regulation of trophoblast cell migration	--
ENSG00000185730	3.003	2.955	3.3	2.224	2.466	2.875	170	165	137	103	132	137	ZNF696	zinc finger protein 696 [Source:HGNC Symbol;Acc:HGNC:25872]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000185736	0	0	0.008	0	0	0	0	0	1	0	0	0	ADARB2	adenosine deaminase RNA specific B2 (inactive) [Source:HGNC Symbol;Acc:HGNC:227]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0003727//single-stranded RNA binding;GO:0004000//adenosine deaminase activity;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006382//adenosine to inosine editing;GO:0006396//RNA processing;GO:0006397//mRNA processing	--
ENSG00000185737	4.441	3.961	4.011	4.79	5.509	3.501	240	244	182	217	256	159	NRG3	neuregulin 3 [Source:HGNC Symbol;Acc:HGNC:7999]	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko04012//ErbB signaling pathway	K05457;K05457	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	GO:0005102//signaling receptor binding;GO:0008083//growth factor activity;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding;GO:0045499//chemorepellent activity;GO:0048018//receptor ligand activity	GO:0001558//regulation of cell growth;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0021842//chemorepulsion involved in interneuron migration from the subpallium to the cortex;GO:0030879//mammary gland development;GO:0035556//intracellular signal transduction;GO:0038130//ERBB4 signaling pathway;GO:0048513//animal organ development;GO:0050804//modulation of chemical synaptic transmission;GO:0060596//mammary placode formation;GO:2001223//negative regulation of neuron migration	--
ENSG00000185739	0.011	0	0	0	0	0	1	0	0	0	0	0	SRL	sarcalumenin [Source:HGNC Symbol;Acc:HGNC:11295]	-	-	-	-	GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006897//endocytosis;GO:0016197//endosomal transport	--
ENSG00000185742	0.058	0.016	0.056	0.033	0.078	0.023	7	2	5	3	8	2	C11orf87	chromosome 11 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:33788]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000185745	3.99	4.471	3.52	3.571	3.688	4.436	356	401	232	236	278	288	IFIT1	interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407]	Human Diseases	Infectious disease: viral	ko05160//Hepatitis C	K14217	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043657//host cell	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0002376//immune system process;GO:0009615//response to virus;GO:0019060//intracellular transport of viral protein in host cell;GO:0032091//negative regulation of protein binding;GO:0045070//positive regulation of viral genome replication;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0050688//regulation of defense response to virus;GO:0051097//negative regulation of helicase activity;GO:0051607//defense response to virus;GO:0071357//cellular response to type I interferon;GO:0071360//cellular response to exogenous dsRNA;GO:0140374//antiviral innate immune response	--
ENSG00000185753	2.113	2.463	2.326	1.574	2.194	2.209	189	215	150	99	163	142	CXorf38	chromosome X open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28589]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185758	0	0	0	0	0	0.2	0	0	0	0	0	2	CLDN24	claudin 24 [Source:HGNC Symbol;Acc:HGNC:37200]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity	GO:0007155//cell adhesion;GO:0070830//bicellular tight junction assembly	--
ENSG00000185760	0.415	0.503	0.23	0.437	0.551	0.712	48	46	13	38	47	44	KCNQ5	potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299]	Organismal Systems	Nervous system	ko04725//Cholinergic synapse	K04930	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030118//clathrin coat	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015075//ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000185761	10.837	13.403	16.867	17.346	15.511	14.851	404	487	437	439	495	490	ADAMTSL5	ADAMTS like 5 [Source:HGNC Symbol;Acc:HGNC:27912]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization	--
ENSG00000185774	0.189	0.097	0.257	0.239	0.208	0	8.22	2	3	6.18	5.33	0	KCNIP4	potassium voltage-gated channel interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:30083]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0072659//protein localization to plasma membrane;GO:1901379//regulation of potassium ion transmembrane transport	--
ENSG00000185775	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31A6	SPATA31 subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:32006]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000185787	254.153	242.388	237.241	219.083	203.294	218.592	6574	6437	4700	4150	4427	4136	MORF4L1	mortality factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:16989]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0016607//nuclear speck;GO:0035267//NuA4 histone acetyltransferase complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding	"GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell population proliferation;GO:0016573//histone acetylation;GO:0016575//histone deacetylation;GO:0040008//regulation of growth;GO:0042981//regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000779//regulation of double-strand break repair"	--
ENSG00000185792	0	0	0	0	0	0	0	0	0	0	0	0	NLRP9	NLR family pyrin domain containing 9 [Source:HGNC Symbol;Acc:HGNC:22941]	-	-	-	-	GO:0005737//cytoplasm;GO:0061702//inflammasome complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0032741//positive regulation of interleukin-18 production;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0070269//pyroptosis	--
ENSG00000185798	3.514	2.766	3.081	1.92	1.985	2.997	97	80	50	44	50	64	WDR53	WD repeat domain 53 [Source:HGNC Symbol;Acc:HGNC:28786]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000185800	10.074	12.941	13.404	11.209	12.868	13.804	694	761	662	557	720	622	DMWD	"DM1 locus, WD repeat containing [Source:HGNC Symbol;Acc:HGNC:2936]"	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0003674//molecular_function;GO:0005515//protein binding	-	--
ENSG00000185803	15.165	16.208	17.029	21.579	19.174	17.232	662	704	551	681	707	539	SLC52A2	solute carrier family 52 member 2 [Source:HGNC Symbol;Acc:HGNC:30224]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0032217//riboflavin transmembrane transporter activity;GO:0062124//4-hydroxybutyrate receptor activity	GO:0006771//riboflavin metabolic process;GO:0032218//riboflavin transport;GO:0046718//viral entry into host cell	--
ENSG00000185808	19.696	18.108	18.09	18.953	16.941	21.941	337	295	225	242	238	272	PIGP	phosphatidylinositol glycan anchor biosynthesis class P [Source:HGNC Symbol;Acc:HGNC:3046]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K03861;K03861	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000185811	0.114	0.144	0.096	0.218	0.161	0.203	12	16	7	18	13	8	IKZF1	IKAROS family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13176]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0007498//mesoderm development;GO:0030098//lymphocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000185813	10.571	15.217	16.176	19.049	18.431	20.891	512.94	618.19	431.84	645.13	702.93	695.7	PCYT2	"phosphate cytidylyltransferase 2, ethanolamine [Source:HGNC Symbol;Acc:HGNC:8756]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00440//Phosphonate and phosphinate metabolism	K00967;K00967;K00967	GO:0005575//cellular_component;GO:0005789//endoplasmic reticulum membrane	GO:0003824//catalytic activity;GO:0004306//ethanolamine-phosphate cytidylyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0009058//biosynthetic process	--
ENSG00000185818	14.194	13.346	14.465	18.26	16.565	17.758	1783	1685	1342	1699	1758	1623	NAT8L	N-acetyltransferase 8 like [Source:HGNC Symbol;Acc:HGNC:26742]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	"ko01100//Metabolic pathways;ko00250//Alanine, aspartate and glutamate metabolism"	K18309;K18309	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0017188//aspartate N-acetyltransferase activity	GO:0009066//aspartate family amino acid metabolic process	--
ENSG00000185821	0	0	0	0	0	0	0	0	0	0	0	0	OR6C76	olfactory receptor family 6 subfamily C member 76 [Source:HGNC Symbol;Acc:HGNC:31305]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000185823	0	0	0.009	0	0	0	0	0	1	0	0	0	NPAP1	nuclear pore associated protein 1 [Source:HGNC Symbol;Acc:HGNC:1190]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003674//molecular_function;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000185825	110.47	110.665	123.23	145.526	128.041	127.04	2948	2950	2411	2871	2877	2472	BCAP31	B cell receptor associated protein 31 [Source:HGNC Symbol;Acc:HGNC:16695]	Human Diseases;Genetic Information Processing	"Infectious disease: viral;Folding, sorting and degradation"	ko05165//Human papillomavirus infection;ko04141//Protein processing in endoplasmic reticulum	K14009;K14009	GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0044233//mitochondria-associated endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0097038//perinuclear endoplasmic reticulum	GO:0005515//protein binding;GO:0042288//MHC class I protein binding;GO:0044877//protein-containing complex binding	"GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006915//apoptotic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007283//spermatogenesis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0034976//response to endoplasmic reticulum stress;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0070973//protein localization to endoplasmic reticulum exit site;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1904154//positive regulation of retrograde protein transport, ER to cytosol;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000185829	3.239	2.345	2.618	2.42	2.644	2.097	306.4	200.56	210.2	166.34	242.91	139.66	ARL17A	ADP ribosylation factor like GTPase 17A [Source:HGNC Symbol;Acc:HGNC:24096]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000185838	1.263	1.26	1.344	1.405	1.677	1.307	39.99	36.74	34.98	32.45	49	30.36	GNB1L	G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397]	-	-	-	-	GO:0009898//cytoplasmic side of plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0035556//intracellular signal transduction	--
ENSG00000185842	1.415	2.022	1.909	1.28	2.127	1.866	52	58	46	28	59	46	DNAH14	dynein axonemal heavy chain 14 [Source:HGNC Symbol;Acc:HGNC:2945]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0030286//dynein complex;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement;GO:0060285//cilium-dependent cell motility	--
ENSG00000185860	0.119	0.359	0.064	0.013	0.055	0.027	8	12	2	1	4	2	CCDC190	coiled-coil domain containing 190 [Source:HGNC Symbol;Acc:HGNC:28736]	-	-	-	-	-	-	-	--
ENSG00000185862	0	0	0	0	0.088	0	0	0	0	0	3	0	EVI2B	ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:HGNC:3500]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0030854//positive regulation of granulocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045660//positive regulation of neutrophil differentiation;GO:0051726//regulation of cell cycle;GO:0061515//myeloid cell development;GO:2000035//regulation of stem cell division	--
ENSG00000185863	0	0	0	0	0	0	0	0	0	0	0	0	TMEM210	transmembrane protein 210 [Source:HGNC Symbol;Acc:HGNC:34059]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000185864	5.79	2.299	2.425	7.265	4.148	4.989	123.81	53.72	38.96	103.27	75.11	87.41	NPIPB4	nuclear pore complex interacting protein family member B4 [Source:HGNC Symbol;Acc:HGNC:41985]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000185869	0.358	0.372	0.144	0.144	0.367	0.2	37	39	11	11	32	15	ZNF829	zinc finger protein 829 [Source:HGNC Symbol;Acc:HGNC:34032]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000185873	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS11B	transmembrane serine protease 11B [Source:HGNC Symbol;Acc:HGNC:25398]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0008150//biological_process	--
ENSG00000185875	2.896	2.797	2.777	2.439	2.581	2.593	225	219	159	141	169	147	THNSL1	threonine synthase like 1 [Source:HGNC Symbol;Acc:HGNC:26160]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000185880	1.513	1.929	1.786	1.571	1.676	1.866	78	100	68	60	73	70	TRIM69	tripartite motif containing 69 [Source:HGNC Symbol;Acc:HGNC:17857]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0016567//protein ubiquitination	--
ENSG00000185883	206.331	211.804	226.187	275.983	241.096	226.824	4292	4495	3476	4179.98	4421	3405	ATP6V0C	ATPase H+ transporting V0 subunit c [Source:HGNC Symbol;Acc:HGNC:855]	Metabolism;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Metabolism;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Infectious disease: bacterial;Transport and catabolism;Immune disease;Energy metabolism;Transport and catabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko05152//Tuberculosis;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko00190//Oxidative phosphorylation;ko04142//Lysosome;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02155;K02155;K02155;K02155;K02155;K02155;K02155;K02155;K02155;K02155;K02155	"GO:0000139//Golgi membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0005773//vacuole;GO:0005774//vacuolar membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0035577//azurophil granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0031625//ubiquitin protein ligase binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0015986//ATP synthesis coupled proton transport;GO:0016241//regulation of macroautophagy;GO:0030177//positive regulation of Wnt signaling pathway;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:1902600//proton transmembrane transport	--
ENSG00000185885	39.445	40.717	44.693	36.13	27.857	47.535	562.5	537.39	453.26	331.05	329.21	428.29	IFITM1	interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412]	Organismal Systems	Immune system	ko04662//B cell receptor signaling pathway	K19831	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding	GO:0001503//ossification;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0009615//response to virus;GO:0030336//negative regulation of cell migration;GO:0034341//response to interferon-gamma;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045669//positive regulation of osteoblast differentiation;GO:0046597//negative regulation of viral entry into host cell;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway	--
ENSG00000185888	0	0	0	0	0	0	0	0	0	0	0	0	PRSS38	serine protease 38 [Source:HGNC Symbol;Acc:HGNC:29625]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000185894	0	0	0	0	0	0	0	0	0	0	0	0	BPY2C	basic charge Y-linked 2C [Source:HGNC Symbol;Acc:HGNC:18225]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0032399//HECT domain binding	GO:0007283//spermatogenesis;GO:0007338//single fertilization	--
ENSG00000185896	71.737	73.679	65.954	69.086	72.319	62.875	4019	4149	2729	2867	3423	2563	LAMP1	lysosomal associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6499]	Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Transport and catabolism;Transport and catabolism;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome;ko04140//Autophagy - animal;ko04142//Lysosome	K06528;K06528;K06528;K06528	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0035577//azurophil granule membrane;GO:0042383//sarcolemma;GO:0042470//melanosome;GO:0044194//cytolytic granule;GO:0044754//autolysosome;GO:0045335//phagocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0061474//phagolysosome membrane;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0101004//cytolytic granule membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding	GO:0043323//positive regulation of natural killer cell degranulation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0046718//viral entry into host cell;GO:0050821//protein stabilization;GO:0072594//establishment of protein localization to organelle;GO:0090160//Golgi to lysosome transport;GO:0140507//granzyme-mediated programmed cell death signaling pathway;GO:1902513//regulation of organelle transport along microtubule	--
ENSG00000185897	0	0	0	0	0	0	0	0	0	0	0	0	FFAR3	free fatty acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:4499]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0002376//immune system process;GO:0002385//mucosal immune response;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0002879//positive regulation of acute inflammatory response to non-antigenic stimulus;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0014061//regulation of norepinephrine secretion;GO:0032722//positive regulation of chemokine production;GO:0045776//negative regulation of blood pressure;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046885//regulation of hormone biosynthetic process;GO:0071398//cellular response to fatty acid;GO:0090276//regulation of peptide hormone secretion	--
ENSG00000185899	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R60	taste 2 receptor member 60 [Source:HGNC Symbol;Acc:HGNC:20639]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050913//sensory perception of bitter taste	--
ENSG00000185900	3.428	3.742	3.747	3.89	3.996	3.962	595	608	477	449	536	466	POMK	protein O-mannose kinase [Source:HGNC Symbol;Acc:HGNC:26267]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00515//Mannose type O-glycan biosynthesis	K17547;K17547	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0019200//carbohydrate kinase activity"	GO:0001764//neuron migration;GO:0006468//protein phosphorylation;GO:0006493//protein O-linked glycosylation;GO:0007420//brain development;GO:0007611//learning or memory;GO:0016310//phosphorylation;GO:0019233//sensory perception of pain;GO:0046835//carbohydrate phosphorylation;GO:0050905//neuromuscular process	--
ENSG00000185905	0	0	0	0	0	0	0	0	0	0	0	0	C16orf54	chromosome 16 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:26649]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000185909	77.109	76.593	87.588	82.249	75.932	85.715	3154	3149	2646	2492	2624	2551	KLHDC8B	kelch domain containing 8B [Source:HGNC Symbol;Acc:HGNC:28557]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:0110070//cellularization cleavage furrow	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0051301//cell division;GO:0098813//nuclear chromosome segregation;GO:0140014//mitotic nuclear division;GO:1902410//mitotic cytokinetic process	--
ENSG00000185915	0.053	0.079	0.233	0.107	0.094	0.127	4	6	13	6	6	7	KLHL34	kelch like family member 34 [Source:HGNC Symbol;Acc:HGNC:26634]	-	-	-	-	GO:0005615//extracellular space	GO:0005515//protein binding	-	--
ENSG00000185917	2.446	3.145	2.987	2.467	3.667	2.516	125	114	93	75	100	92	SETD4	SET domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1258]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0042800//histone methyltransferase activity (H3-K4 specific)	GO:0006954//inflammatory response;GO:0018023//peptidyl-lysine trimethylation;GO:0018026//peptidyl-lysine monomethylation;GO:0032259//methylation;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034773//histone H4-K20 trimethylation;GO:0044648//histone H3-K4 dimethylation;GO:0050729//positive regulation of inflammatory response;GO:0071863//regulation of cell proliferation in bone marrow;GO:0097692//histone H3-K4 monomethylation	--
ENSG00000185920	4.844	3.025	3.676	6.673	3.391	5.687	486	430	337	365	425	358	PTCH1	patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Cancer: overview;Development and regeneration;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko04024//cAMP signaling pathway;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko05217//Basal cell carcinoma;ko04340//Hedgehog signaling pathway	K06225;K06225;K06225;K06225;K06225;K06225	GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005929//cilium;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody;GO:0030666//endocytic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0060170//ciliary membrane	GO:0005113//patched binding;GO:0005119//smoothened binding;GO:0005515//protein binding;GO:0008158//hedgehog receptor activity;GO:0008201//heparin binding;GO:0015485//cholesterol binding;GO:0030332//cyclin binding;GO:0044877//protein-containing complex binding;GO:0097108//hedgehog family protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001701//in utero embryonic development;GO:0001709//cell fate determination;GO:0001841//neural tube formation;GO:0001843//neural tube closure;GO:0003007//heart morphogenesis;GO:0007165//signal transduction;GO:0007224//smoothened signaling pathway;GO:0007346//regulation of mitotic cell cycle;GO:0007389//pattern specification process;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0008544//epidermis development;GO:0008589//regulation of smoothened signaling pathway;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009887//animal organ morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0009957//epidermal cell fate specification;GO:0010157//response to chlorate;GO:0010875//positive regulation of cholesterol efflux;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0021522//spinal cord motor neuron differentiation;GO:0021532//neural tube patterning;GO:0021904//dorsal/ventral neural tube patterning;GO:0021997//neural plate axis specification;GO:0030326//embryonic limb morphogenesis;GO:0030850//prostate gland development;GO:0030879//mammary gland development;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032880//regulation of protein localization;GO:0035108//limb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0040008//regulation of growth;GO:0040015//negative regulation of multicellular organism growth;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0043616//keratinocyte proliferation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048568//embryonic organ development;GO:0048745//smooth muscle tissue development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051782//negative regulation of cell division;GO:0060037//pharyngeal system development;GO:0060603//mammary gland duct morphogenesis;GO:0060644//mammary gland epithelial cell differentiation;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0061005//cell differentiation involved in kidney development;GO:0061053//somite development;GO:0071397//cellular response to cholesterol;GO:0071679//commissural neuron axon guidance;GO:0072203//cell proliferation involved in metanephros development;GO:0072205//metanephric collecting duct development;GO:0072659//protein localization to plasma membrane;GO:0097421//liver regeneration"	--
ENSG00000185924	0	0.04	0	0	0	0.037	0	3	0	0	0	2	RTN4RL1	reticulon 4 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:21329]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0035374//chondroitin sulfate binding;GO:0038023//signaling receptor activity	GO:0010977//negative regulation of neuron projection development;GO:0022038//corpus callosum development;GO:0031103//axon regeneration;GO:0048681//negative regulation of axon regeneration	--
ENSG00000185926	0	0	0	0	0	0	0	0	0	0	0	0	OR4C46	olfactory receptor family 4 subfamily C member 46 [Source:HGNC Symbol;Acc:HGNC:31271]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000185933	0	0	0	0	0	0.021	0	0	0	0	0	1	CALHM1	calcium homeostasis modulator 1 [Source:HGNC Symbol;Acc:HGNC:23494]	Organismal Systems	Sensory system	ko04742//Taste transduction	K19738	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0015867//ATP transport;GO:0034765//regulation of ion transmembrane transport;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste;GO:0050913//sensory perception of bitter taste;GO:0050916//sensory perception of sweet taste;GO:0050917//sensory perception of umami taste;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization;GO:0070588//calcium ion transmembrane transport	--
ENSG00000185940	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-5	keratin associated protein 5-5 [Source:HGNC Symbol;Acc:HGNC:23601]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000185942	0.55	0.317	0.45	0.824	0.519	0.653	93	46	53	77	79	66	NKAIN3	sodium/potassium transporting ATPase interacting 3 [Source:HGNC Symbol;Acc:HGNC:26829]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0002028//regulation of sodium ion transport	--
ENSG00000185946	3.444	4.035	4.579	4.388	4.424	3.733	145.9	149.45	116	136.52	163.45	120	RNPC3	"RNA binding region (RNP1, RRM) containing 3 [Source:HGNC Symbol;Acc:HGNC:18666]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0030626//U12 snRNA binding;GO:0097157//pre-mRNA intronic binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000185947	2.649	1.889	2.074	1.969	2.109	1.989	170	97	89	57	84	83	ZNF267	zinc finger protein 267 [Source:HGNC Symbol;Acc:HGNC:13060]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000185950	7.064	6.51	6.875	6.759	7.822	8.555	1195	1107	859	847	1118	1053	IRS2	insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Signal transduction;Cancer: overview;Endocrine and metabolic disease;Transport and catabolism;Endocrine system;Signal transduction;Signal transduction;Endocrine system;Endocrine and metabolic disease;Aging;Endocrine system;Aging;Endocrine system;Endocrine and metabolic disease	"ko05010//Alzheimer disease;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko04932//Non-alcoholic fatty liver disease;ko04140//Autophagy - animal;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04931//Insulin resistance;ko04211//Longevity regulating pathway;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04930//Type II diabetes mellitus"	K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187;K07187	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0071889//14-3-3 protein binding	GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002903//negative regulation of B cell apoptotic process;GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0009749//response to glucose;GO:0010748//negative regulation of long-chain fatty acid import across plasma membrane;GO:0010907//positive regulation of glucose metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0030335//positive regulation of cell migration;GO:0030879//mammary gland development;GO:0030890//positive regulation of B cell proliferation;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0032024//positive regulation of insulin secretion;GO:0032869//cellular response to insulin stimulus;GO:0033673//negative regulation of kinase activity;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0055088//lipid homeostasis;GO:0071333//cellular response to glucose stimulus;GO:1901653//cellular response to peptide	--
ENSG00000185955	1.025	1.068	1.387	0.725	0.52	1.408	21	22	21	11	9	21	C7orf61	chromosome 7 open reading frame 61 [Source:HGNC Symbol;Acc:HGNC:22135]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000185958	0	0.045	0	0	0	0	0	2	0	0	0	0	FAM186A	family with sequence similarity 186 member A [Source:HGNC Symbol;Acc:HGNC:26980]	-	-	-	-	-	-	-	--
ENSG00000185960	0	0	0	0	0	0	0	0	0	0	0	0	SHOX	short stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000185962	0	0	0	0	0	0	0	0	0	0	0	0	LCE3A	late cornified envelope 3A [Source:HGNC Symbol;Acc:HGNC:29461]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization;GO:0031640//killing of cells of other organism;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000185963	11.34	10.723	11.845	9.036	9.946	11.528	1186	1121	906	710	865	885	BICD2	BICD cargo adaptor 2 [Source:HGNC Symbol;Acc:HGNC:17208]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005642//annulate lamellae;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0031267//small GTPase binding;GO:0034452//dynactin binding;GO:0051959//dynein light intermediate chain binding;GO:0070840//dynein complex binding	"GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007018//microtubule-based movement;GO:0015031//protein transport;GO:0033365//protein localization to organelle;GO:0034067//protein localization to Golgi apparatus;GO:0051028//mRNA transport;GO:0051642//centrosome localization;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0072393//microtubule anchoring at microtubule organizing center"	--
ENSG00000185966	0	0	0	0	0	0	0	0	0	0	0	0	LCE3E	late cornified envelope 3E [Source:HGNC Symbol;Acc:HGNC:29463]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000185972	0.124	0	0.067	0.033	0.029	0	5	0	2	1	1	0	CCIN	calicin [Source:HGNC Symbol;Acc:HGNC:1568]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0032839//dendrite cytoplasm;GO:0033150//cytoskeletal calyx	GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation	--
ENSG00000185973	6.877	6.206	7.565	5.441	6.078	5.786	398	392	294	227	261	250	TMLHE	"trimethyllysine hydroxylase, epsilon [Source:HGNC Symbol;Acc:HGNC:18308]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K00474;K00474	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0050353//trimethyllysine dioxygenase activity;GO:0051213//dioxygenase activity	GO:0045329//carnitine biosynthetic process;GO:0051354//negative regulation of oxidoreductase activity	--
ENSG00000185974	0	0.034	0.062	0	0.013	0	0	3	4	0	1	0	GRK1	G protein-coupled receptor kinase 1 [Source:HGNC Symbol;Acc:HGNC:10013]	Cellular Processes;Organismal Systems;Organismal Systems	Transport and catabolism;Immune system;Sensory system	ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko04744//Phototransduction	K00909;K00909;K00909	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0042995//cell projection;GO:0097381//photoreceptor disc membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0050254//rhodopsin kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0016056//rhodopsin mediated signaling pathway;GO:0016310//phosphorylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus	--
ENSG00000185982	0	0	0	0	0	0	0	0	0	0	0	0	DEFB128	defensin beta 128 [Source:HGNC Symbol;Acc:HGNC:18106]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000185985	0.306	0.154	0.271	0.153	0.202	0.123	51	27	34	18	29	15	SLITRK2	SLIT and NTRK like family member 2 [Source:HGNC Symbol;Acc:HGNC:13449]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0005515//protein binding	GO:0007409//axonogenesis;GO:0050807//regulation of synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000185988	1.486	1.489	2.635	1.683	1.225	2.444	57	59	70	45	47	68	PLK5	polo like kinase 5 (inactive) [Source:HGNC Symbol;Acc:HGNC:27001]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0000278//mitotic cell cycle;GO:0002357//defense response to tumor cell;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010976//positive regulation of neuron projection development;GO:0030154//cell differentiation;GO:0032465//regulation of cytokinesis;GO:0042981//regulation of apoptotic process;GO:0044819//mitotic G1/S transition checkpoint signaling;GO:0051301//cell division;GO:0071363//cellular response to growth factor stimulus;GO:0090166//Golgi disassembly;GO:2000045//regulation of G1/S transition of mitotic cell cycle	--
ENSG00000185989	6.194	5.672	6.508	5.683	6.286	6.669	540	497	419	367	463	423	RASA3	RAS p21 protein activator 3 [Source:HGNC Symbol;Acc:HGNC:20331]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K12380	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane	GO:0005096//GTPase activator activity;GO:0015278//calcium-release channel activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0043087//regulation of GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0051209//release of sequestered calcium ion into cytosol	--
ENSG00000186001	9.304	12.314	8.305	7.704	10.401	11.035	735	776.01	520	462	569.09	522	LRCH3	leucine rich repeats and calponin homology domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28637]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0032185//septin cytoskeleton organization	--
ENSG00000186007	0.065	0.432	0	0	0.189	0	1	6	0	0	2	0	LEMD1	LEM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18725]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000186009	0.032	0.096	0	0	0.114	0.133	1	3	0	0	3	3	ATP4B	ATPase H+/K+ transporting subunit beta [Source:HGNC Symbol;Acc:HGNC:820]	Metabolism;Metabolism;Organismal Systems;Organismal Systems	Global and overview maps;Energy metabolism;Digestive system;Excretory system	ko01100//Metabolic pathways;ko00190//Oxidative phosphorylation;ko04971//Gastric acid secretion;ko04966//Collecting duct acid secretion	K01543;K01543;K01543;K01543	GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0008900//P-type potassium:proton transporter activity;GO:1901363//heterocyclic compound binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006883//cellular sodium ion homeostasis;GO:0007155//cell adhesion;GO:0010243//response to organonitrogen compound;GO:0030007//cellular potassium ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0036376//sodium ion export across plasma membrane;GO:0045851//pH reduction;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000186010	94.449	94.237	116.866	134.442	92.846	114.567	1022.55	1025.76	934	1080.35	849.16	903.34	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13 [Source:HGNC Symbol;Acc:HGNC:17194]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353;K11353	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respirasome;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006915//apoptotic process;GO:0009060//aerobic respiration;GO:0010952//positive regulation of peptidase activity;GO:0022900//electron transport chain;GO:0030308//negative regulation of cell growth;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0035458//cellular response to interferon-beta;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045039//protein insertion into mitochondrial inner membrane;GO:0045732//positive regulation of protein catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071300//cellular response to retinoic acid;GO:0072593//reactive oxygen species metabolic process;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000186017	2.564	2.002	1.783	1.845	2.038	2.129	279	218	143	149	187	169	ZNF566	zinc finger protein 566 [Source:HGNC Symbol;Acc:HGNC:25919]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186020	2.473	2.604	2.213	2.789	1.837	2.423	264	237	154	179	166	147	ZNF529	zinc finger protein 529 [Source:HGNC Symbol;Acc:HGNC:29328]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186026	0.369	0.693	0.769	0.341	0.394	0.33	33.16	62.68	51.08	22.73	29.93	21.61	ZNF284	zinc finger protein 284 [Source:HGNC Symbol;Acc:HGNC:13078]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186038	0	0	0	0	0	0	0	0	0	0	0	0	HTR3E	5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005]	Organismal Systems;Organismal Systems	Nervous system;Sensory system	ko04726//Serotonergic synapse;ko04742//Taste transduction	K04819;K04819	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:1904602//serotonin-activated cation-selective channel complex	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0022850//serotonin-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000186047	0.251	0.252	0	0.093	0.164	0.127	8	11	0	3	6	4	DLEU7	deleted in lymphocytic leukemia 7 [Source:HGNC Symbol;Acc:HGNC:17567]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000186049	0	0	0	0	0	0	0	0	0	0	0	0	KRT73	keratin 73 [Source:HGNC Symbol;Acc:HGNC:28928]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000186051	0.65	0.144	1.173	0.487	0.171	1.29	9	2	12	5	2	13	TAL2	TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557]	-	-	-	-	GO:0000785//chromatin	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0009791//post-embryonic development;GO:0021794//thalamus development;GO:0030901//midbrain development;GO:0035264//multicellular organism growth	bHLH
ENSG00000186063	22.821	19.633	20.077	15.664	17.884	16.17	1397	1210	915	716	918	726	AIDA	"axin interactor, dorsalization associated [Source:HGNC Symbol;Acc:HGNC:25761]"	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding	GO:0009953//dorsal/ventral pattern formation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0043254//regulation of protein-containing complex assembly;GO:0043508//negative regulation of JUN kinase activity;GO:0046329//negative regulation of JNK cascade;GO:0048264//determination of ventral identity	--
ENSG00000186073	5.632	5.073	4.913	3.645	4.232	4.774	319	287	192	159	205	202	CDIN1	CDAN1 interacting nuclease 1 [Source:HGNC Symbol;Acc:HGNC:26929]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0030218//erythrocyte differentiation	--
ENSG00000186074	0	0	0	0	0	0	0	0	0	0	0	0	CD300LF	CD300 molecule like family member f [Source:HGNC Symbol;Acc:HGNC:29883]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001786//phosphatidylserine binding;GO:0004888//transmembrane signaling receptor activity;GO:0005136//interleukin-4 receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0097001//ceramide binding	GO:0002376//immune system process;GO:0033004//negative regulation of mast cell activation;GO:0034125//negative regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0035772//interleukin-13-mediated signaling pathway;GO:1902216//positive regulation of interleukin-4-mediated signaling pathway;GO:2000426//negative regulation of apoptotic cell clearance;GO:2000427//positive regulation of apoptotic cell clearance	--
ENSG00000186075	0	0	0	0	0	0	0	0	0	0	0	0	ZPBP2	zona pellucida binding protein 2 [Source:HGNC Symbol;Acc:HGNC:20678]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0002199//zona pellucida receptor complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0044297//cell body	-	GO:0001675//acrosome assembly;GO:0002638//negative regulation of immunoglobulin production;GO:0006665//sphingolipid metabolic process;GO:0007339//binding of sperm to zona pellucida;GO:0032922//circadian regulation of gene expression;GO:0046466//membrane lipid catabolic process	--
ENSG00000186081	0.086	0.226	0.396	0.116	0.025	0.118	4	6	8	4	1	4	KRT5	keratin 5 [Source:HGNC Symbol;Acc:HGNC:6442]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0097110//scaffold protein binding	GO:0007010//cytoskeleton organization;GO:0008544//epidermis development;GO:0070268//cornification	--
ENSG00000186086	0.014	0.051	0	0	0.026	0	1	2	0	0	1	0	NBPF6	NBPF member 6 [Source:HGNC Symbol;Acc:HGNC:31988]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000186088	0.347	0.33	0.811	0.692	0.446	0.6	23	22	31	34	25	29	GSAP	gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network	GO:0001540//amyloid-beta binding;GO:0005515//protein binding	GO:0030162//regulation of proteolysis;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000186090	0	0	0	0	0	0	0	0	0	0	0	0	HTR3D	5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004]	Organismal Systems;Organismal Systems	Nervous system;Sensory system	ko04726//Serotonergic synapse;ko04742//Taste transduction	K04819;K04819	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse;GO:1904602//serotonin-activated cation-selective channel complex	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0022850//serotonin-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007210//serotonin receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0098662//inorganic cation transmembrane transport	--
ENSG00000186092	0	0	0	0	0	0	0	0	0	0	0	0	OR4F5	olfactory receptor family 4 subfamily F member 5 [Source:HGNC Symbol;Acc:HGNC:14825]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186094	0.416	0.42	0.32	0.396	0.143	0.2	20	16	11	19	6	9	AGBL4	AGBL carboxypeptidase 4 [Source:HGNC Symbol;Acc:HGNC:25892]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K23439	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030424//axon;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:1904115//axon cytoplasm	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0008285//negative regulation of cell population proliferation;GO:0021954//central nervous system neuron development;GO:0035608//protein deglutamylation;GO:0035609//C-terminal protein deglutamylation;GO:0035610//protein side chain deglutamylation;GO:0051607//defense response to virus;GO:0098930//axonal transport;GO:0098957//anterograde axonal transport of mitochondrion;GO:0098958//retrograde axonal transport of mitochondrion;GO:0120222//regulation of blastocyst development;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process	--
ENSG00000186103	0	0	0	0	0	0	0	0	0	0	0	0	ARGFX	arginine-fifty homeobox [Source:HGNC Symbol;Acc:HGNC:30146]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000186104	2.729	3.58	3.643	2.684	3.966	3.713	112	139	104	81	114	102	CYP2R1	cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K07419;K07419	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:1902271//D3 vitamins binding"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0042359//vitamin D metabolic process;GO:0042368//vitamin D biosynthetic process	--
ENSG00000186105	0	0	0	0	0	0.031	0	0	0	0	0	1	LRRC70	leucine rich repeat containing 70 [Source:HGNC Symbol;Acc:HGNC:35155]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0060760//positive regulation of response to cytokine stimulus	--
ENSG00000186106	11.179	11.479	12.756	10.893	12.229	13.717	523	486	433	399	453	478	ANKRD46	ankyrin repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:27229]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000186111	54.337	56.387	50.494	58.826	61.572	52.202	5109	5345	3532	4106	4894	3481	PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [Source:HGNC Symbol;Acc:HGNC:8996]	Metabolism;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Transport and catabolism;Cell motility;Signal transduction;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Cancer: overview;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko04072//Phospholipase D signaling pathway;ko05135//Yersinia infection;ko04510//Focal adhesion;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889;K00889	GO:0001891//phagocytic cup;GO:0001931//uropod;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0010008//endosome membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0098793//presynapse	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016740//transferase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity"	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006887//exocytosis;GO:0006897//endocytosis;GO:0006909//phagocytosis;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0016079//synaptic vesicle exocytosis;GO:0016310//phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030593//neutrophil chemotaxis;GO:0034333//adherens junction assembly;GO:0046488//phosphatidylinositol metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048488//synaptic vesicle endocytosis;GO:0061024//membrane organization;GO:0072583//clathrin-dependent endocytosis;GO:0098609//cell-cell adhesion	--
ENSG00000186113	0	0	0	0	0	0	0	0	0	0	0	0	OR5D14	olfactory receptor family 5 subfamily D member 14 [Source:HGNC Symbol;Acc:HGNC:15281]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186115	0	0	0	0	0	0	0	0	0	0	0	0	CYP4F2	cytochrome P450 family 4 subfamily F member 2 [Source:HGNC Symbol;Acc:HGNC:2645]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K17726;K17726	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0018685//alkane 1-monooxygenase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0052869//arachidonic acid omega-hydroxylase activity;GO:0052871//alpha-tocopherol omega-hydroxylase activity;GO:0052872//tocotrienol omega-hydroxylase activity;GO:0070330//aromatase activity;GO:0097258//20-hydroxy-leukotriene B4 omega oxidase activity;GO:0097259//20-aldehyde-leukotriene B4 20-monooxygenase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity;GO:0102207//docosanoate omega-hydroxylase activity"	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0003091//renal water homeostasis;GO:0003095//pressure natriuresis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006691//leukotriene metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007596//blood coagulation;GO:0008217//regulation of blood pressure;GO:0010430//fatty acid omega-oxidation;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0032304//negative regulation of icosanoid secretion;GO:0032305//positive regulation of icosanoid secretion;GO:0036101//leukotriene B4 catabolic process;GO:0042360//vitamin E metabolic process;GO:0042361//menaquinone catabolic process;GO:0042376//phylloquinone catabolic process;GO:0042377//vitamin K catabolic process;GO:0055078//sodium ion homeostasis;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000186118	0	0	0.065	0	0	0	0	0	1	0	0	0	TEX38	testis expressed 38 [Source:HGNC Symbol;Acc:HGNC:29589]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186119	0	0	0	0	0	0	0	0	0	0	0	0	OR5D18	olfactory receptor family 5 subfamily D member 18 [Source:HGNC Symbol;Acc:HGNC:15285]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186130	4.164	3.042	2.787	2.938	2.255	3.783	354	260	175	185	162	234	ZBTB6	zinc finger and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:16764]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000186132	2.503	4.597	3.882	3.991	3.141	2.999	36	66	41	42	39	31	C2orf76	chromosome 2 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:27017]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186136	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R42	taste 2 receptor member 42 [Source:HGNC Symbol;Acc:HGNC:18888]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000186141	7.033	7.141	6.119	5.627	5.715	6.295	356	339	234	210	238	224	POLR3C	RNA polymerase III subunit C [Source:HGNC Symbol;Acc:HGNC:30076]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03023;K03023	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006351//transcription, DNA-templated;GO:0006359//regulation of transcription by RNA polymerase III;GO:0032728//positive regulation of interferon-beta production;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus"	--
ENSG00000186143	0	0	0	0	0	0	0	0	0	0	0	0	PRR30	proline rich 30 [Source:HGNC Symbol;Acc:HGNC:28677]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186146	0	0	0	0	0	0	0	0	0	0	0	0	DEFB131A	defensin beta 131A [Source:HGNC Symbol;Acc:HGNC:18108]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000186150	0	0	0	0	0	0	0	0	0	0	0	0	UBL4B	ubiquitin like 4B [Source:HGNC Symbol;Acc:HGNC:32309]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000186153	7.693	6.861	6.438	6.966	6.187	7.883	267	288	184	175	205	202	WWOX	WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0090575//RNA polymerase II transcription regulator complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0042802//identical protein binding	GO:0001649//osteoblast differentiation;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048705//skeletal system morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0097191//extrinsic apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000186160	0	0	0	0	0	0	0	0	0	0	0	0	CYP4Z1	cytochrome P450 family 4 subfamily Z member 1 [Source:HGNC Symbol;Acc:HGNC:20583]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008404//arachidonic acid 14,15-epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0052722//fatty acid in-chain hydroxylase activity;GO:0070330//aromatase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0048252//lauric acid metabolic process	--
ENSG00000186166	2.238	2.78	2.494	2.672	2.626	3.757	58	72	48	51	58	70	CENATAC	centrosomal AT-AC splicing factor [Source:HGNC Symbol;Acc:HGNC:30460]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0010826//negative regulation of centrosome duplication;GO:0042176//regulation of protein catabolic process	--
ENSG00000186174	15.211	15.396	15.031	15.298	16.479	17.425	2390	2436	1741	1775	2156	1984	BCL9L	BCL9 like [Source:HGNC Symbol;Acc:HGNC:23688]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:1990907//beta-catenin-TCF complex	GO:0003713//transcription coactivator activity;GO:0008013//beta-catenin binding	"GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0022604//regulation of cell morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0035019//somatic stem cell population maintenance;GO:0035914//skeletal muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060070//canonical Wnt signaling pathway"	--
ENSG00000186184	52.775	44.798	53.479	50.709	41.927	54.035	1169	1019	870	860	772	873	POLR1D	RNA polymerase I and III subunit D [Source:HGNC Symbol;Acc:HGNC:20422]	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03020;K03020	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005736//RNA polymerase I complex;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated"	--
ENSG00000186185	0.101	0.058	0.124	0.094	0.108	0.135	8	4	8	6	8	7	KIF18B	kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102]	-	-	-	-	GO:0000235//astral microtubule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016604//nuclear body;GO:0035371//microtubule plus-end;GO:0061673//mitotic spindle astral microtubule;GO:1990023//mitotic spindle midzone;GO:1990752//microtubule end	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity;GO:0019894//kinesin binding	GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0007049//cell cycle;GO:0051301//cell division;GO:0051302//regulation of cell division	--
ENSG00000186187	9.511	8.303	12.378	12.31	13.445	12.1	507	436	453	423	470	448	ZNRF1	zinc and ring finger 1 [Source:HGNC Symbol;Acc:HGNC:18452]	-	-	-	-	GO:0005764//lysosome;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000186188	0	0	0	0	0	0	0	0	0	0	0	0	FFAR4	free fatty acid receptor 4 [Source:HGNC Symbol;Acc:HGNC:19061]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008527//taste receptor activity;GO:1990763//arrestin family protein binding	GO:0001818//negative regulation of cytokine production;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010827//regulation of glucose transmembrane transport;GO:0030154//cell differentiation;GO:0032691//negative regulation of interleukin-1 beta production;GO:0036321//ghrelin secretion;GO:0043066//negative regulation of apoptotic process;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0045444//fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0046879//hormone secretion;GO:0050728//negative regulation of inflammatory response;GO:0050872//white fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0070094//positive regulation of glucagon secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090275//negative regulation of somatostatin secretion;GO:0090336//positive regulation of brown fat cell differentiation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000186190	0	0	0	0	0	0	0	0	0	0	0	0	BPIFB3	BPI fold containing family B member 3 [Source:HGNC Symbol;Acc:HGNC:16178]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0045087//innate immune response	--
ENSG00000186191	1.914	1.617	1.17	0.083	0.317	0.368	93	79	42	3	13	13	BPIFB4	BPI fold containing family B member 4 [Source:HGNC Symbol;Acc:HGNC:16179]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0008289//lipid binding	-	--
ENSG00000186193	0.076	0.038	0.034	0.119	0.135	0.017	6	3	2	7	9	1	SAPCD2	suppressor APC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28055]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0043296//apical junction complex;GO:0045179//apical cortex	GO:0005515//protein binding	GO:0000132//establishment of mitotic spindle orientation;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0051301//cell division;GO:0090175//regulation of establishment of planar polarity;GO:0098725//symmetric cell division;GO:1904777//negative regulation of protein localization to cell cortex	--
ENSG00000186197	0.174	0.185	0.14	0.163	0.163	0.236	11	12	6	7	8	10	EDARADD	EDAR associated death domain [Source:HGNC Symbol;Acc:HGNC:14341]	Environmental Information Processing	Signal transduction	ko04064//NF-kappa B signaling pathway	K23324	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0030154//cell differentiation	--
ENSG00000186198	0.052	0.208	0	0	0	0	1	4	0	0	0	0	SLC51B	solute carrier family 51 subunit beta [Source:HGNC Symbol;Acc:HGNC:29956]	Organismal Systems	Digestive system	ko04976//Bile secretion	K14361	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0015125//bile acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0046982//protein heterodimerization activity	GO:0015721//bile acid and bile salt transport;GO:0031647//regulation of protein stability;GO:0032782//bile acid secretion;GO:0055085//transmembrane transport;GO:0060050//positive regulation of protein glycosylation;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0071702//organic substance transport;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000186204	0	0	0	0	0	0	0	0	0	0	0	0	CYP4F12	cytochrome P450 family 4 subfamily F member 12 [Source:HGNC Symbol;Acc:HGNC:18857]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0018685//alkane 1-monooxygenase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0070330//aromatase activity"	GO:0000038//very long-chain fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0003091//renal water homeostasis;GO:0003095//pressure natriuresis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0036101//leukotriene B4 catabolic process;GO:0042360//vitamin E metabolic process;GO:0042361//menaquinone catabolic process;GO:0042376//phylloquinone catabolic process;GO:0055078//sodium ion homeostasis	--
ENSG00000186205	5.933	6.69	5.128	7.618	7.036	5.929	265	291	186.8	233.12	259	196	MTARC1	mitochondrial amidoxime reducing component 1 [Source:HGNC Symbol;Acc:HGNC:26189]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1903958//nitric-oxide synthase complex	"GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008940//nitrate reductase activity;GO:0016491//oxidoreductase activity;GO:0016661//oxidoreductase activity, acting on other nitrogenous compounds as donors;GO:0030151//molybdenum ion binding;GO:0030170//pyridoxal phosphate binding;GO:0043546//molybdopterin cofactor binding;GO:0046872//metal ion binding;GO:0050421//nitrite reductase (NO-forming) activity;GO:0098809//nitrite reductase activity"	GO:0006809//nitric oxide biosynthetic process;GO:0042126//nitrate metabolic process;GO:0051410//detoxification of nitrogen compound;GO:0070458//cellular detoxification of nitrogen compound	--
ENSG00000186207	0.056	0	0	0	0	0	1	0	0	0	0	0	LCE5A	late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000186212	0.241	0.36	0.311	0.212	0.3	0.465	20	30	19	13	21	28	SOWAHB	sosondowah ankyrin repeat domain family member B [Source:HGNC Symbol;Acc:HGNC:32958]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186222	6.338	6.82	6.655	7.857	5.779	8.044	196	212	152	180	151	181	BLOC1S4	biogenesis of lysosomal organelles complex 1 subunit 4 [Source:HGNC Symbol;Acc:HGNC:24206]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031083//BLOC-1 complex;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0008089//anterograde axonal transport;GO:0031175//neuron projection development;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0050885//neuromuscular process controlling balance;GO:0070527//platelet aggregation	--
ENSG00000186226	0.121	0	0	0	0.099	0.115	3	0	0	0	1	1	LCE1E	late cornified envelope 1E [Source:HGNC Symbol;Acc:HGNC:29466]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000186230	1.361	1.049	0.869	0.681	0.705	1.59	65	92	56	44	52	62	ZNF749	zinc finger protein 749 [Source:HGNC Symbol;Acc:HGNC:32783]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186231	0.124	0.04	0.133	0.141	0.155	0.179	8	3	3	8	9	10	KLHL32	kelch like family member 32 [Source:HGNC Symbol;Acc:HGNC:21221]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186260	7.492	7.344	5.345	4.969	5.691	6.508	1150	940	666	446	650	623	MRTFB	myocardin related transcription factor B [Source:HGNC Symbol;Acc:HGNC:29819]	-	-	-	-	GO:0005634//nucleus	GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0043086//negative regulation of catalytic activity;GO:0045844//positive regulation of striated muscle tissue development;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051145//smooth muscle cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II	--
ENSG00000186265	0.015	0	0	0.042	0	0	1	0	0	2	0	0	BTLA	B and T lymphocyte associated [Source:HGNC Symbol;Acc:HGNC:21087]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002768//immune response-regulating cell surface receptor signaling pathway	--
ENSG00000186272	1.971	1.811	1.693	1.948	1.878	2.597	110	101	69	81	85	106	ZNF17	zinc finger protein 17 [Source:HGNC Symbol;Acc:HGNC:12958]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186280	1.009	0.894	0.796	0.652	0.673	0.943	59	55	36	29	32	42	KDM4D	lysine demethylase 4D [Source:HGNC Symbol;Acc:HGNC:25498]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0035861//site of double-strand break;GO:0072562//blood microparticle	GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0031490//chromatin DNA binding;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0140684//histone H3-tri/dimethyl-lysine-9 demethylase activity	GO:0000724//double-strand break repair via homologous recombination;GO:0001932//regulation of protein phosphorylation;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0033169//histone H3-K9 demethylation;GO:0035563//positive regulation of chromatin binding;GO:0071479//cellular response to ionizing radiation;GO:1900113//negative regulation of histone H3-K9 trimethylation;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000186281	0.159	0.315	0.132	0.221	0.069	0.048	9	18	5	2	3	2	GPAT2	"glycerol-3-phosphate acyltransferase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:27168]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K00629;K00629;K00629	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0102420//sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	GO:0006072//glycerol-3-phosphate metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:1990511//piRNA biosynthetic process	--
ENSG00000186283	22.841	23.725	19.602	19.953	20.902	22.957	872	842	559	518	627	510	TOR3A	torsin family 3 member A [Source:HGNC Symbol;Acc:HGNC:11997]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000186288	0	0	0	0.058	0.026	0.03	0	0	0	2	1	1	PABPC1L2A	poly(A) binding protein cytoplasmic 1 like 2A [Source:HGNC Symbol;Acc:HGNC:27989]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000186297	2.266	2.176	1.761	1.428	1.766	1.298	98	95	58	56	79	50	GABRA5	gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Sensory system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko05033//Nicotine addiction	K05175;K05175;K05175;K05175;K05175;K05175	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032590//dendrite membrane;GO:0032809//neuronal cell body membrane;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0044297//cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098794//postsynapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005215//transporter activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008503//benzodiazepine receptor activity;GO:0022851//GABA-gated chloride ion channel activity;GO:0030594//neurotransmitter receptor activity;GO:0038023//signaling receptor activity;GO:0050811//GABA receptor binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	"GO:0001662//behavioral fear response;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0007605//sensory perception of sound;GO:0008306//associative learning;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043523//regulation of neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0048666//neuron development;GO:0050877//nervous system process;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060119//inner ear receptor cell development;GO:0060384//innervation;GO:0090102//cochlea development;GO:1902476//chloride transmembrane transport"	--
ENSG00000186298	67.418	53.972	56.53	49.315	62.216	58.488	3010	2747	1972	1888	2287	2102	PPP1CC	protein phosphatase 1 catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:9283]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Genetic Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Cell motility;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Substance dependence;Signal transduction;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine and metabolic disease;Translation;Sensory system;Substance dependence;Nervous system	ko05168//Herpes simplex virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04931//Insulin resistance;ko03015//mRNA surveillance pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269	"GO:0000164//protein phosphatase type 1 complex;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016607//nuclear speck;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0032991//protein-containing complex;GO:0043197//dendritic spine;GO:0072357//PTW/PP1 phosphatase complex;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0110165//cellular anatomical entity"	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0008022//protein C-terminus binding;GO:0008157//protein phosphatase 1 binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0030182//neuron differentiation;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0046822//regulation of nucleocytoplasmic transport;GO:0048511//rhythmic process;GO:0051301//cell division;GO:0060252//positive regulation of glial cell proliferation	--
ENSG00000186300	3.076	2.398	2.704	2.365	2.804	3.806	274	236	211	166	189	176	ZNF555	zinc finger protein 555 [Source:HGNC Symbol;Acc:HGNC:28382]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186306	0	0	0	0	0	0	0	0	0	0	0	0	OR10T2	olfactory receptor family 10 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:14816]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186310	11.812	10.158	9.882	10.885	9.694	9.68	649	561	401	443	450	387	NAP1L3	nucleosome assembly protein 1 like 3 [Source:HGNC Symbol;Acc:HGNC:7639]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly	--
ENSG00000186314	3.852	3.263	2.712	3.041	2.733	3.826	247	259	168	132	174	176	PRELID2	PRELI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28306]	-	-	-	-	GO:0005758//mitochondrial intermembrane space	GO:1990050//phosphatidic acid transfer activity	GO:0015914//phospholipid transport;GO:0120009//intermembrane lipid transfer	--
ENSG00000186318	29.222	31.577	28.377	24.583	27.608	25.831	3204.6	3481.89	2303.59	2011.92	2500.33	2021.95	BACE1	beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933]	Human Diseases	Neurodegenerative disease	ko05010//Alzheimer disease	K04521	GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005771//multivesicular body;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045121//membrane raft;GO:0055037//recycling endosome;GO:0070931//Golgi-associated vesicle lumen;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098793//presynapse	GO:0001540//amyloid-beta binding;GO:0004175//endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008798//beta-aspartyl-peptidase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0009314//response to radiation;GO:0010288//response to lead ion;GO:0016485//protein processing;GO:0034205//amyloid-beta formation;GO:0042987//amyloid precursor protein catabolic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0050435//amyloid-beta metabolic process;GO:0050804//modulation of chemical synaptic transmission;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0060134//prepulse inhibition;GO:0071280//cellular response to copper ion;GO:0071287//cellular response to manganese ion;GO:1904646//cellular response to amyloid-beta;GO:1990000//amyloid fibril formation;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000186326	1.023	0.782	1.49	2.415	1.279	2.674	52.04	40	56	91	55	99	RGS9BP	regulator of G protein signaling 9 binding protein [Source:HGNC Symbol;Acc:HGNC:30304]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	-	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0009968//negative regulation of signal transduction;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception	--
ENSG00000186329	0.026	0	0.035	0	0	0	1	0	1	0	0	0	TMEM212	transmembrane protein 212 [Source:HGNC Symbol;Acc:HGNC:34295]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186334	0	0	0	0	0	0	0	0	0	0	0	0	SLC36A3	solute carrier family 36 member 3 [Source:HGNC Symbol;Acc:HGNC:19659]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14209	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005280//amino acid:proton symporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0015808//L-alanine transport;GO:0015816//glycine transport;GO:0035524//proline transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000186335	0.066	0.056	0.096	0.126	0.05	0.467	2	4	3	4	3	5	SLC36A2	solute carrier family 36 member 2 [Source:HGNC Symbol;Acc:HGNC:18762]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K14209	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005280//amino acid:proton symporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0015808//L-alanine transport;GO:0015816//glycine transport;GO:0015824//proline transport;GO:0035524//proline transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000186340	15.175	14.692	2.837	5.217	8.796	4.968	1748	1696	249	457	877	426	THBS2	thrombospondin 2 [Source:HGNC Symbol;Acc:HGNC:11786]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Transport and catabolism;Cellular community - eukaryotes;Signaling molecules and interaction;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko04510//Focal adhesion;ko04512//ECM-receptor interaction;ko05144//Malaria	K04659;K04659;K04659;K04659;K04659;K04659	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0031012//extracellular matrix;GO:0031091//platelet alpha granule;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0007155//cell adhesion;GO:0016525//negative regulation of angiogenesis;GO:0051965//positive regulation of synapse assembly	--
ENSG00000186350	16.779	16.293	17.649	15.187	15.037	15.557	1927	1876	1497	1292	1459	1300	RXRA	retinoid X receptor alpha [Source:HGNC Symbol;Acc:HGNC:10477]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Cancer: overview;Cardiovascular disease;Cancer: overview;Endocrine and metabolic disease;Infectious disease: viral;Cancer: specific types;Endocrine system;Immune system;Endocrine system;Cancer: specific types;Digestive system;Endocrine system;Cancer: specific types;Endocrine system;Cancer: specific types	"ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05202//Transcriptional misregulation in cancer;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko05226//Gastric cancer;ko04919//Thyroid hormone signaling pathway;ko04659//Th17 cell differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko05222//Small cell lung cancer;ko04976//Bile secretion;ko03320//PPAR signaling pathway;ko05223//Non-small cell lung cancer;ko04920//Adipocytokine signaling pathway;ko05216//Thyroid cancer"	K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524;K08524	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043235//receptor complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001221//transcription coregulator binding;GO:0001972//retinoic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016922//nuclear receptor binding;GO:0019899//enzyme binding;GO:0042277//peptide binding;GO:0042802//identical protein binding;GO:0042809//vitamin D receptor binding;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding;GO:0050692//DNA binding domain binding;GO:0050693//LBD domain binding;GO:0070644//vitamin D response element binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002157//positive regulation of thyroid hormone mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008203//cholesterol metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0010875//positive regulation of cholesterol efflux;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0032411//positive regulation of transporter activity;GO:0032526//response to retinoic acid;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043401//steroid hormone mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048856//anatomical structure development;GO:0070564//positive regulation of vitamin D receptor signaling pathway"	RXR-like
ENSG00000186352	6.381	7.202	4.577	6.973	5.035	5.268	103.39	117.34	54.59	82.89	67.3	62.33	ANKRD37	ankyrin repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:29593]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000186364	1.231	1.323	1.176	1.706	1.875	1.063	37.6	40.63	26.54	38.61	48.41	23.63	NUDT17	nudix hydrolase 17 [Source:HGNC Symbol;Acc:HGNC:26618]	-	-	-	-	GO:0005777//peroxisome	GO:0016787//hydrolase activity;GO:0035529//NADH pyrophosphatase activity;GO:0046872//metal ion binding	GO:0006734//NADH metabolic process;GO:0006742//NADP catabolic process;GO:0019677//NAD catabolic process	--
ENSG00000186367	0	0	0	0	0	0	0	0	0	0	0	0	MINAR2	membrane integral NOTCH2 associated receptor 2 [Source:HGNC Symbol;Acc:HGNC:33914]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186376	2.043	1.462	1.435	0.918	1.232	1.417	197	157	98	73	114	104	ZNF75D	zinc finger protein 75D [Source:HGNC Symbol;Acc:HGNC:13145]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186377	0	0	0	0	0	0.029	0	0	0	0	0	1	CYP4X1	cytochrome P450 family 4 subfamily X member 1 [Source:HGNC Symbol;Acc:HGNC:20244]	Organismal Systems	Nervous system	ko04726//Serotonergic synapse	K07428	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0062189//anandamide 14,15 epoxidase activity"	GO:0006629//lipid metabolic process	--
ENSG00000186393	0	0	0	0	0	0	0	0	0	0	0	0	KRT26	keratin 26 [Source:HGNC Symbol;Acc:HGNC:30840]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	-	--
ENSG00000186395	2.428	1.967	2.802	2.671	2.634	3.523	108	88	92	88	99	114	KRT10	keratin 10 [Source:HGNC Symbol;Acc:HGNC:6413]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0009986//cell surface;GO:0016020//membrane;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis;GO:0046982//protein heterodimerization activity	GO:0002009//morphogenesis of an epithelium;GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0030855//epithelial cell differentiation;GO:0045684//positive regulation of epidermis development;GO:0051290//protein heterotetramerization	--
ENSG00000186399	0.358	0.388	0.195	0.531	0.52	0.337	38.38	41.79	15.46	42.18	47.14	26.3	GOLGA8R	golgin A8 family member R [Source:HGNC Symbol;Acc:HGNC:44407]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000186407	0	0	0	0	0	0	0	0	0	0	0	0	CD300E	CD300e molecule [Source:HGNC Symbol;Acc:HGNC:28874]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0002376//immune system process	--
ENSG00000186409	1.276	0.978	0.924	0.945	0.566	0.547	102	69	52	33	31	31	CCDC30	coiled-coil domain containing 30 [Source:HGNC Symbol;Acc:HGNC:26103]	-	-	-	-	-	-	-	--
ENSG00000186416	4.316	4.534	4.005	3.487	3.499	3.851	297	300	191	160	193	182	NKRF	NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0001671//ATPase activator activity;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding"	"GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	Others
ENSG00000186417	0.206	0.156	0.086	0.281	0.242	0.142	14	11	5	9	11	5	GLDN	gliomedin [Source:HGNC Symbol;Acc:HGNC:29514]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection	GO:0086080//protein binding involved in heterotypic cell-cell adhesion	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0032528//microvillus organization;GO:0034113//heterotypic cell-cell adhesion;GO:0045162//clustering of voltage-gated sodium channels	--
ENSG00000186431	0	0	0	0	0	0	0	0	0	0	0	0	FCAR	Fc fragment of IgA receptor [Source:HGNC Symbol;Acc:HGNC:3608]	Cellular Processes;Human Diseases	Transport and catabolism;Infectious disease: bacterial	ko04145//Phagosome;ko05150//Staphylococcus aureus infection	K06513;K06513	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0019766//IgA receptor activity;GO:0019862//IgA binding	GO:0002446//neutrophil mediated immunity;GO:0006955//immune response;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0035457//cellular response to interferon-alpha;GO:0038093//Fc receptor signaling pathway;GO:0042119//neutrophil activation;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:1903209//positive regulation of oxidative stress-induced cell death	--
ENSG00000186432	21.222	16.982	16.85	13.704	15.208	17.666	1754	1386	1032	782	1019	975	KPNA4	karyopherin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6397]	Human Diseases;Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Cancer: overview;Translation	ko05132//Salmonella infection;ko05207//Chemical carcinogenesis - receptor activation;ko03013//Nucleocytoplasmic transport	K23583;K23583;K23583	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0042564//NLS-dependent protein nuclear import complex	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0015031//protein transport;GO:0016032//viral process	--
ENSG00000186439	0	0	0	0	0	0	0	0	0	0	0	0	TRDN	triadin [Source:HGNC Symbol;Acc:HGNC:12261]	Environmental Information Processing;Organismal Systems	Signal transduction;Circulatory system	ko04020//Calcium signaling pathway;ko04260//Cardiac muscle contraction	K23449;K23449	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030314//junctional membrane complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0044325//transmembrane transporter binding	GO:0006874//cellular calcium ion homeostasis;GO:0006936//muscle contraction;GO:0009617//response to bacterium;GO:0010649//regulation of cell communication by electrical coupling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0031122//cytoplasmic microtubule organization;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0060047//heart contraction;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0090158//endoplasmic reticulum membrane organization;GO:1901846//positive regulation of cell communication by electrical coupling involved in cardiac conduction	--
ENSG00000186440	0	0	0	0	0	0	0	0	0	0	0	0	OR6P1	olfactory receptor family 6 subfamily P member 1 [Source:HGNC Symbol;Acc:HGNC:15036]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186442	0	0	0	0	0	0	0	0	0	0	0	0	KRT3	keratin 3 [Source:HGNC Symbol;Acc:HGNC:6440]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000186446	1.101	0.764	0.906	0.592	0.538	0.426	74	53	43	30	31	21	ZNF501	zinc finger protein 501 [Source:HGNC Symbol;Acc:HGNC:23717]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007030//Golgi organization	zf-C2H2
ENSG00000186448	7	4.733	4.194	3.869	4.481	5.594	658	467	302	243	341	323	ZNF197	zinc finger protein 197 [Source:HGNC Symbol;Acc:HGNC:12988]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186451	0.198	0.482	0.417	0.178	0.339	0.121	9	22	14	6	13	4	SPATA12	spermatogenesis associated 12 [Source:HGNC Symbol;Acc:HGNC:23221]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186452	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS12	transmembrane serine protease 12 [Source:HGNC Symbol;Acc:HGNC:28779]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007339//binding of sperm to zona pellucida;GO:0016485//protein processing	--
ENSG00000186453	0.159	0.131	0.072	0.25	0.313	0.218	6	5	2	7	10	6	FAM228A	family with sequence similarity 228 member A [Source:HGNC Symbol;Acc:HGNC:34418]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000186458	0	0	0	0	0	0	0	0	0	0	0	0	DEFB132	defensin beta 132 [Source:HGNC Symbol;Acc:HGNC:33806]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0061827//sperm head	GO:0005515//protein binding	GO:0006952//defense response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000186462	5.061	5.862	5.753	4.665	5.588	5.684	268	312	225	183	250	219	NAP1L2	nucleosome assembly protein 1 like 2 [Source:HGNC Symbol;Acc:HGNC:7638]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0035066//positive regulation of histone acetylation;GO:0045666//positive regulation of neuron differentiation;GO:0071442//positive regulation of histone H3-K14 acetylation;GO:2000035//regulation of stem cell division;GO:2000617//positive regulation of histone H3-K9 acetylation	--
ENSG00000186468	549.608	569.775	578.48	625.108	494.806	524.182	7893	8044	6019	6124	5892	5322	RPS23	ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02973;K02973	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0042788//polysomal ribosome;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0034063//stress granule assembly;GO:1990145//maintenance of translational fidelity	--
ENSG00000186469	0.273	0.148	0.21	0.217	0.175	0.097	10	11	11	4	6	5	GNG2	G protein subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4404]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826;K07826	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0008283//cell population proliferation;GO:0071380//cellular response to prostaglandin E stimulus;GO:0071870//cellular response to catecholamine stimulus	--
ENSG00000186470	4.212	3.776	6.821	4.92	5.448	4.125	288	264.24	276	275.55	304	198	BTN3A2	butyrophilin subfamily 3 member A2 [Source:HGNC Symbol;Acc:HGNC:1139]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0032729//positive regulation of interferon-gamma production;GO:0050852//T cell receptor signaling pathway	--
ENSG00000186471	0	0.104	0	0.212	0.186	0	0	2	0	3	3	0	AKAP14	A-kinase anchoring protein 14 [Source:HGNC Symbol;Acc:HGNC:24061]	-	-	-	-	GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0005952//cAMP-dependent protein kinase complex	GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding	GO:0008150//biological_process	--
ENSG00000186472	1.27	0.671	1.728	0.986	1.43	1.14	267	158	120	125	176	153	PCLO	piccolo presynaptic cytomatrix protein [Source:HGNC Symbol;Acc:HGNC:13406]	Organismal Systems	Endocrine system	ko04911//Insulin secretion	K16882	GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone;GO:0070062//extracellular exosome;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding;GO:0098882//structural constituent of presynaptic active zone	GO:0007010//cytoskeleton organization;GO:0007416//synapse assembly;GO:0016079//synaptic vesicle exocytosis;GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0035418//protein localization to synapse;GO:0048790//maintenance of presynaptic active zone structure;GO:0097091//synaptic vesicle clustering;GO:0099526//presynapse to nucleus signaling pathway;GO:1904071//presynaptic active zone assembly	--
ENSG00000186474	0	0	0	0	0	0	0	0	0	0	0	0	KLK12	kallikrein related peptidase 12 [Source:HGNC Symbol;Acc:HGNC:6360]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000186479	3.737	2.037	1.76	2.764	3.103	3.052	345	189	120	189	242	205	RGS7BP	regulator of G protein signaling 7 binding protein [Source:HGNC Symbol;Acc:HGNC:23271]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0043005//neuron projection;GO:0043198//dendritic shaft;GO:0043204//perikaryon;GO:0044327//dendritic spine head;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099026//anchored component of presynaptic membrane;GO:0099031//anchored component of postsynaptic density membrane	-	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0060078//regulation of postsynaptic membrane potential	--
ENSG00000186480	44.744	42.692	41.385	51.055	46.786	62.095	2441	2361	1765	2078	2139	2498	INSIG1	insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032937//SREBP-SCAP-Insig complex	GO:0005515//protein binding;GO:0008142//oxysterol binding;GO:0008289//lipid binding	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006991//response to sterol depletion;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0010894//negative regulation of steroid biosynthetic process;GO:0016126//sterol biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0032933//SREBP signaling pathway;GO:0036315//cellular response to sterol;GO:0036316//SREBP-SCAP complex retention in endoplasmic reticulum;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0042632//cholesterol homeostasis;GO:0045599//negative regulation of fat cell differentiation;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0060021//roof of mouth development;GO:0060363//cranial suture morphogenesis;GO:0070862//negative regulation of protein exit from endoplasmic reticulum;GO:1901303//negative regulation of cargo loading into COPII-coated vesicle	--
ENSG00000186487	0	0	0	0	0	0.058	0	0	0	0	0	3	MYT1L	myelin transcription factor 1 like [Source:HGNC Symbol;Acc:HGNC:7623]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0048663//neuron fate commitment;GO:0048665//neuron fate specification;GO:0048666//neuron development"	zf-C2HC
ENSG00000186496	2.585	1.663	2.069	0.747	1.128	0.995	145	123	110	42	67	55	ZNF396	zinc finger protein 396 [Source:HGNC Symbol;Acc:HGNC:18824]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000186501	20.704	22.972	25.257	26.623	22.852	26.561	656	731	589	627	613	611	TMEM222	transmembrane protein 222 [Source:HGNC Symbol;Acc:HGNC:25363]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000186509	0	0	0	0	0	0	0	0	0	0	0	0	OR9Q1	olfactory receptor family 9 subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:14724]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186510	0.269	0.077	0.262	0.229	0.221	0.39	12	4	8	9	10	15	CLCNKA	chloride voltage-gated channel Ka [Source:HGNC Symbol;Acc:HGNC:2026]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex	GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0030321//transepithelial chloride transport;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070293//renal absorption	--
ENSG00000186513	0	0	0	0	0	0	0	0	0	0	0	0	OR9Q2	olfactory receptor family 9 subfamily Q member 2 [Source:HGNC Symbol;Acc:HGNC:15328]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186517	0	0.025	0.067	0.05	0.197	0	0	2	4	3	7	0	ARHGAP30	Rho GTPase activating protein 30 [Source:HGNC Symbol;Acc:HGNC:27414]	-	-	-	-	GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000186522	19.563	14.893	16.2	12.897	14	16.01	1008	795	592	481	549	602	SEPTIN10	septin 10 [Source:HGNC Symbol;Acc:HGNC:14349]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0031105//septin complex;GO:0032153//cell division site	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0034613//cellular protein localization;GO:0051301//cell division;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000186523	3.729	3.4	3.837	3.708	3.842	3.53	145.45	131.49	104.23	101.33	129.75	94.47	FAM86B1	family with sequence similarity 86 member B1 [Source:HGNC Symbol;Acc:HGNC:28268]	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000186526	0	0	0	0	0	0	0	0	0	0	0	0	CYP4F8	cytochrome P450 family 4 subfamily F member 8 [Source:HGNC Symbol;Acc:HGNC:2648]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K17728;K17728	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0018685//alkane 1-monooxygenase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006693//prostaglandin metabolic process	--
ENSG00000186529	0.048	0	0.034	0	0.116	0	3	0	2	0	6	0	CYP4F3	cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K17726;K17726	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0070330//aromatase activity;GO:0097258//20-hydroxy-leukotriene B4 omega oxidase activity;GO:0097259//20-aldehyde-leukotriene B4 20-monooxygenase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity;GO:0102207//docosanoate omega-hydroxylase activity;GO:0120319//long-chain fatty acid omega-1 hydroxylase activity;GO:0140692//very long-chain fatty acid omega-hydroxylase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006690//icosanoid metabolic process;GO:0006691//leukotriene metabolic process;GO:0010430//fatty acid omega-oxidation;GO:0019369//arachidonic acid metabolic process;GO:0036101//leukotriene B4 catabolic process;GO:0042361//menaquinone catabolic process;GO:0042376//phylloquinone catabolic process;GO:0097267//omega-hydroxylase P450 pathway;GO:2001302//lipoxin A4 metabolic process;GO:2001304//lipoxin B4 metabolic process	--
ENSG00000186532	1.673	1.954	2.178	2.223	2.156	2.227	148	165	133	107	156	138	SMYD4	SET and MYND domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21067]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0007507//heart development;GO:0032259//methylation	--
ENSG00000186562	0	0	0	0	0	0	0	0	0	0	0	0	DEFB105A	defensin beta 105A [Source:HGNC Symbol;Acc:HGNC:18087]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000186564	0.073	0.091	0.123	0.025	0.043	0.05	4	5	5	1	2	2	FOXD2	forkhead box D2 [Source:HGNC Symbol;Acc:HGNC:3803]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	Fork_head
ENSG00000186566	8.328	8.555	7.326	6.587	8.345	8.07	1100	1100	750	665	802	800	GPATCH8	G-patch domain containing 8 [Source:HGNC Symbol;Acc:HGNC:29066]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0008150//biological_process	--
ENSG00000186567	0.953	0.652	0.53	0.832	0.939	0.72	38	26	18	26	33	22	CEACAM19	CEA cell adhesion molecule 19 [Source:HGNC Symbol;Acc:HGNC:31951]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000186572	0	0	0	0	0	0	0	0	0	0	0	0	DEFB107A	defensin beta 107A [Source:HGNC Symbol;Acc:HGNC:18086]	-	-	-	-	GO:0005576//extracellular region	GO:0008289//lipid binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000186575	10.362	10.134	10.996	8.771	12.903	11.12	928	917	741	604	850	705	NF2	neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773]	Cellular Processes;Environmental Information Processing;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction;Signal transduction	ko04530//Tight junction;ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K16684;K16684;K16684	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030864//cortical actin cytoskeleton;GO:0031527//filopodium membrane;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044297//cell body;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding	GO:0001707//mesoderm formation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0006469//negative regulation of protein kinase activity;GO:0007398//ectoderm development;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0014010//Schwann cell proliferation;GO:0014013//regulation of gliogenesis;GO:0021766//hippocampus development;GO:0022408//negative regulation of cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0031647//regulation of protein stability;GO:0035330//regulation of hippo signaling;GO:0042127//regulation of cell population proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042981//regulation of apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0045216//cell-cell junction organization;GO:0045597//positive regulation of cell differentiation;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0050767//regulation of neurogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0070306//lens fiber cell differentiation;GO:0072091//regulation of stem cell proliferation;GO:1900180//regulation of protein localization to nucleus;GO:2000177//regulation of neural precursor cell proliferation	--
ENSG00000186577	9.746	12.321	12.98	14.515	11.333	11.425	179	226	169	191	176	157	SMIM29	small integral membrane protein 29 [Source:HGNC Symbol;Acc:HGNC:1340]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186579	0	0	0	0	0	0	0	0	0	0	0	0	DEFB106A	defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:1990742//microvesicle	GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0031727//CCR2 chemokine receptor binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061760//antifungal innate immune response	--
ENSG00000186583	0	0	0	0	0.053	0	0	0	0	0	2	0	SPATC1	spermatogenesis and centriole associated 1 [Source:HGNC Symbol;Acc:HGNC:30510]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton	-	-	--
ENSG00000186591	40.369	40.687	37.978	33.528	39.502	41.728	3939	3653	2549	2447	2935	2612	UBE2H	ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10576	GO:0005634//nucleus;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000186599	0	0	0	0	0	0	0	0	0	0	0	0	DEFB105B	defensin beta 105B [Source:HGNC Symbol;Acc:HGNC:29930]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000186603	0.08	0.132	0.252	0.108	0.157	0.146	3	5	7	3	5	4	HPDL	4-hydroxyphenylpyruvate dioxygenase like [Source:HGNC Symbol;Acc:HGNC:28242]	-	-	-	-	GO:0005739//mitochondrion	"GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0009072//aromatic amino acid family metabolic process	--
ENSG00000186625	15.667	19.732	15.126	14.267	15.926	12.946	567	625	371	346	431	324	KATNA1	katanin catalytic subunit A1 [Source:HGNC Symbol;Acc:HGNC:6216]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0097431//mitotic spindle pole	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008568//microtubule-severing ATPase activity;GO:0016853//isomerase activity;GO:0016887//ATP hydrolysis activity;GO:0046982//protein heterodimerization activity	GO:0007049//cell cycle;GO:0051013//microtubule severing;GO:0051301//cell division	--
ENSG00000186628	0.068	0.045	0.092	0.041	0.08	0.093	9	6	9	4	9	9	FSD2	fibronectin type III and SPRY domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18024]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	-	--
ENSG00000186635	25.922	22.478	31.552	27.25	32.612	27.832	1648	1639	1419	1438	1622	1395	ARAP1	"ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K18439	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding"	GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0030037//actin filament reorganization involved in cell cycle;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051270//regulation of cellular component movement;GO:0051491//positive regulation of filopodium assembly;GO:0051497//negative regulation of stress fiber assembly	--
ENSG00000186638	2.5	2.433	2.161	1.228	1.314	1.316	304	317	186	97	145	125	KIF24	kinesin family member 24 [Source:HGNC Symbol;Acc:HGNC:19916]	Organismal Systems	Development and regeneration	ko04361//Axon regeneration	K10393	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding	GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1902018//negative regulation of cilium assembly	--
ENSG00000186642	0.843	1.368	1.357	1.446	1.49	0.689	33	57	31	39	48	26	PDE2A	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]	Metabolism;Organismal Systems;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Sensory system;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	ko01100//Metabolic pathways;ko04740//Olfactory transduction;ko04022//cGMP-PKG signaling pathway;ko00230//Purine metabolism;ko04925//Aldosterone synthesis and secretion;ko05032//Morphine addiction	K18283;K18283;K18283;K18283;K18283;K18283	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042734//presynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0030911//TPR domain binding;GO:0042301//phosphate ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003170//heart valve development;GO:0003281//ventricular septum development;GO:0007165//signal transduction;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010752//regulation of cGMP-mediated signaling;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0010821//regulation of mitochondrion organization;GO:0019933//cAMP-mediated signaling;GO:0019934//cGMP-mediated signaling;GO:0030224//monocyte differentiation;GO:0035904//aorta development;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0043116//negative regulation of vascular permeability;GO:0043117//positive regulation of vascular permeability;GO:0043949//regulation of cAMP-mediated signaling;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0046069//cGMP catabolic process;GO:0050729//positive regulation of inflammatory response;GO:0061028//establishment of endothelial barrier;GO:0071260//cellular response to mechanical stimulus;GO:0071320//cellular response to cAMP;GO:0071321//cellular response to cGMP;GO:0071466//cellular response to xenobiotic stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:1904613//cellular response to 2,3,7,8-tetrachlorodibenzodioxine"	--
ENSG00000186645	0	0	0.024	0	0	0.119	0	0	1.07	0	0	5.19	SPDYE17	speedy/RINGO cell cycle regulator family member E17 [Source:HGNC Symbol;Acc:HGNC:51513]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000186648	0.137	0.146	0.085	0.227	0.224	0.159	13	14	6	16	18	11	CARMIL3	capping protein regulator and myosin 1 linker 3 [Source:HGNC Symbol;Acc:HGNC:20272]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000186652	0	0	0	0	0	0	0	0	0	0	0	0	PRG2	"proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362]"	Human Diseases	Immune disease	ko05310//Asthma	K10786	GO:0005576//extracellular region;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance;GO:0030246//carbohydrate binding	GO:0002376//immune system process;GO:0006955//immune response;GO:0042742//defense response to bacterium	--
ENSG00000186654	17.691	19.94	18.514	23.861	22.283	22.958	663.62	751	509	671.71	714.16	617.22	PRR5	proline rich 5 [Source:HGNC Symbol;Acc:HGNC:31682]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20411	GO:0005829//cytosol;GO:0031932//TORC2 complex	GO:0005515//protein binding	GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0030307//positive regulation of cell growth;GO:0031669//cellular response to nutrient levels;GO:0038203//TORC2 signaling;GO:0043066//negative regulation of apoptotic process	--
ENSG00000186660	13.205	12.294	11.889	9.068	10.304	11.597	1582	1480.41	1052	804.71	1043	1010.91	ZFP91	"ZFP91 zinc finger protein, atypical E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:14983]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0016567//protein ubiquitination;GO:0070534//protein K63-linked ubiquitination	zf-C2H2
ENSG00000186665	2.056	1.598	2.346	2.567	3.194	2.271	53	46	49	53	78	46	C17orf58	chromosome 17 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:27568]	-	-	-	-	GO:0005576//extracellular region;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000186666	2.065	1.964	2.249	2.225	2.057	2.044	138.19	132.12	111.13	110.26	116.27	99.51	BCDIN3D	BCDIN3 domain containing RNA methyltransferase [Source:HGNC Symbol;Acc:HGNC:27050]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016740//transferase activity	GO:0001510//RNA methylation;GO:0010586//miRNA metabolic process;GO:0030488//tRNA methylation;GO:0032259//methylation;GO:0061715//miRNA 2'-O-methylation;GO:2000632//negative regulation of pre-miRNA processing	--
ENSG00000186675	0.128	0.042	0	0	0	0	6	2	0	0	0	0	MAGEE2	MAGE family member E2 [Source:HGNC Symbol;Acc:HGNC:24935]	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000186684	2.492	1.888	1.914	1.725	1.851	1.911	251	200	144	120	152	139	CYP27C1	cytochrome P450 family 27 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:33480]	Metabolism	Metabolism of cofactors and vitamins	ko00830//Retinol metabolism	K17951	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0001972//retinoic acid binding;GO:0004497//monooxygenase activity;GO:0005502//11-cis retinal binding;GO:0005503//all-trans retinal binding;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0061896//all-trans retinol 3,4-desaturase activity;GO:0061897//all-trans retinal 3,4-desaturase activity;GO:0061898//all-trans retinoic acid 3,4-desaturase activity;GO:0061899//11-cis-retinal 3,4-desaturase activity;GO:1904768//all-trans-retinol binding"	GO:0006629//lipid metabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process	--
ENSG00000186687	4.316	5.145	2.236	1.999	1.936	2.405	365	281	213	191	211	181	LYRM7	LYR motif containing 7 [Source:HGNC Symbol;Acc:HGNC:28072]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0045333//cellular respiration	--
ENSG00000186710	0.126	0.092	0.433	0.083	0.184	0.044	4.31	3.15	10.93	2.1	5.3	1.09	CFAP73	cilia and flagella associated protein 73 [Source:HGNC Symbol;Acc:HGNC:37100]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097545//axonemal outer doublet	GO:0070840//dynein complex binding	GO:0003341//cilium movement;GO:0036159//inner dynein arm assembly	--
ENSG00000186714	0	0	0	0	0	0	0	0	0	0	0	0	CCDC73	coiled-coil domain containing 73 [Source:HGNC Symbol;Acc:HGNC:23261]	-	-	-	-	-	-	-	--
ENSG00000186716	26.621	26.76	25.029	28.726	28.553	27.202	3534	3614	2532	2826	3128	2648	BCR	BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko05220//Chronic myeloid leukemia	K08878;K08878	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0002692//negative regulation of cellular extravasation;GO:0003014//renal system process;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0030216//keratinocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0032496//response to lipopolysaccharide;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0042472//inner ear morphogenesis;GO:0043114//regulation of vascular permeability;GO:0043314//negative regulation of neutrophil degranulation;GO:0043547//positive regulation of GTPase activity;GO:0048041//focal adhesion assembly;GO:0048872//homeostasis of number of cells;GO:0050728//negative regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050804//modulation of chemical synaptic transmission;GO:0050885//neuromuscular process controlling balance;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051171//regulation of nitrogen compound metabolic process;GO:0051726//regulation of cell cycle;GO:0060216//definitive hemopoiesis;GO:0060268//negative regulation of respiratory burst;GO:0060313//negative regulation of blood vessel remodeling;GO:0065002//intracellular protein transmembrane transport;GO:0071222//cellular response to lipopolysaccharide;GO:0090630//activation of GTPase activity;GO:2000378//negative regulation of reactive oxygen species metabolic process	--
ENSG00000186723	0	0.033	0.045	0	0	0	0	3	3	0	0	0	OR10H1	olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000186732	0.281	0.154	0.197	0.17	0.216	0.212	20	11	5	9	13	11	MPPED1	metallophosphoesterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1306]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0016787//hydrolase activity	GO:0008150//biological_process	--
ENSG00000186765	1.472	0.392	1.079	0.753	0.651	0.407	51	13	27	19	19	10	FSCN2	"fascin actin-bundling protein 2, retinal [Source:HGNC Symbol;Acc:HGNC:3960]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0032420//stereocilium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007601//visual perception;GO:0009653//anatomical structure morphogenesis;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0042462//eye photoreceptor cell development;GO:0051017//actin filament bundle assembly	--
ENSG00000186766	0	0	0	0	0	0	0	0	0	0	0	0	FOXI2	forkhead box I2 [Source:HGNC Symbol;Acc:HGNC:32448]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000186767	1.257	0.701	0.986	1.316	0.751	1.017	107	60	62	83	54	63	SPIN4	spindlin family member 4 [Source:HGNC Symbol;Acc:HGNC:27040]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007276//gamete generation"	--
ENSG00000186777	0.103	0.11	0.083	0.055	0.073	0.085	5	5	3	2	3	3	ZNF732	zinc finger protein 732 [Source:HGNC Symbol;Acc:HGNC:37138]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000186787	3.26	1.692	2.973	3.011	2.82	3.338	79.45	42.05	56.65	56	56	48.17	SPIN2B	spindlin family member 2B [Source:HGNC Symbol;Acc:HGNC:33147]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007276//gamete generation;GO:0051726//regulation of cell cycle"	--
ENSG00000186788	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31D3	SPATA31 subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:38603]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000186790	0	0.136	0	0	0	0	0	5	0	0	0	0	FOXE3	forkhead box E3 [Source:HGNC Symbol;Acc:HGNC:3808]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0001654//eye development;GO:0002088//lens development in camera-type eye;GO:0002930//trabecular meshwork development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0048468//cell development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0051726//regulation of cell cycle;GO:0061072//iris morphogenesis;GO:0061073//ciliary body morphogenesis;GO:0061303//cornea development in camera-type eye;GO:1902747//negative regulation of lens fiber cell differentiation;GO:2001111//positive regulation of lens epithelial cell proliferation"	Fork_head
ENSG00000186792	13.804	14.104	13.697	10.606	10.194	12.712	477	485	359	257	311	305.41	HYAL3	hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01197;K01197;K01197	GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0097225//sperm midpiece	"GO:0003824//catalytic activity;GO:0004415//hyalurononglucosaminidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0033906//hyaluronoglucuronidase activity"	GO:0001552//ovarian follicle atresia;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response;GO:0007338//single fertilization;GO:0007341//penetration of zona pellucida;GO:0008152//metabolic process;GO:0009615//response to virus;GO:0030214//hyaluronan catabolic process;GO:0046677//response to antibiotic;GO:0051216//cartilage development;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071493//cellular response to UV-B;GO:2000355//negative regulation of ovarian follicle development;GO:2000368//positive regulation of acrosomal vesicle exocytosis	--
ENSG00000186795	0	0	0	0	0	0	0	0	0	0	0	0	KCNK18	potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005267//potassium channel activity;GO:0015269//calcium-activated potassium channel activity;GO:0015271//outward rectifier potassium channel activity;GO:0022841//potassium ion leak channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0030322//stabilization of membrane potential;GO:0071467//cellular response to pH;GO:0071805//potassium ion transmembrane transport;GO:0097623//potassium ion export across plasma membrane	--
ENSG00000186803	0	0	0	0	0	0	0	0	0	0	0	0	IFNA10	interferon alpha 10 [Source:HGNC Symbol;Acc:HGNC:5418]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000186806	0.876	0.936	0.672	1.482	1.609	1.096	67	72	38	84	104	61	VSIG10L	V-set and immunoglobulin domain containing 10 like [Source:HGNC Symbol;Acc:HGNC:27111]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186810	0	0	0	0	0	0	0	0	0	0	0	0	CXCR3	C-X-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:4540]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K04188;K04188;K04188	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0016493//C-C chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0019956//chemokine binding;GO:0019957//C-C chemokine binding;GO:0019958//C-X-C chemokine binding;GO:0038023//signaling receptor activity	GO:0001525//angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002685//regulation of leukocyte migration;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell population proliferation;GO:0016525//negative regulation of angiogenesis;GO:0019722//calcium-mediated signaling;GO:0030155//regulation of cell adhesion;GO:0045766//positive regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050921//positive regulation of chemotaxis;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:1900118//negative regulation of execution phase of apoptosis;GO:1900119//positive regulation of execution phase of apoptosis	--
ENSG00000186812	7.804	6.267	8.509	5.149	4.829	5.874	536.06	409	316	259	319	294	ZNF397	zinc finger protein 397 [Source:HGNC Symbol;Acc:HGNC:18818]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000186814	7.092	7.395	6.573	5.592	6.84	8.076	522	507	341	297	351	351	ZSCAN30	zinc finger and SCAN domain containing 30 [Source:HGNC Symbol;Acc:HGNC:33517]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000186815	10.352	12.084	11.039	12.101	14.11	11.313	1050	1239	826	879	1154	714	TPCN1	two pore segment channel 1 [Source:HGNC Symbol;Acc:HGNC:18182]	Environmental Information Processing	Signal transduction	ko04020//Calcium signaling pathway	K16896	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0036019//endolysosome;GO:0055038//recycling endosome membrane	"GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015280//ligand-gated sodium channel activity;GO:0019905//syntaxin binding;GO:0022832//voltage-gated channel activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0097682//intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity"	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0010508//positive regulation of autophagy;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0075509//endocytosis involved in viral entry into host cell	--
ENSG00000186818	0	0	0	0	0	0	0	0	0	0	0	0	LILRB4	leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0098752//integral component of the cytoplasmic side of the plasma membrane	GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030293//transmembrane receptor protein tyrosine kinase inhibitor activity;GO:0030547//signaling receptor inhibitor activity;GO:0034185//apolipoprotein binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002507//tolerance induction;GO:0002669//positive regulation of T cell anergy;GO:0002725//negative regulation of T cell cytokine production;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0031623//receptor internalization;GO:0032682//negative regulation of chemokine production;GO:0032689//negative regulation of interferon-gamma production;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032693//negative regulation of interleukin-10 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032714//negative regulation of interleukin-5 production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0042130//negative regulation of T cell proliferation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0043409//negative regulation of MAPK cascade;GO:0045584//negative regulation of cytotoxic T cell differentiation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0046007//negative regulation of activated T cell proliferation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0071659//negative regulation of IP-10 production;GO:0140105//interleukin-10-mediated signaling pathway;GO:0150102//negative regulation of monocyte activation;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1900181//negative regulation of protein localization to nucleus;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:2000272//negative regulation of signaling receptor activity;GO:2000524//negative regulation of T cell costimulation"	--
ENSG00000186827	0	0	0	0	0	0	0	0	0	0	0	0	TNFRSF4	TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05142	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding	"GO:0002639//positive regulation of immunoglobulin production;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030890//positive regulation of B cell proliferation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042098//T cell proliferation;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell"	--
ENSG00000186832	0.183	0.087	0.215	0	0.218	0.396	5	3	3	0	5	6	KRT16	keratin 16 [Source:HGNC Symbol;Acc:HGNC:6423]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0002009//morphogenesis of an epithelium;GO:0006954//inflammatory response;GO:0007010//cytoskeleton organization;GO:0007568//aging;GO:0030216//keratinocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0030855//epithelial cell differentiation;GO:0031424//keratinization;GO:0042633//hair cycle;GO:0045087//innate immune response;GO:0045104//intermediate filament cytoskeleton organization;GO:0045109//intermediate filament organization;GO:0051546//keratinocyte migration;GO:0061436//establishment of skin barrier	--
ENSG00000186834	9.828	9.725	10.138	10.611	10.201	10.949	739	735	563	591	648	599	HEXIM1	HEXIM P-TEFb complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24953]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0120259//7SK snRNP	GO:0004860//protein kinase inhibitor activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0042802//identical protein binding;GO:0097322//7SK snRNA binding;GO:0106140//P-TEFb complex binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0007507//heart development;GO:0032897//negative regulation of viral transcription;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:1901798//positive regulation of signal transduction by p53 class mediator"	--
ENSG00000186838	0	0	0	0	0	0	0	0	0	0	0	0	SELENOV	selenoprotein V [Source:HGNC Symbol;Acc:HGNC:30399]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0010269//response to selenium ion	--
ENSG00000186844	0	0	0	0	0	0	0	0	0	0	0	0	LCE1A	late cornified envelope 1A [Source:HGNC Symbol;Acc:HGNC:29459]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000186847	0	0.029	0	0	0.035	0	0	1	0	0	1	0	KRT14	keratin 14 [Source:HGNC Symbol;Acc:HGNC:6416]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0045178//basal part of cell;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:1990254//keratin filament binding	GO:0007568//aging;GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0042633//hair cycle;GO:0045109//intermediate filament organization;GO:0045110//intermediate filament bundle assembly	--
ENSG00000186854	0.031	0.031	0	0	0.031	0	1	1	0	0	1	0	TRABD2A	TraB domain containing 2A [Source:HGNC Symbol;Acc:HGNC:27013]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031301//integral component of organelle membrane	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017147//Wnt-protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031334//positive regulation of protein-containing complex assembly;GO:0060322//head development;GO:1904808//positive regulation of protein oxidation	--
ENSG00000186860	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP17-1	keratin associated protein 17-1 [Source:HGNC Symbol;Acc:HGNC:18917]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186862	0.45	0.473	0.128	0.407	0.42	0.208	26	27	4	18	18	10	PDZD7	PDZ domain containing 7 [Source:HGNC Symbol;Acc:HGNC:26257]	-	-	-	-	GO:0002141//stereocilia ankle link;GO:0002142//stereocilia ankle link complex;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:1990696//USH2 complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007605//sensory perception of sound;GO:0045184//establishment of protein localization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060088//auditory receptor cell stereocilium organization;GO:0060117//auditory receptor cell development	--
ENSG00000186866	12.493	12.992	14.783	11.31	12.535	11.546	773	808	632	491	651	518	POFUT2	protein O-fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:14683]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K03691	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046922//peptide-O-fucosyltransferase activity	GO:0001707//mesoderm formation;GO:0005975//carbohydrate metabolic process;GO:0006004//fucose metabolic process;GO:0006486//protein glycosylation;GO:0010468//regulation of gene expression;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0036065//fucosylation;GO:0036066//protein O-linked fucosylation;GO:0051046//regulation of secretion;GO:1903334//positive regulation of protein folding	--
ENSG00000186867	0	0	0.084	0.054	0	0	0	0	3	1	0	0	QRFPR	pyroglutamylated RFamide peptide receptor [Source:HGNC Symbol;Acc:HGNC:15565]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000186868	0.797	0.63	0.47	0.939	0.972	0.714	60	61	28	47	62	43	MAPT	microtubule associated protein tau [Source:HGNC Symbol;Acc:HGNC:6893]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko05012//Parkinson disease	K04380;K04380;K04380;K04380	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030673//axolemma;GO:0034399//nuclear periphery;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0036477//somatodendritic compartment;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0044297//cell body;GO:0044304//main axon;GO:0045121//membrane raft;GO:0045298//tubulin complex;GO:0097386//glial cell projection;GO:0097418//neurofibrillary tangle;GO:1904115//axon cytoplasm	GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030674//protein-macromolecule adaptor activity;GO:0034185//apolipoprotein binding;GO:0034452//dynactin binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0051087//chaperone binding;GO:0051721//protein phosphatase 2A binding;GO:0051879//Hsp90 protein binding;GO:0071813//lipoprotein particle binding;GO:0099077//histone-dependent DNA binding;GO:0099609//microtubule lateral binding;GO:1902936//phosphatidylinositol bisphosphate binding	GO:0000226//microtubule cytoskeleton organization;GO:0001774//microglial cell activation;GO:0006475//internal protein amino acid acetylation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007267//cell-cell signaling;GO:0007416//synapse assembly;GO:0007611//learning or memory;GO:0007613//memory;GO:0010288//response to lead ion;GO:0010506//regulation of autophagy;GO:0010629//negative regulation of gene expression;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0016072//rRNA metabolic process;GO:0019896//axonal transport of mitochondrion;GO:0021954//central nervous system neuron development;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031113//regulation of microtubule polymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development;GO:0032930//positive regulation of superoxide anion generation;GO:0033044//regulation of chromosome organization;GO:0033673//negative regulation of kinase activity;GO:0034063//stress granule assembly;GO:0034605//cellular response to heat;GO:0034614//cellular response to reactive oxygen species;GO:0045773//positive regulation of axon extension;GO:0046785//microtubule polymerization;GO:0048143//astrocyte activation;GO:0048167//regulation of synaptic plasticity;GO:0048312//intracellular distribution of mitochondria;GO:0048699//generation of neurons;GO:0050808//synapse organization;GO:0050848//regulation of calcium-mediated signaling;GO:0051258//protein polymerization;GO:0051260//protein homooligomerization;GO:0061564//axon development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0072386//plus-end-directed organelle transport along microtubule;GO:0090140//regulation of mitochondrial fission;GO:0090258//negative regulation of mitochondrial fission;GO:0097435//supramolecular fiber organization;GO:0098930//axonal transport;GO:1900034//regulation of cellular response to heat;GO:1900452//regulation of long-term synaptic depression;GO:1901216//positive regulation of neuron death;GO:1902474//positive regulation of protein localization to synapse;GO:1902988//neurofibrillary tangle assembly;GO:1903748//negative regulation of establishment of protein localization to mitochondrion;GO:1903829//positive regulation of cellular protein localization;GO:1904428//negative regulation of tubulin deacetylation;GO:1905689//positive regulation of diacylglycerol kinase activity;GO:1990000//amyloid fibril formation;GO:1990090//cellular response to nerve growth factor stimulus;GO:1990416//cellular response to brain-derived neurotrophic factor stimulus;GO:2001020//regulation of response to DNA damage stimulus	--
ENSG00000186871	0.16	0.193	0.124	0.139	0.081	0.063	14	17	8	9	6	4	ERCC6L	"ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794]"	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005829//cytosol;GO:0016020//membrane"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015616//DNA translocase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006338//chromatin remodeling;GO:0007049//cell cycle;GO:0032508//DNA duplex unwinding;GO:0051301//cell division	--
ENSG00000186881	0	0	0	0	0	0	0	0	0	0	0	0	OR13F1	olfactory receptor family 13 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:14723]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186886	0	0	0	0	0	0	0	0	0	0	0	0	OR5D3P	olfactory receptor family 5 subfamily D member 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:8336]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186889	1.574	2.291	1.342	1.417	1.725	2.043	54	79	34	36	50	51	TMEM17	transmembrane protein 17 [Source:HGNC Symbol;Acc:HGNC:26623]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000186891	0.89	0.889	0.603	0.726	0.193	0.078	20	16	10	8	3	1	TNFRSF18	TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05154	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding	GO:0002687//positive regulation of leukocyte migration;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043066//negative regulation of apoptotic process;GO:0045785//positive regulation of cell adhesion	--
ENSG00000186895	0	0	0	0	0	0	0	0	0	0	0	0	FGF3	fibroblast growth factor 3 [Source:HGNC Symbol;Acc:HGNC:3681]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0051781//positive regulation of cell division;GO:0055026//negative regulation of cardiac muscle tissue development	--
ENSG00000186897	0.186	0.046	0.157	0	0	0	8	2	5	0	0	0	C1QL4	complement C1q like 4 [Source:HGNC Symbol;Acc:HGNC:31416]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0045599//negative regulation of fat cell differentiation;GO:0048147//negative regulation of fibroblast proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000186907	0.241	0.345	0.419	0.468	0.616	0.842	9	16	10	16	24	23	RTN4RL2	reticulon 4 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:23053]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0010977//negative regulation of neuron projection development;GO:0031103//axon regeneration	--
ENSG00000186908	6.281	5.206	4.044	3.834	4.487	4.789	496	417	245	251	304	305	ZDHHC17	zinc finger DHHC-type palmitoyltransferase 17 [Source:HGNC Symbol;Acc:HGNC:18412]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016235//aggresome;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019705//protein-cysteine S-myristoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0042802//identical protein binding;GO:0140439//protein-cysteine S-stearoyltransferase activity	GO:0007409//axonogenesis;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0042953//lipoprotein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051386//regulation of neurotrophin TRK receptor signaling pathway;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:1903830//magnesium ion transmembrane transport	--
ENSG00000186910	0	0	0	0	0	0	0	0	0	0	0	0	SERPINA11	serpin family A member 11 [Source:HGNC Symbol;Acc:HGNC:19193]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000186912	0.024	0.047	0.064	0	0.028	0	1	2	2	0	1	0	P2RY4	pyrimidinergic receptor P2Y4 [Source:HGNC Symbol;Acc:HGNC:8542]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04742//Taste transduction	K04271;K04271	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0098978//glutamatergic synapse;GO:0099059//integral component of presynaptic active zone membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0045028//G protein-coupled purinergic nucleotide receptor activity;GO:0045030//G protein-coupled UTP receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030321//transepithelial chloride transport;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0071318//cellular response to ATP;GO:0071380//cellular response to prostaglandin E stimulus;GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000186918	14.886	16.69	14.866	18.026	19.629	15.894	1320.98	1343	888	1137	1239	983	ZNF395	zinc finger protein 395 [Source:HGNC Symbol;Acc:HGNC:18737]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	Others
ENSG00000186919	0	0	0	0	0	0	0	0	0	0	0	0	ZACN	zinc activated ion channel [Source:HGNC Symbol;Acc:HGNC:29504]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0008270//zinc ion binding;GO:0015276//ligand-gated ion channel activity;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0010043//response to zinc ion;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process	--
ENSG00000186924	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP22-1	keratin associated protein 22-1 [Source:HGNC Symbol;Acc:HGNC:18947]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000186925	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-6	keratin associated protein 19-6 [Source:HGNC Symbol;Acc:HGNC:18941]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186930	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP6-2	keratin associated protein 6-2 [Source:HGNC Symbol;Acc:HGNC:18932]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0031424//keratinization	--
ENSG00000186943	0	0	0	0	0	0	0	0	0	0	0	0	OR13C8	olfactory receptor family 13 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:15103]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000186951	17.451	16.959	15.993	17.387	20.168	18.245	3008	2736	2185	2368	2672	2337	PPARA	peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Cardiovascular disease;Cancer: overview;Endocrine and metabolic disease;Infectious disease: viral;Endocrine and metabolic disease;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system	ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05207//Chemical carcinogenesis - receptor activation;ko04932//Non-alcoholic fatty liver disease;ko05160//Hepatitis C;ko04936//Alcoholic liver disease;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway	K07294;K07294;K07294;K07294;K07294;K07294;K07294;K07294;K07294;K07294	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001223//transcription coactivator binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0019902//phosphatase binding;GO:0019904//protein domain specific binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0038023//signaling receptor activity;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0051525//NFAT protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001666//response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006631//fatty acid metabolic process;GO:0007154//cell communication;GO:0007507//heart development;GO:0008544//epidermis development;GO:0009267//cellular response to starvation;GO:0009755//hormone-mediated signaling pathway;GO:0010468//regulation of gene expression;GO:0010565//regulation of cellular ketone metabolic process;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010876//lipid localization;GO:0010883//regulation of lipid storage;GO:0010887//negative regulation of cholesterol storage;GO:0010891//negative regulation of sequestering of triglyceride;GO:0014070//response to organic cyclic compound;GO:0019216//regulation of lipid metabolic process;GO:0019217//regulation of fatty acid metabolic process;GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030522//intracellular receptor signaling pathway;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0032091//negative regulation of protein binding;GO:0032099//negative regulation of appetite;GO:0032868//response to insulin;GO:0032922//circadian regulation of gene expression;GO:0033993//response to lipid;GO:0035095//behavioral response to nicotine;GO:0042060//wound healing;GO:0042157//lipoprotein metabolic process;GO:0042752//regulation of circadian rhythm;GO:0043401//steroid hormone mediated signaling pathway;GO:0045070//positive regulation of viral genome replication;GO:0045471//response to ethanol;GO:0045722//positive regulation of gluconeogenesis;GO:0045776//negative regulation of blood pressure;GO:0045820//negative regulation of glycolytic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045923//positive regulation of fatty acid metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046321//positive regulation of fatty acid oxidation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048511//rhythmic process;GO:0050728//negative regulation of inflammatory response;GO:0051716//cellular response to stimulus;GO:0051898//negative regulation of protein kinase B signaling;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0070166//enamel mineralization;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1901215//negative regulation of neuron death;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903944//negative regulation of hepatocyte apoptotic process;GO:2000191//regulation of fatty acid transport;GO:2000272//negative regulation of signaling receptor activity;GO:2001171//positive regulation of ATP biosynthetic process"	THR-like
ENSG00000186952	0.691	0.8	1.252	0.853	0.856	0.612	27	45	20	25	20	16	TMEM232	transmembrane protein 232 [Source:HGNC Symbol;Acc:HGNC:37270]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000186965	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-2	keratin associated protein 19-2 [Source:HGNC Symbol;Acc:HGNC:18937]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186967	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-4	keratin associated protein 19-4 [Source:HGNC Symbol;Acc:HGNC:18939]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186970	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP15-1	keratin associated protein 15-1 [Source:HGNC Symbol;Acc:HGNC:18927]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186971	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP13-4	keratin associated protein 13-4 [Source:HGNC Symbol;Acc:HGNC:18926]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186973	0.541	0.301	0.122	0.13	0.108	0	6	3	1	1	1	0	FAM183A	family with sequence similarity 183 member A [Source:HGNC Symbol;Acc:HGNC:34347]	-	-	-	-	GO:0097546//ciliary base	-	-	--
ENSG00000186976	1.507	1.057	0.692	0.81	0.508	0.255	78	77	41	45	37	17	EFCAB6	EF-hand calcium binding domain 6 [Source:HGNC Symbol;Acc:HGNC:24204]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000186977	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-5	keratin associated protein 19-5 [Source:HGNC Symbol;Acc:HGNC:18940]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186980	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP23-1	keratin associated protein 23-1 [Source:HGNC Symbol;Acc:HGNC:18928]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000186994	2.148	2.377	1.642	2.204	1.721	1.072	124.15	138.09	70.1	94.38	84.04	45.09	KANK3	KN motif and ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:24796]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0030837//negative regulation of actin filament polymerization	--
ENSG00000186998	5.771	6.334	5.772	4.346	5.176	3.456	231	253	172	133	188	111	EMID1	EMI domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18036]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0031012//extracellular matrix;GO:0071944//cell periphery	GO:0005515//protein binding	-	--
ENSG00000187003	0	0	0	0	0	0	0	0	0	0	0	0	ACTL7A	actin like 7A [Source:HGNC Symbol;Acc:HGNC:161]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005869//dynactin complex;GO:0031514//motile cilium;GO:0032991//protein-containing complex	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0001675//acrosome assembly;GO:0007010//cytoskeleton organization;GO:0009566//fertilization	--
ENSG00000187005	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP21-1	keratin associated protein 21-1 [Source:HGNC Symbol;Acc:HGNC:18945]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	GO:0001942//hair follicle development	--
ENSG00000187010	0.034	0	0	0.069	0.041	0	2	0	0	3	2	0	RHD	Rh blood group D antigen [Source:HGNC Symbol;Acc:HGNC:10009]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity	GO:0015696//ammonium transport;GO:0072488//ammonium transmembrane transport	--
ENSG00000187017	5.979	6.8	6.671	14.64	14.332	8.198	160	166	149	277	264	162	ESPN	espin [Source:HGNC Symbol;Acc:HGNC:13281]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0005903//brush border;GO:0031941//filamentous actin;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0051015//actin filament binding	GO:0007605//sensory perception of sound;GO:0030034//microvillar actin bundle assembly;GO:0051017//actin filament bundle assembly	--
ENSG00000187021	0	0	0	0	0	0	0	0	0	0	0	0	PNLIPRP1	pancreatic lipase related protein 1 [Source:HGNC Symbol;Acc:HGNC:9156]	Metabolism;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Digestive system;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K14074;K14074;K14074;K14074	GO:0005576//extracellular region	GO:0004806//triglyceride lipase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process	--
ENSG00000187024	6.03	6.398	5.693	8.206	7.303	5.622	113.76	121.44	85.93	119	117.99	78.59	PTRH1	peptidyl-tRNA hydrolase 1 homolog [Source:HGNC Symbol;Acc:HGNC:27039]	-	-	-	-	-	GO:0003723//RNA binding;GO:0004045//aminoacyl-tRNA hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	-	--
ENSG00000187026	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP21-2	keratin associated protein 21-2 [Source:HGNC Symbol;Acc:HGNC:18946]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000187033	0	0	0	0	0	0	0	0	0	0	0	0	SAMD7	sterile alpha motif domain containing 7 [Source:HGNC Symbol;Acc:HGNC:25394]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0010629//negative regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000187037	0	0	0	0.058	0	0	0	0	0	2	0	0	GPR141	G protein-coupled receptor 141 [Source:HGNC Symbol;Acc:HGNC:19997]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000187045	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS6	transmembrane serine protease 6 [Source:HGNC Symbol;Acc:HGNC:16517]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006879//cellular iron ion homeostasis;GO:0022617//extracellular matrix disassembly;GO:0030514//negative regulation of BMP signaling pathway;GO:0030574//collagen catabolic process;GO:0033619//membrane protein proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0055072//iron ion homeostasis;GO:0097264//self proteolysis"	--
ENSG00000187048	0	0	0	0	0	0	0	0	0	0	0	0	CYP4A11	cytochrome P450 family 4 subfamily A member 11 [Source:HGNC Symbol;Acc:HGNC:2642]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0018685//alkane 1-monooxygenase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0070330//aromatase activity;GO:0102033//long-chain fatty acid omega-hydroxylase activity"	GO:0001676//long-chain fatty acid metabolic process;GO:0001822//kidney development;GO:0003091//renal water homeostasis;GO:0003095//pressure natriuresis;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006691//leukotriene metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0031408//oxylipin biosynthetic process;GO:0032305//positive regulation of icosanoid secretion;GO:0036101//leukotriene B4 catabolic process;GO:0043651//linoleic acid metabolic process;GO:0046456//icosanoid biosynthetic process;GO:0048252//lauric acid metabolic process;GO:0055078//sodium ion homeostasis;GO:0097267//omega-hydroxylase P450 pathway	--
ENSG00000187049	8.031	9.192	7.704	9.266	6.792	8.683	174	201	124	150	123	138	TMEM216	transmembrane protein 216 [Source:HGNC Symbol;Acc:HGNC:25018]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000187051	24.635	29.137	34.481	29.468	28.379	31.747	420	500	434	373	410	394	RPS19BP1	ribosomal protein S19 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28749]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding	-	--
ENSG00000187054	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS11A	transmembrane serine protease 11A [Source:HGNC Symbol;Acc:HGNC:27954]	-	-	-	-	GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007049//cell cycle	--
ENSG00000187066	0	0	0	0	0	0	0	0	0	0	0	0	TMEM262	transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036128//CatSper complex	GO:0005515//protein binding	-	--
ENSG00000187068	0.391	0.281	0.182	0.027	0.056	0.111	58	42	20	3	7	12	C3orf70	chromosome 3 open reading frame 70 [Source:HGNC Symbol;Acc:HGNC:33731]	-	-	-	-	-	-	GO:0007399//nervous system development;GO:0048512//circadian behavior	--
ENSG00000187079	15.61	11.807	11.736	10.482	14.383	14.222	2528	2132	1441	1317	1661	1476	TEAD1	TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K09448;K09448	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0140552//TEAD-YAP complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030307//positive regulation of cell growth;GO:0035329//hippo signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0065003//protein-containing complex assembly;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	TEA
ENSG00000187080	0	0	0	0	0	0	0	0	0	0	0	0	OR2AK2	olfactory receptor family 2 subfamily AK member 2 [Source:HGNC Symbol;Acc:HGNC:19569]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187082	0	0	0	0	0	0	0	0	0	0	0	0	DEFB106B	defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:1990742//microvesicle	GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0031727//CCR2 chemokine receptor binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061760//antifungal innate immune response	--
ENSG00000187091	16.453	16.017	16.379	15.896	16.527	13.979	926	914	690	674	797	575	PLCD1	phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060]	Metabolism;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Infectious disease: bacterial;Endocrine system;Endocrine and metabolic disease;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04020//Calcium signaling pathway;ko05131//Shigellosis;ko04919//Thyroid hormone signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K05857;K05857;K05857;K05857;K05857;K05857;K05857	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	"GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0032794//GTPase activating protein binding;GO:0046872//metal ion binding"	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000187094	0.194	0.405	0.079	0.706	0.382	0.84	3	7	1	9	5	10	CCK	cholecystokinin [Source:HGNC Symbol;Acc:HGNC:1569]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Digestive system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04972//Pancreatic secretion;ko04911//Insulin secretion	K05226;K05226;K05226	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030424//axon	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0051428//peptide hormone receptor binding	GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0007586//digestion;GO:0042755//eating behavior	--
ENSG00000187097	4.675	4.969	4.677	3.49	4.41	4.261	476.51	476.04	347.67	257.13	383	298.54	ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5 (inactive) [Source:HGNC Symbol;Acc:HGNC:3367]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01511;K01511;K01511	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0045134//uridine-diphosphatase activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0009134//nucleoside diphosphate catabolic process;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0045821//positive regulation of glycolytic process;GO:0046034//ATP metabolic process;GO:0051084//'de novo' posttranslational protein folding	--
ENSG00000187098	97.566	84.192	82.668	56.279	71.561	70.679	7160	6291	4380	3408	4299	3740	MITF	melanocyte inducing transcription factor [Source:HGNC Symbol;Acc:HGNC:7105]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Human Diseases	Cancer: overview;Cancer: overview;Development and regeneration;Endocrine system;Transport and catabolism;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04380//Osteoclast differentiation;ko04916//Melanogenesis;ko04137//Mitophagy - animal;ko05218//Melanoma	K09455;K09455;K09455;K09455;K09455;K09455	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030316//osteoclast differentiation;GO:0030318//melanocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0042127//regulation of cell population proliferation;GO:0043010//camera-type eye development;GO:0043066//negative regulation of apoptotic process;GO:0043473//pigmentation;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0045165//cell fate commitment;GO:0045670//regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046849//bone remodeling;GO:0065003//protein-containing complex assembly;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:2001141//regulation of RNA biosynthetic process"	bHLH
ENSG00000187105	0.042	0.055	0.094	0	0.174	0.115	3	4	2	0	4	6	HEATR4	HEAT repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:16761]	-	-	-	-	-	GO:0005515//protein binding;GO:0016491//oxidoreductase activity	-	--
ENSG00000187109	266.37	236.638	216.283	232.786	246.947	246.231	8826	7748	5256	5480	6633	5580	NAP1L1	nucleosome assembly protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:7637]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0042470//melanosome	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0050769//positive regulation of neurogenesis;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000187116	0	0	0	0	0	0	0	0	0	0	0	0	LILRA5	leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0032396//inhibitory MHC class I receptor activity	GO:0002376//immune system process;GO:0019221//cytokine-mediated signaling pathway;GO:0032695//negative regulation of interleukin-12 production;GO:0032696//negative regulation of interleukin-13 production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032733//positive regulation of interleukin-10 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0050867//positive regulation of cell activation;GO:0051928//positive regulation of calcium ion transport;GO:0061098//positive regulation of protein tyrosine kinase activity	--
ENSG00000187118	5.382	4.454	5.661	6.472	5.777	4.454	129.8	98.3	70.48	92.1	109.51	77.65	CMC1	C-X9-C motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28783]	-	-	-	-	GO:0005739//mitochondrion	GO:0046872//metal ion binding	-	--
ENSG00000187122	0.086	0.22	0.172	0.114	0.026	0.067	11	18	9	5	2	8	SLIT1	slit guidance ligand 1 [Source:HGNC Symbol;Acc:HGNC:11085]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06838	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0048495//Roundabout binding	GO:0007097//nuclear migration;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0007420//brain development;GO:0008045//motor neuron axon guidance;GO:0016043//cellular component organization;GO:0021510//spinal cord development;GO:0021772//olfactory bulb development;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0022029//telencephalon cell migration;GO:0030154//cell differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:0033563//dorsal/ventral axon guidance;GO:0048699//generation of neurons;GO:0048812//neuron projection morphogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048846//axon extension involved in axon guidance;GO:0048853//forebrain morphogenesis;GO:0050919//negative chemotaxis;GO:0051964//negative regulation of synapse assembly	--
ENSG00000187123	1.481	1.514	1.308	1.575	1.219	2.04	120	122	79	93	81	123	LYPD6	LY6/PLAUR domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28751]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25367	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0045202//synapse	GO:0005515//protein binding;GO:0030548//acetylcholine receptor regulator activity;GO:0030550//acetylcholine receptor inhibitor activity	GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000187134	0.015	0.193	0.088	0	0.319	0.356	2	3	1	0	8	4	AKR1C1	aldo-keto reductase family 1 member C1 [Source:HGNC Symbol;Acc:HGNC:384]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Xenobiotics biodegradation and metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00140//Steroid hormone biosynthesis	K00212;K00212;K00212;K00212	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0031406//carboxylic acid binding;GO:0032052//bile acid binding;GO:0033703//3beta-hydroxy-5beta-steroid dehydrogenase activity;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047006//17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity;GO:0047023//androsterone dehydrogenase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0047042//androsterone dehydrogenase (B-specific) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047718//indanol dehydrogenase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007586//digestion;GO:0008202//steroid metabolic process;GO:0008206//bile acid metabolic process;GO:0015721//bile acid and bile salt transport;GO:0030299//intestinal cholesterol absorption;GO:0030855//epithelial cell differentiation;GO:0042448//progesterone metabolic process;GO:0042574//retinal metabolic process;GO:0042632//cholesterol homeostasis;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0046683//response to organophosphorus;GO:0071395//cellular response to jasmonic acid stimulus;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000187135	0	0.07	0	0	0	0	0	3	0	0	0	0	VSTM2B	V-set and transmembrane domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33595]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000187140	0	0	0	0	0	0	0	0	0	0	0	0	FOXD3	forkhead box D3 [Source:HGNC Symbol;Acc:HGNC:3804]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	Fork_head
ENSG00000187144	0	0	0	0	0	0	0	0	0	0	0	0	SPATA21	spermatogenesis associated 21 [Source:HGNC Symbol;Acc:HGNC:28026]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000187147	21.994	21.05	25.63	25.816	25.726	26.26	763.3	751.62	662.8	632.54	732.32	664.06	RNF220	ring finger protein 220 [Source:HGNC Symbol;Acc:HGNC:25552]	-	-	-	-	GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0003358//noradrenergic neuron development;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0021904//dorsal/ventral neural tube patterning;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051865//protein autoubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000677//regulation of transcription regulatory region DNA binding	--
ENSG00000187151	0	0	0	0	0	0	0	0	0	0	0	0	ANGPTL5	angiopoietin like 5 [Source:HGNC Symbol;Acc:HGNC:19705]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000187164	7.848	5.725	5.027	4.728	4.997	4.908	616.7	482.91	324.42	297.13	358	318.54	SHTN1	shootin 1 [Source:HGNC Symbol;Acc:HGNC:29319]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0015630//microtubule cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030424//axon;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0044295//axonal growth cone;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0042802//identical protein binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding	"GO:0006930//substrate-dependent cell migration, cell extension;GO:0007265//Ras protein signal transduction;GO:0007409//axonogenesis;GO:0032488//Cdc42 protein signal transduction;GO:0038007//netrin-activated signaling pathway;GO:0045773//positive regulation of axon extension;GO:0048812//neuron projection morphogenesis;GO:0060327//cytoplasmic actin-based contraction involved in cell motility;GO:0061163//endoplasmic reticulum polarization;GO:0061573//actin filament bundle retrograde transport;GO:2000114//regulation of establishment of cell polarity;GO:2001222//regulation of neuron migration;GO:2001224//positive regulation of neuron migration"	--
ENSG00000187166	0	0	0	0	0	0	0	0	0	0	0	0	H1-7	H1.7 linker histone [Source:HGNC Symbol;Acc:HGNC:24893]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0007283//spermatogenesis;GO:0007290//spermatid nucleus elongation;GO:0030154//cell differentiation;GO:0030261//chromosome condensation;GO:0035092//sperm chromatin condensation	--
ENSG00000187170	0	0	0	0	0	0	0	0	0	0	0	0	LCE4A	late cornified envelope 4A [Source:HGNC Symbol;Acc:HGNC:16613]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000187173	0	0	0	0	0	0	0	0	0	0	0	0	LCE2A	late cornified envelope 2A [Source:HGNC Symbol;Acc:HGNC:29469]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000187175	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP12-1	keratin associated protein 12-1 [Source:HGNC Symbol;Acc:HGNC:20529]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000187180	0	0	0	0	0	0	0	0	0	0	0	0	LCE2C	late cornified envelope 2C [Source:HGNC Symbol;Acc:HGNC:29460]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000187186	3.261	3.164	3.924	2.213	4.231	1.046	29	37	28	22	30	24	--	novel protein	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K16598;K16598;K16598	-	-	-	--
ENSG00000187187	1.811	2.424	2.505	1.431	2.057	1.652	120	108	83	66	104	86	ZNF546	zinc finger protein 546 [Source:HGNC Symbol;Acc:HGNC:28671]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000187189	19.803	21.136	19.526	21.59	20.4	19.111	1689	1812	1230	1364	1470	1186	TSPYL4	TSPY like 4 [Source:HGNC Symbol;Acc:HGNC:21559]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly	--
ENSG00000187191	0	0	0	0	0	0	0	0	0	0	0	0	DAZ3	deleted in azoospermia 3 [Source:HGNC Symbol;Acc:HGNC:15965]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000187193	5.967	4.512	6.302	5.639	4.944	7.381	50	38	39	35	35	45	MT1X	metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010038//response to metal ion;GO:0010273//detoxification of copper ion;GO:0036018//cellular response to erythropoietin;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000187210	0.343	0.276	0.143	0.226	0.302	0.278	39	32	12	19	29	23	GCNT1	glucosaminyl (N-acetyl) transferase 1 [Source:HGNC Symbol;Acc:HGNC:4203]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K00727;K00727	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna	"GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	"GO:0006486//protein glycosylation;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing;GO:0016268//O-glycan processing, core 2;GO:0032868//response to insulin;GO:0048729//tissue morphogenesis;GO:0050901//leukocyte tethering or rolling;GO:0060352//cell adhesion molecule production;GO:0060993//kidney morphogenesis"	--
ENSG00000187223	0	0	0	0	0	0	0	0	0	0	0	0	LCE2D	late cornified envelope 2D [Source:HGNC Symbol;Acc:HGNC:16518]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000187231	14.721	7.271	7.017	8.808	6.465	8.516	838	599	410	406	408	418	SESTD1	SEC14 and spectrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18379]	-	-	-	-	GO:0034704//calcium channel complex;GO:0045111//intermediate filament cytoskeleton	"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:1904878//negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	--
ENSG00000187238	0	0	0	0	0	0	0	0	0	0	0	0	LCE3B	late cornified envelope 3B [Source:HGNC Symbol;Acc:HGNC:29462]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization;GO:0031640//killing of cells of other organism;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000187239	5.32	4.768	6.237	4.041	5.24	5.07	408	372	298	252	324	273	FNBP1	formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K20121	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0005938//cell cortex;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding	GO:0006897//endocytosis;GO:0007165//signal transduction	--
ENSG00000187240	4.124	1.936	3.069	3.154	1.892	2.43	1017	491	356	272	390	388	DYNC2H1	dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10414;K10414;K10414	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0097542//ciliary tip	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0001822//kidney development;GO:0007018//microtubule-based movement;GO:0007030//Golgi organization;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0009953//dorsal/ventral pattern formation;GO:0016485//protein processing;GO:0021522//spinal cord motor neuron differentiation;GO:0030030//cell projection organization;GO:0030182//neuron differentiation;GO:0030326//embryonic limb morphogenesis;GO:0030900//forebrain development;GO:0035721//intraciliary retrograde transport;GO:0045880//positive regulation of smoothened signaling pathway;GO:0060271//cilium assembly;GO:0060976//coronary vasculature development;GO:0061512//protein localization to cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000187242	0.539	0.801	0.174	0.519	0.334	0.211	21	31	5	15	11	6	KRT12	keratin 12 [Source:HGNC Symbol;Acc:HGNC:6414]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity	GO:0002009//morphogenesis of an epithelium;GO:0007601//visual perception;GO:0008544//epidermis development;GO:0030855//epithelial cell differentiation;GO:0061303//cornea development in camera-type eye	--
ENSG00000187243	16.108	26.273	32.309	24.807	21.859	14.352	836.76	1366.59	1196.46	934.53	945.58	528.45	MAGED4B	MAGE family member D4B [Source:HGNC Symbol;Acc:HGNC:22880]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000187244	42.167	45.956	52.32	72.68	68.348	66.558	2147	2318	1920	2711	2920	2418	BCAM	basal cell adhesion molecule (Lutheran blood group) [Source:HGNC Symbol;Acc:HGNC:6722]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005055//laminin receptor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043236//laminin binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction	--
ENSG00000187257	5.733	6.055	6.292	4.004	4.775	5.092	493	467	378	245	349	307	RSBN1L	round spermatid basic protein 1 like [Source:HGNC Symbol;Acc:HGNC:24765]	-	-	-	-	GO:0005634//nucleus	GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	-	--
ENSG00000187258	0	0.056	0.095	0	0	0	0	1	2	0	0	0	NPSR1	neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:HGNC:23631]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005000//vasopressin receptor activity;GO:0008188//neuropeptide receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0042755//eating behavior;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060013//righting reflex;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1903999//negative regulation of eating behavior;GO:2000293//negative regulation of defecation	--
ENSG00000187260	2.798	2.561	3.061	5.237	4.85	3.613	107	100	81	149	162	104	WDR86	WD repeat domain 86 [Source:HGNC Symbol;Acc:HGNC:28020]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187266	3.581	3.796	3.16	3.812	4.343	4.978	166	172	114	137	174	176	EPOR	erythropoietin receptor [Source:HGNC Symbol;Acc:HGNC:3416]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Signal transduction;Signaling molecules and interaction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05079;K05079;K05079;K05079;K05079	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck	GO:0004888//transmembrane signaling receptor activity;GO:0004896//cytokine receptor activity;GO:0004900//erythropoietin receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007420//brain development;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0030097//hemopoiesis;GO:0038162//erythropoietin-mediated signaling pathway;GO:0046697//decidualization	--
ENSG00000187268	0	0	0	0	0	0	0	0	0	0	0	0	FAM9C	family with sequence similarity 9 member C [Source:HGNC Symbol;Acc:HGNC:18405]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007286//spermatid development;GO:0051321//meiotic cell cycle	--
ENSG00000187272	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-8	keratin associated protein 9-8 [Source:HGNC Symbol;Acc:HGNC:17231]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000187288	0	0	0	0	0.431	0	0	0	0	0	9	0	CIDEC	cell death inducing DFFA like effector c [Source:HGNC Symbol;Acc:HGNC:24229]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0034389//lipid droplet organization;GO:0042981//regulation of apoptotic process;GO:0097194//execution phase of apoptosis	--
ENSG00000187323	0.091	0.225	0.034	0.115	0.084	0.045	19	24	5	10	14	4	DCC	DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Development and regeneration;Cancer: specific types	ko05200//Pathways in cancer;ko04360//Axon guidance;ko05210//Colorectal cancer	K06765;K06765;K06765	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0044295//axonal growth cone;GO:0098685//Schaffer collateral - CA1 synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005042//netrin receptor activity;GO:0005515//protein binding	GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0010977//negative regulation of neuron projection development;GO:0021965//spinal cord ventral commissure morphogenesis;GO:0033563//dorsal/ventral axon guidance;GO:0033564//anterior/posterior axon guidance;GO:0038007//netrin-activated signaling pathway;GO:0048671//negative regulation of collateral sprouting;GO:0098609//cell-cell adhesion;GO:0099170//postsynaptic modulation of chemical synaptic transmission;GO:1901214//regulation of neuron death;GO:2000171//negative regulation of dendrite development	--
ENSG00000187325	13.863	12.221	11.228	8.525	9.321	10.499	764	677	457	348	434	421	TAF9B	TATA-box binding protein associated factor 9b [Source:HGNC Symbol;Acc:HGNC:17306]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03133	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator"	--
ENSG00000187372	0.327	0.629	0.604	0.593	0.421	0.522	34.29	66.32	46.84	46.11	37.37	39.9	PCDHB13	protocadherin beta 13 [Source:HGNC Symbol;Acc:HGNC:8684]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032391//photoreceptor connecting cilium;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097381//photoreceptor disc membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000187391	2.822	2.842	2.483	2.371	2.368	2.27	387	383	201	239	261	214	MAGI2	"membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]"	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04015//Rap1 signaling pathway	K05629;K05629	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0036057//slit diaphragm;GO:0043005//neuron projection;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019902//phosphatase binding;GO:0030159//signaling receptor complex adaptor activity;GO:0031697//beta-1 adrenergic receptor binding;GO:0046332//SMAD binding;GO:0060090//molecular adaptor activity;GO:0070699//type II activin receptor binding	GO:0002092//positive regulation of receptor internalization;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0010976//positive regulation of neuron projection development;GO:0016310//phosphorylation;GO:0030336//negative regulation of cell migration;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0038180//nerve growth factor signaling pathway;GO:0043113//receptor clustering;GO:0051898//negative regulation of protein kinase B signaling;GO:0060395//SMAD protein signal transduction;GO:0072015//glomerular visceral epithelial cell development;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000187398	0.159	0.096	0.175	0.052	0.057	0.114	14	10	5	4	5	9	LUZP2	leucine zipper protein 2 [Source:HGNC Symbol;Acc:HGNC:23206]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000187416	0.016	0.016	0	0	0	0.044	1	1	0	0	0	2	LHFPL3	LHFPL tetraspan subfamily member 3 [Source:HGNC Symbol;Acc:HGNC:6589]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007605//sensory perception of sound	--
ENSG00000187446	30.639	29.415	28.388	34.547	34.327	38.508	1555	1480	1077	1268	1466.5	1217	CHP1	calcineurin like EF-hand protein 1 [Source:HGNC Symbol;Acc:HGNC:17433]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0070062//extracellular exosome	GO:0004860//protein kinase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015459//potassium channel regulator activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0001578//microtubule bundle formation;GO:0001933//negative regulation of protein phosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0006611//protein export from nucleus;GO:0006813//potassium ion transport;GO:0007264//small GTPase mediated signal transduction;GO:0010923//negative regulation of phosphatase activity;GO:0015031//protein transport;GO:0022406//membrane docking;GO:0031122//cytoplasmic microtubule organization;GO:0031397//negative regulation of protein ubiquitination;GO:0031953//negative regulation of protein autophosphorylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0042308//negative regulation of protein import into nucleus;GO:0050821//protein stabilization;GO:0051222//positive regulation of protein transport;GO:0051453//regulation of intracellular pH;GO:0060050//positive regulation of protein glycosylation;GO:0061024//membrane organization;GO:0061025//membrane fusion;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0071468//cellular response to acidic pH;GO:0090314//positive regulation of protein targeting to membrane;GO:1901214//regulation of neuron death	--
ENSG00000187474	0.055	0.037	0	0.117	0.087	0	3	2	0	4	4	0	FPR3	formyl peptide receptor 3 [Source:HGNC Symbol;Acc:HGNC:3828]	Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Infectious disease: bacterial	ko04080//Neuroactive ligand-receptor interaction;ko04613//Neutrophil extracellular trap formation;ko05150//Staphylococcus aureus infection	K04173;K04173;K04173	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004982//N-formyl peptide receptor activity;GO:0005515//protein binding	GO:0002430//complement receptor mediated signaling pathway;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration	--
ENSG00000187475	0	0	0	0	0	0	0	0	0	0	0	0	H1-6	"H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720]"	-	-	-	-	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0031492//nucleosomal DNA binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0016584//nucleosome positioning;GO:0030154//cell differentiation;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination	--
ENSG00000187479	0.155	0.154	0.053	0	0.092	0	4	4	1	0	2	0	C11orf96	chromosome 11 open reading frame 96 [Source:HGNC Symbol;Acc:HGNC:38675]	-	-	-	-	-	-	-	--
ENSG00000187486	0.901	0.815	1.206	0.576	1.216	1.047	44	58	62	25	53	50	KCNJ11	potassium inwardly rectifying channel subfamily J member 11 [Source:HGNC Symbol;Acc:HGNC:6257]	Organismal Systems;Organismal Systems;Human Diseases	Endocrine system;Endocrine system;Endocrine and metabolic disease	ko04911//Insulin secretion;ko04929//GnRH secretion;ko04930//Type II diabetes mellitus	K05004;K05004;K05004	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008282//inward rectifying potassium channel;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0030506//ankyrin binding;GO:0030955//potassium ion binding;GO:0044325//transmembrane transporter binding	GO:0006006//glucose metabolic process;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0009410//response to xenobiotic stimulus;GO:0033198//response to ATP;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0046676//negative regulation of insulin secretion;GO:0050796//regulation of insulin secretion;GO:0050877//nervous system process;GO:0071805//potassium ion transmembrane transport;GO:0098662//inorganic cation transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000187492	0.095	0.019	0.064	0	0.045	0.079	5	1	1	0	2	3	CDHR4	cadherin related family member 4 [Source:HGNC Symbol;Acc:HGNC:34527]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000187498	93.084	100.131	55.298	46.159	58.73	43.9	12601	13643	5536	4576	6721	4323	COL4A1	collagen type IV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2202]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0048407//platelet-derived growth factor binding	GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0007420//brain development;GO:0007528//neuromuscular junction development;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030855//epithelial cell differentiation;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0061304//retinal blood vessel morphogenesis;GO:0061333//renal tubule morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0071711//basement membrane organization	--
ENSG00000187510	0	0.024	0	0	0	0.033	0	2	0	0	0	2	PLEKHG7	pleckstrin homology and RhoGEF domain containing G7 [Source:HGNC Symbol;Acc:HGNC:33829]	-	-	-	-	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000187513	0.821	0.77	0.403	4.778	4.841	5.85	25	25	10	104	134	138	GJA4	gap junction protein alpha 4 [Source:HGNC Symbol;Acc:HGNC:4278]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0005515//protein binding	GO:0001568//blood vessel development;GO:0003158//endothelium development;GO:0006816//calcium ion transport;GO:0007043//cell-cell junction assembly;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0048265//response to pain;GO:0055085//transmembrane transport	--
ENSG00000187514	619.507	613.623	585.689	601.786	572.847	573.894	15603	15534	10897	11230	12192	10519	PTMA	prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042393//histone binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000187516	0	0	0	0	0	0	0	0	0	0	0	0	H2AP	H2A.P histone [Source:HGNC Symbol;Acc:HGNC:18417]	-	-	-	-	GO:0000786//nucleosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000187522	3.658	3.747	3.876	3.218	3.259	4.274	125.91	124.94	93.48	87.13	88.78	102.56	HSPA14	heat shock protein family A (Hsp70) member 14 [Source:HGNC Symbol;Acc:HGNC:29526]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031072//heat shock protein binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0016192//vesicle-mediated transport;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0051083//'de novo' cotranslational protein folding;GO:0051085//chaperone cofactor-dependent protein refolding	--
ENSG00000187527	0.024	0.073	0.033	0	0.014	0.034	2	6	2	0	1	2	ATP13A5	ATPase 13A5 [Source:HGNC Symbol;Acc:HGNC:31789]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019829//ATPase-coupled cation transmembrane transporter activity;GO:0046872//metal ion binding	GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000187531	4.248	4.671	4.919	5.094	4.135	5.454	152	168	130	135	125	142	SIRT7	sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K11417;K11417	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005731//nucleolus organizer region;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0035861//site of double-strand break	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019213//deacetylase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0036055//protein-succinyllysine desuccinylase activity;GO:0046872//metal ion binding;GO:0061697//protein-glutaryllysine deglutarylase activity;GO:0070403//NAD+ binding;GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0106231//protein-propionyllysine depropionylase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001649//osteoblast differentiation;GO:0006111//regulation of gluconeogenesis;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006476//protein deacetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007072//positive regulation of transcription involved in exit from mitosis;GO:0007129//homologous chromosome pairing at meiosis;GO:0009303//rRNA transcription;GO:0010529//negative regulation of transposition;GO:0010821//regulation of mitochondrion organization;GO:0016570//histone modification;GO:0031397//negative regulation of protein ubiquitination;GO:0036049//peptidyl-lysine desuccinylation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046825//regulation of protein export from nucleus;GO:0061698//protein deglutarylation;GO:0061699//peptidyl-lysine deglutarylation;GO:0062176//R-loop disassembly;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0106230//protein depropionylation;GO:1901836//regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1990258//histone glutamine methylation;GO:2000234//positive regulation of rRNA processing;GO:2001032//regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000187533	0	0	0	0	0	0	0	0	0	0	0	0	PRR27	proline rich 27 [Source:HGNC Symbol;Acc:HGNC:33193]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	-	-	--
ENSG00000187535	14.183	13.504	17.587	13.388	12.649	11.79	1303	1334	1155	975	1019	929	IFT140	intraflagellar transport 140 [Source:HGNC Symbol;Acc:HGNC:29077]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0030991//intraciliary transport particle A;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097730//non-motile cilium	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008589//regulation of smoothened signaling pathway;GO:0021532//neural tube patterning;GO:0030030//cell projection organization;GO:0031076//embryonic camera-type eye development;GO:0035108//limb morphogenesis;GO:0035721//intraciliary retrograde transport;GO:0035845//photoreceptor cell outer segment organization;GO:0042073//intraciliary transport;GO:0042733//embryonic digit morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0060271//cilium assembly;GO:0061512//protein localization to cilium;GO:1902017//regulation of cilium assembly;GO:1905515//non-motile cilium assembly;GO:1990403//embryonic brain development	--
ENSG00000187537	0	0	0	0	0	0	0	0	0	0	0	0	POTEG	POTE ankyrin domain family member G [Source:HGNC Symbol;Acc:HGNC:33896]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187545	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF10	PRAME family member 10 [Source:HGNC Symbol;Acc:HGNC:27997]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000187546	0	0	0	0	0	0	0	0	0	0	0	0	AGMO	alkylglycerol monooxygenase [Source:HGNC Symbol;Acc:HGNC:33784]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050479//glyceryl-ether monooxygenase activity	GO:0006629//lipid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0008610//lipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0046485//ether lipid metabolic process	--
ENSG00000187550	0.021	0.091	0	0.134	0.051	0.154	1	2	0	3	2	4	SBK2	SH3 domain binding kinase family member 2 [Source:HGNC Symbol;Acc:HGNC:34416]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000187553	0	0.045	0	0	0	0	0	3	0	0	0	0	CYP26C1	cytochrome P450 family 26 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:20577]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K12665;K12665	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0001972//retinoic acid binding;GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006766//vitamin metabolic process;GO:0007417//central nervous system development;GO:0009952//anterior/posterior pattern specification;GO:0014032//neural crest cell development;GO:0016125//sterol metabolic process;GO:0034653//retinoic acid catabolic process;GO:0048284//organelle fusion;GO:0048387//negative regulation of retinoic acid receptor signaling pathway	--
ENSG00000187554	5.443	4.804	6.835	5.593	5.563	7.183	401	356	323	327	358	382	TLR5	toll like receptor 5 [Source:HGNC Symbol;Acc:HGNC:11851]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Immune disease;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04620//Toll-like receptor signaling pathway;ko05321//Inflammatory bowel disease;ko05134//Legionellosis	K10168;K10168;K10168;K10168;K10168;K10168	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001817//regulation of cytokine production;GO:0001819//positive regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0008584//male gonad development;GO:0032757//positive regulation of interleukin-8 production;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000187555	26.677	25.902	25.624	26.08	24.644	23.852	2306	2298	1649	1576	1819	1525	USP7	ubiquitin specific peptidase 7 [Source:HGNC Symbol;Acc:HGNC:12630]	Human Diseases;Human Diseases;Environmental Information Processing	Infectious disease: viral;Cancer: overview;Signal transduction	ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko04068//FoxO signaling pathway	K11838;K11838;K11838	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016605//PML body;GO:0032991//protein-containing complex	GO:0002039//p53 binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0101005//deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	"GO:0006111//regulation of gluconeogenesis;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010216//maintenance of DNA methylation;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0031647//regulation of protein stability;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035520//monoubiquitinated protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0050821//protein stabilization;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:1901537//positive regulation of DNA demethylation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904353//regulation of telomere capping;GO:1905279//regulation of retrograde transport, endosome to Golgi"	--
ENSG00000187556	0.203	0.051	0.34	0.343	0.241	0	4	1	4	5	4	0	NANOS3	nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:22048]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006417//regulation of translation;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0048477//oogenesis;GO:0051726//regulation of cell cycle;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000187559	0	0	0	0	0	0	0	0	0	0	0	0	FOXD4L3	forkhead box D4 like 3 [Source:HGNC Symbol;Acc:HGNC:18523]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000187566	0.905	1.286	0.758	1.018	0.765	0.799	42	60	26	35	30	27	NHLRC1	NHL repeat containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21576]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10602	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0001932//regulation of protein phosphorylation;GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006914//autophagy;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0031396//regulation of protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0034976//response to endoplasmic reticulum stress;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0045859//regulation of protein kinase activity;GO:1903076//regulation of protein localization to plasma membrane	--
ENSG00000187569	0	0	0	0.059	0	0	0	0	0	1	0	0	DPPA3	developmental pluripotency associated 3 [Source:HGNC Symbol;Acc:HGNC:19199]	-	-	-	-	GO:0001939//female pronucleus;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0035064//methylated histone binding	GO:0006325//chromatin organization;GO:0044726//protection of DNA demethylation of female pronucleus;GO:1901536//negative regulation of DNA demethylation;GO:2000653//regulation of genetic imprinting	--
ENSG00000187581	0	0	0	0	0.105	0	0	0	0	0	1	0	COX8C	cytochrome c oxidase subunit 8C [Source:HGNC Symbol;Acc:HGNC:24382]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045277//respiratory chain complex IV	-	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen"	--
ENSG00000187583	0	0.06	0.06	0	0.07	0.124	0	4	2	0	3	2	PLEKHN1	pleckstrin homology domain containing N1 [Source:HGNC Symbol;Acc:HGNC:25284]	-	-	-	-	GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0001786//phosphatidylserine binding;GO:0005515//protein binding;GO:0070300//phosphatidic acid binding;GO:1901612//cardiolipin binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0001666//response to hypoxia;GO:0043065//positive regulation of apoptotic process;GO:0061158//3'-UTR-mediated mRNA destabilization	--
ENSG00000187595	0.097	0.097	0.098	0.131	0.101	0.167	4	5	3	4	4	5	ZNF385C	zinc finger protein 385C [Source:HGNC Symbol;Acc:HGNC:33722]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000187601	50.823	51.629	49.547	44.521	42.719	47.717	1518	1550	1093	985	1078	1037	MAGEH1	MAGE family member H1 [Source:HGNC Symbol;Acc:HGNC:24092]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process	--
ENSG00000187605	4.499	4.033	4.672	4.193	4.712	4.593	1071	1014	832	777	969	836	TET3	tet methylcytosine dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:28313]	-	-	-	-	GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0070579//methylcytosine dioxygenase activity	GO:0006211//5-methylcytosine catabolic process;GO:0006325//chromatin organization;GO:0006493//protein O-linked glycosylation;GO:0006807//nitrogen compound metabolic process;GO:0043412//macromolecule modification;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0044727//DNA demethylation of male pronucleus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation;GO:0080182//histone H3-K4 trimethylation	--
ENSG00000187607	9.62	6.569	7.554	6.967	8.139	7.859	535.24	456.9	330.66	263.3	310.68	340.77	ZNF286A	zinc finger protein 286A [Source:HGNC Symbol;Acc:HGNC:13501]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000187608	5.671	7.906	6.456	8.072	5.196	9.882	75	105	63	79	58	95	ISG15	ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system	ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04622//RIG-I-like receptor signaling pathway	K12159;K12159;K12159;K12159	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding	GO:0002376//immune system process;GO:0007229//integrin-mediated signaling pathway;GO:0009615//response to virus;GO:0009617//response to bacterium;GO:0019941//modification-dependent protein catabolic process;GO:0030501//positive regulation of bone mineralization;GO:0031397//negative regulation of protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0032461//positive regulation of protein oligomerization;GO:0032649//regulation of interferon-gamma production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0034340//response to type I interferon;GO:0042742//defense response to bacterium;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045648//positive regulation of erythrocyte differentiation;GO:0051607//defense response to virus;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0070585//protein localization to mitochondrion	--
ENSG00000187609	3.497	3.399	4.886	4.142	4.696	4.498	125	126	119	120	131	118	EXD3	exonuclease 3'-5' domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26023]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006139//nucleobase-containing compound metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000187612	0	0	0	0	0	0	0	0	0	0	0	0	OR5W2	olfactory receptor family 5 subfamily W member 2 [Source:HGNC Symbol;Acc:HGNC:15299]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187616	0.116	0.289	0	0.392	0.069	0.159	2	5	0	5	1	2	MYMK	"myomaker, myoblast fusion factor [Source:HGNC Symbol;Acc:HGNC:33778]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	-	GO:0007517//muscle organ development;GO:0007520//myoblast fusion;GO:0014905//myoblast fusion involved in skeletal muscle regeneration;GO:0043403//skeletal muscle tissue regeneration;GO:0045026//plasma membrane fusion;GO:1904206//positive regulation of skeletal muscle hypertrophy	--
ENSG00000187624	5.787	5.714	5.565	6.296	6.912	5.682	221	210	148	167	223	149	C17orf97	chromosome 17 open reading frame 97 [Source:HGNC Symbol;Acc:HGNC:33800]	-	-	-	-	-	GO:0005515//protein binding	GO:0016598//protein arginylation	--
ENSG00000187626	2.047	2.061	2.206	1.826	1.868	1.896	227	229.74	180.67	150	175	153	ZKSCAN4	zinc finger with KRAB and SCAN domains 4 [Source:HGNC Symbol;Acc:HGNC:13854]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000187627	0	0	0	0.01	0.014	0	0	0	0	1	1.66	0	RGPD1	RANBP2 like and GRIP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:32414]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000187630	4.726	4.294	6.847	6.375	5.336	6.015	112.35	103.4	122	111.03	104.81	104.32	DHRS4L2	dehydrogenase/reductase 4 like 2 [Source:HGNC Symbol;Acc:HGNC:19731]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11148;K11148	GO:0005576//extracellular region;GO:0005777//peroxisome	GO:0004090//carbonyl reductase (NADPH) activity;GO:0016491//oxidoreductase activity	GO:0042574//retinal metabolic process	--
ENSG00000187634	4.989	5.421	17.558	4.361	6.851	6.599	259.2	270.69	264.93	172	297.9	195.18	SAMD11	sterile alpha motif domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28706]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	SAND
ENSG00000187642	0	0.019	0.026	0.021	0.056	0	0	1	1	1	3	0	PERM1	"PPARGC1 and ESRR induced regulator, muscle 1 [Source:HGNC Symbol;Acc:HGNC:28208]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	"GO:0006355//regulation of transcription, DNA-templated;GO:0014850//response to muscle activity"	--
ENSG00000187650	1.507	1.342	1.515	1.976	1.541	1.361	70	62.65	52	68	60.5	46	VMAC	vimentin type intermediate filament associated coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:33803]	-	-	-	-	GO:0005737//cytoplasm;GO:0045098//type III intermediate filament	GO:0005515//protein binding	-	--
ENSG00000187658	0	0	0	0	0	0	0	0	0	0	0	0	C5orf52	chromosome 5 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:35121]	-	-	-	-	-	-	-	--
ENSG00000187664	0.333	0.309	0.21	0.225	0.184	0.076	30	28	14	15	14	5	HAPLN4	hyaluronan and proteoglycan link protein 4 [Source:HGNC Symbol;Acc:HGNC:31357]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0005540//hyaluronic acid binding	GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0007417//central nervous system development	--
ENSG00000187672	2.051	2.342	2.002	1.009	1.067	0.978	205	227	138	76	104	84	ERC2	ELKS/RAB6-interacting/CAST family member 2 [Source:HGNC Symbol;Acc:HGNC:31922]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0030426//growth cone;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0048788//cytoskeleton of presynaptic active zone;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0098882//structural constituent of presynaptic active zone	GO:0007274//neuromuscular synaptic transmission;GO:0016082//synaptic vesicle priming;GO:0048167//regulation of synaptic plasticity;GO:0048790//maintenance of presynaptic active zone structure	--
ENSG00000187676	4.244	3.55	4.785	3.335	2.965	4.543	371	312	309	216	219	289	B3GLCT	beta 3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:20207]	Metabolism	Glycan biosynthesis and metabolism	ko00514//Other types of O-glycan biosynthesis	K13675	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008375//acetylglucosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006004//fucose metabolic process;GO:0006486//protein glycosylation;GO:0036066//protein O-linked fucosylation	--
ENSG00000187678	1.096	0.655	0.586	0.677	0.78	0.895	77	67	44	51	67	49	SPRY4	sprouty RTK signaling antagonist 4 [Source:HGNC Symbol;Acc:HGNC:15533]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042995//cell projection	GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding	GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048513//animal organ development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1990830//cellular response to leukemia inhibitory factor	--
ENSG00000187682	0	0	0	0	0.069	0.052	0	0	0	0	1	1	ERAS	ES cell expressed Ras [Source:HGNC Symbol;Acc:HGNC:5174]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding	GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction	--
ENSG00000187688	0.355	0.304	0.421	0.07	0.062	0.024	14	7	7	3	3	1	TRPV2	transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082]	Organismal Systems;Organismal Systems	Immune system;Sensory system	ko04621//NOD-like receptor signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels	K04971;K04971	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0032584//growth cone membrane;GO:0042470//melanosome;GO:0044295//axonal growth cone;GO:0044297//cell body	GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015075//ion transmembrane transporter activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007600//sensory perception;GO:0009266//response to temperature stimulus;GO:0009408//response to heat;GO:0045773//positive regulation of axon extension;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0090280//positive regulation of calcium ion import;GO:0098703//calcium ion import across plasma membrane;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000187689	0	0	0.086	0	0	0	0	0	1	0	0	0	AMTN	amelotin [Source:HGNC Symbol;Acc:HGNC:33188]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005911//cell-cell junction;GO:0031012//extracellular matrix	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0031214//biomineral tissue development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0070169//positive regulation of biomineral tissue development;GO:0070175//positive regulation of enamel mineralization	--
ENSG00000187690	0.051	0.076	0	0	0.09	0	2	3	0	0	3	0	EZHIP	EZH inhibitory protein [Source:HGNC Symbol;Acc:HGNC:33738]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0061086//negative regulation of histone H3-K27 methylation;GO:1902465//negative regulation of histone H3-K27 trimethylation	--
ENSG00000187699	0.394	0.408	0.49	0.394	0.469	0.525	33	28	24	22	25	32	C2orf88	chromosome 2 open reading frame 88 [Source:HGNC Symbol;Acc:HGNC:28191]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding	-	--
ENSG00000187701	0	0	0	0	0	0	0	0	0	0	0	0	OR2T27	olfactory receptor family 2 subfamily T member 27 [Source:HGNC Symbol;Acc:HGNC:31252]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187713	14.091	15.856	17.205	18.442	15.295	17.887	458	518	413	444	420	423	TMEM203	transmembrane protein 203 [Source:HGNC Symbol;Acc:HGNC:28217]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006874//cellular calcium ion homeostasis;GO:0007283//spermatogenesis	--
ENSG00000187714	3.579	4.635	2.004	1.971	2.201	0.715	179	233	74	73	93	26	SLC18A3	solute carrier family 18 member A3 [Source:HGNC Symbol;Acc:HGNC:10936]	Organismal Systems;Organismal Systems	Nervous system;Nervous system	ko04725//Cholinergic synapse;ko04721//Synaptic vesicle cycle	K14636;K14636	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030121//AP-1 adaptor complex;GO:0030122//AP-2 adaptor complex;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0043195//terminal bouton;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane	GO:0005277//acetylcholine transmembrane transporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006836//neurotransmitter transport;GO:0007268//chemical synaptic transmission;GO:0015695//organic cation transport;GO:0055085//transmembrane transport;GO:1901374//acetate ester transport	--
ENSG00000187715	0.055	0.05	0.124	0.08	0.11	0.069	6	6	10	7	11	6	KBTBD12	kelch repeat and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25731]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187720	0.376	0.184	0.651	0.379	0.315	0.391	58	36	32	34	31	49	THSD4	thrombospondin type 1 domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25835]	Environmental Information Processing	Signal transduction	ko04350//TGF-beta signaling pathway	K23377	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0016787//hydrolase activity	GO:0048251//elastic fiber assembly	--
ENSG00000187726	0.335	0.362	0.696	0.112	0.236	0.256	6	6	9	2	5	3	DNAJB13	DnaJ heat shock protein family (Hsp40) member B13 [Source:HGNC Symbol;Acc:HGNC:30718]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097224//sperm connecting piece	GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0030030//cell projection organization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:1904158//axonemal central apparatus assembly	--
ENSG00000187730	1.826	1.944	1.887	2.783	3.665	2.237	58	74	54	80	117	63	GABRD	gamma-aminobutyric acid type A receptor subunit delta [Source:HGNC Symbol;Acc:HGNC:4084]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05184;K05184;K05184;K05184;K05184	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:1902476//chloride transmembrane transport	--
ENSG00000187733	0	0	0	0	0	0	0	0	0	0	0	0	AMY1C	amylase alpha 1C [Source:HGNC Symbol;Acc:HGNC:476]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism	K01176;K01176;K01176;K01176;K01176	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004556//alpha-amylase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0031404//chloride ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0103025//alpha-amylase activity (releasing maltohexaose)"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016052//carbohydrate catabolic process;GO:0044245//polysaccharide digestion	--
ENSG00000187735	41.177	36.846	39.062	28.21	32.777	32.12	2291	2020	1503	1203	1435	1266	TCEA1	transcription elongation factor A1 [Source:HGNC Symbol;Acc:HGNC:11612]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006414//translational elongation;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000187736	3.162	2.561	3.434	3.51	4.495	3.625	207	154	127	162	189	135	NHEJ1	non-homologous end joining factor 1 [Source:HGNC Symbol;Acc:HGNC:25737]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K10980	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0032807//DNA ligase IV complex;GO:0035861//site of double-strand break;GO:0070419//nonhomologous end joining complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045027//DNA end binding;GO:0070182//DNA polymerase binding	GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0007417//central nervous system development;GO:0010212//response to ionizing radiation;GO:0030183//B cell differentiation;GO:0030217//T cell differentiation;GO:0033152//immunoglobulin V(D)J recombination;GO:0051103//DNA ligation involved in DNA repair;GO:0051351//positive regulation of ligase activity	--
ENSG00000187741	2.067	1.266	1.719	1.868	1.98	1.615	90.02	78.82	54.69	45.75	90.99	61.82	FANCA	FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10888	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043240//Fanconi anaemia nuclear complex	GO:0005515//protein binding	GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007140//male meiotic nuclear division;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0036297//interstrand cross-link repair;GO:0042127//regulation of cell population proliferation;GO:0045589//regulation of regulatory T cell differentiation;GO:0050727//regulation of inflammatory response;GO:0051090//regulation of DNA-binding transcription factor activity;GO:0065003//protein-containing complex assembly;GO:2000348//regulation of CD40 signaling pathway	--
ENSG00000187742	10.31	11.399	9.483	9.657	10.288	10.347	625	621	434	406	468	436	SECISBP2	SECIS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30972]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0035368//selenocysteine insertion sequence binding;GO:0043021//ribonucleoprotein complex binding	"GO:0001514//selenocysteine incorporation;GO:0006412//translation;GO:0021756//striatum development;GO:0048666//neuron development;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000187747	0	0	0	0	0	0	0	0	0	0	0	0	OR52B6	olfactory receptor family 52 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:15211]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187753	0	0	0	0	0	0	0	0	0	0	0	0	C9orf153	chromosome 9 open reading frame 153 [Source:HGNC Symbol;Acc:HGNC:31456]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187754	0	0	0	0	0	0	0	0	0	0	0	0	SSX7	SSX family member 7 [Source:HGNC Symbol;Acc:HGNC:19653]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000187758	0	0	0	0	0	0	0	0	0	0	0	0	ADH1A	"alcohol dehydrogenase 1A (class I), alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:249]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004745//NAD-retinol dehydrogenase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0046872//metal ion binding"	GO:0006066//alcohol metabolic process;GO:0006069//ethanol oxidation;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process	--
ENSG00000187764	3.23	3.729	4.466	3.044	4.923	4.341	294	339	281	208	294	270	SEMA4D	semaphorin 4D [Source:HGNC Symbol;Acc:HGNC:10732]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0045499//chemorepellent activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007162//negative regulation of cell adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0031344//regulation of cell projection organization;GO:0043066//negative regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0043931//ossification involved in bone maturation;GO:0045668//negative regulation of osteoblast differentiation;GO:0048672//positive regulation of collateral sprouting;GO:0048814//regulation of dendrite morphogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0050772//positive regulation of axonogenesis;GO:0050919//negative chemotaxis;GO:0070486//leukocyte aggregation;GO:0071526//semaphorin-plexin signaling pathway;GO:1900220//semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis;GO:1905704//positive regulation of inhibitory synapse assembly	--
ENSG00000187766	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-8	keratin associated protein 10-8 [Source:HGNC Symbol;Acc:HGNC:20525]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000187772	0.239	0.261	0.144	0.195	0.239	0.049	27	25	12	13	13	4	LIN28B	lin-28 homolog B [Source:HGNC Symbol;Acc:HGNC:32207]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding	GO:0010587//miRNA catabolic process;GO:0010629//negative regulation of gene expression;GO:0031047//gene silencing by RNA;GO:0031054//pre-miRNA processing;GO:0031123//RNA 3'-end processing;GO:0050779//RNA destabilization;GO:2000627//positive regulation of miRNA catabolic process;GO:2000632//negative regulation of pre-miRNA processing;GO:2000635//negative regulation of primary miRNA processing	CSD
ENSG00000187773	0	0.072	0.086	0.043	0	0.108	0	2	4	2	0	3	DIPK1C	divergent protein kinase domain 1C [Source:HGNC Symbol;Acc:HGNC:31729]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000187775	0.037	0.018	0.038	0.075	0.077	0.102	4	2	3	6	7	8	DNAH17	dynein axonemal heavy chain 17 [Source:HGNC Symbol;Acc:HGNC:2946]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0036158//outer dynein arm assembly;GO:0060285//cilium-dependent cell motility	--
ENSG00000187778	22.69	20.254	25.569	25.189	21.518	23.047	856	804	750	742	718	632	MCRS1	microspherule protein 1 [Source:HGNC Symbol;Acc:HGNC:6960]	-	-	-	-	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005844//polysome;GO:0030425//dendrite;GO:0031011//Ino80 complex;GO:0043204//perikaryon;GO:0044545//NSL complex;GO:0071339//MLL1 complex	GO:0002151//G-quadruplex RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0010521//telomerase inhibitor activity;GO:0034046//poly(G) binding	"GO:0000723//telomere maintenance;GO:0006275//regulation of DNA replication;GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006310//DNA recombination;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006464//cellular protein modification process;GO:0006974//cellular response to DNA damage stimulus;GO:0033044//regulation of chromosome organization;GO:0042766//nucleosome mobilization;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0045739//positive regulation of DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045995//regulation of embryonic development;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051726//regulation of cell cycle;GO:0051974//negative regulation of telomerase activity;GO:0060382//regulation of DNA strand elongation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904507//positive regulation of telomere maintenance in response to DNA damage;GO:1904751//positive regulation of protein localization to nucleolus"	--
ENSG00000187783	13.334	14.538	15.898	7.744	8.041	7.812	766	817	659	322	381	321	TMEM72	transmembrane protein 72 [Source:HGNC Symbol;Acc:HGNC:31658]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000187790	0.89	0.584	0.545	0.121	0.647	0.535	89	59	37	10	40	27	FANCM	FA complementation group M [Source:HGNC Symbol;Acc:HGNC:23168]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10896	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex	GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0043138//3'-5' DNA helicase activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0032508//DNA duplex unwinding;GO:0036297//interstrand cross-link repair;GO:0045003//double-strand break repair via synthesis-dependent strand annealing;GO:0071932//replication fork reversal;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1902527//positive regulation of protein monoubiquitination	--
ENSG00000187791	0	0	0	0	0	0	0	0	0	0	0	0	FAM205C	family with sequence similarity 205 member C [Source:HGNC Symbol;Acc:HGNC:42673]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000187792	1.924	2.156	2.135	1.594	1.694	1.594	277	312	227	170	206	167	ZNF70	zinc finger protein 70 [Source:HGNC Symbol;Acc:HGNC:13140]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043076//megasporocyte nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000187796	0.05	0	0	0	0	0	2	0	0	0	0	0	CARD9	caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05152//Tuberculosis;ko04621//NOD-like receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway	K12794;K12794;K12794;K12794	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0046872//metal ion binding;GO:0050700//CARD domain binding	GO:0001819//positive regulation of cytokine production;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002446//neutrophil mediated immunity;GO:0016064//immunoglobulin mediated immune response;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032740//positive regulation of interleukin-17 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0048874//host-mediated regulation of intestinal microbiota composition;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization;GO:0061760//antifungal innate immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:2000318//positive regulation of T-helper 17 type immune response	--
ENSG00000187800	0.356	0.347	0.174	0.118	0.152	0.285	36	36	13	9	13	21	PEAR1	platelet endothelial aggregation receptor 1 [Source:HGNC Symbol;Acc:HGNC:33631]	-	-	-	-	GO:0001891//phagocytic cup;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0043491//protein kinase B signaling;GO:0043654//recognition of apoptotic cell;GO:0070527//platelet aggregation	--
ENSG00000187801	1.082	0.85	0.836	0.339	0.888	0.658	47	35	27	11	31	20	ZFP69B	ZFP69 zinc finger protein B [Source:HGNC Symbol;Acc:HGNC:28053]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005730//nucleolus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007030//Golgi organization"	zf-C2H2
ENSG00000187806	0	0	0	0	0	0	0	0	0	0	0	0	TMEM202	transmembrane protein 202 [Source:HGNC Symbol;Acc:HGNC:33733]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000187808	0.03	0.148	0.04	0.161	0	0.205	1	5	1	4	0	5	SOWAHD	sosondowah ankyrin repeat domain family member D [Source:HGNC Symbol;Acc:HGNC:32960]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187815	0.881	1.284	0.77	1.09	1.012	0.853	48	68	33	44	41	36	ZFP69	ZFP69 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:24708]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0019216//regulation of lipid metabolic process"	zf-C2H2
ENSG00000187821	0	0	0	0.077	0	0	0	0	0	1	0	0	HELT	helt bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:33783]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001967//suckling behavior;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0009791//post-embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0010259//multicellular organism aging;GO:0010467//gene expression;GO:0021858//GABAergic neuron differentiation in basal ganglia;GO:0030182//neuron differentiation;GO:0035264//multicellular organism growth;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis"	bHLH
ENSG00000187823	0	0	0	0	0	0	0	0	0	0	0	0	RTL4	retrotransposon Gag like 4 [Source:HGNC Symbol;Acc:HGNC:25214]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0042415//norepinephrine metabolic process;GO:0050890//cognition	--
ENSG00000187824	1.388	0.84	1.067	0.902	2.121	1.453	71	43	46	39	57	52	TMEM220	transmembrane protein 220 [Source:HGNC Symbol;Acc:HGNC:33757]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000187833	0	0	0	0	0	0	0	0	0	0	0	0	C2orf78	chromosome 2 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:34349]	-	-	-	-	-	-	-	--
ENSG00000187837	6.397	5.84	5.983	7.568	5.777	6.617	97	89	67	85	74	73	H1-2	"H1.2 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4716]"	-	-	-	-	GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0035327//transcriptionally active chromatin	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006334//nucleosome assembly;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0045910//negative regulation of DNA recombination;GO:0080182//histone H3-K4 trimethylation;GO:0098532//histone H3-K27 trimethylation	--
ENSG00000187838	16.181	16.573	14.454	16.423	15.229	14.3	543.18	542	358	424.25	431	360	PLSCR3	phospholipid scramblase 3 [Source:HGNC Symbol;Acc:HGNC:16495]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0017128//phospholipid scramblase activity;GO:0032791//lead ion binding;GO:0043621//protein self-association;GO:0045340//mercury ion binding;GO:0048306//calcium-dependent protein binding	GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0017121//plasma membrane phospholipid scrambling;GO:0032049//cardiolipin biosynthetic process;GO:0042593//glucose homeostasis;GO:0042632//cholesterol homeostasis;GO:0042981//regulation of apoptotic process;GO:0071222//cellular response to lipopolysaccharide;GO:0090199//regulation of release of cytochrome c from mitochondria	--
ENSG00000187840	18.83	16.298	14.366	21.171	16.906	26.921	323	281	182	269	245	336	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3288]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases	Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Signal transduction;Cell growth and death;Endocrine system;Signal transduction;Signal transduction;Cancer: overview;Aging;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05163//Human cytomegalovirus infection;ko05207//Chemical carcinogenesis - receptor activation;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko05231//Choline metabolism in cancer;ko04211//Longevity regulating pathway;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05221//Acute myeloid leukemia	K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205;K07205	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0030371//translation repressor activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0031929//TOR signaling;GO:0045931//positive regulation of mitotic cell cycle;GO:0045947//negative regulation of translational initiation	--
ENSG00000187848	0	0	0.229	0.069	0	0	0	0	4	2	0	0	P2RX2	purinergic receptor P2X 2 [Source:HGNC Symbol;Acc:HGNC:15459]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04742//Taste transduction	K05216;K05216;K05216	GO:0005639//integral component of nuclear inner membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0045202//synapse;GO:0098794//postsynapse	GO:0000166//nucleotide binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005216//ion channel activity;GO:0005524//ATP binding;GO:0015267//channel activity;GO:0015276//ligand-gated ion channel activity;GO:0042802//identical protein binding	GO:0001666//response to hypoxia;GO:0002931//response to ischemia;GO:0003029//detection of hypoxic conditions in blood by carotid body chemoreceptor signaling;GO:0006811//ion transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0007528//neuromuscular junction development;GO:0007605//sensory perception of sound;GO:0009743//response to carbohydrate;GO:0010033//response to organic substance;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0014832//urinary bladder smooth muscle contraction;GO:0030432//peristalsis;GO:0033198//response to ATP;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0048266//behavioral response to pain;GO:0048741//skeletal muscle fiber development;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050909//sensory perception of taste;GO:0060079//excitatory postsynaptic potential;GO:0065008//regulation of biological quality;GO:0098655//cation transmembrane transport	--
ENSG00000187855	0	0	0	0	0	0	0	0	0	0	0	0	ASCL4	achaete-scute family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24311]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0043588//skin development	bHLH
ENSG00000187857	0	0	0	0	0	0	0	0	0	0	0	0	OR6C75	olfactory receptor family 6 subfamily C member 75 [Source:HGNC Symbol;Acc:HGNC:31304]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187860	2.879	3.045	2.378	2.106	1.655	1.473	103.45	125.85	79.68	79.34	82.64	63.66	CCDC157	coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187862	0	0	0	0	0	0	0	0	0	0	0	0	TTC24	tetratricopeptide repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:32348]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187866	5.468	5.876	5.98	5.17	5.227	6.563	624	674	504	437	504	545	PABIR1	PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 [Source:HGNC Symbol;Acc:HGNC:23490]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding	GO:0030307//positive regulation of cell growth;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043086//negative regulation of catalytic activity;GO:0044818//mitotic G2/M transition checkpoint	--
ENSG00000187867	0.043	0.021	0.058	0	0.024	0.088	2	1	2	0	1	3	PALM3	paralemmin 3 [Source:HGNC Symbol;Acc:HGNC:33274]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0008063//Toll signaling pathway;GO:0008360//regulation of cell shape;GO:0032496//response to lipopolysaccharide	--
ENSG00000187871	0	0	0	0	0	0	0	0	0	0	0	0	GFRAL	GDNF family receptor alpha like [Source:HGNC Symbol;Acc:HGNC:32789]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0005515//protein binding;GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0038023//signaling receptor activity	GO:0002023//reduction of food intake in response to dietary excess;GO:0007399//nervous system development;GO:0031098//stress-activated protein kinase signaling cascade;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000187889	8.346	7.836	6.993	4.417	5.074	7.369	551	520	341	216	283	354	FYB2	FYN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:27295]	-	-	-	-	GO:0001772//immunological synapse;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045121//membrane raft	GO:0005515//protein binding	GO:0007229//integrin-mediated signaling pathway;GO:0033627//cell adhesion mediated by integrin;GO:0050852//T cell receptor signaling pathway;GO:0072659//protein localization to plasma membrane	--
ENSG00000187902	0	0	0	0	0.009	0.031	0	0	0	0	1	3	SHISA7	shisa family member 7 [Source:HGNC Symbol;Acc:HGNC:35409]	-	-	-	-	"GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0032591//dendritic spine membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098839//postsynaptic density membrane;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0035255//ionotropic glutamate receptor binding;GO:0050811//GABA receptor binding	GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007613//memory;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0106040//regulation of GABA-A receptor activity;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1904717//regulation of AMPA glutamate receptor clustering;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000187905	0	0	0	0	0	0	0	0	0	0	0	0	LRRC74B	leucine rich repeat containing 74B [Source:HGNC Symbol;Acc:HGNC:34301]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000187908	0	0.032	0	0.051	0.023	0.053	0	5	0	3	2	4	DMBT1	deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:HGNC:2926]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13912	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031012//extracellular matrix;GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0035375//zymogen binding;GO:0038187//pattern recognition receptor activity;GO:0048306//calcium-dependent protein binding;GO:0050840//extracellular matrix binding	GO:0006897//endocytosis;GO:0006952//defense response;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0030855//epithelial cell differentiation;GO:0042494//detection of bacterial lipoprotein;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0051607//defense response to virus	--
ENSG00000187912	0.032	0.066	0	0	0	0	2	2	0	0	0	0	CLEC17A	C-type lectin domain containing 17A [Source:HGNC Symbol;Acc:HGNC:34520]	-	-	-	-	GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding;GO:0042806//fucose binding;GO:0046872//metal ion binding	-	--
ENSG00000187918	0	0	0	0	0	0	0	0	0	0	0	0	OR51I2	olfactory receptor family 51 subfamily I member 2 [Source:HGNC Symbol;Acc:HGNC:15201]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000187922	0.072	0.17	0	0	0.064	0.037	3	2	0	0	2	1	LCN10	lipocalin 10 [Source:HGNC Symbol;Acc:HGNC:20892]	-	-	-	-	GO:0005576//extracellular region	GO:0036094//small molecule binding	-	--
ENSG00000187942	0	0	0	0	0.056	0.08	0	0	0	0	2.25	4.84	LDLRAD2	low density lipoprotein receptor class A domain containing 2 [Source:HGNC Symbol;Acc:HGNC:32071]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000187944	0	0	0.049	0	0	0	0	0	1	0	0	0	C2orf66	chromosome 2 open reading frame 66 [Source:HGNC Symbol;Acc:HGNC:33809]	-	-	-	-	-	-	-	--
ENSG00000187950	0	0	0	0	0	0.019	0	0	0	0	0	1	OVCH1	ovochymase 1 [Source:HGNC Symbol;Acc:HGNC:23080]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000187954	17.921	18.475	21.241	20.764	19.341	18.059	592	662	549	534	604	451	CYHR1	cysteine and histidine rich 1 [Source:HGNC Symbol;Acc:HGNC:17806]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000187955	5.352	5.136	3.851	3.391	4.097	3.298	718	677	379	344	450	315	COL14A1	collagen type XIV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2191]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K08133	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005596//collagen type XIV trimer;GO:0005614//interstitial matrix;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0003723//RNA binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity	GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0098609//cell-cell adhesion	--
ENSG00000187957	0.34	0.457	0.04	3.317	2.558	1.994	23	31	2	166	146	98	DNER	delta/notch like EGF repeat containing [Source:HGNC Symbol;Acc:HGNC:24456]	-	-	-	-	GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body	GO:0004888//transmembrane signaling receptor activity;GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030276//clathrin binding	GO:0001764//neuron migration;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0007416//synapse assembly;GO:0007417//central nervous system development;GO:0010001//glial cell differentiation;GO:0048741//skeletal muscle fiber development	--
ENSG00000187959	0	0	0	0	0	0	0	0	0	0	0	0	CPSF4L	cleavage and polyadenylation specific factor 4 like [Source:HGNC Symbol;Acc:HGNC:33632]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05164//Influenza A;ko03015//mRNA surveillance pathway	K14404;K14404	GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0003723//RNA binding;GO:0046872//metal ion binding	GO:0098789//pre-mRNA cleavage required for polyadenylation	--
ENSG00000187961	2.153	2.57	2.125	2.494	1.966	2.203	89	110	67	74	79	78	KLHL17	kelch like family member 17 [Source:HGNC Symbol;Acc:HGNC:24023]	-	-	-	-	GO:0005615//extracellular space;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0032839//dendrite cytoplasm;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031208//POZ domain binding;GO:0051015//actin filament binding;GO:0060090//molecular adaptor activity	GO:0007420//brain development;GO:0016567//protein ubiquitination;GO:0030036//actin cytoskeleton organization	--
ENSG00000187969	0	0	0	0	0	0	0	0	0	0	0	0	ZCCHC13	zinc finger CCHC-type containing 13 [Source:HGNC Symbol;Acc:HGNC:31749]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0045182//translation regulator activity;GO:0046872//metal ion binding	GO:2000767//positive regulation of cytoplasmic translation	--
ENSG00000187980	0	0	0	0	0	0	0	0	0	0	0	0	PLA2G2C	phospholipase A2 group IIC [Source:HGNC Symbol;Acc:HGNC:9032]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0050482//arachidonic acid secretion	--
ENSG00000187987	1.276	0.465	0.661	0.454	0.488	0.358	49	23	23	13	24	17	ZSCAN23	zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000187994	1.367	1.6	1.611	4.069	3.368	1.6	65	53	45	61	60	57	RINL	Ras and Rab interactor like [Source:HGNC Symbol;Acc:HGNC:24795]	-	-	-	-	GO:0001726//ruffle;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030139//endocytic vesicle;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0031267//small GTPase binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000187997	0	0	0	0	0	0	0	0	0	0	0	0	C17orf99	chromosome 17 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:34490]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005125//cytokine activity	GO:0002250//adaptive immune response;GO:0002313//mature B cell differentiation involved in immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response;GO:2000558//positive regulation of immunoglobulin production in mucosal tissue	--
ENSG00000188000	0	0	0	0	0.018	0	0	0	0	0	1	0	OR7D2	olfactory receptor family 7 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8378]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell"	--
ENSG00000188001	0.035	0.117	0	0	0.157	0.029	4	1	0	0	9	1	TPRG1	tumor protein p63 regulated 1 [Source:HGNC Symbol;Acc:HGNC:24759]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000188010	22.619	23.623	21.051	20.319	16.088	19.171	341	358.21	235	227	205	210	MORN2	MORN repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:30166]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000188011	0	0	0	0	0	0	0	0	0	0	0	0	RTP5	receptor transporter protein 5 (putative) [Source:HGNC Symbol;Acc:HGNC:26585]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031849//olfactory receptor binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006612//protein targeting to membrane;GO:0051205//protein insertion into membrane	--
ENSG00000188015	0.414	0.442	0.44	0.175	0.461	0.747	6	6	5	2	6	7	S100A3	S100 calcium binding protein A3 [Source:HGNC Symbol;Acc:HGNC:10493]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000188021	15.673	15.807	16.081	16.018	17.676	15.62	1379	1398	1045	1044	1314	1000	UBQLN2	ubiquilin 2 [Source:HGNC Symbol;Acc:HGNC:12509]	Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Folding, sorting and degradation"	ko05014//Amyotrophic lateral sclerosis;ko04141//Protein processing in endoplasmic reticulum	K04523;K04523	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding	GO:0000045//autophagosome assembly;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0016241//regulation of macroautophagy;GO:0030433//ubiquitin-dependent ERAD pathway;GO:1900186//negative regulation of clathrin-dependent endocytosis;GO:1903071//positive regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1904021//negative regulation of G protein-coupled receptor internalization;GO:2000785//regulation of autophagosome assembly	--
ENSG00000188026	6.519	7.264	6.114	6.594	6.405	6.276	385	447	268	287	327	271	RILPL1	Rab interacting lysosomal protein like 1 [Source:HGNC Symbol;Acc:HGNC:26814]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0046983//protein dimerization activity	GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0060271//cilium assembly;GO:1901214//regulation of neuron death;GO:1903445//protein transport from ciliary membrane to plasma membrane	--
ENSG00000188032	0	0	0	0	0.079	0	0	0	0	0	2	0	C19orf67	chromosome 19 open reading frame 67 [Source:HGNC Symbol;Acc:HGNC:34354]	-	-	-	-	-	-	-	--
ENSG00000188033	1.173	0.903	0.705	0.554	0.822	1.173	115	115	66	52	88	91	ZNF490	zinc finger protein 490 [Source:HGNC Symbol;Acc:HGNC:23705]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188037	0	0	0	0	0	0	0	0	0	0	0	0	CLCN1	chloride voltage-gated channel 1 [Source:HGNC Symbol;Acc:HGNC:2019]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0042383//sarcolemma	GO:0005244//voltage-gated ion channel activity;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006936//muscle contraction;GO:0019227//neuronal action potential propagation;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport	--
ENSG00000188038	0	0.153	0.104	0	0	0.106	0	2	1	0	0	1	NRN1L	neuritin 1 like [Source:HGNC Symbol;Acc:HGNC:29811]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0046658//anchored component of plasma membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007399//nervous system development;GO:1990138//neuron projection extension	--
ENSG00000188039	9.495	8.328	6.63	6.067	8.869	7.745	990	1076	744	618	900	585	NWD1	NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0010628//positive regulation of gene expression;GO:0032088//negative regulation of NF-kappaB transcription factor activity	--
ENSG00000188042	13.943	14.929	12.237	13.646	13.832	13.511	1158	1240	750	841	972	817	ARL4C	ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030175//filopodium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0043014//alpha-tubulin binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0032456//endocytic recycling	--
ENSG00000188050	0	0	0	0	0	0.048	0	0	0	0	0	1	RNF133	ring finger protein 133 [Source:HGNC Symbol;Acc:HGNC:21154]	-	-	-	-	GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination	--
ENSG00000188051	0.712	0.638	0.9	1.058	1.236	1.174	30	27	28	33	44	36	TMEM221	transmembrane protein 221 [Source:HGNC Symbol;Acc:HGNC:21943]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000188056	0	0	0	0	0	0	0	0	0	0	0	0	TREML4	triggering receptor expressed on myeloid cells like 4 [Source:HGNC Symbol;Acc:HGNC:30807]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface	GO:0038023//signaling receptor activity	GO:0002376//immune system process;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0045087//innate immune response	--
ENSG00000188060	1.043	1.407	1.02	0.955	0.893	1.302	44	61	33	32	35	41	RAB42	"RAB42, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:28702]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019003//GDP binding	GO:0007265//Ras protein signal transduction	--
ENSG00000188064	0	0.033	0	0.03	0.054	0.12	0	2	0	1	3	4	WNT7B	Wnt family member 7B [Source:HGNC Symbol;Acc:HGNC:12787]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572;K00572	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0001701//in utero embryonic development;GO:0003338//metanephros morphogenesis;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0016332//establishment or maintenance of polarity of embryonic epithelium;GO:0021871//forebrain regionalization;GO:0022009//central nervous system vasculogenesis;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030324//lung development;GO:0031175//neuron projection development;GO:0032364//oxygen homeostasis;GO:0032536//regulation of cell projection size;GO:0042592//homeostatic process;GO:0045165//cell fate commitment;GO:0045669//positive regulation of osteoblast differentiation;GO:0046330//positive regulation of JNK cascade;GO:0048144//fibroblast proliferation;GO:0048568//embryonic organ development;GO:0048812//neuron projection morphogenesis;GO:0050808//synapse organization;GO:0051384//response to glucocorticoid;GO:0060070//canonical Wnt signaling pathway;GO:0060425//lung morphogenesis;GO:0060428//lung epithelium development;GO:0060429//epithelium development;GO:0060482//lobar bronchus development;GO:0060535//trachea cartilage morphogenesis;GO:0060560//developmental growth involved in morphogenesis;GO:0060669//embryonic placenta morphogenesis;GO:0060710//chorio-allantoic fusion;GO:0061180//mammary gland epithelium development;GO:0070307//lens fiber cell development;GO:0071300//cellular response to retinoic acid;GO:0072053//renal inner medulla development;GO:0072054//renal outer medulla development;GO:0072060//outer medullary collecting duct development;GO:0072061//inner medullary collecting duct development;GO:0072089//stem cell proliferation;GO:0072205//metanephric collecting duct development;GO:0072207//metanephric epithelium development;GO:0072236//metanephric loop of Henle development	--
ENSG00000188070	11.734	10.949	9.836	8.979	9.787	9.235	1088	1032	736	628	807	692	ZFTA	zinc finger translocation associated [Source:HGNC Symbol;Acc:HGNC:28449]	-	-	-	-	-	-	"GO:0045892//negative regulation of transcription, DNA-templated"	zf-BED
ENSG00000188076	0	0	0	0	0	0	0	0	0	0	0	0	SCGB1C1	secretoglobin family 1C member 1 [Source:HGNC Symbol;Acc:HGNC:18394]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000188086	0.052	0	0	0	0	0	1	0	0	0	0	0	PRSS45P	"serine protease 45, pseudogene [Source:HGNC Symbol;Acc:HGNC:30717]"	-	-	-	-	GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000188089	0	0	0	0	0	0.015	0	0	0	0	0	1	PLA2G4E	phospholipase A2 group IVE [Source:HGNC Symbol;Acc:HGNC:24791]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane	"GO:0004620//phospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008970//phospholipase A1 activity;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding"	GO:0006629//lipid metabolic process;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046475//glycerophospholipid catabolic process;GO:0070292//N-acylphosphatidylethanolamine metabolic process;GO:2001137//positive regulation of endocytic recycling	--
ENSG00000188092	4.631	3.444	3.528	5.111	3.949	5.398	201.44	148.75	112.81	163.63	137.98	155.85	GPR89B	G protein-coupled receptor 89B [Source:HGNC Symbol;Acc:HGNC:13840]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding;GO:0008308//voltage-gated anion channel activity	GO:0006811//ion transport;GO:0015031//protein transport;GO:0015698//inorganic anion transport;GO:0030217//T cell differentiation;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0051452//intracellular pH reduction	--
ENSG00000188095	0.112	0	0	0	0.174	0	2	0	0	0	5	0	MESP2	mesoderm posterior bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:29659]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001707//mesoderm formation;GO:0003007//heart morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0032525//somite rostral/caudal axis specification"	bHLH
ENSG00000188100	0	0	0	0	0	0	0	0	0	0	0	0	FAM25A	family with sequence similarity 25 member A [Source:HGNC Symbol;Acc:HGNC:23436]	-	-	-	-	-	-	-	--
ENSG00000188107	0	0	0	0	0	0	0	0	0	0	0	0	EYS	eyes shut homolog [Source:HGNC Symbol;Acc:HGNC:21555]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0033165//interphotoreceptor matrix;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005509//calcium ion binding	GO:0007601//visual perception;GO:0043403//skeletal muscle tissue regeneration;GO:0050896//response to stimulus;GO:0050908//detection of light stimulus involved in visual perception	--
ENSG00000188112	1.975	1.507	1.456	1.997	2.42	1.804	159	171	99	156	216	163	C6orf132	chromosome 6 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:21288]	-	-	-	-	-	-	-	--
ENSG00000188120	0	0	0	0	0	0	0	0	0	0	0	0	DAZ1	deleted in azoospermia 1 [Source:HGNC Symbol;Acc:HGNC:2682]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000188124	0	0	0.046	0.031	0	0.016	0	0	3	2	0	1	OR2AG2	olfactory receptor family 2 subfamily AG member 2 [Source:HGNC Symbol;Acc:HGNC:15143]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188130	5.45	4.937	5.176	6.516	5.424	6.335	201	183	141	178	169	170	MAPK12	mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:HGNC:6874]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Environmental adaptation;Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Endocrine and metabolic disease;Infectious disease: viral;Cell growth and death;Nervous system;Circulatory system;Infectious disease: parasitic;Cellular community - eukaryotes;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Immune system;Signal transduction;Nervous system;Endocrine system;Development and regeneration;Immune system;Nervous system;Signal transduction;Endocrine system;Immune system;Endocrine system;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Endocrine and metabolic disease;Drug resistance: antineoplastic;Sensory system;Immune system;Cancer: overview;Immune system;Endocrine system;Infectious disease: bacterial;Endocrine system;Immune system;Infectious disease: bacterial;Signal transduction	"ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05161//Hepatitis B;ko04218//Cellular senescence;ko04723//Retrograde endocannabinoid signaling;ko04261//Adrenergic signaling in cardiomyocytes;ko05140//Leishmaniasis;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04936//Alcoholic liver disease;ko04114//Oocyte meiosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04670//Leukocyte transendothelial migration;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko04917//Prolactin signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway"	K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441;K04441	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0006975//DNA damage induced protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0007517//muscle organ development;GO:0010952//positive regulation of peptidase activity;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0045445//myoblast differentiation;GO:0045786//negative regulation of cell cycle;GO:0051149//positive regulation of muscle cell differentiation;GO:0051726//regulation of cell cycle	--
ENSG00000188133	0.009	0.009	0	0	0.011	0.012	1	1	0	0	1	1	TMEM215	transmembrane protein 215 [Source:HGNC Symbol;Acc:HGNC:33816]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000188152	0.09	0.054	0	0.091	0.24	0.079	5	3	0	4	12	3.39	NUTM2G	NUT family member 2G [Source:HGNC Symbol;Acc:HGNC:23449]	-	-	-	-	-	-	-	--
ENSG00000188153	19.127	19.396	22.458	23.04	26.781	24.917	2275	2274	1544	1511	2005	1650	COL4A5	collagen type IV alpha 5 chain [Source:HGNC Symbol;Acc:HGNC:2207]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031594//neuromuscular junction;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007528//neuromuscular junction development;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway	--
ENSG00000188155	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-6	keratin associated protein 10-6 [Source:HGNC Symbol;Acc:HGNC:20523]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000188157	94.462	99.808	109.873	131.036	134.431	125.736	14356	15246	12333	14752	17261	13904	AGRN	agrin [Source:HGNC Symbol;Acc:HGNC:329]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06254	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043202//lysosomal lumen;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0071944//cell periphery	GO:0002162//dystroglycan binding;GO:0005200//structural constituent of cytoskeleton;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0033691//sialic acid binding;GO:0035374//chondroitin sulfate binding;GO:0043236//laminin binding;GO:0043395//heparan sulfate proteoglycan binding	GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007213//G protein-coupled acetylcholine receptor signaling pathway;GO:0007528//neuromuscular junction development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0030154//cell differentiation;GO:0043113//receptor clustering;GO:0043547//positive regulation of GTPase activity;GO:0045162//clustering of voltage-gated sodium channels;GO:0045887//positive regulation of synaptic assembly at neuromuscular junction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050808//synapse organization;GO:0051491//positive regulation of filopodium assembly	--
ENSG00000188158	0.74	0.461	0.556	0.475	0.598	0.347	126	79	70	60	86	43	NHS	NHS actin remodeling regulator [Source:HGNC Symbol;Acc:HGNC:7820]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016604//nuclear body;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection	-	GO:0002088//lens development in camera-type eye;GO:0030154//cell differentiation	--
ENSG00000188162	0	0	0	0.007	0	0	0	0	0	1	0	0	OTOG	otogelin [Source:HGNC Symbol;Acc:HGNC:8516]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031012//extracellular matrix	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0046556//alpha-L-arabinofuranosidase activity	GO:0007605//sensory perception of sound;GO:0008344//adult locomotory behavior;GO:0046373//L-arabinose metabolic process	--
ENSG00000188163	0.137	0.044	0	0	0.052	0	2	1	0	0	1	0	FAM166A	family with sequence similarity 166 member A [Source:HGNC Symbol;Acc:HGNC:33818]	-	-	-	-	GO:0005634//nucleus;GO:0036064//ciliary basal body	GO:0005515//protein binding	-	--
ENSG00000188167	0.811	0.846	0.965	0.781	1.138	1.166	70	70	62	46	72	69	TMPPE	transmembrane protein with metallophosphoesterase domain [Source:HGNC Symbol;Acc:HGNC:33865]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000188171	2.1	1.99	2.016	2.159	1.434	2.933	161	132.06	104	101	84	114	ZNF626	zinc finger protein 626 [Source:HGNC Symbol;Acc:HGNC:30461]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188175	0	0	0	0	0	0	0	0	0	0	0	0	HEPACAM2	HEPACAM family member 2 [Source:HGNC Symbol;Acc:HGNC:27364]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody;GO:0043231//intracellular membrane-bounded organelle;GO:0072686//mitotic spindle	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051301//cell division	--
ENSG00000188176	1.025	1.087	1.359	2.142	2.114	2.352	45	52	45	70	82	74	SMTNL2	smoothelin like 2 [Source:HGNC Symbol;Acc:HGNC:24764]	-	-	-	-	GO:0005815//microtubule organizing center;GO:0031430//M band;GO:0031674//I band;GO:0031941//filamentous actin	GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0008157//protein phosphatase 1 binding	GO:0030036//actin cytoskeleton organization;GO:0045907//positive regulation of vasoconstriction	--
ENSG00000188177	0.831	0.586	0.634	0.44	0.747	0.586	199	141	112	78	151	102	ZC3H6	zinc finger CCCH-type containing 6 [Source:HGNC Symbol;Acc:HGNC:24762]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0046872//metal ion binding	"GO:0008150//biological_process;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000188186	35.715	43.257	45.554	51.113	40.503	41.566	442	537	416	466.4	421	374	LAMTOR4	"late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 [Source:HGNC Symbol;Acc:HGNC:33772]"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20399	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071986//Ragulator complex	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0008361//regulation of cell size;GO:0032008//positive regulation of TOR signaling;GO:0038202//TORC1 signaling;GO:0050790//regulation of catalytic activity;GO:0061462//protein localization to lysosome;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000188191	13.948	13.164	14.049	13.789	12.949	9.819	582	594	442	446	520	333	PRKAR1B	protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]	Organismal Systems	Endocrine system	ko04910//Insulin signaling pathway	K04739	GO:0005737//cytoplasm;GO:0005771//multivesicular body;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005952//cAMP-dependent protein kinase complex;GO:0016020//membrane;GO:0045202//synapse;GO:0097546//ciliary base;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0030552//cAMP binding;GO:0034236//protein kinase A catalytic subunit binding	GO:0001932//regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007611//learning or memory;GO:0045859//regulation of protein kinase activity;GO:0050804//modulation of chemical synaptic transmission;GO:0098693//regulation of synaptic vesicle cycle;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1903367//positive regulation of fear response;GO:1904058//positive regulation of sensory perception of pain;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000480//negative regulation of cAMP-dependent protein kinase activity	--
ENSG00000188199	0.214	0.244	0.283	0.146	0.285	0.421	14.97	17.71	14.24	7.38	16.99	20.92	NUTM2B	NUT family member 2B [Source:HGNC Symbol;Acc:HGNC:23445]	-	-	-	-	-	-	-	--
ENSG00000188211	1.417	1.378	1.233	1.411	1.977	2.21	187	158	120	138	199	167	NCR3LG1	natural killer cell cytotoxicity receptor 3 ligand 1 [Source:HGNC Symbol;Acc:HGNC:42400]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003823//antigen binding;GO:0005515//protein binding	GO:0050776//regulation of immune response	--
ENSG00000188215	1.795	2.118	1.489	2.041	1.128	1.441	177	230	140	135	112	121	DCUN1D3	defective in cullin neddylation 1 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28734]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding	GO:0010225//response to UV-C;GO:0010332//response to gamma radiation;GO:0010564//regulation of cell cycle process;GO:0030308//negative regulation of cell growth;GO:0043065//positive regulation of apoptotic process;GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:2000434//regulation of protein neddylation;GO:2000435//negative regulation of protein neddylation;GO:2000436//positive regulation of protein neddylation	--
ENSG00000188219	0.099	0.029	0.085	0.118	0.256	0.033	7.76	1.32	2.65	4.62	13.14	1	POTEE	POTE ankyrin domain family member E [Source:HGNC Symbol;Acc:HGNC:33895]	-	-	-	-	GO:0005615//extracellular space;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001895//retina homeostasis;GO:0021762//substantia nigra development	--
ENSG00000188223	0	0	0.104	0.305	0.129	0.709	0	0	1.66	4.86	2.35	11.1	PSENEN	novel protein	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05010//Alzheimer disease;ko04330//Notch signaling pathway	K06170;K06170	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	-	GO:0007219//Notch signaling pathway	--
ENSG00000188227	0.821	0.517	0.389	0.427	0.632	0.781	72	50	27	33	49	38	ZNF793	zinc finger protein 793 [Source:HGNC Symbol;Acc:HGNC:33115]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188229	193.355	203.365	230.063	251.218	229.963	228.747	6268.53	6626.94	5508.65	6032.83	6298.67	5395.85	TUBB4B	tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0035578//azurophil granule lumen;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:1903561//extracellular vesicle	GO:0000166//nucleotide binding;GO:0003725//double-stranded RNA binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042288//MHC class I protein binding;GO:0051082//unfolded protein binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000188234	1.23	0.947	1.04	0.916	1.211	0.946	64.68	50.05	40.37	35.68	53.8	35.8	AGAP4	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 [Source:HGNC Symbol;Acc:HGNC:23459]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000188243	36.646	36.38	36.751	34.269	38.082	34.96	767	771	576	698	644	575	COMMD6	COMM domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24015]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0051059//NF-kappaB binding	GO:0032088//negative regulation of NF-kappaB transcription factor activity	--
ENSG00000188257	0.756	0.059	0.879	4.394	4.028	5.323	11	1	12	47	50	56	PLA2G2A	phospholipase A2 group IIA [Source:HGNC Symbol;Acc:HGNC:9031]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030141//secretory granule;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016042//lipid catabolic process;GO:0019835//cytolysis;GO:0034374//low-density lipoprotein particle remodeling;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036335//intestinal stem cell homeostasis;GO:0042742//defense response to bacterium;GO:0046337//phosphatidylethanolamine metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0050482//arachidonic acid secretion;GO:0050729//positive regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1902563//regulation of neutrophil activation	--
ENSG00000188263	0.076	0.06	0.07	0.072	0	0.052	10	8	7	7	0	5	IL17REL	interleukin 17 receptor E like [Source:HGNC Symbol;Acc:HGNC:33808]	-	-	-	-	-	GO:0030368//interleukin-17 receptor activity	GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000188266	0.921	1.3	1.122	2	1.358	0.897	49	36	30	36	28	30	HYKK	hydroxylysine kinase [Source:HGNC Symbol;Acc:HGNC:34403]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K18201;K18201	GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019202//amino acid kinase activity;GO:0047992//hydroxylysine kinase activity	GO:0006554//lysine catabolic process;GO:0016310//phosphorylation	--
ENSG00000188269	0	0	0	0	0	0	0	0	0	0	0	0	OR7A5	olfactory receptor family 7 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:8368]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188277	0.664	0.485	0.608	0.474	0.37	0.966	34	25	23	18	16	36	C15orf62	chromosome 15 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:34489]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005886//plasma membrane	-	GO:0007266//Rho protein signal transduction;GO:0008360//regulation of cell shape;GO:0030838//positive regulation of actin filament polymerization;GO:0031274//positive regulation of pseudopodium assembly	--
ENSG00000188282	0	0	0	0	0	0	0	0	0	0	0	0	RUFY4	RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804]	-	-	-	-	GO:0005776//autophagosome;GO:0031410//cytoplasmic vesicle	GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0046872//metal ion binding	GO:0000045//autophagosome assembly;GO:0006914//autophagy;GO:0016239//positive regulation of macroautophagy;GO:0071353//cellular response to interleukin-4	--
ENSG00000188283	2.744	1.742	2.802	2.449	2.31	2.478	160	144	142	110	137	107	ZNF383	zinc finger protein 383 [Source:HGNC Symbol;Acc:HGNC:18609]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031965//nuclear membrane	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188290	2.672	3.803	3.952	4.325	4.574	3.649	54	78	58	63	79	52	HES4	hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149]	Human Diseases	Infectious disease: viral	ko05165//Human papillomavirus infection	K09089	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009952//anterior/posterior pattern specification;GO:0030154//cell differentiation"	bHLH
ENSG00000188293	0	0	0	0	0	0	0	0	0	0	0	0	IGFL1	IGF like family member 1 [Source:HGNC Symbol;Acc:HGNC:24093]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005515//protein binding	-	--
ENSG00000188295	4.82	3.846	4.897	3.993	3.571	4.005	160	128.14	120	105	109	104	ZNF669	zinc finger protein 669 [Source:HGNC Symbol;Acc:HGNC:25736]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188305	0	0	0	0	0	0	0	0	0	0	0	0	PEAK3	PEAK family member 3 [Source:HGNC Symbol;Acc:HGNC:24793]	-	-	-	-	GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0043621//protein self-association	GO:0006468//protein phosphorylation;GO:0008360//regulation of cell shape;GO:0032956//regulation of actin cytoskeleton organization	--
ENSG00000188306	0.071	0.047	0.095	0	0.028	0.033	3	2	4	0	1	1	LRRIQ4	leucine rich repeats and IQ motif containing 4 [Source:HGNC Symbol;Acc:HGNC:34298]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000188312	1.368	0.598	0.906	0.817	1.066	0.597	99.8	103.39	92.62	78.52	69.36	74.73	CENPP	centromere protein P [Source:HGNC Symbol;Acc:HGNC:32933]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol"	GO:0005515//protein binding	GO:0034080//CENP-A containing nucleosome assembly	--
ENSG00000188313	12.374	11.153	11.663	9.9	9.841	13.451	391	383	260	226	266	283	PLSCR1	phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	"GO:0000287//magnesium ion binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0001618//virus receptor activity;GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0005154//epidermal growth factor receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0017124//SH3 domain binding;GO:0017128//phospholipid scramblase activity;GO:0019899//enzyme binding;GO:0032791//lead ion binding;GO:0042609//CD4 receptor binding;GO:0045340//mercury ion binding"	GO:0006659//phosphatidylserine biosynthetic process;GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0006953//acute-phase response;GO:0010288//response to lead ion;GO:0010628//positive regulation of gene expression;GO:0017121//plasma membrane phospholipid scrambling;GO:0030168//platelet activation;GO:0033003//regulation of mast cell activation;GO:0035456//response to interferon-beta;GO:0045071//negative regulation of viral genome replication;GO:0045089//positive regulation of innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046718//viral entry into host cell;GO:0050765//negative regulation of phagocytosis;GO:0051607//defense response to virus;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:1905820//positive regulation of chromosome separation;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Others
ENSG00000188315	1.003	2.883	1.74	2.334	2.366	1.409	78	101	58	65	102	66	C3orf62	chromosome 3 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:24771]	-	-	-	-	-	GO:0005515//protein binding	GO:0007283//spermatogenesis	--
ENSG00000188316	0.926	0.768	0.58	0.851	0.317	0.834	55.3	46.09	25.58	34.87	16	30.08	ENO4	enolase 4 [Source:HGNC Symbol;Acc:HGNC:31670]	Metabolism;Environmental Information Processing;Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Signal transduction;Global and overview maps;Folding, sorting and degradation;Global and overview maps;Carbohydrate metabolism"	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko03018//RNA degradation;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis	K01689;K01689;K01689;K01689;K01689;K01689	GO:0000015//phosphopyruvate hydratase complex;GO:0005575//cellular_component;GO:0097228//sperm principal piece	GO:0000287//magnesium ion binding;GO:0003674//molecular_function;GO:0004634//phosphopyruvate hydratase activity;GO:0016829//lyase activity	GO:0006096//glycolytic process;GO:0008150//biological_process;GO:0030317//flagellated sperm motility;GO:0044782//cilium organization	--
ENSG00000188321	3.42	4.161	3.111	2.24	3.432	2.733	120.63	131	106.95	67.44	85	81.34	ZNF559	zinc finger protein 559 [Source:HGNC Symbol;Acc:HGNC:28197]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188322	7.393	7.069	6.704	5.34	5.734	5.719	746	717	489	401	496	401	SBK1	SH3 domain binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:17699]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007420//brain development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation	--
ENSG00000188324	0	0	0	0	0	0	0	0	0	0	0	0	OR6C6	olfactory receptor family 6 subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:31293]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188334	0	0	0	0	0	0	0	0	0	0	0	0	BSPH1	binder of sperm protein homolog 1 [Source:HGNC Symbol;Acc:HGNC:33906]	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0008201//heparin binding	GO:0007338//single fertilization;GO:0048240//sperm capacitation	--
ENSG00000188338	77.413	79.647	76.34	64.733	67.542	66.831	4264	4359	3025	2685	3198	2586	SLC38A3	solute carrier family 38 member 3 [Source:HGNC Symbol;Acc:HGNC:18044]	Organismal Systems;Organismal Systems;Organismal Systems	Nervous system;Nervous system;Excretory system	ko04724//Glutamatergic synapse;ko04727//GABAergic synapse;ko04964//Proximal tubule bicarbonate reclamation	K13576;K13576;K13576	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane	GO:0005290//L-histidine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015182//L-asparagine transmembrane transporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity	GO:0003333//amino acid transmembrane transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0006867//asparagine transport;GO:0006868//glutamine transport;GO:0007420//brain development;GO:0007565//female pregnancy;GO:0015808//L-alanine transport;GO:0015817//histidine transport;GO:0051365//cellular response to potassium ion starvation;GO:0061402//positive regulation of transcription from RNA polymerase II promoter in response to acidic pH;GO:0089709//L-histidine transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:2000487//positive regulation of glutamine transport	--
ENSG00000188340	0	0	0	0	0	0	0	0	0	0	0	0	OR6N2	olfactory receptor family 6 subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:15035]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188342	24.452	23.401	19.982	16.155	15.009	18.32	1130	1087	682	553	586	616	GTF2F2	general transcription factor IIF subunit 2 [Source:HGNC Symbol;Acc:HGNC:4653]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03139	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005674//transcription factor TFIIF complex;GO:0015630//microtubule cytoskeleton;GO:0097550//transcription preinitiation complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032508//DNA duplex unwinding;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000188343	10.718	10.858	7.786	9.297	8.049	5.58	221.44	220.27	116.89	117.78	147.48	82.95	CIBAR1	CBY1 interacting BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30452]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0019898//extrinsic component of membrane;GO:0030061//mitochondrial crista;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0005543//phospholipid binding	GO:0007007//inner mitochondrial membrane organization;GO:0030030//cell projection organization;GO:0035108//limb morphogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0060271//cilium assembly;GO:0061024//membrane organization;GO:0097749//membrane tubulation	--
ENSG00000188352	23.724	28.663	30.213	34.916	33.945	40.007	2198	2267	1827	1834	1976	1955	FOCAD	focadhesin [Source:HGNC Symbol;Acc:HGNC:23377]	-	-	-	-	GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding	GO:0060147//regulation of posttranscriptional gene silencing	--
ENSG00000188368	1.12	1.507	0.976	0.884	0.901	1.568	34.23	47.65	23.06	21.16	24.21	37.32	PRR19	proline rich 19 [Source:HGNC Symbol;Acc:HGNC:33728]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding	-	--
ENSG00000188372	1.55	1.529	1.323	2.032	0.999	1.291	44.76	41.54	26.41	40.68	22.8	25.39	ZP3	zona pellucida glycoprotein 3 [Source:HGNC Symbol;Acc:HGNC:13189]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0035805//egg coat;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0032190//acrosin binding;GO:0035804//structural constituent of egg coat;GO:0042802//identical protein binding;GO:0048018//receptor ligand activity	"GO:0001809//positive regulation of type IV hypersensitivity;GO:0001825//blastocyst formation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002687//positive regulation of leukocyte migration;GO:0002922//positive regulation of humoral immune response;GO:0007165//signal transduction;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0032729//positive regulation of interferon-gamma production;GO:0032753//positive regulation of interleukin-4 production;GO:0035803//egg coat formation;GO:0042102//positive regulation of T cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048599//oocyte development;GO:0050729//positive regulation of inflammatory response;GO:2000344//positive regulation of acrosome reaction;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:2000368//positive regulation of acrosomal vesicle exocytosis;GO:2000386//positive regulation of ovarian follicle development;GO:2000388//positive regulation of antral ovarian follicle growth"	--
ENSG00000188373	0	0	0	0	0	0	0	0	0	0	0	0	C10orf99	chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0001664//G protein-coupled receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048018//receptor ligand activity	GO:0006935//chemotaxis;GO:0007186//G protein-coupled receptor signaling pathway;GO:0042742//defense response to bacterium;GO:0048247//lymphocyte chemotaxis;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051782//negative regulation of cell division;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:2000404//regulation of T cell migration	--
ENSG00000188375	0	0	0	0	0	0	0	0	0	0	0	0	H3-5	H3.5 histone [Source:HGNC Symbol;Acc:HGNC:33164]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity	GO:0030307//positive regulation of cell growth	--
ENSG00000188379	0	0	0	0	0	0	0	0	0	0	0	0	IFNA2	interferon alpha 2 [Source:HGNC Symbol;Acc:HGNC:5423]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	"GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006915//apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010629//negative regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0032696//negative regulation of interleukin-13 production;GO:0032714//negative regulation of interleukin-5 production;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043330//response to exogenous dsRNA;GO:0045581//negative regulation of T cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046597//negative regulation of viral entry into host cell;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus;GO:2000552//negative regulation of T-helper 2 cell cytokine production"	--
ENSG00000188385	0.175	0.092	0.129	0.056	0.187	0.146	22	13	13	5	22	16	JAKMIP3	Janus kinase and microtubule interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23523]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008017//microtubule binding;GO:0019900//kinase binding	-	--
ENSG00000188386	0	0	0	0	0	0	0	0	0	0	0	0	PPP3R2	"protein phosphatase 3 regulatory subunit B, beta [Source:HGNC Symbol;Acc:HGNC:9318]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cell growth and death;Development and regeneration;Nervous system;Immune system;Immune system;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Substance dependence;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04114//Oocyte meiosis;ko04380//Osteoclast differentiation;ko04724//Glutamatergic synapse;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04370//VEGF signaling pathway	K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268	GO:0005829//cytosol;GO:0005955//calcineurin complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0036126//sperm flagellum;GO:0097226//sperm mitochondrial sheath	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0046872//metal ion binding	GO:0007341//penetration of zona pellucida;GO:0050790//regulation of catalytic activity;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane	--
ENSG00000188389	0.115	0.137	0.062	0.217	0.163	0.316	4	6	2	7	6	10	PDCD1	programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760]	Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Immune system;Cancer: overview	ko04514//Cell adhesion molecules;ko04660//T cell receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06744;K06744;K06744	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002644//negative regulation of tolerance induction;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0007275//multicellular organism development;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0050776//regulation of immune response;GO:0050777//negative regulation of immune response;GO:0070234//positive regulation of T cell apoptotic process	--
ENSG00000188393	0	0	0	0	0	0	0	0	0	0	0	0	CLEC2A	C-type lectin domain family 2 member A [Source:HGNC Symbol;Acc:HGNC:24191]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042803//protein homodimerization activity	GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000188394	0	0	0.125	0.083	0.073	0.042	0	0	3	2	2	1	GPR21	G protein-coupled receptor 21 [Source:HGNC Symbol;Acc:HGNC:4476]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0042593//glucose homeostasis;GO:0046627//negative regulation of insulin receptor signaling pathway	--
ENSG00000188396	0.322	0.177	0.289	0	0	0.229	8	5	6	0	0	3	DYNLT4	dynein light chain Tctex-type 4 [Source:HGNC Symbol;Acc:HGNC:32315]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000188403	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1OR15-9	immunoglobulin heavy variable 1/OR15-9 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5569]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000188404	0	0.061	0	0.055	0.073	0	0	3	0	2	3	0	SELL	selectin L [Source:HGNC Symbol;Acc:HGNC:10720]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06495	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0002020//protease binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030246//carbohydrate binding;GO:0043208//glycosphingolipid binding;GO:0046872//metal ion binding;GO:0070492//oligosaccharide binding	GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling	--
ENSG00000188408	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB5	MAGE family member B5 [Source:HGNC Symbol;Acc:HGNC:23795]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000188419	7.25	5.149	5.703	4.566	5.437	6.033	786	562	455	367	489	474	CHM	CHM Rab escort protein [Source:HGNC Symbol;Acc:HGNC:1940]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005968//Rab-protein geranylgeranyltransferase complex	GO:0004663//Rab geranylgeranyltransferase activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0006612//protein targeting to membrane;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0007601//visual perception;GO:0016192//vesicle-mediated transport;GO:0018344//protein geranylgeranylation;GO:0050790//regulation of catalytic activity;GO:0050896//response to stimulus	--
ENSG00000188425	0	0	0	0	0	0	0	0	0	0	0	0	NANOS2	nanos C2HC-type zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:23292]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0030718//germ-line stem cell population maintenance;GO:0045835//negative regulation of meiotic nuclear division;GO:0048477//oogenesis;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	--
ENSG00000188428	6.449	5.97	6.394	7.66	4.328	5.384	347	314	186	176	195	213	BLOC1S5	biogenesis of lysosomal organelles complex 1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:18561]	-	-	-	-	GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex;GO:1904115//axon cytoplasm	GO:0005515//protein binding	GO:0008089//anterograde axonal transport;GO:0031175//neuron projection development;GO:0032402//melanosome transport;GO:0032438//melanosome organization;GO:0035646//endosome to melanosome transport;GO:0048490//anterograde synaptic vesicle transport;GO:0050942//positive regulation of pigment cell differentiation	--
ENSG00000188452	0.081	0.311	0.367	0.068	0.254	0.12	7.53	20.83	9.95	4.69	6.12	4.5	CERKL	ceramide kinase like [Source:HGNC Symbol;Acc:HGNC:21699]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm	GO:0001727//lipid kinase activity;GO:0003951//NAD+ kinase activity;GO:0016301//kinase activity;GO:0046625//sphingolipid binding	GO:0006665//sphingolipid metabolic process;GO:0016310//phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0046834//lipid phosphorylation	--
ENSG00000188467	24.931	22.869	22.064	27.712	23.098	24.405	973.09	896.23	638.32	801.07	766.18	694.18	SLC24A5	solute carrier family 24 member 5 [Source:HGNC Symbol;Acc:HGNC:20611]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0042470//melanosome	"GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0015297//antiporter activity;GO:0015368//calcium:cation antiporter activity"	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0030318//melanocyte differentiation;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0048022//negative regulation of melanin biosynthetic process;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport	--
ENSG00000188483	4.216	3.982	4.312	3.795	4.527	4.474	237	225	179	158	215	183	IER5L	immediate early response 5 like [Source:HGNC Symbol;Acc:HGNC:23679]	-	-	-	-	-	-	-	--
ENSG00000188486	15.563	16.013	16.885	21.252	16.559	18.596	501	517	399	514	453	433	H2AX	H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000794//condensed nuclear chromosome;GO:0001673//male germ cell nucleus;GO:0001741//XY body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005813//centrosome;GO:0016607//nuclear speck;GO:0035861//site of double-strand break;GO:0070062//extracellular exosome;GO:0090734//site of DNA damage"	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042393//histone binding;GO:0046982//protein heterodimerization activity	GO:0000077//DNA damage checkpoint signaling;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006334//nucleosome assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007283//spermatogenesis;GO:0010212//response to ionizing radiation;GO:0021987//cerebral cortex development;GO:0045739//positive regulation of DNA repair;GO:0051321//meiotic cell cycle;GO:0071480//cellular response to gamma radiation;GO:0090398//cellular senescence	--
ENSG00000188487	0.022	0	0	0	0.019	0.042	1	0	0	0	1	1	INSC	INSC spindle orientation adaptor protein [Source:HGNC Symbol;Acc:HGNC:33116]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0032991//protein-containing complex;GO:0045179//apical cortex	GO:0005515//protein binding;GO:0008093//cytoskeletal anchor activity;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity	GO:0000132//establishment of mitotic spindle orientation;GO:0007399//nervous system development;GO:0008356//asymmetric cell division;GO:0009786//regulation of asymmetric cell division;GO:0030154//cell differentiation;GO:0031647//regulation of protein stability;GO:0045176//apical protein localization	--
ENSG00000188488	3.774	3.724	3.781	1.905	2.553	4.055	152	167	109	65	77	137	SERPINA5	serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03913	GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0031091//platelet alpha granule;GO:0031094//platelet dense tubular network;GO:0032991//protein-containing complex;GO:0036024//protein C inhibitor-TMPRSS7 complex;GO:0036025//protein C inhibitor-TMPRSS11E complex;GO:0036026//protein C inhibitor-PLAT complex;GO:0036027//protein C inhibitor-PLAU complex;GO:0036028//protein C inhibitor-thrombin complex;GO:0036029//protein C inhibitor-KLK3 complex;GO:0036030//protein C inhibitor-plasma kallikrein complex;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0097181//protein C inhibitor-coagulation factor V complex;GO:0097182//protein C inhibitor-coagulation factor Xa complex;GO:0097183//protein C inhibitor-coagulation factor XI complex	GO:0001972//retinoic acid binding;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0030414//peptidase inhibitor activity;GO:0031210//phosphatidylcholine binding;GO:0032190//acrosin binding	GO:0006869//lipid transport;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0051346//negative regulation of hydrolase activity	--
ENSG00000188493	6.381	6.158	7.495	6.077	6.99	6.649	394	395	292	283	365	308	C19orf54	chromosome 19 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:24758]	-	-	-	-	-	-	-	--
ENSG00000188501	3.299	3.599	3.816	3.181	2.456	3.27	158.52	176.06	124.84	108.06	100.52	124	LCTL	lactase like [Source:HGNC Symbol;Acc:HGNC:15583]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds"	GO:0002089//lens morphogenesis in camera-type eye;GO:0005975//carbohydrate metabolic process;GO:0007601//visual perception;GO:0050896//response to stimulus	--
ENSG00000188505	25.9	28.73	20.294	16.016	16.007	16.708	1061	1183	614	486	554	498	NCCRP1	"NCCRP1, F-box associated domain containing [Source:HGNC Symbol;Acc:HGNC:33739]"	-	-	-	-	GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006516//glycoprotein catabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000188508	0.113	0	0	0	0	0.156	1	0	0	0	0	1	KRTDAP	keratinocyte differentiation associated protein [Source:HGNC Symbol;Acc:HGNC:16313]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0042599//lamellar body	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0008544//epidermis development;GO:0030154//cell differentiation	--
ENSG00000188517	0.064	0.243	0.115	0.017	0.038	0.009	9	21	7	2	4	1	COL25A1	collagen type XXV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:18603]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K24356	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0062023//collagen-containing extracellular matrix	GO:0001540//amyloid-beta binding;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	-	--
ENSG00000188522	4.161	4.451	4.284	4.035	4.302	4.133	451	485	343	324	393.99	326	FAM83G	family with sequence similarity 83 member G [Source:HGNC Symbol;Acc:HGNC:32554]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007165//signal transduction;GO:0030509//BMP signaling pathway	--
ENSG00000188523	0.279	0.443	0.303	0.113	0.162	0.115	10	14	8	3	4	3	CFAP77	cilia and flagella associated protein 77 [Source:HGNC Symbol;Acc:HGNC:33776]	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000188529	33.351	27.902	30.01	26.321	24.561	33.51	1615	1407	1095	965	1063	1150	SRSF10	serine and arginine rich splicing factor 10 [Source:HGNC Symbol;Acc:HGNC:16713]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12900	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0043679//axon terminus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0050733//RS domain binding;GO:0051082//unfolded protein binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006376//mRNA splice site selection;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0016482//cytosolic transport;GO:0043484//regulation of RNA splicing;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000188536	0.084	0	0	0	1.684	0	1	0	0	0	17	0	HBA2	hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824]	Human Diseases;Human Diseases	Infectious disease: parasitic;Infectious disease: parasitic	ko05143//African trypanosomiasis;ko05144//Malaria	K13822;K13822	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0031838//haptoglobin-hemoglobin complex;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0010942//positive regulation of cell death;GO:0015670//carbon dioxide transport;GO:0015671//oxygen transport;GO:0030185//nitric oxide transport;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000188542	2.528	2.018	2.491	1.679	2.573	1.436	80.35	67	57	42.83	70.31	49.51	DUSP28	dual specificity phosphatase 28 [Source:HGNC Symbol;Acc:HGNC:33237]	-	-	-	-	-	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000188549	8.039	8.77	7.785	8.673	8.195	9.128	830	735	632	654	761	730	CCDC9B	coiled-coil domain containing 9B [Source:HGNC Symbol;Acc:HGNC:33488]	-	-	-	-	-	GO:0003723//RNA binding	-	--
ENSG00000188554	37.495	36.138	33.116	27.805	31.171	33.351	3373	3211	2254	1808	2370	2100	NBR1	NBR1 autophagy cargo receptor [Source:HGNC Symbol;Acc:HGNC:6746]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K17987	GO:0000407//phagophore assembly site;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031410//cytoplasmic vesicle;GO:0031430//M band;GO:0043231//intracellular membrane-bounded organelle;GO:0043235//receptor complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding	GO:0016236//macroautophagy;GO:0030500//regulation of bone mineralization;GO:0032872//regulation of stress-activated MAPK cascade;GO:0045668//negative regulation of osteoblast differentiation	--
ENSG00000188558	0	0	0	0	0	0	0	0	0	0	0	0	OR2G6	olfactory receptor family 2 subfamily G member 6 [Source:HGNC Symbol;Acc:HGNC:27019]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188559	6.845	6.795	7.05	5.209	5.795	6.37	1315	1329	1019	758	943	888	RALGAPA2	Ral GTPase activating protein catalytic subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:16207]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005096//GTPase activator activity;GO:0046982//protein heterodimerization activity	GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000188566	5.018	5.001	5.862	5.243	6.207	5.121	434.16	464.33	377.32	340	412.81	332.14	NDOR1	NADPH dependent diflavin oxidoreductase 1 [Source:HGNC Symbol;Acc:HGNC:29838]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton;GO:0048471//perinuclear region of cytoplasm	"GO:0003958//NADPH-hemoprotein reductase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0010181//FMN binding;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0016731//oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0070402//NADPH binding;GO:0071949//FAD binding"	GO:0008219//cell death;GO:0016226//iron-sulfur cluster assembly;GO:0022900//electron transport chain;GO:0036245//cellular response to menadione	--
ENSG00000188573	1.232	1.406	1.08	1.321	1.588	1.146	34	39	22	27	37	23	FBLL1	fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14563	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0031428//box C/D RNP complex;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0008649//rRNA methyltransferase activity;GO:0016740//transferase activity;GO:1990259//histone-glutamine methyltransferase activity	GO:0000494//box C/D RNA 3'-end processing;GO:0001835//blastocyst hatching;GO:0006364//rRNA processing;GO:0031167//rRNA methylation;GO:0032259//methylation;GO:1990258//histone glutamine methylation	--
ENSG00000188580	0.243	0.314	0.471	0.457	0.776	0.502	17	20	22	22	25	24	NKAIN2	sodium/potassium transporting ATPase interacting 2 [Source:HGNC Symbol;Acc:HGNC:16443]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0002028//regulation of sodium ion transport	--
ENSG00000188581	0.053	0	0	0	0	0	1	0	0	0	0	0	KRTAP1-1	keratin associated protein 1-1 [Source:HGNC Symbol;Acc:HGNC:16772]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000188582	1.533	1.24	1.853	2.012	1.959	2.559	289	235	258	281	312	351	PAQR9	progestin and adipoQ receptor family member 9 [Source:HGNC Symbol;Acc:HGNC:30131]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005496//steroid binding;GO:0008289//lipid binding;GO:0038023//signaling receptor activity	-	--
ENSG00000188585	0	0	0	0	0	0	0	0	0	0	0	0	CLEC20A	C-type lectin domain containing 20A [Source:HGNC Symbol;Acc:HGNC:34521]	-	-	-	-	-	GO:0030246//carbohydrate binding	-	--
ENSG00000188596	0.22	0.59	0.243	0.121	0.108	0.297	36.08	41	23	9.87	13	12	CFAP54	cilia and flagella associated protein 54 [Source:HGNC Symbol;Acc:HGNC:26456]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	-	GO:0007283//spermatogenesis;GO:0030030//cell projection organization;GO:0030154//cell differentiation;GO:0060271//cilium assembly;GO:0060294//cilium movement involved in cell motility;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance	--
ENSG00000188603	37.165	34.674	42.387	50.045	41.052	46.528	1252.27	1204.81	1018.29	1199.86	1203.56	1128.97	CLN3	"CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074]"	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12389	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005773//vacuole;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043005//neuron projection;GO:0044754//autolysosome;GO:0045121//membrane raft;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0051861//glycolipid binding;GO:0120146//sulfatide binding	"GO:0001508//action potential;GO:0001934//positive regulation of protein phosphorylation;GO:0006865//amino acid transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0007040//lysosome organization;GO:0007042//lysosomal lumen acidification;GO:0007611//learning or memory;GO:0008306//associative learning;GO:0009992//cellular water homeostasis;GO:0010506//regulation of autophagy;GO:0010762//regulation of fibroblast migration;GO:0016236//macroautophagy;GO:0016243//regulation of autophagosome size;GO:0016477//cell migration;GO:0016485//protein processing;GO:0030036//actin cytoskeleton organization;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035752//lysosomal lumen pH elevation;GO:0036359//renal potassium excretion;GO:0042133//neurotransmitter metabolic process;GO:0042987//amyloid precursor protein catabolic process;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0044857//plasma membrane raft organization;GO:0045861//negative regulation of proteolysis;GO:0046474//glycerophospholipid biosynthetic process;GO:0046836//glycolipid transport;GO:0047496//vesicle transport along microtubule;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048549//positive regulation of pinocytosis;GO:0050885//neuromuscular process controlling balance;GO:0051453//regulation of intracellular pH;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051489//regulation of filopodium assembly;GO:0051493//regulation of cytoskeleton organization;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0061024//membrane organization;GO:0061909//autophagosome-lysosome fusion;GO:0070613//regulation of protein processing;GO:0072657//protein localization to membrane;GO:0072659//protein localization to plasma membrane;GO:0090160//Golgi to lysosome transport;GO:0090384//phagosome-lysosome docking;GO:0090385//phagosome-lysosome fusion;GO:0097352//autophagosome maturation;GO:0106049//regulation of cellular response to osmotic stress;GO:1900079//regulation of arginine biosynthetic process;GO:1901096//regulation of autophagosome maturation;GO:1903076//regulation of protein localization to plasma membrane;GO:1903826//arginine transmembrane transport;GO:1905146//lysosomal protein catabolic process;GO:1905162//regulation of phagosome maturation;GO:1905244//regulation of modification of synaptic structure;GO:2001288//positive regulation of caveolin-mediated endocytosis"	--
ENSG00000188610	0.113	0.108	0.039	0.321	0.302	0.156	4.17	4	1	9.6	11.04	4.15	FAM72B	family with sequence similarity 72 member B [Source:HGNC Symbol;Acc:HGNC:24805]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000188611	0.659	0.808	0.679	0.376	0.738	0.631	46.46	45.5	51.52	21.88	33.85	29.31	ASAH2	N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K12349;K12349;K12349	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0017040//N-acylsphingosine amidohydrolase activity;GO:0046872//metal ion binding;GO:0102121//ceramidase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006670//sphingosine metabolic process;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process;GO:0007346//regulation of mitotic cell cycle;GO:0042759//long-chain fatty acid biosynthetic process;GO:0044241//lipid digestion;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0046514//ceramide catabolic process;GO:0071345//cellular response to cytokine stimulus;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000188612	57.175	57.833	51.84	55.349	45.167	54.675	2677	2564	1960	1854	1812	2079	SUMO2	small ubiquitin like modifier 2 [Source:HGNC Symbol;Acc:HGNC:11125]	Human Diseases;Genetic Information Processing	Cardiovascular disease;Translation	ko05418//Fluid shear stress and atherosclerosis;ko03013//Nucleocytoplasmic transport	K12160;K12160	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding	GO:0016925//protein sumoylation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000188613	72.844	62.037	82.557	147.399	125.137	168.814	2952	2594	2570	4636	4345	5360	NANOS1	nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030371//translation repressor activity;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0001894//tissue homeostasis;GO:0006417//regulation of translation;GO:0010608//posttranscriptional regulation of gene expression;GO:0010631//epithelial cell migration;GO:0016477//cell migration;GO:0017148//negative regulation of translation;GO:0048477//oogenesis;GO:0098749//cerebellar neuron development;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	--
ENSG00000188620	0	0	0	0	0	0	0	0	0	0	0	0	HMX3	H6 family homeobox 3 [Source:HGNC Symbol;Acc:HGNC:5019]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007420//brain development;GO:0007566//embryo implantation;GO:0030154//cell differentiation;GO:0042472//inner ear morphogenesis;GO:0043583//ear development;GO:0050885//neuromuscular process controlling balance;GO:0060135//maternal process involved in female pregnancy"	Homeobox
ENSG00000188624	0	0	0	0	0	0	0	0	0	0	0	0	IGFL3	IGF like family member 3 [Source:HGNC Symbol;Acc:HGNC:32930]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding	GO:0008150//biological_process	--
ENSG00000188626	0.076	0.028	0.085	0.052	0.013	0.013	8.49	3.17	6.96	4.25	1.19	1.05	GOLGA8M	golgin A8 family member M [Source:HGNC Symbol;Acc:HGNC:44404]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000188629	1.954	1.922	1.142	1.856	1.417	1.19	71.05	72.22	33.1	49.16	47.17	33.89	ZNF177	zinc finger protein 177 [Source:HGNC Symbol;Acc:HGNC:12966]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0072562//blood microparticle	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188636	15.729	17.278	17.467	16.755	16.722	17.302	1768	1952	1450	1395	1588	1415	RTL6	retrotransposon Gag like 6 [Source:HGNC Symbol;Acc:HGNC:13343]	-	-	-	-	-	-	-	--
ENSG00000188641	6.911	6.116	6.341	5.09	4.582	5.959	581	535	403	327	327	383	DPYD	dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism;Metabolism of other amino acids;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism;ko00410//beta-Alanine metabolism;ko00770//Pantothenate and CoA biosynthesis	K00207;K00207;K00207;K00207;K00207	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0002058//uracil binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017113//dihydropyrimidine dehydrogenase (NADP+) activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006145//purine nucleobase catabolic process;GO:0006208//pyrimidine nucleobase catabolic process;GO:0006210//thymine catabolic process;GO:0006212//uracil catabolic process;GO:0006214//thymidine catabolic process;GO:0006248//CMP catabolic process;GO:0006249//dCMP catabolic process;GO:0019483//beta-alanine biosynthetic process;GO:0046050//UMP catabolic process;GO:0046079//dUMP catabolic process	--
ENSG00000188643	35.397	38.063	32.892	34.573	33.043	35.958	847	910	580	604	674	617	S100A16	S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0051592//response to calcium ion	--
ENSG00000188647	6.746	4.273	5.112	4.995	4.765	4.751	1311	836	696	613	737	685	PTAR1	protein prenyltransferase alpha subunit repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:30449]	-	-	-	-	GO:0005737//cytoplasm	GO:0004659//prenyltransferase activity;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity	GO:0018342//protein prenylation	--
ENSG00000188649	0	0	0	0	0.093	0	0	0	0	0	2	0	CC2D2B	coiled-coil and C2 domain containing 2B [Source:HGNC Symbol;Acc:HGNC:31666]	-	-	-	-	GO:0035869//ciliary transition zone	-	GO:1904491//protein localization to ciliary transition zone;GO:1905515//non-motile cilium assembly	--
ENSG00000188655	0	0	0	0	0	0	0	0	0	0	0	0	RNASE9	ribonuclease A family member 9 (inactive) [Source:HGNC Symbol;Acc:HGNC:20673]	-	-	-	-	GO:0005576//extracellular region	GO:0003676//nucleic acid binding	-	--
ENSG00000188659	3.592	1.647	1.193	0.677	1.428	2.441	91	73	49	33	49	66	SAXO2	stabilizer of axonemal microtubules 2 [Source:HGNC Symbol;Acc:HGNC:33727]	-	-	-	-	GO:0005634//nucleus;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005879//axonemal microtubule;GO:0036064//ciliary basal body;GO:0036126//sperm flagellum	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0034453//microtubule anchoring	--
ENSG00000188672	0.201	0.25	0.218	0.172	0.268	0	5	9	4	4	7	0	RHCE	Rh blood group CcEe antigens [Source:HGNC Symbol;Acc:HGNC:10008]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008519//ammonium transmembrane transporter activity	GO:0015696//ammonium transport;GO:0072488//ammonium transmembrane transport	--
ENSG00000188674	0	0	0	0	0	0.135	0	0	0	0	0	2	C2orf80	chromosome 2 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:34352]	-	-	-	-	-	-	-	--
ENSG00000188676	0	0	0	0	0	0	0	0	0	0	0	0	IDO2	"indoleamine 2,3-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:27269]"	Metabolism;Human Diseases;Metabolism	Global and overview maps;Infectious disease: parasitic;Amino acid metabolism	ko01100//Metabolic pathways;ko05143//African trypanosomiasis;ko00380//Tryptophan metabolism	K00463;K00463;K00463	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0002376//immune system process;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0034354//'de novo' NAD biosynthetic process from tryptophan	--
ENSG00000188677	6.072	7.14	5.277	7.679	7.447	5.403	262	362	198	230	284	197	PARVB	parvin beta [Source:HGNC Symbol;Acc:HGNC:14653]	Cellular Processes	Cellular community - eukaryotes	ko04510//Focal adhesion	K06275	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0030031//cell projection assembly;GO:0030032//lamellipodium assembly;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0071963//establishment or maintenance of cell polarity regulating cell shape	--
ENSG00000188687	76.241	80.458	82.423	98.46	101.299	85.451	5566.22	5901.03	4519.14	5613.5	6446.88	4342.97	SLC4A5	solute carrier family 4 member 5 [Source:HGNC Symbol;Acc:HGNC:18168]	Organismal Systems	Digestive system	ko04976//Bile secretion	K13857	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005452//inorganic anion exchanger activity;GO:0008509//anion transmembrane transporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0015301//anion:anion antiporter activity;GO:0022857//transmembrane transporter activity	GO:0002064//epithelial cell development;GO:0003014//renal system process;GO:0003073//regulation of systemic arterial blood pressure;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006820//anion transport;GO:0010468//regulation of gene expression;GO:0015698//inorganic anion transport;GO:0015701//bicarbonate transport;GO:0033326//cerebrospinal fluid secretion;GO:0035725//sodium ion transmembrane transport;GO:0048311//mitochondrion distribution;GO:0050801//ion homeostasis;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0060041//retina development in camera-type eye;GO:0098656//anion transmembrane transport	--
ENSG00000188690	27.553	34	33.312	32.074	32.324	31.81	798	979	710	691	787	664	UROS	uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01719;K01719	GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004852//uroporphyrinogen-III synthase activity;GO:0005542//folic acid binding;GO:0016829//lyase activity	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006780//uroporphyrinogen III biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0033014//tetrapyrrole biosynthetic process;GO:0046677//response to antibiotic;GO:0070541//response to platinum ion;GO:0071243//cellular response to arsenic-containing substance;GO:0071418//cellular response to amine stimulus	--
ENSG00000188691	0	0	0	0	0	0	0	0	0	0	0	0	OR56A5	olfactory receptor family 56 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:14792]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000188694	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP24-1	keratin associated protein 24-1 [Source:HGNC Symbol;Acc:HGNC:33902]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005198//structural molecule activity	-	--
ENSG00000188706	25.502	26.476	25.4	28.468	28.266	25.466	1727	1814	1289	1459	1621	1252	ZDHHC9	zinc finger DHHC-type palmitoyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:18475]	-	-	-	-	GO:0000139//Golgi membrane;GO:0002178//palmitoyltransferase complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031228//intrinsic component of Golgi membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0043849//Ras palmitoyltransferase activity	GO:0000165//MAPK cascade;GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation	--
ENSG00000188710	0.117	0.117	0.158	0.476	0.069	0.12	4	1	4	6	2	3	QRFP	pyroglutamylated RFamide peptide [Source:HGNC Symbol;Acc:HGNC:29982]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005184//neuropeptide hormone activity;GO:0031854//orexigenic neuropeptide QRFP receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0007625//grooming behavior;GO:0007626//locomotory behavior;GO:0045777//positive regulation of blood pressure;GO:0060259//regulation of feeding behavior	--
ENSG00000188716	0	0	0.058	0	0.05	0	0	0	1	0	1	0	DUSP29	dual specificity phosphatase 29 [Source:HGNC Symbol;Acc:HGNC:23481]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0042803//protein homodimerization activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042593//glucose homeostasis;GO:0042692//muscle cell differentiation;GO:0043409//negative regulation of MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade	--
ENSG00000188725	18.017	18.485	20.541	18.271	16.898	19.609	747	720	556	558	593	580	SMIM15	small integral membrane protein 15 [Source:HGNC Symbol;Acc:HGNC:33861]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000188729	0.185	0.163	0.167	0.083	0.106	0.211	12	11	8	4	6	10	OSTN	osteocrin [Source:HGNC Symbol;Acc:HGNC:29961]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0003416//endochondral bone growth;GO:0007166//cell surface receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0030154//cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0046325//negative regulation of glucose import;GO:1903860//negative regulation of dendrite extension	--
ENSG00000188730	0	0	0	0	0	0	0	0	0	0	0	0	VWC2	von Willebrand factor C domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30200]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005614//interstitial matrix;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0010811//positive regulation of cell-substrate adhesion;GO:0030514//negative regulation of BMP signaling pathway;GO:0045666//positive regulation of neuron differentiation	--
ENSG00000188732	4.566	2.361	2.738	4.065	4.044	5.57	87	51	40	58	66	78	FAM221A	family with sequence similarity 221 member A [Source:HGNC Symbol;Acc:HGNC:27977]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000188735	4.088	3.886	5.656	4.767	5.855	5.296	446.16	436.33	369.78	441.47	465.02	422.44	TMEM120B	transmembrane protein 120B [Source:HGNC Symbol;Acc:HGNC:32008]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0045444//fat cell differentiation;GO:0051291//protein heterooligomerization	--
ENSG00000188738	0.841	0.315	0.225	0.291	0.548	0.366	71.63	25.8	13.33	17.89	51.35	26.61	FSIP2	fibrous sheath interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:21675]	-	-	-	-	GO:0097224//sperm connecting piece;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0097229//sperm end piece	GO:0003674//molecular_function	GO:0007288//sperm axoneme assembly;GO:0030317//flagellated sperm motility;GO:0061512//protein localization to cilium	--
ENSG00000188739	11.068	12.188	9.15	9.531	8.572	7.474	376	421.09	227.2	209.23	249.16	186.17	RBM34	RNA binding motif protein 34 [Source:HGNC Symbol;Acc:HGNC:28965]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000188747	2.055	2.952	1.617	3.631	2.757	3.378	69	96	38	88	76	80	NOXA1	NADPH oxidase activator 1 [Source:HGNC Symbol;Acc:HGNC:10668]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043020//NADPH oxidase complex	GO:0005515//protein binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding	GO:0006801//superoxide metabolic process;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0042554//superoxide anion generation;GO:0050790//regulation of catalytic activity;GO:0060263//regulation of respiratory burst	--
ENSG00000188760	3	4.002	3.637	5.15	3.851	4.712	125	175	112	166	137	103	TMEM198	transmembrane protein 198 [Source:HGNC Symbol;Acc:HGNC:33704]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000188761	0.01	0.038	0	0	0	0	1	4	0	0	0	0	BCL2L15	BCL2 like 15 [Source:HGNC Symbol;Acc:HGNC:33624]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process	--
ENSG00000188763	1.235	1.085	1.504	1.611	1.559	1.216	60	53	54	58	64	43	FZD9	frizzled class receptor 9 [Source:HGNC Symbol;Acc:HGNC:4047]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04916//Melanogenesis;ko05217//Basal cell carcinoma	K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842;K02842	GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031527//filopodium membrane;GO:0031966//mitochondrial membrane;GO:0048471//perinuclear region of cytoplasm;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity;GO:0042813//Wnt-activated receptor activity;GO:0046982//protein heterodimerization activity	GO:0001503//ossification;GO:0001836//release of cytochrome c from mitochondria;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0007405//neuroblast proliferation;GO:0007611//learning or memory;GO:0016055//Wnt signaling pathway;GO:0030183//B cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0043065//positive regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051726//regulation of cell cycle;GO:0051902//negative regulation of mitochondrial depolarization;GO:0060070//canonical Wnt signaling pathway;GO:0060546//negative regulation of necroptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0099173//postsynapse organization;GO:0099566//regulation of postsynaptic cytosolic calcium ion concentration;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1904393//regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1904394//negative regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1990523//bone regeneration;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000188766	2.027	1.312	1.404	2.426	1.867	1.966	141	131	103	154	157	142	SPRED3	sprouty related EVH1 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:31041]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0019901//protein kinase binding	GO:0001933//negative regulation of protein phosphorylation;GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1902747//negative regulation of lens fiber cell differentiation	--
ENSG00000188770	5.312	8.344	9.787	5.481	5.445	3.253	158	240	215	116	127	67	OPTC	opticin [Source:HGNC Symbol;Acc:HGNC:8158]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0030199//collagen fibril organization	--
ENSG00000188771	0	0	0	0	0	0	0	0	0	0	0	0	PLET1	placenta expressed transcript 1 [Source:HGNC Symbol;Acc:HGNC:30053]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane	-	"GO:0001953//negative regulation of cell-matrix adhesion;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0035313//wound healing, spreading of epidermal cells"	--
ENSG00000188778	0	0	0	0	0	0	0	0	0	0	0	0	ADRB3	adrenoceptor beta 3 [Source:HGNC Symbol;Acc:HGNC:288]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Environmental adaptation;Cancer: overview;Signal transduction;Digestive system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko04970//Salivary secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K04143;K04143;K04143;K04143;K04143;K04143;K04143;K04143	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004939//beta-adrenergic receptor activity;GO:0005515//protein binding;GO:0015052//beta3-adrenergic receptor activity;GO:0042803//protein homodimerization activity;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding	"GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006112//energy reserve metabolic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0043410//positive regulation of MAPK cascade;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis"	--
ENSG00000188779	0.04	0	0	0.018	0.032	0.018	3	0	0	1	2	1	SKOR1	SKI family transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:21326]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0110165//cellular anatomical entity	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046332//SMAD binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030514//negative regulation of BMP signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000188782	0	0	0	0	0	0	0	0	0	0	0	0	CATSPER4	cation channel sperm associated 4 [Source:HGNC Symbol;Acc:HGNC:23220]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005216//ion channel activity;GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0048240//sperm capacitation;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000188783	19.873	20.328	25.697	22.914	24.324	23.844	2378	2445	2271	2031	2459	2076	PRELP	proline and arginine rich end leucine rich repeat protein [Source:HGNC Symbol;Acc:HGNC:9357]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030021//extracellular matrix structural constituent conferring compression resistance	GO:0001501//skeletal system development;GO:0007569//cell aging	--
ENSG00000188784	0	0	0	0	0	0	0	0	0	0	0	0	PLA2G2E	phospholipase A2 group IIE [Source:HGNC Symbol;Acc:HGNC:13414]	Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Signal transduction;Circulatory system;Digestive system;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04014//Ras signaling pathway;ko04270//Vascular smooth muscle contraction;ko04972//Pancreatic secretion;ko00564//Glycerophospholipid metabolism;ko00590//Arachidonic acid metabolism;ko00565//Ether lipid metabolism;ko04975//Fat digestion and absorption;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047;K01047	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response;GO:0016042//lipid catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0046470//phosphatidylcholine metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0050482//arachidonic acid secretion	--
ENSG00000188785	3.635	4.629	2.515	4.108	3.519	5.333	296	290	192.13	181	228.11	216	ZNF548	zinc finger protein 548 [Source:HGNC Symbol;Acc:HGNC:26561]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188786	2.618	2.84	2.459	2.247	2.459	2.73	431	470	299	274	342	327	MTF1	metal regulatory transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:7428]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035035//histone acetyltransferase binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006979//response to oxidative stress;GO:0007417//central nervous system development;GO:0010038//response to metal ion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046686//response to cadmium ion;GO:0071294//cellular response to zinc ion;GO:1990079//cartilage homeostasis"	zf-C2H2
ENSG00000188800	0	0	0	0	0	0	0	0	0	0	0	0	TMCO2	transmembrane and coiled-coil domains 2 [Source:HGNC Symbol;Acc:HGNC:23312]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000188803	0	0	0	0	0	0	0	0	0	0	0	0	SHISA6	shisa family member 6 [Source:HGNC Symbol;Acc:HGNC:34491]	-	-	-	-	"GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0032591//dendritic spine membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099061//integral component of postsynaptic density membrane"	GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0035255//ionotropic glutamate receptor binding	GO:0007283//spermatogenesis;GO:0016055//Wnt signaling pathway;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:0098970//postsynaptic neurotransmitter receptor diffusion trapping;GO:0098976//excitatory chemical synaptic transmission;GO:1904717//regulation of AMPA glutamate receptor clustering;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000188807	8.596	8.889	10.037	13.534	11.531	12.33	667	712	591	799	776	715	TMEM201	transmembrane protein 201 [Source:HGNC Symbol;Acc:HGNC:33719]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031616//spindle pole centrosome;GO:0031965//nuclear membrane;GO:0032541//cortical endoplasmic reticulum	GO:0005515//protein binding;GO:0005521//lamin binding;GO:0051015//actin filament binding	GO:0006998//nuclear envelope organization;GO:0007097//nuclear migration;GO:0010761//fibroblast migration;GO:0030473//nuclear migration along microtubule;GO:0051642//centrosome localization;GO:0090435//protein localization to nuclear envelope	--
ENSG00000188811	6.143	6.438	6.681	5.541	6.356	5.95	424	450	343	285	373	301	NHLRC3	NHL repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:33751]	-	-	-	-	GO:0005576//extracellular region;GO:0035578//azurophil granule lumen	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000188816	0	0	0	0.081	0	0	0	0	0	2	0	0	HMX2	H6 family homeobox 2 [Source:HGNC Symbol;Acc:HGNC:5018]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0042472//inner ear morphogenesis;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	Homeobox
ENSG00000188817	0.031	0	0	0	0	0	1	0	0	0	0	0	SNTN	"sentan, cilia apical structure protein [Source:HGNC Symbol;Acc:HGNC:33706]"	-	-	-	-	GO:0005929//cilium;GO:0042995//cell projection	GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000188818	1.307	0.965	1.263	1.575	1.661	1.958	51	39.13	35	46.58	52.38	65	ZDHHC11	zinc finger DHHC-type containing 11 [Source:HGNC Symbol;Acc:HGNC:19158]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0035591//signaling adaptor activity	GO:0002230//positive regulation of defense response to virus by host;GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0140374//antiviral innate immune response	--
ENSG00000188820	0	0	0	0.504	0.211	0	0	0	0	7	2	0	CALHM6	calcium homeostasis modulator family member 6 [Source:HGNC Symbol;Acc:HGNC:33391]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005261//cation channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000188822	0	0	0	0	0	0	0	0	0	0	0	0	CNR2	cannabinoid receptor 2 [Source:HGNC Symbol;Acc:HGNC:2160]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04278	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon	GO:0004930//G protein-coupled receptor activity;GO:0004949//cannabinoid receptor activity;GO:0005515//protein binding	"GO:0001975//response to amphetamine;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0019233//sensory perception of pain;GO:0030595//leukocyte chemotaxis;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0032496//response to lipopolysaccharide;GO:0033004//negative regulation of mast cell activation;GO:0038171//cannabinoid signaling pathway;GO:0045759//negative regulation of action potential;GO:0050728//negative regulation of inflammatory response;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051716//cellular response to stimulus"	--
ENSG00000188827	1.621	1.928	2.16	1.699	1.88	1.748	246	294	242	191	241	193	SLX4	SLX4 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:23845]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10484	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0033557//Slx1-Slx4 complex;GO:0048476//Holliday junction resolvase complex;GO:0070522//ERCC4-ERCC1 complex"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0046872//metal ion binding	GO:0000706//meiotic DNA double-strand break processing;GO:0000712//resolution of meiotic recombination intermediates;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0032206//positive regulation of telomere maintenance;GO:0036297//interstrand cross-link repair;GO:0050790//regulation of catalytic activity;GO:0061820//telomeric D-loop disassembly;GO:0072429//response to intra-S DNA damage checkpoint signaling;GO:0090656//t-circle formation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904431//positive regulation of t-circle formation	--
ENSG00000188833	11.591	13.503	9.881	9.936	13.223	10.683	510	575	311	320	466	338	ENTPD8	ectonucleoside triphosphate diphosphohydrolase 8 [Source:HGNC Symbol;Acc:HGNC:24860]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Infectious disease: viral;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko05169//Epstein-Barr virus infection;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01510;K01510;K01510;K01510	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:0046872//metal ion binding;GO:0102485//dATP phosphohydrolase activity;GO:0102486//dCTP phosphohydrolase activity;GO:0102487//dUTP phosphohydrolase activity;GO:0102488//dTTP phosphohydrolase activity;GO:0102489//GTP phosphohydrolase activity;GO:0102490//8-oxo-dGTP phosphohydrolase activity;GO:0102491//dGTP phosphohydrolase activity	GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009133//nucleoside diphosphate biosynthetic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process	--
ENSG00000188846	213.831	214.34	205.544	184.888	160.941	165.086	5384	5549	3871	3478	3683	3037	RPL14	ribosomal protein L14 [Source:HGNC Symbol;Acc:HGNC:10305]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02875;K02875	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000188848	0.765	0.723	0.393	0.045	0.119	0.091	138	130	52	6	18	12	BEND4	BEN domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23815]	-	-	-	-	-	GO:0003677//DNA binding	-	--
ENSG00000188859	9.827	9.697	7.255	4.813	4.583	5.921	613	595	357	213	250	276	FAM78B	family with sequence similarity 78 member B [Source:HGNC Symbol;Acc:HGNC:13495]	-	-	-	-	-	-	-	--
ENSG00000188868	1.208	1.299	1.575	0.526	1.099	1.157	37	35	34	13	23	21	ZNF563	zinc finger protein 563 [Source:HGNC Symbol;Acc:HGNC:30498]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000188869	0.374	0.46	0.112	0.182	0.467	0.425	37	45	8	13	39	30	TMC3	transmembrane channel like 3 [Source:HGNC Symbol;Acc:HGNC:22995]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008381//mechanosensitive ion channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport	--
ENSG00000188877	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000188878	1.748	2.631	2.726	2.108	2.34	2.175	138	196	161	132	141	124	FBF1	Fas binding factor 1 [Source:HGNC Symbol;Acc:HGNC:24674]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0036064//ciliary basal body;GO:0043296//apical junction complex;GO:0045095//keratin filament;GO:0097539//ciliary transition fiber	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0043297//apical junction assembly;GO:0060271//cilium assembly;GO:0090162//establishment of epithelial cell polarity	--
ENSG00000188883	0.126	0.067	0	0.151	0.172	0.257	3	3	0	5	5	6	KLRG2	killer cell lectin like receptor G2 [Source:HGNC Symbol;Acc:HGNC:24778]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding	-	--
ENSG00000188886	0	0.04	0	0.136	0.048	0	0	2	0	5	2	0	ASTL	astacin like metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:31704]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0060473//cortical granule	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070001//aspartic-type peptidase activity;GO:0070002//glutamic-type peptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0009566//fertilization;GO:0010954//positive regulation of protein processing;GO:0060468//prevention of polyspermy;GO:2000360//negative regulation of binding of sperm to zona pellucida	--
ENSG00000188895	28.053	26.79	29.289	24.626	26.049	29.257	1646	1544	1251	1122	1297	1252	MSL1	MSL complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:27905]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0072487//MSL complex	GO:0003682//chromatin binding;GO:0005515//protein binding	"GO:0006325//chromatin organization;GO:0043984//histone H4-K16 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000188897	0.414	0.291	0.253	0.772	0.199	1.033	51	58	41	63	37	76	apolpp	novel lipoprotein amino terminal region containing protein	-	-	-	-	-	GO:0005319//lipid transporter activity	GO:0006869//lipid transport;GO:0032355//response to estradiol;GO:0071391//cellular response to estrogen stimulus	--
ENSG00000188906	0.521	0.332	0.374	0.351	0.521	0.51	67	45	38	26	56	54	LRRK2	leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K08844;K08844	"GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016234//inclusion body;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0032473//cytoplasmic side of mitochondrial outer membrane;GO:0032839//dendrite cytoplasm;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043204//perikaryon;GO:0043231//intracellular membrane-bounded organelle;GO:0044753//amphisome;GO:0044754//autolysosome;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0070971//endoplasmic reticulum exit site;GO:0097487//multivesicular body, internal vesicle;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0099400//caveola neck;GO:0099523//presynaptic cytosol;GO:1990904//ribonucleoprotein complex;GO:1990909//Wnt signalosome"	GO:0000149//SNARE binding;GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003779//actin binding;GO:0003924//GTPase activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0017075//syntaxin-1 binding;GO:0030159//signaling receptor complex adaptor activity;GO:0030276//clathrin binding;GO:0031267//small GTPase binding;GO:0034211//GTP-dependent protein kinase activity;GO:0036479//peroxidase inhibitor activity;GO:0039706//co-receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0051018//protein kinase A binding;GO:0106310//protein serine kinase activity;GO:1904713//beta-catenin destruction complex binding	"GO:0000165//MAPK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0006606//protein import into nucleus;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0006979//response to oxidative stress;GO:0007005//mitochondrion organization;GO:0007029//endoplasmic reticulum organization;GO:0007030//Golgi organization;GO:0007040//lysosome organization;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0007283//spermatogenesis;GO:0007528//neuromuscular junction development;GO:0008340//determination of adult lifespan;GO:0009267//cellular response to starvation;GO:0010468//regulation of gene expression;GO:0010506//regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0010738//regulation of protein kinase A signaling;GO:0010955//negative regulation of protein processing;GO:0010977//negative regulation of neuron projection development;GO:0014041//regulation of neuron maturation;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019722//calcium-mediated signaling;GO:0021756//striatum development;GO:0021772//olfactory bulb development;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0030154//cell differentiation;GO:0030162//regulation of proteolysis;GO:0031331//positive regulation of cellular catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:0032092//positive regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034260//negative regulation of GTPase activity;GO:0034599//cellular response to oxidative stress;GO:0034613//cellular protein localization;GO:0035556//intracellular signal transduction;GO:0035564//regulation of kidney size;GO:0035640//exploration behavior;GO:0035641//locomotory exploration behavior;GO:0035751//regulation of lysosomal lumen pH;GO:0040012//regulation of locomotion;GO:0042391//regulation of membrane potential;GO:0043068//positive regulation of programmed cell death;GO:0043406//positive regulation of MAP kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0046039//GTP metabolic process;GO:0046777//protein autophosphorylation;GO:0048312//intracellular distribution of mitochondria;GO:0048812//neuron projection morphogenesis;GO:0051646//mitochondrion localization;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0051900//regulation of mitochondrial depolarization;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060070//canonical Wnt signaling pathway;GO:0060079//excitatory postsynaptic potential;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0061001//regulation of dendritic spine morphogenesis;GO:0070585//protein localization to mitochondrion;GO:0070973//protein localization to endoplasmic reticulum exit site;GO:0070997//neuron death;GO:0071287//cellular response to manganese ion;GO:0071407//cellular response to organic cyclic compound;GO:0072593//reactive oxygen species metabolic process;GO:0090140//regulation of mitochondrial fission;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:0140058//neuron projection arborization;GO:1900242//regulation of synaptic vesicle endocytosis;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:1901214//regulation of neuron death;GO:1901215//negative regulation of neuron death;GO:1901727//positive regulation of histone deacetylase activity;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902499//positive regulation of protein autoubiquitination;GO:1902692//regulation of neuroblast proliferation;GO:1902803//regulation of synaptic vesicle transport;GO:1902823//negative regulation of late endosome to lysosome transport;GO:1902902//negative regulation of autophagosome assembly;GO:1903125//negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:1903215//negative regulation of protein targeting to mitochondrion;GO:1903217//negative regulation of protein processing involved in protein targeting to mitochondrion;GO:1903351//cellular response to dopamine;GO:1903980//positive regulation of microglial cell activation;GO:1904887//Wnt signalosome assembly;GO:1905279//regulation of retrograde transport, endosome to Golgi;GO:1905289//regulation of CAMKK-AMPK signaling cascade;GO:2000172//regulation of branching morphogenesis of a nerve;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000469//negative regulation of peroxidase activity"	--
ENSG00000188909	0	0	0	0	0	0	0	0	0	0	0	0	BSX	brain specific homeobox [Source:HGNC Symbol;Acc:HGNC:20450]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007626//locomotory behavior;GO:0042755//eating behavior;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060056//mammary gland involution"	Homeobox
ENSG00000188910	0	0	0.03	0	0	0.091	0	0	1	0	0	3	GJB3	gap junction protein beta 3 [Source:HGNC Symbol;Acc:HGNC:4285]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	GO:0005243//gap junction channel activity;GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001890//placenta development;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0043588//skin development;GO:0055085//transmembrane transport;GO:0071300//cellular response to retinoic acid	--
ENSG00000188916	0.112	0.179	0.084	0.191	0.223	0.105	11	18	5	12	17	5	INSYN2A	inhibitory synaptic factor 2A [Source:HGNC Symbol;Acc:HGNC:33859]	-	-	-	-	GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	GO:0060080//inhibitory postsynaptic potential	--
ENSG00000188917	4.555	5.106	4.613	3.825	4.218	4.777	296	333	224	188	231	225	TRMT2B	tRNA methyltransferase 2 homolog B [Source:HGNC Symbol;Acc:HGNC:25748]	-	-	-	-	-	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity;GO:0030697//S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	GO:0001510//RNA methylation;GO:0006396//RNA processing;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000188921	0.419	0.33	0.371	0.385	0.427	0.52	72	57	47	49	62	65	HACD4	3-hydroxyacyl-CoA dehydratase 4 [Source:HGNC Symbol;Acc:HGNC:20920]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10703;K10703;K10703;K10703	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0016829//lyase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0042761//very long-chain fatty acid biosynthetic process	--
ENSG00000188931	2.118	2.479	2.867	1.598	0.811	0.428	34	40	34	19	11	5	CFAP126	cilia and flagella associated protein 126 [Source:HGNC Symbol;Acc:HGNC:32325]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0036064//ciliary basal body;GO:0042995//cell projection	-	GO:0030030//cell projection organization;GO:0044782//cilium organization	--
ENSG00000188937	3.79	3.862	5.267	5.653	5.895	5.654	193	195	197	211	252	206	NYX	nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007601//visual perception;GO:0008150//biological_process;GO:0050896//response to stimulus	--
ENSG00000188938	27.959	27.944	25.916	28.058	24.496	27.356	1151.07	1153.14	815.16	850	872	791	FAM120AOS	family with sequence similarity 120A opposite strand [Source:HGNC Symbol;Acc:HGNC:23389]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000188958	0	0.069	0.027	0	0.048	0	0	2	1	0	2	0	UTS2B	urotensin 2B [Source:HGNC Symbol;Acc:HGNC:30894]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K24267	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0097746//blood vessel diameter maintenance	--
ENSG00000188959	0	0	0	0	0	0	0	0	0	0	0	0	C9orf152	chromosome 9 open reading frame 152 [Source:HGNC Symbol;Acc:HGNC:31455]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000188976	20.194	22.222	22.518	25.614	24.964	20.52	1154.8	1277.31	951.07	1085	1206.1	853.82	NOC2L	NOC2 like nucleolar associated transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:24517]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030690//Noc1p-Noc2p complex;GO:0030691//Noc2p-Noc3p complex	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002903//negative regulation of B cell apoptotic process;GO:0006915//apoptotic process;GO:0031497//chromatin assembly;GO:0034644//cellular response to UV;GO:0035067//negative regulation of histone acetylation;GO:0042273//ribosomal large subunit biogenesis;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000188981	0	0.062	0	0	0	0	0	2	0	0	0	0	MSANTD1	Myb/SANT DNA binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33741]	-	-	-	-	GO:0016604//nuclear body	-	"GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000188984	0	0	0	0	0	0	0	0	0	0	0	0	AADACL3	arylacetamide deacetylase like 3 [Source:HGNC Symbol;Acc:HGNC:32037]	-	-	-	-	GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	-	--
ENSG00000188986	16.931	18.128	17.116	18.885	20.804	16.043	892	960	666	737	926	615	NELFB	negative elongation factor complex member B [Source:HGNC Symbol;Acc:HGNC:24324]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032021//NELF complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0008283//cell population proliferation;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048863//stem cell differentiation;GO:2000737//negative regulation of stem cell differentiation"	--
ENSG00000188991	0	0	0	0	0	0	0	0	0	0	0	0	SLC15A5	solute carrier family 15 member 5 [Source:HGNC Symbol;Acc:HGNC:33455]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0022857//transmembrane transporter activity	GO:0015031//protein transport;GO:0015833//peptide transport;GO:0055085//transmembrane transport	--
ENSG00000188992	0	0	0	0	0	0	0	0	0	0	0	0	LIPI	lipase I [Source:HGNC Symbol;Acc:HGNC:18821]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity;GO:0008201//heparin binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0019433//triglyceride catabolic process	--
ENSG00000188993	0.029	0.014	0	0.02	0	0	2	1	0	1	0	0	LRRC66	leucine rich repeat containing 66 [Source:HGNC Symbol;Acc:HGNC:34299]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000188994	4.226	2.595	1.887	1.179	2.091	2.144	848	406	283	181	363	311	ZNF292	zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000188996	0	0.041	0	0	0	0	0	1	0	0	0	0	HUS1B	HUS1 checkpoint clamp component B [Source:HGNC Symbol;Acc:HGNC:16485]	-	-	-	-	GO:0005730//nucleolus;GO:0030896//checkpoint clamp complex;GO:0035861//site of double-strand break	-	GO:0000077//DNA damage checkpoint signaling;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0006289//nucleotide-excision repair;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0044778//meiotic DNA integrity checkpoint signaling	--
ENSG00000188997	6.148	5.675	5.99	5.859	5.725	7.101	415	401	311	261	340	316	KCTD21	potassium channel tetramerization domain containing 21 [Source:HGNC Symbol;Acc:HGNC:27452]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding;GO:0097602//cullin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0040008//regulation of growth;GO:0045879//negative regulation of smoothened signaling pathway;GO:0051260//protein homooligomerization	--
ENSG00000189001	0.05	0	0.082	0	0.059	0.208	1	0	2	0	2	3	SBSN	suprabasin [Source:HGNC Symbol;Acc:HGNC:24950]	-	-	-	-	GO:0005576//extracellular region;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000189007	0.466	0.315	0.34	0.254	0.406	0.541	61	41	33	26	45	52	ADAT2	adenosine deaminase tRNA specific 2 [Source:HGNC Symbol;Acc:HGNC:21172]	-	-	-	-	GO:0005654//nucleoplasm	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0052717//tRNA-specific adenosine-34 deaminase activity	GO:0002100//tRNA wobble adenosine to inosine editing;GO:0008033//tRNA processing	--
ENSG00000189013	0	0	0	0	0	0	0	0	0	0	0	0	KIR2DL4	"killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 [Source:HGNC Symbol;Acc:HGNC:6332]"	Cellular Processes;Organismal Systems	Cell growth and death;Immune system	ko04218//Cellular senescence;ko04612//Antigen processing and presentation	K24231;K24231	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0032394//MHC class Ib receptor activity	GO:0002729//positive regulation of natural killer cell cytokine production;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:2000774//positive regulation of cellular senescence	--
ENSG00000189023	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB16	MAGE family member B16 [Source:HGNC Symbol;Acc:HGNC:21188]	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000189030	0	0	0	0.095	0	0	0	0	0	1	0	0	VHLL	VHL like [Source:HGNC Symbol;Acc:HGNC:30666]	Human Diseases;Genetic Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	"Cancer: overview;Folding, sorting and degradation;Signal transduction;Cancer: specific types;Aging"	ko05200//Pathways in cancer;ko04120//Ubiquitin mediated proteolysis;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma;ko04212//Longevity regulating pathway - worm	K03871;K03871;K03871;K03871;K03871	-	GO:0005515//protein binding	-	--
ENSG00000189037	0	0	0	0	0	0	0	0	0	0	0	0	DUSP21	dual specificity phosphatase 21 [Source:HGNC Symbol;Acc:HGNC:20476]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000189042	2.577	2.047	1.601	1.174	1.742	1.658	126	117	65	42	84	66	ZNF567	zinc finger protein 567 [Source:HGNC Symbol;Acc:HGNC:28696]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189043	27.387	27.883	27.137	35.182	22.91	27.025	1156	1183	846	1100	817	830	NDUFA4	NDUFA4 mitochondrial complex associated [Source:HGNC Symbol;Acc:HGNC:7687]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948;K03948	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0044877//protein-containing complex binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:1904960//positive regulation of cytochrome-c oxidase activity"	--
ENSG00000189045	0	0.122	0	0	0.048	0.132	0	3	0	0	1	2	ANKDD1B	ankyrin repeat and death domain containing 1B [Source:HGNC Symbol;Acc:HGNC:32525]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000189046	8.072	6.577	6.846	8.839	7.519	6.62	164	147	111	134	132	107	ALKBH2	"alkB homolog 2, alpha-ketoglutarate dependent dioxygenase [Source:HGNC Symbol;Acc:HGNC:32487]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0035516//oxidative DNA demethylase activity;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0051747//cytosine C-5 DNA demethylase activity	GO:0006281//DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0035511//oxidative DNA demethylation;GO:0070989//oxidative demethylation;GO:0080111//DNA demethylation	--
ENSG00000189050	7.147	5.339	6.378	4.78	5.616	5.942	289	232	203	152	193	185	RNFT1	"ring finger protein, transmembrane 1 [Source:HGNC Symbol;Acc:HGNC:30206]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:1904294//positive regulation of ERAD pathway	--
ENSG00000189051	0	0	0	0	0	0	0	0	0	0	0	0	RNF222	ring finger protein 222 [Source:HGNC Symbol;Acc:HGNC:34517]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding	-	--
ENSG00000189052	0	0	0	0	0	0	0	0	0	0	0	0	CGB5	chorionic gonadotropin subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:16452]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0061696//pituitary gonadotropin complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0009755//hormone-mediated signaling pathway	--
ENSG00000189056	57.17	62.171	60.786	65.526	71.674	58.937	13481	14917	10554	11602	14361	10164	RELN	reelin [Source:HGNC Symbol;Acc:HGNC:9957]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Neurodegenerative disease;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05017//Spinocerebellar ataxia;ko04512//ECM-receptor interaction	K06249;K06249;K06249;K06249;K06249	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0031012//extracellular matrix;GO:0043005//neuron projection;GO:0110157//reelin complex	GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070325//lipoprotein particle receptor binding;GO:0070326//very-low-density lipoprotein particle receptor binding	"GO:0000904//cell morphogenesis involved in differentiation;GO:0001764//neuron migration;GO:0001934//positive regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0007612//learning;GO:0007616//long-term memory;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0010001//glial cell differentiation;GO:0010468//regulation of gene expression;GO:0010976//positive regulation of neuron projection development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0021511//spinal cord patterning;GO:0021517//ventral spinal cord development;GO:0021766//hippocampus development;GO:0021800//cerebral cortex tangential migration;GO:0021819//layer formation in cerebral cortex;GO:0021987//cerebral cortex development;GO:0030900//forebrain development;GO:0032008//positive regulation of TOR signaling;GO:0032793//positive regulation of CREB transcription factor activity;GO:0035418//protein localization to synapse;GO:0038026//reelin-mediated signaling pathway;GO:0045664//regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0048265//response to pain;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050795//regulation of behavior;GO:0050804//modulation of chemical synaptic transmission;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060025//regulation of synaptic activity;GO:0060291//long-term synaptic potentiation;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0090129//positive regulation of synapse maturation;GO:0097114//NMDA glutamate receptor clustering;GO:0097119//postsynaptic density protein 95 clustering;GO:0097120//receptor localization to synapse;GO:0097477//lateral motor column neuron migration;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1902078//positive regulation of lateral motor column neuron migration;GO:2000310//regulation of NMDA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000969//positive regulation of AMPA receptor activity;GO:2001222//regulation of neuron migration"	--
ENSG00000189057	0.154	0.056	0.249	0.039	0.048	0.028	4	4	9	2	2	1	FAM111B	FAM111 trypsin like peptidase B [Source:HGNC Symbol;Acc:HGNC:24200]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006260//DNA replication;GO:0006508//proteolysis	--
ENSG00000189058	0	0	0	0	0.397	0	0	0	0	0	6	0	APOD	apolipoprotein D [Source:HGNC Symbol;Acc:HGNC:612]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0022626//cytosolic ribosome;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005319//lipid transporter activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0015485//cholesterol binding	GO:0000302//response to reactive oxygen species;GO:0001525//angiogenesis;GO:0006006//glucose metabolic process;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0007420//brain development;GO:0007568//aging;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0014012//peripheral nervous system axon regeneration;GO:0042246//tissue regeneration;GO:0042308//negative regulation of protein import into nucleus;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048678//response to axon injury;GO:0051895//negative regulation of focal adhesion assembly;GO:0060588//negative regulation of lipoprotein lipid oxidation;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:2000405//negative regulation of T cell migration	--
ENSG00000189060	26.381	25.005	27.1	25.781	25.166	33.22	1206	1149	915	873	972	1105	H1-0	H1.0 linker histone [Source:HGNC Symbol;Acc:HGNC:4714]	-	-	-	-	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0015629//actin cytoskeleton;GO:0016604//nuclear body;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0031492//nucleosomal DNA binding	GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning;GO:0030261//chromosome condensation;GO:0031507//heterochromatin assembly;GO:0045910//negative regulation of DNA recombination;GO:2000679//positive regulation of transcription regulatory region DNA binding	--
ENSG00000189064	0	0	0	0	0	0	0	0	0	0	0	0	GAGE2A	G antigen 2A [Source:HGNC Symbol;Acc:HGNC:4099]	-	-	-	-	-	-	-	--
ENSG00000189067	65.631	66.897	70.076	61.456	64.319	74.109	2470	2464	1919	1734	1960	1983	LITAF	lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K19363	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0098559//cytoplasmic side of early endosome membrane;GO:0098560//cytoplasmic side of late endosome membrane;GO:0098574//cytoplasmic side of lysosomal membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0050699//WW domain binding"	GO:0001817//regulation of cytokine production;GO:0032496//response to lipopolysaccharide;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071222//cellular response to lipopolysaccharide;GO:1901223//negative regulation of NIK/NF-kappaB signaling	zf-LITAF-like
ENSG00000189068	0	0	0	0	0	0	0	0	0	0	0	0	VSTM1	V-set and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29455]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0007165//signal transduction	--
ENSG00000189077	19.889	22.019	21.945	26.831	24.503	23.835	549	616	451	564	571	483	TMEM120A	transmembrane protein 120A [Source:HGNC Symbol;Acc:HGNC:21697]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005216//ion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0045444//fat cell differentiation;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization	--
ENSG00000189079	6.177	5.55	5.152	3.637	4.32	4.174	967	827	562	401	558	459	ARID2	AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037]	Human Diseases	Cancer: specific types	ko05225//Hepatocellular carcinoma	K11765	GO:0000776//kinetochore;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0016514//SWI/SNF complex;GO:0016586//RSC-type complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0003007//heart morphogenesis;GO:0006325//chromatin organization;GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0030336//negative regulation of cell migration;GO:0042592//homeostatic process;GO:0045582//positive regulation of T cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0048568//embryonic organ development;GO:0060038//cardiac muscle cell proliferation;GO:0060982//coronary artery morphogenesis;GO:0070316//regulation of G0 to G1 transition;GO:0072359//circulatory system development;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	ARID
ENSG00000189090	0	0	0	0	0	0	0	0	0	0	0	0	FAM25G	family with sequence similarity 25 member G [Source:HGNC Symbol;Acc:HGNC:23590]	-	-	-	-	-	-	-	--
ENSG00000189091	26.766	25.776	24.413	27.215	27.415	25.486	4676	5148	3581	3680	4193	3360	SF3B3	splicing factor 3b subunit 3 [Source:HGNC Symbol;Acc:HGNC:10770]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12830	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus;GO:0071005//U2-type precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0030620//U2 snRNA binding;GO:0044877//protein-containing complex binding	"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006282//regulation of DNA repair;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042177//negative regulation of protein catabolic process;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000189099	0	0	0	0	0	0	0	0	0	0	0	0	PRSS48	serine protease 48 [Source:HGNC Symbol;Acc:HGNC:24635]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000189108	0	0	0	0	0	0	0	0	0	0	0	0	IL1RAPL2	interleukin 1 receptor accessory protein like 2 [Source:HGNC Symbol;Acc:HGNC:5997]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	"GO:0003953//NAD+ nucleosidase activity;GO:0004908//interleukin-1 receptor activity;GO:0004910//interleukin-1, type II, blocking receptor activity;GO:0016787//hydrolase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0019221//cytokine-mediated signaling pathway;GO:0071345//cellular response to cytokine stimulus;GO:1905606//regulation of presynapse assembly	--
ENSG00000189114	4.163	4.401	3.849	4.567	3.61	4.812	191	235	151	171	162	186	BLOC1S3	biogenesis of lysosomal organelles complex 1 subunit 3 [Source:HGNC Symbol;Acc:HGNC:20914]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex;GO:1904115//axon cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity	GO:0001654//eye development;GO:0007596//blood coagulation;GO:0008089//anterograde axonal transport;GO:0009410//response to xenobiotic stimulus;GO:0030168//platelet activation;GO:0031175//neuron projection development;GO:0032402//melanosome transport;GO:0032438//melanosome organization;GO:0032816//positive regulation of natural killer cell activation;GO:0033299//secretion of lysosomal enzymes;GO:0035646//endosome to melanosome transport;GO:0043473//pigmentation;GO:0048066//developmental pigmentation;GO:0048490//anterograde synaptic vesicle transport;GO:0060155//platelet dense granule organization;GO:0071806//protein transmembrane transport	--
ENSG00000189120	0.051	0	0	0	0.06	0	4	0	0	0	4	0	SP6	Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0042481//regulation of odontogenesis	zf-C2H2
ENSG00000189127	0	0	0	0.017	0	0.036	0	0	0	1	0	2	ANKRD34B	ankyrin repeat domain 34B [Source:HGNC Symbol;Acc:HGNC:33736]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000189129	66.767	67.248	66.632	59.963	53.795	40.728	795	799	580	521	529	339	PLAC9	placenta associated 9 [Source:HGNC Symbol;Acc:HGNC:19255]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000189132	0	0	0	0	0	0	0	0	0	0	0	0	FAM47B	family with sequence similarity 47 member B [Source:HGNC Symbol;Acc:HGNC:26659]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189134	0	0.029	0	0	0	0	0	1	0	0	0	0	NKAPL	NFKB activating protein like [Source:HGNC Symbol;Acc:HGNC:21584]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation	--
ENSG00000189139	0	0	0	0	0	0	0	0	0	0	0	0	FSCB	fibrous sheath CABYR binding protein [Source:HGNC Symbol;Acc:HGNC:20494]	-	-	-	-	GO:0005929//cilium;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005509//calcium ion binding	GO:0033234//negative regulation of protein sumoylation	--
ENSG00000189143	0.292	0.257	0.585	0.409	0.768	0.404	24	22	16	15	27	12	CLDN4	claudin 4 [Source:HGNC Symbol;Acc:HGNC:2046]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0070160//tight junction	GO:0004888//transmembrane signaling receptor activity;GO:0005198//structural molecule activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007155//cell adhesion;GO:0007565//female pregnancy;GO:0007623//circadian rhythm;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0022604//regulation of cell morphogenesis;GO:0030335//positive regulation of cell migration;GO:0032570//response to progesterone;GO:0061436//establishment of skin barrier;GO:0070293//renal absorption;GO:0070830//bicellular tight junction assembly;GO:0090303//positive regulation of wound healing;GO:1905050//positive regulation of metallopeptidase activity	--
ENSG00000189144	0.76	0.579	0.869	0.455	0.59	1.726	26	18	23	10	13	22	ZNF573	zinc finger protein 573 [Source:HGNC Symbol;Acc:HGNC:26420]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189152	0	0.167	0	0	0	0	0	2	0	0	0	0	GRAPL	GRB2 related adaptor protein like [Source:HGNC Symbol;Acc:HGNC:37240]	-	-	-	-	-	GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity	GO:0007165//signal transduction;GO:0016477//cell migration	--
ENSG00000189157	1.278	0.864	1.844	1.1	0.87	1.324	54.43	29.27	49	28	24.04	39	FAM47E	family with sequence similarity 47 member E [Source:HGNC Symbol;Acc:HGNC:34343]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008047//enzyme activator activity	"GO:0006325//chromatin organization;GO:0031062//positive regulation of histone methylation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0050790//regulation of catalytic activity;GO:0071168//protein localization to chromatin"	--
ENSG00000189159	16.196	16.333	17.869	21.151	18.455	15.471	381	376	306	362	362	287	JPT1	Jupiter microtubule associated homolog 1 [Source:HGNC Symbol;Acc:HGNC:14569]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane	GO:0005515//protein binding	-	--
ENSG00000189164	1.695	1.822	2.186	1.285	2.877	1.98	163	123	104	72	109	100	ZNF527	zinc finger protein 527 [Source:HGNC Symbol;Acc:HGNC:29385]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189167	0.131	0	0	0	0	0	3	0	0	0	0	0	ZAR1L	zygote arrest 1 like [Source:HGNC Symbol;Acc:HGNC:37116]	-	-	-	-	GO:0005737//cytoplasm	GO:1903231//mRNA binding involved in posttranscriptional gene silencing	GO:0006412//translation;GO:0016441//posttranscriptional gene silencing	--
ENSG00000189169	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-12	keratin associated protein 10-12 [Source:HGNC Symbol;Acc:HGNC:20533]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0031424//keratinization	--
ENSG00000189171	37.688	37.79	41.606	31.488	25.925	29.078	390	399	320	250	234	223	S100A13	S100 calcium binding protein A13 [Source:HGNC Symbol;Acc:HGNC:10490]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008289//lipid binding;GO:0017134//fibroblast growth factor binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050786//RAGE receptor binding	GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell population proliferation;GO:0015031//protein transport;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043303//mast cell degranulation	--
ENSG00000189180	5.92	4.983	4.772	3.27	3.674	4.519	731	527	355	229	375.55	333.02	ZNF33A	zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189181	0	0	0	0	0	0	0	0	0	0	0	0	OR14I1	olfactory receptor family 14 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:19575]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000189182	0	0	0	0	0	0	0	0	0	0	0	0	KRT77	keratin 77 [Source:HGNC Symbol;Acc:HGNC:20411]	-	-	-	-	GO:0001533//cornified envelope;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000189184	48.002	47.716	45.457	31.669	38.351	40.135	4812	4868	3326	2464	3160	2788	PCDH18	protocadherin 18 [Source:HGNC Symbol;Acc:HGNC:14268]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007420//brain development	--
ENSG00000189186	0.028	0.024	0	0	0	0	2	1	0	0	0	0	DCAF8L2	DDB1 and CUL4 associated factor 8 like 2 [Source:HGNC Symbol;Acc:HGNC:31811]	-	-	-	-	GO:0005737//cytoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	-	--
ENSG00000189190	0.831	0.736	0.901	0.725	0.767	0.674	62	48	43	35.6	40	36	ZNF600	zinc finger protein 600 [Source:HGNC Symbol;Acc:HGNC:30951]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189195	0.929	0.657	0.492	0.517	0.278	0.539	108	53	28	34	26	44	BTBD8	BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:21019]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030122//AP-2 adaptor complex;GO:0030136//clathrin-coated vesicle;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0044297//cell body;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0098793//presynapse	GO:0005515//protein binding	GO:0006897//endocytosis;GO:0031175//neuron projection development;GO:0036466//synaptic vesicle recycling via endosome;GO:0150007//clathrin-dependent synaptic vesicle endocytosis	--
ENSG00000189221	2.886	2.605	3.904	3.654	4.046	4.282	238	220	239	221	285	258	MAOA	monoamine oxidase A [Source:HGNC Symbol;Acc:HGNC:6833]	Metabolism;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Human Diseases;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Substance dependence;Nervous system;Nervous system;Xenobiotics biodegradation and metabolism;Substance dependence;Amino acid metabolism;Substance dependence;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko05012//Parkinson disease;ko05034//Alcoholism;ko04728//Dopaminergic synapse;ko04726//Serotonergic synapse;ko00982//Drug metabolism - cytochrome P450;ko05031//Amphetamine addiction;ko00330//Arginine and proline metabolism;ko05030//Cocaine addiction;ko00380//Tryptophan metabolism;ko00260//Glycine, serine and threonine metabolism;ko00350//Tyrosine metabolism;ko00340//Histidine metabolism;ko00360//Phenylalanine metabolism"	K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274;K00274	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008131//primary amine oxidase activity;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0097621//monoamine oxidase activity	GO:0006576//cellular biogenic amine metabolic process;GO:0006584//catecholamine metabolic process;GO:0009967//positive regulation of signal transduction;GO:0042135//neurotransmitter catabolic process;GO:0042420//dopamine catabolic process	--
ENSG00000189227	1.472	0.927	1.121	1.397	1.456	1.327	107	81	72	90	107	84	C15orf61	chromosome 15 open reading frame 61 [Source:HGNC Symbol;Acc:HGNC:34453]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000189233	0	0	0	0	0	0	0	0	0	0	0	0	NUGGC	"nuclear GTPase, germinal center associated [Source:HGNC Symbol;Acc:HGNC:33550]"	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0043066//negative regulation of apoptotic process;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000189241	20.953	22.55	23.651	23.549	22.658	25.535	2205	2386	1838	1836	2015	1955	TSPYL1	TSPY like 1 [Source:HGNC Symbol;Acc:HGNC:12382]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0008150//biological_process	--
ENSG00000189252	0	0	0	0	0	0	0	0	0	0	0	0	SPANXN3	SPANX family member N3 [Source:HGNC Symbol;Acc:HGNC:33176]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189253	0	0	0	0	0	0	0	0	0	0	0	0	TRIM64B	tripartite motif containing 64B [Source:HGNC Symbol;Acc:HGNC:37147]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000189266	62.691	57.706	62.215	59.714	54.2	61.832	2748	2549	2019	1909	1910	2012	PNRC2	proline rich nuclear receptor coactivator 2 [Source:HGNC Symbol;Acc:HGNC:23158]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA"	--
ENSG00000189269	0.379	0.111	0.301	0.22	0.176	0.193	6	3	6	3	4	2	DRICH1	aspartate rich 1 [Source:HGNC Symbol;Acc:HGNC:28031]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189280	0	0	0.096	0.144	0.042	0	0	0	2	3	1	0	GJB5	gap junction protein beta 5 [Source:HGNC Symbol;Acc:HGNC:4287]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0005515//protein binding	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0008544//epidermis development;GO:0055085//transmembrane transport;GO:0060707//trophoblast giant cell differentiation;GO:0060708//spongiotrophoblast differentiation;GO:0060713//labyrinthine layer morphogenesis;GO:1905867//epididymis development	--
ENSG00000189283	4.438	5.847	4.363	6.447	4.093	4.717	169	206	113	146	126	100	FHIT	fragile histidine triad diadenosine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3701]	Metabolism;Metabolism;Human Diseases;Human Diseases	Global and overview maps;Nucleotide metabolism;Cancer: specific types;Cancer: specific types	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko05222//Small cell lung cancer;ko05223//Non-small cell lung cancer	K01522;K01522;K01522;K01522	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043530//adenosine 5'-monophosphoramidase activity;GO:0047352//adenylylsulfate-ammonia adenylyltransferase activity;GO:0047627//adenylylsulfatase activity;GO:0047710//bis(5'-adenosyl)-triphosphatase activity	GO:0006163//purine nucleotide metabolic process;GO:0006915//apoptotic process;GO:0015964//diadenosine triphosphate catabolic process;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator	--
ENSG00000189292	0.476	0.64	0.11	1.08	1.588	1.385	10	14	2	14	20	22	ALKAL2	ALK and LTK ligand 2 [Source:HGNC Symbol;Acc:HGNC:27683]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0030298//receptor signaling protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding	GO:0010976//positive regulation of neuron projection development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070378//positive regulation of ERK5 cascade	--
ENSG00000189298	2.105	1.777	2.359	1.363	2.036	2.171	118	107.26	110.33	57	115	97	ZKSCAN3	zinc finger with KRAB and SCAN domains 3 [Source:HGNC Symbol;Acc:HGNC:13853]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006914//autophagy;GO:0007040//lysosome organization;GO:0010507//negative regulation of autophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000773//negative regulation of cellular senescence"	zf-C2H2
ENSG00000189299	0	0	0	0	0	0	0	0	0	0	0	0	FOXR2	forkhead box R2 [Source:HGNC Symbol;Acc:HGNC:30469]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Fork_head
ENSG00000189306	13.731	17.428	12.531	13.48	15.71	13.387	930	918.92	680	692	785	626.95	RRP7A	ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14545	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0032545//CURI complex;GO:0034456//UTP-C complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000028//ribosomal small subunit assembly;GO:0001825//blastocyst formation;GO:0006364//rRNA processing	--
ENSG00000189308	5.061	3.606	3.273	3.021	3.548	3.32	386	288	183	167	215	187	LIN54	lin-54 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:25397]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K21776	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0001067//transcription regulatory region nucleic acid binding;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0016584//nucleosome positioning"	--
ENSG00000189319	26.49	25.007	28.497	32.615	29.863	39.875	3151.38	2983.22	2483.93	2861.55	2987.54	3428.47	FAM53B	family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0006606//protein import into nucleus;GO:0016055//Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000189320	0.1	0.054	0.061	0.243	0.037	0.124	3	2	1	4	1	2	FAM180A	family with sequence similarity 180 member A [Source:HGNC Symbol;Acc:HGNC:33773]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000189325	0	0	0	0	0.031	0	0	0	0	0	2	0	BNIP5	BCL2 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:33769]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189326	0	0	0	0	0	0	0	0	0	0	0	0	SPANXN4	SPANX family member N4 [Source:HGNC Symbol;Acc:HGNC:33177]	-	-	-	-	-	-	-	--
ENSG00000189334	0	0	0	0	0.612	0.063	0	0	0	0	11	1	S100A14	S100 calcium binding protein A14 [Source:HGNC Symbol;Acc:HGNC:18901]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042379//chemokine receptor binding;GO:0048306//calcium-dependent protein binding	GO:0006915//apoptotic process;GO:0032496//response to lipopolysaccharide;GO:0034142//toll-like receptor 4 signaling pathway;GO:0042742//defense response to bacterium;GO:0055074//calcium ion homeostasis;GO:0071624//positive regulation of granulocyte chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000189337	17.242	14.782	15.836	18.298	19.215	19.983	1268	1168	872	1026	1162	1031	KAZN	"kazrin, periplakin interacting protein [Source:HGNC Symbol;Acc:HGNC:29173]"	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030057//desmosome	GO:0005515//protein binding	GO:0031424//keratinization	--
ENSG00000189339	24.879	24.666	24.063	24.464	25.68	28.112	3054	3051	2204	2229	2669	2483	SLC35E2B	solute carrier family 35 member E2B [Source:HGNC Symbol;Acc:HGNC:33941]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015297//antiporter activity	GO:0001835//blastocyst hatching;GO:0055085//transmembrane transport	--
ENSG00000189350	0.965	0.825	0.82	0.587	1.399	0.934	71	61	37	32	67	50	TOGARAM2	TOG array regulator of axonemal microtubules 2 [Source:HGNC Symbol;Acc:HGNC:33715]	-	-	-	-	GO:0005815//microtubule organizing center;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0043232//intracellular non-membrane-bounded organelle;GO:0072686//mitotic spindle	GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0051128//regulation of cellular component organization;GO:0090307//mitotic spindle assembly	--
ENSG00000189357	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31D4	SPATA31 subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:38601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000189362	2.23	2.363	2.281	1.701	2.109	1.498	113	112	74	85	90	77	NEMP2	nuclear envelope integral membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:33700]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000189367	0.028	0	0	0	0.006	0	2	0	0	0	0.92	0	KIAA0408	KIAA0408 [Source:HGNC Symbol;Acc:HGNC:21636]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189369	9.794	9.624	10.735	9.211	7.892	9.947	567	560	459	395	386	419	GSPT2	G1 to S phase transition 2 [Source:HGNC Symbol;Acc:HGNC:4622]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K03267	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0018444//translation release factor complex	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003747//translation release factor activity;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002184//cytoplasmic translational termination;GO:0006412//translation;GO:0007049//cell cycle"	--
ENSG00000189375	0	0	0	0	0.041	0	0	0	0	0	2	0	TBC1D28	TBC1 domain family member 28 [Source:HGNC Symbol;Acc:HGNC:26858]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000189376	7.121	6.012	5.895	6.892	6.679	6.416	193.5	164.21	118.31	138.71	153.32	126.84	C8orf76	chromosome 8 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:25924]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000189377	0	0	0	0	0.106	0	0	0	0	0	2	0	CXCL17	C-X-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:19232]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22627	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006935//chemotaxis;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010759//positive regulation of macrophage chemotaxis;GO:0030154//cell differentiation;GO:0048246//macrophage chemotaxis;GO:0050728//negative regulation of inflammatory response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090026//positive regulation of monocyte chemotaxis	--
ENSG00000189401	0	0	0	0	0	0	0	0	0	0	0	0	OTUD6A	OTU deubiquitinase 6A [Source:HGNC Symbol;Acc:HGNC:32312]	-	-	-	-	-	GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0035523//protein K29-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination;GO:1990167//protein K27-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination	--
ENSG00000189403	138.174	132.582	122.132	107.142	108.863	106.388	4317	4039	2754	2546	2808	2414	HMGB1	high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983]	Organismal Systems;Cellular Processes;Cellular Processes;Genetic Information Processing	Immune system;Cell growth and death;Transport and catabolism;Replication and repair	ko04613//Neutrophil extracellular trap formation;ko04217//Necroptosis;ko04140//Autophagy - animal;ko03410//Base excision repair	K10802;K10802;K10802;K10802	GO:0000793//condensed chromosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0017053//transcription repressor complex;GO:0034774//secretory granule lumen;GO:0035868//alphav-beta3 integrin-HMGB1 complex;GO:1904813//ficolin-1-rich granule lumen	"GO:0000400//four-way junction DNA binding;GO:0000405//bubble DNA binding;GO:0000976//transcription cis-regulatory region binding;GO:0001530//lipopolysaccharide binding;GO:0001786//phosphatidylserine binding;GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005125//cytokine activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008301//DNA binding, bending;GO:0016829//lyase activity;GO:0019958//C-X-C chemokine binding;GO:0042056//chemoattractant activity;GO:0050786//RAGE receptor binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070182//DNA polymerase binding;GO:0097100//supercoiled DNA binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001773//myeloid dendritic cell activation;GO:0002218//activation of innate immune response;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002407//dendritic cell chemotaxis;GO:0002437//inflammatory response to antigenic stimulus;GO:0002643//regulation of tolerance induction;GO:0002840//regulation of T cell mediated immune response to tumor cell;GO:0006265//DNA topological change;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006914//autophagy;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0010508//positive regulation of autophagy;GO:0017055//negative regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0031175//neuron projection development;GO:0031507//heterochromatin assembly;GO:0032072//regulation of restriction endodeoxyribonuclease activity;GO:0032392//DNA geometric change;GO:0032425//positive regulation of mismatch repair;GO:0032689//negative regulation of interferon-gamma production;GO:0032732//positive regulation of interleukin-1 production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033151//V(D)J recombination;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0035711//T-helper 1 cell activation;GO:0042104//positive regulation of activated T cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0043277//apoptotic cell clearance;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043371//negative regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0043410//positive regulation of MAPK cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045063//T-helper 1 cell differentiation;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0048584//positive regulation of response to stimulus;GO:0050918//positive chemotaxis;GO:0051106//positive regulation of DNA ligation;GO:0051276//chromosome organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0097350//neutrophil clearance;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:2000426//negative regulation of apoptotic cell clearance;GO:2001200//positive regulation of dendritic cell differentiation"	HMG
ENSG00000189409	2.649	3.213	2.096	1.043	1.767	1.129	69	81	39	20	39	22	MMP23B	matrix metallopeptidase 23B [Source:HGNC Symbol;Acc:HGNC:7171]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0000003//reproduction;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process	--
ENSG00000189410	0.379	0.44	0.282	0.211	0.4	0.411	11	19	16	12	26	23	SH2D5	SH2 domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28819]	-	-	-	-	GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	-	--
ENSG00000189420	0.753	0.652	0.551	0.508	0.66	0.621	100	87	54	50	74	60	ZFP92	ZFP92 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:12865]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000189430	0	0	0	0	0	0	0	0	0	0	0	0	NCR1	natural cytotoxicity triggering receptor 1 [Source:HGNC Symbol;Acc:HGNC:6731]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K06741	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016514//SWI/SNF complex	GO:0005515//protein binding	GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0030101//natural killer cell activation;GO:0042269//regulation of natural killer cell mediated cytotoxicity	--
ENSG00000189431	0	0.068	0	0.07	0.02	0	0	4	0	3	1	0	RASSF10	Ras association domain family member 10 [Source:HGNC Symbol;Acc:HGNC:33984]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0050769//positive regulation of neurogenesis;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000189433	0	0	0	0	0	0	0	0	0	0	0	0	GJB4	gap junction protein beta 4 [Source:HGNC Symbol;Acc:HGNC:4286]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005243//gap junction channel activity;GO:0005515//protein binding	GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007608//sensory perception of smell;GO:0042048//olfactory behavior;GO:0055085//transmembrane transport;GO:1990349//gap junction-mediated intercellular transport	--
ENSG00000196071	0.08	0.264	0.108	0	0	0.073	3	10	3	0	0	2	OR2L13	olfactory receptor family 2 subfamily L member 13 [Source:HGNC Symbol;Acc:HGNC:19578]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196072	7.813	6.965	6.694	6.914	5.791	5.838	329	336	241	250	231	207	BLOC1S2	biogenesis of lysosomal organelles complex 1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:20984]	-	-	-	-	GO:0000930//gamma-tubulin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0031083//BLOC-1 complex;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex;GO:1904115//axon cytoplasm	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043015//gamma-tubulin binding	"GO:0007020//microtubule nucleation;GO:0008089//anterograde axonal transport;GO:0008284//positive regulation of cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0016197//endosomal transport;GO:0031175//neuron projection development;GO:0032418//lysosome localization;GO:0032438//melanosome organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048490//anterograde synaptic vesicle transport;GO:0051036//regulation of endosome size;GO:0060155//platelet dense granule organization;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule;GO:0097345//mitochondrial outer membrane permeabilization"	--
ENSG00000196074	0.014	0.03	0	0	0.021	0	1	3	0	0	2	0	SYCP2	synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding	GO:0007049//cell cycle;GO:0007130//synaptonemal complex assembly;GO:0007140//male meiotic nuclear division;GO:0007143//female meiotic nuclear division;GO:0009566//fertilization;GO:0009887//animal organ morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0048808//male genitalia morphogenesis;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0140013//meiotic nuclear division	--
ENSG00000196081	0.582	0.295	0.556	0.147	0.316	0.361	33.8	17.21	23.82	6.33	15.49	15.23	ZNF724	zinc finger protein 724 [Source:HGNC Symbol;Acc:HGNC:32460]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196083	2.351	2.979	2.204	2.68	2.532	1.897	179	233	138	136	173	123	IL1RAP	interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Signaling molecules and interaction;Immune system;Sensory system	ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04659//Th17 cell differentiation;ko04750//Inflammatory mediator regulation of TRP channels	K04723;K04723;K04723;K04723	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	"GO:0002114//interleukin-33 receptor activity;GO:0003953//NAD+ nucleosidase activity;GO:0004908//interleukin-1 receptor activity;GO:0005149//interleukin-1 receptor binding;GO:0016787//hydrolase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0061809//NAD+ nucleotidase, cyclic ADP-ribose generating"	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032754//positive regulation of interleukin-5 production;GO:0032755//positive regulation of interleukin-6 production;GO:0038172//interleukin-33-mediated signaling pathway;GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051965//positive regulation of synapse assembly;GO:0065003//protein-containing complex assembly;GO:0099151//regulation of postsynaptic density assembly;GO:0099545//trans-synaptic signaling by trans-synaptic complex;GO:0099560//synaptic membrane adhesion;GO:1905606//regulation of presynapse assembly	--
ENSG00000196090	2.002	1.742	2.427	1.966	2.45	2.488	433	423	467	353	496	465	PTPRT	protein tyrosine phosphatase receptor type T [Source:HGNC Symbol;Acc:HGNC:9682]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0016791//phosphatase activity;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0045294//alpha-catenin binding;GO:0045295//gamma-catenin binding;GO:0045296//cadherin binding;GO:0051393//alpha-actinin binding;GO:0070097//delta-catenin binding;GO:0097677//STAT family protein binding	GO:0006470//protein dephosphorylation;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016311//dephosphorylation;GO:0030336//negative regulation of cell migration;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0071354//cellular response to interleukin-6;GO:1904893//negative regulation of receptor signaling pathway via STAT;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	--
ENSG00000196091	0.014	0.014	0	0.017	0.05	0	1	1	0	1	3	0	MYBPC1	myosin binding protein C1 [Source:HGNC Symbol;Acc:HGNC:7549]	-	-	-	-	GO:0005829//cytosol;GO:0030016//myofibril;GO:0032982//myosin filament	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0017022//myosin binding;GO:0031432//titin binding	GO:0006936//muscle contraction;GO:0007155//cell adhesion	--
ENSG00000196092	0	0	0	0	0.007	0	0	0	0	0	1	0	PAX5	paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K09383	GO:0000785//chromatin;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0006959//humoral immune response;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0007568//aging;GO:0009887//animal organ morphogenesis;GO:0021670//lateral ventricle development;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0030534//adult behavior;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048856//anatomical structure development;GO:0051573//negative regulation of histone H3-K9 methylation"	PAX
ENSG00000196098	0	0	0	0	0	0	0	0	0	0	0	0	OR5K4	olfactory receptor family 5 subfamily K member 4 [Source:HGNC Symbol;Acc:HGNC:31291]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196099	0	0	0	0	0	0	0	0	0	0	0	0	OR6M1	olfactory receptor family 6 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:14711]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196104	6.422	5.7	7.254	3.339	3.943	4.565	298	271	250	115	152	153	SPOCK3	"SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 [Source:HGNC Symbol;Acc:HGNC:13565]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0004857//enzyme inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:2000146//negative regulation of cell motility	--
ENSG00000196109	0	0	0	0	0	0	0	0	0	0	0	0	ZNF676	zinc finger protein 676 [Source:HGNC Symbol;Acc:HGNC:20429]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196110	1.192	1.16	1.514	1.196	1.232	0.733	119	112	104	82	102	65	ZNF699	zinc finger protein 699 [Source:HGNC Symbol;Acc:HGNC:24750]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196116	4.745	4.773	5.08	4.183	4.302	4.042	363	367	287	237	278	225	TDRD7	tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831]	-	-	-	-	GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0033391//chromatoid body;GO:0035770//ribonucleoprotein granule;GO:0043186//P granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding	GO:0002089//lens morphogenesis in camera-type eye;GO:0007283//spermatogenesis;GO:0010608//posttranscriptional regulation of gene expression;GO:0030154//cell differentiation;GO:0030719//P granule organization;GO:0034587//piRNA metabolic process;GO:0070306//lens fiber cell differentiation	--
ENSG00000196118	3.627	1.977	2.595	1.899	2.702	1.025	66.01	33.83	40.72	30.14	49.71	15.6	CFAP119	cilia and flagella associated protein 119 [Source:HGNC Symbol;Acc:HGNC:28078]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0097228//sperm principal piece	-	-	--
ENSG00000196119	0	0	0	0	0	0	0	0	0	0	0	0	OR8A1	olfactory receptor family 8 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8469]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196123	1.575	1.153	1.385	2.233	2.024	1.866	113	85	73	117	121	97	KIAA0895L	KIAA0895 like [Source:HGNC Symbol;Acc:HGNC:34408]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000196126	1.295	1.171	1.781	1.165	1.035	0.701	33	30	34	22	23	13	HLA-DRB1	"major histocompatibility complex, class II, DR beta 1 [Source:HGNC Symbol;Acc:HGNC:4948]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0001772//immunological synapse;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0030247//polysaccharide binding;GO:0032395//MHC class II receptor activity;GO:0042605//peptide antigen binding;GO:0042608//T cell receptor binding;GO:0042609//CD4 receptor binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0001934//positive regulation of protein phosphorylation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002437//inflammatory response to antigenic stimulus;GO:0002469//myeloid dendritic cell antigen processing and presentation;GO:0002491//antigen processing and presentation of endogenous peptide antigen via MHC class II;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002842//positive regulation of T cell mediated immune response to tumor cell;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0008544//epidermis development;GO:0016045//detection of bacterium;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030225//macrophage differentiation;GO:0032653//regulation of interleukin-10 production;GO:0032673//regulation of interleukin-4 production;GO:0032689//negative regulation of interferon-gamma production;GO:0032831//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0033674//positive regulation of kinase activity;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042088//T-helper 1 type immune response;GO:0042130//negative regulation of T cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043382//positive regulation of memory T cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0045622//regulation of T-helper cell differentiation;GO:0045657//positive regulation of monocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046598//positive regulation of viral entry into host cell;GO:0050852//T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051262//protein tetramerization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000516//positive regulation of CD4-positive, alpha-beta T cell activation"	--
ENSG00000196131	0	0	0	0	0	0	0	0	0	0	0	0	VN1R2	vomeronasal 1 receptor 2 [Source:HGNC Symbol;Acc:HGNC:19872]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0016503//pheromone receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0019236//response to pheromone	--
ENSG00000196132	0.199	0.219	0.11	0.152	0.245	0.361	15	17	8	13	21	19	MYT1	myelin transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:7622]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation"	zf-C2HC
ENSG00000196136	492.402	499.118	499.169	297.873	344.831	370.777	16110.63	16391.84	12041.51	7212.31	9529.12	8822.3	SERPINA3	serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031093//platelet alpha granule lumen;GO:0034774//secretory granule lumen;GO:0035578//azurophil granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003677//DNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019216//regulation of lipid metabolic process;GO:0030277//maintenance of gastrointestinal epithelium	--
ENSG00000196139	0.694	0.283	0.47	0.274	0.742	0.068	14	7	7	5	14	1	AKR1C3	aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386]	Metabolism;Human Diseases;Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Lipid metabolism;Endocrine system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00590//Arachidonic acid metabolism;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis;ko00790//Folate biosynthesis	K04119;K04119;K04119;K04119;K04119;K04119	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0001758//retinal dehydrogenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0032052//bile acid binding;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0036130//prostaglandin H2 endoperoxidase reductase activity;GO:0036131//prostaglandin D2 11-ketoreductase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0045550//geranylgeranyl reductase activity;GO:0045703//ketoreductase activity;GO:0047017//prostaglandin-F synthase activity;GO:0047020//15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0047023//androsterone dehydrogenase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047787//delta4-3-oxosteroid 5beta-reductase activity;GO:0052650//NADP-retinol dehydrogenase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007584//response to nutrient;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009267//cellular response to starvation;GO:0010942//positive regulation of cell death;GO:0016488//farnesol catabolic process;GO:0019371//cyclooxygenase pathway;GO:0030216//keratinocyte differentiation;GO:0034614//cellular response to reactive oxygen species;GO:0042448//progesterone metabolic process;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0043170//macromolecule metabolic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0061370//testosterone biosynthetic process;GO:0070293//renal absorption;GO:0071276//cellular response to cadmium ion;GO:0071277//cellular response to calcium ion;GO:0071379//cellular response to prostaglandin stimulus;GO:0071384//cellular response to corticosteroid stimulus;GO:0071395//cellular response to jasmonic acid stimulus;GO:0071799//cellular response to prostaglandin D stimulus;GO:1900053//negative regulation of retinoic acid biosynthetic process;GO:2000224//regulation of testosterone biosynthetic process;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000196141	44.145	46.484	46.989	52.748	50.32	58.099	1697	1768	1359	1541	1678	1638	SPATS2L	spermatogenesis associated serine rich 2 like [Source:HGNC Symbol;Acc:HGNC:24574]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//protein-containing complex	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000196150	3.949	3.496	2.658	4.576	2.079	3.505	264	250	165	136	167	145	ZNF250	zinc finger protein 250 [Source:HGNC Symbol;Acc:HGNC:13044]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196151	6.386	6.416	7.244	7.238	6.407	7.307	236	241	199	201	197	199	WDSUB1	"WD repeat, sterile alpha motif and U-box domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26697]"	-	-	-	-	-	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0016567//protein ubiquitination	--
ENSG00000196152	2.553	2.563	3.579	2.401	2.412	3.029	114	114	117	79	87	98	ZNF79	zinc finger protein 79 [Source:HGNC Symbol;Acc:HGNC:13153]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000196154	7.967	12.57	15.547	9.39	8.325	17.453	86	137	124	75	76	138	S100A4	S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0050786//RAGE receptor binding	GO:0001837//epithelial to mesenchymal transition;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000196155	0.52	1.27	0.939	1.09	0.524	1.494	49	46	45	34	41	35	PLEKHG4	pleckstrin homology and RhoGEF domain containing G4 [Source:HGNC Symbol;Acc:HGNC:24501]	-	-	-	-	GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000196156	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-3	keratin associated protein 4-3 [Source:HGNC Symbol;Acc:HGNC:18908]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0007568//aging;GO:0042633//hair cycle	--
ENSG00000196159	2.073	2.231	1.623	1.008	1.37	1.115	657	697	381	230	379	264	FAT4	FAT atypical cadherin 4 [Source:HGNC Symbol;Acc:HGNC:23109]	Environmental Information Processing	Signal transduction	ko04392//Hippo signaling pathway - multiple species	K16669	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0003007//heart morphogenesis;GO:0007009//plasma membrane organization;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007219//Notch signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis;GO:0035329//hippo signaling;GO:0043931//ossification involved in bone maturation;GO:0048565//digestive tract development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0072006//nephron development;GO:0072137//condensed mesenchymal cell proliferation;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0098609//cell-cell adhesion	--
ENSG00000196169	0	0.013	0.066	0	0	0	0	1	2	0	0	0	KIF19	kinesin family member 19 [Source:HGNC Symbol;Acc:HGNC:26735]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATP hydrolysis activity	GO:0007018//microtubule-based movement;GO:0060404//axonemal microtubule depolymerization;GO:0070462//plus-end specific microtubule depolymerization	--
ENSG00000196171	0	0	0	0	0	0	0	0	0	0	0	0	OR6K2	olfactory receptor family 6 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:15029]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196172	1.454	0.79	1.146	0.688	2.271	0.602	196	107	80	59.12	83.13	59	ZNF681	zinc finger protein 681 [Source:HGNC Symbol;Acc:HGNC:26457]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196177	7.145	5.077	5.112	4.652	5.739	6.644	821	614	458	418	584	549	ACADSB	acyl-CoA dehydrogenase short/branched chain [Source:HGNC Symbol;Acc:HGNC:91]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Lipid metabolism	"ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00071//Fatty acid degradation"	K09478;K09478;K09478;K09478	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003853//2-methylacyl-CoA dehydrogenase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016937//short-branched-chain-acyl-CoA dehydrogenase activity;GO:0042802//identical protein binding;GO:0047119//2-methyl-branched-chain-enoyl-CoA reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0102035//isobutyryl-CoA:FAD oxidoreductase activity"	GO:0006082//organic acid metabolic process;GO:0006550//isoleucine catabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process	--
ENSG00000196182	11.153	11.787	13.01	13.148	12.852	14.187	854	899	734	740	825	783	STK40	serine/threonine kinase 40 [Source:HGNC Symbol;Acc:HGNC:21373]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0003016//respiratory system process;GO:0005977//glycogen metabolic process;GO:0006468//protein phosphorylation;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0030324//lung development;GO:0035264//multicellular organism growth;GO:0043066//negative regulation of apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0048286//lung alveolus development;GO:0060425//lung morphogenesis	--
ENSG00000196184	0	0	0	0	0	0	0	0	0	0	0	0	OR10J1	olfactory receptor family 10 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:8175]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007338//single fertilization;GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196187	3.086	3.735	4.189	3.924	4.486	4.354	263	320	259	241	309	251	TMEM63A	transmembrane protein 63A [Source:HGNC Symbol;Acc:HGNC:29118]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite;GO:0035579//specific granule membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0003676//nucleic acid binding;GO:0005227//calcium activated cation channel activity;GO:0005515//protein binding;GO:0008381//mechanosensitive ion channel activity;GO:1990760//osmolarity-sensing cation channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000196188	0	0	0	0	0	0	0	0	0	0	0	0	CTSE	cathepsin E [Source:HGNC Symbol;Acc:HGNC:2530]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K01382	GO:0005768//endosome;GO:0043231//intracellular membrane-bounded organelle	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0006508//proteolysis;GO:0016540//protein autoprocessing;GO:0019538//protein metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II	--
ENSG00000196189	24.357	25.275	30.388	36.102	35.627	35.205	1207	1142	1083	1256	1458	1180	SEMA4A	semaphorin 4A [Source:HGNC Symbol;Acc:HGNC:10729]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06521	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030215//semaphorin receptor binding;GO:0045499//chemorepellent activity	GO:0001525//angiogenesis;GO:0001755//neural crest cell migration;GO:0002250//adaptive immune response;GO:0002292//T cell differentiation involved in immune response;GO:0002376//immune system process;GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0010594//regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0045063//T-helper 1 cell differentiation;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:1904891//positive regulation of excitatory synapse assembly;GO:1905704//positive regulation of inhibitory synapse assembly	--
ENSG00000196196	0.052	0	0.14	0.209	0.061	0.071	1	0	2	3	1	1	HRCT1	histidine rich carboxyl terminus 1 [Source:HGNC Symbol;Acc:HGNC:33872]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000196199	8.879	5.731	5.12	5.547	4.491	7.356	535	404	285	231	307	301	MPHOSPH8	M-phase phosphoprotein 8 [Source:HGNC Symbol;Acc:HGNC:29810]	-	-	-	-	GO:0000786//nucleosome;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0044030//regulation of DNA methylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090309//positive regulation of DNA methylation-dependent heterochromatin assembly"	--
ENSG00000196208	1.167	0.719	0.765	0.538	0.897	0.544	118	83	56	51	82	52	GREB1	growth regulating estrogen receptor binding 1 [Source:HGNC Symbol;Acc:HGNC:24885]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	-	-	--
ENSG00000196209	0	0	0	0	0.021	0	0	0	0	0	1	0	SIRPB2	signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000196214	5.355	4.641	5.662	5.495	4.823	3.586	337	261	204	188	185	164	ZNF766	zinc finger protein 766 [Source:HGNC Symbol;Acc:HGNC:28063]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000196218	0.399	0.56	0.26	0.54	0.432	0.295	31	45	16	30	35	23	RYR1	ryanodine receptor 1 [Source:HGNC Symbol;Acc:HGNC:10483]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems	Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Endocrine system;Neurodegenerative disease;Signal transduction;Environmental adaptation;Nervous system	ko05022//Pathways of neurodegeneration - multiple diseases;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04921//Oxytocin signaling pathway;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04713//Circadian entrainment;ko04730//Long-term depression	K04961;K04961;K04961;K04961;K04961;K04961;K04961;K04961	GO:0005737//cytoplasm;GO:0005790//smooth endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0014802//terminal cisterna;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030659//cytoplasmic vesicle membrane;GO:0031301//integral component of organelle membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0070062//extracellular exosome;GO:1990425//ryanodine receptor complex	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0015278//calcium-release channel activity;GO:0046872//metal ion binding;GO:0048763//calcium-induced calcium release activity	GO:0001666//response to hypoxia;GO:0003151//outflow tract morphogenesis;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006936//muscle contraction;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0031000//response to caffeine;GO:0043588//skin development;GO:0043931//ossification involved in bone maturation;GO:0048741//skeletal muscle fiber development;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071313//cellular response to caffeine	--
ENSG00000196220	2.874	2.586	2.926	3.042	3.217	3.097	532	481	400	417	503	417	SRGAP3	SLIT-ROBO Rho GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:19744]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07526	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000196224	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-3	keratin associated protein 5-3 [Source:HGNC Symbol;Acc:HGNC:23598]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000196227	3.365	3.14	2.99	3.545	3.355	3.179	355	333	233	277	299	244	FAM217B	family with sequence similarity 217 member B [Source:HGNC Symbol;Acc:HGNC:16170]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000196228	0	0	0	0	0	0	0	0	0	0	0	0	SULT1C3	sulfotransferase family 1C member 3 [Source:HGNC Symbol;Acc:HGNC:33543]	-	-	-	-	GO:0005737//cytoplasm	GO:0004027//alcohol sulfotransferase activity;GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047704//bile-salt sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding	GO:0006629//lipid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008203//cholesterol metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation	--
ENSG00000196230	523.348	563.714	578.108	669.38	615.372	580.775	27307	29567	22280	25870	27129	22047	TUBB	tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0032991//protein-containing complex;GO:0035578//azurophil granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0044297//cell body;GO:0045121//membrane raft;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0032794//GTPase activating protein binding;GO:0042288//MHC class I protein binding;GO:0044877//protein-containing complex binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0042267//natural killer cell mediated cytotoxicity;GO:0050807//regulation of synapse organization;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0071895//odontoblast differentiation	--
ENSG00000196233	3.788	2.82	3.109	2.588	2.775	3.214	776	561	523	437	524	463	LCOR	ligand dependent nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:29503]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0001222//transcription corepressor binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0042826//histone deacetylase binding;GO:1990226//histone methyltransferase binding;GO:1990381//ubiquitin-specific protease binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0071392//cellular response to estradiol stimulus	HTH
ENSG00000196235	42.947	39.4	41.397	45.26	46.805	49.05	2881	3035	2228	2396	2841	2374	SUPT5H	"SPT5 homolog, DSIF elongation factor subunit [Source:HGNC Symbol;Acc:HGNC:11469]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032044//DSIF complex	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016239//positive regulation of macroautophagy;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0032785//negative regulation of DNA-templated transcription, elongation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1900364//negative regulation of mRNA polyadenylation"	--
ENSG00000196236	1.21	1.825	1.373	1.709	1.401	1.92	139	195	132	112	138	138	XPNPEP3	X-prolyl aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:28052]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0003094//glomerular filtration;GO:0006508//proteolysis;GO:0016485//protein processing	--
ENSG00000196240	0	0	0	0	0	0	0	0	0	0	0	0	OR2T2	olfactory receptor family 2 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:14725]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196242	0	0	0	0	0	0	0	0	0	0	0	0	OR2C3	olfactory receptor family 2 subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:15005]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196247	2.123	1.679	1.017	1.113	1.286	1.541	215	134	79	76	115	85	ZNF107	zinc finger protein 107 [Source:HGNC Symbol;Acc:HGNC:12887]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196248	0	0	0	0	0	0	0	0	0	0	0	0	OR10S1	olfactory receptor family 10 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:14807]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196260	0	0	0	0	0	0	0	0	0	0	0	0	SFTA2	surfactant associated 2 [Source:HGNC Symbol;Acc:HGNC:18386]	-	-	-	-	GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0030133//transport vesicle;GO:0031410//cytoplasmic vesicle	-	-	--
ENSG00000196262	562.122	588.676	607.063	680.832	548.975	583.503	8334	8992	6509	7240	7186	6217	PPIA	peptidylprolyl isomerase A [Source:HGNC Symbol;Acc:HGNC:9253]	Cellular Processes	Cell growth and death	ko04217//Necroptosis	K03767	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0034774//secretory granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003723//RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity;GO:0046790//virion binding;GO:0051082//unfolded protein binding;GO:1904399//heparan sulfate binding	GO:0000413//protein peptidyl-prolyl isomerization;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006457//protein folding;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0019076//viral release from host cell;GO:0030168//platelet activation;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0032148//activation of protein kinase B activity;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0034389//lipid droplet organization;GO:0034599//cellular response to oxidative stress;GO:0035307//positive regulation of protein dephosphorylation;GO:0042118//endothelial cell activation;GO:0043410//positive regulation of MAPK cascade;GO:0045069//regulation of viral genome replication;GO:0045070//positive regulation of viral genome replication;GO:0050714//positive regulation of protein secretion;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060352//cell adhesion molecule production;GO:0061944//negative regulation of protein K48-linked ubiquitination;GO:0070527//platelet aggregation;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1903901//negative regulation of viral life cycle;GO:2001233//regulation of apoptotic signaling pathway	--
ENSG00000196263	0.623	0.533	0.569	0.53	0.483	0.434	81	67	53	51	53	41	ZNF471	zinc finger protein 471 [Source:HGNC Symbol;Acc:HGNC:23226]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196266	0	0.051	0	0.208	0.364	0.282	0	1	0	3	6	4	OR10J3	olfactory receptor family 10 subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:14992]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196267	4.142	3.037	4.326	2.346	2.311	2.165	167	123	88	79	87	58	ZNF836	zinc finger protein 836 [Source:HGNC Symbol;Acc:HGNC:34333]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196268	4.601	4.535	5.767	3.709	4.173	5.401	237	182	165	174	169	169	ZNF493	zinc finger protein 493 [Source:HGNC Symbol;Acc:HGNC:23708]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196275	2.079	1.287	1.19	1.787	0.836	0.667	85.24	96.75	49.86	61.03	52.84	36.29	GTF2IRD2	GTF2I repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30775]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	GO:0006357//regulation of transcription by RNA polymerase II	GTF2I
ENSG00000196277	0	0	0	0	0	0	0	0	0	0	0	0	GRM7	glutamate metabotropic receptor 7 [Source:HGNC Symbol;Acc:HGNC:4599]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse	K04609;K04609;K04609	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0032279//asymmetric synapse;GO:0043198//dendritic shaft;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane;GO:0048786//presynaptic active zone	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0001642//group III metabotropic glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005509//calcium ion binding;GO:0008066//glutamate receptor activity;GO:0010855//adenylate cyclase inhibitor activity;GO:0016595//glutamate binding;GO:0030165//PDZ domain binding;GO:0046983//protein dimerization activity;GO:0070905//serine binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007605//sensory perception of sound;GO:0014050//negative regulation of glutamate secretion;GO:0031279//regulation of cyclase activity;GO:0043086//negative regulation of catalytic activity;GO:0050896//response to stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0061564//axon development;GO:0070085//glycosylation"	--
ENSG00000196284	3.432	4.172	2.883	2.696	2.246	1.924	124	144	78	83	79	71	SUPT3H	"SPT3 homolog, SAGA and STAGA complex component [Source:HGNC Symbol;Acc:HGNC:11466]"	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K11313	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0033276//transcription factor TFTC complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006282//regulation of DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0016573//histone acetylation;GO:0016578//histone deubiquitination;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000196289	0	0	0	0	0	0	0	0	0	0	0	0	BECN2	beclin 2 [Source:HGNC Symbol;Acc:HGNC:38606]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Neurodegenerative disease;Signal transduction;Transport and catabolism;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04136//Autophagy - other;ko04215//Apoptosis - multiple species	K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334;K08334	"GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0034271//phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272//phosphatidylinositol 3-kinase complex, class III, type II"	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0000045//autophagosome assembly;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0008333//endosome to lysosome transport;GO:0042593//glucose homeostasis;GO:0045324//late endosome to vacuole transport;GO:1990172//G protein-coupled receptor catabolic process	--
ENSG00000196290	10.658	11.409	12.837	10.263	11.55	14.932	264	274	220	183	248	255	NIF3L1	NGG1 interacting factor 3 like 1 [Source:HGNC Symbol;Acc:HGNC:13390]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	"GO:0030182//neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription"	--
ENSG00000196296	0.092	0.061	0.167	0.125	0.081	0.102	6	4	8	6	5	2	ATP2A1	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Cardiovascular disease;Circulatory system;Neurodegenerative disease;Endocrine system;Digestive system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05017//Spinocerebellar ataxia;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853;K05853	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031095//platelet dense tubular network membrane;GO:0031673//H zone;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex;GO:0048471//perinuclear region of cytoplasm	GO:0000166//nucleotide binding;GO:0005215//transporter activity;GO:0005388//P-type calcium transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015662//P-type ion transporter activity;GO:0016887//ATP hydrolysis activity;GO:0030899//calcium-dependent ATPase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006942//regulation of striated muscle contraction;GO:0008637//apoptotic mitochondrial changes;GO:0031448//positive regulation of fast-twitch skeletal muscle fiber contraction;GO:0032470//positive regulation of endoplasmic reticulum calcium ion concentration;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0034220//ion transmembrane transport;GO:0034976//response to endoplasmic reticulum stress;GO:0045988//negative regulation of striated muscle contraction;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0051659//maintenance of mitochondrion location;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0090076//relaxation of skeletal muscle;GO:0106134//positive regulation of cardiac muscle cell contraction;GO:1901896//positive regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1902082//positive regulation of calcium ion import into sarcoplasmic reticulum;GO:1903779//regulation of cardiac conduction;GO:1990036//calcium ion import into sarcoplasmic reticulum	--
ENSG00000196305	27.827	26.384	23.355	21.309	20.667	24.43	2609	2486	1612	1472	1634	1662	IARS1	isoleucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:5330]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01870	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0070062//extracellular exosome	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004822//isoleucine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0051020//GTPase binding	GO:0001649//osteoblast differentiation;GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006428//isoleucyl-tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000196313	14.052	15.223	16.028	16.447	16.274	16.635	1772.25	1941.37	1494.89	1538.76	1742.89	1538.38	POM121	POM121 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:19702]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14316;K14316	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000196323	8.634	8.089	8.922	7.405	8.996	10.621	1513	1138	837	819	993	1000	ZBTB44	zinc finger and BTB domain containing 44 [Source:HGNC Symbol;Acc:HGNC:25001]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	ZBTB
ENSG00000196329	0	0	0	0	0.032	0	0	0	0	0	1	0	GIMAP5	"GTPase, IMAP family member 5 [Source:HGNC Symbol;Acc:HGNC:18005]"	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032585//multivesicular body membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding	-	--
ENSG00000196335	0.074	0.074	0.106	0.04	0.087	0.064	5	5	5	2	5	3	STK31	serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000196337	0.014	0.025	0.033	0.019	0	0	1	1	1	1	0	0	CGB7	chorionic gonadotropin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:16451]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation	--
ENSG00000196338	0.538	0.855	0.596	0.447	0.418	0.793	40	65	33	24	30	40	NLGN3	neuroligin 3 [Source:HGNC Symbol;Acc:HGNC:14289]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K07378	"GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0045202//synapse;GO:0060076//excitatory synapse;GO:0089717//spanning component of membrane;GO:0098793//presynapse;GO:0098983//symmetric, GABA-ergic, inhibitory synapse;GO:0098984//neuron to neuron synapse;GO:0098985//asymmetric, glutamatergic, excitatory synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099060//integral component of postsynaptic specialization membrane"	GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042043//neurexin family protein binding;GO:0050839//cell adhesion molecule binding;GO:0097110//scaffold protein binding	"GO:0002087//regulation of respiratory gaseous exchange by nervous system process;GO:0006898//receptor-mediated endocytosis;GO:0007155//cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0007612//learning;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0048488//synaptic vesicle endocytosis;GO:0048675//axon extension;GO:0050804//modulation of chemical synaptic transmission;GO:0050808//synapse organization;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060024//rhythmic synaptic transmission;GO:0060080//inhibitory postsynaptic potential;GO:0071625//vocalization behavior;GO:0097104//postsynaptic membrane assembly;GO:0097105//presynaptic membrane assembly;GO:0099054//presynapse assembly;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000969//positive regulation of AMPA receptor activity"	--
ENSG00000196341	0	0	0	0	0	0	0	0	0	0	0	0	OR8D1	olfactory receptor family 8 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:8481]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196344	0	0	0	0	0	0	0	0	0	0	0	0	ADH7	"alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide [Source:HGNC Symbol;Acc:HGNC:256]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004031//aldehyde oxidase activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0019841//retinol binding;GO:0035276//ethanol binding;GO:0046872//metal ion binding;GO:0048019//receptor antagonist activity;GO:0050153//omega-hydroxydecanoate dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0006068//ethanol catabolic process;GO:0006069//ethanol oxidation;GO:0006629//lipid metabolic process;GO:0009617//response to bacterium;GO:0010430//fatty acid omega-oxidation;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process;GO:0045471//response to ethanol;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000196345	3.782	4.003	3.832	3.542	3.942	4.305	229	245	172	163	209	170	ZKSCAN7	zinc finger with KRAB and SCAN domains 7 [Source:HGNC Symbol;Acc:HGNC:12955]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196350	0	0	0	0	0	0	0	0	0	0	0	0	ZNF729	zinc finger protein 729 [Source:HGNC Symbol;Acc:HGNC:32464]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196352	21.795	18.793	21.441	17.029	19.139	22.385	832	721	589	493	592	598	CD55	CD55 molecule (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665]	Organismal Systems;Human Diseases;Organismal Systems	Immune system;Cardiovascular disease;Immune system	ko04640//Hematopoietic cell lineage;ko05416//Viral myocarditis;ko04610//Complement and coagulation cascades	K04006;K04006;K04006	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0030667//secretory granule membrane;GO:0031225//anchored component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0008289//lipid binding	"GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0002726//positive regulation of T cell cytokine production;GO:0006958//complement activation, classical pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030449//regulation of complement activation;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0045730//respiratory burst;GO:0045916//negative regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0046718//viral entry into host cell;GO:1903659//regulation of complement-dependent cytotoxicity;GO:2000516//positive regulation of CD4-positive, alpha-beta T cell activation;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000196353	0.051	0.144	0	0.035	0	0	4	9	0	2	0	0	CPNE4	copine 4 [Source:HGNC Symbol;Acc:HGNC:2317]	-	-	-	-	GO:0005886//plasma membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0071277//cellular response to calcium ion	--
ENSG00000196357	1.926	1.13	1.59	1.737	1.376	1.326	65	43	41	48	44	36	ZNF565	zinc finger protein 565 [Source:HGNC Symbol;Acc:HGNC:26726]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196358	0.01	0.021	0	0	0	0.071	1	2	0	0	0	5	NTNG2	netrin G2 [Source:HGNC Symbol;Acc:HGNC:14288]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction	ko04360//Axon guidance;ko04514//Cell adhesion molecules	K16359;K16359	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0031225//anchored component of membrane;GO:0043256//laminin complex;GO:0046658//anchored component of plasma membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098978//glutamatergic synapse;GO:0099029//anchored component of presynaptic active zone membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0007409//axonogenesis;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0010975//regulation of neuron projection development;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050804//modulation of chemical synaptic transmission;GO:0070831//basement membrane assembly;GO:0098698//postsynaptic specialization assembly;GO:0099560//synaptic membrane adhesion;GO:0150011//regulation of neuron projection arborization;GO:1905606//regulation of presynapse assembly;GO:2001222//regulation of neuron migration	--
ENSG00000196361	0.081	0.051	0.203	0.165	0.2	0.168	8	5	11	12	13	12	ELAVL3	ELAV like RNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3314]	-	-	-	-	GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding	GO:0007399//nervous system development;GO:0030154//cell differentiation	--
ENSG00000196363	13.524	14.659	17.847	17.831	13.695	17.494	839	867	755	729	722	711	WDR5	WD repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:12757]	Human Diseases	Endocrine and metabolic disease	ko04934//Cushing syndrome	K14963	GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0044545//NSL complex;GO:0044665//MLL1/2 complex;GO:0044666//MLL3/4 complex;GO:0048188//Set1C/COMPASS complex;GO:0071339//MLL1 complex;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific)	"GO:0001501//skeletal system development;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0031063//regulation of histone deacetylation;GO:0031175//neuron projection development;GO:0043966//histone H3 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0045722//positive regulation of gluconeogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051568//histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation;GO:1900095//regulation of dosage compensation by inactivation of X chromosome"	--
ENSG00000196365	40.406	42.231	42.117	49.403	47.027	46.124	2466	2582	1881	2163	2417	2050	LONP1	"lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001018//mitochondrial promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003727//single-stranded RNA binding;GO:0004176//ATP-dependent peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0043565//sequence-specific DNA binding;GO:0051880//G-quadruplex DNA binding;GO:0070182//DNA polymerase binding	GO:0000002//mitochondrial genome maintenance;GO:0001666//response to hypoxia;GO:0006508//proteolysis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0007005//mitochondrion organization;GO:0030163//protein catabolic process;GO:0032042//mitochondrial DNA metabolic process;GO:0034599//cellular response to oxidative stress;GO:0051131//chaperone-mediated protein complex assembly;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0070407//oxidation-dependent protein catabolic process	--
ENSG00000196367	13.139	12.146	12.953	10.641	12.091	12.135	3367.08	3158	2424	2002	2621	2250	TRRAP	transformation/transcription domain associated protein [Source:HGNC Symbol;Acc:HGNC:12347]	Human Diseases	Infectious disease: viral	ko05166//Human T-cell leukemia virus 1 infection	K08874	GO:0000123//histone acetyltransferase complex;GO:0000124//SAGA complex;GO:0000786//nucleosome;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0033276//transcription factor TFTC complex;GO:0035267//NuA4 histone acetyltransferase complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity	"GO:0006281//DNA repair;GO:0006282//regulation of DNA repair;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016310//phosphorylation;GO:0016573//histone acetylation;GO:0016578//histone deubiquitination;GO:0018193//peptidyl-amino acid modification;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042981//regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000112//regulation of cellular macromolecule biosynthetic process;GO:2000779//regulation of double-strand break repair"	--
ENSG00000196368	3.726	3.728	2.926	3.28	3.715	3.5	184	185.06	106.72	120	155	125.78	NUDT11	nudix hydrolase 11 [Source:HGNC Symbol;Acc:HGNC:18011]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000298//endopolyphosphatase activity;GO:0005515//protein binding;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity	GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	--
ENSG00000196369	1.56	1.474	1.508	0.898	1.12	1.405	211.64	208.74	146.14	82.34	110.39	118.25	SRGAP2B	SLIT-ROBO Rho GTPase activating protein 2B [Source:HGNC Symbol;Acc:HGNC:35237]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07526	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007399//nervous system development;GO:0030336//negative regulation of cell migration	--
ENSG00000196371	1.049	1.186	0.961	0.85	1.003	1.087	130	147.73	88	78	105	98	FUT4	fucosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:4015]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series;ko00515//Mannose type O-glycan biosynthesis	K07632;K07632;K07632	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0071944//cell periphery	GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0017083//4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0009311//oligosaccharide metabolic process;GO:0009312//oligosaccharide biosynthetic process;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:0097022//lymphocyte migration into lymph node;GO:1902624//positive regulation of neutrophil migration;GO:1903037//regulation of leukocyte cell-cell adhesion;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000196372	21.149	22.396	27.26	21.116	23.877	24.413	1193	1270	1135	882	1138	1002	ASB13	ankyrin repeat and SOCS box containing 13 [Source:HGNC Symbol;Acc:HGNC:19765]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000196376	0.27	0.31	0.117	0.334	0.321	0.133	26	33	8	23	28	9	SLC35F1	solute carrier family 35 member F1 [Source:HGNC Symbol;Acc:HGNC:21483]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0055085//transmembrane transport	--
ENSG00000196378	1.934	1.674	2.266	1.665	2.604	2.338	76	81	55	47	68	59	ZNF34	zinc finger protein 34 [Source:HGNC Symbol;Acc:HGNC:13098]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196381	0.337	0.286	0.333	0.286	0.454	0.274	15	17	16	13	25	13	ZNF781	zinc finger protein 781 [Source:HGNC Symbol;Acc:HGNC:26745]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000196383	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000196387	6.931	6.107	6.571	5.141	7.201	6.475	313.42	282.85	176.15	155.43	242.04	190.46	ZNF140	zinc finger protein 140 [Source:HGNC Symbol;Acc:HGNC:12925]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196388	0.965	2.395	2.093	2.568	1.466	1.669	24	52	34	40	28	27	INCA1	"inhibitor of CDK, cyclin A1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:32224]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0004860//protein kinase inhibitor activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0008285//negative regulation of cell population proliferation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000196391	0.798	0.925	2.898	0.539	0.798	2.009	66	75	51	33	51	67.04	ZNF774	zinc finger protein 774 [Source:HGNC Symbol;Acc:HGNC:33108]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000196396	18.856	20.378	16.929	16.556	17.601	16.507	1511	1629	1010	996	1170	942	PTPN1	protein tyrosine phosphatase non-receptor type 1 [Source:HGNC Symbol;Acc:HGNC:9642]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes	Cancer: overview;Endocrine system;Endocrine and metabolic disease;Cellular community - eukaryotes	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04910//Insulin signaling pathway;ko04931//Insulin resistance;ko04520//Adherens junction	K05696;K05696;K05696;K05696	GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030061//mitochondrial crista;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0097443//sorting endosome;GO:0098554//cytoplasmic side of endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030971//receptor tyrosine kinase binding;GO:0045296//cadherin binding;GO:0046875//ephrin receptor binding;GO:0051721//protein phosphatase 2A binding	GO:0006470//protein dephosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0009968//negative regulation of signal transduction;GO:0016311//dephosphorylation;GO:0030100//regulation of endocytosis;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031532//actin cytoskeleton reorganization;GO:0033157//regulation of intracellular protein transport;GO:0034620//cellular response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:0043407//negative regulation of MAP kinase activity;GO:0043507//positive regulation of JUN kinase activity;GO:0046626//regulation of insulin receptor signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1902202//regulation of hepatocyte growth factor receptor signaling pathway;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1903896//positive regulation of IRE1-mediated unfolded protein response;GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity;GO:2000646//positive regulation of receptor catabolic process	--
ENSG00000196405	38.855	40.901	36.704	38.105	37.104	31.117	1700.91	1843.89	1189.95	1248.94	1398.94	972.98	EVL	Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K23487	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0017124//SH3 domain binding	GO:0007015//actin filament organization;GO:0007166//cell surface receptor signaling pathway;GO:0007399//nervous system development;GO:0008154//actin polymerization or depolymerization;GO:0009887//animal organ morphogenesis;GO:0010633//negative regulation of epithelial cell migration;GO:0030838//positive regulation of actin filament polymerization;GO:0045010//actin nucleation;GO:0051289//protein homotetramerization;GO:0051496//positive regulation of stress fiber assembly;GO:1900028//negative regulation of ruffle assembly	--
ENSG00000196406	0	0	0	0	0	0	0	0	0	0	0	0	SPANXD	SPANX family member D [Source:HGNC Symbol;Acc:HGNC:14332]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000196407	0	0	0	0	0	0	0	0	0	0	0	0	THEM5	thioesterase superfamily member 5 [Source:HGNC Symbol;Acc:HGNC:26755]	Metabolism	Lipid metabolism	ko00062//Fatty acid elongation	K22554	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016787//hydrolase activity;GO:0102991//myristoyl-CoA hydrolase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0035965//cardiolipin acyl-chain remodeling	--
ENSG00000196408	0.181	0.592	0.244	0.175	0.196	0.116	3	11.77	5.06	3.03	2	2	NOXO1	NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043020//NADPH oxidase complex	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0019899//enzyme binding;GO:0035091//phosphatidylinositol binding	GO:0006801//superoxide metabolic process;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0022617//extracellular matrix disassembly;GO:0042554//superoxide anion generation;GO:0050790//regulation of catalytic activity;GO:0060263//regulation of respiratory burst	--
ENSG00000196411	20.988	20.958	18.805	16.941	17.891	16.683	1895	1902	1254	1133	1362	1096	EPHB4	EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K05113	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0001525//angiogenesis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0003007//heart morphogenesis;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000196415	0	0	0	0.264	0.058	0.067	0	0	0	4	1	1	PRTN3	proteinase 3 [Source:HGNC Symbol;Acc:HGNC:9495]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035578//azurophil granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019899//enzyme binding	GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006909//phagocytosis;GO:0008284//positive regulation of cell population proliferation;GO:0019730//antimicrobial humoral response;GO:0030574//collagen catabolic process;GO:0043547//positive regulation of GTPase activity;GO:0045217//cell-cell junction maintenance;GO:0050765//negative regulation of phagocytosis;GO:0072672//neutrophil extravasation;GO:0097029//mature conventional dendritic cell differentiation	--
ENSG00000196417	2.776	1.017	2.009	0.881	1.126	0.908	160	93.55	69.47	63	84	65	ZNF765	zinc finger protein 765 [Source:HGNC Symbol;Acc:HGNC:25092]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196418	2.127	1.317	1.754	1.699	1.869	2.384	86	56	51	49	63	71	ZNF124	zinc finger protein 124 [Source:HGNC Symbol;Acc:HGNC:12907]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196419	102.371	108.066	106.823	105.421	100.851	98.16	4515	4786	3473	3441	3753	3151	XRCC6	X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055]	Genetic Information Processing	Replication and repair	ko03450//Non-homologous end-joining	K10884	"GO:0000781//chromosome, telomeric region;GO:0000783//nuclear telomere cap complex;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0034774//secretory granule lumen;GO:0043564//Ku70:Ku80 complex;GO:0070418//DNA-dependent protein kinase complex;GO:0070419//nonhomologous end joining complex;GO:1904813//ficolin-1-rich granule lumen"	"GO:0000166//nucleotide binding;GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016829//lyase activity;GO:0030332//cyclin binding;GO:0042162//telomeric DNA binding;GO:0044877//protein-containing complex binding;GO:0045027//DNA end binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0097110//scaffold protein binding"	"GO:0000723//telomere maintenance;GO:0000725//recombinational repair;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0006266//DNA ligation;GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process;GO:0032508//DNA duplex unwinding;GO:0045087//innate immune response;GO:0045621//positive regulation of lymphocyte differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048660//regulation of smooth muscle cell proliferation;GO:0071480//cellular response to gamma radiation;GO:0071481//cellular response to X-ray;GO:0097680//double-strand break repair via classical nonhomologous end joining"	--
ENSG00000196420	0	0	0	0	0	0	0	0	0	0	0	0	S100A5	S100 calcium binding protein A5 [Source:HGNC Symbol;Acc:HGNC:10495]	-	-	-	-	GO:0005634//nucleus;GO:0043025//neuronal cell body	GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000196421	0.171	0	0	0	0.102	0	5	0	0	0	2	0	C20orf204	chromosome 20 open reading frame 204 [Source:HGNC Symbol;Acc:HGNC:27655]	-	-	-	-	-	-	-	--
ENSG00000196422	9.302	9.244	8.885	10.695	11.865	11.976	902	895	640	777	961	840	PPP1R26	protein phosphatase 1 regulatory subunit 26 [Source:HGNC Symbol;Acc:HGNC:29089]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0010923//negative regulation of phosphatase activity	--
ENSG00000196427	0	0	0	0	0	0	0	0	0	0	0	0	NBPF4	NBPF member 4 [Source:HGNC Symbol;Acc:HGNC:26550]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000196428	4.959	4.548	4.328	3.499	4.685	4.174	477	379	308	264	373	321	TSC22D2	TSC22 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:29095]	-	-	-	-	-	-	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006970//response to osmotic stress	TSC22
ENSG00000196431	0.119	0.83	0.161	2.333	0.494	0.164	2	14	2	29	7	2	CRYBA4	crystallin beta A4 [Source:HGNC Symbol;Acc:HGNC:2396]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0043010//camera-type eye development	--
ENSG00000196433	0	0	0	0	0	0	0	0	0	0	0	0	ASMT	acetylserotonin O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:750]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism	K00543;K00543	GO:0005829//cytosol	GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008172//S-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0017096//acetylserotonin O-methyltransferase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0006412//translation;GO:0006629//lipid metabolic process;GO:0019438//aromatic compound biosynthetic process;GO:0030187//melatonin biosynthetic process;GO:0032259//methylation;GO:0046219//indolalkylamine biosynthetic process	--
ENSG00000196436	1.409	0.968	1.051	1.051	1.316	1.2	71	49.06	39.11	39.25	56.02	44.02	NPIPB15	nuclear pore complex interacting protein family member B15 [Source:HGNC Symbol;Acc:HGNC:34409]	-	-	-	-	GO:0005576//extracellular region;GO:0005654//nucleoplasm	-	-	--
ENSG00000196437	1.628	1.636	1.525	1.116	1.56	1.373	124	116	95	69	104	74	ZNF569	zinc finger protein 569 [Source:HGNC Symbol;Acc:HGNC:24737]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196440	1.198	1.314	1.166	1.065	1.413	1.25	176	200	133	121	175	134	ARMCX4	armadillo repeat containing X-linked 4 [Source:HGNC Symbol;Acc:HGNC:28615]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000196449	4.967	4.686	5.284	7.708	5.85	4.995	190.38	180.53	149.58	218.86	189.46	139.32	YRDC	yrdC N6-threonylcarbamoyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:28905]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane	GO:0000049//tRNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity;GO:0061710//L-threonylcarbamoyladenylate synthase	GO:0002949//tRNA threonylcarbamoyladenosine modification;GO:0006450//regulation of translational fidelity;GO:0051051//negative regulation of transport	--
ENSG00000196453	8.375	8.241	9.405	8.536	9.805	9.379	551	545	457	416	545	449	ZNF777	zinc finger protein 777 [Source:HGNC Symbol;Acc:HGNC:22213]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process;GO:0008285//negative regulation of cell population proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051291//protein heterooligomerization"	zf-C2H2
ENSG00000196455	8.157	7.162	7.34	6.449	6.496	7.16	816	749	564	497	571	542	PIK3R4	phosphoinositide-3-kinase regulatory subunit 4 [Source:HGNC Symbol;Acc:HGNC:8982]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Transport and catabolism;Neurodegenerative disease;Signal transduction;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05131//Shigellosis;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04371//Apelin signaling pathway;ko04136//Autophagy - other	K08333;K08333;K08333;K08333;K08333;K08333;K08333;K08333;K08333	"GO:0005768//endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0034271//phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272//phosphatidylinositol 3-kinase complex, class III, type II;GO:0035032//phosphatidylinositol 3-kinase complex, class III;GO:0043231//intracellular membrane-bounded organelle;GO:0071561//nucleus-vacuole junction"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006622//protein targeting to lysosome;GO:0006623//protein targeting to vacuole;GO:0010506//regulation of autophagy;GO:0016236//macroautophagy;GO:0016241//regulation of macroautophagy;GO:0016310//phosphorylation;GO:0030242//autophagy of peroxisome;GO:0032465//regulation of cytokinesis;GO:0032801//receptor catabolic process;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0042149//cellular response to glucose starvation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045022//early endosome to late endosome transport;GO:0045324//late endosome to vacuole transport;GO:0097352//autophagosome maturation	--
ENSG00000196456	6.138	8.268	9.422	8.371	7.315	12.35	215	274	229	261	263	308	ZNF775	zinc finger protein 775 [Source:HGNC Symbol;Acc:HGNC:28501]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000196458	2.753	1.926	1.983	1.58	1.717	1.847	378	266.02	203	162	193	183	ZNF605	zinc finger protein 605 [Source:HGNC Symbol;Acc:HGNC:28068]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196459	1.292	1.129	1.355	1.152	0.964	1.853	61	59	54	43	47	49	TRAPPC2	trafficking protein particle complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:23068]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0001501//skeletal system development;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0016192//vesicle-mediated transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000196460	0.025	0	0	0	0	0	1	0	0	0	0	0	RFX8	regulatory factor X8 [Source:HGNC Symbol;Acc:HGNC:37253]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	RFX
ENSG00000196465	77.049	77.738	77.929	76.72	71.525	73.122	1324	1346	995	974	1032	917	MYL6B	myosin light chain 6B [Source:HGNC Symbol;Acc:HGNC:29823]	Cellular Processes;Organismal Systems;Organismal Systems	Cellular community - eukaryotes;Endocrine system;Circulatory system	ko04530//Tight junction;ko04921//Oxytocin signaling pathway;ko04270//Vascular smooth muscle contraction	K12751;K12751;K12751	GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0016461//unconventional myosin complex;GO:0070062//extracellular exosome	GO:0003774//cytoskeletal motor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle	GO:0006936//muscle contraction;GO:0007519//skeletal muscle tissue development;GO:0030049//muscle filament sliding	--
ENSG00000196466	0.381	0.633	0.726	0.542	0.385	0.765	21	34.11	28.72	22	17.44	29.83	ZNF799	zinc finger protein 799 [Source:HGNC Symbol;Acc:HGNC:28071]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196468	0	0	0.078	0.078	0	0.08	0	0	2	2	0	2	FGF16	fibroblast growth factor 16 [Source:HGNC Symbol;Acc:HGNC:3672]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Cell motility;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko05226//Gastric cancer;ko05218//Melanoma	K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358;K04358	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009266//response to temperature stimulus;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor	--
ENSG00000196470	45.833	51.31	33.462	19.921	19.405	17.624	1786.35	1876.67	964.99	626.95	683.76	562.73	SIAH1	siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857]	Environmental Information Processing;Genetic Information Processing;Cellular Processes	"Signal transduction;Folding, sorting and degradation;Cell growth and death"	ko04310//Wnt signaling pathway;ko04120//Ubiquitin mediated proteolysis;ko04115//p53 signaling pathway	K04506;K04506;K04506	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0031624//ubiquitin conjugating enzyme binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0030163//protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051402//neuron apoptotic process;GO:0060070//canonical Wnt signaling pathway;GO:1990000//amyloid fibril formation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000196475	0	0	0	0	0	0	0	0	0	0	0	0	GK2	glycerol kinase 2 [Source:HGNC Symbol;Acc:HGNC:4291]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00561//Glycerolipid metabolism	K00864;K00864;K00864	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0097225//sperm midpiece;GO:0097226//sperm mitochondrial sheath	"GO:0000166//nucleotide binding;GO:0004370//glycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0006071//glycerol metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006641//triglyceride metabolic process;GO:0007283//spermatogenesis;GO:0016310//phosphorylation;GO:0019563//glycerol catabolic process;GO:0030317//flagellated sperm motility;GO:0046167//glycerol-3-phosphate biosynthetic process;GO:0120317//sperm mitochondrial sheath assembly	--
ENSG00000196476	5.053	4.972	6.339	4.29	4.262	4.735	161	159	150	99	116	109	C20orf96	chromosome 20 open reading frame 96 [Source:HGNC Symbol;Acc:HGNC:16227]	-	-	-	-	-	-	-	--
ENSG00000196482	0.816	0.639	0.539	0.625	0.552	0.611	88	65	43	51	42	48	ESRRG	estrogen related receptor gamma [Source:HGNC Symbol;Acc:HGNC:3474]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0034056//estrogen response element binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0050682//AF-2 domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0120162//positive regulation of cold-induced thermogenesis"	ESR-like
ENSG00000196497	20.285	41.191	24.585	30.716	48.668	32.962	1356.96	1525.98	1011.87	1059.21	1202	888	IPO4	importin 4 [Source:HGNC Symbol;Acc:HGNC:19426]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K20221	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0031267//small GTPase binding;GO:0061608//nuclear import signal receptor activity	GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000196498	93.643	94.889	105.38	111.212	117.077	109.07	8829	9739	7745	7671	9215	7863	NCOR2	nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]	Human Diseases;Environmental Information Processing	Infectious disease: viral;Signal transduction	ko05169//Epstein-Barr virus infection;ko04330//Notch signaling pathway	K06065;K06065	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005112//Notch binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding;GO:0035259//glucocorticoid receptor binding;GO:0042826//histone deacetylase binding;GO:0042974//retinoic acid receptor binding;GO:0044877//protein-containing complex binding;GO:0046965//retinoid X receptor binding;GO:0047485//protein N-terminus binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007595//lactation;GO:0010243//response to organonitrogen compound;GO:0010565//regulation of cellular ketone metabolic process;GO:0032355//response to estradiol;GO:0044849//estrous cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA"	MYB
ENSG00000196502	33.163	35.134	40.285	41.826	38.184	38.376	1053.69	1095.09	906.3	991.55	1032.14	890.85	SULT1A1	sulfotransferase family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:11453]	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K01014	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047894//flavonol 3-sulfotransferase activity;GO:0050294//steroid sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding	GO:0006068//ethanol catabolic process;GO:0006584//catecholamine metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0009308//amine metabolic process;GO:0009812//flavonoid metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000196503	4.238	3.855	3.859	3.331	3.308	4.21	128	116	86	73	83	93	ARL9	ADP ribosylation factor like GTPase 9 [Source:HGNC Symbol;Acc:HGNC:23592]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	-	--
ENSG00000196504	13.966	11.814	9.203	6.916	8.329	9.03	1140.9	968.78	559	394	592.78	570.85	PRPF40A	pre-mRNA processing factor 40 homolog A [Source:HGNC Symbol;Acc:HGNC:16463]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12821	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005685//U1 snRNP;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0016607//nuclear speck;GO:0071004//U2-type prespliceosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0008360//regulation of cell shape;GO:0008380//RNA splicing;GO:0016477//cell migration;GO:0032465//regulation of cytokinesis;GO:0045292//mRNA cis splicing, via spliceosome;GO:0051301//cell division"	--
ENSG00000196505	3.158	3.368	3.862	2.406	3.39	3.152	313	314	234	175	255	210	GDAP2	ganglioside induced differentiation associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18010]	-	-	-	-	GO:0005765//lysosomal membrane	GO:0005515//protein binding	GO:0032526//response to retinoic acid	--
ENSG00000196507	18.524	17.035	16.628	13.925	12.965	15.152	412	382	275	229	244	247	TCEAL3	transcription elongation factor A like 3 [Source:HGNC Symbol;Acc:HGNC:28247]	-	-	-	-	GO:0005634//nucleus	GO:0050699//WW domain binding	-	--
ENSG00000196510	15.355	16.737	16.913	15.295	12.666	18.727	730	796	584	529	581	658	ANAPC7	anaphase promoting complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:17380]	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03354;K03354;K03354;K03354;K03354	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding;GO:0019903//protein phosphatase binding	GO:0007049//cell cycle;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0051301//cell division;GO:0051445//regulation of meiotic cell cycle;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000196511	3.695	3.598	4.447	3.676	4.005	4.452	186	174	166	138	170	132	TPK1	thiamin pyrophosphokinase 1 [Source:HGNC Symbol;Acc:HGNC:17358]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00730//Thiamine metabolism	K00949;K00949	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004788//thiamine diphosphokinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0030975//thiamine binding;GO:0042802//identical protein binding	GO:0006725//cellular aromatic compound metabolic process;GO:0006772//thiamine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0009229//thiamine diphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0042723//thiamine-containing compound metabolic process;GO:0072527//pyrimidine-containing compound metabolic process	--
ENSG00000196517	7.266	5.848	7.626	4.388	4.131	8.852	408.2	370	303	168	228	371	SLC6A9	solute carrier family 6 member 9 [Source:HGNC Symbol;Acc:HGNC:11056]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K05038	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0031045//dense core granule;GO:0032279//asymmetric synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098688//parallel fiber to Purkinje cell synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0005283//amino acid:sodium symporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015375//glycine:sodium symporter activity	GO:0003333//amino acid transmembrane transport;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0015816//glycine transport;GO:0035725//sodium ion transmembrane transport;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0055085//transmembrane transport;GO:0070455//positive regulation of heme biosynthetic process;GO:0071702//organic substance transport;GO:0071705//nitrogen compound transport;GO:0150104//transport across blood-brain barrier;GO:1903804//glycine import across plasma membrane;GO:1903825//organic acid transmembrane transport;GO:1904782//negative regulation of NMDA glutamate receptor activity	--
ENSG00000196526	18.263	20.857	15.679	15.928	18.22	12.863	2810	3223	1794	1825	2357	1434	AFAP1	actin filament associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24017]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0017124//SH3 domain binding;GO:0042169//SH2 domain binding	GO:0009966//regulation of signal transduction;GO:0051493//regulation of cytoskeleton organization	--
ENSG00000196531	476.54	485.948	461.452	441.846	420.133	421.878	7515	7683	5361	5173	5596	4923	NACA	nascent polypeptide associated complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:7629]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K03626	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005854//nascent polypeptide-associated complex;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0051082//unfolded protein binding	GO:0003231//cardiac ventricle development;GO:0006412//translation;GO:0006612//protein targeting to membrane;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0015031//protein transport;GO:0042060//wound healing;GO:0043403//skeletal muscle tissue regeneration;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0048742//regulation of skeletal muscle fiber development;GO:0061384//heart trabecula morphogenesis;GO:1901227//negative regulation of transcription from RNA polymerase II promoter involved in heart development;GO:1901228//positive regulation of transcription from RNA polymerase II promoter involved in heart development;GO:1905551//negative regulation of protein localization to endoplasmic reticulum;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis	--
ENSG00000196535	18.287	17.268	19.766	20.246	21.007	23.322	2742	2709	2325	2374	2740	2567	MYO18A	myosin XVIIIA [Source:HGNC Symbol;Acc:HGNC:31104]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005856//cytoskeleton;GO:0009986//cell surface;GO:0016020//membrane;GO:0016459//myosin complex;GO:0042641//actomyosin	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0043531//ADP binding;GO:0051015//actin filament binding"	GO:0006259//DNA metabolic process;GO:0007030//Golgi organization;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0043030//regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0048194//Golgi vesicle budding;GO:0050714//positive regulation of protein secretion;GO:0090161//Golgi ribbon formation;GO:0090164//asymmetric Golgi ribbon formation;GO:1903028//positive regulation of opsonization	--
ENSG00000196539	0	0	0	0	0	0	0	0	0	0	0	0	OR2T3	olfactory receptor family 2 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:14727]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196542	0.016	0	0.038	0	0.38	0.038	1	0	1	0	10	1	SPTSSB	serine palmitoyltransferase small subunit B [Source:HGNC Symbol;Acc:HGNC:24045]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex	GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0007029//endoplasmic reticulum organization;GO:0030148//sphingolipid biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:1904220//regulation of serine C-palmitoyltransferase activity	--
ENSG00000196544	4.595	3.657	4.266	4.36	4.196	3.934	175	140	120	123	135	109	BORCS6	BLOC-1 related complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:25939]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0032418//lysosome localization;GO:0051036//regulation of endosome size;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule	--
ENSG00000196547	40.208	38.251	39.64	38.313	38.581	48.172	3556	3705	2893	2513	3088	3456	MAN2A2	mannosidase alpha class 2A member 2 [Source:HGNC Symbol;Acc:HGNC:6825]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K01231;K01231;K01231	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0004572//mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity;GO:0015923//mannosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding"	GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006517//protein deglycosylation;GO:0008152//metabolic process	--
ENSG00000196549	0.238	0.355	0.27	0.104	0.194	0.132	25	30	16	5	15	6	MME	membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154]	Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Neurodegenerative disease;Immune system;Digestive system;Endocrine system	ko05010//Alzheimer disease;ko04640//Hematopoietic cell lineage;ko04974//Protein digestion and absorption;ko04614//Renin-angiotensin system	K01389;K01389;K01389;K01389	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0043025//neuronal cell body;GO:0044306//neuron projection terminus;GO:0045121//membrane raft;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0001786//phosphatidylserine binding;GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0070012//oligopeptidase activity;GO:1901612//cardiolipin binding	GO:0001822//kidney development;GO:0001890//placenta development;GO:0006508//proteolysis;GO:0006518//peptide metabolic process;GO:0007568//aging;GO:0007611//learning or memory;GO:0016485//protein processing;GO:0019233//sensory perception of pain;GO:0030324//lung development;GO:0046449//creatinine metabolic process;GO:0050435//amyloid-beta metabolic process;GO:0050769//positive regulation of neurogenesis;GO:0061837//neuropeptide processing;GO:0071345//cellular response to cytokine stimulus;GO:0071492//cellular response to UV-A;GO:0071493//cellular response to UV-B;GO:0090399//replicative senescence;GO:0097242//amyloid-beta clearance;GO:0150094//amyloid-beta clearance by cellular catabolic process;GO:1900273//positive regulation of long-term synaptic potentiation	--
ENSG00000196550	0.615	0.483	0.208	0.281	0.265	0.196	12.83	11.23	2	5.9	4.83	4.64	FAM72A	family with sequence similarity 72 member A [Source:HGNC Symbol;Acc:HGNC:24044]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000196553	0	0	0	0	0	0	0	0	0	0	0	0	CCDC196	coiled-coil domain containing 196 [Source:HGNC Symbol;Acc:HGNC:20100]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000196557	2.218	2.479	3.01	4.189	4.011	4.503	344	363	319	464	526	493	CACNA1H	calcium voltage-gated channel subunit alpha1 H [Source:HGNC Symbol;Acc:HGNC:1395]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Endocrine and metabolic disease;Environmental adaptation;Endocrine system;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04934//Cushing syndrome;ko04713//Circadian entrainment;ko04925//Aldosterone synthesis and secretion;ko04929//GnRH secretion;ko04927//Cortisol synthesis and secretion	K04855;K04855;K04855;K04855;K04855;K04855;K04855	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008332//low voltage-gated calcium channel activity;GO:0046872//metal ion binding;GO:0097110//scaffold protein binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0007520//myoblast fusion;GO:0008016//regulation of heart contraction;GO:0019228//neuronal action potential;GO:0032342//aldosterone biosynthetic process;GO:0032870//cellular response to hormone stimulus;GO:0034220//ion transmembrane transport;GO:0034651//cortisol biosynthetic process;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0035865//cellular response to potassium ion;GO:0042391//regulation of membrane potential;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0098662//inorganic cation transmembrane transport;GO:2000344//positive regulation of acrosome reaction	--
ENSG00000196562	4.105	4.744	2.28	5.637	4.846	4.288	330	378	133	269	308	234	SULF2	sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005886//plasma membrane;GO:0009986//cell surface	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0001822//kidney development;GO:0002063//chondrocyte development;GO:0003094//glomerular filtration;GO:0009611//response to wounding;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0014846//esophagus smooth muscle contraction;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030201//heparan sulfate proteoglycan metabolic process;GO:0032836//glomerular basement membrane development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0048706//embryonic skeletal system development;GO:0051216//cartilage development;GO:0060348//bone development;GO:0060384//innervation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097421//liver regeneration;GO:2000345//regulation of hepatocyte proliferation	--
ENSG00000196565	0	0	0	0	0	0	0	0	0	0	0	0	HBG2	hemoglobin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4832]	-	-	-	-	GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex;GO:0072562//blood microparticle	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0031721//hemoglobin alpha binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000196569	15.337	10.69	12.762	11.219	11.284	12.792	2625	2081	1622	1599	1868	1865	LAMA2	laminin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6482]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Cardiovascular disease;Cardiovascular disease;Infectious disease: parasitic;Cancer: specific types;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637;K05637	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0016020//membrane;GO:0031594//neuromuscular junction;GO:0042383//sarcolemma;GO:0043083//synaptic cleft;GO:0062023//collagen-containing extracellular matrix;GO:0098637//protein complex involved in cell-matrix adhesion	GO:0005102//signaling receptor binding;GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent	"GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007517//muscle organ development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0032224//positive regulation of synaptic transmission, cholinergic;GO:0035633//maintenance of blood-brain barrier;GO:0045785//positive regulation of cell adhesion;GO:0045995//regulation of embryonic development;GO:0051149//positive regulation of muscle cell differentiation;GO:0110011//regulation of basement membrane organization;GO:2001046//positive regulation of integrin-mediated signaling pathway"	--
ENSG00000196570	0	0	0	0	0	0	0	0	0	0	0	0	PFN3	profilin 3 [Source:HGNC Symbol;Acc:HGNC:18627]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Signal transduction	ko05014//Amyotrophic lateral sclerosis;ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway	K05759;K05759;K05759;K05759;K05759	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003779//actin binding;GO:0008289//lipid binding	GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0032233//positive regulation of actin filament bundle assembly	--
ENSG00000196576	128.9	134.519	143.43	183.709	180.87	169.457	17103	17930	14037	17280	20242	16331	PLXNB2	plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06821	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity	GO:0001843//neural tube closure;GO:0001932//regulation of protein phosphorylation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007405//neuroblast proliferation;GO:0007420//brain development;GO:0008360//regulation of cell shape;GO:0010976//positive regulation of neuron projection development;GO:0030334//regulation of cell migration;GO:0043087//regulation of GTPase activity;GO:0045727//positive regulation of translation;GO:0050772//positive regulation of axonogenesis;GO:0071526//semaphorin-plexin signaling pathway;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:1904861//excitatory synapse assembly;GO:2001222//regulation of neuron migration	--
ENSG00000196578	0	0	0	0	0	0	0	0	0	0	0	0	OR5AC2	olfactory receptor family 5 subfamily AC member 2 [Source:HGNC Symbol;Acc:HGNC:15431]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196581	0.35	0.099	0.278	0.328	0.368	0.685	34	25	39	31	41	45	AJAP1	adherens junctions associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30801]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0044214//spanning component of plasma membrane;GO:0044291//cell-cell contact zone	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0044877//protein-containing complex binding	GO:0001953//negative regulation of cell-matrix adhesion;GO:0007155//cell adhesion;GO:0030860//regulation of polarized epithelial cell differentiation;GO:0061045//negative regulation of wound healing	--
ENSG00000196584	0.253	0.201	0.192	0.177	0.108	0.111	25	20	14	13	9	8	XRCC2	X-ray repair cross complementing 2 [Source:HGNC Symbol;Acc:HGNC:12829]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10879	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000400//four-way junction DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA"	GO:0000278//mitotic cell cycle;GO:0000724//double-strand break repair via homologous recombination;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007098//centrosome cycle;GO:0010165//response to X-ray;GO:0010332//response to gamma radiation;GO:0022008//neurogenesis;GO:0035264//multicellular organism growth;GO:0042148//strand invasion;GO:0043524//negative regulation of neuron apoptotic process;GO:0050769//positive regulation of neurogenesis;GO:0051321//meiotic cell cycle;GO:2000269//regulation of fibroblast apoptotic process	--
ENSG00000196586	8.36	6.512	5.499	3.436	5.065	5.382	948	707	450	310	462	414	MYO6	myosin VI [Source:HGNC Symbol;Acc:HGNC:7605]	Human Diseases;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection	K10358;K10358	"GO:0001726//ruffle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005905//clathrin-coated pit;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0016461//unconventional myosin complex;GO:0016591//RNA polymerase II, holoenzyme;GO:0030136//clathrin-coated vesicle;GO:0030139//endocytic vesicle;GO:0030175//filopodium;GO:0030665//clathrin-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031941//filamentous actin;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0045334//clathrin-coated endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity"	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0043531//ADP binding;GO:0051015//actin filament binding;GO:0060001//minus-end directed microfilament motor activity	"GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0007015//actin filament organization;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0030048//actin filament-based movement;GO:0030050//vesicle transport along actin filament;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0042472//inner ear morphogenesis;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051046//regulation of secretion"	--
ENSG00000196588	10.241	11.023	11.72	11.341	10.561	13.282	768	778	612	578	719	646	MRTFA	myocardin related transcription factor A [Source:HGNC Symbol;Acc:HGNC:14334]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0043522//leucine zipper domain binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0010735//positive regulation of transcription via serum response element binding;GO:0030036//actin cytoskeleton organization;GO:0043086//negative regulation of catalytic activity;GO:0044319//wound healing, spreading of cells;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051145//smooth muscle cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II"	--
ENSG00000196589	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L2B	methyl-CpG binding domain protein 3 like 2B [Source:HGNC Symbol;Acc:HGNC:53435]	-	-	-	-	-	-	-	--
ENSG00000196591	41.192	36.846	36.485	31.839	35.117	33.319	1966	1695	1198	1067	1284	1141	HDAC2	histone deacetylase 2 [Source:HGNC Symbol;Acc:HGNC:4853]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Cancer: overview;Immune system;Cancer: overview;Substance dependence;Cancer: overview;Cell growth and death;Endocrine system;Cancer: specific types;Substance dependence;Aging;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism;ko05206//MicroRNAs in cancer;ko04110//Cell cycle;ko04919//Thyroid hormone signaling pathway;ko05220//Chronic myeloid leukemia;ko05031//Amphetamine addiction;ko04213//Longevity regulating pathway - multiple species;ko04330//Notch signaling pathway	K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067;K06067	"GO:0000118//histone deacetylase complex;GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016580//Sin3 complex;GO:0016581//NuRD complex;GO:0032991//protein-containing complex;GO:0035098//ESC/E(Z) complex"	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019213//deacetylase activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031492//nucleosomal DNA binding;GO:0033558//protein deacetylase activity;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0051059//NF-kappaB binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990841//promoter-specific chromatin binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001975//response to amphetamine;GO:0003300//cardiac muscle hypertrophy;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009913//epidermal cell differentiation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010977//negative regulation of neuron projection development;GO:0016358//dendrite development;GO:0016575//histone deacetylation;GO:0030336//negative regulation of cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031000//response to caffeine;GO:0032496//response to lipopolysaccharide;GO:0032732//positive regulation of interleukin-1 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032922//circadian regulation of gene expression;GO:0032967//positive regulation of collagen biosynthetic process;GO:0034605//cellular response to heat;GO:0035094//response to nicotine;GO:0042220//response to cocaine;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042659//regulation of cell fate specification;GO:0042733//embryonic digit morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0045862//positive regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048149//behavioral response to ethanol;GO:0048511//rhythmic process;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0055093//response to hyperoxia;GO:0060789//hair follicle placode formation;GO:0061000//negative regulation of dendritic spine development;GO:0061029//eyelid development in camera-type eye;GO:0061198//fungiform papilla formation;GO:0070301//cellular response to hydrogen peroxide;GO:0070828//heterochromatin organization;GO:0070932//histone H3 deacetylation;GO:0070933//histone H4 deacetylation;GO:0071300//cellular response to retinoic acid;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902437//positive regulation of male mating behavior;GO:1902455//negative regulation of stem cell population maintenance;GO:1902459//positive regulation of stem cell population maintenance;GO:1903351//cellular response to dopamine;GO:2000273//positive regulation of signaling receptor activity;GO:2000736//regulation of stem cell differentiation;GO:2000757//negative regulation of peptidyl-lysine acetylation"	--
ENSG00000196597	1.198	1.246	0.66	0.442	0.916	1.015	95	84	32	27	39	43	ZNF782	zinc finger protein 782 [Source:HGNC Symbol;Acc:HGNC:33110]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196600	0	0	0	0	0.007	0	0	0	0	0	1	0	SLC22A25	solute carrier family 22 member 25 [Source:HGNC Symbol;Acc:HGNC:32935]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0015711//organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000196604	0.047	0.065	0.193	0.353	0.191	0.015	4.24	5.88	12.79	21.11	14.51	1	POTEF	POTE ankyrin domain family member F [Source:HGNC Symbol;Acc:HGNC:33905]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005515//protein binding	GO:0001895//retina homeostasis	--
ENSG00000196605	1.051	1.249	1.425	0.245	0.513	1.461	42.03	42.02	38.01	16.03	23.03	28.01	ZNF846	zinc finger protein 846 [Source:HGNC Symbol;Acc:HGNC:27260]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196611	0.416	0.122	0.861	0.297	0.434	0	17	5	26	9	15	0	MMP1	matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Cancer: overview;Infectious disease: viral;Cardiovascular disease;Immune disease;Endocrine system;Immune system;Endocrine system;Cancer: specific types	ko05200//Pathways in cancer;ko05171//Coronavirus disease - COVID-19;ko05417//Lipid and atherosclerosis;ko05323//Rheumatoid arthritis;ko04926//Relaxin signaling pathway;ko04657//IL-17 signaling pathway;ko03320//PPAR signaling pathway;ko05219//Bladder cancer	K01388;K01388;K01388;K01388;K01388;K01388;K01388;K01388	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0031334//positive regulation of protein-containing complex assembly;GO:0044267//cellular protein metabolic process;GO:0071492//cellular response to UV-A	--
ENSG00000196616	0	0	0	0.054	0.397	0	0	0	0	1	23	0	ADH1B	"alcohol dehydrogenase 1B (class I), beta polypeptide [Source:HGNC Symbol;Acc:HGNC:250]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004745//NAD-retinol dehydrogenase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding"	GO:0001523//retinoid metabolic process;GO:0006069//ethanol oxidation;GO:0006629//lipid metabolic process;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process	--
ENSG00000196620	0	0	0	0	0	0	0	0	0	0	0	0	UGT2B15	UDP glucuronosyltransferase family 2 member B15 [Source:HGNC Symbol;Acc:HGNC:12546]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000196628	6.546	6.002	2.614	2.427	5.434	4.099	523	430	174	177	245	222	TCF4	transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11634]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0070369//beta-catenin-TCF7L2 complex;GO:1990907//beta-catenin-TCF complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001093//TFIIB-class transcription factor binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0065004//protein-DNA complex assembly"	bHLH
ENSG00000196632	0.751	0.879	0.59	0.408	0.531	0.626	174	200	101	70	104	104	WNK3	WNK lysine deficient protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:14543]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005912//adherens junction;GO:0005923//bicellular tight junction	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019869//chloride channel inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006884//cell volume homeostasis;GO:0007231//osmosensory signaling pathway;GO:0010765//positive regulation of sodium ion transport;GO:0010766//negative regulation of sodium ion transport;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0035556//intracellular signal transduction;GO:0035633//maintenance of blood-brain barrier;GO:0043066//negative regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0050801//ion homeostasis;GO:0051928//positive regulation of calcium ion transport;GO:0072659//protein localization to plasma membrane;GO:0090279//regulation of calcium ion import;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903288//positive regulation of potassium ion import across plasma membrane;GO:1904062//regulation of cation transmembrane transport;GO:2000651//positive regulation of sodium ion transmembrane transporter activity	--
ENSG00000196636	10.918	8.365	11.002	8.658	9.111	10.723	215	165	160	126	152	153	SDHAF3	succinate dehydrogenase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:21752]	-	-	-	-	GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix	-	GO:0006105//succinate metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0034553//mitochondrial respiratory chain complex II assembly	--
ENSG00000196639	0.48	0.579	0.407	0.605	0.506	0.62	46	44	23	34	35	33	HRH1	histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels	K04149;K04149;K04149	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004969//histamine receptor activity;GO:0004993//G protein-coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity	"GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0008542//visual learning;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0043114//regulation of vascular permeability;GO:0045907//positive regulation of vasoconstriction;GO:0048016//inositol phosphate-mediated signaling;GO:0048167//regulation of synaptic plasticity;GO:0048245//eosinophil chemotaxis;GO:0071420//cellular response to histamine;GO:0098664//G protein-coupled serotonin receptor signaling pathway"	--
ENSG00000196642	26.374	24.981	28.36	28.757	26.316	32.198	1557	1448	1271	1264	1351	1364	RABL6	"RAB, member RAS oncogene family like 6 [Source:HGNC Symbol;Acc:HGNC:24703]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	-	--
ENSG00000196646	3.105	1.858	1.849	2.355	1.49	1.574	177	120	102	75	94	85	ZNF136	zinc finger protein 136 [Source:HGNC Symbol;Acc:HGNC:12920]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196652	5.364	5.045	4.994	3.493	4.419	3.43	478	464	324	251	361	219	ZKSCAN5	zinc finger with KRAB and SCAN domains 5 [Source:HGNC Symbol;Acc:HGNC:12867]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196653	0.87	0.848	1.035	0.929	0.76	0.63	57	57	50	45	42	30	ZNF502	zinc finger protein 502 [Source:HGNC Symbol;Acc:HGNC:23718]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0019076//viral release from host cell;GO:0044794//positive regulation by host of viral process"	zf-C2H2
ENSG00000196655	19.232	20.827	23.246	20.196	18.292	22.571	546	591	473	424	437	457.01	TRAPPC4	trafficking protein particle complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:19943]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030008//TRAPP complex;GO:0030054//cell junction;GO:0030425//dendrite;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0005515//protein binding	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0006914//autophagy;GO:0016192//vesicle-mediated transport;GO:0016358//dendrite development;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000196659	4.218	4.242	3.418	3.296	3.131	3.758	332.38	336.02	198.9	192.37	208.44	215.48	TTC30B	tetratricopeptide repeat domain 30B [Source:HGNC Symbol;Acc:HGNC:26425]	-	-	-	-	GO:0005879//axonemal microtubule;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection;GO:0097542//ciliary tip	GO:0005515//protein binding;GO:0120170//intraciliary transport particle B binding	GO:0030030//cell projection organization;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0060271//cilium assembly	--
ENSG00000196660	8.598	8.719	7.87	5.725	5.976	5.306	948	926	610	426	540	418	SLC30A10	solute carrier family 30 member 10 [Source:HGNC Symbol;Acc:HGNC:25355]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0005384//manganese ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006828//manganese ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010312//detoxification of zinc ion;GO:0043524//negative regulation of neuron apoptotic process;GO:0055085//transmembrane transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071421//manganese ion transmembrane transport;GO:0071577//zinc ion transmembrane transport;GO:0071579//regulation of zinc ion transport;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1904385//cellular response to angiotensin;GO:1905802//regulation of cellular response to manganese ion;GO:2000773//negative regulation of cellular senescence	--
ENSG00000196663	14.404	15.179	15.709	14.701	14.76	15.61	2100.24	2212.93	1658.08	1588.65	1884.74	1663.72	TECPR2	tectonin beta-propeller repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:19957]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006914//autophagy;GO:0032527//protein exit from endoplasmic reticulum	--
ENSG00000196664	0	0	0	0	0.011	0	0	0	0	0	1	0	TLR7	toll like receptor 7 [Source:HGNC Symbol;Acc:HGNC:15631]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Immune system	ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko05164//Influenza A;ko05162//Measles;ko04620//Toll-like receptor signaling pathway	K05404;K05404;K05404;K05404;K05404	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032009//early phagosome;GO:0036020//endolysosome membrane;GO:0043235//receptor complex;GO:0045335//phagocytic vesicle	GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0035197//siRNA binding;GO:0038187//pattern recognition receptor activity	GO:0000165//MAPK cascade;GO:0001932//regulation of protein phosphorylation;GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007252//I-kappaB phosphorylation;GO:0007254//JNK cascade;GO:0032722//positive regulation of chemokine production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0034154//toll-like receptor 7 signaling pathway;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050729//positive regulation of inflammatory response;GO:0051607//defense response to virus;GO:0071260//cellular response to mechanical stimulus;GO:0098586//cellular response to virus;GO:1901224//positive regulation of NIK/NF-kappaB signaling	--
ENSG00000196666	0.034	0.273	0.093	0	0	0	1	8	2	0	0	0	FAM180B	family with sequence similarity 180 member B [Source:HGNC Symbol;Acc:HGNC:34451]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000196670	5.9	5.45	4.644	5.044	4.964	5.682	385	341	228	190	240	213	ZFP62	ZFP62 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23241]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000196678	3.26	3.183	2.5	2.45	2.45	1.878	208.05	196.83	113.28	116.01	127.9	84.34	ERI2	ERI1 exoribonuclease family member 2 [Source:HGNC Symbol;Acc:HGNC:30541]	-	-	-	-	-	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000196683	131.397	132.938	138.622	168.533	108.977	135.543	1183	1203	922	1124	829	888	TOMM7	translocase of outer mitochondrial membrane 7 [Source:HGNC Symbol;Acc:HGNC:21648]	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K17771	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0031647//regulation of protein stability;GO:0045040//protein insertion into mitochondrial outer membrane;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000196684	0	0	0	0	0	0	0	0	0	0	0	0	HSH2D	hematopoietic SH2 domain containing [Source:HGNC Symbol;Acc:HGNC:24920]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000196689	0.695	1.022	0.755	0.592	0.783	0.662	60	79	41	34	56.26	37	TRPV1	transient receptor potential cation channel subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:12716]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Sensory system	ko04080//Neuroactive ligand-receptor interaction;ko04750//Inflammatory mediator regulation of TRP channels	K05222;K05222	GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031226//intrinsic component of plasma membrane;GO:0032591//dendritic spine membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0000166//nucleotide binding;GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008324//cation transmembrane transporter activity;GO:0015276//ligand-gated ion channel activity;GO:0015278//calcium-release channel activity;GO:0017081//chloride channel regulator activity;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051219//phosphoprotein binding;GO:0097603//temperature-gated ion channel activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001659//temperature homeostasis;GO:0001660//fever generation;GO:0001774//microglial cell activation;GO:0002024//diet induced thermogenesis;GO:0002790//peptide secretion;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0006629//lipid metabolic process;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007635//chemosensory behavior;GO:0009268//response to pH;GO:0009408//response to heat;GO:0010243//response to organonitrogen compound;GO:0010459//negative regulation of heart rate;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0014047//glutamate secretion;GO:0014832//urinary bladder smooth muscle contraction;GO:0019233//sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0034605//cellular response to heat;GO:0043065//positive regulation of apoptotic process;GO:0043434//response to peptide hormone;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048265//response to pain;GO:0048266//behavioral response to pain;GO:0050954//sensory perception of mechanical stimulus;GO:0050955//thermoception;GO:0050960//detection of temperature stimulus involved in thermoception;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050968//detection of chemical stimulus involved in sensory perception of pain;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0060079//excitatory postsynaptic potential;GO:0060083//smooth muscle contraction involved in micturition;GO:0060454//positive regulation of gastric acid secretion;GO:0070588//calcium ion transmembrane transport;GO:0071312//cellular response to alkaloid;GO:0071318//cellular response to ATP;GO:0071345//cellular response to cytokine stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0071363//cellular response to growth factor stimulus;GO:0071468//cellular response to acidic pH;GO:0071502//cellular response to temperature stimulus;GO:0090212//negative regulation of establishment of blood-brain barrier;GO:0098703//calcium ion import across plasma membrane;GO:1901594//response to capsazepine;GO:1990090//cellular response to nerve growth factor stimulus	--
ENSG00000196693	7.729	3.898	8.339	3.17	4.679	8.999	559	394	333	228	316.45	334.98	ZNF33B	zinc finger protein 33B [Source:HGNC Symbol;Acc:HGNC:13097]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196700	10.985	10.809	12.571	12.458	12.706	13.325	1363	1348	1152	1145	1332	1203	ZNF512B	zinc finger protein 512B [Source:HGNC Symbol;Acc:HGNC:29212]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II	zf-C2H2
ENSG00000196704	36.24	35.944	35.28	29.44	31.101	32.498	1103	1041	767	670	826	687	AMZ2	archaelysin family metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:28041]	-	-	-	-	GO:0005575//cellular_component	GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000196705	3.717	1.507	1.683	1.01	2.263	3.732	280.51	178	125	109	149	161	ZNF431	zinc finger protein 431 [Source:HGNC Symbol;Acc:HGNC:20809]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0043433//negative regulation of DNA-binding transcription factor activity"	zf-C2H2
ENSG00000196711	0	0	0	0	0	0	0	0	0	0	0	0	ALKAL1	ALK and LTK ligand 1 [Source:HGNC Symbol;Acc:HGNC:33775]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0030298//receptor signaling protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding	GO:0010976//positive regulation of neuron projection development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070378//positive regulation of ERK5 cascade	--
ENSG00000196712	12.946	10.655	10.216	10.811	10.698	10.734	2857	2183	1772	1370	1880	1635	NF1	neurofibromin 1 [Source:HGNC Symbol;Acc:HGNC:7765]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Drug resistance: antineoplastic	ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K08052;K08052;K08052	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0098793//presynapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008429//phosphatidylethanolamine binding;GO:0031210//phosphatidylcholine binding	"GO:0000165//MAPK cascade;GO:0001649//osteoblast differentiation;GO:0001656//metanephros development;GO:0001666//response to hypoxia;GO:0001889//liver development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001952//regulation of cell-matrix adhesion;GO:0001953//negative regulation of cell-matrix adhesion;GO:0006469//negative regulation of protein kinase activity;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0007406//negative regulation of neuroblast proliferation;GO:0007420//brain development;GO:0007422//peripheral nervous system development;GO:0007507//heart development;GO:0007519//skeletal muscle tissue development;GO:0008285//negative regulation of cell population proliferation;GO:0008542//visual learning;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010468//regulation of gene expression;GO:0014044//Schwann cell development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016525//negative regulation of angiogenesis;GO:0021510//spinal cord development;GO:0021764//amygdala development;GO:0021897//forebrain astrocyte development;GO:0021915//neural tube development;GO:0021987//cerebral cortex development;GO:0022011//myelination in peripheral nervous system;GO:0030036//actin cytoskeleton organization;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030325//adrenal gland development;GO:0030336//negative regulation of cell migration;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0034605//cellular response to heat;GO:0035021//negative regulation of Rac protein signal transduction;GO:0038026//reelin-mediated signaling pathway;GO:0042060//wound healing;GO:0042127//regulation of cell population proliferation;GO:0042308//negative regulation of protein import into nucleus;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0043408//regulation of MAPK cascade;GO:0043409//negative regulation of MAPK cascade;GO:0043473//pigmentation;GO:0043525//positive regulation of neuron apoptotic process;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0043547//positive regulation of GTPase activity;GO:0045124//regulation of bone resorption;GO:0045671//negative regulation of osteoclast differentiation;GO:0045685//regulation of glial cell differentiation;GO:0045762//positive regulation of adenylate cyclase activity;GO:0045765//regulation of angiogenesis;GO:0046580//negative regulation of Ras protein signal transduction;GO:0046929//negative regulation of neurotransmitter secretion;GO:0048147//negative regulation of fibroblast proliferation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048485//sympathetic nervous system development;GO:0048593//camera-type eye morphogenesis;GO:0048712//negative regulation of astrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0048745//smooth muscle tissue development;GO:0048820//hair follicle maturation;GO:0048844//artery morphogenesis;GO:0048853//forebrain morphogenesis;GO:0050890//cognition;GO:0061534//gamma-aminobutyric acid secretion, neurotransmission;GO:0061535//glutamate secretion, neurotransmission;GO:0098597//observational learning;GO:1900271//regulation of long-term synaptic potentiation;GO:1902531//regulation of intracellular signal transduction;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand"	--
ENSG00000196715	8.696	7.249	8.633	8.742	8.057	6.575	930	883	677	637	757	585	VKORC1L1	vitamin K epoxide reductase complex subunit 1 like 1 [Source:HGNC Symbol;Acc:HGNC:21492]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K05357;K05357	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016900//oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor;GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0048038//quinone binding"	GO:0017187//peptidyl-glutamic acid carboxylation;GO:0034599//cellular response to oxidative stress;GO:0042373//vitamin K metabolic process	--
ENSG00000196724	1.328	0.886	1.705	0.721	0.963	1.102	64	47	56	40	38	43	ZNF418	zinc finger protein 418 [Source:HGNC Symbol;Acc:HGNC:20647]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196730	5.15	4.966	5.138	5.017	5.77	6.517	624	612	463	453	596	577	DAPK1	death associated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:2674]	Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Transport and catabolism;Cancer: specific types	ko05200//Pathways in cancer;ko04140//Autophagy - animal;ko05219//Bladder cancer	K08803;K08803;K08803	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:1990722//DAPK1-calmodulin complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017075//syntaxin-1 binding;GO:0042802//identical protein binding;GO:0106310//protein serine kinase activity	GO:0002357//defense response to tumor cell;GO:0002834//regulation of response to tumor cell;GO:0006417//regulation of translation;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010506//regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0016310//phosphorylation;GO:0017148//negative regulation of translation;GO:0035556//intracellular signal transduction;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046777//protein autophosphorylation;GO:0071346//cellular response to interferon-gamma;GO:0071447//cellular response to hydroperoxide;GO:0097190//apoptotic signaling pathway;GO:1904094//positive regulation of autophagic cell death;GO:2000310//regulation of NMDA receptor activity	--
ENSG00000196734	0	0	0	0	0	0	0	0	0	0	0	0	LCE1B	late cornified envelope 1B [Source:HGNC Symbol;Acc:HGNC:16611]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000196735	0.123	0.095	0.4	0.094	0.509	0	4	4	8	1	11	0	HLA-DQA1	"major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity;GO:0042605//peptide antigen binding;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000196739	12.702	11.436	11.222	6.588	9.067	9.699	1949	1738	1250	747	1176	1070	COL27A1	collagen type XXVII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22986]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005583//fibrillar collagen trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046872//metal ion binding	GO:0003431//growth plate cartilage chondrocyte development;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization	--
ENSG00000196743	18.976	19.774	18.521	18.372	18.531	16.367	1409	1441	1004	1017	1170	890	GM2A	GM2 ganglioside activator [Source:HGNC Symbol;Acc:HGNC:4367]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12383	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004563//beta-N-acetylhexosaminidase activity;GO:0005319//lipid transporter activity;GO:0008047//enzyme activator activity;GO:0016787//hydrolase activity;GO:0030290//sphingolipid activator protein activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0006869//lipid transport;GO:0007611//learning or memory;GO:0009313//oligosaccharide catabolic process;GO:0019915//lipid storage;GO:0050790//regulation of catalytic activity;GO:0050877//nervous system process;GO:0050885//neuromuscular process controlling balance	--
ENSG00000196747	0	0	0.132	0.131	0	0.268	0	0	1	1	0	2	H2AC13	H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000196748	0	0	0	0	0	0	0	0	0	0	0	0	CLPSL2	colipase like 2 [Source:HGNC Symbol;Acc:HGNC:21250]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0007586//digestion;GO:0016042//lipid catabolic process;GO:0032094//response to food;GO:0050790//regulation of catalytic activity	--
ENSG00000196754	3.293	2.716	1.524	0.908	1.348	2.173	39	37	16	13	13	18	S100A2	S100 calcium binding protein A2 [Source:HGNC Symbol;Acc:HGNC:10492]	-	-	-	-	GO:0005575//cellular_component	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0043542//endothelial cell migration	--
ENSG00000196757	1.931	1.087	1.349	1.628	1.261	1.268	116	66	63	72	64	55	ZNF700	zinc finger protein 700 [Source:HGNC Symbol;Acc:HGNC:25292]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196767	0.013	0	0.017	0	0	0.035	1	0	1	0	0	2	POU3F4	POU class 3 homeobox 4 [Source:HGNC Symbol;Acc:HGNC:9217]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003680//minor groove of adenine-thymine-rich DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007420//brain development;GO:0007605//sensory perception of sound;GO:0021879//forebrain neuron differentiation;GO:0048839//inner ear development;GO:0090103//cochlea morphogenesis;GO:2001054//negative regulation of mesenchymal cell apoptotic process"	Pou
ENSG00000196772	0	0	0	0	0	0	0	0	0	0	0	0	OR14A16	olfactory receptor family 14 subfamily A member 16 [Source:HGNC Symbol;Acc:HGNC:15022]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196776	27.358	24.942	24.535	29.154	32.373	26.681	1344	1284	953	1062	1239	1026	CD47	CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682]	Environmental Information Processing	Signaling molecules and interaction	ko04512//ECM-receptor interaction	K06266	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0070053//thrombospondin receptor activity;GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0098632//cell-cell adhesion mediator activity	GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0016477//cell migration;GO:0022409//positive regulation of cell-cell adhesion;GO:0032649//regulation of interferon-gamma production;GO:0032653//regulation of interleukin-10 production;GO:0032655//regulation of interleukin-12 production;GO:0032675//regulation of interleukin-6 production;GO:0032680//regulation of tumor necrosis factor production;GO:0034113//heterotypic cell-cell adhesion;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0050729//positive regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050870//positive regulation of T cell activation;GO:0051496//positive regulation of stress fiber assembly;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071349//cellular response to interleukin-12;GO:0098609//cell-cell adhesion;GO:1904669//ATP export;GO:1905450//negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:2000439//positive regulation of monocyte extravasation	--
ENSG00000196778	0	0	0	0	0	0	0	0	0	0	0	0	OR52K1	olfactory receptor family 52 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:15222]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196781	9.607	9.293	9.755	8.677	8.451	11.37	503	494	390	324	418	426	TLE1	"TLE family member 1, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11837]"	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:1990907//beta-catenin-TCF complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0140297//DNA-binding transcription factor binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0009887//animal organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000811//negative regulation of anoikis"	--
ENSG00000196782	1.106	1.135	0.668	0.961	0.984	0.92	157	162	70	101	118	95	MAML3	mastermind like transcriptional coactivator 3 [Source:HGNC Symbol;Acc:HGNC:16272]	Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Immune system;Signal transduction	ko05165//Human papillomavirus infection;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06061;K06061;K06061	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000196787	0.293	0.389	0	0.396	0.232	0.403	3	4	0	3	2	3	H2AC11	H2A clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4737]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000196792	6.642	5.961	7.163	3.865	4.908	5.68	512	409	335	207	291	339	STRN3	striatin 3 [Source:HGNC Symbol;Acc:HGNC:15720]	Environmental Information Processing	Signal transduction	ko04013//MAPK signaling pathway - fly	K17608	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0090443//FAR/SIN/STRIPAK complex	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0031267//small GTPase binding;GO:0044877//protein-containing complex binding;GO:0051721//protein phosphatase 2A binding;GO:0070016//armadillo repeat domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0032355//response to estradiol;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000196793	1.965	1.436	1.527	1.657	1.652	1.785	81	62	47	51	57	53	ZNF239	zinc finger protein 239 [Source:HGNC Symbol;Acc:HGNC:13031]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000196800	0	0	0	0	0	0	0	0	0	0	0	0	SPINK14	serine peptidase inhibitor Kazal type 14 (putative) [Source:HGNC Symbol;Acc:HGNC:33825]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000196805	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2B	small proline rich protein 2B [Source:HGNC Symbol;Acc:HGNC:11262]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000196811	0	0	0	0	0	0	0	0	0	0	0	0	CHRNG	cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04818	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0110165//cellular anatomical entity	GO:0004888//transmembrane signaling receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005515//protein binding;GO:0015267//channel activity;GO:0015464//acetylcholine receptor activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0030594//neurotransmitter receptor activity	"GO:0006811//ion transport;GO:0006936//muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060079//excitatory postsynaptic potential"	--
ENSG00000196812	4.146	4.763	4.593	2.544	2.499	3.937	110	127	90	50	56	76	ZSCAN16	zinc finger and SCAN domain containing 16 [Source:HGNC Symbol;Acc:HGNC:20813]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000196814	5.991	6.615	6.954	7.847	9.213	8.069	597	661	511	580	641	585	MVB12B	multivesicular body subunit 12B [Source:HGNC Symbol;Acc:HGNC:23368]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12186	GO:0000813//ESCRT I complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0015031//protein transport;GO:0019075//virus maturation;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046755//viral budding	--
ENSG00000196821	58.28	55.331	61.036	60.529	57.12	62.535	4976	4911	3757	3954	4321	4076	ILRUN	inflammation and lipid regulator with UBA-like and NBR1-like domains [Source:HGNC Symbol;Acc:HGNC:21215]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0002376//immune system process;GO:0016236//macroautophagy;GO:0032480//negative regulation of type I interferon production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0043392//negative regulation of DNA binding;GO:0045087//innate immune response;GO:0050687//negative regulation of defense response to virus;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000196826	0	0.007	0	0	0	0	0	0.66	0	0	0	0	ZNF709	novel zinc finger protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000196832	0	0.013	0	0	0	0	0	1	0	0	0	0	OR11G2	olfactory receptor family 11 subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:15346]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196834	0.13	0.113	0.045	0.158	0.174	0.079	18	15.8	4.56	16.27	20.36	8	POTEI	POTE ankyrin domain family member I [Source:HGNC Symbol;Acc:HGNC:37093]	-	-	-	-	GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001895//retina homeostasis	--
ENSG00000196839	6.24	5.84	5.539	6.182	5.558	3.991	195	186	128	144.14	148.17	95.3	ADA	adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]	Metabolism;Metabolism;Human Diseases	Global and overview maps;Nucleotide metabolism;Immune disease	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko05340//Primary immunodeficiency	K01488;K01488;K01488	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0060205//cytoplasmic vesicle lumen	"GO:0004000//adenosine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0019239//deaminase activity;GO:0046872//metal ion binding;GO:0046936//2'-deoxyadenosine deaminase activity"	GO:0000255//allantoin metabolic process;GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0001829//trophectodermal cell differentiation;GO:0001889//liver development;GO:0001890//placenta development;GO:0002314//germinal center B cell differentiation;GO:0002636//positive regulation of germinal center formation;GO:0002686//negative regulation of leukocyte migration;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0006154//adenosine catabolic process;GO:0006157//deoxyadenosine catabolic process;GO:0006196//AMP catabolic process;GO:0007155//cell adhesion;GO:0009117//nucleotide metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0010035//response to inorganic substance;GO:0010460//positive regulation of heart rate;GO:0014074//response to purine-containing compound;GO:0030324//lung development;GO:0030890//positive regulation of B cell proliferation;GO:0032261//purine nucleotide salvage;GO:0032263//GMP salvage;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0042110//T cell activation;GO:0043066//negative regulation of apoptotic process;GO:0043101//purine-containing compound salvage;GO:0043103//hypoxanthine salvage;GO:0044209//AMP salvage;GO:0045580//regulation of T cell differentiation;GO:0045582//positive regulation of T cell differentiation;GO:0045987//positive regulation of smooth muscle contraction;GO:0046059//dAMP catabolic process;GO:0046061//dATP catabolic process;GO:0046085//adenosine metabolic process;GO:0046101//hypoxanthine biosynthetic process;GO:0046103//inosine biosynthetic process;GO:0046111//xanthine biosynthetic process;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0048286//lung alveolus development;GO:0048541//Peyer's patch development;GO:0048566//embryonic digestive tract development;GO:0050728//negative regulation of inflammatory response;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0060169//negative regulation of adenosine receptor signaling pathway;GO:0060407//negative regulation of penile erection;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0070256//negative regulation of mucus secretion;GO:0072521//purine-containing compound metabolic process;GO:0110148//biomineralization	--
ENSG00000196843	8.107	8.089	8.294	8.437	7.977	8.807	352	357	274	273	293	281	ARID5A	AT-rich interaction domain 5A [Source:HGNC Symbol;Acc:HGNC:17361]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0030331//estrogen receptor binding;GO:0035613//RNA stem-loop binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046965//retinoid X receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0050681//androgen receptor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0002062//chondrocyte differentiation;GO:0002376//immune system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0032729//positive regulation of interferon-gamma production;GO:0032740//positive regulation of interleukin-17 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035066//positive regulation of histone acetylation;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071222//cellular response to lipopolysaccharide;GO:0071391//cellular response to estrogen stimulus;GO:2000318//positive regulation of T-helper 17 type immune response;GO:2000556//positive regulation of T-helper 1 cell cytokine production"	ARID
ENSG00000196844	0	0	0	0	0	0	0	0	0	0	0	0	PATE2	prostate and testis expressed 2 [Source:HGNC Symbol;Acc:HGNC:32249]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25370	GO:0005576//extracellular region;GO:0005615//extracellular space	-	-	--
ENSG00000196850	4.402	3.976	4.444	4.496	4.114	4.869	455.94	414	339.96	345	360	367	PPTC7	protein phosphatase targeting COQ7 [Source:HGNC Symbol;Acc:HGNC:30695]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0010795//regulation of ubiquinone biosynthetic process;GO:0070262//peptidyl-serine dephosphorylation	--
ENSG00000196859	0	0	0	0	0	0	0	0	0	0	0	0	KRT39	keratin 39 [Source:HGNC Symbol;Acc:HGNC:32971]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000196860	0.159	0	0	0	0	0	2	0	0	0	0	0	TOMM20L	translocase of outer mitochondrial membrane 20 like [Source:HGNC Symbol;Acc:HGNC:33752]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0030943//mitochondrion targeting sequence binding	GO:0006605//protein targeting;GO:0006886//intracellular protein transport;GO:0016031//tRNA import into mitochondrion;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000196862	0.05	0.04	0.024	0.01	0.034	0	7.42	5.96	2.65	1.12	4.3	0	RGPD4	RANBP2 like and GRIP domain containing 4 [Source:HGNC Symbol;Acc:HGNC:32417]	-	-	-	-	GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006607//NLS-bearing protein import into nucleus;GO:0046907//intracellular transport;GO:0050790//regulation of catalytic activity	--
ENSG00000196865	3.673	2.392	2.711	2.226	2.411	2.86	842	551	459	378	467	477	NHLRC2	NHL repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:24731]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031093//platelet alpha granule lumen	GO:0005515//protein binding	-	--
ENSG00000196866	0.121	0.094	0	0	0.224	0.071	1.28	1	0	0	2	0.55	H2AC7	H2A clustered histone 7 [Source:HGNC Symbol;Acc:HGNC:4729]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000196867	2.322	2.055	1.902	1.717	1.958	1.914	190	173	116	104	136	114	ZFP28	ZFP28 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:17801]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196872	1.219	1.686	1.534	2.849	2.049	2.224	91	132	91	165	132	130	CRACDL	CRACD like [Source:HGNC Symbol;Acc:HGNC:33454]	-	-	-	-	-	-	-	--
ENSG00000196873	11.54	12.212	3.882	5.665	8.728	12.022	195.83	211.44	55.31	76.22	125.19	148.46	CBWD3	COBW domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18519]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000196876	0.322	0.488	0.361	0.373	0.499	0.555	64	66	34	42	62	42	SCN8A	sodium voltage-gated channel alpha subunit 8 [Source:HGNC Symbol;Acc:HGNC:10596]	-	-	-	-	GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0033268//node of Ranvier;GO:0042995//cell projection;GO:0043194//axon initial segment	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005248//voltage-gated sodium channel activity;GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007399//nervous system development;GO:0007422//peripheral nervous system development;GO:0019228//neuronal action potential;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042552//myelination;GO:0055085//transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0098655//cation transmembrane transport	--
ENSG00000196878	0.049	0.162	0.017	0.017	0.066	0.083	4	5	1	1	5	5	LAMB3	laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Infectious disease: parasitic;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko05145//Toxoplasmosis;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06244;K06244;K06244;K06244;K06244;K06244;K06244;K06244	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005610//laminin-5 complex;GO:0043256//laminin complex;GO:0062023//collagen-containing extracellular matrix	GO:0005198//structural molecule activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035987//endodermal cell differentiation;GO:0050873//brown fat cell differentiation;GO:0070831//basement membrane assembly	--
ENSG00000196890	0.32	0.282	0.34	1.444	0.672	1.46	21	24	21	15	19	14	H2BU1	H2B.U histone 1 [Source:HGNC Symbol;Acc:HGNC:20514]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000196900	0	0	0	0	0	0	0	0	0	0	0	0	TEX43	testis expressed 43 [Source:HGNC Symbol;Acc:HGNC:33767]	-	-	-	-	-	GO:0005515//protein binding	GO:0030317//flagellated sperm motility	--
ENSG00000196911	5.247	3.835	3.257	2.182	2.718	3.907	467.41	338.31	229.58	168.8	203.25	254.56	KPNA5	karyopherin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6398]	Human Diseases;Human Diseases;Genetic Information Processing	Cancer: overview;Infectious disease: viral;Translation	ko05207//Chemical carcinogenesis - receptor activation;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport	K15042;K15042;K15042	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042564//NLS-dependent protein nuclear import complex	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus;GO:0015031//protein transport;GO:0016032//viral process	--
ENSG00000196912	0.299	0.375	0.506	1.12	0.324	0.219	33.86	24.03	19.64	37.56	25.17	16.62	ANKRD36B	ankyrin repeat domain 36B [Source:HGNC Symbol;Acc:HGNC:29333]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000196914	28.759	24.331	23.201	18.731	21.618	22.331	5160	4369	3083	2549	3269	2909	ARHGEF12	Rho guanine nucleotide exchange factor 12 [Source:HGNC Symbol;Acc:HGNC:14193]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cell motility;Infectious disease: bacterial;Cancer: overview;Development and regeneration;Circulatory system;Immune system;Immune system	ko05200//Pathways in cancer;ko05130//Pathogenic Escherichia coli infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04360//Axon guidance;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04625//C-type lectin receptor signaling pathway	K07532;K07532;K07532;K07532;K07532;K07532;K07532;K07532;K07532;K07532;K07532	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0001664//G protein-coupled receptor binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000196917	0	0	0	0	0.012	0	0	0	0	0	1	0	HCAR1	hydroxycarboxylic acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:4532]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K08401	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050995//negative regulation of lipid catabolic process	--
ENSG00000196923	31.127	31.823	27.458	28.392	28.319	25.119	911	956	609	614	702	513	PDLIM7	PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958]	-	-	-	-	GO:0001725//stress fiber;GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005912//adherens junction;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding	GO:0001503//ossification;GO:0006898//receptor-mediated endocytosis;GO:0007507//heart development;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0061061//muscle structure development	--
ENSG00000196924	230.345	248.685	250.703	242.204	250.972	210.131	39095	41423	30848	30245	35450	25806	FLNA	filamin A [Source:HGNC Symbol;Acc:HGNC:3754]	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes	Signal transduction;Infectious disease: bacterial;Cancer: overview;Cellular community - eukaryotes	ko04010//MAPK signaling pathway;ko05132//Salmonella infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion	K04437;K04437;K04437;K04437	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030018//Z disc;GO:0030426//growth cone;GO:0031523//Myb complex;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0043232//intracellular non-membrane-bounded organelle;GO:0044295//axonal growth cone;GO:0070062//extracellular exosome;GO:1990779//glycoprotein Ib-IX-V complex	GO:0001664//G protein-coupled receptor binding;GO:0003723//RNA binding;GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0019900//kinase binding;GO:0031267//small GTPase binding;GO:0034988//Fc-gamma receptor I complex binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0051020//GTPase binding;GO:0140297//DNA-binding transcription factor binding	"GO:0001525//angiogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0001974//blood vessel remodeling;GO:0003007//heart morphogenesis;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007597//blood coagulation, intrinsic pathway;GO:0010572//positive regulation of platelet activation;GO:0010977//negative regulation of neuron projection development;GO:0016479//negative regulation of transcription by RNA polymerase I;GO:0030030//cell projection organization;GO:0030036//actin cytoskeleton organization;GO:0030334//regulation of cell migration;GO:0031532//actin cytoskeleton reorganization;GO:0032231//regulation of actin filament bundle assembly;GO:0034394//protein localization to cell surface;GO:0035855//megakaryocyte development;GO:0042177//negative regulation of protein catabolic process;GO:0042307//positive regulation of protein import into nucleus;GO:0043066//negative regulation of apoptotic process;GO:0043113//receptor clustering;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0044319//wound healing, spreading of cells;GO:0045022//early endosome to late endosome transport;GO:0045184//establishment of protein localization;GO:0045216//cell-cell junction organization;GO:0048680//positive regulation of axon regeneration;GO:0050808//synapse organization;GO:0050821//protein stabilization;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051220//cytoplasmic sequestering of protein;GO:0051764//actin crosslink formation;GO:0060271//cilium assembly;GO:0070527//platelet aggregation;GO:0071526//semaphorin-plexin signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0090042//tubulin deacetylation;GO:0090307//mitotic spindle assembly;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1905000//regulation of membrane repolarization during atrial cardiac muscle cell action potential;GO:1905031//regulation of membrane repolarization during cardiac muscle cell action potential;GO:2001046//positive regulation of integrin-mediated signaling pathway"	--
ENSG00000196932	0.135	0.117	0.185	0.344	0.157	0.214	12	10	12	26	14	13	TMEM26	transmembrane protein 26 [Source:HGNC Symbol;Acc:HGNC:28550]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000196935	3.482	3.08	3.293	2.329	2.974	2.758	684	629	496	355	479	413	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17382]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07526	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration;GO:0050790//regulation of catalytic activity	--
ENSG00000196937	32.778	30.033	29.598	25.534	29.999	26.954	1099	1023	693	667	834	676	FAM3C	FAM3 metabolism regulating signaling molecule C [Source:HGNC Symbol;Acc:HGNC:18664]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0031089//platelet dense granule lumen;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0008150//biological_process;GO:0045721//negative regulation of gluconeogenesis	--
ENSG00000196943	7.49	7.896	9.257	10.002	8.015	7.682	939.09	984.82	857.28	885.52	849.02	692.26	NOP9	NOP9 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:19826]	-	-	-	-	"GO:0005575//cellular_component;GO:0005730//nucleolus;GO:0030686//90S preribosome;GO:0030688//preribosome, small subunit precursor"	GO:0003723//RNA binding	"GO:0000056//ribosomal small subunit export from nucleus;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0008150//biological_process"	--
ENSG00000196944	0	0	0	0	0	0	0	0	0	0	0	0	OR2T4	olfactory receptor family 2 subfamily T member 4 [Source:HGNC Symbol;Acc:HGNC:15016]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000196946	0	0	0	0	0	0	0	0	0	0	0	0	ZNF705A	zinc finger protein 705A [Source:HGNC Symbol;Acc:HGNC:32281]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196950	7.524	6.163	5.5	4.001	4.393	4.974	770	671	440	321	402	392	SLC39A10	solute carrier family 39 member 10 [Source:HGNC Symbol;Acc:HGNC:20861]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14716;K14716	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0002903//negative regulation of B cell apoptotic process;GO:0006811//ion transport;GO:0006829//zinc ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0030890//positive regulation of B cell proliferation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0055085//transmembrane transport;GO:0071578//zinc ion import across plasma membrane;GO:1903615//positive regulation of protein tyrosine phosphatase activity	--
ENSG00000196954	5.417	7.279	4.775	6.246	4.654	5.502	142	178	90	117	100	101	CASP4	caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway	K04394;K04394;K04394;K04394;K04394	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0061702//inflammasome complex;GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097169//AIM2 inflammasome complex	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0050700//CARD domain binding;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0012501//programmed cell death;GO:0016540//protein autoprocessing;GO:0042981//regulation of apoptotic process;GO:0045087//innate immune response;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050830//defense response to Gram-positive bacterium;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070269//pyroptosis;GO:0097193//intrinsic apoptotic signaling pathway;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1904646//cellular response to amyloid-beta;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway	--
ENSG00000196961	37.161	38.041	37.477	40.611	39.008	35.444	2586.72	2661.71	1927	2093.45	2293.5	1794	AP2A1	adaptor related protein complex 2 subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:561]	Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems	Neurodegenerative disease;Transport and catabolism;Nervous system;Excretory system	ko05016//Huntington disease;ko04144//Endocytosis;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K11824;K11824;K11824;K11824	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030122//AP-2 adaptor complex;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030131//clathrin adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032433//filopodium tip;GO:0036020//endolysosome membrane;GO:0045334//clathrin-coated endocytic vesicle	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0035615//clathrin adaptor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0140312//cargo adaptor activity	GO:0006886//intracellular protein transport;GO:0006895//Golgi to endosome transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0072583//clathrin-dependent endocytosis;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:1900126//negative regulation of hyaluronan biosynthetic process	--
ENSG00000196967	6.289	5.885	6.213	6.053	6.153	6.851	271.43	200.38	179.13	130.33	163.76	152.71	ZNF585A	zinc finger protein 585A [Source:HGNC Symbol;Acc:HGNC:26305]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000196968	10.213	11.439	11.521	10.335	10.284	10.889	439	496	366	330	374	342	FUT11	fucosyltransferase 11 [Source:HGNC Symbol;Acc:HGNC:19233]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding;GO:0008417//fucosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0046920//alpha-(1->3)-fucosyltransferase activity	GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0036071//N-glycan fucosylation	--
ENSG00000196972	4.484	5.057	4.542	5.776	5.611	5.763	262	297	196	250	277	245	SMIM10L2B	small integral membrane protein 10 like 2B [Source:HGNC Symbol;Acc:HGNC:34500]	-	-	-	-	-	-	-	--
ENSG00000196975	23.572	23.522	21.852	21.995	22.154	21.188	1030	1030	710	685	788	676	ANXA4	annexin A4 [Source:HGNC Symbol;Acc:HGNC:542]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0004859//phospholipase inhibitor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding;GO:0051059//NF-kappaB binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007219//Notch signaling pathway;GO:0030855//epithelial cell differentiation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0043066//negative regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0050819//negative regulation of coagulation	--
ENSG00000196976	10.37	10.119	12.488	12.856	10.917	10.758	208	204	185	191	185	157	LAGE3	L antigen family member 3 [Source:HGNC Symbol;Acc:HGNC:26058]	-	-	-	-	GO:0000408//EKC/KEOPS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0005515//protein binding	GO:0008033//tRNA processing;GO:0008150//biological_process;GO:0070525//tRNA threonylcarbamoyladenosine metabolic process	--
ENSG00000196981	2.501	2.385	2.344	1.98	2.329	1.939	218.73	209.65	151.44	128.28	172.13	123.42	WDR5B	WD repeat domain 5B [Source:HGNC Symbol;Acc:HGNC:17826]	Human Diseases	Endocrine and metabolic disease	ko04934//Cushing syndrome	K14963	GO:0048188//Set1C/COMPASS complex	GO:0005515//protein binding;GO:0042393//histone binding	GO:0051568//histone H3-K4 methylation	--
ENSG00000196990	0	0	0	0	0	0	0	0	0	0	0	0	FAM163B	family with sequence similarity 163 member B [Source:HGNC Symbol;Acc:HGNC:33277]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000196993	0.588	0.238	0.12	0.118	0.38	0.415	24.86	10.1	3.74	3.69	13.55	13.3	NPIPB9	nuclear pore complex interacting protein family member B9 [Source:HGNC Symbol;Acc:HGNC:41987]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000196998	27.475	26	26.848	30.217	27.328	28.041	790	750.16	577	639	658	585.8	WDR45	WD repeat domain 45 [Source:HGNC Symbol;Acc:HGNC:28912]	-	-	-	-	GO:0000407//phagophore assembly site;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019898//extrinsic component of membrane;GO:0034045//phagophore assembly site membrane	"GO:0005515//protein binding;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:1901981//phosphatidylinositol phosphate binding"	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006914//autophagy;GO:0009267//cellular response to starvation;GO:0034497//protein localization to phagophore assembly site;GO:0044804//autophagy of nucleus;GO:2000786//positive regulation of autophagosome assembly	--
ENSG00000197006	176.247	171.916	173.431	152.041	143.036	164.76	6581	6145	4567	4115	4544	4370	METTL9	methyltransferase like 9 [Source:HGNC Symbol;Acc:HGNC:24586]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0106370//protein-L-histidine N-pros-methyltransferase activity	GO:0032259//methylation	--
ENSG00000197008	2.006	1.841	1.602	2.166	1.654	1.768	98	84	62	69	72	66	ZNF138	zinc finger protein 138 [Source:HGNC Symbol;Acc:HGNC:12922]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197013	2.671	1.945	1.814	1.971	1.741	2.293	254.49	194	133	137	146	155	ZNF429	zinc finger protein 429 [Source:HGNC Symbol;Acc:HGNC:20817]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197016	1.504	1.334	1.042	0.85	1.52	1.351	208	173	100	94	159	112	ZNF470	zinc finger protein 470 [Source:HGNC Symbol;Acc:HGNC:22220]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197019	3.077	3.36	3.759	3.498	3.56	4.261	133	146	120	112	130	134	SERTAD1	SERTA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17932]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell population proliferation;GO:0030308//negative regulation of cell growth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000197020	2.556	2.555	1.934	1.317	1.28	1.454	181	144	85	71.21	79.24	85	ZNF100	zinc finger protein 100 [Source:HGNC Symbol;Acc:HGNC:12880]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197021	11.368	10.278	12.484	9.373	11.676	9.643	317.76	280.33	255.73	195.44	275.21	196.48	EOLA2	endothelium and lymphocyte associated ASCH domain 2 [Source:HGNC Symbol;Acc:HGNC:17402]	-	-	-	-	-	-	-	--
ENSG00000197024	4.598	4.339	4.001	3.616	3.93	4.236	467	461	333	274	311	293	ZNF398	zinc finger protein 398 [Source:HGNC Symbol;Acc:HGNC:18373]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000197037	4.973	4.607	4.232	4.483	5.436	6.514	380	376	261	277	339	336	ZSCAN25	zinc finger and SCAN domain containing 25 [Source:HGNC Symbol;Acc:HGNC:21961]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197043	212.815	225.699	237.26	227.74	224.404	231.148	11611	12332	9456	9185	10396	9049	ANXA6	annexin A6 [Source:HGNC Symbol;Acc:HGNC:544]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008289//lipid binding;GO:0015276//ligand-gated ion channel activity;GO:0015485//cholesterol binding;GO:0035374//chondroitin sulfate binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0001755//neural crest cell migration;GO:0001778//plasma membrane repair;GO:0003418//growth plate cartilage chondrocyte differentiation;GO:0006816//calcium ion transport;GO:0006937//regulation of muscle contraction;GO:0034220//ion transmembrane transport;GO:0051179//localization;GO:0051283//negative regulation of sequestering of calcium ion;GO:0051560//mitochondrial calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0097190//apoptotic signaling pathway	--
ENSG00000197044	1.282	0.539	0.48	0.574	0.693	0.372	116	50	30	38	54	25	ZNF441	zinc finger protein 441 [Source:HGNC Symbol;Acc:HGNC:20875]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197045	26.499	19.643	22.388	17.77	17.324	17.762	2192	1669	1336	1039	1191	1035	GMFB	glia maturation factor beta [Source:HGNC Symbol;Acc:HGNC:4373]	-	-	-	-	-	GO:0003779//actin binding;GO:0004860//protein kinase inhibitor activity;GO:0008047//enzyme activator activity;GO:0008083//growth factor activity;GO:0071933//Arp2/3 complex binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity;GO:0071846//actin filament debranching	--
ENSG00000197046	0.033	0.114	0	0.073	0	0.022	2	7	0	2	0	1	SIGLEC15	sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	-	GO:0032956//regulation of actin cytoskeleton organization;GO:0045124//regulation of bone resorption;GO:2001204//regulation of osteoclast development	--
ENSG00000197050	3.919	2.728	2.729	2.45	3.236	2.95	243	207	151	137	168	162	ZNF420	zinc finger protein 420 [Source:HGNC Symbol;Acc:HGNC:20649]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197054	0.932	0.536	1.274	0.763	0.978	0.737	46.96	32	41	23.83	41	30.03	ZNF763	zinc finger protein 763 [Source:HGNC Symbol;Acc:HGNC:27614]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197056	2.468	1.614	1.851	1.397	1.701	2.144	213	140	118	90	124	136	ZMYM1	zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253]	-	-	-	-	GO:0005634//nucleus	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity	-	--
ENSG00000197057	0	0	0	0	0	0	0	0	0	0	0	0	DTHD1	death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000197061	0	0	0.161	0	0	0	0	0	1	0	0	0	H4C3	H4 clustered histone 3 [Source:HGNC Symbol;Acc:HGNC:4787]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000197062	10.323	10.326	9.515	6.424	7.623	7.924	404.93	390	295	231	288	256	ZSCAN26	zinc finger and SCAN domain containing 26 [Source:HGNC Symbol;Acc:HGNC:12978]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197063	6.125	5.766	6.036	6.224	6.044	7.319	643	601	468	484	536	559	MAFG	MAF bZIP transcription factor G [Source:HGNC Symbol;Acc:HGNC:6781]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression;GO:0030534//adult behavior;GO:0030641//regulation of cellular pH;GO:0042127//regulation of cell population proliferation;GO:0045604//regulation of epidermal cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000197070	8.313	8.128	10.032	9.973	7.889	11.577	239	238	211	216	197	236	ARRDC1	arrestin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28633]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity;GO:1990763//arrestin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006858//extracellular transport;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0045746//negative regulation of Notch signaling pathway;GO:0140112//extracellular vesicle biogenesis	--
ENSG00000197077	13.345	13.751	14.045	10.811	12.059	12.943	2124	2183	1605	1340	1638	1545	KIAA1671	KIAA1671 [Source:HGNC Symbol;Acc:HGNC:29345]	-	-	-	-	-	-	-	--
ENSG00000197079	0	0	0	0	0	0	0	0	0	0	0	0	KRT35	keratin 35 [Source:HGNC Symbol;Acc:HGNC:6453]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0070062//extracellular exosome	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0009653//anatomical structure morphogenesis;GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000197081	21.007	17.33	20.076	15.521	18.599	19.456	4222	4489	3347	2859	3545	3429	IGF2R	insulin like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:5467]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04144//Endocytosis;ko04142//Lysosome	K06564;K06564	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005641//nuclear envelope lumen;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030118//clathrin coat;GO:0030133//transport vesicle;GO:0030139//endocytic vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0001965//G-protein alpha-subunit binding;GO:0001972//retinoic acid binding;GO:0005010//insulin-like growth factor-activated receptor activity;GO:0005515//protein binding;GO:0005520//insulin-like growth factor binding;GO:0005537//mannose binding;GO:0019899//enzyme binding;GO:0031995//insulin-like growth factor II binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0051219//phosphoprotein binding;GO:1905394//retromer complex binding	GO:0001889//liver development;GO:0006898//receptor-mediated endocytosis;GO:0007041//lysosomal transport;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0009791//post-embryonic development;GO:0031100//animal organ regeneration;GO:0032526//response to retinoic acid;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0044794//positive regulation by host of viral process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:1904772//response to tetrachloromethane	--
ENSG00000197084	0	0	0	0	0	0	0	0	0	0	0	0	LCE1C	late cornified envelope 1C [Source:HGNC Symbol;Acc:HGNC:29464]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000197093	0.178	0.074	0.084	0.203	0.141	0.123	6	3	3	6	5	4	GAL3ST4	galactose-3-O-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:24145]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular exosome	GO:0001733//galactosylceramide sulfotransferase activity;GO:0003824//catalytic activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0050694//galactose 3-O-sulfotransferase activity;GO:0050698//proteoglycan sulfotransferase activity	GO:0006790//sulfur compound metabolic process;GO:0007267//cell-cell signaling;GO:0009100//glycoprotein metabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0009247//glycolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0030166//proteoglycan biosynthetic process	--
ENSG00000197102	48.394	47.448	46.466	34.238	40.608	35.916	14322	14127	10151	7518	10182	7745	DYNC1H1	dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]	Human Diseases;Cellular Processes;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Excretory system	ko05132//Salmonella infection;ko04145//Phagosome;ko04962//Vasopressin-regulated water reabsorption	K10413;K10413;K10413	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030175//filopodium;GO:0030286//dynein complex;GO:0035578//azurophil granule lumen;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007052//mitotic spindle organization;GO:0007097//nuclear migration;GO:0008090//retrograde axonal transport;GO:0031122//cytoplasmic microtubule organization;GO:0032388//positive regulation of intracellular transport;GO:0033962//P-body assembly;GO:0034063//stress granule assembly;GO:0051293//establishment of spindle localization;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0072382//minus-end-directed vesicle transport along microtubule;GO:0090235//regulation of metaphase plate congression;GO:0120162//positive regulation of cold-induced thermogenesis;GO:1905832//positive regulation of spindle assembly	--
ENSG00000197106	1.45	1.771	0.864	2.971	3.44	2.539	193	237	85	293	387	246	SLC6A17	solute carrier family 6 member 17 [Source:HGNC Symbol;Acc:HGNC:31399]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030285//integral component of synaptic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0005515//protein binding;GO:0015293//symporter activity	GO:0006836//neurotransmitter transport;GO:0007420//brain development;GO:0015804//neutral amino acid transport;GO:0015816//glycine transport;GO:0015820//leucine transport;GO:0015824//proline transport;GO:0032328//alanine transport;GO:0035725//sodium ion transmembrane transport;GO:0150104//transport across blood-brain barrier	--
ENSG00000197110	0	0	0	0	0	0	0	0	0	0	0	0	IFNL3	interferon lambda 3 [Source:HGNC Symbol;Acc:HGNC:18365]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K22669;K22669	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity	GO:0007259//receptor signaling pathway via JAK-STAT;GO:0038196//type III interferon signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus;GO:0098586//cellular response to virus	--
ENSG00000197111	329.725	316.714	313.739	339.031	312.129	334.662	10584.95	10311.84	7480.61	8127.22	8524.24	7951.11	PCBP2	poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648]	Cellular Processes	Cell growth and death	ko04216//Ferroptosis	K13162	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:1990829//C-rich single-stranded DNA binding	GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0016071//mRNA metabolic process;GO:0039694//viral RNA genome replication;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050687//negative regulation of defense response to virus;GO:0051252//regulation of RNA metabolic process;GO:0051607//defense response to virus;GO:0075522//IRES-dependent viral translational initiation	--
ENSG00000197114	10.855	10.935	12.574	13.778	12.33	11.663	397.5	427.88	337.85	363.62	364.25	330.24	ZGPAT	zinc finger CCCH-type and G-patch domain containing [Source:HGNC Symbol;Acc:HGNC:15948]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0045892//negative regulation of transcription, DNA-templated"	Others
ENSG00000197119	23.339	23.057	30.132	25.181	24.659	26.522	1364	1279	1115	1114	1181	918	SLC25A29	solute carrier family 25 member 29 [Source:HGNC Symbol;Acc:HGNC:20116]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K15109	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005289//high-affinity arginine transmembrane transporter activity;GO:0005292//high-affinity lysine transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity	GO:0006844//acyl carnitine transport;GO:0006865//amino acid transport;GO:0015822//ornithine transport;GO:0055085//transmembrane transport;GO:0089709//L-histidine transmembrane transport;GO:1903401//L-lysine transmembrane transport;GO:1903826//arginine transmembrane transport;GO:1990575//mitochondrial L-ornithine transmembrane transport	--
ENSG00000197121	4.001	2.692	3.594	2.802	3.066	3.297	746	494	445	389	500	456	PGAP1	post-GPI attachment to proteins inositol deacylase 1 [Source:HGNC Symbol;Acc:HGNC:25712]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05294;K05294	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0050185//phosphatidylinositol deacylase activity"	GO:0006505//GPI anchor metabolic process;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007605//sensory perception of sound;GO:0009880//embryonic pattern specification;GO:0009948//anterior/posterior axis specification;GO:0015031//protein transport;GO:0016255//attachment of GPI anchor to protein;GO:0021871//forebrain regionalization;GO:0060322//head development;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport	--
ENSG00000197122	14.181	14.466	13.953	11.364	12.936	13.635	1376	1408	996	815	1055	934	SRC	"SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]"	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases	Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Development and regeneration;Cellular community - eukaryotes;Infectious disease: viral;Endocrine system;Cardiovascular disease;Endocrine system;Endocrine system;Immune system;Endocrine system;Immune system;Drug resistance: antineoplastic;Sensory system;Endocrine system;Cellular community - eukaryotes;Nervous system;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Endocrine system;Transport and catabolism;Cellular community - eukaryotes;Infectious disease: bacterial;Signal transduction;Cancer: specific types	ko05168//Herpes simplex virus 1 infection;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04144//Endocytosis;ko05152//Tuberculosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko05161//Hepatitis B;ko04921//Oxytocin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04912//GnRH signaling pathway;ko04540//Gap junction;ko04727//GABAergic synapse;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway;ko05219//Bladder cancer	K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704;K05704	"GO:0002102//podosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032587//ruffle membrane;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0099091//postsynaptic specialization, intracellular component"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005080//protein kinase C binding;GO:0005102//signaling receptor binding;GO:0005158//insulin receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0020037//heme binding;GO:0030331//estrogen receptor binding;GO:0042169//SH2 domain binding;GO:0043274//phospholipase binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding;GO:0046875//ephrin receptor binding;GO:0050839//cell adhesion molecule binding;GO:0051117//ATPase binding;GO:0051219//phosphoprotein binding;GO:0070700//BMP receptor binding;GO:0070851//growth factor receptor binding;GO:0071253//connexin binding;GO:0097110//scaffold protein binding	"GO:0001545//primary ovarian follicle growth;GO:0001819//positive regulation of cytokine production;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007172//signal complex assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0008283//cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009615//response to virus;GO:0010447//response to acidic pH;GO:0010628//positive regulation of gene expression;GO:0010632//regulation of epithelial cell migration;GO:0010634//positive regulation of epithelial cell migration;GO:0010641//positive regulation of platelet-derived growth factor receptor signaling pathway;GO:0010907//positive regulation of glucose metabolic process;GO:0010954//positive regulation of protein processing;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016236//macroautophagy;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0022407//regulation of cell-cell adhesion;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0030900//forebrain development;GO:0031295//T cell costimulation;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031648//protein destabilization;GO:0031667//response to nutrient levels;GO:0031954//positive regulation of protein autophosphorylation;GO:0032148//activation of protein kinase B activity;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032869//cellular response to insulin stimulus;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0033625//positive regulation of integrin activation;GO:0034332//adherens junction organization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034614//cellular response to reactive oxygen species;GO:0035306//positive regulation of dephosphorylation;GO:0035556//intracellular signal transduction;GO:0035635//entry of bacterium into host cell;GO:0036035//osteoclast development;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0038128//ERBB2 signaling pathway;GO:0042476//odontogenesis;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043114//regulation of vascular permeability;GO:0043149//stress fiber assembly;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043393//regulation of protein binding;GO:0043406//positive regulation of MAP kinase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045056//transcytosis;GO:0045087//innate immune response;GO:0045124//regulation of bone resorption;GO:0045453//bone resorption;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045747//positive regulation of Notch signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046777//protein autophosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048041//focal adhesion assembly;GO:0048477//oogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050847//progesterone receptor signaling pathway;GO:0050900//leukocyte migration;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0051222//positive regulation of protein transport;GO:0051385//response to mineralocorticoid;GO:0051602//response to electrical stimulus;GO:0051895//negative regulation of focal adhesion assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0051902//negative regulation of mitochondrial depolarization;GO:0051974//negative regulation of telomerase activity;GO:0060065//uterus development;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060491//regulation of cell projection assembly;GO:0060576//intestinal epithelial cell development;GO:0070102//interleukin-6-mediated signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070542//response to fatty acid;GO:0070555//response to interleukin-1;GO:0071222//cellular response to lipopolysaccharide;GO:0071375//cellular response to peptide hormone stimulus;GO:0071393//cellular response to progesterone stimulus;GO:0071398//cellular response to fatty acid;GO:0071456//cellular response to hypoxia;GO:0071498//cellular response to fluid shear stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071803//positive regulation of podosome assembly;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0086098//angiotensin-activated signaling pathway involved in heart process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:1900182//positive regulation of protein localization to nucleus;GO:1902533//positive regulation of intracellular signal transduction;GO:1903997//positive regulation of non-membrane spanning protein tyrosine kinase activity;GO:2000386//positive regulation of ovarian follicle development;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:2000573//positive regulation of DNA biosynthetic process;GO:2000588//positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:2000641//regulation of early endosome to late endosome transport;GO:2000811//negative regulation of anoikis;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001286//regulation of caveolin-mediated endocytosis"	--
ENSG00000197123	0	0	0	0	0	0	0	0	0	0	0	0	ZNF679	zinc finger protein 679 [Source:HGNC Symbol;Acc:HGNC:28650]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197124	0	0.031	0	0	0	0	0	1	0	0	0	0	ZNF682	zinc finger protein 682 [Source:HGNC Symbol;Acc:HGNC:28857]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197125	0	0	0	0	0	0	0	0	0	0	0	0	OR8B8	olfactory receptor family 8 subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:8477]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197128	6.598	8.393	5.443	6.729	6.663	5.961	566	633	350	412	430	367	ZNF772	zinc finger protein 772 [Source:HGNC Symbol;Acc:HGNC:33106]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197134	0	0	0	0	0	0	0	0	0	0	0	0	ZNF257	zinc finger protein 257 [Source:HGNC Symbol;Acc:HGNC:13498]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197136	10.542	12.38	12.298	12.445	13.708	11.886	1553	1833	1338	1358	1706	1274	PCNX3	pecanex 3 [Source:HGNC Symbol;Acc:HGNC:18760]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000197140	0.247	0.421	0.306	0.112	0.209	0.057	12	12	11	4	5	2	ADAM32	ADAM metallopeptidase domain 32 [Source:HGNC Symbol;Acc:HGNC:15479]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008237//metallopeptidase activity	GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007339//binding of sperm to zona pellucida	--
ENSG00000197142	0.496	0.244	0.572	0.04	0.29	0.139	34	17	17	2	17	7	ACSL5	acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0047676//arachidonate-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008610//lipid biosynthetic process;GO:0010747//positive regulation of long-chain fatty acid import across plasma membrane;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:2001236//regulation of extrinsic apoptotic signaling pathway	--
ENSG00000197147	2.918	2.743	2.733	2.925	2.811	2.836	461	439	314	331	333	328	LRRC8B	leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034702//ion channel complex	GO:0005225//volume-sensitive anion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0015698//inorganic anion transport;GO:0098656//anion transmembrane transport	--
ENSG00000197150	10.888	12.615	11.285	13.5	14.517	11.942	656	798	550	607	731	507	ABCB8	ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05655	GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0062157//mitochondrial ATP-gated potassium channel complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0140359//ABC-type transporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0140141//mitochondrial potassium ion transmembrane transport	--
ENSG00000197153	0	0	0	0	0	0	0	0	0	0	0	0	H3C12	H3 clustered histone 12 [Source:HGNC Symbol;Acc:HGNC:4774]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000197157	85.186	86.54	86.298	91.303	85.283	81.572	6073	6221	4540	4826	5153	4234	SND1	staphylococcal nuclease and tudor domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30646]	Human Diseases	Cancer: overview	ko05203//Viral carcinogenesis	K15979	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016442//RISC complex;GO:0042470//melanosome;GO:0070062//extracellular exosome;GO:0097433//dense body	GO:0003676//nucleic acid binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0045296//cadherin binding;GO:1905172//RISC complex binding	"GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006402//mRNA catabolic process;GO:0010564//regulation of cell cycle process;GO:0010587//miRNA catabolic process;GO:0031047//gene silencing by RNA;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000197162	3.863	5.673	4.868	5.303	4.704	4.91	245	357	225	247	251	225	ZNF785	zinc finger protein 785 [Source:HGNC Symbol;Acc:HGNC:26496]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197165	0.177	0.435	0.389	0.085	0.221	0.61	7.29	14	11.86	2	7.71	11.45	SULT1A2	sulfotransferase family 1A member 2 [Source:HGNC Symbol;Acc:HGNC:11454]	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K01014	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0047894//flavonol 3-sulfotransferase activity	GO:0006068//ethanol catabolic process;GO:0006584//catecholamine metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0009309//amine biosynthetic process;GO:0018958//phenol-containing compound metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000197168	0.521	0.166	0.456	0.185	0.304	0.289	53	18	26	17	32	26	NEK5	NIMA related kinase 5 [Source:HGNC Symbol;Acc:HGNC:7748]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051155//positive regulation of striated muscle cell differentiation;GO:2001056//positive regulation of cysteine-type endopeptidase activity	--
ENSG00000197170	11.969	10.605	9.503	8.471	8.899	9.822	657	555	400	338	388	387	PSMD12	"proteasome 26S subunit, non-ATPase 12 [Source:HGNC Symbol;Acc:HGNC:9557]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05169//Epstein-Barr virus infection;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K03035;K03035;K03035;K03035;K03035;K03035;K03035;K03035;K03035	"GO:0000502//proteasome complex;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0031595//nuclear proteasome complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen"	GO:0005515//protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000197172	0.029	0	0	0	0	0	1	0	0	0	0	0	MAGEA6	MAGE family member A6 [Source:HGNC Symbol;Acc:HGNC:6804]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010507//negative regulation of autophagy	--
ENSG00000197177	0.028	0	0	0	0.033	0	2	0	0	0	2	0	ADGRA1	adhesion G protein-coupled receptor A1 [Source:HGNC Symbol;Acc:HGNC:13838]	-	-	-	-	GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000197181	0.038	0.019	0.026	0.092	0.06	0.046	4	2	2	6	4	2	PIWIL2	piwi like RNA-mediated gene silencing 2 [Source:HGNC Symbol;Acc:HGNC:17644]	Organismal Systems	Development and regeneration	ko04320//Dorso-ventral axis formation	K02156	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010370//perinucleolar chromocenter;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0071546//pi-body;GO:0097433//dense body;GO:1990923//PET complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0034584//piRNA binding;GO:0046872//metal ion binding;GO:0061980//regulatory RNA binding;GO:1905538//polysome binding	"GO:0000966//RNA 5'-end processing;GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0030718//germ-line stem cell population maintenance;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process;GO:0042754//negative regulation of circadian rhythm;GO:0043046//DNA methylation involved in gamete generation;GO:0045727//positive regulation of translation;GO:0048477//oogenesis;GO:0048511//rhythmic process;GO:0051321//meiotic cell cycle;GO:0060903//positive regulation of meiosis I;GO:0071442//positive regulation of histone H3-K14 acetylation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1990511//piRNA biosynthetic process;GO:2000617//positive regulation of histone H3-K9 acetylation"	--
ENSG00000197183	14.506	15.706	12.749	14.732	14.759	16.278	1362	1312	976	985	1140	1117	NOL4L	nucleolar protein 4 like [Source:HGNC Symbol;Acc:HGNC:16106]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000197191	0.61	0.76	0.856	0.402	0.958	0.511	15	18	17	8	14	10	CYSRT1	cysteine rich tail 1 [Source:HGNC Symbol;Acc:HGNC:30529]	-	-	-	-	GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000197208	0.108	0.215	0.175	0.524	0.179	0.208	5	10	6	18	7	7	SLC22A4	solute carrier family 22 member 4 [Source:HGNC Symbol;Acc:HGNC:10968]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K08202	GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015226//carnitine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015491//cation:cation antiporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0030165//PDZ domain binding	GO:0006641//triglyceride metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007589//body fluid secretion;GO:0009437//carnitine metabolic process;GO:0015695//organic cation transport;GO:0015697//quaternary ammonium group transport;GO:0015879//carnitine transport;GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0089718//amino acid import across plasma membrane;GO:0098655//cation transmembrane transport;GO:1902603//carnitine transmembrane transport	--
ENSG00000197213	0	0.133	0	0	0.063	0.073	0	5	0	0	2	2	ZSCAN5B	zinc finger and SCAN domain containing 5B [Source:HGNC Symbol;Acc:HGNC:34246]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000197217	17.26	16.054	15.967	16.966	18.703	17.769	1564	1490	1085	1188	1392	1254	ENTPD4	ectonucleoside triphosphate diphosphohydrolase 4 [Source:HGNC Symbol;Acc:HGNC:14573]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K12305;K12305;K12305;K12305	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0031410//cytoplasmic vesicle;GO:0097637//integral component of autophagosome membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0004382//guanosine-diphosphatase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0036384//cytidine-diphosphatase activity;GO:0043273//CTPase activity;GO:0045134//uridine-diphosphatase activity	GO:0006256//UDP catabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0046036//CTP metabolic process;GO:0046712//GDP catabolic process	--
ENSG00000197223	11.412	8.927	12.028	9.973	9.216	12.169	285	269	221	193	190	221	C1D	C1D nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:29911]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12592	GO:0000176//nuclear exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex	GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016922//nuclear receptor binding	"GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing;GO:0006915//apoptotic process;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000197226	41.493	42.921	46.076	45.664	46.487	43.028	4437	4552	3639	3617	4200	3348	TBC1D9B	TBC1 domain family member 9B [Source:HGNC Symbol;Acc:HGNC:29097]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005096//GTPase activator activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0090630//activation of GTPase activity	--
ENSG00000197233	0	0	0	0	0	0	0	0	0	0	0	0	OR1J2	olfactory receptor family 1 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:8209]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197238	0	0	0	0	1.174	0	0	0	0	0	8	0	H4C11	H4 clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4785]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000197241	0	0	0	0	0	0	0	0	0	0	0	0	SLC2A7	solute carrier family 2 member 7 [Source:HGNC Symbol;Acc:HGNC:13445]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0051119//sugar transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0015749//monosaccharide transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000197245	0	0	0	0.047	0	0	0	0	0	2.01	0	0	FAM110D	family with sequence similarity 110 member D [Source:HGNC Symbol;Acc:HGNC:25860]	-	-	-	-	-	-	-	--
ENSG00000197249	80.325	81.558	87.371	91.425	84.658	94.725	2684	2822	2220	2277	2426	2319	SERPINA1	serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03984	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031093//platelet alpha granule lumen;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding	GO:0006953//acute-phase response;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000197253	0	0	0	0	0.098	0	0	0	0	0	2	0	TPSB2	tryptase beta 2 [Source:HGNC Symbol;Acc:HGNC:14120]	Human Diseases	Infectious disease: viral	ko05164//Influenza A	K01340	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000197256	36.677	37.518	33.153	32.112	33.47	34.508	2605	2479	1696	1676	1743	1696	KANK2	KN motif and ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:29300]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0035023//regulation of Rho protein signal transduction;GO:0043069//negative regulation of programmed cell death;GO:0070563//negative regulation of vitamin D receptor signaling pathway;GO:0072073//kidney epithelium development;GO:0090521//glomerular visceral epithelial cell migration;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000197261	0.466	0.241	0.354	0.091	0.22	0.086	15	9	8	2	6	2	C6orf141	chromosome 6 open reading frame 141 [Source:HGNC Symbol;Acc:HGNC:21351]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000197265	13.864	12.053	9.458	11.065	8.101	8.761	500	439	250	297	248	231	GTF2E2	general transcription factor IIE subunit 2 [Source:HGNC Symbol;Acc:HGNC:4651]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors	K03137;K03137	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005673//transcription factor TFIIE complex;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter	--
ENSG00000197272	0	0	0	0	0	0	0	0	0	0	0	0	IL27	interleukin 27 [Source:HGNC Symbol;Acc:HGNC:19157]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04659//Th17 cell differentiation	K22629;K22629	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005829//cytosol	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0045523//interleukin-27 receptor binding	GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0009617//response to bacterium;GO:0032729//positive regulation of interferon-gamma production;GO:0042129//regulation of T cell proliferation;GO:0045087//innate immune response;GO:0045625//regulation of T-helper 1 cell differentiation;GO:0050688//regulation of defense response to virus	--
ENSG00000197273	0	0	0	0	0	0	0	0	0	0	0	0	GUCA2A	guanylate cyclase activator 2A [Source:HGNC Symbol;Acc:HGNC:4682]	-	-	-	-	GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0030250//guanylate cyclase activator activity	GO:0007165//signal transduction;GO:0031284//positive regulation of guanylate cyclase activity	--
ENSG00000197275	1.908	0.909	0.622	0.962	0.797	1.342	112.12	58.24	29.28	45.43	39.05	58.28	RAD54B	RAD54 homolog B [Source:HGNC Symbol;Acc:HGNC:17228]	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10877	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015616//DNA translocase activity;GO:0016787//hydrolase activity;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006312//mitotic recombination;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus;GO:0007131//reciprocal meiotic recombination;GO:0008340//determination of adult lifespan;GO:0009410//response to xenobiotic stimulus;GO:0010212//response to ionizing radiation;GO:0032508//DNA duplex unwinding	--
ENSG00000197279	0.74	0.614	0.563	0.4	0.568	0.576	30	25	18	12	22	17	ZNF165	zinc finger protein 165 [Source:HGNC Symbol;Acc:HGNC:12953]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000197283	7.382	6.694	7.748	8.166	8.591	11.178	613	579	475	491	625	700	SYNGAP1	synaptic Ras GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:11497]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17631	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0043198//dendritic shaft;GO:0098978//glutamatergic synapse	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0007389//pattern specification process;GO:0008542//visual learning;GO:0016358//dendrite development;GO:0043087//regulation of GTPase activity;GO:0043113//receptor clustering;GO:0043408//regulation of MAPK cascade;GO:0043524//negative regulation of neuron apoptotic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048167//regulation of synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0050771//negative regulation of axonogenesis;GO:0050803//regulation of synapse structure or activity;GO:0098880//maintenance of postsynaptic specialization structure	--
ENSG00000197296	5.802	6.343	7.772	6.497	6.806	6.371	557	612	551	462	552	445	FITM2	fat storage inducing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:16135]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0010945//CoA pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0017129//triglyceride binding;GO:0019992//diacylglycerol binding	GO:0006629//lipid metabolic process;GO:0007010//cytoskeleton organization;GO:0008654//phospholipid biosynthetic process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010890//positive regulation of sequestering of triglyceride;GO:0019915//lipid storage;GO:0022604//regulation of cell morphogenesis;GO:0030730//sequestering of triglyceride;GO:0034389//lipid droplet organization;GO:0035356//cellular triglyceride homeostasis;GO:0036115//fatty-acyl-CoA catabolic process;GO:0055088//lipid homeostasis;GO:0140042//lipid droplet formation	--
ENSG00000197299	0.246	0.27	0.204	0.213	0.162	0.206	23	24	15	14	14	14	BLM	BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058]	Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03440//Homologous recombination	K10901;K10901	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0016605//PML body;GO:0031422//RecQ family helicase-topoisomerase III complex;GO:0032991//protein-containing complex"	"GO:0000166//nucleotide binding;GO:0000400//four-way junction DNA binding;GO:0000403//Y-form DNA binding;GO:0000405//bubble DNA binding;GO:0002039//p53 binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0008270//zinc ion binding;GO:0009378//four-way junction helicase activity;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043138//3'-5' DNA helicase activity;GO:0046872//metal ion binding;GO:0051880//G-quadruplex DNA binding;GO:0061749//forked DNA-dependent helicase activity;GO:0061821//telomeric D-loop binding;GO:0061849//telomeric G-quadruplex DNA binding;GO:1905773//8-hydroxy-2'-deoxyguanosine DNA binding;GO:1990814//DNA/DNA annealing activity"	"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000723//telomere maintenance;GO:0000724//double-strand break repair via homologous recombination;GO:0000729//DNA double-strand break processing;GO:0006260//DNA replication;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010165//response to X-ray;GO:0031297//replication fork processing;GO:0032201//telomere maintenance via semi-conservative replication;GO:0032508//DNA duplex unwinding;GO:0044237//cellular metabolic process;GO:0044806//G-quadruplex DNA unwinding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045910//negative regulation of DNA recombination;GO:0048478//replication fork protection;GO:0051259//protein complex oligomerization;GO:0051260//protein homooligomerization;GO:0051782//negative regulation of cell division;GO:0061820//telomeric D-loop disassembly;GO:0071139//resolution of recombination intermediates;GO:0071479//cellular response to ionizing radiation;GO:0072711//cellular response to hydroxyurea;GO:0072757//cellular response to camptothecin;GO:0090304//nucleic acid metabolic process;GO:0090329//regulation of DNA-dependent DNA replication;GO:0090656//t-circle formation"	--
ENSG00000197302	4.454	3.147	2.744	2.384	3.247	3.837	277	184	125.19	120	194	182	KRBOX5	KRAB box domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26987]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000197309	0	0	0	0	0	0	0	0	0	0	0	0	OR10D3	olfactory receptor family 10 subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:8168]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197312	6.534	6.355	6.192	5.396	5.989	6.393	1445.78	1348.9	1011.77	884.36	1119.5	1012.11	DDI2	DNA damage inducible 1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:24578]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0043130//ubiquitin binding	GO:0006508//proteolysis;GO:0010498//proteasomal protein catabolic process;GO:0016485//protein processing;GO:0031647//regulation of protein stability;GO:0072711//cellular response to hydroxyurea;GO:0097752//regulation of DNA stability	--
ENSG00000197321	2.483	3.126	1.985	2.415	1.751	1.832	270	342	172	144	189	150	SVIL	supervillin [Source:HGNC Symbol;Acc:HGNC:11480]	-	-	-	-	GO:0002102//podosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0036449//microtubule minus-end;GO:0042995//cell projection;GO:0043034//costamere	"GO:0003779//actin binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0051015//actin filament binding"	GO:0007010//cytoskeleton organization;GO:0007519//skeletal muscle tissue development;GO:0008154//actin polymerization or depolymerization;GO:0032467//positive regulation of cytokinesis;GO:0051014//actin filament severing;GO:0051016//barbed-end actin filament capping	--
ENSG00000197323	8.333	6.246	5.947	4.985	5.822	6.426	1176	885	615	521	692	690	TRIM33	tripartite motif containing 33 [Source:HGNC Symbol;Acc:HGNC:16290]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0070410//co-SMAD binding;GO:0070412//R-SMAD binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0016567//protein ubiquitination;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000197324	93.075	96.514	94.829	96.301	96.058	94.062	8306	8224	6373	6188	7198	6206	LRP10	LDL receptor related protein 10 [Source:HGNC Symbol;Acc:HGNC:14553]	-	-	-	-	GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005041//low-density lipoprotein particle receptor activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0006897//endocytosis;GO:0048839//inner ear development	--
ENSG00000197329	8.796	7.357	8.379	5.307	6.143	8.577	678	570	477	303	400	481	PELI1	pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0001819//positive regulation of cytokine production;GO:0008063//Toll signaling pathway;GO:0008592//regulation of Toll signaling pathway;GO:0016567//protein ubiquitination;GO:0030890//positive regulation of B cell proliferation;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032496//response to lipopolysaccharide;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043331//response to dsRNA;GO:0050868//negative regulation of T cell activation;GO:0050871//positive regulation of B cell activation;GO:0060544//regulation of necroptotic process;GO:0060546//negative regulation of necroptotic process;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000197343	15.847	13.043	12.337	11.699	12.372	13.451	923	764	544	525	581	575.95	ZNF655	zinc finger protein 655 [Source:HGNC Symbol;Acc:HGNC:30899]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle"	zf-C2H2
ENSG00000197345	14.57	14.261	14.342	11.026	11.457	14.208	207	205	150	116	137	146	MRPL21	mitochondrial ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:14479]	Genetic Information Processing	Translation	ko03010//Ribosome	K02888	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000197353	0.489	1.377	0.662	0	0.289	0	6	17	6	0	3	0	LYPD2	LY6/PLAUR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25215]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0005515//protein binding	-	--
ENSG00000197355	20.313	20.351	20.854	24.144	22.369	22.141	1397	1418	1033	1194	1291	1108	UAP1L1	UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K00972;K00972	-	GO:0003977//UDP-N-acetylglucosamine diphosphorylase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0070569//uridylyltransferase activity	GO:0006048//UDP-N-acetylglucosamine biosynthetic process	--
ENSG00000197360	0	0	0	0	0	0	0	0	0	0	0	0	ZNF98	zinc finger protein 98 [Source:HGNC Symbol;Acc:HGNC:13174]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197361	0.059	0.22	0.299	0.128	0.224	0.174	3	7	7	3	6	4	FBXL22	F-box and leucine rich repeat protein 22 [Source:HGNC Symbol;Acc:HGNC:27537]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0030018//Z disc	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051726//regulation of cell cycle	--
ENSG00000197362	2.239	2.144	3.104	2.428	1.978	2.773	148	142	152	118	111	132	ZNF786	zinc finger protein 786 [Source:HGNC Symbol;Acc:HGNC:21806]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197363	3.057	2.815	3.262	2.847	3.652	3.63	169	137	121	110	168	144	ZNF517	zinc finger protein 517 [Source:HGNC Symbol;Acc:HGNC:27984]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197364	0	0	0	0	0	0	0	0	0	0	0	0	S100A7L2	S100 calcium binding protein A7 like 2 [Source:HGNC Symbol;Acc:HGNC:21655]	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21126	GO:0005615//extracellular space	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0048306//calcium-dependent protein binding	-	--
ENSG00000197372	5.049	3.57	4.204	3.77	3.058	3.873	242	172	119	116	115	127	ZNF675	zinc finger protein 675 [Source:HGNC Symbol;Acc:HGNC:30768]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0043508//negative regulation of JUN kinase activity;GO:0045453//bone resorption;GO:0045671//negative regulation of osteoclast differentiation;GO:0046329//negative regulation of JNK cascade;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:2000678//negative regulation of transcription regulatory region DNA binding"	zf-C2H2
ENSG00000197375	9.809	7.786	10.704	9.278	10.883	11.743	622	520	488	459	569	536	SLC22A5	solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K08202	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015226//carnitine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0042910//xenobiotic transmembrane transporter activity;GO:1901235//(R)-carnitine transmembrane transporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0009609//response to symbiotic bacterium;GO:0015697//quaternary ammonium group transport;GO:0015879//carnitine transport;GO:0055085//transmembrane transport;GO:0060731//positive regulation of intestinal epithelial structure maintenance;GO:0070715//sodium-dependent organic cation transport;GO:0150104//transport across blood-brain barrier;GO:1902270//(R)-carnitine transmembrane transport;GO:1902603//carnitine transmembrane transport;GO:1990961//xenobiotic detoxification by transmembrane export across the plasma membrane	--
ENSG00000197380	1.282	1.508	0.984	0.862	1.32	1.248	75	90	39	39	68	52	DACT3	dishevelled binding antagonist of beta catenin 3 [Source:HGNC Symbol;Acc:HGNC:30745]	-	-	-	-	GO:0005737//cytoplasm	GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0051018//protein kinase A binding;GO:0070097//delta-catenin binding	GO:0009968//negative regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000197381	3.093	2.36	2.372	2.694	2.998	2.704	346	279	193	239	292	239	ADARB1	adenosine deaminase RNA specific B1 [Source:HGNC Symbol;Acc:HGNC:226]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045202//synapse	GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0003729//mRNA binding;GO:0004000//adenosine deaminase activity;GO:0005515//protein binding;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0006382//adenosine to inosine editing;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0007274//neuromuscular synaptic transmission;GO:0008285//negative regulation of cell population proliferation;GO:0016553//base conversion or substitution editing;GO:0021610//facial nerve morphogenesis;GO:0021618//hypoglossal nerve morphogenesis;GO:0021965//spinal cord ventral commissure morphogenesis;GO:0030336//negative regulation of cell migration;GO:0035264//multicellular organism growth;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045070//positive regulation of viral genome replication;GO:0045087//innate immune response;GO:0050884//neuromuscular process controlling posture;GO:0051607//defense response to virus;GO:0051726//regulation of cell cycle;GO:0060384//innervation;GO:0060415//muscle tissue morphogenesis;GO:0061744//motor behavior;GO:0097049//motor neuron apoptotic process	--
ENSG00000197385	0.824	0.909	0.264	0.344	0.461	0.268	55	61	13	17	26	13	ZNF860	zinc finger protein 860 [Source:HGNC Symbol;Acc:HGNC:34513]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197386	7.725	7.732	8.371	7.61	8.409	8.781	2166	2175	1737	1580	1992	1646	HTT	huntingtin [Source:HGNC Symbol;Acc:HGNC:4851]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05016//Huntington disease	K04533;K04533	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005814//centriole;GO:0005829//cytosol;GO:0016234//inclusion body;GO:0030424//axon;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0099523//presynaptic cytosol;GO:0099524//postsynaptic cytosol	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0019900//kinase binding;GO:0031072//heat shock protein binding;GO:0034452//dynactin binding;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0045505//dynein intermediate chain binding;GO:0048487//beta-tubulin binding	"GO:0000132//establishment of mitotic spindle orientation;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006915//apoptotic process;GO:0007030//Golgi organization;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0031648//protein destabilization;GO:0042297//vocal learning;GO:0043065//positive regulation of apoptotic process;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0045724//positive regulation of cilium assembly;GO:0047496//vesicle transport along microtubule;GO:0099111//microtubule-based transport;GO:1903599//positive regulation of autophagy of mitochondrion;GO:1904504//positive regulation of lipophagy;GO:1905289//regulation of CAMKK-AMPK signaling cascade;GO:1905337//positive regulation of aggrephagy;GO:2000479//regulation of cAMP-dependent protein kinase activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway"	--
ENSG00000197403	0	0	0	0	0	0	0	0	0	0	0	0	OR6N1	olfactory receptor family 6 subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:15034]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197405	0.29	0.144	0.618	0.168	0.516	0.371	14	7	22	6	21	13	C5AR1	complement C5a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1338]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Immune system;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system	ko04080//Neuroactive ligand-receptor interaction;ko05171//Coronavirus disease - COVID-19;ko04613//Neutrophil extracellular trap formation;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades	K04010;K04010;K04010;K04010;K04010;K04010	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030667//secretory granule membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell	GO:0004875//complement receptor activity;GO:0004878//complement component C5a receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0001774//microglial cell activation;GO:0002430//complement receptor mediated signaling pathway;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007606//sensory perception of chemical stimulus;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0010759//positive regulation of macrophage chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0032494//response to peptidoglycan;GO:0038178//complement component C5a signaling pathway;GO:0042789//mRNA transcription by RNA polymerase II;GO:0045766//positive regulation of angiogenesis;GO:0048143//astrocyte activation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0050830//defense response to Gram-positive bacterium;GO:0050890//cognition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0097242//amyloid-beta clearance;GO:0099172//presynapse organization;GO:1902947//regulation of tau-protein kinase activity	--
ENSG00000197406	0.138	0.183	0.217	0.124	0.027	0.126	6	8	7	4	1	4	-	-	-	-	-	-	-	-	-	-
ENSG00000197408	0	0	0	0	0	0	0	0	0	0	0	0	CYP2B6	cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]	Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00590//Arachidonic acid metabolism	K17709;K17709;K17709;K17709;K17709;K17709;K17709	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008390//testosterone 16-alpha-hydroxylase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0062184//testosterone 16-beta-hydroxylase activity;GO:0062187//anandamide 8,9 epoxidase activity;GO:0062188//anandamide 11,12 epoxidase activity;GO:0062189//anandamide 14,15 epoxidase activity;GO:0101021//estrogen 2-hydroxylase activity"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042178//xenobiotic catabolic process;GO:0042180//cellular ketone metabolic process	--
ENSG00000197409	0.138	0	0	0.101	0.113	0	1.44	0	0	0.78	1	0	H3C4	H3 clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4767]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000197410	0.022	0.029	0.005	0.019	0.017	0.005	6	5	1	4	4	1	DCHS2	dachsous cadherin-related 2 [Source:HGNC Symbol;Acc:HGNC:23111]	Environmental Information Processing	Signal transduction	ko04392//Hippo signaling pathway - multiple species	K16507	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008150//biological_process;GO:0072006//nephron development;GO:0072137//condensed mesenchymal cell proliferation	--
ENSG00000197415	40.124	38.931	41.048	37.108	37.203	40.112	2245	2054	1560	1449	1528	1457	VEPH1	ventricular zone expressed PH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25735]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0010314//phosphatidylinositol-5-phosphate binding	GO:0009966//regulation of signal transduction;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060392//negative regulation of SMAD protein signal transduction	--
ENSG00000197416	0	0	0	0	0	0	0	0	0	0	0	0	FABP12	fatty acid binding protein 12 [Source:HGNC Symbol;Acc:HGNC:34524]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005504//fatty acid binding;GO:0008289//lipid binding	GO:0015908//fatty acid transport	--
ENSG00000197417	3.818	4.558	3.964	3.849	4.23	3.918	300	360	230	224	280.78	224	SHPK	sedoheptulokinase [Source:HGNC Symbol;Acc:HGNC:1492]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0050277//sedoheptulokinase activity"	"GO:0005975//carbohydrate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0016310//phosphorylation;GO:0035963//cellular response to interleukin-13;GO:0043030//regulation of macrophage activation;GO:0050727//regulation of inflammatory response;GO:0071222//cellular response to lipopolysaccharide;GO:0071353//cellular response to interleukin-4"	--
ENSG00000197428	0	0	0	0	0	0	0	0	0	0	0	0	OR51D1	olfactory receptor family 51 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:15193]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197429	3.913	3.697	4.491	3.74	3.523	3.254	253	234	204	176	187	151	IPP	intracisternal A particle-promoted polypeptide [Source:HGNC Symbol;Acc:HGNC:6108]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding	-	--
ENSG00000197430	0	0	0	0	0	0	0	0	0	0	0	0	OPALIN	oligodendrocytic myelin paranodal and inner loop protein [Source:HGNC Symbol;Acc:HGNC:20707]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044291//cell-cell contact zone	-	GO:0048713//regulation of oligodendrocyte differentiation	--
ENSG00000197437	0	0	0	0	0	0	0	0	0	0	0	0	OR13G1	olfactory receptor family 13 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:14999]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197442	1.365	1.423	1.949	1.325	2.025	1.58	146	153	154	105	183	123	MAP3K5	mitogen-activated protein kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6857]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Genetic Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Cellular community - eukaryotes;Folding, sorting and degradation;Endocrine and metabolic disease;Neurodegenerative disease;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Nervous system;Signal transduction;Signal transduction;Drug resistance: antineoplastic"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04010//MAPK signaling pathway;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05417//Lipid and atherosclerosis;ko04530//Tight junction;ko04141//Protein processing in endoplasmic reticulum;ko04932//Non-alcoholic fatty liver disease;ko05017//Spinocerebellar ataxia;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04668//TNF signaling pathway;ko01524//Platinum drug resistance	K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426;K04426	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0032991//protein-containing complex;GO:1902911//protein kinase complex;GO:1990604//IRE1-TRAF2-ASK1 complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	"GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0002931//response to ischemia;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010941//regulation of cell death;GO:0016310//phosphorylation;GO:0034198//cellular response to amino acid starvation;GO:0034976//response to endoplasmic reticulum stress;GO:0038066//p38MAPK cascade;GO:0042060//wound healing;GO:0043065//positive regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0045087//innate immune response;GO:0045663//positive regulation of myoblast differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046330//positive regulation of JNK cascade;GO:0051403//stress-activated MAPK cascade;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0070301//cellular response to hydrogen peroxide;GO:0071356//cellular response to tumor necrosis factor;GO:0072577//endothelial cell apoptotic process;GO:0090398//cellular senescence;GO:0097190//apoptotic signaling pathway;GO:0097300//programmed necrotic cell death;GO:1900745//positive regulation of p38MAPK cascade;GO:1901216//positive regulation of neuron death;GO:1902170//cellular response to reactive nitrogen species;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation"	--
ENSG00000197444	13.36	15.745	15.203	19.442	18.531	15.787	1027	1216	862	1107	1202	883	OGDHL	oxoglutarate dehydrogenase L [Source:HGNC Symbol;Acc:HGNC:25590]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00164;K00164;K00164	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045252//oxoglutarate dehydrogenase complex	"GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0030976//thiamine pyrophosphate binding;GO:0046872//metal ion binding"	GO:0006096//glycolytic process;GO:0006099//tricarboxylic acid cycle;GO:0006103//2-oxoglutarate metabolic process	--
ENSG00000197446	0	0	0.092	0	0	0	0	0	1	0	0	0	CYP2F1	cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632]	Human Diseases;Metabolism	Cancer: overview;Xenobiotics biodegradation and metabolism	ko05208//Chemical carcinogenesis - reactive oxygen species;ko00980//Metabolism of xenobiotics by cytochrome P450	K07416;K07416	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0006082//organic acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0019373//epoxygenase P450 pathway;GO:1901170//naphthalene catabolic process	--
ENSG00000197448	74.406	78.185	75.972	89.173	74.55	77.851	1687	1776	1277	1483	1440	1289	GSTK1	glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906]	Metabolism;Cellular Processes;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K13299;K13299;K13299;K13299;K13299;K13299	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity	GO:0006749//glutathione metabolic process;GO:0030855//epithelial cell differentiation;GO:0098869//cellular oxidant detoxification	--
ENSG00000197451	58.522	60.198	61.959	57.86	55.561	63.287	2093	2168	1632	1529	1679	1646	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0045293//mRNA editing complex;GO:0071598//neuronal ribonucleoprotein granule;GO:0090575//RNA polymerase II transcription regulator complex;GO:0110165//cellular anatomical entity;GO:1990124//messenger ribonucleoprotein complex;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding	"GO:0001837//epithelial to mesenchymal transition;GO:0010468//regulation of gene expression;GO:0016556//mRNA modification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060341//regulation of cellular localization;GO:0071230//cellular response to amino acid stimulus;GO:1901537//positive regulation of DNA demethylation;GO:1904580//regulation of intracellular mRNA localization;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000197454	0	0	0	0	0	0	0	0	0	0	0	0	OR2L5	olfactory receptor family 2 subfamily L member 5 [Source:HGNC Symbol;Acc:HGNC:15011]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197457	5.72	4.417	5.911	7.513	6.422	5.552	238	207	199	209	253	168	STMN3	stathmin 3 [Source:HGNC Symbol;Acc:HGNC:15926]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030424//axon;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0019904//protein domain specific binding	GO:0001835//blastocyst hatching;GO:0007019//microtubule depolymerization;GO:0007399//nervous system development;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development;GO:0035021//negative regulation of Rac protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0051493//regulation of cytoskeleton organization	--
ENSG00000197461	5.79	6.209	6.674	4.784	5.213	5.19	266	284	211	154	197	166	PDGFA	platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Cardiovascular disease;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma	K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359;K04359	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005902//microvillus;GO:0009986//cell surface;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:1990265//platelet-derived growth factor complex	GO:0005161//platelet-derived growth factor receptor binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0048018//receptor ligand activity;GO:0048407//platelet-derived growth factor binding;GO:0070851//growth factor receptor binding	GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0001775//cell activation;GO:0001942//hair follicle development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0009611//response to wounding;GO:0009887//animal organ morphogenesis;GO:0010033//response to organic substance;GO:0010035//response to inorganic substance;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:0010544//negative regulation of platelet activation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014910//regulation of smooth muscle cell migration;GO:0030031//cell projection assembly;GO:0030036//actin cytoskeleton organization;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032355//response to estradiol;GO:0032526//response to retinoic acid;GO:0032956//regulation of actin cytoskeleton organization;GO:0035790//platelet-derived growth factor receptor-alpha signaling pathway;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0042060//wound healing;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043588//skin development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048146//positive regulation of fibroblast proliferation;GO:0048286//lung alveolus development;GO:0048839//inner ear development;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0050919//negative chemotaxis;GO:0051781//positive regulation of cell division;GO:0051897//positive regulation of protein kinase B signaling;GO:0060683//regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1990401//embryonic lung development	--
ENSG00000197465	1.785	0.711	1.405	1.273	0.677	0.987	52	25	36	33	20	25	GYPE	glycophorin E (MNS blood group) [Source:HGNC Symbol;Acc:HGNC:4705]	Human Diseases	Infectious disease: parasitic	ko05144//Malaria	K20925	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000197467	0.026	0.045	0.521	0	0.093	0.049	1	1	9	0	3	1	COL13A1	collagen type XIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2190]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K16617	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005600//collagen type XIII trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001763//morphogenesis of a branching structure;GO:0001958//endochondral ossification;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0030903//notochord development;GO:0098609//cell-cell adhesion	--
ENSG00000197471	0	0.014	0	0	0	0	0	2	0	0	0	0	SPN	sialophorin [Source:HGNC Symbol;Acc:HGNC:11249]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06477	GO:0001931//uropod;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005902//microvillus;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016605//PML body;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding	GO:0002296//T-helper 1 cell lineage commitment;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007162//negative regulation of cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0032609//interferon-gamma production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042130//negative regulation of T cell proliferation;GO:0042742//defense response to bacterium;GO:0050776//regulation of immune response;GO:0050863//regulation of T cell activation;GO:0050901//leukocyte tethering or rolling;GO:2000404//regulation of T cell migration;GO:2000406//positive regulation of T cell migration	--
ENSG00000197472	0.529	0.599	0.411	0.178	0.178	0.428	14	23	8	3	9	9	ZNF695	zinc finger protein 695 [Source:HGNC Symbol;Acc:HGNC:30954]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197479	0.2	0.236	0.204	0.141	0.098	0.049	16.31	17.09	13	9	7.04	3.07	PCDHB11	protocadherin beta 11 [Source:HGNC Symbol;Acc:HGNC:8682]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007399//nervous system development;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000197483	1.381	3.667	3.327	1.705	2.963	2.598	102	115	92	73	142	96	ZNF628	zinc finger protein 628 [Source:HGNC Symbol;Acc:HGNC:28054]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis"	zf-C2H2
ENSG00000197487	0	0	0	0	0	0	0	0	0	0	0	0	GALP	galanin like peptide [Source:HGNC Symbol;Acc:HGNC:24840]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25482	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0005179//hormone activity;GO:0005515//protein binding	GO:0007218//neuropeptide signaling pathway;GO:0008150//biological_process;GO:0009725//response to hormone;GO:0032098//regulation of appetite;GO:0032868//response to insulin;GO:0035821//modulation of process of other organism;GO:0042595//behavioral response to starvation;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000197496	9.271	9.157	10.337	8.242	7.979	8.669	793	807	610	516	591	553	SLC2A10	solute carrier family 2 member 10 [Source:HGNC Symbol;Acc:HGNC:13444]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005351//carbohydrate:proton symporter activity;GO:0022857//transmembrane transporter activity;GO:0033300//dehydroascorbic acid transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0008645//hexose transmembrane transport;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0015757//galactose transmembrane transport;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032683//negative regulation of connective tissue growth factor production;GO:0043588//skin development;GO:0045454//cell redox homeostasis;GO:0055085//transmembrane transport;GO:0060392//negative regulation of SMAD protein signal transduction;GO:0060840//artery development;GO:0070837//dehydroascorbic acid transport;GO:0072498//embryonic skeletal joint development;GO:0098708//glucose import across plasma membrane;GO:0150104//transport across blood-brain barrier;GO:1902600//proton transmembrane transport;GO:1902729//negative regulation of proteoglycan biosynthetic process;GO:1902730//positive regulation of proteoglycan biosynthetic process;GO:1903053//regulation of extracellular matrix organization;GO:1904659//glucose transmembrane transport;GO:2001045//negative regulation of integrin-mediated signaling pathway	--
ENSG00000197497	0.468	0.324	0.194	0.28	0.24	0.087	31	22	10	17	14	3	ZNF665	zinc finger protein 665 [Source:HGNC Symbol;Acc:HGNC:25885]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197498	5.653	5.057	4.383	4.129	5.788	5.352	312	293	193	225	270	229	RPF2	ribosome production factor 2 homolog [Source:HGNC Symbol;Acc:HGNC:20870]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008097//5S rRNA binding;GO:0019843//rRNA binding	"GO:0000027//ribosomal large subunit assembly;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000470//maturation of LSU-rRNA;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1902570//protein localization to nucleolus"	--
ENSG00000197506	0.35	0.242	0.158	0.066	0.115	0.093	36	25	12	5	10	7	SLC28A3	solute carrier family 28 member 3 [Source:HGNC Symbol;Acc:HGNC:16484]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane	GO:0005337//nucleoside transmembrane transporter activity;GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005415//nucleoside:sodium symporter activity;GO:0015213//uridine transmembrane transporter activity;GO:0015293//symporter activity;GO:0015389//pyrimidine- and adenine-specific:sodium symporter activity;GO:0015390//purine-specific nucleoside:sodium symporter activity	GO:0015855//pyrimidine nucleobase transport;GO:0015860//purine nucleoside transmembrane transport;GO:0015862//uridine transport;GO:0015864//pyrimidine nucleoside transport;GO:0035725//sodium ion transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:1901642//nucleoside transmembrane transport;GO:1904823//purine nucleobase transmembrane transport	--
ENSG00000197520	0	0	0	0	0	0	0	0	0	0	0	0	FAM177B	family with sequence similarity 177 member B [Source:HGNC Symbol;Acc:HGNC:34395]	-	-	-	-	-	-	-	--
ENSG00000197530	16.707	15.077	16.898	18.414	19.585	17.906	919	866	718	764	819	745	MIB2	MIB E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:30577]	Human Diseases	Cardiovascular disease	ko05417//Lipid and atherosclerosis	K10645	GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol	GO:0003779//actin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling	--
ENSG00000197532	0	0	0	0	0	0	0	0	0	0	0	0	OR6Y1	olfactory receptor family 6 subfamily Y member 1 [Source:HGNC Symbol;Acc:HGNC:14823]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197535	12.311	8.653	8.098	5.587	7.312	6.483	2125	1543	1123	798	1013	997	MYO5A	myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10357	GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005777//peroxisome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005884//actin filament;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0030426//growth cone;GO:0031982//vesicle;GO:0032433//filopodium tip;GO:0032593//insulin-responsive compartment;GO:0042470//melanosome;GO:0043005//neuron projection;GO:0055037//recycling endosome;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding	GO:0006892//post-Golgi vesicle-mediated transport;GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030048//actin filament-based movement;GO:0030050//vesicle transport along actin filament;GO:0032402//melanosome transport;GO:0032869//cellular response to insulin stimulus;GO:0072659//protein localization to plasma membrane	--
ENSG00000197540	0	0	0.071	0	0	0	0	0	1	0	0	0	GZMM	granzyme M [Source:HGNC Symbol;Acc:HGNC:4712]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane	GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0001913//T cell mediated cytotoxicity;GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0008219//cell death;GO:0019835//cytolysis;GO:0045087//innate immune response	--
ENSG00000197548	13.714	13.195	13.784	13.862	16.757	12.638	397.23	451.9	346.84	326.26	436.83	328.06	ATG7	autophagy related 7 [Source:HGNC Symbol;Acc:HGNC:16935]	Organismal Systems;Cellular Processes;Cellular Processes;Cellular Processes	Immune system;Transport and catabolism;Cell growth and death;Transport and catabolism	ko04613//Neutrophil extracellular trap formation;ko04140//Autophagy - animal;ko04216//Ferroptosis;ko04136//Autophagy - other	K08337;K08337;K08337;K08337	GO:0000407//phagophore assembly site;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005930//axoneme;GO:0034774//secretory granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0019778//Atg12 activating enzyme activity;GO:0019779//Atg8 activating enzyme activity;GO:0042803//protein homodimerization activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006497//protein lipidation;GO:0006501//C-terminal protein lipidation;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0015031//protein transport;GO:0016236//macroautophagy;GO:0031401//positive regulation of protein modification process;GO:0032446//protein modification by small protein conjugation;GO:0034727//piecemeal microautophagy of the nucleus;GO:0039521//suppression by virus of host autophagy;GO:0042752//regulation of circadian rhythm;GO:0043065//positive regulation of apoptotic process;GO:0044805//late nucleophagy;GO:0045732//positive regulation of protein catabolic process;GO:0048511//rhythmic process;GO:0051607//defense response to virus;GO:0071455//cellular response to hyperoxia	--
ENSG00000197555	5.424	5.653	6.054	3.899	5.594	5.504	780	808	613	445	637	600	SIPA1L1	signal induced proliferation associated 1 like 1 [Source:HGNC Symbol;Acc:HGNC:20284]	Environmental Information Processing	Signal transduction	ko04015//Rap1 signaling pathway	K17701	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045202//synapse	GO:0003674//molecular_function;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0008150//biological_process;GO:0031532//actin cytoskeleton reorganization;GO:0043087//regulation of GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0048814//regulation of dendrite morphogenesis;GO:0050770//regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0061001//regulation of dendritic spine morphogenesis;GO:0090630//activation of GTPase activity	--
ENSG00000197557	3.875	3.524	3.013	2.466	2.688	2.717	461.62	421.98	265.1	217.63	270.56	235.52	TTC30A	tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853]	-	-	-	-	GO:0005879//axonemal microtubule;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0042995//cell projection	GO:0005515//protein binding;GO:0120170//intraciliary transport particle B binding	GO:0030030//cell projection organization;GO:0042073//intraciliary transport	--
ENSG00000197561	0	0	0	0	0	0	0	0	0	0	0	0	ELANE	"elastase, neutrophil expressed [Source:HGNC Symbol;Acc:HGNC:3309]"	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Immune disease	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus	K01327;K01327;K01327	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0009986//cell surface;GO:0017053//transcription repressor complex;GO:0030141//secretory granule;GO:0031410//cytoplasmic vesicle;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0045335//phagocytic vesicle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0003714//transcription corepressor activity;GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0019955//cytokine binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001878//response to yeast;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002812//biosynthetic process of antibacterial peptides active against Gram-negative bacteria;GO:0006508//proteolysis;GO:0006874//cellular calcium ion homeostasis;GO:0006909//phagocytosis;GO:0009411//response to UV;GO:0022617//extracellular matrix disassembly;GO:0030163//protein catabolic process;GO:0032496//response to lipopolysaccharide;GO:0032682//negative regulation of chemokine production;GO:0032717//negative regulation of interleukin-8 production;GO:0032757//positive regulation of interleukin-8 production;GO:0042742//defense response to bacterium;GO:0043406//positive regulation of MAP kinase activity;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0050778//positive regulation of immune response;GO:0050832//defense response to fungus;GO:0050900//leukocyte migration;GO:0050922//negative regulation of chemotaxis;GO:0070269//pyroptosis;GO:0070945//neutrophil-mediated killing of gram-negative bacterium;GO:0070947//neutrophil-mediated killing of fungus;GO:1903238//positive regulation of leukocyte tethering or rolling	--
ENSG00000197562	5.08	6.502	6.941	6.739	7.182	7.554	273	333	264	278	321	279	RAB40C	"RAB40C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18285]"	-	-	-	-	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0072659//protein localization to plasma membrane	--
ENSG00000197563	15.577	13.492	15.606	14.341	14.319	14.466	1294.94	1166	895	819	1045.62	849.1	PIGN	phosphatidylinositol glycan anchor biosynthesis class N [Source:HGNC Symbol;Acc:HGNC:8967]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05285;K05285	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016740//transferase activity;GO:0051377//mannose-ethanolamine phosphotransferase activity	GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane	--
ENSG00000197565	0.462	0.562	0.635	0.584	0.599	0.593	64	78	65	60	69	60	COL4A6	collagen type IV alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:2208]	Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Digestive system;Endocrine and metabolic disease;Cancer: specific types;Signaling molecules and interaction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05222//Small cell lung cancer;ko04512//ECM-receptor interaction	K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237;K06237	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005587//collagen type IV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0071230//cellular response to amino acid stimulus	--
ENSG00000197566	1.41	1.063	1.266	1.105	0.928	1.422	124	94	59	72	69	91	ZNF624	zinc finger protein 624 [Source:HGNC Symbol;Acc:HGNC:29254]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197576	0	0	0	0	0	0	0	0	0	0	0	0	HOXA4	homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000197579	6.981	5.865	5.701	3.695	4.471	6.101	571.89	482	341	223	312	371	TOPORS	"TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:21653]"	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0000922//spindle pole;GO:0000930//gamma-tubulin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005814//centriole;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0030496//midbody;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body	GO:0003677//DNA binding;GO:0003823//antigen binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0044547//DNA topoisomerase binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010842//retina layer formation;GO:0016925//protein sumoylation;GO:0034504//protein localization to nucleus;GO:0035845//photoreceptor cell outer segment organization;GO:0042127//regulation of cell population proliferation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046548//retinal rod cell development;GO:0046549//retinal cone cell development;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0051457//maintenance of protein location in nucleus;GO:0070936//protein K48-linked ubiquitination"	--
ENSG00000197580	1.821	2.581	3.508	4.528	2.419	5.032	71	86	80	80	84	83	BCO2	beta-carotene oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:18503]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	"GO:0003834//beta-carotene 15,15'-dioxygenase activity;GO:0010436//carotenoid dioxygenase activity;GO:0010437//9,10 (9', 10')-carotenoid-cleaving dioxygenase activity;GO:0016491//oxidoreductase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0102076//beta,beta-carotene-9',10'-cleaving oxygenase activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0016116//carotenoid metabolic process;GO:0016119//carotene metabolic process;GO:0016121//carotene catabolic process;GO:0016122//xanthophyll metabolic process;GO:0016124//xanthophyll catabolic process;GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0062172//lutein catabolic process;GO:1901176//lycopene catabolic process;GO:1901826//zeaxanthin catabolic process;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000197584	0	0.118	0.029	0.029	0.022	0.052	0	2	1	1	1	2	KCNMB2	potassium calcium-activated channel subfamily M regulatory beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:6286]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K04938;K04938;K04938	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008200//ion channel inhibitor activity;GO:0015269//calcium-activated potassium channel activity;GO:0015459//potassium channel regulator activity	GO:0001508//action potential;GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0019228//neuronal action potential;GO:0019229//regulation of vasoconstriction;GO:0071805//potassium ion transmembrane transport	--
ENSG00000197586	6.559	8.38	8.31	11.766	10.596	12.143	344	409	313	397	435	349	ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 [Source:HGNC Symbol;Acc:HGNC:3368]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01511;K01511;K01511	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0004382//guanosine-diphosphatase activity;GO:0005524//ATP binding;GO:0008894//guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0036384//cytidine-diphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:1990003//inosine-diphosphatase activity"	GO:0009134//nucleoside diphosphate catabolic process;GO:0016311//dephosphorylation;GO:0032026//response to magnesium ion;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0051592//response to calcium ion	--
ENSG00000197587	3.316	3.658	2.417	1.905	2.747	2.488	279	314	165	109	190	145	DMBX1	diencephalon/mesencephalon homeobox 1 [Source:HGNC Symbol;Acc:HGNC:19026]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0008343//adult feeding behavior;GO:0008344//adult locomotory behavior;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048589//developmental growth"	Homeobox
ENSG00000197591	0	0	0	0	0	0	0	0	0	0	0	0	OR11L1	olfactory receptor family 11 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:14998]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197594	0.523	0.542	0.32	0.338	0.427	0.309	41	50	28	24	46	21	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:3356]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00500//Starch and sucrose metabolism;ko00760//Nicotinate and nicotinamide metabolism;ko00770//Pantothenate and CoA biosynthesis;ko00740//Riboflavin metabolism	K01513;K01513;K01513;K01513;K01513;K01513;K01513	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane	GO:0003676//nucleic acid binding;GO:0003824//catalytic activity;GO:0004527//exonuclease activity;GO:0004528//phosphodiesterase I activity;GO:0004551//nucleotide diphosphatase activity;GO:0005044//scavenger receptor activity;GO:0005158//insulin receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030247//polysaccharide binding;GO:0035529//NADH pyrophosphatase activity;GO:0036218//dTTP diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0106177//cyclic-GMP-AMP hydrolase activity	GO:0006091//generation of precursor metabolites and energy;GO:0006796//phosphate-containing compound metabolic process;GO:0006897//endocytosis;GO:0006955//immune response;GO:0009143//nucleoside triphosphate catabolic process;GO:0010035//response to inorganic substance;GO:0010467//gene expression;GO:0016311//dephosphorylation;GO:0030282//bone mineralization;GO:0030308//negative regulation of cell growth;GO:0030318//melanocyte differentiation;GO:0030500//regulation of bone mineralization;GO:0030502//negative regulation of bone mineralization;GO:0030505//inorganic diphosphate transport;GO:0030643//cellular phosphate ion homeostasis;GO:0030730//sequestering of triglyceride;GO:0031214//biomineral tissue development;GO:0031953//negative regulation of protein autophosphorylation;GO:0032869//cellular response to insulin stimulus;GO:0033198//response to ATP;GO:0045599//negative regulation of fat cell differentiation;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0046034//ATP metabolic process;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0055062//phosphate ion homeostasis;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0110148//biomineralization;GO:1990787//negative regulation of hh target transcription factor activity	--
ENSG00000197599	0	0.019	0.277	0	0.113	0	0	1	3	0	3	0	CCDC154	coiled-coil domain containing 154 [Source:HGNC Symbol;Acc:HGNC:34454]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome	-	GO:0035630//bone mineralization involved in bone maturation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0044691//tooth eruption;GO:0045453//bone resorption	--
ENSG00000197601	9.171	5.615	6.487	5.489	7.313	8.875	944	601	454	402	535	586	FAR1	fatty acyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:26222]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13356	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity;GO:0102965//alcohol-forming fatty acyl-CoA reductase activity	GO:0006629//lipid metabolic process;GO:0008611//ether lipid biosynthetic process;GO:0010025//wax biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:1901568//fatty acid derivative metabolic process	--
ENSG00000197603	4.224	2.502	2.58	1.925	2.459	2.473	859	501	386	287	404	348	CPLANE1	ciliogenesis and planar polarity effector 1 [Source:HGNC Symbol;Acc:HGNC:25801]	-	-	-	-	GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0042995//cell projection	GO:0005515//protein binding	GO:0001736//establishment of planar polarity;GO:0001822//kidney development;GO:0003279//cardiac septum development;GO:0003281//ventricular septum development;GO:0007507//heart development;GO:0021549//cerebellum development;GO:0030030//cell projection organization;GO:0042733//embryonic digit morphogenesis;GO:0060021//roof of mouth development;GO:0060271//cilium assembly;GO:0060976//coronary vasculature development;GO:1904491//protein localization to ciliary transition zone	--
ENSG00000197608	2.113	1.852	1.308	1.104	1.702	1.642	159	149	72	64	110	91	ZNF841	zinc finger protein 841 [Source:HGNC Symbol;Acc:HGNC:27611]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197614	1.695	2.825	2.162	1.653	1.535	0.834	83	96	55	55	61	26.02	MFAP5	microfibril associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29673]	-	-	-	-	GO:0001527//microfibril;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0110165//cellular anatomical entity	GO:0005201//extracellular matrix structural constituent	GO:0048048//embryonic eye morphogenesis;GO:0060216//definitive hemopoiesis;GO:0097435//supramolecular fiber organization	--
ENSG00000197616	0.016	0.008	0.022	0	0	0	2	1	2	0	0	0	MYH6	myosin heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:7576]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Cardiovascular disease;Circulatory system;Cardiovascular disease;Endocrine system;Cardiovascular disease;Circulatory system	ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05416//Viral myocarditis;ko04919//Thyroid hormone signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K17751;K17751;K17751;K17751;K17751;K17751;K17751	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0032982//myosin filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0017018//myosin phosphatase activity;GO:0019901//protein kinase binding;GO:0051015//actin filament binding	GO:0001701//in utero embryonic development;GO:0002026//regulation of the force of heart contraction;GO:0002027//regulation of heart rate;GO:0006470//protein dephosphorylation;GO:0006936//muscle contraction;GO:0006941//striated muscle contraction;GO:0007512//adult heart development;GO:0007522//visceral muscle development;GO:0008016//regulation of heart contraction;GO:0008217//regulation of blood pressure;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030048//actin filament-based movement;GO:0030049//muscle filament sliding;GO:0030239//myofibril assembly;GO:0043462//regulation of ATPase activity;GO:0045214//sarcomere organization;GO:0046034//ATP metabolic process;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055013//cardiac muscle cell development;GO:0060048//cardiac muscle contraction;GO:0060420//regulation of heart growth	--
ENSG00000197617	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000197619	7.262	3.166	3.305	2.577	3.66	3.186	329	207	175	130	185	172	ZNF615	zinc finger protein 615 [Source:HGNC Symbol;Acc:HGNC:24740]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197620	9.34	10.035	10.476	9.599	9.562	10.563	297.24	313.67	247.27	218.56	253.79	238.52	EOLA1	endothelium and lymphocyte associated ASCH domain 1 [Source:HGNC Symbol;Acc:HGNC:28089]	-	-	-	-	-	GO:0005515//protein binding	GO:0010468//regulation of gene expression;GO:0032675//regulation of interleukin-6 production	--
ENSG00000197622	10.862	10.968	11.894	11.059	9.59	12.33	684.76	698.41	553	517.04	513.67	565.92	CDC42SE1	CDC42 small effector 1 [Source:HGNC Symbol;Acc:HGNC:17719]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0005095//GTPase inhibitor activity;GO:0031267//small GTPase binding	GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0035023//regulation of Rho protein signal transduction;GO:0043086//negative regulation of catalytic activity	--
ENSG00000197629	0	0	0	0	0.09	0	0	0	0	0	7	0	MPEG1	macrophage expressed 1 [Source:HGNC Symbol;Acc:HGNC:29619]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0045335//phagocytic vesicle	-	GO:0002376//immune system process;GO:0035915//pore formation in membrane of other organism;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000197632	0.051	0	0.103	0.272	0	0	2	0	3	3	0	0	SERPINB2	serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K19821	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0042060//wound healing;GO:0042730//fibrinolysis;GO:0043066//negative regulation of apoptotic process	--
ENSG00000197635	2.771	2.852	1.256	4.251	4.511	3.498	204	213	67	233	284	179	DPP4	dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K01278	GO:0005576//extracellular region;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0031258//lamellipodium membrane;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0046581//intercellular canaliculus;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0001618//virus receptor activity;GO:0002020//protease binding;GO:0004177//aminopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045499//chemorepellent activity	GO:0001662//behavioral fear response;GO:0001666//response to hypoxia;GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0008284//positive regulation of cell population proliferation;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0016486//peptide hormone processing;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0031295//T cell costimulation;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0035641//locomotory exploration behavior;GO:0036343//psychomotor behavior;GO:0042110//T cell activation;GO:0043542//endothelial cell migration;GO:0046718//viral entry into host cell;GO:0046813//receptor-mediated virion attachment to host cell;GO:0050919//negative chemotaxis;GO:0061025//membrane fusion;GO:0090024//negative regulation of neutrophil chemotaxis;GO:0120116//glucagon processing	--
ENSG00000197641	0	0	0	0	0	0	0	0	0	0	0	0	SERPINB13	serpin family B member 13 [Source:HGNC Symbol;Acc:HGNC:8944]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0009411//response to UV;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis;GO:1902173//negative regulation of keratinocyte apoptotic process	--
ENSG00000197646	0.297	0.217	0.295	0	0.07	0.054	15	11	11	0	3	2	PDCD1LG2	programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06708	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0032689//negative regulation of interferon-gamma production;GO:0032693//negative regulation of interleukin-10 production;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0046007//negative regulation of activated T cell proliferation;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000197647	1.653	1.519	0.956	1.429	1.152	1.212	79	74	34	51	47	42	ZNF433	zinc finger protein 433 [Source:HGNC Symbol;Acc:HGNC:20811]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197651	0	0	0	0	0	0	0	0	0	0	0	0	CCER1	coiled-coil glutamate rich protein 1 [Source:HGNC Symbol;Acc:HGNC:28373]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000197653	0.119	0.062	0.355	0.061	0.025	0.019	33	16	27	12	6	4	DNAH10	dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease	K10408;K10408;K10408	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030286//dynein complex;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008569//minus-end-directed microtubule motor activity;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007018//microtubule-based movement	--
ENSG00000197658	0	0	0	0	0	0	0	0	0	0	0	0	SLC22A24	solute carrier family 22 member 24 [Source:HGNC Symbol;Acc:HGNC:28542]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0006629//lipid metabolic process;GO:0006811//ion transport;GO:0008202//steroid metabolic process;GO:0015711//organic anion transport;GO:0035382//sterol transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000197674	0.067	0.199	0.136	0.361	0.198	0.229	2	6	3	8	5	5	OR51C1P	olfactory receptor family 51 subfamily C member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:15191]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197683	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP26-1	keratin associated protein 26-1 [Source:HGNC Symbol;Acc:HGNC:33760]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000197694	66.759	70.902	63.667	63.523	67.407	56.39	10790	11285	7554	7551	9176	6514	SPTAN1	"spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]"	Cellular Processes	Cell growth and death	ko04210//Apoptosis	K06114	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0008091//spectrin;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0035580//specific granule lumen;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043232//intracellular non-membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1903561//extracellular vesicle;GO:1904724//tertiary granule lumen	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0051693//actin filament capping	--
ENSG00000197696	6.556	5.233	7.555	3.706	6.161	5.496	99	80	84	44	78	63	NMB	neuromedin B [Source:HGNC Symbol;Acc:HGNC:7842]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05223	GO:0005576//extracellular region;GO:0043005//neuron projection	GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding;GO:0031710//neuromedin B receptor binding	GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0046887//positive regulation of hormone secretion;GO:0046888//negative regulation of hormone secretion;GO:0050482//arachidonic acid secretion	--
ENSG00000197702	20.877	20.956	23.829	25.38	20.526	22.217	3129	3020	2327	2550	2633	2156	PARVA	parvin alpha [Source:HGNC Symbol;Acc:HGNC:14652]	Cellular Processes	Cellular community - eukaryotes	ko04510//Focal adhesion	K06275	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction	GO:0003779//actin binding;GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0001525//angiogenesis;GO:0002040//sprouting angiogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0008360//regulation of cell shape;GO:0030030//cell projection organization;GO:0030031//cell projection assembly;GO:0031532//actin cytoskeleton reorganization;GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043086//negative regulation of catalytic activity;GO:0050821//protein stabilization;GO:0060271//cilium assembly;GO:0070252//actin-mediated cell contraction;GO:0071670//smooth muscle cell chemotaxis	--
ENSG00000197705	0.227	0.146	0.306	0.274	0.24	0.295	18	13	20	18	18	19	KLHL14	kelch like family member 14 [Source:HGNC Symbol;Acc:HGNC:29266]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016235//aggresome;GO:0043005//neuron projection;GO:0043025//neuronal cell body	GO:0005515//protein binding	-	--
ENSG00000197706	0.01	0	0	0	0.006	0	2	0	0	0	1	0	OR6C74	olfactory receptor family 6 subfamily C member 74 [Source:HGNC Symbol;Acc:HGNC:31303]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197712	23.033	20.834	16.546	11.383	13.852	14.779	962	890	532	355	461	410	FAM114A1	family with sequence similarity 114 member A1 [Source:HGNC Symbol;Acc:HGNC:25087]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000197713	18.985	18.342	21.243	19.946	15.498	16.039	1011.8	1005.5	737.31	645.2	625.09	662.44	RPE	ribulose-5-phosphate-3-epimerase [Source:HGNC Symbol;Acc:HGNC:10293]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00040//Pentose and glucuronate interconversions;ko00030//Pentose phosphate pathway	K01783;K01783;K01783;K01783;K01783	GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004750//ribulose-phosphate 3-epimerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019323//pentose catabolic process;GO:0044262//cellular carbohydrate metabolic process"	--
ENSG00000197714	0.655	0.598	0.509	0.883	0.754	0.564	45	48	30	27	33	24	ZNF460	zinc finger protein 460 [Source:HGNC Symbol;Acc:HGNC:21628]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197721	0	0	0	0.036	0	0	0	0	0	1	0	0	CR1L	complement C3b/C4b receptor 1 like [Source:HGNC Symbol;Acc:HGNC:2335]	Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Immune system;Infectious disease: bacterial;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Infectious disease: parasitic	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04640//Hematopoietic cell lineage;ko05140//Leishmaniasis;ko04610//Complement and coagulation cascades;ko05134//Legionellosis;ko05144//Malaria	K04011;K04011;K04011;K04011;K04011;K04011;K04011	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0043235//receptor complex	GO:0005515//protein binding	"GO:0030449//regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:1903659//regulation of complement-dependent cytotoxicity"	--
ENSG00000197724	7.744	8.733	9.788	8.64	8.371	9.452	824	913	766	688	789	702	PHF2	PHD finger protein 2 [Source:HGNC Symbol;Acc:HGNC:8920]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus"	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0035064//methylated histone binding;GO:0035575//histone H4-methyl-lysine-20 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	"GO:0001889//liver development;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006482//protein demethylation;GO:0033169//histone H3-K9 demethylation;GO:0035574//histone H4-K20 demethylation;GO:0045815//positive regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061188//negative regulation of ribosomal DNA heterochromatin assembly"	--
ENSG00000197728	104.651	106.374	104.225	112.615	104.268	111.058	1370	1402	1008	1093	1154	1059	RPS26	ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02976;K02976	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0033119//negative regulation of RNA splicing	--
ENSG00000197745	0	0	0	0	0	0	0	0	0	0	0	0	SCGB1D4	secretoglobin family 1D member 4 [Source:HGNC Symbol;Acc:HGNC:31748]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	-	--
ENSG00000197746	1427.994	1554.053	1507.845	1521.935	1528.406	1500.353	62399	67162	50050	53146	60131	51971	PSAP	prosaposin [Source:HGNC Symbol;Acc:HGNC:9498]	Cellular Processes;Metabolism	Transport and catabolism;Lipid metabolism	ko04142//Lysosome;ko00600//Sphingolipid metabolism	K12382;K12382	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0002020//protease binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0097110//scaffold protein binding;GO:1905573//ganglioside GM1 binding;GO:1905574//ganglioside GM2 binding;GO:1905575//ganglioside GM3 binding;GO:1905576//ganglioside GT1b binding;GO:1905577//ganglioside GP1c binding	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0007041//lysosomal transport;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0010506//regulation of autophagy;GO:0019216//regulation of lipid metabolic process;GO:0060736//prostate gland growth;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:1903771//positive regulation of beta-galactosidase activity;GO:1905572//ganglioside GM1 transport to membrane	--
ENSG00000197747	33.195	29.737	31.617	44.328	39.12	35.056	462	416	325	457	460	355	S100A10	S100 calcium binding protein A10 [Source:HGNC Symbol;Acc:HGNC:10487]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K17274	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0019897//extrinsic component of plasma membrane;GO:0045121//membrane raft;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0090575//RNA polymerase II transcription regulator complex;GO:0098797//plasma membrane protein complex;GO:1990665//AnxA2-p11 complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0044325//transmembrane transporter binding;GO:0048306//calcium-dependent protein binding	GO:0001765//membrane raft assembly;GO:0006900//vesicle budding from membrane;GO:0010756//positive regulation of plasminogen activation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043547//positive regulation of GTPase activity;GO:0045921//positive regulation of exocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050767//regulation of neurogenesis;GO:0051099//positive regulation of binding;GO:0051496//positive regulation of stress fiber assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0072659//protein localization to plasma membrane;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1905686//positive regulation of plasma membrane repair	--
ENSG00000197748	2.711	2.083	1.8	1.484	0.371	0.67	142	112	68	60	23	30	CFAP43	cilia and flagella associated protein 43 [Source:HGNC Symbol;Acc:HGNC:26684]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	GO:0005515//protein binding	GO:0003356//regulation of cilium beat frequency;GO:0007288//sperm axoneme assembly;GO:0007420//brain development;GO:0030030//cell projection organization;GO:0030317//flagellated sperm motility;GO:0044458//motile cilium assembly;GO:0060271//cilium assembly;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance	--
ENSG00000197753	0.164	0.034	0.074	0.048	0.02	0.169	13.69	2.89	4.56	2.99	1.39	8.23	LHFPL5	LHFPL tetraspan subfamily member 5 [Source:HGNC Symbol;Acc:HGNC:21253]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0032421//stereocilium bundle;GO:0032426//stereocilium tip	GO:0005515//protein binding	GO:0006811//ion transport;GO:0007605//sensory perception of sound;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0060088//auditory receptor cell stereocilium organization	--
ENSG00000197756	389.56	384.857	385.958	455.616	333.304	360.256	4172	4095	3093	3680	3010	2794	RPL37A	ribosomal protein L37a [Source:HGNC Symbol;Acc:HGNC:10348]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02921;K02921	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000197757	0	0	0	0	0.104	0	0	0	0	0	3	0	HOXC6	homeobox C6 [Source:HGNC Symbol;Acc:HGNC:5128]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0048706//embryonic skeletal system development"	Homeobox
ENSG00000197763	2.632	2.919	2.919	2.91	3.29	2.994	156	173	128	126	165	132	-	-	-	-	-	-	-	-	-	-
ENSG00000197766	1.113	1.931	1.579	2.152	2.465	1.224	22	38	22	31	40	16	CFD	complement factor D [Source:HGNC Symbol;Acc:HGNC:2771]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01334;K01334;K01334	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0007219//Notch signaling pathway;GO:0009617//response to bacterium;GO:0045087//innate immune response"	--
ENSG00000197768	0	0	0	0	0	0	0	0	0	0	0	0	STPG3	sperm-tail PG-rich repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:37285]	-	-	-	-	GO:0005856//cytoskeleton	-	-	--
ENSG00000197769	0.28	0.278	0.054	0.863	0.284	0.22	7	7	1	16	6	4	MAP1LC3C	microtubule associated protein 1 light chain 3 gamma [Source:HGNC Symbol;Acc:HGNC:13353]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Transport and catabolism;Signal transduction;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04216//Ferroptosis	K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0016236//macroautophagy;GO:0032527//protein exit from endoplasmic reticulum;GO:0035973//aggrephagy;GO:0097352//autophagosome maturation	--
ENSG00000197771	11.361	11.716	9.905	8.298	9.572	10.765	991	1027	638	536	705	684	MCMBP	minichromosome maintenance complex binding protein [Source:HGNC Symbol;Acc:HGNC:25782]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0042555//MCM complex	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0007049//cell cycle;GO:0007062//sister chromatid cohesion;GO:0051301//cell division	--
ENSG00000197774	1.024	1.495	1.196	1.313	2.31	1.886	116.8	134.46	122.98	108.44	150.28	166.12	EME2	essential meiotic structure-specific endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:27289]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10883	GO:0005634//nucleus;GO:0043596//nuclear replication fork;GO:0048476//Holliday junction resolvase complex;GO:1905347//endodeoxyribonuclease complex	GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0031573//mitotic intra-S DNA damage checkpoint signaling;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000197776	1.028	0.809	1.339	0.628	0.793	0.867	57	40	40	19	26	35	KLHDC1	kelch domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19836]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0016567//protein ubiquitination;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000197779	2.164	2.395	2.679	2.226	1.121	1.475	381	281	207	187	223	221	ZNF81	zinc finger protein 81 [Source:HGNC Symbol;Acc:HGNC:13156]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197780	15.718	16.18	15.934	16.913	12.503	13.964	388	404	301	289	254	245	TAF13	TATA-box binding protein associated factor 13 [Source:HGNC Symbol;Acc:HGNC:11546]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03127	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity	"GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0042789//mRNA transcription by RNA polymerase II;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter"	--
ENSG00000197782	6.187	4.493	4.831	4.762	5.53	5.029	468	394.76	254	258	267	283	ZNF780A	zinc finger protein 780A [Source:HGNC Symbol;Acc:HGNC:27603]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197785	12.426	12.397	14.33	14.598	13.652	12.277	640.41	641.24	546.21	553.22	585.65	460.11	ATAD3A	ATPase family AAA domain containing 3A [Source:HGNC Symbol;Acc:HGNC:25567]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042645//mitochondrial nucleoid	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042802//identical protein binding	GO:0001558//regulation of cell growth;GO:0007005//mitochondrion organization;GO:0043066//negative regulation of apoptotic process;GO:0140374//antiviral innate immune response	--
ENSG00000197786	0	0	0	0	0	0	0	0	0	0	0	0	OR5B17	olfactory receptor family 5 subfamily B member 17 [Source:HGNC Symbol;Acc:HGNC:15267]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197790	0	0	0	0	0	0	0	0	0	0	0	0	OR52M1	olfactory receptor family 52 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:15225]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197798	10.557	10.62	9.39	7.442	8.551	9.93	416	416	268	211	278	292	FAM118B	family with sequence similarity 118 member B [Source:HGNC Symbol;Acc:HGNC:26110]	-	-	-	-	GO:0005634//nucleus;GO:0015030//Cajal body	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0030576//Cajal body organization	--
ENSG00000197808	2.922	2.548	2.587	1.71	2.229	1.992	157	136	104	83	107.03	78	ZNF461	zinc finger protein 461 [Source:HGNC Symbol;Acc:HGNC:21629]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197816	0.662	0.482	0.693	0.332	0.436	0.441	97	71	75	36	54	47	CCDC180	coiled-coil domain containing 180 [Source:HGNC Symbol;Acc:HGNC:29303]	-	-	-	-	-	-	-	--
ENSG00000197818	6.628	6.725	7.661	6.487	6.985	6.47	851	864	725	614	756	603	SLC9A8	solute carrier family 9 member A8 [Source:HGNC Symbol;Acc:HGNC:20728]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0098656//anion transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000197822	4.073	3.697	4.364	3.721	4.251	3.792	336	326	273	241	294	240	OCLN	occludin [Source:HGNC Symbol;Acc:HGNC:8104]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06088;K06088;K06088;K06088;K06088	GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0031252//cell leading edge;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0070160//tight junction	GO:0005515//protein binding;GO:0019904//protein domain specific binding	GO:0001933//negative regulation of protein phosphorylation;GO:0010592//positive regulation of lamellipodium assembly;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010827//regulation of glucose transmembrane transport;GO:0031116//positive regulation of microtubule polymerization;GO:0035633//maintenance of blood-brain barrier;GO:0045216//cell-cell junction organization;GO:0046326//positive regulation of glucose import;GO:0065003//protein-containing complex assembly;GO:0070830//bicellular tight junction assembly;GO:0090303//positive regulation of wound healing;GO:0120193//tight junction organization;GO:1902463//protein localization to cell leading edge;GO:1905605//positive regulation of blood-brain barrier permeability	--
ENSG00000197826	0.062	0	0	0	0	0	1	0	0	0	0	0	CFAP299	cilia and flagella associated protein 299 [Source:HGNC Symbol;Acc:HGNC:28554]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000197837	0.05	0.05	0.034	0.136	0.364	0.035	2	2	1	4	5	1	H4-16	H4 histone 16 [Source:HGNC Symbol;Acc:HGNC:20510]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000197838	0	0	0	0	0	0	0	0	0	0	0	0	CYP2A13	cytochrome P450 family 2 subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:2608]	Metabolism;Human Diseases	Xenobiotics biodegradation and metabolism;Cancer: overview	ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts	K17685;K17685	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008389//coumarin 7-hydroxylase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0006082//organic acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009804//coumarin metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0046222//aflatoxin metabolic process	--
ENSG00000197841	10.206	8.697	10.771	8.878	10.044	10.946	416	301	247	194	296	213	ZNF181	zinc finger protein 181 [Source:HGNC Symbol;Acc:HGNC:12971]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197849	0	0	0	0	0	0	0	0	0	0	0	0	OR8G1	olfactory receptor family 8 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:8484]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197852	0.446	0.262	0.285	1.043	0.249	0.665	55	30	15	21	26	37	INKA2	inka box actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:28045]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity	GO:0043086//negative regulation of catalytic activity	--
ENSG00000197857	1.901	1.675	1.617	1.278	1.144	1.465	107	85	66	53	55	58	ZNF44	zinc finger protein 44 [Source:HGNC Symbol;Acc:HGNC:13110]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197858	82.669	90.298	89.523	113.135	103.164	86.257	3449	3807	2753	3479	3622	2646	GPAA1	glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05289;K05289	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042765//GPI-anchor transamidase complex	GO:0003923//GPI-anchor transamidase activity;GO:0005515//protein binding;GO:0015631//tubulin binding;GO:0034235//GPI anchor binding	GO:0006506//GPI anchor biosynthetic process;GO:0006508//proteolysis;GO:0006621//protein retention in ER lumen;GO:0016255//attachment of GPI anchor to protein;GO:0065003//protein-containing complex assembly	--
ENSG00000197859	3.566	4.4	3.21	2.862	3.193	2.411	281	349	185	172	213	141	ADAMTSL2	ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631]	-	-	-	-	GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0050436//microfibril binding	GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060481//lobar bronchus epithelium development	--
ENSG00000197860	1.92	2.062	2.038	1.566	1.367	0.997	217	195.86	104	106	115	82	SGTB	small glutamine rich tetratricopeptide repeat co-chaperone beta [Source:HGNC Symbol;Acc:HGNC:23567]	-	-	-	-	GO:0016020//membrane;GO:0072380//TRC complex	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000197863	4.168	2.698	2.845	3.036	3.278	3.242	151	112	96	85	118	106	ZNF790	zinc finger protein 790 [Source:HGNC Symbol;Acc:HGNC:33114]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197870	0	0	0	0	0	0	0	0	0	0	0	0	PRB3	proline rich protein BstNI subfamily 3 [Source:HGNC Symbol;Acc:HGNC:9339]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13911	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0008150//biological_process;GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000197872	0.544	0.236	0.21	0.236	0.381	0.29	21	23	15	16	18	16	CYRIA	CYFIP related Rac1 interactor A [Source:HGNC Symbol;Acc:HGNC:25373]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane	GO:0003674//molecular_function;GO:0031267//small GTPase binding	GO:0008150//biological_process;GO:0030833//regulation of actin filament polymerization;GO:0048583//regulation of response to stimulus	--
ENSG00000197879	32.661	32.095	32.423	41.901	43.606	35.902	3065	3090	2320	2970	3568	2513	MYO1C	myosin IC [Source:HGNC Symbol;Acc:HGNC:7597]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10356	GO:0001726//ruffle;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0016459//myosin complex;GO:0016461//unconventional myosin complex;GO:0016604//nuclear body;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031941//filamentous actin;GO:0031982//vesicle;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0045121//membrane raft;GO:0045335//phagocytic vesicle;GO:0060171//stereocilium membrane;GO:0070062//extracellular exosome;GO:0110016//B-WICH complex	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0031267//small GTPase binding;GO:0051015//actin filament binding	GO:0006338//chromatin remodeling;GO:0006612//protein targeting to membrane;GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0030050//vesicle transport along actin filament;GO:0030335//positive regulation of cell migration;GO:0035066//positive regulation of histone acetylation;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0051028//mRNA transport;GO:0071346//cellular response to interferon-gamma;GO:0090314//positive regulation of protein targeting to membrane;GO:1900078//positive regulation of cellular response to insulin stimulus;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:2000810//regulation of bicellular tight junction assembly	--
ENSG00000197885	11.483	8.701	10.189	6.987	7.831	8.375	467.02	390.52	308.72	232.95	312.48	300.32	NKIRAS1	NFKB inhibitor interacting Ras like 1 [Source:HGNC Symbol;Acc:HGNC:17899]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0032794//GTPase activating protein binding	GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0032484//Ral protein signal transduction;GO:0043129//surfactant homeostasis;GO:0048286//lung alveolus development	--
ENSG00000197887	0	0	0	0	0	0	0	0	0	0	0	0	OR1S2	olfactory receptor family 1 subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:15141]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197888	0	0	0	0	0	0	0	0	0	0	0	0	UGT2B17	UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000197889	0.333	0.422	0	0.286	0	0.194	4	6	0	3	0	2	MEIG1	meiosis/spermiogenesis associated 1 [Source:HGNC Symbol;Acc:HGNC:23429]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0007288//sperm axoneme assembly;GO:0030154//cell differentiation;GO:0034613//cellular protein localization;GO:1905198//manchette assembly	--
ENSG00000197891	0	0	0	0	0	0	0	0	0	0	0	0	SLC22A12	solute carrier family 22 member 12 [Source:HGNC Symbol;Acc:HGNC:17989]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0070062//extracellular exosome	GO:0015143//urate transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0030165//PDZ domain binding	GO:0006811//ion transport;GO:0009410//response to xenobiotic stimulus;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0019725//cellular homeostasis;GO:0032869//cellular response to insulin stimulus;GO:0046415//urate metabolic process;GO:0055085//transmembrane transport;GO:0097744//urate salt excretion	--
ENSG00000197892	16.252	14.208	15.735	12.759	13.94	14.765	2178	2128	1661	1286	1602	1445	KIF13B	kinesin family member 13B [Source:HGNC Symbol;Acc:HGNC:14405]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0030424//axon;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity;GO:0019901//protein kinase binding;GO:0071889//14-3-3 protein binding	GO:0006605//protein targeting;GO:0007018//microtubule-based movement;GO:0007165//signal transduction;GO:0042110//T cell activation;GO:0050770//regulation of axonogenesis	--
ENSG00000197893	0.036	0	0.036	0.024	0	0	4	0	3	2	0	0	NRAP	nebulin related anchoring protein [Source:HGNC Symbol;Acc:HGNC:7988]	-	-	-	-	GO:0005737//cytoplasm;GO:0005916//fascia adherens;GO:0005927//muscle tendon junction;GO:0030016//myofibril;GO:0030018//Z disc	GO:0003779//actin binding;GO:0005515//protein binding;GO:0017166//vinculin binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0051371//muscle alpha-actinin binding	GO:0008150//biological_process;GO:0071691//cardiac muscle thin filament assembly	--
ENSG00000197894	66.403	66.248	68.421	57.953	57.748	60.632	2877	2818	2249	2024	2270	1971	ADH5	"alcohol dehydrogenase 5 (class III), chi polypeptide [Source:HGNC Symbol;Acc:HGNC:253]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Global and overview maps;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko01200//Carbon metabolism;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K00121;K00121;K00121;K00121;K00121;K00121;K00121;K00121;K00121;K00121	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0005504//fatty acid binding;GO:0008270//zinc ion binding;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0018467//formaldehyde dehydrogenase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051903//S-(hydroxymethyl)glutathione dehydrogenase activity;GO:0106321//S-(hydroxymethyl)glutathione dehydrogenase NADP activity;GO:0106322//S-(hydroxymethyl)glutathione dehydrogenase NAD activity"	GO:0001523//retinoid metabolic process;GO:0003016//respiratory system process;GO:0006069//ethanol oxidation;GO:0006629//lipid metabolic process;GO:0010430//fatty acid omega-oxidation;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0022900//electron transport chain;GO:0032496//response to lipopolysaccharide;GO:0044281//small molecule metabolic process;GO:0045777//positive regulation of blood pressure;GO:0046294//formaldehyde catabolic process;GO:0051409//response to nitrosative stress;GO:0051775//response to redox state;GO:0071704//organic substance metabolic process	--
ENSG00000197901	0.574	0.722	0.644	1.897	1.314	1.184	23	32	21	62	49	38	SLC22A6	solute carrier family 22 member 6 [Source:HGNC Symbol;Acc:HGNC:10970]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008514//organic anion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0031404//chloride ion binding;GO:0042802//identical protein binding	GO:0006820//anion transport;GO:0014070//response to organic cyclic compound;GO:0015698//inorganic anion transport;GO:0015711//organic anion transport;GO:0015742//alpha-ketoglutarate transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0097254//renal tubular secretion;GO:0098656//anion transmembrane transport	--
ENSG00000197903	8.863	5.233	8.704	12.491	8.646	14.591	91	54	66	95	75	109	H2BC12	H2B clustered histone 12 [Source:HGNC Symbol;Acc:HGNC:13954]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000197905	5.274	4.995	5.945	6.696	7.488	6.883	182	153	147	160	216	174	TEAD4	TEA domain transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11717]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04390//Hippo signaling pathway;ko04392//Hippo signaling pathway - multiple species	K09448;K09448	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0032993//protein-DNA complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0001501//skeletal system development;GO:0001701//in utero embryonic development;GO:0001708//cell fate specification;GO:0001825//blastocyst formation;GO:0001830//trophectodermal cell fate commitment;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0007566//embryo implantation;GO:0035329//hippo signaling;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:1902459//positive regulation of stem cell population maintenance"	TEA
ENSG00000197912	21.553	23.898	25.358	24.032	27.397	26.368	1313	1479.01	1108	1120	1312	1068	SPG7	"SPG7 matrix AAA peptidase subunit, paraplegin [Source:HGNC Symbol;Acc:HGNC:11237]"	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005745//m-AAA complex;GO:0005757//mitochondrial permeability transition pore complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043229//intracellular organelle;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0004176//ATP-dependent peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0006508//proteolysis;GO:0007005//mitochondrion organization;GO:0007399//nervous system development;GO:0008089//anterograde axonal transport;GO:0016043//cellular component organization;GO:0034982//mitochondrial protein processing;GO:0046902//regulation of mitochondrial membrane permeability;GO:0065003//protein-containing complex assembly;GO:1902686//mitochondrial outer membrane permeabilization involved in programmed cell death	--
ENSG00000197915	0	0	0	0	0.006	0	0	0	0	0	1	0	HRNR	hornerin [Source:HGNC Symbol;Acc:HGNC:20846]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0036457//keratohyalin granule;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	GO:0031424//keratinization;GO:0043163//cell envelope organization;GO:0061436//establishment of skin barrier	--
ENSG00000197919	0	0	0	0	0	0	0	0	0	0	0	0	IFNA1	interferon alpha 1 [Source:HGNC Symbol;Acc:HGNC:5417]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0051707//response to other organism;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000197921	0.036	0	0	0.049	0	0	1	0	0	1	0	0	HES5	hes family bHLH transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:19764]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: specific types;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05224//Breast cancer;ko04330//Notch signaling pathway	K06055;K06055;K06055;K06055	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway;GO:0007224//smoothened signaling pathway;GO:0007399//nervous system development;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0009952//anterior/posterior pattern specification;GO:0014003//oligodendrocyte development;GO:0021537//telencephalon development;GO:0021781//glial cell fate commitment;GO:0021861//forebrain radial glial cell differentiation;GO:0021915//neural tube development;GO:0022010//central nervous system myelination;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0031641//regulation of myelination;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043010//camera-type eye development;GO:0045595//regulation of cell differentiation;GO:0045608//negative regulation of inner ear auditory receptor cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048469//cell maturation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048708//astrocyte differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0050678//regulation of epithelial cell proliferation;GO:0050767//regulation of neurogenesis;GO:0051216//cartilage development;GO:0060122//inner ear receptor cell stereocilium organization;GO:0065003//protein-containing complex assembly;GO:0072049//comma-shaped body morphogenesis;GO:0072050//S-shaped body morphogenesis;GO:0072086//specification of loop of Henle identity;GO:0072282//metanephric nephron tubule morphogenesis;GO:0090162//establishment of epithelial cell polarity;GO:0097150//neuronal stem cell population maintenance;GO:2000737//negative regulation of stem cell differentiation;GO:2000974//negative regulation of pro-B cell differentiation;GO:2000978//negative regulation of forebrain neuron differentiation;GO:2000981//negative regulation of inner ear receptor cell differentiation"	bHLH
ENSG00000197928	2.329	2.433	1.376	2.136	1.635	1.565	44	42	22	28	28	21	ZNF677	zinc finger protein 677 [Source:HGNC Symbol;Acc:HGNC:28730]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197930	15.837	14.348	13.586	10.787	13.686	12.669	1319	1201	804	664	900	720	ERO1A	endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280]	Human Diseases;Genetic Information Processing;Human Diseases	"Cardiovascular disease;Folding, sorting and degradation;Infectious disease: bacterial"	ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05110//Vibrio cholerae infection	K10950;K10950;K10950	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0015036//disulfide oxidoreductase activity;GO:0016491//oxidoreductase activity;GO:0016972//thiol oxidase activity;GO:0071949//FAD binding	GO:0006457//protein folding;GO:0006464//cellular protein modification process;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0009266//response to temperature stimulus;GO:0010260//animal organ senescence;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0022417//protein maturation by protein folding;GO:0030070//insulin processing;GO:0030198//extracellular matrix organization;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034975//protein folding in endoplasmic reticulum;GO:0034976//response to endoplasmic reticulum stress;GO:0045454//cell redox homeostasis;GO:0050873//brown fat cell differentiation;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051209//release of sequestered calcium ion into cytosol;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071456//cellular response to hypoxia	--
ENSG00000197933	1.704	1.586	1.728	1.209	1.336	0.989	65	56	49	26	42	29	ZNF823	zinc finger protein 823 [Source:HGNC Symbol;Acc:HGNC:30936]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197935	0.866	1.017	1.056	0.608	0.779	0.81	50	59	45	26	38	34	ZNF311	zinc finger protein 311 [Source:HGNC Symbol;Acc:HGNC:13847]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197937	2.778	2.356	1.726	1.566	2.547	1.882	349	222	141	128	185	140	ZNF347	zinc finger protein 347 [Source:HGNC Symbol;Acc:HGNC:16447]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197938	0	0	0	0	0	0	0	0	0	0	0	0	OR5H2	olfactory receptor family 5 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:14752]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000197943	0.434	0.482	0.63	0.481	0.362	0.382	78	87	70	64	55	50	PLCG2	phospholipase C gamma 2 [Source:HGNC Symbol;Acc:HGNC:9066]	Metabolism;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Metabolism;Human Diseases;Environmental Information Processing;Human Diseases	Global and overview maps;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Signal transduction;Cancer: overview;Immune system;Cancer: specific types;Immune system;Immune system;Development and regeneration;Immune system;Endocrine system;Nervous system;Endocrine system;Signal transduction;Immune system;Immune system;Endocrine and metabolic disease;Sensory system;Signal transduction;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Carbohydrate metabolism;Infectious disease: bacterial;Signal transduction;Infectious disease: bacterial	"ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04064//NF-kappa B signaling pathway;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04625//C-type lectin receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05223//Non-small cell lung cancer;ko00562//Inositol phosphate metabolism;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway;ko05110//Vibrio cholerae infection"	K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859;K05859	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0032587//ruffle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0097708//intracellular vesicle	GO:0001784//phosphotyrosine residue binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0097110//scaffold protein binding;GO:0140031//phosphorylation-dependent protein binding;GO:1990782//protein tyrosine kinase binding	"GO:0001775//cell activation;GO:0001878//response to yeast;GO:0002092//positive regulation of receptor internalization;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0002281//macrophage activation involved in immune response;GO:0002316//follicular B cell differentiation;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0009395//phospholipid catabolic process;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010634//positive regulation of epithelial cell migration;GO:0016042//lipid catabolic process;GO:0016055//Wnt signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0019722//calcium-mediated signaling;GO:0030168//platelet activation;GO:0030183//B cell differentiation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032237//activation of store-operated calcium channel activity;GO:0032481//positive regulation of type I interferon production;GO:0032496//response to lipopolysaccharide;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032743//positive regulation of interleukin-2 production;GO:0032747//positive regulation of interleukin-23 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032959//inositol trisphosphate biosynthetic process;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043069//negative regulation of programmed cell death;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0048678//response to axon injury;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0060907//positive regulation of macrophage cytokine production;GO:0061760//antifungal innate immune response;GO:0070884//regulation of calcineurin-NFAT signaling cascade;GO:0071277//cellular response to calcium ion;GO:0071396//cellular response to lipid;GO:0150078//positive regulation of neuroinflammatory response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1990858//cellular response to lectin"	--
ENSG00000197948	3.405	3.818	5.514	3.062	5.109	3.39	170.13	200.17	157.47	136.19	163.5	141.69	FCHSD1	FCH and double SH3 domains 1 [Source:HGNC Symbol;Acc:HGNC:25463]	-	-	-	-	GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0031594//neuromuscular junction;GO:0032437//cuticular plate;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0007274//neuromuscular synaptic transmission;GO:0030833//regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0061024//membrane organization	--
ENSG00000197951	2.076	2.291	2.129	2.806	2.335	2.342	195	209	149	178	172	148	ZNF71	zinc finger protein 71 [Source:HGNC Symbol;Acc:HGNC:13141]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000197953	0	0	0	0	0	0	0	0	0	0	0	0	AADACL2	arylacetamide deacetylase like 2 [Source:HGNC Symbol;Acc:HGNC:24427]	-	-	-	-	GO:0005576//extracellular region;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	-	--
ENSG00000197956	137.633	129.152	136.097	99.885	84.382	114.791	1245	1180	912	670	645	758	S100A6	S100 calcium binding protein A6 [Source:HGNC Symbol;Acc:HGNC:10496]	-	-	-	-	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005523//tropomyosin binding;GO:0008270//zinc ion binding;GO:0015075//ion transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0044548//S100 protein binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding	GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0034220//ion transmembrane transport;GO:0048146//positive regulation of fibroblast proliferation	--
ENSG00000197958	529.066	600.241	539.515	540.297	497.112	452.579	6957	7934	5240	5263	5523	4330	RPL12	ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02870;K02870	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0070180//large ribosomal subunit rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000197959	0.61	0.765	0.975	0.438	0.528	0.418	80	75	51	24	47	24	DNM3	dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]	Cellular Processes;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Transport and catabolism;Signal transduction;Infectious disease: bacterial;Nervous system;Excretory system	ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko04721//Synaptic vesicle cycle;ko04961//Endocrine and other factor-regulated calcium reabsorption	K01528;K01528;K01528;K01528;K01528	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030424//axon;GO:0043083//synaptic cleft;GO:0043197//dendritic spine;GO:0044327//dendritic spine head;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0061828//apical tubulobulbar complex;GO:0061829//basal tubulobulbar complex;GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0098844//postsynaptic endocytic zone membrane;GO:0098978//glutamatergic synapse	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0016787//hydrolase activity;GO:0031798//type 1 metabotropic glutamate receptor binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0050998//nitric-oxide synthase binding;GO:0099186//structural constituent of postsynapse	GO:0006897//endocytosis;GO:0007416//synapse assembly;GO:0031623//receptor internalization;GO:0046847//filopodium assembly;GO:0048488//synaptic vesicle endocytosis;GO:0051491//positive regulation of filopodium assembly;GO:0061001//regulation of dendritic spine morphogenesis;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:0099173//postsynapse organization;GO:1903423//positive regulation of synaptic vesicle recycling	--
ENSG00000197961	0.731	0.457	0.464	0.438	0.539	0.5	106	67	51	47	66	53	ZNF121	zinc finger protein 121 [Source:HGNC Symbol;Acc:HGNC:12904]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000197965	48.067	46.722	42.926	47.634	47.813	41.673	3000	2987	1933	2035	2533	1835	MPZL1	myelin protein zero like 1 [Source:HGNC Symbol;Acc:HGNC:7226]	Environmental Information Processing	Signaling molecules and interaction	ko04514//Cell adhesion molecules	K06770	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling	--
ENSG00000197969	4.43	1.933	1.694	1.438	1.913	2.321	1160	537	343	281	443	469	VPS13A	vacuolar protein sorting 13 homolog A [Source:HGNC Symbol;Acc:HGNC:1908]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031045//dense core granule;GO:0031410//cytoplasmic vesicle;GO:0031966//mitochondrial membrane;GO:0097225//sperm midpiece;GO:0098992//neuronal dense core vesicle;GO:0099013//neuronal dense core vesicle lumen	GO:0005515//protein binding	GO:0006623//protein targeting to vacuole;GO:0006895//Golgi to endosome transport;GO:0006914//autophagy;GO:0007399//nervous system development;GO:0007626//locomotory behavior;GO:0008104//protein localization;GO:0015031//protein transport;GO:0030317//flagellated sperm motility;GO:0030382//sperm mitochondrion organization;GO:0035176//social behavior;GO:0045053//protein retention in Golgi apparatus;GO:1905146//lysosomal protein catabolic process	--
ENSG00000197971	36.101	26.498	31.813	36.166	38.155	32.498	2969	2406	2098	2148	2204	2109	MBP	myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0033269//internode region of axon;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0043218//compact myelin;GO:0045202//synapse;GO:0071944//cell periphery	GO:0002020//protease binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0019911//structural constituent of myelin sheath	GO:0000165//MAPK cascade;GO:0006955//immune response;GO:0007268//chemical synaptic transmission;GO:0007417//central nervous system development;GO:0007568//aging;GO:0007605//sensory perception of sound;GO:0008366//axon ensheathment;GO:0009636//response to toxic substance;GO:0021762//substantia nigra development;GO:0032570//response to progesterone;GO:0032755//positive regulation of interleukin-6 production;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034612//response to tumor necrosis factor;GO:0035633//maintenance of blood-brain barrier;GO:0042552//myelination;GO:0046689//response to mercury ion;GO:0050771//negative regulation of axonogenesis;GO:0061024//membrane organization;GO:0070542//response to fatty acid;GO:1904685//positive regulation of metalloendopeptidase activity;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production	--
ENSG00000197976	9.236	9.295	8.694	9.553	10.223	8.609	593	598	406	460	550	405	AKAP17A	A-kinase anchoring protein 17A [Source:HGNC Symbol;Acc:HGNC:18783]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0051018//protein kinase A binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0007165//signal transduction;GO:0008380//RNA splicing;GO:0042113//B cell activation;GO:0043484//regulation of RNA splicing"	--
ENSG00000197977	0.351	0.313	0.458	0.555	0.372	0.332	29	26	28	34	26	20	ELOVL2	ELOVL fatty acid elongase 2 [Source:HGNC Symbol;Acc:HGNC:14416]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10205;K10205;K10205;K10205	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0005515//protein binding;GO:0009922//fatty acid elongase activity;GO:0016740//transferase activity;GO:0016747//acyltransferase activity, transferring groups other than amino-acyl groups;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity"	"GO:0000038//very long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process"	--
ENSG00000197978	0.789	0.599	0.612	0.608	0.836	0.829	70.46	53.79	40.34	40.24	63.06	53.85	GOLGA6L9	golgin A6 family like 9 [Source:HGNC Symbol;Acc:HGNC:37229]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000197980	0.301	0.223	0.375	0.067	0.147	0.136	9	9	4	2	5	2	LEKR1	"leucine, glutamate and lysine rich 1 [Source:HGNC Symbol;Acc:HGNC:33765]"	-	-	-	-	-	-	-	--
ENSG00000197982	47.694	49.514	50.604	50.902	48.463	48.933	1248.62	1311.47	978.42	988.14	1075.54	939.68	C1orf122	chromosome 1 open reading frame 122 [Source:HGNC Symbol;Acc:HGNC:24789]	-	-	-	-	-	-	-	--
ENSG00000197991	0	0	0	0	0	0	0	0	0	0	0	0	PCDH20	novel protein	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000197992	0	0	0	0	0	0	0	0	0	0	0	0	CLEC9A	C-type lectin domain containing 9A [Source:HGNC Symbol;Acc:HGNC:26705]	-	-	-	-	GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding	GO:0001819//positive regulation of cytokine production;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis	--
ENSG00000197993	0	0	0	0	0	0	0	0	0	0	0	0	KEL	Kell metallo-endopeptidase (Kell blood group) [Source:HGNC Symbol;Acc:HGNC:6308]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0006874//cellular calcium ion homeostasis;GO:0008361//regulation of cell size;GO:0010961//cellular magnesium ion homeostasis;GO:0016485//protein processing;GO:0031133//regulation of axon diameter;GO:0042310//vasoconstriction;GO:0042552//myelination;GO:0048741//skeletal muscle fiber development;GO:1901380//negative regulation of potassium ion transmembrane transport	--
ENSG00000198000	5.855	3.684	3.332	2.874	5.521	3.469	358	296	168	156	223	143	NOL8	nucleolar protein 8 [Source:HGNC Symbol;Acc:HGNC:23387]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006364//rRNA processing;GO:1902570//protein localization to nucleolus	--
ENSG00000198001	5.519	4.757	5.002	4.737	5.11	4.354	316	310	234	217	240	192	IRAK4	interleukin 1 receptor associated kinase 4 [Source:HGNC Symbol;Acc:HGNC:17967]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Nervous system;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04722//Neurotrophin signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05133//Pertussis	K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733;K04733	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0106310//protein serine kinase activity	GO:0002224//toll-like receptor signaling pathway;GO:0002376//immune system process;GO:0002446//neutrophil mediated immunity;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007254//JNK cascade;GO:0016310//phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035556//intracellular signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0070498//interleukin-1-mediated signaling pathway;GO:1990266//neutrophil migration	--
ENSG00000198003	1	1.452	0.953	1.314	1.21	1.479	43	62	31	41	45	48	ODAD3	outer dynein arm docking complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28303]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0007368//determination of left/right symmetry;GO:0030030//cell projection organization;GO:0036158//outer dynein arm assembly;GO:1902017//regulation of cilium assembly	--
ENSG00000198010	0.089	0.024	0.032	0.199	0.023	0.013	17	5	5	5	4	2	DLGAP2	DLG associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2906]	-	-	-	-	GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0098978//glutamatergic synapse;GO:0099572//postsynaptic specialization	GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0007270//neuron-neuron synaptic transmission;GO:0023052//signaling;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000198015	23.542	20.626	19.427	14.519	18.173	19.316	814	664	472	383	494	508	MRPL42	mitochondrial ribosomal protein L42 [Source:HGNC Symbol;Acc:HGNC:14493]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000198018	3.753	3.249	3.23	2.477	2.61	2.504	665.39	579	423	325.31	391	323	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7 [Source:HGNC Symbol;Acc:HGNC:19745]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0003924//GTPase activity;GO:0004382//guanosine-diphosphatase activity;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0043273//CTPase activity;GO:0045134//uridine-diphosphatase activity;GO:0046872//metal ion binding	GO:0006254//CTP catabolic process;GO:0006256//UDP catabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0046039//GTP metabolic process;GO:0046052//UTP catabolic process;GO:0050776//regulation of immune response;GO:0072539//T-helper 17 cell differentiation	--
ENSG00000198019	0	0	0	0	0.097	0	0	0	0	0	3	0	FCGR1B	Fc fragment of IgG receptor Ib [Source:HGNC Symbol;Acc:HGNC:3614]	Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Transport and catabolism;Immune disease;Immune system;Infectious disease: bacterial;Immune system;Infectious disease: parasitic;Development and regeneration;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation;ko05221//Acute myeloid leukemia	K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498;K06498	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031901//early endosome membrane	GO:0004888//transmembrane signaling receptor activity;GO:0019763//immunoglobulin receptor activity;GO:0019864//IgG binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0038093//Fc receptor signaling pathway;GO:0050776//regulation of immune response	--
ENSG00000198021	0	0	0	0	0	0	0	0	0	0	0	0	SPANXA1	"sperm protein associated with the nucleus, X-linked, family member A1 [Source:HGNC Symbol;Acc:HGNC:11218]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007283//spermatogenesis	--
ENSG00000198026	5.001	5.212	5.672	4.442	5.202	5.698	462	484	387	304	406	383	ZNF335	zinc finger protein 335 [Source:HGNC Symbol;Acc:HGNC:15807]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0001701//in utero embryonic development;GO:0002052//positive regulation of neuroblast proliferation;GO:0007420//brain development;GO:0010468//regulation of gene expression;GO:0021895//cerebral cortex neuron differentiation;GO:0040029//regulation of gene expression, epigenetic;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048812//neuron projection morphogenesis;GO:0048854//brain morphogenesis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0050767//regulation of neurogenesis;GO:0050769//positive regulation of neurogenesis;GO:0051569//regulation of histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation"	zf-C2H2
ENSG00000198028	0.017	0	0	0	0	0	1	0	0	0	0	0	ZNF560	zinc finger protein 560 [Source:HGNC Symbol;Acc:HGNC:26484]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198033	0	0	0	0	0	0	0	0	0	0	0	0	TUBA3C	tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process	--
ENSG00000198034	428.342	456.673	408.447	445.756	405.609	356.117	13096	14033.96	9223	10095	10477	7922	RPS4X	ribosomal protein S4 X-linked [Source:HGNC Symbol;Acc:HGNC:10424]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02987;K02987	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005844//polysome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0070062//extracellular exosome;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0008284//positive regulation of cell population proliferation;GO:0010467//gene expression;GO:0045727//positive regulation of translation	--
ENSG00000198039	1.147	0.83	0.847	0.493	0.772	0.674	89	64	48	28	50	38	ZNF273	zinc finger protein 273 [Source:HGNC Symbol;Acc:HGNC:13067]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198040	7.597	5.796	6.122	5.53	6.278	5.378	659	536	328	302	441	351	ZNF84	zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198042	3.001	2.616	2.627	1.647	1.515	1.75	208.53	175.11	108.67	90.12	94.57	94.07	MAK16	MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703]	-	-	-	-	"GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0043231//intracellular membrane-bounded organelle"	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA	--
ENSG00000198046	2.871	2.153	2.669	2.503	2.036	2.979	233	183	128	142	138	130	ZNF667	zinc finger protein 667 [Source:HGNC Symbol;Acc:HGNC:28854]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198049	0.01	0	0	0	0	0	1	0	0	0	0	0	AVPR1B	arginine vasopressin receptor 1B [Source:HGNC Symbol;Acc:HGNC:896]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Circulatory system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04072//Phospholipase D signaling pathway;ko04270//Vascular smooth muscle contraction	K04227;K04227;K04227;K04227	GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0043679//axon terminus	GO:0004930//G protein-coupled receptor activity;GO:0005000//vasopressin receptor activity;GO:0005080//protein kinase C binding;GO:0017046//peptide hormone binding;GO:0042277//peptide binding;GO:0042802//identical protein binding	GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008217//regulation of blood pressure;GO:0010259//multicellular organism aging;GO:0014049//positive regulation of glutamate secretion;GO:0032430//positive regulation of phospholipase A2 activity;GO:0032849//positive regulation of cellular pH reduction;GO:0042127//regulation of cell population proliferation;GO:0042538//hyperosmotic salinity response;GO:0043410//positive regulation of MAPK cascade;GO:0045907//positive regulation of vasoconstriction;GO:0046718//viral entry into host cell;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0150104//transport across blood-brain barrier	--
ENSG00000198053	23.519	24.335	20.015	18.874	22.265	20.761	1943.81	2021.88	1225	1152	1558.87	1254	SIRPA	signal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662]	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K06551	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0017124//SH3 domain binding;GO:0019903//protein phosphatase binding;GO:0030695//GTPase regulator activity;GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0098632//cell-cell adhesion mediator activity;GO:1990405//protein antigen binding;GO:1990782//protein tyrosine kinase binding	GO:0001933//negative regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0010468//regulation of gene expression;GO:0016477//cell migration;GO:0032649//regulation of interferon-gamma production;GO:0032651//regulation of interleukin-1 beta production;GO:0032675//regulation of interleukin-6 production;GO:0032680//regulation of tumor necrosis factor production;GO:0032688//negative regulation of interferon-beta production;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034113//heterotypic cell-cell adhesion;GO:0035696//monocyte extravasation;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0046329//negative regulation of JNK cascade;GO:0050728//negative regulation of inflammatory response;GO:0050765//negative regulation of phagocytosis;GO:0050766//positive regulation of phagocytosis;GO:0050790//regulation of catalytic activity;GO:0050870//positive regulation of T cell activation;GO:0070301//cellular response to hydrogen peroxide;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071349//cellular response to interleukin-12;GO:0071641//negative regulation of macrophage inflammatory protein 1 alpha production;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0098609//cell-cell adhesion;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:1903720//negative regulation of I-kappaB phosphorylation	--
ENSG00000198055	7.422	7.536	7.883	10.547	9.489	7.539	372	356	280	314	337	261	GRK6	G protein-coupled receptor kinase 6 [Source:HGNC Symbol;Acc:HGNC:4545]	Cellular Processes;Organismal Systems;Human Diseases	Transport and catabolism;Immune system;Substance dependence	ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko05032//Morphine addiction	K08291;K08291;K08291	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0047696//beta-adrenergic receptor kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0009966//regulation of signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation	--
ENSG00000198056	0.862	1.615	1.876	1.294	1.783	2.143	28	50	44	29	46	51	PRIM1	DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369]	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02684	GO:0005654//nucleoplasm;GO:0005658//alpha DNA polymerase:primase complex;GO:0016020//membrane	GO:0000287//magnesium ion binding;GO:0003896//DNA primase activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0032553//ribonucleotide binding;GO:0046872//metal ion binding	"GO:0006260//DNA replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006270//DNA replication initiation"	--
ENSG00000198060	14.554	15.458	14.247	12.596	13.095	15.306	1184	1264	856	759	900	906	MARCHF5	membrane associated ring-CH-type finger 5 [Source:HGNC Symbol;Acc:HGNC:26025]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0051020//GTPase binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0070585//protein localization to mitochondrion;GO:0090140//regulation of mitochondrial fission;GO:0090141//positive regulation of mitochondrial fission;GO:0090344//negative regulation of cell aging	--
ENSG00000198062	0	0	0	0	0	0	0	0	0	0	0	0	POTEH	POTE ankyrin domain family member H [Source:HGNC Symbol;Acc:HGNC:133]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000198064	1.451	0.6	1.633	1.544	1.006	1.902	58.03	44.41	53.37	37.64	43.45	40.12	NPIPB13	"nuclear pore complex interacting protein family, member B13 [Source:HGNC Symbol;Acc:HGNC:41989]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000198074	0	0	0	0	0	0	0	0	0	0	0	0	AKR1B10	aldo-keto reductase family 1 member B10 [Source:HGNC Symbol;Acc:HGNC:382]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko00040//Pentose and glucuronate interconversions;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00790//Folate biosynthesis	K00011;K00011;K00011;K00011;K00011;K00011	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005829//cytosol	GO:0001758//retinal dehydrogenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0005515//protein binding;GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0016491//oxidoreductase activity;GO:0045550//geranylgeranyl reductase activity;GO:0047655//allyl-alcohol dehydrogenase activity;GO:0047718//indanol dehydrogenase activity;GO:0052650//NADP-retinol dehydrogenase activity	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0016488//farnesol catabolic process;GO:0042572//retinol metabolic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0110095//cellular detoxification of aldehyde	--
ENSG00000198075	9.93	9.474	8.447	8.132	6.903	5.942	382	398	258	236.95	251	175.95	SULT1C4	sulfotransferase family 1C member 4 [Source:HGNC Symbol;Acc:HGNC:11457]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0006068//ethanol catabolic process;GO:0006805//xenobiotic metabolic process;GO:0009812//flavonoid metabolic process;GO:0044598//doxorubicin metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation	--
ENSG00000198077	0	0	0	0	0	0	0	0	0	0	0	0	CYP2A7	cytochrome P450 family 2 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:2611]	Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00232//Caffeine metabolism	K17683;K17683;K17683;K17683;K17683;K17683;K17683;K17683	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	GO:0006082//organic acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009804//coumarin metabolic process;GO:0019373//epoxygenase P450 pathway	--
ENSG00000198081	7.677	5.713	6.366	6.25	4.77	5.838	358	335	258	250	251	231	ZBTB14	zinc finger and BTB domain containing 14 [Source:HGNC Symbol;Acc:HGNC:12860]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016235//aggresome	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001822//kidney development;GO:0003170//heart valve development;GO:0003279//cardiac septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060976//coronary vasculature development"	ZBTB
ENSG00000198083	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-9	keratin associated protein 9-9 [Source:HGNC Symbol;Acc:HGNC:16773]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000198087	7.821	5.787	5.753	4.269	4.566	5.007	878	653	477	355	433	409	CD2AP	CD2 associated protein [Source:HGNC Symbol;Acc:HGNC:14258]	Human Diseases	Infectious disease: bacterial	ko05100//Bacterial invasion of epithelial cells	K13738	GO:0001650//fibrillar center;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0015629//actin cytoskeleton;GO:0030054//cell junction;GO:0030139//endocytic vesicle;GO:0030424//axon;GO:0030425//dendrite;GO:0031252//cell leading edge;GO:0031941//filamentous actin;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005172//vascular endothelial growth factor receptor binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding;GO:0017124//SH3 domain binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding;GO:0045296//cadherin binding	"GO:0006930//substrate-dependent cell migration, cell extension;GO:0007015//actin filament organization;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0016050//vesicle organization;GO:0016477//cell migration;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0048259//regulation of receptor-mediated endocytosis;GO:0050714//positive regulation of protein secretion;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0051301//cell division;GO:0065003//protein-containing complex assembly;GO:0098609//cell-cell adhesion;GO:1900182//positive regulation of protein localization to nucleus;GO:2000249//regulation of actin cytoskeleton reorganization"	--
ENSG00000198088	2.049	2.104	1.53	1.266	1.069	1.325	41	39	25	23	19	16	NUP62CL	nucleoporin 62 C-terminal like [Source:HGNC Symbol;Acc:HGNC:25960]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14306;K14306	GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0044613//nuclear pore central transport channel	GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport	--
ENSG00000198089	2.152	2.566	2.574	2.456	2.676	2.743	183	214	160	155.54	191	166	SFI1	SFI1 centrin binding protein [Source:HGNC Symbol;Acc:HGNC:29064]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019902//phosphatase binding	-	--
ENSG00000198090	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-6	keratin associated protein 4-6 [Source:HGNC Symbol;Acc:HGNC:18909]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000198092	0	0	0	0	0	0	0	0	0	0	0	0	TMPRSS11F	transmembrane serine protease 11F [Source:HGNC Symbol;Acc:HGNC:29994]	-	-	-	-	GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0033561//regulation of water loss via skin	--
ENSG00000198093	5.698	5.937	5.583	4.615	3.927	4.629	371	358	226	178	216	223	ZNF649	zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005615//extracellular space;GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198099	0	0	0	0	0	0	0	0	0	0	0	0	ADH4	"alcohol dehydrogenase 4 (class II), pi polypeptide [Source:HGNC Symbol;Acc:HGNC:252]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13980;K13980;K13980;K13980;K13980;K13980;K13980;K13980;K13980	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0003960//NADPH:quinone reductase activity;GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004745//NAD-retinol dehydrogenase activity;GO:0005503//all-trans retinal binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0019115//benzaldehyde dehydrogenase [NAD(P)+] activity;GO:0019841//retinol binding;GO:0035276//ethanol binding;GO:0046872//metal ion binding;GO:0051287//NAD binding;GO:0051903//S-(hydroxymethyl)glutathione dehydrogenase activity"	GO:0001523//retinoid metabolic process;GO:0006066//alcohol metabolic process;GO:0006067//ethanol metabolic process;GO:0006069//ethanol oxidation;GO:0006081//cellular aldehyde metabolic process;GO:0006629//lipid metabolic process;GO:0010430//fatty acid omega-oxidation;GO:0042572//retinol metabolic process;GO:0046164//alcohol catabolic process;GO:0046294//formaldehyde catabolic process;GO:1901661//quinone metabolic process	--
ENSG00000198104	0	0	0	0	0	0	0	0	0	0	0	0	OR2T6	olfactory receptor family 2 subfamily T member 6 [Source:HGNC Symbol;Acc:HGNC:15018]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198105	2.007	2.115	2.636	1.242	1.65	2.032	187	196	89	82	112	108	ZNF248	zinc finger protein 248 [Source:HGNC Symbol;Acc:HGNC:13041]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198108	3.05	2.86	3.097	2.683	1.983	2.989	244	230	183	159	134	174	CHSY3	chondroitin sulfate synthase 3 [Source:HGNC Symbol;Acc:HGNC:24293]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K13499;K13499	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane	GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	GO:0030206//chondroitin sulfate biosynthetic process	--
ENSG00000198113	5.71	6.014	7.199	7.911	6.964	7.022	494	523	460	507	509	442	TOR4A	torsin family 4 member A [Source:HGNC Symbol;Acc:HGNC:25981]	-	-	-	-	GO:0005576//extracellular region;GO:0005635//nuclear envelope;GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031093//platelet alpha granule lumen	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000198121	1.507	1.268	1.644	1.674	1.453	1.564	80	89	58	72	65	61	LPAR1	lysophosphatidic acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:3166]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes	Cancer: overview;Signal transduction;Signaling molecules and interaction;Infectious disease: bacterial;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko05130//Pathogenic Escherichia coli infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04540//Gap junction	K04289;K04289;K04289;K04289;K04289;K04289;K04289;K04289	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft	GO:0001965//G-protein alpha-subunit binding;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0030165//PDZ domain binding;GO:0035727//lysophosphatidic acid binding;GO:0070915//lysophosphatidic acid receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007420//brain development;GO:0008360//regulation of cell shape;GO:0010942//positive regulation of cell death;GO:0010977//negative regulation of neuron projection development;GO:0014003//oligodendrocyte development;GO:0019222//regulation of metabolic process;GO:0021549//cerebellum development;GO:0021554//optic nerve development;GO:0022008//neurogenesis;GO:0022038//corpus callosum development;GO:0032060//bleb assembly;GO:0035025//positive regulation of Rho protein signal transduction;GO:0042552//myelination;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0060326//cell chemotaxis;GO:0060999//positive regulation of dendritic spine development;GO:0071453//cellular response to oxygen levels;GO:0071673//positive regulation of smooth muscle cell chemotaxis;GO:1904566//cellular response to 1-oleoyl-sn-glycerol 3-phosphate	--
ENSG00000198125	0	0.046	0.063	0	0.055	0	0	1	1	0	1	0	MB	myoglobin [Source:HGNC Symbol;Acc:HGNC:6915]	-	-	-	-	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0001666//response to hypoxia;GO:0007507//heart development;GO:0015671//oxygen transport;GO:0043353//enucleate erythrocyte differentiation;GO:0050873//brown fat cell differentiation	--
ENSG00000198128	0	0	0	0	0	0	0	0	0	0	0	0	OR2L3	olfactory receptor family 2 subfamily L member 3 [Source:HGNC Symbol;Acc:HGNC:15009]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198129	0	0	0	0	0	0	0	0	0	0	0	0	DEFB107B	defensin beta 107B [Source:HGNC Symbol;Acc:HGNC:31918]	-	-	-	-	GO:0005576//extracellular region	GO:0008289//lipid binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000198130	8.09	5.42	8.309	7.076	7.255	6.239	300	252	236	234	241	222	HIBCH	3-hydroxyisobutyryl-CoA hydrolase [Source:HGNC Symbol;Acc:HGNC:4908]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism;ko00410//beta-Alanine metabolism"	K05605;K05605;K05605;K05605;K05605	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003860//3-hydroxyisobutyryl-CoA hydrolase activity;GO:0016787//hydrolase activity	GO:0006574//valine catabolic process;GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000198131	17.076	15.215	11.463	12.227	14.031	11.565	393.73	395.72	241.58	210	274	204.5	ZNF544	zinc finger protein 544 [Source:HGNC Symbol;Acc:HGNC:16759]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198133	10.792	12.043	10.987	7.497	9.642	8.193	925	1024	698	473	698	509	TMEM229B	transmembrane protein 229B [Source:HGNC Symbol;Acc:HGNC:20130]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0009617//response to bacterium	--
ENSG00000198142	2.97	2.892	3.287	2.602	3.046	3.251	285	279	233	185	247	227	SOWAHC	sosondowah ankyrin repeat domain family member C [Source:HGNC Symbol;Acc:HGNC:26149]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000198146	15.459	10.679	11.315	9.31	11.189	12.536	1744	1211	885	778	972	1029	ZNF770	zinc finger protein 770 [Source:HGNC Symbol;Acc:HGNC:26061]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000198156	0.039	0.28	0.219	0.264	0.103	0.087	1.53	10.48	6.34	7.9	3.43	1.74	NPIPB6	nuclear pore complex interacting protein family member B6 [Source:HGNC Symbol;Acc:HGNC:37454]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000198157	2.447	1.747	1.619	0.479	1.298	2.331	42	40	32	10	26	33	HMGN5	high mobility group nucleosome binding domain 5 [Source:HGNC Symbol;Acc:HGNC:8013]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0031492//nucleosomal DNA binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000198160	10.783	7.831	7.581	5.637	6.983	9.239	965	704	503	405	521	606	MIER1	MIER1 transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29657]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0017053//transcription repressor complex;GO:0032991//protein-containing complex	GO:0003714//transcription corepressor activity;GO:0004407//histone deacetylase activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling"	MYB
ENSG00000198162	20.998	14.194	15.519	12.261	15.395	14.842	3138	2285	1748	1507	1946	1921	MAN1A2	mannosidase alpha class 1A member 2 [Source:HGNC Symbol;Acc:HGNC:6822]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K01230;K01230;K01230;K01230	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008152//metabolic process;GO:0009100//glycoprotein metabolic process;GO:0036508//protein alpha-1,2-demannosylation;GO:0048286//lung alveolus development;GO:1904381//Golgi apparatus mannose trimming"	--
ENSG00000198168	3.918	3.255	3.716	3.88	3.567	4.142	364	304	255	267	280	280	SVIP	small VCP interacting protein [Source:HGNC Symbol;Acc:HGNC:25238]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K14014	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030667//secretory granule membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0031225//anchored component of membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0005515//protein binding;GO:0043621//protein self-association;GO:0051117//ATPase binding	"GO:0010508//positive regulation of autophagy;GO:0031333//negative regulation of protein-containing complex assembly;GO:1903061//positive regulation of protein lipidation;GO:1903070//negative regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol;GO:1904240//negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly"	--
ENSG00000198169	4.331	3.573	4.727	3.394	4.135	4.241	257	220	206	154	214	189	ZNF251	zinc finger protein 251 [Source:HGNC Symbol;Acc:HGNC:13045]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0061484//hematopoietic stem cell homeostasis"	zf-C2H2
ENSG00000198171	51.54	63.866	62.36	68.797	63.092	64.051	1388	1721	1233	1370	1424	1252	DDRGK1	DDRGK domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16110]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030335//positive regulation of cell migration;GO:0031647//regulation of protein stability;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051216//cartilage development;GO:0061709//reticulophagy;GO:0070972//protein localization to endoplasmic reticulum;GO:0071569//protein ufmylation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1903895//negative regulation of IRE1-mediated unfolded protein response;GO:1905050//positive regulation of metallopeptidase activity;GO:1905552//positive regulation of protein localization to endoplasmic reticulum;GO:1905636//positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1990592//protein K69-linked ufmylation	--
ENSG00000198173	0	0	0	0	0	0	0	0	0	0	0	0	FAM47C	family with sequence similarity 47 member C [Source:HGNC Symbol;Acc:HGNC:25301]	-	-	-	-	-	-	-	--
ENSG00000198176	19.797	20.051	22.669	20.287	18.231	19.76	995	1026	831	732	752	762	TFDP1	transcription factor Dp-1 [Source:HGNC Symbol;Acc:HGNC:11749]	Cellular Processes;Environmental Information Processing	Cell growth and death;Signal transduction	ko04110//Cell cycle;ko04350//TGF-beta signaling pathway	K04683;K04683	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035189//Rb-E2F complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0008544//epidermis development;GO:0010468//regulation of gene expression;GO:0043276//anoikis;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051726//regulation of cell cycle;GO:0070345//negative regulation of fat cell proliferation;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000278//regulation of DNA biosynthetic process"	E2F
ENSG00000198178	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4C	C-type lectin domain family 4 member C [Source:HGNC Symbol;Acc:HGNC:13258]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0045087//innate immune response;GO:0061760//antifungal innate immune response	--
ENSG00000198182	4.26	3.026	2.596	2.361	4.012	4.401	246	228	158	150	204	175	ZNF607	zinc finger protein 607 [Source:HGNC Symbol;Acc:HGNC:28192]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198183	0	0	0	0	0	0	0	0	0	0	0	0	BPIFA1	BPI fold containing family A member 1 [Source:HGNC Symbol;Acc:HGNC:15749]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008289//lipid binding	GO:0002376//immune system process;GO:0002395//immune response in nasopharyngeal-associated lymphoid tissue;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050828//regulation of liquid surface tension;GO:0050891//multicellular organismal water homeostasis;GO:0051607//defense response to virus;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1900229//negative regulation of single-species biofilm formation in or on host organism;GO:1902305//regulation of sodium ion transmembrane transport	--
ENSG00000198185	3.703	3.056	2.659	2.487	2.448	2.65	229	192	123	117	134	115	ZNF334	zinc finger protein 334 [Source:HGNC Symbol;Acc:HGNC:15806]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198189	14.838	15.444	18.682	21.988	18.381	20.614	544	571	510	602	574	546	HSD17B11	hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid droplet;GO:0005829//cytosol	"GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0006710//androgen catabolic process	--
ENSG00000198198	5.153	5.594	5.93	5.478	6.186	6.367	1377.51	1474.89	1196.7	1072.55	1430.89	1161.45	SZT2	SZT2 subunit of KICSTOR complex [Source:HGNC Symbol;Acc:HGNC:29040]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005777//peroxisome;GO:0016020//membrane;GO:0061700//GATOR2 complex;GO:0140007//KICSTOR complex;GO:1990130//GATOR1 complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007417//central nervous system development;GO:0009791//post-embryonic development;GO:0021540//corpus callosum morphogenesis;GO:0031667//response to nutrient levels;GO:0034198//cellular response to amino acid starvation;GO:0042149//cellular response to glucose starvation;GO:0043473//pigmentation;GO:0061462//protein localization to lysosome;GO:1901668//regulation of superoxide dismutase activity;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000198203	5.245	4.946	4.633	3.984	4.43	4.972	257	234	157	149	178	163	SULT1C2	sulfotransferase family 1C member 2 [Source:HGNC Symbol;Acc:HGNC:11456]	-	-	-	-	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0009308//amine metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000198205	1.689	1.546	1.591	1.325	1.179	1.678	176.17	162.09	122.57	102.4	103.92	127.35	ZXDA	zinc finger X-linked duplicated A [Source:HGNC Symbol;Acc:HGNC:13198]	-	-	-	-	GO:0005634//nucleus	GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070742//C2H2 zinc finger domain binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0045893//positive regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000198208	0.246	0.184	0.326	0.359	0.239	0.191	7	3	4	8	3	3	RPS6KL1	ribosomal protein S6 kinase like 1 [Source:HGNC Symbol;Acc:HGNC:20222]	-	-	-	-	GO:0005840//ribosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000198211	0	0.035	0	0	0	0	0	2.03	0	0	0	0	TUBB3	novel protein (MC1R-TUBB3 readthrough)	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0004930//G protein-coupled receptor activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000198216	0.007	0.044	0	0	0.008	0.02	1	4	0	0	1	3	CACNA1E	calcium voltage-gated channel subunit alpha1 E [Source:HGNC Symbol;Acc:HGNC:1392]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Endocrine and metabolic disease	ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04930//Type II diabetes mellitus	K04852;K04852;K04852	GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0022843//voltage-gated cation channel activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0007268//chemical synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport	--
ENSG00000198218	19.168	25.097	24.428	20.983	21.837	23.893	1288	1569	1215	1039	1238	1168	QRICH1	glutamine rich 1 [Source:HGNC Symbol;Acc:HGNC:24713]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003677//DNA binding;GO:0005515//protein binding	"GO:0006986//response to unfolded protein;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0034976//response to endoplasmic reticulum stress;GO:0036499//PERK-mediated unfolded protein response;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0140467//integrated stress response signaling"	--
ENSG00000198223	0.584	0.501	0.532	0.701	0.327	0.381	22	18	13	14	11	10	CSF2RA	colony stimulating factor 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2435]	Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Cancer: overview;Signaling molecules and interaction;Immune system;Signal transduction	ko05200//Pathways in cancer;ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05066;K05066;K05066;K05066	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030526//granulocyte macrophage colony-stimulating factor receptor complex;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0038023//signaling receptor activity	GO:0006468//protein phosphorylation;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0019221//cytokine-mediated signaling pathway;GO:0038157//granulocyte-macrophage colony-stimulating factor signaling pathway;GO:0070665//positive regulation of leukocyte proliferation	--
ENSG00000198225	0	0	0	0	0	0	0	0	0	0	0	0	FKBP1C	FKBP prolyl isomerase family member 1C [Source:HGNC Symbol;Acc:HGNC:21376]	-	-	-	-	GO:0005737//cytoplasm	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding	--
ENSG00000198231	20.711	20.31	19.401	19.905	18.493	20.677	1625	1645	1167	1026	1237	1113	DDX42	DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12835	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016020//membrane;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0008104//protein localization;GO:0042981//regulation of apoptotic process	--
ENSG00000198242	17.84	18.148	17.766	18.721	15.708	15.575	358	367	264	279	267	228	RPL23A	ribosomal protein L23a [Source:HGNC Symbol;Acc:HGNC:10317]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02893;K02893	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0045296//cadherin binding;GO:1904841//TORC2 complex binding	GO:0000027//ribosomal large subunit assembly;GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000198246	2.574	3.348	2.959	3.362	3.194	2.169	122	159	103	120	128	76	SLC29A3	solute carrier family 29 member 3 [Source:HGNC Symbol;Acc:HGNC:23096]	Human Diseases	Substance dependence	ko05034//Alcoholism	K15014	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005337//nucleoside transmembrane transporter activity;GO:0005515//protein binding	GO:0015858//nucleoside transport;GO:1901642//nucleoside transmembrane transport	--
ENSG00000198252	2.825	2.682	2.201	2.368	2.522	2.03	285	272	164	177	215	149	STYX	serine/threonine/tyrosine interacting protein [Source:HGNC Symbol;Acc:HGNC:11447]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0001691//pseudophosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:1990444//F-box domain binding	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0032091//negative regulation of protein binding;GO:0043086//negative regulation of catalytic activity;GO:0045204//MAPK export from nucleus;GO:0062026//negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process;GO:0070372//regulation of ERK1 and ERK2 cascade	--
ENSG00000198258	37.338	41.053	47.611	50.953	36.792	43.09	321	353	304	323	269	268	UBL5	ubiquitin like 5 [Source:HGNC Symbol;Acc:HGNC:13736]	Organismal Systems	Aging	ko04212//Longevity regulating pathway - worm	K13113	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0031386//protein tag	"GO:0000398//mRNA splicing, via spliceosome;GO:0006464//cellular protein modification process;GO:1903955//positive regulation of protein targeting to mitochondrion"	--
ENSG00000198265	6.567	4.783	5.653	3.433	5.075	5.145	1441	1025	758	592	813	706	HELZ	helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043186//P granule	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0035194//post-transcriptional gene silencing by RNA	--
ENSG00000198270	5.815	6.641	6.286	5.465	5.438	5.733	174	145	130	122	139	122	TMEM116	transmembrane protein 116 [Source:HGNC Symbol;Acc:HGNC:25084]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity	GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008150//biological_process	--
ENSG00000198271	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-5	keratin associated protein 4-5 [Source:HGNC Symbol;Acc:HGNC:18899]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	GO:0007568//aging;GO:0042633//hair cycle	--
ENSG00000198276	7.893	7.436	9.297	7.082	8.06	8.684	294	283	260	198	246	232	UCKL1	uridine-cytidine kinase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:15938]	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00876;K00876;K00876	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004849//uridine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006222//UMP biosynthetic process;GO:0016310//phosphorylation;GO:0043097//pyrimidine nucleoside salvage;GO:0044206//UMP salvage;GO:0044211//CTP salvage	--
ENSG00000198283	0	0	0	0	0	0	0	0	0	0	0	0	OR5B21	olfactory receptor family 5 subfamily B member 21 [Source:HGNC Symbol;Acc:HGNC:19616]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198286	0.457	0.347	0.183	0.38	0.359	0.34	21	31	12	25	27	22	CARD11	caspase recruitment domain family member 11 [Source:HGNC Symbol;Acc:HGNC:16393]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Immune system;Immune system	ko04064//NF-kappa B signaling pathway;ko04662//B cell receptor signaling pathway;ko04660//T cell receptor signaling pathway	K07367;K07367;K07367	GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0032449//CBM complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0004385//guanylate kinase activity;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0050700//CARD domain binding	GO:0002376//immune system process;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030183//B cell differentiation;GO:0030890//positive regulation of B cell proliferation;GO:0031295//T cell costimulation;GO:0032743//positive regulation of interleukin-2 production;GO:0038202//TORC1 signaling;GO:0042100//B cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045061//thymic T cell selection;GO:0045577//regulation of B cell differentiation;GO:0045580//regulation of T cell differentiation;GO:0046037//GMP metabolic process;GO:0046649//lymphocyte activation;GO:0046710//GDP metabolic process;GO:0048872//homeostasis of number of cells;GO:0050776//regulation of immune response;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization	--
ENSG00000198298	0.667	0.664	0.806	0.45	0.282	0.393	28	28	25	14	10	12	ZNF485	zinc finger protein 485 [Source:HGNC Symbol;Acc:HGNC:23440]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198300	0	0	0.012	0	0.021	0.043	0	0	1	0	3	1	PEG3	paternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:8826]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005776//autophagosome	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000198301	10.224	9.575	7.413	6.683	6.931	7.706	594	542	333	262	364	297	SDAD1	SDA1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25537]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003674//molecular_function	GO:0000055//ribosomal large subunit export from nucleus;GO:0015031//protein transport;GO:0030036//actin cytoskeleton organization;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis	--
ENSG00000198315	13.347	12.152	12.248	9.694	11.722	13.954	1994	1835	1392	1105	1488	1453	ZKSCAN8	zinc finger with KRAB and SCAN domains 8 [Source:HGNC Symbol;Acc:HGNC:12983]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198324	4.981	4.673	4.267	6.59	6.331	5.72	276	293	205	263	260	236	PHETA1	PH domain containing endocytic trafficking adaptor 1 [Source:HGNC Symbol;Acc:HGNC:26509]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	"GO:0001881//receptor recycling;GO:0007032//endosome organization;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000198326	0	0	0	0	0	0	0	0	0	0	0	0	TMEM239	transmembrane protein 239 [Source:HGNC Symbol;Acc:HGNC:40044]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000198331	3.522	3.835	3.779	3.339	2.556	3.261	106	116	84	75	65	73	HYLS1	HYLS1 centriolar and ciliogenesis associated [Source:HGNC Symbol;Acc:HGNC:26558]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0042995//cell projection;GO:0097730//non-motile cilium	GO:0005515//protein binding	GO:0030030//cell projection organization;GO:0060271//cilium assembly	--
ENSG00000198336	0.057	0.899	0	0.153	0.533	0.103	1	15	0	2	6	1	MYL4	myosin light chain 4 [Source:HGNC Symbol;Acc:HGNC:7585]	Organismal Systems;Environmental Information Processing;Organismal Systems	Circulatory system;Signal transduction;Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04260//Cardiac muscle contraction	K12750;K12750;K12750	GO:0005829//cytosol;GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0031672//A band	GO:0003785//actin monomer binding;GO:0005509//calcium ion binding;GO:0032038//myosin II heavy chain binding;GO:0051015//actin filament binding	GO:0002026//regulation of the force of heart contraction;GO:0032781//positive regulation of ATPase activity;GO:0060048//cardiac muscle contraction	--
ENSG00000198342	0.264	0.161	0.252	0.173	0.179	0.011	12	9	9	5	7	1	ZNF442	zinc finger protein 442 [Source:HGNC Symbol;Acc:HGNC:20877]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198346	1.026	0.838	0.726	0.624	0.556	0.635	131	107.45	68.43	59	60	59	ZNF813	zinc finger protein 813 [Source:HGNC Symbol;Acc:HGNC:33257]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198353	0	0	0.076	0	0	0	0	0	2	0	0	0	HOXC4	homeobox C4 [Source:HGNC Symbol;Acc:HGNC:5126]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048562//embryonic organ morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0051216//cartilage development"	Homeobox
ENSG00000198354	1.537	1.65	1.146	2.682	2.678	2.137	89	96	49	115	131	90	DCAF12L2	DDB1 and CUL4 associated factor 12 like 2 [Source:HGNC Symbol;Acc:HGNC:32950]	-	-	-	-	GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	-	--
ENSG00000198355	10.275	10.017	11.18	13.376	14.144	19.071	448	439	360	432	521	605	PIM3	"Pim-3 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:19310]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus	--
ENSG00000198356	63.925	67.992	63.653	75.374	65.451	69.327	1695	1811	1244	1481	1466	1334	GET3	"guided entry of tail-anchored proteins factor 3, ATPase [Source:HGNC Symbol;Acc:HGNC:752]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0043529//GET complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015105//arsenite transmembrane transporter activity;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0015700//arsenite transport;GO:0045048//protein insertion into ER membrane;GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000198363	57.704	50.251	49.117	40.939	52.524	56.222	3968.89	3400.7	2476	2123.33	2782.76	2699.46	ASPH	aspartate beta-hydroxylase [Source:HGNC Symbol;Acc:HGNC:757]	Environmental Information Processing;Organismal Systems	Signal transduction;Circulatory system	ko04020//Calcium signaling pathway;ko04260//Cardiac muscle contraction	K00476;K00476	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032541//cortical endoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0034704//calcium channel complex	GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0062101//peptidyl-aspartic acid 3-dioxygenase activity	"GO:0005513//detection of calcium ion;GO:0006936//muscle contraction;GO:0007389//pattern specification process;GO:0008285//negative regulation of cell population proliferation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0010649//regulation of cell communication by electrical coupling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0018193//peptidyl-amino acid modification;GO:0022900//electron transport chain;GO:0031585//regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0031647//regulation of protein stability;GO:0032237//activation of store-operated calcium channel activity;GO:0033198//response to ATP;GO:0035108//limb morphogenesis;GO:0042264//peptidyl-aspartic acid hydroxylation;GO:0045862//positive regulation of proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0055074//calcium ion homeostasis;GO:0060021//roof of mouth development;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0060325//face morphogenesis;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0090316//positive regulation of intracellular protein transport;GO:0097202//activation of cysteine-type endopeptidase activity;GO:1901879//regulation of protein depolymerization"	--
ENSG00000198369	5.494	6.156	6.942	7.044	7.028	7.576	515	543	440	464	485	491	SPRED2	sprouty related EVH1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17722]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0005173//stem cell factor receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity	"GO:0001933//negative regulation of protein phosphorylation;GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0043409//negative regulation of MAPK cascade;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0090311//regulation of protein deacetylation;GO:1902747//negative regulation of lens fiber cell differentiation"	--
ENSG00000198373	20.064	20.295	21.883	21.765	22.513	20.827	1654	1651	1263	1303	1479	1209	WWP2	WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16804]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K05630	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0016740//transferase activity;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006858//extracellular transport;GO:0010629//negative regulation of gene expression;GO:0016567//protein ubiquitination;GO:0032410//negative regulation of transporter activity;GO:0034765//regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045732//positive regulation of protein catabolic process;GO:0045746//negative regulation of Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046718//viral entry into host cell;GO:0051224//negative regulation of protein transport;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:1901016//regulation of potassium ion transmembrane transporter activity"	--
ENSG00000198380	28.352	24.309	24.561	19.664	21.143	23.697	3018	2536	1919	1500	1793	1751	GFPT1	glutamine--fructose-6-phosphate transaminase 1 [Source:HGNC Symbol;Acc:HGNC:4241]	Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko05415//Diabetic cardiomyopathy;ko04931//Insulin resistance;ko00520//Amino sugar and nucleotide sugar metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K00820;K00820;K00820;K00820;K00820	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity;GO:0008483//transaminase activity;GO:0016740//transferase activity;GO:0097367//carbohydrate derivative binding	GO:0006002//fructose 6-phosphate metabolic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006541//glutamine metabolic process;GO:0032922//circadian regulation of gene expression;GO:0048511//rhythmic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901137//carbohydrate derivative biosynthetic process	--
ENSG00000198382	13.269	10.731	12.825	16.509	12.039	15.017	857	840	694	699	738	758	UVRAG	UV radiation resistance associated [Source:HGNC Symbol;Acc:HGNC:12640]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21249	"GO:0000323//lytic vacuole;GO:0000421//autophagosome membrane;GO:0000775//chromosome, centromeric region;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0030496//midbody;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0035032//phosphatidylinositol 3-kinase complex, class III;GO:0045335//phagocytic vesicle;GO:0070418//DNA-dependent protein kinase complex"	GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding	"GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006914//autophagy;GO:0006974//cellular response to DNA damage stimulus;GO:0007051//spindle organization;GO:0007059//chromosome segregation;GO:0007098//centrosome cycle;GO:0010506//regulation of autophagy;GO:0032465//regulation of cytokinesis;GO:0032801//receptor catabolic process;GO:0035493//SNARE complex assembly;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0046718//viral entry into host cell;GO:0051684//maintenance of Golgi location;GO:0071900//regulation of protein serine/threonine kinase activity;GO:0071985//multivesicular body sorting pathway;GO:0097352//autophagosome maturation;GO:0097680//double-strand break repair via classical nonhomologous end joining;GO:1901098//positive regulation of autophagosome maturation"	--
ENSG00000198390	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP13-1	keratin associated protein 13-1 [Source:HGNC Symbol;Acc:HGNC:18924]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000198393	0.689	0.655	1.792	0.319	0.87	0.393	138	121	69	55	72	60	ZNF26	zinc finger protein 26 [Source:HGNC Symbol;Acc:HGNC:13053]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198398	0	0	0	0	0	0	0	0	0	0	0	0	TMEM207	transmembrane protein 207 [Source:HGNC Symbol;Acc:HGNC:33705]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000198399	5.195	3.475	3.547	1.909	2.704	3.354	454	343	239	144	240	228	ITSN2	intersectin 2 [Source:HGNC Symbol;Acc:HGNC:6184]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0070062//extracellular exosome;GO:0098793//presynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0060090//molecular adaptor activity	GO:0006897//endocytosis;GO:0016197//endosomal transport;GO:0030154//cell differentiation;GO:0050790//regulation of catalytic activity;GO:0150007//clathrin-dependent synaptic vesicle endocytosis;GO:1903861//positive regulation of dendrite extension	--
ENSG00000198400	0	0.019	0	0	0.023	0	0	1	0	0	1	0	NTRK1	neurotrophic receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:8031]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Signal transduction;Cell growth and death;Nervous system;Sensory system;Cancer: overview;Cancer: specific types	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko04210//Apoptosis;ko04722//Neurotrophin signaling pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05230//Central carbon metabolism in cancer;ko05216//Thyroid cancer	K03176;K03176;K03176;K03176;K03176;K03176;K03176;K03176;K03176;K03176;K03176	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032991//protein-containing complex;GO:0043025//neuronal cell body;GO:0043235//receptor complex;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005030//neurotrophin receptor activity;GO:0005166//neurotrophin p75 receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0010465//nerve growth factor receptor activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043121//neurotrophin binding;GO:0048406//nerve growth factor binding	"GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007568//aging;GO:0007611//learning or memory;GO:0007623//circadian rhythm;GO:0008285//negative regulation of cell population proliferation;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0010623//programmed cell death involved in cell development;GO:0010976//positive regulation of neuron projection development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019233//sensory perception of pain;GO:0021553//olfactory nerve development;GO:0030154//cell differentiation;GO:0030183//B cell differentiation;GO:0031175//neuron projection development;GO:0031667//response to nutrient levels;GO:0033674//positive regulation of kinase activity;GO:0035094//response to nicotine;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0038179//neurotrophin signaling pathway;GO:0038180//nerve growth factor signaling pathway;GO:0042490//mechanoreceptor differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0046777//protein autophosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0048485//sympathetic nervous system development;GO:0048666//neuron development;GO:0048678//response to axon injury;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051599//response to hydrostatic pressure;GO:0051602//response to electrical stimulus;GO:0051896//regulation of protein kinase B signaling;GO:0051965//positive regulation of synapse assembly;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060009//Sertoli cell development;GO:0060384//innervation;GO:0060385//axonogenesis involved in innervation;GO:0061368//behavioral response to formalin induced pain;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071316//cellular response to nicotine;GO:0071363//cellular response to growth factor stimulus;GO:1901215//negative regulation of neuron death;GO:1990090//cellular response to nerve growth factor stimulus"	--
ENSG00000198408	16.167	15.86	14.02	14.541	14.097	11.669	1681	1635	1024	1003	1215	838	OGA	O-GlcNAcase [Source:HGNC Symbol;Acc:HGNC:7056]	Human Diseases	Endocrine and metabolic disease	ko04931//Insulin resistance	K15719	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	"GO:0004415//hyalurononglucosaminidase activity;GO:0016231//beta-N-acetylglucosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0102166//[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity;GO:0102167//[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity;GO:0102571//[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity"	GO:0006044//N-acetylglucosamine metabolic process;GO:0006464//cellular protein modification process;GO:0006493//protein O-linked glycosylation;GO:0006516//glycoprotein catabolic process;GO:0006517//protein deglycosylation;GO:0008152//metabolic process;GO:0009100//glycoprotein metabolic process	--
ENSG00000198417	11.233	8.239	8.755	7.657	4.431	9.978	99	73	57	50	33	64	MT1F	metallothionein 1F [Source:HGNC Symbol;Acc:HGNC:7398]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000198420	18.224	14.579	12.324	8.183	10.685	11.381	1714	1364	892	580	832	713	TCAF1	TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0044325//transmembrane transporter binding	GO:0010359//regulation of anion channel activity;GO:0030336//negative regulation of cell migration;GO:0090314//positive regulation of protein targeting to membrane;GO:1901529//positive regulation of anion channel activity	--
ENSG00000198429	0.947	1.371	1.213	1.131	1.486	2.028	29	36	21	29	28	33	ZNF69	zinc finger protein 69 [Source:HGNC Symbol;Acc:HGNC:13138]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198431	39.633	41.058	44.839	41.256	49.948	57.961	2522	2469	2057	2085	2287	2554	TXNRD1	thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437]	Human Diseases;Human Diseases;Metabolism	Cancer: overview;Cancer: specific types;Metabolism of other amino acids	ko05200//Pathways in cancer;ko05225//Hepatocellular carcinoma;ko00450//Selenocompound metabolism	K22182;K22182;K22182	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004791//thioredoxin-disulfide reductase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor;GO:0042802//identical protein binding;GO:0050137//NADPH peroxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0071949//FAD binding;GO:0097573//glutathione oxidoreductase activity"	GO:0001707//mesoderm formation;GO:0007165//signal transduction;GO:0007369//gastrulation;GO:0008283//cell population proliferation;GO:0045454//cell redox homeostasis;GO:0098869//cellular oxidant detoxification	--
ENSG00000198435	0.584	0.872	0.766	0.739	1.059	0.928	32	48	31	30	49	37	NRARP	NOTCH regulated ankyrin repeat protein [Source:HGNC Symbol;Acc:HGNC:33843]	-	-	-	-	-	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007219//Notch signaling pathway;GO:0022407//regulation of cell-cell adhesion;GO:0032525//somite rostral/caudal axis specification;GO:0045581//negative regulation of T cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902367//negative regulation of Notch signaling pathway involved in somitogenesis	--
ENSG00000198440	1.577	1.777	1.223	2.02	2.594	1.459	101	91	52	66	87	43	ZNF583	zinc finger protein 583 [Source:HGNC Symbol;Acc:HGNC:26427]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198443	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-1	keratin associated protein 4-1 [Source:HGNC Symbol;Acc:HGNC:18907]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000198445	0	0	0	0	0	0	0	0	0	0	0	0	CCT8L2	chaperonin containing TCP1 subunit 8 like 2 [Source:HGNC Symbol;Acc:HGNC:15553]	-	-	-	-	GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex	GO:0000166//nucleotide binding;GO:0005253//anion channel activity;GO:0005524//ATP binding;GO:0015269//calcium-activated potassium channel activity;GO:0016887//ATP hydrolysis activity;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0015698//inorganic anion transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000198452	0	0	0	0	0	0	0	0	0	0	0	0	OR14L1P	olfactory receptor family 14 subfamily L member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:15023]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198453	2.509	2.111	2.077	1.263	1.305	1.908	155	117	85	65	72	72	ZNF568	zinc finger protein 568 [Source:HGNC Symbol;Acc:HGNC:25392]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060669//embryonic placenta morphogenesis"	zf-C2H2
ENSG00000198455	3.508	3.491	3.48	3.21	3.351	3.886	397.83	397.91	291.43	269.6	321.08	320.65	ZXDB	zinc finger X-linked duplicated B [Source:HGNC Symbol;Acc:HGNC:13199]	-	-	-	-	GO:0005634//nucleus	GO:0003674//molecular_function;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process	zf-C2H2
ENSG00000198464	1.964	2.094	1.544	1.756	1.238	1.313	183	138	67	56	103	85	ZNF480	zinc finger protein 480 [Source:HGNC Symbol;Acc:HGNC:23305]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198466	4.186	4.17	3.338	2.269	3.17	2.922	413.06	351.55	235.33	202.96	260.56	224.28	ZNF587	zinc finger protein 587 [Source:HGNC Symbol;Acc:HGNC:30955]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198467	214.652	221.252	206.316	221.822	214.964	208.531	5080	5261	3589	3872	4262	3585	TPM2	tropomyosin 2 [Source:HGNC Symbol;Acc:HGNC:12011]	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Cardiovascular disease;Circulatory system;Cardiovascular disease;Circulatory system	ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction	K10374;K10374;K10374;K10374	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005862//muscle thin filament tropomyosin;GO:0005884//actin filament;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0043462//regulation of ATPase activity	--
ENSG00000198471	0	0	0	0	0	0	0	0	0	0	0	0	RTP2	receptor transporter protein 2 [Source:HGNC Symbol;Acc:HGNC:32486]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0031849//olfactory receptor binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006612//protein targeting to membrane;GO:0051205//protein insertion into membrane	--
ENSG00000198478	6.515	6.492	6.722	5.062	5.232	5.398	622	623	474	358	422	375	SH3BGRL2	SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane	GO:0017124//SH3 domain binding	-	--
ENSG00000198482	1.875	0.871	1.779	0.576	0.837	1.151	84	58	52	35	55	41	ZNF808	zinc finger protein 808 [Source:HGNC Symbol;Acc:HGNC:33230]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198483	0.125	0.233	0	0.063	0.203	0.086	8	15	0	3	11	4	ANKRD35	ankyrin repeat domain 35 [Source:HGNC Symbol;Acc:HGNC:26323]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000198488	0	0	0	0	0	0	0	0	0	0	0	0	B3GNT6	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:24141]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00512//Mucin type O-glycan biosynthesis	K00739;K00739	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031984//organelle subcompartment	"GO:0008194//UDP-glycosyltransferase activity;GO:0008378//galactosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0047224//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0106327//acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0106328//acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"	"GO:0006486//protein glycosylation;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing;GO:0016269//O-glycan processing, core 3;GO:0030311//poly-N-acetyllactosamine biosynthetic process"	--
ENSG00000198492	26.053	25.315	24.593	22.486	22.398	28.071	1478	1448	1028	948	1077	1150	YTHDF2	YTH N6-methyladenosine RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:31675]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0034451//centriolar satellite;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0062153//C5-methylcytidine-containing RNA binding;GO:1990247//N6-methyladenosine-containing RNA binding	GO:0001556//oocyte maturation;GO:0002376//immune system process;GO:0006402//mRNA catabolic process;GO:0006959//humoral immune response;GO:0007049//cell cycle;GO:0007276//gamete generation;GO:0007283//spermatogenesis;GO:0007284//spermatogonial cell division;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0034063//stress granule assembly;GO:0043488//regulation of mRNA stability;GO:0045087//innate immune response;GO:0045746//negative regulation of Notch signaling pathway;GO:0048477//oogenesis;GO:0048598//embryonic morphogenesis;GO:0050767//regulation of neurogenesis;GO:0051301//cell division;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061157//mRNA destabilization;GO:0070925//organelle assembly;GO:0071425//hematopoietic stem cell proliferation;GO:0098508//endothelial to hematopoietic transition;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1903538//regulation of meiotic cell cycle process involved in oocyte maturation;GO:1903679//positive regulation of cap-independent translational initiation;GO:2000232//regulation of rRNA processing;GO:2000737//negative regulation of stem cell differentiation	--
ENSG00000198498	3.798	3.184	3.718	3.238	4.373	3.557	119	107	80	78	108	80	TMA16	translation machinery associated 16 homolog [Source:HGNC Symbol;Acc:HGNC:25638]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	-	--
ENSG00000198502	0.386	0.614	0.783	0.312	0.046	0.212	10	16	15	6	1	4	HLA-DRB5	"major histocompatibility complex, class II, DR beta 5 [Source:HGNC Symbol;Acc:HGNC:4953]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0023026//MHC class II protein complex binding;GO:0042605//peptide antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000198513	0.964	0.97	0.665	0.49	1.01	0.357	76.49	77.72	25.51	29.27	54.46	13.49	ATL1	atlastin GTPase 1 [Source:HGNC Symbol;Acc:HGNC:11231]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0071782//endoplasmic reticulum tubular network;GO:0098826//endoplasmic reticulum tubular network membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0007029//endoplasmic reticulum organization;GO:0007409//axonogenesis;GO:0051260//protein homooligomerization;GO:1990809//endoplasmic reticulum tubular network membrane organization	--
ENSG00000198515	0.018	0.033	0.024	0.024	0	0.024	1	2	1	1	0	1	CNGA1	cyclic nucleotide gated channel subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:2148]	Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Sensory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04744//Phototransduction	K04948;K04948;K04948	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042622//photoreceptor outer segment membrane	GO:0000166//nucleotide binding;GO:0005216//ion channel activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005222//intracellular cAMP-activated cation channel activity;GO:0005223//intracellular cGMP-activated cation channel activity;GO:0005515//protein binding;GO:0030553//cGMP binding	GO:0006811//ion transport;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0098655//cation transmembrane transport	--
ENSG00000198517	3.974	5.335	5.542	3.937	4.447	4.71	265.79	354.17	277.79	199	249.44	229.43	MAFK	MAF bZIP transcription factor K [Source:HGNC Symbol;Acc:HGNC:6782]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	TF_bZIP
ENSG00000198520	0.274	0.554	0.774	1.112	0.746	0.374	7	19	9	13	13	6	ARMH1	armadillo like helical domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34345]	-	-	-	-	-	-	-	--
ENSG00000198521	5.746	4.373	4.518	3.506	3.854	3.346	478	335	263	171	247.02	204	ZNF43	zinc finger protein 43 [Source:HGNC Symbol;Acc:HGNC:13109]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198522	14.582	13.384	13.673	11.63	11.874	11.354	556.75	526.96	374.88	336.77	390.15	329.22	GPN1	GPN-loop GTPase 1 [Source:HGNC Symbol;Acc:HGNC:17030]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	-	--
ENSG00000198523	0	0.016	0	0	0	0	0	1	0	0	0	0	PLN	phospholamban [Source:HGNC Symbol;Acc:HGNC:9080]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Cardiovascular disease;Circulatory system;Endocrine system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko05414//Dilated cardiomyopathy;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway	K05852;K05852;K05852;K05852;K05852;K05852;K05852	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0031966//mitochondrial membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0090534//calcium ion-transporting ATPase complex	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0042030//ATPase inhibitor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051117//ATPase binding	GO:0002026//regulation of the force of heart contraction;GO:0006874//cellular calcium ion homeostasis;GO:0007219//Notch signaling pathway;GO:0008015//blood circulation;GO:0008016//regulation of heart contraction;GO:0010459//negative regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0032780//negative regulation of ATPase activity;GO:0043086//negative regulation of catalytic activity;GO:0044092//negative regulation of molecular function;GO:0045822//negative regulation of heart contraction;GO:0048738//cardiac muscle tissue development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051924//regulation of calcium ion transport;GO:0051926//negative regulation of calcium ion transport;GO:0055119//relaxation of cardiac muscle;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0086004//regulation of cardiac muscle cell contraction;GO:0086023//adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0086092//regulation of the force of heart contraction by cardiac conduction;GO:0090279//regulation of calcium ion import;GO:0090281//negative regulation of calcium ion import;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1901077//regulation of relaxation of muscle;GO:1901877//negative regulation of calcium ion binding;GO:1901894//regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1901897//regulation of relaxation of cardiac muscle;GO:1902081//negative regulation of calcium ion import into sarcoplasmic reticulum	--
ENSG00000198535	0.07	0	0	0	0.017	0	5	0	0	0	1	0	C2CD4A	C2 calcium dependent domain containing 4A [Source:HGNC Symbol;Acc:HGNC:33627]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	-	GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0002675//positive regulation of acute inflammatory response;GO:0030155//regulation of cell adhesion	--
ENSG00000198538	6.661	4.476	4.684	3.48	3.5	5.688	422.4	299.9	196	147	230	223	ZNF28	zinc finger protein 28 [Source:HGNC Symbol;Acc:HGNC:13073]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198542	0.024	0.048	0.027	0	0.065	0.033	1	2	1	0	2.15	1	ITGBL1	integrin subunit beta like 1 [Source:HGNC Symbol;Acc:HGNC:6164]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005925//focal adhesion	GO:0005178//integrin binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0033627//cell adhesion mediated by integrin	--
ENSG00000198546	10.8	11.236	11.416	14.328	13.465	13.888	250	262.76	195	249	264.9	235.87	ZNF511	zinc finger protein 511 [Source:HGNC Symbol;Acc:HGNC:28445]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	Others
ENSG00000198547	0	0	0	0	0	0	0	0	0	0	0	0	C20orf203	chromosome 20 open reading frame 203 [Source:HGNC Symbol;Acc:HGNC:26592]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000198551	7.723	7.325	7.732	4.876	5.76	6.453	449	413	332	210	260	273	ZNF627	zinc finger protein 627 [Source:HGNC Symbol;Acc:HGNC:30570]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198553	0.089	0.313	0.138	0	0	0.078	2.48	10.59	3.43	0	0	1.91	KCNRG	potassium channel regulator [Source:HGNC Symbol;Acc:HGNC:18893]	-	-	-	-	GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0051260//protein homooligomerization;GO:1902260//negative regulation of delayed rectifier potassium channel activity	--
ENSG00000198554	1.773	1.357	1.174	0.648	1.063	0.686	154	127	79	55	71	42	WDHD1	WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043596//nuclear replication fork	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0000278//mitotic cell cycle;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair	HMG
ENSG00000198556	3.373	4.658	3.057	3.821	3.879	2.541	151	177	117	126	156	82	ZNF789	zinc finger protein 789 [Source:HGNC Symbol;Acc:HGNC:27801]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198561	50.098	47.954	44.724	39.485	48.39	38.848	5500.33	5542.87	3854.35	3393.14	4743.34	3236.46	CTNND1	catenin delta 1 [Source:HGNC Symbol;Acc:HGNC:2515]	Environmental Information Processing;Organismal Systems;Cellular Processes	Signal transduction;Immune system;Cellular community - eukaryotes	ko04015//Rap1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04520//Adherens junction	K05690;K05690;K05690	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005912//adherens junction;GO:0005915//zonula adherens;GO:0016020//membrane;GO:0016342//catenin complex;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030426//growth cone;GO:0030496//midbody;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098686//hippocampal mossy fiber to CA3 synapse;GO:0098831//presynaptic active zone cytoplasmic component;GO:0098978//glutamatergic synapse;GO:0099092//postsynaptic density, intracellular component"	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding;GO:0050839//cell adhesion molecule binding	GO:0007043//cell-cell junction assembly;GO:0007155//cell adhesion;GO:0007420//brain development;GO:0016055//Wnt signaling pathway;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0050821//protein stabilization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0098609//cell-cell adhesion;GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels	--
ENSG00000198563	50.166	51.264	52.48	57.687	59.3	49.366	1646.92	1743.06	1280.93	1373.04	1645.86	1219.08	DDX39B	DExD-box helicase 39B [Source:HGNC Symbol;Acc:HGNC:13917]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12812;K12812;K12812	GO:0000346//transcription export complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005687//U4 snRNP;GO:0005688//U6 snRNP;GO:0005737//cytoplasm;GO:0016607//nuclear speck	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008186//ATP-dependent activity, acting on RNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017070//U6 snRNA binding;GO:0030621//U4 snRNA binding;GO:0042802//identical protein binding;GO:0043008//ATP-dependent protein binding"	"GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006405//RNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0010501//RNA secondary structure unwinding;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0046784//viral mRNA export from host cell nucleus;GO:0051028//mRNA transport;GO:2000002//negative regulation of DNA damage checkpoint"	--
ENSG00000198569	0	0.071	0.097	0.065	0.17	0.066	0	3	3	2	6	2	SLC34A3	solute carrier family 34 member 3 [Source:HGNC Symbol;Acc:HGNC:20305]	Organismal Systems;Organismal Systems	Endocrine system;Digestive system	"ko04928//Parathyroid hormone synthesis, secretion and action;ko04978//Mineral absorption"	K14683;K14683	GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031982//vesicle	GO:0005436//sodium:phosphate symporter activity;GO:0005515//protein binding;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006817//phosphate ion transport;GO:0030643//cellular phosphate ion homeostasis;GO:0035725//sodium ion transmembrane transport;GO:0044341//sodium-dependent phosphate transport;GO:0055085//transmembrane transport	--
ENSG00000198570	0.069	0.068	0.093	0	0.081	0.019	5	5	5	0	5	1	RD3	RD3 regulator of GUCY2D [Source:HGNC Symbol;Acc:HGNC:19689]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0007601//visual perception;GO:0015031//protein transport;GO:0031283//negative regulation of guanylate cyclase activity;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye	--
ENSG00000198573	0	0	0	0	0	0	0	0	0	0	0	0	SPANXC	SPANX family member C [Source:HGNC Symbol;Acc:HGNC:14331]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000198574	0	0	0	0	0	0	0	0	0	0	0	0	SH2D1B	SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07989	GO:0005829//cytosol	GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity	GO:0002250//adaptive immune response;GO:0002366//leukocyte activation involved in immune response;GO:0002376//immune system process;GO:0002717//positive regulation of natural killer cell mediated immunity;GO:0045087//innate immune response;GO:0045089//positive regulation of innate immune response	--
ENSG00000198576	0.49	0.797	0.376	0.265	0.387	0.135	30	49	17	12	20	6	ARC	activity regulated cytoskeleton associated protein [Source:HGNC Symbol;Acc:HGNC:648]	Human Diseases	Substance dependence	ko05031//Amphetamine addiction	K15867	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0071598//neuronal ribonucleoprotein granule;GO:0098839//postsynaptic density membrane;GO:0098845//postsynaptic endosome;GO:0098978//glutamatergic synapse;GO:1903561//extracellular vesicle	GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0007492//endoderm development;GO:0007612//learning;GO:0007616//long-term memory;GO:0009952//anterior/posterior pattern specification;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0050804//modulation of chemical synaptic transmission;GO:0051028//mRNA transport;GO:0051260//protein homooligomerization;GO:0060291//long-term synaptic potentiation;GO:0060997//dendritic spine morphogenesis;GO:0061001//regulation of dendritic spine morphogenesis;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:0110077//vesicle-mediated intercellular transport;GO:1900271//regulation of long-term synaptic potentiation;GO:1900452//regulation of long-term synaptic depression;GO:2000969//positive regulation of AMPA receptor activity	--
ENSG00000198585	10.044	10.215	9.887	8.784	9.038	9.21	1165	1097	855	756	883	770	NUDT16	nudix hydrolase 16 [Source:HGNC Symbol;Acc:HGNC:26442]	Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Nucleotide metabolism;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko03018//RNA degradation	K16855;K16855;K16855	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005525//GTP binding;GO:0008235//metalloexopeptidase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0030515//snoRNA binding;GO:0031404//chloride ion binding;GO:0035870//dITP diphosphatase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0050897//cobalt ion binding;GO:0097383//dIDP diphosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:0110153//RNA NAD-cap (NMN-forming) hydrolase activity;GO:1901640//XTP binding;GO:1901641//ITP binding;GO:1990003//inosine-diphosphatase activity;GO:1990174//phosphodiesterase decapping endonuclease activity"	"GO:0006382//adenosine to inosine editing;GO:0006402//mRNA catabolic process;GO:0006508//proteolysis;GO:0009117//nucleotide metabolic process;GO:0016077//sno(s)RNA catabolic process;GO:0016311//dephosphorylation;GO:0035863//dITP catabolic process;GO:0046709//IDP catabolic process;GO:0090068//positive regulation of cell cycle process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0110155//NAD-cap decapping;GO:2000233//negative regulation of rRNA processing"	--
ENSG00000198586	11.166	8.053	7.527	6.422	8.132	8.908	846	646	454	354	500	494	TLK1	tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0001672//regulation of chromatin assembly or disassembly;GO:0006325//chromatin organization;GO:0006468//protein phosphorylation;GO:0006886//intracellular protein transport;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction	--
ENSG00000198589	36.952	33.362	35.661	28.808	31.463	31.624	4286	3744	2789	2254	2906	2602	LRBA	LPS responsive beige-like anchor protein [Source:HGNC Symbol;Acc:HGNC:1742]	-	-	-	-	GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043226//organelle	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0000423//mitophagy;GO:0008104//protein localization;GO:0034497//protein localization to phagophore assembly site	--
ENSG00000198597	8.26	9.661	9.179	9.462	10.361	11.052	714	741	586	600	729	677	ZNF536	zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0048387//negative regulation of retinoic acid receptor signaling pathway"	zf-C2H2
ENSG00000198598	1.1	1.267	0.498	0.27	0.355	0.496	55	52	17	10	15	14	MMP17	matrix metallopeptidase 17 [Source:HGNC Symbol;Acc:HGNC:7163]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K07997	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane	GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0001822//kidney development;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0042756//drinking behavior;GO:0050790//regulation of catalytic activity	--
ENSG00000198601	0	0	0	0	0	0	0	0	0	0	0	0	OR2M2	olfactory receptor family 2 subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:8268]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198604	0.945	0.875	0.698	1.088	0.58	0.839	115	107	63	56	59	54	BAZ1A	bromodomain adjacent to zinc finger domain 1A [Source:HGNC Symbol;Acc:HGNC:960]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005721//pericentric heterochromatin;GO:0008623//CHRAC;GO:0016590//ACF complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006261//DNA-dependent DNA replication;GO:0006275//regulation of DNA replication;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016584//nucleosome positioning;GO:0042766//nucleosome mobilization;GO:0045740//positive regulation of DNA replication	--
ENSG00000198610	0	0	0	0	0	0	0	0	0	0	0	0	AKR1C4	aldo-keto reductase family 1 member C4 [Source:HGNC Symbol;Acc:HGNC:387]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00140//Steroid hormone biosynthesis;ko00120//Primary bile acid biosynthesis	K00037;K00037;K00037;K00037	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	"GO:0001758//retinal dehydrogenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0009055//electron transfer activity;GO:0015125//bile acid transmembrane transporter activity;GO:0016229//steroid dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0032052//bile acid binding;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047023//androsterone dehydrogenase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047044//androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047743//chlordecone reductase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0015721//bile acid and bile salt transport;GO:0022900//electron transport chain;GO:0042448//progesterone metabolic process;GO:0044597//daunorubicin metabolic process;GO:0044598//doxorubicin metabolic process;GO:0071395//cellular response to jasmonic acid stimulus	--
ENSG00000198612	42.155	45.592	42.058	42.57	34.047	40.63	1317	1429	1004	987	921	952	COPS8	COP9 signalosome subunit 8 [Source:HGNC Symbol;Acc:HGNC:24335]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0000338//protein deneddylation;GO:0006468//protein phosphorylation;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0008285//negative regulation of cell population proliferation;GO:0010387//COP9 signalosome assembly;GO:0045116//protein neddylation;GO:2000434//regulation of protein neddylation	--
ENSG00000198624	7.364	10.081	7.123	7.279	7.154	8.486	519	558	352	380	426	373	CCDC69	coiled-coil domain containing 69 [Source:HGNC Symbol;Acc:HGNC:24487]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody;GO:0051233//spindle midzone	GO:0008017//microtubule binding	GO:0051255//spindle midzone assembly	--
ENSG00000198625	1.351	0.965	1.066	1.524	1.132	2.311	212	186	164	156	199	222	MDM4	MDM4 regulator of p53 [Source:HGNC Symbol;Acc:HGNC:6974]	Human Diseases;Cellular Processes	Cancer: overview;Cell growth and death	ko05206//MicroRNAs in cancer;ko04115//p53 signaling pathway	K10127;K10127	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex	GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003170//heart valve development;GO:0003181//atrioventricular valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008285//negative regulation of cell population proliferation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0051726//regulation of cell cycle;GO:0065003//protein-containing complex assembly;GO:0071456//cellular response to hypoxia"	--
ENSG00000198626	1.315	0.803	0.853	0.559	0.46	0.32	290	240	160	93	118	80	RYR2	ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Signal transduction;Cardiovascular disease;Cardiovascular disease;Endocrine system;Circulatory system;Signal transduction;Digestive system;Environmental adaptation;Cardiovascular disease;Circulatory system;Endocrine system;Cardiovascular disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05415//Diabetic cardiomyopathy;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04972//Pancreatic secretion;ko04713//Circadian entrainment;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962;K04962	GO:0005790//smooth endoplasmic reticulum;GO:0005886//plasma membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030659//cytoplasmic vesicle membrane;GO:0032991//protein-containing complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex;GO:0042383//sarcolemma	GO:0005216//ion channel activity;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015278//calcium-release channel activity;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0043924//suramin binding;GO:0044325//transmembrane transporter binding;GO:0048763//calcium-induced calcium release activity;GO:0097159//organic cyclic compound binding	GO:0001666//response to hypoxia;GO:0002027//regulation of heart rate;GO:0003143//embryonic heart tube morphogenesis;GO:0003220//left ventricular cardiac muscle tissue morphogenesis;GO:0003300//cardiac muscle hypertrophy;GO:0005513//detection of calcium ion;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0010460//positive regulation of heart rate;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014850//response to muscle activity;GO:0019722//calcium-mediated signaling;GO:0031000//response to caffeine;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0035994//response to muscle stretch;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051284//positive regulation of sequestering of calcium ion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051775//response to redox state;GO:0055085//transmembrane transport;GO:0055117//regulation of cardiac muscle contraction;GO:0060048//cardiac muscle contraction;GO:0060401//cytosolic calcium ion transport;GO:0060402//calcium ion transport into cytosol;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:0071313//cellular response to caffeine;GO:0071872//cellular response to epinephrine stimulus;GO:0072599//establishment of protein localization to endoplasmic reticulum;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086029//Purkinje myocyte to ventricular cardiac muscle cell signaling;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0097050//type B pancreatic cell apoptotic process;GO:0098735//positive regulation of the force of heart contraction;GO:0098904//regulation of AV node cell action potential;GO:0098907//regulation of SA node cell action potential;GO:0098910//regulation of atrial cardiac muscle cell action potential;GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:1901896//positive regulation of ATPase-coupled calcium transmembrane transporter activity	--
ENSG00000198633	0	0	0	0	0	0.025	0	0	0	0	0	2	ZNF534	zinc finger protein 534 [Source:HGNC Symbol;Acc:HGNC:26337]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000198642	13.414	13.796	12.305	10.829	11.005	11.209	1597	1651	1082	955	1107	971	KLHL9	kelch like family member 9 [Source:HGNC Symbol;Acc:HGNC:18732]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10447	GO:0005829//cytosol;GO:0030496//midbody;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0032465//regulation of cytokinesis;GO:0051301//cell division	--
ENSG00000198643	0	0	0	0	0	0	0	0	0	0	0	0	FAM3D	FAM3 metabolism regulating signaling molecule D [Source:HGNC Symbol;Acc:HGNC:18665]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity	GO:0007165//signal transduction;GO:0046676//negative regulation of insulin secretion;GO:0070093//negative regulation of glucagon secretion	--
ENSG00000198646	11.521	12.699	13.121	10.601	11.571	12.893	1635	1727	1349	1136	1362	1341	NCOA6	nuclear receptor coactivator 6 [Source:HGNC Symbol;Acc:HGNC:15936]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0035097//histone methyltransferase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044666//MLL3/4 complex	GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030331//estrogen receptor binding;GO:0030374//nuclear receptor coactivator activity;GO:0046965//retinoid X receptor binding;GO:0046966//thyroid hormone receptor binding	"GO:0006352//DNA-templated transcription, initiation;GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0007507//heart development;GO:0009725//response to hormone;GO:0030099//myeloid cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051568//histone H3-K4 methylation"	--
ENSG00000198648	24.106	23.85	21.307	19.096	20.684	21.284	1636	1627	1068	960	1186	1051	STK39	serine/threonine kinase 39 [Source:HGNC Symbol;Acc:HGNC:17717]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008217//regulation of blood pressure;GO:0010820//positive regulation of T cell chemotaxis;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0035556//intracellular signal transduction;GO:0036438//maintenance of lens transparency;GO:0038146//chemokine (C-X-C motif) ligand 12 signaling pathway;GO:0043268//positive regulation of potassium ion transport;GO:0046777//protein autophosphorylation;GO:0050727//regulation of inflammatory response;GO:0050801//ion homeostasis;GO:0071476//cellular hypotonic response;GO:0090188//negative regulation of pancreatic juice secretion;GO:1900745//positive regulation of p38MAPK cascade;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1905408//negative regulation of creatine transmembrane transporter activity;GO:1990869//cellular response to chemokine;GO:2000650//negative regulation of sodium ion transmembrane transporter activity	--
ENSG00000198650	0.086	0.012	0.083	0.033	0.087	0	7	1	5	2	6	0	TAT	tyrosine aminotransferase [Source:HGNC Symbol;Acc:HGNC:11573]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins;Amino acid metabolism	"ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00350//Tyrosine metabolism;ko00360//Phenylalanine metabolism;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis;ko00400//Phenylalanine, tyrosine and tryptophan biosynthesis"	K00815;K00815;K00815;K00815;K00815;K00815	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0004838//L-tyrosine:2-oxoglutarate aminotransferase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding	GO:0006103//2-oxoglutarate metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0006536//glutamate metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0006572//tyrosine catabolic process;GO:0006979//response to oxidative stress;GO:0009058//biosynthetic process;GO:0009072//aromatic amino acid family metabolic process;GO:0009074//aromatic amino acid family catabolic process;GO:0014070//response to organic cyclic compound;GO:0046689//response to mercury ion;GO:0051384//response to glucocorticoid;GO:0071548//response to dexamethasone	--
ENSG00000198663	32.522	31.232	29.31	28.677	28.86	30.107	3269	3319	2313	2288	2731	2363	C6orf89	chromosome 6 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:21114]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody	GO:0005515//protein binding	GO:0042060//wound healing;GO:0045787//positive regulation of cell cycle;GO:0050673//epithelial cell proliferation;GO:1901727//positive regulation of histone deacetylase activity	--
ENSG00000198668	213.556	203.529	213.051	205.768	207.119	228.054	8653	8301	6790	6496	7353	7043	CALM1	calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	GO:0000922//spindle pole;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0034704//calcium channel complex;GO:0043209//myelin sheath;GO:1902494//catalytic complex	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008179//adenylate cyclase binding;GO:0010856//adenylate cyclase activator activity;GO:0016301//kinase activity;GO:0019855//calcium channel inhibitor activity;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding;GO:0030234//enzyme regulator activity;GO:0031432//titin binding;GO:0031997//N-terminal myristoylation domain binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0072542//protein phosphatase activator activity;GO:0097718//disordered domain specific binding	GO:0000086//G2/M transition of mitotic cell cycle;GO:0002027//regulation of heart rate;GO:0005513//detection of calcium ion;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0016240//autophagosome membrane docking;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0021762//substantia nigra development;GO:0031279//regulation of cyclase activity;GO:0031954//positive regulation of protein autophosphorylation;GO:0032465//regulation of cytokinesis;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0043388//positive regulation of DNA binding;GO:0050848//regulation of calcium-mediated signaling;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051592//response to calcium ion;GO:0055117//regulation of cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0098901//regulation of cardiac muscle cell action potential;GO:0140056//organelle localization by membrane tethering;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:1901842//negative regulation of high voltage-gated calcium channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:1905913//negative regulation of calcium ion export across plasma membrane;GO:1990456//mitochondrion-endoplasmic reticulum membrane tethering	--
ENSG00000198670	0.032	0.015	0	0	0.186	0.036	3	2	0	0	7	1	LPA	lipoprotein(a) [Source:HGNC Symbol;Acc:HGNC:6667]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K09644	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0019897//extrinsic component of plasma membrane;GO:0034358//plasma lipoprotein particle	GO:0001968//fibronectin binding;GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0004866//endopeptidase inhibitor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0034185//apolipoprotein binding	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0008015//blood circulation;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000198673	0.096	0.23	0.052	0	0.1	0.106	5	12	2	0	1	4	TAFA2	TAFA chemokine like family member 2 [Source:HGNC Symbol;Acc:HGNC:21589]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0048018//receptor ligand activity	GO:0007165//signal transduction;GO:0007613//memory;GO:0008542//visual learning	--
ENSG00000198674	0	0	0	0	0	0	0	0	0	0	0	0	OR10G6	olfactory receptor family 10 subfamily G member 6 [Source:HGNC Symbol;Acc:HGNC:14836]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198677	15.009	10.063	10.102	6.374	7.259	8.08	1741	1192	885	556	724	695	TTC37	tetratricopeptide repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:23639]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12600	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0055087//Ski complex	GO:0005515//protein binding	"GO:0006401//RNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'"	--
ENSG00000198678	0	0	0	0	0	0	0	0	0	0	0	0	OR5BS1P	olfactory receptor family 5 subfamily BS member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:19627]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198680	9.44	10.496	10.083	11.862	10.052	13.019	289	323	228	269	260	290	TUSC1	tumor suppressor candidate 1 [Source:HGNC Symbol;Acc:HGNC:31010]	-	-	-	-	-	-	-	--
ENSG00000198681	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA1	MAGE family member A1 [Source:HGNC Symbol;Acc:HGNC:6796]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0045746//negative regulation of Notch signaling pathway	--
ENSG00000198682	0.94	1.057	0.76	0.723	0.65	0.789	77	87	46	42	45	47	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2 [Source:HGNC Symbol;Acc:HGNC:8604]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of other amino acids;Energy metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00450//Selenocompound metabolism;ko00920//Sulfur metabolism	K13811;K13811;K13811;K13811	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004020//adenylylsulfate kinase activity;GO:0004781//sulfate adenylyltransferase (ATP) activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity	GO:0000103//sulfate assimilation;GO:0007596//blood coagulation;GO:0008152//metabolic process;GO:0016310//phosphorylation;GO:0042445//hormone metabolic process;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0060348//bone development	--
ENSG00000198689	11.837	10.092	11.29	10.591	10.187	10.315	1061	990	749	690	765	714	SLC9A6	solute carrier family 9 member A6 [Source:HGNC Symbol;Acc:HGNC:11079]	Organismal Systems	Circulatory system	ko04260//Cardiac muscle contraction	K12041	GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043679//axon terminus;GO:0044308//axonal spine;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0015297//antiporter activity;GO:0015299//solute:proton antiporter activity;GO:0015385//sodium:proton antiporter activity;GO:0015386//potassium:proton antiporter activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0006885//regulation of pH;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0035725//sodium ion transmembrane transport;GO:0048675//axon extension;GO:0048812//neuron projection morphogenesis;GO:0050808//synapse organization;GO:0051386//regulation of neurotrophin TRK receptor signaling pathway;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0060996//dendritic spine development;GO:0071805//potassium ion transmembrane transport;GO:0097484//dendrite extension;GO:0098656//anion transmembrane transport;GO:0098719//sodium ion import across plasma membrane;GO:1902600//proton transmembrane transport	--
ENSG00000198690	9.651	8.456	8.525	8.604	9.48	8.825	859.01	779.52	583.37	578.48	739.92	583.11	FAN1	FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K15363	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045171//intercellular bridge	"GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004527//exonuclease activity;GO:0004528//phosphodiesterase I activity;GO:0005515//protein binding;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0017108//5'-flap endonuclease activity;GO:0046872//metal ion binding;GO:0070336//flap-structured DNA binding;GO:0140036//ubiquitin-dependent protein binding"	"GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0033683//nucleotide-excision repair, DNA incision;GO:0036297//interstrand cross-link repair;GO:0090304//nucleic acid metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000198691	1.151	1.359	1.337	0.941	1.269	1.166	175	204	144	106	163	129	ABCA4	ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34]	Environmental Information Processing	Membrane transport	ko02010//ABC transporters	K05644	GO:0001750//photoreceptor outer segment;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0097381//photoreceptor disc membrane;GO:0120202//rod photoreceptor disc membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005215//transporter activity;GO:0005319//lipid transporter activity;GO:0005501//retinoid binding;GO:0005502//11-cis retinal binding;GO:0005503//all-trans retinal binding;GO:0005524//ATP binding;GO:0005548//phospholipid transporter activity;GO:0016887//ATP hydrolysis activity;GO:0034632//retinol transmembrane transporter activity;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0090555//phosphatidylethanolamine flippase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140327//flippase activity;GO:0140347//N-retinylidene-phosphatidylethanolamine flippase activity;GO:0140359//ABC-type transporter activity	"GO:0001523//retinoid metabolic process;GO:0006649//phospholipid transfer to membrane;GO:0006869//lipid transport;GO:0007601//visual perception;GO:0007603//phototransduction, visible light;GO:0034633//retinol transport;GO:0042574//retinal metabolic process;GO:0045332//phospholipid translocation;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0055085//transmembrane transport"	--
ENSG00000198692	8.209	8.363	9.311	8.774	6.156	9.254	228	223	191	164	135	187	EIF1AY	eukaryotic translation initiation factor 1A Y-linked [Source:HGNC Symbol;Acc:HGNC:3252]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000198695	3794.005	4386.357	4378.919	5092.219	4883.332	3901.545	41315	48011	35218	41075	44927	30913	MT-ND6	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 [Source:HGNC Symbol;Acc:HGNC:7462]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03884;K03884;K03884;K03884;K03884;K03884;K03884;K03884;K03884;K03884;K03884;K03884	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0035094//response to nicotine;GO:0042220//response to cocaine;GO:0042542//response to hydrogen peroxide;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000198700	10.571	10.483	10.55	9.541	9.377	9.879	2503	2495	1845	1523	1876	1702	IPO9	importin 9 [Source:HGNC Symbol;Acc:HGNC:19425]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K20224	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042393//histone binding;GO:0061608//nuclear import signal receptor activity	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport	--
ENSG00000198704	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000198707	0.205	1.158	0.453	0.408	0.236	0.295	28.25	34.24	19.11	19.07	27	17	CEP290	centrosomal protein 290 [Source:HGNC Symbol;Acc:HGNC:29021]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0032391//photoreceptor connecting cilium;GO:0032991//protein-containing complex;GO:0034451//centriolar satellite;GO:0035580//specific granule lumen;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0001822//kidney development;GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0030902//hindbrain development;GO:0030916//otic vesicle formation;GO:0042462//eye photoreceptor cell development;GO:0043010//camera-type eye development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048793//pronephros development;GO:0060271//cilium assembly;GO:0070201//regulation of establishment of protein localization;GO:0090316//positive regulation of intracellular protein transport;GO:0097711//ciliary basal body-plasma membrane docking;GO:1905349//ciliary transition zone assembly;GO:1905515//non-motile cilium assembly"	--
ENSG00000198712	10997.267	11824.794	11753.045	14463.976	13768.379	12853.862	156024	168627	123153	152004	165033	132689	MT-CO2	mitochondrially encoded cytochrome c oxidase II [Source:HGNC Symbol;Acc:HGNC:7421]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261;K02261	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV;GO:0070469//respirasome	GO:0004129//cytochrome-c oxidase activity;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	"GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0007595//lactation;GO:0009409//response to cold;GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:0010940//positive regulation of necrotic cell death;GO:0022900//electron transport chain;GO:0042773//ATP synthesis coupled electron transport;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000198715	59.477	63.309	61.899	71.976	66.199	67.725	1900	2029	1461	1716	1818	1542	GLMP	glycosylated lysosomal membrane protein [Source:HGNC Symbol;Acc:HGNC:29436]	-	-	-	-	GO:0005634//nucleus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0061462//protein localization to lysosome	NCU-G1
ENSG00000198718	6.298	5.214	5.117	4.869	6.3	5.253	708	551	404	315	441	368	TOGARAM1	TOG array regulator of axonemal microtubules 1 [Source:HGNC Symbol;Acc:HGNC:19959]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005881//cytoplasmic microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0030030//cell projection organization;GO:0031116//positive regulation of microtubule polymerization;GO:0035082//axoneme assembly;GO:0060271//cilium assembly;GO:0090307//mitotic spindle assembly;GO:1905515//non-motile cilium assembly	--
ENSG00000198719	0.651	0.736	0.449	0.62	0.468	0.824	51	58	26	36	31	47	DLL1	delta like canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2908]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Cancer: overview;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Immune system;Signal transduction	ko05200//Pathways in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05224//Breast cancer;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway	K06051;K06051;K06051;K06051;K06051;K06051	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030957//Tat protein binding;GO:0097110//scaffold protein binding	GO:0001709//cell fate determination;GO:0001756//somitogenesis;GO:0001757//somite specification;GO:0001947//heart looping;GO:0002315//marginal zone B cell differentiation;GO:0003323//type B pancreatic cell development;GO:0007154//cell communication;GO:0007219//Notch signaling pathway;GO:0007267//cell-cell signaling;GO:0007275//multicellular organism development;GO:0007368//determination of left/right symmetry;GO:0007386//compartment pattern specification;GO:0008217//regulation of blood pressure;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009954//proximal/distal pattern formation;GO:0010628//positive regulation of gene expression;GO:0014002//astrocyte development;GO:0014807//regulation of somitogenesis;GO:0021510//spinal cord development;GO:0021688//cerebellar molecular layer formation;GO:0021693//cerebellar Purkinje cell layer structural organization;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030155//regulation of cell adhesion;GO:0030857//negative regulation of epithelial cell differentiation;GO:0032502//developmental process;GO:0032693//negative regulation of interleukin-10 production;GO:0034351//negative regulation of glial cell apoptotic process;GO:0035265//organ growth;GO:0040008//regulation of growth;GO:0045596//negative regulation of cell differentiation;GO:0045605//negative regulation of epidermal cell differentiation;GO:0045608//negative regulation of inner ear auditory receptor cell differentiation;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045747//positive regulation of Notch signaling pathway;GO:0045807//positive regulation of endocytosis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046331//lateral inhibition;GO:0048630//skeletal muscle tissue growth;GO:0048631//regulation of skeletal muscle tissue growth;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0048665//neuron fate specification;GO:0048839//inner ear development;GO:0050767//regulation of neurogenesis;GO:0051302//regulation of cell division;GO:0060041//retina development in camera-type eye;GO:0060042//retina morphogenesis in camera-type eye;GO:0060853//Notch signaling pathway involved in arterial endothelial cell fate commitment;GO:0070986//left/right axis specification;GO:0072006//nephron development;GO:0072014//proximal tubule development;GO:0072070//loop of Henle development;GO:0072583//clathrin-dependent endocytosis;GO:0097009//energy homeostasis;GO:0097102//endothelial tip cell fate specification;GO:0097150//neuronal stem cell population maintenance;GO:0098773//skin epidermis development;GO:1900746//regulation of vascular endothelial growth factor signaling pathway;GO:1903672//positive regulation of sprouting angiogenesis;GO:2000726//negative regulation of cardiac muscle cell differentiation	--
ENSG00000198720	4.082	3.406	4.938	6.253	7.263	5.793	237	237	230	276	285	292	ANKRD13B	ankyrin repeat domain 13B [Source:HGNC Symbol;Acc:HGNC:26363]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0140036//ubiquitin-dependent protein binding	GO:0002091//negative regulation of receptor internalization	--
ENSG00000198721	27.667	29.643	25.275	24.432	22.922	26.306	789	848	533	516	553	547	ECI2	enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601]	Cellular Processes;Metabolism	Transport and catabolism;Lipid metabolism	ko04146//Peroxisome;ko00071//Fatty acid degradation	K13239;K13239	GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0000062//fatty-acyl-CoA binding;GO:0003824//catalytic activity;GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation	--
ENSG00000198722	22.958	22.769	23.815	24.429	23.83	23.91	3023	3011	2316	2336	2651	2286	UNC13B	unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15293	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction;GO:0042734//presynaptic membrane;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0048786//presynaptic active zone;GO:0098793//presynapse;GO:0098831//presynaptic active zone cytoplasmic component	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0017075//syntaxin-1 binding;GO:0019992//diacylglycerol binding;GO:0030742//GTP-dependent protein binding;GO:0031267//small GTPase binding;GO:0046872//metal ion binding	"GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission;GO:0007528//neuromuscular junction development;GO:0010808//positive regulation of synaptic vesicle priming;GO:0016081//synaptic vesicle docking;GO:0016082//synaptic vesicle priming;GO:0016188//synaptic vesicle maturation;GO:0035249//synaptic transmission, glutamatergic;GO:0043065//positive regulation of apoptotic process;GO:0050714//positive regulation of protein secretion;GO:0060478//acrosomal vesicle exocytosis;GO:0061789//dense core granule priming;GO:0071333//cellular response to glucose stimulus;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:0099011//neuronal dense core vesicle exocytosis;GO:0099525//presynaptic dense core vesicle exocytosis"	--
ENSG00000198723	0.029	0.122	0	0	0	0	1	2	0	0	0	0	TEX45	testis expressed 45 [Source:HGNC Symbol;Acc:HGNC:24745]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000198727	4872.771	5029.703	5815.106	7014.191	6331.79	6815.658	115322	119648	101644	122963	126603	117365	MT-CYB	mitochondrially encoded cytochrome b [Source:HGNC Symbol;Acc:HGNC:7427]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412;K00412	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0045275//respiratory chain complex III;GO:0070469//respirasome	GO:0008121//ubiquinol-cytochrome-c reductase activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0022904//respiratory electron transport chain;GO:0045333//cellular respiration;GO:1902600//proton transmembrane transport"	--
ENSG00000198728	49.139	53.965	55.677	48.43	51.755	49.578	2825	3075	2332	2048	2528	2100	LDB1	LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15617	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0031252//cell leading edge;GO:0032991//protein-containing complex;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990907//beta-catenin-TCF complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030274//LIM domain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000972//transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0001702//gastrulation with mouth forming second;GO:0001942//hair follicle development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0009948//anterior/posterior axis specification;GO:0010669//epithelial structure maintenance;GO:0016055//Wnt signaling pathway;GO:0021549//cerebellum development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0022607//cellular component assembly;GO:0030182//neuron differentiation;GO:0030334//regulation of cell migration;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0035019//somatic stem cell population maintenance;GO:0043549//regulation of kinase activity;GO:0043973//histone H3-K4 acetylation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045785//positive regulation of cell adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048382//mesendoderm development;GO:0051893//regulation of focal adhesion assembly;GO:0060322//head development"	--
ENSG00000198729	0.326	0.259	0.029	0.176	0.309	0.269	15	12	1	6	12	9	PPP1R14C	protein phosphatase 1 regulatory inhibitor subunit 14C [Source:HGNC Symbol;Acc:HGNC:14952]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity	GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity	--
ENSG00000198730	12.804	13.182	11.111	8.448	9.555	10.023	1150	1190	737	562	725	655	CTR9	"CTR9 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:16850]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016593//Cdc73/Paf1 complex;GO:0016607//nuclear speck;GO:0035327//transcriptionally active chromatin;GO:0110165//cellular anatomical entity	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0042169//SH2 domain binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001711//endodermal cell fate commitment;GO:0001826//inner cell mass cell differentiation;GO:0001829//trophectodermal cell differentiation;GO:0001832//blastocyst growth;GO:0001835//blastocyst hatching;GO:0006355//regulation of transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0010390//histone monoubiquitination;GO:0016055//Wnt signaling pathway;GO:0016570//histone modification;GO:0019827//stem cell population maintenance;GO:0033523//histone H2B ubiquitination;GO:0045638//negative regulation of myeloid cell differentiation;GO:0051569//regulation of histone H3-K4 methylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0070102//interleukin-6-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0080182//histone H3-K4 trimethylation;GO:1900364//negative regulation of mRNA polyadenylation;GO:2000653//regulation of genetic imprinting;GO:2001162//positive regulation of histone H3-K79 methylation;GO:2001168//positive regulation of histone H2B ubiquitination"	--
ENSG00000198732	0.736	0.862	0.64	1.683	1.944	1.713	56	66	36	95	125	95	SMOC1	SPARC related modular calcium binding 1 [Source:HGNC Symbol;Acc:HGNC:20318]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0046872//metal ion binding;GO:0050840//extracellular matrix binding	GO:0001654//eye development;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0045667//regulation of osteoblast differentiation;GO:0060173//limb development	--
ENSG00000198734	0.034	0.021	0.046	0.018	0.049	0.009	5	4	5	2	6	1	F5	coagulation factor V [Source:HGNC Symbol;Acc:HGNC:3542]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K03902	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:1903561//extracellular vesicle	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0008015//blood circulation;GO:0032571//response to vitamin K	--
ENSG00000198736	10.835	11.872	13.188	15.276	13.227	10.585	287	303	258	270	296	204	MSRB1	methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0046872//metal ion binding;GO:0070191//methionine-R-sulfoxide reductase activity	GO:0002376//immune system process;GO:0030041//actin filament polymerization;GO:0030091//protein repair;GO:0045087//innate immune response	--
ENSG00000198739	0	0	0.011	0.011	0.009	0	0	0	1	1	1	0	LRRTM3	leucine rich repeat transmembrane neuronal 3 [Source:HGNC Symbol;Acc:HGNC:19410]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly;GO:0099054//presynapse assembly;GO:1902004//positive regulation of amyloid-beta formation	--
ENSG00000198740	4.39	3.549	3.976	2.896	3.109	3.249	755	572	511	345	473	388	ZNF652	zinc finger protein 652 [Source:HGNC Symbol;Acc:HGNC:29147]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000198742	8.879	8.522	9.165	8.348	9.766	9.948	1043.92	1007	796	727	970	851	SMURF1	SMAD specific E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:16807]	Cellular Processes;Genetic Information Processing;Environmental Information Processing;Environmental Information Processing	"Transport and catabolism;Folding, sorting and degradation;Signal transduction;Signal transduction"	ko04144//Endocytosis;ko04120//Ubiquitin mediated proteolysis;ko04350//TGF-beta signaling pathway;ko04340//Hedgehog signaling pathway	K04678;K04678;K04678;K04678	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0070062//extracellular exosome	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0016740//transferase activity;GO:0048185//activin binding;GO:0061630//ubiquitin protein ligase activity;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding	"GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006611//protein export from nucleus;GO:0007398//ectoderm development;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0030509//BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0032801//receptor catabolic process;GO:0034394//protein localization to cell surface;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061736//engulfment of target by autophagosome;GO:0061753//substrate localization to autophagosome;GO:0071211//protein targeting to vacuole involved in autophagy;GO:0072659//protein localization to plasma membrane;GO:1903861//positive regulation of dendrite extension;GO:2000060//positive regulation of ubiquitin-dependent protein catabolic process"	--
ENSG00000198743	41.858	29.743	35.051	20.954	22.707	39.187	10041.92	7172	6210.48	3723.57	4602.22	6840.24	SLC5A3	solute carrier family 5 member 3 [Source:HGNC Symbol;Acc:HGNC:11038]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005365//myo-inositol transmembrane transporter activity;GO:0005367//myo-inositol:sodium symporter activity;GO:0005412//glucose:sodium symporter activity;GO:0015146//pentose transmembrane transporter activity;GO:0015150//fucose transmembrane transporter activity;GO:0015166//polyol transmembrane transporter activity;GO:0015293//symporter activity;GO:0015459//potassium channel regulator activity;GO:0022857//transmembrane transporter activity;GO:0044325//transmembrane transporter binding	GO:0006020//inositol metabolic process;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007422//peripheral nervous system development;GO:0015750//pentose transmembrane transport;GO:0015756//fucose transmembrane transport;GO:0015791//polyol transport;GO:0015798//myo-inositol transport;GO:0032409//regulation of transporter activity;GO:0043085//positive regulation of catalytic activity;GO:0043576//regulation of respiratory gaseous exchange;GO:0055085//transmembrane transport;GO:0150104//transport across blood-brain barrier;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904659//glucose transmembrane transport;GO:1904679//myo-inositol import across plasma membrane;GO:1905477//positive regulation of protein localization to membrane	--
ENSG00000198746	7.101	7.29	8.916	6.34	6.445	6.798	313	322.96	226	207	240	218	GPATCH3	G-patch domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25720]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0005515//protein binding	"GO:0032480//negative regulation of type I interferon production;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000198752	32.175	31.422	31.096	29.486	32.242	32.873	3940	3878	2788	2743	3373	2849	CDC42BPB	CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0042641//actomyosin;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0018107//peptidyl-threonine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization	--
ENSG00000198753	12.796	13.199	15.482	17.263	19.355	19.102	1639.42	1703	1466.85	1523	1973	1749	PLXNB3	plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06821	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity;GO:0019904//protein domain specific binding;GO:0051022//Rho GDP-dissociation inhibitor binding;GO:0098632//cell-cell adhesion mediator activity	GO:0001938//positive regulation of endothelial cell proliferation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008360//regulation of cell shape;GO:0010593//negative regulation of lamellipodium assembly;GO:0010976//positive regulation of neuron projection development;GO:0030334//regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0034260//negative regulation of GTPase activity;GO:0043087//regulation of GTPase activity;GO:0050772//positive regulation of axonogenesis;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000198754	0.264	0.053	0	0.071	0	0.073	10	2	0	2	0	2	OXCT2	3-oxoacid CoA-transferase 2 [Source:HGNC Symbol;Acc:HGNC:18606]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00650//Butanoate metabolism"	K01027;K01027;K01027	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0031514//motile cilium	GO:0008260//3-oxoacid CoA-transferase activity;GO:0008410//CoA-transferase activity;GO:0016740//transferase activity	GO:0046950//cellular ketone body metabolic process;GO:0046952//ketone body catabolic process	--
ENSG00000198755	414.43	427.942	411.21	456.147	388.645	352.805	6172	6406	4523	5032	4890	3823	RPL10A	ribosomal protein L10a [Source:HGNC Symbol;Acc:HGNC:10299]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02865;K02865	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015934//large ribosomal subunit;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0000470//maturation of LSU-rRNA;GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000198756	6.674	7.141	6.799	8.204	9.72	8.341	700	758	539	642	843	642	COLGALT2	collagen beta(1-O)galactosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16790]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation;ko00514//Other types of O-glycan biosynthesis	K11703;K11703;K11703	GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0050211//procollagen galactosyltransferase activity	GO:0030199//collagen fibril organization	--
ENSG00000198758	0	0	0	0	0	0	0	0	0	0	0	0	EPS8L3	EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0032587//ruffle membrane	GO:0003779//actin binding;GO:0005515//protein binding	GO:0007266//Rho protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0042634//regulation of hair cycle;GO:1900029//positive regulation of ruffle assembly	--
ENSG00000198759	0.724	0.62	0.489	0.516	0.335	0.417	36	31	18	19	14	15	EGFL6	EGF like domain multiple 6 [Source:HGNC Symbol;Acc:HGNC:3235]	-	-	-	-	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031012//extracellular matrix	GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization	--
ENSG00000198763	4269.806	4698.248	5119.374	6240.84	5716.335	5466.874	92284	102066	81719	99913	104380	85971	MT-ND2	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 [Source:HGNC Symbol;Acc:HGNC:7456]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03879;K03879;K03879;K03879;K03879;K03879;K03879;K03879;K03879;K03879;K03879;K03879	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity;GO:0019901//protein kinase binding;GO:0035255//ionotropic glutamate receptor binding	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0072593//reactive oxygen species metabolic process"	--
ENSG00000198765	0	0	0.021	0	0	0	0	0	1	0	0	0	SYCP1	synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000801//central element;GO:0000802//transverse filament;GO:0001673//male germ cell nucleus;GO:0005634//nucleus;GO:0005694//chromosome"	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding	GO:0000711//meiotic DNA repair synthesis;GO:0007049//cell cycle;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007283//spermatogenesis;GO:0032880//regulation of protein localization;GO:0035092//sperm chromatin condensation;GO:0051026//chiasma assembly;GO:0051289//protein homotetramerization;GO:0051301//cell division;GO:0051321//meiotic cell cycle;GO:0051878//lateral element assembly	--
ENSG00000198768	0	0.173	0.034	0	0.015	0.068	0	14	2	0	1	4	APCDD1L	APC down-regulated 1 like [Source:HGNC Symbol;Acc:HGNC:26892]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017147//Wnt-protein binding	GO:0030178//negative regulation of Wnt signaling pathway	--
ENSG00000198771	0.027	0	0	0	0.052	0	3	0	0	0	5	0	RCSD1	RCSD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28310]	-	-	-	-	GO:0005884//actin filament	GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0071474//cellular hyperosmotic response	--
ENSG00000198774	0.953	0.861	0.556	0.519	0.569	0.877	109	99	47	44	55	73	RASSF9	Ras association domain family member 9 [Source:HGNC Symbol;Acc:HGNC:15739]	-	-	-	-	GO:0005768//endosome;GO:0005829//cytosol;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0055037//recycling endosome;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0016197//endosomal transport;GO:0046907//intracellular transport	--
ENSG00000198780	2.56	1.404	2.599	1.053	1.817	1.585	244.53	170.55	144.52	99.13	149.34	146.49	FAM169A	family with sequence similarity 169 member A [Source:HGNC Symbol;Acc:HGNC:29138]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005637//nuclear inner membrane;GO:0016020//membrane	GO:0005515//protein binding	-	--
ENSG00000198783	4.287	4.394	4.463	4.566	4.666	5.033	199	205	153	157	183	170	ZNF830	zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005694//chromosome;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0001541//ovarian follicle development;GO:0001546//preantral ovarian follicle growth;GO:0001832//blastocyst growth;GO:0006397//mRNA processing;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0033260//nuclear DNA replication;GO:0033314//mitotic DNA replication checkpoint signaling;GO:0043066//negative regulation of apoptotic process;GO:0044773//mitotic DNA damage checkpoint signaling;GO:0048478//replication fork protection;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0060729//intestinal epithelial structure maintenance	--
ENSG00000198785	0.092	0.098	0.15	0.241	0.284	0.279	15	16	18	29	39	33	GRIN3A	glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signaling molecules and interaction;Neurodegenerative disease;Signal transduction;Substance dependence;Neurodegenerative disease;Nervous system;Substance dependence;Substance dependence;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko05020//Prion disease;ko04024//cAMP signaling pathway;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04724//Glutamatergic synapse;ko05031//Amphetamine addiction;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05213;K05213;K05213;K05213;K05213;K05213;K05213;K05213;K05213	GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015276//ligand-gated ion channel activity;GO:0016594//glycine binding;GO:0038023//signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0042802//identical protein binding;GO:0051721//protein phosphatase 2A binding;GO:1904315//transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0016358//dendrite development;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0045471//response to ethanol;GO:0048511//rhythmic process;GO:0060078//regulation of postsynaptic membrane potential;GO:0060134//prepulse inhibition;GO:0061000//negative regulation of dendritic spine development;GO:0070588//calcium ion transmembrane transport;GO:2000300//regulation of synaptic vesicle exocytosis	--
ENSG00000198786	5624.128	7041.057	6915.276	7904.882	8091.766	6267.36	211380	265995	191958	220072	256941	171391	MT-ND5	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 [Source:HGNC Symbol;Acc:HGNC:7461]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03883;K03883;K03883;K03883;K03883;K03883;K03883;K03883;K03883;K03883;K03883;K03883	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0070469//respirasome	GO:0003954//NADH dehydrogenase activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0001666//response to hypoxia;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0010243//response to organonitrogen compound;GO:0015990//electron transport coupled proton transport;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042542//response to hydrogen peroxide;GO:0042773//ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000198788	0	0	0	0	0	0	0	0	0	0	0	0	MUC2	"mucin 2, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7512]"	Human Diseases;Human Diseases	Infectious disease: parasitic;Cancer: specific types	ko05146//Amoebiasis;ko05226//Gastric cancer	K10955;K10955	GO:0005576//extracellular region;GO:0070701//mucus layer;GO:0110165//cellular anatomical entity	GO:0005102//signaling receptor binding;GO:0005515//protein binding	-	--
ENSG00000198791	47.267	37.972	36.074	35.839	31.164	30.803	2015	1848	1267	1179	1285	1164	CNOT7	CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12581	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0030014//CCR4-NOT complex;GO:0030015//CCR4-NOT core complex	GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0004532//exoribonuclease activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006402//mRNA catabolic process;GO:0006417//regulation of translation;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0031047//gene silencing by RNA;GO:0033962//P-body assembly;GO:0035195//gene silencing by miRNA;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0043928//exonucleolytic catabolism of deadenylated mRNA;GO:0045070//positive regulation of viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061014//positive regulation of mRNA catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"	--
ENSG00000198792	49.219	49.08	53.02	63.13	67.19	66.011	3495	3568	2873	3350	4115	3472	TMEM184B	transmembrane protein 184B [Source:HGNC Symbol;Acc:HGNC:1310]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000198793	18.464	19.051	18.638	15.362	17.701	17.836	3225	3370	2490	2032	2626	2290	MTOR	mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes	Infectious disease: viral;Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Immune system;Infectious disease: bacterial;Environmental adaptation;Infectious disease: viral;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Infectious disease: viral;Cancer: overview;Signal transduction;Cancer: specific types;Signal transduction;Cell growth and death;Transport and catabolism;Cancer: specific types;Cancer: specific types;Neurodegenerative disease;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Cancer: overview;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Aging;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Endocrine system;Aging;Endocrine and metabolic disease;Transport and catabolism	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05016//Huntington disease;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko04140//Autophagy - animal;ko05224//Breast cancer;ko05226//Gastric cancer;ko05017//Spinocerebellar ataxia;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04152//AMPK signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko04659//Th17 cell differentiation;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05214//Glioma;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04920//Adipocytokine signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04930//Type II diabetes mellitus;ko04136//Autophagy - other"	K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203;K07203	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016605//PML body;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0001002//RNA polymerase III type 1 promoter sequence-specific DNA binding;GO:0001003//RNA polymerase III type 2 promoter sequence-specific DNA binding;GO:0001006//RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0001156//TFIIIC-class transcription factor complex binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043022//ribosome binding;GO:0044877//protein-containing complex binding;GO:0051219//phosphoprotein binding;GO:0106310//protein serine kinase activity	"GO:0001558//regulation of cell growth;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002296//T-helper 1 cell lineage commitment;GO:0003007//heart morphogenesis;GO:0003179//heart valve morphogenesis;GO:0006112//energy reserve metabolic process;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0007010//cytoskeleton organization;GO:0007040//lysosome organization;GO:0007281//germ cell development;GO:0007584//response to nutrient;GO:0008361//regulation of cell size;GO:0009267//cellular response to starvation;GO:0009408//response to heat;GO:0009791//post-embryonic development;GO:0010506//regulation of autophagy;GO:0010507//negative regulation of autophagy;GO:0010592//positive regulation of lamellipodium assembly;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010831//positive regulation of myotube differentiation;GO:0016241//regulation of macroautophagy;GO:0016242//negative regulation of macroautophagy;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0019228//neuronal action potential;GO:0030030//cell projection organization;GO:0030163//protein catabolic process;GO:0030307//positive regulation of cell growth;GO:0030838//positive regulation of actin filament polymerization;GO:0031529//ruffle organization;GO:0031641//regulation of myelination;GO:0031667//response to nutrient levels;GO:0031669//cellular response to nutrient levels;GO:0031929//TOR signaling;GO:0032148//activation of protein kinase B activity;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032868//response to insulin;GO:0032956//regulation of actin cytoskeleton organization;GO:0034198//cellular response to amino acid starvation;GO:0035264//multicellular organism growth;GO:0038202//TORC1 signaling;GO:0042221//response to chemical;GO:0042752//regulation of circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0043200//response to amino acid;GO:0043276//anoikis;GO:0044238//primary metabolic process;GO:0045670//regulation of osteoclast differentiation;GO:0045727//positive regulation of translation;GO:0045792//negative regulation of cell size;GO:0045821//positive regulation of glycolytic process;GO:0045859//regulation of protein kinase activity;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0046777//protein autophosphorylation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048266//behavioral response to pain;GO:0048511//rhythmic process;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0048738//cardiac muscle tissue development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050882//voluntary musculoskeletal movement;GO:0051496//positive regulation of stress fiber assembly;GO:0051549//positive regulation of keratinocyte migration;GO:0051647//nucleus localization;GO:0051896//regulation of protein kinase B signaling;GO:0055006//cardiac cell development;GO:0055013//cardiac muscle cell development;GO:0060048//cardiac muscle contraction;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0071230//cellular response to amino acid stimulus;GO:0071233//cellular response to leucine;GO:0071456//cellular response to hypoxia;GO:0071470//cellular response to osmotic stress;GO:0080135//regulation of cellular response to stress;GO:0090559//regulation of membrane permeability;GO:1900034//regulation of cellular response to heat;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1901838//positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:1903691//positive regulation of wound healing, spreading of epidermal cells;GO:1904059//regulation of locomotor rhythm;GO:1904690//positive regulation of cytoplasmic translational initiation;GO:1905857//positive regulation of pentose-phosphate shunt;GO:1990253//cellular response to leucine starvation;GO:2000112//regulation of cellular macromolecule biosynthetic process"	--
ENSG00000198794	19.249	16.85	18.597	19.157	21.568	19.32	882	1043	785	895	945	732	SCAMP5	secretory carrier membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:30386]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032588//trans-Golgi network membrane;GO:0045202//synapse;GO:0055038//recycling endosome membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0044877//protein-containing complex binding	GO:0001819//positive regulation of cytokine production;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0034976//response to endoplasmic reticulum stress;GO:0045806//negative regulation of endocytosis;GO:0045956//positive regulation of calcium ion-dependent exocytosis	--
ENSG00000198795	4.309	7.198	3.215	2.613	2.812	2.94	324	361	215	152	178	166	ZNF521	zinc finger protein 521 [Source:HGNC Symbol;Acc:HGNC:24605]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048663//neuron fate commitment	zf-C2H2
ENSG00000198796	0.998	0.935	0.351	1.111	1.42	0.989	154	145	40	127	185	111	ALPK2	alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:20565]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane	GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0003007//heart morphogenesis;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0006468//protein phosphorylation;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0030010//establishment of cell polarity;GO:0042981//regulation of apoptotic process;GO:0055013//cardiac muscle cell development;GO:1905223//epicardium morphogenesis	--
ENSG00000198797	0.047	0.105	0.175	0.207	0.139	0.356	4	9	11	13	10	22	BRINP2	BMP/retinoic acid inducible neural specific 2 [Source:HGNC Symbol;Acc:HGNC:13746]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0030425//dendrite;GO:0043025//neuronal cell body	-	GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0045666//positive regulation of neuron differentiation;GO:0045786//negative regulation of cell cycle;GO:0045930//negative regulation of mitotic cell cycle;GO:0071300//cellular response to retinoic acid	--
ENSG00000198798	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB3	MAGE family member B3 [Source:HGNC Symbol;Acc:HGNC:6810]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000198799	2.826	2.596	2.54	2.167	2.61	3.088	678	626	450	385	529	539	LRIG2	leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K24609	GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone;GO:0031012//extracellular matrix;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0097708//intracellular vesicle	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0007605//sensory perception of sound;GO:0010640//regulation of platelet-derived growth factor receptor signaling pathway;GO:0010977//negative regulation of neuron projection development;GO:0048679//regulation of axon regeneration;GO:0048681//negative regulation of axon regeneration;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0060384//innervation;GO:2000010//positive regulation of protein localization to cell surface;GO:2001222//regulation of neuron migration	--
ENSG00000198804	15997.577	17397.408	17833.502	22720.648	22890.488	20612.306	511669	559302	421269	538290	618545	479685	MT-CO1	mitochondrially encoded cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:7419]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256;K02256	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV;GO:0070469//respirasome	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0020037//heme binding;GO:0046872//metal ion binding	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0009060//aerobic respiration;GO:0015990//electron transport coupled proton transport;GO:0021549//cerebellum development;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain;GO:0045333//cellular respiration;GO:0046688//response to copper ion;GO:0051602//response to electrical stimulus;GO:1902600//proton transmembrane transport"	--
ENSG00000198805	7.775	9.086	9.73	9.51	8.396	10.688	235	273	203	184	203	230	PNP	purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K03783;K03783;K03783	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0001882//nucleoside binding;GO:0002060//purine nucleobase binding;GO:0003824//catalytic activity;GO:0004731//purine-nucleoside phosphorylase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042301//phosphate ion binding;GO:0042802//identical protein binding;GO:0047975//guanosine phosphorylase activity	GO:0000255//allantoin metabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006148//inosine catabolic process;GO:0006149//deoxyinosine catabolic process;GO:0006157//deoxyadenosine catabolic process;GO:0006166//purine ribonucleoside salvage;GO:0006204//IMP catabolic process;GO:0006738//nicotinamide riboside catabolic process;GO:0006955//immune response;GO:0009116//nucleoside metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0009410//response to xenobiotic stimulus;GO:0032743//positive regulation of interleukin-2 production;GO:0034418//urate biosynthetic process;GO:0042102//positive regulation of T cell proliferation;GO:0042278//purine nucleoside metabolic process;GO:0043101//purine-containing compound salvage;GO:0046059//dAMP catabolic process;GO:0046638//positive regulation of alpha-beta T cell differentiation	--
ENSG00000198807	0.012	0	0.018	0.016	0	0	1	0	1.15	1	0	0	PAX9	paired box 9 [Source:HGNC Symbol;Acc:HGNC:8623]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007492//endoderm development;GO:0009887//animal organ morphogenesis;GO:0042476//odontogenesis;GO:0042481//regulation of odontogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development;GO:0060325//face morphogenesis;GO:0071363//cellular response to growth factor stimulus"	PAX
ENSG00000198812	0	0	0	0	0	0	0	0	0	0	0	0	LRRC10	leucine rich repeat containing 10 [Source:HGNC Symbol;Acc:HGNC:20264]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0030016//myofibril;GO:0030017//sarcomere	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051393//alpha-actinin binding	GO:0055013//cardiac muscle cell development	--
ENSG00000198814	3.058	2.148	1.975	2.345	2.434	2.496	159	140.98	88	113	154	122	GK	glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00561//Glycerolipid metabolism	K00864;K00864;K00864	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	"GO:0000166//nucleotide binding;GO:0004370//glycerol kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0006071//glycerol metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006641//triglyceride metabolic process;GO:0016310//phosphorylation;GO:0019432//triglyceride biosynthetic process;GO:0019563//glycerol catabolic process;GO:0046167//glycerol-3-phosphate biosynthetic process	--
ENSG00000198815	13.473	11.461	11.337	11.482	11.44	12.716	1334	1169	901	823	935	905	FOXJ3	forkhead box J3 [Source:HGNC Symbol;Acc:HGNC:29178]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051321//meiotic cell cycle"	Fork_head
ENSG00000198816	49.768	40.471	49.242	62.791	55.292	66.407	1441	1435	1126	1425	1442	1469	ZNF358	zinc finger protein 358 [Source:HGNC Symbol;Acc:HGNC:16838]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0019827//stem cell population maintenance;GO:0021915//neural tube development;GO:0035115//embryonic forelimb morphogenesis	zf-C2H2
ENSG00000198818	24.269	23.402	27.046	29.298	22.76	32.585	520	504	428	465	412	508	SFT2D1	SFT2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21102]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000198821	0	0	0	0	0	0	0	0	0	0	0	0	CD247	CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677]	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview	ko05169//Epstein-Barr virus infection;ko05170//Human immunodeficiency virus 1 infection;ko04650//Natural killer cell mediated cytotoxicity;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06453;K06453;K06453;K06453;K06453;K06453;K06453;K06453	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033001//Fc-gamma receptor III complex;GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex;GO:0042106//gamma-delta T cell receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:1990782//protein tyrosine kinase binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0038094//Fc-gamma receptor signaling pathway;GO:0046629//gamma-delta T cell activation;GO:0046631//alpha-beta T cell activation;GO:0050852//T cell receptor signaling pathway;GO:0065003//protein-containing complex assembly;GO:2000010//positive regulation of protein localization to cell surface	--
ENSG00000198822	0.023	0	0	0	0	0	2	0	0	0	0	0	GRM3	glutamate metabotropic receptor 3 [Source:HGNC Symbol;Acc:HGNC:4595]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signaling molecules and interaction;Signal transduction;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04072//Phospholipase D signaling pathway;ko04724//Glutamatergic synapse;ko05030//Cocaine addiction	K04606;K04606;K04606;K04606	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0097449//astrocyte projection;GO:0098978//glutamatergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane	GO:0001640//adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0001641//group II metabotropic glutamate receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005246//calcium channel regulator activity;GO:0008066//glutamate receptor activity;GO:0097110//scaffold protein binding	"GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007196//adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway;GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0010467//gene expression;GO:0023052//signaling;GO:0051966//regulation of synaptic transmission, glutamatergic"	--
ENSG00000198824	8.191	8.205	7.675	8.33	7.562	7.876	603	575	414	399	498	390	CHAMP1	chromosome alignment maintaining phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:20311]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0090543//Flemming body"	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0031134//sister chromatid biorientation;GO:0034501//protein localization to kinetochore;GO:0035372//protein localization to microtubule;GO:0051315//attachment of mitotic spindle microtubules to kinetochore	--
ENSG00000198825	3.738	3.416	3.127	3.435	3.292	2.901	367	310	234	223	234	215	INPP5F	inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K21798;K21798;K21798	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005905//clathrin-coated pit;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0045334//clathrin-coated endocytic vesicle;GO:0055037//recycling endosome	GO:0005515//protein binding;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0042803//protein homodimerization activity;GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0052834//inositol monophosphate phosphatase activity	GO:0001921//positive regulation of receptor recycling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0008344//adult locomotory behavior;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0016311//dephosphorylation;GO:0031161//phosphatidylinositol catabolic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048681//negative regulation of axon regeneration;GO:0051896//regulation of protein kinase B signaling;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0072583//clathrin-dependent endocytosis;GO:2000145//regulation of cell motility;GO:2001135//regulation of endocytic recycling	--
ENSG00000198826	4.789	3.589	3.1	1.412	1.931	1.82	420.06	308.65	195.7	105.55	152.14	90.6	ARHGAP11A	Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000198829	0	0.011	0	0	0	0	0	1	0	0	0	0	SUCNR1	succinate receptor 1 [Source:HGNC Symbol;Acc:HGNC:4542]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K10042	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0002001//renin secretion into blood stream;GO:0002281//macrophage activation involved in immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0050729//positive regulation of inflammatory response;GO:0050921//positive regulation of chemotaxis;GO:0051592//response to calcium ion;GO:0060177//regulation of angiotensin metabolic process	--
ENSG00000198830	65.676	77.875	68.996	77.121	71.683	55.436	2031	2395	1557	1824	1874	1308	HMGN2	high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986]	-	-	-	-	GO:0000785//chromatin;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding	GO:0006325//chromatin organization;GO:0031640//killing of cells of other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000198832	78.43	88.643	83.054	66.631	64.054	55.868	1129	1283	883	713	779	586	-	-	-	-	-	-	-	-	-	-
ENSG00000198833	21.987	20.239	24.393	20.054	20.488	27.609	1899	1757	1556	1283	1495	1735	UBE2J1	ubiquitin conjugating enzyme E2 J1 [Source:HGNC Symbol;Acc:HGNC:17598]	Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis	K10578;K10578;K10578;K10578	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	"GO:0000209//protein polyubiquitination;GO:0007286//spermatid development;GO:0016567//protein ubiquitination;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032680//regulation of tumor necrosis factor production;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol"	--
ENSG00000198835	0.468	0.399	0.332	0.451	0.264	0.551	21	18	11	15	10	18	GJC2	gap junction protein gamma 2 [Source:HGNC Symbol;Acc:HGNC:17494]	-	-	-	-	GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0033270//paranode region of axon;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043209//myelin sheath;GO:1990769//proximal neuron projection	GO:0005243//gap junction channel activity;GO:1903763//gap junction channel activity involved in cell communication by electrical coupling	GO:0001932//regulation of protein phosphorylation;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007420//brain development;GO:0009636//response to toxic substance;GO:0010628//positive regulation of gene expression;GO:0010644//cell communication by electrical coupling;GO:0055085//transmembrane transport;GO:0070447//positive regulation of oligodendrocyte progenitor proliferation;GO:1904427//positive regulation of calcium ion transmembrane transport;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle	--
ENSG00000198836	12.056	8.934	9.99	7.85	6.914	8.118	1314	1001	677	590	711	590	OPA1	OPA1 mitochondrial dynamin like GTPase [Source:HGNC Symbol;Acc:HGNC:8140]	Human Diseases	Neurodegenerative disease	ko05017//Spinocerebellar ataxia	K17079	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0005874//microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030061//mitochondrial crista;GO:0030425//dendrite;GO:0031966//mitochondrial membrane;GO:1904115//axon cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0008289//lipid binding;GO:0016787//hydrolase activity;GO:0070300//phosphatidic acid binding;GO:1901612//cardiolipin binding	GO:0000002//mitochondrial genome maintenance;GO:0000266//mitochondrial fission;GO:0001843//neural tube closure;GO:0006915//apoptotic process;GO:0007005//mitochondrion organization;GO:0007007//inner mitochondrial membrane organization;GO:0007601//visual perception;GO:0008053//mitochondrial fusion;GO:0019896//axonal transport of mitochondrion;GO:0043066//negative regulation of apoptotic process;GO:0046039//GTP metabolic process;GO:0050896//response to stimulus;GO:0051259//protein complex oligomerization;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0090398//cellular senescence;GO:0097749//membrane tubulation;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000198837	4.566	4.873	4.974	4.602	5.577	6.728	533	558	409	405	554	572	DENND4B	DENN domain containing 4B [Source:HGNC Symbol;Acc:HGNC:29044]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0032483//regulation of Rab protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000198838	0.115	0.034	0.058	0.105	0.025	0.062	9	10	2	5	1	3	RYR3	ryanodine receptor 3 [Source:HGNC Symbol;Acc:HGNC:10485]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Signal transduction;Environmental adaptation;Digestive system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04921//Oxytocin signaling pathway;ko04371//Apelin signaling pathway;ko04713//Circadian entrainment;ko04970//Salivary secretion	K04963;K04963;K04963;K04963;K04963;K04963;K04963;K04963;K04963	GO:0005783//endoplasmic reticulum;GO:0005790//smooth endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0030018//Z disc;GO:0030659//cytoplasmic vesicle membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0043231//intracellular membrane-bounded organelle	GO:0005216//ion channel activity;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015085//calcium ion transmembrane transporter activity;GO:0015278//calcium-release channel activity;GO:0048763//calcium-induced calcium release activity	GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0032879//regulation of localization;GO:0034220//ion transmembrane transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0051289//protein homotetramerization;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0071286//cellular response to magnesium ion;GO:0071313//cellular response to caffeine;GO:0071318//cellular response to ATP;GO:1903779//regulation of cardiac conduction	--
ENSG00000198839	9.311	8.855	7.302	8.772	7.608	8.042	372	345	227	233	246	259	ZNF277	zinc finger protein 277 [Source:HGNC Symbol;Acc:HGNC:13070]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0070301//cellular response to hydrogen peroxide;GO:2000772//regulation of cellular senescence	zf-C2H2
ENSG00000198840	1423.768	1421.893	1624.195	2271.056	1551.469	1815.27	10218	10257	8609	12073	9407	9479	MT-ND3	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 [Source:HGNC Symbol;Acc:HGNC:7458]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03880;K03880;K03880;K03880;K03880;K03880;K03880;K03880;K03880;K03880;K03880;K03880	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006979//response to oxidative stress;GO:0009060//aerobic respiration;GO:0009642//response to light intensity;GO:0009725//response to hormone;GO:0022900//electron transport chain;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0071385//cellular response to glucocorticoid stimulus"	--
ENSG00000198841	5.099	4.955	4.042	4.954	5.026	4.885	180.64	176.44	105.77	130	150.43	125.91	KTI12	KTI12 chromatin associated homolog [Source:HGNC Symbol;Acc:HGNC:25160]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0002098//tRNA wobble uridine modification;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000198842	0.036	0.027	0	0.016	0.016	0.055	3	2	0	1	1	3	STYXL2	serine/threonine/tyrosine interacting like 2 [Source:HGNC Symbol;Acc:HGNC:25034]	-	-	-	-	GO:0005737//cytoplasm;GO:0030017//sarcomere	GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:0033549//MAP kinase phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0043409//negative regulation of MAPK cascade	--
ENSG00000198843	41.24	42.849	42.287	38.462	36.259	44.036	1632	1608	1188	1097	1193	1181	SELENOT	selenoprotein T [Source:HGNC Symbol;Acc:HGNC:18136]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004791//thioredoxin-disulfide reductase activity;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity	GO:0001514//selenocysteine incorporation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0009749//response to glucose;GO:0031016//pancreas development;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0042593//glucose homeostasis;GO:0045454//cell redox homeostasis;GO:0060124//positive regulation of growth hormone secretion;GO:0098869//cellular oxidant detoxification	--
ENSG00000198844	0	0	0	0.019	0	0	0	0	0	1	0	0	ARHGEF15	Rho guanine nucleotide exchange factor 15 [Source:HGNC Symbol;Acc:HGNC:15590]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030425//dendrite;GO:0042995//cell projection	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051496//positive regulation of stress fiber assembly;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0090630//activation of GTPase activity;GO:2000297//negative regulation of synapse maturation	--
ENSG00000198846	4.696	3.836	4.228	5.461	5.922	5.852	397	326	264	342	423	360	TOX	thymocyte selection associated high mobility group box [Source:HGNC Symbol;Acc:HGNC:18988]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding	"GO:0001779//natural killer cell differentiation;GO:0002362//CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment;GO:0002364//NK T cell lineage commitment;GO:0002521//leukocyte differentiation;GO:0006325//chromatin organization;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development;GO:0021895//cerebral cortex neuron differentiation;GO:0030098//lymphocyte differentiation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0043373//CD4-positive, alpha-beta T cell lineage commitment;GO:0043375//CD8-positive, alpha-beta T cell lineage commitment;GO:0048535//lymph node development;GO:0048541//Peyer's patch development;GO:1901537//positive regulation of DNA demethylation;GO:1902232//regulation of positive thymic T cell selection;GO:2000179//positive regulation of neural precursor cell proliferation"	HMG
ENSG00000198848	0	0.183	0.099	0.071	0.113	0	0	7	1	2	2	0	CES1	carboxylesterase 1 [Source:HGNC Symbol;Acc:HGNC:1863]	Metabolism	Xenobiotics biodegradation and metabolism	ko00983//Drug metabolism - other enzymes	K01044	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005811//lipid droplet;GO:0005829//cytosol	GO:0004771//sterol esterase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0080030//methyl indole-3-acetate esterase activity	GO:0006629//lipid metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0009636//response to toxic substance;GO:0010875//positive regulation of cholesterol efflux;GO:0010887//negative regulation of cholesterol storage;GO:0016042//lipid catabolic process;GO:0030855//epithelial cell differentiation;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0051791//medium-chain fatty acid metabolic process;GO:0070857//regulation of bile acid biosynthetic process;GO:0071397//cellular response to cholesterol;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0090122//cholesterol ester hydrolysis involved in cholesterol transport;GO:0090205//positive regulation of cholesterol metabolic process;GO:0120188//regulation of bile acid secretion	--
ENSG00000198851	0	0	0	0	0.177	0	0	0	0	0	4	0	CD3E	CD3e molecule [Source:HGNC Symbol;Acc:HGNC:1674]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune system;Cancer: overview	ko05169//Epstein-Barr virus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko04640//Hematopoietic cell lineage;ko05162//Measles;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K06451;K06451;K06451;K06451;K06451;K06451;K06451;K06451;K06451;K06451;K06451	GO:0001772//immunological synapse;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex;GO:0042106//gamma-delta T cell receptor complex;GO:0043197//dendritic spine;GO:0044297//cell body	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0030159//signaling receptor complex adaptor activity;GO:0042608//T cell receptor binding;GO:0042802//identical protein binding	GO:0001954//positive regulation of cell-matrix adhesion;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002669//positive regulation of T cell anergy;GO:0007166//cell surface receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007172//signal complex assembly;GO:0007186//G protein-coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0016358//dendrite development;GO:0021549//cerebellum development;GO:0031295//T cell costimulation;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:0032753//positive regulation of interleukin-4 production;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0042102//positive regulation of T cell proliferation;GO:0042110//T cell activation;GO:0042981//regulation of apoptotic process;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0045879//negative regulation of smoothened signaling pathway;GO:0046629//gamma-delta T cell activation;GO:0046631//alpha-beta T cell activation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0046649//lymphocyte activation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050852//T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0065003//protein-containing complex assembly;GO:0097190//apoptotic signaling pathway	--
ENSG00000198853	9.534	9.906	10.169	9.617	9.503	10.288	1043	1099	823	777	879	833	RUSC2	RUN and SH3 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23625]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0008150//biological_process	--
ENSG00000198854	0	0	0	0	0	0	0	0	0	0	0	0	C1orf68	chromosome 1 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:29468]	-	-	-	-	-	GO:0003674//molecular_function	GO:0008544//epidermis development	--
ENSG00000198855	5.5	5.482	6.056	4.519	4.962	4.071	368	372	302	226	275	200	FICD	FIC domain protein adenylyltransferase [Source:HGNC Symbol;Acc:HGNC:18416]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0030544//Hsp70 protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0044603//protein adenylylhydrolase activity;GO:0051087//chaperone binding;GO:0070733//protein adenylyltransferase activity	GO:0006986//response to unfolded protein;GO:0018117//protein adenylylation;GO:0034260//negative regulation of GTPase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0044602//protein deadenylylation;GO:1903894//regulation of IRE1-mediated unfolded protein response	--
ENSG00000198856	65.161	66.103	62.529	71.269	58.367	61.128	1431	1456	1014	1158	1081	978	OSTC	oligosaccharyltransferase complex non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:24448]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine	--
ENSG00000198858	19.137	17.905	18.069	21.653	20.928	20.238	711	665	495	593	655	539	R3HDM4	R3H domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28270]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding	-	--
ENSG00000198860	14.873	13.583	14.924	12.845	13.116	18.011	577	530	436	375	422	483	TSEN15	tRNA splicing endonuclease subunit 15 [Source:HGNC Symbol;Acc:HGNC:16791]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0005515//protein binding	"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0008033//tRNA processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis"	--
ENSG00000198862	5.586	3.699	3.801	3.273	3.538	3.444	878	587	447	386	476	399	LTN1	listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1990112//RQC complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0043023//ribosomal large subunit binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0072344//rescue of stalled ribosome;GO:1990116//ribosome-associated ubiquitin-dependent protein catabolic process	--
ENSG00000198863	5.396	5.087	6.059	5.755	5.427	5.876	537	560	461	408	464	420	RUNDC1	RUN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25418]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0001701//in utero embryonic development;GO:0090630//activation of GTPase activity	--
ENSG00000198865	0.37	0.194	0.247	0.131	0.159	0.407	26.78	14.11	13.2	7.04	9.76	19.76	CCDC152	coiled-coil domain containing 152 [Source:HGNC Symbol;Acc:HGNC:34438]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000198870	0.136	0.068	0.092	0.023	0.02	0	8	4	4	1	1	0	STKLD1	serine/threonine kinase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28669]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation	--
ENSG00000198873	0.305	0.282	0.394	0.393	0.243	0.341	43	40	41	41	29	35	GRK5	G protein-coupled receptor kinase 5 [Source:HGNC Symbol;Acc:HGNC:4544]	Cellular Processes;Organismal Systems;Human Diseases	Transport and catabolism;Immune system;Substance dependence	ko04144//Endocytosis;ko04062//Chemokine signaling pathway;ko05032//Morphine addiction	K08291;K08291;K08291	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0031965//nuclear membrane	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004703//G protein-coupled receptor kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0047696//beta-adrenergic receptor kinase activity	GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007217//tachykinin receptor signaling pathway;GO:0008277//regulation of G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009966//regulation of signal transduction;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0045444//fat cell differentiation;GO:0046777//protein autophosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000198874	8.544	7.263	8.05	8.626	7.109	7.465	555.65	487.75	410.38	441.35	414.87	345	TYW1	tRNA-yW synthesizing protein 1 homolog [Source:HGNC Symbol;Acc:HGNC:25598]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0010181//FMN binding;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0102521//tRNA-4-demethylwyosine synthase activity"	GO:0008033//tRNA processing;GO:0031591//wybutosine biosynthetic process	--
ENSG00000198876	23.327	22.874	22.989	20.638	20.43	23.243	1738	1713	1265	1139	1286	1260	DCAF12	DDB1 and CUL4 associated factor 12 [Source:HGNC Symbol;Acc:HGNC:19911]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0010506//regulation of autophagy;GO:0016567//protein ubiquitination;GO:0140627//ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	--
ENSG00000198879	0.253	0.788	0.239	0.301	0.42	0.276	39	42	29	29	46	33	SFMBT2	Scm like with four mbt domains 2 [Source:HGNC Symbol;Acc:HGNC:20256]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000198881	0.723	0.568	0.412	0.719	0.495	0.628	19	15	8	14	11	12	ASB12	ankyrin repeat and SOCS box containing 12 [Source:HGNC Symbol;Acc:HGNC:19763]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000198883	0	0	0	0	0	0.021	0	0	0	0	0	1	PNMA5	PNMA family member 5 [Source:HGNC Symbol;Acc:HGNC:18743]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0043065//positive regulation of apoptotic process	--
ENSG00000198885	0.468	0.709	0.705	0.71	0.491	0.48	27	44	24	22	22	21	ITPRIPL1	ITPRIP like 1 [Source:HGNC Symbol;Acc:HGNC:29371]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000198886	8457.247	9530.862	9342.077	11738.231	11459.626	9394.953	241729	273816	197211	248521	276727	195384	MT-ND4	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 [Source:HGNC Symbol;Acc:HGNC:7459]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03881;K03881;K03881;K03881;K03881;K03881;K03881;K03881;K03881;K03881;K03881;K03881	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0003954//NADH dehydrogenase activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0048039//ubiquinone binding	"GO:0001666//response to hypoxia;GO:0001701//in utero embryonic development;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007568//aging;GO:0009060//aerobic respiration;GO:0015990//electron transport coupled proton transport;GO:0021549//cerebellum development;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0035094//response to nicotine;GO:0042773//ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0045471//response to ethanol"	--
ENSG00000198887	5.122	3.144	2.985	2.363	3.261	3.442	632	390	272	216	340	309	SMC5	structural maintenance of chromosomes 5 [Source:HGNC Symbol;Acc:HGNC:20465]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000781//chromosome, telomeric region;GO:0000803//sex chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0030054//cell junction;GO:0030915//Smc5-Smc6 complex;GO:0035061//interchromatin granule;GO:0035861//site of double-strand break"	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	"GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0016925//protein sumoylation;GO:0018393//internal peptidyl-lysine acetylation;GO:0019827//stem cell population maintenance;GO:0030261//chromosome condensation;GO:0032204//regulation of telomere maintenance;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:0044772//mitotic cell cycle phase transition;GO:0051301//cell division;GO:0051984//positive regulation of chromosome segregation;GO:0071459//protein localization to chromosome, centromeric region;GO:0090398//cellular senescence"	--
ENSG00000198888	1982.97	2203.42	2376.677	2962.715	2639.306	2419.964	39321	43917	34807	43517	44216	34915	MT-ND1	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 [Source:HGNC Symbol;Acc:HGNC:7455]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03878;K03878;K03878;K03878;K03878;K03878;K03878;K03878;K03878;K03878;K03878;K03878	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0022900//electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000198889	0.115	0.172	0.059	0.019	0.102	0.178	8	12	3	1	6	9	DCAF12L1	DDB1 and CUL4 associated factor 12 like 1 [Source:HGNC Symbol;Acc:HGNC:29395]	-	-	-	-	GO:0005575//cellular_component;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000198890	25.678	24.428	24.605	28.806	26.323	27.478	1396	1335	988	1160	1209	1087	PRMT6	protein arginine methyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18241]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0016740//transferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042393//histone binding;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0070611//histone methyltransferase activity (H3-R2 specific);GO:0070612//histone methyltransferase activity (H2A-R3 specific)	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006325//chromatin organization;GO:0006974//cellular response to DNA damage stimulus;GO:0010821//regulation of mitochondrion organization;GO:0016571//histone methylation;GO:0018216//peptidyl-arginine methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0031064//negative regulation of histone deacetylation;GO:0032259//methylation;GO:0034970//histone H3-R2 methylation;GO:0035246//peptidyl-arginine N-methylation;GO:0043985//histone H4-R3 methylation;GO:0045652//regulation of megakaryocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0090398//cellular senescence;GO:1901796//regulation of signal transduction by p53 class mediator"	--
ENSG00000198892	17.44	18.891	19.419	20.635	19.765	18.231	518	564	426	454	496	394	SHISA4	shisa family member 4 [Source:HGNC Symbol;Acc:HGNC:27139]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000198894	11.88	10.087	10.067	8.539	9.238	10.373	973	854	667	545	676	637	CIPC	CLOCK interacting pacemaker [Source:HGNC Symbol;Acc:HGNC:20365]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	"GO:0042754//negative regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process"	--
ENSG00000198898	52.615	44.23	51.702	45.836	39.567	52.343	2159	1989	1508.66	1353	1319	1525	CAPZA2	capping actin protein of muscle Z-line subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:1490]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K10364	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005903//brush border;GO:0008290//F-actin capping protein complex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030863//cortical cytoskeleton;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0051016//barbed-end actin filament capping;GO:0051693//actin filament capping;GO:0065003//protein-containing complex assembly	--
ENSG00000198899	8224.676	8864.26	8976.142	11056.718	10151.916	9415.123	116176	125854	93643	115687	121151	96765	MT-ATP6	mitochondrially encoded ATP synthase membrane subunit 6 [Source:HGNC Symbol;Acc:HGNC:7414]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02126;K02126;K02126;K02126;K02126;K02126;K02126;K02126;K02126;K02126;K02126	"GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0007568//aging;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0055093//response to hyperoxia	--
ENSG00000198900	26.44	24.766	23.163	14.921	18.079	20.812	2048	1928	1325	856	1183	1173	TOP1	DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986]	-	-	-	-	GO:0000228//nuclear chromosome;GO:0000932//P-body;GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0032993//protein-DNA complex;GO:0043204//perikaryon	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003916//DNA topoisomerase activity;GO:0003917//DNA topoisomerase type I (single strand cut, ATP-independent) activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016853//isomerase activity;GO:0019904//protein domain specific binding;GO:0097100//supercoiled DNA binding"	GO:0006260//DNA replication;GO:0006265//DNA topological change;GO:0006338//chromatin remodeling;GO:0007059//chromosome segregation;GO:0007623//circadian rhythm;GO:0009410//response to xenobiotic stimulus;GO:0012501//programmed cell death;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032922//circadian regulation of gene expression;GO:0040016//embryonic cleavage;GO:0048511//rhythmic process	--
ENSG00000198901	4.296	6.45	5.503	3.368	4.1	3.54	205.07	305.69	215.61	138.19	190.97	146.02	PRC1	protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341]	-	-	-	-	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0045171//intercellular bridge;GO:0070938//contractile ring;GO:1990023//mitotic spindle midzone	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding	GO:0000022//mitotic spindle elongation;GO:0000226//microtubule cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0032465//regulation of cytokinesis;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division	--
ENSG00000198908	4.012	3.354	3.407	2.722	3.822	4.247	331.53	281.34	212.83	169.91	270.9	259.71	BHLHB9	basic helix-loop-helix family member b9 [Source:HGNC Symbol;Acc:HGNC:29353]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0007611//learning or memory;GO:0043524//negative regulation of neuron apoptotic process;GO:0050769//positive regulation of neurogenesis;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis	--
ENSG00000198909	4.9	4.668	6.498	5.511	5.053	4.597	432.51	404.8	387.09	329.07	368.68	288	MAP3K3	mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Signal transduction;Infectious disease: viral;Nervous system;Cancer: overview;Endocrine system	ko04010//MAPK signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04722//Neurotrophin signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway	K04421;K04421;K04421;K04421;K04421	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0000165//MAPK cascade;GO:0001568//blood vessel development;GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046777//protein autophosphorylation;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:1900745//positive regulation of p38MAPK cascade;GO:2000773//negative regulation of cellular senescence	--
ENSG00000198910	0.301	0.336	0.372	0.474	0.355	0.324	28	26	24	32	27	23	L1CAM	L1 cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:6470]	Organismal Systems;Environmental Information Processing	Development and regeneration;Signaling molecules and interaction	ko04360//Axon guidance;ko04514//Cell adhesion molecules	K06550;K06550	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044295//axonal growth cone;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0019904//protein domain specific binding	GO:0006935//chemotaxis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007160//cell-matrix adhesion;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0031175//neuron projection development;GO:0045773//positive regulation of axon extension;GO:0050808//synapse organization;GO:0061564//axon development	--
ENSG00000198911	89.317	88.411	99.832	109.879	109.823	118.029	9705	9642	8010	8842	10081	9331	SREBF2	sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290]	-	-	-	-	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032937//SREBP-SCAP-Insig complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0008593//regulation of Notch signaling pathway;GO:0009267//cellular response to starvation;GO:0010886//positive regulation of cholesterol storage;GO:0032933//SREBP signaling pathway;GO:0042632//cholesterol homeostasis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0071499//cellular response to laminar fluid shear stress;GO:0090370//negative regulation of cholesterol efflux;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903146//regulation of autophagy of mitochondrion;GO:1903955//positive regulation of protein targeting to mitochondrion"	bHLH
ENSG00000198912	9.555	8.7	9.71	7.147	7.799	7.551	331	302	247	184	228	191	C1orf174	chromosome 1 open reading frame 174 [Source:HGNC Symbol;Acc:HGNC:27915]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000198914	0	0	0	0	0	0.015	0	0	0	0	0	1	POU3F3	POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9216]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0071837//HMG box domain binding"	"GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0007420//brain development;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048878//chemical homeostasis;GO:0071918//urea transmembrane transport;GO:0072218//metanephric ascending thin limb development;GO:0072227//metanephric macula densa development;GO:0072233//metanephric thick ascending limb development;GO:0072236//metanephric loop of Henle development;GO:0072240//metanephric DCT cell differentiation"	Pou
ENSG00000198915	8.163	7.899	7.704	3.522	5.793	3.56	377	399	257	177	197	169	RASGEF1A	RasGEF domain family member 1A [Source:HGNC Symbol;Acc:HGNC:24246]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0016477//cell migration;GO:0043547//positive regulation of GTPase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000198917	7.774	7.653	6.87	8.975	9.424	6.503	390	411.99	339.38	336.73	389.65	287.29	SPOUT1	SPOUT domain containing methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26933]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0031616//spindle pole centrosome;GO:0072686//mitotic spindle"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0035198//miRNA binding	GO:0007049//cell cycle;GO:0010608//posttranscriptional regulation of gene expression;GO:0032259//methylation;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0051301//cell division;GO:0051661//maintenance of centrosome location	--
ENSG00000198918	281.48	265.036	276.675	340.117	234.258	276.255	2277	2155	1653	2038	1601	1626	RPL39	ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:10350]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02924;K02924	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0002181//cytoplasmic translation;GO:0002227//innate immune response in mucosa;GO:0006412//translation;GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000198919	4.743	4.022	3.397	2.68	2.652	3.178	422	371	232	173	228	223	DZIP3	DAZ interacting zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:30938]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019902//phosphatase binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination	--
ENSG00000198920	4.3	3.809	3.387	3.205	3.649	3.376	369.97	337.98	228	190.87	283.9	222.8	KIAA0753	KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite	GO:0005515//protein binding	GO:0007099//centriole replication;GO:0071539//protein localization to centrosome	--
ENSG00000198924	3.561	3.543	3.804	2.832	2.667	2.948	322	317	254	192	199	198	DCLRE1A	DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0003677//DNA binding;GO:0003684//damaged DNA binding;GO:0008800//beta-lactamase activity;GO:0016787//hydrolase activity;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0031848//protection from non-homologous end joining at telomere;GO:0036297//interstrand cross-link repair;GO:0051301//cell division;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000198925	18.386	24.238	21.717	25.59	25.083	27.309	1313.24	1379.8	994.95	1092.12	1324.37	1030.4	ATG9A	autophagy related 9A [Source:HGNC Symbol;Acc:HGNC:22408]	Cellular Processes;Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K17907;K17907;K17907	GO:0000139//Golgi membrane;GO:0000407//phagophore assembly site;GO:0000421//autophagosome membrane;GO:0005739//mitochondrion;GO:0005768//endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0034045//phagophore assembly site membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane	GO:0005515//protein binding;GO:0017128//phospholipid scramblase activity	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006869//lipid transport;GO:0006914//autophagy;GO:0010940//positive regulation of necrotic cell death;GO:0015031//protein transport;GO:0017121//plasma membrane phospholipid scrambling;GO:0034497//protein localization to phagophore assembly site;GO:0044805//late nucleophagy;GO:0060349//bone morphogenesis	--
ENSG00000198929	2.955	3.363	3.283	3.935	3.516	4.353	201.78	224.46	169	195.99	210	222.46	NOS1AP	nitric oxide synthase 1 adaptor protein [Source:HGNC Symbol;Acc:HGNC:16859]	Organismal Systems	Environmental adaptation	ko04713//Circadian entrainment	K16513	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005901//caveola;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0042383//sarcolemma;GO:0048471//perinuclear region of cytoplasm;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0050998//nitric-oxide synthase binding	GO:0003062//regulation of heart rate by chemical signal;GO:0010628//positive regulation of gene expression;GO:0010750//positive regulation of nitric oxide mediated signal transduction;GO:0045428//regulation of nitric oxide biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0098901//regulation of cardiac muscle cell action potential;GO:0098974//postsynaptic actin cytoskeleton organization;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:1902261//positive regulation of delayed rectifier potassium channel activity;GO:1902514//regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;GO:1903762//positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:2000170//positive regulation of peptidyl-cysteine S-nitrosylation	--
ENSG00000198930	0	0	0	0	0	0	0	0	0	0	0	0	CSAG1	chondrosarcoma associated gene 1 [Source:HGNC Symbol;Acc:HGNC:24294]	-	-	-	-	-	-	-	--
ENSG00000198931	25.748	30.918	28.771	33.656	28.922	27.37	442	538	355	429	426	339	APRT	adenine phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:626]	Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism	K00759;K00759	GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome	GO:0002055//adenine binding;GO:0003999//adenine phosphoribosyltransferase activity;GO:0005515//protein binding;GO:0016208//AMP binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006166//purine ribonucleoside salvage;GO:0006168//adenine salvage;GO:0007595//lactation;GO:0007625//grooming behavior;GO:0032263//GMP salvage;GO:0032264//IMP salvage;GO:0032869//cellular response to insulin stimulus;GO:0044209//AMP salvage;GO:0046083//adenine metabolic process	--
ENSG00000198932	2.909	2.923	2.807	2.062	2.377	2.156	358	364	256	186	248	191	GPRASP1	G protein-coupled receptor associated sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:24834]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0008333//endosome to lysosome transport;GO:1990172//G protein-coupled receptor catabolic process	--
ENSG00000198933	10.701	8.96	13.887	13.889	11.274	14.451	658	562	515	613	609	573	TBKBP1	TBK1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:30140]	Organismal Systems	Immune system	ko04622//RIG-I-like receptor signaling pathway	K12652	GO:0005737//cytoplasm;GO:1902554//serine/threonine protein kinase complex	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway	--
ENSG00000198934	3.238	3.353	4.061	2.651	3.785	3.356	244	254	226	148	241	184	MAGEE1	MAGE family member E1 [Source:HGNC Symbol;Acc:HGNC:24934]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000198937	13.149	16.603	16.319	21.62	12.57	16.102	156	198	143	190	126	139	CCDC167	coiled-coil domain containing 167 [Source:HGNC Symbol;Acc:HGNC:21239]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000198938	11541.888	12458.365	13157.602	17122.231	15639.097	14349.036	187691	203636	158027	206247	214862	169779	MT-CO3	mitochondrially encoded cytochrome c oxidase III [Source:HGNC Symbol;Acc:HGNC:7422]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262;K02262	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045277//respiratory chain complex IV	GO:0004129//cytochrome-c oxidase activity;GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0015453//oxidoreduction-driven active transmembrane transporter activity	"GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0008535//respiratory chain complex IV assembly;GO:0009060//aerobic respiration;GO:0019646//aerobic electron transport chain;GO:0022904//respiratory electron transport chain;GO:0045333//cellular respiration;GO:0055085//transmembrane transport;GO:1902600//proton transmembrane transport"	--
ENSG00000198939	1.18	0.738	0.883	0.697	0.687	1.108	59	34	30	17	29	35	ZFP2	ZFP2 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:26138]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000198944	0.36	0.454	0.244	0.598	0.426	0.532	26	33	13	32	26	28	SOWAHA	sosondowah ankyrin repeat domain family member A [Source:HGNC Symbol;Acc:HGNC:27033]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000198945	10.14	7.122	9.235	7.766	8.284	10.813	625	474	382	379	464	447	L3MBTL3	L3MBTL histone methyl-lysine binding protein 3 [Source:HGNC Symbol;Acc:HGNC:23035]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0030225//macrophage differentiation;GO:0030851//granulocyte differentiation;GO:0043249//erythrocyte maturation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090308//regulation of DNA methylation-dependent heterochromatin assembly"	Others
ENSG00000198947	9.548	6.894	7.758	6.114	5.448	6.134	783	600	449	341	427	405	DMD	dystrophin [Source:HGNC Symbol;Acc:HGNC:2928]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cardiovascular disease;Cardiovascular disease;Cardiovascular disease;Cardiovascular disease	ko05414//Dilated cardiomyopathy;ko05416//Viral myocarditis;ko05410//Hypertrophic cardiomyopathy;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K10366;K10366;K10366;K10366	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005856//cytoskeleton;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016013//syntrophin complex;GO:0016020//membrane;GO:0016328//lateral plasma membrane;GO:0030016//myofibril;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030055//cell-substrate junction;GO:0030141//secretory granule;GO:0030175//filopodium;GO:0030424//axon;GO:0030672//synaptic vesicle membrane;GO:0030864//cortical actin cytoskeleton;GO:0031527//filopodium membrane;GO:0032991//protein-containing complex;GO:0042383//sarcolemma;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043034//costamere;GO:0044306//neuron projection terminus;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0097449//astrocyte projection;GO:0099617//matrix side of mitochondrial inner membrane;GO:0110165//cellular anatomical entity;GO:0120025//plasma membrane bounded cell projection	"GO:0002162//dystroglycan binding;GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005521//lamin binding;GO:0008270//zinc ion binding;GO:0008307//structural constituent of muscle;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0017022//myosin binding;GO:0017166//vinculin binding;GO:0030165//PDZ domain binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0050998//nitric-oxide synthase binding;GO:0051015//actin filament binding"	"GO:0001954//positive regulation of cell-matrix adhesion;GO:0002027//regulation of heart rate;GO:0005975//carbohydrate metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0007517//muscle organ development;GO:0007519//skeletal muscle tissue development;GO:0007568//aging;GO:0008065//establishment of blood-nerve barrier;GO:0008284//positive regulation of cell population proliferation;GO:0009414//response to water deprivation;GO:0010468//regulation of gene expression;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0010976//positive regulation of neuron projection development;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0014819//regulation of skeletal muscle contraction;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0014904//myotube cell development;GO:0021629//olfactory nerve structural organization;GO:0021987//cerebral cortex development;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034613//cellular protein localization;GO:0034622//cellular protein-containing complex assembly;GO:0035633//maintenance of blood-brain barrier;GO:0035994//response to muscle stretch;GO:0042391//regulation of membrane potential;GO:0042692//muscle cell differentiation;GO:0043043//peptide biosynthetic process;GO:0043403//skeletal muscle tissue regeneration;GO:0044458//motile cilium assembly;GO:0045213//neurotransmitter receptor metabolic process;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0046716//muscle cell cellular homeostasis;GO:0048666//neuron development;GO:0048812//neuron projection morphogenesis;GO:0051017//actin filament bundle assembly;GO:0051647//nucleus localization;GO:0051726//regulation of cell cycle;GO:0055001//muscle cell development;GO:0060048//cardiac muscle contraction;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060857//establishment of glial blood-brain barrier;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0086001//cardiac muscle cell action potential;GO:0090257//regulation of muscle system process;GO:0090287//regulation of cellular response to growth factor stimulus;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:2000651//positive regulation of sodium ion transmembrane transporter activity"	--
ENSG00000198948	97.702	89.438	87.981	64.894	75.959	87.034	9180	8520	6519	4887	6392	6050	MFAP3L	microfibril associated protein 3 like [Source:HGNC Symbol;Acc:HGNC:29083]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005515//protein binding	-	--
ENSG00000198951	19.882	21.834	22.572	21.677	21.114	17.833	1144	1273	903	872	1021	720	NAGA	alpha-N-acetylgalactosaminidase [Source:HGNC Symbol;Acc:HGNC:7631]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K01204;K01204;K01204	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004557//alpha-galactosidase activity;GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0042803//protein homodimerization activity"	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016052//carbohydrate catabolic process;GO:0016139//glycoside catabolic process;GO:0019377//glycolipid catabolic process;GO:0046477//glycosylceramide catabolic process	--
ENSG00000198952	31.587	33.057	35.824	34.292	34.159	39.998	2987	3142	2502	2402	2729	2752	SMG5	SMG5 nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:24644]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K11125	GO:0005634//nucleus;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042162//telomeric DNA binding;GO:0042826//histone deacetylase binding;GO:0051721//protein phosphatase 2A binding;GO:0070034//telomerase RNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006406//mRNA export from nucleus;GO:0032204//regulation of telomere maintenance;GO:0032210//regulation of telomere maintenance via telomerase;GO:0035303//regulation of dephosphorylation"	--
ENSG00000198954	15.999	16.325	17.69	13.473	13.637	15.546	817	838	667	510	589	578	KIFBP	kinesin family binding protein [Source:HGNC Symbol;Acc:HGNC:23419]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0019894//kinesin binding	GO:0001701//in utero embryonic development;GO:0006839//mitochondrial transport;GO:0007399//nervous system development;GO:0030154//cell differentiation	--
ENSG00000198959	48.326	56.543	18.267	27.023	33.171	17.334	4796	4913	1269	1820	2889	1218	TGM2	transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778]	Human Diseases	Neurodegenerative disease	ko05016//Huntington disease	K05625	GO:0000785//chromatin;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0031226//intrinsic component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008233//peptidase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050568//protein-glutamine glutaminase activity;GO:0120294//peptide serotonyltransferase activity;GO:0120295//histone serotonyltransferase activity;GO:0120296//peptide dopaminyltransferase activity;GO:0120297//histone dopaminyltransferase activity;GO:0120298//peptide noradrenalinyltransferase activity;GO:0120299//peptide histaminyltransferase activity	GO:0006508//proteolysis;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0018149//peptide cross-linking;GO:0018277//protein deamination;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043277//apoptotic cell clearance;GO:0043547//positive regulation of GTPase activity;GO:0045785//positive regulation of cell adhesion;GO:0050769//positive regulation of neurogenesis;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0060348//bone development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060662//salivary gland cavitation;GO:0071314//cellular response to cocaine;GO:1903351//cellular response to dopamine;GO:1904015//cellular response to serotonin;GO:2000425//regulation of apoptotic cell clearance	--
ENSG00000198960	13.897	15.314	13.933	15.241	14.297	14.42	530	586	392	430	461	399	ARMCX6	armadillo repeat containing X-linked 6 [Source:HGNC Symbol;Acc:HGNC:26094]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000198961	56.438	47.333	48.512	34.771	38.498	42.995	5639	4773	3592	2589	3276	3124	PJA2	praja ring finger ubiquitin ligase 2 [Source:HGNC Symbol;Acc:HGNC:17481]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0045111//intermediate filament cytoskeleton;GO:0045202//synapse	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0046872//metal ion binding	GO:0006954//inflammatory response;GO:0007616//long-term memory;GO:0010738//regulation of protein kinase A signaling;GO:0016567//protein ubiquitination;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0035329//hippo signaling;GO:0043030//regulation of macrophage activation;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:1900745//positive regulation of p38MAPK cascade	--
ENSG00000198963	1.833	1.253	1.289	0.929	0.866	0.546	247	192	108	114	132	73	RORB	RAR related orphan receptor B [Source:HGNC Symbol;Acc:HGNC:10259]	Organismal Systems	Environmental adaptation	ko04710//Circadian rhythm	K08533	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008502//melatonin receptor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0010468//regulation of gene expression;GO:0030522//intracellular receptor signaling pathway;GO:0035881//amacrine cell differentiation;GO:0042462//eye photoreceptor cell development;GO:0042752//regulation of circadian rhythm;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046548//retinal rod cell development;GO:0046549//retinal cone cell development;GO:0048511//rhythmic process;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye;GO:0071300//cellular response to retinoic acid"	THR-like
ENSG00000198964	19.674	16.668	18.515	17.408	17.809	21.448	1291	1121	860	848	1024	968	SGMS1	sphingomyelin synthase 1 [Source:HGNC Symbol;Acc:HGNC:29799]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04714;K04714;K04714	GO:0000138//Golgi trans cisterna;GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	"GO:0002950//ceramide phosphoethanolamine synthase activity;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0033188//sphingomyelin synthase activity;GO:0047493//ceramide cholinephosphotransferase activity"	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0006915//apoptotic process;GO:0016310//phosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:2001242//regulation of intrinsic apoptotic signaling pathway	--
ENSG00000198965	0	0	0	0	0	0	0	0	0	0	0	0	OR10R2	olfactory receptor family 10 subfamily R member 2 [Source:HGNC Symbol;Acc:HGNC:14820]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000198967	0	0	0	0	0	0	0	0	0	0	0	0	OR10Z1	olfactory receptor family 10 subfamily Z member 1 [Source:HGNC Symbol;Acc:HGNC:14996]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000203326	1.328	1.371	0.957	1.786	0.844	0.486	130	76	58	50	57	45	ZNF525	zinc finger protein 525 [Source:HGNC Symbol;Acc:HGNC:29423]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000203485	41.154	38.452	48.366	54.929	59.463	53.485	2797	2698	2451	2760	3248	2474	INF2	inverted formin 2 [Source:HGNC Symbol;Acc:HGNC:23791]	-	-	-	-	GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0016043//cellular component organization;GO:0030036//actin cytoskeleton organization;GO:0090140//regulation of mitochondrial fission	--
ENSG00000203499	1.022	1.297	1.169	1.094	1.084	0.993	58	74	49	46	52	41	IQANK1	IQ motif and ankyrin repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:49576]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:2000812//regulation of barbed-end actin filament capping	--
ENSG00000203546	0.27	0.537	0.193	0.577	0.632	0.98	4.19	16.34	2.22	6.64	8.3	21.97	DTD2	novel protein	-	-	-	-	GO:0005737//cytoplasm	GO:0002161//aminoacyl-tRNA editing activity;GO:0051499//D-aminoacyl-tRNA deacylase activity	GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000203618	1.247	1.337	0.24	1.386	1.053	0.53	24.81	26.73	3.53	20.42	17.69	7.67	GP1BB	glycoprotein Ib platelet subunit beta [Source:HGNC Symbol;Acc:HGNC:4440]	Organismal Systems;Organismal Systems;Environmental Information Processing	Immune system;Immune system;Signaling molecules and interaction	ko04640//Hematopoietic cell lineage;ko04611//Platelet activation;ko04512//ECM-receptor interaction	K06262;K06262;K06262	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990779//glycoprotein Ib-IX-V complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007599//hemostasis;GO:0010572//positive regulation of platelet activation;GO:0030168//platelet activation;GO:0035855//megakaryocyte development;GO:0051209//release of sequestered calcium ion into cytosol"	--
ENSG00000203661	0	0	0	0	0	0	0	0	0	0	0	0	OR2T5	olfactory receptor family 2 subfamily T member 5 [Source:HGNC Symbol;Acc:HGNC:15017]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000203663	0.092	0.011	0.015	0.031	0.027	0	8.09	1	1	2	2.01	0	OR2L2	olfactory receptor family 2 subfamily L member 2 [Source:HGNC Symbol;Acc:HGNC:8266]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000203666	4.469	3.832	3.585	2.618	2.615	3.809	83	80	67	36	51	57	EFCAB2	EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000203667	19.893	22.263	19.498	16.914	16.084	19.364	909.38	1041.55	685.52	596.41	646.84	651.93	COX20	cytochrome c oxidase assembly factor COX20 [Source:HGNC Symbol;Acc:HGNC:26970]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18184	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000203668	1.302	0.911	0.801	0.675	0.917	0.676	208.31	146.5	94.6	80.01	118.1	78.62	CHML	CHM like Rab escort protein [Source:HGNC Symbol;Acc:HGNC:1941]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005968//Rab-protein geranylgeranyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0031267//small GTPase binding	GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0016192//vesicle-mediated transport;GO:0018344//protein geranylgeranylation;GO:0050790//regulation of catalytic activity	--
ENSG00000203685	1.005	0.853	1.319	0.529	0.733	1.234	148	138	134	61	94	135	STUM	"stum, mechanosensory transduction mediator homolog [Source:HGNC Symbol;Acc:HGNC:30491]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000203697	0	0	0	0	0.022	0	0	0	0	0	1	0	CAPN8	calpain 8 [Source:HGNC Symbol;Acc:HGNC:1485]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000203705	5.33	2.88	3.491	2.84	4.029	4.452	179	125	109	92	121	113	TATDN3	TatD DNase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:27010]	-	-	-	-	GO:0005634//nucleus	"GO:0004518//nuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000203710	0	0	0	0	0.015	0	0	0	0	0	1	0	CR1	complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]	Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Immune system;Infectious disease: bacterial;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Infectious disease: parasitic	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04640//Hematopoietic cell lineage;ko05140//Leishmaniasis;ko04610//Complement and coagulation cascades;ko05134//Legionellosis;ko05144//Malaria	K04011;K04011;K04011;K04011;K04011;K04011;K04011	GO:0005615//extracellular space;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0044853//plasma membrane raft;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane	GO:0001618//virus receptor activity;GO:0001851//complement component C3b binding;GO:0001855//complement component C4b binding;GO:0001861//complement component C4b receptor activity;GO:0004877//complement component C3b receptor activity;GO:0005515//protein binding	"GO:0001970//positive regulation of activation of membrane attack complex;GO:0001971//negative regulation of activation of membrane attack complex;GO:0002376//immune system process;GO:0002430//complement receptor mediated signaling pathway;GO:0002435//immune complex clearance by erythrocytes;GO:0002638//negative regulation of immunoglobulin production;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0007009//plasma membrane organization;GO:0008284//positive regulation of cell population proliferation;GO:0032689//negative regulation of interferon-gamma production;GO:0032703//negative regulation of interleukin-2 production;GO:0042130//negative regulation of T cell proliferation;GO:0045087//innate immune response;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045916//negative regulation of complement activation;GO:0045918//negative regulation of cytolysis;GO:0045957//negative regulation of complement activation, alternative pathway;GO:0045959//negative regulation of complement activation, classical pathway;GO:0046718//viral entry into host cell;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:1900005//positive regulation of serine-type endopeptidase activity;GO:1900099//negative regulation of plasma cell differentiation;GO:1904669//ATP export"	--
ENSG00000203722	0.107	0.226	0.072	0.373	0.126	0.115	2	5	1	6	2	2	RAET1G	retinoic acid early transcript 1G [Source:HGNC Symbol;Acc:HGNC:16795]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07987	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0046703//natural killer cell lectin-like receptor binding	GO:0002376//immune system process;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0042267//natural killer cell mediated cytotoxicity	--
ENSG00000203724	1.446	1.439	1.414	1.41	1.997	0.994	18	18	13	13	21	9	C1orf53	chromosome 1 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:30003]	-	-	-	-	-	-	-	--
ENSG00000203727	2.85	2.146	2.673	3.169	2.733	4.497	374	283	259	308	303	359	SAMD5	sterile alpha motif domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21180]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000203730	0	0	0	0	0	0	0	0	0	0	0	0	TEDDM1	transmembrane epididymal protein 1 [Source:HGNC Symbol;Acc:HGNC:30233]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000203733	0	0	0	0	0	0	0	0	0	0	0	0	GJE1	gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251]	-	-	-	-	GO:0005886//plasma membrane;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005243//gap junction channel activity	GO:0000902//cell morphogenesis;GO:0002088//lens development in camera-type eye;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0035265//organ growth;GO:0055085//transmembrane transport	--
ENSG00000203734	0.023	0	0.016	0.015	0	0.031	2.08	0	1.06	1	0	2	ECT2L	epithelial cell transforming 2 like [Source:HGNC Symbol;Acc:HGNC:21118]	-	-	-	-	-	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000203737	0	0	0	0	0	0	0	0	0	0	0	0	GPR52	G protein-coupled receptor 52 [Source:HGNC Symbol;Acc:HGNC:4508]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008020//G protein-coupled photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0007626//locomotory behavior;GO:0009410//response to xenobiotic stimulus;GO:0009584//detection of visible light;GO:0071482//cellular response to light stimulus	--
ENSG00000203740	0.091	0	0	0	0	0	4	0	0	0	0	0	NTMT2	N-terminal Xaa-Pro-Lys N-methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:31932]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0071885//N-terminal protein N-methyltransferase activity	GO:0006480//N-terminal protein amino acid methylation;GO:0032259//methylation	--
ENSG00000203747	0	0	0	0	0.137	0	0	0	0	0	5	0	FCGR3A	Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619]	Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Immune system;Infectious disease: bacterial;Transport and catabolism;Immune disease;Immune system;Immune system;Infectious disease: bacterial;Infectious disease: parasitic;Development and regeneration	ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko04650//Natural killer cell mediated cytotoxicity;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko05140//Leishmaniasis;ko04380//Osteoclast differentiation	K06463;K06463;K06463;K06463;K06463;K06463;K06463;K06463;K06463	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033001//Fc-gamma receptor III complex;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0019772//low-affinity IgG receptor activity;GO:0019864//IgG binding;GO:0140375//immune receptor activity	GO:0001788//antibody-dependent cellular cytotoxicity;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0019722//calcium-mediated signaling;GO:0030101//natural killer cell activation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0038094//Fc-gamma receptor signaling pathway;GO:0042116//macrophage activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0043320//natural killer cell degranulation;GO:0050776//regulation of immune response	--
ENSG00000203756	0	0	0	0	0	0	0	0	0	0	0	0	TMEM244	transmembrane protein 244 [Source:HGNC Symbol;Acc:HGNC:21571]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000203757	0	0	0	0	0	0	0	0	0	0	0	0	OR6K3	olfactory receptor family 6 subfamily K member 3 [Source:HGNC Symbol;Acc:HGNC:15030]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000203760	7.1	8.033	6.213	3.21	2.257	3.845	115	127	75	38	32	46	CENPW	centromere protein W [Source:HGNC Symbol;Acc:HGNC:21488]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016363//nuclear matrix"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007059//chromosome segregation;GO:0034080//CENP-A containing nucleosome assembly;GO:0051276//chromosome organization;GO:0051301//cell division;GO:0051382//kinetochore assembly	--
ENSG00000203772	0.317	0.308	0.154	0.142	0.109	0.095	20.97	20.06	7.4	6.83	5.98	4.49	SPRN	shadow of prion protein [Source:HGNC Symbol;Acc:HGNC:16871]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031982//vesicle	GO:0003676//nucleic acid binding	GO:0006606//protein import into nucleus	--
ENSG00000203778	17.887	17.293	18.327	16.535	13.568	14.005	346	335	259	210	225	194	FAM229B	family with sequence similarity 229 member B [Source:HGNC Symbol;Acc:HGNC:33858]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000203780	5.221	4.953	3.138	1.395	1.616	1.919	107	102	53	20	36	29	FANK1	fibronectin type III and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:23527]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097546//ciliary base	GO:0005515//protein binding	"GO:0042981//regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity"	--
ENSG00000203782	0	0	0	0	0	0	0	0	0	0	0	0	LORICRIN	loricrin cornified envelope precursor protein [Source:HGNC Symbol;Acc:HGNC:6663]	-	-	-	-	GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0007010//cytoskeleton organization;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000203783	0	0	0	0	0	0	0	0	0	0	0	0	PRR9	proline rich 9 [Source:HGNC Symbol;Acc:HGNC:32057]	-	-	-	-	-	-	-	--
ENSG00000203784	0	0	0	0	0	0	0	0	0	0	0	0	LELP1	late cornified envelope like proline rich 1 [Source:HGNC Symbol;Acc:HGNC:32046]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000203785	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2E	small proline rich protein 2E [Source:HGNC Symbol;Acc:HGNC:11265]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0031424//keratinization	--
ENSG00000203786	0	0	0	0	0	0	0	0	0	0	0	0	KPRP	keratinocyte proline rich protein [Source:HGNC Symbol;Acc:HGNC:31823]	-	-	-	-	GO:0005737//cytoplasm;GO:0070062//extracellular exosome	GO:0005515//protein binding	-	--
ENSG00000203791	2.894	2.556	4.12	3.318	2.774	3.355	122.09	107.2	132.4	81.19	96.68	87.41	EEF1AKMT2	EEF1A lysine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:33787]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0043231//intracellular membrane-bounded organelle	GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0006479//protein methylation;GO:0018022//peptidyl-lysine methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation	--
ENSG00000203795	0	0	0	0	0	0	0	0	0	0	0	0	FAM24A	family with sequence similarity 24 member A [Source:HGNC Symbol;Acc:HGNC:23470]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000203797	2.177	1.936	1.971	0.852	1.45	0.642	95	83	62	27	53	20	DDO	D-aspartate oxidase [Source:HGNC Symbol;Acc:HGNC:2727]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko04146//Peroxisome;ko00250//Alanine, aspartate and glutamate metabolism;ko00470//D-Amino acid metabolism"	K00272;K00272;K00272;K00272	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0003884//D-amino-acid oxidase activity;GO:0005515//protein binding;GO:0008445//D-aspartate oxidase activity;GO:0016491//oxidoreductase activity;GO:0071949//FAD binding	GO:0006520//cellular amino acid metabolic process;GO:0006531//aspartate metabolic process;GO:0006533//aspartate catabolic process;GO:0007320//insemination;GO:0007625//grooming behavior;GO:0019478//D-amino acid catabolic process;GO:0042445//hormone metabolic process;GO:0046416//D-amino acid metabolic process	--
ENSG00000203805	2.537	2.192	1.793	3.124	2.789	3.142	182	158	95	166	169	164	PLPP4	phospholipid phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:23531]	Metabolism;Metabolism	Lipid metabolism;Lipid metabolism	ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism	K18693;K18693	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000810//diacylglycerol diphosphate phosphatase activity;GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding	GO:0001835//blastocyst hatching;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0046839//phospholipid dephosphorylation;GO:0090279//regulation of calcium ion import	--
ENSG00000203811	0	0	0	0	0	0	0	0	0	0	0	0	H3C14	H3 clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:20503]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly	--
ENSG00000203814	0.294	0.048	0	0	0	0.066	3	1	0	0	0	1	H2BC18	H2B clustered histone 18 [Source:HGNC Symbol;Acc:HGNC:24700]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000203837	0.081	0.02	0	0	0.024	0.028	4	1	0	0	1	1	PNLIPRP3	pancreatic lipase related protein 3 [Source:HGNC Symbol;Acc:HGNC:23492]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism	K14076;K14076	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004806//triglyceride lipase activity;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process	--
ENSG00000203852	0	0	0	0.377	0	0	0	0	0	3	0	0	H3C15	H3 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:20505]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly	--
ENSG00000203857	0.201	0.033	0.078	0.136	1.097	0.997	6	1	2	3	19	7	HSD3B1	"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5217]"	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Endocrine system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K00070;K00070;K00070;K00070;K00070;K00070	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge	"GO:0000253//3-keto sterol reductase activity;GO:0003824//catalytic activity;GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0004769//steroid delta-isomerase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016853//isomerase activity;GO:0047024//5alpha-androstane-3beta,17beta-diol dehydrogenase activity;GO:0102176//cycloeucalenone reductase activity;GO:0102294//cholesterol dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008152//metabolic process;GO:0008202//steroid metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0021766//hippocampus development;GO:0051412//response to corticosterone	--
ENSG00000203859	0	0	0	0	0.034	0	0	0	0	0	1	0	HSD3B2	"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 [Source:HGNC Symbol;Acc:HGNC:5218]"	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Endocrine system;Lipid metabolism;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis	K00070;K00070;K00070;K00070;K00070;K00070	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045171//intercellular bridge	"GO:0003824//catalytic activity;GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0004769//steroid delta-isomerase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016853//isomerase activity;GO:0102294//cholesterol dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0008152//metabolic process;GO:0008207//C21-steroid hormone metabolic process;GO:0021766//hippocampus development;GO:0051412//response to corticosterone	--
ENSG00000203867	0.251	0.243	0.206	0.205	0.047	0.164	38	37	23	23	6	18	RBM20	RNA binding motif protein 20 [Source:HGNC Symbol;Acc:HGNC:27424]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding	GO:0006397//mRNA processing;GO:0007507//heart development;GO:0008380//RNA splicing;GO:0033120//positive regulation of RNA splicing;GO:0043484//regulation of RNA splicing	--
ENSG00000203870	0	0	0	0	0	0	0	0	0	0	0	0	SMIM9	small integral membrane protein 9 [Source:HGNC Symbol;Acc:HGNC:41915]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000203872	0.072	0.124	0.049	0	0.042	0.163	2	4	1	0	1	4	C6orf163	chromosome 6 open reading frame 163 [Source:HGNC Symbol;Acc:HGNC:21403]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000203877	0	0	0	0.24	0	0.127	0	0	0	2	0	1	RIPPLY2	ripply transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:21390]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001503//ossification;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0007368//determination of left/right symmetry;GO:0009798//axis specification;GO:0009880//embryonic pattern specification;GO:0010468//regulation of gene expression;GO:0032525//somite rostral/caudal axis specification;GO:0036342//post-anal tail morphogenesis;GO:0060349//bone morphogenesis	--
ENSG00000203879	57.825	57.095	65.054	62.35	60.137	55.85	2646	2624	2147	2056	2293	1794	GDI1	GDP dissociation inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:4226]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030424//axon;GO:0030496//midbody;GO:0032991//protein-containing complex;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043209//myelin sheath	GO:0005092//GDP-dissociation inhibitor activity;GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0032482//Rab protein signal transduction;GO:0045773//positive regulation of axon extension;GO:0050771//negative regulation of axonogenesis;GO:0050790//regulation of catalytic activity;GO:0051592//response to calcium ion;GO:0090315//negative regulation of protein targeting to membrane	--
ENSG00000203880	47.908	42.581	48.735	50.77	52.767	55.489	2702	2554	2065	2157	2349	2144	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:15882]	-	-	-	-	GO:0005737//cytoplasm	GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;GO:0005515//protein binding	GO:0006464//cellular protein modification process;GO:0006479//protein methylation;GO:0006807//nitrogen compound metabolic process;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000203883	0.026	0.052	0	0	0	0.071	1	2	0	0	0	2	SOX18	SRY-box transcription factor 18 [Source:HGNC Symbol;Acc:HGNC:11194]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001525//angiogenesis;GO:0001568//blood vessel development;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0001942//hair follicle development;GO:0001944//vasculature development;GO:0001945//lymph vessel development;GO:0001946//lymphangiogenesis;GO:0001947//heart looping;GO:0003151//outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007507//heart development;GO:0009653//anatomical structure morphogenesis;GO:0022405//hair cycle process;GO:0030154//cell differentiation;GO:0035050//embryonic heart tube development;GO:0043534//blood vessel endothelial cell migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048469//cell maturation;GO:0048866//stem cell fate specification;GO:0060214//endocardium formation;GO:0060836//lymphatic endothelial cell differentiation;GO:0060956//endocardial cell differentiation;GO:0061028//establishment of endothelial barrier;GO:0072091//regulation of stem cell proliferation"	HMG
ENSG00000203896	0.548	0.557	0.879	0.559	0.766	0.223	10.9	11.83	12.3	6	13.71	2.97	LIME1	Lck interacting transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:26016]	-	-	-	-	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019815//B cell receptor complex	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043405//regulation of MAP kinase activity;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:1901222//regulation of NIK/NF-kappaB signaling	--
ENSG00000203907	0	0	0	0	0	0	0	0	0	0	0	0	OOEP	oocyte expressed protein [Source:HGNC Symbol;Acc:HGNC:21382]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0032991//protein-containing complex;GO:0045179//apical cortex;GO:0106333//subcortical maternal complex;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0008150//biological_process;GO:0009880//embryonic pattern specification;GO:0031297//replication fork processing;GO:0032880//regulation of protein localization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0045836//positive regulation of meiotic nuclear division;GO:0051293//establishment of spindle localization;GO:0051302//regulation of cell division;GO:0070201//regulation of establishment of protein localization;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000203908	0.046	0	0.063	0.063	0	0	1	0	1	1	0	0	KHDC3L	"KH domain containing 3 like, subcortical maternal complex member [Source:HGNC Symbol;Acc:HGNC:33699]"	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0032991//protein-containing complex;GO:0045179//apical cortex;GO:0106333//subcortical maternal complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0031297//replication fork processing;GO:0032880//regulation of protein localization;GO:0040019//positive regulation of embryonic development;GO:0043066//negative regulation of apoptotic process;GO:0050769//positive regulation of neurogenesis;GO:0051656//establishment of organelle localization;GO:1900006//positive regulation of dendrite development;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000203909	0	0	0	0	0	0	0	0	0	0	0	0	DPPA5	developmental pluripotency associated 5 [Source:HGNC Symbol;Acc:HGNC:19201]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003729//mRNA binding	GO:0010468//regulation of gene expression	--
ENSG00000203910	0	0	0	0	0	0	0	0	0	0	0	0	C1orf146	chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032]	-	-	-	-	GO:0005694//chromosome	-	GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0051321//meiotic cell cycle	--
ENSG00000203923	0	0	0	0	0	0	0	0	0	0	0	0	SPANXN1	SPANX family member N1 [Source:HGNC Symbol;Acc:HGNC:33174]	-	-	-	-	-	-	-	--
ENSG00000203926	0	0	0	0	0	0	0	0	0	0	0	0	SPANXA2	SPANX family member A2 [Source:HGNC Symbol;Acc:HGNC:14328]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007283//spermatogenesis	--
ENSG00000203933	0	0	0	0	0	0	0	0	0	0	0	0	CXorf66	chromosome X open reading frame 66 [Source:HGNC Symbol;Acc:HGNC:33743]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000203942	0	0.04	0	0	0	0	0	1	0	0	0	0	C10orf62	chromosome 10 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:23294]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000203943	0.737	0.671	0.552	0.291	1.208	0.977	20	16	10	7	22	21	SAMD13	sterile alpha motif domain containing 13 [Source:HGNC Symbol;Acc:HGNC:24582]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000203950	13.134	14.501	16.572	18.812	15.451	16.29	328	364	305.66	348	326	296	RTL8A	retrotransposon Gag like 8A [Source:HGNC Symbol;Acc:HGNC:24514]	-	-	-	-	GO:0005730//nucleolus	GO:0005515//protein binding	-	--
ENSG00000203952	2.373	1.623	2.151	2.492	1.862	2.234	102	70	69	74	65	65	CCDC160	coiled-coil domain containing 160 [Source:HGNC Symbol;Acc:HGNC:37286]	-	-	-	-	-	-	-	--
ENSG00000203963	0	0	0	0	0	0	0	0	0	0	0	0	C1orf141	chromosome 1 open reading frame 141 [Source:HGNC Symbol;Acc:HGNC:32044]	-	-	-	-	-	-	-	--
ENSG00000203965	4.405	4.118	3.417	2.839	2.594	3.255	199	187	114	95	99	107	EFCAB7	EF-hand calcium binding domain 7 [Source:HGNC Symbol;Acc:HGNC:29379]	Environmental Information Processing	Signal transduction	ko04340//Hedgehog signaling pathway	K23852	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane;GO:0098797//plasma membrane protein complex	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0042307//positive regulation of protein import into nucleus;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903569//positive regulation of protein localization to ciliary membrane	--
ENSG00000203970	0	0	0	0	0	0	0	0	0	0	0	0	DEFB110	defensin beta 110 [Source:HGNC Symbol;Acc:HGNC:18091]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000203972	0.084	0.066	0	0	0.052	0	1	3	0	0	2	0	GLYATL3	glycine-N-acyltransferase like 3 [Source:HGNC Symbol;Acc:HGNC:21349]	-	-	-	-	GO:0005739//mitochondrion	GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047961//glycine N-acyltransferase activity	GO:0006629//lipid metabolic process	--
ENSG00000203985	0.34	0.433	0.379	0.03	0.026	0.03	14	21	5	1	1	1	LDLRAD1	low density lipoprotein receptor class A domain containing 1 [Source:HGNC Symbol;Acc:HGNC:32069]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000203989	0	0	0	0	0	0	0	0	0	0	0	0	RHOXF2B	Rhox homeobox family member 2B [Source:HGNC Symbol;Acc:HGNC:33519]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010628//positive regulation of gene expression"	Homeobox
ENSG00000203995	0.026	0.065	0.015	0.018	0.087	0.054	2	6	1	1	6	3	ZYG11A	"zyg-11 family member A, cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:32058]"	-	-	-	-	GO:0031462//Cul2-RING ubiquitin ligase complex	-	-	--
ENSG00000204001	0	0	0	0	0	0	0	0	0	0	0	0	LCN8	lipocalin 8 [Source:HGNC Symbol;Acc:HGNC:27038]	-	-	-	-	GO:0005576//extracellular region	GO:0036094//small molecule binding	GO:0009725//response to hormone	--
ENSG00000204003	0	0	0	0	0	0	0	0	0	0	0	0	LCN6	novel protein	-	-	-	-	GO:0005576//extracellular region	GO:0036094//small molecule binding	-	--
ENSG00000204006	0	0	0	0	0	0	0	0	0	0	0	0	C1orf185	chromosome 1 open reading frame 185 [Source:HGNC Symbol;Acc:HGNC:28096]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204007	0	0	0	0	0	0	0	0	0	0	0	0	GLT6D1	glycosyltransferase 6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23671]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0030259//lipid glycosylation	--
ENSG00000204010	0	0	0	0	0	0	0	0	0	0	0	0	IFIT1B	interferon induced protein with tetratricopeptide repeats 1B [Source:HGNC Symbol;Acc:HGNC:23442]	Human Diseases	Infectious disease: viral	ko05160//Hepatitis C	K14217	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0009615//response to virus;GO:0050688//regulation of defense response to virus;GO:0051607//defense response to virus;GO:0071357//cellular response to type I interferon;GO:0071360//cellular response to exogenous dsRNA	--
ENSG00000204019	0	0	0	0	0	0	0	0	0	0	0	0	CT83	cancer/testis antigen 83 [Source:HGNC Symbol;Acc:HGNC:33494]	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204020	0	0	0	0	0	0	0	0	0	0	0	0	LIPN	lipase family member N [Source:HGNC Symbol;Acc:HGNC:23452]	-	-	-	-	GO:0005576//extracellular region;GO:0043231//intracellular membrane-bounded organelle	"GO:0004465//lipoprotein lipase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0070268//cornification	--
ENSG00000204021	0	0	0	0	0	0	0	0	0	0	0	0	LIPK	lipase family member K [Source:HGNC Symbol;Acc:HGNC:23444]	-	-	-	-	GO:0005576//extracellular region;GO:0043231//intracellular membrane-bounded organelle	"GO:0004465//lipoprotein lipase activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0070268//cornification	--
ENSG00000204022	0	0	0	0	0	0	0	0	0	0	0	0	LIPJ	lipase family member J [Source:HGNC Symbol;Acc:HGNC:21773]	-	-	-	-	GO:0043231//intracellular membrane-bounded organelle	"GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds"	GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process	--
ENSG00000204025	0	0.017	0	0.023	0.041	0	0	1	0	1	2	0	TRPC5OS	TRPC5 opposite strand [Source:HGNC Symbol;Acc:HGNC:40593]	-	-	-	-	-	-	-	--
ENSG00000204033	0.048	0.19	0.108	0.258	0.113	0.131	3	12	5	12	6	6	LRIT2	"leucine rich repeat, Ig-like and transmembrane domains 2 [Source:HGNC Symbol;Acc:HGNC:23443]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000204052	3.091	3.121	4.37	3.345	3.444	4.124	136	138	142	109	128	132	LRRC73	leucine rich repeat containing 73 [Source:HGNC Symbol;Acc:HGNC:21375]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204060	3.674	5.144	4.569	5.149	4.749	6.147	109	154	101	117	121	133	FOXO6	forkhead box O6 [Source:HGNC Symbol;Acc:HGNC:24814]	Human Diseases;Environmental Information Processing	Infectious disease: bacterial;Signal transduction	ko05131//Shigellosis;ko04068//FoxO signaling pathway	K17847;K17847	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007613//memory;GO:0060999//positive regulation of dendritic spine development"	Fork_head
ENSG00000204065	4.102	3.072	4.181	1.431	1.964	1.647	89	67	67	23	36	26	TCEAL5	transcription elongation factor A like 5 [Source:HGNC Symbol;Acc:HGNC:22282]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0050699//WW domain binding	-	--
ENSG00000204070	33.221	32.953	35.413	36.319	38.56	38.076	1433.54	1470.22	1171.53	1217.29	1318.9	1176.92	SYS1	SYS1 golgi trafficking protein [Source:HGNC Symbol;Acc:HGNC:16162]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	GO:0006895//Golgi to endosome transport;GO:0015031//protein transport;GO:0034067//protein localization to Golgi apparatus;GO:0043001//Golgi to plasma membrane protein transport	--
ENSG00000204071	0	0	0	0	0	0	0	0	0	0	0	0	TCEAL6	transcription elongation factor A like 6 [Source:HGNC Symbol;Acc:HGNC:24553]	-	-	-	-	GO:0005634//nucleus	GO:0050699//WW domain binding	-	--
ENSG00000204084	2.338	3.012	2.813	2.208	2.733	2.911	212	260	172	146	206	194	INPP5B	inositol polyphosphate-5-phosphatase B [Source:HGNC Symbol;Acc:HGNC:6077]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K01099;K01099;K01099	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane	"GO:0003824//catalytic activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0052745//inositol phosphate phosphatase activity"	GO:0001701//in utero embryonic development;GO:0006629//lipid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0007283//spermatogenesis;GO:0019637//organophosphate metabolic process;GO:0030317//flagellated sperm motility;GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0070613//regulation of protein processing	--
ENSG00000204086	0	0	0.084	0	0	0	0	0	2	0	0	0	RPA4	replication protein A4 [Source:HGNC Symbol;Acc:HGNC:30305]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03460//Fanconi anemia pathway;ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03430//Mismatch repair	K10741;K10741;K10741;K10741;K10741	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex;GO:0035861//site of double-strand break"	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0000077//DNA damage checkpoint signaling;GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000204099	0.143	0	0.232	0.137	0.05	0.136	7	0	3	4	2	4	NEU4	neuraminidase 4 [Source:HGNC Symbol;Acc:HGNC:21328]	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K12357;K12357;K12357	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019866//organelle inner membrane;GO:0031966//mitochondrial membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle	"GO:0004308//exo-alpha-sialidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052796//exo-alpha-(2->8)-sialidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006516//glycoprotein catabolic process;GO:0006629//lipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0010977//negative regulation of neuron projection development;GO:0016042//lipid catabolic process	--
ENSG00000204103	0.526	0.934	0.732	0.634	0.926	0.587	37	66	38	33	55	30	MAFB	MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K09036	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007379//segment specification;GO:0007423//sensory organ development;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0010467//gene expression;GO:0016485//protein processing;GO:0021571//rhombomere 5 development;GO:0021572//rhombomere 6 development;GO:0021599//abducens nerve formation;GO:0030216//keratinocyte differentiation;GO:0033077//T cell differentiation in thymus;GO:0035284//brain segmentation;GO:0042472//inner ear morphogenesis;GO:0045444//fat cell differentiation;GO:0045637//regulation of myeloid cell differentiation;GO:0045647//negative regulation of erythrocyte differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048538//thymus development;GO:0140467//integrated stress response signaling;GO:1903575//cornified envelope assembly"	TF_bZIP
ENSG00000204104	4.715	3.72	4.093	2.829	2.714	3.453	308	258	218	174	161	149	TRAF3IP1	TRAF3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:17861]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0030992//intraciliary transport particle B;GO:0035869//ciliary transition zone;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097542//ciliary tip;GO:0097546//ciliary base	GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0001738//morphogenesis of a polarized epithelium;GO:0001822//kidney development;GO:0001933//negative regulation of protein phosphorylation;GO:0030030//cell projection organization;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032480//negative regulation of type I interferon production;GO:0035720//intraciliary anterograde transport;GO:0042073//intraciliary transport;GO:0050687//negative regulation of defense response to virus;GO:0060271//cilium assembly;GO:0070507//regulation of microtubule cytoskeleton organization	--
ENSG00000204116	3.484	2.871	2.57	2.161	2.794	3.188	495	411	269	227	303	330	CHIC1	cysteine rich hydrophobic domain 1 [Source:HGNC Symbol;Acc:HGNC:1934]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	-	--
ENSG00000204120	20.982	18.271	15.492	13.121	14.1	13.11	1940	1783	1206	848	1093	985	GIGYF2	GRB10 interacting GYF protein 2 [Source:HGNC Symbol;Acc:HGNC:11960]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0043204//perikaryon;GO:1990635//proximal dendrite	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0070064//proline-rich region binding	GO:0007631//feeding behavior;GO:0008344//adult locomotory behavior;GO:0009791//post-embryonic development;GO:0016441//posttranscriptional gene silencing;GO:0017148//negative regulation of translation;GO:0021522//spinal cord motor neuron differentiation;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0035264//multicellular organism growth;GO:0044267//cellular protein metabolic process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0048873//homeostasis of number of cells within a tissue;GO:0050881//musculoskeletal movement;GO:0050885//neuromuscular process controlling balance;GO:0061157//mRNA destabilization	--
ENSG00000204128	1.873	1.48	2.015	1.829	1.808	2.155	141	112	112	102	115	118	C2orf72	chromosome 2 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:27418]	-	-	-	-	-	-	-	--
ENSG00000204130	3.697	2.417	2.509	1.889	2.647	2.403	287	196	163	123	173	152	RUFY2	RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12482	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0030100//regulation of endocytosis	--
ENSG00000204131	2.164	1.927	2.185	1.537	1.728	2.363	552	471	434	256	330	355	NHSL2	NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]	-	-	-	-	-	GO:0005515//protein binding	GO:0030154//cell differentiation	--
ENSG00000204136	0	0.042	0	0	0.044	0	0	3	0	0	1	0	GGTA1	glycoprotein alpha-galactosyltransferase 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:4253]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00601//Glycosphingolipid biosynthesis - lacto and neolacto series	K00743;K00743	GO:0005575//cellular_component;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna;GO:0032580//Golgi cisterna membrane	GO:0003674//molecular_function;GO:0016758//hexosyltransferase activity	GO:0005975//carbohydrate metabolic process;GO:0008150//biological_process;GO:0033580//protein galactosylation at cell surface;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000204138	10.704	9.856	11.761	9.137	8.796	9.721	867	882	662	533	652	613	PHACTR4	phosphatase and actin regulator 4 [Source:HGNC Symbol;Acc:HGNC:25793]	-	-	-	-	GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0003779//actin binding;GO:0008157//protein phosphatase 1 binding;GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity	GO:0001755//neural crest cell migration;GO:0001843//neural tube closure;GO:0007266//Rho protein signal transduction;GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0048484//enteric nervous system development;GO:0051726//regulation of cell cycle;GO:0061386//closure of optic fissure;GO:2001045//negative regulation of integrin-mediated signaling pathway	--
ENSG00000204140	0	0	0	0	0	0	0	0	0	0	0	0	CLPSL1	colipase like 1 [Source:HGNC Symbol;Acc:HGNC:21251]	-	-	-	-	GO:0005576//extracellular region	GO:0008047//enzyme activator activity	GO:0007586//digestion;GO:0016042//lipid catabolic process;GO:0032094//response to food;GO:0050790//regulation of catalytic activity	--
ENSG00000204147	1.875	1.827	1.557	1.184	1.255	1.986	117.54	112.5	86.48	73.12	101.15	127.69	ASAH2B	N-acylsphingosine amidohydrolase 2B [Source:HGNC Symbol;Acc:HGNC:23456]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K12349;K12349;K12349	GO:0005576//extracellular region	GO:0017040//N-acylsphingosine amidohydrolase activity	GO:0042759//long-chain fatty acid biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0046514//ceramide catabolic process	--
ENSG00000204149	1.343	1.588	1.772	1.884	1.378	2.276	75.03	89.3	69.63	75.54	62.15	90.14	AGAP6	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 [Source:HGNC Symbol;Acc:HGNC:23466]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000204152	2.074	2.157	1.622	1.681	1.853	2.078	107.65	113.77	62.21	56.96	77.63	78.74	TIMM23B	translocase of inner mitochondrial membrane 23 homolog B [Source:HGNC Symbol;Acc:HGNC:23581]	Organismal Systems	Aging	ko04212//Longevity regulating pathway - worm	K17794	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0003674//molecular_function;GO:0008320//protein transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0008150//biological_process;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000204160	4.959	5.271	4.681	6.162	5.437	3.562	319	288	176	273	294	242	ZDHHC18	zinc finger DHHC-type palmitoyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:20712]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation;GO:0034613//cellular protein localization	--
ENSG00000204161	0	0	0	0.074	0	0	0	0	0	2	0	0	TMEM273	transmembrane protein 273 [Source:HGNC Symbol;Acc:HGNC:27274]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204165	0	0	0	0	0	0	0	0	0	0	0	0	CXorf65	chromosome X open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:33713]	-	-	-	-	-	-	-	--
ENSG00000204172	1.204	0.96	0.796	1.363	1.554	0.82	59.61	47.78	29.11	50	65	29.53	AGAP9	"ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 [Source:HGNC Symbol;Acc:HGNC:23463]"	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12491	GO:0005634//nucleus	GO:0005096//GTPase activator activity;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000204174	0	0.027	0	0	0.095	0	0	1	0	0	3	0	NPY4R	neuropeptide Y receptor Y4 [Source:HGNC Symbol;Acc:HGNC:9329]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04206	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001602//pancreatic polypeptide receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0017046//peptide hormone binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000204175	0.213	0.129	0.063	0.232	0.246	0.272	41	25	9	33	40	38	GPRIN2	G protein regulated inducer of neurite outgrowth 2 [Source:HGNC Symbol;Acc:HGNC:23730]	-	-	-	-	GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0031175//neuron projection development	--
ENSG00000204176	0.515	0.42	0.316	0.25	0.179	0.457	53.03	51	27.75	24.7	18.92	41.62	SYT15	synaptotagmin 15 [Source:HGNC Symbol;Acc:HGNC:17167]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070382//exocytic vesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding	GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0071277//cellular response to calcium ion	--
ENSG00000204178	11.999	12.27	10.356	7.274	8.67	8.767	882	898	545	397	523	484	MACO1	macoilin 1 [Source:HGNC Symbol;Acc:HGNC:25572]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030867//rough endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0044306//neuron projection terminus;GO:0045202//synapse	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008017//microtubule binding	GO:0006935//chemotaxis;GO:0007420//brain development;GO:0023041//neuronal signal transduction	--
ENSG00000204179	0.422	0.407	0.465	0.628	0.204	0.594	15	15	6	16	8	11	PTPN20	protein tyrosine phosphatase non-receptor type 20 [Source:HGNC Symbol;Acc:HGNC:23423]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0034451//centriolar satellite	GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000204186	3.195	2.08	1.663	1.684	2.453	1.901	612	369	249	254	370	259	ZDBF2	zinc finger DBF-type containing 2 [Source:HGNC Symbol;Acc:HGNC:29313]	-	-	-	-	GO:0043229//intracellular organelle	GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0043045//DNA methylation involved in embryo development;GO:0071514//genetic imprinting	--
ENSG00000204193	0	0	0	0	0	0	0	0	0	0	0	0	TXNDC8	thioredoxin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:31454]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000204195	0	0	0	0	0	0	0	0	0	0	0	0	AWAT1	acyl-CoA wax alcohol acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23252]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047196//long-chain-alcohol O-fatty-acyltransferase activity;GO:0102966//arachidoyl-CoA:1-dodecanol O-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0010025//wax biosynthetic process;GO:0019369//arachidonic acid metabolic process	--
ENSG00000204209	13.849	13.602	15.836	13.383	15.06	13.091	737	729	627	528	668	508	DAXX	death domain associated protein [Source:HGNC Symbol;Acc:HGNC:2681]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Cellular Processes	Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Cell growth and death	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko04010//MAPK signaling pathway;ko05012//Parkinson disease;ko04210//Apoptosis	K02308;K02308;K02308;K02308;K02308;K02308	"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016605//PML body"	GO:0002039//p53 binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019901//protein kinase binding;GO:0030295//protein kinase activator activity;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042393//histone binding;GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0050681//androgen receptor binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140037//sumo-dependent protein binding;GO:0140416//transcription regulator inhibitor activity	"GO:0001934//positive regulation of protein phosphorylation;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0030521//androgen receptor signaling pathway;GO:0031396//regulation of protein ubiquitination;GO:0032147//activation of protein kinase activity;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0042981//regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0072738//cellular response to diamide;GO:1901216//positive regulation of neuron death;GO:1903936//cellular response to sodium arsenite"	--
ENSG00000204217	12.558	9.722	8.638	5.749	6.412	6.978	3116	2444	1597	1064	1356	1261	BMPR2	bone morphogenetic protein receptor type 2 [Source:HGNC Symbol;Acc:HGNC:1078]	Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Development and regeneration;Cancer: overview;Signal transduction;Cellular community - eukaryotes;Cardiovascular disease;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko04390//Hippo signaling pathway;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05418//Fluid shear stress and atherosclerosis;ko04350//TGF-beta signaling pathway	K04671;K04671;K04671;K04671;K04671;K04671;K04671	GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005905//clathrin-coated pit;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0043235//receptor complex;GO:0044214//spanning component of plasma membrane;GO:0044297//cell body	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016362//activin receptor activity, type II;GO:0016740//transferase activity;GO:0019211//phosphatase activator activity;GO:0030546//signaling receptor activator activity;GO:0036122//BMP binding;GO:0038023//signaling receptor activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0045296//cadherin binding;GO:0046872//metal ion binding;GO:0098821//BMP receptor activity;GO:1990782//protein tyrosine kinase binding"	GO:0001568//blood vessel development;GO:0001649//osteoblast differentiation;GO:0001707//mesoderm formation;GO:0001893//maternal placenta development;GO:0001935//endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001946//lymphangiogenesis;GO:0001974//blood vessel remodeling;GO:0002063//chondrocyte development;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003176//aortic valve development;GO:0003177//pulmonary valve development;GO:0003183//mitral valve morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0003197//endocardial cushion development;GO:0003252//negative regulation of cell proliferation involved in heart valve morphogenesis;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0009267//cellular response to starvation;GO:0009952//anterior/posterior pattern specification;GO:0010595//positive regulation of endothelial cell migration;GO:0010634//positive regulation of epithelial cell migration;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0014916//regulation of lung blood pressure;GO:0016310//phosphorylation;GO:0030166//proteoglycan biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0030501//positive regulation of bone mineralization;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0042127//regulation of cell population proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045778//positive regulation of ossification;GO:0045906//negative regulation of vasoconstriction;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0050790//regulation of catalytic activity;GO:0051148//negative regulation of muscle cell differentiation;GO:0060173//limb development;GO:0060350//endochondral bone morphogenesis;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060412//ventricular septum morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0060836//lymphatic endothelial cell differentiation;GO:0060840//artery development;GO:0060841//venous blood vessel development;GO:0061036//positive regulation of cartilage development;GO:0061298//retina vasculature development in camera-type eye;GO:0061626//pharyngeal arch artery morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0071773//cellular response to BMP stimulus;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0072577//endothelial cell apoptotic process;GO:1902731//negative regulation of chondrocyte proliferation;GO:1905314//semi-lunar valve development;GO:2000279//negative regulation of DNA biosynthetic process	--
ENSG00000204219	4.178	4.525	4.676	3.701	3.789	3.706	144	158	113	95	114	94	TCEA3	transcription elongation factor A3 [Source:HGNC Symbol;Acc:HGNC:11615]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006351//transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter"	--
ENSG00000204220	19.75	18.328	20.407	17.304	17.815	22.432	272	262	215	186	214	230	PFDN6	prefoldin subunit 6 [Source:HGNC Symbol;Acc:HGNC:4926]	-	-	-	-	GO:0005737//cytoplasm;GO:0016272//prefoldin complex;GO:0101031//chaperone complex;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0001540//amyloid-beta binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0050821//protein stabilization;GO:0051131//chaperone-mediated protein complex assembly;GO:1905907//negative regulation of amyloid fibril formation	--
ENSG00000204227	18.83	17.577	21.747	20.973	19.568	22.911	680	638	580	561	597	602	RING1	ring finger protein 1 [Source:HGNC Symbol;Acc:HGNC:10018]	-	-	-	-	GO:0000151//ubiquitin ligase complex;GO:0001739//sex chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0097027//ubiquitin-protein transferase activator activity	"GO:0006325//chromatin organization;GO:0009952//anterior/posterior pattern specification;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0035518//histone H2A monoubiquitination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048593//camera-type eye morphogenesis;GO:0050790//regulation of catalytic activity"	--
ENSG00000204228	6.76	9.524	10.891	13.524	11.331	9.97	137	194	163	203	194	147	HSD17B8	hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis	K13370;K13370;K13370;K13370	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0016020//membrane;GO:1990204//oxidoreductase complex	"GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0048038//quinone binding;GO:0070404//NADH binding;GO:0106386//(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008209//androgen metabolic process;GO:0008210//estrogen metabolic process;GO:0051290//protein heterotetramerization	--
ENSG00000204231	15.569	15.907	20.019	21.636	19.514	22.012	920.97	947	879.86	944	975	952.95	RXRB	retinoid X receptor beta [Source:HGNC Symbol;Acc:HGNC:10478]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Cancer: overview;Cardiovascular disease;Cancer: overview;Cancer: specific types;Endocrine system;Immune system;Endocrine system;Cancer: specific types;Endocrine system;Cancer: specific types;Endocrine system;Cancer: specific types	"ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko05226//Gastric cancer;ko04919//Thyroid hormone signaling pathway;ko04659//Th17 cell differentiation;ko04928//Parathyroid hormone synthesis, secretion and action;ko05222//Small cell lung cancer;ko03320//PPAR signaling pathway;ko05223//Non-small cell lung cancer;ko04920//Adipocytokine signaling pathway;ko05216//Thyroid cancer"	K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525;K08525	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009755//hormone-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0032526//response to retinoic acid;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043401//steroid hormone mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048384//retinoic acid receptor signaling pathway;GO:0048856//anatomical structure development;GO:0070564//positive regulation of vitamin D receptor signaling pathway"	RXR-like
ENSG00000204237	9.097	8.228	9.317	10.672	8.042	9.696	134	126	102	113	102	99	OXLD1	oxidoreductase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27901]	-	-	-	-	-	-	-	--
ENSG00000204246	0	0	0	0	0	0	0	0	0	0	0	0	OR13C3	olfactory receptor family 13 subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:14704]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204248	25.575	21.951	27.369	19.296	20.447	34.633	2592	2449	2007	1519	1823	2600	COL11A2	collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005592//collagen type XI trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005840//ribosome;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030674//protein-macromolecule adaptor activity;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0001894//tissue homeostasis;GO:0002062//chondrocyte differentiation;GO:0007605//sensory perception of sound;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0048705//skeletal system morphogenesis;GO:0051216//cartilage development;GO:0060021//roof of mouth development;GO:0060023//soft palate development	--
ENSG00000204252	0.056	0.138	0.132	0.056	0.033	0.153	4	10	7	3	2	8	HLA-DOA	"major histocompatibility complex, class II, DO alpha [Source:HGNC Symbol;Acc:HGNC:4936]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042613//MHC class II protein complex	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0045580//regulation of T cell differentiation;GO:0050870//positive regulation of T cell activation	--
ENSG00000204256	51.76	49.73	57.971	51.762	55.269	63.202	3437	3359	2684	2375	3075	2933	BRD2	bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003682//chromatin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0031493//nucleosomal histone binding;GO:0070577//lysine-acetylated histone binding	"GO:0001843//neural tube closure;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0010468//regulation of gene expression"	--
ENSG00000204257	2.514	3.204	2.81	2.739	2.951	2.728	57	72	46	46	56	45	HLA-DMA	"major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0042613//MHC class II protein complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000204262	19.646	19.233	13.19	9.631	12.05	10.242	2750	2730	1339	936	1436	1018	COL5A2	collagen type V alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2210]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K19721	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005588//collagen type V trimer;GO:0005592//collagen type XI trimer;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0046332//SMAD binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization;GO:0043588//skin development;GO:0048592//eye morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:1903225//negative regulation of endodermal cell differentiation	--
ENSG00000204264	17.838	18.539	21.043	27.698	22.83	29.089	451	484	392	527	491	541	PSMB8	proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K02740	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome;GO:1990111//spermatoproteasome complex"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0019882//antigen processing and presentation;GO:0030154//cell differentiation;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0045444//fat cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0052548//regulation of endopeptidase activity;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000204267	1.79	2.383	2.479	2.517	3.409	3.855	209.51	214.86	157.81	218.25	252.85	242.7	TAP2	"transporter 2, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:44]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Immune disease;Immune system;Membrane transport	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation;ko02010//ABC transporters	K05654;K05654;K05654;K05654;K05654;K05654;K05654;K05654	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030670//phagocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042824//MHC class I peptide loading complex;GO:0042825//TAP complex	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0015433//ABC-type peptide antigen transporter activity;GO:0015440//ABC-type peptide transporter activity;GO:0023029//MHC class Ib protein binding;GO:0042287//MHC protein binding;GO:0042288//MHC class I protein binding;GO:0042605//peptide antigen binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046872//metal ion binding;GO:0046978//TAP1 binding;GO:0046980//tapasin binding;GO:0140359//ABC-type transporter activity;GO:1904680//peptide transmembrane transporter activity	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002489//antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent;GO:0015031//protein transport;GO:0015833//peptide transport;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0046967//cytosol to endoplasmic reticulum transport;GO:0046968//peptide antigen transport;GO:0055085//transmembrane transport"	--
ENSG00000204271	3.389	3.764	3.168	3.763	3.754	4.591	258	238	164	186	236	239	SPIN3	spindlin family member 3 [Source:HGNC Symbol;Acc:HGNC:27272]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0035064//methylated histone binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007276//gamete generation"	--
ENSG00000204272	20.388	23.393	21.875	25.005	21.887	22.71	524	578	432	466	454	418	NBDY	negative regulator of P-body association [Source:HGNC Symbol;Acc:HGNC:50713]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006397//mRNA processing;GO:0010607//negative regulation of cytoplasmic mRNA processing body assembly	--
ENSG00000204278	7.791	9.067	7.298	8.747	7.655	10.116	335	380	235	292	291	325	TMEM235	transmembrane protein 235 [Source:HGNC Symbol;Acc:HGNC:27563]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	-	-	--
ENSG00000204279	0	0	0	0	0	0	0	0	0	0	0	0	PAGE3	PAGE family member 3 [Source:HGNC Symbol;Acc:HGNC:4110]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204287	1.718	1.903	2.537	1.581	4.39	1.019	44	49	48	30	95	19	HLA-DRA	"major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0001772//immunological synapse;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0030247//polysaccharide binding;GO:0032395//MHC class II receptor activity;GO:0042605//peptide antigen binding;GO:0042608//T cell receptor binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002469//myeloid dendritic cell antigen processing and presentation;GO:0002491//antigen processing and presentation of endogenous peptide antigen via MHC class II;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0032831//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0043382//positive regulation of memory T cell differentiation;GO:0045622//regulation of T-helper cell differentiation;GO:0050870//positive regulation of T cell activation;GO:0050890//cognition;GO:2000516//positive regulation of CD4-positive, alpha-beta T cell activation"	--
ENSG00000204290	0	0	0	0	0	0	0	0	0	0	0	0	BTNL2	butyrophilin like 2 [Source:HGNC Symbol;Acc:HGNC:1142]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding	GO:0001817//regulation of cytokine production;GO:0002376//immune system process;GO:0032743//positive regulation of interleukin-2 production;GO:0042102//positive regulation of T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway	--
ENSG00000204291	0.748	1.073	0.787	0.498	0.616	0.497	81	120	63	41	57	40	COL15A1	collagen type XV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2192]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K08135	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005582//collagen type XV trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0001525//angiogenesis;GO:0001886//endothelial cell morphogenesis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0030199//collagen fibril organization	--
ENSG00000204296	0	0	0	0	0.034	0	0	0	0	0	1	0	TSBP1	testis expressed basic protein 1 [Source:HGNC Symbol;Acc:HGNC:13922]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204300	0	0	0	0	0	0	0	0	0	0	0	0	TMEM225	transmembrane protein 225 [Source:HGNC Symbol;Acc:HGNC:32390]	-	-	-	-	GO:0002080//acrosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0010923//negative regulation of phosphatase activity	--
ENSG00000204301	0.214	0.256	0.416	0.261	0.237	0.314	30	36	43	27	28	32	NOTCH4	notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04330//Notch signaling pathway	K20996;K20996;K20996;K20996;K20996;K20996;K20996	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098791//Golgi apparatus subcompartment	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001709//cell fate determination;GO:0001763//morphogenesis of a branching structure;GO:0001837//epithelial to mesenchymal transition;GO:0001886//endothelial cell morphogenesis;GO:0001944//vasculature development;GO:0006355//regulation of transcription, DNA-templated;GO:0007219//Notch signaling pathway;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0007275//multicellular organism development;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030879//mammary gland development;GO:0042060//wound healing;GO:0045446//endothelial cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050793//regulation of developmental process;GO:0060354//negative regulation of cell adhesion molecule production;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin"	--
ENSG00000204304	10.033	9.537	10.816	10.159	11.31	11.553	672	642	535	504	640	563	PBX2	PBX homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8633]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007420//brain development;GO:0009887//animal organ morphogenesis;GO:0009954//proximal/distal pattern formation;GO:0030326//embryonic limb morphogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048666//neuron development"	Homeobox
ENSG00000204305	0.353	0.54	0.466	0.574	0.442	0.513	9	16	10	11	11	11	AGER	advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320]	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Immune system;Cardiovascular disease;Cardiovascular disease;Endocrine and metabolic disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04613//Neutrophil extracellular trap formation;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko04933//AGE-RAGE signaling pathway in diabetic complications	K19722;K19722;K19722;K19722;K19722;K19722	GO:0001650//fibrillar center;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0098794//postsynapse;GO:0110165//cellular anatomical entity	GO:0001540//amyloid-beta binding;GO:0004888//transmembrane signaling receptor activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0044877//protein-containing complex binding;GO:0050785//advanced glycation end-product receptor activity	"GO:0001666//response to hypoxia;GO:0001774//microglial cell activation;GO:0001914//regulation of T cell mediated cytotoxicity;GO:0001934//positive regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0007611//learning or memory;GO:0009611//response to wounding;GO:0010255//glucose mediated signaling pathway;GO:0014002//astrocyte development;GO:0031175//neuron projection development;GO:0032693//negative regulation of interleukin-10 production;GO:0032722//positive regulation of chemokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032735//positive regulation of interleukin-12 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042104//positive regulation of activated T cell proliferation;GO:0043507//positive regulation of JUN kinase activity;GO:0045056//transcytosis;GO:0046330//positive regulation of JNK cascade;GO:0048143//astrocyte activation;GO:0048167//regulation of synaptic plasticity;GO:0050727//regulation of inflammatory response;GO:0050930//induction of positive chemotaxis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051101//regulation of DNA binding;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0072657//protein localization to membrane;GO:0090647//modulation of age-related behavioral decline;GO:0150003//regulation of spontaneous synaptic transmission;GO:0150104//transport across blood-brain barrier;GO:1900271//regulation of long-term synaptic potentiation;GO:1900272//negative regulation of long-term synaptic potentiation;GO:1900453//negative regulation of long-term synaptic depression;GO:1900744//regulation of p38MAPK cascade;GO:1900745//positive regulation of p38MAPK cascade;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1903523//negative regulation of blood circulation;GO:1904472//positive regulation of endothelin production;GO:1904645//response to amyloid-beta;GO:1904646//cellular response to amyloid-beta;GO:2000439//positive regulation of monocyte extravasation;GO:2000514//regulation of CD4-positive, alpha-beta T cell activation;GO:2001200//positive regulation of dendritic cell differentiation"	--
ENSG00000204308	65.088	62.522	70.011	71.787	61.509	72.608	1508	1456	1198	1232	1204	1224	RNF5	ring finger protein 5 [Source:HGNC Symbol;Acc:HGNC:10068]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K10666	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0044322//endoplasmic reticulum quality control compartment	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009617//response to bacterium;GO:0010507//negative regulation of autophagy;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031648//protein destabilization;GO:0036503//ERAD pathway;GO:0044257//cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0071712//ER-associated misfolded protein catabolic process;GO:1904380//endoplasmic reticulum mannose trimming;GO:2000785//regulation of autophagosome assembly	--
ENSG00000204310	46.638	52.26	52.108	57.802	58.549	48.746	2070.92	2341.99	1725	1917.98	2232.96	1591.98	AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:324]	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K13509;K13509;K13509;K13509;K13509	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0001819//positive regulation of cytokine production;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process	--
ENSG00000204311	0.752	0.404	0.137	0.315	0.11	0.385	23	15	4	8	3	6	PJVK	pejvakin [Source:HGNC Symbol;Acc:HGNC:29502]	-	-	-	-	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030864//cortical actin cytoskeleton;GO:0035253//ciliary rootlet;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0120044//stereocilium base	-	GO:0000302//response to reactive oxygen species;GO:0000425//pexophagy;GO:0007605//sensory perception of sound;GO:0008219//cell death;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0097468//programmed cell death in response to reactive oxygen species;GO:0120045//stereocilium maintenance;GO:1900063//regulation of peroxisome organization	--
ENSG00000204314	0.196	0.111	0	0.113	0.223	0.259	7	4	0	3	7	7	PRRT1	proline rich transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:13943]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0045202//synapse;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding;GO:0030545//signaling receptor regulator activity;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0007611//learning or memory;GO:0008104//protein localization;GO:0034394//protein localization to cell surface;GO:0050808//synapse organization;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000204315	3.161	3.646	3.454	3.298	3.104	3.752	88	102	71	68	73	76	FKBPL	FKBP prolyl isomerase like [Source:HGNC Symbol;Acc:HGNC:13949]	-	-	-	-	GO:0005576//extracellular region;GO:0005829//cytosol	GO:0005515//protein binding	GO:0009314//response to radiation;GO:0045765//regulation of angiogenesis;GO:1905553//regulation of blood vessel branching	--
ENSG00000204316	19.916	21.793	22.4	26.265	26.179	27.275	561	617	466	548	623	559	MRPL38	mitochondrial ribosomal protein L38 [Source:HGNC Symbol;Acc:HGNC:14033]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0005515//protein binding	GO:0032543//mitochondrial translation	--
ENSG00000204323	1.757	2.34	3.331	1.765	2.121	2.351	66	87	81	48	69	57	SMIM5	small integral membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:40030]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000204334	0.08	0.239	0.217	0	0	0	1	3	2	0	0	0	ERICH2	glutamate rich 2 [Source:HGNC Symbol;Acc:HGNC:44395]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204335	0	0	0	0	0.056	0	0	0	0	0	2	0	SP5	Sp5 transcription factor [Source:HGNC Symbol;Acc:HGNC:14529]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0036342//post-anal tail morphogenesis;GO:0060349//bone morphogenesis;GO:0071407//cellular response to organic cyclic compound	zf-C2H2
ENSG00000204344	11.283	11.031	12.412	13.171	12.263	11.749	290.61	288.29	227.78	249.14	262.48	222.19	STK19	serine/threonine kinase 19 [Source:HGNC Symbol;Acc:HGNC:11398]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck	GO:0000166//nucleotide binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0031267//small GTPase binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0046579//positive regulation of Ras protein signal transduction	--
ENSG00000204345	0	0	0	0	0	0	0	0	0	0	0	0	CD300LD	CD300 molecule like family member d [Source:HGNC Symbol;Acc:HGNC:16848]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0002376//immune system process	--
ENSG00000204347	0.112	0	0	0.075	0.066	0.115	4	0	0	2	2	3	BTBD17	BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:33758]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0009615//response to virus;GO:0045071//negative regulation of viral genome replication	--
ENSG00000204348	7.307	8.488	9.227	9.324	8.846	10.083	229.39	267.71	214.25	217.86	233.52	229.86	DXO	decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0016787//hydrolase activity;GO:0034353//RNA pyrophosphohydrolase activity;GO:0046872//metal ion binding;GO:0110152//RNA NAD-cap (NAD-forming) hydrolase activity	GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006402//mRNA catabolic process;GO:0016070//RNA metabolic process;GO:0050779//RNA destabilization;GO:0071028//nuclear mRNA surveillance;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0110155//NAD-cap decapping	--
ENSG00000204351	18.113	19.273	20.825	19.704	19.624	18.434	1210	1280	1000	1025	1108	873	SKIV2L	Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:10898]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12599	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0055087//Ski complex	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity	"GO:0006401//RNA catabolic process;GO:0070478//nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"	--
ENSG00000204356	27.463	34.605	36.101	29.979	31.882	33.835	702	830	616	555	637	613	NELFE	negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016604//nuclear body;GO:0032021//NELF complex	GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900364//negative regulation of mRNA polyadenylation"	--
ENSG00000204361	0	0	0	0	0	0	0	0	0	0	0	0	NXPE2	neurexophilin and PC-esterase domain family member 2 [Source:HGNC Symbol;Acc:HGNC:26331]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000204363	0	0	0	0	0	0	0	0	0	0	0	0	SPANXN5	SPANX family member N5 [Source:HGNC Symbol;Acc:HGNC:33178]	-	-	-	-	-	-	-	--
ENSG00000204366	3.045	3.616	3.292	3.78	4.128	4.219	124	148	99	114	142	125	ZBTB12	zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000204370	29.366	24.864	30.369	26.394	26.171	29.735	800	691	622	543	611	600	SDHD	succinate dehydrogenase complex subunit D [Source:HGNC Symbol;Acc:HGNC:10683]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237	"GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0016020//membrane;GO:0016021//integral component of membrane"	GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0048039//ubiquinone binding	"GO:0006099//tricarboxylic acid cycle;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000204371	23.099	23.5	25.151	26.498	26.306	24.441	1900	1944	1532	1613	1835	1450	EHMT2	euchromatic histone lysine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:14129]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Aging;Amino acid metabolism	ko01100//Metabolic pathways;ko04211//Longevity regulating pathway;ko00310//Lysine degradation	K11420;K11420;K11420	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016607//nuclear speck	GO:0001222//transcription corepressor binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0046976//histone methyltransferase activity (H3-K27 specific);GO:0070742//C2H2 zinc finger domain binding;GO:1990841//promoter-specific chromatin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006275//regulation of DNA replication;GO:0006306//DNA methylation;GO:0006325//chromatin organization;GO:0009267//cellular response to starvation;GO:0016571//histone methylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation;GO:0034968//histone lysine methylation	--
ENSG00000204379	0	0	0	0	0	0	0	0	0	0	0	0	XAGE1A	X antigen family member 1A [Source:HGNC Symbol;Acc:HGNC:4111]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204381	43.283	41.925	34.396	24.848	28.776	25.47	1745	1730	1004	758	969	751	LAYN	layilin [Source:HGNC Symbol;Acc:HGNC:29471]	-	-	-	-	GO:0001726//ruffle;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0030246//carbohydrate binding	-	--
ENSG00000204382	0	0	0	0	0	0	0	0	0	0	0	0	XAGE1B	X antigen family member 1B [Source:HGNC Symbol;Acc:HGNC:25400]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204385	0.135	0.077	0.156	0.078	0.108	0.178	7	4	6	3	4	6	SLC44A4	solute carrier family 44 member 4 [Source:HGNC Symbol;Acc:HGNC:13941]	Human Diseases	Cancer: overview	ko05231//Choline metabolism in cancer	K15377	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0015220//choline transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0090422//thiamine pyrophosphate transmembrane transporter activity	GO:0006656//phosphatidylcholine biosynthetic process;GO:0008292//acetylcholine biosynthetic process;GO:0015871//choline transport;GO:0030307//positive regulation of cell growth;GO:0030974//thiamine pyrophosphate transmembrane transport;GO:0032475//otolith formation;GO:0035675//neuromast hair cell development;GO:0055085//transmembrane transport;GO:0061526//acetylcholine secretion	--
ENSG00000204386	36.196	40.427	39.445	44.302	42.356	44.169	2029	2219	1578	1821	2007	1778	NEU1	neuraminidase 1 [Source:HGNC Symbol;Acc:HGNC:7758]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00600//Sphingolipid metabolism;ko00511//Other glycan degradation	K01186;K01186;K01186;K01186	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0035580//specific granule lumen;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	"GO:0004308//exo-alpha-sialidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016997//alpha-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052796//exo-alpha-(2->8)-sialidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006629//lipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0008152//metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0016042//lipid catabolic process	--
ENSG00000204388	72.819	82.058	90.316	89.017	96.981	68.787	3801.73	4306.05	3482.45	3442.46	4277.6	2612.96	HSPA1B	heat shock protein family A (Hsp70) member 1B [Source:HGNC Symbol;Acc:HGNC:5233]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016234//inclusion body;GO:0016235//aggresome;GO:0016607//nuclear speck;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904813//ficolin-1-rich granule lumen;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0001664//G protein-coupled receptor binding;GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0044183//protein folding chaperone;GO:0047485//protein N-terminus binding;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0140545//protein disaggregase activity	GO:0006402//mRNA catabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0030308//negative regulation of cell growth;GO:0031396//regulation of protein ubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032757//positive regulation of interleukin-8 production;GO:0034599//cellular response to oxidative stress;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0043066//negative regulation of apoptotic process;GO:0045648//positive regulation of erythrocyte differentiation;GO:0046034//ATP metabolic process;GO:0046718//viral entry into host cell;GO:0050821//protein stabilization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060548//negative regulation of cell death;GO:0070370//cellular heat acclimation;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071383//cellular response to steroid hormone stimulus;GO:0090063//positive regulation of microtubule nucleation;GO:0090084//negative regulation of inclusion body assembly;GO:1901673//regulation of mitotic spindle assembly;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000204389	87.63	92.191	100.025	100.302	109.954	93.566	4362.27	4612.95	3677.55	3698.54	4624.4	3389.04	HSPA1A	heat shock protein family A (Hsp70) member 1A [Source:HGNC Symbol;Acc:HGNC:5232]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008180//COP9 signalosome;GO:0016234//inclusion body;GO:0016235//aggresome;GO:0016607//nuclear speck;GO:0031982//vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904813//ficolin-1-rich granule lumen;GO:1990904//ribonucleoprotein complex	GO:0000166//nucleotide binding;GO:0001618//virus receptor activity;GO:0001664//G protein-coupled receptor binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0031249//denatured protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0044183//protein folding chaperone;GO:0045296//cadherin binding;GO:0047485//protein N-terminus binding;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding;GO:0055131//C3HC4-type RING finger domain binding;GO:0097718//disordered domain specific binding;GO:0140545//protein disaggregase activity	GO:0006402//mRNA catabolic process;GO:0006986//response to unfolded protein;GO:0007041//lysosomal transport;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0030308//negative regulation of cell growth;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031396//regulation of protein ubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032757//positive regulation of interleukin-8 production;GO:0033120//positive regulation of RNA splicing;GO:0034599//cellular response to oxidative stress;GO:0034605//cellular response to heat;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0043066//negative regulation of apoptotic process;GO:0045648//positive regulation of erythrocyte differentiation;GO:0046034//ATP metabolic process;GO:0046718//viral entry into host cell;GO:0050821//protein stabilization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0060548//negative regulation of cell death;GO:0070370//cellular heat acclimation;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071383//cellular response to steroid hormone stimulus;GO:0090063//positive regulation of microtubule nucleation;GO:0090084//negative regulation of inclusion body assembly;GO:0097201//negative regulation of transcription from RNA polymerase II promoter in response to stress;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1901673//regulation of mitotic spindle assembly;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:1902380//positive regulation of endoribonuclease activity;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000204390	1.379	1.459	1.583	1.626	1.777	1.2	79	84	67	69	86	50	HSPA1L	heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Genetic Information Processing;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Transport and catabolism;Cardiovascular disease;Folding, sorting and degradation;Infectious disease: viral;Endocrine system;Transcription;Infectious disease: parasitic;Immune system;Aging;Infectious disease: bacterial"	ko04010//MAPK signaling pathway;ko05020//Prion disease;ko04144//Endocytosis;ko05417//Lipid and atherosclerosis;ko04141//Protein processing in endoplasmic reticulum;ko05162//Measles;ko04915//Estrogen signaling pathway;ko03040//Spliceosome;ko05145//Toxoplasmosis;ko04612//Antigen processing and presentation;ko04213//Longevity regulating pathway - multiple species;ko05134//Legionellosis	K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283;K03283	GO:0002199//zona pellucida receptor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0044297//cell body;GO:0072562//blood microparticle	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0044183//protein folding chaperone;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding	GO:0006986//response to unfolded protein;GO:0007339//binding of sperm to zona pellucida;GO:0016192//vesicle-mediated transport;GO:0034620//cellular response to unfolded protein;GO:0042026//protein refolding;GO:0051085//chaperone cofactor-dependent protein refolding;GO:1903955//positive regulation of protein targeting to mitochondrion	--
ENSG00000204392	17.138	18.113	21.455	18.965	18.49	16.218	305	324	282	250	278	210	LSM2	"LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:13940]"	Genetic Information Processing;Genetic Information Processing	"Transcription;Folding, sorting and degradation"	ko03040//Spliceosome;ko03018//RNA degradation	K12621;K12621	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005688//U6 snRNP;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071005//U2-type precatalytic spliceosome;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0120115//Lsm2-8 complex;GO:1990726//Lsm1-7-Pat1 complex	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0017070//U6 snRNA binding;GO:0031267//small GTPase binding	"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0008380//RNA splicing"	--
ENSG00000204394	18.453	20.049	18.774	20.723	19.399	17.258	1440	1557	1141	1222	1347	985	VARS1	valyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12651]	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01873	GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004832//valine-tRNA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006438//valyl-tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000204396	0.165	0.23	0.067	0.179	0.235	0.136	10	14	3	8	12	6	VWA7	von Willebrand factor A domain containing 7 [Source:HGNC Symbol;Acc:HGNC:13939]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000204397	0	0.09	0	0	0	0.149	0	1	0	0	0	1	CARD16	caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12806	GO:0032991//protein-containing complex;GO:0097179//protease inhibitor complex	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0030414//peptidase inhibitor activity;GO:0042802//identical protein binding;GO:0050700//CARD domain binding;GO:0089720//caspase binding	GO:0010466//negative regulation of peptidase activity;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032091//negative regulation of protein binding;GO:0032691//negative regulation of interleukin-1 beta production;GO:0042981//regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071222//cellular response to lipopolysaccharide;GO:0071456//cellular response to hypoxia;GO:0071494//cellular response to UV-C;GO:0097340//inhibition of cysteine-type endopeptidase activity	--
ENSG00000204403	0	0	0	0	0	0	0	0	0	0	0	0	CASP12	caspase 12 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:19004]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Genetic Information Processing;Human Diseases;Cellular Processes	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Immune system;Folding, sorting and degradation;Infectious disease: viral;Cell growth and death"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05020//Prion disease;ko04621//NOD-like receptor signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko05161//Hepatitis B;ko04210//Apoptosis	K04741;K04741;K04741;K04741;K04741;K04741;K04741;K04741	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097169//AIM2 inflammasome complex	GO:0008234//cysteine-type peptidase activity;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO:0006508//proteolysis;GO:0042981//regulation of apoptotic process;GO:0050727//regulation of inflammatory response;GO:0097190//apoptotic signaling pathway	--
ENSG00000204406	4.693	2.492	2.846	2.658	2.447	2.926	529	412	292	279	320	303	MBD5	methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:HGNC:20444]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0010369//chromocenter;GO:0030496//midbody;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0040014//regulation of multicellular organism growth;GO:0042593//glucose homeostasis;GO:0050795//regulation of behavior;GO:0060399//positive regulation of growth hormone receptor signaling pathway	--
ENSG00000204410	0.669	0.766	0.826	1.229	0.648	0.557	26	27.5	13.25	22	27.05	8.25	MSH5	mutS homolog 5 [Source:HGNC Symbol;Acc:HGNC:7328]	-	-	-	-	GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030983//mismatched DNA binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus;GO:0051026//chiasma assembly;GO:0051321//meiotic cell cycle	--
ENSG00000204414	0	0	0	0	0	0	0	0	0	0	0	0	CSHL1	chorionic somatomammotropin hormone like 1 [Source:HGNC Symbol;Acc:HGNC:2442]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031982//vesicle	GO:0005131//growth hormone receptor binding;GO:0005179//hormone activity;GO:0008083//growth factor activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0008150//biological_process;GO:0031667//response to nutrient levels;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0060396//growth hormone receptor signaling pathway	--
ENSG00000204420	0	0	0.027	0	0	0	0	0	1	0	0	0	MPIG6B	megakaryocyte and platelet inhibitory receptor G6b [Source:HGNC Symbol;Acc:HGNC:13937]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008201//heparin binding	GO:0007229//integrin-mediated signaling pathway;GO:0007596//blood coagulation;GO:0009968//negative regulation of signal transduction;GO:0030218//erythrocyte differentiation;GO:0030219//megakaryocyte differentiation;GO:0030220//platelet formation;GO:0035855//megakaryocyte development	--
ENSG00000204421	0	0	0	0	0	0	0	0	0	0	0	0	LY6G6C	lymphocyte antigen 6 family member G6C [Source:HGNC Symbol;Acc:HGNC:13936]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031225//anchored component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000204422	0	0	0	0	0	0	0	0	0	0	0	0	Ly6g6e	novel transcript	-	-	-	-	-	-	-	--
ENSG00000204424	0	0	0	0	0	0	0	0	0	0	0	0	LY6G6F	lymphocyte antigen 6 family member G6F [Source:HGNC Symbol;Acc:HGNC:13933]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031092//platelet alpha granule membrane	GO:0005515//protein binding	-	--
ENSG00000204427	12.046	14.37	13.923	15.797	15.109	14.833	484	574	397	464	524	424	ABHD16A	"abhydrolase domain containing 16A, phospholipase [Source:HGNC Symbol;Acc:HGNC:13921]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004620//phospholipase activity;GO:0005515//protein binding;GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity	GO:0006629//lipid metabolic process;GO:0006660//phosphatidylserine catabolic process;GO:0052651//monoacylglycerol catabolic process;GO:0098734//macromolecule depalmitoylation;GO:1905344//prostaglandin catabolic process	--
ENSG00000204428	0.413	0.353	0.85	1.274	0.5	0.418	8	7	10	17	8	6	LY6G5C	lymphocyte antigen 6 family member G5C [Source:HGNC Symbol;Acc:HGNC:13932]	-	-	-	-	GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0042802//identical protein binding	-	--
ENSG00000204435	91.982	91.025	90.381	100.917	96.267	105.561	1772.74	1763	1286.51	1440.42	1567	1480.29	CSNK2B	casein kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:2460]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Translation;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05020//Prion disease;ko04064//NF-kappa B signaling pathway;ko04310//Wnt signaling pathway;ko05162//Measles;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko03008//Ribosome biogenesis in eukaryotes;ko04137//Mitophagy - animal;ko04520//Adherens junction	K03115;K03115;K03115;K03115;K03115;K03115;K03115;K03115;K03115;K03115	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005956//protein kinase CK2 complex;GO:0031519//PcG protein complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0003682//chromatin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019887//protein kinase regulator activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016055//Wnt signaling pathway;GO:0016310//phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0033211//adiponectin-activated signaling pathway;GO:0034622//cellular protein-containing complex assembly;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0050790//regulation of catalytic activity;GO:0051101//regulation of DNA binding;GO:0061154//endothelial tube morphogenesis;GO:0080163//regulation of protein serine/threonine phosphatase activity	--
ENSG00000204438	15.635	15.161	17.917	13.762	13.969	19.62	352	405	305	296	305	305	GPANK1	G-patch domain and ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:13920]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0005515//protein binding	-	--
ENSG00000204439	7.676	8.468	9.261	10.441	8.556	10.736	395	438	352	398	372	402	C6orf47	chromosome 6 open reading frame 47 [Source:HGNC Symbol;Acc:HGNC:19076]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204442	0.38	0.311	0.247	0.119	0.283	0.136	73	60	35	17	46	19	NALF1	NALCN channel auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNC:33877]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0015275//stretch-activated, cation-selective, calcium channel activity"	GO:0098703//calcium ion import across plasma membrane	--
ENSG00000204444	1.768	1.421	1.557	3.488	1.771	2.243	26	21	17	38	22	24	APOM	apolipoprotein M [Source:HGNC Symbol;Acc:HGNC:13916]	-	-	-	-	GO:0005576//extracellular region;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0034365//discoidal high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle	GO:0005319//lipid transporter activity;GO:0005543//phospholipid binding;GO:0016209//antioxidant activity	GO:0006869//lipid transport;GO:0033344//cholesterol efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0034380//high-density lipoprotein particle assembly;GO:0034384//high-density lipoprotein particle clearance;GO:0034445//negative regulation of plasma lipoprotein oxidation;GO:0042157//lipoprotein metabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0098869//cellular oxidant detoxification	--
ENSG00000204449	0	0	0	0	0	0	0	0	0	0	0	0	TRIM49C	tripartite motif containing 49C [Source:HGNC Symbol;Acc:HGNC:38877]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000204450	0	0	0	0	0	0	0	0	0	0	0	0	TRIM64	tripartite motif containing 64 [Source:HGNC Symbol;Acc:HGNC:14663]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000204463	88.925	92.834	105.61	117.227	106.689	100.301	4982	5120	4209	4694	4819	4087	BAG6	BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0071818//BAT3 complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043022//ribosome binding;GO:0051787//misfolded protein binding;GO:0070628//proteasome binding;GO:1990381//ubiquitin-specific protease binding	GO:0001822//kidney development;GO:0002376//immune system process;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0006915//apoptotic process;GO:0007130//synaptonemal complex assembly;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0010498//proteasomal protein catabolic process;GO:0018393//internal peptidyl-lysine acetylation;GO:0030101//natural killer cell activation;GO:0030154//cell differentiation;GO:0030324//lung development;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031647//regulation of protein stability;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045861//negative regulation of proteolysis;GO:0045995//regulation of embryonic development;GO:0050821//protein stabilization;GO:0061857//endoplasmic reticulum stress-induced pre-emptive quality control;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071712//ER-associated misfolded protein catabolic process;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1904294//positive regulation of ERAD pathway;GO:1904378//maintenance of unfolded protein involved in ERAD pathway;GO:1904379//protein localization to cytosolic proteasome complex involved in ERAD pathway	--
ENSG00000204469	57.833	60.442	63.658	63.708	68.544	64.207	8241	8657	6698	6723	8250	6657	PRRC2A	proline rich coiled-coil 2A [Source:HGNC Symbol;Acc:HGNC:13918]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0030154//cell differentiation	--
ENSG00000204472	0	0	0	0	0.268	0	0	0	0	0	3	0	AIF1	allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352]	-	-	-	-	GO:0001726//ruffle;GO:0001891//phagocytic cup;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	"GO:0001774//microglial cell activation;GO:0001934//positive regulation of protein phosphorylation;GO:0006911//phagocytosis, engulfment;GO:0006954//inflammatory response;GO:0008284//positive regulation of cell population proliferation;GO:0010468//regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0014739//positive regulation of muscle hyperplasia;GO:0016601//Rac protein signal transduction;GO:0021549//cerebellum development;GO:0030041//actin filament polymerization;GO:0030046//parallel actin filament bundle assembly;GO:0030335//positive regulation of cell migration;GO:0031668//cellular response to extracellular stimulus;GO:0032722//positive regulation of chemokine production;GO:0032755//positive regulation of interleukin-6 production;GO:0032870//cellular response to hormone stimulus;GO:0034097//response to cytokine;GO:0034599//cellular response to oxidative stress;GO:0042102//positive regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048678//response to axon injury;GO:0050921//positive regulation of chemotaxis;GO:0051017//actin filament bundle assembly;GO:0051384//response to glucocorticoid;GO:0051602//response to electrical stimulus;GO:0051764//actin crosslink formation;GO:0071315//cellular response to morphine;GO:0071346//cellular response to interferon-gamma;GO:0071447//cellular response to hydroperoxide;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0071673//positive regulation of smooth muscle cell chemotaxis;GO:0071677//positive regulation of mononuclear cell migration;GO:0090026//positive regulation of monocyte chemotaxis;GO:0090271//positive regulation of fibroblast growth factor production;GO:0097178//ruffle assembly;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000406//positive regulation of T cell migration"	--
ENSG00000204475	0	0	0	0	0	0	0	0	0	0	0	0	NCR3	natural cytotoxicity triggering receptor 3 [Source:HGNC Symbol;Acc:HGNC:19077]	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K06743	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002376//immune system process;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0008037//cell recognition;GO:0030101//natural killer cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000204478	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF20	PRAME family member 20 [Source:HGNC Symbol;Acc:HGNC:25224]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204479	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF17	PRAME family member 17 [Source:HGNC Symbol;Acc:HGNC:29485]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204480	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF19	PRAME family member 19 [Source:HGNC Symbol;Acc:HGNC:24908]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204481	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF14	PRAME family member 14 [Source:HGNC Symbol;Acc:HGNC:13576]	-	-	-	-	-	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204482	0	0	0	0	0.113	0	0	0	0	0	1	0	LST1	leukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0000902//cell morphogenesis;GO:0002376//immune system process;GO:0006955//immune response;GO:0008360//regulation of cell shape;GO:0009653//anatomical structure morphogenesis;GO:0016358//dendrite development;GO:0050672//negative regulation of lymphocyte proliferation	--
ENSG00000204498	11.054	11.06	12.43	14.032	11.145	14.034	329	331	272	310	279	303	NFKBIL1	NFKB inhibitor like 1 [Source:HGNC Symbol;Acc:HGNC:7800]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000204501	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF15	PRAME family member 15 [Source:HGNC Symbol;Acc:HGNC:26764]	-	-	-	-	-	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204505	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF9	PRAME family member 9 [Source:HGNC Symbol;Acc:HGNC:27996]	-	-	-	-	-	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204510	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF7	PRAME family member 7 [Source:HGNC Symbol;Acc:HGNC:28415]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000204511	0	0	0	0	0	0	0	0	0	0	0	0	MCCD1	mitochondrial coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:20668]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000204514	8.463	10.745	7.287	7.223	10.262	8.709	233.42	254.84	161.6	158.72	197.13	141.21	ZNF814	zinc finger protein 814 [Source:HGNC Symbol;Acc:HGNC:33258]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204516	0.581	0.657	0.271	0.324	0.52	0.74	29	33	10	12	22	27	MICB	MHC class I polypeptide-related sequence B [Source:HGNC Symbol;Acc:HGNC:7091]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity	K07985;K07985	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046703//natural killer cell lectin-like receptor binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0006979//response to oxidative stress;GO:0009408//response to heat;GO:0019835//cytolysis;GO:0032526//response to retinoic acid;GO:0046629//gamma-delta T cell activation;GO:0050689//negative regulation of defense response to virus by host	--
ENSG00000204518	0.404	0.379	0.161	0	0.197	0.229	17	16	5	0	7	7	AADACL4	arylacetamide deacetylase like 4 [Source:HGNC Symbol;Acc:HGNC:32038]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	-	--
ENSG00000204519	2.421	2.346	2.245	1.784	2.539	2.236	229	223	156	125	193	132	ZNF551	zinc finger protein 551 [Source:HGNC Symbol;Acc:HGNC:25108]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204520	17.382	16.976	16.775	19.968	18.407	16.249	496	478	360	443	454	349	MICA	MHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:HGNC:7090]	Human Diseases;Organismal Systems	Infectious disease: viral;Immune system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity	K07985;K07985	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204524	0.733	0.984	1.273	0.651	0.529	1.122	150	171	133	67	76	106	ZNF805	zinc finger protein 805 [Source:HGNC Symbol;Acc:HGNC:23272]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204525	267.937	267.607	305.244	352.1	320.989	329.919	7744.32	7707.61	6389.97	7426.18	7761.32	6892.7	HLA-C	"major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0042612//MHC class I protein complex;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0046977//TAP binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002486//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0045087//innate immune response;GO:0045321//leukocyte activation;GO:0060333//interferon-gamma-mediated signaling pathway"	--
ENSG00000204531	0.046	0.045	0.029	0.038	0	0	1	1	1	1	0	0	POU5F1	POU class 5 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9221]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09367	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019955//cytokine binding;GO:0031625//ubiquitin protein ligase binding;GO:0035198//miRNA binding;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001714//endodermal cell fate specification;GO:0001824//blastocyst development;GO:0003130//BMP signaling pathway involved in heart induction;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009611//response to wounding;GO:0009653//anatomical structure morphogenesis;GO:0009786//regulation of asymmetric cell division;GO:0010468//regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0035019//somatic stem cell population maintenance;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060391//positive regulation of SMAD protein signal transduction;GO:0060795//cell fate commitment involved in formation of primary germ layer;GO:0060913//cardiac cell fate determination;GO:0060965//negative regulation of gene silencing by miRNA;GO:0090081//regulation of heart induction by regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090308//regulation of DNA methylation-dependent heterochromatin assembly;GO:1902894//negative regulation of pri-miRNA transcription by RNA polymerase II"	Pou
ENSG00000204532	0	0	0	0	0	0	0	0	0	0	0	0	ZSCAN5C	zinc finger and SCAN domain containing 5C [Source:HGNC Symbol;Acc:HGNC:34294]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000204536	4.458	5.205	6.059	5.994	4.354	4.512	201	200	146	146	137	142	CCHCR1	coiled-coil alpha-helical rod protein 1 [Source:HGNC Symbol;Acc:HGNC:13930]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006611//protein export from nucleus;GO:0030154//cell differentiation	--
ENSG00000204538	0	0	0	0	0	0	0	0	0	0	0	0	PSORS1C2	psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000204539	0.038	0.075	0.077	0	0	0	2	4	3	0	0	0	CDSN	corneodesmosin [Source:HGNC Symbol;Acc:HGNC:1802]	-	-	-	-	GO:0005576//extracellular region	-	GO:0043589//skin morphogenesis	--
ENSG00000204540	0	0	0	0.298	0	0	0	0	0	3	0	0	PSORS1C1	psoriasis susceptibility 1 candidate 1 [Source:HGNC Symbol;Acc:HGNC:17202]	-	-	-	-	-	-	-	--
ENSG00000204542	0	0	0	0	0	0	0	0	0	0	0	0	C6orf15	chromosome 6 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:13927]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0030198//extracellular matrix organization	--
ENSG00000204544	0	0	0	0	0	0	0	0	0	0	0	0	MUC21	"mucin 21, cell surface associated [Source:HGNC Symbol;Acc:HGNC:21661]"	-	-	-	-	GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007162//negative regulation of cell adhesion;GO:0022408//negative regulation of cell-cell adhesion	--
ENSG00000204548	0	0	0	0	0	0	0	0	0	0	0	0	DEFB121	defensin beta 121 [Source:HGNC Symbol;Acc:HGNC:18101]	-	-	-	-	GO:0005576//extracellular region	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000204560	12.308	11.771	13.391	9.163	10.147	10.767	733	758	568	475	602	546	DHX16	DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12813	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071005//U2-type precatalytic spliceosome	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000204564	4.711	4.453	5.154	5.37	6.155	7.928	125	121	109	118	147	152	C6orf136	chromosome 6 open reading frame 136 [Source:HGNC Symbol;Acc:HGNC:21301]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204568	26.623	23.948	28.67	32.822	30.818	31.329	772	698	614	705	755	661	MRPS18B	mitochondrial ribosomal protein S18B [Source:HGNC Symbol;Acc:HGNC:14516]	Human Diseases	Cancer: overview	ko05203//Viral carcinogenesis	K16174	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0030054//cell junction;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000204569	23.106	25.625	28.16	25.682	27.362	26.278	2162	2410	1946	1780	2163	1789	PPP1R10	protein phosphatase 1 regulatory subunit 10 [Source:HGNC Symbol;Acc:HGNC:9284]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0072357//PTW/PP1 phosphatase complex"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0046872//metal ion binding	GO:0006606//protein import into nucleus;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0032206//positive regulation of telomere maintenance;GO:0043086//negative regulation of catalytic activity;GO:1904290//negative regulation of mitotic DNA damage checkpoint	--
ENSG00000204571	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-11	keratin associated protein 5-11 [Source:HGNC Symbol;Acc:HGNC:23606]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000204572	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-10	keratin associated protein 5-10 [Source:HGNC Symbol;Acc:HGNC:23605]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000204574	17.388	17.703	18.096	12.975	14.592	15.546	1223	1221	920	681	839	798	ABCF1	ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0042788//polysomal ribosome	"GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008135//translation factor activity, RNA binding;GO:0008494//translation activator activity;GO:0043022//ribosome binding"	GO:0006412//translation;GO:0006413//translational initiation;GO:0006954//inflammatory response;GO:0045727//positive regulation of translation	--
ENSG00000204576	7.593	7.7	8.131	7.587	9.037	8.651	286	291	226	212	287	237	PRR3	proline rich 3 [Source:HGNC Symbol;Acc:HGNC:21149]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000204577	0	0	0	0	0.028	0.024	0	0	0	0	1	1	LILRB3	leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0032396//inhibitory MHC class I receptor activity;GO:0038023//signaling receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0045671//negative regulation of osteoclast differentiation	--
ENSG00000204580	49.55	53.983	45.459	43.161	49.168	47.635	3407	3729	2411	2249	2910	2465	DDR1	discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0038062//protein tyrosine kinase collagen receptor activity;GO:0046872//metal ion binding	"GO:0001558//regulation of cell growth;GO:0001952//regulation of cell-matrix adhesion;GO:0006468//protein phosphorylation;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007565//female pregnancy;GO:0007566//embryo implantation;GO:0007595//lactation;GO:0008285//negative regulation of cell population proliferation;GO:0010715//regulation of extracellular matrix disassembly;GO:0014909//smooth muscle cell migration;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033674//positive regulation of kinase activity;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0043583//ear development;GO:0044319//wound healing, spreading of cells;GO:0046777//protein autophosphorylation;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060749//mammary gland alveolus development;GO:0061302//smooth muscle cell-matrix adhesion;GO:0061564//axon development;GO:1990138//neuron projection extension"	--
ENSG00000204583	0	0	0	0	0	0	0	0	0	0	0	0	LRCOL1	leucine rich colipase like 1 [Source:HGNC Symbol;Acc:HGNC:44160]	-	-	-	-	GO:0005576//extracellular region	GO:0008047//enzyme activator activity	GO:0007586//digestion;GO:0016042//lipid catabolic process;GO:0032094//response to food;GO:0050790//regulation of catalytic activity	--
ENSG00000204590	13.453	12.802	12.914	16.58	15.392	18.176	1153	1072	874	990	1093	904	GNL1	G protein nucleolar 1 (putative) [Source:HGNC Symbol;Acc:HGNC:4413]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005525//GTP binding	GO:0002456//T cell mediated immunity;GO:0006974//cellular response to DNA damage stimulus;GO:0007165//signal transduction	--
ENSG00000204592	69.205	71.74	72.809	90.434	85.396	84.188	3657.53	3811.01	2842	3540.33	3813.01	3237.4	HLA-E	"major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0032398//MHC class Ib protein complex;GO:0042612//MHC class I protein complex;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0042288//MHC class I protein binding;GO:0042605//peptide antigen binding;GO:0042608//T cell receptor binding;GO:0046703//natural killer cell lectin-like receptor binding	"GO:0001815//positive regulation of antibody-dependent cellular cytotoxicity;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002476//antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002477//antigen processing and presentation of exogenous peptide antigen via MHC class Ib;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002519//natural killer cell tolerance induction;GO:0002639//positive regulation of immunoglobulin production;GO:0002715//regulation of natural killer cell mediated immunity;GO:0002717//positive regulation of natural killer cell mediated immunity;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0006955//immune response;GO:0019731//antibacterial humoral response;GO:0019882//antigen processing and presentation;GO:0032736//positive regulation of interleukin-13 production;GO:0032753//positive regulation of interleukin-4 production;GO:0032759//positive regulation of TRAIL production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0045087//innate immune response;GO:0045321//leukocyte activation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0060333//interferon-gamma-mediated signaling pathway;GO:2000566//positive regulation of CD8-positive, alpha-beta T cell proliferation;GO:2001187//positive regulation of CD8-positive, alpha-beta T cell activation"	--
ENSG00000204595	0	0	0	0	0	0	0	0	0	0	0	0	DPRX	divergent-paired related homeobox [Source:HGNC Symbol;Acc:HGNC:32166]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000204599	8.711	10.354	9.432	8.444	9.065	10.422	496	520	396	354	419	387	TRIM39	tripartite motif containing 39 [Source:HGNC Symbol;Acc:HGNC:10065]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007095//mitotic G2 DNA damage checkpoint signaling;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0050821//protein stabilization;GO:1902806//regulation of cell cycle G1/S phase transition;GO:2000059//negative regulation of ubiquitin-dependent protein catabolic process;GO:2001235//positive regulation of apoptotic signaling pathway	--
ENSG00000204604	14.827	8.25	8.052	5.526	7.421	6.906	581.6	384.1	283	238	315	282	ZNF468	zinc finger protein 468 [Source:HGNC Symbol;Acc:HGNC:33105]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204610	0	0	0	0	0	0	0	0	0	0	0	0	TRIM15	tripartite motif containing 15 [Source:HGNC Symbol;Acc:HGNC:16284]	-	-	-	-	GO:0005737//cytoplasm	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0007500//mesodermal cell fate determination;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0032481//positive regulation of type I interferon production;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1900246//positive regulation of RIG-I signaling pathway;GO:1901253//negative regulation of intracellular transport of viral material"	--
ENSG00000204611	2.678	3.844	2.553	1.566	1.892	2.085	214	204	147	99	144	131	ZNF616	zinc finger protein 616 [Source:HGNC Symbol;Acc:HGNC:28062]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204612	0	0	0	0	0	0	0	0	0	0	0	0	FOXB2	forkhead box B2 [Source:HGNC Symbol;Acc:HGNC:23315]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000204613	0	0	0	0	0	0	0	0	0	0	0	0	TRIM10	tripartite motif containing 10 [Source:HGNC Symbol;Acc:HGNC:10072]	-	-	-	-	GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008150//biological_process;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0030218//erythrocyte differentiation;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell	--
ENSG00000204614	0	0	0	0	0	0	0	0	0	0	0	0	TRIM40	tripartite motif containing 40 [Source:HGNC Symbol;Acc:HGNC:18736]	-	-	-	-	GO:0005737//cytoplasm;GO:0008385//IkappaB kinase complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0030308//negative regulation of cell growth;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0042177//negative regulation of protein catabolic process;GO:0045087//innate immune response;GO:0045116//protein neddylation;GO:1900181//negative regulation of protein localization to nucleus;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000204616	0	0	0	0	0	0	0	0	0	0	0	0	TRIM31	tripartite motif containing 31 [Source:HGNC Symbol;Acc:HGNC:16289]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0019076//viral release from host cell;GO:0032897//negative regulation of viral transcription;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity"	--
ENSG00000204618	0.509	0.253	0.251	0.396	0.469	0.572	22	11	8	12	17	18	RNF39	ring finger protein 39 [Source:HGNC Symbol;Acc:HGNC:18064]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0008150//biological_process;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000204619	34.428	39.573	37.345	39.437	38.841	37.56	1159	1338	928	983	1105	921	PPP1R11	protein phosphatase 1 regulatory inhibitor subunit 11 [Source:HGNC Symbol;Acc:HGNC:9285]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0016740//transferase activity;GO:0061630//ubiquitin protein ligase activity	GO:0001818//negative regulation of cytokine production;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000204624	0.128	0.113	0.037	0	0.054	0.025	14	10	3	0	5	2	DISP3	dispatched RND transporter family member 3 [Source:HGNC Symbol;Acc:HGNC:29251]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane	GO:0003674//molecular_function	GO:0006629//lipid metabolic process;GO:0007224//smoothened signaling pathway;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030154//cell differentiation;GO:0032368//regulation of lipid transport;GO:0042632//cholesterol homeostasis;GO:0045665//negative regulation of neuron differentiation;GO:0045834//positive regulation of lipid metabolic process;GO:2000179//positive regulation of neural precursor cell proliferation	--
ENSG00000204628	723.323	722.436	713.894	837.736	769.486	717.414	16093	16388	11792	13784	14112	11931	RACK1	receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399]	Human Diseases	Infectious disease: viral	ko05162//Measles	K14753	GO:0001891//phagocytic cup;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0030425//dendrite;GO:0030496//midbody;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0044297//cell body;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:1990630//IRE1-RACK1-PP2A complex	GO:0003723//RNA binding;GO:0005080//protein kinase C binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008200//ion channel inhibitor activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0030332//cyclin binding;GO:0030971//receptor tyrosine kinase binding;GO:0035591//signaling adaptor activity;GO:0042169//SH2 domain binding;GO:0042803//protein homodimerization activity;GO:0043022//ribosome binding;GO:0045296//cadherin binding;GO:0051434//BH3 domain binding;GO:0060090//molecular adaptor activity	GO:0001934//positive regulation of protein phosphorylation;GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007049//cell cycle;GO:0007369//gastrulation;GO:0010629//negative regulation of gene expression;GO:0016567//protein ubiquitination;GO:0017148//negative regulation of translation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030308//negative regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0031334//positive regulation of protein-containing complex assembly;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032880//regulation of protein localization;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0040008//regulation of growth;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0043065//positive regulation of apoptotic process;GO:0043473//pigmentation;GO:0043547//positive regulation of GTPase activity;GO:0045879//negative regulation of smoothened signaling pathway;GO:0048511//rhythmic process;GO:0050765//negative regulation of phagocytosis;GO:0051302//regulation of cell division;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0051726//regulation of cell cycle;GO:0051898//negative regulation of protein kinase B signaling;GO:0051901//positive regulation of mitochondrial depolarization;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0071333//cellular response to glucose stimulus;GO:0071363//cellular response to growth factor stimulus;GO:0072344//rescue of stalled ribosome;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response;GO:1903208//negative regulation of hydrogen peroxide-induced neuron death;GO:2000114//regulation of establishment of cell polarity;GO:2000543//positive regulation of gastrulation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000204632	0.11	0.225	0	0.148	0.043	0.078	3	4	0	3	1	1	HLA-G	"major histocompatibility complex, class I, G [Source:HGNC Symbol;Acc:HGNC:4964]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031527//filopodium membrane;GO:0031901//early endosome membrane;GO:0033106//cis-Golgi network membrane;GO:0042612//MHC class I protein complex;GO:0042995//cell projection;GO:0055038//recycling endosome membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0042610//CD8 receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0002376//immune system process;GO:0002451//peripheral B cell tolerance induction;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002476//antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002645//positive regulation of tolerance induction;GO:0002666//positive regulation of T cell tolerance induction;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0006968//cellular defense response;GO:0016525//negative regulation of angiogenesis;GO:0032735//positive regulation of interleukin-12 production;GO:0042130//negative regulation of T cell proliferation;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0050777//negative regulation of immune response;GO:0051898//negative regulation of protein kinase B signaling;GO:0060907//positive regulation of macrophage cytokine production;GO:0070207//protein homotrimerization;GO:0070317//negative regulation of G0 to G1 transition;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000774//positive regulation of cellular senescence;GO:2001199//negative regulation of dendritic cell differentiation	--
ENSG00000204634	1.22	1.19	1.026	1.17	1.648	1.394	106	101	62	72	110	85	TBC1D8	TBC1 domain family member 8 [Source:HGNC Symbol;Acc:HGNC:17791]	-	-	-	-	GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0008015//blood circulation;GO:0008284//positive regulation of cell population proliferation;GO:0050790//regulation of catalytic activity;GO:0090630//activation of GTPase activity	--
ENSG00000204640	0	0	0	0	0	0	0	0	0	0	0	0	NMS	neuromedin S [Source:HGNC Symbol;Acc:HGNC:32203]	-	-	-	-	GO:0005576//extracellular region	GO:0001664//G protein-coupled receptor binding	GO:0007218//neuropeptide signaling pathway;GO:0045475//locomotor rhythm	--
ENSG00000204642	13.262	12.427	16.324	18.792	17.735	17.093	356	339	324	366	404	334	HLA-F	"major histocompatibility complex, class I, F [Source:HGNC Symbol;Acc:HGNC:4963]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0032398//MHC class Ib protein complex;GO:0042612//MHC class I protein complex;GO:0055038//recycling endosome membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0042605//peptide antigen binding;GO:0046978//TAP1 binding;GO:0046979//TAP2 binding;GO:0071889//14-3-3 protein binding	GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002476//antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002477//antigen processing and presentation of exogenous peptide antigen via MHC class Ib;GO:0002725//negative regulation of T cell cytokine production;GO:0002728//negative regulation of natural killer cell cytokine production;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0043322//negative regulation of natural killer cell degranulation;GO:0043323//positive regulation of natural killer cell degranulation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:1901215//negative regulation of neuron death	--
ENSG00000204644	0.06	0.12	0.041	0.122	0.178	0.064	2	4	1	3	5	2	ZFP57	ZFP57 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:18791]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0043045//DNA methylation involved in embryo development"	zf-C2H2
ENSG00000204653	0	0	0	0	0	0	0	0	0	0	0	0	ASPDH	aspartate dehydrogenase domain containing [Source:HGNC Symbol;Acc:HGNC:33856]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00760//Nicotinate and nicotinamide metabolism	K06989;K06989	-	GO:0016491//oxidoreductase activity;GO:0033735//aspartate dehydrogenase activity;GO:0050661//NADP binding;GO:0106351//aspartate dehydrogenase NAD activity;GO:0106352//aspartate dehydrogenase NADP activity	GO:0009435//NAD biosynthetic process;GO:0019363//pyridine nucleotide biosynthetic process	--
ENSG00000204655	19.604	17.201	18.032	24.119	22.715	31.54	736	664	516	694	712	867	MOG	myelin oligodendrocyte glycoprotein [Source:HGNC Symbol;Acc:HGNC:7197]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0001817//regulation of cytokine production;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0046718//viral entry into host cell;GO:0050852//T cell receptor signaling pathway	--
ENSG00000204657	0	0	0	0	0	0	0	0	0	0	0	0	OR2H2	olfactory receptor family 2 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8253]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0006952//defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0007618//mating;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204659	0.278	0.166	0	0.165	0.2	0	5	3	0	2.2	3.04	0	CBY3	chibby family member 3 [Source:HGNC Symbol;Acc:HGNC:33278]	-	-	-	-	-	-	-	--
ENSG00000204669	0	0	0	0	0	0	0	0	0	0	0	0	C9orf57	chromosome 9 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:27037]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000204671	0	0	0	0	0	0	0	0	0	0	0	0	IL31	interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22631	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005515//protein binding	GO:0002376//immune system process;GO:0007165//signal transduction	--
ENSG00000204673	30.233	30.861	34.652	40.733	38.465	35.635	1397	1445	1222	1408	1484	1288	AKT1S1	AKT1 substrate 1 [Source:HGNC Symbol;Acc:HGNC:28426]	Human Diseases;Organismal Systems;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Environmental adaptation;Signal transduction;Transport and catabolism;Signal transduction;Aging;Aging	ko05131//Shigellosis;ko04714//Thermogenesis;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko04213//Longevity regulating pathway - multiple species	K16184;K16184;K16184;K16184;K16184;K16184;K16184	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031931//TORC1 complex	GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity;GO:0032007//negative regulation of TOR signaling;GO:0042981//regulation of apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0045792//negative regulation of cell size;GO:0048011//neurotrophin TRK receptor signaling pathway	--
ENSG00000204681	1.75	1.516	1.495	2.037	2.092	2.61	129	108	88	117	131	147	GABBR1	gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070]	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine system;Substance dependence;Nervous system;Sensory system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04915//Estrogen signaling pathway;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko04742//Taste transduction;ko04929//GnRH secretion	K04615;K04615;K04615;K04615;K04615;K04615;K04615	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0030673//axolemma;GO:0031966//mitochondrial membrane;GO:0038037//G protein-coupled receptor dimeric complex;GO:0038039//G protein-coupled receptor heterodimeric complex;GO:0042734//presynaptic membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0043198//dendritic shaft;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097060//synaptic membrane;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098793//presynapse;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse;GO:0099055//integral component of postsynaptic membrane;GO:0099056//integral component of presynaptic membrane;GO:0110165//cellular anatomical entity;GO:1902710//GABA receptor complex;GO:1902712//G protein-coupled GABA receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004965//G protein-coupled GABA receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0099579//G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential;GO:1990430//extracellular matrix protein binding	"GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0014048//regulation of glutamate secretion;GO:0014049//positive regulation of glutamate secretion;GO:0014053//negative regulation of gamma-aminobutyric acid secretion;GO:0032811//negative regulation of epinephrine secretion;GO:0033602//negative regulation of dopamine secretion;GO:0035094//response to nicotine;GO:0045471//response to ethanol;GO:0050805//negative regulation of synaptic transmission;GO:0051932//synaptic transmission, GABAergic;GO:0060078//regulation of postsynaptic membrane potential;GO:0060124//positive regulation of growth hormone secretion;GO:0150099//neuron-glial cell signaling"	--
ENSG00000204687	0	0	0	0	0	0	0	0	0	0	0	0	MAS1L	"MAS1 proto-oncogene like, G protein-coupled receptor [Source:HGNC Symbol;Acc:HGNC:13961]"	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000204688	0	0	0	0	0	0	0	0	0	0	0	0	OR2H1	olfactory receptor family 2 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8252]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204694	0	0	0	0	0	0	0	0	0	0	0	0	OR11A1	olfactory receptor family 11 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8176]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204695	0	0	0	0	0	0	0	0	0	0	0	0	OR14J1	olfactory receptor family 14 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:13971]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204700	0	0	0	0	0	0	0	0	0	0	0	0	OR2J2	olfactory receptor family 2 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:8260]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204701	0	0	0	0	0	0	0	0	0	0	0	0	OR2J3	olfactory receptor family 2 subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:8261]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204702	0	0	0	0	0	0	0	0	0	0	0	0	OR2J1	olfactory receptor family 2 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:8259]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204703	0	0	0	0	0	0	0	0	0	0	0	0	OR2B3	olfactory receptor family 2 subfamily B member 3 [Source:HGNC Symbol;Acc:HGNC:8238]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204704	0	0	0	0	0	0	0	0	0	0	0	0	OR2W1	olfactory receptor family 2 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:8281]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000204710	0	0	0	0	0	0	0	0	0	0	0	0	SPDYC	speedy/RINGO cell cycle regulator family member C [Source:HGNC Symbol;Acc:HGNC:32681]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0007049//cell cycle;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000204711	0	0.228	0	0.174	0.227	0	0	3	0	2	2	0	CFAP95	cilia and flagella associated protein 95 [Source:HGNC Symbol;Acc:HGNC:31422]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000204713	20.176	20.082	21.172	21.681	20.742	21.893	1240	1238	961	987	1077	979	TRIM27	tripartite motif containing 27 [Source:HGNC Symbol;Acc:HGNC:9975]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0016605//PML body;GO:0030904//retromer complex;GO:0031965//nuclear membrane	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000209//protein polyubiquitination;GO:0002820//negative regulation of adaptive immune response;GO:0006469//negative regulation of protein kinase activity;GO:0007283//spermatogenesis;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0016925//protein sumoylation;GO:0032703//negative regulation of interleukin-2 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032880//regulation of protein localization;GO:0032897//negative regulation of viral transcription;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0042147//retrograde transport, endosome to Golgi;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046596//regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051127//positive regulation of actin nucleation;GO:0070534//protein K63-linked ubiquitination;GO:0090281//negative regulation of calcium ion import"	--
ENSG00000204740	0.471	0.37	0.482	0.339	0.237	0.237	18	15	13	10	9	7	MALRD1	MAM and LDL receptor class A domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24331]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0042632//cholesterol homeostasis;GO:0070858//negative regulation of bile acid biosynthetic process	--
ENSG00000204764	1.854	1.379	1.689	1.496	1.41	1.254	163	128	115	98	110	81	RANBP17	RAN binding protein 17 [Source:HGNC Symbol;Acc:HGNC:14428]	Genetic Information Processing	Translation	ko03013//Nucleocytoplasmic transport	K24115	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm	GO:0005049//nuclear export signal receptor activity;GO:0005525//GTP binding;GO:0031267//small GTPase binding	GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0051028//mRNA transport;GO:0051168//nuclear export;GO:0051169//nuclear transport	--
ENSG00000204767	1.518	0.839	0.525	0.752	0.959	1.136	180	100	46	66	96	98	INSYN2B	inhibitory synaptic factor family member 2B [Source:HGNC Symbol;Acc:HGNC:37271]	-	-	-	-	-	-	-	--
ENSG00000204779	0.14	0.077	0.084	0	0.037	0.107	9	5	4	0	2	5	FOXD4L5	forkhead box D4 like 5 [Source:HGNC Symbol;Acc:HGNC:18522]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000204815	1.151	1.517	0.791	0.547	0.498	1.004	52	66	33	21	19	32	ODAD4	outer dynein arm docking complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:25280]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005930//axoneme;GO:0042995//cell projection;GO:0097728//9+0 motile cilium;GO:0097729//9+2 motile cilium;GO:0120228//outer dynein arm docking complex	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0007420//brain development;GO:0007507//heart development;GO:0030324//lung development;GO:0036158//outer dynein arm assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0090660//cerebrospinal fluid circulation;GO:0120197//mucociliary clearance;GO:0120229//protein localization to motile cilium	--
ENSG00000204822	32.301	29.509	35.968	36.349	28.468	33.046	330.68	305.15	273.3	277	247.44	247.37	MRPL53	mitochondrial ribosomal protein L53 [Source:HGNC Symbol;Acc:HGNC:16684]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0005515//protein binding	GO:0032543//mitochondrial translation	--
ENSG00000204839	0.931	0.929	0.692	1.05	0.684	0.863	27	35	22	31	27	16	MROH6	maestro heat like repeat family member 6 [Source:HGNC Symbol;Acc:HGNC:27814]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000204842	16.062	16.667	16.519	17.193	15.54	17.541	1141	1105	864	783	914	874	ATXN2	ataxin 2 [Source:HGNC Symbol;Acc:HGNC:10555]	Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05017//Spinocerebellar ataxia	K23625;K23625;K23625	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005844//polysome;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0002091//negative regulation of receptor internalization;GO:0006417//regulation of translation;GO:0016070//RNA metabolic process;GO:0033962//P-body assembly;GO:0034063//stress granule assembly;GO:0050658//RNA transport	--
ENSG00000204843	58.109	65.61	64.822	68.605	66.064	60.451	5143.7	5643.46	4122.69	4391.72	4828.53	3848.2	DCTN1	dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K04648;K04648;K04648;K04648;K04648	GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005938//cell cortex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0030286//dynein complex;GO:0030424//axon;GO:0030904//retromer complex;GO:0035371//microtubule plus-end;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045171//intercellular bridge;GO:0072686//mitotic spindle;GO:0099738//cell cortex region;GO:0120103//centriolar subdistal appendage	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0015631//tubulin binding;GO:0019901//protein kinase binding;GO:0048156//tau protein binding;GO:0051010//microtubule plus-end binding	"GO:0000132//establishment of mitotic spindle orientation;GO:0000278//mitotic cell cycle;GO:0007049//cell cycle;GO:0007097//nuclear migration;GO:0007399//nervous system development;GO:0007528//neuromuscular junction development;GO:0010457//centriole-centriole cohesion;GO:0021517//ventral spinal cord development;GO:0031116//positive regulation of microtubule polymerization;GO:0031122//cytoplasmic microtubule organization;GO:0034454//microtubule anchoring at centrosome;GO:0042147//retrograde transport, endosome to Golgi;GO:0050905//neuromuscular process;GO:0051081//nuclear membrane disassembly;GO:0051301//cell division;GO:0060236//regulation of mitotic spindle organization;GO:0061744//motor behavior;GO:0070050//neuron cellular homeostasis;GO:0090063//positive regulation of microtubule nucleation;GO:0099558//maintenance of synapse structure;GO:1904398//positive regulation of neuromuscular junction development;GO:1905515//non-motile cilium assembly;GO:1990535//neuron projection maintenance"	--
ENSG00000204849	0.015	0.045	0.035	0	0	0	1.3	4.01	2.28	0	0	0	SPATA31A1	SPATA31 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:23394]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000204851	2.01	2.072	2.024	2.115	2.282	1.828	195	202	145	152	187	129	PNMA8B	PNMA family member 8B [Source:HGNC Symbol;Acc:HGNC:29206]	-	-	-	-	-	-	-	--
ENSG00000204852	66.145	69.881	65.039	53.13	59.232	51.552	2286.72	2447.16	1569.92	1338	1734.07	1264.57	TCTN1	tectonic family member 1 [Source:HGNC Symbol;Acc:HGNC:26113]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection	-	GO:0001701//in utero embryonic development;GO:0001841//neural tube formation;GO:0008589//regulation of smoothened signaling pathway;GO:0021523//somatic motor neuron differentiation;GO:0021537//telencephalon development;GO:0021904//dorsal/ventral neural tube patterning;GO:0021956//central nervous system interneuron axonogenesis;GO:0030030//cell projection organization;GO:0060271//cilium assembly;GO:1904491//protein localization to ciliary transition zone	--
ENSG00000204856	3.25	3.281	2.964	2.888	3.03	3.323	74	74	50	48	58	55	FAM216A	family with sequence similarity 216 member A [Source:HGNC Symbol;Acc:HGNC:30180]	-	-	-	-	-	-	-	--
ENSG00000204859	6.383	6.148	7.389	8.28	7.446	5.223	215	206	153	171	186	155	ZBTB48	zinc finger and BTB domain containing 48 [Source:HGNC Symbol;Acc:HGNC:4930]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005694//chromosome"	GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0010833//telomere maintenance via telomere lengthening;GO:0045893//positive regulation of transcription, DNA-templated"	ZBTB
ENSG00000204866	0	0	0	0	0.064	0	0	0	0	0	1	0	IGFL2	IGF like family member 2 [Source:HGNC Symbol;Acc:HGNC:32929]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000204869	2.085	1.878	1.964	1.785	2.917	1.353	48.66	44.05	33.84	30.86	57.5	22.98	IGFL4	IGF like family member 4 [Source:HGNC Symbol;Acc:HGNC:32931]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding	-	--
ENSG00000204872	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000204873	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-3	keratin associated protein 9-3 [Source:HGNC Symbol;Acc:HGNC:16927]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000204880	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-8	keratin associated protein 4-8 [Source:HGNC Symbol;Acc:HGNC:17230]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0007568//aging;GO:0042633//hair cycle	--
ENSG00000204882	0	0	0	0	0	0	0	0	0	0	0	0	GPR20	G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	--
ENSG00000204887	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP1-4	keratin associated protein 1-4 [Source:HGNC Symbol;Acc:HGNC:18904]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000204889	0	0	0	0	0.097	0	0	0	0	0	3	0	KRT40	keratin 40 [Source:HGNC Symbol;Acc:HGNC:26707]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	GO:0030855//epithelial cell differentiation;GO:0045109//intermediate filament organization	--
ENSG00000204897	0	0	0	0	0	0	0	0	0	0	0	0	KRT25	keratin 25 [Source:HGNC Symbol;Acc:HGNC:30839]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Endocrine system	ko05150//Staphylococcus aureus infection;ko04915//Estrogen signaling pathway	K07604;K07604	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0007010//cytoskeleton organization;GO:0007568//aging;GO:0031069//hair follicle morphogenesis;GO:0042633//hair cycle;GO:0045109//intermediate filament organization	--
ENSG00000204899	3.285	2.924	2.633	3.267	2.66	3.505	152	136	90	112	104	118	MZT1	mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830]	-	-	-	-	GO:0000931//gamma-tubulin large complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031021//interphase microtubule organizing center	GO:0005515//protein binding	GO:0033566//gamma-tubulin complex localization;GO:0051415//microtubule nucleation by interphase microtubule organizing center;GO:0090307//mitotic spindle assembly	--
ENSG00000204909	0	0	0	0	0	0	0	0	0	0	0	0	SPINK9	serine peptidase inhibitor Kazal type 9 [Source:HGNC Symbol;Acc:HGNC:32951]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000204913	0	0	0.145	0.096	0.042	0	0	0	3	2	1	0	LRRC3C	leucine rich repeat containing 3C [Source:HGNC Symbol;Acc:HGNC:40034]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000204918	0	0	0	0	0	0	0	0	0	0	0	0	PRR20B	proline rich 20B [Source:HGNC Symbol;Acc:HGNC:37220]	-	-	-	-	-	-	-	--
ENSG00000204919	0	0	0	0	0	0	0	0	0	0	0	0	PRR20A	proline rich 20A [Source:HGNC Symbol;Acc:HGNC:24754]	-	-	-	-	-	-	-	--
ENSG00000204920	5.036	4.372	4.08	4.257	4.574	3.213	259	237	162	169	201	116	ZNF155	zinc finger protein 155 [Source:HGNC Symbol;Acc:HGNC:12940]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204922	4.366	5.05	5.127	6.6	4.583	4.997	174.49	207.69	155.56	195.4	160.72	147.85	UQCC3	ubiquinol-cytochrome c reductase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:34399]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0070300//phosphatidic acid binding;GO:1901612//cardiolipin binding	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0006754//ATP biosynthetic process;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0042407//cristae formation"	--
ENSG00000204923	0.31	0.323	0.312	0.369	0.357	0.304	36.7	38.43	27.2	32.34	35.61	26.12	FBXO48	F-box protein 48 [Source:HGNC Symbol;Acc:HGNC:33857]	-	-	-	-	GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding	GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000204928	0	0	0	0	0	0	0	0	0	0	0	0	GRXCR2	glutaredoxin and cysteine rich domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33862]	-	-	-	-	GO:0005902//microvillus;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0120043//stereocilium shaft;GO:0120044//stereocilium base	-	GO:0007605//sensory perception of sound;GO:0033365//protein localization to organelle;GO:0060088//auditory receptor cell stereocilium organization;GO:0060122//inner ear receptor cell stereocilium organization	--
ENSG00000204930	0	0	0	0	0.032	0	0	0	0	0	2	0	FAM221B	family with sequence similarity 221 member B [Source:HGNC Symbol;Acc:HGNC:30762]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204936	0	0.022	0	0	0.026	0.044	0	1	0	0	1	1	CD177	CD177 molecule [Source:HGNC Symbol;Acc:HGNC:30072]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030667//secretory granule membrane;GO:0031225//anchored component of membrane;GO:0035579//specific granule membrane;GO:0042995//cell projection;GO:0044853//plasma membrane raft;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0002020//protease binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding	GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0030100//regulation of endocytosis;GO:0032930//positive regulation of superoxide anion generation;GO:0034394//protein localization to cell surface;GO:0043315//positive regulation of neutrophil degranulation;GO:0045087//innate immune response;GO:0045217//cell-cell junction maintenance;GO:0072672//neutrophil extravasation;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:1990266//neutrophil migration;GO:2001044//regulation of integrin-mediated signaling pathway	--
ENSG00000204941	0	0.031	0.04	0.037	0	0	0	1	1	1	0	0	PSG5	pregnancy specific beta-1-glycoprotein 5 [Source:HGNC Symbol;Acc:HGNC:9522]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0007565//female pregnancy	--
ENSG00000204946	3.745	3.762	3.348	3.648	4.183	4.402	320	323	221	239	308	284	ZNF783	zinc finger protein 783 [Source:HGNC Symbol;Acc:HGNC:27222]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000204947	3.271	3.33	2.511	3.134	3.123	3.149	217	222	123	154	175	152	ZNF425	zinc finger protein 425 [Source:HGNC Symbol;Acc:HGNC:20690]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000204950	0.021	0.232	0.029	0.057	0.101	0.029	1	11	1	2	4	1	LRRC10B	leucine rich repeat containing 10B [Source:HGNC Symbol;Acc:HGNC:37215]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204952	0	0	0	0	0	0	0	0	0	0	0	0	FBXO47	F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204954	5.528	5.613	8.603	5.195	5.222	5.832	140	131	130	93	99	95	C12orf73	chromosome 12 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:34450]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0034551//mitochondrial respiratory chain complex III assembly	--
ENSG00000204956	0	0	0.049	0	0	0	0	0	3.6	0	0	0	PCDHGA1	"protocadherin gamma subfamily A, 1 [Source:HGNC Symbol;Acc:HGNC:8696]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000204961	0.021	0.039	0	0.027	0.046	0.01	3	4.34	0	2.21	5	1	PCDHA9	protocadherin alpha 9 [Source:HGNC Symbol;Acc:HGNC:8675]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000204962	0	0.076	0.054	0	0	0.083	0	4.14	4.43	0	0	6.74	PCDHA8	protocadherin alpha 8 [Source:HGNC Symbol;Acc:HGNC:8674]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000204963	0.049	0.02	0	0	0	0.142	3	2.19	0	0	0	11.41	PCDHA7	protocadherin alpha 7 [Source:HGNC Symbol;Acc:HGNC:8673]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0009988//cell-cell recognition	--
ENSG00000204965	0.042	0	0.052	0.056	0.077	0.058	3.63	0	3.4	3.56	5.59	3.68	PCDHA5	protocadherin alpha 5 [Source:HGNC Symbol;Acc:HGNC:8671]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000204967	8.475	8.972	8.189	6.801	8.837	6.953	840.24	857.99	602.94	497.87	709.73	479.7	PCDHA4	protocadherin alpha 4 [Source:HGNC Symbol;Acc:HGNC:8670]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000204969	0.216	0.214	0.163	0.134	0.217	0.279	24.11	23.91	13.45	11.08	10	22.64	PCDHA2	protocadherin alpha 2 [Source:HGNC Symbol;Acc:HGNC:8668]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000204970	0.088	0.07	0.264	0.191	0.251	0.113	5	4	12.58	10.15	12	3.75	PCDHA1	protocadherin alpha 1 [Source:HGNC Symbol;Acc:HGNC:8663]	-	-	-	-	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000204977	11.613	9.413	11.123	8.501	8.344	9.376	746.52	587.41	508.93	412	463	436.09	TRIM13	tripartite motif containing 13 [Source:HGNC Symbol;Acc:HGNC:9976]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0097038//perinuclear endoplasmic reticulum	GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	"GO:0002376//immune system process;GO:0009653//anatomical structure morphogenesis;GO:0010332//response to gamma radiation;GO:0010942//positive regulation of cell death;GO:0016239//positive regulation of macroautophagy;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0032897//negative regulation of viral transcription;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051865//protein autoubiquitination;GO:1904380//endoplasmic reticulum mannose trimming"	--
ENSG00000204978	0	0	0	0	0	0	0	0	0	0	0	0	ERICH4	glutamate rich 4 [Source:HGNC Symbol;Acc:HGNC:34497]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000204979	0	0	0	0	0	0	0	0	0	0	0	0	MS4A13	membrane spanning 4-domains A13 [Source:HGNC Symbol;Acc:HGNC:16674]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000204983	0	0	0	0	0	0	0	0	0	0	0	0	PRSS1	serine protease 1 [Source:HGNC Symbol;Acc:HGNC:9475]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Digestive system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01312;K01312;K01312;K01312	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007586//digestion;GO:0022617//extracellular matrix disassembly	--
ENSG00000204991	0.751	1.083	0.816	1.079	1.065	1.257	44	61	39	53	61	58	SPIRE2	spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0032154//cleavage furrow	GO:0003779//actin binding;GO:0005515//protein binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization;GO:0030041//actin filament polymerization;GO:0036089//cleavage furrow formation;GO:0040038//polar body extrusion after meiotic divisions;GO:0045010//actin nucleation;GO:0046907//intracellular transport;GO:0048193//Golgi vesicle transport;GO:0051295//establishment of meiotic spindle localization;GO:0051639//actin filament network formation;GO:0070649//formin-nucleated actin cable assembly;GO:2000781//positive regulation of double-strand break repair	--
ENSG00000205002	1.641	1.298	2.165	2.017	1.221	2.111	78	62	76	71	49	73	AARD	alanine and arginine rich domain containing protein [Source:HGNC Symbol;Acc:HGNC:33842]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000205022	0	0	0	0	0	0	0	0	0	0	0	0	PABPN1L	"PABPN1 like, cytoplasmic [Source:HGNC Symbol;Acc:HGNC:37237]"	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05164//Influenza A;ko03015//mRNA surveillance pathway	K14396;K14396	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000205029	0	0	0	0	0	0	0	0	0	0	0	0	OR5D16	olfactory receptor family 5 subfamily D member 16 [Source:HGNC Symbol;Acc:HGNC:15283]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205030	0	0	0	0	0	0	0	0	0	0	0	0	OR5L2	olfactory receptor family 5 subfamily L member 2 [Source:HGNC Symbol;Acc:HGNC:8351]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205038	0.324	0.208	0.301	0.13	0.312	0.438	90	52	46	18	53	68	PKHD1L1	PKHD1 like 1 [Source:HGNC Symbol;Acc:HGNC:20313]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032426//stereocilium tip;GO:0120234//stereocilium coat	GO:0038023//signaling receptor activity	GO:0006955//immune response;GO:0007605//sensory perception of sound	--
ENSG00000205045	0	0	0	0	0	0	0	0	0	0	0	0	SLFN12L	schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205060	10.479	11.277	10.199	10.616	12.562	11.1	1427	1445	1019	1054	1148	1074	SLC35B4	solute carrier family 35 member B4 [Source:HGNC Symbol;Acc:HGNC:20584]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005464//UDP-xylose transmembrane transporter activity;GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006111//regulation of gluconeogenesis;GO:0008643//carbohydrate transport;GO:0015790//UDP-xylose transmembrane transport;GO:0055085//transmembrane transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000205076	0	0	0	0	0	0	0	0	0	0	0	0	LGALS7	galectin 7 [Source:HGNC Symbol;Acc:HGNC:6568]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0016936//galactoside binding;GO:0030246//carbohydrate binding	"GO:0006915//apoptotic process;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0010628//positive regulation of gene expression;GO:0032689//negative regulation of interferon-gamma production;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation"	--
ENSG00000205078	0.411	0.771	0.432	0.677	0.324	0.439	9	17	7	11	6	7	SYCE1L	synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236]	-	-	-	-	GO:0000795//synaptonemal complex;GO:0045111//intermediate filament cytoskeleton	-	GO:0007130//synaptonemal complex assembly;GO:0051321//meiotic cell cycle;GO:0070193//synaptonemal complex organization	--
ENSG00000205084	10.331	11.514	11.021	8.429	9.807	8.773	647	730	509	395	503	345	TMEM231	transmembrane protein 231 [Source:HGNC Symbol;Acc:HGNC:37234]	-	-	-	-	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0036038//MKS complex;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0001944//vasculature development;GO:0007224//smoothened signaling pathway;GO:0030030//cell projection organization;GO:0032880//regulation of protein localization;GO:0042733//embryonic digit morphogenesis;GO:0043010//camera-type eye development;GO:0060271//cilium assembly;GO:0060563//neuroepithelial cell differentiation	--
ENSG00000205085	0.153	0.103	0.219	0.211	0.124	0.127	11	11	10	10	8	4	FAM71F2	family with sequence similarity 71 member F2 [Source:HGNC Symbol;Acc:HGNC:27998]	-	-	-	-	GO:0005794//Golgi apparatus	GO:0005515//protein binding	GO:0001675//acrosome assembly	--
ENSG00000205089	0.387	0.459	0.3	0.788	0.673	0.413	21	25	12	32	31	16.4	CCNI2	cyclin I family member 2 [Source:HGNC Symbol;Acc:HGNC:33869]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0044772//mitotic cell cycle phase transition	--
ENSG00000205090	2.772	5.355	6.549	6.223	3.208	3.031	54	89	90	74	45	36	TMEM240	transmembrane protein 240 [Source:HGNC Symbol;Acc:HGNC:25186]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0097060//synaptic membrane	-	-	--
ENSG00000205097	0	0	0	0	0	0	0	0	0	0	0	0	FRG2	FSHD region gene 2 [Source:HGNC Symbol;Acc:HGNC:19136]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000205108	0.011	0.011	0	0	0.027	0	1	1	0	0	2	0	FAM205A	family with sequence similarity 205 member A [Source:HGNC Symbol;Acc:HGNC:41911]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205111	0	0	0	0	0	0	0	0	0	0	0	0	CDKL4	cyclin dependent kinase like 4 [Source:HGNC Symbol;Acc:HGNC:19287]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0051726//regulation of cell cycle	--
ENSG00000205116	0.015	0.03	0	0	0	0.041	1	2	0	0	0	2	TMEM88B	transmembrane protein 88B [Source:HGNC Symbol;Acc:HGNC:37099]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030165//PDZ domain binding	-	--
ENSG00000205126	0	0	0	0	0	0	0	0	0	0	0	0	ACCSL	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like [Source:HGNC Symbol;Acc:HGNC:34391]	-	-	-	-	-	GO:0003824//catalytic activity;GO:0008483//transaminase activity;GO:0030170//pyridoxal phosphate binding	GO:0006520//cellular amino acid metabolic process;GO:0009058//biosynthetic process	--
ENSG00000205129	0.684	0.767	1.434	0.64	0.218	0.182	14	20	19	8	3	3	C4orf47	chromosome 4 open reading frame 47 [Source:HGNC Symbol;Acc:HGNC:34346]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0097731//9+0 non-motile cilium	-	-	--
ENSG00000205133	18.09	12.915	13.452	11.604	9.484	15.445	946	718	525	451	465	505	TRIQK	triple QxxK/R motif containing [Source:HGNC Symbol;Acc:HGNC:27828]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205138	6.9	6.097	6.209	7.116	7.609	7.539	161	143	107	123	150	128	SDHAF1	succinate dehydrogenase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:33867]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0005515//protein binding	GO:0034553//mitochondrial respiratory chain complex II assembly	--
ENSG00000205143	0	0	0	0.035	0.054	0	0	0	0	1	2	0	ARID3C	AT-rich interaction domain 3C [Source:HGNC Symbol;Acc:HGNC:21209]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045121//membrane raft	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	ARID
ENSG00000205155	27.481	31.43	29.006	30.814	28.43	31.384	503	561	400.9	429.55	474.83	429.39	PSENEN	"presenilin enhancer, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:30100]"	Human Diseases;Environmental Information Processing	Neurodegenerative disease;Signal transduction	ko05010//Alzheimer disease;ko04330//Notch signaling pathway	K06170;K06170	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070765//gamma-secretase complex	GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0061133//endopeptidase activator activity	GO:0006509//membrane protein ectodomain proteolysis;GO:0007219//Notch signaling pathway;GO:0007220//Notch receptor processing;GO:0010950//positive regulation of endopeptidase activity;GO:0016485//protein processing;GO:0031293//membrane protein intracellular domain proteolysis;GO:0034205//amyloid-beta formation;GO:0042982//amyloid precursor protein metabolic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity	--
ENSG00000205177	0	0	0	0	0	0	0	0	0	0	0	0	C11orf91	chromosome 11 open reading frame 91 [Source:HGNC Symbol;Acc:HGNC:34444]	-	-	-	-	-	-	-	--
ENSG00000205186	0	0	0	0	0	0	0	0	0	0	0	0	FABP9	fatty acid binding protein 9 [Source:HGNC Symbol;Acc:HGNC:3563]	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko03320//PPAR signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K08753;K08753	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005504//fatty acid binding;GO:0008289//lipid binding	GO:0001675//acrosome assembly;GO:0015908//fatty acid transport	--
ENSG00000205189	6.703	5.729	6.373	5.157	5.646	6.152	968	794	578	515	571	582	ZBTB10	zinc finger and BTB domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30953]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm"	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042162//telomeric DNA binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000205208	3.352	3.277	2.832	3.461	2.272	3.051	234	230	146	179	134	155	C4orf46	chromosome 4 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:27320]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000205209	0.307	1.746	0.232	0.289	0.682	0.225	43	45	24	30	40	23	SCGB2B2	secretoglobin family 2B member 2 [Source:HGNC Symbol;Acc:HGNC:27616]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000205213	14.785	13.495	13.54	12.005	12.25	14.375	1610	1476	1089	967	1127	1139	LGR4	leucine rich repeat containing G protein-coupled receptor 4 [Source:HGNC Symbol;Acc:HGNC:13299]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04309	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0016500//protein-hormone receptor activity	"GO:0001649//osteoblast differentiation;GO:0001818//negative regulation of cytokine production;GO:0001942//hair follicle development;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0009755//hormone-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030154//cell differentiation;GO:0030282//bone mineralization;GO:0030539//male genitalia development;GO:0032922//circadian regulation of gene expression;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0035239//tube morphogenesis;GO:0036335//intestinal stem cell homeostasis;GO:0045087//innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046849//bone remodeling;GO:0048511//rhythmic process;GO:0048565//digestive tract development;GO:0050673//epithelial cell proliferation;GO:0061290//canonical Wnt signaling pathway involved in metanephric kidney development;GO:0072202//cell differentiation involved in metanephros development;GO:0072224//metanephric glomerulus development;GO:0072282//metanephric nephron tubule morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0120163//negative regulation of cold-induced thermogenesis;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis"	--
ENSG00000205220	4.194	4.517	4.744	5.329	5.366	4.273	85	92	71	80	91.87	63	PSMB10	proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K02733	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:1990111//spermatoproteasome complex"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0000902//cell morphogenesis;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006959//humoral immune response;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042098//T cell proliferation;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000205221	0.067	0	0	0	0.043	0	3	0	0	0	2	0	VIT	vitrin [Source:HGNC Symbol;Acc:HGNC:12697]	-	-	-	-	GO:0005576//extracellular region;GO:0005614//interstitial matrix;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005539//glycosaminoglycan binding	GO:0007399//nervous system development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0021510//spinal cord development;GO:0030198//extracellular matrix organization	--
ENSG00000205236	0.754	0.805	0.208	0.34	0.944	0.679	55.82	59.92	11.38	18.65	59.03	36.56	UPK3BL1	"novel protein, UPK3BL-RASA4 readthrough"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205238	0	0	0	0	0.073	0	0	0	0	0	4.09	0	SPDYE2	speedy/RINGO cell cycle regulator family member E2 [Source:HGNC Symbol;Acc:HGNC:33841]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000205250	11.647	10.756	13.303	12.956	13.279	13.912	507	470	430	420	491	443	E2F4	E2F transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3118]	Cellular Processes;Cellular Processes;Environmental Information Processing	Cell growth and death;Cell growth and death;Signal transduction	ko04218//Cellular senescence;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway	K04682;K04682;K04682	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216//DNA-binding transcription activator activity;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding;GO:1990841//promoter-specific chromatin binding"	"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0002064//epithelial cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006884//cell volume homeostasis;GO:0007049//cell cycle;GO:0008015//blood circulation;GO:0008361//regulation of cell size;GO:0009887//animal organ morphogenesis;GO:0030030//cell projection organization;GO:0042127//regulation of cell population proliferation;GO:0044458//motile cilium assembly;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060271//cilium assembly;GO:0098534//centriole assembly;GO:1903251//multi-ciliated epithelial cell differentiation"	E2F
ENSG00000205268	5.216	5.476	3.985	3.153	3.973	3.114	346	348	194	155	223	150	PDE7A	phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791]	Metabolism;Metabolism;Human Diseases	Global and overview maps;Nucleotide metabolism;Substance dependence	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko05032//Morphine addiction	K18436;K18436;K18436	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0019933//cAMP-mediated signaling	--
ENSG00000205269	3.541	2.665	3.304	2.372	2.715	3.108	653	494	450	324	423	417	TMEM170B	transmembrane protein 170B [Source:HGNC Symbol;Acc:HGNC:34244]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0016055//Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000205277	0	0	0	0	0	0	0	0	0	0	0	0	MUC12	"mucin 12, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7510]"	-	-	-	-	GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0001558//regulation of cell growth	--
ENSG00000205279	0	0	0	0	0	0	0	0	0	0	0	0	CTXN3	cortexin 3 [Source:HGNC Symbol;Acc:HGNC:31110]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000205301	0	0	0	0	0	0	0	0	0	0	0	0	MGAT4D	MGAT4 family member D [Source:HGNC Symbol;Acc:HGNC:43619]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K00738;K00738;K00738	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008375//acetylglucosaminyltransferase activity	GO:0006487//protein N-linked glycosylation;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0060051//negative regulation of protein glycosylation	--
ENSG00000205302	23.717	22.458	18.815	19.151	18.962	20.695	1016	944	626	630	622	656	SNX2	sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K17917	"GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030904//retromer complex;GO:0030905//retromer, tubulation complex;GO:0031901//early endosome membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection"	GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity;GO:1990459//transferrin receptor binding;GO:1990460//leptin receptor binding	"GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0034498//early endosome to Golgi transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0072673//lamellipodium morphogenesis"	--
ENSG00000205307	0.342	0.257	0	0.337	0.116	0.134	7	5	0	5	2	2	SAP25	Sin3A associated protein 25 [Source:HGNC Symbol;Acc:HGNC:41908]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000205309	0.868	1.16	1.227	1.182	0.768	1.181	26	35	29	29	18	26	NT5M	"5',3'-nucleotidase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:15769]"	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0008252//nucleotidase activity;GO:0008253//5'-nucleotidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0009117//nucleotide metabolic process;GO:0009223//pyrimidine deoxyribonucleotide catabolic process;GO:0009264//deoxyribonucleotide catabolic process;GO:0016311//dephosphorylation;GO:0046079//dUMP catabolic process	--
ENSG00000205323	27.062	27.501	30.168	23.044	25.5	17.861	505.3	514.88	416.77	321.92	409.92	251.44	SARNP	SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:24432]	-	-	-	-	GO:0000346//transcription export complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0051028//mRNA transport	--
ENSG00000205327	0	0	0	0	0	0	0	0	0	0	0	0	OR6C68	olfactory receptor family 6 subfamily C member 68 [Source:HGNC Symbol;Acc:HGNC:31297]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205328	0	0	0	0	0	0	0	0	0	0	0	0	OR6C65	olfactory receptor family 6 subfamily C member 65 [Source:HGNC Symbol;Acc:HGNC:31295]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205329	0	0	0	0	0	0	0	0	0	0	0	0	OR6C3	olfactory receptor family 6 subfamily C member 3 [Source:HGNC Symbol;Acc:HGNC:15437]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205330	0	0	0	0	0	0	0	0	0	0	0	0	OR6C1	olfactory receptor family 6 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8355]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205336	4.865	9.081	5.39	3.933	3.767	2.752	254	335	160	114	128	115	ADGRG1	adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0070062//extracellular exosome;GO:0097451//glial limiting end-foot	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0050840//extracellular matrix binding	GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007267//cell-cell signaling;GO:0007399//nervous system development;GO:0007420//brain development;GO:0008285//negative regulation of cell population proliferation;GO:0010573//vascular endothelial growth factor production;GO:0016477//cell migration;GO:0021796//cerebral cortex regionalization;GO:0021801//cerebral cortex radial glia-guided migration;GO:0021819//layer formation in cerebral cortex;GO:0030154//cell differentiation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0045785//positive regulation of cell adhesion;GO:0061484//hematopoietic stem cell homeostasis;GO:0070528//protein kinase C signaling;GO:0072520//seminiferous tubule development;GO:2000179//positive regulation of neural precursor cell proliferation;GO:2001223//negative regulation of neuron migration	--
ENSG00000205339	41.24	32.801	33.737	28.988	30.032	32.678	5155	4119	3076	2604	3159	2928	IPO7	importin 7 [Source:HGNC Symbol;Acc:HGNC:9852]	Genetic Information Processing;Environmental Information Processing	Translation;Signal transduction	ko03013//Nucleocytoplasmic transport;ko04013//MAPK signaling pathway - fly	K20223;K20223	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane	GO:0005515//protein binding;GO:0030695//GTPase regulator activity;GO:0031267//small GTPase binding;GO:0042393//histone binding;GO:0046332//SMAD binding	GO:0006606//protein import into nucleus;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0045087//innate immune response;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000205352	39.682	41.946	39.606	44.866	43.687	31.979	828	882	584	686	778	499	PRR13	proline rich 13 [Source:HGNC Symbol;Acc:HGNC:24528]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000205356	5.869	5.909	6.707	7.595	7.216	5.757	636.5	630.34	545.75	522.59	676.59	503.72	TECPR1	tectonin beta-propeller repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:22214]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K17988	GO:0000421//autophagosome membrane;GO:0005654//nucleoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0032991//protein-containing complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0032266//phosphatidylinositol-3-phosphate binding	GO:0006914//autophagy;GO:0016236//macroautophagy;GO:0097352//autophagosome maturation;GO:1901096//regulation of autophagosome maturation	--
ENSG00000205358	0	0.121	0	0	0	0	0	1	0	0	0	0	MT1H	metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000205359	0	0	0	0	0	0	0	0	0	0	0	0	SLCO6A1	solute carrier organic anion transporter family member 6A1 [Source:HGNC Symbol;Acc:HGNC:23613]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity	GO:0006811//ion transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000205362	0	0	0	0	0	0	0	0	0	0	0	0	MT1A	metallothionein 1A [Source:HGNC Symbol;Acc:HGNC:7393]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000205363	0.252	0.288	0.268	0.291	0.971	0.352	33	43	18	32	59	38	INSYN1	inhibitory synaptic factor 1 [Source:HGNC Symbol;Acc:HGNC:33753]	-	-	-	-	GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045202//synapse	GO:0005515//protein binding	GO:0060080//inhibitory postsynaptic potential	--
ENSG00000205364	0	0	0	0.164	0.143	0.666	0	0	0	1	1	4	MT1M	metallothionein 1M [Source:HGNC Symbol;Acc:HGNC:14296]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0045926//negative regulation of growth;GO:0071248//cellular response to metal ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000205403	120.446	122.714	118.453	121.149	120.536	119.993	4879.82	4986	3527	3601	4119.02	3551.56	CFI	complement factor I [Source:HGNC Symbol;Acc:HGNC:5394]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01333;K01333	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response"	--
ENSG00000205409	0	0	0	0	0	0	0	0	0	0	0	0	OR52E6	olfactory receptor family 52 subfamily E member 6 [Source:HGNC Symbol;Acc:HGNC:15215]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205413	0.34	0.251	0.173	0.273	0.25	0.225	48	34	18	27	22	21	SAMD9	sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0034058//endosomal vesicle fusion	--
ENSG00000205420	0	0	0	0	0.025	0	0	0	0	0	1	0	KRT6A	keratin 6A [Source:HGNC Symbol;Acc:HGNC:6443]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0045095//keratin filament;GO:0070062//extracellular exosome	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding	GO:0001899//negative regulation of cytolysis by symbiont of host cells;GO:0002009//morphogenesis of an epithelium;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell population proliferation;GO:0030154//cell differentiation;GO:0042060//wound healing;GO:0050830//defense response to Gram-positive bacterium;GO:0051838//cytolysis by host of symbiont cells;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070268//cornification;GO:2000536//negative regulation of entry of bacterium into host cell	--
ENSG00000205423	7.036	4.034	6.208	5.142	4.762	6.25	300	170	187	166	168	185	CNEP1R1	CTD nuclear envelope phosphatase 1 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:26759]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0071595//Nem1-Spo7 phosphatase complex	GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0034504//protein localization to nucleus;GO:0035307//positive regulation of protein dephosphorylation	--
ENSG00000205426	0.205	0.302	0.068	0.101	0.177	0.24	8.22	12.15	2	3	6	7	KRT81	keratin 81 [Source:HGNC Symbol;Acc:HGNC:6458]	-	-	-	-	GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000205436	0	0	0	0	0	0	0	0	0	0	0	0	EXOC3L4	exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120]	-	-	-	-	GO:0000145//exocyst	GO:0000149//SNARE binding	GO:0006887//exocytosis;GO:0051601//exocyst localization	--
ENSG00000205439	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP12-3	keratin associated protein 12-3 [Source:HGNC Symbol;Acc:HGNC:20531]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000205442	0	0	0	0	0	0	0	0	0	0	0	0	IZUMO3	IZUMO family member 3 [Source:HGNC Symbol;Acc:HGNC:31421]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0042803//protein homodimerization activity	-	--
ENSG00000205445	0.042	0	0	0	0	0	1	0	0	0	0	0	KRTAP10-2	keratin associated protein 10-2 [Source:HGNC Symbol;Acc:HGNC:22967]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000205456	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3D	TP53 target 3D [Source:HGNC Symbol;Acc:HGNC:44657]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000205457	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3C	TP53 target 3C [Source:HGNC Symbol;Acc:HGNC:42962]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000205476	28.301	25.948	34.04	34.491	36.036	32.808	2068.72	2049.39	1721.5	1790.94	2040.62	1822.33	CCDC85C	coiled-coil domain containing 85C [Source:HGNC Symbol;Acc:HGNC:35459]	-	-	-	-	GO:0005912//adherens junction;GO:0005923//bicellular tight junction;GO:0030054//cell junction;GO:0043296//apical junction complex	-	GO:0021987//cerebral cortex development	--
ENSG00000205482	0.56	0.632	0.932	0.887	0.979	1.285	35.71	40.57	43.93	41.93	52.8	59.66	SPDYE18	speedy/RINGO cell cycle regulator family member E18 [Source:HGNC Symbol;Acc:HGNC:51514]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000205495	0	0	0.07	0	0	0	0	0	1	0	0	0	OR52J3	olfactory receptor family 52 subfamily J member 3 [Source:HGNC Symbol;Acc:HGNC:14799]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205496	0	0	0	0	0	0	0	0	0	0	0	0	OR51A2	olfactory receptor family 51 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:14764]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205497	0	0	0	0	0	0	0	0	0	0	0	0	OR51A4	olfactory receptor family 51 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:14795]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000205502	0	0	0	0	0	0	0	0	0	0	0	0	C2CD4B	C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628]	-	-	-	-	GO:0005634//nucleus	-	GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0002675//positive regulation of acute inflammatory response;GO:0030155//regulation of cell adhesion	--
ENSG00000205517	1.053	1.352	1.368	1.123	2.519	1.277	54	67	52	33	66	48	RGL3	ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031267//small GTPase binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0043547//positive regulation of GTPase activity	--
ENSG00000205531	50.642	50.416	49.382	40.149	47.871	44.182	2099	2071	1502	1267	1608	1316	NAP1L4	nucleosome assembly protein 1 like 4 [Source:HGNC Symbol;Acc:HGNC:7640]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0051082//unfolded protein binding	GO:0006334//nucleosome assembly	--
ENSG00000205542	320.992	327.681	265.128	319.725	282.12	273.475	4154	4261	2533	3068	3091	2580	TMSB4X	thymosin beta 4 X-linked [Source:HGNC Symbol;Acc:HGNC:11881]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05764	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031093//platelet alpha granule lumen	GO:0003723//RNA binding;GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005515//protein binding;GO:0019899//enzyme binding	"GO:0007015//actin filament organization;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0030334//regulation of cell migration;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042989//sequestering of actin monomers;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0050727//regulation of inflammatory response;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:1905273//positive regulation of proton-transporting ATP synthase activity, rotational mechanism;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:2001171//positive regulation of ATP biosynthetic process"	--
ENSG00000205544	22.052	20.305	23.125	31.659	17.785	20.924	204	189	158	216.94	139	140.94	TMEM256	transmembrane protein 256 [Source:HGNC Symbol;Acc:HGNC:28618]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000205560	1.012	1.553	2.174	1.367	1.245	2.384	49.47	81.66	68.58	48.42	52.48	90.23	CPT1B	carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329]	Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism;Metabolism	Environmental adaptation;Cardiovascular disease;Endocrine and metabolic disease;Signal transduction;Endocrine and metabolic disease;Endocrine system;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism	ko04714//Thermogenesis;ko05415//Diabetic cardiomyopathy;ko04936//Alcoholic liver disease;ko04152//AMPK signaling pathway;ko04931//Insulin resistance;ko04922//Glucagon signaling pathway;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation	K19523;K19523;K19523;K19523;K19523;K19523;K19523;K19523;K19523;K19523	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004095//carnitine O-palmitoyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016746//acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006853//carnitine shuttle;GO:0009437//carnitine metabolic process;GO:0009637//response to blue light;GO:0015909//long-chain fatty acid transport	--
ENSG00000205571	6.685	6.841	6.138	5.936	8.255	6.385	169.82	158.7	109.26	115.69	150.15	123.54	SMN2	"survival of motor neuron 2, centromeric [Source:HGNC Symbol;Acc:HGNC:11118]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016604//nuclear body;GO:0030018//Z disc;GO:0030424//axon;GO:0032797//SMN complex;GO:0034719//SMN-Sm protein complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0097504//Gemini of coiled bodies	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0006353//DNA-templated transcription, termination;GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing"	--
ENSG00000205572	4.337	5.083	6.298	5.353	5.734	24.687	90.9	119.86	116.04	94.52	106.84	296.15	SERF1B	small EDRK-rich factor 1B [Source:HGNC Symbol;Acc:HGNC:10756]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007399//nervous system development;GO:0031648//protein destabilization;GO:1990000//amyloid fibril formation	--
ENSG00000205581	55.16	55.098	52.432	48.685	47.316	47.112	1445	1454	1012	941	1054	899	HMGN1	high mobility group nucleosome binding domain 1 [Source:HGNC Symbol;Acc:HGNC:4984]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding	"GO:0006325//chromatin organization;GO:0032786//positive regulation of DNA-templated transcription, elongation"	--
ENSG00000205592	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000205593	3.468	3.616	4.407	3.622	3.597	3.707	216	240	165	178	217	177	DENND6B	DENN domain containing 6B [Source:HGNC Symbol;Acc:HGNC:32690]	-	-	-	-	GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0055037//recycling endosome	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000205609	1.017	1.786	0.511	0	2.034	0.723	64.41	113.28	23.91	0	108.82	33.3	EIF3CL	eukaryotic translation initiation factor 3 subunit C like [Source:HGNC Symbol;Acc:HGNC:26347]	-	-	-	-	GO:0005737//cytoplasm;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding	GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006412//translation;GO:0006413//translational initiation	--
ENSG00000205629	23.821	24.592	22.199	23.573	18.201	18.025	653	673	413	475	417	359	LCMT1	leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0003880//protein C-terminal carboxyl O-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0016740//transferase activity;GO:0018423//protein C-terminal leucine carboxyl O-methyltransferase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006464//cellular protein modification process;GO:0006479//protein methylation;GO:0006481//C-terminal protein methylation;GO:0010906//regulation of glucose metabolic process;GO:0031333//negative regulation of protein-containing complex assembly;GO:0032259//methylation;GO:0042981//regulation of apoptotic process;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint	--
ENSG00000205639	0	0.142	0.046	0	0	0	0	3.19	2	0	0	0	MFSD2B	major facilitator superfamily domain containing 2B [Source:HGNC Symbol;Acc:HGNC:37207]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015293//symporter activity;GO:0046624//sphingolipid transporter activity	GO:0006869//lipid transport;GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport;GO:0071702//organic substance transport	--
ENSG00000205642	0.041	0	0	0	0	0	1	0	0	0	0	0	VCX3B	variable charge X-linked 3B [Source:HGNC Symbol;Acc:HGNC:31838]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	-	GO:0007420//brain development	--
ENSG00000205643	3.821	4.192	5.308	3.366	4.274	6.048	118	129	122	77	112	135	CDPF1	cysteine rich DPF motif domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33710]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000205649	0	0	0	0	0	0	0	0	0	0	0	0	HTN3	histatin 3 [Source:HGNC Symbol;Acc:HGNC:5284]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13913	GO:0005576//extracellular region	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0031214//biomineral tissue development;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050832//defense response to fungus	--
ENSG00000205659	3.976	5.24	4.77	5.095	4.646	4.911	237	314	210	225	234	213	LIN52	lin-52 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:19856]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K21775	GO:0070176//DRM complex	-	"GO:0006351//transcription, DNA-templated"	--
ENSG00000205667	0.019	0.077	0	0	0	0	1	4	0	0	0	0	ARSH	arylsulfatase family member H [Source:HGNC Symbol;Acc:HGNC:32488]	-	-	-	-	GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004065//arylsulfatase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000205669	0.048	0	0	0	0.057	0	1	0	0	0	1	0	ACOT6	acyl-CoA thioesterase 6 [Source:HGNC Symbol;Acc:HGNC:33159]	-	-	-	-	GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000205670	0.583	7.791	0.073	2.37	0.155	13.622	18.67	144	2.04	34.9	3.69	174.17	SMIM11	small integral membrane protein 11 [Source:HGNC Symbol;Acc:HGNC:1293]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000205678	0	0	0	0	0	0	0	0	0	0	0	0	TECRL	"trans-2,3-enoyl-CoA reductase like [Source:HGNC Symbol;Acc:HGNC:27365]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors"	GO:0006629//lipid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process	--
ENSG00000205683	0.094	0.121	0.078	0.078	0.128	0.147	8	9	5	5	10	9	DPF3	double PHD fingers 3 [Source:HGNC Symbol;Acc:HGNC:17427]	Organismal Systems;Human Diseases	Environmental adaptation;Cancer: specific types	ko04714//Thermogenesis;ko05225//Hepatocellular carcinoma	K22198;K22198	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016514//SWI/SNF complex;GO:0035060//brahma complex;GO:0071565//nBAF complex	GO:0003712//transcription coregulator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0008150//biological_process;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0045597//positive regulation of cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070316//regulation of G0 to G1 transition;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:2000781//positive regulation of double-strand break repair;GO:2000819//regulation of nucleotide-excision repair"	--
ENSG00000205693	0	0	0.078	0	0	0	0	0	2	0	0	0	MANSC4	MANSC domain containing 4 [Source:HGNC Symbol;Acc:HGNC:40023]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205702	0.058	0	0.094	0	0.034	0.096	2	0	1	0	1	1	CYP2D7	cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:2624]	Organismal Systems;Human Diseases;Metabolism;Metabolism	Nervous system;Drug resistance: antineoplastic;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism	ko04726//Serotonergic synapse;ko01522//Endocrine resistance;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00982//Drug metabolism - cytochrome P450	K17712;K17712;K17712;K17712	-	-	-	--
ENSG00000205704	0.064	0.032	0.086	0.172	0.076	0.044	2	1	2	4	2	1	SMIM45	small integral membrane protein 45 [Source:HGNC Symbol;Acc:HGNC:27930]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205707	14.173	11.83	11.908	11.773	11.453	12.357	347	302	223	218	238.97	225	ETFRF1	electron transfer flavoprotein regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:27052]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0022904//respiratory electron transport chain	--
ENSG00000205710	0	0	0.02	0	0.018	0	0	0	1	0	1	0	C17orf107	chromosome 17 open reading frame 107 [Source:HGNC Symbol;Acc:HGNC:37238]	-	-	-	-	-	-	-	--
ENSG00000205718	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L4	methyl-CpG binding domain protein 3 like 4 [Source:HGNC Symbol;Acc:HGNC:37206]	-	-	-	-	-	-	-	--
ENSG00000205726	10.086	10.215	9.895	8.623	8.495	9.808	1187	1270	809	674	864	757	ITSN1	intersectin 1 [Source:HGNC Symbol;Acc:HGNC:6183]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005905//clathrin-coated pit;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0098793//presynapse	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0060090//molecular adaptor activity;GO:0070064//proline-rich region binding	GO:0006887//exocytosis;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0034613//cellular protein localization;GO:0035556//intracellular signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0150007//clathrin-dependent synaptic vesicle endocytosis	--
ENSG00000205730	7.371	8.128	7.442	4.873	5.65	6.275	1172	1299	874	574	759	726	ITPRIPL2	ITPRIP like 2 [Source:HGNC Symbol;Acc:HGNC:27257]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000205744	2.592	3.226	2.849	3.633	3.153	3.295	151	188	122	156	155	139	DENND1C	DENN domain containing 1C [Source:HGNC Symbol;Acc:HGNC:26225]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:1901981//phosphatidylinositol phosphate binding	GO:0006897//endocytosis;GO:0032456//endocytic recycling;GO:0050790//regulation of catalytic activity	--
ENSG00000205755	0	0	0	0	0	0	0	0	0	0	0	0	CRLF2	cytokine receptor like factor 2 [Source:HGNC Symbol;Acc:HGNC:14281]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05078;K05078	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004896//cytokine receptor activity;GO:0004923//leukemia inhibitory factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005515//protein binding;GO:0019955//cytokine binding	GO:0008284//positive regulation of cell population proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0032754//positive regulation of interleukin-5 production;GO:0033005//positive regulation of mast cell activation;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway;GO:1904894//positive regulation of receptor signaling pathway via STAT	--
ENSG00000205758	7.095	6.601	7.147	5.259	5.609	5.626	222	195	159	128	142	123	CRYZL1	crystallin zeta like 1 [Source:HGNC Symbol;Acc:HGNC:2420]	-	-	-	-	GO:0005829//cytosol	GO:0003960//NADPH:quinone reductase activity;GO:0016491//oxidoreductase activity;GO:0050661//NADP binding	GO:1901661//quinone metabolic process	--
ENSG00000205765	8.023	7.04	7.752	6.514	6.396	8.122	873	770	623	525	588	643	C5orf51	chromosome 5 open reading frame 51 [Source:HGNC Symbol;Acc:HGNC:27750]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0000423//mitophagy	--
ENSG00000205777	0	0	0	0	0	0	0	0	0	0	0	0	GAGE1	G antigen 1 [Source:HGNC Symbol;Acc:HGNC:4098]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000205784	0	0.176	0	0	0	0	0	6	0	0	0	0	ARRDC5	arrestin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:31407]	-	-	-	-	GO:0005737//cytoplasm	GO:0031625//ubiquitin protein ligase binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0015031//protein transport;GO:0016567//protein ubiquitination	--
ENSG00000205795	0.744	0.725	0.707	1.005	0.937	1.001	47	46	33	47	50	46	CYS1	cystin 1 [Source:HGNC Symbol;Acc:HGNC:18525]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	-	--
ENSG00000205808	5.967	6.002	7.375	6.629	7.025	6.28	367	371	335	302	365	281	PLPP6	phospholipid phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:23682]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008195//phosphatidate phosphatase activity;GO:0016787//hydrolase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0052642//lysophosphatidic acid phosphatase activity	GO:0006695//cholesterol biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0018342//protein prenylation;GO:0033383//geranyl diphosphate metabolic process;GO:0045339//farnesyl diphosphate catabolic process;GO:0046839//phospholipid dephosphorylation;GO:1902247//geranylgeranyl diphosphate catabolic process;GO:1902565//positive regulation of neutrophil activation	--
ENSG00000205809	0	0	0	0	0	0	0	0	0	0	0	0	KLRC2	killer cell lectin like receptor C2 [Source:HGNC Symbol;Acc:HGNC:6375]	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation	K24233;K24233	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0023024//MHC class I protein complex binding;GO:0030246//carbohydrate binding;GO:0062081//activating MHC class Ib receptor activity;GO:1990405//protein antigen binding	GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002228//natural killer cell mediated immunity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0032814//regulation of natural killer cell activation;GO:0043323//positive regulation of natural killer cell degranulation;GO:0045087//innate immune response;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000205810	0	0	0	0	0	0	0	0	0	0	0	0	KLRC3	killer cell lectin like receptor C3 [Source:HGNC Symbol;Acc:HGNC:6376]	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation	K24233;K24233	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding	GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006968//cellular defense response;GO:0032814//regulation of natural killer cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity	--
ENSG00000205832	0.192	0.275	0.211	0.389	0.27	0.313	16	23	13	24	19	19	C16orf96	chromosome 16 open reading frame 96 [Source:HGNC Symbol;Acc:HGNC:40031]	-	-	-	-	-	-	-	--
ENSG00000205835	0.252	0.158	0.269	0.465	0.188	0.218	19	12	15	26	12	12	GMNC	geminin coiled-coil domain containing [Source:HGNC Symbol;Acc:HGNC:40049]	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0007049//cell cycle;GO:0008156//negative regulation of DNA replication;GO:0045786//negative regulation of cell cycle;GO:0060271//cilium assembly	--
ENSG00000205838	0.429	0.528	0.402	0.291	0.579	0.53	15	25	21	9	21	19	TTC23L	tetratricopeptide repeat domain 23 like [Source:HGNC Symbol;Acc:HGNC:26355]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0030496//midbody	GO:0005515//protein binding	GO:0034976//response to endoplasmic reticulum stress	--
ENSG00000205846	0	0	0	0	0	0	0	0	0	0	0	0	CLEC6A	C-type lectin domain containing 6A [Source:HGNC Symbol;Acc:HGNC:14556]	Organismal Systems	Immune system	ko04625//C-type lectin receptor signaling pathway	K17514	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0038187//pattern recognition receptor activity;GO:0043274//phospholipase binding;GO:0046872//metal ion binding	GO:0001819//positive regulation of cytokine production;GO:0001878//response to yeast;GO:0001879//detection of yeast;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050832//defense response to fungus;GO:0061760//antifungal innate immune response;GO:1902533//positive regulation of intracellular signal transduction;GO:2000318//positive regulation of T-helper 17 type immune response	--
ENSG00000205856	0	0	0	0	0	0	0	0	0	0	0	0	C22orf42	chromosome 22 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:27160]	-	-	-	-	-	-	-	--
ENSG00000205857	0	0	0	0	0	0	0	0	0	0	0	0	NANOGNB	NANOG neighbor homeobox [Source:HGNC Symbol;Acc:HGNC:24958]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding	-	Homeobox
ENSG00000205858	0	0	0	0	0	0	0	0	0	0	0	0	LRRC72	leucine rich repeat containing 72 [Source:HGNC Symbol;Acc:HGNC:42972]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000205863	0.438	0.594	0.7	0.43	0.282	0.164	11	15	13	8	6	3	C1QTNF9B	C1q and TNF related 9B [Source:HGNC Symbol;Acc:HGNC:34072]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer	GO:0005515//protein binding	-	--
ENSG00000205864	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-6	keratin associated protein 5-6 [Source:HGNC Symbol;Acc:HGNC:23600]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000205867	0.086	0.043	0	0	0.153	0	2	1	0	0	3	0	KRTAP5-2	keratin associated protein 5-2 [Source:HGNC Symbol;Acc:HGNC:23597]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000205869	0	0	0.139	0	0	0	0	0	2	0	0	0	KRTAP5-1	keratin associated protein 5-1 [Source:HGNC Symbol;Acc:HGNC:23596]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000205882	0	0	0	0	0	0	0	0	0	0	0	0	DEFB134	defensin beta 134 [Source:HGNC Symbol;Acc:HGNC:32399]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000205883	0	0	0	0	0	0	0	0	0	0	0	0	DEFB135	defensin beta 135 [Source:HGNC Symbol;Acc:HGNC:32400]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000205884	0	0	0	0	0	0	0	0	0	0	0	0	DEFB136	defensin beta 136 [Source:HGNC Symbol;Acc:HGNC:34433]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium	--
ENSG00000205899	0	0	0	0	0	0.048	0	0	0	0	0	1	BHLHA9	basic helix-loop-helix family member a9 [Source:HGNC Symbol;Acc:HGNC:35126]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0046983//protein dimerization activity"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032502//developmental process	bHLH
ENSG00000205903	4.705	4.854	5.209	5.517	5.665	5.434	632	733	578	614	719	594	ZNF316	zinc finger protein 316 [Source:HGNC Symbol;Acc:HGNC:13843]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000205916	0	0	0	0	0	0	0	0	0	0	0	0	DAZ4	deleted in azoospermia 4 [Source:HGNC Symbol;Acc:HGNC:15966]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000205922	0	0.007	0	0	0	0	0	1	0	0	0	0	ONECUT3	one cut homeobox 3 [Source:HGNC Symbol;Acc:HGNC:13399]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	CUT
ENSG00000205923	0	0	0	0	0	0	0	0	0	0	0	0	CEMP1	cementum protein 1 [Source:HGNC Symbol;Acc:HGNC:32553]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046848//hydroxyapatite binding	GO:0008283//cell population proliferation;GO:0030154//cell differentiation;GO:0031214//biomineral tissue development;GO:0042476//odontogenesis	--
ENSG00000205927	0	0	0	0	0	0	0	0	0	0	0	0	OLIG2	oligodendrocyte transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:9398]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0071837//HMG box domain binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007399//nervous system development;GO:0021522//spinal cord motor neuron differentiation;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0021778//oligodendrocyte cell fate specification;GO:0021794//thalamus development;GO:0030182//neuron differentiation;GO:0042552//myelination;GO:0045665//negative regulation of neuron differentiation;GO:0048663//neuron fate commitment;GO:0048709//oligodendrocyte differentiation;GO:0048714//positive regulation of oligodendrocyte differentiation"	bHLH
ENSG00000205929	0.201	0.384	0.273	0.096	0.252	0.168	17	17	9	6	7	5	C21orf62	chromosome 21 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:1305]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000205937	44.285	45.653	45.28	43.096	46.512	52.942	1566	1664	1236	1202	1434	1411	RNPS1	RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080]	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K14325;K14325	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0035145//exon-exon junction complex;GO:0061574//ASAP complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006351//transcription, DNA-templated;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process;GO:0048025//negative regulation of mRNA splicing, via spliceosome"	--
ENSG00000205944	0	0	0	0	0	0	0	0	0	0	0	0	DAZ2	deleted in azoospermia 2 [Source:HGNC Symbol;Acc:HGNC:15964]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008494//translation activator activity	GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation;GO:0070935//3'-UTR-mediated mRNA stabilization	--
ENSG00000205978	13.879	14.097	14.56	11.926	12.893	11.074	2198	2244	1703	1399	1725	1276	NYNRIN	NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0003729//mRNA binding;GO:0004521//endoribonuclease activity	"GO:0008150//biological_process;GO:0015074//DNA integration;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000205981	11.475	10.5	8.439	9.151	11.202	9.686	309	290	179	188	262	207	DNAJC19	DnaJ heat shock protein family (Hsp40) member C19 [Source:HGNC Symbol;Acc:HGNC:30528]	-	-	-	-	"GO:0001405//PAM complex, Tim23 associated import motor;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex;GO:0098800//inner mitochondrial membrane protein complex;GO:0099617//matrix side of mitochondrial inner membrane"	GO:0001671//ATPase activator activity;GO:0005515//protein binding	GO:0006457//protein folding;GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0007601//visual perception;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0048806//genitalia development;GO:1900208//regulation of cardiolipin metabolic process	--
ENSG00000206013	0	0	0	0	0	0	0	0	0	0	0	0	IFITM5	interferon induced transmembrane protein 5 [Source:HGNC Symbol;Acc:HGNC:16644]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	GO:0001701//in utero embryonic development;GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0060349//bone morphogenesis	--
ENSG00000206026	0	0	0	0	0	0	0	0	0	0	0	0	SMIM21	small integral membrane protein 21 [Source:HGNC Symbol;Acc:HGNC:27598]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000206043	0	0	0	0	0	0	0	0	0	0	0	0	C18orf63	chromosome 18 open reading frame 63 [Source:HGNC Symbol;Acc:HGNC:40037]	-	-	-	-	-	-	-	--
ENSG00000206047	0	0	0	0	0	0	0	0	0	0	0	0	DEFA1	defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0035578//azurophil granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0002227//innate immune response in mucosa;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0010818//T cell chemotaxis;GO:0019731//antibacterial humoral response;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051607//defense response to virus;GO:0051673//membrane disruption in other organism;GO:0051873//killing by host of symbiont cells;GO:0052337//modification by host of symbiont membrane;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000206052	0.874	1.959	0.476	0.622	0.517	1.486	107	126	66	53	82	67	DOK6	docking protein 6 [Source:HGNC Symbol;Acc:HGNC:28301]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding	GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0043410//positive regulation of MAPK cascade	--
ENSG00000206053	38.448	34.891	39.217	33.224	41.533	39.206	2026	2104	1471	1287	1606	1349	JPT2	Jupiter microtubule associated homolog 2 [Source:HGNC Symbol;Acc:HGNC:14137]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	-	-	--
ENSG00000206069	0	0	0	0	0	0	0	0	0	0	0	0	TMEM211	transmembrane protein 211 [Source:HGNC Symbol;Acc:HGNC:33725]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000206072	0	0	0.05	0	0	0	0	0	1	0	0	0	SERPINB11	serpin family B member 11 [Source:HGNC Symbol;Acc:HGNC:14221]	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000206073	0	0	0	0	0	0	0	0	0	0	0	0	SERPINB4	serpin family B member 4 [Source:HGNC Symbol;Acc:HGNC:10570]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis;GO:0042270//protection from natural killer cell mediated cytotoxicity	--
ENSG00000206075	0	0	0	0	0.045	0	0	0	0	0	1	0	SERPINB5	serpin family B member 5 [Source:HGNC Symbol;Acc:HGNC:8949]	Human Diseases;Cellular Processes	Cancer: overview;Cell growth and death	ko05206//MicroRNAs in cancer;ko04115//p53 signaling pathway	K10139;K10139	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding	GO:0002009//morphogenesis of an epithelium;GO:0010951//negative regulation of endopeptidase activity;GO:0030198//extracellular matrix organization;GO:0050678//regulation of epithelial cell proliferation;GO:0060512//prostate gland morphogenesis	--
ENSG00000206077	0.829	0.738	0.981	1.77	1.492	1.514	72	78.87	79	116.42	105.62	141.19	ZDHHC11B	zinc finger DHHC-type containing 11B [Source:HGNC Symbol;Acc:HGNC:32962]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016409//palmitoyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity	GO:0006612//protein targeting to membrane;GO:0018230//peptidyl-L-cysteine S-palmitoylation	--
ENSG00000206102	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-8	keratin associated protein 19-8 [Source:HGNC Symbol;Acc:HGNC:33898]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000206104	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP20-3	keratin associated protein 20-3 [Source:HGNC Symbol;Acc:HGNC:34001]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000206105	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP20-4	keratin associated protein 20-4 [Source:HGNC Symbol;Acc:HGNC:34002]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000206106	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP22-2	keratin associated protein 22-2 [Source:HGNC Symbol;Acc:HGNC:37091]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000206107	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP27-1	keratin associated protein 27-1 [Source:HGNC Symbol;Acc:HGNC:33864]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000206113	0.042	0.063	0.284	0	0	0	2	3	10	0	0	0	CFAP99	cilia and flagella associated protein 99 [Source:HGNC Symbol;Acc:HGNC:51180]	-	-	-	-	-	-	-	--
ENSG00000206127	0.293	0.197	0.154	0.344	0.246	0.245	31.57	21.36	12.25	3.69	22.33	19.19	GOLGA8O	golgin A8 family member O [Source:HGNC Symbol;Acc:HGNC:44406]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000206140	0.571	0.752	0.694	1.071	0.59	0.639	13.95	16.52	12.03	17.8	12.2	10.32	TMEM191C	transmembrane protein 191C [Source:HGNC Symbol;Acc:HGNC:33601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000206150	0	0	0	0	0	0	0	0	0	0	0	0	RNASE13	ribonuclease A family member 13 (inactive) [Source:HGNC Symbol;Acc:HGNC:25285]	-	-	-	-	GO:0005576//extracellular region	GO:0003676//nucleic acid binding	-	--
ENSG00000206172	0	0	0	0	0	0	0	0	0	0	0	0	HBA1	hemoglobin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:4823]	Human Diseases;Human Diseases	Infectious disease: parasitic;Infectious disease: parasitic	ko05143//African trypanosomiasis;ko05144//Malaria	K13822;K13822	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0016020//membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0031838//haptoglobin-hemoglobin complex;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0010942//positive regulation of cell death;GO:0015670//carbon dioxide transport;GO:0015671//oxygen transport;GO:0030185//nitric oxide transport;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000206177	0	0	0	0	0	0	0	0	0	0	0	0	HBM	hemoglobin subunit mu [Source:HGNC Symbol;Acc:HGNC:4826]	-	-	-	-	GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000206181	0.016	0.015	0.021	0	0	0	1	1	1	0	0	0	ELOA2	elongin A2 [Source:HGNC Symbol;Acc:HGNC:30771]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070449//elongin complex	GO:0005515//protein binding	"GO:0006366//transcription by RNA polymerase II;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032784//regulation of DNA-templated transcription, elongation"	--
ENSG00000206190	0.445	0.579	0.346	0.372	0.347	0.099	47	59	27	20	28	8	ATP10A	ATPase phospholipid transporting 10A (putative) [Source:HGNC Symbol;Acc:HGNC:13542]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990531//phospholipid-translocating ATPase complex	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0090554//phosphatidylcholine floppase activity;GO:0140326//ATPase-coupled intramembrane lipid transporter activity;GO:0140345//phosphatidylcholine flippase activity;GO:0140351//glycosylceramide flippase activity	GO:0006869//lipid transport;GO:0008360//regulation of cell shape;GO:0015914//phospholipid transport;GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:1903527//positive regulation of membrane tubulation	--
ENSG00000206199	0.046	0	0.121	0	0.11	0	2	0	4	0	4	0	ANKUB1	ankyrin repeat and ubiquitin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29642]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000206203	0	0	0	0	0	0	0	0	0	0	0	0	TSSK2	testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation	--
ENSG00000206260	0	0	0	0	0	0	0	0	0	0	0	0	PRR23A	proline rich 23A [Source:HGNC Symbol;Acc:HGNC:37172]	-	-	-	-	-	-	-	--
ENSG00000206262	0	0	0	0.016	0	0	0	0	0	1	0	0	FOXL2NB	FOXL2 neighbor [Source:HGNC Symbol;Acc:HGNC:34428]	-	-	-	-	GO:0001650//fibrillar center	-	-	--
ENSG00000206384	0.028	0.117	0	0.262	0.072	0.146	5	16	0	15	11	19	COL6A6	collagen type VI alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:27023]	Environmental Information Processing;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Digestive system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04510//Focal adhesion;ko04974//Protein digestion and absorption;ko04512//ECM-receptor interaction	K06238;K06238;K06238;K06238;K06238	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0030020//extracellular matrix structural constituent conferring tensile strength	GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization	--
ENSG00000206418	16.527	14.119	15.415	15.733	16.16	15.678	736	632	507	519	608	508	RAB12	"RAB12, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:31332]"	-	-	-	-	-	GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0032482//Rab protein signal transduction	--
ENSG00000206422	0	0	0	0	0	0	0	0	0	0	0	0	LRRC30	leucine rich repeat containing 30 [Source:HGNC Symbol;Acc:HGNC:30219]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction	--
ENSG00000206432	0.242	0.186	0.148	0.098	0.146	0.106	53	41	24	16	27	17	TMEM200C	transmembrane protein 200C [Source:HGNC Symbol;Acc:HGNC:37208]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000206474	0	0	0	0	0	0	0	0	0	0	0	0	OR10C1	olfactory receptor family 10 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8165]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000206503	474.65	497.357	558.218	614.824	557.403	556.929	15151.24	15981.25	13164.94	14575.84	15081.64	12935.94	HLA-A	"major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005797//Golgi medial cisterna;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0042612//MHC class I protein complex;GO:0042824//MHC class I peptide loading complex;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0070971//endoplasmic reticulum exit site;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0030881//beta-2-microglobulin binding;GO:0042605//peptide antigen binding;GO:0042608//T cell receptor binding;GO:0042610//CD8 receptor binding;GO:0046977//TAP binding;GO:0062061//TAP complex binding	"GO:0001913//T cell mediated cytotoxicity;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002419//T cell mediated cytotoxicity directed against tumor cell target;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002485//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent;GO:0002486//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0002726//positive regulation of T cell cytokine production;GO:0006955//immune response;GO:0016045//detection of bacterium;GO:0019731//antibacterial humoral response;GO:0019882//antigen processing and presentation;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0032729//positive regulation of interferon-gamma production;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0045087//innate immune response;GO:0045321//leukocyte activation;GO:0050830//defense response to Gram-positive bacterium;GO:0050852//T cell receptor signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:2000566//positive regulation of CD8-positive, alpha-beta T cell proliferation;GO:2000568//positive regulation of memory T cell activation;GO:2001187//positive regulation of CD8-positive, alpha-beta T cell activation"	--
ENSG00000206527	12.401	10.453	9.843	10.603	11.676	9.188	1061	899	622	672	844	572	HACD2	3-hydroxyacyl-CoA dehydratase 2 [Source:HGNC Symbol;Acc:HGNC:9640]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation;ko01040//Biosynthesis of unsaturated fatty acids	K10703;K10703;K10703;K10703	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0016829//lyase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0080023//3R-hydroxyacyl-CoA dehydratase activity;GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0030497//fatty acid elongation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process	--
ENSG00000206530	0.772	0.713	0.857	0.495	0.678	0.472	76.99	82	48.75	39.22	75.02	38.09	CFAP44	cilia and flagella associated protein 44 [Source:HGNC Symbol;Acc:HGNC:25631]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0008233//peptidase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006508//proteolysis;GO:0007288//sperm axoneme assembly;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0060285//cilium-dependent cell motility	--
ENSG00000206531	0	0	0	0	0	0	0	0	0	0	0	0	CD200R1L	CD200 receptor 1 like [Source:HGNC Symbol;Acc:HGNC:24665]	Human Diseases	Infectious disease: viral	ko05167//Kaposi sarcoma-associated herpesvirus infection	K21668	GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0150077//regulation of neuroinflammatory response	--
ENSG00000206535	1.733	1.439	1.751	1.397	1.714	1.742	67	54	50	40	56	49	LNP1	leukemia NUP98 fusion partner 1 [Source:HGNC Symbol;Acc:HGNC:28014]	-	-	-	-	-	-	-	--
ENSG00000206536	0	0	0	0	0	0	0	0	0	0	0	0	OR5K3	olfactory receptor family 5 subfamily K member 3 [Source:HGNC Symbol;Acc:HGNC:31290]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000206538	1.566	1.592	1.362	1.655	1.231	1.124	339	257	141	142	192	177	VGLL3	vestigial like family member 3 [Source:HGNC Symbol;Acc:HGNC:24327]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	--
ENSG00000206549	0.081	0.065	0.132	0.107	0.154	0	5	4	6	4.86	8	0	PRSS50	novel protein identical to PRSS50	-	-	-	-	-	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity	GO:0006508//proteolysis	--
ENSG00000206557	0.033	0.006	0.015	0.037	0.059	0.015	6	1	2	5	9	2	TRIM71	tripartite motif containing 71 [Source:HGNC Symbol;Acc:HGNC:32669]	Human Diseases;Organismal Systems	Cancer: overview;Development and regeneration	ko05206//MicroRNAs in cancer;ko04361//Axon regeneration	K12035;K12035	GO:0000932//P-body;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0030371//translation repressor activity;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0001843//neural tube closure;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010586//miRNA metabolic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0016567//protein ubiquitination;GO:0017148//negative regulation of translation;GO:0021915//neural tube development;GO:0031047//gene silencing by RNA;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051246//regulation of protein metabolic process;GO:0051865//protein autoubiquitination;GO:0060964//regulation of gene silencing by miRNA;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0071310//cellular response to organic substance;GO:0072089//stem cell proliferation;GO:2000177//regulation of neural precursor cell proliferation;GO:2000637//positive regulation of gene silencing by miRNA	--
ENSG00000206559	0.639	0.315	0.157	0.371	0.39	0.42	22.74	22.04	8.05	19.11	14.84	10.83	ZCWPW2	zinc finger CW-type and PWWP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23574]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0046872//metal ion binding	-	--
ENSG00000206560	16.543	13.292	12.601	8.672	10.788	9.931	2148	1715	1166	846	1200	908	ANKRD28	ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0005515//protein binding	-	--
ENSG00000206561	0.72	0.816	0.59	0.726	0.639	0.327	44	49	24	33	33	14	COLQ	collagen like tail subunit of asymmetric acetylcholinesterase [Source:HGNC Symbol;Acc:HGNC:2226]	-	-	-	-	GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0031012//extracellular matrix;GO:0031594//neuromuscular junction;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding	GO:0001507//acetylcholine catabolic process in synaptic cleft;GO:0008582//regulation of synaptic assembly at neuromuscular junction;GO:0030198//extracellular matrix organization;GO:0042135//neurotransmitter catabolic process;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0090150//establishment of protein localization to membrane	--
ENSG00000206562	6.269	4.977	5.867	6.939	4.936	5.929	230	186	150	177	152	181	METTL6	"methyltransferase 6, methylcytidine [Source:HGNC Symbol;Acc:HGNC:28343]"	-	-	-	-	GO:0005575//cellular_component	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0052735//tRNA (cytosine-3-)-methyltransferase activity	GO:0001510//RNA methylation;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000206579	0.104	0.304	0.107	0.105	0.232	0.226	23	37	16	14	40	18	XKR4	XK related 4 [Source:HGNC Symbol;Acc:HGNC:29394]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006915//apoptotic process;GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902742//apoptotic process involved in development	--
ENSG00000211445	119.601	129.146	131.66	131.071	125.545	119.479	3973	4297	3207	3197	3465	2771	GPX3	glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity;GO:0042802//identical protein binding	GO:0006979//response to oxidative stress;GO:0006982//response to lipid hydroperoxide;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000211448	0.337	0.348	0.293	0.415	0.329	0.121	42	21	27	6	21	11	DIO2	iodothyronine deiodinase 2 [Source:HGNC Symbol;Acc:HGNC:2884]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K17904	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004800//thyroxine 5'-deiodinase activity;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity;GO:0031625//ubiquitin protein ligase binding;GO:0033798//thyroxine 5-deiodinase activity	GO:0001514//selenocysteine incorporation;GO:0006590//thyroid hormone generation;GO:0009409//response to cold;GO:0032496//response to lipopolysaccharide;GO:0042403//thyroid hormone metabolic process;GO:0042404//thyroid hormone catabolic process;GO:0042446//hormone biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0050873//brown fat cell differentiation;GO:0120162//positive regulation of cold-induced thermogenesis	--
ENSG00000211450	24.221	26.548	28.651	30.385	24.266	27.803	583	627	479	525	501	483	-	-	-	-	-	-	-	-	-	-
ENSG00000211452	0	0	0	0	0	0	0	0	0	0	0	0	DIO1	iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883]	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K01562	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004800//thyroxine 5'-deiodinase activity;GO:0008430//selenium binding;GO:0016491//oxidoreductase activity	GO:0006520//cellular amino acid metabolic process;GO:0006590//thyroid hormone generation;GO:0042403//thyroid hormone metabolic process;GO:0042446//hormone biosynthetic process	--
ENSG00000211454	0.194	0.073	0.033	0.2	0.204	0	6	3	1	5	5	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211455	24.318	22.663	14.304	8.504	14.172	14.211	2076	1892	1005	609	929	746	STK38L	serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:HGNC:17848]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003779//actin binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0051128//regulation of cellular component organization	--
ENSG00000211456	20.071	18.366	19.77	14.873	15.701	20.648	1464	1258	1044	824	943	1026	SACM1L	SAC1 like phosphatidylinositide phosphatase [Source:HGNC Symbol;Acc:HGNC:17059]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K21797;K21797;K21797	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016311//dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation	--
ENSG00000211460	20.952	21.348	19.949	19.671	19.521	20.064	1348	1321	904	917	1040	923	TSN	translin [Source:HGNC Symbol;Acc:HGNC:12379]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:1902555//endoribonuclease complex	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding	GO:0006310//DNA recombination;GO:0016070//RNA metabolic process;GO:0016246//RNA interference;GO:0030422//production of siRNA involved in RNA interference;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000211584	13.858	11.624	13.721	20.007	18.768	18.017	721	654	559	809	820	731	SLC48A1	solute carrier family 48 member 1 [Source:HGNC Symbol;Acc:HGNC:26035]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0015232//heme transmembrane transporter activity;GO:0020037//heme binding	GO:0015886//heme transport	--
ENSG00000211592	0	0	0	0	37.316	0	0	0	0	0	342	0	IGKC	immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716]	-	-	-	-	-	-	-	--
ENSG00000211593	0	0	0	0	0	0	0	0	0	0	0	0	IGKJ5	immunoglobulin kappa joining 5 [Source:HGNC Symbol;Acc:HGNC:5723]	-	-	-	-	-	-	-	--
ENSG00000211594	0	0	0	0	0	0	0	0	0	0	0	0	IGKJ4	immunoglobulin kappa joining 4 [Source:HGNC Symbol;Acc:HGNC:5722]	-	-	-	-	-	-	-	--
ENSG00000211595	0	0	0	0	0	0	0	0	0	0	0	0	IGKJ3	immunoglobulin kappa joining 3 [Source:HGNC Symbol;Acc:HGNC:5721]	-	-	-	-	-	-	-	--
ENSG00000211596	0	0	0	0	0	0	0	0	0	0	0	0	IGKJ2	immunoglobulin kappa joining 2 [Source:HGNC Symbol;Acc:HGNC:5720]	-	-	-	-	-	-	-	--
ENSG00000211597	0	0	0	0	0	0	0	0	0	0	0	0	IGKJ1	immunoglobulin kappa joining 1 [Source:HGNC Symbol;Acc:HGNC:5719]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211598	0	0	0	0	1.061	0	0	0	0	0	10	0	IGKV4-1	immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211599	0	0	0	0	0	0	0	0	0	0	0	0	IGKV5-2	immunoglobulin kappa variable 5-2 [Source:HGNC Symbol;Acc:HGNC:5835]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211611	0	0	0	0	0	0	0	0	0	0	0	0	IGKV6-21	immunoglobulin kappa variable 6-21 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5836]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211623	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-26	immunoglobulin kappa variable 2D-26 [Source:HGNC Symbol;Acc:HGNC:5798]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211625	0	0	0	0	0.128	0	0	0	0	0	1	0	IGKV3D-20	immunoglobulin kappa variable 3D-20 [Source:HGNC Symbol;Acc:HGNC:5825]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211626	0	0	0	0	0	0	0	0	0	0	0	0	IGKV6D-41	immunoglobulin kappa variable 6D-41 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5838]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211632	0	0	0	0	0	0	0	0	0	0	0	0	IGKV3D-11	immunoglobulin kappa variable 3D-11 [Source:HGNC Symbol;Acc:HGNC:5823]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211633	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-42	immunoglobulin kappa variable 1D-42 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5757]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211637	0	0	0	0	0	0	0	0	0	0	0	0	IGLV4-69	immunoglobulin lambda variable 4-69 [Source:HGNC Symbol;Acc:HGNC:5921]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211638	0	0	0	0	0.276	0	0	0	0	0	2	0	IGLV8-61	immunoglobulin lambda variable 8-61 [Source:HGNC Symbol;Acc:HGNC:5931]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211639	0	0	0	0	0	0	0	0	0	0	0	0	IGLV4-60	immunoglobulin lambda variable 4-60 [Source:HGNC Symbol;Acc:HGNC:5920]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211640	0	0	0	0	0.162	0	0	0	0	0	1	0	IGLV6-57	immunoglobulin lambda variable 6-57 [Source:HGNC Symbol;Acc:HGNC:5927]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211641	0	0	0	0	0	0	0	0	0	0	0	0	IGLV11-55	immunoglobulin lambda variable 11-55 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5886]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211642	0	0	0	0	0	0	0	0	0	0	0	0	IGLV10-54	immunoglobulin lambda variable 10-54 [Source:HGNC Symbol;Acc:HGNC:5884]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211643	0.127	0	0	0	0	0	1	0	0	0	0	0	IGLV5-52	immunoglobulin lambda variable 5-52 [Source:HGNC Symbol;Acc:HGNC:5926]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211644	0	0	0.503	0	0.44	0	0	0	3	0	3	0	IGLV1-51	immunoglobulin lambda variable 1-51 [Source:HGNC Symbol;Acc:HGNC:5882]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211645	0	0	0	0	0	0	0	0	0	0	0	0	IGLV1-50	immunoglobulin lambda variable 1-50 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5881]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211647	0	0	0	0	0	0	0	0	0	0	0	0	IGLV5-48	immunoglobulin lambda variable 5-48 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5925]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211648	0	0	0	0	0	0	0	0	0	0	0	0	IGLV1-47	immunoglobulin lambda variable 1-47 [Source:HGNC Symbol;Acc:HGNC:5880]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211649	0	0	0	0	0.148	0	0	0	0	0	1	0	IGLV7-46	immunoglobulin lambda variable 7-46 [Source:HGNC Symbol;Acc:HGNC:5930]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211650	0	0	0	0	0	0	0	0	0	0	0	0	IGLV5-45	immunoglobulin lambda variable 5-45 [Source:HGNC Symbol;Acc:HGNC:5924]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211651	0	0	0	0	0.244	0	0	0	0	0	2	0	IGLV1-44	immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211652	0	0	0	0	0.148	0	0	0	0	0	1	0	IGLV7-43	immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211653	0	0	0	0	0	0	0	0	0	0	0	0	IGLV1-40	immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211654	0	0	0	0	0	0	0	0	0	0	0	0	IGLV5-37	immunoglobulin lambda variable 5-37 [Source:HGNC Symbol;Acc:HGNC:5922]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211655	0	0	0	0	0	0	0	0	0	0	0	0	IGLV1-36	immunoglobulin lambda variable 1-36 [Source:HGNC Symbol;Acc:HGNC:5876]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211656	0	0	0	0	0	0	0	0	0	0	0	0	IGLV2-33	immunoglobulin lambda variable 2-33 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5892]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211657	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-32	immunoglobulin lambda variable 3-32 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5914]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211658	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-27	immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211659	0	0	0	0	0.3	0	0	0	0	0	2	0	IGLV3-25	immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211660	0	0	0	0	0.227	0	0	0	0	0	2	0	IGLV2-23	immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211661	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-22	immunoglobulin lambda variable 3-22 [Source:HGNC Symbol;Acc:HGNC:5906]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211662	0	0	0	0	0.474	0	0	0	0	0	5	0	IGLV3-21	immunoglobulin lambda variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5905]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211663	0	0	0	0	0.454	0	0	0	0	0	3	0	IGLV3-19	immunoglobulin lambda variable 3-19 [Source:HGNC Symbol;Acc:HGNC:5903]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211664	0	0	0	0	0	0	0	0	0	0	0	0	IGLV2-18	immunoglobulin lambda variable 2-18 [Source:HGNC Symbol;Acc:HGNC:5889]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211665	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-16	immunoglobulin lambda variable 3-16 [Source:HGNC Symbol;Acc:HGNC:5901]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211666	0	0	0	0	0.284	0	0	0	0	0	2	0	IGLV2-14	immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211667	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-12	immunoglobulin lambda variable 3-12 [Source:HGNC Symbol;Acc:HGNC:5898]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211668	0	0	0	0	0.143	0	0	0	0	0	1	0	IGLV2-11	immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211669	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-10	immunoglobulin lambda variable 3-10 [Source:HGNC Symbol;Acc:HGNC:5897]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211670	0	0	0	0	0	0	0	0	0	0	0	0	IGLV3-9	immunoglobulin lambda variable 3-9 [Source:HGNC Symbol;Acc:HGNC:5918]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211672	0	0	0	0	0	0	0	0	0	0	0	0	IGLV4-3	immunoglobulin lambda variable 4-3 [Source:HGNC Symbol;Acc:HGNC:5919]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211673	0	0	0	0	0.143	0	0	0	0	0	1	0	IGLV3-1	immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000211674	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ1	immunoglobulin lambda joining 1 [Source:HGNC Symbol;Acc:HGNC:5863]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211675	0	0	0	0	1.432	0	0	0	0	0	11.54	0	IGLC1	immunoglobulin lambda constant 1 [Source:HGNC Symbol;Acc:HGNC:5855]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	-	-	-	--
ENSG00000211676	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ2	immunoglobulin lambda joining 2 [Source:HGNC Symbol;Acc:HGNC:5864]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	-	-	-	--
ENSG00000211677	0	0	0	0	2.096	0	0	0	0	0	16.97	0	IGLC2	immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0071738//IgD immunoglobulin complex;GO:0071742//IgE immunoglobulin complex;GO:0071745//IgA immunoglobulin complex;GO:0071753//IgM immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211678	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ3	immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	-	-	-	--
ENSG00000211679	0	0	0	0	1.362	0	0	0	0	0	11.03	0	IGLC3	immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0071738//IgD immunoglobulin complex;GO:0071742//IgE immunoglobulin complex;GO:0071745//IgA immunoglobulin complex;GO:0071753//IgM immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211680	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ4	immunoglobulin lambda joining 4 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5866]	-	-	-	-	-	-	-	--
ENSG00000211681	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ5	immunoglobulin lambda joining 5 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5867]	-	-	-	-	-	-	-	--
ENSG00000211682	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ6	immunoglobulin lambda joining 6 [Source:HGNC Symbol;Acc:HGNC:5868]	-	-	-	-	-	-	-	--
ENSG00000211684	0	0	0	0	0	0	0	0	0	0	0	0	IGLJ7	immunoglobulin lambda joining 7 [Source:HGNC Symbol;Acc:HGNC:5869]	-	-	-	-	-	-	-	--
ENSG00000211685	0	0	0	0	0	0	0	0	0	0	0	0	IGLC7	immunoglobulin lambda constant 7 [Source:HGNC Symbol;Acc:HGNC:5861]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	-	-	-	--
ENSG00000211687	0	0	0	0	0	0	0	0	0	0	0	0	TRGJ2	T cell receptor gamma joining 2 [Source:HGNC Symbol;Acc:HGNC:12278]	-	-	-	-	-	-	-	--
ENSG00000211688	0	0	0	0	0	0	0	0	0	0	0	0	TRGJP2	T cell receptor gamma joining P2 [Source:HGNC Symbol;Acc:HGNC:12281]	-	-	-	-	-	-	-	--
ENSG00000211689	0	0	0	0	0	0	0	0	0	0	0	0	TRGC1	T cell receptor gamma constant 1 [Source:HGNC Symbol;Acc:HGNC:12275]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000211690	0	0	0	0	0	0	0	0	0	0	0	0	TRGJ1	T cell receptor gamma joining 1 [Source:HGNC Symbol;Acc:HGNC:12277]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211691	0	0	0	0	0	0	0	0	0	0	0	0	TRGJP	T cell receptor gamma joining P [Source:HGNC Symbol;Acc:HGNC:12279]	-	-	-	-	-	-	-	--
ENSG00000211692	0	0	0	0	0	0	0	0	0	0	0	0	TRGJP1	T cell receptor gamma joining P1 [Source:HGNC Symbol;Acc:HGNC:12280]	-	-	-	-	-	-	-	--
ENSG00000211751	0	0	0	0	0	0	0	0	0	0	0	0	TRBC1	T cell receptor beta constant 1 [Source:HGNC Symbol;Acc:HGNC:12156]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune disease;Infectious disease: bacterial;Signal transduction;Infectious disease: bacterial;Immune disease;Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune disease;Immune system;Immune system;Immune system;Immune disease;Infectious disease: parasitic;Immune disease;Immune system;Cancer: overview;Immune system;Immune disease;Infectious disease: parasitic;Endocrine and metabolic disease;Immune disease	ko04020//Calcium signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04064//NF-kappa B signaling pathway;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05162//Measles;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko05144//Malaria;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000211764	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-1	T cell receptor beta joining 2-1 [Source:HGNC Symbol;Acc:HGNC:12168]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211765	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-2	T cell receptor beta joining 2-2 [Source:HGNC Symbol;Acc:HGNC:12169]	-	-	-	-	-	-	-	--
ENSG00000211766	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-2P	T cell receptor beta joining 2-2P (non-functional) [Source:HGNC Symbol;Acc:HGNC:12170]	-	-	-	-	-	-	-	--
ENSG00000211767	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-3	T cell receptor beta joining 2-3 [Source:HGNC Symbol;Acc:HGNC:12171]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211768	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-4	T cell receptor beta joining 2-4 [Source:HGNC Symbol;Acc:HGNC:12172]	-	-	-	-	-	-	-	--
ENSG00000211769	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-5	T cell receptor beta joining 2-5 [Source:HGNC Symbol;Acc:HGNC:12173]	-	-	-	-	-	-	-	--
ENSG00000211770	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-6	T cell receptor beta joining 2-6 [Source:HGNC Symbol;Acc:HGNC:12174]	-	-	-	-	-	-	-	--
ENSG00000211771	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ2-7	T cell receptor beta joining 2-7 [Source:HGNC Symbol;Acc:HGNC:12175]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211772	0	0	0	0	0.075	0	0	0	0	0	1	0	TRBC2	T cell receptor beta constant 2 [Source:HGNC Symbol;Acc:HGNC:12157]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune disease;Infectious disease: bacterial;Signal transduction;Infectious disease: bacterial;Immune disease;Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune disease;Immune system;Immune system;Immune system;Immune disease;Infectious disease: parasitic;Immune disease;Immune system;Cancer: overview;Immune system;Immune disease;Infectious disease: parasitic;Endocrine and metabolic disease;Immune disease	ko04020//Calcium signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04064//NF-kappa B signaling pathway;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05162//Measles;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko05144//Malaria;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785;K10785	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000211825	0	0	0	0	0	0	0	0	0	0	0	0	TRDJ1	T cell receptor delta joining 1 [Source:HGNC Symbol;Acc:HGNC:12257]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211826	0	0	0	0	0	0	0	0	0	0	0	0	TRDJ4	T cell receptor delta joining 4 [Source:HGNC Symbol;Acc:HGNC:12260]	-	-	-	-	-	-	-	--
ENSG00000211827	0	0	0	0	0	0	0	0	0	0	0	0	TRDJ2	T cell receptor delta joining 2 [Source:HGNC Symbol;Acc:HGNC:12258]	-	-	-	-	-	-	-	--
ENSG00000211828	0	0	0	0	0	0	0	0	0	0	0	0	TRDJ3	T cell receptor delta joining 3 [Source:HGNC Symbol;Acc:HGNC:12259]	-	-	-	-	-	-	-	--
ENSG00000211829	0	0	0	0	0.079	0	0	0	0	0	1	0	TRDC	T cell receptor delta constant [Source:HGNC Symbol;Acc:HGNC:12253]	-	-	-	-	GO:0009897//external side of plasma membrane	-	-	--
ENSG00000211831	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ61	T cell receptor alpha joining 61 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12094]	-	-	-	-	-	-	-	--
ENSG00000211832	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ59	T cell receptor alpha joining 59 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12091]	-	-	-	-	-	-	-	--
ENSG00000211833	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211834	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ57	T cell receptor alpha joining 57 [Source:HGNC Symbol;Acc:HGNC:12089]	-	-	-	-	-	-	-	--
ENSG00000211835	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ56	T cell receptor alpha joining 56 [Source:HGNC Symbol;Acc:HGNC:12088]	-	-	-	-	-	-	-	--
ENSG00000211836	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ54	T cell receptor alpha joining 54 [Source:HGNC Symbol;Acc:HGNC:12086]	-	-	-	-	-	-	-	--
ENSG00000211837	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ53	T cell receptor alpha joining 53 [Source:HGNC Symbol;Acc:HGNC:12085]	-	-	-	-	-	-	-	--
ENSG00000211838	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ52	T cell receptor alpha joining 52 [Source:HGNC Symbol;Acc:HGNC:12084]	-	-	-	-	-	-	-	--
ENSG00000211839	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ50	T cell receptor alpha joining 50 [Source:HGNC Symbol;Acc:HGNC:12082]	-	-	-	-	-	-	-	--
ENSG00000211840	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ49	T cell receptor alpha joining 49 [Source:HGNC Symbol;Acc:HGNC:12080]	-	-	-	-	-	-	-	--
ENSG00000211841	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ48	T cell receptor alpha joining 48 [Source:HGNC Symbol;Acc:HGNC:12079]	-	-	-	-	-	-	-	--
ENSG00000211842	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ47	T cell receptor alpha joining 47 [Source:HGNC Symbol;Acc:HGNC:12078]	-	-	-	-	-	-	-	--
ENSG00000211843	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ46	T cell receptor alpha joining 46 [Source:HGNC Symbol;Acc:HGNC:12077]	-	-	-	-	-	-	-	--
ENSG00000211844	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ45	T cell receptor alpha joining 45 [Source:HGNC Symbol;Acc:HGNC:12076]	-	-	-	-	-	-	-	--
ENSG00000211845	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ44	T cell receptor alpha joining 44 [Source:HGNC Symbol;Acc:HGNC:12075]	-	-	-	-	-	-	-	--
ENSG00000211846	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ43	T cell receptor alpha joining 43 [Source:HGNC Symbol;Acc:HGNC:12074]	-	-	-	-	-	-	-	--
ENSG00000211847	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ42	T cell receptor alpha joining 42 [Source:HGNC Symbol;Acc:HGNC:12073]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211848	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ41	T cell receptor alpha joining 41 [Source:HGNC Symbol;Acc:HGNC:12072]	-	-	-	-	-	-	-	--
ENSG00000211849	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ40	T cell receptor alpha joining 40 [Source:HGNC Symbol;Acc:HGNC:12071]	-	-	-	-	-	-	-	--
ENSG00000211850	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ39	T cell receptor alpha joining 39 [Source:HGNC Symbol;Acc:HGNC:12069]	-	-	-	-	-	-	-	--
ENSG00000211851	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ38	T cell receptor alpha joining 38 [Source:HGNC Symbol;Acc:HGNC:12068]	-	-	-	-	-	-	-	--
ENSG00000211854	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ35	T cell receptor alpha joining 35 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12065]	-	-	-	-	-	-	-	--
ENSG00000211855	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ34	T cell receptor alpha joining 34 [Source:HGNC Symbol;Acc:HGNC:12064]	-	-	-	-	-	-	-	--
ENSG00000211856	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ33	T cell receptor alpha joining 33 [Source:HGNC Symbol;Acc:HGNC:12063]	-	-	-	-	-	-	-	--
ENSG00000211857	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ32	T cell receptor alpha joining 32 [Source:HGNC Symbol;Acc:HGNC:12062]	-	-	-	-	-	-	-	--
ENSG00000211858	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ31	T cell receptor alpha joining 31 [Source:HGNC Symbol;Acc:HGNC:12061]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211859	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ30	T cell receptor alpha joining 30 [Source:HGNC Symbol;Acc:HGNC:12060]	-	-	-	-	-	-	-	--
ENSG00000211860	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ29	T cell receptor alpha joining 29 [Source:HGNC Symbol;Acc:HGNC:12058]	-	-	-	-	-	-	-	--
ENSG00000211861	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ28	T cell receptor alpha joining 28 [Source:HGNC Symbol;Acc:HGNC:12057]	-	-	-	-	-	-	-	--
ENSG00000211862	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ27	T cell receptor alpha joining 27 [Source:HGNC Symbol;Acc:HGNC:12056]	-	-	-	-	-	-	-	--
ENSG00000211863	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ26	T cell receptor alpha joining 26 [Source:HGNC Symbol;Acc:HGNC:12055]	-	-	-	-	-	-	-	--
ENSG00000211864	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ25	T cell receptor alpha joining 25 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12054]	-	-	-	-	-	-	-	--
ENSG00000211865	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ24	T cell receptor alpha joining 24 [Source:HGNC Symbol;Acc:HGNC:12053]	-	-	-	-	-	-	-	--
ENSG00000211866	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ23	T cell receptor alpha joining 23 [Source:HGNC Symbol;Acc:HGNC:12052]	-	-	-	-	-	-	-	--
ENSG00000211867	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ22	T cell receptor alpha joining 22 [Source:HGNC Symbol;Acc:HGNC:12051]	-	-	-	-	-	-	-	--
ENSG00000211868	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ21	T cell receptor alpha joining 21 [Source:HGNC Symbol;Acc:HGNC:12050]	-	-	-	-	-	-	-	--
ENSG00000211869	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ20	T cell receptor alpha joining 20 [Source:HGNC Symbol;Acc:HGNC:12049]	-	-	-	-	-	-	-	--
ENSG00000211870	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ19	T cell receptor alpha joining 19 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12047]	-	-	-	-	-	-	-	--
ENSG00000211871	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ18	T cell receptor alpha joining 18 [Source:HGNC Symbol;Acc:HGNC:12046]	-	-	-	-	-	-	-	--
ENSG00000211872	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ17	T cell receptor alpha joining 17 [Source:HGNC Symbol;Acc:HGNC:12045]	-	-	-	-	-	-	-	--
ENSG00000211873	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ16	T cell receptor alpha joining 16 [Source:HGNC Symbol;Acc:HGNC:12044]	-	-	-	-	-	-	-	--
ENSG00000211875	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ14	T cell receptor alpha joining 14 [Source:HGNC Symbol;Acc:HGNC:12042]	-	-	-	-	-	-	-	--
ENSG00000211876	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ13	T cell receptor alpha joining 13 [Source:HGNC Symbol;Acc:HGNC:12041]	-	-	-	-	-	-	-	--
ENSG00000211877	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ12	T cell receptor alpha joining 12 [Source:HGNC Symbol;Acc:HGNC:12040]	-	-	-	-	-	-	-	--
ENSG00000211878	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ11	T cell receptor alpha joining 11 [Source:HGNC Symbol;Acc:HGNC:12039]	-	-	-	-	-	-	-	--
ENSG00000211879	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ10	T cell receptor alpha joining 10 [Source:HGNC Symbol;Acc:HGNC:12038]	-	-	-	-	-	-	-	--
ENSG00000211880	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ9	T cell receptor alpha joining 9 [Source:HGNC Symbol;Acc:HGNC:12097]	-	-	-	-	-	-	-	--
ENSG00000211882	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ7	T cell receptor alpha joining 7 [Source:HGNC Symbol;Acc:HGNC:12095]	-	-	-	-	-	-	-	--
ENSG00000211883	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ6	T cell receptor alpha joining 6 [Source:HGNC Symbol;Acc:HGNC:12092]	-	-	-	-	-	-	-	--
ENSG00000211884	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ5	T cell receptor alpha joining 5 [Source:HGNC Symbol;Acc:HGNC:12081]	-	-	-	-	-	-	-	--
ENSG00000211885	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ4	T cell receptor alpha joining 4 [Source:HGNC Symbol;Acc:HGNC:12070]	-	-	-	-	-	-	-	--
ENSG00000211886	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ3	T cell receptor alpha joining 3 [Source:HGNC Symbol;Acc:HGNC:12059]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211887	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ2	T cell receptor alpha joining 2 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12048]	-	-	-	-	-	-	-	--
ENSG00000211888	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ1	T cell receptor alpha joining 1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:12037]	-	-	-	-	-	-	-	--
ENSG00000211890	0	0	0	0	0.226	0	0	0	0	0	5	0	IGHA2	immunoglobulin heavy constant alpha 2 (A2m marker) [Source:HGNC Symbol;Acc:HGNC:5479]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071745//IgA immunoglobulin complex;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071751//secretory IgA immunoglobulin complex;GO:0071752//secretory dimeric IgA immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0003094//glomerular filtration;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation;GO:0060267//positive regulation of respiratory burst"	--
ENSG00000211891	0	0	0	0	0	0	0	0	0	0	0	0	IGHE	immunoglobulin heavy constant epsilon [Source:HGNC Symbol;Acc:HGNC:5522]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0071742//IgE immunoglobulin complex"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211892	0	0	0	0	0.207	0	0	0	0	0	4.05	0	IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker) [Source:HGNC Symbol;Acc:HGNC:5528]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211893	0	0	0	0	2.942	0	0	0	0	0	57.53	0	IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211895	0	0	0	0	1.18	0	0	0	0	0	23	0	IGHA1	immunoglobulin heavy constant alpha 1 [Source:HGNC Symbol;Acc:HGNC:5478]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0071745//IgA immunoglobulin complex;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071751//secretory IgA immunoglobulin complex;GO:0071752//secretory dimeric IgA immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0003094//glomerular filtration;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0018298//protein-chromophore linkage;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation;GO:0060267//positive regulation of respiratory burst"	--
ENSG00000211896	0	0	0	0	16.766	0	0	0	0	0	331.42	0	IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071735//IgG immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0034987//immunoglobulin receptor binding;GO:0034988//Fc-gamma receptor I complex binding	"GO:0001788//antibody-dependent cellular cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation;GO:0097278//complement-dependent cytotoxicity"	--
ENSG00000211897	0	0	0	0	0.135	0	0	0	0	0	3	0	IGHG3	immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000211898	0	0	0	0	0	0	0	0	0	0	0	0	IGHD	immunoglobulin heavy constant delta [Source:HGNC Symbol;Acc:HGNC:5480]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000211899	0	0	0	0	0.961	0	0	0	0	0	25	0	IGHM	immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0071753//IgM immunoglobulin complex;GO:0071756//pentameric IgM immunoglobulin complex;GO:0071757//hexameric IgM immunoglobulin complex;GO:0072562//blood microparticle"	GO:0003697//single-stranded DNA binding;GO:0003823//antigen binding;GO:0031210//phosphatidylcholine binding;GO:0034987//immunoglobulin receptor binding;GO:0042834//peptidoglycan binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211900	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ6	immunoglobulin heavy joining 6 [Source:HGNC Symbol;Acc:HGNC:5540]	-	-	-	-	-	-	-	--
ENSG00000211904	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ2	immunoglobulin heavy joining 2 [Source:HGNC Symbol;Acc:HGNC:5534]	-	-	-	-	-	-	-	--
ENSG00000211905	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ1	immunoglobulin heavy joining 1 [Source:HGNC Symbol;Acc:HGNC:5532]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000211907	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1-26	immunoglobulin heavy diversity 1-26 [Source:HGNC Symbol;Acc:HGNC:5485]	-	-	-	-	-	-	-	--
ENSG00000211909	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5-24	immunoglobulin heavy diversity 5-24 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5510]	-	-	-	-	-	-	-	--
ENSG00000211911	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211912	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211914	0	0	0	0	0	0	0	0	0	0	0	0	IGHD6-19	immunoglobulin heavy diversity 6-19 [Source:HGNC Symbol;Acc:HGNC:5515]	-	-	-	-	-	-	-	--
ENSG00000211915	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5-18	immunoglobulin heavy diversity 5-18 [Source:HGNC Symbol;Acc:HGNC:5509]	-	-	-	-	-	-	-	--
ENSG00000211917	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211918	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211920	0	0	0	0	0	0	0	0	0	0	0	0	IGHD6-13	immunoglobulin heavy diversity 6-13 [Source:HGNC Symbol;Acc:HGNC:5514]	-	-	-	-	-	-	-	--
ENSG00000211921	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5-12	immunoglobulin heavy diversity 5-12 [Source:HGNC Symbol;Acc:HGNC:5508]	-	-	-	-	-	-	-	--
ENSG00000211923	0	0	0	0	0	0	0	0	0	0	0	0	IGHD3-10	immunoglobulin heavy diversity 3-10 [Source:HGNC Symbol;Acc:HGNC:5495]	-	-	-	-	-	-	-	--
ENSG00000211924	0	0	0	0	0	0	0	0	0	0	0	0	IGHD3-9	immunoglobulin heavy diversity 3-9 [Source:HGNC Symbol;Acc:HGNC:5499]	-	-	-	-	-	-	-	--
ENSG00000211925	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211928	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5-5	immunoglobulin heavy diversity 5-5 [Source:HGNC Symbol;Acc:HGNC:5511]	-	-	-	-	-	-	-	--
ENSG00000211930	0	0	0	0	0	0	0	0	0	0	0	0	IGHD3-3	immunoglobulin heavy diversity 3-3 [Source:HGNC Symbol;Acc:HGNC:5498]	-	-	-	-	-	-	-	--
ENSG00000211931	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000211933	0	0	0	0	0.138	0	0	0	0	0	1	0	IGHV6-1	immunoglobulin heavy variable 6-1 [Source:HGNC Symbol;Acc:HGNC:5662]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211934	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-2	immunoglobulin heavy variable 1-2 [Source:HGNC Symbol;Acc:HGNC:5550]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211935	0	0	0	0	0.289	0	0	0	0	0	2	0	IGHV1-3	immunoglobulin heavy variable 1-3 [Source:HGNC Symbol;Acc:HGNC:5552]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211937	0	0	0	0	0	0	0	0	0	0	0	0	IGHV2-5	immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211938	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-7	immunoglobulin heavy variable 3-7 [Source:HGNC Symbol;Acc:HGNC:5620]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211941	0	0	0	0	0.241	0	0	0	0	0	2	0	IGHV3-11	immunoglobulin heavy variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5580]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211942	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-13	immunoglobulin heavy variable 3-13 [Source:HGNC Symbol;Acc:HGNC:5581]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211943	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-15	immunoglobulin heavy variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5582]	-	-	-	-	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211944	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-16	immunoglobulin heavy variable 3-16 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5583]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211945	0	0	0	0	0.139	0	0	0	0	0	1	0	IGHV1-18	immunoglobulin heavy variable 1-18 [Source:HGNC Symbol;Acc:HGNC:5549]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211946	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-20	immunoglobulin heavy variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5585]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211947	0	0	0	0	0.265	0	0	0	0	0	2	0	IGHV3-21	immunoglobulin heavy variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5586]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211949	0	0	0	0	0.396	0	0	0	0	0	3	0	IGHV3-23	immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome;GO:0072562//blood microparticle"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211950	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-24	immunoglobulin heavy variable 1-24 [Source:HGNC Symbol;Acc:HGNC:5551]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211951	0	0	0	0	0	0	0	0	0	0	0	0	IGHV2-26	immunoglobulin heavy variable 2-26 [Source:HGNC Symbol;Acc:HGNC:5575]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211952	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4-28	immunoglobulin heavy variable 4-28 [Source:HGNC Symbol;Acc:HGNC:5645]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211955	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-33	immunoglobulin heavy variable 3-33 [Source:HGNC Symbol;Acc:HGNC:5596]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211956	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4-34	immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211957	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-35	immunoglobulin heavy variable 3-35 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5598]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211958	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-38	immunoglobulin heavy variable 3-38 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5601]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211959	0	0	0	0	0.134	0	0	0	0	0	1	0	IGHV4-39	immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211961	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-45	immunoglobulin heavy variable 1-45 [Source:HGNC Symbol;Acc:HGNC:5553]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211962	0	0	0	0	0.087	0	0	0	0	0	1	0	IGHV1-46	immunoglobulin heavy variable 1-46 [Source:HGNC Symbol;Acc:HGNC:5554]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211964	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-48	immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211965	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-49	immunoglobulin heavy variable 3-49 [Source:HGNC Symbol;Acc:HGNC:5607]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211966	0	0	0	0	0.418	0	0	0	0	0	3	0	IGHV5-51	immunoglobulin heavy variable 5-51 [Source:HGNC Symbol;Acc:HGNC:5659]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211967	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-53	immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211968	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-58	immunoglobulin heavy variable 1-58 [Source:HGNC Symbol;Acc:HGNC:5555]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211970	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4-61	immunoglobulin heavy variable 4-61 [Source:HGNC Symbol;Acc:HGNC:5655]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211972	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-66	immunoglobulin heavy variable 3-66 [Source:HGNC Symbol;Acc:HGNC:5619]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211973	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-69	immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211974	0	0	0	0	0	0	0	0	0	0	0	0	IGHV2-70D	immunoglobulin heavy variable 2-70D [Source:HGNC Symbol;Acc:HGNC:49602]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211976	0	0	0	0	0.131	0	0	0	0	0	1	0	IGHV3-73	immunoglobulin heavy variable 3-73 [Source:HGNC Symbol;Acc:HGNC:5623]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000211979	0	0	0	0	0	0	0	0	0	0	0	0	IGHV7-81	immunoglobulin heavy variable 7-81 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5669]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000212122	0.059	0.039	0.107	0	0.094	0.027	3	2	4	0	4	1	TSSK1B	testis specific serine kinase 1B [Source:HGNC Symbol;Acc:HGNC:14968]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031410//cytoplasmic vesicle;GO:0031514//motile cilium;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0035556//intracellular signal transduction	--
ENSG00000212123	0.492	0.314	0.358	0.2	0.278	0.241	14	9	9	5	8	5	PRR22	proline rich 22 [Source:HGNC Symbol;Acc:HGNC:28354]	-	-	-	-	-	-	-	--
ENSG00000212124	0.048	0	0	0	0	0.066	1	0	0	0	0	1	TAS2R19	taste 2 receptor member 19 [Source:HGNC Symbol;Acc:HGNC:19108]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000212126	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R50	taste 2 receptor member 50 [Source:HGNC Symbol;Acc:HGNC:18882]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000212127	0.156	0.285	0.141	0.07	0.123	0.357	6	11	4	2	4	10	TAS2R14	taste 2 receptor member 14 [Source:HGNC Symbol;Acc:HGNC:14920]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000212128	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R13	taste 2 receptor member 13 [Source:HGNC Symbol;Acc:HGNC:14919]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000212657	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP16-1	keratin associated protein 16-1 [Source:HGNC Symbol;Acc:HGNC:18916]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000212658	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP29-1	keratin associated like protein 29-1 [Source:HGNC Symbol;Acc:HGNC:34211]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000212659	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-6	keratin associated protein 9-6 [Source:HGNC Symbol;Acc:HGNC:18914]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000212710	0.056	0.056	0	0	0.013	0.046	5	5	0	0	1	3	CTAGE1	cutaneous T cell lymphoma-associated antigen 1 [Source:HGNC Symbol;Acc:HGNC:24346]	-	-	-	-	GO:0005575//cellular_component;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0008150//biological_process;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000212721	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-11	keratin associated protein 4-11 [Source:HGNC Symbol;Acc:HGNC:18911]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000212722	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-9	keratin associated protein 4-9 [Source:HGNC Symbol;Acc:HGNC:18910]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0007568//aging;GO:0042633//hair cycle	--
ENSG00000212724	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP2-3	keratin associated protein 2-3 [Source:HGNC Symbol;Acc:HGNC:18906]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000212725	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP2-1	keratin associated protein 2-1 [Source:HGNC Symbol;Acc:HGNC:16775]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000212747	8.55	9.829	8.854	9.875	9.698	9.433	360	416	275.34	308	345	289	RTL8B	retrotransposon Gag like 8B [Source:HGNC Symbol;Acc:HGNC:33156]	-	-	-	-	GO:0005730//nucleolus	GO:0005515//protein binding	-	--
ENSG00000212807	0.104	0.101	0.016	0.13	0.058	0	10.64	10.39	1.24	9.9	5	0	OR2A42	olfactory receptor family 2 subfamily A member 42 [Source:HGNC Symbol;Acc:HGNC:31230]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000212864	9.854	10.633	12.2	12.763	10.965	12.099	248	261	220	232	246	213	RNF208	ring finger protein 208 [Source:HGNC Symbol;Acc:HGNC:25420]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination	--
ENSG00000212899	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP3-3	keratin associated protein 3-3 [Source:HGNC Symbol;Acc:HGNC:18890]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	-	--
ENSG00000212900	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP3-2	keratin associated protein 3-2 [Source:HGNC Symbol;Acc:HGNC:16779]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	-	--
ENSG00000212901	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP3-1	keratin associated protein 3-1 [Source:HGNC Symbol;Acc:HGNC:16778]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	-	--
ENSG00000212907	1479.294	1546.986	1631.051	2256.759	1659.106	1713.626	9113	9579	7421	10298	8635	7681	MT-ND4L	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L [Source:HGNC Symbol;Acc:HGNC:7460]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03882;K03882;K03882;K03882;K03882;K03882;K03882;K03882;K03882;K03882;K03882;K03882	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome;GO:0110165//cellular anatomical entity	"GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0042773//ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000212916	0.748	0.574	0.593	0.663	0.405	0.851	70	54	41	46	32	58	MAP10	microtubule associated protein 10 [Source:HGNC Symbol;Acc:HGNC:29265]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0030496//midbody;GO:0097431//mitotic spindle pole;GO:1990023//mitotic spindle midzone	GO:0008017//microtubule binding	GO:0000226//microtubule cytoskeleton organization;GO:0007049//cell cycle;GO:0031122//cytoplasmic microtubule organization;GO:0032467//positive regulation of cytokinesis;GO:0032886//regulation of microtubule-based process;GO:0051256//mitotic spindle midzone assembly;GO:0051301//cell division	--
ENSG00000212933	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP12-4	keratin associated protein 12-4 [Source:HGNC Symbol;Acc:HGNC:20532]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000212935	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-3	keratin associated protein 10-3 [Source:HGNC Symbol;Acc:HGNC:22968]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000212938	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP6-3	keratin associated protein 6-3 [Source:HGNC Symbol;Acc:HGNC:18933]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	GO:0031424//keratinization	--
ENSG00000212993	1.053	0.571	0.771	0.98	0.845	1.123	33	30	20	36	26	34	POU5F1B	POU class 5 homeobox 1B [Source:HGNC Symbol;Acc:HGNC:9223]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K09367	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Pou
ENSG00000213015	23.158	26.478	31.099	31.539	31.492	34.812	541.94	629	523	565	647	591	ZNF580	zinc finger protein 580 [Source:HGNC Symbol;Acc:HGNC:29473]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001938//positive regulation of endothelial cell proliferation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0010595//positive regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0032757//positive regulation of interleukin-8 production;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070301//cellular response to hydrogen peroxide	zf-C2H2
ENSG00000213020	1.841	1.034	1.325	0.927	0.825	0.479	91	68	35	33.4	59	28	ZNF611	zinc finger protein 611 [Source:HGNC Symbol;Acc:HGNC:28766]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213022	0	0	0	0	0	0	0	0	0	0	0	0	KLK9	kallikrein related peptidase 9 [Source:HGNC Symbol;Acc:HGNC:6370]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000213023	3.185	3.215	3.665	3.555	2.923	3.285	170	174	146	141	132	131	SYT3	synaptotagmin 3 [Source:HGNC Symbol;Acc:HGNC:11511]	-	-	-	-	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0070382//exocytic vesicle	GO:0000149//SNARE binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0030276//clathrin binding;GO:0046872//metal ion binding	GO:0014059//regulation of dopamine secretion;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0030154//cell differentiation;GO:0071277//cellular response to calcium ion;GO:1903861//positive regulation of dendrite extension	--
ENSG00000213024	17.794	17.697	20.043	19.042	19.308	17.84	1122.23	1089	845.03	834.09	999.15	768	NUP62	nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14306;K14306	GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0031965//nuclear membrane;GO:0044613//nuclear pore central transport channel;GO:0072686//mitotic spindle;GO:0090543//Flemming body;GO:1990904//ribonucleoprotein complex	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0017056//structural constituent of nuclear pore;GO:0030159//signaling receptor complex adaptor activity;GO:0030544//Hsp70 protein binding;GO:0042169//SH2 domain binding;GO:0043130//ubiquitin binding;GO:0051425//PTB domain binding;GO:0051879//Hsp90 protein binding	"GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0006913//nucleocytoplasmic transport;GO:0007080//mitotic metaphase plate congression;GO:0007098//centrosome cycle;GO:0007100//mitotic centrosome separation;GO:0007166//cell surface receptor signaling pathway;GO:0007569//cell aging;GO:0008219//cell death;GO:0008285//negative regulation of cell population proliferation;GO:0009966//regulation of signal transduction;GO:0015031//protein transport;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043407//negative regulation of MAP kinase activity;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0045840//positive regulation of mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046578//regulation of Ras protein signal transduction;GO:0046580//negative regulation of Ras protein signal transduction;GO:0046601//positive regulation of centriole replication;GO:0051028//mRNA transport;GO:0051169//nuclear transport;GO:0060236//regulation of mitotic spindle organization;GO:0098534//centriole assembly;GO:1903438//positive regulation of mitotic cytokinetic process;GO:1904781//positive regulation of protein localization to centrosome"	--
ENSG00000213030	0	0.249	0	0	0	0	0	4.61	0	0	0	0	CGB8	chorionic gonadotropin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:16453]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0061696//pituitary gonadotropin complex	GO:0005102//signaling receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0009755//hormone-mediated signaling pathway	--
ENSG00000213047	2.182	1.634	1.262	1.523	1.057	1.473	328	217	139	123	137	142	DENND1B	DENN domain containing 1B [Source:HGNC Symbol;Acc:HGNC:28404]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030234//enzyme regulator activity;GO:0031267//small GTPase binding;GO:1901981//phosphatidylinositol phosphate binding	GO:0006897//endocytosis;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0043547//positive regulation of GTPase activity;GO:0050776//regulation of immune response;GO:0050790//regulation of catalytic activity;GO:0050852//T cell receptor signaling pathway;GO:2000553//positive regulation of T-helper 2 cell cytokine production	--
ENSG00000213064	3.555	2.976	3.288	2.81	3.034	3.217	814	685	556	406	587	536	SFT2D2	SFT2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25140]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000213066	4.173	3.867	3.806	3.076	2.445	3.017	206	172	122	105	101	117	CEP43	centrosomal protein 43 [Source:HGNC Symbol;Acc:HGNC:17012]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005814//centriole;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0042803//protein homodimerization activity	GO:0006469//negative regulation of protein kinase activity;GO:0008284//positive regulation of cell population proliferation;GO:0030030//cell projection organization;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0034453//microtubule anchoring;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000213079	11.733	12.17	10.934	8.019	9.906	10.964	1235	1282.83	857.12	628.8	886.99	844.79	SCAF8	SR-related CTD associated factor 8 [Source:HGNC Symbol;Acc:HGNC:20959]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005849//mRNA cleavage factor complex;GO:0016363//nuclear matrix	GO:0000993//RNA polymerase II complex binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043175//RNA polymerase core enzyme binding;GO:1990269//RNA polymerase II C-terminal domain phosphoserine binding	"GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:2000805//negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled"	--
ENSG00000213085	0.654	0.798	0.496	0.247	0.341	0.036	25	27	14	7	6	1	CFAP45	cilia and flagella associated protein 45 [Source:HGNC Symbol;Acc:HGNC:17229]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection;GO:0097728//9+0 motile cilium;GO:0097729//9+2 motile cilium	GO:0005515//protein binding;GO:0016208//AMP binding	GO:0030317//flagellated sperm motility;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0061966//establishment of left/right asymmetry;GO:0090660//cerebrospinal fluid circulation	--
ENSG00000213088	0.126	0	0	0	0.05	0.035	3	0	0	0	1	1	ACKR1	atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035]	Human Diseases	Infectious disease: parasitic	ko05144//Malaria	K06574	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0019956//chemokine binding;GO:0019957//C-C chemokine binding;GO:0038023//signaling receptor activity	GO:0006952//defense response;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0032642//regulation of chemokine production;GO:0070098//chemokine-mediated signaling pathway	--
ENSG00000213096	7.957	6.455	6.629	6.228	5.052	5.328	632.62	490	372	291	319.03	302.66	ZNF254	zinc finger protein 254 [Source:HGNC Symbol;Acc:HGNC:13047]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213123	12.239	9.368	8.284	8.171	6.509	9.024	161	123.39	81	81	74	88.66	DYNLT2B	dynein light chain Tctex-type 2B [Source:HGNC Symbol;Acc:HGNC:28482]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex;GO:0005929//cilium;GO:0005930//axoneme;GO:0031021//interphase microtubule organizing center;GO:0097546//ciliary base;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding	GO:0007018//microtubule-based movement;GO:0035721//intraciliary retrograde transport;GO:0060271//cilium assembly;GO:1902017//regulation of cilium assembly;GO:1905799//regulation of intraciliary retrograde transport	--
ENSG00000213139	0.628	0.341	0.541	1.003	0.406	0.55	11	6	7	13	6	7	CRYGS	crystallin gamma S [Source:HGNC Symbol;Acc:HGNC:2417]	-	-	-	-	-	GO:0005212//structural constituent of eye lens;GO:0005515//protein binding	GO:0002009//morphogenesis of an epithelium;GO:0002088//lens development in camera-type eye;GO:0007601//visual perception	--
ENSG00000213145	0.717	1.927	1.063	3.721	2.321	3.254	10	27	11.53	38.42	29	33	CRIP1	cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360]	-	-	-	-	GO:0005737//cytoplasm	GO:0008270//zinc ion binding;GO:0042277//peptide binding;GO:0046872//metal ion binding	GO:0006955//immune response;GO:0007507//heart development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010033//response to organic substance;GO:0010043//response to zinc ion;GO:0010468//regulation of gene expression;GO:0060741//prostate gland stromal morphogenesis;GO:0071236//cellular response to antibiotic;GO:0071493//cellular response to UV-B	--
ENSG00000213160	3.41	2.334	3.484	2.453	3.317	2.83	224	185.31	169.58	149.15	166.28	156.03	KLHL23	kelch like family member 23 [Source:HGNC Symbol;Acc:HGNC:27506]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000213171	0.182	0.29	0.099	0.295	0.086	0.05	10	16	4	12	4	2	LINGO4	leucine rich repeat and Ig domain containing 4 [Source:HGNC Symbol;Acc:HGNC:31814]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000213185	0	0	0	0	0	0	0	0	0	0	0	0	FAM24B	family with sequence similarity 24 member B [Source:HGNC Symbol;Acc:HGNC:23475]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000213186	2.886	2.667	1.919	1.354	1.707	2.58	231.08	180.31	112.42	80.7	115.02	100.52	TRIM59	tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell	--
ENSG00000213190	9.902	9.755	9.596	7.287	7.147	7.926	510	505	365	278	311	297	MLLT11	MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton	GO:0003674//molecular_function;GO:0005515//protein binding	"GO:0043065//positive regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051901//positive regulation of mitochondrial depolarization;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway"	--
ENSG00000213199	0.427	0.184	0.4	0.444	0.637	0.635	16	8	5	8	22	20	ASIC3	acid sensing ion channel subunit 3 [Source:HGNC Symbol;Acc:HGNC:101]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04830	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005261//cation channel activity;GO:0005272//sodium channel activity;GO:0015280//ligand-gated sodium channel activity;GO:0042931//enterobactin transmembrane transporter activity;GO:0044736//acid-sensing ion channel activity	GO:0006811//ion transport;GO:0006812//cation transport;GO:0006814//sodium ion transport;GO:0007165//signal transduction;GO:0007600//sensory perception;GO:0009408//response to heat;GO:0009612//response to mechanical stimulus;GO:0010447//response to acidic pH;GO:0034220//ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0042930//enterobactin transport;GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0050915//sensory perception of sour taste;GO:0050961//detection of temperature stimulus involved in sensory perception;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0050968//detection of chemical stimulus involved in sensory perception of pain;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0098655//cation transmembrane transport	--
ENSG00000213203	0	0	0	0	0.013	0	0	0	0	0	1	0	GIMAP1	"GTPase, IMAP family member 1 [Source:HGNC Symbol;Acc:HGNC:23237]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005525//GTP binding	-	--
ENSG00000213204	0	0.215	0	0	0	0	0	10.33	0	0	0	0	CFAP206	"novel transcript, C6orf165-SLC35A1 readthrough"	-	-	-	-	-	-	-	--
ENSG00000213213	0.365	0.335	0.266	0.228	0.379	0.27	13	12	7	6	11.41	7	CCDC183	coiled-coil domain containing 183 [Source:HGNC Symbol;Acc:HGNC:28236]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000213214	5.397	5.235	5.465	4.908	5.393	5.457	284.46	280.49	211.24	187.52	246.56	209.42	ARHGEF35	Rho guanine nucleotide exchange factor 35 [Source:HGNC Symbol;Acc:HGNC:33846]	-	-	-	-	-	-	-	--
ENSG00000213215	0	0	0	0	0	0	0	0	0	0	0	0	OR2F1	olfactory receptor family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:8246]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000213218	0	0	0	0	0	0	0	0	0	0	0	0	CSH2	chorionic somatomammotropin hormone 2 [Source:HGNC Symbol;Acc:HGNC:2441]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle	GO:0005131//growth hormone receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0031667//response to nutrient levels;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0060396//growth hormone receptor signaling pathway	--
ENSG00000213221	1.127	1.187	1.069	1.321	1.223	1.405	72.36	76.59	50.69	62.84	66.33	65.65	DNLZ	DNL-type zinc finger [Source:HGNC Symbol;Acc:HGNC:33879]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding	GO:0006457//protein folding;GO:0030150//protein import into mitochondrial matrix;GO:0050821//protein stabilization	--
ENSG00000213231	0	0	0	0	0	0	0	0	0	0	0	0	TCL1B	TCL1 family AKT coactivator B [Source:HGNC Symbol;Acc:HGNC:11649]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K16836	GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000213246	33.29	29.06	34.03	33.505	30.412	33.948	905.55	908	767	774.3	804	690	SUPT4H1	"SPT4 homolog, DSIF elongation factor subunit [Source:HGNC Symbol;Acc:HGNC:11467]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032044//DSIF complex	GO:0000993//RNA polymerase II complex binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0032785//negative regulation of DNA-templated transcription, elongation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription by RNA polymerase II"	--
ENSG00000213265	0	0	0	0	0	0	0	0	0	0	0	0	TSGA13	testis specific 13 [Source:HGNC Symbol;Acc:HGNC:12369]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000213281	19.815	17.286	17.051	15.211	15.183	16.848	1778	1559	1130	1011	1151	1100	NRAS	"NRAS proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:7989]"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Signal transduction;Environmental adaptation;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Substance dependence;Immune system;Development and regeneration;Cancer: overview;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Nervous system;Nervous system;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Aging;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Transport and catabolism;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Aging;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828;K07828	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019003//GDP binding;GO:0044877//protein-containing complex binding	GO:0000165//MAPK cascade;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction	--
ENSG00000213297	1.819	1.826	1.61	1.159	1.039	0.825	100.01	92.84	62.97	47.21	48.27	33	ZNF625-ZNF20	ZNF625-ZNF20 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48368]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000213316	0	0	0	0	0	0	0	0	0	0	0	0	LTC4S	leukotriene C4 synthase [Source:HGNC Symbol;Acc:HGNC:6719]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K00807;K00807	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004364//glutathione transferase activity;GO:0004464//leukotriene-C4 synthase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0016740//transferase activity;GO:0016829//lyase activity;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0006691//leukotriene metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0050790//regulation of catalytic activity;GO:0098869//cellular oxidant detoxification	--
ENSG00000213337	6.124	8.094	8.95	8.508	7.804	8.716	128.52	168.74	134.62	130.5	146.27	130.5	ANKRD39	ankyrin repeat domain 39 [Source:HGNC Symbol;Acc:HGNC:28640]	-	-	-	-	GO:0005575//cellular_component;GO:0031436//BRCA1-BARD1 complex;GO:0070531//BRCA1-A complex	GO:0003674//molecular_function;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	GO:0008150//biological_process;GO:0085020//protein K6-linked ubiquitination	--
ENSG00000213339	9.637	9.48	8.71	11.764	12.19	10.224	263	263	179	241	286	208	QTRT1	queuine tRNA-ribosyltransferase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:23797]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:1990234//transferase complex	GO:0005515//protein binding;GO:0008479//queuine tRNA-ribosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016763//pentosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity	GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0101030//tRNA-guanine transglycosylation	--
ENSG00000213341	10.017	8.66	8.468	7.159	7.624	8.319	748	650	467	396	481	452	CHUK	component of inhibitor of nuclear factor kappa B kinase complex [Source:HGNC Symbol;Acc:HGNC:1974]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Signal transduction;Development and regeneration;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: specific types;Immune system;Cancer: overview;Immune system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune system;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04068//FoxO signaling pathway;ko04380//Osteoclast differentiation;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05221//Acute myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04623//Cytosolic DNA-sensing pathway;ko01523//Antifolate resistance	K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467;K04467	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008385//IkappaB kinase complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008384//IkappaB kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0097110//scaffold protein binding;GO:1990459//transferrin receptor binding	"GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007252//I-kappaB phosphorylation;GO:0009615//response to virus;GO:0009653//anatomical structure morphogenesis;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032727//positive regulation of interferon-alpha production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0038061//NIK/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071276//cellular response to cadmium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0098586//cellular response to virus"	--
ENSG00000213347	0.65	0.554	1.019	0.709	0.374	0.252	16.16	17.19	15.05	10.17	9.09	4	MXD3	MAX dimerization protein 3 [Source:HGNC Symbol;Acc:HGNC:14008]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	bHLH
ENSG00000213366	40.917	43.391	52.967	58.443	53.078	48.591	983.31	1053.23	946.87	962.37	1089.68	855.27	GSTM2	glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005102//signaling receptor binding;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding	GO:0006629//lipid metabolic process;GO:0006749//glutathione metabolic process;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0018916//nitrobenzene metabolic process;GO:0042178//xenobiotic catabolic process;GO:0043651//linoleic acid metabolic process;GO:0051122//hepoxilin biosynthetic process;GO:0055119//relaxation of cardiac muscle;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0070458//cellular detoxification of nitrogen compound;GO:0071313//cellular response to caffeine;GO:0098869//cellular oxidant detoxification;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000213380	19.938	19.826	21.387	19.438	20.698	22.825	1224.43	1135.54	948.21	924.42	1055.87	984.24	COG8	component of oligomeric golgi complex 8 [Source:HGNC Symbol;Acc:HGNC:18623]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex;GO:0032588//trans-Golgi network membrane	GO:0005515//protein binding	"GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0070085//glycosylation"	--
ENSG00000213390	2.571	2.1	2.817	1.735	3.41	1.88	223	219	205	145	210	146	ARHGAP19	Rho GTPase activating protein 19 [Source:HGNC Symbol;Acc:HGNC:23724]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000213397	4.295	5.68	3.511	4.857	3.874	4.461	112.53	148.56	70.25	97.45	88.65	87	HAUS7	HAUS augmin like complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:32979]	-	-	-	-	GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0031996//thioesterase binding;GO:0051011//microtubule minus-end binding	GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000213398	1.128	0.641	1.474	0.863	1.469	0.869	35	20	30.25	17	35	18	LCAT	lecithin-cholesterol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6522]	Metabolism;Organismal Systems	Lipid metabolism;Digestive system	ko00564//Glycerophospholipid metabolism;ko04979//Cholesterol metabolism	K00650;K00650	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular exosome	GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0004607//phosphatidylcholine-sterol O-acyltransferase activity;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0016787//hydrolase activity;GO:0034186//apolipoprotein A-I binding;GO:0047179//platelet-activating factor acetyltransferase activity	GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0034435//cholesterol esterification;GO:0042157//lipoprotein metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0046470//phosphatidylcholine metabolic process;GO:0046688//response to copper ion;GO:0051384//response to glucocorticoid;GO:0090107//regulation of high-density lipoprotein particle assembly	--
ENSG00000213401	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA12	MAGE family member A12 [Source:HGNC Symbol;Acc:HGNC:6799]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000213402	0.113	0.227	0.615	0.252	0.797	0.192	2.13	4.3	8.54	3.51	12.66	2.63	PTPRCAP	protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006952//defense response	--
ENSG00000213413	0	0	0	0	0	0	0	0	0	0	0	0	PVRIG	PVR related immunoglobulin domain containing [Source:HGNC Symbol;Acc:HGNC:32190]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0038023//signaling receptor activity	GO:0050860//negative regulation of T cell receptor signaling pathway	--
ENSG00000213416	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-12	keratin associated protein 4-12 [Source:HGNC Symbol;Acc:HGNC:16776]	-	-	-	-	GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000213417	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP2-4	keratin associated protein 2-4 [Source:HGNC Symbol;Acc:HGNC:18891]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000213420	0.652	1.168	1.098	0.571	0.672	0.521	31	43	25	13	21	20	GPC2	glypican 2 [Source:HGNC Symbol;Acc:HGNC:4450]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0045202//synapse;GO:0046658//anchored component of plasma membrane;GO:0062023//collagen-containing extracellular matrix	GO:0005515//protein binding	GO:0006024//glycosaminoglycan biosynthetic process;GO:0007224//smoothened signaling pathway;GO:0009966//regulation of signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0016477//cell migration;GO:0030182//neuron differentiation;GO:1905475//regulation of protein localization to membrane	--
ENSG00000213424	0	0.018	0	0	0	0	0	1	0	0	0	0	KRT222	keratin 222 [Source:HGNC Symbol;Acc:HGNC:28695]	-	-	-	-	GO:0005882//intermediate filament	GO:0005198//structural molecule activity;GO:0005515//protein binding	-	--
ENSG00000213439	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000213445	2.927	2.673	2.892	2.381	3.341	2.481	190	195	155	128	168	131	SIPA1	signal-induced proliferation-associated 1 [Source:HGNC Symbol;Acc:HGNC:10885]	Environmental Information Processing;Organismal Systems	Signal transduction;Immune system	ko04015//Rap1 signaling pathway;ko04670//Leukocyte transendothelial migration	K08013;K08013	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0030133//transport vesicle;GO:0032991//protein-containing complex;GO:0048471//perinuclear region of cytoplasm	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding	GO:0002250//adaptive immune response;GO:0007010//cytoskeleton organization;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0030308//negative regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0042631//cellular response to water deprivation;GO:0045786//negative regulation of cell cycle;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0090630//activation of GTPase activity	--
ENSG00000213462	10.02	9.589	7.752	7.813	10.097	7.17	666.3	640.96	380.74	384.84	567.28	346.93	ERV3-1	"endogenous retrovirus group 3 member 1, envelope [Source:HGNC Symbol;Acc:HGNC:3454]"	-	-	-	-	-	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000213463	8.176	6.818	7.511	4.68	5.878	6.268	1196.75	1003.17	812	507.41	726.86	667.52	SYNJ2BP	synaptojanin 2 binding protein [Source:HGNC Symbol;Acc:HGNC:18955]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0031307//integral component of mitochondrial outer membrane;GO:0031594//neuromuscular junction;GO:0043005//neuron projection;GO:0098839//postsynaptic density membrane	GO:0005515//protein binding	GO:0001937//negative regulation of endothelial cell proliferation;GO:0007268//chemical synaptic transmission;GO:0008593//regulation of Notch signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0043113//receptor clustering;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0097120//receptor localization to synapse;GO:0098609//cell-cell adhesion;GO:1903671//negative regulation of sprouting angiogenesis	--
ENSG00000213465	59.748	54.912	63.672	72.486	71.198	70.121	1145	1062	900	1028	1149	975	ARL2	ADP ribosylation factor like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:693]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0016328//lateral plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0006110//regulation of glycolytic process;GO:0006457//protein folding;GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0010811//positive regulation of cell-substrate adhesion;GO:0031113//regulation of microtubule polymerization;GO:0031116//positive regulation of microtubule polymerization;GO:0034260//negative regulation of GTPase activity;GO:0051457//maintenance of protein location in nucleus;GO:0070830//bicellular tight junction assembly;GO:1903715//regulation of aerobic respiration	--
ENSG00000213471	0.064	0.021	0	0.029	0.038	0.125	2	1	0	1	1	4.27	TTLL13P	"tubulin tyrosine ligase like 13, pseudogene [Source:HGNC Symbol;Acc:HGNC:32484]"	-	-	-	-	GO:0005829//cytosol;GO:0005874//microtubule;GO:0005929//cilium	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015631//tubulin binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070740//tubulin-glutamic acid ligase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0018095//protein polyglutamylation	--
ENSG00000213512	0	0	0	0	0.035	0	0	0	0	0	1	0	GBP7	guanylate binding protein 7 [Source:HGNC Symbol;Acc:HGNC:29606]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20899	GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity	GO:0001818//negative regulation of cytokine production;GO:0032480//negative regulation of type I interferon production;GO:0034345//negative regulation of type III interferon production;GO:0042832//defense response to protozoan;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045070//positive regulation of viral genome replication;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0050830//defense response to Gram-positive bacterium;GO:0051607//defense response to virus;GO:0071345//cellular response to cytokine stimulus;GO:0071346//cellular response to interferon-gamma	--
ENSG00000213516	6.844	7.367	6.242	7.93	6.602	6.939	683.22	749.43	465.44	549	554.77	469.35	RBMXL1	RBMX like 1 [Source:HGNC Symbol;Acc:HGNC:25073]	-	-	-	-	GO:0005634//nucleus;GO:0005681//spliceosomal complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000213523	11.254	12.75	13.763	13.821	10.957	13.322	310	353	280	282	255	267	SRA1	steroid receptor RNA activator 1 [Source:HGNC Symbol;Acc:HGNC:11281]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015630//microtubule cytoskeleton;GO:0031209//SCAR complex;GO:0031252//cell leading edge;GO:0045171//intercellular bridge;GO:1990904//ribonucleoprotein complex	GO:0002153//steroid receptor RNA activator RNA binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0007346//regulation of mitotic cell cycle;GO:0030154//cell differentiation;GO:0042981//regulation of apoptotic process;GO:0045662//negative regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071391//cellular response to estrogen stimulus"	--
ENSG00000213533	4.975	5.165	5.625	5.06	6.231	4.717	431.27	510.86	375.99	368.82	409.54	337.7	STIMATE	STIM activating enhancer [Source:HGNC Symbol;Acc:HGNC:30526]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032541//cortical endoplasmic reticulum;GO:0140268//endoplasmic reticulum-plasma membrane contact site	GO:0005246//calcium channel regulator activity;GO:0005515//protein binding	GO:0032237//activation of store-operated calcium channel activity;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade	--
ENSG00000213551	6.086	8.056	6.755	5.555	4.845	5.24	289.69	385.44	237.48	195.89	194.87	181.48	DNAJC9	DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0101031//chaperone complex	GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0042393//histone binding;GO:0051087//chaperone binding	GO:0006334//nucleosome assembly;GO:0032781//positive regulation of ATPase activity	--
ENSG00000213563	8.046	8.576	10.324	11.692	11.906	11.374	354	393	297	323	418	350	C8orf82	chromosome 8 open reading frame 82 [Source:HGNC Symbol;Acc:HGNC:33826]	-	-	-	-	-	-	-	--
ENSG00000213578	0.169	0.072	0.098	0.423	0.342	0.496	7	3	3	13	12	15	CPLX3	complexin 3 [Source:HGNC Symbol;Acc:HGNC:27652]	Organismal Systems	Nervous system	ko04721//Synaptic vesicle cycle	K15295	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0031201//SNARE complex;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0098684//photoreceptor ribbon synapse;GO:0098993//anchored component of synaptic vesicle membrane;GO:0099029//anchored component of presynaptic active zone membrane;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0019905//syntaxin binding	GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0007601//visual perception;GO:0016079//synaptic vesicle exocytosis;GO:0030073//insulin secretion;GO:0031630//regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0046928//regulation of neurotransmitter secretion;GO:0050896//response to stimulus	--
ENSG00000213585	83.788	84.177	88.872	86.965	88.32	80.511	3210	3248	2527	2480	2860	2257	VDAC1	voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Neurodegenerative disease;Immune system;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Cardiovascular disease;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Cell growth and death;Neurodegenerative disease;Digestive system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04020//Calcium signaling pathway;ko05020//Prion disease;ko05012//Parkinson disease;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05166//Human T-cell leukemia virus 1 infection;ko05415//Diabetic cardiomyopathy;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko05017//Spinocerebellar ataxia;ko04979//Cholesterol metabolism	K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862;K05862	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005757//mitochondrial permeability transition pore complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0042645//mitochondrial nucleoid;GO:0045121//membrane raft;GO:0046930//pore complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008308//voltage-gated anion channel activity;GO:0015288//porin activity;GO:0015485//cholesterol binding;GO:0019901//protein kinase binding;GO:0031210//phosphatidylcholine binding;GO:0044325//transmembrane transporter binding;GO:0097001//ceramide binding	GO:0006090//pyruvate metabolic process;GO:0006811//ion transport;GO:0006820//anion transport;GO:0006915//apoptotic process;GO:0015698//inorganic anion transport;GO:0030855//epithelial cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0055085//transmembrane transport;GO:0098656//anion transmembrane transport;GO:0110099//negative regulation of calcium import into the mitochondrion;GO:1903146//regulation of autophagy of mitochondrion;GO:1905091//positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	--
ENSG00000213588	4.919	5.902	6.819	6.915	6.201	6.126	277	326	266	269	286	251	ZBTB9	zinc finger and BTB domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28323]	-	-	-	-	GO:0005634//nucleus	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000213593	69.185	70.954	75.768	78.51	74.211	87.647	2320.5	2375.31	1885.92	1964.05	2128.49	2123.9	TMX2	thioredoxin related transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30739]	-	-	-	-	GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0043227//membrane-bounded organelle;GO:0044233//mitochondria-associated endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0015036//disulfide oxidoreductase activity;GO:0042802//identical protein binding	GO:0007420//brain development	--
ENSG00000213614	114.133	135.376	122.171	131.382	116.746	113.431	3986.66	4737.72	3156.75	3392.75	3455.84	2921.85	HEXA	hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878]	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00520//Amino sugar and nucleotide sugar metabolism;ko00513//Various types of N-glycan biosynthesis;ko00531//Glycosaminoglycan degradation;ko00511//Other glycan degradation;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K12373;K12373;K12373;K12373;K12373;K12373;K12373;K12373	GO:0005764//lysosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0042582//azurophil granule;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:1905379//beta-N-acetylhexosaminidase complex	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0005515//protein binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046982//protein heterodimerization activity;GO:0102148//N-acetyl-beta-D-galactosaminidase activity"	GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006629//lipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0008152//metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:1901135//carbohydrate derivative metabolic process	--
ENSG00000213619	33.675	38.078	37.364	36.619	37.071	34.858	603	682	486	487	549	451	NDUFS3	NADH:ubiquinone oxidoreductase core subunit S3 [Source:HGNC Symbol;Acc:HGNC:7710]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936;K03936	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016604//nuclear body;GO:0031966//mitochondrial membrane;GO:0070469//respirasome	"GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity;GO:0016491//oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H"	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0021762//substantia nigra development;GO:0030308//negative regulation of cell growth;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0072593//reactive oxygen species metabolic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway"	--
ENSG00000213625	29.842	27.672	30.499	30.675	31.303	33.273	2629.99	2385.95	1990.76	1914	2225.22	2192	LEPROT	leptin receptor overlapping transcript [Source:HGNC Symbol;Acc:HGNC:29477]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0046426//negative regulation of receptor signaling pathway via JAK-STAT;GO:0060400//negative regulation of growth hormone receptor signaling pathway;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000213626	142.984	149.311	136.252	121.979	122.78	120.325	6655	6732	4469	3952	4734	4009	LBH	LBH regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:29532]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032991//protein-containing complex	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0030879//mammary gland development;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060644//mammary gland epithelial cell differentiation;GO:1904674//positive regulation of somatic stem cell population maintenance;GO:1904677//positive regulation of somatic stem cell division;GO:2000103//positive regulation of mammary stem cell proliferation;GO:2000737//negative regulation of stem cell differentiation"	--
ENSG00000213638	1.327	1.14	1.551	2.117	2.026	2.984	44	38	38	50.71	56	72	ADAT3	adenosine deaminase tRNA specific 3 [Source:HGNC Symbol;Acc:HGNC:25151]	-	-	-	-	-	GO:0003824//catalytic activity	-	--
ENSG00000213639	48.753	44.06	41.679	34.673	32.454	41.578	3486	3093	2205	1699	1985	2196	PPP1CB	protein phosphatase 1 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9282]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Genetic Information Processing;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Signal transduction;Cell motility;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Substance dependence;Signal transduction;Cell growth and death;Signal transduction;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Circulatory system;Nervous system;Immune system;Endocrine and metabolic disease;Translation;Sensory system;Substance dependence;Nervous system	ko05168//Herpes simplex virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04611//Platelet activation;ko04931//Insulin resistance;ko03015//mRNA surveillance pathway;ko04750//Inflammatory mediator regulation of TRP channels;ko05031//Amphetamine addiction;ko04720//Long-term potentiation	K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269;K06269	"GO:0000164//protein phosphatase type 1 complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0042587//glycogen granule;GO:0070062//extracellular exosome;GO:0072357//PTW/PP1 phosphatase complex"	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017018//myosin phosphatase activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0050115//myosin-light-chain-phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000165//MAPK cascade;GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0005981//regulation of glycogen catabolic process;GO:0006470//protein dephosphorylation;GO:0007049//cell cycle;GO:0030155//regulation of cell adhesion;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0043153//entrainment of circadian clock by photoperiod;GO:0048511//rhythmic process;GO:0051301//cell division	--
ENSG00000213648	0.688	0.526	0.995	0.51	0.367	0.893	11.83	10.04	12.52	6.05	5.94	10.69	SULT1A4	sulfotransferase family 1A member 4 [Source:HGNC Symbol;Acc:HGNC:30004]	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K01014	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0006584//catecholamine metabolic process;GO:0006629//lipid metabolic process;GO:0008202//steroid metabolic process;GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000213654	0	0.082	0.388	0.111	0.242	0	0	2	7	2	5	0	GPSM3	G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:13945]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005886//plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0002690//positive regulation of leukocyte chemotaxis;GO:0008150//biological_process;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050790//regulation of catalytic activity;GO:1900017//positive regulation of cytokine production involved in inflammatory response	--
ENSG00000213658	0.133	0.199	0.155	0.083	0.413	0.371	4	6	3	1	8	6	LAT	linker for activation of T cells [Source:HGNC Symbol;Acc:HGNC:18874]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Infectious disease: bacterial;Immune system;Signal transduction;Immune system;Immune system;Immune system;Immune system;Immune system;Cancer: overview	ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04664//Fc epsilon RI signaling pathway;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer	K07362;K07362;K07362;K07362;K07362;K07362;K07362;K07362;K07362;K07362;K07362	GO:0001772//immunological synapse;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0008180//COP9 signalosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030159//signaling receptor complex adaptor activity	GO:0002250//adaptive immune response;GO:0002260//lymphocyte homeostasis;GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007265//Ras protein signal transduction;GO:0010467//gene expression;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0043303//mast cell degranulation;GO:0045860//positive regulation of protein kinase activity;GO:0048872//homeostasis of number of cells;GO:0050863//regulation of T cell activation	--
ENSG00000213672	7.346	8.053	9.579	8.161	8.921	8.233	367	379	343	322	428	332	NCKIPSD	NCK interacting protein with SH3 domain [Source:HGNC Symbol;Acc:HGNC:15486]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0008180//COP9 signalosome	GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0017124//SH3 domain binding;GO:0071933//Arp2/3 complex binding	GO:0006897//endocytosis;GO:0007010//cytoskeleton organization;GO:0010976//positive regulation of neuron projection development	--
ENSG00000213676	32.03	35.032	34.794	34.202	38.732	34.648	1743	1915	1395	1376	1778	1372	ATF6B	activating transcription factor 6 beta [Source:HGNC Symbol;Acc:HGNC:2349]	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	"Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Substance dependence;Signal transduction;Folding, sorting and degradation;Infectious disease: viral;Endocrine and metabolic disease;Circulatory system;Endocrine system;Nervous system;Endocrine system;Endocrine system;Signal transduction;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Substance dependence;Endocrine system;Substance dependence"	"ko04151//PI3K-Akt signaling pathway;ko05020//Prion disease;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko05161//Hepatitis B;ko04934//Cushing syndrome;ko04261//Adrenergic signaling in cardiomyocytes;ko04915//Estrogen signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04668//TNF signaling pathway;ko04928//Parathyroid hormone synthesis, secretion and action;ko04925//Aldosterone synthesis and secretion;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04918//Thyroid hormone synthesis;ko05031//Amphetamine addiction;ko04927//Cortisol synthesis and secretion;ko05030//Cocaine addiction"	K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049;K09049	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032993//protein-DNA complex;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0035497//cAMP response element binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006986//response to unfolded protein;GO:0007165//signal transduction;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1903892//negative regulation of ATF6-mediated unfolded protein response;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress"	TF_bZIP
ENSG00000213689	10.526	12.475	13.065	14.622	12.176	14.963	225.1	250.78	209.5	238.57	216.38	223.94	TREX1	three prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:12269]	Organismal Systems	Immune system	ko04623//Cytosolic DNA-sensing pathway	K10790	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032993//protein-DNA complex;GO:0043596//nuclear replication fork	"GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0004518//nuclease activity;GO:0004527//exonuclease activity;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0008301//DNA binding, bending;GO:0008408//3'-5' exonuclease activity;GO:0008853//exodeoxyribonuclease III activity;GO:0016787//hydrolase activity;GO:0032405//MutLalpha complex binding;GO:0032407//MutSalpha complex binding;GO:0032558//adenyl deoxyribonucleotide binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0050699//WW domain binding"	"GO:0000077//DNA damage checkpoint signaling;GO:0000738//DNA catabolic process, exonucleolytic;GO:0001568//blood vessel development;GO:0001822//kidney development;GO:0002250//adaptive immune response;GO:0002251//organ or tissue specific immune response;GO:0002253//activation of immune response;GO:0002281//macrophage activation involved in immune response;GO:0002320//lymphoid progenitor cell differentiation;GO:0002383//immune response in brain or nervous system;GO:0002437//inflammatory response to antigenic stimulus;GO:0002457//T cell antigen processing and presentation;GO:0002637//regulation of immunoglobulin production;GO:0003007//heart morphogenesis;GO:0003015//heart process;GO:0003228//atrial cardiac muscle tissue development;GO:0006091//generation of precursor metabolites and energy;GO:0006110//regulation of glycolytic process;GO:0006259//DNA metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006304//DNA modification;GO:0006308//DNA catabolic process;GO:0006310//DNA recombination;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0008340//determination of adult lifespan;GO:0009411//response to UV;GO:0010468//regulation of gene expression;GO:0019217//regulation of fatty acid metabolic process;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0032197//transposition, RNA-mediated;GO:0032479//regulation of type I interferon production;GO:0032508//DNA duplex unwinding;GO:0032680//regulation of tumor necrosis factor production;GO:0034599//cellular response to oxidative stress;GO:0034614//cellular response to reactive oxygen species;GO:0034644//cellular response to UV;GO:0035458//cellular response to interferon-beta;GO:0035781//CD86 biosynthetic process;GO:0043277//apoptotic cell clearance;GO:0043457//regulation of cellular respiration;GO:0045087//innate immune response;GO:0045088//regulation of innate immune response;GO:0045184//establishment of protein localization;GO:0045824//negative regulation of innate immune response;GO:0046890//regulation of lipid biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0050790//regulation of catalytic activity;GO:0050821//protein stabilization;GO:0050863//regulation of T cell activation;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0061635//regulation of protein complex stability;GO:0071310//cellular response to organic substance;GO:0071357//cellular response to type I interferon;GO:0071480//cellular response to gamma radiation;GO:0072711//cellular response to hydroxyurea;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0097281//immune complex formation;GO:1904161//DNA synthesis involved in UV-damage excision repair;GO:1905671//regulation of lysosome organization"	--
ENSG00000213694	2.714	2.014	1.946	0.616	0.83	1.282	244	182	130	41	63	84	S1PR3	sphingosine-1-phosphate receptor 3 [Source:HGNC Symbol;Acc:HGNC:3167]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04071//Sphingolipid signaling pathway	K04290;K04290	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0038036//sphingosine-1-phosphate receptor activity	GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007219//Notch signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0009653//anatomical structure morphogenesis;GO:0019222//regulation of metabolic process;GO:0032651//regulation of interleukin-1 beta production;GO:1903141//negative regulation of establishment of endothelial barrier	--
ENSG00000213699	13.95	14.288	16.414	14.85	14.057	17.214	1128	1159	978	887	957	1011	SLC35F6	solute carrier family 35 member F6 [Source:HGNC Symbol;Acc:HGNC:26055]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0008284//positive regulation of cell population proliferation;GO:0055085//transmembrane transport;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	--
ENSG00000213714	0.347	0	0	0	0	0	5	0	0	0	0	0	FAM209B	family with sequence similarity 209 member B [Source:HGNC Symbol;Acc:HGNC:16101]	-	-	-	-	GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000213719	57.824	62.247	60.84	63.2	61.786	56.745	1435	1551	1116	1162	1295	1025	CLIC1	chloride intracellular channel 1 [Source:HGNC Symbol;Acc:HGNC:2062]	-	-	-	-	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0031982//vesicle;GO:0034707//chloride channel complex;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0006749//glutathione metabolic process;GO:0006811//ion transport;GO:0006821//chloride transport;GO:0007165//signal transduction;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0045669//positive regulation of osteoblast differentiation;GO:0051726//regulation of cell cycle;GO:0051881//regulation of mitochondrial membrane potential;GO:0070527//platelet aggregation	--
ENSG00000213722	31.546	36.746	32.586	30.94	32.183	27.525	813	948	622	592	692	514	DDAH2	dimethylarginine dimethylaminohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:2716]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016403//dimethylargininase activity;GO:0016597//amino acid binding;GO:0016787//hydrolase activity	GO:0000052//citrulline metabolic process;GO:0006525//arginine metabolic process;GO:0006527//arginine catabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050999//regulation of nitric-oxide synthase activity	--
ENSG00000213741	113.535	116.1	98.776	104.035	87.351	84.968	746	772	476	502	485	412	RPS29	ribosomal protein S29 [Source:HGNC Symbol;Acc:HGNC:10419]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02980;K02980	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0022627//cytosolic small ribosomal subunit;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane;GO:0110165//cellular anatomical entity	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000213759	0	0	0	0	0.027	0	0	0	0	0	1	0	UGT2B11	UDP glucuronosyltransferase family 2 member B11 [Source:HGNC Symbol;Acc:HGNC:12545]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006805//xenobiotic metabolic process;GO:0008210//estrogen metabolic process;GO:0052697//xenobiotic glucuronidation	--
ENSG00000213760	0.926	0.799	0.334	0.847	0.833	0.812	20	15	7	15	20	13	ATP6V1G2	ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152;K02152	"GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005829//cytosol;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0042470//melanosome"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0016241//regulation of macroautophagy;GO:1902600//proton transmembrane transport	--
ENSG00000213762	5.033	4.647	4.865	6.199	4.728	5.875	514	459	367	405	408	370	ZNF134	zinc finger protein 134 [Source:HGNC Symbol;Acc:HGNC:12918]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000213780	5.253	5.983	5.305	5.82	7.116	7.608	186	213	139	153	213	196	GTF2H4	general transcription factor IIH subunit 4 [Source:HGNC Symbol;Acc:HGNC:4658]	Human Diseases;Genetic Information Processing;Genetic Information Processing	Cancer: overview;Transcription;Replication and repair	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K03144;K03144;K03144	GO:0000438//core TFIIH complex portion of holo TFIIH complex;GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0016607//nuclear speck	GO:0001671//ATPase activator activity;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity	GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006366//transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000213782	26.69	27.908	28.199	26.684	25.041	30.912	1005.89	1052.71	766.96	744.92	796.22	829.87	DDX47	DEAD-box helicase 47 [Source:HGNC Symbol;Acc:HGNC:18682]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0006364//rRNA processing;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0008380//RNA splicing;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors	--
ENSG00000213793	0.937	0.756	0.677	0.55	0.84	0.72	80.57	65.31	43	35	61	45	ZNF888	zinc finger protein 888 [Source:HGNC Symbol;Acc:HGNC:38695]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213799	1.926	1.055	1.284	0.654	1.095	1.012	191	114	103	50	94	70	ZNF845	zinc finger protein 845 [Source:HGNC Symbol;Acc:HGNC:25112]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213809	0	0	0	0	0.06	0	0	0	0	0	1	0	KLRK1	killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788]	Organismal Systems;Human Diseases	Immune system;Infectious disease: parasitic	ko04650//Natural killer cell mediated cytotoxicity;ko05144//Malaria	K06728;K06728	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0032394//MHC class Ib receptor activity;GO:0038023//signaling receptor activity;GO:0042288//MHC class I protein binding;GO:0042802//identical protein binding	GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0030101//natural killer cell activation;GO:0030154//cell differentiation;GO:0031295//T cell costimulation;GO:0032729//positive regulation of interferon-gamma production;GO:0034260//negative regulation of GTPase activity;GO:0042267//natural killer cell mediated cytotoxicity;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0071222//cellular response to lipopolysaccharide;GO:2000502//negative regulation of natural killer cell chemotaxis	--
ENSG00000213822	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM18	CEA cell adhesion molecule 18 [Source:HGNC Symbol;Acc:HGNC:31949]	-	-	-	-	-	-	-	--
ENSG00000213853	54.204	58.19	50.871	43.748	46.119	46.509	4136	4569	3126	2777	3227	2555	EMP2	epithelial membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:3334]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045121//membrane raft;GO:0045177//apical part of cell	GO:0005178//integrin binding;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding	GO:0001765//membrane raft assembly;GO:0001913//T cell mediated cytotoxicity;GO:0001952//regulation of cell-matrix adhesion;GO:0001954//positive regulation of cell-matrix adhesion;GO:0003093//regulation of glomerular filtration;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007566//embryo implantation;GO:0008219//cell death;GO:0008284//positive regulation of cell population proliferation;GO:0010594//regulation of endothelial cell migration;GO:0016477//cell migration;GO:0032060//bleb assembly;GO:0032147//activation of protein kinase activity;GO:0034394//protein localization to cell surface;GO:0043534//blood vessel endothelial cell migration;GO:0043549//regulation of kinase activity;GO:0045022//early endosome to late endosome transport;GO:0045765//regulation of angiogenesis;GO:0070252//actin-mediated cell contraction;GO:0072659//protein localization to plasma membrane;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:2001212//regulation of vasculogenesis	--
ENSG00000213859	8.743	8.401	8.391	8.786	11.062	8.68	510	498	363	381	550	369	KCTD11	potassium channel tetramerization domain containing 11 [Source:HGNC Symbol;Acc:HGNC:21302]	-	-	-	-	-	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0042802//identical protein binding	GO:0007049//cell cycle;GO:0016567//protein ubiquitination;GO:0040008//regulation of growth;GO:0045666//positive regulation of neuron differentiation;GO:0051260//protein homooligomerization	--
ENSG00000213886	0.971	1.059	1.426	1.065	0.679	1.244	18	19.74	19.53	14.63	10.63	16.79	UBD	ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016235//aggresome	GO:0005515//protein binding;GO:0070628//proteasome binding	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:0043011//myeloid dendritic cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070842//aggresome assembly;GO:1901990//regulation of mitotic cell cycle phase transition	--
ENSG00000213889	0.188	0.062	0.171	0.169	0	0	3	1	2	2	0	0	PPM1N	"protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) [Source:HGNC Symbol;Acc:HGNC:26845]"	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000213892	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM16	"CEA cell adhesion molecule 16, tectorial membrane component [Source:HGNC Symbol;Acc:HGNC:31948]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0032426//stereocilium tip	GO:0042802//identical protein binding	GO:0007605//sensory perception of sound	--
ENSG00000213901	0	0	0	0	0.028	0	0	0	0	0	1	0	SLC23A3	solute carrier family 23 member 3 [Source:HGNC Symbol;Acc:HGNC:20601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015229//L-ascorbic acid transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0015882//L-ascorbic acid transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000213903	0.364	0.292	0.999	0.606	0.417	0.177	31	25	17	27	30	11	LTB4R	leukotriene B4 receptor [Source:HGNC Symbol;Acc:HGNC:6713]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04296	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0001632//leukotriene B4 receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004974//leukotriene receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0006936//muscle contraction;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0061737//leukotriene signaling pathway	--
ENSG00000213906	0.498	0.618	0.539	0.7	0.489	0.181	21.7	34.67	23.06	19	19.71	8.46	LTB4R2	leukotriene B4 receptor 2 [Source:HGNC Symbol;Acc:HGNC:19260]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K04297;K04297	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001632//leukotriene B4 receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004974//leukotriene receptor activity;GO:0008528//G protein-coupled peptide receptor activity	GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007218//neuropeptide signaling pathway;GO:0051546//keratinocyte migration;GO:0061737//leukotriene signaling pathway	--
ENSG00000213918	5.969	2.764	2.47	3.81	4.499	4.584	247.11	194.1	156.07	144.04	205.06	169.15	DNASE1	deoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:2956]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0031410//cytoplasmic vesicle;GO:0042588//zymogen granule;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0003779//actin binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004530//deoxyribonuclease I activity;GO:0004536//deoxyribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0000737//DNA catabolic process, endonucleolytic;GO:0002283//neutrophil activation involved in immune response;GO:0002673//regulation of acute inflammatory response;GO:0006308//DNA catabolic process;GO:0006915//apoptotic process;GO:0070948//regulation of neutrophil mediated cytotoxicity"	--
ENSG00000213920	4.105	6.103	5.809	5.579	4.711	3.574	61.56	92	62.86	61.97	59	39	MDP1	magnesium dependent phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28781]	-	-	-	-	-	GO:0003993//acid phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000213921	0	0	0	0	0	0	0	0	0	0	0	0	LEUTX	leucine twenty homeobox [Source:HGNC Symbol;Acc:HGNC:31953]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000213923	57.577	60.516	57.266	64.858	71.908	59.662	2471.72	2553.38	1770.93	1987.48	2362.95	1864.2	CSNK1E	casein kinase 1 epsilon [Source:HGNC Symbol;Acc:HGNC:2453]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Environmental adaptation;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko04390//Hippo signaling pathway;ko04068//FoxO signaling pathway;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm;ko04392//Hippo signaling pathway - multiple species	K08960;K08960;K08960;K08960;K08960;K08960;K08960;K08960	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0032091//negative regulation of protein binding;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032880//regulation of protein localization;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0060070//canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1905426//positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway	--
ENSG00000213927	0	0.115	0	0	0	0	0	1	0	0	0	0	CCL27	C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K16598;K16598;K16598	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031728//CCR3 chemokine receptor binding	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0010820//positive regulation of T cell chemotaxis;GO:0060326//cell chemotaxis;GO:2000251//positive regulation of actin cytoskeleton reorganization	--
ENSG00000213928	36.82	38.458	43.442	40.721	42.782	54.921	846.3	891.34	754.53	787.17	858.33	936.1	IRF9	interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04625//C-type lectin receptor signaling pathway	K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693;K04693	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070721//ISGF3 complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002376//immune system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007166//cell surface receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051607//defense response to virus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway"	IRF
ENSG00000213930	5.686	6.867	6.419	7.919	7.84	8.753	189.3	223.5	155.95	179.85	204.01	210.65	GALT	galactose-1-phosphate uridylyltransferase [Source:HGNC Symbol;Acc:HGNC:4135]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Endocrine system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04917//Prolactin signaling pathway;ko00520//Amino sugar and nucleotide sugar metabolism;ko00052//Galactose metabolism	K00965;K00965;K00965;K00965	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol	GO:0005515//protein binding;GO:0008108//UDP-glucose:hexose-1-phosphate uridylyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006011//UDP-glucose metabolic process;GO:0006012//galactose metabolic process;GO:0006258//UDP-glucose catabolic process;GO:0019388//galactose catabolic process;GO:0033499//galactose catabolic process via UDP-galactose	--
ENSG00000213931	0	0	0	0	0	0	0	0	0	0	0	0	HBE1	hemoglobin subunit epsilon 1 [Source:HGNC Symbol;Acc:HGNC:4830]	-	-	-	-	GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex;GO:0072562//blood microparticle	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0031721//hemoglobin alpha binding;GO:0043177//organic acid binding;GO:0044877//protein-containing complex binding;GO:0046872//metal ion binding	GO:0014070//response to organic cyclic compound;GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000213934	0	0	0	0	0	0	0	0	0	0	0	0	HBG1	hemoglobin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:4831]	-	-	-	-	GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0031721//hemoglobin alpha binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000213937	0	0	0	0	0	0	0	0	0	0	0	0	CLDN9	claudin 9 [Source:HGNC Symbol;Acc:HGNC:2051]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle	GO:0001618//virus receptor activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045216//cell-cell junction organization;GO:0046718//viral entry into host cell;GO:0070830//bicellular tight junction assembly;GO:0120193//tight junction organization	--
ENSG00000213949	3.028	2.535	1.328	0.468	0.806	0.668	526.85	438.76	175.98	62.17	114.72	85.35	ITGA1	integrin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6134]	Environmental Information Processing;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Infectious disease: viral;Cell motility;Cellular community - eukaryotes;Immune system;Cardiovascular disease;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06480;K06480;K06480;K06480;K06480;K06480;K06480;K06480;K06480	GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034665//integrin alpha1-beta1 complex;GO:0043005//neuron projection;GO:0043204//perikaryon;GO:0045121//membrane raft;GO:0045178//basal part of cell;GO:0070062//extracellular exosome	GO:0005102//signaling receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005518//collagen binding;GO:0019903//protein phosphatase binding;GO:0046872//metal ion binding;GO:0098639//collagen binding involved in cell-matrix adhesion	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0030593//neutrophil chemotaxis;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0033627//cell adhesion mediated by integrin;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0042311//vasodilation;GO:0043410//positive regulation of MAPK cascade;GO:0043525//positive regulation of neuron apoptotic process;GO:0045123//cellular extravasation;GO:0048812//neuron projection morphogenesis;GO:0060326//cell chemotaxis;GO:0098609//cell-cell adhesion	--
ENSG00000213965	4.335	3.617	4.733	4.132	5.131	5.338	279	234	225	197	279	250	NUDT19	nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13355	GO:0005575//cellular_component;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0010945//CoA pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0008150//biological_process;GO:0009062//fatty acid catabolic process;GO:0015938//coenzyme A catabolic process;GO:0036114//medium-chain fatty-acyl-CoA catabolic process;GO:0044580//butyryl-CoA catabolic process;GO:1901289//succinyl-CoA catabolic process;GO:1902858//propionyl-CoA metabolic process;GO:2001294//malonyl-CoA catabolic process	--
ENSG00000213967	1.178	0.727	0.74	0.305	0.584	0.967	34	25	19	9	16	18	ZNF726	zinc finger protein 726 [Source:HGNC Symbol;Acc:HGNC:32462]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213973	0	0	0	0	0	0	0	0	0	0	0	0	ZNF99	zinc finger protein 99 [Source:HGNC Symbol;Acc:HGNC:13175]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213977	39.162	39.099	40.202	43.453	41.394	42.325	1040.69	1043.93	788.98	854.88	928.7	818.14	TAX1BP3	Tax1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:30684]	-	-	-	-	GO:0001650//fibrillar center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0008022//protein C-terminus binding	GO:0007266//Rho protein signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0090630//activation of GTPase activity;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000213983	10.488	12.426	11.459	12.159	14.281	16.22	503.88	511.15	418.43	387.72	530.03	528.98	AP1G2	adaptor related protein complex 1 subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:556]	Human Diseases;Cellular Processes	Infectious disease: viral;Transport and catabolism	ko05170//Human immunodeficiency virus 1 infection;ko04142//Lysosome	K12391;K12391	GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030121//AP-1 adaptor complex;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0097708//intracellular vesicle;GO:0098588//bounding membrane of organelle	GO:0005515//protein binding;GO:0035615//clathrin adaptor activity;GO:0140312//cargo adaptor activity	GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006896//Golgi to vacuole transport;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000213988	0	0	0	0	0	0	0	0	0	0	0	0	ZNF90	zinc finger protein 90 [Source:HGNC Symbol;Acc:HGNC:13165]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000213995	16.713	18.006	19.877	17.391	18.197	19.425	870	944	710	663	791	725	NAXD	NAD(P)HX dehydratase [Source:HGNC Symbol;Acc:HGNC:25576]	-	-	-	-	GO:0005575//cellular_component;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016829//lyase activity;GO:0047453//ATP-dependent NAD(P)H-hydrate dehydratase activity;GO:0052855//ADP-dependent NAD(P)H-hydrate dehydratase activity	GO:0008150//biological_process;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0046496//nicotinamide nucleotide metabolic process;GO:0110051//metabolite repair	--
ENSG00000213996	0.572	0.916	0.387	0.257	0.677	0.306	18	29	9	6	18	7	TM6SF2	transmembrane 6 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11861]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006629//lipid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0055088//lipid homeostasis	--
ENSG00000213999	0.485	0.806	0.193	0.249	0.436	0.706	14.75	24.73	4.12	5.25	11.99	16.37	MEF2B	myocyte enhancer factor 2B [Source:HGNC Symbol;Acc:HGNC:6995]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04022//cGMP-PKG signaling pathway;ko04371//Apelin signaling pathway	K09261;K09261	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005829//cytosol;GO:0030054//cell junction	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0046983//protein dimerization activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048513//animal organ development"	SRF
ENSG00000214013	4.486	4.057	4.576	4.432	5.441	4.127	202.7	233.41	184.52	169.12	195.91	155.2	GANC	"glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K12317;K12317;K12317	-	"GO:0003824//catalytic activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0032450//maltose alpha-glucosidase activity;GO:0090599//alpha-glucosidase activity"	GO:0000023//maltose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006491//N-glycan processing;GO:0008152//metabolic process	--
ENSG00000214021	7.082	5.729	8.884	10.229	7.923	9.863	329.74	269.34	270.4	347.07	293.11	255.79	TTLL3	tubulin tyrosine ligase like 3 [Source:HGNC Symbol;Acc:HGNC:24483]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	"GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0070735//protein-glycine ligase activity;GO:0070736//protein-glycine ligase activity, initiating"	GO:0006464//cellular protein modification process;GO:0018094//protein polyglycylation;GO:0030317//flagellated sperm motility;GO:0035082//axoneme assembly;GO:0060271//cilium assembly	--
ENSG00000214022	59.882	55.866	64.538	68.519	64.957	71.796	3468	3308	2783	2969	3164	3061	REPIN1	replication initiator 1 [Source:HGNC Symbol;Acc:HGNC:17922]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043035//chromatin insulator sequence binding;GO:0046872//metal ion binding	GO:0006260//DNA replication;GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000214026	24.323	27.298	30.013	31.077	30.899	31.678	339	382	310	321	364	321	MRPL23	mitochondrial ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10322]	Genetic Information Processing	Translation	ko03010//Ribosome	K02892	GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000214029	0.701	0.269	0.506	0.366	0.295	0.227	135.58	97.15	58.85	61.57	53.96	58.54	ZNF891	zinc finger protein 891 [Source:HGNC Symbol;Acc:HGNC:38709]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000214042	0	0	0	0	0	0	0	0	0	0	0	0	IFNA7	interferon alpha 7 [Source:HGNC Symbol;Acc:HGNC:5428]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000214046	24.955	28.5	31.678	30.311	25.872	32.921	636	729	573	543	562.94	581.95	SMIM7	small integral membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:28419]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214050	2.991	3.575	2.94	2.661	2.029	2.838	72.02	84	42	50	41	43	FBXO16	F-box protein 16 [Source:HGNC Symbol;Acc:HGNC:13618]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000214063	43.94	50.59	60.972	75.437	67.634	61.193	1271	1517	1338	1644	1659	1293	TSPAN4	tetraspanin 4 [Source:HGNC Symbol;Acc:HGNC:11859]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0003823//antigen binding;GO:0005178//integrin binding;GO:0005515//protein binding	GO:0065003//protein-containing complex assembly	--
ENSG00000214078	36.03	39.594	46.237	44.405	38.255	41.442	1307.45	1415.8	1118	1133.35	1163.01	1057.76	CPNE1	copine 1 [Source:HGNC Symbol;Acc:HGNC:2314]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016235//aggresome;GO:0031965//nuclear membrane;GO:0035577//azurophil granule membrane;GO:0070062//extracellular exosome	GO:0001786//phosphatidylserine binding;GO:0004175//endopeptidase activity;GO:0005215//transporter activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding	GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0010629//negative regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043392//negative regulation of DNA binding;GO:0045666//positive regulation of neuron differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0071277//cellular response to calcium ion;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1990138//neuron projection extension	--
ENSG00000214087	14.647	13.79	13.876	13	13.254	13.957	296	276	216	199	224	202	ARL16	ADP ribosylation factor like GTPase 16 [Source:HGNC Symbol;Acc:HGNC:27902]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	-	--
ENSG00000214097	0	0	0	0	0	0	0	0	0	0	0	0	SMCO1	single-pass membrane protein with coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:27407]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000214102	0.016	0.094	0	0	0.094	0.022	1	6	0	0	1	1	WEE2	WEE2 oocyte meiosis inhibiting kinase [Source:HGNC Symbol;Acc:HGNC:19684]	Human Diseases;Cellular Processes	Infectious disease: viral;Cell growth and death	ko05170//Human immunodeficiency virus 1 infection;ko04110//Cell cycle	K06632;K06632	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007143//female meiotic nuclear division;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035038//female pronucleus assembly;GO:0042327//positive regulation of phosphorylation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0051321//meiotic cell cycle;GO:0060631//regulation of meiosis I;GO:0080154//regulation of fertilization;GO:1900194//negative regulation of oocyte maturation	--
ENSG00000214107	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB1	MAGE family member B1 [Source:HGNC Symbol;Acc:HGNC:6808]	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000214113	13.612	12.452	11.264	13.859	14.644	16.414	409	355	239	275	355	346	LYRM4	LYR motif containing 4 [Source:HGNC Symbol;Acc:HGNC:21365]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016604//nuclear body;GO:1990221//L-cysteine desulfurase complex;GO:1990229//iron-sulfur cluster assembly complex	GO:0005515//protein binding	GO:0016226//iron-sulfur cluster assembly	--
ENSG00000214114	5.786	5.096	4.624	4.192	4.317	3.585	279	251	137	163	166	137	MYCBP	MYC binding protein [Source:HGNC Symbol;Acc:HGNC:7554]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000214128	0	0	0	0	0	0	0	0	0	0	0	0	TMEM213	transmembrane protein 213 [Source:HGNC Symbol;Acc:HGNC:27220]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214140	0	0.024	0	0.098	0.057	0.133	0	1	0	3	2	4	PRCD	photoreceptor disc component [Source:HGNC Symbol;Acc:HGNC:32528]	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0042622//photoreceptor outer segment membrane;GO:0042995//cell projection	-	GO:0007601//visual perception;GO:0050896//response to stimulus	--
ENSG00000214160	28.559	32.964	32.355	40.944	35.347	38.883	870	984	708	894	871	857	ALG3	"ALG3 alpha-1,3- mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23056]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03845;K03845;K03845	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000030//mannosyltransferase activity;GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0052925//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0097502//mannosylation	--
ENSG00000214193	1.29	1.398	0.612	0.717	0.801	1.099	86.42	87.62	27.26	40.22	48.15	43.29	SH3D21	SH3 domain containing 21 [Source:HGNC Symbol;Acc:HGNC:26236]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0007015//actin filament organization;GO:0016477//cell migration	--
ENSG00000214194	37.021	37.89	38.078	37.233	29.792	35.489	774	795	584	572	524	539	SMIM30	small integral membrane protein 30 [Source:HGNC Symbol;Acc:HGNC:48953]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214212	0.091	0.181	0.237	0.161	0.108	0	2	4	4	3	2	0	C19orf38	chromosome 19 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:34073]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000214216	0	0	0	0	0	0	0	0	0	0	0	0	IQCJ	IQ motif containing J [Source:HGNC Symbol;Acc:HGNC:32406]	-	-	-	-	-	-	-	--
ENSG00000214226	0.308	0.283	0.224	0.128	0.392	0.293	13	12	7	4	14	9	C17orf67	chromosome 17 open reading frame 67 [Source:HGNC Symbol;Acc:HGNC:27900]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000214237	0	0.047	0	0	0	0	0	2	0	0	0	0	MINDY4B	MINDY family member 4B [Source:HGNC Symbol;Acc:HGNC:35475]	-	-	-	-	-	GO:0004843//thiol-dependent deubiquitinase;GO:1990380//Lys48-specific deubiquitinase activity	GO:0071108//protein K48-linked deubiquitination	--
ENSG00000214253	94.461	94.306	108.923	116.105	101.603	114.756	1701	1709	1447	1547	1547	1498	FIS1	"fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689]"	Cellular Processes	Transport and catabolism	ko04137//Mitophagy - animal	K17969	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000266//mitochondrial fission;GO:0000422//autophagy of mitochondrion;GO:0001836//release of cytochrome c from mitochondria;GO:0006626//protein targeting to mitochondrion;GO:0006915//apoptotic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008053//mitochondrial fusion;GO:0010821//regulation of mitochondrion organization;GO:0016559//peroxisome fission;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0070584//mitochondrion morphogenesis;GO:0090141//positive regulation of mitochondrial fission;GO:0090314//positive regulation of protein targeting to membrane;GO:1903579//negative regulation of ATP metabolic process;GO:2000192//negative regulation of fatty acid transport;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway	--
ENSG00000214265	0.811	0.734	0.598	0.942	0.348	0.202	22.3	20.27	12.13	19.17	8.09	4.04	SNURF	novel protein	-	-	-	-	GO:0016607//nuclear speck	-	-	--
ENSG00000214274	7.549	8.14	7.647	7.049	7.547	10.915	191.34	207.39	143.15	132.34	161.61	201.29	ANG	angiogenin [Source:HGNC Symbol;Acc:HGNC:483]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K16631	GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030426//growth cone;GO:0031410//cytoplasmic vesicle;GO:0032311//angiogenin-PRI complex;GO:0043025//neuronal cell body	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003779//actin binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0004540//ribonuclease activity;GO:0005102//signaling receptor binding;GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016787//hydrolase activity;GO:0019843//rRNA binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity	"GO:0001525//angiogenesis;GO:0001541//ovarian follicle development;GO:0001556//oocyte maturation;GO:0001666//response to hypoxia;GO:0001890//placenta development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006651//diacylglycerol biosynthetic process;GO:0007154//cell communication;GO:0007202//activation of phospholipase C activity;GO:0009303//rRNA transcription;GO:0009725//response to hormone;GO:0016070//RNA metabolic process;GO:0016078//tRNA catabolic process;GO:0016477//cell migration;GO:0017148//negative regulation of translation;GO:0019731//antibacterial humoral response;GO:0030041//actin filament polymerization;GO:0030154//cell differentiation;GO:0032148//activation of protein kinase B activity;GO:0032431//activation of phospholipase A2 activity;GO:0042327//positive regulation of phosphorylation;GO:0042592//homeostatic process;GO:0045087//innate immune response;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0050714//positive regulation of protein secretion;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000214279	0.011	0.022	0.045	0	0.066	0.015	1	2	3	0	5	1	SCART1	scavenger receptor family member expressed on T cells 1 [Source:HGNC Symbol;Acc:HGNC:32411]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005044//scavenger receptor activity	GO:0002376//immune system process;GO:0002456//T cell mediated immunity;GO:0006897//endocytosis;GO:0008150//biological_process	--
ENSG00000214285	0	0	0	0	0	0	0	0	0	0	0	0	NPS	neuropeptide S [Source:HGNC Symbol;Acc:HGNC:33940]	-	-	-	-	GO:0005576//extracellular region	-	"GO:0007218//neuropeptide signaling pathway;GO:0008542//visual learning;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0045760//positive regulation of action potential;GO:0051968//positive regulation of synaptic transmission, glutamatergic"	--
ENSG00000214290	0.089	0.367	0.277	0.281	0.244	0.307	2	9	6	5	5	5	COLCA2	colorectal cancer associated 2 [Source:HGNC Symbol;Acc:HGNC:26978]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000214300	0.045	0.045	0	0.082	0	0	3	3	0	4	0	0	SPDYE3	speedy/RINGO cell cycle regulator family member E3 [Source:HGNC Symbol;Acc:HGNC:35462]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000214309	1.219	1.587	1.737	1.381	1.743	1.081	31	34	29	25	33	20	MBLAC1	metallo-beta-lactamase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22180]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004521//endoribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle"	--
ENSG00000214324	0	0	0	0	0	0	0	0	0	0	0	0	C3orf56	chromosome 3 open reading frame 56 [Source:HGNC Symbol;Acc:HGNC:32481]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000214336	0.373	0.456	0.46	0.893	0.763	0.466	22	27	20	39	38	20	FOXI3	forkhead box I3 [Source:HGNC Symbol;Acc:HGNC:35123]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000214338	0.013	0.09	0.017	0.112	0	0.071	1	7.64	1	7	0	4	SOGA3	SOGA family member 3 [Source:HGNC Symbol;Acc:HGNC:21494]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0010506//regulation of autophagy	--
ENSG00000214357	0.491	0.196	0.163	0.365	0.284	0.187	58	24	16	36	32	18	NEURL1B	neuralized E3 ubiquitin protein ligase 1B [Source:HGNC Symbol;Acc:HGNC:35422]	-	-	-	-	GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination;GO:0070086//ubiquitin-dependent endocytosis	--
ENSG00000214360	0	0	0	0	0	0	0	0	0	0	0	0	EFCAB9	EF-hand calcium binding domain 9 [Source:HGNC Symbol;Acc:HGNC:34530]	-	-	-	-	GO:0005737//cytoplasm;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0061891//calcium ion sensor activity	GO:0007283//spermatogenesis;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation	--
ENSG00000214367	1.883	1.672	2.661	1.095	1.662	1.991	173	145.5	113.8	71	120.09	100.95	HAUS3	HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0072686//mitotic spindle;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000214376	0	0.094	0.359	0	0.037	0.022	0	6	3	0	2	1	VSTM5	V-set and transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:34443]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection	-	GO:0021517//ventral spinal cord development;GO:0046847//filopodium assembly;GO:0051260//protein homooligomerization;GO:1904891//positive regulation of excitatory synapse assembly	--
ENSG00000214402	0.551	0.914	1.387	1.134	1.492	2.057	21	35	39	32	48	57	LCNL1	lipocalin like 1 [Source:HGNC Symbol;Acc:HGNC:34436]	-	-	-	-	-	GO:0036094//small molecule binding	-	--
ENSG00000214413	4.876	5.913	6.433	6.052	6.044	6.715	157.76	172.63	127.35	109.51	119.12	137.8	BBIP1	BBSome interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:28093]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005929//cilium;GO:0034464//BBSome;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0005515//protein binding	GO:0015031//protein transport;GO:0030030//cell projection organization;GO:0042755//eating behavior;GO:0060271//cilium assembly;GO:0097500//receptor localization to non-motile cilium	--
ENSG00000214414	0	0	0	0	0	0	0	0	0	0	0	0	TRIM77	tripartite motif containing 77 [Source:HGNC Symbol;Acc:HGNC:34228]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000214415	0	0	0	0	0	0	0	0	0	0	0	0	GNAT3	G protein subunit alpha transducin 3 [Source:HGNC Symbol;Acc:HGNC:22800]	Organismal Systems;Organismal Systems	Sensory system;Digestive system	ko04742//Taste transduction;ko04973//Carbohydrate digestion and absorption	K19729;K19729	GO:0001669//acrosomal vesicle;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0005930//axoneme;GO:0016324//apical plasma membrane;GO:0032991//protein-containing complex	GO:0000166//nucleotide binding;GO:0001664//G protein-coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019001//guanyl nucleotide binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0035094//response to nicotine;GO:0050909//sensory perception of taste;GO:0050913//sensory perception of bitter taste;GO:0050916//sensory perception of sweet taste;GO:0050917//sensory perception of umami taste	--
ENSG00000214435	5.234	5.775	4.719	3.825	4.029	3.949	266	295	177.12	144	173	146	AS3MT	arsenite methyltransferase [Source:HGNC Symbol;Acc:HGNC:17452]	Human Diseases	Cancer: overview	ko05208//Chemical carcinogenesis - reactive oxygen species	K07755	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0008168//methyltransferase activity;GO:0016740//transferase activity;GO:0030791//arsenite methyltransferase activity;GO:0030792//methylarsonite methyltransferase activity	GO:0009404//toxin metabolic process;GO:0018872//arsonoacetate metabolic process;GO:0032259//methylation	--
ENSG00000214447	1.337	0.228	1.193	1.75	1.699	0	94.22	16.18	62.08	91.32	101.15	0	FAM187A	family with sequence similarity 187 member A [Source:HGNC Symbol;Acc:HGNC:35153]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214456	0.351	0.388	0.167	0.662	0.192	0.241	18	20	6	16.56	8	9	PLIN5	perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196]	Organismal Systems	Endocrine system	ko03320//PPAR signaling pathway	K20255	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0035473//lipase binding;GO:0042802//identical protein binding	GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010884//positive regulation of lipid storage;GO:0010890//positive regulation of sequestering of triglyceride;GO:0010897//negative regulation of triglyceride catabolic process;GO:0019915//lipid storage;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0034389//lipid droplet organization;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0050995//negative regulation of lipid catabolic process;GO:0051646//mitochondrion localization;GO:0060192//negative regulation of lipase activity;GO:0060193//positive regulation of lipase activity;GO:2000378//negative regulation of reactive oxygen species metabolic process	--
ENSG00000214491	0.513	0.506	0.413	0.456	0.516	0.537	33	35	21	22	30	26	SEC14L6	SEC14 like lipid binding 6 [Source:HGNC Symbol;Acc:HGNC:40047]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000214510	0	0	0	0	0	0	0	0	0	0	0	0	SPINK13	serine peptidase inhibitor Kazal type 13 [Source:HGNC Symbol;Acc:HGNC:27200]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:1902225//negative regulation of acrosome reaction	--
ENSG00000214511	0	0	0	0	0.154	0	0	0	0	0	1	0	HIGD1C	HIG1 hypoxia inducible domain family member 1C [Source:HGNC Symbol;Acc:HGNC:28044]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0097250//mitochondrial respirasome assembly	--
ENSG00000214513	0	0	0	0	0	0	0	0	0	0	0	0	NOTO	notochord homeobox [Source:HGNC Symbol;Acc:HGNC:31839]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0001947//heart looping;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007368//determination of left/right symmetry;GO:0007417//central nervous system development;GO:0009880//embryonic pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0030182//neuron differentiation;GO:0030903//notochord development;GO:0044458//motile cilium assembly;GO:1902017//regulation of cilium assembly	Homeobox
ENSG00000214517	18.978	18.071	18.137	17.822	17.071	17.185	979	937	691	681	744	645	PPME1	protein phosphatase methylesterase 1 [Source:HGNC Symbol;Acc:HGNC:30178]	-	-	-	-	GO:0005654//nucleoplasm	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0019888//protein phosphatase regulator activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0045296//cadherin binding;GO:0051721//protein phosphatase 2A binding;GO:0051722//protein C-terminal methylesterase activity;GO:0051723//protein methylesterase activity;GO:0052689//carboxylic ester hydrolase activity	GO:0000086//G2/M transition of mitotic cell cycle;GO:0006482//protein demethylation;GO:0043086//negative regulation of catalytic activity;GO:0050790//regulation of catalytic activity	--
ENSG00000214518	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP2-2	keratin associated protein 2-2 [Source:HGNC Symbol;Acc:HGNC:18905]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000214530	17.744	17.879	20.311	19.974	16.964	20.996	587	610	491	483	496	522	STARD10	StAR related lipid transfer domain containing 10 [Source:HGNC Symbol;Acc:HGNC:10666]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005902//microvillus;GO:0005929//cilium;GO:0016020//membrane;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0046581//intercellular canaliculus	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006869//lipid transport	--
ENSG00000214562	2.467	3.485	2.721	2.588	3.193	2.289	137.18	194.5	101.99	114.96	133.03	95.57	NUTM2D	NUT family member 2D [Source:HGNC Symbol;Acc:HGNC:23447]	-	-	-	-	-	-	-	--
ENSG00000214575	4.156	3.106	4.866	4.946	3.999	5.145	219.45	181	161.32	198.29	203.01	207	CPEB1	cytoplasmic polyadenylation element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21744]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K02602;K02602	GO:0000932//P-body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0045202//synapse;GO:1990124//messenger ribonucleoprotein complex	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0043022//ribosome binding;GO:0045182//translation regulator activity;GO:0046872//metal ion binding"	GO:0006397//mRNA processing;GO:0006412//translation;GO:0006417//regulation of translation;GO:0032869//cellular response to insulin stimulus;GO:0071230//cellular response to amino acid stimulus;GO:0071456//cellular response to hypoxia;GO:1900365//positive regulation of mRNA polyadenylation;GO:2000766//negative regulation of cytoplasmic translation	Others
ENSG00000214595	0.876	0.604	0.473	0.494	0.609	0.503	154	107	62	64	90	64	EML6	EMAP like 6 [Source:HGNC Symbol;Acc:HGNC:35412]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding;GO:0008017//microtubule binding	-	--
ENSG00000214642	0	0	0	0	0	0	0	0	0	0	0	0	DEFB113	defensin beta 113 [Source:HGNC Symbol;Acc:HGNC:18094]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000214652	0	0	0	0	0	0	0	0	0	0	0	0	ZNF727	zinc finger protein 727 [Source:HGNC Symbol;Acc:HGNC:22785]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000214654	1.143	1.781	1.348	1.567	1.129	0.779	85	118	74	61	71	42	B3GALT9	"beta-1,3-galactosyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:53652]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0006486//protein glycosylation	--
ENSG00000214655	19.708	20.697	23.46	21.188	23.87	25.786	2125.45	2280.09	1927.6	1783.73	2163.19	2004.52	ZSWIM8	zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:2000627//positive regulation of miRNA catabolic process	--
ENSG00000214681	0	0	0	0	0	0	0	0	0	0	0	0	IQCF5	IQ motif containing F5 [Source:HGNC Symbol;Acc:HGNC:35159]	-	-	-	-	-	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000214686	0	0	0	0	0	0	0	0	0	0	0	0	IQCF6	IQ motif containing F6 [Source:HGNC Symbol;Acc:HGNC:35158]	-	-	-	-	-	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000214688	0	0	0.055	0	0	0	0	0	4	0	0	0	C10orf105	chromosome 10 open reading frame 105 [Source:HGNC Symbol;Acc:HGNC:20304]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214694	0.056	0.104	0.061	0.076	0.04	0.154	5	9.79	4	5	3	10	ARHGEF33	Rho guanine nucleotide exchange factor 33 [Source:HGNC Symbol;Acc:HGNC:37252]	-	-	-	-	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000214700	0	0	0	0	0	0	0	0	0	0	0	0	C12orf71	chromosome 12 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:34452]	-	-	-	-	-	-	-	--
ENSG00000214706	21.769	21.167	23.446	24.491	25.185	23.8	871	854	694	727	855	691	IFRD2	interferon related developmental regulator 2 [Source:HGNC Symbol;Acc:HGNC:5457]	-	-	-	-	GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	-	--
ENSG00000214711	0.153	0.038	0.103	0.103	0.06	0.14	12	3	6	6	4	8	CAPN14	calpain 14 [Source:HGNC Symbol;Acc:HGNC:16664]	-	-	-	-	GO:0005737//cytoplasm	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000214717	10.326	10.238	8.937	9.914	11.642	10.42	854.34	886.08	616	622	760	600	ZBED1	zinc finger BED-type containing 1 [Source:HGNC Symbol;Acc:HGNC:447]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0016605//PML body;GO:0031965//nuclear membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0019789//SUMO transferase activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0061665//SUMO ligase activity;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0016925//protein sumoylation;GO:0044828//negative regulation by host of viral genome replication;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1990466//protein autosumoylation"	zf-BED
ENSG00000214736	57.501	61.684	67.75	66.421	53.822	58.633	713.35	768.8	619.23	608.53	561.42	526.84	TOMM6	translocase of outer mitochondrial membrane 6 [Source:HGNC Symbol;Acc:HGNC:34528]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0016020//membrane	GO:0005515//protein binding	GO:0015031//protein transport;GO:0045040//protein insertion into mitochondrial outer membrane	--
ENSG00000214753	16.934	18.021	17.806	16.39	17.229	15.671	1831.44	1958.94	1422.24	1312.98	1574.18	1233.17	HNRNPUL2	heterogeneous nuclear ribonucleoprotein U like 2 [Source:HGNC Symbol;Acc:HGNC:25451]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000214756	1.256	1.344	1.123	1.31	1.038	2.183	53	57	35	40.94	37	67	CSKMT	citrate synthase lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:33113]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0006479//protein methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0032259//methylation	--
ENSG00000214782	0	0	0	0	0	0	0	0	0	0	0	0	MS4A18	membrane spanning 4-domains A18 [Source:HGNC Symbol;Acc:HGNC:37636]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007166//cell surface receptor signaling pathway	--
ENSG00000214787	0.397	0.179	0.384	0.432	0.78	0.504	20.29	9.22	14.5	16.36	33.68	18.75	MS4A4E	membrane spanning 4-domains A4E [Source:HGNC Symbol;Acc:HGNC:14284]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214814	0	0	0	0	0	0	0	0	0	0	0	0	FER1L6	fer-1 like family member 6 [Source:HGNC Symbol;Acc:HGNC:28065]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding	GO:0007009//plasma membrane organization;GO:0009617//response to bacterium	--
ENSG00000214819	0	0	0	0	0	0	0	0	0	0	0	0	CDRT15L2	CMT1A duplicated region transcript 15 like 2 [Source:HGNC Symbol;Acc:HGNC:34075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000214827	0.266	0.073	0.423	0.258	0.224	0.261	12.04	3.34	14.16	8.65	8.59	8.59	MTCP1	mature T cell proliferation 1 [Source:HGNC Symbol;Acc:HGNC:7423]	Environmental Information Processing	Signal transduction	ko04151//PI3K-Akt signaling pathway	K16837	GO:0032991//protein-containing complex	GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity	GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000214842	0	0	0	0.017	0	0	0	0	0	1	0	0	RAD51AP2	RAD51 associated protein 2 [Source:HGNC Symbol;Acc:HGNC:34417]	-	-	-	-	GO:0032991//protein-containing complex	GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0008150//biological_process;GO:0036297//interstrand cross-link repair	--
ENSG00000214860	0	0.073	0	0	0	0	0	3	0	0	0	0	EVPLL	envoplakin like [Source:HGNC Symbol;Acc:HGNC:35236]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0016020//membrane	GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding	GO:0008544//epidermis development;GO:0042060//wound healing;GO:0045104//intermediate filament cytoskeleton organization	--
ENSG00000214866	0	0	0	0	0	0	0	0	0	0	0	0	DCDC2C	doublecortin domain containing 2C [Source:HGNC Symbol;Acc:HGNC:32696]	-	-	-	-	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005929//cilium;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection	-	GO:0035556//intracellular signal transduction	--
ENSG00000214872	0.284	0.255	0.193	0.154	0.269	0.235	10	9	5	4	8	6	SMTNL1	smoothelin like 1 [Source:HGNC Symbol;Acc:HGNC:32394]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0030016//myofibril;GO:0031430//M band;GO:0031674//I band;GO:0031941//filamentous actin;GO:0043292//contractile fiber	GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005523//tropomyosin binding;GO:0008157//protein phosphatase 1 binding;GO:0043621//protein self-association;GO:0051401//CH domain binding;GO:0097718//disordered domain specific binding	"GO:0009410//response to xenobiotic stimulus;GO:0014823//response to activity;GO:0018105//peptidyl-serine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0042310//vasoconstriction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045907//positive regulation of vasoconstriction;GO:0048644//muscle organ morphogenesis"	--
ENSG00000214891	0	0	0	0	0	0	0	0	0	0	0	0	TRIM64C	tripartite motif containing 64C [Source:HGNC Symbol;Acc:HGNC:37148]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000214897	0	0	0	0	0	0	0	0	0	0	0	0	PNMA6E	PNMA family member 6E [Source:HGNC Symbol;Acc:HGNC:50767]	-	-	-	-	-	-	-	--
ENSG00000214929	0	0	0	0	0	0	0	0	0	0	0	0	SPATA31D1	SPATA31 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:37283]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000214940	0.469	0	0	0	0.184	0	11	0	0	0	1.26	0	NPIPA8	nuclear pore complex interacting protein family member A8 [Source:HGNC Symbol;Acc:HGNC:41983]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000214941	11.041	10.838	9.976	10.031	10.132	10.788	230	216	141	150	161	150	ZSWIM7	zinc finger SWIM-type containing 7 [Source:HGNC Symbol;Acc:HGNC:26993]	-	-	-	-	GO:0005634//nucleus;GO:0097196//Shu complex	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0050821//protein stabilization	--
ENSG00000214943	0	0	0	0	0	0	0	0	0	0	0	0	GPR33	G protein-coupled receptor 33 [Source:HGNC Symbol;Acc:HGNC:4489]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004875//complement receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0002430//complement receptor mediated signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration	--
ENSG00000214944	2.122	1.818	1.193	1.697	2.24	2.149	254	210	99	133	207	185	ARHGEF28	Rho guanine nucleotide exchange factor 28 [Source:HGNC Symbol;Acc:HGNC:30322]	Human Diseases	Infectious disease: bacterial	ko05135//Yersinia infection	K21072	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0000902//cell morphogenesis;GO:0030154//cell differentiation;GO:0035023//regulation of Rho protein signal transduction;GO:0048013//ephrin receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000214946	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D26	TBC1 domain family member 26 [Source:HGNC Symbol;Acc:HGNC:28745]	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000214954	0.475	0.33	0.504	0.362	0.76	0.184	8	7	6	4	10	2	LRRC69	leucine rich repeat containing 69 [Source:HGNC Symbol;Acc:HGNC:34303]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000214960	11.367	8.765	10.375	9.371	9.407	13.359	813	622	523	463	539	707	CRPPA	CDP-L-ribitol pyrophosphorylase A [Source:HGNC Symbol;Acc:HGNC:37276]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00040//Pentose and glucuronate interconversions;ko00515//Mannose type O-glycan biosynthesis	K21031;K21031;K21031	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0042803//protein homodimerization activity;GO:0047349//D-ribitol-5-phosphate cytidylyltransferase activity;GO:0070567//cytidylyltransferase activity	GO:0006486//protein glycosylation;GO:0007411//axon guidance;GO:0008299//isoprenoid biosynthetic process;GO:0035269//protein O-linked mannosylation	--
ENSG00000214967	1.294	1.748	1.969	2.603	3.163	3.15	15.06	20.45	16.92	24.03	31.1	26.67	NPIPA7	nuclear pore complex interacting protein family member A7 [Source:HGNC Symbol;Acc:HGNC:41982]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000214978	0	0	0	0	0	0	0	0	0	0	0	0	GSG1L2	GSG1 like 2 [Source:HGNC Symbol;Acc:HGNC:51826]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000215009	0	0	0	0	0	0	0	0	0	0	0	0	ACSM4	acyl-CoA synthetase medium chain family member 4 [Source:HGNC Symbol;Acc:HGNC:32016]	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00650//Butanoate metabolism	K01896;K01896	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0005524//ATP binding;GO:0015645//fatty acid ligase activity;GO:0016874//ligase activity;GO:0031956//medium-chain fatty acid-CoA ligase activity;GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0102391//decanoate-CoA ligase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006637//acyl-CoA metabolic process	--
ENSG00000215012	4.026	5.03	4.576	4.277	5.201	4.377	551.01	619.26	464.02	434.55	494	442.64	RTL10	retrotransposon Gag like 10 [Source:HGNC Symbol;Acc:HGNC:26112]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0006915//apoptotic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0097345//mitochondrial outer membrane permeabilization	--
ENSG00000215018	0.045	0.069	0.03	0.03	0.166	0.076	4	1	2	2	2	4	COL28A1	collagen type XXVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22442]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K23619	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent;GO:0030020//extracellular matrix structural constituent conferring tensile strength;GO:0030414//peptidase inhibitor activity	GO:0007155//cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0030198//extracellular matrix organization	--
ENSG00000215021	113.364	118.721	115.015	126.61	119.739	112.721	3225	3391	2411	2674	2882	2335	PHB2	prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016363//nuclear matrix;GO:0030424//axon;GO:0032991//protein-containing complex;GO:0035632//mitochondrial prohibitin complex;GO:0048786//presynaptic active zone;GO:0071944//cell periphery;GO:0098800//inner mitochondrial membrane protein complex;GO:0098978//glutamatergic synapse;GO:0098982//GABA-ergic synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0030331//estrogen receptor binding;GO:0033218//amide binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046625//sphingolipid binding;GO:0046982//protein heterodimerization activity;GO:0047485//protein N-terminus binding	"GO:0000423//mitophagy;GO:0002639//positive regulation of immunoglobulin production;GO:0006606//protein import into nucleus;GO:0007005//mitochondrion organization;GO:0007062//sister chromatid cohesion;GO:0007202//activation of phospholipase C activity;GO:0009611//response to wounding;GO:0016477//cell migration;GO:0023035//CD40 signaling pathway;GO:0031536//positive regulation of exit from mitosis;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0039529//RIG-I signaling pathway;GO:0042113//B cell activation;GO:0043066//negative regulation of apoptotic process;GO:0043433//negative regulation of DNA-binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050821//protein stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0060744//mammary gland branching involved in thelarche;GO:0060749//mammary gland alveolus development;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071300//cellular response to retinoic acid;GO:0071456//cellular response to hypoxia;GO:0140374//antiviral innate immune response;GO:1900208//regulation of cardiolipin metabolic process;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:1904959//regulation of cytochrome-c oxidase activity;GO:1990051//activation of protein kinase C activity"	--
ENSG00000215029	0	0	0	0	0	0	0	0	0	0	0	0	TCP11X2	"t-complex 11 family, X-linked 2 [Source:HGNC Symbol;Acc:HGNC:48335]"	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0036126//sperm flagellum	-	GO:0007165//signal transduction;GO:0010737//protein kinase A signaling;GO:1902490//regulation of sperm capacitation	--
ENSG00000215041	5.367	5.999	7.658	6.285	7.543	7.304	565.32	650.44	569.43	494.48	632	551.59	NEURL4	neuralized E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:34410]	-	-	-	-	GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000215045	0.03	0.015	0.041	0.019	0	0.103	2	1	2	1	0	5	GRID2IP	Grid2 interacting protein [Source:HGNC Symbol;Acc:HGNC:18464]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane	GO:0005515//protein binding	GO:0060292//long-term synaptic depression	--
ENSG00000215113	0	0	0	0	0	0	0	0	0	0	0	0	CXorf49B	chromosome X open reading frame 49B [Source:HGNC Symbol;Acc:HGNC:34229]	-	-	-	-	-	-	-	--
ENSG00000215114	11.075	8.921	10.771	8.09	7.555	11.06	998	781	647	469	620	694	UBXN2B	UBX domain protein 2B [Source:HGNC Symbol;Acc:HGNC:27035]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031616//spindle pole centrosome	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0000045//autophagosome assembly;GO:0000132//establishment of mitotic spindle orientation;GO:0007030//Golgi organization;GO:0031468//nuclear membrane reassembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0046604//positive regulation of mitotic centrosome separation;GO:0061025//membrane fusion;GO:1904780//negative regulation of protein localization to centrosome	--
ENSG00000215115	0	0	0	0	0	0	0	0	0	0	0	0	CXorf49	chromosome X open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:30891]	-	-	-	-	-	-	-	--
ENSG00000215126	0.159	0.244	3.222	4.625	0.458	0.359	5.61	9.25	42.5	56.84	16.67	9.76	CBWD6	COBW domain containing 6 [Source:HGNC Symbol;Acc:HGNC:31978]	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000215131	0	0	0	0	0	0.143	0	0	0	0	0	2	C16orf90	chromosome 16 open reading frame 90 [Source:HGNC Symbol;Acc:HGNC:34455]	-	-	-	-	-	-	-	--
ENSG00000215148	0	0	0	0	0	0	0	0	0	0	0	0	PRSS41	serine protease 41 [Source:HGNC Symbol;Acc:HGNC:30715]	-	-	-	-	-	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000215174	0	0.03	0	0	0	0	0	2	0	0	0	0	NLRP2B	NLR family pyrin domain containing 2B [Source:HGNC Symbol;Acc:HGNC:29887]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	GO:0002376//immune system process;GO:0009968//negative regulation of signal transduction;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0045087//innate immune response;GO:0045786//negative regulation of cell cycle	--
ENSG00000215182	0.003	0	0	0	0	0	1	0	0	0	0	0	MUC5AC	"mucin 5AC, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7515]"	Organismal Systems	Immune system	ko04657//IL-17 signaling pathway	K21125	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0070701//mucus layer	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding	GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000215183	0.08	0	0	0	0	0	1.12	0	0	0	0	0	MSMP	"microseminoprotein, prostate associated [Source:HGNC Symbol;Acc:HGNC:29663]"	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005125//cytokine activity;GO:0031727//CCR2 chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0048247//lymphocyte chemotaxis	--
ENSG00000215186	0	0	0	0.024	0	0	0	0	0	2	0	0	GOLGA6B	golgin A6 family member B [Source:HGNC Symbol;Acc:HGNC:32205]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	-	GO:0007030//Golgi organization	--
ENSG00000215187	0.183	0.835	0.495	0.989	0.232	0.351	4	18	8	15	4	5	FAM166B	family with sequence similarity 166 member B [Source:HGNC Symbol;Acc:HGNC:34242]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000215193	6.696	5.358	6.007	7.595	7.898	7.283	1055.67	1049.27	782.46	831.68	910.44	735.29	PEX26	peroxisomal biogenesis factor 26 [Source:HGNC Symbol;Acc:HGNC:22965]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13340	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0044877//protein-containing complex binding;GO:0051117//ATPase binding	GO:0015031//protein transport;GO:0016558//protein import into peroxisome matrix;GO:0045046//protein import into peroxisome membrane	--
ENSG00000215203	0	0	0	0	0	0	0	0	0	0	0	0	GRXCR1	glutaredoxin and cysteine rich domain containing 1 [Source:HGNC Symbol;Acc:HGNC:31673]	-	-	-	-	GO:0005902//microvillus;GO:0005929//cilium;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0060091//kinocilium	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0097573//glutathione oxidoreductase activity	GO:0007605//sensory perception of sound;GO:0042491//inner ear auditory receptor cell differentiation;GO:0048563//post-embryonic animal organ morphogenesis;GO:0048839//inner ear development;GO:0060118//vestibular receptor cell development;GO:0060119//inner ear receptor cell development;GO:0060122//inner ear receptor cell stereocilium organization	--
ENSG00000215217	4.643	4.229	4.232	2.72	2.193	2.739	137	138	80	70	66	61	C5orf49	chromosome 5 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:27028]	-	-	-	-	GO:0036064//ciliary basal body	GO:0005515//protein binding	-	--
ENSG00000215218	0.311	0.195	0.21	0.342	0.465	0.259	38	24	19	31	48	23	UBE2QL1	ubiquitin conjugating enzyme E2 Q family like 1 [Source:HGNC Symbol;Acc:HGNC:37269]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10582	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0016567//protein ubiquitination	--
ENSG00000215251	7.328	7.223	7.304	8.245	6.767	7.908	432	428	318	360	337	341	FASTKD5	FAST kinase domains 5 [Source:HGNC Symbol;Acc:HGNC:25790]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0035770//ribonucleoprotein granule;GO:0042645//mitochondrial nucleoid	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0000963//mitochondrial RNA processing;GO:0006397//mRNA processing;GO:0044528//regulation of mitochondrial mRNA stability	--
ENSG00000215252	1.077	1.247	1.164	1.561	1.856	1.384	98.99	114.88	77.81	103.36	138.29	89.13	GOLGA8B	golgin A8 family member B [Source:HGNC Symbol;Acc:HGNC:31973]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization;GO:0051225//spindle assembly	--
ENSG00000215262	0	0	0.018	0	0	0	0	0	1	0	0	0	KCNU1	potassium calcium-activated channel subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:18867]	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K05274;K05274;K05274	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0022414//reproductive process;GO:0034220//ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000215269	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12G	G antigen 12G [Source:HGNC Symbol;Acc:HGNC:31907]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000215271	6.837	5.22	4.955	8.157	6.413	6.902	396	339	257	311	343	319	HOMEZ	homeobox and leucine zipper encoding [Source:HGNC Symbol;Acc:HGNC:20164]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000215274	0	0	0	0	0	0	0	0	0	0	0	0	GAGE10	G antigen 10 [Source:HGNC Symbol;Acc:HGNC:30968]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000215277	0	0	0	0	0	0	0	0	0	0	0	0	RNF212B	ring finger protein 212B [Source:HGNC Symbol;Acc:HGNC:20438]	-	-	-	-	GO:0000795//synaptonemal complex	GO:0019789//SUMO transferase activity;GO:0046872//metal ion binding	GO:0007129//homologous chromosome pairing at meiosis;GO:0007131//reciprocal meiotic recombination;GO:0016925//protein sumoylation	--
ENSG00000215301	85.294	75.18	80.56	64.987	72.673	87.454	7997	7071	5634	4578	5560	6030	DDX3X	DEAD-box helicase 3 X-linked [Source:HGNC Symbol;Acc:HGNC:2745]	Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Infectious disease: viral;Immune system	ko05203//Viral carcinogenesis;ko05161//Hepatitis B;ko04622//RIG-I-like receptor signaling pathway	K11594;K11594;K11594	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0010494//cytoplasmic stress granule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0030027//lamellipodium;GO:0031252//cell leading edge;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0043186//P granule;GO:0061702//inflammasome complex;GO:0070062//extracellular exosome;GO:0072559//NLRP3 inflammasome complex;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0003729//mRNA binding;GO:0003924//GTPase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008134//transcription factor binding;GO:0008143//poly(A) binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0017111//nucleoside-triphosphatase activity;GO:0031369//translation initiation factor binding;GO:0033592//RNA strand annealing activity;GO:0035613//RNA stem-loop binding;GO:0043015//gamma-tubulin binding;GO:0043024//ribosomal small subunit binding;GO:0043273//CTPase activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0045296//cadherin binding;GO:0048027//mRNA 5'-UTR binding	GO:0002376//immune system process;GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0006915//apoptotic process;GO:0007059//chromosome segregation;GO:0007276//gamete generation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0009615//response to virus;GO:0010501//RNA secondary structure unwinding;GO:0010628//positive regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:0017148//negative regulation of translation;GO:0030154//cell differentiation;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0031053//primary miRNA processing;GO:0031333//negative regulation of protein-containing complex assembly;GO:0031954//positive regulation of protein autophosphorylation;GO:0032508//DNA duplex unwinding;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0034063//stress granule assembly;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0034161//positive regulation of toll-like receptor 8 signaling pathway;GO:0035556//intracellular signal transduction;GO:0036493//positive regulation of translation in response to endoplasmic reticulum stress;GO:0042254//ribosome biogenesis;GO:0042256//mature ribosome assembly;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045070//positive regulation of viral genome replication;GO:0045087//innate immune response;GO:0045727//positive regulation of translation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045948//positive regulation of translational initiation;GO:0055088//lipid homeostasis;GO:0071243//cellular response to arsenic-containing substance;GO:0071470//cellular response to osmotic stress;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0098586//cellular response to virus;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901985//positive regulation of protein acetylation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1903608//protein localization to cytoplasmic stress granule;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000215305	10.688	11.676	11.654	11.982	11.693	10.128	588	649	474	483	542	411	VPS16	VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20180	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005776//autophagosome;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0030424//axon;GO:0030897//HOPS complex;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0033263//CORVET complex;GO:0043025//neuronal cell body;GO:0055037//recycling endosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	"GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0007033//vacuole organization;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly;GO:0042144//vacuole fusion, non-autophagic;GO:0097352//autophagosome maturation"	--
ENSG00000215343	0.026	0	0	0	0	0	2	0	0	0	0	0	ZNF705D	zinc finger protein 705D [Source:HGNC Symbol;Acc:HGNC:33202]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000215356	0	0	0	0	0	0	0	0	0	0	0	0	ZNF705B	zinc finger protein 705B [Source:HGNC Symbol;Acc:HGNC:32284]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000215372	0	0	0	0	0	0	0	0	0	0	0	0	ZNF705G	zinc finger protein 705G [Source:HGNC Symbol;Acc:HGNC:37134]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000215375	3.51	5.008	4.852	6.507	4.634	3.375	75	95	74	81	77	58	MYL5	myosin light chain 5 [Source:HGNC Symbol;Acc:HGNC:7586]	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility;Cellular community - eukaryotes;Development and regeneration;Immune system	ko05132//Salmonella infection;ko05131//Shigellosis;ko04810//Regulation of actin cytoskeleton;ko04510//Focal adhesion;ko04360//Axon guidance;ko04670//Leukocyte transendothelial migration	K12753;K12753;K12753;K12753;K12753;K12753	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0016459//myosin complex	GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle;GO:0046872//metal ion binding	GO:0006937//regulation of muscle contraction	--
ENSG00000215397	0	0	0	0	0	0	0	0	0	0	0	0	SCRT2	scratch family transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:15952]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0070888//E-box binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001222//regulation of neuron migration"	zf-C2H2
ENSG00000215421	2.407	1.819	2.038	1.849	1.913	1.88	403	306	248	229	266	229	ZNF407	zinc finger protein 407 [Source:HGNC Symbol;Acc:HGNC:19904]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0010468//regulation of gene expression;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000215440	9.239	10.637	10.662	10.58	10.814	10.846	389	458	357	339	409	346	NPEPL1	aminopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:16244]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity;GO:0030145//manganese ion binding;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis;GO:0019538//protein metabolic process	--
ENSG00000215454	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-4	keratin associated protein 10-4 [Source:HGNC Symbol;Acc:HGNC:20521]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000215455	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-1	keratin associated protein 10-1 [Source:HGNC Symbol;Acc:HGNC:22966]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	-	--
ENSG00000215472	27.959	26.153	26.785	29.179	22.242	29.327	830.01	785.17	590.86	645.58	561.27	635.94	RPL17-C18orf32	RPL17-C18orf32 readthrough [Source:HGNC Symbol;Acc:HGNC:44661]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02880;K02880	GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003735//structural constituent of ribosome	GO:0006412//translation	--
ENSG00000215474	0	0	0	0	0	0	0	0	0	0	0	0	SKOR2	SKI family transcriptional corepressor 2 [Source:HGNC Symbol;Acc:HGNC:32695]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046332//SMAD binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway"	--
ENSG00000215475	0.116	0.122	0.046	0.028	0.04	0.037	17	18	5	3	5	4	SIAH3	siah E3 ubiquitin protein ligase family member 3 [Source:HGNC Symbol;Acc:HGNC:30553]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007275//multicellular organism development;GO:0016567//protein ubiquitination;GO:0031647//regulation of protein stability;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1903215//negative regulation of protein targeting to mitochondrion	--
ENSG00000215529	0	0	0	0	0	0	0	0	0	0	0	0	EFCAB8	EF-hand calcium binding domain 8 [Source:HGNC Symbol;Acc:HGNC:34532]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0005515//protein binding	-	--
ENSG00000215545	0	0	0	0	0	0	0	0	0	0	0	0	DEFB116	defensin beta 116 [Source:HGNC Symbol;Acc:HGNC:18097]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000215547	0	0	0	0	0	0	0	0	0	0	0	0	DEFB115	defensin beta 115 [Source:HGNC Symbol;Acc:HGNC:18096]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0006952//defense response;GO:0042742//defense response to bacterium	--
ENSG00000215568	0	0	0	0	0	0	0	0	0	0	0	0	GAB4	GRB2 associated binding protein family member 4 [Source:HGNC Symbol;Acc:HGNC:18325]	-	-	-	-	-	-	-	--
ENSG00000215595	0.08	0.08	0	0.081	0.142	0.11	4	4	0	3	6	4	C20orf202	chromosome 20 open reading frame 202 [Source:HGNC Symbol;Acc:HGNC:37254]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000215612	1.308	1.927	2.009	2.954	1.518	1.728	52	77	59	87	51	50	HMX1	H6 family homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5017]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	Homeobox
ENSG00000215644	0.14	0.228	0.322	0.104	0.091	0.131	3	9	10	3	3	4	GCGR	glucagon receptor [Source:HGNC Symbol;Acc:HGNC:4192]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04922//Glucagon signaling pathway	K04583;K04583	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004967//glucagon receptor activity;GO:0008528//G protein-coupled peptide receptor activity;GO:0017046//peptide hormone binding;GO:0038023//signaling receptor activity	GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007584//response to nutrient;GO:0008217//regulation of blood pressure;GO:0009267//cellular response to starvation;GO:0009755//hormone-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0042593//glucose homeostasis;GO:0042594//response to starvation;GO:0070873//regulation of glycogen metabolic process;GO:0071377//cellular response to glucagon stimulus	--
ENSG00000215695	4.055	3.557	2.622	2.71	1.537	2.766	195.22	172.1	93.23	96.64	62.5	96.89	RSC1A1	regulator of solute carriers 1 [Source:HGNC Symbol;Acc:HGNC:10458]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030054//cell junction	GO:0005515//protein binding;GO:0019871//sodium channel inhibitor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0010829//negative regulation of glucose transmembrane transport;GO:0032243//negative regulation of nucleoside transport;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0045920//negative regulation of exocytosis;GO:0051051//negative regulation of transport;GO:1903077//negative regulation of protein localization to plasma membrane"	--
ENSG00000215704	0	0	0	0	0	0	0	0	0	0	0	0	CELA2B	chymotrypsin like elastase 2B [Source:HGNC Symbol;Acc:HGNC:29995]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01346;K01346	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000215712	3.513	2.781	3.758	1.988	2.377	3.085	252	239	198	112	180	188	TMEM242	transmembrane protein 242 [Source:HGNC Symbol;Acc:HGNC:17206]	-	-	-	-	GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly	--
ENSG00000215717	26.741	24.415	24.399	22.206	24.027	27.9	1536	1410	1035	945	1166	1166	TMEM167B	transmembrane protein 167B [Source:HGNC Symbol;Acc:HGNC:30187]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0045054//constitutive secretory pathway	--
ENSG00000215784	0	0	0	0	0	0	0	0	0	0	0	0	FAM72D	family with sequence similarity 72 member D [Source:HGNC Symbol;Acc:HGNC:33593]	-	-	-	-	GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000215788	0.517	0.938	0.893	1.353	1.39	0.37	20	29	16	28	42	9	TNFRSF25	TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05160	GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0097190//apoptotic signaling pathway	--
ENSG00000215817	0.051	0.061	0.028	0.014	0	0.042	5.07	6.06	2.01	1.01	0	3.02	ZC3H11B	zinc finger CCCH-type containing 11B [Source:HGNC Symbol;Acc:HGNC:25659]	-	-	-	-	-	GO:0003729//mRNA binding;GO:0046872//metal ion binding	GO:0016973//poly(A)+ mRNA export from nucleus	--
ENSG00000215845	24.245	26.941	29.371	26.809	24.964	26.006	276	312	245	227	241	217	TSTD1	thiosulfate sulfurtransferase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:35410]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0048471//perinuclear region of cytoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0050337//thiosulfate-thiol sulfurtransferase activity"	"GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase"	--
ENSG00000215853	0	0	0	0	0	0	0	0	0	0	0	0	RPTN	repetin [Source:HGNC Symbol;Acc:HGNC:26809]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005829//cytosol	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding	-	--
ENSG00000215883	3.858	3.917	4.148	3.698	3.805	3.33	392.24	369.92	305.81	252.67	341.38	287	CYB5RL	cytochrome b5 reductase like [Source:HGNC Symbol;Acc:HGNC:32220]	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane	"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0016491//oxidoreductase activity"	GO:0015701//bicarbonate transport	--
ENSG00000215906	0	0	0	0	0	0	0	0	0	0	0	0	LACTBL1	lactamase beta like 1 [Source:HGNC Symbol;Acc:HGNC:35445]	-	-	-	-	-	-	-	--
ENSG00000215910	0.026	0.03	0.04	0.035	0.061	0	1	1	1	1	2.01	0	C1orf167	chromosome 1 open reading frame 167 [Source:HGNC Symbol;Acc:HGNC:25262]	-	-	-	-	-	-	-	--
ENSG00000215912	0.016	0.016	0.067	0.111	0.052	0.045	3	3	9	15	8	6	TTC34	tetratricopeptide repeat domain 34 [Source:HGNC Symbol;Acc:HGNC:34297]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000215915	0	0.038	0	0	0	0	0	3.03	0	0	0	0	ATAD3C	ATPase family AAA domain containing 3C [Source:HGNC Symbol;Acc:HGNC:32151]	-	-	-	-	GO:0005739//mitochondrion	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007005//mitochondrion organization	--
ENSG00000216490	70.194	76.885	80.32	92.166	80.722	90.234	1322.3	1431.8	1095.73	1248.86	1274.84	1291.48	IFI30	IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398]	Organismal Systems	Immune system	ko04612//Antigen processing and presentation	K08059	GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005829//cytosol;GO:0030054//cell junction;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle	"GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"	GO:0002376//immune system process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0048147//negative regulation of fibroblast proliferation;GO:0050821//protein stabilization	--
ENSG00000216588	0	0	0	0	0	0	0	0	0	0	0	0	IGSF23	immunoglobulin superfamily member 23 [Source:HGNC Symbol;Acc:HGNC:40040]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000216649	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12E	G antigen 12E [Source:HGNC Symbol;Acc:HGNC:31905]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000216921	0.19	0.186	0.386	0.257	0.338	0.253	2	2	3	2	3	2	FAM240C	family with sequence similarity 240 member C [Source:HGNC Symbol;Acc:HGNC:54200]	-	-	-	-	-	-	-	--
ENSG00000216937	0.418	0.301	0.049	0.036	1.009	0.124	18	8	3	1	15	5	CCDC7	coiled-coil domain containing 7 [Source:HGNC Symbol;Acc:HGNC:26533]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000217128	4.729	3.819	2.784	2.798	3.136	4.076	642	523	278.86	281	361	404	FNIP1	folliculin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29418]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20400	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0042030//ATPase inhibitor activity;GO:0051087//chaperone binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002327//immature B cell differentiation;GO:0002904//positive regulation of B cell apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0009267//cellular response to starvation;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031929//TOR signaling;GO:0032007//negative regulation of TOR signaling;GO:0032008//positive regulation of TOR signaling;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000973//regulation of pro-B cell differentiation	--
ENSG00000217236	0	0	0	0	0	0	0	0	0	0	0	0	SP9	Sp9 transcription factor [Source:HGNC Symbol;Acc:HGNC:30690]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0030326//embryonic limb morphogenesis	zf-C2H2
ENSG00000217442	0	0.104	0	0	0	0	0	1	0	0	0	0	SYCE3	synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245]	-	-	-	-	GO:0000801//central element;GO:0005634//nucleus;GO:0005694//chromosome	GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0051301//cell division;GO:0051321//meiotic cell cycle	--
ENSG00000217555	5.996	7.039	6.326	6.644	7.344	5.493	69.93	80.99	57.9	58.95	74	46.88	CKLF	chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity	GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0032940//secretion by cell;GO:0048246//macrophage chemotaxis;GO:0048247//lymphocyte chemotaxis	--
ENSG00000217930	3.748	5.323	6.899	5.716	6.345	6.642	42.7	60.8	57	48	61.71	55.6	PAM16	presequence translocase associated motor 16 [Source:HGNC Symbol;Acc:HGNC:29679]	-	-	-	-	"GO:0001405//PAM complex, Tim23 associated import motor;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0032991//protein-containing complex"	GO:0005515//protein binding	GO:0001503//ossification;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix;GO:0032780//negative regulation of ATPase activity	--
ENSG00000218305	0	0	0	0	0.02	0	0	0	0	0	1	0	CDC14C	cell division cycle 14C [Source:HGNC Symbol;Acc:HGNC:22427]	Cellular Processes	Cell growth and death	ko04110//Cell cycle	K06639	GO:0000922//spindle pole;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005813//centrosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0072686//mitotic spindle	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0000226//microtubule cytoskeleton organization;GO:0006470//protein dephosphorylation;GO:0007096//regulation of exit from mitosis;GO:0016311//dephosphorylation;GO:0032467//positive regulation of cytokinesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060271//cilium assembly	--
ENSG00000218336	9.766	10.913	5.964	9.064	8.798	11.665	1289	1402	670	687	876	751	TENM3	teneurin transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:29944]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0050839//cell adhesion molecule binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007165//signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0030154//cell differentiation;GO:0048593//camera-type eye morphogenesis;GO:0048666//neuron development;GO:1903385//regulation of homophilic cell adhesion	--
ENSG00000218739	14.83	13.286	13.087	12.608	11.299	14.91	755	689	534	492	546	576	CEBPZOS	CEBPZ opposite strand [Source:HGNC Symbol;Acc:HGNC:49288]	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	-	--
ENSG00000218819	0	0	0	0	0	0	0	0	0	0	0	0	TDRD15	tudor domain containing 15 [Source:HGNC Symbol;Acc:HGNC:45037]	-	-	-	-	GO:0043186//P granule	-	GO:0030719//P granule organization;GO:0034587//piRNA metabolic process	--
ENSG00000218823	0	0	0	0	0	0	0	0	0	0	0	0	PAPOLB	poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K14376	GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation	--
ENSG00000218891	10.005	10.517	9.356	12.783	11.176	13.772	474	564	394	468	493	511	ZNF579	zinc finger protein 579 [Source:HGNC Symbol;Acc:HGNC:26646]	-	-	-	-	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000219073	0	0	0	0	0	0	0	0	0	0	0	0	CELA3B	chymotrypsin like elastase 3B [Source:HGNC Symbol;Acc:HGNC:15945]	Organismal Systems;Organismal Systems	Digestive system;Digestive system	ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01345;K01345	GO:0005615//extracellular space	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000219200	138.217	129.43	146.85	173.967	146.212	170.801	1756	1660	1388.99	1647	1595	1583	RNASEK	ribonuclease K [Source:HGNC Symbol;Acc:HGNC:33911]	-	-	-	-	"GO:0000139//Golgi membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005575//cellular_component;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033176//proton-transporting V-type ATPase complex"	GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0006898//receptor-mediated endocytosis;GO:0007035//vacuolar acidification;GO:0007042//lysosomal lumen acidification;GO:0019065//receptor-mediated endocytosis of virus by host cell;GO:0048388//endosomal lumen acidification;GO:0051452//intracellular pH reduction;GO:0061795//Golgi lumen acidification;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:1902600//proton transmembrane transport"	--
ENSG00000219435	0	0	0	0	0	0	0	0	0	0	0	0	CATSPERZ	catsper channel auxiliary subunit zeta [Source:HGNC Symbol;Acc:HGNC:19231]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0031514//motile cilium;GO:0036128//CatSper complex;GO:0042995//cell projection;GO:0097228//sperm principal piece	-	GO:0007140//male meiotic nuclear division;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation	--
ENSG00000219438	7.872	7.767	7.223	10.184	7.08	9.467	313	304	235	290	267	274	TAFA5	TAFA chemokine like family member 5 [Source:HGNC Symbol;Acc:HGNC:21592]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001664//G protein-coupled receptor binding;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0061044//negative regulation of vascular wound healing;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation;GO:1904753//negative regulation of vascular associated smooth muscle cell migration	--
ENSG00000219481	11.16	10.815	11.7	8.897	9.677	12.074	1304.49	1296.99	1036.52	780.11	965.19	1043.93	NBPF1	NBPF member 1 [Source:HGNC Symbol;Acc:HGNC:26088]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	-	--
ENSG00000219545	13.756	10.389	11.213	11.886	9.939	13.901	598	462	343	387	365	435	UMAD1	UBAP1-MVB12-associated (UMA) domain containing 1 [Source:HGNC Symbol;Acc:HGNC:48955]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000219607	0.43	0.659	0.394	0.785	0.688	0.559	37	57	25	50	50	35	PPP1R3G	protein phosphatase 1 regulatory subunit 3G [Source:HGNC Symbol;Acc:HGNC:14945]	-	-	-	-	GO:0000164//protein phosphatase type 1 complex;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0019903//protein phosphatase binding;GO:2001069//glycogen binding	GO:0005979//regulation of glycogen biosynthetic process;GO:0042593//glucose homeostasis;GO:0045725//positive regulation of glycogen biosynthetic process;GO:2000467//positive regulation of glycogen (starch) synthase activity	--
ENSG00000219626	0.669	0.808	1.466	1.596	1.408	1.74	9	19	26.9	25	32	19	FAM228B	family with sequence similarity 228 member B [Source:HGNC Symbol;Acc:HGNC:24736]	-	-	-	-	-	-	-	--
ENSG00000220008	0	0	0	0	0	0.03	0	0	0	0	0	1	LINGO3	leucine rich repeat and Ig domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21206]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	-	--
ENSG00000220201	0.929	1.556	0.683	1.158	0.926	0.721	29.5	40.2	19.64	22.7	26.53	21.29	ZGLP1	zinc finger GATA like protein 1 [Source:HGNC Symbol;Acc:HGNC:37245]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048477//oogenesis;GO:0048599//oocyte development"	zf-GATA
ENSG00000220205	32.381	31.406	32.952	39.559	40.489	36.656	1383.8	1370.37	1049.2	1266.55	1468.25	1140.98	VAMP2	vesicle associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:12643]	Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Genetic Information Processing	"Digestive system;Endocrine system;Nervous system;Excretory system;Folding, sorting and degradation"	ko04970//Salivary secretion;ko04911//Insulin secretion;ko04721//Synaptic vesicle cycle;ko04962//Vasopressin-regulated water reabsorption;ko04130//SNARE interactions in vesicular transport	K13504;K13504;K13504;K13504;K13504	GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0008021//synaptic vesicle;GO:0008076//voltage-gated potassium channel complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030136//clathrin-coated vesicle;GO:0030141//secretory granule;GO:0030667//secretory granule membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0042589//zymogen granule membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0110165//cellular anatomical entity	GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005543//phospholipid binding;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding;GO:0043621//protein self-association;GO:0048306//calcium-dependent protein binding	GO:0006887//exocytosis;GO:0006906//vesicle fusion;GO:0009749//response to glucose;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0016192//vesicle-mediated transport;GO:0017156//calcium-ion regulated exocytosis;GO:0017157//regulation of exocytosis;GO:0032869//cellular response to insulin stimulus;GO:0035493//SNARE complex assembly;GO:0043001//Golgi to plasma membrane protein transport;GO:0043308//eosinophil degranulation;GO:0048488//synaptic vesicle endocytosis;GO:0060291//long-term synaptic potentiation;GO:0060627//regulation of vesicle-mediated transport;GO:0061025//membrane fusion;GO:0065003//protein-containing complex assembly;GO:0090316//positive regulation of intracellular protein transport;GO:1902259//regulation of delayed rectifier potassium channel activity	--
ENSG00000220948	0	0.03	0	0	0	0	0	1	0	0	0	0	TRIM51GP	"tripartite motif-containing 51G, pseudogene [Source:HGNC Symbol;Acc:HGNC:43972]"	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000221813	0	0	0	0	0	0	0	0	0	0	0	0	OR6B1	olfactory receptor family 6 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:8354]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221818	0	0	0	0	0.011	0	0	0	0	0	1	0	EBF2	EBF transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:19090]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0001709//cell fate determination;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0035563//positive regulation of chromatin binding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050873//brown fat cell differentiation;GO:0060612//adipose tissue development;GO:0120162//positive regulation of cold-induced thermogenesis"	COE
ENSG00000221821	3.462	5.683	5.86	5.959	6.967	5.948	40	66	50	51	68	50	C6orf226	chromosome 6 open reading frame 226 [Source:HGNC Symbol;Acc:HGNC:34431]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000221823	16.377	15.366	14.847	14.55	13.391	16.331	966.15	968.79	683.5	676	698.98	717.38	PPP3R1	"protein phosphatase 3 regulatory subunit B, alpha [Source:HGNC Symbol;Acc:HGNC:9317]"	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Development and regeneration;Signal transduction;Signal transduction;Cell growth and death;Endocrine system;Immune system;Cell growth and death;Development and regeneration;Nervous system;Immune system;Immune system;Immune system;Endocrine system;Immune system;Cancer: overview;Endocrine system;Substance dependence;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05020//Prion disease;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko04022//cGMP-PKG signaling pathway;ko04310//Wnt signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04662//B cell receptor signaling pathway;ko04114//Oocyte meiosis;ko04380//Osteoclast differentiation;ko04724//Glutamatergic synapse;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04370//VEGF signaling pathway	K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268;K06268	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005955//calcineurin complex;GO:0008287//protein serine/threonine phosphatase complex;GO:0016020//membrane;GO:0042383//sarcolemma	GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0016018//cyclosporin A binding;GO:0019902//phosphatase binding;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding	GO:0006470//protein dephosphorylation;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1905665//positive regulation of calcium ion import across plasma membrane;GO:1905949//negative regulation of calcium ion import across plasma membrane	--
ENSG00000221826	0	0	0	0	0	0	0	0	0	0	0	0	PSG3	pregnancy specific beta-1-glycoprotein 3 [Source:HGNC Symbol;Acc:HGNC:9520]	-	-	-	-	GO:0005576//extracellular region	-	GO:0006952//defense response;GO:0007565//female pregnancy	--
ENSG00000221829	3.707	4.081	3.483	4.621	5.788	3.871	191	216	132	177	241	147	FANCG	FA complementation group G [Source:HGNC Symbol;Acc:HGNC:3588]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K10894	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043240//Fanconi anaemia nuclear complex	GO:0003684//damaged DNA binding;GO:0005515//protein binding	GO:0001541//ovarian follicle development;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007005//mitochondrion organization;GO:0007286//spermatid development;GO:0009314//response to radiation;GO:0036297//interstrand cross-link repair	--
ENSG00000221836	0	0	0	0	0	0	0	0	0	0	0	0	OR2A5	olfactory receptor family 2 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:8232]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221837	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-9	keratin associated protein 10-9 [Source:HGNC Symbol;Acc:HGNC:22971]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000221838	7.619	8.252	7.749	7.158	6.525	5.696	265.74	312.72	209.8	184.14	202.34	153.62	AP4M1	adaptor related protein complex 4 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:574]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12402	GO:0005768//endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0030124//AP-4 adaptor complex;GO:0030131//clathrin adaptor complex;GO:0031410//cytoplasmic vesicle;GO:0031904//endosome lumen;GO:0032588//trans-Golgi network membrane;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0019904//protein domain specific binding	GO:0000045//autophagosome assembly;GO:0006605//protein targeting;GO:0006622//protein targeting to lysosome;GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006895//Golgi to endosome transport;GO:0008104//protein localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0071806//protein transmembrane transport;GO:0090160//Golgi to lysosome transport;GO:1903361//protein localization to basolateral plasma membrane	--
ENSG00000221840	0	0	0	0	0	0	0	0	0	0	0	0	OR4A5	olfactory receptor family 4 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:15162]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221843	0.276	0.281	0.263	0.25	0.233	0.263	94	96	66	63	67	65	C2orf16	chromosome 2 open reading frame 16 [Source:HGNC Symbol;Acc:HGNC:25275]	-	-	-	-	-	-	-	--
ENSG00000221852	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP1-5	keratin associated protein 1-5 [Source:HGNC Symbol;Acc:HGNC:16777]	-	-	-	-	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000221855	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R41	taste 2 receptor member 41 [Source:HGNC Symbol;Acc:HGNC:18883]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000221858	0	0	0	0	0	0	0	0	0	0	0	0	OR2A12	olfactory receptor family 2 subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:15082]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221859	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-10	keratin associated protein 10-10 [Source:HGNC Symbol;Acc:HGNC:22972]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000221864	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP12-2	keratin associated protein 12-2 [Source:HGNC Symbol;Acc:HGNC:20530]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000221866	4.082	4.123	1.673	0.717	0.833	0.547	1091	1075	339	124	188	107	PLXNA4	plexin A4 [Source:HGNC Symbol;Acc:HGNC:9102]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K06820	GO:0002116//semaphorin receptor complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017154//semaphorin receptor activity	GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008045//motor neuron axon guidance;GO:0008360//regulation of cell shape;GO:0021602//cranial nerve morphogenesis;GO:0021610//facial nerve morphogenesis;GO:0021612//facial nerve structural organization;GO:0021615//glossopharyngeal nerve morphogenesis;GO:0021636//trigeminal nerve morphogenesis;GO:0021637//trigeminal nerve structural organization;GO:0021644//vagus nerve morphogenesis;GO:0021784//postganglionic parasympathetic fiber development;GO:0021785//branchiomotor neuron axon guidance;GO:0021793//chemorepulsion of branchiomotor axon;GO:0021960//anterior commissure morphogenesis;GO:0030334//regulation of cell migration;GO:0035050//embryonic heart tube development;GO:0043087//regulation of GTPase activity;GO:0048485//sympathetic nervous system development;GO:0048812//neuron projection morphogenesis;GO:0048841//regulation of axon extension involved in axon guidance;GO:0050772//positive regulation of axonogenesis;GO:0050923//regulation of negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0097492//sympathetic neuron axon guidance;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance	--
ENSG00000221867	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA3	MAGE family member A3 [Source:HGNC Symbol;Acc:HGNC:6801]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum	GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0089720//caspase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0010507//negative regulation of autophagy;GO:0010955//negative regulation of protein processing;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	--
ENSG00000221869	6.508	7.471	5.944	5.251	5.834	4.234	169	195	114	101	128	80	CEBPD	CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0090575//RNA polymerase II transcription regulator complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0002244//hematopoietic progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0045444//fat cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048839//inner ear development;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000221874	0.231	0.613	0.313	0.387	0.137	0.106	6	16	6	7.45	3	2	ZNF816-ZNF321P	ZNF816-ZNF321P readthrough [Source:HGNC Symbol;Acc:HGNC:38879]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000221878	0	0	0	0	0	0	0	0	0	0	0	0	PSG7	pregnancy specific beta-1-glycoprotein 7 [Source:HGNC Symbol;Acc:HGNC:9524]	-	-	-	-	GO:0005576//extracellular region	-	GO:0007565//female pregnancy	--
ENSG00000221880	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP1-3	keratin associated protein 1-3 [Source:HGNC Symbol;Acc:HGNC:16771]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0030280//structural constituent of skin epidermis	GO:0008150//biological_process	--
ENSG00000221882	0	0	0	0	0	0	0	0	0	0	0	0	OR3A2	olfactory receptor family 3 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8283]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221886	2.911	2.518	1.909	1.514	2.65	1.463	165	139	77	64	124	62	ZBED8	zinc finger BED-type containing 8 [Source:HGNC Symbol;Acc:HGNC:30804]	-	-	-	-	GO:0005654//nucleoplasm	GO:0005515//protein binding	-	--
ENSG00000221887	0.069	0.205	0.124	0.186	0.054	0.095	3	9	4	6	2	3	HMSD	histocompatibility minor serpin domain containing [Source:HGNC Symbol;Acc:HGNC:23037]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0002253//activation of immune response;GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0019835//cytolysis;GO:0032729//positive regulation of interferon-gamma production	--
ENSG00000221888	0	0	0	0	0	0	0	0	0	0	0	0	OR1C1	olfactory receptor family 1 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8182]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221890	5.698	5.52	4.602	3.986	4.18	3.728	689	671	411	357	427	328	NPTXR	neuronal pentraxin receptor [Source:HGNC Symbol;Acc:HGNC:7954]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0098978//glutamatergic synapse	GO:0046872//metal ion binding	GO:0098962//regulation of postsynaptic neurotransmitter receptor activity	--
ENSG00000221900	0	0	0	0	0	0	0	0	0	0	0	0	POM121L12	POM121 transmembrane nucleoporin like 12 [Source:HGNC Symbol;Acc:HGNC:25369]	-	-	-	-	GO:0005643//nuclear pore	GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus	--
ENSG00000221909	4.577	3.786	4.06	3.798	2.878	3.947	227	185	149	144	123	147	FAM200A	family with sequence similarity 200 member A [Source:HGNC Symbol;Acc:HGNC:25401]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000221910	0	0	0	0	0	0	0	0	0	0	0	0	OR2F2	olfactory receptor family 2 subfamily F member 2 [Source:HGNC Symbol;Acc:HGNC:8247]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221914	13.758	12.909	11.117	9.952	12.011	11.696	720	668	438	387	512	449	PPP2R2A	protein phosphatase 2 regulatory subunit Balpha [Source:HGNC Symbol;Acc:HGNC:9304]	Environmental Information Processing;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Genetic Information Processing	Signal transduction;Infectious disease: viral;Cellular community - eukaryotes;Infectious disease: viral;Signal transduction;Circulatory system;Nervous system;Signal transduction;Signal transduction;Infectious disease: parasitic;Translation	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04390//Hippo signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04728//Dopaminergic synapse;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko05142//Chagas disease;ko03015//mRNA surveillance pathway	K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354;K04354	GO:0000159//protein phosphatase type 2A complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0019888//protein phosphatase regulator activity	GO:0006470//protein dephosphorylation;GO:0043278//response to morphine;GO:0050790//regulation of catalytic activity;GO:0070262//peptidyl-serine dephosphorylation	--
ENSG00000221916	0	0.129	0	0	0.461	0.089	0	2	0	0	6	1	C19orf73	chromosome 19 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:25534]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000221923	1.69	1.883	1.934	2.377	0.81	1.799	56	47	28	36	22	27	ZNF880	zinc finger protein 880 [Source:HGNC Symbol;Acc:HGNC:37249]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000221926	15.27	16.12	17.124	14.406	13.01	15.699	531.32	594	512	471	457.41	487.7	TRIM16	tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016605//PML body	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0019966//interleukin-1 binding;GO:0032089//NACHT domain binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0032526//response to retinoic acid;GO:0032731//positive regulation of interleukin-1 beta production;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046683//response to organophosphorus;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0060416//response to growth hormone"	--
ENSG00000221931	0	0	0	0	0	0	0	0	0	0	0	0	OR6X1	olfactory receptor family 6 subfamily X member 1 [Source:HGNC Symbol;Acc:HGNC:14737]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221932	0.104	0.03	0.063	0	0.082	0.046	3.1	0.9	1.38	0	2.05	1	HEPN1	"hepatocellular carcinoma, down-regulated 1 [Source:HGNC Symbol;Acc:HGNC:34400]"	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000221933	0	0	0	0	0	0	0	0	0	0	0	0	OR2A25	olfactory receptor family 2 subfamily A member 25 [Source:HGNC Symbol;Acc:HGNC:19562]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221937	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R40	taste 2 receptor member 40 [Source:HGNC Symbol;Acc:HGNC:18885]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000221938	0	0	0	0	0	0	0	0	0	0	0	0	OR2A14	olfactory receptor family 2 subfamily A member 14 [Source:HGNC Symbol;Acc:HGNC:15084]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221944	0.52	0.302	0.303	0.312	0.274	0.268	72	42	31	32	32	27	TIGD1	tigger transposable element derived 1 [Source:HGNC Symbol;Acc:HGNC:14523]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding	-	--
ENSG00000221946	0	0.135	0.277	0	0.081	0.187	0	2	3	0	1	2	FXYD7	FXYD domain containing ion transport regulator 7 [Source:HGNC Symbol;Acc:HGNC:4034]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0043269//regulation of ion transport;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000221947	0.055	0.053	0	0	0.032	0.037	3	2	0	0	1	1	XKR9	XK related 9 [Source:HGNC Symbol;Acc:HGNC:20937]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006915//apoptotic process;GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902742//apoptotic process involved in development	--
ENSG00000221954	0	0	0	0	0	0	0	0	0	0	0	0	OR4C12	olfactory receptor family 4 subfamily C member 12 [Source:HGNC Symbol;Acc:HGNC:15168]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221955	5.982	6.872	3.789	5.653	6.129	4.89	392	425	188	278	341	242	SLC12A8	solute carrier family 12 member 8 [Source:HGNC Symbol;Acc:HGNC:15595]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0015293//symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015379//potassium:chloride symporter activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0015698//inorganic anion transport;GO:0055064//chloride ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000221957	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000221963	0.307	0.224	0.227	0.356	0.215	0.355	64	47	35	55	38	54	APOL6	apolipoprotein L6 [Source:HGNC Symbol;Acc:HGNC:14870]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process	--
ENSG00000221968	43.67	42.864	50.338	55.193	56.142	66.75	1396	1380	1223	1447	1520	1555	FADS3	fatty acid desaturase 3 [Source:HGNC Symbol;Acc:HGNC:3576]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003674//molecular_function;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006665//sphingolipid metabolic process	--
ENSG00000221970	0.156	0.036	0.052	0.043	0	0.042	15.36	3.61	3.76	3.1	0	3	OR2A1	olfactory receptor family 2 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8229]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221977	0	0	0	0	0	0	0	0	0	0	0	0	OR4E2	olfactory receptor family 4 subfamily E member 2 [Source:HGNC Symbol;Acc:HGNC:8297]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005507//copper ion binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050907//detection of chemical stimulus involved in sensory perception;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221978	21.147	22.05	26.871	26.506	27.178	27.62	912	885	829	811	982	898	CCNL2	cyclin L2 [Source:HGNC Symbol;Acc:HGNC:20570]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0042981//regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0046605//regulation of centrosome cycle;GO:0050790//regulation of catalytic activity;GO:0051726//regulation of cell cycle	--
ENSG00000221983	226.308	214.201	234.12	230.709	197.588	197.609	3048	2915	2347	2314	2281	2009	UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:HGNC Symbol;Acc:HGNC:12458]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Cellular Processes	"Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Folding, sorting and degradation;Translation;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05171//Coronavirus disease - COVID-19;ko05012//Parkinson disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04120//Ubiquitin mediated proteolysis;ko03010//Ribosome;ko04137//Mitophagy - animal	K02927;K02927;K02927;K02927;K02927;K02927;K02927;K02927	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0030666//endocytic vesicle membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding	GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0006464//cellular protein modification process;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process	--
ENSG00000221986	0.539	1.036	0.73	1.309	1.361	0.741	15	29	15	27	32	15	MYBPHL	myosin binding protein H like [Source:HGNC Symbol;Acc:HGNC:30434]	-	-	-	-	GO:0005737//cytoplasm;GO:0030017//sarcomere;GO:0036379//myofilament	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0001701//in utero embryonic development;GO:0008150//biological_process	--
ENSG00000221988	8.078	9.169	12.203	12.242	11.449	12.873	311.48	353.18	353.57	350.48	371.18	361.26	PPT2	palmitoyl-protein thioesterase 2 [Source:HGNC Symbol;Acc:HGNC:9326]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation	K01074;K01074;K01074;K01074	GO:0005764//lysosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0098599//palmitoyl hydrolase activity	GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0098734//macromolecule depalmitoylation	--
ENSG00000221989	0	0	0	0	0	0	0	0	0	0	0	0	OR2A2	olfactory receptor family 2 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8230]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000221994	1.623	1.617	2.195	2.078	1.932	1.884	71	88	59	60	71	66	ZNF630	zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000221996	0	0	0	0	0	0	0	0	0	0	0	0	OR52B4	olfactory receptor family 52 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:15209]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050890//cognition;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000222009	3.309	4.55	2.732	2.201	2.101	3.223	205	238	125	101	110	140	BTBD19	BTB domain containing 19 [Source:HGNC Symbol;Acc:HGNC:27145]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000222011	1.502	2.564	2.231	1.528	1.786	2.534	53	89	52	48	61	66	FAM185A	family with sequence similarity 185 member A [Source:HGNC Symbol;Acc:HGNC:22412]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000222014	0.498	0.527	0.571	0.613	0.459	0.582	31.77	33.74	26.89	28.95	24.71	27	RAB6C	"RAB6C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16525]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0012505//endomembrane system	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	"GO:0000278//mitotic cell cycle;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0009410//response to xenobiotic stimulus;GO:0010824//regulation of centrosome duplication;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000222018	0.803	0.799	0.645	0.373	0.742	0.689	16	16	9.5	5.5	12.5	10	C21orf140	chromosome 21 open reading frame 140 [Source:HGNC Symbol;Acc:HGNC:39602]	-	-	-	-	-	-	-	--
ENSG00000222028	0	0	0	0	0	0	0	0	0	0	0	0	PSMB11	proteasome subunit beta 11 [Source:HGNC Symbol;Acc:HGNC:31963]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K11598	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0006508//proteolysis;GO:0010498//proteasomal protein catabolic process;GO:0033077//T cell differentiation in thymus;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0051603//proteolysis involved in cellular protein catabolic process"	--
ENSG00000222036	0	0	0	0	0	0	0	0	0	0	0	0	POTEM	POTE ankyrin domain family member M [Source:HGNC Symbol;Acc:HGNC:37096]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000222038	0	0	0	0	0	0	0	0	0	0	0	0	POTEJ	POTE ankyrin domain family member J [Source:HGNC Symbol;Acc:HGNC:37094]	-	-	-	-	GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0001895//retina homeostasis	--
ENSG00000222046	0	0	0	0	0	0	0	0	0	0	0	0	DCDC2B	doublecortin domain containing 2B [Source:HGNC Symbol;Acc:HGNC:32576]	-	-	-	-	GO:0005815//microtubule organizing center;GO:0005874//microtubule	GO:0005515//protein binding	GO:0035556//intracellular signal transduction	--
ENSG00000223350	0	0	0	0	0	0	0	0	0	0	0	0	IGLV9-49	immunoglobulin lambda variable 9-49 [Source:HGNC Symbol;Acc:HGNC:5933]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000223417	0	0	0	0	0	0	0	0	0	0	0	0	TRIM49D1	tripartite motif containing 49D1 [Source:HGNC Symbol;Acc:HGNC:43973]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000223443	0.02	0	0	0	0	0	1	0	0	0	0	0	USP17L2	ubiquitin specific peptidase 17 like family member 2 [Source:HGNC Symbol;Acc:HGNC:34434]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0000165//MAPK cascade;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0010955//negative regulation of protein processing;GO:0016579//protein deubiquitination;GO:0030334//regulation of cell migration;GO:0031064//negative regulation of histone deacetylation;GO:0034260//negative regulation of GTPase activity;GO:0042127//regulation of cell population proliferation;GO:0042981//regulation of apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0050691//regulation of defense response to virus by host;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071586//CAAX-box protein processing;GO:0090315//negative regulation of protein targeting to membrane;GO:0110030//regulation of G2/MI transition of meiotic cell cycle;GO:1900027//regulation of ruffle assembly;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000223496	3.399	3.995	3.806	3.202	3.404	3.696	364	430	301	254	308	288	EXOSC6	exosome component 6 [Source:HGNC Symbol;Acc:HGNC:19055]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12587	GO:0000176//nuclear exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0101019//nucleolar exosome (RNase complex)	GO:0003723//RNA binding	"GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0034475//U4 snRNA 3'-end processing;GO:0045006//DNA deamination;GO:0045190//isotype switching;GO:0045830//positive regulation of isotype switching;GO:0071028//nuclear mRNA surveillance;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing"	--
ENSG00000223501	15.403	16.86	18.343	17.671	17.881	14.954	938	1032	825	798	920	664	VPS52	VPS52 subunit of GARP complex [Source:HGNC Symbol;Acc:HGNC:10518]	-	-	-	-	GO:0000938//GARP complex;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:1990745//EARP complex	GO:0005515//protein binding;GO:0019905//syntaxin binding	"GO:0006896//Golgi to vacuole transport;GO:0007041//lysosomal transport;GO:0010668//ectodermal cell differentiation;GO:0015031//protein transport;GO:0032456//endocytic recycling;GO:0042147//retrograde transport, endosome to Golgi;GO:0048611//embryonic ectodermal digestive tract development"	--
ENSG00000223510	0	0	0.199	0	0	0	0	0	2	0	0	0	CDRT15	CMT1A duplicated region transcript 15 [Source:HGNC Symbol;Acc:HGNC:14395]	-	-	-	-	-	-	-	--
ENSG00000223547	1.169	2.193	0.719	1.516	1.648	0.975	159.81	207.99	72.52	114.13	157.86	79.39	ZNF844	zinc finger protein 844 [Source:HGNC Symbol;Acc:HGNC:25932]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000223569	0	0	0	0	0	0	0	0	0	0	0	0	USP17L15	ubiquitin specific peptidase 17 like family member 15 [Source:HGNC Symbol;Acc:HGNC:44443]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000223572	0.081	0.025	0.161	0.453	0	0.214	1.81	0.55	3.89	11	0	4.19	CKMT1A	"creatine kinase, mitochondrial 1A [Source:HGNC Symbol;Acc:HGNC:31736]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00933;K00933	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004111//creatine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0016310//phosphorylation;GO:0019752//carboxylic acid metabolic process;GO:0046314//phosphocreatine biosynthetic process	--
ENSG00000223573	0.222	0.051	0.07	0	0.191	0.018	8	4	4	0	4	1	TINCR	TINCR ubiquitin domain containing [Source:HGNC Symbol;Acc:HGNC:14607]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000223591	0.401	0.216	0.264	0.284	0.516	0.591	13.47	7.31	6.54	7.06	14.65	14.44	CENPVL1	centromere protein V like 1 [Source:HGNC Symbol;Acc:HGNC:31851]	-	-	-	-	-	GO:0016846//carbon-sulfur lyase activity;GO:0046872//metal ion binding	-	--
ENSG00000223601	0	0	0	0	0	0	0	0	0	0	0	0	EBLN1	endogenous Bornavirus like nucleoprotein 1 [Source:HGNC Symbol;Acc:HGNC:39430]	-	-	-	-	-	-	-	--
ENSG00000223609	0	0	0	0	0	0	0	0	0	0	0	0	HBD	hemoglobin subunit delta [Source:HGNC Symbol;Acc:HGNC:4829]	-	-	-	-	GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031838//haptoglobin-hemoglobin complex;GO:0072562//blood microparticle	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0031720//haptoglobin binding;GO:0031721//hemoglobin alpha binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport;GO:0042744//hydrogen peroxide catabolic process;GO:0098869//cellular oxidant detoxification	--
ENSG00000223611	0	0	0.011	0	0	0	0	0	1	0	0	0	SUPT20HL2	SUPT20H like 2 [Source:HGNC Symbol;Acc:HGNC:31797]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21245	GO:0000124//SAGA complex;GO:0005615//extracellular space	GO:0003712//transcription coregulator activity	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000223614	0	0	0	0	0	0	0	0	0	0	0	0	ZNF735	zinc finger protein 735 [Source:HGNC Symbol;Acc:HGNC:32466]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000223638	0	0	0	0	0	0	0	0	0	0	0	0	RFPL4A	ret finger protein like 4A [Source:HGNC Symbol;Acc:HGNC:16449]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000223648	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-64	immunoglobulin heavy variable 3-64 [Source:HGNC Symbol;Acc:HGNC:5617]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000223658	0	0	0	0	0	0	0	0	0	0	0	0	C1GALT1C1L	C1GALT1 specific chaperone 1 like [Source:HGNC Symbol;Acc:HGNC:51617]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K09653;K09653;K09653	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016263//glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	"GO:0016267//O-glycan processing, core 1"	--
ENSG00000223731	0.013	0.027	0	0	0	0	2	4	0	0	0	0	SUPT20HL1	SUPT20H like 1 [Source:HGNC Symbol;Acc:HGNC:30773]	Cellular Processes	Transport and catabolism	ko04140//Autophagy - animal	K21245	GO:0000124//SAGA complex	GO:0003712//transcription coregulator activity	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000223802	29.185	31.678	29.697	36.574	34.769	42.405	1245.45	1204.8	898.45	1013.67	1028.19	1228.48	CERS1	ceramide synthase 1 [Source:HGNC Symbol;Acc:HGNC:14253]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Lipid metabolism	ko01100//Metabolic pathways;ko04071//Sphingolipid signaling pathway;ko00600//Sphingolipid metabolism	K04710;K04710;K04710	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0050291//sphingosine N-acyltransferase activity	GO:0006629//lipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0036146//cellular response to mycotoxin;GO:0046513//ceramide biosynthetic process;GO:0051974//negative regulation of telomerase activity;GO:0071466//cellular response to xenobiotic stimulus;GO:0071492//cellular response to UV-A;GO:0072721//cellular response to dithiothreitol;GO:1901526//positive regulation of mitophagy	--
ENSG00000223865	0.292	0.408	0.136	0.14	1.329	0.54	7	12	3	3	24	10	HLA-DPB1	"major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0042605//peptide antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0032729//positive regulation of interferon-gamma production;GO:0042102//positive regulation of T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0050870//positive regulation of T cell activation	--
ENSG00000223953	338.54	373.508	418.378	490.704	460.917	463.316	8453.92	9269.41	7684.18	9152.56	9753.96	8397.38	C1QTNF5	C1q and TNF related 5 [Source:HGNC Symbol;Acc:HGNC:14344]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0030133//transport vesicle;GO:0032991//protein-containing complex;GO:0042995//cell projection	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0009306//protein secretion;GO:0048839//inner ear development	--
ENSG00000223997	0	0	0	0	0	0	0	0	0	0	0	0	TRDD1	T cell receptor delta diversity 1 [Source:HGNC Symbol;Acc:HGNC:12254]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000224041	0	0	0	0	0	0	0	0	0	0	0	0	IGKV3D-15	immunoglobulin kappa variable 3D-15 [Source:HGNC Symbol;Acc:HGNC:5824]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000224051	11.303	9.82	10.789	12.842	12.213	13.104	505	441	356	425	461	426	CPTP	ceramide-1-phosphate transfer protein [Source:HGNC Symbol;Acc:HGNC:28116]	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane	GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:0120013//lipid transfer activity;GO:1902387//ceramide 1-phosphate binding;GO:1902388//ceramide 1-phosphate transfer activity	GO:0006687//glycosphingolipid metabolic process;GO:0006869//lipid transport;GO:0010507//negative regulation of autophagy;GO:0032691//negative regulation of interleukin-1 beta production;GO:0035627//ceramide transport;GO:0120009//intermembrane lipid transfer;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1902389//ceramide 1-phosphate transport	--
ENSG00000224089	0	0	0	0	0	0	0	0	0	0	0	0	CT47A10	cancer/testis antigen family 47 member A10 [Source:HGNC Symbol;Acc:HGNC:33291]	-	-	-	-	-	-	-	--
ENSG00000224107	0	0	0	0	0	0	0	0	0	0	0	0	ETDB	embryonic testis differentiation homolog B [Source:HGNC Symbol;Acc:HGNC:44269]	-	-	-	-	-	-	-	--
ENSG00000224109	2.905	2.873	3.308	3.125	3.277	2.664	114.05	113.37	95.93	90.88	108.7	76.11	CENPVL3	centromere protein V like 3 [Source:HGNC Symbol;Acc:HGNC:43880]	-	-	-	-	-	GO:0016846//carbon-sulfur lyase activity;GO:0046872//metal ion binding	-	--
ENSG00000224373	0	0	0	0	0.115	0	0	0	0	0	1	0	IGHV4-59	immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000224383	1.211	0.483	0.719	0.743	0.219	0.522	42	30.08	34.46	24	12	16	PRR29	proline rich 29 [Source:HGNC Symbol;Acc:HGNC:25673]	-	-	-	-	-	-	-	--
ENSG00000224389	131.642	141.995	132.808	127.331	145.668	115.47	14790.83	16062.51	11037.21	10613.54	13853.35	9457.48	C4B	complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03989;K03989;K03989;K03989;K03989;K03989	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0106139//symbiont cell surface	GO:0001848//complement binding;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding	"GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0008228//opsonization;GO:0010951//negative regulation of endopeptidase activity;GO:0032490//detection of molecule of bacterial origin;GO:0045087//innate immune response;GO:2000427//positive regulation of apoptotic cell clearance"	--
ENSG00000224420	0.245	0.061	0	0	0	0.168	4	1	0	0	0	2	ADM5	adrenomedullin 5 (putative) [Source:HGNC Symbol;Acc:HGNC:27293]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003674//molecular_function;GO:0031700//adrenomedullin receptor binding	GO:0003073//regulation of systemic arterial blood pressure;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008150//biological_process;GO:0010460//positive regulation of heart rate;GO:1990410//adrenomedullin receptor signaling pathway	--
ENSG00000224440	0	0	0	0	0	0	0	0	0	0	0	0	CXorf51A	chromosome X open reading frame 51A [Source:HGNC Symbol;Acc:HGNC:30533]	-	-	-	-	-	-	-	--
ENSG00000224470	8.521	8.616	8.708	9.257	9.22	8.922	1400.61	1420.08	1054.12	1123	1278.04	1068.05	ATXN1L	ataxin 1 like [Source:HGNC Symbol;Acc:HGNC:33279]	Human Diseases;Human Diseases;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05017//Spinocerebellar ataxia;ko04330//Notch signaling pathway	K23616;K23616;K23616	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030425//dendrite;GO:0042995//cell projection	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0007612//learning;GO:0007613//memory;GO:0030198//extracellular matrix organization;GO:0035176//social behavior;GO:0048286//lung alveolus development;GO:0048856//anatomical structure development;GO:1902035//positive regulation of hematopoietic stem cell proliferation"	--
ENSG00000224531	8.915	7.862	7.707	7.698	7.158	9.911	886	801	577	578	613	731	SMIM13	small integral membrane protein 13 [Source:HGNC Symbol;Acc:HGNC:27356]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000224578	0.033	0.099	0.045	0.179	0.077	0.046	1.08	3.23	1.08	4.32	2.13	1.09	HNRNPA1P48	heterogeneous nuclear ribonucleoprotein A1 pseudogene 48 [Source:HGNC Symbol;Acc:HGNC:48778]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05014//Amyotrophic lateral sclerosis;ko03040//Spliceosome	K12741;K12741	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000224586	0	0	0	0	0	0	0	0	0	0	0	0	GPX5	glutathione peroxidase 5 [Source:HGNC Symbol;Acc:HGNC:4557]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005576//extracellular region	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0016491//oxidoreductase activity	GO:0006629//lipid metabolic process;GO:0006979//response to oxidative stress;GO:0034599//cellular response to oxidative stress;GO:0098869//cellular oxidant detoxification	--
ENSG00000224650	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-74	immunoglobulin heavy variable 3-74 [Source:HGNC Symbol;Acc:HGNC:5624]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000224659	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12J	G antigen 12J [Source:HGNC Symbol;Acc:HGNC:17778]	-	-	-	-	-	-	-	--
ENSG00000224712	0.154	0.296	0.747	0	0	0.229	3.05	8.34	12.61	0	0	3.3	NPIPA3	nuclear pore complex interacting protein family member A3 [Source:HGNC Symbol;Acc:HGNC:41978]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000224877	16.298	20.544	16.984	19.353	18.079	15.129	191	242	147	168	179	129	NDUFAF8	NADH:ubiquinone oxidoreductase complex assembly factor 8 [Source:HGNC Symbol;Acc:HGNC:33551]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K24726	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000224902	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12H	G antigen 12H [Source:HGNC Symbol;Acc:HGNC:31908]	-	-	-	-	-	-	-	--
ENSG00000224916	0	0	0	0.036	0	0	0	0	0	1	0	0	APOC4-APOC2	APOC4-APOC2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44426]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22287	GO:0005576//extracellular region;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron	GO:0008047//enzyme activator activity	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0016042//lipid catabolic process;GO:0050790//regulation of catalytic activity	--
ENSG00000224940	0.132	0.027	0	0	0	0	5	1	0	0	0	0	PRRT4	proline rich transmembrane protein 4 [Source:HGNC Symbol;Acc:HGNC:37280]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000224960	0	0	0	0	0	0	0	0	0	0	0	0	PPP4R3C	protein phosphatase 4 regulatory subunit 3C [Source:HGNC Symbol;Acc:HGNC:33146]	Organismal Systems;Organismal Systems	Endocrine system;Aging	ko04922//Glucagon signaling pathway;ko04212//Longevity regulating pathway - worm	K17491;K17491	GO:0005654//nucleoplasm;GO:0030289//protein phosphatase 4 complex	GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0050790//regulation of catalytic activity	--
ENSG00000224982	0	0.017	0	0	0	0	0	1	0	0	0	0	TMEM233	transmembrane protein 233 [Source:HGNC Symbol;Acc:HGNC:37219]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000225110	0	0	0	0	0	0.02	0	0	0	0	0	1	PNMA6F	PNMA family member 6F [Source:HGNC Symbol;Acc:HGNC:53119]	-	-	-	-	-	-	-	--
ENSG00000225180	0	0	0	0.05	0	0	0	0	0	1	0	0	PVALEF	parvalbumin like EF-hand containing [Source:HGNC Symbol;Acc:HGNC:40053]	-	-	-	-	GO:0005861//troponin complex	GO:0005509//calcium ion binding;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0051015//actin filament binding	GO:0003009//skeletal muscle contraction;GO:0006937//regulation of muscle contraction	--
ENSG00000225190	10.876	13.442	12.906	14.766	15.192	14.342	742	800	665	654	769	618	PLEKHM1	pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K23282	GO:0005730//nucleolus;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044754//autolysosome	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006914//autophagy;GO:0015031//protein transport;GO:0032418//lysosome localization;GO:0045780//positive regulation of bone resorption;GO:0061909//autophagosome-lysosome fusion;GO:1900029//positive regulation of ruffle assembly;GO:1902774//late endosome to lysosome transport	--
ENSG00000225327	0	0.03	0	0	0	0	0	1	0	0	0	0	USP17L3	ubiquitin specific peptidase 17 like family member 3 [Source:HGNC Symbol;Acc:HGNC:37175]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000225366	0	0	0	0	0	0	0	0	0	0	0	0	TDGF1P3	teratocarcinoma-derived growth factor 1 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:11703]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane	GO:0005102//signaling receptor binding;GO:0008083//growth factor activity;GO:0038100//nodal binding;GO:0070697//activin receptor binding	GO:0001568//blood vessel development;GO:0007165//signal transduction;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0009952//anterior/posterior pattern specification;GO:0038092//nodal signaling pathway;GO:0048856//anatomical structure development	--
ENSG00000225396	0	0	0	0	0	0	0	0	0	0	0	0	FAM236D	family with sequence similarity 236 member D [Source:HGNC Symbol;Acc:HGNC:52642]	-	-	-	-	-	-	-	--
ENSG00000225523	0	0	0	0	0	0	0	0	0	0	0	0	IGKV6D-21	immunoglobulin kappa variable 6D-21 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5837]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000225526	0	0	0	0.266	0.063	0.074	0	0	0	4	1	1	MKRN2OS	MKRN2 opposite strand [Source:HGNC Symbol;Acc:HGNC:40375]	-	-	-	-	-	-	-	--
ENSG00000225528	0.073	0	0	0	0	0.15	2	0	0	0	0	3	--	novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7	-	-	-	-	-	-	-	--
ENSG00000225556	0.193	0.48	0.218	0.521	0.219	0.113	6	15	5	12	6	3	C2CD4D	C2 calcium dependent domain containing 4D [Source:HGNC Symbol;Acc:HGNC:37210]	-	-	-	-	-	-	-	--
ENSG00000225614	1.209	1.365	1.083	0.822	0.924	0.708	339	392	223	174	216	146	ZNF469	zinc finger protein 469 [Source:HGNC Symbol;Acc:HGNC:23216]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046872//metal ion binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:1903053//regulation of extracellular matrix organization	zf-C2H2
ENSG00000225663	37.771	42.521	43.222	53.148	47.791	47.817	925	945	776	942	898	822	MCRIP1	MAPK regulated corepressor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:28007]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule	GO:0005515//protein binding	GO:0010717//regulation of epithelial to mesenchymal transition	--
ENSG00000225697	1.601	1.987	2.844	2.3	2.477	3.075	87	83	93	86	95	93	SLC26A6	solute carrier family 26 member 6 [Source:HGNC Symbol;Acc:HGNC:14472]	Human Diseases;Organismal Systems	Cancer: overview;Digestive system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko04978//Mineral absorption	K14704;K14704	GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0012506//vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0031982//vesicle;GO:0034707//chloride channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097225//sperm midpiece	GO:0005254//chloride channel activity;GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015499//formate transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0015660//formate efflux transmembrane transporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding	GO:0006811//ion transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0008272//sulfate transport;GO:0015701//bicarbonate transport;GO:0015724//formate transport;GO:0015797//mannitol transport;GO:0019532//oxalate transport;GO:0030321//transepithelial chloride transport;GO:0042045//epithelial fluid transport;GO:0046724//oxalic acid secretion;GO:0048240//sperm capacitation;GO:0050892//intestinal absorption;GO:0051453//regulation of intracellular pH;GO:0051454//intracellular pH elevation;GO:0055085//transmembrane transport;GO:0070633//transepithelial transport;GO:0071320//cellular response to cAMP;GO:0071332//cellular response to fructose stimulus;GO:0071346//cellular response to interferon-gamma;GO:0098656//anion transmembrane transport;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport;GO:2001150//positive regulation of dipeptide transmembrane transport	--
ENSG00000225698	0	0	0	0	0.131	0	0	0	0	0	1	0	IGHV3-72	immunoglobulin heavy variable 3-72 [Source:HGNC Symbol;Acc:HGNC:5622]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000225781	0	0	0	0	0	0	0	0	0	0	0	0	OR6V1	olfactory receptor family 6 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:15090]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000225805	0	0	0	0	0	0	0	0	0	0	0	0	DEFB131B	defensin beta 131B [Source:HGNC Symbol;Acc:HGNC:38058]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	-	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0045087//innate immune response	--
ENSG00000225825	0	0	0	0	0	0	0	0	0	0	0	0	IGHD6-25	immunoglobulin heavy diversity 6-25 [Source:HGNC Symbol;Acc:HGNC:5516]	-	-	-	-	-	-	-	--
ENSG00000225828	0.512	0.663	0.971	1.66	1.213	0.493	10	13	14	24	20	7	FAM229A	family with sequence similarity 229 member A [Source:HGNC Symbol;Acc:HGNC:44652]	-	-	-	-	-	-	-	--
ENSG00000225830	6.971	5.402	5.298	4.249	5.024	6.335	886	713	518	374	512	551	ERCC6	"ERCC excision repair 6, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:3438]"	Genetic Information Processing	Replication and repair	ko03420//Nucleotide excision repair	K10841	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex;GO:0016604//nuclear body;GO:0090734//site of DNA damage;GO:0110016//B-WICH complex	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0030296//protein tyrosine kinase activator activity;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding;GO:0047485//protein N-terminus binding;GO:0140658//ATP-dependent chromatin remodeler activity"	"GO:0000012//single strand break repair;GO:0000077//DNA damage checkpoint signaling;GO:0000303//response to superoxide;GO:0002230//positive regulation of defense response to virus by host;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006284//base-excision repair;GO:0006290//pyrimidine dimer repair;GO:0006338//chromatin remodeling;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007399//nervous system development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009411//response to UV;GO:0009636//response to toxic substance;GO:0010165//response to X-ray;GO:0010224//response to UV-B;GO:0010332//response to gamma radiation;GO:0010628//positive regulation of gene expression;GO:0022008//neurogenesis;GO:0030182//neuron differentiation;GO:0031175//neuron projection development;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:0035066//positive regulation of histone acetylation;GO:0035264//multicellular organism growth;GO:0042262//DNA protection;GO:0045494//photoreceptor cell maintenance;GO:0045739//positive regulation of DNA repair;GO:0045943//positive regulation of transcription by RNA polymerase I;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0097680//double-strand break repair via classical nonhomologous end joining;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining"	--
ENSG00000225899	0	0	0	0	0	0	0	0	0	0	0	0	FRG2B	FSHD region gene 2 family member B [Source:HGNC Symbol;Acc:HGNC:33518]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000225921	19.107	15.361	17.687	14.502	14.885	14.921	667	539	456	375	439	379	NOL7	nucleolar protein 7 [Source:HGNC Symbol;Acc:HGNC:21040]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000225950	0.049	0.08	0	0.06	0.096	0.222	1	2	0	2	2	4	NTF4	neurotrophin 4 [Source:HGNC Symbol;Acc:HGNC:8024]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Nervous system	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04722//Neurotrophin signaling pathway	K12457;K12457;K12457;K12457	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0008021//synaptic vesicle;GO:0030424//axon;GO:0030425//dendrite	GO:0005102//signaling receptor binding;GO:0005163//nerve growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007402//ganglion mother cell fate determination;GO:0007422//peripheral nervous system development;GO:0007613//memory;GO:0007616//long-term memory;GO:0008052//sensory organ boundary specification;GO:0008344//adult locomotory behavior;GO:0008544//epidermis development;GO:0021675//nerve development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038180//nerve growth factor signaling pathway;GO:0042490//mechanoreceptor differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0048812//neuron projection morphogenesis;GO:0050804//modulation of chemical synaptic transmission;GO:0060384//innervation;GO:0060548//negative regulation of cell death;GO:0061193//taste bud development	--
ENSG00000225968	23.452	24.89	25.946	28.027	31.677	31.374	1724	1821	1395	1508	1927	1648	ELFN1	extracellular leucine rich repeat and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33154]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031012//extracellular matrix;GO:0042995//cell projection;GO:0060076//excitatory synapse	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0043086//negative regulation of catalytic activity;GO:0050808//synapse organization	--
ENSG00000225973	3.185	3.649	2.806	2.329	2.07	2.232	58.48	68	37	33	33	30	PIGBOS1	PIGB opposite strand 1 [Source:HGNC Symbol;Acc:HGNC:50696]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031307//integral component of mitochondrial outer membrane	GO:0005515//protein binding	GO:0006986//response to unfolded protein;GO:1900101//regulation of endoplasmic reticulum unfolded protein response	--
ENSG00000225997	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000226023	0	0	0	0	0	0	0	0	0	0	0	0	CT47A6	cancer/testis antigen family 47 member A6 [Source:HGNC Symbol;Acc:HGNC:33287]	-	-	-	-	-	-	-	--
ENSG00000226124	0.666	0.804	0.834	1.574	1.331	0.749	18	25	28	29	34	22	FTCDNL1	formiminotransferase cyclodeaminase N-terminal like [Source:HGNC Symbol;Acc:HGNC:48661]	-	-	-	-	-	GO:0005542//folic acid binding;GO:0016740//transferase activity	-	--
ENSG00000226174	0	0.073	0	0.124	0.022	0.127	0	4	0	5	1	5	TEX22	testis expressed 22 [Source:HGNC Symbol;Acc:HGNC:40026]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	-	-	--
ENSG00000226288	0	0	0	0	0	0.02	0	0	0	0	0	2	OR52I2	olfactory receptor family 52 subfamily I member 2 [Source:HGNC Symbol;Acc:HGNC:15221]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000226314	0.664	0.383	0.481	0.2	0.245	0.244	23	13	12	5	7	6	ZKSCAN8P1	ZKSCAN8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:18777]	-	-	-	-	-	-	-	--
ENSG00000226321	0.081	0.098	0.024	0.061	0.021	0.086	9	11	2	5	2	7	CROCC2	"ciliary rootlet coiled-coil, rootletin family member 2 [Source:HGNC Symbol;Acc:HGNC:51677]"	-	-	-	-	-	-	-	--
ENSG00000226372	0	0	0	0	0	0	0	0	0	0	0	0	DCAF8L1	DDB1 and CUL4 associated factor 8 like 1 [Source:HGNC Symbol;Acc:HGNC:31810]	-	-	-	-	GO:0005737//cytoplasm;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	-	--
ENSG00000226430	0	0	0	0	0	0	0	0	0	0	0	0	USP17L7	ubiquitin specific peptidase 17 like family member 7 [Source:HGNC Symbol;Acc:HGNC:37180]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000226479	11.104	11.072	11.298	11.419	12.739	11.704	1364	1367	1025	1039	1322	1046	TMEM185B	transmembrane protein 185B [Source:HGNC Symbol;Acc:HGNC:18896]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000226490	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000226600	0	0	0	0	0	0	0	0	0	0	0	0	CT47A9	cancer/testis antigen family 47 member A9 [Source:HGNC Symbol;Acc:HGNC:33290]	-	-	-	-	-	-	-	--
ENSG00000226650	0	0	0	0	0	0	0	0	0	0	0	0	KIF4B	kinesin family member 4B [Source:HGNC Symbol;Acc:HGNC:6322]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016363//nuclear matrix	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding	GO:0000281//mitotic cytokinesis;GO:0007018//microtubule-based movement;GO:0007052//mitotic spindle organization;GO:0051256//mitotic spindle midzone assembly	--
ENSG00000226685	0	0	0	0	0	0	0	0	0	0	0	0	CT47A12	cancer/testis antigen family 47 member A12 [Source:HGNC Symbol;Acc:HGNC:33292]	-	-	-	-	-	-	-	--
ENSG00000226690	0	0.079	0	0	0	0	0	2	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000226742	4.469	4.707	5.431	4.994	4.958	6.666	64	68	58	53	60	70	HSBP1L1	heat shock factor binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:37243]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0045892//negative regulation of transcription, DNA-templated;GO:0070370//cellular heat acclimation"	--
ENSG00000226761	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R46	taste 2 receptor member 46 [Source:HGNC Symbol;Acc:HGNC:18877]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000226763	0.1	0.1	0.218	0.135	0.024	0.025	5.02	5.02	9.02	5.01	1	1	SRRM5	serine/arginine repetitive matrix 5 [Source:HGNC Symbol;Acc:HGNC:37248]	-	-	-	-	-	-	-	--
ENSG00000226784	0	0	0	0	0	0	0	0	0	0	0	0	PGAM4	phosphoglycerate mutase family member 4 [Source:HGNC Symbol;Acc:HGNC:21731]	Metabolism;Metabolism;Organismal Systems;Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Endocrine system;Global and overview maps;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko04922//Glucagon signaling pathway;ko01230//Biosynthesis of amino acids;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00260//Glycine, serine and threonine metabolism"	K01834;K01834;K01834;K01834;K01834;K01834;K01834	GO:0070062//extracellular exosome;GO:0097228//sperm principal piece	"GO:0003824//catalytic activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0016787//hydrolase activity;GO:0016853//isomerase activity;GO:0016868//intramolecular transferase activity, phosphotransferases"	GO:0006096//glycolytic process;GO:1902093//positive regulation of flagellated sperm motility	--
ENSG00000226792	0	0	0	0	0	0	0	0	0	0	0	0	C13orf42	chromosome 13 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:42693]	-	-	-	-	-	-	-	--
ENSG00000226807	0	0	0	0	0	0	0	0	0	0	0	0	MROH5	maestro heat like repeat family member 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:42976]	-	-	-	-	-	-	-	--
ENSG00000226887	0.777	1.084	0.575	0.607	0.696	0.611	46	65	26	31	37	28	ERVMER34-1	"endogenous retrovirus group MER34 member 1, envelope [Source:HGNC Symbol;Acc:HGNC:42970]"	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000226929	0	0	0	0	0	0	0	0	0	0	0	0	CT47A11	cancer/testis antigen family 47 member A11 [Source:HGNC Symbol;Acc:HGNC:27397]	-	-	-	-	-	-	-	--
ENSG00000226941	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1J	RNA binding motif protein Y-linked family 1 member J [Source:HGNC Symbol;Acc:HGNC:23917]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing"	--
ENSG00000226979	0	0	0	0.043	0.114	0	0	0	0	1	3	0	LTA	lymphotoxin alpha [Source:HGNC Symbol;Acc:HGNC:6709]	Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases	Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Signal transduction;Signal transduction;Signaling molecules and interaction;Endocrine and metabolic disease	ko05168//Herpes simplex virus 1 infection;ko04060//Cytokine-cytokine receptor interaction;ko05166//Human T-cell leukemia virus 1 infection;ko04064//NF-kappa B signaling pathway;ko04668//TNF signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04940//Type I diabetes mellitus	K05468;K05468;K05468;K05468;K05468;K05468;K05468	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0001666//response to hypoxia;GO:0002876//positive regulation of chronic inflammatory response to antigenic stimulus;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007584//response to nutrient;GO:0009410//response to xenobiotic stimulus;GO:0032496//response to lipopolysaccharide;GO:0032729//positive regulation of interferon-gamma production;GO:0043065//positive regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0048535//lymph node development;GO:0050830//defense response to Gram-positive bacterium;GO:0060252//positive regulation of glial cell proliferation	--
ENSG00000227051	10.247	10.05	10.179	8.959	9.779	8.384	1621	1598	1128	995	1307	911	C14orf132	chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000227057	15.954	16.405	16.713	19.149	16.513	16.517	685	708	530	609	599	516	WDR46	WD repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:13923]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032040//small-subunit processome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000227059	0	0	0	0	0	0	0	0	0	0	0	0	ANHX	anomalous homeobox [Source:HGNC Symbol;Acc:HGNC:40024]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0001654//eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000227108	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1-14	immunoglobulin heavy diversity 1-14 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5483]	-	-	-	-	-	-	-	--
ENSG00000227124	0.682	0.776	1.036	1.163	1.024	0.857	31	27	32	21	24	13	ZNF717	zinc finger protein 717 [Source:HGNC Symbol;Acc:HGNC:29448]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000227140	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L5	ubiquitin specific peptidase 17 like family member 5 [Source:HGNC Symbol;Acc:HGNC:37177]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000227151	0	0	0	0	0	0	0	0	0	0	0	0	PRR20D	proline rich 20D [Source:HGNC Symbol;Acc:HGNC:37222]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000227152	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000227191	0	0	0	0	0	0	0	0	0	0	0	0	TRGC2	T cell receptor gamma constant 2 [Source:HGNC Symbol;Acc:HGNC:12276]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000227196	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000227234	0	0	0	0	0	0	0	0	0	0	0	0	SPANXB1	SPANX family member B1 [Source:HGNC Symbol;Acc:HGNC:14329]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007286//spermatid development	--
ENSG00000227268	0.121	0.175	0.283	0.149	0.222	0.318	11	16	19	10	17	21	KLLN	"killin, p53 regulated DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:37212]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0003677//DNA binding	GO:0006915//apoptotic process;GO:0007049//cell cycle	--
ENSG00000227345	7.408	5.81	5.956	4.331	4.919	5.128	606	484	369	275	339	307	PARG	poly(ADP-ribose) glycohydrolase [Source:HGNC Symbol;Acc:HGNC:8605]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0004649//poly(ADP-ribose) glycohydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity	"GO:0005975//carbohydrate metabolic process;GO:0006282//regulation of DNA repair;GO:0006287//base-excision repair, gap-filling;GO:0006974//cellular response to DNA damage stimulus;GO:0009225//nucleotide-sugar metabolic process;GO:0031056//regulation of histone modification;GO:1990966//ATP generation from poly-ADP-D-ribose"	--
ENSG00000227471	0	0	0	0	0	0	0	0	0	0	0	0	AKR1B15	aldo-keto reductase family 1 member B15 [Source:HGNC Symbol;Acc:HGNC:37281]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00561//Glycerolipid metabolism;ko00040//Pentose and glucuronate interconversions;ko00051//Fructose and mannose metabolism;ko00052//Galactose metabolism;ko00790//Folate biosynthesis	K00011;K00011;K00011;K00011;K00011;K00011	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0047655//allyl-alcohol dehydrogenase activity;GO:0047886//farnesol dehydrogenase activity;GO:0052650//NADP-retinol dehydrogenase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity"	GO:0006629//lipid metabolic process;GO:0006703//estrogen biosynthetic process;GO:0042572//retinol metabolic process	--
ENSG00000227488	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12D	G antigen 12D [Source:HGNC Symbol;Acc:HGNC:31904]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000227500	40.81	43.781	45.355	51.142	50.651	46.628	2045	2269	1647	1954.29	2147	1697	SCAMP4	secretory carrier membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:30385]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0110165//cellular anatomical entity	GO:0005515//protein binding	GO:0015031//protein transport	--
ENSG00000227507	0	0	0	0.073	0.064	0.148	0	0	0	1	1	2	LTB	lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]	Environmental Information Processing;Environmental Information Processing;Human Diseases	Signaling molecules and interaction;Signal transduction;Immune disease	ko04060//Cytokine-cytokine receptor interaction;ko04064//NF-kappa B signaling pathway;ko05323//Rheumatoid arthritis	K03157;K03157;K03157	GO:0005575//cellular_component;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010467//gene expression;GO:0032735//positive regulation of interleukin-12 production;GO:0043588//skin development;GO:0048535//lymph node development	--
ENSG00000227551	0	0	0	0	0	0	0	0	0	0	0	0	USP17L12	ubiquitin specific peptidase 17 like family member 12 [Source:HGNC Symbol;Acc:HGNC:44440]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000227717	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L25P	"golgin A6 family like 25, pseudogene [Source:HGNC Symbol;Acc:HGNC:55711]"	-	-	-	-	-	-	-	--
ENSG00000227729	0.136	0.101	0.138	0.046	0.241	0.093	4	3	3	1	6	2	RD3L	RD3 like [Source:HGNC Symbol;Acc:HGNC:40912]	-	-	-	-	-	-	-	--
ENSG00000227800	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000227868	0	0	0	0	0	0	0	0	0	0	0	0	TEX46	testis expressed 46 [Source:HGNC Symbol;Acc:HGNC:44651]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000227877	0	0	0	0	0	0	0	0	0	0	0	0	MRLN	myoregulin [Source:HGNC Symbol;Acc:HGNC:48649]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane	GO:0004857//enzyme inhibitor activity	GO:0009611//response to wounding;GO:0043086//negative regulation of catalytic activity;GO:1901877//negative regulation of calcium ion binding;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1902081//negative regulation of calcium ion import into sarcoplasmic reticulum	--
ENSG00000228049	1.321	1.639	2.568	2.841	1.138	3.253	56.57	70.58	56.99	62.38	41.18	25.69	POLR2J2	RNA polymerase II subunit J2 [Source:HGNC Symbol;Acc:HGNC:23208]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03008;K03008	"GO:0005634//nucleus;GO:0005665//RNA polymerase II, core complex"	GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000228075	0	0	0	0	0	0	0	0	0	0	0	0	BOD1L2	biorientation of chromosomes in cell division 1 like 2 [Source:HGNC Symbol;Acc:HGNC:28505]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000922//spindle pole;GO:0000940//outer kinetochore;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0005876//spindle microtubule"	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding	GO:0007049//cell cycle;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0051301//cell division	--
ENSG00000228083	0	0	0	0	0	0	0	0	0	0	0	0	IFNA14	interferon alpha 14 [Source:HGNC Symbol;Acc:HGNC:5420]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000228131	0	0	0	0	0	0	0	0	0	0	0	0	IGHD6-6	immunoglobulin heavy diversity 6-6 [Source:HGNC Symbol;Acc:HGNC:5517]	-	-	-	-	-	-	-	--
ENSG00000228144	0	0	0	0.2	0	0.189	0	0	0	3.03	0	2.81	TMBIM4	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000228198	0	0	0	0	0	0	0	0	0	0	0	0	OR2M3	olfactory receptor family 2 subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:8269]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000228253	1085.338	1290.415	996.502	1299.837	1224.274	1120.987	4660	5569	3160	4134	4441	3502	MT-ATP8	mitochondrially encoded ATP synthase membrane subunit 8 [Source:HGNC Symbol;Acc:HGNC:7415]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02125;K02125;K02125;K02125;K02125;K02125;K02125;K02125;K02125;K02125;K02125	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0005515//protein binding;GO:0015078//proton transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000228278	0	0	0	0	0	0	0	0	0	0	0	0	ORM2	orosomucoid 2 [Source:HGNC Symbol;Acc:HGNC:8499]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0035578//azurophil granule lumen;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	-	GO:0002682//regulation of immune system process;GO:0006953//acute-phase response;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032732//positive regulation of interleukin-1 production;GO:0032760//positive regulation of tumor necrosis factor production	--
ENSG00000228300	19.19	20.608	21.281	25.346	21.763	18.245	313	331	260	313	301	216	FAM174C	family with sequence similarity 174 member C [Source:HGNC Symbol;Acc:HGNC:26073]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000228325	0	0	0	0	0	0	0	0	0	0	0	0	IGKV3D-7	immunoglobulin kappa variable 3D-7 [Source:HGNC Symbol;Acc:HGNC:5829]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000228336	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000228474	95.705	105.058	93.883	119.953	91.969	90.226	880	969.85	637	816.92	714	604	OST4	"oligosaccharyltransferase complex subunit 4, non-catalytic [Source:HGNC Symbol;Acc:HGNC:32483]"	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine	--
ENSG00000228486	0.279	0.295	0.473	0.08	0.419	0.6	4	4	5	1	5	6	C2orf92	chromosome 2 open reading frame 92 [Source:HGNC Symbol;Acc:HGNC:49272]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000228517	0	0	0	0	0	0	0	0	0	0	0	0	CT47A7	cancer/testis antigen family 47 member A7 [Source:HGNC Symbol;Acc:HGNC:33288]	-	-	-	-	-	-	-	--
ENSG00000228567	0	0	0	0	0	0	0	0	0	0	0	0	VN1R4	vomeronasal 1 receptor 4 [Source:HGNC Symbol;Acc:HGNC:19871]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0016503//pheromone receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0019236//response to pheromone	--
ENSG00000228570	1.852	1.984	1.778	1.687	1.972	1.655	239.26	256.57	170.37	162.12	216.19	156.27	NUTM2E	NUT family member 2E [Source:HGNC Symbol;Acc:HGNC:23448]	-	-	-	-	-	-	-	--
ENSG00000228594	4.199	6.165	7.314	8.182	7.496	6.551	185	273	238	267	279	210	FNDC10	fibronectin type III domain containing 10 [Source:HGNC Symbol;Acc:HGNC:42951]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000228607	0	0	0	0	0	0	0	0	0	0	0	0	CLDN25	claudin 25 [Source:HGNC Symbol;Acc:HGNC:37218]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0070160//tight junction	GO:0005198//structural molecule activity	GO:0007155//cell adhesion;GO:0070830//bicellular tight junction assembly	--
ENSG00000228672	0.118	0.096	0.231	0.13	0.038	0.206	11	9	16	9	3	14	PROB1	proline rich basic protein 1 [Source:HGNC Symbol;Acc:HGNC:41906]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000228696	3.055	4.22	2.236	4.383	4.224	3.363	191.77	155.44	82.8	123.66	157.09	130.34	ARL17B	ADP ribosylation factor like GTPase 17B [Source:HGNC Symbol;Acc:HGNC:32387]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000228716	18.587	15.268	15.294	11.149	11.199	12.084	1112.73	1000.32	733.81	500.56	609.27	570.64	DHFR	dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Drug resistance: antineoplastic;Metabolism of cofactors and vitamins;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko01523//Antifolate resistance;ko00790//Folate biosynthesis;ko00670//One carbon pool by folate	K00287;K00287;K00287;K00287	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	"GO:0000900//translation repressor activity, mRNA regulatory element binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0004146//dihydrofolate reductase activity;GO:0005515//protein binding;GO:0005542//folic acid binding;GO:0016491//oxidoreductase activity;GO:0050661//NADP binding;GO:0070402//NADPH binding;GO:1990825//sequence-specific mRNA binding"	GO:0006545//glycine biosynthetic process;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0017148//negative regulation of translation;GO:0031103//axon regeneration;GO:0031427//response to methotrexate;GO:0046452//dihydrofolate metabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0046655//folic acid metabolic process;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:2000121//regulation of removal of superoxide radicals	--
ENSG00000228727	0.768	0.749	0.854	1.248	0.535	0.788	14.59	14.3	11.98	17.56	8.58	10.9	SAPCD1	suppressor APC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13938]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000228789	0.064	0	0	0	0	0	1	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000228836	0	0	0	0	0	0	0	0	0	0	0	0	CT45A5	cancer/testis antigen family 45 member A5 [Source:HGNC Symbol;Acc:HGNC:33270]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000228856	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L30	ubiquitin specific peptidase 17 like family member 30 [Source:HGNC Symbol;Acc:HGNC:44458]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000228927	0	0	0	0	0	0	0	0	0	0	0	0	TSPY3	testis specific protein Y-linked 3 [Source:HGNC Symbol;Acc:HGNC:33876]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation	--
ENSG00000228985	0	0	0	0	0	0	0	0	0	0	0	0	TRDD3	T cell receptor delta diversity 3 [Source:HGNC Symbol;Acc:HGNC:12256]	-	-	-	-	-	-	-	--
ENSG00000229117	1183.986	1265.603	1192.942	1270.633	978.947	1019.35	11660	12526	8681	9269	8150	7300	RPL41	ribosomal protein L41 [Source:HGNC Symbol;Acc:HGNC:10354]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02928;K02928	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000229183	0	0.069	0.094	0	0.165	0	0	2	2	0	4	0	PGA4	pepsinogen A4 [Source:HGNC Symbol;Acc:HGNC:8886]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K06002	GO:0005576//extracellular region;GO:0070062//extracellular exosome;GO:0097486//multivesicular body lumen	GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007586//digestion;GO:0019538//protein metabolic process	--
ENSG00000229292	0	0	0	0	0	0	0	0	0	0	0	0	RFPL4AL1	ret finger protein like 4A like 1 [Source:HGNC Symbol;Acc:HGNC:45147]	-	-	-	-	GO:0000785//chromatin;GO:0005654//nucleoplasm	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0016567//protein ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000229314	0	0	0	0	0.075	0	0	0	0	0	1	0	ORM1	orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0035580//specific granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:1904724//tertiary granule lumen	GO:0005515//protein binding	GO:0002682//regulation of immune system process;GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0032715//negative regulation of interleukin-6 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032732//positive regulation of interleukin-1 production;GO:0032760//positive regulation of tumor necrosis factor production	--
ENSG00000229453	0	0	0	0	0	0	0	0	0	0	0	0	SPINK8	serine peptidase inhibitor Kazal type 8 (putative) [Source:HGNC Symbol;Acc:HGNC:33160]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000229474	0.08	0.395	0.1	0.757	0.447	0.976	4	10	3	17	9	12	PATL2	PAT1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:33630]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0010607//negative regulation of cytoplasmic mRNA processing body assembly;GO:0017148//negative regulation of translation;GO:0033962//P-body assembly	--
ENSG00000229544	0.27	0.105	0.102	0.061	0.089	0.227	18	7	5	3	5	11	NKX1-2	NK1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:31652]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	Homeobox
ENSG00000229549	0	0	0	0	0	0	0	0	0	0	0	0	TSPY8	testis specific protein Y-linked 8 [Source:HGNC Symbol;Acc:HGNC:37471]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation	--
ENSG00000229571	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF25	PRAME family member 25 [Source:HGNC Symbol;Acc:HGNC:49179]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000229579	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L26	ubiquitin specific peptidase 17 like family member 26 [Source:HGNC Symbol;Acc:HGNC:44454]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000229637	0	0	0	0	0	0	0	0	0	0	0	0	PRAC2	PRAC2 small nuclear protein [Source:HGNC Symbol;Acc:HGNC:30143]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000229665	0	0	0	0	0	0	0	0	0	0	0	0	PRR20C	proline rich 20C [Source:HGNC Symbol;Acc:HGNC:37221]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000229674	0	0	0	0	0	0	0	0	0	0	0	0	H2AL3	H2A.L variant histone 3 [Source:HGNC Symbol;Acc:HGNC:53960]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000229676	0	0	0	0	0	0	0	0	0	0	0	0	ZNF492	zinc finger protein 492 [Source:HGNC Symbol;Acc:HGNC:23707]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000229809	5.426	5.807	3.892	5.064	5.887	5.028	114	121	67	78	98	79	ZNF688	zinc finger protein 688 [Source:HGNC Symbol;Acc:HGNC:30489]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000229833	6.921	7.509	9.755	6.676	4.621	6.016	69	95	84	68	49	58	PET100	PET100 cytochrome c oxidase chaperone [Source:HGNC Symbol;Acc:HGNC:40038]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0051082//unfolded protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000229859	0	0	0	0	0	0	0	0	0	0	0	0	PGA3	pepsinogen A3 [Source:HGNC Symbol;Acc:HGNC:8885]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K06002	GO:0005576//extracellular region;GO:0070062//extracellular exosome;GO:0097486//multivesicular body lumen	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000229894	0.129	0.052	0	0.035	0.031	0.213	5	2.02	0	1	1	6	GK3P	glycerol kinase 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:4292]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko03320//PPAR signaling pathway;ko00561//Glycerolipid metabolism	K00864;K00864;K00864	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0004370//glycerol kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor"	GO:0005975//carbohydrate metabolic process;GO:0006071//glycerol metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006641//triglyceride metabolic process;GO:0016310//phosphorylation;GO:0019563//glycerol catabolic process;GO:0046167//glycerol-3-phosphate biosynthetic process	--
ENSG00000229924	0.019	0	0	0	0	0	1	0	0	0	0	0	FAM90A26	family with sequence similarity 90 member A26 [Source:HGNC Symbol;Acc:HGNC:43746]	-	-	-	-	-	-	-	--
ENSG00000229937	0	0	0	0	0	0	0	0	0	0	0	0	PRPS1L1	phosphoribosyl pyrophosphate synthetase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:9463]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Global and overview maps;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00030//Pentose phosphate pathway	K00948;K00948;K00948;K00948;K00948	GO:0002189//ribose phosphate diphosphokinase complex;GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding	GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0008584//male gonad development;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation;GO:0044249//cellular biosynthetic process	--
ENSG00000229972	0	0	0	0	0	0	0	0	0	0	0	0	IQCF3	IQ motif containing F3 [Source:HGNC Symbol;Acc:HGNC:31816]	-	-	-	-	-	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000230031	0	0	0	0	0	0	0	0	0	0	0	0	POTEB2	POTE ankyrin domain family member B2 [Source:HGNC Symbol;Acc:HGNC:48327]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230054	0	0	0	0	0	0	0	0	0	0	0	0	TEX53	testis expressed 53 [Source:HGNC Symbol;Acc:HGNC:53655]	-	-	-	-	-	-	-	--
ENSG00000230062	0	0.036	0.049	0.098	0.022	0	0	1	1	2	1	0	ANKRD66	ankyrin repeat domain 66 [Source:HGNC Symbol;Acc:HGNC:44669]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230124	13.725	13.615	14.766	13.096	13.71	14.556	437.19	441.61	352.29	320.3	373.11	337.63	ACBD6	acyl-CoA binding domain containing 6 [Source:HGNC Symbol;Acc:HGNC:23339]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0008289//lipid binding	-	--
ENSG00000230178	0	0	0	0	0	0	0	0	0	0	0	0	OR4F3	olfactory receptor family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:8300]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000230268	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P8	SSU72 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:43627]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000230301	0	0	0	0	0	0	0	0	0	0	0	0	OR5H6	olfactory receptor family 5 subfamily H member 6 [Source:HGNC Symbol;Acc:HGNC:14767]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000230347	0	0	0	0	0	0	0	0	0	0	0	0	CT47A8	cancer/testis antigen family 47 member A8 [Source:HGNC Symbol;Acc:HGNC:33289]	-	-	-	-	-	-	-	--
ENSG00000230358	0.132	0	0	0	0.024	0.028	8.98	0	0	0	1.4	1.38	SPDYE21	speedy/RINGO cell cycle regulator family member E21 [Source:HGNC Symbol;Acc:HGNC:51517]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000230430	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L25	ubiquitin specific peptidase 17 like family member 25 [Source:HGNC Symbol;Acc:HGNC:44452]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000230453	0.023	0.023	0.11	0.063	0	0.016	2	2	7	4	0	1	ANKRD18B	ankyrin repeat domain 18B [Source:HGNC Symbol;Acc:HGNC:23644]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230522	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L2	methyl-CpG binding domain protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:18532]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230549	0	0.03	0	0	0.036	0	0	1	0	0	1	0	USP17L1	ubiquitin specific peptidase 17 like family member 1 [Source:HGNC Symbol;Acc:HGNC:37182]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000230561	0	0	0	0	0	0	0	0	0	0	0	0	CCDC192	coiled-coil domain containing 192 [Source:HGNC Symbol;Acc:HGNC:49566]	-	-	-	-	-	-	-	--
ENSG00000230594	0	0	0	0	0	0	0	0	0	0	0	0	CT47A4	cancer/testis antigen family 47 member A4 [Source:HGNC Symbol;Acc:HGNC:33285]	-	-	-	-	-	-	-	--
ENSG00000230601	0	0	0	0	0	0	0	0	0	0	0	0	TEX48	testis expressed 48 [Source:HGNC Symbol;Acc:HGNC:52393]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230626	0	0	0	0	0	0	0	0	0	0	0	0	MAP2K2	novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Signal transduction;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Signal transduction;Cancer: overview;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Endocrine and metabolic disease;Endocrine system;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Signal transduction;Endocrine system;Immune system;Signal transduction;Circulatory system;Endocrine system;Endocrine system;Nervous system;Signal transduction;Endocrine system;Signal transduction;Immune system;Immune system;Cancer: overview;Endocrine system;Cancer: specific types;Drug resistance: antineoplastic;Cancer: overview;Endocrine system;Cancer: specific types;Cellular community - eukaryotes;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Cancer: specific types;Nervous system;Endocrine system;Signal transduction;Cancer: specific types;Nervous system;Cancer: specific types;Cancer: specific types	"ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko05164//Influenza A;ko04022//cGMP-PKG signaling pathway;ko05206//MicroRNAs in cancer;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04934//Cushing syndrome;ko04921//Oxytocin signaling pathway;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko04371//Apelin signaling pathway;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04270//Vascular smooth muscle contraction;ko04926//Relaxin signaling pathway;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04660//T cell receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04916//Melanogenesis;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04912//GnRH signaling pathway;ko05210//Colorectal cancer;ko04540//Gap junction;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko05221//Acute myeloid leukemia;ko04720//Long-term potentiation;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko05213//Endometrial cancer;ko04730//Long-term depression;ko05219//Bladder cancer;ko05216//Thyroid cancer"	K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369;K04369	-	GO:0004672//protein kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation	--
ENSG00000230657	0	0	0	0	0	0	0	0	0	0	0	0	PRB4	proline rich protein BstNI subfamily 4 [Source:HGNC Symbol;Acc:HGNC:9340]	-	-	-	-	-	-	-	--
ENSG00000230667	0	0	0	0	0	0	0	0	0	0	0	0	SETSIP	SET like protein [Source:HGNC Symbol;Acc:HGNC:42937]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005811//lipid droplet	GO:0003682//chromatin binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0030154//cell differentiation;GO:0045446//endothelial cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II	--
ENSG00000230707	0.156	0.233	0.159	0.422	0.092	0.161	4	6	3	8	2	3	C16orf72	novel protein (LOC389895)	-	-	-	-	-	-	-	--
ENSG00000230778	0	0	0	0	0	0.014	0	0	0	0	0	1	ANKRD63	ankyrin repeat domain 63 [Source:HGNC Symbol;Acc:HGNC:40027]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000230797	0.385	0.209	0.237	0.284	0.394	0.192	22	12	10	12	19	8	YY2	YY2 transcription factor [Source:HGNC Symbol;Acc:HGNC:31684]	-	-	-	-	GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0031519//PcG protein complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000230873	0.628	0.25	0.158	0	0.26	0.173	20	8	3	0	7	4	STMND1	stathmin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:44668]	-	-	-	-	GO:0005737//cytoplasm;GO:0043005//neuron projection	GO:0015631//tubulin binding	GO:0007019//microtubule depolymerization;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031175//neuron projection development	--
ENSG00000230989	46.114	43.693	46.641	37.436	34.915	42.366	3448	3287	2575	2124	2352	2305	HSBP1	heat shock factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:5203]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:1904115//axon cytoplasm	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006936//muscle contraction;GO:0019896//axonal transport of mitochondrion;GO:0035987//endodermal cell differentiation;GO:0070370//cellular heat acclimation	--
ENSG00000231051	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L28	ubiquitin specific peptidase 17 like family member 28 [Source:HGNC Symbol;Acc:HGNC:44456]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000231068	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP21-3	keratin associated protein 21-3 [Source:HGNC Symbol;Acc:HGNC:34216]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000231192	0	0	0	0	0	0	0	0	0	0	0	0	OR5H1	olfactory receptor family 5 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8346]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000231213	0	0	0	0	0	0	0	0	0	0	0	0	PLSCR5	phospholipid scramblase family member 5 [Source:HGNC Symbol;Acc:HGNC:19952]	-	-	-	-	GO:0005886//plasma membrane	GO:0017128//phospholipid scramblase activity	GO:0017121//plasma membrane phospholipid scrambling	--
ENSG00000231256	0	0.026	0	0	0	0	0	2	0	0	0	0	CFAP97D1	CFAP97 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37241]	-	-	-	-	-	GO:0005515//protein binding	GO:0007288//sperm axoneme assembly	--
ENSG00000231274	0	0	0	0	0	0	0	0	0	0	0	0	SBK3	SH3 domain binding kinase family member 3 [Source:HGNC Symbol;Acc:HGNC:44121]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000231292	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1OR2-108	immunoglobulin kappa variable 1/OR2-108 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5767]	-	-	-	-	GO:0005615//extracellular space	-	GO:0006955//immune response	--
ENSG00000231389	0.42	0.118	0.662	0.157	1.318	0.623	9	3	14	4	29	10	HLA-DPA1	"major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity;GO:0042605//peptide antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0032729//positive regulation of interferon-gamma production;GO:0042102//positive regulation of T cell proliferation;GO:0050870//positive regulation of T cell activation;GO:0071346//cellular response to interferon-gamma	--
ENSG00000231396	0	0	0	0	0	0	0	0	0	0	0	0	USP17L10	ubiquitin specific peptidase 17 like family member 10 [Source:HGNC Symbol;Acc:HGNC:44438]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000231475	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4-31	immunoglobulin heavy variable 4-31 [Source:HGNC Symbol;Acc:HGNC:5649]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000231500	644.03	669.524	670.317	762.924	576.177	599.407	7337	7664	5639	6437	5544	4968	RPS18	ribosomal protein S18 [Source:HGNC Symbol;Acc:HGNC:10401]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02964;K02964	GO:0005581//collagen trimer;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0015935//small ribosomal subunit;GO:0016020//membrane;GO:0022626//cytosolic ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular exosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000231637	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L29	ubiquitin specific peptidase 17 like family member 29 [Source:HGNC Symbol;Acc:HGNC:44457]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000231738	0.284	0.565	0.589	0.448	0.279	0.437	6	12	6	7	3	6	TSPAN19	tetraspanin 19 [Source:HGNC Symbol;Acc:HGNC:31886]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000231767	0.092	0	0.125	0	0	0.127	1	0	1	0	0	1	RPS27AP5	ribosomal protein S27a pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:36867]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Cellular Processes	"Neurodegenerative disease;Infectious disease: viral;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Folding, sorting and degradation;Translation;Transport and catabolism"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05171//Coronavirus disease - COVID-19;ko05012//Parkinson disease;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04120//Ubiquitin mediated proteolysis;ko03010//Ribosome;ko04137//Mitophagy - animal	K02977;K02977;K02977;K02977;K02977;K02977;K02977;K02977	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0031386//protein tag;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding	GO:0006412//translation;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process	--
ENSG00000231824	0	0	0	0	0	0	0	0	0	0	0	0	AKAIN1	A-kinase anchor inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:28285]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding;GO:0051018//protein kinase A binding	GO:0008104//protein localization;GO:0031333//negative regulation of protein-containing complex assembly	--
ENSG00000231852	0.264	0.492	0.58	0.714	0.392	0.462	11	14	17	22	11	14	CYP21A2	cytochrome P450 family 21 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:2600]	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Endocrine system;Lipid metabolism	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko04925//Aldosterone synthesis and secretion;ko04927//Cortisol synthesis and secretion;ko00140//Steroid hormone biosynthesis	K00513;K00513;K00513;K00513;K00513	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0004509//steroid 21-monooxygenase activity;GO:0005496//steroid binding;GO:0005506//iron ion binding;GO:0008289//lipid binding;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0103069//17-hydroxyprogesterone 21-hydroxylase activity;GO:0106309//progesterone 21-hydroxylase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0008202//steroid metabolic process;GO:0016125//sterol metabolic process	--
ENSG00000231861	0	0	0	0	0	0.139	0	0	0	0	0	2	OR5K2	olfactory receptor family 5 subfamily K member 2 [Source:HGNC Symbol;Acc:HGNC:14774]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000231887	0.068	0	0.115	0.091	0.368	0	1	0	1.25	1	4.59	0	PRH1	proline rich protein HaeIII subfamily 1 [Source:HGNC Symbol;Acc:HGNC:9366]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13910	-	-	-	--
ENSG00000231924	0	0	0	0	0	0	0	0	0	0	0	0	PSG1	pregnancy specific beta-1-glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:9514]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	GO:0007565//female pregnancy	--
ENSG00000231925	20.706	22.086	20.978	20.328	19.873	20.987	1288	1365	1001	967	1081.96	1002	TAPBP	TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko04612//Antigen processing and presentation	K08058;K08058;K08058;K08058;K08058	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042824//MHC class I peptide loading complex;GO:0061779//Tapasin-ERp57 complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0015433//ABC-type peptide antigen transporter activity;GO:0042288//MHC class I protein binding;GO:0042605//peptide antigen binding;GO:0046978//TAP1 binding;GO:0046979//TAP2 binding;GO:0051082//unfolded protein binding;GO:0062061//TAP complex binding	"GO:0002397//MHC class I protein complex assembly;GO:0002398//MHC class Ib protein complex assembly;GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006955//immune response;GO:0010468//regulation of gene expression;GO:0015833//peptide transport;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0050776//regulation of immune response;GO:0050823//peptide antigen stabilization;GO:0061635//regulation of protein complex stability;GO:0065003//protein-containing complex assembly"	--
ENSG00000231989	0	0	0	0	0	0	0	0	0	0	0	0	PPP1R2B	PPP1R2 family member B [Source:HGNC Symbol;Acc:HGNC:16318]	-	-	-	-	-	GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0009966//regulation of signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0043666//regulation of phosphoprotein phosphatase activity	--
ENSG00000232030	0	0	0	0	0	0	0	0	0	0	0	0	MAGEB6B	MAGE family member B6B [Source:HGNC Symbol;Acc:HGNC:28824]	-	-	-	-	GO:0005634//nucleus	-	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000232040	1.04	0.873	1.111	0.713	0.731	0.782	128	108	101	65	76	70	ZBED9	zinc finger BED-type containing 9 [Source:HGNC Symbol;Acc:HGNC:13851]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding	GO:0015074//DNA integration;GO:0045787//positive regulation of cell cycle;GO:0050679//positive regulation of epithelial cell proliferation	--
ENSG00000232070	0.283	0.262	0.489	0.053	0.185	0.169	8	7.49	11.05	1	4	3.16	TMEM253	transmembrane protein 253 [Source:HGNC Symbol;Acc:HGNC:32545]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000232112	68.149	68.313	70.164	78.776	57.777	79.253	793	799	603	679	568	671	TMA7	translation machinery associated 7 homolog [Source:HGNC Symbol;Acc:HGNC:26932]	-	-	-	-	-	-	-	--
ENSG00000232113	0	0	0	0	0	0	0	0	0	0	0	0	TEX50	testis expressed 50 [Source:HGNC Symbol;Acc:HGNC:52382]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000232119	5.86	6.258	5.566	6.111	4.85	4.703	406	364	262	278	255	261	MCTS1	MCTS1 re-initiation and release factor [Source:HGNC Symbol;Acc:HGNC:23357]	-	-	-	-	GO:0005737//cytoplasm;GO:0022627//cytosolic small ribosomal subunit	GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding	GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0032790//ribosome disassembly;GO:0040008//regulation of growth;GO:0075522//IRES-dependent viral translational initiation	--
ENSG00000232125	0	0	0	0	0	0	0	0	0	0	0	0	DYTN	dystrotelin [Source:HGNC Symbol;Acc:HGNC:23279]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045202//synapse	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0099536//synaptic signaling	--
ENSG00000232196	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L4	MT-RNR2 like 4 [Source:HGNC Symbol;Acc:HGNC:37161]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000232216	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-43	immunoglobulin heavy variable 3-43 [Source:HGNC Symbol;Acc:HGNC:5604]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000232237	0.024	0.024	0	0	0	0	1	1	0	0	0	0	ASCL5	achaete-scute family bHLH transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:33169]	-	-	-	-	-	GO:0003700//DNA-binding transcription factor activity;GO:0046983//protein dimerization activity	GO:0006357//regulation of transcription by RNA polymerase II	bHLH
ENSG00000232258	0	0	0	0	0	0	0	0	0	0	0	0	TMEM114	transmembrane protein 114 [Source:HGNC Symbol;Acc:HGNC:33227]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane	GO:0005515//protein binding	-	--
ENSG00000232263	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP25-1	keratin associated protein 25-1 [Source:HGNC Symbol;Acc:HGNC:34003]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000232264	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L24	ubiquitin specific peptidase 17 like family member 24 [Source:HGNC Symbol;Acc:HGNC:44453]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000232268	0	0	0	0	0	0	0	0	0	0	0	0	OR52I1	olfactory receptor family 52 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:15220]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000232382	0	0	0	0	0	0	0	0	0	0	0	0	OR5K1	olfactory receptor family 5 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:8349]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000232388	19.852	20.407	20.814	26.91	21.8	27.393	226	232.24	173	222.79	208	223	SMIM26	small integral membrane protein 26 [Source:HGNC Symbol;Acc:HGNC:43430]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000232399	0	0	0	0	0	0	0	0	0	0	0	0	USP17L13	ubiquitin specific peptidase 17 like family member 13 [Source:HGNC Symbol;Acc:HGNC:44441]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000232423	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF6	PRAME family member 6 [Source:HGNC Symbol;Acc:HGNC:30583]	-	-	-	-	GO:0005737//cytoplasm;GO:0031462//Cul2-RING ubiquitin ligase complex	GO:1990756//ubiquitin ligase-substrate adaptor activity	"GO:0008284//positive regulation of cell population proliferation;GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000232434	0.841	0.661	0.591	0.463	0.652	0.557	81	64	42	33	53	39	AJM1	apical junction component 1 homolog [Source:HGNC Symbol;Acc:HGNC:37284]	-	-	-	-	GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005929//cilium;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0043296//apical junction complex	-	GO:0045216//cell-cell junction organization	--
ENSG00000232535	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000232543	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000232593	0.011	0.045	0.031	0.031	0.067	0.016	1	4	2	2	5	1	KANTR	KDM5C adjacent transcript [Source:HGNC Symbol;Acc:HGNC:49510]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000232629	0	0	0	0	0.079	0	0	0	0	0	1	0	HLA-DQB2	"major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:HGNC:4945]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000232653	1.438	1.332	1.587	1.35	1.238	0.762	158.96	147.94	129.59	110.54	115.63	60.06	GOLGA8N	golgin A8 family member N [Source:HGNC Symbol;Acc:HGNC:44405]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000232810	0	0	0	0	0	0	0	0	0	0	0	0	TNF	tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Signaling molecules and interaction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Immune disease;Infectious disease: bacterial;Cancer: overview;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Immune system;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Infectious disease: viral;Immune disease;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Immune system;Development and regeneration;Signal transduction;Signal transduction;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Immune disease;Infectious disease: parasitic;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Endocrine and metabolic disease;Signaling molecules and interaction;Immune system;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Immune system;Immune system;Endocrine system;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic;Endocrine and metabolic disease;Endocrine and metabolic disease;Immune disease;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04640//Hematopoietic cell lineage;ko04932//Non-alcoholic fatty liver disease;ko04217//Necroptosis;ko05414//Dilated cardiomyopathy;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko05160//Hepatitis C;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04664//Fc epsilon RI signaling pathway;ko04380//Osteoclast differentiation;ko04071//Sphingolipid signaling pathway;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko05310//Asthma;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04657//IL-17 signaling pathway;ko04350//TGF-beta signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko05133//Pertussis;ko04612//Antigen processing and presentation;ko04622//RIG-I-like receptor signaling pathway;ko04920//Adipocytokine signaling pathway;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko05144//Malaria;ko04930//Type II diabetes mellitus;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease;ko01523//Antifolate resistance	K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156;K03156	GO:0001891//phagocytic cup;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0045121//membrane raft;GO:0055037//recycling endosome	GO:0000976//transcription cis-regulatory region binding;GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0000165//MAPK cascade;GO:0001666//response to hypoxia;GO:0001774//microglial cell activation;GO:0001775//cell activation;GO:0001819//positive regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002037//negative regulation of L-glutamate import across plasma membrane;GO:0002439//chronic inflammatory response to antigenic stimulus;GO:0002523//leukocyte migration involved in inflammatory response;GO:0002526//acute inflammatory response;GO:0002637//regulation of immunoglobulin production;GO:0002719//negative regulation of cytokine production involved in immune response;GO:0002876//positive regulation of chronic inflammatory response to antigenic stimulus;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0003009//skeletal muscle contraction;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0006006//glucose metabolic process;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0007254//JNK cascade;GO:0007623//circadian rhythm;GO:0008285//negative regulation of cell population proliferation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009314//response to radiation;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009615//response to virus;GO:0009617//response to bacterium;GO:0009651//response to salt stress;GO:0009887//animal organ morphogenesis;GO:0010033//response to organic substance;GO:0010459//negative regulation of heart rate;GO:0010573//vascular endothelial growth factor production;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0010888//negative regulation of lipid storage;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0019722//calcium-mediated signaling;GO:0030198//extracellular matrix organization;GO:0030316//osteoclast differentiation;GO:0030730//sequestering of triglyceride;GO:0030866//cortical actin cytoskeleton organization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0031622//positive regulation of fever generation;GO:0031642//negative regulation of myelination;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0031667//response to nutrient levels;GO:0032496//response to lipopolysaccharide;GO:0032715//negative regulation of interleukin-6 production;GO:0032722//positive regulation of chemokine production;GO:0032724//positive regulation of fractalkine production;GO:0032729//positive regulation of interferon-gamma production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032741//positive regulation of interleukin-18 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0034138//toll-like receptor 3 signaling pathway;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0042127//regulation of cell population proliferation;GO:0042311//vasodilation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042742//defense response to bacterium;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043068//positive regulation of programmed cell death;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043242//negative regulation of protein-containing complex disassembly;GO:0043243//positive regulation of protein-containing complex disassembly;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0043491//protein kinase B signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0043525//positive regulation of neuron apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045071//negative regulation of viral genome replication;GO:0045123//cellular extravasation;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045471//response to ethanol;GO:0045598//regulation of fat cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045670//regulation of osteoclast differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0045760//positive regulation of action potential;GO:0045785//positive regulation of cell adhesion;GO:0045840//positive regulation of mitotic nuclear division;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045930//negative regulation of mitotic cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045994//positive regulation of translational initiation by iron;GO:0046325//negative regulation of glucose import;GO:0046330//positive regulation of JNK cascade;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048143//astrocyte activation;GO:0048566//embryonic digestive tract development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050708//regulation of protein secretion;GO:0050727//regulation of inflammatory response;GO:0050729//positive regulation of inflammatory response;GO:0050766//positive regulation of phagocytosis;GO:0050768//negative regulation of neurogenesis;GO:0050793//regulation of developmental process;GO:0050796//regulation of insulin secretion;GO:0050806//positive regulation of synaptic transmission;GO:0050807//regulation of synapse organization;GO:0050830//defense response to Gram-positive bacterium;GO:0050890//cognition;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0050995//negative regulation of lipid catabolic process;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0051046//regulation of secretion;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051173//positive regulation of nitrogen compound metabolic process;GO:0051222//positive regulation of protein transport;GO:0051384//response to glucocorticoid;GO:0051798//positive regulation of hair follicle development;GO:0051897//positive regulation of protein kinase B signaling;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0060252//positive regulation of glial cell proliferation;GO:0060557//positive regulation of vitamin D biosynthetic process;GO:0060559//positive regulation of calcidiol 1-monooxygenase activity;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060693//regulation of branching involved in salivary gland morphogenesis;GO:0061044//negative regulation of vascular wound healing;GO:0061048//negative regulation of branching involved in lung morphogenesis;GO:0065008//regulation of biological quality;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071219//cellular response to molecule of bacterial origin;GO:0071222//cellular response to lipopolysaccharide;GO:0071230//cellular response to amino acid stimulus;GO:0071300//cellular response to retinoic acid;GO:0071316//cellular response to nicotine;GO:0071346//cellular response to interferon-gamma;GO:0071407//cellular response to organic cyclic compound;GO:0071677//positive regulation of mononuclear cell migration;GO:0071803//positive regulation of podosome assembly;GO:0072577//endothelial cell apoptotic process;GO:0072659//protein localization to plasma membrane;GO:0090324//negative regulation of oxidative phosphorylation;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097237//cellular response to toxic substance;GO:0097421//liver regeneration;GO:0097527//necroptotic signaling pathway;GO:0120190//negative regulation of bile acid secretion;GO:0140460//response to Gram-negative bacterium;GO:0150078//positive regulation of neuroinflammatory response;GO:0150129//positive regulation of interleukin-33 production;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:1900222//negative regulation of amyloid-beta clearance;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901554//response to paracetamol;GO:1901647//positive regulation of synoviocyte proliferation;GO:1901671//positive regulation of superoxide dismutase activity;GO:1902004//positive regulation of amyloid-beta formation;GO:1902565//positive regulation of neutrophil activation;GO:1902895//positive regulation of pri-miRNA transcription by RNA polymerase II;GO:1903078//positive regulation of protein localization to plasma membrane;GO:1903140//regulation of establishment of endothelial barrier;GO:1903223//positive regulation of oxidative stress-induced neuron death;GO:1903347//negative regulation of bicellular tight junction assembly;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:1904646//cellular response to amyloid-beta;GO:1904707//positive regulation of vascular associated smooth muscle cell proliferation;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:1904999//positive regulation of leukocyte adhesion to arterial endothelial cell;GO:1905242//response to 3,3',5-triiodo-L-thyronine;GO:1990268//response to gold nanoparticle;GO:2000010//positive regulation of protein localization to cell surface;GO:2000272//negative regulation of signaling receptor activity;GO:2000334//positive regulation of blood microparticle formation;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:2000347//positive regulation of hepatocyte proliferation;GO:2000351//regulation of endothelial cell apoptotic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:2001234//negative regulation of apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2001272//positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis"	--
ENSG00000232838	4.65	3.323	2.058	4.995	2.087	3.97	111.01	79.74	36.28	88.34	42.1	68.97	PET117	PET117 cytochrome c oxidase chaperone [Source:HGNC Symbol;Acc:HGNC:40045]	-	-	-	-	GO:0005739//mitochondrion	-	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000232859	3.966	6.105	4.857	5.825	5.305	4.68	117	179	108	127	133	104	LYRM9	LYR motif containing 9 [Source:HGNC Symbol;Acc:HGNC:27314]	-	-	-	-	-	-	-	--
ENSG00000232948	0	0	0	0	0	0	0	0	0	0	0	0	DEFB130A	defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis	--
ENSG00000233024	2.7	11.044	10.505	10.338	9.99	12.314	55.23	259.62	196.3	152.37	182.01	204.97	NPIPA9	"nuclear pore complex interacting protein family, member A9 [Source:HGNC Symbol;Acc:HGNC:41984]"	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000233041	0	0	0	0	0	0	0	0	0	0	0	0	PHGR1	"proline, histidine and glycine rich 1 [Source:HGNC Symbol;Acc:HGNC:37226]"	-	-	-	-	-	-	-	--
ENSG00000233050	0	0	0	0	0	0	0	0	0	0	0	0	DEFB130B	defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0031731//CCR6 chemokine receptor binding;GO:0042056//chemoattractant activity	GO:0006952//defense response;GO:0042742//defense response to bacterium;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis	--
ENSG00000233056	0.017	0.017	0	0	0.082	0.024	1	1	0	0	4	1	ERVH48-1	endogenous retrovirus group 48 member 1 [Source:HGNC Symbol;Acc:HGNC:17216]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane	GO:0005515//protein binding	GO:0006949//syncytium formation	--
ENSG00000233087	0.042	0.03	0.038	0.037	0.051	0.018	3.24	2.27	2.12	2.07	3.3	1	RAB6D	"RAB6D, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30272]"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi"	--
ENSG00000233136	0	0	0	0	0	0	0	0	0	0	0	0	USP17L11	ubiquitin specific peptidase 17 like family member 11 [Source:HGNC Symbol;Acc:HGNC:44439]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000233198	0.061	0	0.125	0.207	0.291	0.127	2	0	3	5	8	3	RNF224	ring finger protein 224 [Source:HGNC Symbol;Acc:HGNC:41912]	-	-	-	-	-	GO:0046872//metal ion binding	-	--
ENSG00000233232	0	0.057	0.037	0	0.121	0.158	0	1.67	0.72	0	2.97	3.01	NPIPB7	nuclear pore complex interacting protein family member B7 [Source:HGNC Symbol;Acc:HGNC:33832]	-	-	-	-	GO:0005576//extracellular region;GO:0005654//nucleoplasm	-	-	--
ENSG00000233276	240.934	271.541	283.116	318.078	277.402	297.561	4495	5082	3898	4393	4370	4036	GPX1	glutathione peroxidase 1 [Source:HGNC Symbol;Acc:HGNC:4553]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Endocrine system;Lipid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04918//Thyroid hormone synthesis;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism	K00432;K00432;K00432;K00432;K00432;K00432;K00432	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0097413//Lewy body	GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0016491//oxidoreductase activity;GO:0017124//SH3 domain binding;GO:0047066//phospholipid-hydroperoxide glutathione peroxidase activity	"GO:0000302//response to reactive oxygen species;GO:0001659//temperature homeostasis;GO:0001885//endothelial cell development;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006749//glutathione metabolic process;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0007568//aging;GO:0007605//sensory perception of sound;GO:0008283//cell population proliferation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0009410//response to xenobiotic stimulus;GO:0009609//response to symbiotic bacterium;GO:0009611//response to wounding;GO:0009636//response to toxic substance;GO:0009650//UV protection;GO:0009725//response to hormone;GO:0009749//response to glucose;GO:0010269//response to selenium ion;GO:0010332//response to gamma radiation;GO:0014070//response to organic cyclic compound;GO:0014902//myotube differentiation;GO:0018158//protein oxidation;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0032355//response to estradiol;GO:0033194//response to hydroperoxide;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0034599//cellular response to oxidative stress;GO:0035094//response to nicotine;GO:0040029//regulation of gene expression, epigenetic;GO:0042311//vasodilation;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043403//skeletal muscle tissue regeneration;GO:0043534//blood vessel endothelial cell migration;GO:0045444//fat cell differentiation;GO:0045454//cell redox homeostasis;GO:0048741//skeletal muscle fiber development;GO:0051402//neuron apoptotic process;GO:0051450//myoblast proliferation;GO:0051593//response to folic acid;GO:0051702//biological process involved in interaction with symbiont;GO:0051897//positive regulation of protein kinase B signaling;GO:0060047//heart contraction;GO:0060055//angiogenesis involved in wound healing;GO:0061136//regulation of proteasomal protein catabolic process;GO:0071333//cellular response to glucose stimulus;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0098869//cellular oxidant detoxification;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1902905//positive regulation of supramolecular fiber organization"	--
ENSG00000233381	1.561	1.68	0.592	0.874	1.142	0.427	62.28	67.37	17.43	25.82	38.48	12.4	AK4P3	adenylate kinase 4 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:21596]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00730//Thiamine metabolism	K00939;K00939;K00939	GO:0005739//mitochondrion	"GO:0004017//adenylate kinase activity;GO:0005524//ATP binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity"	GO:0006139//nucleobase-containing compound metabolic process	--
ENSG00000233412	0	0	0	0	0	0	0	0	0	0	0	0	OR5H15	olfactory receptor family 5 subfamily H member 15 [Source:HGNC Symbol;Acc:HGNC:31287]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000233436	0	0.082	0	0	0	0.023	0	5	0	0	0	1	BTBD18	BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:37214]	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding	GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0010529//negative regulation of transposition;GO:0030154//cell differentiation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:1990511//piRNA biosynthetic process	--
ENSG00000233493	2.497	3.796	3.099	5.713	3.777	3.528	36	55	33	61	46	37	TMEM238	transmembrane protein 238 [Source:HGNC Symbol;Acc:HGNC:40042]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000233608	0	0	0	0.111	0.128	0	0	0	0	2	3	0	TWIST2	twist family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:20670]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K09069	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0032502//developmental process;GO:0043066//negative regulation of apoptotic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	bHLH
ENSG00000233655	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000233670	0	0	0	0	0	0	0	0	0	0	0	0	PIRT	phosphoinositide interacting regulator of transient receptor potential channels [Source:HGNC Symbol;Acc:HGNC:37239]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0044325//transmembrane transporter binding;GO:1902936//phosphatidylinositol bisphosphate binding"	GO:0009408//response to heat;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048266//behavioral response to pain;GO:2001259//positive regulation of cation channel activity	--
ENSG00000233701	0	0	0	0	0	0	0	0	0	0	0	0	PRR23C	proline rich 23C [Source:HGNC Symbol;Acc:HGNC:37173]	-	-	-	-	-	-	-	--
ENSG00000233732	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-10	immunoglobulin heavy variable 3/OR16-10 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5634]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000233757	1.173	1.219	0.706	0.563	0.987	1.325	45	47	20	16	32	37	ZNF286A	novel C2H2 type zinc finger protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000233802	0	0	0	0	0	0	0	0	0	0	0	0	TRIM49D2	tripartite motif containing 49D2 [Source:HGNC Symbol;Acc:HGNC:37217]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000233803	0	0	0	0	0	0	0	0	0	0	0	0	TSPY4	testis specific protein Y-linked 4 [Source:HGNC Symbol;Acc:HGNC:37287]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation	--
ENSG00000233816	0	0	0	0	0	0	0	0	0	0	0	0	IFNA13	interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0051707//response to other organism;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000233822	0.49	0.712	0.781	0.682	0.152	0.861	23	18	11	16	11	14	H2BC15	H2B clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:4749]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000233917	0	0	0	0	0	0	0	0	0	0	0	0	POTEB	POTE ankyrin domain family member B [Source:HGNC Symbol;Acc:HGNC:33734]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000233927	72.638	67.905	75.677	86.6	72.767	75.971	2003.85	1882.91	1541.9	1769.62	1695.96	1524.91	RPS28	ribosomal protein S28 [Source:HGNC Symbol;Acc:HGNC:10418]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02979;K02979	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015935//small ribosomal subunit;GO:0022627//cytosolic small ribosomal subunit;GO:0042788//polysomal ribosome;GO:0070062//extracellular exosome;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0000028//ribosomal small subunit assembly;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing;GO:0006412//translation;GO:0030490//maturation of SSU-rRNA;GO:0042254//ribosome biogenesis;GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000233932	0.036	0.061	0.025	0.025	0.087	0.075	2	4	1	1	4	3	CTXN2	cortexin 2 [Source:HGNC Symbol;Acc:HGNC:31109]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000233954	0.044	0.044	0	0.09	0	0.061	2.01	2.01	0	3.01	0	2.01	UQCRHL	ubiquinol-cytochrome c reductase hinge protein like [Source:HGNC Symbol;Acc:HGNC:51714]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416;K00416	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005750//mitochondrial respiratory chain complex III;GO:0016020//membrane;GO:0070469//respirasome	-	"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c"	--
ENSG00000233999	0	0	0	0	0	0.379	0	0	0	0	0	2	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5830]	-	-	-	-	GO:0005615//extracellular space	-	GO:0006955//immune response	--
ENSG00000234068	0	0	0	0	0	0	0	0	0	0	0	0	PAGE2	PAGE family member 2 [Source:HGNC Symbol;Acc:HGNC:31804]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000234127	21.733	21.971	26.632	29.976	25.898	28.759	1144	1186	1039	1223	1222	1088	TRIM26	tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0002376//immune system process;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0044790//negative regulation by host of viral release from host cell;GO:0045087//innate immune response;GO:0046597//negative regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity	--
ENSG00000234186	0	0	0	0	0	0	0	0	0	0	0	0	C16orf82	chromosome 16 open reading frame 82 [Source:HGNC Symbol;Acc:HGNC:30755]	-	-	-	-	-	-	-	--
ENSG00000234224	0.876	0.67	0.547	0.182	0.452	0.093	39	30	18	6	17	3	TMEM229A	transmembrane protein 229A [Source:HGNC Symbol;Acc:HGNC:37279]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000234278	0	0	0	0	0	0	0	0	0	0	0	0	PRR20E	proline rich 20E [Source:HGNC Symbol;Acc:HGNC:37223]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000234284	1.608	1.209	1.129	1.102	2.028	1.263	96	82	44	43	66	62	ZNF879	zinc finger protein 879 [Source:HGNC Symbol;Acc:HGNC:37273]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000234289	0	0	0	0	0	0	0	0	0	0	0	0	H2BS1	H2B.S histone 1 [Source:HGNC Symbol;Acc:HGNC:4762]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0021762//substantia nigra development;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000234409	0	0	0	0	0	0	0	0	0	0	0	0	CCDC188	coiled-coil domain containing 188 [Source:HGNC Symbol;Acc:HGNC:51899]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000234414	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1A1	RNA binding motif protein Y-linked family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:9912]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000234438	0	0	0	0	0	0	0	0	0	0	0	0	KBTBD13	kelch repeat and BTB domain containing 13 [Source:HGNC Symbol;Acc:HGNC:37227]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0014728//regulation of the force of skeletal muscle contraction;GO:0016567//protein ubiquitination;GO:0090076//relaxation of skeletal muscle	--
ENSG00000234444	0.188	0.198	0.211	0.14	0.332	0.2	35	37	22	19	26	27	ZNF736	zinc finger protein 736 [Source:HGNC Symbol;Acc:HGNC:32467]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000234465	1.756	1.355	1.94	0.478	1.837	2.349	22	17	19	5	19	22	PINLYP	phospholipase A2 inhibitor and LY6/PLAUR domain containing [Source:HGNC Symbol;Acc:HGNC:44206]	-	-	-	-	GO:0005576//extracellular region	GO:0004859//phospholipase inhibitor activity	GO:0043086//negative regulation of catalytic activity	--
ENSG00000234469	0	0.145	0	0	0	0	0	3	0	0	0	0	CLDN34	claudin 34 [Source:HGNC Symbol;Acc:HGNC:51259]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity	GO:0007155//cell adhesion;GO:0070830//bicellular tight junction assembly	--
ENSG00000234511	0	0	0	0	0	0	0	0	0	0	0	0	C5orf58	chromosome 5 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:37272]	-	-	-	-	-	-	-	--
ENSG00000234545	3.436	2.959	2.317	2.523	2.84	3.416	157	146	84	89	114	112	FAM133B	family with sequence similarity 133 member B [Source:HGNC Symbol;Acc:HGNC:28629]	-	-	-	-	-	GO:0003723//RNA binding	-	--
ENSG00000234560	0	0	0	0	0	0	0	0	0	0	0	0	OR10G8	olfactory receptor family 10 subfamily G member 8 [Source:HGNC Symbol;Acc:HGNC:14845]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000234602	7.535	6.554	5.437	2.01	3.365	3.907	334	292	178	66	126	126	MCIDAS	multiciliate differentiation and DNA synthesis associated cell cycle protein [Source:HGNC Symbol;Acc:HGNC:40050]	-	-	-	-	GO:0005634//nucleus;GO:0016604//nuclear body	GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0006275//regulation of DNA replication;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0008156//negative regulation of DNA replication;GO:0030030//cell projection organization;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0044458//motile cilium assembly;GO:0045786//negative regulation of cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060271//cilium assembly;GO:0098534//centriole assembly;GO:1902017//regulation of cilium assembly;GO:1903251//multi-ciliated epithelial cell differentiation"	--
ENSG00000234616	4.418	4.391	4.723	4.956	4.526	5.665	727	724	536	639	685	602	JRK	Jrk helix-turn-helix protein [Source:HGNC Symbol;Acc:HGNC:6199]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0090263//positive regulation of canonical Wnt signaling pathway	--
ENSG00000234719	2.237	2.847	1.965	2.828	2.092	1.934	64.96	77.57	39.83	57.27	48.87	41.55	NPIPB2	nuclear pore complex interacting protein family member B2 [Source:HGNC Symbol;Acc:HGNC:37451]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	-	-	--
ENSG00000234745	254.128	258.131	291.824	341.657	313.167	318.981	8128.91	8298.13	6895.09	8090.64	8468.03	7432.97	HLA-B	"major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932]"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cell growth and death;Signaling molecules and interaction;Cardiovascular disease;Immune disease;Immune disease;Immune system;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko04144//Endocytosis;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04218//Cellular senescence;ko04514//Cell adhesion molecules;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05330//Allograft rejection;ko04612//Antigen processing and presentation;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751;K06751	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0031901//early endosome membrane;GO:0042612//MHC class I protein complex;GO:0055038//recycling endosome membrane;GO:0070062//extracellular exosome;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0046977//TAP binding;GO:0051087//chaperone binding	"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002486//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0002667//regulation of T cell anergy;GO:0006952//defense response;GO:0006955//immune response;GO:0016045//detection of bacterium;GO:0019882//antigen processing and presentation;GO:0032655//regulation of interleukin-12 production;GO:0032675//regulation of interleukin-6 production;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0045087//innate immune response;GO:0045321//leukocyte activation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:2001198//regulation of dendritic cell differentiation"	--
ENSG00000234776	0	0	0	0	0	0	0	0	0	0	0	0	C11orf94	chromosome 11 open reading frame 94 [Source:HGNC Symbol;Acc:HGNC:37213]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000234828	0	0	0	0	0	0	0	0	0	0	0	0	IQCM	IQ motif containing M [Source:HGNC Symbol;Acc:HGNC:53443]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000234829	0	0	0	0	0	0	0	0	0	0	0	0	IFNA17	interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0007165//signal transduction;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000234857	24.06	23.694	27.917	25.545	25.921	25.835	1996.73	1976.43	1711.13	1570.32	1817.41	1560.02	HNRNPUL2-BSCL2	HNRNPUL2-BSCL2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49189]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000234906	0	0	0	0	0.086	0.201	0	0	0	0	1	2	APOC2	apolipoprotein C2 [Source:HGNC Symbol;Acc:HGNC:609]	Organismal Systems	Digestive system	ko04979//Cholesterol metabolism	K22287	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005769//early endosome;GO:0034361//very-low-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle;GO:0034364//high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0042627//chylomicron	GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0016004//phospholipase activator activity;GO:0043274//phospholipase binding;GO:0055102//lipase inhibitor activity;GO:0060230//lipoprotein lipase activator activity	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0010518//positive regulation of phospholipase activity;GO:0010898//positive regulation of triglyceride catabolic process;GO:0010902//positive regulation of very-low-density lipoprotein particle remodeling;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0016042//lipid catabolic process;GO:0032375//negative regulation of cholesterol transport;GO:0033344//cholesterol efflux;GO:0033700//phospholipid efflux;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0034371//chylomicron remodeling;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034382//chylomicron remnant clearance;GO:0034384//high-density lipoprotein particle clearance;GO:0042632//cholesterol homeostasis;GO:0043086//negative regulation of catalytic activity;GO:0043691//reverse cholesterol transport;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045833//negative regulation of lipid metabolic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0050790//regulation of catalytic activity;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0060697//positive regulation of phospholipid catabolic process;GO:0070328//triglyceride homeostasis	--
ENSG00000234965	7.167	8.235	3.652	1.392	1.556	1.236	271	313	102	39	38	34	SHISA8	shisa family member 8 [Source:HGNC Symbol;Acc:HGNC:18351]	-	-	-	-	GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032281//AMPA glutamate receptor complex;GO:0032591//dendritic spine membrane;GO:0045211//postsynaptic membrane	-	GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000235007	0.092	0.048	0	0.048	0.058	0.082	4.16	2.02	0	2.02	2.07	3.05	PTPA	novel protein	Human Diseases;Human Diseases	Cardiovascular disease;Endocrine and metabolic disease	ko05415//Diabetic cardiomyopathy;ko04931//Insulin resistance	K17605;K17605	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016853//isomerase activity;GO:0019211//phosphatase activator activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0050790//regulation of catalytic activity	--
ENSG00000235034	0.317	0.63	1.201	0.721	0.525	0.261	5	10	14	7	7	3	C19orf81	chromosome 19 open reading frame 81 [Source:HGNC Symbol;Acc:HGNC:40041]	-	-	-	-	-	-	-	--
ENSG00000235098	0.123	0.192	0.223	0.278	0.362	0.396	5	8	6	7	12	12	ANKRD65	ankyrin repeat domain 65 [Source:HGNC Symbol;Acc:HGNC:42950]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000235106	17.895	18.648	19.828	18.675	17.206	18.198	1318.09	1300.12	1049.91	951.05	1071.81	953.86	BRD3OS	BRD3 opposite strand [Source:HGNC Symbol;Acc:HGNC:24742]	-	-	-	-	-	-	-	--
ENSG00000235109	2.555	2.737	2.295	3.366	1.899	2.956	145	147	92	96	77	91	ZSCAN31	zinc finger and SCAN domain containing 31 [Source:HGNC Symbol;Acc:HGNC:14097]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000235118	0	0	0	0	0	0	0	0	0	0	0	0	FAM237A	family with sequence similarity 237 member A [Source:HGNC Symbol;Acc:HGNC:52388]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000235162	16.712	14.439	13.387	14.784	11.955	13.585	455	369	269	298	275	269	C12orf75	chromosome 12 open reading frame 75 [Source:HGNC Symbol;Acc:HGNC:35164]	-	-	-	-	-	-	-	--
ENSG00000235169	6.912	3.938	2.45	7.843	6.538	6.518	73	42	20	62	59	51	SMIM1	small integral membrane protein 1 (Vel blood group) [Source:HGNC Symbol;Acc:HGNC:44204]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042803//protein homodimerization activity	-	--
ENSG00000235173	10.123	11.068	11.876	12.188	13.103	12.141	530	540	461	448	567	458	HGH1	HGH1 homolog [Source:HGNC Symbol;Acc:HGNC:24161]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000235194	2.77	2.335	2.229	3.801	3.448	2.56	194	201	139	192	230	154	PPP1R3E	protein phosphatase 1 regulatory subunit 3E [Source:HGNC Symbol;Acc:HGNC:14943]	Organismal Systems;Human Diseases	Endocrine system;Endocrine and metabolic disease	ko04910//Insulin signaling pathway;ko04931//Insulin resistance	K07189;K07189	GO:0000164//protein phosphatase type 1 complex;GO:0042587//glycogen granule	GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding;GO:0050196//[phosphorylase] phosphatase activity;GO:2001069//glycogen binding	GO:0005975//carbohydrate metabolic process;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0006470//protein dephosphorylation;GO:0045725//positive regulation of glycogen biosynthetic process	--
ENSG00000235268	0	0	0	0	0	0	0	0	0	0	0	0	KDM4E	lysine demethylase 4E [Source:HGNC Symbol;Acc:HGNC:37098]	-	-	-	-	GO:0005634//nucleus	GO:0016491//oxidoreductase activity;GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0140684//histone H3-tri/dimethyl-lysine-9 demethylase activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0033169//histone H3-K9 demethylation	--
ENSG00000235272	0	0	0	0	0	0	0	0	0	0	0	0	RAMACL	RNA guanine-7 methyltransferase activating subunit like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:21234]	-	-	-	-	GO:0005845//mRNA cap binding complex;GO:0031533//mRNA cap methyltransferase complex	GO:0003723//RNA binding	GO:0032259//methylation;GO:0036031//recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex;GO:0106005//RNA 5'-cap (guanine-N7)-methylation	--
ENSG00000235376	0	0	0	0	0	0	0	0	0	0	0	0	RPEL1	ribulose-5-phosphate-3-epimerase like 1 [Source:HGNC Symbol;Acc:HGNC:45241]	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00040//Pentose and glucuronate interconversions;ko00030//Pentose phosphate pathway	K01783;K01783;K01783;K01783;K01783	GO:0005829//cytosol	"GO:0003824//catalytic activity;GO:0004750//ribulose-phosphate 3-epimerase activity;GO:0016853//isomerase activity;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0046872//metal ion binding"	"GO:0005975//carbohydrate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019323//pentose catabolic process;GO:0044262//cellular carbohydrate metabolic process"	--
ENSG00000235387	0.031	0.031	0.212	0	0.037	0	1	1	5	0	1	0	SPAAR	small regulatory polypeptide of amino acid response [Source:HGNC Symbol;Acc:HGNC:27244]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0046611//lysosomal proton-transporting V-type ATPase complex;GO:1905103//integral component of lysosomal membrane	-	GO:0043416//regulation of skeletal muscle tissue regeneration;GO:0071230//cellular response to amino acid stimulus;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000235453	5.762	6.468	7.068	7.058	7.212	5.786	80	77	56	54	62	69	SMIM27	small integral membrane protein 27 [Source:HGNC Symbol;Acc:HGNC:31420]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000235568	0.009	0.026	0.047	0	0	0	1	3	4	0	0	0	NFAM1	NFAT activating protein with ITAM motif 1 [Source:HGNC Symbol;Acc:HGNC:29872]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0045121//membrane raft	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0001819//positive regulation of cytokine production;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030183//B cell differentiation;GO:0035556//intracellular signal transduction;GO:0045577//regulation of B cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0051091//positive regulation of DNA-binding transcription factor activity	--
ENSG00000235608	0	0	0	0	0	0	0	0	0	0	0	0	NKX1-1	NK1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:24975]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0008150//biological_process;GO:0010906//regulation of glucose metabolic process;GO:0030154//cell differentiation;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0050877//nervous system process"	Homeobox
ENSG00000235631	0	0	0.052	0.156	0	0	0	0	1	3	0	0	RNF148	ring finger protein 148 [Source:HGNC Symbol;Acc:HGNC:22411]	-	-	-	-	GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination	--
ENSG00000235699	0	0	0	0	0	0	0	0	0	0	0	0	CXorf51B	chromosome X open reading frame 51B [Source:HGNC Symbol;Acc:HGNC:42787]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000235711	0.061	0.035	0.012	0.024	0.062	0.024	7	4	1	2	6	2	ANKRD34C	ankyrin repeat domain 34C [Source:HGNC Symbol;Acc:HGNC:33888]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000235718	198.917	198.081	242.99	228.287	234.405	285.895	12284.08	12524.59	11416.82	10588.44	12158.04	13432.62	MFRP	membrane frizzled-related protein [Source:HGNC Symbol;Acc:HGNC:18121]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007601//visual perception;GO:0009792//embryo development ending in birth or egg hatching;GO:0042462//eye photoreceptor cell development;GO:0060041//retina development in camera-type eye	--
ENSG00000235750	1.222	0.915	1.445	0.78	1.37	1.161	106	73	74	52	107	75	KIAA0040	KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000235780	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L27	ubiquitin specific peptidase 17 like family member 27 [Source:HGNC Symbol;Acc:HGNC:44455]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0003723//RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0005540//hyaluronic acid binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1904037//positive regulation of epithelial cell apoptotic process	--
ENSG00000235863	1.84	2.056	3.143	2.79	2.346	2.14	65	73	82	73	70	55	B3GALT4	"beta-1,3-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:919]"	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K00715;K00715	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0031984//organelle subcompartment	"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity;GO:0019901//protein kinase binding;GO:0047915//ganglioside galactosyltransferase activity"	GO:0001574//ganglioside biosynthetic process;GO:0006486//protein glycosylation;GO:0006629//lipid metabolic process;GO:0009312//oligosaccharide biosynthetic process	--
ENSG00000235942	0	0	0	0	0	0	0	0	0	0	0	0	LCE6A	late cornified envelope 6A [Source:HGNC Symbol;Acc:HGNC:31824]	-	-	-	-	-	-	GO:0031424//keratinization	--
ENSG00000235961	6.484	6.987	7.438	9.423	8.108	9.267	301	326	255	324	318	313	PNMA6A	PNMA family member 6A [Source:HGNC Symbol;Acc:HGNC:28248]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000236027	0	0	0	0	0	0	0	0	0	0	0	0	PATE3	prostate and testis expressed 3 [Source:HGNC Symbol;Acc:HGNC:35426]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25370	GO:0005576//extracellular region	-	-	--
ENSG00000236032	0	0	0	0	0	0	0	0	0	0	0	0	OR5H14	olfactory receptor family 5 subfamily H member 14 [Source:HGNC Symbol;Acc:HGNC:31286]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000236104	5.093	6.113	7.571	6.313	5.814	7.594	281	339	308	258	271	293	ZBTB22	zinc finger and BTB domain containing 22 [Source:HGNC Symbol;Acc:HGNC:13085]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000236125	0	0	0	0	0	0	0	0	0	0	0	0	USP17L4	ubiquitin specific peptidase 17 like family member 4 [Source:HGNC Symbol;Acc:HGNC:37176]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase	GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000236126	0	0	0	0	0	0	0	0	0	0	0	0	CT47A3	cancer/testis antigen family 47 member A3 [Source:HGNC Symbol;Acc:HGNC:33284]	-	-	-	-	-	-	-	--
ENSG00000236170	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1-1	immunoglobulin heavy diversity 1-1 [Source:HGNC Symbol;Acc:HGNC:5482]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000236279	0.031	0.031	0.043	0.213	0.335	0.043	1	1	1	5	9	1	CLEC2L	C-type lectin domain family 2 member L [Source:HGNC Symbol;Acc:HGNC:21969]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding	-	--
ENSG00000236287	17.518	13.553	14.822	12.17	13.55	15.714	962	750	610	498	635	630	ZBED5	zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803]	-	-	-	-	-	GO:0003677//DNA binding;GO:0046872//metal ion binding	-	zf-BED
ENSG00000236320	0	0	0	0	0	0	0	0	0	0	0	0	SLFN14	schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004521//endoribonuclease activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0043022//ribosome binding	"GO:0006402//mRNA catabolic process;GO:0016075//rRNA catabolic process;GO:0036345//platelet maturation;GO:0071286//cellular response to magnesium ion;GO:0071287//cellular response to manganese ion;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000236334	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4G	peptidylprolyl isomerase A like 4G [Source:HGNC Symbol;Acc:HGNC:33996]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000236362	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12F	G antigen 12F [Source:HGNC Symbol;Acc:HGNC:31906]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000236371	0	0	0	0	0	0	0	0	0	0	0	0	CT47A1	cancer/testis antigen family 47 member A1 [Source:HGNC Symbol;Acc:HGNC:33282]	-	-	-	-	-	-	-	--
ENSG00000236383	0	0	0	0	0	0	0	0	0	0	0	0	CCDC200	coiled-coil domain containing 200 [Source:HGNC Symbol;Acc:HGNC:43658]	-	-	-	-	-	-	-	--
ENSG00000236396	0	0	0	0	0	0	0	0	0	0	0	0	SLC35G4	solute carrier family 35 member G4 [Source:HGNC Symbol;Acc:HGNC:31043]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000236398	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R39	taste 2 receptor member 39 [Source:HGNC Symbol;Acc:HGNC:18886]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000236424	0	0	0	0	0	0	0	0	0	0	0	0	TSPY10	testis specific protein Y-linked 10 [Source:HGNC Symbol;Acc:HGNC:37473]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation	--
ENSG00000236444	0	0	0	0	0	0	0	0	0	0	0	0	UBE2L5	ubiquitin conjugating enzyme E2 L5 [Source:HGNC Symbol;Acc:HGNC:13477]	Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease;ko04120//Ubiquitin mediated proteolysis	K04552;K04552;K04552	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity	GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0070979//protein K11-linked ubiquitination	--
ENSG00000236446	0	0	0	0	0	0	0	0	0	0	0	0	CT47B1	cancer/testis antigen family 47 member B1 [Source:HGNC Symbol;Acc:HGNC:33293]	-	-	-	-	-	-	-	--
ENSG00000236543	0	0	0	0	0	0	0	0	0	0	0	0	--	novel beta-lactoglobulin-like protein	-	-	-	-	GO:0005576//extracellular region	GO:0036094//small molecule binding	-	--
ENSG00000236597	0	0	0	0	0	0	0	0	0	0	0	0	IGHD7-27	immunoglobulin heavy diversity 7-27 [Source:HGNC Symbol;Acc:HGNC:5518]	-	-	-	-	-	-	-	--
ENSG00000236609	11.055	11.11	11.623	8.624	8.802	10.392	886	895	688	512	596	606	ZNF853	zinc finger protein 853 [Source:HGNC Symbol;Acc:HGNC:21767]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000236637	0	0	0	0	0	0	0	0	0	0	0	0	IFNA4	interferon alpha 4 [Source:HGNC Symbol;Acc:HGNC:5425]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune disease;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko05320//Autoimmune thyroid disease;ko04620//Toll-like receptor signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414;K05414	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005132//type I interferon receptor binding;GO:0005515//protein binding	GO:0002250//adaptive immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006952//defense response;GO:0006959//humoral immune response;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000236699	0	0.035	0.024	0	0.01	0	0	4	2	0	1	0	ARHGEF38	Rho guanine nucleotide exchange factor 38 [Source:HGNC Symbol;Acc:HGNC:25968]	-	-	-	-	GO:0005737//cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0050790//regulation of catalytic activity	--
ENSG00000236737	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12B	G antigen 12B [Source:HGNC Symbol;Acc:HGNC:26779]	-	-	-	-	-	-	-	--
ENSG00000236761	0	0	0	0	0	0	0	0	0	0	0	0	CTAGE9	CTAGE family member 9 [Source:HGNC Symbol;Acc:HGNC:37275]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000236782	1.589	1.929	0.678	2.224	2.536	2.964	36.35	46.35	15.24	37.41	48.72	44.35	ZNF593OS	ZNF593 opposite strand [Source:HGNC Symbol;Acc:HGNC:41278]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000236980	0	0	0	0	0	0	0	0	0	0	0	0	C3orf84	chromosome 3 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:44666]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000236981	0	0	0	0	0	0	0	0	0	0	0	0	OR10G9	olfactory receptor family 10 subfamily G member 9 [Source:HGNC Symbol;Acc:HGNC:15129]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000237020	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1-20	immunoglobulin heavy diversity 1-20 [Source:HGNC Symbol;Acc:HGNC:5484]	-	-	-	-	-	-	-	--
ENSG00000237038	0	0	0	0	0	0	0	0	0	0	0	0	USP17L8	ubiquitin specific peptidase 17 like family member 8 [Source:HGNC Symbol;Acc:HGNC:37181]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000237110	0	0	0	0	0	0	0	0	0	0	0	0	TAAR9	trace amine associated receptor 9 [Source:HGNC Symbol;Acc:HGNC:20977]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05051	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001594//trace-amine receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000237136	0	0	0	0	0	0	0	0	0	0	0	0	C4orf51	chromosome 4 open reading frame 51 [Source:HGNC Symbol;Acc:HGNC:37264]	-	-	-	-	-	-	-	--
ENSG00000237172	18.837	19.351	19.956	16.174	18.807	16.841	1055.7	1090.08	826.04	671.43	890.52	686.74	B3GNT9	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:28714]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008194//UDP-glycosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0016758//hexosyltransferase activity	GO:0006486//protein glycosylation;GO:0030311//poly-N-acetyllactosamine biosynthetic process	--
ENSG00000237190	14.369	12.811	13.396	15.742	12.036	14.173	366	328	252	297	259	262	CDKN2AIPNL	CDKN2A interacting protein N-terminal like [Source:HGNC Symbol;Acc:HGNC:30545]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005730//nucleolus	GO:0005515//protein binding	-	--
ENSG00000237197	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1-7	immunoglobulin heavy diversity 1-7 [Source:HGNC Symbol;Acc:HGNC:5486]	-	-	-	-	-	-	-	--
ENSG00000237235	0	0	0	0	0	0	0	0	0	0	0	0	TRDD2	T cell receptor delta diversity 2 [Source:HGNC Symbol;Acc:HGNC:12255]	-	-	-	-	-	-	-	--
ENSG00000237247	0	0	0	0	0	0	0	0	0	0	0	0	MBD3L5	methyl-CpG binding domain protein 3 like 5 [Source:HGNC Symbol;Acc:HGNC:37204]	-	-	-	-	-	-	-	--
ENSG00000237289	0.481	0.115	0.115	0	0.417	0.314	15.19	3.45	1.11	0	7	2.81	CKMT1B	"creatine kinase, mitochondrial 1B [Source:HGNC Symbol;Acc:HGNC:1995]"	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K00933;K00933	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004111//creatine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0016310//phosphorylation;GO:0019752//carboxylic acid metabolic process;GO:0046314//phosphocreatine biosynthetic process	--
ENSG00000237330	0	0.05	0	0	0	0	0	2	0	0	0	0	RNF223	ring finger protein 223 [Source:HGNC Symbol;Acc:HGNC:40020]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000237353	0	0	0	0	0	0	0	0	0	0	0	0	PATE4	prostate and testis expressed 4 [Source:HGNC Symbol;Acc:HGNC:35427]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K25370	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle	GO:0030548//acetylcholine receptor regulator activity	GO:0099601//regulation of neurotransmitter receptor activity	--
ENSG00000237378	0	0	0	0	0	0	0	0	0	0	0	0	--	novel keratin-associated protein	-	-	-	-	-	-	GO:0001942//hair follicle development	--
ENSG00000237388	0	0	0	0	0	0	0	0	0	0	0	0	OR4A47	olfactory receptor family 4 subfamily A member 47 [Source:HGNC Symbol;Acc:HGNC:31266]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000237412	0	0	0	0	0	0	0	0	0	0	0	0	PRSS56	serine protease 56 [Source:HGNC Symbol;Acc:HGNC:39433]	-	-	-	-	GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0043010//camera-type eye development	--
ENSG00000237440	3.849	4.347	4.725	5.982	3.787	4.869	181	162	130	133	131.02	140	ZNF737	zinc finger protein 737 [Source:HGNC Symbol;Acc:HGNC:32468]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000237441	22.094	22.018	24.711	22.083	22.072	25.279	1284	1271	1063	975	1104	1074	RGL2	ral guanine nucleotide dissociation stimulator like 2 [Source:HGNC Symbol;Acc:HGNC:9769]	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17636	GO:0005575//cellular_component;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0032485//regulation of Ral protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity	--
ENSG00000237452	0	0	0	0	0	0	0	0	0	0	0	0	MEIOSIN	meiosis initiator [Source:HGNC Symbol;Acc:HGNC:44318]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0046983//protein dimerization activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0007283//spermatogenesis;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle;GO:0071300//cellular response to retinoic acid;GO:0090427//activation of meiosis	HMG
ENSG00000237489	0.761	0.677	0.442	1.187	0.826	0.708	16	15	12	19	16	11	C10orf143	chromosome 10 open reading frame 143 [Source:HGNC Symbol;Acc:HGNC:48677]	-	-	-	-	-	-	-	--
ENSG00000237515	0.519	0.464	0.408	0.593	0.406	0.427	71.21	61.69	36.71	56.03	44.61	41.46	SHISA9	shisa family member 9 [Source:HGNC Symbol;Acc:HGNC:37231]	-	-	-	-	GO:0005886//plasma membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0032281//AMPA glutamate receptor complex;GO:0032591//dendritic spine membrane;GO:0042995//cell projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0098978//glutamatergic synapse;GO:0099061//integral component of postsynaptic density membrane	GO:0030165//PDZ domain binding	GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0098962//regulation of postsynaptic neurotransmitter receptor activity;GO:2000311//regulation of AMPA receptor activity	--
ENSG00000237521	0	0	0	0	0	0	0	0	0	0	0	0	OR7E24	olfactory receptor family 7 subfamily E member 24 [Source:HGNC Symbol;Acc:HGNC:8396]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000237524	0	0	0	0	0	0	0	0	0	0	0	0	TEX51	testis expressed 51 [Source:HGNC Symbol;Acc:HGNC:52387]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000237541	0	0	0	0	0.039	0	0	0	0	0	1	0	HLA-DQA2	"major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0042613//MHC class II protein complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000237621	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000237649	0.746	0.481	0.792	0.98	0.835	0.388	37	24	29	36	35	14	KIFC1	kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATP hydrolysis activity	GO:0000070//mitotic sister chromatid segregation;GO:0007018//microtubule-based movement;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0051301//cell division;GO:0090307//mitotic spindle assembly	--
ENSG00000237651	2.417	3.06	1.611	2.526	1.405	2.016	43	49	18	30	21	26	C2orf74	chromosome 2 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:34439]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000237671	0	0	0	0	0	0	0	0	0	0	0	0	GAGE12C	G antigen 12C [Source:HGNC Symbol;Acc:HGNC:28402]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000237693	0	0	0	0	0	0	0	0	0	0	0	0	IRGM	immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597]	Human Diseases	Infectious disease: parasitic	ko05145//Toxoplasmosis	K14139	GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane;GO:0001891//phagocytic cup;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity;GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0050700//CARD domain binding;GO:0051434//BH3 domain binding	GO:0000045//autophagosome assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0006914//autophagy;GO:0006952//defense response;GO:0006954//inflammatory response;GO:0010508//positive regulation of autophagy;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0031648//protein destabilization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0035458//cellular response to interferon-beta;GO:0042742//defense response to bacterium;GO:0043254//regulation of protein-containing complex assembly;GO:0045087//innate immune response;GO:0050821//protein stabilization;GO:0050829//defense response to Gram-negative bacterium;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0061635//regulation of protein complex stability;GO:0061739//protein lipidation involved in autophagosome assembly;GO:0061762//CAMKK-AMPK signaling cascade;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0098586//cellular response to virus;GO:1901098//positive regulation of autophagosome maturation	--
ENSG00000237700	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF33	PRAME family member 33 [Source:HGNC Symbol;Acc:HGNC:49193]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000237763	0	0	0	0	0	0	0	0	0	0	0	0	AMY1A	amylase alpha 1A [Source:HGNC Symbol;Acc:HGNC:474]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism	K01176;K01176;K01176;K01176;K01176	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004556//alpha-amylase activity;GO:0005509//calcium ion binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0031404//chloride ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0103025//alpha-amylase activity (releasing maltohexaose)"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process;GO:0009311//oligosaccharide metabolic process	--
ENSG00000237765	9.156	8.883	9.113	8.095	6.245	10.278	366	339	255	247	218	287	FAM200B	family with sequence similarity 200 member B [Source:HGNC Symbol;Acc:HGNC:27740]	-	-	-	-	-	-	-	--
ENSG00000237850	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L24P	"golgin A6 family like 24, pseudogene [Source:HGNC Symbol;Acc:HGNC:55710]"	-	-	-	-	-	-	-	--
ENSG00000237957	0	0	0	0	0	0	0	0	0	0	0	0	CT47A5	cancer/testis antigen family 47 member A5 [Source:HGNC Symbol;Acc:HGNC:33286]	-	-	-	-	-	-	-	--
ENSG00000237988	0	0.041	0.072	0.044	0.039	0.03	0	4.26	5.47	3.37	3.37	2.21	OR2I1P	olfactory receptor family 2 subfamily I member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:8258]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000238074	0	0	0	0	0	0	0	0	0	0	0	0	TSPY9P	"testis specific protein Y-linked 9, pseudogene [Source:HGNC Symbol;Acc:HGNC:37472]"	-	-	-	-	GO:0005634//nucleus	-	GO:0006334//nucleosome assembly	--
ENSG00000238083	1.21	1.144	0.949	1.002	0.955	0.692	142.23	135.21	82.45	87.24	94.9	59.17	LRRC37A2	leucine rich repeat containing 37 member A2 [Source:HGNC Symbol;Acc:HGNC:32404]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000238205	0	0	0	0	0	0	0	0	0	0	0	0	MPC1L	mitochondrial pyruvate carrier 1 like [Source:HGNC Symbol;Acc:HGNC:44205]	Human Diseases	Cardiovascular disease	ko05415//Diabetic cardiomyopathy	K22138	GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0050833//pyruvate transmembrane transporter activity	GO:0006850//mitochondrial pyruvate transmembrane transport	--
ENSG00000238210	0	0	0	0	0	0	0	0	0	0	0	0	ETDA	embryonic testis differentiation homolog A [Source:HGNC Symbol;Acc:HGNC:53449]	-	-	-	-	-	-	-	--
ENSG00000238227	14.953	13.46	14.604	17.774	16.58	17.473	838	779	610	772	819	726	TMEM250	transmembrane protein 250 [Source:HGNC Symbol;Acc:HGNC:31009]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005940//septin ring;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031105//septin complex;GO:0032153//cell division site	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0060090//molecular adaptor activity	GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0034613//cellular protein localization;GO:0048524//positive regulation of viral process;GO:0060271//cilium assembly;GO:0061640//cytoskeleton-dependent cytokinesis	--
ENSG00000238243	0.51	0.102	0.138	0.344	0.242	0.21	10	2	2	5	4	3	OR2W3	olfactory receptor family 2 subfamily W member 3 [Source:HGNC Symbol;Acc:HGNC:15021]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000238269	0	0	0	0	0	0	0	0	0	0	0	0	PAGE2B	PAGE family member 2B [Source:HGNC Symbol;Acc:HGNC:31805]	-	-	-	-	-	-	-	--
ENSG00000239264	81.113	87.063	67.032	68.271	78.523	69.837	4943	5332.89	3017	3081.75	4036.58	3085	TXNDC5	thioredoxin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21073]	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K13984	GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0070062//extracellular exosome	GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding	GO:0043066//negative regulation of apoptotic process;GO:0043277//apoptotic cell clearance	--
ENSG00000239282	5.083	5.275	6.831	10.079	6.214	7.249	149.91	158.32	145.85	212.64	162.72	154.77	CASTOR1	cytosolic arginine sensor for mTORC1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:34423]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K23080	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0061700//GATOR2 complex	GO:0005515//protein binding;GO:0034618//arginine binding;GO:0042802//identical protein binding	GO:1902531//regulation of intracellular signal transduction;GO:1903432//regulation of TORC1 signaling;GO:1903577//cellular response to L-arginine;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000239305	25.836	24.313	25.458	21.664	21.743	25.043	1866	1765	1358	1159	1326.74	1316	RNF103	ring finger protein 103 [Source:HGNC Symbol;Acc:HGNC:12859]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044322//endoplasmic reticulum quality control compartment	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007417//central nervous system development;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:1904380//endoplasmic reticulum mannose trimming	--
ENSG00000239306	11.771	11.922	15.018	11.708	12.013	19.33	767.27	874.89	688.01	654.61	815.75	687.32	RBM14	RNA binding motif protein 14 [Source:HGNC Symbol;Acc:HGNC:14219]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0030374//nuclear receptor coactivator activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0009725//response to hormone;GO:0016575//histone deacetylation;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046600//negative regulation of centriole replication;GO:0060395//SMAD protein signal transduction;GO:0098534//centriole assembly"	--
ENSG00000239382	5.275	6.297	4.76	5.357	5.78	5.352	107	126	71	79	98	78	ALKBH6	alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005925//focal adhesion	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity	-	--
ENSG00000239388	0.166	0.135	0.123	0.082	0.09	0.062	11	9	6	4	5	3	ASB14	ankyrin repeat and SOCS box containing 14 [Source:HGNC Symbol;Acc:HGNC:19766]	-	-	-	-	GO:0005829//cytosol	GO:0005515//protein binding	GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction	--
ENSG00000239389	0.056	0	0.049	0.027	0	0	5.66	0	3.66	1	0	0	PCDHA13	protocadherin alpha 13 [Source:HGNC Symbol;Acc:HGNC:8667]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000239395	0	0	0	0	0	0	0	0	0	0	0	0	OR14A2	novel protein	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000239474	0.268	0.2	0.261	0.238	0.123	0.129	13.67	10.25	9.85	9	5.3	4.79	KLHL41	kelch like family member 41 [Source:HGNC Symbol;Acc:HGNC:16905]	-	-	-	-	GO:0001726//ruffle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum;GO:0031143//pseudopodium;GO:0031430//M band;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0042995//cell projection	GO:0005515//protein binding	GO:0006941//striated muscle contraction;GO:0016567//protein ubiquitination;GO:0030239//myofibril assembly;GO:0035914//skeletal muscle cell differentiation;GO:0045214//sarcomere organization;GO:0045661//regulation of myoblast differentiation;GO:0048741//skeletal muscle fiber development;GO:2000291//regulation of myoblast proliferation;GO:2001014//regulation of skeletal muscle cell differentiation	--
ENSG00000239571	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-30	immunoglobulin kappa variable 2D-30 [Source:HGNC Symbol;Acc:HGNC:5801]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000239590	0	0	0	0	0	0	0	0	0	0	0	0	OR1J4	olfactory receptor family 1 subfamily J member 4 [Source:HGNC Symbol;Acc:HGNC:8211]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000239605	0	0	0	0	0	0	0	0	0	0	0	0	STPG4	sperm-tail PG-rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:26850]	-	-	-	-	GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0042585//germinal vesicle	GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006325//chromatin organization;GO:0044727//DNA demethylation of male pronucleus;GO:0090116//C-5 methylation of cytosine;GO:1901537//positive regulation of DNA demethylation	--
ENSG00000239620	0	0	0	0	0	0	0	0	0	0	0	0	PRR20G	proline rich 20G [Source:HGNC Symbol;Acc:HGNC:53837]	-	-	-	-	-	-	-	--
ENSG00000239642	0	0	0	0	0	0	0	0	0	0	0	0	MEIKIN	meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0005694//chromosome"	-	"GO:0007059//chromosome segregation;GO:0007060//male meiosis chromosome segregation;GO:0010789//meiotic sister chromatid cohesion involved in meiosis I;GO:0016321//female meiosis chromosome segregation;GO:0045143//homologous chromosome segregation;GO:0051321//meiotic cell cycle;GO:0051754//meiotic sister chromatid cohesion, centromeric"	--
ENSG00000239672	53.164	49.566	48.226	52.311	44.385	48.386	987.22	921.74	662.62	716.75	698.8	645.15	NME1	NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004536//deoxyribonuclease activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0042802//identical protein binding;GO:0043024//ribosomal small subunit binding;GO:0046872//metal ion binding	GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006259//DNA metabolic process;GO:0006897//endocytosis;GO:0007399//nervous system development;GO:0007595//lactation;GO:0008285//negative regulation of cell population proliferation;GO:0009117//nucleotide metabolic process;GO:0016310//phosphorylation;GO:0030154//cell differentiation;GO:0030879//mammary gland development;GO:0042981//regulation of apoptotic process;GO:0043388//positive regulation of DNA binding;GO:0050679//positive regulation of epithelial cell proliferation;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000239697	5.726	6.995	5.73	7.298	8.061	6.5	164	202	122	156	197	136	TNFSF12	TNF superfamily member 12 [Source:HGNC Symbol;Acc:HGNC:11927]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05474	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0048018//receptor ligand activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation;GO:0043542//endothelial cell migration;GO:0045732//positive regulation of protein catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0097191//extrinsic apoptotic signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway	--
ENSG00000239704	0	0.228	0	0.515	0.361	0	0	3	0	5	4	0	CDRT4	CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000239713	0	0.031	0	0	0	0	0	1	0	0	0	0	APOBEC3G	apolipoprotein B mRNA editing enzyme catalytic subunit 3G [Source:HGNC Symbol;Acc:HGNC:17357]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008829//dCTP deaminase activity;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002230//positive regulation of defense response to virus by host;GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016553//base conversion or substitution editing;GO:0016554//cytidine to uridine editing;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0048525//negative regulation of viral process;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000239732	0.187	0.057	0.136	0.019	0.187	0.119	13	4	7	1	11	6	TLR9	toll like receptor 9 [Source:HGNC Symbol;Acc:HGNC:15633]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Cancer: overview;Infectious disease: parasitic	ko05168//Herpes simplex virus 1 infection;ko05132//Salmonella infection;ko05152//Tuberculosis;ko05162//Measles;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05143//African trypanosomiasis;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05144//Malaria	K10161;K10161;K10161;K10161;K10161;K10161;K10161;K10161;K10161	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0032009//early phagosome;GO:0036019//endolysosome;GO:0036020//endolysosome membrane;GO:0045335//phagocytic vesicle	GO:0003953//NAD+ nucleosidase activity;GO:0004888//transmembrane signaling receptor activity;GO:0005149//interleukin-1 receptor binding;GO:0005515//protein binding;GO:0035197//siRNA binding;GO:0038187//pattern recognition receptor activity;GO:0042803//protein homodimerization activity;GO:0045322//unmethylated CpG binding	GO:0001817//regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0002639//positive regulation of immunoglobulin production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007252//I-kappaB phosphorylation;GO:0010628//positive regulation of gene expression;GO:0030277//maintenance of gastrointestinal epithelium;GO:0030890//positive regulation of B cell proliferation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0032717//negative regulation of interleukin-8 production;GO:0032722//positive regulation of chemokine production;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0032729//positive regulation of interferon-gamma production;GO:0032733//positive regulation of interleukin-10 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032741//positive regulation of interleukin-18 production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034163//regulation of toll-like receptor 9 signaling pathway;GO:0042742//defense response to bacterium;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043410//positive regulation of MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0045087//innate immune response;GO:0045577//regulation of B cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0046330//positive regulation of JNK cascade;GO:0050729//positive regulation of inflammatory response;GO:0050829//defense response to Gram-negative bacterium;GO:0050871//positive regulation of B cell activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1901895//negative regulation of ATPase-coupled calcium transmembrane transporter activity	--
ENSG00000239779	45.148	50.825	54.879	57.582	54.4	46.373	1107.32	1251.65	992.98	1047	1125	829.57	WBP1	WW domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12737]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0050699//WW domain binding	GO:0008150//biological_process	--
ENSG00000239789	2.561	1.977	2.679	2.569	1.657	2.512	94.88	73.61	73.29	70.5	51.87	67.7	MRPS17	mitochondrial ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:14047]	Genetic Information Processing	Translation	ko03010//Ribosome	K02961	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000239810	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF11	PRAME family member 11 [Source:HGNC Symbol;Acc:HGNC:14086]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000239819	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-8	immunoglobulin kappa variable 1D-8 [Source:HGNC Symbol;Acc:HGNC:5759]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000239839	0	0	0	0	0	0	0	0	0	0	0	0	DEFA3	defensin alpha 3 [Source:HGNC Symbol;Acc:HGNC:2762]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0035578//azurophil granule lumen;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0042803//protein homodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006952//defense response;GO:0019730//antimicrobial humoral response;GO:0019731//antibacterial humoral response;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051607//defense response to virus;GO:0051673//membrane disruption in other organism;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000239855	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-6	immunoglobulin kappa variable 1-6 [Source:HGNC Symbol;Acc:HGNC:5742]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000239857	8.726	8.081	10.636	9.608	9.567	9.506	392	358.5	347	321	366	310	GET4	guided entry of tail-anchored proteins factor 4 [Source:HGNC Symbol;Acc:HGNC:21690]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071818//BAT3 complex	GO:0005515//protein binding;GO:0051087//chaperone binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0031647//regulation of protein stability;GO:0045048//protein insertion into ER membrane;GO:0051220//cytoplasmic sequestering of protein;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1904378//maintenance of unfolded protein involved in ERAD pathway	--
ENSG00000239862	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-37	immunoglobulin kappa variable 1-37 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5739]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000239886	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-2	keratin associated protein 9-2 [Source:HGNC Symbol;Acc:HGNC:16926]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000239887	7.009	7.159	7.861	8.044	8.008	8.52	599.29	591.41	496.36	509.41	578.46	530.04	C1orf226	chromosome 1 open reading frame 226 [Source:HGNC Symbol;Acc:HGNC:34351]	Organismal Systems	Environmental adaptation	ko04713//Circadian entrainment	K16513	-	-	-	--
ENSG00000239900	36.746	38.207	35.46	35.111	34.267	35.065	1197.68	1255.29	906.66	894.74	937.87	851.23	ADSL	adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291]	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K01756;K01756;K01756	GO:0005829//cytosol;GO:0032991//protein-containing complex	"GO:0003824//catalytic activity;GO:0004018//N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity;GO:0016829//lyase activity;GO:0042802//identical protein binding;GO:0070626//(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity"	GO:0001666//response to hypoxia;GO:0006163//purine nucleotide metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0007584//response to nutrient;GO:0009060//aerobic respiration;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0014850//response to muscle activity;GO:0042594//response to starvation;GO:0044208//'de novo' AMP biosynthetic process;GO:0044209//AMP salvage;GO:0097294//'de novo' XMP biosynthetic process	--
ENSG00000239920	0	0	0	0	0	0	0	0	0	0	0	0	TRIM5	novel transcript	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K10648	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046596//regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity	--
ENSG00000239951	0	0	0	0	2.283	0	0	0	0	0	16	0	IGKV3-20	immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071751//secretory IgA immunoglobulin complex;GO:0071756//pentameric IgM immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0003094//glomerular filtration;GO:0006955//immune response;GO:0019731//antibacterial humoral response	--
ENSG00000239961	0	0	0	0	0.058	0	0	0	0	0	2	0	LILRA4	leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032998//Fc-epsilon receptor I complex	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0032396//inhibitory MHC class I receptor activity	GO:0002376//immune system process;GO:0019221//cytokine-mediated signaling pathway;GO:0032687//negative regulation of interferon-alpha production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034156//negative regulation of toll-like receptor 7 signaling pathway;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045087//innate immune response	--
ENSG00000239975	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-33	immunoglobulin kappa variable 1D-33 [Source:HGNC Symbol;Acc:HGNC:5753]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000239998	0	0	0	0	0	0	0	0	0	0	0	0	LILRA2	leukocyte immunoglobulin like receptor A2 [Source:HGNC Symbol;Acc:HGNC:6603]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0001791//IgM binding;GO:0003823//antigen binding;GO:0032396//inhibitory MHC class I receptor activity;GO:0038023//signaling receptor activity	GO:0002220//innate immune response activating cell surface receptor signaling pathway;GO:0002283//neutrophil activation involved in immune response;GO:0002376//immune system process;GO:0006952//defense response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032755//positive regulation of interleukin-6 production;GO:0032757//positive regulation of interleukin-8 production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0045087//innate immune response;GO:0050867//positive regulation of cell activation;GO:0051928//positive regulation of calcium ion transport;GO:0071657//positive regulation of granulocyte colony-stimulating factor production	--
ENSG00000240021	0	0	0	0	0	0	0	0	0	0	0	0	TEX35	testis expressed 35 [Source:HGNC Symbol;Acc:HGNC:25366]	-	-	-	-	GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton	GO:0005515//protein binding	-	--
ENSG00000240038	0.2	0.219	0.338	0.646	0.417	1.022	8.1	9.55	9	19.48	18.55	24	AMY2B	amylase alpha 2B [Source:HGNC Symbol;Acc:HGNC:478]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism	K01176;K01176;K01176;K01176;K01176	GO:0005576//extracellular region;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004556//alpha-amylase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0103025//alpha-amylase activity (releasing maltohexaose)"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000240041	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ4	immunoglobulin heavy joining 4 [Source:HGNC Symbol;Acc:HGNC:5538]	-	-	-	-	-	-	-	--
ENSG00000240045	0	0	0	0	0	0	0	0	0	0	0	0	STRIT1	small transmembrane regulator of ion transport 1 [Source:HGNC Symbol;Acc:HGNC:52297]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane	GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0031449//regulation of slow-twitch skeletal muscle fiber contraction;GO:0050790//regulation of catalytic activity;GO:1901894//regulation of ATPase-coupled calcium transmembrane transporter activity;GO:1902082//positive regulation of calcium ion import into sarcoplasmic reticulum	--
ENSG00000240053	0.628	0.902	1.099	0.729	1.556	1.474	25.1	31.78	30.38	26.62	43.02	45.45	LY6G5B	lymphocyte antigen 6 family member G5B [Source:HGNC Symbol;Acc:HGNC:13931]	-	-	-	-	GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0032991//protein-containing complex	GO:0042802//identical protein binding	-	--
ENSG00000240065	0.332	0.687	1.235	0.68	1.318	0.977	7	7	9	6	17	15	PSMB9	proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546]	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K02741	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome;GO:1990111//spermatoproteasome complex"	GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006508//proteolysis;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:2000116//regulation of cysteine-type endopeptidase activity"	--
ENSG00000240184	27.596	27.562	31.063	34.355	29.312	30.83	2346.72	2419.88	1980.74	2054.08	2261.84	2078.34	PCDHGC3	"protocadherin gamma subfamily C, 3 [Source:HGNC Symbol;Acc:HGNC:8716]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0043524//negative regulation of neuron apoptotic process;GO:0050808//synapse organization	--
ENSG00000240204	0.1	0.495	0.404	0.403	0.412	0.41	2	10	6	6	7	6	SMKR1	small lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:43561]	-	-	-	-	-	-	-	--
ENSG00000240230	2.06	1.952	1.875	1.658	1.592	1.451	200.95	194.75	139	114.08	135	106	COX19	cytochrome c oxidase assembly factor COX19 [Source:HGNC Symbol;Acc:HGNC:28074]	Organismal Systems	Environmental adaptation	ko04714//Thermogenesis	K18183	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol	GO:0005515//protein binding	GO:0006878//cellular copper ion homeostasis;GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000240247	0	0	0	0	0	0	0	0	0	0	0	0	DEFA1B	defensin alpha 1B [Source:HGNC Symbol;Acc:HGNC:33596]	Human Diseases;Organismal Systems;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial	ko05202//Transcriptional misregulation in cancer;ko04621//NOD-like receptor signaling pathway;ko05150//Staphylococcus aureus infection	K05230;K05230;K05230	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0035578//azurophil granule lumen;GO:0062023//collagen-containing extracellular matrix;GO:0070062//extracellular exosome	GO:0005515//protein binding	GO:0002227//innate immune response in mucosa;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response;GO:0010818//T cell chemotaxis;GO:0019731//antibacterial humoral response;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031640//killing of cells of other organism;GO:0042742//defense response to bacterium;GO:0042832//defense response to protozoan;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0050832//defense response to fungus;GO:0051607//defense response to virus;GO:0051673//membrane disruption in other organism;GO:0051873//killing by host of symbiont cells;GO:0052337//modification by host of symbiont membrane;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000240303	4.89	4.245	3.742	4.134	3.94	4.041	302.36	278.54	168.68	181.11	220.59	185.18	ACAD11	acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211]	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0016020//membrane;GO:0031966//mitochondrial membrane	"GO:0003995//acyl-CoA dehydrogenase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase	--
ENSG00000240344	11.918	12.399	13.085	13.881	10.422	12.474	254	220	200	205	188	196	PPIL3	peptidylprolyl isomerase like 3 [Source:HGNC Symbol;Acc:HGNC:9262]	-	-	-	-	GO:0005681//spliceosomal complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0071013//catalytic step 2 spliceosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016853//isomerase activity	"GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006397//mRNA processing;GO:0006457//protein folding;GO:0008380//RNA splicing"	--
ENSG00000240382	0	0	0	0	0.604	0	0	0	0	0	4	0	IGKV1-17	immunoglobulin kappa variable 1-17 [Source:HGNC Symbol;Acc:HGNC:5733]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000240386	0	0	0	0	0	0	0	0	0	0	0	0	LCE1F	late cornified envelope 1F [Source:HGNC Symbol;Acc:HGNC:29467]	-	-	-	-	-	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000240403	0	0	0	0	0	0	0	0	0	0	0	0	KIR3DL2	"killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 [Source:HGNC Symbol;Acc:HGNC:6339]"	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K07980;K07980;K07980	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0023029//MHC class Ib protein binding	GO:0006968//cellular defense response;GO:1901215//negative regulation of neuron death	--
ENSG00000240432	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP13-3	keratin associated protein 13-3 [Source:HGNC Symbol;Acc:HGNC:18925]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000240445	4.922	3.004	4.872	2.024	3.163	2.859	407.84	336.22	259.59	182.24	264.62	193.92	FOXO3B	forkhead box O3B [Source:HGNC Symbol;Acc:HGNC:3822]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems	Signal transduction;Infectious disease: bacterial;Cancer: overview;Immune system;Cell growth and death;Endocrine and metabolic disease;Signal transduction;Nervous system;Signal transduction;Aging;Drug resistance: antineoplastic;Endocrine system;Transport and catabolism;Cancer: specific types;Aging;Cancer: specific types;Development and regeneration;Aging	ko04151//PI3K-Akt signaling pathway;ko05131//Shigellosis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko04062//Chemokine signaling pathway;ko04218//Cellular senescence;ko04936//Alcoholic liver disease;ko04068//FoxO signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04211//Longevity regulating pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko04917//Prolactin signaling pathway;ko04137//Mitophagy - animal;ko05223//Non-small cell lung cancer;ko04213//Longevity regulating pathway - multiple species;ko05213//Endometrial cancer;ko04361//Axon regeneration;ko04212//Longevity regulating pathway - worm	K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408;K09408	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000240505	0	0	0	0	0	0	0	0	0	0	0	0	TNFRSF13B	TNF receptor superfamily member 13B [Source:HGNC Symbol;Acc:HGNC:18153]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Immune disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production	K05150;K05150;K05150	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0001782//B cell homeostasis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0030889//negative regulation of B cell proliferation	--
ENSG00000240542	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-1	keratin associated protein 9-1 [Source:HGNC Symbol;Acc:HGNC:18912]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0031424//keratinization	--
ENSG00000240563	0.076	0	0.085	0.068	0.104	0	6	0	5	4	7	0	L1TD1	LINE1 type transposase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25595]	-	-	-	-	GO:0043231//intracellular membrane-bounded organelle;GO:1990904//ribonucleoprotein complex	GO:0003727//single-stranded RNA binding;GO:0005515//protein binding	"GO:0032197//transposition, RNA-mediated"	--
ENSG00000240583	103.634	101.628	121.865	103.561	117.732	116.521	5910	5829	5131	4382	5678	4843	AQP1	aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633]	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Endocrine system;Excretory system	ko04976//Bile secretion;ko04924//Renin secretion;ko04964//Proximal tubule bicarbonate reclamation	K09864;K09864;K09864	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031965//nuclear membrane;GO:0042383//sarcolemma;GO:0045177//apical part of cell;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0005223//intracellular cGMP-activated cation channel activity;GO:0005267//potassium channel activity;GO:0005372//water transmembrane transporter activity;GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity;GO:0015079//potassium ion transmembrane transporter activity;GO:0015168//glycerol transmembrane transporter activity;GO:0015250//water channel activity;GO:0015267//channel activity;GO:0022857//transmembrane transporter activity;GO:0030184//nitric oxide transmembrane transporter activity;GO:0035379//carbon dioxide transmembrane transporter activity;GO:0042802//identical protein binding	GO:0003091//renal water homeostasis;GO:0003097//renal water transport;GO:0006813//potassium ion transport;GO:0006833//water transport;GO:0006884//cell volume homeostasis;GO:0006972//hyperosmotic response;GO:0009992//cellular water homeostasis;GO:0015670//carbon dioxide transport;GO:0015793//glycerol transport;GO:0019725//cellular homeostasis;GO:0019934//cGMP-mediated signaling;GO:0021670//lateral ventricle development;GO:0030157//pancreatic juice secretion;GO:0030185//nitric oxide transport;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0033326//cerebrospinal fluid secretion;GO:0034644//cellular response to UV;GO:0035377//transepithelial water transport;GO:0035378//carbon dioxide transmembrane transport;GO:0042476//odontogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0046878//positive regulation of saliva secretion;GO:0048146//positive regulation of fibroblast proliferation;GO:0050829//defense response to Gram-negative bacterium;GO:0050891//multicellular organismal water homeostasis;GO:0055085//transmembrane transport;GO:0070301//cellular response to hydrogen peroxide;GO:0071241//cellular response to inorganic substance;GO:0071260//cellular response to mechanical stimulus;GO:0071280//cellular response to copper ion;GO:0071288//cellular response to mercury ion;GO:0071300//cellular response to retinoic acid;GO:0071320//cellular response to cAMP;GO:0071456//cellular response to hypoxia;GO:0071472//cellular response to salt stress;GO:0071474//cellular hyperosmotic response;GO:0071549//cellular response to dexamethasone stimulus;GO:0071732//cellular response to nitric oxide;GO:0071805//potassium ion transmembrane transport;GO:0072488//ammonium transmembrane transport	--
ENSG00000240654	0	0	0	0.107	0	0	0	0	0	3	0	0	C1QTNF9	C1q and TNF related 9 [Source:HGNC Symbol;Acc:HGNC:28732]	-	-	-	-	GO:0005576//extracellular region;GO:0005581//collagen trimer	GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007165//signal transduction	--
ENSG00000240671	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-8	immunoglobulin kappa variable 1-8 [Source:HGNC Symbol;Acc:HGNC:5743]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000240682	7.987	8.073	7.746	6.337	8.148	8.34	318.75	288.71	213.48	209.17	259.73	275.73	ISY1	ISY1 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:29201]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12870	GO:0000974//Prp19 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071014//post-mRNA release spliceosomal complex;GO:0071020//post-spliceosomal complex	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000240694	3.91	4.431	3.85	4.637	4.85	4.439	383.57	436.91	279	337	402	316.88	PNMA2	PNMA family member 2 [Source:HGNC Symbol;Acc:HGNC:9159]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0005515//protein binding	GO:0043065//positive regulation of apoptotic process	--
ENSG00000240720	0	0	0	0	0.02	0	0	0	0	0	1	0	LRRD1	leucine rich repeats and death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34300]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction;GO:0046579//positive regulation of Ras protein signal transduction	--
ENSG00000240747	0	0	0	0	0	0	0	0	0	0	0	0	KRBOX1	KRAB box domain containing 1 [Source:HGNC Symbol;Acc:HGNC:38708]	-	-	-	-	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000240764	0.209	0.053	0.071	0.048	0.062	0.147	12	5.3	3	3.53	3	10.62	PCDHGC5	"protocadherin gamma subfamily C, 5 [Source:HGNC Symbol;Acc:HGNC:8718]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0043524//negative regulation of neuron apoptotic process;GO:0050808//synapse organization	--
ENSG00000240771	4.873	5.597	5.71	4.513	5.439	4.618	244	294	213.63	168	234.57	178	ARHGEF25	Rho guanine nucleotide exchange factor 25 [Source:HGNC Symbol;Acc:HGNC:30275]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0030016//myofibril;GO:0030017//sarcomere	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007411//axon guidance;GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000240849	9.727	8.521	8.866	9.337	8.544	7.99	502.97	476.44	336.73	355.39	368	344	PEDS1	plasmanylethanolamine desaturase 1 [Source:HGNC Symbol;Acc:HGNC:16735]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00565//Ether lipid metabolism	K20656;K20656	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0050207//plasmanylethanolamine desaturase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0008611//ether lipid biosynthetic process	--
ENSG00000240857	13.104	10.3	12.846	13.685	11.632	13.762	424	335	307	328	318	324	RDH14	retinol dehydrogenase 14 [Source:HGNC Symbol;Acc:HGNC:19979]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005765//lysosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016020//membrane	GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0016491//oxidoreductase activity;GO:0052650//NADP-retinol dehydrogenase activity;GO:0102354//11-cis-retinol dehydrogenase activity	GO:0001649//osteoblast differentiation;GO:0006629//lipid metabolic process;GO:0042572//retinol metabolic process	--
ENSG00000240864	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-16	immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000240871	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-7	keratin associated protein 4-7 [Source:HGNC Symbol;Acc:HGNC:18898]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	GO:0007568//aging;GO:0042633//hair cycle	--
ENSG00000240891	1	0.827	0.593	0.54	0.511	0.662	160	133	70	64	69	77	PLCXD2	phosphatidylinositol specific phospholipase C X domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26462]	-	-	-	-	GO:0005634//nucleus	GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity	GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0016042//lipid catabolic process	--
ENSG00000240972	474.843	491.152	480.834	535.53	491.84	476.195	5486	5703.59	4102.88	4583	4800.77	4003	MIF	macrophage migration inhibitory factor [Source:HGNC Symbol;Acc:HGNC:7097]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko00350//Tyrosine metabolism;ko00360//Phenylalanine metabolism	K07253;K07253;K07253	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0031982//vesicle;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:1904813//ficolin-1-rich granule lumen	GO:0002020//protease binding;GO:0004167//dopachrome isomerase activity;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding;GO:0005515//protein binding;GO:0016853//isomerase activity;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0050178//phenylpyruvate tautomerase activity	"GO:0001516//prostaglandin biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0001934//positive regulation of protein phosphorylation;GO:0002376//immune system process;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0007569//cell aging;GO:0008284//positive regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0010739//positive regulation of protein kinase A signaling;GO:0010760//negative regulation of macrophage chemotaxis;GO:0019752//carboxylic acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030336//negative regulation of cell migration;GO:0030890//positive regulation of B cell proliferation;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032269//negative regulation of cellular protein metabolic process;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0042127//regulation of cell population proliferation;GO:0042327//positive regulation of phosphorylation;GO:0043030//regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045087//innate immune response;GO:0048146//positive regulation of fibroblast proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050918//positive chemotaxis;GO:0061078//positive regulation of prostaglandin secretion involved in immune response;GO:0061081//positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0070207//protein homotrimerization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090238//positive regulation of arachidonic acid secretion;GO:0090344//negative regulation of cell aging;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production"	--
ENSG00000241058	2.003	1.927	1.792	1.352	1.956	1.97	90	87	51	45	68	55	NSUN6	NOP2/Sun RNA methyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:23529]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0016740//transferase activity	GO:0001510//RNA methylation;GO:0002946//tRNA C5-cytosine methylation;GO:0006400//tRNA modification;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000241106	0.036	0	0	0	0	0	1	0	0	0	0	0	HLA-DOB	"major histocompatibility complex, class II, DO beta [Source:HGNC Symbol;Acc:HGNC:4937]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042613//MHC class II protein complex	GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000241119	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A9	UDP glucuronosyltransferase family 1 member A9 [Source:HGNC Symbol;Acc:HGNC:12541]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001972//retinoic acid binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0042573//retinoic acid metabolic process;GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation	--
ENSG00000241123	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-5	keratin associated protein 10-5 [Source:HGNC Symbol;Acc:HGNC:22969]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000241127	7.251	6.873	6.071	6.414	5.925	7.912	131	125	81	83	82	104	YAE1	YAE1 maturation factor of ABCE1 [Source:HGNC Symbol;Acc:HGNC:24857]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0106035//protein maturation by [4Fe-4S] cluster transfer	--
ENSG00000241128	0	0	0	0	0	0	0	0	0	0	0	0	OR14A2	olfactory receptor family 14 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:15024]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000241149	0	0	0	0	0	0	0	0	0	0	0	0	ZNF722P	"zinc finger protein 722, pseudogene [Source:HGNC Symbol;Acc:HGNC:22571]"	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000241186	0	0	0	0	0	0	0	0	0	0	0	0	TDGF1	teratocarcinoma-derived growth factor 1 [Source:HGNC Symbol;Acc:HGNC:11701]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0019897//extrinsic component of plasma membrane;GO:0031225//anchored component of membrane;GO:0045121//membrane raft	GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0038100//nodal binding;GO:0070697//activin receptor binding	"GO:0001568//blood vessel development;GO:0001763//morphogenesis of a branching structure;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0007165//signal transduction;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0008284//positive regulation of cell population proliferation;GO:0008595//anterior/posterior axis specification, embryo;GO:0009792//embryo development ending in birth or egg hatching;GO:0009952//anterior/posterior pattern specification;GO:0009966//regulation of signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0018105//peptidyl-serine phosphorylation;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0030879//mammary gland development;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0038092//nodal signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0048856//anatomical structure development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071346//cellular response to interferon-gamma;GO:0071354//cellular response to interleukin-6;GO:0071356//cellular response to tumor necrosis factor;GO:0071364//cellular response to epidermal growth factor stimulus"	--
ENSG00000241224	0	0.027	0	0	0	0.307	0	1	0	0	0	2	C3orf85	chromosome 3 open reading frame 85 [Source:HGNC Symbol;Acc:HGNC:53432]	-	-	-	-	-	-	-	--
ENSG00000241233	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-8	keratin associated protein 5-8 [Source:HGNC Symbol;Acc:HGNC:23603]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0030280//structural constituent of skin epidermis	GO:0008150//biological_process	--
ENSG00000241241	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-16	keratin associated protein 4-16 [Source:HGNC Symbol;Acc:HGNC:18921]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0031424//keratinization	--
ENSG00000241244	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-16	immunoglobulin kappa variable 1D-16 [Source:HGNC Symbol;Acc:HGNC:5748]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000241258	10.783	10.51	8.925	10.773	10.201	12.747	505.7	469	341.71	360	345.94	367.93	CRCP	CGRP receptor component [Source:HGNC Symbol;Acc:HGNC:17888]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K25304	GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//RNA polymerase III complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009360//DNA polymerase III complex;GO:0016020//membrane;GO:0030880//RNA polymerase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0001635//calcitonin gene-related peptide receptor activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006352//DNA-templated transcription, initiation;GO:0006383//transcription by RNA polymerase III;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0007218//neuropeptide signaling pathway;GO:0044237//cellular metabolic process;GO:0045087//innate immune response;GO:0051607//defense response to virus"	--
ENSG00000241294	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2-24	immunoglobulin kappa variable 2-24 [Source:HGNC Symbol;Acc:HGNC:5781]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000241322	0.1	0.069	0	0	0.037	0.026	4.76	2	0	0	1	3	CDRT1	CMT1A duplicated region transcript 1 [Source:HGNC Symbol;Acc:HGNC:14379]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000241343	220.271	219.635	221.877	220.057	167.366	175.437	2278.49	2236.33	1745.49	1649.73	1511.74	1347.14	RPL36A	ribosomal protein L36a [Source:HGNC Symbol;Acc:HGNC:10359]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02929;K02929	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0042788//polysomal ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000241351	0	0	0	0	4.513	0	0	0	0	0	31	0	IGKV3-11	immunoglobulin kappa variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5815]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000241356	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000241360	15.376	15.454	17.351	19.642	14.509	18.469	607.55	613.53	490.35	561.89	499.08	559	PDXP	pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00750//Vitamin B6 metabolism	K07758;K07758	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030496//midbody;GO:0031258//lamellipodium membrane;GO:0032154//cleavage furrow;GO:0032587//ruffle membrane;GO:0042995//cell projection;GO:0070938//contractile ring	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0031072//heat shock protein binding;GO:0033883//pyridoxal phosphatase activity;GO:0042803//protein homodimerization activity;GO:0043136//glycerol-3-phosphatase activity;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0007088//regulation of mitotic nuclear division;GO:0016311//dephosphorylation;GO:0030836//positive regulation of actin filament depolymerization;GO:0031247//actin rod assembly;GO:0032361//pyridoxal phosphate catabolic process;GO:0032465//regulation of cytokinesis;GO:0071318//cellular response to ATP	--
ENSG00000241370	9.205	12.401	12.145	15.321	13.828	17.44	103	138	99	126	130	140	RPP21	ribonuclease P/MRP subunit p21 [Source:HGNC Symbol;Acc:HGNC:21300]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex;GO:1902494//catalytic complex;GO:1990904//ribonucleoprotein complex	GO:0003723//RNA binding;GO:0004526//ribonuclease P activity;GO:0016787//hydrolase activity;GO:0033204//ribonuclease P RNA binding;GO:0046872//metal ion binding	"GO:0001682//tRNA 5'-leader removal;GO:0006396//RNA processing;GO:0008033//tRNA processing;GO:0009410//response to xenobiotic stimulus;GO:0034470//ncRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000241399	20.459	15.911	21.719	26.046	27.795	32.161	1661.62	1298.74	1303.72	1570.75	1906.7	1904.48	CD302	CD302 molecule [Source:HGNC Symbol;Acc:HGNC:30843]	-	-	-	-	GO:0005737//cytoplasm;GO:0005902//microvillus;GO:0005938//cell cortex;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030175//filopodium;GO:0042995//cell projection	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity	GO:0006909//phagocytosis	--
ENSG00000241404	0.758	0.37	1.098	1.277	0.323	0.943	19.21	9.39	21.84	23.64	6.47	17.31	EGFL8	EGF like domain multiple 8 [Source:HGNC Symbol;Acc:HGNC:13944]	-	-	-	-	GO:0005576//extracellular region;GO:0009986//cell surface	GO:0005102//signaling receptor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0048856//anatomical structure development	--
ENSG00000241468	63.907	68.069	67.69	76.992	50.163	70.895	474.38	501.4	368.85	418	311.67	390.87	ATP5MF	ATP synthase membrane subunit f [Source:HGNC Symbol;Acc:HGNC:848]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02130;K02130;K02130	"GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	"GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:1902600//proton transmembrane transport	--
ENSG00000241476	0	0	0	0	0	0	0	0	0	0	0	0	SSX2	SSX family member 2 [Source:HGNC Symbol;Acc:HGNC:11336]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15625	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000241484	4.185	5.472	4.112	4.421	5.799	5.195	140.85	181	102	110.62	165.42	127.94	ARHGAP8	Rho GTPase activating protein 8 [Source:HGNC Symbol;Acc:HGNC:677]	-	-	-	-	GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0070374//positive regulation of ERK1 and ERK2 cascade	--
ENSG00000241489	0.976	1.108	1.196	0.926	2.01	1.148	92.04	94.81	78.16	72.45	119.79	68.21	IDS	novel protein	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01136;K01136;K01136	-	GO:0003824//catalytic activity;GO:0008484//sulfuric ester hydrolase activity	-	--
ENSG00000241553	39.154	44.585	47.736	46.362	46.732	39.498	1106.95	1261.16	1008.03	961.61	1053.46	791.64	ARPC4	actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05755;K05755;K05755;K05755;K05755;K05755;K05755;K05755;K05755	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0015629//actin cytoskeleton;GO:0035861//site of double-strand break;GO:0042995//cell projection;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0030674//protein-macromolecule adaptor activity;GO:0051015//actin filament binding	GO:0030041//actin filament polymerization;GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0045010//actin nucleation	--
ENSG00000241563	0.239	0	0.245	0	0.375	0.362	4.54	0	3.43	0	6	5	CORT	cortistatin [Source:HGNC Symbol;Acc:HGNC:2257]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05238	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043240//Fanconi anaemia nuclear complex;GO:0045202//synapse;GO:0071821//FANCM-MHF complex	GO:0001664//G protein-coupled receptor binding;GO:0003682//chromatin binding;GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity	GO:0000712//resolution of meiotic recombination intermediates;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0031297//replication fork processing	--
ENSG00000241566	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-24	immunoglobulin kappa variable 2D-24 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5797]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000241595	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP9-4	keratin associated protein 9-4 [Source:HGNC Symbol;Acc:HGNC:18902]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000241598	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-4	keratin associated protein 5-4 [Source:HGNC Symbol;Acc:HGNC:23599]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	-	GO:0031424//keratinization	--
ENSG00000241635	0.041	0.033	0	0.138	0.048	0	2	1.64	0	5	2	0	UGT1A1	UDP glucuronosyltransferase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:12530]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034663//endoplasmic reticulum chaperone complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:0070069//cytochrome complex	GO:0001972//retinoic acid binding;GO:0004857//enzyme inhibitor activity;GO:0005496//steroid binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0001889//liver development;GO:0006629//lipid metabolic process;GO:0006789//bilirubin conjugation;GO:0006805//xenobiotic metabolic process;GO:0006953//acute-phase response;GO:0007584//response to nutrient;GO:0008202//steroid metabolic process;GO:0008210//estrogen metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0014070//response to organic cyclic compound;GO:0031100//animal organ regeneration;GO:0032496//response to lipopolysaccharide;GO:0032870//cellular response to hormone stimulus;GO:0042573//retinoic acid metabolic process;GO:0042594//response to starvation;GO:0043086//negative regulation of catalytic activity;GO:0045471//response to ethanol;GO:0045922//negative regulation of fatty acid metabolic process;GO:0045939//negative regulation of steroid metabolic process;GO:0046483//heterocycle metabolic process;GO:0048545//response to steroid hormone;GO:0051384//response to glucocorticoid;GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation;GO:0070980//biphenyl catabolic process;GO:0071361//cellular response to ethanol;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0071466//cellular response to xenobiotic stimulus;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:2001030//negative regulation of cellular glucuronidation	--
ENSG00000241644	0.471	0.281	0.123	0.305	0.312	0.647	25	15	4	12	14	25	INMT	indolethylamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:6069]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism;ko00450//Selenocompound metabolism	K00562;K00562;K00562	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004790//thioether S-methyltransferase activity;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0016740//transferase activity;GO:0030748//amine N-methyltransferase activity;GO:0102707//S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity	GO:0009308//amine metabolic process;GO:0009636//response to toxic substance;GO:0032259//methylation	--
ENSG00000241685	60.139	64.319	65.418	69.488	64.525	67.322	1973.4	2121.4	1585.41	1689	1788.83	1607.34	ARPC1A	actin related protein 2/3 complex subunit 1A [Source:HGNC Symbol;Acc:HGNC:703]	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0015629//actin cytoskeleton;GO:0035861//site of double-strand break;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0030036//actin cytoskeleton organization;GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation	--
ENSG00000241690	0	0	0	0	0	0	0	0	0	0	0	0	C20orf141	novel protein	-	-	-	-	-	-	-	--
ENSG00000241697	9.231	8.545	6.716	8.614	9.065	7.52	493.03	458.74	264.94	340.78	409.05	292.24	TMEFF1	transmembrane protein with EGF like and two follistatin like domains 1 [Source:HGNC Symbol;Acc:HGNC:11866]	-	-	-	-	GO:0005604//basement membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005102//signaling receptor binding;GO:0005515//protein binding	GO:0008045//motor neuron axon guidance;GO:0009887//animal organ morphogenesis;GO:0009888//tissue development;GO:0016358//dendrite development	--
ENSG00000241755	0	0	0	0	0.14	0	0	0	0	0	1	0	IGKV1-9	immunoglobulin kappa variable 1-9 [Source:HGNC Symbol;Acc:HGNC:5744]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000241794	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2A	small proline rich protein 2A [Source:HGNC Symbol;Acc:HGNC:11261]	-	-	-	-	GO:0001533//cornified envelope;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030141//secretory granule	GO:0005515//protein binding;GO:0008289//lipid binding	GO:0019731//antibacterial humoral response;GO:0031424//keratinization;GO:0048874//host-mediated regulation of intestinal microbiota composition;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000241837	110.256	108.198	108.374	110.763	103.081	106.718	1728	1707	1256	1285.33	1364.05	1217.38	ATP5PO	ATP synthase peripheral stalk subunit OSCP [Source:HGNC Symbol;Acc:HGNC:850]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137	"GO:0000274//mitochondrial proton-transporting ATP synthase, stator stalk;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)"	"GO:0005515//protein binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:1902600//proton transmembrane transport	--
ENSG00000241839	18.366	18.582	22.774	24.789	22.575	22.865	1405.28	1429.16	1287	1405	1459	1272.74	PLEKHO2	pleckstrin homology domain containing O2 [Source:HGNC Symbol;Acc:HGNC:30026]	-	-	-	-	GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen	GO:0005515//protein binding	GO:0071888//macrophage apoptotic process	--
ENSG00000241852	4.234	4.405	3.646	4.745	3.94	3.265	160	184	108.94	143.32	136	98	C8orf58	chromosome 8 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:32233]	-	-	-	-	-	-	-	--
ENSG00000241878	6.466	6.777	6.921	7.869	7.184	7.039	296	337	255	246	264	235	PISD	phosphatidylserine decarboxylase [Source:HGNC Symbol;Acc:HGNC:8999]	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00564//Glycerophospholipid metabolism	K01613;K01613	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0004609//phosphatidylserine decarboxylase activity;GO:0005515//protein binding;GO:0016829//lyase activity;GO:0016831//carboxy-lyase activity	GO:0006629//lipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0010821//regulation of mitochondrion organization;GO:0016540//protein autoprocessing;GO:0035694//mitochondrial protein catabolic process	--
ENSG00000241935	2.146	2.637	1.99	2.47	3.109	2.172	98.28	121.71	68.8	82.47	94	71.97	HOGA1	4-hydroxy-2-oxoglutarate aldolase 1 [Source:HGNC Symbol;Acc:HGNC:25155]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism;ko00630//Glyoxylate and dicarboxylate metabolism	K18123;K18123;K18123	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008700//4-hydroxy-2-oxoglutarate aldolase activity;GO:0016829//lyase activity;GO:0042803//protein homodimerization activity	GO:0009436//glyoxylate catabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0033609//oxalate metabolic process;GO:0042866//pyruvate biosynthetic process;GO:0046487//glyoxylate metabolic process	--
ENSG00000241945	0.174	0	0	0.635	0.376	0	2.18	0	0	5.89	3.98	0	PWP2	PWP2 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:9711]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14558	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0034388//Pwp2p-containing subcomplex of 90S preribosome	GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000028//ribosomal small subunit assembly;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"	--
ENSG00000241962	0.354	0.041	0.05	0	0	0.296	14.31	1.67	1.5	0	0	8.7	MRPL30	"novel protein, C2orf15-MRPL30-novel lincRNA readthrough"	Genetic Information Processing	Translation	ko03010//Ribosome	K02907	-	-	-	--
ENSG00000241973	42.766	42.982	43.621	47.372	45.786	48.023	5464	5630	4320	4190	4903	4470	PI4KA	phosphatidylinositol 4-kinase alpha [Source:HGNC Symbol;Acc:HGNC:8983]	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00888;K00888;K00888	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0070062//extracellular exosome	GO:0000166//nucleotide binding;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0045296//cadherin binding;GO:0052742//phosphatidylinositol kinase activity	GO:0006629//lipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0039694//viral RNA genome replication;GO:0044803//multi-organism membrane organization;GO:0046786//viral replication complex formation and maintenance;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling	--
ENSG00000242019	0	0	0	0	0	0	0	0	0	0	0	0	KIR3DL3	"killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 [Source:HGNC Symbol;Acc:HGNC:16312]"	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K07980;K07980;K07980	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000242028	3.431	4.392	3.461	3.421	1.32	2.726	262.2	309.42	180.64	176.47	104.19	144.81	HYPK	huntingtin interacting protein K [Source:HGNC Symbol;Acc:HGNC:18418]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0047485//protein N-terminus binding	GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization	--
ENSG00000242076	0	0	0	0	3.735	0	0	0	0	0	25	0	IGKV1-33	immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding;GO:0042802//identical protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000242110	6.017	6.12	5.778	5.773	6.322	6.621	249	278	161	181	228	203	AMACR	alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451]	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04146//Peroxisome;ko00120//Primary bile acid biosynthesis	K01796;K01796;K01796	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0003824//catalytic activity;GO:0005102//signaling receptor binding;GO:0008111//alpha-methylacyl-CoA racemase activity;GO:0016853//isomerase activity	GO:0006631//fatty acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase	--
ENSG00000242114	5.665	5.933	6.584	8.714	6.631	7.473	115	128	112.5	145	116	113.11	MTFP1	mitochondrial fission process 1 [Source:HGNC Symbol;Acc:HGNC:26945]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0000266//mitochondrial fission;GO:0006915//apoptotic process;GO:0007005//mitochondrion organization;GO:0014850//response to muscle activity	--
ENSG00000242120	0	0	0	0	0	0	0	0	0	0	0	0	MDFIC2	MyoD family inhibitor domain containing 2 [Source:HGNC Symbol;Acc:HGNC:53442]	-	-	-	-	-	-	-	--
ENSG00000242173	1.531	1.542	2.58	2.026	2.31	2.274	28	31	33	30	33	31	ARHGDIG	Rho GDP dissociation inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:680]	Organismal Systems;Organismal Systems	Nervous system;Excretory system	ko04722//Neurotrophin signaling pathway;ko04962//Vasopressin-regulated water reabsorption	K12462;K12462	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle	GO:0005092//GDP-dissociation inhibitor activity;GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity	GO:0001835//blastocyst hatching;GO:0007162//negative regulation of cell adhesion;GO:0007266//Rho protein signal transduction;GO:0032880//regulation of protein localization;GO:0050790//regulation of catalytic activity	--
ENSG00000242220	0	0	0.267	0	0.12	0.344	0	0	3.04	0	1.57	3.86	TCP10L	t-complex 10 like [Source:HGNC Symbol;Acc:HGNC:11657]	-	-	-	-	GO:0005634//nucleus;GO:0005814//centriole	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0043621//protein self-association;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003352//regulation of cilium movement	--
ENSG00000242221	0	0	0	0	0	0	0	0	0	0	0	0	PSG2	pregnancy specific beta-1-glycoprotein 2 [Source:HGNC Symbol;Acc:HGNC:9519]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0003674//molecular_function	GO:0007565//female pregnancy;GO:0016477//cell migration	--
ENSG00000242247	16.253	15.235	14.644	11.929	11.972	14.306	896	855	612	500	560	589	ARFGAP3	ADP ribosylation factor GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:661]	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K12493	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle;GO:0050790//regulation of catalytic activity	--
ENSG00000242252	0	0	0	0	0	0	0	0	0	0	0	0	BGLAP	bone gamma-carboxyglutamate protein [Source:HGNC Symbol;Acc:HGNC:1043]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K22609	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005796//Golgi lumen;GO:0030425//dendrite;GO:0031982//vesicle;GO:0042995//cell projection;GO:0043204//perikaryon	GO:0005198//structural molecule activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008147//structural constituent of bone;GO:0046848//hydroxyapatite binding;GO:0046872//metal ion binding	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0002076//osteoblast development;GO:0007155//cell adhesion;GO:0007568//aging;GO:0007569//cell aging;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009629//response to gravity;GO:0010035//response to inorganic substance;GO:0010043//response to zinc ion;GO:0014070//response to organic cyclic compound;GO:0014823//response to activity;GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0031214//biomineral tissue development;GO:0031667//response to nutrient levels;GO:0032571//response to vitamin K;GO:0033280//response to vitamin D;GO:0033574//response to testosterone;GO:0033594//response to hydroxyisoflavone;GO:0042476//odontogenesis;GO:0043627//response to estrogen;GO:0045124//regulation of bone resorption;GO:0045471//response to ethanol;GO:0045670//regulation of osteoclast differentiation;GO:0051384//response to glucocorticoid;GO:0060348//bone development;GO:0071305//cellular response to vitamin D;GO:0071363//cellular response to growth factor stimulus;GO:1900076//regulation of cellular response to insulin stimulus	--
ENSG00000242259	13.444	14.617	13.009	11.965	11.279	10.616	640.76	691	480.48	433.63	500.72	425.95	C22orf39	chromosome 22 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:27012]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000242265	12.783	11.977	13.365	13.333	13.273	14.07	1646	1625	1284	1236	1379	1320	PEG10	paternally expressed 10 [Source:HGNC Symbol;Acc:HGNC:14005]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:1903561//extracellular vesicle	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0051028//mRNA transport;GO:0051260//protein homooligomerization;GO:0110077//vesicle-mediated intercellular transport	--
ENSG00000242362	0	0	0	0	0	0	0	0	0	0	0	0	CT47A2	cancer/testis antigen family 47 member A2 [Source:HGNC Symbol;Acc:HGNC:33283]	-	-	-	-	-	-	-	--
ENSG00000242366	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A8	UDP glucuronosyltransferase family 1 member A8 [Source:HGNC Symbol;Acc:HGNC:12540]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001972//retinoic acid binding;GO:0004857//enzyme inhibitor activity;GO:0005496//steroid binding;GO:0005504//fatty acid binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0009804//coumarin metabolic process;GO:0042573//retinoic acid metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0045922//negative regulation of fatty acid metabolic process;GO:0045939//negative regulation of steroid metabolic process;GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation	--
ENSG00000242371	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-39	immunoglobulin kappa variable 1-39 [Source:HGNC Symbol;Acc:HGNC:5740]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000242372	39.642	44.823	46.729	55.406	46.724	47.126	882	1001	764	914	878	763	EIF6	eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:HGNC:6159]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K03264	"GO:0005634//nucleus;GO:0005638//lamin filament;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0030687//preribosome, large subunit precursor;GO:0070062//extracellular exosome"	GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0043023//ribosomal large subunit binding	GO:0000054//ribosomal subunit export from nucleus;GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006110//regulation of glycolytic process;GO:0006412//translation;GO:0006413//translational initiation;GO:0032868//response to insulin;GO:0035195//gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0042254//ribosome biogenesis;GO:0042256//mature ribosome assembly;GO:0042273//ribosomal large subunit biogenesis;GO:0042304//regulation of fatty acid biosynthetic process;GO:0045652//regulation of megakaryocyte differentiation;GO:0045727//positive regulation of translation;GO:1902626//assembly of large subunit precursor of preribosome;GO:2000377//regulation of reactive oxygen species metabolic process	--
ENSG00000242389	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1E	RNA binding motif protein Y-linked family 1 member E [Source:HGNC Symbol;Acc:HGNC:23916]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000242419	0.173	0.143	0.491	0.07	0.295	0.273	10	14.21	13	3	24.65	19.59	PCDHGC4	"protocadherin gamma subfamily C, 4 [Source:HGNC Symbol;Acc:HGNC:8717]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0043524//negative regulation of neuron apoptotic process;GO:0050808//synapse organization	--
ENSG00000242441	0.269	0.014	0.225	0.241	0.146	0.545	8.8	0.17	5.58	6	2.77	7.84	GTF2A1L	general transcription factor IIA subunit 1 like [Source:HGNC Symbol;Acc:HGNC:30727]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05203//Viral carcinogenesis;ko03022//Basal transcription factors	K03122;K03122	GO:0005634//nucleus;GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050890//cognition"	--
ENSG00000242472	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ5	immunoglobulin heavy joining 5 [Source:HGNC Symbol;Acc:HGNC:5539]	-	-	-	-	-	-	-	--
ENSG00000242485	48.741	43.853	48.646	49.787	39.73	45.791	715	641	524	536	488	483	MRPL20	mitochondrial ribosomal protein L20 [Source:HGNC Symbol;Acc:HGNC:14478]	Genetic Information Processing	Translation	ko03010//Ribosome	K02887	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0043229//intracellular organelle	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding	GO:0000027//ribosomal large subunit assembly;GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000242498	6.174	4.389	3.963	3.674	4.187	3.698	633.48	650.31	460.64	408.8	540.39	349.01	ARPIN	actin related protein 2/3 complex inhibitor [Source:HGNC Symbol;Acc:HGNC:28782]	-	-	-	-	GO:0030027//lamellipodium;GO:0042995//cell projection	GO:0005515//protein binding	GO:0030336//negative regulation of cell migration;GO:0033058//directional locomotion;GO:0051126//negative regulation of actin nucleation;GO:2000393//negative regulation of lamellipodium morphogenesis	--
ENSG00000242515	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A10	UDP glucuronosyltransferase family 1 member A10 [Source:HGNC Symbol;Acc:HGNC:12531]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005080//protein kinase C binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0045922//negative regulation of fatty acid metabolic process;GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:2001030//negative regulation of cellular glucuronidation	--
ENSG00000242534	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-28	immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000242550	0.04	0	0	0	0	0	1	0	0	0	0	0	SERPINB10	serpin family B member 10 [Source:HGNC Symbol;Acc:HGNC:8942]	Human Diseases	Infectious disease: parasitic	ko05146//Amoebiasis	K13963	GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0043066//negative regulation of apoptotic process	--
ENSG00000242574	0	0.036	0.531	0.097	0.381	0.295	0	1	10	2	9	6	HLA-DMB	"major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0042613//MHC class II protein complex;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0023026//MHC class II protein complex binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002399//MHC class II protein complex assembly;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042102//positive regulation of T cell proliferation;GO:0050870//positive regulation of T cell activation;GO:2001190//positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	--
ENSG00000242580	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-43	immunoglobulin kappa variable 1D-43 [Source:HGNC Symbol;Acc:HGNC:5758]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000242612	4.972	4.546	5.165	4.859	5.415	5.291	155.98	147	86	115	118.98	123	DECR2	"2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754]"	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13237	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol	"GO:0005515//protein binding;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0016491//oxidoreductase activity;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity"	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0009062//fatty acid catabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase	--
ENSG00000242616	36.365	35.533	37.636	39.232	31.818	42.84	905.89	889.72	692.45	723.93	669.64	776.5	GNG10	G protein subunit gamma 10 [Source:HGNC Symbol;Acc:HGNC:4402]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Cancer: overview;Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Substance dependence;Nervous system;Signal transduction;Nervous system;Endocrine system;Nervous system;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko05034//Alcoholism;ko04723//Retrograde endocannabinoid signaling;ko04371//Apelin signaling pathway;ko04728//Dopaminergic synapse;ko04926//Relaxin signaling pathway;ko04724//Glutamatergic synapse;ko04725//Cholinergic synapse;ko04726//Serotonergic synapse;ko04713//Circadian entrainment;ko05032//Morphine addiction;ko04727//GABAergic synapse	K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545;K04545	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000242689	0.101	0.028	0	0.087	0	0.102	4	1.1	0	2.54	0	2.92	CNTF	ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway	K05420;K05420	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0030424//axon	GO:0005125//cytokine activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0044877//protein-containing complex binding	GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043524//negative regulation of neuron apoptotic process;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0046668//regulation of retinal cell programmed cell death;GO:0048143//astrocyte activation;GO:0048644//muscle organ morphogenesis;GO:0048666//neuron development;GO:0048680//positive regulation of axon regeneration;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway	--
ENSG00000242715	0.647	0.873	0.56	0.709	0.561	0.609	32.75	39	21	25	13.46	22	CCDC169	coiled-coil domain containing 169 [Source:HGNC Symbol;Acc:HGNC:34361]	-	-	-	-	-	-	-	--
ENSG00000242732	9.144	9.856	10.228	9.764	9.734	10.041	814	880	669	637	729	649	RTL5	retrotransposon Gag like 5 [Source:HGNC Symbol;Acc:HGNC:29430]	-	-	-	-	-	-	-	--
ENSG00000242766	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-17	immunoglobulin kappa variable 1D-17 [Source:HGNC Symbol;Acc:HGNC:5749]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000242802	12.871	13.917	11.637	12.706	13.008	14.649	706	832	554	551	598	652	AP5Z1	adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0016607//nuclear speck;GO:0030119//AP-type membrane coat adaptor complex;GO:0044599//AP-5 adaptor complex	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport	--
ENSG00000242852	0.882	0.914	0.813	0.718	0.629	1.028	89.54	93.34	61	54	54	76	ZNF709	zinc finger protein 709 [Source:HGNC Symbol;Acc:HGNC:20629]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000242866	0.155	0.267	0.282	0.089	0.027	0.128	11	17	18	2.5	2	10	STRC	stereocilin [Source:HGNC Symbol;Acc:HGNC:16035]	-	-	-	-	GO:0005929//cilium;GO:0009986//cell surface;GO:0032420//stereocilium;GO:0032426//stereocilium tip;GO:0042995//cell projection;GO:0060091//kinocilium;GO:0110165//cellular anatomical entity	-	GO:0007160//cell-matrix adhesion;GO:0007605//sensory perception of sound;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060088//auditory receptor cell stereocilium organization	--
ENSG00000242875	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1B	RNA binding motif protein Y-linked family 1 member B [Source:HGNC Symbol;Acc:HGNC:23914]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	"GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0008380//RNA splicing;GO:0008584//male gonad development;GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000242887	0	0	0	0	0	0	0	0	0	0	0	0	IGHJ3	immunoglobulin heavy joining 3 [Source:HGNC Symbol;Acc:HGNC:5536]	-	-	-	-	-	-	-	--
ENSG00000242950	0.068	0.017	0	0.023	0.041	0.069	4	1	0	1	2	3	ERVW-1	"endogenous retrovirus group W member 1, envelope [Source:HGNC Symbol;Acc:HGNC:13525]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0000768//syncytium formation by plasma membrane fusion;GO:0006949//syncytium formation;GO:0007520//myoblast fusion;GO:0009653//anatomical structure morphogenesis	--
ENSG00000243056	8.768	11.616	9.684	7.656	10.943	12.525	126.03	167.83	102.81	81.52	132.89	131	EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex	GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0030371//translation repressor activity	GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0045947//negative regulation of translational initiation	--
ENSG00000243063	0	0	0	0	0	0	0	0	0	0	0	0	IGKV3-7	immunoglobulin kappa variable 3-7 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5821]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000243073	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF4	PRAME family member 4 [Source:HGNC Symbol;Acc:HGNC:31971]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000243130	0	0	0	0	0	0	0	0	0	0	0	0	PSG11	pregnancy specific beta-1-glycoprotein 11 [Source:HGNC Symbol;Acc:HGNC:9516]	-	-	-	-	GO:0005576//extracellular region	-	GO:0007565//female pregnancy	--
ENSG00000243137	0	0	0	0	0	0	0	0	0	0	0	0	PSG4	pregnancy specific beta-1-glycoprotein 4 [Source:HGNC Symbol;Acc:HGNC:9521]	-	-	-	-	GO:0005576//extracellular region	-	GO:0007565//female pregnancy	--
ENSG00000243147	19.26	16.562	17.429	14.622	10.957	17.145	178.48	155	119	100	87	113	MRPL33	mitochondrial ribosomal protein L33 [Source:HGNC Symbol;Acc:HGNC:14487]	Genetic Information Processing	Translation	ko03010//Ribosome	K02913	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000243156	9.16	7.681	7.153	9.033	6.962	8.993	1100	1019	799	832	941	851	MICAL3	"microtubule associated monooxygenase, calponin and LIM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24694]"	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0030496//midbody;GO:0042995//cell projection;GO:0045171//intercellular bridge;GO:0090543//Flemming body	"GO:0003779//actin binding;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0031267//small GTPase binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding;GO:0071949//FAD binding"	GO:0006887//exocytosis;GO:0007010//cytoskeleton organization;GO:0007049//cell cycle;GO:0030042//actin filament depolymerization;GO:0051301//cell division	--
ENSG00000243207	0.577	0.666	1.353	0.798	1.155	0.419	31.83	36.95	55.15	32.63	53.88	16.84	PPAN-P2RY11	PPAN-P2RY11 readthrough [Source:HGNC Symbol;Acc:HGNC:33526]	-	-	-	-	GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0019843//rRNA binding;GO:0030594//neurotransmitter receptor activity;GO:0045031//G protein-coupled ATP receptor activity	GO:0006364//rRNA processing;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0023041//neuronal signal transduction;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway	--
ENSG00000243232	5.426	5.478	4.654	6.336	5.858	6.241	644.37	653.84	408.16	550.6	587.72	539.24	PCDHAC2	"protocadherin alpha subfamily C, 2 [Source:HGNC Symbol;Acc:HGNC:8677]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000243238	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2-30	immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000243244	18.061	14.039	16.008	12.067	13.519	14.208	2078.17	1624.71	1359.71	1028	1277.79	1172.23	STON1	stonin 1 [Source:HGNC Symbol;Acc:HGNC:17003]	-	-	-	-	GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle	GO:0035615//clathrin adaptor activity	GO:0006897//endocytosis;GO:0016192//vesicle-mediated transport;GO:0030100//regulation of endocytosis;GO:0048488//synaptic vesicle endocytosis	--
ENSG00000243264	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-29	immunoglobulin kappa variable 2D-29 [Source:HGNC Symbol;Acc:HGNC:5800]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000243279	32.798	32.185	33.136	32.86	35.637	34.683	847	835.59	635	624	774	640.38	PRAF2	PRA1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:28911]	-	-	-	-	GO:0005768//endosome;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0015031//protein transport;GO:0015813//L-glutamate transmembrane transport	--
ENSG00000243284	0	0	0	0	0	0	0	0	0	0	0	0	VSIG8	V-set and immunoglobulin domain containing 8 [Source:HGNC Symbol;Acc:HGNC:32063]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding	-	--
ENSG00000243290	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1-12	immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000243317	32.731	30.428	32.194	27.558	26.318	36.967	1658	1548	1201	1042	1135	1373	STMP1	short transmembrane mitochondrial protein 1 [Source:HGNC Symbol;Acc:HGNC:41909]	-	-	-	-	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005746//mitochondrial respirasome;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0002376//immune system process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0045087//innate immune response;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly	--
ENSG00000243335	6.141	6.4	6.88	6.551	6.325	7.412	617.8	645.97	509	481	537.64	468.8	KCTD7	potassium channel tetramerization domain containing 7 [Source:HGNC Symbol;Acc:HGNC:21957]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0030007//cellular potassium ion homeostasis;GO:0032411//positive regulation of transporter activity;GO:0051260//protein homooligomerization;GO:0060081//membrane hyperpolarization;GO:0090461//glutamate homeostasis	--
ENSG00000243364	4.592	6.175	3.94	6.071	4.741	4.258	115	159	75	113	102	79	EFNA4	ephrin A4 [Source:HGNC Symbol;Acc:HGNC:3224]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031226//intrinsic component of plasma membrane	GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0046875//ephrin receptor binding	GO:0007267//cell-cell signaling;GO:0007411//axon guidance;GO:0048013//ephrin receptor signaling pathway	--
ENSG00000243414	0.476	0.265	0.222	0.216	0.056	0.567	31.63	17.72	10.91	10.63	3.17	27.39	TICAM2	toll like receptor adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:21354]	Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Cardiovascular disease;Signal transduction;Cell growth and death;Infectious disease: viral;Immune system;Cancer: overview;Infectious disease: bacterial	ko05417//Lipid and atherosclerosis;ko04064//NF-kappa B signaling pathway;ko04217//Necroptosis;ko05161//Hepatitis B;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis	K05409;K05409;K05409;K05409;K05409;K05409;K05409	GO:0001891//phagocytic cup;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030667//secretory granule membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0042995//cell projection	GO:0003953//NAD+ nucleosidase activity;GO:0005515//protein binding	GO:0002376//immune system process;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0071222//cellular response to lipopolysaccharide;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway	--
ENSG00000243449	39.03	41.629	46.017	68.273	51.275	53.245	345	371	302	448	385	344	C4orf48	chromosome 4 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:34437]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000243466	0	0	0	0	0.429	0	0	0	0	0	4	0	IGKV1-5	immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000243477	4.41	4.214	4.425	5.122	5.149	3.941	119	132	89	105	117	74.59	NAA80	"N-alpha-acetyltransferase 80, NatH catalytic subunit [Source:HGNC Symbol;Acc:HGNC:30252]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:1905502//acetyl-CoA binding	GO:0006473//protein acetylation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0017190//N-terminal peptidyl-aspartic acid acetylation;GO:0018002//N-terminal peptidyl-glutamic acid acetylation;GO:0030047//actin modification	--
ENSG00000243480	0	0	0	0	0	0	0	0	0	0	0	0	AMY2A	amylase alpha 2A [Source:HGNC Symbol;Acc:HGNC:477]	Metabolism;Organismal Systems;Organismal Systems;Organismal Systems;Metabolism	Global and overview maps;Digestive system;Digestive system;Digestive system;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko04970//Salivary secretion;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism	K01176;K01176;K01176;K01176;K01176	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	"GO:0003824//catalytic activity;GO:0004556//alpha-amylase activity;GO:0005509//calcium ion binding;GO:0016160//amylase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0031404//chloride ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0103025//alpha-amylase activity (releasing maltohexaose)"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process;GO:0016052//carbohydrate catabolic process;GO:0044245//polysaccharide digestion	--
ENSG00000243489	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-11	keratin associated protein 10-11 [Source:HGNC Symbol;Acc:HGNC:20528]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000243501	0	0	0.1	0	0	0	0	0	2.5	0	0	0	KHDC1	novel protein	-	-	-	-	GO:0110165//cellular anatomical entity	GO:0003723//RNA binding	-	--
ENSG00000243509	0.456	0.295	0.249	0.171	0.712	0.232	10.78	7	4.35	3	14.22	4	TNFRSF6B	TNF receptor superfamily member 6b [Source:HGNC Symbol;Acc:HGNC:11921]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05143	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process	--
ENSG00000243543	0	0	0	0	0	0	0	0	0	0	0	0	WFDC6	WAP four-disulfide core domain 6 [Source:HGNC Symbol;Acc:HGNC:16164]	-	-	-	-	GO:0005576//extracellular region	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0043086//negative regulation of catalytic activity;GO:0052547//regulation of peptidase activity	--
ENSG00000243566	602.402	618.492	799.339	1392.779	1241.186	1217.476	16329	17127	16022	28328	29001	24197	UPK3B	uroplakin 3B [Source:HGNC Symbol;Acc:HGNC:21444]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0010629//negative regulation of gene expression	--
ENSG00000243627	0	0	0	0	0	0	0	0	0	0	0	0	SMIM34	small integral membrane protein 34 [Source:HGNC Symbol;Acc:HGNC:39601]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000243641	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000243646	12.274	13.324	13.845	13.441	12.249	13.628	488.77	541.13	398	391.48	395.46	394.13	IL10RB	interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Infectious disease: parasitic;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05152//Tuberculosis;ko05163//Human cytomegalovirus infection;ko04630//JAK-STAT signaling pathway;ko05145//Toxoplasmosis;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05135;K05135;K05135;K05135;K05135;K05135	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032002//interleukin-28 receptor complex	GO:0004896//cytokine receptor activity;GO:0004920//interleukin-10 receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity	GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0038196//type III interferon signaling pathway;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0051607//defense response to virus;GO:0098586//cellular response to virus;GO:1901857//positive regulation of cellular respiration	--
ENSG00000243649	23.782	31.153	25.209	18.791	21.126	21.481	1008.59	1134	804.78	542.84	647.54	635	CFB	complement factor B [Source:HGNC Symbol;Acc:HGNC:1037]	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01335;K01335;K01335	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001848//complement binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0045087//innate immune response"	--
ENSG00000243660	1.406	1.419	1.798	1.006	1.756	0.965	52	44	37	34	43	31	ZNF487	zinc finger protein 487 [Source:HGNC Symbol;Acc:HGNC:23488]	-	-	-	-	-	-	"GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000243667	4.094	4.396	4.953	4.112	4.13	4.921	193.06	209.74	172.22	140	164.41	179.04	DNAAF10	dynein axonemal assembly factor 10 [Source:HGNC Symbol;Acc:HGNC:25176]	-	-	-	-	GO:0005737//cytoplasm;GO:0120293//dynein axonemal particle;GO:1990062//RPAP3/R2TP/prefoldin-like complex	GO:0005515//protein binding;GO:0043130//ubiquitin binding	GO:0006915//apoptotic process;GO:0050821//protein stabilization;GO:0070286//axonemal dynein complex assembly	--
ENSG00000243678	224.49	234.487	235.794	253.398	227.966	231.198	3237.43	3388.58	2504.73	2714.15	2779.47	2423.65	NME2	NME/NM23 nucleoside diphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:7850]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00940;K00940;K00940;K00940	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0034774//secretory granule lumen;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0071944//cell periphery;GO:1904813//ficolin-1-rich granule lumen	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004673//protein histidine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019003//GDP binding;GO:0046872//metal ion binding;GO:0051880//G-quadruplex DNA binding	"GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0009117//nucleotide metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0018106//peptidyl-histidine phosphorylation;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045618//positive regulation of keratinocyte differentiation;GO:0045682//regulation of epidermis development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050679//positive regulation of epithelial cell proliferation;GO:0055086//nucleobase-containing small molecule metabolic process"	Others
ENSG00000243696	0.083	0.131	0.089	0.058	0.226	0.176	9.67	15.41	7.65	5	22.36	15	MUSTN1	novel MUSTN1-ITIH4 readthrough	-	-	-	-	GO:0005634//nucleus	-	GO:0002062//chondrocyte differentiation;GO:0035988//chondrocyte proliferation;GO:0042246//tissue regeneration	--
ENSG00000243708	0	0.128	0.742	0	0	0.221	0	7.2	30.66	0	0	9.95	PLA2G4B	phospholipase A2 group IVB [Source:HGNC Symbol;Acc:HGNC:9036]	Metabolism;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Metabolism;Organismal Systems;Metabolism;Environmental Information Processing;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Signal transduction;Signal transduction;Immune system;Cell growth and death;Endocrine system;Immune system;Circulatory system;Immune system;Nervous system;Nervous system;Cancer: overview;Sensory system;Lipid metabolism;Endocrine system;Lipid metabolism;Signal transduction;Nervous system;Endocrine system;Lipid metabolism;Lipid metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04217//Necroptosis;ko04921//Oxytocin signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04270//Vascular smooth muscle contraction;ko04611//Platelet activation;ko04724//Glutamatergic synapse;ko04726//Serotonergic synapse;ko05231//Choline metabolism in cancer;ko04750//Inflammatory mediator regulation of TRP channels;ko00564//Glycerophospholipid metabolism;ko04912//GnRH signaling pathway;ko00590//Arachidonic acid metabolism;ko04370//VEGF signaling pathway;ko04730//Long-term depression;ko04913//Ovarian steroidogenesis;ko00565//Ether lipid metabolism;ko00591//Linoleic acid metabolism;ko00592//alpha-Linolenic acid metabolism	K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342;K16342	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005768//endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0031966//mitochondrial membrane	GO:0004620//phospholipase activity;GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008970//phospholipase A1 activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0102545//phosphatidyl phospholipase B activity	GO:0006629//lipid metabolic process;GO:0006954//inflammatory response;GO:0007567//parturition;GO:0009395//phospholipid catabolic process;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0019722//calcium-mediated signaling;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046475//glycerophospholipid catabolic process	--
ENSG00000243709	0	0.03	0	0.08	0.038	0	0	1.01	0	2	1.08	0	LEFTY1	left-right determination factor 1 [Source:HGNC Symbol;Acc:HGNC:6552]	Cellular Processes;Environmental Information Processing	Cellular community - eukaryotes;Signal transduction	ko04550//Signaling pathways regulating pluripotency of stem cells;ko04350//TGF-beta signaling pathway	K04668;K04668	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0008083//growth factor activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0003007//heart morphogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007368//determination of left/right symmetry;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction	--
ENSG00000243710	0.595	0.81	0.43	0.291	0.208	0.447	44	41	12	12	10	8	CFAP57	cilia and flagella associated protein 57 [Source:HGNC Symbol;Acc:HGNC:26485]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000243716	19.541	14.588	17.051	20.852	21.605	18.531	861.93	657.84	558.06	620.99	818.71	668.08	NPIPB5	nuclear pore complex interacting protein family member B5 [Source:HGNC Symbol;Acc:HGNC:37233]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000243725	7.122	8.048	8.704	8.53	6.35	8.319	348.02	395.3	314.13	308.78	262.16	295.79	TTC4	tetratricopeptide repeat domain 4 [Source:HGNC Symbol;Acc:HGNC:12394]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0051879//Hsp90 protein binding	GO:0002376//immune system process;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000243729	0	0	0	0	0	0	0	0	0	0	0	0	OR5V1	olfactory receptor family 5 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:13972]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000243749	20.615	20.264	22.485	22.681	21.336	18.999	394.25	389.53	317.59	321.3	344.72	264.37	TMEM35B	transmembrane protein 35B [Source:HGNC Symbol;Acc:HGNC:40021]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000243772	0	0	0	0	0	0	0	0	0	0	0	0	KIR2DL3	"killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 [Source:HGNC Symbol;Acc:HGNC:6331]"	Organismal Systems;Organismal Systems;Human Diseases	Immune system;Immune system;Immune disease	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation;ko05332//Graft-versus-host disease	K07981;K07981;K07981	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003823//antigen binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding	GO:0006955//immune response	--
ENSG00000243789	3.751	3.117	6.237	2.83	4.562	3.694	109.62	90.86	120.21	59.85	108.69	72.68	JMJD7	jumonji domain containing 7 [Source:HGNC Symbol;Acc:HGNC:34397]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0004175//endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0004497//monooxygenase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0016491//oxidoreductase activity;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0016787//hydrolase activity;GO:0035064//methylated histone binding;GO:0046872//metal ion binding;GO:0106155//peptidyl-lysine 3-dioxygenase activity	GO:0006508//proteolysis;GO:0018126//protein hydroxylation	--
ENSG00000243811	0.025	0	0.052	0	0.029	0	1	0	2	0	1	0	APOBEC3D	apolipoprotein B mRNA editing enzyme catalytic subunit 3D [Source:HGNC Symbol;Acc:HGNC:17354]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016554//cytidine to uridine editing;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000243896	0.842	1.186	1	0.821	0.886	0.738	36	39	30	26	32	19	OR2A7	olfactory receptor family 2 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:8234]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000243910	0	0	0	0	0.041	0	0	0	0	0	1	0	TUBA4B	tubulin alpha 4b [Source:HGNC Symbol;Acc:HGNC:18637]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes;Cell growth and death;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04530//Tight junction;ko04210//Apoptosis;ko04540//Gap junction	K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374;K07374	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007017//microtubule-based process;GO:0008150//biological_process	--
ENSG00000243927	83.895	85.986	98.198	78.819	71.639	112.291	1620.08	1669	1400.52	1127.43	1168.78	1577.76	MRPS6	mitochondrial ribosomal protein S6 [Source:HGNC Symbol;Acc:HGNC:14051]	Genetic Information Processing	Translation	ko03010//Ribosome	K02990	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0070181//small ribosomal subunit rRNA binding	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000243943	17.027	17.827	17.544	14.897	16.754	14.229	1242	1310	940	802	1028	752	ZNF512	zinc finger protein 512 [Source:HGNC Symbol;Acc:HGNC:29380]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	zf-C2H2
ENSG00000243955	3.878	4.686	2.412	2.191	1.546	1.306	97.98	119	45	41	33	24	GSTA1	glutathione S-transferase alpha 1 [Source:HGNC Symbol;Acc:HGNC:4626]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0004769//steroid delta-isomerase activity;GO:0005504//fatty acid binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016740//transferase activity;GO:0016853//isomerase activity	GO:0006629//lipid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0030855//epithelial cell differentiation;GO:0043651//linoleic acid metabolic process;GO:0098869//cellular oxidant detoxification;GO:1901687//glutathione derivative biosynthetic process	--
ENSG00000243978	0.231	0.22	0.212	0.125	0.208	0.114	25	24	17	10	19	9	RTL9	retrotransposon Gag like 9 [Source:HGNC Symbol;Acc:HGNC:29245]	-	-	-	-	-	-	-	--
ENSG00000243989	30.215	33.612	30.573	52.991	44.311	45.891	864.72	977.67	655.49	1138.28	1086.16	967.49	ACY1	aminoacylase 1 [Source:HGNC Symbol;Acc:HGNC:177]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Global and overview maps	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00220//Arginine biosynthesis;ko01210//2-Oxocarboxylic acid metabolism	K14677;K14677;K14677;K14677	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004046//aminoacylase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006520//cellular amino acid metabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000244005	11.674	10.639	14.453	16.708	15.817	15.438	428	377	412	396	424	373	NFS1	NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:HGNC:15910]	Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Metabolism of cofactors and vitamins;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00730//Thiamine metabolism;ko04122//Sulfur relay system	K04487;K04487;K04487	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:1990229//iron-sulfur cluster assembly complex	GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0030170//pyridoxal phosphate binding;GO:0031071//cysteine desulfurase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding	GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0016226//iron-sulfur cluster assembly;GO:0018283//iron incorporation into metallo-sulfur cluster;GO:0044571//[2Fe-2S] cluster assembly	--
ENSG00000244020	0	0	0	0	0	0	0	0	0	0	0	0	MT1HL1	metallothionein 1H like 1 [Source:HGNC Symbol;Acc:HGNC:31864]	Organismal Systems	Digestive system	ko04978//Mineral absorption	K14739	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006882//cellular zinc ion homeostasis;GO:0010273//detoxification of copper ion;GO:0071276//cellular response to cadmium ion;GO:0071280//cellular response to copper ion;GO:0071294//cellular response to zinc ion	--
ENSG00000244025	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-3	keratin associated protein 19-3 [Source:HGNC Symbol;Acc:HGNC:18938]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000244038	110.442	114.758	107.867	117.043	113.033	102.772	4508	4711	3254	3554	3914	3053	DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:2728]	Metabolism;Genetic Information Processing;Metabolism;Metabolism	"Global and overview maps;Folding, sorting and degradation;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism"	ko01100//Metabolic pathways;ko04141//Protein processing in endoplasmic reticulum;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K12670;K12670;K12670;K12670	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035577//azurophil granule membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding;GO:0008047//enzyme activator activity	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0031647//regulation of protein stability;GO:0034097//response to cytokine;GO:0042110//T cell activation;GO:0050790//regulation of catalytic activity	--
ENSG00000244045	6.29	4.619	6.425	8.848	6.44	6.673	294	290	228	253	257	224	TMEM199	transmembrane protein 199 [Source:HGNC Symbol;Acc:HGNC:18085]	-	-	-	-	GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030663//COPI-coated vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0005515//protein binding	GO:0006879//cellular iron ion homeostasis;GO:0007042//lysosomal lumen acidification;GO:0036295//cellular response to increased oxygen levels;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:1905146//lysosomal protein catabolic process	--
ENSG00000244057	0	0	0	0	0	0	0	0	0	0	0	0	LCE3C	late cornified envelope 3C [Source:HGNC Symbol;Acc:HGNC:16612]	-	-	-	-	-	GO:0005515//protein binding	GO:0008544//epidermis development;GO:0031424//keratinization;GO:0031640//killing of cells of other organism;GO:0050829//defense response to Gram-negative bacterium;GO:0050830//defense response to Gram-positive bacterium	--
ENSG00000244067	0.08	0.236	0.107	0	0	0.163	2.02	6	2	0	0	3	GSTA2	glutathione S-transferase alpha 2 [Source:HGNC Symbol;Acc:HGNC:4627]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0030855//epithelial cell differentiation	--
ENSG00000244094	0	0	0	0	0	0	0	0	0	0	0	0	SPRR2F	small proline rich protein 2F [Source:HGNC Symbol;Acc:HGNC:11266]	-	-	-	-	GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization	--
ENSG00000244115	5.203	5.304	2.764	4.012	3.907	4.125	156.28	160.12	61.31	89.25	99.13	90.14	DNAJC25-GNG10	DNAJC25-GNG10 readthrough [Source:HGNC Symbol;Acc:HGNC:37501]	-	-	-	-	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000244116	0	0	0	0	1.024	0	0	0	0	0	7	0	IGKV2-28	immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000244122	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A7	UDP glucuronosyltransferase family 1 member A7 [Source:HGNC Symbol;Acc:HGNC:12539]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001972//retinoic acid binding;GO:0004857//enzyme inhibitor activity;GO:0005080//protein kinase C binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008210//estrogen metabolic process;GO:0009804//coumarin metabolic process;GO:0042573//retinoic acid metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation	--
ENSG00000244165	1.42	1.48	1.913	2.49	1.628	2.463	52.68	55.17	52.39	68.4	51.02	66.47	P2RY11	purinergic receptor P2Y11 [Source:HGNC Symbol;Acc:HGNC:8540]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K08387	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0038023//signaling receptor activity;GO:0045031//G protein-coupled ATP receptor activity	GO:0006952//defense response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0023041//neuronal signal transduction;GO:0035589//G protein-coupled purinergic nucleotide receptor signaling pathway;GO:0071318//cellular response to ATP	--
ENSG00000244187	23.903	22.353	25.441	28.625	25.708	25.825	415.97	390.99	326.99	368.99	377.97	327	TMEM141	transmembrane protein 141 [Source:HGNC Symbol;Acc:HGNC:28211]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000244219	0.185	0.071	0.439	0.063	0	0.207	4	2	7	1	0	3.25	TMEM225B	transmembrane protein 225B [Source:HGNC Symbol;Acc:HGNC:53075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0010923//negative regulation of phosphatase activity	--
ENSG00000244234	0	0	0	0	0	0	0	0	0	0	0	0	GMCL2	"germ cell-less 2, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:19717]"	-	-	-	-	GO:0005634//nucleus;GO:0016363//nuclear matrix	GO:0005515//protein binding;GO:0097602//cullin family protein binding	GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation	--
ENSG00000244242	1.211	1.012	0.81	0.827	1.052	1.312	94.14	79.32	46.82	47.76	69.49	74.61	IFITM10	interferon induced transmembrane protein 10 [Source:HGNC Symbol;Acc:HGNC:40022]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000244255	0.105	0	0.105	0.102	0.127	0	8.44	0	6.25	6.06	8.59	0	CFB	novel complement component 2 (C2) and complement factor B (CFB) protein	Human Diseases;Human Diseases;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system	ko05171//Coronavirus disease - COVID-19;ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01335;K01335;K01335	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	"GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0045087//innate immune response"	--
ENSG00000244274	41.446	39.329	39.808	40.104	34.445	49.952	969.26	923.97	687.48	692.85	682.04	852.8	DBNDD2	dysbindin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:15881]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0006469//negative regulation of protein kinase activity	--
ENSG00000244355	0	0	0	0	0	0	0	0	0	0	0	0	LY6G6D	lymphocyte antigen 6 family member G6D [Source:HGNC Symbol;Acc:HGNC:13935]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0030175//filopodium;GO:0031225//anchored component of membrane;GO:0032991//protein-containing complex;GO:0042995//cell projection;GO:0045202//synapse	GO:0005515//protein binding;GO:0030550//acetylcholine receptor inhibitor activity;GO:0042802//identical protein binding	GO:0095500//acetylcholine receptor signaling pathway;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000244362	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP19-7	keratin associated protein 19-7 [Source:HGNC Symbol;Acc:HGNC:18942]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000244395	0	0	0	0	0	0	0	0	0	0	0	0	RBMY1D	RNA binding motif protein Y-linked family 1 member D [Source:HGNC Symbol;Acc:HGNC:23915]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000244405	1.936	2.361	1.931	3.104	4.289	2.24	148	162	91	157	179	138	ETV5	ETS variant transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3494]	Human Diseases;Human Diseases	Cancer: overview;Cancer: specific types	ko05202//Transcriptional misregulation in cancer;ko05215//Prostate cancer	K15593;K15593	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0034599//cellular response to oxidative stress;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000244411	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP5-7	keratin associated protein 5-7 [Source:HGNC Symbol;Acc:HGNC:23602]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding	-	--
ENSG00000244414	0.225	0.224	0.102	0.102	0.332	0.204	6.06	6.05	2.03	2.03	7.06	4	CFHR1	complement factor H related 1 [Source:HGNC Symbol;Acc:HGNC:4888]	Organismal Systems	Immune system	ko04610//Complement and coagulation cascades	K23815	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0032991//protein-containing complex;GO:0072562//blood microparticle	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006956//complement activation;GO:0032091//negative regulation of protein binding;GO:0051838//cytolysis by host of symbiont cells	--
ENSG00000244437	0	0	0	0	0	0	0	0	0	0	0	0	IGKV3-15	immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000244462	33.268	28.483	28.916	28.372	29.101	27.094	2038.55	1861.2	1277	1305.65	1560.99	1334.24	RBM12	RNA binding motif protein 12 [Source:HGNC Symbol;Acc:HGNC:9898]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0043484//regulation of RNA splicing	--
ENSG00000244474	0	0	0	0	0	0.04	0	0	0	0	0	1.33	UGT1A4	UDP glucuronosyltransferase family 1 member A4 [Source:HGNC Symbol;Acc:HGNC:12536]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0006789//bilirubin conjugation;GO:0042167//heme catabolic process;GO:0045922//negative regulation of fatty acid metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation;GO:0070640//vitamin D3 metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:2001030//negative regulation of cellular glucuronidation	--
ENSG00000244476	10.138	9.5	8.612	23.864	23.715	28.035	671	632	421	1170	1326	1350	ERVFRD-1	"endogenous retrovirus group FRD member 1, envelope [Source:HGNC Symbol;Acc:HGNC:33823]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0000768//syncytium formation by plasma membrane fusion;GO:0006949//syncytium formation;GO:0007520//myoblast fusion	--
ENSG00000244482	0	0	0	0	0	0	0	0	0	0	0	0	LILRA6	leukocyte immunoglobulin like receptor A6 [Source:HGNC Symbol;Acc:HGNC:15495]	Organismal Systems;Organismal Systems	Immune system;Development and regeneration	ko04662//B cell receptor signaling pathway;ko04380//Osteoclast differentiation	K06512;K06512	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0032396//inhibitory MHC class I receptor activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000244486	14.758	15.664	16.503	17.721	18.676	15.935	1042	1114	863	931	1118	824	SCARF2	scavenger receptor class F member 2 [Source:HGNC Symbol;Acc:HGNC:19869]	-	-	-	-	GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005044//scavenger receptor activity;GO:0005515//protein binding	GO:0006897//endocytosis;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000244509	1.568	2.405	1.605	2.954	2.072	2.18	86	125	54	120	96	87	APOBEC3C	apolipoprotein B mRNA editing enzyme catalytic subunit 3C [Source:HGNC Symbol;Acc:HGNC:17353]	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0004126//cytidine deaminase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047844//deoxycytidine deaminase activity	GO:0002376//immune system process;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016554//cytidine to uridine editing;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0051607//defense response to virus;GO:0070383//DNA cytosine deamination;GO:0080111//DNA demethylation	--
ENSG00000244537	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP4-2	keratin associated protein 4-2 [Source:HGNC Symbol;Acc:HGNC:18900]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000244575	0	0	0	0	0.149	0	0	0	0	0	1	0	IGKV1-27	immunoglobulin kappa variable 1-27 [Source:HGNC Symbol;Acc:HGNC:5735]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000244588	0	0	0	0	0	0	0	0	0	0	0	0	RAD21L1	RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271]	-	-	-	-	GO:0000794//condensed nuclear chromosome;GO:0000795//synaptonemal complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005694//chromosome;GO:0008278//cohesin complex;GO:0030893//meiotic cohesin complex;GO:0034990//nuclear mitotic cohesin complex;GO:0034991//nuclear meiotic cohesin complex	GO:0003682//chromatin binding;GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006302//double-strand break repair;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion;GO:0007129//homologous chromosome pairing at meiosis;GO:0007130//synaptonemal complex assembly;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0051321//meiotic cell cycle;GO:0070197//meiotic attachment of telomere to nuclear envelope;GO:0072520//seminiferous tubule development;GO:1990414//replication-born double-strand break repair via sister chromatid exchange	--
ENSG00000244607	1.315	1.332	0.981	0.644	0.858	0.522	148.81	151.57	82	54	82	43	CCDC13	coiled-coil domain containing 13 [Source:HGNC Symbol;Acc:HGNC:26358]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0034451//centriolar satellite;GO:0042995//cell projection	GO:0005515//protein binding	GO:0006974//cellular response to DNA damage stimulus;GO:0030030//cell projection organization;GO:0031122//cytoplasmic microtubule organization;GO:1905515//non-motile cilium assembly	--
ENSG00000244617	0.437	0.746	0.212	0.759	0.518	0.344	14	24	5	18	14	8	ASPRV1	aspartic peptidase retroviral like 1 [Source:HGNC Symbol;Acc:HGNC:26321]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0016485//protein processing;GO:0043588//skin development	--
ENSG00000244623	0	0	0	0	0	0	0	0	0	0	0	0	OR2AE1	olfactory receptor family 2 subfamily AE member 1 [Source:HGNC Symbol;Acc:HGNC:15087]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000244624	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP20-1	keratin associated protein 20-1 [Source:HGNC Symbol;Acc:HGNC:18943]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament	-	-	--
ENSG00000244682	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000244687	51.355	52.2	49.879	54.463	55.521	52.77	2253.47	2294.14	1606.66	1768.6	2060	1685	UBE2V1	ubiquitin conjugating enzyme E2 V1 [Source:HGNC Symbol;Acc:HGNC:12494]	Human Diseases	Infectious disease: bacterial	ko05131//Shigellosis	K10704	GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031371//ubiquitin conjugating enzyme complex;GO:0032991//protein-containing complex;GO:0035370//UBC13-UEV1A complex;GO:0070062//extracellular exosome	GO:0005515//protein binding	"GO:0000209//protein polyubiquitination;GO:0006282//regulation of DNA repair;GO:0006301//postreplication repair;GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070534//protein K63-linked ubiquitination;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:1902533//positive regulation of intracellular signal transduction"	--
ENSG00000244694	1.099	0.964	1.153	1.486	1.423	1.292	230	167.33	124	182.75	219.26	159.41	PTCHD4	patched domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21345]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000244731	165.077	181.691	168.609	156.019	180.57	159.51	18582.17	20557.49	14017.77	13007.46	17172.65	13064.48	C4A	complement C4A (Rodgers blood group) [Source:HGNC Symbol;Acc:HGNC:1323]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03989;K03989;K03989;K03989;K03989;K03989	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0001849//complement component C1q complex binding;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding	"GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0045087//innate immune response;GO:2000427//positive regulation of apoptotic cell clearance"	--
ENSG00000244734	0	0	0	0	1.817	0	0	0	0	0	20	0	HBB	hemoglobin subunit beta [Source:HGNC Symbol;Acc:HGNC:4827]	Human Diseases;Human Diseases	Infectious disease: parasitic;Infectious disease: parasitic	ko05143//African trypanosomiasis;ko05144//Malaria	K13823;K13823	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0031838//haptoglobin-hemoglobin complex;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle;GO:1904724//tertiary granule lumen;GO:1904813//ficolin-1-rich granule lumen	GO:0004601//peroxidase activity;GO:0005344//oxygen carrier activity;GO:0005515//protein binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0030492//hemoglobin binding;GO:0031720//haptoglobin binding;GO:0031721//hemoglobin alpha binding;GO:0043177//organic acid binding;GO:0046872//metal ion binding	GO:0008217//regulation of blood pressure;GO:0010942//positive regulation of cell death;GO:0015670//carbon dioxide transport;GO:0015671//oxygen transport;GO:0030185//nitric oxide transport;GO:0042542//response to hydrogen peroxide;GO:0042744//hydrogen peroxide catabolic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0070293//renal absorption;GO:0070527//platelet aggregation;GO:0098869//cellular oxidant detoxification	--
ENSG00000244752	0.313	0.437	0.424	1.1	0.965	1.292	5	7	5	13	13	15	CRYBB2	crystallin beta B2 [Source:HGNC Symbol;Acc:HGNC:2398]	-	-	-	-	-	GO:0005198//structural molecule activity;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0002088//lens development in camera-type eye;GO:0007601//visual perception;GO:0043010//camera-type eye development;GO:0050896//response to stimulus	--
ENSG00000244754	15.255	14.915	14.042	12.053	13.893	16.386	740	711	493	444	599	582	N4BP2L2	NEDD4 binding protein 2 like 2 [Source:HGNC Symbol;Acc:HGNC:26916]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017053//transcription repressor complex;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0019899//enzyme binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:1902037//negative regulation of hematopoietic stem cell differentiation	--
ENSG00000245680	3.626	3.32	3.863	3.186	2.11	3.698	326.57	248.62	203.87	185.67	169.24	210.8	ZNF585B	zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000245848	0.482	0.406	0.301	0.3	0.57	0.255	26	22	12	12	26	10	CEBPA	CCAAT enhancer binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1833]	Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types	ko05200//Pathways in cancer;ko05202//Transcriptional misregulation in cancer;ko04932//Non-alcoholic fatty liver disease;ko05221//Acute myeloid leukemia	K09055;K09055;K09055;K09055	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0036488//CHOP-C/EBP complex;GO:0043231//intracellular membrane-bounded organelle;GO:0090575//RNA polymerase II transcription regulator complex;GO:1990647//C/EBP complex	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0097677//STAT family protein binding;GO:0140297//DNA-binding transcription factor binding"	"GO:0000050//urea cycle;GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001889//liver development;GO:0001892//embryonic placenta development;GO:0006091//generation of precursor metabolites and energy;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007005//mitochondrion organization;GO:0007219//Notch signaling pathway;GO:0008203//cholesterol metabolic process;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0019221//cytokine-mediated signaling pathway;GO:0030099//myeloid cell differentiation;GO:0030225//macrophage differentiation;GO:0030324//lung development;GO:0030851//granulocyte differentiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042127//regulation of cell population proliferation;GO:0042593//glucose homeostasis;GO:0043032//positive regulation of macrophage activation;GO:0045444//fat cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0045945//positive regulation of transcription by RNA polymerase III;GO:0048469//cell maturation;GO:0048839//inner ear development;GO:0050729//positive regulation of inflammatory response;GO:0050872//white fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0055088//lipid homeostasis;GO:0070102//interleukin-6-mediated signaling pathway;GO:0071285//cellular response to lithium ion;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0140467//integrated stress response signaling"	TF_bZIP
ENSG00000246705	16.296	19.225	22.244	24.992	20.063	16.973	222	261	229	255	232	168	H2AJ	H2A.J histone [Source:HGNC Symbol;Acc:HGNC:14456]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000246922	19.618	18.788	17.82	17.387	18.019	14.634	689	660	466	456	539	377	UBAP1L	ubiquitin associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:40028]	-	-	-	-	GO:0000813//ESCRT I complex	GO:0043130//ubiquitin binding	GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	--
ENSG00000247077	9.002	10.06	11.055	9.476	10.912	11.774	348	394	381	342	362	330	PGAM5	"PGAM family member 5, mitochondrial serine/threonine protein phosphatase [Source:HGNC Symbol;Acc:HGNC:28763]"	Cellular Processes;Environmental Information Processing;Cellular Processes	Cell growth and death;Signal transduction;Transport and catabolism	ko04217//Necroptosis;ko04668//TNF signaling pathway;ko04137//Mitophagy - animal	K15637;K15637;K15637	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004722//protein serine/threonine phosphatase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0044877//protein-containing complex binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0012501//programmed cell death;GO:0016236//macroautophagy;GO:0035970//peptidyl-threonine dephosphorylation;GO:0050790//regulation of catalytic activity;GO:0070266//necroptotic process;GO:0090141//positive regulation of mitochondrial fission;GO:0120163//negative regulation of cold-induced thermogenesis	--
ENSG00000247315	18.71	19.346	20.209	22.042	20.093	18.564	1068	1110	852	932	969	771	ZCCHC3	zinc finger CCHC-type containing 3 [Source:HGNC Symbol;Acc:HGNC:16230]	-	-	-	-	GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0002218//activation of innate immune response;GO:0002376//immune system process;GO:0009597//detection of virus;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:1900246//positive regulation of RIG-I signaling pathway	--
ENSG00000247595	0	0	0	0	0	0.231	0	0	0	0	0	2	SPTY2D1OS	SPTY2D1 opposite strand [Source:HGNC Symbol;Acc:HGNC:44122]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000247596	11.458	11.475	12.391	13.724	12.462	12.249	385	383	306	341	348	300	TWF2	twinfilin actin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9621]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005884//actin filament;GO:0030016//myofibril;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030426//growth cone;GO:0032420//stereocilium;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	"GO:0003723//RNA binding;GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0045296//cadherin binding;GO:0051015//actin filament binding"	GO:0010591//regulation of lamellipodium assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0010976//positive regulation of neuron projection development;GO:0030030//cell projection organization;GO:0030042//actin filament depolymerization;GO:0030837//negative regulation of actin filament polymerization;GO:0032532//regulation of microvillus length;GO:0032956//regulation of actin cytoskeleton organization;GO:0042989//sequestering of actin monomers;GO:0045773//positive regulation of axon extension;GO:0051016//barbed-end actin filament capping;GO:0071300//cellular response to retinoic acid;GO:0071363//cellular response to growth factor stimulus	--
ENSG00000247626	2.118	2.234	2.523	2.602	2.111	2.955	133	141	117	121	112	135	MARS2	"methionyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25133]"	Metabolism;Genetic Information Processing;Metabolism	Global and overview maps;Translation;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis;ko00450//Selenocompound metabolism	K01874;K01874;K01874	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004825//methionine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006412//translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006431//methionyl-tRNA aminoacylation	--
ENSG00000247746	5.096	4.028	5.093	4.976	4.904	4.512	426	367	285	277	343	305	USP51	ubiquitin specific peptidase 51 [Source:HGNC Symbol;Acc:HGNC:23086]	-	-	-	-	GO:0005694//chromosome	GO:0003682//chromatin binding;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0042393//histone binding;GO:0046872//metal ion binding	GO:0006281//DNA repair;GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0010564//regulation of cell cycle process;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0016578//histone deubiquitination;GO:0016579//protein deubiquitination;GO:2001020//regulation of response to DNA damage stimulus;GO:2001032//regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000248098	31.272	32.903	34.388	38.8	36.435	33.96	1129.93	1178	912.2	1038.47	1112.25	892.82	BCKDHA	branched chain keto acid dehydrogenase E1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:986]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism"	K00166;K00166;K00166	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex	"GO:0003863//3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0016831//carboxy-lyase activity;GO:0046872//metal ion binding"	GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000248099	0	0.192	0	0	0.228	0	0	3	0	0	3	0	INSL3	insulin like 3 [Source:HGNC Symbol;Acc:HGNC:6086]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04926//Relaxin signaling pathway	K21999;K21999	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm	GO:0001664//G protein-coupled receptor binding;GO:0002020//protease binding;GO:0005102//signaling receptor binding;GO:0005158//insulin receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding	GO:0001556//oocyte maturation;GO:0007193//adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0008584//male gonad development;GO:0010634//positive regulation of epithelial cell migration;GO:0043066//negative regulation of apoptotic process;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0090303//positive regulation of wound healing	--
ENSG00000248109	0	0	0	0	0	0	0	0	0	0	0	0	MARCOL	MARCO like [Source:HGNC Symbol;Acc:HGNC:53644]	-	-	-	-	GO:0005615//extracellular space;GO:0031012//extracellular matrix	GO:0005201//extracellular matrix structural constituent	GO:0030198//extracellular matrix organization	--
ENSG00000248144	0.083	0	0	0	0.13	0	1	0	0	0	2	0	ADH1C	"alcohol dehydrogenase 1C (class I), gamma polypeptide [Source:HGNC Symbol;Acc:HGNC:251]"	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00980//Metabolism of xenobiotics by cytochrome P450;ko00010//Glycolysis / Gluconeogenesis;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00350//Tyrosine metabolism	K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951;K13951	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	"GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004745//NAD-retinol dehydrogenase activity;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0046872//metal ion binding"	GO:0006069//ethanol oxidation;GO:0042572//retinol metabolic process;GO:0042573//retinoic acid metabolic process	--
ENSG00000248167	0	0	0	0	0	0	0	0	0	0	0	0	TRIM39-RPP21	TRIM39-RPP21 readthrough [Source:HGNC Symbol;Acc:HGNC:38845]	-	-	-	-	GO:0005829//cytosol;GO:1902494//catalytic complex;GO:1990904//ribonucleoprotein complex	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0006396//RNA processing;GO:0034470//ncRNA processing	--
ENSG00000248235	0	0	0.339	0.061	0	0.373	0	0	5.08	0.92	0	2.99	C8orf58	novel protein	-	-	-	-	-	-	-	--
ENSG00000248329	0	0	0	0	0	0	0	0	0	0	0	0	APELA	apelin receptor early endogenous ligand [Source:HGNC Symbol;Acc:HGNC:48925]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04371//Apelin signaling pathway	K25355;K25355	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005179//hormone activity;GO:0031704//apelin receptor binding	GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0007507//heart development;GO:0007509//mesoderm migration involved in gastrulation;GO:0007512//adult heart development;GO:0030154//cell differentiation;GO:0035050//embryonic heart tube development;GO:0045766//positive regulation of angiogenesis;GO:0045823//positive regulation of heart contraction;GO:0060183//apelin receptor signaling pathway;GO:0060674//placenta blood vessel development;GO:0060976//coronary vasculature development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090133//mesendoderm migration;GO:0090134//cell migration involved in mesendoderm migration;GO:1901165//positive regulation of trophoblast cell migration;GO:1903589//positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:1904022//positive regulation of G protein-coupled receptor internalization	--
ENSG00000248333	13.163	13.543	14.504	10.95	12.912	11.694	731.04	798.04	616.07	461.75	623.21	498.89	CDK11B	cyclin dependent kinase 11B [Source:HGNC Symbol;Acc:HGNC:1729]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	"GO:0000278//mitotic cell cycle;GO:0001558//regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0016310//phosphorylation;GO:0043484//regulation of RNA splicing;GO:0050684//regulation of mRNA processing"	--
ENSG00000248383	0.355	0.282	0.219	0.348	0.336	0.533	30	25.45	17.86	27.94	24	41.67	PCDHAC1	"protocadherin alpha subfamily C, 1 [Source:HGNC Symbol;Acc:HGNC:8676]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000248385	0	0	0	0	0	0	0	0	0	0	0	0	TARM1	"T cell-interacting, activating receptor on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:37250]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0045087//innate immune response;GO:2000515//negative regulation of CD4-positive, alpha-beta T cell activation"	--
ENSG00000248405	0.516	0	0	1.412	0.605	0.519	21.53	0	0	43.68	21.42	15.84	PRR5-ARHGAP8	PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:HGNC:34512]	-	-	-	-	-	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000248483	0.017	0	0	0.008	0	0	3	0	0	1	0	0	POU5F2	"POU domain class 5, transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:26367]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Pou
ENSG00000248485	0.069	0.205	0	0.046	0	0.094	2	6	0	1	0	2	PCP4L1	Purkinje cell protein 4 like 1 [Source:HGNC Symbol;Acc:HGNC:20448]	-	-	-	-	-	-	-	--
ENSG00000248487	57.874	57.735	63.717	85.196	77.283	73.728	1276.54	1283.14	1035.65	1386.48	1441.48	1186.13	ABHD14A	abhydrolase domain containing 14A [Source:HGNC Symbol;Acc:HGNC:24538]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016787//hydrolase activity	-	--
ENSG00000248592	1.226	0.932	2.556	2.047	1.44	1.603	35.73	26.14	55.01	44.18	35.46	33.98	STIMATE-MUSTN1	STIMATE-MUSTN1 readthrough [Source:HGNC Symbol;Acc:HGNC:38834]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0002062//chondrocyte differentiation;GO:0035988//chondrocyte proliferation;GO:0042246//tissue regeneration	--
ENSG00000248643	0.715	2.763	1.878	1.819	2.371	2.333	26.05	75.61	49.56	39.07	67.72	62.04	RBM14-RBM4	RBM14-RBM4 readthrough [Source:HGNC Symbol;Acc:HGNC:38840]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding	-	--
ENSG00000248672	0.01	0.01	0	0.026	0.046	0.007	1.11	1.14	0	2.19	4.4	0.62	LY75-CD302	LY75-CD302 readthrough [Source:HGNC Symbol;Acc:HGNC:38828]	-	-	-	-	-	-	-	--
ENSG00000248710	0.444	0	0.228	0.185	0.193	0.077	30.95	0	11.74	9.56	11.39	3.92	IFT80	TRIM59 and iFT80 readthrough	-	-	-	-	-	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000248712	0.357	0.327	0.788	0.43	0.579	0.491	6	5	12	6	8	6	CCDC153	coiled-coil domain containing 153 [Source:HGNC Symbol;Acc:HGNC:27446]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000248713	0.009	0.005	0.006	0	0.016	0	2	1	1	0	3	0	C4orf54	chromosome 4 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:27741]	-	-	-	-	-	-	-	--
ENSG00000248746	0	0	0	0.045	0	0	0	0	0	2	0	0	ACTN3	actinin alpha 3 [Source:HGNC Symbol;Acc:HGNC:165]	Human Diseases	Cardiovascular disease	ko05412//Arrhythmogenic right ventricular cardiomyopathy	K21073	GO:0005829//cytosol;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005903//brush border;GO:0005925//focal adhesion;GO:0030017//sarcomere;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031143//pseudopodium;GO:0042995//cell projection;GO:0070062//extracellular exosome;GO:0110165//cellular anatomical entity	GO:0003779//actin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0042802//identical protein binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0014728//regulation of the force of skeletal muscle contraction;GO:0014732//skeletal muscle atrophy;GO:0014883//transition between fast and slow fiber;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0030036//actin cytoskeleton organization;GO:0031448//positive regulation of fast-twitch skeletal muscle fiber contraction;GO:0042981//regulation of apoptotic process;GO:0045820//negative regulation of glycolytic process;GO:0048041//focal adhesion assembly;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0055001//muscle cell development;GO:0060349//bone morphogenesis;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0090257//regulation of muscle system process;GO:0090324//negative regulation of oxidative phosphorylation;GO:0120163//negative regulation of cold-induced thermogenesis;GO:1900159//positive regulation of bone mineralization involved in bone maturation;GO:1901078//negative regulation of relaxation of muscle;GO:1903715//regulation of aerobic respiration;GO:1904025//positive regulation of glucose catabolic process to lactate via pyruvate	--
ENSG00000248751	0.3	0.499	0.524	1.077	0.887	0.47	11.99	20.52	15.57	32.67	30.15	13.54	TBC1D10A	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0034618//arginine binding	GO:0090630//activation of GTPase activity;GO:1902531//regulation of intracellular signal transduction;GO:1903432//regulation of TORC1 signaling;GO:1903577//cellular response to L-arginine;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000248767	0	0	0	0	0	0	0	0	0	0	0	0	FOXL3	forkhead box L3 [Source:HGNC Symbol;Acc:HGNC:54201]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000248771	0	0	0	0	0	0	0	0	0	0	0	0	SMIM31	small integral membrane protein 31 [Source:HGNC Symbol;Acc:HGNC:49638]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon	-	-	--
ENSG00000248871	0	0	0	0	0	0	0	0	0	0	0	0	TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough [Source:HGNC Symbol;Acc:HGNC:33537]	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Immune disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05323//Rheumatoid arthritis;ko04672//Intestinal immune network for IgA production	K05475;K05475;K05475	GO:0005615//extracellular space;GO:0016020//membrane	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding	GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway	--
ENSG00000248905	0.71	0.696	0.397	0.608	1.752	1.444	154	126	72	115	162.02	100	FMN1	formin 1 [Source:HGNC Symbol;Acc:HGNC:3768]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0016020//membrane;GO:0030054//cell junction	GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0017124//SH3 domain binding	GO:0010467//gene expression;GO:0030838//positive regulation of actin filament polymerization;GO:0035136//forelimb morphogenesis;GO:0035137//hindlimb morphogenesis;GO:0045010//actin nucleation;GO:0048705//skeletal system morphogenesis;GO:0051127//positive regulation of actin nucleation;GO:0051894//positive regulation of focal adhesion assembly;GO:0060173//limb development;GO:0072092//ureteric bud invasion	--
ENSG00000248919	2.691	3.798	3.802	3.515	3.839	4.521	139.03	197.26	145.09	134.51	167.58	169.98	ATP5MF-PTCD1	ATP5MF-PTCD1 readthrough [Source:HGNC Symbol;Acc:HGNC:38844]	-	-	-	-	"GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0005515//protein binding	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport	--
ENSG00000248920	0	0	0	0	0	0	0	0	0	0	0	0	USP17L19	ubiquitin specific peptidase 17 like family member 19 [Source:HGNC Symbol;Acc:HGNC:44447]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000248933	0	0	0	0	0	0	0	0	0	0	0	0	USP17L22	ubiquitin specific peptidase 17 like family member 22 [Source:HGNC Symbol;Acc:HGNC:44450]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000248993	0	0	0	0	0	0	0	0	0	0	0	0	HLA-DMB	novel  protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Infectious disease: viral;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: viral;Transport and catabolism;Immune disease;Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune disease;Signaling molecules and interaction;Infectious disease: parasitic;Cardiovascular disease;Immune disease;Immune system;Immune system;Infectious disease: parasitic;Immune disease;Immune disease;Immune system;Immune system;Immune disease;Endocrine and metabolic disease;Immune disease	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05152//Tuberculosis;ko05166//Human T-cell leukemia virus 1 infection;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05164//Influenza A;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05140//Leishmaniasis;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko05330//Allograft rejection;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752;K06752	GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0042613//MHC class II protein complex	GO:0023026//MHC class II protein complex binding	GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050870//positive regulation of T cell activation	--
ENSG00000249104	0	0	0	0	0.004	0	0	0	0	0	0.11	0	USP17L17	ubiquitin specific peptidase 17 like family member 17 [Source:HGNC Symbol;Acc:HGNC:44445]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000249115	2.432	2.809	2.505	2.65	2.524	3.393	190	219	147	150	164	186	HAUS5	HAUS augmin like complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:29130]	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:1990498//mitotic spindle microtubule	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division	--
ENSG00000249139	0	0	0	0	0	0	0	0	0	0	0	0	EPPIN-WFDC6	EPPIN-WFDC6 readthrough [Source:HGNC Symbol;Acc:HGNC:38825]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0032991//protein-containing complex;GO:0097524//sperm plasma membrane	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity;GO:0042742//defense response to bacterium;GO:0043086//negative regulation of catalytic activity;GO:0052547//regulation of peptidase activity;GO:0090281//negative regulation of calcium ion import;GO:1901318//negative regulation of flagellated sperm motility	--
ENSG00000249141	0	0	0	0	0	0	0	0	0	0	0	0	RNASET2	novel protein	-	-	-	-	GO:0005576//extracellular region;GO:0043202//lysosomal lumen	GO:0003723//RNA binding;GO:0004521//endoribonuclease activity;GO:0033897//ribonuclease T2 activity	"GO:0006401//RNA catabolic process;GO:0016070//RNA metabolic process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000249156	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L12	TATA-box binding protein associated factor 11 like 12 [Source:HGNC Symbol;Acc:HGNC:53855]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000249158	8.564	7.842	8.198	8.304	6.811	7.403	818.19	774.63	561.48	588.38	637.79	534.67	PCDHA11	protocadherin alpha 11 [Source:HGNC Symbol;Acc:HGNC:8665]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000249209	0	0	0	0.626	0.217	0.441	0	0	0	10.36	4.1	7.18	ATP5PO	novel protein similar to ATP synthase delta (OSCP) subunit domain	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko00190//Oxidative phosphorylation	K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137;K02137	"GO:0000274//mitochondrial proton-transporting ATP synthase, stator stalk;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)"	"GO:0046933//proton-transporting ATP synthase activity, rotational mechanism"	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport	--
ENSG00000249222	0	0	0	0	0	0	0	0	0	0	0	0	ATP5MGL	ATP synthase membrane subunit g like [Source:HGNC Symbol;Acc:HGNC:13213]	Metabolism;Organismal Systems;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation	K02140;K02140;K02140	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)"	GO:0015078//proton transmembrane transporter activity	GO:0006754//ATP biosynthetic process;GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport	--
ENSG00000249240	0.303	0.501	0	0	0	1.702	4.72	7.84	0	0	0	19.26	PLEKHO2	novel protein	-	-	-	-	-	GO:0005515//protein binding	GO:0071888//macrophage apoptotic process	--
ENSG00000249242	0.91	1.207	0.965	0.901	0.682	0.688	60	80	47	44	38	33	TMEM150C	transmembrane protein 150C [Source:HGNC Symbol;Acc:HGNC:37263]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0008381//mechanosensitive ion channel activity	GO:0019230//proprioception;GO:0034220//ion transmembrane transport;GO:0071260//cellular response to mechanical stimulus	--
ENSG00000249319	0.256	0	0.432	0.114	0.168	0.247	4.9	0	6.1	1.62	2.72	3.44	ASL	novel protein	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00250//Alanine, aspartate and glutamate metabolism;ko00220//Arginine biosynthesis"	K01755;K01755;K01755;K01755	GO:0005634//nucleus;GO:0005829//cytosol;GO:0030880//RNA polymerase complex;GO:0043231//intracellular membrane-bounded organelle	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004056//argininosuccinate lyase activity	"GO:0000050//urea cycle;GO:0006352//DNA-templated transcription, initiation;GO:0006526//arginine biosynthetic process;GO:0042450//arginine biosynthetic process via ornithine;GO:0044237//cellular metabolic process"	--
ENSG00000249437	1.163	0.907	0.858	1.045	0.991	1.012	118	71	80	84	90	76	NAIP	NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634]	Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko05134//Legionellosis	K12807;K12807;K12807;K12807;K12807	GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0061702//inflammasome complex;GO:0072557//IPAF inflammasome complex	GO:0000166//nucleotide binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030414//peptidase inhibitor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872//metal ion binding;GO:0120283//protein serine/threonine kinase binding	GO:0002221//pattern recognition receptor signaling pathway;GO:0002376//immune system process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0007399//nervous system development;GO:0010466//negative regulation of peptidase activity;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0016045//detection of bacterium;GO:0032268//regulation of cellular protein metabolic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042742//defense response to bacterium;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0046456//icosanoid biosynthetic process;GO:0050729//positive regulation of inflammatory response;GO:0052548//regulation of endopeptidase activity;GO:0070269//pyroptosis	--
ENSG00000249467	0	0	0	0	0	0	0	0	0	0	0	0	H2AL1Q	H2A.L variant histone 1Q [Source:HGNC Symbol;Acc:HGNC:53959]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000249471	2.012	2.669	2.034	1.452	1.905	1.687	112.43	126.48	81.13	63.58	87.91	65	ZNF324B	zinc finger protein 324B [Source:HGNC Symbol;Acc:HGNC:33107]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000249481	0.044	0.068	0	0	0.052	0.016	1	1.56	0	0	1	1	SPATS1	spermatogenesis associated serine rich 1 [Source:HGNC Symbol;Acc:HGNC:22957]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000249581	0	0	0	0	0	0	0	0	0	0	0	0	CLRN2	clarin 2 [Source:HGNC Symbol;Acc:HGNC:33939]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032421//stereocilium bundle	GO:0005515//protein binding	GO:0007605//sensory perception of sound;GO:0042491//inner ear auditory receptor cell differentiation;GO:0060088//auditory receptor cell stereocilium organization;GO:0120045//stereocilium maintenance	--
ENSG00000249590	0	0	0.112	0	0	0.22	0	0	1.5	0	0	2.89	SEC14L2	novel SEC14-like 2 (S. cerevisiae) (SEC14L2) and mitochondrial protein 18 kDa (MTP18) protein	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	-	-	--
ENSG00000249624	0.234	0.393	0	0.876	0.297	0.212	8.73	15.09	0	36.52	19.59	12.59	IFNAR2	novel protein	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Signaling molecules and interaction;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Infectious disease: viral;Development and regeneration;Immune system	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04060//Cytokine-cytokine receptor interaction;ko05169//Epstein-Barr virus infection;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04650//Natural killer cell mediated cytotoxicity;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko04630//JAK-STAT signaling pathway;ko04217//Necroptosis;ko05160//Hepatitis C;ko05162//Measles;ko04380//Osteoclast differentiation;ko04620//Toll-like receptor signaling pathway	K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131;K05131	GO:0005887//integral component of plasma membrane	GO:0004896//cytokine receptor activity;GO:0004905//type I interferon receptor activity;GO:0005515//protein binding	GO:0019221//cytokine-mediated signaling pathway;GO:0060337//type I interferon signaling pathway	--
ENSG00000249662	0	0	0	0	0	0	0	0	0	0	0	0	LINC02218	long intergenic non-protein coding RNA 2218 [Source:HGNC Symbol;Acc:HGNC:53085]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000249693	0.058	0.058	0.158	0.118	0.138	0.16	2	2	4	3	4	4	THEGL	theg spermatid protein like [Source:HGNC Symbol;Acc:HGNC:43771]	-	-	-	-	-	-	-	--
ENSG00000249709	3.755	3.458	3.303	2.662	3.344	3.91	203	208	146	118	147	148	ZNF564	zinc finger protein 564 [Source:HGNC Symbol;Acc:HGNC:31106]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000249715	0.067	0.067	0.041	0.02	0.018	0.01	9	9	4	2	2	1	FER1L5	fer-1 like family member 5 [Source:HGNC Symbol;Acc:HGNC:19044]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0031410//cytoplasmic vesicle	GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0001778//plasma membrane repair;GO:0002280//monocyte activation involved in immune response;GO:0002281//macrophage activation involved in immune response;GO:0006906//vesicle fusion;GO:0007009//plasma membrane organization;GO:0007520//myoblast fusion;GO:0033292//T-tubule organization;GO:0050765//negative regulation of phagocytosis;GO:0061025//membrane fusion	--
ENSG00000249730	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000249751	0	0	0	0	0.055	0	0	0	0	0	1	0	ECSCR	endothelial cell surface expressed chemotaxis and apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:35454]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0016525//negative regulation of angiogenesis;GO:0030154//cell differentiation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:2000353//positive regulation of endothelial cell apoptotic process	--
ENSG00000249773	0.208	1.284	0.204	0.284	0.474	0.052	7.49	46.38	5.4	7.55	14.4	1.35	MRPS17	novel zinc finger protein 713 (ZNF713) and mitochondrial ribosomal protein S17 (MRPS17) protein	Genetic Information Processing	Translation	ko03010//Ribosome	K02961	GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	"GO:0006355//regulation of transcription, DNA-templated;GO:0006412//translation"	--
ENSG00000249811	0	0	0	0	0	0	0	0	0	0	0	0	USP17L21	ubiquitin specific peptidase 17 like family member 21 [Source:HGNC Symbol;Acc:HGNC:44449]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000249853	0	0	0	0	0.029	0	0	0	0	0	2	0	HS3ST5	heparan sulfate-glucosamine 3-sulfotransferase 5 [Source:HGNC Symbol;Acc:HGNC:19419]	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K08104	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0016740//transferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding	"GO:0006024//glycosaminoglycan biosynthetic process;GO:0006477//protein sulfation;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:0046596//regulation of viral entry into host cell;GO:0050819//negative regulation of coagulation"	--
ENSG00000249860	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L5	MT-RNR2 like 5 [Source:HGNC Symbol;Acc:HGNC:37162]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003674//molecular_function;GO:0048019//receptor antagonist activity	GO:0072734//cellular response to staurosporine;GO:1900118//negative regulation of execution phase of apoptosis;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000249861	0	0	0	0	0	0	0	0	0	0	0	0	LGALS16	galectin 16 [Source:HGNC Symbol;Acc:HGNC:40039]	-	-	-	-	GO:0005575//cellular_component;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0030246//carbohydrate binding;GO:0030395//lactose binding	GO:0006915//apoptotic process;GO:0070234//positive regulation of T cell apoptotic process	--
ENSG00000249884	0	0.16	0	0	0.094	0.218	0	3.79	0	0	1.32	3.74	RNF103-CHMP3	RNF103-CHMP3 readthrough [Source:HGNC Symbol;Acc:HGNC:38847]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12193;K12193	GO:0005783//endoplasmic reticulum	GO:0004842//ubiquitin-protein transferase activity	GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0016032//viral process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0061952//midbody abscission;GO:0140014//mitotic nuclear division	--
ENSG00000249915	23.008	24.526	20.892	20.982	20.577	26.358	526.89	563.33	352.26	356.92	393.58	436.97	PDCD6	programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0031410//cytoplasmic vesicle;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0070062//extracellular exosome;GO:0070971//endoplasmic reticulum exit site	GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043495//protein-membrane adaptor activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0048306//calcium-dependent protein binding;GO:1990756//ubiquitin ligase-substrate adaptor activity	GO:0001525//angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010595//positive regulation of endothelial cell migration;GO:0014029//neural crest formation;GO:0014032//neural crest cell development;GO:0016567//protein ubiquitination;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0032007//negative regulation of TOR signaling;GO:0034605//cellular response to heat;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0048208//COPII vesicle coating;GO:0051592//response to calcium ion;GO:0051898//negative regulation of protein kinase B signaling;GO:0097190//apoptotic signaling pathway;GO:1902527//positive regulation of protein monoubiquitination	--
ENSG00000249931	0.069	0.072	0.07	0.097	0.081	0	7.38	7.76	5.54	7.7	7.33	0	GOLGA8K	golgin A8 family member K [Source:HGNC Symbol;Acc:HGNC:38652]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000249948	0	0.024	0	0	0	0	0	1	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000249961	0	0	0	0	0	0	0	0	0	0	0	0	TERB1	telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005637//nuclear inner membrane;GO:0005694//chromosome;GO:0016020//membrane;GO:0070187//shelterin complex"	GO:0005515//protein binding	GO:0007129//homologous chromosome pairing at meiosis;GO:0045141//meiotic telomere clustering;GO:0051321//meiotic cell cycle;GO:0070197//meiotic attachment of telomere to nuclear envelope	MYB
ENSG00000249967	1.34	0.3	1.742	0.695	0	1.674	51.36	11.57	49.32	19.74	0	46.69	PI4K2A	novel protein	Metabolism;Environmental Information Processing;Metabolism	Global and overview maps;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K13711;K13711;K13711	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0016310//phosphorylation;GO:0044238//primary metabolic process;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000249992	14.448	15.479	17.448	10.752	10.617	8.91	546	588	487	301	339	245	TMEM158	transmembrane protein 158 [Source:HGNC Symbol;Acc:HGNC:30293]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0042277//peptide binding	-	--
ENSG00000250021	11.181	10.713	10.985	10.548	9.898	8.403	565.66	544.77	410.43	395.28	423.07	309.31	ARPIN-AP3S2	ARPIN-AP3S2 readthrough [Source:HGNC Symbol;Acc:HGNC:38824]	-	-	-	-	GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030117//membrane coat;GO:0030123//AP-3 adaptor complex;GO:0030659//cytoplasmic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle	-	GO:0006886//intracellular protein transport;GO:0006896//Golgi to vacuole transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0051126//negative regulation of actin nucleation	--
ENSG00000250036	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-37	immunoglobulin kappa variable 1D-37 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5755]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000250067	0.791	0.857	0.844	0.771	0.662	0.595	41.86	49.76	36	33	32.33	25	YJEFN3	YjeF N-terminal domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24785]	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding;GO:0052856//NADHX epimerase activity	GO:0002040//sprouting angiogenesis;GO:0006869//lipid transport;GO:0008593//regulation of Notch signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0016525//negative regulation of angiogenesis;GO:0031580//membrane raft distribution;GO:0071425//hematopoietic stem cell proliferation	--
ENSG00000250120	0.337	0.195	0.448	0.294	0.345	0.192	46.45	30.9	45.57	30.57	32.5	18.8	PCDHA10	protocadherin alpha 10 [Source:HGNC Symbol;Acc:HGNC:8664]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000250151	0.805	1.924	2.901	2.613	1.755	0.666	31.31	63.53	48.57	41.32	42.44	15.58	ARPC4-TTLL3	ARPC4-TTLL3 readthrough [Source:HGNC Symbol;Acc:HGNC:38830]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0015629//actin cytoskeleton;GO:0042995//cell projection	GO:0003779//actin binding;GO:0070735//protein-glycine ligase activity	GO:0006464//cellular protein modification process;GO:0018094//protein polyglycylation;GO:0030041//actin filament polymerization;GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation	--
ENSG00000250254	0.066	0.131	0	0	0	0	1	2	0	0	0	0	PTTG2	pituitary tumor-transforming 2 [Source:HGNC Symbol;Acc:HGNC:9691]	Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: viral;Cell growth and death;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04114//Oocyte meiosis;ko04110//Cell cycle	K06635;K06635;K06635	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0017124//SH3 domain binding	GO:0045143//homologous chromosome segregation;GO:0051276//chromosome organization;GO:2000816//negative regulation of mitotic sister chromatid separation	--
ENSG00000250264	1.381	1.279	0.873	1.341	0.763	0.889	77.49	72.14	36.19	55.75	36.15	36.3	TAP2	"novel protein, TAP2-HLA-DOB readthrough"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Transport and catabolism;Infectious disease: viral;Immune disease;Immune system;Membrane transport	ko05168//Herpes simplex virus 1 infection;ko05169//Epstein-Barr virus infection;ko05163//Human cytomegalovirus infection;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05340//Primary immunodeficiency;ko04612//Antigen processing and presentation;ko02010//ABC transporters	K05654;K05654;K05654;K05654;K05654;K05654;K05654;K05654	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016607//nuclear speck;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042613//MHC class II protein complex;GO:0042824//MHC class I peptide loading complex;GO:0042825//TAP complex	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0015433//ABC-type peptide antigen transporter activity;GO:0015440//ABC-type peptide transporter activity;GO:0042287//MHC protein binding;GO:0042288//MHC class I protein binding;GO:0042626//ATPase-coupled transmembrane transporter activity;GO:0046978//TAP1 binding;GO:0140359//ABC-type transporter activity;GO:1904680//peptide transmembrane transporter activity	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0015833//peptide transport;GO:0019882//antigen processing and presentation;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0055085//transmembrane transport	--
ENSG00000250298	0	0	0	0.043	0	0	0	0	0	1	0	0	GIMD1	GIMAP family P-loop NTPase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:44141]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005525//GTP binding	-	--
ENSG00000250305	0.307	0.296	0.159	0.962	0.504	0.437	38	32	19	37	38	22	TRMT9B	tRNA methyltransferase 9B (putative) [Source:HGNC Symbol;Acc:HGNC:26725]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0000049//tRNA binding;GO:0008168//methyltransferase activity;GO:0008175//tRNA methyltransferase activity;GO:0016300//tRNA (uracil) methyltransferase activity;GO:0016740//transferase activity	GO:0002098//tRNA wobble uridine modification;GO:0006400//tRNA modification;GO:0008033//tRNA processing;GO:0030488//tRNA methylation;GO:0032259//methylation	--
ENSG00000250312	0.644	0.769	0.447	0.698	0.602	0.756	39	47	19	29	28	30.06	ZNF718	zinc finger protein 718 [Source:HGNC Symbol;Acc:HGNC:26889]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000250317	17.469	17.902	18.894	18.556	15.027	16.655	333	343	266	262	242	231	SMIM20	small integral membrane protein 20 [Source:HGNC Symbol;Acc:HGNC:37260]	-	-	-	-	GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000250349	0	0.077	0	0.361	0	0	0	1.54	0	5.29	0	0	TSPAN7	novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K06571	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	-	--
ENSG00000250361	0	0	0	0	0	0	0	0	0	0	0	0	GYPB	glycophorin B (MNS blood group) [Source:HGNC Symbol;Acc:HGNC:4703]	Human Diseases	Infectious disease: parasitic	ko05144//Malaria	K20925	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000250366	0.09	0.09	0.338	0.311	0.464	0.373	6	6	16	14	26	18	TUNAR	TCL1 upstream neural differentiation-associated RNA [Source:HGNC Symbol;Acc:HGNC:44088]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000250374	0	0	0	0	0.031	0	0	0	0	0	1	0	TRIM75P	"tripartite motif containing 75, pseudogene [Source:HGNC Symbol;Acc:HGNC:32686]"	-	-	-	-	GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0007144//female meiosis I;GO:0010468//regulation of gene expression;GO:0016567//protein ubiquitination;GO:0045087//innate immune response	--
ENSG00000250423	0	0	0	0	0	0	0	0	0	0	0	0	KIAA1210	KIAA1210 [Source:HGNC Symbol;Acc:HGNC:29218]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0031410//cytoplasmic vesicle;GO:0061832//basal ectoplasmic specialization	-	-	--
ENSG00000250424	0	0	0	0	0	0	0	0	0	0	0	0	AQP1	"novel protein, MINDY4 and AQP1 readthrough"	Organismal Systems;Organismal Systems;Organismal Systems	Digestive system;Endocrine system;Excretory system	ko04976//Bile secretion;ko04924//Renin secretion;ko04964//Proximal tubule bicarbonate reclamation	K09864;K09864;K09864	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008519//ammonium transmembrane transporter activity;GO:0015168//glycerol transmembrane transporter activity;GO:0015250//water channel activity;GO:0015267//channel activity;GO:0016787//hydrolase activity;GO:0035379//carbon dioxide transmembrane transporter activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0003097//renal water transport;GO:0006508//proteolysis;GO:0006833//water transport;GO:0006972//hyperosmotic response;GO:0015793//glycerol transport;GO:0035378//carbon dioxide transmembrane transport;GO:0055085//transmembrane transport;GO:0071108//protein K48-linked deubiquitination;GO:0072488//ammonium transmembrane transport	--
ENSG00000250479	20.221	18.469	29.658	33.83	22.663	29.153	268	268	275	346	278	275	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10 [Source:HGNC Symbol;Acc:HGNC:15559]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K22759	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0061617//MICOS complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0006119//oxidative phosphorylation;GO:0007005//mitochondrion organization;GO:0030322//stabilization of membrane potential;GO:0031930//mitochondria-nucleus signaling pathway;GO:0051457//maintenance of protein location in nucleus;GO:0065003//protein-containing complex assembly;GO:0090144//mitochondrial nucleoid organization;GO:0099558//maintenance of synapse structure;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1903109//positive regulation of mitochondrial transcription;GO:1903852//positive regulation of cristae formation	--
ENSG00000250506	1.304	1.083	1.906	1.946	1.607	1.65	37	30	41	42	40	34	CDK3	cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0000082//G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008283//cell population proliferation;GO:0016310//phosphorylation;GO:0045023//G0 to G1 transition;GO:0045746//negative regulation of Notch signaling pathway;GO:0051301//cell division;GO:0051726//regulation of cell cycle	--
ENSG00000250510	2.804	2.926	3.4	2.821	2.583	2.867	131	130	102	87	107	97	GPR162	G protein-coupled receptor 162 [Source:HGNC Symbol;Acc:HGNC:16693]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000250565	0.979	0.739	0.856	0.602	1.024	0.953	35	26	25	16	30	26	ATP6V1E2	ATPase H+ transporting V1 subunit E2 [Source:HGNC Symbol;Acc:HGNC:18125]	Metabolism;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems	Global and overview maps;Infectious disease: viral;Transport and catabolism;Immune disease;Signal transduction;Energy metabolism;Nervous system;Infectious disease: bacterial;Infectious disease: bacterial;Excretory system	ko01100//Metabolic pathways;ko05165//Human papillomavirus infection;ko04145//Phagosome;ko05323//Rheumatoid arthritis;ko04150//mTOR signaling pathway;ko00190//Oxidative phosphorylation;ko04721//Synaptic vesicle cycle;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko05110//Vibrio cholerae infection;ko04966//Collecting duct acid secretion	K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150;K02150	"GO:0001669//acrosomal vesicle;GO:0005829//cytosol;GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain"	"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:0016241//regulation of macroautophagy;GO:1902600//proton transmembrane transport	--
ENSG00000250571	3.059	3.382	3.987	3.599	2.47	3.136	80.73	85.76	80.25	67.86	54.55	61	GLI4	GLI family zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:4320]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000250641	0	0	0	0	0	0	0	0	0	0	0	0	LY6G6F-LY6G6D	LY6G6F-LY6G6D readthrough [Source:HGNC Symbol;Acc:HGNC:38821]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000250644	20.009	19.47	20.381	18.084	19.008	17.117	909.2	865.01	644.49	614.66	698.47	549.54	CTSD	novel protein	Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing	Infectious disease: bacterial;Cardiovascular disease;Transport and catabolism;Cell growth and death;Transport and catabolism;Endocrine system;Signal transduction	ko05152//Tuberculosis;ko05415//Diabetic cardiomyopathy;ko04140//Autophagy - animal;ko04210//Apoptosis;ko04142//Lysosome;ko04915//Estrogen signaling pathway;ko04071//Sphingolipid signaling pathway	K01379;K01379;K01379;K01379;K01379;K01379;K01379	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0019538//protein metabolic process	--
ENSG00000250673	0	0	0	0	0	0	0	0	0	0	0	0	REELD1	reeler domain containing 1 [Source:HGNC Symbol;Acc:HGNC:53638]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000250709	0.071	0.188	0	0.202	0.197	0.222	3.01	8.03	0	6.35	7.09	6.88	CCDC169-SOHLH2	CCDC169-SOHLH2 readthrough [Source:HGNC Symbol;Acc:HGNC:38866]	-	-	-	-	-	GO:0046983//protein dimerization activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0048477//oogenesis"	bHLH
ENSG00000250719	0	0	0	0	0	0	0	0	0	0	0	0	P3R3URF	PIK3R3 upstream open reading frame [Source:HGNC Symbol;Acc:HGNC:53451]	-	-	-	-	GO:0005942//phosphatidylinositol 3-kinase complex	GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000250722	58.663	58.77	50.659	43.878	44.179	39.24	2457.22	2492.89	1576.8	1372.96	1566.24	1196.24	-	-	-	-	-	-	-	-	-	-
ENSG00000250741	0	0	0	0	0	0	0	0	0	0	0	0	NT5C1B-RDH14	NT5C1B-RDH14 readthrough [Source:HGNC Symbol;Acc:HGNC:38831]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Nucleotide metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism;ko00760//Nicotinate and nicotinamide metabolism	K01081;K01081;K01081;K01081	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity;GO:0016491//oxidoreductase activity	GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation;GO:0046085//adenosine metabolic process	--
ENSG00000250745	0	0	0	0	0	0	0	0	0	0	0	0	USP17L20	ubiquitin specific peptidase 17 like family member 20 [Source:HGNC Symbol;Acc:HGNC:44448]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000250782	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L14	TATA-box binding protein associated factor 11 like 14 [Source:HGNC Symbol;Acc:HGNC:53857]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000250799	0	0	0	0	0	0	0	0	0	0	0	0	PRODH2	proline dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:17325]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00330//Arginine and proline metabolism	K11394;K11394	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane	"GO:0004657//proline dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors;GO:0071949//FAD binding"	GO:0006560//proline metabolic process;GO:0006562//proline catabolic process;GO:0010133//proline catabolic process to glutamate	--
ENSG00000250803	0	0	0	0	0	0	0	0	0	0	0	0	ZNF474	zinc finger protein 474-like (LOC100505841)	-	-	-	-	-	-	-	--
ENSG00000250821	0	0	0	0	0	0	0	0	0	0	0	0	EXOC1L	exocyst complex component 1 like [Source:HGNC Symbol;Acc:HGNC:53433]	-	-	-	-	GO:0000145//exocyst;GO:0005886//plasma membrane	"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding"	GO:0006887//exocytosis;GO:0006893//Golgi to plasma membrane transport	--
ENSG00000250844	0	0	0	0	0	0	0	0	0	0	0	0	USP17L18	ubiquitin specific peptidase 17 like family member 18 [Source:HGNC Symbol;Acc:HGNC:44446]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0042981//regulation of apoptotic process	--
ENSG00000250913	0	0	0	0	0	0	0	0	0	0	0	0	USP17L23	ubiquitin specific peptidase 17 like family member 23 [Source:HGNC Symbol;Acc:HGNC:44451]	-	-	-	-	GO:0005634//nucleus;GO:0005783//endoplasmic reticulum	GO:0004843//thiol-dependent deubiquitinase	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination	--
ENSG00000251012	0	0	0	0	0	0	0	0	0	0	0	0	TEX55	novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000251039	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2D-40	immunoglobulin kappa variable 2D-40 [Source:HGNC Symbol;Acc:HGNC:5804]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000251154	0	0	0	0	0	0	0	0	0	0	0	0	PTTG1IP2	PTTG1IP family member 2 [Source:HGNC Symbol;Acc:HGNC:55318]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000251184	0	0	0.178	0	0.162	0	0	0	1.03	0	1.07	0	NUP188	novel protein	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14311;K14311	GO:0005634//nucleus;GO:0005643//nuclear pore	GO:0017056//structural constituent of nuclear pore	GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport	--
ENSG00000251192	1.026	0.923	0.873	0.81	0.427	0.69	45.46	56.23	32.94	18.09	17.73	32.8	ZNF674	zinc finger protein 674 [Source:HGNC Symbol;Acc:HGNC:17625]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000251201	1.127	0.89	0.631	0.945	1.299	0.766	81.52	64.78	33.6	50.34	79.16	40.34	TMED7-TICAM2	TMED7-TICAM2 readthrough [Source:HGNC Symbol;Acc:HGNC:33945]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0003953//NAD+ nucleosidase activity	GO:0007165//signal transduction;GO:0015031//protein transport	--
ENSG00000251246	0	0	0.122	0	0	0	0	0	1.95	0	0	0	EFNA3	novel ephrin-A4 (EFNA4) and ephrin-A3 (EFNA3) protein	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Signal transduction;Development and regeneration;Cancer: overview	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04360//Axon guidance;ko05206//MicroRNAs in cancer	K05462;K05462;K05462;K05462;K05462;K05462	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	GO:0046875//ephrin receptor binding	GO:0048013//ephrin receptor signaling pathway	--
ENSG00000251247	1.482	1.267	1.512	1.845	1.246	1.745	58	70	50	46	41	44	ZNF345	zinc finger protein 345 [Source:HGNC Symbol;Acc:HGNC:16367]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006359//regulation of transcription by RNA polymerase III;GO:0006366//transcription by RNA polymerase II;GO:0006383//transcription by RNA polymerase III;GO:0045944//positive regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000251258	0.076	0.025	0	0	0	0	3	1	0	0	0	0	RFPL4B	ret finger protein like 4B [Source:HGNC Symbol;Acc:HGNC:33264]	-	-	-	-	-	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000251287	0	0	0	0	0	0	0	0	0	0	0	0	ALG1L2	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:37258]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03842;K03842;K03842	GO:0005783//endoplasmic reticulum	GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006486//protein glycosylation;GO:0097502//mannosylation	--
ENSG00000251322	1.704	1.588	1.756	2.387	1.802	2.242	166	139	113	166	177	176	SHANK3	SH3 and multiple ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:14294]	Organismal Systems	Nervous system	ko04724//Glutamatergic synapse	K15009	GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043005//neuron projection;GO:0044309//neuron spine;GO:0045202//synapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0035255//ionotropic glutamate receptor binding;GO:0097110//scaffold protein binding;GO:0098919//structural constituent of postsynaptic density	"GO:0000165//MAPK cascade;GO:0001838//embryonic epithelial tube formation;GO:0007416//synapse assembly;GO:0007611//learning or memory;GO:0007612//learning;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0008306//associative learning;GO:0010467//gene expression;GO:0014009//glial cell proliferation;GO:0021773//striatal medium spiny neuron differentiation;GO:0032232//negative regulation of actin filament bundle assembly;GO:0035176//social behavior;GO:0035640//exploration behavior;GO:0035641//locomotory exploration behavior;GO:0040011//locomotion;GO:0045794//negative regulation of cell volume;GO:0048167//regulation of synaptic plasticity;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0048854//brain morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0051835//positive regulation of synapse structural plasticity;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060291//long-term synaptic potentiation;GO:0060292//long-term synaptic depression;GO:0060997//dendritic spine morphogenesis;GO:0060999//positive regulation of dendritic spine development;GO:0061001//regulation of dendritic spine morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0071625//vocalization behavior;GO:0097107//postsynaptic density assembly;GO:0097113//AMPA glutamate receptor clustering;GO:0097114//NMDA glutamate receptor clustering;GO:0097117//guanylate kinase-associated protein clustering;GO:0097396//response to interleukin-17;GO:0099562//maintenance of postsynaptic density structure;GO:1900271//regulation of long-term synaptic potentiation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1900451//positive regulation of glutamate receptor signaling pathway;GO:1900452//regulation of long-term synaptic depression;GO:1904717//regulation of AMPA glutamate receptor clustering;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2000821//regulation of grooming behavior;GO:2000822//regulation of behavioral fear response;GO:2000969//positive regulation of AMPA receptor activity"	--
ENSG00000251349	11.627	9.001	10.855	10.231	8.714	12.61	498.97	388.26	344.06	325.22	315.95	393.76	MSANTD3-TMEFF1	MSANTD3-TMEFF1 readthrough [Source:HGNC Symbol;Acc:HGNC:38838]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000251357	0	0.39	0.157	0	0.29	0	0	6.4	1.9	0	4.01	0	SLC2A11	novel protein	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015149//hexose transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0008645//hexose transmembrane transport;GO:0015749//monosaccharide transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000251369	1.526	2.021	2.437	1.609	2.026	1.631	111	145	78	76	113	96	ZNF550	zinc finger protein 550 [Source:HGNC Symbol;Acc:HGNC:28643]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000251380	0	0	0	0	0	0	0	0	0	0	0	0	DCANP1	dendritic cell associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:24459]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016604//nuclear body	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0007356//thorax and anterior abdomen determination;GO:0021559//trigeminal nerve development;GO:0021650//vestibulocochlear nerve formation;GO:0030432//peristalsis;GO:0031223//auditory behavior;GO:0035112//genitalia morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048634//regulation of muscle organ development;GO:0048806//genitalia development;GO:0048839//inner ear development;GO:0050885//neuromuscular process controlling balance;GO:0071626//mastication;GO:0090102//cochlea development;GO:0090103//cochlea morphogenesis;GO:0097094//craniofacial suture morphogenesis;GO:0098583//learned vocalization behavior;GO:1901078//negative regulation of relaxation of muscle;GO:1905747//negative regulation of saliva secretion;GO:1905748//hard palate morphogenesis	--
ENSG00000251493	2.457	1.795	2.547	2.306	2.59	2.216	128	94	98	89	114	84	FOXD1	forkhead box D1 [Source:HGNC Symbol;Acc:HGNC:3802]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0008301//DNA binding, bending;GO:0043565//sequence-specific DNA binding"	"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007411//axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0032275//luteinizing hormone secretion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060678//dichotomous subdivision of terminal units involved in ureteric bud branching;GO:0072076//nephrogenic mesenchyme development;GO:0072210//metanephric nephron development;GO:0072213//metanephric capsule development;GO:0072267//metanephric capsule specification;GO:0072268//pattern specification involved in metanephros development;GO:0090184//positive regulation of kidney development"	Fork_head
ENSG00000251503	0.236	0.14	0.511	1.377	0.039	0.455	4.78	2.01	5.39	18.22	1	3.92	CENPS-CORT	CENPS-CORT readthrough [Source:HGNC Symbol;Acc:HGNC:38843]	Genetic Information Processing	Replication and repair	ko03460//Fanconi anemia pathway	K11511	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005694//chromosome;GO:0071821//FANCM-MHF complex"	GO:0005179//hormone activity;GO:0046982//protein heterodimerization activity	GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0051301//cell division;GO:0051382//kinetochore assembly	--
ENSG00000251537	0.032	0	0	0	0	0	3.68	0	0	0	0	0	CDRT1	novel tripartite motif-containing 16 (TRIM16) and CMT1A duplicated region transcript 1 (CDRT1) protein	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane	GO:0005515//protein binding;GO:0008270//zinc ion binding	-	--
ENSG00000251546	0	0	0	0	0.455	0	0	0	0	0	3	0	IGKV1D-39	immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000251569	0.513	0.232	0.277	0	0.333	0.978	20.58	9.36	8.22	0	11.3	28.56	BBS5	novel protein	-	-	-	-	GO:0034464//BBSome	GO:0005515//protein binding	-	--
ENSG00000251608	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000251655	0	0	0	0	0	0	0	0	0	0	0	0	PRB1	proline rich protein BstNI subfamily 1 [Source:HGNC Symbol;Acc:HGNC:9337]	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13911	-	-	-	--
ENSG00000251664	1.28	1.721	1.552	1.161	1.541	2.248	143.35	193.81	128.39	96.34	145.82	183.29	PCDHA12	protocadherin alpha 12 [Source:HGNC Symbol;Acc:HGNC:8666]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000251692	0	0	0	0	0	0	0	0	0	0	0	0	PTX4	pentraxin 4 [Source:HGNC Symbol;Acc:HGNC:14171]	-	-	-	-	GO:0005576//extracellular region	GO:0046872//metal ion binding	-	--
ENSG00000253117	75.86	95.251	56.153	41.092	47.66	26.294	2813.39	3550.69	1538.07	1128.86	1493.32	709.53	OC90	otoconin 90 [Source:HGNC Symbol;Acc:HGNC:8100]	-	-	-	-	GO:0005575//cellular_component;GO:0005576//extracellular region;GO:0031012//extracellular matrix	GO:0003674//molecular_function;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006644//phospholipid metabolic process;GO:0008150//biological_process;GO:0016042//lipid catabolic process;GO:0045299//otolith mineralization;GO:0050482//arachidonic acid secretion	--
ENSG00000253148	0	0	0	0	0	0	0	0	0	0	0	0	RGS21	regulator of G protein signaling 21 [Source:HGNC Symbol;Acc:HGNC:26839]	-	-	-	-	GO:0005886//plasma membrane	GO:0003924//GTPase activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0009968//negative regulation of signal transduction	--
ENSG00000253159	0	0.018	0	0	0.022	0	0	1	0	0	1	0	PCDHGA12	"protocadherin gamma subfamily A, 12 [Source:HGNC Symbol;Acc:HGNC:8699]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253250	22.942	21.453	20.017	15.858	15.096	20.016	495.37	465.6	319.22	253.64	275.39	314.47	C8orf88	chromosome 8 open reading frame 88 [Source:HGNC Symbol;Acc:HGNC:44672]	-	-	-	-	GO:0005737//cytoplasm	GO:0008190//eukaryotic initiation factor 4E binding	GO:0045947//negative regulation of translational initiation	--
ENSG00000253251	0.72	0.249	0.805	0.718	0.481	0.473	23	8	19	17	13	11	SHLD3	shieldin complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:53826]	-	-	-	-	GO:0000785//chromatin;GO:0005694//chromosome;GO:0035861//site of double-strand break	GO:0005515//protein binding	GO:0002208//somatic diversification of immunoglobulins involved in immune response;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0043247//telomere maintenance in response to DNA damage;GO:0045830//positive regulation of isotype switching;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000253276	3.319	3.217	3.044	2.508	2.98	5	468	456	317	262	355	513	CCDC71L	coiled-coil domain containing 71 like [Source:HGNC Symbol;Acc:HGNC:26685]	-	-	-	-	-	-	GO:0044255//cellular lipid metabolic process;GO:0045600//positive regulation of fat cell differentiation	--
ENSG00000253293	0	0.061	0	0	0	0	0	2	0	0	0	0	HOXA10	homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K17443	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0007338//single fertilization;GO:0008584//male gonad development;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010468//regulation of gene expression;GO:0030326//embryonic limb morphogenesis;GO:0030850//prostate gland development;GO:0033574//response to testosterone;GO:0043627//response to estrogen;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0060065//uterus development"	Homeobox
ENSG00000253304	3.036	3.086	2.381	3.464	2.592	3.487	155.43	159.06	90.02	131.34	112.89	129.87	TMEM200B	transmembrane protein 200B [Source:HGNC Symbol;Acc:HGNC:33785]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000253305	47.502	49.618	51.181	53.434	54.707	47.835	4706.42	4941.55	3744.79	3921.45	4579.02	3448.44	PCDHGB6	"protocadherin gamma subfamily B, 6 [Source:HGNC Symbol;Acc:HGNC:8713]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253309	666.244	684.689	501.033	953.068	910.539	909.094	20812.31	20866.79	11505.45	21376.69	23366.8	20083.74	SERPINE3	serpin family E member 3 [Source:HGNC Symbol;Acc:HGNC:24774]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity	GO:0010466//negative regulation of peptidase activity;GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000253313	0	0.032	0	0	0	0.105	0	1	0	0	0	1	C1orf210	chromosome 1 open reading frame 210 [Source:HGNC Symbol;Acc:HGNC:28755]	-	-	-	-	GO:0005768//endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome	-	-	--
ENSG00000253352	36.741	35.185	31.944	25.158	29.927	28.344	5692	5479	3655	2887	3917	3195	TUG1	taurine up-regulated 1 [Source:HGNC Symbol;Acc:HGNC:26066]	-	-	-	-	-	-	-	--
ENSG00000253368	5.929	6.502	9.125	9.446	8.689	12.292	228	218	183	270	277	329	TRNP1	TMF1 regulated nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:34348]	-	-	-	-	GO:0000791//euchromatin;GO:0005634//nucleus	GO:0003677//DNA binding	GO:0007049//cell cycle;GO:0007399//nervous system development;GO:0021696//cerebellar cortex morphogenesis;GO:0042127//regulation of cell population proliferation;GO:0051726//regulation of cell cycle;GO:0061351//neural precursor cell proliferation	--
ENSG00000253457	0	0	0	0	0	0	0	0	0	0	0	0	SMIM18	small integral membrane protein 18 [Source:HGNC Symbol;Acc:HGNC:42973]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000253485	0	0	0	0.048	0	0	0	0	0	3.55	0	0	PCDHGA5	"protocadherin gamma subfamily A, 5 [Source:HGNC Symbol;Acc:HGNC:8703]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253506	0	0	0	0	0	0	0	0	0	0	0	0	NACA2	nascent polypeptide associated complex subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:23290]	Organismal Systems	Endocrine system	"ko04928//Parathyroid hormone synthesis, secretion and action"	K03626	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005854//nascent polypeptide-associated complex	GO:0051082//unfolded protein binding	GO:0006612//protein targeting to membrane;GO:0015031//protein transport	--
ENSG00000253537	0	0	0	0	0	0	0	0	0	0	0	0	PCDHGA7	"protocadherin gamma subfamily A, 7 [Source:HGNC Symbol;Acc:HGNC:8705]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253548	0	0	0	0	0	0	0	0	0	0	0	0	PYDC2	pyrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33512]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20911	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0002376//immune system process;GO:0006954//inflammatory response;GO:0009968//negative regulation of signal transduction;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0045087//innate immune response;GO:0050728//negative regulation of inflammatory response;GO:1900226//negative regulation of NLRP3 inflammasome complex assembly;GO:1901223//negative regulation of NIK/NF-kappaB signaling	--
ENSG00000253598	0.068	0	0.091	0.091	0.04	0.093	2	0	2	2	1	2	SLC10A5	solute carrier family 10 member 5 [Source:HGNC Symbol;Acc:HGNC:22981]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008508//bile acid:sodium symporter activity;GO:0015293//symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport	--
ENSG00000253626	0	0.012	0	0	0	0	0	1	0	0	0	0	EIF5AL1	eukaryotic translation initiation factor 5A like 1 [Source:HGNC Symbol;Acc:HGNC:17419]	-	-	-	-	GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane	GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0043022//ribosome binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0015031//protein transport;GO:0045901//positive regulation of translational elongation;GO:0045905//positive regulation of translational termination;GO:0051028//mRNA transport	--
ENSG00000253649	0.022	0	0.061	0.121	0.103	0.062	1	0	2	4	2	2	PRSS51	serine protease 51 [Source:HGNC Symbol;Acc:HGNC:37321]	-	-	-	-	GO:0005576//extracellular region	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000253710	13.116	11.291	11.083	10.36	9.719	9.917	1614.19	1418.08	998.11	897	897.11	925.04	ALG11	"ALG11 alpha-1,2-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:32456]"	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03844;K03844;K03844	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0004377//GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity"	GO:0006486//protein glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0097502//mannosylation	--
ENSG00000253719	22.322	22.928	24.621	23.983	22.966	25.724	3517	3631	2865	2799	3057	2949	ATXN7L3B	ataxin 7 like 3B [Source:HGNC Symbol;Acc:HGNC:37931]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0010468//regulation of gene expression	--
ENSG00000253729	22.087	19.179	18.979	13.856	16.982	15.481	6055	5315	3840	2836	3952	3108	PRKDC	"protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413]"	Cellular Processes;Genetic Information Processing	Cell growth and death;Replication and repair	ko04110//Cell cycle;ko03450//Non-homologous end-joining	K06642;K06642	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0016020//membrane;GO:0032040//small-subunit processome;GO:0032991//protein-containing complex;GO:0032993//protein-DNA complex;GO:0070418//DNA-dependent protein kinase complex;GO:0070419//nonhomologous end joining complex"	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004677//DNA-dependent protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0034511//U3 snoRNA binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding;GO:0106310//protein serine kinase activity	GO:0000460//maturation of 5.8S rRNA;GO:0000723//telomere maintenance;GO:0001756//somitogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0002218//activation of innate immune response;GO:0002326//B cell lineage commitment;GO:0002328//pro-B cell differentiation;GO:0002360//T cell lineage commitment;GO:0002376//immune system process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006310//DNA recombination;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0007420//brain development;GO:0007507//heart development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010212//response to ionizing radiation;GO:0010332//response to gamma radiation;GO:0016233//telomere capping;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030098//lymphocyte differentiation;GO:0031571//mitotic G1 DNA damage checkpoint signaling;GO:0031648//protein destabilization;GO:0032869//cellular response to insulin stimulus;GO:0033077//T cell differentiation in thymus;GO:0033151//V(D)J recombination;GO:0033152//immunoglobulin V(D)J recombination;GO:0033153//T cell receptor V(D)J recombination;GO:0034462//small-subunit processome assembly;GO:0035234//ectopic germ cell programmed cell death;GO:0042254//ribosome biogenesis;GO:0042752//regulation of circadian rhythm;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0044238//primary metabolic process;GO:0045087//innate immune response;GO:0045621//positive regulation of lymphocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045727//positive regulation of translation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048511//rhythmic process;GO:0048660//regulation of smooth muscle cell proliferation;GO:0050678//regulation of epithelial cell proliferation;GO:0097681//double-strand break repair via alternative nonhomologous end joining;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1905221//positive regulation of platelet formation;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining	--
ENSG00000253731	0.07	0.159	0.035	0.072	0.169	0.196	7	15.9	3	5.3	14.48	14.48	PCDHGA6	"protocadherin gamma subfamily A, 6 [Source:HGNC Symbol;Acc:HGNC:8704]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253767	0.066	0.125	0.099	0.12	0.105	0.123	8.85	13.39	9.13	8.85	9.74	8.88	PCDHGA8	"protocadherin gamma subfamily A, 8 [Source:HGNC Symbol;Acc:HGNC:8706]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253797	0	0.473	0	0	0.845	1.03	0	54.47	0	0	81.89	85.96	UTP14C	UTP14C small subunit processome component [Source:HGNC Symbol;Acc:HGNC:20321]	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14567	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0032040//small-subunit processome	GO:0005515//protein binding	GO:0006364//rRNA processing;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0042254//ribosome biogenesis;GO:0051321//meiotic cell cycle	--
ENSG00000253831	0	0	0	0	0	0	0	0	0	0	0	0	ETV3L	ETS variant transcription factor 3 like [Source:HGNC Symbol;Acc:HGNC:33834]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	ETS
ENSG00000253846	4.109	3.805	3.465	3.377	4.492	3.112	408.61	380.82	253.93	248.63	377.87	224.89	PCDHGA10	"protocadherin gamma subfamily A, 10 [Source:HGNC Symbol;Acc:HGNC:8697]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253873	0.531	0.55	0.297	0.844	0.502	0.428	52.63	54.91	21.11	57.46	42.08	27.61	PCDHGA11	"protocadherin gamma subfamily A, 11 [Source:HGNC Symbol;Acc:HGNC:8698]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253910	0.126	0.108	0.202	0.147	0.128	0.128	12.35	10.7	8	10.69	10.61	5	PCDHGB2	"protocadherin gamma subfamily B, 2 [Source:HGNC Symbol;Acc:HGNC:8709]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000253953	32.19	32.977	31.742	35.233	38.333	30.348	3176.08	3271.51	2313.17	2575.97	3196.46	2179.47	PCDHGB4	"protocadherin gamma subfamily B, 4 [Source:HGNC Symbol;Acc:HGNC:8711]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000253958	1.607	0.933	1.874	1.567	1.189	1.81	72	42	62	52	45	59	CLDN23	claudin 23 [Source:HGNC Symbol;Acc:HGNC:17591]	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//bicellular tight junction assembly	--
ENSG00000254004	5.763	4.001	3.187	3.021	2.95	3.82	595	420	242	232	272	299	ZNF260	zinc finger protein 260 [Source:HGNC Symbol;Acc:HGNC:13499]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000254087	18.577	27.532	21.533	15.861	19.689	15.583	1865	1827	1272	1012	1276	1012	LYN	"LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735]"	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Signal transduction;Immune system;Immune system;Immune system;Immune system;Infectious disease: bacterial;Nervous system	ko05169//Epstein-Barr virus infection;ko05417//Lipid and atherosclerosis;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko04662//B cell receptor signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04611//Platelet activation;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04730//Long-term depression	K05854;K05854;K05854;K05854;K05854;K05854;K05854;K05854;K05854;K05854;K05854;K05854	"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030061//mitochondrial crista;GO:0030666//endocytic vesicle membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031966//mitochondrial membrane;GO:0032991//protein-containing complex;GO:0034666//integrin alpha2-beta1 complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome;GO:0098978//glutamatergic synapse;GO:0099091//postsynaptic specialization, intracellular component"	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//signaling receptor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0043015//gamma-tubulin binding;GO:0043208//glycosphingolipid binding;GO:0044325//transmembrane transporter binding;GO:0044877//protein-containing complex binding;GO:0046875//ephrin receptor binding;GO:0051219//phosphoprotein binding;GO:0097110//scaffold protein binding;GO:0140031//phosphorylation-dependent protein binding	GO:0001782//B cell homeostasis;GO:0001817//regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0002513//tolerance induction to self antigen;GO:0002553//histamine secretion by mast cell;GO:0002576//platelet degranulation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0002902//regulation of B cell apoptotic process;GO:0006468//protein phosphorylation;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0006991//response to sterol depletion;GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0008285//negative regulation of cell population proliferation;GO:0009410//response to xenobiotic stimulus;GO:0009636//response to toxic substance;GO:0009725//response to hormone;GO:0009743//response to carbohydrate;GO:0010976//positive regulation of neuron projection development;GO:0014003//oligodendrocyte development;GO:0014070//response to organic cyclic compound;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030097//hemopoiesis;GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0030335//positive regulation of cell migration;GO:0030889//negative regulation of B cell proliferation;GO:0031175//neuron projection development;GO:0031295//T cell costimulation;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0032868//response to insulin;GO:0033003//regulation of mast cell activation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0034605//cellular response to heat;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043200//response to amino acid;GO:0043304//regulation of mast cell degranulation;GO:0043407//negative regulation of MAP kinase activity;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045087//innate immune response;GO:0045646//regulation of erythrocyte differentiation;GO:0046777//protein autophosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0048678//response to axon injury;GO:0050727//regulation of inflammatory response;GO:0050777//negative regulation of immune response;GO:0050853//B cell receptor signaling pathway;GO:0050855//regulation of B cell receptor signaling pathway;GO:0050900//leukocyte migration;GO:0051272//positive regulation of cellular component movement;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0060252//positive regulation of glial cell proliferation;GO:0060369//positive regulation of Fc receptor mediated stimulatory signaling pathway;GO:0060397//growth hormone receptor signaling pathway via JAK-STAT;GO:0070304//positive regulation of stress-activated protein kinase signaling cascade;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070447//positive regulation of oligodendrocyte progenitor proliferation;GO:0070667//negative regulation of mast cell proliferation;GO:0070668//positive regulation of mast cell proliferation;GO:0071300//cellular response to retinoic acid;GO:0090025//regulation of monocyte chemotaxis;GO:0090330//regulation of platelet aggregation;GO:0097028//dendritic cell differentiation;GO:1902532//negative regulation of intracellular signal transduction;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:2000670//positive regulation of dendritic cell apoptotic process	--
ENSG00000254093	4.599	6.458	3.955	4.07	4.751	5.73	116	153	90.71	93	102	95	PINX1	PIN2 (TERF1) interacting telomerase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:30046]	-	-	-	-	"GO:0000228//nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005819//spindle"	GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0010521//telomerase inhibitor activity;GO:0044877//protein-containing complex binding;GO:0070034//telomerase RNA binding	"GO:0007004//telomere maintenance via telomerase;GO:0007080//mitotic metaphase plate congression;GO:0008285//negative regulation of cell population proliferation;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0051972//regulation of telomerase activity;GO:0051974//negative regulation of telomerase activity;GO:0070198//protein localization to chromosome, telomeric region;GO:0090069//regulation of ribosome biogenesis;GO:1902570//protein localization to nucleolus;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:1904744//positive regulation of telomeric DNA binding;GO:1904751//positive regulation of protein localization to nucleolus"	--
ENSG00000254122	6.704	7.264	7.668	7.113	8.313	7.102	656.28	712.76	539.89	514.83	660.53	501.71	PCDHGB7	"protocadherin gamma subfamily B, 7 [Source:HGNC Symbol;Acc:HGNC:8714]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000254126	0	0	0	0	0	0	0	0	0	0	0	0	CD8B2	CD8b2 molecule [Source:HGNC Symbol;Acc:HGNC:1708]	Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: bacterial;Immune system;Signaling molecules and interaction;Immune disease;Immune system;Immune system	ko05135//Yersinia infection;ko04640//Hematopoietic cell lineage;ko04514//Cell adhesion molecules;ko05340//Primary immunodeficiency;ko04660//T cell receptor signaling pathway;ko04612//Antigen processing and presentation	K06459;K06459;K06459;K06459;K06459;K06459	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015026//coreceptor activity;GO:0042288//MHC class I protein binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0050776//regulation of immune response	--
ENSG00000254167	0	0	0	0	0	0	0	0	0	0	0	0	IGHV8-51-1	immunoglobulin heavy variable IGHV8-51-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5704]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	-	-	-	--
ENSG00000254206	1.344	0.864	1.285	1.126	1.39	1.428	101.85	65.78	71.91	63.22	88.98	78.72	NPIPB11	nuclear pore complex interacting protein family member B11 [Source:HGNC Symbol;Acc:HGNC:37453]	-	-	-	-	GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000254221	0.071	0.13	0.025	0.1	0.127	0.051	7.04	7	1	4	10.59	2	PCDHGB1	"protocadherin gamma subfamily B, 1 [Source:HGNC Symbol;Acc:HGNC:8708]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030426//growth cone	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000254245	0	0	0.025	0	0	0	0	0	1.04	0	0	0	PCDHGA3	"protocadherin gamma subfamily A, 3 [Source:HGNC Symbol;Acc:HGNC:8701]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008333//endosome to lysosome transport;GO:0060989//lipid tube assembly involved in organelle fusion	--
ENSG00000254402	5.013	5.014	6.037	5.48	5.456	5.009	183.23	184.18	162.96	148.36	168.47	133.2	LRRC24	leucine rich repeat containing 24 [Source:HGNC Symbol;Acc:HGNC:28947]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix	GO:0005515//protein binding	GO:0051965//positive regulation of synapse assembly	--
ENSG00000254413	0.512	0.457	0.776	0.317	0.789	0.421	29.88	26.85	33.49	13.73	38.94	17.9	CHKB-CPT1B	CHKB-CPT1B readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41998]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism	ko01100//Metabolic pathways;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism	K14156;K14156;K14156	GO:0005737//cytoplasm	GO:0004103//choline kinase activity;GO:0004305//ethanolamine kinase activity;GO:0016301//kinase activity	GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0016310//phosphorylation;GO:0046474//glycerophospholipid biosynthetic process	--
ENSG00000254415	0	0	0	0	0	0	0	0	0	0	0	0	SIGLEC14	sialic acid binding Ig like lectin 14 [Source:HGNC Symbol;Acc:HGNC:32926]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000254440	0	0	0	0	0	0	0	0	0	0	0	0	PBOV1	prostate and breast cancer overexpressed 1 [Source:HGNC Symbol;Acc:HGNC:21079]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0034451//centriolar satellite	-	-	--
ENSG00000254445	0	0	0	0	0	0	0	0	0	0	0	0	HSPB2-C11orf52	HSPB2-C11orf52 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41996]	Human Diseases	Cancer: overview	ko05205//Proteoglycans in cancer	K09543	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005212//structural constituent of eye lens	-	--
ENSG00000254466	0	0	0	0	0	0	0	0	0	0	0	0	OR4D10	olfactory receptor family 4 subfamily D member 10 [Source:HGNC Symbol;Acc:HGNC:15173]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000254469	0.519	0.37	0.161	0.21	0.083	0.334	12.66	5.72	4	3.26	7	5	XNDC1N	"XRCC1 N-terminal domain containing 1, N-terminal like [Source:HGNC Symbol;Acc:HGNC:54661]"	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle	GO:0003684//damaged DNA binding	GO:0000012//single strand break repair	--
ENSG00000254470	5.36	5.518	5.368	5.884	6.303	6.873	776	803	574	631	771	724	AP5B1	adaptor related protein complex 5 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:25104]	-	-	-	-	GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0030119//AP-type membrane coat adaptor complex;GO:0044599//AP-5 adaptor complex	GO:0005515//protein binding	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport	--
ENSG00000254505	12.907	18.009	15.477	13.993	11.294	12.673	263	370	236	207	192.79	191	CHMP4A	charged multivesicular body protein 4A [Source:HGNC Symbol;Acc:HGNC:20274]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12194;K12194	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030496//midbody;GO:0030659//cytoplasmic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051117//ATPase binding	GO:0001778//plasma membrane repair;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0006900//vesicle budding from membrane;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007080//mitotic metaphase plate congression;GO:0010324//membrane invagination;GO:0015031//protein transport;GO:0016032//viral process;GO:0016236//macroautophagy;GO:0031468//nuclear membrane reassembly;GO:0032511//late endosome to vacuole transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046761//viral budding from plasma membrane;GO:0051258//protein polymerization;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097320//plasma membrane tubulation;GO:0097352//autophagosome maturation;GO:0140014//mitotic nuclear division;GO:1901215//negative regulation of neuron death;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1902902//negative regulation of autophagosome assembly	--
ENSG00000254521	0	0	0	0	0	0	0	0	0	0	0	0	SIGLEC12	sialic acid binding Ig like lectin 12 [Source:HGNC Symbol;Acc:HGNC:15482]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000254535	1.141	1.01	0.602	0.757	1.076	1.05	118	105	46	58	94	79	PABPC4L	poly(A) binding protein cytoplasmic 4 like [Source:HGNC Symbol;Acc:HGNC:31955]	Genetic Information Processing;Genetic Information Processing	"Translation;Folding, sorting and degradation"	ko03015//mRNA surveillance pathway;ko03018//RNA degradation	K13126;K13126	GO:0005634//nucleus;GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:1990904//ribonucleoprotein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008143//poly(A) binding;GO:0008266//poly(U) RNA binding	-	--
ENSG00000254536	0	0.366	0.123	0.185	0	0	0	18.02	2.14	3.23	0	0	PAOX	novel protein	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K00308	-	GO:0016491//oxidoreductase activity	-	--
ENSG00000254550	0	0	0	0	0	0	0	0	0	0	0	0	OMP	olfactory marker protein [Source:HGNC Symbol;Acc:HGNC:8136]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0045202//synapse	GO:0042277//peptide binding	GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007608//sensory perception of smell;GO:0022008//neurogenesis;GO:0050896//response to stimulus	--
ENSG00000254553	0.016	0.312	0	0.081	0	0	1.15	22.41	0	4.31	0	0	ZBTB8B	novel transcript	-	-	-	-	-	-	-	ZBTB
ENSG00000254585	2.076	2.399	2.69	3.074	2.669	2.424	186	216	178	204	202	158	MAGEL2	MAGE family member L2 [Source:HGNC Symbol;Acc:HGNC:6814]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0030904//retromer complex	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0042147//retrograde transport, endosome to Golgi;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0051127//positive regulation of actin nucleation;GO:0070534//protein K63-linked ubiquitination"	--
ENSG00000254598	0	0	0.098	0	0	0	0	0	1.97	0	0	0	CSNK2A3	casein kinase 2 alpha 3 [Source:HGNC Symbol;Acc:HGNC:2458]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Infectious disease: viral;Cancer: overview;Translation;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05020//Prion disease;ko04064//NF-kappa B signaling pathway;ko04310//Wnt signaling pathway;ko05162//Measles;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko03008//Ribosome biogenesis in eukaryotes;ko04137//Mitophagy - animal;ko04520//Adherens junction	K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097;K03097	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005956//protein kinase CK2 complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0008284//positive regulation of cell population proliferation;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0045732//positive regulation of protein catabolic process;GO:0051726//regulation of cell cycle	--
ENSG00000254636	0.118	0.352	0.319	0	0.07	0.081	2	6	4	0	1	1	ARMS2	age-related maculopathy susceptibility 2 [Source:HGNC Symbol;Acc:HGNC:32685]	-	-	-	-	GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0001895//retina homeostasis	--
ENSG00000254647	0	0	0	0	0	0	0	0	0	0	0	0	INS	insulin [Source:HGNC Symbol;Acc:HGNC:6081]	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Signal transduction;Transport and catabolism;Cell growth and death;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine system;Endocrine and metabolic disease;Cancer: specific types;Aging;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine and metabolic disease;Endocrine and metabolic disease;Excretory system;Endocrine and metabolic disease	ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko05215//Prostate cancer;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04917//Prolactin signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04930//Type II diabetes mellitus;ko04940//Type I diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption;ko04950//Maturity onset diabetes of the young	K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526	GO:0000139//Golgi membrane;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0030133//transport vesicle;GO:0031904//endosome lumen;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0034774//secretory granule lumen	GO:0002020//protease binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0042802//identical protein binding	"GO:0001819//positive regulation of cytokine production;GO:0002674//negative regulation of acute inflammatory response;GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006953//acute-phase response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell population proliferation;GO:0008286//insulin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010750//positive regulation of nitric oxide mediated signal transduction;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0022898//regulation of transmembrane transporter activity;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0031954//positive regulation of protein autophosphorylation;GO:0032148//activation of protein kinase B activity;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032880//regulation of protein localization;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0038060//nitric oxide-cGMP-mediated signaling pathway;GO:0042060//wound healing;GO:0042177//negative regulation of protein catabolic process;GO:0042311//vasodilation;GO:0042593//glucose homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0045597//positive regulation of cell differentiation;GO:0045721//negative regulation of gluconeogenesis;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0045818//negative regulation of glycogen catabolic process;GO:0045821//positive regulation of glycolytic process;GO:0045840//positive regulation of mitotic nuclear division;GO:0045861//negative regulation of proteolysis;GO:0045922//negative regulation of fatty acid metabolic process;GO:0046326//positive regulation of glucose import;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046631//alpha-beta T cell activation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0048167//regulation of synaptic plasticity;GO:0050708//regulation of protein secretion;GO:0050709//negative regulation of protein secretion;GO:0050714//positive regulation of protein secretion;GO:0050890//cognition;GO:0050995//negative regulation of lipid catabolic process;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0055089//fatty acid homeostasis;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0060267//positive regulation of respiratory burst;GO:0090277//positive regulation of peptide hormone secretion;GO:0090336//positive regulation of brown fat cell differentiation;GO:1900182//positive regulation of protein localization to nucleus;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:1902952//positive regulation of dendritic spine maintenance;GO:1903076//regulation of protein localization to plasma membrane;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903576//response to L-arginine;GO:1990535//neuron projection maintenance;GO:2000252//negative regulation of feeding behavior"	--
ENSG00000254656	0	0	0	0	0	0	0	0	0	0	0	0	RTL1	retrotransposon Gag like 1 [Source:HGNC Symbol;Acc:HGNC:14665]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000254658	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000254673	0	0	0	0	0	0.35	0	0	0	0	0	3.29	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000254685	8.109	4.875	4.888	2.823	2.309	3.698	311.71	286.87	189.56	147.94	156.93	163.71	FPGT	fucose-1-phosphate guanylyltransferase [Source:HGNC Symbol;Acc:HGNC:3825]	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism;ko00051//Fructose and mannose metabolism	K00976;K00976;K00976	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005525//GTP binding;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016779//nucleotidyltransferase activity;GO:0047341//fucose-1-phosphate guanylyltransferase activity"	GO:0006004//fucose metabolic process	--
ENSG00000254692	0	0	0	0	0.366	0	0	0	0	0	17.57	0	TM9SF1	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0016032//viral process;GO:0061952//midbody abscission;GO:0140014//mitotic nuclear division	--
ENSG00000254706	3.187	3.122	5.406	4.021	4.204	5.47	38.93	38.13	49.64	38.6	42.54	50.5	C1orf226	novel protein	Organismal Systems	Environmental adaptation	ko04713//Circadian entrainment	K16513	-	-	-	--
ENSG00000254709	0	0	0	0	0.371	0	0	0	0	0	8.46	0	IGLL5	immunoglobulin lambda like polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:38476]	Human Diseases	Immune disease	ko05340//Primary immunodeficiency	K06554	"GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating;GO:0070062//extracellular exosome"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000254726	6.613	6.208	5.526	3.851	4.762	4.584	904	853	558	390	550	456	MEX3A	mex-3 RNA binding family member A [Source:HGNC Symbol;Acc:HGNC:33482]	-	-	-	-	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0046872//metal ion binding	-	--
ENSG00000254732	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein, C11orf31-CTNND1 readthrough"	-	-	-	-	-	-	-	--
ENSG00000254737	0	0	0	0	0	0	0	0	0	0	0	0	OR10G4	olfactory receptor family 10 subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:14809]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000254772	1253.585	1294.85	1286.695	1441.704	1308.64	1209.833	37598.69	39035.98	28502.46	32029.91	33160.45	26402.12	EEF1G	eukaryotic translation elongation factor 1 gamma [Source:HGNC Symbol;Acc:HGNC:3213]	Human Diseases	Infectious disease: bacterial	ko05134//Legionellosis	K03233	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular exosome	GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0045296//cadherin binding	GO:0006412//translation;GO:0006414//translational elongation;GO:0006749//glutathione metabolic process;GO:0009615//response to virus	--
ENSG00000254788	0.252	0.426	0.776	0.657	0.113	0.352	3.07	5.01	7.1	6.05	1	3.12	CKLF-CMTM1	CKLF-CMTM1 readthrough [Source:HGNC Symbol;Acc:HGNC:39977]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000254806	1.059	1.188	1.411	1.405	3.382	0.58	24.69	25.41	14.57	19.76	42.36	5.9	SYS1-DBNDD2	SYS1-DBNDD2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:33535]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000254827	0.425	0.124	0.271	0.472	0.65	0.446	17	5	8	14	22	13	SLC22A18AS	solute carrier family 22 member 18 antisense [Source:HGNC Symbol;Acc:HGNC:10965]	-	-	-	-	GO:0005575//cellular_component	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000254834	0	0	0	0	0	0	0	0	0	0	0	0	OR5M10	olfactory receptor family 5 subfamily M member 10 [Source:HGNC Symbol;Acc:HGNC:15290]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000254852	0.67	0.41	0	0.2	0.464	0.984	14.3	8.73	0	3.24	8.57	15.29	NPIPA2	nuclear pore complex interacting protein family member A2 [Source:HGNC Symbol;Acc:HGNC:41979]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000254858	9.196	8.389	9.473	9.94	9.438	10.204	301	276	229	241	261	243	MPV17L2	MPV17 mitochondrial inner membrane protein like 2 [Source:HGNC Symbol;Acc:HGNC:28177]	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13348	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0061668//mitochondrial ribosome assembly;GO:0070131//positive regulation of mitochondrial translation	--
ENSG00000254870	0.451	0.892	0.611	0.765	0.396	0.777	19.08	37.94	19.07	23.96	14.14	23.92	ATP6V1G2-DDX39B	ATP6V1G2-DDX39B readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41999]	-	-	-	-	GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0030285//integral component of synaptic vesicle membrane	"GO:0016887//ATP hydrolysis activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism"	GO:0006811//ion transport;GO:1902600//proton transmembrane transport	--
ENSG00000254901	6.201	6.272	5.884	6.314	5.059	5.871	161.45	148.93	104.98	120.59	106.85	110.88	BORCS8	BLOC-1 related complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:37247]	-	-	-	-	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0098574//cytoplasmic side of lysosomal membrane;GO:0099078//BORC complex	GO:0005515//protein binding	GO:0007507//heart development;GO:0032418//lysosome localization;GO:0051036//regulation of endosome size;GO:0062196//regulation of lysosome size;GO:0072384//organelle transport along microtubule	--
ENSG00000254959	0	0	0	0	0	0.231	0	0	0	0	0	10.04	INMT-MINDY4	INMT-MINDY4 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41995]	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00380//Tryptophan metabolism;ko00450//Selenocompound metabolism	K00562;K00562;K00562	-	GO:0008168//methyltransferase activity;GO:0016740//transferase activity	-	--
ENSG00000254979	0	0	0.192	0	0	0.124	0	0	2	0	0	1	PRG2	novel protein	Human Diseases	Immune disease	ko05310//Asthma	K10786	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006955//immune response	--
ENSG00000254986	10.696	12.055	10.877	10.604	11.507	9.66	601	587	409	402	517.79	358	DPP3	dipeptidyl peptidase 3 [Source:HGNC Symbol;Acc:HGNC:3008]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity	GO:0006508//proteolysis	--
ENSG00000254995	0	0	0	0	0	0	0	0	0	0	0	0	STX16-NPEPL1	STX16-NPEPL1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41993]	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08489	GO:0016020//membrane;GO:0031201//SNARE complex	GO:0005484//SNAP receptor activity	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion	--
ENSG00000254996	4.375	5.916	4.02	2.78	3.101	2.864	673.24	914.79	455.87	320.57	384.98	307.78	ANKHD1-EIF4EBP3	ANKHD1-EIF4EBP3 readthrough [Source:HGNC Symbol;Acc:HGNC:33530]	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000254997	0.041	0	0	0	0	0	1	0	0	0	0	0	KRTAP5-9	keratin associated protein 5-9 [Source:HGNC Symbol;Acc:HGNC:23604]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0008544//epidermis development	--
ENSG00000254999	74.12	67.943	70.897	79.518	65.897	77.899	1768	1629	1249	1405	1328	1352	BRK1	BRICK1 subunit of SCAR/WAVE actin nucleating complex [Source:HGNC Symbol;Acc:HGNC:23057]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04810//Regulation of actin cytoskeleton	K05752;K05752;K05752	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0070062//extracellular exosome	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0044877//protein-containing complex binding	GO:0001701//in utero embryonic development;GO:0007015//actin filament organization;GO:0008064//regulation of actin polymerization or depolymerization;GO:0008284//positive regulation of cell population proliferation;GO:0010592//positive regulation of lamellipodium assembly;GO:0016601//Rac protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0031334//positive regulation of protein-containing complex assembly;GO:0048870//cell motility;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation	--
ENSG00000255009	0	0	0	0	0	0	0	0	0	0	0	0	UBTFL1	upstream binding transcription factor like 1 [Source:HGNC Symbol;Acc:HGNC:14533]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003677//DNA binding;GO:0005515//protein binding	GO:0001832//blastocyst growth;GO:0007566//embryo implantation;GO:0010468//regulation of gene expression	HMG
ENSG00000255012	0	0	0	0	0	0	0	0	0	0	0	0	OR5M1	olfactory receptor family 5 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:8352]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255054	0	0	0	0	0	0	0	0	0	0	0	0	SELENON	novel protein	-	-	-	-	-	-	-	--
ENSG00000255071	0	0	0	0	0	0	0	0	0	0	0	0	SAA2-SAA4	SAA2-SAA4 readthrough [Source:HGNC Symbol;Acc:HGNC:39550]	-	-	-	-	GO:0005576//extracellular region;GO:0034364//high-density lipoprotein particle	-	GO:0006953//acute-phase response	--
ENSG00000255072	20.759	20.873	19.718	20.976	19.457	19.459	564.5	570.5	396	422.5	447	385	PIGY	phosphatidylinositol glycan anchor biosynthesis class Y [Source:HGNC Symbol;Acc:HGNC:28213]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K11001;K11001	GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity	GO:0006506//GPI anchor biosynthetic process	--
ENSG00000255073	0	0.255	0	0.077	0	0.117	0	9.49	0	2.75	0	3.17	ZFP91-CNTF	ZFP91-CNTF readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:33441]	-	-	-	-	-	-	-	zf-C2H2
ENSG00000255104	0	0	0	0	0	0	0	0	0	0	0	0	ZNF286A-TBC1D26	ZNF286A-TBC1D26 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:55384]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	zf-C2H2
ENSG00000255112	21.784	21.799	20.862	20.329	18.896	20.521	1370	1378	969	947	1004	939	CHMP1B	charged multivesicular body protein 1B [Source:HGNC Symbol;Acc:HGNC:24287]	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12197;K12197	GO:0000421//autophagosome membrane;GO:0000776//kinetochore;GO:0000815//ESCRT III complex;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body;GO:0005828//kinetochore microtubule;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030117//membrane coat;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular exosome;GO:1904930//amphisome membrane	GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0090541//MIT domain binding	GO:0001778//plasma membrane repair;GO:0006914//autophagy;GO:0006997//nucleus organization;GO:0007034//vacuolar transport;GO:0007049//cell cycle;GO:0007080//mitotic metaphase plate congression;GO:0010824//regulation of centrosome duplication;GO:0015031//protein transport;GO:0031468//nuclear membrane reassembly;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0036258//multivesicular body assembly;GO:0039702//viral budding via host ESCRT complex;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045184//establishment of protein localization;GO:0045324//late endosome to vacuole transport;GO:0046761//viral budding from plasma membrane;GO:0051301//cell division;GO:0051469//vesicle fusion with vacuole;GO:0060548//negative regulation of cell death;GO:0061763//multivesicular body-lysosome fusion;GO:0061952//midbody abscission;GO:0071985//multivesicular body sorting pathway;GO:0090148//membrane fission;GO:0097352//autophagosome maturation;GO:1901673//regulation of mitotic spindle assembly;GO:1902774//late endosome to lysosome transport;GO:1904903//ESCRT III complex disassembly	--
ENSG00000255150	0.723	0.196	0.178	0.133	0.272	0.587	22	6	4	3	7	13	EID3	EP300 interacting inhibitor of differentiation 3 [Source:HGNC Symbol;Acc:HGNC:32961]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0030915//Smc5-Smc6 complex"	GO:0005515//protein binding	GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0016925//protein sumoylation;GO:0032204//regulation of telomere maintenance	--
ENSG00000255151	0	0	0	0	0	0	0	0	0	0	0	0	GLYATL1B	glycine-N-acyltransferase like 1B [Source:HGNC Symbol;Acc:HGNC:37865]	-	-	-	-	GO:0005739//mitochondrion	GO:0016410//N-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0047946//glutamine N-acyltransferase activity;GO:0047961//glycine N-acyltransferase activity	GO:0006541//glutamine metabolic process	--
ENSG00000255152	0.122	0.189	0.761	0.373	0.278	0.635	2.41	10.21	13.76	5.44	10.37	11.85	MSH5-SAPCD1	MSH5-SAPCD1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41994]	-	-	-	-	GO:0005634//nucleus;GO:0032301//MutSalpha complex	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0030983//mismatched DNA binding	GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0006974//cellular response to DNA damage stimulus	--
ENSG00000255154	3.717	3.913	5.199	4.462	4.356	2.53	117.66	173.78	166.38	132.24	138.51	67.93	HTD2	hydroxyacyl-thioester dehydratase type 2 [Source:HGNC Symbol;Acc:HGNC:53111]	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko01212//Fatty acid metabolism;ko00061//Fatty acid biosynthesis	K22540;K22540;K22540	GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0004317//3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;GO:0008659//(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity;GO:0008693//3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity;GO:0016829//lyase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0019171//3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity;GO:0047451//3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0046949//fatty-acyl-CoA biosynthetic process	--
ENSG00000255181	0	0	0	0	0	0	0	0	0	0	0	0	CCDC166	coiled-coil domain containing 166 [Source:HGNC Symbol;Acc:HGNC:41910]	-	-	-	-	-	-	-	--
ENSG00000255192	0	0.049	0	0	0	0	0	1.93	0	0	0	0	NANOGP8	Nanog homeobox retrogene P8 [Source:HGNC Symbol;Acc:HGNC:23106]	Human Diseases;Cellular Processes	Cancer: overview;Cellular community - eukaryotes	ko05205//Proteoglycans in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells	K10164;K10164	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:1902808//positive regulation of cell cycle G1/S phase transition"	Homeobox
ENSG00000255223	0	0	0	0	0	0	0	0	0	0	0	0	OR5M11	olfactory receptor family 5 subfamily M member 11 [Source:HGNC Symbol;Acc:HGNC:15291]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255245	0	0	0	0	0	0	0	0	0	0	0	0	FXYD6-FXYD2	FXYD6-FXYD2 readthrough [Source:HGNC Symbol;Acc:HGNC:39978]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0043269//regulation of ion transport	--
ENSG00000255251	0	0	0	0	0	0	0	0	0	0	0	0	PRR23D1	proline rich 23 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:49420]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000255274	0	0	0	0	0	0	0	0	0	0	0	0	SMIM35	small integral membrane protein 35 [Source:HGNC Symbol;Acc:HGNC:44179]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000255292	0	0	0	0	0	0	0	0	0	0	0	0	SDHD	novel transcript	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237;K00237	GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding	GO:0006099//tricarboxylic acid cycle	--
ENSG00000255298	0	0	0	0	0.099	0	0	0	0	0	2	0	OR8G5	olfactory receptor family 8 subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:19622]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255302	142.365	128.894	131.578	136.585	123.752	142.785	6024	5482	4112	4281	4424	4396	EID1	EP300 interacting inhibitor of differentiation 1 [Source:HGNC Symbol;Acc:HGNC:1191]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0035034//histone acetyltransferase regulator activity;GO:0035035//histone acetyltransferase binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0007049//cell cycle;GO:0030154//cell differentiation;GO:0035065//regulation of histone acetylation;GO:0045595//regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000255307	0	0	0	0	0	0	0	0	0	0	0	0	OR52B2	olfactory receptor family 52 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:15207]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255330	0.058	0.019	0.019	0	0.065	0	4	1.36	1	0	6.08	0	SOGA3	SOGA family member 3 [Source:NCBI gene (formerly Entrezgene);Acc:387104]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0010506//regulation of autophagy	--
ENSG00000255339	1.665	1.519	0.831	2.764	0.781	2.707	40.12	33.01	11.82	44.5	19.94	35.26	NDUFB8	"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa (NDUFB8) and SEC31 homolog B (S. cerevisiae) (SEC31B) readthrough"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964;K03964	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane	-	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone"	--
ENSG00000255346	0	0.101	0.125	0.057	0.025	0	0	4	3	2	1	0	NOX5	NADPH oxidase 5 [Source:HGNC Symbol;Acc:HGNC:14874]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015252//proton channel activity;GO:0016175//superoxide-generating NAD(P)H oxidase activity;GO:0016491//oxidoreductase activity;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding	GO:0001525//angiogenesis;GO:0001819//positive regulation of cytokine production;GO:0001935//endothelial cell proliferation;GO:0006811//ion transport;GO:0006915//apoptotic process;GO:0042554//superoxide anion generation;GO:0043012//regulation of fusion of sperm to egg plasma membrane;GO:0061640//cytoskeleton-dependent cytokinesis;GO:1902600//proton transmembrane transport;GO:2000379//positive regulation of reactive oxygen species metabolic process	--
ENSG00000255359	0	0	0	0	0	0	0	0	0	0	0	0	CCDC179	coiled-coil domain containing 179 [Source:HGNC Symbol;Acc:HGNC:44653]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000255374	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R43	taste 2 receptor member 43 [Source:HGNC Symbol;Acc:HGNC:18875]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0042995//cell projection;GO:0060170//ciliary membrane	GO:0004930//G protein-coupled receptor activity;GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000255378	0	0	0	0	0	0	0	0	0	0	0	0	PRR23D2	proline rich 23 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:49396]	-	-	-	-	-	-	-	--
ENSG00000255393	0	0	0	0	0	0	0	0	0	0	0	0	OOSP4B	oocyte secreted protein family member 4B [Source:HGNC Symbol;Acc:HGNC:53905]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000255398	0	0	0	0	0	0	0	0	0	0	0	0	HCAR3	hydroxycarboxylic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:16824]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K08402	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000255408	0.105	0.21	0.293	0.158	0.176	0.137	10	22.47	23.09	12.3	14.66	10.4	PCDHA3	protocadherin alpha 3 [Source:HGNC Symbol;Acc:HGNC:8669]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development	--
ENSG00000255423	0.287	0.171	0	0.039	0.374	0.237	10	6	0	1	11	6	EBLN2	endogenous Bornavirus like nucleoprotein 2 [Source:HGNC Symbol;Acc:HGNC:25493]	-	-	-	-	-	-	-	--
ENSG00000255425	0	0	0	0	0	0	0	0	0	0	0	0	OR8G3P	olfactory receptor family 8 subfamily G member 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:14698]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255432	0	0.189	0.117	0.24	0	0.144	0	2.27	1.03	2.13	0	1.25	C11orf98	novel protein	-	-	-	-	-	-	-	--
ENSG00000255439	13.36	12.825	12.007	13.113	15.506	11.915	200.9	193.85	133.36	146.07	197	130.37	VKORC1	"novel protein, VKORC1 and PRSS53 readthrough"	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00130//Ubiquinone and other terpenoid-quinone biosynthesis	K05357;K05357	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0004252//serine-type endopeptidase activity;GO:0016491//oxidoreductase activity;GO:0016900//oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor;GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0048038//quinone binding"	GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0042373//vitamin K metabolic process	--
ENSG00000255501	0	0	0	0	0	0	0	0	0	0	0	0	CARD18	caspase recruitment domain family member 18 [Source:HGNC Symbol;Acc:HGNC:28861]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K12806	GO:0032991//protein-containing complex	GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0030414//peptidase inhibitor activity;GO:0050700//CARD domain binding;GO:0089720//caspase binding	GO:0006954//inflammatory response;GO:0010466//negative regulation of peptidase activity;GO:0032091//negative regulation of protein binding;GO:0032691//negative regulation of interleukin-1 beta production;GO:0042981//regulation of apoptotic process;GO:0097340//inhibition of cysteine-type endopeptidase activity	--
ENSG00000255508	0.503	0.845	1.003	1.08	0.623	0.909	52.88	89.25	77.8	84	55.32	69.46	TUT1	novel protein	-	-	-	-	GO:0043231//intracellular membrane-bounded organelle	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0016779//nucleotidyltransferase activity	-	--
ENSG00000255524	0	0	0.128	0	0	0	0	0	1	0	0	0	NPIPB8	nuclear pore complex interacting protein family member B8 [Source:HGNC Symbol;Acc:HGNC:37490]	-	-	-	-	GO:0005654//nucleoplasm	-	-	--
ENSG00000255526	0.255	0	0.131	0.416	0	0	2.49	0	1.19	4.3	0	0	NEDD8-MDP1	NEDD8-MDP1 readthrough [Source:HGNC Symbol;Acc:HGNC:39551]	-	-	-	-	-	GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0016791//phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation	--
ENSG00000255529	96.994	74.572	93.437	94.926	50.267	53.806	1561	1322.69	1021.93	824	1015	1084.98	POLR2M	RNA polymerase II subunit M [Source:HGNC Symbol;Acc:HGNC:14862]	Genetic Information Processing	Transcription	ko03020//RNA polymerase	K21987	"GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005665//RNA polymerase II, core complex;GO:0016591//RNA polymerase II, holoenzyme;GO:0043025//neuronal cell body"	GO:0003899//DNA-directed 5'-3' RNA polymerase activity	GO:0032774//RNA biosynthetic process;GO:0035556//intracellular signal transduction;GO:0051685//maintenance of ER location	--
ENSG00000255552	0	0	0	0	0	0	0	0	0	0	0	0	LY6G6E	lymphocyte antigen 6 family member G6E [Source:HGNC Symbol;Acc:HGNC:13934]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000255561	0.48	0.831	0.653	0.778	1.405	0.573	27.62	41	26.74	33	65	23.61	FDXACB1	ferredoxin-fold anticodon binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25110]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0070042//rRNA (uridine-N3-)-methyltransferase activity	GO:0070475//rRNA base methylation	--
ENSG00000255582	0	0	0	0	0	0	0	0	0	0	0	0	OR10G2	olfactory receptor family 10 subfamily G member 2 [Source:HGNC Symbol;Acc:HGNC:8170]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255587	0.011	0	0	0	0	0	1	0	0	0	0	0	RAB44	"RAB44, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21068]"	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035577//azurophil granule membrane;GO:0035579//specific granule membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005525//GTP binding	-	--
ENSG00000255639	4.041	3.434	4.113	4.984	4.541	5.606	272.84	237.51	186.91	254.01	263.96	276.77	NDUFA9	novel protein	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953;K03953	-	GO:0003824//catalytic activity;GO:0030246//carbohydrate binding	GO:0034645//cellular macromolecule biosynthetic process	--
ENSG00000255641	0	0	0	0	0.057	0	0	0	0	0	1	0	KLRC3	novel protein	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04650//Natural killer cell mediated cytotoxicity;ko04612//Antigen processing and presentation	K24233;K24233	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000255663	0.452	0.251	0.414	0	0.663	0.837	6.84	3.82	4.62	0	8.47	9.21	RBM7	"novel transcript, RBM7-REXO2 readthrough"	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome"	--
ENSG00000255690	0.717	0.916	0.63	0.681	0.677	0.506	74	95	48	52	59	38	TRIL	TLR4 interactor with leucine rich repeats [Source:HGNC Symbol;Acc:HGNC:22200]	-	-	-	-	GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0046696//lipopolysaccharide receptor complex	GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding	GO:0002376//immune system process;GO:0002718//regulation of cytokine production involved in immune response;GO:0006954//inflammatory response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0045087//innate immune response	--
ENSG00000255713	0	0	0	0	0	0	0	0	0	0	0	0	OR4D2	olfactory receptor family 4 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8294]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255730	1.01	0.802	0.23	0.394	0.739	0.248	41.05	32.77	6.9	11.86	25.37	7.34	BCKDHA	novel protein	Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko00280//Valine, leucine and isoleucine degradation;ko00640//Propanoate metabolism"	K00166;K00166;K00166	GO:0005759//mitochondrial matrix	"GO:0003863//3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity;GO:0016491//oxidoreductase activity;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"	GO:0009083//branched-chain amino acid catabolic process	--
ENSG00000255804	0	0	0.031	0.031	0	0	0	0	2	2	0	0	OR6J1	olfactory receptor family 6 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:14707]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000255819	0	0	0	0	0	0	0	0	0	0	0	0	KLRC4-KLRK1	KLRC4-KLRK1 readthrough [Source:HGNC Symbol;Acc:HGNC:48357]	Organismal Systems	Immune system	ko04612//Antigen processing and presentation	K24234	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000255823	0.037	0	0	0	0	0	1	0	0	0	0	0	MTRNR2L8	MT-RNR2 like 8 [Source:HGNC Symbol;Acc:HGNC:37165]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000255833	0	0	0	0	0	0	0	0	0	0	0	0	TIFAB	TIFA inhibitor [Source:HGNC Symbol;Acc:HGNC:34024]	-	-	-	-	-	GO:0005515//protein binding	GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007356//thorax and anterior abdomen determination;GO:0021559//trigeminal nerve development;GO:0021650//vestibulocochlear nerve formation;GO:0030432//peristalsis;GO:0031223//auditory behavior;GO:0035112//genitalia morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048634//regulation of muscle organ development;GO:0048806//genitalia development;GO:0048839//inner ear development;GO:0050885//neuromuscular process controlling balance;GO:0071626//mastication;GO:0090102//cochlea development;GO:0090103//cochlea morphogenesis;GO:0097094//craniofacial suture morphogenesis;GO:0098583//learned vocalization behavior;GO:1901078//negative regulation of relaxation of muscle;GO:1905747//negative regulation of saliva secretion;GO:1905748//hard palate morphogenesis	--
ENSG00000255835	0.156	0	0.199	0	0	0.073	5.26	0	4.95	0	0	1.79	PYCR2	novel protein	Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00330//Arginine and proline metabolism	K00286;K00286;K00286	-	GO:0004735//pyrroline-5-carboxylate reductase activity	GO:0006561//proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0055129//L-proline biosynthetic process	--
ENSG00000255837	0	0	0.028	0	0	0.085	0	0	1	0	0	3	TAS2R20	taste 2 receptor member 20 [Source:HGNC Symbol;Acc:HGNC:19109]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000255855	0	0	0	0	0	0	0	0	0	0	0	0	KDM4F	lysine demethylase 4F [Source:HGNC Symbol;Acc:HGNC:52413]	-	-	-	-	GO:0005634//nucleus	GO:0032452//histone demethylase activity;GO:0032454//histone H3-methyl-lysine-9 demethylase activity	GO:0006338//chromatin remodeling;GO:0016577//histone demethylation;GO:0033169//histone H3-K9 demethylation	--
ENSG00000255872	0	0	0	0	0	0	0	0	0	0	0	0	SHB	novel transcript	-	-	-	-	-	-	-	--
ENSG00000255974	0	0	0	0	0.222	0	0	0	0	0	6	0	CYP2A6	cytochrome P450 family 2 subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:2610]	Metabolism;Human Diseases;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Biosynthesis of other secondary metabolites	ko01100//Metabolic pathways;ko05417//Lipid and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00232//Caffeine metabolism	K17683;K17683;K17683;K17683;K17683;K17683;K17683;K17683	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008389//coumarin 7-hydroxylase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006082//organic acid metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process;GO:0009804//coumarin metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042178//xenobiotic catabolic process;GO:0046226//coumarin catabolic process	--
ENSG00000256029	0.04	0.138	0.134	0.167	0.065	0.081	6.4	22.35	15.98	20	8.8	9.54	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000256043	15.345	15.607	15.327	14.498	14.92	13.533	908	921	668	634	742	586	CTSO	cathepsin O [Source:HGNC Symbol;Acc:HGNC:2542]	Cellular Processes;Cellular Processes	Cell growth and death;Transport and catabolism	ko04210//Apoptosis;ko04142//Lysosome	K01374;K01374	GO:0005615//extracellular space;GO:0005764//lysosome	GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process	--
ENSG00000256045	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L10	MT-RNR2 like 10 [Source:HGNC Symbol;Acc:HGNC:37167]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000256053	13.613	9.741	12.495	12.895	11.842	12.302	270.18	209.33	183.33	190	194	185	COA8	cytochrome c oxidase assembly factor 8 [Source:HGNC Symbol;Acc:HGNC:20492]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0099617//matrix side of mitochondrial inner membrane	-	GO:0000302//response to reactive oxygen species;GO:0006915//apoptotic process;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0050821//protein stabilization;GO:0097193//intrinsic apoptotic signaling pathway;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1904960//positive regulation of cytochrome-c oxidase activity	--
ENSG00000256060	3.175	2.901	3.846	2.887	2.531	3.83	49	45	43.83	33	33	43	TRAPPC2B	trafficking protein particle complex subunit 2B [Source:HGNC Symbol;Acc:HGNC:10710]	-	-	-	-	GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030008//TRAPP complex;GO:0043231//intracellular membrane-bounded organelle;GO:0048471//perinuclear region of cytoplasm;GO:1990071//TRAPPII protein complex;GO:1990072//TRAPPIII protein complex	GO:0001222//transcription corepressor binding;GO:0005515//protein binding;GO:0140416//transcription regulator inhibitor activity	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006901//vesicle coating;GO:0010628//positive regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0048208//COPII vesicle coating;GO:0099022//vesicle tethering	--
ENSG00000256061	1.078	2.253	1.413	0.995	1.446	1	36	74	38	28	43	25	DNAAF4	dynein axonemal assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21493]	-	-	-	-	GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0097730//non-motile cilium;GO:0120293//dynein axonemal particle	GO:0005515//protein binding;GO:0030331//estrogen receptor binding	GO:0001764//neuron migration;GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0007368//determination of left/right symmetry;GO:0007399//nervous system development;GO:0007507//heart development;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0061136//regulation of proteasomal protein catabolic process	--
ENSG00000256087	4.139	4.42	3.721	2.827	1.735	1.814	256	213	140	125	141	85	ZNF432	zinc finger protein 432 [Source:HGNC Symbol;Acc:HGNC:20810]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000256100	0	0.011	0	0	0	0	0	0.13	0	0	0	0	COX8A	novel transcript	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273;K02273	GO:0005743//mitochondrial inner membrane;GO:0005751//mitochondrial respiratory chain complex IV;GO:0016020//membrane	-	"GO:0006119//oxidative phosphorylation;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen"	--
ENSG00000256162	0	0	0	0	0	0	0	0	0	0	0	0	SMLR1	small leucine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:44670]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000256188	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R30	taste 2 receptor member 30 [Source:HGNC Symbol;Acc:HGNC:19112]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000256206	0.109	0.054	0	0	0.136	0.239	2.75	1.38	0	0	2.9	4.4	PSMA1	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02725;K02725;K02725;K02725;K02725;K02725;K02725;K02725	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019773//proteasome core complex, alpha-subunit complex"	-	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000256222	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L3	MT-RNR2 like 3 [Source:HGNC Symbol;Acc:HGNC:37157]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000256223	3.856	4.467	3.181	2.182	3.694	2.772	236	228	155	107	174	114	ZNF10	zinc finger protein 10 [Source:HGNC Symbol;Acc:HGNC:12879]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000256229	0	0.062	0	0	0.015	0.068	0	5	0	0	1	4	ZNF486	zinc finger protein 486 [Source:HGNC Symbol;Acc:HGNC:20807]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0070062//extracellular exosome	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008150//biological_process"	zf-C2H2
ENSG00000256235	4.945	5.266	4.935	5.563	4.765	6.099	156	167	115	130	127	140	SMIM3	small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000256269	11.569	12.786	15.889	16.071	14.039	14.288	355	401	363	373	369	310	HMBS	hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K01749;K01749	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004418//hydroxymethylbilane synthase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process;GO:0018160//peptidyl-pyrromethane cofactor linkage;GO:0033014//tetrapyrrole biosynthetic process	--
ENSG00000256294	3.229	2.937	2.609	3.324	2.451	2.157	249	194	141	155	151	108	ZNF225	zinc finger protein 225 [Source:HGNC Symbol;Acc:HGNC:13018]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000256349	0	0	0	0	0.838	0	0	0	0	0	52.1	0	BBS1	novel protein	-	-	-	-	GO:0034464//BBSome	-	GO:1905515//non-motile cilium assembly	--
ENSG00000256394	0	0	0	0	0	0	0	0	0	0	0	0	ASIC5	acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537]	Organismal Systems	Sensory system	ko04750//Inflammatory mediator regulation of TRP channels	K04832	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005272//sodium channel activity;GO:0015252//proton channel activity;GO:0015280//ligand-gated sodium channel activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0035725//sodium ion transmembrane transport;GO:1902600//proton transmembrane transport	--
ENSG00000256407	0.114	0.062	0.033	0.117	0.039	0	5.76	3.08	1.19	4.33	1.62	0	CYB5RL	novel transcript	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	-	GO:0016491//oxidoreductase activity	-	--
ENSG00000256436	0	0	0	0.064	0	0	0	0	0	1	0	0	TAS2R31	taste 2 receptor member 31 [Source:HGNC Symbol;Acc:HGNC:19113]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000256453	0.073	0	0.134	0	0.211	0	2.41	0	3.28	0	5.89	0	DND1	DND microRNA-mediated repression inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:23799]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding	GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0048255//mRNA stabilization;GO:0060965//negative regulation of gene silencing by miRNA;GO:0061158//3'-UTR-mediated mRNA destabilization	--
ENSG00000256463	0	0	0	0	0	0	0	0	0	0	0	0	SALL3	spalt like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10527]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000256500	1.607	1.996	1.275	0	0	0	83.51	104.22	48.94	0	0	0	KLC1	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05132//Salmonella infection	K10407;K10407;K10407;K10407;K10407;K10407;K10407	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0016020//membrane	GO:0005515//protein binding	GO:0097193//intrinsic apoptotic signaling pathway	--
ENSG00000256514	2.339	2.336	2.076	2.808	4.276	1.359	34.49	34.62	22.61	30.67	53.28	14.58	POLD4	novel protein	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Replication and repair;Replication and repair;Replication and repair;Replication and repair;Replication and repair	ko03420//Nucleotide excision repair;ko03440//Homologous recombination;ko03030//DNA replication;ko03410//Base excision repair;ko03430//Mismatch repair	K03505;K03505;K03505;K03505;K03505	-	-	GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication	--
ENSG00000256525	1.759	2.019	1.553	1.908	2.03	1.881	74	76	50	48	68	48	POLG2	"DNA polymerase gamma 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9180]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005760//gamma DNA polymerase complex;GO:0042645//mitochondrial nucleoid	GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0030337//DNA polymerase processivity factor activity;GO:0042802//identical protein binding;GO:0070182//DNA polymerase binding	GO:0001701//in utero embryonic development;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006264//mitochondrial DNA replication;GO:0006281//DNA repair;GO:0022904//respiratory electron transport chain;GO:0032042//mitochondrial DNA metabolic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0070584//mitochondrion morphogenesis;GO:0071897//DNA biosynthetic process;GO:1900264//positive regulation of DNA-directed DNA polymerase activity	--
ENSG00000256537	6.797	6.166	6.415	4.926	5.561	5.317	680	620	474	365	470	387	SMIM10L1	small integral membrane protein 10 like 1 [Source:HGNC Symbol;Acc:HGNC:49847]	-	-	-	-	-	-	-	--
ENSG00000256566	0	0.407	0.359	0	0.275	0	0	6.98	4.52	0	3.96	0	ZNF343	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000256574	0.071	0	0	0	0	0	3	0	0	0	0	0	OR13A1	olfactory receptor family 13 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:14772]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000256591	1.871	2.637	1.726	3.344	1.453	3.855	22.51	31.89	15.34	29.8	14.77	35.51	SDHAF2	novel transcript	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	-	"GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0018293//protein-FAD linkage"	--
ENSG00000256618	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L1	MT-RNR2 like 1 [Source:HGNC Symbol;Acc:HGNC:37155]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000256646	2.838	4.415	3.236	2.394	1.066	3.762	143.06	223.84	120.45	91.25	49.76	139.39	PSMA2	novel PSMA2 and C7orf25 readthrough	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02726;K02726;K02726;K02726;K02726;K02726;K02726;K02726	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex"	-	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000256660	0	0	0	0	0	0	0	0	0	0	0	0	CLEC12B	C-type lectin domain family 12 member B [Source:HGNC Symbol;Acc:HGNC:31966]	-	-	-	-	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0032991//protein-containing complex	GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0030246//carbohydrate binding;GO:0030545//signaling receptor regulator activity;GO:0030547//signaling receptor inhibitor activity	GO:0002769//natural killer cell inhibitory signaling pathway;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0097325//melanocyte proliferation;GO:1904893//negative regulation of receptor signaling pathway via STAT;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000256671	0.088	0.071	0.023	0.1	0.054	0.061	3.72	2.35	0.56	3.21	1.49	1.94	LIMS4	LIM zinc finger domain containing 4 [Source:HGNC Symbol;Acc:HGNC:39941]	-	-	-	-	GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000256683	2.587	2.831	2.301	2.191	2.423	1.885	121	139	83	75	100	67	ZNF350	zinc finger protein 350 [Source:HGNC Symbol;Acc:HGNC:16656]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0017053//transcription repressor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000256713	0.035	0	0	0	0	0.127	1	0	0	0	0	2	PGA5	pepsinogen A5 [Source:HGNC Symbol;Acc:HGNC:8887]	Organismal Systems	Digestive system	ko04974//Protein digestion and absorption	K06002	GO:0005576//extracellular region;GO:0070062//extracellular exosome;GO:0097486//multivesicular body lumen	GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis;GO:0007586//digestion	--
ENSG00000256762	0	0.216	0	0	0	0	0	2	0	0	0	0	STH	saitohin [Source:HGNC Symbol;Acc:HGNC:18839]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	"GO:0048026//positive regulation of mRNA splicing, via spliceosome"	--
ENSG00000256771	3.443	3.172	2.328	1.399	2.895	2.662	196	154.22	107	65	117	117	ZNF253	zinc finger protein 253 [Source:HGNC Symbol;Acc:HGNC:13497]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000256797	0	0	0	0	0	0	0	0	0	0	0	0	KLRF2	killer cell lectin like receptor F2 [Source:HGNC Symbol;Acc:HGNC:37646]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0042803//protein homodimerization activity	GO:0001819//positive regulation of cytokine production;GO:0043320//natural killer cell degranulation	--
ENSG00000256806	1.687	2.126	1.713	2.391	1.93	2.589	60	76	45	63	58	67	C17orf100	chromosome 17 open reading frame 100 [Source:HGNC Symbol;Acc:HGNC:34494]	-	-	-	-	-	-	-	--
ENSG00000256812	0	0	0	0	0	0	0	0	0	0	0	0	CAPNS2	calpain small subunit 2 [Source:HGNC Symbol;Acc:HGNC:16371]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000256825	0	0	0	0	0	0	0	0	0	0	0	0	ZNF268	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000256861	0	0	0	0	0	0	0	0	0	0	0	0	VPS33A	novel protein	Human Diseases	Infectious disease: bacterial	ko05132//Salmonella infection	K20182	GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane	-	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000256870	0.216	0.239	0.472	0.292	0.228	0.314	18	20	29	18	16	19	SLC5A8	solute carrier family 5 member 8 [Source:HGNC Symbol;Acc:HGNC:19119]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome	GO:0005343//organic acid:sodium symporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015552//propionate transmembrane transporter activity;GO:0015636//short-chain fatty acid transmembrane transporter activity;GO:0022803//passive transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0140161//monocarboxylate:sodium symporter activity	GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0006915//apoptotic process;GO:0015718//monocarboxylic acid transport;GO:0015730//propanoate transport;GO:0015913//short-chain fatty acid import;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0035873//lactate transmembrane transport;GO:0055085//transmembrane transport;GO:1903825//organic acid transmembrane transport	--
ENSG00000256892	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L7	MT-RNR2 like 7 [Source:HGNC Symbol;Acc:HGNC:37164]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000256950	0	0	0	0	0	0	0	0	0	0	0	0	PSMD9	novel transcript	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K06693;K06693;K06693;K06693;K06693;K06693;K06693;K06693	-	-	GO:0070682//proteasome regulatory particle assembly	--
ENSG00000256966	0.087	0	0	0.262	0	0	1.3	0	0	2.89	0	0	--	novel transcript	-	-	-	-	GO:0005742//mitochondrial outer membrane translocase complex	-	-	--
ENSG00000256977	0.007	0.071	0.023	0	0.054	0	0.24	2.35	0.56	0	1.49	0	LIMS3	LIM zinc finger domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30047]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030054//cell junction;GO:0110165//cellular anatomical entity	GO:0046872//metal ion binding	-	--
ENSG00000256980	0	0.141	0	0	0	0	0	2	0	0	0	0	KHDC1L	KH domain containing 1 like [Source:HGNC Symbol;Acc:HGNC:37274]	-	-	-	-	GO:0005737//cytoplasm	GO:0003723//RNA binding	GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000257008	0	0	0	0	0	0	0	0	0	0	0	0	GPR142	G protein-coupled receptor 142 [Source:HGNC Symbol;Acc:HGNC:20088]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0004930//G protein-coupled receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000257017	0	0	0	0	0.048	0.053	0	0	0	0	1	1	HP	haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031838//haptoglobin-hemoglobin complex;GO:0035580//specific granule lumen;GO:0070062//extracellular exosome;GO:0071682//endocytic vesicle lumen;GO:0072562//blood microparticle;GO:1904724//tertiary granule lumen	GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0016209//antioxidant activity;GO:0030492//hemoglobin binding	GO:0002252//immune effector process;GO:0002376//immune system process;GO:0002526//acute inflammatory response;GO:0006508//proteolysis;GO:0006952//defense response;GO:0006953//acute-phase response;GO:0006955//immune response;GO:0010942//positive regulation of cell death;GO:0031638//zymogen activation;GO:0042542//response to hydrogen peroxide;GO:0042742//defense response to bacterium;GO:0051354//negative regulation of oxidoreductase activity;GO:0098869//cellular oxidant detoxification;GO:2000296//negative regulation of hydrogen peroxide catabolic process	--
ENSG00000257046	0	0	0	0	0	0	0	0	0	0	0	0	SLCO1B3-SLCO1B7	SLCO1B3-SLCO1B7 readthrough [Source:HGNC Symbol;Acc:HGNC:54403]	Organismal Systems	Digestive system	ko04976//Bile secretion	K05043	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0055085//transmembrane transport	--
ENSG00000257057	0.143	0.143	0.194	0	0	0	2	2	2	0	0	0	C11orf97	chromosome 11 open reading frame 97 [Source:HGNC Symbol;Acc:HGNC:49544]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097546//ciliary base	-	-	--
ENSG00000257062	0	0	0	0	0	0	0	0	0	0	0	0	SLCO1B7	novel transcript	Organismal Systems	Digestive system	ko04976//Bile secretion	K05043	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity	GO:0015721//bile acid and bile salt transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport	--
ENSG00000257065	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000257093	6.497	6.379	7.252	6.198	6.714	7.247	985	972	812	696	860	782	DENND11	DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472]	-	-	-	-	GO:0005737//cytoplasm	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000257103	36.076	41.595	43.307	33.095	30.173	55.526	2509	2352	1686	1509	1720	1837	LSM14A	LSM14A mRNA processing body assembly factor [Source:HGNC Symbol;Acc:HGNC:24489]	-	-	-	-	GO:0000932//P-body;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0010494//cytoplasmic stress granule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0072686//mitotic spindle;GO:1990124//messenger ribonucleoprotein complex	GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	GO:0006417//regulation of translation;GO:0017148//negative regulation of translation;GO:0033962//P-body assembly;GO:0034063//stress granule assembly;GO:0039529//RIG-I signaling pathway;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0090307//mitotic spindle assembly	--
ENSG00000257108	0.047	0	0	0	0	0	2	0	0	0	0	0	NHLRC4	NHL repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:26700]	-	-	-	-	-	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0070936//protein K48-linked ubiquitination	--
ENSG00000257115	0	0	0	0	0	0	0	0	0	0	0	0	OR11H12	olfactory receptor family 11 subfamily H member 12 [Source:HGNC Symbol;Acc:HGNC:30738]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000257138	0	0	0	0	0	0	0	0	0	0	0	0	TAS2R38	taste 2 receptor member 38 [Source:HGNC Symbol;Acc:HGNC:9584]	Organismal Systems	Sensory system	ko04742//Taste transduction	K08474	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0033038//bitter taste receptor activity	GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050896//response to stimulus;GO:0050909//sensory perception of taste	--
ENSG00000257184	0	0	0	0	0	0	0	0	0	0	0	0	HOXA9	HOXA10-HOXA9 readthrough	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K21950	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000257207	0.026	0	0	0	0	0	1.76	0	0	0	0	0	LIMS1	novel transcript	-	-	-	-	-	-	-	--
ENSG00000257218	10.854	10.494	11.373	9.283	9.42	10.113	938.78	877.3	670.73	578.48	674.5	614.57	GATC	glutamyl-tRNA amidotransferase subunit C [Source:HGNC Symbol;Acc:HGNC:25068]	Metabolism;Genetic Information Processing	Global and overview maps;Translation	ko01100//Metabolic pathways;ko00970//Aminoacyl-tRNA biosynthesis	K02435;K02435	GO:0005739//mitochondrion;GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"	GO:0006412//translation;GO:0006450//regulation of translational fidelity;GO:0032543//mitochondrial translation;GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation	--
ENSG00000257315	4.444	3.488	3.344	2.417	2.001	2.327	1150.55	907.62	639.38	463.53	437.72	438.39	ZBED6	zinc finger BED-type containing 6 [Source:HGNC Symbol;Acc:HGNC:33273]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0034451//centriolar satellite	"GO:0000976//transcription cis-regulatory region binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001835//blastocyst hatching;GO:0003309//type B pancreatic cell differentiation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045787//positive regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051148//negative regulation of muscle cell differentiation;GO:0060548//negative regulation of cell death;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus"	zf-BED
ENSG00000257335	0	0	0	0.02	0	0	0	0	0	2	0	0	MGAM	maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K12047;K12047;K12047;K12047	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular exosome;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	"GO:0003824//catalytic activity;GO:0004339//glucan 1,4-alpha-glucosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0005515//protein binding;GO:0016160//amylase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding;GO:0032450//maltose alpha-glucosidase activity;GO:0090599//alpha-glucosidase activity"	GO:0000025//maltose catabolic process;GO:0005975//carbohydrate metabolic process;GO:0005983//starch catabolic process;GO:0008152//metabolic process;GO:1901027//dextrin catabolic process	--
ENSG00000257341	0	0	0.334	0.44	0	0	0	0	3.47	4.58	0	0	CRIP1	novel protein	-	-	-	-	-	GO:0008270//zinc ion binding	GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010468//regulation of gene expression	--
ENSG00000257355	0	0.066	0	0	0	0	0	0.75	0	0	0	0	ZNF878	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000257365	8.916	9.313	10.156	10.411	9.354	10.78	501.36	526.39	421.78	433.66	444.4	441.07	FNTB	"farnesyltransferase, CAAX box, beta [Source:HGNC Symbol;Acc:HGNC:3785]"	Metabolism	Metabolism of terpenoids and polyketides	ko00900//Terpenoid backbone biosynthesis	K05954	GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005965//protein farnesyltransferase complex	GO:0003824//catalytic activity;GO:0004659//prenyltransferase activity;GO:0004660//protein farnesyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008318//protein prenyltransferase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0018342//protein prenylation;GO:0018343//protein farnesylation	--
ENSG00000257390	0.112	0.188	0	0.186	0	0.134	4.19	7.08	0	5.16	0	3.65	DNAJC14	novel protein	-	-	-	-	GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding	-	--
ENSG00000257411	0	0	0	0	0	1.524	0	0	0	0	0	11.25	PA2G4	novel protein	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases	Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: overview;Signal transduction;Drug resistance: antineoplastic	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko05205//Proteoglycans in cancer;ko05206//MicroRNAs in cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance	K05084;K05084;K05084;K05084;K05084;K05084;K05084	-	-	-	--
ENSG00000257446	0	0.034	0.074	0	0.032	0	0	1.25	2	0	1	0	ZNF878	zinc finger protein 878 [Source:HGNC Symbol;Acc:HGNC:37246]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000257520	0	0	0	0	0	0	0	0	0	0	0	0	NKX2-1	novel protein	-	-	-	-	-	-	-	--
ENSG00000257524	3.274	3.609	3.286	3.624	2.759	3.54	209.79	212.01	117.3	148.7	118.93	119.22	ST6GALNAC6	novel protein	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03376;K03376	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008373//sialyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006486//protein glycosylation;GO:0097503//sialylation	--
ENSG00000257529	0.701	2.228	2.651	2.395	0.404	2.207	8.2	26.16	22.91	20.82	4.05	18.78	RPL36A-HNRNPH2	RPL36A-HNRNPH2 readthrough [Source:HGNC Symbol;Acc:HGNC:48349]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02929;K02929	GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005886//plasma membrane	GO:0003735//structural constituent of ribosome	GO:0006412//translation	--
ENSG00000257591	0.472	0.138	0	0	0.302	0.8	14.55	2	0	0	9	16.42	ZNF625	zinc finger protein 625 [Source:HGNC Symbol;Acc:HGNC:30571]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000257594	1.388	1.255	1.382	1.406	1.625	1.922	155.04	140.87	114	116.29	153.39	156.17	GALNT4	polypeptide N-acetylgalactosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:4126]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular exosome	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding	GO:0006486//protein glycosylation;GO:0016266//O-glycan processing;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine	--
ENSG00000257704	11.378	11.548	12.293	11.481	10.95	10.188	198	202	158	148	161	129	INAFM1	InaF motif containing 1 [Source:HGNC Symbol;Acc:HGNC:27406]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000257727	50.009	50.67	58.673	62.712	48.003	49.836	1330.47	1368.08	1065.13	1133.02	1109.06	916.19	CNPY2	canopy FGF signaling regulator 2 [Source:HGNC Symbol;Acc:HGNC:13529]	-	-	-	-	GO:0005783//endoplasmic reticulum	GO:0005515//protein binding	GO:0010629//negative regulation of gene expression;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:1905599//positive regulation of low-density lipoprotein receptor activity	--
ENSG00000257743	0.25	0.182	0.281	0.295	0.318	0.31	41	30	34	32	44	37	MGAM2	maltase-glucoamylase 2 (putative) [Source:HGNC Symbol;Acc:HGNC:28101]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Digestive system;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04973//Carbohydrate digestion and absorption;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K12047;K12047;K12047;K12047	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003824//catalytic activity;GO:0004339//glucan 1,4-alpha-glucosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0030246//carbohydrate binding"	GO:0005975//carbohydrate metabolic process;GO:0008152//metabolic process	--
ENSG00000257767	2.54	2.485	9.639	6.776	5.074	7.851	41.31	40.62	115.77	81.62	69.71	92.89	ALDH2	novel protein	Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Carbohydrate metabolism;Amino acid metabolism;Lipid metabolism;Amino acid metabolism;Amino acid metabolism;Carbohydrate metabolism;Lipid metabolism;Amino acid metabolism;Metabolism of other amino acids;Carbohydrate metabolism;Amino acid metabolism;Metabolism of cofactors and vitamins;Metabolism of terpenoids and polyketides	"ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko00010//Glycolysis / Gluconeogenesis;ko00310//Lysine degradation;ko00561//Glycerolipid metabolism;ko00330//Arginine and proline metabolism;ko00280//Valine, leucine and isoleucine degradation;ko00620//Pyruvate metabolism;ko00071//Fatty acid degradation;ko00380//Tryptophan metabolism;ko00410//beta-Alanine metabolism;ko00053//Ascorbate and aldarate metabolism;ko00340//Histidine metabolism;ko00770//Pantothenate and CoA biosynthesis;ko00981//Insect hormone biosynthesis"	K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128;K00128	-	GO:0004029//aldehyde dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity	-	--
ENSG00000257921	0.466	0.283	0.342	0	0	0.162	14.72	4	11.76	0	0	5.48	EEF1AKMT3	novel protein	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0018023//peptidyl-lysine trimethylation;GO:0032259//methylation	--
ENSG00000257923	24.936	25.628	23.647	19.892	22.213	20.392	3079	2960	2075	1737	2292	1819	CUX1	cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557]	-	-	-	-	GO:0000139//Golgi membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007275//multicellular organism development;GO:0050775//positive regulation of dendrite morphogenesis"	CUT
ENSG00000257949	8.266	8.766	8.243	9.556	7.734	7.468	167	178	123	143	132	109	TEN1	TEN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:37242]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:1990879//CST complex"	GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0010521//telomerase inhibitor activity;GO:0042162//telomeric DNA binding	GO:0016233//telomere capping;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0051974//negative regulation of telomerase activity	--
ENSG00000257950	0.288	0.201	0.261	0.354	0.261	0.263	35.29	24.73	23.63	32.08	26.96	23.42	P2RX5-TAX1BP3	P2RX5-TAX1BP3 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49191]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway	K05219;K05219	-	-	-	--
ENSG00000257987	0	0	0	0	0	0	0	0	0	0	0	0	TEX49	testis expressed 49 [Source:HGNC Symbol;Acc:HGNC:48628]	-	-	-	-	-	-	-	--
ENSG00000258052	0	0	0	0	0	0	0	0	0	0	0	0	RAB3IP	novel protein	-	-	-	-	GO:0070319//Golgi to plasma membrane transport vesicle	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0006887//exocytosis;GO:0050790//regulation of catalytic activity	--
ENSG00000258064	0	0	0	0	0	0	0	0	0	0	0	0	THAP2	novel protein	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding	-	THAP
ENSG00000258083	0	0	0	0	0	0	0	0	0	0	0	0	OR9A4	olfactory receptor family 9 subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:15095]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000258102	0.061	0.182	0.266	0.166	0	0.519	1.04	3.1	3.33	2.09	0	6.41	MAP1LC3B2	microtubule associated protein 1 light chain 3 beta 2 [Source:HGNC Symbol;Acc:HGNC:34390]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Cellular Processes;Environmental Information Processing;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Immune system;Transport and catabolism;Signal transduction;Transport and catabolism;Cell growth and death	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05131//Shigellosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko04140//Autophagy - animal;ko04371//Apelin signaling pathway;ko04137//Mitophagy - animal;ko04216//Ferroptosis	K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435;K10435	GO:0000421//autophagosome membrane;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding	GO:0000045//autophagosome assembly;GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0006995//cellular response to nitrogen starvation;GO:0016236//macroautophagy;GO:0097352//autophagosome maturation	--
ENSG00000258223	0	0	0	0	0	0	0	0	0	0	0	0	PRSS58	serine protease 58 [Source:HGNC Symbol;Acc:HGNC:39125]	-	-	-	-	GO:0005576//extracellular region;GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000258227	0	0	0	0	0	0	0	0	0	0	0	0	CLEC5A	C-type lectin domain containing 5A [Source:HGNC Symbol;Acc:HGNC:2054]	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane	GO:0001618//virus receptor activity;GO:0030246//carbohydrate binding	GO:0001819//positive regulation of cytokine production;GO:0002076//osteoblast development;GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0030099//myeloid cell differentiation;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045087//innate immune response;GO:0046718//viral entry into host cell	--
ENSG00000258289	16.964	10.42	9.18	9.867	8.367	9.728	732.96	597.9	441.08	340	445.78	430	CHURC1	churchill domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20099]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0007275//multicellular organism development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000258311	9.487	9.004	11.26	18.134	16.338	15.487	665.48	634.84	583.37	942.3	968.29	742.54	BLOC1S1	novel protein	-	-	-	-	GO:0005758//mitochondrial intermembrane space;GO:0005765//lysosomal membrane;GO:0031083//BLOC-1 complex	-	GO:0051641//cellular localization	--
ENSG00000258315	15.893	17.017	17.936	20.673	18.484	15.291	269	292.66	222.3	270	258	190	C17orf49	chromosome 17 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28737]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016589//NURF complex;GO:0071339//MLL1 complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0006325//chromatin organization	--
ENSG00000258366	3.107	3.382	4.368	6.67	3.846	4.691	233.84	296	194.82	282	293.29	226	RTEL1	regulator of telomere elongation helicase 1 [Source:HGNC Symbol;Acc:HGNC:15888]	-	-	-	-	"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm"	"GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0070182//DNA polymerase binding"	GO:0000723//telomere maintenance;GO:0000732//strand displacement;GO:0006139//nucleobase-containing compound metabolic process;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0031297//replication fork processing;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0043247//telomere maintenance in response to DNA damage;GO:0045910//negative regulation of DNA recombination;GO:0090657//telomeric loop disassembly;GO:1902990//mitotic telomere maintenance via semi-conservative replication;GO:1904355//positive regulation of telomere capping;GO:1904358//positive regulation of telomere maintenance via telomere lengthening;GO:1904430//negative regulation of t-circle formation;GO:1904506//negative regulation of telomere maintenance in response to DNA damage;GO:1904535//positive regulation of telomeric loop disassembly	--
ENSG00000258388	0.582	0.612	0.931	0.242	1.015	2.091	20.39	28.44	16.59	5.89	44.39	38.45	PPT2-EGFL8	PPT2-EGFL8 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48343]	Metabolism;Cellular Processes;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko01212//Fatty acid metabolism;ko00062//Fatty acid elongation	K01074;K01074;K01074;K01074	GO:0005764//lysosome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016787//hydrolase activity;GO:0016790//thiolester hydrolase activity	GO:0098734//macromolecule depalmitoylation	--
ENSG00000258405	0	0	0	0	0	0	0	0	0	0	0	0	ZNF578	zinc finger protein 578 [Source:HGNC Symbol;Acc:HGNC:26449]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000258417	74.497	99.414	58.783	38.44	49.679	27.061	3728.61	5001.31	2172.93	1425.14	2100.68	985.47	OC90	novel protein	-	-	-	-	GO:0005576//extracellular region	GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0046872//metal ion binding	GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0050482//arachidonic acid secretion	--
ENSG00000258429	2.849	3.087	2.627	2.185	2.88	2.911	168.95	184	115.04	96	144.31	125.61	PDF	"peptide deformylase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30012]"	-	-	-	-	GO:0005739//mitochondrion	GO:0016787//hydrolase activity;GO:0042586//peptide deformylase activity;GO:0046872//metal ion binding	GO:0006412//translation;GO:0008284//positive regulation of cell population proliferation;GO:0018206//peptidyl-methionine modification;GO:0031365//N-terminal protein amino acid modification;GO:0043686//co-translational protein modification	--
ENSG00000258436	0	0	0	0	0	0	0	0	0	0	0	0	RNASE12	ribonuclease A family member 12 (inactive) [Source:HGNC Symbol;Acc:HGNC:24211]	-	-	-	-	GO:0005576//extracellular region	GO:0003676//nucleic acid binding	-	--
ENSG00000258453	0	0	0	0	0	0	0	0	0	0	0	0	OR11H2	olfactory receptor family 11 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:14716]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000258461	0.229	0.169	0.345	0.083	0.142	0.102	18.45	11.18	20.51	4.06	9.63	5.96	GANC	novel transcript	Metabolism;Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00500//Starch and sucrose metabolism;ko00052//Galactose metabolism	K12317;K12317;K12317	-	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity;GO:0090599//alpha-glucosidase activity"	GO:0006491//N-glycan processing	--
ENSG00000258465	6.177	8.048	9.576	7.556	7.987	7.387	331.68	430.97	379.5	300.58	362.38	288.42	PEX19	novel protein	-	-	-	-	GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0016020//membrane	-	GO:0007031//peroxisome organization	--
ENSG00000258466	0	0	0	0	0	0	0	0	0	0	0	0	RDH11	novel protein	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00830//Retinol metabolism	K11152;K11152	-	GO:0016491//oxidoreductase activity	-	--
ENSG00000258472	0.091	0.08	0.077	0.063	0.201	0.156	3.96	3.48	2.48	2.01	7.37	4.93	RSKR	novel protein	-	-	-	-	-	-	GO:0051301//cell division;GO:0051988//regulation of attachment of spindle microtubules to kinetochore	--
ENSG00000258484	0	0	0	0	0	0	0	0	0	0	0	0	SPESP1	sperm equatorial segment protein 1 [Source:HGNC Symbol;Acc:HGNC:15570]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0043231//intracellular membrane-bounded organelle	-	GO:0007340//acrosome reaction;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0009566//fertilization;GO:0035036//sperm-egg recognition	--
ENSG00000258529	0.101	0	0.59	0	0	0.538	6.14	0	10.42	0	0	19.98	ALG9	novel protein	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00510//N-Glycan biosynthesis;ko00513//Various types of N-glycan biosynthesis	K03846;K03846;K03846	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000030//mannosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0052918//dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0052926//dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0070042//rRNA (uridine-N3-)-methyltransferase activity"	GO:0006486//protein glycosylation;GO:0070475//rRNA base methylation;GO:0097502//mannosylation	--
ENSG00000258539	0.317	0.288	0.547	0.385	0.413	0.273	22.53	20.57	28.67	20.26	24.79	14.11	Eef1akmt2	"novel transcript, METTL10-FAM53B readthrough"	-	-	-	-	GO:0005737//cytoplasm	GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity	GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation	--
ENSG00000258555	0	0	0	0	0	0.362	0	0	0	0	0	33.87	SPECC1L-ADORA2A	SPECC1L-ADORA2A readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49185]	-	-	-	-	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005921//gap junction;GO:0030054//cell junction	-	GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000258588	0.15	0.624	0	0	0	0	10.58	44.11	0	0	0	0	TRIM6-TRIM34	TRIM6-TRIM34 readthrough [Source:HGNC Symbol;Acc:HGNC:33440]	-	-	-	-	-	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0046872//metal ion binding	-	--
ENSG00000258597	0	0.052	0	0	0	0	0	1	0	0	0	0	SERPINA2	serpin family A member 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:8985]	-	-	-	-	GO:0005615//extracellular space	GO:0004867//serine-type endopeptidase inhibitor activity	GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000258643	4.358	3.292	3.677	2.421	4.842	1.948	119.04	88.74	73.93	49.76	109.52	43.21	BCL2L2-PABPN1	BCL2L2-PABPN1 readthrough [Source:HGNC Symbol;Acc:HGNC:42959]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05164//Influenza A;ko03015//mRNA surveillance pathway	K14396;K14396	GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0097136//Bcl-2 family protein complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0097718//disordered domain specific binding	GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042981//regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway	--
ENSG00000258644	0.838	0.552	0	0.223	0.671	0.756	12.22	8.18	0	3.19	8.34	7.48	SYNJ2BP-COX16	SYNJ2BP-COX16 readthrough [Source:HGNC Symbol;Acc:HGNC:48350]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0005515//protein binding	-	--
ENSG00000258653	0.223	0.315	0.302	0.527	0.156	0.317	17.1	24.23	17.09	29.9	10.1	17.68	PTGR2	novel protein	-	-	-	-	-	"GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0036132//13-prostaglandin reductase activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity"	GO:0006693//prostaglandin metabolic process	--
ENSG00000258659	0.385	0.038	0.512	0.426	0.398	0.376	18.33	1.8	18	15	16	13	TRIM34	tripartite motif containing 34 [Source:HGNC Symbol;Acc:HGNC:10063]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000209//protein polyubiquitination;GO:0010468//regulation of gene expression;GO:0010508//positive regulation of autophagy;GO:0016567//protein ubiquitination;GO:0032880//regulation of protein localization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0046596//regulation of viral entry into host cell;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051607//defense response to virus	--
ENSG00000258674	0.114	0.065	0	0.216	0.286	0.22	2.59	1.48	0	3.65	5.51	3.66	YJEFN3	novel protein	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	GO:0008137//NADH dehydrogenase (ubiquinone) activity	GO:0022900//electron transport chain	--
ENSG00000258677	1.614	2.88	2.304	1.662	2.399	1.246	25.98	46.59	27.39	19.81	32.62	14.59	UBE2W	"novel  protein, UBE2W-STAU2 readthrough"	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10688	-	-	-	--
ENSG00000258691	0	0	0	0	0.145	0	0	0	0	0	1.52	0	ITCH	novel protein	-	-	-	-	-	-	-	--
ENSG00000258713	0	0	0	0	0	0	0	0	0	0	0	0	C20orf141	chromosome 20 open reading frame 141 [Source:HGNC Symbol;Acc:HGNC:16134]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000258724	0	0	0.07	0	0	0	0	0	1.87	0	0	0	PINX1	PIN2 (TERF1) interacting telomerase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:30046]	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003677//DNA binding	-	HMG
ENSG00000258728	0.29	0.578	1.112	1.835	1.142	1.277	26.98	53.95	52.54	56.64	65.48	47.6	IL11RA	novel protein (GALT-IL11RA readthrough)	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signal transduction	ko04060//Cytokine-cytokine receptor interaction;ko04640//Hematopoietic cell lineage;ko04630//JAK-STAT signaling pathway	K05056;K05056;K05056	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008108//UDP-glucose:hexose-1-phosphate uridylyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	GO:0005975//carbohydrate metabolic process;GO:0006012//galactose metabolic process;GO:0033499//galactose catabolic process via UDP-galactose	--
ENSG00000258790	3.425	3.982	4.233	4.493	3.868	2.608	274.02	320.2	250.13	266.28	261.41	151.79	PRORP	novel transcript	-	-	-	-	-	-	-	--
ENSG00000258806	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000258817	0	0	0	0	0	0	0	0	0	0	0	0	OR4C13	olfactory receptor family 4 subfamily C member 13 [Source:HGNC Symbol;Acc:HGNC:15169]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000258818	19.607	16.452	14.953	12.746	13.77	19.299	649.23	556.87	391.13	320.96	376.25	424.71	RNASE4	ribonuclease A family member 4 [Source:HGNC Symbol;Acc:HGNC:10047]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004522//ribonuclease A activity;GO:0004540//ribonuclease activity;GO:0016787//hydrolase activity	"GO:0006379//mRNA cleavage;GO:0016070//RNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000258830	0.129	0.308	0	0.27	0.704	0.274	5.64	13.53	0	8.73	25.99	8.72	R3HDM2	novel protein	-	-	-	-	-	GO:0003676//nucleic acid binding	-	--
ENSG00000258839	1.258	1.423	1.37	1.639	1.322	0.938	57	67.2	49	58	55	32	MC1R	melanocortin 1 receptor [Source:HGNC Symbol;Acc:HGNC:6929]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04916//Melanogenesis	K04199;K04199	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity;GO:0005515//protein binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0042562//hormone binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007275//multicellular organism development;GO:0009650//UV protection;GO:0010739//positive regulation of protein kinase A signaling;GO:0019222//regulation of metabolic process;GO:0019233//sensory perception of pain;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035556//intracellular signal transduction;GO:0042438//melanin biosynthetic process;GO:0043473//pigmentation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051897//positive regulation of protein kinase B signaling;GO:0060259//regulation of feeding behavior;GO:0070914//UV-damage excision repair;GO:0090037//positive regulation of protein kinase C signaling;GO:2000253//positive regulation of feeding behavior"	--
ENSG00000258864	1.413	0.143	1.159	0.689	0	0.361	20.34	2.07	12.32	7.35	0	3.78	APC	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: viral;Cell motility;Cancer: overview;Signal transduction;Cancer: specific types;Endocrine and metabolic disease;Signal transduction;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Cancer: specific types;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko04810//Regulation of actin cytoskeleton;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko05225//Hepatocellular carcinoma;ko04934//Cushing syndrome;ko04390//Hippo signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko04550//Signaling pathways regulating pluripotency of stem cells;ko05210//Colorectal cancer;ko05217//Basal cell carcinoma;ko05213//Endometrial cancer	K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085;K02085	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005881//cytoplasmic microtubule;GO:0016342//catenin complex;GO:0030877//beta-catenin destruction complex	GO:0008013//beta-catenin binding;GO:0008017//microtubule binding;GO:0045295//gamma-catenin binding	GO:0000281//mitotic cytokinesis;GO:0001708//cell fate specification;GO:0006974//cellular response to DNA damage stimulus;GO:0007026//negative regulation of microtubule depolymerization;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0008285//negative regulation of cell population proliferation;GO:0016477//cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0045595//regulation of cell differentiation;GO:0045732//positive regulation of protein catabolic process;GO:0051726//regulation of cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000258873	0	0	0	0	0	0	0	0	0	0	0	0	DUXA	double homeobox A [Source:HGNC Symbol;Acc:HGNC:32179]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	Homeobox
ENSG00000258881	0.025	0	0.017	0	0.058	0	2.12	0	1.07	0	4.22	0	TEX261	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0097020//COPII receptor activity	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006897//endocytosis	--
ENSG00000258890	3.268	3.53	3.224	2.704	2.906	2.4	153	167	106	79	101	91	CEP95	centrosomal protein 95 [Source:HGNC Symbol;Acc:HGNC:25141]	-	-	-	-	GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	-	--
ENSG00000258947	32.226	39.238	30.768	17.783	17.686	17.208	1142.77	1398.39	807.46	469.06	532.13	446.06	TUBB3	tubulin beta 3 class III [Source:HGNC Symbol;Acc:HGNC:20772]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0030426//growth cone;GO:0042995//cell projection;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005525//GTP binding;GO:1990890//netrin receptor binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0007411//axon guidance;GO:0038007//netrin-activated signaling pathway;GO:1990791//dorsal root ganglion development	--
ENSG00000258984	0	0	0.229	0	0	0.077	0	0	3.34	0	0	1.11	UBE2F-SCLY	UBE2F-SCLY readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48339]	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10687	-	-	-	--
ENSG00000258986	0.151	0.014	0	0.019	0.04	0.026	7	1	0	1	2	1	TMEM179	transmembrane protein 179 [Source:HGNC Symbol;Acc:HGNC:20137]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000258989	0	0	0	0	0	0.228	0	0	0	0	0	2.68	PRKCH	novel protein	Organismal Systems;Organismal Systems	Circulatory system;Sensory system	ko04270//Vascular smooth muscle contraction;ko04750//Inflammatory mediator regulation of TRP channels	K18051;K18051	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000258992	0	0	0	0	0	0	0	0	0	0	0	0	TSPY1	testis specific protein Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:12381]	-	-	-	-	GO:0000785//chromatin;GO:0005575//cellular_component;GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0003674//molecular_function;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding	GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0007548//sex differentiation;GO:0030154//cell differentiation	--
ENSG00000259024	3.266	4.068	3.441	2.957	3.016	2.642	191.89	169.44	136.14	128.72	149.74	112.95	TVP23C-CDRT4	TVP23C-CDRT4 readthrough [Source:HGNC Symbol;Acc:HGNC:42961]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000259030	0.101	0.039	0.255	0.026	0.022	0.156	10.29	4.13	13.44	3.01	1.07	8.29	FPGT-TNNI3K	FPGT-TNNI3K readthrough [Source:HGNC Symbol;Acc:HGNC:42952]	-	-	-	-	-	"GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups"	GO:0006468//protein phosphorylation	--
ENSG00000259040	0	0	0	0	0	0	0	0	0	0	0	0	BLOC1S5-TXNDC5	BLOC1S5-TXNDC5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:42001]	-	-	-	-	GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex	-	-	--
ENSG00000259060	0	0	0	0	0	0	0	0	0	0	0	0	RNASE12	novel protein	-	-	-	-	-	GO:0003676//nucleic acid binding	-	--
ENSG00000259066	0	0	0	0	0.214	0	0	0	0	0	2.08	0	UBR7	novel protein	-	-	-	-	GO:0016020//membrane	GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000259075	0.42	0.187	0	0.395	0.186	0.145	42.96	21.24	0	20.71	17.73	4.83	POC1B-GALNT4	POC1B-GALNT4 readthrough [Source:HGNC Symbol;Acc:HGNC:42957]	Metabolism;Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00514//Other types of O-glycan biosynthesis;ko00512//Mucin type O-glycan biosynthesis	K00710;K00710;K00710	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0030246//carbohydrate binding	GO:0006486//protein glycosylation;GO:0006493//protein O-linked glycosylation	--
ENSG00000259112	5.257	3.318	2.093	1.14	3.432	1.96	71.53	45.38	21.03	11.49	39.07	19.4	NDUFC2-KCTD14	NDUFC2-KCTD14 readthrough [Source:HGNC Symbol;Acc:HGNC:42956]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968;K03968	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070469//respirasome	-	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone"	--
ENSG00000259120	0.111	0.111	0.151	0.114	0.198	0.536	2	2	2	2	3	7	SMIM6	small integral membrane protein 6 [Source:HGNC Symbol;Acc:HGNC:40032]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000259132	0	0	0	0	2.019	0	0	0	0	0	29.54	0	HAUS4	novel protein	-	-	-	-	GO:0070652//HAUS complex	GO:0051011//microtubule minus-end binding	GO:0007098//centrosome cycle;GO:0051225//spindle assembly	--
ENSG00000259164	0	0	0	0	0	0	0	0	0	0	0	0	CIPC	novel protein	-	-	-	-	-	-	"GO:0042754//negative regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000259171	0.561	2.041	2.428	0.421	2.634	0	17.43	63.74	55.72	9.7	69.14	0	ANG	"novel protein, ANG-RNASE4 readthrough"	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K16631	-	-	-	--
ENSG00000259207	0.333	0.576	0.253	0.095	0.115	0.112	40.99	65	23	7	12	10	ITGB3	integrin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6156]	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases	Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: viral;Cell motility;Signal transduction;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Cardiovascular disease;Cardiovascular disease;Development and regeneration;Immune system;Endocrine system;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04613//Neutrophil extracellular trap formation;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0031092//platelet alpha granule membrane;GO:0031258//lamellipodium membrane;GO:0031527//filopodium membrane;GO:0031528//microvillus membrane;GO:0032587//ruffle membrane;GO:0032991//protein-containing complex;GO:0034683//integrin alphav-beta3 complex;GO:0035866//alphav-beta3 integrin-PKCalpha complex;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0035868//alphav-beta3 integrin-HMGB1 complex;GO:0042470//melanosome;GO:0042995//cell projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0070062//extracellular exosome;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0098978//glutamatergic synapse	GO:0001618//virus receptor activity;GO:0001968//fibronectin binding;GO:0002020//protease binding;GO:0003756//protein disulfide isomerase activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0017134//fibroblast growth factor binding;GO:0019899//enzyme binding;GO:0019960//C-X3-C chemokine binding;GO:0031994//insulin-like growth factor I binding;GO:0038132//neuregulin binding;GO:0042802//identical protein binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0050839//cell adhesion molecule binding;GO:0050840//extracellular matrix binding	GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007596//blood coagulation;GO:0010595//positive regulation of endothelial cell migration;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0014909//smooth muscle cell migration;GO:0016477//cell migration;GO:0030168//platelet activation;GO:0030198//extracellular matrix organization;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0032147//activation of protein kinase activity;GO:0032369//negative regulation of lipid transport;GO:0032880//regulation of protein localization;GO:0033627//cell adhesion mediated by integrin;GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0035295//tube development;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0042060//wound healing;GO:0043277//apoptotic cell clearance;GO:0045124//regulation of bone resorption;GO:0046718//viral entry into host cell;GO:0048333//mesodermal cell differentiation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050748//negative regulation of lipoprotein metabolic process;GO:0050919//negative chemotaxis;GO:0051611//regulation of serotonin uptake;GO:0060055//angiogenesis involved in wound healing;GO:0070527//platelet aggregation;GO:0099149//regulation of postsynaptic neurotransmitter receptor internalization;GO:1905598//negative regulation of low-density lipoprotein receptor activity	--
ENSG00000259224	0.122	0	0.082	0.123	0.036	0	4	0	2	3	1	0	SLC35G6	solute carrier family 35 member G6 [Source:HGNC Symbol;Acc:HGNC:31351]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000259261	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4OR15-8	immunoglobulin heavy variable 4/OR15-8 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5658]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000259288	0	0	0	0	0	0	0	0	0	0	0	0	BUB1B-PAK6	BUB1B-PAK6 readthrough [Source:HGNC Symbol;Acc:HGNC:52276]	Human Diseases;Cellular Processes	Infectious disease: viral;Cell growth and death	ko05166//Human T-cell leukemia virus 1 infection;ko04110//Cell cycle	K06637;K06637	GO:0043229//intracellular organelle	-	GO:0007094//mitotic spindle assembly checkpoint signaling	--
ENSG00000259303	0	0	0	0	0	0	0	0	0	0	0	0	IGHV2OR16-5	immunoglobulin heavy variable 2/OR16-5 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5579]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000259305	0.847	0.447	0.244	0.274	0.53	0.722	16.55	7.79	4.69	5.29	11.68	8.16	ZHX1-C8orf76	ZHX1-C8orf76 readthrough [Source:HGNC Symbol;Acc:HGNC:42975]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000259316	0.408	0	0	0.032	0.019	0.712	7.78	0	0	0.45	0.31	9.89	PCLAF	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm	-	GO:0006974//cellular response to DNA damage stimulus;GO:0051726//regulation of cell cycle	--
ENSG00000259330	6.855	7.217	6.908	7.124	7.095	7.559	430	455	320	331	376	345	INAFM2	InaF motif containing 2 [Source:HGNC Symbol;Acc:HGNC:35165]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000259332	5.131	5.082	6.311	5.87	4.616	7.639	76.75	76.42	65.96	63.34	59.09	80.05	ST20-MTHFS	ST20-MTHFS readthrough [Source:HGNC Symbol;Acc:HGNC:44655]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00670//One carbon pool by folate	K01934;K01934	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0030272//5-formyltetrahydrofolate cyclo-ligase activity;GO:0046872//metal ion binding	-	--
ENSG00000259371	0.175	0.208	0	0.2	0.204	0	3.08	3.69	0	2.61	3.04	0	DCAF11	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0080008//Cul4-RING E3 ubiquitin ligase complex	GO:0005515//protein binding	GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process	--
ENSG00000259384	0	0	0	0	0.069	0	0	0	0	0	1	0	GH1	growth hormone 1 [Source:HGNC Symbol;Acc:HGNC:4261]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031904//endosome lumen;GO:0031982//vesicle;GO:0062023//collagen-containing extracellular matrix;GO:0070195//growth hormone receptor complex	GO:0005131//growth hormone receptor binding;GO:0005148//prolactin receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0046872//metal ion binding	GO:0007165//signal transduction;GO:0007259//receptor signaling pathway via JAK-STAT;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0010828//positive regulation of glucose transmembrane transport;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0031667//response to nutrient levels;GO:0032355//response to estradiol;GO:0040018//positive regulation of multicellular organism growth;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043406//positive regulation of MAP kinase activity;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060396//growth hormone receptor signaling pathway;GO:0070977//bone maturation	--
ENSG00000259399	0.266	0.321	1.279	1.667	0	0.751	5.06	6.15	17.98	23.51	0	10.41	TGIF2-RAB5IF	TGIF2-RAB5IF readthrough [Source:HGNC Symbol;Acc:HGNC:44664]	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003677//DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006996//organelle organization;GO:0097250//mitochondrial respirasome assembly"	--
ENSG00000259417	0.091	0.049	0.133	0.132	0.075	0.106	13	7	14	14	9	11	CTXND1	cortexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:50507]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000259431	13.006	12.951	13.941	15.08	15.796	16.571	440.12	475.85	361.57	362.28	462.97	406.02	THTPA	thiamine triphosphatase [Source:HGNC Symbol;Acc:HGNC:18987]	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00730//Thiamine metabolism	K05307;K05307	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0050333//thiamin-triphosphatase activity	GO:0006091//generation of precursor metabolites and energy;GO:0006772//thiamine metabolic process;GO:0016311//dephosphorylation;GO:0042357//thiamine diphosphate metabolic process	--
ENSG00000259490	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5633]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000259494	10.345	8.256	8.685	9.164	7.585	10.71	211.7	168.24	129.45	139	131.07	156.92	MRPL46	mitochondrial ribosomal protein L46 [Source:HGNC Symbol;Acc:HGNC:1192]	-	-	-	-	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome;GO:0030054//cell junction	GO:0003674//molecular_function;GO:0003735//structural constituent of ribosome	GO:0008150//biological_process;GO:0032543//mitochondrial translation	--
ENSG00000259522	0.272	0.328	0.417	0.178	0	0	24.53	29.78	27.79	11.9	0	0	TM9SF1	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0072657//protein localization to membrane	--
ENSG00000259529	0.778	0.449	0.983	0.279	0.596	1.211	89.92	52.2	83.92	23.86	58.18	101.91	RNF31	novel transcript	Human Diseases;Organismal Systems;Cellular Processes	Infectious disease: bacterial;Immune system;Cell growth and death	ko05131//Shigellosis;ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis	K11974;K11974;K11974	GO:0071797//LUBAC complex	GO:0004842//ubiquitin-protein transferase activity;GO:0016740//transferase activity;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:1990450//linear polyubiquitin binding	GO:0097039//protein linear polyubiquitination	--
ENSG00000259571	0	0	0	0	0	0	0	0	0	0	0	0	BLID	"BH3-like motif containing, cell death inducer [Source:HGNC Symbol;Acc:HGNC:33495]"	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003674//molecular_function	GO:0006915//apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	--
ENSG00000259680	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-17	immunoglobulin heavy variable 3/OR16-17 (non-functional) [Source:HGNC Symbol;Acc:HGNC:55105]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000259753	0.125	0	0	0	0	0	7.2	0	0	0	0	0	ITGB3	novel protein	Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases	Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune system;Infectious disease: viral;Cell motility;Signal transduction;Transport and catabolism;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Immune system;Cardiovascular disease;Cardiovascular disease;Development and regeneration;Immune system;Endocrine system;Cardiovascular disease;Signaling molecules and interaction;Cardiovascular disease	ko05168//Herpes simplex virus 1 infection;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko04613//Neutrophil extracellular trap formation;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04145//Phagosome;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko05410//Hypertrophic cardiomyopathy;ko04512//ECM-receptor interaction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493;K06493	GO:0005925//focal adhesion;GO:0008305//integrin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0001968//fibronectin binding;GO:0005178//integrin binding	GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0030198//extracellular matrix organization;GO:0033627//cell adhesion mediated by integrin;GO:0070527//platelet aggregation	--
ENSG00000259784	0	0	0	0.549	0	0	0	0	0	5.03	0	0	AMDHD2	novel protein	Metabolism;Metabolism	Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko00520//Amino sugar and nucleotide sugar metabolism	K01443;K01443	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008448//N-acetylglucosamine-6-phosphate deacetylase activity	GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0071704//organic substance metabolic process	--
ENSG00000259803	0	0	0	0.04	0	0	0	0	0	1	0	0	SLC22A31	solute carrier family 22 member 31 [Source:HGNC Symbol;Acc:HGNC:27091]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0022857//transmembrane transporter activity	GO:0006811//ion transport;GO:0055085//transmembrane transport	--
ENSG00000259823	0	0	0	0	0	0	0	0	0	0	0	0	LYPD8	LY6/PLAUR domain containing 8 [Source:HGNC Symbol;Acc:HGNC:44208]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	-	GO:0050829//defense response to Gram-negative bacterium	--
ENSG00000259900	0	0	0	0	0	0	0	0	0	0	0	0	TMED6	novel protein	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle	-	GO:0006886//intracellular protein transport;GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030//Golgi organization	--
ENSG00000259916	0	0.03	0.021	0	0	0.049	0	2	1	0	0	1	AQP7P3	novel member of the aquaporin (AQP) gene family	Organismal Systems;Organismal Systems	Endocrine system;Endocrine system	ko03320//PPAR signaling pathway;ko04923//Regulation of lipolysis in adipocytes	K08771;K08771	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0110165//cellular anatomical entity	GO:0015204//urea transmembrane transporter activity;GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0015267//channel activity	GO:0006833//water transport;GO:0015793//glycerol transport;GO:0055085//transmembrane transport;GO:0071918//urea transmembrane transport	--
ENSG00000259956	13.08	14.142	14.058	12.019	13.022	13.292	1797.13	1952.96	1426.49	1223.19	1511.53	1328.74	RBM15B	RNA binding motif protein 15B [Source:HGNC Symbol;Acc:HGNC:24303]	-	-	-	-	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0036396//RNA N6-methyladenosine methyltransferase complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0001510//RNA methylation;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0009048//dosage compensation by inactivation of X chromosome"	--
ENSG00000260001	0.15	0.112	0.051	0	0.089	0.026	8	6	2	0	4	1	TGFBR3L	transforming growth factor beta receptor 3 like [Source:HGNC Symbol;Acc:HGNC:44152]	-	-	-	-	GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005539//glycosaminoglycan binding;GO:0050431//transforming growth factor beta binding	GO:0001837//epithelial to mesenchymal transition;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016477//cell migration;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway	--
ENSG00000260007	0.131	0.06	0.403	0.659	0.269	0.114	8.02	3.66	2.13	3.07	13.91	5.07	CLN6	novel protein	-	-	-	-	-	-	-	--
ENSG00000260027	0	0	0	0	0.042	0	0	0	0	0	1	0	HOXB7	homeobox B7 [Source:HGNC Symbol;Acc:HGNC:5118]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016604//nuclear body	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0030099//myeloid cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048568//embryonic organ development;GO:0048704//embryonic skeletal system morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis"	Homeobox
ENSG00000260092	0.059	0.186	0	0.044	0.161	0	2.58	8.22	0	1.44	6	0	TMEM231	TMEM231-CHST5 readthrough protein	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035869//ciliary transition zone;GO:0042995//cell projection;GO:0060170//ciliary membrane	-	GO:0030030//cell projection organization;GO:0032880//regulation of protein localization;GO:0060271//cilium assembly	--
ENSG00000260097	0.008	0	0	0	0	0	0.51	0	0	0	0	0	SPDYE6	speedy/RINGO cell cycle regulator family member E6 [Source:HGNC Symbol;Acc:HGNC:35465]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0005515//protein binding;GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000260170	0.446	0	0.265	0	0	0.612	9.81	0	4.31	0	0	9.79	SQOR	novel protein	Metabolism;Metabolism	Global and overview maps;Energy metabolism	ko01100//Metabolic pathways;ko00920//Sulfur metabolism	K22470;K22470	GO:0005739//mitochondrion	GO:0016491//oxidoreductase activity;GO:0070224//sulfide:quinone oxidoreductase activity;GO:0071949//FAD binding	"GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase"	--
ENSG00000260220	0.024	0.009	0.039	0.006	0.006	0	5	2	6	1	1	0	CCDC187	coiled-coil domain containing 187 [Source:HGNC Symbol;Acc:HGNC:30942]	-	-	-	-	GO:0005813//centrosome	GO:0008017//microtubule binding	GO:0034453//microtubule anchoring	--
ENSG00000260230	1.945	1.588	1.777	1.413	1.609	1.952	329	270	222	177	230	234	FRRS1L	ferric chelate reductase 1 like [Source:HGNC Symbol;Acc:HGNC:1362]	-	-	-	-	GO:0005575//cellular_component;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse	GO:0003674//molecular_function	GO:0099072//regulation of postsynaptic membrane neurotransmitter receptor levels;GO:1900449//regulation of glutamate receptor signaling pathway	--
ENSG00000260234	0	0	0	0	0	0	0	0	0	0	0	0	CLRN1	CLRN1 and FAM188B2 readthrough transcript	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007605//sensory perception of sound;GO:0050957//equilibrioception	--
ENSG00000260238	5.797	4.322	4.364	5.213	5.488	8.177	120.11	87.14	65.14	80.32	96.85	122.63	PMF1-BGLAP	PMF1-BGLAP readthrough [Source:HGNC Symbol;Acc:HGNC:42953]	-	-	-	-	"GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000818//nuclear MIS12/MIND complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle"	-	GO:0007049//cell cycle;GO:0051301//cell division	--
ENSG00000260272	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D24	novel protein	-	-	-	-	GO:0005737//cytoplasm	-	GO:0031175//neuron projection development	--
ENSG00000260286	0	0	0	0	0	0	0	0	0	0	0	0	ARMH2	armadillo like helical domain containing 2 [Source:HGNC Symbol;Acc:HGNC:49394]	-	-	-	-	-	-	-	--
ENSG00000260287	0	0	0.416	0.217	0.148	0.094	0	0	13.17	6.89	5.37	2.93	TBC1D3G	TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0090630//activation of GTPase activity	--
ENSG00000260314	0.019	0.009	0.05	0	0.055	0.013	2	1	4	0	5	1	MRC1	mannose receptor C-type 1 [Source:HGNC Symbol;Acc:HGNC:7228]	Human Diseases;Cellular Processes	Infectious disease: bacterial;Transport and catabolism	ko05152//Tuberculosis;ko04145//Phagosome	K06560;K06560	GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001618//virus receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0038024//cargo receptor activity	GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0046718//viral entry into host cell;GO:0071222//cellular response to lipopolysaccharide;GO:0071346//cellular response to interferon-gamma;GO:0071353//cellular response to interleukin-4	--
ENSG00000260325	0	0.087	0	0	0	0	0	1	0	0	0	0	HSPB9	heat shock protein family B (small) member 9 [Source:HGNC Symbol;Acc:HGNC:30589]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	GO:0005515//protein binding	-	--
ENSG00000260342	0.497	0.123	0.346	0.372	0.294	1.058	7.88	1.96	4.05	4.37	3.94	12.2	ARL6IP1	novel protein	-	-	-	-	GO:0005784//Sec61 translocon complex;GO:0005840//ribosome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0006613//cotranslational protein targeting to membrane	--
ENSG00000260371	0	0	0.193	0	0	0	0	0	1.67	0	0	0	COG8	novel protein	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex	-	GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport	--
ENSG00000260428	1.351	2.125	1.653	2.177	1.445	1.198	31	49	28	37	28	20	SCX	scleraxis bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:32322]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0070888//E-box binding"	"GO:0001707//mesoderm formation;GO:0001894//tissue homeostasis;GO:0001958//endochondral ossification;GO:0002062//chondrocyte differentiation;GO:0003179//heart valve morphogenesis;GO:0003188//heart valve formation;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0008284//positive regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030199//collagen fibril organization;GO:0030509//BMP signaling pathway;GO:0032502//developmental process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0035914//skeletal muscle cell differentiation;GO:0035989//tendon development;GO:0035990//tendon cell differentiation;GO:0035992//tendon formation;GO:0035993//deltoid tuberosity development;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048706//embryonic skeletal system development;GO:0060008//Sertoli cell differentiation;GO:0060325//face morphogenesis;GO:0061035//regulation of cartilage development;GO:0061036//positive regulation of cartilage development;GO:0061056//sclerotome development;GO:0071260//cellular response to mechanical stimulus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0071773//cellular response to BMP stimulus;GO:2000543//positive regulation of gastrulation"	bHLH
ENSG00000260456	2.409	1.288	1.42	2.235	1.816	1.765	48.7	26	21.02	33	30.58	26	C16orf95	chromosome 16 open reading frame 95 [Source:HGNC Symbol;Acc:HGNC:40033]	-	-	-	-	-	-	-	--
ENSG00000260458	0	0	0	0	0	0	0	0	0	0	0	0	KCNJ18	potassium inwardly rectifying channel subfamily J member 18 [Source:HGNC Symbol;Acc:HGNC:39080]	Organismal Systems;Organismal Systems	Endocrine system;Nervous system	ko04921//Oxytocin signaling pathway;ko04725//Cholinergic synapse	K05005;K05005	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005242//inward rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005515//protein binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:1990573//potassium ion import across plasma membrane	--
ENSG00000260537	3.588	3.219	0.87	1.587	1.699	2.709	58.04	54.72	7.53	21.14	23.69	35.26	DDX19B	"novel protein, DDX19B and DDX19A readthrough"	Genetic Information Processing;Genetic Information Processing	Translation;Translation	ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K18655;K18655	-	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000260596	0	0	0	0	0.067	0	0	0	0	0	2	0	DUX4	double homeobox 4 [Source:HGNC Symbol;Acc:HGNC:50800]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031965//nuclear membrane	"GO:0000976//transcription cis-regulatory region binding;GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell population proliferation;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070317//negative regulation of G0 to G1 transition	Homeobox
ENSG00000260643	2.39	2.748	2.241	0.924	2.291	2.116	75.96	75.2	45.9	25.58	62.15	49.97	GCSH	novel protein	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K02437;K02437;K02437;K02437	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005960//glycine cleavage complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:1990204//oxidoreductase complex	-	GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0044281//small molecule metabolic process	--
ENSG00000260691	0.05	0.051	0.039	0.14	0.076	0.018	3.87	4	2.27	3	5	1	ANKRD20A1	ankyrin repeat domain 20 family member A1 [Source:HGNC Symbol;Acc:HGNC:23665]	-	-	-	-	GO:0005886//plasma membrane	GO:0005515//protein binding	-	--
ENSG00000260729	0.123	0.115	0.126	0.119	0.078	0.07	11.14	10.46	8.43	7.97	5.97	4.65	HEXA	novel protein	Metabolism;Cellular Processes;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Transport and catabolism;Carbohydrate metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00520//Amino sugar and nucleotide sugar metabolism;ko00513//Various types of N-glycan biosynthesis;ko00531//Glycosaminoglycan degradation;ko00511//Other glycan degradation;ko00604//Glycosphingolipid biosynthesis - ganglio series;ko00603//Glycosphingolipid biosynthesis - globo and isoglobo series	K12373;K12373;K12373;K12373;K12373;K12373;K12373;K12373	GO:0005764//lysosome	"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0016787//hydrolase activity;GO:0102148//N-acetyl-beta-D-galactosaminidase activity"	GO:0005975//carbohydrate metabolic process;GO:1901135//carbohydrate derivative metabolic process	--
ENSG00000260734	0	0	0	0	0	0	0	0	0	0	0	0	TLE7	TLE family member 7 [Source:HGNC Symbol;Acc:HGNC:53648]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction;Signal transduction	ko04310//Wnt signaling pathway;ko04330//Notch signaling pathway;ko04013//MAPK signaling pathway - fly	K04497;K04497;K04497	GO:0005634//nucleus;GO:0005667//transcription regulator complex	GO:0003714//transcription corepressor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway"	--
ENSG00000260802	0.073	0.01	0	0	0.025	0	7	1	0	0	2	0	SERTM2	serine rich and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:48576]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000260811	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000260836	0.263	0	0.09	0.091	0.293	0	10.96	0	2.78	2.81	10.32	0	CPEB1	novel protein	Cellular Processes;Organismal Systems;Organismal Systems	Cell growth and death;Endocrine system;Development and regeneration	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation;ko04320//Dorso-ventral axis formation	K02602;K02602;K02602	GO:0005737//cytoplasm;GO:0005840//ribosome	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0003735//structural constituent of ribosome;GO:0045182//translation regulator activity;GO:0046872//metal ion binding	GO:0006397//mRNA processing;GO:0006412//translation;GO:0006417//regulation of translation	--
ENSG00000260851	0	0	0	0	0	0	0	0	0	0	0	0	TK2	novel protein	Metabolism;Metabolism;Metabolism	Global and overview maps;Xenobiotics biodegradation and metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko00983//Drug metabolism - other enzymes;ko00240//Pyrimidine metabolism	K00857;K00857;K00857	GO:0005737//cytoplasm	GO:0019136//deoxynucleoside kinase activity	GO:0009157//deoxyribonucleoside monophosphate biosynthetic process	--
ENSG00000260861	0	0	0	0	0	0	0	0	0	0	0	0	SIRPB1	"novel protein, SIRPB1-SIRPD readthrough"	Organismal Systems	Development and regeneration	ko04380//Osteoclast differentiation	K06551	-	-	-	--
ENSG00000260903	0.013	0.006	0	0	0	0	2	1	0	0	0	0	XKR7	XK related 7 [Source:HGNC Symbol;Acc:HGNC:23062]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902742//apoptotic process involved in development	--
ENSG00000260914	8.84	11.738	9.767	12.792	9.231	9.653	235.44	314.21	192.11	252.36	207.7	187.05	VPS4A	novel protein	Cellular Processes;Cellular Processes	Transport and catabolism;Cell growth and death	ko04144//Endocytosis;ko04217//Necroptosis	K12196;K12196	GO:0010008//endosome membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0007033//vacuole organization;GO:0007049//cell cycle;GO:0016197//endosomal transport;GO:0051301//cell division	--
ENSG00000260916	41.953	32.41	31.447	22.51	25.785	31.564	3033.6	2343.2	1631.08	1200.98	1477.49	1587.44	CCPG1	cell cycle progression 1 [Source:HGNC Symbol;Acc:HGNC:24227]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007049//cell cycle;GO:0008284//positive regulation of cell population proliferation;GO:0045787//positive regulation of cell cycle;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2001106//regulation of Rho guanyl-nucleotide exchange factor activity	--
ENSG00000261052	13.296	12.645	15.658	14.678	14.974	18.813	369.47	349.87	317.48	301.95	339.92	381.31	SULT1A3	sulfotransferase family 1A member 3 [Source:HGNC Symbol;Acc:HGNC:11455]	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K01014	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004062//aryl sulfotransferase activity;GO:0005515//protein binding;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity;GO:0043199//sulfate binding;GO:0047685//amine sulfotransferase activity	GO:0006068//ethanol catabolic process;GO:0006584//catecholamine metabolic process;GO:0006629//lipid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0007212//dopamine receptor signaling pathway;GO:0008202//steroid metabolic process;GO:0009812//flavonoid metabolic process;GO:0042420//dopamine catabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0051923//sulfation;GO:0070371//ERK1 and ERK2 cascade;GO:0097720//calcineurin-mediated signaling;GO:0098989//NMDA selective glutamate receptor signaling pathway;GO:1901135//carbohydrate derivative metabolic process;GO:1901215//negative regulation of neuron death;GO:1901564//organonitrogen compound metabolic process;GO:1903351//cellular response to dopamine	--
ENSG00000261115	1.501	1.409	1.339	1.729	1.867	1.773	334	315	220	285	351	287	TMEM178B	transmembrane protein 178B [Source:HGNC Symbol;Acc:HGNC:44112]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261130	0	0	0	0	0.24	0.139	0	0	0	0	2	1	MPV17L	novel protein	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13349	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261147	0.403	0.541	0.213	0.426	0.352	0.356	32.11	43.29	12.55	25.12	23.65	20.6	TTLL13P	novel protein	-	-	-	-	-	-	GO:0006464//cellular protein modification process	--
ENSG00000261150	2.651	2.519	2.426	1.593	2.114	1.875	880	835.05	593	390	593	453	EPPK1	epiplakin 1 [Source:HGNC Symbol;Acc:HGNC:15577]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0030056//hemidesmosome;GO:0042995//cell projection;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0071944//cell periphery;GO:0097356//perinucleolar compartment	GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding;GO:1990254//keratin filament binding	GO:0010839//negative regulation of keratinocyte proliferation;GO:0030336//negative regulation of cell migration;GO:0042060//wound healing;GO:0045104//intermediate filament cytoskeleton organization;GO:0045109//intermediate filament organization;GO:0045110//intermediate filament bundle assembly;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051548//negative regulation of keratinocyte migration;GO:0061045//negative regulation of wound healing;GO:1905041//regulation of epithelium regeneration	--
ENSG00000261210	8.282	7.998	6.416	2.147	2.062	1.909	392	390	192	84	92	70	CLEC19A	C-type lectin domain containing 19A [Source:HGNC Symbol;Acc:HGNC:34522]	-	-	-	-	GO:0005576//extracellular region;GO:0009897//external side of plasma membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding	-	--
ENSG00000261221	4.369	4.614	4.979	5.95	4.565	6.022	341	362	287	344	301	342	ZNF865	zinc finger protein 865 [Source:HGNC Symbol;Acc:HGNC:38705]	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000261236	8.975	11.547	9.948	10.964	12.268	11.223	452	536	370	409	522	357	BOP1	BOP1 ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:15519]	-	-	-	-	"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0070545//PeBoW complex;GO:1990904//ribonucleoprotein complex"	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding	"GO:0000027//ribosomal large subunit assembly;GO:0000448//cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0008283//cell population proliferation;GO:0042254//ribosome biogenesis;GO:0042273//ribosomal large subunit biogenesis;GO:0051726//regulation of cell cycle;GO:1901796//regulation of signal transduction by p53 class mediator"	--
ENSG00000261247	0.123	0.037	0.07	0.024	0.101	0.067	13.23	4.01	5.56	1.89	9.15	5.25	GOLGA8T	golgin A8 family member T [Source:HGNC Symbol;Acc:HGNC:44410]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000261272	0	0	0	0	0	0	0	0	0	0	0	0	MUC22	mucin 22 [Source:HGNC Symbol;Acc:HGNC:39755]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261308	0.625	0.438	0.499	0.664	0.546	0.662	61	43	36	48	45	47	FIGNL2	fidgetin like 2 [Source:HGNC Symbol;Acc:HGNC:13287]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008568//microtubule-severing ATPase activity;GO:0016887//ATP hydrolysis activity	GO:0051013//microtubule severing	--
ENSG00000261341	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261371	0.1	0.134	0.01	0.086	0.39	0.197	3	3	1	9	18	4	PECAM1	platelet and endothelial cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:8823]	Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Cardiovascular disease;Immune system;Infectious disease: parasitic	ko04514//Cell adhesion molecules;ko05418//Fluid shear stress and atherosclerosis;ko04670//Leukocyte transendothelial migration;ko05144//Malaria	K06471;K06471;K06471;K06471	GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030667//secretory granule membrane;GO:0031092//platelet alpha granule membrane;GO:0032991//protein-containing complex;GO:0045121//membrane raft;GO:0070062//extracellular exosome	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity	GO:0001934//positive regulation of protein phosphorylation;GO:0006909//phagocytosis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0008037//cell recognition;GO:0030335//positive regulation of cell migration;GO:0035633//maintenance of blood-brain barrier;GO:0035696//monocyte extravasation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050904//diapedesis;GO:0061028//establishment of endothelial barrier;GO:0070830//bicellular tight junction assembly;GO:0072011//glomerular endothelium development;GO:0072672//neutrophil extravasation;GO:0098609//cell-cell adhesion;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0150107//positive regulation of protein localization to cell-cell junction	--
ENSG00000261408	0	0	0	0	0	0	0	0	0	0	0	0	TEN1-CDK3	TEN1-CDK3 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44420]	-	-	-	-	-	-	-	--
ENSG00000261456	0.071	0.058	0.123	0.159	0.086	0.081	2	1	2	2	2	1	TUBB8	tubulin beta 8 class VIII [Source:HGNC Symbol;Acc:HGNC:20773]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cellular community - eukaryotes	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04145//Phagosome;ko04540//Gap junction	K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375;K07375	GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0070062//extracellular exosome;GO:0072686//mitotic spindle;GO:0072687//meiotic spindle	GO:0000166//nucleotide binding;GO:0003674//molecular_function;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0001556//oocyte maturation;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0007056//spindle assembly involved in female meiosis	--
ENSG00000261459	0	0	0	0.559	0	0	0	0	0	13.01	0	0	ZNF764	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000261509	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3B	TP53 target 3B [Source:HGNC Symbol;Acc:HGNC:37202]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000261582	0	0	0	0	0	0	0	0	0	0	0	0	EIF6	novel transcript	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K03264	"GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030687//preribosome, large subunit precursor"	GO:0003743//translation initiation factor activity;GO:0043022//ribosome binding;GO:0043023//ribosomal large subunit binding	GO:0000054//ribosomal subunit export from nucleus;GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0006412//translation;GO:0006413//translational initiation;GO:0042256//mature ribosome assembly;GO:1902626//assembly of large subunit precursor of preribosome	--
ENSG00000261587	0	0	0	0	0.135	0.445	0	0	0	0	2	6	TMEM249	transmembrane protein 249 [Source:HGNC Symbol;Acc:HGNC:44155]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036128//CatSper complex;GO:0097228//sperm principal piece	-	-	--
ENSG00000261594	0	0	0.067	0	0	0.023	0	0	3	0	0	1	TPBGL	trophoblast glycoprotein like [Source:HGNC Symbol;Acc:HGNC:44159]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0090090//negative regulation of canonical Wnt signaling pathway	--
ENSG00000261609	0.833	0.747	0.825	0.521	0.697	0.715	241	204	137	96	152	142	GAN	gigaxonin [Source:HGNC Symbol;Acc:HGNC:4137]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0007010//cytoskeleton organization;GO:0016567//protein ubiquitination	--
ENSG00000261611	0.23	0.209	0.238	0.514	0.52	0.564	18.51	17.14	14.34	29.97	35.85	33.5	ZNF19	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000261649	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L7	golgin A6 family like 7 [Source:HGNC Symbol;Acc:HGNC:37442]	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network	GO:0005515//protein binding	-	--
ENSG00000261652	1.277	1.16	1.955	0.45	0.46	0.687	23	21	26	6	7	9	C15orf65	chromosome 15 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:44654]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000261667	0	0	0	0	0	0	0	0	0	0	0	0	LY6L	lymphocyte antigen 6 family member L [Source:HGNC Symbol;Acc:HGNC:52284]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	-	-	--
ENSG00000261678	0.012	0	0	0.016	0	0	1	0	0	1	0	0	SCRT1	scratch family transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:15950]	-	-	-	-	GO:0005634//nucleus;GO:0016604//nuclear body	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:2001222//regulation of neuron migration"	zf-C2H2
ENSG00000261701	0	0	0	0	0	0	0	0	0	0	0	0	HPR	haptoglobin-related protein [Source:HGNC Symbol;Acc:HGNC:5156]	Human Diseases	Infectious disease: parasitic	ko05143//African trypanosomiasis	K14477	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0034366//spherical high-density lipoprotein particle;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0004252//serine-type endopeptidase activity;GO:0030492//hemoglobin binding	GO:0002526//acute inflammatory response;GO:0006508//proteolysis;GO:0010942//positive regulation of cell death;GO:0031638//zymogen activation	--
ENSG00000261717	0.11	0.403	0.39	0.41	0.141	0	1.21	4.45	3.17	3.34	1.31	0	TMEM170A	novel TMEM170A-CFDP1 readthrough protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261732	0.262	0.183	0.033	0.258	0.165	0.096	28.93	20.33	2.67	21.13	15.36	7.7	CRAMP1	novel protein	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding	GO:0007389//pattern specification process	--
ENSG00000261739	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA8S	golgin A8 family member S [Source:HGNC Symbol;Acc:HGNC:44409]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000261740	37.435	36.733	42.131	39.949	35.208	42.698	789.43	792.58	668.35	636.59	648.29	661.38	BOLA2-SMG1P6	BOLA2-SMG1P6 readthrough [Source:HGNC Symbol;Acc:HGNC:53563]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K08873	-	"GO:0005515//protein binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0097428//protein maturation by iron-sulfur cluster transfer	--
ENSG00000261787	0	0.02	0.027	0	0.047	0.081	0	1	1	0	2	3	TCF24	transcription factor 24 [Source:HGNC Symbol;Acc:HGNC:32275]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046983//protein dimerization activity"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0032502//developmental process	bHLH
ENSG00000261793	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel transcript, TMEM210 and LRRC26 readthrough"	-	-	-	-	-	-	-	--
ENSG00000261794	0.071	0.058	0.042	0.094	0.053	0.026	7.65	6.3	3.32	7.52	4.85	2.06	GOLGA8H	golgin A8 family member H [Source:HGNC Symbol;Acc:HGNC:37443]	-	-	-	-	GO:0000137//Golgi cis cisterna;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0032580//Golgi cisterna membrane	GO:0005515//protein binding	GO:0007030//Golgi organization	--
ENSG00000261796	5.938	4.226	3.976	4.675	4.101	3.081	599.6	428.88	296.51	349.67	349.86	226.37	ISY1-RAB43	ISY1-RAB43 readthrough [Source:HGNC Symbol;Acc:HGNC:42969]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12870	-	-	GO:0000350//generation of catalytic spliceosome for second transesterification step	--
ENSG00000261832	0.426	0.872	0.421	1.137	0.885	0.638	19.34	37.98	12.06	32.78	31.49	20.2	CLN3	novel protein	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12389	GO:0005654//nucleoplasm;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	-	-	--
ENSG00000261857	0.118	0.098	0.386	1.001	0.585	0	1	1	3	7	5	0	MIA	MIA SH3 domain containing [Source:HGNC Symbol;Acc:HGNC:7076]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005515//protein binding;GO:0008083//growth factor activity	GO:0007165//signal transduction;GO:0030198//extracellular matrix organization	--
ENSG00000261873	0	0	0	0	0	0	0	0	0	0	0	0	SMIM36	small integral membrane protein 36 [Source:HGNC Symbol;Acc:HGNC:53654]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000261884	0	0	0	0	0.212	0	0	0	0	0	2.13	0	PSMB10	novel transcript	Genetic Information Processing	"Folding, sorting and degradation"	ko03050//Proteasome	K02733	"GO:0005634//nucleus;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex"	GO:0004175//endopeptidase activity	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002376//immune system process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000261915	0.766	0.473	0.393	0.312	1.027	0.941	37.3	23.16	15.47	11.25	43.41	33.36	NEURL4	novel protein	-	-	-	-	-	GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000261934	0.018	0.037	0.147	0.076	0.126	0.026	1.75	2	10.75	3	10.54	1	PCDHGA9	"protocadherin gamma subfamily A, 9 [Source:HGNC Symbol;Acc:HGNC:8707]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000261949	0	0	0	0	0	0	0	0	0	0	0	0	GFY	golgi associated olfactory signaling regulator [Source:HGNC Symbol;Acc:HGNC:44663]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030173//integral component of Golgi membrane	-	GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0097499//protein localization to non-motile cilium;GO:1905515//non-motile cilium assembly	--
ENSG00000262085	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000262152	0	0	0	0	0	0	0	0	0	0	0	0	GREP1	glycine rich extracellular protein 1 [Source:HGNC Symbol;Acc:HGNC:27549]	-	-	-	-	-	-	-	--
ENSG00000262165	0	0	0	0	0	0	0	0	0	0	0	0	C17orf114	chromosome 17 open reading frame 114 [Source:HGNC Symbol;Acc:HGNC:55343]	-	-	-	-	-	-	-	--
ENSG00000262179	0	0	0	0	0	0	0	0	0	0	0	0	MYMX	"myomixer, myoblast fusion factor [Source:HGNC Symbol;Acc:HGNC:52391]"	-	-	-	-	GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007517//muscle organ development;GO:0007520//myoblast fusion;GO:0014905//myoblast fusion involved in skeletal muscle regeneration;GO:0043403//skeletal muscle tissue regeneration;GO:0045026//plasma membrane fusion;GO:0060538//skeletal muscle organ development	--
ENSG00000262209	0	0	0	0	0	0	0	0	0	0	0	0	PCDHGB3	"protocadherin gamma subfamily B, 3 [Source:HGNC Symbol;Acc:HGNC:8710]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000262246	6.594	8.198	8.501	9.347	8.618	8.315	394.91	439.81	321	410	450.58	318.69	CORO7	coronin 7 [Source:HGNC Symbol;Acc:HGNC:26161]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	GO:0003779//actin binding;GO:0005515//protein binding;GO:0051015//actin filament binding	GO:0006895//Golgi to endosome transport;GO:0007015//actin filament organization;GO:0015031//protein transport;GO:0030041//actin filament polymerization	--
ENSG00000262302	0	0	0	0	0	0	0	0	0	0	0	0	CLDN7	novel protein	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity	-	--
ENSG00000262304	0	0	0	0	0.096	0	0	0	0	0	7.96	0	SHPK	novel readthrough SHPK-TRPV1 protein	-	-	-	-	-	"GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0050277//sedoheptulokinase activity"	GO:0005975//carbohydrate metabolic process;GO:0016310//phosphorylation	--
ENSG00000262406	0	0	0	0	0.063	0	0	0	0	0	2	0	MMP12	matrix metallopeptidase 12 [Source:HGNC Symbol;Acc:HGNC:7158]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031012//extracellular matrix	GO:0001046//core promoter sequence-specific DNA binding;GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005518//collagen binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006508//proteolysis;GO:0006606//protein import into nucleus;GO:0010628//positive regulation of gene expression;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0032727//positive regulation of interferon-alpha production;GO:0035313//wound healing, spreading of epidermal cells;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048286//lung alveolus development;GO:0050691//regulation of defense response to virus by host;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060309//elastin catabolic process;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060435//bronchiole development;GO:0098586//cellular response to virus;GO:1904645//response to amyloid-beta;GO:1904905//negative regulation of endothelial cell-matrix adhesion via fibronectin"	--
ENSG00000262461	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE9	speedy/RINGO cell cycle regulator family member E9 [Source:HGNC Symbol;Acc:HGNC:45034]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000262481	0.092	0	0	0.451	0	0.243	1.82	0	0	4.81	0	2.06	TMEM256-PLSCR3	TMEM256-PLSCR3 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49186]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000262484	0	0	0	0	0.053	0	0	0	0	0	1	0	CCER2	coiled-coil glutamate rich protein 2 [Source:HGNC Symbol;Acc:HGNC:44662]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000262526	3.591	9.913	0	0	0	9.309	57.8	160.38	0	0	0	109.02	CTDNEP1	novel protein	-	-	-	-	-	GO:0004722//protein serine/threonine phosphatase activity	GO:0006470//protein dephosphorylation	--
ENSG00000262543	0	0	0	0	0	0	0	0	0	0	0	0	SMIM28	small integral membrane protein 28 [Source:HGNC Symbol;Acc:HGNC:53434]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000262560	0.105	0	0	0	0.041	0	5.08	0	0	0	1.69	0	SERINC4	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000262576	0.054	0.036	0.073	0	0.168	0.025	3	3.54	3	0	14.05	1	PCDHGA4	"protocadherin gamma subfamily A, 4 [Source:HGNC Symbol;Acc:HGNC:8702]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000262628	0	0	0	0	0	0	0	0	0	0	0	0	OR1D5	olfactory receptor family 1 subfamily D member 5 [Source:HGNC Symbol;Acc:HGNC:8186]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000262633	4.183	5.941	5.843	3.707	5.929	4.595	77.14	110.11	79.57	50.64	92.36	61.65	GOSR2	novel protein	Genetic Information Processing	"Folding, sorting and degradation"	ko04130//SNARE interactions in vesicular transport	K08496	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005484//SNAP receptor activity	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion	--
ENSG00000262655	0.095	0.104	0.168	0.245	0.328	0.144	10	11	13	19	29	11	SPON1	spondin 1 [Source:HGNC Symbol;Acc:HGNC:11252]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0050693//LBD domain binding	GO:0007155//cell adhesion;GO:0010954//positive regulation of protein processing;GO:0032092//positive regulation of protein binding;GO:1902430//negative regulation of amyloid-beta formation;GO:1902993//positive regulation of amyloid precursor protein catabolic process	--
ENSG00000262660	0	0	0	0	0	0	0	0	0	0	0	0	SLC25A10	novel protein	Organismal Systems	Excretory system	ko04964//Proximal tubule bicarbonate reclamation	K13577	GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005840//ribosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0006839//mitochondrial transport	--
ENSG00000262664	18.5	20.034	21.257	25.617	22.152	23.255	395.62	430.64	335.73	405.79	400.23	361.85	OVCA2	OVCA2 serine hydrolase domain containing [Source:HGNC Symbol;Acc:HGNC:24203]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0016787//hydrolase activity	GO:0032526//response to retinoic acid	--
ENSG00000262730	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000262814	40.566	43.259	42.44	49.863	45.527	48.53	849	910	656	773	805	739	MRPL12	mitochondrial ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10378]	Genetic Information Processing	Translation	ko03010//Ribosome	K02935	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005762//mitochondrial large ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	"GO:0006390//mitochondrial transcription;GO:0006412//translation;GO:0032543//mitochondrial translation;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000262874	0.072	0.205	0.049	0	0	0.05	2	4	1	0	0	1	C19orf84	chromosome 19 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:27112]	-	-	-	-	-	-	-	--
ENSG00000262919	9.206	9.703	8.212	11.357	9.565	9.84	232	245	153	213	204	182	CCNQ	cyclin Q [Source:HGNC Symbol;Acc:HGNC:28434]	-	-	-	-	GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus	GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity	GO:0006357//regulation of transcription by RNA polymerase II;GO:0050790//regulation of catalytic activity;GO:1902749//regulation of cell cycle G2/M phase transition	--
ENSG00000263001	151.742	139.582	144.376	114.78	119.617	130.536	13745	12737	9609	7735	9199	8615	GTF2I	general transcription factor IIi [Source:HGNC Symbol;Acc:HGNC:4659]	Environmental Information Processing;Genetic Information Processing	Signal transduction;Transcription	ko04022//cGMP-PKG signaling pathway;ko03022//Basal transcription factors	K03121;K03121	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0061629//RNA polymerase II-specific DNA-binding transcription factor binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0016525//negative regulation of angiogenesis;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0100026//positive regulation of DNA repair by transcription from RNA polymerase II promoter"	GTF2I
ENSG00000263002	2.532	2.251	2.009	2.713	2.66	2.531	183	148	105	138	141	123	ZNF234	zinc finger protein 234 [Source:HGNC Symbol;Acc:HGNC:13027]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000263020	0.274	0.585	0.239	0.245	0.209	0.113	14.16	23.22	9.11	7.96	6.98	4.26	LY6G5B	novel protein	-	-	-	-	GO:0005956//protein kinase CK2 complex	GO:0019887//protein kinase regulator activity	GO:0016055//Wnt signaling pathway;GO:0050790//regulation of catalytic activity	--
ENSG00000263155	0.415	0.227	0.095	0.698	0.201	0.091	20.64	11.33	0.89	24.95	8.45	3.21	MYZAP	myocardial zonula adherens protein [Source:HGNC Symbol;Acc:HGNC:43444]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030018//Z disc;GO:0030054//cell junction;GO:0030864//cortical actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031674//I band	GO:0005515//protein binding	GO:0035556//intracellular signal transduction	--
ENSG00000263201	0	0	0	0	0	0	0	0	0	0	0	0	DPEP2NB	DPEP2 neighbor [Source:HGNC Symbol;Acc:HGNC:52385]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000263353	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4A	peptidylprolyl isomerase A like 4A [Source:HGNC Symbol;Acc:HGNC:24369]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000263429	0	0	0	0	0	0	0	0	0	0	0	0	TMEM238L	transmembrane protein 238 like [Source:HGNC Symbol;Acc:HGNC:44356]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000263465	23.656	16.691	21.584	18.161	22.048	23.689	1182	1092	836	782	910	827	SRSF8	serine and arginine rich splicing factor 8 [Source:HGNC Symbol;Acc:HGNC:16988]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Transcription	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome	K12891;K12891	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000263513	0	0.08	0.136	0.149	0.074	0.338	0	2.77	5	5.5	3.12	12.21	FAM72C	family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000263528	0.789	0.863	0.807	1.222	1.21	0.865	53	57	36	56	41	40	IKBKE	inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Infectious disease: viral;Immune system;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Endocrine and metabolic disease;Immune system;Immune system;Immune system;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05417//Lipid and atherosclerosis;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04936//Alcoholic liver disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04657//IL-17 signaling pathway;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211;K07211	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016605//PML body;GO:0031966//mitochondrial membrane;GO:1902554//serine/threonine protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008384//IkappaB kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0007252//I-kappaB phosphorylation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010467//gene expression;GO:0010884//positive regulation of lipid storage;GO:0016310//phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034340//response to type I interferon;GO:0035456//response to interferon-beta;GO:0038061//NIK/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein-containing complex assembly;GO:0048255//mRNA stabilization;GO:0051091//positive regulation of DNA-binding transcription factor activity;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0097400//interleukin-17-mediated signaling pathway;GO:0098586//cellular response to virus	--
ENSG00000263620	5.471	5.071	8.202	8.836	8.032	7.061	52.2	48.63	57.8	62.45	64.75	49.02	VAMP3	novel protein	Organismal Systems;Organismal Systems	Environmental adaptation;Environmental adaptation	ko04713//Circadian entrainment;ko04710//Circadian rhythm	K21944;K21944	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031201//SNARE complex;GO:0031410//cytoplasmic vesicle;GO:0045202//synapse;GO:0110165//cellular anatomical entity	GO:0005484//SNAP receptor activity;GO:0017075//syntaxin-1 binding;GO:0019905//syntaxin binding	GO:0006906//vesicle fusion;GO:0016192//vesicle-mediated transport;GO:0035493//SNARE complex assembly	--
ENSG00000263639	0	0	0	0	0	0	0	0	0	0	0	0	MSMB	microseminoprotein beta [Source:HGNC Symbol;Acc:HGNC:7372]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000263715	0.68	0.908	0.92	1.063	0.593	1.106	38	51	38	44	28	45	LINC02210-CRHR1	LINC02210-CRHR1 readthrough [Source:HGNC Symbol;Acc:HGNC:51483]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Signal transduction;Endocrine and metabolic disease;Nervous system	ko04080//Neuroactive ligand-receptor interaction;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome;ko04730//Long-term depression	K04578;K04578;K04578;K04578	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0007166//cell surface receptor signaling pathway;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000263761	0	0	0	0	0	0	0	0	0	0	0	0	GDF2	growth differentiation factor 2 [Source:HGNC Symbol;Acc:HGNC:4217]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K05503	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0070062//extracellular exosome	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008083//growth factor activity	"GO:0001503//ossification;GO:0001525//angiogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001570//vasculogenesis;GO:0001649//osteoblast differentiation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006879//cellular iron ion homeostasis;GO:0008156//negative regulation of DNA replication;GO:0010596//negative regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0016525//negative regulation of angiogenesis;GO:0030308//negative regulation of cell growth;GO:0030509//BMP signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0032924//activin receptor signaling pathway;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048514//blood vessel morphogenesis;GO:0051216//cartilage development;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060395//SMAD protein signal transduction;GO:0061036//positive regulation of cartilage development;GO:0071773//cellular response to BMP stimulus;GO:2000279//negative regulation of DNA biosynthetic process"	--
ENSG00000263809	0	0	0	0	0	0	0	0	0	0	0	0	RPL26	novel protein	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02898;K02898	GO:0005829//cytosol;GO:0005840//ribosome;GO:0015934//large ribosomal subunit	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0010467//gene expression	--
ENSG00000263874	0	0	0	0.106	0.015	0.054	0	0	0	6	1	3	LINC00672	long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000263956	6.607	6.473	6.723	5.408	6.212	5.299	694.11	691.1	513.6	418.16	531.24	408.55	NBPF11	NBPF member 11 [Source:HGNC Symbol;Acc:HGNC:31993]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000263961	0	0	0	0	0.078	0	0	0	0	0	1	0	RHEX	regulator of hemoglobinization and erythroid cell expansion [Source:HGNC Symbol;Acc:HGNC:25341]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005128//erythropoietin receptor binding;GO:0005515//protein binding	GO:0030154//cell differentiation;GO:0036018//cellular response to erythropoietin;GO:0038162//erythropoietin-mediated signaling pathway;GO:0043249//erythrocyte maturation;GO:0045648//positive regulation of erythrocyte differentiation	--
ENSG00000264006	0	0	0	0	0	0	0	0	0	0	0	0	AKR1C8P	"aldo-keto reductase family 1 member C8, pseudogene [Source:HGNC Symbol;Acc:HGNC:23469]"	Metabolism;Human Diseases;Metabolism;Metabolism;Organismal Systems;Metabolism	Global and overview maps;Cancer: overview;Lipid metabolism;Lipid metabolism;Endocrine system;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko05208//Chemical carcinogenesis - reactive oxygen species;ko00590//Arachidonic acid metabolism;ko00140//Steroid hormone biosynthesis;ko04913//Ovarian steroidogenesis;ko00790//Folate biosynthesis	K04119;K04119;K04119;K04119;K04119;K04119	GO:0005737//cytoplasm	GO:0004033//aldo-keto reductase (NADP) activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity	-	--
ENSG00000264058	1.095	1.733	1.204	1.268	1.824	1.211	112.28	178.56	91.18	96.31	158	90.33	KRT222	novel transcript	-	-	-	-	-	-	-	--
ENSG00000264187	0.254	0.445	0.287	0.081	0.346	0.126	8.92	15.69	7.45	2.11	10.26	3.21	FLCN	novel protein	Environmental Information Processing;Human Diseases	Signal transduction;Cancer: specific types	ko04150//mTOR signaling pathway;ko05211//Renal cell carcinoma	K09594;K09594	-	-	-	--
ENSG00000264230	4.953	6.065	4.473	10.828	10.822	7.575	196.03	238.58	132.92	318.36	365.14	216.32	ANXA8L1	annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334]	-	-	-	-	GO:0005737//cytoplasm	GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0046872//metal ion binding	GO:0007032//endosome organization;GO:0016197//endosomal transport;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:1900138//negative regulation of phospholipase A2 activity	--
ENSG00000264324	0.043	0.076	0.062	0.052	0.091	0.363	4.49	8.02	4.81	4.05	8.04	27.71	DCTN1	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Infectious disease: bacterial;Excretory system	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K04648;K04648;K04648;K04648;K04648	-	-	-	--
ENSG00000264343	25.075	21.463	22.167	21.828	25.054	22.108	814.29	733	544.09	522.68	661.56	495.3	NOTCH2NLA	notch 2 N-terminal like A [Source:HGNC Symbol;Acc:HGNC:31862]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Immune system;Signal transduction;Development and regeneration	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway;ko04320//Dorso-ventral axis formation	K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0021987//cerebral cortex development;GO:0030154//cell differentiation;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000264364	24.938	25.98	27.475	30.54	28.436	25.387	3521	3687	2865	3194	3392	2608	DYNLL2	dynein light chain LC8-type 2 [Source:HGNC Symbol;Acc:HGNC:24596]	Human Diseases;Organismal Systems	Infectious disease: bacterial;Excretory system	ko05132//Salmonella infection;ko04962//Vasopressin-regulated water reabsorption	K10418;K10418	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0030286//dynein complex;GO:0031475//myosin V complex;GO:0097542//ciliary tip;GO:0097731//9+0 non-motile cilium;GO:0098794//postsynapse;GO:0098978//glutamatergic synapse	GO:0005515//protein binding;GO:0045505//dynein intermediate chain binding;GO:0051959//dynein light intermediate chain binding	GO:0007017//microtubule-based process;GO:0060271//cilium assembly	--
ENSG00000264424	0	0.024	0.041	0.097	0.114	0.044	0	3	3.75	9	12	4	MYH4	myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]	-	-	-	-	GO:0005737//cytoplasm;GO:0005859//muscle myosin complex;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0032982//myosin filament	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003725//double-stranded RNA binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0051015//actin filament binding	GO:0006936//muscle contraction;GO:0030048//actin filament-based movement;GO:0030049//muscle filament sliding;GO:0046034//ATP metabolic process	--
ENSG00000264522	9.218	8.945	10.825	9.039	7.987	9.679	1261	1204	920	815	927	850	OTUD7B	OTU deubiquitinase 7B [Source:HGNC Symbol;Acc:HGNC:16683]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0004843//thiol-dependent deubiquitinase;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:1990380//Lys48-specific deubiquitinase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0002385//mucosal immune response;GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0032717//negative regulation of interleukin-8 production;GO:0035871//protein K11-linked deubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1900181//negative regulation of protein localization to nucleus	--
ENSG00000264545	0	0	0	0.153	0	0	0	0	0	1.46	0	0	MTAP	novel transcript	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism	K00772;K00772	-	GO:0003824//catalytic activity;GO:0016763//pentosyltransferase activity;GO:0017061//S-methyl-5-thioadenosine phosphorylase activity	GO:0006166//purine ribonucleoside salvage;GO:0009116//nucleoside metabolic process	--
ENSG00000264668	0.481	0.372	0.328	0.504	0.991	0	28.88	22.47	14.57	22.44	50.3	0	ZFP41	novel protein	-	-	-	-	-	-	-	zf-C2H2
ENSG00000264717	0	0	0	0	0	0	0	0	0	0	0	0	NPY4R2	neuropeptide Y receptor Y4-2 [Source:HGNC Symbol;Acc:HGNC:52383]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K04206	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001602//pancreatic polypeptide receptor activity;GO:0004930//G protein-coupled receptor activity;GO:0004983//neuropeptide Y receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway	--
ENSG00000264813	0	0	0	0	0	0	0	0	0	0	0	0	ACE	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cardiovascular disease;Infectious disease: parasitic;Cardiovascular disease;Endocrine system;Endocrine system	ko05171//Coronavirus disease - COVID-19;ko05415//Diabetic cardiomyopathy;ko05142//Chagas disease;ko05410//Hypertrophic cardiomyopathy;ko04924//Renin secretion;ko04614//Renin-angiotensin system	K01283;K01283;K01283;K01283;K01283;K01283	GO:0016020//membrane	GO:0004180//carboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008241//peptidyl-dipeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis	--
ENSG00000265107	0.137	0.075	0.082	0.179	0.156	0.042	9	5	4	6	4	2	GJA5	gap junction protein alpha 5 [Source:HGNC Symbol;Acc:HGNC:4279]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042995//cell projection	GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0055077//gap junction hemi-channel activity;GO:0071253//connexin binding;GO:0086020//gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling;GO:0086075//gap junction channel activity involved in cardiac conduction electrical coupling;GO:0086076//gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0086078//gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling;GO:0086079//gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling;GO:0097718//disordered domain specific binding	GO:0001525//angiogenesis;GO:0003105//negative regulation of glomerular filtration;GO:0003151//outflow tract morphogenesis;GO:0003158//endothelium development;GO:0003161//cardiac conduction system development;GO:0003174//mitral valve development;GO:0003193//pulmonary valve formation;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:0006813//potassium ion transport;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007507//heart development;GO:0010643//cell communication by chemical coupling;GO:0010644//cell communication by electrical coupling;GO:0010649//regulation of cell communication by electrical coupling;GO:0010652//positive regulation of cell communication by chemical coupling;GO:0016264//gap junction assembly;GO:0042311//vasodilation;GO:0045776//negative regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0048844//artery morphogenesis;GO:0055085//transmembrane transport;GO:0055117//regulation of cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0086021//SA node cell to atrial cardiac muscle cell communication by electrical coupling;GO:0086044//atrial cardiac muscle cell to AV node cell communication by electrical coupling;GO:0086053//AV node cell to bundle of His cell communication by electrical coupling;GO:0086054//bundle of His cell to Purkinje myocyte communication by electrical coupling;GO:0086055//Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0098904//regulation of AV node cell action potential;GO:0098905//regulation of bundle of His cell action potential;GO:0098906//regulation of Purkinje myocyte action potential;GO:0098910//regulation of atrial cardiac muscle cell action potential;GO:1990029//vasomotion	--
ENSG00000265118	0	0	0	0	0	0	0	0	0	0	0	0	EVI2A	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000265190	6.471	5.456	4.514	13.396	14.637	13.163	267.97	229.42	140.08	413.64	513.86	399.68	ANXA8	annexin A8 [Source:HGNC Symbol;Acc:HGNC:546]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031902//late endosome membrane;GO:0062023//collagen-containing extracellular matrix	"GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0046872//metal ion binding;GO:0051015//actin filament binding"	GO:0007032//endosome organization;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0016197//endosomal transport;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:1900138//negative regulation of phospholipase A2 activity	--
ENSG00000265203	0.045	0.089	0.061	0.015	0.027	0.062	4	8	4	1	2	4	RBP3	retinol binding protein 3 [Source:HGNC Symbol;Acc:HGNC:9921]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0033165//interphotoreceptor matrix;GO:0090658//cone matrix sheath;GO:1903561//extracellular vesicle	GO:0005501//retinoid binding;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity;GO:0016918//retinal binding;GO:0019841//retinol binding	GO:0001523//retinoid metabolic process;GO:0006508//proteolysis;GO:0006629//lipid metabolic process;GO:0007601//visual perception	--
ENSG00000265241	49.731	51.199	53.761	59.221	50.684	53.586	2113	2202	1636	1501	1664	1659	RBM8A	RNA binding motif protein 8A [Source:HGNC Symbol;Acc:HGNC:9905]	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12876;K12876;K12876	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0030425//dendrite;GO:0035145//exon-exon junction complex;GO:0043025//neuronal cell body;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0071013//catalytic step 2 spliceosome;GO:1990501//exon-exon junction subcomplex mago-y14	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0006417//regulation of translation;GO:0008380//RNA splicing;GO:0050684//regulation of mRNA processing;GO:0051028//mRNA transport;GO:2000622//regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000265303	0	0	0	0	0	0	0	0	0	0	0	0	SMG8	novel protein	-	-	-	-	-	-	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"	--
ENSG00000265354	33.302	35.427	33.681	34.075	30.163	38.977	822	878.94	614	623	629	700	TIMM23	translocase of inner mitochondrial membrane 23 [Source:HGNC Symbol;Acc:HGNC:17312]	Organismal Systems	Aging	ko04212//Longevity regulating pathway - worm	K17794	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005744//TIM23 mitochondrial import inner membrane translocase complex;GO:0005758//mitochondrial intermembrane space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031305//integral component of mitochondrial inner membrane	GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0006626//protein targeting to mitochondrion;GO:0006886//intracellular protein transport;GO:0015031//protein transport;GO:0030150//protein import into mitochondrial matrix	--
ENSG00000265491	4.201	3.728	3.809	3.462	3.511	3.358	796	710	533	485.94	562	463	RNF115	ring finger protein 115 [Source:HGNC Symbol;Acc:HGNC:18154]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0051865//protein autoubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination	--
ENSG00000265590	9.321	8.267	8.513	6.419	6.232	4.588	194.95	172.38	139.43	105.36	111.5	69.45	CFAP298-TCP10L	CFAP298-TCP10L readthrough [Source:HGNC Symbol;Acc:HGNC:54636]	-	-	-	-	-	-	GO:0003352//regulation of cilium movement	--
ENSG00000265681	314.694	318.366	292.108	272.85	238.52	250.853	4195.08	4268.5	2914.99	2693.24	2705.8	2420.19	RPL17	ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02880;K02880	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding	GO:0002181//cytoplasmic translation;GO:0006412//translation	--
ENSG00000265690	0.524	0.13	0.709	0.398	0.675	0.63	15.65	4	16	9	17.43	14	FBXL8	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	-	GO:0000086//G2/M transition of mitotic cell cycle;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0051726//regulation of cell cycle	--
ENSG00000265763	0.411	0.573	0.505	0.555	0.438	0.81	30	42	27	30	27	43	ZNF488	zinc finger protein 488 [Source:HGNC Symbol;Acc:HGNC:23535]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0014003//oligodendrocyte development;GO:0031643//positive regulation of myelination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048714//positive regulation of oligodendrocyte differentiation"	Others
ENSG00000265808	14.777	13.865	14.82	11.273	12.45	13.085	2041	1906	1507	1139	1457	1300	SEC22B	"SEC22 homolog B, vesicle trafficking protein [Source:HGNC Symbol;Acc:HGNC:10700]"	Cellular Processes;Human Diseases;Genetic Information Processing	"Transport and catabolism;Infectious disease: bacterial;Folding, sorting and degradation"	ko04145//Phagosome;ko05134//Legionellosis;ko04130//SNARE interactions in vesicular transport	K08517;K08517;K08517	GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0030670//phagocytic vesicle membrane;GO:0031201//SNARE complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042470//melanosome	GO:0005484//SNAP receptor activity;GO:0005515//protein binding	"GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0045732//positive regulation of protein catabolic process;GO:0048280//vesicle fusion with Golgi apparatus;GO:0061025//membrane fusion;GO:1902902//negative regulation of autophagosome assembly"	--
ENSG00000265817	3.022	3.043	3.24	1.843	2.714	2.972	303.88	273.76	220.72	133.57	197.95	203.72	FSBP	fibrinogen silencer binding protein [Source:HGNC Symbol;Acc:HGNC:43653]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000265818	0	0	0	0	0	0	0	0	0	0	0	0	EEF1E1-BLOC1S5	EEF1E1-BLOC1S5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49187]	-	-	-	-	GO:0005737//cytoplasm;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex	-	"GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator"	--
ENSG00000265972	22.073	23.71	21.974	13.891	18.197	12.454	1330	1436	966	620	870	546	TXNIP	thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952]	Organismal Systems	Immune system	ko04621//NOD-like receptor signaling pathway	K20910	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol	GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006606//protein import into nucleus;GO:0006979//response to oxidative stress;GO:0007049//cell cycle;GO:0009410//response to xenobiotic stimulus;GO:0009612//response to mechanical stimulus;GO:0009749//response to glucose;GO:0015031//protein transport;GO:0030216//keratinocyte differentiation;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0042127//regulation of cell population proliferation;GO:0042542//response to hydrogen peroxide;GO:0043065//positive regulation of apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0051592//response to calcium ion;GO:0051782//negative regulation of cell division;GO:0071228//cellular response to tumor cell	--
ENSG00000266028	4.513	4.721	4.512	4.392	5.131	4.752	495.71	533.28	382.81	352.4	457.79	350.94	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:19751]	Organismal Systems	Development and regeneration	ko04360//Axon guidance	K07526	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043197//dendritic spine;GO:0044327//dendritic spine head;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0045335//phagocytic vesicle	GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity	GO:0003363//lamellipodium assembly involved in ameboidal cell migration;GO:0007165//signal transduction;GO:0007399//nervous system development;GO:0021816//extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration;GO:0030336//negative regulation of cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043547//positive regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0048812//neuron projection morphogenesis;GO:0051014//actin filament severing;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0060996//dendritic spine development;GO:1904861//excitatory synapse assembly;GO:1904862//inhibitory synapse assembly;GO:2001223//negative regulation of neuron migration	--
ENSG00000266074	3.818	3.906	4.196	4.179	4.376	4.52	840	872	686	685	810	719	BAHCC1	BAH domain and coiled-coil containing 1 [Source:HGNC Symbol;Acc:HGNC:29279]	-	-	-	-	-	GO:0003682//chromatin binding	-	--
ENSG00000266076	0	0	0	0	0	0	0	0	0	0	0	0	CEP112	novel transcript	-	-	-	-	-	-	-	--
ENSG00000266086	1.582	1.895	1.154	2.31	2.334	2.863	74.49	89.66	40.14	80.58	92.83	98.08	SRSF1	novel transcript	Human Diseases;Genetic Information Processing;Organismal Systems	Infectious disease: viral;Transcription;Immune system	ko05168//Herpes simplex virus 1 infection;ko03040//Spliceosome;ko04657//IL-17 signaling pathway	K12890;K12890;K12890	-	-	-	--
ENSG00000266094	0.455	0.837	0.095	0.588	0.876	0.917	36	61	5	28	58	47	RASSF5	Ras association domain family member 5 [Source:HGNC Symbol;Acc:HGNC:17609]	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Cell growth and death;Immune system;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04218//Cellular senescence;ko04670//Leukocyte transendothelial migration;ko05223//Non-small cell lung cancer	K08015;K08015;K08015;K08015;K08015;K08015	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0031398//positive regulation of protein ubiquitination;GO:0042981//regulation of apoptotic process;GO:1900180//regulation of protein localization to nucleus	--
ENSG00000266173	11.521	12.706	12.819	12.101	10.824	13.678	467	515	396	380	412	422	STRADA	STE20 related adaptor alpha [Source:HGNC Symbol;Acc:HGNC:30172]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04150//mTOR signaling pathway;ko04152//AMPK signaling pathway	K08271;K08271	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0140535//intracellular protein-containing complex;GO:1902554//serine/threonine protein kinase complex	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity;GO:0043539//protein serine/threonine kinase activator activity	GO:0006468//protein phosphorylation;GO:0006611//protein export from nucleus;GO:0007049//cell cycle;GO:0032147//activation of protein kinase activity;GO:0070314//G1 to G0 transition;GO:0071902//positive regulation of protein serine/threonine kinase activity	--
ENSG00000266200	0	0	0	0	0	0	0	0	0	0	0	0	PNLIPRP2	pancreatic lipase related protein 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:9157]	Metabolism;Organismal Systems;Metabolism;Organismal Systems	Global and overview maps;Digestive system;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04972//Pancreatic secretion;ko00561//Glycerolipid metabolism;ko04975//Fat digestion and absorption	K14075;K14075;K14075;K14075	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0004620//phospholipase activity;GO:0004806//triglyceride lipase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016298//lipase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding;GO:0047372//acylglycerol lipase activity;GO:0047714//galactolipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0102549//1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity	GO:0006629//lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006968//cellular defense response;GO:0009395//phospholipid catabolic process;GO:0009617//response to bacterium;GO:0016042//lipid catabolic process;GO:0019376//galactolipid catabolic process;GO:0019433//triglyceride catabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0044241//lipid digestion;GO:0044258//intestinal lipid catabolic process	--
ENSG00000266202	0	0	0	0	0	0	0	0	0	0	0	0	LYRM9	novel protein	-	-	-	-	-	-	-	--
ENSG00000266265	0.014	0.082	0.019	0	0.114	0	1	6	1	0	7	0	KLF14	Kruppel like factor 14 [Source:HGNC Symbol;Acc:HGNC:23025]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:1902070//positive regulation of sphingolipid mediated signaling pathway	zf-C2H2
ENSG00000266302	0.313	0.27	0.306	0.163	0.157	0.257	57.22	49.48	41.26	22.01	24.17	34.13	CCDC144A	novel transcript	-	-	-	-	-	-	-	--
ENSG00000266338	5.948	5.745	5.925	6.16	5.479	5.358	547.48	551.06	418.59	439.39	446.94	371.68	NBPF15	NBPF member 15 [Source:HGNC Symbol;Acc:HGNC:28791]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000266412	72.486	68.518	71.135	66.289	66.108	69.317	5172	4928	3763	3449	3946	3605	NCOA4	nuclear receptor coactivator 4 [Source:HGNC Symbol;Acc:HGNC:7671]	Human Diseases;Cellular Processes;Human Diseases	Cancer: overview;Cell growth and death;Cancer: specific types	ko05200//Pathways in cancer;ko04216//Ferroptosis;ko05216//Thyroid cancer	K09289;K09289;K09289	GO:0005634//nucleus;GO:0044754//autolysosome	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0006622//protein targeting to lysosome;GO:0006879//cellular iron ion homeostasis;GO:0008584//male gonad development;GO:0009725//response to hormone;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071391//cellular response to estrogen stimulus;GO:0071394//cellular response to testosterone stimulus"	--
ENSG00000266472	14.653	14.331	17.568	15.531	12.148	14.957	386	380	335	303	268	299	MRPS21	mitochondrial ribosomal protein S21 [Source:HGNC Symbol;Acc:HGNC:14046]	Genetic Information Processing	Translation	ko03010//Ribosome	K02970	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000266524	0	0	0	0	0	0	0	0	0	0	0	0	GDF10	growth differentiation factor 10 [Source:HGNC Symbol;Acc:HGNC:4215]	Environmental Information Processing	Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction	K22674	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0005125//cytokine activity;GO:0008083//growth factor activity	GO:0001501//skeletal system development;GO:0001503//ossification;GO:0001649//osteoblast differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0021549//cerebellum development;GO:0030278//regulation of ossification;GO:0042698//ovulation cycle;GO:0045444//fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0060395//SMAD protein signal transduction;GO:0071559//response to transforming growth factor beta	--
ENSG00000266714	1.047	0.667	1.15	0.389	0.875	1.054	39	42	47	25	40	29	MYO15B	myosin XVB [Source:HGNC Symbol;Acc:HGNC:14083]	-	-	-	-	GO:0005856//cytoskeleton;GO:0005903//brush border;GO:0016459//myosin complex	GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding	-	--
ENSG00000266728	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000266826	0	0	0	0	0	0	0	0	0	0	0	0	IGBP1P2	immunoglobulin (CD79A) binding protein 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:43611]	Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04136//Autophagy - other	K17606;K17606	GO:0005829//cytosol	GO:0051721//protein phosphatase 2A binding	GO:0009966//regulation of signal transduction;GO:0035303//regulation of dephosphorylation	--
ENSG00000266953	0.21	0	0	0	0	0	2.72	0	0	0	0	0	PDCD2L	"novel protein, readthrough between GPI and PDCD2"	-	-	-	-	-	GO:0004347//glucose-6-phosphate isomerase activity;GO:0016853//isomerase activity	GO:0006094//gluconeogenesis;GO:0006096//glycolytic process	--
ENSG00000266964	37.431	29.644	38.405	54.351	42.868	42.272	441	345	339	472	426	368	FXYD1	FXYD domain containing ion transport regulator 1 [Source:HGNC Symbol;Acc:HGNC:4025]	Environmental Information Processing	Signal transduction	ko04024//cAMP signaling pathway	K13360	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005901//caveola;GO:0014704//intercalated disc;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0030315//T-tubule;GO:0042383//sarcolemma	GO:0005254//chloride channel activity;GO:0017080//sodium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:0099106//ion channel regulator activity	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0006814//sodium ion transport;GO:0006821//chloride transport;GO:0006936//muscle contraction;GO:0008016//regulation of heart contraction;GO:0010734//negative regulation of protein glutathionylation;GO:0043269//regulation of ion transport;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:2000649//regulation of sodium ion transmembrane transporter activity	--
ENSG00000266967	12.321	11.413	11.637	12.732	12.891	12.063	292.97	286.76	206.83	241.6	259.57	203.03	AARSD1	alanyl-tRNA synthetase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28417]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000166//nucleotide binding;GO:0002196//Ser-tRNA(Ala) hydrolase activity;GO:0003674//molecular_function;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004813//alanine-tRNA ligase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0140101//catalytic activity, acting on a tRNA"	GO:0006399//tRNA metabolic process;GO:0006412//translation;GO:0006419//alanyl-tRNA aminoacylation;GO:0006450//regulation of translational fidelity;GO:0008150//biological_process;GO:0043039//tRNA aminoacylation;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000266997	0	0	0	0	0	0	0	0	0	0	0	0	MYO5B	novel protein	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K10357	-	-	-	--
ENSG00000267001	5.42	5.896	9.442	4.302	4.285	7.289	61.05	66.75	78.54	35.89	40.77	59.73	SLC39A3	novel protein	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05010//Alzheimer disease;ko05012//Parkinson disease	K14709;K14709	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005385//zinc ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity	GO:0030001//metal ion transport;GO:0055085//transmembrane transport;GO:0071577//zinc ion transmembrane transport	--
ENSG00000267022	0.672	0.096	0.194	0.793	0.281	0.714	52.53	7.57	11.21	45.89	18.55	40.59	ZNF223	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000267041	0.313	0.483	0.163	0.128	0.411	0.191	50	31	19	15	21	22	ZNF850	zinc finger protein 850 [Source:HGNC Symbol;Acc:HGNC:27994]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000267059	23.44	21.673	22.626	26.17	23.166	16.496	487.17	452.76	347.31	402.88	406.78	249.46	UQCR11	"novel transcript, readthrough between UQCR11 and MBD3"	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Organismal Systems	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Circulatory system	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko04260//Cardiac muscle contraction	K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420;K00420	-	-	-	--
ENSG00000267060	0.167	0.24	0.293	0.258	0.039	0.372	5	8	6.93	6.11	1	10	PTGES3L	prostaglandin E synthase 3 like [Source:HGNC Symbol;Acc:HGNC:43943]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol	GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding	GO:0006457//protein folding;GO:0051131//chaperone-mediated protein complex assembly	--
ENSG00000267110	0	0	0	0	0	0	0	0	0	0	0	0	DNAAF3	novel transcript	-	-	-	-	-	-	GO:0044458//motile cilium assembly;GO:0070286//axonemal dynein complex assembly	--
ENSG00000267120	0.101	0.091	0.394	0.34	0.178	0.182	4.02	3.64	11.63	10.06	6.01	5.3	U2AF1L4	novel transcript	Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Transcription	ko05131//Shigellosis;ko03040//Spliceosome	K12836;K12836	GO:0089701//U2AF complex	GO:0003723//RNA binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000267127	0.084	0.247	0.029	0.226	0.051	0.03	2	8	1	4	2	1	RBFA	novel protein	-	-	-	-	-	-	-	--
ENSG00000267140	0	0	0	0.438	0	0	0	0	0	3.06	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000267157	0	0	0	0	0	0	0	0	0	0	0	0	DUS3L	novel protein	-	-	-	-	-	GO:0017150//tRNA dihydrouridine synthase activity	GO:0002943//tRNA dihydrouridine synthesis	--
ENSG00000267168	0	0	0	0	0	0	0	0	0	0	0	0	METTL23	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0008168//methyltransferase activity;GO:0016740//transferase activity	GO:0032259//methylation	--
ENSG00000267173	0	0	0	0	0	0	0	0	0	0	0	0	ZNF112	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000267179	0.402	0	0	0.112	0	0.296	13.04	0	0	1.17	0	6.97	ZNF69	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000267206	0	0	0	0	0	0	0	0	0	0	0	0	LCN6	lipocalin 6 [Source:HGNC Symbol;Acc:HGNC:17337]	-	-	-	-	GO:0005576//extracellular region	GO:0036094//small molecule binding	GO:0007338//single fertilization	--
ENSG00000267221	0.116	0.116	0.227	0.07	0.245	0.16	9	9	13	4	16	9	C17orf113	chromosome 17 open reading frame 113 [Source:HGNC Symbol;Acc:HGNC:53437]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000267228	0	0.962	0	0	0	0	0	28.95	0	0	0	0	IER3IP1	novel transcript	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0015031//protein transport	--
ENSG00000267261	0	0	0	0	0	0	0	0	0	0	0	0	RAB5C	novel protein	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Organismal Systems	Infectious disease: bacterial;Transport and catabolism;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Infectious disease: parasitic;Excretory system	ko05132//Salmonella infection;ko04144//Endocytosis;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko04145//Phagosome;ko05146//Amoebiasis;ko04962//Vasopressin-regulated water reabsorption	K07889;K07889;K07889;K07889;K07889;K07889;K07889	GO:0005634//nucleus	GO:0003924//GTPase activity;GO:0004402//histone acetyltransferase activity;GO:0005525//GTP binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation"	--
ENSG00000267281	0	0	0	0	0	0	0	0	0	0	0	0	ATF7-NPFF	ATF7-NPFF readthrough [Source:HGNC Symbol;Acc:HGNC:55073]	-	-	-	-	GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity	"GO:0006355//regulation of transcription, DNA-templated"	TF_bZIP
ENSG00000267303	0	0.329	1.276	0	0	0	0	12.69	36.15	0	0	0	Raver1	novel transcript	-	-	-	-	GO:0005634//nucleus	GO:0003729//mRNA binding	"GO:0000381//regulation of alternative mRNA splicing, via spliceosome"	--
ENSG00000267314	0.279	0.535	0	0.474	1.278	0.938	3.36	6.47	0	4.22	12.99	8.21	VMAC	"novel protein, readthrough VMAC-CAPS"	-	-	-	-	-	-	-	--
ENSG00000267318	0	0	0	0	0	0	0	0	0	0	0	0	RPS6KB1	novel protein	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Environmental adaptation;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Cancer: overview;Immune system;Cancer: specific types;Signal transduction;Transport and catabolism;Cancer: specific types;Cancer: specific types;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine and metabolic disease;Cancer: overview;Drug resistance: antineoplastic;Cancer: overview;Signal transduction;Aging;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Aging;Development and regeneration;Aging	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05131//Shigellosis;ko04714//Thermogenesis;ko05163//Human cytomegalovirus infection;ko05170//Human immunodeficiency virus 1 infection;ko05205//Proteoglycans in cancer;ko05207//Chemical carcinogenesis - receptor activation;ko04666//Fc gamma R-mediated phagocytosis;ko05225//Hepatocellular carcinoma;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko05224//Breast cancer;ko05226//Gastric cancer;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04931//Insulin resistance;ko05231//Choline metabolism in cancer;ko01522//Endocrine resistance;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04350//TGF-beta signaling pathway;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05212//Pancreatic cancer;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04361//Axon regeneration;ko04212//Longevity regulating pathway - worm	K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688;K04688	-	-	-	--
ENSG00000267335	0	0	0	0	0.073	0	0	0	0	0	1	0	CGB1	novel protein	-	-	-	-	GO:0005576//extracellular region	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0007165//signal transduction	--
ENSG00000267360	0	0	0	0	0	0.171	0	0	0	0	0	2.49	ZNF585B	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000267368	2.474	2	2.864	2.751	1.41	2.668	68.87	55.97	58.88	56.73	33.15	54.03	UPK3BL1	uroplakin 3B like 1 [Source:HGNC Symbol;Acc:HGNC:37278]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000267385	0.053	0.027	0	0.088	0.063	0.074	2	1	0	2.44	2	2	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000267426	0	0	0	0	0	0	0	0	0	0	0	0	FBF1	novel protein	-	-	-	-	-	-	-	--
ENSG00000267467	0	0	0	0	0	0	0	0	0	0	0	0	APOC4	apolipoprotein C4 [Source:HGNC Symbol;Acc:HGNC:611]	-	-	-	-	GO:0005576//extracellular region;GO:0034361//very-low-density lipoprotein particle;GO:0034364//high-density lipoprotein particle	GO:0005319//lipid transporter activity;GO:0005515//protein binding	GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0010890//positive regulation of sequestering of triglyceride;GO:0070328//triglyceride homeostasis	--
ENSG00000267477	0	0	0	0	0	0	0	0	0	0	0	0	ZNF653	novel protein	-	-	-	-	-	-	-	--
ENSG00000267508	2.74	2.68	3.988	2.884	1.684	4.827	159	191	131	86	88	99	ZNF285	zinc finger protein 285 [Source:HGNC Symbol;Acc:HGNC:13079]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000267534	0.648	0.737	0.556	0.465	0.611	0.691	49	56	31.03	26	39	38	S1PR2	sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04071//Sphingolipid signaling pathway	K04292;K04292	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001664//G protein-coupled receptor binding;GO:0004930//G protein-coupled receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008528//G protein-coupled peptide receptor activity;GO:0038036//sphingosine-1-phosphate receptor activity	GO:0003376//sphingosine-1-phosphate receptor signaling pathway;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0019222//regulation of metabolic process;GO:0031532//actin cytoskeleton reorganization;GO:0046847//filopodium assembly;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:1903142//positive regulation of establishment of endothelial barrier;GO:1904706//negative regulation of vascular associated smooth muscle cell proliferation	--
ENSG00000267552	0	0	0	0	0	0	0	0	0	0	0	0	ZNF607	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000267561	0	0.044	0.05	0	0	0	0	1.83	1.54	0	0	0	HS2ST1	novel protein	Metabolism	Glycan biosynthesis and metabolism	ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02513	GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity	-	--
ENSG00000267618	0	0	0	0	0	0	0	0	0	0	0	0	RAD51D	RAD51L3-RFFL readthrough	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K10871	GO:0005634//nucleus	"GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0008094//ATP-dependent activity, acting on DNA;GO:0046872//metal ion binding"	GO:0006259//DNA metabolic process;GO:0006281//DNA repair	--
ENSG00000267631	0	0	0	0	0	0	0	0	0	0	0	0	CGB1	chorionic gonadotropin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:16721]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm	GO:0005102//signaling receptor binding;GO:0005179//hormone activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000267645	8.025	8.608	8.749	6.262	7.737	7.328	265.98	286.8	214.18	153.74	216.66	176.72	POLR2J2	"novel protein, POLR2J2-UPK3BL readthrough"	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03008;K03008	-	-	-	--
ENSG00000267673	14.332	12.623	15.94	15.447	16.579	13.383	240.3	209.51	184.63	179.24	215.26	155.72	FDX2	ferredoxin 2 [Source:HGNC Symbol;Acc:HGNC:30546]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:1990229//iron-sulfur cluster assembly complex	"GO:0005515//protein binding;GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0016226//iron-sulfur cluster assembly;GO:0022900//electron transport chain;GO:0051353//positive regulation of oxidoreductase activity;GO:0140647//P450-containing electron transport chain	--
ENSG00000267680	4.503	3.319	3.303	3.435	4.118	2.615	327	258	158	189	222	144	ZNF224	zinc finger protein 224 [Source:HGNC Symbol;Acc:HGNC:13017]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0031965//nuclear membrane	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000267699	0.179	0.289	0.079	0.093	0	0	4.57	7.39	1.48	1.75	0	0	ELAC1	novel protein	-	-	-	-	-	-	-	--
ENSG00000267706	0	0	0	0	0.019	0.043	0	0	0	0	1	2	FAM71E2	novel transcript	-	-	-	-	-	-	-	--
ENSG00000267710	0	0	0	0	0	0	0	0	0	0	0	0	EDDM13	epididymal protein 13 [Source:HGNC Symbol;Acc:HGNC:53168]	-	-	-	-	GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000267740	0.575	0.478	0.517	0.72	0.678	2.1	6.04	5.04	4.01	8.41	6.01	16.04	NDUFA11	novel protein	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956;K03956	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0032981//mitochondrial respiratory chain complex I assembly	--
ENSG00000267748	0.101	0	0	0.135	0.241	0	1.02	0	0	1.01	2.06	0	SPINT2	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005886//plasma membrane	GO:0004867//serine-type endopeptidase inhibitor activity	GO:0010951//negative regulation of endopeptidase activity	--
ENSG00000267795	0	0	0	0	0	0	0	0	0	0	0	0	SMIM22	small integral membrane protein 22 [Source:HGNC Symbol;Acc:HGNC:48329]	-	-	-	-	GO:0005768//endosome;GO:0005770//late endosome;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0030335//positive regulation of cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0042127//regulation of cell population proliferation;GO:0051726//regulation of cell cycle;GO:0140042//lipid droplet formation	--
ENSG00000267796	5.389	5.51	5.339	7.108	7.344	5.781	108	113	80.44	105.59	124.82	86.51	LIN37	lin-37 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:33234]	Cellular Processes	Cell growth and death	ko04218//Cellular senescence	K21774	GO:0005654//nucleoplasm;GO:0017053//transcription repressor complex;GO:0031523//Myb complex	GO:0005515//protein binding	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000267855	23.094	10.445	21.739	18.975	14.442	22.862	276.92	126.23	191.62	164.78	146.53	199.11	NDUFA7	NADH:ubiquinone oxidoreductase subunit A7 [Source:HGNC Symbol;Acc:HGNC:7691]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951;K03951	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005761//mitochondrial ribosome;GO:0016020//membrane;GO:0070469//respirasome	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity	"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0009060//aerobic respiration;GO:0032543//mitochondrial translation;GO:0042773//ATP synthesis coupled electron transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport"	--
ENSG00000267881	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM5	"novel protein, readthrough between CEACAM5-CEACAM6"	-	-	-	-	-	-	-	--
ENSG00000267909	0	0.034	0.047	0.031	0	0	0	3	3	2	0	0	CCDC177	coiled-coil domain containing 177 [Source:HGNC Symbol;Acc:HGNC:23243]	-	-	-	-	-	-	-	--
ENSG00000267952	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000267978	0	0	0	0	0	0	0	0	0	0	0	0	MAGEA9B	MAGE family member A9B [Source:HGNC Symbol;Acc:HGNC:31909]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003674//molecular_function;GO:0005515//protein binding;GO:0042826//histone deacetylase binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0008150//biological_process	--
ENSG00000268009	0	0	0.054	0	0	0	0	0	1	0	0	0	SSX4	SSX family member 4 [Source:HGNC Symbol;Acc:HGNC:11338]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268041	0	0	0.097	0	0	0	0	0	3	0	0	0	ERFL	ETS repressor factor like [Source:HGNC Symbol;Acc:HGNC:53894]	-	-	-	-	GO:0005634//nucleus	"GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation"	ETS
ENSG00000268043	4.227	4.332	4.527	2.922	3.986	3.809	556.41	559.14	434.5	276.41	443.71	359.05	NBPF12	NBPF member 12 [Source:HGNC Symbol;Acc:HGNC:24297]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000268083	0	0	0	0	0	0	0	0	0	0	0	0	HNRNPL	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion	"GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003824//catalytic activity;GO:0051750//delta3,5-delta2,4-dienoyl-CoA isomerase activity"	GO:0043484//regulation of RNA splicing	--
ENSG00000268089	0.045	0	0.03	0.04	0.009	0.01	6	0	3	4	1	1	GABRQ	gamma-aminobutyric acid type A receptor subunit theta [Source:HGNC Symbol;Acc:HGNC:14454]	Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signaling molecules and interaction;Nervous system;Substance dependence;Nervous system;Substance dependence	ko04080//Neuroactive ligand-receptor interaction;ko04723//Retrograde endocannabinoid signaling;ko05032//Morphine addiction;ko04727//GABAergic synapse;ko05033//Nicotine addiction	K05192;K05192;K05192;K05192;K05192	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0043005//neuron projection;GO:0043235//receptor complex;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:1902711//GABA-A receptor complex	GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity;GO:0005216//ion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005326//neurotransmitter transmembrane transporter activity;GO:0005515//protein binding;GO:0030594//neurotransmitter receptor activity	GO:0006811//ion transport;GO:0006821//chloride transport;GO:0006836//neurotransmitter transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050877//nervous system process;GO:1902476//chloride transmembrane transport	--
ENSG00000268104	0	0	0	0	0.05	0	0	0	0	0	4	0	SLC6A14	solute carrier family 6 member 14 [Source:HGNC Symbol;Acc:HGNC:11047]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0070062//extracellular exosome	GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0022858//alanine transmembrane transporter activity	GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0009636//response to toxic substance;GO:0032328//alanine transport;GO:0035725//sodium ion transmembrane transport;GO:0089718//amino acid import across plasma membrane	--
ENSG00000268107	0.43	0.021	0.506	0.299	0.141	0.546	20.16	1.01	10.27	10.36	5.57	13.05	ZNF773	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268133	0	0	0	0	0	0	0	0	0	0	0	0	ZNF548	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268163	0	0	0	0	0	0	0	0	0	0	0	0	ZNF772	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268173	2.141	2.374	1.895	2.913	2.112	2.679	228.36	254.53	149.25	230.13	190.35	207.9	PIK3R2	"novel protein, readthrough between PIK3R2 and IFI30"	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649	-	-	-	--
ENSG00000268182	0.019	0.207	0.051	0.358	0.337	0.052	1	11	2	9	15	2	SMIM17	small integral membrane protein 17 [Source:HGNC Symbol;Acc:HGNC:27114]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000268193	0.087	0.107	0.11	0.213	0	0	1.24	1.3	1.15	2.24	0	0	HOMER3	novel transcript	Environmental Information Processing;Organismal Systems	Signal transduction;Nervous system	ko04068//FoxO signaling pathway;ko04724//Glutamatergic synapse	K15010;K15010	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0030425//dendrite	GO:0035256//G protein-coupled glutamate receptor binding	GO:0007216//G protein-coupled glutamate receptor signaling pathway;GO:2001256//regulation of store-operated calcium entry	--
ENSG00000268221	0	0	0	0	0	0	0	0	0	0	0	0	OPN1MW	"opsin 1, medium wave sensitive [Source:HGNC Symbol;Acc:HGNC:4206]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097381//photoreceptor disc membrane	GO:0004930//G protein-coupled receptor activity;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity;GO:0042802//identical protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0032467//positive regulation of cytokinesis;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000268223	0	0	0	0	0.055	0	0	0	0	0	1	0	ARL14EPL	ADP ribosylation factor like GTPase 14 effector protein like [Source:HGNC Symbol;Acc:HGNC:44201]	-	-	-	-	-	-	-	--
ENSG00000268235	0	0	0	0	0	0	0	0	0	0	0	0	TCP11X1	"t-complex 11 family, X-linked 1 [Source:HGNC Symbol;Acc:HGNC:48369]"	-	-	-	-	-	-	-	--
ENSG00000268279	0	0	0	0	0	0.115	0	0	0	0	0	1.13	TMEM43	novel transcript	-	-	-	-	GO:0005639//integral component of nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0071763//nuclear membrane organization	--
ENSG00000268320	0	0	0	0	0	0	0	0	0	0	0	0	SCGB1C2	secretoglobin family 1C member 2 [Source:HGNC Symbol;Acc:HGNC:51242]	-	-	-	-	GO:0005576//extracellular region	GO:0005515//protein binding	-	--
ENSG00000268350	3.003	2.552	1.14	1.344	4.935	1.964	109.72	104.57	36.59	43.86	230.45	54.74	FAM156A	family with sequence similarity 156 member A [Source:HGNC Symbol;Acc:HGNC:30114]	-	-	-	-	GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0035064//methylated histone binding	-	--
ENSG00000268361	0	0	0	0	0	0	0	0	0	0	0	0	XRCC1	novel protein	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10803	GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle	GO:0003684//damaged DNA binding	GO:0000012//single strand break repair;GO:0006284//base-excision repair	--
ENSG00000268400	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0033617//mitochondrial cytochrome c oxidase assembly	--
ENSG00000268434	0	0	0	0	0	0	0	0	0	0	0	0	DMWD	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0072518//Rho-dependent protein serine/threonine kinase activity	GO:0000281//mitotic cytokinesis;GO:0006468//protein phosphorylation;GO:0007266//Rho protein signal transduction;GO:0018107//peptidyl-threonine phosphorylation;GO:0030866//cortical actin cytoskeleton organization;GO:0031032//actomyosin structure organization;GO:0048598//embryonic morphogenesis;GO:0050896//response to stimulus;GO:1901888//regulation of cell junction assembly	--
ENSG00000268447	0	0	0	0	0	0	0	0	0	0	0	0	SSX2B	SSX family member 2B [Source:HGNC Symbol;Acc:HGNC:22263]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15625	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268465	0	0	0	0	0	0	0	0	0	0	0	0	CYTH2	novel protein	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04072//Phospholipase D signaling pathway	K18441;K18441;K18441;K18441;K18441	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0032012//regulation of ARF protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000268480	0	0	0	0	0	0	0	0	0	0	0	0	NFILZ	NFIL3 like basic leucine zipper [Source:HGNC Symbol;Acc:HGNC:52681]	-	-	-	-	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II;GO:0006955//immune response"	--
ENSG00000268500	0	0.048	0	0	0	0	0	3	0	0	0	0	SIGLEC5	sialic acid binding Ig like lectin 5 [Source:HGNC Symbol;Acc:HGNC:10874]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0070821//tertiary granule membrane;GO:0101003//ficolin-1-rich granule membrane	GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000268533	0	0	0	0	0	0	0	0	0	0	0	0	LINC01549	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Cellular Processes	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Transport and catabolism;Neurodegenerative disease;Transport and catabolism	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko04140//Autophagy - animal;ko05017//Spinocerebellar ataxia;ko04137//Mitophagy - animal	K17985;K17985;K17985;K17985;K17985;K17985;K17985	-	-	-	--
ENSG00000268606	0.254	0.063	0.262	0.147	0.298	0	8.77	2.18	6.66	4.26	9.55	0	MAGEA2	MAGE family member A2 [Source:HGNC Symbol;Acc:HGNC:6800]	-	-	-	-	GO:0005634//nucleus;GO:0016605//PML body	GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0140297//DNA-binding transcription factor binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0033234//negative regulation of protein sumoylation;GO:0044257//cellular protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0072331//signal transduction by p53 class mediator;GO:0090398//cellular senescence;GO:1901984//negative regulation of protein acetylation	--
ENSG00000268614	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000268629	0	0	0	0	0	0	0	0	0	0	0	0	TEX13A	testis expressed 13A [Source:HGNC Symbol;Acc:HGNC:11735]	-	-	-	-	GO:0005737//cytoplasm	GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding	-	--
ENSG00000268643	0	0	0	0	0	0	0	0	0	0	0	0	GSK3A	novel protein	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system;Endocrine and metabolic disease;Nervous system	ko05131//Shigellosis;ko04062//Chemokine signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04728//Dopaminergic synapse	K08822;K08822;K08822;K08822	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0010975//regulation of neuron projection development;GO:0032007//negative regulation of TOR signaling;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand	--
ENSG00000268651	0	0	0	0	0	0	0	0	0	0	0	0	CTAG1A	cancer/testis antigen 1A [Source:HGNC Symbol;Acc:HGNC:24198]	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0070525//tRNA threonylcarbamoyladenosine metabolic process	--
ENSG00000268655	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000268696	0	0	0	0	0	0	0	0	0	0	0	0	ZNF723	zinc finger protein 723 [Source:HGNC Symbol;Acc:HGNC:32286]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000268738	0	0	0	0	0	0	0	0	0	0	0	0	HSFX2	"heat shock transcription factor family, X-linked 2 [Source:HGNC Symbol;Acc:HGNC:32701]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000268750	1.162	0.627	0.482	0.112	0.261	0.669	14.84	8.63	4.91	1.32	2.65	6.23	ZNF417	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000268790	0	0	0	0	0.063	0.073	0	0	0	0	1.06	1.05	SMIM7	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000268797	0	0	0	0	0	0	0	0	0	0	0	0	EGLN2	novel protein	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09592;K09592;K09592	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0008198//ferrous iron binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0031545//peptidyl-proline 4-dioxygenase activity	GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0071456//cellular response to hypoxia	--
ENSG00000268799	0	0	0	0	0	0	0	0	0	0	0	0	H3Y2	H3.Y histone 2 [Source:HGNC Symbol;Acc:HGNC:43734]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000268870	0.175	0.1	0.163	0	0.237	0.126	2.24	1.28	1.54	0	2.56	1.17	ZNF799	novel zinc finger protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	--
ENSG00000268902	0.057	0.242	0.041	0.328	0.036	0.663	1	4	0.5	4	0.5	8	CSAG2	CSAG family member 2 [Source:HGNC Symbol;Acc:HGNC:16847]	-	-	-	-	-	-	-	--
ENSG00000268916	0.243	0	0.041	0	0.036	0	4	0	0.5	0	0.5	0	CSAG3	CSAG family member 3 [Source:HGNC Symbol;Acc:HGNC:26237]	-	-	-	-	-	GO:0005515//protein binding	GO:0009410//response to xenobiotic stimulus	--
ENSG00000268940	0	0	0	0	0	0	0	0	0	0	0	0	CT45A1	cancer/testis antigen family 45 member A1 [Source:HGNC Symbol;Acc:HGNC:33267]	-	-	-	-	GO:0032039//integrator complex	GO:0005515//protein binding	GO:0034472//snRNA 3'-end processing	--
ENSG00000268964	0	0	0	0	0	0	0	0	0	0	0	0	ERVV-2	"endogenous retrovirus group V member 2, envelope [Source:HGNC Symbol;Acc:HGNC:39051]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000268975	0	0	0	0	0	0	0	0	0	0	0	0	MIA-RAB4B	MIA-RAB4B readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48352]	-	-	-	-	-	-	-	--
ENSG00000268988	0	0	0	0	0	0.096	0	0	0	0	0	2	SPANXN2	SPANX family member N2 [Source:HGNC Symbol;Acc:HGNC:33175]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000268994	0	0	0	0	0	0	0	0	0	0	0	0	FAM236B	family with sequence similarity 236 member B [Source:HGNC Symbol;Acc:HGNC:52640]	-	-	-	-	-	-	-	--
ENSG00000269026	0	0	0	0	0	0	0	0	0	0	0	0	ZNF776	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269028	2.252	3.566	1.929	1.675	3.645	1.958	49	78	31	27	67	31	MTRNR2L12	MT-RNR2 like 12 [Source:HGNC Symbol;Acc:HGNC:37169]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000269035	0	0	0	0	0	0	0	0	0	0	0	0	TMEM221	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000269058	0.038	0	0.103	0	0	0	1	0	2	0	0	0	CALR3	calreticulin 3 [Source:HGNC Symbol;Acc:HGNC:20407]	-	-	-	-	GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane	GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0044183//protein folding chaperone;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding	GO:0006457//protein folding;GO:0007283//spermatogenesis;GO:0008150//biological_process;GO:0030154//cell differentiation;GO:0030433//ubiquitin-dependent ERAD pathway	--
ENSG00000269067	0	0	0	0	0	0	0	0	0	0	0	0	ZNF728	zinc finger protein 728 [Source:HGNC Symbol;Acc:HGNC:32463]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000269095	0	0	0	0	0	0	0	0	0	0	0	0	NR2F6	novel protein	-	-	-	-	-	-	-	--
ENSG00000269096	0	0	0	0	0	0	0	0	0	0	0	0	CT45A3	cancer/testis antigen family 45 member A3 [Source:HGNC Symbol;Acc:HGNC:33268]	-	-	-	-	GO:0032039//integrator complex	GO:0005515//protein binding	GO:0034472//snRNA 3'-end processing	--
ENSG00000269113	0.211	0.172	0.182	0.536	0.417	0.335	33	27	21	62	55	38	TRABD2B	TraB domain containing 2B [Source:HGNC Symbol;Acc:HGNC:44200]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031301//integral component of organelle membrane	GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0017147//Wnt-protein binding;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0031334//positive regulation of protein-containing complex assembly;GO:1904808//positive regulation of protein oxidation	--
ENSG00000269179	0	0	0	0	0	0	0	0	0	0	0	0	SIGLEC11	novel protein	-	-	-	-	GO:0005886//plasma membrane	GO:0033691//sialic acid binding	GO:0007155//cell adhesion	--
ENSG00000269190	15.715	17.989	14.94	13.29	14.07	14.869	578	646	382	352	443	388	FBXO17	F-box protein 17 [Source:HGNC Symbol;Acc:HGNC:18754]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex	GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity	GO:0006516//glycoprotein catabolic process;GO:0016567//protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process	--
ENSG00000269226	1.662	1.301	1.656	1.414	1.526	1.072	71.33	62	58	49.68	53.92	37	TMSB15B	thymosin beta 15B [Source:NCBI gene (formerly Entrezgene);Acc:286527]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0003785//actin monomer binding	GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers	--
ENSG00000269237	0	0	0	0	0	0	0	0	0	0	0	0	ZNF430	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269242	0	0	0.646	0.156	0.394	0	0	0	8.29	2.01	5.79	0	MAN2B1	novel transcript	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K12311;K12311	GO:0005764//lysosome	GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0030246//carbohydrate binding	GO:0005975//carbohydrate metabolic process	--
ENSG00000269307	0	0	0	0	0	0	0	0	0	0	0	0	BABAM1	novel transcript	Genetic Information Processing	Replication and repair	ko03440//Homologous recombination	K20776	-	-	-	--
ENSG00000269313	1.376	1.7	1.303	3.853	1.926	1.211	33	39	27	63	40	28	MAGIX	"MAGI family member, X-linked [Source:HGNC Symbol;Acc:HGNC:30006]"	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000269335	8.1	9.646	9.855	10.691	7.856	7.648	312	328	251	282	248	201	IKBKG	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma [Source:HGNC Symbol;Acc:HGNC:5961]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Infectious disease: viral;Endocrine and metabolic disease;Cell growth and death;Cardiovascular disease;Development and regeneration;Immune disease;Signal transduction;Immune system;Infectious disease: parasitic;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: specific types;Immune system;Cancer: overview;Immune system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: specific types;Immune system;Infectious disease: bacterial;Endocrine system;Immune system;Drug resistance: antineoplastic	ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko04010//MAPK signaling pathway;ko05169//Epstein-Barr virus infection;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05203//Viral carcinogenesis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko04662//B cell receptor signaling pathway;ko05162//Measles;ko04936//Alcoholic liver disease;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04380//Osteoclast differentiation;ko05340//Primary immunodeficiency;ko04668//TNF signaling pathway;ko04659//Th17 cell differentiation;ko05145//Toxoplasmosis;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05215//Prostate cancer;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04657//IL-17 signaling pathway;ko05222//Small cell lung cancer;ko05212//Pancreatic cancer;ko05220//Chronic myeloid leukemia;ko05221//Acute myeloid leukemia;ko04622//RIG-I-like receptor signaling pathway;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04920//Adipocytokine signaling pathway;ko04623//Cytosolic DNA-sensing pathway;ko01523//Antifolate resistance	K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210;K07210	GO:0000151//ubiquitin ligase complex;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0008385//IkappaB kinase complex;GO:0032991//protein-containing complex;GO:0072686//mitotic spindle	GO:0005515//protein binding;GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:1990450//linear polyubiquitin binding;GO:1990459//transferrin receptor binding	GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009615//response to virus;GO:0016239//positive regulation of macroautophagy;GO:0016310//phosphorylation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043276//anoikis;GO:0045087//innate immune response;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050852//T cell receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051650//establishment of vesicle localization;GO:0065003//protein-containing complex assembly;GO:1901215//negative regulation of neuron death	--
ENSG00000269343	1.482	1.182	1.765	0.935	1.327	1.881	139.26	120.29	109.97	60	91.03	105.56	ZNF587B	zinc finger protein 587B [Source:HGNC Symbol;Acc:HGNC:37142]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000269403	0.101	0	0	0	0.222	0	1.16	0	0	0	2.14	0	CLDND2	novel protein	-	-	-	-	-	-	-	--
ENSG00000269404	1.908	0.771	0.406	0.322	0.573	0.138	32	27	12	6	9	3	SPIB	Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription by RNA polymerase II"	ETS
ENSG00000269405	0.034	0	0	0	0	0	1.5	0	0	0	0	0	NXF2	nuclear RNA export factor 2 [Source:HGNC Symbol;Acc:HGNC:8072]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14284;K14284;K14284;K14284;K14284;K14284	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042272//nuclear RNA export factor complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0050658//RNA transport;GO:0051028//mRNA transport	--
ENSG00000269433	0	0	0	0	0	0	0	0	0	0	0	0	OPN1MW3	"opsin 1, medium wave sensitive 3 [Source:HGNC Symbol;Acc:HGNC:51831]"	-	-	-	-	GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0008020//G protein-coupled photoreceptor activity;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0009584//detection of visible light;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus;GO:0071482//cellular response to light stimulus	--
ENSG00000269437	0.034	0	0	0	0	0	1.5	0	0	0	0	0	NXF2B	nuclear RNA export factor 2B [Source:HGNC Symbol;Acc:HGNC:23984]	Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Translation;Translation;Translation	ko05168//Herpes simplex virus 1 infection;ko05014//Amyotrophic lateral sclerosis;ko05164//Influenza A;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway;ko03008//Ribosome biogenesis in eukaryotes	K14284;K14284;K14284;K14284;K14284;K14284	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0042272//nuclear RNA export factor complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0050658//RNA transport;GO:0051028//mRNA transport	--
ENSG00000269466	0	0	0	0	0	0	0	0	0	0	0	0	H3Y1	H3.Y histone 1 [Source:HGNC Symbol;Acc:HGNC:43735]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0031492//nucleosomal DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000269469	0	0	0	0	0	0	0	0	0	0	0	0	ALDH16A1	novel protein	-	-	-	-	-	-	-	--
ENSG00000269476	0	0	0	0	0	0.362	0	0	0	0	0	5.57	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000269502	3.318	2.282	4.67	5.362	3.984	3.157	91.04	64.99	97.52	112.28	95.3	64.95	DMRTC1	DMRT like family C1 [Source:HGNC Symbol;Acc:HGNC:13910]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	-	"GO:0006355//regulation of transcription, DNA-templated"	Others
ENSG00000269526	0	0	0	0	0	0	0	0	0	0	0	0	ERVV-1	"endogenous retrovirus group V member 1, envelope [Source:HGNC Symbol;Acc:HGNC:26501]"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000269533	0	0	0.228	0	0.201	0	0	0	1.87	0	1.89	0	ZNF17	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269547	0	0	0	0	0	0	0	0	0	0	0	0	SARS2	novel protein	Genetic Information Processing	Translation	ko00970//Aminoacyl-tRNA biosynthesis	K01875	GO:0005739//mitochondrion	GO:0000049//tRNA binding;GO:0000166//nucleotide binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0004828//serine-tRNA ligase activity;GO:0005524//ATP binding;GO:0016874//ligase activity	GO:0006418//tRNA aminoacylation for protein translation;GO:0006434//seryl-tRNA aminoacylation;GO:0070158//mitochondrial seryl-tRNA aminoacylation;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process	--
ENSG00000269556	11.904	10.523	10.075	10.649	10.021	10.389	520	541	382	426	456	375	TMEM185A	transmembrane protein 185A [Source:HGNC Symbol;Acc:HGNC:17125]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0042995//cell projection	GO:0005515//protein binding	-	--
ENSG00000269586	0	0	0	0	0	0	0	0	0	0	0	0	CT45A10	cancer/testis antigen family 45 member A10 [Source:HGNC Symbol;Acc:HGNC:51263]	-	-	-	-	GO:0032039//integrator complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:0034472//snRNA 3'-end processing	--
ENSG00000269590	0	0	0	0	0	0	0	0	0	0	0	0	MAN2B1	novel protein	Cellular Processes;Metabolism	Transport and catabolism;Glycan biosynthesis and metabolism	ko04142//Lysosome;ko00511//Other glycan degradation	K12311;K12311	GO:0005764//lysosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane	GO:0003824//catalytic activity;GO:0004559//alpha-mannosidase activity;GO:0044183//protein folding chaperone	GO:0005975//carbohydrate metabolic process;GO:0006013//mannose metabolic process;GO:0006457//protein folding;GO:0045048//protein insertion into ER membrane	--
ENSG00000269693	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	zf-C2H2
ENSG00000269699	0	0	0	0	0	0	0	0	0	0	0	0	ZIM2	zinc finger imprinted 2 [Source:HGNC Symbol;Acc:HGNC:12875]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000269711	0	0	0	0	0	0	0	0	0	0	0	0	MCEMP1	novel protein	-	-	-	-	-	-	-	--
ENSG00000269713	27.78	29.146	29.545	16.898	25.717	23.886	1053.43	987.16	755.31	519.86	739.23	708.71	NBPF9	NBPF member 9 [Source:HGNC Symbol;Acc:HGNC:31991]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000269720	0	0	0	0	0	0	0	0	0	0	0	0	CCDC194	coiled-coil domain containing 194 [Source:HGNC Symbol;Acc:HGNC:53438]	-	-	-	-	-	-	-	--
ENSG00000269741	0	0	0	0	0	0	0	0	0	0	0	0	KLK9	novel transcript	-	-	-	-	GO:0030141//secretory granule	GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000269743	0.016	0.085	0.042	0.084	0.129	0.085	2	11	4	8	14	8	SLC25A53	solute carrier family 25 member 53 [Source:HGNC Symbol;Acc:HGNC:31894]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000269755	0.12	0	0	0	0	0	1.46	0	0	0	0	0	ZNF709	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269791	0	0	0	0	0	0	0	0	0	0	0	0	SSX4B	SSX family member 4B [Source:HGNC Symbol;Acc:HGNC:16880]	Human Diseases	Cancer: overview	ko05202//Transcriptional misregulation in cancer	K15624	GO:0005634//nucleus	GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269825	0.428	0.203	0.245	0.26	0.322	0.249	37.81	18	16	17	24	16	ZNF816	novel zinc finger protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000269855	0.068	0	0	0	0	0.047	2	0	0	0	0	1	RNF225	ring finger protein 225 [Source:HGNC Symbol;Acc:HGNC:51249]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000269858	23.208	25.164	26.744	28.893	24.922	26.487	1016.25	1055.46	866	936.12	921	800.21	EGLN2	egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660]	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09592;K09592;K09592	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	"GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0008198//ferrous iron binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//2-oxoglutarate-dependent dioxygenase activity;GO:0019826//oxygen sensor activity;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	GO:0001558//regulation of cell growth;GO:0001666//response to hypoxia;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0043523//regulation of neuron apoptotic process;GO:0045454//cell redox homeostasis;GO:0045732//positive regulation of protein catabolic process;GO:0071456//cellular response to hypoxia	--
ENSG00000269891	0	0	0	0	0	0	0	0	0	0	0	0	ARHGAP19-SLIT1	ARHGAP19-SLIT1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48348]	-	-	-	-	-	-	-	--
ENSG00000269897	2.968	3.706	3.093	0.355	2.755	1.637	45.87	57.57	35.3	4.06	41.51	18.4	COMMD3-BMI1	COMMD3-BMI1 readthrough [Source:HGNC Symbol;Acc:HGNC:48326]	Human Diseases;Human Diseases;Cellular Processes	Cancer: overview;Cancer: overview;Cellular community - eukaryotes	ko05202//Transcriptional misregulation in cancer;ko05206//MicroRNAs in cancer;ko04550//Signaling pathways regulating pluripotency of stem cells	K11459;K11459;K11459	GO:0005634//nucleus;GO:0005829//cytosol;GO:0016604//nuclear body	GO:0046872//metal ion binding	GO:0006814//sodium ion transport	--
ENSG00000269955	10.716	4.67	6.246	6.855	5.533	4.09	369.19	161.72	158.92	174.93	161.05	102.53	FMC1-LUC7L2	FMC1-LUC7L2 readthrough [Source:HGNC Symbol;Acc:HGNC:44671]	-	-	-	-	GO:0005685//U1 snRNP	GO:0003729//mRNA binding	GO:0006376//mRNA splice site selection	--
ENSG00000269964	0.182	0.156	0.136	0.066	0.093	0.137	20	16	11	5	8	9	MEI4	meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638]	-	-	-	-	GO:0000800//lateral element;GO:0005694//chromosome	GO:0005515//protein binding	GO:0006310//DNA recombination;GO:0007129//homologous chromosome pairing at meiosis;GO:0007283//spermatogenesis;GO:0042138//meiotic DNA double-strand break formation;GO:0048477//oogenesis;GO:0051321//meiotic cell cycle	--
ENSG00000270011	1.053	1.023	0.905	1.854	0.916	0.722	23.32	17.78	20.95	20.4	18.83	15.77	ZNF559-ZNF177	ZNF559-ZNF177 readthrough [Source:HGNC Symbol;Acc:HGNC:42964]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	zf-C2H2
ENSG00000270099	0	0	0	0	0	0	0	0	0	0	0	0	ENTPD1	novel transcript	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Infectious disease: viral;Nucleotide metabolism;Nucleotide metabolism	ko01100//Metabolic pathways;ko05169//Epstein-Barr virus infection;ko00230//Purine metabolism;ko00240//Pyrimidine metabolism	K01510;K01510;K01510;K01510	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0004382//guanosine-diphosphatase activity;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0045134//uridine-diphosphatase activity	GO:0009134//nucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process	--
ENSG00000270106	0.293	0.222	0.056	0	0	0	19.84	15.24	2.85	0	0	0	TSNAX-DISC1	TSNAX-DISC1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49177]	-	-	-	-	-	GO:0043565//sequence-specific DNA binding	-	--
ENSG00000270136	0.076	0.073	0.195	0	0	0	1.29	1.24	2.45	0	0	0	MICOS10-NBL1	MICOS10-NBL1 readthrough [Source:HGNC Symbol;Acc:HGNC:48338]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0061617//MICOS complex	-	-	--
ENSG00000270149	7.268	7.013	6.068	6.26	6.479	5.889	277.75	306.45	194.83	187.22	237.97	186.28	--	"novel transcript, TSTD1 - F11R readthrough"	-	-	-	-	-	-	-	--
ENSG00000270170	6.761	7.222	6.678	6.733	8.265	7.007	122	131	89	90	126	92	NCBP2AS2	NCBP2 antisense 2 (head to head) [Source:HGNC Symbol;Acc:HGNC:25121]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000270181	0.143	0.297	0	0	0.535	0	15.4	32.2	0	0	48.66	0	BIVM-ERCC5	BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGNC:43690]	Genetic Information Processing	Replication and repair	ko03420//Nucleotide excision repair	K10846	GO:0005634//nucleus	"GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0003824//catalytic activity;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0016787//hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0046872//metal ion binding"	GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006807//nitrogen compound metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0044238//primary metabolic process;GO:0044260//cellular macromolecule metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis	--
ENSG00000270185	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1OR15-1B	immunoglobulin heavy diversity 1/OR15-1B (non-functional) [Source:HGNC Symbol;Acc:HGNC:5488]	-	-	-	-	-	-	-	--
ENSG00000270188	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L11	MT-RNR2 like 11 [Source:HGNC Symbol;Acc:HGNC:37168]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000270249	0	0.219	0.32	0.344	0	0.698	0	4.15	4.47	4.81	0	9.6	RASA4B	novel protein	Environmental Information Processing	Signal transduction	ko04014//Ras signaling pathway	K17630	-	GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction"	--
ENSG00000270276	1.601	0.26	0.615	0.719	0	3.677	19.16	9.18	3.73	14.96	0	41.04	H4C15	H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000270299	0	0	0	0	0	0	0	0	0	0	0	0	SCRT2	novel protein	-	-	-	-	-	-	-	--
ENSG00000270316	0	0	0	0	0	0	0	0	0	0	0	0	BORCS7-ASMT	BORCS7-ASMT readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49183]	-	-	-	-	GO:0005764//lysosome;GO:0016020//membrane	-	-	--
ENSG00000270339	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4H	peptidylprolyl isomerase A like 4H [Source:HGNC Symbol;Acc:HGNC:53889]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000270379	0	0	0	0	0	0	0	0	0	0	0	0	HEATR9	HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548]	-	-	-	-	-	GO:0005515//protein binding	GO:0002244//hematopoietic progenitor cell differentiation	--
ENSG00000270394	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L13	MT-RNR2 like 13 [Source:HGNC Symbol;Acc:HGNC:37170]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000270451	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000270467	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-12	immunoglobulin heavy variable 3/OR16-12 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5636]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000270472	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-9	immunoglobulin heavy variable 3/OR16-9 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5644]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	-	-	-	--
ENSG00000270505	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1OR15-1	immunoglobulin heavy variable 1/OR15-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5563]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000270550	0	0	0	0	0.265	0	0	0	0	0	2	0	IGHV3-30	immunoglobulin heavy variable 3-30 [Source:HGNC Symbol;Acc:HGNC:5591]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000270601	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF5	PRAME family member 5 [Source:HGNC Symbol;Acc:HGNC:27995]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000270617	0.334	0.097	0	0	0.238	0.628	5.51	1.6	0	0	3.32	7.53	URGCP-MRPS24	URGCP-MRPS24 readthrough [Source:HGNC Symbol;Acc:HGNC:49188]	-	-	-	-	-	-	-	--
ENSG00000270629	21.262	17.613	18.313	12.502	14.96	14.351	2559.26	2255.98	1723.35	1157.57	1642.87	1257.21	NBPF14	NBPF member 14 [Source:HGNC Symbol;Acc:HGNC:25232]	-	-	-	-	-	-	-	--
ENSG00000270647	31.595	30.685	28.784	26.364	28.362	28.08	1198	1136	821	765	864	815	TAF15	TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547]	Human Diseases;Genetic Information Processing	Cancer: overview;Transcription	ko05202//Transcriptional misregulation in cancer;ko03022//Basal transcription factors	K14651;K14651	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003712//transcription coregulator activity;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048255//mRNA stabilization"	--
ENSG00000270672	0	0	0	0	0	0	0	0	0	0	0	0	MTRNR2L6	MT-RNR2 like 6 [Source:HGNC Symbol;Acc:HGNC:37163]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm	GO:0048019//receptor antagonist activity	GO:1900118//negative regulation of execution phase of apoptosis;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000270757	1.477	0.956	0.262	3.328	2.167	0	27.27	17.74	3.57	45.51	33.8	0	HSPE1-MOB4	HSPE1-MOB4 readthrough [Source:HGNC Symbol;Acc:HGNC:49184]	-	-	-	-	-	GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	GO:0006457//protein folding	--
ENSG00000270765	0	0.014	0	0.039	0.034	0.039	0	1	0	2	2	2	GAS2L2	growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846]	-	-	-	-	GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0035371//microtubule plus-end;GO:0036064//ciliary basal body;GO:0042995//cell projection	GO:0001965//G-protein alpha-subunit binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal anchor activity;GO:0051015//actin filament binding	GO:0001578//microtubule bundle formation;GO:0007026//negative regulation of microtubule depolymerization;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0045745//positive regulation of G protein-coupled receptor signaling pathway;GO:0051764//actin crosslink formation;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:1904825//protein localization to microtubule plus-end	--
ENSG00000270800	1.312	1.215	0.65	0.677	0.995	0.812	79.23	69.12	29	30.27	50.75	35.66	RPS10-NUDT3	RPS10-NUDT3 readthrough [Source:HGNC Symbol;Acc:HGNC:49181]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02947;K02947	GO:0005829//cytosol	GO:0016787//hydrolase activity	-	--
ENSG00000270806	0	0	0	0	0	0	0	0	0	0	0	0	C17orf50	chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000270824	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5OR15-5B	immunoglobulin heavy diversity 5/OR15-5B (non-functional) [Source:HGNC Symbol;Acc:HGNC:5513]	-	-	-	-	-	-	-	--
ENSG00000270882	2.457	0.956	3.841	1.12	1.771	2.873	36.84	30.82	52.27	22.04	47	25.96	H4C14	H4 clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4794]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000270885	7.123	7.161	6.985	7.855	7.952	9.542	475	480	344	388	448	463	RASL10B	RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0016787//hydrolase activity	GO:0003050//regulation of systemic arterial blood pressure by atrial natriuretic peptide;GO:0090277//positive regulation of peptide hormone secretion	--
ENSG00000270946	0	0	0	0	0	0	0	0	0	0	0	0	CT45A9	cancer/testis antigen family 45 member A9 [Source:HGNC Symbol;Acc:HGNC:51262]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000270961	0	0	0	0	0	0	0	0	0	0	0	0	IGHD5OR15-5A	immunoglobulin heavy diversity 5/OR15-5A (non-functional) [Source:HGNC Symbol;Acc:HGNC:5512]	-	-	-	-	-	-	-	--
ENSG00000271079	0.473	0.378	0.704	0.298	0.339	0.776	25.4	20.38	27.9	11.85	15.36	30.31	CTAGE15	CTAGE family member 15 [Source:HGNC Symbol;Acc:HGNC:37295]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000271092	1.546	1.245	1.437	0.773	1.06	1.648	47.81	36.62	30.47	17.7	27.7	37.08	TLCD4-RWDD3	TLCD4-RWDD3 readthrough [Source:HGNC Symbol;Acc:HGNC:49388]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000271130	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-8	immunoglobulin heavy variable 3/OR16-8 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5643]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000271178	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3OR16-13	immunoglobulin heavy variable 3/OR16-13 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5637]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000271271	0	0	0	0	0	0	0	0	0	0	0	0	UGT2A2	UDP glucuronosyltransferase family 2 member A2 [Source:HGNC Symbol;Acc:HGNC:28183]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005575//cellular_component;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0006629//lipid metabolic process;GO:0008206//bile acid metabolic process;GO:0052695//cellular glucuronidation	--
ENSG00000271303	13.159	13.376	14.925	14.521	14.469	16.775	690	705	578	564	641	640	SRXN1	sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	"GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0032542//sulfiredoxin activity"	GO:0006979//response to oxidative stress;GO:0034599//cellular response to oxidative stress;GO:0098869//cellular oxidant detoxification	--
ENSG00000271317	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000271321	0	0	0	0	0	0	0	0	0	0	0	0	CTAGE6	CTAGE family member 6 [Source:HGNC Symbol;Acc:HGNC:28644]	-	-	-	-	GO:0005575//cellular_component;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0008150//biological_process;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000271336	0	0	0	0	0	0	0	0	0	0	0	0	IGHD1OR15-1A	immunoglobulin heavy diversity 1/OR15-1A (non-functional) [Source:HGNC Symbol;Acc:HGNC:5487]	-	-	-	-	-	-	-	--
ENSG00000271383	30.084	25.436	27.26	16.594	25.461	21.102	1958.99	1682.31	1331.61	818.49	1378.74	1064.83	NBPF19	NBPF member 19 [Source:HGNC Symbol;Acc:HGNC:31999]	-	-	-	-	GO:0005737//cytoplasm	-	-	--
ENSG00000271425	5.222	4.554	5.046	3.505	4.302	3.105	1366.95	1163.51	973.12	582.3	955.78	603.44	NBPF10	NBPF member 10 [Source:HGNC Symbol;Acc:HGNC:31992]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000271447	0.864	0.931	0.653	1.998	2.936	1.56	29	34	18	66	82	50	MMP28	matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031012//extracellular matrix;GO:0062023//collagen-containing extracellular matrix	GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0010760//negative regulation of macrophage chemotaxis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process	--
ENSG00000271449	0	0	0	0	0	0	0	0	0	0	0	0	CT45A2	cancer/testis antigen family 45 member A2 [Source:HGNC Symbol;Acc:HGNC:28400]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000271503	0.04	0	0	0.107	0.264	0.101	1	0	0	2	6	1	CCL5	C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632]	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems	Infectious disease: viral;Signaling molecules and interaction;Neurodegenerative disease;Infectious disease: bacterial;Infectious disease: viral;Cardiovascular disease;Immune system;Immune system;Infectious disease: viral;Immune disease;Signal transduction;Infectious disease: parasitic;Immune system;Signaling molecules and interaction;Infectious disease: bacterial;Immune system	ko05168//Herpes simplex virus 1 infection;ko04060//Cytokine-cytokine receptor interaction;ko05020//Prion disease;ko05131//Shigellosis;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko04621//NOD-like receptor signaling pathway;ko05164//Influenza A;ko05323//Rheumatoid arthritis;ko04668//TNF signaling pathway;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04623//Cytosolic DNA-sensing pathway	K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499;K12499	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004672//protein kinase activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0016004//phospholipase activator activity;GO:0030298//receptor signaling protein tyrosine kinase activator activity;GO:0031726//CCR1 chemokine receptor binding;GO:0031729//CCR4 chemokine receptor binding;GO:0031730//CCR5 chemokine receptor binding;GO:0042056//chemoattractant activity;GO:0042379//chemokine receptor binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043621//protein self-association;GO:0046817//chemokine receptor antagonist activity;GO:0048020//CCR chemokine receptor binding	GO:0000165//MAPK cascade;GO:0002407//dendritic cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0002676//regulation of chronic inflammatory response;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007159//leukocyte cell-cell adhesion;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0009636//response to toxic substance;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0010759//positive regulation of macrophage chemotaxis;GO:0010820//positive regulation of T cell chemotaxis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030335//positive regulation of cell migration;GO:0030593//neutrophil chemotaxis;GO:0031328//positive regulation of cellular biosynthetic process;GO:0031584//activation of phospholipase D activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0042102//positive regulation of T cell proliferation;GO:0042119//neutrophil activation;GO:0042327//positive regulation of phosphorylation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043491//protein kinase B signaling;GO:0043547//positive regulation of GTPase activity;GO:0043922//negative regulation by host of viral transcription;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045070//positive regulation of viral genome replication;GO:0045071//negative regulation of viral genome replication;GO:0045089//positive regulation of innate immune response;GO:0045744//negative regulation of G protein-coupled receptor signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0045948//positive regulation of translational initiation;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048245//eosinophil chemotaxis;GO:0048246//macrophage chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050796//regulation of insulin secretion;GO:0050863//regulation of T cell activation;GO:0050918//positive chemotaxis;GO:0051928//positive regulation of calcium ion transport;GO:0060326//cell chemotaxis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0070098//chemokine-mediated signaling pathway;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0070233//negative regulation of T cell apoptotic process;GO:0070234//positive regulation of T cell apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0090026//positive regulation of monocyte chemotaxis;GO:0098586//cellular response to virus;GO:1901214//regulation of neuron death;GO:2000406//positive regulation of T cell migration;GO:2000503//positive regulation of natural killer cell chemotaxis	--
ENSG00000271567	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4E	peptidylprolyl isomerase A like 4E [Source:HGNC Symbol;Acc:HGNC:33997]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000271601	11.307	11.55	11.678	10.861	10.409	11.522	936	961	714	666	728	694	LIX1L	limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715]	-	-	-	-	GO:0005575//cellular_component;GO:0005737//cytoplasm	GO:0003674//molecular_function	GO:0008150//biological_process;GO:0097352//autophagosome maturation	--
ENSG00000271605	0	0.08	0	0.369	0.191	0.166	0	1	0	4	2	3	MILR1	mast cell immunoglobulin like receptor 1 [Source:HGNC Symbol;Acc:HGNC:27570]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0007166//cell surface receptor signaling pathway;GO:0033004//negative regulation of mast cell activation;GO:0043303//mast cell degranulation;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules	--
ENSG00000271698	0	0.03	0.123	0.041	0	0	0	1	3	1	0	0	FBXL6	novel transcript	-	-	-	-	-	-	-	--
ENSG00000271723	0.588	0.298	0.215	0.217	0.528	0.16	72	35.5	19.7	19.27	55.33	14.71	MROH7-TTC4	MROH7-TTC4 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49180]	-	-	-	-	-	-	-	--
ENSG00000271741	1.021	0.581	0.8	0.975	0.532	1.115	65.63	37.55	37.97	46.41	28.89	52.13	ZMYM6	"novel transcript, ZMYM6-ZMYM6NB readthrough"	-	-	-	-	-	-	-	--
ENSG00000271793	0.284	0.222	0.168	0.136	0.115	0.283	23.26	18.31	10.19	8.26	7.98	16.88	SYNCRIP	"novel protein, SYNCRIP-SNX14 readthrough"	-	-	-	-	-	-	-	--
ENSG00000271810	0	0	0	0	0	0	0	0	0	0	0	0	PPM1J	"novel protein, PPM1J-RHOC readthrough"	-	-	-	-	GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0031410//cytoplasmic vesicle;GO:0042995//cell projection;GO:0043005//neuron projection	GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0016791//phosphatase activity;GO:0019901//protein kinase binding	GO:0007015//actin filament organization;GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0016311//dephosphorylation;GO:0016477//cell migration;GO:0030865//cortical cytoskeleton organization;GO:0032956//regulation of actin cytoskeleton organization	--
ENSG00000271824	0	0.028	0	0	0	0	0	1	0	0	0	0	SMIM32	small integral membrane protein 32 [Source:HGNC Symbol;Acc:HGNC:53640]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000271949	0	0	0	0	0	0	0	0	0	0	0	0	LRRC8C	"novel transcript, LRRC8C-LRRC8D readthrough"	-	-	-	-	-	-	-	--
ENSG00000272031	0.508	0.545	0.633	1.821	0.712	0.937	38	41	35	55	45	51	ANKRD34A	ankyrin repeat domain 34A [Source:HGNC Symbol;Acc:HGNC:27639]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000272047	12.591	13.172	12.569	12.373	10.531	9.382	312	301	189	191	203	154	GTF2H5	general transcription factor IIH subunit 5 [Source:HGNC Symbol;Acc:HGNC:21157]	Genetic Information Processing;Genetic Information Processing	Transcription;Replication and repair	ko03022//Basal transcription factors;ko03420//Nucleotide excision repair	K10845;K10845	GO:0000439//transcription factor TFIIH core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0005675//transcription factor TFIIH holo complex;GO:0005730//nucleolus;GO:0005737//cytoplasm	GO:0005515//protein binding	"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006281//DNA repair;GO:0006289//nucleotide-excision repair;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006366//transcription by RNA polymerase II;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:0071480//cellular response to gamma radiation"	--
ENSG00000272104	0	0	0	0	0	0	0	0	0	0	0	0	CYB561D2	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0140575//transmembrane monodehydroascorbate reductase activity	-	--
ENSG00000272162	0	0	0	0	0	0	0	0	0	0	0	0	TMEM14DP	"novel transcript, TMEM14B-SYCP2L readthrough"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000272297	0	0	0	0	0	0	0	0	0	0	0	0	MTNR1A	novel protein	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Environmental adaptation	ko04080//Neuroactive ligand-receptor interaction;ko04713//Circadian entrainment	K04285;K04285	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007623//circadian rhythm	--
ENSG00000272305	0.158	0	0	0.085	0	0	2.26	0	0	1	0	0	RFT1	novel transcript	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0034203//glycolipid translocation	--
ENSG00000272325	10.283	9.754	11.252	9.876	10.153	10.109	2111.66	2013.23	1706.44	1502.21	1761.5	1510.32	NUDT3	nudix hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:8050]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0000298//endopolyphosphatase activity;GO:0005515//protein binding;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0016787//hydrolase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872//metal ion binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity	GO:0007267//cell-cell signaling;GO:0015961//diadenosine polyphosphate catabolic process;GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0071544//diphosphoinositol polyphosphate catabolic process;GO:0110154//RNA decapping;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	--
ENSG00000272333	6.338	6.78	8.456	8.249	9.592	7.589	791	916	661	640	879	698	KMT2B	lysine methyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:15840]	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K14959;K14959	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031981//nuclear lumen;GO:0035097//histone methyltransferase complex;GO:0044665//MLL1/2 complex	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0045322//unmethylated CpG binding;GO:0046872//metal ion binding	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0032259//methylation;GO:0044648//histone H3-K4 dimethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0097692//histone H3-K4 monomethylation"	--
ENSG00000272391	20.999	15.803	16.921	16.899	18.165	22.778	1590.82	1592.01	1235.61	1248.06	1500.65	1298.8	POM121C	POM121 transmembrane nucleoporin C [Source:HGNC Symbol;Acc:HGNC:34005]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Translation	ko05014//Amyotrophic lateral sclerosis;ko03013//Nucleocytoplasmic transport	K14316;K14316	GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane	GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0017056//structural constituent of nuclear pore	GO:0006405//RNA export from nucleus;GO:0006606//protein import into nucleus;GO:0015031//protein transport;GO:0051028//mRNA transport	--
ENSG00000272395	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000272398	11.101	11.771	10.493	4.551	5.912	3.446	517	521	318	144	218	114	CD24	CD24 molecule [Source:HGNC Symbol;Acc:HGNC:1645]	Organismal Systems	Immune system	ko04640//Hematopoietic cell lineage	K06469	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045121//membrane raft	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030296//protein tyrosine kinase activator activity	GO:0001666//response to hypoxia;GO:0001775//cell activation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016055//Wnt signaling pathway;GO:0016477//cell migration;GO:0030856//regulation of epithelial cell differentiation;GO:0031295//T cell costimulation;GO:0032597//B cell receptor transport into membrane raft;GO:0032600//chemokine receptor transport out of membrane raft;GO:0032913//negative regulation of transforming growth factor beta3 production;GO:0042104//positive regulation of activated T cell proliferation;GO:0042325//regulation of phosphorylation;GO:0042632//cholesterol homeostasis;GO:0043406//positive regulation of MAP kinase activity;GO:0043408//regulation of MAPK cascade;GO:0043627//response to estrogen;GO:0045730//respiratory burst;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072139//glomerular parietal epithelial cell differentiation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0098609//cell-cell adhesion;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation	--
ENSG00000272410	6.31	5.289	7.069	9.441	5.202	6.697	331.53	279.43	257.95	358.08	223.18	248.94	TATDN2	novel protein	-	-	-	-	-	"GO:0016788//hydrolase activity, acting on ester bonds"	-	--
ENSG00000272414	0.124	0.403	0	0.593	0.217	0	3.82	12.34	0	16.74	5.64	0	FAM47E-STBD1	FAM47E-STBD1 readthrough [Source:HGNC Symbol;Acc:HGNC:44667]	-	-	-	-	-	-	-	--
ENSG00000272442	0	0.025	0	0.019	0	0	0	1.83	0	1	0	0	TMEM151B	"novel protein, TMEM151B-SPATS1 readtrough"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000272514	1.201	1.232	1.094	0.434	0.414	0.54	52	56.69	37	11	16	18	CFAP206	cilia and flagella associated protein 206 [Source:HGNC Symbol;Acc:HGNC:21405]	-	-	-	-	GO:0001534//radial spoke;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0042995//cell projection;GO:0097649//A axonemal microtubule	GO:0005515//protein binding	GO:0003341//cilium movement;GO:0003356//regulation of cilium beat frequency;GO:0007288//sperm axoneme assembly;GO:0030030//cell projection organization;GO:0035082//axoneme assembly;GO:1901317//regulation of flagellated sperm motility	--
ENSG00000272573	0.03	0.092	0.25	0	0	0.167	0.33	1	2	0	0	1.32	MUSTN1	"musculoskeletal, embryonic nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:22144]"	-	-	-	-	GO:0005634//nucleus	-	GO:0002062//chondrocyte differentiation;GO:0035988//chondrocyte proliferation;GO:0042246//tissue regeneration	--
ENSG00000272602	3.136	2.496	2.738	1.887	2.771	2.218	149	131.18	96	74	109	79	ZNF595	zinc finger protein 595 [Source:HGNC Symbol;Acc:HGNC:27196]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000272617	0	0	0.105	0	0	0.004	0	0	1.42	0	0	0.05	COG8	"novel protein, COG8-PDF readthrough"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0017119//Golgi transport complex	-	GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport	--
ENSG00000272636	4.144	4.122	5.04	5.862	6.401	5.607	521	521	468	546	680	513	DOC2B	double C2 domain beta [Source:HGNC Symbol;Acc:HGNC:2986]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031201//SNARE complex;GO:0045202//synapse;GO:0098793//presynapse	GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0019905//syntaxin binding;GO:0046872//metal ion binding	GO:0007268//chemical synaptic transmission;GO:0008104//protein localization;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0031340//positive regulation of vesicle fusion;GO:0032024//positive regulation of insulin secretion;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0061669//spontaneous neurotransmitter secretion	--
ENSG00000272647	0	0	0	0	0.138	0.064	0	0	0	0	2	0.8	ZNF655	novel protein	-	-	-	-	-	-	-	--
ENSG00000272674	0.75	0.797	0.425	0.363	1.009	0.716	55	43.8	25	21.44	42	22.92	PCDHB16	protocadherin beta 16 [Source:HGNC Symbol;Acc:HGNC:14546]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045202//synapse	GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	--
ENSG00000272741	0	0.12	0	0	0	0.431	0	1.77	0	0	0	4.6	TCTEX1D2	novel protein	-	-	-	-	-	-	-	--
ENSG00000272772	0	0	0.318	0	0	0	0	0	2.35	0	0	0	SKP1	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Genetic Information Processing;Genetic Information Processing;Cellular Processes;Cellular Processes;Environmental Information Processing;Organismal Systems;Environmental Information Processing	"Cancer: overview;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: viral;Signal transduction;Folding, sorting and degradation;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Signal transduction;Environmental adaptation;Signal transduction"	ko05200//Pathways in cancer;ko05132//Salmonella infection;ko05131//Shigellosis;ko05170//Human immunodeficiency virus 1 infection;ko04310//Wnt signaling pathway;ko04141//Protein processing in endoplasmic reticulum;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04350//TGF-beta signaling pathway;ko04710//Circadian rhythm;ko04341//Hedgehog signaling pathway - fly	K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094;K03094	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0097602//cullin family protein binding	GO:0006511//ubiquitin-dependent protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	--
ENSG00000272804	0	0	0	0	0	0	0	0	0	0	0	0	KRTAP10-7	keratin associated protein 10-7 [Source:HGNC Symbol;Acc:HGNC:22970]	-	-	-	-	GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament	GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000272822	0.339	0.11	0.14	0.274	0.239	0	6.61	2.15	2.01	3.96	3.94	0	ARF3	novel protein	Cellular Processes	Transport and catabolism	ko04144//Endocytosis	K07938	GO:0005886//plasma membrane	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000272886	5.409	5.025	4.902	4.456	6.172	5.756	616	561	445	379	517	414	DCP1A	decapping mRNA 1A [Source:HGNC Symbol;Acc:HGNC:18714]	Genetic Information Processing	"Folding, sorting and degradation"	ko03018//RNA degradation	K12610	GO:0000932//P-body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0043229//intracellular organelle	GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016787//hydrolase activity;GO:0019894//kinesin binding;GO:0042802//identical protein binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0043085//positive regulation of catalytic activity;GO:0110156//methylguanosine-cap decapping;GO:1903608//protein localization to cytoplasmic stress granule"	--
ENSG00000272896	0.264	0.066	0.356	0.267	0.359	0.09	4.03	1.01	4.01	3.01	4.62	1	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000272897	0	0	0	0	0	0	0	0	0	0	0	0	NFS1	novel protein	Metabolism;Metabolism;Genetic Information Processing	"Global and overview maps;Metabolism of cofactors and vitamins;Folding, sorting and degradation"	ko01100//Metabolic pathways;ko00730//Thiamine metabolism;ko04122//Sulfur relay system	K04487;K04487;K04487	GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol	GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding;GO:0031071//cysteine desulfurase activity	GO:0016226//iron-sulfur cluster assembly;GO:0044571//[2Fe-2S] cluster assembly	--
ENSG00000272899	0.72	0.494	0.605	0.553	0.353	0.58	58	40	36	33	24	34	ATP6V1FNB	ATP6V1F neighbor [Source:HGNC Symbol;Acc:HGNC:52392]	-	-	-	-	-	-	-	--
ENSG00000272916	0.136	0.524	0.16	0.503	0.287	0.289	16.4	41.58	14.3	35.46	29.25	25.36	NDST2	novel transcript	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00534//Glycosaminoglycan biosynthesis - heparan sulfate / heparin	K02577;K02577	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity	GO:0030210//heparin biosynthetic process;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000272921	8.322	7.452	10.752	12.037	7.144	8.263	141.2	127.09	134.73	151.28	102.4	102.01	DYRK4	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0018107//peptidyl-threonine phosphorylation	--
ENSG00000272968	0.431	0	0.13	0	0.257	0.149	8.94	0	2	0	4.45	2.25	RBAK-RBAKDN	RBAK-RBAKDN readthrough [Source:HGNC Symbol;Acc:HGNC:42971]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000272987	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000273003	0	0	0	0	0	0	0	0	0	0	0	0	ARL2-SNX15	ARL2-SNX15 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49197]	-	-	-	-	GO:0005815//microtubule organizing center	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005525//GTP binding	-	--
ENSG00000273025	0	0	0	0	0	0	0	0	0	0	0	0	CELF6	novel transcript	-	-	-	-	-	-	-	--
ENSG00000273045	1.791	2.16	2.693	2.527	2.771	2.001	60.44	67.78	65.89	62	79	49.13	C2orf15	chromosome 2 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:28436]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	-	--
ENSG00000273047	0	0	0	0	0	0	0	0	0	0	0	0	LIME1	"novel transcript, LIME1-SLC2A4RG readthrough"	-	-	-	-	GO:0019815//B cell receptor complex	GO:0019901//protein kinase binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043405//regulation of MAP kinase activity;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:1901222//regulation of NIK/NF-kappaB signaling	--
ENSG00000273049	0	0	0	0	0	0	0	0	0	0	0	0	HOXC10	"novel protein, readthrough between HOXC10 and HOXC5"	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009952//anterior/posterior pattern specification;GO:0048704//embryonic skeletal system morphogenesis"	Homeobox
ENSG00000273079	0.008	0.005	0.004	0.013	0.011	0.011	5	3	2	6	6	5	GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B [Source:HGNC Symbol;Acc:HGNC:4586]	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Signaling molecules and interaction;Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Immune disease;Substance dependence;Neurodegenerative disease;Nervous system;Nervous system;Environmental adaptation;Substance dependence;Nervous system;Substance dependence;Substance dependence	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko04080//Neuroactive ligand-receptor interaction;ko05016//Huntington disease;ko05020//Prion disease;ko04014//Ras signaling pathway;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko05017//Spinocerebellar ataxia;ko04728//Dopaminergic synapse;ko04724//Glutamatergic synapse;ko04713//Circadian entrainment;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko05030//Cocaine addiction;ko05033//Nicotine addiction	K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210;K05210	GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0017146//NMDA selective glutamate receptor complex;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0045202//synapse;GO:0045211//postsynaptic membrane;GO:0097060//synaptic membrane;GO:0098839//postsynaptic density membrane	GO:0001540//amyloid-beta binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004972//NMDA glutamate receptor activity;GO:0005216//ion channel activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015276//ligand-gated ion channel activity;GO:0016594//glycine binding;GO:0016595//glutamate binding;GO:0022849//glutamate-gated calcium ion channel activity;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	"GO:0006811//ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007420//brain development;GO:0007611//learning or memory;GO:0019722//calcium-mediated signaling;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0045471//response to ethanol;GO:0048167//regulation of synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0051290//protein heterotetramerization;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0060079//excitatory postsynaptic potential;GO:0060291//long-term synaptic potentiation;GO:0097553//calcium ion transmembrane import into cytosol;GO:0098655//cation transmembrane transport;GO:0098976//excitatory chemical synaptic transmission;GO:1901216//positive regulation of neuron death;GO:1902951//negative regulation of dendritic spine maintenance;GO:1904062//regulation of cation transmembrane transport;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:2001056//positive regulation of cysteine-type endopeptidase activity"	--
ENSG00000273085	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000273088	0.405	0.411	0	0.267	0.08	0.378	6.33	6.45	0	3.09	1.05	4.29	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000273111	0	0	0	0	0	0	0	0	0	0	0	0	LYPD4	LY6/PLAUR domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28659]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane;GO:0044853//plasma membrane raft;GO:0046658//anchored component of plasma membrane	-	-	--
ENSG00000273136	9.091	9.297	9.69	7.571	9.041	9.107	865.73	894.22	699	548.13	749.11	642.55	NBPF26	NBPF member 26 [Source:HGNC Symbol;Acc:HGNC:49571]	-	-	-	-	-	GO:0005509//calcium ion binding	-	--
ENSG00000273154	0.056	0.181	0.102	0.467	0.293	0.505	3.61	3.29	4.86	22.38	16.04	23.79	ZGPAT	"novel protein, ZGPAT-LIME1 readthrough"	-	-	-	-	GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0019815//B cell receptor complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003676//nucleic acid binding;GO:0003700//DNA-binding transcription factor activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding"	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043405//regulation of MAP kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:1901222//regulation of NIK/NF-kappaB signaling"	--
ENSG00000273155	0	0	0	0	0.63	0	0	0	0	0	7.38	0	MRPL30	novel LIPT1-MRPL30 readthrough	Genetic Information Processing	Translation	ko03010//Ribosome	K02907	GO:0015934//large ribosomal subunit	GO:0003735//structural constituent of ribosome	GO:0006412//translation	--
ENSG00000273167	0	0.115	0.257	0	0	0	0	9.97	16.38	0	0	0	SPATA13	novel transcript	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05769	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0050790//regulation of catalytic activity	--
ENSG00000273171	0	0	0	0	0	0	0	0	0	0	0	0	VTN	"novel protein, readthrough between VTN and SEBOX"	Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Immune system;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko04610//Complement and coagulation cascades;ko04512//ECM-receptor interaction	K06251;K06251;K06251;K06251;K06251;K06251	GO:0005615//extracellular space;GO:0062023//collagen-containing extracellular matrix	GO:0050840//extracellular matrix binding	GO:0007160//cell-matrix adhesion;GO:0033627//cell adhesion mediated by integrin	--
ENSG00000273173	1.066	0.18	0.423	0.823	0.973	0.38	15.01	2.44	4.52	8.52	12.18	4.18	SNURF	SNRPN upstream open reading frame [Source:HGNC Symbol;Acc:HGNC:11171]	-	-	-	-	GO:0005634//nucleus;GO:0016607//nuclear speck	GO:0003674//molecular_function	GO:0008150//biological_process	--
ENSG00000273213	0	0	0	0	0.022	0	0	0	0	0	1	0	H3-2	H3.2 histone (putative) [Source:HGNC Symbol;Acc:HGNC:32060]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000785//chromatin;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000273217	0	0	0.188	0	0.007	0.067	0	0	18.46	0	0.77	6.47	RAPGEF6	novel protein	Environmental Information Processing;Cellular Processes	Signal transduction;Cellular community - eukaryotes	ko04015//Rap1 signaling pathway;ko04530//Tight junction	K08020;K08020	GO:0005813//centrosome;GO:0005829//cytosol	GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000273238	0	0	0	0	0	0	0	0	0	0	0	0	TMEM271	transmembrane protein 271 [Source:HGNC Symbol;Acc:HGNC:53639]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000273259	1.688	1.645	1.734	0.63	0.891	1.398	107.37	105.16	81.49	29.69	47.88	64.7	SERPINA5	novel protein	-	-	-	-	-	-	-	--
ENSG00000273269	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Cancer: overview;Neurodegenerative disease;Sensory system;Neurodegenerative disease;Signal transduction;Neurodegenerative disease;Infectious disease: bacterial;Signal transduction;Infectious disease: viral;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Infectious disease: viral;Substance dependence;Signal transduction;Cell growth and death;Endocrine system;Circulatory system;Cell growth and death;Endocrine system;Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Nervous system;Nervous system;Immune system;Endocrine system;Environmental adaptation;Endocrine system;Sensory system;Signal transduction;Endocrine system;Digestive system;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Digestive system;Endocrine system;Substance dependence;Nervous system;Sensory system;Sensory system	ko05200//Pathways in cancer;ko05022//Pathways of neurodegeneration - multiple diseases;ko04740//Olfactory transduction;ko05010//Alzheimer disease;ko04020//Calcium signaling pathway;ko05012//Parkinson disease;ko05152//Tuberculosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04024//cAMP signaling pathway;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko05034//Alcoholism;ko04022//cGMP-PKG signaling pathway;ko04218//Cellular senescence;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04371//Apelin signaling pathway;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04270//Vascular smooth muscle contraction;ko04728//Dopaminergic synapse;ko04722//Neurotrophin signaling pathway;ko04625//C-type lectin receptor signaling pathway;ko04922//Glucagon signaling pathway;ko04713//Circadian entrainment;ko04916//Melanogenesis;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04912//GnRH signaling pathway;ko05133//Pertussis;ko05214//Glioma;ko04971//Gastric acid secretion;ko04924//Renin secretion;ko05031//Amphetamine addiction;ko04720//Long-term potentiation;ko04744//Phototransduction;ko04745//Phototransduction - fly	K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183;K02183	-	-	-	--
ENSG00000273274	0.258	0.174	0.137	0.183	0.209	0.145	68.62	46.47	27	36.02	47	28	ZBTB8B	zinc finger and BTB domain containing 8B [Source:HGNC Symbol;Acc:HGNC:37057]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	ZBTB
ENSG00000273291	0	0	0	0	0	0	0	0	0	0	0	0	KRBOX1	novel protein	-	-	-	-	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000273294	0	0	0	0	0	0	0	0	0	0	0	0	C1QTNF3-AMACR	C1QTNF3-AMACR readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49198]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000273331	0	0	0	0	0	0	0	0	0	0	0	0	TM4SF19-DYNLT2B	TM4SF19-DYNLT2B readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49190]	-	-	-	-	-	-	-	--
ENSG00000273398	0.457	0.323	0.489	0	0.436	0.336	21.86	15.53	17.27	0	17.62	11.69	PPP3R1	novel protein	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0046872//metal ion binding	GO:0050790//regulation of catalytic activity	--
ENSG00000273513	0.214	0.252	0	0	0.386	0	9.38	11.12	0	0	14.3	0	TBC1D3K	TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000273514	0	0	0	0	0	0	0	0	0	0	0	0	FOXD4L6	forkhead box D4 like 6 [Source:HGNC Symbol;Acc:HGNC:31986]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation"	Fork_head
ENSG00000273520	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE8	speedy/RINGO cell cycle regulator family member E8 [Source:HGNC Symbol;Acc:HGNC:33771]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000273540	0	0	0	0	0	0.011	0	0	0	0	0	2	AGBL1	AGBL carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:26504]	-	-	-	-	GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0035609//C-terminal protein deglutamylation;GO:0035610//protein side chain deglutamylation	--
ENSG00000273542	0.498	0.744	1.012	0.336	0	0.856	4	6	6	2	0	5	H4C12	H4 clustered histone 12 [Source:HGNC Symbol;Acc:HGNC:4784]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000273559	4.932	4.955	4.988	3.918	4.365	4.708	264	280	179	161	188	202	CWC25	CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005684//U2-type spliceosomal complex;GO:0016607//nuclear speck;GO:0071006//U2-type catalytic step 1 spliceosome	GO:0005515//protein binding	"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing"	--
ENSG00000273590	19.286	10.508	25.839	14.797	16.43	6.451	373.33	217	364.96	210.1	274.31	97.83	SMIM11B	small integral membrane protein 11B	-	-	-	-	-	-	-	--
ENSG00000273604	0.326	0.265	0.08	0.16	0.333	0.305	22	18	4	8	19	15	EPOP	elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493]	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0035098//ESC/E(Z) complex;GO:0070449//elongin complex	GO:0003682//chromatin binding	GO:0006357//regulation of transcription by RNA polymerase II;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination;GO:0048663//neuron fate commitment;GO:0048863//stem cell differentiation	--
ENSG00000273611	13.914	13.233	13.163	14.491	10.156	11.584	261	250	180	201	161	158	ZNHIT3	zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070761//pre-snoRNP complex	GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046966//thyroid hormone receptor binding	"GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000492//box C/D snoRNP assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0048254//snoRNA localization"	--
ENSG00000273696	0	0	0	0	0	0	0	0	0	0	0	0	CT45A7	cancer/testis antigen family 45 member A7 [Source:HGNC Symbol;Acc:HGNC:51260]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000273703	0	0	0	0	0	0	0	0	0	0	0	0	H2BC14	H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000273706	0.099	0.07	0.215	0.255	0.017	0.039	7	5	3	8	1	2	LHX1	LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593]	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005667//transcription regulator complex;GO:0032991//protein-containing complex	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990837//sequence-specific double-stranded DNA binding"	"GO:0001655//urogenital system development;GO:0001656//metanephros development;GO:0001657//ureteric bud development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001702//gastrulation with mouth forming second;GO:0001705//ectoderm formation;GO:0001706//endoderm formation;GO:0001822//kidney development;GO:0001823//mesonephros development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006366//transcription by RNA polymerase II;GO:0007267//cell-cell signaling;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0007492//endoderm development;GO:0008045//motor neuron axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0009791//post-embryonic development;GO:0009880//embryonic pattern specification;GO:0009887//animal organ morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0009952//anterior/posterior pattern specification;GO:0009953//dorsal/ventral pattern formation;GO:0010468//regulation of gene expression;GO:0010842//retina layer formation;GO:0021510//spinal cord development;GO:0021517//ventral spinal cord development;GO:0021527//spinal cord association neuron differentiation;GO:0021537//telencephalon development;GO:0021549//cerebellum development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021871//forebrain regionalization;GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0030154//cell differentiation;GO:0030182//neuron differentiation;GO:0032525//somite rostral/caudal axis specification;GO:0035502//metanephric part of ureteric bud development;GO:0035846//oviduct epithelium development;GO:0035847//uterine epithelium development;GO:0035849//nephric duct elongation;GO:0035852//horizontal cell localization;GO:0040019//positive regulation of embryonic development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048382//mesendoderm development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0048793//pronephros development;GO:0060041//retina development in camera-type eye;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0060065//uterus development;GO:0060066//oviduct development;GO:0060067//cervix development;GO:0060068//vagina development;GO:0060322//head development;GO:0060429//epithelium development;GO:0061205//paramesonephric duct development;GO:0072049//comma-shaped body morphogenesis;GO:0072050//S-shaped body morphogenesis;GO:0072077//renal vesicle morphogenesis;GO:0072164//mesonephric tubule development;GO:0072177//mesonephric duct development;GO:0072178//nephric duct morphogenesis;GO:0072197//ureter morphogenesis;GO:0072224//metanephric glomerulus development;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0072283//metanephric renal vesicle morphogenesis;GO:0072284//metanephric S-shaped body morphogenesis;GO:0090009//primitive streak formation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0097379//dorsal spinal cord interneuron posterior axon guidance;GO:0097477//lateral motor column neuron migration;GO:2000543//positive regulation of gastrulation;GO:2000744//positive regulation of anterior head development;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation"	Homeobox
ENSG00000273734	0	0	0	0	0	0	0	0	0	0	0	0	OAZ1	"novel protein, readthrough between OAZ1 and SPPL2B"	-	-	-	-	-	-	-	--
ENSG00000273749	21.585	21.413	24.967	22.302	23.668	22.065	2053.55	1981.82	1620.4	1495.37	1765.39	1488.64	CYFIP1	cytoplasmic FMR1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13759]	Human Diseases;Human Diseases;Cellular Processes	Infectious disease: bacterial;Infectious disease: bacterial;Cell motility	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko04810//Regulation of actin cytoskeleton	K05749;K05749;K05749	GO:0001726//ruffle;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005845//mRNA cap binding complex;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0031209//SCAR complex;GO:0032433//filopodium tip;GO:0034774//secretory granule lumen;GO:0035580//specific granule lumen;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043195//terminal bouton;GO:0043197//dendritic spine;GO:0044294//dendritic growth cone;GO:0044295//axonal growth cone;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0060076//excitatory synapse;GO:0070062//extracellular exosome;GO:0090724//central region of growth cone;GO:0090725//peripheral region of growth cone;GO:0098794//postsynapse;GO:1904724//tertiary granule lumen	GO:0000340//RNA 7-methylguanosine cap binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0031267//small GTPase binding;GO:0045182//translation regulator activity;GO:0051015//actin filament binding	"GO:0000902//cell morphogenesis;GO:0006417//regulation of translation;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0010592//positive regulation of lamellipodium assembly;GO:0016601//Rac protein signal transduction;GO:0030031//cell projection assembly;GO:0030032//lamellipodium assembly;GO:0030154//cell differentiation;GO:0030833//regulation of actin filament polymerization;GO:0031175//neuron projection development;GO:0031529//ruffle organization;GO:0031641//regulation of myelination;GO:0032869//cellular response to insulin stimulus;GO:0045773//positive regulation of axon extension;GO:0048675//axon extension;GO:0050772//positive regulation of axonogenesis;GO:0050890//cognition;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0051602//response to electrical stimulus;GO:0097484//dendrite extension;GO:0099563//modification of synaptic structure;GO:0099578//regulation of translation at postsynapse, modulating synaptic transmission;GO:1900006//positive regulation of dendrite development;GO:1900029//positive regulation of ruffle assembly;GO:1903422//negative regulation of synaptic vesicle recycling;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation"	--
ENSG00000273756	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L6	novel golgin subfamily A member 6-like protein	-	-	-	-	-	-	-	--
ENSG00000273777	0	0	0	0	0	0	0	0	0	0	0	0	CEACAM20	CEA cell adhesion molecule 20 [Source:HGNC Symbol;Acc:HGNC:24879]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0042995//cell projection	-	GO:0001819//positive regulation of cytokine production;GO:0002376//immune system process;GO:0009617//response to bacterium	--
ENSG00000273802	0.197	0	0	0	0	0.136	2	0	0	0	0	1	H2BC8	H2B clustered histone 8 [Source:HGNC Symbol;Acc:HGNC:4746]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000273820	1.96	2.543	2.399	1.841	2.245	1.853	125	163	113	87	121	86	USP27X	ubiquitin specific peptidase 27 X-linked [Source:HGNC Symbol;Acc:HGNC:13486]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004197//cysteine-type endopeptidase activity;GO:0004843//thiol-dependent deubiquitinase;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0016787//hydrolase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:1990380//Lys48-specific deubiquitinase activity	GO:0006508//proteolysis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0050821//protein stabilization;GO:0051607//defense response to virus;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination	--
ENSG00000273841	29.631	28.53	31.254	26.778	23.191	28.277	732.75	714.27	567.19	490.7	483	526.39	TAF9	TATA-box binding protein associated factor 9 [Source:HGNC Symbol;Acc:HGNC:11542]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K14535	GO:0000124//SAGA complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex;GO:0070761//pre-snoRNP complex;GO:0071339//MLL1 complex	GO:0000976//transcription cis-regulatory region binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0016251//RNA polymerase II general transcription initiation factor activity;GO:0046982//protein heterodimerization activity;GO:0051117//ATPase binding;GO:0070742//C2H2 zinc finger domain binding;GO:0140297//DNA-binding transcription factor binding	"GO:0000492//box C/D snoRNP assembly;GO:0006282//regulation of DNA repair;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006468//protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0016573//histone acetylation;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035521//monoubiquitinated histone deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0042789//mRNA transcription by RNA polymerase II;GO:0043066//negative regulation of apoptotic process;GO:0043484//regulation of RNA splicing;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050821//protein stabilization;GO:0051123//RNA polymerase II preinitiation complex assembly;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060760//positive regulation of response to cytokine stimulus;GO:0070555//response to interleukin-1;GO:1902065//response to L-glutamate;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator"	--
ENSG00000273899	7.494	7.43	9.703	10.988	8.328	7.116	160	159.92	143	165.92	153.63	107	NOL12	nucleolar protein 12 [Source:HGNC Symbol;Acc:HGNC:28585]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding;GO:0042802//identical protein binding	-	--
ENSG00000273962	0	0	0	0	0	0	0	0	0	0	0	0	IGKV2-40	immunoglobulin kappa variable 2-40 [Source:HGNC Symbol;Acc:HGNC:5789]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000273976	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L1	golgin A6 family like 1 [Source:HGNC Symbol;Acc:HGNC:37444]	-	-	-	-	-	-	-	--
ENSG00000273983	0	0	0	0.394	0	0	0	0	0	3	0	0	H3C8	H3 clustered histone 8 [Source:HGNC Symbol;Acc:HGNC:4772]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000274049	0.842	3.896	1.121	2.332	0	2.054	29.96	135.48	33.54	64.01	0	51.7	INO80B-WBP1	INO80B-WBP1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49199]	-	-	-	-	GO:0031011//Ino80 complex	-	GO:0006338//chromatin remodeling	--
ENSG00000274070	3.399	3.394	3.276	2.971	2.73	3.317	571	573.19	406.45	369.69	387.5	405.51	CASTOR2	cytosolic arginine sensor for mTORC1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:37073]	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K23081	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0061700//GATOR2 complex	GO:0005515//protein binding;GO:0042802//identical protein binding	GO:1902531//regulation of intracellular signal transduction;GO:1903577//cellular response to L-arginine;GO:1904262//negative regulation of TORC1 signaling	--
ENSG00000274102	0	0	0	0	0	0	0	0	0	0	0	0	OR4M2	olfactory receptor family 4 subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:15373]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000274180	8.907	9.124	8.578	9.57	9.142	8.076	911	938	648	725	790	601	NATD1	N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000274183	0	0	0	0	0	0	0	0	0	0	0	0	H2AB1	H2A.B variant histone 1 [Source:HGNC Symbol;Acc:HGNC:22516]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0035327//transcriptionally active chromatin	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly;GO:0006397//mRNA processing	--
ENSG00000274209	0	0	0	0	0	0	0	0	0	0	0	0	ANTXRL	ANTXR like [Source:HGNC Symbol;Acc:HGNC:27277]	-	-	-	-	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding	GO:1901998//toxin transport	--
ENSG00000274211	5.277	6.143	7.846	5.91	5.968	7.095	710	737	494	528	510	552	SOCS7	suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846]	Environmental Information Processing;Organismal Systems	Signal transduction;Endocrine system	ko04630//JAK-STAT signaling pathway;ko04917//Prolactin signaling pathway	K04699;K04699	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016020//membrane	GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity	GO:0008150//biological_process;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0040008//regulation of growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000274226	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D3H	TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274252	0	0	0	0	0	0	0	0	0	0	0	0	GGTLC3	gamma-glutamyltransferase light chain family member 3 [Source:HGNC Symbol;Acc:HGNC:33426]	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Metabolism of other amino acids;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism;ko00480//Glutathione metabolism;ko00430//Taurine and hypotaurine metabolism	K18592;K18592;K18592;K18592	GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0036374//glutathione hydrolase activity	GO:0006508//proteolysis;GO:0006751//glutathione catabolic process;GO:0008150//biological_process;GO:1901750//leukotriene D4 biosynthetic process	--
ENSG00000274274	0	0	0	0	0	0	0	0	0	0	0	0	GAGE13	G antigen 13 [Source:HGNC Symbol;Acc:HGNC:29081]	-	-	-	-	-	-	-	--
ENSG00000274276	7.434	8.753	8.994	12.586	10.655	13.523	370.88	450.06	334.47	473.89	457.09	506.2	CBSL	cystathionine-beta-synthase like	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko01230//Biosynthesis of amino acids;ko00270//Cysteine and methionine metabolism;ko00260//Glycine, serine and threonine metabolism"	K01697;K01697;K01697;K01697	GO:0005737//cytoplasm	GO:0004122//cystathionine beta-synthase activity	GO:0006535//cysteine biosynthetic process from serine;GO:0019343//cysteine biosynthetic process via cystathionine	--
ENSG00000274286	9.157	9.071	3.108	3.029	4.323	2.85	702	699	176	172	280	159	ADRA2B	adrenoceptor alpha 2B [Source:HGNC Symbol;Acc:HGNC:282]	Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04022//cGMP-PKG signaling pathway	K04139;K04139	GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	GO:0004930//G protein-coupled receptor activity;GO:0004935//adrenergic receptor activity;GO:0004938//alpha2-adrenergic receptor activity;GO:0005515//protein binding;GO:0051379//epinephrine binding	GO:0003056//regulation of vascular associated smooth muscle contraction;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0010700//negative regulation of norepinephrine secretion;GO:0019229//regulation of vasoconstriction;GO:0030168//platelet activation;GO:0032148//activation of protein kinase B activity;GO:0032811//negative regulation of epinephrine secretion;GO:0035624//receptor transactivation;GO:0043410//positive regulation of MAPK cascade;GO:0045666//positive regulation of neuron differentiation;GO:0045777//positive regulation of blood pressure;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0071875//adrenergic receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway	--
ENSG00000274290	0.075	0.074	0.076	0.05	0.022	0	4	4	3	2	1	0	H2BC6	H2B clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4753]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000274322	0	0	0	0	0	0	0	0	0	0	0	0	FKBP1A	novel protein	-	-	-	-	-	-	-	--
ENSG00000274349	3.613	3.133	3.035	2.244	2.487	2.756	270	246	189	139	175	171	ZNF658	zinc finger protein 658 [Source:HGNC Symbol;Acc:HGNC:25226]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0042254//ribosome biogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0071294//cellular response to zinc ion"	zf-C2H2
ENSG00000274386	0.057	0	0.019	0.05	0.017	0	4	0	1	1	1	0	TMEM269	transmembrane protein 269 [Source:HGNC Symbol;Acc:HGNC:52381]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000274391	0	0	0	0	0	0	0	0	0	0	0	0	TPTE	transmembrane phosphatase with tensin homology [Source:HGNC Symbol;Acc:HGNC:12023]	-	-	-	-	GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection	"GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity"	GO:0006470//protein dephosphorylation;GO:0007165//signal transduction;GO:0008285//negative regulation of cell population proliferation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046856//phosphatidylinositol dephosphorylation;GO:0048870//cell motility;GO:0051896//regulation of protein kinase B signaling	--
ENSG00000274419	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D3D	TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274443	0	0	0	0	0	0	0	0	0	0	0	0	C8orf89	chromosome 8 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:51258]	-	-	-	-	-	-	-	--
ENSG00000274512	2.431	1.529	3.233	3.077	2.429	3.427	143.95	82.31	142.08	123	124.17	132.07	TBC1D3L	TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274523	17.508	19.866	20.146	22.118	21.055	22.029	832	957.81	709.55	774.31	848.5	757.49	RCC1L	RCC1 like [Source:HGNC Symbol;Acc:HGNC:14948]	-	-	-	-	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0031966//mitochondrial membrane	GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0019843//rRNA binding	GO:0050790//regulation of catalytic activity;GO:0070131//positive regulation of mitochondrial translation;GO:1990613//mitochondrial membrane fusion	--
ENSG00000274529	0	0	0.047	0	0	0	0	0	1	0	0	0	SEBOX	SEBOX homeobox [Source:HGNC Symbol;Acc:HGNC:32942]	-	-	-	-	GO:0005575//cellular_component;GO:0005634//nucleus	GO:0003677//DNA binding	GO:0009792//embryo development ending in birth or egg hatching;GO:0030154//cell differentiation;GO:0048477//oogenesis	Homeobox
ENSG00000274559	0	0	0	0	0	0	0	0	0	0	0	0	H2BS1	novel histone H2B family protein	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000274570	0	0	0	0.065	0.055	0	0	0	0	3.08	2.94	0	SPDYE10	speedy/RINGO cell cycle regulator family member E10 [Source:HGNC Symbol;Acc:HGNC:51506]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000274576	0	0	0	0	0	0	0	0	0	0	0	0	IGHV2-70	immunoglobulin heavy variable 2-70 [Source:HGNC Symbol;Acc:HGNC:5577]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006955//immune response;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000274588	0	0	0	0	0	0	0	0	0	0	0	0	DGKK	diacylglycerol kinase kappa [Source:HGNC Symbol;Acc:HGNC:32395]	Metabolism;Environmental Information Processing;Human Diseases;Metabolism;Environmental Information Processing;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Cancer: overview;Lipid metabolism;Signal transduction;Lipid metabolism;Development and regeneration	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko04070//Phosphatidylinositol signaling system;ko00561//Glycerolipid metabolism;ko04361//Axon regeneration	K00901;K00901;K00901;K00901;K00901;K00901;K00901	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0006629//lipid metabolic process;GO:0006979//response to oxidative stress;GO:0007165//signal transduction;GO:0007205//protein kinase C-activating G protein-coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046339//diacylglycerol metabolic process;GO:0046486//glycerolipid metabolic process;GO:0046834//lipid phosphorylation	--
ENSG00000274600	0.041	0	0	0.075	0.081	0	5.2	0	0	7	8.67	0	RIMBP3B	RIMS binding protein 3B [Source:HGNC Symbol;Acc:HGNC:33891]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0030156//benzodiazepine receptor binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009566//fertilization;GO:0030154//cell differentiation	--
ENSG00000274611	0	0	0	0	0	0	0	0	0	0	0	0	TBC1D3	TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031901//early endosome membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274618	0	0	0	0	0	0	0	0	0	0	0	0	H4C6	H4 clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4783]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000274641	0	0	0	0	0	0	0	0	0	0	0	0	H2BC17	H2B clustered histone 17 [Source:HGNC Symbol;Acc:HGNC:4758]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000274736	0	0	0	0	0	0	0	0	0	0	0	0	CCL23	C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05511;K05511;K05511	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0031726//CCR1 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008285//negative regulation of cell population proliferation;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:2001264//negative regulation of C-C chemokine binding	--
ENSG00000274749	0.134	0	0.181	0.542	0.158	0.276	2	0	2	6	2	3	KRTAP7-1	keratin associated protein 7-1 [Source:HGNC Symbol;Acc:HGNC:18934]	-	-	-	-	GO:0005882//intermediate filament	GO:0005515//protein binding	-	--
ENSG00000274750	1.817	1.038	1.048	1.457	1.001	1.509	56	58	43	49	47	61	H3C6	H3 clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4769]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000274764	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF27	PRAME family member 27 [Source:HGNC Symbol;Acc:HGNC:51234]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000274808	0.169	0.169	0	0.229	0.602	1.165	2	2	0	2	6	10	TBC1D3B	TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274810	1.326	0.416	0.5	1.432	0.509	0.436	68.44	63.99	59.62	46.4	69.45	51.2	NPHP3-ACAD11	NPHP3-ACAD11 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48351]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005871//kinesin complex;GO:0005874//microtubule	GO:0005515//protein binding	-	--
ENSG00000274933	0.203	0.253	0	0.149	0.154	0.105	8.34	10.47	0	4.53	5.34	3.14	TBC1D3I	TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000274944	0	0	0	0	0	0	0	0	0	0	0	0	GJA9	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0003713//transcription coactivator activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0007154//cell communication;GO:0045893//positive regulation of transcription, DNA-templated"	--
ENSG00000274997	0	0	0.143	0	0	0	0	0	1	0	0	0	H2AC12	H2A clustered histone 12 [Source:HGNC Symbol;Acc:HGNC:13671]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000275004	1.462	1.653	1.192	1.223	1.473	1.57	161	183	96	98	131	118	ZNF280B	zinc finger protein 280B [Source:HGNC Symbol;Acc:HGNC:23022]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Others
ENSG00000275023	7.426	7.995	8.132	8.021	9.465	10.109	1205	1225	952	966	1253	1196	MLLT6	"MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138]"	-	-	-	-	GO:0005634//nucleus	GO:0005515//protein binding;GO:0031491//nucleosome binding;GO:0042393//histone binding;GO:0046872//metal ion binding	"GO:0003014//renal system process;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0010765//positive regulation of sodium ion transport;GO:0035811//negative regulation of urine volume;GO:0035812//renal sodium excretion;GO:0036359//renal potassium excretion;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0070295//renal water absorption;GO:2001161//negative regulation of histone H3-K79 methylation"	--
ENSG00000275034	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3E	TP53 target 3 family member E [Source:HGNC Symbol;Acc:HGNC:51816]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000275052	29.02	22.583	22.052	17.421	19.066	20.45	2867	2240	1623	1276	1618	1477	PPP4R3B	protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267]	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K17491	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0030289//protein phosphatase 4 complex	GO:0072542//protein phosphatase activator activity	GO:0006470//protein dephosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0016576//histone dephosphorylation;GO:0033128//negative regulation of histone phosphorylation;GO:0045722//positive regulation of gluconeogenesis;GO:0050790//regulation of catalytic activity;GO:2000779//regulation of double-strand break repair	--
ENSG00000275066	14.3	15.442	15.516	11.056	12.235	12.088	1488	1575	1183	931	1224	1013	SYNRG	synergin gamma [Source:HGNC Symbol;Acc:HGNC:557]	-	-	-	-	GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030121//AP-1 adaptor complex;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030136//clathrin-coated vesicle;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm	GO:0005515//protein binding	GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0015031//protein transport	--
ENSG00000275074	3.269	2.652	2.751	3.406	4.17	2.762	109	91	69	83	115	67	NUDT18	nudix hydrolase 18 [Source:HGNC Symbol;Acc:HGNC:26194]	-	-	-	-	GO:0005829//cytosol	GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0044715//8-oxo-dGDP phosphatase activity;GO:0044716//8-oxo-GDP phosphatase activity;GO:0044717//8-hydroxy-dADP phosphatase activity;GO:0046872//metal ion binding	GO:0009117//nucleotide metabolic process;GO:0046057//dADP catabolic process;GO:0046067//dGDP catabolic process;GO:0046712//GDP catabolic process;GO:0055086//nucleobase-containing small molecule metabolic process	--
ENSG00000275111	3.118	4.033	3.541	3.044	3.53	3.741	190	215	146	122	168	147	ZNF2	zinc finger protein 2 [Source:HGNC Symbol;Acc:HGNC:12991]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000275113	0	0	0	0	0	0	0	0	0	0	0	0	GAGE2E	G antigen 2E [Source:HGNC Symbol;Acc:HGNC:31960]	-	-	-	-	-	-	-	--
ENSG00000275126	0	0	0	0	0	0	0	0	0	0	0	0	H4C13	H4 clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4791]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000275152	0	0	0	0	0	0	0	0	0	0	0	0	CCL16	C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21093;K21093;K21093	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0042056//chemoattractant activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000275163	0.035	0	0	0	0	0	1	0	0	0	0	0	KCNMB2	"potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)"	Environmental Information Processing;Organismal Systems;Organismal Systems	Signal transduction;Circulatory system;Endocrine system	ko04022//cGMP-PKG signaling pathway;ko04270//Vascular smooth muscle contraction;ko04911//Insulin secretion	K04938;K04938;K04938	GO:0016020//membrane	GO:0015269//calcium-activated potassium channel activity	GO:0006813//potassium ion transport	--
ENSG00000275183	1.06	1.031	0.8	0.893	0.867	0.939	45	44	25.08	28.09	31.09	29	LENG9	leukocyte receptor cluster member 9 [Source:HGNC Symbol;Acc:HGNC:16306]	-	-	-	-	-	GO:0046872//metal ion binding	-	--
ENSG00000275221	0.389	0	0.132	0.131	0.115	0.134	4	0	1	1	1	1	H2AC15	H2A clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:4726]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000275302	0	0	0	0	0	0	0	0	0	0	0	0	CCL4	C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630]	Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Immune system;Signal transduction;Immune system;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04623//Cytosolic DNA-sensing pathway	K12964;K12964;K12964;K12964;K12964;K12964;K12964	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0031726//CCR1 chemokine receptor binding;GO:0031730//CCR5 chemokine receptor binding;GO:0042802//identical protein binding;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0009615//response to virus;GO:0009636//response to toxic substance;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0043922//negative regulation by host of viral transcription;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050850//positive regulation of calcium-mediated signaling;GO:0051928//positive regulation of calcium ion transport;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:2000503//positive regulation of natural killer cell chemotaxis	--
ENSG00000275342	1.025	0.829	0.539	0.739	0.887	1.08	103	83	40	55	73	79	PRAG1	"PEAK1 related, kinase-activating pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:25438]"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030054//cell junction	GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding	GO:0006468//protein phosphorylation;GO:0008360//regulation of cell shape;GO:0008593//regulation of Notch signaling pathway;GO:0010977//negative regulation of neuron projection development;GO:0016477//cell migration;GO:0035025//positive regulation of Rho protein signal transduction;GO:2000145//regulation of cell motility	--
ENSG00000275379	0	0	0.13	0	0	0	0	0	1	0	0	0	H3C11	H3 clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4771]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000275385	0	0	0.098	0.098	0.043	0	0	0	2	2	1	0	CCL18	C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21094;K21094;K21094	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007154//cell communication;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000275395	0.181	0.154	0.225	0.137	0.183	0.124	48	41	44	27	41	24	FCGBP	Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000275410	0.035	0.067	0	0	0	0	2	3	0	0	0	0	HNF1B	HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630]	Human Diseases	Endocrine and metabolic disease	ko04950//Maturity onset diabetes of the young	K08034	GO:0000785//chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0043231//intracellular membrane-bounded organelle	"GO:0000976//transcription cis-regulatory region binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0001221//transcription coregulator binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0044877//protein-containing complex binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001714//endodermal cell fate specification;GO:0001822//kidney development;GO:0001826//inner cell mass cell differentiation;GO:0001889//liver development;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007219//Notch signaling pathway;GO:0007492//endoderm development;GO:0009410//response to xenobiotic stimulus;GO:0009743//response to carbohydrate;GO:0009749//response to glucose;GO:0009952//anterior/posterior pattern specification;GO:0010628//positive regulation of gene expression;GO:0014070//response to organic cyclic compound;GO:0030073//insulin secretion;GO:0030111//regulation of Wnt signaling pathway;GO:0030902//hindbrain development;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0032922//circadian regulation of gene expression;GO:0035565//regulation of pronephros size;GO:0039020//pronephric nephron tubule development;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048557//embryonic digestive tract morphogenesis;GO:0048598//embryonic morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048793//pronephros development;GO:0048806//genitalia development;GO:0050673//epithelial cell proliferation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060429//epithelium development;GO:0060677//ureteric bud elongation;GO:0060993//kidney morphogenesis;GO:0061017//hepatoblast differentiation;GO:0061296//negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis;GO:0065004//protein-DNA complex assembly;GO:0070365//hepatocyte differentiation;GO:0072095//regulation of branch elongation involved in ureteric bud branching;GO:0072164//mesonephric tubule development;GO:0072176//nephric duct development;GO:0072177//mesonephric duct development;GO:0072179//nephric duct formation;GO:0072181//mesonephric duct formation;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development"	Homeobox
ENSG00000275464	6.007	6.229	4.791	5.78	5.245	6.509	377.82	414	234	283.11	293.02	307	PWP2	"novel protein, similar to PWP2 periodic tryptophan protein homolog (yeast) PWP2"	Genetic Information Processing	Translation	ko03008//Ribosome biogenesis in eukaryotes	K14558	GO:0005730//nucleolus;GO:0031981//nuclear lumen;GO:0032040//small-subunit processome;GO:0034388//Pwp2p-containing subcomplex of 90S preribosome	GO:0005515//protein binding	"GO:0000028//ribosomal small subunit assembly;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing"	--
ENSG00000275489	0	0	0	0	0	0	0	0	0	0	0	0	C17orf98	chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492]	-	-	-	-	-	-	-	--
ENSG00000275520	0	0	0	0	0	0	0	0	0	0	0	0	FAM236A	family with sequence similarity 235 member A [Source:HGNC Symbol;Acc:HGNC:44268]	-	-	-	-	-	-	-	--
ENSG00000275553	0	0	0	0	0	0	0	0	0	0	0	0	ELOA3CP	"elongin A3 family member C, pseudogene [Source:HGNC Symbol;Acc:HGNC:52410]"	-	-	-	-	GO:0005634//nucleus;GO:0070449//elongin complex	-	GO:0006368//transcription elongation from RNA polymerase II promoter	--
ENSG00000275572	0	0	0	0	0	0	0	0	0	0	0	0	GRIFIN	galectin-related inter-fiber protein [Source:HGNC Symbol;Acc:HGNC:4577]	-	-	-	-	GO:0005737//cytoplasm	GO:0030246//carbohydrate binding	-	--
ENSG00000275591	0.01	0.01	0	0.027	0.012	0	1	1	0	2	1	0	XKR5	XK related 5 [Source:HGNC Symbol;Acc:HGNC:20782]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface;GO:1902742//apoptotic process involved in development	--
ENSG00000275663	0	0	0	0	0	0	0	0	0	0	0	0	H4C7	H4 clustered histone 7 [Source:HGNC Symbol;Acc:HGNC:4792]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly;GO:0008150//biological_process	--
ENSG00000275674	0	0	0	0	0	0	0	0	0	0	0	0	NGRN	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0031966//mitochondrial membrane	-	-	--
ENSG00000275688	0	0	0	0	0	0	0	0	0	0	0	0	CCL15-CCL14	CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05511;K05511;K05511	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity	GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007165//signal transduction;GO:0060326//cell chemotaxis	--
ENSG00000275700	16.203	16.134	16.002	14.559	15.805	13.734	694	694	505	461	573	429	AATF	apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043522//leucine zipper domain binding;GO:0048156//tau protein binding	"GO:0006357//regulation of transcription by RNA polymerase II;GO:0006974//cellular response to DNA damage stimulus;GO:0007155//cell adhesion;GO:0007346//regulation of mitotic cell cycle;GO:0032929//negative regulation of superoxide anion generation;GO:0040016//embryonic cleavage;GO:0042254//ribosome biogenesis;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:2001234//negative regulation of apoptotic signaling pathway"	--
ENSG00000275713	0	0	0	0	0	0	0	0	0	0	0	0	H2BC9	H2B clustered histone 9 [Source:HGNC Symbol;Acc:HGNC:4755]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0097677//STAT family protein binding	GO:0006334//nucleosome assembly	--
ENSG00000275714	0	0	0	0	0	0	0	0	0	0	0	0	H3C1	H3 clustered histone 1 [Source:HGNC Symbol;Acc:HGNC:4766]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000275718	0	0	0	0	0	0	0	0	0	0	0	0	CCL15	C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05511;K05511;K05511	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005102//signaling receptor binding;GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000275722	0	0	0	0	0	0	0	0	0	0	0	0	LYZL6	lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614]	-	-	-	-	GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0005929//cilium;GO:0009986//cell surface;GO:0031514//motile cilium;GO:0036126//sperm flagellum;GO:0042995//cell projection;GO:0097225//sperm midpiece;GO:0097524//sperm plasma membrane	"GO:0003796//lysozyme activity;GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0007338//single fertilization;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0008152//metabolic process;GO:0009566//fertilization;GO:0019835//cytolysis;GO:0042742//defense response to bacterium	--
ENSG00000275740	1.245	1.026	0.62	0.51	0.532	0.952	85.51	70.83	31.46	25.95	30.87	47.55	RBM27	novel readthrough transcript	-	-	-	-	-	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0046872//metal ion binding	GO:0006397//mRNA processing	--
ENSG00000275774	0	0	0	0	0	0	0	0	0	0	0	0	HNRNPCL2	heterogeneous nuclear ribonucleoprotein C like 2 [Source:HGNC Symbol;Acc:HGNC:48813]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12884	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding	-	--
ENSG00000275778	0.963	1.133	0.917	0.716	0.761	1.07	16	23.43	12.75	8.76	13.41	17.38	PRH1	PRH1-PRR4 readthrough	Organismal Systems	Digestive system	ko04970//Salivary secretion	K13910	-	GO:0005515//protein binding	-	--
ENSG00000275793	0.062	0.015	0.064	0	0.04	0.076	7.8	1.94	6	0	4.33	7	RIMBP3	RIMS binding protein 3 [Source:HGNC Symbol;Acc:HGNC:29344]	-	-	-	-	GO:0002177//manchette;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton	GO:0005515//protein binding;GO:0030156//benzodiazepine receptor binding	GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009566//fertilization;GO:0030154//cell differentiation	--
ENSG00000275832	30.325	30.835	31.195	45.374	45.044	48.664	2713	2793	2241	2804	3175	2888	ARHGAP23	Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293]	-	-	-	-	GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000275835	7.307	5.151	4.824	4.604	4.342	5.695	403	374	239	209	229	223	TUBGCP5	tubulin gamma complex associated protein 5 [Source:HGNC Symbol;Acc:HGNC:18600]	-	-	-	-	GO:0000922//spindle pole;GO:0000923//equatorial microtubule organizing center;GO:0000930//gamma-tubulin complex;GO:0000931//gamma-tubulin large complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043015//gamma-tubulin binding;GO:0051011//microtubule minus-end binding	GO:0000226//microtubule cytoskeleton organization;GO:0000278//mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0031122//cytoplasmic microtubule organization;GO:0051225//spindle assembly;GO:0051321//meiotic cell cycle	--
ENSG00000275895	6.843	3.365	8.543	8.285	3.608	6.554	118.57	57.04	107.02	103.71	52.82	81.57	U2AF1	U2 small nuclear RNA auxiliary factor 1-like 5	Human Diseases;Genetic Information Processing	Infectious disease: bacterial;Transcription	ko05131//Shigellosis;ko03040//Spliceosome	K12836;K12836	GO:0089701//U2AF complex	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0046872//metal ion binding	"GO:0000398//mRNA splicing, via spliceosome"	--
ENSG00000275896	0	0	0	0	0	0	0	0	0	0	0	0	PRSS2	serine protease 2 [Source:HGNC Symbol;Acc:HGNC:9483]	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Digestive system;Digestive system	ko04080//Neuroactive ligand-receptor interaction;ko05164//Influenza A;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption	K01312;K01312;K01312;K01312	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0035578//azurophil granule lumen	GO:0004222//metalloendopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007586//digestion;GO:0019730//antimicrobial humoral response;GO:0022617//extracellular matrix disassembly;GO:0030307//positive regulation of cell growth;GO:0030574//collagen catabolic process;GO:0045785//positive regulation of cell adhesion	--
ENSG00000275954	0.322	0.229	0.504	0.344	0.498	0.563	14.13	10.09	16.36	11.2	18.48	17.99	TBC1D3F	TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257]	-	-	-	-	-	-	-	--
ENSG00000275969	0.073	0.155	0.073	0.022	0.18	0.218	6.41	13.75	4.76	1.44	13.41	14	SPATA31A3	SPATA31 subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:32003]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000275976	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE11	speedy/RINGO cell cycle regulator family member E11 [Source:HGNC Symbol;Acc:HGNC:51507]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding;GO:0030548//acetylcholine receptor regulator activity	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000275993	18.729	21.31	17.725	10.571	14.155	13.194	1844.1	2109	1289	771	1177.48	945.23	SIK1B	"novel protein, similar to salt-inducible kinase 1 SIK1"	Organismal Systems	Endocrine system	ko04922//Glucagon signaling pathway	K19008	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0106310//protein serine kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation	--
ENSG00000276023	5.552	5.613	5.491	4.725	4.397	5.619	172	174	124	107	114	125	DUSP14	dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007]	-	-	-	-	-	GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation	--
ENSG00000276040	0	0	0	0	0.024	0	0	0	0	0	1.81	0	SPATA31A7	SPATA31 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:32007]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000276043	0.662	1.009	1.007	0.855	0.571	0.628	53	63	53	42	39	33	UHRF1	ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556]	-	-	-	-	GO:0000785//chromatin;GO:0000791//euchromatin;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0016363//nuclear matrix	GO:0000987//cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0016740//transferase activity;GO:0031493//nucleosomal histone binding;GO:0035064//methylated histone binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0044729//hemi-methylated DNA-binding;GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006281//DNA repair;GO:0006325//chromatin organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0010216//maintenance of DNA methylation;GO:0010390//histone monoubiquitination;GO:0016567//protein ubiquitination;GO:0016574//histone ubiquitination;GO:0032270//positive regulation of cellular protein metabolic process;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0050678//regulation of epithelial cell proliferation;GO:0051865//protein autoubiquitination;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	--
ENSG00000276045	14.502	14.492	15.054	14.401	15.716	14.838	450	452	345	331	412	335	ORAI1	ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Endocrine and metabolic disease;Immune system;Immune disease;Endocrine system;Endocrine system;Endocrine system	ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04934//Cushing syndrome;ko04611//Platelet activation;ko05340//Primary immunodeficiency;ko04925//Aldosterone synthesis and secretion;ko04924//Renin secretion;ko04927//Cortisol synthesis and secretion	K16056;K16056;K16056;K16056;K16056;K16056;K16056;K16056	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0032991//protein-containing complex;GO:0034704//calcium channel complex;GO:0044853//plasma membrane raft;GO:0045121//membrane raft	GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015279//store-operated calcium channel activity;GO:0042802//identical protein binding	GO:0002115//store-operated calcium entry;GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006811//ion transport;GO:0006816//calcium ion transport;GO:0045762//positive regulation of adenylate cyclase activity;GO:0051924//regulation of calcium ion transport;GO:0051928//positive regulation of calcium ion transport;GO:0061180//mammary gland epithelium development;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport	--
ENSG00000276070	0	0	0	0	0	0	0	0	0	0	0	0	CCL4L2	C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066]	Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Infectious disease: viral;Immune system;Signal transduction;Immune system;Signaling molecules and interaction;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko04062//Chemokine signaling pathway;ko04064//NF-kappa B signaling pathway;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04623//Cytosolic DNA-sensing pathway	K12964;K12964;K12964;K12964;K12964;K12964;K12964	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048245//eosinophil chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000276076	0.915	1.903	1.713	1.637	1.77	1.098	31.03	45.78	26.22	24.6	29.44	21.21	CRYAA2	"novel protein, similar to crystallin, alpha A CRYAA"	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09541	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0005212//structural constituent of eye lens;GO:0046872//metal ion binding	-	--
ENSG00000276085	0	0	0	0	0.146	0	0	0	0	0	2	0	CCL3L1	C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune system;Immune disease;Infectious disease: parasitic;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko05323//Rheumatoid arthritis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05408;K05408;K05408;K05408;K05408;K05408;K05408;K05408	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008285//negative regulation of cell population proliferation;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000276087	0.042	0	0.031	0	0	0	2	0	1.1	0	0	0	FAM228B	novel transcript	-	-	-	-	-	-	-	--
ENSG00000276119	0	0	0	0	0	0	0	0	0	0	0	0	OR13C2	olfactory receptor family 13 subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:14701]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000276180	0.121	0	0	0	0	0	1	0	0	0	0	0	H4C9	H4 clustered histone 9 [Source:HGNC Symbol;Acc:HGNC:4793]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000276203	0.115	0.028	0	0	0	0.057	4.12	1	0	0	0	2	ANKRD20A3P	"ankyrin repeat domain 20 family member A3, pseudogene [Source:HGNC Symbol;Acc:HGNC:31981]"	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000276231	0	0	0	0	0	0	0	0	0	0	0	0	PIK3R6	phosphoinositide-3-kinase regulatory subunit 6 [Source:HGNC Symbol;Acc:HGNC:27101]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Immune system;Signal transduction;Endocrine system;Circulatory system;Signal transduction;Immune system;Nervous system;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko04072//Phospholipase D signaling pathway;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04371//Apelin signaling pathway;ko04611//Platelet activation;ko04725//Cholinergic synapse;ko05145//Toxoplasmosis	K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290;K21290	"GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0016020//membrane"	"GO:0005515//protein binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity"	GO:0001525//angiogenesis;GO:0006955//immune response;GO:0007186//G protein-coupled receptor signaling pathway;GO:0042269//regulation of natural killer cell mediated cytotoxicity;GO:0043406//positive regulation of MAP kinase activity;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045582//positive regulation of T cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0046854//phosphatidylinositol phosphate biosynthetic process	--
ENSG00000276234	3.477	4.003	4.956	3.67	4.045	3.7	170	181	154	130	149	128	TADA2A	transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531]	-	-	-	-	GO:0005634//nucleus;GO:0072686//mitotic spindle;GO:0140672//ATAC complex	GO:0003713//transcription coactivator activity;GO:0005515//protein binding	"GO:0000278//mitotic cell cycle;GO:0001932//regulation of protein phosphorylation;GO:0006357//regulation of transcription by RNA polymerase II;GO:0031063//regulation of histone deacetylation;GO:0031647//regulation of protein stability;GO:0035065//regulation of histone acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045995//regulation of embryonic development;GO:0051302//regulation of cell division;GO:0051726//regulation of cell cycle;GO:0090043//regulation of tubulin deacetylation"	MYB
ENSG00000276240	0	0	0	0	0	0	0	0	0	0	0	0	OR4E1	olfactory receptor family 4 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:8296]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000276289	0.417	1.03	0.183	0.216	0.062	0.12	27.21	52.15	8.85	7.22	3.44	5.72	KCNE1B	"potassium channel, voltage gated subfamily E regulatory beta subunit 1B"	Organismal Systems	Circulatory system	ko04261//Adrenergic signaling in cardiomyocytes	K04894	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0015459//potassium channel regulator activity;GO:0044325//transmembrane transporter binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086011//membrane repolarization during action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1902260//negative regulation of delayed rectifier potassium channel activity	--
ENSG00000276293	26.09	26.845	26.481	24.98	25.294	24.606	2892	2970	2142	2066	2386	1999	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998]	Metabolism;Cellular Processes;Environmental Information Processing;Metabolism	Global and overview maps;Cell motility;Signal transduction;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04810//Regulation of actin cytoskeleton;ko04070//Phosphatidylinositol signaling system;ko00562//Inositol phosphate metabolism	K00920;K00920;K00920;K00920	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0016301//kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity	"GO:0006629//lipid metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0010506//regulation of autophagy;GO:0016310//phosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphate biosynthetic process;GO:0061909//autophagosome-lysosome fusion;GO:0090217//negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:1902635//1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process;GO:2000786//positive regulation of autophagosome assembly"	--
ENSG00000276302	0.093	0	0.234	0	0	0	1.07	0	2	0	0	0	ZSCAN26	novel protein	-	-	-	-	-	-	-	--
ENSG00000276368	0	0	0	0	0	0	0	0	0	0	0	0	H2AC14	H2A clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4727]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000276380	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000276409	0	0	0	0	0	0	0	0	0	0	0	0	CCL14	C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612]	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K21092;K21092;K21092	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding	GO:0002548//monocyte chemotaxis;GO:0006874//cellular calcium ion homeostasis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0008284//positive regulation of cell population proliferation;GO:0030593//neutrophil chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0048247//lymphocyte chemotaxis;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor	--
ENSG00000276410	0	0	0	0	0	0	0	0	0	0	0	0	H2BC3	H2B clustered histone 3 [Source:HGNC Symbol;Acc:HGNC:4751]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	"GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol"	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000276418	0.038	0.173	0	0.103	0.092	0	1.21	5.5	0	2.41	2.47	0	TPD52	"novel protein, TPD52-MRPS28 readthrough"	-	-	-	-	GO:0110165//cellular anatomical entity	-	-	--
ENSG00000276430	0	0	0	0	0	0	0	0	0	0	0	0	FAM25C	family with sequence similarity 25 member C [Source:HGNC Symbol;Acc:HGNC:23586]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000276490	0	0	0	0	0	0	0	0	0	0	0	0	CYP2C18	novel transcript	Metabolism;Organismal Systems;Human Diseases;Metabolism	Global and overview maps;Nervous system;Cancer: overview;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04726//Serotonergic synapse;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism	K17720;K17720;K17720;K17720	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding"	GO:0006082//organic acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019373//epoxygenase P450 pathway	--
ENSG00000276547	0.976	0.883	0.575	0.968	1.234	0.811	96.26	87.52	41.86	70.69	102.8	58.2	PCDHGB5	"protocadherin gamma subfamily B, 5 [Source:HGNC Symbol;Acc:HGNC:8712]"	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0008150//biological_process	--
ENSG00000276566	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-13	immunoglobulin kappa variable 1D-13 [Source:HGNC Symbol;Acc:HGNC:5747]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000276581	0.026	0.037	0.107	0.178	0.051	0	2.29	3.24	6.95	11.56	3.77	0	SPATA31A5	SPATA31 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:32005]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007283//spermatogenesis;GO:0030154//cell differentiation	--
ENSG00000276600	0.479	0.43	0.227	0.942	0.466	0.608	25	25	10	34	21	24	RAB7B	"RAB7B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30513]"	Human Diseases;Cellular Processes;Human Diseases;Cellular Processes;Cellular Processes	Infectious disease: bacterial;Transport and catabolism;Infectious disease: parasitic;Transport and catabolism;Transport and catabolism	ko05132//Salmonella infection;ko04145//Phagosome;ko05146//Amoebiasis;ko04140//Autophagy - animal;ko04137//Mitophagy - animal	K07898;K07898;K07898;K07898;K07898	GO:0005764//lysosome;GO:0005768//endosome;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0031410//cytoplasmic vesicle;GO:0031902//late endosome membrane;GO:0045335//phagocytic vesicle	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005525//GTP binding	GO:0008333//endosome to lysosome transport;GO:0015031//protein transport;GO:0032755//positive regulation of interleukin-6 production;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0034499//late endosome to Golgi transport;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071346//cellular response to interferon-gamma;GO:0090385//phagosome-lysosome fusion	--
ENSG00000276612	0	0	0	0	0	0	0	0	0	0	0	0	GATD3A	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005739//mitochondrion	-	-	--
ENSG00000276644	3.018	2.501	1.824	2.837	2.561	2.576	305	258	127	219	231	182	DACH1	dachshund family transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2663]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001967//suckling behavior;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007585//respiratory gaseous exchange by respiratory system;GO:0008283//cell population proliferation;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0030336//negative regulation of cell migration;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046545//development of primary female sexual characteristics;GO:0048147//negative regulation of fibroblast proliferation;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:2000279//negative regulation of DNA biosynthetic process"	DACH
ENSG00000276699	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ36	T cell receptor alpha joining 36 [Source:HGNC Symbol;Acc:HGNC:12066]	-	-	-	-	-	-	-	--
ENSG00000276747	0	0.02	0	0	0	0	0	1	0	0	0	0	PADI6	peptidyl arginine deiminase 6 [Source:HGNC Symbol;Acc:HGNC:20449]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0045111//intermediate filament cytoskeleton;GO:0060473//cortical granule	GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0016787//hydrolase activity	GO:0007010//cytoskeleton organization;GO:0007028//cytoplasm organization;GO:0018101//protein citrullination;GO:0034613//cellular protein localization;GO:0036414//histone citrullination;GO:0040016//embryonic cleavage;GO:0043143//regulation of translation by machinery localization	--
ENSG00000276775	0	0	0	0	0.137	0	0	0	0	0	1	0	IGHV4-4	immunoglobulin heavy variable 4-4 [Source:HGNC Symbol;Acc:HGNC:5652]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000276903	0	0	0	0	0	0	0	0	0	0	0	0	H2AC16	H2A clustered histone 16 [Source:HGNC Symbol;Acc:HGNC:4730]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000276950	0	0	0	0	0	0	0	0	0	0	0	0	GSTT4	glutathione S-transferase theta 4 [Source:HGNC Symbol;Acc:HGNC:26930]	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Human Diseases;Human Diseases;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Cancer: overview;Cancer: overview;Cancer: overview;Cancer: specific types;Cardiovascular disease;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Drug resistance: antineoplastic;Cancer: overview;Xenobiotics biodegradation and metabolism;Metabolism of other amino acids;Aging	ko01100//Metabolic pathways;ko05200//Pathways in cancer;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko05225//Hepatocellular carcinoma;ko05418//Fluid shear stress and atherosclerosis;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko01524//Platinum drug resistance;ko05204//Chemical carcinogenesis - DNA adducts;ko00982//Drug metabolism - cytochrome P450;ko00480//Glutathione metabolism;ko04212//Longevity regulating pathway - worm	K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799;K00799	GO:0005737//cytoplasm	GO:0004364//glutathione transferase activity;GO:0005515//protein binding;GO:0016740//transferase activity	GO:0006749//glutathione metabolic process	--
ENSG00000276966	0	0.116	0	0	0	0	0	1	0	0	0	0	H4C5	H4 clustered histone 5 [Source:HGNC Symbol;Acc:HGNC:4790]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000277058	0	0	0	0	0	0	0	0	0	0	0	0	HNRNPCL3	heterogeneous nuclear ribonucleoprotein C like 3 [Source:HGNC Symbol;Acc:HGNC:51235]	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12884	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding	-	--
ENSG00000277075	0.663	0.66	0	0.895	0.448	0.26	7	7	0	7	4	2	H2AC8	H2A clustered histone 8 [Source:HGNC Symbol;Acc:HGNC:4724]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0008285//negative regulation of cell population proliferation;GO:0061644//protein localization to CENP-A containing chromatin	--
ENSG00000277117	1.204	1.742	1.772	2.473	2.453	2.084	68.75	117.2	87.89	117.77	139.15	101.81	ICOSLG	"novel protein, similar to inducible T-cell co-stimulator ligand ICOSLG"	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Immune system	ko04514//Cell adhesion molecules;ko04672//Intestinal immune network for IgA production	K06710;K06710	GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0036464//cytoplasmic ribonucleoprotein granule	-	GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0071222//cellular response to lipopolysaccharide	--
ENSG00000277149	2.74	2.388	2.603	2.473	2.208	2.062	158.35	150.25	110.62	114.65	115.13	97	TYW1B	tRNA-yW synthesizing protein 1 homolog B [Source:HGNC Symbol;Acc:HGNC:33908]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0010181//FMN binding;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0102521//tRNA-4-demethylwyosine synthase activity"	GO:0008033//tRNA processing;GO:0031591//wybutosine biosynthetic process	--
ENSG00000277150	2.272	2.598	2.375	1.712	2.644	3.206	80.44	92.46	62.1	44.9	79.09	82.58	F8A3	coagulation factor VIII associated 3 [Source:HGNC Symbol;Acc:HGNC:31850]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0016604//nuclear body	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0099518//vesicle cytoskeletal trafficking;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000277157	0.12	0.119	0.324	0	0	0	1	1	2	0	0	0	H4C4	H4 clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4782]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000277161	3.582	4.204	3.504	3.524	2.958	3.266	198.8	183.7	140.61	140.41	133.14	115.17	PIGW	phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213]	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00563//Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	K05283;K05283	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008374//O-acyltransferase activity;GO:0016740//transferase activity;GO:0016746//acyltransferase activity;GO:0032216//glucosaminyl-phosphatidylinositol O-acyltransferase activity	GO:0006505//GPI anchor metabolic process;GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0072659//protein localization to plasma membrane	--
ENSG00000277200	0.021	0	0.07	0	0	0	2	0	5	0	0	0	CCDC92B	coiled-coil domain containing 92B [Source:HGNC Symbol;Acc:HGNC:52279]	-	-	-	-	-	-	-	--
ENSG00000277224	0	0	0	0	0	0	0	0	0	0	0	0	H2BC7	H2B clustered histone 7 [Source:HGNC Symbol;Acc:HGNC:4752]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000277258	20.507	18.382	19.655	24.434	24.06	21.843	919.87	864.06	682.84	829.24	893.45	739.36	PCGF2	polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929]	Cellular Processes	Cellular community - eukaryotes	ko04550//Signaling pathways regulating pluripotency of stem cells	K11460	GO:0000785//chromatin;GO:0001739//sex chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex	GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:1990841//promoter-specific chromatin binding	GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0001701//in utero embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0016573//histone acetylation;GO:0036353//histone H2A-K119 monoubiquitination;GO:0048704//embryonic skeletal system morphogenesis;GO:0048706//embryonic skeletal system development;GO:0070301//cellular response to hydrogen peroxide;GO:2001234//negative regulation of apoptotic signaling pathway	--
ENSG00000277277	0.803	0.799	0.645	0.373	0.742	0.689	16	16	9.5	5.5	12.5	10	FAM243A	novel protein identical to C21orf140	-	-	-	-	-	-	-	--
ENSG00000277282	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1OR21-1	immunoglobulin heavy variable 1/OR21-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:38040]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000277322	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L6	golgin A6 family like 6 [Source:HGNC Symbol;Acc:HGNC:37225]	-	-	-	-	-	-	-	--
ENSG00000277363	1.654	1.768	2.166	2.051	2.471	1.994	117	133	108	99	156	99	SRCIN1	SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506]	-	-	-	-	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0030054//cell junction;GO:0030175//filopodium;GO:0030424//axon;GO:0030425//dendrite;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0098793//presynapse;GO:0098794//postsynapse;GO:0110165//cellular anatomical entity	GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019904//protein domain specific binding	GO:0006887//exocytosis;GO:0030334//regulation of cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050709//negative regulation of protein secretion;GO:0061001//regulation of dendritic spine morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000277399	0.011	0.021	0.007	0.007	0.012	0	2	4	1	1	2	0	GPR179	G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0044292//dendrite terminus	GO:0004930//G protein-coupled receptor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0072659//protein localization to plasma membrane	--
ENSG00000277443	21.693	20.946	19.86	19.786	19.261	23.012	1933	1876	1307	1306	1450	1492	MARCKS	myristoylated alanine rich protein kinase C substrate [Source:HGNC Symbol;Acc:HGNC:6759]	Human Diseases;Organismal Systems	Cancer: overview;Immune system	ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis	K12561;K12561	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0032432//actin filament bundle;GO:0042585//germinal vesicle;GO:0070062//extracellular exosome	GO:0003779//actin binding;GO:0005080//protein kinase C binding;GO:0005516//calmodulin binding;GO:0042802//identical protein binding;GO:0051015//actin filament binding	GO:0007015//actin filament organization;GO:0007417//central nervous system development;GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation	--
ENSG00000277462	1.183	1.051	1.275	1.272	0.897	1.058	103	92	82	82	66	67	ZNF670	zinc finger protein 670 [Source:HGNC Symbol;Acc:HGNC:28167]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006629//lipid metabolic process;GO:0044255//cellular lipid metabolic process"	zf-C2H2
ENSG00000277481	0.086	0.034	0.023	0.081	0.03	0.118	10	4	2	7	3	10	PKD1L3	"polycystin 1 like 3, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:21716]"	Organismal Systems	Sensory system	ko04742//Taste transduction	K04989	GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034703//cation channel complex;GO:0043235//receptor complex;GO:0070062//extracellular exosome	GO:0005261//cation channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0008324//cation transmembrane transporter activity;GO:0030246//carbohydrate binding;GO:0033040//sour taste receptor activity	GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0001822//kidney development;GO:0006811//ion transport;GO:0006812//cation transport;GO:0006816//calcium ion transport;GO:0050915//sensory perception of sour taste;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport;GO:0071468//cellular response to acidic pH	--
ENSG00000277494	0	0	0	0	0	0	0	0	0	0	0	0	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 [Source:HGNC Symbol;Acc:HGNC:24945]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0031362//anchored component of external side of plasma membrane;GO:1902494//catalytic complex	GO:0005515//protein binding;GO:0008289//lipid binding;GO:0035473//lipase binding;GO:0035478//chylomicron binding;GO:0060230//lipoprotein lipase activator activity;GO:0071813//lipoprotein particle binding;GO:0140318//protein transporter activity	GO:0006886//intracellular protein transport;GO:0017038//protein import;GO:0019433//triglyceride catabolic process;GO:0034394//protein localization to cell surface;GO:0042632//cholesterol homeostasis;GO:0045056//transcytosis;GO:0050821//protein stabilization;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0070328//triglyceride homeostasis;GO:0071503//response to heparin;GO:0090321//positive regulation of chylomicron remnant clearance	--
ENSG00000277531	0.239	0.441	0.4	0.154	0.067	0.125	21	39	26	10	5	8	PNMA8C	PNMA family member 8C [Source:HGNC Symbol;Acc:HGNC:53427]	-	-	-	-	-	-	-	--
ENSG00000277535	0	0	0	0	0	0	0	0	0	0	0	0	CT47A1	novel cancer/testis antigen family protein	-	-	-	-	-	-	-	--
ENSG00000277556	0	0	0	0	0	0	0	0	0	0	0	0	OR13C5	olfactory receptor family 13 subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:15100]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000277586	0.027	0	0	0.018	0	0	2	0	0	1	0	0	NEFL	neurofilament light chain [Source:HGNC Symbol;Acc:HGNC:7739]	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05014//Amyotrophic lateral sclerosis	K04572;K04572	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005882//intermediate filament;GO:0005883//neurofilament;GO:0030424//axon;GO:0030426//growth cone;GO:0031594//neuromuscular junction;GO:0042995//cell projection;GO:0043005//neuron projection;GO:0098685//Schaffer collateral - CA1 synapse;GO:0098981//cholinergic synapse;GO:0099160//postsynaptic intermediate filament cytoskeleton;GO:0099182//presynaptic intermediate filament cytoskeleton;GO:1904115//axon cytoplasm	GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0030674//protein-macromolecule adaptor activity;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0044877//protein-containing complex binding;GO:0099184//structural constituent of postsynaptic intermediate filament cytoskeleton	GO:0000226//microtubule cytoskeleton organization;GO:0008089//anterograde axonal transport;GO:0008090//retrograde axonal transport;GO:0009636//response to toxic substance;GO:0010033//response to organic substance;GO:0014012//peripheral nervous system axon regeneration;GO:0019896//axonal transport of mitochondrion;GO:0021510//spinal cord development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0031133//regulation of axon diameter;GO:0033693//neurofilament bundle assembly;GO:0040011//locomotion;GO:0043434//response to peptide hormone;GO:0043524//negative regulation of neuron apoptotic process;GO:0045105//intermediate filament polymerization or depolymerization;GO:0045109//intermediate filament organization;GO:0045110//intermediate filament bundle assembly;GO:0048812//neuron projection morphogenesis;GO:0050772//positive regulation of axonogenesis;GO:0050885//neuromuscular process controlling balance;GO:0051258//protein polymerization;GO:0051412//response to corticosterone;GO:0060052//neurofilament cytoskeleton organization;GO:0060074//synapse maturation;GO:0061564//axon development;GO:0099185//postsynaptic intermediate filament cytoskeleton organization;GO:1903935//response to sodium arsenite;GO:1903937//response to acrylamide	--
ENSG00000277611	0	0	0	0	0	0	0	0	0	0	0	0	L3MBTL1	novel protein	-	-	-	-	GO:0005634//nucleus	GO:0003682//chromatin binding;GO:0042393//histone binding	"GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000277632	0	0	0	0	0.073	0	0	0	0	0	1	0	CCL3	C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627]	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune system;Immune disease;Infectious disease: parasitic;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko05163//Human cytomegalovirus infection;ko05417//Lipid and atherosclerosis;ko04062//Chemokine signaling pathway;ko05323//Rheumatoid arthritis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K05408;K05408;K05408;K05408;K05408;K05408;K05408;K05408	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005829//cytosol	GO:0004672//protein kinase activity;GO:0004698//calcium-dependent protein kinase C activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0008009//chemokine activity;GO:0016004//phospholipase activator activity;GO:0016301//kinase activity;GO:0031726//CCR1 chemokine receptor binding;GO:0031730//CCR5 chemokine receptor binding;GO:0042056//chemoattractant activity;GO:0042802//identical protein binding;GO:0048020//CCR chemokine receptor binding	GO:0000165//MAPK cascade;GO:0001649//osteoblast differentiation;GO:0001775//cell activation;GO:0002548//monocyte chemotaxis;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0009636//response to toxic substance;GO:0010628//positive regulation of gene expression;GO:0010629//negative regulation of gene expression;GO:0010818//T cell chemotaxis;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0016310//phosphorylation;GO:0019722//calcium-mediated signaling;GO:0023052//signaling;GO:0030335//positive regulation of cell migration;GO:0030502//negative regulation of bone mineralization;GO:0030593//neutrophil chemotaxis;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043308//eosinophil degranulation;GO:0043491//protein kinase B signaling;GO:0043525//positive regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0043615//astrocyte cell migration;GO:0043922//negative regulation by host of viral transcription;GO:0045671//negative regulation of osteoclast differentiation;GO:0048245//eosinophil chemotaxis;GO:0048246//macrophage chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0050795//regulation of behavior;GO:0050850//positive regulation of calcium-mediated signaling;GO:0050918//positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0051928//positive regulation of calcium ion transport;GO:0051930//regulation of sensory perception of pain;GO:0060326//cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070723//response to cholesterol;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0071407//cellular response to organic cyclic compound;GO:0071621//granulocyte chemotaxis;GO:0090280//positive regulation of calcium ion import;GO:1903980//positive regulation of microglial cell activation;GO:1904141//positive regulation of microglial cell migration;GO:2000503//positive regulation of natural killer cell chemotaxis	--
ENSG00000277639	0.686	0.626	0.387	0.27	0.101	0.353	24	22	10	7	3	9	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000277734	0.246	0.098	0.067	0.067	0.117	0	5	2	1	1	2	0	TRAC	T cell receptor alpha constant [Source:HGNC Symbol;Acc:HGNC:12029]	Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Cancer: overview;Signal transduction;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune disease;Infectious disease: bacterial;Signal transduction;Infectious disease: bacterial;Immune disease;Signaling molecules and interaction;Infectious disease: viral;Cardiovascular disease;Immune disease;Immune system;Immune system;Immune system;Immune disease;Infectious disease: parasitic;Immune disease;Immune system;Cancer: overview;Immune system;Immune disease;Infectious disease: parasitic;Endocrine and metabolic disease;Immune disease	ko04020//Calcium signaling pathway;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko04014//Ras signaling pathway;ko05166//Human T-cell leukemia virus 1 infection;ko04015//Rap1 signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04064//NF-kappa B signaling pathway;ko05150//Staphylococcus aureus infection;ko05323//Rheumatoid arthritis;ko04514//Cell adhesion molecules;ko05162//Measles;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko04672//Intestinal immune network for IgA production;ko04659//Th17 cell differentiation;ko04660//T cell receptor signaling pathway;ko05330//Allograft rejection;ko05142//Chagas disease;ko05310//Asthma;ko04658//Th1 and Th2 cell differentiation;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04612//Antigen processing and presentation;ko05321//Inflammatory bowel disease;ko05144//Malaria;ko04940//Type I diabetes mellitus;ko05332//Graft-versus-host disease	K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784;K10784	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000277745	0	0	0	0	0	0	0	0	0	0	0	0	H2AB3	H2A.B variant histone 3 [Source:HGNC Symbol;Acc:HGNC:14455]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0035327//transcriptionally active chromatin	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly;GO:0006397//mRNA processing	--
ENSG00000277758	0.227	0.499	0.137	0.269	0.259	0.11	54.97	58	21.25	48.3	53.08	19.38	SYT15	novel protein identical to synaptotagmin XV	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000277775	0	0	0	0	0	0	0	0	0	0	0	0	H3C7	H3 clustered histone 7 [Source:HGNC Symbol;Acc:HGNC:4773]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000277791	66.617	70.025	70.909	69.782	64.905	63.689	1048	1106	824	814	855	730	PSMB3	proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Genetic Information Processing	"Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Folding, sorting and degradation"	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko05017//Spinocerebellar ataxia;ko03050//Proteasome	K02735;K02735;K02735;K02735;K02735;K02735;K02735;K02735	"GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0019774//proteasome core complex, beta-subunit complex;GO:0070062//extracellular exosome"	GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding	"GO:0000165//MAPK cascade;GO:0000209//protein polyubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010498//proteasomal protein catabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0016579//protein deubiquitination;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0036388//pre-replicative complex assembly;GO:0038061//NIK/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043488//regulation of mRNA stability;GO:0043687//post-translational protein modification;GO:0050852//T cell receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0055085//transmembrane transport;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0070498//interleukin-1-mediated signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1902036//regulation of hematopoietic stem cell differentiation"	--
ENSG00000277858	0	0	0	0	0	0	0	0	0	0	0	0	H2AB2	H2A.B variant histone 2 [Source:HGNC Symbol;Acc:HGNC:18298]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0035327//transcriptionally active chromatin	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly;GO:0006397//mRNA processing	--
ENSG00000277865	0	0	0	0	0	0	0	0	0	0	0	0	GOLGA6L22	golgin A6 family like 22 [Source:HGNC Symbol;Acc:HGNC:50289]	-	-	-	-	-	-	-	--
ENSG00000277893	0.011	0	0	0	0	0	1	0	0	0	0	0	SRD5A2	steroid 5 alpha-reductase 2 [Source:HGNC Symbol;Acc:HGNC:11285]	Metabolism;Human Diseases;Metabolism	Global and overview maps;Cancer: specific types;Lipid metabolism	ko01100//Metabolic pathways;ko05215//Prostate cancer;ko00140//Steroid hormone biosynthesis	K12344;K12344;K12344	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0070852//cell body fiber	"GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0005515//protein binding;GO:0009917//sterol 5-alpha reductase activity;GO:0016491//oxidoreductase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0033218//amide binding;GO:0047751//cholestenone 5-alpha-reductase activity"	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006702//androgen biosynthetic process;GO:0006706//steroid catabolic process;GO:0007267//cell-cell signaling;GO:0007548//sex differentiation;GO:0008202//steroid metabolic process;GO:0008209//androgen metabolic process;GO:0008584//male gonad development;GO:0009410//response to xenobiotic stimulus;GO:0010033//response to organic substance;GO:0014070//response to organic cyclic compound;GO:0018879//biphenyl metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0018963//phthalate metabolic process;GO:0021766//hippocampus development;GO:0021854//hypothalamus development;GO:0030154//cell differentiation;GO:0030539//male genitalia development;GO:0030540//female genitalia development;GO:0031667//response to nutrient levels;GO:0032354//response to follicle-stimulating hormone;GO:0033574//response to testosterone;GO:0043434//response to peptide hormone;GO:0048545//response to steroid hormone;GO:0060348//bone development;GO:0061370//testosterone biosynthetic process	--
ENSG00000277932	0	0	0	0	0	0	0	0	0	0	0	0	OR52E5	olfactory receptor family 52 subfamily E member 5 [Source:HGNC Symbol;Acc:HGNC:15214]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000277957	0.084	0	0.306	0.121	0	0.346	6.11	0	16.5	6.56	0	18.4	SENP3-EIF4A1	SENP3-EIF4A1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49182]	-	-	-	-	GO:0005634//nucleus;GO:0071339//MLL1 complex	GO:0008234//cysteine-type peptidase activity	GO:0006508//proteolysis;GO:0016926//protein desumoylation	--
ENSG00000277971	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex	-	GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0051301//cell division	--
ENSG00000277972	4.234	3.814	4.992	3.488	3.836	4.249	224.13	202.94	195.16	136.76	171.55	163.64	CISD3	CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578]	-	-	-	-	GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle	"GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051537//2 iron, 2 sulfur cluster binding"	GO:0106034//protein maturation by [2Fe-2S] cluster transfer	--
ENSG00000278023	0.179	0.684	0.45	0	0.073	0	4	8	6	0	1	0	RDM1	RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0016605//PML body	GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding	GO:0006259//DNA metabolic process	--
ENSG00000278053	7.23	5.567	5.415	4.623	4.874	5.478	552	472	321	258	328	285	DDX52	DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity	GO:0030490//maturation of SSU-rRNA	--
ENSG00000278057	0	0	0	0	0	0	0	0	0	0	0	0	TEX28	testis expressed 28 [Source:HGNC Symbol;Acc:HGNC:2563]	-	-	-	-	GO:0012505//endomembrane system;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0008150//biological_process	--
ENSG00000278085	0	0	0	0	0	0	0	0	0	0	0	0	CT45A8	cancer/testis antigen family 45 member A8 [Source:HGNC Symbol;Acc:HGNC:51261]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000278129	1.246	1.23	1.456	1.102	1.13	1.548	235.38	233.67	203.23	154.24	180.43	212.88	ZNF8	zinc finger protein 8 [Source:HGNC Symbol;Acc:HGNC:13154]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0030509//BMP signaling pathway"	zf-C2H2
ENSG00000278139	0	0	0	0	0	0	0	0	0	0	0	0	P3R3URF-PIK3R3	P3R3URF-PIK3R3 readthrough [Source:HGNC Symbol;Acc:HGNC:54999]	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Cancer: overview;Signal transduction;Neurodegenerative disease;Infectious disease: viral;Infectious disease: viral;Neurodegenerative disease;Infectious disease: viral;Immune system;Infectious disease: bacterial;Signal transduction;Cancer: overview;Infectious disease: viral;Infectious disease: viral;Signal transduction;Cell motility;Signal transduction;Signal transduction;Infectious disease: viral;Cardiovascular disease;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Infectious disease: viral;Immune system;Immune system;Development and regeneration;Infectious disease: viral;Infectious disease: parasitic;Cancer: overview;Immune system;Signal transduction;Endocrine and metabolic disease;Cancer: specific types;Infectious disease: viral;Signal transduction;Cell growth and death;Infectious disease: viral;Transport and catabolism;Immune system;Cancer: specific types;Cancer: specific types;Infectious disease: viral;Neurodegenerative disease;Cellular community - eukaryotes;Endocrine system;Cell growth and death;Cardiovascular disease;Endocrine system;Immune system;Signal transduction;Endocrine system;Development and regeneration;Immune system;Endocrine system;Nervous system;Signal transduction;Signal transduction;Endocrine system;Signal transduction;Immune system;Nervous system;Endocrine system;Signal transduction;Endocrine and metabolic disease;Immune system;Infectious disease: parasitic;Immune system;Immune system;Cancer: overview;Endocrine and metabolic disease;Cancer: specific types;Drug resistance: antineoplastic;Sensory system;Signal transduction;Cancer: overview;Aging;Cancer: specific types;Cancer: specific types;Signal transduction;Drug resistance: antineoplastic;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cancer: specific types;Endocrine system;Cancer: specific types;Cancer: specific types;Cancer: specific types;Cancer: overview;Drug resistance: antineoplastic;Cancer: specific types;Aging;Endocrine system;Signal transduction;Endocrine system;Cancer: specific types;Endocrine and metabolic disease;Digestive system;Excretory system	"ko05168//Herpes simplex virus 1 infection;ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko05165//Human papillomavirus infection;ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05169//Epstein-Barr virus infection;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko04014//Ras signaling pathway;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05163//Human cytomegalovirus infection;ko05166//Human T-cell leukemia virus 1 infection;ko04024//cAMP signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05170//Human immunodeficiency virus 1 infection;ko05415//Diabetic cardiomyopathy;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05207//Chemical carcinogenesis - receptor activation;ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04062//Chemokine signaling pathway;ko04650//Natural killer cell mediated cytotoxicity;ko04360//Axon guidance;ko05164//Influenza A;ko05146//Amoebiasis;ko05206//MicroRNAs in cancer;ko04666//Fc gamma R-mediated phagocytosis;ko04630//JAK-STAT signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko05225//Hepatocellular carcinoma;ko05161//Hepatitis B;ko04150//mTOR signaling pathway;ko04218//Cellular senescence;ko05160//Hepatitis C;ko04140//Autophagy - animal;ko04662//B cell receptor signaling pathway;ko05224//Breast cancer;ko05226//Gastric cancer;ko05162//Measles;ko05017//Spinocerebellar ataxia;ko04550//Signaling pathways regulating pluripotency of stem cells;ko04910//Insulin signaling pathway;ko04210//Apoptosis;ko05418//Fluid shear stress and atherosclerosis;ko04915//Estrogen signaling pathway;ko04664//Fc epsilon RI signaling pathway;ko04068//FoxO signaling pathway;ko04926//Relaxin signaling pathway;ko04380//Osteoclast differentiation;ko04611//Platelet activation;ko04919//Thyroid hormone signaling pathway;ko04722//Neurotrophin signaling pathway;ko04152//AMPK signaling pathway;ko04071//Sphingolipid signaling pathway;ko04935//Growth hormone synthesis, secretion and action;ko04066//HIF-1 signaling pathway;ko04670//Leukocyte transendothelial migration;ko04725//Cholinergic synapse;ko04914//Progesterone-mediated oocyte maturation;ko04668//TNF signaling pathway;ko04931//Insulin resistance;ko04660//T cell receptor signaling pathway;ko05142//Chagas disease;ko04625//C-type lectin receptor signaling pathway;ko04620//Toll-like receptor signaling pathway;ko05231//Choline metabolism in cancer;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko05215//Prostate cancer;ko01522//Endocrine resistance;ko04750//Inflammatory mediator regulation of TRP channels;ko04070//Phosphatidylinositol signaling system;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko04211//Longevity regulating pathway;ko05210//Colorectal cancer;ko05222//Small cell lung cancer;ko04012//ErbB signaling pathway;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05214//Glioma;ko05220//Chronic myeloid leukemia;ko04917//Prolactin signaling pathway;ko05211//Renal cell carcinoma;ko05218//Melanoma;ko05223//Non-small cell lung cancer;ko05230//Central carbon metabolism in cancer;ko01524//Platinum drug resistance;ko05221//Acute myeloid leukemia;ko04213//Longevity regulating pathway - multiple species;ko04929//GnRH secretion;ko04370//VEGF signaling pathway;ko04923//Regulation of lipolysis in adipocytes;ko05213//Endometrial cancer;ko04930//Type II diabetes mellitus;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption"	K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649;K02649	-	-	-	--
ENSG00000278195	0	0	0.037	0	0	0	0	0	1	0	0	0	SSTR3	somatostatin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11332]	Environmental Information Processing;Organismal Systems	Signaling molecules and interaction;Endocrine system	"ko04080//Neuroactive ligand-receptor interaction;ko04935//Growth hormone synthesis, secretion and action"	K04219;K04219	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0060170//ciliary membrane;GO:0097730//non-motile cilium	GO:0004930//G protein-coupled receptor activity;GO:0004994//somatostatin receptor activity;GO:0005102//signaling receptor binding;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	"GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007187//G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0021549//cerebellum development;GO:0030900//forebrain development;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus"	--
ENSG00000278196	0	0	0	0	0	0	0	0	0	0	0	0	IGLV2-8	immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000278224	0.295	0.211	0.23	0.178	0.421	0.425	8.53	5.9	7.39	5.73	15.48	11.65	PRICKLE4	prickle planar cell polarity protein 4 [Source:HGNC Symbol;Acc:HGNC:16805]	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K04511	GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0030018//Z disc;GO:0031941//filamentous actin	GO:0003674//molecular_function;GO:0003779//actin binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0051371//muscle alpha-actinin binding	GO:0007507//heart development;GO:0008150//biological_process;GO:0030036//actin cytoskeleton organization;GO:0061061//muscle structure development	--
ENSG00000278259	4.743	6.332	5.746	3.414	3.826	5.298	316.2	368.3	266.39	169.59	244.86	241.83	MYO19	myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234]	-	-	-	-	GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0016459//myosin complex;GO:0031982//vesicle	GO:0000146//microfilament motor activity;GO:0000166//nucleotide binding;GO:0003774//cytoskeletal motor activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0032027//myosin light chain binding;GO:0051015//actin filament binding;GO:0060002//plus-end directed microfilament motor activity	GO:0007015//actin filament organization;GO:0030050//vesicle transport along actin filament;GO:0032465//regulation of cytokinesis;GO:0034642//mitochondrion migration along actin filament;GO:0090140//regulation of mitochondrial fission	--
ENSG00000278263	0	0	0	0	0	0	0	0	0	0	0	0	IGHV4-4	"novel protein, identical to IGHV4-4"	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000278289	0	0	0	0	0	0	0	0	0	0	0	0	CT45A6	cancer/testis antigen family 45 member A6 [Source:HGNC Symbol;Acc:HGNC:33271]	-	-	-	-	GO:0032039//integrator complex	-	GO:0034472//snRNA 3'-end processing	--
ENSG00000278299	1.058	0.991	0.601	1.434	1.907	1.538	46.21	43.51	19.38	46.37	70.34	48.86	TBC1D3C	TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000278311	13.475	12.228	11.422	10.187	11.49	12.522	734	702	481	408	493	522	GGNBP2	gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle	-	GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell population proliferation;GO:0010629//negative regulation of gene expression;GO:0030154//cell differentiation;GO:0033140//negative regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0060711//labyrinthine layer development;GO:0060716//labyrinthine layer blood vessel development;GO:0061099//negative regulation of protein tyrosine kinase activity	--
ENSG00000278318	5.723	4.601	3.265	3.538	3.471	5.04	366	360	260	197	296	277	ZNF229	zinc finger protein 229 [Source:HGNC Symbol;Acc:HGNC:13022]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0045944//positive regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000278463	0	0	0	0	0	0	0	0	0	0	0	0	H2AC4	H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0006333//chromatin assembly or disassembly;GO:0008285//negative regulation of cell population proliferation;GO:0061644//protein localization to CENP-A containing chromatin	--
ENSG00000278505	0	0	0	0	0	0	0	0	0	0	0	0	C17orf78	chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000278522	0	0	0	0	0	0	0	0	0	0	0	0	POTEB3	POTE ankyrin domain family member B3 [Source:HGNC Symbol;Acc:HGNC:51240]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000278535	5.589	5.593	5.428	6.018	6.102	5.054	156	167	115	134	145	114	DHRS11	dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639]	Metabolism	Lipid metabolism	ko00140//Steroid hormone biosynthesis	K22970	GO:0005575//cellular_component;GO:0005576//extracellular region	GO:0000166//nucleotide binding;GO:0000253//3-keto sterol reductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0072555//17-beta-ketosteroid reductase activity;GO:0072582//17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0102176//cycloeucalenone reductase activity	GO:0006629//lipid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008202//steroid metabolic process	--
ENSG00000278540	21.235	20.875	21.61	18.115	19.185	20.284	3726	3421	2614	2118	2715	2492	ACACA	acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84]	Metabolism;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Endocrine and metabolic disease;Endocrine system;Signal transduction;Endocrine system;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Lipid metabolism	ko01100//Metabolic pathways;ko04936//Alcoholic liver disease;ko04910//Insulin signaling pathway;ko04152//AMPK signaling pathway;ko04922//Glucagon signaling pathway;ko01212//Fatty acid metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism;ko00061//Fatty acid biosynthesis	K11262;K11262;K11262;K11262;K11262;K11262;K11262;K11262;K11262	GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton	GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0003989//acetyl-CoA carboxylase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding	GO:0001894//tissue homeostasis;GO:0006084//acetyl-CoA metabolic process;GO:0006629//lipid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0008152//metabolic process;GO:0019538//protein metabolic process;GO:0043603//cellular amide metabolic process;GO:0044281//small molecule metabolic process;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0051289//protein homotetramerization;GO:0055088//lipid homeostasis;GO:0071380//cellular response to prostaglandin E stimulus;GO:2001295//malonyl-CoA biosynthetic process	--
ENSG00000278558	0.472	0.557	0.145	0.498	0.719	0.679	13.05	15.48	2.97	10.2	16.8	13.68	TMEM191B	transmembrane protein 191B [Source:HGNC Symbol;Acc:HGNC:33600]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000278570	0	0	0.033	0	0	0	0	0	1	0	0	0	NR2E3	nuclear receptor subfamily 2 group E member 3 [Source:HGNC Symbol;Acc:HGNC:7974]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription regulator complex	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228//DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0008285//negative regulation of cell population proliferation;GO:0010628//positive regulation of gene expression;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0042462//eye photoreceptor cell development;GO:0043401//steroid hormone mediated signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0048856//anatomical structure development;GO:0050896//response to stimulus;GO:0060041//retina development in camera-type eye"	RXR-like
ENSG00000278588	0	0	0	0	0	0	0	0	0	0	0	0	H2BC10	H2B clustered histone 10 [Source:HGNC Symbol;Acc:HGNC:4756]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity	GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0050830//defense response to Gram-positive bacterium;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide	--
ENSG00000278599	0	0.103	0	0	0	0	0	4.48	0	0	0	0	TBC1D3E	TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane	GO:0005096//GTPase activator activity	GO:0090630//activation of GTPase activity	--
ENSG00000278615	23.28	23.648	29.504	27.903	25.748	26.015	311.94	318.5	291.98	276.95	287.9	253.63	C11orf98	chromosome 11 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:51238]	-	-	-	-	-	-	-	--
ENSG00000278619	1.232	1.408	1.207	1.699	0.9	1.729	47	54	34	48	29	48	MRM1	mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix	GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0016740//transferase activity;GO:0070039//rRNA (guanosine-2'-O-)-methyltransferase activity	GO:0000451//rRNA 2'-O-methylation;GO:0001510//RNA methylation;GO:0006364//rRNA processing;GO:0006396//RNA processing;GO:0032259//methylation	--
ENSG00000278637	0	0	0	0	0	0	0	0	0	0	0	0	H4C1	H4 clustered histone 1 [Source:HGNC Symbol;Acc:HGNC:4781]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000278646	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)"	-	-	-	-	-	-	-	--
ENSG00000278661	0	0	0	0	0	0	0	0	0	0	0	0	TRAJ37	T cell receptor alpha joining 37 [Source:HGNC Symbol;Acc:HGNC:12067]	-	-	-	-	-	-	-	--
ENSG00000278662	0.047	0.132	0.137	0.156	0.072	0.136	4.05	11.41	8.7	10.7	5.65	8.53	GOLGA6L10	golgin A6 family like 10 [Source:HGNC Symbol;Acc:HGNC:37228]	-	-	-	-	-	-	-	--
ENSG00000278677	0	0.098	0	0	0	0	0	1	0	0	0	0	H2AC17	H2A clustered histone 17 [Source:HGNC Symbol;Acc:HGNC:4735]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000278685	0	0	0	0	0	0	0	0	0	0	0	0	IQCA1L	IQ motif containing with AAA domain 1 like [Source:HGNC Symbol;Acc:HGNC:22831]	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity	-	--
ENSG00000278705	0	0	0	0	0.147	0	0	0	0	0	1	0	H4C2	H4 clustered histone 2 [Source:HGNC Symbol;Acc:HGNC:4789]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11254;K11254;K11254;K11254	"GO:0000228//nuclear chromosome;GO:0000781//chromosome, telomeric region;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0043505//CENP-A containing nucleosome;GO:0070062//extracellular exosome"	GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032200//telomere organization;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0061644//protein localization to CENP-A containing chromatin"	--
ENSG00000278803	0	0	0	0	0	0	0	0	0	0	0	0	PWWP4	PWWP domain containing 4 [Source:HGNC Symbol;Acc:HGNC:55197]	-	-	-	-	-	-	-	--
ENSG00000278828	0.534	0.75	0.418	0.417	0.608	0.387	8	12	8	8	6	5	H3C10	H3 clustered histone 10 [Source:HGNC Symbol;Acc:HGNC:4775]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000278845	24.059	26.499	26.186	25.103	25.905	22.655	775	858	623	599	705	531	MRPL45	mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651]	-	-	-	-	GO:0005739//mitochondrion	-	-	--
ENSG00000278848	0	0	0	0	0	0	0	0	0	0	0	0	TP53TG3F	TP53 target 3 family member F [Source:HGNC Symbol;Acc:HGNC:51817]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	-	-	--
ENSG00000278857	0	0	0	0	0	0	0	0	0	0	0	0	IGKV1D-12	immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746]	-	-	-	-	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0070062//extracellular exosome;GO:0072562//blood microparticle	GO:0003823//antigen binding	GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006955//immune response	--
ENSG00000278870	0	0	0	0	0	0	0	0	0	0	0	0	OR51G1	olfactory receptor family 51 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:14738]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000278889	0	0	0	0	0	0	0	0	0	0	0	0	OR2S2	olfactory receptor family 2 subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:8276]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000278961	0	0.132	0	0	0	0	0	4	0	0	0	0	SMIM34A	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000279000	0	0	0.011	0	0.019	0	0	0	1	0	2	0	OR10A6	olfactory receptor family 10 subfamily A member 6 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15132]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279012	0	0	0	0	0	0	0	0	0	0	0	0	OR51B2	olfactory receptor family 51 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:14703]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279051	0	0	0	0	0	0	0	0	0	0	0	0	OR6Q1	olfactory receptor family 6 subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:15302]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279073	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000279111	0	0	0	0	0	0	0	0	0	0	0	0	OR10X1	olfactory receptor family 10 subfamily X member 1 [Source:HGNC Symbol;Acc:HGNC:14995]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279116	0	0	0	0	0	0	0	0	0	0	0	0	OR8D2	olfactory receptor family 8 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8482]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279169	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF13	PRAME family member 13 [Source:HGNC Symbol;Acc:HGNC:13262]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000279170	0.154	0.461	1.773	0.876	0.708	0.819	6	18	11	10	7	12	TSTD3	thiosulfate sulfurtransferase like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:40910]	-	-	-	-	-	-	-	--
ENSG00000279263	0	0	0	0	0	0	0	0	0	0	0	0	OR2L8	olfactory receptor family 2 subfamily L member 8 [Source:HGNC Symbol;Acc:HGNC:15014]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003674//molecular_function;GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0008150//biological_process;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279270	0	0	0	0	0	0	0	0	0	0	0	0	OR52R1	olfactory receptor family 52 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:15235]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279301	0	0	0	0	0	0	0	0	0	0	0	0	OR2T11	olfactory receptor family 2 subfamily T member 11 [Source:HGNC Symbol;Acc:HGNC:19574]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279395	0	0	0	0	0	0	0	0	0	0	0	0	OR5L1	olfactory receptor family 5 subfamily L member 1 [Source:HGNC Symbol;Acc:HGNC:8350]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279408	0	0	0	0	0	0	0	0	0	0	0	0	OR4N4C	olfactory receptor family 4 subfamily N member 4C [Source:HGNC Symbol;Acc:HGNC:55110]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279486	0	0	0	0	0	0	0	0	0	0	0	0	OR2AG1	olfactory receptor family 2 subfamily AG member 1 [Source:HGNC Symbol;Acc:HGNC:15142]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279493	0	0	0	0	0	0	0	0	0	0	0	0	DNMT3L	"novel protein, similar to DNA (cytosine-5-)-methyltransferase 3-like DNMT3L"	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0030234//enzyme regulator activity	"GO:0006306//DNA methylation;GO:0032776//DNA methylation on cytosine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050790//regulation of catalytic activity"	--
ENSG00000279514	0	0	0	0	0	0	0	0	0	0	0	0	OR4C16	olfactory receptor family 4 subfamily C member 16 [Source:HGNC Symbol;Acc:HGNC:15172]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279686	0	0	0	0	0	0	0	0	0	0	0	0	ECSCR	novel transcript	-	-	-	-	-	-	-	--
ENSG00000279761	0	0	0	0	0	0	0	0	0	0	0	0	OR5D13	olfactory receptor family 5 subfamily D member 13 [Source:HGNC Symbol;Acc:HGNC:15280]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279765	0.834	0.82	0.792	0.912	0.514	0	13.97	13.82	9.8	11.32	7.28	0	CHD2	novel protein	-	-	-	-	-	-	-	--
ENSG00000279782	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4F	peptidylprolyl isomerase A like 4F [Source:HGNC Symbol;Acc:HGNC:33999]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000279804	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF18	PRAME family member 18 [Source:HGNC Symbol;Acc:HGNC:30693]	-	-	-	-	GO:0005737//cytoplasm	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000279956	0	0	0	0	0.027	0	0	0	0	0	1	0	LHCGR	novel transcript	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Signal transduction;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04024//cAMP signaling pathway;ko04917//Prolactin signaling pathway;ko04913//Ovarian steroidogenesis	K04248;K04248;K04248;K04248;K04248	GO:0016021//integral component of membrane	GO:0004964//luteinizing hormone receptor activity	GO:0007186//G protein-coupled receptor signaling pathway;GO:0042700//luteinizing hormone signaling pathway	--
ENSG00000279961	0	0	0	0	0	0	0	0	0	0	0	0	OR8U3	olfactory receptor family 8 subfamily U member 3 [Source:HGNC Symbol;Acc:HGNC:14841]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000279983	0	0	0	0	0.104	0	0	0	0	0	1	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000280021	0	0	0	0	0	0	0	0	0	0	0	0	OR51F1	olfactory receptor family 51 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:15196]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280071	22.951	23.195	25.346	25.062	25.524	22.007	696.69	704.58	569.83	585.5	639.18	479.11	GATD3B	"novel protein, similar to chromosome 21 open reading frame 33 C21orf33"	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	-	--
ENSG00000280090	0	0	0	0	0	0	0	0	0	0	0	0	OR8B4	olfactory receptor family 8 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:8473]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280094	0	0	0	0	0	0	0	0	0	0	0	0	OR1B1	olfactory receptor family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:8181]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280148	0	0	0	0	0	0	0	0	0	0	0	0	LTV1	novel transcript	-	-	-	-	-	-	GO:0042274//ribosomal small subunit biogenesis	--
ENSG00000280165	0.464	0.241	0.15	0.368	0.43	0.402	46	24	11	27	36	29	PCDH20	protocadherin 20 [Source:HGNC Symbol;Acc:HGNC:14257]	-	-	-	-	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003723//RNA binding;GO:0005509//calcium ion binding	GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules	--
ENSG00000280204	0	0	0	0	0	0	0	0	0	0	0	0	OR1S1	olfactory receptor family 1 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:8227]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280236	0	0	0	0	0	0	0	0	0	0	0	0	OR12D2	olfactory receptor family 12 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8178]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280267	0	0	0	0	0	0	0	0	0	0	0	0	PRAMEF26	PRAME family member 26 [Source:HGNC Symbol;Acc:HGNC:49178]	-	-	-	-	-	-	"GO:0008284//positive regulation of cell population proliferation;GO:0043066//negative regulation of apoptotic process;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated"	--
ENSG00000280314	0	0	0	0	0	0	0	0	0	0	0	0	OR8K3	olfactory receptor family 8 subfamily K member 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15313]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000280411	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-69D	immunoglobulin heavy variable 1-69D [Source:HGNC Symbol;Acc:HGNC:49601]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000280433	2.279	1.671	2.5	1.748	2.087	2.321	171.8	126.61	139.16	97.58	132.89	127.27	TRAPPC10	"novel protein, similar to trafficking protein particle complex 10 TRAPPC10"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:1990071//TRAPPII protein complex	-	GO:0006891//intra-Golgi vesicle-mediated transport;GO:0034498//early endosome to Golgi transport;GO:0048193//Golgi vesicle transport	--
ENSG00000280537	0	0	0	0	0	0	0	0	0	0	0	0	SLC23A3	"novel protein, SLC23A3-NHEJ1 readthrough"	-	-	-	-	-	-	-	--
ENSG00000280571	3.277	2.781	2.194	3.398	0.91	4.691	56.66	48.25	20.23	31.43	9.6	42.62	CCDC13	novel protein	-	-	-	-	GO:0005654//nucleoplasm;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0034451//centriolar satellite	-	-	--
ENSG00000280670	0.531	0.34	0.39	0.533	0.334	0.355	22	15	13	15	12	11	CCDC163	coiled-coil domain containing 163 [Source:HGNC Symbol;Acc:HGNC:27003]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000280709	0	0	0	0	0	0	0	0	0	0	0	0	LINC02203	long intergenic non-protein coding RNA 2203 [Source:HGNC Symbol;Acc:HGNC:53069]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000280778	0	0	0	0	0	0	0	0	0	0	0	0	POLR3GL	"novel protein, lncRNA-POLR3GL readthrough"	Organismal Systems;Genetic Information Processing	Immune system;Transcription	ko04623//Cytosolic DNA-sensing pathway;ko03020//RNA polymerase	K03024;K03024	GO:0005634//nucleus;GO:0005666//RNA polymerase III complex	-	GO:0006383//transcription by RNA polymerase III	--
ENSG00000280789	5.887	5.673	7.101	6.606	6.88	6.26	473.01	458.21	421.4	393.19	467.09	365.98	PAGR1	PAXIP1 associated glutamate rich protein 1 [Source:HGNC Symbol;Acc:HGNC:28707]	-	-	-	-	GO:0005634//nucleus;GO:0035097//histone methyltransferase complex;GO:0044666//MLL3/4 complex	GO:0005515//protein binding;GO:0030331//estrogen receptor binding	GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0045944//positive regulation of transcription by RNA polymerase II;GO:0051568//histone H3-K4 methylation;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000280893	3.366	3.782	3.959	4.979	3.261	5.518	157.23	177.58	136.59	172.28	128.7	187.54	PRRT2	novel transcript	-	-	-	-	GO:0016021//integral component of membrane	-	-	--
ENSG00000280969	0	0	0	0	0	0	0	0	0	0	0	0	RPS4Y2	ribosomal protein S4 Y-linked 2 [Source:HGNC Symbol;Acc:HGNC:18501]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02987;K02987	GO:0005575//cellular_component;GO:0005840//ribosome;GO:0022627//cytosolic small ribosomal subunit	GO:0003674//molecular_function;GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding	GO:0006412//translation;GO:0008150//biological_process	--
ENSG00000280987	6.71	8.28	8.762	3.433	8.589	4.847	586.55	676.4	533.68	206.92	508.86	270.02	MATR3	matrin 3 [Source:NCBI gene (formerly Entrezgene);Acc:9782]	Human Diseases	Neurodegenerative disease	ko05014//Amyotrophic lateral sclerosis	K13213	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding	-	--
ENSG00000281039	0	0.103	0	0	0	0	0	1.47	0	0	0	0	GGCT	novel protein	Metabolism;Metabolism	Global and overview maps;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00480//Glutathione metabolism	K00682;K00682	-	GO:0003839//gamma-glutamylcyclotransferase activity;GO:0016829//lyase activity	-	--
ENSG00000281106	0	0.012	0	0.032	0	0.033	0	1	0	2	0	2	TMEM272	transmembrane protein 272 [Source:HGNC Symbol;Acc:HGNC:26737]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000281179	0	0	0	0	0	0	0	0	0	0	0	0	IGHV1-2	novel gene identicle to IGHV1OR15-1	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0009897//external side of plasma membrane;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000281348	0	0	0	0.314	0	0.237	0	0	0	2.68	0	1.99	PAGR1	novel protein	-	-	-	-	GO:0044666//MLL3/4 complex	GO:0030331//estrogen receptor binding	GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0051568//histone H3-K4 methylation;GO:1902808//positive regulation of cell cycle G1/S phase transition	--
ENSG00000281406	1.224	0.488	0.657	0.403	0.557	0.667	113	63	65	40	63	62	BLACAT1	bladder cancer associated transcript 1 [Source:HGNC Symbol;Acc:HGNC:48597]	-	-	-	-	-	-	-	--
ENSG00000281593	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein, ZNRF2-LINC01176 readthrough"	-	-	-	-	-	-	-	--
ENSG00000281613	0	0	0	0.073	0.064	0	0	0	0	1	1	0	RFPL4B	novel ret finger protein-like 4B	-	-	-	-	-	GO:0046872//metal ion binding	-	--
ENSG00000281883	0.054	0	0	0	0	0	2	0	0	0	0	0	LACC1	novel transcript	Metabolism;Metabolism	Nucleotide metabolism;Amino acid metabolism	ko00230//Purine metabolism;ko00270//Cysteine and methionine metabolism	K05810;K05810	-	GO:0004000//adenosine deaminase activity;GO:0004731//purine-nucleoside phosphorylase activity;GO:0005507//copper ion binding;GO:0016740//transferase activity;GO:0017061//S-methyl-5-thioadenosine phosphorylase activity;GO:0046872//metal ion binding	-	--
ENSG00000281887	0	0	0	0	0	0	0	0	0	0	0	0	GIMAP1-GIMAP5	GIMAP1-GIMAP5 readthrough [Source:HGNC Symbol;Acc:HGNC:51257]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005525//GTP binding	-	--
ENSG00000281938	0	0	0	0	0	0	0	0	0	0	0	0	ACSL6	novel transcript	Metabolism;Organismal Systems;Cellular Processes;Organismal Systems;Organismal Systems;Metabolism;Metabolism;Cellular Processes;Metabolism	Global and overview maps;Environmental adaptation;Transport and catabolism;Endocrine system;Endocrine system;Global and overview maps;Lipid metabolism;Cell growth and death;Lipid metabolism	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko04146//Peroxisome;ko03320//PPAR signaling pathway;ko04920//Adipocytokine signaling pathway;ko01212//Fatty acid metabolism;ko00071//Fatty acid degradation;ko04216//Ferroptosis;ko00061//Fatty acid biosynthesis	K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897;K01897	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004467//long-chain fatty acid-CoA ligase activity	GO:0001676//long-chain fatty acid metabolic process;GO:0006631//fatty acid metabolic process	--
ENSG00000281958	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-4	T cell receptor beta joining 1-4 [Source:HGNC Symbol;Acc:HGNC:12165]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000281990	0	0	0	0	0.162	0	0	0	0	0	1	0	IGHV1-69-2	immunoglobulin heavy variable 1-69-2 [Source:HGNC Symbol;Acc:HGNC:5562]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000281991	0	0	0	0	0	0	0	0	0	0	0	0	TMEM265	transmembrane protein 265 [Source:HGNC Symbol;Acc:HGNC:51241]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000282034	1.778	2.334	2.201	3.171	2.387	3.68	431.19	568.98	394.18	569.68	489.15	649.33	SRCAP	novel transcript	-	-	-	-	GO:0000812//Swr1 complex;GO:0005634//nucleus	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0042393//histone binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0043486//histone exchange	--
ENSG00000282089	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000282122	0	0	0	0	0	0	0	0	0	0	0	0	IGHV7-4-1	immunoglobulin heavy variable 7-4-1 [Source:HGNC Symbol;Acc:HGNC:5665]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000282133	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-3	T cell receptor beta joining 1-3 [Source:HGNC Symbol;Acc:HGNC:12164]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282173	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-5	T cell receptor beta joining 1-5 [Source:HGNC Symbol;Acc:HGNC:12166]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282218	0	0	0	0	0	0	0	0	0	0	0	0	GOPC	"novel protein, GOPC-ROS1 readthrough"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0043229//intracellular organelle	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0044325//transmembrane transporter binding;GO:0046872//metal ion binding	GO:0006468//protein phosphorylation;GO:0043004//cytoplasmic sequestering of CFTR protein;GO:2000009//negative regulation of protein localization to cell surface	--
ENSG00000282246	0.527	0.194	0.364	0.483	0.398	0.204	13.15	4.86	6.71	7.55	8.4	3.71	PRPF18	novel protein	Genetic Information Processing	Transcription	ko03040//Spliceosome	K12817	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071021//U2-type post-spliceosomal complex	-	GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0071028//nuclear mRNA surveillance	--
ENSG00000282268	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000282278	0.089	0	0.053	0	0	0.434	4.69	0	2.07	0	0	16.72	PDGFRA	novel FIP1L1-PDGFRA fusion protein	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Transport and catabolism;Signal transduction;Infectious disease: viral;Cell motility;Signal transduction;Signal transduction;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Cancer: overview;Cancer: specific types;Cellular community - eukaryotes;Drug resistance: antineoplastic;Cancer: specific types;Cancer: specific types;Cancer: overview	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko04010//MAPK signaling pathway;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko05163//Human cytomegalovirus infection;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04630//JAK-STAT signaling pathway;ko05231//Choline metabolism in cancer;ko05215//Prostate cancer;ko04540//Gap junction;ko01521//EGFR tyrosine kinase inhibitor resistance;ko05214//Glioma;ko05218//Melanoma;ko05230//Central carbon metabolism in cancer	K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363;K04363	GO:0005634//nucleus;GO:0005654//nucleoplasm	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding	GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042127//regulation of cell population proliferation;GO:0042327//positive regulation of phosphorylation;GO:0046777//protein autophosphorylation;GO:0048584//positive regulation of response to stimulus	--
ENSG00000282301	0	0	0	0	0	0	0	0	0	0	0	0	CYP3A7-CYP3A51P	CYP3A7-CYP3A51P readthrough [Source:HGNC Symbol;Acc:HGNC:51504]	Metabolism;Human Diseases;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Metabolism of cofactors and vitamins;Lipid metabolism	ko01100//Metabolic pathways;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00140//Steroid hormone biosynthesis	K17691;K17691;K17691;K17691	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0046872//metal ion binding;GO:0070330//aromatase activity"	-	--
ENSG00000282320	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-1	T cell receptor beta joining 1-1 [Source:HGNC Symbol;Acc:HGNC:12162]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282419	0	0	0	0	0	0	0	0	0	0	0	0	TEX13D	TEX13 family member D [Source:HGNC Symbol;Acc:HGNC:52278]	-	-	-	-	GO:0005737//cytoplasm	GO:0003729//mRNA binding;GO:0046872//metal ion binding	-	--
ENSG00000282420	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-2	T cell receptor beta joining 1-2 [Source:HGNC Symbol;Acc:HGNC:12163]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282431	0	0	0	0	0	0	0	0	0	0	0	0	TRBD1	T cell receptor beta diversity 1 [Source:HGNC Symbol;Acc:HGNC:12158]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282520	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000282599	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000282608	0	0	0	0	0.065	0	0	0	0	0	2	0	ADORA3	adenosine A3 receptor [Source:HGNC Symbol;Acc:HGNC:268]	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing	Signaling molecules and interaction;Signal transduction;Signal transduction	ko04080//Neuroactive ligand-receptor interaction;ko04022//cGMP-PKG signaling pathway;ko04071//Sphingolipid signaling pathway	K04268;K04268;K04268	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0042734//presynaptic membrane	GO:0001609//G protein-coupled adenosine receptor activity;GO:0004930//G protein-coupled receptor activity	GO:0001973//G protein-coupled adenosine receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0008285//negative regulation of cell population proliferation;GO:0009611//response to wounding;GO:0014061//regulation of norepinephrine secretion;GO:0030336//negative regulation of cell migration;GO:0032088//negative regulation of NF-kappaB transcription factor activity	--
ENSG00000282639	0	0	0	0	0	0	0	0	0	0	0	0	IGHV3-64D	immunoglobulin heavy variable 3-64D [Source:HGNC Symbol;Acc:HGNC:49603]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000282651	0	0	0	0	0	0	0	0	0	0	0	0	IGHV5-10-1	immunoglobulin heavy variable 5-10-1 [Source:HGNC Symbol;Acc:HGNC:5661]	Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Environmental Information Processing;Cellular Processes;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Signal transduction;Transport and catabolism;Immune disease;Infectious disease: bacterial;Immune system;Signal transduction;Infectious disease: parasitic;Immune system;Infectious disease: bacterial;Immune system;Cardiovascular disease;Immune disease;Immune system;Infectious disease: parasitic;Immune system;Cardiovascular disease;Immune disease;Immune disease;Immune system;Immune disease;Infectious disease: parasitic;Immune disease	ko04151//PI3K-Akt signaling pathway;ko04020//Calcium signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05152//Tuberculosis;ko04072//Phospholipase D signaling pathway;ko04145//Phagosome;ko05322//Systemic lupus erythematosus;ko05135//Yersinia infection;ko04650//Natural killer cell mediated cytotoxicity;ko04064//NF-kappa B signaling pathway;ko05146//Amoebiasis;ko04666//Fc gamma R-mediated phagocytosis;ko05150//Staphylococcus aureus infection;ko04640//Hematopoietic cell lineage;ko05414//Dilated cardiomyopathy;ko05323//Rheumatoid arthritis;ko04662//B cell receptor signaling pathway;ko05140//Leishmaniasis;ko04664//Fc epsilon RI signaling pathway;ko05416//Viral myocarditis;ko05320//Autoimmune thyroid disease;ko05340//Primary immunodeficiency;ko04672//Intestinal immune network for IgA production;ko05330//Allograft rejection;ko05143//African trypanosomiasis;ko05310//Asthma	K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856;K06856	"GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0019814//immunoglobulin complex;GO:0042571//immunoglobulin complex, circulating"	GO:0003823//antigen binding;GO:0034987//immunoglobulin receptor binding	"GO:0002250//adaptive immune response;GO:0002376//immune system process;GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0006958//complement activation, classical pathway;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0050853//B cell receptor signaling pathway;GO:0050871//positive regulation of B cell activation"	--
ENSG00000282757	0	0	0	0	0	0	0	0	0	0	0	0	DUXB	double homeobox B [Source:HGNC Symbol;Acc:HGNC:33345]	-	-	-	-	GO:0005634//nucleus	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	Homeobox
ENSG00000282780	0	0	0	0	0	0	0	0	0	0	0	0	TRBJ1-6	T cell receptor beta joining 1-6 [Source:HGNC Symbol;Acc:HGNC:12167]	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0042101//T cell receptor complex	-	GO:0002250//adaptive immune response;GO:0002376//immune system process	--
ENSG00000282804	0	0	0	0	0	0	0	0	0	0	0	0	RIPOR2	novel protein	-	-	-	-	-	-	GO:0007605//sensory perception of sound;GO:0048741//skeletal muscle fiber development	--
ENSG00000282815	0	0	0	0	0	0	0	0	0	0	0	0	TEX13C	TEX13 family member C [Source:HGNC Symbol;Acc:HGNC:52277]	-	-	-	-	GO:0005737//cytoplasm	GO:0003729//mRNA binding;GO:0046872//metal ion binding	-	--
ENSG00000282872	0	0.088	0	0	0	0	0	2	0	0	0	0	C1orf232	chromosome 1 open reading frame 230 [Source:HGNC Symbol;Acc:HGNC:53426]	-	-	-	-	-	-	-	--
ENSG00000282881	0	0	0.08	0	0	0	0	0	2	0	0	0	TMEM275	transmembrane protein 275 [Source:HGNC Symbol;Acc:HGNC:53938]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000282936	0.12	0.089	0.135	0.19	0.178	0.167	12.03	9.02	10	14.13	15.1	12.2	--	novel protein	Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Environmental Information Processing	Signal transduction;Infectious disease: viral;Cardiovascular disease;Cancer: overview;Cellular community - eukaryotes;Infectious disease: parasitic;Endocrine system;Immune system;Digestive system;Endocrine and metabolic disease;Signaling molecules and interaction	ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05415//Diabetic cardiomyopathy;ko05205//Proteoglycans in cancer;ko04510//Focal adhesion;ko05146//Amoebiasis;ko04926//Relaxin signaling pathway;ko04611//Platelet activation;ko04974//Protein digestion and absorption;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04512//ECM-receptor interaction	K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236;K06236	-	-	-	--
ENSG00000282988	0.131	0.118	0.335	0.049	0	0.101	4.29	4	6	1.22	0	2.45	H2AC7	novel protein	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	-	--
ENSG00000283039	0	0	0	0	0	0	0	0	0	0	0	0	KLF18	Kruppel like factor 18 [Source:HGNC Symbol;Acc:HGNC:51793]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000283071	0	0	0	0	0	0	0	0	0	0	0	0	LBHD2	LBH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:52384]	-	-	-	-	-	-	-	--
ENSG00000283093	0.401	0.216	0.264	0.284	0.516	0.591	13.47	7.31	6.54	7.06	14.65	14.44	CENPVL2	centromere protein V like 2 [Source:HGNC Symbol;Acc:HGNC:43879]	-	-	-	-	-	GO:0016846//carbon-sulfur lyase activity;GO:0046872//metal ion binding	-	--
ENSG00000283128	0.041	0.014	0.037	0	0.032	0.051	3	1	2	0	2	2.7	CNPY1	novel transcript	-	-	-	-	-	-	-	--
ENSG00000283149	4.763	0	2.549	7.231	0.97	0.913	49.5	0	19.56	55.66	8.52	6.9	DNAJB11	novel protein	Genetic Information Processing	"Folding, sorting and degradation"	ko04141//Protein processing in endoplasmic reticulum	K09517	GO:0005783//endoplasmic reticulum	GO:0051082//unfolded protein binding	GO:0006457//protein folding	--
ENSG00000283154	3.054	5.058	3.809	6.324	4.004	4.853	104.36	138.46	116.23	115.51	86.54	94.88	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough [Source:HGNC Symbol;Acc:HGNC:38842]	-	-	-	-	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0042995//cell projection;GO:0043194//axon initial segment	GO:0005515//protein binding	GO:0035332//positive regulation of hippo signaling;GO:0051494//negative regulation of cytoskeleton organization	--
ENSG00000283189	0.181	0.133	0.657	0.354	0	0.312	19.08	14.02	47.33	27.51	0	23.9	AMT	novel protein	Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism;Metabolism of cofactors and vitamins	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism;ko00670//One carbon pool by folate"	K00605;K00605;K00605;K00605;K00605	GO:0005654//nucleoplasm;GO:0005739//mitochondrion	GO:0004047//aminomethyltransferase activity;GO:0005515//protein binding;GO:0008483//transaminase activity;GO:0016740//transferase activity	GO:0006546//glycine catabolic process	--
ENSG00000283199	0.115	0.089	0.034	0.034	0.015	0.018	9	7	2	2	1	1	C13orf46	chromosome 13 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:53786]	-	-	-	-	-	-	-	--
ENSG00000283201	0.765	0.247	0.28	0.16	0.165	0.375	30.2	9.79	8.18	4.67	5.51	10.77	ZNF724	zinc finger protein 724 [Source:NCBI gene (formerly Entrezgene);Acc:440519]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	"GO:0000977//RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227//DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0046872//metal ion binding"	"GO:0000122//negative regulation of transcription by RNA polymerase II;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	zf-C2H2
ENSG00000283205	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000283208	0.261	0.156	0	0	0.262	0.15	10.65	6.07	0	0	11.16	4.21	CLN5	novel protein	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K12390	GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016798//hydrolase activity, acting on glycosyl bonds"	GO:0007040//lysosome organization	--
ENSG00000283227	0	0	0	0	0	0	0	0	0	0	0	0	SPRR5	small proline rich protein 5 [Source:HGNC Symbol;Acc:HGNC:53428]	-	-	-	-	-	-	-	--
ENSG00000283228	3.241	5.286	4.214	2.029	0.103	2.269	87.6	143.6	84.11	40.62	2.35	44.61	CACNB4	novel transcript	Environmental Information Processing;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Cardiovascular disease;Endocrine system;Circulatory system;Cardiovascular disease;Circulatory system;Cardiovascular disease	ko04010//MAPK signaling pathway;ko05414//Dilated cardiomyopathy;ko04921//Oxytocin signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko05410//Hypertrophic cardiomyopathy;ko04260//Cardiac muscle contraction;ko05412//Arrhythmogenic right ventricular cardiomyopathy	K04865;K04865;K04865;K04865;K04865;K04865;K04865	GO:0005891//voltage-gated calcium channel complex	GO:0005245//voltage-gated calcium channel activity	GO:0070588//calcium ion transmembrane transport	--
ENSG00000283239	0.286	0.252	0.089	0.141	0.129	0.05	23.68	10.7	2.79	4.43	4.61	1.54	CLN8	novel transcript	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283247	0	0	0	0	0	0	0	0	0	0	0	0	CCDC201	coiled-coil domain containing 201 [Source:HGNC Symbol;Acc:HGNC:54081]	-	-	-	-	-	-	-	--
ENSG00000283267	0.012	0	0	0	0.051	0	1	0	0	0	3	0	FAM237B	family with sequence similarity 237 member B [Source:HGNC Symbol;Acc:HGNC:53217]	-	-	-	-	-	-	-	--
ENSG00000283268	0	0	0	0.671	0	0	0	0	0	5	0	0	TEX54	testis expressed 54 [Source:HGNC Symbol;Acc:HGNC:53729]	-	-	-	-	-	-	-	--
ENSG00000283288	0	0	0	0	0	0	0	0	0	0	0	0	SMIM33	small integral membrane protein 33 [Source:HGNC Symbol;Acc:HGNC:53645]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283297	0.043	0.043	0	0.175	0	0	1	1	0	3	0	0	TEX52	testis expressed 52 [Source:HGNC Symbol;Acc:HGNC:53643]	-	-	-	-	-	-	-	--
ENSG00000283321	0	0.06	0	0	0	0	0	4.42	0	0	0	0	AHR	novel protein	Human Diseases;Human Diseases;Human Diseases;Organismal Systems	Cancer: overview;Cancer: overview;Endocrine and metabolic disease;Immune system	ko05208//Chemical carcinogenesis - reactive oxygen species;ko05207//Chemical carcinogenesis - receptor activation;ko04934//Cushing syndrome;ko04659//Th17 cell differentiation	K09093;K09093;K09093;K09093	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0034751//aryl hydrocarbon receptor complex	GO:0000976//transcription cis-regulatory region binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0004879//nuclear receptor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II;GO:0006805//xenobiotic metabolic process;GO:0009410//response to xenobiotic stimulus;GO:0030522//intracellular receptor signaling pathway;GO:0048511//rhythmic process"	bHLH
ENSG00000283324	0	0.039	0	0	0	0	0	1	0	0	0	0	CTXND2	cortexin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:53440]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283329	0	0	0	0	0	0	0	0	0	0	0	0	FAM240B	family with sequence similarity 240 member B [Source:HGNC Symbol;Acc:HGNC:53430]	-	-	-	-	-	-	-	--
ENSG00000283361	0	0	0	0	0	0	0	0	0	0	0	0	CFAP97D2	CFAP97 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:53789]	-	-	-	-	-	-	-	--
ENSG00000283378	3.525	3.345	3.723	2.223	3.012	4.58	126.34	120.52	98.56	59.01	91.2	119.43	CNTNAP3C	contactin associated protein family member 3C [Source:HGNC Symbol;Acc:HGNC:53878]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283428	0	0	0	0	0	0	0	0	0	0	0	0	CCDC195	coiled-coil domain containing 195 [Source:HGNC Symbol;Acc:HGNC:53441]	-	-	-	-	-	-	-	--
ENSG00000283434	0	0	0	0	0	0	0	0	0	0	0	0	CSNKA2IP	casein kinase 2 subunit alpha' interacting protein [Source:HGNC Symbol;Acc:HGNC:53637]	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000283439	0	0	0	0	0	0	0	0	0	0	0	0	SPEM3	SPEM family member 3 [Source:HGNC Symbol;Acc:HGNC:53651]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283463	0	0	0	0	0	0	0	0	0	0	0	0	HSFX4	"heat shock transcription factor family, X-linked member 4 [Source:HGNC Symbol;Acc:HGNC:52398]"	-	-	-	-	GO:0005634//nucleus	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000283473	0	0	0	0	0	0	0	0	0	0	0	0	FAM240A	family with sequence similarity 240 member A [Source:HGNC Symbol;Acc:HGNC:52390]	-	-	-	-	-	-	-	--
ENSG00000283486	0.49	0.271	0.371	0.498	1.002	0.11	19	8.4	11.5	14	29.36	2	FAM95C	family with sequence similarity 95 member C [Source:HGNC Symbol;Acc:HGNC:45272]	-	-	-	-	-	-	-	--
ENSG00000283496	0	0	0	0	0	0	0	0	0	0	0	0	ZNF511-PRAP1	ZNF511-PRAP1 readthrough [Source:HGNC Symbol;Acc:HGNC:38088]	-	-	-	-	-	-	-	--
ENSG00000283515	0.832	1.072	1.393	1.655	0.909	1.476	52.49	67.96	62.45	77.37	48.47	67.78	ZNF544	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000283516	0	0	0	0	0	0	0	0	0	0	0	0	LITAFD	LITAF domain containing [Source:HGNC Symbol;Acc:HGNC:53927]	Cellular Processes	Transport and catabolism	ko04142//Lysosome	K19363	GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0098560//cytoplasmic side of late endosome membrane;GO:0098574//cytoplasmic side of lysosomal membrane	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0001817//regulation of cytokine production	zf-LITAF-like
ENSG00000283526	0	0	0	0	0	0	0	0	0	0	0	0	PRRT1B	proline rich transmembrane protein 1B [Source:HGNC Symbol;Acc:HGNC:53642]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000283528	0	0.198	0	0.143	0.034	0.051	0	10.64	0	5.67	1.53	1.97	TCAF2C	TRPM8 channel associated factor 2C [Source:HGNC Symbol;Acc:HGNC:53641]	-	-	-	-	GO:0005886//plasma membrane;GO:0030054//cell junction	GO:0044325//transmembrane transporter binding	GO:0010359//regulation of anion channel activity;GO:0010360//negative regulation of anion channel activity;GO:0090314//positive regulation of protein targeting to membrane	--
ENSG00000283536	0.115	0.287	0.078	0.156	0.547	0.397	2	5	1	2	8	5	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000283563	0.177	0	0.021	0	0.02	0.023	12.96	0	1.16	0	1.22	1.21	ZCWPW2	novel protein	-	-	-	-	-	GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000283567	0.036	0	0	0.049	0	0	1	0	0	1	0	0	C19orf85	chromosome 19 open reading frame 85 [Source:HGNC Symbol;Acc:HGNC:53653]	-	-	-	-	-	-	-	--
ENSG00000283580	0.107	1.305	1.242	0	0.192	1.11	2.23	27.42	19.18	0	3.39	16.88	C1orf50	novel protein	-	-	-	-	-	-	-	--
ENSG00000283586	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000283594	0	0	0	0	0	0	0	0	0	0	0	0	FAM236C	family with sequence similarity 236 member C [Source:HGNC Symbol;Acc:HGNC:52641]	-	-	-	-	-	-	-	--
ENSG00000283599	0	0	0	0	0	0	0	0	0	0	0	0	CXorf49	novel protein similar to CXorf49	-	-	-	-	-	-	-	--
ENSG00000283632	0.06	0	0.02	0	0.036	0	4	0	1	0	2	0	EXOC3L2	exocyst complex component 3 like 2 [Source:HGNC Symbol;Acc:HGNC:30162]	-	-	-	-	GO:0000145//exocyst	-	GO:0001701//in utero embryonic development;GO:0006887//exocytosis	--
ENSG00000283644	0	0	0	0	0	0	0	0	0	0	0	0	ETDC	embryonic testis differentiation homolog C [Source:HGNC Symbol;Acc:HGNC:53450]	-	-	-	-	-	-	-	--
ENSG00000283654	0	0	0	0	0	0	0	0	0	0	0	0	LMLN2	leishmanolysin like peptidase 2 [Source:HGNC Symbol;Acc:HGNC:53647]	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007155//cell adhesion	--
ENSG00000283663	0	0	0	0	0	0	0	0	0	0	0	0	NTF4	novel transcript	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signal transduction;Signal transduction;Nervous system	ko04151//PI3K-Akt signaling pathway;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04722//Neurotrophin signaling pathway	K12457;K12457;K12457;K12457	GO:0005576//extracellular region	GO:0008083//growth factor activity	GO:0007165//signal transduction	--
ENSG00000283683	0	0	0	0	0	0	0	0	0	0	0	0	MYOCOS	myocilin opposite strand [Source:HGNC Symbol;Acc:HGNC:53429]	-	-	-	-	-	-	-	--
ENSG00000283697	0	0	0	0	0	0	0	0	0	0	0	0	HSFX3	"heat shock transcription factor family, X-linked member 3 [Source:HGNC Symbol;Acc:HGNC:52395]"	-	-	-	-	GO:0000785//chromatin;GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0043565//sequence-specific DNA binding"	"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription by RNA polymerase II"	HSF
ENSG00000283703	0	0	0	0	0	0	0	0	0	0	0	0	VSIG10L2	V-set and immunoglobulin domain containing 10 like 2 [Source:HGNC Symbol;Acc:HGNC:27879]	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding	GO:0098609//cell-cell adhesion	--
ENSG00000283706	0	0	0	0.202	0	0.05	0	0	0	4.14	0	1	PRSS50	serine protease 50 [Source:HGNC Symbol;Acc:HGNC:17910]	-	-	-	-	GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum	GO:0004252//serine-type endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0016787//hydrolase activity	GO:0006508//proteolysis	--
ENSG00000283740	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L11	TATA-box binding protein associated factor 11 like 11 [Source:HGNC Symbol;Acc:HGNC:53854]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000283755	0	0	0	0	0	0	0	0	0	0	0	0	CPHXL	cytoplasmic polyadenylated homeobox like [Source:HGNC Symbol;Acc:HGNC:51815]	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	Homeobox
ENSG00000283758	0	0	0	0	0	0	0	0	0	0	0	0	PMIS2	PMIS2 transmembrane protein [Source:HGNC Symbol;Acc:HGNC:53649]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle	-	-	--
ENSG00000283761	2.663	2.578	0.939	0.972	2.424	1.746	146.7	142.17	43.41	43.04	107.8	72.04	MFSD14A	novel protein	-	-	-	-	GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0022857//transmembrane transporter activity	GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport	--
ENSG00000283765	0	0	0.538	0	0.187	0	0	0	25.18	0	10	0	PARL	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004252//serine-type endopeptidase activity	GO:0006508//proteolysis	--
ENSG00000283776	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L13	TATA-box binding protein associated factor 11 like 13 [Source:HGNC Symbol;Acc:HGNC:53856]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000283782	0.769	0.72	1.082	0.717	0.868	1.364	126.17	118.54	130.78	86.93	120.04	162.48	RAD50	novel protein	Cellular Processes;Genetic Information Processing;Genetic Information Processing	Cell growth and death;Replication and repair;Replication and repair	ko04218//Cellular senescence;ko03440//Homologous recombination;ko03450//Non-homologous end-joining	K10866;K10866;K10866	GO:0005634//nucleus;GO:0030870//Mre11 complex	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0006996//organelle organization	--
ENSG00000283787	0.013	0	0	0	0	0	1	0	0	0	0	0	PRR33	proline rich 33 [Source:HGNC Symbol;Acc:HGNC:35118]	-	-	-	-	-	-	-	--
ENSG00000283809	1.886	1.788	2.134	2.796	1.537	2.039	65.28	62.22	54.57	71.71	44.94	51.35	DGCR6	novel protein	-	-	-	-	-	-	-	--
ENSG00000283873	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P4	SSU72 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:43623]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000283877	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000283886	3.648	3.48	3.63	4.447	4.473	4.141	142.86	137	105	129	148	118	--	Q8NFD4.1 RecName: Full=Uncharacterized protein FLJ76381 [Homo sapiens]	-	-	-	-	-	-	-	--
ENSG00000283900	1.206	0.532	0.593	1.343	1.259	1.789	44.28	19.62	16.07	36.52	39.05	47.8	TPTEP2-CSNK1E	TPTEP2-CSNK1E readthrough [Source:HGNC Symbol;Acc:HGNC:53829]	Human Diseases;Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Neurodegenerative disease;Neurodegenerative disease;Signal transduction;Signal transduction;Signal transduction;Signal transduction;Environmental adaptation;Signal transduction;Signal transduction;Signal transduction;Environmental adaptation	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04310//Wnt signaling pathway;ko04390//Hippo signaling pathway;ko04068//FoxO signaling pathway;ko04340//Hedgehog signaling pathway;ko04710//Circadian rhythm;ko04392//Hippo signaling pathway - multiple species;ko04391//Hippo signaling pathway - fly;ko04341//Hedgehog signaling pathway - fly;ko04711//Circadian rhythm - fly	K08960;K08960;K08960;K08960;K08960;K08960;K08960;K08960;K08960;K08960;K08960	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000283930	0	0	0	0	0	0	0	0	0	0	0	0	PLD5P1	PLD5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:55072]	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000283952	0	0	0	0	0	0	0	0	0	0	0	0	KCNH1	novel protein	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane	GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005516//calmodulin binding	GO:0006813//potassium ion transport;GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport	--
ENSG00000283967	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L8	TATA-box binding protein associated factor 11 like 8 [Source:HGNC Symbol;Acc:HGNC:53851]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000283977	0	0	0	0	0	0	0	0	0	0	0	0	TIMM10B	novel transcript	-	-	-	-	GO:0005740//mitochondrial envelope	-	GO:0006626//protein targeting to mitochondrion	--
ENSG00000283980	0	0	0	0	0	0	0	0	0	0	0	0	GNG14	G protein subunit gamma 14 [Source:HGNC Symbol;Acc:HGNC:53439]	-	-	-	-	GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0016020//membrane	GO:0031681//G-protein beta-subunit binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway	--
ENSG00000283988	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L9	TATA-box binding protein associated factor 11 like 9 [Source:HGNC Symbol;Acc:HGNC:53852]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000283992	0.227	0.247	0.112	0.112	0.129	0.333	2.74	3	1	1	1.32	2.93	SLURP2	secreted LY6/PLAUR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25549]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23682	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0045202//synapse	GO:0030548//acetylcholine receptor regulator activity;GO:0030550//acetylcholine receptor inhibitor activity;GO:0033130//acetylcholine receptor binding	GO:0095500//acetylcholine receptor signaling pathway;GO:0099601//regulation of neurotransmitter receptor activity;GO:2000272//negative regulation of signaling receptor activity	--
ENSG00000284018	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P5	SSU72 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:43624]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000284024	4.005	3.974	4.676	3.35	3.615	3.959	387.09	386.06	314.52	239.87	295.22	278.44	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000284042	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L6	TATA-box binding protein associated factor 11 like 6 [Source:HGNC Symbol;Acc:HGNC:53849]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284057	0.891	0.652	1.104	0.616	0	0.372	55.33	40.7	50.62	28.34	0	16.81	MED17	"novel protein, C11orf54-MED17 readthrough"	Organismal Systems	Endocrine system	ko04919//Thyroid hormone signaling pathway	K15133	GO:0005634//nucleus;GO:0016592//mediator complex	GO:0003712//transcription coregulator activity;GO:0046872//metal ion binding	GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000284188	0	0	0.184	0	0	0	0	0	3	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000284194	3.215	2.934	4.415	5.705	4.907	4.547	66.38	59.26	66.55	86.25	85.19	67.52	SCO2	synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604]	Human Diseases	Cancer: overview	ko05230//Central carbon metabolism in cancer	K23755	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030016//myofibril;GO:0031305//integral component of mitochondrial inner membrane	GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0015035//protein-disulfide reductase activity;GO:0016531//copper chaperone activity;GO:0046872//metal ion binding	GO:0001654//eye development;GO:0001701//in utero embryonic development;GO:0003012//muscle system process;GO:0006878//cellular copper ion homeostasis;GO:0008535//respiratory chain complex IV assembly;GO:0014823//response to activity;GO:0022904//respiratory electron transport chain;GO:0033617//mitochondrial cytochrome c oxidase assembly;GO:0055070//copper ion homeostasis	--
ENSG00000284234	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L5	TATA-box binding protein associated factor 11 like 5 [Source:HGNC Symbol;Acc:HGNC:53848]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284283	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L4	TATA-box binding protein associated factor 11 like 4 [Source:HGNC Symbol;Acc:HGNC:53847]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284292	0.801	0.515	1.982	0	0.465	0.375	40.39	26.1	73.77	0	19.8	13.77	ARPC1A	"novel protein, ARPC1A and ARPC1B readthrough"	Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Cellular Processes;Human Diseases;Cellular Processes;Organismal Systems;Human Diseases	Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Cell motility;Infectious disease: bacterial;Cellular community - eukaryotes;Immune system;Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04810//Regulation of actin cytoskeleton;ko05135//Yersinia infection;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko05100//Bacterial invasion of epithelial cells	K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757;K05757	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0015629//actin cytoskeleton	GO:0003779//actin binding;GO:0005515//protein binding	GO:0030833//regulation of actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation	--
ENSG00000284299	0	0	0	0	0	0	0	0	0	0	0	0	Kcnh1	novel protein	-	-	-	-	GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005516//calmodulin binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000284306	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P2	SSU72 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:43621]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000284308	2.717	2.835	3.988	2.741	2.966	3.307	125.71	116.94	101	92	100.63	87	C2orf81	chromosome 2 open reading frame 81 [Source:HGNC Symbol;Acc:HGNC:34350]	-	-	-	-	GO:0005634//nucleus	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000284337	0	0.027	0	0	0.059	0.088	0	1.79	0	0	3.3	4.26	LIMS1	novel transcript	-	-	-	-	-	-	-	--
ENSG00000284341	0.438	0.432	0.444	0	0	0.603	8.98	8.9	6.73	0	0	9	PTGDS	novel transcript	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00590//Arachidonic acid metabolism	K01830;K01830	GO:0005576//extracellular region;GO:0005791//rough endoplasmic reticulum;GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm	GO:0004667//prostaglandin-D synthase activity;GO:0016853//isomerase activity;GO:0036094//small molecule binding	GO:0001516//prostaglandin biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0043303//mast cell degranulation	--
ENSG00000284356	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L10	TATA-box binding protein associated factor 11 like 10 [Source:HGNC Symbol;Acc:HGNC:53853]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284373	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L2	TATA-box binding protein associated factor 11 like 2 [Source:HGNC Symbol;Acc:HGNC:53845]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284393	0	0	0	0	0	0	0	0	0	0	0	0	CLEC4A	novel protein	-	-	-	-	-	-	-	--
ENSG00000284395	0.05	0	0	0	0	0.034	2	0	0	0	0	1	PERCC1	proline and glutamate rich with coiled coil 1 [Source:HGNC Symbol;Acc:HGNC:52293]	-	-	-	-	-	-	GO:0035883//enteroendocrine cell differentiation;GO:0048546//digestive tract morphogenesis	--
ENSG00000284431	0.322	0.298	0.887	0.101	0.651	0.797	30.5	28.39	62.02	7.07	52.03	54.9	ADSL	novel protein	Metabolism;Metabolism;Metabolism	Global and overview maps;Nucleotide metabolism;Amino acid metabolism	"ko01100//Metabolic pathways;ko00230//Purine metabolism;ko00250//Alanine, aspartate and glutamate metabolism"	K01756;K01756;K01756	-	-	-	--
ENSG00000284438	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P7	SSU72 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:43626]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000284439	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L3	TATA-box binding protein associated factor 11 like 3 [Source:HGNC Symbol;Acc:HGNC:53846]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284461	0.215	0.071	0.189	0	0.61	0.188	18.47	6.12	12.01	0	44.21	11.74	RABGEF1	novel transcript	-	-	-	-	-	GO:0003677//DNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	GO:0016192//vesicle-mediated transport;GO:0050790//regulation of catalytic activity	--
ENSG00000284465	0	0	0	0	0	0	0	0	0	0	0	0	TAF11L7	TATA-box binding protein associated factor 11 like 7 [Source:HGNC Symbol;Acc:HGNC:53850]	Genetic Information Processing	Transcription	ko03022//Basal transcription factors	K03135	GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex	GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity	"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051123//RNA polymerase II preinitiation complex assembly"	--
ENSG00000284479	0	0	0	0	0	0	0	0	0	0	0	0	SMIM39	small integral membrane protein 39 [Source:HGNC Symbol;Acc:HGNC:54076]	Cellular Processes	Cell motility	ko04810//Regulation of actin cytoskeleton	K05769	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284484	0	0	0	0	0	0	0	0	0	0	0	0	CPHXL	novel protein similar to cytoplasmic polyadenylated homeobox like CPHXL	-	-	-	-	GO:0005634//nucleus	"GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981//DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677//DNA binding"	GO:0006357//regulation of transcription by RNA polymerase II	Homeobox
ENSG00000284491	0.085	0	0.104	0	0	0	2.21	0	2	0	0	0	THSD8	thrombospondin type 1 domain containing 8 [Source:HGNC Symbol;Acc:HGNC:53785]	-	-	-	-	-	-	-	--
ENSG00000284505	0.571	0.639	0.866	0.611	0.584	0.975	15.31	17.22	17.15	12.13	13.23	19.03	LYNX1-SLURP2	LYNX1-SLURP2 readthrough [Source:HGNC Symbol;Acc:HGNC:52291]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K23682	-	-	-	--
ENSG00000284512	0.087	0.069	0.024	0.095	0.042	0.181	5.23	4.19	1.05	4.23	2.11	6.28	GCSH	novel protein	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Global and overview maps;Amino acid metabolism;Carbohydrate metabolism	"ko01100//Metabolic pathways;ko01200//Carbon metabolism;ko00260//Glycine, serine and threonine metabolism;ko00630//Glyoxylate and dicarboxylate metabolism"	K02437;K02437;K02437;K02437	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005960//glycine cleavage complex;GO:1990204//oxidoreductase complex	-	GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0044281//small molecule metabolic process	--
ENSG00000284526	5.226	5.903	4.758	5.754	4.501	5.835	612.93	695.83	412.14	499.86	445.99	497.89	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000284546	0	0	0	0	0	0	0	0	0	0	0	0	SSU72P3	SSU72 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:43622]	Genetic Information Processing	Translation	ko03015//mRNA surveillance pathway	K15544	GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex	GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0008420//RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006397//mRNA processing;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain	--
ENSG00000284554	0	0	0	0	0	0	0	0	0	0	0	0	APOBEC3D	novel protein	Human Diseases	Infectious disease: viral	ko05170//Human immunodeficiency virus 1 infection	K18750	-	GO:0003824//catalytic activity;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	-	--
ENSG00000284609	0	0	0	0	0	0	0	0	0	0	0	0	OR8B3	olfactory receptor family 8 subfamily B member 3 [Source:HGNC Symbol;Acc:HGNC:8472]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284622	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000284626	0.023	0	0.09	0	0.094	0	1.67	0	4.72	0	5.68	0	GDPGP1	novel protein	-	-	-	-	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0016787//hydrolase activity;GO:0080048//GDP-D-glucose phosphorylase activity	-	--
ENSG00000284629	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR1	small cysteine and glycine repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:34218]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284631	0.058	0	0	0	0	0	2	0	0	0	0	0	SCYGR4	small cysteine and glycine repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:34223]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284635	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR8	small cysteine and glycine repeat containing 8 [Source:HGNC Symbol;Acc:HGNC:34227]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284638	0	0.389	0	0	0	0	0	4	0	0	0	0	SMIM44	small integral membrane protein 44 [Source:HGNC Symbol;Acc:HGNC:55815]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284643	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR2	small cysteine and glycine repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:34220]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284662	0.051	0.026	0	0	0	0.106	1	0.5	0	0	0	1.5	OR4F16	olfactory receptor family 4 subfamily F member 16 [Source:HGNC Symbol;Acc:HGNC:15079]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284667	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR5	small cysteine and glycine repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:34224]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284680	0	0	0	0	0	0	0	0	0	0	0	0	OR8B2	olfactory receptor family 8 subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:8471]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005549//odorant binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284684	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284686	0	0	0	0	0	0	0	0	0	0	0	0	PLPP3	novel transcript	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Organismal Systems	Global and overview maps;Signal transduction;Immune system;Cancer: overview;Lipid metabolism;Lipid metabolism;Lipid metabolism;Lipid metabolism;Digestive system	ko01100//Metabolic pathways;ko04072//Phospholipase D signaling pathway;ko04666//Fc gamma R-mediated phagocytosis;ko05231//Choline metabolism in cancer;ko00564//Glycerophospholipid metabolism;ko00561//Glycerolipid metabolism;ko00565//Ether lipid metabolism;ko00600//Sphingolipid metabolism;ko04975//Fat digestion and absorption	K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080;K01080	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0042577//lipid phosphatase activity	GO:0006644//phospholipid metabolic process;GO:0016311//dephosphorylation;GO:0030111//regulation of Wnt signaling pathway	--
ENSG00000284690	0	0	0	0	0	0	0	0	0	0	0	0	CD300H	CD300H molecule (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:52292]	-	-	-	-	GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding	GO:0030593//neutrophil chemotaxis	--
ENSG00000284691	0.702	0.672	0.447	0.999	1.663	0.284	17	14	8	16	34	5	--	novel zinc finger protein	-	-	-	-	-	GO:0000978//RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003700//DNA-binding transcription factor activity	GO:0006357//regulation of transcription by RNA polymerase II	zf-C2H2
ENSG00000284695	0	0	0	0	0	0.005	0	0	0	0	0	0.05	SULT1E1	novel protein	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis	K01016;K01016	GO:0005737//cytoplasm	GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:0051923//sulfation;GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000284701	0	0	0	0	0	0	0	0	0	0	0	0	TMEM247	transmembrane protein 247 [Source:HGNC Symbol;Acc:HGNC:42967]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284704	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR3	small cysteine and glycine repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:34222]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284713	0	0.053	0	0	0	0	0	3	0	0	0	0	SMIM38	small integral membrane protein 38 [Source:HGNC Symbol;Acc:HGNC:54074]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284718	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR7	small cysteine and glycine repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:34226]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284723	0	0	0	0	0	0	0	0	0	0	0	0	OR8S1	olfactory receptor family 8 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:19628]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284725	0	0	0	0	0	0	0	0	0	0	0	0	SCYGR6	small cysteine and glycine repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:34225]	-	-	-	-	GO:0005882//intermediate filament	-	-	--
ENSG00000284730	0.048	0	0	0.065	0	0.132	1	0	0	1	0	2	TMDD1	transmembrane and death domain 1 [Source:HGNC Symbol;Acc:HGNC:53646]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000284732	0	0	0	0	0	0	0	0	0	0	0	0	OR5M9	novel olfactory receptor	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284733	0.051	0.026	0	0	0	0.106	1	0.5	0	0	0	1.5	OR4F29	olfactory receptor family 4 subfamily F member 29 [Source:HGNC Symbol;Acc:HGNC:31275]	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity;GO:0005515//protein binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000284753	4.796	2.853	3.013	3.939	3.278	5.505	97	58	45	59	56	81	EEF1AKMT4	EEF1A lysine methyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:53611]	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0016740//transferase activity	GO:0018022//peptidyl-lysine methylation;GO:0032259//methylation	--
ENSG00000284762	0.66	0.467	0.237	0	0.131	0.297	46.47	33.08	12.34	0	7.77	15.21	PDE8B	"novel protein, ZBED3-AS1-PDE8B readthrough"	Metabolism;Human Diseases;Metabolism;Human Diseases;Organismal Systems	Global and overview maps;Endocrine and metabolic disease;Nucleotide metabolism;Substance dependence;Endocrine system	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00230//Purine metabolism;ko05032//Morphine addiction;ko04927//Cortisol synthesis and secretion	K18437;K18437;K18437;K18437;K18437	-	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding"	GO:0006198//cAMP catabolic process;GO:0007165//signal transduction	--
ENSG00000284770	9.06	9.136	9.653	6.748	6.151	7.414	330.02	337.6	263.39	183.97	195.44	202.78	TBCE	tubulin folding cofactor E [Source:HGNC Symbol;Acc:HGNC:11582]	-	-	-	-	GO:0005737//cytoplasm;GO:0005840//ribosome;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0043014//alpha-tubulin binding;GO:0051087//chaperone binding	GO:0000226//microtubule cytoskeleton organization;GO:0006412//translation;GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway;GO:0007052//mitotic spindle organization	--
ENSG00000284772	0	0	0	0.019	0	0	0	0	0	0.5	0	0	CATSPER2	novel transcript	-	-	-	-	-	-	-	--
ENSG00000284773	1.25	1.077	1.032	0.926	1.299	1.089	82	71	50	45	72	52	TMEM35B	novel protein	-	-	-	-	-	-	-	--
ENSG00000284776	6.682	7.262	5.029	7.818	7.67	6.061	96.33	105.23	53.54	83.48	93.42	63.57	Dtd1	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000049//tRNA binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0003723//RNA binding;GO:0016787//hydrolase activity;GO:0051499//D-aminoacyl-tRNA deacylase activity;GO:0051500//D-tyrosyl-tRNA(Tyr) deacylase activity	GO:0006399//tRNA metabolic process;GO:0106074//aminoacyl-tRNA metabolism involved in translational fidelity	--
ENSG00000284779	0	0	0	0	0	0	0	0	0	0	0	0	INS-IGF2	novel protein	Environmental Information Processing;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Environmental Information Processing;Human Diseases;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Cellular Processes;Organismal Systems;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Signal transduction;Neurodegenerative disease;Signal transduction;Signal transduction;Cell motility;Signal transduction;Signal transduction;Cardiovascular disease;Signal transduction;Endocrine and metabolic disease;Signal transduction;Transport and catabolism;Cell growth and death;Endocrine system;Signal transduction;Signal transduction;Signal transduction;Endocrine system;Endocrine and metabolic disease;Cancer: specific types;Aging;Endocrine system;Endocrine system;Aging;Endocrine system;Endocrine system;Endocrine and metabolic disease;Endocrine and metabolic disease;Excretory system;Endocrine and metabolic disease	ko04151//PI3K-Akt signaling pathway;ko05010//Alzheimer disease;ko04010//MAPK signaling pathway;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05415//Diabetic cardiomyopathy;ko04022//cGMP-PKG signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04150//mTOR signaling pathway;ko04140//Autophagy - animal;ko04114//Oocyte meiosis;ko04910//Insulin signaling pathway;ko04068//FoxO signaling pathway;ko04152//AMPK signaling pathway;ko04066//HIF-1 signaling pathway;ko04914//Progesterone-mediated oocyte maturation;ko04931//Insulin resistance;ko05215//Prostate cancer;ko04211//Longevity regulating pathway;ko04911//Insulin secretion;ko04917//Prolactin signaling pathway;ko04213//Longevity regulating pathway - multiple species;ko04923//Regulation of lipolysis in adipocytes;ko04913//Ovarian steroidogenesis;ko04930//Type II diabetes mellitus;ko04940//Type I diabetes mellitus;ko04960//Aldosterone-regulated sodium reabsorption;ko04950//Maturity onset diabetes of the young	K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526;K04526	GO:0005576//extracellular region;GO:0005615//extracellular space	GO:0005179//hormone activity	GO:0007165//signal transduction	--
ENSG00000284791	0	0	0	0	0	0	0	0	0	0	0	0	SMIM41	small integral membrane protein 41 [Source:HGNC Symbol;Acc:HGNC:54075]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284797	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284800	0	0	0	0	0	0	0	0	0	0	0	0	TCP11X2	novel transcript	-	-	-	-	-	-	-	--
ENSG00000284820	0.137	0.062	0.039	0.342	0.118	0.142	14.91	6.8	3.17	27.56	10.89	11.24	ATG9A	novel protein	Cellular Processes;Cellular Processes;Cellular Processes	Transport and catabolism;Transport and catabolism;Transport and catabolism	ko04140//Autophagy - animal;ko04137//Mitophagy - animal;ko04136//Autophagy - other	K17907;K17907;K17907	GO:0000407//phagophore assembly site;GO:0000421//autophagosome membrane;GO:0005776//autophagosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle	-	GO:0000422//autophagy of mitochondrion;GO:0006914//autophagy;GO:0034497//protein localization to phagophore assembly site;GO:0044805//late nucleophagy	--
ENSG00000284844	0	0	0	0	0	0	0	0	0	0	0	0	TOMT	transmembrane O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:55527]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Nervous system;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04728//Dopaminergic synapse;ko00140//Steroid hormone biosynthesis;ko00350//Tyrosine metabolism	K00545;K00545;K00545;K00545	GO:0005783//endoplasmic reticulum	GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0016206//catechol O-methyltransferase activity;GO:0016740//transferase activity;GO:0102084//L-dopa O-methyltransferase activity;GO:0102938//orcinol O-methyltransferase activity	GO:0006584//catecholamine metabolic process;GO:0007605//sensory perception of sound;GO:0032259//methylation;GO:0032502//developmental process;GO:0042135//neurotransmitter catabolic process;GO:0042417//dopamine metabolic process;GO:0042424//catecholamine catabolic process	--
ENSG00000284862	0.288	0.067	0.204	0.22	0.319	0.276	23	5	12	13	20	16	CCDC39	coiled-coil domain containing 39 [Source:HGNC Symbol;Acc:HGNC:25244]	-	-	-	-	GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005930//axoneme;GO:0042995//cell projection;GO:0097729//9+2 motile cilium	-	GO:0001947//heart looping;GO:0003341//cilium movement;GO:0003351//epithelial cilium movement involved in extracellular fluid movement;GO:0003356//regulation of cilium beat frequency;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0007507//heart development;GO:0030317//flagellated sperm motility;GO:0030324//lung development;GO:0035469//determination of pancreatic left/right asymmetry;GO:0036159//inner dynein arm assembly;GO:0044458//motile cilium assembly;GO:0051649//establishment of localization in cell;GO:0060285//cilium-dependent cell motility;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0061512//protein localization to cilium;GO:0061966//establishment of left/right asymmetry;GO:0070286//axonemal dynein complex assembly;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry;GO:0090660//cerebrospinal fluid circulation	--
ENSG00000284873	0	0	0	0	0	0	0	0	0	0	0	0	OOSP1	oocyte secreted protein 1 [Source:HGNC Symbol;Acc:HGNC:49233]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000284874	1.88	2.536	2.636	2.02	2.55	2.943	134.36	184.38	134.85	109.91	155.48	150.2	SEPTIN5	novel transcript	Human Diseases;Human Diseases	Neurodegenerative disease;Neurodegenerative disease	ko05022//Pathways of neurodegeneration - multiple diseases;ko05012//Parkinson disease	K04557;K04557	GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle	GO:0000166//nucleotide binding;GO:0005525//GTP binding	GO:0017157//regulation of exocytosis	--
ENSG00000284895	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000284906	0.237	0.207	0.358	0.189	0.132	0.123	36.67	24.83	28	10.52	17.28	13.8	ARHGAP11B	novel protein	-	-	-	-	-	-	GO:0007165//signal transduction	--
ENSG00000284917	0	0	0	0	0	0	0	0	0	0	0	0	EEF1AKMT4-ECE2	EEF1AKMT4-ECE2 readthrough [Source:HGNC Symbol;Acc:HGNC:53615]	-	-	-	-	GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030658//transport vesicle membrane;GO:0031410//cytoplasmic vesicle	GO:0003824//catalytic activity;GO:0004222//metalloendopeptidase activity;GO:0008168//methyltransferase activity;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0016740//transferase activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	GO:0006508//proteolysis;GO:0007420//brain development;GO:0007507//heart development;GO:0008152//metabolic process;GO:0010002//cardioblast differentiation;GO:0016485//protein processing;GO:0032259//methylation	--
ENSG00000284922	0.182	0.295	1.651	0.131	0.274	0.207	13.62	18.2	28.03	7.25	10.62	10.32	LRTOMT	leucine rich transmembrane and O-methyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:25033]	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Nervous system;Lipid metabolism;Amino acid metabolism	ko01100//Metabolic pathways;ko04728//Dopaminergic synapse;ko00140//Steroid hormone biosynthesis;ko00350//Tyrosine metabolism	K00545;K00545;K00545;K00545	GO:0005575//cellular_component;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0016206//catechol O-methyltransferase activity;GO:0016740//transferase activity;GO:0102084//L-dopa O-methyltransferase activity;GO:0102938//orcinol O-methyltransferase activity	GO:0006584//catecholamine metabolic process;GO:0007605//sensory perception of sound;GO:0032259//methylation;GO:0032502//developmental process;GO:0042135//neurotransmitter catabolic process;GO:0042417//dopamine metabolic process;GO:0042420//dopamine catabolic process;GO:0042424//catecholamine catabolic process;GO:0060117//auditory receptor cell development	--
ENSG00000284931	0	0	0	0	0	0	0	0	0	0	0	0	HBG1	novel protein	-	-	-	-	GO:0005833//hemoglobin complex	GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0046872//metal ion binding	GO:0015671//oxygen transport	--
ENSG00000284934	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	Cellular Processes;Cellular Processes	Cell growth and death;Cell growth and death	ko04210//Apoptosis;ko04215//Apoptosis - multiple species	K10522;K10522	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284946	0.874	0.572	0.544	0.366	0.383	0.56	110.9	71.78	55.72	33.29	42.35	53.38	VPS33B	novel protein	-	-	-	-	GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane	-	GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000284952	0	0	0	0	0	0	0	0	0	0	0	0	SLC33A1	novel transcript	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00604//Glycosphingolipid biosynthesis - ganglio series	K03372;K03372	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008521//acetyl-CoA transmembrane transporter activity	GO:0015876//acetyl-CoA transport	--
ENSG00000284956	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000284969	0.4	0	0	0	0.218	0.134	4.75	0	0	0	2.19	1.16	CD59	novel protein	Organismal Systems;Organismal Systems	Immune system;Immune system	ko04640//Hematopoietic cell lineage;ko04610//Complement and coagulation cascades	K04008;K04008	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane	-	GO:0001971//negative regulation of activation of membrane attack complex	--
ENSG00000284976	0.299	0.544	1.117	0	0.842	0.307	11.84	21.67	32.68	0	28.19	8.86	--	novel RING finger protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding;GO:0061630//ubiquitin protein ligase activity	GO:0016567//protein ubiquitination	--
ENSG00000284981	0.382	0.527	0.165	0	0	0.325	7.97	11.04	2.54	0	0	4.93	UPK3BL2	uroplakin 3B like 2 [Source:HGNC Symbol;Acc:HGNC:53444]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000284987	0	0	0	0	0	0	0	0	0	0	0	0	ARHGAP4	novel transcript	-	-	-	-	-	-	-	--
ENSG00000284989	0	0.072	0	0.188	0	0	0	6.03	0	11.66	0	0	KDM4A	novel transcript	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000285000	1.974	1.822	1.464	1.846	1.374	2.335	96.12	89.2	52.65	66.59	56.55	82.75	AGGF1	"novel protein, AGGF1-ZBED3-AS1 readthrough"	-	-	-	-	-	GO:0003676//nucleic acid binding	GO:0045766//positive regulation of angiogenesis	--
ENSG00000285010	0	0	0	0	0	0	0	0	0	0	0	0	OOSP4A	oocyte secreted protein family member 4A [Source:HGNC Symbol;Acc:HGNC:53904]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000285025	0	0.324	0.092	0	0	0	0	1.44	0.3	0	0	0	MIEF1	novel protein	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005762//mitochondrial large ribosomal subunit	-	GO:0006417//regulation of translation;GO:0042254//ribosome biogenesis;GO:0070131//positive regulation of mitochondrial translation;GO:0071456//cellular response to hypoxia	--
ENSG00000285043	20.776	23.062	24.336	25.016	27.247	21.828	1001.36	1114.39	855.1	893.74	1086.27	762.16	--	novel protein	Metabolism;Environmental Information Processing;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Global and overview maps;Global and overview maps;Carbohydrate metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko01200//Carbon metabolism;ko01230//Biosynthesis of amino acids;ko00010//Glycolysis / Gluconeogenesis;ko00051//Fructose and mannose metabolism;ko00030//Pentose phosphate pathway	K01623;K01623;K01623;K01623;K01623;K01623;K01623	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000285053	1.203	1.154	0.852	1.093	1.095	1.865	59.13	57.67	30.91	39.78	45.47	66.67	TBCE	tubulin folding cofactor E [Source:HGNC Symbol;Acc:HGNC:11582]	-	-	-	-	GO:0005737//cytoplasm;GO:0005840//ribosome;GO:0005856//cytoskeleton;GO:0005874//microtubule	GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0043014//alpha-tubulin binding;GO:0051087//chaperone binding	GO:0000226//microtubule cytoskeleton organization;GO:0006412//translation;GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway;GO:0007052//mitotic spindle organization;GO:0008299//isoprenoid biosynthetic process	--
ENSG00000285064	0	0	0	0	0	0	0	0	0	0	0	0	SMIM40	novel protein	-	-	-	-	-	-	-	--
ENSG00000285077	0.066	0.036	0	0.05	0.065	0.358	4.44	2.41	0	2.48	3.72	17.58	ARHGAP11B	Rho GTPase activating protein 11B [Source:HGNC Symbol;Acc:HGNC:15782]	-	-	-	-	GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005829//cytosol	GO:0005096//GTPase activator activity;GO:0005515//protein binding	GO:0006543//glutamine catabolic process;GO:0007165//signal transduction;GO:0021987//cerebral cortex development;GO:0035795//negative regulation of mitochondrial membrane permeability;GO:0050790//regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000285082	0.073	0	0.099	0	0	0	2	0	2	0	0	0	TLR4	novel protein	Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases	Signal transduction;Infectious disease: viral;Infectious disease: bacterial;Immune system;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Infectious disease: viral;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Immune system;Signal transduction;Infectious disease: viral;Infectious disease: parasitic;Cell growth and death;Infectious disease: viral;Immune disease;Infectious disease: viral;Infectious disease: parasitic;Endocrine and metabolic disease;Signal transduction;Infectious disease: parasitic;Infectious disease: parasitic;Immune system;Cancer: overview;Infectious disease: bacterial;Immune disease;Infectious disease: bacterial;Infectious disease: parasitic	ko04151//PI3K-Akt signaling pathway;ko05171//Coronavirus disease - COVID-19;ko05130//Pathogenic Escherichia coli infection;ko04613//Neutrophil extracellular trap formation;ko05132//Salmonella infection;ko05131//Shigellosis;ko05152//Tuberculosis;ko04145//Phagosome;ko05170//Human immunodeficiency virus 1 infection;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko04621//NOD-like receptor signaling pathway;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05146//Amoebiasis;ko04217//Necroptosis;ko05161//Hepatitis B;ko05323//Rheumatoid arthritis;ko05162//Measles;ko05140//Leishmaniasis;ko04936//Alcoholic liver disease;ko04066//HIF-1 signaling pathway;ko05145//Toxoplasmosis;ko05142//Chagas disease;ko04620//Toll-like receptor signaling pathway;ko05235//PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05133//Pertussis;ko05321//Inflammatory bowel disease;ko05134//Legionellosis;ko05144//Malaria	K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160;K10160	GO:0016021//integral component of membrane	GO:0004888//transmembrane signaling receptor activity	GO:0002224//toll-like receptor signaling pathway;GO:0006955//immune response	--
ENSG00000285085	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000285130	0.222	0.366	0.307	0.175	0.181	0.26	15.8	25.69	20.31	11.64	12.46	15.31	TJP2	novel protein	Cellular Processes;Human Diseases	Cellular community - eukaryotes;Infectious disease: bacterial	ko04530//Tight junction;ko05110//Vibrio cholerae infection	K06098;K06098	GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0070160//tight junction	GO:0005515//protein binding;GO:0008199//ferric iron binding	GO:0016226//iron-sulfur cluster assembly;GO:0055072//iron ion homeostasis	--
ENSG00000285133	0	0	0	0	0	0	0	0	0	0	0	0	DDIT3	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005770//late endosome	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity	"GO:0006355//regulation of transcription, DNA-templated;GO:0006983//ER overload response;GO:0007605//sensory perception of sound;GO:0009611//response to wounding;GO:0010467//gene expression;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036119//response to platelet-derived growth factor;GO:0045599//negative regulation of fat cell differentiation;GO:0060840//artery development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1904738//vascular associated smooth muscle cell migration;GO:1990874//vascular associated smooth muscle cell proliferation"	--
ENSG00000285162	0.12	0.077	0.132	0.032	0	0	5.38	8.1	2	2.52	0	0	CHN2	novel protein	-	-	-	-	-	GO:0005096//GTPase activator activity	GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction	--
ENSG00000285171	0	0	0	0	0	0	0	0	0	0	0	0	IL2RG	"novel protein, IL2RG-CXorf65 readthrough"	Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems;Human Diseases	Cancer: overview;Signal transduction;Signaling molecules and interaction;Transport and catabolism;Infectious disease: viral;Signal transduction;Infectious disease: viral;Immune disease;Immune system;Signaling molecules and interaction;Immune system;Immune disease	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko04060//Cytokine-cytokine receptor interaction;ko04144//Endocytosis;ko05166//Human T-cell leukemia virus 1 infection;ko04630//JAK-STAT signaling pathway;ko05162//Measles;ko05340//Primary immunodeficiency;ko04659//Th17 cell differentiation;ko04061//Viral protein interaction with cytokine and cytokine receptor;ko04658//Th1 and Th2 cell differentiation;ko05321//Inflammatory bowel disease	K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070;K05070	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004896//cytokine receptor activity	GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000285188	0.069	0.066	0	0.207	0.077	0.2	8.61	8.26	0	19	8.04	18.02	PDE4C	novel protein	Metabolism;Environmental Information Processing;Metabolism;Organismal Systems;Human Diseases	Global and overview maps;Signal transduction;Nucleotide metabolism;Endocrine system;Substance dependence	"ko01100//Metabolic pathways;ko04024//cAMP signaling pathway;ko00230//Purine metabolism;ko04928//Parathyroid hormone synthesis, secretion and action;ko05032//Morphine addiction"	K13293;K13293;K13293;K13293;K13293	-	"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0008081//phosphoric diester hydrolase activity"	GO:0007165//signal transduction	--
ENSG00000285218	0	0	0	0.081	0	0	0	0	0	1.41	0	0	CLDN11	novel protein	Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Organismal Systems	Infectious disease: bacterial;Cellular community - eukaryotes;Infectious disease: viral;Signaling molecules and interaction;Immune system	ko05130//Pathogenic Escherichia coli infection;ko04530//Tight junction;ko05160//Hepatitis C;ko04514//Cell adhesion molecules;ko04670//Leukocyte transendothelial migration	K06087;K06087;K06087;K06087;K06087	GO:0005886//plasma membrane;GO:0005923//bicellular tight junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction	GO:0005198//structural molecule activity	-	--
ENSG00000285231	0	0	0.077	0	0	0	0	0	1	0	0	0	OOSP3	oocyte secreted protein family member 3 [Source:HGNC Symbol;Acc:HGNC:53903]	-	-	-	-	GO:0005576//extracellular region	-	-	--
ENSG00000285238	2.052	3.694	3.99	0	4.319	2.061	100.28	181.43	153.35	0.01	178.3	73.28	CHD4	novel transcript	Human Diseases;Human Diseases	Infectious disease: viral;Cancer: overview	ko05165//Human papillomavirus infection;ko05203//Viral carcinogenesis	K11643;K11643	GO:0043233//organelle lumen	GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding;GO:0140658//ATP-dependent chromatin remodeler activity	GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0032508//DNA duplex unwinding	--
ENSG00000285245	0.451	0.278	0	0.252	0	0	34.68	21.45	0	14.33	0	0	RALGDS	novel protein	Human Diseases;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Signal transduction;Signal transduction;Signal transduction;Cancer: overview;Cancer: specific types;Cancer: specific types	ko05200//Pathways in cancer;ko04014//Ras signaling pathway;ko04015//Rap1 signaling pathway;ko04072//Phospholipase D signaling pathway;ko05231//Choline metabolism in cancer;ko05210//Colorectal cancer;ko05212//Pancreatic cancer	K08732;K08732;K08732;K08732;K08732;K08732;K08732	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000285253	1.027	0.936	0.917	0.524	0.801	0.682	107.57	98.56	70.92	40.68	70.89	52	ZNF280D	novel protein	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000285269	0.237	0.301	0.12	0	0.243	0.093	16.39	20.9	6.14	0	14.17	4.68	SLC35D2	"novel transcript, SLC35D2-HSD17B3 readthrough"	-	-	-	-	GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005461//UDP-glucuronic acid transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005463//UDP-N-acetylgalactosamine transmembrane transporter activity;GO:0015297//antiporter activity	GO:0015787//UDP-glucuronic acid transmembrane transport;GO:0015789//UDP-N-acetylgalactosamine transmembrane transport;GO:0055085//transmembrane transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport	--
ENSG00000285283	0	0	0	1.609	0	0	0	0	0	29.45	0	0	RCN1	novel protein	-	-	-	-	GO:0005783//endoplasmic reticulum	GO:0005509//calcium ion binding	-	--
ENSG00000285292	8.225	10.604	11.451	9.485	11.585	9.653	372.77	483.06	383.3	318.42	443.59	318.33	ABCF2-H2BE1	ABCF2-H2BE1 readthrough [Source:HGNC Symbol;Acc:HGNC:54751]	Human Diseases	Infectious disease: bacterial	ko05130//Pathogenic Escherichia coli infection	K06185	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding	-	--
ENSG00000285304	0.05	1.129	0.125	0.663	1.239	0	3.27	73.49	5.99	31.81	67.81	0	BARGIN	novel protein	-	-	-	-	GO:0005737//cytoplasm	GO:0005515//protein binding	GO:0007165//signal transduction	--
ENSG00000285329	0	0	0	0.232	0	0	0	0	0	2	0	0	ZNF174	novel protein	-	-	-	-	-	GO:0003700//DNA-binding transcription factor activity	GO:0000122//negative regulation of transcription by RNA polymerase II	--
ENSG00000285330	0.675	0	0	0	0.377	2.169	33.41	0	0	0	15.74	78.07	CFI	novel protein	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K01333;K01333	GO:0005576//extracellular region;GO:0016020//membrane	GO:0004252//serine-type endopeptidase activity;GO:0004623//phospholipase A2 activity;GO:0005044//scavenger receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0006508//proteolysis;GO:0006897//endocytosis;GO:0016042//lipid catabolic process	--
ENSG00000285382	0.387	0.223	0.312	0.419	0.119	0.454	23.11	14.09	14.14	18.12	6.64	19.91	COMMD7	novel protein	-	-	-	-	-	-	-	--
ENSG00000285404	0	0	0.009	0	0	0.266	0	0	0.27	0	0	7.69	DEPDC5	"novel protein, DEPDC5-YWHAH readthrough"	Environmental Information Processing	Signal transduction	ko04150//mTOR signaling pathway	K20404	GO:0005737//cytoplasm	GO:0005096//GTPase activator activity	GO:0050790//regulation of catalytic activity	--
ENSG00000285437	1.538	1.023	1.487	1.399	5.684	4.927	61.22	44.22	51.91	68.3	97.78	99.29	POLR2J3	RNA polymerase II subunit J3 [Source:HGNC Symbol;Acc:HGNC:33853]	Human Diseases;Genetic Information Processing	Neurodegenerative disease;Transcription	ko05016//Huntington disease;ko03020//RNA polymerase	K03008;K03008	"GO:0005634//nucleus;GO:0005665//RNA polymerase II, core complex"	GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0046983//protein dimerization activity	"GO:0006351//transcription, DNA-templated;GO:0006366//transcription by RNA polymerase II"	--
ENSG00000285444	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000285446	0	0	0	0	0	0	0	0	0	0	0	0	DSE	novel protein	Metabolism;Metabolism	Global and overview maps;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00532//Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	K01794;K01794	-	GO:0016853//isomerase activity;GO:0047757//chondroitin-glucuronate 5-epimerase activity	GO:0030204//chondroitin sulfate metabolic process;GO:0030205//dermatan sulfate metabolic process	--
ENSG00000285458	0.314	0.291	0.075	0.345	0.619	0.316	15	14	2.66	12.21	25	11	C4orf36	novel protein	-	-	-	-	-	-	-	--
ENSG00000285471	0.072	0.081	0	0	0	0	1.14	1.28	0	0	0	0	WSCD1	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000285472	0	0	0	0	0	0	0	0	0	0	0	0	OR4N4	novel protein	Organismal Systems	Sensory system	ko04740//Olfactory transduction	K04257	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0004930//G protein-coupled receptor activity;GO:0004984//olfactory receptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050896//response to stimulus;GO:0050911//detection of chemical stimulus involved in sensory perception of smell	--
ENSG00000285476	0	0	0	0	0	0	0	0	0	0	0	0	FAM153B	novel transcript	-	-	-	-	-	-	-	--
ENSG00000285480	0	0	0	0	0	0	0	0	0	0	0	0	H2BE1	H2B.E variant histone 1 [Source:HGNC Symbol;Acc:HGNC:53833]	Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Immune system;Immune disease;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11252;K11252;K11252;K11252	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome	GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity	GO:0006334//nucleosome assembly	--
ENSG00000285505	0.449	0	0.224	0.38	0	0	32.9	0	12.14	20.66	0	0	ATP1A3	"novel protein, ATP1A3-RABAC1 readthrough"	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems;Organismal Systems	Signal transduction;Signal transduction;Circulatory system;Endocrine system;Digestive system;Digestive system;Endocrine system;Digestive system;Digestive system;Circulatory system;Endocrine system;Digestive system;Endocrine system;Digestive system;Excretory system;Digestive system;Excretory system;Excretory system	ko04024//cAMP signaling pathway;ko04022//cGMP-PKG signaling pathway;ko04261//Adrenergic signaling in cardiomyocytes;ko04919//Thyroid hormone signaling pathway;ko04972//Pancreatic secretion;ko04974//Protein digestion and absorption;ko04925//Aldosterone synthesis and secretion;ko04970//Salivary secretion;ko04976//Bile secretion;ko04260//Cardiac muscle contraction;ko04911//Insulin secretion;ko04971//Gastric acid secretion;ko04918//Thyroid hormone synthesis;ko04978//Mineral absorption;ko04961//Endocrine and other factor-regulated calcium reabsorption;ko04973//Carbohydrate digestion and absorption;ko04960//Aldosterone-regulated sodium reabsorption;ko04964//Proximal tubule bicarbonate reclamation	K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539;K01539	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0000166//nucleotide binding;GO:0005524//ATP binding;GO:0008556//P-type potassium transmembrane transporter activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0071805//potassium ion transmembrane transport	--
ENSG00000285508	0	0	0	0	0	0	0	0	0	0	0	0	MKKS	MKKS centrosomal shuttling protein [Source:NCBI gene (formerly Entrezgene);Acc:8195]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000285509	0.193	0.125	0.249	0.216	0.346	0.093	5.74	3.72	5.47	4.75	8.68	2	TBCEL-TECTA	TBCEL-TECTA readthrough [Source:HGNC Symbol;Acc:HGNC:54857]	-	-	-	-	GO:0005737//cytoplasm	GO:0043014//alpha-tubulin binding	GO:0000226//microtubule cytoskeleton organization;GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway;GO:0007160//cell-matrix adhesion	--
ENSG00000285526	0	0.168	0	0	0	0	0	6.25	0	0	0	0	FXYD3	novel protein	-	-	-	-	GO:0016020//membrane	GO:0099106//ion channel regulator activity	GO:0043269//regulation of ion transport	--
ENSG00000285528	0	0	0	0	0.025	0	0	0	0	0	1	0	GLS2	novel protein	Metabolism;Human Diseases;Organismal Systems;Organismal Systems;Human Diseases;Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Nervous system;Nervous system;Cancer: overview;Amino acid metabolism;Excretory system;Amino acid metabolism;Metabolism of other amino acids	"ko01100//Metabolic pathways;ko05206//MicroRNAs in cancer;ko04724//Glutamatergic synapse;ko04727//GABAergic synapse;ko05230//Central carbon metabolism in cancer;ko00250//Alanine, aspartate and glutamate metabolism;ko04964//Proximal tubule bicarbonate reclamation;ko00220//Arginine biosynthesis;ko00470//D-Amino acid metabolism"	K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425;K01425	-	-	-	--
ENSG00000285542	0.043	0	0	0	0	0	2.94	0	0	0	0	0	PPM1B	"novel protein, PPM1B-SLC3A1 readthrough"	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04010//MAPK signaling pathway;ko04013//MAPK signaling pathway - fly	K04461;K04461	GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0110165//cellular anatomical entity	GO:0000287//magnesium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity;GO:0030145//manganese ion binding;GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0106306//protein serine phosphatase activity;GO:0106307//protein threonine phosphatase activity	GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation	--
ENSG00000285547	0.107	0.074	0.267	0	0.532	0	3.89	2.92	7.16	0	16.33	0	HDAC8	novel protein	Organismal Systems;Human Diseases;Human Diseases	Immune system;Cancer: overview;Substance dependence	ko04613//Neutrophil extracellular trap formation;ko05203//Viral carcinogenesis;ko05034//Alcoholism	K11405;K11405;K11405	GO:0005634//nucleus	GO:0004407//histone deacetylase activity;GO:0016787//hydrolase activity	"GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation"	--
ENSG00000285558	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000285566	0	0	0	0	0	0	0	0	0	0	0	0	--	novel keratin-associated protein	-	-	-	-	-	-	GO:0001942//hair follicle development	--
ENSG00000285585	0	0	0	0	0	0	0	0	0	0	0	0	MAATS1	novel protein	-	-	-	-	-	-	-	--
ENSG00000285589	0.895	1.122	1.297	1.126	1.245	1.359	93.33	117.56	99.82	86.9	109.67	103.08	DHPS	novel transcript	-	-	-	-	-	-	GO:0008612//peptidyl-lysine modification to peptidyl-hypusine	--
ENSG00000285602	0.203	0.347	0.283	0.074	0.155	0.174	15.41	26.51	15.9	4.14	9.96	9.64	CLTRN	novel protein	-	-	-	-	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	-	-	--
ENSG00000285607	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A9P	"family with sequence similarity 90 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:32257]"	-	-	-	-	-	-	-	--
ENSG00000285620	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A16P	"family with sequence similarity 90 member A16, pseudogene [Source:HGNC Symbol;Acc:HGNC:32264]"	-	-	-	-	-	-	-	--
ENSG00000285625	0	0	0	0	0	0	0	0	0	0	0	0	PRIM1	novel protein	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02684	-	GO:0003896//DNA primase activity;GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0016740//transferase activity;GO:0016779//nucleotidyltransferase activity;GO:0046872//metal ion binding	"GO:0006260//DNA replication;GO:0006269//DNA replication, synthesis of RNA primer"	--
ENSG00000285629	0	0.08	0	0	0	0	0	1.1	0	0	0	0	RPL22	novel transcript	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02891;K02891	GO:0005737//cytoplasm;GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation	--
ENSG00000285635	0	0	0	0	0	0	0	0	0	0	0	0	CPOX	novel transcript	Metabolism;Metabolism	Global and overview maps;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko00860//Porphyrin metabolism	K00228;K00228	GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space	GO:0004109//coproporphyrinogen oxidase activity;GO:0016491//oxidoreductase activity	GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006782//protoporphyrinogen IX biosynthetic process	--
ENSG00000285641	3.905	3.188	4.237	5.38	4.259	4.228	138.17	113.39	110.73	141.01	127.34	108.85	RAB13	novel protein	Cellular Processes	Cellular community - eukaryotes	ko04530//Tight junction	K06109	-	-	-	--
ENSG00000285645	0	0	0	0	0	0	0	0	0	0	0	0	FAM221B	Novel protein	-	-	-	-	-	-	-	--
ENSG00000285655	0	0	0	0	0	0	0	0	0	0	0	0	ADHFE1	novel protein	-	-	-	-	GO:0005739//mitochondrion	GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding	-	--
ENSG00000285657	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A19P	"family with sequence similarity 90 member A19, pseudogene [Source:HGNC Symbol;Acc:HGNC:32267]"	-	-	-	-	-	-	-	--
ENSG00000285687	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A22P	"family with sequence similarity 90 member A22, pseudogene [Source:HGNC Symbol;Acc:HGNC:32270]"	-	-	-	-	-	-	-	--
ENSG00000285708	0.314	0	0.021	0.681	0	0.232	4.83	0	0.24	7.76	0	2.6	FOXP1	novel protein	Human Diseases	Cancer: overview	ko05206//MicroRNAs in cancer	K23582	GO:0005634//nucleus	GO:0003677//DNA binding;GO:0003700//DNA-binding transcription factor activity;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated;GO:0006413//translational initiation;GO:0048513//animal organ development"	--
ENSG00000285713	0.128	0.079	0.037	0.143	0	0.076	5	3.12	1.06	4.16	0	2.16	ANAPC10	novel transcript	Human Diseases;Genetic Information Processing;Cellular Processes;Cellular Processes;Organismal Systems	"Infectious disease: viral;Folding, sorting and degradation;Cell growth and death;Cell growth and death;Endocrine system"	ko05166//Human T-cell leukemia virus 1 infection;ko04120//Ubiquitin mediated proteolysis;ko04114//Oocyte meiosis;ko04110//Cell cycle;ko04914//Progesterone-mediated oocyte maturation	K03357;K03357;K03357;K03357;K03357	GO:0005680//anaphase-promoting complex	-	GO:0007049//cell cycle;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division	--
ENSG00000285720	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A17P	"family with sequence similarity 90 member A17, pseudogene [Source:HGNC Symbol;Acc:HGNC:32265]"	-	-	-	-	-	-	-	--
ENSG00000285723	1.102	0.217	0	0.641	0.279	0	4.39	0.87	0	1.89	0.94	0	MKKS	MKKS centrosomal shuttling protein [Source:NCBI gene (formerly Entrezgene);Acc:8195]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000285733	0	0	0.03	0	0	0	0	0	1	0	0	0	WDR27	novel protein	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000285749	0	0	0	0	0	0	0	0	0	0	0	0	IQCF3	novel protein	-	-	-	-	-	GO:0005515//protein binding;GO:0005516//calmodulin binding	-	--
ENSG00000285762	0	0	0.159	0.327	0	0	0	0	1.96	4.04	0	0	DDT	"novel protein, AP000351.4-DDT readtrhough"	-	-	-	-	-	-	-	--
ENSG00000285765	0	0.075	0	0	0	0	0	2.18	0	0	0	0	FAM90A23P	"family with sequence similarity 90 member A23, pseudogene [Source:HGNC Symbol;Acc:HGNC:32271]"	-	-	-	-	-	-	-	--
ENSG00000285772	0	0	0	0	0	0	0	0	0	0	0	0	CYP51A1	novel protein	-	-	-	-	-	-	-	--
ENSG00000285777	0	0.304	0.205	0.067	0	0	0	11.31	5.6	1.83	0	0	ANKRD45	novel protein	-	-	-	-	-	-	-	--
ENSG00000285779	0	0	0	0	0	0	0	0	0	0	0	0	JTB	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030496//midbody	-	GO:0000281//mitotic cytokinesis	--
ENSG00000285791	0.088	0.167	0.129	0.065	0.05	0.144	8.97	17.11	9.72	4.91	4.27	10.67	ADHFE1	novel transcript	-	-	-	-	GO:0005739//mitochondrion	GO:0004022//alcohol dehydrogenase (NAD+) activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0047988//hydroxyacid-oxoacid transhydrogenase activity	-	--
ENSG00000285814	0.069	0.063	0	0	0	0	2	1.82	0	0	0	0	FAM90A14P	"family with sequence similarity 90 member A14, pseudogene [Source:HGNC Symbol;Acc:HGNC:32262]"	-	-	-	-	-	-	-	--
ENSG00000285815	0.322	0.39	0.374	0	0.051	0.16	8.87	10.8	7.61	0	1.71	3.2	GET1-SH3BGR	GET1-SH3BGR readthrough [Source:HGNC Symbol;Acc:HGNC:54635]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0071816//tail-anchored membrane protein insertion into ER membrane	--
ENSG00000285816	1.713	1.002	1.477	0.71	0.787	1.024	151.22	88.89	96.31	46.4	58.71	65.8	POLA2	"novel protein, POLA2-CDC42EP2 readthrough"	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K02321	GO:0005634//nucleus	GO:0003677//DNA binding	GO:0006259//DNA metabolic process;GO:0006260//DNA replication	--
ENSG00000285827	0	0.072	0.053	0	0	0	0	3.32	1.81	0	0	0	KMT2A	novel protein	Metabolism;Human Diseases;Human Diseases;Metabolism	Global and overview maps;Cancer: overview;Endocrine and metabolic disease;Amino acid metabolism	ko01100//Metabolic pathways;ko05202//Transcriptional misregulation in cancer;ko04934//Cushing syndrome;ko00310//Lysine degradation	K09186;K09186;K09186;K09186	"GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005739//mitochondrion;GO:0016020//membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0071339//MLL1 complex"	GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0015078//proton transmembrane transporter activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0046872//metal ion binding	GO:0006811//ion transport;GO:0015986//ATP synthesis coupled proton transport;GO:0051568//histone H3-K4 methylation	--
ENSG00000285837	0	0	0	0	0	0	0	0	0	0	0	0	ZNF365	novel protein	-	-	-	-	-	-	-	--
ENSG00000285839	0	0	0	0	0	0	0	0	0	0	0	0	KTI12	novel transcript	-	-	-	-	-	GO:0000166//nucleotide binding;GO:0005524//ATP binding	GO:0002098//tRNA wobble uridine modification;GO:0006357//regulation of transcription by RNA polymerase II	--
ENSG00000285843	0	0	0	0	0	0	0	0	0	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000285854	0.016	0.016	0	0.043	0.019	0	1.24	1.24	0	2.49	1.24	0	LDHB	novel transcript	Metabolism;Environmental Information Processing;Organismal Systems;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Signal transduction;Endocrine system;Cancer: overview;Carbohydrate metabolism;Amino acid metabolism;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko04066//HIF-1 signaling pathway;ko04922//Glucagon signaling pathway;ko05230//Central carbon metabolism in cancer;ko00010//Glycolysis / Gluconeogenesis;ko00270//Cysteine and methionine metabolism;ko00620//Pyruvate metabolism;ko00640//Propanoate metabolism	K00016;K00016;K00016;K00016;K00016;K00016;K00016;K00016	GO:0005737//cytoplasm	"GO:0003824//catalytic activity;GO:0004459//L-lactate dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"	GO:0019752//carboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process	--
ENSG00000285868	0	0	0	0.028	0	0	0	0	0	1.81	0	0	FNDC9	Novel protein	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000285880	0	0	0	0	0	0	0	0	0	0	0	0	ADRB3	ADRB3-GOT1L1 readthrough	Environmental Information Processing;Environmental Information Processing;Organismal Systems;Human Diseases;Environmental Information Processing;Organismal Systems;Organismal Systems;Organismal Systems	Signaling molecules and interaction;Signal transduction;Environmental adaptation;Cancer: overview;Signal transduction;Digestive system;Endocrine system;Endocrine system	ko04080//Neuroactive ligand-receptor interaction;ko04020//Calcium signaling pathway;ko04714//Thermogenesis;ko05207//Chemical carcinogenesis - receptor activation;ko04022//cGMP-PKG signaling pathway;ko04970//Salivary secretion;ko04924//Renin secretion;ko04923//Regulation of lipolysis in adipocytes	K04143;K04143;K04143;K04143;K04143;K04143;K04143;K04143	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0004930//G protein-coupled receptor activity;GO:0004939//beta-adrenergic receptor activity;GO:0015052//beta3-adrenergic receptor activity;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding	GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway	--
ENSG00000285891	0	0	0	0	0	0	0	0	0	0	0	0	MSANTD5	Myb/SANT DNA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:55184]	-	-	-	-	-	-	-	--
ENSG00000285897	0.033	0	0	0.071	0	0	3.99	0	0	6.34	0	0	RNF43	novel transcript	Environmental Information Processing	Signal transduction	ko04310//Wnt signaling pathway	K15694	GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0016740//transferase activity;GO:0046872//metal ion binding	GO:0016567//protein ubiquitination	--
ENSG00000285901	2.318	2.296	1.614	1.93	0.996	2	165.13	164.4	84.94	101.87	59.93	103.69	CCND2	novel transcript	Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Environmental Information Processing;Cellular Processes;Organismal Systems;Cellular Processes;Environmental Information Processing	Cancer: overview;Signal transduction;Infectious disease: viral;Infectious disease: viral;Cancer: overview;Infectious disease: viral;Cancer: overview;Cellular community - eukaryotes;Cancer: overview;Signal transduction;Signal transduction;Cell growth and death;Signal transduction;Infectious disease: viral;Signal transduction;Cell growth and death;Endocrine system;Cell growth and death;Signal transduction	ko05200//Pathways in cancer;ko04151//PI3K-Akt signaling pathway;ko05165//Human papillomavirus infection;ko05169//Epstein-Barr virus infection;ko05202//Transcriptional misregulation in cancer;ko05166//Human T-cell leukemia virus 1 infection;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko05206//MicroRNAs in cancer;ko04310//Wnt signaling pathway;ko04630//JAK-STAT signaling pathway;ko04218//Cellular senescence;ko04390//Hippo signaling pathway;ko05162//Measles;ko04068//FoxO signaling pathway;ko04110//Cell cycle;ko04917//Prolactin signaling pathway;ko04115//p53 signaling pathway;ko04340//Hedgehog signaling pathway	K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151;K10151	GO:0016020//membrane	-	-	--
ENSG00000285913	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A18P	"family with sequence similarity 90 member A18, pseudogene [Source:HGNC Symbol;Acc:HGNC:32266]"	-	-	-	-	-	-	-	--
ENSG00000285920	0	0	0	0	0	0.07	0	0	0	0	0	3.19	NUSAP1	novel protein	-	-	-	-	GO:0005819//spindle;GO:0005874//microtubule	-	GO:0000226//microtubule cytoskeleton organization;GO:0000281//mitotic cytokinesis;GO:0040001//establishment of mitotic spindle localization	--
ENSG00000285932	0	0.044	0	0.055	0.168	0.324	0	1.82	0	1.68	5.81	9.65	COX15	novel transcript	Metabolism;Organismal Systems;Metabolism;Metabolism	Global and overview maps;Environmental adaptation;Energy metabolism;Metabolism of cofactors and vitamins	ko01100//Metabolic pathways;ko04714//Thermogenesis;ko00190//Oxidative phosphorylation;ko00860//Porphyrin metabolism	K02259;K02259;K02259;K02259	GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"	GO:0006784//heme A biosynthetic process	--
ENSG00000285937	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A8P	"family with sequence similarity 90 member A8, pseudogene [Source:HGNC Symbol;Acc:HGNC:32256]"	-	-	-	-	-	-	-	--
ENSG00000285938	0	0	0	0	0	0.116	0	0	0	0	0	2	--	BCL6 antisense 1	-	-	-	-	-	-	-	--
ENSG00000285942	0	0	0	0.334	0	0	0	0	0	13.07	0	0	LRRC57	novel protein	-	-	-	-	-	-	-	--
ENSG00000285943	0.29	0.275	0.225	0.069	0.54	0.224	41.08	39.15	23.59	7.26	64.67	23.12	SPICE1	novel protein	-	-	-	-	-	-	-	--
ENSG00000285946	0	0	0	0	0	0	0	0	0	0	0	0	--	novel late cornified envelope family protein	-	-	-	-	-	-	GO:0008544//epidermis development;GO:0031424//keratinization	--
ENSG00000285947	0	0.046	0	0	0	0.128	0	1	0	0	0	2	GH1	novel protein	Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Environmental Information Processing;Organismal Systems	Signal transduction;Signaling molecules and interaction;Signaling molecules and interaction;Signal transduction;Endocrine system	"ko04151//PI3K-Akt signaling pathway;ko04080//Neuroactive ligand-receptor interaction;ko04060//Cytokine-cytokine receptor interaction;ko04630//JAK-STAT signaling pathway;ko04935//Growth hormone synthesis, secretion and action"	K05438;K05438;K05438;K05438;K05438	GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle	GO:0004888//transmembrane signaling receptor activity;GO:0005131//growth hormone receptor binding;GO:0005179//hormone activity;GO:0008083//growth factor activity	GO:0007166//cell surface receptor signaling pathway;GO:0031667//response to nutrient levels;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045927//positive regulation of growth;GO:0046427//positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513//animal organ development;GO:0060396//growth hormone receptor signaling pathway	--
ENSG00000285950	0	0	0	0	0	0	0	0	0	0	0	0	FAM90A10P	"family with sequence similarity 90 member A10, pseudogene [Source:HGNC Symbol;Acc:HGNC:32258]"	-	-	-	-	-	-	-	--
ENSG00000285953	0	0	0	0	0	0	0	0	0	0	0	0	KRIT1	novel protein	Environmental Information Processing;Organismal Systems	Signal transduction;Aging	ko04015//Rap1 signaling pathway;ko04212//Longevity regulating pathway - worm	K17705;K17705	GO:0005856//cytoskeleton;GO:0005886//plasma membrane	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding"	GO:0007165//signal transduction;GO:0016525//negative regulation of angiogenesis;GO:0045454//cell redox homeostasis;GO:2000114//regulation of establishment of cell polarity	--
ENSG00000285975	0	0	0	0	0.082	0	0	0	0	0	2	0	FAM90A7P	"family with sequence similarity 90 member A7, pseudogene [Source:HGNC Symbol;Acc:HGNC:32255]"	-	-	-	-	-	-	-	--
ENSG00000285976	0.106	0.406	0	0.099	0	0.107	9.91	38.05	0.02	6.86	0.03	7.24	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000285978	0	0	0.12	0	0.07	0	0	0	3.03	0	2.04	0	ZNF354A	novel transcript	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000285982	0	0	0	0	0	0	0	0	0	0	0	0	SLC25A32	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane	-	GO:0006839//mitochondrial transport;GO:0006862//nucleotide transport;GO:0055085//transmembrane transport	--
ENSG00000285991	0	0	0	0	0	0	0	0	0	0	0	0	RAET1E	novel transcript	Organismal Systems	Immune system	ko04650//Natural killer cell mediated cytotoxicity	K07987	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000286001	0.206	0.406	0.317	0.734	0.447	0.777	15.65	31	17.8	41.31	28.72	42.95	SDHA	novel protein	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Metabolism;Metabolism;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Energy metabolism;Global and overview maps;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko00190//Oxidative phosphorylation;ko01200//Carbon metabolism;ko00020//Citrate cycle (TCA cycle)	K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234;K00234	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane	GO:0016491//oxidoreductase activity	GO:0006099//tricarboxylic acid cycle	--
ENSG00000286007	0	0	0	0	0	0	0	0	0	0	0	0	SPEM3	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000286014	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE15	speedy/RINGO cell cycle regulator family member E15 [Source:HGNC Symbol;Acc:HGNC:51511]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000286015	0	0	0	0	0	0	0	0	0	0	0	0	LYPD8	novel protein	-	-	-	-	-	-	-	--
ENSG00000286019	3.158	2.526	2.034	2.794	2.137	1.489	72.58	58.35	34.52	47.56	41.49	24.9	NOTCH2NLB	notch 2 N-terminal like B [Source:HGNC Symbol;Acc:HGNC:53923]	-	-	-	-	GO:0005576//extracellular region	GO:0005112//Notch binding;GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0021987//cerebral cortex development;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000286022	0	0	0	0	0	0	0	0	0	0	0	0	TGM3	novel protein	-	-	-	-	-	GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding	GO:0018149//peptide cross-linking	--
ENSG00000286025	0	0.056	0.038	0	0	0	0	2	1	0	0	0	-	-	-	-	-	-	-	-	-	-
ENSG00000286038	0	0	0	0	0	0	0	0	0	0	0	0	SPDYE13	speedy/RINGO cell cycle regulator family member E13 [Source:HGNC Symbol;Acc:HGNC:51509]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000286053	3.184	6.34	4.331	2.44	0.877	2.585	40.71	84.23	42.66	24.11	9.67	25.09	ASDURF	ASNSD1 upstream open reading frame [Source:HGNC Symbol;Acc:HGNC:53619]	-	-	-	-	GO:0005737//cytoplasm;GO:1990062//RPAP3/R2TP/prefoldin-like complex	-	GO:0050821//protein stabilization	--
ENSG00000286070	21.833	20.975	27.329	21.602	20.909	24.763	329.52	319.76	299.34	237.31	261.98	291.86	SNRPD3	novel protein	Human Diseases;Genetic Information Processing	Immune disease;Transcription	ko05322//Systemic lupus erythematosus;ko03040//Spliceosome	K11088;K11088	GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005829//cytosol	-	GO:0000387//spliceosomal snRNP assembly;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing	--
ENSG00000286075	0	0	1.053	0.038	0	0	0	0	3.34	0.12	0	0	SMIM10L2A	novel protein	-	-	-	-	-	-	-	--
ENSG00000286088	0	0	0	0	0	0	0	0	0	0	0	0	CUZD1	novel protein	-	-	-	-	-	-	-	--
ENSG00000286095	0	0	0	0	0	0	0	0	0	0	0	0	SPEGNB	SPEG neighbor [Source:HGNC Symbol;Acc:HGNC:51251]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000286098	0.704	0.083	0.531	0.572	0.606	0.333	46.97	5.54	26.17	28.26	34.14	16.14	ZNF844	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	-	--
ENSG00000286102	0	0	0	0	0	0	0	0	0	0	0	0	FAM246A	family with sequence similarity 246 member A [Source:HGNC Symbol;Acc:HGNC:54844]	-	-	-	-	-	-	-	--
ENSG00000286105	0	0.11	0	0	0.038	0	0	2	0	0	0.58	0	--	novel transmembrane protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000286106	2.955	2.953	1.733	2.353	2.4	2.655	70.21	70.83	31.32	41.19	48.19	47.43	NOTCH2NLR	notch 2 N-terminal like R (pseudogene) [Source:HGNC Symbol;Acc:HGNC:53925]	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Organismal Systems;Environmental Information Processing;Organismal Systems	Cancer: overview;Infectious disease: viral;Cancer: overview;Cancer: overview;Cancer: specific types;Endocrine system;Drug resistance: antineoplastic;Immune system;Signal transduction;Development and regeneration	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko05207//Chemical carcinogenesis - receptor activation;ko05206//MicroRNAs in cancer;ko05224//Breast cancer;ko04919//Thyroid hormone signaling pathway;ko01522//Endocrine resistance;ko04658//Th1 and Th2 cell differentiation;ko04330//Notch signaling pathway;ko04320//Dorso-ventral axis formation	K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994;K20994	-	GO:0005509//calcium ion binding	-	--
ENSG00000286112	0.311	0.541	0.509	0.403	0.382	0.34	44.94	78.6	54.33	43.17	46.71	35.73	KYAT1	Novel protein	Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Amino acid metabolism;Amino acid metabolism;Metabolism of other amino acids	ko01100//Metabolic pathways;ko00270//Cysteine and methionine metabolism;ko00380//Tryptophan metabolism;ko00450//Selenocompound metabolism	K00816;K00816;K00816;K00816	-	GO:0003824//catalytic activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0047804//cysteine-S-conjugate beta-lyase activity;GO:0070548//L-glutamine aminotransferase activity	GO:0006575//cellular modified amino acid metabolic process;GO:0009058//biosynthetic process;GO:0070189//kynurenine metabolic process;GO:0097052//L-kynurenine metabolic process	--
ENSG00000286131	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000286132	0.691	0.516	0.414	0.578	0.674	0.599	75.22	56.47	33.31	46.61	61.99	47.47	ZNF844	novel protein	Human Diseases	Infectious disease: viral	ko05168//Herpes simplex virus 1 infection	K09228	-	-	-	--
ENSG00000286135	0	0	0	0	0	0	0	0	0	0	0	0	SPADH1	novel protein similar to AQN-1 protein AQN-1 (Sus scrofa)	-	-	-	-	-	-	-	--
ENSG00000286137	0.022	0	0	0.058	0.028	0	1	0	0	1.92	1.06	0	SPDYE14	speedy/RINGO cell cycle regulator family member E14 [Source:HGNC Symbol;Acc:HGNC:51510]	Cellular Processes;Organismal Systems	Cell growth and death;Endocrine system	ko04114//Oocyte meiosis;ko04914//Progesterone-mediated oocyte maturation	K08694;K08694	-	GO:0019901//protein kinase binding	GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity	--
ENSG00000286140	7.682	9.119	9.288	12.157	11.089	10.949	446.64	532.89	398.41	521.88	544.71	462.84	DERPC	DERPC proline and glycine rich nuclear protein [Source:HGNC Symbol;Acc:HGNC:54084]	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular exosome	-	-	--
ENSG00000286143	0	0	0	0	0.105	0.191	0	0	0	0	2	3.13	SPEGNB	novel protein	-	-	-	-	-	GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding	GO:0006468//protein phosphorylation	--
ENSG00000286165	0.103	0	0	0.657	0	0	1.58	0	0	7.48	0	0	ASNSD1	novel protein	-	-	-	-	-	-	-	--
ENSG00000286175	0	0	0	0	0	0	0	0	0	0	0	0	FAM246B	family with sequence similarity 246 member B [Source:HGNC Symbol;Acc:HGNC:54843]	-	-	-	-	-	-	-	--
ENSG00000286185	0.036	0.08	0	0	0	0.026	10.78	23.91	0	0	0	5.61	NBPF19	"novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19"	-	-	-	-	-	-	-	--
ENSG00000286190	27.802	25.421	25.632	24.169	24.804	23.677	865	795	589	557	652	536	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000286192	0	0	0.055	0	0	0	0	0	4.81	0	0	0	MRM2	Novel protein	-	-	-	-	-	GO:0008168//methyltransferase activity;GO:0008171//O-methyltransferase activity	GO:0032259//methylation;GO:0043414//macromolecule methylation	--
ENSG00000286219	7.58	6.088	6.686	5.178	6.043	5.285	1218.63	1010.99	830.86	685.77	912.07	635.63	NOTCH2NLC	notch 2 N-terminal like C [Source:HGNC Symbol;Acc:HGNC:53924]	-	-	-	-	GO:0005576//extracellular region	GO:0005509//calcium ion binding;GO:0005515//protein binding	GO:0007219//Notch signaling pathway;GO:0021987//cerebral cortex development;GO:0045747//positive regulation of Notch signaling pathway	--
ENSG00000286221	0.075	0.095	0	0	0	0.158	4	4.05	0	0	0	3.19	CMC2	novel protein	-	-	-	-	GO:0005739//mitochondrion	-	-	--
ENSG00000286224	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000286231	0	0	0.138	0.381	0	0	0	0	3.2	8.88	0	0	MTARC1	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0030151//molybdenum ion binding;GO:0030170//pyridoxal phosphate binding	-	--
ENSG00000286235	0	0	0.456	0	0.245	0	0	0	40.96	0	25.13	0	MCM8	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005694//chromosome;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0016887//ATP hydrolysis activity"	GO:0008654//phospholipid biosynthetic process;GO:0032508//DNA duplex unwinding	--
ENSG00000286237	0.619	0.496	0.635	0.46	0.577	0.455	71.63	57.7	54.33	39.44	56.47	38.29	ARMCX5-GPRASP2	ARMCX5-GPRASP2 readthrough [Source:NCBI gene (formerly Entrezgene);Acc:100528062]	-	-	-	-	-	-	-	--
ENSG00000286239	0.443	0.136	0.144	0.124	0.153	0.17	31.5	9.73	7.57	6.55	9.22	8.79	WDFY1	"novel protein, WDFY1-AP1S3 readthrough"	-	-	-	-	-	-	-	--
ENSG00000286264	1.473	0.722	1.782	1.581	1.757	1.224	35.68	18.66	28.68	31.12	38.25	24.34	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000286268	0.084	0	0.056	0.058	0.153	0	2.49	0	1.23	1.27	3.82	0	EBP	novel protein	Metabolism;Metabolism	Global and overview maps;Lipid metabolism	ko01100//Metabolic pathways;ko00100//Steroid biosynthesis	K01824;K01824	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0110165//cellular anatomical entity	GO:0047750//cholestenol delta-isomerase activity	GO:0016125//sterol metabolic process	--
ENSG00000286522	0	0	0	0	0	0	0	0	0	0	0	0	H3C2	H3 clustered histone 2 [Source:HGNC Symbol;Acc:HGNC:4776]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000286905	0.487	0.653	0.355	0.275	0.188	0.178	27.48	36.55	14.74	11.24	9.04	7.12	RNASEH1	novel protein	Genetic Information Processing	Replication and repair	ko03030//DNA replication	K03469	-	GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0004519//endonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0016787//hydrolase activity;GO:0046872//metal ion binding	"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic"	--
ENSG00000286920	0	0	0	0	0	0	0	0	0	0	0	0	SMIM40	small integral membrane protein 40 [Source:HGNC Symbol;Acc:HGNC:54073]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000287080	0	0	0	0	0	0	0	0	0	0	0	0	H3C3	H3 clustered histone 3 [Source:HGNC Symbol;Acc:HGNC:4768]	Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases	Cancer: overview;Immune system;Infectious disease: bacterial;Immune disease;Substance dependence	ko05202//Transcriptional misregulation in cancer;ko04613//Neutrophil extracellular trap formation;ko05131//Shigellosis;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism	K11253;K11253;K11253;K11253;K11253	GO:0000228//nuclear chromosome;GO:0000786//nucleosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0016020//membrane;GO:0032991//protein-containing complex;GO:0070062//extracellular exosome	GO:0003677//DNA binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0046982//protein heterodimerization activity	"GO:0006333//chromatin assembly or disassembly;GO:0006334//nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0032200//telomere organization;GO:0040029//regulation of gene expression, epigenetic"	--
ENSG00000287363	0	0	0	0	0	0	0	0	0	0	0	0	GUCA1ANB	GUCA1A neighbor [Source:HGNC Symbol;Acc:HGNC:55126]	-	-	-	-	-	-	-	--
ENSG00000287542	1.637	1.675	1.531	1.392	1.17	1.154	168.68	173.45	116.51	106.21	101.81	86.49	HERC3	novel protein	Genetic Information Processing	"Folding, sorting and degradation"	ko04120//Ubiquitin mediated proteolysis	K10614	-	GO:0004842//ubiquitin-protein transferase activity	GO:0016567//protein ubiquitination	--
ENSG00000287585	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein, similar to CXorf51A"	Metabolism;Cellular Processes;Metabolism	Global and overview maps;Transport and catabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko04142//Lysosome;ko00531//Glycosaminoglycan degradation	K01136;K01136;K01136	-	-	-	--
ENSG00000287694	0	0	0	0	0	0	0	0	0	0	0	0	CNTNAP4	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	GO:0007155//cell adhesion	--
ENSG00000287725	0.017	0.019	0	0	0.019	0	1.65	1.81	0	0	1.54	0	TPCN2	"novel protein, TPCN2 - SMIM38 readthrough"	Environmental Information Processing;Organismal Systems	Signal transduction;Digestive system	ko04020//Calcium signaling pathway;ko04972//Pancreatic secretion	K14077;K14077	GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005216//ion channel activity;GO:0022832//voltage-gated channel activity	GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport	--
ENSG00000287856	0.074	0.697	0.137	0	0	0	2.09	19.77	6.91	0	0	0	EGLN1	novel protein	Human Diseases;Environmental Information Processing;Human Diseases	Cancer: overview;Signal transduction;Cancer: specific types	ko05200//Pathways in cancer;ko04066//HIF-1 signaling pathway;ko05211//Renal cell carcinoma	K09592;K09592;K09592	-	"GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0031418//L-ascorbic acid binding;GO:0046872//metal ion binding;GO:0051213//dioxygenase activity"	-	--
ENSG00000287908	0	0	0.032	0	0.029	0	0	0	1.37	0	1.43	0	ARHGEF25	novel protein	-	-	-	-	-	GO:0005085//guanyl-nucleotide exchange factor activity	GO:0035023//regulation of Rho protein signal transduction;GO:0050790//regulation of catalytic activity	--
ENSG00000288000	0	0	0	0	0	0	0	0	0	0	0	0	L3MBTL1	novel protein	-	-	-	-	GO:0005634//nucleus	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000288053	0	0.176	0	0	0	0.084	0	5.25	0	0	0	1.82	WDR45	novel protein	-	-	-	-	GO:0000407//phagophore assembly site;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0005515//protein binding	GO:0006914//autophagy	--
ENSG00000288208	0	0	0.199	0.325	0	0	0	0	8.42	13.84	0	0	MUTYH	novel protein	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K03575	-	"GO:0000166//nucleotide binding;GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0003824//catalytic activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0046872//metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding"	GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0006974//cellular response to DNA damage stimulus;GO:0008152//metabolic process	--
ENSG00000288258	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288460	0	0	0	0	0	0	0	0	0	0	0	0	SMIM42	small integral membrane protein 42 [Source:HGNC Symbol;Acc:HGNC:55000]	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288520	0	0.117	0.099	0.097	0.168	0	0	6.6	4.08	4.01	7.94	0	CNK3/IPCEF1	novel protein	-	-	-	-	GO:0005737//cytoplasm;GO:0016020//membrane	GO:0005515//protein binding	GO:0009966//regulation of signal transduction;GO:2001114//positive regulation of cellular response to hepatocyte growth factor stimulus	--
ENSG00000288529	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288534	0.905	2.272	4.954	9.814	1.642	7.307	97.17	247.82	395.73	788.81	151.18	582.65	TMX2	TMX2-CTNND1 readthrough (NMD candidate)	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288550	0.043	0	0	0.121	0.128	0	3.44	0	0	6.3	8.35	0	IL17RC	novel protein	Environmental Information Processing;Human Diseases;Organismal Systems	Signaling molecules and interaction;Endocrine and metabolic disease;Immune system	ko04060//Cytokine-cytokine receptor interaction;ko04936//Alcoholic liver disease;ko04657//IL-17 signaling pathway	K05166;K05166;K05166	-	GO:0030368//interleukin-17 receptor activity	GO:0019221//cytokine-mediated signaling pathway	--
ENSG00000288558	1.097	0.849	0.824	0.789	1.098	1.109	156.36	120.56	84.08	81.75	124.28	106.76	DUS4L-BCAP29	DUS4L-BCAP29 readthrough [Source:HGNC Symbol;Acc:HGNC:54422]	-	-	-	-	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0003824//catalytic activity;GO:0016491//oxidoreductase activity;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding	GO:0002943//tRNA dihydrouridine synthesis;GO:0006886//intracellular protein transport;GO:0008033//tRNA processing;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport	--
ENSG00000288564	0	0	0	0	0	0.11	0	0	0	0	0	3.14	MRPL2	novel protein	Genetic Information Processing	Translation	ko03010//Ribosome	K02886	GO:0005840//ribosome	GO:0003735//structural constituent of ribosome	GO:0006412//translation	--
ENSG00000288570	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288591	0.047	0.047	0.067	0.086	0.08	0.021	6.77	6.78	7.08	9.14	9.59	2.23	TBC1D30	novel protein	-	-	-	-	GO:0005829//cytosol;GO:0005886//plasma membrane	-	-	--
ENSG00000288602	0.437	0.436	0.437	0.522	0.435	0.396	14.81	26.79	19.73	23.67	15.67	17.61	C8orf44-SGK3	C8orf44-SGK3 readthrough [Source:HGNC Symbol;Acc:HGNC:48354]	Environmental Information Processing;Environmental Information Processing	Signal transduction;Signal transduction	ko04151//PI3K-Akt signaling pathway;ko04068//FoxO signaling pathway	K13304;K13304	-	GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016740//transferase activity;GO:0035091//phosphatidylinositol binding	GO:0006468//protein phosphorylation;GO:0016310//phosphorylation	--
ENSG00000288607	0	0	0	0	0	0	0	0	0	0	0	0	ELOA3BP	"elongin A3 family member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:31007]"	-	-	-	-	GO:0005634//nucleus;GO:0070449//elongin complex	-	GO:0006368//transcription elongation from RNA polymerase II promoter	--
ENSG00000288608	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288611	0	0.057	0.047	0	0.041	0	0	5	3	0	3	0	NPBWR1	neuropeptides B and W receptor 1 [Source:HGNC Symbol;Acc:HGNC:4522]	Environmental Information Processing	Signaling molecules and interaction	ko04080//Neuroactive ligand-receptor interaction	K05268	GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045202//synapse	GO:0004930//G protein-coupled receptor activity;GO:0004985//G protein-coupled opioid receptor activity;GO:0005515//protein binding;GO:0008188//neuropeptide receptor activity;GO:0042277//peptide binding;GO:0042923//neuropeptide binding	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007268//chemical synaptic transmission;GO:0019222//regulation of metabolic process;GO:0038003//G protein-coupled opioid receptor signaling pathway	--
ENSG00000288614	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288616	0	0	0	0	0	0	0	0	0	0	0	0	ELOA3DP	"elongin A3 family member D, pseudogene [Source:HGNC Symbol;Acc:HGNC:33511]"	-	-	-	-	GO:0005634//nucleus;GO:0070449//elongin complex	-	GO:0006368//transcription elongation from RNA polymerase II promoter	--
ENSG00000288622	0.222	0	0.346	0.431	0	0	26.76	0	30.87	38.53	0	0	PDCD6-AHRR	PDCD6-AHRR readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:54724]	-	-	-	-	-	GO:0005509//calcium ion binding;GO:0046872//metal ion binding	-	--
ENSG00000288623	0	0.072	0	0	0	0	0	0.39	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288625	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288626	0	0.239	0	0	0	0	0	1.03	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288629	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288631	0	0	0	0	0	0	0	0	0	0	0	0	ELOA3	elongin A3	-	-	-	-	GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070449//elongin complex	-	GO:0006368//transcription elongation from RNA polymerase II promoter	--
ENSG00000288634	0	1.421	0	0.393	0	0	0	4.71	0	0.96	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288635	0	0	0	0	0	0	0	0	0	0	0	0	ST7	"novel protein, readthrough ST7-OT4 - ST7"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288636	0	0	0	1.836	0	0	0	0	0	8.8	0	0	--	novel  protein	-	-	-	-	-	-	-	--
ENSG00000288637	0	0.052	0	0	0	0	0	3.22	0	0	0	0	TRIM2	novel protein	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm	GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding	-	--
ENSG00000288640	0.241	0.324	0.481	0.238	0.16	0.206	12.64	21.17	20.85	11.46	7.08	9.74	IFRD1	novel protein	-	-	-	-	-	-	-	--
ENSG00000288642	0	0.061	0	0	0	0	0	1	0	0	0	0	CDR1	cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798]	-	-	-	-	-	GO:0005515//protein binding	-	--
ENSG00000288643	0	0	0	0	0	0	0	0	0	0	0	0	--	novel transcript	-	-	-	-	-	-	-	--
ENSG00000288644	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288645	0	0.107	0	0	0	0	0	0.87	0	0	0	0	--	novel protein	Organismal Systems;Cellular Processes;Cellular Processes;Organismal Systems	Immune system;Cell growth and death;Cell growth and death;Digestive system	ko04621//NOD-like receptor signaling pathway;ko04217//Necroptosis;ko04218//Cellular senescence;ko04978//Mineral absorption	K04982;K04982;K04982;K04982	-	-	-	--
ENSG00000288646	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288649	0.457	0.545	0.206	0.329	0.541	0.753	15	18	5	8	15	18	ACTL10	actin like 10 [Source:HGNC Symbol;Acc:HGNC:16127]	-	-	-	-	GO:0005869//dynactin complex	-	-	--
ENSG00000288654	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288656	0.443	0.067	0.76	0.642	1.739	0.7	20.32	4	22.84	16.23	53.72	23.27	SULT1A2	novel protein	Human Diseases	Cancer: overview	ko05204//Chemical carcinogenesis - DNA adducts	K01014	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008146//sulfotransferase activity;GO:0016740//transferase activity	GO:1901135//carbohydrate derivative metabolic process;GO:1901564//organonitrogen compound metabolic process	--
ENSG00000288658	0.016	0	0	0.022	0.019	0	1	0	0	1	1	0	Trim3	"novel protein, ortholog of Gm2102 (M. musculus)"	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0046872//metal ion binding	-	--
ENSG00000288661	0	0	0.711	0	0.314	0	0	0	1.96	0	0.99	0	--	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288669	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein, readthrough CD209 - CLEC4G"	-	-	-	-	-	-	-	--
ENSG00000288671	0	0	0	0	0	0	0	0	0	0	0	0	GSK3A	novel protein	Human Diseases;Organismal Systems;Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system;Endocrine and metabolic disease;Nervous system	ko05131//Shigellosis;ko04062//Chemokine signaling pathway;ko04932//Non-alcoholic fatty liver disease;ko04728//Dopaminergic synapse	K08822;K08822;K08822;K08822	-	-	-	--
ENSG00000288674	0.279	0.397	0.29	0.262	0.167	0.251	54.91	78.63	42.13	38.25	27.86	30.83	PSEN2	Novel protein	Human Diseases;Human Diseases;Organismal Systems;Environmental Information Processing	Neurodegenerative disease;Neurodegenerative disease;Nervous system;Signal transduction	ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko04722//Neurotrophin signaling pathway;ko04330//Notch signaling pathway	K04522;K04522;K04522;K04522	-	-	-	--
ENSG00000288675	0.23	0.228	0.207	0.349	0.238	0.118	8	8	5.32	9	7	3	PANO1	proapoptotic nucleolar protein 1 [Source:HGNC Symbol;Acc:HGNC:51237]	-	-	-	-	GO:0005634//nucleus;GO:0005730//nucleolus	-	GO:0006915//apoptotic process;GO:0031647//regulation of protein stability;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process	--
ENSG00000288677	0	0	0	0	0	0	0	0	0	0	0	0	HRURF	HR upstream open reading frame [Source:HGNC Symbol;Acc:HGNC:55085]	-	-	-	-	-	-	-	--
ENSG00000288678	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288681	0	0	0	0	0	0	0	0	0	0	0	0	IFITM1	novel protein	Organismal Systems	Immune system	ko04662//B cell receptor signaling pathway	K19831	GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288683	1.127	2.515	1.356	2.014	2.846	1.964	67.42	151.27	59.94	89.29	143.86	85.52	PEX26	"novel protein, PEX26-TUBA8"	Cellular Processes	Transport and catabolism	ko04146//Peroxisome	K13340	GO:0005779//integral component of peroxisomal membrane	GO:0044877//protein-containing complex binding	GO:0045046//protein import into peroxisome membrane	--
ENSG00000288684	0.82	0.514	1.031	0	0.247	0	81.96	51.92	77.46	0	21.24	0	DDX58	novel protein	Human Diseases;Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Signal transduction;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Infectious disease: viral;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05171//Coronavirus disease - COVID-19;ko05169//Epstein-Barr virus infection;ko04064//NF-kappa B signaling pathway;ko05164//Influenza A;ko05161//Hepatitis B;ko05160//Hepatitis C;ko05162//Measles;ko04622//RIG-I-like receptor signaling pathway;ko04623//Cytosolic DNA-sensing pathway	K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646;K12646	GO:0005737//cytoplasm	GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016787//hydrolase activity;GO:0016887//ATP hydrolysis activity;GO:0046872//metal ion binding	GO:0002376//immune system process;GO:0045087//innate immune response;GO:0051607//defense response to virus	--
ENSG00000288695	0.088	0	0.115	0.051	0.02	0.124	4.88	0	4.71	2.08	1.51	5.02	SRD5A3	"novel protein, SRD5A3-RP11-177J6.1 readthrough"	Metabolism;Metabolism;Metabolism	Global and overview maps;Lipid metabolism;Glycan biosynthesis and metabolism	ko01100//Metabolic pathways;ko00140//Steroid hormone biosynthesis;ko00510//N-Glycan biosynthesis	K12345;K12345;K12345	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	"GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0102389//polyprenol reductase activity"	GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0016095//polyprenol catabolic process;GO:0019348//dolichol metabolic process	--
ENSG00000288698	0	0.289	0.13	0.399	0	0	0	19.03	6.3	19.38	0	0	NDUFB5	novel protein	Metabolism;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Metabolism	Global and overview maps;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Neurodegenerative disease;Environmental adaptation;Cancer: overview;Cardiovascular disease;Endocrine and metabolic disease;Nervous system;Energy metabolism	ko01100//Metabolic pathways;ko05022//Pathways of neurodegeneration - multiple diseases;ko05010//Alzheimer disease;ko05014//Amyotrophic lateral sclerosis;ko05016//Huntington disease;ko05020//Prion disease;ko05012//Parkinson disease;ko04714//Thermogenesis;ko05208//Chemical carcinogenesis - reactive oxygen species;ko05415//Diabetic cardiomyopathy;ko04932//Non-alcoholic fatty liver disease;ko04723//Retrograde endocannabinoid signaling;ko00190//Oxidative phosphorylation	K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961;K03961	GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	-	-	--
ENSG00000288699	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288701	74.286	78.499	87.687	76.889	78.051	97.873	12835.49	13252.9	9947.08	9595	11625	9256	PRRC2B	proline rich coiled-coil 2B [Source:HGNC Symbol;Acc:HGNC:28121]	-	-	-	-	-	GO:0003723//RNA binding;GO:0005515//protein binding	GO:0030154//cell differentiation	--
ENSG00000288702	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A3	UDP glucuronosyltransferase family 1 member A3 [Source:HGNC Symbol;Acc:HGNC:12535]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0001972//retinoic acid binding;GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity;GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity	GO:0006629//lipid metabolic process;GO:0008210//estrogen metabolic process;GO:0032782//bile acid secretion;GO:0042573//retinoic acid metabolic process;GO:0052695//cellular glucuronidation;GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation;GO:0070640//vitamin D3 metabolic process	--
ENSG00000288705	0	0	0	0	0	0	0	0	0	0	0	0	UGT1A5	UDP glucuronosyltransferase family 1 member A5 [Source:HGNC Symbol;Acc:HGNC:12537]	Metabolism;Human Diseases;Organismal Systems;Metabolism;Metabolism;Human Diseases;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism;Metabolism	Global and overview maps;Cancer: overview;Digestive system;Xenobiotics biodegradation and metabolism;Xenobiotics biodegradation and metabolism;Cancer: overview;Metabolism of cofactors and vitamins;Xenobiotics biodegradation and metabolism;Lipid metabolism;Metabolism of cofactors and vitamins;Carbohydrate metabolism;Carbohydrate metabolism	ko01100//Metabolic pathways;ko05207//Chemical carcinogenesis - receptor activation;ko04976//Bile secretion;ko00983//Drug metabolism - other enzymes;ko00980//Metabolism of xenobiotics by cytochrome P450;ko05204//Chemical carcinogenesis - DNA adducts;ko00830//Retinol metabolism;ko00982//Drug metabolism - cytochrome P450;ko00140//Steroid hormone biosynthesis;ko00860//Porphyrin metabolism;ko00040//Pentose and glucuronate interconversions;ko00053//Ascorbate and aldarate metabolism	K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699;K00699	GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane	GO:0008194//UDP-glycosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0016740//transferase activity;GO:0016757//glycosyltransferase activity	GO:0052696//flavonoid glucuronidation;GO:0052697//xenobiotic glucuronidation	--
ENSG00000288706	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288708	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288709	2.272	2.598	2.375	1.712	2.644	3.206	80.44	92.46	62.1	44.9	79.09	82.58	F8A2	coagulation factor VIII associated 2 [Source:HGNC Symbol;Acc:HGNC:31849]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0016604//nuclear body	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0099518//vesicle cytoskeletal trafficking;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000288710	0	0.17	0.531	0.221	0.423	0	0	4.99	16.99	4.76	15.44	0	KMT2D	novel protein	Metabolism;Human Diseases;Metabolism	Global and overview maps;Endocrine and metabolic disease;Amino acid metabolism	ko01100//Metabolic pathways;ko04934//Cushing syndrome;ko00310//Lysine degradation	K09187;K09187;K09187	GO:0005634//nucleus;GO:0031981//nuclear lumen	GO:0016740//transferase activity	GO:0006325//chromatin organization	--
ENSG00000288711	0	0	0	0	0	0	0	0	0	0	0	0	RCAN1	novel protein	Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Endocrine system;Endocrine system	ko05167//Kaposi sarcoma-associated herpesvirus infection;ko04921//Oxytocin signaling pathway;ko04919//Thyroid hormone signaling pathway	K17901;K17901;K17901	-	-	-	--
ENSG00000288712	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288715	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288716	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288721	0.114	0.043	0	0	0.136	0.024	8.71	3.27	0	0	2.84	1.32	MED20	novel protein	-	-	-	-	-	-	-	--
ENSG00000288722	8.985	8.966	8.138	11.675	10.391	9.388	318.12	319.07	212.8	306.2	310.82	241.85	F8A1	coagulation factor VIII associated 1 [Source:HGNC Symbol;Acc:HGNC:3547]	-	-	-	-	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005769//early endosome;GO:0016604//nuclear body	GO:0003674//molecular_function;GO:0005515//protein binding	GO:0099518//vesicle cytoskeletal trafficking;GO:1901799//negative regulation of proteasomal protein catabolic process	--
ENSG00000288725	0	0	0	0	0	0	0	0	0	0	0	0	BBS2	novel protein	-	-	-	-	-	-	-	--
ENSG00000288784	1.407	0.9	0.853	0.587	0.565	0.393	76.29	49.04	34.19	23.57	25.87	15.5	CTAGE4	CTAGE family member 4 [Source:HGNC Symbol;Acc:HGNC:24772]	-	-	-	-	GO:0005575//cellular_component;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0008150//biological_process;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000288796	0	0	0	0	0	0	0	0	0	0	0	0	PPBP	novel protein	Environmental Information Processing;Organismal Systems;Environmental Information Processing	Signaling molecules and interaction;Immune system;Signaling molecules and interaction	ko04060//Cytokine-cytokine receptor interaction;ko04062//Chemokine signaling pathway;ko04061//Viral protein interaction with cytokine and cytokine receptor	K10029;K10029;K10029	GO:0005576//extracellular region	GO:0008009//chemokine activity	GO:0006935//chemotaxis;GO:0006952//defense response;GO:0006955//immune response	--
ENSG00000288825	4.523	5.759	7.226	8.059	6.959	5.451	50	64	59	66	65	43.85	H2AC18	H2A clustered histone 18 [Source:HGNC Symbol;Acc:HGNC:4736]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000288841	0.394	1.576	3.944	0	0	0	3.51	14.1	25.92	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288859	0	0	0	0	0	0	0	0	0	0	0	0	H2AC19	H2A clustered histone 19 [Source:HGNC Symbol;Acc:HGNC:29668]	Organismal Systems;Human Diseases;Human Diseases;Cellular Processes	Immune system;Immune disease;Substance dependence;Cell growth and death	ko04613//Neutrophil extracellular trap formation;ko05322//Systemic lupus erythematosus;ko05034//Alcoholism;ko04217//Necroptosis	K11251;K11251;K11251;K11251	GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0070062//extracellular exosome	GO:0003674//molecular_function;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity	GO:0008150//biological_process	--
ENSG00000288864	0.629	0.367	0.404	0.047	0.239	0.235	38.32	21.81	17.64	2.08	12.43	10.11	ARHGAP11A-SCG5	ARHGAP11A-SCG5 readthrough [Source:NCBI gene (formerly Entrezgene);Acc:114118903]	-	-	-	-	GO:0030141//secretory granule	-	GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway	--
ENSG00000288867	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4C	peptidylprolyl isomerase A like 4C [Source:HGNC Symbol;Acc:HGNC:33995]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000288894	0	0.34	0	0	0.123	0	0	15.38	0	0	4.66	0	DCAF7	novel protein	-	-	-	-	-	-	-	--
ENSG00000288914	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000288920	4.341	5.028	3.939	3.327	3.531	3.246	192.69	224.34	129.13	109.4	132.43	104.84	RPSAP58	ribosomal protein SA pseudogene 58 [Source:HGNC Symbol;Acc:HGNC:36809]	Human Diseases;Genetic Information Processing	Infectious disease: viral;Translation	ko05171//Coronavirus disease - COVID-19;ko03010//Ribosome	K02998;K02998	GO:0005840//ribosome;GO:0015935//small ribosomal subunit	GO:0003735//structural constituent of ribosome;GO:0005055//laminin receptor activity	GO:0006412//translation	--
ENSG00000289025	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289027	0.194	0	0.333	0	0	0.226	21.62	0	27.39	0	0	18.34	KRIT1	novel protein	Environmental Information Processing;Organismal Systems	Signal transduction;Aging	ko04015//Rap1 signaling pathway;ko04212//Longevity regulating pathway - worm	K17705;K17705	GO:0005856//cytoskeleton	"GO:0004497//monooxygenase activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding"	-	--
ENSG00000289051	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	GO:0005739//mitochondrion	GO:0005515//protein binding	GO:0019516//lactate oxidation	--
ENSG00000289258	0	0	0	0	0	0	0	0	0	0	0	0	OPN4	novel protein	-	-	-	-	GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0097381//photoreceptor disc membrane	GO:0004930//G protein-coupled receptor activity;GO:0005515//protein binding;GO:0009881//photoreceptor activity	GO:0007165//signal transduction;GO:0007186//G protein-coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007602//phototransduction;GO:0018298//protein-chromophore linkage;GO:0050896//response to stimulus	--
ENSG00000289281	0.133	0	0	0	0.078	0	2	0	0	0	1	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289282	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289325	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289346	1.34	0.901	0.883	1.314	1.218	1.72	120.81	81.64	58.82	87.74	92.73	112.79	GTF2IRD2	Novel protein	-	-	-	-	GO:0005634//nucleus	-	-	--
ENSG00000289360	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	Metabolism;Metabolism	Global and overview maps;Amino acid metabolism	ko01100//Metabolic pathways;ko00310//Lysine degradation	K09189;K09189	-	-	-	--
ENSG00000289490	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289491	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289503	0.022	0.134	0	0	0	0	1	6	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289517	0	0.25	0	0	0.272	0	0	23.58	0	0	21.56	0	CYB5R3	novel protein	Metabolism	Carbohydrate metabolism	ko00520//Amino sugar and nucleotide sugar metabolism	K00326	GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule	GO:0005515//protein binding	-	--
ENSG00000289549	0	0	0	0	0	0	0	0	0	0	0	0	PPIAL4D	peptidylprolyl isomerase A like 4D [Source:HGNC Symbol;Acc:HGNC:33998]	-	-	-	-	GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle	GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding;GO:0016853//isomerase activity	GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding	--
ENSG00000289565	0	0	0	0	0	0	0	0	0	0	0	0	RBM8A	novel protein	Genetic Information Processing;Genetic Information Processing;Genetic Information Processing	Transcription;Translation;Translation	ko03040//Spliceosome;ko03013//Nucleocytoplasmic transport;ko03015//mRNA surveillance pathway	K12876;K12876;K12876	GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck	GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0003729//mRNA binding	"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0051028//mRNA transport"	--
ENSG00000289604	1.149	0.909	0.946	0.587	1.413	1.246	62.31	49.58	37.91	23.57	64.77	49.19	CTAGE8	CTAGE family member 8 [Source:HGNC Symbol;Acc:HGNC:37294]	-	-	-	-	GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070971//endoplasmic reticulum exit site	-	GO:0006888//endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306//protein secretion;GO:0035459//vesicle cargo loading	--
ENSG00000289685	8.753	7.763	8.675	8.493	8.59	10.258	602.71	537	441	436.09	499.72	514.44	MRPS5	mitochondrial ribosomal protein S5 [Source:HGNC Symbol;Acc:HGNC:14498]	Genetic Information Processing	Translation	ko03010//Ribosome	K02988	GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005763//mitochondrial small ribosomal subunit;GO:0005840//ribosome	GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome	GO:0006412//translation;GO:0032543//mitochondrial translation	--
ENSG00000289690	0	0	0	0.218	0	0	0	0	0	9.33	0	0	MEPCE	novel transcript	-	-	-	-	-	GO:0008168//methyltransferase activity	-	--
ENSG00000289692	0	0	0	0	0.396	0	0	0	0	0	3.92	0	C1QA	novel protein	Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Organismal Systems;Human Diseases	Infectious disease: viral;Neurodegenerative disease;Immune disease;Infectious disease: bacterial;Endocrine and metabolic disease;Infectious disease: parasitic;Immune system;Infectious disease: bacterial	ko05171//Coronavirus disease - COVID-19;ko05020//Prion disease;ko05322//Systemic lupus erythematosus;ko05150//Staphylococcus aureus infection;ko04936//Alcoholic liver disease;ko05142//Chagas disease;ko04610//Complement and coagulation cascades;ko05133//Pertussis	K03986;K03986;K03986;K03986;K03986;K03986;K03986;K03986	-	GO:0005515//protein binding	"GO:0006958//complement activation, classical pathway"	--
ENSG00000289694	52.56	48.647	49.984	47.575	44.863	53.755	2377.74	2212.04	1670.05	1594.2	1714.65	1769.36	CDC42	novel protein	Human Diseases;Human Diseases;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Environmental Information Processing;Cellular Processes;Environmental Information Processing;Human Diseases;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Organismal Systems;Organismal Systems;Cellular Processes;Organismal Systems;Human Diseases;Organismal Systems;Organismal Systems;Organismal Systems;Human Diseases;Organismal Systems;Human Diseases;Human Diseases;Human Diseases;Cellular Processes;Human Diseases;Environmental Information Processing	Cancer: overview;Infectious disease: viral;Signal transduction;Infectious disease: bacterial;Infectious disease: bacterial;Infectious disease: bacterial;Transport and catabolism;Signal transduction;Cell motility;Signal transduction;Cardiovascular disease;Infectious disease: bacterial;Cancer: overview;Cancer: overview;Cellular community - eukaryotes;Immune system;Development and regeneration;Cellular community - eukaryotes;Immune system;Endocrine and metabolic disease;Nervous system;Immune system;Immune system;Endocrine and metabolic disease;Endocrine system;Infectious disease: bacterial;Cancer: specific types;Cancer: specific types;Cellular community - eukaryotes;Infectious disease: bacterial;Signal transduction	ko05200//Pathways in cancer;ko05165//Human papillomavirus infection;ko04010//MAPK signaling pathway;ko05130//Pathogenic Escherichia coli infection;ko05132//Salmonella infection;ko05131//Shigellosis;ko04144//Endocytosis;ko04014//Ras signaling pathway;ko04810//Regulation of actin cytoskeleton;ko04015//Rap1 signaling pathway;ko05417//Lipid and atherosclerosis;ko05135//Yersinia infection;ko05205//Proteoglycans in cancer;ko05203//Viral carcinogenesis;ko04510//Focal adhesion;ko04062//Chemokine signaling pathway;ko04360//Axon guidance;ko04530//Tight junction;ko04666//Fc gamma R-mediated phagocytosis;ko04932//Non-alcoholic fatty liver disease;ko04722//Neurotrophin signaling pathway;ko04670//Leukocyte transendothelial migration;ko04660//T cell receptor signaling pathway;ko04933//AGE-RAGE signaling pathway in diabetic complications;ko04912//GnRH signaling pathway;ko05100//Bacterial invasion of epithelial cells;ko05212//Pancreatic cancer;ko05211//Renal cell carcinoma;ko04520//Adherens junction;ko05120//Epithelial cell signaling in Helicobacter pylori infection;ko04370//VEGF signaling pathway	K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393;K04393	GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030496//midbody;GO:0043227//membrane-bounded organelle;GO:0071944//cell periphery	GO:0000166//nucleotide binding;GO:0003924//GTPase activity;GO:0003925//G protein activity;GO:0005525//GTP binding	GO:0007163//establishment or maintenance of cell polarity;GO:0007264//small GTPase mediated signal transduction;GO:0009653//anatomical structure morphogenesis;GO:0051130//positive regulation of cellular component organization;GO:0051301//cell division	--
ENSG00000289695	0	0	0	0	0	0	0	0	0	0	0	0	METTL7A	novel protein	-	-	-	-	-	-	-	--
ENSG00000289697	7.603	8.024	8.685	7.603	7.562	6.119	228.68	242.56	194.34	169.39	192.14	133.9	CFH	novel protein	Human Diseases;Organismal Systems	Infectious disease: bacterial;Immune system	ko05150//Staphylococcus aureus infection;ko04610//Complement and coagulation cascades	K04004;K04004	-	-	-	--
ENSG00000289700	0.326	0.4	0.904	0.258	0.364	0.841	39.15	48.27	80.19	22.96	36.88	73.5	IRF6	novel protein	-	-	-	-	-	GO:0000976//transcription cis-regulatory region binding;GO:0003700//DNA-binding transcription factor activity;GO:0005515//protein binding	"GO:0006355//regulation of transcription, DNA-templated"	--
ENSG00000289701	0.031	0.135	0.134	0.163	0.136	0.153	2.64	11.41	8.31	10.16	9.67	9.35	CARD9	novel transcript	Human Diseases;Human Diseases;Organismal Systems;Organismal Systems	Infectious disease: viral;Infectious disease: bacterial;Immune system;Immune system	ko05168//Herpes simplex virus 1 infection;ko05152//Tuberculosis;ko04621//NOD-like receptor signaling pathway;ko04625//C-type lectin receptor signaling pathway	K12794;K12794;K12794;K12794	-	-	GO:0042981//regulation of apoptotic process	--
ENSG00000289710	0	0	0	0	0	0	0	0	0	0	0	0	--	"novel protein, similar to CD24 molecule CD52"	-	-	-	-	-	-	-	--
ENSG00000289715	0	0	0	0	0	0	0	0	0	0	0	0	--	novel protein	-	-	-	-	-	-	-	--
ENSG00000289716	0.119	0.163	0.28	0.105	0.229	0.106	10.34	14.28	18	6.74	16	6	XNDC1N-ZNF705EP-ALG1L9P	XNDC1N-ZNF705EP-ALG1L9P readthrough [Source:HGNC Symbol;Acc:HGNC:55871]	Genetic Information Processing	Replication and repair	ko03410//Base excision repair	K10803	-	-	-	--